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Archive, 2023-10

4 Hyperbolic graph embedding of MEG brain networks to study brain alterations in individuals with subjective cognitive decline
Baker, C.; Mendez, I. S.; Smith, G.; Marsh, E. B.; Funke, M.; Mosher, J. C.; Maestu, F.; Xu, M.; Pantazis, D.
10.1101/2023.10.23.563643 — bioinformatics — Posted on 2023-10-31
10 Tracing the substrate translocation mechanism in P-glycoprotein
Gewering, T.; Waghray, D.; Parey, K.; Jung, H.; Tran, N. N. B.; Zapata, J.; Zhao, P.; Chen, H.; Januliene, D.; Hummer, G.; Urbatsch, I. L.; Moeller, A.; Zhang, Q.
10.1101/2022.04.28.489897 — biophysics — Posted on 2023-10-31
16 Dynamic in vivo mapping of the methylproteome using a chemoenzymatic approach
Farhi, J.; Jones, R. B.; Lee, R. S.; Verma, A. K.; Parwani, K. K.; Emenike, B.; Tang, K.-C.; Bagchi, P.; Raj, M.; Spangle, J.
10.1101/2022.07.22.501130 — biochemistry — Posted on 2023-10-31
22 Nuclear eDNA Metabarcoding Primers for Anthozoan Coral Biodiversity Assessment
McCartin, L. J.; Saso, E.; Vohsen, S. A.; Pittoors, N. C.; Demetriades, P.; McFadden, C. S.; Quattrini, A. M.; Herrera, S.
10.1101/2023.10.26.564240 — ecology — Posted on 2023-10-31
23 Integrated Computational Biophysics approach for Drug Discovery against Nipah Virus
Palacios, G. R.; Zuta, M. C.; Galarza, J. P. R.; Villarreal, E. G.; Silva, J. P.; Otazu, K.; Aguila, I. N. d.; Wong, H. D.; Amay, F. S.; Dattani, N.; Camps, I.; Patil, R. B.; Moin, A. T.
10.1101/2023.10.23.563595 — microbiology — Posted on 2023-10-31
25 Biomimetic computations improve neural network robustness
Evanson, L.; Lavrov, M.; Kharitonov, I.; Lu, S.; Kozlov, A.
10.1101/2023.10.26.564127 — neuroscience — Posted on 2023-10-31
26 Multivariate and Regional Age-Related Change in Basal Ganglia Iron in Neonates
Cabral, L.; Calabro, F.; Foran, W.; Parr, A.; Ojha, A.; Rasmussen, J.; Ceschin, R.; Panigrahy, A.; Luna, B.
10.1101/2023.07.05.547821 — neuroscience — Posted on 2023-10-31
29 The Molecular Architecture of Variable Lifespan in Diversity Outbred Mice
Hackett, S. R.; Magzoub, M. M.; Maile, T. M.; Vu, N.; Wright, K. M.; Melamud, E.; Haas, W.; McAllister, F. E.; Churchill, G. A.; Bennett, B. D.
10.1101/2023.10.26.564069 — systems biology — Posted on 2023-10-31
30 Genome-wide evidence of the role of Paf1C in transcription elongation and histone H2B monoubiquitination in Arabidopsis
Blanco, N.; Perez-Alemany, J.; Bourbousse, C.; latrasse, D.; Ait-Mohamed, O.; Benhamed, M.; Barneche, F.; Blazquez, M. A.; Gallego-Bartolome, J.; Alabadi, D.
10.1101/2023.10.27.564443 — plant biology — Posted on 2023-10-31
35 Antisense Oligonucleotide Targeting Hepatic Serum Amyloid A Limits the Progression of Angiotensin II-Induced Abdominal Aortic Aneurysm Formation
Shridas, P.; Ji, A.; Trumbauer, A. C.; Noffsinger, V. P.; Meredith, L. W.; de Beer, F. C.; Mullick, A. E.; Webb, N. R.; Karounos, D. G.; Tannock, L. R.
10.1101/2023.08.22.554377 — pathology — Posted on 2023-10-31
37 The Colibactin-Producing Escherichia coli alters the tumor microenvironment to immunosuppressive lipid overload facilitating colorectal cancer progression and chemoresistance.
de Oliveira Alves, N.; Dalmasso, G.; Nikitina, D.; Vaysse, A.; Ruez, R.; Ledoux, L.; Pedron, T.; Bergstein, E.; Boulard, O.; Autier, L.; Allam, S.; Motreff, L.; Sauvanet, P.; Letourneur, D.; Gagniere, J.; Pezet, D.; Godfraind, C.; Salzet, M.; Lemichez, E.; Najjar, I.; Malabat, C.; Monot, M.; Mestivier, D.; Barnich, N.; Fournier, I.; Kennedy, S.; Mettouchi, A.; Bonnet, R.; Sobhani, I.; Chamaillard, M.
10.1101/2023.03.13.523827 — cancer biology — Posted on 2023-10-31
44 Linking collective migration/growth to differentiation boosts global shaping of the transcriptome and exhibits a grasshopper effect for driving maturation
Ogoke, O.; Guiggey, D.; Chiang, A.; Thompson, S.; Nguyen, T. H. A.; Berke, D.; Ott, C.; Kalinousky, A.; Shamul, C.; Chen, P.; Ross, S.; Chen, Z.; Srivastava, P.; Gaughan, C.; Mahajan, S. D.; Zhao, R.; Gunawan, R.; Parashurama, N.
10.1101/2022.07.24.501313 — bioengineering — Posted on 2023-10-31
46 Remarkably high repeat content in the genomes of sparrows: the importance of genome assembly completeness for transposable element discovery.
Benham, P.; Cicero, C.; Escalona, M.; Beraut, E.; Fairbairn, C.; Marimuthu, M. P. A.; Nguyen, O.; Sahasrabudhe, R.; King, B. L.; Thomas, W. K.; Kovach, A. I.; Nachman, M. W.; Bowie, R. C. K.
10.1101/2023.10.26.564301 — genomics — Posted on 2023-10-31
47 Large scale sequence-based screen for recessive variants allows for identification and monitoring of rare deleterious variants in pigs
Boshove, A.; Derks, M. F. L.; Sevillano, C. A.; Lopes, M. S.; van Son, M.; Knol, E. F.; Dibbits, B.; Harlizius, B.
10.1101/2023.10.26.564309 — genomics — Posted on 2023-10-31
48 Linked-Pair Long-Read Sequencing Strategy for Targeted Resequencing and Enrichment
Uppuluri, L.; Shi, C. H.; Varapula, D. T.; Young, E.; Ehrlich, R. L.; Wang, Y.; Piazza, D.; Mell, J. C.; Yip, K.; Xiao, M.
10.1101/2023.10.26.564243 — genomics — Posted on 2023-10-31
50 Integrative chromatin state annotation of 234 human ENCODE4 cell types using Segway reveals disease drivers
Farahbod, M.; Diab, A. R.; Sud, P.; Shahraki, M. F.; Daneshpajouh, H.; Goel, I.; Kagda, M.; Whaling, I.; Hitz, B.; Cherry, J. M.; Libbrecht, M. W.
10.1101/2023.10.26.564254 — genomics — Posted on 2023-10-31
53 Adaptive divergence in the eyes of Heliconius butterflies likely contributes to pre- and post mating isolation
Wright, D. S.; Rodriguez-Fuentes, J.; Ammer, L.; Darragh, K.; Kuo, C.-Y.; McMillan, W. O.; Jiggins, C. D.; Montgomery, S. H.; Merrill, R. M.
10.1101/2023.10.26.564160 — evolutionary biology — Posted on 2023-10-31
55 Multi-modal skin atlas identifies a multicellular immune-stromal community associated with altered cornification and specific T cell expansion in atopic dermatitis
Fiskin, E.; Eraslan, G.; Alora-Palli, M. B.; Leyva-Castillo, J. M.; Kim, S.; Choe, H.; Lareau, C. A.; Lau, H.; Finan, E. P.; Teixeira-Soldano, I.; LaBere, B.; Chu, A.; Woods, B.; Chou, J.; Slyper, M.; Waldman, J.; Islam, S.; Schneider, L.; Phipatanakul, W.; Platt, C.; Rozenblatt-Rosen, O.; Delorey, T. M.; Deguine, J.; Smith, G. P.; Geha, R. S.; Regev, A.; Xavier, R. J.
10.1101/2023.10.29.563503 — molecular biology — Posted on 2023-10-31
58 Pericyte ablation causes hypoactivity and reactive gliosis in adult mice
Cashion, J. M.; Brown, L. S.; Morris, G. P.; Fortune, A. J.; Courtney, J.-M.; Cullen, C. L.; Young, K. M.; Sutherland, B. A.
10.1101/2023.10.26.564269 — neuroscience — Posted on 2023-10-31
59 Parabrachial Calca neurons drive nociplasticity
Condon, L. F.; Yu, Y.; Park, S.; Cao, F.; Pauli, J. L.; Nelson, T. S.; Palmiter, R. D.
10.1101/2023.10.26.564223 — neuroscience — Posted on 2023-10-31
62 Criticality of resting-state EEG predicts perturbational complexity and level of consciousness during anesthesia
Maschke, C.; O'Byrne, J.; Colombo, M. A.; Boly, M.; Gosseries, O.; Laureys, S.; Rosanova, M.; Jerbi, K.; Blain-Moraes, S.
10.1101/2023.10.26.564247 — neuroscience — Posted on 2023-10-31
66 Graph attention-based fusion of pathology images and gene expression for prediction of cancer survival
Zheng, Y.; Conrad, R. D.; Green, E. J.; Burks, E. J.; Betke, M.; Beane, J. E.; Kolachalama, V. B.
10.1101/2023.10.26.564236 — bioinformatics — Posted on 2023-10-31
69 Human iPSC-derived microglia sense and dampen hyperexcitability of cortical neurons carrying the epilepsy-associated SCN2A-L1342P mutation
Que, Z.; Olivero-Acosta, M.; Chen, I.; Zhang, J.; Wettschurack, K.; Wu, J.; Xiao, T.; Otterbacher, C. M.; Wang, M.; Harlow, H.; Cui, N.; Chen, X.; Deming, B.; Halurkar, M.; Zhao, Y.; Rochet, J.-C.; Xu, R.; Brewster, A.; Wu, L.-J.; Yuan, C.; Skarnes, W. C.; Yang, Y.
10.1101/2023.10.26.563426 — neuroscience — Posted on 2023-10-31
71 Perilipin membrane association determines Lipid Droplet heterogeneity in differentiating adipocytes
Majchrzak, M.; Stojanovic, O.; Ajjaji, D.; Ben M'barek, K.; Omrane, M.; THIAM, A. R.; Klemm, R. W.
10.1101/2023.10.30.564726 — cell biology — Posted on 2023-10-31
72 Whole-genome duplication in an algal symbiont bolsters coral heat tolerance
Dougan, K. E.; Bellantuono, A. J.; Kahlke, T.; Abbriano, R. M.; Chen, Y.; Shah, S.; Granados-Cifuentes, C.; van Oppen, M. J. H.; Bhattacharya, D.; Suggett, D. J.; Rodriguez-Lanetty, M.; Chan, C. X.
10.1101/2022.04.10.487810 — genomics — Posted on 2023-10-31
73 Pithoviruses are invaded by repeats that contribute to their evolution and divergence from cedratviruses
Rigou, S.; Schmitt, A.; Alempic, J.-M.; Lartigue, A.; Vendloczki, P.; Abergel, C.; Claverie, J.-M.; Legendre, M.
10.1101/2023.03.08.530996 — genomics — Posted on 2023-10-31
75 Finite Sample Adjustments for Average Equivalence Testing
Boulaguiem, Y.; Quartier, J.; Lapteva, M.; Kalia, Y. N.; Victoria-Feser, M.-P.; Guerrier, S.; Couturier, D.-L.
10.1101/2023.03.11.532179 — pharmacology and toxicology — Posted on 2023-10-31
76 Neoadjuvant Therapy Differentially Remodels Carcinoma and Tumor Microenvironment in Pancreatic Ductal Adenocarcinoma: Insights from Spatially Resolved Transcriptomics
Zhang, X.; Liu, Y.-Z.; Lan, R.; Liu, Y.; Pillarisetty, V. G.; Li, D.; Zhao, C. L.; Sarkar, S.; Liu, W.; Hanna, I.; Gupta, M.; Hajdu, C.; Melamed, J.; Widmer, J.; Allendorf, J.
10.1101/2023.10.26.564099 — cancer biology — Posted on 2023-10-31
79 The multilevel society of proboscis monkeys with a possible patrilineal basis
Matsuda, I.; Murai, T.; Grueter, C. C.; Tuuga, A.; Goossens, B.; Bernard, H.; Yahya, N. K.; Orozco-terWengel, P.; Salgado-Lynn, M.
10.1101/2023.01.24.525467 — animal behavior and cognition — Posted on 2023-10-31
80 Segmental Duplications Drive the Evolution of Accessory Regions in a Major Crop Pathogen
van Westerhoven, A.; Aguilera-Galvez, C.; Nakasato-Tagami, G.; Shi-Kunne, X.; Martinez de la Parte, E.; Chavarro Carero, E.; Meijer, H.; Feurtey, A.; Maryani, N.; Ordonez, N.; Schneider, H.; Nijbroek, K.; Wittenberg, A.; Hofstede, R.; Garcia-Bastidas, F.; Sorensen, A.; Swennen, R.; Stukenbrock, E.; Kema, G.; Seidl, M.
10.1101/2023.06.07.544053 — genomics — Posted on 2023-10-31
81 A chromosome-level genome assembly of Zasmidium syzygii isolated from banana leaves
van Westerhoven, A.; Mehrabi, R.; Talebi, R.; Steentjes, M.; Corcolon, B.; Chong, P.; Kema, G.; Seidl, M. F.
10.1101/2023.08.24.554682 — microbiology — Posted on 2023-10-31
84 A Gallium-68-Labeled Peptide Radiotracer For CD38-Targeted Imaging In Multiple Myeloma With PET
Sharma, A. K.; Gupta, K.; Mishra, A.; Lofland, G.; Marsh, I.; Kumar, D.; Ghiaur, G.; Imus, P.; Hobbs, R. F.; Gocke, C. B.; Nimmagadda, S.
10.1101/2023.05.09.540036 — cancer biology — Posted on 2023-10-31
86 Genome-wide evidence of the role of Paf1C in transcription elongation and histone H2B monoubiquitination in Arabidopsis
Blanco, N.; Perez-Alemany, J.; Bourbousse, C.; latrasse, D.; Ait-Mohamed, O.; Benhamed, M.; Barneche, F.; Blazquez, M. A.; Gallego-Bartolome, J.; Alabadi, D.
10.1101/2023.10.27.564443 — plant biology — Posted on 2023-10-31
87 Altered enhancer-promoter interaction leads to MNX1 expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13)
Weichenhan, D.; Riedel, A.; Sollier, E.; Toprak, U. H.; Hey, J.; Breuer, K.; Wierzbinska, J. A.; Touzart, A.; Lutsik, P.; Baehr, M.; Oestlund, A.; Nilsson, C.; Jacobsson, S.; Edler, M.; Waraky, A.; Behrens, Y. L.; Goehring, G.; Schlegelberger, B.; Steinek, C.; Harz, H.; Leonhardt, H.; Dolnik, A.; Reinhardt, D.; Bullinger, L.; Palmqvist, L.; Lipka, D. B.; Plass, C.
10.1101/2023.09.13.557546 — cancer biology — Posted on 2023-10-31
90 Cell-autonomous timing drives the vertebrate segmentation clock's wave pattern
Rohde, L. A.; Bercowsky-Rama, A.; Valentin, G.; Naganathan, S. R.; Desai, R. A.; Strnad, P.; Soroldoni, D.; Oates, A. C.
10.1101/2021.05.29.446196 — developmental biology — Posted on 2023-10-31
91 Water-soluble 4-(dimethylaminomethyl)heliomycin exerts greater antitumor effects than parental heliomycin by targeting the tNOX-SIRT1 axis and apoptosis in oral cancer cells
Islam, A.; Chang, Y.-C.; Chen, X.-C.; Weng, C.-W.; Chen, C.-Y.; Wang, C.-W.; Chen, M.-K.; Tikhomirov, A. S.; Shchekotikhin, A. E.; Chueh, P. J.
10.1101/2023.03.29.534690 — cell biology — Posted on 2023-10-31
93 ACSL4 activity drives TNBC metastasis by positively regulating Histone H3 Acetylation mediated SNAIL expression
Sinha, A.; Saini, K. K.; Tripathi, K.; Khan, M. A.; Satrusal, S. R.; Verma, A.; Mandal, B.; Rai, P.; Meena, S.; Nengroo, M. A.; Singh, M. P.; Bhushan, N. S.; Vasudevan, M.; Singhai, A.; Singh, K.; Mishra, A. K.; Datta, D.
10.1101/2023.10.16.562466 — cancer biology — Posted on 2023-10-31
94 Mitochondrial perturbation of the epithelium causes microbial dysbiosis and unresolved tissue injury in intestinal inflammation
Urbauer, E.; Aguanno, D.; Mindermann, N.; Omer, H.; Metwaly, A.; Khaloian, S.; Reitmeier, S.; Remke, M.; Jarosch, S.; Huber, S.; Busch, D. H.; Stecher, B.; Allez, M.; Steiger, K.; Rath, E.; Haller, D.
10.1101/2023.07.27.549844 — microbiology — Posted on 2023-10-31
95 Recurrent circuits encode visual center-surround computations in the mouse superior colliculus
Cui, P.; Song, K.; Mariatos Metaxas, D.; Isla, A. G.; Femenia, T.; Lazaridis, I.; Meletis, K.; Kumar, A.; Kardamakis, A. A.
10.1101/2023.09.03.556096 — neuroscience — Posted on 2023-10-31
97 Metabolic interactions of a minimal bacterial consortium drive robust nitritation at acidic pH
Ni, G.; Su, Z.; Wang, Y.; Wang, Z.; Wu, M.; Hua, Z.; Hu, S.; Yuan, Z.; Guo, J.; Greening, C.; Zheng, M.
10.1101/2023.10.29.564480 — ecology — Posted on 2023-10-31
100 Cytosolic heme metabolism by alternative localization of heme oxygenase 1 in plant cells
Chen, Y.; Nishimura, K.; Tokizawa, M.; Yamamoto, Y. Y.; Oka, Y.; Matsushita, T.; Hanada, K.; Shirai, K.; Mano, S.; Masuda, T.
10.1101/2023.10.30.564862 — plant biology — Posted on 2023-10-31
103 Exogenous chromosomes reveal how sequence composition drives chromatin assembly, activity, folding and compartmentalization
Chapard, C.; Meneu, L.; Serizay, J.; Westbrook, A.; Routhier, E.; Ruault, M.; Bignaud, A.; Gourgues, G.; Lartigue, C.; Piazza, A.; Taddei, A.; Beckouet, F.; Mozziconacci, J.; Koszul, R.
10.1101/2022.12.21.520625 — genetics — Posted on 2023-10-31
104 Pharmacological enhancement of dopamine neurotransmission does not affect illusory pattern perception
Smith, E.; Michalski, S.; Knauth, K.; Tuzsus, D.; Theis, H.; van Eimeren, T.; Peters, J.
10.1101/2023.10.24.563723 — neuroscience — Posted on 2023-10-31
105 Impact of a tilted coverslip on two-photon and STED microscopy
Le Bourdelles, G.; Mercier, L.; Roos, J.; Bancelin, S.; Nagerl, V.
10.1101/2023.10.26.564142 — neuroscience — Posted on 2023-10-31
110 Multiple transcription factors mediate acclimation of Chlamydomonas to light stress
Wulf, D.; Kruger, F. J.; Klages, L. J.; Viehoever, P.; Jin, E.; Wobbe, L.; Eisenhut, M.; Kruse, O.; Blifernez-Klassen, O.; Braeutigam, A.
10.1101/2023.10.30.564712 — plant biology — Posted on 2023-10-31
111 Substrate evaporation drives collective construction in termites
Facchini, G.; Rathery, A.; Douady, S.; Sillam-Dusses, D.; Perna, A.
10.1101/2023.02.17.528984 — biophysics — Posted on 2023-10-31
112 Hybrid de novo and haplotype resolved genome assembly of Vechur cattle - elucidating genetic variation
Muthusamy, P. V.; Vakayil Mani, R.; Kumari, S.; Kaur, M.; BHASKAR, B.; RAGHAVAN PILLAI, R.; Thankappan, S.; Anilkumar, T. V.; SINGH, N. S.
10.1101/2023.10.27.564393 — genomics — Posted on 2023-10-31
113 Phenotypic stasis with genetic divergence
Mallard, F.; Noble, L.; Guzella, T.; Afonso, B.; Baer, C. F.; Teotonio, H.
10.1101/2022.05.28.493856 — evolutionary biology — Posted on 2023-10-31
114 Epi-microRNA mediated metabolic reprogramming ensures affinity maturation
Nakagawa, R.; Llorian, M.; Varsani-brown, S.; Chakravarty, P.; Camarillo, J. M.; Barry, D.; George, R.; Blackledge, N. P.; Duddy, G.; Kelleher, N. L.; Klose, R. J.; Turner, M.; Calado, D. P.
10.1101/2023.07.31.551250 — immunology — Posted on 2023-10-31
116 Evidence for increased parallel information transmission in human brain networks compared to macaques and mice
Griffa, A.; Mach, M.; Dedelley, J.; Gutierrez-Barragan, D.; Gozzi, A.; Allali, G.; Grandjean, J.; Van De Ville, D.; Amico, E.
10.1101/2022.05.09.491115 — neuroscience — Posted on 2023-10-31
117 Vascular abnormalities in heart and brain are associated with cardiovascular and neurological symptoms in a novel mouse model for Williams syndrome
el Azzouzi, H.; Bosman, L. W.; Kros, L.; van Vliet, N.; Ridwan, Y.; Dijkhuizen, S.; Sabel-Goedknegt, E.; Generowicz, B. S.; Novello, M.; Kretschmann, E.; Snoeren, M.; Broere, D.; Caliandro, R.; Koekkoek, S. K. E.; Kruizinga, P.; Van Dis, V.; Zhou, h.; Yang, H.; Zhou, C.; Van der Pluijm, I.; Essers, J.; De Zeeuw, C. I.
10.1101/2023.10.30.564727 — systems biology — Posted on 2023-10-31
118 Fungal infection alters collective nutritional intake of ant colonies
Csata, E.; Perez-Escudero, A.; Laury, E.; Leitner, H.; Latil, G.; Heinze, J.; Simpson, S.; Cremer, S.; Dussutour, A.
10.1101/2023.10.26.564092 — animal behavior and cognition — Posted on 2023-10-31
119 Joint sequence & chromatin neural networks characterize the differential abilities of Forkhead transcription factors to engage inaccessible chromatin
Arora, S.; Yang, J.; Akiyama, T.; James, D. Q.; Morrissey, A.; Blanda, T.; Badjatia, N.; Lai, W. K. M.; Ko, M. S. H.; Pugh, B. F.; Mahony, S.
10.1101/2023.10.06.561228 — genomics — Posted on 2023-10-31
122 Early human fetal lung atlas reveals the temporal dynamics of epithelial cell plasticity.
Quach, H. T.; Farrell, S.; Kanagarajah, K.; Wu, M.; Xu, X.; Kallurkar, P.; Turinsky, A.; Bear, C.; Ratjen, F.; Goyal, S.; Moraes, T. J.; Wong, A.
10.1101/2023.10.27.564403 — developmental biology — Posted on 2023-10-31
123 Ym1 protein crystals promote type 2 immunity
Heyndrickx, I.; Deswarte, K.; Verstraete, K.; Verschueren, K.; Smole, U.; Aegerter, H.; Dansercoer, A.; Hammad, H.; Savvides, S.; Lambrecht, B.
10.1101/2023.07.03.547463 — immunology — Posted on 2023-10-31
124 Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral and signaling plasticity in vivo.
Ahmed, M. R.; Zheng, C.; Dunning, J. L.; Ahmed, M. S.; Ge, C.; Pair, F. S.; Gurevich, V.; Gurevich, E. V.
10.1101/2023.10.27.564447 — neuroscience — Posted on 2023-10-30
125 Characterization of dynamic patterns of human fetal to neonatal brain asymmetry with deformation-based morphometry
Steger, C.; Moatti, C.; Payette, K.; De Silvestro, A.; Nguyen, T. D.; Coraj, S.; Yakoub, N.; Natalucci, G.; Kottke, R.; Tuura, R.; Knirsch, W.; Jakab, A.
10.1101/2023.10.30.564508 — neuroscience — Posted on 2023-10-31
126 Phylogenomics reveals the deep ocean as an accelerator for evolutionary diversification in anglerfishes
Miller, E. C.; Faucher, R.; Hart, P. B.; Rincon-Sandoval, M.; Santaquiteria, A.; White, W. T.; Baldwin, C. C.; Miya, M.; Betancur-R, R.; Tornabene, L.; Evans, K.; Arcila, D.
10.1101/2023.10.26.564281 — evolutionary biology — Posted on 2023-10-30
132 EphrinB2 knockdown in cervical spinal cord preserves diaphragm innervation in a mutant SOD1 mouse model of ALS
Urban, M. W.; Charsar, B. A.; Heinsinger, N. M.; Markandaiah, S. S.; Sprimont, L.; Zhou, W.; Brown, E. V.; Henderson, N. T.; Thomas, S. J.; Ghosh, B.; Cain, R. E.; Trotti, D.; Pasinelli, P.; Wright, M. C.; Dalva, M. B.; Lepore, A. C.
10.1101/2023.05.10.538887 — neuroscience — Posted on 2023-10-30
133 Fine-grained descending control of steering in walking Drosophila
Yang, H. H.; Brezovec, L. E.; Serratosa Capdevila, L.; Vanderbeck, Q. X.; Adachi, A.; Mann, R. S.; Wilson, R. I.
10.1101/2023.10.15.562426 — neuroscience — Posted on 2023-10-30
139 Functional and structural analysis of a cyclization domain in a cyclic beta-1,2-glucan synthase
Tanaka, N.; Saito, R.; Kobayashi, K.; Nakai, H.; Kamo, S.; Kuramochi, K.; Taguchi, H.; Nakajima, M.; Masaike, T.
10.1101/2023.10.30.564714 — biochemistry — Posted on 2023-10-30
140 Hybrid de novo and haplotype resolved genome assembly of Vechur cattle - elucidating genetic varaiation
Muthusamy, P. V.; Vakayil Mani, R.; Kumari, S.; Kaur, M.; BHASKAR, B.; RAGHAVAN PILLAI, R.; Thankappan, S.; Anilkumar, T. V.; SINGH, N. S.
10.1101/2023.10.27.564393 — genomics — Posted on 2023-10-30
141 Brazilin is a Natural Product Inhibitor of the NLRP3 Inflammasome
McMahon, E. A.; El-Sayed, S.; Green, J. P.; Hoyle, C.; Fitzpatrick, L.; Jones, E.; Corrie, E.; Kelly, R. L.; Challinor, M.; Freeman, S.; Bryce, R. A.; Lawrence, C. B.; Brough, D.; Kasher, P. R.
10.1101/2023.10.30.564348 — molecular biology — Posted on 2023-10-30
142 The mitochondrial mRNA stabilizing protein, SLIRP, regulates skeletal muscle mitochondrial structure and respiration by exercise-recoverable mechanisms
Pham, T. C. P.; Raun, S. H.; Havula, E.; Henriquez-Olguin, C.; Rubalcava-Gracia, D.; Frank, E.; Fritzen, A. M.; Jannig, P. R.; Andersen, N. R.; Kruse, R.; Ali, M.; Halling, J. F.; Ringholm, S.; Hansen, S.; Lemminger, A. K.; Schjerling, P.; Petersen, M. H.; de Almeida, M. E.; Jensen, T. E.; Kiens, B.; Hostrup, M.; Larsen, S.; Ortenblad, N.; Hojlund, K.; Kjaer, M.; Ruas, J. L.; Trifunovic, A.; Wojtaszewski, J. F. P.; Nielsen, J.; Qvortrup, K.; Pilegaard, H.; Richter, E. A.; Sylow, L.
10.1101/2023.10.30.564600 — molecular biology — Posted on 2023-10-30
143 Multi-modal skin atlas associates a multicellular immune-stromal community with altered cornification and T cell expansion in atopic dermatitis
Fiskin, E.; Eraslan, G.; Alora-Palli, M. B.; Leyva-Castillo, J. M.; Kim, S.; Choe, H.; Lareau, C. A.; Lau, H.; Finan, E. P.; Teixeira-Soldano, I.; LaBere, B.; Chu, A.; Woods, B.; Chou, J.; Slyper, M.; Waldman, J.; Islam, S.; Schneider, L.; Phipatanakul, W.; Platt, C.; Rozenblatt-Rosen, O.; Delorey, T. M.; Deguine, J.; Smith, G. P.; Geha, R. S.; Regev, A.; Xavier, R. J.
10.1101/2023.10.29.563503 — molecular biology — Posted on 2023-10-30
144 The mtDNA-derived lncMtDloop promotes mitochondrial homeostasis maintenance and implications in AD
Xiong, W.; Xu, K.; Sun, J. K.-L.; Liu, S.; Zhao, B.; Shi, J.; Herrup, K.; Chow, H.-M.; Lu, L.; Li, J.
10.1101/2023.10.30.564670 — molecular biology — Posted on 2023-10-30
145 Structural insight into rabies virus neutralization revealed by an engineered antibody scaffold
Kedari, A.; Iheozor-Ejiofor, R. P.; Levanov, L.; Saksela, K.; Vapalahti, O.; Rissanen, I.
10.1101/2023.10.30.564668 — molecular biology — Posted on 2023-10-30
146 IGF2 Peptide-Based LYTACs for Targeted Degradation of Extracellular and Transmembrane Proteins
Mikitiuk, M.; Barczynski, J.; Bielski, P.; Arciniega, M.; Błaszkiewicz, U.; Hec, A.; Lipinska, A. D.; Rychłowski, M.; Holak, T. A.; Sitar, T.
10.1101/2023.10.30.563730 — molecular biology — Posted on 2023-10-30
150 Nucleoprotein reassortment enhanced transmissibility of H3 1990.4.a clade influenza A virus in swine
Thomas, M. N.; Ciacci Zanella, G.; Cowan, B.; Caceres, C. J.; Rajao, D.; Perez, D. R.; Gauger, P. C.; Baker, A. L.; Anderson, T. K.
10.1101/2023.10.30.564250 — microbiology — Posted on 2023-10-30
151 Evidence for circulation of Rift Valley fever virus in wildlife and domestic animals in a forest environment in Gabon, Central Africa
Becquart, P.; Bohou Kombila, L.; Mebaley, T. N.; Paupy, C.; Garcia, D.; Nesi, N.; Olive, M.-M.; Vanhomwegen, J.; Boundenga, L.; Mombo, I. M.; Piro-Megy, C.; Fritz, M.; Lenguiya, L. H.; Gouilh, M. A.; Leroy, E. M.; N'Dilimabaka, N.; Cetre-Sossah, C.; Maganga, G. D.
10.1101/2023.10.30.564676 — microbiology — Posted on 2023-10-30
152 Multi-site identification and generalization of clusters of walking impairment in individuals with chronic stroke and neurotypical controls
Sanchez, N.; Schweighofer, N.; Mulroy, S.; Roemmich, R. T.; Kesar, T. M.; Torres-Oviedo, G.; Fisher, B. E.; Finley, J.; Winstein, C. J.
10.1101/2023.05.11.540385 — neuroscience — Posted on 2023-10-30
155 Analysis of uveal melanoma scRNA sequencing data identifies neoplastic-immune hybrid cells that exhibit metastatic potential
Anderson, A. N.; Conley, P.; Klocke, C. D.; Sengupta, S. K.; Robinson, T. L.; Fan, Y.; Jones, J. A.; Gibbs, S. L.; Skalet, A. H.; Wu, G.; Wong, M. H.
10.1101/2023.10.24.563815 — cancer biology — Posted on 2023-10-30
158 Colloidal aggregation confounds cell-based Covid-19 antiviral screens
Glenn, I. S.; Hall, L. N.; Khalid, M. M.; Ott, M.; Shoichet, B. K.
10.1101/2023.10.27.564435 — biochemistry — Posted on 2023-10-30
159 The LexA-RecA* structure reveals a lock-and-key mechanism for SOS activation
Cory, M. B.; Li, A.; Hurley, C. M.; Carman, P. J.; Pumroy, R. A.; Hostetler, Z. M.; Venkatesh, Y.; Gupta, K. B.; Petersson, E. J.; Kohli, R. M.
10.1101/2023.10.30.564768 — biochemistry — Posted on 2023-10-30
160 Copy number variation and elevated genetic diversity at immune trait loci in Atlantic and Pacific herring
Mohamadnejad Sangdehi, F.; Jamsandekar, M. S.; Enbody, E. D.; Pettersson, M. E.; Andersson, L.
10.1101/2023.10.26.564141 — genomics — Posted on 2023-10-30
166 Characterization of Unique Pathological Features of COVID-Associated Coagulopathy: Studies with AC70 hACE2 Transgenic Mice Highly Permissive to SARS-CoV-2 Infection
Drelich, A. K.; Rayavara, K.; Hsu, J.; Saenkham-Huntsinger, P.; Judy, B. M.; Tat, V.; Ksiazek, T. G.; Peng, B.-H.; Tseng, C.-T. K.
10.1101/2023.10.30.564680 — microbiology — Posted on 2023-10-30
169 Peptide-mimetic treatment of Pseudomonas aeruginosa in a mouse model of respiratory infection
Moule, M. G.; Benjamin, A. B.; Burger, M. L.; Herlan, C.; Lebedev, M.; Lin, J. S.; Koster, K. J.; Wavare, N.; Adams, L. G.; Bräse, S.; Barron, A. E.; Cirillo, J. D.
10.1101/2023.10.30.564794 — microbiology — Posted on 2023-10-30
170 Maternal immunization with distinct influenza vaccine platforms elicits unique antibody profiles that impact the protection of offspring
Vazquez-Pagan, A.; Roubidoux, E. K.; Cherry, S.; Livingston, B.; Bub, T.; Lazure, L.; Sharp, B.; Confer, T.; Brigleb, P. H.; Honce, R.; Whitt, K. T.; Johnson, M.; Meliopoulos, V. A.; Schultz-Cherry, S.
10.1101/2023.10.30.564827 — microbiology — Posted on 2023-10-30
171 A virally encoded high resolution screen of cytomegalovirus host dependencies
Finkel, Y.; Nachshon, A.; Aharon, E.; Arazi, T.; Simonovsky, E.; Dobesova, M.; Gluck, A.; Fisher, T.; Stanton, R. J.; Schwartz, M.; Stern-Ginossar, N.
10.1101/2023.10.30.564793 — microbiology — Posted on 2023-10-30
173 Cyanobacteria newly isolated from marine volcanic seeps display rapid sinking and robust, high density growth
Schubert, M. G.; Tang, T.-C.; Goodchild-Michelman, I. M.; Ryon, K. A.; Henriksen, J. R.; Chavkin, T.; Wu, Y.; Miettinen, T. P.; Van Wychen, S.; Dahlin, L.; Spatafora, D.; Turco, G.; Guarnieri, M.; Manalis, S. R.; Kowitz, J.; Dhir, R.; Quatrini, P.; Mason, C. E.; Church, G. M.; Milazzo, M.; Tierney, B. T.
10.1101/2023.10.30.564770 — microbiology — Posted on 2023-10-30
174 Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping
Netskar, H. K.; Pfefferle, A.; Goodridge, J. P.; Sohlberg, E.; Dufva, O.; Teichmann, S.; Clancy, T.; horowitz, a.; Malmberg, K.-J.
10.1101/2023.10.26.564050 — immunology — Posted on 2023-10-30
175 NK cell-monocyte crosstalk underlies NK cell activation in severe COVID-19
Lee, M. J.; de los Rios Kobara, I.; Barnard, T. R.; Vales Torres, X.; Tobin, N. H.; Ferbas, K. G.; Rimoin, A. W. J.; Yang, O. O.; Aldrovandi, G. M.; Wilk, A. J.; Fulcher, J.; Blish, C. A.
10.1101/2023.10.27.564440 — immunology — Posted on 2023-10-30
176 Is Rapid Eye Movement Sleep a Paradoxical State of Sleep?
Boscher, F.; Jumel, K.; Dvorakova, T.; Gentet, L. J.; Urbain, N.
10.1101/2023.10.26.564196 — neuroscience — Posted on 2023-10-30
177 Species Composition and Distribution of Anopheles gambiae Complex Circulating in Kinshasa
Zanga, J.; Metelo, E.; Mvuama, N.; Nsabatien, V. N.; Mvudi, V.; Banzulu, D.; Mansiangi, O.; Bamba, M.; Basosila, N.; Agossa, F.; Wumba, R.
10.1101/2023.10.26.564181 — zoology — Posted on 2023-10-30
182 Somatic mutation detection workflow validity distinctly influences clinical decision.
Chien, P.-M.; Cheng, C.; Yuan, T.-H.; Wang, Y.-B.; Chen, P.-L.; Chen, C.-Y.; Huang, J.-H.; Hsu, J. S.
10.1101/2023.10.26.562640 — bioinformatics — Posted on 2023-10-30
184 Parkin R274W mutation affects muscle physiology via the PARIS-PGC-1α pathway
Sevegnani, M.; Lama, A.; Girardi, F.; Hess, M. W.; Castelo, M. P.; Pichler, I.; Biressi, S.; Piccoli, G.
10.1101/2023.10.26.564192 — animal behavior and cognition — Posted on 2023-10-30
185 Aggression: A gut reaction? The effects of gut microbiome on aggression
Uzan-Yulzari, A.; Turjeman, S.; Getselter, D.; Rautava, S.; Isolauri, E.; Khatib, S.; Elliott, E.; Koren, O.
10.1101/2023.10.26.564110 — animal behavior and cognition — Posted on 2023-10-30
186 Fungal infection alters collective nutritional intake of ant colonies
Csata, E.; Perez-Escudero, A.; Laury, E.; Leitner, H.; Latil, G.; Heinze, J.; Simpson, S.; Cremer, S.; Dussutour, A.
10.1101/2023.10.26.564092 — animal behavior and cognition — Posted on 2023-10-30
188 Neoadjuvant Therapy Differentially Remodels Carcinoma and Tumor Microenvironment in Pancreatic Ductal Adenocarcinoma: Insights from Spatially Resolved Transcriptomics
Zhang, X.; Liu, Y.-Z.; Lan, R.; Liu, Y.; Pillarisetty, V. G.; Li, D.; Zhao, C. L.; Sarkar, S.; Liu, W.; Hanna, I.; Gupta, M.; Hajdu, C.; Melamed, J.; Widmer, J.; Allendorf, J.
10.1101/2023.10.26.564099 — genomics — Posted on 2023-10-30
192 Eosinophils are an endogenous source of IL-4 during filarial infections and contribute to the development of an optimal T helper 2 response
Guth, C.; Schumacher, P. P.; Vijayakumar, A.; Borgmann, H.; Balles, H.; Koschel, M.; Risch, F.; Lenz, B.; Hoerauf, A.; Hubner, M. P.; Ajendra, J.
10.1101/2023.10.26.564180 — immunology — Posted on 2023-10-30
193 IL-27 maintains cytotoxic Ly6C+ gamma delta T cells that arise from immature precursors
Wiesheu, R.; Edwards, S. C.; Hedley, A.; Tosolini, M.; Fares da Silva, M. G. F.; Sumaria, N.; Optaczy, Y.; Hill, D. G.; Hayes, A. J.; Hay, J.; Kilbey, A.; Michie, A. M.; Graham, G.; Manoharan, A.; Halsey, C.; Jones, G. W.; Blyth, K.; Fournie, J.-J.; Pennington, D.; Bekiaris, V.; Coffelt, S. B.
10.1101/2023.10.26.564114 — immunology — Posted on 2023-10-30
198 Consolidation of sensorimotor adaptation depends both on the passage of time and sleep
Solano, A.; Lerner, G.; Griffa, G.; Deleglise, A.; Caffaro, P.; Riquelme, L.; Perez-Chada, D.; Della-Maggiore, V.
10.1101/2023.10.26.564031 — neuroscience — Posted on 2023-10-30
203 Single-nucleus RNA sequencing provides insights into the GL261-GSC syngeneic mouse model of glioblastoma
Garcia-Vicente, L.; Borja, M.; Tran, V.; Alvarez-Vazquez, A.; Flores-Hernandez, R.; Granados, A.; McGeever, A.; Kim, Y.-J.; Dorman, L.; Detweiler, A.; Mekonen, H.; Paul, S.; Pisco, A. O.; Neff, N. F.; Tabernero, A.
10.1101/2023.10.26.564166 — neuroscience — Posted on 2023-10-30
204 Specificity, synergy, and mechanisms of splice-modifying drugs
Ishigami, Y.; Wong, M. S.; Marti-Gomez, C.; Ayaz, A.; Kooshkbaghi, M.; Hanson, S.; McCandlish, D. M.; Krainer, A. R.; Kinney, J. B.
10.1101/2022.12.30.522303 — biophysics — Posted on 2023-10-30
207 Semantic harmonization of Alzheimer's disease datasets using AD-Mapper
Wegner, P.; Balabin, H.; Ay, M. C.; Bauermeister, S.; Killin, L.; Gallacher, J.; Hofmann-Apitius, M.; Salimi, Y.
10.1101/2023.10.26.564134 — bioinformatics — Posted on 2023-10-30
208 Cartography of the developability landscapes of native and human-engineered antibodies
Bashour, H.; Smorodina, E.; Pariset, M.; Zhong, J.; Akbar, R.; Chernigovskaya, M.; Le Quy, K.; Snapkov, I.; Rawat, P.; Krawczyk, K.; Sandve, G. K.; Gutierrez-Marcos, J.; Nakhaee-Zadeh Gutierrez, D.; Andersen, J. T.; Greiff, V.
10.1101/2023.10.26.563958 — bioinformatics — Posted on 2023-10-30
216 A time-resolved multi-omics atlas of transcriptional regulation in response to high-altitude hypoxia across whole-body tissues
Yan, Z.; Yang, J.; Wei, W.-T.; Zhou, M.-L.; Mo, D.-X.; Wan, X.; Ma, R.; Wu, M.-M.; Huang, J.-H.; Liu, Y.-J.; Lv, F.-H.; Li, M.-H.
10.1101/2023.10.25.563964 — genetics — Posted on 2023-10-30
220 A large-scale volumetric correlated light and electron microscopy study localizes Alzheimer's disease-related molecules in the hippocampus
Han, X.; Li, P. H.; Wang, S.; Sanchez, M.; Aggarwal, S.; Blakely, T.; Schalek, R.; Meirovitch, Y.; Lin, Z.; Wu, Y.; Aly, F.; Bay, S.; Delatour, B.; Lafaye, P.; Pfister, H.; Wei, D.; Jain, V.; Ploegh, H.; Lichtman, J.
10.1101/2023.10.24.563674 — neuroscience — Posted on 2023-10-30
223 Driving and suppressing the human language network using large language models
Tuckute, G.; Sathe, A.; Srikant, S.; Taliaferro, M.; Wang, M.; Schrimpf, M.; Kay, K.; Fedorenko, E.
10.1101/2023.04.16.537080 — neuroscience — Posted on 2023-10-30
225 Dorsal peduncular cortex activity modulates affective behavior and fear extinction in mice
Botterill, J. J.; Khlaifia, A.; Appings, R.; Wilkin, J.; Violi, F.; Premachandran, H.; Cruz-Sanchez, A.; Canella, A. E.; Patel, A.; Zaidi, S. D.; Arruda-Carvalho, M.
10.1101/2023.04.25.538301 — neuroscience — Posted on 2023-10-30
227 Modulating Subjective Pain Perception with Decoded MNI-space Neurofeedback
Berman, T.; Cushing, C.; Manuel, S.; Vachon-Presseau, E.; Cortese, A.; Kawato, M.; Woo, C.-W.; Wager, T.; Lau, H.; Roy, M.; Taschereau-Dumouchel, V.
10.1101/2023.10.25.563972 — neuroscience — Posted on 2023-10-30
228 Histone deacetylase inhibition mitigates cognitive deficits and astrocyte dysfunction induced by Ab oligomers
Morgado, J.; Diniz, L. P.; Araujo, A. P. B.; Antonio, L. M. d. S.; Araujo, H. P. M.; Pinheiro, P. d. S. M.; Sagrillo, F. S.; Cesar, G. V.; Ferreira, S. T.; Figueiredo, C. P.; Fraga, C. A. M.; GOMES, F. C. A.
10.1101/2023.10.25.564038 — neuroscience — Posted on 2023-10-30
230 Deep brain stimulation device-specific artefacts in MEG recordings
Bahners, B. H.; Lofredi, R.; Sander, T.; Schnitzler, A.; Kuhn, A. A.; Florin, E.
10.1101/2023.10.25.563956 — neuroscience — Posted on 2023-10-30
231 AlphaFold2 captures the conformational landscape of the HAMP signaling domain
Winski, A.; Ludwiczak, J.; Orlowska, M.; Madaj, R.; Kaminski, K.; Dunin-Horkawicz, S.
10.1101/2023.05.23.541686 — bioinformatics — Posted on 2023-10-30
235 Molecular definition of distinct active zone protein machineries for Ca2+ channel clustering and synaptic vesicle priming
Emperador-Melero, J.; Andersen, J. W.; Metzbower, S. R.; Levy, A. D.; Dharmasri, P. A.; de Nola, G.; Blanpied, T. A.; Kaeser, P. S.
10.1101/2023.10.27.564439 — neuroscience — Posted on 2023-10-30
237 Recursive self-embedded vocal motifs in wild orangutans
Lameira, A. R.; Hardus, M. E.; Ravignani, A.; Raimondi, T.; Gamba, M.
10.1101/2023.04.14.536836 — animal behavior and cognition — Posted on 2023-10-30
238 Visual mental imagery in typical imagers and in aphantasia: A millimeter-scale 7-T fMRI study
Liu, J.; Zhan, M.; Hajhajate, D.; Spagna, A.; Dehaene, S.; Cohen, L.; Bartolomeo, P.
10.1101/2023.06.14.544909 — neuroscience — Posted on 2023-10-30
241 Impairment of hippocampal astrocyte-mediated striatal dopamine release and locomotion in Alzheimer's disease
Tournier, B. B.; Ceyzeriat, K.; Badina, A.; Gloria, Y.; Fall, A.; Amosse, Q.; Tsartsalis, S.; Millet, P.
10.1101/2023.10.29.564619 — neuroscience — Posted on 2023-10-30
243 The Evolution of Democratic Peace in Animal Societies
Hunt, K. L.; Patel, M.; Croft, D. P.; Franks, D. W.; Green, P. A.; Thompson, F. J.; Johnstone, R. A.; Cant, M. A.; Sankey, D. W. E.
10.1101/2023.02.14.528470 — evolutionary biology — Posted on 2023-10-30
244 WITHDRAWN: Demographic and ecological drivers of infectome diversity in companion cats
Sun, Y.; Xing, J.; Xu, S.; Li, Y.; Gao, H.; Cheng, S.; Dong, J.; Zhang, T.; Lu, G.; Baele, G.; Zhang, G.
10.1101/2023.09.01.555855 — evolutionary biology — Posted on 2023-10-30
245 Longitudinal Survey of Astrovirus infection in different bat species in Zimbabwe: Evidence of high genetic Astrovirus diversity
Chidoti, V.; De Nys, H.; Abdi, M.; Mashura, G.; Pinarello, V.; Chiweshe, N.; Matope, G.; Guerrini, L.; Pfulenyi, D.; Cappelle, J.; Mwandiringana, E.; Misse, D.; Elizabeth, G.; Bourgarel, M.; Liegeois, F.
10.1101/2023.04.14.536987 — molecular biology — Posted on 2023-10-30
246 The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation
Bastidas, R. J.; Kedzior, M.; Davidson, R. K.; Walsh, S. C.; Dolat, L.; Sixt, B. S.; Pruneda, J. N.; Coers, J.; Valdivia, R. H.
10.1101/2023.02.28.530337 — microbiology — Posted on 2023-10-30
252 Flexible and abstract neural representations of abstract structural knowledge
Mark, S.; Baram, A.; Schwartenbeck, P.; Hahamy, A.; Samborska, V.; Behrens, T. E. J.
10.1101/2023.08.31.555760 — neuroscience — Posted on 2023-10-30
258 Conifers concentrate large numbers of NLR immune receptor genes on one chromosome
Woudstra, Y.; Tumas, H.; Van Ghelder, C.; Hung, T. H.; Ilska, J. J.; Girardi, S.; A'Hara, S.; McLean, P.; Cottrell, J.; Bohlmann, J.; Bousquet, J.; Birol, I.; Woolliams, J. A.; MacKay, J. J.
10.1101/2023.10.20.563305 — genomics — Posted on 2023-10-30
259 Target complementarity in cnidarians supports a common origin for animal and plant microRNAs
Admoni, Y.; Fridrich, A.; Razin, T.; Salinas-Saavedra, M.; Rabani, M.; Frank, U.; Moran, Y.
10.1101/2023.01.08.523153 — evolutionary biology — Posted on 2023-10-30
260 Pervasive relaxed selection on spermatogenesis genes coincident with the evolution of polygyny in gorillas
Bowman, J. D.; Silva, N.; Schüftan, E.; Almeida, J. M.; Brattig-Correia, R.; Oliveira, R. A.; Tüttelmann, F.; Enard, D.; Navarro-Costa, P.; Lynch, V. J.
10.1101/2023.10.27.564379 — evolutionary biology — Posted on 2023-10-30
262 Cell type-specific contributions to a persistent aggressive internal state in female Drosophila
Chiu, H.; Robie, A. A.; Branson, K. M.; Vippa, T.; Epstein, S.; Rubin, G. M.; Anderson, D. J.; Schretter, C. E.
10.1101/2023.06.07.543722 — neuroscience — Posted on 2023-10-30
264 Induced neural phase precession through exogeneous electric fields
Wischnewski, M.; Tran, H.; Zhao, Z.; Shirinpour, S.; Haigh, Z. J.; Rotteveel, J.; Perera, N. D.; Alekseichuk, I.; Zimmermann, J.; Opitz, A.
10.1101/2023.03.31.535073 — neuroscience — Posted on 2023-10-30
265 Longitudinal single-cell data informs deterministic modelling of inflammatory bowel disease
Kilian, C.; Ulrich, H.; Zouboulis, V.; Sprezyna, P.; Schreiber, J.; Landsberger, T.; Büttner, M.; Biton, M.; Villablanca, E. J.; Huber, S.; Adlung, L.
10.1101/2023.10.27.561846 — systems biology — Posted on 2023-10-30
271 Reliability of high-quantity human brain organoids for modeling microcephaly, glioma invasion, and drug screening
Ramani, A.; Pasquini, G.; Gerkau, N.; Vinchure, O. S.; Gabriel, E.; Rothenaigner, I.; Lin, S.; Altinisk, N.; Rathinam, D.; Mirsaidi, A.; Goureau, O.; Ricci-Vitiani, L.; Q. d'alessandris, G.; Pallini, R.; Wollnik, B.; Muotri, A.; Jurisch-Yaksi, N.; Rose, C. R.; Busskamp, V.; Hadian, K.; Gopalakrishnan, J.
10.1101/2023.10.29.564523 — cell biology — Posted on 2023-10-30
274 ABIN1 is a negative regulator of effector functions in cytotoxic T cells
Janusova, S.; Paprckova, D.; Michalik, J.; Uleri, V.; Drobek, A.; Salyova, E.; Chorfi, L.; Neuwirth, A.; Prochazka, J.; Sedlacek, R.; Draber, P.; Stepanek, O.
10.1101/2023.10.25.563918 — immunology — Posted on 2023-10-30
275 Power and reproducibility in the external validation of brain-phenotype predictions
Rosenblatt, M.; Tejavibulya, L.; Camp, C. C.; Jiang, R.; Westwater, M. L.; Noble, S.; Scheinost, D.
10.1101/2023.10.25.563971 — neuroscience — Posted on 2023-10-30
276 Competitive specific anchorage of molecules onto surfaces: quantitative control of grafting densities and contamination by free anchors
Kirichuk, O.; Srimasorn, S.; Zhang, X.; Roberts, A. R. E.; Coche-Guerente, L.; Kwok, J. C. F.; Bureau, L.; Debarre, D.; Richter, R. P.
10.1101/2023.06.27.546772 — biophysics — Posted on 2023-10-30
278 Prolonged delays in human microbiota transmission after a controlled antibiotic perturbation
Xue, K. S.; Walton, S. J.; Goldman, D. A.; Morrison, M. L.; Verster, A. J.; Parrott, A. B.; Yu, F. B.; Neff, N.; Rosenberg, N. A.; Ross, B. D.; Petrov, D.; Huang, K. C.; Good, B. H.; Relman, D.
10.1101/2023.09.26.559480 — microbiology — Posted on 2023-10-30
279 Activity-regulated micro-exon splicing programs underlie late-onset plasticity at the axon initial segment
Darwish, M.; Suzuki, S.; Ogawa, Y.; Takase, A.; Tanaka, M.; Iijima, Y.; Sato, Y.; Suzuki, M.; Kanegae, Y.; Okada, C.; Takana, M.; Okano, H. J.; Kuba, H.; Iijima, T.
10.1101/2023.10.29.564567 — neuroscience — Posted on 2023-10-30
280 Social buffering switches fear to safety encoding by oxytocin recruitment of central amygdala "buffer neurons"
Hegoburu, C.; Tang, Y.; Niu, R.; Ghosh, S.; Triana del Rio, R.; Salgado, I.; Abatis, m.; Caseiro, D. A. M.; grundschober, c.; STOOP, R.
10.1101/2023.10.29.563530 — neuroscience — Posted on 2023-10-30
283 Improving the Circularization Efficiency, Stability and Translatability of Circular RNA by circDesign
Xu, C.; Zhang, L.; Wang, W.; Tang, Y.; Wang, Q.; An, J.; Xu, H.; Ge, Y.; Zhu, H.; Wang, H.; Li, B.; Wang, X.; Qiu, X.; Shen, M.; Chen, G.; Shen, H.; Huang, L.; Li, H.
10.1101/2023.07.09.548293 — bioengineering — Posted on 2023-10-29
287 Trabid patient mutations impede the axonal trafficking of adenomatous polyposis coli to disrupt neurite growth
Frank, D.; Bergamasco, M.; Mlodzianoski, M.; Kueh, A.; Tsui, E.; Hall, C.; Kastrappis, G.; Voss, A. K.; McLean, C.; Faux, M. C.; Rogers, K.; Tran, B.; Vincan, E.; Komander, D.; Dewson, G.; Tran, H.
10.1101/2023.07.17.549243 — cell biology — Posted on 2023-10-29
290 Quantifying the performance benefits of middle distance running super spikes
Bertschy, M.; Rodrigo Carranza, V.; Wilkie, E. W. C.; Healey, L. A.; Noble, J.; Albert, W. J.; Hoogkamer, W.
10.1101/2023.10.25.564056 — physiology — Posted on 2023-10-29
297 Phase-changing citrate macromolecule combats oxidative pancreatic islet damage, enables islet engraftment and function in the omentum
Burke, J. A.; Zhang, X.; Zhu, Y.; Rios, P. D.; Joshi, I.; Lopez, D.; Nasir, H.; Roberts, S.; Rodriguez, Q.; McGarrigle, J.; Cook, D.; Oberholzer, J.; Luo, X.; Ameer, G. A.
10.1101/2023.10.25.564034 — bioengineering — Posted on 2023-10-29
300 Evaluating ChatGPT as an Agent for Providing Genetic Education
Walton, N.; Graceffo, S.; Sutherland, N.; Kozel, B.; Danford, C.; McGrath, S.
10.1101/2023.10.25.564074 — genomics — Posted on 2023-10-29
301 The GIAB genomic stratifications resource for human reference genomes
Dwarshuis, N.; Kalra, D.; McDaniel, J.; Sanio, P.; Alvarez Jerez, P.; Jadhav, B.; Huang, W.; Mondal, R.; Busby, B.; Olson, N. D.; Sedlazeck, F. J.; Wagner, J.; Majidian, S.; Zook, J. M.
10.1101/2023.10.27.563846 — genomics — Posted on 2023-10-29
304 Telomere protein arrays stall DNA loop extrusion by condensin
Analikwu, B. T.; Deshayes, A.; van der Torre, J.; Guerin, T.; Katan, A. J.; Beneut, C.; Barth, R.; Phipps, J.; Scolari, V.; Veaute, X.; Barrington, C.; Busso, D.; Uhlmann, F.; Dubrana, K.; Mattarocci, S.; Dekker, C.; Marcand, S.
10.1101/2023.10.29.564563 — molecular biology — Posted on 2023-10-29
305 Noise-induced changes in rat head stability and orientation correlate with dysfunction of otolith irregular afferents
Niwa, M.; Bauer, D.; Anderson, M.; Keller, K.; Kanicki, A.; Altschuler, R.; Stewart, C. E.; King, W. M.
10.1101/2023.10.26.563800 — neuroscience — Posted on 2023-10-29
306 Multimodal fusion of brain signals for robust prediction of psychosis transition
Reinen, J. M.; Polosecki, P.; Castro, E.; Corcoran, C. M.; Cecchi, G.; Colibazzi, T.
10.1101/2023.10.25.563602 — neuroscience — Posted on 2023-10-29
307 Systematic exploration of bacterial form I rubisco maximal carboxylation rates
de Pins, B.; Greenspoon, L.; Bar-On, Y. M.; Shamshoum, M.; Ben-Nissan, R.; Milshtein, E.; Davidi, D.; Sharon, I.; Mueller-Cajar, O.; Noor, E.; Milo, R.
10.1101/2023.07.27.550689 — systems biology — Posted on 2023-10-29
309 Integration of QTL and transcriptome approaches for the identification of genes involved in tomato response to nitrogen deficiency
Desaint, H.; Hereil, A.; Belinchon-Moreno, J.; Carretero, Y.; Pelpoir, E.; Pascal, M.; Brault, M.; Dumont, D.; Lecompte, F.; Laugier, P.; Duboscq, R.; Bitton, F.; Grumic, M.; Giraud, C.; Ferrante, P.; Giuliano, G.; Sunseri, F.; Causse, M.
10.1101/2023.10.26.564109 — plant biology — Posted on 2023-10-29
313 Structure-Based Discovery of a NPFF1R Antagonist with Analgesic Activity
Bender, B. J.; Pickett, J. E.; Braz, J.; Kang, H. J.; Gahbauer, S.; Bhardwaj, K.; Rodriguez-Rosado, S.; Liu, Y.; Jain, M.; Basbaum, A.; Roth, B. L.; Shoichet, B. K.
10.1101/2023.10.25.564029 — pharmacology and toxicology — Posted on 2023-10-29
314 ZNF865 Regulates Senescence and Cell Cycle for Applications to Cell Engineering and Gene Therapy
Levis, H.; Lewis, C.; Stockham, E.; Weston, J. D.; Lawal, A.; Lawrence, B.; Gullbrand, S. E.; Bowles, R. D.
10.1101/2023.10.25.563801 — bioengineering — Posted on 2023-10-29
315 Replacement of tibialis cranialis tendon with polyester, silicone-coated artificial tendon preserves biomechanical function in rabbits
Easton, K. L.; Hatch, C.; Stephens, K.; Marler, D.; Fidelis, O. P.; Sun, X.; Bowers, K. M.; Billings, C.; Greenacre, C. B.; Anderson, D. E.; Crouch, D. L.
10.1101/2023.10.25.563771 — bioengineering — Posted on 2023-10-29
317 EV-Elute: a universal platform for enrichment of functional surface marker-defined extracellular vesicle subpopulations
de Voogt, W. S.; Frunt, R.; Leandro, R. M.; Triesscheijn, C. S.; Monica, B.; Paspali, I.; Tielemans, M.; Francois, J. J.; Seinen, C. W.; de Jong, O. G.; Kooijmans, S. A.
10.1101/2023.10.25.563755 — bioengineering — Posted on 2023-10-29
318 The N-terminal region of DNMT3A combines multiple chromatin reading motifs to guide recruitment.
Wapenaar, H.; Clifford, G.; Rolls, W.; Burdett, H.; Zhang, Y.; Deak, G.; Zou, J.; Taylor, M. R.; Mills, J.; Watson, J. A.; Kumar, D.; Das, A.; Valsakumar, D.; Bramham, J.; Voigt, P.; Wilson, M. D.
10.1101/2023.10.29.564595 — biochemistry — Posted on 2023-10-29
319 Zinc finger domains bind low-complexity domain polymers
Iguchi, N.; Isozumi, N.; Hattori, Y.; Imamura, T.; So, M.; Nanaura, H.; Kiriyama, T.; Eura, N.; Yamaoka, M.; Nakanishi, M.; Mori, M.; Ohki, S.; Kumeta, H.; Koga, H.; Watabe, M.; Mabuchi, T.; Kanemura, S.; Okumura, M.; Yoshizawa, T.; Ota, I.; Suzuki, N.; Aoki, M.; Yamashiro, Y.; Saio, T.; Sugie, K.; Mori, E.
10.1101/2023.10.29.564599 — biochemistry — Posted on 2023-10-29
320 The roles of DDR2 and substrate stiffness on cancer cell transcriptome and proliferation
Vessella, T.; Xiang, S.; Wen, Q.; Zhou, S.; Rozen, E.; Shohet, J.; Stilwell, M.; Xiao, C.
10.1101/2023.10.29.564363 — biochemistry — Posted on 2023-10-29
323 Productive foraging sites enhance maternal health and impact offspring fitness in a capital breeding species
Fouda, L.; Negus, S. R. B.; Lockley, E. C.; Fairweather, K.; Lopes, A.; Lopes, A.; Correia, S. M.; Taxonera, A.; Schofield, G.; Eizaguirre, C.
10.1101/2023.10.27.563439 — ecology — Posted on 2023-10-29
329 Untangling the Role of Pathobionts from Bacteroides Species in Inflammatory Bowel Diseases
Shan, Y.; Lake, J.; Cham, C. M.; Zhu, M.; Kaur, D.; Ringus, D.; Fei, N.; Weber, C. R.; Spedale, M.; Theriault, B.; Dalal, S.; Rubin, D. T.; Fiebig, A.; Crosson, S.; Lolans, K.; Comstock, L.; Eren, A. M.; Basu, A.; Pott, S.; Sogin, M.; Liu, C.; Chang, E. B.
10.1101/2023.10.29.564605 — microbiology — Posted on 2023-10-29
330 Aberrant N-glycosylation in pathogenic variants of adenosine deaminase 2 underlying human ADA2 deficiency
Ehlers, L.; Hombrouck, A.; Wouters, M.; Pillay, B.; Delafontaine, S.; Bucciol, G.; Baggio, M.; Dzhus, M.; Jacquemyn, M.; De Somer, L.; Schrijvers, R.; Vanderschueren, S.; Cassiman, D.; Kirchner, M.; Mertins, P.; Kallinich, T.; Daelemans, D.; Agostinis, P.; Moens, L.; Meyts, I.
10.1101/2023.10.25.564037 — immunology — Posted on 2023-10-29
333 Fibrinogen and complement factor H: The two crucial markers of Parkinson's disease with cognitive impairment
Naskar, A.; Sachin, M.; Sengupta, S.; Bhadrachallam, P.; Hegde, S.; Yadav, R.; Pal, P. K.; Alladi, P. A.
10.1101/2023.10.25.563920 — neuroscience — Posted on 2023-10-29
337 Multi-scale photocatalytic proximity labeling reveals cell surface neighbors on and between cells
Lin, Z.; Schaefer, K.; Lui, I.; Yao, Z.; Fossati, A. A.; Swaney, D. L.; Palar, A.; Sali, A.; Wells, J. A.
10.1101/2023.10.28.564055 — biochemistry — Posted on 2023-10-29
338 SMARTdb: An Integrated Database for Exploring Single-cell Multi-omics Data of Reproductive Medicine
Liu, Z.; Yuan, Z.; Guo, Y.; Wang, R.; Guan, Y.; Wang, Z.; Chen, Y.; Wang, T.; Jiang, M.; Bian, S.
10.1101/2023.09.10.556986 — genomics — Posted on 2023-10-29
339 ProA and ProB repeat sequences shape genome organization, and enhancers open domains
Bonnet, K. A.; Hulo, N.; Mourad, R.; Ewing, A.; Croce, O.; Naville, M.; Vassetzky, N.; Gilson, E.; Picard, D.; Fourel, G.
10.1101/2023.10.27.564043 — genetics — Posted on 2023-10-29
340 Assessing the impact of 20th century internal migrations on the genetic structure of Estonia
Kuznetsov, I. A.; Estonian Biobank Research Team, ; Metspalu, M.; Vainik, U.; Pagani, L.; Montinaro, F.; Pankratov, V.
10.1101/2023.10.25.564036 — genetics — Posted on 2023-10-29
341 Global abundance patterns, diversity, and ecology of Patescibacteria in wastewater treatment plants
Wagner, M.; Hu, H.; Kristensen, J. M.; Pjevac, P.; Kitzinger, K.; Herbold, C. W.; Hausmann, B.; Dueholm, M. K. D.; Nielsen, P. H.
10.1101/2023.10.25.562895 — ecology — Posted on 2023-10-29
347 Comprehensive analysis of cellular specializations that initiate parallel auditory processing pathways in mice
Jing, J.; Hu, M.; Ngodup, T.; Ma, Q.; Lau, S. N. N.; Ljungberg, C.; McGinley, M. J.; Trussell, L. O.; Jiang, X.
10.1101/2023.05.15.539065 — neuroscience — Posted on 2023-10-29
350 Rosace: a robust deep mutational scanning analysis framework employing position and mean-variance shrinkage
Rao, J.; Xin, R.; Macdonald, C.; Howard, M.; Estevam, G. O.; Yee, S. W.; Wang, M.; Fraser, J. S.; Coyote-Maestas, W.; Pimentel, H.
10.1101/2023.10.24.562292 — bioinformatics — Posted on 2023-10-29
351 Enhancing Hi-C contact matrices for loop detection with Capricorn, a multi-view diffusion model
Fang, T.; Liu, Y.; Woicik, A.; Lu, M.; Jha, A.; Wang, X.; Li, G.; Hristov, B.; Liu, Z.; Xu, H.; Noble, W. S.; Wang, S.
10.1101/2023.10.25.564065 — bioinformatics — Posted on 2023-10-29
353 Addressing the dNTP bottleneck restricting prime editing activity
Ponnienselvan, K.; Liu, P.; Nyalile, T.; Oikemus, S.; Joynt, A. T.; Kelly, K.; Guo, D.; Chen, Z.; Lee, J. M.; Schiffer, C. A.; Emerson, C. P.; Lawson, N. D.; Watts, J. K.; Sontheimer, E. J.; Luban, J.; Wolfe, S. A.
10.1101/2023.10.21.563443 — biochemistry — Posted on 2023-10-29
355 A female heterogametic ZW sex-determination system in Acariformes
Wulsch, S.; Öztoprak, H.; Guiglielmoni, N.; Jeffries, D. L.; Bast, J.
10.1101/2023.10.24.563255 — genomics — Posted on 2023-10-29
356 Recombinant chimeric Horsepox Virus (TNX-801) is attenuated relative to Vaccinia Virus Strains in Human Primary Cell Lines and in Immunocompromised Mice
Trefry, S.; Raney, C.; Cregger, A.; Martinez, N.; Layton, B.; Enamorado, R.; Gohegan, D.; Moulaei, T.; Ziolkowska, N.; Goebel, S.; Lederman, S.; Bavari, S.; Nasar, F.
10.1101/2023.10.25.564033 — microbiology — Posted on 2023-10-29
359 Not seeing the forest for the trees: Combination of path integration and landmark cues in human virtual navigation
Scherer, J.; Muller, M. M.; Unterbrink, P.; Meier, S.; Egelhaaf, M.; Bertrand, O. J. N.; Boeddeker, N.
10.1101/2023.10.25.563902 — neuroscience — Posted on 2023-10-29
361 A novel Bayesian model for assessing intratumor heterogeneity of tumor infiltrating leukocytes with multi-region gene expression sequencing
Yang, P.; Hubert, S. M.; Futreal, P. A.; Song, X.; Zhang, J.; Lee, J. J.; Wistuba, I.; Yuan, Y.; Zhang, J.; Li, Z.
10.1101/2023.10.24.563820 — bioinformatics — Posted on 2023-10-29
367 The Marchantia pangenome reveals ancient mechanisms of plant adaptation to the environment
Beaulieu, C.; Libourel, C.; Mbadinga Zamar, D.-L.; El Mahboubi, K.; Hoey, D. J.; Keller, J.; Girou, C.; San Clemente, H.; Diop, I.; Amblard, E.; Theron, A.; Cauet, S.; Rodde, N.; Sabine, Z.; Halpape, W.; Meierhenrich, A.; Laker, B.; Braeutigam, A.; Greiff, G. R. L.; The SLCU Outreach Consortium, ; Szovenyi, P.; Cheng, S.; Tanizawa, Y.; Leebens-Mack, J. H.; Schmutz, J.; Webber, J.; Grimwood, J.; Jacquet, C.; Dunand, C.; Nelson, J.; Roux, F.; Philippe, H.; Schornack, S.; Bonhomme, M.; Delaux, P.-M.
10.1101/2023.10.27.564390 — plant biology — Posted on 2023-10-29
368 Quality control of Bradyrhizobium inoculant strains: Detection of nosZ and correlation of symbiotic efficiency with soybean leaf chlorophyll levels
Brignoli, D.; Frickel-Critto, E.; Sandobal, T. J.; Balda, R. S.; Castells, C. B.; Mongiardini, E. J.; Perez-Gimenez, J.; Lodeiro, A. R.
10.1101/2023.10.26.564198 — plant biology — Posted on 2023-10-29
371 A calibration protocol for soil-crop models aimed at reducing prediction error and inter-model variability
Wallach, D.; Buis, S.; Seserman, D.-M.; Palosuo, T.; Thorburn, P.; Mielenz, H.; Justes, E.; Kersebaum, K.-C.; Dumont, B.; Launay, M.; Seidel, S. J.
10.1101/2023.10.26.564162 — plant biology — Posted on 2023-10-29
372 Insecticidal Effects of Datura Species against Major Agricultural Pests
Sharma, M.; Singh, v. K.; Chaturvedi, D.; Delta, A. K.; Sharma, M. M.; Kaushik, P.
10.1101/2023.10.28.564503 — plant biology — Posted on 2023-10-29
373 Transport and inhibition mechanism for VMAT2-mediated synaptic loading of monoamines
Wang, Y.; Zhang, P.; Chao, Y.; Zhu, Z.; Yang, C.; Zhou, Z.; Li, Y.; Long, Y.; Liu, Y.; Li, D.; Wang, S.; Qu, Q.
10.1101/2023.10.27.564374 — biophysics — Posted on 2023-10-29
374 Docking for molecules that bind in a symmetric stack with SymDOCK
Smith, M. S.; Knight, I. S.; Kormos, R. C.; Pepe, J. G.; Kunach, P.; Diamond, M. I.; Shahmoradian, S. H.; Irwin, J. I.; DeGrado, W. F.; Shoichet, B. K.
10.1101/2023.10.27.564400 — biophysics — Posted on 2023-10-29
375 4D Crystallography Captures Transient IF1-Ribosome Dynamics in Translation Initiation
Yapici, I.; Dao, E. H.; Yokoi, S.; Destan, E.; Ayan, E.; Shafiei Kamel, A.; Ertem, F. B.; Kulakman, C.; Yilmaz, M.; Tosun, B.; Ciftci, H.; Kepceoglu, A.; Johnson, J. A.; Guven, O.; Ergul, A.; Hayes, B.; Rao, Y.; Kupitz, C. J.; Poitevin, F.; Liang, M.; Hunter, M. S.; Milon, P.; Mitsutake, A.; Sierra, R. G.; Wakatsuki, S.; DeMirci, H.
10.1101/2023.10.27.564398 — biophysics — Posted on 2023-10-29
377 Haematopoietic stem cell numbers are not solely determined by niche availability
Takeishi, S.; Marchand, T.; Koba, W. R.; Borger, D. K.; Xu, C.; Guha, C.; Bergman, A.; Frenette, P. S.; Gritsman, K.; Steidl, U.
10.1101/2023.10.28.564559 — cell biology — Posted on 2023-10-29
378 Fatty acid metabolism in neutrophils promotes lung damage and bacterial replication during tuberculosis.
Mishra, B. B.; Sankar, P.; Ramos, R. B.; Corro, J.; Saqib, M.; Nafiz, T. N.; Bhargavi, G.; Ojha, A. K.; Cai, Y.; Subbian, S.
10.1101/2023.10.25.563909 — immunology — Posted on 2023-10-29
380 Delineation of the pathogenic presynaptic mechanisms of synaptotagmin-1 variants
Melland, H.; Venter, K.; Leech, S. L.; Ferreira, A.; Arvell, E. H.; Baker, K.; Gordon, S. L.
10.1101/2023.10.29.564558 — neuroscience — Posted on 2023-10-29
381 The MuSK-BMP pathway regulates synaptic Nav1.4 localization and muscle excitability
Fish, L. A.; Ewing, M. D.; Jaime, D.; Rich, K. A.; Xi, C.; Wang, X. A.; Feder, R. E.; Wharton, K. A.; Rich, M. M.; Arnold, W. D.; Fallon, J. R.
10.1101/2023.10.24.563837 — neuroscience — Posted on 2023-10-29
382 Resolving spatiotemporal electrical signaling within the islet via CMOS microelectrode arrays
Gresch, A.; Huewel, J. D.; Briggs, J.; Berger, T.; Koch, R.; Deickert, T.; Beecks, C.; Benninger, R. K.; Duefer, M.
10.1101/2023.10.24.563843 — physiology — Posted on 2023-10-29
383 Involvement of TRPV4 in temperature-dependent perspiration in mice
Kashio, M.; Derouiche, S.; Yoshimoto, R. U.; Sano, K.; LEI, J.; Kido, M. A.; Tominaga, M.
10.1101/2023.10.25.563940 — physiology — Posted on 2023-10-29
385 FAK family proteins regulate in vivo breast cancer metastasis via distinct mechanisms.
Genna, A.; Alter, J.; Poletti, M.; Meirson, T.; Sneh, T.; Gendler, M.; Saleev, N.; Karagiannis, G.; Wang, Y.; Cox, D.; Entenberg, D.; Oktay, M.; Korcsmaros, T.; Condeelis, J.; Gil-Henn, H.
10.1101/2023.10.27.564212 — cancer biology — Posted on 2023-10-29
386 DREDge: robust motion correction for high-density extracellular recordings across species
Windolf, C.; Yu, H.; Paulk, A. C.; Meszena, D.; Munoz, W.; Boussard, J.; Hardstone, R.; Caprara, I.; Jamali, M.; Kfir, Y.; Xu, D.; Chung, J. E.; Sellers, K. K.; Ye, Z.; Shaker, J.; Lebedeva, A.; Raghavan, M.; Trautmann, E.; Melin, M. D.; Couto, J.; Garcia, S.; Coughlin, B.; Horvath, C.; Fiath, R.; Ulbert, I.; Movshon, J. A.; Shadlen, M. N.; Churchland, M. M.; Churchland, A. K.; Steinmetz, N. A.; Chang, E. F.; Schweitzer, J. S.; Williams, Z. M.; Cash, S. S.; Paninski, L.; Varol, E.
10.1101/2023.10.24.563768 — neuroscience — Posted on 2023-10-29
387 Cryptic diversity and signatures of domestication in the Black Soldier Fly (Hermetia illucens)
Generalovic, T. N.; Sandrock, C.; Roberts, B. J.; Meier, J. I.; Hauser, M.; Warren, I. A.; Pipan, M.; Durbin, R.; Jiggins, C. D.
10.1101/2023.10.21.563413 — genomics — Posted on 2023-10-29
389 Biosensor capability of the endometrium is mediated in part, by altered miRNA cargo from conceptus-derived extracellular vesicles.
De Bem, T. H. C.; Bridi, A.; Tinning, H.; Sampaio, R. V.; Malo-Estepa, I.; Wang, D.; Vasconcelos, E. J. R.; Nociti, R. P.; de Avila, A. C. F. C. M.; Sangalli, J. R.; Motta, I. G.; Arantes Ataide, G.; da Silva, J. C. B.; Fumie Watanabe, Y.; Gonella-Diaza, A.; da Silveira, J. C.; Pugliesi, G.; Vieira Meirelles, F.; Forde, N.
10.1101/2023.10.27.564369 — developmental biology — Posted on 2023-10-29
391 PAK1 and NF2/Merlin jointly drive myelination by remodeling actin cytoskeleton in oligodendrocytes
Baudouin, L.; Ades, N.; Kante, K.; Bachelin, C.; Hmidan, H.; Deboux, C.; Panic, R.; Ben Messaoud, R.; Hamada, S.; Pionneau, C.; Velut, Y.; Duarte, K.; Poën-Guyon, S.; Barnier, J.-V.; Nait Oumesmar, B.; Bouslama-Oueghlani, L.
10.1101/2023.10.16.555467 — neuroscience — Posted on 2023-10-29
394 Use of High Pressure NMR Spectroscopy to Rapidly Identify Proteins with Internal Ligand-Binding Voids
Gagne, D.; Azad, R.; Aramini, J. M.; Xu, X.; Isiorho, E. A.; Edupuganti, U. R.; Williams, J.; Marcelino, L. P.; Akasaka, K.; Gardner, K. H.
10.1101/2020.08.25.267195 — biophysics — Posted on 2023-10-29
395 Transcriptomic network analysis of brain and bone reveals shared molecular mechanisms underlyingAlzheimer's Disease and related dementias and Osteoporosis
Nagarajan, A.; Laird, J.; Ugochukwu, O.; Reppe, S.; Gautvik, K.; Ross, R. D.; Bennett, D. A.; Rosen, C. J.; Kiel, D. P.; Higginbotham, L. A.; Seyfried, N.; Lary, C. W.
10.1101/2023.10.26.559969 — neuroscience — Posted on 2023-10-28
396 Nature of epigenetic aging from a single-cell perspective
Tarkhov, A. E.; Lindstrom-Vautrin, T.; Zhang, S.; Ying, K.; Moqri, M.; Zhang, B.; Tyshkovskiy, A.; Levy, O.; Gladyshev, V. N.
10.1101/2022.09.26.509592 — systems biology — Posted on 2023-10-29
397 Precise Therapeutic Targeting of Distinct NRXN1+/- Mutations
Fernando, M. B.; Fan, Y.; Zhang, Y.; Kammourh, S.; Murphy, A. N.; Ghorbani, S.; Onatzevitch, R.; Pero, A.; Padilla, C.; Cao, L.; Williams, S.; Fang, G.; Slesinger, P. A.; Brennand, K.
10.1101/2023.10.28.564543 — neuroscience — Posted on 2023-10-28
405 Alternative splicing controls teneurin-3 compact dimer formation for neuronalrecognition
Gogou, C.; Beugelink, J. W.; Pereira Frias, C. S.; Kresik, L. K.; Jaroszynska, N.; Drescher, U.; Janssen, B. J. C.; Hindges, R.; Meijer, D. H.
10.1101/2023.10.27.564434 — biochemistry — Posted on 2023-10-28
406 The core microbiome of cultured Pacific oyster spat develops with age but not mortality
Cho, A.; Finke, J. F.; Zhong, K. X.; Chan, A. M.; Saunders, R.; Schulze, A.; Warne, S.; Miller, K. M.; Suttle, C. A.
10.1101/2023.10.27.564467 — microbiology — Posted on 2023-10-28
407 Diversity of RNA viruses in declining Mediterranean forests
Diez-Hermano, S.; Perez-Alonso, P. L.; Acosta-Morel, W.; Nino-Sanchez, J.; de la Pena, M.; Diez, J. J.
10.1101/2023.10.28.564537 — microbiology — Posted on 2023-10-28
409 Gut microbiota promotes pain in fibromyalgia
Cai, W.; Haddad, M.; Haddad, R.; Kesten, I.; Hoffman, T.; Laan, R.; Wong, W.; Brown, N.; Tansley, S.; Lister, K. C.; Hooshmandi, M.; Wang, F.; Sharif, B.; Westfall, S.; Sahar, T.; Clayton, C.; Wu, N.; Zhang, J.; Bar-Yoseph, H.; Pitashny, M.; Mogil, J. S.; Prager-Khoutorsky, M.; Seguela, P.; King, I. L.; De Koninck, Y.; Brereton, N. J. B.; Gonzalez, E.; Shir, Y.; Minerbi, A.; Khoutorsky, A.
10.1101/2023.10.24.563794 — neuroscience — Posted on 2023-10-28
410 APOE4 poses opposite effects of plasma LDL on white matter integrity in older adults
Ye, Z.; Pan, Y.; McCoy, R. G.; Chuan, B.; Chen, M.; Feng, L.; Yu, J.; Lu, T.; Liu, S.; Gao, S.; Hatch, K. S.; Ma, Y.; Chen, C.; Mitchell, B. D.; Thompson, P. M.; Hong, L. E.; Kochunov, P.; MA, T.; Chen, S.
10.1101/2023.10.24.563796 — neuroscience — Posted on 2023-10-28
411 Complement C1q-dependent engulfment of alpha-synuclein induces ENS-resident macrophage exhaustion and accelerates Parkinsons-like gut pathology
Mackie, P. M.; Koshy, J.; Bhogade, M.; Hammoor, T.; Hachmeister, W.; Lloyd, G. M.; Paterno, G.; Bolen, M.; Tansey, M. G.; Giasson, B.; Khoshbouei, H.
10.1101/2023.10.24.563832 — neuroscience — Posted on 2023-10-28
412 Forest tree extracts induce resistance to Pseudomonas syringae pv. tomato in Arabidopsis
Soltaniband, V.; Barrada, A.; Delisle-Houde, M.; Dorais, M.; Tweddell, R. J.; Michaud, D.
10.1101/2023.10.24.563420 — plant biology — Posted on 2023-10-28
413 Determining the defining lengths between mature microRNAs/small interfering RNAs and tinyRNAs
Sim, G.; Kehling, A. C.; Park, M. S.; Divoky, C.; Zhang, H.; Malhotra, N.; Secor, J.; Nakanishi, K.
10.1101/2023.10.27.564437 — biochemistry — Posted on 2023-10-28
414 Streamlined DNA template preparation and co-transcriptional 5' capped RNA synthesis enabled by solid-phase catalysis
Marquina, G. G.; Zhang, A.; Sproviero, M.; Fang, Y.; Gardner, A. F.; Robb, G. B.; Chan, S. H.; Xu, M.-Q.
10.1101/2023.10.28.564520 — biochemistry — Posted on 2023-10-28
415 Reconstitution of cytolinker-mediated crosstalk between actin and vimentin
Isturiz Petitjean, I.; Tran, Q. D.; Goutou, A.; Kabir, Z.; Wiche, G.; Leduc, C.; Koenderink, G. H.
10.1101/2023.10.27.564417 — biochemistry — Posted on 2023-10-28
418 Spatially resolved distribution of pancreatic hormones proteoforms by MALDI-imaging mass spectrometry
Sisnande, T.; Brum, F. L.; Matias, D. O.; Ribeiro, F. S.; Moulin, T. B.; Mohana-Borges, R. S.; Magalhaes, M. T.; Lima, L. M. T.
10.1101/2023.10.27.564470 — biochemistry — Posted on 2023-10-28
420 High-quality genome assemblies of four members of the Podospora anserina species complex
Ament-Velasquez, S. L.; Vogan, A. A.; Wallerman, O.; Hartmann, F. E.; Gautier, V.; Silar, P.; Giraud, T.; Johannesson, H.
10.1101/2023.10.24.563784 — genomics — Posted on 2023-10-28
424 HDAC activity is dispensable for repression of cell-cycle genes by DREAM and E2F:RB complexes
Barrett, A. K.; Shingare, M. R.; Rechtsteiner, A.; Wijeratne, T. U.; Rodriguez, K. M.; Rubin, S. M.; Müller, G. A.
10.1101/2023.10.28.564489 — molecular biology — Posted on 2023-10-28
425 Cell surface architecture of the cultivated DPANN archaeon Nanobdella aerobiophila
Kato, S.; Tahara, Y. O.; Nishimura, Y.; Uematsu, K.; Arai, T.; Nakane, D.; Ihara, A.; Nishizaka, T.; Iwasaki, W.; Itoh, T.; Miyata, M.; Ohkuma, M.
10.1101/2023.10.27.564410 — microbiology — Posted on 2023-10-28
427 Inhibition of Pseudomonas aeruginosa quorum sensing by chemical induction of the MexEF-oprN efflux pump
Kristensen, R.; Andersen, J. B.; Levin Rybtke, M.; Jansen, C. U.; Fritz, B. G.; Kiilerich, R.; Uhd, J.; Bjarnsholt, T.; Qvortrup, K.; Tolker-Nielsen, T.; Givskov, M.; Jakobsen, T. H.
10.1101/2023.10.27.564458 — microbiology — Posted on 2023-10-28
429 Deciphering the biology and chemistry of the mutualistic partnership between Bacillus velezensis and the arbuscular mycorrhizal fungus Rhizophagus irregularis
Anckaert, A.; Declerck, S.; Poussart, L.-A.; Lambert, S.; Helmus, C.; Boubsi, F.; Steels, S.; Arguelles Arias, A.; Calonne-Salmon, M.; ongena, m.
10.1101/2023.10.28.564539 — microbiology — Posted on 2023-10-28
430 A novel bioinformatics pipeline for the identification of immune inhibitory receptors as potential therapeutic targets
Singh, A.; Miranda Bedate, A.; von richthofen, H. J.; van der Vlist, M.; Kuhn, R.; Yermanos, A.; Kuball, J. J.; Kesmir, C.; Pascoal Ramos, M. I.; Meyaard, L.
10.1101/2023.10.24.563834 — immunology — Posted on 2023-10-28
433 LOXL2 inhibition ameliorates pulmonary artery remodeling in pulmonary hypertension
Steppan, J.; Wang, H.; Nandakumar, K.; Poe, A.; Pak, L.; Brady, T.; Gadkari, M.; Berkowitz, D. E.; Shimoda, L. A.; Santhanam, L.
10.1101/2023.10.24.563874 — physiology — Posted on 2023-10-28
435 Not all Bacterial Outer-membrane Proteins are β-Barrels
Heido, J.; Keng, S.; Poyrazoglu, H.; Priyam, E.; Jayasinghe, S.
10.1101/2023.10.25.564060 — bioinformatics — Posted on 2023-10-28
436 Targeted genome editing restores auditory function in adult mice with progressive hearing loss caused by a human microRNA mutation
Zhu, W.; Du, W.; Rameshbabu, A. P.; Armstrong, A. M.; Silver, S.; Kim, Y.; Wei, W.; Shu, Y.; Liu, X.; Lewis, M. A.; Steel, K. P.; Chen, Z.-Y.
10.1101/2023.10.26.564008 — bioengineering — Posted on 2023-10-28
437 Microbubble dynamics in brain microvessels
Bezer, J. H.; Prentice, P.; Lim Kee Chang, W.; Morse, S. V.; Christensen-Jeffries, K.; Rowlands, C. J.; Kozlov, A.; Choi, J. J.
10.1101/2023.10.25.563941 — bioengineering — Posted on 2023-10-28
439 Metabolic similarity and the predictability of microbial community assembly
Vila, J. C. C.; Goldford, J.; Estrela, S.; Bajic, D.; Sanchez-Gorostiaga, A.; Damian-Serrano, A.; Lu, N.; Marsland, R.; Rebolleda-Gomez, M.; Mehta, P.; Sanchez, A.
10.1101/2023.10.25.564019 — ecology — Posted on 2023-10-28
441 DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity
Luo, W.; Che, H.; Fan, L.; Guo, Q.; Wong, M. Y.; Yu, F.; Foxe, N.; Wang, W.; Nessim, A.; Carling, G.; Liu, B.; Lopez-Lee, C.; Huang, Y.; Amin, S.; Patel, T.; Mok, S.-A.; Song, W.-m.; Zhang, B.; Ma, Q.; Fu, H.; Gan, L.
10.1101/2023.10.26.563970 — neuroscience — Posted on 2023-10-28
447 Integrated integral population models
Portillo-Tzompa, P.; Martin-Cornejo, P. R.; Gonzalez, E. J.
10.1101/2023.10.24.563870 — ecology — Posted on 2023-10-28
450 Early human fetal lung atlas reveals the temporal dynamics of epithelial cell plasticity.
Quach, H. T.; Farrell, S.; Kanagarajah, K.; Wu, M.; Xu, X.; Kallurkar, P.; Turinsky, A.; Bear, C.; Ratjen, F.; Goyal, S.; Moraes, T. J.; Wong, A.
10.1101/2023.10.27.564403 — developmental biology — Posted on 2023-10-28
451 SOX2+ sustentacular cells are stem cells of the postnatal adrenal medulla
Santambrogio, A.; Kemkem, Y.; Willis, T. L.; Berger, I.; Kastriti, M. E.; Faure, L.; Russell, J. P.; Lodge, E. J.; Yianni, V.; Oakey, R. J.; Altieri, B.; Bornstein, S. R.; Steenblock, C.; Adameyko, I. I.; Andoniadou, C. L.
10.1101/2023.10.28.564519 — developmental biology — Posted on 2023-10-28
453 A journey to understanding larval quality in fish by integrating transcriptomics and zootechnics
Debernardis, R.; Palinska-Zarska, K.; Judycka, S.; Panda, A.; Jarmolowicz, S.; Jastrzebski, J. P.; de Almeida, T.; Blazejewski, M.; Hliwa, P.; Krejszeff, S.; Zarski, D.
10.1101/2023.10.27.564361 — developmental biology — Posted on 2023-10-28
455 An interplay of HSP-proteostasis, biomechanics and ECM-cell junctions ensures C. elegans astroglial architecture
Coraggio, F.; Bhushan, M.; Roumeliotis, S.; Caroti, F.; Bevilacqua, C.; Prevedel, R.; Rapti, G.
10.1101/2023.10.28.564505 — cell biology — Posted on 2023-10-28
458 Altered PBP4 and GdpP functions synergistically mediate MRSA-like high-level, broad-spectrum β-lactam resistance in Staphylococcus aureus
Lai, L.-Y.; Satishkumar, N.; Cardozo, S.; Hemmadi, V.; Marques, L. B.; Huang, L.; Filipe, S. R.; Pinho, M. G.; Chambers, H. F.; Chatterjee, S. S.
10.1101/2023.10.26.564222 — microbiology — Posted on 2023-10-28
459 A spatial human thymus cell atlas mapped to a continuous tissue axis
Yayon, N.; Kedlian, V. R.; Boehme, L.; Suo, C.; Wachter, B.; Beuschel, R. T.; Amsalem, O.; Polanski, K.; Koplev, S.; Tuck, E.; Dann, E.; Van Hulle, J.; Perera, S.; Putteman, T.; Predeus, A. V.; Dabrowska, M.; Richardson, L.; Tudor, C.; Kreins, A. Y.; Engelbert, J.; Stephenson, E.; Kleshchevnikov, V.; De Rita, F.; Crossland, D.; Bosticardo, M.; Pala, F.; Prigmore, E.; Chipampe, N.-J.; Prete, M.; Fei, L.; To, K.; Barker, R. A.; He, X.; Van Nieuwerburgh, F.; Bayraktar, O.; Patel, M.; Davies, G. E.; Haniffa, M. A.; Uhlmann, V.; Notarangelo, L. D.; Germain, R. N.; Radtke, A. J.; Marioni, J. C.; Tag
10.1101/2023.10.25.562925 — immunology — Posted on 2023-10-28
460 Natural variation in oxytocin receptor signaling causes widespread changes in brain transcription: a link to the natural killer gene complex
Boender, A. J.; Johnson, Z. V.; Gruenhagen, G. W.; Horie, K.; Hegarty, B. E.; Streelman, J. T.; Walum, H.; Young, L. J.
10.1101/2023.10.26.564214 — neuroscience — Posted on 2023-10-28
462 Hyperbolic graph embedding of MEG brain networks to study brain alterations in individuals with subjective cognitive decline
Baker, C.; Mendez, I. S.; Smith, G.; Marsh, E. B.; Funke, M.; Mosher, J. C.; Maestu, F.; Xu, M.; Pantazis, D.
10.1101/2023.10.23.563643 — bioinformatics — Posted on 2023-10-28
463 Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling
Zoltowska, K. M.; Das, U.; Lismont, S.; Enzlein, T.; Maesako, M.; Houser, M. C.; Gomes Moreira, D.; Franco, M. L.; Karachentsev, D.; Becker, A.; Hopf, C.; Vilar, M.; Berezovska, O.; Mobley, W.; Chavez-Gutierrez, L.
10.1101/2023.08.02.551596 — biochemistry — Posted on 2023-10-28
464 Expanding the Drosophila toolkit for dual control of gene expression
Zirin, J.; Jusiak, B.; Lopes, R.; Ewen-Campen, B.; Bosch, J.; Risbeck, A.; Forman, C.; Villalta, C.; Hu, Y.; Perrimon, N.
10.1101/2023.08.15.553399 — genetics — Posted on 2023-10-28
465 The molecular architecture of the kidney slit diaphragm
Birtasu, A. N.; Wieland, K.; Ermel, U. H.; Rahm, J. V.; Scheffer, M. P.; Flottmann, B.; Heilemann, M.; Grahammer, F.; Frangakis, A. S.
10.1101/2023.10.27.564405 — cell biology — Posted on 2023-10-28
466 The olivary input to the cerebellum dissociates sensory events from movement plans
Pi, J. S.; Fakharian, M. A.; Hage, P.; Sedaghat-Nejad, E.; Muller, S. Z.; Shadmehr, R.
10.1101/2022.07.11.499614 — neuroscience — Posted on 2023-10-28
473 High-resolution CTCF footprinting reveals impact of chromatin state on cohesin extrusion dynamics
Sept, C. E.; Tak, Y. E.; Cerda-Smith, C. G.; Hutchinson, H. M.; Goel, V.; Blanchette, M.; Bhakta, M. S.; Hansen, A. S.; Joung, J. K.; Johnstone, S.; Eyler, C. E.; Aryee, M. J.
10.1101/2023.10.20.563340 — genomics — Posted on 2023-10-28
475 Exploratory Correlation of the Human Structural Connectome with Non-MRI Variables in Alzheimer's Disease
Aganj, I.; Mora, J.; Frau-Pascual, A.; Fischl, B. R.; Alzheimer's Disease Neuroimaging Initiative,
10.1101/2023.06.30.547308 — neuroscience — Posted on 2023-10-28
478 Information Geometry of the Retinal Representation Manifold
Ding, X.; Lee, D.; Melander, J. B.; Sivulka, G.; Ganguli, S.; Baccus, S. A.
10.1101/2023.05.17.541206 — neuroscience — Posted on 2023-10-28
481 On the pH-dependence of α-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation
Frey, L.; Ghosh, D.; Qureshi, B. M.; Rhyner, D.; Guerrero-Ferreira, R.; Pokharna, A.; Kwiatkowski, W.; Serdiuk, T.; Picotti, P.; Riek, R.; Greenwald, J.
10.1101/2023.06.25.546428 — biophysics — Posted on 2023-10-28
484 Protein Dynamics Govern the Oxyferrous State Lifetime of an Artificial Oxygen Transport Protein
Zhang, L.; Brown, M. C.; Mutter, A. C.; Greenland, K. N.; Cooley, J. W.; Koder, R. L.
10.1101/2023.06.09.544418 — biophysics — Posted on 2023-10-28
487 Concerted regulation of skeletal muscle metabolism and contractile properties by the orphan nuclear receptor Nr2f6
Guimaraes, D. S. P. S. F.; Barrios, N. M. F.; de Oliveira, A. G.; Rizo-Roca, D.; Jollet, M.; Smith, J. A. B.; Araujo, T. R.; da Cruz, M. V.; Vieira, A. S.; Hirabara, S. M.; Marconato, E.; Krook, A.; Zierath, J. R.; Silveira, L. d. R.
10.1101/2023.05.17.540900 — biochemistry — Posted on 2023-10-28
488 Activation-induced shift in nutrient preference and function-specific nutrient dependence in human neutrophils
Britt, E. C.; Qing, X.; Votava, J. A.; Lika, J.; Wagner, A.; Shen, S.; Arp, N. L.; Khan, H.; Schieke, S. M.; Fletcher, C. D.; Huttenlocher, A.; Fan, J.
10.1101/2023.09.25.559385 — biochemistry — Posted on 2023-10-28
491 Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function
Chang, C.; Banerjee, S. L.; Park, S. S.; Zhang, X.; Cotnoir-White, D.; Opperman, K. J.; Desbois, M.; Grill, B.; Kania, A.
10.1101/2023.06.12.544638 — cell biology — Posted on 2023-10-28
492 The lipid flippase ATP10B enables cellular lipid uptake under stress conditions
Wouters, R.; Beletchi, I.; Van den Haute, C.; Baekelandt, V.; Martin, S.; Eggermont, J.; Vangheluwe, P.
10.1101/2023.06.01.543059 — cell biology — Posted on 2023-10-28
494 The ASC inflammasome adapter controls the extent of peripheral protein aggregate deposition in inflammation-associated amyloidosis
Losa, M.; Emmenegger, M.; De Rossi, P.; Schuerch, P. M.; Serdiuk, T.; Pengo, N.; Capron, D.; Bieli, D.; Rupp, N. J.; Carta, M. C.; Frontzek, K. J.; Lysenko, V.; Reimann, R.; Lakkaraju, A. K.; Nuvolone, M.; Westermark, G. T.; Nilsson, K. P.; Polymenidou, M.; Theocharides, A. P.; Hornemann, S.; Picotti, P.; Aguzzi, A.
10.1101/2021.05.01.442282 — molecular biology — Posted on 2023-10-28
495 Synaptopodin regulates denervation-induced plasticity at hippocampal mossy fiber synapses
Kruse, P.; Brandes, G.; Hemeling, H.; Huang, Z.; Wrede, C.; Hegermann, J.; Vlachos, A.; Lenz, M.
10.1101/2022.10.23.513396 — neuroscience — Posted on 2023-10-28
496 Circuit structural plasticity by a neurotrophin with a Toll modifies behaviour
SUN, J.; ULIAN-BENITEZ, S.; FORERO, M. G.; LI, G.; SINGH, D.; ROJO-CORTES, F. R.; WANG, X.; CACHERO, S.; MOREIRA, M.; KAVANAGH, D.; JEFFERIS, G. S. X. E.; CROSET, V.; HIDALGO, A.
10.1101/2023.01.04.522695 — neuroscience — Posted on 2023-10-28
497 Structural characterization of SLYM - a 4th meningeal membrane
Pl, V.; Bitsika, S.; Giannetto, M.; Ladron-de-Guevara, A.; Gahn Martinez, D.; Mori, Y.; Nedergaard, M.; Mollgard, K.
10.1101/2023.10.20.563351 — neuroscience — Posted on 2023-10-28
498 Neural circuits for fast Poisson compressed sensing in the olfactory bulb
Zavatone-Veth, J. A.; Masset, P.; Tong, W. L.; Zak, J. D.; Murthy, V. N.; Pehlevan, C.
10.1101/2023.06.21.545947 — neuroscience — Posted on 2023-10-28
502 ATR promotes mTORC1 activation via de novo cholesterol synthesis in p16-low cancer cells
Tangudu, N. K.; Huang, Z.; Fang, R.; Buj, R.; Uboveja, A.; Cole, A. R.; Happe, C.; Sun, M.; Gelhaus, S. L.; Hempel, N.; Snyder, N. W.; Aird, K. M.
10.1101/2023.10.27.564195 — cancer biology — Posted on 2023-10-28
504 Spatial N-glycan rearrangement on α5β1 integrin nucleates galectin-3 oligomers to determine endocytic fate α
Shafaq-Zadah, M.; Dransart, E.; Wunder, C.; Chambon, V.; Valades-Cruz, C. A.; Leconte, L.; Kumar Sarangi, N.; Robinson, J.; Bai, S.-K.; Regmi, R.; Di Cicco, A.; Hovasse, A.; Bartels, R.; Nilsson, U.; Cianferani-Sanglier, S.; Leffler, H.; Keyes, T.; Levy, D.; Raunser, S.; Roderer, D.; Johannes, L.
10.1101/2023.10.27.564026 — cell biology — Posted on 2023-10-27
505 The molecular architecture of the kidney slit diaphragm
Frangakis, A. S.; Grahammer, F.; Heilemann, M.; Flottmann, B.; Scheffer, M. P.; Rahm, J. V.; Wieland, K.; Birtasu, A. N.
10.1101/2023.10.27.564405 — cell biology — Posted on 2023-10-27
508 Atypical Protein Kinase C Promotes its own Asymmetric Localisation by Phosphorylating Cdc42 in Polarising Cells
Packer, J.; Gubieda, A. G.; Brooks, A.; Deutz, L. N.; Squires, I.; Ellison, S.; Naganathan, S. R.; Wollman, A. J. M.; Dickinson, D. J.; Rodriguez, J.
10.1101/2023.10.27.563985 — cell biology — Posted on 2023-10-28
509 Plexin-B1 and Plexin-B2 play non-redundant roles in GABAergic synapse formation
Adel, S.; Pranske, Z. J.; Kowalski, T. F.; Kanzler, N.; Ray, R.; Carmona, C.; Paradis, S.
10.1101/2023.10.27.564428 — neuroscience — Posted on 2023-10-27
511 Transcriptomic Landscape of Hyperthyroidism in Mice Overexpressing Thyroid Stimulating Hormone
Yamauchi, I.; Sugawa, T.; Hakata, T.; Yoshizawa, A.; Kita, T.; Kishimoto, Y.; Kimura, S.; Kosugi, D.; Fujita, H.; Okamoto, K.; Ueda, Y.; Fujii, T.; Taura, D.; Sakane, Y.; Yasoda, A.; Inagaki, N.
10.1101/2023.10.27.564354 — physiology — Posted on 2023-10-27
513 Trait selection strategy in multi-trait GWAS: Boosting SNPs discoverability
Suzuki, Y.; Menager, H.; Brancotte, B.; Vernet, R.; Nerin, C.; Boetto, C.; Auvergne, A.; Linhard, C.; Torchet, R.; Lechat, P.; Troubat, L.; Cho, M. H.; Bouzigon, E.; Aschard, H.; Julienne, H.
10.1101/2023.10.27.564319 — genetics — Posted on 2023-10-27
516 Aberrant Local Synchrony in Distinct Mouse Models of Epileptic Encephalopathy
Ressler, A.; Dugger, S.; Colombo, S.; Petri, S.; Krizay, D.; Frankel, W.; Goldstein, D.; Boland, M. J.
10.1101/2023.10.24.563817 — neuroscience — Posted on 2023-10-27
518 A Fuzzy sequencer for rapid DNA fragment counting and genotyping
Zhou, W.; Kang, L.; Qiao, S.; Duan, H.; Yin, C.; Liao, Z.; Tang, M.; Zhang, R.; Li, L.; Shi, L.; Du, M.; Wang, Y.; Yue, W.; Xiao, Y.; Di, L.; Zhang, X.; Pang, Y.; Li, M.; Ren, L.; Wang, J.; Chen, Z.; Huang, Y.
10.1101/2023.10.24.563729 — genomics — Posted on 2023-10-27
519 Modular vector assembly enables rapid assessment of emerging CRISPR technologies
McGee, A. V.; Liu, Y. V.; Griffith, A. L.; Szegletes, Z. M.; Wen, B.; Kraus, C.; Miller, N. W.; Steger, R. J.; Escude Velasco, B.; Bosch, J. A.; Zirin, J. D.; Viswanatha, R.; Sontheimer, E. J.; Goodale, A.; Greene, M. A.; Green, T. M.; Doench, J. G.
10.1101/2023.10.25.564061 — genomics — Posted on 2023-10-27
520 Bioelectrical Synchronisation of Spruce Trees during aSolar Eclipse
Chiolerio, A.; Gagliano, M.; Pilia, S.; Pilia, P.; Vitiello, G.; Dehshibi, M. M.; Adamatzky, A.
10.1101/2023.10.24.563666 — plant biology — Posted on 2023-10-27
521 Structural adaptability and surface activity oftardigrade-inspired peptides
Giubertoni, G.; Chagri, S.; Argudo, P. G.; Caporaletti, F.; Greco, A.; Pradel, L.; Pavan, A.; Ilie, I. M.; Ren, Y.; Ng, D.; Bonn, M.; Weil, T.; Woutersen, S.
10.1101/2023.10.27.564388 — biochemistry — Posted on 2023-10-27
523 HLTF Prevents G4 Accumulation and Promotes G4-induced Fork Slowing to Maintain Genome Stability
Bai, G.; Endres, T.; Kühbacher, U.; Greer, B. H.; Peacock, E. M.; Crossley, M. P.; Sathirachinda, A.; Cortez, D.; Eichman, B. F.; Cimprich, K. A.
10.1101/2023.10.27.563641 — molecular biology — Posted on 2023-10-27
528 Engineered Reversible Inhibition of SpyCatcher Reactivity Enables Rapid Generation of Bispecific Antibodies
Hentrich, C.; Putyrski, M.; Hanuschka, H.; Preis, W.; Kellmann, S.-J.; Wich, M.; Cavada, M.; Hanselka, S.; Ylera, F.
10.1101/2023.10.27.564397 — biochemistry — Posted on 2023-10-27
531 Drosophila models of PIGA-CDG mirror patient phenotypes
Thorpe, H. J.; Owings, K. G.; Aziz, M. C.; Haller, M.; Coelho, E.; Chow, C. Y.
10.1101/2023.10.27.564441 — genetics — Posted on 2023-10-27
532 Genome rearrangements drive evolution of ANK genes in Wolbachia
Vostokova, E. V.; Dranenko, N. O.; Gelfand, M. S.; Bochkareva, O. O.
10.1101/2023.10.25.563763 — evolutionary biology — Posted on 2023-10-27
533 Pervasive relaxed selection on spermatogenesis genes coincident with the evolution of polygyny in gorillas
Bowman, J. D.; Silva, N.; Schüueftan, E.; Almeida, J. M.; Brattig-Correia, R.; Oliveira, R. A.; Tüttelmann, F. J.; Enard, D.; Navarro-Costa, P.; Lynch, V. J.
10.1101/2023.10.27.564379 — evolutionary biology — Posted on 2023-10-27
534 Adipokinetic hormone signaling mediates the fecundity of Diaphorina citri infected by Candidatus Liberibacter asiaticus
Li, J.; Holford, P.; Beattie, G. A. C.; Wu, S.; He, J.; Tan, S.; Wang, D.; He, Y.; Cen, Y.; Nian, X.
10.1101/2023.10.24.563719 — ecology — Posted on 2023-10-27
535 SCD1 and monounsaturated lipids are required for autophagy and survival of adipocytes
Mori, H.; Peterson, S. K.; Simmermon, R.; Overmyer, K.; Nishii, A.; Paulsson, E.; Ziru, L.; Jen, A.; Uranga, R. M.; Maung, J.; Yacawych, W. T.; Lewis, K. T.; Schill, R. L.; Hetrick, T.; Seino, R.; Inoki, K.; Coon, J.; MacDougald, O. A.
10.1101/2023.10.27.564376 — molecular biology — Posted on 2023-10-27
539 A high-content RNA-based imaging assay reveals integrin beta 1 as a cofactor for cell entry of non-enveloped hepatitis E virus
Fu, R. M.; Engels, Z.; Wheis, J. A.; Muerle, J.; Kloehn, M.; Todt, D.; Hu, J.; Steinmann, E.; Boettler, T.; Lozach, P.-Y.; Lemon, S. M.; Dao Thi, V. L.
10.1101/2023.10.27.564362 — microbiology — Posted on 2023-10-27
543 Molecular control of the lymphocyte death timer
Ruhle, M.; Thomas, E.; Dann, E.; Gottscheber, N.; Teh, C. E.; Gray, D. H.; Dowling, M. R.; Heinzel, S.; Hodgkin, P. D.
10.1101/2023.10.25.563681 — immunology — Posted on 2023-10-27
544 Reassessment of the risks of climate change for terrestrial ecosystems
Conradi, T.; Eggli, U.; Kreft, H.; Schweiger, A. H.; Weigelt, P.; Higgins, S. I.
10.1101/2023.10.24.563567 — ecology — Posted on 2023-10-27
545 Integrated spatial protein and RNA analysis on the same section using MICS technology
Neil, E.; Park, D.; Hennessey, R. C.; DiBiasio, E. C.; DiBuono, M.; Lafayette, H.; Lloyd, E.; Lo, H.; Femel, J.; Makrigiorgos, A.; Soliman, S.; Mangiardi, D.; Praveen, P.; Rüberg, S.; Staubach, F.; Hindman, R.; Rothmann, T.; Meyer, H.; Wantenaar, T.; Wang, J.; Müller, W.; Pinard, R.; Bosio, A.
10.1101/2023.10.27.564191 — molecular biology — Posted on 2023-10-27
547 Fine-Tuning and Remodelling of Pectins Play a Key Role in the Maintenance of Cell Adhesion
Grandjean, C.; Voxeur, A.; Chabout, S.; Francois, J.; Gutierrez, L.; Pelloux, J.; Mouille, G.; Bouton, S.
10.1101/2023.10.27.564335 — plant biology — Posted on 2023-10-27
550 Individual tree crown maps for the National Ecological Observatory Network
Weinstein, B.; Marconi, S.; Zare, A.; Bohlman, S.; Singh, A.; Graves, S. J.; Magee, L.; Johnson, D. J.; Record, S.; Rubio, V. E.; Swenson, N. G.; Veblen, T.; Townsend, P.; Andrus, R. A.; White, E. P.
10.1101/2023.10.25.563626 — ecology — Posted on 2023-10-27
551 Movement-related drivers of exposure to West Nile virus by American robins (Turdus migratorius)
Jahn, A. E.; Koller, K. K.; Martin, L. B.; Smiley, T. M.; Verrett, T. B.; Ketterson, E. D.; Williams, E. J.; Becker, D.
10.1101/2023.10.27.562968 — ecology — Posted on 2023-10-27
552 Drab and distant birds are studied less than their fancy-feathered friends
Fischer, S. E.; Lindsay, A. M.; Otten, J. G.; Miles, D. B.; Streby, H. M.
10.1101/2023.10.26.560707 — ecology — Posted on 2023-10-27
554 Overcoming antibody-resistant SARS-CoV-2 variants with bispecific antibodies constructed using non-neutralizing antibodies
Inoue, T.; Yamamoto, Y.; Sato, K.; Nakamura, Y.; Shimizu, Y.; Ogawa, M.; Onodera, T.; Takahashi, Y.; Wakita, T.; Kaneko, M. K.; Fukasawa, M.; Kato, Y.; Noguchi, K.
10.1101/2023.10.26.564289 — microbiology — Posted on 2023-10-27
555 Viral genomic features predict orthopoxvirus reservoir hosts
Tseng, K. K.; Koehler, H.; Becker, D. J.; Gibb, R.; Carlson, C. J.; Fernandez, M. d. P.; Seifert, S. N.
10.1101/2023.10.26.564211 — microbiology — Posted on 2023-10-27
556 Immune Epitopes of SARS-CoV-2 Spike Protein and Considerations for Universal Vaccine Development
Magazine, N.; Zhang, T.; Bungwon, A. D.; McGee, M. C.; Wu, Y.; Veggiani, G.; Huang, W.
10.1101/2023.10.26.564184 — immunology — Posted on 2023-10-27
557 Impact of Memory T Cells on SARS-COV-2 Vaccine Response in Hematopoietic Stem Cell Transplant
VanOudenhove, J. J.; Liu, Y.; Nelakanti, R.; Kim, D.; Busarello, E.; Tijaro Ovalle, N.; Qi, Z.; Mamillapalli, P.; Siddon, A.; Bai, Z.; Axtmayer, A.; Corso, C.; Kothari, S.; Foss, F.; Isufi, I.; Tebaldi, T.; Gowda, L.; Fan, R.; Seropian, S.; Halene, S.
10.1101/2023.10.26.564259 — immunology — Posted on 2023-10-27
558 Pharmacological enhancement of dopamine neurotransmission does not affect illusory pattern perception
Smith, E.; Michalski, S.; Knauth, K.; Tuzsus, D.; Theis, H.; van Eimeren, T.; Peters, J.
10.1101/2023.10.24.563723 — neuroscience — Posted on 2023-10-27
559 WOX11-mediated cell size control in Arabidopsis attenuates fecundity of endoparasitic cyst nematodes
Guarneri, N.; Willig, J.-J.; Willemsen, V.; Goverse, A.; Sterken, M. G.; Nibbering, P.; Lozano-Torres, J. L.; Smant, G.
10.1101/2023.10.27.564344 — plant biology — Posted on 2023-10-27
560 Lethal COVID-19 Associates With RAAS-Induced Inflammation For Multiple Organ Damage Including Mediastinal Lymph Nodes
Guarnieri, J. W.; Topper, M.; Beigel, K.; Haltoom, J. A.; Chadburn, A.; Frere, J.; An, J.; Cope, H.; Borczuk, A.; Sinha, S.; Lim, C.; Kim, J.; Park, J.; Meydan, C.; Foox, J.; Mozsary, C.; Bram, Y.; Richard, S.; Epsi, N.; Agan, B.; Chenoweth, J.; Simons, M.; Tribble, D.; Burgess, T.; Dalgard, C. L.; Heise, M. T.; Moorman, N.; Baxter, V.; Madden, E. A.; Taft-Benz, S.; Anderson, E.; Sanders, W. A.; Dickmander, R. J.; Widjaja, G. A.; Janssen, K.; Lie, T.; Murdock, D. G.; Angelin, A.; Albrecht, Y. E. S.; Olali, A.; Cen, Z.; Dybas, J. M.; Priebe, W.; Emmett, M. R.; Best, S.; Johnson, M. K.; Clark, K
10.1101/2023.10.08.561395 — immunology — Posted on 2023-10-27
561 RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with STMN-2 cryptic splicing and precedes clinical manifestation in ALS
Spence, H.; Waldron, F. M.; Saleeb, R. S.; Brown, A.-L.; Rifai, O. M.; Gilodi, M.; Read, F.; Roberts, K.; Milne, G.; Wilkinson, D.; O'Shaughnessy, J.; Pastore, A.; Fratta, P.; Shneider, N.; Tartaglia, G. G.; Zacco, E.; Horrocks, M. H.; Gregory, J.
10.1101/2023.10.24.563701 — neuroscience — Posted on 2023-10-27
562 Degradation of Fatty Acid Export Protein1 by Rhomboid-Like Protease11 Contributes to Cold Tolerance in Arabidopsis
John, A.; Kraemer, M.; Lehmann, M.; Kunz, H.-H.; Aarabi, F.; Alseekh, S.; Fernie, A. R.; Sommer, F.; Schroda, M.; Zimmer, D.; Muehlhaus, T.; Peisker, H.; Gutbrod, K.; Doermann, P.; Neunzig, J.; Philippar, K.; Neuhaus, H. E.
10.1101/2023.10.26.564161 — plant biology — Posted on 2023-10-27
564 A fully sequenced collection of homozygous EMS mutants for forward and reverse genetic screens in Arabidopsis thaliana
Carrere, S.; Routaboul, J.-M.; Savourat, P.; Bellenot, C.; Lopez, H.; Quiroz-Monnens, T.; Ricou, A.; Camilleri, C.; Laufs, P.; mercier, r.; Noel, L. D.
10.1101/2023.10.26.564234 — plant biology — Posted on 2023-10-27
566 MatK impacts Differential Chloroplast Translation of Ribosomal and Photosynthetic genes by limiting spliced tRNA-K(UUU) abundance
Muino, J. M.; Qu, Y.; Ruwe, H.; Maschmann, S.; Chen, W.; Zoschke, R.; Ohler, U.; Kaufmann, K.; Schmitz-Linneweber, C.
10.1101/2023.10.25.563914 — plant biology — Posted on 2023-10-27
567 A natural cyclic peptide valinomycin enhances plant innate immunity
Yoo, N.; Kang, J. E.; Kim, D.-R.; Lee, H.; Ko, D.; Kwak, Y.-S.; Chung, E.-H.
10.1101/2023.10.25.563898 — plant biology — Posted on 2023-10-27
568 Angular leaf spot in Acmella oleracea caused by a foliar nematode
Silva, M. d. F.; Faccioli, F. C.; Honorio, A. P.; Fonseca, A. R.; Boari, A. d. J.; Buonicontro, D. S.
10.1101/2023.10.24.563638 — plant biology — Posted on 2023-10-27
570 Force sensation by a Gs-coupled adhesion GPCR mediates equilibrioception by increasing vestibular hair cell membrane excitability and CNGA3 coupling
yang, z.; zhou, s.; zhang, q.; liu, w.; sun, y.; qi, j.; guan, y.; wang, m.; song, z.; sun, y.; yang, w.; Yu, X.; chai, r.; Sun, J.
10.1101/2023.10.24.563886 — physiology — Posted on 2023-10-27
572 Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma
Nejo, T.; Wang, L.; Leung, K. K.; Wang, A.; Lakshmanachetty, S.; Gallus, M.; Kwok, D. W.; Hong, C.; Chen, L. G.; Carrera, D. A.; Zhang, M. Y.; Stevers, N. O.; Maldonado, G. C.; Yamamichi, A.; Watchmaker, P.; Naik, A.; Shai, A.; Phillips, J.; Chang, S. M.; Wiita, A. P.; Wells, J. A.; Costello, J. F.; Diaz, A. A.; Okada, H.
10.1101/2023.10.26.564156 — cancer biology — Posted on 2023-10-27
573 The genetic architecture of protein stability
Faure, A. J.; Marti-Aranda, A.; Hidalgo, C.; Schmiedel, J. M.; Lehner, B.
10.1101/2023.10.27.564339 — biophysics — Posted on 2023-10-27
579 The function of ER-phagy receptors is regulated through phosphorylation-dependent ubiquitination pathways
Berkane, R.; Ho-Xuan, H.; Glogger, M.; Sanz-Martinez, P.; Brunello, L.; Glaesner, T.; Kuncha, S. K.; Holzhueter, K.; Cano-Franco, S.; Buonomo, V.; Cabrerizo-Poveda, P.; Balakrishnan, A.; Misra, M.; Juretschke, T.; Husnjak, K.; Tascher, G.; Doetsch, V.; Grumati, P.; Heilemann, M.; Stolz, A.
10.1101/2023.02.27.530364 — cell biology — Posted on 2023-10-27
580 Vagus nerve stimulation limits the germinal center B cell response via CD4+ T cell-derived acetylcholine
Kurata-Sato, I.; Mughrabi, I. T.; Rana, M.; Gerber, M.; Al-Abed, Y.; Sherry, B.; Zanos, S.; Diamond, B.
10.1101/2023.10.25.563818 — immunology — Posted on 2023-10-27
581 Development of neural circuits for social motion perception in schooling fish
Zada, D.; Schulze, L.; Yu, J.-H.; Tarabishi, P.; Napoli, J. L.; Lovett-Barron, M.
10.1101/2023.10.25.563839 — neuroscience — Posted on 2023-10-27
583 Force-sensing LPHN2 is indispensable for normal hearing and mediates MET in cochleae through Gs and CNGA3 coupling
Yang, Z.; Wang, M.-W.; Zhou, S.-H.; Song, Z.-c.; Gao, J.-R.; Liu, W.-W.; Zhang, Q.-Y.; Guan, Y.; Xu, L.; Wang, C.; Xu, Z.-G.; Yu, X.; Sun, J.-P.
10.1101/2023.10.24.563883 — physiology — Posted on 2023-10-27
584 Repression of exosome secretion by mutated β-catenin contributes to immune escape in hepatocellular carcinoma
Dantzer, C.; Vache, J.; Brunel, A.; Mahouche, I.; Raymond, A.-A.; Dupuy, J.-W.; Petrel, M.; Bioulac-Sage, P.; Perrais, D.; Dugot-Senant, N.; Verdier-Sage, M.; Bessette, B.; Billottet, C.; Moreau, V.
10.1101/2023.10.24.563805 — cancer biology — Posted on 2023-10-27
586 Comprehensive Landscape of Non-muscle Invasive Bladder Cancer Tumour Microenvironment and Prognostic value of Cancer-Associated Myofibroblasts
Canizo, C. M.; Guerrero-Ramos, F.; Perez-Escavy, M.; Lodewijk, I.; Suarez-Cabrera, C.; Morales, L.; Nunes, S. P.; Munera-Maravilla, E.; Rubio, C.; Sanchez, R.; Rodriguez-Izquierdo, M.; Martinez de Villarreal, J.; Real, F. X.; Castellano, D.; Martin-Arriscado, C.; Rodriguez-Antolin, A.; Duenas, M.; Paramio, J. M.; Martinez, V. G.
10.1101/2023.10.26.564112 — cancer biology — Posted on 2023-10-27
587 Tumor- and Nerve-Derived Axon Guidance Molecule Promotes Pancreatic Ductal Adenocarcinoma Progression and Metastasis through Macrophage Reprogramming
Thielman, N.; Funes, V.; Davuluri, S.; lbanez, H.; Sun, W.-C.; Fu, J.; Li, K.; Muth, S.; Pan, X.; Fujiwara, K.; Thomas, D.; Henderson, M.; Teh, S. S.; Zhu, Q.; Thompson, E.; Jaffee, E. M.; Kolodkin, A.; Meng, F.; Zheng, L.
10.1101/2023.10.24.563862 — cancer biology — Posted on 2023-10-27
590 MET Inhibitor Capmatinib Radiosensitizes MET Exon 14-Mutated and MET-Amplified Non-Small Cell Lung Cancer
Ramesh, S.; Cifci, A.; Javeri, S.; Minne, R.; Longhurst, C. A.; Nickel, K. P.; Kimple, R.; Baschnagel, A. M.
10.1101/2023.10.26.564232 — cancer biology — Posted on 2023-10-27
591 A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer
Zheng, J.-H.; Zhu, Y.-H.; Yang, J.; Ji, P.-X.; Zhao, R.-K.; Duan, Z.-H.; Yao, H.-F.; Jia, Q.-Y.; Yin, Y.-F.; Hu, L.-P.; Li, Q.; Jiang, S.-H.; Huo, Y.-M.; Liu, W.; Sun, Y.-W.; Liu, D.-J.
10.1101/2023.10.27.564288 — cancer biology — Posted on 2023-10-27
597 G protein activation occurs via a largely universal mechanism
Vithani, N.; Todd, T. D.; Singh, S.; Blumer, K. J.; Bowman, G. R.
10.1101/2023.10.24.563885 — biophysics — Posted on 2023-10-27
600 How osteons form: A quantitative hypothesis-testing analysis of cortical pore filling and wall asymmetry
Hegarty-Cremer, S. G.; Borggaard, X. G.; Andreasen, C. M.; van der Eerden, B. C.; Simpson, M. J.; Andersen, T. L.; Buenzli, P. R.
10.1101/2023.10.26.564273 — biophysics — Posted on 2023-10-27
602 Foundation Models Meet Imbalanced Single-Cell Data When Learning Cell Type Annotations
Alsabbagh, A. R.; Maillo Ruiz de Infante, A.; Gomez-Cabrero, D.; Kiani, N.; Khan, S. A.; Tegner, J. N.
10.1101/2023.10.24.563625 — bioinformatics — Posted on 2023-10-27
603 Venom diversity in Naja mossambica: Insights from proteomic and immunochemical analyses reveal intraspecific differences
Hus, K. K.; Buczkowicz, J.; Pietrowska, M.; Petrilla, V.; Petrillova, M.; Legath, J.; Litschka-Koen, T.; Bocian, A.
10.1101/2023.10.27.564320 — biochemistry — Posted on 2023-10-27
604 How a disordered linker in the Polycomb protein Polyhomeotic tunes phase separation and oligomerization
Gemeinhardt, T. M.; Regy, R. M.; Mendiola, A. J.; Ledterman, H. J.; Henrickson, A.; Phan, T. M.; Kim, Y. C.; Demeler, B.; Kim, C. A.; Mittal, J.; Francis, N.
10.1101/2023.10.26.564264 — biochemistry — Posted on 2023-10-27
605 Adipose tissue eQTL meta-analysis reveals the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits
Brotman, S. M.; El-Sayed Moustafa, J. S.; Guan, L.; Broadaway, K. A.; Wang, D.; Jackson, A. U.; Welch, R.; Currin, K. W.; Tomlinson, M.; Vadlamudi, S.; Stringham, H. M.; Roberts, A. L.; Lakka, T. A.; Oravilahti, A.; Fernandes Silva, L.; Narisu, N.; Erdos, M. R.; Yan, T.; Bonnycastle, L. L.; Raulerson, C. K.; Raza, Y.; Yan, X.; Parker, S. C. J.; Kuusisto, J.; Pajukanta, P.; Tuomilehto, J.; Collins, F. S.; Boehnke, M.; Love, M. I.; Koistinen, H. A.; Laakso, M.; Mohlke, K. L.; Small, K. S.; Scott, L. J.
10.1101/2023.10.26.563798 — genomics — Posted on 2023-10-27
606 AlphaMissense is better correlated with functional assays of missense impact than earlier prediction algorithms
Ljungdahl, A.; Kohani, S.; Page, N. F.; Wells, E. S.; Wigdor, E. M.; Dong, S.; Sanders, S. J.
10.1101/2023.10.24.562294 — genetics — Posted on 2023-10-27
609 The rapid diversification of Boletales is linked to Early Eocene and Mid-Miocene Climatic Optima
Wu, G.; Wu, K.; Halling, R. E.; Horak, E.; Xu, J.; Li, G.-M.; Lee, S.; Pecoraro, L.; Arzu, R. F.; Ebika, S. T. N.; Aouali, S.; Persiani, A. M.; Yorou, N. S.; Xu, X.; Feng, B.; Li, Y.-C.; Yang, Z.-L.
10.1101/2023.10.24.563795 — evolutionary biology — Posted on 2023-10-27
612 Sort-Seq: immune repertoire-based scRNA-Seq systematization
Kriukova, V. V.; Lukyanov, D. K.; Shagina, I. A.; Sharonov, G. V.; Lupyr, K. R.; Blagodatskikh, K. A.; Staroverov, D. B.; Ladell, K.; Miners, K. L.; Salnikova, M. A.; Nikolaev, R. V.; Shelikhova, L.; Maschan, M. A.; Britanova, O. V.; Franke, A.; Price, D. A.; Chudakov, D. M.
10.1101/2023.10.24.563704 — immunology — Posted on 2023-10-27
614 Divergent age-dependent conformational rearrangement within Aβ-amyloid deposits in APP23, APPPS1, and AppNL-F mice
Parvin, F.; Haglund, S.; Wegenast-Braun, B.; Jucker, M.; Saito, T.; Saido, T. C.; Nilsson, P.; Nilsson, P.; Nystrom, S.; Hammarstrom, P.
10.1101/2023.10.24.563716 — neuroscience — Posted on 2023-10-27
615 The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway
Chen, H.; Ferguson, C. J.; Mitchell, D. C.; Titus, A.; Paulo, J. A.; Hwang, A.; Lin, T.-H.; Yano, H.; Gu, W.; Song, S.-K.; Yuede, C. M.; Gygi, S. P.; Bonni, A.; Kim, A. H.
10.1101/2023.10.24.563880 — neuroscience — Posted on 2023-10-27
617 Prefrontal activity sharpens spatial sensitivity of extrastriate neurons
Vanegas, M. I.; Akbarian, A.; Clark, K. L.; Nesse, W. H.; Noudoost, B.
10.1101/2023.10.25.564095 — neuroscience — Posted on 2023-10-27
619 Waveform-based classification of dentate spikes
Santiago, R. M.; Lopes-dos-Santos, V.; Jones, E. A. A.; Huang, Y.; Dupret, D.; Tort, A. B.
10.1101/2023.10.24.563826 — neuroscience — Posted on 2023-10-27
622 Deciphering Drought Response Mechanisms: Transcriptomic Insights from Drought-Tolerant and Drought-Sensitive Wheat (Triticum aestivum L.) Cultivars
CEVHER-KESKIN, B.; YILDIZHAN, Y.; SEKMEN-CETINEL, A. H.; SEZERMAN, O. U.; OZER, B.; FAYETORBAY, R.; ONARICI, S.; TURKAN, I.; TOR, M.
10.1101/2023.10.26.563210 — plant biology — Posted on 2023-10-27
624 Pan-genome analysis of different morphotypes reveals genomic basis of Brassica oleracea domestication and differential organogenesis
Guo, N.; Wang, S.; Wang, T.; Duan, M.; Zong, M.; Miao, L.; Han, S.; Wang, G.; Liu, X.; Zhang, D.; Jiao, C.; Xu, H.; Chen, L.; Fei, Z.; Li, J.; Liu, F.
10.1101/2023.10.24.563711 — plant biology — Posted on 2023-10-27
625 Nuclear Pyruvate Dehydrogenase Complex Regulates Histone Acetylation and Transcriptional Regulation in the Ethylene Response
Shao, Z.; Bian, L.; Ahmadi, S. K.; Daniel, T. J.; Belmonte, M. A.; Burns, J. G.; Kotla, P.; Bi, Y.; Shen, Z.; Xu, S.-L.; Wang, Z.-Y.; Briggs, S. P.; Qiao, H.
10.1101/2023.10.25.564010 — plant biology — Posted on 2023-10-27
626 Force sensing GPR133 is essential for normal balance and modulates vestibular hair cell membrane excitability via Gi signaling and CNGA3 coupling
yang, z.; zhou, s.; wang, m.; ping, y.; fu, x.; zhao, r.; xiao, p.; lu, y.; zhang, q.; song, z.; xi, y.; lin, h.; zheng, y.; qin, w.; yi, f.; Yu, X.; chai, r.; Sun, J.
10.1101/2023.10.24.563882 — physiology — Posted on 2023-10-27
627 Breast Cancer Macrophage Heterogeneity and Self-renewal are Determined by Spatial Localization
Ben-Chetrit, N.; Niu, X.; Sotelo, J.; Swett, A. D.; Rajasekhar, V. K.; Jiao, M. S.; Stewart, C. M.; Bhardwaj, P.; Kottapalli, S.; Ganesan, S.; Loyher, P.-L.; Potenski, C.; Hannuna, A.; Brown, K. A.; Iyengar, N. M.; Giri, D. D.; Lowe, S. W.; Healey, J. H.; Geissmann, F.; Sagi, I.; Joyce, J. A.; Landau, D. A.
10.1101/2023.10.24.563749 — cancer biology — Posted on 2023-10-27
628 Analysis of uveal melanoma scRNA sequencing data identifies neoplastic-immune hybrid cells that exhibit metastatic potential
Anderson, A. N.; Conley, P.; Klocke, C. D.; Sengupta, S. K.; Giske, N. R.; Robinson, T. L.; Fan, Y.; Jones, J. A.; Gibbs, S. L.; Skalet, A. H.; Wu, G.; Wong, M. H.
10.1101/2023.10.24.563815 — cancer biology — Posted on 2023-10-27
629 ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
Mu, P.; Xu, Y.; Wang, Z.; Sjostrom, M.; Deng, S.; Wang, C.; Jonhson, N.; Gonzalez, J.; Li, X.; Metang, L.; Rodriguez, C.; Mukherji, A.; Wainwright, G.; Yu, X.; Yang, Y.; Barnes, S.; Hofstad, M.; Zhu, H.; Hanker, A.; He, H.; Chen, Y.; Wang, Z.; Raj, G.; Arteaga, C.; Feng, F.; Wang, Y.; Wang, T.
10.1101/2023.10.24.563645 — cancer biology — Posted on 2023-10-27
630 A Practical Approach for Targeting Structural Variants Genome-wide in Plasma Cell-free DNA
Murata, M. M.; Igari, F.; Urbanowicz, R.; Mouakkad, L.; Kim, S.; Chen, Z.; Di Vizio, D.; Posadas, E. M.; Giuliano, A. E.; Tanaka, H.
10.1101/2023.10.25.564058 — cancer biology — Posted on 2023-10-27
635 Co-transcriptional translation amplifies mRNA noise in Escherichia coli
Yang, S.; Park, S.; Son, J. B.; Kim, S.; Yi, S.; Bu, G.; Lee, N. K.
10.1101/2023.10.25.563316 — biophysics — Posted on 2023-10-27
637 Assessing mechanical agency during apical apoptotic cell extrusion
Anjum, S.; Turner, L.; Atieh, Y.; Eisenhoffer, G. T.; Davidson, L.
10.1101/2023.10.26.564227 — biophysics — Posted on 2023-10-27
638 Nonequilibrium bending fluctuations reveal microtubule mechanics in-vivo and their regulation by glutamylation
Nishi, K.; Raja, S.; Pham, A.; Freeman, R.; Roll-Mecak, A.; MacKintosh, F. C.; Schmidt, C. F.
10.1101/2023.10.26.564252 — biophysics — Posted on 2023-10-27
641 PhysiCell Studio: a graphical tool to make agent-based modeling more accessible
Heiland, R.; Bergman, D. R.; Lyons, B.; Cass, J.; L. Rocha, H.; Ruscone, M.; Noël, V.; Macklin, P.
10.1101/2023.10.24.563727 — bioinformatics — Posted on 2023-10-27
643 A time-resolved Forster resonance energy transfer assay to investigate inhibitor binding to ABCG2
Mitchell-White, J. I.; Briggs, D. A.; Mistry, S. J.; Mbiwan, H. A.; Kellam, B.; Holliday, N. D.; Briddon, S. J.; Kerr, I. D.
10.1101/2023.10.27.564323 — biochemistry — Posted on 2023-10-27
646 SART1 localizes to spindle poles forming a SART1 cap and promotes spindle pole assembly
Yokoyama, H.; Moreno-Andres, D.; Takizawa, K.; Chu, Z.; Scheufen, A.; Funabashi, T.; Ma, J.; Antonin, W.; Gruss, O.; Haramoto, Y.
10.1101/2023.10.27.564116 — cell biology — Posted on 2023-10-27
647 A viral-specific CD4+ T cell response protects female mice from Coxsackievirus B3 infection
Pattnaik, A.; Dhalech, A. H.; Condotta, S. A.; Corn, C.; Richer, M. J.; Snell, L. M.; Robinson, C. M.
10.1101/2023.10.24.563774 — immunology — Posted on 2023-10-27
649 Individual alpha frequency modulates prediction error-driven memory encoding
Jano, S. L.; Chatburn, A.; Cross, Z. R.; Schlesewsky, M.; Bornkessel-Schlesewsky, I.
10.1101/2023.10.25.564081 — neuroscience — Posted on 2023-10-27
651 Multiple steps of prion strain adaptation to a new host
Bocharova, O.; Makarava, N.; Pandit, N. P.; Molesworth, K.; Baskakov, I. V.
10.1101/2023.10.24.563743 — neuroscience — Posted on 2023-10-27
653 Dynamic layer-specific processing in the prefrontal cortex during working memory
Degutis, J. K.; Chaimow, D.; Haenelt, D.; Assem, M.; Duncan, J.; Haynes, J.-D.; Weiskopf, N.; Lorenz, R.
10.1101/2023.10.27.564330 — neuroscience — Posted on 2023-10-27
654 Effect of Human Infant Gut Microbiota on Mouse Behavior, Dendritic Complexity, and Myelination
DUBEY, H.; Roychoudhury, R.; Alex, A.; Best, C.; Liu, S.; White, A.; Carlson, A.; Azcarate-Peril, M. A.; Mansfield, L.; Knickmeyer, R. C.
10.1101/2023.10.24.563309 — neuroscience — Posted on 2023-10-27
657 Single nuclei sequencing reveals C4 photosynthesis is based on rewiring of ancestral cell identity networks
Swift, J.; Luginbuehl, L. H.; Schreier, T.; Donald, R. M.; Lee, T.; Nery, J.; Ecker, J. R.; Hibberd, J. M.
10.1101/2023.10.26.562893 — plant biology — Posted on 2023-10-27
658 Structure of PSI-LHCI from Cyanidium caldarium provides evolutionary insights into conservation and diversity of red-lineage LHCs
Kato, K.; Hamaguchi, T.; Kumazawa, M.; Nakajima, Y.; Ifuku, K.; Hirooka, S.; Hirose, Y.; Miyagishima, S.-y.; Suzuki, T.; Kawakami, K.; Dohmae, N.; Yonekura, K.; Shen, J.-R.; Nagao, R.
10.1101/2023.10.25.563911 — plant biology — Posted on 2023-10-27
660 Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Gliomas
Miller, T. E.; El Farran, C. A. K.; Couturier, C. P.; Chen, Z.; D'Antonio, J. P.; Verga, J.; Villanueva, M. A.; Castro, L. N. G.; Tong, Y. E.; Al-Saadi, T.; Chiocca, A. N.; Fischer, D. S.; Heiland, D. H.; Guerriero, J. L.; Petrecca, K.; Suva, M. L.; Shalek, A. K.; Bernstein, B. E.
10.1101/2023.10.24.563466 — cancer biology — Posted on 2023-10-27
661 Marker-based CRISPR screening reveals a MED12-p63 interaction that activates basal identity in pancreatic ductal adenocarcinoma
Maia-Silva, D.; Schier, A. C.; Skopelitis, D.; Kechejian, V.; Alpsoy, A.; Liverpool, J.; Taatjes, D. J.; Vakoc, C. R.
10.1101/2023.10.24.563848 — cancer biology — Posted on 2023-10-27
662 Ambient Temperature Bacterial Large Ribosomal Subunit Structure Enabled by Serial Femtosecond X-ray Crystallography
Tosun, B.; Rao, Y.; Destan, E.; Dao, E. H.; Ertem, F. B.; Yilmaz, M.; Yapici, I.; Gul, M.; Ayan, E.; Johnson, J. A.; Shafiei, A.; Kulakman, C.; Hayes, B.; Liang, M.; Yoon, C. H.; Su, Z.; Hunter, M. S.; Kupitz, C. J.; Poitevin, F. P.; Ciftci, H. I.; Sierra, R. G.; Gregory, S.; Milon, P.; Kurkcuoglu, O.; DeMirci, H.
10.1101/2023.10.24.563633 — biophysics — Posted on 2023-10-27
664 PDB NextGen Archive: Centralising Access to Integrated Annotations and Enriched Structural Information by the Worldwide Protein Data Bank
Choudhary, P.; Feng, Z.; Berrisford, J.; Chao, H.; Ikegawa, Y.; Peisach, E.; Piehl, D. W.; Smith, J.; Tanweer, A.; Varadi, M.; Westbrook, J. D.; Young, J. Y.; Patwardhan, A.; Morris, K. L.; Hoch, J. C.; Kurisu, G.; Velankar, S.; Burley, S. K.
10.1101/2023.10.24.563739 — bioinformatics — Posted on 2023-10-27
665 A Foundational Large Language Model for Edible Plant Genomes
Mendoza-Revilla, J.; Trop, E.; Gonzalez, L.; Roller, M.; Dalla-Torre, H.; de Almeida, B. P.; Richard, G.; Caton, J.; Lopez Carranza, N.; Skwark, M.; Laterre, A.; Beguir, K.; Pierrot, T.; Lopez, M.
10.1101/2023.10.24.563624 — genomics — Posted on 2023-10-27
670 ArcheD, a residual neural network for prediction of cerebrospinal fluid amyloid-beta from amyloid PET images
Tagmazian, A. A.; Schwarz, C.; Lange, C.; Pitkanen, E.; Vuoksimaa, E.; for the Alzheimer's Disease Neuroimaging Initiative,
10.1101/2023.06.20.545686 — neuroscience — Posted on 2023-10-27
671 Sodium myo-inositol cotransporter-1, SMIT1, promotes cardiac hypertrophy and fibrosis in pressure overloaded mouse hearts
Marino, A.; Cumps, J.; Guilbert, L.; Baufays, C.; Ginion, A.; Ferte, L.; Battault, S.; Ambroise, J.; Bearzatto, B.; Zuurbier, C. J.; Lezoualc'h, F.; Pestiaux, C.; Pyka, G.; Kerckhofs, G.; Tyteca, D.; Bouzin, C.; Bertrand, L.; Horman, S.; Beauloye, C.
10.1101/2023.10.25.564086 — cell biology — Posted on 2023-10-27
672 ER-to-Golgi trafficking via a dynamic intermediate cis-Golgi tubular network in Arabidopsis
Fougere, L.; Grison, M.; Laquel, P.; Montrazi, M.; Cordelieres, F.; Fernandez-Monreal, M.; Poujol, C.; Uemura, T.; Nakano, A.; Ito, Y.; Boutte, Y.
10.1101/2023.10.27.563925 — cell biology — Posted on 2023-10-27
673 Multi-functional ARF1 compartments serve as a hub for short-range cargo transfer to endosomes
Stockhammer, A.; Adarska, P.; Natalia, V.; Heuhsen, A.; Klemt, A.; Harel, S.; Rodilla-Ramirez, C.; Spalt, C.; Oezsoy, E.; Leupold, P.; Grindel, A.; Fox, E.; Mejedo, J. O.; Puchkov, D.; Haucke, V.; Bottanelli, F.
10.1101/2023.10.27.564143 — cell biology — Posted on 2023-10-27
674 Nanoscale imaging reveals the mechanisms of ER-to-Golgi transport via a dynamic tubular-vesicular network
Wong-Dilworth, L.; Bregu, G.; Restel, S.; Rodilla-Ramirez, C.; Ebeling, S.; Harel, S.; Leupold, P.; Grimm, J.; Lavis, L.; Bottanelli, F.; Angulo-Capel, J.; Campelo, F.
10.1101/2023.10.27.563951 — cell biology — Posted on 2023-10-27
676 Revealing Molecular Mechanisms of Early-Onset Tongue Cancer by Spatial Transcriptomics
Patysheva, M.; Kolegova, E.; Khozyainova, A.; Prostakishina, E.; Menyailo, M.; Larionova, I.; Kovalev, O.; Zavyalova, M.; Fedorova, I.; Kulbakin, D.; Polyakov, A.; Yakovleva, L.; Kropotov, M.; Sukortseva, N.; Lu, Y.; Jia, L.; Arora, R.; Choinzonov, E.; Bose, P.; Denisov, E.
10.1101/2023.10.12.562054 — cancer biology — Posted on 2023-10-27
677 A conserved ribosomal protein has entirely dissimilar structures in different organisms
Schierholz, L.; Brown, C. R.; Helena-Bueno, K.; Uversky, V. N.; Hirt, R.; Barandun, J.; Melnikov, S. V.
10.1101/2022.09.21.508910 — evolutionary biology — Posted on 2023-10-27
682 A morphogenic cascade emerges from the co-evolution of spheroid fluidization and fracturing of multicellular barriers
Wu, S. K.; Ho, C. Z.; Sun, F.; Lou, Y.; Huang, C. B.-X.; Xiao, J.; Shagirov, M.; Yow, I.; Chin, J. F. L.; Verma, S.; Yap, A.; Lin, Y.; Hiraiwa, T.; Low, B. C.
10.1101/2023.09.25.559247 — cell biology — Posted on 2023-10-27
683 Seasonal dynamics of the microbial methane filter in the water column of a eutrophic coastal basin
Venetz, J.; Zygadlowska, O. M.; Dotsios, N.; Wallenius, A. J.; van Helmond, N. A. G. M.; Lenstra, W. K.; Slomp, C. P.; Jetten, M. S. M.; Veraart, A. J.
10.1101/2023.10.26.563584 — microbiology — Posted on 2023-10-27
686 Cryo-electron tomography reveals the structural diversity of cardiac proteins in their cellular context
Woldeyes, R. A.; Nishiga, M.; Vander Roest, A. S.; Engel, L.; Giri, P.; Montenegro, G. C.; Wu, A. C.; Dunn, A. R.; Spudich, J. A.; Bernstein, D.; Schmid, M. F.; Wu, J. C.; Chiu, W.
10.1101/2023.10.26.564098 — biophysics — Posted on 2023-10-26
687 KIF1C activates and extends dynein movement through the FHF cargo adaptor
Ali, F. A.; Zwetsloot, A. J.; Stone, C. E.; Morgan, T. E.; Wademan, R. F.; Carter, A. P.; Straube, A.
10.1101/2023.10.26.564242 — cell biology — Posted on 2023-10-26
689 Lack of chromokinesin Klp-19 creates a more rigid midzone and affects force transmission during anaphase in C. elegans
Zimyanin, V.; Magaj, M. M.; Yu, C.-H.; Gibney, T. V.; Mustafa, B.; Horton, X.; Siller, K.; Cueff, L.; Bouvrais, H.; Pecreaux, J.; Needleman, D.; Redemann, S.
10.1101/2023.10.26.564275 — cell biology — Posted on 2023-10-26
690 Senescence of endplate osteoclasts induces sensory innervation and spinal pain
Pan, D.; Benkato, K. G.; Han, X.; Zheng, J.; Kumar, V.; Wan, M.; Zheng, J.; Cao, X.
10.1101/2023.10.26.564218 — cell biology — Posted on 2023-10-26
691 Deep multi-omic profiling reveals extensive mitochondrial remodeling driven by glycemia in early diabetic kidney disease
Granata, C.; Thallas-Bonke, V.; Caruana, N. j.; Huynh, K.; Qin, C. X.; Laskowski, A.; Snelson, M.; Anthonisz, J.; Jap, E.; Ramm, G.; Cooper, M. E.; Meikle, P.; Stroud, D. A.; Ritchie, R. H.; Coughlan, M. T.
10.1101/2023.10.26.564228 — cell biology — Posted on 2023-10-26
692 Sequence-based machine learning reveals 3D genome differences between bonobos and chimpanzees
Brand, C. M.; Kuang, S.; Gilbertson, E. N.; McArthur, E.; Pollard, K. S.; Webster, T. H.; Capra, J. A.
10.1101/2023.10.26.564272 — genomics — Posted on 2023-10-26
694 The human developing cerebral cortex is characterized by an increased de novo expression of lncRNAs in excitatory neurons
Morales-Vicente, D. A.; Tahira, A. C.; Woellner-Santos, D.; Amaral, M. S.; Berzoti-Coelho, M. G.; Verjovski-Almeida, S.
10.1101/2023.10.26.564246 — evolutionary biology — Posted on 2023-10-26
695 Phylogenomics reveals a gene flow history of reverse colonization
Aoki, D.; Senzaki, M.; Ando, H.; Odaya, Y.; Heim, W.; Kitazawa, M.; Tom, W.; Trense, D.; Bastardot, M.; Fukuda, A.; Takahashi, M.; Kondo, N.
10.1101/2023.09.27.559751 — evolutionary biology — Posted on 2023-10-26
696 Enhancing Escherichia coli Abiotic Stress Resistance through Ornithine Lipid Formation
Bedoya-Perez, L. P.; Aguilar-Vera, A.; Sanchez-Perez, M.; Utrilla, J.; Sohlenkamp, C.
10.1101/2023.06.13.544863 — synthetic biology — Posted on 2023-10-26
699 The origin and maintenance of supergenes contributing to ecological adaptation in Atlantic herring
Jamsandekar, M.; Ferreira, M. S.; Pettersson, M. E.; Farrell, E.; Davis, B. W.; Andersson, L.
10.1101/2023.10.23.562618 — evolutionary biology — Posted on 2023-10-26
700 Cortical network and projection neuron types that articulate serial order in a skilled motor behavior
Li, Y.; An, X.; Qian, Y.; Xu, X. H.; Zhao, S.; Mohan, H.; Bachschmid-Romano, L.; Brunel, N.; Whishaw, I. Q.; Huang, Z. J.
10.1101/2023.10.25.563871 — neuroscience — Posted on 2023-10-26
701 Neural-circuit basis of song preference learning in fruit flies
Imoto, K.; Ishikawa, Y.; Aso, Y.; Funke, J.; Tanaka, R.; Kamikouchi, A.
10.1101/2023.10.24.563693 — neuroscience — Posted on 2023-10-26
702 Integrating brainstem and cortical functional architectures
Hansen, J. Y.; Cauzzo, S.; Singh, K.; Garcia-Gomar, M. G.; Shine, J. M.; Bianciardi, M.; Misic, B.
10.1101/2023.10.26.564245 — neuroscience — Posted on 2023-10-26
703 Turn-On Protein Switches for Controlling Actin Binding in Cells
Effiong, U. M.; Khairandish, H.; Ramirez-Velez, I.; Wang, Y.; Belardi, B.
10.1101/2023.10.26.561921 — synthetic biology — Posted on 2023-10-26
704 Integrating population-level and cell-based signatures for drug repositioning
He, C.; Xu, Y.; Zhou, Y.; Fan, J.; Cheng, C.; Meng, R.; Gamazon, E. R.; Zhou, D.
10.1101/2023.10.25.564079 — bioinformatics — Posted on 2023-10-26
707 Immune landscape of tertiary lymphoid structures in hepatocellular carcinoma (HCC) treated with neoadjuvant immune checkpoint blockade
Shu, D. H.; Ho, W. J.; Kagohara, L. T.; Girgis, A.; Shin, S. M.; Danilova, L.; Lee, J. W.; Sidiropoulos, D. N.; Mitchell, S.; Munjal, K.; Howe, K.; Bendinelli, K. J.; Qi, H.; Mo, G.; Montagne, J.; Leatherman, J. M.; Lopez-Vidal, T. Y.; Zhu, Q.; Huff, A. L.; Yuan, X.; Hernandez, A.; Coyne, E. M.; Zaidi, N.; Zabransky, D. J.; Engle, L. L.; Ogurtsova, A.; Baretti, M.; Laheru, D.; Durham, J. N.; Wang, H.; Anders, R.; Jaffee, E. M.; Fertig, E. J.; Yarchoan, M.
10.1101/2023.10.16.562104 — immunology — Posted on 2023-10-26
709 Digital profiling of cancer transcriptomes from histology images with grouped vision attention
Zheng, Y.; Pizurica, M.; Carrillo-Perez, F.; Noor, H.; Yao, W.; Wohlfart, C.; Marchal, K.; Vladimirova, A.; Gevaert, O.
10.1101/2023.09.28.560068 — bioinformatics — Posted on 2023-10-26
711 Assessing Lanthanide-Dependent Methanol Dehydrogenase Activity: The Assay Matters
Phi, M. T.; Singer, H.; Zah, F.; Haisch, C.; Schneider, S.; den Camp, H. J. M.; Daumann, L. J.
10.1101/2023.10.26.563981 — biochemistry — Posted on 2023-10-26
712 Non-modular Fatty Acid Synthases Yield Unique Acylation in Ribosomal Peptides
Ren, H.; Huang, C.; Pan, Y.; Cui, H.; Dommaraju, S. R.; Mitchell, D. A.; Zhao, H.
10.1101/2023.10.25.564083 — biochemistry — Posted on 2023-10-26
713 Chemoproteomics identifies proteoform-selective caspase-2 inhibitors
Castellon, J. O.; Ofori, S.; Armenta, E.; Burton, N.; Boatner, L. M.; Takayoshi, E. E.; Faragalla, M.; Zhou, A.; Tran, K.; Shek, J.; Yan, T.; Desai, H. S.; Backus, K. M.
10.1101/2023.10.25.563785 — biochemistry — Posted on 2023-10-26
715 Genome dilution by cell growth drives starvation-like proteome remodeling in mammalian and yeast cells
Lanz, M. C.; Zhang, S.; Swaffer, M. P.; Hernandez Götz, L.; McCarty, F.; Ziv, I.; Jarosz, D. F.; Elias, J. E.; Skotheim, J. M.
10.1101/2023.10.16.562558 — cell biology — Posted on 2023-10-26
718 Is developmental plasticity triggered by DNA methylation changes in the invasive cane toad (Rhinella marina)?
Yagound, B.; Sarma, R. R.; Edwards, R. J.; Richardson, M. F.; Lopez, C. M. R.; Crossland, M. R.; Brown, G. P.; DeVore, J. L.; Shine, R.; Rollins, L. A.
10.1101/2023.10.26.564158 — molecular biology — Posted on 2023-10-26
719 Seasonal dynamics of the microbial methane filter in the water column of a eutrophic coastal basin
Venetz, J.; Zygadlowska, O. M.; Dotsios, N.; Wallenius, A. J.; van Helmond, N. A. G. M.; Lenstra, W. K.; Slomp, C. P.; Jetten, M. S. M.; Veraart, A. J.
10.1101/2023.10.26.563584 — microbiology — Posted on 2023-10-26
720 Transcription-driven DNA supercoiling activates bacterial chromatin at a distance
Figueroa-Bossi, N.; Fernandez-Fernandez, R.; Kerboriou, P.; Bouloc, P.; Casadesus, J.; Sanchez-Romero, M.-A.; Bossi, L.
10.1101/2023.10.26.564199 — microbiology — Posted on 2023-10-26
721 The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth
Franklin, A.; Layton, A. J.; Mize, T.; Salgueiro, V. C.; Sullivan, R.; Benedict, S. T.; Gurcha, S. S.; Anso, I.; Besra, G. S.; Banzhaf, M.; Lovering, A. L.; Williams, S. J.; Guerin, M. E.; Scott, N. E.; Prados-Rosales, R.; Lowe, E. C.; Moynihan, P. J.
10.1101/2023.10.26.563968 — microbiology — Posted on 2023-10-26
725 Biosynthesis- and Metabolomics-guided discovery of antimicrobial cyclopeptides against drug-resistant clinical isolates
Cheng, Z.; He, B.-B.; Lei, K.; Gao, Y.; Shi, Y.; Zhong, Z.; Liu, H.; Liu, R.; Zhang, H.; Wu, S.; Zhang, W.; Tang, X.; Li, Y.-X.
10.1101/2023.10.26.563470 — biochemistry — Posted on 2023-10-26
726 3-O-methyltolcapone and Its Lipophilic Analogues are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity
Poonsiri, T.; dell Accantera, D.; Loconte, V.; Casnati, A.; Cervoni, L.; Arcovito, A.; Benini, S.; Ferrari, A.; Cipolloni, M.; Cacioni, E.; De Franco, F.; Giacche, N.; Rinaldo, S.; Folli, C.; Sansone, F.; Berni, R.; Cianci, M.
10.1101/2023.10.25.563927 — biochemistry — Posted on 2023-10-26
729 ASSESSING TARGET SPECIFICITY OF THE SMALL MOLECULE INHIBITOR MARIMASTAT TO SNAKE VENOM TOXINS: A NOVEL APPLICATION OF THERMAL PROTEOME PROFILING
Smith, C. F.; Modahl, C. M.; Ceja-Galindo, D.; Larson, K. Y.; Maroney, S. P.; Bahrabadi, L.; Brandehoff, N. P.; Perry, B. W.; McCabe, M. C.; Petras, D.; Lomonte, B.; Calvete, J. J.; Castoe, T. A.; Mackessy, S. P.; Hansen, K. C.; Saviola, A. J.
10.1101/2023.10.25.564059 — biochemistry — Posted on 2023-10-26
731 Role of canonical and non-canonical cAMP Sources in CRHR2α-dependent Signaling
Armando, N. G.; dos Santos Claro, P. A.; Fuertes, M.; Arzt, E. S.; Silberstein, S.
10.1101/2023.10.26.563777 — molecular biology — Posted on 2023-10-26
734 Ubiquitous purine sensor modulates diverse signal transduction pathways in bacteria
Monteagudo-Cascales, E.; Gumerov, V. M.; Fernandez, M.; Matilla, M. A.; Gavira, J. A.; Jouline, I.; Krell, T.
10.1101/2023.10.26.564149 — microbiology — Posted on 2023-10-26
736 Reduced Monocyte Proportions and Responsiveness in Convalescent COVID-19 Patients
Ravkov, E.; Williams, E. S. C. P.; Elgort, M.; Spivak, A.; Barker, A. P.; Planelles, V.; Delgado, J.; Lin, L.; Hanley, T.
10.1101/2023.10.25.563806 — immunology — Posted on 2023-10-26
737 A deep learning framework for predicting the neutralizing activity of COVID-19 therapeutics and vaccines against evolving SARS-CoV-2 variants
Matson, R. P.; Comba, I. Y.; Silvert, E.; Niesen, M. J.; Murugadoss, K.; Padwardhan, D.; Suratekar, R.; Goel, E.-G.; Poelaert, B. J.; Wan, K.; Brimacombe, K. R.; Venkatakrishnan, A.; Soundararajan, V.
10.1101/2023.10.24.563847 — immunology — Posted on 2023-10-26
738 Early antiviral CD4 and CD8 T cell responses are associated with upper respiratory tract clearance of SARS-CoV-2
Ramirez, S. I.; Lopez, P. G.; Faraji, F.; Parikh, U. M.; Heaps, A.; Ritz, J.; Moser, C.; Eron, J. J.; Wohl, D. A.; Currier, J. S.; Daar, E. S.; Greninger, A. L.; Klekotka, P.; Grifoni, A.; Weiskopf, D.; Sette, A.; Peters, B.; Hughes, M. D.; Chew, K. W.; Smith, D. M.; Crotty, S.; ACTIV-2/A5401 Study Team,
10.1101/2023.10.25.564014 — immunology — Posted on 2023-10-26
739 Discovery of a novel inhibitor of macropinocytosis with antiviral activity
Porebski, B.; Christ, W.; Corman, A.; Haraldsson, M.; Barz, M.; Lidemalm, L.; Haggblad, M.; Illmain, J.; Wright, S.; Murga, M.; Schlegel, J.; Sezgin, E.; Bhabha, G.; Lauschke, V. M.; Lafarga, M.; Klingstrom, J.; Huhn, D.; Fernandez-Capetillo, O.
10.1101/2023.10.25.563967 — pharmacology and toxicology — Posted on 2023-10-26
740 Deep Batch Active Learning for Drug Discovery
Bailey, M.; Moayedpour, S.; Li, R.; Corrochano-Navarro, A.; Kötter, A.; Kogler-Anele, L.; Riahi, S.; Grebner, C.; Hessler, G.; Matter, H.; Bianciotto, M.; Mas, P.; Bar-Joseph, Z.; Jager, S.
10.1101/2023.07.26.550653 — bioinformatics — Posted on 2023-10-26
743 Phylogenomics, biogeography, and trait evolution of the Boletaceae (Boletales, Agaricomycetes, Basidiomycota)
Tremble, K.; Henkel, T.; Bradshaw, A.; Domnauer, C.; Brown, L.; Furci, G.; Tham, L. X.; Aime, C.; Moncalvo, J.-M.; Dentinger, B.
10.1101/2023.10.18.563010 — evolutionary biology — Posted on 2023-10-26
744 Diatom pyrenoids are encased in a protein shell that enables efficient CO2 fixation
Shimakawa, G.; Demulder, M.; Flori, S.; Kawamoto, A.; Tsuji, Y.; Nawaly, H.; Tanaka, A.; Tohda, R.; Ota, T.; Matsui, H.; Morishima, N.; Okubo, R.; Wietrzynski, W.; Lamm, L.; Righetto, R. D.; Uwizeye, C.; Gallet, B.; Jouneau, P.-H.; Gerle, C.; Kurisu, G.; Finazzi, G.; Engel, B. D.; Matsuda, Y.
10.1101/2023.10.25.564039 — cell biology — Posted on 2023-10-26
745 Cross-platform comparison of highly-sensitive immunoassays for inflammatory markers in a COVID-19 cohort
Abe, K.; Beer, J. C.; Nguyen, T.; Ariyapala, I. S.; Holmes, T. H.; Feng, W.; Zhang, B.; Kuo, D.; Luo, Y.; Ma, X.-J.; Maecker, H. T.
10.1101/2023.10.24.563866 — immunology — Posted on 2023-10-26
746 Endothelial cell-derived, secreted long non-coding RNAs Gadlor1 and Gadlor2 aggravate pathological cardiac remodeling via intercellular crosstalk
Keles, M.; Grein, S.; Froese, N.; Wirth, D.; Trogisch, F. A.; Wardman, R.; Hemanna, S.; Weinzierl, N.; Reiners-Koch, P.-S.; Uhlig, S.; Lomada, S.; Dittrich, G. M.; Szaroszyk, M.; Haustein, R.; Hegermann, J.; Martin Garrido, A.; Bauersachs, J.; Frank, D.; Frey, N.; Bieback, K.; Cordero, J.; Dobreva, G.; Wieland, T.; Heineke, J.
10.1101/2022.09.19.508486 — systems biology — Posted on 2023-10-26
747 Porphyrin overdrive rewires pan-cancer cell metabolism
Adapa, S. R.; Hunter, G.; Amin, N.; Marinescu, C.; Borsky, A.; Sagatys, E.; Sebti, S.; Reuther, G.; Ferreira, G.; Jiang, R.
10.1101/2022.02.18.481061 — cancer biology — Posted on 2023-10-26
754 A spatial map of hepatic mitochondria uncovers functional heterogeneity shaped by nutrient-sensing signaling
Kang, S. W. S.; Cunningham, R. P.; Miller, C. B.; Brown, L. A.; Cultraro, C. M.; Harned, A.; Narayan, K.; Hernandez, J.; Jenkins, L. M.; Lobanov, A.; Cam, M.; Porat-Shliom, N.
10.1101/2023.04.13.536717 — cell biology — Posted on 2023-10-26
756 A bivalent Adenovirus-Vectored Vaccine induces a measurable humoral response, but does not protect cynomolgus macaques against a lethal challenge with Sudan virus
van Tol, S.; Fletcher, P.; Feldmann, F.; Mukesh, R. K.; Port, J. R.; Gallogly, S.; Schulz, J. E.; Roderick, J. F.; Makinson, R.; Carmody, A.; Myers, L.; Lovaglio, J.; Smith, B. J.; Okumura, A.; Shaia, C.; Saturday, G.; Marzi, A.; Munster, V. J.; van Doremalen, N.
10.1101/2023.10.20.563337 — microbiology — Posted on 2023-10-26
757 Leucine alleviates cytokine storm syndrome by regulating macrophage polarization via the mTORC1/LXRα signaling pathway
Yan, H.; Liu, Y.; Li, X.; Yu, B.; He, J.; Mao, X.; Yu, J.; Huang, Z.; Luo, Y.; Luo, J.; Wu, A.; Chen, D.
10.1101/2023.06.21.546014 — immunology — Posted on 2023-10-26
759 Concussion-related disruptions to hub connectivity in the default mode network are related to symptoms and cognition
Bouchard, H. C.; Higgins, K. L.; Amadon, G. K.; Laing, J. M.; Maerlender, A.; Al-Momani, S.; Neta, M.; Savage, C. R.; Schultz, D. H.
10.1101/2023.03.07.531551 — neuroscience — Posted on 2023-10-26
760 Engineered yeast cells simulating CD19+ cancers to control CAR T cell activation
Deichmann, M.; Schiesaro, G.; Ramanathan, K.; Zeeberg, K. V. W.; Koefoed, N. M. T.; Ormhoj, M.; Friis, R. U. W.; Gill, R. T.; Hadrup, S. R.; Jensen, E. D.; Jensen, M. K.
10.1101/2023.10.25.563929 — synthetic biology — Posted on 2023-10-26
762 Integration of variant annotations using deep set networks boosts rare variant association genetics
Clarke, B.; Holtkamp, E.; Ozturk, H.; Muck, M.; Wahlberg, M.; Meyer, K.; Munzlinger, F.; Brechtmann, F.; Holzlwimmer, F. R.; Gagneur, J.; Stegle, O.
10.1101/2023.07.12.548506 — bioinformatics — Posted on 2023-10-26
764 Ice nucleation proteins self-assemble into large fibres to trigger freezing at near 0 ℃
Hansen, T.; Lee, J. C.; Reicher, N.; Ovadia, G.; Guo, S.; Guo, W.; Liu, J.; Braslavsky, I.; Rudich, Y.; Davies, P. L.
10.1101/2023.08.03.551873 — biochemistry — Posted on 2023-10-26
770 Characterization of Tryptophan Oxidation Affecting D1 Degradation by FtsH in the Photosystem II Quality Control of Chloroplasts
Kato, Y.; Kuroda, H.; Ozawa, S.-I.; Saito, K.; Dogra, V.; Scholz, M.; Zhang, G.; de Vitry, C.; Ishikita, H.; Kim, C.; Hippler, M.; Takahashi, Y.; Sakamoto, W.
10.1101/2023.04.20.537607 — plant biology — Posted on 2023-10-26
771 Universal inverse modelling of point spread functions for SMLM localization and microscope characterization
Liu, S.; Chen, J.; Hellgoth, J.; Mueller, L.-R.; Ferdman, B.; Karras, C.; Xiao, D.; Lidke, K. A.; Heintzmann, R.; Shechtman, Y.; Li, Y.; Ries, J.
10.1101/2023.10.26.564064 — biophysics — Posted on 2023-10-26
773 Functional Tissue Units in the Human Reference Atlas
Bidanta, S.; Börner, K.; Herr, B. W.; Nagy, M.; Gustilo, K. S.; Bajema, R.; Maier, L.; Molontay, R.; Weber, G.
10.1101/2023.10.16.562593 — bioinformatics — Posted on 2023-10-26
775 A Spatiotemporal and Machine-Learning Platform Accelerates the Manufacturing of hPSC-derived Esophageal Mucosa
Yang, Y.; McCullough, C. G.; Seninge, L.; Guo, L.; Kwon, W.-J.; Zhang, Y. Z.; Li, N. Y.; Gaddam, S.; Pan, C.; Zhen, H.; Torkelson, J.; Glass, I.; Charville, G.; Que, J.; Stuart, J.; Ding, H.; Oro, A. E.
10.1101/2023.10.24.563664 — developmental biology — Posted on 2023-10-26
777 Energy metabolism modulates the regulatory impact of activators on gene expression
Qiao, S.; Bernasek, S.; Gallagher, K. D.; Yamada, S.; Bagheri, N.; Amaral, L. A. N.; Carthew, R. W.
10.1101/2023.10.24.563842 — developmental biology — Posted on 2023-10-26
781 SCF cyclin F - EXO1 axis controls cell cycle dependent execution of double strand break repair
Yang, H.; Fouad, S.; Smith, P.; Bae, E. Y.; Ji, Y.; Ess, A. V.; Buffa, F. M.; Fischer, R.; Vendrell, I.; Kessler, B. M.; D'Angiolella, V.
10.1101/2023.10.26.562393 — cell biology — Posted on 2023-10-26
786 A large-scale volumetric correlated light and electron microscopy study localizes Alzheimer's disease-related molecules in the hippocampus
Han, X.; Wang, S.; Sanchez, M.; Aggarwal, S.; Schalek, R.; Meirovitch, Y.; Lin, Z.; Wu, Y.; Aly, F.; Bay, S.; Delatour, B.; Lafaye, P.; Pfister, H.; Wei, D.; Ploegh, H.; Lichtman, J.
10.1101/2023.10.24.563674 — neuroscience — Posted on 2023-10-26
787 Targeting cancer with small molecule pan-KRAS degraders
Popow, J.; Farnaby, W.; Gollner, A.; Kofink, C.; Fischer, G.; Wurm, M.; Zollman, D.; Wijaya, A.; Mischerikow, N.; Hasenoehrl, C.; Prokofeva, P.; Arnhof, H.; Arce-Solano, S.; Bell, S.; Boeck, G.; Diers, E.; Frost, A. B.; Goodwin-Tindall, J.; Karolyi-Oezguer, J.; Khan, S.; Klawatsch, T.; Koegl, M.; Kousek, R.; Kratochvil, B.; Kropatsch, K.; Lauber, A. A.; McLennan, R.; Olt, S.; Peter, D.; Petermann, O.; Roessler, V.; Stolt-Bergner, P.; Strack, P.; Strauss, E.; Trainor, N.; Vetma, V.; Whitworth, C.; Zhong, S.; Quant, J.; Weinstabl, H.; Küster, B.; Ettmayer, P.; Ciulli, A.
10.1101/2023.10.24.563163 — pharmacology and toxicology — Posted on 2023-10-26
788 fhl2b expression ameliorates muscular dystrophy
Dennhag, N.; Kahsay, A.; Nissen, I.; Chermenina, M.; Nord, H.; Liu, J.; Arner, A.; Liu, J.-X.; Backman, L. J.; Remeseiro, S.; von Hofsten, J.; Pedrosa Domellof, F.
10.1101/2023.10.26.563896 — cell biology — Posted on 2023-10-26
791 Spatial control of the APC/C ensures the rapid degradation of Cyclin B1
Cirillo, L.; Young, R.; Veerapathiran, S.; Roberti, A.; Martin, M. S.; Abubacar, A.; Perosa, C.; Coates, C.; Muhammad, R.; Roumeliotis, T. I.; Choudhary, J.; Alfieri, C.; Pines, J.
10.1101/2023.10.26.564157 — cell biology — Posted on 2023-10-26
792 Interactions of netrin-1 through its glycosylation sites immobilize Deleted in Colorectal Cancer (DCC) by favoring its constitutive clustering
URIOT, K.; BLANC, O.; AUDUGE, N.; FAKLARIS, O.; CHAVEROT, N.; BLOCH, E.; BORGHI, N.; COPPEY-MOISAN, M.; GIRARD, P. P.
10.1101/2023.10.26.563740 — cell biology — Posted on 2023-10-26
795 A Protein Blueprint of the Diatom CO2-Fixing Organelle
Nam, O.; McKenzie, C.; Dowle, A.; Dowson, M.; Barrett, J.; Mackinder, L.
10.1101/2023.10.26.564148 — cell biology — Posted on 2023-10-26
798 Systems genetics identifies the association between Enc1 and cognitive function in the hippocampus
He, H.; Tao, R.; Han, Z.; Yin, Q.; Pan, S.; Lu, L.; Bajpai, A. K.; Mi, J.; Qi, D.; Li, H.; Xu, F.
10.1101/2023.10.23.563569 — genetics — Posted on 2023-10-26
799 The stress-induced lincRNA JUNI is a critical factor for cancer cell survival whose interactome is a prognostic signature in clear cell renal cell carcinoma
Kumar, V.; Sabate-Cadenas, X.; Soni, I.; Stern, E.; Vias, C.; Ginsberg, D.; Roma-Mateo, C.; Pulido, R.; Dodel, M.; Mardakheh, F. K.; Ben-Dov, I. Z.; Shkumatava, A.; Shaulian, E.
10.1101/2023.10.23.563579 — cell biology — Posted on 2023-10-26
800 Increased spontaneous Ca2+ activity in Cardiac Purkinje cells after myocardial infarction; A consequence of a dramatic shift of SERCA isoforms as potential adaptation to acute ischemia?
Stuyvers, B. D.; Boyden, P. A.; Amin, R.; Wiede, L. L.; Dore, J.; ter Keurs, H. E.; Dun, W.; Guo, Y.; Haissaguerre, M.; Hocini, M.; Brette, F.; Bernus, O.; Chaigne, S.; Loyer, V.; Naulin, J.; Quesson, B.; Alafiatayo, A.; Benoukraf, T.
10.1101/2023.10.23.563678 — cell biology — Posted on 2023-10-26
801 Pharmacologically inducing regenerative cardiac cells by small molecule drugs
Zhou, W.; He, K.; Wang, C.; Wang, P.; Wang, D.; Wang, B.; Geng, H.; Lian, H.; Ma, T.; Nie, Y.; Ding, S.
10.1101/2023.10.24.563872 — cell biology — Posted on 2023-10-26
802 Helminth infection driven gastrointestinal hypermotility is independent of eosinophils and mediated by alterations in smooth muscle instead of enteric neurons
Harris, N.; Barry, K.; Coakley, G.; Moyat, M.; Daunt, C.; Zaini, A.; Wickramasinghe, L.; Yumnam, B.; Camberis, M.; Le Gros, G.; Perdijk, O.; Foong, J.; Bornstein, J.; Marsland, B.
10.1101/2023.10.23.563519 — immunology — Posted on 2023-10-26
804 Platelet proteo-transcriptomic profiling validates mediators of thrombosis and proteostasis in patients with myeloproliferative neoplasms
Kelliher, S.; Gamba, S.; Weiss, L.; Shen, Z.; Marchetti, M.; Schieppati, F.; Scaife, C.; Madden, S.; Bennett, K.; Fortune, A.; Maung, S.; Fay, M.; Ni Ainle, F.; Maguire, P.; Falanga, A.; Kevane, B.; Krishnan, A.
10.1101/2023.10.23.563619 — pathology — Posted on 2023-10-26
807 Accelerated drug resistant variant discovery with an enhanced, scalable mutagenic base editor platform
Dorighi, K.; Zhu, A.; Fortin, J.-P.; Lo, J. H.-H.; Sudhamsu, J.; Durinck, S.; Callow, M.; Foster, S.; Haley, B.
10.1101/2023.10.25.564011 — molecular biology — Posted on 2023-10-26
810 From disturbances to nonlinear fitness and back.
Tuljapurkar, S. D.; Jaggi, H.; Gascoigne, S. J. L.; Zuo, W.; Kajin, M.; Salguero-Gomez, R.
10.1101/2023.10.20.563360 — ecology — Posted on 2023-10-26
811 Elevated epigenetic age in wild compared to lab-raised house mice
Hanski, E.; Joseph, S.; Raulo, A.; Wanelik, K.; O'Toole, A.; Knowles, S. C. L.; Little, T. J.
10.1101/2023.10.25.563913 — molecular biology — Posted on 2023-10-26
812 M6A reduction relieves FUS-associated ALS granules
Di Timoteo, G.; Giuliani, A.; Setti, A.; Biagi, M. C.; Lisi, M.; Grandioso, A.; Mariani, D.; Castagnetti, F.; Perego, E.; Zappone, S.; Vicidomini, G.; Rotili, D.; Sabatelli, M.; Lattante, S.; Bozzoni, I.
10.1101/2023.10.25.563954 — molecular biology — Posted on 2023-10-26
813 Establishing CRISPR-Cas9 in the sexually dimorphic moss, Ceratodon purpureus.
Tavernier, E.-K. G.; Lockwood, E.; Perroud, P.-F.; Nogue, F.; McDaniel, S. F.
10.1101/2023.10.25.562971 — molecular biology — Posted on 2023-10-26
814 Sprr1 and miR-130b contribute to the senescence-like phenotype in aging
Hong, J. Y.; Nam, H. J.; Ji, H.; Kim, Y. Y.; Hyun, M.; Park, H. J.; Bae, S. M.; McCrea, P. D.
10.1101/2023.10.25.563779 — molecular biology — Posted on 2023-10-26
815 Structure and assembly of a bacterial gasdermin pore
Johnson, A. G.; Mayer, M. L.; Schaefer, S. L.; McNamara-Bordewick, N. K.; Hummer, G.; Kranzusch, P. J.
10.1101/2023.04.20.537723 — microbiology — Posted on 2023-10-26
816 Widespread fungal-bacterial competition for magnesium enhances antibiotic resistance
Hsieh, Y.-Y. P.; Sun, W. W.; Young, J. M.; Cheung, R.; Hogan, D. A.; Dandekar, A. A.; Malik, H. S.
10.1101/2023.10.25.563990 — microbiology — Posted on 2023-10-26
818 Differentiation of hypervirulent and classical Klebsiella pneumoniae with acquired drug resistance
Russo, T. A.; Alvarado, C. L.; Davies, C. J.; Drayer, Z. J.; Carlino-MacDonald, U.; Hutson, A.; Luo, T. L.; Martin, M. J.; Corey, B. W.; Moser, K. A.; Rasheed, J. K.; Halpin, A. L.; McGann, P.; Lebreton, F.
10.1101/2023.06.30.547231 — microbiology — Posted on 2023-10-26
819 Streptococcus pyogenes Cas9 ribonucleoprotein delivery for efficient, rapid and marker-free gene editing in Trypanosoma and Leishmania
Asencio, C.; Herve, P.; Morand, P.; Oliveres, Q.; Morel, C. A.; Prouzet-Mauleon, V.; Biran, M.; Monic, S.; Bonhivers, M.; Robinson, D. R.; Ouellette, M.; Riviere, L.; Bringaud, F.; Tetaud, E.
10.1101/2023.10.25.563974 — microbiology — Posted on 2023-10-26
820 Mycobacterial DnaQ is an Alternative Proofreader Ensuring DNA Replication Fidelity
Deng, M.-Z.; Liu, Q.; Cui, S.-J.; Fu, H.; Gan, M.; Xu, Y.-Y.; Cai, X.; Sha, W.; Zhao, G.-P.; Fortune, S. M.; Lyu, L.-D.
10.1101/2023.10.24.563508 — microbiology — Posted on 2023-10-26
821 Recombinant chimeric Horsepox Virus (TNX-801) is attenuated relative to Vaccinia Virus Strains in Human Primary Cell Lines and in Immunocompromised Mice
Trefry, S.; Raney, C.; Cregger, A.; Martinez, N.; Layton, B.; Enamorado, R.; Gohegan, D.; Moulaei, T.; Ziolkowska, N.; Geobel, S.; Lederman, S.; Bavari, S.; Nasar, F.
10.1101/2023.10.25.564033 — microbiology — Posted on 2023-10-26
822 Genome sequences of equine influenza A subtype H3N8 viruses by long read sequencing and functional characterization of the PB1-F2 virulence factor of A/equine/Paris/1/2018
Kleij, L.; Bruder, E.; Raoux-Barbot, D.; Lejal, N.; Nevers, Q.; Deloisy, C.; Da Costa, B.; Legrand, L.; Barrey, E.; Chenal, A.; Pronost, S.; Delmas, B.; Dhorne-Pollet, S.
10.1101/2023.10.25.563963 — microbiology — Posted on 2023-10-26
826 Gene expression analyses reveal differences in children's response to malaria according to their age
Tebben, K.; Yirampo, S.; Coulibaly, D.; Kone, A. K.; Laurens, M. B.; Stucke, E.; Dembele, A.; Tolo, Y.; Traore, K.; Niangaly, A.; Berry, A. A.; Kouriba, B.; Plowe, C. V.; Lyke, K. E.; Takala-Harrison, S.; Travassos, M. A.; Serre, D.
10.1101/2023.10.24.563751 — microbiology — Posted on 2023-10-26
827 A non-canonical Arp2/3 complex is essential for Plasmodium DNA segregation and transmission of malaria.
Hentzschel, F.; Jewanski, D.; Sokolowski, Y.; Agarwal, P.; Kraeft, A.; Hildenbrand, K.; Dorner, L. P.; Singer, M.; Frischknecht, F.; Marti, M.
10.1101/2023.10.25.563799 — microbiology — Posted on 2023-10-26
828 The prevalence of Fusobacterium nucleatum subspecies in the oral cavity stratifies by local health status
Krieger, M.; AbdelRahman, Y. M.; Choi, D.; Palmer, E. A.; Yoo, A.; McGuire, S.; Kreth, J.; Merritt, J.
10.1101/2023.10.25.563997 — microbiology — Posted on 2023-10-26
830 Predicting Pseudomonas aeruginosa drug resistance using artificial intelligence and clinical MALDI-TOF mass spectra
Nguyen, H.-A.; Peleg, A. Y.; Song, J.; Antony, B.; Webb, G. I.; Wisniewski, J. A.; Blakeway, L. V.; Badoordeen, G. Z.; Theegala, R.; Zisis, H.; Dowe, D. L.; Macesic, N.
10.1101/2023.10.25.563934 — microbiology — Posted on 2023-10-26
831 Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted / founder sensitivity to broadly neutralizing antibodies
Ratnapriya, S.; Pothula, K. R.; Dam, K.-M. A.; Parthasarathy, D.; Benet, H. C.; Parsons, R.; Huang, X.; Sammour, S.; Janowska, K.; Harris, M.; Ahmed, S.; Sacco, S.; Sodroski, J.; Bridges, M.; Hubbell, W.; Acharya, P.; Herschhorn, A.
10.1101/2023.09.13.557082 — microbiology — Posted on 2023-10-26
834 Mixotrophic microalgal mixed cultures for cheese whey valorization
Giulianetti de Almeida, M. P.; Mondini, C.; Bruant, G.; Tremblay, J.; Mockaitis, G.; Weissbrodt, D. G.
10.1101/2023.10.24.563819 — microbiology — Posted on 2023-10-26
836 DEVELOPMENT AND EVALUATION OF COATED RICOTTA CHEESE WITH WHEY PROTEIN AND CLOVE OIL
Aamir, M. A.; Sarwar, E.; Ahmed, A.; Saeed, F.; Ikram, A.; Afzaal, M.; Kiran, F.; Ateeq, H.; Akram, N.; Hussain, S.; Khan, M. R.
10.1101/2023.10.25.563938 — microbiology — Posted on 2023-10-26
841 Engineered yeast cells simulating CD19+ cancers to control CAR T cell activation
Deichmann, M.; Schiesaro, G.; Ramanathan, K.; Zeeberg, K. V. W.; Koefoed, N. M. T.; Ormhoj, M.; Friis, R. U. W.; Gill, R. T.; Hadrup, S. R.; Jensen, E. D.; Jensen, M. K.
10.1101/2023.10.25.563929 — synthetic biology — Posted on 2023-10-26
843 Genomic characterization of a nematode tolerance locus in sugar beet
Sielemann, K.; Pucker, B.; Orsini, E.; Elashry, A.; Schulte, L.; Viehoever, P.; Mueller, A. E.; Schechert, A.; Weisshaar, B.; Holtgraewe, D.
10.1101/2023.06.22.546034 — plant biology — Posted on 2023-10-26
844 NPEPPS is a novel and druggable driver of platinum resistance
Jones, R. T.; Scholtes, M.; Goodspeed, A.; Akbarzadeh, M. M.; Mohapatra, S.; Feldman, L. E.; Vekony, H.; Jean, A.; Tilton, C. B.; Orman, M. V.; Romal, S.; Deiter, C.; Kan, T. W.; Xander, N.; Araki, S.; Joshi, M.; Javaid, M.; Clambey, E. T.; Layer, R.; Laajala, T. D.; Parker, S.; Zuiverloon, T.; Theodorescu, D.; Costello, J. C.
10.1101/2021.03.04.433676 — cancer biology — Posted on 2023-10-26
847 Its a Trap?! Escape from an ancient, ancestral sex chromosome system and implication of Foxl2 as the putative primary sex determining gene in a lizard (Anguimorpha; Shinisauridae)
Pinto, B. J.; Nielsen, S. V.; Sullivan, K. A.; Behere, A.; Keating, S. E.; van Schingen-Khan, M.; Nguyen, T. Q.; Ziegler, T.; Pramuk, J.; Wilson, M. A.; Gamble, T.
10.1101/2023.07.05.547803 — evolutionary biology — Posted on 2023-10-26
849 Multimodal analysis reveals genes driving neuronal maturation in the primate prefrontal cortex
Gao, Y.; Dong, Q.; Arachchilage, K. H.; Risgaard, R.; Sheng, J.; Syed, M.; Schmidt, D. K.; Jin, T.; Liu, S.; Knaack, S. A.; Doherty, D.; Glass, I.; Levine, J. E.; Wang, D.; Chang, Q.; Zhao, X.; Sousa, A. M.
10.1101/2023.06.02.543460 — neuroscience — Posted on 2023-10-26
851 Cell-type-resolved somatic mosaicism reveals clonal dynamics of the human forebrain
Chung, C.; Yang, X.; Hevner, R. F.; Kennedy, K.; Vong, K. I.; Liu, Y.; Patel, A.; Nedunuri, R.; Barton, S. T.; Barrows, C.; Stanley, V.; Mittal, S.; Breuss, M. W.; Schlachetzki, J. C. M.; Gleeson, J. G.
10.1101/2023.10.24.563814 — neuroscience — Posted on 2023-10-26
852 Mapping functional traces of opioid memories in the rat brain
Gomes-Ribeiro, J.; Martins, J.; Sereno, J.; Deslauriers-Gauthier, S.; Summavielle, T.; Coelho, J. E.; Remondes, M.; Castelo-Branco, M.; Lopes, L. V.
10.1101/2023.08.07.552221 — neuroscience — Posted on 2023-10-26
857 C. elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA
Consalvo, C. D.; Aderounmu, A. M.; Donelick, H. M.; Aruscavage, P. J.; Eckert, D. M.; Shen, P. S.; Bass, B. L.
10.1101/2023.09.21.558868 — biochemistry — Posted on 2023-10-26
858 Dual Recognition of Multiple Signals in Bacterial Outer Membrane Proteins Enhance Assembly and Maintain Membrane Integrity
Germany, E. M.; Thewasano, N.; Imai, K.; Maruno, Y.; Bamert, R. S.; Stubenrauch, C. J.; Dunstan, R. A.; Ding, Y.; Nakajima, Y.; Lai, X.; Webb, C. T.; Hidaka, K.; Tan, K. S.; Shen, H.-H.; Lithgow, T.; Shiota, T.
10.1101/2021.10.29.466387 — biochemistry — Posted on 2023-10-26
861 Imputation Efficacy Across Global Human Populations
Cahoon, J. L.; Rui, X.; Tang, E.; Simons, C.; Langie, J.; Chen, M.; Lo, Y.-C.; Chiang, C. W. K.
10.1101/2023.05.22.541241 — genetics — Posted on 2023-10-26
863 Hybridization and its impact on the ontogenetic allometry of skulls in macaques
Ito, T.; Kimura, R.; Wakamori, H.; Tanaka, M.; Tezuka, A.; Nagano, A. J.; Hamada, Y.; kawamoto, Y.
10.1101/2023.04.19.536293 — evolutionary biology — Posted on 2023-10-26
864 Transcriptomic responses of sponge holobionts to in situ, seasonal anoxia and hypoxia
Strehlow, B. W.; Schuster, A.; Francis, W. R.; Eckford-Soper, L.; Kraft, B.; McAllen, R.; Nielsen, R.; Mandrup, S.; Canfield, D. E.
10.1101/2023.02.27.530229 — ecology — Posted on 2023-10-26
865 Mutation in the Bone Morphogenetic Protein signaling pathway sensitize zebrafish and humans to ethanol-induced jaw malformations
Klem, J. R.; Schwantes-An, T.-H.; Abreu, M.; Suttie, M.; Gray, R.; Vo, H.; Conley, G.; Foroud, T. M.; Wetherill, L.; CIFASD, ; Lovely, C. B.
10.1101/2023.06.28.546932 — developmental biology — Posted on 2023-10-26
866 Wound-Induced Syncytia Outpace Mononucleate Neighbors during Drosophila Wound Repair
White, J. S.; Su, J. J.; Ruark, E. M.; Hua, J.; Hutson, M. S.; Page-McCaw, A.
10.1101/2023.06.25.546442 — cell biology — Posted on 2023-10-26
875 Increased deformations are dispensable for cell mechanoresponse in engineered bone analogs mimicking aging bone marrow
Regner, A. M.; DeLeon, M.; Gibbons, K. D.; Howard, S.; Nesbitt, D. Q.; Lujan, T. J.; Fitzpatrick, C. K.; Farach-Carson, M. C.; Wu, D.; Uzer, G.
10.1101/2023.09.24.559187 — bioengineering — Posted on 2023-10-26
877 High-resolution CTCF footprinting reveals impact of chromatin state on cohesin extrusion dynamics
Sept, C. E.; Tak, Y. E.; Cerda-Smith, C. G.; Hutchinson, H. M.; Goel, V.; Blanchette, M.; Bhakta, M. S.; Hansen, A. S.; Joung, J. K.; Johnstone, S.; Eyler, C. E.; Aryee, M. J.
10.1101/2023.10.20.563340 — genomics — Posted on 2023-10-26
878 Genetic contributions of noncognitive skills to academic development
Malanchini, M.; Allegrini, A. G.; Nivard, M. G.; Biroli, P.; Rimfeld, K.; Cheesman, R.; von Stumm, S.; Demange, P. A.; van Bergen, E.; Grotzinger, A. D.; Raffington, L.; de la Fuente, J.; Pingault, J.-B.; Tucker-Drob, E. M.; Harden, K. P.; Plomin, R.
10.1101/2023.04.03.535380 — genetics — Posted on 2023-10-26
879 Coupling of Nuclear Translocation to Cell Size Promotes Robustness to Fluctuations in YAP/TAZ Concentration
Jones, I.; Garcia, M. A.; Vargas, P. P.; Beykou, M.; Dent, L. G.; Choudhary, T.; Roumeliotis, T. I.; Chaudhary, J. S.; Sero, J. E.; Bakal, C.
10.1101/2023.02.06.527281 — cell biology — Posted on 2023-10-26
885 Role of Dopamine Neurons in Familiarity
Fleury, S.; Kolaric, R.; Espera, J. J.; Ha, Q.; Tomaio, J. N.; Gether, U.; Sorensen, A. T.; Mingote, S.
10.1101/2023.10.25.564006 — animal behavior and cognition — Posted on 2023-10-25
887 Convergent evolution of complex adaptive traits enabled human life at high altitudes
Ferraretti, G.; Rill, A.; Abondio, P.; Smith, K.; Ojeda-Granados, C.; De Fanti, S.; Izzi, M.; Sherpa, P. T.; Cocco, P.; Tiriticco, M.; di Marcello, M.; Dezi, A.; Gnecchi-Ruscone, G. A.; Natali, L.; Corcelli, A.; Marinelli, G.; Garagnani, P.; Peluzzi, D.; Luiselli, D.; Pettener, D.; Sarno, S.; Sazzini, M.
10.1101/2023.10.24.563738 — evolutionary biology — Posted on 2023-10-25
888 Offline hippocampal reactivation during dentate spikes supports flexible memory
McHugh, S. B.; Lopes-dos-Santos, V.; Castelli, M.; Gava, G. P.; Thompson, S. E.; Tam, S. K. E.; Hartwich, K.; Dupret, D.
10.1101/2023.10.24.563714 — neuroscience — Posted on 2023-10-25
890 The intracellular domain of the epilepsy-related protein PCDH19 regulates spine density in cortical neurons.
Newbold, S. A.; Fox, I. W. J.; Llinares-Benadero, C.; Fabra-Beser, J.; Stebleva, E.; Gil-Sanz, C.; Martinez-Garay, I.
10.1101/2023.10.25.563961 — neuroscience — Posted on 2023-10-25
893 Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Covalent Warhead
Elshan, N. G. R. D.; Wolff, K. C.; Riva, L.; Woods, A. K.; Grabovyi, G.; Wilson, K.; Rahimi, A.; Pedroarena, J.; Ghorai, S.; Gupta, A. K.; Nazarian, A.; Weiss, F.; Liu, Y.; Mazumdar, W.; Song, L.; Okwor, N.; Malvin, J.; Bakowski, M. A.; Beutler, N.; Kirkpatrick, M. G.; Gebara-Lamb, A.; Huang, E.; Nguyen-Tran, V.; Chi, V.; Li, S.; Rogers, T. F.; McNamara, C. W.; Chen, J. J.; Joseph, S. B.; Schultz, P. G.; Chatterjee, A. K.
10.1101/2023.10.24.563688 — microbiology — Posted on 2023-10-25
894 Cross-platform comparison of highly-sensitive immunoassays for inflammatory markers in a COVID-19 cohort
Abe, K.; Beer, J. C.; Nguyen, T.; Ariyapala, I. S.; Holmes, T. H.; Feng, W.; Zhang, B.; Kuo, D.; Luo, Y.; Ma, X.-J.; Maecker, H. T.
10.1101/2023.10.24.563866 — immunology — Posted on 2023-10-25
897 Simulation-Driven Design of Stabilized SARS-CoV-2 Spike S2 Immunogens
Nuqui, X.; Casalino, L.; Zhou, L.; Shehata, M.; Wang, A.; Tse, A. L.; Ojha, A.; Kearns, F. L.; Rosenfeld, M. A.; Miller, E. H.; Acreman, C. M.; Ahn, S.-H.; Chandran, K.; McLellan, J. S.; Amaro, R. E.
10.1101/2023.10.24.563841 — biophysics — Posted on 2023-10-25
898 Functional Tissue Units in the Human Reference Atlas.
Bidanta, S.; Börner, K.; Herr, B. W.; Nagy, M.; Gustilo, K. S.; Bajema, R.; Maier, L.; Molontay, R.; Weber, G.
10.1101/2023.10.16.562593 — bioinformatics — Posted on 2023-10-25
899 VIPERA: Viral Intra-Patient Evolution Reporting and Analysis
Alvarez-Herrera, M.; Sevilla, J.; Ruiz-Rodriguez, P.; Vergara, A.; Vila, J.; Cano-Jimenez, P.; Gonzalez-Candelas, F.; Comas, I.; Coscolla, M.
10.1101/2023.10.24.561010 — bioinformatics — Posted on 2023-10-25
900 Benchmarking the accuracy of structure-based binding affinity predictors on Spike-ACE2 Deep Mutational Interaction Set
Ozden, B.; Samiloglu, E.; Ozsan, A.; Erguven, M.; Yukruk, C.; Kosaca, M.; Oktayoglu, M.; Mentes, M.; Arslan, N.; Karakulah, G.; Barlas, A. B.; Savas, B.; Karaca, E.
10.1101/2022.04.18.488633 — bioinformatics — Posted on 2023-10-25
902 WITHDRAWN: L-Carnitine on contrast-induced nephropathy in diabetic rats
Oliveira, N. A.; Couto, S. M. F.; Borges, F. T.; Vattimo, M. d. F. F.; da Fonseca, C. D.
10.1101/2023.08.10.552846 — pharmacology and toxicology — Posted on 2023-10-25
903 Resolving haplotype variation and complex genetic architecture in the human immunoglobulin kappa chain locus in individuals of diverse ancestry
Engelbrecht, E.; Rodriguez, O. L.; Shields, K.; Schulze, S.; Tieri, D.; Jana, U.; Yaari, G.; Lees, W.; Smith, M. L.; Watson, C. T.
10.1101/2023.10.23.563321 — immunology — Posted on 2023-10-25
906 Borrowing Transcriptional Kinases to Activate Apoptosis
Sarott, R. C.; Gourisankar, S. P.; Karim, B. A.; Nettles, S.; Yang, H.; Dwyer, B.; Simanauskaite, J. M.; Tse, J.; Abuzaid, H.; Krokhotin, A.; Zhang, T.; Hinshaw, S. M.; Green, M. R.; Crabtree, G. R.; Gray, N.
10.1101/2023.10.23.563687 — cancer biology — Posted on 2023-10-25
908 Protein Language Models Uncover Carbohydrate-Active Enzyme Function in Metagenomic
Thurimella, K.; Mohamed, A. M. T.; Graham, D. B.; Owens, R. M.; La Rosa, S. L.; Plichta, D. R.; Bacallado, S.; Xavier, R. J.
10.1101/2023.10.23.563620 — bioinformatics — Posted on 2023-10-25
909 Acoustomechanically activatable liposomes for ultrasonic drug uncaging
Purohit, M. P.; Sinha Roy, K.; Xiang, Y.; Yu, B. J.; Azadian, M. M.; Muwanga, G.; Hart, A. R.; Taoube, A. K.; Gomez Lopez, D.; Airan, R. D.
10.1101/2023.10.23.563690 — bioengineering — Posted on 2023-10-25
910 Multi-Factor Coral Disease Risk Forecasting for Early Warning and Management
Caldwell, J. M.; Liu, G.; Geiger, E.; Heron, S. F.; Eakin, C. M.; De La Cour, J.; Greene, A.; Raymundo, L.; Dryden, J.; Schlaff, A.; Stella, J. S.; Kindinger, T. L.; Couch, C. S.; Fenner, D.; Hoot, W.; Manzello, D.; Donahue, M. J.
10.1101/2023.10.23.563632 — ecology — Posted on 2023-10-25
916 Lipin-1 restrains macrophage lipid synthesis to promote inflammation resolution.
Bamgbose, T. T.; Schilke, R. M.; Igiehon, O. O.; Nkadi, E. H.; Custis, D.; Bharrhan, S.; Schwarz, B.; Bohrnsen, E.; Bosio, C.; Scott, R. S.; Yurdagul, A.; Finck, B.; Woolard, M.
10.1101/2023.10.23.563587 — immunology — Posted on 2023-10-25
918 Multi-Site Statistical Mapping of Along-Tract Microstructural Abnormalities in Bipolar Disorder with Diffusion MRI Tractometry
Nabulsi, L.; Qamar, B.; McPhilemy, G.; Martyn, F. M.; Roberts, G.; Hallahan, B.; Dannlowski, U.; Kircher, T.; Haarman, B.; Mitchell, P. B.; McDonald, C.; Cannon, D. M.; Andreassen, O. A.; Ching, C. R. K.; Thompson, P. M.
10.1101/2023.08.17.553762 — neuroscience — Posted on 2023-10-25
919 Intrinsic properties of spinal motoneurons degrade ankle torque control in humans
Beauchamp, J. A.; Pearcey, G. E. P.; Khurram, O. U.; Negro, F.; Dewald, J. P. A.; Heckman, C.
10.1101/2023.10.23.563670 — physiology — Posted on 2023-10-25
920 Unlocking the Role of sMyBP-C: A Key Player in Skeletal Muscle Development and Growth
Song, T.; McNamara, J.; Baby, A.; Ma, W.; Landim-Vieira, M.; Natesan, S.; Pinto, J. R.; Lorenz, J. N.; Irving, T.; Sadayappan, S.
10.1101/2023.10.23.563591 — physiology — Posted on 2023-10-25
921 β-aminopropionitrile Induces Distinct Pathologies in the Ascending and Descending Thoracic Aortic Regions of Young Mice
Franklin, M. K.; Sawada, H.; Howatt, D. A.; Amioka, N.; Liang, C.-L.; Zhang, N.; Graf, D. B.; Moorleghen, J. J.; Katsumata, Y.; Lu, H. S.; Daugherty, A.
10.1101/2023.10.22.563474 — pathology — Posted on 2023-10-25
922 New races with wider virulence indicate local evolution of Puccinia striiformis f. sp. tritici in South America
Riella, V.; Rodriguez-Algaba, J.; Garcia, R.; Pereira, F.; Silva, P.; Hovmoller, M.; German, S.
10.1101/2023.10.23.563651 — pathology — Posted on 2023-10-25
924 A Germline Point Mutation in the MYC-FBW7 Phosphodegron Initiates Hematopoietic Malignancies
Freie, B.; Carroll, P. A.; Varnum-Finney, B. J.; Ramani, V.; Bernstein, I.; Eisenman, R. N.
10.1101/2023.10.23.563660 — cancer biology — Posted on 2023-10-25
925 Inference and design of antibody specificity: from experiments to models and back
Fernandez-de-Cossio-Diaz, J.; Uguzzoni, G.; Ricard, K.; Anselmi, F.; Pagnani, A.; Nizak, C.; Rivoire, O.
10.1101/2023.10.23.563570 — biophysics — Posted on 2023-10-25
927 Quantifying fluorescence lifetime responsiveness of environment sensitive probes for membrane fluidity measurements
Ragaller, F.; Sjule, E.; Urem, Y. B.; Schlegel, J.; El, R.; Urbancic, D.; Urbancic, I.; Blom, H.; Sezgin, E.
10.1101/2023.10.23.563572 — biophysics — Posted on 2023-10-25
929 Extracellular modulation of TREK-2 activity with nanobodies provides insights into the mechanism of K2P channel regulation
Rodstrom, K. E. J.; Cloake, A.; Sormann, J.; Baronina, A.; Smith, K. H. M.; Pike, A. C. W.; Ang, J.; Proks, P.; Schewe, M.; Holland-Kaye, I.; Bushell, S. R.; Elliott, J.; Pardon, E.; Baukrowitz, T.; Owens, R. J.; Newstead, S.; Steyaert, J.; Carpenter, E. P.; Tucker, S. J.
10.1101/2023.10.19.562917 — biophysics — Posted on 2023-10-25
934 Hyperbolic graph embedding of MEG brain networks to study brain alterations in individuals with subjective cognitive decline
Baker, C.; Mendez, I. S.; Smith, G.; Marsh, E. B.; Funke, M.; Mosher, J. C.; Maestu, F.; Xu, M.; Pantazis, D.
10.1101/2023.10.23.563643 — bioinformatics — Posted on 2023-10-25
936 Synthetic Biodegradable Void-forming Hydrogels for In Vitro 3D Culture of Functional Human Bone Cell Networks
Zauchner, D.; Muller, M. Z.; Horrer, M.; Bissig, L.; Zhao, F.; Lee, S. S.; Muller, R.; Qin, X.-H.
10.1101/2023.10.23.563580 — bioengineering — Posted on 2023-10-25
937 Comprehensive Assessment of Blood-Brain Barrier Opening and Sterile Inflammatory Response: Unraveling the Therapeutic Window
Martinez, P. J.; Song, J. J.; Garay, F. G.; Song, K.-H.; Mufford, T.; Steiner, J.; DeSisto, J.; Ellens, N.; Serkova, N. J.; Green, A. L.; Borden, M. A.
10.1101/2023.10.23.563613 — bioengineering — Posted on 2023-10-25
938 Effect of homotypic vs. heterotypic interactions on the cellular uptake of extracellular vesicles
Jhaveri, J. R.; Khare, P.; Kamte, Y. S.; Chandwani, M. N.; Pinky, P. P.; Milosevic, J.; Abraham, N.; Zheng, S.-y.; O'Donnell, L.; Manickam, D. S.
10.1101/2023.10.23.563628 — bioengineering — Posted on 2023-10-25
940 Neurogenomic landscape associated with status-dependent cooperative behavior
Bolton, P. E.; Ryder, T. B.; Dakin, R.; Houtz, J. L.; Moore, I. T.; Balakrishnan, C. N.; Horton, B. M.
10.1101/2022.10.05.510848 — evolutionary biology — Posted on 2023-10-25
941 Genetic drift and purifying selection shape within-host influenza A virus populations during natural swine infections
VanInsberghe, D.; McBride, D. S.; DaSilva, J.; Stark, T. J.; Lau, M. S. Y.; Shepard, S. S.; Barnes, J. R.; Bowman, A.; Lowen, A. C.; Koelle, K.
10.1101/2023.10.23.563581 — evolutionary biology — Posted on 2023-10-25
943 A method for sampling parasitized Drosophila suzukii puparia from soil
Capko, C.; Thiessen, J.; Harach, L.; Fraser, J. L.; Franklin, M. T.; Abram, P. K.
10.1101/2023.10.23.563656 — ecology — Posted on 2023-10-25
944 Improving forest ecosystem functions by optimizing tree species spatial arrangement
Beugnon, R.; Albert, G.; Hahn, G.; Haider, S.; Hattenschwiler, S.; Davrinche, A.; Rosenbaum, B.; Gauzens, B.; Eisenhauer, N.
10.1101/2023.10.23.563583 — ecology — Posted on 2023-10-25
945 TGFb induced embryonic cell senescence at the origin of the Cornelia de Lange syndrome
Hachoud, C.; Chaabani, F.; Watrin, E.; Wuelling, M.; Peters, h.; Cormier, V.; Puceat, M.
10.1101/2022.07.26.501526 — developmental biology — Posted on 2023-10-25
947 Sex and species associated differences in Complement-mediated immunity in Humans and Rhesus macaques
Kelkar, N. S.; Goldberg, B. S.; Dufloo, J.; Bruel, T.; Schwartz, O.; Hessell, A. J.; Ackerman, M. E.
10.1101/2023.10.23.563614 — immunology — Posted on 2023-10-25
949 Resolving haplotype variation and complex genetic architecture in the human immunoglobulin kappa chain locus in individuals of diverse ancestry
Engelbrecht, E. E.; Rodriguez, O. L.; Shields, K. T.; Schulze, S.; Tieri, D.; Jana, U.; Yaari, G.; Lees, W.; Smith, M. L.; Watson, C. T.
10.1101/2023.10.23.563321 — immunology — Posted on 2023-10-25
950 Absolute number of three populations of interneurons and all GABAergic synapses in the human hippocampus
Takacs, V.; Papp, P.; Orosz, A.; Bardoczi, Z.; Zsoldos, T.; Watanabe, M.; Magloczky, Z.; Gombas, P.; Freund, T. F.; Nyiri, G.
10.1101/2023.09.26.559559 — neuroscience — Posted on 2023-10-25
951 Brief change in dopamine activity during consolidation impairs long-term memory via sleep disruption
Yan, L.; Wu, L.; Wiggin, T. D.; Su, X.; Yan, W.; Li, H.; Li, L.; Lu, Z.; Meng, Z.; Guo, F.; Griffith, L.; Li, F.; Liu, C.
10.1101/2023.10.23.563499 — neuroscience — Posted on 2023-10-25
953 Platelet proteo-transcriptomic profiling validates mediators of thrombosis and proteostasis in patients with myeloproliferative neoplasms
Kelliher, S.; Gamba, S.; Weiss, L.; Shen, Z.; Marchetti, M.; Schieppati, F.; Scaife, C.; Madden, S.; Bennett, K.; Fortune, A.; Maung, S.; Fay, M.; Ni Ainle, F.; Maguire, P.; Falanga, A.; Kevane, B.; Krishnan, A.
10.1101/2023.10.23.563619 — pathology — Posted on 2023-10-25
954 Beneficial effects of intermittent fasting in NASH and subsequent HCC development are executed by concerted PPAR alpha and PCK1 action in hepatocytes
Gallage, S.; Ali, A.; Barragan Avila, J. E.; Seymen, N.; Ramadori, P.; Joerke, V.; Zizmare, L.; Kosla, J.; Li, X.; Focaccia, E.; Yousuf, S.; Sijmonsma, T.; Rahbari, M.; Kommoss, K. S.; Billeter, A.; Prokosch, S.; Rothermel, U.; Mueller, F.; Hetzer, J.; Heide, D.; Machauer, T.; Malek, N. P.; Longerich, T.; Rose, A. J.; Roth, S.; Schwenck, J.; Trautwein, C.; Karimi, M. M.; Heikenwalder, M.
10.1101/2023.10.23.562885 — cancer biology — Posted on 2023-10-25
960 Substrate profiling of human Transglutaminase 1 using cDNA display and next-generation sequencing
Munaweera, T. I. K.; Damnjanovic, J.; Camagna, M.; Nezu, M.; Jia, B.; Hitomi, K.; Nemoto, N.; Nakano, H.
10.1101/2023.10.22.563423 — bioengineering — Posted on 2023-10-25
961 Regulating the proinflammatory response to implanted composite biomaterials comprising polylactide and hydroxyapatite by targeting immunometabolism
Maduka, C. V.; Makela, A. V.; Ural, E.; Stivers, K. B.; Kuhnert, M. M.; Tundo, A.; Alhaj, M.; Hoque Apu, E.; Ashammakhi, N.; Hankenson, K. D.; Narayan, R.; Elisseeff, J. H.; Contag, C. H.
10.1101/2023.10.21.563447 — bioengineering — Posted on 2023-10-25
962 Pulmonary Ventilation Analysis Using 1H Ultra-Short Echo Time (UTE) Lung MRI: A Reproducibility Study
Tan, F.; Zhu, X.; Chan, M.; Deveshwar, N.; Willmering, M. M.; Lustig, M.; Larson, P. E. Z.
10.1101/2023.10.22.563196 — bioengineering — Posted on 2023-10-25
963 The history of chromosomal instability in genome doubled tumors
Baker, T. M.; Lai, S.; Lesluyes, T.; Yan, H.; Verfaillie, A.; Dentro, S.; Lynch, A. R.; Bowes, A. L.; Pillay, N.; Flanagan, A. M.; Swanton, C.; Tarabichi, M.; Van Loo, P.
10.1101/2023.10.22.563273 — genomics — Posted on 2023-10-25
964 Cryptic diversity and signatures of domestication in the Black Soldier Fly (Hermetia illucens)
Generalovic, T. N.; Sandrock, C.; Roberts, B. J.; Meier, J. I.; Hauser, M.; Warren, I. A.; Pipan, M.; Durbin, R.; Jiggins, C. D.
10.1101/2023.10.21.563413 — genomics — Posted on 2023-10-25
968 cSTAR analysis identifies endothelial cell cycle as a key regulator of flow-dependent artery remodeling
Deng, H.; Rukhlenko, O. S.; Joshi, D.; Hu, X.; Junk, P.; Tuliakova, A.; Kholodenko, B. N.; Schwartz, M. A.
10.1101/2023.10.24.563764 — cell biology — Posted on 2023-10-25
969 Rebalancing the motor circuit restores movement in a Caenorhabditis elegans model for TDP-43-toxicity
Koopman, M.; Gungordu, L.; Janssen, L.; Seinstra, R. I.; Richmond, J. E. X.; Okerlund, N.; Wardenaar, R.; Islam, P.; Brown, A. E. X.; Jorgensen, E. M.; Nollen, E. A. A.
10.1101/2023.10.24.563563 — cell biology — Posted on 2023-10-25
970 A novel genetic fluorescent reporter to visualize mitochondrial nucleoids
Deng, J.; Swift, L.; Shahhosseini, F.; Jaiswal, A.; Brideau, C.; Colarusso, P.; Shutt, T. E.
10.1101/2023.10.23.563667 — cell biology — Posted on 2023-10-25
972 BirthSeq, a new method to isolate and analyze dated cells from any tissue in vertebrates
Rueda-Alana, E.; Grillo, M.; Vazquez, E.; Marco Salas, S.; Senovilla-Ganzo, R.; Escobar, L.; Quintas, A.; Benguria, A.; Aransay, A. M.; Dopazo, A.; Encinas, J. M.; Nilsson, M.; Garcia-Moreno, F.
10.1101/2023.10.10.559090 — developmental biology — Posted on 2023-10-25
976 CSTA: A Biomarker Regulating Esophageal Stricture Epithelial Barrier, Potential Medication Target
Yang, F.; HU, Y.; Shi, Z.; Jin, H.; Hu, K.; Ye, G.; Pang, Q.; Hou, R.; Tang, K.; Zhu, Y.
10.1101/2023.10.23.563568 — cell biology — Posted on 2023-10-25
977 Increased tau expression in the APOE4 blood-brain barrier model is associated with reduced anti-tau therapeutic antibody delivery in vitro.
Wasielewska, J. M.; Bajracharya, R.; Johnston, R. L.; Chaves, J. C. S.; Pebay, A.; Oikari, L. E.; Götz, J.; Nisbet, R. M.; White, A. R.
10.1101/2023.10.24.563706 — cell biology — Posted on 2023-10-25
978 A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders
Vincent, A. E.; Chen, C.; Gomes, T. B.; Di Leo, V.; Laalo, T.; Pabis, K.; Capaldi, R.; Mauresch, M.; McDonald, D.; Filby, A.; Fuller, A.; Urban, D. L.; Zeirz, S.; Deschaurer, M.; Turnbull, D. M.; Reeve, A. K.; Lawless, C.
10.1101/2023.10.24.563545 — cell biology — Posted on 2023-10-25
979 Selective Removal of 7KC by a Novel Atherosclerosis Therapeutic Candidate Reverts Foam Cells to a Macrophage-like Phenotype
Bhargava, P.; Dinh, D.; Teramayi, F.; Silberg, A.; Petler, N.; Anderson, A. M.; Clemens, D. M.; O'Connor, M. S.
10.1101/2023.10.23.563623 — cell biology — Posted on 2023-10-25
980 Functional enzymatic assays to predict the potency of extracellular vesicles
Adamo, G.; Picciotto, S.; Gargano, P.; Paterna, A.; Rao, E.; Raccosta, S.; Salamone, M.; Romancino, D. P.; Manno, M.; Bongiovanni, A.
10.1101/2023.10.24.563745 — cell biology — Posted on 2023-10-25
981 A new mode of transcriptional hub assembly by autoimmune regulator Aire
Huoh, Y.-S.; Zhang, Q.; Torner, R.; Baca, S. C.; Arthanari, H.; Hur, S.
10.1101/2023.10.23.563603 — cell biology — Posted on 2023-10-25
982 Diosmetin alleviates liver inflammation by improving liver sinusoidal endothelial cell dysfunction.
Zurawek, D.; Pydyn, N.; Major, P.; Szade, K.; Trzos, K.; Kus, E.; Pospiech, E.; Malczak, P.; Radkowiak, D.; Budzynski, A.; Chlopicki, S.; Jura, J.; Kotlinowski, J.
10.1101/2023.10.23.563468 — cell biology — Posted on 2023-10-25
984 Cell-type-resolved somatic mosaicism reveals clonal dynamics of the human forebrain
Chung, C.; Yang, X.; Hevner, R.; Kennedy, K.; Vong, K. L.; Liu, Y.; Patel, A.; Nedunuri, R.; Barton, S. T.; Barrows, C.; Stanley, V.; Mittal, S.; Breuss, M. W.; Schlachetzki, J. C. M.; Gleeson, J. G.
10.1101/2023.10.24.563814 — neuroscience — Posted on 2023-10-25
985 Profound seizure suppression and disease modification by targeting JAK1, a key driver of a pro-epileptogenic gene network.
Hoffman, O. R.; Patterson, A.; Gohar, E.; Coleman, E.; Schoenike, B.; Espinosa-Garcia, C.; Paredes, F.; Dingledine, R.; Maguire, J.; Roopra, A. S.
10.1101/2023.08.07.552299 — neuroscience — Posted on 2023-10-25
988 Lymphatic muscle cells are the innate pacemaker cells regulating mouse lymphatic collecting vessel contractions
Zawieja, S. D.; Pea, G. A.; Broyhill, S. E.; Bromert, K. H.; Norton, C. E.; Kim, H. J.; Li, M.; Castorena-Gonzalez, J. A.; Drumm, B. T.; Davis, M. J.
10.1101/2023.08.24.554619 — physiology — Posted on 2023-10-25
991 The consequence of ATP synthase dimer angle on mitochondrial morphology studied by cryo-electron tomography
Buzzard, E.; McLaren, M.; Bragoszewski, P.; Brancaccio, A.; Ford, H.; Daum, B.; Kuwabara, P.; Collinson, I.; Gold, V.
10.1101/2023.02.02.526626 — biochemistry — Posted on 2023-10-25
994 Multilayer network associations between the exposome and childhood brain development
Simpson-Kent, I. L.; Gatavins, M. M.; Tooley, U. A.; Boroshok, A. L.; McDermott, C. L.; Park, A. T.; Reyes, L. D.; Bathelt, J.; Tisdall, D.; Mackey, A. P.
10.1101/2023.10.23.563611 — neuroscience — Posted on 2023-10-25
997 An ancient subcortical circuit decides when to orient to threat in humans
Trier, H.; Khalighinejad, N.; Hamilton, S.; Harbison, C.; Priestley, L.; Laubach, M.; Scholl, J.; Rushworth, M. F.
10.1101/2023.10.24.563636 — neuroscience — Posted on 2023-10-25
999 Prediction of antigen-responding VHH antibodies by tracking evolution of antibody along time course of immunization
Matsuda, T.; Akazawa-Ogawa, Y.; Komaba, L.-K.; Kiyose, N.; Miyazaki, N.; Mizuguchi, Y.; Fukuta, T.; Ito, Y.; Hagihara, Y.
10.1101/2021.06.29.449501 — immunology — Posted on 2023-10-24
1002 Light-driven synchronization of optogenetic clocks
Cannarsa, M. C.; Liguori, F.; Pellicciotta, N.; Frangipane, G.; Di Leonardo, R.
10.1101/2023.10.24.563722 — synthetic biology — Posted on 2023-10-24
1008 A public resource of single cell transcriptomes and multiscale networks from persons with and without Alzheimer's disease
Wang, Q.; Antone, J.; Alsop, E.; Reiman, R.; Funk, C.; Bendl, J.; Dudley, J. T.; Liang, W. S.; Karr, T. L.; Roussos, P.; Bennett, D. A.; De Jager, P. L.; Serrano, G. E.; Beach, T. G.; Van Keuren-Jensen, K.; Mastroeni, D.; Reiman, E. M.; Readhead, B. P.
10.1101/2023.10.20.563319 — genomics — Posted on 2023-10-24
1009 Pleiotropic contribution of rbfox1 to psychiatric and neurodevelopmental phenotypes in a zebrafish model
Anton-Galindo, E.; Adel, M.; Garcia-Gonzalez, J.; Leggieri, A.; Lopez-Blanch, L.; Irimia, M.; Norton, W. H.; Brennan, C. H.; Fernandez-Castillo, N.; Cormand, B.
10.1101/2023.02.23.529711 — genetics — Posted on 2023-10-24
1010 Piezo1 mechanosensing regulates integrin-dependent chemotactic migration in human T cells
Liu, C. S. C.; Mandal, T.; Biswas, P.; Hoque, M. A.; Bandopadhyay, P.; Sinha, B. P.; Sarif, J.; D'Rozario, R.; Sinha, D. K.; Sinha, B.; Ganguly, D.
10.1101/2022.08.16.504114 — immunology — Posted on 2023-10-24
1011 A mouse model of oral contraceptive exposure: depression, motivation, and the stress response
Schuh, K. M.; Ahmed, J.; Kwak, E.; Xu, C. X.; Davis, T. T.; Aronoff, C. B.; Tronson, N. C.
10.1101/2023.01.27.525969 — neuroscience — Posted on 2023-10-24
1013 Experience Shapes Chandelier Cell Function and Structure in the Visual Cortex
Seignette, K.; Jamann, N.; Papale, P.; Terra, H.; Porneso, R. P. O.; de Kraker, L.; van der Togt, C.; van der Aa, M.; Neering, P.; Ruimschotel, E.; Roelfsema, P. R.; Montijn, J. S.; Self, M. W.; Kole, M. H. P.; Levelt, C. N.
10.1101/2023.04.21.537780 — neuroscience — Posted on 2023-10-24
1015 Striatin plays a major role in angiotensin II-induced cardiomyocyte and cardiac hypertrophy in mice in vivo.
Cull, J. J.; Cooper, S. T.; Alharbi, H. O.; Chothani, S.; Rackham, O. J.; Meijles, D. N.; Dash, P. R.; Kerkela, R.; Ruparelia, N.; Sugden, P. H.; Clerk, A.
10.1101/2023.10.21.563397 — physiology — Posted on 2023-10-24
1018 OMICmAge: An integrative multi-omics approach to quantify biological age with electronic medical records
Chen, Q.; Dwaraka, V. B.; Carreras-Gallo, N.; Mendez, K.; Chen, Y.; Kachroo, P.; Prince, N.; Went, H.; Mendez, T.; Lin, A.; Turner, L.; Moqri, M.; Chu, S. H.; Kelly, R. S.; Weiss, S. T.; Rattray, N. J.; Gladyshev, V. N.; Karlson, E.; Wheelock, C.; Mathe, E. A.; Dahlin, A.; McGeachie, M. J.; Smith, R.; Lasky-Su, J. A.
10.1101/2023.10.16.562114 — bioinformatics — Posted on 2023-10-24
1019 Proximity proteomics reveals UCH-L1 as an NLRP3 interactor that modulates IL-1β production in human macrophages and microglia
Liang, Z.; Damianou, A.; Vendrell, I.; Jenkins, E.; Lassen, F. H.; Washer, S. J.; Liu, G.; Yi, G.; Lou, H.; Cao, F.; Zheng, X.; Fernandes, R.; Dong, T.; Tate, E. W.; Daniel, E. D.; Kessler, B. M.
10.1101/2023.10.09.561576 — biochemistry — Posted on 2023-10-24
1020 CTCF/cohesin organize the ground state of chromatin-nuclear speckle association
Yu, R.; Roseman, S.; Siegenfeld, A. P.; Nguyen, S. C.; Joyce, E. F.; Liau, B.; Krantz, I. D.; Alexander, K.; Berger, S. L.
10.1101/2023.07.22.550178 — genetics — Posted on 2023-10-24
1021 Predatory fireflies and their toxic firefly prey have evolved distinct toxin resistancestrategies.
Yang, L.; Borne, F.; Betz, A.; Aardema, M. L.; Zhen, Y.; Peng, J.; Wu, M.; Visconti, R.; Roland, B. P.; Talsma, A. D.; Palladino, M.; Petschenka, G.; Andolfatto, P.
10.1101/2023.03.08.531760 — evolutionary biology — Posted on 2023-10-24
1022 A paradigm for regulation at the effector interface with RNA-binding proteins
Shah, K.; He, S.; Turner, D. J.; Corbo, J.; Rebbani, K.; Bateman, J.; Cheloufi, S.; Igreja, C.; Valkov, E.; Murn, J.
10.1101/2023.09.20.558714 — molecular biology — Posted on 2023-10-24
1023 Theoretical Considerations and Empirical Predictions of the Pharmaco- and Population Dynamics of Heteroresistance
Levin, B. R. R.; Berryhill, B. A.; Gil-Gil, T.; Manuel, J. A.; Smith, A. P.; Choby, J. E.; Andersson, D. I.; Weiss, D. S.; Baquero, F.
10.1101/2023.09.21.558832 — microbiology — Posted on 2023-10-24
1024 Early immunomodulatory program triggered by pro-tolerogenic Bifidobacterium pseudolongum drives cardiac transplant outcomes
Gavzy, S. J.; Kensiski, A.; Saxena, V.; Lakhan, R.; Hittle, L.; Wu, L.; Iyyathurai, J.; Dhakal, H.; Lee, Z. L.; Li, L.; Lee, Y.; Zhang, T.; Lwin, H. W.; Shirkey, M. W.; Paluskievicz, C.; Piao, W.; Mongodin, E. F.; Ma, B.; Bromberg, J. S.
10.1101/2022.10.13.511915 — immunology — Posted on 2023-10-24
1025 Mental maps without vision: Neural signatures of cognitive maps based on haptic input in the hippocampal formation
Ottink, L.; van den Berg, L.; Peters, I.; van der Geest, T.; Haak, K.; Doeller, C.; van Wezel, R.
10.1101/2023.10.20.563338 — neuroscience — Posted on 2023-10-24
1029 Pathology of natural infection with highly pathogenic avian influenza virus (H5N1) clade 2.3.4.4b in wild terrestrial mammals in the United States in 2022
Elsmo, E. J.; Wunschmann, A.; Beckmen, K. B.; Broughton-Neiswanger, L. B.; Buckles, E. L.; Ellis, J.; Fitzgerald, S. D.; Gerlach, R.; Hawkins, S.; Ip, H.; Lankton, J.; Lemley, E. M.; Lenoch, J.; Killian, M. L.; Lantz, K.; Long, L.; Maes, R.; Mainenti, M.; Melotti, J.; Moriarty, M. E.; Nakagun, S.; Ruden, R. M.; Shearn-Bochsler, V.; Thompson, D.; Torchetti, M. K.; Van Wettere, A. J.; Wise, A. G.; Lim, A.
10.1101/2023.03.10.532068 — pathology — Posted on 2023-10-24
1030 Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy
Guo, M.; Wu, Y.; Su, Y.; Qian, S.; Krueger, E.; Christensen, R.; Kroeschell, G.; Bui, J.; Chaw, M.; Zhang, L.; Liu, J.; Hou, X.; Han, X.; Ma, X.; Zhovmer, A.; Combs, C.; Moyle, M.; Yemini, E.; Liu, H.; Liu, Z.; La Riviere, P.; Colon-Ramos, D.; Shroff, H.
10.1101/2023.10.15.562439 — bioengineering — Posted on 2023-10-24
1031 Methionine oxidation of Carbohydrate-Active enZymes during white-rot wood decay
Molinelli, L.; Drula, E.; GAILLARD, J.-C.; Navarro, D.; Armengaud, J.; Berrin, J.-G.; Tron, T.; Tarrago, L.
10.1101/2023.10.24.563746 — microbiology — Posted on 2023-10-24
1033 Structure and regulation of GSDMD pores at the plasma membrane of pyroptotic cells
Kappelhoff, S.; Holtmannspoetter, M.; Schaefer, S. L.; Margheritis, E. G.; Veit, H.; Danial, J. S. H.; Strauss, S.; Franzkoch, R.; Psathaki, O. E.; Jungmann, R.; Kurre, R.; Hummer, G.; Piehler, J.; Cosentino, K.
10.1101/2023.10.24.563742 — biophysics — Posted on 2023-10-24
1034 Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens
Ober, V.; Githure, G. B.; Volpato Santos, Y.; Becker, S.; Moya, G.; Basquin, J.; Schwede, F.; Lorentzen, E.; Boshart, M.
10.1101/2023.10.24.563761 — biochemistry — Posted on 2023-10-24
1037 Lysogeny destabilizes computationally simulated microbiomes
Gilman, R. T.; Muldoon, M. R.; Megremis, S.; Robertson, D. L.; Chanishvili, N.; Papadopoulos, N. G.
10.1101/2023.10.23.563560 — ecology — Posted on 2023-10-24
1040 P116 from Mycoplasma is a self-sufficient lipid uptake and delivery machinery
Manger, S.; Arghittu, S. M.; Sprankel, L.; Meier-Credo, J.; Wieland, K.; Schwalm, M. P.; Bublak, D.; Knapp, S.; Langer, J.; Covino, R.; Frangakis, A. S.
10.1101/2023.10.24.563710 — molecular biology — Posted on 2023-10-24
1041 Metataxonomic analysis of halophilic archaea community in two geothermal springs sources in southern Tunisian Sahara
Najjari, A.; Elmnasri, K.; Cherif, H.; Guesmi, A.; Mahjoubi, M.; Linares-Pasten, J. A.; Cherif, A.; Ouzari, H.-I.
10.1101/2023.10.24.563781 — microbiology — Posted on 2023-10-24
1045 Early viral infection of cyanobacteria drives bacterial chemotaxis in the oceans
Henshaw, R. J.; Moon, J.; Stehnach, M. R.; Bowen, B. P.; Kosina, S. M.; Northen, T. R.; Guasto, J. S.; Floge, S. A.
10.1101/2023.10.24.563588 — biophysics — Posted on 2023-10-24
1046 Cyclic peptide inhibitors stabilize Gq/11 heterotrimers
Muehle, J.; Rodrigues, M. J.; Alenfelder, J.; Juergenliemke, L.; Guixa-Gonzalez, R.; Bacchin, A.; Andres, F.; Hennig, M.; Schihada, H.; Cruesemann, M.; Koenig, G.; Kostenis, E.; Schertler, G.; Deupi, X.
10.1101/2023.10.24.563737 — biochemistry — Posted on 2023-10-24
1047 Structure of the yeast ceramide synthase
Schäfer, J.-H.; Clausmeyer, L.; Körner, C.; Esch, B. M.; Wolf, V. N.; Walter, S.; Januliene, D.; Moeller, A.; Fröhlich, F.
10.1101/2023.10.24.563787 — biochemistry — Posted on 2023-10-24
1053 No evidence for highly pathogenic avian influenza virus H5N1 (clade 2.3.4.4b) in the Antarctic region during the austral summer 2022/23
Lisovski, S.; Gunther, A.; Dewar, M.; Anley, D.; Arce, R.; Ballard, G.; Belliure, J.; Boulinier, T.; Bennison, A.; Cary, C.; Catry, P.; Clessin, A.; Connan, M.; Cox, A.; Christina, J.; Elrod, M.; Ferreiro, I.; Fowler, Z.; Gamble, A.; Hurtado, J.; Jongsomjit, D.; Lejeune, M.; Lescroel, A.; Li, A.; Morandini, V.; Moratorio, G.; Militao, T.; Moreno, P.; Perbolianachis, P.; Pennycook, J.; Schmidt, A. E.; Smyth, L.; Soutullo, A.; Tornos, J.; Varsani, A.; Herzschuh, U.; Beer, M.; Wille, M.
10.1101/2023.10.24.563692 — microbiology — Posted on 2023-10-24
1055 Investigating how Salmonella colonise alfalfa using a whole genome screen.
Holden, E. R.; Al-Khanaq, H.; Vimont, N. M.; Webber, M. A.; Trampari, E.
10.1101/2023.10.24.563821 — microbiology — Posted on 2023-10-24
1062 DeepGWAS: Enhance GWAS Signals for Neuropsychiatric Disorders via Deep Neural Network
Wen, J.; Li, G.; Chen, j.; Sun, Q.; Liu, W.; Guan, W.; Lai, B.; Zhou, H.; Szatkiewicz, J. P.; Sullivan, P. F.; Li, Y.
10.1101/2022.12.20.521277 — genetics — Posted on 2023-10-24
1065 Age-related spatial ecology of Audouin's gull during the non-breeding season
Ponti, R.; Morera-Pujol, V.; Sallent, A.; Gonzalez-Solis, J.; Ramos, R.
10.1101/2023.10.23.563411 — ecology — Posted on 2023-10-24
1066 A novel class of ultra-stable endospore appendages decorated with collagen-like tip fibrillae
Remaut, H.; Sleutel, M.; Zegeye, E. D.; Llarena, A.-K.; Pradhan, B.; Fislage, M.; O'Sullivan, K.; Aspholm, M. E.
10.1101/2023.10.23.563578 — microbiology — Posted on 2023-10-24
1068 Neural signatures of stress susceptibility and resilience in the amygdala-hippocampal network
Xia, F.; Fascianelli, V.; Vishwakarma, N.; Ghinger, F. G.; Fusi, S.; Kheirbek, M.
10.1101/2023.10.23.563652 — neuroscience — Posted on 2023-10-24
1069 Ticks without borders: Microbial communities of immature Neotropical tick species parasitizing migratory landbirds along northern Gulf of Mexico
Karim, S.; Zenzal, T. J.; Beati, L.; Sen, R.; Adegoke, A.; Kumar, D.; Downs, L.; Keko, M.; Nussbaum, A.; Becker, D.; Moore, F.
10.1101/2023.10.22.563347 — zoology — Posted on 2023-10-24
1071 Nonspecific membrane bilayer perturbations by ivermectin underlie SARS-CoV-2 in vitro activity
Eastman, R. T.; Rusinova, R.; Herold, K. F.; Huang, X.-P.; Dranchak, P.; Voss, T. C.; Rana, S.; Shrimp, J. H.; White, A. D.; Hemmings, H. C.; Roth, B. L.; Inglese, J.; Andersen, O. S.; Dahlin, J. L.
10.1101/2023.10.23.563088 — pharmacology and toxicology — Posted on 2023-10-24
1072 Missense mutations in Myc Box I influence MYC cellular localization, mRNA partitioning and turnover to promote leukemogenesis
Arthur, N.; Christensen, K. A.; Mannino, K.; Ruzinova, M.; Kumar, A.; Gruszczynska, A.; Day, R. B.; Erdmann-Gilmore, P.; Mi, Y.; Sprung, R.; York, C. R.; Spencer, D. H.; Townsend, R.; Sykes, S. M.; Ferraro, F.
10.1101/2023.10.22.563493 — cancer biology — Posted on 2023-10-24
1073 Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia
Boncompagni, G.; Tatangelo, V.; Lopresti, L.; Ulivieri, C.; Capitani, N.; Tangredi, C.; Finetti, F.; Marotta, G.; Frezzato, F.; Visentin, A.; Ciofini, S.; Gozzetti, A.; Bocchia, M.; Calzada-Fraile, D.; Martin Cofreces, N. B.; Trentin, L.; Patrussi, L.; Baldari, C. T.
10.1101/2023.10.23.563260 — cancer biology — Posted on 2023-10-24
1078 Bioactive coatings on 3D printed scaffolds for bone regeneration: Translation from in vitro to in vivo models and the impact of material properties and growth factor concentration.
Marshall, K. M.; Wojciechowski, J. P.; Jayawarna, V.; Hasan, A.; Echalier, C.; Ovrebo, O.; Yang, T.; Kanczler, J. M.; Mata, A.; Salmeron-Sanchez, M.; Stevens, M. M.; Oreffo, R. O. C.
10.1101/2023.10.22.560309 — bioengineering — Posted on 2023-10-24
1080 The origin and maintenance of supergenes contributing to ecological adaptation in Atlantic herring
Jamsandekar, M.; Ferreira, M. S.; Pettersson, M. E.; Farrell, E.; Davis, B. W.; Andersson, L.
10.1101/2023.10.23.562618 — evolutionary biology — Posted on 2023-10-24
1081 Germline novelty through recurrent copy-number, protein, and regulatory evolution of the synaptonemal complex
Wei, K. H.; Chang, C.-H.; Chatla, K.; Krishnapura, A.; Appiah, S. P.; Zhang, J.; Unckless, R. L.; Blumenstiel, J.; Bachtrog, D.
10.1101/2023.10.20.563324 — evolutionary biology — Posted on 2023-10-24
1083 Fertility is compromised after oocyte-specific deletion of Katanin A-subunit, Katna1, but not Katnal1
Yuen, W. S.; Zhang, Q.-H.; Dunstan, M.; Adhikari, D.; Dunleavy, J. E.; O'Connor, A.; O'Bryan, M.; Carroll, J.
10.1101/2023.10.22.563510 — developmental biology — Posted on 2023-10-24
1084 Heterogeneous dual-metal control of Salmonella infection
Roche, B.; Cunrath, O.; Bleck, C.; Claudi, B.; Antelo Varela, M.; Li, J.; Bumann, D.
10.1101/2023.10.23.562652 — cell biology — Posted on 2023-10-24
1085 Vaccination by single dose sporozoite injection of blood stage attenuated malaria parasites
Sattler, J. M.; Keiber, L.; Abdelrahim, A.; Zheng, X.; Jaecklin, M.; Zechel, L.; Moreau, C. A.; Fischer, M. M.; Janse, C. J.; Hoffmann, A.; Hentzschel, F.; Frischknecht, F.
10.1101/2023.10.24.563045 — cell biology — Posted on 2023-10-24
1086 Bacterial diversity and composition on the rinds of specific melon cultivars and hybrids from across different growing regions in the United States
Goforth, M.; Obergh, V.; Park, R.; Porchas, M.; Crosby, K. M.; Jifon, J. L.; Ravishankar, S.; Brierley, P.; Leskovar, D. L.; Turini, T. A.; Schultheis, J.; Coolong, T.; Miller, R.; Koiwa, H.; Patil, B. S.; Cooper, M. A.; Huynh, S.; Parker, C. T.; Guan, W.; Cooper, K.
10.1101/2023.10.23.563553 — microbiology — Posted on 2023-10-24
1088 Microfluidic antibody profiling after repeated SARS-CoV-2 vaccination links antibody affinity and concentration to impaired immunity and variant escape in patients on anti-CD-20 therapy
Priddey, A.; Chen-Xu, M. X. H.; Cooper, D. J.; MacMillan, S.; Meisl, G.; Xu, C. K.; Hosmillo, M.; Goodfellow, I. G.; Kollyfas, R.; Doffinger, R.; Bradley, J. R.; Mohorianu, I. I.; Jones, R.; Knowles, T. P. J.; Smith, R.; Kosmoliaptsis, V.
10.1101/2023.10.22.563481 — immunology — Posted on 2023-10-24
1089 Monocytes reprogrammed by 4-PBA potently contribute to the resolution of inflammation and atherosclerosis
Geng, S.; Lu, R.; Zhang, Y.; Wu, Y.; Xie, L.; Caldwell, B. A.; Pradhan, K.; Yi, Z.; Hou, J.; Xu, F.; Chen, X.; Li, L.
10.1101/2023.10.19.563200 — immunology — Posted on 2023-10-24
1090 Heterotypic responses against nsp12/nsp13 from prior SARS-CoV-2 infection associates with lower subsequent endemic coronavirus incidence
Bean, D. J.; Monroe, J.; Liang, Y. M.; Borberg, E.; Senussi, Y.; Swank, Z.; Chalise, S.; Walt, D.; Weinberg, J.; Sagar, M.
10.1101/2023.10.23.563621 — immunology — Posted on 2023-10-24
1092 Super-Resolution Imaging of Fast Morphological Dynamics of Neurons in Behaving Animals
Zhang, Y.; Bai, L.; Wang, X.; Zhao, Y.; Zhang, T.; Ye, L.; Du, X.; Zhang, Z.; Du, J.; Wang, K.
10.1101/2023.10.23.563526 — neuroscience — Posted on 2023-10-24
1093 Reduction of a-synuclein aggregates by PIKfyve inhibition via TFEB-mediated lysosomal biogenesis in a Parkinson disease model
Lucas-Del-Pozo, S.; Uras, G.; Fierli, F.; Lentini, V.; Koletsi, S.; Chau, K.-Y.; Hughes, D.; Schapira, A. H.
10.1101/2023.10.23.563557 — neuroscience — Posted on 2023-10-24
1094 SARS-CoV-2 induces acute neurological signs while Calcitonin Gene-Related Peptide (CGRP) signaling blockade reduces interleukin 6 (IL-6) release and weight loss in mouse models
Rahman, S. M.; Buchholz, D. W.; Imbiakha, B.; Jaeger, M. C.; Leach, J.; Osborn, R. M.; Birmingham, A. O.; Dewhurst, S.; Aguilar, H. C.; Luebke, A. E.
10.1101/2023.10.23.563669 — neuroscience — Posted on 2023-10-24
1096 Feasibility of intranasal delivery of thin-film freeze-dried monoclonal antibodies
Yu, Y.-S.; Xu, H.; AboulFotouh, K.; Williams, G.; Suman, J.; Sahakijpijarn, S.; Cano, C.; Warnken, Z.; Wu, K. C.- W.; Williams, R. O.; Cui, Z.
10.1101/2023.10.23.563139 — pharmacology and toxicology — Posted on 2023-10-24
1100 Detection of a historic reservoir of bedaquiline / clofazimine resistance associated variants in Mycobacterium tuberculosis
Nimmo, C.; Torres Ortiz, A.; Pang, J.; Acman, M.; Tan, C. C.; Millard, J.; Padayatchi, N.; Grant, A.; O'Donnell, M. R.; Pym, A.; Brynildsrud, O. B.; Eldholm, V.; Grandjean, L.; Didelot, X.; Balloux, F.; van Dorp, L.
10.1101/2020.10.06.328799 — genomics — Posted on 2023-10-24
1101 Genomic epidemiology and antifungal-resistant characterization of Candida auris, Colombia, 2016-2021
Misas, E.; Escandon, P.; Gade, L.; Caceres, D. H.; Hurst, S.; Le, N.; Min, B.; Lyman, M.; Duarte, C.; Chow, N. A.
10.1101/2023.10.20.563341 — genomics — Posted on 2023-10-24
1102 A 50-gene high-risk profile predictive of COVID-19 and Idiopathic Pulmonary Fibrosis mortality originates from a molecular imbalance in monocyte and T-cell subsets that reverses in survivors with post-COVID-19 Interstitial Lung Disease
Tourki, B.; Jia, M.; Karampitsakos, T.; Vera, I. M.; Arsenault, A.; Marlin, K.; Perrot, C. Y.; Allen, D.; Farsaei, F.; Rutenberg, D.; Bandyopadhyay, D.; Restrepo, R.; Qureshi, M. R.; Patel, K.; Tzouvelekis, A.; Kapetanaki, M.; Juan-Guardela, B.; Kim, K.; Benos, P. V.; Herazo-Maya, J.
10.1101/2023.10.22.563156 — genomics — Posted on 2023-10-24
1105 Recurrent gene flow events shaped the diversification of the clownfish skunk complex
Marcionetti, A.; Bertrand, J. A. M.; Cortesi, F.; Donati, G. F. A.; Heim, S.; Huyghe, F.; Kochzius, M.; Pellissier, L.; Salamin, N.
10.1101/2023.10.24.562491 — evolutionary biology — Posted on 2023-10-24
1108 lmeEEG: Mass linear mixed-effects modeling of EEG data with crossed random effects
Visalli, A.; Montefinese, M.; Viviani, G.; Finos, L.; Vallesi, A.; Ambrosini, E.
10.1101/2023.01.18.524560 — neuroscience — Posted on 2023-10-24
1110 Human O-linked Glycosylation Site Prediction Using Pretrained Protein Language Model
Pakhrin, S. C.; Chauhan, N.; Khan, S.; Upadhyaya, J.; Keller, C.; Neuman, L. N.; Beck, M. R.; Blanco, E.
10.1101/2023.10.23.563673 — bioinformatics — Posted on 2023-10-24
1115 Combinatorial CRISPR screens and lectin microarrays identify novel glycosylation regulators
Tsui, C. K.; Twells, N.; Doan, E.; Brooks, J.; Kulepa, A.; Webster, B.; Mahal, L. K.; Dillin, A.
10.1101/2023.10.23.563662 — cell biology — Posted on 2023-10-24
1116 M1 Macrophage-Related Genes Model for NSCLC Immunotherapy Response Prediction
Wu, S.; Sheng, Q.; Liu, P.; Jiao, Z.; Lv, J.; Qiao, R.; Xie, D.; Wang, Z.; Ge, J.; Li, P.; Wei, T.; Lei, J.; Fan, J.; Wang, L.
10.1101/2023.10.21.563445 — immunology — Posted on 2023-10-24
1117 High capacity of Brazilian Aedes aegypti populations to transmit a locally circulating lineage of Chikungunya virus
Freitas, A.; Rezende, F.; Mendonca, S.; Baldon, L.; Silva, E.; Ferreira, F.; Almeida, J.; Amadou, S.; Marcal, B.; Grangeiro, S.; Rocha, M.; Fritsch, H.; Giovanetti, M.; Alcantara, L.; Moreira, L.; Ferreira, A. G.
10.1101/2023.10.23.563517 — immunology — Posted on 2023-10-24
1118 Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding
Jian, F.; Feng, L.; Yang, S.; Yu, Y.; Wang, L.; Song, W.; Yisimayi, A.; Chen, X.; Xu, Y.; Wang, P.; Yu, L.; Wang, J.; Liu, L.; Niu, X.; Wang, J.; Xiao, T.; An, R.; Wang, Y.; Gu, Q.; Shao, F.; Jin, R.; Shen, Z.; Wang, Y.; Wang, X.; Cao, Y. R.
10.1101/2023.08.30.555211 — immunology — Posted on 2023-10-24
1119 Interfacial morphodynamics of proliferating microbial communities
Martinez-Calvo, A.; Trenado-Yuste, C.; Lee, H.; Gore, J.; Wingreen, N. S.; Datta, S. S.
10.1101/2023.10.23.563665 — biophysics — Posted on 2023-10-24
1121 Design of intrinsically disordered protein variants with diverse structural properties
Pesce, F.; Bremer, A.; Tesei, G.; Hopkins, J. B.; Grace, C. R.; Mittag, T.; Lindorff-Larsen, K.
10.1101/2023.10.22.563461 — biophysics — Posted on 2023-10-24
1123 Data-driven regularisation lowers the size barrier of cryo-EM structure determination
Kimanius, D.; Jamali, K.; Wilkinson, M. E.; Lövestam, S.; Velazhahan, V.; Nakane, T.; Scheres, S. H.
10.1101/2023.10.23.563586 — biophysics — Posted on 2023-10-24
1124 ATP-release pannexin channels are gated by lysophospholipids
Henze, E.; Ehrlich, J. J.; Burkhardt, R. N.; Fox, B. W.; Michalski, K.; Kramer, L.; Lenfest, M.; Boesch, J. M.; Schroeder, F. C.; Kawate, T.
10.1101/2023.10.23.563601 — biophysics — Posted on 2023-10-24
1128 A Pipeline for a Primate Projectome: mapping every individual myelinated axon across the whole brain
Wildenberg, G. A.; Boergens, K. M.; Nikitin, V.; Deriy, A.; De Carlo, F.; De Andrade, V.; Xiao, X.; Kasthuri, N.
10.1101/2023.10.23.563679 — neuroscience — Posted on 2023-10-24
1130 Synaptic plasticity in the medial preoptic area of male mice encodes social experiences with female and regulates behavior toward young
Ito, K.; Sato, K.; Tsuneoka, Y.; Maejima, T.; Okuno, H.; Hamasaki, Y.; Murakawa, S.; Yoshihara, C.; Shindo, S.; Uki, H.; Herlitze, S.; Seki, M.; Suzuki, Y.; Sakurai, T.; Kuroda, K. O.; Minami, M.; AMANO, T.
10.1101/2023.10.23.560098 — zoology — Posted on 2023-10-24
1133 ZNF91 is an endogenous repressor of the molecular phenotype associated with X-linked dystonia-parkinsonism (XDP)
Rosenkrantz, J. L.; Raghib, S.; Brandorff, J. E.; Kapadia, A.; Vaine, C. A.; Bragg, D. C.; Farmiloe, G.; Jacobs, F. M. J.
10.1101/2023.10.20.563263 — neuroscience — Posted on 2023-10-23
1134 Proteomic Stratification of Prognosis and Treatment Options for Small Cell Lung Cancer
Huo, Z.; Duan, Y.; Zhan, D.; Xu, X.; Zheng, N.; Cai, J.; Sun, R.; Wang, J.; Cheng, F.; Gao, Z.; Xu, C.; Liu, W.; Dong, Y.; Ma, S.; Zhang, Q.; Zheng, Y.; Lou, L.; Kuang, D.; Chu, Q.; Qin, J.; Wang, G.; Wang, Y.
10.1101/2023.10.22.563494 — cancer biology — Posted on 2023-10-23
1135 The systematic assessment of completeness of public metadata accompanying omics studies
Huang, Y.-N.; Rajesh, A.; Ayyala, R.; Guo, R.; Nakashidze, I.; Wong, M. Y.; Hu, J.; Yu, D.; Peng, Q.; Scheg, G.; Kapur, S.; Patel, K. K.; Ramesh, T.; Wang, K.; Yadav, A.; Liu, F.; Jaiswal, P. V.; Mehta, J. H.; Boldirev, G.; Abedalthagafi, M. S.; Mangul, S.
10.1101/2021.11.22.469640 — bioinformatics — Posted on 2023-10-23
1137 From disturbances to nonlinear fitness and back.
Tuljapurkar, S. D.; Jaggi, H.; Gascoigne, S. J. L.; Zuo, W.; Kajin, M.; Salguero-Gomez, R.
10.1101/2023.10.20.563360 — ecology — Posted on 2023-10-23
1139 Assessing perceptual chromatic equiluminance using a reflexive pupillary response
Ye, L.; Mahony, B. W.; Wang, X.; Daye, P.; Wang, W.; Cavanagh, P.; Pouget, P.; Andolina, I. M.
10.1101/2023.10.19.563116 — neuroscience — Posted on 2023-10-23
1142 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability
Takahashi, M.; Chong, H. B.; Zhang, S.; Lazarov, M.; Harry, S.; Maynard, M.; White, R.; Hilbert, B.; Gohar, M.; Ge, M.; Zhang, J.; Durr, B. R.; Kryukov, G.; Tsou, C.-C.; Brooijmans, N.; Alghali, A.; Rubio, K.; Vilanueva, A.; Harrison, D.; Koglin, A.-S.; Ojeda, S.; Karakyriakou, B.; Healy, A.; Assaad, J.; Makram, F.; Rachimin, I.; Khandelwal, N.; Tien, P.-C.; Popoola, G.; Chen, N.; Vordermark, K.; Richter, M.; Patel, H.; Yang, T.-y.; Griesshaber, H.; Hosp, T.; van den Ouweland, S.; Hara, T.; Bussema, L.; Shi, L.; Rasmussen, M.; Domingues, A. C.; Lawless, A.; Fang, J.; Yoda, S.; Nguyen, L. P.; R
10.1101/2023.10.20.563287 — systems biology — Posted on 2023-10-23
1148 Evaluation of the neutralising antibody response in human and hamster sera against SARS-CoV-2 variants up to and including BA.2.86 using an authentic virus neutralisation assay
Coombes, N. S.; Bewley, K. R.; Le Duff, Y.; Alami-Rahmouni, N.; Ryan, K. A.; Kempster, S.; Ferguson, D.; Davies, E. R.; Weldon, T. M.; Cross, E. S.; Smith, L.; Norris, C.; Rogers-Broadway, K. R.; Lewandowski, K.; Treagus, S.; Pullan, S. T.; Hallis, B.; Charlton, S.; Hall, Y.; Funnell, S. G. P.
10.1101/2023.10.21.563398 — cell biology — Posted on 2023-10-23
1149 Viral envelope proteins fused to multiple distinct fluorescent reporters to probe receptor binding
Tomris, I.; van der Woude, R.; de Paiva Droes Rocha, R.; Torrents de la Pena, A.; Ward, A. B.; de Vries, R. P.
10.1101/2023.10.23.563555 — molecular biology — Posted on 2023-10-23
1150 Comparison of phage and plasmid populations present in the gut microbiota of Parkinson's disease patients
Lecomte, A.; Duru, I. C.; Laine, P.; Shishido, T. K.; Suppula, J.; Paulin, L.; Scheperjans, F.; Pereira, P. A. B.; Auvinen, P.
10.1101/2023.10.23.563061 — microbiology — Posted on 2023-10-23
1155 Hypothalamic control of noradrenergic neurons stabilizes sleep
Broglia, G.; Corsi, G.; Prouvot Bouvier, P.-H.; Tafti, M.; Bandarabadi, M.
10.1101/2023.10.22.563502 — neuroscience — Posted on 2023-10-23
1157 The biological role of local and global fMRI BOLD signal variability in human brain organization
Baracchini, G.; Zhou, Y.; Castanheira, J. d. S.; Hansen, J. Y.; Rieck, J. R.; Turner, G. R.; Grady, C. L.; Misic, B.; Nomi, J.; Uddin, L. Q.; Spreng, R. N.
10.1101/2023.10.22.563476 — neuroscience — Posted on 2023-10-23
1160 A Straightforward Approach for Living Biomembrane Printing onto Nanoparticle
Mizuta, R.; Kanao, E.; Ukyo, K.; Sawada, S.-i.; Ishihama, Y.; Sasaki, Y.; Akiyoshi, K.
10.1101/2023.10.22.563496 — synthetic biology — Posted on 2023-10-23
1164 nf-core/taxprofiler: highly parallelised and flexible pipeline for metagenomic taxonomic classification and profiling
Stamouli, S.; Beber, M. E.; Normark, T.; Christensen, T. A.; Andersson-Li, L.; Borry, M.; Jamy, M.; nf-core community, ; Fellows Yates, J. A.
10.1101/2023.10.20.563221 — genomics — Posted on 2023-10-23
1165 Comprehensive single cell aging atlas of mammary tissues reveals shared epigenomic and transcriptomic signatures of aging and cancer
Angarola, B. L.; Sharma, S.; Katiyar, N.; Kang, H. G.; Nehar-Belaid, D.; Park, S.; Gott, R.; Eryilmaz, G. N.; LaBarge, M. A.; Palucka, K.; Chuang, J. H.; Korstanje, R.; Ucar, D.; Anczukow, O.
10.1101/2023.10.20.563147 — genomics — Posted on 2023-10-23
1169 Y chromosome damage underlies testicular abnormalities in ATR-X syndrome
Carlos, N. L.; Le, T. N. U.; Garvie, A.; Wong, L. H.; Bagheri-Fam, S.; Harley, V. R.
10.1101/2023.10.21.562414 — developmental biology — Posted on 2023-10-23
1170 The Ribosome Assembly Factor Reh1 is Released from the Polypeptide Exit Tunnel in the Pioneer Round of Translation
Musalgaonkar, S.; Yelland, J.; Chitale, R.; Rao, S.; Ozadam, H.; Cenik, C.; Taylor, D.; Johnson, A. W.
10.1101/2023.10.23.563604 — molecular biology — Posted on 2023-10-23
1171 ENDOTHELIAL GENE REGULATORY ELEMENTS ASSOCIATED WITH CARDIOPHARYNGEAL LINEAGE DIFFERENTIATION
Aurigemma, I.; Lanzetta, O.; Cirino, A.; Allegretti, S.; Lania, G.; Ferrentino, R.; Krishnan, V. P.; Angelini, C.; Illingworth, E.; Baldini, A.
10.1101/2023.10.23.563477 — molecular biology — Posted on 2023-10-23
1172 Geranylgeranyl Isoprenoids and Hepatic Rap1a Regulate Basal and Statin-Induced Expression of PCSK9
Wang, Y.; Tinsley, B.; Spolitu, S.; Zadroga, J. A.; Agarwal, H.; Sarecha, A. K.; Ozcan, L.
10.1101/2023.10.23.563509 — molecular biology — Posted on 2023-10-23
1175 High pathogenicity avian influenza A (H5N1) clade 2.3.4.4b virus infection in a captive Tibetan black bear (Ursus thibetanus): investigations based on paraffin-embedded tissues, France, 2022
Bessiere, P.; Gaide, N.; Croville, G.; Crispo, M.; Fusade-Boyer, M.; Abou Monsef, Y.; Dirat, M.; Beltrame, M.; Dendauw, P.; Lemberger, K.; Guerin, J.-L.; Le Loc'h, G.
10.1101/2023.10.19.563114 — microbiology — Posted on 2023-10-23
1179 Interaction Between the Prefrontal and Visual Cortices Supports Subjective Fear
Taschereau-Dumouchel, V.; Cote, M.; Valevicius, D.; Manuel, S.; Cushing, C.; Cortese, A.; Kawato, M.; Lau, H.
10.1101/2023.10.23.562918 — neuroscience — Posted on 2023-10-23
1187 Increased intrinsic membrane excitability is associated with hypertrophic olivary degeneration in spinocerebellar ataxia type 1
Morrison, L. M.; Huang, H.; Handler, H. P.; Fu, M.; Bushart, D. D.; Pappas, S. S.; Orr, H. T.; Shakkottai, V. G.
10.1101/2023.10.23.563657 — neuroscience — Posted on 2023-10-23
1188 Parietal stimulation reverses age-related decline in exploration, learning, and decision-making
Hwang, E. J.; Korde, S.; Han, Y.; Sambangi, J.; Lian, B.; Owusu-Ofori, A.; Diasamidze, M.; Wong, L. M.; Pickering, N.; Begin, S.
10.1101/2023.10.21.563408 — neuroscience — Posted on 2023-10-23
1189 A Novel Semi-automated Proofreading and Mesh Error Detection Pipeline for Neuron Extension
Joyce, J.; Chalavadi, R.; Chan, J.; Tanna, S.; Xenes, D.; Kitchell, L.; Kuo, N.; Rose, V.; Bishop, C.; Rivlin, P.; Villafane-Delgado, M.; Wester, B.
10.1101/2023.10.20.563359 — neuroscience — Posted on 2023-10-23
1190 Changes in reward-induced neural activity upon Cafeteria Diet consumption
Heijkoop, R.; Lalanza, J. F.; Solanas, M.; Alvarez-Monell, A.; Subias-Gusils, A.; Escorihuela, R. M.; Snoeren, E. M.
10.1101/2023.10.20.563269 — neuroscience — Posted on 2023-10-23
1191 Open-source instrumented object to study dexterous object manipulation
Cordova Bulens, D.; du Bois de Dunilac, S.; Delhaye, B.; Lefevre, P.; Redmond, S. J.
10.1101/2023.10.20.563288 — neuroscience — Posted on 2023-10-23
1196 Quantitative imaging of three-dimensional fiber orientation in the human brain via two illumination angles using polarization-sensitive optical coherence tomography
Liu, C.; Ammon, W.; Jones, R.; Nolan, J. C.; Gong, D.; Maffei, C.; Edlow, B. L.; Augustinack, J. C.; Magnain, C.; Yendiki, A. L.; Villiger, M.; Fischl, B.; Wang, H.
10.1101/2023.10.20.563298 — neuroscience — Posted on 2023-10-23
1198 Coordinated changes in a cortical circuit sculpt effects of novelty on neural dynamics
Ito, S.; Piet, A.; Bennett, C.; Durand, S.; Belski, H.; Garrett, M.; Olsen, S. R.; Arkhipov, A.
10.1101/2023.10.21.563440 — neuroscience — Posted on 2023-10-23
1201 Assessing nanobody interaction with SARS-CoV-2 Nsp9
Esposito, G.; Hunashal, Y.; Percipalle, M.; Fogolari, F.; Venit, T.; Leonchiks, A.; Gunsalus, K. C.; Piano, F.; Percipalle, P.
10.1101/2023.10.20.563308 — biophysics — Posted on 2023-10-23
1205 Photoacoustic Imaging for Non-Invasive Assessment of Physiological Biomarkers of Intestinal Injury in Experimental Necrotizing Enterocolitis
Weis, J. A.; Rauh, J. L.; Ellison, M. A.; Cruz-Diaz, N.; Yamaleyeva, L. M.; Welch, C. D.; Zeller, K. A.; Weis, V. G.
10.1101/2023.10.20.563296 — bioengineering — Posted on 2023-10-23
1206 Cell Chirality of Micropatterned Endometrial Microvascular Endothelial Cells
Zambuto, S. G.; Jain, I.; Theriault, H. S.; Underhill, G. H.; Harley, B.
10.1101/2023.10.20.563368 — bioengineering — Posted on 2023-10-23
1209 In vivo affinity maturation of murine B cells reprogrammed to express human antibodies
Yin, Y.; Guo, Y.; Jiang, Y.; Quinlan, B.; Peng, H.; Crynen, G.; He, W.; Zhang, L.; Ou, T.; Bailey, C. C.; Farzan, M.
10.1101/2023.10.20.563154 — bioengineering — Posted on 2023-10-23
1212 Micrococcin cysteine-to-thiazole conversion through transient interactions between a scaffolding protein and two modification enzymes
Calvopina-Chavez, D. G.; Bursey, D. M.; Tseng, Y.-J.; Patil, L. M.; Bewley, K. D.; Bennallack, P. R.; McPhie, J. M.; Wagstaff, K. B.; Daley, A.; Miller, S. M.; Moody, J. D.; Price, J. C.; Griffitts, J. S.
10.1101/2023.10.23.563616 — biochemistry — Posted on 2023-10-23
1218 A Deep Dive into Single-Cell RNA Sequencing Foundation Models
Boiarsky, R.; Singh, N. M.; Buendia, A.; Getz, G.; Sontag, D.
10.1101/2023.10.19.563100 — genomics — Posted on 2023-10-23
1219 Conifers concentrate large numbers of NLR immune receptor genes on one chromosome
Woudstra, Y.; Tumas, H.; Van Ghelder, C.; Hung, T. H.; Ilska, J. J.; Girardi, S.; A'Hara, S.; McLean, P.; Lee, S. J.; Cottrell, J.; Bohlmann, J.; Bousquet, J.; Birol, I.; Woolliams, J. A.; MacKay, J. J.
10.1101/2023.10.20.563305 — genomics — Posted on 2023-10-23
1220 High-resolution CTCF footprinting reveals impact of chromatin state on cohesin extrusion dynamics
Sept, C. E.; Tak, Y. E.; Cerda-Smith, C. G.; Hutchinson, H. M.; Goel, V.; Blanchette, M.; Bhakta, M. S.; Hansen, A. S.; Joung, J. K.; Johnstone, S.; Eyler, C. E.; Aryee, M. J.
10.1101/2023.10.20.563340 — genomics — Posted on 2023-10-23
1222 Socioecological drivers of injuries in female and male rhesus macaques (Macaca mulatta)
Pavez Fox, M. A.; De Moor, D.; Siracusa, E.; Ellis, S.; Kimock, C.; Rivera-Barreto, N.; Negron-Del Valle, J.; Phillips, D.; Ruiz-Lambides, A.; Snyder-Mackler, N.; Higham, J.; Brent, L.
10.1101/2023.10.20.563310 — evolutionary biology — Posted on 2023-10-23
1225 Insect Pollinators: The Time is Now for Identifying Species of Greatest Conservation Need
deMaynadier, P. G.; Schlesinger, M. D.; Hardy, S. P.; McFarland, K. P.; Saucier, L. L.; White, E. L.; Zarrillo, T. A.; Young, B. E.
10.1101/2023.10.20.563282 — ecology — Posted on 2023-10-23
1227 Master transcription factor binding sites are necessary for early replication control element activity
Turner, J. L.; Gilbert, D. M.; Ay, F.; Hinojosa-Gonzalez, L.; Vouzas, A.; Sasaki, T.; Fitch, C. A.; Brown, A. N.; Alexander, K. E.; Soto, M. S.; Chakraborty, A.
10.1101/2023.10.22.563497 — molecular biology — Posted on 2023-10-23
1228 Diurnal control of iron responsive element (IRE)-containing mRNAs through iron regular proteins IRP1 and IRP2 is mediated by feeding rhythms
Nadimpalli, H. P.; Katsioudi, G.; Arpa, E. S.; Chikhaoui, L.; Arpat, A. B.; Liechti, A.; Palais, G.; Tessmer, C.; Hofmann, I.; Galy, B.; Gatfield, D.
10.1101/2023.10.23.563593 — molecular biology — Posted on 2023-10-23
1230 Integrated Computational Biophysics approach for Drug Discovery against Nipah Virus
Palacios, G. R.; Zuta, M. C.; Galarza, J. P. R.; Villarreal, E. G.; Silva, J. P.; Otazu, K.; Aguila, I. N. d.; Wong, H. D.; Amay, F. S.; Dattani, N.; Camps, I.; Patil, R. B.; Moin, A. T.
10.1101/2023.10.23.563595 — microbiology — Posted on 2023-10-23
1231 Soil fungi remain active and invest in storage compounds during drought independent of future climate conditions
Canarini, A.; Fuchslueger, L.; Schnecker, J.; Metze, D.; Nelson, D.; Kahmen, A.; Watzka, M.; Poetsch, E. M.; Schaumberger, A.; Bahn, M.; Richter, A.
10.1101/2023.10.23.563577 — microbiology — Posted on 2023-10-23
1232 Host tracheal and intestinal microbiomes inhibit Coccidioides growth in vitro
Tejeda-Garibay, S.; Zhao, L.; Hum, N. R.; Pimentel, M.; Diep, A. L.; Amiri, B.; Sindi, S.; Weilhammer, D.; Loots, G. G.; Hoyer, K. K.
10.1101/2023.10.23.563655 — microbiology — Posted on 2023-10-23
1237 Prdm1 Positively Regulates Liver Type 1 ILCs Cancer Immune Surveillance and Preserves Functional Heterogeneity
He, J.; Gao, L.; Wang, P.; Chan, W. K.; Zheng, Y.; Zhang, Y.; Wang, J.; Chen, H.; Yang, Z.; Wang, Y.
10.1101/2023.10.20.563222 — immunology — Posted on 2023-10-23
1240 Generation of circulating autoreactive pre-plasma cells fueled by naive B cells in celiac disease
Lindeman, I.; Hoydahl, L. S.; Christophersen, A.; Risnes, L. F.; Jahnsen, J.; Lundin, K. E. A.; Sollid, L. M.; Iversen, R.
10.1101/2023.10.20.563227 — immunology — Posted on 2023-10-23
1242 Endogenous opioids gate the locus coeruleus pain generator
Norris, M. R.; Kuo, C.-C.; Kim, J. R.; Dunn, S. S.; Borges, G.; Thang, L. V.; McCall, J. G.
10.1101/2023.10.20.562785 — neuroscience — Posted on 2023-10-23
1243 ZNF91 is an endogenous repressor of the molecular phenotype associated with X-linked dystonia-parkinsonism (XDP)
Rosenkrantz, J. L.; Raghib, S.; Brandorff, J. E.; Kapadia, A.; Vaine, C. A.; Bragg, D. C.; Farmiloe, G.; Jacobs, F. L.
10.1101/2023.10.20.563263 — neuroscience — Posted on 2023-10-23
1244 A Brain Model of Altered Self-Appraisal in Social Anxiety Disorder
Jamieson, A. J.; Harrison, B. J.; Delahoy, R.; Schmaal, L.; Felmingham, K.; Phillips, L.; Davey, C.
10.1101/2023.04.26.537105 — neuroscience — Posted on 2023-10-23
1245 Kynurenic acid promotes activity-dependent synaptic pruning in schizophrenia
Orhan, F.; Malwade, S.; Khanlarkhani, N.; Gkoga, A.; Jungholm, O.; Koskuvi, M.; Lehtonen, S.; Schwieler, L.; Jardemark, K.; Tiihonen, J.; Koistinaho, J.; Erhardt, S.; Engberg, G.; S, S.; Sellgren-Majkowitz, C.
10.1101/2023.10.19.563090 — neuroscience — Posted on 2023-10-23
1246 Cellular rules underlying psychedelic control of prefrontal pyramidal neurons
Ekins, T. G.; Brooks, I.; Kailasa, S.; Rybicki-Kler, C.; Jedrasiak-Cape, I.; Donoho, E.; Mashour, G. A.; Rech, J.; Ahmed, O. J.
10.1101/2023.10.20.563334 — neuroscience — Posted on 2023-10-23
1248 Attentional Engagement and Disengagement: Quantifying Attentional Shifts Utilizing the Steady State Visual Evoked Potentials
Eidelman-Rothman, M.; Reuveni, O.; Keil, A.; Kritzman, L.; Freche, D.; Okon-Singer, H.; Levit-Binnun, N.
10.1101/2023.10.21.563393 — neuroscience — Posted on 2023-10-23
1249 Using an ODE model to separate Rest and Task signals in fMRI
Kashyap, A.; Geenjaar, E. P. T.; Bey, P.; Dhindsa, J.; Glomb, K.; Plis, S.; Keilholz, S.; Ritter, P.
10.1101/2023.10.23.563564 — neuroscience — Posted on 2023-10-23
1250 Distinct eLPB ChAT projections for methamphetamine anxiety and relapse
Chen, W.; Guo, H.; Zhou, N.; Xu, X.; Mai, Y.; He, T.; Wen, J.; Ge, F.; Qin, S.; Liu, C.; Wu, W.; Kim, H. Y.; Fan, Y.; Guan, X.
10.1101/2023.10.23.563030 — neuroscience — Posted on 2023-10-23
1251 Structural characterization of SLYM - a 4th cranial meningeal membrane
Pl, V.; Bitsika, S.; Giannetto, M.; Ladron-de-Guevara, A.; Gahn Martinez, D.; Mori, Y.; Nedergaard, M.; Mollgard, K.
10.1101/2023.10.20.563351 — neuroscience — Posted on 2023-10-23
1254 Refined movement analysis in the Staircase test reveals differential motor deficits in mouse models of stroke
Skrobot, M.; De Sa, R.; Walter, J.; Vogt, A.; Paulat, R.; Lips, J.; Mosch, L.; Mueller, S.; Dominiak, S.; Sachdev, R.; Boehm-Sturm, P.; Dirnagl, U.; Endres, M.; Harms, C.; Wenger, N.
10.1101/2023.10.23.563529 — neuroscience — Posted on 2023-10-23
1255 Patterns of subregional cerebellar atrophy across epilepsy syndromes: An ENIGMA-Epilepsy study
Kerestes, R.; Perry, A.; Vivash, L.; O'Brien, T.; Alvim, M. K. M.; Arienzo, D.; Aventurato, I. K.; Ballerini, A.; Baltazar, G. F.; Bargallo, N.; Bender, B.; Brioschi, R.; Bürkle, E.; Caligiuri, M. E.; Cendes, F.; de Tisi, J.; Duncan, J. S.; Engel, J. P.; Foley, S.; Fortunato, F.; Gambardella, A.; Giacomini, T.; Guerrini, R.; Hall, G.; Hamandi, K.; Ives-Deliperi, V.; Joao, R. B.; Keller, S. S.; Kleiser, B.; Labate, A.; Lenge, M.; Marotta, C.; Martin, P.; Mascalchi, M.; Meletti, S.; Owens-Walton, C.; Parodi, C. b.; Pascual-Diaz, S.; Powell, D.; Rao, J.; Rebsamen, M.; Reiter, J.; Riva, A.; Rüeb
10.1101/2023.10.21.562994 — neuroscience — Posted on 2023-10-23
1256 C-section and systemic inflammation synergize to disrupt the neonatal gut microbiota and brain development in a model of prematurity
Morin, C.; Faure, F.; Guenoun, D.; Sautet, I.; Diao, S.; Faivre, V.; Hua, J.; Schwendimann, L.; Mokhtari, A.; Martin, R.; Chadi, S.; Demene, C.; Delahaye Duriez, A.; Diaz Heijtz, R.; Fleiss, B.; Matrot, B.; Auger, S.; Tanter, M.; Van Steenwinckel, J.; Gressens, P.; BOKOBZA, C. E.
10.1101/2023.10.20.563256 — neuroscience — Posted on 2023-10-23
1257 Fine-tuning TrailMap: The utility of transfer learning to improve the performance of deep learning in axon segmentation of light-sheet microscopy images
Oostrom, M.; Muniak, M.; Eichler West, R. M.; Akers, S.; Pande, P.; Obiri, M.; Wang, W.; Bowyer, K.; Wu, Z.; Bramer, L. M.; Mao, T.; Webb-Robertson, B.-J. M.
10.1101/2023.10.23.563546 — neuroscience — Posted on 2023-10-23
1262 Single nuclei transcriptomics in human and non-human primate striatum implicates neuronal DNA damage and proinflammatory signaling in opioid use disorder
Phan, B. N.; Ray, M. H.; Xue, X.; Fu, C.; Fenster, R. J.; Kohut, S. J.; Bergman, J.; Haber, S. N.; Mccullough, K. M.; Kuppe-Fish, M. K.; Glausier, J. R.; Su, Q.; Tipton, A. E.; Lewis, D. A.; Freyberg, Z.; Tseng, G. C.; Ressler, K. J.; Russek, S. J.; Alekseyev, Y.; Seney, M. L.; Pfenning, A. R.; Logan, R. W.
10.1101/2023.05.17.541145 — neuroscience — Posted on 2023-10-23
1268 Endothelial Cell Serum and Glucocorticoid Regulated Kinase 1 (SGK1) Mediates Vascular Stiffening
Zhang, L.; Sun, Z.; Yang, Y.; Mack, A.; Rogers, M.; Aroor, A. R.; Jia, G.; Sowers, J. R.; Hill, M. A.
10.1101/2023.10.19.563167 — physiology — Posted on 2023-10-23
1269 Fast myosin binding protein C knockout in skeletal muscle alters length-dependent activation and myofilament structure.
Hessel, A. L.; Kuehn, M.; Han, S.-W.; Ma, W.; Irving, T. C.; Momb, B. A.; Song, T.; Sadayappan, S.; Linke, W. A.; Palmer, B. M.
10.1101/2023.10.19.563160 — physiology — Posted on 2023-10-23
1270 Neurophysiological Features of STN LFP underlying Sleep Fragmentation in Parkinson's Disease
Zhang, G.; Yu, H.; Chen, Y.; Gong, C.; Hao, H.; Guo, Y.; Xu, S.; Zhang, Y.; Yuan, X.; Yin, G.; Zhang, J.; Tan, H.; Li, L.
10.1101/2023.10.19.563075 — physiology — Posted on 2023-10-23
1275 Machine learning links T cell function and spatial localization to neoadjuvant immunotherapy and clinical outcome in pancreatic cancer
Blise, K. E.; Sivagnanam, S.; Betts, C. B.; Betre, K.; Kirchberger, N.; Tate, B.; Furth, E. E.; Dias Costa, A.; Nowak, J. A.; Wolpin, B. M.; Vonderheide, R. H.; Goecks, J.; Coussens, L. M.; Byrne, K.
10.1101/2023.10.20.563335 — cancer biology — Posted on 2023-10-23
1277 Novel diagnosis and progression microRNA signatures in melanoma
Gomez-Martinez, H.; Lopez-Cerdan, A.; Poley-Gil, M.; Hernando, E.; Garcia-Garcia, F.
10.1101/2023.10.20.563284 — cancer biology — Posted on 2023-10-23
1279 Molecular mechanism of α-synuclein aggregation on lipid membranes revealed.
Dear, A. J.; Teng, X.; Ball, S. R.; Lewin, J.; Horne, R. I.; Clow, D.; Harper, N.; Yahya, K.; Michaels, T. C.; Linse, S.; Knowles, T. P.; Yang, X.; Brewerton, S. C.; Thomson, J.; Habchi, J.; Meisl, G.
10.1101/2023.10.20.563279 — biophysics — Posted on 2023-10-23
1285 An artificial intelligence method for phenotyping of OCT scans using unsupervised and self-supervised deep learning
Kazeminasab, S.; Sekimitsu, S.; Fazli, M.; Eslami, M.; Shi, M.; Tian, Y.; Luo, Y.; Wang, M.; Elze, T.; Zebardast, N.
10.1101/2023.10.20.563205 — bioinformatics — Posted on 2023-10-23
1287 Simulation of adaptive immune receptors and repertoires with complex immune information to guide the development and benchmarking of AIRR machine learning
Chernigovskaya, M.; Pavlovic, M.; Kanduri, C.; Gielis, S.; Robert, P. A.; Scheffer, L.; Slabodkin, A.; Haff, I. H.; Meysman, P.; Yaari, G.; Sandve, G. K.; Greiff, V.
10.1101/2023.10.20.562936 — bioinformatics — Posted on 2023-10-23
1289 Matrix architecture and mechanics regulate myofibril organization, costamere assembly, and contractility of engineered myocardial microtissues
DePalma, S. J.; Jillberto, J.; Stis, A. E.; Huang, D. D.; Lo, J.; Davidson, C. D.; Chowdhury, A.; Jewett, M. E.; Kobeissi, H.; Chen, C. S.; Lejeune, E.; Helms, A. S.; Nordsletten, D. A.; Baker, B.
10.1101/2023.10.20.563346 — bioengineering — Posted on 2023-10-23
1291 Multiomics characterization of cell type repertoires for urine liquid biopsies
Vorperian, S. K.; DeFelice, B. C.; Buonomo, J. A.; Chinchinian, H. J.; Gray, I. J.; Yan, J.; Mach, K. E.; La, V.; Lee, T. J.; Liao, J. C.; Lafayette, R.; Loeb, G. B.; Bertozzi, C. R.; Quake, S. R.
10.1101/2023.10.20.563226 — genomics — Posted on 2023-10-23
1292 A novel amphibian sex determination candidate gene, evolved by structural variation in the regulatory region between X and Y
Kuhl, H.; Tan, W.-H.; Klopp, C.; Kleiner, W.; Koyun, B.; Ciorpac, M.; Feron, R.; Knytl, M.; Kloas, W.; Schartl, M.; Winkler, C. W.; Stoeck, M.
10.1101/2023.10.20.563234 — genomics — Posted on 2023-10-23
1294 A public resource of single cell transcriptomes and multiscale networks from persons with and without Alzheimer's disease
Wang, Q.; Antone, J.; Alsop, E.; Reiman, R.; Funk, C.; Bendl, J.; Dudley, J. T.; Liang, W. S.; Karr, T. L.; Roussos, P.; Bennett, D. A.; De Jager, P. L.; Serrano, G.; Beach, T.; Van Keuren-Jensen, K.; Mastroeni, D.; Reiman, E. M.; Readhead, B. P.
10.1101/2023.10.20.563319 — genomics — Posted on 2023-10-23
1295 Mammalian circadian clock proteins form dynamic interacting microbodies distinct from phase separation
Xie, P.; Xie, X.; Ye, C.; Dean, K.; Laothamatas, I.; Taufique, S. K. T.; Takahashi, J.; Yamazaki, S.; Xu, Y.; Liu, Y.
10.1101/2023.10.19.563153 — genetics — Posted on 2023-10-23
1296 Discovery of a locus associated with susceptibility to esca dieback in grapevine
Arnold, G.; Prado, E.; Dumas, V.; Butterlin, G.; Duchene, E.; Avia, K.; Merdinoglu, D.
10.1101/2023.10.20.563213 — genetics — Posted on 2023-10-23
1299 Impacts of mate quality on female intrasexual aggression in two sister Malurus fairywren species
Jones, J. A.; Feeney, W. E.; Jones, D. N.; Nason, D.; Ketaloya, S.; Karubian, J.
10.1101/2023.10.19.563140 — ecology — Posted on 2023-10-23
1302 The neural basis of swap errors in working memory
Alleman, M.; Panichello, M.; Buschman, T. J.; Johnston, W. J.
10.1101/2023.10.09.561584 — neuroscience — Posted on 2023-10-23
1304 Assessing perceptual chromatic equiluminance using a reflexive pupillary response
Ye, L.; Mahony, B. W.; Wang, X.; Daye, P.; Wang, W.; Cavanagh, P.; Pouget, P.; Andolina, I. M.
10.1101/2023.10.19.563116 — neuroscience — Posted on 2023-10-23
1310 A High-Fat and Fructose Diet in Dogs Mirrors Insulin Resistance and β-cell Dysfunction Characteristic of Impaired Glucose Tolerance in Humans
Gregory, J. M.; Kraft, G.; Man, C. D.; Slaughter, J. C.; Scott, M. F.; Hastings, J. R.; Edgerton, D.; Moore, M. C.; Cherrington, A. D.
10.1101/2023.10.19.563103 — physiology — Posted on 2023-10-23
1311 Pharmacological and behavioral effects of tryptamines present in psilocybin-containing mushrooms
Rakoczy, R. J.; Runge, G. N.; Sen, A. K.; Sandoval, O.; Nguyen, Q.; Roberts, B. R.; Sciortino, J. H.; Gibbons, W. J.; Friedberg, L. M.; Jones, J. A.; McMurray, M. S.
10.1101/2023.10.19.563138 — pharmacology and toxicology — Posted on 2023-10-23
1313 Multi-omic identification of key transcriptional regulatory programs during endurance exercise training
Smith, G. R.; Zhao, B.; Lindholm, M. E.; Raja, A.; Viggars, M. R.; Pincas, H.; Gay, N. R.; Sun, Y.; Ge, Y.; Nair, V. D.; Sanford, J. A.; Amper, M. A. S.; Vasoya, M.; Smith, K. S.; Montgomery, S. B.; Zaslavsky, E.; Bodine, S. C.; Esser, K. A.; Walsh, M. J.; Snyder, M.; Sealfon, S. C.
10.1101/2023.01.10.523450 — genomics — Posted on 2023-10-23
1314 Mitochondrial haplotype and mito-nuclear matching drive somatic mutation and selection throughout aging
Serrano, I.; Hirose, M. H.; Valentine, C.; Roesner, S.; Schmidt, E.; Pratt, G.; Williams, L.; Salk, J.; Ibrahim, S.; Sudmant, P. H.
10.1101/2023.03.06.531392 — genomics — Posted on 2023-10-23
1317 I feel your pain: Higher empathy is associated with higher posterior default mode network activity
Oliva, V.; Riegner, G.; Dean, J.; Khatib, L.; Allen, A.; Barrows, D.; Chen, C.; Fuentes, R.; Jacobson, A.; Lopez, C.; Mosbey, D.; Reyes, M.; Ross, J.; Uvarova, A.; Liu, T.; Zeidan, F.
10.1101/2023.08.11.553004 — neuroscience — Posted on 2023-10-23
1318 Differentiation between Descending Thoracic Aortic Diseases using Machine Learning and Plasma Proteomic Signatures
Momenzadeh, A.; Kreimer, S.; Guo, D.; Ayres, M.; Berman, D.; Chyu, K.-Y.; Shah, P. K.; Milewicz, D.; Azizzadeh, A.; Meyer, J. G.; Parker, S.
10.1101/2023.04.26.538468 — systems biology — Posted on 2023-10-23
1320 Extrachromosomal Telomeres Derived from Excessive Strand Displacements
Lee, J.; Lee, J.; Sohn, E. J.; Taglialatela, A.; O'Sullivan, R. J.; Ciccia, A.; Min, J.
10.1101/2023.07.31.551186 — biochemistry — Posted on 2023-10-23
1321 Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis
Wise, C.; Yu, H.; Khanshour, A. M.; Ushiki, A.; Otomo, N.; Koike, Y.; Einarsdottir, E.; Fan, Y.; Antunes, L.; Kidane, Y. H.; Cornelia, R.; Sheng, R.; Zhang, Y.; Pei, J.; Grishin, N. V.; Evers, B. M. V.; Cheung, J. P. Y.; Herring, J. A.; Terao, C.; Song, Y.-Q.; Gurnett, C.; Gerdhem, P.; Ikegawa, S.; Rios, J. J.; Ahituv, N.
10.1101/2023.05.26.542293 — genetics — Posted on 2023-10-23
1327 Emergent signal execution modes in biochemical reaction networks calibrated to experimental data
Ortega, O. O.; Ozen, M.; Wilson, B. A.; Pino, J. C.; Irvin, M. W.; Ildefonso, G. V.; Garbett, S. P.; Lopez, C. F.
10.1101/2021.01.26.428266 — systems biology — Posted on 2023-10-23
1328 DeepGWAS: Enhance GWAS Signals for Neuropsychiatric Disorders via Deep Neural Network
Wen, J.; Li, G.; Chen, j.; Sun, Q.; Liu, W.; Guan, W.; Lai, B.; Szatkiewicz, J. P.; He, X.; Sullivan, P. F.; Li, Y.; Zhou, H.
10.1101/2022.12.20.521277 — genetics — Posted on 2023-10-23
1329 Multiple axes of visual system diversity in Ithomiini, an ecologically diverse tribe of mimetic butterflies
Wainwright, J. B.; Schofield, C.; Conway, M.; Phillips, D.; Martin-Silverstone, E.; Brodrick, E. A.; Cicconardi, F.; How, M. J.; Roberts, N. W.; Montgomery, S.
10.1101/2023.07.18.549450 — evolutionary biology — Posted on 2023-10-23
1331 The pelvic organs receive no parasympathetic innervation
Sivori, M.; Dempsey, B.; Chettouh, Z.; Boismoreau, F.; Ayerdi, M.; Eymael, A.; Baulande, S.; Lameiras, S.; Coulpier, F.; Delattre, O.; Rohrer, H.; Mirabeau, O.; Brunet, J.-F.
10.1101/2023.07.11.548500 — neuroscience — Posted on 2023-10-23
1332 Diagnostic and Therapeutic Microbial Circuit with Application to Intestinal Inflammation
Merk, L. N.; Shur, A. S.; Jena, S.; Munoz, J.; Brubaker, D.; Murray, R. M.; Green, L. N.
10.1101/2020.11.10.377085 — synthetic biology — Posted on 2023-10-23
1333 Dermonecrosis caused by spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib
Bartlett, K. E.; Hall, S. R.; Rasmussen, S. A.; Crittenden, E.; Dawson, C. A.; Albulescu, L.-O.; Laprade, W. M.; Harrison, R. A.; Saviola, A. J.; Modahl, C. M.; Jenkins, T. P.; Wilkinson, M. C.; Gutierrez, J. M.; Casewell, N. R.
10.1101/2023.07.20.549878 — pharmacology and toxicology — Posted on 2023-10-23
1337 Polysaccharide breakdown products drive degradation-dispersal cycles of foraging bacteria through changes in metabolism and motility
Stubbusch, A. K. M.; Keegstra, J. M.; Schwartzman, J.; Pontrelli, S.; Clerc, E. E.; Stocker, R.; Magnabosco, C.; Schubert, O. T.; Ackermann, M.; D'Souza, G. G.
10.1101/2023.07.14.548877 — microbiology — Posted on 2023-10-23
1338 A High Fraction of Oral Bacteria in the Feces Indicates Gut Microbiota Depletion with Implications for Human Health
Liao, C.; Rolling, T.; Djukovic, A.; Fei, T.; Mishra, V.; Liu, H.; Lindberg, C.; Dai, L.; Zhai, B.; Peled, J. U.; van den Brink, M. R. M.; Hohl, T. M.; Xavier, J. B.
10.1101/2022.10.24.513595 — microbiology — Posted on 2023-10-23
1339 Ultrasound neuromodulation of an anti-inflammatory pathway at the spleen produces sustained improvement of experimental pulmonary hypertension
Zafeiropoulos, S.; Ahmed, U.; Bekiaridou, A.; Mughrabi, I.; Jayaprakash, N.; Saleknezhad, N.; Chadwick, C.; Daytz, A.; Sato, I.; Atish-Fregoso, Y.; Carroll, K.; Al-Abed, Y.; Fudim, M.; Puleo, C.; Giannakoulas, G.; Nicolls, M. R.; Diamond, B.; Zanos, S.
10.1101/2023.03.28.534567 — neuroscience — Posted on 2023-10-23
1341 Cellular contributions to ictal population signals
Lau, L. A.; Zhao, Z.; Gomperts, S. N.; Staley, K. J.; Lillis, K. P.
10.1101/2022.07.08.499193 — neuroscience — Posted on 2023-10-23
1343 Contributions of hyperactive mutations in Mpro from SARS-CoV-2 to drug resistance
Flynn, J. M.; Zvornicanin, S. N.; Shaqra, A. M.; Kurt Yilmaz, N.; Moquin, S.; Dovala, D.; Schiffer, C. A.; Bolon, D.
10.1101/2023.09.28.560010 — biochemistry — Posted on 2023-10-23
1344 ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin
Goto, N.; Suke, K.; Yonezawa, N.; Nishihara, H.; Sato, Y.; Kujirai, T.; Kurumizaka, H.; Yamagata, K.; Kimura, H.
10.1101/2023.10.20.563387 — cell biology — Posted on 2023-10-23
1349 Integration of shoot-derived polypeptide signals by root TGA transcription factors is essential for survival under fluctuating nitrogen environments
Kobayashi, R.; Ohkubo, Y.; Izumi, M.; Ota, R.; Yamada, K.; Hayashi, Y.; Yamashita, Y.; Noda, S.; Ogawa-Ohnishi, M.; Matsubayashi, Y.
10.1101/2023.10.23.563506 — plant biology — Posted on 2023-10-23
1350 Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice.
Sun, L.; Lv, Z.; Chen, X.; Ye, R.; Tian, S.; Wang, C.; Xie, X.; Yan, L.; Yao, X.; Shao, Y.; Cui, S.; Chen, J.; Liu, J.
10.1101/2023.06.21.545885 — developmental biology — Posted on 2023-10-23
1353 Proteomic Stratification of Prognosis and Treatment Options for Small Cell Lung Cancer
Huo, Z.; Duan, Y.; Zhan, D.; Xu, X.; Zheng, N.; Cai, J.; Sun, R.; Wang, J.; Cheng, F.; Gao, Z.; Xu, C.; Liu, W.; Dong, Y.; Ma, S.; Zhang, Q.; Zheng, Y.; Lou, L.; Kuang, D.; Chu, Q.; Qin, J.; Wang, G.; Wang, Y.
10.1101/2023.10.22.563494 — cancer biology — Posted on 2023-10-23
1356 The dynamics of phage predation on a microcolony
Eriksen, R. S.; Larsen, F.; Svenningsen, S. L.; Sneppen, K.; Mitarai, N.
10.1101/2023.06.13.544539 — microbiology — Posted on 2023-10-23
1358 Supercomputer framework for reverse engineering firing patterns of neuron populations to identify their synaptic inputs
Chardon, M. K.; Wang, Y. C.; Garcia, M.; Besler, E.; Beauchamp, J. A.; D'Mello, M.; Powers, R. K.; Heckman, C. J.
10.1101/2022.12.09.519818 — neuroscience — Posted on 2023-10-23
1360 Inhibiting the GPI Transamidase Subunit GPAA1 Abolishes CD24 Surface Localization and Enhances Macrophage-Mediated Phagocytosis of Ovarian Cancer Cells
Mishra, A. K.; Ye, T.; Banday, S.; Thakare, R. P.; Su, C. C. T.-T.; Pham, N. N. H.; Ali, A.; Kulshreshtha, A.; Chowdhury, S. R.; Simone, T. M.; Hu, K.; Zhu, L. J.; Eisenhaber, B.; Deibler, S. K.; Simin, K.; Thompson, P. R.; Eisenhaber, F.; Malonia, S. K.; Green, M. R.
10.1101/2023.10.21.563315 — cancer biology — Posted on 2023-10-23
1362 Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia
Ung, J.; Tan, S.-F.; Fox, T. E.; Shaw, J. J.; Taori, M.; Horton, B. J.; Golla, U.; Sharma, A.; Szulc, Z. M.; Wang, H.-G.; Chalfant, C. E.; Cabot, M. C.; Claxton, D. F.; Loughran, T. P.; Feith, D. J.
10.1101/2023.10.21.563437 — cancer biology — Posted on 2023-10-23
1363 Disparate pathways for extrachromosomal DNA biogenesis and genomic DNA repair
Rose, J. C.; Wang, I. T.-L.; Daniel, B.; Jones, M. G.; Yost, K. E.; Hung, K. L.; Curtis, E. J.; Mischel, P. S.; Chang, H.
10.1101/2023.10.22.563489 — cancer biology — Posted on 2023-10-23
1364 Preventing NK cell activation in the damaged liver induced by cabozantinib/PD-1 blockade increases survival in hepatocellular carcinoma models
Morita, S.; Kikuchi, H.; Birch, G.; Matsui, A.; Morita, A.; Kobayashi, T.; Ruan, Z.; Huang, P.; Hernandez, A.; Coyne, E. M.; Shin, S. M.; Yarchoan, M.; Kenudson, M. M.; Romee, R.; Ho, W. J.; Duda, D. G.
10.1101/2023.10.20.563378 — cancer biology — Posted on 2023-10-23
1365 Dissecting signaling regulators driving AXL-mediated bypass resistance and associated phenotypes by phosphosite perturbations
Creixell, M.; Taylor, S. D.; Gerritsen, J.; Bae, S. Y.; Jiang, M.; Augustin, T.; Loui, M.; Boixo, C.; Creixell, P.; White, F. M.; Meyer, A. S.
10.1101/2023.10.20.563266 — cancer biology — Posted on 2023-10-23
1369 Modulating Mesenchymal Stromal Cell Microenvironment Alters Exosome RNA Content and Ligament Healing Capacity
Chamberlain, C.; Prabahar, A.; Kink, J.; Mueller, E.; Li, Y.; Yopp, S.; Capitini, C.; William, M.; Hematti, P.; Vanderby, R.; Jiang, P.
10.1101/2023.10.22.563485 — cell biology — Posted on 2023-10-23
1370 Convergence, plasticity, and tissue residence of regulatory T cell response via TCR repertoire prism
Nakonechnaya, T. O.; Moltedo, B.; Putintseva, E. V.; Leyn, S.; Bolotin, D. A.; Britanova, O. V.; Shugay, M.; Chudakov, D. M.
10.1101/2023.06.15.544726 — immunology — Posted on 2023-10-23
1371 An antimicrobial peptide expression platform for targeting pathogenic bacterial species
Rutter, J. W.; Dekker, L.; Clare, C.; McDonald, J. A.; Fedorec, A. J.; Barnes, C. P.
10.1101/2023.10.09.561505 — synthetic biology — Posted on 2023-10-23
1376 Altered projection-specific synaptic remodeling and its modification by oxytocin in an idiopathic autism marmoset model
Noguchi, J.; Watanabe, S.; Oga, T.; Isoda, R.; Nakagaki, K.; Sakai, K.; Sumida, K.; Hoshino, K.; Saito, K.; Miyawaki, I.; Sugano, E.; Tomita, H.; Mizukami, H.; Watakabe, A.; Yamamori, T.; Ichinohe, N.
10.1101/2022.08.24.505057 — neuroscience — Posted on 2023-10-23
1378 The genome of the blind bee louse fly reveals deep convergences with its social host and illuminates Drosophila origins
Bastide, H.; Legout, H.; Dogbo, N.; Ogereau, D.; Prediger, C.; Carcaud, J.; Filee, J.; Garnery, L.; Gilbert, C.; Marion-Poll, F.; Requier, F.; Sandoz, J.-C.; Yassin, A.
10.1101/2022.11.08.515706 — evolutionary biology — Posted on 2023-10-23
1379 PhylteR: efficient identification of outlier sequences in phylogenomic datasets
Comte, A.; Tricou, T.; Tannier, E.; Joseph, J.; Siberchicot, A.; Penel, S.; Allio, R.; Delsuc, F.; Dray, S.; de Vienne, D. M.
10.1101/2023.02.02.526888 — evolutionary biology — Posted on 2023-10-23
1381 Genomic surveillance of antimicrobial-resistant Escherichia coli in fecal sludge and sewage in Uganda
Gomi, R.; Matsumura, Y.; Yamamoto, M.; Tanaka, M.; Komakech, A. J.; Matsuda, T.; Harada, H.
10.1101/2023.05.17.540885 — microbiology — Posted on 2023-10-23
1383 Fingerprinting of brain disease: Connectome identifiability in cognitive decline and Alzheimer s disease
Stampacchia, S.; Asadi, S.; Tomczyk, S.; Ribaldi, F.; Scheffler, M.; Lovblad, K.-O.; Pievani, M.; Fall, A.; Preti, M. G.; Unschuld, P.; Van De Ville, D.; Blanke, O.; Garibotto, V.; Amico, E.; Blanke, O.
10.1101/2022.02.04.479112 — neuroscience — Posted on 2023-10-23
1387 A ubiquitous Microcoleus species causes benthic cyanotoxic blooms worldwide
Junier, P.; Cailleau, G.; Fatton, M.; Udriet, P.; Hashmi, I.; Bregnard, D.; Corona-Ramirez, A.; de Francesco, E.; Kuhn, T.; Mangia, N.; Zhioua, S.; Hunkeler, D.; Bindschedler, S.; Sieber, S.; Gonzalez, D.
10.1101/2023.10.13.562201 — microbiology — Posted on 2023-10-22
1391 Dense Sampling of Taxa and Genomes Untangles the Phylogenetic Backbone of a Non-model Plant Lineage Rife with Deep Hybridization and Allopolyploidy
Xu, C.; Jin, Z.; Wang, H.; Xie, S.; Lin, X.; Hodel, R. G. J.; Zhang, Y.; Ma, D.; Liu, B.; Liu, G.; Jin, S.; Zhao, L.; Wu, J.; Ren, C.; Hong, D.; Liu, B.
10.1101/2023.10.21.563444 — plant biology — Posted on 2023-10-23
1396 Unique Binding and Stabilization Mechanisms Employed By and Engineered Into Nanobodies.
Ketaren, N. E.; Fridy, P. C.; Malashkevich, V.; Sanyal, T.; Brilliantes, M.; Thompson, M. K.; Orens, D. A.; Bonanno, J. B.; Sali, a.; Almo, S. C.; Chait, B. T.; Rout, M. P.
10.1101/2023.10.22.563475 — biochemistry — Posted on 2023-10-22
1399 Developmentally dynamic changes in DNA methylation in the human pancreas
MacCalman, A.; De Franco, E.; Franklin, A.; Flaxman, C. S.; Richardson, S. J.; Murrall, K.; Barts Pancreas Tissue Bank, ; Burrage, J.; Walker, E.; Morgan, N. G.; Hattersley, A.; Dempster, E. L.; Hannon, E.; Jeffries, A. R.; Owens, N. D. L.; Mill, J.
10.1101/2023.10.19.563104 — genomics — Posted on 2023-10-22
1402 Gene flow throughout the evolutionary history of a polymorphic and generalist clownfish
Schmid, S.; Bachmann Salvy, M.; Garcia Jimenez, A.; Bertrand, J. A.; Cortesi, F.; Heim, S.; Huyghe, F.; Litsios, G.; Marcionetti, A.; O'Donnell, J.; Riginos, C.; Tettamanti, V.; Salamin, N.
10.1101/2023.10.19.563036 — evolutionary biology — Posted on 2023-10-22
1404 Cerebral hypoperfusion exacerbates traumatic brain injury in male but not female mice.
Whitehead, B. J.; Corbin, D.; Alexander, M. L.; Bumgarner, J.; Zhang, N.; Karelina, K.; Weil, Z. M.
10.1101/2023.10.19.563077 — neuroscience — Posted on 2023-10-22
1405 Drug-Mediated Control of Receptor Valency Enhances Immune Cell Potency
Finn, P.; Chavez, M.; Chen, X.; Wang, H.; Rane, D. A.; Gurjar, J.; Qi, L. S.
10.1101/2023.01.04.522664 — synthetic biology — Posted on 2023-10-22
1407 Antidiabetic Drugs May Prevent Kidney Damage
Vattimo, M. d. F. F.; Silva, E. O.; Ventura, S.; Lima, C.; Garcia, J.; Maia, A. O.; Gusmao, J. V.; Vieira, G. H. F.; Victoria, C. D. d. P.
10.1101/2023.10.19.563071 — physiology — Posted on 2023-10-22
1410 Parallel on-chip micropipettes enabling quantitative multiplexed characterization of vesicle mechanics and cell aggregates rheology
Landiech, S.; Elias, M.; Lapeze, P.; Ajiyel, H.; Plancke, M.; Laborde, A.; Mesnilgrente, F.; Bourrier, D.; Berti, D.; Montis, C.; Mazenq, L.; Baldo, J.; Roux, C.; Delarue, M.; Joseph, P.
10.1101/2023.10.19.562871 — biophysics — Posted on 2023-10-22
1412 Low-cost camera-based estrous tracking enables transgenesis in Peromyscus leucopus, the primary reservoir for Lyme disease
Buchthal, J.; Chory, E. J.; Hill, Z.; Dennison, C.; Tu, B.; Wierenga, R. P.; Cevrim, C.; Golas, S.; Telford, S. R.; McKinley, K. L.; Jaenisch, R.; Markoulaki, S.; Esvelt, K. M.
10.1101/2023.10.20.563285 — bioengineering — Posted on 2023-10-22
1418 Decision-Making Time Cells in Hippocampal Dorsal CA1
Ma, M.; Simoes de Souza, F.; Futia, G. L.; Anderson, S. R.; Riguero, J.; Tollin, D.; Gentile-Polese, A.; Platt, J. P.; Hiratani, N.; Gibson, E. A.; Restrepo, D.
10.1101/2023.10.01.560382 — neuroscience — Posted on 2023-10-22
1421 Introducing Isotopia: a stable isotope database for Classical Antiquity
Formichella, G.; Soncin, S.; Lubritto, C.; Tafuri, M. A.; Fernandes, R.; Cocozza, C.
10.1101/2023.10.19.563074 — paleontology — Posted on 2023-10-22
1422 Tetraspanin CD81 promotes leukemia stem cell function and represents a new therapeutic vulnerability in acute myeloid leukemia
Gonzales, F.; Peyrouze, P.; Boyer, T.; Guihard, S.; Sevrin, F.; LAURENT, D.; Plesa, A.; Barthelemy, A.; Bongiovanni, A.; Pottier, N.; PREUDHOMME, C.; DUPLOYEZ, N.; Berthon, C.; ROUMIER, C.; CHEOK, M.
10.1101/2023.09.20.558656 — cancer biology — Posted on 2023-10-22
1424 Automated Bioinformatics Analysis via AutoBA
Zhou, J.; Zhang, B.; Chen, X.; Li, H.; Xu, X.; Chen, S.; Gao, X.
10.1101/2023.09.08.556814 — bioinformatics — Posted on 2023-10-22
1430 A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms
McSwiggen, D. T.; Liu, H.; Tan, R.; Agramunt Puig, S.; Akella, L. B.; Berman, R.; Bretan, M.; Chen, H.; Darzacq, X.; Ford, K.; Godbey, R.; Gonzalez, E.; Hanuka, A.; Heckert, A.; Ho, J. J.; Johnson, S. L.; Kelso, R.; Klammer, A.; Krishnamurthy, R.; Li, J.; Lin, K.; Margolin, B.; McNamara, P.; Meyer, L.; Pierce, S. E.; Sule, A.; Stashko, C.; Tang, Y.; Anderson, D. J.; Beck, H.
10.1101/2023.01.05.522916 — cell biology — Posted on 2023-10-22
1432 Anti-CRISPR proteins trigger a burst of CRISPR-Cas9 expression that enhances phage defense
Workman, R. E.; Stoltzfus, M. J.; Keith, N. C.; Euler, C. W.; Bondy-Denomy, J.; Modell, J. W.
10.1101/2023.10.22.562561 — microbiology — Posted on 2023-10-22
1435 Spatial mapping of rheumatoid arthritis synovial niches reveals specific macrophage networks associated with response to therapy
De Lima, J.; Boutet, M.-A.; Bortolotti, O.; Chepeaux, L.-A.; Glasson, Y.; Dume, A.-S.; Le Pluart, A.; Nerviani, A.; Fossati-Jimack, L.; Michaud, H.-A.; Guicheux, J.; Le Goff, B.; Pitzalis, C.; Courties, G.; Apparailly, F.; Blanchard, F.
10.1101/2023.10.20.563040 — immunology — Posted on 2023-10-22
1437 Directional predictions of HIV transmission with optimised genomics in cohorts of serodiscordant couples
Zhao, L.; Hall, M.; Wymant, C.; Abeler-Dörner, L.; Otecko, N.; MacIntyre-Cockett, G.; Chaudron, S. E.; Thomson, L.; Golubchik, T.; Lingappa, J. R.; Ferretti, L.; Lythgoe, K.; Fraser, C.; Herbeck, J.; Bonsall, D.; PANGEA consortium, t.
10.1101/2023.10.19.563197 — genomics — Posted on 2023-10-22
1439 RNA Polymerase II-mediated transcription is required for repair of ribosomal DNA breaks in nucleolar caps, guarding against genomic instability
Checa-Rodriguez, C.; Suarez-Quintero, B.; Contreras, L.; Korsholm, L.; Payne-Larsen, D. H.; de la Cruz Diaz, J.; Bartek, J.; Gomez-Cabello, D.
10.1101/2023.10.20.563274 — cell biology — Posted on 2023-10-22
1440 Platelet-specific TGFβ1 deficiency aggravates atherosclerosis, vascular inflammation, and hypercholesterolemia in mice
Tan, S.; Sun, Y.; Sheng, Z.; Min, Y.; Gistera, A.; Zhang, J.; Ketelhuth, D. F. J.; Liao, W.; Andersson, J.; Hu, H.; Wang, M.; Hou, M.; Zhang, M.; Peng, J.; Ma, C.; Li, N.
10.1101/2023.10.20.563268 — cell biology — Posted on 2023-10-22
1441 ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin
Goto, N.; Suke, K.; Yonezawa, N.; Nishihara, H.; Sato, Y.; Kujirai, T.; Kurumizaka, H.; Yamagata, K.; Kimura, H.
10.1101/2023.10.20.563387 — cell biology — Posted on 2023-10-22
1442 ROCK1 activates mitochondrial fission leading to oxidative stress and muscle atrophy
Si, M.; Yu, R.; Lin, H.; Li, F.; Jung, S. Y.; Thomas, S.; Danesh, F.; Wang, Y.; Peng, H.; Hu, Z.
10.1101/2023.10.22.563469 — cell biology — Posted on 2023-10-22
1443 Epigenetic deregulation of IFN and WNT pathways in AT2 cells impairs alveolar regeneration (in COPD)
Prada, M. L.; Schwartz, U.; Pease, D. F.; Pohl, S. T.; Ackesson, D.; Li, R.; Behrendt, A.; Tamas, R.; Richter, M.; Muley, T.; Hey, J.; Espinet, E.; Heussel, C. P.; Warth, A.; Schneider, M.; Winter, H.; Herth, F.; Imbusch, C. D.; Brors, B.; Benes, V.; Wyatt, D.; Jurkowski, T. P.; Stahl, H. F.; Plass, C.; Jurkowska, R.
10.1101/2023.10.22.563483 — cell biology — Posted on 2023-10-22
1444 Mining the heparinome for cryptic antimicrobial peptides that selectively kill gram-negative bacteria
Sandin Garcia, D.; Valle, J.; Gomez, J.; Comas, L.; Larrosa, M. N.; Gonzalez, J. J.; Jimenez, M. A.; Andreu, D.; Torrent, M.
10.1101/2023.10.19.563059 — systems biology — Posted on 2023-10-22
1445 Pathway-based, reaction-specific annotation of disease variants for elucidation of molecular phenotypes
Orlic-Milacic, M.; Rothfels, K.; Matthews, L.; Wright, A.; Jassal, B.; Shamovsky, V.; Trinh, Q.; Gillespie, M.; Sevilla, C.; Tiwari, K.; Ragueneau, E.; Gong, C.; Stephan, R.; May, B.; Haw, R.; Weiser, J.; Beavers, D.; Conley, P.; Hermjakob, H.; Stein, L. D.; D'Eustachio, P.; Wu, G.
10.1101/2023.10.18.562964 — systems biology — Posted on 2023-10-22
1446 The grapevine ABC transporter B family member 15 (VvABCB15) is trans-resveratrol transporter out of grapevine cells
Martinez-Marquez, A.; Martins, V.; Selles-Marchart, S.; Geros, H. V.; Corchete, P.; Bru-Martinez, R.
10.1101/2023.10.20.563313 — plant biology — Posted on 2023-10-22
1447 NFAT5-dependent transcriptional stress control of endothelial cells prevents maladaptive remodeling of pulmonary arterioles in the hypoxic lung
Laban, H.; Siegmund, S.; Schlereth, K.; Brandenburg, L.; Trogisch, F. A.; Weigert, A.; De La Torre, C.; Abukiwan, A.; Mogler, C.; Hecker, M.; Kuebler, W. M.; Korff, T.
10.1101/2023.10.18.563022 — physiology — Posted on 2023-10-22
1450 In vitro phenotypic susceptibility of HIV-1 non-group M to CCR5 inhibitor (Maraviroc): TROPI-CO study
GRACIAS, S.; El Yaalaoui, I.; Visseaux, B.; charpentier, C.; Diane, D.; Martin, C.; Lermechain, F.; Plantier, J.-C.; Alessandri-Gradt, E.
10.1101/2023.10.20.563343 — microbiology — Posted on 2023-10-22
1451 The anti-obesity effect of fish oil in diet-induced obese mice occurs via the induction of heat production in brown but not white adipose tissue
Obo, T.; Hashiguchi, H.; Matsuda, E.; Kawade, S.; Ogiso, K.; Iwai, H.; Ataka, K.; Yasuda, O.; Arimura, A.; Deguchi, T.; Asakawa, A.; Nishio, Y.
10.1101/2023.10.19.563064 — animal behavior and cognition — Posted on 2023-10-22
1455 Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice.
Sun, L.; Lv, Z.; Chen, X.; Ye, R.; Tian, S.; Wang, C.; Xie, X.; Yan, L.; Yao, X.; Shao, Y.; Cui, S.; Chen, J.; Liu, J.
10.1101/2023.06.21.545885 — developmental biology — Posted on 2023-10-22
1456 Acquisition of Auditory Discrimination Mediated by Different Processes through Two Distinct Circuits Linked to the Lateral Striatum
Setogawa, S.; Okauchi, T.; Hu, D.; Wada, Y.; Hikishima, K.; Onoe, H.; Nishizawa, K.; Sakayori, N.; Miyawaki, H.; Kitanishi, T.; Mizuseki, K.; Cui, Y.; Kobayashi, K.
10.1101/2023.10.19.563198 — animal behavior and cognition — Posted on 2023-10-21
1457 The radiation of Austral teals and the evolution of flightlessness
Rosinger, H. S.; Kardialsky, O.; Kennedy, M.; Spencer, H. G.; Steiner, F. M.; Schlick-Steiner, B. C.; Rawlence, N.; Knapp, M.
10.1101/2023.10.19.563194 — evolutionary biology — Posted on 2023-10-21
1458 Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease
Horvath, V.; Garza, R.; Jonsson, M. E.; Johansson, P. A.; Adami, A.; Christoforidou, G.; Karlsson, O.; Castilla Vallmanya, L.; Gerdes, P.; Pandiloski, N.; Douse, C. H.; Jakobsson, J.
10.1101/2023.10.20.563233 — neuroscience — Posted on 2023-10-21
1459 Bilateral Intracortical Inhibition during Unilateral Motor Preparation and Sequence Learning
Hamel, R.; Waltzing, B. M.; Hinder, M. R.; McAllister, C. J.; Jenkinson, N.; Galea, J. M.
10.1101/2023.10.19.563212 — neuroscience — Posted on 2023-10-21
1461 Extracellular modulation of TREK-2 activity with nanobodies provides insights into the mechanism of K2P channel regulation
Rodstrom, K. E. J.; Cloake, A.; Sormann, J.; Baronina, A.; Ang, J.; Smith, K. H. M.; Pike, A. C. W.; Proks, P.; Schewe, M.; Holland-Kaye, I.; Elliott, J.; Pardon, E.; Baukrowitz, T.; Owens, R. J.; Newstead, S.; Steyaert, J.; Carpenter, E. P.; Tucker, S. J.
10.1101/2023.10.19.562917 — biophysics — Posted on 2023-10-21
1467 Thiolation-Based Protein-Protein Hydrogels for Improved Wound Healing
Liu, X.; Wang, J.; Guo, Z.; Shen, W.; Jia, Z.; Shuang, J.; Li, L.; Wang, J.; Wang, L.; Li, J.; Chen, Y.; Sun, Y.; Zhang, M.; Bai, J.; Wang, L.; Li, X.
10.1101/2023.10.19.563054 — bioengineering — Posted on 2023-10-21
1468 Multilevel Plasticity and Altered Glycosylation Drive Aggressiveness in Hypoxic and Glucose-Deprived Bladder Cancer Cells
Peixoto, A.; Ferreira, D.; Miranda, A.; Relvas-Santos, M.; Freitas, R.; Veth, T. S.; Brandao, A.; Ferreira, E.; Paulo, P.; Cardoso, M.; Gaiteiro, C.; Cotton, S.; Soares, J.; Lima, L.; Teixeira, F.; Ferreira, R.; Palmeira, C.; Heck, A. J.; Oliveira, M. J.; Silva, A. M.; Santos, L. L.; Ferreira, J. A.
10.1101/2023.10.21.561355 — biochemistry — Posted on 2023-10-21
1469 Links between behaviour and resistances to acute hyperthermia and hypoxia using rainbow trout isogenic lines
Lagarde, H.; LALLIAS, D.; Phocas, F.; Goardon, L.; Bideau, M.; Guyvarc'h, F.; Labbe, L.; Dupont-Nivet, M.; Cousin, X.
10.1101/2023.10.19.563047 — animal behavior and cognition — Posted on 2023-10-21
1470 Multi-locus CRISPRi targeting with a single truncated guide RNA
Moore, M. M.; Wekhande, S.; Issner, R.; Collins, A.; Liu, Y.; Javed, N.; Buenrostro, J. D.; Epstein, C. B.; Mattei, E.; Doench, J. G.; Bernstein, B. E.; Shoresh, N.; Najm, F. J.
10.1101/2023.10.20.563306 — molecular biology — Posted on 2023-10-21
1471 A neuron-specific microexon ablates the novel DNA-binding function of a histone H3K4me0 reader PHF21A
Porter, R. S.; Nagai, M.; An, S.; Gavilan, M. C.; Murata-Nakamura, Y.; Bonefas, K. M.; Zhou, B.; Dionne, O.; Manoj Manuel, J.; St-Germain, J.; Browning, L.; Laurent, B.; Cho, U.-S.; Iwase, S.
10.1101/2023.10.20.563357 — molecular biology — Posted on 2023-10-21
1474 Identification and full-genome assembly of novel Colorado potato beetle iflavirus and solinvi-like virus with SISPA Sequencing
Antonets, M. E.; Bodnev, S. A.; Rotskaya, U. N.; Kosman, E. S.; Tregubchak, T. V.; Bauer, T. V.; Azaev, M. S.; Kryukov, V. Y.; Antonets, D. V.
10.1101/2023.10.21.563391 — microbiology — Posted on 2023-10-21
1476 A bivalent Adenovirus-Vectored Vaccine induces a measurable humoral response, but does not protect cynomolgus macaques against a lethal challenge with Sudan virus
van Tol, S.; Fletcher, P.; Feldmann, F.; Mukesh, R. K.; Port, J. R.; Fischer, R. J.; Gallogly, S.; Schulz, J. E.; Roderick, J. F.; Makinson, R.; Carmody, A.; Myers, L.; Lovaglio, J.; Smith, B. J.; Okumura, A.; Shaia, C.; Saturday, G.; Marzi, A.; Munster, V. J.; van Doremalen, N.
10.1101/2023.10.20.563337 — microbiology — Posted on 2023-10-21
1477 Influenza A virus resistance to 4-fluorouridine coincides with viral attenuation in vitro and in vivo
Lieber, C. M.; Kang, H.-J.; Aggarwal, M.; Lieberman, N. A. P.; Sobolik, E. B.; Yoon, J.-J.; Natchus, M. G.; Cox, R.; Greninger, A. L.; Plemper, R. K.
10.1101/2023.10.20.563370 — microbiology — Posted on 2023-10-21
1478 Efficient formation and maintenance of humoral and CD4 T cell immunity targeting the viral capsid in acute-resolving hepatitis E infection
Csernalabics, B.; Marinescu, M. S.; Maurer, L.; Kelsch, L.; Werner, J.; Baumann, K.; Zoldan, K.; Panning, M.; Reuken, P.; Bruns, T.; Bengsch, B.; Neumann-Haefelin, C.; Hofmann, M.; Thimme, R.; Dao Thi, V. L.; Boettler, T.
10.1101/2023.10.19.563038 — immunology — Posted on 2023-10-21
1483 Addressing the dNTP bottleneck restricting prime editing activity
Ponnienselvan, K.; Liu, P.; Nyalile, T.; Oikemus, S.; Joynt, A. T.; Kelly, K.; Guo, D.; Chen, Z.; Lee, J. M.; Schiffer, C. A.; Emerson, C. P.; Lawson, N. D.; Watts, J. K.; Sontheimer, E. J.; Luban, J. J.; Wolfe, S. A.
10.1101/2023.10.21.563443 — biochemistry — Posted on 2023-10-21
1484 H2S preconditioning induces long-lived perturbations in O2 metabolism
Hanna, D. A.; Diessl, J.; Guha, A.; Kumar, R. A.; Andren, A.; Lyssiotis, C. A.; Banerjee, R.
10.1101/2023.10.20.563353 — biochemistry — Posted on 2023-10-21
1485 In Vitro Safety Signals for Potential Clinical Development of the Anti-Inflammatory Pregnane X Receptor Agonist FKK6
Dvorak, Z.; Vyhlidalov, B.; Pecinkov, P.; Li, H.; Anzenbacher, P.; spicakova, a.; anzenbacherova, e.; Chow, V.; LIU, J.; Krause, H.; Wilson, D. J.; Beres, T.; Tarkowski, P.; Chen, D.; Mani, S.
10.1101/2023.10.21.563410 — biochemistry — Posted on 2023-10-21
1487 Genome-wide CRISPR/Cas9 screen identifies MAT2A as a critical host factor for BK Polyomavirus
Caller, L.; Ho, S.; Brown, K.; Dupont, L.; Zaletel, T.; Beale, R.; Lehner, P. J.; Crump, C. M.
10.1101/2023.10.20.563362 — microbiology — Posted on 2023-10-21
1488 Does phasic dopamine release cause policy updates?
Carter, F.; Cossette, M.-P.; Trujillo-Pisanty, I.; Pallikaras, V.; Breton, Y.-A.; Conover, K.; Caplan, J.; Solis, P.; Voisard, J.; Yaksich, A.; Shizgal, P.
10.1101/2022.08.08.502043 — neuroscience — Posted on 2023-10-21
1489 Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant
Tsujino, S.; Deguchi, S.; Nomai, T.; Padilla-Blanco, M.; Plianchaisuk, A.; Wang, L.; Begum, M. M.; Uriu, K.; Mizuma, K.; Nao, N.; Kojima, I.; Tsubo, T.; Li, J.; Matsumura, Y.; Nagao, M.; Oda, Y.; Tsuda, M.; Anraku, Y.; Kita, S.; Yajima, H.; Tabata, K.; Guo, Z.; Hinay, A. A.; Yoshimatsu, K.; Yamamoto, Y.; Nagamoto, Y.; Asakura, H.; Nagashima, M.; Sadamasu, K.; Yoshimura, K.; Nasser, H.; Jonathan, M.; Putri, O.; Kim, Y.; Chen, L.; Suzuki, R.; Tamura, T.; Maenaka, K.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Irie, T.; Matsuno, K.; Tanaka, S.; Ito, J.; Ikeda, T.; Takayama, K.; Za
10.1101/2023.10.19.563209 — microbiology — Posted on 2023-10-21
1490 Integrative multi-dimensional characterization of striatal projection neuron heterogeneity in adult brain
Gayden, J.; Puig, S.; Srinivasan, C.; Phan, B. N.; Abdelhady, G.; Buck, S. A.; Gamble, M. C.; Tejeda, H. A.; Dong, Y.; Pfenning, A. R.; Logan, R.; Freyberg, Z.
10.1101/2023.05.04.539488 — neuroscience — Posted on 2023-10-21
1492 Scope+: An open source generalizable architecture for single-cell atlases at sample and cell levels
Yin, D.; Cao, Y.; Chen, J.; Mak, C. L. Y.; Yu, K. H. O.; Lin, Y.; Zhang, J.; Li, J.; Ho, J. W. K.; Yang, J. Y. H.
10.1101/2022.12.03.518997 — bioinformatics — Posted on 2023-10-21
1493 Biodesign of Frugal CRISPR Kits for Equitable and Accessible Education
Collins, M. C.; Lau, M. B.; Ma, W.; Shen, A.; La Russa, M.; Qi, L. S.
10.1101/2023.10.14.562372 — bioengineering — Posted on 2023-10-21
1494 Transcription factor stoichiometry, motif affinity and syntax regulate single-cell chromatin dynamics during fibroblast reprogramming to pluripotency
Nair, S.; Ameen, M.; Sundaram, L.; Pampari, A.; Schreiber, J.; Balsubramani, A.; Wang, Y. X.; Burns, D.; Blau, H. M.; Karakikes, I.; Wang, K. C.; Kundaje, A.
10.1101/2023.10.04.560808 — genetics — Posted on 2023-10-21
1498 Emergent Ecological Patterns and Modelling of Gut Microbiomes in Health and in Disease
Pasqualini, J.; Facchin, S.; Rinaldo, A.; Maritan, A.; Savarino, E.; Suweis, S.
10.1101/2023.10.19.563037 — ecology — Posted on 2023-10-21
1506 Multiplexed CRISPR/Cas9 mutagenesis of rice PSBS1 non-coding sequences for transgene-free overexpression
Patel-Tupper, D.; Kelikian, A.; Leipertz, A.; Maryn, N.; Tjahjadi, M.; Karavolias, N. G.; Cho, M.-J.; Niyogi, K. K.
10.1101/2023.10.20.563333 — plant biology — Posted on 2023-10-21
1507 Characterization of the cryptic interspecific hybrid Lemna x mediterranea by an integrated approach provides new insights into duckweed diversity
Braglia, L.; Ceschin, S.; Iannelli, M. A.; Bog, M.; Fabriani, M.; Frugis, G.; Gavazzi, F.; Giani, S.; Mariani, F.; Muzzi, M.; Pelella, E.; Morello, L. E. M.
10.1101/2023.10.19.562947 — plant biology — Posted on 2023-10-21
1509 HIF-1 inactivation empowers HIF-2 to drive hypoxia adaptation in aggressive forms of medulloblastoma
Contenti, J.; Guo, Y.; Larcher, M.; Mirabal-Ortega, L.; ROULEAU, M.; Irondelle, M.; Tiroille, V.; Mazzu, A.; Duranton-Tanneur, V.; Pedeutour, F.; Ben-Sahra, I.; Lago, C.; Leva, G.; Tiberi, L.; Robert, G.; Pouponnot, C.; Bost, F.; Mazure, N. M.
10.1101/2023.10.17.562750 — cancer biology — Posted on 2023-10-21
1510 Patient-derived tumor organoids from resected non-small cell lung cancers for high-throughput response testing with approved and repurposed drugs
Suvilesh, K. N.; Manjunath, Y.; Nussbaum, Y. I.; Gadelkarim, M.; Srivastava, A.; Li, G.; Warren, W. C.; Shyu, C.-R.; Gao, F.; Ciorba, M.; Mitchem, J. B.; Rachagani, S.; Kaifi, J. T.
10.1101/2023.10.18.562944 — cancer biology — Posted on 2023-10-21
1512 Differential effects of follicle-stimulating hormone glycoforms on the transcriptome profile of cultured rat granulosa cells as disclosed by RNA-seq
Ulloa-Aguirre, A.; Zarinan, T.; Espinal-Enriquez, J.; De anda-Jauregui, G.; Lira-Albarran, S.; Hernandez-Montes, G.; Rebollar-Vega, R.; Bousfield, G. R.; Butnev, V.; Hernandez-Lemus, E.
10.1101/2023.10.18.562995 — genomics — Posted on 2023-10-21
1513 Co-existence of blaKPC-2 and blaVIM-2 in highly carbapenem-resistant Pseudomonas aeruginosa isolated in the ICU of a public hospital
Wang, Z.; Zheng, L.; Guan, J.-y.; Yang, Y.; Chen, P.; Li, Q.; Guo, X.; Zhu, L.; Lu, G.; Jing, J.; Sun, S.; Ji, X.; sun, y.; Jiang, B.; Guo, J.
10.1101/2023.10.18.562919 — genomics — Posted on 2023-10-21
1515 Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in mouse embryos
Schöler, H. R.; Hou, Y.; Nie, Z.; Velychko, S.; Bedzhov, I.; Heising, S.; Jiang, Q.; Zhang, H.; Wu, G.; Adachi, K.
10.1101/2023.10.18.562912 — developmental biology — Posted on 2023-10-21
1519 C9ORF72 deficiency results in degeneration of the zebrafish retina in vivo
Jaroszynska, N.; Salzinger, A.; Tsarouchas, T.; Becker, C. G.; Becker, T.; Lyons, D.; MacDonald, R. B.; Keatinge, M.
10.1101/2023.10.19.563041 — neuroscience — Posted on 2023-10-21
1520 Inhibition of dipeptidyl peptidase 4 allows accurate measurement of GLP-1 secretion in mice
Smits, M. M.; Galsgaard, K. D.; Jepsen, S. L.; Wewer Albrechtsen, N.; Hartmann, B.; Holst, J. J.
10.1101/2023.10.19.563029 — physiology — Posted on 2023-10-21
1523 Microsporidia Ser/Thr Protein Phosphatase PP1 Targets DCs MAPK Pathway and Impairs Immune Functions
Bao, J.; Tang, Y.; Chen, Y.; Jin, J.; Wang, X.; An, G.; Cao, L.; Zhang, H.; Cheng, G.; Pan, G.; Zhou, Z.
10.1101/2023.09.13.557560 — microbiology — Posted on 2023-10-21
1527 Response to photic stimulation as a measure of cortical excitability in epilepsy patients
Vranic-Peters, M. J.; O'brien, P.; Seneviratne, U.; Reynolds, A.; Lai, A.; Grayden, D. B.; Cook, M.; Peterson, A.
10.1101/2023.04.23.537976 — neuroscience — Posted on 2023-10-21
1529 ATF4 Dependent Increase in Mitochondrial-Endoplasmic Reticulum Tethering Following OPA1 Deletion in Skeletal Muscle
Hinton, A.; Katti, P.; Mungai, M.; Hall, D.; Koval, O.; Shao, J.; Vue, Z.; Lopez, E. G.; Rostami, R.; Neikirk, K.; Ponce, J.; Streeter, J.; Schickling, B.; Bacevac, S.; Grueter, C.; Marshall, A.; Beasley, H. K.; DoKoo, Y.; Bodine, S.; Nava, N. G. R.; Quintana, A.; Song, L.-S.; Grumbach, I.; Pereira, R. O.; Glancy, B.; Abel, E. D.
10.1101/2022.09.12.507669 — biophysics — Posted on 2023-10-21
1532 Trophic Efficiency Facilitates Larval Shortbelly Rockfish (Sebastes jordani) Development
Kwan, G. T.; Walsh, K. A.; Thompson, A. R.; Ben-Aderet, N. J.; Fennie, H. W.; Semmens, B. X.; Swalethorp, R.
10.1101/2023.10.18.562988 — ecology — Posted on 2023-10-21
1533 Fine needle aspiration of human lymph nodes reveals cell populations and soluble interactors pivotal to immunological priming
Provine, N. M.; Al-Diwani, A.; Agarwal, D.; Dooley, K.; Heslington, A.; Murchison, A. G.; Garner, L.; Sheerin, F.; Klenerman, P.; Irani, S. R.
10.1101/2023.10.18.562983 — immunology — Posted on 2023-10-21
1534 Paradox Found: Global Accounting of Lymphocyte Protein Synthesis
Seedhom, M.; Dersh, D.; Holly, J.; Pavon-Eternod, M.; Wei, J.; Shores, L.; David, A.; Santos, J.; Hickman, H.; Yewdell, J.
10.1101/2022.10.31.514539 — immunology — Posted on 2023-10-21
1536 Effects of non-retinal inputs in visual thalamus depend on visual responsiveness and stimulus context
Schmors, L.; Kotkat, A.; Bauer, Y.; Huang, Z.; Crombie, D.; Meyerolbersleben, L.; Sokoloski, S.; Berens, P.; Busse, L.
10.1101/2023.10.18.562960 — neuroscience — Posted on 2023-10-21
1537 Accelerated Aging after Traumatic Brain Injury: an ENIGMA Multi-Cohort Mega-Analysis
Dennis, E. L.; Vervoordt, S.; Adamson, M. M.; Amiri, H.; Bigler, E.; Caeyenberghs, K.; Cole, J. H.; Dams-O'Connor, K.; Deutscher, E. M.; Dobryakova, E.; Genova, H. M.; Grafman, J. H.; Haberg, A. K.; Hellstrom, T.; Irimia, A.; Koliatsos, V. E.; Lindsey, H. M.; Livny, A.; Menon, D. K.; Merkley, T. L.; Mohamed, A. Z.; Mondello, S.; Monti, M. M.; Newcombe, V. F.; Newsome, M. R.; Ponsford, J.; Rabinowitz, A.; Smevik, H.; Spitz, G.; Venkatesan, U.; Westlye, L. T.; Zafonte, R.; Thompson, P. M.; Wilde, E. A.; Olsen, A.; Hillary, F. G.
10.1101/2023.10.16.562638 — neuroscience — Posted on 2023-10-21
1539 NeurostimML: A machine learning model for predicting neurostimulation-induced tissue damage
Li, Y.; Frederick, R. A.; George, D.; Cogan, S. F.; Pancrazio, J. J.; Bleris, L.; Hernandez-Reynoso, A. G.
10.1101/2023.10.18.562980 — neuroscience — Posted on 2023-10-21
1541 Androgen blockade primes NLRP3 in macrophages to induce tumor phagocytosis
Chaudagar, K. K.; Srikrishnan, R.; Mei, S.; Hirz, T.; Hu, Y.-M.; Argulian, A.; Labadie, B.; Desai, K.; Grimaldo, S.; Kahramangil, D.; Nair, R.; D Souza, S.; Zhou, D.; Li, M.; Doughan, F.; Chen, R.; Shafran, J.; Loyd, M.; Xia, Z.; Sykes, D. B.; Moran, A. E.; Patnaik, A.
10.1101/2023.09.15.557996 — cancer biology — Posted on 2023-10-21
1542 Bone Morphogenetic Protein (BMP) signaling upregulates expression of ID1 and ID3 in pancreatitis and pancreatic ductal adenocarcinoma
Raghunathan, M. K.; Scully, K. M.; Wehrmaker, A.; Murad, R.; Lowy, A. M.; Maurer, H. C.; DelGiorno, K. E.; Itkin-Ansari, P.
10.1101/2023.09.01.555987 — cancer biology — Posted on 2023-10-21
1549 ABC-HuMi: the Atlas of Biosynthetic Gene Clusters in the Human Microbiome
Hirsch, P.; Tagirdzhanov, A.; Kushnareva, A.; Olkhovskii, I.; Graf, S.; Schmartz, G. P.; Hegemann, J.; Bozhueyuek, K.; Mueller, R.; Keller, A.; Gurevich, A.
10.1101/2023.09.18.558305 — bioinformatics — Posted on 2023-10-21
1552 Identification of pharmacological inducers of a reversible hypometabolic state for whole organ preservation
Sperry, M. M.; Charrez, B.; Fotowat, H.; Gardner, E.; Pilobello, K.; Izadifar, Z.; Lin, T.; Kuelker, A.; Kaki, S.; Lewandowski, M.; Lightbown, S.; Martinez, R.; Marquez, S.; Moore, J.; Plaza-Oliver, M.; Sesay, A.; Shcherbina, K.; Sheehan, K.; Takeda, T.; Del Campo, D.; Andrijauskaite, K.; Cisneros, E.; Lopez, R.; Cano, I.; Maxwell, Z.; Jessop, I.; Veraza, R.; Bunegin, L.; Percival, T. J.; Weitzel, E.; Sleeter, J. J.; Parry, O. G.; Yracheta, J.; Pena, J. J.; Wood, D. M.; Homas, Z. T.; Hinshaw, C. J.; Cox-Hinshaw, J.; Levin, M.; Super, M.; Novak, R.; Ingber, D. E.
10.1101/2023.02.27.530270 — bioengineering — Posted on 2023-10-21
1554 Foot orientation and trajectory variability in locomotion: effects of real-world terrain
Gibson, E.; Douglas, G.; Jeffries, K.; Delaurier, J.; Chestnut, T.; Charlton, J. M.
10.1101/2023.10.18.562999 — bioengineering — Posted on 2023-10-21
1556 Short-stranded zein fibers for muscle tissue engineering in alginate-based hydrogels
Melzener, L.; Spaans, S.; Hauck, N.; Potgens, A. J.; Flack, J. E.; Post, M. J.; Dogan, A.
10.1101/2023.10.18.562894 — bioengineering — Posted on 2023-10-21
1557 AlphaFold2 can predict single-mutation effects
Mcbride, J. M.; Reinharz, V.; Polev, K.; Grzybowski, B. A.; Tlusty, T.
10.1101/2022.04.14.488301 — biochemistry — Posted on 2023-10-21
1558 Rapid and Signal Crowdedness-Robust In-Situ Sequencing through Hybrid Block Coding
Chang, T.; Han, W.; Jiang, M.; Li, J.; Liao, Z.; Tang, M.; Zhang, J.; Shen, J.; Chen, Z.; Fei, P.; Ren, X.; Pang, Y.; Wang, G.; Wang, J.; Huang, Y.
10.1101/2022.11.16.516714 — genomics — Posted on 2023-10-21
1559 Collagen IV of basement membranes: I. Origin and diversification of COL4 genes enabling animal evolution
Page-McCaw, P. S.; Pokidysheva, E. N.; Darris, C. E.; Chetyrkin, S.; Murawala, P.; Gallup, J.; Aspirnauts, ; Hudson, J. K.; Hudson, B. G.
10.1101/2023.10.18.563013 — genomics — Posted on 2023-10-21
1562 Phylogenomics, biogeography, and trait evolution of the Boletaceae (Boletales, Agaricomycetes, Basidiomycota)
Tremble, K.; Henkel, T.; Bradshaw, A.; Domnauer, C.; Furci, G.; Tham, L. X.; Aime, C.; Moncalvo, J.-M.; Dentinger, B.
10.1101/2023.10.18.563010 — evolutionary biology — Posted on 2023-10-21
1563 Cooperation between bacteriocytes and endosymbionts drives function and development of symbiotic cells in mussel holobionts
Chen, H.; Li, M.; Zhong, Z.; Wang, M.; Lian, C.; Han, G.; Wang, H.; Zhou, L.; Zhang, H.; Cao, L.; LI, C.
10.1101/2023.08.18.553804 — ecology — Posted on 2023-10-21
1566 Phase separation of Myc differentially regulates gene transcription
Yang, J.; Chung, C.-I.; Koach, J.; Liu, H.; Navalkar, A.; Ma, Z.; Zhao, Q.; Yang, X.; Mittag, T.; Shen, Y.; Weiss, W. A.; Shu, X.
10.1101/2022.06.28.498043 — cell biology — Posted on 2023-10-21
1567 A murine model of Trypanosoma brucei-induced myocarditis and cardiac dysfunction
Crilly, N.; Zita, M. D.; Beaver, A.; Sysa-Shah, P.; Bhalodia, A.; Gabrielson, K.; Adamo, L.; Mugnier, M.
10.1101/2023.10.05.560950 — microbiology — Posted on 2023-10-21
1568 Convergence, plasticity, and tissue residence of regulatory T cell response via TCR repertoire prism
Nakonechnaya, T. O.; Moltedo, B.; Putintseva, E. V.; Leyn, S.; Bolotin, D. A.; Britanova, O. V.; Shugay, M.; Chudakov, D. M.
10.1101/2023.06.15.544726 — immunology — Posted on 2023-10-21
1569 Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt
Erice, P. A.; Huang, X.; Seasock, M. J.; Robertson, M. J.; Tung, H.-Y.; Perez-Negron, M. A.; Lotlikar, S. L.; Corry, D.; Kheradmand, F.; Rodriguez, A.
10.1101/2023.10.12.562059 — immunology — Posted on 2023-10-21
1572 Spindle Chirp and other Sleep Oscillatory Features in Young Children with Autism
Cumming, D.; Kozhemiako, N.; Thurm, A.; Farmer, C.; Purcell, S.; Buckley, A.
10.1101/2023.06.15.545095 — neuroscience — Posted on 2023-10-21
1575 Dopamine projections to the basolateral amygdala drive the encoding of identity-specific reward memories
Sias, A. C.; Jafar, Y.; Goodpaster, C. M.; Ramirez-Armenta, K.; Wrenn, T. M.; Griffin, N. K.; Patel, K.; Lamparelli, A. C.; Sharpe, M. J.; Wassum, K. M.
10.1101/2022.09.26.509602 — neuroscience — Posted on 2023-10-21
1576 Mobile brain imaging in butoh dancers: from rehearsals to public performance
Theofanopoulou, C.; Paez, S.; Huber, D.; Todd, E.; Ramirez-Moreno, M. A.; Khaleghian, B.; Sanchez, A. M.; Barcelo, L.; Gand, V.; Contreras-Vidal, J. L.
10.1101/2023.02.26.530087 — neuroscience — Posted on 2023-10-21
1577 Towards a species-level phylogeny for Neotropical Myrtaceae: notes on topology and resources for future studies
The Neotropical Myrtaceae Working Group, ; Staggemeier, V.; Amorim, B.; Bunger, M.; R. Costa, I.; Quintino de Faria, J. E.; Flickinger, J.; Giaretta de Oliveira, A.; T. Kubo, M.; Fernandes Lima, D.; Lima dos Santos, L.; Lourenco, A. R.; Lucas, E.; Mazine, F.; Murillo-A, J.; I.U.Oliveira, M.; Parra-O, C.; E.B.Proenca, C.; Reginato, M.; O.Rosa, P.; F. Santos, M.; Stadnik, A.; C. Tuler, A.; Sampaio Valdemarin, K.; Vasconcelos, T.
10.1101/2023.10.18.562956 — plant biology — Posted on 2023-10-21
1579 Cross-species imputation and comparison of single-cell transcriptomic profiles
Zhang, R.; Yang, M.; Schreiber, J.; ODay, D. R.; Turner, J.; Shendure, J.; Disteche, C. M.; Deng, X.; Noble, W. S.
10.1101/2023.10.19.563173 — bioinformatics — Posted on 2023-10-20
1582 40 Hz Steady-State Responses in Human Auditory Cortex Depend on GABAergic Neuronal Inhibition
Toso, A.; Wermuth, A. P.; Arazi, A.; Braun, A.; Grent-'t Jong, T.; Uhlhaas, P. J.; Donner, T. H.
10.1101/2023.10.20.563259 — neuroscience — Posted on 2023-10-20
1590 Open-top Bessel beam two-photon light sheet microscopy for three-dimensional pathology
Park, W. Y.; Yun, J.; Shin, J.; Oh, B. H.; Yoon, G.; Hong, S.-M.; Kim, K. H.
10.1101/2023.10.18.562941 — pathology — Posted on 2023-10-20
1592 The Unexpected Functional Diversity of Photoexcited NAD
Kufner, C. L.; Janicki, M. J.; Lozano, G. G.; Sasselov, D. D.
10.1101/2023.10.19.563164 — biophysics — Posted on 2023-10-20
1593 Single-Molecule Morphology of Topologically Digested Olympic Networks
Ramakrishnan, S.; Chen, Z.; Michieletto, D.; Savill, N.; Schnaufer, A.; Tubiana, L.; Fosado, Y.; Vanderlinden, W.
10.1101/2023.10.18.562933 — biophysics — Posted on 2023-10-20
1594 Synthesis of pyrazole-based macrocycles leads to a highly selective inhibitor for MST3
Amrhein, J. A.; Berger, L. M.; Balourdas, D.-I.; Joerger, A. C.; Menge, A.; Kraemer, A.; Frischkorn, J. M.; Berger, B.-T.; Elson, L.; Kaiser, A.; Schubert-Zsilavecz, M.; Mueller, S.; Knapp, S.; Hanke, T.
10.1101/2023.10.20.563248 — biochemistry — Posted on 2023-10-20
1595 Deletion of NuRD component Mta2 in nephron progenitor cells causes developmentally programmed FSGS
Basta, J.; Robbins, L.; Stout, L.; Brennan, M.; Shapiro, J.; Chen, M.; Denner, D.; Baldan, A.; Messias, N.; Madhavan, S. M.; Parikh, S. V.; Rauchman, M.
10.1101/2023.10.18.562984 — developmental biology — Posted on 2023-10-20
1596 The widely used Ucp1-CreEvdr transgene elicits complex developmental and metabolic phenotypes.
Halurkar, M. S.; Inoue, O.; Mukherjee, R.; Bonatto Paese, C. L.; Duszynski, M.; Brugmann, S. C.; Lim, H.-W.; Sanchez-Gurmaches, J.
10.1101/2023.10.20.563165 — molecular biology — Posted on 2023-10-20
1598 Terpenoid balance in Aspergillus nidulans unveiled by heterologous squalene synthase expression
Park, S. C.; Steffan, B. N.; Lim, F. Y.; Gupta, R.; Butun, F. A.; Chen, H.; Ye, R.; Decker, T.; Wu, C. C.; Kelleher, N. L.; Bok, J. W.; Keller, N. P.
10.1101/2023.10.20.563295 — microbiology — Posted on 2023-10-20
1599 The function of CozE proteins is linked to lipoteichoic acid biosynthesis in Staphylococcus aureus
Barbuti, M. D.; Lambert, E.; Myrbraten, I. S.; Ducret, A.; Stamsas, G. A. H.; Wilhelm, L.; Liu, X.; Salehian, Z.; Veening, J.-W.; Straume, D.; Grangeasse, C.; Perez, C.; Kjos, M.
10.1101/2023.10.20.563254 — microbiology — Posted on 2023-10-20
1601 Conversion of aromatic compounds from fractionated industrial hydrolysis lignin by Pseudomonas putida and environmental strains
Morehead, P. A.; Vider, H.; Murk, C.; Viggor, S.; Joesaar, M.; Bottoms, S.; Salmar, S.; Kivisaar, M.; Loog, M.
10.1101/2023.10.19.563119 — microbiology — Posted on 2023-10-20
1602 ALCAM-mediated synapses between DC1 and CD8 T cells are inhibited in advanced lung tumors
Morosi, L. G.; Piperno, G. M.; Joshi, S.; Amadio, R.; Vodret, S.; Lopez-Rodriguez, L.; Benvenuti, F.
10.1101/2023.10.18.562940 — immunology — Posted on 2023-10-20
1603 Sustainable production of 2,3,5,6-Tetramethylpyrazine at high titer in engineered Corynebacterium glutamicum using statistical design of experiments
Srinivasan, A.; Chen-Xiao, K.; Banerjee, D.; Oka, A.; Pidatala, V. R.; Eudes, A.; Simmons, B. A.; Eng, T. T.; Mukhopadhyay, A.
10.1101/2023.10.20.563186 — synthetic biology — Posted on 2023-10-20
1604 Constraints on Lanthanide Separation by Selective Biosorption
Anderson, C.; Medin, S.; Adair, J.; Demopoulos, B.; Eneli, E.; Kuelbs, C.; Lee, J. J.; Sheppard, T. J.; Sinar, D.; Thurston, Z.; Xu, M.; Zhang, K.; Barstow, B.
10.1101/2023.10.18.562985 — synthetic biology — Posted on 2023-10-20
1610 Transporter-mediated depletion of extracellular proline directly contributes to plant pattern-triggered immunity against a bacterial pathogen
Rogan, C. J.; Pang, Y.-Y.; Mathews, S. D.; Turner, S. E.; Weisberg, A. J.; Lehmann, S.; Rentsch, D.; Anderson, J. C.
10.1101/2023.10.18.562815 — plant biology — Posted on 2023-10-20
1615 Daylong Acoustic Recordings of Grazing and Rumination Activities in Dairy Cows
Martinez Rau, L. S.; Chelotti, J. O.; Ferrero, M.; Galli, J.; Utsumi, S.; Planisich, A.; Vignolo, L.; Giovanini, L.; Rufiner, H. L.
10.1101/2023.10.18.562979 — animal behavior and cognition — Posted on 2023-10-20
1617 Nutritional sex-specificity during larval development in mosquitoes
Romoli, O.; Serrato-Salas, J.; Gapp, C.; Figueras Ivern, P.; Gendrin, M.
10.1101/2023.10.18.562973 — developmental biology — Posted on 2023-10-20
1618 Biosynthesis of H-GDGTs linked to ocean oxygen deficiency
Li, Y.; Yu, T.; Feng, X.; Zhao, B.; Chen, H.; Connock, G. T.; Liu, X.-L.; Yang, H.; Kaiser, J.; Wittenborn, A. K.; Dong, L.; Wang, F.; Anderson, H. R.; Burns, N. Z.; Zeng, F.; Tao, L.; Zeng, Z.
10.1101/2023.10.20.562873 — microbiology — Posted on 2023-10-20
1619 Pathogenic CD8 T cell responses are driven by neutrophil-mediated hypoxia in cutaneous leishmaniasis.
Fowler, E. A.; Farias Amorim, C.; Mostacada, K.; Yan, A.; Amorim Sacramento, L.; Stanco, R. A.; Hales, E. D. S.; Varkey, A.; Zong, W.; Wu, G. D.; de Oliveira, C. I.; Collins, P. L.; Novais, F. O.
10.1101/2023.10.18.562926 — immunology — Posted on 2023-10-20
1621 Neuroinflammation in post-acute sequelae of COVID-19 (PASC) as assessed by PBR28 PET correlates with vascular disease measures
VanElzakker, M. B.; Bues, H. F.; Brusaferri, L.; Kim, M.; Saadi, D.; Ratai, E.-M.; Dougherty, D. D.; Loggia, M. L.
10.1101/2023.10.19.563117 — neuroscience — Posted on 2023-10-20
1623 Efficient axonal trafficking of endolysosomes depends on the balanced ratio of microtubule tyrosination and detyrosination
Konietzny, A.; Peris, L.; Han, Y.; Popp, Y.; Bommel, B. v.; Sharma, A.; Delagrange, P.; Arbez, N.; Moutin, M.-J.; Mikhaylova, M.
10.1101/2023.10.18.562903 — neuroscience — Posted on 2023-10-20
1625 The type of carbon source not the growth rate it supports can determine diauxie
Huo, Y.; Danecka, W.; Farquhar, I.; Mailliet, K.; Moses, T.; Wallace, E. W.; Swain, P. S.
10.1101/2023.10.18.562896 — systems biology — Posted on 2023-10-20
1632 Zinc-finger (ZiF) fold secreted effectors form a functionally diverse family across lineages of the blast fungus Magnaporthe oryzae.
Concepcion, J. C. D. l.; Langner, T.; Fujisaki, K.; Were, V.; Yan, X.; Lam, A. H. C.; Saado, I.; Brabham, H.; Win, J.; Yoshida, K.; Talbot, N. J.; Terauchi, R.; Kamoun, S.; Banfield, M. J.
10.1101/2023.10.18.562914 — plant biology — Posted on 2023-10-20
1633 A precise balance of TETRASPANIN1/TORNADO2 activity is required for vascular proliferation and ground tissue patterning in Arabidopsis
Konstantinova, N.; Mor, E.; Verhelst, E.; Nolf, J.; Vereecken, K.; Wang, F.; Van Damme, D.; De Rybel, B.; Glanc, M.
10.1101/2023.10.18.562921 — plant biology — Posted on 2023-10-20
1634 Open-source LED lamp for the LI-6800 photosynthesis system
Velez-Ramirez, A. I.; Moreno, J. d. D.; Perez-Guerrero, U. G.; Juarez, A. M.; Castillo-Arriaga, H.; Vazquez-Medrano, J.; Hernandez-Morales, I.
10.1101/2023.10.18.562806 — plant biology — Posted on 2023-10-20
1635 Detecting the genetic variants associated with key culinary traits in Dioscorea alata
Dossa, K.; Houngbo, M. E.; Lechaudel, M.; Maledon, E.; Zoclanclounon, Y. A. B.; Irep, J. L.; Nasir, M. F.; Chair, H.; Cornet, D.
10.1101/2023.10.18.562904 — plant biology — Posted on 2023-10-20
1636 UPR pathway is required for Arabidopsis thaliana resistance to necrophic fungal pathogens.
Blanchard, C.; Aime, S.; Ducloy, A.; Hichami, S.; Azzopardi, M.; Cacas, J.-L.; Lamotte, O.
10.1101/2023.10.18.562849 — plant biology — Posted on 2023-10-20
1637 The impact of light and thioredoxins on the plant thiol-disulfide proteome
Hou, L.-Y.; Sommer, F. K.; Poeker, L.; Dziubek, D.; Schroda, M.; Geigenberger, P.
10.1101/2023.10.17.562744 — plant biology — Posted on 2023-10-20
1639 Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan
Bomba-Warczak, E. K.; Velez, K. M.; Zhou, L. T.; Guillermier, C.; Edassery, S.; Steinhauser, M.; Savas, J. N.; Elizabeth Duncan, F.
10.1101/2023.10.18.562852 — physiology — Posted on 2023-10-20
1640 Ribosomal S6 kinase 1 regulates inflammaging via the senescence secretome
Gallage, S.; Irvine, E. E.; Pedroni, S.; Barragan Avila, J. E.; Khadayate, S.; Pombo, J.; Brookes, S.; Heide, D.; Dharmalingam, G.; Choudhury, A. I.; Herranz, N.; Vernia, S.; Heikenwalder, M.; Gil, J.; Withers, D. J.
10.1101/2023.10.17.562098 — physiology — Posted on 2023-10-20
1642 Aging and intraocular pressure homeostasis in mice
Li, G.; van Batenburg-Sherwood, J.; Safa, B. N.; Fraticelli Guzman, N. S.; Wilson, A.; Bahrani Fard, M. R.; Choy, K.; de Ieso, M. L.; Cui, S.; Feola, A. J.; Weisz, T.; Kuhn, M.; Bowes Rickman, C.; Farsiu, S.; Ethier, C. R.; Stamer, W. D.
10.1101/2023.10.17.562768 — physiology — Posted on 2023-10-20
1647 Towards Parsimonious Generative Modeling of RNA Families
Calvanese, F.; Lambert, C. N.; Nghe, P.; Zamponi, F.; Weigt, M.
10.1101/2023.10.19.562525 — bioinformatics — Posted on 2023-10-20
1648 Transepithelial Electrical Impedance Increase Following Porous Substrate Electroporation Enables Label-Free Delivery
Brooks, J. R.; Heiman, T. C.; Lorenzen, S. R.; Mungloo, I.; Mirfendereski, S.; Park, J. S.; Yang, R.
10.1101/2023.10.17.562630 — bioengineering — Posted on 2023-10-20
1649 Long-Term In Vivo Molecular Monitoring Using Aptamer-Graphene Microtransistors
Wu, G.; Zhang, E. T.; Qiang, Y.; Esmonde, C.; Chen, X.; Wei, Z.; Song, Y.; Zhang, X.; Schneider, M. J.; Li, H.; Sun, H.; Weng, Z.; Santaniello, S.; He, J.; Lai, R. Y.; Li, Y.; Bruchas, M. R.; Zhang, Y.
10.1101/2023.10.18.562080 — bioengineering — Posted on 2023-10-20
1650 Highly pathogenic Avian Influenza A (H5N1) Clade 2.3.4.4b in Wild Birds, Ecuador.
Carrazco-Montalvo, A.; Luje, L.; Rodriguez-Polit, C.; Ampuno, A.; Patino, L.; Gutierrez-Pallo, D.; Alava, D.; Alarcon-Vallejo, D.; Argüello, N.; Echeverria-Garces, G.; De La Torre, D.
10.1101/2023.10.18.562614 — genomics — Posted on 2023-10-20
1652 Genetic deficiency of ribosomal rescue factor HBS1L causes retinal dystrophy associated with Pelota and EDF1 depletion
LUO, S.; AlWattar, B.; Li, Q.; Bora, K.; Blomfield, A. K.; Lin, J.; Fulton, A.; Chen, J.; Agrawal, P. B.
10.1101/2023.10.18.562924 — genetics — Posted on 2023-10-20
1653 Chondrodysplasia-inducing COL2A1 p.Gly1170Ser causes an ER storage defect without associated unfolded protein response in a human cartilage model
Yammine, K. M.; Abularach, S. M.; Kim, S.-y.; Bikovtseva, A. A.; Lilianty, J.; Butty, V. L.; Schiavoni, R. P.; Bateman, J. F.; Lamande, S. R.; Shoulders, M. D.
10.1101/2023.10.19.562780 — genetics — Posted on 2023-10-20
1657 A fast and reliable larval sampling method for improving the monitoring of fruit flies in soft and stone fruits
Zriki, G.; Blois, R.; Fournier, C.; Tregoat-Bertrand, L.; Poupart, P.-Y.; Bardel, A.; Gard, B.; Rode, N. O.
10.1101/2023.10.18.562869 — ecology — Posted on 2023-10-20
1658 Threat of mining to African great apes
Junker, J.; Quoss, L.; Valdez, J.; Arandjelovic, M.; Barrie, A.; Campbell, G.; Heinicke, S.; Humle, T.; Kouakou, C. Y.; Kühl, H. S.; Ordaz-Nemeth, I.; Pereira, H. M.; Rainer, H.; Refisch, J.; Sonter, L.; Sop, T.
10.1101/2023.10.17.562472 — ecology — Posted on 2023-10-20
1659 Enhanced local cooling effects of forests across the globe
Verbiest, W. W.; Smith, G. R.; Mirzagholi, L.; Lauber, T.; Zohner, C. M.; Maynard, D. S.; Schemm, S.; Crowther, T. W.
10.1101/2023.10.17.562656 — ecology — Posted on 2023-10-20
1661 The lung extracellular matrix protein landscape in severe early-onset and moderate chronic obstructive pulmonary disease.
Joglekar, M. M.; Bekker, N. J.; Koloko Ngassie, M. L.; Vonk, J. M.; Borghuis, T.; Reinders-Luinge, M. A.; Bakker, J.; Woldhuis, R. R.; Pouwels, S. D.; Melgert, B. N.; Timens, W.; Brandsma, C.-A.; Burgess, J. K.
10.1101/2023.10.20.562391 — molecular biology — Posted on 2023-10-20
1662 Active Suppression of the Nigrostriatal Pathway during Optogenetic Stimulation Revealed by Simultaneous fPET/fMRI
Haas, S.; Bravo, F.; Ionescu, T. M.; Gonzalez-Menendez, I.; Quintanilla-Martinez, L.; Dunkel, G.; Kuebler, L.; Hahn, A.; Lanzenberger, R.; Weigelin, B.; Reischl, G.; Pichler, B. J.; Herfert, K.
10.1101/2023.10.19.556049 — neuroscience — Posted on 2023-10-20
1669 Active microrheology with a single, time-shared laser trap
Catala-Castro, F.; Ortiz-Vasquez, S.; Martinez-Fernandez, C.; Pezzano, F.; Garcia-Cabau, C.; Jimenez-Delgado, S.; Salvatella, X.; Ruprecht, V.; Frigeri, P. A.; Krieg, M.
10.1101/2023.10.17.562595 — biophysics — Posted on 2023-10-20
1671 Comparative transcriptomics of Hirschfeldia incana and relatives highlights differences in photosynthetic pathways
Garassino, F.; Bengoa Luoni, S. A.; Cumerlato, T.; Reyes Marquez, F.; Harbinson, J.; Aarts, M. G. M.; Nijveen, H.; Smit, S.
10.1101/2023.10.18.562717 — bioinformatics — Posted on 2023-10-20
1675 De novo generation of T-cell receptors with desired epitope-binding property by leveraging a pre-trained large language model
Yang, J.; He, B.; Zhao, Y.; Jiang, F.; Wang, Z.; Guo, Y.; Xu, Z.; Yuan, B.; Song, J.; Zhang, Q.; Yao, J.
10.1101/2023.10.18.562845 — bioinformatics — Posted on 2023-10-20
1677 Extracellular matrix sulfation in the tumor microenvironment stimulates cancer stemness and invasiveness
Kusoglu, A.; Ornek, D.; Dansik, A.; Uzun, C.; Ozkan, S. N.; Sarica, S.; Yangin, K.; Ozdinc, S.; Turan Sorhun, D.; Solcan, N.; Doganalp, E. C.; Arlov, O.; Cunningham, K.; Karaoglu, I. C.; Kizilel, S.; Solaroglu, I.; Bulutay, P.; Firat, P.; Erus, S.; Tanju, S.; Dilege, S.; Vunjak-Novakovic, G.; Tuncbag, N.; Ozturk, E.
10.1101/2023.10.17.562578 — bioengineering — Posted on 2023-10-20
1678 3D Bioprinting Using Poly(ethylene-glycol)-dimethacrylate (PEGDMA) Composite
Chang, S.-Y.; Lee, J. Z. W.; Ranganath, A. S.; Ching, T.; Hashimoto, M.
10.1101/2023.10.19.562790 — bioengineering — Posted on 2023-10-20
1679 Sub-retinal transplantation of human iPSC-derived retinal sheets: A promising approach for the treatment of macular degeneration
Barabino, A.; Mellal, K.; Hamam, R.; Polosa, A.; Griffith, M.; Bouchard, J.-F.; Kalevar, A.; Hanna, R.; Bernier, G.
10.1101/2023.10.19.562811 — bioengineering — Posted on 2023-10-20
1680 Cancer-on-a-chip model shows that the adenomatous polyposis coli mutation impairs T cell engagement and killing of cancer spheroids
Bonnet, V.; Maikranz, E.; Madec, M.; Vertti-Quintero, N.; Cuche, C.; Mastrogiovanni, M.; Alcover, A.; Di Bartolo, V.; Baroud, C.
10.1101/2023.10.17.562521 — bioengineering — Posted on 2023-10-20
1683 Skimming genomes for systematics and DNA barcodes of corals
Quattrini, A. M.; McCartin, L. J.; Easton, E. E.; Horowitz, J.; Wirshing, H. H.; Bowers, H.; Mitchell, K.; Sei, M.; McFadden, C. S.; Herrera, S.
10.1101/2023.10.17.562770 — evolutionary biology — Posted on 2023-10-20
1686 Preventing extinction in an age of species migration and planetary change
Lundgren, E. J.; Wallach, A. D.; Svenning, J.-C.; Schlaepfer, M.; Andersson, A. L. A.; Ramp, D.
10.1101/2023.10.17.562809 — ecology — Posted on 2023-10-20
1687 An "alert state" ribosome population acts as a master regulator of cytokine mediated processes
Dopler, A.; Alkan, F.; Malka, Y.; Hoefakker, K.; Isaeva, O. I.; Kerkhoff, M.; Gangaev, A.; Silva, J.; Ramalho, S.; Hoekman, L.; Altelaar, M.; van der Kammen, R.; Yewdell, J. W.; Kvistborg, P.; Faller, W. J.
10.1101/2023.10.17.562425 — immunology — Posted on 2023-10-20
1689 Single-cell Transcriptional Analysis of the Cellular Immune Response in the Oral Mucosa of Mice
Cantalupo, P.; Diacou, A.; Park, S.; Soman, V.; Chen, J.; Glenn, D.; Chandran, U.; Clark, D.
10.1101/2023.10.18.562816 — immunology — Posted on 2023-10-20
1690 Aberrant macrophage activation and failed regeneration of pulmonary epithelium promote tuberculosis progression uniquely in lung tissue
Yabaji, S. M.; Lo, M.; Lata, S.; Gavrish, I.; Tseng, A. E.; O'Connel, A. K.; Gertje, H. P.; Mazzilli, S.; Tan, S.; Thurman, C. E.; Bishai, W. R.; Crossland, N.; Kobzik, L.; Kramnik, I.
10.1101/2023.10.17.562695 — immunology — Posted on 2023-10-20
1691 The Synaptic Architecture of Layer 5 Thick Tufted Excitatory Neurons in the Visual Cortex of Mice
Bodor, A. L.; Schneider-Mizell, C. M.; Zhang, C.; Elabbady, L.; Mallen, A.; Bergeson, A.; Brittain, D.; Buchanan, J.; Bumbarger, D. J.; Dalley, R.; Gamlin, C.; Joyce, E.; Kapner, D.; Kinn, S.; Mahalingam, G.; Seshamani, S.; Suckow, S.; Takeno, M.; Torres, R.; Yin, W.; Bae, J. A.; Castro, M. A.; Dorkenwald, S.; Halageri, A.; Jia, Z.; Jordan, C.; Kemnitz, N.; Lee, K.; Li, K.; Lu, R.; Macrina, T.; Mitchell, E.; Mondal, S. S.; Mu, S.; Nehoran, B.; Popovych, S.; Silversmith, W.; Turner, N. L.; Yu, S.-c.; Wong, W.; Wu, J.; Celii, B.; Campagnola, L.; Seeman, S.; Jarsky, T.; Ren, N.; Arkhipov, A.; The
10.1101/2023.10.18.562531 — neuroscience — Posted on 2023-10-20
1693 Neuronal activity modulates the incorporation of newly translated PSD-95 into a robust structure as revealed by STED and MINFLUX
Guerth, C.-M.; do Rego Barros Fernandes Lima, M. A.; Macarron Palacios, V.; Hubrich, J.; Cereceda Delgado, A. R.; Mougios, N.; Opazo, F.; D'Este, E.
10.1101/2023.10.18.562700 — neuroscience — Posted on 2023-10-20
1697 The genetic architecture of protein interaction affinity and specificity
Bendel, A.; Faure, A.; Klein, D.; Shimada, K.; Kempf, G.; Cavadini, S.; Lehner, B.; Diss, G.
10.1101/2023.10.17.562688 — systems biology — Posted on 2023-10-20
1699 TBL38 is an atypical homogalacturonan acetylesterase with a peculiar cell wall microdomain localization in Arabidopsis seed mucilage secretory cells
Dauphin, B. G.; Ropartz, D.; Ranocha, P.; Rouffle, M.; Carton, C.; Le Ru, A.; Martinez, Y.; Fourquaux, I.; Ollivier, S.; Mac-Bear, J.; Trezel, P.; Geairon, A.; Jamet, E.; Dunand, C.; Pelloux, J.; Ralet, M.-C.; Burlat, V.
10.1101/2023.10.18.562901 — plant biology — Posted on 2023-10-20
1701 Frataxin Deficiency Drives a Shift from Mitochondrial Metabolism to Glucose Catabolism, Triggering an Inflammatory Phenotype in Microglia
Sciarretta, F.; Zaccaria, F.; Ninni, A.; Ceci, V.; Turchi, R.; Apolloni, S.; Chiurchiu, V.; Tiberi, M.; D'Ambrosi, N.; Pedretti, S.; Mitro, N.; AQUILANO, K.; Lettieri Barbato, D.; Della Valle, I.; Milani, M.
10.1101/2023.10.18.562916 — physiology — Posted on 2023-10-20
1702 Low-invasive sampling method for taxonomic for the identification of archaeological and paleontological bones by proteomics of their collagens
Fabrizi, I.; Flament, S.; Rolando, C.; Delhon, C.; Gourichon, L.; Vuillien, M.; Oueslati, T.; Auguste, P.; Bray, F.
10.1101/2023.10.18.562897 — paleontology — Posted on 2023-10-20
1703 Decoupling of the Onset of Anharmonicity between a Protein and Its Surface Water around 200 K
Zheng, L.; Liu, Z.; Huang, J.; Tan, P.; Tyagi, M.; Sakai, V. G.; Yamada, T.; O'Neill, H.; Zhang, Q.; Hong, L.
10.1101/2023.10.18.562890 — biophysics — Posted on 2023-10-20
1707 Supercharged Fluorescent Protein-Apoferritin Cocrystals for Lighting Applications
Patrian, M.; Shaukat, A.; Nieddu, M.; Banda-Vazquez, J. A.; Timonen, J. V. I.; Fuenzalida Werner, J. P.; Anaya Plaza, E.; Kostiainen, M. A.; Costa, R. D.
10.1101/2023.10.17.562704 — bioengineering — Posted on 2023-10-20
1708 Maximizing Efficiency in SedaDNA Analysis: A Novel Extract Pooling Approach
Oberreiter, V.; Gelabert, P.; Brueck, F.; Franz, S.; Zelger, E.; Szedlacsek, S.; Cheronet, O.; Tenorio Cano, F.; Exler, F.; Zagorc, B.; Karavanic, I.; Banda, M.; Gasparyan, B.; Straus, L. G.; Gonzalez Morales, M. R.; Kappelman, J.; Stahlschmidt, M.; Rattei, T.; Kraemer, S. M.; Sawyer, S.; Pinhasi, R.
10.1101/2023.10.17.562718 — genomics — Posted on 2023-10-20
1711 Rapid establishment of species barriers in plants compared to animals
Monnet, F.; Postel, Z.; Touzet, P.; Fraisse, C.; Van de Peer, Y.; Vekemans, X.; Roux, C.
10.1101/2023.10.16.562535 — evolutionary biology — Posted on 2023-10-20
1712 Ataxia-telangiectasia mutated (Atm) disruption sensitizes spatially-directed H3.3K27M/TP53 diffuse midline gliomas to radiation therapy
Mangoli, A.; Wu, S.; Liu, H. Q.; Aksu, M.; Jain, V. J.; Foreman, B. E.; Regal, J. A.; Weidenhammer, L. B.; Stewart, C. E.; Guerra Garcia, M. E.; Hocke, E.; Abramson, K.; Williams, N. T.; Luo, L.; Deland, K.; Attardi, L.; Abe, K.; Hashizume, R.; Ashley, D. M.; Becher, O. J.; Kirsch, D. G.; Gregory, S. G.; Reitman, Z. J.
10.1101/2023.10.18.562892 — cancer biology — Posted on 2023-10-20
1713 Tumor-wide RNA splicing aberrations generate immunogenic public neoantigens
Kwok, D. W.; Stevers, N. O.; Nejo, T.; Chen, L. H.; Etxeberria, I.; Jung, J.; Okada, K.; Colton Cove, M.; Lakshmanachetty, S.; Gallus, M.; Barpanda, A.; Hong, C.; Chan, G. K. L.; Wu, S. H.; Ramos, E.; Yamamichi, A.; Liu, J. Y. Z.; Watchmaker, P.; Ogino, H.; Saijo, A.; Du, A.; Grishanina, N.; Woo, J.; Diaz, A.; Chang, S. M.; Phillips, J. J.; Wiita, A.; Klebanoff, C. A.; Costello, J. F.; Okada, H.
10.1101/2023.10.19.563178 — cancer biology — Posted on 2023-10-20
1715 cMYC-mediated immune repression is reversed by inhibition of H3K9/H3K27 methylation maintenance
Dye, I.; Laing, S.; Garner, I.; Mirza, H. B.; Iyer, N.; Brady, N.; Spiliopoulou, P.; Spear, S.; Robinson, J.; Fiorentino, F.; Fuchter, M. J.; Murphy, D. J.; McNeish, I. J.; Brown, R.
10.1101/2023.10.18.562888 — cancer biology — Posted on 2023-10-20
1716 Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a male mouse model of head-and-neck cancer
Barr, J.; Walz, A.; Restaino, A. C.; Williamson, C. S.; Amit, M.; Faber, S. M.; Vichaya, E. G.; Spanos, W. C.; Dantzer, R.; Talbot, S.; Vermeer, P. D.
10.1101/2023.10.18.562990 — cancer biology — Posted on 2023-10-20
1717 Yes1-mediated Cul9 phosphorylation promotes the metabolic reprogramming in gastric cancer
Wu, Y.; Zhang, H.; Zhang, S.; Wang, M.; Wang, H.; Huang, H.; Hong, X.; Zhang, Z.; Li, Y.
10.1101/2023.10.18.562906 — cancer biology — Posted on 2023-10-20
1718 Increased stromal densities of B cells, CD103+ cells, and CD163+ M2-like macrophages associate with poor clinical outcomes in BCG treated non-muscle invasive bladder cancer
Koti, M.; Ravenscroft, B.; Yolmo, P.; Chenard, S.; Rahimi, S.; Pace, K.; Sachdeva, K.; Jamaspishvilli, T.; Ghadei, H.; Garven, A.; Tyryshkin, K.; Berman, D. M.; Jackson, C.; Siemens, D. R.
10.1101/2023.10.19.562817 — cancer biology — Posted on 2023-10-20
1719 Single cell profiling of del(5q) MDS unveils its transcriptional landscape and the impact of lenalidomide
Serrano, G.; Berastegui Zufiaurre, N.; Diaz Mazkiaran, A.; Garcia Olloqui, P.; Huerga Dominguez, S.; Alfonso Pierola, A.; Ullate Agote, A.; Ariceta Ganuza, B.; Ainciburu, M.; Vilas Zornoza, A.; San Martin Uriz, P.; Aguirre Ruiz, P.; Lamo de Espinosa, J. M.; Acha, P.; Calvete, O.; Jimenez, T.; Molero, A.; Montoro, J.; Diez Campelo, M.; Valcarcel Ferreiras, D.; Sole, F.; Ochoa Alvarez, I.; Prosper Cardoso, F.; Ezponda Itoiz, T.; Hernaez Arrazola, M.
10.1101/2023.10.19.562875 — cancer biology — Posted on 2023-10-20
1720 Chemo-senolytic therapeutic potential against angiosarcoma
Wang, X.; Chung, C. Y.-L.; Yoshioka, A.; Hashimoto, S.; Jimbo, H.; Tanizawa, H.; Ohta, S.; Fukumoto, T.; Noma, K.-i.
10.1101/2023.10.19.563192 — cancer biology — Posted on 2023-10-20
1722 Interactions between ploidy and resource availability shape clonal interference at initiation and recurrence of glioblastoma
Nowicka, Z.; Rentzeperis, F.; Beck, R.; Tagal, V.; Forero Pinto, A. M.; Scanu, E.; Veith, T.; Cole, J.; Ilter, D.; Dominguez Viqueira, W.; Teer, J. K.; Maksin, K.; Pasetto, S.; Abdalah, M. A.; Fiandaca, G.; Prabhakaran, S.; Schultz, A.; Ojwang, M.; Barnholtz-Sloan, J. S.; Joaquim, F. M.; Gomes, A. P.; Katira, P.; Andor, N.
10.1101/2023.10.17.562670 — cancer biology — Posted on 2023-10-20
1723 Biofilms and core pathogens shape the tumour microenvironment and immune phenotype in colorectal cancer
Kvich, L.; Fritz, B. G.; Zschach, H.; Terkelsen, T.; Raskov, H.; Hoest-Rasmussen, K.; Jakobsen, M. R.; Gheorghe, A. G.; Gogenur, I.; Bjarnsholt, T.
10.1101/2023.10.20.563034 — cancer biology — Posted on 2023-10-20
1725 Increased stromal densities of B cells, CD103+ cells, and CD163+ M2-like macrophages associate with poor clinical outcomes in BCG treated non-muscle invasive bladder cancer
Ravenscroft, B.; Yolmo, P.; Chenard, S.; Rahimi, S.; Pace, K.; Sachdeva, K.; Jamaspishvilli, T.; Ghadei, H.; Garven, A.; Tyryshkin, K.; Berman, D. M.; Jackson, C.; Siemens, D. R.; Koti, M.
10.1101/2023.10.19.562817 — cancer biology — Posted on 2023-10-20
1727 High Resolution Biological and Physical Sampling Reveals Expression of Domoic Acid Biosynthetic Genes at Frontal Zones
Thukral, M.; Aron, A. T.; Rabines, A. J.; Petras, D.; Preston, C. M.; Zheng, H.; Fussy, Z.; James, C.; Ussler, W.; Lucas, A. J.; Anderson, C. R.; Scholin, C. A.; Dorrestein, P. C.; Ryan, J. P.; Allen, A. E.
10.1101/2023.10.19.562961 — microbiology — Posted on 2023-10-20
1729 Lethal COVID-19 Associates With RAAS-Induced Inflammation For Multiple Organ Damage Including Mediastinal Lymph Nodes
Guarnieri, J. W.; Topper, M.; Beigel, K.; Haltoom, J. A.; Chadburn, A.; Frere, J.; An, J.; Cope, H.; Borczuk, A.; Sinha, S.; Lim, C.; Kim, J.; Park, J.; Meydan, C.; Foox, J.; Mozsary, C.; Bram, Y.; Richard, S.; Epsi, N.; Agan, B.; Chenoweth, J.; Simons, M.; Tribble, D.; Burgess, T.; Dalgard, C. L.; Heise, M. T.; Moorman, N.; Baxter, V.; Madden, E. A.; Taft-Benz, S.; Anderson, E.; Sanders, W. A.; Dickmander, R. J.; Widjaja, G. A.; Janssen, K.; Lie, T.; Murdock, D. G.; Angelin, A.; Albrecht, Y. E. S.; Olali, A.; Cen, Z.; Dybas, J. M.; Priebe, W.; Emmett, M. R.; Best, S.; Johnson, M. K.; Clark, K
10.1101/2023.10.08.561395 — immunology — Posted on 2023-10-20
1730 OMICmAge: An integrative multi-omics approach to quantify biological age with electronic medical records
Chen, Q.; Dwaraka, V. B.; Carreras-Gallo, N.; Medez, K.; Chen, Y.; Kachroo, P.; Prince, N.; Went, H.; Medez, T.; Lin, A.; Turner, L.; Moqri, M.; Chu, S. H.; Kelly, R. S.; Weiss, S. T.; Rattray, N. J.; Gladyshev, V. N.; Karlson, E.; Wheelock, C.; Mathe, E. A.; Dahlin, A.; McGeachie, M. J.; Smith, R.; Lasky-Su, J. A.
10.1101/2023.10.16.562114 — bioinformatics — Posted on 2023-10-20
1733 TBK1 is ubiquitinated by TRIM5alpha to assemble mitophagy machinery
Saha, B.; Olsvik, H.; Williams, G. L.; Oh, S.; Evjen, G.; Sjottem, E.; Mandell, M. A.
10.1101/2023.10.19.563195 — cell biology — Posted on 2023-10-20
1736 Failed reprogramming of transformed cells due to induction of apoptosis and senescence impairs tumor progression in lung cancer
Pedrosa, P.; Zang, Z.; Macias, D.; Ge, J.; Denholm, M.; Dyas, A.; Nunez-Quintela, V.; Estevez-Souto, V.; Lado-Fernandez, P.; Gonzalez, P.; Gomez, M.; Martin, J. E.; Da Silva-Alvarez, S.; Munoz-Espin, D.; Collado, M.
10.1101/2023.10.19.563086 — cell biology — Posted on 2023-10-20
1739 Loss of Grp170 results in catastrophic disruption of endoplasmic reticulum functions
Mann, M. J.; Melendez-Suchi, C.; Sukhoplyasova, M.; Flory, A. R.; Carson Irvine, M.; Iyer, A.; Vorndran, H. E.; Guerriero, C. J.; Brodsky, J. L.; Hendershot, L. M.; Buck, T.
10.1101/2023.10.19.563191 — cell biology — Posted on 2023-10-20
1741 Microbiome-Derived Prion-Like Proteins and Their Potential to Trigger Cognitive Dysfunction
Seira Curto, J.; Dominguez Martinez, A.; Sotillo Sotillo, P.; Serrat Garcia, M.; Fernandez Gallegos, M. R.; Sanchez de Groot, N.
10.1101/2023.10.19.563052 — molecular biology — Posted on 2023-10-20
1742 Listeria adhesion protein orchestrates caveolae-mediated apical junctional remodeling of epithelial barrier for L. monocytogenes translocation
Drolia, R.; Tenguria, S.; Bryant, D.; Thind, J.; Amelunke, B.; Liu, D.; Gallina, N.; Mishra, K.; Samaddar, M.; Sawale, M.; Mishra, D.; Cox, A. D.; Bhunia, A. K.
10.1101/2023.10.18.563002 — microbiology — Posted on 2023-10-20
1743 Acetylcholine Modulates the Precision of Prediction Error in the Auditory Cortex
Perez-Gonzalez, D.; Lao Rodriguez, A. B.; Aedo-Sanchez, C.; Malmierca, M. S.
10.1101/2023.08.17.553683 — neuroscience — Posted on 2023-10-20
1744 Absolute number of three populations of interneurons and all GABAergic synapses in the human hippocampus
Takacs, V.; Papp, P.; Orosz, A.; Bardoczi, Z.; Zsoldos, T.; Watanabe, M.; Magloczky, Z.; Gombas, P.; Freund, T. F.; Nyiri, G.
10.1101/2023.09.26.559559 — neuroscience — Posted on 2023-10-20
1746 Botulinum toxin intoxication requires retrograde transport and membrane translocation at the ER
Jeremy, Y. C.; Tay, F.; Bennion, R. E.; Loss, O.; Maignel, J.; Pons, L.; Foster, K.; Beard, M.; Bard, F. A.
10.1101/2023.10.17.562749 — cell biology — Posted on 2023-10-20
1748 Multi-pass, single-molecule nanopore reading of long protein strands with single-amino acid sensitivity
Motone, K.; Kontogiorgos-Heintz, D.; Wee, J.; Kurihara, K.; Yang, S.; Roote, G.; Fang, Y.; Cardozo, N.; Nivala, J.
10.1101/2023.10.19.563182 — biophysics — Posted on 2023-10-20
1753 Haplotype independence contributes to evolvability in the long-term absence of sex in a mite
Oztoprak, H.; Gao, S.; Guiglielmoni, N.; Brandt, A.; Zheng, Y.; Becker, C.; Becker, K.; Bednarski, V.; Borgschulte, L.; Burak, K. A.; Dion-Cote, A.-M.; Leonov, V.; Opherden, L.; Shimano, S.; Bast, J.
10.1101/2023.09.07.556471 — evolutionary biology — Posted on 2023-10-20
1755 A brainstem to hypothalamic arcuate nucleus GABAergic circuit drives feeding
Martinez de Morentin, P. B.; Gonzalez, J. A.; Dowsett, G. K.; Martynova, Y.; Yeo, G. S. H.; Sylantyev, S.; Heisler, L. K.
10.1101/2023.05.03.538908 — neuroscience — Posted on 2023-10-20
1759 LKB1 suppresses growth and promotes the internalization of EGFR through the PIKFYVE lipid kinase
Ferrarone, J.; Thomas, J.; Unni, A.; Zheng, Y.; Nagiec, M.; Gardner, E.; Mashadova, O.; Li, K.; Koundouros, N.; Montalbano, A.; Mustafa, M.; Cantley, L.; Blenis, J.; Sanjana, N.; Varmus, H.
10.1101/2023.10.19.563158 — cancer biology — Posted on 2023-10-20
1761 Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain coupling
Lukacs, G. L.; Soya, N.; Xu, H.; Roldan, A.; Yang, Z.; Ye, H.; Premchandar, A.; Jiang, F.; Veit, G.; Cole, S. P. C.; Kappes, J. C.; Hegedus, T.
10.1101/2023.10.19.563107 — biophysics — Posted on 2023-10-20
1763 An INDEL genomic approach to explore population diversity of phytoplankton : Bathycoccus, a case study
Devic, M.; Mariac, C.; Verge, V.; Schatt, P.; Dennu, L.; Lozano, J.-C.; Bouget, F.-Y.; Sabot, F.
10.1101/2023.02.09.527951 — ecology — Posted on 2023-10-20
1764 Biogenesis of specialized lysosomes in differentiated keratinocytes relies on close apposition with the Golgi apparatus
Mahanty, S.; Bergam, P.; Belapurkar, V.; Eluvathingal, L.; Gupta, N.; Goud, B.; Nair, D.; Raposo, G.; Gangi Setty, S. R.
10.1101/2022.12.22.521712 — cell biology — Posted on 2023-10-20
1768 Tricyclic and tetracyclic antidepressants upregulate VMAT2 activity and rescue disease-causing VMAT2 variants
Wang, X.; Marmouzi, I.; Finnie, P. S.; Stove, S. I.; Bucher, M. L.; Lipina, T. V.; Ramsey, A. J.; Miller, G. W.; Salahpour, A.
10.1101/2023.10.09.561601 — pharmacology and toxicology — Posted on 2023-10-19
1769 tRNA m1G9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10
Strassler, S. E.; Bowles, I. E.; Krishnamohan, A.; Kim, H.; Edgington, C. B.; Kuiper, E. G.; Hancock, C. J.; Comstock, L.; Jackman, J. E.; Conn, G. L.
10.1101/2023.02.01.526536 — biochemistry — Posted on 2023-10-19
1771 Social Context and Reward Sensitivity Enhance Corticostriatal Function during Experiences of Shared Rewards
Zaff, O.; Wyngaarden, J. B.; Dennison, J. B.; Sazhin, D.; Chein, J.; Alloy, L. B.; McCloskey, M.; Jarcho, J.; Smith, D. V.; Fareri, D.
10.1101/2023.10.19.562908 — neuroscience — Posted on 2023-10-19
1772 A molecularly distinct cell type in the dmPAG regulates intermale aggression behaviors in mice
Li, C.-Y.; Miao, C.; Wu, J.; Ge, Y.; Gao, P.; Yin, S.; Zhang, P.; Tian, B.; Chen, W.; Chen, X.-Q.
10.1101/2023.10.19.562724 — neuroscience — Posted on 2023-10-19
1773 Trait Reward Sensitivity Modulates Connectivity with the Temporoparietal Junction and Anterior Insula during Strategic Decision Making
Sazhin, D.; Wyngaarden, J. B.; Dennison, J. B.; Zaff, O.; Fareri, D.; McCloskey, M. S.; Alloy, L. B.; Jarcho, J. M.; Smith, D. V.
10.1101/2023.10.19.563125 — neuroscience — Posted on 2023-10-19
1775 Graph perceiver network for lung tumor and premalignant lesion stratification from histopathology
Gindra, R. H.; Zheng, Y.; Green, E. J.; Reid, M. E.; Mazzilli, S. A.; Merrick, D. T.; Burks, E. J.; Kolachalama, V. B.; Beane, J. E.
10.1101/2023.10.16.562550 — pathology — Posted on 2023-10-19
1776 Reliability of dynamic causal modelling of resting state magnetoencephalography
Jafarian, A.; Assem, M. K.; Ece Kocagoncu, E.; Lanskey, J. H.; Williams, R.; Cheng, Y.-J.; Quinn, A. J.; Pitt, J.; Raymont, V.; Lowe, S.; Lowe, S.; Singh, K. D.; Woolrich, M. W.; Nobre, A. C.; Henson, R. N.; Friston, K.; Rowe, J.
10.1101/2023.10.16.562379 — biophysics — Posted on 2023-10-19
1778 Study on the preparation of bovine milk exosomes and the stability of lyophilized powder
Ge, X.; Li, T.; Lu, L.; Han, C.; Wang, M.; Du, H.; Chen, N.; Gao, M.; Wang, N.; Qi, D.; Bai, W.; Yin, J.; Dong, F.
10.1101/2023.10.16.562624 — bioengineering — Posted on 2023-10-19
1779 Growth inhibitory factor/metallothionein-3 is a sulfane sulfur-binding protein
Shinkai, Y.; Ding, Y.; Matsui, T.; Devitt, G.; Akiyama, M.; Shen, T.-L.; Nishida, M.; Ida, T.; Akaike, T.; Mahajan, S.; Fukuto, J. M.; Shigeta, Y.; Kumagai, Y.
10.1101/2023.10.19.563042 — biochemistry — Posted on 2023-10-19
1780 Unveiling APOL1 Haplotypes: A Novel Classification Through Probe-Independent Quantitative Real-Time PCR
Dogan, M.; Watkins, C.; Ingram, H.; Moore, N. A.; Rucker, G. M.; Gower, E. G.; Eason, J. D.; Bhalla, A.; Talwar, M.; Nezakatgoo, N.; Eymard, C.; Helmick, R.; Vanatta, J. M.; Bajwa, A.; Kuscu, C.; Kuscu, C.
10.1101/2023.10.16.562539 — genetics — Posted on 2023-10-19
1781 Comparative Interactome Analysis of α-arrestin Families in Human and Drosophila
Lee, K.-T.; Pranoto, I. K.; Kim, S.-Y.; Choi, H.-J.; To, N. B.; Chae, H.; Lee, J.-Y.; Kim, J.-E.; Kwon, Y. V.; Nam, J.-W.
10.1101/2023.06.11.544486 — cell biology — Posted on 2023-10-19
1782 Circadian oscillation of perireceptor events influence olfactory sensitivity in diurnal and nocturnal mosquitoes
De, T. D.; Pelletier, J.; Gupta, S.; Kona, M. P.; Singh, O. P.; Dixit, R.; Ignell, R.; Karmodiya, K.
10.1101/2023.10.19.563057 — molecular biology — Posted on 2023-10-19
1784 Colon cancer and cell transformation by clinical Salmonella strains are associated with bacterial virulence and intracellular fitness
Stevenin, V.; Coipan, C. E.; Duijster, J. W.; van Elsland, D. M.; Voogd, L.; van Hoek, A. H. A. M.; Wijnands, L. M.; Janssen, L. J.; Akkermans, J. J. L. L.; Neefjes-Borst, A.; Franz, E.; Gras, L. M.; Neefjes, J.
10.1101/2023.10.19.562874 — microbiology — Posted on 2023-10-19
1785 Temperature effects on the magnitude of the bovine ex vivo immune response towards Mycoplasmopsis bovis
Demoulins, T.; Yimthin, T.; Lindtke, D.; Eggerschwiler, L.; Siegenthaler, R.; Labroussaa, F.; Jores, J.
10.1101/2023.10.16.562468 — immunology — Posted on 2023-10-19
1787 Pan-cancer analysis reveals multifaceted roles of retrotransposon-fusion RNAs
Lee, B.; Park, J.; Voshall, A.; Maury, E.; Kang, Y.; Kim, Y. J.; Lee, J.-Y.; Shim, H.-R.; Kim, H.-J.; Lee, J.-W.; Jung, M.-H.; Kim, S.-C.; Chu, H. B. K.; Kim, D.-W.; Kim, M.; Choi, E.-J.; Hwang, O. K.; Lee, H. W.; Ha, K.; Choi, J. K.; Kim, Y.; Choi, Y.; Park, W.-Y.; Lee, E. A.
10.1101/2023.10.16.562422 — cancer biology — Posted on 2023-10-19
1788 Detection of EGFR and its Activity State in Plasma CD63-EVs from Glioblastoma Patients: Rapid Profiling using an Anion Exchange Membrane Sensor
Maniya, N.; Kumar, S.; Franklin, J. L.; Higginbotham, J. N.; Scott, A. M.; Gan, H. K.; Coffey, R. J.; Senapati, S.; Chang, H.-C.
10.1101/2023.10.16.562628 — cancer biology — Posted on 2023-10-19
1789 Functional Tissue Units in the Human Reference Atlas.
Bidanta, S.; Borner, K.; Herr, B. W.; Nagy, M.; Gustilo, K. S.; Bajema, R.; Maier, L.; Molontay, R.; Weber, G.
10.1101/2023.10.16.562593 — bioinformatics — Posted on 2023-10-19
1790 Multi-scale tissue fluorescence mapping with fibre optic ultraviolet excitation and generative modelling
Ang, J. L. Y.; Tan, K. H.; Yong, A. S. K.; Tan, C. W. X.; Kng, J. S. J.; Tan, C. J. J.; Soh, R. H. K.; Tan, J. Y. H.; Liang, K.
10.1101/2022.12.28.521919 — bioengineering — Posted on 2023-10-19
1792 Biological and genomic resources for the cosmopolitan phytoplankton Bathycoccus: Insights into genetic diversity and major structural variations
Dennu, L.; Devic, M.; Rigonato, J.; Falciatore, A.; Lozano, J.-C.; Verge, V.; Mariac, C.; Jaillon, O.; The Dark Edge genomics sampling team, ; Sabot, F.; Bouget, F.-Y.
10.1101/2023.10.16.562038 — genomics — Posted on 2023-10-19
1798 Integrin-like adhesin CglD confers traction and stabilizes bacterial focal adhesions involved in myxobacterial gliding motility
Jolivet, N. Y.; Han, E.; Belgrave, A. M.; Saïdi, F.; Koushki, N.; Lemon, D. J.; Faure, L. M.; Fleuchot, B.; Mahanta, U.; Jiang, H.; Sharma, G.; Fiche, J.-B.; Bratton, B. P.; Diallo, M.; Nan, B.; Zusman, D. R.; Sudre, G.; Garza, A.; Nollmann, M.; Ehrlicher, A. J.; Theodoly, O.; Shaevitz, J. W.; Mignot, T.; Islam, S. T.
10.1101/2023.10.19.562135 — microbiology — Posted on 2023-10-19
1799 The Leptospira HemKR two-component system regulates heme/iron homeostasis by sensing 5-aminolevulinic acid
Imelio, J. A.; Trajtenberg, F.; Zarantonelli, L.; Vitrenko, I.; Lemee, L.; Cokelaer, T.; Picardeau, M.; Buschiazzo, A.
10.1101/2023.10.19.563136 — microbiology — Posted on 2023-10-19
1800 Microtubule inner proteins of Plasmodium are essential for transmission of malaria parasites
Hentzschel, F.; Binder, A. M.; Dorner, L. P.; Herzel, L.; Nuglish, F.; Sema, M.; Aguirre-Botero, M. C.; Cyrklaff, M.; Funaya, C.; Frischknecht, F.
10.1101/2023.10.19.562943 — microbiology — Posted on 2023-10-19
1801 Effective biotechnology for reducing N2O-emissions from farmland: N2O-respiring bacteria vectored by organic waste
Hiis, E. G.; Vick, S. H. W.; Molstad, L.; Rosdal, K.; Jonassen, K. R.; Winiwarter, W.; Bakken, L. R.
10.1101/2023.10.19.563143 — microbiology — Posted on 2023-10-19
1802 Emotional Vocalizations Alter Behaviors and Neurochemical Release into the Amygdala
Ghasemahmad, Z.; Mrvelj, A.; Panditi, R.; Sharma, B.; Perumal, K. D.; Wenstrup, J. J.
10.1101/2022.07.02.498564 — neuroscience — Posted on 2023-10-19
1804 A three-node Turing gene circuit forms periodic spatial patterns in bacteria
Tica, J.; Oliver Huidobro, M.; Zhu, T.; Wachter, G. K. A.; H. Pazuki, R.; Tonello, E.; Siebert, H.; Stumpf, M. P. H.; Endres, R. G.; Isalan, M.
10.1101/2023.10.19.563112 — synthetic biology — Posted on 2023-10-19
1806 Glucocorticoid intermittence coordinates rescue of energy and mass in aging-related sarcopenia through the myocyte-autonomous PGC1alpha-Lipin1 transactivation
Prabakaran, A. D.; McFarland, K.; Miz, K.; Durumutla, H. B.; Soussi, F. E. A.; Piczer, K.; Latimer, H.; Werbrich, C.; Blair, N. S.; Millay, D. P.; Prideaux, B.; Finck, B. N.; Quattrocelli, M.
10.1101/2023.10.16.562573 — physiology — Posted on 2023-10-19
1807 Fecal microbial transfer and complex carbohydrates mediate protection against COPD
Budden, K. F.; Shukla, S.; Bowerman, K. L.; Gellatly, S. L.; Wood, D. L. A.; Lachner, N.; Idrees, S.; Patel, V.; Faiz, A. F.; Rehman, S. F.; Donovan, C.; Alemao, C.; Shen, S.; Vanka, K. S.; Mason, J.; Haw, T. J.; Fricker, M.; Keely, S.; Hansbro, N. G.; Belz, G.; Horvat, J. C.; Ashhurst, T. M.; van Vreden, C.; Mcguire, H.; Fazekas de St Groth, B. F.; King, N. J. C.; Crossett, B.; Cordwell, S. J.; Bonaguro, L.; Schultze, J. L.; Forster, S. C.; Cooper, M. A.; Segal, L.; Vaughan, A.; Collins, P.; Bowman, R.; Fong, K.; Yang, I.; Wark, P. A.; Dennis, P. G.; Hugenholtz, P.; Hansbro, P. M.
10.1101/2023.10.16.562613 — physiology — Posted on 2023-10-19
1810 Mapping ovarian cancer spatial organization uncovers immune evasion drivers at the genetic, cellular, and tissue level
Yeh, C. Y.; Aguirre, K.; Laveroni, O.; Kim, S.; Wang, A.; Liang, B.; Zhang, X.; Han, L. M.; Valbuena, R.; Plevritis, S. K.; Bassik, M. C.; Snyder, M. P.; Howitt, B. E.; Jerby, L.
10.1101/2023.10.16.562592 — cancer biology — Posted on 2023-10-19
1811 TMPyP binding evokes a complex, tunable nanomechanical response in DNA
Kretzer, B.; Herenyi, L.; Csik, G.; Supala, E.; Orosz, A.; Tordai, H.; Kiss, B.; Kellermayer, M.
10.1101/2023.10.16.562642 — biophysics — Posted on 2023-10-19
1812 Tracking live-cell single-molecule dynamics enables measurements of heterochromatin-associated protein-protein interactions
Chen, Z.; Seman, M.; Farhat, A.; Fyodorova, Y.; Biswas, S.; Levashkevich, A.; Freddolino, L. P.; Biteen, J. S.; Ragunathan, K.
10.1101/2023.03.08.531771 — biophysics — Posted on 2023-10-19
1815 Neuroinflammation increases oxygen extraction in a mouse model of Alzheimer's disease
Liu, C.; Cardenas-Rivera, A.; Teitelbaum, S.; Birmingham, A.; Alfadhel, M.; Yaseen, M. A.
10.1101/2023.10.16.562353 — bioengineering — Posted on 2023-10-19
1816 Quantifying and mitigating recorder-induced variability in ecological acoustic indices
Luna-Naranjo, D.; Martinez, J. D.; Sanchez-Giraldo, C.; Daza, J. M.; Lopez, J. D.
10.1101/2023.10.16.562620 — bioengineering — Posted on 2023-10-19
1817 A peptide-centric local stability assay to unveil protein targets of diverse ligands
Li, K.; Chen, S.; Wang, K.; Wang, Y.; Fang, Z.; Lyu, J.; Zhu, H.; Li, Y.; Yu, T.; Yang, F.; Zhang, X.; Guo, S.; Ruan, C.; Zhou, J.; Wang, Q.; Luo, C.; Ye, M.
10.1101/2023.10.17.562693 — biochemistry — Posted on 2023-10-19
1818 Distinct function of Chlamydomonas CTRA-CTR transporters in Cu assimilation and intracellular mobilization
Strenkert, D.; Schmollinger, S.; Paruthiyil, S.; Brown, B. C.; Green, S.; Shafer, C. M.; Salome, P. A.; Nelson, H.; Blaby-Haas, C. E.; Moseley, J. L.; Merchant, S. S.
10.1101/2023.10.19.563170 — biochemistry — Posted on 2023-10-19
1822 Di- and tri-methylation of histone H3K36 play distinct roles in DNA double-strand break repair
Chen, R.; Zhao, M.-J.; Li, Y.-M.; Liu, A.-H.; Wang, R.-X.; Mei, Y.-C.; Chen, X.; Du, H.-N.
10.1101/2023.10.18.562911 — biochemistry — Posted on 2023-10-19
1823 A BAC-guided haplotype assembly pipeline increases the resolution of the virus resistance locus CMD2 in cassava
Cornet, L.; Zaidi, S. S.-e.-A.; Li, J.; ngapout, Y.; Shakir, S.; Meunier, L.; callot, C.; marande, w.; Hanikenne, M.; Rombauts, S.; Van De Peer, Y.; Vanderschuren, H.
10.1101/2023.10.19.563145 — genomics — Posted on 2023-10-19
1825 Flap endonuclease 1 repairs DNA-protein crosslinks via ADP-ribosylation
Sun, Y.; Jenkins, L. M.; El Touny, L. H.; Jo, U.; Yang, X.; Maity, T. K.; Uribe, I.; Saha, S.; Takeda, S.; Leung, A. K. L.; Cheng, K.; Pommier, Y.
10.1101/2023.10.19.563118 — molecular biology — Posted on 2023-10-19
1826 FVIII interacts with cell surface to regulate endothelial cell functionality
Olgasi, C.; Cucci, A.; Molineris, I.; Assanelli, S.; Anselmi, F.; Borsotti, C.; Sgromo, C.; Lauria, A.; Merlin, S.; Walker, G.; Capasso, P.; Oliviero, S.; Follenzi, A.
10.1101/2023.10.19.563105 — molecular biology — Posted on 2023-10-19
1827 HDL regulates TGFβ-receptor lipid raft partitioning, restoring contractile features of cholesterol-loaded vascular smooth muscle cells
Thevkar Nagesh, P.; Nishi, H.; Rawal, S.; Zahir, T.; Miano, J. M.; Sorci-Thomas, M.; Xu, H.; Akbar, N.; Choudhury, R. P.; Misra, A.; Fisher, E.
10.1101/2023.10.19.562786 — molecular biology — Posted on 2023-10-19
1828 Exploring archaeogenetic studies of dental calculus to shed light on past human migrations in Oceania
Velsko, I. M.; Fagernas, Z.; Tromp, M.; Bedford, S.; Buckley, H.; Clark, G.; Dudgeon, J.; Flexner, J. L.; Leal-Tamarii, A.; Lewis, C.; Lisa, M.-S.; Nagele, K.; Ozga, A.; Rohrlach, A. B.; Posth, C.; Shing, R.; Spriggs, M.; Willie, E.; Valentin, F.; Warinner, C.
10.1101/2023.10.18.563027 — microbiology — Posted on 2023-10-19
1829 Diurnal rhythmicity of fecal microbiota and metabolite profiles in the first year of life: a randomized controlled interventional trial with infant formula
Heppner, N.; Reitmeier, S.; Heddes, M.; Vig Merino, M.; Schwartz, L.; Dietrich, A.; List, M.; Gigl, M.; Meng, C.; Omer, H.; Kleigrewe, K.; Schirmer, M.; Kiessling, S.; Haller, D.
10.1101/2023.10.19.563092 — microbiology — Posted on 2023-10-19
1831 The panC-encoded pantothenate synthetase to tackle carbapenem-resistant OprD Pseudomonas aeruginosa mutant revealed through Tn-Seq
Van Maele, C.; Caboche, S.; Moutel, M.; Bonnomet, A.; Moussalih, S.; Luczka, E.; Jacquier, H.; Muggeo, A.; Guillard, T.
10.1101/2023.10.19.563089 — microbiology — Posted on 2023-10-19
1832 Immune landscape of tertiary lymphoid structures in hepatocellular carcinoma (HCC) treated with neoadjuvant immune checkpoint blockade
Shu, D. H.; Ho, W. J.; Kagohara, L. T.; Girgis, A.; Shin, S. M.; Danilova, L.; Lee, J. W.; Sidiropoulos, D. N.; Mitchell, S.; Munjal, K.; Howe, K.; Bendinelli, K. J.; Qi, H.; Mo, G.; Montagne, J.; Leatherman, J. M.; Lopez-Vidal, T. Y.; Zhu, Q.; Huff, A. L.; Yuan, X.; Hernandez, A.; Coyne, E. M.; Zaidi, N.; Zabransky, D. J.; Engle, L. L.; Ogurtsova, A.; Baretti, M.; Laheru, D.; Durham, J. N.; Wang, H.; Anders, R.; Jaffee, E. M.; Fertig, E. J.; Yarchoan, M.
10.1101/2023.10.16.562104 — immunology — Posted on 2023-10-19
1834 The genetic evolution of acral melanoma
Wang, M.; Fukushima, S.; Sheen, Y.-S.; Ramelyte, E.; Cruz Pacheco, N.; Shi, C.; Liu, S.; Banik, I.; Aquino, J. D.; Sangueza Acosta, M.; Levesque, M.; Dummer, R.; Liau, J.-Y.; Chu, C.-Y.; Shain, A. H.; Yeh, I.; Bastian, B. C.
10.1101/2023.10.18.562802 — cancer biology — Posted on 2023-10-19
1836 TARO: tree-aggregated factor regression for microbiome data integration
Mishra, A. K.; Mahmud, I.; Lorenz, P. L.; Jenq, R. K.; Wargo, J.; Ajami, N. J.; Peterson, C. B.
10.1101/2023.10.17.562792 — bioinformatics — Posted on 2023-10-19
1837 A novel approach to identify cross-identity peptides between Epstein-Barr virus and central nervous system proteins in Guillain-Barre syndrome and multiple sclerosis
Patrocinio, H. K. M.; Fiuza, T. S.; Oliveira, J. I. N.; Rodrigues-Neto, J. F.; Jeronimo, S. M. B.; de Souza, G. A.; Lima, J. P. M. S.
10.1101/2023.10.17.562729 — bioinformatics — Posted on 2023-10-19
1839 Local structural flexibility drives oligomorphism in computationally designed protein assemblies
Khmelinskaia, A.; Bethel, N. P.; Fatehi, F.; Antanasijevic, A.; Borst, A. J.; Lai, S.-H.; Wang, J. Y.; Basu Mallik, B.; Miranda, M. M.; Watkins, A. M.; Ogohara, C.; Caldwell, S.; Wu, M.; Heck, A. J. R.; Veesler, D.; Baker, D.; Twarock, R.; King, N. P.
10.1101/2023.10.18.562842 — bioengineering — Posted on 2023-10-19
1841 Evolution of microRNAs in Amoebozoa and implications for the origin of multicellularity
Edelbroek, B.; Kjellin, J.; Biryukova, I.; Liao, Z.; Lundberg, T.; Noegel, A. A.; Eichinger, L.; Friedlander, M. R.; Soderbom, F.
10.1101/2023.10.19.562841 — evolutionary biology — Posted on 2023-10-19
1843 Niche Availability and Competitive Facilitation Control Proliferation of Bacterial Strains Intended for Soil Microbiome Interventions
Causevic, S.; Dubey, M.; Morales, M.; Salazar, G. G.; Sentchilo, V.; Carraro, N.; Ruscheweyh, H.-J.; Sunagawa, S.; van der Meer, J. R.
10.1101/2023.10.17.562719 — ecology — Posted on 2023-10-19
1844 AnophelesModel: An R package to interface mosquito bionomics, human exposure and intervention effects with models of malaria intervention impact
Golumbeanu, M.; Briët, O.; Champagne, C.; Lemant, J.; Winkel, M.; Zogo, B.; Gerhards, M.; Sinka, M.; Chitnis, N.; Penny, M.; Pothin, E.; Smith, T.
10.1101/2023.10.17.562838 — ecology — Posted on 2023-10-19
1845 The human cytomegalovirus-encoded pUS28 antagonizes CD4+ T-cell recognition by targeting CIITA
Maassen, F.; Le-Trilling, V. T. K.; Betke, L.; Bracht, T.; Schuler, C.; Bayer, M.; Belter, A.; Becker, T.; Katschinski, B.; Frappier, L.; Sitek, B.; Fleischhauer, K.; Trilling, M.
10.1101/2023.10.17.562683 — immunology — Posted on 2023-10-19
1849 A novel approach to exploring the dark genome and its application to mapping of the vertebrate virus 'fossil record'.
Blanco-Melo, D.; Campbell, M. A.; Zhu, H.; Dennis, T.; Mohda, S.; Lytras, S.; Hughes, J. J.; Gatseva, A.; Gifford, R. J.
10.1101/2023.10.17.562709 — genomics — Posted on 2023-10-19
1852 Th2 and Th17-Associated Immunopathology Following SARS-CoV-2 Breakthrough Infection in Spike-vaccinated ACE2-humanized Mice
Zhang, T.; Magazine, N.; McGee, M. C.; Carossino, M.; Veggiani, G.; Kousoulas, K. G.; August, A.; Huang, W.
10.1101/2023.10.18.563016 — immunology — Posted on 2023-10-19
1853 Spatially specific, closed-loop infrared thalamocortical deep brain stimulation
Coventry, B. S.; Lawlor, G. L.; Bagnati, C. B.; Krogmeier, C.; Bartlett, E. L.
10.1101/2023.10.04.560859 — neuroscience — Posted on 2023-10-19
1855 Insulin Receptor Loss Impairs Mammary Tumorigenesis in Mice
Podmore, L. M.; Poloz, Y.; Iorio, C.; Mouaaz, S.; Nixon, K.; Smirnov, P.; McDonnell, B.; Lam, S.; Zhang, B.; Tharmapalan, P.; Sarkar, S.; Vyas, F.; Ennis, M.; Dowling, R.; Stambolic, V.
10.1101/2022.05.06.490906 — cancer biology — Posted on 2023-10-19
1856 Mechanical coupling with the nuclear envelope shapes the S. pombe mitotic spindle
Begley, M. A.; Pagan Medina, C.; Couture, T.; Zareiesfandabadi, P.; Rapp, M. B.; Tirfe, M.; LeBlanc, S.; Betterton, M. D.; Elting, M. W.
10.1101/2022.12.28.522145 — biophysics — Posted on 2023-10-19
1865 Inoviridae prophage and host dynamics during diversification, succession and Atlantic invasion of Pacific-native Vibrio parahaemolyticus.
Foxall, R. L.; Means, J.; Marcinkiewicz, A.; Schillaci, C.; DeRosia-Banick, K.; Xu, F.; Hall, J. A.; Jones, S. H.; Cooper, V. S.; Whistler, C. A.
10.1101/2023.03.23.534014 — microbiology — Posted on 2023-10-19
1866 ISG15/USP18/STAT2 is a molecular hub regulating autocrine IFN I-mediated control of Dengue and Zika virus replication
Espada, C. E.; da Rocha, E. L.; Ricciardi-Jorge, T.; dos Santos, A. A.; Soares, Z. G.; Malaquias, G.; Patricio, D. d. O.; Kozlova, E. G.; dos Santos, P. F.; Bordignon, J.; Sanford, T. J.; Fajardo, T.; Sweeney, T.; Bafica, A.; Mansur, D. S.
10.1101/784678 — immunology — Posted on 2023-10-19
1872 Heterogeneity of Tethered Agonist Signaling in Adhesion G Protein-Coupled Receptors
Dates, A. N.; Jones, D. T. D.; Smith, J. S.; Skiba, M. A.; Rich, M. F.; Burruss, M. M.; Kruse, A. C.; Blacklow, S. C.
10.1101/2022.07.14.500097 — biochemistry — Posted on 2023-10-19
1873 Proximity proteomics reveals UCH-L1 as an NLRP3 interactor that modulates IL-1β production in human macrophages and microglia
Liang, Z.; Damianou, A.; Vendrell, I.; Jenkins, E.; Lassen, F. H.; Washer, S. J.; Liu, G.; Yi, G.; Lou, H.; Cao, F.; Zheng, X.; Fernandes, R.; Dong, T.; Tate, E. W.; Daniel, E. D.; Kessler, B. M.
10.1101/2023.10.09.561576 — biochemistry — Posted on 2023-10-19
1874 Major axes of variation in tree demography across global forests
Leite, M. d. S.; McMahon, S. M.; Prado, P. I.; Davies, S. J.; Oliveira, A. A. d.; De Deurwaerder, H. P.; Aguilar, S.; Anderson-Teixeira, K. J.; Aqilah, N.; Bourg, N. A.; Brockelman, W. Y.; Castano, N.; Chang-Yang, C.-H.; Chen, Y.-Y.; Chuyong, G.; Clay, K.; Duque, A.; Ediriweera, S.; Ewango, C. E. N.; Gilbert, G.; Gunatilleke, I. A. U. N.; Gunatilleke, C. V. S.; Howe, R.; Huasco, W. H.; Itoh, A.; Johnson, D. J.; Kenfack, D.; Kral, K.; Leong, Y. T.; Lutz, J. A.; Makana, J.-R.; Malhi, Y.; McShea, W. J.; Mohamad, M.; Nasardin, M.; Nathalang, A.; Parker, G.; Parmigiani, R.; Perez, R.; Phillips, R.
10.1101/2023.01.11.523538 — ecology — Posted on 2023-10-19
1875 Consistent individual positions within roosts in Spix's disc-winged bats
Giacomini, G.; Chaves-Ramirez, S.; Hernandez-Pinson, A.; Barrantes, J. P.; Chaverri, G.
10.1101/2022.11.04.515223 — ecology — Posted on 2023-10-19
1876 Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis
Min, K.; Yenilmez, B.; Kelly, M.; Echeverria, D.; Elleby, M.; Lifshitz, L. M.; Raymond, N.; Tsagkaraki, E.; Harney, S. M.; DiMarzio, C.; Wang, H.; McHugh, N.; Bramato, B.; Morrison, B.; Rothstein, J. D.; Khvorova, A.; Czech, M. P.
10.1101/2023.05.03.539244 — molecular biology — Posted on 2023-10-19
1878 High-dimensional profiling demonstrates complexity, tissue imprinting, and lineage-specific precursors within the mononuclear phagocyte compartment of the human intestine
Fenton, T. M.; Wulff, L.; Jones, G.-R.; Vandamme, J.; Jorgensen, P. B.; Bain, C. C.; Lee, J.; Izarzugaza, J. M.; Belling, K. G.; Ho, G.-t.; Nielsen, O. H.; Riis, L. B.; Pers, T. H.; Jacobsen, H. L.; Mowat, A. M.; Brunak, S.; Agace, W. W.
10.1101/2021.03.28.437379 — immunology — Posted on 2023-10-19
1879 Using the E. coli Alleleome in Strain Design
Phaneuf, P. V.; Jarczynska, Z. D.; Kandasamy, V.; Chauhan, S. M.; Feist, A. M.; Palsson, B. O.
10.1101/2023.09.17.558058 — synthetic biology — Posted on 2023-10-19
1880 PenTag, a Versatile Platform for Synthesizing Protein-Polymer Biohybrid Materials
Mohsenin, H.; Pacheco, J.; Kemmer, S.; Wagner, H.; Hoefflin, N.; Bergmann, T.; Baumann, T.; Jerez-Longres, C.; Ripp, A.; Jork, N.; Jessen, H. J.; Fussenegger, M.; Koehn, M.; Timmer, J.; Weber, W.
10.1101/2023.05.18.541264 — synthetic biology — Posted on 2023-10-19
1881 Inferring condition in wild mammals: body condition indices confer no benefit over measuring body mass across ecological contexts
Wishart, A. E.; Guerrero-Chacon, A. L.; Smith, R.; Hawkshaw, D. M.; McAdam, A. G.; Dantzer, B.; Boutin, S.; Lane, J. E.
10.1101/2023.01.31.524791 — physiology — Posted on 2023-10-19
1883 A deeper cascade of mechanisms involved in cold resistance in Hevea brasiliensis
Silva, C. C.; Bajay, S. K.; Aono, A. H.; Francisco, F. R.; Junior, R. B.; de Souza, A. P.; Mantello, C. C.; Vicentini dos Santos, R.
10.1101/2021.11.02.466997 — genomics — Posted on 2023-10-19
1885 Trans-Lesion Synthesis and Mismatch Repair Pathway Crosstalk Defines Chemoresistance and Hypermutation Mechanisms in Glioblastoma
Cheng, X.; An, J.; Lou, J.; Gu, Q.; Ding, W.; Droby, G.; Wang, Y.; Wang, C.; Gao, Y.; Shelton, A.; Satterlee, A. B.; Mann, B. E.; Hsiao, Y.-C.; Liu, C.-W.; Liu, K.; Hingtgen, S.; Wang, J.; Liu, Z.; Miller, R.; Wu, D.; Vaziri, C.; Yang, Y.
10.1101/2023.10.16.562506 — cancer biology — Posted on 2023-10-19
1887 Anaplerotic nutrient stress drives synergy of angiogenesis inhibitors with therapeutics targeting tumor metabolism
Khadka, S.; Lin, Y.-H.; Ackroyd, J. J.; Chen, Y.-A.; Sheng, Y.; Qian, W.; Guo, S.; Chen, Y.; Behr, E. I.; Barekatain, Y.; Uddin, M. N.; Arthur, K.; Yan, V. C.; Chang, E.; Poral, A.; Tran, T.; Hsu, W.-H.; Chaurasiya, S.; Georgiou, D. K.; Asara, J. M.; Barthel, F. P.; Millward, S. W.; DePinho, R. A.; Muller, F. L.
10.1101/2023.05.07.539744 — cancer biology — Posted on 2023-10-19
1889 Adaptive capacity of a DNA polymerase clamp-loader ATPase complex
Subramanian, S.; Zhang, W.; Nimkar, S.; Kamel, M.; O'Donnell, M. E.; Kuriyan, J.
10.1101/2023.10.18.562948 — biochemistry — Posted on 2023-10-19
1891 Cell age, not chronological age, governs the dynamics and longevity of circulating CD4+ memory T cells
Bullock, M. E.; Hogan, T.; Morris, S.; Nowicka, M.; van Dorp, C.; Yates, A. J.; Seddon, B.
10.1101/2023.10.16.562650 — immunology — Posted on 2023-10-19
1898 Membrane Lipids Augment Cell Envelope Stress Signaling and Resistance to Antibiotics and Antimicrobial Peptides in Enterococcus faecalis
Miller, W. R.; Nguyen, A.; Singh, K. V.; Rizvi, S.; Khan, A.; Erickson, S. G.; Egge, S. L.; Cruz, M.; Dinh, A. Q.; Diaz, L.; Zhang, R.; Xu, L.; Garsin, D. A.; Shamoo, Y.; Arias, C. A.
10.1101/2023.10.17.562839 — microbiology — Posted on 2023-10-19
1903 UGGT1/2-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins
Ninagawa, S.; Matsuo, M.; Ying, D.; Aso, S.; Matsushita, K.; Fueki, A.; Saito, S.; Imami, K.; Kizuka, Y.; Sakuma, T.; Yamamoto, T.; Yagi, H.; Kato, K.; Mori, K.
10.1101/2023.10.18.562958 — cell biology — Posted on 2023-10-19
1904 Dose-dependent effects of histone methyltransferase NSD2 on site-specific double-strand break repair
IWASAKI, K.; KOBAYASHI, H.; Kamimura, Y.; Horikoshi, Y.; Fukuto, A.; Sun, J.; Yasui, M.; HONMA, M.; Okabe, A.; Fujiki, R.; Keneda, A.; Tashiro, S.; Sassa, A.; URA, K.
10.1101/2023.10.18.562991 — cell biology — Posted on 2023-10-19
1906 Analysis of NIH K99/R00 Awards and the Career Progression of Awardees
Woitowich, N. C.; Hengel, S. R.; Solis, C.; Vilgalys, T. P.; Babdor, J.; Tyrrell, D. J.
10.1101/2023.01.26.525751 — scientific communication and education — Posted on 2023-10-19
1909 Mechanism and cellular function of direct membrane binding by the ESCRT and ERES-associated Ca2+-sensor ALG-2
Shukla, S.; Chen, W.; Rao, S.; Yang, S.; Ou, C.; Larsen, K. P.; Hummer, G.; Hanson, P. I.; Hurley, J. H.
10.1101/2023.10.17.562764 — biophysics — Posted on 2023-10-19
1910 Convergent and divergent responses of the rhizosphere chemistry and bacterial communities to a stress gradient in the Atacama Desert.
Dussarrat, T.; Latorre, C.; Barros Santos, M. C.; Aguado-Norese, C.; Prigent, S.; Diaz, F. P.; Rolin, D.; Gonzalez, M.; Müller, C.; Gutierrez, R. A.; Petriacq, P.
10.1101/2023.10.16.562209 — ecology — Posted on 2023-10-19
1913 Identification of new markers of angiogenic sprouting using transcriptomics: New role for RND3
Abbey, C. A.; Duran, C. L.; Chen, Z.; Chen, Y.; Roy, S.; Coffell, A.; Chakraborty, S.; Wells, G. B.; Chang, J.; Bayless, K.
10.1101/2023.10.18.563021 — cell biology — Posted on 2023-10-19
1914 Zinc controls histone acetyltransferase KAT7 activity to maintain cellular zinc homeostasis
Fujisawa, T.; Takenaka, S.; Maekawa, L.; Kowada, T.; Matsui, T.; Mizukami, S.; Naguro, I.; Ichijo, H.
10.1101/2023.10.18.562865 — cell biology — Posted on 2023-10-19
1915 Enhancer-driven local 3D chromatin domain folding modulates transcription in human mammary tumor cells
Kocanova, S.; Raynal, F.; Goiffon, I.; Oksuz, B. A.; Bau, D.; Kamgoue, A.; Cantaloube, S.; Zhan, Y.; Lajoie, B.; Marti-Renom, M. A.; Dekker, J.; Bystricky, K.
10.1101/2023.10.17.562690 — cell biology — Posted on 2023-10-19
1916 Mitochondrial protein C15ORF48 is a stress-independent inducer of autophagy that regulates oxidative stress and autoimmunity
Takakura, Y.; Machida, M.; Terada, N.; Katsumi, Y.; Kawamura, S.; Horie, K.; Miyauchi, M.; Ishikawa, T.; Akiyama, N.; Seki, T.; Miyao, T.; Hayama, M.; Endo, R.; Ishii, H.; Maruyama, Y.; Hagiwara, N.; Kobayashi, T. J.; Yamaguchi, N.; Takano, H.; Akiyama, T.; Yamaguchi, N.
10.1101/2023.10.17.562644 — cell biology — Posted on 2023-10-19
1918 Disulfiram reduces atherosclerosis and enhances efferocytosis, autophagy, and atheroprotective gut microbiota in hyperlipidemic mice.
Traughber, C. A.; Timinski, K.; Prince, A.; Bhandari, N.; Neupane, K.; Khan, M. R.; Opoku, E.; Opoku, E.; Brubaker, G.; Nageshwar, K.; Ertugral, E. G.; Naggareddy, P.; Kothapalli, C. R.; Smith, J.; Gulshan, K.
10.1101/2023.10.17.562757 — cell biology — Posted on 2023-10-19
1920 Universal conditions for establish continuous cell cultures in ray-finned fishes
Cardoso, A. L.; Nascimento-Oliveira, J. I.; Climaco, J. P. S.; Venturelli, N. B.; Moreira, C. d. N.; Martins, C.
10.1101/2023.10.17.562716 — cell biology — Posted on 2023-10-19
1921 TFEB degradation is regulated by an IKK/β-TrCP2 phosphorylation-ubiquitination cascade
Xiong, Y.; Sharma, J.; Young, M. N.; Xiong, W.; Jazayeri, A.; Poncha, K. F.; Ilagan, M. X.; Wang, Q.; Zheng, H.; Young, N. L.; Sardiello, M.
10.1101/2023.10.16.562572 — cell biology — Posted on 2023-10-19
1924 Genome dilution by cell growth drives starvation-like proteome remodeling in mammalian and yeast cells
Lanz, M. C.; Zhang, S.; Swaffer, M. P.; Hernandez-Götz, L.; McCarty, F.; Ziv-Uziel, I.; Jarosz, D. F.; Elias, J. E.; Skotheim, J. M.
10.1101/2023.10.16.562558 — cell biology — Posted on 2023-10-19
1926 c-Maf and Mafb function combinatorially to establish SGN subtype-specific synaptic properties
Bastille, I.; Lee, L.; Moncada-Reid, C.; Yu, W.-M.; Sitko, A.; Yung, A.; Goodrich, L.
10.1101/2023.10.18.562788 — neuroscience — Posted on 2023-10-19
1928 Angiopoietin-like protein 2 mediates vasculopathy driven fibrogenesis in a mouse model of systemic sclerosis
Saha, D.; Thannimangalath, S.; Pincha, N.; Kiran, R.; Hegde, A.; Kataria, S.; Dam, B.; Hiwale, A.; Ravula, V.; Rahulan, L. M.; Nigam, N.; Singh, N.; Agarwal, V.; Vemula, P. K.; Jamora, C.
10.1101/2023.10.16.562467 — pathology — Posted on 2023-10-19
1929 Multicolor on-chip fluorescence microscopy for real-time surgical guidance
Roschelle, M. L.; Rabbani, R.; Papageorgiou, E.; Zhang, H.; Cooperberg, M.; Stohr, B. A.; Niknejad, A.; Anwar, M.
10.1101/2023.10.16.562247 — cancer biology — Posted on 2023-10-19
1932 Unveiling the A-to-I mRNA editing machinery and its regulation and evolution in fungi
Feng, C.; Xin, K.; Du, Y.; Zou, J.; Xing, X.; Xiu, Q.; Zhang, Y.; Zhang, R.; Huang, W.; Wang, Q.; Jiang, C.; Wang, X.; Kang, Z.; Xu, J.-R.; Liu, H.
10.1101/2023.10.18.562923 — molecular biology — Posted on 2023-10-19
1933 Targeting CD45 by gene-edited CAR-T cells for leukemia eradication and hematopoietic stem cell transplantation preconditioning
Stepanova, V. M.; Volkov, D. V.; Osipova, D. S.; Wang, W.; Hou, Y.; Pershin, D. E.; Fadeeva, M. S.; Malahova, E. A.; Kulakovskaya, E. A.; Cuicui, L.; Zhao, M.; Zhang, H.; Xie, J.; Zhang, D.; Mamedov, I. Z.; Chernov, A. S.; Telegin, G. B.; Rubtsov, Y. P.; Gabibov, A. G.; Maschan, M. A.; Wu, P.; Stepanov, A. V.
10.1101/2023.10.18.562763 — molecular biology — Posted on 2023-10-19
1935 XIST dampens X chromosome activity in a SPEN-dependent manner during early human development
Alfeghaly, C.; Castel, G.; Cazottes, E.; Moscatelli, M.; Moinard, E.; Casanova, M.; Boni, J.; Mahadik, K.; Lammers, J.; Freour, T.; Chauviere, L.; Piqueras, C.; Boers, R.; Boers, J.; Gribnau, J.; David, L.; Ouimette, J.-F.; Rougeulle, C.
10.1101/2023.10.19.563078 — molecular biology — Posted on 2023-10-19
1936 Membrane Lipids Augment Cell Envelope Stress Signaling and Resistance to Antibiotics and Antimicrobial Peptides in Enterococcus faecalis
Miller, W. R.; Nguyen, A.; Singh, K. V.; Rizvi, S.; Khan, A.; Erickson, S. G.; Egge, S. L.; Cruz, M.; Dinh, A. Q.; Diaz, L.; Zhang, R.; Xu, L.; Garsin, D. A.; Shamoo, Y.; Arias, C. A.
10.1101/2023.10.17.562839 — microbiology — Posted on 2023-10-19
1940 A 2-Hydroxybutyrate-mediated feedback loop regulates muscular fatigue
Wadsworth, B. J.; Leiwe, M.; Minogue, E.; Cunha, P. P.; Engman, V.; Brombach, C.; Asvestis, C.; Sah-Teli, S. K.; Marklund, E.; Karppinen, P.; Ruas, J. L.; Rundqvist, H.; Lanner, J.; Johnson, R. S.
10.1101/2023.10.16.562554 — physiology — Posted on 2023-10-19
1941 ACSL4 activity drives TNBC metastasis by positively regulating Histone H3 Acetylation mediated SNAIL expression
Sinha, A.; Saini, K. K.; Tripathi, K.; Khan, M. A.; Satrusal, S. R.; Verma, A.; Mandal, B.; Rai, P.; Meena, S.; NENGROO, M. A.; Singh, M. P.; Bhushan, N. S.; Vasudevan, M.; Singhai, A.; Singh, K.; Mishra, A. K.; Datta, D.
10.1101/2023.10.16.562466 — cancer biology — Posted on 2023-10-19
1943 Chronically disrupted sleep induces senescence in the visceral adipose tissue of C57BL/6J mice
Timonina, D.; Hormazabal, G. V.; Heckenbach, I.; Anderton, E.; Haky, L.; Floro, A.; Riley, R.; Kwok, R.; Breslin, S.; Ingle, H.; Tiwari, R.; Bielska, O.; Scheibye-Knudsen, M.; Kasler, H. G.; Campisi, J.; Walter, M.; Verdin, E.
10.1101/2023.10.17.562803 — molecular biology — Posted on 2023-10-19
1944 Adenine methylation is very scarce in the drosophila genome and not erased by the Ten Eleven Translocation dioxygenase.
Boulet, M.; Gilbert, G.; Renaud, Y.; Schmidt-Dengler, M.; Plantie, E.; Bertrand, R.; Nan, X.; Jurkowski, T.; Helm, M.; Vandel, L.; Waltzer, L.
10.1101/2023.09.15.557947 — molecular biology — Posted on 2023-10-19
1946 Guanine quadruplexes mediate mitochondrial RNA polymerase pausing
Snyder, R.; Delker, D.; Burdick, J. T.; Cheung, V. G.; Watts, J. A.
10.1101/2023.10.17.562821 — molecular biology — Posted on 2023-10-19
1948 Stress-induced nucleoid remodeling in Deinococcus radiodurans is associated with major changes in HU abundance and dynamics
Vauclare, P.; Wulffele, J.; Lacroix, F.; Servant, P.; Confalonieri, F.; Kleman, J.-P.; Bourgeois, D.; TIMMINS, J.
10.1101/2023.10.18.562934 — microbiology — Posted on 2023-10-19
1949 FLI1 localization to the chlamydial inclusion involves multiple mechanisms
Sturd, N. A.; Olson-Wood, M. G.; Durham, L.; Ouellette, S. P.; Rucks, E. A.
10.1101/2023.10.17.562819 — microbiology — Posted on 2023-10-19
1950 THE DUAL ROLE OF THE MICROCYSTIS AERUGINOSA MICROBIOME ON CYANOTOXIN PRODUCTION: COMPETITION FOR AND REMINERALIZATION OF ORGANIC NITROGEN
Li, W.; Baliu-Rodriguez, D.; Premathilaka, S. H.; Thenuwara, S. I.; Kimbrel, J. A.; Samo, T. J.; Ramon, C.; Kiledal, E. A.; Rivera, S. R.; Kharbush, J.; Weber, P.; Dick, G. J.; Isailovic, D.; Mayali, X.
10.1101/2023.10.18.562967 — microbiology — Posted on 2023-10-19
1951 The Aspergillus fumigatus maiA gene contributes to cell wall homeostasis and fungal virulence.
Guruceaga, X.; Perez-Cuesta, U.; Martin-Vicente, A.; Pelegri-Martinez, E.; Thorn, H. I.; Cendon-Sanchez, S.; Xie, J.; Nywening, A.; Ramirez-Garcia, A.; Fortwendel, J. R.; Rementeria, A.
10.1101/2023.10.18.562787 — microbiology — Posted on 2023-10-19
1955 Defining metabolic flexibility in hair follicle stem cell induced squamous cell carcinoma
Galvan, C.; Flores, A.; Cerillos, V.; Avila, I.; Murphy, C.; Zheng, W.; To, T. T.; Christofk, H.; Lowry, W.
10.1101/2023.10.16.562128 — cancer biology — Posted on 2023-10-19
1956 Membrane Mimetic-Dependence of GPCR Energy Landscapes
Thakur, N.; Ray, A.; Lyman, E.; Gao, Z.; Jacobson, K. A.; Eddy, M. T.
10.1101/2023.10.16.562552 — biophysics — Posted on 2023-10-19
1959 Nucleosome reorganisation in breast cancer tissues
Jacob, D. R.; Guiblet, W. M.; Mamayusupova, H.; Shtumpf, M.; Ciuta, I.; Ruje, L.; Gretton, S.; Bikova, M.; Correa, C.; Dellow, E.; Agrawal, S. P.; Shafiei, N.; Drobysevskaja, A.; Armstrong, C. M.; Lam, J. D. G.; Vainshtein, Y.; Clarkson, C. T.; Thorn, G. J.; Sohn, K.; Madapura, P. B.; Chandrasekharan, S.; Brooke, G. N.; Klenova, E.; Zhurkin, V. B.; Teif, V. B.
10.1101/2023.04.17.537031 — genomics — Posted on 2023-10-19
1961 Bacterial surface lipoproteins mediate epithelial microinvasion by Streptococcus pneumoniae
Chan, J. M.; Ramos-Sevillano, E.; Betts, M.; Wilson, H. U.; Weight, C. M.; Houhou-Ousalah, A.; Pollara, G.; Brown, J. S.; Heyderman, R. S.
10.1101/2023.10.18.562909 — microbiology — Posted on 2023-10-19
1962 Regulatory Mimicry of Cyclin-Dependent Kinases by Conserved Herpesvirus Protein Kinases
Koyanagi, N.; Hengphasatporn, K.; Kato, A.; Nobe, M.; Takeshima, K.; Maruzuru, Y.; Maenaka, K.; Shigeta, Y.; Kawaguchi, Y.
10.1101/2023.10.18.563025 — microbiology — Posted on 2023-10-19
1963 Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike protein
Waki, K.; Tani, H.; Saga, Y.; Shimada, T.; Yamazaki, E.; Koike, S.; Okada, N.; Isobe, M.; Kurosawa, N.
10.1101/2023.04.10.536311 — immunology — Posted on 2023-10-19
1965 Evaluating flash freezing for preservation of rat abdominal aorta for delayed biomechanical characterization
van der Laan, K. W. F.; Reesink, K.; Lambrichts, S.; Bitsch, N. J. J. E.; van der Taelen, L.; Foulquier, S.; Delhaas, T.; Spronck, B.; Giudici, A.
10.1101/2023.10.16.562465 — bioengineering — Posted on 2023-10-19
1966 Ablation of Sam50 is associated with fragmentation and alterations in metabolism in murine and human myotubes
Shao, B.; Killion, M.; Oliver, A.; Vang, C.; Zeleke, F.; Neikirk, K.; Vue, Z.; Garza-Lopez, E.; Shao, J.-q.; Mungai, M.; Lam, J.; Williams, Q.; Altamura, C.; Whiteside, A.; Kabugi, K.; McKenzie, J.; Koh, A.; Scudese, E.; Vang, L.; Marshall, A. G.; Crabtree, A.; Tanghal, J. I.; Stephens, D. C.; Koh, H.-J.; Jenkins, B.; Murray, S. A.; Cooper, A.; Williams, C.; Damo, S. M.; McReynolds, M.; Gaddy, J. A.; Gaddy, J.; Wanjalla, C. N.; Beasley, H. K.; Hinton, A.
10.1101/2023.05.20.541602 — physiology — Posted on 2023-10-19
1967 Transertion and cell geometry organize the Escherichia coli nucleoid during rapid growth
Spahn, C.; Middlemiss, S.; Gomez-de-Mariscal, E.; Henriques, R.; Bode, H. B.; Holden, S.; Heilemann, M.
10.1101/2023.10.16.562172 — microbiology — Posted on 2023-10-19
1969 Angiogenic Steroids Induce Pathologic Scarring in a Preclinical Swine Model Via Dysfunctional Extracellular Matrix Deposition.
Reiche, E.; Keller, P. R.; Soares, V.; Schuster, C. R.; Rahmayanti, S.; Mroueh, J.; Mroueh, V.; Billaud, M.; Hu, S.; Hoover-Watson, H.; Lian, C. G.; Tan, Y.; Doloff, J. C.; Newell-Fugate, A. E.; Coon, D.
10.1101/2023.05.29.542765 — systems biology — Posted on 2023-10-19
1974 DNABERT-based explainable lncRNA identification in plant genome assemblies
Danilevicz, M. F.; Gill, M.; Tay Fernandez, C. G.; Petereit, J.; Upadhyaya, S. R.; Batley, J.; Bennamoun, M.; Edwards, D.; Bayer, P. E.
10.1101/2022.02.09.479647 — bioinformatics — Posted on 2023-10-19
1975 Semi-rational evolution of a recombinant DNA polymerase for modified nucleotide incorporation efficiency
ZHAI, L.; Wang, Z.; Liu, F.; Xu, C.; Wang, J.; Han, H.; Xie, Q.; Zhang, W.; Zheng, Y.; Buell, A. K.; Dong, Y.
10.1101/2023.03.20.533374 — bioengineering — Posted on 2023-10-19
1976 Heat n Beat: A universal high-throughput end-to-end proteomics sample processing platform in under an hour
Xavier, D.; Lucas, N.; Williams, S. G.; Koh, J. M. S.; Ashman, K.; Loudon, C.; Reddel, R.; Hains, P. G.; Robinson, P. J.
10.1101/2023.09.27.559846 — biochemistry — Posted on 2023-10-19
1977 The landscape of genomic structural variation in Indigenous Australians
Reis, A. M.; Rapadas, M.; Hammond, J. M.; Gamaarachchi, H.; Stevanovski, I.; Kumaheri, M.; Chintalaphani, S.; Dissanayake, D.; Brown, A.; Llamas, B.; Hewitt, A.; Brown, A.; Baynam, G.; Mann, G.; Hermes, A.; Patel, H. R.; Deveson, I. W.
10.1101/2023.10.17.562810 — genomics — Posted on 2023-10-19
1978 A single cell trajectory of human archetypal pluripotent stem cell differentiation to trophoblast stem cells reveals induction of endogenous BMP5/7 and GATA3 without transitioning through a naive state
Tietze, E.; Barbosa, A. R.; Araujo, B. H. S.; Euclydes, V.; Cho, H. J.; Lee, Y. K.; Feltrin, A.; Spiegelberg, B.; Lorenzetti, A.; Leemput, J. v. d.; Carlo, P. D.; Sawada, T.; Ursini, G.; Benjamin, K. J.; Brentani, H.; Kleinman, J. E.; Hyde, T. M.; Weinberger, D. A.; McKay, R.; Shin, J. H.; Paquola, A. C. M.; Erwin, J. A.
10.1101/2020.08.29.273425 — developmental biology — Posted on 2023-10-19
1979 Recombinant biosensors for multiplex and super-resolution imaging of phosphoinositides
Maib, H.; Adarska, P.; Hunton, R.; Vines, J.; Strutt, D.; Bottanelli, F.; Murray, D. H.
10.1101/2023.10.18.562882 — cell biology — Posted on 2023-10-19
1981 Speech induces spatiotemporal and frequency specific subthalamic-cortical spike-phase coupling events
Vissani, M.; Bush, A.; Lipski, W. J.; Fischer, P.; Neudorfer, C.; Holt, L. L.; Fiez, J. A.; Turner, R. S.; Richardson, R. M.
10.1101/2023.10.18.562969 — neuroscience — Posted on 2023-10-19
1985 Encoding of melody in the human auditory cortex
Sankaran, N.; Leonard, M. K.; Theunissen, F. E.; Chang, E. F.
10.1101/2023.10.17.562771 — neuroscience — Posted on 2023-10-19
1986 Dogs' sensory-motor tuning shapes dog-human vocal interactions
DEAUX, E.; Piette, T.; Gaunet, F.; Legou, T.; Arnal, L.; Giraud, A.-L.
10.1101/2023.10.18.562860 — neuroscience — Posted on 2023-10-19
1987 Selective Vulnerability of Layer 5a Corticostriatal Neurons in Huntington's Disease
Pressl, C.; Mätlik, K.; Kus, L.; Darnell, P.; Luo, J.-D.; Paul, M. R.; Weiss, A. R.; Liguore, W.; Carroll, T.; Davis, D. A.; McBride, J.; Heintz, N.
10.1101/2023.04.24.538096 — neuroscience — Posted on 2023-10-19
1989 Systematic mining and functional analysis of factors regulating wheat spike development for breeding selection
Lin, X.; Xu, Y.; Wang, D.; Yang, Y.; Zhang, X.; Bie, X.; Chen, Z.; Ding, Y.; Mao, L.; Zhang, X.; Lu, F.; Zhang, X.; Uauy, C.; Fu, X.; Xiao, J.
10.1101/2022.11.11.516122 — plant biology — Posted on 2023-10-19
1990 Identification of the KIF18A alpha-4 helix as a therapeutic target for chromosomally unstable tumor cells
Schutt, K.; Queen, K. A.; Fisher, K.; Budington, O.; Mao, W.; Liu, W.; Xiao, Y.; Aswad, F.; Joseph, J.; Stumpff, J.
10.1101/2023.10.16.562576 — cancer biology — Posted on 2023-10-19
1992 Epigenome erosion in Alzheimer's disease brain cells and induced neurons
Wang, B.; Jones, J.; Zhou, J.; Tian, W.; Wu, Y.; Wang, W.; Berube, P.; Bartlett, A.; Castanon, R. G.; Nery, J. R.; Chen, H.; Kenworthy, M.; Altshul, J.; Valadon, C.; Wang, Y.; Kang, A.; Goodman, R.; Liem, M.; Claffey, N.; O'Connor, C.; Metcalf, J.; Luo, C.; Gage, F. H.; Ecker, J. R.
10.1101/2023.10.15.562394 — genomics — Posted on 2023-10-18
1994 A Bioluminescent Activity Dependent (BLADe) Platform for Converting Neuronal Activity to Photoreceptor Activation
Crespo, E. L.; Pal, A.; Prakash, M.; Silvagnoli, A. D.; Zaidi, Z.; Gomez-Ramirez, M.; Tree, M. O.; Shaner, N. C.; Lipscombe, D.; Moore, C. I.; Hochgeschwender, U.
10.1101/2023.06.25.546469 — neuroscience — Posted on 2023-10-18
1995 Ghost interactions: revealing missing protein-ligand interactions using AlphaFold predictions
Escobedo, N.; Saldano, T. E.; Mac Donagh, J.; Rodriguez Sawicki, L.; Palopoli, N.; Fernandez Alberti, S.; Fornasari, M. S.; Parisi, G.
10.1101/2023.10.18.561916 — bioinformatics — Posted on 2023-10-18
1996 Polinton-like Viruses Associated with Entomopoxviruses Provide Insight into Replicon Evolution
Barth, Z. K.; Hicklin, I.; Theze, J.; Takatsuka, J.; Nakai, M.; Herniou, E. A.; Brown, A. M.; Aylward, F. O.
10.1101/2023.10.16.562556 — genomics — Posted on 2023-10-18
1999 The sensor of the bacterial histidine kinase CpxA is a novel dimer of extracytoplasmic Per-ARNT-Sim (PAS) domains
Cho, T. H. S.; Murray, C.; Malpica, R.; Margain-Quevedo, R.; Thede, G. L.; Lu, J.; Edwards, R. A.; Glover, J. N. M.; Raivio, T. L.
10.1101/2023.10.18.561931 — molecular biology — Posted on 2023-10-18
2001 Nucleo-cytoplasmic environment modulates spatio-temporal p53 phase separation
Datta, D.; Navalkar, A.; Sakunthala, A.; Paul, A.; Patel, K.; Masurkar, S.; Gadhe, L.; Sengupta, S.; Poudyal, M.; Devi, J.; Sawner, A. S.; Kadu, P.; Shaw, R.; Pandey, S.; Mukherjee, S.; Gahlot, N.; Sengupta, K.; Maji, S. K.
10.1101/2023.10.16.562512 — biophysics — Posted on 2023-10-18
2009 Mechanical characterization of regenerating Hydra tissue spheres
Perros, T.; Biquet-Bisquert, A.; Ben Meriem, Z.; Delarue, M.; Joseph, P.; Marcq, P.; Cochet-Escartin, O.
10.1101/2023.10.16.562504 — biophysics — Posted on 2023-10-18
2010 Insights into Drug Cardiotoxicity from Biological and Chemical Data: The First Public Classifiers for FDA DICTrank
Seal, S.; Spjuth, O.; Hosseini-Gerami, L.; Garcia-Ortegon, M.; Singh, S.; Bender, A.; Carpenter, A. E.
10.1101/2023.10.15.562398 — bioinformatics — Posted on 2023-10-18
2014 High-throughput single-cell sorting by stimulated Raman-activated cell ejection
Zhang, J.; Lin, H.; Xu, J.; Zhang, M.; Ge, X.; Zhang, C.; Huang, W.; Cheng, J.-X.
10.1101/2023.10.16.562526 — bioengineering — Posted on 2023-10-18
2015 Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy
Guo, M.; Wu, Y.; Su, Y.; Qian, S.; Krueger, E.; Christensen, R.; Kroeschell, G.; Bui, J.; Chaw, M.; Zhang, L.; Liu, J.; Hou, X.; Han, X.; Ma, X.; Zhovmer, A.; Combs, C.; Moyle, M.; Yemini, E.; Liu, H.; Liu, Z.; La Riviere, P.; Colon-Ramos, D.; Shroff, H.
10.1101/2023.10.15.562439 — bioengineering — Posted on 2023-10-18
2017 A multistate capture-recapture model to estimate cause-specific injury and mortality of North Atlantic right whales
Linden, D. W.; Hostetler, J. A.; Pace, R. M.; Garrison, L. P.; Knowlton, A. R.; Lesage, V.; Williams, R.; Runge, M. C.
10.1101/2023.10.15.562416 — ecology — Posted on 2023-10-18
2019 Exercise Training and Cold Exposure Trigger Distinct Molecular Adaptations to Inguinal White Adipose Tissue
Vamvini, M.; Nigro, P.; Caputo, T.; Stanford, K. I.; Hirshman, M. F.; Middelbeek, R. J. W.; Goodyear, L. J.
10.1101/2023.10.16.562635 — physiology — Posted on 2023-10-18
2021 De novo generation of antibody CDRH3 with a pre-trained generative large language model
He, H.; He, B.; Guan, L.; Zhao, Y.; Chen, G.; Zhu, Q.; Chen, C. Y.-C.; Li, T.; Yao, J.
10.1101/2023.10.17.562827 — bioinformatics — Posted on 2023-10-18
2024 A gene with a thousand alleles: the HYPer-variable effectors of plant-parasitic nematodes
Sonawala, U.; Beasley, H.; Thorpe, P. J.; Varypatakis, K.; Senatori, B.; Jones, J. T.; Derevnina, L.; Eves-van den Akker, S.
10.1101/2023.10.16.561705 — genetics — Posted on 2023-10-18
2025 Electrophysiological characterisation of iPSC-derived human β-like cells and an SLC30A8 disease model.
Jaffredo, M.; Krentz, N. A. J.; Champon, B.; Duff, C. E.; Nawaz, S.; Beer, N.; Honore, C.; Clark, A.; Rorsman, P.; Lang, J.; Gloyn, A. L.; Raoux, M.; Hastoy, B.
10.1101/2023.10.17.561014 — cell biology — Posted on 2023-10-18
2026 GRAMD2+ alveolar type I cell plasticity facilitates cell state transitions in organoid culture
Shen, H.; Chen, W.; Liu, Y.; Castaldi, A.; Castillo, J.; Horie, M.; Flodby, P.; Sundar, S.; Li, C.; Ji, Y.; Minoo, P.; Marconett, C. N.; Zhou, B.; Borok, Z.
10.1101/2023.10.17.560801 — cell biology — Posted on 2023-10-18
2027 Precise immunofluorescence canceling for highly multiplexed imaging capturing specific cell state
Tomimatsu, K.; Fujii, T.; Bise, R.; Hosoda, K.; Taniguchi, Y.; Ochiai, H.; Ohishi, H.; Ando, K.; Minami, R.; Taro, T.; Tanaka, K.; Mori, S.; Harada, A.; Maehara, K.; Nagasaki, M.; Uchida, S.; Kimura, H.; Narita, M.; Ohkawa, Y.
10.1101/2023.10.17.561810 — cell biology — Posted on 2023-10-18
2029 Arrayed in vivo barcoding for multiplexed sequence verification of plasmid DNA and demultiplexing of pooled libraries
Li, W.; Miller, D.; Liu, X.; Tosi, L.; Chkaiban, L.; Mei, H.; Hung, P.-H.; Parekkadan, B.; Sherlock, G.; Levy, S. F.
10.1101/2023.10.13.562064 — synthetic biology — Posted on 2023-10-18
2030 Photosynthesis drives retention of bacterial-like tRNA metabolism in plant organelles
DeTar, R. A.; Chustecki, J.; Martinez-Hottovy, A.; Cerrioti, L. F.; Broz, A. K.; Sanchez-Puerta, M. V.; Elowsky, C.; Christensen, A. C.; Sloan, D. B.
10.1101/2023.08.01.551541 — plant biology — Posted on 2023-10-18
2032 PhISCO: a simple method to infer phenotypes from protein sequences
Berthet, A. S. H.; Aptekmann, A. A.; bravo, j. t.; Sanchez, I. E.; Noguera, M. E.; Roman, E. A.
10.1101/2022.10.23.511734 — biophysics — Posted on 2023-10-18
2033 False discovery rates of qpAdm-based screens for genetic admixture
Yüncü, E.; Isıldak, U.; Williams, M. P.; Huber, C. D.; Flegontova, O.; Vyazov, L. A.; Changmai, P.; Flegontov, P.
10.1101/2023.04.25.538339 — genetics — Posted on 2023-10-18
2035 Reorganization of the Flagellum Scaffolding Induces a Sperm Standstill During Fertilization
Jablonski, M.; Luque, G. M.; Gomez-Elias, M.; Sanchez-Cardenas, C.; Xu, X.; de la Vega-Beltran, J. L.; Corkidi, G.; Linares, A.; Abonza, V.; Krapf, D.; Krapf, D.; Darszon, A.; Guerrero, A.; Buffone, M. G.
10.1101/2023.06.22.546073 — cell biology — Posted on 2023-10-18
2036 A diverse network of pericoerulear neurons control arousal states
Luskin, A. T.; Li, L.; Fu, X.; Barcomb, K.; Blackburn, T.; Martin, M.; Li, E. M.; Rana, A.; Simon, R. C.; Sun, L.; Murry, A. D.; Golden, S. A.; Stuber, G. D.; Ford, C. P.; Gu, L.; Bruchas, M. R.
10.1101/2022.06.30.498327 — neuroscience — Posted on 2023-10-18
2037 Engineering Logical Inflammation Sensing Circuit for Modulating Gut Conditions
Merk, L. N.; Shur, A. S.; Jena, S.; Munoz, J.; Brubaker, D.; Murray, R. M.; Green, L. N.
10.1101/2020.11.10.377085 — synthetic biology — Posted on 2023-10-18
2038 Deconstructing Intratumoral Heterogeneity through Multiomic and Multiscale Analysis of Serial Sections
Schupp, P. G.; Shelton, S. J.; Brody, D. J.; Eliscu, R.; Johnson, B. E.; Mazor, T.; Kelley, K. W.; Potts, M. B.; McDermott, M. W.; Huang, E. J.; Lim, D. A.; Pieper, R. O.; Berger, M. S.; Costello, J. F.; Phillips, J. J.; Oldham, M. C.
10.1101/2023.06.21.545365 — cancer biology — Posted on 2023-10-18
2039 The Selection Landscape and Genetic Legacy of Ancient Eurasians
Irving-Pease, E. K.; Refoyo-Martinez, A.; Barrie, W.; Ingason, A.; Pearson, A.; Fischer, A.; Sjögren, K.-G.; Halgren, A. S.; Macleod, R.; Demeter, F.; Henriksen, R. A.; Vimala, T.; McColl, H.; Vaughn, A.; Speidel, L.; Stern, A. J.; Scorrano, G.; Ramsoe, A.; Schork, A. J.; Rosengren, A.; Zhao, L.; Kristiansen, K.; Iversen, A. K. N.; Fugger, L.; Sudmant, P. H.; Lawson, D. J.; Durbin, R.; Korneliussen, T.; Werge, T.; Allentoft, M. E.; Sikora, M.; Nielsen, R.; Racimo, F.; Willerslev, E.
10.1101/2022.09.22.509027 — evolutionary biology — Posted on 2023-10-18
2040 Protective Role of RIPK1 Scaffolding against HDV-Induced Hepatocyte cell death and the Significance of Cytokines in Mice
Camps, G.; Maestro, S.; Torella, L.; Usai, C.; Aldaz, A.; Olague, C.; Vales, A.; Montfort, A.; Segui, B.; Suarez, L.; Aldabe, R.; Gonzalez-Aseguinolaza, G.
10.1101/2023.10.15.562448 — pathology — Posted on 2023-10-18
2041 Hippo effector, Yorkie, is a Tumor Suppressor in Select Drosophila Squamous Epithelia
Bhattacharya, R.; Kumari, J.; Banerjee, S.; Tripathi, J.; Mohan, N.; SINHA, P.
10.1101/2023.10.15.562319 — cancer biology — Posted on 2023-10-18
2043 Development of covalent chemogenetic K2P channel activators
Deal, P. E.; Lee, H.; Mondal, A.; Lolicato, M.; Furtado de Mandonca, P. R.; Black, H.; El-Hilali, X.; Bryant, C.; Isacoff, E. Y.; Renslo, A.; Minor, D. L.
10.1101/2023.10.15.561774 — biophysics — Posted on 2023-10-18
2046 A Non-invasive Detection of Parkinson's Disease using PitArray: An Integrative Meta-Analysis and Machine Learning Approach
Bhattacharjee, A.; Jamal, T. B.; Ahammad, I.; Lamisa, A. B.; Arefin, M. S.; Chowdhury, Z. M.; Hossain, M. U.; Das, K. C.; Keya, C. A.; Salimullah, M.
10.1101/2023.10.15.562440 — bioinformatics — Posted on 2023-10-18
2047 Epigenome erosion in Alzheimer's disease brain cells and induced neurons
Ecker, J. R.; Gage, F. H.; Wang, B.; Jones, J.; Zhou, J.; Tian, W.; Wu, Y.; Wang, W.; Berube, P.; Bartlett, A.; Castanon, R. G.; Nery, J. R.; Chen, H.; Kenworthy, M.; Altshul, J.; Valadon, C.; Wang, Y.; Kang, A.; Goodman, R.; Liem, M.; Claffey, N.; O'Connor, C.; Metcalf, J.; Luo, C.
10.1101/2023.10.15.562394 — genomics — Posted on 2023-10-18
2048 Divergent selection for feed efficiency in pigs altered the duodenum transcriptome and DNA methylation profiles, resulting in greater responses to feed intake in the most efficient line
Devailly, G.; Feve, K.; Saci, S.; Sarry, J.; Valiere, S.; Lluch, J.; Bouchez, O.; Ravon, L.; Billon, Y.; Gilbert, H.; Riquet, J.; Beaumont, M.; Demars, J.
10.1101/2022.11.03.515018 — genomics — Posted on 2023-10-18
2054 Fornix fractional anisotropy mediates the association between Mediterranean diet adherence and memory four years later in older adults without dementia
Ruiz-Rizzo, A. L.; Finke, K.; Damoiseaux, J. S.; Bartels, C.; Buerger, K.; Cosma, N. C.; Dechent, P.; Dobisch, L.; Ewers, M.; Fliessbach, K.; Frommann, I.; Glanz, W.; Goerss, D.; Hetzer, S.; Incesoy, E. I.; Janowitz, D.; Kilimann, I.; Laske, C.; Melo van Lent, D.; Munk, M. H. J.; Peters, O.; Priller, J.; Ramirez, A.; Rostamzadeh, A.; Roy, N.; Scheffler, K.; Schneider, A.; Spottke, A.; Spruth, E. J.; Teipel, S.; Wagner, M.; Wiltfang, J.; Yakupov, R.; Jessen, F.; Duezel, E.; Perneczky, R.; Rauchmann, B.-S.
10.1101/2023.03.31.534758 — neuroscience — Posted on 2023-10-18
2056 Insulin sensitization by hepatic FoxO deletion is insufficient to lower atherosclerosis in mice
Izquierdo, M. C.; Harris, M.; Shanmugarajah, N.; Zhong, K.; Ozcan, L.; Fredman, G.; Haeusler, R. A.
10.1101/2023.10.14.562366 — physiology — Posted on 2023-10-18
2057 Clinically relevant humanized mouse models of metastatic prostate cancer to evaluate cancer therapies
Kostlan, R. J.; Phoenix, J. T.; Budreika, A.; Ferrari, M. G.; Khurana, N.; Choi, J. E.; Juckette, K.; McCollum, B. L.; Moskal, R.; Qiao, Y.; Vander Griend, D. J.; Chinnaiyan, A. M.; Kregel, S.
10.1101/2023.10.13.562280 — cancer biology — Posted on 2023-10-18
2058 Mutant mice lacking alternatively spliced p53 isoforms unveil Ackr4 as a male-specific prognostic factor in Myc-driven B-cell lymphomas
Fajac, A.; Simeonova, I.; Leemput, J.; Gabriel, M.; Morin, A.; Lejour, V.; Hamon, A.; Vaysse-Zinkhofer, W.; Eldawra, E.; Rakotopare, J.; Pinskaya, M.; Morillon, A.; Bourdon, J.-C.; Bardot, B.; Toledo, F.
10.1101/2023.10.13.562180 — cancer biology — Posted on 2023-10-18
2060 Childhood cancer mutagenesis caused by a domesticated DNA transposase
Keller, R.; Yamada, M.; Cameron, D.; Suzuki, H.; Sanghrajka, R.; Vaynshteyn, J.; Gerwin, J.; Maura, F.; Hooper, W.; Shah, M.; Robine, N.; Demarest, P.; Bayin, N. S.; Jubierre, L.; Taylor, M. D.; Joyner, A. L.; Raju, P. G.; Kentsis, A.
10.1101/2022.07.05.498128 — cancer biology — Posted on 2023-10-18
2063 TALEN-induced contraction of CTG trinucleotide repeats in myotonic dystrophy type 1 cells
Betemps, L.; Descorps-Declere, S.; Frenoy, O.; Poggi, L.; Mosbach, V.; Tome, S.; Viterbo, D.; Klein, A.; Ma, L.; Cokelaer, T.; Monot, M.; Dumas, B.; Gourdon, G.; Furling, D.; Richard, G.-F.
10.1101/2023.10.14.562330 — genomics — Posted on 2023-10-18
2064 Evolution of novel sensory organs in fish with legs
Allard, C. A.; Herbert, A. L.; Krueger, S. P.; Liang, Q.; Walsh, B. L.; Rhyne, A.; Gourlay, A.; Seminara, A.; Baldwin, M. W.; Kingsley, D. M.; Bellono, N.
10.1101/2023.10.14.562285 — evolutionary biology — Posted on 2023-10-18
2065 Competing adaptations maintain non-adaptive variation in a wild cricket population
Rayner, J. G.; Eichenberger, F.; Bainbridge, J. V. A.; Zhang, S.; Zhang, X.; Yusuf, L.; Balenger, S.; Gaggiotti, O. E.; Bailey, N. W.
10.1101/2023.10.14.562337 — evolutionary biology — Posted on 2023-10-18
2066 Progesterone induces meiosis through two obligate co-receptors with PLA2 activity
Nader, N.; Zarif, L.; Halama, A.; Yadav, S.; Dib, M.; Attarwala, N.; Chen, Q.; Suhre, K.; Gross, S. S.; Machaca, K.
10.1101/2023.09.09.556646 — cell biology — Posted on 2023-10-18
2067 PAK1 and NF2/Merlin jointly drive myelination by remodeling actin cytoskeleton in oligodendrocytes
Baudouin, L.; Ades, N.; Kante, K.; Bachelin, C.; Hmidan, H.; Deboux, C.; Panic, R.; Ben Messaoud, R.; Hamada, S.; Pionneau, C.; Velut, Y.; Duarte, K.; Poën-Guyon, S.; Barnier, J.-V.; Nait Oumesmar, B.; Bouslama-Oueghlani, L.
10.1101/2023.10.16.555467 — neuroscience — Posted on 2023-10-18
2068 A blue-shifted genetically encoded Ca2+ indicator with enhanced two-photon absorption
Aggarwal, A.; Sunil, S.; Bendifallah, I.; Moon, M.; Drobizhev, M.; Zarowny, L.; Zheng, J.; Wu, S.-Y.; Lohman, A.; Tebo, A.; EMILIANI, V.; Podgorski, K.; Shen, Y.; Campbell, R.
10.1101/2023.10.12.562058 — neuroscience — Posted on 2023-10-18
2073 Structural insights into the distinct protective mechanisms of human antibodies targeting ZIKV NS1
Pan, Q.; Xiong, X.; Yu, J.; Chen, Q.; Jiao, H.; Zhang, W.; Wen, Y.; Gao, M.; Zhao, W.; Yu, L.; Hu, H.
10.1101/2023.10.16.562450 — microbiology — Posted on 2023-10-18
2075 PD-L1 Restrains the PD-1hiNrp1loTGFb+ Treg to block IL6+ Neutrophil tumor infiltration to Suppress Inflammation-driven Colorectal Cancer
Liu, K.; Poschel, D. B.; Klement, J.; Merting, A. D.; Lu, C.; Zhao, Y.; Yang, D.; Xiao, W.; Zhu, H.; Rajeshwari, P.; Toscano, M.; Jones, K.; Madwani, K.; Barret, A.; Bollag, R.; Fallon, P. G.; Shi, H.
10.1101/2023.10.12.562132 — immunology — Posted on 2023-10-18
2077 Glomerular immune injury promotes anti-tumor activity
Avraham, S.; Korin, B.; Hung-Hao Lo, J.; Cruz Tleugabulova, M.; Menon, H.; Darmanis, S.; Liang, Y.; Modrusan, Z.; Durinck, S.; Webster, J. D.; Shaw, A. S.
10.1101/2023.10.14.562333 — cancer biology — Posted on 2023-10-18
2078 Tissue-resident NK cells support survival in pancreatic cancer through promotion of cDC1-CD8T activity
Go, S.; Demetriou, C.; Hughes, S.; Lanfredini, S.; Valenzano, G.; Ferry, H.; Arbe-Barnes, E.; Sivakumar, S.; Bashford-Rogers, R.; Middleton, M. R.; Mukherjee, S.; Morton, J.; Jones, K.; O'Neill, E.
10.1101/2023.10.14.562332 — cancer biology — Posted on 2023-10-18
2079 An Automated and Robust Tool for Musculoskeletal and Finite Element Modeling of the Knee Joint
Esrafilian, A.; Chandra, S.; Gatti, A. A.; Nissi, M. J.; Mustonen, A.-M.; Saisanen, L.; Reijonen, J.; Nieminen, P.; Julkunen, P.; Toyras, J.; Saxby, D. J.; Lloyd, D. G.; Korhonen, R. K.
10.1101/2023.10.14.562320 — bioengineering — Posted on 2023-10-18
2080 Quantification of the escape from X chromosome inactivation with the million cell-scale human single-cell omics datasets reveals heterogeneity of escape across cell types and tissues
Tomofuji, Y.; Edahiro, R.; Shirai, Y.; Kock, K. H.; Sonehara, K.; Wang, Q. S.; Namba, S.; Moody, J.; Ando, Y.; Suzuki, A.; Yata, T.; Ogawa, K.; Namkoong, H.; Lin, Q. X. X.; Buyamin, E. V.; Tan, L. M.; Sonthalia, R.; Han, K. Y.; Tanaka, H.; Lee, H.; Asian Immune Diversity Atlas Network, ; Japan COVID-19 Task Force, ; The BioBank Japan Project, ; Okuno, T.; Liu, B.; Matsuda, K.; Fukunaga, K.; Mochizuki, H.; Park, W.-Y.; Yamamoto, K.; Hon, C.-C.; Shin, J. W.; Prabhakar, S.; Kumanogoh, A.; Okada, Y.
10.1101/2023.10.14.561800 — genomics — Posted on 2023-10-18
2081 Human organoid model of PCH2a recapitulates brain region-specific pathology
Kagermeier, T.; Hauser, S.; Sarieva, K.; Laugwitz, L.; Groeschel, S.; Janzarik, W.; Yentuer, Z.; Becker, K.; Schoels, L.; Kraegeloh-Mann, I.; Mayer, S.
10.1101/2022.10.13.512020 — neuroscience — Posted on 2023-10-18
2082 Evaluation of trans- and cis-4-fluorogabapentin for brain PET imaging
Zhou, Y.-P.; Normandin, M. D.; Belov, V.; Macdonald-Soccorso, M. T.; Moon, S.-H.; Sun, Y.; El Fakhri, G.; Guehl, N. J.; Brugarolas, P.
10.1101/2023.09.01.555353 — neuroscience — Posted on 2023-10-18
2083 Recommendations For a Standardized Approach to Histopathologic Evaluation of Synovial Membrane in Murine Models of Experimental Osteoarthritis
Obeidat, A. M.; Kim, S. Y.; Burt, K. G.; Hu, B.; Li, J.; Ishihara, S.; Xiao, R.; Miller, R. E.; Little, C. B.; Malfait, A.-M.; Scanzello, C.
10.1101/2023.10.14.562259 — pathology — Posted on 2023-10-18
2085 MSclassifR: an R package for supervised classification of mass spectra with machine learning methods
Godmer, A.; Benzerara, Y.; Varon, E.; Veziris, N.; Druart, K.; Mozet, R.; Matondo, M.; Aubry, A.; Giai Gianetto, Q.
10.1101/2022.03.14.484252 — bioinformatics — Posted on 2023-10-18
2088 Systematic perturbations of SETD2, NSD1, NSD2, NSD3 and ASH1L reveals their distinct contributions to H3K36 methylation
Shipman, G.; Padilla, R.; Horth, C.; Hu, B.; Bareke, E.; Vitorino, F.; Gongora, J.; Garcia, B.; Lu, C.; Majewski, J.
10.1101/2023.09.27.559313 — genomics — Posted on 2023-10-18
2090 Gene-level alignment of single cell trajectories
Sumanaweera, D.; Suo, C.; Cujba, A.-M.; Muraro, D.; Dann, E.; Polanski, K.; Steemers, A. S.; Lee, W.; Oliver, A. J.; Park, J.-E.; Meyer, K. B.; Dumitrascu, B.; Teichmann, S. A.
10.1101/2023.03.08.531713 — bioinformatics — Posted on 2023-10-18
2092 The increased hinge flexibility of an IgG1-IgG3 hybrid monoclonal enhances Fc-mediated protection against group A streptococci
Izadi, A.; Karami, Y.; Bratanis, E.; Wrighton, S.; Khakzad, H.; Nyblom, M.; Olofsson, B.; Happonen, L.; Tang, D.; Nilges, M.; Malmström, J.; Bahnan, W.; Shannon, O.; Malmström, L.; Nordenfelt, P.
10.1101/2023.10.14.562368 — immunology — Posted on 2023-10-18
2096 MFSD7c functions as a transporter of choline at the blood-brain barrier
Nguyen, X. T. A.; Le, U. T. N.; Ha, H. T. T.; Nguyen, T. Q.; Artati, A.; Leong, N. C. P.; Nguyen, D. T.; Lim, P. Y.; Susanto, A. V.; Huang, Q.; Fam, L.; Leong, N. L.; Bonne, I.; Lee, A.; Gooch, C.; Granadillo De Luque, J. L.; Yu, D.; Hua, H.; Soong, T. W.; Chang, M. W.; Wenk, M. R.; Jerzy, A.; Cazenave-Gassiot, A.; Nguyen, L. N.
10.1101/2023.10.03.560597 — biochemistry — Posted on 2023-10-18
2097 Inhibition of the glucocorticoid-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 drives concurrent 11-oxygenated androgen excess
Schiffer, L.; Oestlund, I.; Snoep, J.; Gilligan, L. C.; Taylor, A. E.; Sinclair, A. J.; Singhal, R.; Freeman, A.; Ajjan, R.; Tiganescu, A.; Arlt, W.; Storbeck, K.-H.
10.1101/2023.06.05.543687 — biochemistry — Posted on 2023-10-18
2101 The Influence of Angiotensin II on the Gut Microbiome of Mice: Findings from a Retrospective Study
R Muralitharan, R.; Nakai, M.; Snelson, M.; Zheng, T.; Dinakis, E.; Xie, L.; Jama, H.; Paterson, M.; Shihata, W.; Wassef, F.; Vinh, A.; Drummond, G. R.; Kaye, D. M.; Mackay, C. R.; Marques, F. Z.
10.1101/2023.04.08.536089 — microbiology — Posted on 2023-10-18
2102 Asparagine availability controls B cell homeostasis
Yazicioglu, Y. F.; Marin, E.; Bentkowska, K.; Andrew, H.; Mitchell, R.; Wong, Z. Y.; Fergusson, J.; Kronsteiner, B.; Ali, M.; Coles, M.; Buckley, C.; Dunachie, S.; Clarke, A.
10.1101/2023.04.03.535433 — immunology — Posted on 2023-10-18
2103 Assessing the link between tissue elasticity and plant growth
Laplaud, V.; Demidova, N.; Muller, E.; Drevensek, S.; Boudaoud, A.
10.1101/2023.09.21.558781 — biophysics — Posted on 2023-10-18
2104 Automated cell type annotation and exploration of single-cell signalling dynamics using mass cytometry
Kleftogiannis, D.; Tislevoll, B. S.; van der Meer, N.; Motzfeldt, I. K. F.; Hellesoy, M.; Gullaksen, S.-E.; Griessinger, E.; Fagerholt, O.; Lenartova, A.; Floisand, Y.; Schuringa, J. J.; Gjertsen, B. T.; Jonassen, I.
10.1101/2022.08.13.503587 — bioinformatics — Posted on 2023-10-18
2105 CFSA: Comparative Flux Sampling Analysis as a guide for strain design
van Rosmalen, R. P.; Moreno-Paz, S.; Duman-Ozdamar, E. Z.; Suarez-Diez, M.
10.1101/2023.06.15.545085 — bioengineering — Posted on 2023-10-18
2112 Network level enrichment provides a framework for biological interpretation of machine learning results
Li, J.; Segel, A.; Feng, X.; Tu, J. C.; Eck, A.; King, K.; Adeyemo, B.; Karcher, N. R.; Chen, L.; Eggebrecht, A. T.; Wheelock, M. D.
10.1101/2023.10.14.562358 — neuroscience — Posted on 2023-10-17
2113 A General Single-Cell Analysis Framework via Conditional Diffusion Generative Models
Tang, W.; Liu, R.; Wen, H.; Dai, X.; Ding, J.; Li, H.; Fan, W.; Xie, Y.; Tang, J.
10.1101/2023.10.13.562243 — bioinformatics — Posted on 2023-10-17
2118 Identification of Key Yeast Species and Microbe-Microbe Interactions Impacting Larval Growth of Drosophila in the Wild
Mure, A.; Sugiura, Y.; Maeda, R.; Honda, K.; Sakurai, N.; Takahashi, Y.; Watada, M.; Katoh, T.; Gotoh, A.; Gotoh, Y.; Taniguchi, I.; Nakamura, K.; Hayashi, T.; Katayama, T.; Uemura, T.; Hattori, Y.
10.1101/2023.08.01.551563 — developmental biology — Posted on 2023-10-17
2120 Data-driven motif discovery in biological neural networks
Matelsky, J. K.; Robinette, M. R.; Wester, B.; Gray-Roncal, W. R.; Johnson, E. C.; Reilly, E. P.
10.1101/2023.10.16.562590 — neuroscience — Posted on 2023-10-17
2123 Highly specific σ2R/TMEM97 ligand alleviates neuropathic pain and inhibits the integrated stress response
Yousuf, M. S.; Sahn, J. J.; Yang, H.; David, E. T.; Shiers, S.; Mancilla Moreno,, M.; Iketem, J. B.; Royer, D. M.; Garcia, C. D.; Zhang, J.; Hong, V. M.; Mian, S. M.; Ahmad, A.; Kolber, B. J.; Liebl, D. J.; Martin, S. F.; Price, T. J.
10.1101/2023.04.11.536439 — neuroscience — Posted on 2023-10-17
2126 Surface Generative Modelling of Neurodevelopmental Trajectories
Fawaz, A.; Masui, S. N. B.; Williams, L. Z. J.; Dahan, S.; Edwards, D.; Robinson, E. C.
10.1101/2023.10.16.562598 — neuroscience — Posted on 2023-10-17
2131 Zinc-dependent Nucleosome Reorganization by PARP2
Maluchenko, N.; Saulina, A.; Geraskina, O.; Kotova, E.; Korovina, A.; Feofanov, A.; Studitsky, V.
10.1101/2023.10.17.562808 — biochemistry — Posted on 2023-10-17
2133 Probabilistic Graphical Modeling under Heterogeneity
Chen, L.; Acharyya, S.; Luo, C.; Ni, Y.; Baladandayuthapani, V.
10.1101/2023.10.13.562136 — genomics — Posted on 2023-10-17
2137 HERC3 E3 ligase provides an ERAD branch eliminating select membrane proteins
Kamada, Y.; Ohnishi, Y.; Nakashima, C.; Fujii, A.; Terakawa, M.; Hamano, I.; Nakayamada, U.; Katoh, S.; Hirata, N.; Tateishi, H.; Fukuda, R.; Takahashi, H.; Lukacs, G. L.; Okiyoneda, T.
10.1101/2023.10.16.562477 — cell biology — Posted on 2023-10-17
2140 Global regulation via modulation of ribosome pausing by EttA
Ousalem, F.; Ngo, S.; Oiffer, T.; Omairi-Nasser, A.; Monlezun, L.; Boel, G.
10.1101/2023.10.17.562674 — microbiology — Posted on 2023-10-17
2141 Mechanism of 2-Fucosyllactose degradation by Human-Associated Akkermansia
Fricker, A. D.; Padilla, L.; Luna, E.; Choudhury, B.; Hughes, E. R.; Panzetta, M. E.; Valdivia, R.; Flores, G. E.
10.1101/2023.10.17.562767 — microbiology — Posted on 2023-10-17
2144 Drosophila Bchs overexpression recapitulates human WDFY3 neurodevelopmental phenotypes with implications for glial cell involvement in altered head circumference
Koerner, M. B.; Velluva, A.; Bundalian, L.; Krohn, K.; Schoen, K.; Schumann, I.; Kromp, J.; Thum, A. S.; Garten, A.; Hentschel, J.; Abou Jamra, R.; Mrestani, A.; Scholz, N.; Langenhan, T.; Le Duc, D.
10.1101/2023.10.16.562295 — neuroscience — Posted on 2023-10-17
2147 Structural covariation between cerebellum and cerebral cortex is atypically modulated by thalamus in autism spectrum disorder
Uquillas, F. d.; Sefik, E.; Li, B.; Trotter, M.; Steele, K.; Seidlitz, J.; Gesue, R.; Latif, M.; Fasulo, T.; Zhang, V.; Kislin, M.; Verpeut, J.; Cohen, J.; Sepulcre, J.; Wang, S. S.- H.; Gomez, J.
10.1101/2023.10.16.562588 — neuroscience — Posted on 2023-10-17
2148 Chronic social defeat stress induces a depression-relevant outcome in male prairie voles
Rodriguez, M.; Themann, A.; Garcia-Carachure, I.; Lira, O.; Robison, A. J.; Cushing, B.; Iniguez, S. D.
10.1101/2023.10.16.562541 — neuroscience — Posted on 2023-10-17
2150 Listen to yourself: How motivational interviewing shifts food choices and craving-related brain responses to healthier options
Rodrigues, B.; Khalid, I.; Flament, B.; Frileux, S.; Rampanana, M.; Aubertin, H.; Rotge, J.-Y.; Fossati, P.; Koban, L.; Schmidt, L.
10.1101/2023.10.13.562241 — neuroscience — Posted on 2023-10-17
2152 The unique face of anxious depression: Increased sustained threat circuitry response during fear acquisition
Poplin, T.; Ironside, M.; Kuplicki, R.; Aupperle, R. L.; Guinjoan, S. M.; Khalsa, S. S.; Stewart, J. L.; Victor, T. A.; Paulus, M. P.; Kirlic, N.
10.1101/2023.10.17.562565 — neuroscience — Posted on 2023-10-17
2153 Aging Differentially Alters the Transcriptome and Landscape of Chromatin Accessibility in the Male and Female Mouse Hippocampus
Achiro, J. M.; Tao, Y.; Gao, F.; Lin, C.-H.; Watanabe, M.; Neumann, S.; Coppola, G.; Black, D. L.; Martin, K. C.
10.1101/2023.10.17.562606 — neuroscience — Posted on 2023-10-17
2155 Establishing an AI-based evaluation system that quantifies social/pathophysiological behaviors of common marmosets
Kaneko, T.; Matsumoto, J. M.; Lu, W.; Zhao, X.; Ueno-Nigh, L. R.; Oishi, T.; Kimura, K.; Otsuka, Y.; Zheng, A.; Ikenaka, K.; Baba, K.; Mochizuki, H.; Nishijo, H.; Inoue, K.-i.; Takada, M.
10.1101/2023.10.16.561623 — neuroscience — Posted on 2023-10-17
2159 Identification and neuroprotective properties of NA-184, a selective calpain-2 inhibitor
Baudry, M.; Wang, Y.; Bi, X.; Luo, Y.; Wang, Z.; Kamal, Z.; Shirokov, A.; Sullivan, E.; Lagasca, D.; Khalil, H.; Lee, G.; Fosnaugh, K.; Bey, P.; Medi, S.; Coulter, G.
10.1101/2023.10.16.562509 — neuroscience — Posted on 2023-10-17
2163 Neural activity ramps in frontal cortex signal extended motivation during learning
Regalado, J. M.; Corredera Asensio, A.; Haunold, T.; Toader, A. C.; Li, Y. R.; Neal, L. A.; Rajasethupathy, P.
10.1101/2023.10.15.562395 — neuroscience — Posted on 2023-10-17
2166 Restoring AIBP deficiency in the retina provides neuroprotection in glaucoma
Ju, W.-K.; Ha, Y.; Choi, S.; Kim, K.-Y.; Bastola, T.; Kim, J.; Weinreb, R. N.; Zhang, W.; Miller, Y. I.; Choi, S.-H.
10.1101/2023.10.16.562633 — neuroscience — Posted on 2023-10-17
2167 Allosteric regulation of a molecular motor through de novo protein design
Cross, J. A.; Dawson, W. M.; Shulka, S. R.; Weijman, J. F.; Mantell, J.; Dodding, M. P.; Woolfson, D. N.
10.1101/2023.10.17.562760 — synthetic biology — Posted on 2023-10-17
2168 Regulated Cleavage and Relocation of FERONIA Control Immunity in Arabidopsis Roots
Chen, J.; Qiang, X.; Liu, H.; Xu, F.; Wang, L.; Jiang, L.; Li, C.; Wang, B.; Luan, S.; Wu, D.; Zhou, F.; Yu, F.
10.1101/2023.10.16.562456 — plant biology — Posted on 2023-10-17
2171 BioKG: a comprehensive, high-quality biomedical knowledge graph for AI-powered, data-driven biomedical research
Zhang, Y.; Pan, F.; Sui, X.; Yu, K.; Li, K.; Tian, S.; Erdengasileng, A.; Han, Q.; Wang, W.; Wang, J.; Wang, J.; Sun, D.; Chung, H.; Zhou, J.; Zhou, E.; Lee, B.; Qiu, X.; Zhao, T.; Zhang, J.
10.1101/2023.10.13.562216 — bioinformatics — Posted on 2023-10-17
2172 Direct delivery of Cas9 or base editor protein and guide RNA complex enables genome editing in the retina
Botto, C.; Pulman, J.; Malki, H.; Ren, D.; Oudin, P.; De Cian, A.; As, M.; Izabelle, C.; Saubamea, B.; Fouquet, S.; Robert, C.; El-Amraoui, A.; FISSON, S.; Concordet, J.-P.; Dalkara, D.
10.1101/2023.10.16.562239 — bioengineering — Posted on 2023-10-17
2173 Cryo-EM structure of the CDK2-cyclin A-CDC25A complex
Rowland, R. J.; Korolchuk, S.; Salamina, M.; Ault, J. R.; Hart, S.; Turkenberg, J. P.; Blaza, J. N.; Noble, M. E.; Endicott, J. A.
10.1101/2023.10.17.562665 — biochemistry — Posted on 2023-10-17
2178 Xrs2 C-terminus mediates Tel1-dependent meiotic double-strand break interference
Dorme, M.; Aithal, R.; Vernerey, J.; Cayrou, C.; Geli, V.; llorente, b.; Garcia, V. C.
10.1101/2023.10.17.561996 — molecular biology — Posted on 2023-10-17
2179 Mechanisms of the FTO locus association with obesity: Irx3 controls a sumoylation-dependent switch between adipogenesis and osteogenesis
Bjune, J.-I.; Laber, S.; Lawrence-Archer, L.; Zhao, X.; Yamada, S.; Al-Sharabi, N.; Mustafa, K.; Njolstad, P. R.; Claussnitzer, M.; Cox, R. D.; Chymkowitch, P.; Mellgren, G.; Dankel, S. N.
10.1101/2023.10.17.562662 — molecular biology — Posted on 2023-10-17
2180 A purine salvage bottleneck leads to bacterial adenine cross-feeding
Chuang, Y.-C.; Haas, N. W.; Pepin, R.; Behringer, M.; Oda, Y.; LaSarre, B.; Harwood, C. S.; McKinlay, J. B.
10.1101/2023.10.17.562681 — microbiology — Posted on 2023-10-17
2185 A tale of two phage tails: Engineering the host range of bacteriophages infecting Clostridioides difficile
Steczynska, J. P.; Kerr, S. J.; Kelly, M. L.; Whittle, M. J.; Bilverstone, T. W.; Minton, N. P.
10.1101/2023.10.16.562632 — microbiology — Posted on 2023-10-17
2186 KatG catalase deficiency confers bedaquiline hyper-susceptibility to isoniazid resistant Mycobacterium tuberculosis
Ofori-Anyinam, N.; Hamblin, M.; Coldren, M. L.; Li, B.; Mereddy, G.; Shaikh, M.; Shah, A.; Ranu, N.; Lu, S.; Blainey, P. C.; Ma, S.; Collins, J. J.; Yang, J. H.
10.1101/2023.10.17.562707 — microbiology — Posted on 2023-10-17
2187 A mechanistic study on the tolerance of PAM distal end mismatch by SpCas9
Dey, D.; Chakravarti, R.; Bhattacharjee, O.; Majumder, S.; Chaudhuri, D.; Ahmed, K. T.; Bhattacharya, B.; Gautam, A.; Singh, R.; Gupta, R.; Ravichandiran, V.; Chattopadhyay, D.; Ghosh, A.; Giri, K.; Roy, S.; Ghosh, D.
10.1101/2023.10.16.562469 — genomics — Posted on 2023-10-17
2188 Phages Produce Persisters
Fernandez-Garcia, L.; Kirigo, J.; Huelgas-Mendez, D.; Tomas, M.; Garcia-Contreras, R.; Wood, T. K.
10.1101/2023.10.17.562728 — microbiology — Posted on 2023-10-17
2190 CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells
Oestreicher, D.; Chepurwar, S.; Kusch, K.; Rankovic, V.; Jung, S.; Strenzke, N.; Pangrsic, T.
10.1101/2023.10.16.562475 — neuroscience — Posted on 2023-10-17
2192 Non-canonical attractor dynamics underlie perceptual decision-making
Luo, T. Z.; Kim, T. D.; Gupta, D.; Bondy, A. G.; Kopec, C. D.; Elliott, V. A.; DePasquale, B.; Brody, C.
10.1101/2023.10.15.562427 — neuroscience — Posted on 2023-10-17
2194 Revisiting Hox gene evolution and Hox clusterlinkage across Nematoda
Kirangwa, J.; Laetsch, D. R.; King, E.; Stevens, L.; Blaxter, M.; Holovachov, O.; Schiffer, P.
10.1101/2023.10.16.562615 — developmental biology — Posted on 2023-10-17
2196 Modeling the roles of cohesotaxis, cell-intercalation, and tissue geometry in collective cell migration of Xenopus mesendoderm
Comlekoglu, T.; Dzamba, B. J.; Pacheco, G. G.; Shook, D. R.; Sego, T. J.; Glazier, J. A.; Peirce, S. M.; DeSimone, D. W.
10.1101/2023.10.16.562601 — developmental biology — Posted on 2023-10-17
2197 A comprehensive neuroanatomical survey of the Drosophila Lobula Plate Tangential Neurons with predictions for their optic flow sensitivity
Zhao, A.; Nern, A.; Koskela, S.; Dreher, M.; Erginkaya, M.; Laughland, C. W.; Ludwig, H. D.; Thomson, A. G.; Hoeller, J.; Parekh, R.; Romani, S.; Bock, D. D.; Chiappe, E.; Reiser, M. B.
10.1101/2023.10.16.562634 — neuroscience — Posted on 2023-10-17
2198 Identification of Evolutionarily Conserved VSX2 Enhancers in Retinal Development
Honnell, V.; Sweeney, S.; Norrie, J.; Ramirez, C.; Xu, B.; Teubner, B.; Lee, A. Y.; Bell, C.; Dyer, M. A.
10.1101/2023.10.17.562742 — developmental biology — Posted on 2023-10-17
2201 Fine-grained descending control of steering in walking Drosophila
Yang, H. H.; Brezovec, L. E.; Serratosa Capdevila, L.; Vanderbeck, Q. X.; Rayshubskiy, S.; Wilson, R. I.
10.1101/2023.10.15.562426 — neuroscience — Posted on 2023-10-17
2202 Analysis of a shark reveals ancient habenular asymmetries in gnathostomes and points to Wnt regulation as a driving force in their diversification
Lanoizelet, M.; Michel, L.; Lagadec, R.; Mayeur, H.; Guichard, L.; Severac, D.; Martin, K. J.; Klopp, C.; Marcellini, S.; Castillo, H.; Pollet, N.; Candal, E.; Debiais-Thibaud, M.; Boisvert, C.; Billoud, B.; Schubert, M.; Blader, P.; MAZAN, S.
10.1101/2023.10.17.562666 — developmental biology — Posted on 2023-10-17
2204 Mechanical coupling coordinates microtubule growth
Leeds, B. K.; Kostello, K. F.; Liu, Y. Y.; Nelson, C. R.; Biggins, S.; Asbury, C. L.
10.1101/2023.06.29.547092 — cell biology — Posted on 2023-10-17
2206 A single pair of pharyngeal neurons functions as a commander to reject high salt in Drosophila melanogaster
Sang, J.; Dhakal, S.; Shrestha, B.; Nath, D. K.; Kim, Y.; Ganguly, A.; Montell, C.; Lee, Y.
10.1101/2023.10.17.562703 — neuroscience — Posted on 2023-10-17
2207 Neutrophilia with damage to the blood-brain barrier and neurovascular unit following acute lung injury
Li, H.; Le, L.; Marrero, M. C.; David, J.; Caceres, A.; Lim, C.; Chiang, W.; Majewska, A.; Terrando, N.; Gelbard, H. A.
10.1101/2023.10.16.562508 — neuroscience — Posted on 2023-10-17
2209 Sibling chimerism among microglia in marmosets
del Rosario, R. C. H.; Krienen, F. M.; Zhang, Q.; Goldman, M.; Mello, C.; Lutservitz, A.; Ichihara, K.; Wysoker, A.; Nemesh, J.; Feng, G.; McCarroll, S. A.
10.1101/2023.10.16.562516 — neuroscience — Posted on 2023-10-17
2211 Cortical mapping of the sensory response reveals strong brain-state dependence of the late component
Montagni, E.; Resta, F.; Tort-Colet, N.; Scaglione, A.; Mazzamuto, G.; Destexhe, A.; Pavone, F. S.; Allegra Mascaro, A. L.
10.1101/2023.10.16.562034 — neuroscience — Posted on 2023-10-17
2212 MACROPHAGES COORDINATE IMMUNE RESPONSE TO LASER-INDUCED INJURY VIA EXTRACELLULAR TRAPS
Conedera, F. M.; Kokona, D.; Zinkernagel, M. S.; Stein, J. V.; Alt, C.; Enzmann, V.; Lin, C. P.
10.1101/2023.10.16.562553 — neuroscience — Posted on 2023-10-17
2213 Cell type specificity of mosaic chromosome 1q gain resolved by snRNA-seq in a case of epilepsy with hyaline protoplasmic astrocytopathy
Leng, K.; Titus, E.; Singhal, N.; Cadwell, C. R.; Devine, W. P.; Tihan, T.; Qi, Z.; Glenn, O.; Kamiya, S.; Berger, A.; Shieh, J.; Paredes, M.; Upadhyay, V.
10.1101/2023.10.16.562560 — neuroscience — Posted on 2023-10-17
2214 Age-related disparities in oscillatory dynamics within scene-selective regions during spatial navigation
Durteste, M.; Delaux, A.; Ariztegui, A.; Cottereau, B.; Sheynikhovich, D.; Ramanoël, S.; Arleo, A.
10.1101/2023.10.16.562507 — neuroscience — Posted on 2023-10-17
2215 Bridging the 3D geometrical organisation of white matter pathways across anatomical length scales and species
Kjer, M.; Andersson, M.; He, Y.; Pacureanu, A.; Daducci, A.; Pizzolato, M.; Salditt, T.; Robisch, A.-L.; Eckermann, M.; Töpperwien, M.; Dahl, A. B.; Elkjaer, M. L.; Illes, Z.; Ptito, M.; Andersen Dahl, V.; Dyrby, T. B.
10.1101/2023.10.16.562488 — neuroscience — Posted on 2023-10-17
2216 Immediate and Long-Term Electrophysiological Biomarkers of Antidepressant Behavioral Effects After Subanesthetic Ketamine and Medial Prefrontal Cortex Deep Brain Stimulation Treatment
Bergosh, M.; Medvidovic, S.; Zepeda, N. C.; Crown, L.; Ipe, J.; Debattista, L.; Romero, L.; Amjadi, E.; Lam, T.; Hakopian, E.; Choi, W.; Wu, K.; Lo, Y. T. J.; Lee, D. J.
10.1101/2023.10.13.562089 — neuroscience — Posted on 2023-10-17
2220 Regulation of pupil size in natural vision across the human lifespan
Lazar, R.; Degen, J.; Fiechter, A.-S.; Monticelli, A.; Spitschan, M.
10.1101/2023.10.16.562484 — neuroscience — Posted on 2023-10-17
2221 Developmental pyrethroid exposure disrupts folate metabolism in mouse brain
Curtis, M. A.; Saferin, N.; Nguyen, J. H.; Imami, A. S.; Neifer, K. L.; Miller, G. W.; Burkett, J. P.
10.1101/2023.10.13.562226 — neuroscience — Posted on 2023-10-17
2223 CD1d-dependent neuroinflammation impairs tissue repair and functional recovery following a spinal cord injury
Wu, X.; Liu, J.; Li, W.; Khan, M. F.; Dai, H.; Tian, J.; Priya, R.; Tian, D. J.; Wu, W.; Yaacoub, A. P.; Gu, J.; Syed, F.; Yu, C. H.; Gao, X.; Yu, Q.; Xu, X.-M.; Brutkiewicz, R. R.
10.1101/2023.10.13.562047 — neuroscience — Posted on 2023-10-17
2224 White Matter Correlates of Impulsive Behavior in Healthy Individuals: A Diffusion MRI Study
Rashidi, F.; Parsaei, M.; Kiani, I.; Sadri, A.; Aarabi, M. H.; Darijani, S. R.; Lee, Y. S.; Sanjari Moghaddam, H.
10.1101/2023.10.14.562328 — neuroscience — Posted on 2023-10-17
2225 Binge Feeding Promotes Appetite via Modulating Olfactory Flavor Representation
Lo, H.; Tantirigama, M. L. S.; Schoenherr, A.; Moreno-Velasquez, L.; Faiss, L.; Rost, B. R.; Larkum, M. E.; Judkewitz, B.; Stumpenhorst, K.; Rivalan, M.; Winter, Y.; Schmitz, D.; Johenning, F. W.
10.1101/2023.10.17.562714 — neuroscience — Posted on 2023-10-17
2229 Microglia are dispensable for experience-dependent refinement of visual circuitry
Brown, T. C.; Crouse, E. C.; Attaway, C. A.; Oakes, D. K.; Minton, S. W.; Borghuis, B. G.; McGee, A. W.
10.1101/2023.10.17.562708 — neuroscience — Posted on 2023-10-17
2230 Accelerated Aging after Traumatic Brain Injury: an ENIGMA Multi-Cohort Mega-Analysis
Dennis, E. L.; Vervoordt, S.; Adamson, M. M.; Amiri, H.; Bigler, E.; Caeyenberghs, K.; Cole, J. H.; Dams-O'Connor, K.; Deutscher, E. M.; Dobryakova, E.; Genova, H. M.; Grafman, J. H.; Haberg, A. K.; Hellstrom, T.; Irimia, A.; Koliatsos, V. E.; Lindsey, H. M.; Livny, A.; Menon, D. K.; Merkley, T. L.; Mohamed, A. Z.; Mondello, S.; Monti, M. M.; Newcombe, V. F.; Newsome, M. R.; Ponsford, J.; Smevik, H.; Spitz, G.; Westlye, L. T.; Zafonte, R.; Thompson, P. M.; Wilde, E. A.; Olsen, A.; Hillary, F. G.
10.1101/2023.10.16.562638 — neuroscience — Posted on 2023-10-17
2236 Emergent effects of synaptic connectivity on cortical sleep slow wave amplitude, density and propagation in a large-scale thalamocortical network model of the human brain
Marsh, B.; Zuloaga, M. G. N.; Rosen, B. Q.; Sokolov, Y.; Delanois, J. E.; Gonzalez, O. C.; Krishnan, G. P.; Halgren, E.; Bazhenov, M.
10.1101/2023.10.15.562408 — neuroscience — Posted on 2023-10-17
2242 Caller identification and characterization of individual humpback whale acoustic behavior
Zeh, J. M.; Perez-Marrufo, V.; Adcock, D. L.; Jensen, F. H.; Knapp, K. J.; Robbins, J.; Tackaberry, J. E.; Weinrich, M.; Friedlaender, A. S.; Wiley, D. N.; Parks, S. E.
10.1101/2023.10.17.562793 — animal behavior and cognition — Posted on 2023-10-17
2244 Keratinocytes Drive the Epithelial Hyperplasia Key to Sea Lice Resistance in Coho Salmon
Salisbury, S. J.; Ruiz Daniels, R.; Monaghan, S. J.; Bron, J. E.; Villamayor, P. R.; Gervais, O.; Fast, M. D.; Sveen, L.; Houston, R. D.; Robinson, N.; Robledo, D.
10.1101/2023.10.15.562030 — genomics — Posted on 2023-10-17
2245 Dynamic Hippo pathway activity underlies mesenchymal differentiation during lung alveolar morphogenesis
Chaudhry, F. N.; Michki, N. S.; Shirmer, D. L.; Mcgrath-Morrow, S.; Young, L. R.; Frank, D. B.; Zepp, J. A.
10.1101/2023.10.17.561252 — developmental biology — Posted on 2023-10-17
2246 3D RNA profile of habenulae in the catshark Scyliorhinus canicula: a reference in jawed vertebrates
Michel, L.; Mayeur, H.; Quillien, A.; Heier, N.; Clairet, J.; Dejean, S.; Blader, P.; Lagadec, R.; Mazan, S.
10.1101/2023.10.17.562684 — developmental biology — Posted on 2023-10-17
2248 PBRM-1/PBAF-regulated genes in a multipotent progenitor
Mathies, L. D.; Soukup, E. M.; Kim, A. C.; Thomas, A. E.; Bettinger, J. C.
10.1101/2023.10.16.562537 — developmental biology — Posted on 2023-10-17
2259 MADAME: a user-friendly bioinformatic tool for data and metadata retrieval in microbiome research
Fumagalli, S.; Soletta, G.; Agostinetto, G.; Striani, M.; Labra, M.; Casiraghi, M.; Bruno, A.
10.1101/2023.10.14.562335 — bioinformatics — Posted on 2023-10-17
2260 Assessing the potential for genome-assisted breeding in red perilla using quantitative trait locus analysis and genomic prediction
Kinoshita, S.; Sakurai, K.; Hamazaki, K.; Tsusaka, T.; Sakurai, M.; Kurosawa, T.; Aoki, Y.; Shirasawa, K.; Isobe, S.; Iwata, H.
10.1101/2023.10.15.560967 — genomics — Posted on 2023-10-17
2263 Toxoplasma gondii and Trypanosoma lewisi infection in urban small mammals from Cotonou, Benin, with special emphasis on co-infection patterns
ETOUGBETCHE, J. R.; HOUEMENOU, G.; Missihoun, A. A.; Gauthier, P.; Dossou, H.-J.; Galal, L.; Dalecky, A.; Diagne, C.; Dobigny, G.; MERCIER, A.
10.1101/2023.10.15.558972 — ecology — Posted on 2023-10-17
2268 Bile acid fitness determinants of a Bacteroides fragilis isolate from a human pouchitis patient
Fiebig, A.; Schnizlein, M.; Pena-Rivera, S.; Trigodet, F.; Dubey, A.; Hennessy, M.; Basu, A.; Pott, S.; Dalal, S.; Rubin, D.; Sogin, M.; Eren, A. M.; Chang, E.; Crosson, S.
10.1101/2023.05.11.540287 — microbiology — Posted on 2023-10-17
2269 Design of universal Ebola virus vaccine candidates via immunofocusing
Xu, D.; Powell, A. E.; Utz, A.; Sanyal, M.; Do, J.; Patten, J. J.; Moliva, J. I.; Sullivan, N. J.; Davey, R. A.; Kim, P. S.
10.1101/2023.10.14.562364 — immunology — Posted on 2023-10-17
2271 hkb is required for DIP-α expression and target recognition in the Drosophila neuromuscular circuit
Carrillo, R. A.; Wang, Y.; Salazar, R.; Simonetta, L.; Sorrentino, V.; Gatton, T. J.; Wu, B.; Vecsey, C. G.
10.1101/2023.10.15.562341 — neuroscience — Posted on 2023-10-17
2273 ECM-Focused Proteomic Analysis of Ear Punch Regeneration in Acomys cahirinus
McCabe, M. C.; Okamura, D. M.; Erickson, C. B.; Perry, B. W.; Brewer, C. M.; Nguyen, E. D.; Saviola, A. J.; Majesky, M. W.; Hansen, K. C.
10.1101/2023.10.11.561940 — molecular biology — Posted on 2023-10-17
2274 Lipid discovery enabled by sequence statistics and machine learning
Christensen, P. M.; Martin, J.; Uppuluri, A.; Joyce, L. R.; Wei, Y.; Guan, Z.; Morcos, F.; Palmer, K.
10.1101/2023.10.12.562061 — microbiology — Posted on 2023-10-17
2278 Automatic cell type harmonization and integration across Human Cell Atlas datasets
Xu, C.; Prete, M.; Webb, S.; Jardine, L.; Stewart, B.; Hoo, R.; He, P.; Meyer, K. B.; Teichmann, S.
10.1101/2023.05.01.538994 — bioinformatics — Posted on 2023-10-17
2280 Circular RNA profiling identifies circ5078 as a BMPR2-derived regulator of endothelial translation
VandenBroek, M. M.; Sharp, M. C.; Thompson, P.; Fagbola, E.; Quilty, D.; Mewburn, J. D.; Theilmann, A. L.; Archer, S. L.; Renwick, N.; Ormiston, M. L.
10.1101/2023.09.18.556866 — molecular biology — Posted on 2023-10-17
2281 Automated model building and protein identification in cryo-EM maps
Jamali, K.; Kall, L.; Zhang, R.; Brown, A.; Kimanius, D.; Scheres, S.
10.1101/2023.05.16.541002 — molecular biology — Posted on 2023-10-17
2282 Resistance exercise protects mice from protein-induced fat accretion
Trautman, M. E.; Braucher, L. N.; Elliehausen, C.; Zhu, W. G.; Zelenovskiy, E.; Green, M.; Sonsalla, M. M.; Yeh, C.-Y.; Hornberger, T. A.; Konopka, A. R.; Lamming, D. W.
10.1101/2022.10.18.512689 — physiology — Posted on 2023-10-17
2283 Convergent alterations in the tumor microenvironment of MYC-driven human and murine prostate cancer
Graham, M. K.; Wang, R.; Chikarmane, R.; Wodu, B.; Vaghasia, A.; Gupta, A.; Zheng, Q.; Hicks, J.; Sysa-Shah, P.; Pan, X.; Castagna, N.; Liu, J.; Meyers, J.; Skaist, A.; Zhang, Y.; Schuebel, K.; Simons, B.; Bieberich, C. J.; Nelson, W.; Lupold, S. E.; DeWeese, T. L.; De Marzo, A. M.; Yegnasubramanian, S.
10.1101/2023.09.07.553268 — cancer biology — Posted on 2023-10-17
2285 Aberrant landscapes of maternal meiotic crossovers contribute to aneuploidies in human embryos
Ariad, D.; Madjunkova, S.; Madjunkov, M.; Chen, S.; Abramov, R.; Librach, C.; McCoy, R. C.
10.1101/2023.06.07.543910 — genomics — Posted on 2023-10-17
2286 Early Neolithic forest farming at Seven Springs, Martlesham, Suffolk inferred from sedaDNA and pollen
Hudson, S. M.; Allen, S. J.; Alsos, I. G.; Curl, J.; Heintzman, P. D.; Hughes, P.; Gardiner, L.; Lloyd-Smith, L.; Pears, B. R.; Scaife, R.; Stoof-Leichsenring, K. R.; Brown, A.
10.1101/2023.10.11.561859 — ecology — Posted on 2023-10-17
2289 Combined studies of N170/M170 responses to single letters and pseudoletters
Toussi, N.; Takai, O.; Bann, S.; Rowe, J.; Hildebrand, A.-J.; Herdman, A.
10.1101/2023.10.13.562197 — neuroscience — Posted on 2023-10-17
2290 Amelioration of Functional and Histopathological Consequences after Spinal Cord Injury through Phosphodiesterase 4D (PDE4D) Inhibition
Schepers, M.; Hendrix, S.; Mussen, F.; Van Breedam, E.; Ponsaerts, P.; Lemmens, S.; Hellings, N.; Ricciarelli, R.; Fedele, E.; Bruno, O.; Brullo, C.; Prickaerts, J.; Van Broeckhoven, J.; Vanmierlo, T.
10.1101/2023.10.13.562181 — neuroscience — Posted on 2023-10-17
2294 Pangenome graph layout by Path-Guided Stochastic Gradient Descent
Heumos, S.; Guarracino, A.; Schmelzle, J.-N. M.; Li, J.; Zhang, Z.; Hagmann, J.; Nahnsen, S.; Prins, P.; Garrison, E.
10.1101/2023.09.22.558964 — bioinformatics — Posted on 2023-10-17
2295 Detecting significantly recurrent genomic connections from simple and complex rearrangements in the cancer genome
Zhang, S.; Kumar, K. H.; Shapira, O.; Yao, X.; Wala, J.; Dubois, F.; Gold, R.; Haber, J. E.; Cherniack, A.; Imielinski, M.; Dalin, S.; Beroukhim, R.
10.1101/2023.10.13.561748 — genomics — Posted on 2023-10-17
2300 Increased epithelial mTORC1 activity in chronic rhinosinusitis with nasal polyps
Barrett, N. A.; Huang, G. X.; Hallen, N. R.; Lee, M.; Zheng, K.; Wang, X.; Mandanas, M. V.; Djeddi, S.; Fernandez, D.; Hacker, J.; Ryan, T.; Bergmark, R. W.; Bhattacharyya, N.; Lee, S.; Maxfield, A. Z.; Roditi, R. E.; Buchheit, K. M.; Laidlaw, T. M.; Gern, J. E.; Hallstrand, T. S.; Ray, A.; Wenzel, S. E.; Boyce, J. A.; Gutierrez-Arcelus, M.
10.1101/2023.10.13.562288 — immunology — Posted on 2023-10-17
2308 Dual Ethanolamine Head Groups in Ionizable Lipids Facilitate Phospholipid-free Stable Nanoparticle Formulation for Augmented and Safer mRNA Delivery
Lu, J.; Jiang, T.; Li, X.; Tan, S.; Zhang, Y.; Gu, H.; Chen, L.; Guo, J.; Yu, R.; Zang, J.; Ouyang, D.; Yu, H.; Yao, H.; Qiu, M.; Lin, J.
10.1101/2023.10.13.562139 — bioengineering — Posted on 2023-10-17
2309 Osteochondral fluid transport in an ex vivo system
Hislop, B. D.; Mercer, A. K.; Whitley, A. G.; Meyers, E. P.; Heveran, C. M.; June, R. K.
10.1101/2023.10.13.562188 — bioengineering — Posted on 2023-10-17
2313 A natural bacterial pathogen of C. elegans uses a small RNA to induce transgenerational inheritance of learned avoidance
Sengupta, T.; Ange, J. S.; Moore, R. S.; Kaletsky, R. T.; Marogi, J. T.; Myhrvold, C.; Gitai, Z.; Murphy, C. T.
10.1101/2023.07.20.549962 — genetics — Posted on 2023-10-17
2314 Pervasive biases in proxy GWAS based on parental history of Alzheimer's disease
Wu, Y.; Sun, Z.; Zheng, Q.; Miao, J.; Dorn, S.; Mukherjee, S.; Fletcher, J.; Lu, Q.
10.1101/2023.10.13.562272 — genetics — Posted on 2023-10-17
2319 Antigen-level resolution of commensal-specific B cell responses enabled by phage-display screening and B cell tetramers
Verma, S.; Dufort, M. J.; Olsen, T. M.; Labuda, J. C.; Kimmel, S.; Scharffenberger, S.; McGuire, A.; Harrison, O. J.
10.1101/2023.10.13.562275 — immunology — Posted on 2023-10-17
2321 HP1 deficiency results in De-Repression of Endogenous Retroviruses and Induction of Neurodegeneration via Complement
Newman, A. G.; Sharif, J.; Bessa, P.; Zaqout, S.; Brown, J.; Dannenberg, R.; Nakayama, M.; Mueller, S.; Schaub, T.; Manickaraj, S.; Böhm-Sturm, P.; Ohara, O.; Koseki, H.; Singh, P. B.; Tarabykin, V.
10.1101/2022.08.29.505641 — neuroscience — Posted on 2023-10-17
2324 Long chain monomethyl branched-chain fatty acid levels in human milk vary with gestational weight gain
O'Sullivan, A.; Brady, E.; Lafferty, L.; O'Shea, F.; O'Regan, Z.; Meurs, N.; Baldini, M.; Gengatharan, J.; Metallo, C. M.; Wallace, M.
10.1101/2023.10.13.561203 — physiology — Posted on 2023-10-17
2325 Breast cancer cells can recognize and respond to different levels of progestins to achieve different phenotypic outputs
Dolan, E. L.; Safi, R.; Chang, C.-Y.; Eaton, H. E.; Krishnan, S.; Safi, R.; Watkinson, P.; Long, H.; Xie, Y.; Brown, M.; Murphy, S. K.; McDonnell, D. P.
10.1101/2023.10.13.562206 — cancer biology — Posted on 2023-10-17
2326 Single cell transcriptomic profiling identifies tumor-acquired and therapy-resistant cell states in pediatric rhabdomyosarcoma
Danielli, S. G.; Wei, Y.; Dyer, M. A.; Stewart, E.; Wachtel, M.; Schaefer, B. W.; Patel, A. G.; Langenau, D. M.
10.1101/2023.10.13.562224 — cancer biology — Posted on 2023-10-17
2329 Active regulatory elements recruit cohesin to establish cell-specific chromatin domains.
Georgiades, E.; Harrold, C. L.; Roberts, N.; Kassouf, M.; Riva, S. G.; Sanders, E. L.; Francis, H. S.; Blayney, J.; Oudelaar, M.; Milne, T. A.; Higgs, D.; Hughes, J. R.
10.1101/2023.10.13.562171 — genomics — Posted on 2023-10-17
2330 Cross-sector collaboration reduces SARS-CoV-2 risk in deer
Cook, J. D.; Rosenblatt, E.; DiRenzo, G. V.; Campbell Grant, E. H.; Mosher, B.; Arce, F.; Christensen, S.; Ghai, R.; Runge, M.
10.1101/2023.10.13.562192 — ecology — Posted on 2023-10-17
2331 Valuing carbon sequestration by Antarctic krill faecal pellets
Cavan, E. L.; Mackay, N.; Hill, S.; Atkinson, A.; Belcher, A.; Visser, A.
10.1101/2023.10.13.562177 — ecology — Posted on 2023-10-17
2333 The Distal-Proximal Relationships Among the Human Moonlighting Proteins: Evolutionary hotspots and Darwinian checkpoints
Nawn, D.; Hassan, S. S.; Sil, M.; Ghosh, A.; Goswami, A.; Basu, P.; W. Dayhoff, G.; Lundstrom, K.; Uversky, V. N.
10.1101/2023.10.12.562146 — genomics — Posted on 2023-10-17
2335 Deep convolutional and conditional neural networks for large-scale genomic data generation
Yelmen, B.; Decelle, A.; Boulos, L. L.; Szatkownik, A.; Furtlehner, C.; Charpiat, G.; Jay, F.
10.1101/2023.03.07.530442 — genomics — Posted on 2023-10-17
2343 Metabolic bypass rescues aberrant S-nitrosylation-induced TCA cycle inhibition and synapse loss in Alzheimer's disease human neurons
Andreyev, A. Y.; Yang, H.; Doulias, P.-T.; Dolatabadi, N.; Zhang, X.; Luevanos, M.; Blanco, M.; Baal, C.; Putra, I.; Nakamura, T.; Ischiropoulos, H.; Tannenbaum, S. R.; Lipton, S. A.
10.1101/2023.10.12.562118 — neuroscience — Posted on 2023-10-17
2357 LSD1 controls a nuclear checkpoint in Wnt/β-catenin signaling to regulate muscle stem cell self renewal
Mouradian, S.; Cicciarello, D.; Lacoste, N.; Risson, V.; Berretta, F.; Le Grand, F.; Rose, N.; Simonet, T.; Schaeffer, L.; Scionti, I.
10.1101/2022.06.10.495614 — developmental biology — Posted on 2023-10-17
2358 Plakins are involved in the maintenance of epithelial polarity
Geay, J.; Margaron, Y.; Gentien, D.; Reyal, F.; Puisieux, A.; Blanchoin, L.; Guyon, L.; Thery, M.
10.1101/2023.10.16.562500 — cell biology — Posted on 2023-10-17
2366 On metallic luster and iridescence in animal coloration
Norden, K. K.; Steiner, R. S.; Stephenson, A. B.; Stoddard, M. C.
10.1101/2023.10.12.562066 — evolutionary biology — Posted on 2023-10-17
2368 Aminoglycoside heteroresistance in Enterobacter cloacae is driven by the cell envelope stress response.
Choi, A. J.; Bennison, D. J.; Kulkarni, E.; Sun, H.; Li, H.; Bradshaw, J.; Yeap, H. W.; Lim, N.; Mishra, V.; Crespo-Puig, A.; Davies, F.; Sriskandan, S.; Shenoy, A. R.
10.1101/2023.10.11.561937 — microbiology — Posted on 2023-10-17
2369 The R1441C-LRRK2 mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner
Wallings, R.; McFarland, K.; Staley, H.; Neighbarger, N.; Schaake, S.; Brueggemann, N.; Zittel, S.; Usnich, T.; Klein, C.; Sammler, E.; Tansey, M. G.
10.1101/2023.10.12.562063 — immunology — Posted on 2023-10-17
2374 Medicago truncatula SOBIR1 controls specificity in the Rhizobium-legume symbiosis
Sarrette, B.; Luu, T.-B.; Johansson, A.; Fliegmann, J.; Pouzet, C.; Le Ru, A.; Pichereaux, C.; Rembliere, C.; Sauviac, L.; Carles, N.; Amblard, E.; Guyot, V.; Bonhomme, M.; Cullimore, J.; Gough, C.; Jacquet, C.; Pauly, N.
10.1101/2023.10.15.561875 — plant biology — Posted on 2023-10-17
2376 Rapid propagation of Ca2+ waves and electrical signals in a liverwort Marchantia polymorpha
Watanabe, K.; Hashimoto, K.; Hasegawa, K.; Shindo, H.; Kupisz, K.; Koselski, M.; Wasko, P.; Trebacz, K.; Kuchitsu, K.
10.1101/2023.10.16.562169 — plant biology — Posted on 2023-10-17
2378 Regulated Cleavage and Relocation of FERONIA Control Immunity in Arabidopsis Roots
Yu, F.; Chen, J.; Qiang, X.; Liu, H.; Xu, F.; Wang, L.; Jiang, L.; Li, C.; Wang, B.; Luan, S.; Wu, D.; Zhou, F.
10.1101/2023.10.16.562456 — plant biology — Posted on 2023-10-17
2382 Low exposure to lithium does not induce nephrogenic diabetes insipidus but microcystic dilations of collecting ducts in a long-term rat model
Tabibzadeh, N.; Klein, M.; Try, M.; Poupon, J.; Houillier, P.; Klein, C.; Cheval, L.; Crambert, G.; Lasaad, S.; Chevillard, L.; Megarbane, B.
10.1101/2023.10.12.562078 — pharmacology and toxicology — Posted on 2023-10-17
2386 A morphogenic cascade emerges from the co-evolution of spheroid fluidization and fracturing of multicellular barriers
Wu, S. K.; Ho, C. Z.; Sun, F.; Lou, Y.; Huang, C. B.-X.; Xiao, J.; Shagirov, M.; Yow, I.; Chin, J. F. L.; Verma, S.; Yap, A.; Lin, Y.; Hiraiwa, T.; Low, B. C.
10.1101/2023.09.25.559247 — cell biology — Posted on 2023-10-17
2389 Dynamic changes in subplate and cortical plate microstructure precede the onset of cortical folding in vivo
Wilson, S.; Christiaens, D.; Yun, H.; Uus, A.; Cordero-Grande, L.; Karolis, V.; Price, A.; Deprez, M.; Tournier, J.-D.; Rutherford, M.; Grant, E.; Hajnal, J. V.; Edwards, A. D.; O'Muircheartaigh, J.; Arichi, T.; Im, K.
10.1101/2023.10.16.562524 — neuroscience — Posted on 2023-10-17
2391 Long-term tracking of social structure in groups of rats
Nagy, M.; Davidson, J. D.; Vasarhelyi, G.; Abel, D.; Kubinyi, E.; El Hady, A.; Vicsek, T.
10.1101/2023.03.18.533183 — animal behavior and cognition — Posted on 2023-10-17
2395 Rapid intracellular acidification is a novel plant defense response countered by the brown planthopper
Jiang, Y.; Zhang, X.-Y.; Li, S.; Xie, Y.-C.; Yang, Y.; Pu, Z.; Zhang, L.; Lu, J.-B.; Huang, H.-J.; Zhang, C.-X.; He, S. Y.
10.1101/2023.05.24.542203 — plant biology — Posted on 2023-10-16
2397 Hyaluronic acid turnover controls the severity of Cerebral Cavernous Malformations in bioengineered human micro-vessels
Yordanov, T. E.; Martinez, M. A. E.; Esposito, T.; Tefft, J. B.; Labzin, L. I.; Stehbens, S. J.; Rowan, A.; Hogan, B. M.; Chen, C. S.; Lauko, J.; Lagendijk, A. K.
10.1101/2023.03.27.534302 — cell biology — Posted on 2023-10-16
2398 Dissociable contributions of basolateral amygdala and ventrolateral orbitofrontal cortex to flexible learning under uncertainty
Aguirre, C. G.; Woo, J. H.; Romero-Sosa, J.-L.; Rivera, Z. M.; Tejada, A. N.; Munier, J. J.; Perez, J.; Goldfarb, M.; Das, K.; Gomez, M.; Ye, T.; Pannu, J.; Evans, K.; O'Neill, P. R.; Spigelman, I.; Soltani, A.; Izquierdo, A.
10.1101/2023.04.03.535471 — neuroscience — Posted on 2023-10-16
2399 Effectiveness of heat tolerance rice cultivars in preserving grain appearance quality under high temperatures - A meta-analysis
Wakatsuki, H.; Takimoto, T.; Ishigooka, Y.; Nishimori, M.; Sakata, M.; Saida, N.; Akagi, K.; Makowski, D.; Hasegawa, T.
10.1101/2023.03.09.531821 — plant biology — Posted on 2023-10-16
2401 Dimension Reduction by Spatial Components Analysis Improves Pattern Detection in Multivariate Spatial Data
Kleinenkuhnen, N.; Koehler, D.; Baar, T.; Nikopoulou, C.; Kondylis, V.; Schmid, M.; Tessarz, P.; Tresch, A.
10.1101/2023.10.12.562016 — bioinformatics — Posted on 2023-10-16
2402 Model discovery approach enables non-invasive measurement of intra-tumoral fluid transport in dynamic MRI
Woodall, R. T.; Esparza, C. C.; Gutova, M.; Wang, M.; Cunningham-Reynolds, J.; Brummer, A. B.; Stine, C.; Brown, C.; Munson, J. M.; Rockne, R. C.
10.1101/2023.08.28.554919 — bioengineering — Posted on 2023-10-16
2405 Ant identity determines the fungi richness and composition of a myrmecochorous seed
Fernandes, T. V.; Fernandes, O. L.; Gomes, I. J. M. T.; Solar, R. R. C.; Campos, R. I.
10.1101/2023.10.12.562019 — ecology — Posted on 2023-10-16
2406 The Interferon-inducible NAMPT acts as a protein phosphoribosylase to restrict viral infection
Feng, S.; Xie, N.; Liu, Y.; Qin, C.; Savas, A. C.; Wang, T.-y.; Li, S.; Rao, Y.; Shambayate, A.; Chou, T.-f.; Brenner, C.; Huang, C.; Feng, P.
10.1101/2023.10.12.562112 — molecular biology — Posted on 2023-10-16
2408 Microbial communities from lean or obese are differently shaped after apple fibres supplementation
Dell'Olio, A.; Scott, W.; Taroncher-Ferrer, S.; San Onofre, N.; Soriano, J.; Rubert, J.
10.1101/2023.10.16.562478 — microbiology — Posted on 2023-10-16
2409 Comprehensive Identification of Pathogenic Microbes and Antimicrobial Resistance Genes in Food Products Using Nanopore Sequencing-Based Metagenomics
Lee, A. W.-T.; NG, I. C.-F.; WONG, E. Y.-K.; WONG, I. T.-F.; SZE, R. P.-P.; CHAN, K.-Y.; SO, T.-Y.; ZHANG, Z.; FUNG, S. K.-Y.; WONG, S. C.-Y.; TAM, W.-Y.; Lao, H.-Y.; LEE, L.-K.; LEUNG, J. S.-L.; CHAN, C. T.-M.; NG, T. T.-L.; CHOW, F. W.-N.; LEUNG, P. H.-M.; SIU, G. K.-H.
10.1101/2023.10.15.562131 — microbiology — Posted on 2023-10-16
2410 Physiological characterization of single gene lysis proteins
Antillon, S. F.; Bernhardt, T.; Chamakura, K. R.; Young, R. F.
10.1101/2023.10.16.562596 — microbiology — Posted on 2023-10-16
2414 PhysioFit: a software to quantify cell growth parameters and extracellular fluxes
Le Gregam, L.; Guitton, Y.; Bellvert, F.; Heux, S.; Jourdan, F.; Portais, J.-C.; Millard, P.
10.1101/2023.10.12.561695 — bioinformatics — Posted on 2023-10-16
2415 Culture system for longitudinal monitoring of bone remodeling ex vivo
Cramer, E. E. A.; Hermsen, K. C. J.; Kock, L. M.; Ito, K.; Hofmann, S.
10.1101/2023.10.12.562045 — bioengineering — Posted on 2023-10-16
2416 Engineering Regionally-Activated Drugs for Neuroscience
Huang, Z.; Mitrofan, A.; Nouraein, S.; Horak, C.; Seo, J. P.; Harb, M.; Jin, R.; Szablowski, J. O.
10.1101/2023.10.12.562069 — bioengineering — Posted on 2023-10-16
2417 Endocisternal interfaces for minimally invasive neural stimulation and recording of the brain and spinal cord
Chen, J. C.; Dhuliyawalla, A.; Garcia, R.; Robledo, A.; Woods, J. E.; Alrashdan, F.; O'Leary, S.; Crosby, S.; Felicella, M. M.; Wakhloo, A. K.; Karas, P.; Goodman, W.; Sheth, S. A.; Sheth, S. A.; Robinson, J.; Kan, P.
10.1101/2023.10.12.562145 — bioengineering — Posted on 2023-10-16
2418 Trifunctional sphinganine: a new tool to dissect sphingolipid function
Farley, S. E.; Stein, F.; Haberkant, P.; Tafesse, F. G.; Schultz, C.
10.1101/2023.10.16.562528 — biochemistry — Posted on 2023-10-16
2420 X-Ray Structure and enzymatic study of a Bacterial NADPHoxidase highlight the activation mechanism of eukaryoticNOX
Petit-Hartlein, I.; Vermot, A.; Thepaut, M.; Humm, A.-S.; Dupeux, F.; Dupuy, J.; Chaptal, V.; Marquez, J. A.; Smith, S. M. E.; Fieschi, F.
10.1101/2023.10.16.562591 — biochemistry — Posted on 2023-10-16
2422 New Interactive Machine Learning Tool for Marine Image Analysis
Clark, H. P.; Smith, A. G.; McKay Fletcher, D.; Larsson, A. I.; Jaspars, M.; De Clippele, L. H.
10.1101/2023.10.12.562046 — ecology — Posted on 2023-10-16
2424 DSIF factor Spt5 coordinates transcription, maturation and exoribonucleolysis of RNA polymerase II transcripts.
Kus, K.; Carrique, L.; Kecman, T.; Fournier, M.; Hassanein, S. S.; Aydin, E.; Kilchert, C.; Grimes, J. M.; Vasiljeva, L.
10.1101/2023.10.16.562519 — molecular biology — Posted on 2023-10-16
2426 Chronic Interferon Stimulated Gene Transcription Promotes Oncogene Induced Breast Cancer
Wang, H.; Canasto-Chibuque, C.; Kim, J. H.; Hohl, M.; Leslie, C.; Reis-Filho, J. S.; Petrini, J. H.
10.1101/2023.10.16.562529 — molecular biology — Posted on 2023-10-16
2428 Hundreds of antimicrobial peptides create a selective barrier for insect gut symbionts
Lachat, J.; Lextrait, G.; Jouan, R.; Boukherissa, A.; Yokota, A.; Jang, S.; Ishigami, K.; Futahashi, R.; Cossard, R.; Naquin, D.; Costache, V.; Augusto, L.; Tissiere, P.; Biondi, E. G.; Alunni, B.; Timchenko, T.; Ohbayashi, T.; Kikuchi, Y.; Mergaert, P.
10.1101/2023.10.16.562546 — microbiology — Posted on 2023-10-16
2429 Widespread B-vitamin auxotrophy in marine particle-associated bacteria
Gregor, R.; Szabo, R. E.; Vercelli, G. T.; Gralka, M.; Reynolds, R.; Qu, E. B.; Levine, N. M.; Cordero, O. X.
10.1101/2023.10.16.562604 — microbiology — Posted on 2023-10-16
2430 Prevalence and diversity of TAL effector-like proteins in fungal endosymbiotic Mycetohabitans spp.
Carpenter, S. C. D.; Bogdanove, A. J.; Stajich, J. E.; Uehling, J.; Lovett, B.; Kasson, M.; Carter, M. E.
10.1101/2023.10.16.562584 — microbiology — Posted on 2023-10-16
2431 Enterocytozoon hepatopenaei Proliferate in Procambarus clarkii: A Warning for Crayfish and Shrimp Aquaculture
Ling, b.; Wu, Y.; Yu, Q.; Wang, C.; Hu, M.; Meng, X.; Long, M.; Pan, G.; Xiang, Z.; Zhou, Z.; Chen, J.
10.1101/2023.10.15.561606 — microbiology — Posted on 2023-10-16
2433 A Tetravalent Dengue Virus-like Particle Vaccine Induces High levels of Neutralizing Antibodies and Inhibits Dengue Replication in Non-Human Primates
Thoresen, D.; Matsuda, K.; Urakami, A.; Ngwe Tun, M. M.; Nomura, T.; Moi, M. L.; Watanabe, Y.; Ishikawa, M.; Hau, T. T. T.; Yamamoto, H.; Suzaki, Y.; Ami, Y.; Smith, J. F.; Matano, T.; Morita, K.; akahata, W.
10.1101/2023.10.16.562563 — microbiology — Posted on 2023-10-16
2435 Transertion and cell geometry organize the Escherichia coli nucleoid during rapid growth
Spahn, C.; Middlemiss, S.; Gomez-de-Mariscal, E.; Henriques, R.; Bode, H. B.; Holden, S.; Heilemann, M.
10.1101/2023.10.16.562172 — microbiology — Posted on 2023-10-16
2437 The PDIM paradox of Mycobacterium tuberculosis: new solutions to a persistent problem
Mulholland, C. V.; Wiggins, T. J.; Cui, J.; Vilcheze, C.; Rajagopalan, S.; Shultis, M. W.; Reyes-Fernandez, E. Z.; Jacobs, W. R.; Berney, M.
10.1101/2023.10.16.562559 — microbiology — Posted on 2023-10-16
2438 An inducible ESCRT-III inhibition tool to control HIV-1 budding
Wang, H.; Gallet, B.; Moriscot, C.; Pezet, M.; Chatellard, C.; Kleman, J.-P.; Gottlinger, H.; Weissenhorn, W.; Boscheron, C.
10.1101/2023.10.16.562494 — microbiology — Posted on 2023-10-16
2439 Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt
Erice, P. A.; Huang, X.; Seasock, M. J.; Robertson, M. J.; Tung, H.-Y.; Perez-Negron, M. A.; Lotlikar, S. L.; Corry, D.; Kheradmand, F.; Rodriguez, A.
10.1101/2023.10.12.562059 — immunology — Posted on 2023-10-16
2443 Defective lysosomal acidification contributes to TNFR1 mediated neuronal necroptosis in Alzheimer's disease
Lo, C. H.; Zeng, J.; Loi, G. W. Z.; Saipuljumri, E. N.; O'Connor, L. M.; Indajang, J.; Reynolds, R.; Barron, A. M.
10.1101/2023.10.12.562041 — neuroscience — Posted on 2023-10-16
2446 V-pipe 3.0: a sustainable pipeline for within-sample viral genetic diversity estimation
Fuhrmann, L.; Jablonski, K. P.; Topolsky, I.; Batavia, A. A.; Borgsmueller, N.; Icer Baykal, P.; Carrara, M.; Chen, C.; Dondi, A.; Dragan, M.; Dreifuss, D.; John, A.; Langer, B.; Okoniewski, M.; du Plessis, L.; Schmitt, U.; Singer, F.; Stadler, T.; Beerenwinkel, N.
10.1101/2023.10.16.562462 — bioinformatics — Posted on 2023-10-16
2449 STING induces LUBAC-mediated synthesis of linear ubiquitin chains to stimulate innate immune signaling
Fischer, T. D.; Bunker, E. N.; Zhu, P.-P.; Le Guerroue, F.; Dominguez-Martin, E.; Scavone, F.; Cohen, R. E.; Yao, T.; Wang, Y.; Werner, A.; Youle, R. J.
10.1101/2023.10.14.562349 — cell biology — Posted on 2023-10-16
2451 Protein Kinase Structure and Dynamics: Role of the αC-β4 Loop
Wu, J.; Jonniya, N. A.; Hirakis, S. P.; Olivieri, C.; Veglia, G.; Kornev, A. P.; Taylor, S. S.
10.1101/2023.08.31.555822 — molecular biology — Posted on 2023-10-16
2453 Comprehensive analysis of cellular specializations that initiate parallel auditory processing pathways in mice
Jing, J.; Hu, M.; Ngodup, T.; Ma, Q.; Lau, S. N. N.; Ljungberg, C.; McGinley, M. J.; Trussell, L. O.; Jiang, X.
10.1101/2023.05.15.539065 — neuroscience — Posted on 2023-10-16
2456 Phospholipid isotope tracing reveals β-catenin-driven suppression of phosphatidylcholine metabolism in hepatocellular carcinoma
VanSant-Webb, C.; Low, H. K.; Kuramoto, J.; Stanley, C. E.; Qiang, H.; Su, A.; Ross, A. N.; Cooper, C. G.; Cox, J.; Summers, S.; Evason, K.; Ducker, G. S.
10.1101/2023.10.12.562134 — cancer biology — Posted on 2023-10-16
2457 Small molecule STAT3/5 inhibitors exhibit therapeutic potential in acute myeloid leukemia and extra-nodal natural killer/T cell lymphoma
Pölöske, D.; Sorger, H.; Schönbichler, A.; de Araujo, E. D.; Neubauer, H. A.; Orlova, A.; Timonen, S. H.; Abdallah, D. I.; Ianevski, A.; Kuusanmäki, H.; Surbek, M.; Wagner, C.; Suske, T.; Metzelder, M. L.; Bergmann, M.; Dahlhoff, M.; Grebien, F.; Fleck, R.; Pirker, C.; Berger, W.; Hadzijusufovic, E.; Sperr, W. R.; Kenner, L.; Valent, P.; Aittokallio, T.; Herling, M.; Mustjoki, S.; Gunning, P.; Moriggl, R.
10.1101/2023.10.12.561697 — cancer biology — Posted on 2023-10-16
2458 Plakins are involved in the maintenance of epithelial polarity
Geay, J.; Margaron, Y.; Gentien, D.; Reyal, F.; Puisieux, A.; Guyon, L.; Thery, M.
10.1101/2023.10.16.562500 — cell biology — Posted on 2023-10-16
2459 Analysis of NIH K99/R00 Awards and the Career Progression of Awardees
Woitowich, N. C.; Hengel, S. R.; Solis, C.; Vilgalys, T. P.; Babdor, J.; Tyrrell, D. J.
10.1101/2023.01.26.525751 — scientific communication and education — Posted on 2023-10-16
2460 Revealing Molecular Mechanisms of Early-Onset Tongue Cancer by Spatial Transcriptomics
Patysheva, M.; Kolegova, E.; Khozyainova, A.; Prostakishina, E.; Menyailo, M.; Larionova, I.; Kovalev, O.; Zavyalova, M.; Fedorova, I.; Kulbakin, D.; Polyakov, A.; Yakovleva, L.; Kropotov, M.; Sukortseva, N.; Arora, R.; Choinzonov, E.; Bose, P.; Denisov, E.
10.1101/2023.10.12.562054 — cancer biology — Posted on 2023-10-16
2461 Increased deformations of aging bone marrow during mechanical loading is dispensable for cell mechanoresponse in bone analogs
Regner, A. M.; DeLeon, M.; Gibbons, K. D.; Howard, S.; Nesbitt, D. Q.; Lujan, T. J.; Fitzpatrick, C. K.; Farach-Carson, M. C.; Wu, D.; Uzer, G.
10.1101/2023.09.24.559187 — bioengineering — Posted on 2023-10-16
2462 Copy number variation and population-specific immune genes in the model vertebrate zebrafish
Schäfer, Y.; Palitzsch, K.; Leptin, M.; Whiteley, A. R.; Wiehe, T.; Suurväli, J.
10.1101/2023.08.23.554498 — genetics — Posted on 2023-10-16
2463 Polymorphic short tandem repeats make widespread contributions to blood and serum traits
Margoliash, J.; Fuchs, S.; Li, Y.; Zhang, X.; Massarat, A.; Goren, A.; Gymrek, M.
10.1101/2022.08.01.502370 — genetics — Posted on 2023-10-16
2464 Towards quantitative DNA Metabarcoding: A method to overcome PCR amplification bias
Moinard, S.; Piau, D.; Laporte, F.; Rioux, D.; Taberlet, P.; Gonindard-Melodelima, C.; Coissac, E.
10.1101/2023.10.03.560640 — ecology — Posted on 2023-10-16
2465 Mechanical activation of TWIK-related potassium channel by nanoscopic movement and rapid second messenger signaling.
Petersen, E. N.; Pavel, M. A.; Hansen, S. S.; Gudheti, M.; Wang, H.; Yuan, Z.; Murphy, K. R.; Ja, W. W.; Ferris, H. A.; Jorgensen, E. M.; Hansen, S. B.
10.1101/758896 — neuroscience — Posted on 2023-10-16
2466 Rho GTPase signaling and mDia facilitate endocytosis via presynaptic actin
Oevel, K.; Hohensee, S.; Kumar, A.; Rosas-Brugada, I.; Bartolini, F.; Soykan, T.; Haucke, V.
10.1101/2023.10.12.561997 — neuroscience — Posted on 2023-10-16
2468 Macro-scale patterns in functional connectivity associated with ongoing thought patterns and dispositional traits
Hardikar, S.; Mckeown, B.; Schaare, H. L.; Xu, T.; Lauckner, M.; Valk, S.; Margulies, D.; Turnbull, A.; Bernhardt, B.; Vos de Wael, R.; Villringer, A.; smallwood, j.
10.1101/2022.10.11.511591 — neuroscience — Posted on 2023-10-16
2470 The landscape of biomedical research
Gonzalez-Marquez, R.; Schmidt, L.; Schmidt, B. M.; Berens, P.; Kobak, D.
10.1101/2023.04.10.536208 — scientific communication and education — Posted on 2023-10-16
2472 Effect of gedunin on glioblastoma proliferation and invasiveness: in vitro and in vivo approaches
Costa, T. E. M. M.; Padua, T. A.; Pereira, J. X.; Rodrigues, V. G.; Seito, L. N.; Cunha, E. M.; Filgueiras, C. C.; Abreu-Villaca, Y.; Manhaes, A. C.; Maya-Monteiro, C. M.; Henriques, M. d. G.; Krahe, T. E.; Penido, C.
10.1101/2023.06.02.543101 — pharmacology and toxicology — Posted on 2023-10-16
2473 The DeMixSC deconvolution framework uses single-cell sequencing plus a small benchmark dataset for improved analysis of cell-type ratios in complex tissue samples
Guo, S.; Liu, X.; Cheng, X.; Jiang, Y.; Ji, S.; Liang, Q.; Koval, A.; Li, Y.; Owen, L. A.; Kim, I. K.; Aparicio, A.; Shen, J. P.; Kopetz, S.; Weinstein, J. N.; DeAngelis, M. M.; Chen, R.; Wang, W.
10.1101/2023.10.10.561733 — bioinformatics — Posted on 2023-10-16
2474 Global impact of aberrant splicing on human gene expression levels
Fair, B. J.; Abad Najar, C. B.; Zhao, J.; Lozano, S.; Reilly, A. K.; Mossian, G.; Staley, J. P.; Wang, J.; Li, Y. I.
10.1101/2023.09.13.557588 — genomics — Posted on 2023-10-16
2476 The evolution of whole-brain turbulent dynamics during recovery from traumatic brain injury
Martinez-Molina, N.; Escrichs, A.; Sanz Perl, Y.; Sarkamo, T.; Sihvonen, A. J.; Kringelbach, M. L.; Deco, G.
10.1101/2022.11.30.518501 — neuroscience — Posted on 2023-10-16
2482 Blocking Formation of Neurotoxic Reactive Astrocytes is Beneficial Following Stroke
Prescott, K.; Munch, A. E.; Brahms, E.; Weigel, M. M.; Inoue, K.; Buckwalter, M. S.; Liddelow, S.; Peterson, T.
10.1101/2023.10.11.561918 — neuroscience — Posted on 2023-10-16
2484 Susceptibility to multitasking in chronic stroke is associated to damage of the multiple demand system and leads to lateralized visuospatial deficits
Blini, E.; D'Imperio, D.; Romeo, Z.; De Filippo De Grazia, M.; Passarini, L.; Pilosio, C.; Meneghello, F.; Bonato, M.; Zorzi, M.
10.1101/2023.10.11.561866 — neuroscience — Posted on 2023-10-16
2490 Reassessing the role of foot power in human gait
Yetman, Q.; Welte, L.; Shimizu, A.; Rainbow, M. J.
10.1101/2023.10.11.561917 — physiology — Posted on 2023-10-16
2491 Septin 7 Interacts With Numb To Preserve Sarcomere Structural Organization And Muscle Contractile Function.
De Gasperi, R.; Csernoch, L.; Dienes, B.; Gonczi, M.; Chakrabarty, J. K.; Goeta, S.; Aslan, A.; Toro, C. A.; Karasik, D.; Brown, L. M.; Brotto, M.; Cardozo, C. P.
10.1101/2023.05.11.540467 — physiology — Posted on 2023-10-16
2492 Tumor-Associated Macrophages Expand Chemoresistant, Ovarian Cancer Stem-Like Cells
Sharrow, A. C.; Ho, M.; Dua, A.; Buj, R.; Blenman, K. R. M.; Orsulic, S.; Buckanovich, R.; Aird, K. M.; Wu, L.
10.1101/2023.07.17.549067 — cancer biology — Posted on 2023-10-16
2494 Regulatory Landscape Enrichment Analysis (RLEA) using gaiaAssociation
Sosa, E. A.; Rosean, S.; O'Shea, D.; Raj, S. M.; Seoighe, C.; Greally, J. M.
10.1101/2023.10.11.561933 — bioinformatics — Posted on 2023-10-16
2497 Designing efficient randstrobes for sequence similarity analyses
Karami, M.; Mohammadi, A. S.; Martin, M.; Ekim, B.; Shen, W.; Guo, L.; Xu, M.; Pibiri, G. E.; Patro, R.; Sahlin, K.
10.1101/2023.10.11.561924 — bioinformatics — Posted on 2023-10-16
2499 Development of an MR-guided focused ultrasound (MRgFUS) lesioning approach for small and deep structures in the rat brain
Cornelssen, C.; Payne, A.; Parker, D.; Alexander, M.; Merrill, R.; Senthilkumar, S.; Christensen, J.; Wilcox, K. S.; Odeen, H.; Rolston, J. D.
10.1101/2023.10.11.561930 — bioengineering — Posted on 2023-10-16
2500 Inflammatory stress-mediated chromatin changes underlie dysfunction in endothelial cells.
Liu, H.; Caliz, A. D.; Learnard, H.; Koupenova, M.; Keaney, J. F.; Kant, S.; Zhu, L. J.; Vertii, A.
10.1101/2023.10.11.561959 — genomics — Posted on 2023-10-16
2501 Tropical high-altitude insects show limited capacity to handle high temperatures
Mayekar, H. V.; Solanki, P. S.; Arya, H.; Aradhya, R.; Suravajhala, P.; Loeschcke, V.; Rajpurohit, S.
10.1101/2022.09.10.507406 — evolutionary biology — Posted on 2023-10-16
2502 Kinetochore and ionomic adaptation to whole genome duplication
Bray, S. M.; Hamala, T.; Zhou, M.; Busoms, S.; Fischer, S.; Desjardins, S. D.; Mandakova, T.; Moore, C.; Mathers, T. C.; Cowan, L.; Monnahan, P.; Koch, J.; Wolf, E. M.; Lysak, M. A.; Kolar, F.; Higgins, J. D.; Koch, M. A.; Yant, L.
10.1101/2023.09.27.559727 — evolutionary biology — Posted on 2023-10-16
2505 Phosphorylation bar-coding of Free Fatty Acid receptor 2 is generated in a tissue-specific manner
Barki, N.; Jenkins, L.; Marsango, S.; Dedeo, D.; Bolognini, D.; Dwomoh, L.; Abdelmalik, A. M.; Nilsen, M.; Stoffels, M.; Schulz, S.; Nagel, F.; Tobin, A. B.; Milligan, G.
10.1101/2023.09.01.555873 — cell biology — Posted on 2023-10-16
2506 Endocannabinoids and their receptors modulate endometriosis pathogenesis and immune response
Lingegowda, H.; Zutautas, K. B.; Wei, Y.; Yolmo, P.; Sisnett, D. J.; McCallion, A.; Koti, M.; Tayade, C.
10.1101/2023.10.11.561929 — immunology — Posted on 2023-10-16
2507 Divergent changes in PBN excitability in a mouse model of neuropathic pain
Torruella-Suarez, M. L.; Neugebauer, B.; Flores-Felix, K.; Keller, A.; Carrasquillo, Y.; Cramer, N.
10.1101/2023.10.11.561891 — neuroscience — Posted on 2023-10-16
2508 Genetic ablation of neuronal mitochondrial calcium uptake halts Alzheimer's disease progression
Jadiya, P.; Kolmetzky, D. W.; Tomar, D.; Thomas, M.; Cohen, H. M.; Khaledi, S.; Garbincius, J. F.; Hildebrand, A. N.; Elrod, J. W.
10.1101/2023.10.11.561889 — neuroscience — Posted on 2023-10-16
2510 Peripherally derived LGI1-reactive monoclonal antibodies cause epileptic seizures in vivo
Upadhya, M.; Kirmann, T.; Wilson, M.; Simon, C. M.; Dhangar, D.; Geis, C.; Williams, R.; Woodhall, G.; Hallermann, S.; Irani, S.; Wright, S.
10.1101/2023.10.11.561725 — neuroscience — Posted on 2023-10-16
2511 Engineering Material Properties of Transcription Factor Condensates to Control Gene Expression in Mammalian Cells and Mice
Fischer, A. A. M.; Kong, D.; Grimm, M. M.; Grether, J.; Groth, J.; Fliegauf, M.; Grimbacher, B.; Ye, H.; Weber, W.
10.1101/2023.10.16.562453 — synthetic biology — Posted on 2023-10-16
2519 High quality genome of the brown hare (Lepus europaeus) with chromosome-level scaffolding
Michell, C.; Collins, J.; Laine, P. K.; Fekete, Z.; Tapanainen, R.; Wood, J. M. D.; Goffart, S.; Pohjoismaki, J. L. O.
10.1101/2023.08.29.555262 — genomics — Posted on 2023-10-16
2520 Early Neolithic forest farming at Seven Springs, Martlesham, Suffolk from sedaDNA and pollen
Hudson, S. M.; Allen, S. J.; Alsos, I. G.; Curl, J.; Heintzman, P. D.; Hughes, P.; Gardiner, L.; Lloyd-Smith, L.; Pears, B. R.; Scaife, R.; Stoof-Leichsenring, K. R.; Brown, A.
10.1101/2023.10.11.561859 — ecology — Posted on 2023-10-16
2522 Tracking neurons across days with high-density probes
van Beest, E. H.; Bimbard, C.; Fabre, J. M. J.; Takacs, F.; Coen, P. H.; Lebedeva, A.; Harris, K. D.; Carandini, M.
10.1101/2023.10.12.562040 — neuroscience — Posted on 2023-10-16
2525 HERC3 E3 ligase provides an ERAD branch eliminating select membrane proteins
Kamada, Y.; Ohnishi, Y.; Nakashima, C.; Fujii, A.; Terakawa, M.; Hamano, I.; Nakayamada, U.; Katoh, S.; Hirata, A.; Tateishi, H.; Fukuda, R.; Takahashi, H.; Lukacs, G. L.; Okiyoneda, T.
10.1101/2023.10.16.562477 — cell biology — Posted on 2023-10-16
2527 Fitness landscape of substrate-adaptive mutations in evolved APC transporters
Karapanagioti, F.; Atlason, U. A.; Slotboom, D. J.; Poolman, B.; Obermaier, S.
10.1101/2023.10.12.562049 — biochemistry — Posted on 2023-10-16
2530 Non-responsive Celiac disease symptoms associated with microbiome network structure and function
Marcos-Zambrano, L. J.; Lacruz-Pleguezuelos, B.; Aguilar-Aguilar, E.; Loria-Kohen, V.; Valdes, A.; Cifuentes, A.; Ramirez de Molina, A.; Carrillo de Santa Pau, E.
10.1101/2023.10.14.562350 — microbiology — Posted on 2023-10-16
2535 Cortical and behavioural tracking of rhythm in music: Effects of pitch predictability, enjoyment, and expertise
Keitel, A.; Pelofi, C.; Guan, X.; Watson, E.; Wight, L.; Allen, S.; Mencke, I.; Keitel, C.; Rimmele, J. M.
10.1101/2023.10.15.562351 — neuroscience — Posted on 2023-10-16
2540 Growth retardation in a mouse model of Kabuki syndrome 2 bears mechanistic similarities to Kabuki syndrome 1
Gao, C. W.; Lin, W.-Y.; Riddle, R. C.; Chopra, S.; Boukas, L.; Hansen, K. D.; Bjornsson, H. T.; Fahrner, J. A.
10.1101/2023.10.15.562327 — genetics — Posted on 2023-10-16
2541 Lupus IgA1 autoantibodies synergize with IgG to enhance plasmacytoid dendritic cell responses to RNA-containing immune complexes
Waterman, H. R.; Dufort, M. J.; Posso, S. E.; Ni, M.; Li, L. Z.; Zhu, C.; Raj, P.; Smith, K. D.; Buckner, J. H.; Hamerman, J. A.
10.1101/2023.09.07.556743 — immunology — Posted on 2023-10-15
2545 Hepatic lipid-associated macrophages mediate the beneficial effects of bariatric surgery against MASH
Fredrickson, G.; Florczak, K.; Barrow, F.; Dietsche, K.; Wang, H.; Parthiban, P.; Almutlaq, R.; Adeyi, O.; Herman, A.; Bartolomucci, A.; Staley, C.; Jahansouz, C.; Williams, J. W.; Mashek, D.; Ikramuddin, S.; Revelo, X.
10.1101/2023.06.11.544503 — physiology — Posted on 2023-10-15
2546 ATOMDANCE: kernel-based denoising and allosteric resonance analysis for functional and evolutionary comparisons of protein dynamics
Babbitt, G. A.; Rajendran, M.; Lynch, M. L.; Asare-Bediako, R.; Mouli, L. T.; Ryan, C. J.; Srivastava, H.; Rynkiewicz, P.; Phadke, K.; Reed, M. L.; Moore, N.; Ferran, M. C.; Fokoue, E. P.
10.1101/2023.04.20.537698 — biophysics — Posted on 2023-10-15
2547 Genomic language model predicts protein co-regulation and function
Hwang, Y.; Cornman, A. L.; Kellogg, E.; Ovchinnikov, S.; Girguis, P.
10.1101/2023.04.07.536042 — bioinformatics — Posted on 2023-10-15
2548 Dividing out quantification uncertainty allows efficient assessment of differential transcript expression with edgeR
Baldoni, P. L.; Chen, Y.; Hediyeh-zadeh, S.; Liao, Y.; Dong, X.; Ritchie, M. E.; Shi, W.; Smyth, G. K.
10.1101/2023.04.02.535231 — bioinformatics — Posted on 2023-10-15
2552 Adolescent chronic sleep restriction promotes alcohol drinking in adulthood: evidence from epidemiological and preclinical data.
Faniyan, O. O.; Marcotulli, D.; Simayi, R.; Del Gallo, F.; De Carlo, S.; Ficiara, E.; Caramaschi, D.; Richmond, R.; Franchini, D.; Bellesi, M.; Ciccocioppo, R.; de Vivo, L.
10.1101/2023.10.11.561858 — neuroscience — Posted on 2023-10-15
2555 Dissociation of reliability, heritability, and predictivity in coarse- and fine-scale functional connectomes during development
Busch, E. L.; Rapuano, K. M.; Anderson, K. M.; Rosenberg, M. D.; Watts, R.; Casey, B.; Haxby, J. V.; Feilong, M.
10.1101/2022.05.24.493295 — neuroscience — Posted on 2023-10-15
2556 Experimentally induced active and quiet sleep engage non-overlapping transcriptional programs in Drosophila
Anthoney, N.; Tainton-Heap, L.; Luong, H.; Notaras, E.; Kewin, A. B.; Zhao, Q.; Perry, T.; Batterham, P.; Shaw, P.; van Swinderen, B.
10.1101/2023.04.03.535331 — neuroscience — Posted on 2023-10-15
2559 HyperPRI: A Dataset of Hyperspectral Images for Underground Plant Root Study
Chang, S. J.; Chowdhry, R.; Song, Y.; Mejia, T.; Hampton, A.; Kucharski, S.; Sazzad, T.; Zhang, Y.; Koppal, S. J.; Wilson, C. H.; Gerber, S.; Tillman, B.; Resende, M. F.; Hammond, W. M.; Zare, A.
10.1101/2023.09.29.559614 — plant biology — Posted on 2023-10-15
2560 Physiological Profiles of Male and Female CrossFit Athletes
Hodzic, D.; D'Hulst, G.; Leuenberger, R.; Arnet, J.; Westerhuis, E.; Roth, R.; Schmidt-Trucksass, A.; Knaier, R.; Wagner, J.
10.1101/2023.10.11.561828 — physiology — Posted on 2023-10-15
2561 Quantification of membrane fluidity in bacteria using TIR-FCS
Barbotin, A.; Billaudeau, C.; Sezgin, E.; CARBALLIDO LOPEZ, R.
10.1101/2023.10.13.562271 — biophysics — Posted on 2023-10-15
2564 Long-term dynamics of the 'Serratia marcescens complex' in the hospital-built environment
Aracil-Gisbert, S.; Fernandez-de-Bobadilla, M. D.; Guerra-Pinto, N.; Serrano-Calleja, S.; Perez-Cobas, A. E.; Soriano, C.; De Pablo, R.; Lanza, V. F.; Perez-Viso, B.; Reuter, S.; Hasman, H.; Canton, R.; Baquero, F.; Coque, T. M.
10.1101/2023.10.15.562376 — microbiology — Posted on 2023-10-15
2565 The RNA binding protein, HNRNPA2B1, regulates IFNG signaling in macrophages
Mohammed Salih, M.; Weindel, C. G.; Malekos, E.; Sudek, L.; Katzman, S.; Mabry, C. J.; Coleman, A.; Azam, S.; Watson, R. O.; Patrick, K. L.; Carpenter, S.
10.1101/2023.10.12.562050 — immunology — Posted on 2023-10-15
2566 RBM39 shapes innate immunity through transcriptional and splicing control of IRF3 and other key factors
Li, T.-F.; Lang, A.; Rothhaar, P.; Gruenvogel, O.; Colasanti, O.; Olivera Ugarte, S. M.; Traut, J.; Piras, A.; Acosta-Rivero, N.; Goncalves Magalhaes, V.; Springer, E.; Betz, A.; Huang, H.-E.; Park, J.; Qiu, R.; Gnouamozi, G. E.; Mehnert, A.-K.; Dao Thi, V. L.; Urban, S.; Muckenthaler, M.; Schlesner, M.; Wohlleber, D.; Binder, M.; Bartenschlager, R.; Pichlmair, A.; Lohmann, V.
10.1101/2023.10.13.562221 — immunology — Posted on 2023-10-15
2568 New insights into iodide metabolism based on preclinical models: impact on radiotherapy efficacy and protection against radioactive iodine exposure.
Guglielmi, J.; D'Andrea, G.; Graslin, F.; Chatti, K.; Schiazza, A.; Lindenthal, S.; Darcourt, J.; Cambien, B.; Pourcher, T.
10.1101/2023.10.11.561684 — physiology — Posted on 2023-10-15
2575 IRF8-mutant B cell lymphoma evades immunity through a CD74-dependent deregulation of antigen processing and presentation in MHC CII complexes
Qiu, Z.; Khalife, J.; Lin, A.-P.; Ethiraj, P.; Jaafar, C.; Chiou, L.; Huelgas-Morales, G.; Aslam, S.; Arya, S.; Gupta, Y.; Dahia, P.; Aguiar, R.
10.1101/2023.10.14.560755 — cancer biology — Posted on 2023-10-15
2578 Actin-based deformations of the nucleus control multiciliated ependymal cell differentiation.
Mahuzier, A.; Basso, M.; Lennon-Dumenil, A.-M.; Faucourt, M.; Meunier, A.; Spassky, N.; Delgehyr, N.
10.1101/2023.10.13.562225 — developmental biology — Posted on 2023-10-15
2579 Repression of mRNA translation initiation by GIGYF1 via blocking the eIF3-eIF4G1 interaction
Choi, J.-H.; Luo, J.; Hesketh, G. G.; Guo, S.; Pistofidis, A.; Ladak, R. J.; An, Y.; Alain, T.; Schmeing, M.; Gingras, A.-C.; Duchaine, T.; Zhang, X.; Sonenberg, N.; Jafarnejad, S. M.
10.1101/2023.10.14.562322 — cell biology — Posted on 2023-10-15
2580 STING induces LUBAC-mediated synthesis of linear ubiquitin chains to stimulate innate immune signaling
Fischer, T. D.; Bunker, E. N.; Zhu, P.-P.; Le Guerroue, F.; Dominguez-Martin, E.; Scavone, F.; Cohen, R. E.; Yao, T.; Wang, Y.; Werner, A.; Youle, R. J.
10.1101/2023.10.14.562349 — cell biology — Posted on 2023-10-15
2584 Rtf1-dependent transcriptional pausing regulates cardiogenesis
Langenbacher, A. D.; Lu, F.; Tsang, L.; Huang, Z. Y. S.; Keer, B.; Tian, Z.; Eide, A.; Pellegrini, M.; Nakano, H.; Nakano, A.; Chen, J.-N.
10.1101/2023.10.13.562296 — developmental biology — Posted on 2023-10-15
2586 PCSK9 inhibition protects mice from food allergy
Lorant, V.; Klein, M.; Garcon, D.; Sotin, T.; Frey, S.; Cheminant, M.-A.; Ayer, A.; Croyal, M.; Flet, L.; Colas, L.; Cariou, B.; Bouchaud, G.; Le May, C.
10.1101/2023.10.10.561796 — physiology — Posted on 2023-10-15
2587 DNA Methylation Signatures in Breast Cancer: A Systematic Review and Meta-Analysis
Trasierras-Fresco, A. M.; Gomez-Martinez, H.; Andreu, Z.; Hidalgo, M. R.; Gomez-Cabanes, B.; Poley Gil, M.; Malmierca-Merlo, P.; Romera-Giner, S.; Crespo, D.; Serna-Blasco, R.; Romero, A.; Lopez-Guerrero, J. A.; de la Iglesia Vaya, M.; Garcia-Garcia, F.
10.1101/2022.10.15.512358 — cancer biology — Posted on 2023-10-15
2589 Belt and braces: two escape ways to maintain the cassette reservoir of large chromosomal integrons
Richard, E.; Darracq, B.; Littner, E.; Millot, G.; Conte, V.; Cokelaer, T.; Engelstaedter, J.; Rocha, E. P.; Mazel, D.; Loot, C.
10.1101/2023.08.31.555669 — genetics — Posted on 2023-10-15
2590 Phospholipid Scramblase-1 is required for efficient neurotransmission and synaptic vesicle retrieval at cerebellar synapses
Caputo, M.; Ivanova, D.; Chasserot Golaz, S.; Doussau, F.; Anne Marie, H.; Ozkan, S.; Ecard, J.; Bader, M. F.; Vitale, N.; Cousin, M. A.; Toth, P.; Gasman, S.; Ory, S.
10.1101/2023.10.14.562324 — cell biology — Posted on 2023-10-15
2591 Resolving the pharmacological redox-sensitivity of SARS-CoV-2 PLpro in drug repurposing screening enabled identification of the competitive GRL-0617 binding site inhibitor CPI-169
Kuzikov, M.; Morasso, S.; Reinshagen, J.; Wolf, M.; Monaco, V.; Cozzolino, F.; Grdadolnik, S. G.; Sket, P.; Plavec, J.; Iaconis, D.; Summa, V.; Esposito, F.; Tramontano, E.; Monti, M.; Beccari, A. R.; Windshugel, B.; Gribbon, P.; Storici, P.; Zaliani, A.
10.1101/2023.10.11.561987 — molecular biology — Posted on 2023-10-15
2592 Secretory Leukocyte Protease Inhibitor Protects Against Severe Urinary Tract Infection in Mice
Rosen, A.; Lint, M.; Voelker, D.; Gilbert, N.; Tomera, C.; Santiago Borges, J.; Wallace, M. A.; Hannan, T.; Burnham, C.-A. D.; Hultgren, S.; Kau, A.
10.1101/2023.10.10.561753 — immunology — Posted on 2023-10-15
2596 Cholinergic modulation of exploration in rats performing a spatial memory task
Cassity, S. T.; Choi, I. J.; Igbasanmi, A. M.; Bickford, S. C.; Moore, K. T.; Seraiah, A. E.; O'Shea, L.; Layfield, D.; Newman, E. L.
10.1101/2023.10.14.559618 — neuroscience — Posted on 2023-10-14
2597 Identification Of Candidate Genes And Pathways Linked To The Temperament Trait In Sheep
Romaniuk, E.; Vera, B.; Peraza, P.; Ciappesoni, G.; Damian, J. P.; van Lier, E.
10.1101/2023.10.12.562033 — genomics — Posted on 2023-10-14
2598 The genetic basis of novel trait gain in walking fish
Herbert, A. L.; Allard, C. A.; McCoy, M. J.; Wucherpfennig, J. I.; Krueger, S. P.; Chen, H. I.; Gourlay, A. N.; Jackson, K. D.; Abbo, L. A.; Bennett, S. H.; Sears, J. D.; Rhyne, A. L.; Bellono, N. W.; Kingsley, D. M.
10.1101/2023.10.14.562356 — evolutionary biology — Posted on 2023-10-14
2599 Adaptive genomic variation is linked to a climatic gradient in a social wasp
Cook, H. L.; Miller, S. E.; Giri, G.; Loope, K. J.; Sheehan, M. J.; Uy, F. M. K.
10.1101/2023.10.12.561994 — evolutionary biology — Posted on 2023-10-14
2603 Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege
Strobl, K.; Klufa, J.; Jin, R.; Artner-Gent, L.; Krauss, D.; Novoszel, P.; Strobl, J.; Stary, G.; Vujic, I.; Griss, J.; Holcmann, M.; Farlik, M.; Homey, B.; Sibilia, M.; Bauer, T.
10.1101/2023.10.11.561653 — immunology — Posted on 2023-10-14
2604 Disruption of myelin structure and oligodendrocyte maturation in a pigtail macaque model of congenital Zika infection
Tisoncik-Go, J.; Stokes, C.; Whitmore, L.; Newhouse, D. J.; Voss, K.; Gustin, A.; Song, C.-J.; Smith, E.; Stencel-Baerenwald, J.; Parker, E. D.; Snyder, J. M.; Shaw, D.; Rajagopal, L.; Kapur, R. P.; Waldorf, K. A.; Gale, M.
10.1101/2023.10.11.561759 — immunology — Posted on 2023-10-14
2606 Alasemenia, the earliest ovule with three wings and without cupule
Wang, D.; Yang, J.; Liu, L.; Zhou, Y.; Xu, P.; Qin, M.; Huang, P.
10.1101/2023.10.11.561822 — paleontology — Posted on 2023-10-14
2610 Assembly and annotation of two high-quality columbid reference genomes from sequencing of a Columba livia x Columba guinea F1 hybrid
Maclary, E. T.; Holt, C.; Concepcion, G. T.; Sovic, I.; Vickrey, A. I.; Yandell, M.; Kronenberg, Z.; Shapiro, M. D.
10.1101/2023.10.11.561892 — genomics — Posted on 2023-10-14
2611 Extraordinary levels of per- and polyfluoroalkyl substances (PFAS) in vertebrate animals at a New Mexico desert oasis: multiple pathways for wildlife and human exposure
Witt, C. C.; Gadek, C. R.; Cartron, J.-L. E.; Andersen, M. J.; Campbell, M. L.; Castro-Farias, M.; Gyllenhaal, E. F.; Johnson, A. B.; Malaney, J. L.; Montoya, K. N.; Patterson, A.; Vinciguerra, N. T.; Williamson, J. L.; Cook, J. A.; Dunnum, J. L.
10.1101/2023.10.11.561778 — ecology — Posted on 2023-10-14
2616 Non-responsive Celiac disease symptoms associated with microbiome network structure and function
Marcos-Zambrano, L. J.; Lacruz-Pleguezuelos, B.; Aguilar-Aguilar, E.; Loria-Kohen, V.; Valdes, A.; Cifuentes, A.; Ramirez de Molina, A.; Castillo de Santa Pau, E.
10.1101/2023.10.14.562350 — microbiology — Posted on 2023-10-14
2619 A role for retro-splenial cortex in the task-related P3 network
Das, D.; Shaw, M. E.; Hamalainen, M. S.; Dykstra, A. R.; Doll, L.; Gutschalk, A.
10.1101/2023.03.03.530970 — neuroscience — Posted on 2023-10-14
2620 Regulatory T cells limit age-associated retinal inflammation and neurodegeneration
Llorian-Salvador, M.; Guzman de la Fuente, A.; McMurran, C. E.; Penalva, R.; Dombrowski, Y.; Stitt, A.; Fitzgerald, D. C.
10.1101/2023.10.11.561874 — neuroscience — Posted on 2023-10-14
2623 VEGF-C expression in TAMs rewires the metastaticfate of breast cancer cells
Banjerjee, K. S.; Bekkhus, T.; Kerzel, T.; Ferreira, S. d. S.; Wallmann, T.; Wallerius, M.; Landwehr, L. S.; Agardy, D. A.; Bergh, J.; Bartish, M.; Hartman, J.; Ostman, A.; Squadrito, M. L.; Rolny, C.
10.1101/2022.01.26.468593 — cancer biology — Posted on 2023-10-14
2624 Tubule jamming in the developing mouse kidney creates cyclical mechanical stresses in nephron-forming niches
Viola, J. M.; Liu, J.; Prahl, L. S.; Huang, A.; Chan, T. J.; Hayward-Lara, G.; Porter, C. M.; Shi, C.; Zhang, J.; Hughes, A. J.
10.1101/2022.06.03.494718 — bioengineering — Posted on 2023-10-14
2627 Antiviral capacity of the early CD8 T-cell response is predictive of natural control of SIV infection
Vemparala, B.; Madelain, V.; Passaes, C.; Millet, A.; Avettand-Fenoel, V.; Djidjou-Demasse, R.; Dereuddre-Bosquet, N.; Le Grand, R.; Rouzioux, C.; Vaslin, B.; Saez-Cirion, A.; Guedj, J.; Dixit, N. M.
10.1101/2023.10.13.562306 — microbiology — Posted on 2023-10-14
2628 Ex vivo structures from spinach leaves
Wang, J.; Johansen, N. T.; Gamon, L. F.; Zhao, Z.; Guo, Z.; Wang, Y.; Fuglsang, A. T.; Gourdon, P.; Wang, K.
10.1101/2023.10.13.562012 — biochemistry — Posted on 2023-10-14
2629 Effects of isochoric freezing on quality characteristics of raw bovine milk
Maida, A.; Bilbao-Sainz, C.; Karman, A.; Takeoka, G.; Powell-Palm, M. J.; Rubinsky, B.
10.1101/2023.10.12.562068 — biochemistry — Posted on 2023-10-14
2630 Synaptic Activity Causes Minute-scale Changes in BAF Complex Composition and Function
Gourisankar, S.; Wenderski, W.; Paulo, J. A.; Kim, S. H.; Roepke, K.; Ellis, C.; Gygi, S. P.; Crabtree, G.
10.1101/2023.10.13.562244 — molecular biology — Posted on 2023-10-14
2632 Escherichia coli plasmidome maps the game of clones
Arredondo-Alonso, S.; Pontinen, A. K.; Gama, J.; Gladstone, R. A.; Harms, K.; Tonkin-Hill, G.; Thorpe, H. A.; Simonsen, G. S.; Samuelsen, O.; Johnsen, P. J.; Corander, J.
10.1101/2023.10.14.562336 — microbiology — Posted on 2023-10-14
2633 Deletion of SMC renders FtsK essential in Corynebacterium glutamicum
Peng, F.; Giacomelli, G.; Meyer, F. M.; Linder, M.; Haak, M.; Rueckert-Reed, C.; Weiss, M.; Kalinowski, J.; Bramkamp, M.
10.1101/2023.10.14.562338 — microbiology — Posted on 2023-10-14
2637 Hidden evolutionary constraints dictate the retention of coronavirus accessory genes
Goldstein, S. A.; Feeley, T. M.; Babler, K. M.; Hilbert, Z. A.; Downhour, D. M.; Moshiri, N.; Elde, N. C.
10.1101/2023.10.12.561935 — evolutionary biology — Posted on 2023-10-14
2638 Antibodies utilizing VL6-57 light chains target a convergent cryptic epitope on SARS-CoV-2 spike protein driving the genesis of Omicron variants
Yan, Q.; Gao, X.; Liu, B.; Hou, R.; He, P.; Ma, Y.; Zhang, Y.; Zhang, Y.; Li, Z.; Chen, Q.; Wang, J.; Huang, X.; Liang, H.; Chen, X.; Niu, X.; He, J.; Chen, L.; Zhao, J.; Xiong, X.
10.1101/2023.10.12.561995 — biochemistry — Posted on 2023-10-14
2639 FluxNorm: Toolbox for metabolic flux assay normalization by in situ cell counting
Djaja, N. A.; Bracha, T.; Yu, S. B.; Wang, H.; Carlson, N. M.; Pekkurnaz, G.
10.1101/2023.10.13.562314 — cell biology — Posted on 2023-10-14
2640 A PARP14/TARG1-Regulated RACK1 MARylation Cycle Drives Stress Granule Dynamics in Ovarian Cancer Cells
Challa, S.; Nandu, T.; Kim, H. B.; Gong, A.; Renshaw, C. W.; Li, W.-C.; Tan, X.; Camacho, C. V.; Chen, J.; Kraus, W. L.
10.1101/2023.10.13.562273 — cell biology — Posted on 2023-10-14
2641 High confidence glycosomal membrane protein inventory unveils trypanosomal Peroxin PEX15
Krishna, C. K.; Das, H.; Hohnen, L.; Schliebs, W.; Oeljeklaus, S.; Warscheid, B.; Kalel, V. C.; Erdmann, R.
10.1101/2023.10.13.562043 — cell biology — Posted on 2023-10-14
2642 The H3.3 K36M oncohistone disrupts the establishment of epigenetic memory through loss of DNA methylation
Sinha, J.; Nickels, J. F.; Thurm, A. R.; Ludwig, C. H.; Archibald, B. N.; Hinks, M. M.; Wan, J.; Fang, D.; Bintu, L.
10.1101/2023.10.13.562147 — cell biology — Posted on 2023-10-14
2643 The fatty liver disease-causing protein PNPLA3-I148M alters lipid droplet-Golgi dynamics
Sherman, D. J.; Liu, L.; Mamrosh, J. L.; Xie, J.; Ferbas, J.; Lomenick, B.; Ladinsky, M. S.; Verma, R.; Rulifson, I. C.; Deshaies, R. J.
10.1101/2023.10.13.562302 — cell biology — Posted on 2023-10-14
2646 Diversity of visual inputs to Kenyon cells of the Drosophila mushroom body
Ganguly, I.; Heckman, E. L.; Litwin-Kumar, A.; Clowney, E. J.; Behnia, R.
10.1101/2023.10.12.561793 — neuroscience — Posted on 2023-10-14
2648 Cnot3 is required for male germ cell development and spermatogonial stem cell maintenance
Chen, Q.; Malki, S.; Xu, X.; Bennett, B.; Lackford, B. L.; Kirsanov, O.; Geyer, C. B.; Hu, G.
10.1101/2023.10.13.562256 — developmental biology — Posted on 2023-10-14
2649 Liver size is predetermined in the neonate by adding lobules at the periphery
Azizoglu, D. B.; Perez, K.; Zheng, S. L.; Rahman, S.; Rim, E. Y.; Anbarchian, T.; Fish, M.; Loh, K. M.; Red-Horse, K.; Nusse, R.
10.1101/2023.10.12.562109 — developmental biology — Posted on 2023-10-14
2650 IL-1β inhibition partially negates the beneficial effects of diet-induced lipid lowering
Karnewar, S.; KARNEWAR, V.; Deaton, R. A.; Shankman, L. S.; Benavente, E.; Williams, C.; Bradley, X.; Alencar, G. F.; Bulut, G.; Kirmani, S.; Baylis, R.; Zunder, E.; den Ruijter, H. H.; Pasterkamp, G.; Owens, G. K.
10.1101/2023.10.13.562255 — cell biology — Posted on 2023-10-14
2651 Fucose is an essential feature in cryoprotective polysaccharides
Guerreiro, B. M.; Concordio-Reis, P.; Pericao, H.; Martins, F.; Moppert, X.; Guezennec, J.; Lima, J. C.; Silva, J. C.; Freitas, F.
10.1101/2023.10.13.562212 — cell biology — Posted on 2023-10-14
2655 Structural-Functional Brain Network Coupling Predicts Human Cognitive Ability
Popp, J. L.; Thiele, J. A.; Faskowitz, J.; Seguin, C.; Sporns, O.; Hilger, K.
10.1101/2023.02.09.527639 — neuroscience — Posted on 2023-10-14
2657 Chlorophyll to Zeaxanthin Energy Transfer in Non-Photochemical Quenching: An Exciton Annihilation-free Transient Absorption Study
Lee, T.-Y.; Lam, L.; Patel-Tupper, D.; Roy, P. P.; Ma, S. A.; Lucas-DeMott, A.; Karavolias, N. G.; Niyogi, K. K.; Fleming, G. R.
10.1101/2023.10.11.561813 — plant biology — Posted on 2023-10-14
2659 Arabidopsis AGO1 N-terminal Poly-Q domain promotes phase separation and association with stress granules during heat stress
Blagojevic, A.; Baldrich, P.; Schiaffini, M.; Lechner, E.; Baumberger, N.; Hammann, P.; Elmayan, T.; Garcia, D.; Vaucheret, H.; Meyers, B.; Genschik, P.
10.1101/2023.10.12.562039 — plant biology — Posted on 2023-10-14
2662 The renal capsule, a vibrant and adaptive cell environment of the kidney in homeostasis and aging
Korin, B.; Avraham, S.; Moncada, R.; Ho, T.; Tleugabulova, M. C.; Menon, H.; Darmanis, S.; Liang, Y.; Modrusan, Z.; Chalouni, C.; Victoria, C.; Rangell, L.; Havnar, C.; Ewart, W.; Jones, C.; Jiang, J.; Dunlap, D.; Dohse, M.; McKay, A.; Webster, J. D.; Durinck, S.; Shaw, A. S.
10.1101/2023.05.11.540033 — immunology — Posted on 2023-10-14
2663 A Normative Framework Dissociates Need and Motivation in Hypothalamic Neurons
Kim, K. S.; Lee, Y. H.; Kim, Y.-B.; Yun, J. W.; Song, H. Y.; Park, J. S.; Jung, S.-H.; Sohn, J.-W.; Kim, K. W.; Kim, H. R.; Choi, H. J.
10.1101/2023.10.01.560411 — neuroscience — Posted on 2023-10-14
2666 The effects of genome size on cell size and the functional composition and morphology of leaves: a case study in Rhododendron (Ericaceae)
Dastpak, A.; Williams, M.; Perkins, S.; Perkins, J.; Horn, C.; Thompson, P.; Ryan, C.; Medeiros, J.; An, Y.-D.; Jiang, G.-F.; Simonin, K.; Roddy, A.
10.1101/2023.10.13.562260 — plant biology — Posted on 2023-10-14
2670 Maize (Zea mays L.) interaction with the arbuscular mycorrhizal fungus Rhizophagus irregularis allows mitigation of nitrogen deficiency stress: physiological and molecular characterization
Decouard, B.; Chowdhury, N. B.; Saou, A.; Rigault, M.; Quillere, I.; Sapir, T.; Marmagne, A.; Paysant le Roux, C.; Launay-Avon, A.; Guerard, F.; Gakiere, B.; Mauve, C.; Levy-Leduc, C.; Barbillon, P.; Saha, R.; Hirel, B.; Courty, P.-E.; Wipf, D.; DELLAGI, A.
10.1101/2023.10.13.562190 — plant biology — Posted on 2023-10-14
2671 Epigenetic differences between wild and cultivated grapevines highlight the contribution of DNA methylation during crop domestication
Rodriguez Izquierdo, A.; Carrasco, D.; Anand, L.; Magnani, R.; Catarecha, P.; Arroyo-Garcia, R.; Rodriguez Lopez, C. M.
10.1101/2023.10.12.562052 — plant biology — Posted on 2023-10-14
2672 Optoelectronic enhancement of photocurrent by cyanobacteria on sustainable AP-VPP-fabricated PEDOT electrodes
Wey, L. T.; Yewale, R.; Hautala, E.; Hannonen, J.; Katavisto, K.; Kvarnstrom, C.; Allahverdiyeva, Y.; Damlin, P.
10.1101/2023.10.11.561827 — plant biology — Posted on 2023-10-14
2674 Coherent olfactory bulb gamma oscillations arise from coupling independent columnar oscillators
Peace, S. T.; Johnson, B. C.; Werth, J. C.; Li, G.; Kaiser, M. E.; Fukunaga, I.; Schaefer, A. T.; Molnar, A. C.; Cleland, T. A.
10.1101/213827 — neuroscience — Posted on 2023-10-14
2675 A Normative Framework Dissociates Need and Motivation in Hypothalamic Neurons
Kim, K. S.; Lee, Y. H.; Kim, Y.-B.; Yun, J. W.; Song, H. Y.; Park, J. S.; Jung, S.-H.; Sohn, J.-W.; Kim, K. W.; Kim, H. R.; Choi, H. J.
10.1101/2023.10.01.560411 — neuroscience — Posted on 2023-10-14
2676 Correlated signatures of social behavior in cerebellum and anterior cingulate cortex
Hur, S. W.; Safaryan, K.; Yang, L.; Blair, H. T.; Masmanidis, S. C.; Mathews, P. J.; Aharoni, D.; Golshani, P.
10.1101/2023.04.05.535750 — neuroscience — Posted on 2023-10-14
2678 Representations of information value in mouse orbitofrontal cortex during information seeking
Bussell, J. J.; Badman, R. P.; Marton, C. D.; Bromberg-Martin, E. S.; Abbott, L.; Rajan, K.; Axel, R.
10.1101/2023.10.13.562291 — neuroscience — Posted on 2023-10-13
2679 Age, sex, and cell type-resolved hypothalamic gene expression across the pubertal transition in mice
Sokolowski, D. J.; Hou, H.; Yuki, K. E.; Roy, A.; Chan, C.; Faykoo-Martinez, M.; Hudson, M.; Uuskula-Reimand, L.; Goldenberg, A.; Palmert, M. R.; Wilson, M. D.
10.1101/2023.10.12.562121 — genomics — Posted on 2023-10-13
2684 Programmable delivery of fluoxetine via wearable bioelectronics for wound healing in vivo
Li, H.; Yang, H.-y.; Asefifeyzabadi, N.; Baniya, P.; Zlobina, K.; Hsieh, H.-C.; Nguyen, T.; Hernandez, C.; Carrion, H.; Tebyani, M.; Selberg, J.; Gomez, M.; Teodorescu, M.; Lopez, A. M.; Gallegos, A.; Zhu, K.; Recendez, C.; Luo, L.; Alhamo, M. A.; Norouzi, N.; Soulika, A. M.; Levin, M.; Zhao, M.; Isseroff, R. R.; Rolandi, M.
10.1101/2023.10.10.561754 — bioengineering — Posted on 2023-10-13
2687 Alkaline and loess grasslands with contrasting richness and biomass patterns are not separated on the CSR strategy spectrum.
McIntosh-Buday, A.; Sonkoly, J.; Molnar, A.; Szel-Toth, K.; Toro-Szijgyarto, V.; Madar, S.; Karolyi, E.; Diaz Cando, P. E.; Kovacsics-Vari, G.; Tothmeresz, B.; Torok, P.
10.1101/2023.10.10.561704 — ecology — Posted on 2023-10-13
2689 Microbiota-dependent indole production is required for the development of collagen-induced arthritis
Seymour, B.; Trent, B.; Allen, B.; Berlinberg, A.; Tangchittsumran, J.; Jubair, W.; Chriswell, M.; Liu, S.; Ornelas Sanchez, A.; Stahly, A.; Alexeev, E.; Dowdell, A.; Sneed, S.; Fechtner, S.; Kofonow, J.; Robertson, C.; Dillon, S.; Wilson, C.; Anthony, R.; Frank, D.; Colgan, S.; Kuhn, K. A.
10.1101/2023.10.13.561693 — immunology — Posted on 2023-10-13
2693 Arrayed in vivo barcoding for multiplexed sequence verification of plasmid DNA and demultiplexing of pooled libraries
Li, W.; Miller, D.; Liu, X.; Tosi, L.; Chkaiban, L.; Mei, H.; Hung, P.-H.; Parekkadan, B.; Sherlock, G.; Levy, S. F.
10.1101/2023.10.13.562064 — synthetic biology — Posted on 2023-10-13
2694 Uncovering the hidden mechanisms of giant unilamellar vesicle formation in cDICE
Van de Cauter, L.; Jawale, Y. K.; Tam, D.; Baldauf, L.; van Buren, L.; Koenderink, G. H.; Dogterom, M.; Ganzinger, K. A.
10.1101/2023.10.13.562183 — synthetic biology — Posted on 2023-10-13
2697 Multiomics-assisted characterization of rice-Yellow Stem Borer interaction provides genomic and mechanistic insights into stem borer tolerance in rice
CG, G.; Bangale, U.; Balija, V.; Ballichatla, S.; Potupureddi, G.; Varma, P.; Magar, N.; J, K.; M, S.; A.P., P.; Laha, G. S.; LV, S. R.; Barbadikar, K. M.; Raman, M. S.; Patel, H. K.; Maganti, S. M.; Sonti, R. V.
10.1101/2023.10.10.561791 — plant biology — Posted on 2023-10-13
2698 Mesenchymal-specific Alms1 knockout in mice recapitulates key metabolic features of Alström Syndrome
McKay, E. J.; Luijten, I.; Weng, X.; Martinez de Morentin, P. B.; De Frutos Gonzalez, E.; Gao, Z.; Kolonin, M. G.; Heisler, L. K.; Semple, R. K.
10.1101/2023.10.12.562074 — physiology — Posted on 2023-10-13
2701 MurSS: Multi-resolution Selective Segmentation Model for Breast Cancer
Lee, J.; Lee, G.; Kwak, T.-Y.; Kim, S.; Jin, M.-S.; Kim, C.; Chang, H.
10.1101/2023.10.10.561807 — bioinformatics — Posted on 2023-10-13
2703 The DeMixSC deconvolution framework uses single-cell sequencing plus a small benchmark dataset for improved analysis of cell-type ratios in complex tissue samples
Guo, S.; Liu, X.; Cheng, X.; Jiang, Y.; Ji, S.; Liang, Q.; Koval, A.; Li, Y.; Owen, L. A.; Kim, I. K.; Aparicio, A.; Weinstein, J. N.; Kopetz, S.; DeAngelis, M. M.; Chen, R.; Wang, W.
10.1101/2023.10.10.561733 — bioinformatics — Posted on 2023-10-13
2705 The V-ATPase-ATG16L1 axis recruits LRRK2 to facilitate lysosomal stress responses
Eguchi, T.; Sakurai, M.; Wang, Y.; Saito, C.; Yoshii, G.; Wileman, T.; Mizushima, N.; Kuwahara, T.; Iwatsubo, T.
10.1101/2023.10.13.562167 — molecular biology — Posted on 2023-10-13
2708 Antiviral and Antibacterial Efficacy of Nanocomposite Amorphous Carbon Films with Copper Nanoparticles
Bakhet, S.; Tamuleviciene, A.; Vasiliauskas, A.; Meskinis, S.; Tamulevicius, S.; Kasetiene, N.; Malakauskas, M.; Lelesius, R.; Zienius, D.; Salomskas, A.; Tamulevicius, T.
10.1101/2023.10.13.562202 — microbiology — Posted on 2023-10-13
2709 Chikungunya virus infection disrupts lymph node lymphatic endothelial cell composition and function via MARCO
Lucas, C.; Sheridan, R.; Reynoso, G.; Davenport, B.; McCarthy, M.; Martin, A.; Hesselberth, J.; Hickman, H.; Tamburini, B.; Morrison, T.
10.1101/2023.10.12.561615 — immunology — Posted on 2023-10-13
2710 The human microglia responsome: a resource to better understand microglia states in health and disease
Snijders, G.; de Paiva Lopes, K.; Sneeboer, M.; Muller, B.; Gigase, F.; Vialle, R.; Missall, R.; Kubler, R.; Raj, T.; Humphrey, J.; de Witte, L.
10.1101/2023.10.12.562067 — neuroscience — Posted on 2023-10-13
2711 Effects of hippocampal noninvasive theta-burst stimulation on consolidation of associative memory in healthy older adults
Popa, T.; Beanato, E.; Wessel, M. J.; Menoud, P.; Windel, F.; Vassiliadis, P.; Violante, I. R.; Alania, K.; Dzialecka, P.; Grossman, N.; Neufeld, E.; Hummel, F. C.
10.1101/2023.10.11.554933 — neuroscience — Posted on 2023-10-13
2713 Cardiac-sympathetic contractility and neural alpha-band power: cross-modal collaboration during approach-avoidance conflict
Dundon, N. M.; Stuber, A.; Bullock, T.; Garcia, J. O.; Babenko, V.; Rizor, E.; Yang, D.; Giesbrecht, B.; Grafton, S. T.
10.1101/2023.10.10.561785 — physiology — Posted on 2023-10-13
2714 sincFold: end-to-end learning of short- and long-range interactions for RNA folding
Bugnon, L. A.; Di Persia, L.; Gerard, M.; Raad, J.; Prochetto, S.; Fenoy, E.; Chorostecki, U.; Ariel, F.; Stegmayer, G.; Milone, D. H.
10.1101/2023.10.10.561771 — bioinformatics — Posted on 2023-10-13
2715 Mapping the topography of spatial gene expression with interpretable deep learning
Chitra, U.; Arnold, B. J.; Sarkar, H.; Ma, C.; Lopez-Darwin, S.; Sanno, K.; Raphael, B. J.
10.1101/2023.10.10.561757 — bioinformatics — Posted on 2023-10-13
2717 ViCEKb: Vitiligo-linked Chemical Exposome Knowledgebase
Chivukula, N.; Ramesh, K.; Subbaroyan, A.; Sahoo, A. K.; Dhanakoti, G. B.; Ravichandran, J.; Samal, A.
10.1101/2023.10.10.561820 — bioinformatics — Posted on 2023-10-13
2719 Structure of the endosomal CORVET tethering complex
Shvarev, D.; Koenig, C.; Susan, N.; Langemeyer, L.; Walter, S.; Perz, A.; Froehlich, F.; Ungermann, C.; Moeller, A.
10.1101/2023.10.13.562242 — biochemistry — Posted on 2023-10-13
2720 Activation of automethylated PRC2 by dimerization on chromatin
Sauer, P. V.; Pavlenko, E.; Cookis, T.; Zirden, L. C.; Renn, J.; Singhal, A.; Hunold, P.; Hoehne, M. N.; van Ray, O.; Haensel-Hertsch, R.; Sanbonmatsu, K. Y.; Nogales, E.; Poepsel, S.
10.1101/2023.10.12.562141 — biochemistry — Posted on 2023-10-13
2721 Fibril Paint to detect Amyloids and determine Fibril Length
Aragones Pedrola, J.; Dekker, F. A.; Garfagnini, T.; Mayer, G.; Koopman, M. B.; Bergmeijer, M.; Forster, F.; Hoozemans, J. J.; Jensen, H.; Friedler, A.; Rudiger, S. G.
10.1101/2023.10.13.562220 — biochemistry — Posted on 2023-10-13
2724 Deep Mutational Scanning in Rare Disease-related Genes with Saturation Mutagenesis-Reinforced Functional Assays (SMuRF)
Ma, K.; Ng, K. K.; Huang, S.; Lake, N. J.; Xu, J.; Ge, L.; Woodman, K. G.; Koczwara, K. E.; Lek, A.; Lek, M.
10.1101/2023.07.12.548370 — genetics — Posted on 2023-10-13
2725 Quantifying massively parallel microbial growth with spatially mediated interactions
Borse, F.; Kiciatovas, D.; Kuosmanen, T.; Vidal, M.; Cabrera-Vives, G.; Cairns, J.; Warringer, J.; Mustonen, V.
10.1101/2023.10.10.561814 — ecology — Posted on 2023-10-13
2726 Engineered dsRNA-protein nanoparticles for effective long-distance transport, delivery and gene silencing in plants
Sun, H.; Kalluri, A.; Tang, D.; Ding, J.; Zhai, L.; Gu, X.; Li, Y.; Yer, H.; Yang, X.; Tuskan, G. A.; Deng, Z.; Gmitter, F.; Duan, H.; Kumar, C.; Li, Y.
10.1101/2023.10.12.562099 — molecular biology — Posted on 2023-10-13
2727 The ribonucleoprotein-mediated CRISPR-Cas9 system induces recurrent Aire gene mutations in contrast to the nickase expression vector in murine in vitro or in vivo models
Tanaka, P. P.; Monteiro, C. J.; Duarte, M. J.; Oliveira, E. H.; Monteleone-Cassiano, A. C.; Mascarenhas, R. S.; Machado, M. C.; Matos, A. A.; Brito, L. A.; Ozorio, A. O.; Cunha, T. M.; Donadi, E. A.; Passos, G. A.
10.1101/2023.10.13.562266 — molecular biology — Posted on 2023-10-13
2729 Interleukin 11-induced microRNAs as functional mediators and circulating biomarkers of cardiac fibrosis
Tikhomirov, R.; Reilly-O'Donnell, B.; Lucarelli, C.; Srivastava, P. K.; Anwar, M.; Yiu, C. H. K.; Dielesen, J.; Piella, S. N.; Kwan, Z.; Zaccagnini, G.; Mansfield, C.; Tessari, M.; Menicanti, L. A.; Greco, S.; Leszek, P.; Faggian, G.; Emanueli, C.; Martelli, F.; Gorelik, J.
10.1101/2023.10.11.561968 — molecular biology — Posted on 2023-10-13
2730 Biosynthesis of the azoxy compound azodyrecin from Streptomyces mirabilis P8-A2
Maleckis, M.; Wibowo, M.; Gren, T.; Jarmusch, S. A.; Sterndorff, E. B.; Booth, T. J.; Henriksen, N. N. S. E.; Whitford, C. M.; Jiang, X.; Jorgensen, T. S.; Ding, L.; Weber, T.
10.1101/2023.10.13.562208 — microbiology — Posted on 2023-10-13
2733 Characterization of Ralstonia pseudosolanacearum diversity and screening host resistance to manage bacterial wilt in South Asia
Subedi, N.; Cowell, T.; Cope-Arguello, M.; Paul, P.; Cellier, G.; Bkayrat, H.; Bonagura, N.; Catadal, A.; Chen, R.; Enriquez, A.; Parasar, R.; Repetto, L.; Hernandez Rivas, A.; Shahbaz, M.; White, K.; Lowe-Power, T. M.; Miller, S. A.
10.1101/2023.10.13.559983 — microbiology — Posted on 2023-10-13
2734 N6-methyladenosine modification is not a general trait of viral RNA genomes
Baquero-Perez, B.; Yonchev, I. D.; Delgado-Tejedor, A.; Medina, R.; Puig-Torrents, M.; Sudbery, I. M.; Begik, O.; Wilson, S. A.; Novoa, E. M.; Diez, J.
10.1101/2023.10.13.561839 — microbiology — Posted on 2023-10-13
2735 Genetically refactored Agrobacterium-mediated transformation
Thompson, M.; Kirkpatrick, L. D.; Geiselman, G. M.; Waldburger, L. M.; Pearson, A. N.; Szarzanowicz, M.; Vuu, K. M.; Markel, K.; Hummel, N. F.; Suazo, D. D.; Tahmin, C.; Cui, R.; Liu, S.; Cevallos, J.; Pannu, H.; Liu, D.; Gin, J. W.; Chen, Y.; Petzold, C. J.; Gladden, J.; Keasling, J. D.; Chang, J. H.; Weisberg, A. J.; Shih, P. M.
10.1101/2023.10.13.561914 — microbiology — Posted on 2023-10-13
2737 Using the pan-genomic framework for the discovery of genomic islands in the haloarchaeon Halorubrum ezzemoulense
Feng, Y.; Arsenault, D.; Louyakis, A. S.; Altman-Price, N.; Gophna, U.; Papke, R. T.; Gogarten, J. P.
10.1101/2023.10.13.561781 — microbiology — Posted on 2023-10-13
2739 Human pluripotent stem cell-derived hepatocyte-like cells for hepatitis D virus studies
Chi, H.; Qu, B.; Prawira, A.; Maurer, L.; Hu, J.; Fu, R. M.; Lempp, F. A.; Zhang, Z.; Grimm, D.; Wu, X.; Urban, S.; Dao Thi, V. L.
10.1101/2023.10.13.561984 — microbiology — Posted on 2023-10-13
2740 A ubiquitous Microcoleus species causes benthic cyanotoxic blooms worldwide
Junier, P.; Cailleau, G.; Fatton, M.; Udriet, P.; Hashmi, I.; Bregnard, D.; Corona-Ramirez, A.; de Francesco, E.; Kuhn, T.; Mangia, N.; Zhioua, S.; Hunkeler, D.; Bindschedler, S.; Sieber, S.; Gonzalez, D.
10.1101/2023.10.13.562201 — microbiology — Posted on 2023-10-13
2741 Cytotoxic rhamnolipid micelles drive acute virulence in Pseudomonas aeruginosa
Xu, Q.; Kang, D.; Meyer, M. D.; Pennington, C. L.; Gopal, C.; Schertzer, J. W.; Kirienko, N.
10.1101/2023.10.13.562257 — microbiology — Posted on 2023-10-13
2742 Ultrasensitive allele inference from immune repertoire sequencing data with MiXCR
Mikelov, A.; Nefedev, G.; Tashkeev, A.; Rodriguez, O. L.; Ortmans, D. A.; Skatova, V.; Izraelson, M.; Davydov, A.; Poslavsky, S.; Rahmouni, S.; Watson, C. T.; Chudakov, D.; Boyd, S. D.; Bolotin, D. A.
10.1101/2023.10.10.561703 — immunology — Posted on 2023-10-13
2745 NMR analysis of the homodimeric structure of a D-Ala-D-Ala metallopeptidase, VanX, from vancomycin-resistant bacteria
Konuma, T.; Takai, T.; Tsuchiya, C.; Nishida, M.; Hashiba, M.; Yamada, Y.; Shirai, H.; Nagadoi, A.; Chikaishi, E.; Akagi, K.-i.; Akashi, S.; Yamazaki, T.; Akutsu, H.; Ikegami, T.
10.1101/2023.10.13.562161 — biochemistry — Posted on 2023-10-13
2746 Nanobodies against SARS-CoV-2 non-structural protein Nsp9 inhibit viral replication by targeting innate immunity
Venit, T.; Blavier, J.; Maseko, S. B.; Shu, S.; Espada, L.; Breunig, C.; Holthoff, H.-P.; Desbordes, S. C.; Lohse, M.; Esposito, G.; Twizere, J.-C.; Percipalle, P.
10.1101/2023.10.12.561992 — cell biology — Posted on 2023-10-13
2747 Akaluc bioluminescence offers superior sensitivity to track in vivo dynamics of SARS-CoV-2 infection
Tamura, T.; Ito, H.; Torii, S.; Wang, L.; Tsujino, S.; Kamiyama, A.; Oda, Y.; Morioka, Y.; Suzuki, S.; Shirakawa, K.; Sato, K.; Yoshimatsu, K.; Matsuura, Y.; Iwano, S.; Tanaka, S.; Fukuhara, T.
10.1101/2023.10.12.561993 — microbiology — Posted on 2023-10-13
2748 TreePPL: A Universal Probabilistic Programming Language for Phylogenetics
Senderov, V. E.; Kudlicka, J.; Lunden, D.; Palmkvist, V.; Braga, M. P.; Granqvist, E.; Broman, D.; Ronquist, F. E.
10.1101/2023.10.10.561673 — bioinformatics — Posted on 2023-10-13
2752 Reference materials for SARS-CoV-2 molecular diagnostic quality control: validation of encapsulated synthetic RNAs for room temperature storage and shipping
Colotte, M.; Luis, A.; Coudy, D.; Tuffet, S.; Robene, I.; Fenelon, B.; Jouen, E.; Leveque, N.; Deroche, L.; Busson, L.; Alain, S.; Plumelle, D.; Tumiotto, C.; Lafon, M.-E.; Bonnet, J.
10.1101/2023.08.28.555008 — molecular biology — Posted on 2023-10-13
2754 Cognitive Reserve Against Alzheimer's Pathology Is Linked to Brain Activity During Memory Formation
Vockert, N.; Machts, J.; Kleineidam, L.; Nemali, A.; Schutze, H.; Yakupov, R.; Peters, O.; Gref, D.; Schneider, L. S.; Preis, L.; Priller, J.; Spruth, E. J.; Altenstein, S.; Schneider, A.; Fliessbach, K.; Wiltfang, J.; Rostamzadeh, A.; Glanz, W.; Incesoy, E.; Teipel, S.; Kilimann, I.; Goerss, D.; Laske, C.; Munk, M. H.; Spottke, A.; Roy, N.; Heneka, M. T.; Brosseron, F.; Wagner, M.; Wolfsgruber, S.; Dobisch, L.; Dechent, P.; Hetzer, S.; Scheffler, K.; Zeidman, P.; Stern, Y.; Schott, B. H.; Jessen, F.; Duzel, E.; Maass, A.; Ziegler, G.; the DELCODE study group,
10.1101/2023.10.10.561675 — neuroscience — Posted on 2023-10-13
2755 Behavioral Thermoregulation in Captive Fish: Molecular, Physiological, and Welfare Implications
Sanhueza, N.; Fuentes, R.; Aguilar, A.; Carnicero, B.; Mattos, H.; Rubalcaba, Y.; Melin, V.; Contreras, D.; Boltana, S.
10.1101/2023.10.10.561692 — physiology — Posted on 2023-10-13
2758 Computational Design of a Highly-Specific HVEM-Based Inhibitor of LIGHT Protein
Ciura, P.; Smardz, P.; Krupa, M.; Spodzieja, M.; Krupa, P.; Sieradzan, A. K.
10.1101/2023.10.10.561657 — bioinformatics — Posted on 2023-10-13
2759 CHRONO participates in multi-modal repression of circadian transcriptional complexes
Crosby, P.; Goularte, N. F.; Sharma, D.; Chen, E.; Parico, G. C. G.; Philpott, J. M.; Harold, R.; Gustafson, C. L.; Partch, C. L.
10.1101/2022.10.04.510902 — biochemistry — Posted on 2023-10-13
2761 A likelihood-based framework for demographic inference from genealogical trees
Fan, C.; Cahoon, J. L.; Dinh, B. L.; Ortega-Del Vecchyo, D.; Huber, C. D.; Edge, M. D.; Mancuso, N.; Chiang, C. W. K.
10.1101/2023.10.10.561787 — genetics — Posted on 2023-10-13
2764 CCR5 promotes the migration of CD8+ T cells to the leishmanial lesions
Amorim Sacramento, L.; Farias Amorim, C.; G. Lombana, C.; Beiting, D.; Novais, F.; Carvalho, L. P. d.; M. Carvalho, E.; Scott, P.
10.1101/2023.10.10.561700 — immunology — Posted on 2023-10-13
2766 Aβ-affine bifunctional copper chelators capable of Aβ-induced oxidative stress reduction and amyloid disaggregation
Krasnovskaya, O. O.; Abramchuk, D.; Vaneev, A.; Gorelkin, P.; Abakumov, M.; Timoshenko, R.; Chmelyuk, N.; Vadehina, V.; Kuanaeva, R.; Dubrovin, E. V.; Kolmogorov, V.; Beloglazkina, E. K.; Erofeev, A. S.
10.1101/2023.10.10.561649 — pharmacology and toxicology — Posted on 2023-10-13
2767 p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response
Serra, F.; Nieto-Aliseda, A.; Fanlo, L.; Rovirosa, L.; Cabrera-Pasadas, M.; Lazarenkov, A.; Urmeneta, B.; Alcalde, A.; Nola, E. M.; Okorokov, A. L.; Fraser, P.; Graupera, M.; Castillo, S. D.; Sardina, J. L.; Valencia, A.; Javierre, B. M.
10.1101/2023.10.10.561663 — genomics — Posted on 2023-10-13
2768 Monitoring Resilience in Bursts
Delecroix, C.; van Nes, E. H.; Scheffer, M.; van de Leemput, I. A.
10.1101/2023.10.10.561665 — ecology — Posted on 2023-10-13
2771 Chromosome 8 gain drives cancer progression by hijacking the translation factor 4E-BP1 sensitizing for targeted CDK4/6 inhibition
Funk, C. M.; Ehlers, A.; Orth, M. F.; Aljakouch, K.; Li, J.; Hoelting, T. L. B.; Will, R.; Willis, F.; Vinca, E.; Ohmura, S.; Imle, R.; Siebenlist, J.; Knott, M. M. L.; Zahnow, F.; Sastre, A.; Alonso, J.; Sahm, F.; Loboda, A.; Peterziel, H.; Schneider, M.; Banito, A.; Leprivier, G.; Hartmann, W.; Dirksen, U.; Witt, O.; Oehme, I.; Pfister, S. M.; Romero-Perez, L.; Krijgsveld, J.; Cidre-Aranaz, F.; Gruenewald, T. G. P.; Musa, J.
10.1101/2022.12.11.519935 — cancer biology — Posted on 2023-10-13
2773 Detection of a historic reservoir of bedaquiline 1 / clofazimine resistance associated variants in Mycobacterium tuberculosis
Nimmo, C.; Torres Ortiz, A.; Pang, J.; Acman, M.; Tan, C. C.; Millard, J.; Padayatchi, N.; Grant, A.; O'Donnell, M. R.; Pym, A.; Brynildsrud, O. B.; Eldholm, V.; Grandjean, L.; Didelot, X.; Balloux, F.; van Dorp, L.
10.1101/2020.10.06.328799 — genomics — Posted on 2023-10-13
2779 The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer's disease
Ribeiro, F. C.; Cozachenco, D.; Argyrousi, E. K.; Staniszewski, A.; Wiebe, S.; Calixtro, J. D.; Soares-Neto, R.; Al-Chami, A.; El Sayegh, F.; Bermudez, S.; Arsenault, E.; Cossenza, M.; Lacaille, J.-C.; Nader, K.; Sun, H.; De Felice, F. G.; Lourenco, M. V.; Arancio, O.; Aguilar-Valles, A.; Sonenberg, N.; Ferreira, S. T.
10.1101/2023.08.03.551808 — neuroscience — Posted on 2023-10-13
2781 Pharmacological characterization and radiolabeling ofVUF15485, a high-affinity small-molecule agonist for theatypical chemokine receptor ACKR3
Zarca, A.; Adlere, I.; Viciano, C. P.; Arimont-Segura, M.; Meyrath, M.; Simon, I. A.; Bebelman, J. P. M.; Laan, D.; Custers, H. G. J.; Janssen, E. C.; Versteegh, K. L.; Bosma, R.; De Esch, I. J. P.; Vischer, H. F.; Wijtmans, M.; Szpakowska, M.; Chevigne, A.; Hoffmann, C.; de Graaf, C.; Zarzycka, B. A.; Windhorst, A. D.; Smit, M. J.; Leurs, R.
10.1101/2023.07.12.548622 — pharmacology and toxicology — Posted on 2023-10-13
2782 Rational Prediction of PROTAC-compatible Protein-Protein Interfaces by Molecular Docking
Pereira, G. P.; Garcia, B. J.; Pellarin, R.; Launay, G.; Wu, S.; Martin, J.; de Souza, P. C. T.
10.1101/2023.02.16.528819 — bioinformatics — Posted on 2023-10-13
2784 Emergent remote stress-focusing drive submucosal collagen fiber remodeling in intestinal anastomotic surgery
Fleischer, B.; Nguyen, N.; Pal, A.; Kim, J.; Khabaz, K.; Tsamis, A.; Efrati, E.; Witten, T.; Alverdy, J.; Pocivavsek, L.
10.1101/2022.10.31.514540 — bioengineering — Posted on 2023-10-13
2786 Experience transforms animals' perspective of the energy landscape
Nourani, E.; Faure, L.; Bronnvik, H.; Scacco, M.; Bassi, E.; Fiedler, W.; Gruebler, M. U.; Hatzl, J.; Jenny, D.; Roverselli, A.; Sumasgutner, P.; Tschumi, M.; Wikelski, M.; Safi, K.
10.1101/2023.09.07.556633 — animal behavior and cognition — Posted on 2023-10-13
2787 Comparative population genomics of manta rays has global implications for management
Humble, E.; Hosegood, J.; Carvalho, G.; de Bruyn, M.; Creer, S.; Stevens, G. M. W.; Armstrong, A.; Bonfil, R.; Deakos, M.; Fernando, D.; Froman, N.; Peel, L. R.; Pollett, S.; Ponzo, A.; Poquita, A. L.; Stewart, J. D.; Wintner, S.; Ogden, R.
10.1101/2023.06.19.545572 — evolutionary biology — Posted on 2023-10-13
2790 Distinct functions for the paralogous RBM41 and U11/U12-65K proteins in the minor spliceosome
Norppa, A. J.; Chowdhury, I.; van Rooijen, L. E.; Ravantti, J. J.; Snel, B.; Varjosalo, M.; Frilander, M. J.
10.1101/2023.10.12.562036 — molecular biology — Posted on 2023-10-13
2791 TopBP1 utilises a bipartite GINS binding mode to support genome replication
Day, M.; Tetik, B.; Parlak, M.; Almeida-Hernandez, Y.; Raeschle, M.; Kaschani, F.; Siegert, H.; Marko, A.; Sanchez-Garcia, E.; Kaiser, M.; Barker, I.; Pearl, L. H.; Oliver, A.; Boos, D.
10.1101/2023.03.31.535063 — molecular biology — Posted on 2023-10-13
2792 TCR Repertoire Analysis of CD4-Positive T Cells from Blood and an Affected Organ in an Autoimmune Mouse Model
Ishikawa, T.; Horie, K.; Takakura, Y.; Ohki, H.; Maruyama, Y.; Hayama, M.; Miyauchi, M.; Miyao, T.; Hagiwara, N.; Kobayashi, T. J.; Akiyama, N.; Akiyama, T.
10.1101/2023.03.08.531799 — immunology — Posted on 2023-10-13
2793 Balance of Activity during a Critical Period Tunes a Developing Network
Hunter, I.; Coulson, B.; Pettini, T.; Davies, J. J.; Parkin, J.; Landgraf, M.; Baines, R. A.
10.1101/2023.08.04.551972 — neuroscience — Posted on 2023-10-13
2795 Phosphorylation Promotes DELLA Activity by Enhancing Its Binding to Histone H2A at Target Chromatin in Arabidopsis
Huang, X.; Zentella, R.; Park, J.; Reser, L.; Bai, D.; Ross, M.; Shabanowitz, J.; Hunt, D.; Sun, T.-p.
10.1101/2023.10.10.561786 — plant biology — Posted on 2023-10-13
2796 Comparison of polystyrene and hydrogel microcarriers for optical imaging of adherent cells
Benavides, O. R.; White, B. P.; Gibbs, H. C.; Kaunas, R.; Gregory, C. A.; Maitland, K. C.; Walsh, A. J.
10.1101/2023.10.12.559796 — biophysics — Posted on 2023-10-13
2797 CLN3 transcript complexity revealed by long-read RNA sequencing analysis
Zhang, H.-Y.; Minnis, C.; Gustavsson, E. K.; Ryten, M.; Mole, S. E.
10.1101/2023.10.12.562062 — genetics — Posted on 2023-10-13
2800 Anti-adipogenic properties of clock activator chlorhexidine and a new derivative
Xiong, X.; Kiperman, T.; Li, W.; Fang, Z.; Agua, A.; Huang, W.; Horne, D.; Ma, K.
10.1101/2023.10.12.562086 — cell biology — Posted on 2023-10-13
2804 Interaction of GAT1 with sodium ions: from efficient recruitment to stabilisation of substrate and conformation
Lazzarin, E.; Gradisch, R.; Skopec, S. M.; Alves da Silva, L.; Szollosi, D.; Maier, J.; Sucic, S.; Kanner, B.; Sitte, H. H.; Stockner, T.
10.1101/2023.10.10.561652 — molecular biology — Posted on 2023-10-13
2805 An exploration of mechanisms underlying Desemzia incerta colonization resistance to methicillin-resistant Staphylococcus aureus on the skin
Wei, M.; Knight, S. A. B.; Fazelinia, H.; Spruce, L.; Roof, J.; Chu, E. W.; Walsh, J.; Flowers, L.; Kim, D. Y.; Zhu, J.; Grice, E. A.
10.1101/2023.10.11.561853 — microbiology — Posted on 2023-10-13
2811 Molecular and metabolomic characterization of hiPSC-derived cardiac fibroblasts transitioning to myofibroblasts
Nagalingam, R.; Jayousi, F.; Hamledari, H.; Hosseini Baygi, D.; Dababneh, S.; Lindsay, C.; Dixon, I. M. C.; Klein Geltink, R.; Lange, P.; Rose, R. A.; Czubryt, M. P.; Tibbits, G. F.
10.1101/2023.10.08.561455 — cell biology — Posted on 2023-10-13
2815 Mast-Cell Expressed Membrane Protein-1 (MCEMP1) is expressed in classical monocytes and alveolar macrophages in Idiopathic Pulmonary Fibrosis and regulates cell chemotaxis, adhesion, and migration in a TGFβ dependent manner.
Perrot, C. Y.; Karampitsakos, T.; Unterman, A.; Adams, T.; Marlin, K.; Arsenault, A.; Zhao, A.; Kaminski, N.; Katlaps, G.; Patel, K.; Bandyopadhyay, D.; Herazo-Maya, J. D.
10.1101/2023.10.07.561349 — immunology — Posted on 2023-10-13
2816 Coding dynamics of the striatal networks during learning
Villet, M.; Reynaud-Bouret, P.; Poitreau, J.; Baldi, J.; Jaffard, S.; James, A.; Muzy, A.; Sargolini, F.; Bethus, I.
10.1101/2023.07.24.550305 — neuroscience — Posted on 2023-10-13
2817 Ependymocytes control cerebrospinal fluid flow to the peripheral organs through periaxonal pathway
Li, X.; Wang, S.; Zhang, D.; Feng, Y.; Liu, Y.; Yu, W.; Li, S.; Cui, L.; Harkany, T.; Verkhratsky, A.; Xia, M.; Li, B.
10.1101/2023.10.09.560634 — neuroscience — Posted on 2023-10-13
2818 Woolly mutation with Get02 locus overcomes the polygenic nature of trichome-based pest resistance in tomato
VENDEMIATTI, E.; Hernandez-De Lira, I. O.; Snijders, R.; Torne, T.; Therezan, R.; Simioni Prants, G.; Lopez-Ortiz, C.; Reddy, U.; Bleeker, P.; Schenck, C.; Peres, L. E. P.; Benedito, V. A.
10.1101/2023.10.06.561305 — plant biology — Posted on 2023-10-13
2819 Myeloperoxidase activity predicts atherosclerotic plaque disruption and atherothrombosis
Nadel, J.; Wang, X.; Saha, P.; Bongers, A.; Tumanov, S.; Giannotti, N.; Chen, W.; Vidger, N.; Chowdhury, M. M.; Lima da Cruz, G. J.; Velasco, C.; Prieto, C.; Jabbour, A.; Botnar, R. M.; Stocker, R.; Phinikaridou, A.
10.1101/2023.10.08.561454 — biochemistry — Posted on 2023-10-13
2823 The International Weed Genomics Consortium: Community Resources for Weed Genomics Research
Montgomery, J. S.; Morran, S.; MacGregor, D. R.; McElroy, J. S.; Neve, P.; Neto, C.; Vila-Aiub, M. M.; Sandoval, M. V.; Menendez, A. I.; Kreiner, J.; Fan, L.; Caicedo, A. L.; Maughan, P. J.; Martins, B. A. B.; Mika, J.; Collavo, A.; Merotto, A.; Subramanian, N. K.; Bagavathiannan, M. V.; Cutti, L.; Islam, M. M.; Gill, B. S.; Cicchillo, R.; Gast, R.; Soni, N.; Wright, T. R.; Zastrow-Hayes, G.; May, G.; Malone, J. M.; Sehgal, D.; Kaundun, S. S.; Dale, R. P.; Vorster, B. J.; Peters, B.; Lerchl, J.; Tranel, P. J.; Beffa, R.; Fournier-Level, A.; Jugulam, M.; Fengler, K.; Llaca, V.; Patterson, E. L.
10.1101/2023.07.19.549613 — genomics — Posted on 2023-10-12
2825 Neuronal "parts list" and wiring diagram for a visual system
Matsliah, A.; Yu, S.-c.; Kruk, K.; Bland, D.; Burke, A.; Gager, J.; Hebditch, J.; Silverman, B.; Willie, K.; Willie, R.; Sorek, M.; Sterling, A. R.; Kind, E.; Garner, D.; Sancer, G.; Wernet, M.; Kim, S. S.; Murthy, M.; Seung, H. S.; FlyWire Consortium,
10.1101/2023.10.12.562119 — neuroscience — Posted on 2023-10-13
2826 Remyelination protects neurons from DLK-mediated neurodegeneration
Duncan, G. J.; Ingram, S. D.; Emberley, K.; Hill, J.; Cordano, C.; Abdelhak, A.; McCane, M.; Jabassini, N.; Ananth, K.; Ferrara, S. J.; Stedelin, B.; Sivyer, B.; Aicher, S. A.; Watkins, T. A.; Mishra, A.; Nelson, J.; Green, A. J.; Emery, B.
10.1101/2023.09.30.560267 — neuroscience — Posted on 2023-10-12
2827 Decrypting the languages of allostery in membrane-bound K-Ras4B using four complementary in silico approaches
Castelli, M.; Marchetti, F.; Osuna, S.; F. Oliveira, A. S.; Mulholland, A. J.; Serapian, S. A.; Colombo, G.
10.1101/2023.07.14.549022 — biochemistry — Posted on 2023-10-12
2829 Neurovirulence of the Australian outbreak Japanese Encephalitis virus genotype 4 is lower compared to genotypes 2 and 3 in mice and human cortical brain organoids
Nguyen, W.; Gyawali, N.; Stewart, R.; Tang, B.; Cox, A. L.; Yan, K.; Larcher, T.; Bishop, C. R.; Wood, N.; Devine, G.; Suhrbier, A.; Rawle, D. J.
10.1101/2023.04.26.538504 — microbiology — Posted on 2023-10-12
2830 Dysfunctional T Follicular Helper Cells Cause Intestinal and Hepatic Inflammation in NASH
Wang, H.; Barrow, F.; Fredrickson, G.; Florczak, K.; Ikramuddin, S.; Ruan, H.-B.; Jameson, S. C.; Revelo, X.
10.1101/2023.06.07.544061 — immunology — Posted on 2023-10-12
2831 Striatal calcium transients detected by fiber photometry propagate to axons
Lipton, D. M.; Tamimi, M.; Shalom, I.; Sheinfeld, T.; Gonzales, B. J.; Groysman, M.; Citri, A.
10.1101/2023.10.09.560813 — neuroscience — Posted on 2023-10-12
2835 The impact of short-term forearm immobilization and acipimox administration on muscle amino acid metabolism and insulin sensitivity in healthy, young volunteers
Dirks, M. L.; Jameson, T. S. O.; Andrews, R. C.; Dunlop, M. V.; Abdelrahman, D. R.; Murton, A. J.; Wall, B. T.; Stephens, F. B.
10.1101/2023.10.10.561668 — physiology — Posted on 2023-10-12
2837 Tricyclic and tetracyclic antidepressants upregulate VMAT2 activity and rescue disease-causing VMAT2 variants
Wang, X.; Marmouzi, I.; Finnie, P. S.; Stove, S. I.; Butcher, M. L.; Lipina, T. V.; Ramsey, A. J.; Miller, G. W.; Salahpour, A.
10.1101/2023.10.09.561601 — pharmacology and toxicology — Posted on 2023-10-12
2839 ONECUT2 Activates Diverse Resistance Drivers of Androgen Receptor-Independent Heterogeneity in Prostate Cancer
Qian, C.; Yang, Q.; Rotinen, M.; Huang, R.; Kim, h.; Gallent, B.; Yan, Y.; Cadaneanu, R. M.; Zhang, B.; Kaochar, S.; Freedland, S. J.; Posadas, E. M.; Ellis, L.; Di Vizio, D.; Morrissey, C.; Nelson, P. S.; Brady, L.; Murali, R.; Campbell, M. J.; Yang, W.; Knudsen, B. S.; Mostaghel, E. A.; Ye, H.; Garraway, I. P.; You, S.; Freeman, M. R.
10.1101/2023.09.28.560025 — cancer biology — Posted on 2023-10-12
2840 The Structural Role of N170 in Substrate-assisted Deacylation in KPC-2 β-Lactamase
Parwana, D.; Gu, J.; Wang, Q.; Bethel, C.; Marshall, E. K.; Hujer, A. M.; Bonomo, R. A.; Haider, S.
10.1101/2023.05.22.541848 — biophysics — Posted on 2023-10-12
2842 Expansion of novel biosynthetic gene clusters from diverse environments using SanntiS
Sanchez Fragoso, J. S.; Rogers, J. D.; Rogers, A. B.; Nassar, M.; McEntyre, J.; Welch, M.; Hollfelder, F.; Finn, R. D.
10.1101/2023.05.23.540769 — bioinformatics — Posted on 2023-10-12
2844 Nanoparticle-Conjugated TLR9 Agonists Improve the Potency, Durability, and Breadth of COVID-19 Vaccines
Ou, B. S.; Baillet, J.; Picece, V. C. T. M.; Gale, E. C.; Powell, A. E.; Saouaf, O. M.; Yan, J.; Nejatfard, A.; Lopez Hernandez, H.; Appel, E.
10.1101/2023.01.02.522505 — bioengineering — Posted on 2023-10-12
2846 An enhancer RNA recruits MLL1 to regulate transcription of Myb
Kim, J.; Diaz, L. F.; Miller, M. J.; Leadem, B.; Krivega, I.; Dean, A.
10.1101/2023.09.26.559528 — cell biology — Posted on 2023-10-12
2847 Distinct functions for the paralogous RBM41 and U11/U12-65K proteins in the minor spliceosome
Norppa, A. J.; Chowdhury, I.; van Rooijen, L. E.; Ravantti, J. J.; Snel, B.; Varjosalo, M.; Frilander, M. J.
10.1101/2023.10.12.562036 — molecular biology — Posted on 2023-10-12
2848 Bacterial pore-forming toxin pneumolysin drives pathogenicity through shed toxin-loaded host extracellular vesicles
Parveen, S.; Bhat, C. V.; Aziz, S.; J, A.; Dutta, A.; Dutta, S.; Show, S.; Sharma, K.; Johnson, J. B.; Nongthomba, U.; Banerjee, A.; Subramanian, K.
10.1101/2023.10.12.561978 — microbiology — Posted on 2023-10-12
2849 Rapid enzymatic detection of Shigatoxin-producing E. coli using fluorescence-labeled oligonucleotide substrates
Ramming, I.; Lang, C.; Hauf, S.; Krueger, M.; Worbs, S.; Peukert, C.; Fruth, A.; Dorner, B. G.; Broenstrup, M.; Flieger, A.
10.1101/2023.10.12.562006 — microbiology — Posted on 2023-10-12
2850 Genome-wide Functional Characterization of Escherichia coli Promoters and Sequence Elements Encoding Their Regulation
Urtecho, G.; Insigne, K.; Tripp, A. D.; Brinck, M.; Lubock, N. B.; Acree, C.; Kim, H.; Chan, T.; Kosuri, S.
10.1101/2020.01.04.894907 — microbiology — Posted on 2023-10-12
2851 Increased circulating CD39+FoxP3+CD4+ regulatory T cells in Early Rheumatoid Arthritis facilitate the antiinflammatory action of methotrexate and associate with the clinical response
Villalba, A.; Nuno, L.; Benito-Miguel, M.; Nieto-Carvalhal, B.; Novella-Navarro, M.; Monjo, I.; Peiteado, D.; Garcia-Carazo, S.; Balsa, A.; Miranda-Carus, M.-E.
10.1101/2023.10.10.561686 — immunology — Posted on 2023-10-12
2853 A sequence context-based germline filter for structural variant calling from tumor samples without paired normal
Chukwu, W.; Lee, S.; Crane, A.; Zhang, S.; Mittra, I.; Imielinski, M.; Beroukhim, R.; Dubois, F.; Dalin, S.
10.1101/2023.10.09.561462 — bioinformatics — Posted on 2023-10-12
2855 Modular multiwell viscoelastic hydrogel platform for two- and three-dimensional cell culture applications
Skelton, M. L.; Gentry, J. L.; Astrab, L. R.; Goedert, J. A.; Earl, E. B.; Pham, E. L.; Bhat, T.; Caliari, S. R.
10.1101/2023.10.09.561449 — bioengineering — Posted on 2023-10-12
2856 Fitness landscape of substrate-adaptive mutations in evolved APC transporters
Karapanagioti, F.; Atlason, U. A.; Slotboom, D. J.; Poolman, B.; Obermaier, S.
10.1101/2023.10.12.562049 — biochemistry — Posted on 2023-10-12
2859 The incidence of movement disorders increases with age and contrasts with subtle and limited neuroimaging abnormalities in argininosuccinic aciduria.
Gurung, S.; Karamched, S.; Perocheau, D. P.; Seunarine, K.; Balwin, T.; Touramanidou, L.; Duff, C.; Elkhateeb, N.; Stepien, K.; Sharma, R.; Morris, A.; Hartley, T.; Crowther, L.; Grunewald, S.; Cleary, M.; Mundy, H.; Chakrapani, A.; Batzios, S.; Davison, J.; Footitt, E.; Tuschl, K.; Lachmann, R.; Murphy, E.; Santra, S.; Uudelepp, M.-L.; Uudelepp, M.-L.; Yeo, M.; Finn, P.; Cavedon, A.; Siddiqui, S.; Rice, L.; Martini, P.; Frassetto, A.; Mills, P.; Gissen, P.; Clayden, J. D.; Clark, C.; Eaton, S.; Kalber, T.; Baruteau, J.
10.1101/2023.10.10.561631 — genetics — Posted on 2023-10-12
2861 Serum-deprivation response of ARPE-19 cells; expression patterns relevant to age-related macular degeneration.
Peterson, K. M.; Mishra, S.; Asaki, E.; Powell, J. I.; He, Y.; Berger, A.; Rajapakse, D.; Wistow, G.
10.1101/2023.10.12.562023 — molecular biology — Posted on 2023-10-12
2862 Partial suppression of BCAA catabolism as a potential therapy for BCKDK deficiency
Ohl, L.; Kuhs, A.; Pluck, R.; Durham, E.; Noji, M.; Philip, N. D.; Arany, Z.; Ahrens-Nicklas, R. C.
10.1101/2023.10.12.560929 — molecular biology — Posted on 2023-10-12
2863 Lipid discovery enabled by sequence statistics and machine learning
Christensen, P. M.; Martin, J.; Uppuluri, A.; Joyce, L. R.; Wei, Y.; Guan, Z.; Morcos, F.; Palmer, K.
10.1101/2023.10.12.562061 — microbiology — Posted on 2023-10-12
2864 Dehydration induced AePer50 regulates midgut infection in Aedes aegypti
Accoti, A.; Becker, M.; Abu, A. E. I.; Vulcan, J.; Yun, R.; Widen, S. G.; Sylla, M.; Popov, V. L.; Weaver, S. C.; Dickson, L. B.
10.1101/2023.10.11.561962 — microbiology — Posted on 2023-10-12
2866 Full genome sequence analysis of African swine fever virus isolates from Cameroon
Goatley, L. C.; Freimanis, G.; Tennakoon, C.; Foster, T. J.; Quershi, M.; Dixon, L. K.; Batten, C.; Forth, J. H.; Wade, A.; Netherton, C.
10.1101/2023.10.11.561033 — microbiology — Posted on 2023-10-12
2870 Accelerated brain change in healthy adults is associated with genetic risk for Alzheimer's disease and uncovers adult lifespan memory decline
Roe, J. M.; Vidal-Pineiro, D.; Sorensen, O.; Grydeland, H.; Leonardsen, E. H.; Iakunchykova, O.; Pan, M.; Mowinckel, A.; Stromstad, M.; Nawijn, L.; Milaneschi, Y.; Andersson, M.; Pudas, S.; Brathen, A. C. S.; Kransberg, J.; Falch, E. S.; Overbye, K.; Kievit, R. A.; Ebmeier, K. P.; Lindenberger, U.; Ghisletta, P.; Demnitz, N.; Boraxbekk, C.-J.; Penninx, B.; Bertram, L.; Nyberg, L.; Walhovd, K. B.; Fjell, A. M.; Wang, Y.
10.1101/2023.10.09.559446 — neuroscience — Posted on 2023-10-12
2872 Sarbecovirus disease susceptibility is conserved across viral and host models
Leist, S. R.; Schaefer, A.; Risemberg, E. L.; Bell, T. A.; Hock, P.; Zweigart, M. R.; Linnertz, C. L.; Miller, D. R.; Shaw, G. D.; Pardo-Manuel de Villena, F.; Ferris, M. T.; Valdar, W.; Baric, R. S.
10.1101/2023.10.11.561544 — genetics — Posted on 2023-10-12
2877 A Latent Clinical-anatomical Dimension Relating Metabolic Syndrome to Brain Morphology - Evidence from a Multivariate Imaging Analysis of 40,087 Individuals
Petersen, M.; Hoffstaedter, F.; Naegele, F. L.; Mayer, C.; Schell, M.; Rimmele, D. L.; Zyriax, B.-C.; Zeller, T.; Kuehn, S.; Gallinat, J.; Fiehler, J.; Twerenbold, R.; Omidvarnia, A.; Patil, K.; Eickhoff, S. B.; Thomalla, G.; Cheng, B.
10.1101/2023.02.22.529531 — neuroscience — Posted on 2023-10-12
2879 Integrative study of skeletal muscle mitochondrial dysfunction in a murine pancreatic cancer-induced cachexia model
Gicquel, T.; Marchiano, F.; Reyes-Castellanos, G.; Audebert, S.; Camoin, L.; Habermann, B. H.; Giannesini, B.; Carrier, A.
10.1101/2022.12.28.522098 — cancer biology — Posted on 2023-10-12
2880 RNA molecules display distinctive organization at nuclear speckles
Paul, S.; Arias, M. A.; Wen, L.; Liao, S. E.; Zhang, J.; Wang, X.; Regev, O.; Fei, J.
10.1101/2022.10.17.512423 — biophysics — Posted on 2023-10-12
2883 Divergent selection for feed efficiency in pigs altered the duodenum transcriptome and DNA methylation profiles, resulting in greater responses to feed intake in the most efficient line
Devailly, G.; Feve, K.; Saci, S.; Sarry, J.; Valiere, S.; Lluch, J.; Bouchez, O.; Ravon, L.; Billon, Y.; Gilbert, H.; Riquet, J.; Beaumont, M.; Demars, J.
10.1101/2022.11.03.515018 — genomics — Posted on 2023-10-12
2884 Glucose stress causes mRNA retention in nuclear Nab2 condensates
Heinrich, S.; Hondele, M.; Marchand, D.; Derrer, C. P.; Zedan, M.; Oswald, A.; Malinovska, L.; Uliana, F.; Khawaja, S.; Mancini, R.; Grunwald, D.; Weis, K.
10.1101/2022.01.30.478372 — cell biology — Posted on 2023-10-12
2885 Epigenetic and transcriptional plasticity drive inflammation in Cystic Fibrosis
Dinan, A. M.; Eneje, O.; Brown, K. P.; Burden, F.; Morse, M.; Prinjha, R.; Frontini, M.; Floto, R. A.
10.1101/2022.10.12.511886 — immunology — Posted on 2023-10-12
2890 GABRD promotes the progression of breast cancer through CDK1-dependent cell cycle regulation
Shang, Q.; Ren, F.; Feng, K.; Yang, C.; Zhao, S.; Liu, J.; Kang, X.; Yue, J.; Zhang, R.; Meng, X.; Wang, X.; Wang, X.
10.1101/2023.10.10.561812 — cancer biology — Posted on 2023-10-12
2891 Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells
Deen, A. J.; Adinolfi, S.; Harkonen, J.; Patinen, T.; Liu, X.; Laitinen, T.; Takabe, P.; Kainulainen, K.; Pasonen-Seppanen, S.; Gawriyski, L.; Thanigai Arasu, U.; Selvarajan, I.; Makinen, P.; Laitinen, H.; Kansanen, E.; Kaikkonen, M. U.; Poso, A.; Varjosalo, M.; Levonen, A.-L.
10.1101/2023.10.10.561664 — cancer biology — Posted on 2023-10-12
2892 Multiple lineages of transmissible neoplasia in the basket cockle (Clinocardium nuttallii) with repeated horizontal transfer of mitochondrial DNA
Yonemitsu, M. A.; Sevigny, J. K.; Vandepas, L. E.; Dimond, J. L.; Giersch, R. M.; Gurney-Smith, H. J.; Abbott, C. L.; Supernault, J.; Withler, R.; Smith, P. D.; Weinandt, S. A.; Garrett, F. E.; Sigo, R. L.; Unsell, E.; Crim, R. N.; Metzger, M. J.
10.1101/2023.10.11.561945 — cancer biology — Posted on 2023-10-12
2893 Histone H3 E50K mutation confers oncogenic activity and supports an EMT phenotype
Sad, K.; Jones, C. Y.; Lustenberger, S.; Lee, R. S.; Elayavalli, S. R.; Farhi, J.; Lemon, L. D.; Fasken, M. B.; Corbett, A. H.; Spangle, J. M.
10.1101/2023.10.11.561775 — cancer biology — Posted on 2023-10-12
2894 State-transition Modeling of Blood Transcriptome Predicts Disease Evolution and Treatment Response in Chronic Myeloid Leukemia (CML)
Frankhouser, D. E.; Rockne, R. C.; Uechi, L.; Zhao, D.; Branciamore, S.; O'Meally, D.; Izarriy, J.; Ghoda, L.; Ali, H.; Trent, J.; Forman, S.; Fu, Y.-H.; Kuo, Y.-H.; Zhang, B.; Marcucci, G.
10.1101/2023.10.11.561908 — cancer biology — Posted on 2023-10-12
2895 Tumor-targeted delivery of Tetanus toxoid by Listeria improves immunotherapy against ovarian cancer in mice
Scanlon, L. R.; Gabor, L.; Khouri, O. R.; Ahmad, S.; Levy, E.; Kuo, D. Y.-S.; Lin, K.; Nevadunsky, N.; Gravekamp, C.
10.1101/2023.10.11.561944 — cancer biology — Posted on 2023-10-12
2896 REL deregulation stands as a primary hit for AID-imprinted B-cells along the germinal center competition
Prevaud, L.; Vincent-Fabert, C.; Marchiol, T.; Lemasson, Q.; Ouk, C.; Carrion, C.; Cogne, M.; Feuillard, J.; Faumont, N.
10.1101/2023.10.10.561773 — cancer biology — Posted on 2023-10-12
2897 Single Cell Expression Analysis of Ductal Carcinoma in Situ Identifies Alterations in Epithelial Integrity
Qin, X.; Strand, S. H.; Lee, M. R.; van Ijzendoorn, D. G. P.; Zhu, C.; Vennam, S.; Varma, S.; Hall, A.; King, L.; Simpson, L.; Luo, X.; Colditz, G. A.; Jiang, S.; Hwang, E. S.; Marks, J. R.; Owzar, K.; West, R. B.
10.1101/2023.10.10.561724 — cancer biology — Posted on 2023-10-12
2901 Long-distance tmFRET using bipyridyl- and phenanthroline-based ligands
Gordon, S. E.; Evans, E. G.; Otto, S. C.; Tessmer, M.; Shaffer, K. D.; Gordon, M. T.; Petersson, J.; Stoll, S.; Zagotta, W. N.
10.1101/2023.10.09.561591 — biophysics — Posted on 2023-10-12
2902 Bayesian network models identify co-operative GPCR:G protein interactions that contribute to G protein coupling
Mukhaleva, E.; Ma, N.; Van Der Velden, W. J. C.; Gogoshin, G.; Branciamore, S.; Bhattacharya, S.; RODIN, A. S.; Vaidehi, N.
10.1101/2023.10.09.561618 — biophysics — Posted on 2023-10-12
2903 A novel subgroup of light-driven sodium pumps with an additional Schiff base counterion
Podoliak, E.; Lamm, G. H. U.; Alekseev, A.; Marin, E.; Schellbach, A. V.; Fedotov, D. A.; Stetsenko, A.; Maliar, N.; Bourenkov, G.; Balandin, T.; Baeken, C.; Astashkin, R.; Schneider, T. R.; Bateman, A.; Wachtveitl, J.; Schapiro, I.; Busskamp, V.; Guskov, A.; Gordeliy, V.; Kovalev, K.
10.1101/2023.10.11.561842 — biophysics — Posted on 2023-10-12
2907 Structural basis for CFTR inhibition by CFTRinh-172
Young, P.; Levring, J.; Fiedorczuk, K.; Blanchard, S. C.; Chen, J.
10.1101/2023.10.11.561899 — biophysics — Posted on 2023-10-12
2909 BASIS: BioAnalysis SEDFIT Integrated Software for cGMP Analysis of SV-AUC Data
Yarawsky, A. E.; Gough, E. S.; Zai-Rose, V.; Figueroa, N.; Cunningham, H. M.; Burgner, J. W.; Delion, M. T.; Paul, L. N.
10.1101/2023.10.12.562024 — biophysics — Posted on 2023-10-12
2912 Ultrahigh throughput evolution of tryptophan synthase in droplets via an aptamer-biosensor
Scheele, R.; Weber, Y.; Nintzel, F.; Herger, M.; Kaminski, T. S.; Hollfelder, F.
10.1101/2023.10.11.561886 — biochemistry — Posted on 2023-10-12
2914 A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis
Gopee, N. H.; Huang, N.; Olabi, B.; Admane, C.; Botting, R. A.; Foster, A. R.; Torabi, F.; Winheim, E.; Sumanaweera, D. N.; Goh, I.; Miah, M.; Stephenson, E.; Tun, W. M.; Moghimi, P.; Rumney, B.; He, P.; Lawrence, S.; Roberts, K.; Sidhpura, K.; Englebert, J.; Jardine, L.; Reynolds, G.; Rose, A.; Ganier, C.; Rowe, V.; Pritchard, S.; Mulas, I.; Fletcher, J.; Popescu, D.-M.; Poyner, E. F.; Dubois, A.; Filby, A.; Lisgo, S.; Barker, R. A.; PARK, J.-E.; Vento-Tormo, R.; Le, P. A.; Serdy, S.; Kim, J.; Deakin, C.; Lee, J.; Nikolova, M. T.; Rajan, N.; Ballereau, S.; Li, T.; Moore, J.; Horsfall, D.; Bas
10.1101/2023.10.12.556307 — developmental biology — Posted on 2023-10-12
2915 Tunneling nanotubes enable intercellular transfer in zebrafish embryos
Korenkova, O.; Liu, S.; Prlesi, I.; Pepe, A.; Albadri, S.; Del Bene, F.; Zurzolo, C.
10.1101/2023.10.12.562005 — cell biology — Posted on 2023-10-12
2916 Pseudo-linear Summation explains Neural Geometry of Multi-finger Movements in Human Premotor Cortex
Shah, N. P.; Avansino, D.; Kamdar, F.; Nicolas, C.; Kapitonava, A.; Vargas-Irwin, C.; Hochberg, L. R.; Pandarinath, C.; Shenoy, K.; Willett, F. R.; Henderson, J.
10.1101/2023.10.11.561982 — neuroscience — Posted on 2023-10-12
2925 Actin-Driven Nanotopography Promotes Stable Integrin Adhesion Formation in Developing Tissue
Chen, T.; Huertas Fernandez-Espartero, C.; Illand, A.; Tsai, C.-T.; Yang, Y.; Klapholz, B.; Jouchet, P.; Fabre, M.; Rossier, O.; Cui, B.; Leveque-Fort, S.; Brown, N. H.; Giannone, G.
10.1101/2023.07.28.550203 — cell biology — Posted on 2023-10-12
2926 ALS-associated FUS mutation reshapes the RNA and protein composition and dynamic of Stress Granules.
Mariani, D.; Setti, A.; Castagnetti, F.; Vitiello, E.; Mecarelli, L. S.; Di Timoteo, G.; Giuliani, A.; Perego, E.; Zappone, S.; Vicidomini, G.; Liessi, N.; Armirotti, A.; Bozzoni, I.
10.1101/2023.09.11.557245 — molecular biology — Posted on 2023-10-12
2927 In vitro reconstitution reveals membrane clustering and double-stranded RNA recruitment by the enteroviral AAA+ ATPase 2C
Shankar, K.; Sorin, M. N.; Skoglund, O.; Dahmane, S.; Sharma, H.; ter Beek, J.; Nenzen, L.; Carlson, L.-A.
10.1101/2023.10.11.561830 — microbiology — Posted on 2023-10-12
2931 Reactivation strength during cued recall is modulated by graph distance within cognitive maps
Kern, S.; Nagel, J.; Gerchen, M. F.; Gürsoy, C.; Meyer-Lindenberg, A.; Kirsch, P.; Dolan, R. J.; Gais, S.; Feld, G. B.
10.1101/2023.07.31.551234 — neuroscience — Posted on 2023-10-12
2934 Plasma of COVID-19 patients does not alter electrical resistance of human endothelial blood-brain barrier in vitro.
Pociute, A.; Kriauciunaite, K.; Kausyle, A.; Zablockiene, B.; Alcauskas, T.; Jelinskaite, A.; Rudenaite, A.; Jancioriene, L.; Rocka, S.; Verkhratsky, A.; Pivoriunas, A.
10.1101/2023.09.28.559927 — neuroscience — Posted on 2023-10-12
2936 Computational design of soluble analogues of integral membrane protein structures
Goverde, C. A.; Pacesa, M.; Dornfeld, L. J.; Goldbach, N.; Georgeon, S.; Rosset, S.; Dauparas, J.; Shellhaas, C.; Kozlov, S.; Baker, D.; Ovchinnikov, S.; Correia, B.
10.1101/2023.05.09.540044 — bioinformatics — Posted on 2023-10-12
2939 Evolutionary conserved multifunctional nitric oxide synthesis proteins responding to bacterial MAMPs are located at the endoplasmic reticulum
Zheng, W.; Li, H.; Fang, W.; Ipcho, S.; Hennessy, R. C.; Hansen, B. O.; Lu, G.; Wang, Z.; Newman, M.-A.; Olsson, S.
10.1101/2020.07.12.191361 — cell biology — Posted on 2023-10-12
2941 In vitro development and optimization of cell-laden injectable bioprinted gelatin methacryloyl (GelMA) microgels mineralized on the nanoscale
Sousa, M. G. C.; Balbinot, G. d. S.; Subbiah, R.; Visalakshan, R.; Tahayeri, A.; Verde, M. E. Q. L.; Athirasala, A.; Romanowicz, G.; Guldberg, R. E.; Bertassoni, L. E.
10.1101/2023.10.10.560919 — bioengineering — Posted on 2023-10-12
2944 An interactive cellular ecosystem blocks epithelial transformation in naked mole-rat
Behm, M.; Baeza-Centurion, P.; Penso-Dolfin, L.; Botey, F. J.; Hirschmuller, N.; Delaunay, S.; Koch, M.-L.; Del Prete, S.; Sohn, D.; Reifenberg, C.; Schopp, M.; Lammers, F.; Sole Boldo, L.; Dutton, J.; Begall, S.; Khaled, W.; Smith, E. S. J.; Odom, D. T.; Frye, M.; Goncalves, A.
10.1101/2023.10.10.561212 — cancer biology — Posted on 2023-10-12
2948 Biocomposite Thermoplastic Polyurethanes Containing Evolved Bacterial Spores as Living Fillers to Facilitate Polymer Disintegration
Kim, H. S.; Noh, M. H.; White, E. M.; Kandefer, M. V.; Wright, A. F.; Datta, D.; Lim, H. G.; Smiggs, E.; Locklin, J. J.; Rahman, M. A.; Feist, A. M.; Pokorski, J. K.
10.1101/2023.10.10.561602 — bioengineering — Posted on 2023-10-12
2952 Efficient Prohibitin 2 exposure during mitophagy depends on Voltage-dependent anion-selective channel protein 1.
Roy, M.; Nandy, S.; Marchesan, E.; Banerjee, C.; Mondal, R.; Caicci, F.; Ziviani, E.; CHAKRABORTY, J.
10.1101/2023.10.10.561633 — cell biology — Posted on 2023-10-12
2953 Role of RANKL in Alveolar Epithelial Cell Regeneration: Potential Novel Contributor to Lung Tissue Repair
Habibie, H.; Song, S.; Boorsma, C. E.; Putri, K. S. S.; Reker-Smit, C.; Vlasma, J.; Ruigrok, M. J. R.; Cool, R. H.; Wu, X.; Wang, Y.; Quax, W.; Olinga, P.; Brandsma, C.-A.; Timens, W.; Burgess, J.; Melgert, B. N.
10.1101/2023.10.11.561640 — cell biology — Posted on 2023-10-12
2955 Proteomic Analysis Reveals a PLK1-Dependent G2/M Degradation Program and Links PKA-AKAP2 to Cell Cycle Control
Mouery, R. D.; Hsu, C.; Bonacci, T.; Bolhuis, D. L.; Wang, X.; Mills, C. A.; Toomer, E. D.; Canterbury, O. G.; Robertson, K. C.; Branigan, T. B.; Brown, N. G.; Herring, L. E.; Emanuele, M.
10.1101/2023.10.11.561963 — cell biology — Posted on 2023-10-12
2956 Brefeldin A and M-COPA block the export of RTKs from the endoplasmic reticulum via simultaneous inactivation of ARF1, ARF4, and ARF5
Natsume, M.; Niwa, M.; Ichikawa, S.; Okamoto, T.; Tsutsui, H.; Usukura, D.; Murata, T.; Abe, R.; Shimonaka, M.; Nishida, T.; Shiina, I.; Obata, Y.
10.1101/2023.10.11.558504 — cell biology — Posted on 2023-10-12
2958 Utilising an in silico model to predict outcomes in senescence-driven acute liver injury
Ashmore-Harris, C.; Antonopoulou, E.; Aird, R. E.; Man, T. Y.; Finney, S. M.; Speel, A.; Lu, W.-Y.; Forbes, S. J.; Gadd, V. L.; Waters, S. L.
10.1101/2023.10.11.561528 — cell biology — Posted on 2023-10-12
2961 Systematic characterisation of perturbations in complex developing cell populations reveals mechanisms underpinning development and disease
Strauss, M. E.; Ton, M.-L. N.; Mason, S.; Bagri, J.; Harland, L. T.; Imaz-Rosshandler, I.; Wilson, N.; Gottgens, B.; Marioni, J. C.; Guibentif, C.
10.1101/2023.10.11.561904 — genomics — Posted on 2023-10-11
2965 Oligodendroglial precursors orchestrate immune network instigating early demyelination in experimental autoimmune encephalomyelitis
Wang, Q.; Huang, T.; Zheng, Z.; Su, Y.; Wu, Z.; Yu, G.; Liu, Y.; Wang, X.; Li, H.; Chen, X.; Jiang, Z.; Zhang, J.; Zhuang, Y.; Tian, Y.; Yang, Q.; Verkhratsky, A.; Wan, Y.; Yi, C.; Niu, J.
10.1101/2023.10.10.561804 — neuroscience — Posted on 2023-10-11
2967 Inferring ecological selection from multidimensional community trait distributions along environmental gradients
Kaarlejärvi, E.; Itter, M. S.; Tonteri, T.; Hamberg, L.; Salemaa, M.; Merilä, P.; Vanhatalo, J.; Laine, A.-L.
10.1101/2023.10.10.561738 — ecology — Posted on 2023-10-11
2970 CDH1 loss defines distinct diffuse-gastric cancer subtype with T cell exhaustion and EZH2 regulon activation
Zou, G.; Huang, Y.; Zhang, S.; Ko, K.-P.; Kim, B. J.; Zhang, J.; Venkatesan, V.; Pizzi, M. P.; Jun, S.; Niu, N.; Wang, H.; Song, S.; Ajani, J. A.; Park, J.-I.
10.1101/2023.03.23.533976 — cancer biology — Posted on 2023-10-11
2973 Vertical transmission of maternal DNA through extracellular vesicles associates with altered embryo bioenergetics during the periconception period
Bolumar, D.; Moncayo-Arlandi, J.; Gonzalez-Fernandez, J.; Ochando, A.; Moreno, I.; Monteagudo-Sanchez, A.; Marin, C.; Diez, A.; Fabra, P.; Checa, M. A.; Espinos, J. J.; Gardner, D. K.; Simon, C.; Vilella, F.
10.1101/2023.04.21.537765 — developmental biology — Posted on 2023-10-11
2974 PCLAF-DREAM Drives Alveolar Cell Plasticity for Lung Regeneration
Kim, B.; Huang, Y.; Ko, K.-P.; Zhang, S.; Zou, G.; Zhang, J.; Kim, M.; Little, D.; Ellis, L. V.; Paschini, M.; Jun, S.; Park, K.-S.; Chen, J.; Kim, C.; Park, J.-I.
10.1101/2022.10.11.511761 — cell biology — Posted on 2023-10-11
2975 A deep neural network estimation of brain age is sensitive to cognitive impairment and decline
Yang, Y.; Sathe, A.; Schilling, K.; Shashikumar, N.; Moore, E.; Dumitrescu, L.; Pechman, K. R.; Landman, B. A.; Gifford, K. A.; Hohman, T. J.; Jefferson, A. L.; Archer, D. B.
10.1101/2023.08.10.552494 — neuroscience — Posted on 2023-10-11
2976 Time Tiling of Learned Stimulus-Based Decision Making in Dorsal CA1 in the Hippocampus
Ma, M.; Simoes de Souza, F.; Futia, G. L.; Anderson, S. R.; Riguero, J.; Tollin, D.; Gentile-Polese, A.; Platt, J. P.; Hiratani, N.; Gibson, E. A.; Restrepo, D.
10.1101/2023.10.01.560382 — neuroscience — Posted on 2023-10-11
2981 Machine learning determines stemness associated with simple and basal-like canine mammary carcinomas
Xavier, P. L. P.; Marcao, M.; Simoes, R. L.; Job, M. E. G.; Strefezzi, R. d. F.; Fukumasu, H.; Malta, T. M.
10.1101/2023.10.09.561566 — cancer biology — Posted on 2023-10-11
2982 New realm of precision multiplexing enabled by massively-parallel single molecule UltraPCR
Lai, J. H.; Keum, J. w.; Lee, H. G.; Molaei, M.; Blair, E. J.; Li, S.; Soliman, J. W.; Raol, V. K.; Barker, C. L.; Fodor, S. P.; Fan, H. C.; Shum, E. Y.
10.1101/2023.10.09.561546 — biophysics — Posted on 2023-10-11
2986 Insights into Plant Interactions and the Biogeochemical Role of the Globally Widespread Acidobacteriota Phylum
Goncalves, O. S.; Fernandes, A. S.; Tupy, S. M.; Ferreira, T. G.; Almeida, L. N.; Creevey, C. J.; Santana, M. F.
10.1101/2023.10.09.561551 — genomics — Posted on 2023-10-11
2987 Integrating large-scale meta-GWAS and PigGTEx resources to decipher the genetic basis of complex traits in pig.
Xu, Z.; Lin, Q.; Cai, X.; Zhong, Z.; Li, B.; Teng, J.; Zeng, H.; Gao, Y.; Cai, Z.; Wang, X.; Shi, L.; Wang, X.; Wang, Y.; Zhang, Z.; Lin, Y.; Liu, S.; Yin, H.; Bai, Z.; Wei, C.; Zhou, J.; Zhang, W.; Zhang, X.; Shi, S.; Wu, J.; Diao, S.; Liu, Y.; Pan, X.; Feng, X.; Liu, R.; Su, Z.; Chang, C.; Zhu, Q.; Wu, Y.; The PigGTEx Consortium, ; Zhou, Z.; Bai, L.; Li, K.; Wang, Q.; Pan, Y.; Xu, Z.; Peng, X.; Mei, S.; Mo, D.; Liu, X.; Zhang, H.; Yuan, X.; Liu, Y.; Liu, G. E.; Su, G.; Sahana, G.; Lund, M.; Ma, L.; Xiang, R.; Shen, X.; Li, P.; Huang, R.; Ballester, M.; Crespo-Piazuelo, D.; Amills, M.; Clop,
10.1101/2023.10.09.561393 — genetics — Posted on 2023-10-11
2991 ECM-Focused Proteomic Analysis of Ear Punch Regeneration in Acomys cahirinus
McCabe, M. C.; Okamura, D. M.; Erickson, C. B.; Perry, B. W.; Brewer, C. M.; Nguyen, E. D.; Saviola, A. J.; Majesky, M. W.; Hansen, K. C.
10.1101/2023.10.11.561940 — molecular biology — Posted on 2023-10-11
2992 Defining the mechanism of galectin-3-mediated TGF-β1 activation and its role in lung fibrosis.
Calver, J. F.; Parmar, N. R.; Harris, G.; Lithgo, R. M.; Stylianou, P.; Zetterberg, F. R.; Gooptu, B.; Mackinnon, A. C.; Slack, R. J.; Carr, S. B.; Scott, D. J.; Jenkins, R. G.; John, A. E.
10.1101/2023.10.11.561855 — molecular biology — Posted on 2023-10-11
2994 Open-source, high-throughput targeted in-situ transcriptomics for developmental biologists
Lee, H.; Mattsson Langseth, C.; Marco Salas, S.; Metousis, A.; Rueda Alana, E.; Garcia Moreno, F.; Grillo, M.; Nilsson, M.
10.1101/2023.10.10.561689 — molecular biology — Posted on 2023-10-11
2995 Molecular dependencies and genomic consequences of a global DNA damage tolerance defect
de Groot, D.; Spanjaard, A.; Shah, R.; Kreft, M.; Morris, B.; Lieftink, C.; Catsman, J. J. I.; Ormel, S.; Ayidah, M.; Pilzecker, B.; Buoninfante, O. A.; van denBerk, P. C. M.; Beijersbergen, R. L.; Jacobs, H.
10.1101/2023.10.11.561854 — molecular biology — Posted on 2023-10-11
2996 A methoxylated flavone from Artemisia afra kills Mycobacterium tuberculosis
Kellogg, J. J.; Alonso, M. N.; Jordan, R. T.; Xiao, J.; Cafiero, J. H.; Bush, T.; Towler, M. J.; Weathers, P.; Shell, S.
10.1101/2023.10.11.561885 — microbiology — Posted on 2023-10-11
2997 Nitrogen sources enhance siderophore-mediated competition for iron between potato common scab and late blight causative agents
Stulanovic, N.; Kerdel, Y.; Rezende, L.; Deflandre, B.; Burguet, P.; Belde, L.; Denoel, R.; Tellatin, D.; Rigolet, A.; Hanikenne, M.; Quinton, L.; Ongena, M.; Rigali, S.
10.1101/2023.10.11.561833 — microbiology — Posted on 2023-10-11
2998 Importin-7-dependent nuclear localization of the Flavivirus core protein is required for infectious virus production.
Itoh, Y.; Tokunaga, M.; Miyamoto, Y.; Suzuki, T.; Takada, A.; Ninomiya, A.; Matsuda, M.; Yoneda, Y.; Oka, M.; Suzuki, R.; Matsuura, Y.; Okamoto, T.
10.1101/2023.10.11.561943 — microbiology — Posted on 2023-10-11
2999 Aminoglycoside heteroresistance in Enterobacter cloacae is driven by the cell envelope stress response.
Choi, A. J.; Bennison, D. J.; Kulkarni, E.; Sun, H.; Li, H.; Bradshaw, J.; Yeap, H. W.; Mishra, V.; Crespo-Puig, A.; Davies, F.; Sriskandan, S.; Shenoy, A. R.
10.1101/2023.10.11.561937 — microbiology — Posted on 2023-10-11
3001 Seminal plasma inhibits Chlamydia trachomatis infection in vitro, and may have consequences on mucosal immunity
Reot, L.; Adapen, C.; Cannou, C.; Nunez, N.; Lakoum, S.; Pimienta, C.; Lacroix, L.; Binois, O.; Frydman, N.; Nugeyre, M.-T.; Le Grand, R.; Menu, E.
10.1101/2023.10.10.561648 — immunology — Posted on 2023-10-11
3002 Reduced S-acylation of SQSTM1/p62 in Huntington disease is associated with impaired autophagy
Abrar, F.; Davies, M. C.; Kumar, A.; Dang, A.; Nguyen, Y. T. N.; Collins, J.; Caron, N. S.; Choudhary, J. S.; Sanders, S. S.; Collins, M. O.; Hayden, M. R.; Martin, D. D. O.
10.1101/2023.10.11.561600 — neuroscience — Posted on 2023-10-11
3003 OxPhos in adipose tissue macrophages regulated by BTK enhances their M2-like phenotype and confers a systemic immunometabolic benefit in obesity
Purvis, G.; Collino, M.; Van Dam, A.; Einaudi, G.; Ng, Y.; Shanmuganathan, M.; Patel, S.; Thiemermann, C.; Channon, K.; Greaves, D.
10.1101/2023.10.09.561199 — pathology — Posted on 2023-10-11
3005 TMEM65-dependent Ca2+ extrusion safeguards mitochondrial homeostasis
Vetralla, M.; Wischhof, L.; Cadenelli, V.; Scifo, E.; Ehninger, D.; Rizzuto, R.; Bano, D.; De Stefani, D.
10.1101/2023.10.10.561661 — biochemistry — Posted on 2023-10-11
3006 p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response
Serra, F.; Nieto-Aliseda, A.; Fanlo, L.; Rovirosa, L.; Cabrera-Pasadas, M.; Lazarenkov, A.; Urmeneta, B.; Alcalde, A.; Nola, E. M.; Okorokov, A. L.; Fraser, P.; Graupera, M.; Castillo, S. D.; Sardina, J. L.; Valencia, A.; Javierre, B. M.
10.1101/2023.10.10.561663 — genomics — Posted on 2023-10-11
3008 DNA methylation is linked to the monoallelic expression of MRP3, a diatom mating type determining gene
Ruggiero, A.; Mager, S.; Manfellotto, F.; Di Tuccio, V.; NISHIMURA, T.; Russo, M. T.; Sanges, R.; Ferrante, M. I.; Pan, L.
10.1101/2023.10.11.561864 — genetics — Posted on 2023-10-11
3010 Snapshots from Cryo-ET of active SARS-CoV-2 virions
Fukuhara, H.; Dokainish, H. M.; Kita, S.; Tabata, K.; Takasu, A.; Huiskonen, J. T.; Anraku, Y.; Senda, T.; Stuart, D. I.; Sasaki, M.; Orba, Y.; Suzuki, Y.; Sawa, H.; Maenaka, K.
10.1101/2023.10.10.561643 — microbiology — Posted on 2023-10-11
3011 Integration of 168,000 samples reveals global patterns of the human gut microbiome
Abdill, R. J.; Graham, S. P.; Rubinetti, V.; Albert, F. W.; Greene, C. S.; Davis, S.; Blekhman, R.
10.1101/2023.10.11.560955 — microbiology — Posted on 2023-10-11
3012 In vitro reconstitution reveals membrane clustering and double-stranded RNA recruitment by the enteroviral AAA+ ATPase 2C
Shankar, K.; Sorin, M. N.; Skoglund, O.; Dahmane, S.; Sharma, H.; ter Beek, J.; Nenzen, L.; Carlson, L.-A.
10.1101/2023.10.11.561830 — microbiology — Posted on 2023-10-11
3013 Developmental isoform diversity in the human neocortex informs neuropsychiatric risk mechanisms
Patowary, A.; Zhang, P.; Jops, C.; Vuong, C.; Ge, X.; Hou, K.; Kim, M.; Gong, N.; Margolis, M.; Vo, D.; Wang, X.; Liu, C.; Pasaniuc, B.; Li, J. J.; Gandal, M.; de la Torre-Ubieta, L.
10.1101/2023.03.25.534016 — genomics — Posted on 2023-10-11
3017 GLYCOLYTIC REPROGRAMMING FUELS MYELOID CELL-DRIVEN HYPERCOAGULABILITY
Rehill, A. M.; Leon, G.; McCluskey, S.; Schoen, I.; Hernandez-Santana, Y.; Annett, S. L.; Klavina, P.; Robson, T.; Curtis, A. M.; Renne, T.; Hussey, S.; O'Donnell, J. S.; Walsh, P. T.; Preston, R. J.
10.1101/2023.04.20.537683 — immunology — Posted on 2023-10-11
3020 Fecal metagenomics to identify biomarkers of food intake in healthy adults: Findings from randomized, controlled, nutrition trials
Shinn, L. M.; Mansharamani, A.; Baer, D. J.; Novotny, J. A.; Charron, C. S.; Khan, N. A.; Zhu, R.; Holscher, H. D.
10.1101/2023.04.10.536271 — bioinformatics — Posted on 2023-10-11
3021 The landscape of cancer rewired GPCR signaling axes
Arora, C.; Matic, M.; DiChiaro, P.; Rosa, N. D. O.; Carli, F.; Nemati, L.; Clubb, L.; Kargas, G.; Diaferia, G.; Vukotic, R.; Licata, L.; Wu, G.; Natoli, G.; Gutkind, J. S.; Raimondi, F.
10.1101/2023.03.13.532291 — bioinformatics — Posted on 2023-10-11
3023 Multiple genetic variants at the SLC30A8 locus affect local super-enhancer activity and influence pancreatic β cell survival and function
Hu, M.; Kim, I.; Moran, I.; Peng, W.; Sun, O.; Bonnefond, A.; Khamnis, A.; Bonas-Guarch, S.; Froguel, P.; Rutter, G. A.
10.1101/2023.07.13.548906 — cell biology — Posted on 2023-10-11
3024 Temperature elevation synergises with and enhances the type-I IFN-mediated restriction of MPXV
Davis, C.; Epifano, I.; Dee, K.; McFarlane, S.; Wojtus, J. K.; Brennan, B.; Gu, Q.; Vattipally, S. B.; Tong, L.; Orr, L.; Filipe, A. D. S.; Barr, D. A.; Ho, A.; Thomson, E. C.; Boutell, C.
10.1101/2023.09.29.560106 — microbiology — Posted on 2023-10-11
3025 Cholecystokinin gates reproduction in zebrafish by controlling gonadotropin secretion
Hollander cohen, L.; Cohen, O.; Shulman, M.; Aiznkot, T.; Fontanaud, P.; Revah, O.; Mollard, P.; Golan, M.; Levavi Sivan, B.
10.1101/2023.06.18.545454 — neuroscience — Posted on 2023-10-11
3029 Cation permeability and pore dynamics in TRPV1 ion channels
Garcia-Avila, M.; Tello Marmolejo, J.; Rosenbaum, T.; Islas, L. D.
10.1101/2023.05.25.542342 — biophysics — Posted on 2023-10-11
3030 Insights into deuterostome evolution from the biphasic transcriptional programmes of hemichordates
Perez-Posada, A.; Lin, C.-Y.; Fan, T.-P.; Lin, C.-Y.; Chen, Y.-C.; Gomez-Skarmeta, J. L.; Yu, J.-K.; Su, Y.-H.; Tena, J. J.
10.1101/2022.06.10.495707 — evolutionary biology — Posted on 2023-10-11
3032 A new mechanism of posttranslational polyglutamylation regulates phase separation and signaling of the Wnt pathway protein Dishevelled.
Kravec, M.; Sedo, O.; Nedvedova, J.; Micka, M.; Sulcova, M.; Zezula, N.; Gomoryova, K.; Potesil, D.; Ganji, R. S.; Cervenka, I.; Zdrahal, Z.; Harnos, J.; Tripsianes, K.; Janke, C.; Barinka, C.; Bryja, V.
10.1101/2023.07.28.550915 — cell biology — Posted on 2023-10-11
3034 β-carotene accelerates the resolution of atherosclerosis in mice
Pinos, I.; Coronel, J.; Albakri, A.; Blanco, A.; McQueen, P.; Molina, D.; Sim, J.; Fisher, E. A.; Amengual, J.
10.1101/2023.03.07.531563 — immunology — Posted on 2023-10-11
3036 Cholinergic modulation of motor sequence learning
Voegtle, A.; Mohrbutter, C.; Hils, J.; Schulz, S.; Weuthen, A.; Bramer, U.; Ullsperger, M.; Sweeney-Reed, C. M.
10.1101/2023.10.11.561645 — neuroscience — Posted on 2023-10-11
3037 A frame and a hotspot in cochlear mechanics
Strimbu, C. E.; Chiriboga, L. A.; Frost, B. L.; Fallah, E.; Olson, E. S.
10.1101/2023.06.29.547111 — neuroscience — Posted on 2023-10-11
3040 Loss of TMEM65 causes mitochondrial disease mediated by mitochondrial calcium
Zhang, Y.; Reyes, L.; Sun, J.; Liu, C.; Springer, D.; Noguchi, A. C.; Aponte, A. M.; Munasinghe, J.; Covian, R.; Murphy, E.; Glancy, B.
10.1101/2022.08.02.502535 — physiology — Posted on 2023-10-11
3042 Non-coding variants impact cis-regulatory coordination in a cell type-specific manner
Pushkarev, O.; van Mierlo, G.; Kribelbauer, J. F.; Saelens, W.; Gardeux, V.; Deplancke, B.
10.1101/2023.10.11.561870 — genomics — Posted on 2023-10-11
3043 Alternative splicing is coupled to gene expression in a subset of variably expressed genes
Karlebach, G.; Steinhaus, R.; Danis, D.; Devoucoux, M.; Anczukow, O.; Sheynkman, G.; Seelow, D.; Robinson, P. N.
10.1101/2023.06.13.544742 — genomics — Posted on 2023-10-11
3046 Scale-independent topological interactions drive the first fate decision in the Drosophila embryo
Hur, W.; Mukherjee, A.; Hayden, L.; Lu, Z.; Chao, A.; Mitchell, N. P.; Streichan, S. J.; Vergassola, M.; Di Talia, S.
10.1101/2023.10.11.561879 — developmental biology — Posted on 2023-10-11
3048 Cross-modal sensory compensation increases mosquito attraction to humans
Morita, T.; Lyn, N. G.; von Heynitz, R. K.; Goldman, O. V.; Sorrells, T. R.; DeGennaro, M.; Matthews, B. J.; Houri-Zeevi, L.; Vosshall, L. B.
10.1101/2023.10.10.561721 — neuroscience — Posted on 2023-10-11
3050 ASCT2 is the primary serine transporter in cancer cells
Conger, K. O.; Chidley, C.; Ozgurses, M. E.; Zhao, H.; Kim, Y.; Semina, S. E.; Burns, P. A.; Rawat, V.; Sheldon, R.; Ben-Sahra, I.; Frasor, J.; Sorger, P. K.; DeNicola, G. M.; Coloff, J. L.
10.1101/2023.10.09.561530 — cancer biology — Posted on 2023-10-11
3051 Measuring conformational equilibria in allosteric proteins with time-resolved tmFRET
Zagotta, W. N.; Evans, E. G.; Eggan, P.; Tessmer, M.; Shaffer, K. D.; Petersson, J.; Stoll, S.; Gordon, S. E.
10.1101/2023.10.09.561594 — biophysics — Posted on 2023-10-11
3052 Systemic Metabolic Depletion of Intestine Microbiome Undermines Melanoma Immunotherapy Effectiveness
Zakharevich, N. V.; Morozov, M. D.; Kanaeva, V. A.; Ivanov, A. B.; Ulyantsev, V. I.; Klimina, K. M.; Olekhnovich, E. I.
10.1101/2023.10.09.561540 — bioinformatics — Posted on 2023-10-11
3053 Site-specific arrangement and structure determination of minor groove binding molecules in self-assembled three-dimensional DNA crystals
Simmons, C. R.; Buchberger, A.; Henry, S. J. W.; Novacek, A.; Fahmi, N. E.; MacCulloch, T.; Stephanopoulos, N.; Yan, H.
10.1101/2023.10.10.561756 — bioengineering — Posted on 2023-10-11
3056 Mechanical Properties of Native and Decellularized Reproductive Tissues: Insights for Tissue Engineering Strategies
Franko, R.; Franko, Y.; Martinez, E. R.; Ferronato, G.; Heinzelmann, I.; Grechi, N.; Devkota, S.; Fontes, P. K.; Coeti, R.; Oshiro, T. S. I.; Ferraz, M. d. A. M. M.
10.1101/2023.10.09.561536 — bioengineering — Posted on 2023-10-11
3057 Transcriptome analysis in a humanized mouse model of familial dysautonomia reveals tissue-specific gene expression disruption in the peripheral nervous system.
Harripaul, R. S.; Morini, E.; Salani, M.; Logan, E.; Kirchner, E. G.; Bolduc, J.; Chekuri, A.; Currall, B.; Yadav, R.; Erdin, S.; Talkowski, M. E.; GAO, D.; Slaugenhaupt, S.
10.1101/2023.09.28.559870 — genomics — Posted on 2023-10-11
3058 The single-molecule accessibility landscape of newly replicated mammalian chromatin
Ostrowski, M. S.; Yang, M. G.; McNally, C. P.; Abdulhay, N. J.; Wang, S.; Nora, E. P.; Goodarzi, H.; Ramani, V.
10.1101/2023.10.09.561582 — genomics — Posted on 2023-10-11
3059 An osmolarity dependent mechanism partially ameliorates retinal cysts and rescues cone function in a mouse model of X-linked Retinoschisis.
Gehrke, E. J.; Thompson, J.; Kalmanek, E.; Stanley, S. T.; Bhattarai, S.; Lobeck, B.; Mayer, S. K.; Mahoney, A.; Hassan, S.; Hsu, Y.; Drack, A.
10.1101/2023.10.09.561513 — genetics — Posted on 2023-10-11
3060 Hemangiosarcoma Cells Promote Conserved Host-Derived Hematopoietic Expansion
Kim, J. H.; Schulte, A. J.; Sarver, A. L.; Angelos, M. G.; Frantz, A. M.; Foster, C. L.; O'Brien, T. D.; Cornax, I.; O'Sullivan, M. G.; Cheng, N.; Lewellen, M.; Oseth, L.; Kumar, S.; Bullman, S.; Pedamallu, C. S.; Goyal, S. M.; Meyerson, M.; Lund, T. C.; Alfoldi, J.; Breen, M.; Lindblad-Toh, K.; Dickerson, E. B.; Kaufman, D. S.; Modiano, J. F.
10.1101/2021.05.21.445198 — cancer biology — Posted on 2023-10-11
3061 HIPSD&R-seq enables scalable genomic copy number and transcriptome profiling
Lazareva, O.; Malm, J. P.; Simovic-Lorenz, M.; Philippos, G.; Sant, P.; Parekh, U.; Hammann, L.; Li, A.; Yildiz, U.; Marttinen, M.; Zaugg, J. B.; Noh, K. M.; Stegle, O.; Ernst, A.
10.1101/2023.10.09.561487 — cancer biology — Posted on 2023-10-11
3062 A method for rapid nanobody screening with no bias of the library diversity
He, L.; Tao, Z.; Zhao, X.; Wang, H.; Zhang, J.; Jiang, G.; Yu, B.; Chen, Y.; Zhu, M.; Long, J.; Yin, L.; Zhang, X.; Liu, M.
10.1101/2023.02.15.528753 — biochemistry — Posted on 2023-10-11
3065 Time-, tissue- and treatment-associated heterogeneity in tumour-residing migratory DCs
Lee, C. Y.; Kennedy, B. C.; Richoz, N.; Dean, I.; Tuong, Z. K.; Gaspal, F.; Li, Z.; Willis, C.; Hasegawa, T.; Whiteside, S. K.; Posner, D. A.; Carlesso, G.; Hammond, S. A.; Dovedi, S.; Roychoudhuri, R.; Withers, D. R.; Clatworthy, M. R.
10.1101/2023.07.03.547454 — immunology — Posted on 2023-10-11
3066 Commensal Bacteria Maintain a Qa-1b-restricted Unconventional CD8+ T Population in Gut Epithelium
Guan, J.; Peske, J. D.; Manoharan Valerio, M.; Park, C.; Robey, E. A.; Sadegh-Nasseri, S.
10.1101/2023.03.01.530600 — immunology — Posted on 2023-10-11
3067 Activation of the P2RX7/IL-18 pathway in immune cells attenuates lung fibrosis
Janho dit Hreich, S.; Juhel, T.; Leroy, S.; Brau, F.; Hofman, V.; Hofman, P.; Vouret-Craviari, V.
10.1101/2022.12.15.520590 — immunology — Posted on 2023-10-11
3068 Cell type-focused compound screen in human organoids reveals molecules and pathways controlling cone photoreceptor death
Spirig, S. E.; Arteaga-Moreta, V. J.; Raics, Z.; Posada-Cespedes, S.; Chreng, S.; Galuba, O.; Galuba, I.; Claerr, I.; Renner, S.; Kleindienst, T.; Volak, A.; Imbach, J.; Malysheva, S.; Siwicki, R. A.; Hahaut, V.; Hou, Y.; Picelli, S.; Cattaneo, M.; Jüttner, J.; Cowan, C. S.; Duckely, M.; Baeschlin, D. K.; Renner, M.; Unterreiner, V.; Roska, B.
10.1101/2023.10.09.561525 — neuroscience — Posted on 2023-10-11
3070 The genetic and dietary landscape of the muscle insulin signalling network
van Gerwen, J.; Masson, S. W. C.; Cutler, H. B.; Diaz-Vegas, A.; Potter, M.; Stockli, J.; Madsen, S.; Nelson, M. E.; Humphrey, S. J.; James, D. E.
10.1101/2023.06.21.546001 — systems biology — Posted on 2023-10-11
3073 Mitochondrial perturbation of the epithelium causes microbial dysbiosis and unresolved tissue injury in intestinal inflammation
Urbauer, E.; Aguanno, D.; Mindermann, N.; Omer, H.; Metwaly, A.; Khaloian, S.; Reitmeier, S.; Remke, M.; Jarosch, S.; Huber, S.; Busch, D. H.; Stecher, B.; Allez, M.; Steiger, K.; Rath, E.; Haller, D.
10.1101/2023.07.27.549844 — microbiology — Posted on 2023-10-11
3076 The benzoxazinoid breakdown product 5-Methoxy-2-Nitrophenol has a dual function in maize defense against herbivory
Schimmel, B. C. J.; Escobar-Bravo, R.; Mateo, P.; Chen, C.; Glauser, G.; Ogi, V.; Wang, L.; Verdecia-Mogena, A.; Robert, C. A. M.; Erb, M.
10.1101/2023.10.10.561717 — plant biology — Posted on 2023-10-11
3078 The Hidden Diversity of Vascular Patterns in Flower Heads
Owens, A.; Zhang, T.; Gu, P.; Hart, J.; Stobbs, J.; Cieslak, M.; Elomaa, P.; Prusinkiewicz, P.
10.1101/2023.10.10.561718 — plant biology — Posted on 2023-10-11
3080 Data-driven optimization yielded a highly-efficient CRISPR/Cas9 system for gene editing in Arabidopsis
Geng, H.; Wang, Y.; Xu, Y.; Zhang, Y.; Han, E.; Peng, Y.; Geng, Z.; Liu, Y.; Qin, Y.; Ma, S.
10.1101/2023.10.09.561629 — plant biology — Posted on 2023-10-11
3084 Cellular landscape of adrenocortical carcinoma at single-nuclei resolution
Tourigny, D. S.; Altieri, B.; Secener, K. A.; Sbiera, S.; Schauer, M. P.; Arampatzi, P.; Herterich, S.; Sauer, S. S.; Fassnacht, M.; Ronchi, C. L.
10.1101/2023.10.09.561514 — cancer biology — Posted on 2023-10-11
3087 Cell-type-specific characterization of miRNA gene dynamics in immune cell subpopulations during aging and atherosclerosis disease development at single-cell resolution
de Sande, A. H.; Turunen, T.; Bouvy-Liivrand, M.; Ord, T.; Palani, S.; Tundidor-Centeno, C.; Liljenback, H.; Virta, J.; Smolander, O.-P.; Sinkkonen, L.; Sauter, T.; Roivainen, A.; Lonnberg, T.; Kaikkonen, M. U.; Heinaniemi, M.
10.1101/2023.10.09.561173 — molecular biology — Posted on 2023-10-11
3088 Identification of Determinants that Allow Maintenance of High-Level Fluoroquinolone Resistance in Acinetobacter baumannii
Hamami, E.; Huo, W.; Castaneda, A.; Bai, J.; Syal, S.; Ortiz-Marquez, J. C.; van Opijnen, T.; Geisinger, E.; Isberg, R. R.
10.1101/2023.10.03.560562 — microbiology — Posted on 2023-10-11
3091 Circulating senescent myeloid cells drive blood brain barrier breakdown and neurodegeneration
Wilk, C. M.; Cathomas, F.; Torok, O.; Le Berichel, J.; Park, M. D.; Heaton, G. R.; Hamon, P.; Troncoso, L.; Scull, B. P.; Dangoor, D.; Silvin, A.; Fleischmann, R.; Belabed, M.; Lin, H.; Taouli, E. M.; Boettcher, S.; Manz, M. G.; Kofler, J. K.; Yue, Z.; Lira, S. A.; Ginhoux, F.; Crary, J. F.; McClain, K. L.; Picarsic, J. L.; Russo, S. J.; Allen, C. E.; Merad, M.
10.1101/2023.10.10.561744 — cell biology — Posted on 2023-10-11
3092 Mapping lung hematopoietic progenitors: Developmental kinetics and response to Influenza A viral infection
Mincham, K. T.; Lauzon-Joset, J.-F.; Read, J. F.; Holt, P. G.; Stumbles, P. A.; Strickland, D. H.
10.1101/2023.10.09.561586 — immunology — Posted on 2023-10-11
3096 A highly resolved multiplex network reveals the structural role of insects and plants in terrestrial food webs
Hale, K. R. S.; Curlis, J. D.; Auteri, G. G.; Bishop, S.; French, R. L. K.; Jones, L. E.; Mills, K. L.; Simons, M.; Scholtens, B. G.; Thompson, C.; Tourville, J.; Valdovinos, F. S.
10.1101/2023.10.05.560934 — ecology — Posted on 2023-10-11
3098 Phage-induced efflux down-regulation boosts antibiotic efficacy
Kraus, S.; Lapinska, U.; Chawla, K.; Baker, E.; Attrill, E.; ONeill, P.; Farbos, A.; Jeffries, A.; Galyov, E.; Korbsrisate, S.; Barnes, K.; Harding, S.; Tsaneva-Atanasova, K.; Blaskovich, M.; Pagliara, S.
10.1101/2023.09.21.558807 — microbiology — Posted on 2023-10-11
3102 Role of Dynamin-Related Proteins 2 and SH3P2 in Clathrin-Mediated Endocytosis in Plants
Gnyliukh, N.; Johnson, A.; Nagel, M.-K.; Monzer, A.; Hlavata, A.; Isono, E.; Loose, M.; Friml, J.
10.1101/2023.10.09.561523 — plant biology — Posted on 2023-10-10
3104 AlphaFold2 can predict single-mutation effects
Mcbride, J. M.; Reinharz, V.; Polev, K.; Grzybowski, B. A.; Tlusty, T.
10.1101/2022.04.14.488301 — biochemistry — Posted on 2023-10-10
3105 An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome
Liu, S.; Ezran, C.; Wang, M. F. Z.; Li, Z.; Awayan, K.; The Tabula Microcebus Consortium, ; Long, J. Z.; De Vlaminck, I.; Wang, S.; Epelbaum, J.; Kuo, C.; Terrien, J.; Krasnow, M. A.; Ferrell, J. E.
10.1101/2021.12.13.472243 — genomics — Posted on 2023-10-10
3106 The impact of common variants on gene expression in the human brain: from RNA to protein to schizophrenia risk
Liang, Q.; Jiang, Y.; Shieh, A. W.; Zhou, D.; Chen, R.; Wang, F.; Xu, M.; Niu, M.; Wang, X.; Pinto, D.; Wang, Y.; Cheng, L.; Vadukapuram, R.; Zhang, C.; Grennan, K.; Giase, G.; The PsychENCODE Consortium, ; White, K. P.; Peng, J.; Li, B.; Liu, C.; Chen, C.; Wang, S. H.
10.1101/2023.06.04.543603 — genetics — Posted on 2023-10-10
3110 Interplay of RAP2 GTPase and the cytoskeleton in Hippo pathway regulation
Wu, C.; Cai, X.; Wang, Y.; Rodriguez, C. D.; Herrmann, L.; Zoaldi, G.; Huang, C.-Y.; Wang, X.; Sanghvi, V. R.; Lu, R. O.; Meng, Z.
10.1101/2023.10.10.561687 — cell biology — Posted on 2023-10-10
3111 Control of intestinal stemness and cell lineage by histone variant H2A.Z isoforms
Rispal, J.; Rives, C.; Jouffret, V.; Leoni, C.; Dubois, L.; Chevillard-Briet, M.; Trouche, D.; Escaffit, F.
10.1101/2023.10.10.561706 — cell biology — Posted on 2023-10-10
3115 Aminergic and peptidergic modulation of Insulin-Producing Cells in Drosophila
Held, M.; Bisen, R. S.; Zandawala, M. M.; Chockley, A. S.; Balles, I. S.; Hilpert, S.; Liessem, S.; Cascino-Milani, F.; Ache, J. M.
10.1101/2023.09.14.557555 — neuroscience — Posted on 2023-10-10
3116 A conserved ESCRT-II-like protein participates in the biogenesis and maintenance of thylakoid membranes
Yilmazer, I.; Vetrano, P.; Eicke, S.; Abt, M. R.; Traverso, E.; Morosinotto, T.; Zeeman, S. C.; Ramundo, S.; Sharma, M.
10.1101/2023.10.10.561251 — plant biology — Posted on 2023-10-10
3118 Australian terrestrial environments harbour extensive RNA virus diversity
Sadiq, S.; Harvey, E.; Mifsud, J. C.; Minasny, B.; McBratney, A. B.; Pozza, L. E.; Mahar, J. E.; Holmes, E. C.
10.1101/2023.10.09.561620 — microbiology — Posted on 2023-10-10
3119 Acute and chronic alcohol modulation of extended amygdala calcium dynamics
Roland, A.; Chao, T.-H.; Hon, O.; Machinski, S.; Sides, T.; Lee, S.; Shih, Y.-Y. I.; Kash, T.
10.1101/2023.10.10.561741 — neuroscience — Posted on 2023-10-10
3120 Transient brain activity dynamics discriminate levels of consciousness during anesthesia
Ensel, S.; Uhrig, L.; Ozkirli, A.; Hoffner, G.; Tasserie, J.; Dehaene, S.; Van De Ville, D.; Jarraya, B.; Pirondini, E.
10.1101/2023.10.09.560209 — neuroscience — Posted on 2023-10-10
3121 Multidimensional Analysis of the Adult Human Heart in Health and Disease using Hierarchical Phase-Contrast Tomography (HiP-CT)
Brunet, J.; Cook, A. C.; Walsh, C. L.; Cranley, J.; Tafforeau, P.; Engel, K.; Berruyer, C.; Burke O'Leary, E.; Bellier, A.; Torii, R.; Werlein, C.; Jonigk, D. D.; Ackermann, M.; Dollman, K.; Lee, P. D.
10.1101/2023.10.09.561474 — pathology — Posted on 2023-10-10
3122 Telomeres control regulation of the human Telomerase (hTERT) gene through non-telomeric TRF2 and independent of Telomere looping
Sengupta, A.; Vinayagamurthy, S.; Soni, D.; Deb, R.; Mukherjee, A. K.; Dutta, S.; Jaiswal, J.; Yadav, M.; Sharma, S.; Bagri, S.; Roy, S. S.; Singh, A.; Khanna, D.; Bhatt, A. K.; Sharma, A.; Saurav, S.; Motiani, R. K.; Chowdhury, S.
10.1101/2023.10.09.561466 — cancer biology — Posted on 2023-10-10
3124 An interface-based molecular generative framework for protein-protein interaction inhibitors
Wang, J.; Mao, J.; Li, C.; Xiang, H.; Wang, X.; Wang, S.; Wang, Z.; Chen, Y.; Li, Y.; Sun, H.; No, K. T.; Song, T.; Zeng, X.
10.1101/2023.10.10.557742 — bioinformatics — Posted on 2023-10-10
3129 The commensal protist Tritrichomonas musculus exhibits a dynamic life cycle that induces extensive remodeling of the gut microbiota
Popovic, A.; Cao, E. Y.; Han, J.; Nursimulu, N.; Alves-Ferreira, E. V. C.; Burrows, K.; Kennard, A.; Alsmadi, N.; Grigg, M. E.; Mortha, A.; Parkinson, J.
10.1101/2023.03.06.528774 — microbiology — Posted on 2023-10-10
3130 Substructure of the brain's Cingulo-Opercular network
D'Andrea, C. B.; Laumann, T. O.; Newbold, D. J.; Nelson, S. M.; Nielsen, A. N.; Chauvin, R.; Marek, S.; Greene, D. J.; Dosenbach, N. U. F.; Gordon, E. M.
10.1101/2023.10.10.561772 — neuroscience — Posted on 2023-10-10
3136 Quinoa as Functional Food? Urinary elimination of ecdysterone after consumption of quinoa alone and in combination with spinach
Isenmann, E.; Yuliandra Yusuf, T.; Touvleliou, K.; Broekmann, M.; de la Torre, X.; Botre, F.; Diel, P.; Parr, M. K.
10.1101/2023.10.10.560427 — pharmacology and toxicology — Posted on 2023-10-10
3137 Stromal localization of inactive CD8+ T cells in metastatic mismatch repair deficient colorectal cancer
Kucukkose, E.; Baars, M. J. D.; Amini, M.; Schraa, S. J.; Floor, E.; Bol, G. M.; Rinkes, I. H. M. B.; Roodhart, J. M. L.; Koopman, M.; Laoukili, J.; Kranenburg, O.; Vercoulen, Y.
10.1101/2023.10.09.561039 — cancer biology — Posted on 2023-10-10
3138 CRISPR-Cas9 for selective targeting of somatic mutations in pancreatic cancers
Teh, S. S. K.; Bowland, K.; Bennett, A.; Halper-Stromberg, E.; Skaist, A.; Tang, J.; Cai, F.; Macoretta, A.; Liang, H.; Kamiyama, H.; Wheelan, S.; Lin, M.-T.; Hruban, R. H.; Scharpf, R. B.; Roberts, N. J.; Eshleman, J. R.
10.1101/2023.04.15.537042 — cancer biology — Posted on 2023-10-10
3143 Lactoylglutathione promotes inflammatory signaling in macrophages
Trujillo, M. N.; Jennings, E. Q.; Hoffman, E. A.; Zhang, H.; Phoebe, A. M.; Mastin, G. E.; Kitamura, N.; Reisz, J. A.; Megill, E.; Kantner, D.; Marcinkiewicz, M. M.; Twardy, S. M.; Lebario, F.; Chapman, E.; McCullough, R. L.; D'Alessandro, A.; Snyder, N. W.; Cusanovich, D.; Galligan, J. J.
10.1101/2023.10.10.561739 — biochemistry — Posted on 2023-10-10
3144 A maternal-effect Padi6 variant results in abnormal nuclear localization of DNMT1 and failure of epigenetic reprogramming and zygotic genome activation in mouse embryos
Giaccari, C.; Cecere, F.; Argenziano, L.; Galvao, A.; Acampora, D.; Rossi, G.; Hay Mele, B.; Cubellis, M. V.; Cerrato, F.; Andrews, S.; Cecconi, S.; Kelsey, G.; Riccio, A.
10.1101/2023.10.09.561545 — genomics — Posted on 2023-10-10
3145 Saltational episodes of reticulate evolution in the jumping pomace fly Drosophila saltans species group
Prediger, C.; Ferreira, E. A.; Zorzato, S. V.; Hua-Van, A.; Klasson, L.; Miller, W.; Yassin, A.; Madi-Ravazzi, L.
10.1101/2023.10.09.561511 — evolutionary biology — Posted on 2023-10-10
3146 Complex genomic landscape of inversion polymorphism in Europe's most destructive forest pest
Mykhailenko, A.; Zielinski, P.; Bednarz, A.; Schlyter, F.; Andersson, M. N.; Antunes, B.; Borowski, Z.; Krokene, P.; Melin, M.; Morales-Garcia, J.; Müller, J.; Nowak, Z.; Schebeck, M.; Stauffer, C.; Viiri, H.; Babik, W.; Nadachowska-Brzyska, K.
10.1101/2023.10.10.561670 — evolutionary biology — Posted on 2023-10-10
3148 The LCLAT1/LYCAT acyltransferase is required for EGF-mediated phosphatidylinositol-3,4,5-trisphosphate and Akt signalling
Chan, V.; Bone, L.; Anderson, K. E.; Zhang, K.; Orofiamma, L.; Awadeh, Y.; Lee, D. K. C.; Fu, N. J.; Chow, J. T. S.; Salmena, L.; Stephens, L. R.; Hawkins, P. T.; Antonescu, C. N.; Botelho, R. J.
10.1101/2023.01.26.524308 — cell biology — Posted on 2023-10-10
3149 The budding yeast heterochromatic protein Sir3 modulates genome-wide gene expression through transient direct contacts with euchromatin
Bhattacharjee, P.; Camasses, A.; Galic, H.; Hrgovcic, A.; Demont, L.; Nguyen, L. T.; Vasseur, P.; Radman-Livaja, M.
10.1101/603613 — molecular biology — Posted on 2023-10-10
3153 Decoding Internal Decision Making During Reverse Engineering Tasks
Marsh, B.; Rego, J.; Levy, M. M.; Sayer, M. P.; Waagen, A.; Barbieux, A.; Cranford, E. A.; Morrison, D. F.; Maldonado, F.; Johnson, J. P.; DiVita, J.; Buch, J. M.; Kim, T. H.-J.; Lebiere, C.; Fugate, S.; Bhattacharyya, R.
10.1101/2023.10.10.561734 — neuroscience — Posted on 2023-10-10
3155 Foveal drusen increase fixation instability: fixational eye movements as biomarkers for pre-symptomatic AMD
Murari, J.; Gautier, J.; Daout, J.; Krafft, L.; Senee, P.; Mece, P.; Seiple, W.; Grieve, K.; Sheynikhovich, D.; Meimon, S.; Paques, M.; Arleo, A.
10.1101/2023.10.09.560481 — neuroscience — Posted on 2023-10-10
3156 Ventral hippocampus neurons encode meal-related memory
Decarie-Spain, L.; Gu, C.; Tierno Lauer, L.; Subramanian, K. S.; Chehimi, S. N.; Kao, A. E.; Deng, I.; Bashaw, A. G.; Klug, M. E.; Hewage Galbokke, A.; Donohue, K. N.; Yang, M.; de Lartigue, G.; Myers, K. P.; Crist, R. C.; Reiner, B. C.; Hayes, M. R.; Kanoski, S.
10.1101/2023.10.10.561731 — neuroscience — Posted on 2023-10-10
3158 Striatal calcium transients detected by fiber photometry propagate to axons
Lipton, D. M.; Tamimi, M.; Shalom, I.; Sheinfeld, T.; Gonzales, B. J.; Groysman, M.; Citri, A.
10.1101/2023.10.09.560813 — neuroscience — Posted on 2023-10-10
3159 DNL343 is an investigational CNS penetrant eIF2B activator that prevents and reverses the effects of neurodegeneration caused by the Integrated Stress Response
Yulyaningsih, E.; Suh, J. H.; Fanok, M. H.; Chau, R.; Solanoy, H.; Takahashi, R.; Bakardjiev, A. I.; Becerra, I.; Benitez, N. B.; Chiu, C.-L.; Davis, S. S.; Dowdle, W. E.; Earr, T.; Estrada, A. E.; Gill, A.; Ha, C.; Haddick, P. C. G.; Henne, K. R.; Larhammar, M.; Leung, A. W.; Maciuca, R.; Memarzadeh, B.; Nguyen, H. N.; Nugent, A.; Osipov, M.; Ran, Y.; Rebadulla, K.; Roche, E.; Sandmann, T.; Wang, J.; Lewcock, J. W.; Scearce-Levie, K.; Kane, L. A.; Sanchez, P. E.
10.1101/2023.08.21.554203 — neuroscience — Posted on 2023-10-10
3161 The nonlinear meccano of hyperactivity in Alzheimer
Bonifazi, G.; Luchena, C.; Gaminde-Blasco, A.; Ortiz-Sanz, C.; Capetillo-Zarate, E.; Matute, C.; Alberdi, E.; De Pitta, M.
10.1101/2023.10.09.561541 — neuroscience — Posted on 2023-10-10
3162 The spatial extent of anatomical connections within the thalamus varies across the cortical hierarchy in humans and macaques
Howell, A. M.; Warrington, S.; Fonteneau, C.; Cho, Y. T.; Sotiropoulos, S.; Murray, J. D.; Anticevic, A.
10.1101/2023.07.22.550168 — neuroscience — Posted on 2023-10-10
3163 Shorter self-reported sleep duration in men is associated with worse virtual spatial navigation performance
Yavuz, E.; Lazar, A. S.; Gahnstrom, C. J.; Goodroe, S.; Coutrot, A.; Hornberger, M.; Spiers, H. J.
10.1101/2023.09.09.556942 — neuroscience — Posted on 2023-10-10
3164 Human foot outperforms the hand in mechanical pain discrimination
Ng, K. K. W.; Lafee, O.; Bouchatta, O.; Makdani, A. D.; Marshall, A. G.; Olausson, H.; McIntyre, S.; Nagi, S. S.
10.1101/2023.10.10.561422 — neuroscience — Posted on 2023-10-10
3165 Widespread drastic reduction of brain myelin content upon prolonged endurance exercise
Ramos-Cabrer, P.; Cabrera, A.; Padro, D.; Matute-Gonzalez, M.; Rodriguez-Antiguedad, A.; Matute, C.
10.1101/2023.10.10.561303 — neuroscience — Posted on 2023-10-10
3167 Gait adaptation to asymmetric hip stiffness applied by a robotic exoskeleton
Abdikadirova, B.; Price, M.; Moreno Jaramillo, J.; Hoogkamer, W.; Huber, M. E.
10.1101/2023.10.10.561679 — neuroscience — Posted on 2023-10-10
3169 Study-Phase Reinstatement: Encoding Spontaneous Thoughts as Memories
Halpern, D.; Lega, B.; Gross, R. E.; Sperling, M. R.; Wu, C.; Aronson, J. P.; Jobst, B. C.; Kahana, M. J.
10.1101/2023.10.04.560946 — neuroscience — Posted on 2023-10-10
3172 Bacteriophage-host interactions in microgravity onboard the International Space Station
Huss, P.; Chitboonthavisuk, C.; Meger, A.; Nishikawa, K.; Oates, R. P.; Mills, H.; Holzhaus, O.; Raman, S.
10.1101/2023.10.10.561409 — synthetic biology — Posted on 2023-10-10
3173 A K-mer based Bulked Segregant Analysis approach to map seed traits in unphased heterozygous potato genomes
Sonsungsan, P.; Nganga, M. L.; Lieberman, M.; Amundson, K.; Steward, V.; Plaimas, K.; Comai, L.; Henry, I. M.
10.1101/2023.10.09.561609 — plant biology — Posted on 2023-10-10
3174 A Computational Model Predicts Sex-specific Responses to Calcium Channel Blockers in Mesenteric Vascular Smooth Muscle
Hernandez Hernandez, G.; O'Dwyer, S. C.; Matsumoto, C.; Tieu, M.; Fong, Z.; Yang, P.-C.; Lewis, T. J.; Santana, L. F.; Clancy, C. E.
10.1101/2023.06.24.546394 — physiology — Posted on 2023-10-10
3175 Convergent Epigenetic Evolution Drives Relapse in Acute Myeloid Leukemia
Nuno, K.; Azizi, A.; Koehnke, T.; Lareau, C.; Ediriwickrema, A.; Corces, M. R.; Satpathy, A. T.; Majeti, R.
10.1101/2023.10.10.561642 — cancer biology — Posted on 2023-10-10
3176 Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation
Zhang, A. M. Y.; Xia, Y. H.; Lin, J. S. H.; Chu, K. H.; Wang, W. C. K.; Ruiter, T. J. J.; Yang, J. C. C.; Chen, N.; Chhuor, J.; Patil, S.; Cen, H. H.; Rideout, E.; Richard, V. R.; Schaeffer, D. F.; Zahedi, R. P.; Borchers, C. H.; Johnson, J. D.; Kopp, J.
10.1101/2022.05.06.490845 — cancer biology — Posted on 2023-10-10
3181 SC2MeNetDrug: A computational tool to uncover inter-cell signaling targets and identify relevant drugs based on single cell RNA-seq data
Feng, J.; Goedegebuure, S. P.; Zeng, A.; Bi, Y.; Wang, T.; Payne, P. R.; Ding, L.; DeNardo, D.; Hawkins, W.; Fields, R. C.; Li, F.
10.1101/2021.11.15.468755 — bioinformatics — Posted on 2023-10-10
3183 Shared and Distinct Mechanisms of UBA1 Inactivation Across Different Diseases
Collins, J. C.; Magaziner, S. J.; English, M.; Hassan, B.; Chen, X.; Balanda, N.; Anderson, M.; Lam, A.; Fernandez-Pol, S.; Kwong, B.; Greenberg, P. L.; Terrier, B.; Likhite, M. E.; Kosmider, O.; Wang, Y.; Samara, N. L.; Walters, K. J.; Beck, D. B.; Werner, A.
10.1101/2023.10.10.561769 — biochemistry — Posted on 2023-10-10
3184 Inhibition of Asparagine Synthetase Effectively Retards Polycystic Kidney Disease Progression
Podrini, C.; Clerici, S.; Tronci, L.; Stefanoni, D.; Canu, T.; Chiaravalli, M.; Spies, D.; Costa, A. S. H.; Esposito, A.; D'Alessandro, A.; Frezza, C.; Bachi, A.; Boletta, A.
10.1101/2023.10.10.561720 — biochemistry — Posted on 2023-10-10
3185 27-hydroxylation of oncosterone by CYP27A1 switches its activity from pro-tumor to anti-tumor
Ayadi, S.; Friedrichs, S.; Soules, R.; Pucheu, L.; Luetjohann, D.; Silvente-Poirot, S.; Poirot, M.; de Medina, P.
10.1101/2023.10.10.560948 — biochemistry — Posted on 2023-10-10
3186 Efficacy of the first bioactive peptide from the pearl
Wu, C.; Yin, Z.; Wang, Y.; Chen, X.; Li, B.; Wang, Q.; Yao, L.; Zhang, Z.; Liu, X.; Zhang, R.
10.1101/2023.10.10.561660 — biochemistry — Posted on 2023-10-10
3187 Discovery of novel microRNA mimic repressors of ribosome biogenesis
Bryant, C. J.; McCool, M. A.; Rosado-Gonzalez, G. T.; Abriola, L.; Surovtseva, Y. V.; Baserga, S. J.
10.1101/2023.02.17.526327 — biochemistry — Posted on 2023-10-10
3194 Amur grape genome sequence
Wang, P.; Meng, F.; Yang, Y.; Mu, Q.; Ding, T.; Liu, H.-P.; Wang, F.; Li, A.; Zhang, Q.; Fan, S.; Li, B.; Ma, Z.; Zhang, T.; Zhou, Y.; Zhao, H.; Wang, X.
10.1101/2023.10.09.561595 — genomics — Posted on 2023-10-10
3197 Chromosome-scale Genome Assembly of Lewis Flax (Linum lewisii Pursh.)
Innes, P. A.; Smart, B. C.; Barham, J. A.; Hulke, B.; Kane, N. C.
10.1101/2023.10.10.561607 — genomics — Posted on 2023-10-10
3202 Unveiling the ecology, taxonomy and metabolic capabilities of MBA03, a potential key player in anaerobic digestion
Puchol-Royo, R.; Pascual, J.; Ortega-Legarreta, A.; Otto, P.; Tideman, J.; de Vries, S.-J.; Abendroth, C.; Tanner, K.; Porcar, M.; Latorre-Perez, A.
10.1101/2023.09.08.556800 — ecology — Posted on 2023-10-10
3203 BirthSeq, a new method to isolate and analyze dated cells from any tissue in vertebrates
Rueda-Alana, E.; Grillo, M.; Vazquez, E.; Marco Salas, S.; Senovilla-Ganzo, R.; Escobar, L.; Quintas, A.; Benguria, A.; Aransay, A. M.; Dopazo, A.; Encinas, J. M.; Nilsson, M.; Garcia-Moreno, F.
10.1101/2023.10.10.559090 — developmental biology — Posted on 2023-10-10
3205 Divergent evolutionary strategies preempt tissue collision in fly gastrulation
Dey, B.; Kaul, V.; Kale, G.; Scorcelletti, M.; Takeda, M.; Wang, Y.-C.; Lemke, S.
10.1101/2023.10.09.561568 — developmental biology — Posted on 2023-10-10
3206 Modeling Sepsis-Associated ARDS Using a Lung Endothelial Microphysiological System
Liang, N.-W.; Wilson, C.; Davis, B. C.; Wolf, I.; Qyli, T.; Moy, J.; Schnapp, L. M.; Beebe, D. J.; Kerr, S. C.; Faust, H. E.
10.1101/2023.10.10.561102 — cell biology — Posted on 2023-10-10
3207 SHIFTR enables the unbiased and multiplexed identification of proteins bound to specific RNA regions in live cells
Aydin, J.; Gabel, A.; Zielinski, S.; Ganskih, S.; Schmidt, N.; Hartigan, C. R.; Schenone, M.; Carr, S. A.; Munschauer, M.
10.1101/2023.10.09.561498 — molecular biology — Posted on 2023-10-10
3210 Beta-catenin-mediated activation of Wnt target genes utilizes a biomolecular condensate-dependent mechanism
Stewart, R. A.; Goodman, L. B.; Tran, J. J.; Zientko, J. P.; Sabu, M.; Jeon, U. S.; Cadigan, K. M.
10.1101/2023.10.09.561634 — molecular biology — Posted on 2023-10-10
3214 A label-free approach for relative spatial quantitation of c-di-GMP in microbial biofilms
McCaughey, C.; Trebino, M.; McAtamney, A.; Isenberg, R.; Mandel, M. J.; Yildiz, F.; Sanchez, L.
10.1101/2023.10.10.561783 — microbiology — Posted on 2023-10-10
3215 SARS-CoV-2 antibodies cross-react and enhance dengue infection
Jakhar, K.; Sonar, S.; Singh, G.; Sarkar, T.; Tiwari, M.; Kaur, J.; Rathore, D. K.; Lal, B.; Kumar, S.; Srivastav, P.; Kumar, S.; Phagna, V.; Kumar, L.; Gupta, V.; Kshetrapal, P.; Singh, S.; Wadhwa, N.; Thiruvengadam, R.; Raghavan, S.; Gosain, M.; Shrivastava, T.; Bhattacharyya, S.; Bhattacharya, J.; Asthana, S.; Mani, S.
10.1101/2023.10.09.557914 — immunology — Posted on 2023-10-10
3218 Large genetic analysis of alcohol resistance and tolerance reveals an inverse correlation and suggests "true" tolerance mutants.
Chvilicek, M. M.; Seguin, A.; Lathen, D. R.; Titos, I.; Cummins-Beebe, P. N.; Pabon, M. A.; Miscevic, M.; Nickel, E. A.; Merrill, C. B.; Rodan, A. R.; Rothenfluh, A.
10.1101/2023.10.09.561599 — neuroscience — Posted on 2023-10-10
3219 In vivo disentanglement of diffusion frequency-dependence, tensor shape, and relaxation using multidimensional MRI
Johnson, J. T. E.; Irfanoglu, M. O.; Manninen, E.; Ross, T. J.; Yang, Y.; Laun, F. B.; Martin, J.; Topgaard, D.; Benjamini, D.
10.1101/2023.10.10.561702 — neuroscience — Posted on 2023-10-10
3222 Phosphoglycerate kinase 1 is a central leverage point in Parkinson's disease driven neuronal metabolic deficits
Kokotos, A.; Antoniazzi, A.; Unda, S.; Kokotos, M. S.; Park, D.; Eliezer, D.; Kaplitt, M.; De Camilli, P.; Ryan, T.
10.1101/2023.10.10.561760 — neuroscience — Posted on 2023-10-10
3223 Neurogenesis-mediated circuit remodeling reduces engram reinstatement and promotes forgetting
Guskjolen, A.; Dhaliwal, J.; de la Parra, J.; Epp, J. R.; Ko, S.; Chahley, E.; de Snoo, M.; Solari, M.; Panesar, P.; Snyder, J. S.; Duan, X.; Sanes, J.; Josselyn, S.; Frankland, P.
10.1101/2023.10.10.561722 — neuroscience — Posted on 2023-10-10
3228 Shifts in attention drive context-dependent subspace encoding in anterior cingulate cortex during decision making
Hajnal, M. A.; Tran, D.; Szabo, Z.; Albert, A.; Safaryan, K.; Einstein, M.; Martelo, M. V.; Polack, P.-O.; Golshani, P.; Orban, G.
10.1101/2023.10.10.561737 — neuroscience — Posted on 2023-10-10
3229 When random variation results in functional significance
Barfield, J. H.; Kells, P. A.; Gautam, S. H.; Li, J.; Shew, W.
10.1101/2023.10.10.555393 — neuroscience — Posted on 2023-10-10
3230 Educational Environment and White Matter Development in Early Adolescence
Roy, E.; Van Rinsveld, A.; Nedelec, P.; Richie-Halford, A.; Rauschecker, A. M.; Sugrue, L. P.; Rokem, A.; McCandliss, B. D.; Yeatman, J. D.
10.1101/2023.10.10.561784 — neuroscience — Posted on 2023-10-10
3231 Cell type-focused compound screen in human organoids reveals molecules and pathways controlling cone photoreceptor death
Spirig, S. E.; Arteaga-Moreta, V. J.; Raics, Z.; Posada-Cespedes, S.; Chreng, S.; Galuba, O.; Galuba, I.; Claerr, I.; Renner, S.; Kleindienst, T.; Volak, A.; Imbach, J.; Malysheva, S.; Siwicki, R. A.; Hahaut, V.; Hou, Y.; Picelli, S.; Cattaneo, M.; Jüttner, J.; Cowan, C. S.; Duckely, M.; Baeschlin, D. K.; Renner, M.; Unterreiner, V.; Roska, B.
10.1101/2023.10.09.561525 — neuroscience — Posted on 2023-10-10
3232 Brain state and cortical layer-specific mechanisms underlying perception at threshold
Morton, M. P.; Denagamage, S.; Blume, I. J.; Reynolds, J. H.; Jadi, M. P.; Nandy, A. S.
10.1101/2021.11.16.468866 — neuroscience — Posted on 2023-10-10
3233 Menstrual cycle-driven hormone concentrations co-fluctuate with white and grey matter architecture changes across the whole brain
Rizor, E. J.; Babenko, V.; Dundon, N. M.; Beverly-Aylwin, R.; Stump, A.; Hayes, M.; Herschenfeld-Catalan, L.; Jacobs, E. G.; Grafton, S. T.
10.1101/2023.10.09.561616 — neuroscience — Posted on 2023-10-10
3234 Long-term human organotypic brain slice cultures: a detailed protocol to provide a comprehensive framework for single-neuron and neuronal network investigations
Bak, A.; Koch, H.; van Loo, K. M. J.; Schmied, K.; Gittel, B.; Weber, Y. G.; Schwarz, N.; Tauber, S. C.; Wuttke, T. V.; Delev, D.
10.1101/2023.10.10.561508 — neuroscience — Posted on 2023-10-10
3235 Threat-dependent scaling of prelimbic dynamics to enhance fear representation
Casanova, J. P.; Pouget, C.; Treiber, N.; Agarwal, I.; Brimble, M. A.; Vetere, G.
10.1101/2023.10.10.561506 — neuroscience — Posted on 2023-10-10
3236 Cerebellar interneuron activity is triggered by reach endpoint during learning of a complex locomotor task
Andrianarivelo, A.; Stein, H.; Gabillet, J.; Batifol, C.; Jalil, A.; Cayco Gajic, N. A.; Graupner, M.
10.1101/2023.10.10.561690 — neuroscience — Posted on 2023-10-10
3237 Aminergic and peptidergic modulation of Insulin-Producing Cells in Drosophila
Held, M.; Bisen, R. S.; Zandawala, M. M.; Chockley, A. S.; Balles, I. S.; Hilpert, S.; Liessem, S.; Cascino-Milani, F.; Ache, J. M.
10.1101/2023.09.14.557555 — neuroscience — Posted on 2023-10-10
3238 Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver Identifies Tissue- and Sex-Specific Changes with Implications for Genomic Imprinting
Morgan, R. K.; Wang, K.; Svoboda, L. K.; Rygiel, C. A.; Lalancette, C.; Cavalcante, R.; Bartolomei, M. S.; Prasasya, R. D.; Neier, K.; Perera, B. P.; Jones, T. R.; Colacino, J. A.; Sartor, M. A.; Dolinoy, D. C.
10.1101/2023.09.29.560131 — pharmacology and toxicology — Posted on 2023-10-10
3240 Molecular mechanisms of liposome interactions with bacterial envelopes
Scheeder, A.; Brockhoff, M.; Ward, E.; Kaminski Schierle, G. S.; Mela, I.; Kaminski, C. F.
10.1101/2023.10.07.561336 — biophysics — Posted on 2023-10-10
3242 Climate warming suppresses soil abundant fungal taxa and reduces soil carbon efflux in a semi-arid grassland
Qiu, Y.; Zhang, K.; Zhao, Y.; Zhao, Y.; Wang, B.; Wang, Y.; He, T.; Xu, X.; Bai, T.; Zhang, Y.; Hu, S.
10.1101/2023.10.08.561373 — ecology — Posted on 2023-10-10
3243 TAF7L REGULATES EARLY STAGES OF MALE GERM CELL DEVELOPMENT
Moreno Irusta, A.; Dominguez, E. M.; Iqbal, K.; Zhang, X.; Wang, N.; Soares, M. J.
10.1101/2023.10.08.561408 — developmental biology — Posted on 2023-10-10
3246 Elucidating Compound Mechanism of Action and Polypharmacology with a Large-scale Perturbational Profile Compendium
Hu, L. Z.; Douglass, E.; Turunen, M.; Pampou, S.; Grunn, A.; Realubit, R.; Antolin, A. A.; Wang, A. L. E.; Li, H.; Subramaniam, P.; Karan, C.; Alvarez, M.; Califano, A.
10.1101/2023.10.08.561457 — systems biology — Posted on 2023-10-10
3247 The fitness cost of spurious phosphorylation
Bradley, D.; Hogrebe, A.; Dandage, R.; Dube, A. K.; Leutert, M.; Dionne, U.; Chang, A.; Villen, J.; Landry, C. R.
10.1101/2023.10.08.561337 — systems biology — Posted on 2023-10-10
3249 The impact of short-lived controls on the interpretation of lifespan experiments and progress in geroscience
Pabis, K. K.; Barardo, D.; Gruber, J.; Sirbu, O.; Selvarajoo, K.; Kaeberlein, M.; Kennedy, B. K.
10.1101/2023.10.08.561459 — physiology — Posted on 2023-10-10
3252 Exploration of the Tunability of BRD4 Degradation by DCAF16 Trans-labelling Covalent Glues
Hassan, M. M.; Li, Y.-D.; Ma, M. W.; Teng, M.; Byun, W. S.; Puvar, K.; Lumpkin, R.; Sandoval, B.; Rutter, J. C.; Jin, C. Y.; Wang, M. Y.; Xu, S.; Schmoker, A. M.; Cheong, H.; Groendyke, B. J.; Qi, J.; Fischer, E. S.; Ebert, B. L.; Gray, N.
10.1101/2023.10.07.561308 — pharmacology and toxicology — Posted on 2023-10-10
3253 Fluorescent pH-sensing bandage for point-of-care wound diagnostics
Al-Hawat, M.-L.; Tricou, L.-P.; Cherifi, K.; Lamontagne, S.; Tran, M.; Ching Yie Ngu, A.; Manrique, G.; Guirguis, N.; Israel Machuca-Parra, A.; Matoori, S.
10.1101/2023.10.08.561402 — pharmacology and toxicology — Posted on 2023-10-10
3256 Oscillatory traveling waves reveal predictive coding abnormalities in schizophrenia
Alamia, A.; Gordillo, D.; Chkonia, E.; Roinishvili, M.; Cappe, C.; Herzog, M. H.
10.1101/2023.10.09.561490 — neuroscience — Posted on 2023-10-10
3258 Unlocking DNA Damage Sensitivity of Cancer Cells: The Potential of Splicing Inhibitors
Anufrieva, K. S.; Lukina, M. M.; Ivanova, O. M.; Kazakova, A. N.; Shnaider, P. V.; Klimina, K. M.; Veselovsky, V. A.; Luzhin, A. V.; Velichko, A. K.; Kantidze, O. L.; Mochalova, E. N.; Nikitin, M. P.; Kashina, A. V.; Vasilchikova, E. A.; Deev, R. V.; Emelin, A. M.; Turchin, A. N.; Liu, Z.; Wang, Z.; Boichenko, V. S.; Markina, N. M.; Lagarkova, M. A.; Govorun, V. M.; Arapidi, G. P.; Shender, V. O.
10.1101/2023.10.08.561421 — cancer biology — Posted on 2023-10-10
3260 Motion Blur Microscopy
Goreke, U.; Gonzales, A.; Shipley, B.; Man, Y.; Wulftange, W.; An, R.; Hinczewski, M.; Gurkan, U. A.
10.1101/2023.10.08.561435 — biophysics — Posted on 2023-10-10
3263 BRD2 and BRD3 genes independently evolved RNA structures to control unproductive splicing
Petrova, M.; Margasyuk, S.; Vorobeva, M.; Skvortsov, D.; Dontsova, O.; Pervouchine, D.
10.1101/2023.10.08.561383 — bioinformatics — Posted on 2023-10-10
3266 Instant Assembly of Collagen for Scaffolding, Tissue Engineering, and Bioprinting
Gong, X.; Wen, Z.; Liang, Z.; Xiao, H.; Lee, S.; Wright, T.; Nguyen, R. Y.; Rossello, A.; Mak, M.
10.1101/2023.10.08.561456 — bioengineering — Posted on 2023-10-10
3269 Population genomic analysis reveals genetic structure and thermal-tolerant genotypes in remnant Tasmanian giant kelp populations
Iha, C.; Layton, C.; Amancio, C. E.; Flentje, W.; Lenton, A.; Fraser, C. I.; Johnson, C. R.; Willis, A.
10.1101/2023.10.08.561451 — genetics — Posted on 2023-10-10
3274 Delivery of A Jagged1-PEG-MAL hydrogel with Pediatric Human Bone Cells Regenerates Critically-Sized Craniofacial Bone Defects
Kamalakar, A.; Tobin, B.; Kaimari, S.; Toma, A. I.; Moriarity, I.; Gautam, S.; Bhattaram, P.; Abramowicz, S.; Drissi, H.; Garcia, A.; Wood, L.; Goudy, S. L.
10.1101/2023.10.06.561291 — developmental biology — Posted on 2023-10-10
3277 Developmental origin and local signals cooperate to determine septal astrocyte identity
Xie, Y.; Reid, C. M.; Granados, A. A.; Garcia, M. T.; Dale-Huang, F.; Hanson, S. M.; Leon, W. R. M.; Liu, J.; Adam, M. A.; Mosto, O.; Pisco, A. O.; Alvarez-Buylla, A.; Harwell, C. C.
10.1101/2023.10.08.561428 — neuroscience — Posted on 2023-10-10
3278 Effect of altered production and storage of dopamine on development and behavior in C. elegans
Lee, I.; Knickerbocker, A.; Depew, C.; Martin, E.; Dicent, J.; Miller, G. W.; Bucher, M. L.
10.1101/2023.10.07.561350 — neuroscience — Posted on 2023-10-10
3279 Multi-omics analysis reveals novel interplays between intratumoral bacteria and glioma
Li, T.; Zhao, Z.; Peng, M.; Wang, C.; Luo, F.; Zeng, M.; Sun, K.; Fang, Z.; Luo, Y.; Huang, Q.; Xie, Y.; Wang, J.; Huang, J.-D.; Zhou, H.; Sun, H.
10.1101/2023.10.08.561332 — neuroscience — Posted on 2023-10-10
3283 A cardiotonic steroid multiplex method using ultra-high-performance liquid chromatography-tandem mass spectrometry
Gilligan, L. C.; Alamrani, D.; Fobian, D.; Kotecha, D.; Kirchhof, P.; Arlt, W.; Taylor, A. E.; Pavlovic, D.
10.1101/2023.10.07.561354 — physiology — Posted on 2023-10-10
3286 The Minimal Dataset for Cancer of the 1+Million Genomes Initiative
Riba, M.; Sala, C.; Culhane, A.; Flobak, A.; Patocs, A.; Boye, K.; Plevova, K.; Pospisilova, S.; Gandolfi, G.; Morelli, M.; Bucci, G.; Edsjo, A.; Lassen, U.; Al-Shahrour, F.; Lopez-Bigas, N.; Hovland, R.; Cuppen, E.; Valencia, A.; Antoine-Poirel, H.; Rosenquist Brandell, R.; Scollen, S.; Arenas Marquez, J.; Belien, J.; De Nicolo, A.; De Maria, R.; Torrents, D.; Tonon, G.
10.1101/2023.10.07.561259 — cancer biology — Posted on 2023-10-10
3288 HIPSD&R-seq enables scalable genomic copy number and transcriptome profiling
Lazareva, O.; Malm, J. P.; Simovic-Lorenz, M.; Philippos, G.; Sant, P.; Parekh, U.; Hammann, L.; Li, A.; Yildiz, U.; Marttinen, M.; Zaugg, J. B.; Noh, K. M.; Stegle, O.; Ernst, A.
10.1101/2023.10.09.561487 — cancer biology — Posted on 2023-10-10
3289 Adaptation to volumetric compression drives hepatoblastoma cells to an apoptosis-resistant and invasive phenotype
Gong, X.; Ogino, N.; Leite, M. F.; Chen, Z.; Liu, R.; Kruglov, E.; Flores, K.; Cabral, A.; Mendes, G. M. M.; Ehrlich, B. E.; Mak, M.
10.1101/2023.10.08.561453 — cancer biology — Posted on 2023-10-10
3290 A coarse-grained model of glycosaminoglycans for biomolecular simulation
Shivgan, A. T.; Marzinek, J. K.; Krah, A.; Matsudaira, P.; Verma, C. S.; Bond, P. J.
10.1101/2023.10.06.561318 — biophysics — Posted on 2023-10-10
3296 In silico approaches to identify the role of lncRNAs in Prostate cancer and Androgen receptor-targeted proteins
Khilwani, B.; Kour, B.; Shukla, N.; R, B.; Vuree, S.; Ansari, A. S.; Lohiya, N. K.; Suravajhala, R.; Suravajhala, P.
10.1101/2023.10.07.561330 — bioinformatics — Posted on 2023-10-10
3297 Scaling cross-tissue single-cell annotation models
Fischer, F.; Fischer, D. S.; Biederstedt, E.; Villani, A.-C.; Theis, F. J.
10.1101/2023.10.07.561331 — bioinformatics — Posted on 2023-10-10
3305 Complete suspension culture of human induced pluripotent stem cells supplemented with suppressors of spontaneous differentiation
Matsuo-Takasaki, M.; Kambayashi, S.; Hemmi, Y.; Wakabayashi, T.; Shimizu, T.; An, Y.; Takauchi, K.; Ibuki, M.; Kawai, Y.; Umekage, M.; Kato, T. M.; Noguchi, M.; Nakade, K.; Nakamura, Y.; Nakaishi, T.; Tsukahara, M.; Hayashi, Y.
10.1101/2023.10.08.561419 — bioengineering — Posted on 2023-10-10
3308 Landscape of Large-Scale Somatic Genomic Insertions in Non-Small Cell Lung Carcinoma Revealed by Nanopore Sequencing
Xie, D.; Xia, L.; Wang, Z.; Zeng, T.; Wang, H.; PI, X.; Zhu, G.; Wu, X.; Li, Y.; Den, Y.; Qi, Y.; Liu, X.; Zhang, F.; Li, W.
10.1101/2023.10.07.561149 — genomics — Posted on 2023-10-10
3312 CH4 transport in wetland plants under controlled environmental conditions: untangling the impacts of phenology
Ge, M.; Korrensalo, A.; Putkinen, A.; Laiho, R.; Kohl, L.; Pihlatie, M.; Lohila, A.; Makiranta, P.; Siljanen, H.; Tuittila, E.-S.; Koskinen, M.
10.1101/2023.10.08.561392 — ecology — Posted on 2023-10-10
3313 Visualisation of gene expression within the context of tissues: an X-ray computed tomography-based multimodal approach
Kairiss, K.; Sokolova, N.; Zilova, L.; Schlagheck, C.; Reinhardt, R.; Baumbach, T.; Farago, T.; van de Kamp, T.; Wittbrodt, J.; Weinhardt, V.
10.1101/2023.10.09.561491 — developmental biology — Posted on 2023-10-10
3315 Sustained bacterial (N2O) reduction at acidic pH
He, G.; Chen, G.; Xie, Y.; Swift, C.; Cha, G.; Konstantinidis, K. T.; Radosevich, M.; Löffler, F. E.
10.1101/2023.10.06.560748 — microbiology — Posted on 2023-10-10
3316 Deep learning-guided selection of antibody therapies with enhanced resistance to current and prospective SARS-CoV-2 Omicron variants
Frei, L.; Gao, B.; Han, J.; Taft, J. M.; Irvine, E. B.; Weber, C. R.; Kumar, R.; Eisinger, B.; Reddy, S. T.
10.1101/2023.10.09.561492 — immunology — Posted on 2023-10-10
3319 Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells
Chen, Y.; Lee, J. H. H.; Li, J.; Park, S.; Perez-Flores, M. C.; Peguero, B.; Kersigo, J.; Kang, M.; Choi, J.; Levine, L.; Gratton, M. A.; Friztsch, B.; Yamoah, E. N.
10.1101/2023.10.08.561387 — neuroscience — Posted on 2023-10-10
3320 PSEN1-M146V and PSEN1-A246E mutations associated with Alzheimers disease impair proper microglia differentiation
Aubert, A.; Mendoza-Ferri, M.-G.; Bramoulle, A.; Studer, F.; Colombo, B. M.; Mendoza-Parra, M. A.
10.1101/2023.10.08.561397 — neuroscience — Posted on 2023-10-10
3321 Archaeal origin translation proofreader imparts multialdehyde stress tolerance to land plants
Kumar, P.; Roy, A.; Mukul, S. J.; Singh, A. K.; Singh, D. K.; Nalli, A.; Banerjee, P.; Babu, K. S. D.; Raman, B.; Kruparani, S. P.; Siddiqi, I.; Sankaranarayanan, R.
10.1101/2023.10.06.561280 — plant biology — Posted on 2023-10-10
3322 Mouse Model of Heart Attack and Stroke Shows Improved Survival with MPO Inhibition
Shamsuzzaman, S.; Deaton, R. A.; Doviak, H.; Evans, M.; Salamon, A.; Karnewar, S.; Serbulea, V.; Alencar, G. F.; Shankman, L. S.; Walsh, K.; Bekiranov, S.; Kocher, O.; Kreiger, M.; Kull, B.; Persson, M.; Bergenhem, N.; Heydarkhan-Hagvall, S.; Owens, G. K.
10.1101/2023.10.06.561304 — physiology — Posted on 2023-10-10
3324 A sexually dimorphic hepatic cycle of very low density lipoprotein uptake and assembly
Martini, T.; Gobet, C.; Salati, A.; Blanc, J.; Mookhoek, A.; Knott, G.; Sordet-Dessimoz, J.; Naef, F.
10.1101/2023.10.07.561324 — physiology — Posted on 2023-10-10
3325 A red-emitting carborhodamine for monitoring and measuring membrane potential
Gest, A. M. M.; Lazzari-Dean, J. R.; Ortiz, G.; Yaeger-Weiss, S. K.; Boggess, S. C.; Miller, E. W.
10.1101/2023.10.06.561080 — physiology — Posted on 2023-10-10
3329 Detection of disease-specific signatures in B cell repertoires of lymphomas using machine learning
Schmidt-Barbo, P.; Kalweit, G.; Naouar, M.; Paschold, L.; Willscher, E.; Schultheiss, C.; Markl, B.; Dirnhofer, S.; Tzankov, A.; Binder, M.; Kalweit, M.
10.1101/2023.10.05.561150 — bioinformatics — Posted on 2023-10-10
3331 A wave of minor de novo DNA methylation initiates in mouse 8-cell embryos and co-regulates imprinted X- chromosome inactivation
Yue, Y.; Fu, W.; Yang, Q.; Zhang, C.; Wenjuan Wang, W. w.; Chu, M.; Lyu, Q.; Tang, Y.; Cui, J.; Wang, X.; Zhang, Z.; Tian, J.; An, L.
10.1101/2023.10.06.561284 — developmental biology — Posted on 2023-10-10
3333 Tim-1 and Tim-4 mediate entry of the human Kaposi's sarcoma-associated herpesvirus and the related rhesus monkey rhadinovirus
Scribano, S.; Schlagowski, S.; Liu, S.; Fricke, T.; Yang, X.; Neipel, F.; Grosskopf, A. K.; Hornich, B. F.; Ensser, A.; Hahn, A. S.
10.1101/2023.10.10.561662 — microbiology — Posted on 2023-10-10
3334 Deep generative models predict SARS-CoV-2 Spike infectivity and foreshadow neutralizing antibody escape
Youssef, N. A.; Ghantous, F.; Gurev, S.; Brock, K.; Jaimes, J. A.; Dauphin, A.; Yurkovetskiy, L.; Soto, D.; Estaboulieh, R.; Kotzen, B.; Bosso, M.; Lemieux, J.; Luban, J. A.; Seaman, M.; Marks, D.
10.1101/2023.10.08.561389 — immunology — Posted on 2023-10-10
3335 IL-33-binding HpARI family homologues with divergent effects in suppressing or enhancing Type 2 immune responses
Colomb, F.; Ogunkanbi, A.; Jamwal, A.; Dong, B.; Maizels, R. M.; Finney, C. A.; Wasmuth, J. D.; Higgins, M.; McSorley, H.
10.1101/2023.10.09.561567 — immunology — Posted on 2023-10-10
3336 Suppression of epithelial proliferation and tumorigenesis by immunoglobulin A
Donaldson, G. P.; Reis, G. L.; Saad, M.; Mamede, I.; Chen, G.; DelGaudio, N. L.; Zhang, D.; Aydin, B.; Harrer, C. E.; Castro, T. B. R.; Grivennikov, S.; Reis, B. S.; Stadtmueller, B. M.; Victora, G. D.; Mucida, D.
10.1101/2023.10.06.561290 — immunology — Posted on 2023-10-10
3337 Time- and lineage-resolved transcriptional profiling uncovers gene expression programs and clonal relationships that underlie human T lineage specification
Michaels, Y. S.; Major, M. C.; Bonham-Carter, B.; Zhang, J.; Heydari, T.; Edgar, J. M.; Greenstreet, L.; Vilarrasa-Blasi, R.; Kim, S.; Castle, E. L.; Forrow, A.; Ibanez-Rios, M. I.; Zimmerman, C.; Chung, Y.; Stach, T.; Werschler, N.; Knapp, D. J.; Vento-Tormo, R.; Schiebinger, G.; Zandstra, P. W.
10.1101/2023.10.06.561277 — immunology — Posted on 2023-10-10
3339 A novel HIV triple broadly neutralizing antibody (bNAb) combination-based passive immunization of infant rhesus macaques achieves durable protective plasma neutralization levels and mediates anti-viral effector functions.
Dankwa, S.; Kosman, C.; Dennis, M.; Giorgi, E. E.; Vuong, K.; Pahountis, I.; Garza, A.; McCarthy, J.; Mayer, B. T.; Ngo, J. T.; Enemuo, C. A.; Carnathan, D. G.; Stanfield-Oakley, S.; Berendam, S. J.; Weinbaum, C.; Engelman, K.; Magnani, D. M.; Chan, C.; Ferrari, G.; Silvestri, G.; Amara, R. R.; Chahroudi, A.; Permar, S. R.; Fouda, G. G.; Goswami, R.
10.1101/2023.10.09.561559 — immunology — Posted on 2023-10-10
3342 A neural mechanism for learning from delayed postingestive feedback
Zimmerman, C. A.; Pan-Vazquez, A.; Wu, B.; Keppler, E. F.; Guthman, E. M.; Fetcho, R. N.; Bolkan, S. S.; McMannon, B.; Lee, J.; Hoag, A. T.; Lynch, L. A.; Janarthanan, S. N.; Lopez Luna, J. F.; Bondy, A. G.; Falkner, A. L.; Wang, S. S.-H.; Witten, I. B.
10.1101/2023.10.06.561214 — neuroscience — Posted on 2023-10-10
3345 Nanoscale Structural Mapping of Protein Aggregates in Live Cells Modeling Huntington's Disease
Guo, Z.; Chiesa, G.; Yin, J.; Sanford, A.; Meier, S. J.; Khalil, A. S.; Cheng, J.-X.
10.1101/2023.10.09.561223 — biophysics — Posted on 2023-10-10
3346 Multifunction Fluorescence Open-Source In Vivo/In Vitro Imaging System (openIVIS)
Branning, J. M.; Faughnan, K. A.; Tomson, A. A.; Bell, G. J.; Isbell, S. M.; DeGroot, A.; Jameson, L.; Kilroy, K.; Smith, M.; Smith, R.; Mottel, L.; Branning, E. G.; Warrall, Z.; Anderson, F.; Panditaradyula, A.; Yang, W.; Abdelmalek, J.; Brake, J.; Cash, K. J.
10.1101/2023.10.06.561111 — bioengineering — Posted on 2023-10-10
3348 Trafficking dynamics of VEGFR1, VEGFR2, and NRP1 in human endothelial cells
Sarabipour, S.; Kinghorn, K.; Quigley, K. M.; Kovacs-Kasa, A.; Annex, B. H.; Bautch, V. L.; Mac Gabhann, F.
10.1101/2022.09.30.510412 — systems biology — Posted on 2023-10-10
3354 Multi-omic profiling of pathogen-stimulated primary immune cells
Salz, R.; Vorsteveld, E. E.; van der Made, C. I.; Kersten, S.; Stemerdink, M.; Hsieh, T.; Mhlanga, M.; Netea, M.; Volders, P.-J.; Hoischen, A.; 't Hoen, P. A. C.
10.1101/2023.09.13.557514 — immunology — Posted on 2023-10-10
3356 Aboveground enemy release increases seedling survival in grasslands
Brian, J. I.; Shepherd, H. E. R.; Perez-Navarro, M. A.; Catford, J. A.
10.1101/2023.10.06.561247 — plant biology — Posted on 2023-10-10
3357 Optimization for High-Throughput BiFC screening
Jia, Y.; Reboulet, J.; Dumont, A.; Ruscio, S. D.; Gillet, B.; Hughes, S.; Bleicher, F.; Merabet, S.
10.1101/2023.10.09.561405 — bioengineering — Posted on 2023-10-10
3359 Regulation of multiple signaling pathways promotes the consistent expansion of human pancreatic progenitors in defined conditions
Jarc, L.; Bandral, M.; Zanfrini, E.; Lesche, M.; Kufrin, V.; Sendra, R.; Pezzolla, D.; Yiannios, I.; Khattak, S.; Neumann, K.; Ludwig, B.; Gavalas, A.
10.1101/2023.09.06.556505 — developmental biology — Posted on 2023-10-10
3361 Transcriptional signatures associated with waterlogging stress responses and aerenchyma formation in barley root tissue
Sherwood, O. L.; Burke, R.; O'Rourke, J.; Whelan, C. V.; Downey, F.; Ryan, L.; McCabe, E. F.; Huang, Z.; Ng, C.; McCabe, P. F.; Kacprzyk, J.
10.1101/2023.10.06.561260 — plant biology — Posted on 2023-10-10
3362 The tidyomics ecosystem: Enhancing omic data analyses
Hutchison, W. J.; Keyes, T. J.; Crowell, H. L.; Soneson, C.; Mu, W.; Park, J.-E.; Davis, E. S.; Nahid, A. A.; Tang, M.; Yuan, V.; Axisa, P.-P.; Kitt, J. W.; Poon, C.-L.; Sato, N.; Kosmac, M.; Serizay, J.; Gottardo, R.; Morgan, M.; Lee, S.; Lawrence, M.; Hicks, S. C.; Nolan, G. P.; Davis, K. L.; Papenfuss, A. T.; Love, M. I.; Mangiola, S.
10.1101/2023.09.10.557072 — bioinformatics — Posted on 2023-10-10
3363 Songbirds avoid the oxidative stress costs of high blood glucose levels
Vagasi, C. I.; Vincze, O.; Adamkova, M.; Kauzalova, T.; Lendvai, A. Z.; Patras, L.; Penzes, J.; Pap, P. L.; Albrecht, T.; Tomasek, O.
10.1101/2023.05.09.539961 — evolutionary biology — Posted on 2023-10-10
3365 Alternative splicing induced by bacterial pore-forming toxins sharpens CIRBP-mediated cell response to Listeria infection
Corre, M.; Boehm, V.; Besic, V.; Kurowska, A.; Viry, A.; Mohammad, A.; Senamaud-Beaufort, C.; Thomas-Chollier, M.; Lebreton, A.
10.1101/2023.01.18.524578 — molecular biology — Posted on 2023-10-10
3366 Whole blood transcriptional profiles and the pathogenesis of tuberculous meningitis
Hai, H. T.; Nhat, L. T. H.; Tram, T. T. B.; Nath, A. P.; Donovan, J.; Thu, N. T. A.; Thanh, D. V.; Bang, N. D.; Ha, D. T. M.; Phu, N. H.; Nghia, H. D. T.; Van, L. H.; Inouye, M.; Thwaites, G. E.; Thuong, N. T. T.
10.1101/2023.10.06.561265 — molecular biology — Posted on 2023-10-10
3368 Detecting and quantifying clonal selection in somatic stem cells
Korber, V.; Ansari-Pour, N.; Jakobsen, N. A.; Moore, R.; Claudino, N.; Metzner, M.; Horsch, F.; Usukhbayar, B.; Salazar, M. A.; Newman, S.; Kendrick, B. J.; Taylor, A. H.; Afinowi-Luitz, R.; Gundle, R.; Watkins, B.; Wheway, K.; Beazley, D.; Dakin, S. G.; Carr, A. J.; Vyas, P.; Hofer, T.
10.1101/2021.12.15.472780 — cancer biology — Posted on 2023-10-10
3370 Illuminating the mechanism and allosteric behavior of NanoLuc luciferase
Nemergut, M.; Pluskal, D.; Horackova, J.; Sustrova, T.; Tulis, J.; Baatallah, R.; Gagnot, G.; Novakova, V.; Sedlackova, K.; Majerova, M.; Marques, S. M.; Toul, M.; Damborsky, J.; Prokop, Z.; Bednar, D.; Janin, Y. L.; Marek, M.
10.1101/2022.12.05.519101 — biochemistry — Posted on 2023-10-10
3376 The neural basis of swap errors in working memory
Alleman, M.; Panichello, M.; Buschman, T. J.; Johnston, W. J.
10.1101/2023.10.09.561584 — neuroscience — Posted on 2023-10-10
3377 REM Sleep Measures and REM Vagal Activity Predict Extinction Recall in Trauma-Exposed Individuals
Yuksel, C.; Watford, L.; Muranaka, M.; Lax, H.; Mendelsohn, A. K.; Oliver, K. I.; Daffre, C.; Acosta, A.; Vidrin, A.; Martinez, U.; Lasko, N.; Pace-Schott, E. F.
10.1101/2023.09.28.560007 — neuroscience — Posted on 2023-10-10
3378 Role of Dynamin-Related Proteins 2 and SH3P2 in Clathrin-Mediated Endocytosis in Plants
Gnyliukh, N.; Johnson, A.; Nagel, M.-K.; Monzer, A.; Hlavata, A.; Isono, E.; Loose, M.; Friml, J.
10.1101/2023.10.09.561523 — plant biology — Posted on 2023-10-10
3384 Integrated single-cell multiome analysis reveals muscle fiber-type gene regulatory circuitry modulated by endurance exercise
Rubenstein, A. B.; Smith, G. R.; Zhang, Z.; Chen, X.; Chambers, T. L.; Ruf-Zamojski, F.; Mendelev, N.; Cheng, W. S.; Zamojski, M.; Amper, M. A. S.; Nair, V. D.; Marderstein, A. R.; Montgomery, S. B.; Troyanskaya, O. G.; Zaslavsky, E.; Trappe, T.; Trappe, S.; Sealfon, S. C.
10.1101/2023.09.26.558914 — genomics — Posted on 2023-10-10
3386 Diet and chemical defenses of the Sonoran Desert toads
Luccioni, M. D.; Wyman, J. T.; O'Connell, L. A.; Espinoza, E.
10.1101/2023.10.06.561297 — ecology — Posted on 2023-10-09
3387 The Atlantic Forest of South America: spatiotemporal dynamics of remaining vegetation and implications for conservation
Vancine, M. H.; Muylaert, R. L.; Niebuhr, B. B.; Oshima, J. E. d. F.; Tonetti, V.; Bernardo, R.; De Angelo, C.; Rosa, M. R.; Grohmann, C. H.; Ribeiro, M. C.
10.1101/2023.09.16.558076 — ecology — Posted on 2023-10-09
3388 An in vitro platform for quantifying cell cycle phase lengths in primary human intestinal stem cells
Cotton, M. J.; Ariel, P.; Chen, K.; Walcott, V. A.; Dixit, M.; Breau, K. A.; Hinesley, C. M.; Kedziora, K.; Tang, C. Y.; Zheng, A.; Magness, S. T.; Burclaff, J.
10.1101/2023.10.09.561410 — cell biology — Posted on 2023-10-10
3389 SERF2, an RNA G-quadruplex Binding Protein, promotes stress granule formation
Sahoo, B. R.; Deng, X.; Wong, E. L.; Clark, N.; Yang, H.; Subramanian, V.; Guzman, B. B.; Harris, S. E.; Dehury, B.; Miyashita, E.; Saito, H.; Dominguez, D.; Bardwell, J. C.
10.1101/2023.10.09.561572 — cell biology — Posted on 2023-10-10
3390 Dirus Complex Species Identification PCR (DiCSIP) improves identification of Anopheles dirus complex from Greater Mekong Subregion
Saeung, M.; Pengon, J.; Pethrak, C.; Thaiudomsap, S.; Lhaosudto, S.; Saeung, A.; Manguin, S.; Chareonviriyaphap, T.; Jupatanakul, N.
10.1101/2023.10.09.561471 — molecular biology — Posted on 2023-10-10
3393 A developmentally defined population of neurons in the lateral septum controls responses to aversive stimuli
Turrero Garcia, M.; Tran, D. N.; Peterson, R. E.; Stegmann, S. K.; Hanson, S. M.; Reid, C. M.; Xie, Y.; Vu, S.; Harwell, C. C.
10.1101/2023.09.24.559205 — neuroscience — Posted on 2023-10-09
3396 A combined lipidomic and proteomic profiling of Arabidopsis thaliana plasma membrane
Bahammou, D.; Recorbet, G.; Mamode Cassim, A.; Robert, F.; Balliau, T.; Van Delf, P.; Haddad, Y.; Mongrand, S.; Fouillen, L.; Simon-Plas, F.
10.1101/2023.05.14.540643 — plant biology — Posted on 2023-10-09
3397 Mechanisms of carbon dioxide detection in the earthworm Dendrobaena veneta.
Smith, E. J.; Ryan, J. L.; Lopresti, S. A.; Haghnazari, D. B.; Anderson, K. A.; Lipson, S. J.; Johnson, E. C.; Silver, W. L.; Saunders, C. J.
10.1101/2023.04.12.536649 — physiology — Posted on 2023-10-09
3399 Genetic, Clinical Underpinnings of Brain Change Along Two Neuroanatomical Dimensions of Clinically-defined Alzheimer's Disease
Wen, J.; Yang, Z.; Nasrallah, I.; Cui, Y.; Erus, G.; Srinivasan, D.; Abdulkadir, A.; Mamourian, E.; Skampardoni, I.; Hwang, G.; Singh, A.; Bergman, M.; Bao, J.; Varol, E.; Zhou, Z.; Boquet-Pujadas, A.; Chen, J.; Toga, A. W.; Saykin, A. J.; Hohman, T.; Thompson, P.; Villeneuve, S.; Gollub, R.; Sotiras, A.; Wittfeld, K.; Grabe, H.; Tosun, D.; Bilgel, M.; An, Y.; Marcus, D.; LaMontagne, P. J.; Heckbert, S.; Austin, T.; Launer, L.; Espeland, M.; Masters, C.; Maruff, P.; Fripp, J.; Johnson, S. C.; Morris, J.; Albert, M.; Bryan, R. N.; Resnick, S. M.; Ferrucci, L.; Fan, Y.; Mohamad, H.; Wolk, D.; Sh
10.1101/2022.09.16.508329 — bioengineering — Posted on 2023-10-09
3400 Genomic context sensitizes regulatory elements to genetic disruption
Ordonez, R.; Zhang, W.; Ellis, G.; Zhu, Y.; Ashe, H. J.; Ribeiro-dos-Santos, A. M.; Brosh, R.; Huang, E.; Hogan, M. S.; Boeke, J. D.; Maurano, M. T.
10.1101/2023.07.02.547201 — genomics — Posted on 2023-10-09
3401 eQTL mapping in fetal-like pancreatic progenitor cells reveals early developmental insights into diabetes risk
Nguyen, J. P.; Arthur, T. D.; Fujita, K.; Salgado, B. M.; Donovan, M. K. R.; Consortium, i.; Matsui, H.; Kim, J. H.; D'Antonio-Chronowska, A.; D'Antonio, M.; Frazer, K. A.
10.1101/2021.03.17.435846 — genomics — Posted on 2023-10-09
3405 Patterned embryonic invagination evolved in response to mechanical instability
Vellutini, B. C.; Cuenca, M. B.; Krishna, A.; Szałapak, A.; Modes, C. D.; Tomancak, P.
10.1101/2023.03.30.534554 — developmental biology — Posted on 2023-10-09
3406 The condensation of HP1-????/Swi6 imparts nuclear stiffness
Williams, J. F.; Surovtsev, I. V.; Schreiner, S. M.; Chen, Z.; Raiymbek, G.; Nguyen, H.; Hu, Y.; Biteen, J. S.; Mochrie, S.; Ragunathan, K.; King, M. C.
10.1101/2020.07.02.184127 — cell biology — Posted on 2023-10-09
3408 Whole blood transcriptional profiles and the pathogenesis of tuberculous meningitis
Hai, H. T.; Thanh Hoang Le, N.; Tram, T. T. B.; Nath, A. P.; Donovan, J.; Thu, N. T. A.; Thanh, D. V.; Bang, N. D.; Ha, D. T. M.; Phu, N. H.; Nghia, H. D.; Le Hong, V.; Inouye, M.; Thwaites, G. E.; Thuong, N. T.
10.1101/2023.10.06.561265 — molecular biology — Posted on 2023-10-09
3411 Odor representations from the two nostrils are temporally segregated in human piriform cortex
Dikecligil, G. N.; Yang, A. I.; Sanghani, N.; Lucas, T.; Chen, H. I.; Davis, K. A.; Gottfried, J. A.
10.1101/2023.02.14.528521 — neuroscience — Posted on 2023-10-09
3412 Nucleus Accumbens Local Circuit for Cue-Dependent Aversive Learning
Belilos, A.; Gray, C.; Sanders, C.; Black, D.; Mays, E.; Richie, C. T.; Sengupta, A.; Hake, H. S.; Francis, T. C.
10.1101/2023.02.06.527338 — neuroscience — Posted on 2023-10-09
3414 Shorter self-reported sleep duration in men is associated with worse virtual spatial navigation performance
Yavuz, E.; Lazar, A. S.; Gahnstrom, C. J.; Goodroe, S.; Coutrot, A.; Hornberger, M.; Spiers, H. J.
10.1101/2023.09.09.556942 — neuroscience — Posted on 2023-10-09
3416 Nitric Oxide controls shoot meristem activity via regulation of DNA methylation
Zeng, J.; Zhao, X.; Liang, Z.; Hidalgo, I.; Gebert, M.; Fan, P.; Wenzl, C.; Gornik, S. G.; Lohmann, J. U.
10.1101/2023.10.06.561157 — plant biology — Posted on 2023-10-09
3418 Surface crosslinking of virus-like particles increases resistance to proteases, low pH and mechanical stress for mucosal applications
Ali, A.; Ganguillet, S.; Turgay, Y.; Keys, T.; Causa, E.; Fradique, R.; Lutz-Bueno, V.; Chesnov, S.; Lin, C.-W.; Lentsch, V.; Kotar, J.; Cicuta, P.; Mezzenga, R.; Slack, E.; Radiom, M.
10.1101/2023.07.29.550271 — biophysics — Posted on 2023-10-09
3419 NanoNERF: A nanoscale NERF blaster replica made of DNA
Takiguchi, L. P.; Rober, M. B.; Olvera, J. G.; Wacker, A. L.; Fantasia, R. J.; Liu, B.; Shipley, W.; Tao, A.; Kosuri, P.
10.1101/2023.10.02.560388 — biophysics — Posted on 2023-10-09
3420 Label-free Identification of Protein Aggregates Using Deep Learning
Ibrahim, K. A.; Grussmayer, K. S.; Riguet, N.; Feletti, L.; Lashuel, H. A.; Radenovic, A.
10.1101/2023.04.21.537833 — bioengineering — Posted on 2023-10-09
3421 Delay of punishment highlights differential vulnerability to developing addiction-like behavior toward sweet food
Solinas, M.; Lardeux, V.; LeBlanc, P.-M.; Longueville, J.-E.; Thiriet, N.; Vandaele, Y.; Panlilio, L. V.; Jaafari, N.
10.1101/2023.10.09.559890 — animal behavior and cognition — Posted on 2023-10-09
3428 IpaA reveals distinct modes of vinculin activation during Shigella invasion and cell-matrix adhesion
Cocom-Chan, B.; Khakzad, H.; KONATE, M.; AGUILAR, D. I.; BELLO, C.; Valencia-Gallardo, C.; Zarrouk, Y.; FATTACCIOLI, J.; MAUVIEL, A.; JAVELAUD, D.; Tran Van Nhieu, G.
10.1101/2023.03.23.533139 — cell biology — Posted on 2023-10-09
3429 Human olfactory neuronal cells through nasal biopsy: molecular characterization and utility in brain science
Yang, K.; Ishizuka, K.; Lane, A. P.; Narita, Z.; Hayashida, A.; Lema, Y. Y.; Heffron, E.; Loudd, H.; Schumacher, M.; Kano, S.-i.; Tomoda, T.; Kamiya, A.; Ma, M.; Geman, D.; Younes, L.; Sawa, A.
10.1101/2022.09.23.509290 — molecular biology — Posted on 2023-10-09
3430 Collaborative Cross mice have diverse phenotypic responses to infection with Methicillin-resistant Staphylococcus aureus USA300
Nagarajan, A.; Scoggin, K.; Gupta, J.; Aminian, M.; Adams, L. G.; Kirby, M.; threadgill, D.; Andrews-Polymenis, H. L.
10.1101/2023.07.12.548741 — microbiology — Posted on 2023-10-09
3431 Genetic ablation of adhesion ligands averts rejection of allogeneic immune cells
Hammer, Q.; Perica, K.; van Ooijen, H.; Mbofung, R.; Momayyezi, P.; Varady, E.; Martin, K. E.; Pan, Y.; Jelcic, M.; Groff, B.; Abujarour, R.; Krokeide, S.; Lee, T.; Williams, A.; Goodridge, J. P.; Valamehr, B.; Onfelt, B.; Sadelain, M.; Malmberg, K.-J.
10.1101/2023.10.09.557143 — immunology — Posted on 2023-10-09
3432 Early and selective subcortical Tau pathology within the human Papez circuit
Sarkany, B.; David, C.; Hortobagyi, T.; Gombas, P.; Somogyi, P.; Acsady, L. J.; Viney, T. J.
10.1101/2023.06.05.543738 — neuroscience — Posted on 2023-10-09
3433 A single domain intrabody targeting the follicle-stimulating hormone receptor (FSHR) impacts FSH-induced G protein-dependent signalling
Raynaud, P.; Jugnarain, V.; Vaugrente, O.; Vallet, A.; Boulo, T.; Gauthier, C.; Inoue, A.; Sibille, N.; Gauthier, C.; Jean-Alphonse, F.; Reiter, E.; Crepieux, P.; Bruneau, G.
10.1101/2023.08.07.552286 — pharmacology and toxicology — Posted on 2023-10-09
3435 G6PD Maintains Redox Homeostasis and Biosynthesis in LKB1-Deficient KRAS-Driven Lung Cancer
Lan, T.; Arastu, S.; Wang, S.; Lam, J.; Wang, W.; Bhatt, V.; Lopes, E. C.; Hu, Z. S.; Sun, M.; Luo, X.; Ghergurovich, J. M.; Li, C.; Su, X.; Rabinowitz, J. D.; White, E.; Guo, J. Y.
10.1101/2023.10.06.561131 — cancer biology — Posted on 2023-10-09
3437 Engineered Active Zymogen of Microbial Transglutaminase
Ariyoshi, R.; Matsuzaki, T.; Sato, R.; Minamihata, K.; Hayashi, K.; Wakabayashi, R.; Goto, M.; Kamiya, N.
10.1101/2023.10.09.561484 — biochemistry — Posted on 2023-10-09
3441 Joint sequence & chromatin neural networks characterize the differential abilities of Forkhead transcription factors to engage inaccessible chromatin
Arora, S.; Yang, J.; Akiyama, T.; James, D.; Morrissey, A.; Blanda, T.; Badjatia, N.; Lai, W. K. M.; Ko, M. S. H.; Pugh, B. F.; Mahony, S.
10.1101/2023.10.06.561228 — genomics — Posted on 2023-10-09
3443 Unifying microorganisms and macrograzers in rocky shore ecological networks
Arboleda-Baena, C.; Pareja, C. B.; Poblete, J.; Berlow, E.; Sarmento, H.; Logares, R.; De la Iglesia, R.; Navarrete, S.
10.1101/2023.10.06.561312 — ecology — Posted on 2023-10-09
3446 Optical ice thickness measurement in the VitroJet for time-efficient single particle structure determination
Henderikx, R. J. M.; Shahzad, S.; Schotman, M. J. G.; Mann, D.; Heidler, T. V.; Leahy, E.; Ashtiani, D.; Jeurissen, R. J. M.; Peters, P. J.; Sachse, C.; Beulen, B. W. A. M. M.
10.1101/2023.10.09.561488 — molecular biology — Posted on 2023-10-09
3447 The Escherichia coli TolC efflux pump protein is immunogenic and elicits protective antibodies
Silva, T. O.; Costa, L. V. S.; Chagas do Nascimento, L.; Barbosa, L. S.; Fanticelli, J. G. C.; Rotilho, C.; Silva, L. S.; Abreu, J. d. S.; Rajsfus, B. F.; Bulla, A. C. S.; Carneiro, J.; Allonso, D.; Salgado, D.; da Silva, M. L.; Echevarria-Lima, J.; Moreira, L. d. O.; Olsen, P. C.
10.1101/2023.10.09.559948 — immunology — Posted on 2023-10-09
3448 Microglia facilitate and stabilize the response to general anesthesia
He, Y.; Liu, T.; He, Q.; Ke, W.; Li, X.; Du, J.; Deng, S.; Shu, Z.; Wu, J.; Yang, B.; Wang, Y.; Mao, Y.; Rao, Y.; Shu, Y.; Peng, B.
10.1101/2023.10.06.561235 — neuroscience — Posted on 2023-10-09
3450 Dopamine lesions alter the striatal encoding of single-limb gait
Yang, L.; Singla, D.; Wu, A. K.; Cross, K. A.; Masmanidis, S. C.
10.1101/2023.10.06.561216 — neuroscience — Posted on 2023-10-09
3453 Transposon-triggered epigenetic chromatin dynamics modulate EFR-related pathogen response
Mencia, R.; Arce, A. L.; Houriet, C.; Xian, W.; Contreras, A.; Shirsekar, G.; Weigel, D.; Manavella, P. A.
10.1101/2023.10.06.561201 — plant biology — Posted on 2023-10-09
3454 Zaxinone Synthase overexpression modulates rice physiology and metabolism, improving growth and productivity under normal and low phosphate supply
Ablazov, A.; Jamil, M.; Haider, I.; Wang, J. Y.; Melino, V.; Maghrebi, M.; Vigani, G.; Liew, K. X.; Lin, P.-Y.; Chen, G.-T.; Kuijer, H.; Berqdar, L.; Mazzarella, T.; Fiorilli, V.; Lanfranco, L.; Zheng, X.; Dai, N.-C.; Lai, M.-H.; Hsing, Y.-i.; Tester, M.; Blilou, I.; Al-Babili, S.
10.1101/2023.10.06.561198 — plant biology — Posted on 2023-10-09
3455 TMEM65 regulates NCLX-dependent mitochondrial calcium efflux
Garbincius, J. F.; Salik, O.; Cohen, H. M.; Choya-Foces, C.; Mangold, A. S.; Makhoul, A. D.; Schmidt, A. E.; Khalil, D. Y.; Doolittle, J. J.; Wilkinson, A. S.; Murray, E. K.; Lazaropoulos, M. P.; Hildebrand, A. N.; Tomar, D.; Elrod, J. W.
10.1101/2023.10.06.561062 — physiology — Posted on 2023-10-09
3463 Predicting prime editing efficiency across diverse edit types and chromatin contexts with machine learning
Mathis, N.; Allam, A.; Talas, A.; Benvenuto, E.; Schep, R.; Damodharan, T.; Balazs, Z.; Janjuha, S.; Schmidheini, L.; Böck, D.; van Steensel, B.; Krauthammer, M.; Schwank, G.
10.1101/2023.10.09.561414 — molecular biology — Posted on 2023-10-09
3464 Dirus Complex Species Identification PCR (DiCSIP) improves identification of Anopheles dirus complex from Greater Mekong Subregion
Saeung, M.; Pengon, J.; Pethrak, C.; Thaiudomsap, S.; Lhaosudto, S.; Saeung, A.; Manguin, S.; Chareonviriyaphap, T.; Jupatanakul, N.
10.1101/2023.10.09.561471 — molecular biology — Posted on 2023-10-09
3465 Whole blood transcriptional profiles and the pathogenesis of tuberculous meningitis
Hai, H. T.; Thanh Hoang Le, N.; Tram, T. T. B.; Nath, A. P.; Donovan, J.; Thu, N. T. A.; Thanh, D. V.; Bang, N. D.; Ha, D. T. M.; Phu, N. H.; Nghia, H. D.; Le Hong, V.; Inouye, M.; Thwaites, G. E.; Thuong, N. T.
10.1101/2023.10.06.561265 — molecular biology — Posted on 2023-10-09
3466 mRNA cap-binding protein eIF4E1 is a novel regulator of Toxoplasma gondii latency
Holmes, M. J.; Bastos, M. S.; Dey, V.; Severo, V.; Wek, R. C.; Sullivan, W. J.
10.1101/2023.10.09.561274 — microbiology — Posted on 2023-10-09
3468 Emergence of Acinetobacter baumannii International Clone 10 predominantly found in the Middle East
Karah, N.; Faille, N.; Grenier, F.; Fayad, A. A.; Higgins, P. G.; Al-Hassan, L.; Evans, B. A.; Poirel, L.; Bonnin, R.; Hammerum, A. M.; Hansen, F.; Rafei, R.; Hamze, M.; Didelot, X.; Castillo-Ramirez, S.; Levesque, S.; Rodrigue, S.; Uhlin, B. E.; Haraoui, L.-P.
10.1101/2023.10.09.561570 — microbiology — Posted on 2023-10-09
3471 CaMKIIalpha and CaMKIIbeta hub domains adopt distinct oligomeric states and stabilities
Ozden, C.; MacManus, S.; Samkutty, A.; Ocampo, A. T.; Garman, S. C.; Stratton, M. M.
10.1101/2023.10.09.561517 — biochemistry — Posted on 2023-10-09
3473 Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3 mediated IL-1β production in human macrophages and microglia
Liang, Z.; Damianou, A.; Vendrell, I.; Jenkins, E.; Lassen, F. H.; Washer, S. J.; Liu, G.; Yi, G.; Lou, H.; Cao, F.; Zheng, X.; Fernandes, R.; Dong, T.; Tate, E. W.; Daniel, E. D.; Kessler, B. M.
10.1101/2023.10.09.561576 — biochemistry — Posted on 2023-10-09
3475 A Suite of Designed Protein Cages Using Machine Learning Algorithms and Protein Fragment-Based Protocols
Meador, K.; Castells-Graells, R.; Aguirre, R.; Sawaya, M. R.; Arbing, M. A.; Sherman, T.; Senarathne, C.; Yeates, T. O.
10.1101/2023.10.09.561468 — biochemistry — Posted on 2023-10-09
3476 Generalized Biomolecular Modeling and Design with RoseTTAFold All-Atom
Krishna, R.; Wang, J.; Ahern, W.; Sturmfels, P.; Venkatesh, P.; Kalvet, I.; Lee, G. R.; Morey-Burrows, F. S.; Anishchenko, I.; Humphreys, I. R.; McHugh, R.; Vafeados, D.; Li, X.; Sutherland, G. A.; Hitchcock, A.; Hunter, C. N.; Baek, M.; DiMaio, F.; Baker, D.
10.1101/2023.10.09.561603 — biochemistry — Posted on 2023-10-09
3477 Structural Insights into the Interaction Between Adenovirus C5 Hexon and Human Lactoferrin
Dhillon, A.; Persson, B. D.; Volkov, A. N.; Sulzen, H.; Kadek, A.; Pompach, P.; Kereiche, S.; Lepsik, M.; Danskog, K.; Uetrecht, C.; Arnberg, N.; Zoll, S.
10.1101/2023.10.09.561496 — biochemistry — Posted on 2023-10-09
3478 A Cell Atlas of Thoracic Aortic Perivascular Adipose Tissue: a focus on mechanotransducers
Thompson, J. M.; Watts, S. W.; Terrian, L.; Contreras, G. A.; Rockwell, C.; Rendon, C. J.; Wabel, E.; Lockwood, L.; Bhattacharya, S.; Nault, R.
10.1101/2023.10.09.561581 — molecular biology — Posted on 2023-10-09
3479 The Rho GTPase Rac1 mediates exercise training adaptations
Raun, S. H.; Henriquez-Olguin, C.; Frank, E.; Knudsen, J. R.; Ali, M. S.; Andersen, N. R.; Moeller, L. L. V.; Davey, J.; Qian, H.; Coelho, A.; Carl, C. S.; Voldstedlund, C. T.; Kiens, B.; Holmdahl, R.; Gregorevic, P.; Jensen, T. E.; Richter, E. A.; Sylow, L.
10.1101/2023.10.08.561442 — molecular biology — Posted on 2023-10-09
3480 Cell-type-specific characterization of miRNA gene dynamics in immune cell subpopulations during aging and atherosclerosis disease development at single-cell resolution
de Sande, A. H.; Turunen, T.; Bouvy-Liivrand, M.; Ord, T.; Palani, S.; Tundidor-Centeno, C.; Liljenback, H.; Virta, J.; Smolander, O.-P.; Sinkkonen, L.; Sauter, T.; Roivainen, A.; Lonnberg, T.; Kaikkonen, M. U.; Heinaniemi, M.
10.1101/2023.10.09.561173 — molecular biology — Posted on 2023-10-09
3482 The SARS-CoV-2 Spike is a virulence determinant and plays a major role on the attenuated phenotype of Omicron virus in a feline model of infection
Martins, M.; Nooruzzaman, M.; Cunningham, J. L.; Ye, C.; Caserta, L. C.; Jackson, N.; Martinez-Sobrido, L.; Fang, Y.; Diel, D. G.
10.1101/2023.10.09.561473 — microbiology — Posted on 2023-10-09
3483 In silico MS/MS prediction for peptidoglycan profiling uncovers novel anti-inflammatory peptidoglycan fragments of the gut microbiota
Kwan, J. M. C.; Liang, Y.; Ng, E. W. L.; Sviriaeva, E.; Li, C.; Zhao, Y.; Zhang, X.-L.; Liu, X.-W.; Wong, S. H.; Qiao, Y.
10.1101/2023.10.08.561446 — microbiology — Posted on 2023-10-09
3484 Discovery of Novel Replication Proteins for Large Plasmids in Cyanobacteria and Their Potential Applications in Genetic Engineering
Ohdate, K.; Sakata, M.; Maeda, K.; Sakamaki, Y.; Nimura-Matsune, K.; Ohbayashi, R.; Hess, W. R.; Watanabe, S.
10.1101/2023.10.09.561360 — microbiology — Posted on 2023-10-09
3486 LETHAL COVID-19 ASSOCIATES WITH RAAS-INDUCED INFLAMMATION FOR MULTIPLE ORGAN DAMAGE INCLUDING MEDIASTINAL LYMPH NODES
Guarnieri, J. W.; Topper, M.; Beigel, K.; Haltoom, J. A.; Chadburn, A.; Frere, J.; An, J.; Cope, H.; Borczuk, A.; Sinha, S.; Lim, C.; Kim, J.; Park, J.; Meydan, C.; Foox, J.; Mozsary, C.; Bram, Y.; Richard, S.; Epsi, N.; Agan, B.; Chenoweth, J.; Simons, M.; Tribble, D.; Burgess, T.; Dalgard, C. L.; Heise, M. T.; Moorman, N.; Baxter, V.; Madden, E. A.; Taft-Benz, S.; Anderson, E.; Sanders, W. A.; Dickmander, R. J.; Widjaja, G. A.; Janssen, K.; Lie, T.; Murdock, D. G.; Angelin, A.; Albrecht, Y. E. S.; Olali, A.; Dybas, J. M.; Priebe, W.; Emmett, M. R.; Best, S.; Johnson, M. K.; Trovao, N. S.; Cl
10.1101/2023.10.08.561395 — immunology — Posted on 2023-10-09
3489 Biomolecular condensates form spatially inhomogeneous network fluids
Dar, F.; Cohen, S. R.; Mitrea, D. M.; Phillips, A. H.; Nagy, G.; Leite, W. C.; Stanley, C. B.; Choi, J.-M.; Kriwacki, R. W.; Pappu, R. V.
10.1101/2023.10.07.561338 — biophysics — Posted on 2023-10-09
3490 PAX6 protein in neuromasts of the lateral line system of salamanders (Eurycea)
Dobbins, B. A.; Tovar, R. U.; Oddo, B. J.; Devitt, T. J.; Hillis, D. M.; Garcia, D. M.
10.1101/2023.10.08.561443 — cell biology — Posted on 2023-10-09
3491 Characterising phagocytes and measuring phagocytosis from live Galleria mellonella larvae
Campbell, J. S.; Bebes, A.; Pradhan, A.; Yuecel, R.; Brown, A. J. P.; Wakefield, J. G.
10.1101/2023.10.09.558207 — cell biology — Posted on 2023-10-09
3492 Vinculin Antagonizes Branched Actin in Controlling Membrane Protrusion, Cell Migration and Cell Cycle Progression
James, J.; Fokin, A. I.; Guschin, D. Y.; Wang, H.; Polesskaya, A.; Rubtsova, S. N.; Le Clainche, C.; Silberzan, P.; Gautreau, A. M.; Romero, S.
10.1101/2023.10.09.561480 — cell biology — Posted on 2023-10-09
3494 The hepcidin-ferroportin axis influences mitochondrial function, proliferation, and migration in pulmonary artery endothelial and smooth muscle cells
Issitt, T.; Toe, Q.; Pedersen, S. L.; Shackshaft, T.; Ghazaly, M. M.; West, L.; Arnold, N. D.; Mahomed, A.; Kagugube, G. W.; Ramakrishnan, L.; Lawrie, A.; Wort, J. S.; Quinlan, G. J.
10.1101/2023.10.09.561497 — cell biology — Posted on 2023-10-09
3495 Host and viral determinants of airborne transmission of SARS-CoV-2 in the Syrian hamster
Port, J. R.; Morris, D. H.; Riopelle, J. C.; Yinda, C. K.; Avanzato, V. A.; Holbrook, M. G.; Bushmaker, T.; Schulz, J. E.; Saturday, T. A.; Barbian, K.; Russel, C. A.; Perry-Gottschalk, R.; Shaia, C. I.; Martens, C.; Lloyd-Smith, J. O.; Fischer, R. J.; Munster, V. J.
10.1101/2022.08.15.504010 — microbiology — Posted on 2023-10-09
3498 Square beams for optimal tiling in TEM
Chua, E. Y. D.; Alink, L. M.; Kopylov, M.; Eisenstein, F.; Johnston, J. D.; de Marco, A.
10.1101/2023.07.29.551095 — biophysics — Posted on 2023-10-09
3499 Atlas of Plasmodium falciparum intraerythrocytic development using expansion microscopy
Liffner, B.; Cepeda Diaz, A. K.; Blauwkamp, J.; Anaguano, D.; Frolich, S.; Muralidharan, V.; Wilson, D. W.; Dvorin, J.; Absalon, S.
10.1101/2023.03.22.533773 — cell biology — Posted on 2023-10-09
3500 Recruitment of apolipoprotein E facilitates Herpes simplex virus 1 attachment, entry, and release
Liu, L.; Thorsteinsson, K.; Bano, F.; Jayaweera, S. W.; Avinens, D.; Conca, D. V.; Pace, H.; Lövheim, H.; Olofsson, A.; Bally, M.
10.1101/2023.02.10.526562 — microbiology — Posted on 2023-10-09
3503 The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase
Bohl, V.; Hollmann, N. M.; Melzer, T.; Katikaridis, P.; Meins, L.; Simon, B.; Flemming, D.; Sinning, I.; Hennig, J.; Mogk, A.
10.1101/2023.10.08.561430 — biochemistry — Posted on 2023-10-09
3504 Allele biased transcription factor binding across human brain regions gives mechanistic insight into eQTLs
Moyers, B. A.; Loupe, J. M.; Felker, S. A.; Lawlor, J. M. J.; Anderson, A. G.; Rodriguez-Nunez, I.; Bunney, W. E.; Bunney, B. G.; Cartagena, P. M.; Sequeira, A.; Watson, S.; Akil, H.; Mendenhall, E. M.; Cooper, G. M.; Myers, R. M.
10.1101/2023.10.06.561245 — genomics — Posted on 2023-10-09
3505 Potential intrahospital dissemination of Pseudomonas aeruginosa carrying the blaIMP-1 gene within a Tn7-like transposon
Wang, Z.; Guo, X.; Zheng, L.; Zhu, L.; Yang, Y.; Guan, J.-y.; Chen, P.; Li, Q.; Lu, G.; Jing, J.; Sun, S.; Ji, X.; sun, y.; Jiang, B.; Guo, J.
10.1101/2023.10.06.561298 — genomics — Posted on 2023-10-09
3507 NEDD4-binding protein 1 suppresses HBV replication by degrading pgRNA
Kobayashi, N.; Suzuki, S.; Sakamoto, Y.; Suzuki, R.; Saito, T.; Izumi, T.; Noda, K.; Okuzaki, D.; Kanegae, Y.; Hayashi, S.; Tanaka, Y.; Matsuura, Y.; Takeuchi, O.; Tamura, T.; Taketomi, A.; Fukuhara, T.
10.1101/2023.10.06.561254 — microbiology — Posted on 2023-10-09
3509 Reply to: Commentary on Pang et al. (2023) Nature
Pang, J. C.; Aquino, K. M.; Oldehinkel, M.; Robinson, P. A.; Fulcher, B. D.; Breakspear, M.; Fornito, A.
10.1101/2023.10.06.560797 — neuroscience — Posted on 2023-10-09
3512 NeuroMotion: Open-source Simulator with Neuromechanical and Deep Network Models to Generate Surface EMG signals during Voluntary Movement
Ma, S.; Guerra, I. M.; Caillet, A. H.; Zhao, J.; Clarke, A. K.; Maksymenko, K.; Deslauriers-Gauthier, S.; Sheng, X.; Zhu, X.; Farina, D.
10.1101/2023.10.05.560588 — bioengineering — Posted on 2023-10-09
3513 Tailored mass spectral data exploration using the specXplore interactive dashboard
Mildau, K.; Ehlers, H.; Oesterle, I.; Pristner, M.; Warth, B.; Doppler, M.; Bueschl, C.; Zanghellini, J.; van der Hooft, J. J. J.
10.1101/2023.10.03.560677 — bioinformatics — Posted on 2023-10-09
3516 A globally synthesised and flagged bee occurrence dataset and cleaning workflow
Dorey, J. B.; Fischer, E. E.; Chesshire, P. R.; Nava-Bolanos, A.; OReilly, R. L.; Bossert, S.; Collins, S. M.; Lichtenberg, E. M.; Tucker, E. M.; Smith-Pardo, A.; Falcon-Brindis, A.; Guevara, D. A.; Ribeiro, B.; de Pedro, D.; Pickering, J.; James, K.-L.; Parys, K. A.; McCabe, L. M.; Rogan, M. S.; Minckley, R. L.; Velazco, S. J. E.; Griswold, T.; Zarrillo, T. A.; Jetz, W.; Sica, Y. V.; Orr, M. C.; Guzman, L. M.; Ascher, J. A.; Hughes, A. C.; Cobb, N. S.
10.1101/2023.06.30.547152 — ecology — Posted on 2023-10-09
3518 NeuroMechFly 2.0, a framework for simulating embodied sensorimotor control in adult Drosophila
Wang-Chen, S.; Stimpfling, V. A.; Ozdil, P. G.; Genoud, L.; Hurtak, F.; Ramdya, P.
10.1101/2023.09.18.556649 — neuroscience — Posted on 2023-10-09
3519 Small transcriptional differences among cell clones lead to distinct NF-κB dynamics
Kizilirmak, C.; Monteleone, E.; Garcia-Manteiga, J. M.; Brambilla, F.; Agresti, A.; Bianchi, M. E.; Zambrano, S.
10.1101/2021.12.07.471485 — systems biology — Posted on 2023-10-09
3520 MolEvolvR: A web-app for characterizing proteins using molecular evolution and phylogeny
Krol, J. D.; Burke, J. T.; Chen, S. Z.; Sosinski, L. M.; Alquaddoomi, F. S.; Brenner, E. P.; Wolfe, E. P.; Rubinetti, V. P.; Amolitos, S.; Reason, K. M.; Johnston, J. B.; Ravi, J.
10.1101/2022.02.18.461833 — genomics — Posted on 2023-10-08
3526 NanoNERF: A nanoscale NERF blaster replica made of DNA
Takiguchi, L. P.; Rober, M. B.; Olvera, J. G.; Wacker, A. L.; Fantasia, R. J.; Liu, B.; Shipley, W.; Tao, A.; Kosuri, P.
10.1101/2023.10.02.560388 — biophysics — Posted on 2023-10-08
3528 Inclusive living subcellular sequencing rendering physical physiological and human pathological features in osteoimmune diversity
Okada, H.; Terui, Y.; Omata, Y.; Terashima, A.; Seki, M.; Tani, S.; Kanazawa, S.; Hosonuma, M.; Miyahara, J.; Makabe, K.; Onodera, S.; Yano, F.; Kajiya, H.; Gori, F.; Saito, T.; Suzuki, Y.; Okabe, K.; Baron, R.; Chung, U.-i.; Tanaka, S.; Hojo, H.
10.1101/2022.09.05.506360 — genomics — Posted on 2023-10-08
3529 Seed functional ecology in Brazilian rock outcrop vegetation: an integrative synthesis
Ordonez-Parra, C. A.; Medeiros, N. F.; Dayrell, R. L. C.; Le Stradic, S.; Negreiros, D.; Cornelissen, T.; Silveira, F. A. O.
10.1101/2023.03.21.533674 — ecology — Posted on 2023-10-08
3530 Integrator-mediated clustering of poised RNA polymerase II synchronizes histone transcription
Lu, F.; Park, B. J.; Fujiwara, R.; Wilusz, J. E.; Gilmour, D. S.; Lehmann, R.; Lionnet, T.
10.1101/2023.10.07.561364 — genetics — Posted on 2023-10-08
3534 Proteome birthdating reveals age-selectivity of protein ubiquitination
Meadow, M. E.; Broas, S.; Hoare, M.; Alimohammadi, F.; Welle, K. A.; Swovick, K.; Hryhorenko, J. R.; Martinez, J. C.; Biashad, S. A.; Seluanov, A.; Gorbunova, V.; Buchwalter, A.; Ghaemmaghami, S.
10.1101/2023.10.08.561433 — biochemistry — Posted on 2023-10-08
3535 Functional coherence of the Xist and RSX protein interactomes: X chromosome inactivation marsupials
McIntyre, K. L.; Waters, S.; Zhong, L.; Hart-Smith, G.; Raftery, M.; Graves, J. A. M.; Waters, P. D.
10.1101/2023.10.08.560959 — genetics — Posted on 2023-10-08
3539 Diversity and adaptability of RNA viruses in rice planthopper, Laodelphax striatellus
Mao, Q.-Z.; Ye, Z.-X.; Yuan, J.-N.; Ning, C.; Chen, M.-N.; Qi, Y.-H.; Zhang, Y.; Li, T.; He, Y.-J.; Lu, G.; Huang, H.-J.; Zhang, C.-X.; Chen, J.-P.; Li, J.-M.
10.1101/2023.10.08.561400 — microbiology — Posted on 2023-10-08
3542 SmartEM: machine-learning guided electron microscopy
Meirovitch, Y.; Park, C. F.; Mi, L.; Potocek, P.; Sawmya, S.; Li, Y.; Wu, Y.; Schalek, R.; Pfister, H.; Schoenmakers, R.; Peemen, M.; Lichtman, J. W.; Samuel, A.; Shavit, N.
10.1101/2023.10.05.561103 — neuroscience — Posted on 2023-10-08
3543 Differential encoding of odor and place in mouse piriform and entorhinal cortex
Mena, W.; Baker, K.; Rubin, A.; Kohli, S.; Yoo, Y.; Ziv, Y.; Razaei-Mazinani, C.; Fleischmann, A.
10.1101/2023.10.05.561119 — neuroscience — Posted on 2023-10-08
3546 METTL3/MYCN cooperation drives m6A modification during trunk neural crest differentiation and represents a therapeutic vulnerability in MYCN-amplified neuroblastoma
Thombare, K.; Vaid, R.; Mendez, A.; Pucci, P.; Burgos-Panadero, R.; Ayyalusamy, R.; Rehan, A. A.; Bartenhagen, C.; Fischer, M.; Turner, S. D.; Mondal, T.
10.1101/2023.10.06.561194 — cancer biology — Posted on 2023-10-08
3548 Engineered blue-shifted melanopsins for subcellular optogenetics
Wijayaratna, D.; Sacchetta, F.; Pedraza Gonzalez, L.; Fanelli, F.; Sugihara, T.; Koyanagi, M.; Piyawardana, S.; Ghotra, K.; Thotamune, W.; Terakita, A.; Olivucci, M.; Karunarathne, A.
10.1101/2023.10.07.561352 — biochemistry — Posted on 2023-10-08
3550 Deep mutational scanning of CYP2C19 reveals a substrate specificity-abundance tradeoff
Boyle, G. E.; Sitko, K.; Galloway, J. G.; Haddox, H. K.; Bianchi, A. H.; Dixon, A.; Thomson, R. E. S.; Garge, R. K.; Rettie, A. E.; Rubin, A. F.; Geck, R. C.; Gillam, E. M. J.; DeWitt, W. S.; Matsen, F. A.; Fowler, D. M.
10.1101/2023.10.06.561250 — genetics — Posted on 2023-10-08
3552 A conserved N-terminal motif of CUL3 mediates assembly and licenses E3 ligase activation of CRL3KLHL22
Yin, Y.; Wang, W.; Liang, L.; Dai, Z.; Zuo, P.; Yu, S.; Lv, Y.; Ding, D.; Chen, H.; Jin, Y.; Mao, Y.
10.1101/2023.10.07.561329 — molecular biology — Posted on 2023-10-08
3553 Nitrosative stress under microaerobic conditions triggers inositol metabolism in Pseudomonas extremaustralis
Venero, E. C. S.; Giambartolomei, L.; Sosa, E.; Fernandez do Porto, D.; Lopez, N. I.; Tribelli, P. M.
10.1101/2023.10.08.561431 — microbiology — Posted on 2023-10-08
3554 An axonemal intron splicing program sustains Plasmodium male development
Guan, J.; Wu, P.; Mo, X.; Zhang, X.; Liang, W.; Zhang, X.; Jiang, L.; Li, J.; Cui, H.; Yuan, J.
10.1101/2023.10.07.561333 — microbiology — Posted on 2023-10-08
3555 Evolution of genotypic and phenotypic diversity in multispecies biofilms
Amador, C. I.; Moskovitz, S. Z.; Maccario, L.; Herschend, J.; Kramer, I. S.; Jeckel, H.; Cooper, V. S.; Drescher, K.; Neu, T. R.; Burmolle, M.; Roder, H. L.
10.1101/2023.10.08.561388 — microbiology — Posted on 2023-10-08
3561 Cellular Calcium Activity at Depth Predicted from Surface Potential Recordings using Ultra-high Density Transparent Graphene Arrays
Ramezani, M.; Kim, J.-H.; Liu, X.; Ren, C.; Alothman, A.; De- Eknamkul, C.; Wilson, M.; Cubukcu, E.; Gilja, V.; Komiyama, T.; Kuzum, D.
10.1101/2023.10.05.561133 — neuroscience — Posted on 2023-10-08
3562 Collagen Tubular Airway-on-Chip for Extended Epithelial Culture andInvestigation of Ventilation Dynamics
Gao, W.; Kanagarajah, K. R.; Graham, E.; Soon, K.; Veres, T.; Moraes, T. J.; Bear, C. E.; Veldhuizen, R.; Wong, A. P.; Guenther, A.
10.1101/2023.10.05.561125 — bioengineering — Posted on 2023-10-08
3563 Hybrid hydrogel-extracellular matrix scaffolds identify distinct ligand and mechanical signatures in cardiac aging
Sun, A. R.; Ramli, M. F. H.; Shen, X.; Chen, D.; Foo, R. S.; Zhu, J.; Ackers-Johnson, M.; Young, J. L.
10.1101/2023.10.06.561048 — bioengineering — Posted on 2023-10-08
3566 Neutral competition explains the clonal composition of neural organoids
Pflug, F. G.; Haendeler, S.; Esk, C.; Lindenhofer, D.; Knoblich, J. A.; von Haeseler, A.
10.1101/2021.10.06.463206 — systems biology — Posted on 2023-10-08
3567 Co-transcriptional production of programmable RNA condensates and synthetic organelles
Fabrini, G.; Nuccio, S. P.; Stewart, J. M.; Lin, S.; Tang, A.; Rothemund, P. W. K.; Franco, E.; Di Antonio, M.; Di Michele, L.
10.1101/2023.10.06.561174 — synthetic biology — Posted on 2023-10-08
3568 On the reproductive mechanism of Gram-negative protoplasts
Kanaparthi, D.; Lampe, M.; Krohn, J. H.; Zhu, B.; Klingl, A.; Lueders, T.
10.1101/2021.11.25.470037 — biophysics — Posted on 2023-10-08
3579 Amniotic Fluid Organoids As Personalized Tools For Real-Time Modeling Of The Developing Fetus
Babosova, O.; Weisz, B.; Rabinowitz, G.; Avnet, H.; Shani, H.; Schwartz, A.; Batsry, L.; Pardo, N.; Elkan, T.; Stockheim, D.; Jubany, T.; Frank, D.; Barshack, I.; Dotan, Z.; Levin-Klein, R.; Beckerman, P.; Pleniceanu, O.
10.1101/2023.10.05.561078 — developmental biology — Posted on 2023-10-07
3580 The common TMEM173 HAQ, AQ alleles rescue CD4 T cell death, restore T-regs, and prevent SAVI (N153S) inflammatory disease in mice
Aybar-Torries, A. a.; saldarriaga, L. A.; Pham, A. T.; Emtiazjoo, A. M.; Sharma, A. K.; Bryant, A. J.; jin, l.
10.1101/2023.10.05.561109 — immunology — Posted on 2023-10-07
3583 A topographical atlas of alpha-Synuclein dosage and cell-type expression in the mouse brain and periphery
Geertsma, H. M.; Fisk, Z. A.; Sauline, L.; Prigent, A.; Kurgat, K.; Callaghan, S. M.; aSCENT PD Consortium, ; Henderson, M.; Rousseaux, M. W. C.
10.1101/2023.10.05.559770 — neuroscience — Posted on 2023-10-07
3585 Serum Lipidome Profiling Reveals a Distinct Signature of Ovarian Cancer in Korean Women
Sah, S.; Bifarin, O. O.; Moore, S. G.; Gaul, D. A.; Chung, H.; Cho, H.; Cho, C.-H.; Kim, J.-H.; Kim, J.; Fernandez, F. O.
10.1101/2023.10.05.560751 — cancer biology — Posted on 2023-10-07
3587 Targeted protein degradation via intramolecular bivalent glues
Hsia, O.; Hinterndorfer, M.; Cowan, A. D.; Iso, K.; Ishida, T.; Sundaramoorthy, R.; Nakasone, M. A.; Imrichova, H.; Schatz, C.; Rukavina, A.; Husnjak, K.; Wegner, M.; Correa-Saez, A.; Craigon, C.; Casement, R.; Maniaci, C.; Testa, A.; Kaulich, M.; Dikic, I.; Winter, G. E.; Ciulli, A.
10.1101/2023.02.14.528511 — biochemistry — Posted on 2023-10-07
3588 When paleontology meets genomics: complete mitochondrial genomes of two saber-toothed cats' species (Felidae: Machairodontinae)
Rodrigues-Oliveira, I. H.; Batista da Silva, I.; Rodrigues Rocha, R.; Silva Soares, R. A.; Menegidio, F. B.; Garcia, C.; Pasa, R.; Kavalco, K. F.
10.1101/2023.09.14.557696 — genomics — Posted on 2023-10-07
3589 Mimetic butterfly wings through mimetic butterfly eyes: Evidence that brightness vision helps Adelpha fessonia identify potential mates
Dang, A.; Bernard, G. D.; Yuan, F.; Macias-Munoz, A.; Hill, R. I.; Lawrence, J. P.; Olguin, A. R. G.; Luis-Martinez, A.; Mullen, S. P.; Llorente-Bousquets, J.; Briscoe, A. D.
10.1101/2023.10.05.561098 — evolutionary biology — Posted on 2023-10-07
3597 Heparan-6-O-endosulfatase 2 promotes invasiveness of head and neck squamous carcinoma cell lines in co-cultures with cancer associated fibroblasts
Mukherjee, P.; Zhou, X.; Benicky, J.; Panigrahi, A.; Aljuhani, R.; Liu, J.; Ailles, L.; Pomin, V. H.; Wang, Z.; Goldman, R.
10.1101/2023.10.05.561077 — cancer biology — Posted on 2023-10-07
3603 Transcriptional profiling of peripheral blood mononuclear cells identifies inflammatory phenotypes in ataxia telangiectasia
Michki, N. S.; Singer, B. D.; Perez, J. V.; Thomas, A. J.; Natale, V.; Helmin, K. A.; Wright, J.; Cheng, L.; Young, L. R.; Lederman, H. M.; McGrath-Morrow, S. A.
10.1101/2023.10.05.561081 — immunology — Posted on 2023-10-07
3604 Collaborative Augmented Reconstruction for Scaled Production of 3D Neuron Morphology in Mouse and Human Brains
Zhang, L.; Huang, L.; Yuan, Z.; Hang, Y.; Zeng, Y.; Li, K.; Wang, L.; Zeng, H.; Chen, X.; Zhang, H.; Xi, J.; Chen, D.; Gao, Z.; Le, L.; Chen, J.; Ye, W.; Liu, L.; Wang, Y.; Peng, H.
10.1101/2023.10.06.561172 — neuroscience — Posted on 2023-10-07
3605 Early nuclear phenotypes and reactive transformation in human iPSC-derived astrocytes from ALS patients with SOD1 mutations
Soubannier, V.; Chaineau, M.; Gursu, L.; Lepine, S.; Kalaydjian, D.; Haghi, G.; Rouleau, G.; Durcan, T.; Stifani, S.
10.1101/2023.10.05.561079 — neuroscience — Posted on 2023-10-07
3608 Biomarker discovery in progressive supranuclear palsy from human cerebrospinal fluid using mass spectrometry-based proteomics
Jang, Y.; Oh, S.; Hall, A. J.; Zhang, Z.; Tropea, T. F.; Chen-Plotkin, A.; Rosenthal, L. S.; Dawson, T. M.; Na, C.-H.; Pantelyat, A. Y.
10.1101/2023.10.05.561075 — systems biology — Posted on 2023-10-07
3610 A supernumerary synthetic chromosome in Komagataella phaffii as a repository for extraneous genetic material
Abramczyk, D.; Sanchez-Olmos, M. d. C.; Ramirez Rojas, A. A.; Schindler, D.; Robertson, D.; McColm, S.; Marston, A.; Barlow, P.
10.1101/2023.10.05.561004 — bioengineering — Posted on 2023-10-07
3613 Integrative analysis reveals a conserved role for the amyloid precursor protein in proteostasis during aging
Nithianandam, V.; Bukhari, H.; Leventhal, M. J.; Battaglia, R. A.; Dong, X.; Fraenkel, E.; Feany, M. B.
10.1101/2023.10.06.560646 — neuroscience — Posted on 2023-10-07
3615 Rapid threat assessment in the Drosophila thermosensory system
Jouandet, G. C.; Alpert, M. H.; Simoes, J. M.; Suhendra, R.; Frank, D. D.; Levy, J. I.; Kath, W. L.; Para, A.; Kath, W. L.; Gallio, M.
10.1101/2023.10.05.560966 — neuroscience — Posted on 2023-10-07
3616 The Hierarchy of Psychedelic Effects: Three Systematic Reviews and Meta-Analyses
Shinozuka, K.; Jerotic, K.; Mediano, P. A. M.; Zhao, A. T.; Preller, K. H.; Carhart-Harris, R. L.; Kringelbach, M. L.
10.1101/2023.10.06.561183 — neuroscience — Posted on 2023-10-07
3620 A highly resolved multiplex network reveals the structural role of insects and plants in terrestrial food webs
Hale, K. R. S.; Curlis, J. D.; Auteri, G. G.; Bishop, S.; French, R. L. K.; Jones, L. E.; Mills, K. L.; Simons, M.; Scholtens, B. G.; Thompson, C.; Tourville, J.; Valdovinos, F. S.
10.1101/2023.10.05.560934 — ecology — Posted on 2023-10-07
3621 Predicting Suitable Habitats Of Critically Endangered Chinese Pangolin In Assam, India
Sarma, K.; C, M. K.; Boro, B. K.; Saikia, M. K.; Sarania, B.; Basumatary, H.; Saikia, B. P.; Saikia, P. K.
10.1101/2023.10.05.561022 — ecology — Posted on 2023-10-07
3623 Microglia shape hippocampal networks but are dispensable for pruning of synapses during development
Surala, M.; Soso-Zdravkovic, L.; Munro, D.; Rifat, A.; Ouk, K.; Vida, I.; Priller, J.; Madry, C.
10.1101/2023.10.05.560092 — neuroscience — Posted on 2023-10-07
3625 Decoding muscle-resident Schwann cell dynamics during neuromuscular junction remodeling
Guzman, S. D.; Abu-Mahfouz, A.; Davis, C. S.; Ruiz, L. P.; Macpherson, P. C.; Brooks, S. V.
10.1101/2023.10.06.561193 — neuroscience — Posted on 2023-10-07
3626 Sex-specific resilience of neocortex to food restriction
Padamsey, Z.; Katsanevaki, D.; Maeso, P.; Rizzi, M.; Osterweil, E. E.; Rochefort, N. L.
10.1101/2023.10.06.561185 — neuroscience — Posted on 2023-10-07
3629 Ectopic adipogenesis in response to injury and material implantation in an autoimmune mouse model
Ngo, T. B.; Josyula, A.; DeStefano, S.; Fertil, D.; Faust, M.; Lokwani, R.; Sadtler, K.
10.1101/2023.10.05.561105 — bioengineering — Posted on 2023-10-07
3630 Pervasive GxE interactions shape adaptive trajectories and the exploration of the phenotypic space in artificial selection experiments
Desbiez-Piat, A.; Ressayre, A.; MARCHADIER, E.; Noly, A.; Remoue, C.; Vitte, C.; Belcram, H.; Bourgais, A.; Galic, N.; Le Guilloux, M.; Tenaillon, M. I.; Dillmann, C.
10.1101/2023.01.13.523786 — evolutionary biology — Posted on 2023-10-07
3632 Navigating Pubertal Goldilocks: The Optimal Pace for Hierarchical Brain Organization
Szakacs, H. M.; Mutlu, M. C.; Balestrieri, G.; Gombos, F.; Braun, J.; Kringelbach, M. L.; Deco, G.; Kovacs, I.
10.1101/2023.08.30.555584 — neuroscience — Posted on 2023-10-07
3633 The Unique Cytoarchitecture and Wiring of the Human Default Mode Network
Paquola, C.; Garber, M.; Frässle, S.; Royer, J.; Tavakol, S.; Rodriguez-Cruces, R.; Cabalo, D. G.; Valk, S. L.; Eickhoff, S.; Margulies, D. S.; Evans, A. C.; Amunts, K.; Jefferies, E.; Smallwood, J.; Bernhardt, B.
10.1101/2021.11.22.469533 — neuroscience — Posted on 2023-10-07
3634 MocFormer: A Two-Stage Pre-training-Driven Transformer for Drug-Target Interactions Prediction
Zhang, Y.-L.; Wang, W.-T.; Guan, J.-H.; Jain, D. K.; Yang, H.-W.; Wang, T.-Y.; Roy, S. K.
10.1101/2023.09.13.557595 — bioinformatics — Posted on 2023-10-07
3635 MMPs and NETs are detrimental in human CNS-tuberculosis and MMP inhibition in a mouse model improves survival
Poh, X. Y.; Loh, F. K.; Bai, C.; Chong, H. T.; Teo, W. K.; Hong, J. M.; Miow, Q. H.; Thong, P. M.; Vilaysane, B.; Hu, T. H.; Chhabra, S.; Wang, Y.; Tiong, S. C.; Fong, S. M.; Kamihigashi, M.; Rajarethinam, R.; Looi, W. D.; Cheow, E. S. H.; Bonney, G. K.; Pakkiri, L. S.; Drum, C. L.; Peng, Y. F.; Lee, M.; Tan, C. L.; Ding, C. S. L.; Lim, T. C. C.; Yeo, T. W.; Tay, J. K.; Vallejo, A. F.; Ong, C. W. M.
10.1101/2023.10.05.561002 — pathology — Posted on 2023-10-07
3637 Modular RNA motifs for orthogonal phase separated compartments
Stewart, J. M.; Li, S.; Tang, A.; Klocke, M. A. K. A.; Gobry, M. V.; Fabrini, G.; Di Michele, L.; Rothemund, P. W. K.; Franco, E.
10.1101/2023.10.06.561123 — synthetic biology — Posted on 2023-10-06
3639 Sleep deprivation detected by voice analysis
Thoret, E.; Andrillon, T.; Gauriau, C.; Leger, D.; Pressnitzer, D.
10.1101/2022.11.17.516913 — neuroscience — Posted on 2023-10-07
3640 A green alternative to fragrant agarwood sesquiterpenoid production
Gutierrez, S.; Overmans, S.; Wellman, G. B.; Samaras, V. G.; Oviedo, C.; Gede, M.; Szekely, G.; Lauersen, K. J.
10.1101/2023.10.06.561217 — synthetic biology — Posted on 2023-10-07
3642 Suppression of the Integrated Stress Response in Islet β Cells Decreases Risk of Autoimmune Diabetes
Muralidharan, C.; Huang, F.; Enriquez, J. R.; Wang, J. E.; Nelson, J. B.; Nargis, T.; May, S. C.; Chakraborty, A.; Figatner, K. T.; Navitskaya, S.; Anderson, C. M.; Calvo, V.; Surguladze, D.; Mulvihill, M. J.; Yi, X.; Sarkar, S.; Oakes, S. A.; Webb-Robertson, B.-J. M.; Eizirik, D. L.; Nakayasu, E. S.; Stokes, M. E.; Tersey, S. A.; Mirmira, R. G.
10.1101/2023.10.06.561126 — cell biology — Posted on 2023-10-06
3643 A Novel Interaction Between Aquaporin 1 and Caspase-3 in Pulmonary Arterial Smooth Muscle Cells
Niedermeyer, S.; Yun, X.; Trujillo, M.; Andrade, M.; Kolb, T.; Suresh, K.; Damarla, M.; Shimoda, L.
10.1101/2023.10.05.561144 — cell biology — Posted on 2023-10-06
3644 A primordial TFEB-TGFβ signaling axis systemically regulates diapause and stem cell longevity
Nonninger, T. J.; Mak, J.; Gerisch, B.; Ramponi, V.; Kawamura, K.; Schilling, K.; Latza, C.; Koelschbach, J.; Ripa, R.; Serrano, M.; Antebi, A.
10.1101/2023.10.06.561181 — cell biology — Posted on 2023-10-06
3648 N-cadherin mechanosensing in ovarian follicles controls oocyte maturation and ovulation
Emery, A.; Blaschuk, O. W.; Dinh, D. T.; McPhee, T.; Becker, R.; Abell, A. D.; Mrozik, K. M.; Zannettino, A. C.; Robker, R.; Russell, D. L.
10.1101/2023.10.06.561232 — cell biology — Posted on 2023-10-06
3649 Linear ubiquitination at damaged lysosomes induces local NF-κB activation and controls cell survival
Zein, L.; Dietrich, M.; Balta, D.; Bader, V.; Scheuer, C.; Zellner, S.; Weinelt, N.; Vandrey, J.; Mari, M. C.; Behrends, C.; Zunke, F.; Winklhofer, K. F.; van Wijk, S. J. L.
10.1101/2023.10.06.560832 — cell biology — Posted on 2023-10-06
3650 Cadherin-dependent adhesion is required for muscle stem cell niche anchorage and maintenance
Hung, M.; Lo, H.-F.; Beckmann, A. G.; Demircioglu, D.; Damle, G.; Hasson, D.; Radice, G. L.; Krauss, R. S.
10.1101/2023.10.05.561107 — cell biology — Posted on 2023-10-06
3652 High-resolution mapping of Ryd4Hb, a major resistance gene to Barley yellow dwarf virus from Hordeum bulbosum
Pidon, H.; Ruge-Wehling, B.; Will, T.; Habekuss, A.; Wendler, N.; Oldach, K.; Maasberg-Prelle, A.; Korzun, V.; Stein, N.
10.1101/2023.09.19.558385 — plant biology — Posted on 2023-10-06
3654 Nphos: Database and Predictor of Protein N-phosphorylation
Ming-Xiao, Z.; Ruo-Fan, D.; Qiang, C.; Junhua, M.; Fulai, L.; Songsen, F.; Biling, H.; Yan, L.; Ji, Z.-L.; Yufen, Z.
10.1101/2023.10.03.559246 — bioinformatics — Posted on 2023-10-06
3655 A comparative approach for selecting orthologous candidate genes underlying signal in genome-wide association studies across multiple species
Whitt, L.; Mahood, E. H.; Ziegler, G.; Luebbert, C.; Gillman, J. D.; Norton, G. J.; Price, A. H.; Salt, D. E.; Dilkes, B.; Baxter, I.
10.1101/2023.10.05.561051 — genetics — Posted on 2023-10-06
3658 Psychosocial experiences are associated with human brain mitochondrial biology
Trumpff, C.; Monzel, A.; Sandi, C.; Menon, V.; Klein, H.-U.; Fujita, M.; Lee, A. J.; Petyuk, V. A.; Hurst, C.; Duong, D. A.; Seyfried, N.; Wingo, A.; Wingo, T. S.; Wang, Y.; Thambisetty, M.; Ferrucci, L.; Bennett, D. A.; De Jager, P.; Picard, M.
10.1101/2023.10.06.559575 — cell biology — Posted on 2023-10-06
3659 IL-15 complex-induced IL-10 enhances Plasmodium-specific CD4+ Tfh differentiation and antibody production
Bravo, M.; Dileepan, T.; Dolan, M.; Hildebrand, J.; Wolford, J.; Hamilton, S. E.; Frosch, A. E.; Burrack, K. S.
10.1101/2023.10.06.561264 — immunology — Posted on 2023-10-06
3661 ATF2 phosphorylation is essential for neuronal apoptosis and links the DLK/LZK kinase cascade to JUN upregulation
Gomez Deza, J.; Nebiyou, M.; Alkaslasi, M. R.; El Touny, L. H.; Slavutsky, A. L.; Ashby, N.; Cheng, K.; Le Pichon, C. E.
10.1101/2023.09.27.559856 — neuroscience — Posted on 2023-10-06
3662 Cue-specific neuronal ensembles span intermittent rate coding of working memory
Panichello, M. F.; Jonikaitis, D.; Oh, J.; Zhu, S.; Trepka, E. B.; Moore, T.
10.1101/2023.10.06.561121 — neuroscience — Posted on 2023-10-06
3663 Co-transcriptional production of programmable RNA condensates and synthetic organelles
Fabrini, G.; Nuccio, S. P.; Stewart, J. M.; Lin, S.; Tang, A.; Rothemund, P. W. K.; Franco, E.; Di Antonio, M.; Di Michele, L.
10.1101/2023.10.06.561174 — synthetic biology — Posted on 2023-10-06
3666 Phased assembly of neo-sex chromosomes reveals extensive Y degeneration and rapid genome evolution in Rumex hastatulus
Sacchi, B. M.; Humphries, Z.; Kruzlicova, J.; Bodlakova, M.; Pyne, C.; Choudhury, B.; Gong, Y.; Bacovsky, V.; Hobza, R.; Barrett, S. C. H.; Wright, S. I.
10.1101/2023.09.26.559509 — evolutionary biology — Posted on 2023-10-06
3668 ACD15, ACD21, and SLN regulate accumulation and mobility of MBD6 to silence genes and transposable elements.
Boone, B. A.; Ichino, L.; Wang, S.; Gardiner, J.; Yun, J.; Jami-Alahmadi, Y.; Sha, J.; Mendoza, C. P.; Steelman, B. J.; Aardenne, A. v.; Kira-Lucas, S.; Trentchev, I.; Wohlschlegel, J.; Jacobsen, S. E.
10.1101/2023.08.23.554494 — cell biology — Posted on 2023-10-06
3669 Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp
Neininger-Castro, A. C.; Hayes, J. B.; Sanchez, Z. C.; Taneja, N.; Fenix, A. M.; Moparthi, S.; Vassilopoulos, S.; Burnette, D. T.
10.1101/2023.01.11.523681 — cell biology — Posted on 2023-10-06
3671 Ventrointermediate thalamic stimulation improves motor learning in humans
Voegtle, A.; Terzic, L.; Farahat, A.; Hartong, N.; Galazky, I.; Hinrichs, H.; Nasuto, S. J.; de Oliveira Andrade, A.; Knight, R. T.; Ivry, R. B.; Voges, J.; Deliano, M.; Buentjen, L.; Sweeney-Reed, C. M.
10.1101/2023.09.19.558378 — neuroscience — Posted on 2023-10-06
3672 Exploratory Correlation of The Human Structural Connectome with Non-MRI Variables in Alzheimer's Disease
Aganj, I.; Mora, J.; Frau-Pascual, A.; Fischl, B. R.; Alzheimer's Disease Neuroimaging Initiative,
10.1101/2023.06.30.547308 — neuroscience — Posted on 2023-10-06
3673 Brain Metabolic Network Covariance and Aging in a Mouse Model of Alzheimer's Disease
Chumin, E. J.; Burton, C.; Silvola, R.; Miner, E. W.; Persohn, S. C.; Veronese, M.; Territo, P. R.
10.1101/2023.06.21.545918 — neuroscience — Posted on 2023-10-06
3674 Local contribution to the somatosensory evoked potentials in rat's thalamus
Sredniawa, W.; Borzymowska, Z.; Kondrakiewicz, K.; Jurgielewicz, P.; Mindur, B.; Wojcik, D. K.; Kublik, E.
10.1101/2023.05.25.541803 — neuroscience — Posted on 2023-10-06
3675 Induction of antiviral Interferon-Stimulated Genes (ISGs) by neuronal STING promotes the resolution of pain
Defaye, M.; Bradaia, A.; Abdullah, N.; Agosti, F.; Iftinca, M.; Soubeyre, V.; Svendsen, K.; Gill, G.; Cumenal, M.; Gheziel, N.; Martin, J.; Basso, L.; Bourinet, E.; Chiu, I.; Altier, C.
10.1101/2023.08.04.551993 — neuroscience — Posted on 2023-10-06
3679 Developing best practices for genotyping-by-sequencing analysis in the construction of linkage maps
Taniguti, C. H.; Taniguti, L. M.; Amadeu, R. R.; Lau, J.; Gesteira, G. d. S.; Oliveira, T. d. P.; Ferreira, G. C.; Pereira, G. d. S.; Byrne, D.; Mollinari, M.; Riera-Lizarazu, O.; Garcia, A. A. F.
10.1101/2022.11.24.517847 — bioinformatics — Posted on 2023-10-06
3685 Deciphering Cell-types and Gene Signatures Associated with Disease Activity in Rheumatoid Arthritis using Single Cell RNA-sequencing
Binvignat, M.; Miao, B.; Wibrand, C.; Yang, M.; Rychkov, D.; Flynn, E.; Nititham, J.; Tamaki, W.; Khan, U.; Carvidi, A.; Krueger, M.; Niemi, E.; Sun, Y.; Fragiadakis, G. K.; Sellam, J.; Mariotti-Ferrandiz, E.; Klatzmann, D.; Gross, A.; Ye, C. J.; Butte, A. J.; Criswell, L.; Nakamura, M.; Sirota, M.
10.1101/2023.10.05.560352 — immunology — Posted on 2023-10-06
3687 The precision of signals encoding active self-movement
Haynes, J. D.; Gallagher, M.; Culling, J. F.; Freeman, T. C. A.
10.1101/2023.09.20.558633 — neuroscience — Posted on 2023-10-06
3689 DePARylation is critical for S phase progression and cell survival
Nie, L.; Wang, C.; Huang, M.; Liu, X.; Feng, X.; Tang, M.; Li, S.; Hang, Q.; Teng, H.; Shen, X.; Ma, L.; Gan, B.; Chen, J.
10.1101/2023.07.31.551317 — cancer biology — Posted on 2023-10-06
3691 Mitochondrial temperature homeostasis resists external metabolic stresses
Terzioglu, M.; Veeroja, K.; Montonen, T.; Ihalainen, T. O.; Salminen, T. S.; Benit, P.; Rustin, P.; Chang, Y.-T.; Takeharu, N.; Jacobs, H. T.
10.1101/2023.05.24.542069 — biochemistry — Posted on 2023-10-06
3693 Pharmacological cAMP stimulation via prostaglandin receptors rescues ciliary defects in CEP290-deficient patient and mouse models
de Malglaive, F.; Barny, I.; Machroub, S.; Fares-Taie, L.; Cano, E.; Goudin, N.; Attie-Bittach, T.; Kaplan, J.; Perrault, I.; Briseno-Roa, L.; Rozet, J.-M.; Annereau, J.-P.
10.1101/2023.10.06.561156 — genetics — Posted on 2023-10-06
3697 Retinoic Acid Boosts HIV-1 Replication in Macrophages via CCR5/SAMHD1-Dependent and mTOR-Modulated Mechanisms
Dias, J.; Cattin, A.; Goulet, J.-P.; Raymond Marchand, L.; Fert, A.; Wiche Salinas, T. R.; Ngassaki Yoka, C.-D.; Moreira Gabriel, E.; Caballero, E. R.; Routy, J.-P.; Ancuta, P.
10.1101/2023.10.05.561142 — immunology — Posted on 2023-10-06
3698 Neutrophil-derived IL-17 limits protective host responses and promotes tuberculosis pathogenesis
Sharma, P.; Sharma, R. D.; Das, M.; Sarkar, B.; Singh, L.; Jain, N.; Chaturvedi, S.; Mehra, L.; Rathee, A.; Sharma, S.; Shihui, F.; Lee, A.; Kumar, P. N.; Das, P.; Viswanathan, V.; Kornfeld, H.; Howland, S.; Babu, S.; Nandicoori, V.; Singhal, A.; Kumar, D.
10.1101/2023.10.05.561061 — immunology — Posted on 2023-10-06
3699 DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response 1 to oxidative stress
Hersperger, F.; Meyring, T.; Weber, P.; Chhatbar, C.; Monaco, G.; Dionne, M. S.; Paeschke, K.; Prinz, M.; Gross, O.; Classen, A.-K.; Kierdorf, K.
10.1101/2023.02.22.529599 — immunology — Posted on 2023-10-06
3700 A green alternative to fragrant agarwood sesquiterpenoid production
Gutierrez, S.; Overmans, S.; Wellman, G. B.; Samaras, V. G.; Oviedo, C.; Gede, M. M.; Szekely, G.; Lauersen, K. J.
10.1101/2023.10.06.561217 — synthetic biology — Posted on 2023-10-06
3704 Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms
Bendzunas, G.; Byrne, D. P.; Shrestha, S.; Daly, L. A.; Oswald, S. O.; Katiyar, S.; Venkat, A.; Yeung, W.; Eyers, C. E.; Eyers, P. A.; Kannan, N.
10.1101/2023.10.05.561145 — biochemistry — Posted on 2023-10-06
3705 The Translesion Polymerase Pol Y1 is a Constitutive Component of the B. subtilis Replication Machinery
Marrin, M. E.; Foster, M. R.; Santana, C. M.; Choi, Y.; Jassal, A. S.; Rancic, S. J.; Greenwald, C. R.; Drucker, M. N.; Thrall, E. S.
10.1101/2023.10.06.561215 — biochemistry — Posted on 2023-10-06
3707 Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland
Wiley, M. M.; Khatri, B.; Joachims, M. L.; Tessneer, K. L.; Stolarczyk, A. M.; Rasmussen, A.; Anaya, J.-M.; Aqrawi, L. A.; Bae, S.-C.; Baecklund, E.; Bjork, A.; Brun, J. G.; Bucher, S. M.; Dand, N.; Eloranta, M.-L.; Engelke, F.; Forsblad-d'Elia, H.; Fugmann, C.; Glenn, S. B.; Gong, C.; Gottenberg, J.-E.; Hammenfors, D.; Imgenberg-Kreuz, J.; Jensen, J. L.; Johnsen, S. J. A.; Jonsson, M. V.; Kelly, J. A.; Khanam, S.; Kim, K.; Kvarnstrom, M.; Mandl, T.; Martin, J.; Morris, D. L.; Nocturne, G.; Norheim, K. B.; Olsson, P.; Palm, O.; Pers, J.-O.; Rhodus, N. L.; Sjowall, C.; Skarstein, K.; Taylor, K.
10.1101/2023.10.05.561076 — genetics — Posted on 2023-10-06
3708 Spatial transcriptomics in adult Drosophila reveals new cell types in the brain and identifies subcellular mRNA patterns in muscles
Janssens, J.; Mangeol, P.; Hecker, N.; Partel, G.; Spanier, K.; Ismail, J. N.; Hulselmans, G. J.; Aerts, S.; Schnorrer, F.
10.1101/2023.10.06.561233 — developmental biology — Posted on 2023-10-06
3709 Chromosome Pairing Through Tensioned DNA Tethers Revealed by BRCA2 Meiotic Domain Deletion
Koornneef, L.; van Rossum-Fikkert, S. E.; Sleddens-Linkels, E.; Miron, S.; Maas, A.; van Loon, Y.; Barchi, M.; Zinn-Justin, S.; Essers, J.; Kanaar, R.; Baarends, W. M.; Zelensky, A. N.
10.1101/2023.10.06.561239 — molecular biology — Posted on 2023-10-06
3715 Response of soil bacteria to PUREX chemicals suggests biomarker utility and bioremediation potential
Podowski, J. C.; Forrester, S.; Antonopoulos, D. A.; Steeb, J. L.; Kent, A. D.; Davis, J. J.; Schabacker, D. S.
10.1101/2023.10.06.561230 — microbiology — Posted on 2023-10-06
3716 Bacterial cell surface nanoenvironment requires a specialized chaperone to activate a peptidoglycan biosynthetic enzyme
Delerue, T.; Chareyre, S.; Anantharaman, V.; Gilmore, M. C.; Popham, D. L.; Cava, f.; Aravind, L.; Ramamurthi, K. S.
10.1101/2023.10.06.561273 — microbiology — Posted on 2023-10-06
3717 Chimpanzees and bonobos reinstate an interrupted triadic game
Heesen, R.; Bangerter, A.; Zuberbuhler, K.; Iglesias, K.; Rossano, F.; Guery, J.-P.; Genty, E.
10.1101/2023.10.05.560857 — animal behavior and cognition — Posted on 2023-10-06
3718 FMNL2 regulates actin for ER and mitochondria distribution in oocyte meiosis
Pan, M.-H.; Pan, Z.-N.; Sun, M.-H.; Li, X.-H.; Ju, J.-Q.; Luo, S.-M.; Ou, X.-H.; Sun, S.
10.1101/2023.10.05.561058 — developmental biology — Posted on 2023-10-06
3724 Analysis of chronic host-aspergilloma interactions using a novel mouse model
Hamashima, R.; Tashiro, M.; Nakano, Y.; Namie, H.; Ito, Y.; Hirayama, T.; Takeda, K.; Iwanaga, N.; Nishi, K.; Liu, H.; Takazono, T.; Tanaka, T.; Watanabe, A.; Komohara, Y.; Furumoto, A.; Yanagihara, K.; Mukae, H.; Filler, S. G.; Takayama, K.; Izumikawa, K.
10.1101/2023.10.06.561242 — microbiology — Posted on 2023-10-06
3725 TMPRSS2 activation of Omicron lineage Spike glycoproteins is regulated by TMPRSS2 cleavage of ACE2
Aggarwal, A.; Fichter, C.; Milogiannakis, V.; Akerman, A.; Ison, T.; Ruiz Silva, M.; Esneau, C.; Bartlett, N.; Burrell, L.; Patel, S.; Churchill, M.; Angelovich, T.; Parry, R.; Sng, J. D.; Neely, G. G.; Moreno, C. L.; Loo, L.; Kelleher, A. D.; Brilot, F.; Khromykh, A.; Turville, S. G.
10.1101/2023.09.22.558930 — microbiology — Posted on 2023-10-06
3726 Fractional Amplitude of Low-Frequency Fluctuations Associated with Endocannabinoid, {micro}-Opioid and Dopamine Receptor Distributions in the Central Nervous System after High-Intensity Exercise Bouts
Boecker, H.; Maurer, A.; Daamen, M.; Bodensohn, L.; Werkhausen, J.; Lohaus, M.; Manunzio, C.; Manunzio, U.; Radbruch, A.; Attenberger, U.; Dukart, J.; Upadhyay, N.
10.1101/2023.10.06.561205 — neuroscience — Posted on 2023-10-06
3727 Discovery of a new activator of Slack potassium channels with robust efficacy in models of histamine-independent and chronic itch
Balzulat, A.; Zhu, W. F.; Flauaus, C.; Hernandez-Olmos, V.; Heering, J.; Sethumadhavan, S.; Dubiel, M.; Frank, A.; Menge, A.; Hebchen, M.; Metzner, K.; Lu, R.; Lukowski, R.; Ruth, P.; Knapp, S.; Mueller, S.; Steinhilber, D.; Haenelt, I.; Stark, H.; Proschak, E.; Schmidtko, A.
10.1101/2023.10.05.560997 — pharmacology and toxicology — Posted on 2023-10-06
3728 An ultrasensitive genetically encoded voltage indicator uncovers the electrical activity of non-excitable cells
Ruehl, P.; Nair, A. G.; Gawande, N.; Dehiwalage, S. N. C. W.; Muenster, L.; Schoenherr, R.; Heinemann, S. H.
10.1101/2023.10.05.560122 — biophysics — Posted on 2023-10-06
3729 The SAM Domain of EphA2 Inhibits Ligand-Independent Clustering and Activation
Shi, X.; Lingerak, R.; Shrestha, P.; Buck, M.; Wang, B.; Smith, A. W.
10.1101/2023.10.05.561050 — biophysics — Posted on 2023-10-06
3730 Deciphering Cancer Genomes with GenomeSpy: A Grammar-Based Visualization Toolkit
Lavikka, K.; Oikkonen, J.; Li, Y.; Muranen, T.; Micoli, G.; Marchi, G.; Lahtinen, A.; Huhtinen, K.; Lehtonen, R.; Hietanen, S.; Hynninen, J.; Virtanen, A.; Hautaniemi, S.
10.1101/2023.10.06.561159 — bioinformatics — Posted on 2023-10-06
3732 In vivo AGO-APP identifies a module of microRNAs cooperatively controlling exit from neural stem cell state
Narbonne-Reveau, K.; Erni, A.; Eichner, N.; Surbhi, S.; Meister, G.; Beclin, C.; Maurange, C.; Cremer, H.
10.1101/2023.10.05.560992 — developmental biology — Posted on 2023-10-06
3733 A Flat Protein Complex Shapes Rough ER Membrane Sheets
Sawyer, E. M.; Jensen, L. E.; Meehl, J. B.; Larsen, K. P.; Petito, D. A.; Hurley, J. H.; Voeltz, G. K.
10.1101/2023.10.06.559866 — cell biology — Posted on 2023-10-06
3735 Intrinsic disorder specifies discreet functions of nucleoplasmin-like histone chaperones
Gauthier, C. M.; LeGallais, J.; Savic, N.; Moradi Fard, S.; Grew, A.; Loe, M.; Kirlikaya, B.; Cobb, J. A.; Nelson, C. J.
10.1101/2023.10.06.560522 — molecular biology — Posted on 2023-10-06
3738 Potential use of Sodium Butyrate (SB) as an anti-virulence agent against Vibrio cholerae targeting ToxT virulence protein.
Kundu, S.; Das, S.; Maitra, P.; Halder, P.; Koley, H.; Mukhopadhyay, A. K.; MIYOSHI, S.-I.; Dutta, S.; Chatterjee, N. S.; Bhattacharya, S.
10.1101/2023.10.05.561138 — microbiology — Posted on 2023-10-06
3739 Traumatic brain injury disrupts state-dependent functional cortical connectivity in a mouse model
Bottom-Tanzer, S.; Corella, S.; Meyer, J.; Sommer, M.; Bolanos, L.; Murphy, T.; Quinones, S.; Heiney, S.; Shtrahman, M.; Whalen, M.; Oren, R.; Higley, M. J.; Cardin, J. A.; Noubary, F.; Armbruster, M.; Dulla, C.
10.1101/2023.10.06.560776 — neuroscience — Posted on 2023-10-06
3740 LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology spread
Lubben, N.; Brynildsen, J. K.; Leyns, C. E. G.; Webb, C. M.; Li, H. L.; Changolkar, L.; Zhang, B.; Meymand, E.; O'Reilly, M.; Madaj, Z.; DeWeerd, D.; Fell, M. J.; Lee, V. M. Y.; Bassett, D. S.; Henderson, M. X.
10.1101/2023.10.06.561190 — neuroscience — Posted on 2023-10-06
3741 Neural Correlates of Self-Referential Belief Processes
Bruns, E.; Scholz, I.; Koppe, G.; Kirsch, P.; Gerchen, M. F.
10.1101/2023.10.05.561046 — neuroscience — Posted on 2023-10-06
3743 Geometric constraint of mechanosensing in bone marrow stromal cell cultures prevents stiffness-induced differentiation
Hernandez-Miranda, M. L.; Xu, D.; Johnston, D. A.; Browne, M.; Cook, R. B.; Sengers, B. G.; Evans, N. D.
10.1101/2023.10.05.560162 — biophysics — Posted on 2023-10-06
3745 Characterizing cell-type spatial relationships across length scales in spatially resolved omics data
dos Santos Peixoto, R.; Miller, B. F.; Brusko, M. A.; Atta, L.; Anant, M.; Atkinson, M. A.; Brusko, T. M.; Wasserfall, C. H.; Fan, J.
10.1101/2023.10.05.560733 — bioinformatics — Posted on 2023-10-06
3747 NAMERS: a purpose-built reference DNA sequence database to support applied eDNA metabarcoding
Westfall, K. M.; Singer, G. A. C.; Kaushal, M.; Gilmore, S. R.; Fahner, N.; Hajibabaei, M.; Abbott, C. L.
10.1101/2023.10.06.561210 — genetics — Posted on 2023-10-06
3749 Population-specific responses to developmental temperature in the arboviral vector : implications for climate change
Carlassara, M.; Khorramnejad, A.; Oker, H.; Bahrami, R.; Lozada-Chavez, A. N.; Mancini, M. V.; Body, M. J.; Lahondere, C.; Bonizzoni, M.
10.1101/2023.10.06.561151 — ecology — Posted on 2023-10-06
3751 RNA structure modulates Cas13 activity and enables mismatch detection
Kimchi, O.; Larsen, B. B.; Dunkley, O. R.; te Velthuis, A. J. W.; Myhrvold, C.
10.1101/2023.10.05.560533 — molecular biology — Posted on 2023-10-06
3752 Heterologous booster with a novel formulation containing glycosylated trimeric S protein is effective againstOmicron
Bottero, D.; Rudi, E.; Aispuro, P. M.; Zurita, M. E.; Gaillard, M. E.; Ledesma, M. M. G. L.; Malito, J.; Stuible, M.; Ambrosis, N. M.; Durocher, Y.; Gamarnik, A.; Wigdorovitz, A.; Hozbor, D.
10.1101/2023.10.05.557343 — immunology — Posted on 2023-10-06
3753 Quantifying Adaptive Evolution of the Human Immune Cell Landscape
Salvador-Martinez, I.; Murga-Moreno, J.; Nieto, J. C.; Alsinet, C.; Enard, D.; Heyn, H.
10.1101/2023.10.06.559946 — immunology — Posted on 2023-10-06
3755 Fine-tuning FAM161A gene augmentation therapy to restore retinal function
Arsenijevic, Y.; Chang, N.; Mercey, O.; El Fersioui, Y.; Koskiniemi-Kuendig, H.; Joubert, C.; Bemelmans, A.-P.; Rivolta, C.; Banin, E.; Sharon, D.; Guichard, P.; Hamel, V.; Kostic, C.
10.1101/2023.10.06.561164 — neuroscience — Posted on 2023-10-06
3757 An integrated transcriptomic cell atlas of human neural organoids
He, Z.; Dony, L.; Fleck, J. S.; Szalata, A.; Li, K. X.; Sliskovic, I.; Lin, H.-C.; Santel, M.; Atamian, A.; Quadrato, G.; Sun, J.; Pasca, S. P.; Camp, G.; Theis, F.; Treutlein, B.
10.1101/2023.10.05.561097 — developmental biology — Posted on 2023-10-06
3758 Draft Genomes of Four Kluyveromyces marxianus Isolates Retrieved from the Elaboration Process of Henequen (Agave fourcroydes) Mezcal.
Lozano-Aguirre Beltran, L. F.; Avitia, M.; Lappe-Oliveras, P.; Licona-Cassani, C.; Cevallos, M. A.; Le Borgne, S.
10.1101/2023.10.03.560785 — microbiology — Posted on 2023-10-06
3759 A comparison of short-read, HiFi long-read, and hybrid strategies for genome-resolved metagenomics
Eisenhofer, R.; Nesme, J.; Santos-Bay, L.; Koziol, A.; Sorensen, S. J.; Alberdi, A.; Aizpurua, O.
10.1101/2023.10.04.560907 — microbiology — Posted on 2023-10-06
3761 Mesoscale Ca2+ imaging reveals networks of Purkinje cell dendritic and somatic modulation, with divergent roles of activity versus correlation during behavior
Streng, M. L.; Carter, R. E.; Kottke, B. W.; Togneri, K.; Wasserman, E.; Rajendran, V.; Krook-Magnuson, E.; kodandaramaiah, S. B.; Ebner, T.
10.1101/2023.10.05.561090 — neuroscience — Posted on 2023-10-06
3763 Multi-donor human cortical Chimeroids reveal individual susceptibility to neurotoxic triggers
Anton-Bolanos, N.; Faravelli, I.; Faits, T.; Andreadis, S.; Trattaro, S.; Kastli, R.; Adiconis, X.; Di Bella, D. J.; Tegtmeyer, M.; Nehme, R.; Levin, J. Z.; Regev, A.; Arlotta, P.
10.1101/2023.10.05.558331 — neuroscience — Posted on 2023-10-06
3765 Neuroprotective Effects of Naltrexone in a Mouse Model of Post-Traumatic Epilepsy
Rodriguez, S.; Sharma, S.; Tiarks, G.; Peterson, Z.; Jackson, K.; Thedens, D. R.; Wong, A.; Keffala-Gerhard, D.; Mahajan, V. B.; Ferguson, P. J.; Newell, E.; Glykys, J.; Nickl-Jockschat, T.; Bassuk, A. G.
10.1101/2023.10.04.560949 — neuroscience — Posted on 2023-10-06
3768 Four-dimensional quantitative analysis of cell plate development using lattice light sheet microscopy identifies robust transition points between growth phases
Sinclair, R. M.; Wang, M.; Jawaid, M. Z.; Aaron, J.; Rossetti, B.; Wait, E.; McDonald, K.; Cox, D.; heddleston, J.; Wilkop, T.; Drakakaki, G.
10.1101/2023.10.03.560767 — plant biology — Posted on 2023-10-06
3771 Eliminating steam pops and improving lesion safety in atrial ablation with conductive hydrogels
Post, A. D.; Jaworski, L.; Bernard, D.; Goal, S.; Zhang, H. D.; Nkansah, A.; Cosgriff-Hernandez, E.; Razavi, M.
10.1101/2023.10.03.560762 — bioengineering — Posted on 2023-10-06
3773 High-throughput single-nucleus hybrid sequencing reveals genome-transcriptome correlations in cancer
Li, S.; Alexander, J.; Kendall, J.; Andrews, P.; Rose, E.; Orjuela, H.; Park, S.; Podszus, C.; Shanley, L.; Ma, R.; Ranade, N.; Ronemus, M.; Rishi, A.; Donoho, D. L.; Goldberg, G. L.; Levy, D.; Wigler, M.
10.1101/2023.10.04.560973 — genomics — Posted on 2023-10-06
3775 Non-linear phylogenetic regression using regularized kernels
Rosas-Puchuri, U.; Santaquiteria, A.; Khanmohammadi, S.; Solis-Lemus, C.; Betancur-R., R.
10.1101/2023.10.04.560983 — evolutionary biology — Posted on 2023-10-06
3776 The landscape of ancient human pathogens in Eurasia from the Stone Age to historical times
Sikora, M.; Canteri, E.; Fernandez-Guerra, A.; Oskolkov, N.; Agren, R.; Hansson, L.; Irving-Pease, E. K.; Muehlemann, B.; Holtsmark Nielsen, S.; Scorrano, G.; Allentoft, M. E.; Seersholm, F. V.; Schroeder, H.; Gaunitz, C.; Stenderup, J.; Vinner, L.; Jones, T. C.; Nystedt, B.; Parkhill, J.; Fugger, L.; Racimo, F.; Kristiansen, K.; Iversen, A. K. N.; Willerslev, E.
10.1101/2023.10.06.561165 — evolutionary biology — Posted on 2023-10-06
3779 Activity-dependent survival of odorant receptor neurons in ants
Sieriebriennikov, B.; Sieber, K. R.; Kolumba, O.; Mlejnek, J.; Jafari, S.; Yan, H.
10.1101/2023.10.04.560961 — developmental biology — Posted on 2023-10-06
3783 Pumping the brakes: Rostromedial tegmental inhibition of compulsive cocaine seeking
Vento, P. J.; Watson, J. R.; Pullmann, D.; Black, S. L.; Tomberlin, J. S.; Jhou, T. C.
10.1101/2023.10.04.560908 — neuroscience — Posted on 2023-10-06
3784 APOE, Immune Factors, Sex, and Diet Interact to Shape Brain Networks in Mouse Models of Aging
Winter, S.; Mahzarnia, A.; Anderson, R. J.; Han, Z. Y.; Tremblay, J. J.; Marcellino, D.; Dunson, D.; Badea, A.
10.1101/2023.10.04.560954 — neuroscience — Posted on 2023-10-06
3786 Aperiodic component of EEG power spectrum and cognitive performance in aging: the role of education
Montemurro, S.; Borek, D.; Marinazzo, D.; Zago, S.; Masina, F.; Filippini, N.; Arcara, G.
10.1101/2023.10.05.560988 — neuroscience — Posted on 2023-10-06
3787 Heterogeneity in Functional Connectivity: Dimensional Predictors of Individual Variability during Rest and Task fMRI in Psychosis
Secara, M. T.; Oliver, L. D.; Gallucci, J.; Dickie, E. W.; Foussias, G.; Gold, J.; Malhotra, A. K.; Buchanan, R. W.; Voineskos, A. N.; Hawco, C.
10.1101/2023.10.04.560971 — neuroscience — Posted on 2023-10-06
3788 ModelSEED v2: High-throughput genome-scale metabolic model reconstruction with enhanced energy biosynthesis pathway prediction
Faria, J. P.; Liu, F.; Edirisinghe, J. N.; Gupta, N.; Seaver, S. M. D.; Freiburger, A. P.; Zhang, Q.; Weisenhorn, P.; Conrad, N.; Zarecki, R.; Song, H.-S.; DeJongh, M.; Best, A. A.; Cottingham, R. W.; Arkin, A. P.; Henry, C. S.
10.1101/2023.10.04.556561 — systems biology — Posted on 2023-10-06
3789 Hypoxic injury triggers maladaptive repair in human kidney organoids
Nunez-Nescolarde, A. B.; Piran, M.; Perlaza-Jimenez, L.; Barlow, C. K.; Steele, J. R.; Deveson, D.; Lee, H.-C.; Moreau, J. L. M.; Schittenhelm, R. B.; Nikolic-Paterson, D. J.; Combes, A. N.
10.1101/2023.10.04.558359 — systems biology — Posted on 2023-10-06
3790 Unleashing the secrets of plant-fungal interactions using a transformation-free confocal staining technique that supports AI-assisted quantitative analysis
Nelson, A. C.; Kariyawasam, G.; Wyatt, N. A.; Li, J.; Haueisen, J.; Stukenbrock, E. H.; Borowicz, P.; Liu, Z.; Friesen, T. L.
10.1101/2023.10.04.560942 — plant biology — Posted on 2023-10-06
3793 The effects of resistance training on denervated myofibers, senescent cells, and associated protein markers in middle-aged adults
Ruple, B.; Mattingly, M.; Godwin, J.; McIntosh, M.; Kontos, N.; Agyin-Birikorang, A.; Michel, J. M.; Plotkin, D.; Chen, S.-Y.; Ziegenfuss, T.; Fruge, A.; Gladden, L. B.; Robinson, A.; Mobley, C. B.; Mackey, A. L.; Roberts, M.
10.1101/2023.10.04.560958 — physiology — Posted on 2023-10-06
3795 Single nuclei chromatin accessibility and transcriptomic map of breast tissues of women of diverse genetic ancestry
Bhat-Nakshatri, P.; Gao, H.; Khatpe, A. S.; McGuire, P. C.; Erdogan, C.; Chen, D.; Jiang, G.; New, F.; German, R.; Storniolo, A. M.; Liu, Y.; Nakshatri, H.
10.1101/2023.10.04.560911 — cancer biology — Posted on 2023-10-06
3800 A portable, easy-to-use paper-based biosensor for rapid in-field detection of fecal contamination on fresh produce farms
Wang, J.; Kaur, S.; Kayabasi, A.; Ranjbaran, M.; Rath, I.; Benschikovski, I.; Raut, B.; Ra, K.; Rafiq, N.; Verma, M. S.
10.1101/2023.10.04.560915 — bioengineering — Posted on 2023-10-06
3803 Large-scale discovery of potent, compact and lineage specific enhancers for gene therapy vectors
Psatha, N.; Sova, P.; Georgolopoulos, G.; Paschoudi, K.; Iwata, M.; Bloom, J.; Ulyanova, T.; Wang, H.; Kirtsou, A.; Vasiloudis, N.-I.; Wilken, M. S.; Stamatoyannopoulos, J. A.; Yannaki, E.; Papayannopoulou, T.; Stamatoyannopoulos, G.; Vierstra, J.
10.1101/2023.10.04.559165 — genomics — Posted on 2023-10-06
3808 Evaluating the definition and distribution of spring ephemeral wildflowers in eastern North America
Yancy, A. J.; Lee, B. R.; Kuebbing, S. E.; Neufeld, H. S.; Spicer, M. E.; Heberling, J. M.
10.1101/2023.10.04.560873 — ecology — Posted on 2023-10-06
3811 Dedifferentiated early postnatal lung myofibroblasts redifferentiate in adult disease
Chandran, R. R.; Adams, T.; Kabir, I.; Gallardo, E.; Kaminski, N.; Gomperts, B.; Greif, D.
10.1101/2023.10.04.560924 — developmental biology — Posted on 2023-10-06
3813 Metabolic syndrome in New Zealand Obese mice promotes microglial-vascular interactions and reduces microglial plasticity
MacLean, M.; Marola, O. J.; Cossette, T.; Diemler, C.; Hewes, A. A.; Keezer, K. J.; Onos, K. D.; Howell, G. R.
10.1101/2023.10.04.560877 — neuroscience — Posted on 2023-10-06
3818 A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia
Klein, K.; Kollmann, S.; List, J.; Hiesinger, A.; Kender, J.; Rhandawa, M.; Trifinopoulos, J.; Maurer, B.; Grausenburger, R.; Moriggl, R.; Ruelicke, T.; Witalisz-Siepracka, A.; Walter, W.; Hoermann, G.; Sexl, V.; Gotthardt, D.
10.1101/2023.10.04.560502 — cancer biology — Posted on 2023-10-06
3819 Federated Learning for multi-omics: a performance evaluation in Parkinson's disease
Danek, B. P.; Makarious, M. B.; Dadu, A.; Vitale, D.; Nalls, M. A.; Sun, J.; Faghri, F.
10.1101/2023.10.04.560604 — bioinformatics — Posted on 2023-10-06
3823 Mitochondrial background can explain variable costs of immune deployment
Kutzer, M. A. M.; Cornish, B.; Jamieson, M.; Zawistowska, O.; Monteith, K. M.; Vale, P. F.
10.1101/2023.10.04.560830 — evolutionary biology — Posted on 2023-10-06
3825 Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5
Wang, L. T.; Cooper, A. J. R.; Farrell, B.; Miura, K.; Diouf, A.; Muller-Sienerth, N.; Crosnier, C.; Purser, L.; Maciuszek, M.; Barrett, J. R.; McHugh, K.; Tucker, C.; Li, S.; Doumbo, S.; Doumtabe, D.; Pyo, C.-W.; Nielsen, C. M.; Silk, S. E.; Kayentao, K.; Ongoiba, A.; Zhao, M.; Nguyen, D. C.; Lee, F. E.-H.; Minassian, A. M.; Geraghty, D. E.; Traore, B.; Seder, R. A.; Crompton, P. D.; Wright, G. J.; Long, C. A.; Draper, S. J.; Higgins, M. K.; Tan, J.
10.1101/2023.10.04.560669 — immunology — Posted on 2023-10-06
3828 Spatially specific, closed-loop infrared thalamocortical deep brain stimulation
Coventry, B. S.; Lawlor, G. L.; Bagnati, C. B.; Krogmeier, C.; Bartlett, E. L.
10.1101/2023.10.04.560859 — neuroscience — Posted on 2023-10-06
3834 VIBE: An R-package for advanced RNA-seq data exploration, disease stratification and therapeutic targeting
Khatri, I.; Asten, S. D. v.; Moreno, L. F.; Higgs, B. W.; Klijn, C.; Blokzijl, F.; Kolder, I. C.
10.1101/2023.10.04.560641 — bioinformatics — Posted on 2023-10-06
3835 Multimodal single-cell profiling of T cell specificity and reactivity in lung cancer
Bieberich, F.; Vazquez-Lombardi, R.; Jin, H.; Hong, K.-L.; Herzig, P.; Trefny, M.; Trueb, M.; Laubli, H.; Lardinois, D.; Mertz, K.; Matter, M.; Zippelius, A.; Reddy, S. T.
10.1101/2023.10.04.560863 — immunology — Posted on 2023-10-06
3836 Juxtacrine DLL4-NOTCH1 signaling between astrocytes drives neuroinflammation via the IL-6-STAT3 axis
Mora, P.; Laisne, M.; Bourguignon, C.; Rouault, P.; Renault, M. A.; Horng, S.; Couffinhal, T.; Chapouly, C.
10.1101/2023.10.04.560826 — neuroscience — Posted on 2023-10-06
3837 Classification of bioactive peptides: a comparative analysis of models and encodings
Bizzotto, E.; Zampieri, G.; Treu, L.; Filannino, P.; Di Cagno, R.; Campanaro, S.
10.1101/2023.10.04.560809 — bioinformatics — Posted on 2023-10-06
3838 Ultrasound-Induced Reorientation for Multi-Angle Optical Coherence Tomography
Kvale Lovmo, M.; Deng, S.; Moser, S.; Leitgeb, R.; Drexler, W.; Ritsch-Marte, M.
10.1101/2023.10.04.560819 — bioengineering — Posted on 2023-10-06
3839 Recurrent hybridization and gene flow shaped Norway and Siberian spruce evolutionary history over multiple glacial cycles
Zhou, Q.; Karunarathne, P.; Andersson-Li, L.; Chen, C.; Opgenoorth, L.; Heer, K.; Vendramin, G. G.; Piotti, A.; Nakvasina, E.; Lascoux, M.; Milesi, P.
10.1101/2023.10.04.560811 — evolutionary biology — Posted on 2023-10-06
3841 Innate immune memory after brain injury drives inflammatory cardiac dysfunction
Simats, A.; Zhang, S.; Messerer, D.; Cao, J.; Chong, F.; Besson-Girard, S.; Carofiglio, O.; Filser, S.; Plesnila, N.; Braun, C.; Gokce, O.; Dichgans, M.; Hatakeyama, K.; Bonev, B.; Beltran, E.; Schulz, C.; Liesz, A.
10.1101/2023.10.04.560805 — immunology — Posted on 2023-10-06
3848 Integrating microbial abundance time series with fermentation dynamics of the rumen microbiome via mathematical modelling
Davoudkhani, M.; Rubino, F.; Creevey, C. J.; Ahvenjarvi, S.; Bayat, A. R.; Tapio, I.; Belanche, A.; Munoz-Tamayo, R.
10.1101/2023.10.05.560454 — systems biology — Posted on 2023-10-06
3849 The RAD51 paralogue HvXRCC2 regulates meiosis and recombination in barley
Colas, I.; Macaulay, M.; Arrieta, M.; Schreiber, M.; Sandhu, A.; Augustine, A.; Targonska-Karasek, M.; Armstrong, S.; Waugh, R.; Ramsay, L.
10.1101/2023.10.05.561044 — plant biology — Posted on 2023-10-06
3851 Harnessing Landrace Diversity Empowers Wheat Breeding for Climate Resilience
Cheng, S.; Feng, C.; Wingen, L. U.; Cheng, H.; Riche, A. B.; Jiang, M.; Leverington-Waite, M.; Huang, Z.; Collier, S.; Orford, S.; Wang, X.; Awal, R.; Barker, G.; O'Hara, T.; Lister, C.; Siluveru, A.; Quiroz-Chavez, J.; Ramirez-Gonzalez, R. H.; Bryant, R.; Berry, S.; Bansal, U.; Bariana, H. S.; Bennett, M. J.; Bicego, B.; Bilham, L.; Brown, J. K. M.; Burridge, A.; Burt, C.; Buurman, M.; Castle, M.; Chartrain, L.; Chen, B.; Denbel, W.; Elkot, A. F.; Fenwick, P.; Feuerhelm, D.; Foulkes, J.; Gaju, O.; Gauley, A.; Gaurav, K.; Hafeez, A. N.; Han, R.; Horler, R.; Hou, J.; Iqbal, M. S.; Kerton, M.; K
10.1101/2023.10.04.560903 — plant biology — Posted on 2023-10-06
3852 Epigenetic field defect discriminates normal tissues from healthy and tumor-bearing kidneys
Serth, J.; Reese, C.; Hubscher, T.; Hill, B.; Klintschar, M.; Hennenlotter, J.; Kuczyk, M. A.
10.1101/2023.10.05.560844 — cancer biology — Posted on 2023-10-06
3854 Cross-Tissue Specificity of Pediatric DNA Methylation Associated with Cumulative Family Adversity
Chan, M. H.-M.; Merrill, S. M.; Fatima, F.; MacIsaac, J. L.; Obradovic, J.; Boyce, W. T.; Kobor, M. S.
10.1101/2023.10.04.559423 — genomics — Posted on 2023-10-06
3858 Rapid evolution of pesticide resistance via adaptation and interspecific introgression in a major North American crop pest
North, H. L.; Fu, Z.; Metz, R.; Stull, M. A.; Johnson, C. D.; Shirley, X.; Crumley, K.; Reisig, D.; Kerns, D. L.; Gilligan, T.; Walsh, T.; Jiggins, C. D.; Sword, G.
10.1101/2023.10.04.560869 — evolutionary biology — Posted on 2023-10-06
3862 Bacteroides is increased in an autism cohort and induces autism-relevant behavioral changes in mice in a sex-dependent manner
Carmel, J.; Ghanayem, N.; Maayouf, R.; Saleev, N.; Chaterjee, I.; Getselter, D.; Tiknonov, E.; Turjeman, S.; Shaalan, M.; Khatib, S.; Kuzminsky, A.; Kvetniy- Ferdman, N.; Kronos, T.; Bretler, T.; Koren, O.; Elliott, E.
10.1101/2023.10.05.560465 — neuroscience — Posted on 2023-10-06
3863 The interpeduncular nucleus blunts the rewarding effect of nicotine
Jehl, J.; Ciscato, M.; Vicq, E.; Dejean de la Batie, G.; Guyon, N.; Mondoloni, S.; Frangieh, J.; Nguyen, C.; Hardelin, J.-P.; Marti, F.; Corringer, P.-J.; Faure, P.; Mourot, A.
10.1101/2023.10.05.561018 — neuroscience — Posted on 2023-10-06
3865 The developmental trajectory of 1H-MRS brain metabolites from childhood to adulthood.
Thomson, A.; Hwa, H.; Pasanta, D.; Hopwood, B.; Powell, H.; Lawrence, R.; Gracia-Tabuenca, Z.; Arichi, T.; Edden, R.; Chai, X. J.; Puts, N.
10.1101/2023.10.05.560892 — neuroscience — Posted on 2023-10-06
3867 Morpho-electric and computational properties of three types of human hippocampal CA1 pyramidal neurons
Mertens, E.; Leibner, Y.; Pie, J.; Galakhova, A.; Waleboer, F.; Meijer, J.; Heistek, T.; Wilbers, R.; Heyer, D.; Goriounova, N.; Idema, S.; Verhoog, M.; Kalmbach, B.; Lee, B.; Gwinn, R.; Lein, E.; Aronica, E.; Ting, J.; Mansvelder, H.; Segev, I.; de Kock, C.
10.1101/2023.10.05.561029 — neuroscience — Posted on 2023-10-06
3868 Beyond the nucleus: Plastic chemicals activate G protein-coupled receptors
McPartland, M.; Stevens, S.; Bartosova, Z.; Gisnaas Vardeberg, I.; Voelker, J.; Wagner, M.
10.1101/2023.10.04.560665 — pharmacology and toxicology — Posted on 2023-10-06
3869 Chemokine profiling of melanoma-macrophage crosstalk identifies CCL8 and CCL15 as prognostic factors in cutaneous melanoma
Barrio-Alonso, C.; Nieto-Valle, A.; Garcia-Martinez, E.; Gutierrez-Seijo, A.; Parra-Blanco, V.; Marquez-Rodas, I.; Aviles-Izquierdo, J. A.; Sanchez-Mateos, P.; Samaniego, R.
10.1101/2023.10.04.560856 — cancer biology — Posted on 2023-10-06
3874 Human intestinal organoids with an autologoustissue-resident immune compartment
Recaldin, T.; Gjeta, B.; Steinacher, L.; Harter, M. F.; Adam, L.; Nikolaev, M.; Krese, R.; Kilik, U.; Popovic, D.; Almato-Bellavista, M.; Kromer, K.; Bscheider, M.; Cabon, L.; Camp, J. G.; Gjorevski, N.
10.1101/2023.10.04.560810 — immunology — Posted on 2023-10-06
3875 Cell-autonomous targeting of arabinogalactan by host immune factors inhibits mycobacterial growth
Qin, L.; Xu, J.; Chen, J.; Wang, S.; Zheng, R.; Cui, Z.; Liu, Z.; Wu, X.; Wang, J.; Huang, X.; Wang, Z.; Wang, M.; Pan, R.; Kaufmann, S. H.; Meng, X.; Zhang, L.; Sha, W.; Liu, H.
10.1101/2023.10.05.561003 — immunology — Posted on 2023-10-06
3876 LGI1 autoantibodies enhance synaptic transmission by presynaptic Kv1 loss and increased action potential broadening
Ritzau-Jost, A.; Gsell, F.; Sell, J.; Sachs, S.; Montanaro, J.; Kirmann, T.; Maass, S.; Irani, S. R.; Werner, C.; Geis, C.; Sauer, M.; Shigemoto, R.; Hallermann, S.
10.1101/2023.10.04.560631 — neuroscience — Posted on 2023-10-06
3879 Single-cell gene expression prediction from DNA sequence at large contexts
Schwessinger, R.; Deasy, J.; Woodruff, R. T.; Young, S.; Branson, K. M.
10.1101/2023.07.26.550634 — genomics — Posted on 2023-10-06
3881 The molecular basis of Abelson kinase regulation by its αI-helix
Paladini, J.; Maier, A.; Habazettl, J. M.; Hertel, I.; Sonti, R.; Grzesiek, S.
10.1101/2023.10.04.560671 — biophysics — Posted on 2023-10-06
3888 Identifying predictors of survival in patients with leukemia using single-cell mass cytometry and machine learning
Kleftogiannis, D.; Tislevoll, B. S.; van der Meer, N.; Motzfeldt, I. K. F.; Hellesoy, M.; Gullaksen, S.-E.; Griessinger, E.; Fagerholt, O.; Lenartova, A.; Floisand, Y.; Schuringa, J. J.; Gjertsen, B. T.; Jonassen, I.
10.1101/2022.08.13.503587 — bioinformatics — Posted on 2023-10-06
3890 Gene Novelties in Amphioxus Illuminate the Early Evolution of Deuterostomes
Xiong, Q.; Yang, K. Y.; Zeng, X.; Wang, M.; Ng, P. K.-S.; Zhou, J.-W.; Ng, J. K.-W.; Law, C. T.-Y.; Du, Q.; Xu, K.; Falkenberg, L. J.; Mao, B.; Chen, J.-Y.; Tsui, S. K.-W.
10.1101/2022.05.18.492404 — evolutionary biology — Posted on 2023-10-06
3891 Longitudinal Survey of Astrovirus infection in different bat species in Zimbabwe: Evidence of high genetic Astrovirus diversity
Chidoti, V.; De Nys, H.; Abdi, M.; Mashura, G.; Pinarello, V.; Chiweshe, N.; Matope, G.; Guerrini, L.; Pfulenyi, D.; Cappelle, J.; Mwandiringana, E.; Misse, D.; Elizabeth, G.; Bourgarel, M.; Liegeois, F.
10.1101/2023.04.14.536987 — molecular biology — Posted on 2023-10-05
3895 Cis-regulatory modes of Ultrabithorax inactivation in butterfly forewings
Tendolkar, A.; Mazo-Vargas, A.; Livraghi, L.; Hanly, J. J.; Van Horne, K. C.; Gilbert, L. E.; Martin, A.
10.1101/2023.08.18.553910 — genomics — Posted on 2023-10-05
3896 The overlapping genetic architecture of psychiatric disorders and cortical brain structure
Sha, Z.; Warrier, V.; Bethlehem, R. A. I.; Schultz, L. M.; Merikangas, A. K.; Sun, K. Y.; Gur, R. C.; Gur, R. E.; Shinohara, R. T.; Seidlitz, J.; Almasy, L.; Andreassen, O.; Alexander-Bloch, A.
10.1101/2023.10.05.561040 — genetics — Posted on 2023-10-05
3901 Study-Phase Reinstatement: Encoding Spontaneous Thoughts as Memories
Halpern, D.; Lega, B.; Gross, R. E.; Sperling, M. R.; Wu, C.; Aronson, J. P.; Jobst, B. C.; Kahana, M. J.
10.1101/2023.10.04.560946 — neuroscience — Posted on 2023-10-05
3903 Synaptic Basis of Behavioral Timescale Plasticity
Gonzalez, K. C.; Negrean, A.; Liao, Z.; Polleux, F.; Losonczy, A.
10.1101/2023.10.04.560848 — neuroscience — Posted on 2023-10-05
3905 CaCO3 Nanoparticles Delivering MicroRNA-200c Suppress Oral Squamous Cell Carcinoma
Ding, Q.; Remy, M. T.; Upara, C.; Hu, J.; Mata, A. M.; Haes, A. J.; Lanzel, E.; Sun, H.; Buchakjian, M.; Hong, L.
10.1101/2023.10.05.561110 — bioengineering — Posted on 2023-10-05
3912 Broad variation in response of individual introns to splicing inhibitors in a humanized yeast strain
Hunter, O.; Talkish, J.; Quick-Cleveland, J.; Igel, H.; Tan, A.; Kuersten, S.; Katzman, S.; Donohue, J. P.; Jurica, M. S.; Ares, M.
10.1101/2023.10.05.560965 — molecular biology — Posted on 2023-10-05
3914 Bioelectrical antimicrobial susceptivity testing (BeAST) with the budding yeast S. cerevisiae
de Souza-Guerreiro, T. C.; Huan Bacellar, L.; Santana da Costa, T.; Tasic, L.; Asally, M.
10.1101/2023.10.05.561038 — microbiology — Posted on 2023-10-05
3919 DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces
Miron, S.; Legrand, P.; van Rossum-Fikkert, S. E.; Ristic, D.; Badar, A.; Kanaar, R.; Zinn-Justin, S.; Zelensky, A. N.
10.1101/2023.10.05.561053 — biochemistry — Posted on 2023-10-05
3920 Structural and molecular basis of choline uptake into the brain by FLVCR2
Cater, R. J.; Mukherjee, D.; Gil Iturbe, E.; Erramilli, S. K.; Chen, T.; Koo, K.; Santander, N. G.; Reckers, A. R.; Kloss, B.; Gawda, T.; Choy, B. C.; Zhang, Z.; Clarke, O. B.; Yee, S. W.; Kossiakoff, A. K.; Quick, M.; Arnold, T.; Mancia, F.
10.1101/2023.10.05.561059 — biochemistry — Posted on 2023-10-05
3921 Targeting LC3/GABARAP for degrader development and autophagy modulation
Schwalm, M. P.; Dopfer, J.; Kumar, A.; Greco, F. A.; Bauer, N.; Loehr, F.; Heering, J.; Cano, S.; Lechner, S.; Hanke, T.; Bekic, I.; Morasch, V.; Fearon, D.; Marples, P. G.; Tomlinson, C. W. E.; Brunello, L.; Saxena, K.; Adams, N.; von-Delft, F.; Mueller, S.; Kuester, B.; Stolz, A.; Proschak, E.; Knapp, S.; Rogov, V. V.
10.1101/2023.10.05.560930 — biochemistry — Posted on 2023-10-05
3922 Dissecting telomerase RNA structural heterogeneity in living human cells with DMS-MaPseq
Forino, N. M.; Woo, J. Z.; Zaug, A. J.; Jimenez, A. G.; Cech, T. R.; Rouskin, S.; Stone, M.
10.1101/2023.10.04.560962 — biochemistry — Posted on 2023-10-05
3923 Measuring carbohydrate recognition profile of lectins on live cells using liquid glycan array (LiGA)
Sojitra, M.; Schmidt, E. N.; Lima, G. M.; Carpenter, E. J.; McCord, K. A.; Atrazhev, A.; Macauley, M. S.; Derda, R.
10.1101/2023.10.04.559794 — biochemistry — Posted on 2023-10-05
3925 Single-cell bisulfite-free 5mC and 5hmC sequencing with high sensitivity and scalability
Cao, Y.; Bai, Y.; Yuan, T.; Song, L.; Fan, Y.; Ren, L.; Song, W.; Peng, J.; An, R.; Gu, Q.; Zheng, Y.; Xie, X. S.
10.1101/2023.10.04.560836 — genomics — Posted on 2023-10-05
3929 A novel in vivo system to study coral biomineralization in the starlet sea anemone (Nematostella vectensis)
Foster, B.; Hugosson, F.; Scucchia, F.; Enjolras, C.; Babonis, L.; Hoaen, W.; Martindale, M. Q.
10.1101/2023.10.04.560932 — molecular biology — Posted on 2023-10-05
3930 Detection of Mycobacterium tuberculosis in human tissue via RNA in situ hybridization
Nargan, k.; Naidoo, T.; Msimang, M.; Nadeem, S.; Wells, G.; Hunter, R. L.; Hutton, A.; Lumamba, K.; Glasgow, J. N.; Benson, P. V.; Steyn, A. J.
10.1101/2023.10.04.560963 — microbiology — Posted on 2023-10-05
3931 Investigating the Rescue Potential of Fecal Microbiota Transplants in Anorexia Nervosa using Antibiotic-treated Mice in a Split Group Cross-Over Study
Maschek, S.; Ostergaard, T. H.; Krych, L.; Zachariassen, L. F.; Sorensen, D. B.; Mentzel, C. M. J.; Hansen, A. K.; Sjorgren, J. M.; Barfod, K. K.
10.1101/2023.10.05.561007 — microbiology — Posted on 2023-10-05
3932 Phospholipid transport to the bacterial outer membrane through an envelope-spanning bridge
Isom, G.; Cooper, B. F.; Clark, R.; Kudhail, A.; Ekiert, D. C.; Bhabha, G.; Khalid, S.
10.1101/2023.10.05.561070 — microbiology — Posted on 2023-10-05
3936 Barcoded overexpression screens in gut Bacteroidales identify genes with new roles in carbon utilization and stress resistance
Huang, Y. Y.; Price, M. N.; Hung, A.; Gal-Oz, O.; Ho, D.; Carion, H.; Deutschbauer, A. M.; Arkin, A. P.
10.1101/2022.10.10.511384 — microbiology — Posted on 2023-10-05
3938 A murine model of Trypanosoma brucei-induced myocarditis and cardiac dysfunction
Crilly, N.; Zita, M. D.; Beaver, A.; Sysa-Shah, P.; Gabrielson, K.; Adamo, L.; Mugnier, M.
10.1101/2023.10.05.560950 — microbiology — Posted on 2023-10-05
3939 Fourth dose of Microneedle Array Patch of SARS-CoV-2 S1 Protein Subunit Vaccine Elicits Robust Long-lasting Humoral Responses in mice
Kim, E.; Shin, J.; Ferrari, A.; Huang, S.; An, E.; Han, D.; Khan, M. S.; Kenniston, T. W.; Cassaniti, I.; Baldanti, F.; Jeong, D.; Gambotto, A.
10.1101/2023.10.05.561047 — immunology — Posted on 2023-10-05
3941 Unveiling the antiviral capabilities of targeting Human Dihydroorotate Dehydrogenase against SARS-CoV-2
Purificacao, A.; Silva-Mendonca, S.; Cruz, L.; Sacramento, C.; Temerozo, J.; Fintelman-Rodrigues, N.; Freitas, C.; Godoi, B.; Vaidergorn, M.; Leite, J.; Alvarez, L.; Freitas, M.; Silva, M.; Martin, B.; Lopez, R.; Neves, B.; Costa, F.; Souza, T.; Emery, F.; Andrade, C.; Nonato, C.
10.1101/2023.10.04.560875 — biochemistry — Posted on 2023-10-05
3943 Method for Spatially Confined Stimulation by Retinal Scanning Displays: Are Blind Spots Really Blind?
Tavakoli, A.-V.; Omata, T.; Imamura, T.; Ogawa, R.; Iwasaki, M.; del Rio Salgado, J.; Rossi, I.; Hung, S.-M.; Wu, D.-A.; Shimojo, S.
10.1101/2023.10.03.560249 — neuroscience — Posted on 2023-10-05
3944 CellPLM: Pre-training of Cell Language Model Beyond Single Cells
Wen, H.; Tang, W.; Dai, X.; Ding, J.; Jin, W.; Xie, Y.; Tang, J.
10.1101/2023.10.03.560734 — bioinformatics — Posted on 2023-10-05
3950 Single-cell chromatin state transitions during epigenetic memory formation
Fujimori, T.; Rios-Martinez, C.; Thurm, A. R.; Hinks, M. M.; Doughty, B. R.; Sinha, J.; Le, D.; Hafner, A.; Greenleaf, W. J.; Boettiger, A. N.; Bintu, L.
10.1101/2023.10.03.560616 — genetics — Posted on 2023-10-05
3953 Association of leaf spectral variation with functional genetic variants
Li, C.; Czyz, E. A.; Ray, R.; Halitschke, R.; Baldwin, I. T.; Schaepman, M. E.; Schuman, M. C.
10.1101/2023.10.03.560760 — ecology — Posted on 2023-10-05
3955 Towards quantitative DNA Metabarcoding: A method to overcome PCR amplification bias
Moinard, S.; Piau, D.; Laporte, F.; Rioux, D.; Taberlet, P.; Coissac, E.; Gonindard-Melodelima, C.
10.1101/2023.10.03.560640 — ecology — Posted on 2023-10-05
3956 Immunologic changes are detectable in the peripheral blood transcriptome of clinically asymptomatic Chagas cardiomyopathy patients
Duque, C.; So, J.; Castro-Sesquen, Y. E.; DeToy, K.; Guarnizo, S. A. G.; Jahanbakhsh, F.; Machaca, E. M.; Miranda-Schaeubinger, M.; Chakravarti, I.; Cooper, V.; Schmidt, M. E.; Luigi, A.; Marcus, R.; Talaat, K. R.; Gilman, R. H.; Mugnier, M. R.; Chagas working group,
10.1101/2023.10.03.560680 — immunology — Posted on 2023-10-05
3959 Key determinants of the dual clamp/activator function of Complexin
Makke, M.; Pastor-Ruiz, A.; Yarzagaray, A.; Gaya, S.; Zimmer, M.; Frisch, W.; Bruns, D.
10.1101/2023.10.03.560784 — neuroscience — Posted on 2023-10-05
3960 The Role of Ryanodine Receptor 2 in Drug-Associated Learning
Barber, K. R.; Vizcarra, V. S.; Zilch, A.; Majuta, L.; Diezel, C. C.; Culver, O. P.; Hughes, B. W.; Taniguchi, M.; Streicher, J. M.; Vanderah, T. W.; Riegel, A. C.
10.1101/2023.10.03.560743 — neuroscience — Posted on 2023-10-05
3963 Chrysin directing an enhanced solubility through the formation of a supramolecular cyclodextrin-calixarene drug delivery system: a potential strategy in antifibrotic diabetes therapeutics
Hermenean, A.; Dossi, E.; Hamilton, A.; Trotta, M. C.; Russo, M.; Lepre, C. C.; Sajtos, C.; Rusznyak, A.; Varadi, J.; Bacskay, I.; DAmico, M.; Fenyvesi, F.
10.1101/2023.10.03.560552 — pharmacology and toxicology — Posted on 2023-10-05
3964 Pax Protein Depletion in Proximal Tubules Triggers Conserved Mechanisms of Resistance to Acute Ischemic Kidney Injury and Prevents Transition to Chronic Kidney Disease
Beamish, J. A.; Telang, A. C.; McElliott, M. C.; Al-Suraimi, A.; Chowdhury, M.; Ference-Salo, J. T.; Otto, E. A.; Menon, R.; Soofi, A.; Weinberg, J. M.; Patel, S. R.; Dressler, G. R.
10.1101/2023.10.03.559511 — pathology — Posted on 2023-10-05
3965 Segzoo: a turnkey system that summarizes genome annotations
Mendez, M.; Liu, Y.; Asenjo Ponce de Leon, M.; Hoffman, M. M.
10.1101/2023.10.03.559369 — bioinformatics — Posted on 2023-10-05
3970 Nphos: Database and Predictor of Protein N-phosphorylation
Ming-Xiao, Z.; Ruo-Fan, D.; Qiang, C.; Junhua, M.; Fulai, L.; Songsen, F.; Biling, H.; Yan, L.; Ji, Z.-L.; Yufen, Z.
10.1101/2023.10.03.559246 — bioinformatics — Posted on 2023-10-05
3971 Rummagene: Mining Gene Sets from Supporting Materials of PMC Publications
Clarke, D. J. B.; Marino, G. B.; Deng, E. Z.; Xie, Z.; Evangelista, J. E.; Ma'ayan, A.
10.1101/2023.10.03.560783 — bioinformatics — Posted on 2023-10-05
3972 Darwin's Overlooked Radiation: genomic evidence points to the early stages of a radiation in the Galapagos prickly pear cactus (Opuntia, Cactaceae)
Zapata, F.; Cerca, J.; McCarney, D.; Henriquez, C. L.; Tiamiyu, B. B.; McCormack, J.; Reckling, K. R.; Chaves, J. A.; Rivas-Torres, G.
10.1101/2023.10.03.560736 — evolutionary biology — Posted on 2023-10-05
3974 Consequences of directly- and indirectly-experienced heat stress in a mutagenic environment
Feugere, L.; Silva de Freitas, C.; Bates, A.; Storey, K. B.; Beltran-Alvarez, P.; Valero, K. C. W.
10.1101/2023.10.03.560724 — ecology — Posted on 2023-10-05
3975 Palatal segment contributions to midfacial growth in three inbred mouse strains
Welsh, I. C.; Feiler, M.; Lipman, D.; Mormile, I.; Hansen, K.; Percival, C. J. C.
10.1101/2023.10.03.560703 — developmental biology — Posted on 2023-10-05
3976 Spatial transcriptomics of peach and nectarine elucidates the mechanism underlying fruit trichome development
Zhao, Z.; Cao, K.; Qin, A.; Liu, Z.; Guan, L.; Sun, S.; Liu, H.; Zhou, Y.; Yang, J.; Liu, Y.; Hu, M.; Ninkuu, V.; Sun, X.; Wang, L.
10.1101/2023.10.03.560746 — developmental biology — Posted on 2023-10-05
3977 Synovial macrophage diversity and activation of M-CSF signaling in post-traumatic osteoarthritis
Knights, A. J.; Farrell, E. C.; Ellis, O. M.; Song, M. J.; Appleton, C. T.; Maerz, T.
10.1101/2023.10.03.559514 — immunology — Posted on 2023-10-05
3978 Type I IFN signaling in the absence of IRGM1 promotes M. tuberculosis replication in immune cells by suppressing T cell responses
Naik, S. K.; McNehlan, M. E.; Mreyoud, Y.; Kinsella, R. L.; Smirnov, A.; Chowdhury, C. S.; McKee, S. R.; Dubey, N.; Woodson, R.; Kreamalmeyer, D.; Stallings, C. L.
10.1101/2023.10.03.560720 — immunology — Posted on 2023-10-05
3979 Passive exposure to task-relevant stimuli enhances categorization learning
Schmid, C.; Haziq, M.; Baese-Berk, M. M.; Murray, J. M.; Jaramillo, S.
10.1101/2023.04.04.535463 — neuroscience — Posted on 2023-10-05
3980 Mice require proprioception to establish long-term visuospatial memory.
Goldberg, M. E.; Rutler, O.; Bruno, R. M.; Park, J. M.; Persaud, S.; Kosmidis, S.; Hirano, N.
10.1101/2023.10.03.560558 — neuroscience — Posted on 2023-10-05
3986 Mitosis exit followed by death in interphase prevents the development of polyploid giant cancer cells.
Vicente, J. J.; Khan, K.; Tillinghast, G.; McFaline-Figueroa, J. L.; Sancak, Y.; Stella, N.
10.1101/2023.08.31.555795 — cell biology — Posted on 2023-10-05
3987 Hippocampal Interneuronal Dysfunction and Hyperexcitability in a Porcine Model of Concussion
Cottone, C.; Ulyanova, A. V.; Cottone, C.; Maheshwari, N.; Grovola, M. R.; Fruchet, O. E.; Alamar, J.; Koch, P. F.; Johnson, V. E.; Cullen, D. K.; Wolf, J. A.
10.1101/2022.03.08.483543 — neuroscience — Posted on 2023-10-05
3988 Non-Consummatory Behavior Signals Predict Aversion-Resistant Alcohol Drinking in Head-Fixed Mice
Timme, N.; Ardinger, C.; Weir, S. D. C.; Zelaya-Escobar, R.; Kruger, R.; Lapish, C. C.
10.1101/2023.06.20.545767 — neuroscience — Posted on 2023-10-05
3989 An Event-Related Potential Study of Onset Primacy in Visual Change Detection
Van Pelt, J.; Lowe, B. G.; Robinson, J. E.; Donaldson, M. J.; Johnston, P.; Yamamoto, N.
10.1101/539932 — neuroscience — Posted on 2023-10-05
3990 Maize integrates light and volatile cues from neighboring plants into stronger volatile emissions
Escobar-Bravo, R.; Schimmel, B. C.; Zhang, Y.; Wang, L.; Robert, C. A.; Glauser, G.; Ballare, C. L.; Erb, M.
10.1101/2022.09.12.507519 — plant biology — Posted on 2023-10-05
3991 The three-dimensionally articulated oral apparatus of a Devonian heterostracan sheds light on feeding in Palaeozoic jawless fishes
Dearden, R. P.; Jones, A.; Giles, S.; Lanzetti, A.; Grohganz, M.; Johanson, Z.; Lautenschlager, S.; Randle, E.; Donoghue, P.; Sansom, I. J.
10.1101/2023.08.22.554283 — paleontology — Posted on 2023-10-05
3994 Microinterfaces in bicontinuous hydrogels guide rapid 3D cell migration
Xu, K. L.; Caprio, N. d.; Fallahi, H.; Dehgany, M.; Davidson, M. D.; Cheung, B. C.; Laforest, L.; Wu, M.; Shenoy, V.; Han, L.; Mauck, R. L.; Burdick, J. A.
10.1101/2023.09.28.559609 — bioengineering — Posted on 2023-10-05
3995 Genetic and environmental contributions to ancestry differences in gene expression in the human brain
Benjamin, K. J.; Chen, Q.; Eagles, N. J.; Huuki-Myers, L. A.; Collado-Torres, L.; Stolz, J. M.; Pertea, G.; Shin, J. H.; Paquola, A. C.; Hyde, T. M.; Kleinman, J. E.; Jaffe, A. E.; Han, S.; Weinberger, D. R.
10.1101/2023.03.28.534458 — genetics — Posted on 2023-10-05
3998 Alterations in DNA 5-hydroxymethylation Patterns in the Hippocampus of an Experimental Model of Refractory Epilepsy
Bahabry, R.; Hauser, R. M.; Sanchez, R.; Sint Jago, S.; Ianov, L.; Stuckey, R.; Parrish, R.; Ver Hoef, L.; Lubin, F.
10.1101/2023.10.03.560698 — neuroscience — Posted on 2023-10-05
4000 BunDLe-Net: Neuronal Manifold Learning Meets Behaviour
Kumar, A.; Gilra, A.; Gonzalez-Soto, M.; Meunier, A.; Grosse-Wentrup, M.
10.1101/2023.08.08.551978 — neuroscience — Posted on 2023-10-05
4004 Tailored mass spectral data exploration using the specXplore interactive dashboard
Mildau, K.; Ehlers, H.; Oesterle, I.; Pristner, M.; Warth, B.; Doppler, M.; Bueschl, C.; Zanghellini, J.; van der Hooft, J. J. J.
10.1101/2023.10.03.560677 — bioinformatics — Posted on 2023-10-05
4008 Predictable sequential structure enhances auditory sensitivity in clinical audiograms
Marin, N.; Gerenton, G.; Jean, H.; Paraouty, N.; Lazard, D. S.; Arnal, L. H.; Doelling, K. B.
10.1101/2023.10.03.560670 — animal behavior and cognition — Posted on 2023-10-05
4017 Development of a mutant aerosolized ACE2 that neutralizes SARS-CoV-2 in vivo
Kober, D. L.; Caballero Van Dyke, M. C.; Eitson, J. L.; Boys, I. N.; McDougal, M. B.; Rosenbaum, D.; Schoggins, J. W.
10.1101/2023.09.26.559550 — microbiology — Posted on 2023-10-05
4022 Exploiting O-GlcNAc Transferase promiscuity to dissect site-specific O-GlcNAcylation
Mitchell, C. W.; Bartual, S. G.; Ferenbach, A. T.; Scavenius, C.; van Aalten, D. M. F.
10.1101/2023.07.31.551258 — biochemistry — Posted on 2023-10-05
4024 Divergent downstream biosynthetic pathways are supported by L-cysteine synthases of Mycobacterium tuberculosis
Khan, M.; Hunt, D. M.; Singha, B.; Kapoor, Y.; Singh, N.; Prasad, D. V. S.; Dharmarajan, S.; Sowpati, D. T.; de Carvalho, L.; Nandicoori, V. K.
10.1101/2023.10.03.560673 — microbiology — Posted on 2023-10-05
4025 Immediate effects of light on circadian eclosion and locomotor activity depend on distinct sensory input pathways
Bidell, D.; Feige, N.-D.; Triphan, T.; Mueller, C.; Pauls, D.; Helfrich-Förster, C.; Selcho, M.
10.1101/2023.04.21.537872 — neuroscience — Posted on 2023-10-05
4026 Genomic profiling and pre-clinical modelling of breast cancer leptomeningeal metastasis reveals acquisition of a lobular-like phenotype
Fitzpatrick, A.; Iravani, M.; Mills, A.; Vicente, D.; Alaguthurai, T.; Roxanis, I.; Turner, N. C.; Haider, S.; Tutt, A. N. J.; Isacke, C.
10.1101/2023.01.20.524591 — cancer biology — Posted on 2023-10-05
4027 Wide Transition-State Ensemble as Key Component for Enzyme Catalysis
Jara, G.; Pontiggia, F.; Otten, R.; Agafonov, R. V.; Marti, M. A.; Kern, D.
10.1101/2023.10.03.560706 — biophysics — Posted on 2023-10-05
4028 Evolution towards simplicity in bacterial small heat shock protein system
Karas, P.; Kochanowicz, K.; Pitek, M.; Domanski, P.; Obuchowski, I.; Tomiczek, B.; Liberek, K.
10.1101/2023.05.18.541272 — biochemistry — Posted on 2023-10-05
4030 7,8-Dihydroxyflavone is a direct inhibitor of pyridoxal phosphatase
Zink, C.; Witzinger, L.; Keller, A.; Hadamek, K.; Bothe, S.; Neuenschwander, M.; Villmann, C.; von Kries, J. P.; Schindelin, H.; Jeanclos, E.; Gohla, A.
10.1101/2023.10.04.560852 — biochemistry — Posted on 2023-10-05
4031 Immune activation state modulates retrieval of infant engrams
Power, S. D.; Stewart, E.; Zielke, L.; Byrne, E. P.; Ortega-de San Luis, C.; Lynch, L.; Ryan, T. J.
10.1101/2022.04.24.488172 — neuroscience — Posted on 2023-10-05
4032 GLUD1 dictates muscle stem cell differentiation by controlling mitochondrial glutamate levels
Soro-Arnaiz, I.; Cherkaoui, S.; Fitzgerald, G.; Zhang, J.; Gilardoni, P.; Gosh, A.; Bar-Nur, O.; Masschelein, E.; Maechler, P.; Zamboni, N.; Poms, M.; Cremonesi, A.; Garcia-Canaveras, J. C.; De Bock, K.; Morscher, R. J.
10.1101/2023.10.04.560525 — cell biology — Posted on 2023-10-05
4038 Ancestral genetic components are consistently associated with the complex trait landscape in European biobanks
Pankratov, V.; Mezzavilla, M.; Aneli, S.; Fusco, D.; Wilson, J. F.; Metspalu, M.; Provero, P.; Pagani, L.; Marnetto, D.
10.1101/2023.10.04.560881 — genomics — Posted on 2023-10-05
4041 A human-specific microRNA controls the timing of excitatory synaptogenesis
Soutschek, M.; LoBianco, A.; Galkin, S.; Wuest, T.; Colameo, D.; Germade, T.; Gross, F.; von Ziegler, L.; Bohacek, J.; Germain, P.-L.; Winterer, J.; Kleele, T.; Schratt, G.
10.1101/2023.10.04.560889 — neuroscience — Posted on 2023-10-05
4043 Axonopathy and altered synaptic development in early hippocampal epileptogenesis of Dravet syndrome
Layer, N.; Müller, P.; Ayash, M.; Pfeiffer, F.; Saile, M.; Klopfer, F.; Iavarone, S.; Santuy, A.; Fallier-Becker, P.; Hedrich, U. B. S.; Lerche, H.; Koch, H.; Wuttke, T. V.
10.1101/2023.10.04.560735 — neuroscience — Posted on 2023-10-05
4044 Structure-Function Coupling in Highly Sampled Individual Brains
Rajesh, A.; Seider, N. A.; Newbold, D. J.; Adeyemo, B.; Marek, S.; Greene, D. J.; Snyder, A. Z.; Shimony, J. S.; Laumann, T. O.; Dosenbach, N. U. F.; Gordon, E. M.
10.1101/2023.10.04.560909 — neuroscience — Posted on 2023-10-05
4045 Conjoint specification of action by neocortex and striatum
Park, J.; Polidoro, P.; Fortunato, C.; Arnold, J. A.; Mensh, B. D.; Gallego, J. A.; Dudman, J. T.
10.1101/2023.10.04.560957 — neuroscience — Posted on 2023-10-05
4046 Aberrant pace of cortical neuron development in brain organoids from patients with 22q11.2 deletion syndrome and schizophrenia
Sneha, R. B.; Brundu, F.; Chen, Y.; Sun, Y.; Zhu, H.; Shprintzen, R. J.; Tomer, R.; Rabadan, R.; Leong, K. W.; Markx, S.; Xu, B.; Gogos, J. A.
10.1101/2023.10.04.557612 — neuroscience — Posted on 2023-10-05
4047 A novel, tissue-associated and vertically transmitted bacterial symbiont in the coral Pocillopora acuta
Maire, J.; Tsang Min Ching, S. J.; Damjanovic, K.; Epstein, H. E.; Judd, L. M.; Blackall, L. L.; van Oppen, M. J. H.
10.1101/2023.09.14.557667 — microbiology — Posted on 2023-10-04
4049 A genome-wide CRISPR screen supported by human genetics identifies the TNRC18 gene locus as a novel regulator of inflammatory signaling
Rahimov, F.; Ghosh, S.; Petiwala, S.; Schmidt, M.; Nyamugenda, E.; Tam, J.; Verduzco, D.; Singh, S.; Avram, V.; Modi, A.; Espinoza, C. A.; Lu, C.; Wang, J.; Keller, A.; Macoritto, M.; Mahi, N. A.; Anton, T.; Chung, N.; Flister, M. J.; Katlinski, K. V.; Biswas, A.; den Hollander, A. I.; Waring, J. F.; Stender, J. D.
10.1101/2023.10.04.560902 — genomics — Posted on 2023-10-04
4050 The carbapenem inoculum effect provides insight into the molecular mechanisms underlying carbapenem resistance in Enterobacterales
Cartagena, A. J.; Taylor, K. L.; Smith, J. T.; Manson, A. L.; Earl, A. M.; Pierce, V. M.; Bhattacharyya, R. P.
10.1101/2023.05.23.541813 — microbiology — Posted on 2023-10-04
4051 A potent MAPK13-14 inhibitor prevents airway inflammation and mucus production
Keeler, S. P.; Wu, K.; Zhang, Y.; Mao, D.; Li, M.; Iberg, C. A.; Austin, S. R.; Glaser, S. A.; Yantis, J.; Podgorny, S.; Brody, S. L.; Chartock, J. R.; Han, Z.; Byers, D. E.; Romero, A. G.; Holtzman, M. J.
10.1101/2023.05.26.542451 — immunology — Posted on 2023-10-04
4052 Fyn-mediated phosphorylation of Menin disrupts telomere maintenance in stem cells
Paul, S.; McCourt, P. M.; Le, L. T. M.; Ryu, J.; Czaja, W.; Bode, A. M.; Contreras-Galindo, R.; Dong, Z.
10.1101/2023.10.04.560876 — molecular biology — Posted on 2023-10-04
4054 Single-molecule analysis reveals TDG exhibits multiple modes of linear diffusion to process 5-formylcytosine.
Schnable, B. L.; Schaich, M. A.; Roginskaya, V.; Leary, L. P.; Weaver, T. M.; Freudenthal, B. D.; Drohat, A. C.; Van Houten, B.
10.1101/2023.10.04.560925 — biophysics — Posted on 2023-10-04
4055 mtx-COBRA: Subcellular localization prediction for bacterial proteins
Arora, I.; Kummer, A.; Zhou, H.; Gadjeva, M.; Ma, E.; Chuang, G.-Y.; Ong, E.
10.1101/2023.10.04.560913 — bioinformatics — Posted on 2023-10-04
4057 Transcription factor stoichiometry, motif affinity and syntax regulate single-cell chromatin dynamics during fibroblast reprogramming to pluripotency
Nair, S.; Ameen, M.; Sundaram, L.; Pampari, A.; Schreiber, J.; Balsubramani, A.; Wang, Y. X.; Burns, D.; Blau, H. M.; Karakikes, I.; Wang, K. C.; Kundaje, A.
10.1101/2023.10.04.560808 — genetics — Posted on 2023-10-04
4059 Investigations on Antarctic fish IgM drives the generation of an engineered mAb by CRISPR/Cas9
Coscia, M. R.; Ametrano, A.; Miranda, B.; Moretta, R.; Dardano, P.; De Stefano, L.; Oreste, U.
10.1101/2023.10.04.560855 — molecular biology — Posted on 2023-10-04
4062 Bacteriophage in combination with ciprofloxacin against Pseudomonas aeruginosa infections in diabetic foot ulcer patients
Liu, S.; Goonetilleke, S.; Hon, K.; Burdon, I.; Bouras, G.; Mcmillan, N.; Psaltis, A.; Wormald, P.; Fitridge, R.; Vreugde, S.
10.1101/2023.10.03.560795 — microbiology — Posted on 2023-10-04
4063 High diversity, abundance and expression of hydrogenases in groundwater
Li, S.; Mosier, D.; Kouris, A.; Humez, P.; Mayer, B.; Strous, M.; Diao, M.
10.1101/2023.10.03.560699 — microbiology — Posted on 2023-10-04
4065 Analysis of the Diverse Antigenic Landscape of the Malaria Invasion Protein RH5 Identifies a Potent Vaccine-Induced Human Public Antibody Clonotype
Barrett, J. R.; Pipini, D.; Wright, N. D.; Cooper, A. J. R.; Gorini, G.; Quinkert, D.; Lias, A. M.; Davies, H.; Rigby, C.; Aleshnick, M.; Williams, B. G.; Bradshaw, W. J.; Paterson, N. G.; Martinson, T.; Kirtley, P.; Picard, L.; Wiggins, C. D.; Donnellan, F. R.; King, L. D. W.; Wang, L. T.; Popplewell, J. F.; Silk, S. E.; Swain, J. d. R.; Skinner, K.; Kotraiah, V.; Noe, A. R.; MacGill, R. S.; King, C. R.; Birkett, A. J.; Soisson, L. A.; Minassian, A. M.; Lauffenburger, D. A.; Miura, K.; Long, C. A.; Wilder, B. K.; Koekemoer, L.; Tan, J.; Nielsen, C. M.; McHugh, K.; Draper, S. J.
10.1101/2023.10.04.560576 — immunology — Posted on 2023-10-04
4072 mRNA N1-2'O-methylation by CMTR1 affects NVL2 mRNA splicing
Wolter, S.; Hennig, T.; Wallerath, C.; Schlee-Guimaraes, T. M.; Kirchhoff, A.; Urban, C.; Piras, A.; Stukalov, A.; Juranek, S.; Engelke, M.; Boehm, V.; Gehring, N. H.; Hartmann, G.; Pichlmair, A.; Friedel, C. C.; Doelken, L.; Schlee, M.
10.1101/2023.09.28.560047 — molecular biology — Posted on 2023-10-04
4073 Group A Streptococcus remains viable inside fibrin clots and gains access to human plasminogen for subsequent fibrinolysis and dissemination
Vu, H. M.; Liang, Z.; Bao, Y.-J.; Carles, P. G.; Keane, J. C.; Cerney, M. G.; Dahnke, C. N.; Flores-Mireles, A. L.; Ploplis, V. A.; Castellino, F. J.; Lee, S. W.
10.1101/2023.10.04.560727 — microbiology — Posted on 2023-10-04
4074 Establishment and comparative genomics of a high-quality collection of mosquito-associated bacterial isolates -- MosAIC (Mosquito-Associated Isolate Collection)
Foo, A.; Brettell, L. E.; Nichols, H. L.; 2022 UW-Madison Capstone in Microbiology Students, ; Medina Munoz, M.; Lysne, J.; Dhokiya, V.; Hoque, A. F.; Brackney, D. E.; Caragata, E. P.; Hutchinson, M.; Jacobs-Lorena, M.; Lampe, D. J.; Martin, E.; Valiente Moro, C.; Povelones, M.; Short, S. M.; Steven, B.; Xu, J.; Paustian, T. D.; Rondon, M. R.; Hughes, G. L.; Coon, K. L.; Heinz, E.
10.1101/2023.10.04.560816 — microbiology — Posted on 2023-10-04
4075 YlaN is an iron(II) binding protein that functions to relieve Fur-mediated repression of gene expression in Staphylococcus aureus
Boyd, J. M.; esquilin-lebron, K. M.; Campbell, C. J.; Ryan Kaler, K. M.; Norambuena, J.; Foley, M. E.; Stephens, T. G.; Rios, G.; Mereddy, G.; Zheng, V.; Bovermann, H.; Kim, J.; Kulczyk, A. W.; Yang, J. H.; Greco, T. M.; Cristea, I. M.; Carabetta, V. J.; Beavers, W. N.; Bhattacharya, D.; Skaar, E. P.; Parker, D.; Carroll, R. K.; Stemmler, T. L.
10.1101/2023.10.03.560778 — microbiology — Posted on 2023-10-04
4076 A polarized cell system amenable to subcellular resolution imaging of influenza virus infection
Naffakh, N.; Brault, J.-B.; Thouvenot, C.; Cannata-Serio, M.; Paisant, S.; Fernandez, J.; Geny, D.; Danglot, L.; Mallet, A.
10.1101/2023.10.03.560780 — microbiology — Posted on 2023-10-04
4078 Anchoring of parasitic plasmids to inactive regions of eukaryotic chromosomes through nucleosome signal
Girard, F.; Even, A.; Thierry, A.; Ruault, M.; Meneu, L.; Adiba, S.; Taddei, A.; Koszul, R.; Cournac, A.
10.1101/2023.10.04.558402 — genomics — Posted on 2023-10-04
4079 SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia
Luo, Y.-W.; Zhou, J.-P.; Ji, H.; Zheng, A.; Wang, X.; Dai, Z.; Luo, Z.; Cao, F.; Wang, X.-Y.; Bai, Y.; Chen, D.; Chen, Y.; Wang, Q.; Yang, Y.; Zhang, X.; Chiu, S.; Huang, A.-L.; Tang, K.-F.
10.1101/2023.10.03.560426 — microbiology — Posted on 2023-10-04
4080 mRNA vaccines encoding membrane-anchored receptor-binding domains of SARS-CoV-2 mutants induce strong humoral responses and can overcome immune imprinting
Al-Wassiti, H. A.; Fabb, S. A.; Grimley, S. L.; Kochappan, R.; Ho, J. K.; Wong, C. Y.; Tan, C. W.; Payne, T. J.; Takanashi, A.; Sicilia, H.; Teo, S. L. Y.; McAuley, J. L.; Ellenberg, P.; Cooney, J. P.; Davidson, K. C.; Bowen, R.; Pellegrini, M.; Rockman, S.; Godfrey, D. I.; Nolan, T. M.; Wang, L.-F.; Deliyannis, G.; Purcell, D. F. J.; Pouton, C. W.
10.1101/2023.10.04.560777 — immunology — Posted on 2023-10-04
4085 eNODAL: an experimentally guided nutriomics data clustering method to unravel complex drug-diet interactions
Xu, X.; Senior, A. M.; Le Couteur, D. G.; Cogger, V. C.; Raubenheimer, D.; James, D. E.; Parker, B.; Simpson, S. J.; Muller, S.; Yang, J. Y. H.
10.1101/2023.10.03.560662 — bioinformatics — Posted on 2023-10-04
4087 Hidden in the sand: phylogenomics unravel an unexpected evolutionary history on the desert-adapted vipers of the genus Cerastes
Mochales-Riano, G.; Burriel-Carranza, B.; Barros, M. I.; Velo-Anton, G.; Talavera, A.; Spilani, L.; Tejero-Cicuendez, H.; Andre-Crochet, P.; Piris, A.; Garcia-Cardenete, L.; Busais, S.; Els, J.; Shobrak, M.; Carlos-Brito, J.; Smid, J.; Carranza, S.; Martinez-Freiria, F.
10.1101/2023.10.03.560686 — genomics — Posted on 2023-10-04
4088 Post-acute immunological and behavioral sequelae in mice after Omicron infection
Ma, T.; Suryawanshi, R. K.; Miller, S. R.; Ly, K. K.; Thomas, R.; Elphick, N.; Yin, K.; Luo, X.; Kaliss, N.; Chen, I. P.; Montano, M.; Sreekumar, B.; Standker, L.; Munch, J.; Damron, F. H.; Palop, J. J.; Ott, M.; Roan, N. R.
10.1101/2023.06.05.543758 — microbiology — Posted on 2023-10-04
4089 CaBLAM! A high-contrast bioluminescent Ca2+ indicator derived from an engineered Oplophorus gracilirostris luciferase
Lambert, G. G.; Crespo, E. L.; Murphy, J.; Boassa, D.; Luong, S.; Celinskis, D.; Venn, S.; Hu, J.; Sprecher, B.; Tree, M. O.; Orcutt, R.; Heydari, D.; Bell, A. B.; Torreblanca-Zanca, A.; Hakimi, A.; Lipscombe, D.; Moore, C. I.; Hochgeschwender, U.; Shaner, N. C.
10.1101/2023.06.25.546478 — neuroscience — Posted on 2023-10-04
4090 Human brain state dynamics reflect individual neuro-phenotypes
Lee, K.; Ji, J. L.; Fonteneau, C.; Berkovitch, L.; Rahmati, M.; Pan, L.; Repovs, G.; Krystal, J. H.; Murray, J. D.; Anticevic, A.
10.1101/2023.09.18.557763 — neuroscience — Posted on 2023-10-04
4091 Ancient origin of the rod bipolar cell pathway in the vertebrate retina
Hellevik, A. M.; Mardoum, P.; Hahn, J.; Kolsch, Y.; D'Orazi, F. D.; Suzuki, S. C.; Godinho, L.; Lawrence, O.; Rieke, F.; Shekhar, K.; Sanes, J. R.; Baier, H.; Baden, T.; Wong, R. O.; Yoshimatsu, T.
10.1101/2023.09.12.557433 — neuroscience — Posted on 2023-10-04
4093 Event-related modulation of alpha rhythm explains the auditory P300 evoked response in EEG
Studenova, A. A.; Forster, C.; Engemann, D. A.; Hensch, T.; Sander, C.; Mauche, N.; Hegerl, U.; Loeffler, M.; Villringer, A.; Nikulin, V. V.
10.1101/2023.02.20.529191 — neuroscience — Posted on 2023-10-04
4099 Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors
Nigam, A.; Hurley, M. F. D.; Li, F.; Konkolova, E.; Klima, M.; Trylcova, J.; Pollice, R.; Cınaroglu, S. S.; Levin-Konigsberg, R.; Handjaya, J.; Schapira, M.; Chau, I.; Perveen, S.; Ng, H.-L.; Kaniskan, H. U.; Han, Y.; Singh, S.; Gorgulla, C.; Kundaje, A.; Jin, J.; Voelz, V. A.; Weber, J.; Nencka, R.; Boura, E.; Vedadi, M.; Aspuru-Guzik, A.
10.1101/2023.10.03.560722 — biochemistry — Posted on 2023-10-04
4101 Diverse prey capture strategies in teleost larvae
Mearns, D. S.; Hunt, S. A.; Schneider, M. W.; Parker, A. V.; Stemmer, M.; Baier, H.
10.1101/2023.10.03.560453 — animal behavior and cognition — Posted on 2023-10-04
4102 Endogenous retroviruses mediate transcriptional rewiring in response to oncogenic signaling in colorectal cancer
Ivancevic, A.; Simpson, D. M.; Joyner, O. M.; Bagby, S. M.; Nguyen, L. L.; Bitler, B. G.; Pitts, T. M.; Chuong, E. B.
10.1101/2021.10.28.466196 — genomics — Posted on 2023-10-04
4104 The impact of common variants on gene expression in the human brain: from RNA to protein to schizophrenia risk
Liang, Q.; Jiang, Y.; Shieh, A. W.; Zhou, D.; Chen, R.; Wang, F.; Xu, M.; Wang, X.; Pinto, D.; Wang, Y.; Cheng, L.; Vadukapuram, R.; Zhang, C.; Grennan, K.; Giase, G.; The PsychENCODE Consortium, ; White, K. P.; Peng, J.; Li, B.; Liu, C.; Chen, C.; Wang, S. H.
10.1101/2023.06.04.543603 — genetics — Posted on 2023-10-04
4105 Fe-TAMLs as a new class of small molecule peroxidase probes for correlated light and electron microscopy
Adams, S. R.; Mackey, M. R.; Ramachandra, R.; Deerinck, T. J.; Castillon, G. A.; Phan, S.; Hu, J.; Boassa, D.; Ngo, J. T.; Ellisman, M. H.
10.1101/2023.08.25.554352 — cell biology — Posted on 2023-10-04
4106 Developmental conversion of thymocyte-attracting cells into self-antigen-displaying cells in embryonic thymus medulla epithelium
Ohigashi, I.; White, A.; Yang, M.-T.; Fujimori, S.; Tanaka, Y.; Jacques, A.; Kiyonari, H.; Matsushita, Y.; Turan, S.; Kelly, M. C.; Anderson, G.; Takahama, Y.
10.1101/2023.10.03.560657 — immunology — Posted on 2023-10-04
4107 IL-4 downregulates BCL6 to promote memory B cell selection in germinal centers
Shehata, L.; Thouvenel, C. D.; Hondowicz, B. D.; Pew, L. A.; Rawlings, D. J.; Choi, J.; Pepper, M.
10.1101/2023.01.26.525749 — immunology — Posted on 2023-10-04
4108 HOTARU: Automatic sorting system for large scale calcium imaging data
Takekawa, T.; Nomoto, M.; Asai, H.; Ohkawa, N.; Okubo-Suzuki, R.; Ghandour, K.; Sato, M.; Ohkura, M.; Nakai, J.; Muramatsu, S.-i.; Hayashi, Y.; Inokuchi, K.; Fukai, T.
10.1101/2022.04.05.487077 — neuroscience — Posted on 2023-10-04
4110 Backbone extension acyl rearrangements enable cellular synthesis of proteins with internal β2-peptide linkages
Roe, L.; Schissel, C. K.; Dover, T. L.; Shah, B.; Hamlish, N. X.; Zheng, S.; Dilworth, D. A.; Wong, N.; Zhang, Z.; Chatterjee, A.; Francis, M. B.; Miller, S. J.; Schepartz, A.
10.1101/2023.10.03.560714 — synthetic biology — Posted on 2023-10-04
4111 Leveraging inter-individual transcriptional correlation structure to infer discrete signaling mechanisms across metabolic tissues
Zhou, M.; Van, C.; Molendijk, J.; Chang, I. Y.-Y.; Johnson, C.; Velez, L. M.; Yeo, R.; Bae, H.; Le, J.; Larson, N.; Pulido, R.; Nascimento-Filho, C.; Hevener, A. L.; Sparks, L.; Justice, J.; Kershaw, E.; Marazzi, I.; Pannunzio, N.; Nicholas, D.; Parker, B. L.; Jang, C.; Masri, S.; Seldin, M. M.
10.1101/2023.05.10.540142 — physiology — Posted on 2023-10-04
4112 Tumor removal limits prostate cancer cell dissemination in bone and osteoblasts induce cancer cell dormancy through focal adhesion kinase
Liu, R.; Su, S.; Xing, J.; Liu, K.; Zhao, Y.; Stangis, M.; Jacho, D. P.; Yildirim-Ayan, E. D.; Gatto-Weis, C. M.; Chen, B.; Li, X.
10.1101/2022.09.02.506436 — cancer biology — Posted on 2023-10-04
4115 Postglacial genomes from foragers across Northern Eurasia reveal prehistoric mobility associated with the spread of the Uralic and Yeniseian languages
Zeng, T. C.; Vyazov, L. A.; Kim, A.; Flegontov, P.; Sirak, K.; Maier, R.; Lazaridis, I.; Akbari, A.; Frachetti, M.; Tishkin, A. A.; Ryabogina, N. E.; Agapov, S. A.; Agapov, D. S.; Alekseev, A. N.; Boeskorov, G. G.; Chizhevsky, A. A.; Derevianko, A. P.; Dyakonov, V. M.; Enshin, D. N.; Fribus, A. V.; Frolov, Y. V.; Grushin, S. P.; Khokhlov, A. A.; Kitov, E. P.; Kosintsev, P.; Kovtun, I. V.; Kiryushin, K. Y.; Kiryushin, Y. F.; Makarov, N. P.; Morozov, V. V.; Nikolaev, E. N.; Rykun, M. P.; Savenkova, T. M.; Shchelchkova, M. V.; Skochina, S. N.; Shirokov, V.; Sherstobitova, O. S.; Slepchenko, S. M.
10.1101/2023.10.01.560332 — genomics — Posted on 2023-10-04
4116 Genetic barriers more than ecological adaptations shaped Serratia marcescens diversity
Sterzi, L.; Nodari, R.; Di Marco, F.; Ferrando, M. L.; Saluzzo, F.; Spitaleri, A.; Allahverdi, H.; Papaleo, S.; Panelli, S.; Rimoldi, S. G.; Batisti Biffignandi, G.; Corbella, M.; Cavallero, A.; Prati, P.; Farina, C.; Cirillo, D. M.; Zuccotti, G.; Bandi, C.; Comandatore, F.
10.1101/2023.07.14.548978 — evolutionary biology — Posted on 2023-10-04
4118 A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system
Costacurta, F.; Dodaro, A.; Bante, D.; Schoeppe, H.; Sprenger, B.; Moghadasi, S. A.; Fleischmann, J.; Pavan, M.; Bassani, D.; Menin, S.; Rauch, S.; Krismer, L.; Sauerwein, A.; Heberle, A.; Rabensteiner, T.; Ho, J.; Harris, R. S.; Stefan, E.; Schneider, R.; Kaserer, T.; Moro, S.; von Laer, D.; Heilmann, E.
10.1101/2023.09.22.558628 — microbiology — Posted on 2023-10-04
4119 Human cortex development is shaped by molecular and cellular brain systems
Lotter, L. D.; Saberi, A.; Hansen, J. Y.; Misic, B.; Paquola, C.; Barker, G. J.; Bokde, A. L. W.; Desrivieres, S.; Flor, H.; Grigis, A.; Garavan, H.; Gowland, P.; Heinz, A.; Bruehl, R.; Martinot, J.-L.; Paillere, M.-L.; Artiges, E.; Papadopoulos Orfanos, D.; Paus, T.; Poustka, L.; Hohmann, S.; Froehner, J. H.; Smolka, M. N.; Vaidya, N.; Walter, H.; Whelan, R.; Schumann, G.; IMAGEN Consortium, ; Nees, F.; Banaschewski, T.; Eickhoff, S. B.; Dukart, J.
10.1101/2023.05.05.539537 — neuroscience — Posted on 2023-10-04
4120 Whole-cortex in situ sequencing reveals peripheral input-dependent cell type-defined area identity
Chen, X.; Fischer, S.; Rue, M. C.; Zhang, A.; Mukherjee, D.; Kanold, P. O.; Gillis, J.; Zador, A.
10.1101/2022.11.06.515380 — neuroscience — Posted on 2023-10-04
4121 Stand age diversity weakens forests sensitivity to climate change
Vangi, E.; Dalmonech, D.; Cioccolo, E.; Marano, G.; Bianchini, L.; Puchi, P.; Grieco, E.; Colantoni, A.; Chirici, G.; Collalti, A.
10.1101/2023.07.12.548709 — plant biology — Posted on 2023-10-04
4122 Uterine secretome initiates growth of gynecologic tissues in ectopic locations.
Sunde, J.; Wasickanin, M.; Katz, T. A.; Bidadi, S.; O'Neil, D.; Burney, R. O.; Pennington, K. A.
10.1101/2023.10.04.560850 — cancer biology — Posted on 2023-10-04
4125 Development of a high dimensional imaging mass cytometry panel to investigate spatial organization of tissue microenvironment in formalin-fixed archival clinical tissues
Tornaas, S.; Kleftogiannis, D.; Fromreide, S.; Ytre-Hauge Smeland, H.; Aarstad, H. J.; Karsten Vintermyr, O.; Andreas Akslen, L.; Elena Costea, D.; Dongre, H.
10.1101/2022.05.12.491175 — cancer biology — Posted on 2023-10-04
4130 The longest intron rule
Dvorak, P.; Hlavac, V.; Hanicinec, V.; Rao, B. H.; Soucek, P.
10.1101/2023.10.02.560625 — genomics — Posted on 2023-10-04
4132 WASP facilitates tumor mechanosensitivity in T lymphocytes
Mandal, S.; Melo, M. B.; Gordiichuk, P.; Acharya, S.; Poh, Y.-C.; Li, N.; Aung, A.; Dane, E.; Irvine, D. J.; Kumari, S.
10.1101/2023.10.02.560434 — immunology — Posted on 2023-10-04
4133 Precise cortical contributions to feedback sensorimotor control during reactive balance
Boebinger, S.; Payne, A.; Martino, G.; Kerr, K.; Mirdamadi, J.; McKay, J. L.; Borich, M.; Ting, L.
10.1101/2023.10.02.560626 — neuroscience — Posted on 2023-10-04
4135 DIRECTED GRAPH THEORY FOR THE ANALYSIS OF BIOLOGICAL REGULATORY NETWORKS
Takane, M.; Bernal-Gonzalez, S.; Mauro-Moreno, J.; Garcia-Lopez, G.; Mendez-Ambrosio, B.; F. De-Miguel, F.
10.1101/2023.10.02.560622 — neuroscience — Posted on 2023-10-04
4136 Targeted inhibition of BET proteins in HPV-16 associated head and neck squamous cell carcinoma reveals heterogeneous transcription response
Rao, A.; Ni, Z.; Suresh, D.; Mohanty, C.; Wang, A.; Lee, D.; Nickel, K.; Varambally, S.; Kimple, R. J.; Lambert, P. F.; Kendziorski, C.; Iyer, G.
10.1101/2023.10.02.560587 — cancer biology — Posted on 2023-10-04
4137 Finding and Following: A deep learning-based pipeline for tracking platelets during thrombus formation in vivo and ex vivo
McGovern, A. S.; Larsson, P.; Tarlac, V.; Setiabakti, N.; Shabani Mashcool, L.; Hamilton, J. R.; Boknäs, N.; Nunez-Iglesias, J.
10.1101/2023.10.02.560609 — bioinformatics — Posted on 2023-10-04
4138 Virological characteristics correlating with SARS-CoV-2 spike protein fusogenicity
Begum, M. M.; Ichihara, K.; Takahashi, O.; Nasser, H.; Jonathan, M.; Tokunaga, K.; Yoshida, I.; Nagashima, M.; Sadamasu, K.; Yoshimura, K.; Sato, K.; Ikeda, T.
10.1101/2023.10.03.560628 — microbiology — Posted on 2023-10-04
4139 Distinct functions of EHMT1 and EHMT2 in cancer chemotherapy and immunotherapy
Kang, Z.; Fu, P.; Ma, H.; Li, T.; Lu, K.; Liu, J.; Ginjala, V.; Romanienko, P.; Feng, Z.; Guan, M.; Ganesan, S.; Xia, B.
10.1101/2023.10.03.560719 — cancer biology — Posted on 2023-10-04
4140 Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
Pham, T. H.; Pahuja, K. B.; Hagenbeek, T. J.; Zbieg, J.; Noland, C. L.; Pham, V. C.; Yao, X.; Rose, C. M.; Browder, K. C.; Lee, H.-J.; Yu, M.; Liang-Chu, M.; Martin, S. E.; Verschueren, E.; Li, J.; Kubala, M. H.; Fong, R.; Lorenzo, M.; Beroza, P.; Hsu, P.; Paul, S.; Villemure, E.; Lee, W.; Cheung, T.; Clausen, S.; Lacap, J.; Liang, Y.; Cheng, J.; Schmidt, S.; Modrusan, Z.; Cohen, M. S.; Crawford, J.; Jasper, H.; Ashworth, A.; Lill, J. R.; Malek, S.; Rudolph, J.; Wertz, I. E.; Chang, M.; Ye, X.; Dey, A.
10.1101/2023.10.03.560675 — cancer biology — Posted on 2023-10-04
4141 Determinants of Disordered Protein Co-Assembly Into Discrete Condensed Phases
Welles, R. M.; Sojitra, K. A.; Garabedian, M. V.; Xia, B.; Wang, W.; Guan, M.; Regy, R. M.; Gallagher, E. R.; Hammer, D. A.; Mittal, J.; Good, M. C.
10.1101/2023.03.10.532134 — biophysics — Posted on 2023-10-04
4146 ClonoScreen3D: a novel three-dimensional clonogenic screening platform for identification of radiosensitizers for glioblastoma
Jackson, M. R.; Richards, A. R.; Oladipupo, A.-B. A.; Chahal, S. K.; Caragher, S.; Chalmers, A. J.; Gomez-Roman, N.
10.1101/2023.10.04.560635 — cancer biology — Posted on 2023-10-04
4148 Therapeutic Targeting of TIM-4-L With Engineered T Cells for Acute Myeloid Leukemia
Cieniewicz, B.; Oliveira, E.; Saxton, M.; Torabi, D.; Bhatta, A.; Kukutla, P.; Arballo, A.; Yang, Z.; Yu, B.; Fate, M.; Ning, H.; Corey, L.; Maiti, A.; Corey, D.
10.1101/2023.10.03.560752 — cancer biology — Posted on 2023-10-04
4149 Chromatinization Modulates Topoisomerase II Processivity
Lee, J.; Wu, M.; Inman, J.; Singh, G.; Park, S. h.; Lee, J. H.; Fulbright, R. M.; Hong, Y.; Jeong, J. D.; Berger, J. M.; Wang, M. D.
10.1101/2023.10.03.560726 — biophysics — Posted on 2023-10-04
4154 A DRP-like pseudoenzyme coordinates with MICOS to promote cristae architecture
Kumar, A.; Gok, M. O.; Nguyen, K. N.; Reese, M. L.; Wideman, J. G.; Munoz-Gomez, S. A.; Friedman, J. R.
10.1101/2023.10.03.560745 — cell biology — Posted on 2023-10-04
4155 A Normative Framework Dissociates Need and Motivation in Hypothalamic Neurons
Kim, K. S.; Lee, Y. H.; Kim, Y.-B.; Yun, J. W.; Song, H. Y.; Park, J. S.; Jung, S.-H.; Sohn, J.-W.; Kim, K. W.; Kim, H. R.; Choi, H. J.
10.1101/2023.10.01.560411 — neuroscience — Posted on 2023-10-04
4157 mitoBKCa is functionally expressed in murine and human breast cancer cells and promotes metabolic reprogramming
Bischof, H.; Maier, S.; Koprowski, P.; Kulawiak, B.; Burgstaller, S.; Jasinska, J.; Serafimov, K.; Gross, D.; Schroth, W.; Matt, L.; Juarez Lopez, D. A.; Bonzheim, I.; Büttner, F. A.; Fend, F.; Schwab, M.; Birkenfeld, A. L.; Malli, R.; Lämmerhofer, M.; Bednarczyk, P.; Szewczyk, A.; Lukowski, R.
10.1101/2023.10.02.560571 — cancer biology — Posted on 2023-10-04
4158 Nucleolin-RNA interaction modulates rotavirus replication
Hernandez-Guzman, J.; Arias, C.; Lopez, S.; Sandoval-Jaime, C.
10.1101/2023.10.02.560526 — microbiology — Posted on 2023-10-04
4160 The origin of intestinal cancer in the context of inflammation
Verhagen, M. P.; Joosten, R.; Schmitt, M.; Valimaki, N.; Sacchetti, A.; Rajamaki, K.; Choi, J.; Procopio, P.; Silva, S.; van der Steen, B.; van den Bosch, T. P. P.; Seinstra, D.; Doukas, M.; Augenlicht, L. H.; Aaltonen, L. A.; Fodde, R.
10.1101/2023.10.02.560432 — cancer biology — Posted on 2023-10-04
4162 The amino acid sequence determines protein abundance through its conformational stability and reduced synthesis cost.
Buric, F.; Viknander, S.; Fu, X.; Lemke, O.; Zrimec, J.; Szyrwiel, L.; Muelleder, M.; Ralser, M.; Zelezniak, A.
10.1101/2023.10.02.560091 — evolutionary biology — Posted on 2023-10-04
4163 Liver microRNA transcriptome reveals miR-182 as link between type 2 diabetes and fatty liver disease in obesity
Krause, C.; Britsemmer, J. H.; Bernecker, M.; Molenaar, A.; Taege, N.; Geissler, C.; Kaehler, M.; Iben, K.; Judycka, A.; Wagner, J.; Wolter, S.; Mann, O.; Pfluger, P.; Cascorbi, I.; Lehnert, H.; Stemmer, K.; Schriever, S. C.; Kirchner, H.
10.1101/2023.10.02.560594 — molecular biology — Posted on 2023-10-04
4165 Influenza A virus NS1 effector domain is required for PA-X mediated host shutoff
Bougon, J.; Kadijk, E.; Gallot-Lavallee, L.; Curtis, B.; Landers, M.; Archibald, J.; Khaperskyy, D.
10.1101/2023.10.02.560421 — microbiology — Posted on 2023-10-04
4166 Adolescent environmental enrichment induces social resilience and alters neural gene expression in a selectively bred rodent model with anxious phenotype
O'Connor, A. M.; Hagenauer, M. H.; Thew Forrester, L. C.; Maras, P. M.; Arakawa, K.; Hebda-Bauer, E. K.; Khalil, H.; Richardson, E.; Rob, F.; Sannah, Y.; Watson, S.; Akil, H.
10.1101/2023.10.03.560702 — neuroscience — Posted on 2023-10-04
4169 A Normative Framework Dissociates Need and Motivation in Hypothalamic Neurons
Kim, K. S.; Lee, Y. H.; Kim, Y.-B.; Yun, J. W.; Song, H. Y.; Park, J. S.; Jung, S.-H.; Sohn, J.-W.; Kim, K. W.; Kim, H. R.; Choi, H. J.
10.1101/2023.10.01.560411 — neuroscience — Posted on 2023-10-04
4170 VHL Mutation Drives Human Clear Cell Renal Cell Carcinoma Progression Through PI3K/AKT-Dependent Cholesteryl Ester Accumulation
Zhang, S.; He, Y.; Feng, W.; Zheng, Y.; Hu, S.; Fang, T.; Liu, Z.; Liu, J.; Yu, J.; He, A.; Gong, Y.; He, Z.; Yang, K.; Xi, Z.; Yu, W.; Zhou, L.; Yao, L.; Yue, S.
10.1101/2023.01.02.522447 — cancer biology — Posted on 2023-10-04
4171 Evolution of the spider homeobox gene repertoire by tandem and whole genome duplication
Aase-Remedios, M. E.; Janssen, R.; Leite, D. J.; Sumner-Rooney, L.; McGregor, A. P.
10.1101/2023.05.26.542232 — evolutionary biology — Posted on 2023-10-04
4173 SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns
Fukumura, K.; Sperotto, L.; Seuss, S.; Kang, H.-S.; Yoshimoto, R.; Sattler, M.; Mayeda, A.
10.1101/2022.12.30.522300 — molecular biology — Posted on 2023-10-04
4174 Olfactory learning modulates a neural circuit mediating innate odor-guided behavior in Drosophila
Campetella, F.; Huber, R.; Klappenbach, M.; Warnecke, C.; Locatelli, F.; Felsenberg, J.; Hansson, B. S.; Knaden, M.; Sachse, S.
10.1101/2023.09.20.558596 — neuroscience — Posted on 2023-10-04
4177 Cadherins orchestrate specific patterns of perisomatic inhibition onto distinct pyramidal cell populations
Jezequel, J.; Condomitti, G.; Kroon, T.; Hamid, F.; Sanalidou, S.; Garces, T.; Maeso, P.; Balia, M.; Rico, B.
10.1101/2023.09.28.559922 — neuroscience — Posted on 2023-10-04
4178 Novel YAP1/TAZ pathway inhibitors identified through phenotypic screening with potent anti-tumor activity via blockade of GGTase-I / Rho-GTPase signaling
Graham, K.; Lienau, P.; Bader, B.; Prechtl, S.; Naujoks, J.; Lesche, R.; Weiske, J.; Kuehnlenz, J.; Brzezinka, K.; Potze, L.; Zanconato, F.; Nicke, B.; Montebaur, A.; Bone, W.; Golfier, S.; Kaulfuss, S.; Kopitz, C.; Pilari, S.; Steuber, H.; Hayat, S.; Kamburov, A.; Steffen, A.; Schlicker, A.; Buchgraber, P.; Braeuer, N.; Font, N. A.; Heinrich, T.; Kuhnke, L.; Nowak-Reppel, K.; Stresemann, C.; Steigemann, P.; Walter, A. O.; Blotta, S.; Ocker, M.; Lakner, A.; Mumberg, D.; Eis, K.; Piccolo, S.; Lange, M.
10.1101/2023.08.30.555331 — cancer biology — Posted on 2023-10-04
4180 Tumor sialylation is a barrier against CD8 T cell-mediated anti-tumor responses and anti-PD-1 resistance in breast cancer
Mereiter, S.; Jonsson, G.; Oliveira, T.; Helm, J.; Hoffmann, D.; Abeln, M.; Jochum, A.-K.; Jochum, W.; Kellner, M. J.; Feith, M.; Tkalec, V.; Wasilewska, K.; Jiao, J.; Emsenhuber, L.; Holstein, F.; Obenauf, A.; Lordello, L.; Scoazec, J.-Y.; Kroemer, G.; Zitvogel, L.; Ali, O. H.; Flatz, L.; Gerardy-Schahn, R.; Muenster-Kuehnel, A.; Stadlmann, J.; Penninger, J. M.
10.1101/2023.09.20.558571 — cancer biology — Posted on 2023-10-04
4182 The germline coordinates mitokine signaling
Shen, K.; Durieux, J.; Mena, C. G.; Webster, B. M.; Tsui, C. K.; Zhang, H.; Joe, L.; Berendzen, K.; Dillin, A.
10.1101/2023.08.21.554217 — genetics — Posted on 2023-10-04
4185 Viral-mediated expression of Erk2 in the nucleus accumbens regulates responses to rewarding and aversive stimuli.
Parise, L. F.; Iniguez, S. D.; Warren, B. L.; Parise, E. M.; Bachtell, R.; Dietz, D.; Nestler, E. J.; Bolanos-Guzman, C.
10.1101/2023.10.03.560689 — neuroscience — Posted on 2023-10-03
4186 Distinctive and complementary roles of default mode network subsystems in semantic cognition
Shao, X.; Krieger-Redwood, K.; Zhang, M.; Hoffman, P.; Lanzoni, L.; Leech, R.; Smallwood, J.; Jefferies, E.
10.1101/2023.10.03.560166 — neuroscience — Posted on 2023-10-03
4187 Human Striatal Association Megaclusters
Kosakowski, H. L.; Saadon-Grosman, N.; Du, J.; Eldaief, M.; Buckner, R. L.
10.1101/2023.10.03.560666 — neuroscience — Posted on 2023-10-03
4189 A dual-pathway architecture enables chronic stress to promote habit formation
Giovanniello, J. R.; Paredes, N.; Wiener, A.; Ramirez-Armenta, K.; Oragwam, C.; Uwadia, H. O.; Lim, K.; Nnamdi, G.; Wang, A.; Sehgal, M.; Reis, F. M.; Sias, A. C.; Silva, A. J.; Adhikari, A.; Malvaez, M.; Wassum, K. M.
10.1101/2023.10.03.560731 — neuroscience — Posted on 2023-10-03
4190 Astrocyte aquaporin mediates a tonic water efflux maintaining brain homeostasis
Pham, C.; Komaki, Y.; Deas-Just, A.; Le Gac, B.; Mouffle, C.; Franco, C.; Vialou, V.; Tsurugizawa, T.; Cauli, B.; Li, D.
10.1101/2023.10.03.560471 — physiology — Posted on 2023-10-03
4192 Draft genomes of a male and female Australian jacky dragon (Amphibolurus muricatus)
Tian, R.; Dong, H.; Zhang, F.; Yu, H.; Pei, E.; Shi, C.; Fan, G.; Whiteley, S. L.; Holleley, C. E.; Seim, I.; Georges, A.
10.1101/2021.10.11.463868 — genomics — Posted on 2023-10-03
4193 The ortholog of human REEP1-4 is required for autophagosomal enclosure of ER-phagy/nucleophagy cargos in fission yeast
Zou, C.-X.; Ma, Z.-H.; Jiang, Z.; Pan, Z.-Q.; Xu, D.-D.; Suo, F.; Shao, G.-C.; Dong, M.-Q.; Du, L.-L.
10.1101/2023.04.24.538066 — cell biology — Posted on 2023-10-03
4194 Backbone extension acyl rearrangements enable cellular synthesis of proteins with internal β2-peptide linkages
Schepartz, A.; Roe, L.; Schissel, C. K.; Dover, T. L.; Shah, B.; Hamlish, N. X.; Zheng, S.; Dilworth, D. A.; Wong, N.; Zhang, Z.; Chatterjee, A.; Francis, M. B.; Miller, S. J.
10.1101/2023.10.03.560714 — synthetic biology — Posted on 2023-10-03
4195 Sexually dimorphic mechanisms of VGLUT-mediated protection from dopaminergic neurodegeneration
Buck, S. A.; Rubin, S. A.; Kunkhyen, T.; Treiber, C. D.; Xue, X.; Fenno, L. E.; Mabry, S. J.; Sundar, V. R.; Yang, Z.; Shah, D.; Ketchesin, K. D.; Becker-Krail, D. D.; Vasylieva, I.; Smith, M. C.; Weisel, F. J.; Wang, W.; Erickson-Oberg, M. Q.; O'Leary, E. I.; Aravind, E.; Ramakrishnan, C.; Kim, Y. S.; Wu, Y.; Quick, M.; Coleman, J. A.; MacDonald, W. A.; Elbakri, R.; De Miranda, B. R.; Palladino, M. J.; McCabe, B. D.; Fish, K. N.; Seney, M. L.; Rayport, S.; Mingote, S.; Deisseroth, K.; Hnasko, T. S.; Awatramani, R.; Watson, A. M.; Waddell, S.; Cheetham, C. E.; Logan, R. W.; Freyberg, Z.
10.1101/2023.10.02.560584 — neuroscience — Posted on 2023-10-03
4204 Parkinsons VPS35 mutation induces LRRK2 mediated lysosomal association of RILPL1 and TMEM55B
Pal, P.; Taylor, M.; Lam, P. Y.; Tonelli, F.; Hecht, C. A.; Lis, P.; Nirujogi, R. S.; Phung, T. K.; Dickie, E. A.; Wightman, M.; Macartney, T.; Pfeffer, S. R.; Alessi, D. R.
10.1101/2023.06.07.544051 — neuroscience — Posted on 2023-10-03
4205 Programming dynamic division of labor using horizontal gene transfer
Hamrick, G. S.; Maddamsetti, R.; Son, H.-I.; Wilson, M. L.; Davis, H. M.; You, L.
10.1101/2023.10.03.560696 — synthetic biology — Posted on 2023-10-03
4206 Predicting the effect of CRISPR-Cas9-based epigenome editing
Batra, S. S.; Cabrera, A.; Spence, J. P.; Hilton, I.; Song, Y. S.
10.1101/2023.10.03.560674 — bioinformatics — Posted on 2023-10-03
4209 NMR structure of the Orf63 pro-lytic protein from lambda bacteriophage
Khan, N.; Graham, T.; Franciszkiewicz, K.; Bloch, S.; Nejman-Falenczyk, B.; Wegrzyn, A.; Donaldson, L. W.
10.1101/2023.10.03.560691 — biochemistry — Posted on 2023-10-03
4210 Improving protein expression, stability, and function with ProteinMPNN
Sumida, K. H.; Nunez Franco, R.; Kalvet, I.; Pellock, S. J.; Wicky, B. I. M.; Milles, L. F.; Dauparas, J.; Wang, J.; Kipnis, Y.; Jameson, N.; Kang, A.; De La Cruz, J.; Sankaran, B.; Bera, A. K.; Jimenez Oses, G.; Baker, D.
10.1101/2023.10.03.560713 — biochemistry — Posted on 2023-10-03
4214 Interfacial water confers transcription factors with dinucleotide specificity
Taipale, J.; Morgunova, E.; Yin, Y.; Zhu, F.; Xiao, T.; Sokolov, I.; Popov, A.; Laughton, C.
10.1101/2023.10.03.560647 — biochemistry — Posted on 2023-10-03
4215 CRISPR Screening in Tandem with Targeted mtDNA Damage Reveals WRNIP1 Essentiality
Sack, T.; Dhavarasa, P.; Szames, D.; O'Brien, S.; Angers, S.; Kelley, S. O.
10.1101/2023.10.03.560559 — biochemistry — Posted on 2023-10-03
4216 MFSD7c functions as a transporter of choline at the blood-brain barrier
Nguyen, X. T. A.; Le, U. T. N.; Ha, H. T. T.; Nguyen, T. Q.; Artati, A.; Leong, N. C. P.; Nguyen, D. T.; Lim, P. Y.; Susanto, A. V.; Huang, Q.; Fam, L.; Leong, N. L.; Bonne, I.; Lee, A.; Gooch, C.; Granadillo De Luque, J. L.; Yu, D.; Hua, H.; Soong, T. W.; Chang, M. W.; Wenk, M. R.; Jerzy, A.; Cazenave-Gassiot, A.; Nguyen, L. N.
10.1101/2023.10.03.560597 — biochemistry — Posted on 2023-10-03
4219 Inhibition of miR-199b-5p reduces pathological alterations in Osteoarthritis by targeting Fzd6 and Gcnt2
Feng, T.; Zhang, Q.; Li, S.-H.; Zhou, S.-h.; Wang, X.; Wang, J.-M.; Liang, F.; Yu, S.-G.; Wu, Q.
10.1101/2023.10.03.560693 — molecular biology — Posted on 2023-10-03
4220 Post-ischemic inactivation of HIF prolyl hydroxylases in endothelium promotes maladaptive kidney repair by inducing glycolysis
Tiwari, R.; Sharma, R.; Rajendran, G.; Borkowski, G. S.; An, S. Y.; Schonfeld, M. P.; O'Sullivan, J.; Schipma, M.; Zhou, Y.; Courbon, G.; David, V.; Quaggin, S. E.; Thorp, E. B.; Chandel, N. S.; Kapitsinou, P. P.
10.1101/2023.10.03.560700 — molecular biology — Posted on 2023-10-03
4222 Localized synthesis of molecular chaperones sustains neuronal proteostasis
Alecki, C.; Rizwan, J.; Le, P.; Jacob-Tomas, S.; Xu, J. S. M.; Minotti, S.; Wu, T.; Durham, H.; Yeo, G. W.; Vera, M.
10.1101/2023.10.03.560761 — molecular biology — Posted on 2023-10-03
4223 Virological characteristics correlating with SARS-CoV-2 spike protein fusogenicity
Ikeda, T.; Begum, M. M.; Ichihara, K.; Takahashi, O.; Nasser, H.; Jonathan, M.; Tokunaga, K.; Yoshida, I.; Nagashima, M.; Sadamasu, K.; Yoshimura, K.; Sato, K.
10.1101/2023.10.03.560628 — microbiology — Posted on 2023-10-03
4224 Bacteria face trade-offs in the decomposition of complex biopolymers
Guseva, K.; Mohrlok, M.; Alteio, L.; Schmidt, H.; Pollak, S.; Kaiser, C.
10.1101/2023.10.03.560709 — microbiology — Posted on 2023-10-03
4227 Identification of Determinants that Allow Maintenance of High-Level Fluoroquinolone Resistance in Acinetobacter baumannii
Hamami, E.; Huo, W.; Castaneda, A.; Bai, J.; Syal, S.; Ortiz-Martinez, J. C.; van Opijnen, T.; Geisinger, E.; Isberg, R. R.
10.1101/2023.10.03.560562 — microbiology — Posted on 2023-10-03
4228 Investigation of H9N2 avian influenza immune escape mutant that lacks haemagglutination activity
Karunarathna, T. K.; Sadeyen, J.-R.; Bhat, S.; Chang, P.; Yang, J.; Qureshi, M.; Sealy, J. E.; Daines, R.; Iqbal, M.
10.1101/2023.10.03.558847 — microbiology — Posted on 2023-10-03
4230 Cell-to-cell heterogeneity drives host-virus coexistence in a bloom-forming alga
Joffe, N.; Kuhlisch, C.; Schleyer, G.; Ahlers, N. S.; Shemi, A.; Vardi, A.
10.1101/2023.10.03.560477 — microbiology — Posted on 2023-10-03
4233 Controlling pericellular oxygen tension in cell culture reveals distinct breast cancer responses to low oxygen tensions
Rogers, Z. J.; Colombani, T. C.; Khan, S.; Bhatt, K.; Nukovic, A.; Zhou, G.; Woolston, B. M.; Taylor, C. T.; Gilkes, D. M.; Slavov, N.; Bencherif, S. A.
10.1101/2023.10.02.560369 — bioengineering — Posted on 2023-10-03
4234 A Drug-Free Pathogen Capture and Neutralizing Nasal Spray to Prevent Emerging Respiratory Infections
Joseph, J.; Baby, H. M.; Quintero, J. R.; Kenney, D.; Mebratu, Y.; Bhatia, E.; Shah, P.; Swain, K.; Kaur, S.; Li, X. L.; Mwangi, J.; Snapper, O.; Nair, R.; Agus, E.; Ranganathan, S.; Kage, J.; Gao, J.; Luo, J. N.; Yu, A.; Douam, F.; Tesfaigzi, Y.; Karp, J.; Joshi, N.
10.1101/2023.10.02.560602 — bioengineering — Posted on 2023-10-03
4235 Reconstructing the Phylogeny of Calliandra sect. Androcallis (Fabaceae): Insights from the Inclusion of Colombian Species, with a Focus on the Enigmatic Taxon Calliandra medellinensis
Arias, T.; Arenas-Castro, H.; Saldarriaga, J. D.; Idarraga-Piedrahita, A.; Lopez-Alvarez, N.; Tovar-Luque, E.; Torres-Morales, G.; Gonzalez, M. A.; Soto_Calderon, I. D.
10.1101/2023.10.02.560511 — evolutionary biology — Posted on 2023-10-03
4241 Predicting efficacy of immunotherapy in mice with triple negative breast cancer using a cholesterol PET radiotracer
Ciavattone, N. G.; Guan, J.; Farfel, A.; Desmond, T.; Viglianti, B. L.; Scott, P. J.; Brooks, A. F.; Luker, G. D.
10.1101/2023.10.02.560577 — immunology — Posted on 2023-10-03
4242 APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple continents, age groups, and body sites
Heinken, A.; Hulshof, T.; Nap, B.; Martinelli, F.; Basile, A.; O'Brolchain, A.; O'Sullivan, N. F.; Gallagher, C.; Magee, E.; McDonagh, F.; Lalor, I.; Bergin, M.; Evans, P.; Daly, R.; Farrell, R.; Delaney, R. M.; Hill, S.; McAuliffe, S. R.; Kilgannon, T.; Fleming, R. M.; Thinnes, C. C.; Thiele, I.
10.1101/2023.10.02.560573 — systems biology — Posted on 2023-10-03
4243 Keywords to success: a practical guide to maximise the visibility and impact of academic papers
Pottier, P.; Lagisz, M.; Burke, S.; Drobniak, S. M.; Downing, P. A.; Macartney, E. L.; Martinig, A. R.; Mizuno, A.; Morrison, K.; Pollo, P.; Ricolfi, L.; Tam, J.; Williams, C.; Yang, Y.; Nakagawa, S.
10.1101/2023.10.02.559861 — scientific communication and education — Posted on 2023-10-03
4244 Gene Therapy for Cardiomyopathy associated with Duchenne Muscular Dystrophy in a Pig Model
Baehr, A.; Hoppmann, P.; Bozoglu, T.; Stirm, M.; Luksch, I.; Ziegler, T.; Hornaschewitz, N.; Shresta, S.; Shashikadze, B.; Stöckl, J. B.; Raad, N.; Blum, H.; Krebs, S.; Fröhlich, T.; Baumgartner, C.; Nowak-Imialek, M.; Walter, M.; Weber, C.; Engelhardt, S.; Moretti, A.; Klymiuk, N.; Wurst, W.; Laugwitz, K. L.; Hajjar, R. J.; Wolf, E.; Kupatt, C.
10.1101/2023.10.02.560452 — physiology — Posted on 2023-10-03
4245 Selenocysteine tRNA methylation promotes oxidative stress resistance in melanoma metastasis
Nease, L. A.; Church, K. P.; Delclaux, I.; Murakami, S.; Amiama, M. A.; Zerhouni, M.; Cascio, G.; Hughes, R. O.; Zumbo, P.; Dow, L. E.; Jaffrey, S. R.; Betel, D.; Piskounova, E.
10.1101/2023.10.02.560568 — cancer biology — Posted on 2023-10-03
4246 NanoNERF: A nanoscale NERF blaster replica made of DNA
Takiguchi, L. P.; Rober, M. B.; Olvera, J. G.; Shipley, W.; Wacker, A. L.; Fantasia, R. J.; Liu, B.; Kosuri, P.
10.1101/2023.10.02.560388 — biophysics — Posted on 2023-10-03
4250 Differential Chromatin Architecture and Risk Variants in Deep Layer Excitatory Neurons and Grey Matter Microglia Contribute to Major Depressive Disorder
Chawla, A.; Cakmakci, D.; Zhang, W.; Maitra, M.; Rahimian, R.; Mitsuhashi, H.; Davoli, M. A.; Yang, J.; Chen, G. G.; Denniston, R.; Mash, D.; Mechawar, N.; Suderman, M.; Li, Y.; Nagy, C.; Turecki, G.
10.1101/2023.10.02.560567 — genomics — Posted on 2023-10-03
4251 Molecular mechanisms of seasonal brain shrinkage and regrowth inSorex araneus
Thomas, W. R.; Dechmann, D. K. N.; Nieland, J.; Elverfeldt, D.; Carlson, D.; Baldoni, C.; Holm-Jacobsen, J.; Muturi, M.; Corthals, A.; Davalos, L.
10.1101/2023.10.02.560485 — genetics — Posted on 2023-10-03
4253 Break-induced replication underlies formation of inverted triplications and generates unexpected diversity in haplotype structures
Grochowski, C. M.; Bengtsson, J. D.; Du, H.; Gandhi, M.; Lun, M. Y.; Mehaffey, M. G.; Park, K.; Hoeps, W.; Benito-Garagorri, E.; Hasenfeld, P.; Korbel, J. O.; Mahmoud, M.; Paulin, L. F.; Jhangiani, S. N.; Muzny, D. M.; Faith, J. M.; Gibbs, R. A.; Pendleton, M.; Harrington, E.; Juul, S.; Lindstrand, A.; Sedlazeck, F. J.; Pehlivan, D.; Lupski, J. R.; Carvalho, C. M. B.
10.1101/2023.10.02.560172 — genetics — Posted on 2023-10-03
4258 Multimodal profiling of peripheral blood identifies proliferating circulating effector CD4+ T cells as predictors for response to integrin α4β7-blocking therapy in patients with inflammatory bowel disease
Horn, V.; Cancino, C.; Steinheuer, L.; Obermayer, B.; Fritz, K.; Nguyen, A. L.; Plattner, C.; Boesel, D.; Burns, M.; Schulz, A. R.; Mantzivi, E.; Lissner, D.; Conrad, T.; Mashreghi, M.-F.; Sonnenberg, E.; Beule, D.; Flatz, L.; TRR241 IBDome Consortium, ; Trajanoski, Z.; Weidinger, C.; Mei, H.; Siegmund, B.; Thurley, K.; Hegazy, A. N.
10.1101/2023.10.01.560386 — immunology — Posted on 2023-10-03
4260 Rolling 2D Bioelectronic film into 1D: a Suturable Long-term Implantable Soft Microfiber
Xie, R.; Yu, Q.; Li, D.; Han, X.; Xu, X.; Huang, J.; Zhou, X.; Tian, Q.; Li, Q.; Li, H.; Li, G.; Han, F.; Xu, T.; Liu, Z.
10.1101/2023.10.02.560392 — neuroscience — Posted on 2023-10-03
4262 Selective Mitochondrial Respiratory Complex I Subunit Deficiency Causes Tumor Immunogenicity
Liang, J.; Vitale, T.; Zhang, X.; Jackson, T. D.; Yu, D.; Jedrychowsk, M.; Gygi, S. P.; Widlund, H. R.; Wucherpfennig, K.; Puigserver, P.
10.1101/2023.10.02.560316 — cancer biology — Posted on 2023-10-03
4263 Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
Pathak, T.; Benson, J. C.; Johnson, M. T.; Xin, P.; Abdelnaby, A. E.; Walter, V.; Kultun, W. A.; Yochum, G. S.; Hempel, N.; Trebak, M.
10.1101/2023.10.02.560521 — cancer biology — Posted on 2023-10-03
4264 Assessment of three-dimensional RNA structure prediction in CASP15
Das, R.; Kretsch, R. C.; Simpkin, A. J.; Mulvaney, T.; Pham, P.; Rangan, R.; Bu, F.; Keegan, R. M.; Topf, M.; Rigden, D. J.; Miao, Z.; Westhof, E.
10.1101/2023.04.25.538330 — biophysics — Posted on 2023-10-03
4265 Digenic variant interpretation with hypothesis-driven explainable AI
De Paoli, F.; Nicora, G.; Berardelli, S.; Gazzo, A. M.; Bellazzi, R.; Magni, P.; Rizzo, E.; Limongelli, I.; Zucca, S.
10.1101/2023.10.02.560464 — bioinformatics — Posted on 2023-10-03
4266 A compact, ultrahigh-density headstage with high-fidelity hybrid integration for large-scale deep-brain opto-electrophysiology
Oh, S.; Kim, K.; Lopez Ruiz, J. R.; Slager, N.; Ko, E.; Vöröslakos, M.; Lanzio, V.; Song, H.; Park, S.-Y.; Yoon, E.
10.1101/2023.10.02.560174 — bioengineering — Posted on 2023-10-03
4267 Spiral NeuroString: High-Density Soft Bioelectronic Fibers for Multimodal Sensing and Stimulation
Khatib, M.; Zhao, E. T.; Wei, S.; Abramson, A.; Bishop, E. B.; Chen, C.-H.; Thomas, A.-L.; Xu, C.; Park, J.; Lee, Y.; Hamnett, R.; Yu, W.; Root, S. E.; Yuan, L.; Chakhtoura, D.; Kim, K. K.; Zhong, D.; Nishio, Y.; Zhao, C.; Wu, C.; Jiang, Y.; Zhang, A.; Li, J.; Wang, W.; Salimi-Jazi, F.; Rafeeqi, T. A.; Hemed, N. M.; Tok, J. B.-H.; Chen, X.; Kaltschmidt, J. A.; Dunn, J.; Bao, Z.
10.1101/2023.10.02.560482 — bioengineering — Posted on 2023-10-03
4269 The macronuclear genomic landscape within Tetrahymena thermophila
Derelle, R.; Verdonck, R.; Jacob, S.; Huet, M.; Akerman, I.; Philippe, H.; Legrand, D.
10.1101/2023.10.02.560512 — genomics — Posted on 2023-10-03
4270 Evolution of sex-biased gene expression during transitions to separate sexes in the Silene genus
Prentout, D.; Muyle, A.; Zemp, N.; El Filali, A.; Boussau, B.; Touzet, P.; Widmer, A.; Kafer, J.; Marais, G. A.
10.1101/2023.10.02.560480 — evolutionary biology — Posted on 2023-10-03
4271 Biocalcification in porcelaneous foraminifera
Dubicka, Z.; Tyszka, J.; Palczynska, A.; Hohne, M.; Bijma, J.; Janse, M.; Klerks, N.; Bickmeyer, U.
10.1101/2023.10.02.560476 — evolutionary biology — Posted on 2023-10-03
4274 A Mechanistic Insight into Sources of Error of Visual Working Memory in Multiple Sclerosis
Motahharynia, A.; Pourmohammadi, A.; Adibi, A.; Shaygannejad, V.; Ashtari, F.; Adibi, I.; Sanayei, M.
10.1101/2023.02.20.529229 — neuroscience — Posted on 2023-10-03
4276 OPTIMIZING THERAPEUTIC TARGETS FOR BREAST CANCER USING BOOLEAN NETWORK MODELS
Sgariglia, D.; Goncalves Carneiro, F. R.; Vidal de Carvalho, L. A.; Pedreira, C. E.; Carels, N.; Barbosa da Silva, F. A.
10.1101/2023.05.10.540187 — cancer biology — Posted on 2023-10-03
4277 What do we gain when tolerating loss? The information bottleneck wrings out recombination
Narechania, A.; Bobo, D.; DeSalle, R.; Mathema, B.; Kreiswirth, B. N.; Planet, P. J.
10.1101/2021.08.27.457981 — evolutionary biology — Posted on 2023-10-03
4278 Spatially and Functionally Distinct mTORC1 Entities Orchestrate the Cellular Response to Amino Acid Availability
Fernandes, S. A.; Angelidaki, D.-D.; Nuechel, J.; Pan, J.; Gollwitzer, P.; Elkis, Y.; Artoni, F.; Wilhelm, S.; Kovacevic-Sarmiento, M.; Demetriades, C.
10.1101/2023.10.03.559930 — cell biology — Posted on 2023-10-03
4280 Insulin receptor turnover in fasting is dependent on beta-dystroglycan deglycosylation
Joseph, S.; Zbidat, S.; Volodin, A.; Kasiviswanathan, D.; Fried, A. I.; Armani, A.; Gilda, J. E.; Cohen, S.
10.1101/2022.06.24.497215 — cell biology — Posted on 2023-10-03
4283 BK channel gain-of-function disrupts limb control by suppressing neurotransmission during a critical developmental window
Lowe, S. A.; Wilson, A. D.; Aughey, G.; Banarjee, A.; Goble, T.; Simon-Batsford, N.; Sanderson, A.; Kratschmer, P.; Balogun, M.; Gao, H.; Aw, S. S.; Jepson, J. E. C.
10.1101/2023.09.20.558625 — neuroscience — Posted on 2023-10-03
4284 Exploratory Correlation of The Human Structural Connectome with Non-MRI Variables in Alzheimer's Disease
Aganj, I.; Mora, J.; Frau-Pascual, A.; Fischl, B. R.; Alzheimer's Disease Neuroimaging Initiative,
10.1101/2023.06.30.547308 — neuroscience — Posted on 2023-10-03
4287 Pathformer: biological pathway informed Transformer model integrating multi-modal data
Liu, X.; Tao, Y.; Cai, Z.; Bao, P.; Ma, H.; Li, K.; Li, M.; Zhu, Y.; Lu, Z. J.
10.1101/2023.05.23.541554 — bioinformatics — Posted on 2023-10-03
4288 Marine particle microbiomes during a spring diatom bloom contain active sulfate-reducing bacteria
Siebers, R.; Schultz, D.; Farza, S. M.; Brauer, A.; Zuehlke, D.; Hoff, K.; Muecke, P. A.; Wang, F.; Bernhardt, J.; Teeling, H.; Becher, D.; Riedel, K.; Kirstein, I. V.; Wiltshire, K. H.; Schweder, T.; Urich, T.; Bengtsson, M. M.
10.1101/2022.05.31.494182 — ecology — Posted on 2023-10-03
4289 Seasonality of host-seeking Ixodes ricinus nymph abundance in relation to climate
Hoch, T.; Madouasse, A.; Jacquot, M.; Wongnak, P.; Beugnet, F.; Bournez, L.; Huard, F.; Moutailler, S.; Plantard, O.; Poux, V.; Rene-Martellet, M.; Vayssier-Taussat, M.; Verheyden, H.; Vourc'h, G.; Chalvet-Monfray, K.; Agoulon, A.
10.1101/2022.07.25.501416 — ecology — Posted on 2023-10-03
4294 Colchicine promotes atherosclerotic plaque stability independently of inflammation
Li, W.; Lin, A.; Hutton, M.; Dhaliwal, H.; Nadel, J.; Rodor, J.; Tumanov, S.; Örd, T.; Hadden, M.; Mokry, M.; Mol, B. M.; Pasterkamp, G.; Padula, M. P.; Geczy, C. L.; Ramaswamy, Y.; Sluimer, J. C.; Kaikkonen, M. U.; Stocker, R.; Baker, A.; Fisher, E.; Patel, S.; Misra, A.
10.1101/2023.10.03.560632 — cell biology — Posted on 2023-10-03
4295 An enzyme-free, cold-process acoustic method for gentle and effective tissue dissociation
MacMullan, M. A.; Busalacchi, M.; Quisling, S.; Quast, B.; Pullen, J.; Addington, S.; Vivek, V.; Levers, S.; Renkema, K.
10.1101/2023.10.03.560704 — cell biology — Posted on 2023-10-03
4296 M1-derived extracellular vesicles polarize recipient macrophages into M2 and alter skeletal muscle homeostasis in a hyper-glucose environment
Tacconi, S.; Vari, F.; Sbarigia, C.; Vardanyan, D.; Longo, S.; Mura, F.; Angile, F.; Jalabart, A.; Vergara, D.; Fanizzi, F. P.; Rossi, M.; Errazuriz-Cerda, E.; Cassin, C.; Nieuwland, R.; Giudetti, A. M.; Rome, S.; Dini, L.
10.1101/2023.10.03.560690 — cell biology — Posted on 2023-10-03
4299 Lineage frequency time series reveal elevated levels of genetic drift in SARS-CoV-2 transmission in England
Yu, Q.; Ascensao, J. A.; Okada, T.; The COVID-19 Genomics UK (COG-UK) consortium, ; Boyd, O.; Volz, E.; Hallatschek, O.
10.1101/2022.11.21.517390 — evolutionary biology — Posted on 2023-10-03
4301 Microclimate buffering varies across forest types during an extreme heat event
John, A.; Pradhan, K.; Case, M.; Ettinger, A.; Hille Ris Lambers, J.
10.1101/2023.10.02.560390 — ecology — Posted on 2023-10-03
4302 Drivers of thermal tolerance breadth of plants across contrasting biomes: do mean or seasonality in climate indices matter more?
Briceno, V. F.; Cook, A. M.; Courtney Jones, S. K.; Arnold, P. A.; Gallagher, R. V.; French, K.; Bravo, L. A.; Nicotra, A. B.; Leigh, A.
10.1101/2023.10.02.560437 — ecology — Posted on 2023-10-03
4304 Blood DDIT4 and TRIM13 transcript levels mark the early stages of Machado-Joseph disease
Ferreira, A. F.; Raposo, M.; Shaw, E. D.; Vasconcelos, J.; Kay, T.; Bettencourt, C.; Saraiva-Pereira, M. L.; Jardim, L. B.; Costa, M. d. C.; Lima, M.
10.1101/2023.10.01.560372 — neuroscience — Posted on 2023-10-03
4306 Old foe, new host: epidemiology, genetic diversity and pathogenic characterization of maize streak virus in rice fields from Burkina Faso.
Fouad, N. M. I.; Barro, M.; Bangratz, M.; Sereme, D.; Filloux, D.; Fernandez, E.; Julian, C.; Saibou, N.; Kassankogno, A. I.; Guigma, A. K.; Roumagnac, P.; Wonni, I.; Tollenaere, C.; Poulicard, N.
10.1101/2023.10.02.560455 — pathology — Posted on 2023-10-03
4307 Tumor-agnostic transcriptome-based classifier identifies spatial infiltration patterns of CD8+ T cells in the tumor microenvironment and predicts clinical outcome in early- and late-phase clinical trials
Roller, A.; Davydov, I. I.; Schwalie, P. C.; Serrano-Serrano, M. L.; Heller, A.; Staedler, N.; Ferreira, C. S.; Dietmann, G.; Klaman, I.; Valdeolivas, A.; Korski, K.; Cannarile, M. A.
10.1101/2023.10.02.560086 — cancer biology — Posted on 2023-10-03
4308 53BP1 mediates sensitivity to chemotherapy and is associated with poor clinical outcomes in high-grade serous ovarian cancer
Skulimowski, M.; Bourbonnais, J.; Malaquin, N.; Fleury, H.; Clement, I.; Communal, L.; Rahimi, K.; Provencher, D.; Mes-Masson, A.-M.; Rodier, F.
10.1101/2023.09.30.560286 — cancer biology — Posted on 2023-10-03
4310 WOMBAT-P: Benchmarking Label-Free Proteomics Data Analysis Workflows
Bouyssie, D.; Altiner, P.; Capella-Gutierrez, S.; Fernandez, J. M.; Hagemeijer, Y. P.; Horvatovich, P.; Hubalek, M.; Levander, F.; Mauri, P.; Palmblad, M.; Raffelsberger, W.; Rodriguez-Navas, L.; Di Silvestre, D.; Kunkli, B. T.; Uszkoreit, J.; Vandenbrouck, Y.; Vizcaino, J. A.; Winkelhardt, D.; Schwämmle, V.
10.1101/2023.10.02.560412 — bioinformatics — Posted on 2023-10-03
4315 De-suppression of mesenchymal cell identities and variable phenotypic outcomes associated with knockout of Bbs1.
Freke, G.; Martins, T.; Davies, R.; Beyer, T.; Seda, M.; Peskett, E.; Haq, N.; Prasai, A.; Otto, G.; Jeyabalan Srikaran, J.; Hernandez, V.; Diwan, G.; Russell, R. B.; Ueffing, M.; Huranova, M.; Boldt, K.; Beales, P. L.; Jenkins, D.
10.1101/2023.10.02.560442 — genetics — Posted on 2023-10-03
4322 Identifying targetable metabolic dependencies across colorectal cancer progression
Legge, D. N.; Stanko, E.; Holt, A. K.; Bull, C. J.; Collard, T. J.; Kollareddy, M.; Bellamy, J.; Groves, S.; Ma, E. H.; Hazelwood, E.; Qualtrough, D.; Amulic, B.; Malik, K. N.; Williams, A. C.; Jones, N.; Vincent, E. E.
10.1101/2022.03.23.485483 — cancer biology — Posted on 2023-10-03
4323 SNP discovery by exome capture and resequencing in a pea genetic resource collection
Aubert, G.; Kreplak, J.; Leveugle, M.; Duborjal, H.; Klein, A.; Boucherot, K.; Vieille, E.; Chabert-Martinello, M.; Cruaud, C.; Bourion, V.; Lejeune-Henaut, I.; Pilet-Nayel, M.-L.; Bouchenak-Khelladi, Y.; Francillonne, N.; Tayeh, N.; Pichon, J.-P.; Riviere, N.; Burstin, J.
10.1101/2022.08.03.502586 — genomics — Posted on 2023-10-03
4325 Impaired LAIR-1-mediated immune control due to collagen degradation in fibrosis
Carvalheiro, T.; Marut, W.; Pascoal Ramos, M. I.; Garcia, S.; Fleury, D.; Affandi, A. J.; Meijers, A. S.; Giovannone, B.; Tieland, R. G.; Elshof, E.; Ottria, A.; Cossu, M.; Meizlish, M. L.; Veenendaal, T.; Ramanujam, M.; Moreno-Garcia, M. E.; Klumperman, J.; Liv, N.; Radstake, T. R. D. J.; Meyaard, L.
10.1101/2021.12.07.471103 — immunology — Posted on 2023-10-03
4328 Mitochondrial CISD1 is a downstream target that mediates PINK1 and Parkin loss-of-function phenotypes
Bitar, S.; Baumann, T.; Weber, C.; Abusaada, M.; Rojas-Charry, L.; Ziegler, P.; Schettgen, T.; Randerath, I. E.; Venkataramani, V.; Michalke, B.; Arena, G.; Krueger, R.; Zhang, L.; Methner, A.
10.1101/2023.09.28.559909 — neuroscience — Posted on 2023-10-03
4329 Profound seizure suppression and disease modification by targeting JAK1, a key driver of a pro-epileptogenic gene network.
Hoffman, O. R.; Patterson, A.; Gohar, E.; Coleman, E.; Schoenike, B.; Espinosa-Garcia, C.; Paredes, F.; Dingledine, R.; Maguire, J.; Roopra, A. S.
10.1101/2023.08.07.552299 — neuroscience — Posted on 2023-10-03
4330 Development of properly-polarized trophoblast stem cell-derived organoids to model early human pregnancy
Zhou, J.; Sheridan, M. A.; Tian, Y.; Dahlgren, K. J.; Messler, M.; Peng, T.; Ezashi, T.; Schulz, L. C.; Ulery, B.; Roberts, R. M.; Schust, D. J.
10.1101/2023.09.30.560327 — developmental biology — Posted on 2023-10-03
4334 Genetic or pharmacological inactivation of CREBBP sensitizes B-cell Acute Lymphoblastic Leukemia to Ferroptotic Cell Death upon BCL2 Inhibition
Garcia-Gimenez, A.; Ditcham, J. E.; Azazi, D. M. A.; Meduri, E.; Asby, R.; Sakakini, N.; Lopez, C. K.; Narayan, N.; Beinortas, T.; Bagri, J.; Agrawal Singh, S.; Giotopoulos, G.; Murphy, M. P.; Horton, S. J.; Huntly, B.; Richardson, S. E.
10.1101/2023.10.02.556536 — cancer biology — Posted on 2023-10-03
4335 Targeting Acute Myeloid Leukemia Stem Cells Through Perturbation of Mitochondrial Calcium
Sheth, A. I.; Engel, K.; Tolison, H.; Althoff, M. J.; Amaya, M. L.; Krug, A.; Young, T.; Pei, S.; Patel, S. B.; Minhajuddin, M.; Winters, A.; Miller, R.; Shelton, I.; St-Germain, J.; Ling, T.; Jones, C.; Raught, B.; Gillen, A. E.; Ransom, M. R.; Staggs, S.; Smith, C.; Pollyea, D. A.; Stevens, B. M.; Jordan, C. T.
10.1101/2023.10.02.560330 — cancer biology — Posted on 2023-10-03
4336 Heterogeneous Nuclear Ribonucleoprotein C is an Indispensable Target in Acute Myeloid Leukemia
Vijay, V.; Meacham, A.; Katzell, L. M.; Winer, A. J.; Terrell, J.; Archibald, V. L.; Vaughn, L. T.; Drusbosky, L.; Thach, E.; Welmaker, G.; Giulianotti, M.; Brothers, S.; Beurel, E.; Bubenik, J. L.; Swanson, M.; Riva, A.; Elsayed, A. H.; Lamba, J. K.; Cogle, C. R.
10.1101/2023.10.02.559746 — cancer biology — Posted on 2023-10-03
4337 Natural killer cell regulation of breast cancer stem cells mediates metastatic dormancy.
Bushnell, G. G.; Sharma, D.; Wilmot, H. C.; Zheng, M.; Fashina, T. D.; Hutchens, C. M.; Osipov, S.; Wicha, M. S.
10.1101/2023.10.02.560493 — cancer biology — Posted on 2023-10-03
4339 A novel iPSC model reveals selective vulnerability of neurons in Multiple Sulfatase Deficiency
Pham, V.; Finoti, L. S.; Cassidy, M. M.; Maguire, J. A.; Gagne, A. L.; Waxman, E. A.; French, D. L.; King, K.; Wongkittichotee, P.; Hong, X.; Schlotawa, L.; Davidson, B. L.; Ahrens-Nicklas, R. C.
10.1101/2023.10.02.560535 — cell biology — Posted on 2023-10-03
4340 Diffusion of activated ATM explains γH2AX and MDC1 spread beyond the DNA damage site
Danovski, G.; Panova, G.; Keister, B.; Georgiev, G.; Blagoev, K. B.; Stoynov, S.
10.1101/2023.10.02.560532 — cell biology — Posted on 2023-10-03
4341 Alternative Splicing of Latrophilin-3 Controls Synapse Formation
Wang, S.; Sudhof, T. C.; Sun, W.; Quake, S. R.; Roth, B. L.; DeLeon, C.
10.1101/2023.10.02.560463 — neuroscience — Posted on 2023-10-03
4345 First-in-human demonstration of floating EMG sensors and stimulators wirelessly powered and operated by volume conduction
Becerra-Fajardo, L.; Minguillon, J.; Krob, M. O.; Rodrigues, C.; Gonzalez-Sanchez, M.; Megia-Garcia, A.; Redondo Galan, C.; Gutierrez Henares, F.; Comerma, A.; del-Ama, A. J.; Gil-Agudo, A.; Grandas, F.; Schneider-Ickert, A.; Oliveira Barroso, F.; Ivorra, A.
10.1101/2023.06.30.547056 — bioengineering — Posted on 2023-10-02
4346 Large captivity effect based on gene expression comparisons between captive and wild shrew brains
Bedoya Duque, M. A.; Thomas, W. R.; Dechmann, D. K. N.; Nieland, J. D.; Baldoni, C.; von Elverfeldt, D.; Muturi, M.; Corthals, A.; Davalos, L. M.
10.1101/2023.10.02.560583 — genetics — Posted on 2023-10-03
4348 Asymmetric cortical projections to striatal direct and indirect pathways distinctly control actions
Klug, J. R.; Yan, X.; Hoffman, H.; Engelhardt, M. D.; Osakada, F.; Callaway, E.; Jin, X.
10.1101/2023.10.02.560589 — neuroscience — Posted on 2023-10-03
4350 A Retina-inspired Optoelectronic Synapse Using Quantum Dots for Neuromorphic Photostimulation of Neurons
Balamur, R.; Eren, G. O.; Kaleli, H. N.; Karatum, O.; Kaya, L.; Hasanreisoglu, M.; Nizamoglu, S.
10.1101/2023.09.30.560306 — bioengineering — Posted on 2023-10-02
4353 On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity.
Edgar, R. C.; Siddiqui, G.; Malcolm, T. R.; Duffy, S.; Chowdhury, M.; Marfurt, J.; Wirjanata, G.; Noviyanti, R.; Daware, K.; Dans, M.; Suraweera, C. D.; Counihan, N. A.; Price, R. N.; Whittlin, S.; Avery, V. M.; Drinkwater, N.; Charman, S. A.; Creek, D. J.; Giannangelo, C.; Challis, M.; de Koning-Ward, T. F.; Scammells, P. J.; McGowan, S.
10.1101/2023.10.01.560396 — microbiology — Posted on 2023-10-02
4357 Assessment of brain-derived extracellular vesicle enrichment for blood biomarker analysis in age-related neurodegenerative diseases: An international overview
Badhwar, A.; Hirschberg, Y.; Tamayo, N. V.; Iulita, M. F.; Udeh-Momoh, C. T.; Matton, A.; Tarawneh, R. M.; Rissman, R. A.; Ledreux, A.; Winston, C. N.; Haqqani, A. S.; Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment, BBB-EWG,
10.1101/2023.10.02.560210 — neuroscience — Posted on 2023-10-02
4362 C4 Grasses Employ Various Strategies to Acclimate Rubisco Activase to Heat Stress
Stainbrook, S. C.; Aubuchon, L. N.; Chen, A.; Johnson, E.; Si, A.; Walton, L.; Ahrendt, A.; Strenkert, D.; Jez, J. M.
10.1101/2022.08.24.505184 — plant biology — Posted on 2023-10-02
4366 Single-fly assemblies fill major phylogenomic gaps across the Drosophilidae Tree of Life
Kim, B. Y.; Gellert, H. R.; Church, S. H.; Suvorov, A.; Anderson, S. S.; Barmina, O.; Beskid, S. G.; Comeault, A. A.; Crown, K. N.; Diamond, S. E.; Dorus, S.; Fujichika, T.; Hemker, J. A.; Hrcek, J.; Kankare, M.; Katoh, T.; Magnacca, K. N.; Martin, R. A.; Matsunaga, T.; Medeiros, M. J.; Miller, D. E.; Pitnick, S.; Simoni, S.; Steenwinkel, T. E.; Schiffer, M.; Syed, Z. A.; Takahashi, A.; Wei, K. H.-C.; Yokoyama, T.; Eisen, M. B.; Kopp, A.; Matute, D.; Obbard, D. J.; O'Grady, P. M.; Price, D. K.; Toda, M. J.; Werner, T.; Petrov, D. A.
10.1101/2023.10.02.560517 — evolutionary biology — Posted on 2023-10-02
4369 Non-canonical activation of IRE1α during Candida albicans infection enhances macrophage fungicidal activity
McFadden, M. J.; Reynolds, M. B.; Michmerhuizen, B. C.; Anderson, F. M.; O'Riordan, M. X. D.; O'Meara, T. R.
10.1101/2023.10.02.560560 — molecular biology — Posted on 2023-10-02
4370 Quantitative target engagement of RIPK1 in human whole blood via the cellular thermal shift assay for potential pre-clinical and clinical applications
Patel, S.; Karlsson, M.; Klahn, J. T.; Gambino, F.; Costa, H.; McGuire, K. A.; Baumgartner, C. K.; Williams, J.; Sandoz, S.; Kath, J. E.
10.1101/2023.10.02.560523 — molecular biology — Posted on 2023-10-02
4373 The Biofilm Lifestyle Shapes the Evolution of β-Lactamases
Lorentzen, O. M.; Haukefer, A. S. B.; Johnsen, P. J.; Frohlich, C.
10.1101/2023.10.02.560492 — microbiology — Posted on 2023-10-02
4375 Dry surface biofilm formation by Candida auris facilitates persistence and tolerance to sodium hypochlorite
Ware, A.; Delaney, C.; Johnston, W.; Butcher, M. C.; Ramage, G.; Price, L.; Butcher, J.; Kean, R.
10.1101/2023.10.02.560537 — microbiology — Posted on 2023-10-02
4376 Gut metabolite L-lactate supports Campylobacter jejuni population expansion during acute infection
Sinha, R.; LeVeque, R. M.; Callahan, S. M.; Stopnisek, N.; Kuipel, M.; Johnson, J. G.; DiRita, V. J.
10.1101/2023.10.02.560557 — microbiology — Posted on 2023-10-02
4379 Layer 1 NDNF Interneurons are Specialized Top-Down Master Regulators of Cortical Circuits
Hartung, J.; Schroeder, A.; Perez Vazquez, R. A.; Poorthuis, R. B.; Letzkus, J. J.
10.1101/2023.10.02.560136 — neuroscience — Posted on 2023-10-02
4384 Sea squirt-inspired bio-derived tissue sealants
Menon, A. V.; Torres, J. E.; Cox, A. D.; Risselada, M.; Schmidt, G.; Wilker, J. J.; Liu, J. C.
10.1101/2023.10.02.560578 — bioengineering — Posted on 2023-10-02
4385 Allosteric activation of VCP, a AAA unfoldase, by small molecule mimicry
Jones, N. H.; Liu, Q.; Urnavicius, L.; Dahan, N. E.; Vostal, L. E.; Kapoor, T. M.
10.1101/2023.10.02.560478 — biochemistry — Posted on 2023-10-02
4386 Identification and structural characterization of small-molecule inhibitors of PINK1
Rasool, S.; Shomali, T.; Truong, L.; Croteau, N.; Veyron, S.; Trempe, J.-F.
10.1101/2023.10.02.560389 — biochemistry — Posted on 2023-10-02
4388 Crystal structure of a Class A beta-lactamase from Nocardia cyriacigeorgica
Feuillard, J.; Couston, J.; Benito, Y.; Hodille, E.; Dumitrescu, O.; Blaise, M.
10.1101/2023.10.02.560429 — biochemistry — Posted on 2023-10-02
4392 Parallel nonfunctionalization of CK1δ/ϵ kinase ohnologs following a whole-genome duplication event
Evans-Yamamoto, D.; Dube, A. K.; Saha, G.; Plante, S.; Bradley, D.; Gagnon-Arsenault, I.; Landry, C. R.
10.1101/2023.10.02.560513 — evolutionary biology — Posted on 2023-10-02
4394 The nutrient sensor CRTC & Sarcalumenin / Thinman represent a new pathway in cardiac hypertrophy
Dondi, C.; Vogler, G.; Gupta, A.; Walls, S. M.; Kervadec, A.; Romero, M. R.; Diop, S. B.; Goode, J.; Thomas, J. B.; Colas, A. R.; Bodmer, R.; Montminy, M.; Ocorr, K.
10.1101/2023.10.02.560407 — cell biology — Posted on 2023-10-02
4395 Distinct features of ribonucleotides within genomic DNA in Aicardi-Goutieres syndrome (AGS)-ortholog mutants of Saccharomyces cerevisiae
Kundnani, D. L.; Yang, T.; Gombolay, A.; Mukherjee, K.; Newnam, G.; Meers, C.; Mehta, Z. H.; Mouawad, C.; Storici, F.
10.1101/2023.10.02.560505 — molecular biology — Posted on 2023-10-02
4396 ExoChew: An exonuclease technique to generate single-stranded DNA libraries
Patel, K.; Lodha, C.; Smith, C.; Diggins, L.; Kolluru, V.; Ross, D.; Syed, C.; Lewis, O.; Daley, R.; Mohanty, B. K.
10.1101/2023.10.02.560524 — molecular biology — Posted on 2023-10-02
4397 Deep mutational scanning reveals a tight correlation between protein degradation and toxicity of thousands of non-native aspartoacylase protein variants
Gronbaek-Thygesen, M.; Voutsinos, V.; Johansson, K. E.; Schulze, T. K.; Cagiada, M.; Pedersen, L.; Clausen, L.; Nariya, S.; Powell, R. L.; Stein, A.; Fowler, D. M.; Lindorff-Larsen, K.; Hartmann-Petersen, R.
10.1101/2023.10.02.560410 — molecular biology — Posted on 2023-10-02
4398 Vps18 contributes to phagosome membrane integrity in Mycobacterium tuberculosis-infected macrophages.
Jani, C.; Marsh, A.; Uchil, P.; Jain, N.; Baskir, Z. R.; Glover, O.; Root, D. E.; Doench, J. G.; Barczak, A. K.
10.1101/2023.10.01.560397 — microbiology — Posted on 2023-10-02
4400 Identification of ACE2 as the Entry Receptor for Two Novel European Bat Merbecoviruses
Ma, C.; Liu, C.; Xiong, Q.; Yu, X.; Chen, Y.; Si, J.; Liu, P. L.; Tong, F.; Huang, M.; Yan, H.
10.1101/2023.10.02.560486 — microbiology — Posted on 2023-10-02
4403 Reducing work-load of pathotype and gene detection in Klebsiella pneumoniae by leveraging machine learning
Sanikhani, R.; Alizadeh Kiani, K.; Soroush, M.; Moeinirad, M.; Sanikhani, S. A.; Beheshti, M.; Tavakoli, S.; Badmasti, F.; Sadati, S. H.
10.1101/2023.10.02.560438 — microbiology — Posted on 2023-10-02
4405 A novel high throughput microwell outgrowth assay for HIV infected cells
Fenton, A.; Archin, N. M.; Turner, A.-M. W.; Joseph, S. B.; Moeser, M.; Margolis, D. M.; Browne, E. P.
10.1101/2023.10.02.560422 — microbiology — Posted on 2023-10-02
4408 Region-specific gene expression changes associated to oleoylethanolamide-induced attenuation of alcohol self-administration
Gonzalez-Portilla, M.; Montagud-Romero, S.; Mellado, S.; Rodriguez de Fonseca, F.; Pascual, M.; Rodriguez-Arias, M.
10.1101/2023.10.02.560440 — neuroscience — Posted on 2023-10-02
4409 Cytochrome P450 and Epoxide Hydrolase Metabolites in Aβ and tau-induced Neurodegeneration: Insights from Caenorhabditis elegans
Sarparast, M.; Hinman, J.; Pourmand, E.; Vonarx, D.; Ramirez, L.; Ma, W.; Liachko, N. F.; Alan, J.; Lee, K. S. S.
10.1101/2023.10.02.560527 — neuroscience — Posted on 2023-10-02
4410 Lysosomal proteomics reveals mechanisms of neuronal apoE4-associated lysosomal dysfunction
Krogsaeter, E. K.; McKetney, J.; Marquez, A.; Cakir, Z.; Stevenson, E.; Jang, G. M.; Rao, A.; Zhou, A.; Huang, Y.; Krogan, N. J.; Swaney, D. L.
10.1101/2023.10.02.560519 — neuroscience — Posted on 2023-10-02
4414 Scene-selectivity in CA1/subicular complex: Multivoxel pattern analysis at 7T
Read, M.-L.; Berry, S. C.; Graham, K. S.; Voets, N. L.; Zhang, J. C.; Aggleton, J. P.; Lawrence, A. D.; Hodgetts, C. J.
10.1101/2023.10.02.560435 — neuroscience — Posted on 2023-10-02
4416 Astrocyte-specific inhibition of primary cilium functions improves cognitive impairment during neuroinflammation by suppressing A1 astrocyte differentiation.
Muhamad, N. A. B.; Furukawa, S.; Yuri, S.; Toriyama, M.; Masutani, K.; Matsumoto, C.; Itoh, S.; Shinagawa, Y.; Isotani, A.; Toriyama, M.; Itoh, H.
10.1101/2023.10.01.560403 — neuroscience — Posted on 2023-10-02
4417 Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction in C9orf72 ALS/FTD in vivo models and patient iNeurons
Au, W. H.; Miller-Fleming, L.; Sanchez-Martinez, A.; Lee, J.; Twyning, M. J.; Prag, H.; Granger, S.; Roome, K.; Ferraiuolo, L.; Mortiboys, H.; Whitworth, A. J.
10.1101/2023.10.02.560439 — neuroscience — Posted on 2023-10-02
4420 Growth Dynamics of Ductal Carcinoma in Situ Recapitulate Normal Breast Development
Ryser, M. D.; Greenwald, M. A.; Sorribes, I. C.; King, L. M.; Hall, A.; Geradts, J.; Weaver, D. L.; Mallo, D.; Holloway, S.; Monyak, D.; Gumbert, G.; Vaez-Ghaemi, S.; Wu, E.; Murgas, K. A.; Grimm, L. J.; Maley, C. C.; Marks, J.; Shibata, D.; Hwang, S.
10.1101/2023.10.01.560370 — cancer biology — Posted on 2023-10-02
4421 DNA i-motif levels are overwhelmingly depleted in living human cells: insights from in-cell NMR.
Viskova, P.; Istvankova, E.; Rynes, J.; Dzatko, S.; Loja, T.; Lenarcic Zivkovic, M.; Rigo, R.; El Khoury, R.; Serrano-Chacon, I.; Damha, M. J.; Gonzalez Ibanez, C.; Mergny, J.-L.; Foldynova-Trantirkova, S.; Trantirek, L.
10.1101/2023.10.01.558881 — biophysics — Posted on 2023-10-02
4428 Cryo-EM structure of the CBC-ALYREF complex
Clarke, B. P.; Angelos, A. E.; Mei, M.; Hill, P. S.; Xie, Y.; Ren, Y.
10.1101/2023.10.01.559959 — molecular biology — Posted on 2023-10-02
4429 Mapping of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome
Sanfilippo, P.; Kim, A. J.; Bhukel, A.; Yoo, J.; Mirshahidi, P. S.; Pandey, V.; Bevir, H.; Yuen, A.; Mirshahidi, P. S.; Guo, P.; Li, H.-S.; Wohlschlegel, J. A.; Aso, Y.; Zipursky, S. L.
10.1101/2023.10.02.560011 — neuroscience — Posted on 2023-10-02
4438 Overlap and divergence of neural circuits mediating distinct behavioral responses to sugar
Jacobs, R. V.; Wang, C. X.; Lozada-Perdomo, F. V.; Nguyen, L.; Deere, J. U.; Uttley, H. A.; Devineni, A. V.
10.1101/2023.10.01.560401 — neuroscience — Posted on 2023-10-02
4439 Time Tiling of Learned Stimulus-Based Decision Making in Dorsal CA1 in the Hippocampus
Ma, M.; Simoes de Souza, F.; Futia, G. L.; Anderson, S. R.; Riguero, J.; Tollin, D.; Gentile-Polese, A.; Platt, J. P.; Hiratani, N.; Gibson, E. A.; Restrepo, D.
10.1101/2023.10.01.560382 — neuroscience — Posted on 2023-10-02
4442 A New Role for RNA G-quadruplexes in Aging and Alzheimer's Disease
Kallweit, L.; Saternos, H.; Hamlett, E. D.; Gilmore, A.; Granholm, A.-C.; Horowitz, S.
10.1101/2023.10.02.560545 — neuroscience — Posted on 2023-10-02
4443 The COMBO window: A chronic cranial implant for multiscale circuit interrogation in mice
Edelman, B.; Siegenthaler, D.; Wanken, P.; Jenkins, B.; Schmid, B.; Ressle, A.; Gogolla, N.; Frank, T.; Mace, E.
10.1101/2023.10.02.560470 — neuroscience — Posted on 2023-10-02
4445 Identity and Nature of Neural Stem Cells in the Adult Human Subventricular Zone
Baig, S.; Nadaf, J.; Allache, R.; Le, P. U.; Lou, M.; Djedid, A.; Safisamghabadi, M.; Prat, A.; Antel, J.; Guiot, M. C.; Petrecca, K.
10.1101/2023.10.02.560459 — neuroscience — Posted on 2023-10-02
4448 Differences in white matter detected by ex vivo 9.4T MRI are associated with axonal changes in the R6/1 model of Huntington's Disease
Casella, C.; Kelly, B.; Murillo Bartolome, A.; Mills-Smith, B.; Parker, G. D.; Von Ruhland, C.; Syed, Y. A.; Dion, V.; Rosser, A. E.; Metzler-Baddeley, C.; Jones, D. K.; Lelos, M.
10.1101/2023.10.02.560424 — neuroscience — Posted on 2023-10-02
4451 Puzzle cell shape emerges from the interaction of growth with mechanical constraints
Trozzi, N.; Lane, B.; Perruchoud, A.; Wang, Y.; Hoermayer, L.; Ansel, M.; Mollier, C.; Malivert, A.; Clark, F.; Reichgelt, T.; Roeder, A. H. K.; Hamant, O.; Boudaoud, A.; Kwiatkowska, D.; Runions, A.; Smith, R. S.; Majda, M.
10.1101/2023.10.01.560343 — plant biology — Posted on 2023-10-02
4452 Cardiac atrophy, dysfunction, and metabolic impairments: a cancer-induced heart failure phenotype
Ogilvie, L. M.; Delfinis, L. J.; Coyle-Asbil, B.; Vudatha, V.; Alshamali, R.; Garlisi, B.; Pereira, M.; Matuszewska, K.; Garibotti, M. C.; Gandhi, S.; Brunt, K. R.; Trevino, J. G.; Perry, C. G.; Petrik, J.; Simpson, J. A.
10.1101/2023.09.30.560250 — physiology — Posted on 2023-10-02
4453 Atrial t-tubules adopt a specialist developmental state while alterations to Ca2+ buffering maintain systolic Ca2+ during postnatal development
Smith, C. E. R.; Clarke, J. D.; Quinn, C. J.; Sultan, Z.; Najem, H.; Denham, N. C.; Hutchings, D. C.; Madders, G. W. P.; Caldwell, J. L.; Toms, L. K.; Pinali, C.; Eisner, D. A.; Trafford, A. W.; Dibb, K. M.
10.1101/2023.10.01.560329 — physiology — Posted on 2023-10-02
4454 Arrested Agonist Paradigm For Selective Radiosensitization of Prostate Cancer
Coulter, J. B.; Haffner, M.; Zhang, Y.; Zhou, H.; Pham, M.-T. N.; Chen, J.; Chikarmane, R.; Mishra, A.; Mehl, M. S.; Kazibwe, S.; Choi, K.; Archey, A.; Valluri, S.; Lupold, S. E.; Song, D.; De Marzo, A. M.; Nelson, W. G.; DeWeese, T. L.; Yegnasubramanian, S.
10.1101/2023.10.01.560227 — cancer biology — Posted on 2023-10-02
4455 Lysosomal acid lipase-activity as a novel target to efficiently address triple-negative breast cancer high malignancy
Steigerwald, H.; Bozzetti, T.; Tams, M.; On, J.; Hoffmann, G.; Lambertz, J.; Weidele, K.; Treitschke, S.; Reinhardt, F.; Kulik, A.; Krawczyk, N.; Niederacher, D.; Neubauer, H.; Werno, C.; Rau, T.; Fehm, T.; Esser, K.
10.1101/2023.10.01.560038 — cancer biology — Posted on 2023-10-02
4457 A Specialized Epithelial Cell Type Regulating Mucosal Immunity and Driving Human Crohn's Disease
Li, J.; Simmons, A. J.; Chiron, S.; Ramirez-Solano, M. A.; Tasneem, N.; Kaur, H.; Xu, Y.; Revetta, F.; Vega, P. N.; Bao, S.; Cui, C.; Tyree, R. N.; Raber, L. W.; Conner, A. N.; Beaulieu, D. B.; Dalal, R. L.; Horst, S. N.; Pabla, B. S.; Huo, Y.; Landman, B. A.; Roland, J. T.; Scoville, E. A.; Schwartz, D. A.; Washington, M. K.; Shyr, Y.; Wilson, K. T.; Coburn, L. A.; Lau, K. S.; Liu, Q.
10.1101/2023.09.30.560293 — bioinformatics — Posted on 2023-10-02
4459 Pan-genome of pear provides insights into the differentiation of fruit quality traits between Asian and European pears
Ding, B.; hu, h.; Liu, T.; Qamar, M. T. u.; Lin, Y.; Xu, R.; Chen, Z.; He, G.; Han, Y.; Guo, H.; Qiao, J.; Zhao, J.; Feng, X.; Yang, S.; He, S.; Li, L.; Varshney, R. K.; Guo, X.
10.1101/2023.09.29.560244 — genomics — Posted on 2023-10-02
4461 ATF7IP2/MCAF2 directs H3K9 methylation and meiotic gene regulation in the male germline
Alavattam, K. G.; Esparza, J. M.; Hu, M.; Shimada, R.; Kohrs, A. R.; Abe, H.; Munakata, Y.; Otsuka, K.; Yoshimura, S.; Kitamura, Y.; Yeh, Y.-H.; Hu, Y.-C.; Kim, J.; Andreassen, P. R.; Ishiguro, K.-i.; Namekawa, S. H.
10.1101/2023.09.30.560314 — developmental biology — Posted on 2023-10-02
4464 Antiepileptic medication strengthens excitatory neurotransmission in pyramidal neurons of the adult human neocortex
Lenz, M.; Kruse, P.; Eichler, A.; Straehle, J.; Hemeling, H.; Stöhr, P.; Beck, J.; Vlachos, A.
10.1101/2023.09.30.560289 — neuroscience — Posted on 2023-10-02
4467 Multi-modal transcriptomic analysis unravels enrichment of hybrid epithelial/mesenchymal state and enhanced phenotypic heterogeneity in basal breast cancer
Sahoo, S.; Ramu, S.; Nair, M. G.; Pillai, M.; Perez San Juan, B.; Milioli, H. Z.; Mandal, S.; Naidu, C. M.; Mavatkar, A. D.; Subramaniam, H.; Neogi, A. G.; Chaffer, C. L.; Prabhu, J. S.; Somarelli, J. A.; Jolly, M. K.
10.1101/2023.09.30.558960 — systems biology — Posted on 2023-10-02
4468 Ptth regulates lifespan through innate immunity pathway in Drosophila
Kang, P.; Liu, P.; Kim, J.; Bolton, M.; Kumar, A.; Miao, T.; Shimell, M.; O'Connor, M. B.; Powell-Coffman, J.; Bai, H.
10.1101/2023.09.30.560323 — physiology — Posted on 2023-10-02
4469 Scaling use of the rust fungus Puccinia punctiformis for biological control of Canada thistle (Cirsium arvense (L.) Scop.): First report on a U.S. statewide effort
Bean, D. W.; Gladem, K.; Rosen, K.; Blake, A.; Clark, R. E.; Henderson, C.; Kaltenbach, J.; Price, J.; Smallwood, E. L.; Berner, D. K.; Young, S. L.; Schaeffer, R. N.
10.1101/2023.09.30.560232 — pathology — Posted on 2023-10-02
4470 Physical activity regulates the immune response to breast cancer by a hematopoietic stem cell-autonomous mechanism
Khair, L.; Hayes, K.; Tutto, A.; Samant, A.; Ferreira, L.; Nguyen, T. T.; Brehm, M.; Messina, L. M.
10.1101/2023.09.30.560299 — cancer biology — Posted on 2023-10-02
4471 Bile Acids Serve As Endogenous Antagonists Of The Leukemia Inhibitory Factor (LIF) Receptor in Oncogenesis
Di Giorgio, C.; Morretta, E.; Lupia, A.; Bellini, R.; Massa, C.; Urbani, G.; Bordoni, M.; Marchiano, S.; Rapacciuolo, P.; Finamore, C.; Sepe, V.; Monti, M. C.; Monarca, F.; Natalizi, N.; Graziosi, L.; Distrutti, E.; Biagioli, M.; Catalanotti, B.; Donini, A.; Zampella, A.; Fiorucci, S.
10.1101/2023.09.30.560269 — cancer biology — Posted on 2023-10-02
4472 A senescence-like state is beneficial for ovarian cancer treatment
Skulimowski, M.; Calvo Gonzalez, L.; Cheng, S.; Clement, I.; Portelance, L.; Zhan, Y.; Carmona, E.; Lafontaine, J.; Deladurantaye, M.; Rahimi, K.; Provencher, D.; Mes-Masson, A.-M.; Rodier, F.
10.1101/2023.09.30.560300 — cancer biology — Posted on 2023-10-02
4473 An In-Silico Testbed for Fast and Accurate MR Labeling of Orthopaedic Implants
Noetscher, G. M.; Serano, P. J.; Horner, M.; Prokop, A.; Hanson, J.; Fujimoto, K.; Brown, J. E.; Nazarian, A.; Ackerman, J.; Makaroff, S. N.
10.1101/2023.07.16.549234 — biophysics — Posted on 2023-10-02
4477 Accurate Identification of Motoneuron Discharges from Ultrasound Images Across the Full Muscle Cross-Section
Lubel, E.; Rohlen, R.; Grandi Sgambato, B.; Barsakcioglu, D.; Ibanez, J.; Tang, M.-x.; Farina, D.
10.1101/2023.09.29.560220 — bioengineering — Posted on 2023-10-02
4479 Biophysical analysis reveals autophosphorylation as an important negative regulator of LRRK2 dimerization
Guaitoli, G.; Zhang, X.; Saitta, F.; Miglionico, P.; Silbermann, L. M.; Ho, F. Y.; von Zweydorf, F.; Signorelli, M.; Tych, K.; Fessas, D.; Raimondi, F.; Kortholt, A.; Gloeckner, C. J.
10.1101/2023.08.11.549911 — biochemistry — Posted on 2023-10-02
4481 Improved Resolution of Highly Pathogenic Avian Influenza Virus Haemagglutinin Cleavage Site Using Oxford Nanopore R10 Sequencing Chemistry
Ratcliff, J.; Merritt, B.; Gooden, H.; Siegers, J.; Srikanth, A.; Yann, S.; Kol, S.; Sin, S.; Tok, S.; Karlsson, E. A.; Thielen, P. M.
10.1101/2023.09.30.560331 — genomics — Posted on 2023-10-02
4482 Admix-kit: An Integrated Toolkit and Pipeline for Genetic Analyses of Admixed Populations
Hou, K.; Gogarten, S.; Kim, J.; Hua, X.; Dias, J.-A.; Sun, Q.; Wang, Y.; Tan, T.; Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium Methods Working Group, ; Atkinson, E. G.; Martin, A.; Shortt, J.; Hirbo, J.; Li, Y.; Pasaniuc, B.; Zhang, H.
10.1101/2023.09.30.560263 — genetics — Posted on 2023-10-02
4483 Pathogenic Morphological Signatures of Perturbations in Mitochondrial-Related Genes Revealed by Pooled Imaging Assay
Kremitzki, C. L.; Waligorski, J. E.; Bachman, G. W.; Mohammed Ali, L. K.; Bramley, J. C.; Vakaki, M. A.; Chandrasekaren, V. D.; Patel, P.; Mathur, D. P.; Hime, P. M.; Mitra, R. D.; Milbrandt, J. D.; Buchser, W. J.
10.1101/2023.09.30.560021 — genetics — Posted on 2023-10-02
4487 Age-associated failure of efficient cardiac proteostatic adaptations to chronic cAMP-stress is associated with accelerated heart aging
Perino, M. G.; Calvo-Rubio Barrera, M.; Agnetti, G.; Ranek, M.; Riordon, D.; Morrell, C.; Chakir, K.; Qu, J.; Tarasov, K.; Parveen, A.; Kadioglu, H.; deCabo, R.; Lakatta, E.
10.1101/2023.08.13.553128 — cell biology — Posted on 2023-10-02
4489 Neutralisation of SARS-CoV-2 Omicron subvariants BA.2.86 and EG.5.1 by antibodies induced by earlier infection or vaccination
Lassauniere, R.; Polacek, C.; Baig, S.; Ellegaard, K.; Escobar-Herrera, L. A.; Fomsgaard, A.; Spiess, K.; Schwartz, O.; Planas, D.; Simon-Loriere, E.; Schneider, U. V.; Sieber, R. N.; Stegger, M.; Krause, T. G.; Ullum, H.; Jokelainen, P.; Rasmussen, M.
10.1101/2023.10.01.560365 — immunology — Posted on 2023-10-02
4490 Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity
Carmi, Y.; Farhat-Younis, L.; Na, M.; Zarfin, A.; Santana-Magal, N.; Richter, A.; Khateeb, A.; Gutwillig, A.; Rasoulouniriana, D.; Gleiberman, A.; Beck, L.; Giger, T.; Ashkenazi, A.; Barzel, A.; Rider, P.
10.1101/2023.09.30.560338 — immunology — Posted on 2023-10-02
4491 C5aR1 signaling promotes region and age dependent synaptic pruning in models of Alzheimers Disease
Gomez-Arboledas, A.; Fonseca, M. I.; Kramar, E.; Chu, S.-H.; Schartz, N. D.; Selvan, P.; Wood, M. A.; Tenner, A. J.
10.1101/2023.09.29.560234 — neuroscience — Posted on 2023-10-02
4493 Age differences in spatial memory are mitigated during naturalistic navigation
Hill, P. F.; Bermudez, S.; McAvan, A. S.; Garren, J. D.; Grilli, M. D.; Barnes, C. A.; Ekstrom, A. D.
10.1101/2023.01.23.525279 — neuroscience — Posted on 2023-10-02
4494 A consistent map in the medial entorhinal cortex supports spatial memory
Malone, T.; Tien, N.-W.; Ma, Y.; Cui, L.; Lyu, S.; Wang, G.; Nguyen, D.; Zhang, K.; Myroshnychenko, M.; Tyan, J.; Gordon, J.; Kupferschmidt, D.; Gu, Y.
10.1101/2023.09.30.560254 — neuroscience — Posted on 2023-10-02
4496 Cellular rejuvenation protects neurons from inflammation mediated cell death.
Drake, S. S.; Mohammadnia, A.; Heale, K.; Groh, A. M. R.; Hua, E. M.- L.; Zaman, A.; Hintermayer, M. A.; Zandee, S.; Gosselin, D.; Stratton, J. A.; Sinclair, D. A.; Fournier, A. E.
10.1101/2023.09.30.560301 — neuroscience — Posted on 2023-10-02
4497 Default mode network shows distinct emotional and contextual responses yet common effects of retrieval demands across tasks
Souter, N. E.; de Freitas, A.; Zhang, M.; Shao, X.; Gonzalez Alam, T. R. d. J.; Engen, H.; Smallwood, J.; Krieger-Redwood, K.; Jefferies, E.
10.1101/2023.09.30.560279 — neuroscience — Posted on 2023-10-02
4499 Projection-specific integration of convergent thalamic and retrosplenial signals in the presubicular head direction cortex
Richevaux, L.; Lim, D.; Nassar, M.; Dias Rodrigues, L.; Mauthe, C.; Cohen, I.; Sol-Foulon, N.; Fricker, D.
10.1101/2023.03.16.533014 — neuroscience — Posted on 2023-10-02
4501 Direct serotonin release in humans shapes decision computations within aversive environments
Colwell, M. J.; Tagomori, H.; Cheng, H.; Shang, F.; Wigg, C.; Browning, M. J.; Cowen, P. J.; Murphy, S. E.; Harmer, C. J.
10.1101/2023.09.30.560111 — neuroscience — Posted on 2023-10-02
4502 Glioblastoma initiation, migration, and cell types are regulated by core bHLH transcription factors ASCL1 and OLIG2
Myers, B. L.; Brayer, K. J.; Paez-Beltran, L. E.; Keith, M. S.; Suzuki, H.; Newville, J.; Anderson, R. H.; Lo, Y.; Mertz, C. M.; Kollipara, R.; Borromeo, M. D.; Bachoo, R. M.; Johnson, J. E.; Vue, T. Y.
10.1101/2023.09.30.560206 — neuroscience — Posted on 2023-10-02
4505 Sleepiness, not total sleep amount, increases seizure risk
Cuddapah, V. A.; Hsu, C. T.; Li, Y.; Shah, H. M.; Saul, C.; Killiany, S.; Shon, J.; Yue, Z.; Gionet, G.; Putt, M. E.; Sehgal, A.
10.1101/2023.09.30.560325 — neuroscience — Posted on 2023-10-02
4509 Vitamin D constrains inflammation by modulating the expression of key genes on Chr17q12-21.1
Kılıc, A.; Halu, A.; De Marzio, M.; Maiorino, E.; Duvall, M. G.; Brüggemann, T. R.; Rojas Quintero, J. J.; Chase, R.; Mirzakhani, H.; Özge Sungur, A.; Koepke, J.; Nakano, T.; Peh, H. Y.; Krishnamoorthy, N.; Abdulnour, R.-E.; Georgopoulos, K.; Litonjua, A. A.; Demay, M. B.; Renz, H.; Levy, B. D.; Weiss, S. T.
10.1101/2022.05.22.491886 — systems biology — Posted on 2023-10-02
4512 Rhythmic lipid and gene expression responses to chilling in panicoid grasses
Kenchanmane Raju, S. K.; Zhang, Y.; Mahboub, S.; Ngu, D.; Qiu, Y.; Harmon, F.; Schnable, J. C.; Roston, R. L.
10.1101/2023.09.29.560160 — plant biology — Posted on 2023-10-02
4515 ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97
Pozner, A.; Verma, S. P.; Li, L.; Wang, S.; Barrott, J. J.; Nelson, M. L.; Yu, J. S. E.; Negri, G. L.; Colborne, S.; Hughes, C. S.; Zhu, J.-F.; Lambert, S. L.; Carroll, L. S.; Smith-Fry, K.; Stewart, M. G.; Kannan, S.; Jensen, B.; Mortenson, K. L.; John, C.; Sikdar, S.; Liu, H.; Dang, N. H.; Bourdage, J.; Li, J.; Vahrenkamp, J. M.; Groundland, J. S.; Wustrack, R.; Senger, D. L.; Zemp, F. J.; Mahoney, D. J.; Gertz, J.; Zhang, X.; Lazar, A. J.; Hirst, M.; Morin, G. B.; Nielsen, T. O.; Shen, P. S.; Jones, K. B.
10.1101/2023.09.29.560242 — cancer biology — Posted on 2023-10-02
4516 ARF6-dependent endocytic trafficking of the Interferon-γ receptor drives adaptive immune resistance in cancer.
Wee, Y.; Wang, J.; Wilson, E. C.; Rich, C. P.; Rogers, A.; Tong, Z.; DeGroot, E.; Gopal, Y. N. V.; Davies, M. A.; Ekiz, H. A.; Tay, J. K. H.; Stubben, C.; Boucher, K. M.; Oviedo, J. M.; Fairfax, K.; Williams, M. A.; Holmen, S. L.; Wolff, R.; Grossmann, A. H.
10.1101/2023.09.29.560199 — cancer biology — Posted on 2023-10-02
4518 Synthesis, Insertion and Characterization of SARS-CoV-2 Membrane Protein Within Lipid Bilayers
Zhang, Y.; Anbir, S.; Mctiernan, J.; Li, S.; Worcester, M.; Mishra, P.; Colvin, M. E.; Gopinathan, A.; Mohideen, U.; Zandi, R.; Kuhlman, T. E.
10.1101/2023.09.30.560318 — biophysics — Posted on 2023-10-02
4523 Introducing Molecular Hypernetworks forDiscovery in MultidimensionalMetabolomics Data
Colby, S. M.; Shapiro, M. R.; Lin, A.; Bilbao, A.; Broeckling, C. D.; Purvine, E.; Joslyn, C. A.
10.1101/2023.09.29.560191 — bioinformatics — Posted on 2023-10-02
4525 Gut Microbiome Wellness Index 2 for Enhanced Health Status Prediction from Gut Microbiome Taxonomic Profiles
Chang, D.; Gupta, V. K.; Hur, B.; Cobo-Lopez, S.; Cunningham, K. Y.; Han, N.; Lee, I.; Kronzer, V. L.; Teigen, L.; Karnatovskaia, L.; Longbrake, E. E.; Davis, J. M.; Nelson, H.; Sung, J.
10.1101/2023.09.30.560294 — bioinformatics — Posted on 2023-10-02
4526 Contributions of hyperactive mutations in Mpro from SARS-CoV-2 to drug resistance
Flynn, J. M.; Zvornicanin, S. N.; Shaqra, A. M.; Dovala, D.; Schiffer, C. A.; Bolon, D.
10.1101/2023.09.28.560010 — biochemistry — Posted on 2023-10-02
4527 Transcriptome analysis in a humanized mouse model of familial dysautonomia reveals tissue-specific gene expression disruption in the peripheral nervous system.
Harripaul, R. S.; Morini, E. S.; Salani, M.; Logan, E.; Kirchner, E. G.; Bolduc, J.; Chekuri, A.; Currall, B.; Yadav, R.; Erdin, S.; Talkowski, M. E.; GAO, D.; Slaugenhaupt, S.
10.1101/2023.09.28.559870 — genomics — Posted on 2023-10-02
4528 A dicer-like3 protein affects paramutation at multiple loci in Zea mays
Narain, A. S.; Liao, I. T.; Talbot, J.-E. R. B.; Deans, N. C.; Hollick, J. B.
10.1101/2023.09.29.560153 — genetics — Posted on 2023-10-02
4529 Matching maternal and paternal experiences underpin molecular thermal acclimation
Bonzi, L. C.; Donelson, J. M.; Spinks, R. K.; Munday, P. L.; Ravasi, T.; Schunter, C.
10.1101/2023.09.29.560260 — evolutionary biology — Posted on 2023-10-02
4534 Resident memory T cell development is associated with AP-1 transcription factor upregulation across anatomical niches.
Smith, N. P.; Yan, Y.; Pan, Y.; Williams, J. B.; Manakongtreecheep, K.; Pant, S.; Zhao, J.; Tian, T.; Pan, T.; Stingley, C.; Wu, K.; Zhang, J.; Kley, A. L.; Sorger, P. K.; Villani, A.-C.; Kupper, T. S.
10.1101/2023.09.29.560006 — immunology — Posted on 2023-10-02
4535 Resident Synovial Macrophages in Synovial Fluid: Implications for Immunoregulation in Infectious and Inflammatory Arthritis
Cyndari, K. I.; Scorza, B. M. I.; Zacharias, Z. R.; Strand, L.; Mahachi, K.; Oviedo, J. M.; Gibbs, L.; Pessoa-Pereira, D.; Ausdal, G.; Hendricks, D.; Yahashiri, R.; Elkins, J. M.; Gulbrandsen, T.; Peterson, A. R.; Willey, M. C.; Fairfax, K. C.; Petersen, C. A. A.
10.1101/2023.09.29.560183 — immunology — Posted on 2023-10-02
4536 Cell-binding IgM in CSF is distinctive of multiple sclerosis and targets the iron transporter SCARA5
Callegari, I.; Oechtering, J.; Schneider, M.; Perriot, S.; Mathias, A.; Voortman, M.; Cagol, A.; Lanner, U.; Diebold, M.; Holdermann, S.; Kreiner, V.; Becher, B.; Granziera, C.; Junker, A.; Du Pasquier, R.; Khalil, M.; Kuhle, J.; Kappos, L.; Sanderson, N. S.; Derfuss, T.
10.1101/2023.09.29.560121 — immunology — Posted on 2023-10-02
4538 Commensal myeloid crosstalk in neonatal skin regulates long-term cutaneous type 17 inflammation
Dhariwala, M. O.; DeRogatis, A. M.; Okoro, J. N.; Weckel, A. A.; Tran, V. M.; Habrylo, I.; Ojewumi, O. T.; Tammen, A. E.; Leech, J. M.; Merana, G. R.; Carale, R. O.; Barrere-Cain, R.; Hiam-Galvez, K. J.; Spitzer, M. H.; Scharschmidt, T. C.
10.1101/2023.09.29.560039 — immunology — Posted on 2023-10-02
4540 Stem cell-specific ecdysone signaling regulates the development and function of a Drosophila sleep homeostat
Wani, A. R.; Chowdhury, B.; Luong, J.; Chaya, G. M.; Patel, K.; Isaacman-Beck, J.; Shafer, O. T.; Kayser, M. S.; Syed, M. H.
10.1101/2023.09.29.560022 — neuroscience — Posted on 2023-10-02
4544 Identification of a convergent spinal neuron population that encodes itch
Sheahan, T. D.; Warwick, C. A.; Cui, A. Y.; Baranger, D. A.; Perry, V. J.; Smith, K. M.; Manalo, A. P.; Nguyen, E. K.; Koerber, H. R.; Ross, S. E.
10.1101/2023.09.29.560205 — neuroscience — Posted on 2023-10-02
4545 Neurophysiological and computational mechanisms of non-associative and associative memories during complex human behavior
Xiao, Y.; Sanchez Lopez, P.; Wu, R.; Srinivasan, R.; Wei, P.-H.; Shan, Y.-Z.; Weisholtz, D.; Cosgrove, W. R.; Madsen, J. R.; Stone, S.; Zhao, G.-G.; Kreiman, G.
10.1101/2023.03.27.534384 — neuroscience — Posted on 2023-10-02
4546 Parametric information about eye movements is sent to the ears
Lovich, S. N.; King, C. D.; Murphy, D. L. K.; Landrum, R.; Shera, C. A.; Groh, J. M.
10.1101/2022.11.27.518089 — neuroscience — Posted on 2023-10-02
4547 Regulation of astrocyte metabolism by mitochondrial translocator protein 18kDa
Firth, W.; Robb, J. L.; Stewart, D.; Pye, K. R.; Bamford, R.; Oguro-Ando, A.; Beall, C.; Ellacott, K. L.
10.1101/2023.09.29.560159 — neuroscience — Posted on 2023-10-02
4548 Endosomal dysfunction contributes to cerebellar deficits in spinocerebellar ataxia type 6
Cook, A. A.; Leung, T. C. S.; Rice, M.; Nachman, M.; Zadigue-Dube, E.; Watt, A. J.
10.1101/2023.06.26.546542 — neuroscience — Posted on 2023-10-02
4550 Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver Identifies Tissue- and Sex-Specific Changes with Implications for Genetic Imprinting
Morgan, R. K.; Wang, K.; Svoboda, L. K.; Rygiel, C. A.; Lalancette, C.; Cavalcante, R.; Bartolomei, M. S.; Prasasya, R. D.; Neier, K.; Perera, B. P.; Jones, T. R.; Colacino, J. A.; Sartor, M. A.; Dolinoy, D. C.
10.1101/2023.09.29.560131 — pharmacology and toxicology — Posted on 2023-10-02
4554 Mutation-specific CAR T cells as precision therapy for IGLV3-21R110 expressing high-risk chronic lymphocytic leukemia
Maerkl, F.; Schultheiss, C.; Ali, M.; Chen, S.-S.; Egli, L.; Mietz, J.; Chijoke, O.; Paschold, L.; Spajic, S.; Holtermann, A.; Doerr, J.; Stock, S.; Piseddu, I.; Anz, D.; Duehren-von Minden, M.; Zhang, T.; Nerreter, T.; Hudecek, M.; Chiorazzi, N.; Kobold, S.; Binder, M.
10.1101/2023.09.29.560075 — cancer biology — Posted on 2023-10-02
4558 Pervasive GxE interactions shape adaptive trajectories and the exploration of the phenotypic space in artificial selection experiments
Desbiez-Piat, A.; Ressayre, A.; MARCHADIER, E.; Noly, A.; Remoue, C.; Vitte, C.; Belcram, H.; Bourgais, A.; Galic, N.; Le Guilloux, M.; Tenaillon, M. I.; Dillmann, C.
10.1101/2023.01.13.523786 — evolutionary biology — Posted on 2023-10-02
4560 ASB3 expression aggravates inflammatory bowel disease by targeting TRAF6 protein stability and affecting the intestinal microbiota
Cheng, M.-y.; Xu, B.; Sun, Y.; Wang, J.; Lu, Y.; Shi, C.; Pan, T.; Zhao, W.; Li, X.; Song, X.; Wang, J.; Wang, N.; Yang, W.; Jiang, Y.; Huang, H.; Yang, G.; Zeng, Y.; Yang, D.; Wang, C.; Cao, X.
10.1101/2023.07.30.551192 — immunology — Posted on 2023-10-02
4561 Remyelination protects neurons from DLK-mediated neurodegeneration
Duncan, G. J.; Ingram, S. D.; Emberley, K.; Hill, J.; Cordano, C.; Abdelhak, A.; McCane, M.; Jabassini, N.; Ananth, K.; Ferrara, S. J.; Stedelin, B.; Aicher, S. A.; Watkins, T. A.; Mishra, A.; Nelson, J.; Green, A. J.; Emery, B.
10.1101/2023.09.30.560267 — neuroscience — Posted on 2023-10-02
4563 Inhalable point-of-care urinary diagnostic platform
Zhong, Q.; Tan, E. K. W.; Martin-Alonso, C.; Parisi, T.; Hao, L.; Kirkpatrick, J. D.; Fadel, T.; Fleming, H.; Jacks, T.; Bhatia, S. N.
10.1101/2023.09.30.560328 — bioengineering — Posted on 2023-10-02
4566 Brassinosteroid recruits FERONIA to safeguard cell expansion in Arabidopsis
Chaudhary, A.; Hsiao, Y.-C.; Yeh, F.-L. J.; Wu, H.-M.; Cheung, A. Y.; Xu, S.-L.; Wang, Z.-Y.
10.1101/2023.10.01.560400 — plant biology — Posted on 2023-10-02
4567 A large-scale serological survey in pets from October 2020 through June 2021 in France shows significantly higher exposure to SARS-CoV-2 in cats
Fritz, M.; Elguero, E.; Becquart, P.; de Riols de Fonclare, D.; Garcia, D.; Beurlet, S.; Denolly, S.; Boson, B.; Rosolen, S. G.; Cosset, F.-L.; Briend-Marchal, A.; Legros, V.; Leroy, E. M.
10.1101/2022.12.23.521567 — microbiology — Posted on 2023-10-02
4568 The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic Trypanosoma brucei infection
Quintana Alcala, J. F.; Sinton, M. C.; Chandrasegaran, P.; Dubey, L. K.; Ogunsola, J.; Samman, M. A.; Haley, M.; McConnell, G.; Kuispond Swar, N. R.; Ngoyi, D. M.; Bending, D.; de Lecea, L.; MacLeod, A.; Mabbott, N. A.
10.1101/2023.04.30.538710 — immunology — Posted on 2023-10-02
4569 Stereotypic persistent B cell receptor clonotypes in Alzheimer's Disease
Yang, H.; Kim, N.; Lee, Y.; Yoo, D. K.; Choi, J.; Kim, K.; Bae, J.; Han, J.; Kwon, S.; Chung, J.
10.1101/2023.09.07.554570 — immunology — Posted on 2023-10-02
4570 COVID-19 is not associated with a putative marker of neuroinflammation: A diffusion basis spectrum imaging study.
Zhang, W.; Gorelik, A. J.; Wang, Q.; Norton, S. A.; Hershey, T.; Agrawal, A.; Bijsterbosch, J. D.; Bogdan, R.
10.1101/2023.07.20.549891 — neuroscience — Posted on 2023-10-02
4571 Analysis of ductal carcinoma in situ by self-reported race reveals molecular differences related to outcome.
Strand, S. H.; Houlahan, K. E.; Branch, V.; Lynch, T.; Harmon, B.; Couch, F.; Gallagher, K.; Kilgore, M.; Wei, S.; DeMichele, A.; King, T.; McAuliffe, P.; Curtis, C.; Owzar, K.; Marks, J. R.; Colditz, G. A.; Hwang, E. S.; West, R. B.
10.1101/2023.09.28.560000 — cancer biology — Posted on 2023-10-02
4573 CellPie: a fast spatial transcriptomics topic discovery method via joint factorization of gene expression and imaging data
Georgaka, S.; Morgans, W. G.; Zhao, Q.; Sanchez Martinez, D.; Ali, A.; Ghafoor, M.; Baker, S. M.; Bristow, R.; Iqbal, M.; Rattray, M.
10.1101/2023.09.29.560213 — bioinformatics — Posted on 2023-10-02
4574 OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion
Panagiotou, S.; Tan, K.-W.; Nguyen, P. M.; Mueller, A.; Oqua, A. I.; Tomas, A.; Wendt, A.; Eliasson, L.; Tengholm, A.; Solimena, M.; Idevall-Hagren, O.
10.1101/2023.02.22.529485 — cell biology — Posted on 2023-10-02
4579 A Sodium-dependent Trehalose Transporter Contributes to Anhydrobiosis in Insect Cell Line, Pv11
Mizutani, K.; Yoshida, Y.; Nakanishi, E.; Miyata, Y.; Tokumoto, S.; Fuse, H.; Gusev, O.; Kikuta, S.; Kikawada, T.
10.1101/2023.09.29.560116 — biochemistry — Posted on 2023-10-02
4580 Phylogenomics and ancestral reconstruction of Korarchaeota reveals genomic adaptation to habitat switching
Tahon, G.; Köstlbacher, S.; Pelve, E. A.; Baker, B. J.; Saw, J. H.; Eme, L.; Tamarit, D.; Schön, M. E.; Ettema, T. J.
10.1101/2023.09.28.559970 — microbiology — Posted on 2023-10-02
4583 Postglacial genomes from foragers across Northern Eurasia reveal prehistoric mobility associated with the spread of the Uralic and Yeniseian languages
Zeng, T. C.; Vyazov, L. M.; Kim, A.; Flegontov, P. N.; Sirak, K.; Maier, R.; Lazaridis, I.; Akbari, A.; Frachetti, M.; Tishkin, A. A.; Ryabogina, N. E.; Agapov, S. A.; Agapov, D. S.; Alekseev, A. N.; Boeskorov, G. G.; Chizhevsky, A. A.; Derevianko, A. P.; Dyakonov, V. M.; Enshin, D. N.; Fribus, A. V.; Frolov, Y. V.; Grushin, S. P.; Khokhlov, A. A.; Kitov, E. P.; Kosintsev, P.; Kovtun, I. V.; Kiryushin, K. Y.; Kiryushin, Y. F.; Makarov, N. P.; Morozov, V. V.; Nikolaev, E. N.; Rykun, M. P.; Savenkova, T. M.; Shchelchkova, M. V.; Skochina, S. N.; Shirokov, V.; Sherstobitova, O. S.; Slepchenko, S.
10.1101/2023.10.01.560332 — genomics — Posted on 2023-10-02
4585 A transmission chain linking Mycobacterium ulcerans with Aedes notoscriptus mosquitoes, possums and human Buruli ulcer cases in southeastern Australia
Mee, P. T.; Buultjens, A. H.; Oliver, J.; Brown, K.; Crowder, J. C.; Porter, J. L.; Hobbs, E. C.; Judd, L. M.; Taiaroa, G.; Puttharak, N.; Williamson, D. A.; Blasdell, K. R.; Tay, E. L.; Feldman, R.; Muzari, M. O.; Sanders, C.; Larsen, S.; Crouch, S. R.; Johnson, P. P.; Wallace, J. R.; Price, D. J.; Hoffmann, A. A.; Gibney, K. B.; Stinear, T. P.; Lynch, S. E.
10.1101/2023.05.07.539718 — microbiology — Posted on 2023-10-01
4590 A Library of Electrophysiological Responses in Plants - A Model of Transversal Education and Open Science
Madariaga, D.; Arro, D.; Irarrazaval, C.; Soto, A.; Guerra, F.; Romero, A.; Ovalle, F.; Fedrigolli, E.; DesRosiers, T.; Serbe-Kamp, E.; Marzullo, T.
10.1101/2023.09.29.560074 — plant biology — Posted on 2023-10-01
4592 Hydrophobic Clusters Direct Folding of a Synthetic Chimeric Protein
Jalan, A. A.; Hassine, L.; Romero-Romero, S.; Hübner, J.; Schweimer, K.; Höcker, B.
10.1101/2023.09.29.560087 — biophysics — Posted on 2023-10-01
4597 Reciprocal interactions between the sorghum root microbiome and the parasitic weed Striga hermonthica
Etalo, D. W.; Rybka, D.; Lombard, L.; Leite, M. F. A.; Ossowicki, A.; Dini-Andreote, F.; Arias-Giraldo, L.; Kuramae, E. E.; Crous, P. W.; Tessema, T.; Raaijmakers, J. M.
10.1101/2023.10.01.560362 — ecology — Posted on 2023-10-01
4600 HIV Infection impairs the Host Response to Mycobacterium tuberculosis Infection by altering Surfactant Protein D function in the Human Lung Alveolar Mucosa
Akhter, A.; Moliva, J.; Azad, A. K.; Olmo-Fontanez, A. M.; Garcia-Vilanova, A.; Scordo, J. M.; Gavrilin, M.; Diaz, P.; Endsley, J.; Weintraub, S.; Schlesinger, L.; Wewers, M.; Torrelles, J. B.
10.1101/2023.10.01.560171 — cell biology — Posted on 2023-10-01
4602 Amphibian mast cells: barriers to deadly chytrid fungus infections
Hauser, K. A.; Hossainey, M. R. H.; Gentry, L. K.; Garvey, C. N.; Ranganathan, N.; Kalia, N.; Yaparla, A.; Zelle, M.; Jones, E. J.; Duttargi, A. N.; Rollins-Smith, L. A.; Muletz-Wolz, C. R.; Grayfer, L.
10.1101/2023.09.29.560127 — immunology — Posted on 2023-10-01
4605 Cytomegalovirus promotes proliferation and survival of prostate cancer cells and constitutes a therapeutic target
Classon, J.; Stenudd, M.; Zamboni, M.; Alkass, K.; Eriksson, C.-J.; Pedersen, L.; Schörling, A.; Thoss, A.; Bergh, A.; Wikström, P.; Adami, H.-O.; Sorensen, H. T.; Druid, H.; Frisen, J.
10.1101/2023.10.01.560348 — cancer biology — Posted on 2023-10-01
4606 Histopathology-assisted proteogenomics provides foundations for stratification of melanoma metastases
Kuras, M.; Betancourt, L. H.; Hong, R.; Szadai, L.; Rodriguez, J.; Horvatovich, P.; Pla, I.; Eriksson, J.; Szeitz, B.; Deszcz, B.; Welinder, C.; Sugihara, Y.; Ekedahl, H.; Baldetorp, B.; Ingvar, C.; Lundgren, L.; Lindberg, H.; Oskolas, H.; Horvath, Z.; Rezeli, M.; Gil, J.; Appelqvist, R.; Kemeny, L. V.; Malm, J.; Sanchez, A.; Szasz, A. M.; Pawlowski, K.; Wieslander, E.; Fenyo, D.; Nemeth, I. B.; Marko-Varga, G.
10.1101/2023.09.29.559755 — cancer biology — Posted on 2023-10-01
4607 BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or Menin inhibitor
Fiskus, W. C.; Piel, J.; Collins, M.; Hentemann, M.; Cuglievan, B.; Mill, C. P.; Birdwell, C. E.; Das, K.; Davis, J. A.; Hou, H.; Jain, A. C.; Malovannaya, A.; Kadia, T. M.; Daver, N.; Sasaki, K.; Takahashi, K.; Hammond, D.; Reville, P. K.; Wang, J.; Loghavi, S.; Sen, R.; Ruan, X.; Su, X.; Flores, L. B.; DiNardo, C. D.; Bhalla, K. N.
10.1101/2023.09.28.560054 — cancer biology — Posted on 2023-10-01
4609 ONECUT2 Activates Diverse Resistance Drivers of Androgen Receptor-Independent Heterogeneity in Prostate Cancer
Qian, C.; Yang, Q.; Rotinen, M.; Huang, R.; Kim, h.; Gallent, B.; Yan, Y.; Cadaneanu, R. M.; Zhang, B.; Kaochar, S.; Freedland, S. J.; Posadas, E. M.; Ellis, L.; Di Vizio, D.; Morrissey, C.; Nelson, P. S.; Brady, L.; Murali, R.; Campbell, M. J.; Yang, W.; Knudsen, B. S.; Mostaghel, E. A.; Ye, H.; Garraway, I. P.; You, S.; Freeman, M. R.
10.1101/2023.09.28.560025 — cancer biology — Posted on 2023-10-01
4614 Next-generation genetic sexing strain establishment in the agricultural pest Ceratitis capitata
Davydova, S.; Liu, J.; Kandul, N. P.; Braswell, W. E.; Akbari, O. S.; Meccariello, A.
10.1101/2023.09.29.560088 — bioengineering — Posted on 2023-10-01
4616 COMPARISON OF HIGH-THROUGHPUT SINGLE-CELL RNA-SEQ METHODS FOR EX VIVO DRUG SCREENING
Gezelius, H.; Enblad, A. P.; Lundmark, A.; Aberg, M.; Blom, K.; Rudfeldt, J.; Raine, A.; Harila, A.; Rendo, V.; Heinaniemi, M.; Andersson, C.; Nordlund, J.
10.1101/2023.09.28.560069 — genomics — Posted on 2023-10-01
4620 Modeling stereospecific drug interactions with beta-adrenergic receptors
Dawson, J. R. D.; DeMarco, K. R.; Han, Y.; Bekker, S.; Clancy, C. E.; Yarov-Yarovoy, V.; Vorobyov, I.
10.1101/2023.10.01.560334 — molecular biology — Posted on 2023-10-01
4624 Integration of metabolic flux with hepatic glucagon signaling and gene expression profiles in the conscious dog
Coate, K. C.; Ramnanan, C. J.; Smith, M.; Winnick, J. J.; Kraft, G.; Irimia, J. M.; Farmer, B.; Donahue, P.; Roach, P. J.; Cherrington, A. D.; Edgerton, D. S.
10.1101/2023.09.28.559999 — physiology — Posted on 2023-10-01
4625 Nested biofabrication: Matryoshka-inspired Intra-embedded Bioprinting
Alioglu, M. A.; Yilmaz, Y. O.; Singh, Y. P.; Nagamine, M.; Celik, N.; Kim, M. H.; Pal, V.; Gupta, D.; Ozbolat, I. T.
10.1101/2023.09.28.560028 — bioengineering — Posted on 2023-10-01
4626 Integrated characterization of cell types, states and molecular programs in disseminated appendiceal neoplasms
Bui, L. T.; Cao, X.; Wang, J. T.; Meng, F.; Feng, M.; Arvanitis, L.; Mannan, R.; Woo, Y.; Idrees, K.; Banovich, N.; Raoof, M.
10.1101/2023.09.28.559817 — genomics — Posted on 2023-10-01
4630 A portable and wind resistant drift fence array for arid environments
Camper, B. T.; Laughlin, Z. T.; Kanes, A. S.; Manuel, R. T.; Bewick, S. A.
10.1101/2023.09.28.560034 — ecology — Posted on 2023-10-01
4631 Mitigation of TDP-43-induced toxic phenotype by expression of RGNEF N-terminal fragment in ALS models
Droppelmann, C. A.; Campos-Melo, D.; Noches, V.; McLellan, C.; Szabla, R.; Lyons, T.; Amzil, H.; Withers, B.; Sonkar, K.; Simon, A.; Buratti, E.; Junop, M.; Kramer, J.; Strong, M. J.
10.1101/2023.09.29.560207 — neuroscience — Posted on 2023-10-01
4632 Direct serotonin release in humans shapes decision computations within aversive environments
Colwell, M. J.; Tagomori, H.; Cheng, H.; Shang, F.; Wigg, C.; Browning, M. J.; Cowen, P. J.; Murphy, S. E.; Harmer, C. J.
10.1101/2023.09.30.560111 — neuroscience — Posted on 2023-10-01
4634 RNA virus-mediated gene editing for tomato trait breeding
Uranga, M.; Aragones, V.; Garcia, A.; Mirabel, S.; Gianoglio, S.; Presa, S.; Granell, A.; Pasin, F.; Daros, J.-A.
10.1101/2023.10.01.560115 — plant biology — Posted on 2023-10-01
4636 Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma
Li, Z.; Zhuang, X.; Pan, C.-H.; Yan, Y.; Thummalapalli, R.; Hallin, J.; Torborg, S.; Singhal, A.; Chang, J. C.; Manchado, E.; Dow, L. E.; Yaeger, R.; Christensen, J. G.; Lowe, S. W.; Rudin, C. M.; Joost, S.; Tammela, T.
10.1101/2023.09.29.560194 — cancer biology — Posted on 2023-10-01
4637 Early steps of multi-receptor viral interactions dissected by high-density, multi-color single molecule mapping in living cells
Mateos, N.; Gutierrez-Martinez, E.; Angulo-Capel, J.; Carlon-Andres, I.; Padilla-Parra, S.; Garcia-Parajo, M.; Torreno-Pina, J. A.
10.1101/2023.09.29.560105 — biophysics — Posted on 2023-10-01
4638 Microbially Driven Reversible Actuation and Color Changing Materials
Kuang, H. Y.; Bonanno, S.; Chang, W.-T.; Bower, D. Q.; Pratt, V. M.; Zerkowski, J.; Scaperdas, N.; Young, L. A.; Wilson, D. J.; Deravi, L. F.; Joshi, N. S.
10.1101/2023.09.29.560148 — bioengineering — Posted on 2023-10-01
4639 Hydrogel-Polyurethane Fiber Composites With Enhanced Microarchitectural Control For Heart Valve Replacement
Robinson, A.; Nkansah, A.; Bhat, S.; Karnik, S.; Jones, S.; Fairley, A.; Leung, J.; Wancura, M.; Sacks, M.; Dasi, L.; Cosgriff-Hernandez, E.
10.1101/2023.09.29.560202 — bioengineering — Posted on 2023-10-01
4640 Ancient genomes illuminate Eastern Arabian population history and adaptation against malaria
Martiniano, R.; Haber, M.; Almarri, M. A.; Mattiangeli, V.; Kuijpers, M. C. M.; Chamel, B.; Breslin, E. M.; Littleton, J.; Almahari, S.; Aloraifi, F.; Bradley, D. G.; Lombard, P.; Durbin, R.
10.1101/2023.10.01.559299 — genomics — Posted on 2023-10-01
4641 Bronze Age Northern Eurasian Genetics in the Context of Development of Metallurgy and Siberian Ancestry
Childebayeva, A.; Fricke, F.; Rohrlach, A. B.; Huang, L.; Schiffels, S.; Vesakoski, O.; Semerau, L.; Aron, F.; Moiseyev, V.; Khartanovich, V.; Kovtun, I.; Krause, J.; Kuzminykh, S.; Haak, W.
10.1101/2023.10.01.560195 — genetics — Posted on 2023-10-01
4642 Sex-specific DNA methylation and gene expression changes in mouse placentas after early preimplantation alcohol exposure
Legault, L.-M.; Breton-Larrivee, M.; Filion-Bienvenue, F.; Lemieux, A.; Langford-Avelar, A.; Dupas, T.; McGraw, S.
10.1101/2023.09.30.560198 — developmental biology — Posted on 2023-10-01
4646 PLASTICITY OF RESPONSE PROPERTIES OF MOUSE VISUAL CORTEX NEURONS INDUCED BY OPTOGENETIC TETANIZATION IN VIVO
Osipova, A. A.; Smirnov, I. V.; Smirnova, M. P.; Borodinova, A. A.; Volgushev, M. A.; Malyshev, A. Y.
10.1101/2023.10.01.556796 — neuroscience — Posted on 2023-10-01
4647 Transcriptional coupling of telomeric retrotransposons with the cell cycle
Liu, M.; Xie, X.-J.; Li, X.; Ren, X.; Sun, J.; Lin, Z.; Hemba-Waduge, R.- U.-S.; Ji, J.-y.
10.1101/2023.09.30.560321 — cell biology — Posted on 2023-10-01
4648 Induced pluripotent stem cell derived pericytes respond to endogenous mediators of proliferation and contractility
King, N. E.; Courtney, J.-M.; Brown, L. S.; Fortune, A. J.; Blackburn, N. B.; Fletcher, J. L.; Cashion, J. M.; Talbot, J.; Pebay, A.; Hewitt, A. W.; Morris, G. P.; Young, K. M.; Cook, A. L.; Sutherland, B. A.
10.1101/2023.09.29.560066 — cell biology — Posted on 2023-10-01
4649 HOIL-1L deficiency induces cell cycle alteration which causes immaturity of myocyte and fibrogenesis
Akagi, K.; Baba, S.; Fujita, H.; Fuseya, Y.; Yoshinaga, D.; Kubota, H.; Kume, E.; Fukumura, F.; Matsuda, K.; Tanaka, T.; Hirata, T.; Iwai, K.; Takita, J.
10.1101/2023.09.29.560255 — cell biology — Posted on 2023-10-01
4650 Interleukin 11 therapy causes acute heart failure and its use in patients should be reconsidered
Sweeney, M.; O'Fee, K.; Villanueva-Hayes, C.; Rahman, E.; Lee, M.; Maatz, H.; Lindberg, E. L.; Vanezis, K.; Andrew, I.; Jennings, E. R.; Lim, W.-W.; Widjaja, A. A.; Hübner, N.; Barton, P. J. R.; Cook, S. A.
10.1101/2023.09.30.560259 — molecular biology — Posted on 2023-10-01
4651 Extracellular vesicles from patients with coronary artery disease (CAD) demonstrate enhanced pro-coagulatory activity.
Allen-Redpath, K.; Soyama, S.; Zhou, R.; Whyte, A.; Mark, S.; Dymott, L.; Brunton, M.; Fischer, R.; Hester, S.; McKenna, C.; Ruparelia, N.; Yaqoob, P.
10.1101/2023.09.27.559865 — physiology — Posted on 2023-10-01
4654 Novel small molecules inhibit proteotoxicity and inflammation: Mechanistic and therapeutic implications for Alzheimer's Disease, healthspan and lifespan- Aging as a consequence of glycolysis
Litke, R.; Vicari, J. M.; Huang, B. T.; Roh, K.-H.; Silver, A.; Shapiro, L.; Palacios, N.; Talreja, P.; Yoon, Y.; Ramos, I.; Vangeti, S.; Kaniskan, H.; Jin, J.; Kellner, C.; Mobbs, C.
10.1101/2023.06.12.544352 — neuroscience — Posted on 2023-10-01
4656 Elasticity of the HIV-1 Core Facilitates Nuclear Entry and Infection
Deshpande, A.; Bryer, A. J.; Andino-Moncada, J. R.; Shi, J.; Hong, J.; Torres, C.; Harel, S.; Francis, A.; Perilla, J. R.; Aiken, C.; Rousso, I.
10.1101/2023.09.29.560083 — biophysics — Posted on 2023-10-01
4657 Revisiting the origins of the Sobemovirus genus: a case for ancient origins of plant viruses
Ghafari, M.; Somera, M.; Sarmiento, C.; Niehl, A.; Hebrard, E.; Tsoleridis, T.; Ball, J.; Moury, B.; Lemey, P.; Katzourakis, A.; Fargette, D.
10.1101/2023.09.29.560145 — evolutionary biology — Posted on 2023-10-01
4660 Rapid and accurate multi-phenotype imputation for millions of individuals
Gu, L.-L.; Wu, H.-S.; Zhang, Y.-J.; Liu, T.-Y.; He, J.-C.; Liu, X.-L.; Chen, G.-B.; Jiang, D.; Fang, M.
10.1101/2023.06.25.546422 — bioinformatics — Posted on 2023-10-01
4663 Genome analysis of the Jomon dogs reveals the oldest domestic dog lineage in Eastern Eurasia
Terai, Y.; Xiaokaiti, X.; Gojobori, J.; Arakawa, N.; Sato, T.; Kasai, K.; Machida, K.; Yamazaki, K.; Yamaji, N.; Hongo, H.; Gakuhari, T.
10.1101/2023.09.29.560089 — evolutionary biology — Posted on 2023-10-01
4665 Impaired BCAA catabolism during adipocyte differentiation decreases glycolytic flux
Green, C. R.; Wessendorf-Rodriguez, K. A.; Turner, R.; Hover, J. D.; Murphy, A. N.; Metallo, C. M.; Wallace, M.
10.1101/2022.05.27.493780 — cell biology — Posted on 2023-10-01
4669 Leveraging the Adolescent Brain Cognitive Development Study to improve behavioral prediction from neuroimaging in smaller replication samples
Makowski, C.; Brown, T. T.; Zhao, W.; Hagler, D. J.; Parekh, P.; Garavan, H.; Nichols, T. E.; Jernigan, T. L.; Dale, A. M.
10.1101/2023.06.16.545340 — neuroscience — Posted on 2023-10-01
4671 Cadherins orchestrate specific patterns of perisomatic inhibition onto distinct pyramidal cell populations
Jezequel, J.; Condomitti, G.; Kroon, T.; Hamid, F.; Sanalidou, S.; Garces, T.; Maeso, P.; Balia, M.; Rico, B.
10.1101/2023.09.28.559922 — neuroscience — Posted on 2023-10-01
4673 Regulation of the mouse ventral tegmental area by melanin-concentrating hormone
Spencer, C. D.; Miller, P. A.; Williams-Ikhenoba, J. G.; Nikolova, R. G.; Chee, M. J.
10.1101/2023.09.25.559435 — neuroscience — Posted on 2023-10-01
4677 AbNatiV: VQ-VAE-based assessment of antibody and nanobody nativeness for hit selection, humanisation, and engineering
Ramon, A.; Ali, M.; Atkinson, M.; Saturnino, A.; Didi, K.; Visentin, C.; Ricagno, S.; Xu, X.; Greenig, M.; Sormanni, P.
10.1101/2023.04.28.538712 — bioengineering — Posted on 2023-10-01
4678 Microinterfaces in bicontinuous hydrogelsguide rapid 3D cell migration
Xu, K. L.; Caprio, N. d.; Fallahi, H.; Dehgany, M.; Davidson, M. D.; Cheung, B. C.; Laforest, L.; Wu, M.; Shenoy, V.; Han, L.; Mauck, R. L.; Burdick, J. A.
10.1101/2023.09.28.559609 — bioengineering — Posted on 2023-10-01
4682 Toxin-mediated depletion of nicotinamide dinucleotides drives persister formation in a human pathogen
Santi, I.; Dias Teixeira, R.; Manfredi, P.; Spiess, D.; Mas, G.; Klotz, A.; Zamboni, N.; Hiller, S.; Jenal, U.
10.1101/2023.09.28.559889 — microbiology — Posted on 2023-10-01