date is 2022-05
Select an archive month  
May 2025
April 2025
March 2025
February 2025
January 2025
December 2024
November 2024
October 2024
September 2024
August 2024
July 2024
June 2024
May 2024
April 2024
March 2024
February 2024
January 2024
December 2023
November 2023
October 2023
September 2023
August 2023
July 2023
June 2023
May 2023
April 2023
March 2023
February 2023
January 2023
December 2022
November 2022
October 2022
September 2022
August 2022
July 2022
June 2022
May 2022
April 2022
March 2022
February 2022
January 2022
December 2021
November 2021
October 2021
September 2021
August 2021
July 2021
June 2021
May 2021
April 2021
March 2021
February 2021
January 2021
December 2020
November 2020
October 2020
September 2020
August 2020
July 2020
June 2020
May 2020
April 2020
March 2020
February 2020
January 2020
December 2019
November 2019
October 2019
September 2019
August 2019
July 2019
June 2019
May 2019
April 2019
March 2019
February 2019
January 2019
December 2018
November 2018
October 2018
September 2018
August 2018
July 2018
June 2018
May 2018
April 2018
March 2018
February 2018
January 2018
December 2017
November 2017
October 2017
September 2017
August 2017
July 2017
June 2017
May 2017
April 2017
March 2017
February 2017
January 2017
December 2016
November 2016
October 2016
September 2016
August 2016
July 2016
June 2016
May 2016
April 2016
March 2016
February 2016
January 2016
December 2015
November 2015
October 2015
September 2015
August 2015
July 2015
June 2015
May 2015
April 2015
March 2015
February 2015
January 2015
December 2014
November 2014
October 2014
September 2014
August 2014
July 2014
June 2014
May 2014
April 2014
March 2014
February 2014
January 2014
December 2013
November 2013

Archive, 2022-05

4 Hetero-oligomerization of TDP-43 carboxy-terminal fragments with cellular proteins contributes to proteotoxicity
Kitamura, A.; Fujimoto, A.; Kawashima, R.; Lyu, Y.; Moriya, K.; Kurata, A.; Takahashi, K.; Brielmann, R.; Bott, L. C.; Morimoto, R. I.; Kinjo, M.
10.1101/2022.05.22.493003 — molecular biology — Posted on 2022-05-31
7 BirdVox: Machine listening for bird migration monitoring
Lostanlen, V.; Cramer, A. L.; Salamon, J.; Farnsworth, A.; Van Doren, B.; Kelling, S.; Bello, J. P.
10.1101/2022.05.31.494155 — ecology — Posted on 2022-05-31
8 FBXO11 deficiency in mice impairs lung development and aggravates cigarette smoke-induced airway fibrosis
Lu, J.; Shenoy, A.; Luo, H.; Lulu, S.; Li, J. W.; Jin, Y.; Yu, Q.; Guo, S.; Shenoy, V.; Chen, H.; Bryant, A.; Wu, L.; Chang, J.; Mohammed, K.
10.1101/2022.05.31.494154 — cell biology — Posted on 2022-05-31
11 Plasma glycoproteomics delivers high-specificity disease biomarkers by detecting site-specific glycosylation abnormalities
Wessels, H. J.; Kulkarni, P.; van Dael, M.; Suppers, A.; Willems, E.; Zijlstra, F.; Kragt, E.; Gloerich, J.; Schmit, P.-O.; Pengelley, S.; Marx, K.; van Gool, A. J.; Lefeber, D. J.
10.1101/2022.05.31.494121 — molecular biology — Posted on 2022-05-31
15 Whole-genome sequencing identifies interferon induced protein IFI6 as a strong candidate gene for VNN resistance in European sea bass
Delpuech, E.; Vandeputte, M.; Morvezen, R.; Bestin, A.; Besson, M.; Brunier, J.; Bajek, A.; Imarazene, B.; Francois, Y.; Bouchez, O.; Cousin, X.; Poncet, C.; Morin, T.; Bruant, J.-S.; Chatain, B.; Haffray, P.; Phocas, F.; Allal, F.
10.1101/2022.05.31.494209 — genetics — Posted on 2022-05-31
16 Sulfate reducing bacteria associated to diatoms during a spring phytoplankton bloom
Siebers, R.; Schultz, D.; Farza, S. M.; Brauer, A.; Zuehlke, D.; Muecke, P. A.; Francis, T. B.; Bernhard, J.; Teeling, H.; Becher, D.; Riedel, K.; Urich, T.; Bengtsson, M. M.
10.1101/2022.05.31.494182 — ecology — Posted on 2022-05-31
18 HSV-1 exploits host heterochromatin for egress
Lewis, H. C.; Kelnhofer-Millevolte, L. E.; Brinkley, M. R.; Arbach, H. E.; Arnold, E. A.; Ramachandran, S.; Avgousti, D. C.
10.1101/2022.05.31.494218 — microbiology — Posted on 2022-05-31
19 Fatty acid synthesis knockdown promotes biofilm wrinkling and inhibits sporulation in Bacillus subtilis
Arjes, H. A.; Gui, H.; Porter, R.; Atolia, E.; Peters, J.; Gross, C.; Kearns, D. B.; Huang, K. A.
10.1101/2022.05.31.494136 — microbiology — Posted on 2022-05-31
20 The lupus susceptibility allele DRB1*03:01 encodes a disease-driving epitope
Miglioranza Scavuzzi, B.; van Drongelen, V.; Kaur, B.; Callahan Fox, J.; Liu, J.; Mesquita-Ferrari, R. A.; Kahlenberg, J. M.; Farkash, E. A.; Benavides, F.; Miller, F. W.; Sawalha, A.; Holoshitz, J.
10.1101/2022.05.31.494172 — immunology — Posted on 2022-05-31
21 Integration of single-cell RNA and protein data identifies novel clinically-relevant lymphocyte phenotypes in breast cancers
Al-Eryani, G.; Bartonicek, N.; Chan, C.-L.; Anderson, A.; Harvey, K.; Wu, S. Z.; Roden, D.; Wang, T.; Reeves, J.; Yeung, B. Z.; Masle-Farquhar, E.; Goodnow, C. C.; Ma, C.; Phan, T. G.; Lundeberg, J.; Junankar, S.; Swarbrick, A.
10.1101/2022.05.31.494081 — immunology — Posted on 2022-05-31
22 Physical and functional convergence of the autism risk genes Scn2a and Ank2 in neocortical pyramidal cell dendrites
Nelson, A. D.; Catalfio, A. M.; Gupta, J. M.; Min, L.; Caballero-Floran, R. N.; Dean, K. P.; Elvira, C. C.; Derderian, K. D.; Kyoung, H.; Sahagun, A.; Sanders, S. J.; Bender, K.; Jenkins, P. M.
10.1101/2022.05.31.494205 — neuroscience — Posted on 2022-05-31
23 A remodeled RNA polymerase II complex catalyzing viroid RNA-templated transcription
Dissanayaka Mudiyanselage, S. D.; Ma, J.; Pechan, T.; Pechanove, O.; Liu, B.; Wang, Y.
10.1101/2022.05.31.494195 — plant biology — Posted on 2022-05-31
24 Mast cells impair melanoma cell homing and metastasis by inhibiting HMGA1 secretion.
Benito-Martin, A.; Hergueta-Redondo, M.; Nogues, L.; Castellano-Sanz, E.; Garvin, E.; Cioffi, M.; Sola-Castrillo, P.; Buehring, W.; Ximenez-Embun, M. P.; Munoz, J.; Matei, I.; Villanueva, J.; Peinado, H.
10.1101/2022.05.31.494113 — cancer biology — Posted on 2022-05-31
25 Structure-based discovery of selective histone deacetylase (HDAC) 3 and 4 inhibitors
Agarwal, R.; Pattarawat, P.; Duff, M. R.; Wang, H.-C. R.; Baudry, J.; Smith, J.
10.1101/2022.05.31.494169 — cancer biology — Posted on 2022-05-31
30 SARS-CoV-2 impacts the transcriptome and epigenome at the maternal-fetal interface in pregnancy
Gao, L.; Mathur, V.; Tam, S. K. M.; Zhou, X.; Cheung, M. F.; Chan, L. Y.; Estrada-Gutierrez, G.; Leung, B. W.; Moungmaithong, S.; Wang, C. C.; Poon, L.; Leung, D. C. Y.
10.1101/2022.05.31.494153 — genomics — Posted on 2022-05-31
31 Comprehensive characterization of the transcriptional response to COVID-19 in multiple organs reveals shared signatures across tissues
The COVID Tissue Atlas Consortium, ; Granados, A. A.; Bucher, S.; Agrawal, A.; Song, H.; Chen, A. T.; Peng, T.; Neff, N.; Pisco, A. O.; Huang, F.; Wang, B.
10.1101/2022.05.31.493925 — genomics — Posted on 2022-05-31
33 Single nuclei transcriptomics of muscle reveals intra-muscular cell dynamics linked to dystrophin loss and rescue
Scripture-Adams, D. D.; Chesmore, K. N.; Barthelemy, F.; Wang, R. T.; Nieves-Rodriguez, S.; Wang, D. W.; Mokhonova, E. I.; Douine, E. D.; Wan, J.; Little, I.; Rabichow, L. N.; Nelson, S. F.; Miceli, M. C.
10.1101/2022.05.31.494197 — genetics — Posted on 2022-05-31
34 Within-patient evolution of plasmid-mediated antimicrobial resistance
DelaFuente, J.; Toribio-Celestino, L.; Santos-Lopez, A.; Leon-Sampedro, R.; Aida Alonso-del Valle, A.; Costas, C.; Hernandez-Garcia, M.; Cui, L.; Rodriguez-Beltran, J.; Bikard, D.; Canton, R.; San Millan, A.
10.1101/2022.05.31.493991 — evolutionary biology — Posted on 2022-05-31
39 The mIAA7 degron improves auxin-mediated degradation in C. elegans
Sepers, J. J.; Verstappen, N. H. M.; Vo, A. A.; Ragle, J. M.; Ruijtenberg, S.; Ward, J. D.; Boxem, M.
10.1101/2022.05.31.494192 — molecular biology — Posted on 2022-05-31
49 The dynseq genome browser track enables visualization of context-specific, dynamic DNA sequence features at single nucleotide resolution
Nair, S.; Barrett, A.; Li, D.; Raney, B. J.; Lee, B. T.; Kerpedjiev, P.; Ramalingam, V.; Pampari, A.; Lekschas, F.; Wang, T.; Haeussler, M.; Kundaje, A.
10.1101/2022.05.26.493621 — genomics — Posted on 2022-05-31
50 Cost-efficient whole genome-sequencing using novel mostly natural sequencing-by-synthesis chemistry and open fluidics platform
Almogy, G.; Pratt, M.; Oberstrass, F.; Lee, L.; Mazur, D.; Beckett, N.; Barad, O.; Soifer, I.; Perelman, E.; Etzioni, Y.; Sosa, M.; Jung, A.; Clark, T.; Lithwick-Yanai, G.; Pollock, S.; Hornung, G.; Levy, M.; Coole, M.; Howd, T.; Shand, M.; Farjoun, Y.; Emery, J.; Hall, G.; Lee, S. K.; Sato, T.; Magner, R.; Low, S.; Bernier, A.; Gandi, B.; Stohlman, J.; Nolet, C.; Donovan, S.; Blumenstiel, B.; Cipicchio, M.; Dodge, S.; Banks, E.; Lennon, N.; Gabriel, S.; Lipson, D.
10.1101/2022.05.29.493900 — genomics — Posted on 2022-05-31
51 Precipitation is the main axis of tropical phylogenetic turnover across space and time
Ringelberg, J. J.; Koenen, E. J. M.; Sauter, B.; Aebli, A.; Rando, J. G.; Iganci, J. R.; de Queiroz, L. P.; Murphy, D. J.; Gaudeul, M.; Bruneau, A.; Luckow, M.; Lewis, G. P.; Miller, J. T.; Simon, M. F.; Jordao, L. S. B.; Morales, M.; Bailey, C. D.; Nageswara-Rao, M.; Loiseau, O.; Pennington, R. T.; Dexter, K. G.; Zimmermann, N. E.; Hughes, C. E.
10.1101/2022.05.27.493777 — evolutionary biology — Posted on 2022-05-31
53 SMAD4 and TGFβ are architects of inverse genetic programs during fate-determination of antiviral memory CD8 T cells
Chandiran, K.; Suarez-Ramirez, J.; Hu, Y.; Ugur, Z.; Jellison, E. R.; low, J.-S.; McDonald, B.; Kaech, S. M.; Cauley, L. S.
10.1101/2021.12.16.472993 — immunology — Posted on 2022-05-31
54 Masked features of task states found in individual brain networks
Porter, A.; Nielsen, A. M.; Dorn, M.; Dworetsky, A.; Edmonds, D.; Gratton, C.
10.1101/2021.06.12.448198 — neuroscience — Posted on 2022-05-31
59 Crowding induced morphological changes in synthetic lipid vesicles determined using smFRET
Quinn, S. D.; Shepherd, J.; Dresser, L.; Graham, S.; Conteduca, D.; Leake, M. C.
10.1101/2022.05.31.494132 — biophysics — Posted on 2022-05-31
62 Gene editing and super-resolution microscopy reveal multiple distinct roles for ARF GTPases in cellular membrane organization
Wong-Dilworth, L.; Rodilla-Ramirez, C.; Fox, E.; Restel, S. D.; Stockhammer, A.; Adarska, P.; Bottanelli, F.
10.1101/2022.05.31.494106 — cell biology — Posted on 2022-05-31
63 Adipose-derived stromal cells preserve pancreatic islet function in a transplantable 3D bioprinted scaffold
Abadpour, S.; Niemi, E. M.; Orrhult, L. S.; Hermanns, C.; de Vries, R.; Nogueira, L. P.; Haugen, H. J.; Josefsen, D.; Krauss, S.; van Apeldoorn, A.; Gatenholm, P.; Scholz, H.
10.1101/2022.05.30.494035 — cell biology — Posted on 2022-05-31
65 Potent and pan-neutralization of SARS-CoV-2 variants of concern by DARPins
Chonira, V. K.; Kwon, Y.-D.; Gorman, J.; Case, J. B.; Ku, Z.; Simeon, R.; Casner, R. G.; Harris, D. R.; Olia, A. S.; Stevens, T.; Shapiro, L.; Boyd, H.; Tsybovsky, Y.; Krammer, F.; Diamond, M.; Kwong, P. D.; An, Z.; Chen, Z.
10.1101/2022.05.30.493765 — bioengineering — Posted on 2022-05-31
67 The IFT81-IFT74 complex enhances GTP hydrolysis to inactivate RabL2 during early steps of intraflagellar transport
Boegholm, N.; Petriman, N. A.; Loureiro-Lopez, M.; Kanie, T.; Jackson, P. K.; Andersen, J. S.; Lorentzen, E.
10.1101/2022.05.31.494111 — biochemistry — Posted on 2022-05-31
70 A Chloroplast Protein Atlas Reveals Novel Structures and Spatial Organization of Biosynthetic Pathways
Wang, L.; Patena, W.; Van Baalen, K. A.; Xie, Y.; Singer, E. R.; Gavrilenko, S.; Warren-Williams, M.; Han, L.; Harrigan, H. R.; Chen, V.; Ton, V. T. N. P.; Kyin, S.; Shwe, H. H.; Cahn, M. H.; Wilson, A. T.; Hu, J.; Schnell, D. J.; McWhite, C. D.; Jonikas, M.
10.1101/2022.05.31.493820 — plant biology — Posted on 2022-05-31
71 Persistent Inflammatory Lipotoxicity Impedes Pancreatic β-cell Function in Diet-Induced Obese Mice Despite Correction of Glucotoxicity
Valdez, I. A.; Palavicini, J. P.; Bakewell, T. M.; Fourcaudot, M.; Ayala, I.; Xu, Z.; Khattab, A.; Han, X.; Shannon, C. E.; Norton, L.
10.1101/2022.05.31.494168 — physiology — Posted on 2022-05-31
72 The ERK5/NF-κB signaling pathway targets endometrial cancer proliferation and survival
Dieguez-Martinez, N.; Espinosa-Gil, S.; Yoldi, G.; Megias-Roda, E.; Bolinaga-Ayala, I.; Vinas-Casas, M.; Domingo-Orti, I.; Perez-Montoyo, H.; Bayascas, J. R.; Colas, E.; Dolcet, X.; Lizcano, J. M.
10.1101/2022.05.31.494135 — cancer biology — Posted on 2022-05-31
74 Multiomic deep delve of synthesis and secretion processes in a model peptidergic system
Barez-Lopez, S.; Mecawi, A. S.; Bryan, N.; Gillard, B. T.; Pauza, A. G.; Murphy, D.; Greenwood, M. P.
10.1101/2022.05.31.494122 — neuroscience — Posted on 2022-05-31
82 Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells
Petrelli, F.; Scandella, V.; Montessuit, S.; Zamboni, N.; Martinou, J.-C.; Knobloch, M.
10.1101/2022.05.31.494137 — cell biology — Posted on 2022-05-31
83 Double trouble or a blessing in disguise? Co-infection of potato with the causal agents of late and early blight
Brouwer, S. M.; Wolters, P. J.; Andreasson, E.; Liljeroth, E.; Vleeshouwers, V. G. A. A.; Grenville-Briggs, L. J.
10.1101/2022.05.31.494103 — microbiology — Posted on 2022-05-31
89 Spontaneous Variations in Arousal Modulate Subsequent Visual Processing and Local Field Potential Dynamics in the Ferret during Quiet Wakefulness
Klaver, L. M. F.; Brinkhof, L. P.; Sikkens, T.; Casado-Roman, L.; Williams, A. G.; van Mourik-Donga, L.; Mejias, J. F.; Pennartz, C. M. A.; Bosman, C. A.
10.1101/2022.05.31.494160 — neuroscience — Posted on 2022-05-31
93 The complex octoploid Craterostigma genome and tissue-specific mechanisms underlying desiccation tolerance
VanBuren, R.; Wai, C. M.; Giarola, V.; Zupunski, M.; Pardo, J.; Kalinowski, M.; Grossmann, G.; Bartels, D.
10.1101/2022.05.31.494158 — plant biology — Posted on 2022-05-31
94 T Cell-to-Stroma Enrichment (TSE) score: a gene expression metric that predicts response to immune checkpoint inhibitors in patients with urothelial cancer
Rijnders, M. M.; Nakauma-Gonzalez, J. A.; Robbrecht, D. G. J.; Gil-Jimenez, A.; Aarts, M. J. B.; Boormans, J. L.; Hamberg, P.; van der Heijden, M. S.; Szabados, B. E.; van Leenders, G. J. L. H.; Mehra, N.; Voortman, J.; Westgeest, H. M.; de Wit, R.; van der Veldt, A. A. M.; Debets, R.; Lolkema, M. P.
10.1101/2022.05.30.493997 — cancer biology — Posted on 2022-05-31
96 Pharmacological PP2A reactivation overcomes multikinase inhibitor tolerance across brain tumor cell models
Denisova, O.; Merisaari, J.; Huhtaniemi, R.; Qiao, X.; Kaur, A.; Yetukuri, L.; Jumppanen, M.; Paakkonen, M.; von Schantz-Fant, C.; Ohlmeyer, M.; Wennerberg, K.; Kauko, O.; Koch, R.; Aittokallio, T.; Taipale, M.; Westermarck, J.
10.1101/2022.05.31.494146 — cancer biology — Posted on 2022-05-31
97 Internally-controlled and dynamic optical measures of functional tumor biology
Chung, T.; Garcia, L.; Swamynathan, M. M.; Froeling, F. E. M.; Trotman, L. C.; Tuveson, D. A.; Lyons, S. K.
10.1101/2022.05.30.493733 — cancer biology — Posted on 2022-05-31
100 vsRNAfinder: a novel method for identifying high-confidence viral small RNAs from small RNA-Seq data
Cai, Z.; Fu, P.; Qiu, Y.; Wu, A.; Zhang, G.; Wang, Y.; Jiang, T.; Ge, X.; Zhu, H.; Peng, Y.
10.1101/2022.05.30.493989 — bioinformatics — Posted on 2022-05-31
104 DrDimont: Explainable drug response predictionfrom differential analysis of multi-omics networks
Hiort, P.; Hugo, J.; Zeinert, J.; Müller, N.; Kashyap, S.; Rajapakse, J. C.; Azuaje, F.; Renard, B. Y.; Baum, K.
10.1101/2022.05.31.493964 — bioinformatics — Posted on 2022-05-31
106 Multicellular Aligned Bands Disrupt Global Collective Cell Behavior
Jebeli, M.; Lopez, S. K.; Goldblatt, Z. E.; McCollum, D.; Mana-Capelli, S.; Wen, Q.; Billiar, K.
10.1101/2022.05.30.494066 — bioengineering — Posted on 2022-05-31
108 Rapid and in-depth coverage of the (phospho-)proteome with deep libraries and optimal window design for dia-PASEF
Skowronek, P.; Thielert, M.; Voytik, E.; Tanzer, M. C.; Hansen, F. M.; Willems, S.; Karayel, O.; Brunner, A.-D.; Meier, F.; Mann, M.
10.1101/2022.05.31.494163 — biochemistry — Posted on 2022-05-31
112 Leveraging a natural murine meiotic drive to suppress invasive populations
Gierus, L.; Birand, A.; Bunting, M. D.; Godahewa, G. I.; Piltz, S. G.; Oh, K. P.; Piaggio, A. J.; Threadgill, D. W.; Godwin, J.; Edwards, O.; Cassey, P.; Ross, J. V.; Prowse, T. A. A.; Thomas, P. Q.
10.1101/2022.05.31.494104 — genetics — Posted on 2022-05-31
114 Delineating antibody escape from Omicron sublineages
Gruell, H.; Vanshylla, K.; Korenkov, M.; Tober-Lau, P.; Zehner, M.; Muenn, F.; Janicki, H.; Augustin, M.; Schommers, P.; Sander, L. E.; Kurth, F.; Kreer, C.; Klein, F.
10.1101/2022.04.06.487257 — immunology — Posted on 2022-05-31
117 Conserved transcriptional programming across sex and species after peripheral nerve injury predicts treatments for neuropathic pain
Ghazisaeidi, S.; Muley, M. M.; Tu, Y.; Kolahdouzan, M.; Sengar, A. S.; Ramani, A. K.; Brudno, M.; Salter, M. W.
10.1101/2022.05.30.494054 — neuroscience — Posted on 2022-05-31
121 Spatially Resolved Metabolites in Stable and Vulnerable Human Atherosclerotic Plaques Identified by Mass Spectrometry Imaging
Seeley, E. H.; Liu, Z.; Yuan, S.; Stroope, C.; Cockerham, E. D.; Rashdan, N.; Finney, A. C.; Kumar, D.; Das, S.; Razani, B.; Liu, W.; Traylor, J. G.; Rom, O.; Pattillo, C. B.; Yurdagul, A.
10.1101/2022.05.30.494038 — pathology — Posted on 2022-05-31
125 Natural selection and the advantage of recombination
Gerrish, P. J.; Galeota-Sprung, B.; Cordero, F.; Sniegowski, P. D.; Colato, A.; Hengartner, N. W.; Vejalla, V.; Chevalier, J.; Ycart, B.
10.1101/2020.08.28.271486 — evolutionary biology — Posted on 2022-05-31
127 Novel functions of Kaposi's sarcoma herpesvirus viral FLICE inhibitory protein
Herold, K.; Ruffin, A.; Moorad, R.; Constantine, M.; Causey, A.; Mitchell, A. E.; Chmura, J. C.; Ehrlich, E. S.
10.1101/629113 — microbiology — Posted on 2022-05-31
128 Transient regulation of focal adhesion via Tensin3 is required for nascent oligodendrocyte differentiation
Merour, E.; Hmidan, H.; Marie, C.; Helou, P.-H.; Lu, H.; Potel, A.; Hure, J.-B.; Clavairoly, A.; Shih, Y. P.; Goudarzi, S.; Dussaud, S.; Ravassard, P.; Hafizi, S.; Lo, S. H.; Hassan, B. A.; Parras, C.
10.1101/2022.02.25.481980 — neuroscience — Posted on 2022-05-31
131 Crowding induced morphological changes in synthetic lipid vesicles determined using smFRET
Quinn, S. D.; Shepherd, J.; Dresser, L.; Graham, S.; Conteduca, D.; Leake, M. C.
10.1101/2022.05.31.494132 — biophysics — Posted on 2022-05-31
132 Prediction of Kv11.1 potassium channel PAS-domain variants trafficking via machine learning
Immadisetty, K.; Fang, X.; Hartle, C. M.; McCoy, T. P.; Mirshahi, T.; Delisle, B. P.; Kekenes-Huskey, P.
10.1101/2021.11.03.467212 — bioinformatics — Posted on 2022-05-31
133 Within-individual changes reveal increasing social selectivity with age in rhesus macaques
Siracusa, E. R.; Negron-Del Valle, J. E.; Phillips, D.; Platt, M.; Higham, J. P.; Snyder-Mackler, N.; Brent, L. J. N.
10.1101/2022.05.31.494118 — animal behavior and cognition — Posted on 2022-05-31
135 Oligomerization processes limit photoactivation and recovery of the Orange Carotenoid Protein.
Andreeva, E. A.; Nizinski, S.; Wilson, A.; Levantino, M.; De Zitter, E.; Munro, R.; Muzzopappa, F.; Thureau, A.; Zala, N.; Burdzinski, G.; Sliwa, M.; Kirilovsky, D.; Schiro, G.; Colletier, J.-P.
10.1101/2022.02.04.479168 — biophysics — Posted on 2022-05-31
136 Impact of crowding on the diversity of expanding populations
Schreck, C. F.; Fusco, D.; Karita, Y.; Martis, S.; Kayser, J.; Duvernoy, M.-C.; Hallatschek, O.
10.1101/743534 — evolutionary biology — Posted on 2022-05-31
138 Natural selection promotes the evolution of recombination 2: during the process of natural selection
Gerrish, P. J.; Cordero, F.; Galeota-Sprung, B.; Colato, A.; Vejalla, V.; Sniegowski, P. D.; Hengartner, N. W.
10.1101/2021.06.07.447324 — evolutionary biology — Posted on 2022-05-31
140 Genomic surveillance of carbapenem-resistant Klebsiella in Wales reveals persistent spread of K. pneumoniae ST307 and adaptive evolution of pOXA-48-like plasmids
David, S.; Mentasti, M.; Sands, K.; Portal, E.; Graham, L.; Watkins, J.; Williams, C.; Healy, B.; Spiller, O. B.; Aanensen, D.; Wootton, M.; Jones, L. S.
10.1101/2022.05.25.492139 — microbiology — Posted on 2022-05-31
147 An affinity-matured DLL4 ligand for broad-spectrum activation and inhibition of Notch signaling
Gonzalez-Perez, D.; Das, S.; Medina, E.; Antfolk, D.; Egan, E. D.; Blacklow, S. C.; Rodriguez, P. C.; Luca, V. C.
10.1101/2022.03.07.483330 — bioengineering — Posted on 2022-05-31
148 Determinants of hyena participation in risky collective action
Montgomery, T. M.; Lehmann, K. D. S.; Gregg, S.; Keyser, K.; McTigue, L. E.; Beehner, J. C.; Holekamp, K. E.
10.1101/2022.05.30.494003 — animal behavior and cognition — Posted on 2022-05-31
149 Gene expression and RNA splicing explain large proportions of the heritability for complex traits in cattle
Xiang, R.; Fang, L.; Liu, S.; Macleod, I.; Liu, Z.; Breen, E.; Gao, Y.; Liu, G.; Tenesa, A.; Mason, B.; Chamberlain, A.; Wray, N. R.; Goddard, M.
10.1101/2022.05.30.494093 — genomics — Posted on 2022-05-31
150 Specificity and overlap in the genetic architectures of functional and structural connectivity within cerebral resting-state networks
Tissink, E.; Werme, J.; de Lange, S. C.; Savage, J. E.; Wei, Y.; de Leeuw, C. A.; Nagel, M.; Posthuma, D.; van den Heuvel, M. P.
10.1101/2022.05.31.494125 — genetics — Posted on 2022-05-31
155 HAPLN1 is a driver for peritoneal carcinomatosis in pancreatic cancer
Wiedmann, L.; De Angelis Rigotti, F.; Vaquero-Siguero, N.; Donato, E.; Espinet, E.; Moll, I.; Alsina-Sanchis, E.; Mülfarth, R.; Vacca, M.; Gerwing, J.; Trumpp, A.; Fischer, A.; Rodriguez-Vita, J.
10.1101/2022.05.30.493185 — cancer biology — Posted on 2022-05-31
157 HAPLN1 is a driver for peritoneal carcinomatosis in pancreatic cancer
Wiedmann, L.; De Angelis Rigotti, F.; Vaquero-Siguero, N.; Donato, E.; Espinet, E.; Moll, I.; Alsina-Sanchis, E.; Mülfarth, R.; Vacca, M.; Feufel, J. E.; Trumpp, A.; Fischer, A.; Rodriguez-Vita, J.
10.1101/2022.05.30.493185 — cancer biology — Posted on 2022-05-31
159 Retinoic acid signaling modulation guides in vitro specification of human heart field-specific progenitor pools
Zawada, D.; Kornherr, J.; Meier, A. B.; Santamaria, G.; Dorn, T.; Ortmann, D.; Lachmann, M.; Ortiz, M.; Harmer, S. C.; Nobles, M.; Tinker, A.; Pedersen, R. A.; Grote, P.; Laugwitz, K.-L.; Moretti, A.; Goedel, A.
10.1101/2022.05.30.494027 — cell biology — Posted on 2022-05-30
160 Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities
Zhang, Y.; Remillard, D.; Onubogu, U.; Karakyriakou, B.; Asiaban, J. N.; Ramos, A. R.; Bowland, K.; Bishop, T. R.; Ott, C. J.; Janiszewska, M.; Cravatt, B. F.; Erb, M. A.
10.1101/2022.05.30.493851 — cancer biology — Posted on 2022-05-30
161 Haplotype-phased and chromosome-level assembly of Puccinia polysora, a giga-scale fungal pathogen causing southern corn rust
Liang, J.; Li, Y.; Dodds, P. N.; Figueroa, M.; Sperschneider, J.; Han, S.; Tsui, C. K. M.; Zhang, K.; Li, L.; Ma, Z.; Cai, L.
10.1101/2022.05.18.492400 — genomics — Posted on 2022-05-30
164 Modified methods for bovine sperm RNA isolation for consistent quality and RNA yield
Dewry, R. K.; Mohanty, T. K.; Nath, S.; Bhakat, M.; Yadav, H. P.; Baithalu, R. K.
10.1101/2022.05.30.493985 — molecular biology — Posted on 2022-05-30
168 Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages
Li, X.; Pan, Y.; Yin, Q.; Wang, Z.; Shan, S.; Zhang, L.; Yu, J.; Qu, Y.; Sun, L.; Gui, F.; Lu, J.; Jing, Z.; Wu, W.; Huang, T.; Shi, X.; Li, J.; Li, X.; Li, D.; Wang, S.; Yang, M.; Zhang, L.; Duan, K.; Liang, M.; Yang, X.; Wang, X.
10.1101/2022.05.27.493682 — biochemistry — Posted on 2022-05-30
170 ZBP1 sequesters cGAS in the cytoplasm and sustains type I interferon responses to mitochondrial DNA
Lei, Y.; Vanportfliet, J. J.; Chen, Y.-F.; Bryant, J. D.; Ragan, K. B.; Tong, C. W.; West, L. C.; Bosenberg, M. W.; Li, P.; Shadel, G. S.; Upton, J. W.; West, A. P.
10.1101/2022.05.30.493783 — immunology — Posted on 2022-05-30
173 Ultra high-throughput whole-genome methylation sequencing reveals trajectories in precancerous polyps to early colorectal adenocarcinoma
Lee, H.; Krieger, G.; Clark, T.; Khan, A.; Hanson, C. R.; Zhu, Y.; Bararpour, N.; Horning, A. M.; Esplin, E. D.; Nevins, S.; Weimer, A. K.; Meiri, E.; Gilad, S.; Benjamin, S.; Lebanony, D.; Iremadze, N.; Oberstraas, F.; Jaimovich, A.; Greenleaf, W.; Ford, J. M.; Lipson, D.; Shipony, Z.; Snyder, M.
10.1101/2022.05.30.494076 — genomics — Posted on 2022-05-30
174 Molecular consequences of PQBP1 deficiency, involved in the X-linked Renpenning syndrome
Courraud, J.; Engel, C.; Quartier, A.; Drouot, N.; Houessou, U.; Plassard, D.; Sorlin, A.; Brischoux-Boucher, E.; Van Maldergem, L.; Gouy, E.; Rossi, M.; Edery, P.; Putoux, A.; Gilbert-Dussardier, B.; Kalscheuer, V.; Mandel, J.-L.; Piton, A.
10.1101/2022.05.29.493091 — genetics — Posted on 2022-05-30
175 Chromatin remodeler Chd7 regulates photoreceptor development and outer segment length
Krueger, L. A.; Bills, J. D.; Lim, Z. Y.; Skidmore, J. M.; Martin, D. M.; Morris, A. C.
10.1101/2022.05.30.494019 — developmental biology — Posted on 2022-05-30
176 Flat Clathrin Lattices Nucleate Reticular Adhesions in an Integrin β1 Activity-Dependent Manner
Hakanpaa, L.; Abouelezz, A.; Lenaerts, A.-S.; Algie, M.; Barlund, J.; Katajisto, P.; McMahon, H. T.; Almeida-Souza, L.
10.1101/2022.05.30.494022 — cell biology — Posted on 2022-05-30
179 ZBP1 sequesters cGAS in the cytoplasm and sustains type I interferon responses to mitochondrial DNA
Lei, Y.; Vanportfliet, J. J.; Chen, Y.-F.; Bryant, J. D.; Ragan, K. B.; Tong, C. W.; West, L. C.; Bosenberg, M. W.; Li, P.; Shadel, G. S.; Upton, J. W.; West, A. P.
10.1101/2022.05.30.493783 — immunology — Posted on 2022-05-30
180 Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing
Kessler, N.; Viehmann, S. F.; Krollmann, C.; Mai, K.; Kirschner, K. M.; Luksch, H.; Kotagiri, P.; Boehner, A. M. C.; Huugen, D.; de Oliveira Mann, C. C.; Otten, S.; Weiss, S. A. I.; Zillinger, T.; Dobrikova, K.; Jenne, D. E.; Ablasser, A.; Bartok, E.; Hartmann, G.; Hopfner, K.-P.; Lyons, P. A.; Boor, P.; Roesen-Wolff, A.; Teichmann, L.; Heeringa, P.; Kurts, C.; Garbi, N.
10.1101/2022.05.30.493983 — immunology — Posted on 2022-05-30
182 Elicitors of plant defense induce the accumulation of amino acids that suppress both bacterial virulence and growth
Zhang, X.; Tubergen, P. J.; Agorsor, I.; Khadka, P.; Tempe, C.; Collakova, E.; Pilot, G.; Danna, C. H.
10.1101/2022.05.30.494047 — plant biology — Posted on 2022-05-30
185 HAPLN1 is a driver for peritoneal carcinomatosis in pancreatic cancer
Wiedmann, L.; De Angelis Rigotti, F.; Vaquero-Siguero, N.; Donato, E.; Espinet, E.; Moll, I.; Alsina-Sanchis, E.; Mülfarth, R.; Vacca, M.; Feufel, J. E.; Trumpp, A.; Fischer, A.; Rodriguez-Vita, J.
10.1101/2022.05.30.493185 — cancer biology — Posted on 2022-05-30
195 The Network Zoo: a multilingual package for the inference and analysis of biological networks
Guebila, M. B.; Wang, T.; Lopes-Ramos, C. M.; Fanfani, V.; Weighill, D.; Burkholz, R.; Schlauch, D.; Paulson, J. N.; Altenbuchinger, M.; Sonawane, A.; Lim, J.; Calderer, G.; van Ijzendoorn, D.; Morgan, D.; Marin, A.; Chen, C.-Y.; Song, A.; Shutta, K.; DeMeo, D.; Padi, M.; Platig, J.; Kuijjer, M. L.; Glass, K.; Quackenbush, J.
10.1101/2022.05.30.494077 — genomics — Posted on 2022-05-30
198 Resource competition predicts assembly of in vitro gut bacterial communities
Ho, P.-Y.; Nguyen, T. H.; Sanchez, J. M.; DeFelice, B. C.; Huang, K. C.
10.1101/2022.05.30.494065 — ecology — Posted on 2022-05-30
199 The SARS-CoV-2 accessory factor ORF7a downregulates MHC class I surface expression
Zheng, S.; de Buhr, H.; Praest, P.; Evers, A.; Brak Boer, I.; van Grinsven, M.; Longo, Y.; de Vries, L.; Nijenhuis, W.; Kapitein, L. C.; Beekman, J. M.; Nijhuis, M.; Drexler, I.; Wiertz, E. J.; Lebbink, R. J.
10.1101/2022.05.29.493850 — microbiology — Posted on 2022-05-30
200 Development of the Intestinal Microbiome in Cystic Fibrosis in Early Life
Price, C. E.; Hampton, T. H.; Valls, R.; Barrack, K.; O'Toole, G.; Madan, J. C.; Coker, M.
10.1101/2022.05.27.493808 — microbiology — Posted on 2022-05-30
202 T cell Egress via Lymphatic Vessels Limits the Intratumoral T cell Repertoire in Melanoma
Steele, M. M.; Dryg, I. D.; Murugan, D.; Femel, J.; du Bois, H.; Hill, C.; Leachman, S. A.; Chang, Y. H.; Coussens, L. M.; Lund, A. W.
10.1101/2022.05.30.494080 — immunology — Posted on 2022-05-30
203 Generation of Functional Human T Cell Development in NOD/SCID/IL2rγnull Humanized Mice Without Using Fetal Tissue: Application as a Model of HIV Infection and Persistence
Colas, C.; Volodina, O.; Beland, K.; Pham, T. N. Q.; Li, Y.; Dallaire, F.; Soulard, C.; Lemieux, W.; Colamartino, A.; Tremblay-Laganiere, C.; Dicaire, R.; Guimond, J.; Patey, N.; Vobecky, S.; Poirier, N.; Cohen, E. A.; Haddad, E.
10.1101/2022.05.30.494009 — immunology — Posted on 2022-05-30
204 Surface-based tracking for short association fibre tractography
Shastin, D.; Genc, S.; Parker, G. D.; Koller, K.; Tax, C. M. W.; Evans, J.; Hamandi, K.; Gray, W. P.; Jones, D. K.; Chamberland, M.
10.1101/2021.05.07.443084 — neuroscience — Posted on 2022-05-30
206 A Role for Steroid 5 alpha-reductase 1 in Vascular Remodelling During Endometrial Decidualisation
Shaw, I. W.; Kirkwood, P. M.; Rebourcet, D.; Cousins, F. L.; Ainslie, R. J.; Livingstone, D. E. W.; Smith, L. B.; Saunders, P. T. K.; Gibson, D. A.
10.1101/2022.05.30.493728 — physiology — Posted on 2022-05-30
207 KIF1A is kinetically tuned to be a super-engaging motor under hindering loads
Pyrpassopoulos, S.; Gicking, A. M.; Zaniewski, T. M.; Hancock, W. O.; Ostap, E. M.
10.1101/2022.05.16.492183 — biophysics — Posted on 2022-05-30
209 Adipocyte autophagy limits gut inflammation by controlling oxylipin levels
Richter, F. C.; Friedrich, M.; Kampschulte, N.; Pohin, M.; Alsaleh, G.; Guschina, I.; Wideman, S. K.; Johnson, E.; Borsa, M.; Piletic, K.; Hahn, P.; Schipper, H. S.; Edwards, C.; Zechner, R.; Schebb, N. H.; Powrie, F.; Simon, A. K.
10.1101/2021.10.25.465200 — immunology — Posted on 2022-05-30
210 The lncRNA Firre functions as a transcriptional activator from a distance
Much, C.; Lasda, E.; Lewandowski, J.; Smallegan, M. J.; Rinn, J. L.
10.1101/2022.05.15.492001 — genomics — Posted on 2022-05-30
211 Machine-learning dissection of Human Accelerated Regions in primate neurodevelopment
Whalen, S.; Inoue, F.; Ryu, H.; Fair, T.; Markenscoff-Papadimitriou, E.; Keough, K.; Kircher, M.; Martin, B.; Alvarado, B.; Elor, O.; Cintron, D. L.; Williams, A.; Samee, M. A. H.; Thomas, S.; Krencik, R.; Ullian, E.; Kriegstein, A.; Shendure, J.; Pollen, A.; Ahituv, N.; Pollard, K.
10.1101/256313 — evolutionary biology — Posted on 2022-05-30
214 Mitochondrially targeted proximity biotinylation and proteomic analysis in Plasmodium falciparum
Lamb, I. M.; Rios, K. T.; Shukla, A.; Ahiya, A. I.; Morrisey, J. M.; Mell, J. C.; Lindner, S. E.; Mather, M. W.; Vaidya, A. B.
10.1101/2022.05.30.494025 — microbiology — Posted on 2022-05-30
215 The virtual aging brain: a model-driven explanation for cognitive decline in older subjects
Lavanga, M.; Stumme, J.; Yalcinkaya, B. H.; Fousek, J.; Jockwitz, C.; Sheheitli, H.; Bittner, N.; Hashemi, M.; Petkoski, S.; Caspers, S.; Jirsa, V.
10.1101/2022.02.17.480902 — neuroscience — Posted on 2022-05-30
216 Estimating axial diffusivity in the NODDI model
Howard, A. F.; Cottaar, M.; Drakesmith, M.; Fan, Q.; Huang, S. Y.; Jones, D. K.; Lange, F. J.; Mollink, J.; Rudrapatna, S. U.; Tian, Q.; Miller, K. L.; Jbabdi, S.
10.1101/2020.10.09.332700 — neuroscience — Posted on 2022-05-30
218 The neural code behind face recognition abilities
Faghel-Soubeyrand, S.; Ramon, M.; Bamps, E.; Zoia, M.; Woodhams, J.; Richoz, A.-R.; Caldara, R.; Gosselin, F.; Charest, I.
10.1101/2022.03.19.484245 — neuroscience — Posted on 2022-05-30
220 Short tandem repeats bind transcription factors to tune eukaryotic gene expression
Horton, C. A.; Alexandari, A. M.; Hayes, M. G. B.; Marklund, E.; Schaepe, J. M.; Aditham, A. K.; Shah, N.; Shrikumar, A. A.; Afek, A.; Greenleaf, W. J.; Gordan, R.; Zeitlinger, J.; Kundaje, A.; Fordyce, P. M.
10.1101/2022.05.24.493321 — biophysics — Posted on 2022-05-30
221 The termination of UHRF1-dependent PAF15 ubiquitin signaling is regulated by USP7 and ATAD5
Nakanishi, M.; Miyashita, R.; Nishiyama, A.; Chiba, Y.; Kori, S.; Kato, N.; Konishi, C.; Kumamoto, S.; Kozuka-Hata, H.; Oyama, M.; Kawasoe, Y.; Tsurimoto, T.; Takahashi, T.; Arita, K.
10.1101/2022.05.30.494002 — molecular biology — Posted on 2022-05-30
223 Direct activation of an innate immune system in bacteria by a viral capsid protein
Zhang, T.; Tamman, H.; Coppieters't Wallant, K.; Kurata, T.; LeRoux, M.; Srikant, S.; Brodiazhenko, T.; Cepauskas, A.; Talavera, A.; Martens, C.; Atkinson, G. C.; Hauryliuk, V.; Garcia-Pino, A.; Laub, M. T.
10.1101/2022.05.30.493996 — microbiology — Posted on 2022-05-30
225 The Arabidopsis ATP-Binding Cassette E protein ABCE2 is a conserved component of the translation machinery
Navarro-Quiles, C.; Mateo-Bonmati, E.; Candela, H.; Robles, P.; Martinez-Laborda, A.; Fernandez, Y.; Simura, J.; Ljung, K.; Rubio, V.; Ponce, M. R.; Micol, J. L.
10.1101/2022.05.30.493987 — plant biology — Posted on 2022-05-30
234 Respiratory mucosal vaccination of peptide-poloxamine-DNA nanoparticles provides complete protection against lethal SARS-CoV-2 challenge
Sun, S.; Li, E.; Zhao, G.; Tang, J.; Zuo, Q.; Cai, L.; Xu, C.; Sui, C.; Ou, Y.; Liu, C.; Li, H.; Ding, Y.; Li, C.; Lu, D.; Zhang, W.; Luo, P.; Cheng, P.; Gao, Y.; Tu, C.; Pitard, B.; Rosenecker, J.; Wang, B.; Liu, Y.; Zou, Q.; Guan, S.
10.1101/2022.05.29.493866 — immunology — Posted on 2022-05-30
236 Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro
Yadav, R.; Courouble, V. V.; Dey, S. K.; Harrison, J. J. E. K.; Timm, J.; Hopkins, J. B.; Slack, R. L.; Sarafianos, S. G.; Ruiz, F. X.; Griffin, P. R.; Arnold, E.
10.1101/2022.05.27.493767 — biochemistry — Posted on 2022-05-30
238 Multi-synaptic boutons are a feature of CA1 hippocampal connections that may underlie network synchrony
Rigby, M.; Grillo, F.; Compans, B.; Neves, G.; Gallinaro, J.; Nashashibi, S.; Vizcay-Barrena, G.; Levet, F.; Sibarita, J.-B.; Kirkland, A.; Fleck, R. A.; Clopath, C.; Burrone, J.
10.1101/2022.05.30.493836 — neuroscience — Posted on 2022-05-30
239 Designer Scaffolds for Interfacial Bioengineering
Hickey, R. J.; Leblanc Latour, M.; Harden, J. L.; Pelling, A.
10.1101/2020.11.06.371278 — biophysics — Posted on 2022-05-30
242 Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function and thrombosis.
Trory, J. S.; Munkacsi, A.; Sledz, K.; Goudswaard, L. J.; Heesom, K. J.; Moore, S. F.; Nabet, B.; Aggarwal, V. K.; Hers, I.
10.1101/2022.05.30.493973 — cell biology — Posted on 2022-05-30
243 Inferring light responses of primate retinal ganglion cells using intrinsic electrical signatures
Zaidi, M.; Aggarwal, G.; Shah, N. P.; Karniol-Tambour, O.; Goetz, G.; Madugula, S. S.; Gogliettino, A. R.; Wu, E. G.; Kling, A.; Brackbill, N.; Sher, A.; Litke, A. M.; Chichilnisky, E. J.
10.1101/2022.05.29.493858 — neuroscience — Posted on 2022-05-30
244 Pattern of frustration formation in the functional brain network
Saberi, M.; Khosrowabadi, R.; Khatibi, A.; Misic, B.; Jafari, G.
10.1101/2022.05.29.493932 — neuroscience — Posted on 2022-05-30
245 Signal Transformations and New Timing Rules of Hippocampal CA3 to CA1 Synapses
Gattas, S.; Le, A.; Abadchi, J. K.; Pruess, B.; Shen, Y.; Swindlehurst, A. L.; Yassa, M. A.; Lynch, G.
10.1101/2022.05.26.493588 — neuroscience — Posted on 2022-05-30
247 The impact of negative data sampling on antimicrobial peptide prediction
Sidorczuk, K.; Gagat, P.; Pietluch, F.; Kala, J.; Rafacz, D.; Bakala, L.; Slowik, J.; Kolenda, R.; Roediger, S.; Fingerhut, L. C.; Cooke, I.; Mackiewicz, P.; Burdukiewicz, M.
10.1101/2022.05.30.493946 — bioinformatics — Posted on 2022-05-30
248 Suction feeding of West African lungfish (Protopterus annectens): An XROMM analysis of jaw mechanics, cranial kinesis, and hyoid mobility.
Gartner, S. M.; Whitlow, K. R.; Laurence-Chasen, J. D.; Kaczmarek, E. B.; Granatosky, M. C.; Ross, C. F.; Westneat, M. W.
10.1101/2022.05.30.493759 — evolutionary biology — Posted on 2022-05-30
249 A genomic assessment of the marine-speciation paradox within the toothed whale superfamily Delphinoidea
Westbury, M. V.; Cabrera, A. A.; Rey-Iglesia, A.; De Cahsan, B.; Duchene, D. A.; Hartmann, S.; Lorenzen, E. D.
10.1101/2020.10.23.352286 — evolutionary biology — Posted on 2022-05-30
250 Egg-laying by female Aedes aegypti shapes the bacterial communities of breeding sites
Mosquera Duran, K. D.; Martinez Villegas, L. E.; da Rocha Fernandes, G.; Rocha David, M.; Maciel-de-Freitas, R.; Moreira, L. A.; Lorenzo, M. G.
10.1101/2022.02.22.481482 — ecology — Posted on 2022-05-30
251 Spatiotemporal heterogeneity and the long-term impact of meteorological , environmental and socio-economic factors of scrub typhus in China from 2012 to 2018
Qian, J.; Zhu, C.; Lv, H.; Chu, H.; He, J.; Wang, C.; Qi, Y.; Luo, Y.; Yue, N.; Wu, Y.; Ye, F.; Yi, J.; Wang, C.; Tan, W.-l.
10.1101/2022.05.30.493950 — ecology — Posted on 2022-05-30
252 Cyclic uniaxial mechanical load enhances chondrogenesis through entraining the molecular circadian clock
Vago, J.; Katona, E.; Takacs, R. A.; Docs, K.; Hajdu, T.; Kovacs, P.; Zakany, R.; van der Veen, D.; Matta, C.
10.1101/2021.10.26.465847 — cell biology — Posted on 2022-05-30
253 A human adenovirus encoding IFN-γ can transduce Tasmanian devil facial tumour cells and upregulate MHC-I
Kayigwe, A. N.; Darby, J. M.; Lyons, A. B.; Patchett, A. L.; Lisowski, L.; Liu, G.-S.; Flies, A. S.
10.1101/2022.05.29.493930 — immunology — Posted on 2022-05-30
259 Chemical genetic screening identifies nalacin as an inhibitor of GH3 amido synthetase for auxin conjugation
Jiang, K.; Xie, Y.; Zhu, Y.; Wang, N.; Luo, M.; Oda, T.; Guo, R.; Yu, Z.; Aizezi, Y.; Zhang, L.; Yan, Y.; Zhang, Y.; Bao, H.; Wang, Y.; Zhu, Z.; Huang, A.; Zhao, Y.; Asami, T.; Huang, H.; Guo, H.
10.1101/2022.05.29.493926 — plant biology — Posted on 2022-05-30
261 HSPB5 disease-associated mutations have long-range effects on structure and dynamics through networks of quasi-ordered interactions
Woods, C. N.; Ulmer, L. D.; Janowska, M. K.; Stone, N. L.; James, E. I.; Guttman, M.; Bush, M. F.; Klevit, R. E.
10.1101/2022.05.30.493970 — biophysics — Posted on 2022-05-30
262 Topological defects govern mesenchymal condensations, offering a morphology-based tool to predict cartilage differentiation
Makhija, E.; Zheng, Y.; Wang, J.; Leong, H. R.; Othman, R. B.; Ng, E. X.; Lee, E. H.; Tucker-Kellogg, L.; Lee, Y. H.; Yu, H.; Poon, Z.; Van Vliet, K. J.
10.1101/2022.05.30.493944 — biophysics — Posted on 2022-05-30
269 Correlations across timing cues in natural vocalizations predict judging synthetic sound burst durations.
Jane, M. B.; Pisupati, S.; Smith, K. E.; Tonelli, L. C.; Melo-Thomas, L.; Schwarting, R. K.; Wöhr, M.; Chrobak, J. J.; Read, H. L.
10.1101/2022.05.29.493898 — animal behavior and cognition — Posted on 2022-05-30
270 Cost-efficient whole genome-sequencing using novel mostly natural sequencing-by-synthesis chemistry and open fluidics platform
Almogy, G.; Pratt, M.; Oberstrass, F.; Lee, L.; Mazur, D.; Beckett, N.; Barad, O.; Soifer, I.; Perelman, E.; Etzioni, Y.; Sosa, M.; Jung, A.; Clark, T.; Lithwick-Yanai, G.; Pollock, S.; Hornung, G.; Levy, M.; Coole, M.; Howd, T.; Shand, M.; Farjoun, Y.; Emery, J.; Hall, G.; Lee, S. K.; Sato, T.; Magner, R.; Low, S.; Bernier, A.; Gandi, B.; Stohlman, J.; Nolet, C.; Donovan, S.; Blumenstiel, B.; Cipicchio, M.; Dodge, S.; Banks, E.; Lennon, N.; Gabriel, S.; Lipson, D.
10.1101/2022.05.29.493900 — genomics — Posted on 2022-05-30
271 Uncovering Hidden Enhancers Through Unbiased In Vivo Testing
Mannion, B. J.; Osterwalder, M.; Tran, S.; Plajzer-Frick, I.; Novak, C. S.; Afzal, V.; Akiyama, J. A.; Barton, S.; Beckman, E.; Garvin, T. H.; Godfrey, P.; Godoy, J.; Hunter, R. D.; Kato, M.; Kosicki, M.; Kronshage, A. H.; Lee, E. A.; Meky, E. M.; Pham, Q. T.; von Maydell, K.; Zhu, Y.; Lopez-Rios, J.; Dickel, D. E.; Visel, A.; Pennacchio, L. A.
10.1101/2022.05.29.493901 — genomics — Posted on 2022-05-30
274 M-Risk: A framework for assessing global fisheries management efficacy of sharks, rays, and chimaeras
Sherman, C. S.; Sant, G.; Simpfendorfer, C. A.; Digel, E. D.; Zubick, P.; Johnson, G.; Usher, M.; Dulvy, N. K.
10.1101/2022.05.29.493344 — ecology — Posted on 2022-05-30
275 LOMAR: LOcalization Microscopy Analysis in R
Theiss, M.; Brazma, A.; Uhlmann, V.; Heriche, J.-K.
10.1101/2022.05.30.493957 — cell biology — Posted on 2022-05-30
278 The effect of paracrine factors released by irradiated peripheral blood mononuclear cells on neutrophil extracellular trap formation
Klas, K.; Ondracek, A. S.; Hofbauer, T. M.; Mangold, A.; Pfisterer, K.; Laggner, M.; Copic, D.; Direder, M.; Bormann, D.; Ankersmit, H. J.; Mildner, M.
10.1101/2022.05.30.493953 — immunology — Posted on 2022-05-30
280 Defining specific cell states of MPTP-induced Parkinson's disease by single-nucleus RNA sequencing
Yunxia, G.; Junjie, M.; Hao, H.; Jitao, X.; Kaiqiang, Y.; Ning, C.; Qinyu, G.; Guangzhong, W.; Xiangwei, Z.
10.1101/2022.05.29.493938 — neuroscience — Posted on 2022-05-30
282 Early microglial response, myelin deterioration and lethality in mice deficient for very long chain ceramide synthesis in oligodendrocytes
Teo, J. D.; Mariam, O. C.; Spiteri, A. G.; Nicholson, M.; Song, H.; Khor, J. X.; McEwen, H. P.; Piccio, L.; Fletcher, J.; King, N. J. C.; Murray, S. S.; Brüning, J. C.; Don, A. S.
10.1101/2022.05.29.493337 — neuroscience — Posted on 2022-05-30
287 Atomic-Resolution Prediction of Degrader-mediated Ternary Complex Structures by Combining Molecular Simulations with Hydrogen Deuterium Exchange
Dixon, T.; MacPherson, D.; Mostofian, B.; Dauzhenka, T.; Lotz, S.; McGee, D.; Shechter, S.; Shrestha, U.; Wiewiora, R.; McDargh, Z. A.; Pei, F.; Pal, R.; Ribeiro, J. V.; Wilkerson, T.; Sachdeva, V.; Gao, N.; Jain, S.; Sparks, S.; Li, Y.; Vinitsky, A.; Razavi, A. M.; Kolossvary, I.; Imbriglio, J.; Evdokimov, A.; Bergeron, L.; Zhou, W.; Adhikari, J.; Ruprecht, B.; Dickson, A.; Xu, H.; Sherman, W.; Izaguirre, J. A.
10.1101/2021.09.26.461830 — biophysics — Posted on 2022-05-30
289 Invigorating human MSCs for transplantation therapy via Nrf2/DKK1 co- stimulation in a mice acute-on-chronic liver failure model
Chen, F.; Che, Z.; Liu, Y.; Luo, P.; Xiao, L.; Song, Y.; Wang, C.; Dong, Z.; Li, M.; Tipoe, G. L.; Wu, D.; Yang, M.; Lv, Y.; Wang, F.; Wang, H.; Xiao, J.
10.1101/2022.05.29.493908 — molecular biology — Posted on 2022-05-30
290 Genomic surveillance of carbapenem-resistant Klebsiella in Wales reveals persistent spread of K. pneumoniae ST307 and adaptive evolution of pOXA-48-like plasmids
David, S.; Mentasti, M.; Sands, K.; Portal, E.; Graham, L.; Watkins, J.; Williams, C.; Healy, B.; Spiller, O. B.; Aanensen, D.; Wootton, M. B.; Jones, L. S.
10.1101/2022.05.25.492139 — microbiology — Posted on 2022-05-30
293 Sexual coercion in a natural mandrill population
Smit, N.; Baniel, A.; Roura-Torres, B.; Amblard-Rambert, P.; Charpentier, M. J. E.; Huchard, E.
10.1101/2022.02.07.479393 — ecology — Posted on 2022-05-30
301 Mechanical loading of cranial joints minimizes the craniofacial phenotype in Crouzon syndrome
Moazen, M.; Hejazi, M.; Savery, D.; Jones, D.; Marghoub, A.; Alazmani, A.; Pauws, E.
10.1101/2021.08.31.458360 — biophysics — Posted on 2022-05-30
307 Structural insight into the individual variability architecture of the functional brain connectome
Sun, L.; Liang, X.; Duan, D.; Liu, J.; Chen, Y.; Wang, X.; Liao, X.; Xia, M.; Zhao, T.; He, Y.
10.1101/2022.02.16.480803 — neuroscience — Posted on 2022-05-29
308 Cytoplasmic HIF-2α correlates to proliferation and predicts worse outcome in sympathetic paraganglioma
Karakaya, S.; Gunnesson, L.; Elias, E.; Martos Salvo, P.; Robledo, M.; Nilsson, O.; Wängberg, B.; Abel, F.; Pahlman, S.; Muth, A.; Mohlin, S.
10.1101/2022.05.27.493680 — cancer biology — Posted on 2022-05-29
310 Vitamin C triggers NF-κB-driven epigenetic reprogramming and enhanced immunogenic responses in dendritic cells
Morante-Palacios, O.; Godoy-Tena, G.; Calafell-Segura, J.; Ciudad, L.; Martinez-Caceres, E.; Sardina, J. L.; Ballestar, E.
10.1101/2022.05.26.493381 — immunology — Posted on 2022-05-29
316 Disruption of place cell remapping by scopolamine during aversive learning
Blair, G. J.; Guo, C.; Fanselow, M.; Golshani, P.; Aharoni, D.; Blair, H. T.
10.1101/2022.05.26.493592 — neuroscience — Posted on 2022-05-29
317 Gcm: a novel anti-inflammatory transcriptional cascade conserved from flies to humans
Pavlidaki, A.; Panic, R.; Monticelli, S.; Riet, C.; Yuasa, Y.; Cattenoz, P. B.; Nait-Oumesmar, B.; Giangrande, A.
10.1101/2022.05.29.493864 — neuroscience — Posted on 2022-05-29
319 Topography of mutational signatures in human cancer
Otlu-Saritas, B.; Diaz-Gay, M.; Vermes, I.; Bergstrom, E. N.; Barnes, M.; Alexandrov, L. B.
10.1101/2022.05.29.493921 — cancer biology — Posted on 2022-05-29
320 Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection
VanDyke, D.; Iglesias, M.; Tomala, J.; Young, A.; Smith, J.; Perry, J. A.; Gebara, E.; Cross, A. R.; Cheung, L. S.; Dykema, A. G.; Orcutt-Jahns, B. T.; Henclova, T.; Golias, J.; Balolong, J.; Tomasovic, L. M.; Funda, D.; Meyer, A. S.; Pardoll, D. M.; Hester, J.; Issa, F.; Hunter, C. A.; Anderson, M. S.; Bluestone, J. A.; Raimondi, G.; Spangler, J. B.
10.1101/2022.05.29.493918 — bioengineering — Posted on 2022-05-29
321 Ligand-induced shifts in conformational ensembles that predict transcriptional activation
Khan, S. H.; Braet, S. M.; Koehler, S. J.; Elacqua, E.; Anand, G. S.; Okafor, C. D.
10.1101/2022.05.29.493907 — biochemistry — Posted on 2022-05-29
323 Single cell RNA-seq by mostly-natural sequencing by synthesis
Simmons, S. K.; Lithwick-Yanai, G.; Adiconis, X.; Oberstrass, F.; Iremadze, N.; Geiger-Schuller, K.; Thakore, P. I.; Frangieh, C. J.; Barad, O.; Almogy, G.; Rozenblatt-Rosen, O.; Regev, A.; Lipson, D.; Levin, J. Z.
10.1101/2022.05.29.493705 — genomics — Posted on 2022-05-29
326 Delimiting the cryptic diversity and host preferences of Sycophila parasitoid wasps associated with oak galls using phylogenomic data
Zhang, Y. M.; Sheikh, S.; Ward, A. K. G.; Forbes, A. A.; Prior, K.; Stone, G. N.; Gates, M.; Egan, S.; Zhang, L. N.; Davis, C.; Weinersmith, K.; Melika, G.; Lucky, A.
10.1101/2022.01.21.477213 — evolutionary biology — Posted on 2022-05-29
328 Phenotypic stasis with genetic divergence
Mallard, F.; Noble, L.; Guzella, T.; Afonso, B.; Baer, C. F.; Teotonio, H.
10.1101/2022.05.28.493856 — evolutionary biology — Posted on 2022-05-29
332 Expansion microscopy reveals subdomains in C. elegans germ granules
Suen, K. M.; Sheard, T. M. D.; Lin, C.-C.; Milonaityte, D.; Jayasinghe, I.; Ladbury, J. E.
10.1101/2022.05.29.493872 — cell biology — Posted on 2022-05-29
334 Direct detection of RNA repair by nanopore sequencing
White, L. K.; Strugar, S. M.; MacFadden, A.; Hesselberth, J. R.
10.1101/2022.05.29.493267 — molecular biology — Posted on 2022-05-29
337 Ablation of SYK kinase from primary human Natural Killer cells via CRISPR/Cas9 enhances cytotoxicity and cytokine production
Dahlvang, J. D.; Dick, J. K.; Sangala, J. A.; Pomeroy, E. J.; Snyder, K. M.; Moushon, J. M.; Thefaine, C. E.; Wu, J.; Hamilton, S. E.; Felices, M.; Miller, J. S.; Walcheck, B.; Webber, B. R.; Moriarity, B. S.; Hart, G. T.
10.1101/2022.05.29.493889 — immunology — Posted on 2022-05-29
338 A dual role for CRTH2 in acute lung injury
Jung, E.; Cohen, A. J.; Howell, R.; Cosme, C.; Tsang, D.; Ristic, N.; Dela Cruz, C. S.; Spiegel, D.; Chupp, G. L.; Gautam, S.
10.1101/2022.05.29.493897 — immunology — Posted on 2022-05-29
339 Iron regulates contrasting toxicity of uropathogenic Eschericia coli in macrophages and epithelial cells.
Dabral, D.; Ghosh, H.; Niwa, M.; Hirayama, T.; Boer, R. d.; Vos, M. d.; van den Bogaart, G.
10.1101/2022.05.29.493834 — immunology — Posted on 2022-05-29
346 2-hydroxyglutarate controls centromere and heterochromatin conformation and function in the male germline
Mayorek, N.; Schlossberg, M.; Mansour, Y.; Pillar, N.; Stein, I.; Mushasha, F.; Baziza, G.; Medvedev, E.; Manevitch, Z.; Menzel, J.; Aizenshtein, E.; Sarvin, B.; Sarvin, N.; Shlomi, T.; Klutstein, M.; Pikarsky, E.
10.1101/2022.05.29.493890 — cell biology — Posted on 2022-05-29
356 Syntaxin1 Ser14 Phosphorylation is Required for Non-Vesicular Dopamine Release
Shekar, A.; Mabry, S. J.; Cheng, M. H.; Aguilar, J. I.; Patel, S.; Zanella, D.; Saleeby, D. P.; Zhu, Y.; Romanazzi, T.; Ulery-Reynolds, P.; Bahar, I.; Carter, A. M.; Matthies, H. J. G.; Galli, A.
10.1101/2022.05.27.493791 — neuroscience — Posted on 2022-05-29
357 N-Terminomic Changes of Neurons During Excitotoxicity Reveal Proteolytic Events Associated with Synaptic Dysfunctions and Inform Potential Targets for Neuroprotection
Ameen, S. S.; Griem-Krey, N.; Dufour, A.; Hossain, M. I.; Hoque, A.; Sturgeon, S.; Nandurkar, H.; Draxler, D. F.; Medcalf, R. L.; Kamaruddin, M. A.; Lucet, I. S.; Leeming, M. G.; Liu, D.; Dhillon, A.; Lim, J. P.; Basheer, F.; Zhu, H.-J.; Bokhari, L.; Roulston, C.; Paradkar, P. N.; Kleifeld, O.; Clarkson, A. N.; Wellendorph, P.; Ciccotosto, G. D.; Williamson, N. A.; Ang, C.-S.; Cheng, H.-C.
10.1101/2022.03.13.484119 — neuroscience — Posted on 2022-05-29
358 An autoactive NB-LRR gene causes Rht13 dwarfism in wheat
Borrill, P.; Mago, R.; Xu, T.; Ford, B.; Williams, S. J.; Derkx, A.; Bovill, W. D.; Hyles, J.; Bhatt, D.; Xia, X.; MacMillan, C.; White, R.; Buss, W.; Molnar, I.; Walkowiak, S.; Olsen, O.-A.; Dolezel, J.; Pozniak, C. J.; Spielmeyer, W.
10.1101/2022.05.28.493833 — plant biology — Posted on 2022-05-29
359 Skeletal muscle Nox4 knockout prevents and Nox2 knockout blunts loss of maximal diaphragm force in mice with heart failure with reduced ejection fraction
Kumar, R. A.; Hahn, D.; Kelley, R. C.; Muscato, D. R.; Shamoun, A.; Curbelo-Bermudez, N.; Butler, W. G.; Yegorova, S.; Ryan, T. E.; Ferreira, L.
10.1101/2022.05.27.493689 — physiology — Posted on 2022-05-29
361 Hippocampal Concentrations Drive Seizures in a Rat Model for Cefepime-induced Neurotoxicity
Lesnicki, E.; Pais, G.; Marianski, S.; Valdez, K.; Gibson, Z.; Christopher, J.; Scheetz, M. H.
10.1101/2022.05.26.493582 — pharmacology and toxicology — Posted on 2022-05-29
362 On predicting heterogeneity in nanoparticle dosage
Dowling, C. V.; Cevaal, P. M.; Faria, M.; Johnston, S. T.
10.1101/2022.05.26.493665 — biophysics — Posted on 2022-05-29
364 ICAT: A Novel Algorithm to Robustly Identify Cell States Following Perturbations in Single Cell Transcriptomes
Hawkins, D. Y.; Zuch, D. T.; Huth, J.; Rodriguez-Sastre, N. C.; McCutcheon, K. R.; Glick, A.; Lion, A. T.; Johnson, W. E.; Bradham, C.
10.1101/2022.05.26.493603 — bioinformatics — Posted on 2022-05-29
370 Lighting Up Mechanosensation: dyeing to see PIEZO2
Villarino, N. W.; Dubin, A. E.; Patapoutian, A.; Marshall, K. L.
10.1101/2022.05.26.493600 — neuroscience — Posted on 2022-05-29
372 Functional imaging and quantification of multi-neuronal olfactory responses in C. elegans
Lin, A.; Qin, S.; Casademunt, H.; Wu, M.; Hung, W.; Cain, G.; Tan, N.; Valenzuela, R.; Lesanpezeshki, L.; Pehlevan, C.; Venkatachalam, V.; Zhen, M.; Samuel, A.
10.1101/2022.05.27.493772 — neuroscience — Posted on 2022-05-29
375 Female reproductive dormancy in Drosophila melanogaster is regulated by DH31-producing neurons projecting into the corpus allatum
Kurogi, Y.; Imura, E.; Mizuno, Y.; Hoshino, R.; Nouzova, M.; Matsuyama, S.; Mizoguchi, A.; Kondo, S.; Tanimoto, H.; Noriega, F. G.; Niwa, R.
10.1101/2022.05.28.492955 — physiology — Posted on 2022-05-29
376 PRC2 Inactivating Mutations in Cancer are Synthetic Lethal with DNMT1 Targeted Therapy via Enhanced Viral Mimicry
Patel, A. J.; Warda, S.; Maag, J. L. V.; Misra, R.; Miranda-Roman, M. A.; Pachai, M. R.; Lee, C. J.; Li, D.; Wang, N.; Bayshtok, G.; Meng, Y.; Wong, E. W. P.; Yan, J.; Giff, E.; Pappalardi, M. B.; McCabe, M. T.; Fletcher, J. A.; Scandura, J. M.; Koche, R. P.; Glass, J. L.; Antonescu, C. R.; Zheng, D.; Chen, Y.; Chi, P.
10.1101/2022.05.28.493429 — cancer biology — Posted on 2022-05-29
378 Prioritizing virtual screening with interpretable interaction fingerprints
Fassio, A. V.; Shub, L.; Ponzoni, L.; McKinley, J.; O'Meara, M. J.; Ferreira, R. S.; Keiser, M. J.; de Melo Minardi, R. C.
10.1101/2022.05.25.493419 — bioinformatics — Posted on 2022-05-29
383 Trade-offs in telemetry tag programming for deep-diving cetaceans: data longevity, resolution, and continuity
Cioffi, W. R.; Quick, N. J.; Swaim, Z. T.; Foley, H. J.; Waples, D. M.; Webster, D. L.; Baird, R. W.; Southall, B. L.; Nowacek, D. P.; Read, A. J.
10.1101/2022.05.28.493822 — animal behavior and cognition — Posted on 2022-05-29
387 Genetic architectures of postmating isolation and morphology of two highly diverged rockfishes (genus Sebastes)
Muto, N.; Kawasaki, T.; Kakioka, R.; Nagano, A. J.; Shimizu, Y.; Inose, S.; Shimizu, Y.; Takahashi, H.
10.1101/2022.05.27.493803 — evolutionary biology — Posted on 2022-05-29
388 Precipitation is the main axis of tropical phylogenetic turnover across space and time
Ringelberg, J. J.; Koenen, E. J. M.; Sauter, B.; Aebli, A.; Rando, J. G.; Iganci, J. R.; de Queiroz, L. P.; Murphy, D. J.; Gaudeul, M.; Bruneau, A.; Luckow, M.; Lewis, G. P.; Miller, J. T.; Simon, M. F.; Jordao, L. S. B.; Morales, M.; Bailey, C. D.; Nageswara-Rao, M.; Loiseau, O.; Pennington, R. T.; Dexter, K. G.; Zimmermann, N. E.; Hughes, C. E.
10.1101/2022.05.27.493777 — evolutionary biology — Posted on 2022-05-29
389 Determination of a target image of freshwater fishes composition in a mitigation project using eDNA metabarcoding methods
Ito, G.; Yamauchi, H.; Shigeyoshi, M.; Ashino, K.; Yonashiro, C.; Asami, M.; Goto, Y.; Yamanaka, H.
10.1101/2022.05.26.493668 — ecology — Posted on 2022-05-29
391 Autophagy controls mucus secretion from intestinal goblet cells by alleviating ER stress
Naama, M.; Telpaz, S.; Awad, A.; Ben-Simon, S.; Harshuk-Shabso, S.; Modilevsky, S.; Rubin, E.; Sawaed, J.; Zelik, L.; Zigdon, M.; Asulin, N.; Turjeman, S.; Werbner, M.; Wongkuna, S.; Schroeder, B.; Nyska, A.; Nuriel-Ohayon, M.; Bel, S.
10.1101/2022.05.26.493604 — immunology — Posted on 2022-05-29
392 Peritoneal autoantibody landscape in endometriosis
Harden, S. L.; Tan, T. Y.; Ku, C. W.; Zhou, J.; Chen, Q.; Chan, J. K. Y.; Brosens, J.; Lee, Y. H.
10.1101/2022.05.27.493373 — immunology — Posted on 2022-05-29
394 Secretin modulates appetite via brown adipose tissue - brain axis
Sun, L.; Laurila, S.; Lahesmaa, M.; Rebelos, E.; Virtanen, K. A.; Schnabl, K.; Klingenspor, M.; Nummenmaa, L.; Nuutila, P.
10.1101/2022.05.26.493657 — neuroscience — Posted on 2022-05-29
398 Signal Transformations and New Timing Rules of Hippocampal CA3 to CA1 Synapses
Gattas, S.; Le, A.; Abadchi, J. K.; Pruess, B.; Shen, Y.; Swindlehurst, A. L.; Yassa, M. A.; Lynch, G.
10.1101/2022.05.26.493588 — neuroscience — Posted on 2022-05-29
401 A Diabetic Mice Model For Studying Skin Wound Healing
Poblete Jara, C.; Nogueira, G.; Morari, J.; Paulino do Prado, T.; Medeiros Bezerra, R.; Bombassaro, B.; Velloso, L. A.; Velander, W.; de Araujo, E. P.
10.1101/2022.05.28.493835 — physiology — Posted on 2022-05-29
403 IDPConformerGenerator: A Flexible Software Suite for Sampling Conformational Space of Disordered Protein States
Teixeira, J. M. C.; Liu, Z. H.; Namini, A.; Li, J.; Vernon, R. M.; Krzeminski, M.; Shamandy, A. A.; Zhang, O.; Haghighatlari, M.; Yu, L.; Head-Gordon, T.; Forman-Kay, J. D.
10.1101/2022.05.28.493726 — biophysics — Posted on 2022-05-29
414 Background modeling, Quality Control and Normalization for GeoMx RNA data with GeoDiff
Yang, L.; Yang, Z.; Danaher, P.; Zimmerman, S.; Hether, T.; Henderson, D. A.; Beechem, J. M.
10.1101/2022.05.26.493637 — bioinformatics — Posted on 2022-05-29
415 SBML to bond graphs: from conversion to composition
Shahidi, N.; Pan, M.; Tran, K.; Crampin, E.; Nickerson, D. P.
10.1101/2022.05.25.493355 — bioengineering — Posted on 2022-05-29
419 Affinity-optimizing variants within cardiac enhancers disrupt heart development and contribute to cardiac traits
Jindal, G. A.; Bantle, A. T.; Solvason, J. J.; Grudzien, J. L.; D'Antonio-Chronowska, A.; Lim, F.; Le, S. H.; Larsen, R. O.; Klie, A.; Frazer, K. A.; Farley, E. K.
10.1101/2022.05.27.493636 — genomics — Posted on 2022-05-29
420 Genomic analyses of the Linum distyly supergene reveal convergent evolution at the molecular level
Gutierrez-Valencia, J.; Fracassetti, M.; Berdan, E. L.; Bunikis, I.; Soler, L.; Dainat, J.; Kutschera, V. E.; Losvik, A.; Desamore, A.; Hughes, W.; Foroozani, A.; Laenen, B.; Pesquet, E.; Abdelaziz, M.; Vinnere Pettersson, O.; Nystedt, B.; Brennan, A.; Arroyo, J.; Slotte, T.
10.1101/2022.05.27.493681 — evolutionary biology — Posted on 2022-05-29
424 Adipocytes reprogram carbon and nitrogen metabolism to maintain lipogenic flux in the absence of Bckdha
Green, C. R.; Wessendorf-Rodriguez, K. A.; Turner, R.; Hover, J. D.; Murphy, A. N.; Wallace, M.; Metallo, C. M.
10.1101/2022.05.27.493780 — cell biology — Posted on 2022-05-29
425 Oocytes maintain ROS-free mitochondrial metabolism by suppressing complex I
Rodriguez-Nuevo, A.; Torres-Sanchez, A.; Duran, J.; De Guirior, C.; Martinez-Zamora, M. A.; Boke, E.
10.1101/2022.05.27.493392 — cell biology — Posted on 2022-05-29
428 Peripheral ghrelin administration prevents the behavioral effects of restraint stress in mice: possible implication of PVNCRH neurons.
dos-Santos, R. C.; Flores, R. A.; Jesus, A. A.; Rorato, R.; Mecawi, A. S.; Antunes-Rodrigues, J.; Elias, L. L. K.
10.1101/2022.05.26.493640 — neuroscience — Posted on 2022-05-29
432 Disruption of place cell remapping by scopolamine during aversive learning
Blair, G. J.; Guo, C.; Fanselow, M.; Golshani, P.; Aharoni, D.; Blair, H. T.
10.1101/2022.05.26.493592 — neuroscience — Posted on 2022-05-29
438 Impaired hepatic autophagy exacerbates xenobiotics induced liver injury
Byrnes, K.; Bailey, N. T.; Mercer, A.; Joshi, S.; Liu, G.; Yin, X.-M.; Khambu, B.
10.1101/2022.05.27.493749 — pharmacology and toxicology — Posted on 2022-05-29
444 Stable High-Concentration Monoclonal Antibody Formulations Enabled by an Amphiphilic Copolymer Excipient
Klich, J. H.; Kasse, C. M.; Mann, J. L.; Huang, Y.; d'Aquino, A. I.; Grosskopf, A. K.; Baillet, J.; Fuller, G. G.; Appel, E.
10.1101/2022.05.25.493499 — bioengineering — Posted on 2022-05-28
445 Nanoneedles for targeted siRNA silencing of p16 in the Human Corneal Endothelium
Maurizi, E.; Martella, D. A.; Schiroli, D.; Merra, A.; Mustfa, S. A.; Pellegrini, G.; Macaluso, C.; Chiappini, C.
10.1101/2022.05.27.493597 — bioengineering — Posted on 2022-05-29
447 coiaf: directly estimating complexity of infection with allele frequencies
Paschalidis, A.; Watson, O. J.; Aydemir, O.; Verity, R.; Bailey, J. A.
10.1101/2022.05.26.493561 — genomics — Posted on 2022-05-28
453 Genomic and environmental factors shape gill microbiome activity in an Amazonian teleost holobiont
Sylvain, F.-E.; Leroux, N.; Normandeau, E.; Holland, A.; Bouslama, S.; Mercier, P.-L.; Luis Val, A.; Derome, N.
10.1101/2022.05.27.493806 — ecology — Posted on 2022-05-29
455 Orchestration of alternative splicing regulates bone marrow mesenchymal stem cells fate during aging
Xiao, Y.; Cai, G.-P.; Feng, X.; Guo, Q.; Huang, Y.; Su, T.; Li, C.-J.; Luo, X.-H.; Zheng, Y.-J.; Yang, M.
10.1101/2022.05.27.493685 — cell biology — Posted on 2022-05-29
463 High frequency DBS-like optogenetic stimulation of nucleus accumbens dopamine D2 receptor-containing neurons attenuates cocaine reinstatement in male rats
Swinford-Jackson, S. E.; Huffman, P. J.; Knouse, M. C.; Thomas, A. S.; Mankame, S.; Worobey, S. J.; Sarmiento, M.; Coleman, A.; Pierce, R. C.
10.1101/2022.05.26.493617 — neuroscience — Posted on 2022-05-28
465 The right inferior frontal gyrus as pivotal node and effective regulator of the basal ganglia-thalamocortical response inhibition circuit in humans
Zhuang, Q.; Qiao, L.; Xu, L.; Yao, S.; Chen, S.; Zheng, X.; Li, J.; Fu, M.; Li, K.; Vatansever, D.; Ferraro, S.; Kendrick, K. M.; Becker, B.
10.1101/2022.05.26.493546 — neuroscience — Posted on 2022-05-28
466 Development and validation of an expanded antibody toolset that captures alpha-synuclein pathological diversity in Lewy body diseases
Altay, M. F.; Kumar, S. T.; Burtscher, J.; Jagannath, S.; Strand, C.; Miki, Y.; Parkkinen, L.; Holton, J. L.; Lashuel, H. A.
10.1101/2022.05.26.493598 — neuroscience — Posted on 2022-05-28
469 Leucine-Rich Repeat Kinase 2 limits dopamine D1 receptor signaling in the striatum and biases against heavy persistent alcohol drinking
da Silva e Silva, D.; Matsui, A.; Murray, E. M.; Mamais, A.; Shaw, M.; Ron, D.; Cookson, M. R.; Alvarez, V. A.
10.1101/2022.05.26.493614 — neuroscience — Posted on 2022-05-29
471 yEvo: a modular eukaryotic genetics and evolution research experience for high school students
Taylor, B.; Warwick, A. R.; Skophammer, R.; Boyer, J. M.; Geck, R. C.; Gunkelman, K.; Walson, M.; Rowley, P. A.; Dunham, M. J.
10.1101/2022.05.26.493490 — scientific communication and education — Posted on 2022-05-28
473 An Automated Pipeline for Differential Cell Counts on Whole-Slide Bone Marrow Aspirate Smears
Lewis, J. E.; Shebelut, C. W.; Drumheller, B. R.; Zhang, X.; Shanmugam, N.; Attieh, M.; Horwath, M. C.; Khanna, A.; Smith, G. H.; Gutman, D. A.; Aljudi, A.; Cooper, L. A. D.; Jaye, D. L.
10.1101/2022.05.26.493480 — pathology — Posted on 2022-05-28
474 Androgen Receptor is a Determinant of Melanoma Targeted Drug Resistance
Samarkina, A.; Youssef, M. K.; Ostano, P.; Ghosh, S.; Ma, M.; Tassone, B.; Proust, T.; Chiorino, G.; Levesque, M. P.; Dotto, G.-P.
10.1101/2022.05.27.493720 — cancer biology — Posted on 2022-05-28
475 The histone H3.3 K27M mutation found in diffuse midline gliomas coordinately disrupts adjacent H3.3 Ser31 phosphorylation and the fidelity of chromosome segregation
Day, C. A.; Grigore, F.; Hakkim, F. L.; Langfald, A.; Fadness, S.; Schwab, P.; Sepaniac, L.; Stumpff, J.; Daniels, D. J.; Vaughan, K. T.; Robinson, J. P.; Hinchcliffe, E. H.
10.1101/2022.05.27.493485 — cancer biology — Posted on 2022-05-28
476 Evolutionary rescue is promoted in compact cellular populations
Aif, S.; Appold, N.; Kampman, L.; Hallatschek, O.; Kayser, J.
10.1101/2022.05.27.493727 — biophysics — Posted on 2022-05-28
477 MoBIE: A Fiji plugin for sharing and exploration of multi-modal cloud-hosted big image data
Pape, C.; Meechan, K.; Moreva, E.; Schorb, M.; Chiaruttini, N.; Zinchenko, V.; Vergara, H.; Mizzon, G.; Moore, J.; Arendt, D.; Kreshuk, A.; Schwab, Y.; Tischer, C.
10.1101/2022.05.27.493763 — bioinformatics — Posted on 2022-05-28
480 Cross-Modal Autoencoder Framework Learns Holistic Representations of Cardiovascular State
Radhakrishnan, A.; Friedman, S. F.; Khurshid, S.; Ng, K.; Batra, P.; Lubitz, S. A.; Philippakis, A. A.; Uhler, C.
10.1101/2022.05.26.493497 — bioinformatics — Posted on 2022-05-28
481 Accelerating single-cell genomic analysis with GPUs
Nolet, C.; Lal, A.; Ilango, R.; Dyer, T.; Movva, R.; Zedlewski, J.; Israeli, J.
10.1101/2022.05.26.493607 — bioinformatics — Posted on 2022-05-28
483 LoRTIS Software Suite: Transposon mutant analysis using long-read sequencing
Lott, M.; Yasir, M.; Turner, A. K.; bastkowski, s.; Page, A. J.; Webber, M. A.; Charles, I. G.
10.1101/2022.05.26.493556 — bioinformatics — Posted on 2022-05-28
489 A single-cell atlas of bobtail squid visual and nervous system highlights molecular principles of convergent evolution
Gavriouchkina, D.; Tan, Y.; Künzli-Ziadi, F.; Hasegawa, Y.; Piovani, L.; Zhang, L.; Sugimoto, C.; Luscombe, N.; Marletaz, F.; Rokhsar, D. S.
10.1101/2022.05.26.490366 — evolutionary biology — Posted on 2022-05-28
493 Mutual repression between JNK/AP-1 and JAK/STAT stratifies cell behaviors during tissue regeneration
Jaiswal, J.; Engesser, R.; Peyroton, A.; Weichselberger, V.; Crucianelli, C.; Grass, I.; Timmer, J.; Classen, A.-K.
10.1101/2022.05.11.491445 — developmental biology — Posted on 2022-05-28
494 REM Sleep Movements in Parkinson's Disease: Is the Basal Ganglia Engaged?
Verma, A. K.; Lenis, S. F. A.; Aman, J. E.; Sanabria, D. E.; Wang, J.; Pearson, A.; Hill, M.; Patriat, R.; Schrock, L. E.; Cooper, S. E.; Park, M. C.; Harel, N.; Howell, M. J.; MacKinnon, C. D.; Vitek, J. L.; Johnson, L. A.
10.1101/2022.05.25.493494 — neuroscience — Posted on 2022-05-28
496 Structural dynamics underlying gating and regulation in IP3R channel
Fan, G.; Baker, M. R.; Terry, L. E.; Arige, V.; Chen, M.; Seryshev, A.; Baker, M. L.; Ludtke, S. J.; Yule, D. I.; Serysheva, I. I.
10.1101/2022.05.27.493711 — biophysics — Posted on 2022-05-28
498 Dityrosine cross-links are present in Alzheimer's disease-derived tau oligomers and paired helical filaments (PHF) which promotes the stability of PHF-core tau (297-391) in vitro.
Maina, M.; Al-Hilaly, Y.; Oakley, S.; Burra, G.; Khanom, T.; Biasetti, L.; Mengham, K.; Marshall, K. E.; Harrington, C.; Wischik, C.; Serpell, L. C.
10.1101/2022.05.28.493839 — biochemistry — Posted on 2022-05-28
499 Recurrent loss of an immunity gene that protects Drosophila against a major natural parasite
Arunkumar, R.; Zhou, S. O.; Day, J. P.; Bakare, S.; Pitton, S.; Hsing, C.-Y.; O Boyle, S.; Pascual-Gil, J.; Clark, B.; Chandler, R. J.; Leitao, A. B.; Jiggins, F. M.
10.1101/2022.05.27.493757 — evolutionary biology — Posted on 2022-05-28
505 G protein-coupled receptor 151 regulates glucose metabolism and hepatic gluconeogenesis
Bielczyk-Maczynska, E.; Zhao, M.; Zushin, P.-J. H.; Schnurr, T. M.; Kim, H.-J.; Li, J.; Nallagatla, P.; Sangwung, P.; Park, C.; Cornn, C.; Stahl, A.; Svensson, K. J.; Knowles, J. W.
10.1101/2022.05.25.493489 — physiology — Posted on 2022-05-28
506 Doublecortin like kinase 1 is a target in squamous cell carcinoma
Standing, D.; Arnold, L.; Dandawate, P.; Ottemann, B.; Snyder, V.; Ponnurangam, S.; Subramaniam, D.; Srinivasan, P.; Choudhury, S.; New, J.; Kwatra, D.; Ramamoorthy, P.; Roy, B. C.; Shadoin, M.; Al-Rajabi, R.; O'Neil, M.; Gunewardena, S.; Ashcraft, J.; Umar, S.; Weir, S. J.; Tawfik, O.; Padhye, S.; Anant, S.; Thomas, S. M.
10.1101/2022.05.26.493670 — cancer biology — Posted on 2022-05-28
507 The BRD4S-LOXL2-MED1 interaction at the forefront of cell cycle transcriptional control in triple-negative breast cancer
Pascual-Reguant, L.; Tian, T. V.; Datta, D.; Cianferoni, D.; Kourtis, S.; Ganez Zapater, A.; Cannata, C.; Serra Camprubi, Q.; Espinar, L.; Guirola, M.; Querol, J.; Miro Canturri, A.; Arribas, J.; Serrano, L.; Peiro, S.; Sdelci, S.
10.1101/2022.05.27.493725 — cancer biology — Posted on 2022-05-28
508 Inferring gene expression models from snapshot RNA data
Moyer, C.; Kilic, Z.; Schweiger, M. C.; Shepherd, D. P.; Presse, S. P.
10.1101/2022.05.28.493734 — biophysics — Posted on 2022-05-28
509 Improved prediction of bacterial CRISPRi guide efficiency through data integration and automated machine learning
Yu, Y.; Gawlitt, S.; Barros de Andrade e Sousa, L.; Merdivan, E.; Piraud, M.; Beisel, C.; Barquist, L.
10.1101/2022.05.27.493707 — bioinformatics — Posted on 2022-05-28
510 Spinal Fusion Properties of Mechanically-Reinforced, Osteomodulatory Chitosan Hydrogels
Darkow, B. T.; Herbert, J. P.; Messler, M. J.; Grisolano, A.; Hemmerla, A. J.; Kimes, A. D.; Lanza, J.; Sun, Y.; Crim, J. R.; Stensby, D.; Wan, C.; Moore, D. K.; Ulery, B. D.
10.1101/2022.05.26.493540 — bioengineering — Posted on 2022-05-28
512 Multi-marker DNA metabarcoding detects suites of environmental gradients from an urban harbour
Robinson, C. V.; Porter, T. M.; McGee, K. M.; McCusker, M.; Wright, M. T. G.; Hajibabaei, M.
10.1101/2022.04.17.488590 — genomics — Posted on 2022-05-28
515 The dynseq genome browser track enables visualization of context-specific, dynamic DNA sequence features at single nucleotide resolution
Nair, S.; Barrett, A.; Li, D.; Raney, B. J.; Lee, B. T.; Kerpedjiev, P.; Ramalingam, V.; Pampari, A.; Lekschas, F.; Wang, T.; Haeussler, M.; Kundaje, A.
10.1101/2022.05.26.493621 — genomics — Posted on 2022-05-28
516 Systemic interindividual epigenetic variation in humans is associated with transposable elements and under strong genetic control
Gunasekara, C. J.; MacKay, H.; Scott, C. A.; Li, S.; Laritsky, E.; Baker, M. S.; Grimm, S. L.; Jun, G.; Li, Y.; Chen, R.; Wiemels, J. L.; Coarfa, C.; Waterland, R. A.
10.1101/2022.05.27.493722 — genetics — Posted on 2022-05-28
517 A proton pump enhancing photosynthesis links phagocytosis to marine phytoplankton symbiogenesis
Yee, D. P.; Samo, T. J.; Abbriano, R. M.; Shimasaki, B.; Vernet, M.; Mayali, X.; Weber, P. K.; Mitchell, B. G.; Hildebrand, M.; Tresguerres, M.
10.1101/2022.05.26.493626 — evolutionary biology — Posted on 2022-05-28
520 OxPhos Dysfunction Causes Hypermetabolism and Reduces Lifespan in Cells and in Patients with Mitochondrial Diseases
Sturm, G.; Karan, K. R.; Monzel, A.; Santhanham, B. S.; Taivassalo, T.; Bris, C.; Duplaga, S. A.; Cross, M.; Towheed, A.; Higgins-Chen, A.; McManus, M. J.; Cardenas, A.; Lin, J.; Epel, E. S.; Rahman, S.; Vissing, J.; Grassi, B.; Levine, M.; Horvath, S.; Haller, R. G.; Lenaers, G.; Wallace, D. C.; Tavazoie, S.; Procaccio, V.; Kaufman, B. A.; Seifert, E. L.; Hirano, M.; Picard, M.
10.1101/2021.11.29.470428 — cell biology — Posted on 2022-05-28
521 A Role for Nup153 in Nuclear Assembly Reveals Differential Requirements for Targeting of Nuclear Envelope Constituents
LaJoie, D.; Turkmen, A. M.; Mackay, D. R.; Jensen, C. C.; Aksenova, V.; Niwa, M.; Dasso, M.; Ullman, K. S.
10.1101/2022.05.27.493435 — cell biology — Posted on 2022-05-28
522 LUBAC assembles a signaling platform at mitochondria for signal amplification and shuttling of NF-ĸB to the nucleus
Wu, Z.; Berlemann, L. A.; Bader, V.; Sehr, D. A.; Eilers, E.; Covallero, A.; Meschede, J.; Angersbach, L.; Showkat, C.; Michaelis, J. B.; Muench, C.; Rieger, B.; Namgaladze, D.; Herrera, M. G.; Fiesel, F. C.; Springer, W.; Mendes, M.; Stepien, J.; Barkovits, K.; Marcus, K.; Sickmann, A.; Dittmar, G.; Busch, K. B.; Riedel, D.; Brini, M.; Tatzelt, J.; Cali, T.; Winklhofer, K. F.
10.1101/2022.05.27.493704 — cell biology — Posted on 2022-05-28
523 Single-cell perspectives on the function and development of deep-sea mussel bacteriocytes
Chen, H.; Li, M.; Wang, M.; Zhong, Z.; Lian, C.; Zhou, L.; Zhang, H.; Wang, H.; Cao, L.; Li, C.
10.1101/2022.05.28.493830 — molecular biology — Posted on 2022-05-28
525 Intestinal norovirus binding patterns in non-secretor individuals
Tarris, G.; Estienney, M.; Daval-Frerot, P.; Lariotte, A.-C.; Aubignat, D.; Se, K.; Michiels, C.; Martin, L.; de Rougemont, A.; Belliot, G.
10.1101/2022.05.26.493674 — microbiology — Posted on 2022-05-28
527 Highly-multiplexed serology for non-human mammals
Schuettenberg, A.; Pina, A.; Metrailer, M.; Pelaez-Sanchez, R. G.; Agudelo-Florez, P.; Alvaro Lopez, J.; Ryle, L.; Monroy, F. P.; Altin, J. A.; Ladner, J. T.
10.1101/2022.05.24.493290 — immunology — Posted on 2022-05-28
528 Kidney tubular epithelial cell ferroptosis links glomerular injury to tubulointerstitial pathology in lupus nephritis
Alli, A. A.; Desai, D.; Elshika, A.; Morel, L.; Conrad, M.; Proneth, B.; Clapp, W.; Atkinson, C.; Segal, M.; Searcy, L.; Denslow, N.; Bolisetty, S.; Mehrad, B.; Scindia, Y.
10.1101/2022.05.26.493579 — immunology — Posted on 2022-05-28
531 NFYA promotes the malignant behavior of triple-negative breast cancer through the regulation of lipid metabolism
Okada, N.; Ueki, C.; Shimazaki, M.; Tsujimoto, G.; Kohno, S.; Muranaka, H.; Yoshikawa, K.; Takahashi, C.
10.1101/2022.05.26.493660 — cancer biology — Posted on 2022-05-28
533 Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq
Replogle, J. M.; Saunders, R. A.; Pogson, A. N.; Hussmann, J. A.; Lenail, A.; Guna, A.; Mascibroda, L.; Wagner, E. J.; Adelman, K.; Lithwick-Yanai, G.; Iremadze, N.; Oberstrass, F.; Lipson, D.; Bonnar, J. L.; Jost, M.; Norman, T. M.; Weissman, J. S.
10.1101/2021.12.16.473013 — genomics — Posted on 2022-05-28
536 Genomic correlates for migratory direction in a free-ranging cervid
Bonar, M.; Anderson, S. J.; Anderson, C. R.; Wittemyer, G.; Northrup, J. M.; Shafer, A. B. A.
10.1101/2022.05.26.493590 — genomics — Posted on 2022-05-28
537 Whole exome-sequencing of vitiligo lesions indicate lower burden of somatic variations: implications in risk for non-melanoma skin cancers
Gupta, I.; Shankrit, S.; Narta, K.; Ghazi, M.; Grover, R.; Pandey, R.; Kar, H. K.; Menon, S. M.; Gupta, A.; Yenamandra, V. K.; Singh, A.; Mukerji, M.; Mukhopadhyay, A.; Rani, R.; Gokhale, R. S.; Natarajan, V. T.
10.1101/2022.05.28.493819 — genomics — Posted on 2022-05-28
538 Affinity-optimizing variants within the ZRS enhancer disrupt limb development
Lim, F.; Ryan, G. E.; Le, S. H.; Solvason, J. J.; Steffen, P.; Farley, E. K.
10.1101/2022.05.27.493789 — genetics — Posted on 2022-05-28
539 Secretoglobin family 1D member 2 (SCGB1D2) protein inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease
Strausz, S.; Blacker, G.; Galloway, S.; Hansen, P.; Jones, S.; Sanders, E.; Sinnott-Armstrong, N.; FinnGen, F.; Weissman, I. L.; Daly, M. J.; Aivelo, T.; Tal, M.; Ollila, H. M.
10.1101/2022.05.27.493784 — genetics — Posted on 2022-05-28
541 Low heritability of crossover rate in wild sticklebacks
Kivikoski, M.; Fraimout, A.; Rastas, P.; Löytynoja, A.; Merilä, J.
10.1101/2022.05.26.493536 — evolutionary biology — Posted on 2022-05-28
546 Specific Pupylation as IDEntity Reporter (SPIDER) for the identification of Protein-Biomolecule interactions
Jiang, H.-W.; Chen, H.; Zheng, Y.-X.; Wang, X.-N.; Meng, Q.; Xie, J.; Zhang, J.; Zhang, C.-S.; Xu, Z.-W.; Chen, Z.-Q.; Wang, L.; Kong, W.-S.; Zhou, K.; Ma, M.-L.; Zhang, H.-N.; Guo, S.-J.; Xue, J.-B.; Hou, J.-L.; Liu, Z.-Y.; Niu, W.-X.; Wang, F.-J.; Wang, T.; Li, W.; Wang, R.-N.; Dang, Y.-J.; Czajkowsky, D. M.; Qiao, Y.; Dong, J.-J.; Pei, J.; Tao, S.-C.
10.1101/2022.05.26.493537 — systems biology — Posted on 2022-05-28
548 The gradient-based parameter optimization to determine membrane ionic current composition of human induced pluripotent stem cell-derived cardiomyocytes
Kohjitani, H.; Koda, S.; Himeno, Y.; Makiyama, T.; Yamamoto, Y.; Yoshinaga, D.; Wuriyanghai, Y.; Kashiwa, A.; Toyoda, F.; Zhang, Y.; Amano, A.; Noma, A.; Kimura, T.
10.1101/2022.05.16.492203 — physiology — Posted on 2022-05-28
551 Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert tumor microenvironment and confers resistance to immunotherapy
Yan, J.; Chen, Y.; Patel, A. J.; Warda, S.; Nixon, B. G.; Wong, E. W. P.; Miranda-Roman, M. A.; Lee, C. J.; Yang, N.; Wang, Y.; Sher, J.; Giff, E.; Tang, F.; Khurana, E.; Singer, S.; Liu, Y.; Galbo, P. M.; Maag, J. L.; Koche, R. P.; Zheng, D.; Deng, L.; Antonescu, C. R.; Li, M.; Chen, Y.; Chi, P.
10.1101/2022.05.27.493507 — cancer biology — Posted on 2022-05-27
552 ALDH9A1 Deficiency as a Source of Endogenous DNA Damage that Requires Repair by the Fanconi Anemia Pathway
Jung, M.; Ilyashov, I.; Park, Y.; Donovan, F. X.; Ramanagoudr Bhojappa, R.; Keahi, D.; Durmaz, J. A.; Choijilsuren, H. B.; Goldfarb, A.; Stein, M.; Kim, J.; White, R. R.; Sridhar, S.; Noonan, R.; Wiley, T.; Carroll, T. S.; Lach, F. P.; Auerbach, A. D.; Miranda, I.; Chandrasekharappa, S. C.; Smogorzewska, A.
10.1101/2022.05.26.493623 — genetics — Posted on 2022-05-27
556 The evolution of two transmissible cancers in Tasmanian devils
Stammnitz, M. R.; Gori, K.; Kwon, Y. M.; Harry, E.; Martin, F. J.; Billis, K.; Cheng, Y.; Baez-Ortega, A.; Chow, W.; Comte, S.; Eggertsson, H.; Fox, S.; Hamede, R.; Jones, M. E.; Lazenby, B.; Peck, S.; Pye, R.; Quail, M. A.; Swift, K.; Wang, J.; Wood, J.; Howe, K.; Stratton, M. R.; Ning, Z.; Murchison, E. P.
10.1101/2022.05.27.493404 — cancer biology — Posted on 2022-05-27
557 Zur and Zinc Increase Expression of E. coli Ribosomal Protein L31 Through RNA-Mediated Repression of the Repressor L31p
Rasmussen, R. A.; Caramillo, J. M.; Sosnowski, V.; Cho, B.-K.; Goo, Y. A.; Lucks, J. B.; O'Halloran, T. V.
10.1101/2022.05.27.493739 — biochemistry — Posted on 2022-05-27
560 PAF1 and FACT cooperate with MLL-AF4 to drive enhancer activity in leukemia
Crump, N. T.; Smith, A.; Godfrey, L.; Jackson, N.; Rice, S.; Kim, J.; Basrur, V.; Fermin, D.; Elenitoba-Johnson, K.; Roeder, R. G.; Allis, C. D.; Roberts, I.; Roy, A.; Milne, T.
10.1101/2022.05.27.493676 — molecular biology — Posted on 2022-05-27
564 Type I interferon and MAVS signaling restricts chikungunya virus heart infection and cardiac tissue damage
Noval, M. G.; Bartnicki, E.; Spector, S. N.; Izzo, F.; Damani-Yokota, P.; Narula, N.; Yeung, S. T.; Rodriguez-Rodriguez, B. A.; Dewan, M. Z.; Mezzano, V.; Loomis, C.; Khanna, K. M.; Stapleford, K. A.
10.1101/2022.05.27.493768 — microbiology — Posted on 2022-05-27
565 FcRγ- NK cell induction by specific CMV and expansion by subclinical viral infections in rhesus macaques
Lee, J.; Chang, W.; Scott, J. M.; Hong, S.; Lee, T.; Deere, J. D.; Park, P.; Sparger, E. E.; Dandekar, S.; Hartigan-O'Connor, D.; Barry, P. A.; Kim, S.
10.1101/2022.05.26.493509 — immunology — Posted on 2022-05-27
568 Magneto-acoustic protein nanostructures for non-invasive imaging of tissue mechanics in vivo
Kim, W.-S.; Min, S.; Kim, S. K.; Kang, S.; Davis, H.; Bar-Zion, A.; Malounda, D.; Kim, Y. H.; An, S.; Lee, J.-H.; Bae, S. H.; Lee, J. G.; Kwak, M.; Cho, S.-W.; Shapiro, M. G.; Cheon, J.
10.1101/2022.05.26.493158 — biochemistry — Posted on 2022-05-27
569 Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance
Fazakerley, D. J.; van Gerwen, J.; Cooke, K. C.; Duan, X.; Needham, E. J.; Madsen, S.; Norris, D. M.; Shun-Shion, A. S.; Krycer, J. R.; Burchfield, J. G.; Yang, P.; Wade, M. R.; Brozinick, J. T.; James, D. E.; Humphrey, S. J.
10.1101/2022.05.26.493198 — molecular biology — Posted on 2022-05-27
570 Competition for cysteine acylation by C16:0 and C18:0 derived lipids is a global phenomenon in the proteome
Nuskova, H.; Garcia Cortizo, F.; Schwenker, L. S.; Tiebe, M.; Schneider, M.; Helm, D.; Reid, C.; Kopp-Schneider, A.; Miller, A.; Teleman, A. A.
10.1101/2022.05.27.492351 — molecular biology — Posted on 2022-05-27
571 In vivo reprogramming leads to premature death due to hepatic and intestinal failure.
Parras, A.; Vilchez-Acosta, A.; Desdin-Mico, G.; Mrabti, C.; Rechsteiner, C.; Battiston, F.; Branchina, C.; Perez, K.; Sempoux, C.; Ocampo, A.
10.1101/2022.05.27.493700 — molecular biology — Posted on 2022-05-27
573 HIV proviral genetic diversity, compartmentalization and inferred dynamics in lung and blood during long-term suppressive antiretroviral therapy
Shahid, A.; Jones, B. R.; Yang, J.; Dong, W.; Shaipanich, T.; Donohoe, K.; Brumme, C. J.; Joy, J. B.; Leung, J. M.; Brumme, Z. L.
10.1101/2022.05.26.493568 — molecular biology — Posted on 2022-05-27
577 A small DNA virus initiates replication with no more than three genome copies per cell
Ren, R.; Zheng, L.; Perdoncini Carvalho, C.; Han, J.; Miyashita, S.; Zhang, D.; Qu, F.
10.1101/2022.05.27.493787 — microbiology — Posted on 2022-05-27
579 Bacterial capsular polysaccharides with antibiofilm activity share common biophysical and electrokinetic properties
BAYARD-BERNAL, J.; THIEBAUD, J.; BROSSAUD, M.; BEAUSSART, A.; CAILLET, C.; WALDVOGEL, Y.; TRAVIER, L.; LETOFFE, S.; FONTAINE, T.; ROKBI, B.; TALAGA, P.; BELOIN, C.; MISTRETTA, N.; DUVAL, J. F. L.; GHIGO, J.-M.
10.1101/2022.05.27.493690 — microbiology — Posted on 2022-05-27
580 Within-host genotypic and phenotypic diversity of contemporaneous carbapenem-resistant Klebsiella pneumoniae from blood cultures of patients with bacteremia
Cheng, S.; Fleres, G.; Chen, L.; Liu, G.; Hao, B.; Newbrough, A.; Driscoll, E.; Shields, R. K.; Squires, K. M.; Chu, T.; Kreiswirth, B. N.; Nguyen, M. H.; Clancy, C. J.
10.1101/2022.05.26.493675 — microbiology — Posted on 2022-05-27
582 New Vista into Origins of Viruses from a Prototypic ssDNA Phage
Kejzar, N.; Laanto, E.; Rissanen, I.; Abrishami, V.; Selvaraj, M.; Moineau, S.; Ravantti, J.; Sundberg, L.-R.; Huiskonen, J. T.
10.1101/2022.05.27.493684 — microbiology — Posted on 2022-05-27
584 Design of a systemic small molecule clinical STING agonist using physics-based simulations and artificial intelligence
Allen, B. K.; Kulkarni, M. M.; Chamberlain, B.; Dwight, T.; Koh, C.; Samant, R.; Jernigan, F.; Rice, J.; Tan, D.; Li, S.; Marino, K.; Huang, H.; Chiswick, E.; Tesar, B.; Sparks, S.; Lin, Z.; McGee, T. D.; Kolossvary, I.; Lin, C.; Shechter, S.; Soutter, H.; Bastos, C.; Taimi, M.; Lai, S.; Petrin, A.; Kane, T.; Swann, S.; Gardner, H.; Winter, C.; Sherman, W.
10.1101/2022.05.23.493001 — cancer biology — Posted on 2022-05-27
585 The Glycan-Specificity of the Pineapple Lectin AcmJRL and its Carbohydrate-Dependent Binding of the SARS-CoV-2 Spike Protein
Meiers, J.; Dastbaz, J.; Adam, S.; Rasheed, S.; Kirsch, S. H.; Meiser, P.; Gross, P.; Mueller, R.; Titz, A.
10.1101/2022.05.27.493400 — biophysics — Posted on 2022-05-27
587 Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages
Li, X.; Pan, Y.; Yin, Q.; Wang, Z.; Shan, S.; Zhang, L.; Yu, J.; Qu, Y.; Sun, L.; Gui, F.; Lu, J.; Jing, Z.; Wu, W.; Huang, T.; Shi, X.; Li, J.; Li, X.; Li, D.; Wang, S.; Yang, M.; Zhang, L.; Duan, K.; Liang, M.; Yang, X.; Wang, X.
10.1101/2022.05.27.493682 — biochemistry — Posted on 2022-05-27
588 Stable antibiotic resistance and rapid human adaptation in livestock-associated MRSA
Matuszewska, M.; Murray, G. G. R.; Ba, X.; Wood, R.; Holmes, M. A.; Weinert, L. A.
10.1101/2021.08.20.457141 — evolutionary biology — Posted on 2022-05-27
591 ZNF692 organizes a hub for ribosome maturation enhancing translation in rapidly proliferating cells
Lafita-Navarro, M. C.; Hao, Y.-H.; Jiang, C.; Brown, I. N.; Jang, S.; Venkateswaran, N.; Maurais, E.; Stachera, W.; Chang, T.-C.; Mundy, D.; Han, J.; Han, J.; Tran, V. M.; Mettlen, M.; Woodruff, J. B. W. B.; Mendell, J. T.; Grishin, N. V.; Kinch, L.; Buszczak, M.; Conacci-Sorrell, M.
10.1101/2022.05.26.493655 — molecular biology — Posted on 2022-05-27
592 Ultra-sensitive Protein-SIP to quantify activity and substrate uptake in microbiomes with stable isotopes
Kleiner, M.; Kouris, A.; Jensen, M.; D'Angelo, G.; Liu, Y.; Korenek, A.; Tolic, N.; Sachsenberg, T.; McCalder, J.; Lipton, M. S.; Strous, M.
10.1101/2021.03.29.437612 — microbiology — Posted on 2022-05-27
593 Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery
Milazzo, F. M.; Chaves-Sanjuan, A.; Minenkova, O.; Santapaola, D.; Anastasi, A. M.; Battistuzzi, G.; Chiapparino, C.; Rosi, A.; Merlo Pich, E.; Albertoni, C.; Marra, E.; Luberto, L.; Viollet, C.; Spagnoli, L. G.; Riccio, A.; Rossi, A.; Santoro, M. G.; Ballabio, F.; Paissoni, C.; Camilloni, C.; Bolognesi, M.; De Santis, R.
10.1101/2022.05.27.493569 — microbiology — Posted on 2022-05-27
595 Ventral forebrain organoids derived from individuals with schizophrenia recapitulate perturbed striatal gene expression dynamics of the donor's brains
Sawada, T.; Barbosa, A.; Araujo, B.; McCord, A. E.; D'Ignazio, L.; Benjamin, K. J. M.; Feltrin, A.; Arora, R.; Brandtjen, A. C.; Kleinman, J. E.; Hyde, T. M.; Weinberger, D.; Paquola, A. C. M.; Erwin, J. A.
10.1101/2022.05.26.493589 — neuroscience — Posted on 2022-05-27
596 Accurate speech decoding requires high-resolution neural interfaces
Duraivel, S.; Rahimpour, S.; Chiang, C.-H.; Trumpis, M.; Wang, C.; Barth, K.; Lad, S. P.; Friedman, A. H.; Southwell, D. G.; Sinha, S. R.; Viventi, J.; Cogan, G. B.
10.1101/2022.05.19.492723 — neuroscience — Posted on 2022-05-27
598 A Chitin-Binding Protein Ultra-highly expressed in the Outer Fold of Mantle is Related to Shell Colour in Pacific Oyster Crassostrea gigas
Li, M.; Tang, J.; Huang, B.; Liu, Y.; Wei, L.; Han, Y.; Wang, X.; Sang, X.; Yuan, M.; Fan, N.; Cai, S.; Zheng, Y.; Zhang, M.; Wang, X.
10.1101/2022.04.18.488701 — physiology — Posted on 2022-05-27
599 Atomic-Resolution Prediction of Degrader-mediated Ternary Complex Structures by Combining Molecular Simulations with Hydrogen Deuterium Exchange
Dixon, T.; MacPherson, D.; Mostofian, B.; Dauzhenka, T.; Lotz, S.; McGee, D.; Shechter, S.; Shrestha, U.; Wiewiora, R.; McDargh, Z. A.; Pei, F.; Pal, R.; Ribeiro, J. V.; Wilkerson, T.; Sachdeva, V.; Gao, N.; Jain, S.; Sparks, S.; Li, Y.; Vinitsky, A.; Razavi, A. M.; Kolossvary, I.; Imbriglio, J.; Evdokimov, A.; Bergeron, L.; Zhou, W.; Adhikari, J.; Ruprecht, B.; Dickson, A.; Xu, H.; Sherman, W.; Izaguirre, J. A.
10.1101/2021.09.26.461830 — biophysics — Posted on 2022-05-27
603 Anthropogenic impacts on threatened species erode functional diversity in turtles and crocodilians
Rodriguez-Caro, R. C.; Gracia, E.; Blomberg, S. P.; Cayuela, H.; Grace, M.; Carmona, C. P.; Perez-Mendonza, H. A.; Gimenez, A.; Salguero-Gomez, R.
10.1101/2022.03.11.483822 — ecology — Posted on 2022-05-27
606 Substantial differences in soil viral community composition within and among four Northern California habitats
Durham, D. M.; Sieradzki, E. T.; ter Horst, A. M.; Santos-Medellin, C.; Bess, C. W. A.; Geonczy, S. E.; Emerson, J. B.
10.1101/2022.05.26.493654 — microbiology — Posted on 2022-05-27
607 Modernizing the NEURON Simulator for Sustainability, Portability, and Performance
Awile, O.; Kumbhar, P.; Cornu, N.; Dura-Bernal, S.; King, J. G.; Lupton, O.; Magkanaris, I.; McDougal, R. A.; Newton, A. J. H.; Pereira, F.; Savulescu, A.; Carnevale, N. T.; Lytton, W. W.; Hines, M. L.; Schürmann, F.
10.1101/2022.03.03.482816 — neuroscience — Posted on 2022-05-27
611 Basal forebrain cholinergic circuits orchestrate diverse cell types in the adult dentate gyrus to support neural stem cell function and spatial memory
Quintanilla, L.; Song, J.; Simon, J.; Li, Y.-D.; Asrican, B.; Tart, S.; Luo, Y.-J.; Su, Y.; Song, H.; Sheehy, R. N.; Ming, G.-L.
10.1101/2022.05.25.493227 — neuroscience — Posted on 2022-05-27
613 IDENTIFYING PLANT GENES SHAPING MICROBIOTA COMPOSITION IN THE BARLEY RHIZOSPHERE
Escudero-Martinez, C.; Coulter, M.; Alegria Terrazas, R.; Foito, A.; Kapadia, R.; Pietrangelo, L.; Maver, M.; Sharma, R.; Aprile, A.; Morris, J.; Hedley, P. E.; Maurer, A.; Pillen, K.; Naclerio, G.; Mimmo, T.; Barton, G. J.; Waugh, R.; Abbott, J.; Bulgarelli, D.
10.1101/2021.12.20.472907 — plant biology — Posted on 2022-05-27
615 Learning single-cell chromatin accessibility profiles using meta-analytic marker genes
Kawaguchi, R. K.; Tang, Z.; Fischer, S.; Rajesh, C.; Tripathy, R.; Koo, P. K.; Gillis, J.
10.1101/2021.04.01.438068 — bioinformatics — Posted on 2022-05-27
620 Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids
Vanslambrouck, J. M.; Wilson, S. B.; Tan, K. S.; Groenewegen, E.; Rudraraju, R.; Neil, J.; Lawlor, K. T.; Mah, S.; Scurr, M.; Howden, S. E.; Subbarao, K.; Little, M. H.
10.1101/2021.10.14.464320 — bioengineering — Posted on 2022-05-27
621 A global pangenome for the wheat fungal pathogen Pyrenophora tritici-repentis and prediction of effector protein structural homology
Moolhuijzen, P. M.; See, P. T.; Shi, G.; Powell, H. R.; Cockram, J.; Jorgensen, L. N.; Benslimane, H.; Strelkov, S. E.; Turner, J.; Liu, Z.; Moffat, C. S.
10.1101/2022.03.07.482416 — genomics — Posted on 2022-05-27
623 A CRISPR-del-based pipeline for complete gene knockout in human diploid cells
Komori, T.; Hata, S.; Mabuchi, A.; Genova, M.; Harada, T.; Fukuyama, M.; Chinen, T.; Kitagawa, D.
10.1101/2021.06.21.449335 — cell biology — Posted on 2022-05-27
626 Organisation of gene programs revealed by unsupervised analysis of diverse gene-trait associations
Mizikovsky, D.; Naval Sanchez, M.; Nefzger, C. M.; Cuellar Partida, G.; Palpant, N.
10.1101/2022.04.07.487559 — genomics — Posted on 2022-05-27
627 Intranasal vaccination induced cross-protective secretory IgA antibodies against SARS-CoV-2 variants with reducing the potential risk of lung eosinophilic immunopathology
Hemmi, T.; Ainai, A.; Hashiguchi, T.; Tobiume, M.; Kanno, T.; Iwata-Yoshikawa, N.; Iida, S.; Sato, Y.; Miyamoto, S.; Ueno, A.; Sano, K.; Saito, S.; Shiwa-Sudo, N.; Nagata, N.; Tamura, K.; Suzuki, R.; Hasegawa, H.; Suzuki, T.
10.1101/2022.05.24.493348 — microbiology — Posted on 2022-05-27
629 Quantifying individual base stacking energies with the Centrifuge Force Microscope
Punnoose, J. A.; Thomas, K. J.; Chandrasekaran, A. R.; Vilcapoma, J.; Hayden, A.; Banco, T.; Halvorsen, K.
10.1101/2022.05.25.493108 — biophysics — Posted on 2022-05-27
630 Spatial-ID: a cell typing method for spatially resolved transcriptomics via transfer learning and spatial embedding
Shen, R.; Liu, L.; Wu, Z.; Zhang, Y.; Yuan, Z.; guo, j.; Yang, F.; Zhang, C.; Chen, B.; Liu, C.; Guo, J.; Fan, G.; Zhang, Y.; Li, Y.; Xu, X.; Yao, J.
10.1101/2022.05.26.493527 — genomics — Posted on 2022-05-27
631 Morphodynamic Atlas for Drosophila Development
Mitchell, N. P.; Lefebvre, M. F.; Jain-Sharma, V.; Claussen, N. H.; Raich, M. K.; Gustafson, H. J.; Bausch, A.; Streichan, S. J.
10.1101/2022.05.26.493584 — developmental biology — Posted on 2022-05-27
632 The exocyst complex is an essential component of the mammalian constitutive secretory pathway
Pereira, C.; Stalder, D.; Anderson, G.; Shun-Shion, A. S.; Houghton, J.; Antrobus, R.; Chapman, M. A.; Fazakerley, D. J.; Gershlick, D. C.
10.1101/2022.05.26.493223 — cell biology — Posted on 2022-05-27
633 Signaling dynamics distinguish high and low priority neutrophil attractant receptors
Lundgren, S. M.; Rocha-Gregg, B. L.; Akdogan, E.; Mysore, M. N.; Hayes, S. L.; Collins, S. R.
10.1101/2022.05.26.493652 — cell biology — Posted on 2022-05-27
637 The ultradian transcriptome of the human prefrontal cortex and abnormalities in schizophrenia
Scott, M. R.; Zong, W.; Ketchesin, K. D.; Seney, M. L.; Tseng, G.; Zhu, B.; McClung, C. A.
10.1101/2022.05.26.493559 — neuroscience — Posted on 2022-05-26
638 Population History and Genome Wide Association Studies of Birth Weight in a Native High Altitude Ladakhi Population
Bhandari, S.; Dolma, P.; Mukerji, M.; Prasher, B.; Montgomery, H.; Kular, D.; Jain, V.; Dadhwal, V.; Williams, D. J.; Bhattacharyaa, A.; Gilbert, E.; Cavalleri, G.; Hillman, S.
10.1101/2022.05.26.493635 — genetics — Posted on 2022-05-26
639 Optimum time for hand pollination in yam (Dioscorea spp.)
Mondo, J. M.; AGRE, P.; Asiedu, R.; Akoroda, M. O.; Asfaw, A.
10.1101/2022.05.26.493634 — plant biology — Posted on 2022-05-26
642 CRISPR base editing of cis-regulatory elements enables target gene perturbations
Lim, C. K. W.; McCallister, T. X.; Saporito-Magrina, C.; McPheron, G. D.; Krishnan, R.; Zeballos, M. A.; Powell, J. E.; Clark, L. V.; Perez-Pinera, P.; Gaj, T.
10.1101/2022.05.26.493649 — bioengineering — Posted on 2022-05-26
643 O-GlcNAc transferase plays a non-catalytic role in C. elegans male fertility
Konzman, D.; Fukushige, T.; Dagnachew, M.; Krause, M.; Hanover, J. A.
10.1101/2022.05.26.493566 — genetics — Posted on 2022-05-26
644 Mouse NEMP1 is required for erythropoiesis, nuclear envelope openings and enucleation of erythroblasts
Hodzic, D.; Wu, J.; Krchma, K.; Jurisicova, A.; Tsatskis, Y.; Liu, Y.; Ji, P.; Choi, K.; McNeill, H.
10.1101/2022.05.26.493585 — cell biology — Posted on 2022-05-26
646 Uncoupling from transcription protects polyadenylation site cleavage from inhibition by DNA damage
Sfaxi, R.; Biswas, B.; Boldina, G.; Cadix, M.; Servant, N.; Chen, H.; Larson, D. R.; Dutertre, M.; Robert, C.; Vagner, S.
10.1101/2022.05.26.492040 — molecular biology — Posted on 2022-05-26
648 Programmable RNA Sensing for Cell Monitoring and Manipulation
Qian, Y.; Li, J.; Zhao, S.; Matthews, E. A.; Adoff, M.; Zhong, W.; An, X.; Yeo, M.; Park, C.; Wang, B.-S.; Southwell, D. G.; Huang, Z. J.
10.1101/2022.05.25.493141 — molecular biology — Posted on 2022-05-26
649 Gut feelings: Associations of emotions and emotion regulation with the gut microbiome in women
Ke, S.; Guimond, A.-J.; Tworoger, S.; Huang, T.; Chan, A. T.; Liu, Y.-Y.; Kubzansky, L. D.
10.1101/2022.05.26.493641 — microbiology — Posted on 2022-05-26
650 Bridging the gap between bioinformatics and the clinical and public health microbiology laboratory: An ISO-accredited genomics workflow for antimicrobial resistance
Sherry, N. L.; Horan, K.; Ballard, S. A.; Goncalves da Silva, A.; Gorrie, C. L.; Schultz, M. B.; Stevens, K.; Valcanis, M.; Sait, M.; Stinear, T. P.; Howden, B. P.; Seemann, T.
10.1101/2022.05.26.493552 — microbiology — Posted on 2022-05-26
652 Coordination of CcpA and CodY regulators in Staphylococcus aureus USA300 strains
Poudel, S.; Hefner, Y.; Szubin, R.; Sastry, A. V.; Gao, Y.; Nizet, V.; Palsson, B. O.
10.1101/2022.05.25.493525 — microbiology — Posted on 2022-05-26
654 Functional geometry of auditory cortical resting state networks derived from intracranial electrophysiology
Banks, M. I.; Krause, B. M.; Berger, D. G.; Campbell, D. I.; Boes, A. D.; Bruss, J. E.; Kovach, C. K.; Kawasaki, H.; Steinschneider, M.; Nourski, K. V.
10.1101/2022.02.06.479292 — neuroscience — Posted on 2022-05-26
656 Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology
Bhatia^, H.; Larsson^, A. T.; Calizo^, A.; Pollard, K.; Zhang, X.; Conniff, E.; Tibbitts, J. F.; Osum, S. H.; Williams, K. B.; Crampton, A. L.; Jubenville, T.; Schefer, D.; Yang, K.; Lyu, Y.; Bade, J.; Pino, J. C.; Gosline, S. J.; Pratilas, C. A.; Largaespada, D. A.; Wood, D. K.; Hirbe, A. C.
10.1101/2022.04.29.490078 — cancer biology — Posted on 2022-05-26
658 Peptide and protein alphavirus antigens for broad spectrum vaccine design
Schein, C. H.; Schmidt, J. G.; Braun, W.; Weaver, S.; Baker, W. S.; Rafael, G.; Negi, S. S.
10.1101/2022.05.26.493643 — bioengineering — Posted on 2022-05-26
661 The amino acid transporter pfaat1 modulates chloroquine resistance and fitness in malaria parasites
Amambua-Ngwa, A.; Button-Simons, K. A.; Li, X.; Kumar, S.; Brenneman, K. V.; Ferrari, M.; Checkley, L. A.; Haile, M. T.; Shoue, D. A.; McDew-White, M.; Tindall, S. M.; Reyes, A.; Delgado, E.; Dahlhoff, H.; Larbalestier, J. K.; Amato, R.; Pearson, R. D.; Taylor, A. B.; Nosten, F. H.; D'Alessandro, U.; Kwiatkowski, D.; Cheeseman, I. H.; Kappe, S. H. I.; Avery, S. V.; Conway, D. J.; Vaughan, A. M. V.; Ferdig, M. T.; Anderson, T. J. C.
10.1101/2022.05.26.493611 — genomics — Posted on 2022-05-26
664 The budding yeast heterochromatic protein Sir3 is a global modulator of gene expression
Bhattacharjee, P.; Galic, H.; Hrgovcic, A.; Camasses, A.; Demont, L.; Vasseur, P.; Radman-Livaja, M.
10.1101/603613 — molecular biology — Posted on 2022-05-26
665 A dual role for the RNA helicase DHX34 in NMDand pre-mRNA splicing and its function inhematopoietic differentiation
Hug, N.; Aitken, S.; Longman, D.; Raab, M.; Armes, H.; Mann, A. R.; Rio-Machin, A.; Fitzgibbon, J.; Rouault-Pierre, K.; Caceres, J. F.
10.1101/2022.05.26.492072 — molecular biology — Posted on 2022-05-26
667 Substantial differences in soil viral community composition within and among four Northern California habitats
Durham, D. M.; Sieradzki, E. T.; ter Horst, A. M.; Santos-Medellin, C.; Bess, C. W. A.; Geonczy, S. E.; Emerson, J. B.
10.1101/2022.05.26.493654 — microbiology — Posted on 2022-05-26
669 Pseudomonas aeruginosa contracts mucus to rapidly form biofilms in tissue-engineered human airways
Rossy, T.; Distler, T.; Pezoldt, J.; Kim, J.; Tala, L.; Bouklas, N.; Deplancke, B.; Persat, A.
10.1101/2022.05.26.493615 — microbiology — Posted on 2022-05-26
670 Vertical and horizontal transmission of cell fusing agent virus in Aedes aegypti
Logan, R. A.; Quek, S.; Muthoni, J. N.; von Eicken, A.; Brettell, L. E.; Anderson, E. R.; Villena, M. E.; Hegde, S.; Patterson, G. T.; Heinz, E.; Hughes, G.; Patterson, E. I.
10.1101/2022.05.26.493619 — microbiology — Posted on 2022-05-26
672 Intraoperative electrical stimulation of the human dorsal spinal cord reveals a map of arm and hand muscle responses
McIntosh, J. R.; Joiner, E. F.; Goldberg, J. L.; Murray, L. M.; Yasin, B.; Mendiratta, A.; Karceski, S. C.; Thuet, E.; Modik, O.; Shelkov, E.; Lombardi, J. M.; Sardar, Z. M.; Lehman, R. A.; Mandigo, C.; Riew, K. D.; Harel, N. Y.; Virk, M. S.; Carmel, J. B.
10.1101/2022.01.29.478182 — neuroscience — Posted on 2022-05-26
673 Functional network properties derived from widefield calcium imaging differ with wakefulness and across cell type
O'Connor, D.; Mandino, F.; Shen, X.; Horien, C.; Ge, X.; Herman, P.; Crair, M.; Papademetris, X.; Lake, E. M.; Constable, R. T.
10.1101/2022.05.24.493310 — neuroscience — Posted on 2022-05-26
676 Structural Basis of Mutation-Dependent p53 Tetramerization Deficiency
Rigoli, M.; Spagnolli, G.; Lorengo, G.; Monti, P.; Potestio, R.; Biasini, E.; Inga, A.
10.1101/2022.05.13.491836 — cancer biology — Posted on 2022-05-26
681 Genetic characterisation of the Theileria annulata cytochrome b locus and its impact on buparvaquone resistance in ruminants
Ali, Q.; Zahid, O.; Mhadhbi, M.; Jones, B.; Darghouth, M. A.; Raynes, G.; Afshan, K.; Birtles, R.; Sargison, N. D.; Betson, M.; Chaudhry, U.
10.1101/2022.05.25.493409 — microbiology — Posted on 2022-05-26
682 Highly-multiplexed serology for non-human mammals
Schuettenberg, A.; Pina, A.; Metrailer, M.; Pelaez-Sanchez, R. G.; Agudelo-Florez, P.; Alvaro Lopez, J.; Ryle, L.; Monroy, F. P.; Altin, J. A.; Ladner, J. T.
10.1101/2022.05.24.493290 — immunology — Posted on 2022-05-26
685 Neural representations of vicarious rewards are linked to interoception and prosocial behaviour
Contreras-Huerta, L. S.; Coll, M.-P.; Bird, G.; Yu, H.; Prosser, A.; Lockwood, P. L.; Murphy, J.; Crockett, M. J.; Apps, M. A. J.
10.1101/2022.03.04.482889 — neuroscience — Posted on 2022-05-26
688 The emergence of variants with increased fitness accelerates the slowdown of genome sequence heterogeneity in the SARS CoV 2 coronavirus
Oliver, J. L.; Bernaola-Galvan, P.; Perfectti, F.; Gomez-Martin, C.; Castiglione, S.; Raia, P.; Verdu, M.; Moya, A.
10.1101/2022.05.26.493529 — genomics — Posted on 2022-05-26
689 Inhibition of major histocompatibility complex-I antigen presentation by sarbecovirus ORF7a proteins
Zhang, F.; Zang, T.; Stevenson, E. M.; Lei, X.; Copertino, D. C.; Mota, T. M.; Boucau, J.; Garcia-Beltran, W. F.; Jones, R. B. F.; Bieniasz, P. D.
10.1101/2022.05.25.493467 — microbiology — Posted on 2022-05-26
690 SARS-CoV-2 Omicron BA.2.12.1, BA.4, and BA.5 subvariants evolved to extend antibody evasion
Wang, Q.; Guo, Y.; Iketani, S.; Li, Z.; Mohri, H.; Wang, M.; Yu, J.; Bowen, A. D.; Chan, J. Y.; Shah, J. G.; Nguyen, N.; Meyers, K.; Yin, M. T.; Sobieszczyk, M. E.; Sheng, Z.; Huang, Y.; Liu, L.; Ho, D.
10.1101/2022.05.26.493517 — microbiology — Posted on 2022-05-26
691 Virological characteristics of the novel SARS-CoV-2 Omicron variants including BA.2.12.1, BA.4 and BA.5
Kimura, I.; Yamasoba, D.; Tamura, T.; Nao, N.; Oda, Y.; Mitoma, S.; Ito, J.; Nasser, H.; Zahradnik, J.; Uriu, K.; Fujita, S.; Kosugi, Y.; Wang, L.; Tsuda, M.; Kishimoto, M.; Ito, H.; Suzuki, R.; Shimizu, R.; Begum, M. M.; Yoshimatsu, K.; Sasaki, J.; Sasaki-Tabata, K.; Yamamoto, Y.; Nagamoto, T.; Kanamune, J.; Kobiyama, K.; Asakura, H.; Nagashima, M.; Sadamasu, K.; Yoshimura, K.; Kuramochi, J.; Schreiber, G.; Ishii, K. J.; Hashiguchi, T.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Ikeda, T.; Saito, A.; Fukuhara, T.; Tanaka, S.; Matsuno, K.; Sato, K.
10.1101/2022.05.26.493539 — microbiology — Posted on 2022-05-26
693 Rapid and precise genome engineering in a naturally short-lived vertebrate
Nath, R. D.; Bedbrook, C. N.; Nagvekar, R.; Deisseroth, K.; Brunet, A.
10.1101/2022.05.25.493454 — genetics — Posted on 2022-05-26
696 Saccadic modulation of neural excitability in auditory areas of the neocortex
Leszczynski, M.; Bickel, S.; Nentwich, M.; Russ, B. E.; Parra, L.; Lakatos, P.; Mehta, A.; Schroeder, C. E.
10.1101/2022.05.24.493336 — neuroscience — Posted on 2022-05-26
699 Insulin sensitivity is preserved in mice made obese by feeding a high starch diet
Brandon, A. E.; Small, L.; Nguyen, T.-V.; Suryana, E.; Gong, H.; Yassmin, C.; Hancock, S. E.; Pulpitel, T.; Stonehouse, S.; Prescott, L.; Kebede, M. A.; Yau, B.; Quek, L.-E.; Kowalski, G. M.; Bruce, C.; Turner, N.; Cooney, G. J.
10.1101/2022.05.25.493410 — physiology — Posted on 2022-05-26
700 Spinosaurus is not an aquatic dinosaur
Sereno, P. C.; Myhrvold, N.; Henderson, D. M.; Fish, F. E.; Vidal, D.; Baumgart, S. L.; Keillor, T. M.; Formoso, K. K.; Conroy, L. L.
10.1101/2022.05.25.493395 — paleontology — Posted on 2022-05-26
702 Microphase separation of living cells
Carrere, A.; d'Alessandro, J.; Cochet-Escartin, O.; Hesnard, J.; Ghazi, N.; Anjard, C.; Detcheverry, F.; Rieu, J.-P.
10.1101/2022.05.25.493184 — biophysics — Posted on 2022-05-26
703 ADOPT: intrinsic protein disorder prediction through deep bidirectional transformers
Tamiola, K.; Fisicaro, C.; Dutton, O.; Hoffmann, F.; Henderson, L.; Owens, B. M. J.; Heberling, M.; Redl, I.
10.1101/2022.05.25.493416 — bioinformatics — Posted on 2022-05-26
706 Intraprocedural endothelial cell seeding of arterial stents via biotin/avidin targeting mitigates in-stent restenosis
Alferiev, I. S.; Hooshdaran, B.; Pressly, B. B.; Stachelek, S. J.; Zoltick, P. W.; Chorny, M.; Levy, R. J.; Fishbein, I.
10.1101/2022.05.25.493423 — bioengineering — Posted on 2022-05-26
710 UNDESRTANDING MESENCHYMAL STEM CELL IMMUNE POTENCY:A MORPHOLOMIC AND LIPIDOMIC PERSPECTIVE
PRIYADARSHANI, P.; DeVeaux, S.; Leitmann, B.; Rui, K.; Botchwey, E.; Mortensen, L. J.
10.1101/2022.05.25.493514 — cell biology — Posted on 2022-05-26
711 Antiviral activity of the hemolymph of Podalia sp and M. albicolis (Lepidoptera: Megalopigydae)
Carvalho, N. D.; Curti, S. P.; Oliveira, M. I.; Rofatto, H. K.; Figueiredo, C. A.; Sena de Villar, K.; Magnelli, R. F.; Mendonca, R. Z.
10.1101/2022.05.25.493399 — microbiology — Posted on 2022-05-26
713 The central autonomic system revisited - convergent evidence for a regulatory role of the insular and midcingulate cortex from neuroimaging meta-analyses
Ferraro, S.; Klugah-Brown, B.; Tench, C.; Chepngetich Bore, M.; Nigri, A.; Bruzzone, M. G.; Demichelis, G.; Palermo, S.; Kendrick, K. M.; Jiang, X.; Yao, S.; Zhao, W.; Becker, B.
10.1101/2022.05.25.493371 — neuroscience — Posted on 2022-05-26
719 Obesity-Associated Alterations In Lung Function In Mice Measured With Head-Out Plethysmography
Bruggink, S.; Pederson, W. P.; Kentch, K. P.; Kronenfeld, J. M.; Ledford, J. G.; Renquist, B. J.
10.1101/2022.05.25.493464 — physiology — Posted on 2022-05-26
721 A Spatial Attention Guided Deep Learning System for Prediction of Pathological Complete Response Using Breast Cancer Histopathology Images
Duanmu, H.; Bhattarai, S.; Li, H.; Zhan, S.; Wang, F.; Teodoro, G.; Gogineni, K.; Subhedar, P.; Kiraz, U.; Janssen, E. A. M.; Aneja, R.; Kong, J.
10.1101/2022.05.25.493468 — bioinformatics — Posted on 2022-05-26
722 Using Extracellular Vesicles Released by GDNF-transfected Macrophages for Therapy of Parkinson's Disease
Zhao, Y.; Haney, M. J.; Fallon, J. K.; Rodriguez, M.; Swain, C.; Artz, C. J.; Smith, P. C.; Loop, M. S.; Harrison, E. B.; El-Hage, N.; Batrakova, E. V.
10.1101/2022.05.25.493424 — bioengineering — Posted on 2022-05-26
729 Coregistered transcranial optoacoustic and magnetic resonance angiography of the human brain
Ni, R.; Dean Ben, X. L.; Treyer, V.; Gietl, A.; Hock, C.; Klohs, J.; Nitsch, R. M.; Razansky, D.
10.1101/2022.05.24.492943 — neuroscience — Posted on 2022-05-26
730 Color-biased regions in the ventral visual pathway are food-selective
Pennock, I. M. L.; Racey, C.; Allen, E. J.; Wu, Y.; Naselaris, T.; Kay, K.; Franklin, A.; Bosten, J.
10.1101/2022.05.25.493425 — neuroscience — Posted on 2022-05-26
731 Microenvironmental Ammonia Enhances T cell Exhaustion in Colorectal Cancer
Shah, Y. M.; Bell, H.; Huber, A. K.; Singhal, R.; Rebernick, R. J.; Kumar, R.; Das, N. K.; Kerk, S. A.; Sajjakulnukit, P.; Solanki, S.; James, J. G.; Kim, D.; Zhang, L.; El-derany, M. O.; Frankel, T. L.; Gyorffy, B.; Fearon, E. R.; Pasca di Magliano, M.; Gonzalez, F. J.; Banerjee, R.; Lyssiotis, C. A.; Green, M.
10.1101/2022.05.25.493422 — cancer biology — Posted on 2022-05-26
732 Pleiotropic fitness effects of the lncRNA Uhg4 in Drosophila melanogaster
MacPherson, R. A.; Shankar, V.; Sunkara, L. T.; Hannah, R. C.; Campbell, M. R.; Anholt, R. R. H.; Mackay, T. F. C.
10.1101/2022.05.26.493587 — genomics — Posted on 2022-05-26
737 Specific Pupylation as IDEntity Reporter (SPIDER) for the identification of Protein-Biomolecule interactions
Jiang, H.-W.; Chen, H.; Zheng, Y.-X.; Wang, X.-N.; Meng, Q.; Xie, J.; Zhang, J.; Zhang, C.-S.; Xu, Z.-W.; Chen, Z.-Q.; Wang, L.; Kong, W.-S.; Zhou, K.; Ma, M.-L.; Zhang, H.-N.; Guo, S.-J.; Xue, J.-B.; Hou, J.-L.; Liu, Z.-Y.; Niu, W.-X.; Wang, F.-J.; Wang, T.; Li, W.; Wang, R.-N.; Dang, Y.-J.; Czajkowsky, D. M.; Qiao, Y.; Dong, J.-J.; Pei, J.; Tao, S.-C.
10.1101/2022.05.26.493537 — systems biology — Posted on 2022-05-26
740 Integrative metabolomics reveal the organisation of alkaloid biosynthesis in Daphniphyllum macropodum
Eljounaidi, K.; Radzikowska, B.; Whitehead, C.; Conde, S.; Davis, W.; Dowle, A.; Langer, S.; Larson, T.; Unsworth, W. P.; Ezer, D.; Lichman, B. R.
10.1101/2022.05.25.493403 — plant biology — Posted on 2022-05-26
749 Metadata retrieval from sequence databases with ffq
Galvez-Merchan, A.; Min, K. H.; Pachter, L.; Booeshaghi, A. S.
10.1101/2022.05.18.492548 — bioinformatics — Posted on 2022-05-26
750 Coenzyme A binding sites induce proximal acylation across protein families
Carrico, C.; Cruz, A.; Walter, M.; Meyer, J. G.; Wehrfritz, C.; Shah, S.; Wei, L.; Schilling, B.; Verdin, E.
10.1101/2022.05.24.493335 — biochemistry — Posted on 2022-05-26
752 Sen1 is a key regulator of transcription-driven conflicts
Aiello, U.; Challal, D.; Wentzinger, G.; Lengronne, A.; Appanah, R.; Pasero, P.; Palancade, B.; Libri, D.
10.1101/2022.02.09.479708 — genomics — Posted on 2022-05-26
754 An essential periplasmic protein coordinates lipid trafficking and is required for asymmetric polar growth in mycobacteria
Gupta, K. R.; Gwin, C. M.; Rahlwes, K. C.; Biegas, K. J.; Wang, C.; Park, J. H.; Liu, J.; Swarts, B. M.; Morita, Y. S.; Rego, E. H.
10.1101/633768 — microbiology — Posted on 2022-05-26
755 Aspergillus fumigatus can display persistence to the fungicidal drug voriconazole
Scott, J.; Valero, C.; Mato-Lopez, A.; Donaldson, I. J.; Roldan, A.; Chown, H.; Van-Rhijn, N.; Gago, S.; Furukawa, T.; Morogovsky, A.; Ben Ami, R.; Bowyer, P.; Osherov, N.; Fontaine, T.; Goldman, G. H.; Mellado, E.; Bromley, M.; Amich, J.
10.1101/2022.05.16.491816 — microbiology — Posted on 2022-05-26
757 Fronto-parietal networks shape human conscious report through attention gain and reorienting
Liu, J.; Bayle, D. J.; Spagna, A.; Sitt, J. D.; Bourgeois, A.; Lehongre, K.; Fernandez-Vidal, S.; Adam, C.; Lambrecq, V.; Navarro, V.; Malkinson, T. S.; Bartolomeo, P.
10.1101/2022.04.10.487690 — neuroscience — Posted on 2022-05-26
758 The bHLH transcription factor MpHYPNOS regulates gemma dormancy in the liverwort Marchantia polymorpha
Kato, H.; Yoshimura, N.; Yoshikawa, M.; Matsuura, H.; Takahashi, K.; Takezawa, D.; Furuya, T.; Kondo, Y.; Fukaki, H.; Mimura, T.; Ishizaki, K.
10.1101/2022.04.25.488978 — plant biology — Posted on 2022-05-26
759 Multiplexed Single-Molecule Epigenetic Analysis of Plasma-Isolated Nucleosomes for Cancer Diagnostics
Fedyuk, V.; Erez, N.; Furth, N.; Beresh, O.; Jones, D.; Shinde, A.; Andreishcheva, K.; Zakai, B. B.; Mavor, Y.; Peretz, T.; Hubert, A.; Cohen, J. E.; Salah, A.; Temper, M.; Grinshpun, A.; Maoz, M.; Zick, A.; Ron, G.; Shema, E.
10.1101/2021.11.01.466724 — cancer biology — Posted on 2022-05-26
760 THE ROLE OF POTASSIUM CHANNELS IN THE PATHOGENESIS OF GASTROINTESTINAL CANCERS AND THERAPEUTIC POTENTIAL
Shorthouse, D.; Zhuang, J. L.; Rahrmann, E.; Kosmidou, C.; Rahrmann, K. W.; Hall, M. W. J.; Greenwood, B.; Devonshire, G.; Gilbertson, R.; Fitzgerald, R.; Hall, B. A.
10.1101/2020.03.10.984039 — cancer biology — Posted on 2022-05-26
761 The Dct-/- mouse model to unravel retinogenesis misregulation in patients with albinism
Tingaud-Sequeira, A.; Mercier, E.; Michaud, V.; Pinson, B.; Gazova, I.; Gontier, E.; Decoeur, F.; McKie, L.; Jackson, I. J.; Arveiler, B.; Javerzat, S.
10.1101/2022.05.25.493436 — genetics — Posted on 2022-05-26
764 TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development
Feng, J.; Han, X.; Yuan, Y.; Cho, C. K.; Janeckova, E.; Guo, T.; Pareek, S.; Bi, J.; Jing, J.; Zhang, M.; Ho, T.-V.; Chai, Y.
10.1101/2022.05.25.493396 — developmental biology — Posted on 2022-05-26
765 Type I Interferon Signaling Drives Microglial Dysfunction and Senescence in Human iPSC Models of Down Syndrome and Alzheimers Disease
Jin, M.; Xu, R.; Wang, L.; Alam, M. M.; Ma, Z.; Zhu, S.; Martini, A. C.; Jadali, A.; Bernabucci, M.; Xie, P.; Kwan, K.; Pang, Z. P.; Head, E.; Liu, Y.; Hart, R. P.; Jiang, P.
10.1101/2021.12.22.473858 — neuroscience — Posted on 2022-05-26
766 Integration of imaging modalities with lipidomic characterization to investigate MSCs potency metrics
Mortensen, L. J.; Priyadarshani, P.; Van Grouw, A. R.; Liversage, A. R.; Nikitina, A. A.; Tehrani, K. F.; Kemp, M. L.; Fernandez, F.
10.1101/2022.05.25.493259 — cell biology — Posted on 2022-05-26
767 Tissue libraries enable rapid determination of conditions that preserve antibody labeling in cleared mouse and human tissue
Zwang, T. J.; Bennett, R. E.; Lysandrou, M.; Woost, B.; Zhang, A.; Lieber, C. M.; Richardson, D. S.; Hyman, B. T.
10.1101/2022.05.25.493465 — cell biology — Posted on 2022-05-26
768 Cardiac fibroblasts regulate cardiomyocyte hypertrophy through dynamic regulation of type I collagen
Meng, Q.; Bowers, S. L. K.; Kuwabara, Y.; Huo, J.; Minerath, R.; York, A. J.; Sargent, M. A.; Prasad, V.; Saviola, A. J.; Galindo, D. C.; Hansen, K. C.; Vagnozzi, R. J.; Yutzey, K. E.; Molkentin, J. D.
10.1101/2022.05.25.493406 — cell biology — Posted on 2022-05-26
769 An interaction between betaprime-COP and the ArfGAP, Glo3, maintains post-Golgi cargo recycling
Xie, B.; Guillem, C.; Jung, C.; Kendall, A. K.; Date, S.; Best, J. T.; Graham, T. R.; Jackson, L. P.
10.1101/2022.05.25.493481 — cell biology — Posted on 2022-05-26
773 Unique genomic sequences in novel Mycobacterium avium subsp. hominissuis lineage enabled fine scale tracing the transmission route during pig movement
Komatsu, T.; Ohya, K.; Ota, A.; Nishiuchi, Y.; Yano, H.; Matsuo, K.; Odoi, J. O.; Suganuma, S.; Sawai, K.; Hasebe, A.; Asai, T.; Yanai, T.; Fukushi, H.; Wada, T.; Yoshida, S.; Arikawa, K.; Ito, T.; Kawai, M.; Ato, M.; Baughn, A. D.; Iwamoto, T.; MARUYAMA, F.
10.1101/2022.04.04.487006 — microbiology — Posted on 2022-05-25
774 γ-Protocadherins control synapse formation and peripheral branching of touch sensory neurons
Meltzer, S.; Comeau, K.; Chirila, A.; Osei-Asante, E.; DeLisle, M.; Zhang, Q.; Kalish, B. T.; Tasnim, A.; Huey, E.; Fuller, L. C.; Flaherty, E. K.; Lefebvre, J. L.; Maniatis, T.; Garrett, A. M.; Weiner, J. A.; Ginty, D. D.
10.1101/2022.05.25.493080 — neuroscience — Posted on 2022-05-25
776 Variation in glutamate and GABA genes and their association with brain structure and chemistry in autism
Naaijen, J.; Arenella, M.; Zoellner, H. J.; Puts, N.; Lythgoe, D. J.; Brandeis, D.; Durston, S.; Poelmans, G.; Ruisch, I. H.; Buitelaar, J. K.
10.1101/2022.05.25.493390 — neuroscience — Posted on 2022-05-25
781 Ferric reductase-related proteins mediate fungal heme acquisition
Roy, U.; Yaish, S.; Weissman, Z.; Pinsky, M.; Dey, S.; Horev, G.; Kornitzer, D.
10.1101/2022.05.25.493415 — microbiology — Posted on 2022-05-25
783 Broad Recognition of Mamu-Bw4 and -A-related MHC class I Ligands by Rhesus Macaque Killer-Cell Immunoglobulin-Like Receptors
Anderson, J. L.; Sandstrom, K.; Nicholas, R. E.; Smith, W. R.; Wetzel, M.; Klenchin, V. A.; Evans, D. T.
10.1101/2022.05.25.493479 — immunology — Posted on 2022-05-25
785 Inference of Electrical Stimulation Sensitivity from Recorded Activity of Primate Retinal Ganglion Cells
Madugula, S. S.; Vilkhu, R. S.; Shah, N. P.; Grosberg, L. E.; Kling, A.; Goglietino, A. R.; Nguyen, H.; Hottowy, P.; Sher, A.; Litke, A. M.; Chichilnisky, E. J.
10.1101/2021.10.22.465478 — neuroscience — Posted on 2022-05-25
788 JBrowse Jupyter: A Python interface to JBrowse 2
Martinez, T. D. J.; Hershberg, E.; Guo, E.; Stevens, G. J.; Diesh, C.; Xie, P.; Bridge, C.; Cain, S.; Haw, R.; Buels, R. M.; Stein, L. D.; Holmes, I. H.
10.1101/2022.05.11.491552 — bioinformatics — Posted on 2022-05-25
795 Mass extravasation and tubular uptake of red blood cells results in toxic injury to the tubules during kidney ischemia from venous clamping
McLarnon, S. R.; Johnson, C.; Sun, J.; Wei, Q.; Csanyi, G.; O'Herron, P.; Marshall, B.; Sullivan, J. C.; Barrett, A.; O'Connor, P. M.
10.1101/2022.03.31.486613 — physiology — Posted on 2022-05-25
796 The heterogeneous distribution of extracellular adenosine reveals a myeloid-dependent axis, shaping the immunosuppressive microenvironment in pancreatic ductal adenocarcinoma
Graziano, V.; Dannhorn, A.; Hulme, H.; Williamson, K.; Buckley, H.; Lee, S. Y.; Kaistha, B. P.; Islam, S.; Thaventhiran, J. E. D.; Richards, F. M.; Goodwin, R.; Brais, R.; Dovedi, S. J.; Schuller, A. G.; Eyles, J.; Jodrell, D. I.
10.1101/2022.05.24.493238 — cancer biology — Posted on 2022-05-25
798 Design of a systemic small molecule clinical STING agonist using physics-based simulations and artificial intelligence
Allen, B. K.; Kulkarni, M.; Chamberlain, B.; Dwight, T.; Koh, C.; Samant, R.; Jernigan, F.; Rice, J.; Tan, D.; Li, S.; Marino, K.; Huang, H.; Chiswick, E.; Tesar, B.; Sparks, S.; Lin, Z.; McGee, T. D.; Kolossvary, I.; Lin, C.; Shechter, S.; Soutter, H.; Bastos, C.; Taimi, M.; Lai, S.; Petrin, A.; Kane, T.; Swann, S.; Gardner, H.; Winter, C.; Sherman, W.
10.1101/2022.05.23.493001 — cancer biology — Posted on 2022-05-25
800 An in silico genome-wide screen for circadian clock strength in human samples
Wu, G.; Ruben, M. D.; Francey, L. J.; Lee, Y.; Anafi, R. C.; Hogenesch, J. B.
10.1101/2022.05.10.491250 — bioinformatics — Posted on 2022-05-25
802 INSERT-seq enables high resolution mapping of genomically integrated DNA using nanopore sequencing
Ivancic, D.; Mir-Pedrol, J.; Jaraba-Wallace, J.; Rafel, N.; Sanchez-Mejias, A.; Guell, M.
10.1101/2022.05.25.493391 — genomics — Posted on 2022-05-25
803 ExplaiNN: interpretable and transparent neural networks for genomics
Novakovsky, G.; Fornes, O.; Saraswat, M.; Mostafavi, S.; Wasserman, W. W.
10.1101/2022.05.20.492818 — genomics — Posted on 2022-05-25
804 Overexpression screen of chromosome 21 genes reveals modulators of Sonic hedgehog signaling relevant to Down syndrome
Moyer, A. J.; Fernandez, F. X.; Li, Y.; Klinedinst, D. K.; Florea, L. D.; Kazuki, Y.; Oshimura, M.; Reeves, R. H.
10.1101/2022.05.19.492735 — genetics — Posted on 2022-05-25
809 EcoEvoApps: Interactive Apps for Theoretical Models in Ecology and Evolutionary Biology
McGuire, R. M.; Hayashi, K. T.; Yan, X.; Carita Vaz, M.; Cinoglu, D.; Cowen, M. C.; Martinez-Blancas, A.; Sullivan, L. L.; Vazquez-Morales, S.; Kandlikar, G. S.
10.1101/2021.06.18.449026 — ecology — Posted on 2022-05-25
810 California's forest carbon offsets buffer pool is severely undercapitalized
Badgley, G.; Chay, F.; Chegwidden, O. S.; Hamman, J. J.; Freeman, J.; Cullenward, D.
10.1101/2022.04.27.488938 — ecology — Posted on 2022-05-25
811 Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2
Zhang, J.-L.; Richetti, S.; Ramezani, T.; Welcker, D.; Luetke, S.; Pogoda, H.-M.; Hatzold, J.; Zaucke, F.; Keene, D. R.; Bloch, W.; Sengle, G.; Hammerschmidt, M.
10.1101/2021.11.24.469833 — developmental biology — Posted on 2022-05-25
814 Phosphoproteomic mapping reveals distinct signaling actions and activation of protein synthesis and muscle hypertrophy by Isthmin-1
Zhao, M.; Dannieskiold-Samsoee, N. B.; Ulicna, L.; Nguyen, Q.; Voilquin, L.; Lee, D. E.; White, J. P.; Jiang, Z.; Cuthbert, N.; Paramasivam, S.; Bielczyk-Maczynska, E.; Van Rechem, C.; Svensson, K. J.
10.1101/2022.05.19.492758 — cell biology — Posted on 2022-05-25
815 Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis
Baskaran, P.; Mihaylov, S. R.; Vinsland, E.; Shah, K.; Granat, L.; Ultanir, S. K.; Tee, A. R.; Murn, J.; Bateman, J. M.
10.1101/2022.04.08.487575 — cell biology — Posted on 2022-05-25
816 De novo lipogenesis fuels adipocyte autophagosome membrane dynamics
Rowland, L. A.; GUILHERME, A.; Henriques, F.; DiMarzio, C.; Wetoska, N.; Kelly, M.; Reddig, K.; Hendricks, G.; Pan, M.; Han, X.; Ilkayeva, O. R.; Newgard, C. B.; Czech, M. P.
10.1101/2022.05.25.493413 — molecular biology — Posted on 2022-05-25
818 Translation is a key determinant controlling the fate of cytoplasmic long non-coding RNAs
ANDJUS, S.; SZACHNOWSKI, U.; VOGT, N.; HATIN, I.; PAPADOPOULOS, C.; LOPES, A.; NAMY, O.; WERY, M.; MORILLON, A.
10.1101/2022.05.25.493276 — molecular biology — Posted on 2022-05-25
820 De novo mapping of the apicomplexan Ca2+-responsive proteome
Herneisen, A. L.; Li, Z.-H.; Chan, A. W.; Moreno, S. N.; Lourido, S.
10.1101/2022.05.25.493445 — microbiology — Posted on 2022-05-25
824 Visualizing and manipulating hyperstabilization of T cell microvilli contacts by engineered chimeric antigen receptors
Beppler, C.; Eichorst, J.; Marchuk, K.; Cai, E.; Castellanos, C. A.; Sriram, V.; Roybal, K. T.; Krummel, M. F.
10.1101/2021.08.18.456686 — immunology — Posted on 2022-05-25
827 The Wernicke conundrum revisited: evidence from connectome-based lesion-symptom mapping
Matchin, W.; den Ouden, D.-B.; Hickok, G.; Hillis, A. E.; Bonilha, L.; Fridriksson, J.
10.1101/2021.10.25.465746 — neuroscience — Posted on 2022-05-25
828 DeCalciOn: A hardware system for real-time decoding of in-vivo calcium imaging data
Chen, Z.; Blair, G. J.; Guo, C.; Zhou, J.; Izquierdo, A.; Golshani, P.; Cong, J.; Aharoni, D.; Blair, H. T.
10.1101/2022.01.31.478424 — neuroscience — Posted on 2022-05-25
829 Brain injury accelerates the onset of a reversible age-related microglial phenotype associated with hyperphagocytosis and inflammatory neurodegeneration
Ritzel, R. M.; Li, Y.; Jiao, Y.; Lei, Z.; Doran, S. J.; He, J.; Shahror, R. A.; Henry, R. J.; Liu, S.; Stoica, B. A.; Faden, A. I.; Szeto, G.; Loane, D. J.; Wu, J.
10.1101/2022.05.24.493292 — neuroscience — Posted on 2022-05-25
831 A missense mutation in zinc finger homeobox-3 (ZFHX3) impedes growth and alters metabolism and hypothalamic gene expression in mice.
Nolan, P. M.; Banks, G.; Bourbia, N.; Wilcox, A. G.; Bentley, L.; Moir, L.; Kent, L.; Hillier, R.; Wilson, D.; Barrett, P.; Dumbell, R.
10.1101/2022.05.25.493441 — physiology — Posted on 2022-05-25
832 Fibrosis resolution in the mouse liver: role of Mmp12 and potential role of Calpain 1/2
Sato, T.; Head, K. Z.; Li, J.; Dolin, C. E.; Wilkey, D.; Skirtich, N.; McCreary, D. D.; Liu, S.; Beier, J. I.; McEnaney, R. M.; Merchant, M. L.; Arteel, G. E.
10.1101/2022.02.15.480540 — pathology — Posted on 2022-05-25
833 SMAD4 suppresses colitis-associated carcinoma through inhibition of CCL20/CCR6-mediated inflammation
Hanna, D. N.; Marincola-Smith, P.; Novitskiy, S. V.; Washington, M. K.; Zi, J.; Weaver, C. J.; Hamaamen, J. A.; Lewis, K. B.; Zhu, J.; Yang, J.; Liu, Q.; Beauchamp, R. D.; Means, A. L.
10.1101/2022.05.25.492945 — cancer biology — Posted on 2022-05-25
836 Targeted hydrolysis of native potato protein: A novel route for obtaining hydrolysates with improved interfacial properties
Gregersen Echers, S.; Jafarpour, A.; Yesiltas, B.; Garcia-Moreno, P. J.; Greve-Poulsen, M.; Hansen, D.; Jacobsen, C.; Overgaard, M. T.; Hansen, E. B.
10.1101/2022.05.25.493405 — biochemistry — Posted on 2022-05-25
837 PH Domain-Mediated Autoinhibition and Oncogenic Activation of Akt
Bae, H.; Viennet, T.; Park, E.; Chu, N.; Salguero, A.; Eck, M. J.; Arthanari, H.; Cole, P. A.
10.1101/2022.05.25.493453 — biochemistry — Posted on 2022-05-25
842 A bacterial E2 enzyme regulates an antiviral cGAS through a peptide exchange-ligation-cleavage mechanism
Yan, Y.; Huang, F.; Yu, B.; Cheng, R.; Wu, H.; Lu, X.; Wang, X.; Xiao, J.; Wang, L.; Zhu, B.
10.1101/2022.05.25.493364 — microbiology — Posted on 2022-05-25
843 Phylogenomic diversity elucidates mechanistic insights into Lyme borreliae host association
Combs, M. A.; Marcinkiewicz, A. L.; Dupuis, A. P.; Davis, A. D.; Lederman, P.; Nowak, T. A.; Stout, J. L.; Strle, K.; Fingerle, V.; Margos, G.; Ciota, A. T.; Diuk-Wasser, M. A.; Kolokotronis, S.-O.; Lin, Y.-P.
10.1101/2022.05.25.493352 — microbiology — Posted on 2022-05-25
844 Genetic characterisation of the Theileria annulata cytochrome b locus and its impact on buparvaquone resistance in ruminants
Ali, Q.; Zahid, O.; Mhadhbi, M.; Jones, B.; Darghouth, M. A.; Raynes, G.; Afshan, K.; Birtles, R.; Sargison, N. D.; Betson, M.; Chaudhry, U.
10.1101/2022.05.25.493409 — microbiology — Posted on 2022-05-25
847 A Proximity Biotinylation Assay with a Host Protein Bait Reveals Multiple Factors Modulating Enterovirus Replication
Moghimi, S.; Viktorova, E.; Gabaglio, S.; Zimina, A.; Budnik, B.; Wynn, B. G.; Sztul, E.; Belov, G.
10.1101/2022.05.24.493328 — microbiology — Posted on 2022-05-25
849 Approaches to generating virtual patient cohorts with applications in oncology
Surendran, A.; Sauteur-Robitaille, J. L.; Kleimeier, D.; Gevertz, J. L.; Wilkie, K. P.; Jenner, A. L.; Craig, M.
10.1101/2022.05.24.493265 — cancer biology — Posted on 2022-05-25
850 Short tandem repeats bind transcription factors to tune eukaryotic gene expression
Horton, C. A.; Alexandari, A. M.; Hayes, M. G. B.; Marklund, E.; Schaepe, J. M.; Aditham, A. K.; Shah, N.; Shrikumar, A. A.; Afek, A.; Greenleaf, W. J.; Gordan, R.; Zeitlinger, J.; Kundaje, A.; Fordyce, P. M.
10.1101/2022.05.24.493321 — biophysics — Posted on 2022-05-25
852 Weakly supervised deep learning for human breast cancer-related optical biomarker discovery in label-free virtual histopathology
Shi, J.; Tu, H.; Park, J.; Marjanovic, M.; Higham, A. M.; Luckey, N. N.; Cradock, K. A.; Liu, Z. G.; Boppart, S. A.
10.1101/2022.05.24.493356 — bioinformatics — Posted on 2022-05-25
854 Coenzyme A binding sites induce proximal acylation across protein families
Carrico, C.; Cruz, A.; Walter, M.; Meyer, J. G.; Wehrfritz, C.; Shah, S.; Wei, L.; Schilling, B.; Verdin, E.
10.1101/2022.05.24.493335 — biochemistry — Posted on 2022-05-25
857 Transcriptional control of adipogenesis by PATZ1
Patel, S.; Sparman, N.; Sadeh, S.; Wang, J.; Whitelegge, J. P.; Fried, S. K.; Waki, H.; Villanueva, C. J.; Seldin, M. M.; Sakaguchi, S.; Ellmeier, W.; Tontonoz, P.; Rajbhandari, P.
10.1101/2022.05.24.493273 — molecular biology — Posted on 2022-05-25
858 Rapid Loss of CD4 T Cells by Pyroptosis During Acute SIV Infection in Rhesus Macaques
He, X.; Aid, M.; Ventura, J.; Borducchi, E.; Lifton, M. A.; Liu, J.; Barouch, D. H.
10.1101/2022.05.24.493358 — microbiology — Posted on 2022-05-25
860 The selection of antibiotic- and bacteriophage-resistant Pseudomonas aeruginosa is prevented by their combination
Ferran, A. A.; Lacroix, M. Z.; Gourbeyre, O.; Huesca, A.; Gaborieau, B.; Debarbieux, L.; Bousquet-Melou, A.
10.1101/2022.05.25.493369 — microbiology — Posted on 2022-05-25
862 CspZ FH-binding sites as epitopes promote antibody-mediated Lyme borreliae clearance
Chen, Y.-L.; Marcinkiewicz, A. L.; Nowak, T. A.; Kundu, R. T.; Liu, Z.; Strych, U.; Bottazzi, M.-E.; Chen, W.-H.; Lin, Y.-P.
10.1101/2022.05.24.493343 — immunology — Posted on 2022-05-25
863 Optogenetic control of the integrated stress response reveals proportional encoding and the stress memory landscape
Batjargal, T.; Zappa, F.; Grant, R. J.; Piscopio, R. A.; Chialastri, A.; Dey, S. S.; Acosta-Alvear, D.; Wilson, M. Z.
10.1101/2022.05.24.493309 — systems biology — Posted on 2022-05-25
866 Increasing computational protein design literacy through cohort-based learning for undergraduate students
Yang, E. C.; Divine, R.; Kang, C. S.; Chan, S.; Arenas, E.; Subol, Z.; Tinker, P.; Manninen, H.; Feichtenbiner, A.; Mustafa, T.; Hallowell, J.; Orr, I.; Haddox, H.; Koepnick, B.; O'Connor, J.; Haydon, I. C.; Herpoldt, K.-L.; Van Wormer, K.; Abell, C.; Baker, D.; Khmelinskaia, A.; King, N. P.
10.1101/2022.05.24.493341 — scientific communication and education — Posted on 2022-05-25
867 Celloscope: a probabilistic model for marker-gene-driven cell type deconvolution in spatial transcriptomics data
Geras, A.; Darvish Shafighi, S.; Domzał, K.; Filipiuk, I.; Raczkowski, Łukasz; Toosi, H.; Kaczmarek, L.; Koperski, Łukasz; Lagergren, J.; Nowis, D.; Szczurek, E.
10.1101/2022.05.24.493193 — bioinformatics — Posted on 2022-05-25
870 Harnessing insect olfactory neural circuits for noninvasive detection of human cancer
Farnum, A.; Parnas, M.; Apu, E. H.; Cox, E.; Lefevre, N.; Contag, C. H.; Saha, D.
10.1101/2022.05.24.493311 — bioengineering — Posted on 2022-05-25
871 Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq
Akbari, V.; Hanlon, V. C. T.; O'Neill, K.; Lefebvre, L.; Schrader, K. A.; Lansdorp, P. M.; Jones, S. J. M.
10.1101/2022.05.24.493320 — genomics — Posted on 2022-05-25
872 Deletion mapping of regulatory elements for GATA3 reveals a distal T helper 2 cell enhancer involved in allergic diseases
Chen, H. V.; Fiaux, P. C.; Sen, A.; Luthra, I.; Ho, A. J.; Chen, A. R.; Guruvayurappan, K.; Lorenzini, M. H.; O'Connor, C.; McVicker, G.
10.1101/2022.05.24.493112 — genomics — Posted on 2022-05-25
874 Open science resources from the Tara Pacific expedition across coral reef and surface ocean ecosystems
lombard, f.; Bourdin, G.; Pesant, S.; Agostini, S.; Baudena, A.; Boissin, E.; Cassar, N.; Clampitt, M.; Conan, P.; da Silva, O.; Dimier, C.; Douville, E.; Elineau, A.; Fin, J.; Flores, J. M.; Ghiglione, J. F.; Hume, B. C. C.; Jalabert, L.; John, S. G.; Kelly, R. L.; Koren, I.; Lin, Y.; Marie, D.; McMinds, R.; Meriguet, Z.; Metzl, N.; Paz Garciax, D. A.; Pedrotti, M. L.; Poulain, J.; Pujo Pay, M.; Ras, J.; Reverdin, G.; Romac, S.; Rouan, A.; Rottinger, E.; Vardi, A.; Voolstra, C. R.; Moulin, C.; Iwankow, G.; Banaigs, B.; Bowler, C.; Forcioli, D.; Furla, P.; Galand, P. E.; Gilson, E.; Reynaud, S
10.1101/2022.05.25.493210 — ecology — Posted on 2022-05-25
875 Synechococcus nitrogen gene loss in iron-limited ocean regions
Sharpe, G. C.; Meyer, M. G.; Gong, W.; Burns, S. M.; Tagliabue, A.; Buck, K. N.; Santoro, A. E.; Graff, J. R.; Marchetti, A.; Gifford, S. M.
10.1101/2022.05.24.493279 — ecology — Posted on 2022-05-25
878 Mycobacterium tuberculosis genetic features associated with pulmonary tuberculosis severity
Genestet, C.; Refregier, G.; Hodille, E.; Zein-Eddine, R.; Le Meur, A.; Hak, F.; Barbry, A.; Westeel, E.; Berland, J.-L.; Engelmann, A.; Verdier, I.; Lina, G.; Ader, F.; Dray, S.; Jacob, L.; Massol, F.; Venner, S.; Dumitrescu, O.
10.1101/2022.05.25.493361 — microbiology — Posted on 2022-05-25
879 Genomic surveillance of carbapenem-resistant Klebsiella in Wales reveals persistent spread of K. pneumoniae ST307 and adaptive evolution of pOXA-48-like plasmids
David, S.; Mentasti, M.; Sands, K.; Portal, E.; Graham, L.; Watkins, J.; Williams, C.; Healy, B.; Spiller, O. B.; Aanensen, D.; Wootton, M. B.; Jones, L. S.
10.1101/2022.05.25.492139 — microbiology — Posted on 2022-05-25
880 Adaptation of cyanobacteria to the endolithic light spectrum in hyper-arid deserts
Murray, B.; Ertekin, E.; Dailey, M.; Soulier, N. T.; Shen, G.; Bryant, D. A.; Perez-Fernandez, C.; DiRuggiero, J.
10.1101/2022.05.24.493334 — microbiology — Posted on 2022-05-25
881 A preprocessing and functional connectivity analysis pipeline for mesoscale calcium imaging
O'Connor, D.; Mandino, F.; Shen, X.; Horien, C.; Ge, X.; Herman, P.; Crair, M.; Papademetris, X.; Lake, E. M.; Constable, R. T.
10.1101/2022.05.24.493310 — neuroscience — Posted on 2022-05-25
885 A very long chain fatty acid responsive transcription factor, MYB93, regulates lateral root development in Arabidopsis
Uemura, Y.; Kimura, S.; Ohta, T.; Suzuki, T.; Mase, K.; Kato, H.; Sakaoka, S.; Komine, Y.; Hotta, K.; Shimizu, M.; Morikami, A.; Tsukagoshi, H.
10.1101/2022.05.24.493307 — plant biology — Posted on 2022-05-25
888 Gut Microbes and the Liver Circadian Clock Partition Glucose and Lipid Metabolism
Frazier, K.; Manzoor, S.; Carroll, K.; DeLeon, O.; Miyoshi, S.; Miyoshi, J.; St George, M.; Tan, A.; Izumo, M.; Takahashi, J. S.; Rao, M. C.; Leone, V. A.; Chang, E. B.
10.1101/2022.05.24.491361 — physiology — Posted on 2022-05-25
889 Coiling of cellular protrusions around extracellular fibers
Sadhu, R. K.; Hernandez-Padilla, C.; Eisenbach, Y. E.; Zhang, L.; Vishwasrao, H. D.; Behkam, B.; Shroff, H.; Igliv{c}, A.; Peles, E.; Nain, A.; Gov, N.
10.1101/2022.05.24.493192 — biophysics — Posted on 2022-05-25
890 Subcutaneous delivery of an antibody against SARS-CoV-2 from a supramolecular hydrogel depot
Kasse, C. M.; Yu, A. C.; Powell, A. E.; Roth, G. A.; Liong, C. S.; Jons, C. K.; Buahin, A.; Maikawa, C. L.; Youssef, S.; Glanville, J. E.; Appel, E. A.
10.1101/2022.05.24.493347 — bioengineering — Posted on 2022-05-25
892 ReSurveyGermany: Vegetation-plot time-series over the past hundred years in Germany
Jandt, U.; Bruelheide, H.; Berg, C.; Bernhardt-Roemermann, M.; Blueml, V.; Bode, F.; Dengler, J.; Diekmann, M.; Dierschke, H.; Doerfler, I.; Doering, U.; Dullinger, S.; Haerdtle, W.; Haider, S.; Heinken, T.; Horchler, P.; Jansen, F.; Kudernatsch, T.; Kuhn, G.; Lindner, M.; Matesanz, S.; Metze, K.; Meyer, S.; Mueller, F.; Mueller, N.; Naaf, T.; Peppler-Lisbach, C.; Poschlod, P.; Roscher, C.; Rosenthal, G.; Rumpf, S. B.; Schmidt, W.; Schrautzer, J.; Schwabe, A.; Schwartze, P.; Sperle, T.; Stanik, N.; Stroh, H.-G.; Storm, C.; Voigt, W.; von Hessberg, A.; von Oheimb, G.; Wagner, E.-R.; Wegener, U.
10.1101/2022.05.25.493323 — ecology — Posted on 2022-05-25
893 Distinct antigenic properties of the SARS-CoV-2 Omicron lineages BA.4 and BA.5
Willett, B. J.; Kurshan, A.; Thakur, N.; Newman, J.; Manali, M.; Tyson, G.; Logan, N.; Murcia, P. R.; Snell, L. B.; Edgeworth, J. D.; Zhou, J.; Sukhova, K.; Amirthalingam, G.; Brown, K.; Charleston, B.; Malim, M. H.; Thomson, E. C.; Barclay, W. S.; Bailey, D.; Doores, K. J.; Peacock, T. P.
10.1101/2022.05.25.493397 — microbiology — Posted on 2022-05-25
894 Intranasal vaccination induced cross-protective secretory IgA antibodies against SARS-CoV-2 variants with reducing the potential risk of lung eosinophilic immunopathology
Hemmi, T.; Ainai, A.; Hashiguchi, T.; Tobiume, M.; Kanno, T.; Iwata-Yoshikawa, N.; Iida, S.; Sato, Y.; Miyamoto, S.; Ueno, A.; Sano, K.; Saito, S.; Shiwa-Sudo, N.; Nagata, N.; Tamura, K.; Suzuki, R.; Hasegawa, H.; Suzuki, T.
10.1101/2022.05.24.493348 — microbiology — Posted on 2022-05-25
895 Multimodal cues displayed by submissive rats promote prosocial choices by dominants
Gachomba, M. J. M.; Esteve-Agraz, J.; Caref, K.; Maroto, A. S.; Bortolozzo-Gleich, H.; Laplagne, D. A.; Marquez, C.
10.1101/2022.01.12.475866 — neuroscience — Posted on 2022-05-25
896 Hemin shows antiviral activity in vitro, possibly through suppression of viral entry mediators.
UNAL, M. A.; BITIRIM, C. V.; SOMERS, J.; SUMMAK, G. Y.; BUL BESBINAR, O.; KOCAKAYA, E.; GURCAN, C.; NAZIR, H.; Aksoy Ozer, Z. B.; OZKAN, S. A.; BEREKETOGLU, S.; OZKUL, A.; DEMIR, E.; AKCALI, K. C.; YILMAZER, A.
10.1101/2022.05.24.493187 — pharmacology and toxicology — Posted on 2022-05-25
897 Cell walls are dynamically O-acetylated in the green seaweed, Ulva compressa
Bothwell, J. H.; Goodridge, A.; Rapin, M.; Brennan, P. J.; Traslavina Lopez, A.; Agrawal, A.; Fry, S. C.; Campbell, G.; Blomme, J.
10.1101/2022.05.24.493306 — cell biology — Posted on 2022-05-25
898 Penicillin Binding Protein Substitutions Co-occur with Fluoroquinolone Resistance in 'Epidemic Lineages of Multi Drug-Resistant Clostridioides difficile
Dingle, K. E.; Freeman, J.; Didelot, X.; Eyre, D. W.; Swann, J.; Spittal, W.; Clark, E. V.; Jolley, K. A.; Walker, A. S.; Wilcox, M. H.; Crook, D. W.
10.1101/2022.05.23.493179 — microbiology — Posted on 2022-05-25
899 Input-Specific Inhibitory Plasticity Improves Decision Accuracy Under Noise
Song, S.; Shen, B.; Machold, R.; Rudy, B.; Glimcher, P. W.; Louie, K.; Froemke, R.
10.1101/2022.05.24.493332 — neuroscience — Posted on 2022-05-25
901 A humanized yeast model reveals dominant-negative properties of neuropathy-associated alanyl-tRNA synthetase mutations
Meyer-Schuman, R.; Marte, S.; Smith, T.; Feely, S. M. E.; Kennerson, M.; Nicholson, G.; Shy, M. E.; Koutmou, K.; Antonellis, A.
10.1101/2022.05.25.493316 — genetics — Posted on 2022-05-25
902 Endothelial Brg1 fine-tunes Notch signaling during zebrafish heart regeneration
Xiao, C.; Hou, J.; Wang, F.; Song, Y.; Zheng, J.; Luo, L.; Wang, J.; Ding, W.; Zhu, X.; Xiong, J.-W.
10.1101/2022.05.18.492445 — developmental biology — Posted on 2022-05-25
903 Phosphoproteomic mapping reveals distinct signaling actions and activation of protein synthesis and muscle hypertrophy by Isthmin-1
Zhao, M.; Banhos Dannieskiold-Samsoe, N.; Ulicna, L.; Nguyen, Q.; Voilquin, L.; Lee, D. E.; White, J. P.; Jiang, Z.; Cuthbert, N.; Paramasivam, S.; Bielczyk-Maczynska, E.; Van Rechem, C.; Svensson, K. J.
10.1101/2022.05.19.492758 — cell biology — Posted on 2022-05-25
904 TDP-43 oligomerization and RNA binding are codependent but their loss elicits distinct pathologies
Perez-Berlanga, M.; Wiersma, V. I.; Zbinden, A.; De Vos, L.; Wagner, U.; Foglieni, C.; Mallona, I.; Betz, K. M.; Clery, A.; Weber, J.; Guo, Z.; Rigort, R.; de Rossi, P.; Manglunia, R.; Tantardini, E.; Sahadevan, S.; Stach, O.; Hruska-Plochan, M.; Allain, F. H.- T.; Paganetti, P.; Polymenidou, M.
10.1101/2022.05.23.493029 — cell biology — Posted on 2022-05-25
907 Isolation and Characterization of Sympathetic Extracellular Vesicles
Mason, A. J.; Keeler, A. B.; Kabir, F.; Winckler, B.; Deppmann, C. D.
10.1101/2022.05.24.493096 — neuroscience — Posted on 2022-05-25
909 Peripheral membrane proteins modulate stress tolerance by safeguarding cellulose synthases
Kesten, C.; Garcia-Moreno, A.; Amorim-Silva, V.; Menna, A.; Castillo, A. G.; Percio, F.; Armengot, L.; Ruiz-Lopez, N.; Jaillais, Y.; Sanchez-Rodriguez, C.; Botella, M. A.
10.1101/2022.05.24.493199 — plant biology — Posted on 2022-05-25
911 The Balance between Saturated and Unsaturated Fatty Acids Regulates Ovarian Cancer Cell Fate
Zhao, G.; Tan, Y.; Cardenas, H.; Vayngart, D.; Huang, H.; Wang, Y.; Keathley, R.; Wei, J.-J.; Ferreira, C. R.; Cheng, J.-X.; Matei, D.
10.1101/2022.05.24.493247 — cancer biology — Posted on 2022-05-25
916 Sustained pigmentation causes DNA damage and invokes translesion polymerase Pol κ for repair in melanocytes
Natarajan, V.; Khanna, S.; Ghazi, M.; Subramaniam, Y. J.; Gupta, I.; Sultan, F.; Sharma, K.; Chandna, S.; Gokhale, R. S.
10.1101/2022.05.20.492761 — cell biology — Posted on 2022-05-25
920 Impact of Shelterin Complex on Telomere Accessibility
Shiekh, S.; Jack, A.; Mustafa, G.; Kodikara, S. G.; Gyawali, P.; Hoque, M. E.; Yildiz, A.; Balci, H.
10.1101/2022.05.24.493289 — biophysics — Posted on 2022-05-25
923 Impact of bioactive molecule inclusion in lyophilized silk scaffolds varies between in vivo and in vitro assessments
Jameson, J. F.; Pacheco, M. O.; Bender, E. C.; Kotta, N. M.; Black, L. D.; Kaplan, D. L.; Grasman, J. M.; Stoppel, W. L.
10.1101/2022.05.24.493207 — bioengineering — Posted on 2022-05-25
924 Human skeletal muscle ageing atlas
Kedlian, V. R.; Wang, Y.; Liu, T.; Chen, X.; Bolt, L.; Shen, Z.; Fasouli, E. S.; Prigmore, E.; Kleshchevnikov, V.; Li, T.; Lawrence, J. E.; Huang, N.; Guo, Q.; Yang, L.; Polanski, K.; Dabrowska, M.; Tudor, C.; Li, X.; Bayraktar, O. A.; Patel, M.; Meyer, K. B.; Kumasaka, N.; Mahbubani, K. T.; Xiang, A. P.; Saeb-Parsy, K.; Teichmann, S. A.; Zhang, H.
10.1101/2022.05.24.493094 — genomics — Posted on 2022-05-25
930 An individualized fMRI protocol to assess semantic congruency effects on episodic memory in an ageing multilingual population
Perquin, M.; Viswanathan, S.; Vaillant, M.; Risius, O.; Huiart, L.; Schmit, J.-C.; Diederich, N. J.; Fink, G. R.; Kukolja, J.
10.1101/2021.09.07.459272 — neuroscience — Posted on 2022-05-25
934 The heterogeneous distribution of extracellular adenosine reveals a myeloid-dependent axis, shaping the immunosuppressive microenvironment in pancreatic ductal adenocarcinoma
Graziano, V.; Dannhorn, A.; Hulme, H.; Williamson, K.; Buckley, H.; Lee, S. Y.; Kaistha, B. P.; Islam, S.; Thaventhiran, J. E. D.; Richards, F. M.; Goodwin, R.; Brais, R.; Dovedi, S. J.; Schuller, A. G.; Eyles, J.; Jodrell, D. I.
10.1101/2022.05.24.493238 — cancer biology — Posted on 2022-05-25
935 Single-Cell RNA Sequencing Reveals the Effects of Chemotherapy on Human Pancreatic Adenocarcinoma and its Tumor Microenvironment
Werba, G.; Weissinger, D.; Kawaler, E. A.; Zhao, E.; Kalfakakou, D.; Dhara, S.; Oh, G.; Jing, X.; Beri, N.; Khanna, L.; Gonda, T.; Oberstein, P.; Hajdu, C.; Loomis, C. A.; Heguy, A.; Sherman, M. H.; Lund, A. W.; Welling, T. H.; Dolgalev, I.; Tsirigos, A.; Simeone, D. M.
10.1101/2022.05.24.493132 — cancer biology — Posted on 2022-05-25
937 Microparticle-delivered Cxcl9 delays the relapse of Braf inhibitor-treated melanoma
Romano, G.; Paradiso, F.; Miller, J. P.; Liang, R. J.; Wargo, J. A.; Taraballi, F.; Costello, J. C.; Kwong, L. N.
10.1101/2022.05.24.493271 — cancer biology — Posted on 2022-05-25
938 PKC-alpha regulates the phosphorylation of KRAS that suppresses its oncogenic properties
Joglekar, T.; Ku, A.; Schollaert, E.; Gong, Y.-N.; Stewart-Ornstein, J.; Urisman, A.; Wang, M.-T.
10.1101/2022.05.24.493257 — cancer biology — Posted on 2022-05-25
939 SMALL MOLECULE ACTIVATORS OF B56-PP2A RESTORE 4E-BP EXPRESSION AND FUNCTION TO SUPPRESS CAP-DEPENDENT TRANSLATION IN CANCER CELLS
Lum, M. A.; Jonas-Breckenridge, K. A.; Black, A. R.; Woods, N. T.; O'Connor, C. M.; Avelar, R. A.; DiFeo, A.; Narla, G.; Black, J. D.
10.1101/2022.05.24.493272 — cancer biology — Posted on 2022-05-25
940 Design of a systemic small molecule clinical STING agonist using physics-based simulations and artificial intelligence
Allen, B. K.; Kulkarni, M.; Chamberlain, B.; Dwight, T.; Koh, C.; Samant, R.; Jernigan, F.; Rice, J.; Tan, D.; Li, S.; Marino, K.; Huang, H.; Chiswick, E.; Tesar, B.; Sparks, S.; Lin, Z.; McGee, T. D.; Kolossvary, I.; Lin, C.; Shechter, S.; Soutter, H.; Bastos, C.; Taimi, M.; Lai, S.; Petrin, A.; Kane, T.; Swann, S.; Gardner, H.; Winter, C.; Sherman, W.
10.1101/2022.05.23.493001 — cancer biology — Posted on 2022-05-25
941 The structure of yeast Npl3 bound to RNA reveals a cooperative sequence-specific recognition and an RNA chaperone role in splicing
Moursy, A.; Clery, A.; Gerhardy, S.; Betz, K. M.; Rao, S.; Campagne, S.; Beusch, I.; Duszczyk, M. M.; Robinson, M. D.; Panse, V. G.; Allain, F. H.- T.
10.1101/2022.05.24.493251 — biophysics — Posted on 2022-05-25
948 Single-cell profiling identifies a spectrum of human unconventional intraepithelial T lineage cells
Billiet, L.; De Cock, L.; Sanchez Sanchez, G.; Mayer, R. L.; Goetgeluk, G.; De Munter, S.; Pille, M.; Ingels, J.; Jansen, H.; Weening, K.; Pascal, E.; Raes, K.; Bonte, S.; Kerre, T.; Vandamme, N.; Seurinck, R.; Roels, J.; Lavaert, M.; Van Nieuwerburgh, F.; Leclercq, G.; Taghon, T.; Impens, F.; Menten, B.; Vermijlen, D.; Vandekerckhove, B.
10.1101/2022.05.24.492634 — immunology — Posted on 2022-05-25
949 Neural signatures of auditory hypersensitivity following acoustic trauma
McGill, M.; Hight, A. E.; Watanabe, Y.; Parthasarathy, A.; Cai, D.; Clayton, K.; Hancock, K. E.; Takesian, A.; Kujawa, S.; Polley, D. B.
10.1101/2022.05.24.493204 — neuroscience — Posted on 2022-05-25
951 Induction of Anxiety-Like Phenotypes by Knockout of Cannabinoid Type-1 Receptor in Amygdala of Marmosets
Zheng, D.; Zhu, L.; Li, R.; Shen, C.-J.; Cai, R.; Sun, H.; Wang, X.; Ding, Y.; Xu, B.; Jia, G.; Li, X.; Gao, L.; Li, X.-M.
10.1101/2022.05.24.493231 — neuroscience — Posted on 2022-05-25
952 Bimodal pilot study on inner speech decoding reveals the potential of combining EEG and fMRI
Simistira Liwicki, F.; Gupta, V.; Saini, R.; De, K.; Abid, N.; Rakesh, S.; Wellington, S.; Wilson, H.; Liwicki, M.; Eriksson, J.
10.1101/2022.05.24.492109 — neuroscience — Posted on 2022-05-25
954 Striatal Mu-Opioid Receptor Activation Triggers Direct-Pathway GABAergic Plasticity to Induce Negative Affect
Wang, W.; Xie, X.; Zhuang, X.; Huang, Y.; Tan, T.; Gangal, H.; Huang, Z.; Purvines, W.; Wang, X.; Stefanov, A.; Chen, R.; Yu, E.; Hook, M.; Huang, Y.; Darcq, E.; Wang, J.
10.1101/2022.05.23.493082 — neuroscience — Posted on 2022-05-25
955 Bi-phasic patterns of age-related differences in dopamine D1 receptors across the adult lifespan
Johansson, J.; Nordin, K.; Pedersen, R.; Karalija, N.; Papenberg, G.; Andersson, M.; Korkki, S. M.; Riklund, K.; Guitart-Masip, M.; Rieckmann, A.; Bäckman, L.; Nyberg, L.; Salami, A.
10.1101/2022.05.24.493225 — neuroscience — Posted on 2022-05-25
956 High-fidelity restoration of visual signals by electrical stimulation in the central primate retina
Gogliettino, A. R.; Madugula, S. S.; Grosberg, L. E.; Vilkhu, R. S.; Brown, J.; Nguyen, H.; Kling, A.; Hottowy, P.; Dabrowski, W.; Sher, A.; Litke, A. M.; Chichilnisky, E. J.
10.1101/2022.05.24.493162 — neuroscience — Posted on 2022-05-25
957 Anterior insular cortex firing links initial and sustained encoding during aversion-resistant alcohol consumption
Starski, P. A.; Morningstar, M. D.; Katner, S.; Frasier, R.; De Oliveira Sergio, T.; Wean, S.; Lapish, C.; Hopf, F.
10.1101/2022.05.24.493243 — neuroscience — Posted on 2022-05-25
967 Robust and Versatile Arrayed Libraries for Human Genome-Wide CRISPR Activation, Deletion and Silencing
Yin, J.-A.; Frick, L.; Scheidmann, M. C.; Trevisan, C.; Dhingra, A.; Spinelli, A.; Wu, Y.; Yao, L.; Vena, D. L.; De Cecco, E.; Ging, K.; Liu, T.; Tager, J.; Rodriguez, S.; Guo, J.; Berry, S.; Losa, M.; Hornemann, S.; Kampmann, M.; Pelkmans, L.; Hoepfner, D.; Heutink, P.; Aguzzi, A.
10.1101/2022.05.25.493370 — genomics — Posted on 2022-05-25
969 Sexual coercion in a natural mandrill population
Smit, N.; Baniel, A.; Roura-Torres, B.; Amblard-Rambert, P.; Charpentier, M. J. E.; Huchard, E.
10.1101/2022.02.07.479393 — ecology — Posted on 2022-05-25
972 Lineage-Specific Differences and Regulatory Networks Governing Human Chondrocyte Development
Richard, D.; Pregizer, S.; Venkatasubramanian, D.; Muthuirulan, P.; Liu, Z.; Capellini, T. D.; Craft, A. M.
10.1101/2022.05.25.493388 — developmental biology — Posted on 2022-05-25
973 ORP5/8 AND MIB/MICOS LINK ER-MITOCHONDRIA AND INTRAMITOCHONDRIAL CONTACTS FOR NON-VESICULAR TRANSPORT OF PHOSPHATIDYLSERINE
Monteiro-Cardoso, V. F.; Rochin, L.; Arora, A.; Houcine, A.; Jaaskelainen, E.; Kivela, A. M.; Sauvanet, C.; Le Bars, R.; Marien, E.; Dehairs, J.; Neveu, J.; El Khallouki, N.; Santonico, E.; Swinnen, J. V.; Tareste, D.; Olkkonen, V. M.; Giordano, F.
10.1101/695577 — cell biology — Posted on 2022-05-25
974 Sickle red blood cell derived extracellular vesicles activate endothelial cells and enhance sickle red cell adhesion mediated by von Willebrand factor
An, R.; Man, Y.; Cheng, K.; Zhang, T.; Chen, C.; Kucukal, E.; Wulftange, W.; Goreke, U.; Bode, A.; Nayak, L.; Vercellotti, G. M.; Belcher, J. D.; Little, J. A.; Gurkan, U. A.
10.1101/2022.05.25.492883 — cell biology — Posted on 2022-05-25
977 Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies
Ko, K.-T.; Lennartz, F.; Mekhaiel, D.; Guloglu, B.; Marini, A.; Deuker, D.; Long, C.; Jore, M.; Miura, K.; Biswas, S.; Higgins, M. K.
10.1101/2022.05.24.493318 — microbiology — Posted on 2022-05-25
978 Accurate angular integration with only a handful of neurons
Noorman, M.; Hulse, B. K.; Jayaraman, V.; Romani, S.; Hermundstad, A. M.
10.1101/2022.05.23.493052 — neuroscience — Posted on 2022-05-25
979 Reward enhances memory via age-varying online and offline neural mechanisms across development
Cohen, A. O.; Glover, M. M.; Shen, X.; Phaneuf, C. V.; Avallone, K. N.; Davachi, L.; Hartley, C. A.
10.1101/2021.09.14.460286 — neuroscience — Posted on 2022-05-25
980 Episodic memory formation in naturalistic viewing
Nikolaev, A. R.; Bramao, I.; Johansson, R.; Johansson, M.
10.1101/2022.05.24.485821 — neuroscience — Posted on 2022-05-25
981 A miR-124-mediated post-transcriptional mechanism controlling the cell fate switch of astrocytes to induced-neurons
Papadimitriou, E.; Koutsoudaki, P. N.; Thanou, I.; Karamitros, T.; Karagkouni, D.; Chroni-Tzartou, D.; Gaitanou, M.; Gkemisis, C.; Margariti, M.; Xingi, E.; Tzartos, S. J.; Hatzigeorgiou, A. G.; Thomaidou, D.
10.1101/2020.06.01.127126 — neuroscience — Posted on 2022-05-25
989 Haplotype-phrased and chromosome-level assembly of Puccinia polysora, a giga-scale fungal pathogen causing southern corn rust
Liang, j.; Li, y.; Dodds, P. N.; Figueroa, M.; Sperschneider, J.; Han, S.; Tsui, C. K. M.; Zhang, K.; Li, L.; Ma, Z.; Cai, L.
10.1101/2022.05.18.492400 — genomics — Posted on 2022-05-25
994 The evolutionary conserved complex CEP90, FOPNL and OFD1 specifies the future location of centriolar distal appendages, and promotes their assembly
Le Borgne, P.; Greibill, L.; Laporte, M. H.; Lemullois, M.; Bouhouche, K.; Temagoult, M.; Rosnet, O.; Le Guennec, M.; Lignieres, L.; Chevreux, G.; Koll, F.; Hamel, V.; Guichard, P.; Tassin, A.-M.
10.1101/2021.07.13.452210 — cell biology — Posted on 2022-05-25
995 Morphological profiling by high-throughput single-cell biophysical fractometry
Zhang, Z.; Lee, K. C. M.; Siu, D. M. D.; Lai, Q. T. K.; Lam, E. Y.; Tsia, K. K.
10.1101/2022.05.24.493226 — cell biology — Posted on 2022-05-25
996 Multimodal cues displayed by submissive rats promote prosocial choices by dominants
Gachomba, M. J. M.; Esteve-Agraz, J.; Caref, K.; Maroto, A. S.; Bortolozzo-Gleich, H.; Laplagne, D. A.; Marquez, C.
10.1101/2022.01.12.475866 — neuroscience — Posted on 2022-05-25
998 A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding
Wang, L.; Park, J. Y.; Liu, F.; Olesen, K.; Hou, S.; Peng, J. C.; Infield, J.; Levesque, A. C.; Wang, Y.-D.; Jin, H.; Fan, Y.; Connelly, J. P.; Pruett-Miller, S. M.; Hu, M. G.; Hinds, P. W.; Han, Y.-G.
10.1101/2022.05.24.493266 — neuroscience — Posted on 2022-05-25
1002 Fitm2 is required for ER homeostasis and normal function of murine liver
Bond, L. M.; Ibrahim, A.; Lai, Z. W.; Walzem, R. L.; Bronson, R.; Ilkayeva, O.; Walther, T. C.; Farese, R.
10.1101/2022.05.24.493342 — cell biology — Posted on 2022-05-25
1003 Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding
Alghamdi, T. A.; Krentz, N. A. J.; Smith, N.; Spigelman, A. F.; Rajesh, V.; Jha, A.; Ferdaoussi, M.; Manning Fox, J. E.; Sun, H.; Sun, Z.; Gloyn, A. L.; MacDonald, P. E.
10.1101/2022.05.18.492530 — physiology — Posted on 2022-05-24
1006 Par3/Bazooka promotes Notch pathway target gene activation
Wu, J.; Bala Tannan, N.; Vuong, L. T.; Koca, Y.; Collu, G. M.; Mlodzik, M.
10.1101/2022.05.24.493322 — developmental biology — Posted on 2022-05-24
1009 Highly-multiplexed serology for non-human mammals
Schuettenberg, A.; Pina, A.; Metrailer, M.; Pelaez-Sanchez, R. G.; Agudeloa-Florez, P.; Alvaro Lopez, J.; Ryle, L.; Monroy, F.; Altin, J.; Ladner, J.
10.1101/2022.05.24.493290 — immunology — Posted on 2022-05-24
1013 The LEGO theory of the developing functional connectome
Busch, E. L.; Rapuano, K. M.; Anderson, K. M.; Rosenberg, M. D.; Watts, R.; Casey, B.; Haxby, J. V.; Feilong, M.
10.1101/2022.05.24.493295 — neuroscience — Posted on 2022-05-24
1016 Inference of Electrical Stimulation Sensitivity from Recorded Activity of Primate Retinal Ganglion Cells
Madugula, S. S.; Vilkhu, R. S.; Shah, N. P.; Grosberg, L. E.; Kling, A.; Goglietino, A. R.; Nguyen, H.; Hottowy, P.; Sher, A.; Litke, A. M.; Chichilnisky, E. J.
10.1101/2021.10.22.465478 — neuroscience — Posted on 2022-05-24
1018 Loss-of-function mutation in human Oxidation Resistance gene 1 disrupts the spatial-temporal regulation of histone arginine methylation in early brain development
Lin, X.; Wang, W.; Yang, M.; Damseh, N.; Sousa, M. M. L. d.; Jacob, F.; Lang, A.; Kristiansen, E.; Pannone, M.; Kissova, M.; Almaas, R.; Kusnierczyk, A.; Siller, R.; Shahrour, M.; Al-Ashhab, M.; Abu-Libdeh, B.; Tang, W.; Slupphaug, G.; Elpeleg, O.; Boe, S. O.; Eide, L.; Sullivan, G. J.; Rinholm, J. E.; Song, H.; Ming, G.-L.; Van Loon, B.; Edvardson, S.; Ye, J.; Bjoras, M.
10.1101/2022.05.24.493324 — pathology — Posted on 2022-05-24
1019 Emerging Accessibility Patterns in Long Telomeric Overhangs
Shiekh, S.; Mustafa, G.; Kodikara, S. G.; Hoque, M. E.; Yokie, E.; Portman, J. J.; Balci, H.
10.1101/2021.11.24.469879 — biophysics — Posted on 2022-05-24
1020 Identifying interactions in omics data for clinical biomarker discovery using symbolic regression
Christensen, N. J.; Demharter, S.; Machado, M.; Pedersen, L.; Salvatore, M.; Stentoft-Hansen, V.; Triana Iglesias, M.
10.1101/2022.01.14.475226 — bioinformatics — Posted on 2022-05-24
1023 Caveats to deep learning approaches to RNA secondary structure prediction
Flamm, C.; Wielach, J.; Wolfinger, M. T.; Badelt, S.; Lorenz, R.; Hofacker, I.
10.1101/2021.12.14.472648 — bioinformatics — Posted on 2022-05-24
1025 Evolution and Diversification Dynamics of Butterflies
Kawahara, A. Y.; Storer, C.; Carvalho, A. P. S.; Plotkin, D. M.; Condamine, F.; Braga, M. P.; Ellis, E. A.; St Laurent, R. A.; Li, X.; Barve, V.; Cai, L.; Earl, C.; Frandsen, P. B.; Owens, H. L.; Valencia-Montoya, W. A.; Aduse-Poku, K.; Toussaint, E. F. A.; Dexter, K. M.; Doleck, T.; Markee, A.; Messcher, R.; Nguyen, Y.-L.; Badon, J. A. T.; Benitez, H. A.; Braby, M. F.; Buenavente, P. A. C.; Chan, W.-P.; Collins, S. C.; Childers, R. A. R.; Dankowicz, E.; Eastwood, R.; Fric, Z. F.; Gott, R.; Hall, J. P. W.; Hallwachs, W.; Hardy, N. B.; Sipe, R. L. H.; Heath, A.; Hinolan, J. D.; Homziak, N. T.;
10.1101/2022.05.17.491528 — evolutionary biology — Posted on 2022-05-24
1029 The representation of priors and decisions in parietal cortex
Marshall, T. R.; Ruesseler, M.; Hunt, L. T.; O'Reilly, J. X.
10.1101/2021.05.03.442155 — neuroscience — Posted on 2022-05-24
1031 PGC-1β and ERRα promote glutamine metabolism and colorectal cancer survival via transcriptional regulation of PCK2
Frodyma, D. E.; Troia, T. C.; Berg, J. A.; Rao, C.; Svoboda, R. A.; Shinde, D. D.; Thomas, V. C.; Lewis, R. E.; Fisher, K. W.
10.1101/2022.05.20.492006 — cancer biology — Posted on 2022-05-24
1035 Targeting Pulmonary Fibrosis by SLC1A5 dependent Glutamine Transport Blockade
Choudhury, M.; Schaefbauer, K. J.; Kottom, T. J.; Yi, E. S.; Tschumperlin, D. J.; Limper, A. H.
10.1101/2022.05.23.493168 — molecular biology — Posted on 2022-05-24
1036 Gram-positive bacteria evade phage predation through endolysin-mediated L-form conversion
Wohlfarth, J. C.; Feldmueller, M.; Schneller, A.; Kilcher, S.; Burkolter, M.; Pilhofer, M.; Schuppler, M.; Loessner, M. J.
10.1101/2022.05.24.493201 — microbiology — Posted on 2022-05-24
1037 LKB1 is the gatekeeper of carotid body chemo-sensing and the hypoxic ventilatory response
MacMillan, S.; Holmes, A. P.; Dallas, M. L.; Mahmoud, A. D.; Shipston, M. J.; Hardie, D. G.; Kumar, P.; Evans, A. M.
10.1101/2022.05.24.493275 — physiology — Posted on 2022-05-24
1040 Unveiling the G4-PAMAM capacity to bind and protect Ang-(1-7) bioactive peptide
Chi Uluac, L. A.; Asgharpour, S.; Correa-Basurto, J.; Bandala, C. R.; Martinez-Archundia, M.
10.1101/2022.05.23.493150 — biophysics — Posted on 2022-05-24
1041 A common mechanism of temperature-sensing in thermoTRP channels
Xu, L.; Liang, X.; Zhen, W.; Xue, Z.; Zhang, F.; Yi, X.; Chen, X.; Hu, L.; Li, B.; Zhang, B.; Wang, Y.; Deng, Z.; Yang, W.; Wen, H.; Guo, T.; Zhu, Y.; Fan, Y.
10.1101/2022.05.23.493163 — biophysics — Posted on 2022-05-24
1046 Porcine placenta extract upregulates ceramide synthase 3 expression via the PPARδ/ILK/Akt/mTOR/STAT3 pathway
Aioi, A.; Muromoto, R.; Kashiwakura, J.-i.; Mogami, S.; Nishikawa, M.; Ogawa, S.; Matsuda, T.
10.1101/2022.05.23.493164 — biochemistry — Posted on 2022-05-24
1049 Context-dependent 3D genome regulation by cohesin and related factors
Nakato, R.; Sakata, T.; Wang, J.; Nagai, L. A. E.; Oba, G. M.; Bando, M.; Shirahige, K.
10.1101/2022.05.24.493188 — genomics — Posted on 2022-05-24
1051 Decreased miRNA-148a-3p expression in skeletal muscle of patients with chronic kidney disease
Robinson, K.; Baker, L.; Graham-Brown, M.; Ashford, R.; Pawluczyk, I.; Major, R.; Burton, J.; Sylvius, N.; Cooper, A.; Philp, A.; Watson, E. L.
10.1101/2022.05.24.493194 — molecular biology — Posted on 2022-05-24
1054 A central role of sibling sRNAs NgncR_162/163 in main metabolic pathways of Neisseria gonorrhoeae
Steiner, T.; Zachary, M.; Bauer, S.; Mueller, M. J.; Krischke, M.; Radziej, S.; Klepsch, M.; Huettel, B.; Eisenreich, W.; Rudel, T.; Beier, D.
10.1101/2022.05.24.492095 — microbiology — Posted on 2022-05-24
1055 Detection of latent Epstein-Barr virus gene expression in single-cell sequencing of peripheral blood mononuclear cells
Bäckerholm, A.; Tian, Y.; Holmqvist, I.; Xie, G.; Vracar, D.; Abrahamsson, S.; Guibentif, C.; Tang, K.-W.
10.1101/2022.05.24.492331 — microbiology — Posted on 2022-05-24
1056 Sex differences in the nasal microbiome of healthy young adults
Ju, Y.; Zhang, Z.; Liu, M.; Lin, S.; Sun, Q.; Song, Z.; Liang, W.; Tong, X.; Jie, Z.; Lu, H.; Cai, K.; Chen, P.; Jin, X.; Xu, X.; Yang, H.; Wang, J.; Hou, Y.; Xiao, L.; Jia, H.; Zhang, T.; Guo, R.
10.1101/2022.05.23.493011 — microbiology — Posted on 2022-05-24
1058 MADET: A Manually Curated Knowledgebase for Microbiomic Effects on Efficacy and Toxicity of Anticancer Treatments
Zhang, J.; Chen, X.; Zou, J.; Li, C.; Kang, W.; Guo, Y.; Liu, S.; Zhao, W.; Mou, X.; Huang, J.; Ke, J.
10.1101/2022.05.23.493174 — microbiology — Posted on 2022-05-24
1059 Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons
Popova, D.; Gameiro-Ros, I.; Youssef, M. M.; Zalamea, P.; Morris, A. D.; Prytkova, I.; Jadali, A.; Kwan, K. Y.; Kamarajan, C.; Salvatore, J. E.; Edenberg, H. J.; Xuei, X.; Chorlian, D. B.; Porjesz, B.; Kuperman, S.; Dick, D. M.; Goate, A.; Tischfield, J. A.; Pang, Z. P.; Slesinger, P. A.; Hart, R. P.
10.1101/2022.05.24.493086 — neuroscience — Posted on 2022-05-24
1060 Design of Peptide-Based Protein Degraders via Contrastive Deep Learning
Palepu, K.; Ponnapati, M.; Bhat, S.; Tysinger, E.; Stan, T.; Brixi, G.; Koseki, S. R. T.; Chatterjee, P.
10.1101/2022.05.23.493169 — synthetic biology — Posted on 2022-05-24
1063 Host-directed therapy with 2-Deoxy-D-glucose inhibits human rhinoviruses, endemic coronaviruses, and SARS-CoV-2
Wali, L.; Karbiener, M.; Chou, S.; Kovtunyk, V.; Adonyi, A.; Goesler, I.; Contreras, X.; Stoeva, D.; Blaas, D.; Stoeckl, J.; Kreil, T. R.; Gualdoni, G. A.; Gorki, A.-D.
10.1101/2022.05.24.493068 — microbiology — Posted on 2022-05-24
1064 RAGE engagement by SARS-CoV-2 enables monocyte infection and underlies COVID-19 severity
Angioni, R.; Bonfanti, M.; Caporale, N.; Sanchez-Rodriguez, R.; Munari, F.; Savino, A.; Buratto, D.; Pagani, I.; Bertoldi, N.; Zanon, C.; Ferrari, P.; Ricciardelli, E.; Putaggio, C.; Ghezzi, S.; Elli, F.; Rotta, L.; Iorio, F.; Zonta, F.; Cattelan, A.; Vicenzi, E.; Molon, B.; Villa, C. E.; Viola, A.; Testa, G.
10.1101/2022.05.22.492693 — immunology — Posted on 2022-05-24
1066 Estimation of Periodic Signals with Applications to Deep Brain Stimulation
Chen, P.; Kim, T.; Goodman, W. K.; Borton, D. A.; Harrison, M. T.; Darbon, J.
10.1101/2022.05.23.493124 — neuroscience — Posted on 2022-05-24
1069 Predicting recognition between T cell receptors and epitopes using contextualized motifs
Jokinen, E.; Dumitrescu, A.; Huuhtanen, J.; Gligorijevic, V.; Heinonen, M.; Mustjoki, S.; Bonneau, R.; Lähdesmäki, H.
10.1101/2022.05.23.493034 — bioinformatics — Posted on 2022-05-24
1072 Development of an In Vitro Test for the Optimization of Drug Diffusion in Pediatric Solid Tumors
Ivy, R.; Hendricks-Wenger, A.; Kennedy, L.; Jones, A.; Riley, D.; Handy, A.; Barker, E. D.
10.1101/2022.05.23.493070 — bioengineering — Posted on 2022-05-24
1073 Cardiac-Gated Spectroscopic Photoacoustic Imaging for Ablation-Induced Necrotic Lesion Visualization: In Vivo Demonstration in a Beating Heart
Gao, S.; Ashikaga, H.; Suzuki, M.; Mansi, T.; Kim, Y.-H.; Ghesu, F.-C.; Kang, J.; Boctor, E. M.; Halperin, H. R.; Zhang, H. K.
10.1101/2022.05.23.492682 — bioengineering — Posted on 2022-05-24
1074 An Igh novel enhancer modulates antigen receptor diversity by determining locus conformation
Bhat, K. H.; Priyadarshi, S.; Naiyer, S. L.; Qu, X.; Faroque, H.; Kleiman, E.; Xu, J.; Lei, X.; Cantillo, J. F.; Wuerffel, R.; Baumgarth, N.; Liang, J.; Kenter, A. L.; Feeney, A.
10.1101/2022.05.23.492988 — immunology — Posted on 2022-05-24
1075 Perceptual decisions exhibit hallmarks of dynamic Bayesian inference
Charlton, J. A.; Młynarski, W. F.; Bai, Y. H.; Hermundstad, A. M.; Goris, R. L. T.
10.1101/2022.05.23.493109 — neuroscience — Posted on 2022-05-24
1077 The effects of combined action observation and motor imagery on corticospinal excitability and movement outcomes: A meta-analysis
Chye, S.; Chembila Valappil, A.; Wright, D. J.; Frank, C.; Shearer, D. A.; Tyler, C. J.; Diss, C. E.; Mian, O.; Tillin, N.; Bruton, A. M.
10.1101/2022.05.23.493106 — neuroscience — Posted on 2022-05-24
1080 In vivo selection reveals long non-coding RNAs implicated in colon to liver metastasis
Soroosh, A.; Padua, D. M.; Videlock, E.; Bui, D.; Patel, A.; Pothoulakis, C.; Rankin, C. R.
10.1101/2022.05.23.493110 — cancer biology — Posted on 2022-05-24
1081 Tristetraproline in breast cancer: treat or trick?
Kropyvko, S.; Hubiernatorova, A.; Mankovska, O.; Syvak, L.; Verovkina, N.; Lyalkin, S.; Lavrynenko, K.; Ivasechko, I.; Stoika, R.; Rynditch, A.
10.1101/2022.05.23.493030 — cancer biology — Posted on 2022-05-24
1083 Whole-Genome RNA Sequencing of Femoral Head Impingement Cartilage Identifies FGF18 As A Biomarker in Hip Osteoarthritis Progression
Kuhns, B. D.; Reuter, J. M.; Hansen, V. L.; Soles, G.; Jonason, J. H.; Ackert-Bicknell, C. L.; Wu, C.-L.; Giordano, B. D.
10.1101/2022.05.23.492951 — bioinformatics — Posted on 2022-05-24
1087 Thirty years of deforestation within the entire ranges of nine endangered lemur species (3 CR, 4 EN, 2 VU) in northwestern Madagascar
Schuessler, D.; Andriamalala, Y. R.; van der Bach, R.; Katzur, C.; Kolbe, C.; Maheritafika, M. H. R.; Rasolozaka, M.; Razafitsalama, M.; Renz, M.; Steffens, T. S.; Radespiel, U.; Brenner, J.
10.1101/2022.05.23.493111 — ecology — Posted on 2022-05-24
1090 Video-based automated analysis of MDS-UPDRS III parameters in Parkinson disease
Vignoud, G.; Desjardins, C.; Salardaine, Q.; Mongin, M.; Garcin, B.; Venance, L.; Degos, B.
10.1101/2022.05.23.493047 — neuroscience — Posted on 2022-05-24
1091 Intrinsic excitability in layer IV-VI anterior insula to basolateral amygdala projection neurons encodes the confidence of taste valence
Chandran, S. K.; Yiannakas, A.; Kayyal, H.; Salalha, R.; Cruciani, F.; Mizrahi, L.; Khamaisy, M.; Stern, S.; Rosenblum, K.
10.1101/2022.05.23.493046 — neuroscience — Posted on 2022-05-24
1092 Differential impact of brain network efficiency on post-stroke motor and attentional deficits
Evangelista, G. G.; Egger, P.; Bruegger, J.; Beanato, E.; Koch, P. J.; Ceroni, M.; Fleury, L.; Cadic-Melchior, A.; Meyer, N. H.; de Leon Rodriguez, D.; Girard, G.; Leger, B.; Turlan, J.-L.; Muehl, A.; Vuadens, P.; Adolphsen, J.; Jagella, C.; Constantin, C.; Alvarez, V.; Ghika, J.-A.; San Millan, D.; Bonvin, C.; Morishita, T.; Wessel, M. J.; Van de Ville, D.; Hummel, F.
10.1101/2022.05.23.493043 — neuroscience — Posted on 2022-05-24
1094 Resilient anatomy and local microplasticity of naïve and stress hematopoiesis
Wu, Q.; Zhang, J.; Johnson, C. B.; Slaughter, A.; Weinhaus, B.; McKnight, M.; Sherman, B. E.; Shao, T.-y.; Song, B.; Filippi, M. D.; Grimes, H. L.; Way, S. S.; Kofron, J. M.; Lucas, D.
10.1101/2022.05.23.492315 — physiology — Posted on 2022-05-24
1095 Effect of biomaterial stiffness on cardiac mechanics in a biventricular infarcted rat heart model with microstructural representation of in situ intramyocardial injectate
Motchon, Y. D.; Sack, K. L.; Sirry, M. S.; Kruger, M.; Pauwels, E.; Van Loo, D.; De Muynck, A.; Van Hoorebeke, L.; Davies, N. H.; Franz, T.
10.1101/2022.05.23.493036 — biophysics — Posted on 2022-05-24
1098 gExcite - A start-to-end framework for single-cell gene expression, hashing, and antibody analysis
Grob, L.; Bertolini, A.; Carrara, M.; Menzel, U.; Tastanova, A.; Beisel, C.; Levesque, M. P.; Stekhoven, D. J.; Singer, F.
10.1101/2022.05.23.490488 — bioinformatics — Posted on 2022-05-24
1100 Highly divergent white-tailed deer SARS-CoV-2 with potential deer-to-human transmission
Pickering, B.; Lung, O.; Maguire, F.; Kruczkiewicz, P.; Kotwa, J. D.; Buchanan, T.; Gagnier, M.; Guthrie, J.; Jardine, C.; Marchand-Austin, A.; Masse, A.; McClinchey, H.; Nirmalarajah, K.; Aftanas, P.; Blais-Savoie, J.; Chee, H.-Y.; Chien, E.; Yim, W.; Banete, A.; Griffin, B. D.; Yip, L.; Goolia, M.; Suderman, M.; Pinette, M.; Smith, G.; Sullivan, D.; Rudar, J.; Adey, E.; Nebroski, M.; Goyette, G.; Finzi, A.; Laroche, G.; Ariana, A.; Vahkal, B.; Cote, M.; McGeer, A.; Nituch, L.; Mubareka, S.; Bowman, J.
10.1101/2022.02.22.481551 — microbiology — Posted on 2022-05-24
1104 Multilevel selection leads to divergent coadaptation of care-giving parents during pre-hatching parental care
Jarrett, B. J. M.; Mashoodh, R.; Issar, S.; Pascoal, S.; Rebar, D.; Sun, S.-J.; Schrader, M.; Kilner, R. M.
10.1101/2022.05.23.493134 — evolutionary biology — Posted on 2022-05-24
1107 Identification of novel basil downy mildew resistance genes using de novo comparative transcriptomics
Allen, K. S.; DeIulio, G. A.; Pyne, R.; Maman, J.; Guo, L.; Wick, R. L.; Simon, J.; Gershenson, A.; Ma, L.-J.
10.1101/2022.05.23.491563 — plant biology — Posted on 2022-05-24
1109 Cellular segregation in co-cultures driven by differential adhesion and contractility on distinct time scales
Skamrahl, M.; Schuenemann, J.; Mukenhirn, M.; Gottwald, J.; Ferle, M.; Ruebeling, A.; Honigmann, A.; Janshoff, A.
10.1101/2022.05.23.492966 — biophysics — Posted on 2022-05-24
1111 PKN2 deficiency leads both to prenatal congenital cardiomyopathy and defective angiotensin II stress responses.
Marshall, J. J.; Cull, J. J.; Alharbi, H. O.; Zaw Thin, M.; Cooper, S. T.; Barrington, C.; Vanyai, H.; Snoeks, T.; Siow, B.; Suaarez-Bonnet, A.; Herbert, E.; Stuckey, D. J.; Cameron, A.; Prin, F.; Cook, A. C.; Priestnall, S. L.; Chotani, S.; Rackham, O. J.; Meijles, D. N.; Mohun, T.; Clerk, A.; Parker, P.
10.1101/2022.05.24.493130 — developmental biology — Posted on 2022-05-24
1115 Morphological profiling by high-throughput single-cell biophysical fractometry
Zhang, Z.; Lee, K. C. M.; Siu, D. M. D.; Lai, Q. T. K.; Lam, E. Y. M.; Tsia, K. K. M.
10.1101/2022.05.24.493226 — cell biology — Posted on 2022-05-24
1118 Metformin improves glycemia independently of skeletal muscle AMPK via enhanced intestinal glucose clearance
Kjobsted, R.; Kristensen, J. M.; Birk, J. B.; Jorgensen, N. O.; Kido, K.; Andersen, N. R.; Larsen, J. K.; Foretz, M.; Benoit, V.; Nielsen, F.; Brosen, K.; Jessen, N.; Hellsten, Y.; Hojlund, K.; Wojtaszewski, J. F. P.
10.1101/2022.05.22.492936 — physiology — Posted on 2022-05-24
1123 BOA: A Partitioned View of Genome Assembly
Ghosh, P.; An, X.; Keppler, P.; Emre Kurt, S.; Catalyurek, U. V.; Krishnamoorthy, S.; Sadayappan, P.; Rajam, A. S.; Kalyanaraman, A.
10.1101/2022.05.22.492973 — genomics — Posted on 2022-05-24
1124 Machine-learning dissection of Human Accelerated Regions in primate neurodevelopment
Whalen, S.; Inoue, F.; Ryu, H.; Fair, T.; Markenscoff-Papadimitriou, E.; Keough, K.; Kircher, M.; Martin, B.; Alvarado, B.; Elor, O.; Cintron, D. L.; Williams, A.; Samee, M. A. H.; Thomas, S.; Krencik, R.; Ullian, E.; Kriegstein, A.; Shendure, J.; Pollen, A.; Ahituv, N.; Pollard, K.
10.1101/256313 — evolutionary biology — Posted on 2022-05-24
1127 EP300 (p300) mediated histone butyrylation is critical for adipogenesis
Kundu, T. K.; Bhattacharya, A.; Chatteerjee, S.; Bhaduri, U.; Singh, A. K.; Vasudevan, M.; Sashidhara, K. V.; Guha, R.; Natesh, N.; Nazir, A.; Rath, S. K.
10.1101/2021.08.01.454641 — molecular biology — Posted on 2022-05-24
1130 Food for thought: selectivity for food in human ventral visual cortex
Jain, N.; Wang, A.; Henderson, M. M.; Lin, R.; Prince, J. S.; Tarr, M. J.; Wehbe, L.
10.1101/2022.05.22.492983 — neuroscience — Posted on 2022-05-24
1134 Vitamin D constrains inflammation by modulating the expression of key genes on Chr17q12-21.1
Kılıc, A.; Halu, A.; De Marzio, M.; Maiorino, E.; Duvall, M. G.; Brüggemann, T. R.; Rojas Quintero, J. J.; Chase, R.; Mirzakhani, H.; Özge Sungur, A.; Koepke, J.; Nakano, T.; Peh, H. Y.; Krishnamoorthy, N.; Abdulnour, R.-E.; Georgopoulos, K.; Litonjua, A. A.; Demay, M. B.; Renz, H.; Levy, B. D.; Weiss, S. T.
10.1101/2022.05.22.491886 — systems biology — Posted on 2022-05-24
1135 Somatic copy number variant load in neurons of healthy controls and Alzheimer's disease patients
Turan, Z. G.; Richter, V.; Bochmann, J.; Parvizi, P.; Yapar, E.; Isıldak, U.; Waterholter, S. K.; Turbant, S. L.; Son, C. D.; Duyckaerts, C.; Yet, I.; Arendt, T.; Somel, M.; Ueberham, U.
10.1101/2022.05.20.492539 — bioinformatics — Posted on 2022-05-24
1141 HiFi reads and Hi-C data facilitate haplotype-phrased and chromosome-scale assembly of Puccinia polysora, the fungal pathogen of southern corn rust
Liang, j.; Li, y.; Dodds, P. N.; Figueroa, M.; Sperschneider, J.; Han, S.; Tsui, C. K. M.; Zhang, K.; Li, L.; Ma, Z.; Cai, L.
10.1101/2022.05.18.492400 — genomics — Posted on 2022-05-24
1143 Social Regulation of Egg Size Plasticity in the Honey Bee is Mediated by Cytoskeleton Organizer Rho1
Han, B.; Wei, Q.; Amiri, E.; Hu, H.; Lifeng, M.; Strand, M.; Tarpy, D. R.; Xu, S.; li, J.; Rueppell, O.
10.1101/2022.05.22.492980 — evolutionary biology — Posted on 2022-05-24
1144 Assessing risk for butterflies in the context of climate change, demographic uncertainty, and heterogenous data sources
Forister, M. L.; Grames, E. M.; Halsch, C. A.; Burls, K. J.; Carroll, C. F.; Bell, K. L.; Jahner, J. P.; Bradford, T.; Zhang, J.; Cong, Q.; Grishin, N. V.; Glassberg, J.; Shapiro, A. M.; Riecke, T. V.
10.1101/2022.05.22.492972 — ecology — Posted on 2022-05-24
1146 NaCl Triggers the Sessile-to-Motile Transition of Bacillus subtilis
Murugan, P. A.; Gupta, M. K.; Sankar, T. S.; Chandran, S.; Matheshwaran, S.
10.1101/2022.02.15.480532 — microbiology — Posted on 2022-05-24
1148 Physical resilience in the brain: The effect of white matter disease on brain networks in cognitively normal older adults
Neyland, B. R.; Lockhart, S. N.; Lyday, R. G.; Baker, L. D.; Handing, E. P.; Miller, M. E.; Kritchevsky, S. B.; Laurienti, P. J.; Hugenschmidt, C. E.
10.1101/2022.05.20.492850 — neuroscience — Posted on 2022-05-24
1152 Impaired Epigenesis of Imprinting Predispositions Causes Autism-like Behavioral Phenotypes in Domestic Chicks
Matsushima, T.; Miura, M.; Patzke, N.; Toji, N.; Wada, K.; Ogura, Y.; Homma, K. J.; Sgado, P.; Vallortigara, G.
10.1101/2022.05.19.492744 — animal behavior and cognition — Posted on 2022-05-24
1154 Event-driven acquisition for content-enriched microscopy
Mahecic, D.; Stepp, W. L.; Zhang, C.; Griffie, J.; Weigert, M.; Manley, S.
10.1101/2021.10.04.463102 — cell biology — Posted on 2022-05-24
1157 ABHD6 selectively controls metabotropic-dependent increases in 2-AG production
Singh, S.; Sarroza, D.; English, A.; Whittington, D.; Dong, A.; van der Stelt, M.; Li, Y.; Zweifel, L.; Bruchas, M. R.; Land, B. B.; Stella, N.
10.1101/2022.05.18.492553 — cell biology — Posted on 2022-05-23
1158 Association of lanthipeptide genes with TnpAREP transposases in marine picocyanobacteria
Laurenceau, R.; Raho, N.; Cariani, Z.; Bliem, C.; Kearney, S. M.; Thomas, E.; Osman, M. A. M.; Chisholm, S. W.
10.1101/2020.03.09.984088 — microbiology — Posted on 2022-05-23
1159 Further antibody escape by Omicron BA.4 and BA.5 from vaccine and BA.1 serum
Tuekprakhon, A.; Huo, J.; Nutalai, R.; Dijokaite-Guraliuc, A.; Zhou, D.; Ginn, H. M.; Sekvaraj, M.; Liu, C.; Mentzer, A. J.; Supasa, P.; Duyvesteyn, H. M. E.; Das, R.; Skelly, D.; Ritter, T. G.; Amini, A.; Bibi, S.; Adele, S.; Johnson, S. A.; Constantinides, B.; Webster, H.; Temperton, N.; Klenerman, P.; Barnes, E.; Dunachie, S. J.; Crook, D.; Pollard, A. J.; Lambe, T.; Goulder, P.; OPTIC consortium, ; ISARIC4C consortium, ; Fry, E. E.; Mongkolsapaya, J.; Ren, J.; Stuart, D. I.; Screaton, G. R.
10.1101/2022.05.21.492554 — microbiology — Posted on 2022-05-23
1160 A global atlas of substrate specificities for the human serine/threonine kinome
Johnson, J. L.; Yaron, T. M.; Huntsman, E. M.; Kerelsky, A.; Song, J.; Regev, A.; Lin, T.-Y.; Liberatore, K.; Cizin, D. M.; Cohen, B. M.; Vasan, N.; Ma, Y.; Krismer, K.; Torres Robles, J.; van de Kooij, B.; van Vlimmeren, A. E.; Andree-Busch, N.; Käufer, N. F.; Dorovkov, M. V.; Ryazanov, A. G.; Takagi, Y.; Kastenhuber, E. R.; Goncalves, M. D.; Elemento, O.; Taatjes, D. J.; Maucuer, A.; Yamashita, A.; Degterev, A.; Blenis, J.; Hornbeck, P. V.; Turk, B. E.; Yaffe, M. B.; Cantley, L. C.
10.1101/2022.05.22.492882 — systems biology — Posted on 2022-05-23
1162 Intrinsically disordered interaction network in an RNA chaperone revealed by native mass spectrometry
Sarni, S. H.; Roca, J.; Du, C.; Jia, M.; Li, H.; Damjanovic, A.; Małecka, E.; Wysocki, V.; Woodson, S. A.
10.1101/2022.05.23.493136 — biophysics — Posted on 2022-05-23
1164 Native size exclusion chromatography-based mass spectrometry (SEC-MS) identifies novel components of the Heat Shock Protein 90-dependent proteome
Samant, R. S.; Batista, S.; Larance, M.; Ozer, B.; Milton, C. I.; Bludau, I.; Biggins, L.; Andrews, S.; Hervieu, A.; Johnston, H. E.; Al-Lazikhani, B.; Lamond, A. I.; Clarke, P. A.; Workman, P.
10.1101/2022.05.23.492985 — biochemistry — Posted on 2022-05-23
1165 Rates and spectra of de novo structural mutation in Chlamydomonas reinhardtii
Lopez-Cortegano, E.; Craig, R.; Chebib, J.; Balogun, E. J.; Keightley, P. D.
10.1101/2022.05.23.493040 — evolutionary biology — Posted on 2022-05-23
1169 Rapid, in-patient adaptations of Legionella pneumophila to the human host
Leenheer, D.; Moreno, A. B.; Murray, S.; Jarraud, S.; Ginevra, C.; Guy, L.
10.1101/2022.05.23.492981 — microbiology — Posted on 2022-05-23
1170 Uncovering Lasonolide A biosynthesis using genome-resolved metagenomics
Uppal, S.; Metz, J. L.; Xavier, R. K. M.; Nepal, K.; Xu, D.; Wang, G.; Kwan, J. C.
10.1101/2022.05.23.493085 — microbiology — Posted on 2022-05-23
1171 A cryptic transcription factor regulates Caulobacter adhesin development
McLaughlin, M.; Hershey, D.; Reyes-Ruiz, L.; Fiebig, A.; Crosson, S.
10.1101/2022.05.23.493133 — microbiology — Posted on 2022-05-23
1172 Clonal spreading of tumor-infiltrating T cells underlies the robust antitumor immune responses
Aoki, H.; Tsunoda, M.; Ogiwara, H.; Shimizu, H.; Abe, H.; Abe, T.; Shichino, S.; Matsushima, K.; Ueha, S.
10.1101/2022.04.19.488731 — immunology — Posted on 2022-05-23
1174 Autoimmune Alleles at the Major Histocompatibility Locus Modify Melanoma Susceptibility
Talwar, J.; Laub, D.; Pagadala, M.; Castro, A.; Lewis, M.; Luebeck, G. E.; Gorman, B.; Pan, C.; Dong, F. N.; Markianos, K.; Hauger, R.; Pyarajan, S.; Tsao, P. S.; Morris, G. P.; Salem, R. M.; Thompson, W. K.; Curtius, K.; Zanetti, M.; Carter, H.
10.1101/2021.08.12.456166 — cancer biology — Posted on 2022-05-23
1175 MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas
Stopfer, L. E.; Rettko, N.; Leddy, O.; Mesfin, J. M.; Brown, E.; Winski, S.; Bryson, B. D.; Wells, J. A.; White, F.
10.1101/2022.01.10.475285 — cancer biology — Posted on 2022-05-23
1177 The interface of condensates of the hnRNPA1 low complexity domain promotes formation of amyloid fibrils
Linsenmeier, M.; Faltova, L.; Capasso Palmiero, U.; Seiffert, C.; Kueffner, A. M.; Pinotsi, D.; Zhou, J.; Mezzenga, R.; Arosio, P.
10.1101/2022.05.23.493075 — biophysics — Posted on 2022-05-23
1178 Structural characterization of a breast cancer-associated mutation in caveolin-1
Han, B.; Gulsevin, A.; Connolly, S.; Wang, T.; Porta, J.; Tiwari, A.; Deng, A.; Chang, L.; Peskova, Y.; Mchaourab, H.; Karakas, E.; Ohi, M. D.; Meiler, J.; Kenworthy, A. K.
10.1101/2022.05.23.493104 — biophysics — Posted on 2022-05-23
1179 Predictions of immunogenicity reveal potent SARS-CoV-2 CD8+ T-cell epitopes
Gfeller, D.; Schmidt, J.; Croce, G.; Guillaume, P.; Bobisse, S.; Genolet, R.; Queiroz, L.; Cesbron, J.; Racle, J.; Harari, A.
10.1101/2022.05.23.492800 — bioinformatics — Posted on 2022-05-23
1187 Dynamic bimodality of curli expression in planktonic cultures of Escherichia coli is stabilized by cyclic-di-GMP regulation
Lamprecht, O.; Ratnikava, M.; Jacek, P.; Kaganovitch, E.; Buettner, N.; Fritz, K.; Köhler, R.; Pietsch, J.; Sourjik, V.
10.1101/2022.05.23.493020 — microbiology — Posted on 2022-05-23
1189 Anti-chemokine antibodies after SARS-CoV-2 infection correlate with favorable disease course
Muri, J.; Cecchinato, V.; Cavalli, A.; Shanbhag, A. A.; Matkovic, M.; Biggiogero, M.; Maida, P. A.; Toscano, C.; Ghovehoud, E.; Danelon-Sargenti, G.; Gong, T.; Piffaretti, P.; Bianchini, F.; Crivelli, V.; Podesvova, L.; Pedotti, M.; Jarrossay, D.; Sgrignani, J.; Thelen, S.; Uhr, M.; Bernasconi, E.; Rauch, A.; Manzo, A.; Ciurea, A.; Rocchi, M. B. L.; Varani, L.; Moser, B.; Thelen, M.; Garzoni, C.; Franzetti-Pellanda, A.; Uguccioni, M.; Robbiani, D. F.
10.1101/2022.05.23.493121 — immunology — Posted on 2022-05-23
1190 Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine candidate is protective in macaques
Le Nouen, C.; Nelson, C. E.; Liu, X.; Park, H.-S.; Matsuoka, Y.; Luongo, C.; Santos, C.; Yang, L.; Herbert, R.; Castens, A.; Moore, I. N.; Wilder-Kofie, T.; Moore, R.; Walker, A.; Zhang, P.; Lusso, P.; Johnson, R. F.; Garza, N. L.; Via, L. E.; Munir, S.; Barber, D.; Buchholz, U. J.
10.1101/2022.05.21.492923 — immunology — Posted on 2022-05-23
1191 The SARS-CoV-2 spike protein binds and modulates estrogen receptors
Solis, O.; Beccari, A. R.; Iaconis, D.; Talarico, C.; Ruiz-Bedoya, C. A.; Nwachukwu, J. C.; Cimini, A.; Castelli, V.; Bertini, R.; Montopoli, M.; Cocetta, V.; Borocci, S.; Prandi, I. G.; Flavahan, K.; Bahr, M.; Napiorkowski, A.; Chillemi, G.; Ooka, M.; Yang, X.; Zhang, S.; Xia, M.; Zheng, W.; Bonaventura, J.; Pomper, M. G.; Hooper, J. E.; Morales, M.; Rosenberg, A. Z.; Nettles, K. W.; Jain, S. K.; Allegretti, M.; Michaelides, M.
10.1101/2022.05.21.492920 — immunology — Posted on 2022-05-23
1192 Tissue-specific modifier alleles determine Mertk loss-of-function traits
Akalu, Y. T.; Mercau, M. E.; Ansems, M.; Wagage, S.; Hughes, L. D.; Nevin, J.; Alberto, E. J.; Liu, X. E.; He, L.-Z.; Alvarado, D.; Keler, T.; Kong, Y.; Philbrick, W. M.; Finnemann, S. C.; Iavarone, A.; Lasorella, A.; Rothlin, C. V.; Ghosh, S.
10.1101/2022.05.23.493101 — immunology — Posted on 2022-05-23
1193 Reduced Neutralization of SARS-CoV-2 Omicron Variant in Sera from SARS-CoV-1 Survivors after 3-dose of Vaccination
Zhao, X.; Chen, D.; Hao, X.; Qiu, Y.; Du, J.; Zhang, Y.; Xiao, F.; Li, X.; Song, Y.; Song, R.; Wang, X.; Jin, R.
10.1101/2022.05.21.492903 — immunology — Posted on 2022-05-23
1196 Namco: A microbiome explorer
Dietrich, A.; Matchado, M. S.; Zwiebel, M.; Ölke, B.; Lauber, M.; Lagkouvardos, I.; Baumbach, J.; Haller, D.; Brandl, B.; Skurk, T.; Hauner, H.; Reitmeier, S.; List, M.
10.1101/2021.12.15.471754 — bioinformatics — Posted on 2022-05-23
1199 The genomics and physiology of abiotic stressors associated with global elevation gradients in Arabidopsis thaliana
Gamba, D.; Lorts, C.; Haile, A.; Sahay, S.; Lopez, L.; Xia, T.; Kulesza, E.; Elango, D.; Kerby, J.; Yifru, M.; Bulafu, C. E.; Wondimu, T.; Glowacka, K.; Lasky, J.
10.1101/2022.03.22.485410 — evolutionary biology — Posted on 2022-05-23
1201 Hunter-gatherer oral microbiomes are shaped by contact network structure
Musciotto, F.; Dobon, B.; Greenacre, M.; Mira, A.; Chaudhary, N.; Salali, G. D.; Gerbault, P.; Schlaepfer, R.; Astete, L. H.; Gomez-Gardenes, J.; Latora, V.; Battiston, F.; Bertranpetit, J.; Vinicius, L.; Migliano, A. B.
10.1101/2022.05.03.489993 — microbiology — Posted on 2022-05-23
1202 The making of the oral microbiome in Agta hunter-gatherers
Dobon, B.; Musciotto, F.; Mira, A.; Greenacre, M.; Schlaepfer, R.; Aguileta, G.; Astete, L. H.; Ngales, M.; Latora, V.; Battiston, F.; Vinicius, L.; Migliano, A. B.; Bertranpetit, J.
10.1101/2022.05.03.490437 — microbiology — Posted on 2022-05-23
1203 Immediate and sustained effects of cobalt and zinc-containing pigments on macrophages
Devcic, J.; Dussol, M.; Collin-Faure, V.; Perard, J.; Fenel, D.; Schoehn, G.; Carriere, M.; Rabilloud, T.; Dalzon, B.
10.1101/2021.04.20.440447 — immunology — Posted on 2022-05-23
1208 Endothelial Rbpj is essential for the education of tumour-associated macrophages
Mülfarth, R.; Alsina-Sanchis, E.; Moll, I.; Böhn, S.; Wiedmann, L.; Jordana Urriza, L.; Ziegelbauer, T.; Taylor, J.; De Angelis Rigotti, F.; Stögbauer, A.; Giaimo, B. D.; Cerwenka, A.; Borggrefe, T.; Fischer, A.; Rodriguez-Vita, J.
10.1101/2021.12.20.473423 — cancer biology — Posted on 2022-05-23
1209 Disease classification for whole blood DNA methylation: meta-analysis, missing values imputation, and XAI
Kalyakulina, A.; Yusipov, I.; Bacalini, M. G.; Franceschi, C.; Vedunova, M.; Ivanchenko, M.
10.1101/2022.05.10.491404 — bioinformatics — Posted on 2022-05-23
1210 Incilius alvarius cell-based synthesis of 5-MeO-DMT
Lerer, L.; Reynolds, E.; Varia, J.; Blakolmer, K.; Lerer, B.
10.1101/2022.05.20.492789 — bioengineering — Posted on 2022-05-23
1211 Raman2RNA: Live-cell label-free prediction of single-cell RNA expression profiles by Raman microscopy
Kobayashi-Kirschvink, K. J.; Gaddam, S.; James-Sorenson, T.; Grody, E.; Ounadjela, J. R.; Ge, B.; Zhang, K.; Kang, J. W.; Xavier, R.; So, P. T. C.; Biancalani, T.; Shu, J.; Regev, A.
10.1101/2021.11.30.470655 — genomics — Posted on 2022-05-23
1212 Interplay between PML NBs and HIRA for H3.3 dynamics following type I interferon stimulus
Kleijwegt, C.; Bressac, F.; Cohen, C.; Texier, P.; Simonet, T.; Schaeffer, L.; Lomonte, P.; Corpet, A.
10.1101/2021.11.30.470516 — genetics — Posted on 2022-05-23
1215 Visualizing Molecules of Functional Human Profilin
Pimm, M. L.; Liu, X.; Tuli, F.; Heritz, J.; Lojko, A.; Henty-Ridilla, J. L.
10.1101/2021.09.01.458557 — cell biology — Posted on 2022-05-23
1216 Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration
Travis, A. M.; Manocha, S.; Willer, J. R.; Wessler, T. S.; Skiba, N. P.; Pearring, J.
10.1101/2022.05.02.490367 — cell biology — Posted on 2022-05-23
1217 The C-type Lectin Receptor Dectin-2 is a receptor for Aspergillus fumigatus galactomannan
Reedy, J. L.; Crossen, A. J.; Negoro, P. E.; Brown, H. E.; Ward, R. A.; Blanco, D. A. V.; Timmer, K. D.; Mansour, M. K.; Wüthrich, M.; Fontaine, T.; Latgé, J.-P.; Vyas, J. M.
10.1101/2022.04.12.488040 — immunology — Posted on 2022-05-23
1219 Population-level differences in the neural substrates supporting Statistical Learning
Orpella, J.; Assaneo, M. F.; Ripolles, P.; Noejovich, L.; Lopez-Barroso, D.; de Diego Balaguer, R.; Poeppel, D.
10.1101/2020.07.03.187260 — neuroscience — Posted on 2022-05-23
1222 Boosting chloroplast ribosome biogenesis by a plastidial DEAD-box RNA helicase is critical for high light acclimation
Djouani-Tahri, E. B.; Nellaepalli, S.; Auroy, P.; Billon, E.; Burlacot, A.; Chaux-Jukic, F.; Cuine, S.; Epting, V.; Huleux, M.; Ghysels, B.; Schulz-Raffelt, M.; Te, I.; Brugiere, S.; Coute, Y.; Takahashi, Y.; Li-Beisson, Y.; Peltier, G.
10.1101/2022.05.16.492170 — plant biology — Posted on 2022-05-23
1223 Semaphorin 3C exacerbates liver fibrosis
De Angelis Rigotti, F.; Wiedmann, L.; Hubert, M. O.; Vacca, M.; Hasan, S. S.; Moll, I.; Carvajal, S.; Jimenez, W.; Starostecka, M.; Billeter, A. T.; Müller-Stich, B.; Wolff, G.; Ekim-Üstünel, B.; Herzig, S.; Mogler, C.; Fischer, A.; Rodriguez-Vita, J.
10.1101/2021.07.29.454292 — pathology — Posted on 2022-05-23
1224 Induction of pancreatic neoplasia in the KRAS/TP53 Oncopig
Mondal, P.; Patel, N.; Bailey, K.; Aravind, S.; Hollingsworth, M. A.; Lazenby, A. J.; Carlson, M. A.
10.1101/2020.05.29.123547 — cancer biology — Posted on 2022-05-23
1226 Controversy over the decline of arthropods: a matter of temporal baseline?
Duchenne, F.; Porcher, E.; Mihoub, J.-B.; Loïs, G.; Fontaine, C.
10.1101/2022.02.09.479422 — ecology — Posted on 2022-05-23
1234 Single-Cell Transcriptome Analyses Reveal the Cell Diversity and Developmental Features of Human Gastric and Metaplastic Mucosa
Tsubosaka, A.; Komura, D.; Katoh, H.; Kakiuchi, M.; Onoyama, T.; Yamamoto, A.; Abe, H.; Seto, Y.; Ushiku, T.; Ishikawa, S.
10.1101/2022.05.22.493006 — genomics — Posted on 2022-05-23
1236 Bayesian species distribution models integrate presence-only and presence-absence data to predict deer distribution and relative abundance.
Morera-Pujol, V.; Mostert, P. S.; Murphy, K.; Burkitt, T.; Coad, B.; McMahon, B. J.; Nieuwenhuis, M.; Morelle, K.; Ward, A.; Ciuti, S.
10.1101/2022.05.23.493051 — ecology — Posted on 2022-05-23
1239 Deconstructing cold-induced brown adipocyte neogenesis in mice
Burl, R. B.; Rondini, E. A.; Wei, H.; Pique-Regi, R.; Granneman, J. G.
10.1101/2022.05.23.493054 — cell biology — Posted on 2022-05-23
1240 PP6-regulated Aurora A activity towards NDC80 limits mitotic spindle size to prevent micronucleation
Sobajima, T.; Kowalczyk, K.; Skylakakis, S.; Hayward, D.; Fulcher, L. J.; Neary, C.; Batley, C.; Roberts, E.; Kurlekar, S.; Gruneberg, U.; Barr, F. A.
10.1101/2022.05.23.492953 — cell biology — Posted on 2022-05-23
1241 Hetero-oligomerization of TDP-43 carboxy-terminal fragments with cellular proteins contributes to proteotoxicity
Kitamura, A.; Fujimoto, A.; Kawashima, R.; Lyu, Y.; Moriya, K.; Kurata, A.; Takahashi, K.; Brielmann, R.; Bott, L. C.; Morimoto, R. I.; Kinjo, M.
10.1101/2022.05.22.493003 — molecular biology — Posted on 2022-05-23
1242 Deep mutational scanning of essential bacterial proteins can guide antibiotic development
Dewachter, L.; Brooks, A. N.; Noon, K.; Krishnamurthy, N.; Versees, W.; Vranken, W.; Michiels, J.
10.1101/2022.05.23.493065 — microbiology — Posted on 2022-05-23
1245 Neuroanatomical and Functional Consequences of Oxytocin Treatment at Birth
Kenkel, W.; Ortiz, R.; Yee, J. R.; Perkeybile, A. M.; Kulkarni, P.; Carter, C. S.; Ferris, C. F.
10.1101/2022.05.21.492438 — neuroscience — Posted on 2022-05-23
1246 Oxytocin activity in the Paraventricular and Supramammillary Nuclei of the Hypothalamus is Essential for Social Recognition Memory in Rats
Thirtamara Rajamani, K.; Barbier, M.; Lefevre, A.; Niblo, K.; Cordero, N.; Netser, S.; Grinevich, V.; Wagner, S.; Harony-Nicolas, H.
10.1101/2022.05.23.493099 — neuroscience — Posted on 2022-05-23
1248 A critical role for touch neurons in a skin-brain pathway for stress resilience
Schaffler, M. D.; Johnson, M.; Hing, B.; Kahler, P.; Hultman, I.; Srivastava, S.; Arnold, J.; Blendy, J. N.; Hultman, R.; Abdus-Saboor, I.
10.1101/2022.05.23.493062 — neuroscience — Posted on 2022-05-23
1250 Lactate supply overtakes glucose when neural computational and cognitive loads scale up
Dembitskaya, Y.; Piette, C.; Perez, S.; Berry, H.; Magistretti, P.; Venance, L.
10.1101/2022.05.23.493059 — neuroscience — Posted on 2022-05-23
1251 Involvement of nucleus accumbens D2-MSN projections to the ventral pallidum in anxious-like behavior
Correia, R.; Domingues, A. V.; Coimbra, B.; Vieitas-Gaspar, N.; Sousa, N.; Pinto, L.; Rodrigues, A. J.; Soares-Cunha, C.
10.1101/2022.05.23.493058 — neuroscience — Posted on 2022-05-23
1253 Phenotypic variation and quantitative trait loci for resistance to southern anthracnose and clover rot in red clover
Frey, L. A.; Vleugels, T.; Ruttink, T.; Schubiger, F. X.; Pegard, M.; Skot, L.; Grieder, C.; Studer, B.; Roldan-Ruiz, I.; Koelliker, R.
10.1101/2022.05.23.493028 — plant biology — Posted on 2022-05-23
1254 A Murine Model of Abductor Insufficiency Accelerates the Development of Hip Osteoarthritis
Geary, M. B.; Orner, C. A.; Shammas, H.; Loiselle, A. E.; Giordano, B. D.; Wu, C.-L.
10.1101/2022.05.22.492940 — pathology — Posted on 2022-05-23
1255 Contrasting parental roles shape sex differences in poison frog space use but not navigational performance
Pasukonis, A.; Serrano-Rojas, S. J.; Fischer, M.-T.; Loretto, M.-C.; Shaykevich, D. A.; Rojas, B.; Ringler, M.; Roland, A.-B.; Marcillo-Lara, A.; Ringler, E.; Rodriguez, C.; Coloma, L. A.; O'Connell, L. A.
10.1101/2022.05.21.492915 — animal behavior and cognition — Posted on 2022-05-23
1256 An iPSC library from a family with Creutzfeldt-Jakob disease caused by the E200K mutation
Le, N. T.; Mercer, R. C.; Gojanovich, A. D.; Park, S.; Wu, B.; Mostoslavsky, G.; Harris, D. A.
10.1101/2022.05.20.491674 — neuroscience — Posted on 2022-05-23
1258 Revealing druggable cryptic pockets in the Nsp-1 of SARS-CoV-2 and other β-coronaviruses by simulations and crystallography
Borsatto, A.; Akkad, O.; Galdadas, I.; Ma, S.; Damfo, S.; Haider, S.; Kozielski, F.; Estarellas, C.; Gervasio, F. L.
10.1101/2022.05.20.492819 — biophysics — Posted on 2022-05-23
1260 Cerebellum Directly Modulates the Substantia Nigra Dopaminergic Activity
Washburn, S.; Onate, M.; Yoshida, J.; Vera, J.; K.B., R.; Khatami, L.; Nadim, F.; Khodakhah, K.
10.1101/2022.05.20.492532 — neuroscience — Posted on 2022-05-22
1264 Biomolecular solution X-ray scattering at n2STAR Beamline
Gocenler, O.; Yenici, C. M.; Kahraman, K.; Buyukdag, C.; Dag, C.
10.1101/2022.05.20.492803 — biophysics — Posted on 2022-05-22
1268 Patterns of lineage-specific genome evolution in the brood parasitic black-headed duck (Heteronetta atricapilla)
Wuitchik, S. J.; Hillier, L. W.; Balakrishnan, C. J.; Sorenson, M. D.; Warren, W. C.; Sackton, T. B.
10.1101/2022.05.22.492970 — evolutionary biology — Posted on 2022-05-22
1272 Metabolic-imaging of human glioblastoma explants: a new precision-medicine model to predict tumor treatment response early
Morelli, M.; Lessi, F.; Barachini, S.; Liotti, R.; Montemurro, N.; Perrini, P.; Santonocito, O. S.; Gambacciani, C.; Snuderl, M.; Pieri, F.; Aquila, F.; Farnesi, A.; Naccarato, A. G.; Viacava, P.; Cardarelli, F.; Ferri, G.; Mulholland, P.; Ottaviani, D.; Paiar, F.; Liberti, G.; Pasqualetti, F.; Menicagli, M.; Aretini, P.; Signore, G.; Franceschi, S.; Mazzanti, C. M.
10.1101/2022.04.12.487679 — molecular biology — Posted on 2022-05-22
1273 Mice regulate their attentional intensity and arousal to exploit increases in task utility
de Gee, J. W.; Mridha, Z.; Hudson, M.; Shi, Y.; Ramsaywak, H.; Smith, S.; Karediya, N.; Thompson, M.; Jaspe, K.; Zhang, W.; McGinley, M. J.
10.1101/2022.03.04.482962 — neuroscience — Posted on 2022-05-22
1274 Minimally invasive delivery of peptides to the spinal cord for behavior modulation
Gao, Z.; David, E. T.; Leong, T. W.; Li, X.; Cai, Q.; Mwirigi, J. M.; Giannotta, M.; Dejana, E.; Wiggins, J.; Krishnagiri, S. P.; Bachoo, R. M.; Price, T. J.; Qin, Z.
10.1101/2022.05.20.492752 — neuroscience — Posted on 2022-05-22
1275 A therapeutically targetable NOTCH1-SIRT1-KAT7 axis in T-cell Leukemia
Lancho, O.; Singh, A.; da Silva-Diz, V.; Tottone, L.; Renck Nunes, P.; Aleksandrova, M.; Khatun, J.; Luo, S.; Zhao, C.; Zheng, H.; Chiles, E.; Zuo, Z.; Rocha, P. P.; Su, X.; Khiabanian, H.; Herranz, D.
10.1101/2022.05.21.492944 — cancer biology — Posted on 2022-05-22
1278 ExplaiNN: interpretable and transparent neural networks for genomics
Novakovsky, G.; Fornes, O.; Saraswat, M.; Mostafavi, S.; Wasserman, W. W.
10.1101/2022.05.20.492818 — genomics — Posted on 2022-05-22
1283 Differential excretory/secretory proteome of the adult female and male stages of the human blood fluke, Schistosoma mansoni
Kenney, E. T.; Mann, V. H.; Tanno, W. I.; Rosa, B. A.; Mitreva, M.; Bracken, B. K.; Loukas, A.; Brindley, P. J.; Sotillo, J.
10.1101/2022.05.22.492965 — microbiology — Posted on 2022-05-22
1287 Targeting acetyl-CoA metabolism attenuates the formation of fear memories through reduced activity-dependent histone acetylation
Alexander, D. C.; Corman, T.; Mendoza, M.; Glass, A.; Belity, T.; Campbell, R. R.; Han, J.; Keiser, A. A.; Winkler, J.; Wood, M. A.; Garcia, B. A.; Cohen, H.; Mews, P.; Egervari, G.; Berger, S. L.
10.1101/2022.05.22.492937 — neuroscience — Posted on 2022-05-22
1288 A global atlas of substrate specificities for the human serine/threonine kinome
Johnson, J. L.; Yaron, T. M.; Huntsman, E. M.; Kerelsky, A.; Song, J.; Regev, A.; Lin, T.-Y.; Liberatore, K.; Cizin, D. M.; Cohen, B. M.; Vasan, N.; Ma, Y.; Krismer, K.; Torres Robles, J.; van de Kooij, B.; van Vlimmeren, A. E.; Andree-Busch, N.; Käufer, N. F.; Dorovkov, M. V.; Ryazanov, A. G.; Takagi, Y.; Kastenhuber, E. R.; Goncalves, M. D.; Elemento, O.; Taatjes, D. J.; Maucuer, A.; Yamashita, A.; Degterev, A.; Blenis, J.; Hornbeck, P. V.; Turk, B. E.; Yaffe, M. B.; Cantley, L. C.
10.1101/2022.05.22.492882 — systems biology — Posted on 2022-05-22
1295 Spurious intragenic transcription is a hallmark of mammalian cellular senescence and tissue aging
Sen, P.; Donahue, G.; Li, C.; Lan, Y.; Egervari, G.; Robertson, N.; Shah, P. P.; Kerkhoven, E.; Schultz, D. C.; Adams, P. D.; Berger, S. L.
10.1101/2022.05.20.492816 — genomics — Posted on 2022-05-22
1298 Immunoregulatory subtype of dermal lymphatic endothelial cells at capillary terminals drives lymphatic malformations
Petkova, M.; Kraft, M.; Stritt, S.; Martinez-Corral, I.; Ortsater, H.; Sun, Y.; Vanlandewijck, M.; Jakic, B.; Baselga, E.; Castillo, S. D.; Graupera, M.; Betsholtz, C.; Makinen, T.
10.1101/2022.05.22.492950 — cell biology — Posted on 2022-05-22
1300 DEGRONOPEDIA - a web server for proteome-wide inspection of degrons
Szulc, N. A.; Stefaniak, F.; Piechota, M.; Cappannini, A.; Bujnicki, J. M.; Pokrzywa, W.
10.1101/2022.05.19.492622 — bioinformatics — Posted on 2022-05-22
1305 Inhibitory interneurons within the deep dorsal horn integrate convergent sensory input to regulate motor performance
Ozeri-Engelhard, N.; Gradwell, M. A.; Laflamme, O. D.; Upadhyay, A.; Aoki, A.; Shrier, T.; Gandhi, M.; Gonzalez, M.; Eisdorfer, J. T.; Abbas- Zadeh, G.; Yusuf, N.; Katz, J.; Haas, M.; Akay, T.; Abraira, V. E.
10.1101/2022.05.21.492933 — neuroscience — Posted on 2022-05-21
1306 Ecological Dynamics Imposes Fundamental Challenges in Microbial Source Tracking
Wang, X.-W.; Wu, L.; Dai, L.; Ying, X.; Zhang, T.; Weiss, S.; Liu, Y.-Y.
10.1101/2022.05.21.492809 — microbiology — Posted on 2022-05-21
1307 Two therapeutic CRISPR/Cas9 gene editing approaches revert FTD/ALS cellular pathology caused by a C9orf72 repeat expansion mutation in patient derived cells
Sckaff, M.; Gill, K.; Sachdev, A.; Birk, A. M.; Aladesuyi Arogundade, O.; Watry, H. L.; Keough, K. C.; Tsai, Y.-C.; Ziegle, J.; Conklin, B. R.; Clelland, C. D.
10.1101/2022.05.21.492887 — neuroscience — Posted on 2022-05-21
1308 Breathing dysfunction and alveolar damage in a mouse model of Dravet syndrome
Goh, M.-J.; Deering-Rice, C. E.; Nguyen, J.; Duyvesteyn, E.; Venosa, A.; Reilly, C. A.; Metcalf, C. S.
10.1101/2022.05.20.492889 — physiology — Posted on 2022-05-21
1309 Lactational delivery of Triclosan promotes non-alcoholic fatty liver disease in newborn mice
Weber, A.; Yang, X.; Mennillo, E.; Ding, J.; Watrous, J.; Jain, M.; Chen, S.-J.; Karin, M.; Tukey, R.
10.1101/2022.05.20.492880 — pharmacology and toxicology — Posted on 2022-05-21
1311 Chromosome-scale assembly of the lablab genome - A model for inclusive orphan crop genomics
Njaci, I.; Waweru, B.; Kamal, N.; Muktar, M. S.; Fisher, D.; Gundlach, H.; Muli, C.; Muthui, L.; Maranga, M.; Kiambi, D.; Maass, B. L.; Emmrich, P. M.; Entfellner, J.-B. D.; Spannagl, M.; Chapman, M. A.; Shorinola, O.; Jones, C. S.
10.1101/2022.05.08.491073 — genomics — Posted on 2022-05-21
1312 S. cerevisiae cells can grow without the Pds5 cohesin subunit
Choudhary, K.; Itzkovich, Z.; Alonso-Perez, E.; Bishara, H.; Dunn, B.; Sherlock, G.; Kupiec, M.
10.1101/2022.05.21.492904 — genetics — Posted on 2022-05-21
1313 Visinity: Visual Spatial Neighborhood Analysis for Multiplexed Tissue Imaging Data
Warchol, S.; Krueger, R.; Nirmal, A. J.; Gaglia, G.; Jessup, J.; Ritch, C. C.; Hoffer, J.; Muhlich, J. L.; Burger, M.; Jacks, T. L.; Santagata, S.; Sorger, P. K.; Pfister, H.
10.1101/2022.05.09.490039 — cell biology — Posted on 2022-05-21
1314 UHMK1 is a novel splicing regulatory kinase
Arfelli, V. C.; Chang, Y.-C.; Bagnoli, J. W.; Kerbs, P.; Ciamponi, F. E.; Paz, L. M. S.; Massirer, K. B.; Enard, W.; Kuster, B.; Greif, P. A.; Frohlich Archangelo, L.
10.1101/2022.05.21.492919 — molecular biology — Posted on 2022-05-21
1316 Purified cytosolic crystals from Bacillus thuringiensis as a novel active pharmaceutical ingredient (API)
Chicca, J.; Cazeault, N. R.; Rus, F.; Abraham, A.; Garceau, C.; Li, H.; Atwa, S. M.; Flanagan, K.; Soto, E.; Morrison, M. S.; Gazzola, D.; Hu, Y.; Liu, D. R.; Nielsen, M. K.; Urban, J. F.; Ostroff, G.; Aroian, R. V.
10.1101/2022.05.20.492900 — microbiology — Posted on 2022-05-21
1318 Integration of metabolism and regulation reveals rapid adaptability to growth on non-native substrates.
Trivedi, V. D.; Sullivan, S. F.; Choudhury, D.; Endalur Gopinarayanan, V.; Hart, T.; Nair, N. U.
10.1101/2022.05.21.492926 — synthetic biology — Posted on 2022-05-21
1319 Acute Vaping of a golden Syrian Hamster is Feasible and Leads to Nicotine-Dependent Respiratory Tract Inflammation
Hinds, D. M.; Nick, H. J.; Vallin, T. M.; Bloomquist, L. A.; Christeson, S.; Bratcher, P. E.; Cooper, E. H.; Brinton, J. T.; Bosco-Lauth, A.; White, C. W.
10.1101/2022.05.20.492852 — pharmacology and toxicology — Posted on 2022-05-21
1323 Probing the force-from-lipid mechanism with synthetic polymers
Jacobs, M. L.; Steinkühler, J.; Lemley, A.; Larmore, M. J.; Ng, L. C. T.; Cologna, S. M.; DeCaen, P. G.; Kamat, N.
10.1101/2022.05.20.492859 — biophysics — Posted on 2022-05-21
1325 A comprehensive assay of social motivation reveals sex-differential roles of ASC-associated genes and oxytocin
Maloney, S. E.; Sarafinovska, S.; Weichselbaum, C.; McCullough, K. B.; Swift, R. G.; Liu, Y.; Dougherty, J. D.
10.1101/2022.05.21.492918 — animal behavior and cognition — Posted on 2022-05-21
1328 Environmental DNA reveals invasive crayfish microbial associates and ecosystem-wide biodiversity before and after eradication
Ballare, K. M.; Worth, A.; Ruiz-Ramos, D. V.; Beraut, E.; Nava, H.; Fairbairn, C.; Wayne, R. K.; Shapiro, B.; Short, G.; Meyer, R. S.
10.1101/2022.05.20.492886 — ecology — Posted on 2022-05-21
1329 Nucleoli and the nucleoli-centromere association are dynamic during normal development and in cancer
Rodrigues, A.; MacQuarrie, K. L.; Freeman, E.; Willis, A. B.; Xu, Z.; Alvarez, A. A.; Ma, Y.; Perez White, B. E.; Foltz, D. R.; Huang, S.
10.1101/2022.05.21.492846 — cell biology — Posted on 2022-05-21
1330 Epitranscriptomic Modification of MicroRNA Increases Atherosclerosis Susceptibility
He, M.; Dong, J.; Zhang, Y.; Han, S. Y.; Wang, C.; Gongol, B.; Kang, J.; Huang, H.-Y.; Shyy, J. Y.-J.
10.1101/2022.05.21.492858 — molecular biology — Posted on 2022-05-21
1331 Butyrate differentiates permissiveness to Clostridioides difficile infection and influences growth of diverse C. difficile isolates
Pensinger, D.; Fisher, A. T.; Dobrila, H. A.; Van Treuren, W.; Gardner, J. O.; Higginbottom, S. K.; Carter, M. M.; Schumann, B.; Bertozzi, C.; Anikst, V.; Martin, C.; Robilotti, E.; Chow, J.; Buck, R. H.; Tompkins, L. S.; Sonnenburg, J. L.; Hryckowian, A. J.
10.1101/2022.05.20.492898 — microbiology — Posted on 2022-05-21
1332 Somatic hypermutation spectra are independent of the local transcriptional and epigenetic landscape
Schoeberl, U. E.; Fitz, J.; Froussios, K.; Valieris, R.; Makharova, M.; Ourailidis, I.; Bauer, B.; Neumann, T.; Wiedemann, E.-M.; Steininger, M.; Garcia, A. C.; Mastrovito, M.; Mouquet, H.; Silva, I.; Pavri, R.
10.1101/2022.05.21.492925 — immunology — Posted on 2022-05-21
1333 Transcriptome profiling of the ventral pallidum reveals a role for pallido-thalamic neurons in cocaine reward
Engeln, M.; Fox, M. E.; Chandra, R.; Choi, E. Y.; Nam, H.; Qadir, H.; Thomas, S. S.; Rhodes, V. M.; Turner, M. D.; Herman, R. J.; Calarco, C. A.; Lobo, M. K.
10.1101/2021.10.20.465105 — neuroscience — Posted on 2022-05-21
1335 Reward enhances memory via age-varying online and offline neural mechanisms across development
Cohen, A. O.; Glover, M. M.; Shen, X.; Phaneuf, C. V.; Avallone, K. N.; Davachi, L.; Hartley, C. A.
10.1101/2021.09.14.460286 — neuroscience — Posted on 2022-05-21
1338 High-throughput, real-time monitoring of engineered skeletal muscle function using magnetic sensing
Smith, A. S. T.; Luttrell, S. M.; Dupont, J.-B.; Gray, K.; Lih, D.; Fleming, J. W.; Cunningham, N. J.; Jepson, S.; Hesson, J.; Mathieu, J.; Maves, L.; Berry, B. J.; Fisher, E. C.; Sniadecki, N.; Geisse, N. A.; Mack, D. L.
10.1101/2022.05.20.492879 — bioengineering — Posted on 2022-05-21
1339 Robust alignment of single-cell and spatial transcriptomes with CytoSPACE
Vahid, M. R.; Brown, E. L.; Steen, C. B.; Kang, M.; Gentles, A. J.; Newman, A. M.
10.1101/2022.05.20.488356 — genomics — Posted on 2022-05-21
1341 Glial control of sphingolipid levels sculpts diurnal remodeling of circadian circuits
Vaughen, J.; Theisen, E.; Rivas-Serna, I. M.; Berger, A. B.; Anreiter, I.; Hartl, T.; Rodriguez, T.; Perlstein, E.; Mast, J.; Mazurak, V.; Reimer, R.; Clandinin, T.; Clandinin, T.
10.1101/2022.03.18.484007 — neuroscience — Posted on 2022-05-21
1342 Targeting BMP signaling mitigates osteoarthritis
Jaswal, A. P.; Kumar, B.; Roelofs, A. J.; Iqbal, S. F.; Singh, A. K.; Riemen, A. H. K.; Wang, H.; Sadaf, A.; Nanasaheb, S. V.; Agnihotri, N.; De Bari, C.; Bandyopadhyay, A.
10.1101/2021.03.01.433366 — pathology — Posted on 2022-05-21
1343 Cerebellum Directly Modulates the Substantia Nigra Dopaminergic Activity
Washborn, S.; Nadim, F.; Onate, M.; Vera, J.; Yoshida, J.; K.B., R.; Khatami, L.; Khodakhah, K.
10.1101/2022.05.20.492532 — neuroscience — Posted on 2022-05-21
1345 Hematopoietic stem cells are a long-term reservoir for trained immunity in a mouse model of chronic autoimmune disease
Mills, T. S.; Kain, B.; Burchill, M. T.; Danis, E.; Goodspeed, A.; Culp-Hill, R.; Ferrara, S.; Roede, J. R.; D'Alessandro, A.; King, K. Y.; Pietras, E. M.
10.1101/2022.05.20.492533 — immunology — Posted on 2022-05-21
1350 Determination of heavy metals in blood of nesting Kemps Ridley turtles ( Lepidochelys kempii ) at Rancho Nuevo sanctuary, Tamaulipas, Mexico.
Zavala-Felix, K. A.; Reyes-Lopez, M. A.; Camacho-Sanchez, F. Y.; Acosta-Sanchez, H. H.; Hart, C. E.; Leal-Sepulveda, V.; Espinoza-Romo, B. A.; Leal-Moreno, R.; Zavala-Norzagaray, A. A.; Aguirre, A. A.; Ley-Quinonez, C. P.
10.1101/2022.05.20.492828 — zoology — Posted on 2022-05-21
1351 Circadian and diel regulation of photosynthesis in the bryophyte Marchantia polymorpha
Cuitun-Coronado, D.; Rees, H.; Colmer, J.; Hall, A.; de Barros Dantas, L. L.; Dodd, A. N.
10.1101/2022.01.11.475783 — plant biology — Posted on 2022-05-20
1353 FoxA1 and FoxA2 regulate growth and cellular identity in NKX2-1-positive lung adenocarcinoma
Orstad, G.; Fort, G.; Parnell, T. J.; Jones, A.; Stubben, C.; Lohman, B.; Gillis, K. L.; Orellana, W.; Tariq, R.; Klingbeil, O.; Kaestner, K. H.; Vakoc, C.; Spike, B. T.; Snyder, E. L.
10.1101/2021.06.29.450247 — cancer biology — Posted on 2022-05-20
1355 AGS3 antagonizes LGN to balance oriented cell divisions and cell fate choices in mammalian epidermis
Descovich, C. P.; Lough, K. J.; Jena, A.; Wu, J. J.; Yom, J.; Spitzer, D. C.; Uppalapati, M.; Kedziora, K. M.; Williams, S. E.
10.1101/2022.05.20.492864 — developmental biology — Posted on 2022-05-20
1356 Lysogenized phages of methanotrophic bacteria show a broad and untapped genetic diversity
Stahn, M.; Grigonyte, A.; Orata, F. D.; Collins, D. A.; Rieder, L.; Kalyuzhnaya, M. G.; Millard, A. D.; Stein, L. Y.; Sauvageau, D.
10.1101/2022.05.20.492862 — microbiology — Posted on 2022-05-21
1358 Mechanoreceptor signal convergence and transformation in the dorsal horn flexibly shape a diversity of outputs to the brain
Chirila, A. M.; Rankin, G.; Tseng, S.-Y.; Emanuel, A.; Chavez-Martinez, C. L.; Zhang, D.; Harvey, C. D.; Ginty, D. D.
10.1101/2022.05.20.492853 — neuroscience — Posted on 2022-05-20
1359 The Adaptor Protein 2 (AP2) complex modulates habituation and behavioral selection across multiple pathways and time windows
Zuniga Mouret, R.; Greenbaum, J. P.; Doll, H. M.; Brody, E. M.; Iacobucci, E. L.; Roland, N. C.; Simamora, R. C.; Ruiz, I.; Seymour, R.; Ludwick, L.; Groneberg, A. H.; Marques, J. C.; Laborde, A.; Rajan, G.; Del Bene, F.; Orger, M. B.; Jain, R. A.
10.1101/2022.05.20.492863 — neuroscience — Posted on 2022-05-20
1360 A Remarkable Adaptive Paradigm Of Heart Performance And Protection Emerges In Response To The Constitutive Challenge Of Marked Cardiac-Specific Overexpression Of Adenylyl Cyclase Type 8
Tarasov, K. V.; Chakir, K.; Riordon, D. R.; Lyashkov, A. E.; Ahmet, I.; Perino, M. G.; Silvester, A. J.; Zhang, J.; Wang, M.; Lukyanenko, Y. O.; Qu, J.-H.; Barrera, M. C.-R.; Juhaszova, M.; Tarasova, Y. S.; Ziman, B.; Telljohann, R.; Kumar, V.; Ranek, M.; Lammons, J.; Beshkov, R.; deCabo, R.; Jun, S.; Keceli, G.; Gupta, A.; Yang, D.; Aon, M. A.; Adamo, L.; Morrell, C. H.; Otu, W.; Carroll, C.; Chambers, S.; Paolocci, N.; Huynh, T.; Pacak, K.; Weiss, R.; Field, L.; Sollott, S. S.; Lakatta, E. G.
10.1101/2022.05.20.491883 — physiology — Posted on 2022-05-20
1361 A Mesenchymal Cell Niche in Skin for Acute Myeloid Leukemia
Sandhow, L.; Cai, H.; Xiao, P.; Leonard, E.; Kondo, M.; Sun, X.; Johansson, A.-S.; Tryggvason, K.; Kasper, M.; Jaras, M.; QIAN, H.
10.1101/2022.05.20.491183 — cancer biology — Posted on 2022-05-20
1363 Systematic Analysis of Mobile Genetic Elements Mediating β-lactamase Gene Amplification in Non-Carbapenemase-Producing Carbapenem Resistant Enterobacterales Bloodstream Infections
Shropshire, W. C.; Konovalova, A.; McDaneld, P. M.; Gohel, M. H.; Strope, B. S.; Sahasrabhojane, P. V.; Tran, C. N.; Greenberg, D.; Kim, J.; Zhan, X.; Aitken, S.; Bhatti, M. M.; Savidge, T. C.; Treangen, T.; Hanson, B.; Arias, C. A.; Shelburne, S. A.
10.1101/2022.05.20.492874 — genomics — Posted on 2022-05-20
1364 Emergent coexistence in multispecies microbial communities
Chang, C.-Y.; Bajic, D.; Vila, J. C. C.; Estrela, S.; Sanchez, A.
10.1101/2022.05.20.492860 — ecology — Posted on 2022-05-20
1365 Septin-Mediated RhoA Activation Engages the Exocyst Complex to Recruit the Cilium Transition Zone
Safavian, D.; Kim, M. K.; Xie, H.; Dai, L.; Collins, R. F.; Froese, C.; Nagata, K.-i.; Trimble, W. S.
10.1101/2022.05.20.492811 — cell biology — Posted on 2022-05-20
1367 The organization of the gravity-sensing system in zebrafish
Liu, Z.; Hildebrand, D. G. C.; Morgan, J. L.; Jia, Y.; Slimmon, N.; Bagnall, M. W.
10.1101/2021.07.09.451839 — neuroscience — Posted on 2022-05-20
1369 Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms
Hall, S. R.; Rasmussen, S. A.; Crittenden, E.; Dawson, C. A.; Bartlett, K. E.; Westhorpe, A. P.; Albulescu, L.-O.; Kool, J.; Gutierrez, J. M.; Casewell, N. R.
10.1101/2022.05.20.492855 — pharmacology and toxicology — Posted on 2022-05-20
1370 PGC1β and ERRα promote glutamine metabolism and colorectal cancer survival via transcriptional regulation of PCK2
Fisher, K. W. W.; Frodyma, D.; Troia, T.; Berg, J. A.; Lewis, R. E.; Rao, C.; Svoboda, R.; Thomas, V.; Shinde, D.
10.1101/2022.05.20.492006 — cancer biology — Posted on 2022-05-20
1372 Humanized CAR T cells targeting p95HER2
Roman, M.; Rius Ruiz, I.; Grinyo-Escuer, A.; Duro-Sanchez, S.; Escorihuela, M.; Moessner, E.; Klein, C.; Arribas, J.
10.1101/2022.05.20.492812 — cancer biology — Posted on 2022-05-20
1373 Epigenetic plasticity via adaptive DNA hypermethylation and clonal expansion underlie resistance to oncogenic pathway inhibition in pancreatic cancer
Godfrey, L. K.; Forster, J.; Liffers, S.-T.; Schroeder, C.; Koester, J.; Henschel, L.; Ludwig, K. U.; Trajkovic-Arsic, M.; Behrens, D.; Scarpa, A.; Lawlor, R. T.; Witzke, K. E.; Sitek, B.; Johnsen, S. A.; Rahmann, S.; Horsthemke, B.; Zeschnigk, M.; Siveke, J. T.
10.1101/2022.05.20.492826 — cancer biology — Posted on 2022-05-20
1375 Ratiometric NAD+ sensors reveal subcellular NAD+ modulators
Chen, L.; Chen, M.; Luo, M.; Li, Y.; Liao, B.; Hu, M.; Yu, Q.
10.1101/2022.05.20.491061 — bioengineering — Posted on 2022-05-20
1376 Design of a mucin-selective protease for targeted degradation of cancer-associated mucins
Pedram, K.; Shon, D. J.; Tender, G. S.; Mantuano, N. R.; Northey, J. J.; Metcalf, K. J.; Wisnovsky, S. P.; Riley, N. M.; Forcina, G. C.; Malaker, S. A.; Kuo, A.; George, B. M.; Miller, C. L.; Casey, K. M.; Vilches-Moure, J. G.; Weaver, V. M.; Laubli, H.; Bertozzi, C. R.
10.1101/2022.05.20.492748 — biochemistry — Posted on 2022-05-20
1380 An apical protein, Pcr2, is required for persistent movement by the human parasite Toxoplasma gondii
Lopez, J. M.; Tengganu, I. F.; Liu, J.; Murray, J. M.; Arias Padilla, L. F.; Zhang, Y.; Florens, L.; Hu, K.
10.1101/2022.05.20.492694 — cell biology — Posted on 2022-05-20
1381 Cell survival enabled by leakage of a labile metabolic intermediate
Medina-Carmona, E.; Gutierrez-Rus, L. I.; Mannsour-Triedo, F.; Newton, M. S.; Gamiz-Arco, G.; Mota, A. J.; Reine, P.; Cuerva, J. M.; Ortega-Munoz, M.; Andres-Leon, E.; Ortega-Roldan, J. L.; Seelig, B.; Ibarra-Molero, B.; Sanchez-Ruiz, J.
10.1101/2022.05.20.492833 — molecular biology — Posted on 2022-05-20
1390 Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1
Leandro, J.; Khamrui, S.; Suebsuwong, C.; Chen, P.-J.; Secor, C.; Dodatko, T.; Yu, C.; Sanchez, R.; DeVita, R.; Houten, S.; Lazarus, M.
10.1101/2022.05.20.492856 — biochemistry — Posted on 2022-05-20
1391 CEP162 deficiency causes human retinal degeneration and reveals a dual role inciliogenesis and neurogenesis
Nuzhat, N.; Van Schil, K.; Liakopoulos, S.; Bauwens, M.; Duenas Rey, A.; Käseberg, S.; Jäger, M.; Willer, J. R.; Winter, J.; Truong, H.; Gruartmoner, N.; Van Heetvelde, M.; Wolf, J.; Merget, R.; Grasshoff-Derr, S.; Van Dorpe, J.; Hoorens, A.; Stöhr, H.; Mansard, L.; Roux, A.-F.; Langmann, T.; Dannhausen, K.; Rosenkranz, D.; Wissing, K. M.; Van Lint, M.; Rossmann, H.; Häuser, F.; Nürnberg, P.; Thiele, H.; Zechner, U.; Pearring, J. N.; De Baere, E.; Bolz, H. J.
10.1101/2021.11.23.469779 — genetics — Posted on 2022-05-20
1393 High Concentrations of floating life in the North Pacific Garbage Patch
Chong, F.; Spencer, M.; Maximenko, N.; Hafner, J.; McWhirter, A.; Helm, R. R.
10.1101/2022.04.26.489631 — ecology — Posted on 2022-05-20
1394 wrmXpress: A modular package for high-throughput image analysis of parasitic and free-living worms
Wheeler, N. J.; Gallo, K. J.; Garncarz, E. J.; Ryan, K. T.; Chan, J. D.; Zamanian, M.
10.1101/2022.05.18.492482 — microbiology — Posted on 2022-05-20
1395 Cooperative binding of TCR and CD4 to pMHC enhances TCR sensitivity
Rushdi, M. N.; Pan, V.; Li, K.; Travaglino, S.; Choi, H.-K.; Hong, J.; Griffitts, F.; Agnihotri, P.; Mariuzza, R. A.; Ke, Y.; Zhu, C.
10.1101/2021.11.22.469547 — immunology — Posted on 2022-05-20
1396 Age-related response speed deficits arise from specific impairments in sensory evidence accumulation rate
Brosnan, M. B.; O'Neill, M. H.; Loughnane, G. M.; Pearce, D. J.; Fleming, B.; Chong, T. T. J.; Nobre, A. C.; O'Connell, R. G.; Bellgrove, M. A.
10.1101/2021.10.28.466233 — neuroscience — Posted on 2022-05-20
1400 Microbial Nanocellulose Biotextiles for a Circular Materials Economy
Schiros, T. N.; Antrobus, R.; Farias, D.; Chiu, Y.-T.; Joseph, C. T.; Esdaille, S.; Sanchiricco, G. K.; Miquelon, G.; An, D.; Russell, S. T.; Chitu, A.; Goetz, S.; Chasse, A. M. V.; Nuckolls, C.; Kumar, S. K.; Lu, H. H.
10.1101/2021.09.22.461422 — bioengineering — Posted on 2022-05-20
1405 Omicron breakthrough infections in vaccinated or previously infected hamsters
Zhou, J.; Sukhova, K.; McKay, P. F.; Kurshan, A.; Yau, Y.; Lechmere, T.; Brown, J. C.; Moshe, M.; Kugathasan, R.; Snell, L. B.; Edgeworth, J. D.; Shattock, R. J.; Doores, K. J.; Peacock, T. P.; Barclay, W. S.
10.1101/2022.05.20.492779 — microbiology — Posted on 2022-05-20
1406 Molecular, circuit, and stress response characterization of Ventral Pallidum Npas1-neurons
Morais-Silva, G.; Nam, H.; Campbell, R. R.; Basu, M.; Pagliusi, M.; Fox, M. E.; Chan, S.; Iniguez, S. D.; Ament, S. A.; Marin, M. T.; Lobo, M. K.
10.1101/2021.10.27.466188 — neuroscience — Posted on 2022-05-20
1407 Structural basis for substrate selection by the SARS-CoV-2 replicase
Malone, B. F.; Perry, J. K.; Olinares, P. D. B.; Chen, J.; Appleby, T. K.; Feng, J. Y.; Bilello, J. P.; Ng, H.; Sotiris, J.; Ebrahim, M.; Chua, E. Y. D.; Mendez, J. H.; Eng, E. T.; Landick, R.; Chait, B. T.; Campbell, E. A.; Darst, S. A.
10.1101/2022.05.20.492815 — biophysics — Posted on 2022-05-20
1408 The spike-stabilizing D614G mutation interacts with S1/S2 cleavage site mutations to promote the infectious potential of SARS-CoV-2 variants
Gellenoncourt, S.; Saunders, N.; Robinot, R.; Auguste, L.; Rajah, M. M.; Kervevan, J.; Jeger-Madiot, R.; Staropoli, I.; Planchais, C.; Mouquet, H.; Buchrieser, J.; Schwartz, O.; Chakrabarti, L. A.
10.1101/2022.05.20.492832 — microbiology — Posted on 2022-05-20
1409 Deep mutational scanning identifies SARS-CoV-2 Nucleocapsid escape mutations of currently available rapid antigen tests
Frank, F.; Keen, M. M.; Rao, A.; Bassit, L.; Liu, X.; Bowers, H. B.; Patel, A. B.; Cato, M. L.; Sullivan, J. A.; Greenleaf, M.; Piantadosi, A.; Lam, W.; Hudson, W.; Ortlund, E. A.
10.1101/2022.05.19.492641 — immunology — Posted on 2022-05-20
1410 SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly
Onnis, A.; Andreano, E.; Cassioli, C.; Pantano, E.; Abbiento, V.; Marotta, G.; Rappuoli, R.; Baldari, C. T.
10.1101/2022.05.20.492764 — immunology — Posted on 2022-05-20
1412 Revealing druggable cryptic pockets in the Nsp-1 of SARS-CoV-2 and other β-coronaviruses by simulations and crystallography
Borsatto, A.; Galdadas, I.; Gervasio, F. L.; Estarellas, C.; Haider, S.; Kozielski, F.; Damfo, S.; Ma, S.
10.1101/2022.05.20.492819 — biophysics — Posted on 2022-05-20
1413 Rab11 regulates autophagy at dendritic spines in an mTOR- and NMDA-dependent manner
Janusz-Kaminska, A. M.; Brzozowska, A.; Tempes, A.; Urbanska, M.; Blazejczyk, M.; Milek, J. M.; Zeng, J.; Kisielewska, K.; Jaworski, J.
10.1101/2022.05.20.492668 — neuroscience — Posted on 2022-05-20
1414 Global predictions for the risk of establishment of Pierce's disease of grapevines
Gimenez-Romero, A.; Galvan, J.; Montesinos, M.; Bauza, J.; Godefroid, M.; Fereres, A.; Ramasco, J. J.; Matias, M. A.; Moralejo, E.
10.1101/2022.05.20.492796 — plant biology — Posted on 2022-05-20
1416 Comparative and systems analyses of Leishmania spp. non-coding RNAs through developmental stages
Martinez-Hernandez, J. E.; Aliaga-Tobar, V.; Gonzalez, C.; Monte-Neto, R.; Martin, A. J. M.; Maracaja-Coutinho, V.
10.1101/2021.05.17.444077 — genomics — Posted on 2022-05-20
1420 CRISPR-Cas provides limited phage immunity to a prevalent gut bacterium in gnotobiotic mice
Rasmussen, T. S.; Koefoed, A. K.; Deng, L.; Muhammed, M. K.; Rousseau, G. M.; Kot, W. P.; Sprotte, S.; Neve, H.; Franz, C. M. A. P.; Hansen, A. K.; Vogensen, F. K.; Moineau, S.; Nielsen, D. S.
10.1101/2022.05.20.492479 — microbiology — Posted on 2022-05-20
1422 A Distributed Network for Multimodal Experiential Representation of Concepts
Tong, J.-Q.; Binder, J. R.; Humphries, C. J.; Mazurchuk, S.; Conant, L. L.; Fernandino, L.
10.1101/2021.07.05.451188 — neuroscience — Posted on 2022-05-20
1423 The proportional recovery rule redux: Arguments for its biological and predictive relevance
Goldsmith, J.; Kitago, T.; Garcia de la Garza, A.; Kundert, R.; Luft, A.; Stinear, C. M.; Byblow, W. D.; Kwakkel, G.; Krakauer, J. W.
10.1101/2021.05.20.445022 — neuroscience — Posted on 2022-05-20
1425 Ephemeral Resource Availability Makes Wild Guppies More Social
Snijders, L.; Krause, S.; Novaes Tump, A.; Breuker, M.; Ramnarine, I. W.; Kurvers, R. H.; Krause, J.
10.1101/2022.05.20.492799 — animal behavior and cognition — Posted on 2022-05-20
1426 APOE Expression and Secretion are Modulated by Copper-Dependent and -Independent Mitochondrial Dysfunction
Wynne, M. E.; Ogunbona, O.; Lane, A. R.; Gokhale, A.; Zlatic, S. A.; Xu, C.; Wen, Z.; Duong, D.; Rayaprolu, S.; Ivanova, A.; Ortlund, E. A.; Seyfried, N. T.; Crocker, A.; Shanbhag, V.; Petris, M.; Senoo, N.; Kandasamy, S.; Claypool, S. M.; Wingo, A. P.; Wingo, T. S.; Rangaraju, S.; Levey, A.; Werner, E.; Faundez, V.
10.1101/2022.05.11.491499 — cell biology — Posted on 2022-05-20
1427 Highly divergent white-tailed deer SARS-CoV-2 with potential deer-to-human transmission
Pickering, B.; Lung, O.; Maguire, F.; Kruczkiewicz, P.; Kotwa, J. D.; Buchanan, T.; Gagnier, M.; Guthrie, J.; Jardine, C.; Marchand-Austin, A.; Masse, A.; McClinchey, H.; Nirmalarajah, K.; Aftanas, P.; Blais-Savoie, J.; Chee, H.-Y.; Chien, E.; Yim, W.; Banete, A.; Griffin, B. D.; Yip, L.; Goolia, M.; Suderman, M.; Pinette, M.; Smith, G.; Sullivan, D.; Rudar, J.; Adey, E.; Nebroski, M.; Goyette, G.; Finzi, A.; Laroche, G.; Ariana, A.; Vahkal, B.; Cote, M.; McGeer, A.; Nituch, L.; Mubareka, S.; Bowman, J.
10.1101/2022.02.22.481551 — microbiology — Posted on 2022-05-20
1429 The Batten disease protein CLN3 is important for stress granules dynamics and translational activity.
Relton, E.; Roth, N. J.; Yasa, S.; Kaleem, A.; Hermey, G.; Lefrancois, S.; McCormick, P.; Locker, N.
10.1101/2022.05.20.492784 — molecular biology — Posted on 2022-05-20
1430 Structure of nucleosome-bound human PBAF complex
Wang, L.; Yu, J.; Yu, Z.; Wang, Q.; Li, W.; Ren, Y.; Chen, Z.; He, S.; Xu, Y.
10.1101/2022.05.20.492795 — molecular biology — Posted on 2022-05-20
1431 EZH2 interacts with MEG3 to directly regulate integrin signaling and endothelial cell function
Dudnakova, T.; Dunn-Davies, H.; Nogara, A.; Rodor, J.; Thomas, A.; Parish, E.; Gautier, P.; Meynert, A.; Madeddu, P.; Caporali, A.; Baker, A.; Tollervey, D.; Mitic, T.
10.1101/2022.05.20.492787 — molecular biology — Posted on 2022-05-20
1434 Evidence for different greater-persistence strategies under lower and higher challenge for alcohol in female rats
De Oliveira Sergio, T.; Darevsky, D.; de Paula Soares, V.; de Cassia Albino, M.; Maulucci, D.; Wean, S.; Hopf, F.
10.1101/2022.05.18.492488 — neuroscience — Posted on 2022-05-20
1438 Rab11 regulates autophagy at dendritic spines in an mTOR- and NMDA-dependent manner
Janusz-Kaminska, A. M.; Brzozowska, A.; Tempes, A.; Urbanska, M.; Blazejczyk, M.; Milek, J. M.; Zeng, J.; Kisielewska, K.; Jaworski, J.
10.1101/2022.05.20.492668 — neuroscience — Posted on 2022-05-20
1439 Minimally invasive delivery of peptides to the spinal cord for behavior modulation
Gao, Z.; David, E. T.; Leong, T. W.; Li, X.; Cai, Q.; Mwirigi, J. M.; Giannotta, M.; Dejana, E.; Wiggins, J.; Krishnagiri, S. P.; Bachoo, R. M.; Price, T. J.; Qin, Z.
10.1101/2022.05.20.492752 — neuroscience — Posted on 2022-05-20
1440 Single cell analysis of the dorsal V-SVZ reveals differential quiescence of postnatal pallial and subpallial neural stem cells driven by TGFbeta/BMP-signalling
Marcy, G.; Foucault, L.; Babina, E.; Texeraud, E.; Zweifel, S.; Heinrich, C.; Parras, C.; Vargas-Hernandez, H.; Jabaudon, D.; Raineteau, O.
10.1101/2022.05.20.492790 — neuroscience — Posted on 2022-05-20
1443 Rudimentary Structure-Activity-Relationship study of the MMV Pathogen Box compound MMV675968 (2,4-diaminoquinazoline) unveils novel inhibitors of Trypanosoma brucei brucei DHFR enzyme
Dize, D.; Tata, R.; Keumoe, R.; Kouipou, R. T.; Tchatat, M. B.; Njanpa, C.; Tchuenguia, V. C.; Tchokouaha, L. Y.; Fokou, P. V. T.; Laleu, B.; Duffy, J.; Bishop, O. T.; Boyom, F. F.
10.1101/2022.05.20.492762 — pharmacology and toxicology — Posted on 2022-05-20
1444 Interplay between VSD, pore and membrane lipids in electromechanical coupling in HCN channels
Elbahnsi, A.; Cowgill, J.; Burtscher, V.; Wedemann, L.; Zeckey, L.; Chanda, B.; Delemotte, L.
10.1101/2022.05.20.492765 — biophysics — Posted on 2022-05-20
1447 Succinylated lysine residue prediction revisited
Ahmed, S. S.; Rifat, Z. T.; Rahman, S.; Rahman, M. S.
10.1101/2022.05.20.492505 — bioinformatics — Posted on 2022-05-20
1450 Scalable power analysis and effect size exploration of microbiome community differences with Evident
Rahman, G.; McDonald, D.; Gonzalez, A.; Vazquez-Baeza, Y.; Jiang, L.; Casals-Pascual, C.; Peddada, S.; Hakim, D.; Dilmore, A. H.; Nowinski, B.; Knight, R.
10.1101/2022.05.19.492684 — bioinformatics — Posted on 2022-05-20
1451 recountmethylation enables flexible analysis ofpublic blood DNA methylation array data
Maden, S. K.; Walsh, B.; Ellrott, K.; Hansen, K. D.; Thompson, R.; Nellore, A.
10.1101/2022.05.19.492680 — bioinformatics — Posted on 2022-05-20
1452 Automated optimisation of solubility and conformational stability of antibodies and proteins
Rosace, A.; Bennett, A.; Oeller, M.; Mortensen, M. M.; Sakhnini, L. I.; Sormanni, P.
10.1101/2022.05.20.492798 — biochemistry — Posted on 2022-05-20
1455 Molecular Phylogenetics of HIV-1 Subtypes in African Populations: A Case Study of Sub-Saharan African Countries
Obura, H. O.; Mlay, C. D.; Moyo, L.; Karumbo, B. M.; Omar, K. M.; Sinza, E. M.; Rotich, G. J.; Mudaki, W.; Kamau, B. M.; Awe, O. I.
10.1101/2022.05.18.492401 — genomics — Posted on 2022-05-20
1456 Metabolic, Fibrotic, and Splicing Pathways Are All Altered in Emery-Dreifuss Muscular Dystrophy Spectrum Patients to Differing Degrees
de las Heras, J. I.; Todorow, V.; Krecinic-Balic, L.; Hintze, S.; Czapiewski, R.; Webb, S.; Schoser, B.; Meinke, P.; Schirmer, E. C.
10.1101/2022.05.20.492778 — genetics — Posted on 2022-05-20
1459 Semi-field and surveillance data define the natural diapause timeline for Culex pipiens across the United States
Field, E. N.; Shepard, J. J.; Clifton, M. E.; Price, K. J.; Witmier, B. J.; Johnson, K.; Boze, B.; Abadam, C.; Ebel, G. D.; Armstrong, P. M.; Barker, C. M.; Smith, R. C.
10.1101/2022.05.19.492729 — ecology — Posted on 2022-05-20
1464 Competition-cooperation in the chemoautotrophic ecosystem of Movile Cave - first metagenomic approach on sediments
Chiciudean, I.; Russo, G.; Bogdan, D. F.; Levei, E. A.; Faur, L.; Hillebrand-Voiculescu, A.; Moldovan, O. T.; Banciu, H. L.
10.1101/2022.05.19.492637 — microbiology — Posted on 2022-05-20
1467 The Queensland Twin Adolescent Brain Project, a longitudinal study of adolescent brain development
Strike, L. T.; Hansell, N. K.; Chuang, K.-H.; Miller, J. L.; de Zubicaray, G. I.; Thompson, P. M.; McMahon, K. L.; Wright, M. J.
10.1101/2022.05.19.492753 — neuroscience — Posted on 2022-05-20
1470 Gpr88 deletion impacts motivational control independently of striatal dopamine function
Spark, D. L.; Vermeulen, M. H.; Rueda, P.; Gonzalez, R. d. l. F.; Sepehrizadeh, T.; De Veer, M.; Mannoury la Cour, C.; Fornito, A.; Langiu, M.; Nithianantharajah, J.; Stewart, G. D.; Langmead, C. J.
10.1101/2022.05.19.492565 — neuroscience — Posted on 2022-05-20
1471 A single closed head injury in mice induces chronic, progressive white matter atrophy and increased phospho-tau expressing oligodendrocytes
Havlicek, D. F.; Furhang, R.; Nikulina, E.; Smith-Salzberg, B.; Lawless, S.; Severin, S. A.; Mallaboeva, S.; Nayab, F.; Seifert, A. C.; Crary, J. F.; Bergold, P.
10.1101/2022.05.19.492705 — neuroscience — Posted on 2022-05-20
1473 Accurate speech decoding requires high-resolution neural interfaces
Duraivel, S.; Rahimpour, S.; Chiang, C.-H.; Trumpis, M.; Wang, C.; Barth, K.; Lad, S. P.; Friedman, A. H.; Southwell, D. G.; Sinha, S. R.; Viventi, J.; Cogan, G. B.
10.1101/2022.05.19.492723 — neuroscience — Posted on 2022-05-20
1479 Temporal origin of mouse claustrum and development of its cortical projections
Hoerder-Suabedissen, A.; Ocana-Santero, G.; Draper, T. H.; Scott, S. A.; Kimani, J. G.; Shelton, A. M.; Butt, S. J.; Molnar, Z.; Packer, A. M.
10.1101/2022.05.20.492804 — neuroscience — Posted on 2022-05-20
1495 Isoform-specific O-glycosylation dictates Ebola virus infectivity
Bagdonaite, I.; Abdurahman, S.; Mirandola, M.; Frank, M.; Narimatsu, Y.; Vakhrushev, S. Y.; Salata, C.; Mirazimi, A.; Wandall, H. H.
10.1101/2022.04.25.489418 — microbiology — Posted on 2022-05-20
1496 APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge
Lee, S.; Devanney, N. A.; Golden, L. R.; Smith, C. T.; Schwartz, J. L.; Walsh, A. E.; Clarke, H. A.; Goulding, D. S.; Allenger, E. J.; Morillo-Segovia, G.; Friday, C. M.; Gorman, A. A.; Hawkinson, T. R.; MacLean, S. M.; Williams, H. C.; Sun, R. C.; Morganti, J. M.; Johnson, L. A.
10.1101/2022.05.17.492361 — neuroscience — Posted on 2022-05-20
1497 The NAD+ precursor NMN activates dSarm to trigger axon degeneration in Drosophila
Rosell, A. L.; Paglione, M.; Gilley, J.; Kocia, M.; Gasparrini, M.; Cialabrini, L.; Raffaelli, N.; Angeletti, C.; Orsomando, G.; Coleman, M.; Loreto, A.; Neukomm, L.
10.1101/2022.01.30.478002 — neuroscience — Posted on 2022-05-20
1500 Frontal cortex learns to add evidence across modalities
Coen, P.; Sit, T. P.; Wells, M. J.; Carandini, M.; Harris, K. D.
10.1101/2021.04.26.441250 — neuroscience — Posted on 2022-05-20
1503 Computationally designed GPCR quaternary structures bias signaling pathway activation
Paradis, J. S.; Feng, X.; Murat, B.; Jefferson, R. E.; Szpakowska, M. E.; Hogue, M.; Bergkamp, N. D.; Heidenreich, F. M.; Smit, M. J.; Chevigne, A.; Bouvier, M.; Barth, P.
10.1101/2021.09.23.461493 — biophysics — Posted on 2022-05-20
1504 Multisite Phosphorylation and Binding Alter Conformational Dynamics of the 4E-BP2 Protein
Smyth, S.; Zhang, Z.; Bah, A.; Tsangaris, T.; Dawson, J.; Forman-Kay, J. D.; Gradinaru, C.
10.1101/2022.01.14.476386 — biophysics — Posted on 2022-05-20
1507 Whole genome sequencing uncovers the structural and transcriptomic landscape of hexaploid wheat/Ambylopyrum muticum introgression lines
Coombes, B.; Fellers, J. P.; Grewal, S.; Rusholme-Pilcher, R.; Hubbart-Edwards, S.; Yang, C.-Y.; Joynson, R.; King, I. P.; King, J.; Hall, A.
10.1101/2021.11.16.468825 — genomics — Posted on 2022-05-20
1508 A chromosome-level genome assembly and annotation of a maize elite breeding line Dan340
Zhao, Y.; Wang, Y.; Ma, D.; Feng, G.; Huo, Y.; Liu, Z.; Zhou, L.; Zhang, Y.; Xu, L.; Wang, L.; Zhao, H.; Zhao, J.; Wang, F.
10.1101/2021.04.26.441299 — genomics — Posted on 2022-05-20
1509 ZDHHC5 targets Protocadherin 7 to the cell surface by a palmitoylation-dependent mechanism to promote successful cytokinesis
Ozkan-Kucuk, N. E.; Yigit, B. N.; Degirmenci, B. S.; Qureshi, M. H.; Kamacioglu, A.; Bavili, N.; Kiraz, A.; Ozlu, N.
10.1101/2020.05.24.111831 — cell biology — Posted on 2022-05-20
1510 Survivin prevents the Polycomb Repressor Complex 2 from methylating Histone 3 lysine 27
Jensen, M.; Garcia-Bonete, M.-J.; Anindya, A. L.; Andersson, K.; Erlandsson, M. C.; Oparina, N.; Brath, U.; Chandrasekaran, V.; Bokarewa, M.; Katona, G.
10.1101/2022.04.27.489567 — molecular biology — Posted on 2022-05-20
1511 Diverse innate immune factors protect yeast from lethal viral pathogenesis
Chau, S.; Gao, J.; Diao, A. J.; Cao, S. B.; Azhieh, A.; Davidson, A. R.; Meneghini, M. D.
10.1101/2022.02.14.480455 — microbiology — Posted on 2022-05-20
1512 Gliotransmission orchestrates neuronal type-specific axon regeneration
Wang, F.; Ruppell, K. T.; Zhou, S.; Qu, Y.; Shang, Y.; Gong, J.; Li, Y.; Xiang, Y.
10.1101/799635 — neuroscience — Posted on 2022-05-20
1513 Postsynaptic plasticity of cholinergic synapses underlies the induction and expression of appetitive memories in Drosophila
Pribbenow, C.; Chen, Y.-c.; Heim, M.-M.; Laber, D.; Reubold, S.; Reynolds, E.; Balles, I.; Suarez Grimalt, R.; Rauch, C.; Roesner, J.; Fernandez-d.V. Alquicira, T.; Owald, D.
10.1101/2021.07.01.450776 — neuroscience — Posted on 2022-05-20
1514 Spatial Transcriptomics-correlated Electron Microscopy
Androvic, P.; Schifferer, M.; Perez Anderson, K.; Cantuti-Castelvetri, L.; Ji, H.; Liu, L.; Besson-Girard, S.; Knoferle, J.; Simons, M.; Gokce, O.
10.1101/2022.05.18.492475 — neuroscience — Posted on 2022-05-20
1516 Impaired Epigenesis of Imprinting Predispositions Causes Autism-like Behavioral Phenotypes in Domestic Chicks
Matsushima, T.; Miura, M.; Patzke, N.; Toji, N.; Wada, K.; Ogura, Y.; Homma, K. J.; Sgado, P.; Vallortigara, G.
10.1101/2022.05.19.492744 — animal behavior and cognition — Posted on 2022-05-20
1523 Non-invasive vagus nerve stimulation in a hungry state decreases heart rate variability and wanting of a palatable drink
Altınkaya, Z.; Öztürk, L.; Büyükgüdük, I.; Yanık, H.; Yılmaz, D. D.; Yar, B.; Degirmenci, E.; Dal, U.; Veldhuizen, M. G.
10.1101/2022.05.18.492424 — neuroscience — Posted on 2022-05-20
1526 Periostin+ stromal cells guide lymphovascular invasion by cancer cells
Null, J. L.; Kim, D. J.; McCann, J. V.; Kumar, P.; Edatt, L.; Pecot, C. V.; Dudley, A. C.
10.1101/2022.05.19.492742 — cancer biology — Posted on 2022-05-20
1527 A "cooperative collaboration" between HAND2 and MYCN shapes neuroblastoma cell identity
Xu, M.; Sun, M.; Zhang, X.; Nguyen, R.; Lei, H.; Shern, J. F.; Thiele, C. J.; Liu, Z.
10.1101/2022.05.18.492511 — cancer biology — Posted on 2022-05-20
1529 Mechanosensor Piezo1 Mediates Bimodal Patterns of Intracellular Signaling
Pan, Y.; Shi, L. Z.; Preece, D.; Gomez-Godinez, V.; Yoon, C. W.; Lu, S.; Carmona, C.; Woo, S.-H.; Chien, S.; W. Berns, M.; Liu, L.; Wang, Y.
10.1101/2022.05.19.492730 — biophysics — Posted on 2022-05-20
1534 Spatially selective stimulation of the pig vagus nerve to modulate target effect versus side effect
Blanz, S. L.; Musselman, E. D.; Settell, M. L.; Knudsen, B. E.; Nicolai, E. N.; Trevathan, J. K.; Verner, R. S.; Begnaud, J.; Suminski, A. J.; Williams, J. C.; Shoffstall, A. J.; Grill, W. M.; Pelot, N. A.; Ludwig, K. A.
10.1101/2022.05.19.492726 — bioengineering — Posted on 2022-05-20
1535 A comparative study of structural variant calling strategies using the Alzheimer's Disease Sequencing Project's whole genome family data
Malamon, J. S.; Farrell, J. J.; Xia, L. C.; Dombroski, B. A.; Lee, W.-P.; Das, R. G.; Vardarajan, B. N.; Way, J.; Kuzma, A. B.; Valladares, O.; Leung, Y. Y.; Scanlon, A.; Lopez, I. A. B.; Brehony, J.; Worley, K. C.; Zhang, N. R.; Wang, L.-S.; Farrer, L. A.; Schellenberg, G. D.
10.1101/2022.05.19.492472 — genetics — Posted on 2022-05-20
1539 Exploring the mosquito-arbovirus network: a survey of vector competence experiments
Chen, B.; Sweeny, A.; Wu, V. Y.; Christofferson, R. C.; Ebel, G.; Fagre, A. C.; Gallichotte, E.; Kading, R.; Ryan, S. J.; Carlson, C. J.
10.1101/2022.05.19.492743 — ecology — Posted on 2022-05-20
1540 Scent mark signal investment predicts fight dynamics in house mice
Miller, C. H.; Haxhillari, K.; Hillock, M. F.; Reichard, T. M.; Sheehan, M. J.
10.1101/2022.05.19.492706 — ecology — Posted on 2022-05-20
1542 mNeonGreen-tagged fusion proteins and nanobodies reveal localization of tropomyosin to patches, cables, and contractile actomyosin rings in live yeast cells
Hatano, T.; Lim, T. C.; Billault-Chaumartin, I.; Dhar, A.; Gu, Y.; Massam-Wu, T.; Adhishesha, S.; Springall, L.; Scott, W.; Sivashanmugam, L.; Mishima, M.; Martin, S. G.; Oliferenko, S.; Palani, S.; BALASUBRAMANIAN, M. K.
10.1101/2022.05.19.492673 — cell biology — Posted on 2022-05-20
1546 Homeostatic changes maintain the gain control of spinal motoneurones across the lifetime of C57BL/6J mice
Goltash, S.; Jensen, M. H.; Dimintiyanova, K. P.; Jensen, D. B.; Lehnhoff, J.; Moldovan, M.; Meehan, C. F.
10.1101/2022.05.19.492717 — neuroscience — Posted on 2022-05-20
1554 The TERT promoter is polycomb-repressed in neuroblastoma cells with long telomeres
Graham, M. K.; Xu, B.; Davis, C.; Meeker, A. K.; Heaphy, C. M.; Yegnasubramanian, S.; Dyer, M. A.; Zeineldin, M.
10.1101/2022.05.18.492493 — cancer biology — Posted on 2022-05-20
1563 Impaired Epigenesis of Imprinting Predispositions Causes Autism-like Behavioral Phenotypes in Domestic Chicks
Matsushima, T.; Miura, M.; Patzke, N.; Toji, N.; Wada, K.; Ogura, Y.; Homma, K. J.; Sgado, P.; Vallortigara, G.
10.1101/2022.05.19.492744 — animal behavior and cognition — Posted on 2022-05-20
1567 Space-time home range estimates and resource selection for the Critically Endangered Philippine Eagle on Mindanao
Sutton, L. J.; Ibanez, J. C.; Salvador, D. I.; Taraya, R. L.; Opiso, G. S.; Senarillos, T. L. P.; McClure, C. J.
10.1101/2022.05.19.492630 — ecology — Posted on 2022-05-20
1570 Western diet-induced shifts in the maternal microbiome are associated with altered microRNA expression in baboon placenta and fetal liver
Sugino, K. Y.; Mandala, A.; Janssen, R. C.; Gurung, S.; Trammell, M.; Day, M. W.; Brush, R. S.; Papin, J. F.; Dyer, D. W.; Agbaga, M.-P.; Friedman, J. E.; Castillo-Castrejon, M.; Jonscher, K. R.; Myers, D. A.
10.1101/2022.05.18.492490 — developmental biology — Posted on 2022-05-20
1571 Sex-specific topological differences in germline cell lineage trees
Diegmiller, R.; Imran Alsous, J.; Li, D.; Yamashita, Y. M.; Shvartsman, S.
10.1101/2022.05.18.492500 — developmental biology — Posted on 2022-05-20
1572 Spatiotemporal dynamics of membrane surface charge regulates cell polarity and migration
Banerjee, T.; Biswas, D.; Pal, D. S.; Miao, Y.; Iglesias, P. A.; Devreotes, P. N.
10.1101/2022.05.19.492577 — cell biology — Posted on 2022-05-20
1573 Gene expression profiling reveals B cells are highly educated by the pancreatic environment during autoimmune diabetes
Boldison, J.; Hopkinson, J.; Davies, J.; Pearson, J.; Leete, P.; Richardson, S.; Morgan, N. G.; Wong, F. S.
10.1101/2022.05.19.492647 — immunology — Posted on 2022-05-20
1575 Spatiotemporal organization of human sensorimotor beta burst activity
Zich, C.; Quinn, A. J.; Bonaiuto, J. J.; O'Neill, G.; Mardell, L. C.; Ward, N. S.; Bestmann, S.
10.1101/2022.05.19.492617 — neuroscience — Posted on 2022-05-20
1577 AI-guided screen identifies probucol-mediated mitophagy enhancement through modulation of lipid droplets
Moskal, N.; Visanji, N. P.; Gorbenko, O.; Narasimhan, V.; Nash, J.; Lewis, P. N.; McQuibban, G. A.
10.1101/2022.05.18.492560 — neuroscience — Posted on 2022-05-20
1579 Effect of pressure insole sampling frequency on peak force accuracy during running
Elstub, L. J.; Grohowski, L. M.; Wolf, D. N.; Owen, M. K.; Noehren, B.; Zelik, K. E.
10.1101/2022.05.18.492523 — physiology — Posted on 2022-05-20
1581 Cell-to-cell variability of dynamic CXCL12-CXCR4 signaling and morphological processes in chemotaxis
Ho, K. K. Y.; Srivastava, S.; Kinnunen, P. C.; Garikipati, K.; Luker, G. D.; Luker, K. E.
10.1101/2022.05.19.492090 — cancer biology — Posted on 2022-05-20
1583 Resolution doubling in light-sheet microscopy via oblique plane structured illumination
Chen, B.; Chang, B.-J.; Roudot, P.; Zhou, F.; Sapoznik, E.; Marlar-Pavey, M.; Hayes, J.; Brown, P.; Zeng, C.-W.; Lambert, T.; Friedman, J. R.; Zhang, C.-L.; Burnette, D. T.; Shepherd, D. P.; Dean, K. M.; Fiolka, R. P.
10.1101/2022.05.19.492671 — biophysics — Posted on 2022-05-20
1584 Metadata retrieval from genomics database with ffq
Galvez-Merchan, A.; Min, K. H.; Pachter, L.; Booeshaghi, A. S.
10.1101/2022.05.18.492548 — bioinformatics — Posted on 2022-05-19
1587 Guided construction of single cell reference for human and mouse lung
Guo, M.; Morley, M. P.; Wu, Y.; Du, Y.; Zhao, S.; Wagner, A.; Kouril, M.; Jin, K.; Gaddis, N.; Kitzmiller, J. A.; Stewart, K.; Basil, M. C.; Lin, S. M.; Ying, Y.; Babu, A.; Wikenheiser-Brokamp, K. A.; Mun, K. S.; Naren, A. P.; Lin, S.; Clair, G.; Adkins, J. N.; Pryhuber, G. S.; Misra, R. S.; Aronow, B. J.; Tickle, T. L.; Salomonis, N.; Sun, X.; Morrisey, E. E.; Whitsett, J. A.; Xu, Y.
10.1101/2022.05.18.491687 — bioinformatics — Posted on 2022-05-20
1588 Characterizing metabolism from bulk and single-cell RNA-seq data using METAFlux
Huang, Y.; Monhanty, V.; Dede, M.; Daher, M.; Li, L.; Rezvani, K.; Chen, K.
10.1101/2022.05.18.492580 — bioinformatics — Posted on 2022-05-20
1589 Characterizing transition cells in developmental processes from scRNA-seq data
Wang, Y.; Mohanty, V.; Dou, J.; Liang, S.; Liang, Q.; Tan, Y.; Li, J.; Li, Z.; Chen, R.; Chen, K.
10.1101/2022.05.18.492572 — bioinformatics — Posted on 2022-05-20
1594 The largest haplotype-phased and chromosome-scale genome assembly of the fungal pathogen, Puccinia polysora, by HiFi reads and Hi-C data
Liang, j.; Li, y.; Dodds, P. N.; Figueroa, M.; Sperschneider, J.; Han, S.; Tsui, C. K. M.; Zhang, K.; Li, L.; Ma, Z.; Cai, L.
10.1101/2022.05.18.492400 — genomics — Posted on 2022-05-19
1595 Nucleotide resolution genetic mapping in pigs by publicly accessible whole genome imputation
Ding, R.; Savegnago, R.; Liu, J.; Long, N.; Tan, C.; Cai, G.; Zhuang, Z.; Wu, J.; Yang, M.; Qiu, Y.; Ruan, D.; Quan, J.; Zheng, E.; Hong, L.; Li, Z.; Tan, S.; Bedhane, M.; Schnabel, R.; Steibel, J.; Gondro, C.; Yang, J.; Huang, W.; Wu, Z.
10.1101/2022.05.18.492518 — genomics — Posted on 2022-05-20
1597 Museum specimens of a landlocked pinniped reveal recent loss of genetic diversity and unexpected population connections
Heino, M. T.; Nyman, T.; Palo, J. U.; Harmoinen, J.; Valtonen, M.; Pilot, M.; Översti, S.; Salmela, E.; Kunnasranta, M.; Hoelzel, A. R.; Ruokonen, M.; Aspi, J.
10.1101/2022.05.19.492422 — evolutionary biology — Posted on 2022-05-20
1598 Non-aging despite high mutation rate - genomic insights into the evolution of Hydra
Sahm, A.; Riege, K.; Groth, M.; Bens, M.; Kraus, J. M.; Fischer, M.; Kestler, H. A.; Englert, C.; Schaible, R.; Platzer, M.; Hoffmann, S.
10.1101/2022.05.18.492491 — evolutionary biology — Posted on 2022-05-20
1599 Camera-based monitoring of Bogong moths in Alpine Australia reveals drivers of migratory behaviour
Wallace, J. R. A.; Reber, T.; Khaldy, L.; Mathews-Hunter, B.; Green, K.; Dreyer, D.; Warrant, E. J.
10.1101/2022.05.19.492631 — ecology — Posted on 2022-05-19
1601 ABHD6 selectively controls Gq-dependent increases in 2-AG production
Singh, S.; Sarroza, D.; English, A.; Whittington, D.; Dong, A.; van der Stelt, M.; Li, Y.; Zweifel, L.; Bruchas, M. R.; Land, B. B.; Stella, N.
10.1101/2022.05.18.492553 — cell biology — Posted on 2022-05-19
1602 Long-term functional regeneration of radiation damaged salivary glands through delivery of a neurogenic hydrogel
Li, J.; Sudiwala, S.; Berthoin, L.; May, A. J.; Mohabbat, S.; Gaylord, E. A.; Cruz Pacheco, N.; Lombaert, I. A. M.; Jeon, O.; Alsberg, E.; Bahney, C. S.; Knox, S. M.
10.1101/2022.05.19.491203 — cell biology — Posted on 2022-05-19
1604 Control of flight responses by a non-canonical corticolimbic pathway.
Borkar, C. D.; Fu, X.; Stelly, C. E.; Dorofeikova, M.; Le, Q.-S. E.; Vutukuri, R.; Vo, C.; Basavanhalli, S.; Duong, A.; Bean, E.; Resendez, A.; Parker, J. G.; Tasker, J. G.; Fadok, J. P.
10.1101/2022.05.19.492688 — neuroscience — Posted on 2022-05-19
1605 Larger cerebral cortex is genetically correlated with greater frontal area and dorsal thickness
Makowski, C.; Wang, H.; Srinivasan, A.; Qi, A.; Qiu, Y.; van der Meer, D.; Frei, O.; Zou, J.; Visscher, P. M.; Yang, J.; Chen, C.-H.
10.1101/2022.05.19.492686 — neuroscience — Posted on 2022-05-19
1606 The molecular fingerprint of stress resilience
Baczynska, E.; Zareba-Koziol, M.; Ruszczycki, B.; Krzystyniak, A.; Wojtowicz, T.; Bijata, K.; Pochwat, B.; Magnowska, M.; Roszkowska, M.; Figiel, I.; Masternak, J.; Dzwonek, J.; Worch, R.; Olszynski, K. H.; Wardak, A. D.; Szymczak, P.; Radwanska, K.; Jaholkowski, P.; Hogendorf, A.; Filipkowski, R. K.; Szewczyk, B.; Bijata, M.; Wlodarczyk, J.
10.1101/2022.05.19.492644 — neuroscience — Posted on 2022-05-19
1608 Deep Learning-Based Parameter Estimation for Neurophysiological Models of Neuroimaging Data
Griffiths, J. D.; Wang, Z.; Ather, S. H.; Momi, D.; Rich, S. D.; Diaconescu, A.; McIntosh, A. R.; Shen, K.
10.1101/2022.05.19.492664 — neuroscience — Posted on 2022-05-19
1612 A Preclinical Model to Investigate Normal Tissue Damage Following Fractionated Radiotherapy to the Head and Neck
Juvkam, I. S.; Zlygosteva, O.; Arous, D.; Galtung, H. K.; Malinen, E.; Soland, T. M.; Edin, N. J.
10.1101/2022.05.19.492439 — cancer biology — Posted on 2022-05-19
1615 Reproducing extracellular matrix adverse remodelling of non-ST myocardialinfarction in a large animal model
Contessotto, P.; Spelat, R.; Vysockas, V.; Krivickiene, A.; Jin, C.; Chantepie, S.; Chinello, C.; Pauza, A. G.; Rackauskas, M.; Zigmantaite, V.; Magni, F.; Papy-Garcia, D.; Karlsson, N. G.; Ereminiene, E.; Pandit, A.; Da Costa, M.
10.1101/2022.05.19.492645 — bioengineering — Posted on 2022-05-19
1622 Ariadne: Synthetic Long Read Deconvolution Using Assembly Graphs
Mak, L.; Meleshko, D.; Danko, D. C.; Barakzai, W. N.; Belchikov, N.; Hajirasouliha, I.
10.1101/2021.05.09.443255 — genomics — Posted on 2022-05-19
1623 Protective geometry and reproductive anatomy as candidate determinants of clutch size variation in pentatomid bugs
Abram, P. K.; Guerra-Grenier, E.; Brodeur, J.; Capko, C.; Aquino, M. F. S.; Beers, B.; Blassioli-Moraes, M. C.; Borges, M.; Cingolani, M. F.; Cusumano, A.; DeClercq, P.; Fernandez, C. A.; Gariepy, T. D.; Haye, T.; Hoelmer, K.; Laumann, R. A.; Lietti, M.; McPherson, J. E.; Punschke, E.; Saunders, T. E.; Zhang, J. P.; Hardy, I. C. W.
10.1101/2022.05.16.492197 — ecology — Posted on 2022-05-19
1624 Discovery and pre-clinical evaluation of antibodies to the NKG2A inhibitory receptor
Baek, D.-S.; Kim, Y.-J.; Li, W.; Macatangay, B. J.; Cyktor, J. C.; Hines, M. G.; Mellors, J. W.; Dimitrov, D. S.
10.1101/2022.05.18.492494 — immunology — Posted on 2022-05-19
1625 Nanoparticle-induced augmentation of neutrophils' phagocytosis of bacteria
Rubey, K.; Mukhitov, A. R.; Nong, J.; Wu, J.; Krymskaya, V. P.; Myerson, J. W.; Worthen, G. S.; Brenner, J. S.
10.1101/2022.05.14.491866 — immunology — Posted on 2022-05-19
1626 Widespread employment of conserved C. elegans homeobox genes in neuronal identity specification
Reilly, M. B.; Tekieli, T.; Cros, C.; Aguilar, G. R.; Lao, J.; Toker, I. A.; Vidal, B.; Leyva-Diaz, E.; Bhattacharya, A.; Cook, S. J.; Smith, J. J.; Kovacevic, I.; Gulez, B.; Fernandez, R.; Bradford, E. F.; Ramadan, Y. H.; Kratsios, P.; Bao, Z.; Hobert, O.
10.1101/2022.04.29.490095 — neuroscience — Posted on 2022-05-19
1628 Reconstitution of monoterpene indole alkaloid biosynthesis in genome engineeredNicotiana benthamiana
Dudley, Q. M.; Jo, S.; Serna Guerrero, D. A.; Chhetry, M.; Smedley, M.; Harwood, W.; Sherden, N. H.; O'Connor, S. E.; Caputi, L.; Patron, N. J.
10.1101/2021.08.12.456143 — synthetic biology — Posted on 2022-05-19
1630 COR27/28 Regulate the Evening Transcriptional Activity of the RVE8 and LNK1/2 Circadian Complex
Sorkin, M. L.; Tzeng, S.-C.; Romanowski, A.; Kahle, N.; Bindbeutel, R. K.; Hiltbrunner, A.; Yanovsky, M. J.; Evans, B.; Nusinow, D. A.
10.1101/2022.05.16.492168 — plant biology — Posted on 2022-05-19
1631 Endothelial Rbpj is essential for the education of tumour-associated macrophages
Mülfarth, R.; Alsina-Sanchis, E.; Moll, I.; Böhn, S.; Wiedmann, L.; Jordana Urriza, L.; Ziegelbauer, T.; Taylor, J.; De Angelis Rigotti, F.; Stögbauer, A.; Giaimo, B. D.; Cerwenka, A.; Borggrefe, T.; Fischer, A.; Rodriguez-Vita, J.
10.1101/2021.12.20.473423 — cancer biology — Posted on 2022-05-19
1632 Enhanced functionality of low-affinity CD19 CAR T-cells is associated with activation priming and a polyfunctional cytokine phenotype
Michelozzi, I. M.; Gomez-Castaneda, E.; Pohle, R. V. C.; Cardoso-Rodriguez, F.; Sufi, J.; Puigdevall-Costa, P.; Subraniyam, M.; Kirtsios, E.; Eddaoudi, A.; Wu, S. W.; Guvenel, A.; Fisher, J.; Ghorashian, S.; Pule, M. A.; Tape, C. J.; Castellano, S.; Amrolia, P. J.; Giustacchini, A.
10.1101/2020.09.22.291831 — cancer biology — Posted on 2022-05-19
1633 Manufacturing highly potent CD20/CD19-targeted iCasp9 regulatable CAR-T cells using the Quantum pBac-based CAR-T (qCART) system for clinical application
Chang, P. S.; Chen, Y.-C.; Hua, W.-K.; Hsu, J. C.; Tsai, J.-C.; Huang, Y.-W.; Kao, Y.-H.; Wu, P.-H.; Chang, Y.-F.; Chang, M. C.; Chang, Y. C.; Wen, K.-L. K.; Wu, S. C.-Y.
10.1101/2022.05.03.490475 — cancer biology — Posted on 2022-05-19
1637 Allosteric Inhibition of PTP1B by a Nonpolar Terpenoid
Friedman, A. J.; Liechty, E. T.; Kramer, L. D.; Sarkar, A.; Fox, J.; Shirts, M.
10.1101/2022.05.18.492571 — biochemistry — Posted on 2022-05-19
1640 A novel nematode species from the Siberian permafrost shares adaptivemechanisms for cryptobiotic survival with C. elegans dauer larva
Shatilovich, A.; Gade, V. R.; Pippel, M.; Hoffmeyer, T. T.; Tchesunov, A. V.; Stevens, L.; Winkler, S.; Hughes, G. M.; Traikov, S.; Hiller, M.; Rivkina, E.; Schiffer, P. H.; Myers, E. W.; Kurzchalia, T. V.
10.1101/2022.01.28.478251 — genomics — Posted on 2022-05-19
1641 Domestication of different varieties in the cheese-making fungus Geotrichum candidum
Bennetot, B.; Vernadet, J. P.; Perkins, V.; Hautefeuille, S.; Rodriguez de la Vega, R. C.; O'Donnell, S.; Snirc, A.; Grondin, C.; Lessard, M.-H.; Peron, A.-C.; Labrie, S.; Landaud, S.; Giraud, T.; Ropars, J.
10.1101/2022.05.17.492043 — genetics — Posted on 2022-05-19
1644 Evolutionary relationships and range evolution of greenhood orchids (subtribe Pterostylidinae): insights from plastid phylogenomics
Nargar, K.; O'Hara, K.; Mertin, A.; Bent, S.; Nauheimer, L.; Simpson, L.; Zimmer, H.; Molloy, B. P. J.; Clements, M. A.
10.1101/2022.03.30.486312 — evolutionary biology — Posted on 2022-05-19
1645 The novel Rab5 effector FERRY links early endosomes with the translation machinery
Schuhmacher, J. S.; tom Dieck, S.; Christoforidis, S.; Landerer, C.; Hersemann, L.; Seifert, S.; Giner, A.; Toth-Petroczy, A.; Kalaidzidis, Y.; Schuman, E. M.; Zerial, M.
10.1101/2021.06.20.449167 — cell biology — Posted on 2022-05-19
1647 The majority of microorganisms in gas hydrate bearing subseafloor sediments ferment macromolecules
Zhang, C.; Fang, Y.-X.; Yin, X.; Lai, H.; Kuang, Z.; Zhang, T.; Xu, X.-P.; Wegener, G.; Wang, J.-H.; Dong, X.
10.1101/2022.05.19.492412 — microbiology — Posted on 2022-05-19
1651 Distinct types of multicellular aggregates in Pseudomonas aeruginosa liquid cultures
Melaugh, G.; Martinez, V.; Baker, P.; Hill, P. J.; Howell, P. L.; Wozniak, D. J.; Allen, R. J.
10.1101/2022.05.18.492589 — microbiology — Posted on 2022-05-19
1653 Evidence of structural rearrangements and variability in pESI(like) megaplasmids of S.Infantis by resolving the pESI-like-ESBL-producing variants
Alba, P.; Carfora, V.; Feltrin, F.; Iurescia, M.; Diaconu, E. L.; Cordaro, G.; Dell'Aira, E.; Marani, I.; Giacomi, A.; Franco, A.; Battisti, A.
10.1101/2021.09.06.459061 — microbiology — Posted on 2022-05-19
1654 A reproducible and tunable synthetic soil microbial community provides new insights into microbial ecology
Coker, J.; Zhalnina, K.; Marotz, C.; Thiruppathy, D.; Tjuanta, M.; D'Elia, G.; Hailu, R.; Mahosky, T.; Rowan, M.; Northen, T.; Zengler, K.
10.1101/2022.05.19.492707 — microbiology — Posted on 2022-05-19
1655 PGC-1β maintains mitochondrial metabolism and restrains inflammatory gene expression
Guak, H.; Sheldon, R. D.; Beddows, I.; Vander Ark, A.; Shen, H.; Jones, R.; St. Pierre, J.; Ma, E.; Krawczyk, C. M.
10.1101/2022.05.18.492477 — immunology — Posted on 2022-05-19
1656 Aiolos modulates the TFH and CD4-CTL differentiation programs via reciprocal regulation of the Zfp831/TCF-1/Bcl-6 axis and CD25
Read, K. A.; Jones, D. M.; Pokhrel, S.; Hales, E. D. S.; Varkey, A.; Tuazon, J. A.; Eisele, C. D.; Abdouni, O.; Saadey, A.; Warren, R. T.; Powell, M. D.; Boss, J. M.; Hemann, E. A.; Yount, J. S.; Ghoneim, H. E.; Lio, C.-W. J.; Freud, A. G.; Collins, P. L.; Oestreich, K. J.
10.1101/2022.05.18.492485 — immunology — Posted on 2022-05-19
1657 Population-level asymmetry of the cerebral cortex: reproducibility, lifespan changes, heritability, and individual differences
Roe, J. M.; Vidal-Pineiro, D.; Amlien, I. K.; Pan, M.; Sneve, M. H.; Thiebaut de Schotten, M.; Friedrich, P.; Sha, Z.; Francks, C.; Wang, Y.; Walhovd, K. B.; Fjell, A. M.; Westerhausen, R.
10.1101/2021.11.25.469988 — neuroscience — Posted on 2022-05-19
1658 Sensitisation of colonic nociceptors by TNFα is dependent on TNFR1 expression and p38 MAPK activity
Barker, K. H.; Higham, J. P.; Pattison, L. A.; Taylor, T. S.; Chessell, I. P.; Welsh, F.; Smith, E. S. J.; Bulmer, D. C.
10.1101/2022.02.06.478183 — neuroscience — Posted on 2022-05-19
1659 Diverse task-driven modeling of macaque V4 reveals functional specialization towards semantic tasks
Cadena, S. A.; Willeke, K. F.; Restivo, K.; Denfield, G.; Sinz, F. H.; Bethge, M.; Tolias, A. S.; Ecker, A. S.
10.1101/2022.05.18.492503 — neuroscience — Posted on 2022-05-19
1660 Precision motor timing via scalar input fluctuations
Pang, R.; Duffy, A.; Bell, D.; Torok, Z. E.; Fairhall, A. L.
10.1101/2022.05.18.492498 — neuroscience — Posted on 2022-05-19
1661 Stimulus-induced changes in 1/f-like background activity in EEG
Gyurkovics, M.; Clements, G.; Low, K. A.; Fabiani, M.; Gratton, G.
10.1101/2021.12.17.473188 — neuroscience — Posted on 2022-05-19
1662 C5aR1 antagonism alters microglial polarization and mitigates disease progression in a mouse model of Alzheimers disease
Gomez-Arboledas, A.; Carvalho, K.; Balderrama-Gutierrez, G.; Chu, S.-H.; Liang, H. Y.; Schartz, N. D.; Selvan, P.; Petrisko, T. J.; Pan, M. A.; Mortazavi, A.; Tenner, A. J.
10.1101/2022.05.18.492363 — neuroscience — Posted on 2022-05-19
1664 Semaphorin 3C exacerbates liver fibrosis
De Angelis Rigotti, F.; Wiedmann, L.; Hubert, M. O.; Vacca, M.; Hasan, S. S.; Moll, I.; Carvajal, S.; Jimenez, W.; Starostecka, M.; Billeter, A. T.; Müller-Stich, B.; Wolff, G.; Ekim-Üstünel, B.; Herzig, S.; Mogler, C.; Fischer, A.; Rodriguez-Vita, J.
10.1101/2021.07.29.454292 — pathology — Posted on 2022-05-19
1665 Enhancer plasticity sustains oncogenic transformation and progression of B-Cell Acute Lymphoblastic leukemia.
Corleone, G.; Sorino, C.; Caforio, M.; Di Giovenale, S.; De Nicola, F.; Bertaina, V.; Pitisci, A.; Cortile, C.; Locatelli, F.; Folgiero, V.; Fanciulli, M.
10.1101/2022.05.18.492497 — cancer biology — Posted on 2022-05-19
1668 Floating EMG Sensors and Stimulators Wirelessly Powered and Operated by Volume Conduction for Networked Neuroprosthetics
Becerra-Fajardo, L.; Krob, M. O.; Minguillon, J.; Rodrigues, C.; Welsch, C.; Tudela-Pi, M.; Comerma, A.; Oliveira Barroso, F.; Schneider, A.; Ivorra, A.
10.1101/2022.03.09.483628 — bioengineering — Posted on 2022-05-19
1671 Membrane-Bound O-Acyltransferase 7 (MBOAT7)-Driven Lysophosphatidylinositol (LPI) Acylation in Adipocytes Contributes to Systemic Glucose Homeostasis
Massey, W.; Varadharajan, V.; Banerjee, R.; Brown, A. L.; Horak, A. J.; Hohe, R. C.; Chan, E. R.; Pan, C.; Zhang, R.; Allende, D. S.; Lusis, A. J.; Brown, J. M.
10.1101/2022.05.19.492632 — biochemistry — Posted on 2022-05-19
1673 Overexpression screen of chromosome 21 genes reveals modulators of Sonic hedgehog signaling relevant to Down syndrome
Moyer, A. J.; Fernandez, F. X.; Li, Y.; Klinedinst, D. K.; Florea, L. D.; Kazuki, Y.; Oshimura, M.; Reeves, R. H.
10.1101/2022.05.19.492735 — genetics — Posted on 2022-05-19
1678 Combined omics unravels the molecular mechanism of golden-leaf coloration in Koelreuteria paniculata 'jinye'
Guo, T.; Wu, R.; Yang, X.; Huang, S.; Miao, D.; Chen, T.; Xue, Y.; Li, J.; Gao, K.; Guo, B.; An, X.
10.1101/2022.05.19.492690 — molecular biology — Posted on 2022-05-19
1680 Held out wings RNA binding activity in the cytoplasm during early spermatogenesis
Agapiou, M.; Hopes, T.; Hobor, F.; Bretman, A.; edwards, t. a.; Aspden, J. L.
10.1101/2022.05.19.492257 — molecular biology — Posted on 2022-05-19
1685 Lipopolysaccharide synthesis and traffic in the envelope of the pathogen Brucella abortus
Servais, C.; Vassen, V.; Verhaeghe, A.; Kuster, N. S.; Carlier, E.; Phegnon, L.; Mayard, A.; De Bolle, X.
10.1101/2022.05.19.492625 — microbiology — Posted on 2022-05-19
1687 Host adaptation drives genetic diversity in a vector-borne disease system
Combs, M. A.; Tufts, D. M.; Adams, B.; Lin, Y.-P.; Kolokotronis, S.-O.; Diuk-Wasser, M. A.
10.1101/2022.05.19.492734 — microbiology — Posted on 2022-05-19
1690 Programming the lymph node immune response with Amphiphile-CpG induces potent cellular and humoral immunity following COVID-19 subunit vaccination in mice and non-human primates
Seenappa, L. M.; Jakubowski, A.; Steinbuck, M. P.; Palmer, E.; Haqq, C. M.; Carter, C.; Fontenot, J.; Villinger, F.; McNeil, L. K.; DeMuth, P. C.
10.1101/2022.05.19.492649 — immunology — Posted on 2022-05-19
1691 mRNA-based vaccines against SARS-CoV-2 do not stimulate interferon stimulatory gene expression in individuals affected by Aicardi Goutieres Syndrome.
Takanohashi, A.; Alameh, M.-G.; Woidill, S.; Hacker, J.; Davis, B.; Helman, G.; Gavazzi, F.; Adang, L.; D'Aiello, R.; Winters, P.; Cordova, D.; Khandaker, T.; Ni, H.; Tam, Y.; Lin, P.; Weissman, D.; Shults, J.; Vanderver, A.
10.1101/2022.05.18.492546 — immunology — Posted on 2022-05-19
1692 The regulatory landscapes of human ovarian ageing
Suh, Y.; Jin, C.; Wang, X.; Hudgins, A.; Gamliel, A.; Pei, M.; Kim, S.; Contreras, D.; Hoeijmakers, J.; Campisi, J.; Lobo, R.; Williams, Z.; Rosenfeld, M. G.
10.1101/2022.05.18.492547 — genomics — Posted on 2022-05-19
1694 Fibroblasts-derived from Pluripotent Cells Harboring a Single Allele Knockout in Two Pluripotency Genes Exhibit DNA Methylation Abnormalities and pluripotency induction Defects
Lasry, R.; Maoz, N.; Cheng, A. W.; Yom Tov, N.; Kulenkampff, E.; Azagury, M.; Yang, H.; Ople, C.; Markoulaki, S.; Faddah, D. A.; Makedonski, K.; Sabbag, O.; Jaenisch, R.; Buganim, Y.
10.1101/2022.05.18.492474 — cell biology — Posted on 2022-05-19
1695 Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding
Alghamdi, T. A.; Krentz, N. A. J.; Smith, N.; Spigelman, A. F.; Rajesh, V.; Jha, A.; Manning Fox, J. E.; Sun, H.; Sun, Z.; Gloyn, A. L.; MacDonald, P. E.
10.1101/2022.05.18.492530 — physiology — Posted on 2022-05-19
1703 Developmental timing of programmed DNA elimination in Paramecium tetraurelia recapitulates germline transposon evolutionary dynamics
Zangarelli, C.; Arnaiz, O.; Bourge, M.; Gorrichon, K.; Jaszczyszyn, Y.; Mathy, N.; Escoriza, L.; Betermier, M.; Regnier, V.
10.1101/2022.05.18.492358 — genomics — Posted on 2022-05-19
1704 Trait-dependent diversification in angiosperms: patterns, models and data
Helmstetter, A. J.; Zenil-Ferguson, R.; Sauquet, H.; Otto, S. P.; Mendez, M.; Vallejo-Marin, M.; Schönenberger, J.; Burgarella, C.; Anderson, B. J.; de Boer, H.; Glemin, S.; Käfer, J.
10.1101/2022.05.18.490882 — evolutionary biology — Posted on 2022-05-19
1705 Serial depletion of Baltic herring since the Viking Age revealed by ancient DNA and population genomics
Atmore, L. M.; Martinez-Garcia, L.; Makowiecki, D.; Andre, C.; Lougas, L.; Barrett, J. H.; Star, B.
10.1101/2022.05.18.492457 — ecology — Posted on 2022-05-19
1707 Using NAMs to characterize chemical bioactivity at the transcriptomic, proteomic and phosphoproteomic levels
Li, Y.; zhang, Z.; Jiang, S.; Xu, F.; Tulum, L.; Li, K.; Liu, S.; Li, S.; Chang, L.; Liddell, M.; Tu, F.; Gu, X.; Carmichael, P. L.; White, A.; Peng, S.; Zhang, Q.; Li, J.; Zuo, T.; Kukic, P.; Xu, P.
10.1101/2022.05.18.492410 — pharmacology and toxicology — Posted on 2022-05-19
1709 Cellular senescence in malignant cells promotes tumor progression in mouse and patient Glioblastoma
Salam, R.; Saliou, A.; Bielle, F.; Bertrand, M.; Antoniewski, C.; Carpentier, C.; Alentorn, A.; Capelle, L.; Sanson, M.; Huillard, E.; Bellenger, L.; Guegan, J.; Le Roux, I.
10.1101/2022.05.18.492465 — cancer biology — Posted on 2022-05-19
1710 Increased CaMKK2 expression is an adaptive response that maintains the fitness of tumor-infiltrating natural killer cells
Juras, P. K.; Racioppi, L.; Mukherjee, D.; Artham, S.; Gao, X.; D'Agostino, L. A.; Chang, C.-Y.; McDonnell, D. P.
10.1101/2022.05.18.492328 — cancer biology — Posted on 2022-05-19
1714 Improved deterrence of birds using an artificial predator, the RobotFalcon
Storms, R. F.; Carere, C.; Musters, R. J.; van Gasteren, H.; Verhulst, S.; Hemelrijk, C. K.
10.1101/2022.05.18.492297 — animal behavior and cognition — Posted on 2022-05-19
1716 Massive Horizontal Gene Transfer in Amphioxus Illuminates the Early Evolution of Deuterostomes
Xiong, Q.; Yang, K. Y.; Zeng, X.; Wang, M.; Ng, P. K.-S.; Zhou, J.-W.; Ng, J. K.-W.; Law, C. T.-Y.; Du, Q.; Xu, K.; Falkenberg, L. J.; Mao, B.; Chen, J.-Y.; Tsui, S. K.-W.
10.1101/2022.05.18.492404 — evolutionary biology — Posted on 2022-05-19
1717 Two different mental disc forms in the Tashan cave Garra: different species or ecotypes?
Hashemzadeh Segherloo, I.; Najafi Chaloshtory, S.; Naser, M. D.; Yasser, A. G.; Tabatabaei, S. N.; Piette-Lauziere, G.; Mashtizadeh, A.; Elmi, A.; Sedighi, O.; Changizi, A.; Hallerman, E.; Bernatchez, L.
10.1101/2022.05.18.492420 — ecology — Posted on 2022-05-19
1719 Mating disrupts morning anticipation in Drosophila melanogaster females 2
Riva, S.; Ispizua, J. I.; Breide, M. T.; Polcownuk, S.; Lobera, J. R.; Ceriani, M. F.; Risau Gusman, S.; Franco, D. L.
10.1101/2022.05.18.492405 — neuroscience — Posted on 2022-05-19
1720 Determination of cross-tissue and tissue-specific aging changes in murine proteomes
Keele, G. R.; Zhang, J.-G.; Szpyt, J.; Korstanje, R.; Gygi, S.; Churchill, G. A.; Schweppe, D. K.
10.1101/2022.05.17.492125 — systems biology — Posted on 2022-05-19
1721 PPARγ/ETV2 Axis Regulates Endothelial-to-Mesenchymal Transition in Pulmonary Hypertension
Lee, D. H.; Kim, M.; Chang, S. S.; Jang, A. J.; Kim, J.; Ma, J.; Passineau, M. J.; Benza, R. L.; Karmouty-Quintana, H.; Lam, W. A.; Sutliff, R. L.; Hart, C. M.; Park, C.; Kang, B.-Y.
10.1101/2022.05.17.492293 — physiology — Posted on 2022-05-19
1722 Cross regulation between the molecular clock and kidney inflammatory, metabolic and fibrotic responses
Rey-Serra, C.; Tituana, J.; Lin, T.; Herrero, J. I.; Miguel, V.; Barbas, C.; Meseguer, A.; Ramos, R.; Firsov, D.; Chaix, A.; Panda, S.; Lamas, S.
10.1101/2022.05.18.492458 — physiology — Posted on 2022-05-19
1724 Longitudinal white matter alterations in SIVmac239 infected rhesus monkeys with and without regular cART treatment
Li, H.; Liu, J.; Nguchu, B. A.; Liu, D.; Qi, Y.; Xire, A.; Han, S.; Gao, Y.; Wang, X.; Qiao, H.; Cai, C.; Huang, X.
10.1101/2022.05.17.492395 — animal behavior and cognition — Posted on 2022-05-19
1725 Pervasive gene duplications as a major evolutionary driver of coral biology
Noel, B.; Denoeud, F.; Rouan, A.; Buitrago-Lopez, C.; Capasso, L.; Poulain, J.; Boissin, E.; Pousse, M.; Da Silva, C.; Couloux, A.; Armstrong, E.; Carradec, Q.; Cruaud, C.; Labadie, K.; Le-Hoang, J.; Tambutte, S.; Barbe, V.; Moulin, C.; Bourdin, G.; Iwankow, G.; Romac, S.; Allemand, D.; Planes, S.; Gilson, E.; Zoccola, D.; Wincker, P.; Voolstra, C.; Aury, J.-M.
10.1101/2022.05.17.492263 — genomics — Posted on 2022-05-19
1734 COVID-19 lockdown reveals fish density may be much higher in marine reserves
Gonzalez, M. O.; Bonilla, H. R.; Alarcon, I. A.; Uribe, R. V.; Olivier, D.
10.1101/2022.05.17.492376 — ecology — Posted on 2022-05-19
1735 The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency
Athanasouli, P.; Balli, M.; De Jaime-Soguero, A.; Boel, A.; Papanikolaou, S.; van der Veer, B. K.; Janiszewski, A.; Francis, A.; El Laithy, Y.; Lo Nigro, A.; Aulicino, F.; Koh, K. P.; Pasque, V.; Cosma, M. P.; Verfaillie, C.; Zwijsen, A.; Heindryckx, B.; Nikolaou, C.; Lluis, F.
10.1101/2022.05.18.492419 — developmental biology — Posted on 2022-05-19
1737 EDGE2: advancing the prioritisation of threatened evolutionary history for conservation action
Gumbs, R.; Gray, C. L.; Bohm, M.; Burfield, I. J.; Couchman, O. R.; Faith, D. P.; Forest, F.; Hoffmann, M.; Isaac, N. J. B.; Jetz, W.; Mace, G. M.; Mooers, A. O.; Safi, K.; Scott, O.; Steel, M.; Tucker, C. M.; Pearse, W. D.; Owen, N. R.; Rosindell, J.
10.1101/2022.05.17.492313 — zoology — Posted on 2022-05-19
1738 Endothelial neuropilin-1 and neuropilin-2 are essential for tumour angiogenesis
Benwell, C. J.; Johnson, R. T.; Taylor, J. A. G. E.; Price, C. A.; Robinson, S. D.
10.1101/2022.05.17.492307 — cancer biology — Posted on 2022-05-19
1739 scMoMaT: Mosaic integration of single cell multi-omics matrices using matrix trifactorization
Zhang, Z.; Sun, H.; Chen, X.; Mariappan, R.; Chen, X.; Jain, M.; Efremova, M.; Rajan, V.; Teichmann, S.; Zhang, X.
10.1101/2022.05.17.492336 — bioinformatics — Posted on 2022-05-19
1740 Rtapas: An R package to assess cophylogenetic signal between two evolutionary histories
Llaberia-Robledillo, M.; Lucas-Lledo, J. I.; Perez-Escobar, O. A.; Krasnov, B. R.; Balbuena, J. A.
10.1101/2022.05.17.492291 — evolutionary biology — Posted on 2022-05-19
1741 Conservation of nitrogenase functionality over long timescales
Garcia, A. K.; Harris, D.; Rivier, A.; Carruthers, B.; Barros, A. P.; Seefeldt, L.; Kacar, B.
10.1101/2022.05.17.492308 — evolutionary biology — Posted on 2022-05-19
1742 Epitope Mapping of SARS-CoV-2 Spike Protein Reveals Distinguishable Antibody Binding Activity of Vaccinated and Infected Individuals.
Felbinger, N.; Trudil, D. P.; Loomis, L. L.; Ascione, R.; Siragusa, G. R.; Haba, S.; Mucci, A.; Claycomb, M.; Snowberger, S.; Luke, B.; Tsang, S.; Francesconi, S. C.
10.1101/2022.04.13.487697 — immunology — Posted on 2022-05-19
1743 USP11 promotes endothelial apoptosis-resistance in pulmonary hypertension by deubiquitinating HINT3
Jang, A. J.; Tseng, V.; Kim, J. S.; Stearman, R. S.; Zhao, Y.; Zhao, J.; Choi, J.; Lister, J.; Passineau, M. J.; Lam, W. A.; Park, C.; Benza, R. L.; Kang, B.-Y.
10.1101/2022.05.17.492159 — physiology — Posted on 2022-05-19
1744 Genomic screening reveals UBA1 as a potent and druggable target in c-MYC-high TNBC models
Jacob, S.; Turner, T. H.; Cai, J.; Floros, K. V.; Yu, A. K.; Coon, C. M.; Khatri, R.; Alzubi, M. A.; Jakubik, C. T.; Bouck, Y. M.; Puchalapalli, M.; Shende, M.; Dozmorov, M. G.; Boikos, S.; Hu, B.; Harrell, J. C.; Benes, C. H.; Koblinski, J.; Costa, C.; Faber, A. C.
10.1101/2022.05.17.491908 — cancer biology — Posted on 2022-05-19
1747 MCell4 with BioNetGen: A Monte Carlo Simulator of Rule-Based Reaction-Diffusion Systems with Python Interface
Husar, A.; Ordyan, M.; Garcia, G. C.; Yancey, J. G.; Saglam, A. S.; Faeder, J.; Bartol, T. M.; Sejnowski, T. J.
10.1101/2022.05.17.492333 — biophysics — Posted on 2022-05-19
1752 Considerations for Deconvolution: A Case Study with GTEx Coronary Artery Tissues
Brehm, Z. P.; Sherina, V.; Rosenberg, A. Z.; Halushka, M. K.; McCall, M. N.
10.1101/2022.05.17.492324 — bioinformatics — Posted on 2022-05-19
1753 Long-duration and non-invasive photoacoustic imaging of multiple anatomical structures in a live mouse using a single contrast agent
KHADRIA, A.; Paavola, C. D.; Zhang, Y.; Davis, S. P. X.; Grealish, P.; Maslov, K.; Shi, J.; Beals, J. M.; Oladipupo, S. S.; Wang, L. V.
10.1101/2022.05.17.491718 — bioengineering — Posted on 2022-05-19
1758 Domestication of different varieties in the cheese-making fungus Geotrichum candidum
Bennetot, B.; Vernadet, J. P.; Perkins, V.; Hautefeuille, S.; Rodriguez de la Vega, R. C.; O'Donnell, S.; Snirc, A.; Grondin, C.; Lessard, M.-H.; Peron, A.-C.; Labrie, S.; Landaud, S.; Giraud, T.; Ropars, J.
10.1101/2022.05.17.492043 — genetics — Posted on 2022-05-19
1760 Evolution and diversification dynamics of butterflies
Kawahara, A. Y.; Storer, C.; Carvalho, A. P. S.; Plotkin, D. M.; Condamine, F.; Braga, M. P.; Ellis, E. A.; St Laurent, R. A.; Li, X.; Barve, V.; Cai, L.; Earl, C.; Frandsen, P. B.; Owens, H. L.; Valencia-Montoya, W. A.; Aduse-Poku, K.; Toussaint, E. F. A.; Dexter, K. M.; Doleck, T.; Markee, A.; Messcher, R.; Nguyen, Y.-L.; Badon, J. A. T.; Benitez, H. A.; Braby, M. F.; Buenavente, P. A. C.; Chan, W.-P.; Collins, S. C.; Childers, R. A. R.; Dankowicz, E.; Eastwood, R.; Fric, Z. F.; Gott, R.; Hall, J. P. W.; Hallwachs, W.; Hardy, N. B.; Sipe, R. L. H.; Heath, A.; Hinolan, J. D.; Homziak, N. T.;
10.1101/2022.05.17.491528 — evolutionary biology — Posted on 2022-05-19
1761 Cosmopolitan Scolytinae: strong common drivers but too many singularities for accurate prediction
Gregoire, J.-C.; Jactel, H.; Hulcr, J.; Battisti, A.; Inward, D.; Petter, F.; Grousset, F.
10.1101/2022.05.17.492299 — ecology — Posted on 2022-05-19
1762 Fruitful female fecundity after feeding Gryllodes sigillatus royal jelly
Muzzatti, M. J.; McConnell, E.; Neave, S.; MacMillan, H. A.; Bertram, S. M.
10.1101/2022.05.17.492327 — ecology — Posted on 2022-05-19
1763 Microglia maintain homeostatic conditions in the developing rostral migratory stream.
Meller, S. J.; Sanchez, E. M. H.; Martin-Lopez, E.; Liberia, T.; GREER, C. A.
10.1101/2022.05.17.492317 — neuroscience — Posted on 2022-05-19
1764 Dynamics of the most common pathogenic mtDNA variant m.3243A>G demonstrate frequency-dependency in blood and positive selection in the germline.
Franco, M.; Pickett, S. J.; Fleishmann, Z.; Khrapko, M.; Cote-LHeureux, A.; Aidlen, D.; Stein, D.; Markuzon, N.; Popadin, K.; Braverman, M.; Woods, D. C.; Tilly, J. L.; Turnbull, D.; Khrapko, K.
10.1101/2021.02.26.433045 — genomics — Posted on 2022-05-19
1767 Self-generation of goal-directed choices in a distributed dopaminergic andprefrontal circuit
Bousseyrol, E.; Didienne, S.; Takillah, S.; Solie, C.; Come, M.; Ahmed Yahia, T.; Mondoloni, S.; Vicq, E.; Tricoire, L.; Mourot, A.; Naude, J.; Faure, P.
10.1101/2022.05.19.492598 — neuroscience — Posted on 2022-05-19
1768 Glia-mediated cerebellar pain modulation
Kim, S. H.; Lee, J.; Roh, S.-E.; Jang, M.; Kim, S.; Lee, J. H.; Seo, J.; Hwang, J. Y.; Lee, Y.-S.; Shigetomi, E.; Lee, C. J. J.; Koizumi, S.; KIM, S. K.; Kim, S. J.
10.1101/2022.05.18.489807 — neuroscience — Posted on 2022-05-19
1771 Mitotic chromosome condensation resets chromatin to maintain transcriptional homeostasis
Ramos-Alonso, L.; Holland, P.; Le Gras, S.; Zhao, X.; Jost, B.; Bjoras, M.; Barral, Y.; Enserink, J. M.; Chymkowitch, P.
10.1101/2022.05.11.491439 — molecular biology — Posted on 2022-05-19
1772 Disease-modifying effects of sodium selenate in a model of drug-resistant, temporal lobe epilepsy.
Casillas-Espinosa, P. M.; Anderson, A.; Harutyunyan, A.; Li, C.; Lee, J.; Braine, E.; Sun, M.; Huang, C.; Barlow, C.; Shah, A.; Schittenhelm, R. B.; Mychasiuk, R.; Jones, N.; Shultz, S.; O'Brien, T.
10.1101/2022.05.17.492323 — neuroscience — Posted on 2022-05-19
1773 COR27/28 Regulate the Evening Transcriptional Activity of the RVE8 and LNK1/2 Circadian Complex
Sorkin, M. L.; Tzeng, S.-C.; Romanowski, A.; Kahle, N.; Bindbeutel, R. K.; Hiltbrunner, A.; Yanovsky, M. J.; Evans, B.; Nusinow, D. A.
10.1101/2022.05.16.492168 — plant biology — Posted on 2022-05-19
1778 Nuclear GAPDH cascade mediates pathological cardiac hypertrophy
Zhang, M.; Kariya, T.; Numata, G.; Sasaki, H.; Sasaki, M.; Ramos, A.; Nakamura, S.; Iwakiri, M.; Koitabashi, N.; Zhu, G.; Tsujimura, T.; Lee, D.-i.; Tristan, C.; Shahani, N.; Tsuchiya, Y.; Jaaro-Peled, H.; Sasano, T.; Slusher, B. S.; Kass, D.; Saitoh, T.; Ishizuka, K.; Sawa, A.; Takimoto, E.
10.1101/844902 — molecular biology — Posted on 2022-05-19
1780 Brain histone beta-hydroxy-butyrylation couples metabolism with gene expression
Cornuti, S.; Chen, S.; Lupori, L.; Finamore, F.; Samad, M.; Raimondi, F.; Mazziotti, R.; Magnan, C.; Rocchiccioli, S.; Baldi, P.; Pizzorusso, T.; Tognini, P.
10.1101/2021.06.28.449924 — neuroscience — Posted on 2022-05-19
1781 The vestibular calyceal junction is dismantled in response to diverse injuring stimuli in rats and humans
Maroto, A. F.; Borrajo, M.; Callejo, A.; Amilibia, E.; Perez-Grau, M.; Roca-Ribas, F.; Castellanos, E.; Barrallo-Gimeno, A.; Llorens, J.
10.1101/2022.05.17.492294 — neuroscience — Posted on 2022-05-19
1782 Disinhibition of Rab10 gates AMPAR insertion and spine enlargement during long-term potentiation
Wang, J.; Nishiyama, J.; Parra-Bueno, P.; Okaz, E.; Oz, G.; Liu, X.; Suponitsky-Kroyter, I.; McGraw, T. E.; Szatmari, E. M.; Yasuda, R.
10.1101/2022.05.17.492345 — neuroscience — Posted on 2022-05-19
1783 Boosting chloroplast ribosome biogenesis by a plastidial DEAD-box RNA helicase is critical for high light acclimation
Djouani-Tahri, E. B.; Nellaepalli, S.; Auroy, P.; Billon, E.; Burlacot, A.; Chaux-Jukic, F.; Cuine, S.; Epting, V.; Huleux, M.; Ghysels, B.; Schulz-Raffelt, M.; Te, I.; Brugiere, S.; Coute, Y.; Takahashi, Y.; Li-Beisson, Y.; Peltier, G.
10.1101/2022.05.16.492170 — plant biology — Posted on 2022-05-19
1784 OGG1 inhibitor TH5487 alleviates allergic airway inflammation in mice
Tanner, L.; Bergwik, J.; Bhongir, R. K.; Pan, L.; Dong, C.; Kalderen, C.; Helleday, T.; Boldogh, I.; Adner, M.; Egesten, A.
10.1101/2022.05.17.492235 — pharmacology and toxicology — Posted on 2022-05-19
1785 On the reproductive mechanism of Gram-negative protocells
Kanaparthi, D.; Lampe, M.; Krohn, J. H.; Zhu, B.; Klingl, A.; Lueders, T.
10.1101/2021.11.25.470037 — biophysics — Posted on 2022-05-19
1787 ER translocation of suboptimal targeting sequences depends on Sec61β/Sbh1 and its phosphorylation
Barbieri, G.; Simon, J.; Lupusella, C. R.; Pereira, F.; Elia, F.; Meyer, H.; Schuldiner, M.; Hanes, S. D.; Nguyen, D.; Helms, V.; Romisch, K.
10.1101/2022.05.18.492448 — biochemistry — Posted on 2022-05-19
1788 Mindin differentially regulates fibroblast subpopulations via distinct members of the Src family kinases during fibrogenesis.
Kataria, S.; Rana, I.; Badarinath, K.; Zaarour, R. F.; Kansagara, G.; Zirmire, R.; Dam, B.; Kumar, P.; Gulyani, A.; Jamora, C.
10.1101/2022.05.17.492347 — cell biology — Posted on 2022-05-19
1789 Homeostatic feedback between lysosomal mTORC1 and mTORC2-AKT signaling controls nutrient uptake in brown adipose tissue
Liebscher, G.; Vujic, N.; Schreiber, R.; Heine, M.; Krebiehl, C.; Dutamare, M.; Lamberti, G.; de Smet, C. H.; Hess, M. W.; O. Eichmann, T.; Hölzl, S.; Scheja, L.; Heeren, J.; Kratky, D.; Huber, L. A.
10.1101/2022.05.17.492242 — cell biology — Posted on 2022-05-19
1790 Lung macrophages utilize cathepsin K-dependent phagosomal machinery to degrade intracellular collagen
Härtlova, A.; Fabrik, I.; Bilkei-Gorzo, O.; Fabrikova, D.; Öberg, M.; Fuchs, J.; Sihlbom, C.; Göransson, M.
10.1101/2022.05.16.492085 — cell biology — Posted on 2022-05-19
1791 The Nse5/6-like SIMC1-SLF2 Complex Localizes SMC5/6 to Viral Replication Centers
Oravcova, M.; Nie, M.; Zilio, N.; Maeda, S.; Jami-Alahmadi, Y.; Lazzerini-Denchi, E.; Wohlschlegel, J. A.; Ulrich, H.; Otomo, T.; Boddy, M.
10.1101/2022.05.17.492321 — cell biology — Posted on 2022-05-19
1793 Proliferative and quiescent human gastric cancer stem-like cells are associated with differential chemoresistance and patient mortality
Ang, K. S.; Lee, H. K.; Chevrier, M.; Goh, M.; Ling, J.; Koh, V.; Zhang, X.; Tan, J. C.; Lee, N.; Erdal Irac, S.; Lim, Z. M.; Lum, J.; Tay, A.; Antoine Dutertre, C.; Tang, C.; Wong, C.; Lau, M. C.; Lim, C. J.; Chuah, S. W. J.; Lim, S.; Yeong, J. P. S.; Chew, V.; Larbi, A.; Singhal, A.; Poidinger, M.; Ng, M. C. H.; Wu Howland, S.; Tan, P.; Ginhoux, F.; So, J.; Yong, W. P.; Chen, J.
10.1101/2020.10.23.351726 — immunology — Posted on 2022-05-19
1794 Quantitative MRI reveals differences in striatal myelin in children with DLD
Krishnan, S.; Cler, G.; Smith, H. J.; Willis, H. E.; Asaridou, S. S.; Healy, M. P.; Papp, D.; Watkins, K. E.
10.1101/2021.10.18.464793 — neuroscience — Posted on 2022-05-19
1798 Mitigating the Bfl-1-mediated antiapoptotic pathway in diffuse large B cell lymphoma by inhibiting HDACs
Yoon, S.-s.; Park, E.; Lee, C.; Park, J.; Liu, J.; Hong, J.; Shin, D.-Y.; Byun, J. M.; Yun, H.; Koh, Y.
10.1101/2022.03.28.486020 — cancer biology — Posted on 2022-05-19
1802 The Indirect Pathway of the Basal Ganglia Promotes Negative Reinforcement, But Not Motor Suppression
Isett, B. R.; Nguyen, K. P.; Schwenk, J. C.; Snyder, C. N.; Adegbesan, K. A.; Ziausyte, U.; Gittis, A. H.
10.1101/2022.05.18.492478 — neuroscience — Posted on 2022-05-19
1803 Emergent low-frequency activity in cortico-cerebellar networks with motor skill learning
Fleischer, P. J.; Abbasi, A.; Fealy, A. W.; Danielsen, N. P.; Sandhu, R.; Raj, P. R.; Gulati, T.
10.1101/2022.05.18.491978 — neuroscience — Posted on 2022-05-19
1804 Molecular cloning and recombinant protein expression of 9-Lipoxygenase gene from Solanum tuberosum in Pichia pastoris yeast cells
Olengo, A.; Nantezza, A.; Elvio, H. B. P.; Garbe, L.-A.; Marillonnet, S.; Gru?tzner, R.; Saimo-Kahwa, M.; Schultz, F.; Koch, M.
10.1101/2022.05.18.492528 — molecular biology — Posted on 2022-05-18
1805 Distinct nano-structures support a multifunctional role of actin at presynapses
Bingham, D.; Wernert, F.; Da Costa Moura, J.; Boroni-Rueda, F.; van Bommel, N.; Caillol, G.; Papandreou, M.-J.; Leterrier, C.
10.1101/2022.05.18.492480 — neuroscience — Posted on 2022-05-18
1808 Modeling clonal evolution and oncogenic dependency in vivo in the context of hematopoietic transformation
Bowman, R. L.; Dunbar, A.; Mishra, T.; Xiao, W.; Waarts, M. R.; Fernandez Maestre, I.; Eisman, S. E.; Cai, L.; Cai, S. F.; Sanchez Vela, P.; Mowla, S.; Martinez Benitez, A. R.; Park, Y.; Csete, I. S.; Krishnan, A.; Lee, D.; Boorady, N.; Potts, C. R.; Jenkins, M. T.; Carroll, M. P.; Meyer, S. E.; Miles, L. A.; Ferrell, P. B.; Trowbridge, J. J.; Levine, R. L.
10.1101/2022.05.18.492524 — cancer biology — Posted on 2022-05-18
1809 The archaeological potential of the northern Luangwa Valley, Zambia: the Luwumbu basin.
Ariane, B.; Bisson, M.; Schilt, F. C.; Tolan, S.; Drapeau, M.; Aleman, J.; Peros, M.
10.1101/2022.05.18.492447 — evolutionary biology — Posted on 2022-05-18
1810 Persistence of phenotypic responses to short-term heat stress in the tabletop coral Acropora hyacinthus
Walker, N. S.; Cornwell, B. H.; Nestor, V.; Armstrong, K. C.; Golbuu, Y.; Palumbi, S. R.
10.1101/2022.05.18.492444 — ecology — Posted on 2022-05-18
1812 Jak2V617F Reversible Activation Shows an Essential Requirement for Jak2V617F in Myeloproliferative Neoplasms
Dunbar, A.; Bowman, R. L.; Park, Y.; Izzo, F.; Myers, R. M.; Karzai, A.; Jun Kim, W.; Fernandez Maestre, I.; Waarts, M. R.; Nazir, A.; Xiao, W.; Brodsky, M.; Farina, M.; Cai, L.; Cai, S. F.; Wang, B.; An, W.; Yang, J. L.; Mowla, S.; Eisman, S. E.; Mishra, T.; Houston, R.; Guzzardi, E.; Martinez Benitez, A. R.; Viny, A.; Koche, R.; Landau, D. A.; Levine, R. L.
10.1101/2022.05.18.492332 — cancer biology — Posted on 2022-05-18
1814 Localization free super-resolution microbubble velocimetry using a long short-term memory neural network
Chen, X.; Lowerison, M.; Dong, Z.; Sekaran, N. C.; Huang, C.; Chen, S.; Fan, T. M.; Llano, D. A.; Song, P.
10.1101/2021.10.01.462404 — bioengineering — Posted on 2022-05-18
1815 Chemoproteomics-Enabled Discovery of a Covalent Molecular Glue Degrader Targeting NF-κB
King, E. A.; Cho, Y.; Dovala, D.; McKenna, J. M.; Tallarico, J. A.; Schirle, M.; Nomura, D. K.
10.1101/2022.05.18.492542 — biochemistry — Posted on 2022-05-18
1816 Extensive mosaicism by somatic L1 retrotransposition in normal human cells
Nam, C. H.; Youk, J.; Kim, J. Y.; Lim, J.; Park, J. W.; Oh, S. A.; Lee, H. J.; Park, J. W.; Jeong, S.-Y.; Lee, D.-S.; Oh, J. W.; Han, J.; Lee, J.; Kwon, H. W.; Kim, M. J.; Ju, Y. S.
10.1101/2022.05.18.492429 — genomics — Posted on 2022-05-18
1817 The epigenomic landscape of single vascular cells reflects developmental origin and identifies disease risk loci
Weldy, C. S.; Cheng, P. P.; Pedroza, A. J.; Dalal, A. R.; Sharma, D.; Kim, H.-J.; Shi, H.; Nguyen, T.; Kundu, R. K.; Fischbein, M. P.; Quertermous, T.
10.1101/2022.05.18.492517 — genomics — Posted on 2022-05-18
1822 Limited Cross-Species Virus Transmission in a Spatially Restricted Coral Reef Fish Community
Costa, V. A.; Bellwood, D. R.; Mifsud, J. C. O.; Geoghegan, J. L.; Holmes, E. C.; Harvey, E.
10.1101/2022.05.17.492384 — microbiology — Posted on 2022-05-18
1824 Growth, organic matter release, aggregation and recycling during a diatom bloom: A model-based analysis of a mesocosm experiment
Kerimoglu, O.; Hintz, N. H.; Lücken, L.; Blasius, B.; Böttcher, L.; Bunse, C.; Dittmar, T.; Heyerhoff, B.; Mori, C.; Striebel, M.; Simon, M.
10.1101/2022.05.18.492269 — microbiology — Posted on 2022-05-18
1825 Gut microbiota of homing pigeons shows summer-winter variation under constant diet indicating a substantial effect of temperature
Dietz, M. W.; Matson, K. D.; Versteegh, M. A.; van der Velde, M.; Parmentier, H. K.; Arts, J. A.; Falcao Salles, J.; Tieleman, B. I.
10.1101/2022.05.18.492417 — microbiology — Posted on 2022-05-18
1828 Increasing protein stability by inferring substitution effects from high-throughput experiments
Norrild, R. K.; Johansson, K. E.; O'Shea, C.; Morth, J. P.; Lindorff-Larsen, K.; Winther, J. R.
10.1101/2022.05.18.492418 — biochemistry — Posted on 2022-05-18
1830 Phenol Sensing in Nature Modulated via a Conformational Switch Governed by Dynamic Allostery
Singh, J.; Sahil, M.; Ray, S.; Dcosta, C.; Panjikar, S.; Krishnamoorthy, G.; Mondal, J.; Anand, R.
10.1101/2022.05.18.492265 — biochemistry — Posted on 2022-05-18
1831 Structural analysis of cholesterol binding and sterol selectivity by ABCG5/G8
Farhat, D.; Rezaei, F.; Ristovski, M.; Yang, Y.; Stancescu, A.; Dzimkova, L.; Samnani, S.; Couture, J.-F.; Lee, J.-Y.
10.1101/2022.05.18.492512 — biochemistry — Posted on 2022-05-18
1833 Genomic epidemiology and multilevel genome typing of Australian Salmonella enterica serovar Enteritidis
Luo, L.; Payne, M.; Wang, Q.; Kaur, S.; Rathnayake, I. U.; Graham, R.; Gall, M.; Draper, J.; Martinez, E.; Octavia, S.; Tanaka, M. M.; Jennison, A. V.; Sintchenko, V.; Lan, R.
10.1101/2022.05.18.492204 — genomics — Posted on 2022-05-18
1835 Parasites make hosts more profitable but less available to predators
Prosnier, L.; Loeuille, N.; Hulot, F. D.; Renault, D.; Piscart, C.; Bicocchi, B.; Deparis, M.; Lam, M.; Medoc, V.
10.1101/2022.02.08.479552 — ecology — Posted on 2022-05-18
1838 Mutant huntingtin exon-1 impaired GTPCH and DHFR expression in plants and mice
Hung, C.-Y.; Zhu, C.-S.; Kittur, F. S.; He, M.; Arning, E.; Zhang, J.; Johnson, A. J.; Jawa, G. S.; Thomas, M. D.; Ding, T. T.; Xie, J.
10.1101/2022.05.18.492514 — molecular biology — Posted on 2022-05-18
1839 Chromosome folding and prophage activation reveal gut-specific genome dynamics of bacteria in the OMM12 consortium
Lamy-Besnier, Q.; Bignaud, A.; Garneau, J.; Titecat, M.; Conti, D.; Von Strempel, A.; Monot, M.; Stecher, B.; Koszul, R.; Debarbieux, L.; Marbouty, M.
10.1101/2022.05.18.492453 — microbiology — Posted on 2022-05-18
1840 Bacteroides muris sp. nov. isolated from the cecum of wild-derived house mice
Fokt, H.; Unni, R.; Repnik, U.; Schmitz, R. A.; Bramkamp, M.; Baines, J. F.; Unterweger, D.
10.1101/2022.05.18.490454 — microbiology — Posted on 2022-05-18
1843 Community review: a robust and scalable selection system for resource allocation within open science and innovation communities
Graham, C. L. B.; Landrain, T. E.; Vjestica, A.; Greshake Tzovoras, B.; Masselot, C.; Lawton, E.; Haenel, L.; Blondel, L.; Santolini, M.
10.1101/2022.04.25.489391 — scientific communication and education — Posted on 2022-05-18
1844 Targeted in silico characterization of fusion transcripts in tumor and normal tissues via FusionInspector
Haas, B.; Dobin, A.; Ghandi, M.; Van Arsdale, A.; Tickle, T. L.; Robinson, J. T.; Gillani, R.; Kasif, S.; Regev, A.
10.1101/2021.08.02.454639 — bioinformatics — Posted on 2022-05-18
1845 Direct specification of lymphatic endothelium from non-venous angioblasts
Lupu, I.-E.; Kirschnick, N.; Weischer, S.; Martinez-Corral, I.; Forrow, A.; Lahmann, I.; Riley, P. R.; Zobel, T.; Makinen, T.; Kiefer, F.; Stone, O. A.
10.1101/2022.05.11.491403 — developmental biology — Posted on 2022-05-18
1846 Analyses of circRNA expression throughout circadian rhythm reveal a strong link between Cdr1as and light-induced phase shifts in the SCN
Ivanov, A.; Mattei, D.; Radscheit, K.; Compagnion, A.-C.; Pett, P.; Herzel, H.; Paolicelli, R. C.; Piwecka, M.; Meyer, U.; Beule, D.
10.1101/2022.05.18.492346 — systems biology — Posted on 2022-05-18
1848 Characterization of protein isoform diversity in human umbilical vein endothelial cells (HUVECs) via long-read proteogenomics
Mehlferber, M. M.; Jordan, B. T.; Jeffery, E. D.; Sheynkman, L.; Saquing, J.; Acharya, B. R.; Hirschi, K. K.; Sheynkman, G. M.
10.1101/2022.05.17.490813 — systems biology — Posted on 2022-05-18
1852 Myeloid cell evolution uncovered by shrimp immune cell analysis at single-cell resolution
Yang, P.; Chen, Y.; Huang, Z.; Xia, H.; Cheng, L.; Wu, H.; Zhang, Y.; Wang, F.
10.1101/2022.05.17.492277 — immunology — Posted on 2022-05-18
1856 A conserved enzyme of smut fungi facilitates cell-to-cell movement in the plant bundle sheath
Oekmen, B.; Jaeger, E.; Schilling, L.; Finke, N.; Lee, Y. J.; Wemhoener, R.; Pauly, M.; Neumann, U.; Doehlemann, G.
10.1101/2022.05.17.492292 — plant biology — Posted on 2022-05-18
1857 stainlib: a python library for augmentation and normalization of histopathology H&E images
Otalora, S.; Marini, N.; Podareanu, D.; Hekster, R.; Tellez, D.; van der Laak, J.; Müller, H.; Atzori, M.
10.1101/2022.05.17.492245 — bioinformatics — Posted on 2022-05-18
1860 ERnet: a tool for the semantic segmentation and quantitative analysis of endoplasmic reticulum topology for video-rate super-resolution imaging
Lu, M.; Christensen, C. N.; Weber, J. M.; Konno, T.; Laubli, N. F.; Scherer, K. M.; Avezov, E.; Lio, P.; Lapkin, A. A.; Kaminski Schierle, G. S.; Kaminski, C. F.
10.1101/2022.05.17.492189 — bioengineering — Posted on 2022-05-18
1861 Genome dynamics in mosses: Extensive synteny coexists with a highly dynamic gene space
Kirbis, A.; Rahmatpour, N.; Dong, S.; Yu, J.; van Gessel, N.; Waller, M.; Reski, R.; Lang, D.; Rensing, S. A.; Temsch, E.; Wegrzyn, J. L.; Goffinet, B.; Liu, Y.; szoevenyi, p.
10.1101/2022.05.17.492078 — genomics — Posted on 2022-05-18
1863 Skewness in bee and flower phenological distributions
Stemkovski, M.; Dickson, R. G.; Griffin, S. R.; Inouye, B. D.; Inouye, D. W.; Pardee, G. L.; Underwood, N.; Irwin, R. E.
10.1101/2022.05.17.492369 — ecology — Posted on 2022-05-18
1866 A deeply conserved protease, acylamino acid-releasing enzyme (AARE), acts in plant aging
Hoernstein, S. N. W.; Oezdemir, B.; van Gessel, N.; Miniera, A. A.; Rogalla von Bieberstein, B.; Nilges, L.; Schweikert Farinha, J.; Komoll, R.; Glauz, S.; Weckerle, T.; Scherzinger, F.; Rodriguez-Franco, M.; Mueller-Schuessele, S. J.; Reski, R.
10.1101/2022.05.18.492440 — plant biology — Posted on 2022-05-18
1867 SARS-CoV-2 Subunit Virus-Like Vaccine Demonstrates High Safety Profile and Protective Efficacy: Preclinical Study
Vakhrusheva, A. V.; Kudriavtsev, A. V.; Kryuchkov, N. A.; Deev, R. V.; Frolova, M. E.; Blagodatskikh, K. A.; Djonovic, M.; Nedorubov, A. A.; Odintsova, E.; Ivanov, A. V.; Romanovskaya-Romanko, E. A.; Stukova, M. A.; Isaev, A. A.; Krasilnikov, I. V.
10.1101/2022.05.18.492452 — pharmacology and toxicology — Posted on 2022-05-18
1869 Substrate adhesion determines migration during mesenchymal cell condensation in chondrogenesis
Casanellas, I.; Jiang, H.; David, C. M.; Vida, Y.; Perez-Inestrosa, E.; Samitier, J.; Lagunas, A.
10.1101/2022.05.17.492260 — biophysics — Posted on 2022-05-18
1871 Adaptation-proof SARS-CoV-2 vaccine design
Vishweshwaraiah, Y. L.; Hnath, B.; Rackley, B.; Wang, J.; Gontu, A.; Chandler, M.; Afonin, K. A.; Kuchipudi, S. V.; Christensen, N.; Yennawar, N. H.; Dokholyan, N. V.
10.1101/2022.05.17.492310 — bioengineering — Posted on 2022-05-18
1876 Parallel measurement of transcriptomes and proteomes from same single cells using nanodroplet splitting
Fulcher, J. M.; Markillie, L. M.; Mitchell, H. D.; Williams, S. M.; Engbrecht, K. M.; Moore, R. J.; Cantlon-Bruce, J.; Bagnoli, J. W.; Seth, A.; Pasa-Tolic, L.; Zhu, Y.
10.1101/2022.05.17.492137 — systems biology — Posted on 2022-05-18
1877 Thermopriming-associated proteome and sugar content responses in Pinus radiata embryogenic tissue
Castander-Olarieta, A.; Pereira, C.; Mendes, V.; Correia, S.; Manadas, B.; Canhoto, J.; Montalban, I. A.; Moncalean, P.
10.1101/2022.05.17.492240 — plant biology — Posted on 2022-05-18
1878 Selenocysteine metabolism is a targetable vulnerability in MYCN-amplified cancers
Alborzy, H.; Chen, Z.; Yildiz, U.; Porto- Freitas, F.; Vogel, F. C. E.; Varga, J.; Batani, J.; Bartenhagen, C.; Schmitz, W.; Buechel, G.; Michalke, B.; Zheng, J.; Meierjohann, S.; Girardi, E.; Espinet, E.; Florez, A.; dos Santos, A. F.; Aroua, N.; Schlicker, L.; Xavier da Silva, T. N.; Przybylla, A.; Zeisberger, P.; Superti-Furga, G.; Eilers, M.; Conrad, M.; Fischer, M.; Schulze, A.; Trumpp, A.; Friedmann Angeli, J. P.
10.1101/2022.05.17.492172 — cancer biology — Posted on 2022-05-18
1883 The vestibular calyceal junction is dismantled in response to diverse injuring stimuli in rats and humans
Maroto, A. F.; Borrajo, M.; Callejo, A.; Amilibia, E.; Perez-Grau, M.; Roca-Ribas, F.; Castellanos, E.; Barrallo-Gimeno, A.; Llorens, J.
10.1101/2022.05.17.492294 — neuroscience — Posted on 2022-05-18
1885 Improvement of sensory deficits in Fragile X mice by increasing cortical interneuron activity after the critical period
Kourdougli, N.; Suresh, A.; Liu, B.; Juarez, P.; Lin, A.; Chung, D. T.; Graven Sams, A.; Gandal, M.; Martinez-Cerdeno, V.; Buonomano, D.; Hall, B.; Mombereau, C.; Portera-Cailliau, C.
10.1101/2022.05.17.492368 — neuroscience — Posted on 2022-05-18
1887 Astrocytes regulate inhibition in Fragile X Syndrome
Rais, M.; Kulinich, A. O.; Wagner, V.; Woodard, W.; Shuai, X. S.; Suley, S. N.; Kokash, J.; Piepponen, T. P.; Castren, M.; Razak, K.; Ethell, I.
10.1101/2022.02.08.479618 — neuroscience — Posted on 2022-05-18
1888 Minian: An open-source miniscope analysis pipeline
Dong, Z.; Mau, W.; Feng, Y.; Pennington, Z. T.; Chen, L.; Zaki, Y.; Rajan, K.; Shuman, T.; Aharoni, D.; Cai, D. J.
10.1101/2021.05.03.442492 — neuroscience — Posted on 2022-05-18
1890 Maintaining a stable head direction representation in naturalistic visual environments
Haberkern, H.; Chitnis, S. S.; Hubbard, P. M.; Goulet, T.; Hermundstad, A. M.; Jayaraman, V.
10.1101/2022.05.17.492284 — neuroscience — Posted on 2022-05-18
1892 Short-term monocular deprivation boosts neural responsiveness to audio-visual events for the undeprived eye
Federici, A.; Bernardi, G.; Senna, I.; Fantoni, M.; Ernst, M. O.; Ricciardi, E.; Bottari, D.
10.1101/2022.05.17.492319 — neuroscience — Posted on 2022-05-18
1893 Intermittent systemic exposure to lipopolysaccharide-induced inflammation disrupts hippocampal long-term potentiation and impairs cognition in aging male mice
Engler-Chiurazzi, E. B.; Russell, A. E.; Povroznik, J. M.; McDonald, K. O.; Porter, K.; Wang, D.; Billig, B.; Felton, C.; Hammock, J.; Schreurs, B. G.; O'Callghan, J.; Zwezdaryk, K.; Simpkins, J. W.
10.1101/2022.05.18.491827 — neuroscience — Posted on 2022-05-18
1894 Benefits of global mutant huntingtin lowering diminish over time in a Huntington's disease mouse model
Marchionini, D. M.; Liu, J.-P.; Ambesi-Impiombato, A.; Cox, K.; Cirillo, K.; Bansal, M.; Mushlin, R.; Brunner, D.; Ramboz, S.; Kwan, M.; Kuhlbrodt, K.; Tillack, K.; Peters, F.; Rauhala, L.; Obenauer, J.; Greene, J. R.; Hartle, C.; Khetarpal, V.; Lager, B.; Rosinski, J.; Aaronson, J.; Alam, M.; Signer, E.; Munoz-Sanjuan, I.; Howland, D.; Zeitlin, S. O.
10.1101/2022.05.17.492356 — neuroscience — Posted on 2022-05-18
1895 Two snakebite antivenoms have potential to reduce Eswatini's dependency upon a single, increasingly unavailable product: results of preclinical efficacy testing
Menzies, S. K.; Litschka-Koen, T.; Edge, R. J.; Alsolaiss, J.; Crittenden, E.; Hall, S. R.; Westhorpe, A.; Thomas, B.; Murray, J.; Shongwe, N.; Padidar, S.; Lalloo, D. G.; Casewell, N. R.; Pons, J.; Harrison, R. A.
10.1101/2022.05.16.492230 — pharmacology and toxicology — Posted on 2022-05-18
1896 Structure of the human FERRY Rab5 effector complex
Quentin, D.; Schuhmacher, J.; Klink, B. U.; Lauer, J.; Shaikh, T.; Huis in 't Veld, P. J.; Welp, L. M.; Urlaub, H.; Zerial, M.; Raunser, S.
10.1101/2021.06.21.449265 — biochemistry — Posted on 2022-05-18
1897 Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF
Corbeski, I.; Guo, X.; Eckhardt, B. V.; Fasci, D.; Wiegant, W. W.; Graewert, M.; Vreeken, K.; Wienk, H.; Svergun, D. I.; Heck, A. J. R.; van Attikum, H.; Boelens, R.; Sixma, T. K.; Mattiroli, F.; van Ingen, H.
10.1101/2021.12.24.474097 — biochemistry — Posted on 2022-05-18
1899 Starburst amacrine cells amplify optogenetic visual restoration through gap junctions in the murine retina
Katada, Y.; Kunimi, H.; Serizawa, N.; Lee, D.; Kobayashi, K.; Okano, H.; Tanaka, K. F.; Tsubota, K.; Kurihara, T.
10.1101/2020.08.11.246686 — neuroscience — Posted on 2022-05-18
1900 Botrytis cinerea infection accelerates ripening and cell wall disassembly to promote disease in tomato fruit
Silva, C.; Adaskaveg, J. A.; Mesquida-Pesci, S. D.; Ortega-Salazar, I.; Pattathil, S.; Zhang, L.; Hahn, M. G.; van Kan, J. A. L.; Cantu, D.; Powell, A.; Blanco-Ulate, B.
10.1101/2022.05.16.492169 — plant biology — Posted on 2022-05-18
1903 Interactive Neurorobotics: Behavioral and Neural Dynamics of Agent Interactions
Leonardis, E. J.; Breston, L.; Lucero-Moore, R.; Sena, L.; Kohli, R.; Schuster, L.; Barton-Gluzman, L.; Quinn, L. K.; Wiles, J.; Chiba, A.
10.1101/2022.05.17.492233 — animal behavior and cognition — Posted on 2022-05-18
1906 Modulation of Spindle Assembly Checkpoint efficiency by cell fate in a chordate embryo
Roca, M.; Besnardeau, L.; Christians, E.; McDougall, A.; Chenevert, J.; Castagnetti, S.
10.1101/2022.05.18.492463 — cell biology — Posted on 2022-05-18
1908 Late-onset glaucoma in Yap conditional knockout mouse
BITARD, J.; Grellier, E.; Lourdel, S.; Prior Filipe, H.; Hamon, A.; Fenaille, F.; Castelli, F. A.; Chu-Van, E.; Roger, J. E.; Locker, M.; Perron, M.
10.1101/2022.05.16.492143 — neuroscience — Posted on 2022-05-18
1910 Evolution of a Plastic Surgery Summer Research Program
Rabbani, P. S.; Alfonso, A. R.; Berman, Z. P.; Diep, G. K.; Lee, J.; Ramly, E. P.; Diaz Siso, J. R.; Rodriguez, E. D.
10.1101/2022.05.16.492191 — scientific communication and education — Posted on 2022-05-18
1912 Integration of multi-omics data shows downregulation of mismatch repair, purin, and tublin pathways in AR-negative triple-negative chemotherapy-resistant breast tumors
Tang, X.; Thompson, K. J.; Kalari, K. R.; Sinnwell, J. P.; Suman, V.; Vedell, P. T.; McLaughlin, S. A.; Northfelt, D. W.; Moreno Aspitia, A.; Gray, R. J.; Carter, J. M.; Weinshilboum, R.; Wang, L.; Boughey, J. C.; Goetz, M. P.
10.1101/2022.05.16.492190 — cancer biology — Posted on 2022-05-18
1916 Adaptation to ER-stress via serine glycine metabolism licences STING signalling and CMV control in intestinal epithelial cells
Wottawa, F.; Becker, B.; Bakr, M.; Mayr, L.; Kugler, J.; Windross, S. J.; Neises, L.; van den Bossche, S.; Kakavand, N.; Tran, F.; Welz, L.; Schwaerzler, J.; Banki, Z.; Stengel, S. T.; Ito, G.; Coleman, O.; Jaeger, C.; Koncina, E.; Letellier, E.; Haller, D.; Paludan, S. R.; Blumberg, R.; Kaser, A.; Cicin-Sain, L.; Schreiber, S.; Adolph, T.; Rosenstiel, P.; Meiser, J.; Aden, K.
10.1101/2022.05.17.492340 — cell biology — Posted on 2022-05-18
1917 Therapeutic neutralizing monoclonal antibody administration protects against lethal viscerotropic Yellow Fever infection
Ricciardi, M. J.; Rust, L. N.; Pedreno-Lopez, N.; Yusova, S.; Biswas, S.; Webb, G. M.; Fischer, M.; Gonsales-Nieto, L.; Voigt, T. B.; Louw, J. J.; Laurino, F. D.; DiBello, J. R.; Raue, H.-P.; Raphael, L. M. S.; Yrizarry-Medina, A.; Rosen, B. C.; Agnor, R.; Gao, L.; Labriola, C.; Axthelm, M.; Smedley, J.; Julander, J. G.; Bonaldo, M. C.; Walker, L. M.; Slifka, M. K.; Messaoudi, I.; Burton, D. R.; Kallas, E. G.; Sacha, J. B.; Watkins, D. I.; Burwitz, B. J.
10.1101/2022.05.16.491863 — immunology — Posted on 2022-05-18
1918 TOB is an effector of the hippocampus-mediated acute stress response
Youssef, M. M. M.; Hamada, H. T.; Lai, E. S. K.; Kiyama, Y.; EL Tabbal, M.; Kiyonari, H.; Nakano, K.; Kuhn, B.; Yamamoto, T.
10.1101/2022.05.16.492218 — neuroscience — Posted on 2022-05-18
1919 Ptr1 and ZAR1 immune receptors confer overlapping and distinct bacterial pathogen effector specificities
Ahn, Y. J.; Kim, H.; Choi, S.; Mazo-Molina, C.; Prokchorchik, M.; Zhang, N.; Kim, B.; Mang, H.; Yoon, H.; Segonzac, C.; Martin, G.; Schultink, A.; Sohn, K. H.
10.1101/2022.05.16.492216 — plant biology — Posted on 2022-05-18
1920 The gradient-based parameter optimization to determine membrane ionic current composition of human induced pluripotent stem cell-derived cardiomyocytes
Kohjitani, H.; Koda, S.; Himeno, Y.; Makiyama, T.; Yamamoto, Y.; Yoshinaga, D.; Wuriyanghai, Y.; Kashiwa, A.; Toyoda, F.; Zhang, Y.; Amano, A.; Noma, A.; Kimura, T.
10.1101/2022.05.16.492203 — physiology — Posted on 2022-05-18
1922 MFGE8 links absorption of dietary fatty acids with catabolism of enterocyte lipid stores through HNF4 γ- dependent transcription of CES enzymes
Datta, R.; Gholampour, M. A.; Yang, C. D.; Volk, R.; Lin, S.; Podolsky, M. J.; Arnold, T.; Rieder, F.; Zaro, B. W.; Verzi, M.; Lehner, R.; Abumrad, N.; Lizama, C. O.; Atabai, K.
10.1101/2022.05.16.492147 — physiology — Posted on 2022-05-18
1923 Two snakebite antivenoms have potential to reduce Eswatini's dependency upon a single, increasingly unavailable product: results of preclinical efficacy testing
Menzies, S. K.; Litschka-Koen, T.; Edge, R. J.; Alsolaiss, J.; Crittenden, E.; Hall, S. R.; Westhorpe, A.; Thomas, B.; Murray, J.; Shongwe, N.; Padidar, S.; Lalloo, D. G.; Casewell, N. R.; Pons, J.; Harrison, R. A.
10.1101/2022.05.16.492230 — pharmacology and toxicology — Posted on 2022-05-18
1925 Quantifying Visual Acuity for Pre-Clinical Testing of Visual Prostheses.
Spencer, M. J.; Kameneva, T.; Grayden, D. B.; Burkitt, A. N.; Meffin, H.
10.1101/2022.05.16.492214 — bioengineering — Posted on 2022-05-18
1926 Domestication in dry-cured meat Penicillium fungi: convergent specific phenotypes and horizontal gene transfers without strong genetic subdivision
Lo, Y.-C.; Bruxaux, J.; Rodriguez de la Vega, R. C.; Snirc, A.; Coton, M.; Le Piver, M.; Le Prieur, S.; Roueyre, D.; Dupont, J.; Houbraken, J.; Debuchy, R.; Ropars, J.; Giraud, T.; Branca, A.
10.1101/2022.03.25.485132 — evolutionary biology — Posted on 2022-05-18
1927 Protective geometry and reproductive anatomy as candidate determinants of clutch size variation in pentatomid bugs
Abram, P. K.; Guerra-Grenier, E.; Brodeur, J.; Capko, C.; Aquino, M. F. S.; Beers, B.; Blassioli-Moraes, M. C.; Borges, M.; Cingolani, M. F.; Cusumano, A.; DeClercq, P.; Fernandez, C. A.; Gariepy, T. D.; Haye, T.; Hoelmer, K.; Laumann, R. A.; Lietti, M.; McPherson, J. E.; Punschke, E.; Saunders, T. E.; Zhang, J. P.; Hardy, I. C. W.
10.1101/2022.05.16.492197 — ecology — Posted on 2022-05-18
1928 An algorithm for the identification of indicator taxonomic units and their use in analyses of ecosystem state
de la Vega, H.; Falco, L. B.; Saravia, L. A.; Sandler, R. V.; Duhour, A.; Velazco, V. N.; Coviella, C. E.
10.1101/2022.05.16.492087 — ecology — Posted on 2022-05-18
1930 Re-direction of phagosomes to the recycling expulsion pathway by a fungal pathogen
Jia, L.; Rafiq, M.; Radosa, L.; Hortschansky, P.; Cunha, C. A.; Cseresnyes, Z.; Krueger, T.; Schmidt, F.; Heinekamp, T.; Strassburger, M.; Loeffler, B.; Doenst, T.; Lacerda, J. F.; Campos, A.; Figge, M. T.; Carvalho, A.; Kniemeyer, O.; Brakhage, A. A.
10.1101/2022.05.18.492126 — cell biology — Posted on 2022-05-18
1931 Anthrax intoxication reveals that ER-Golgi membrane contact sites control the formation of plasma membrane lipid nanodomains
Anwar, M. U.; Sergeeva, O. A.; Abrami, L.; Mesquita, F.; Lukonin, I.; Amen, T.; Chuart, A.; Capolupo, L.; Liberali, P.; D'Angelo, G.; van der Goot, F. G.
10.1101/2022.05.18.492252 — cell biology — Posted on 2022-05-18
1932 Inactivation of Vascular Stem Cells Suppresses Intimal Hyperplasia in Vein Grafts
Cui, T.; Wu, W.; Zang, H.; Qi, L.; Nagarkatti, M.; Nagarkatti, P.; Garcia, I.; Evans, M. C. M. W.
10.1101/2022.05.17.492289 — cell biology — Posted on 2022-05-18
1933 Mindin differentially regulates fibroblast subpopulations via distinct members of the Src family kinases during fibrogenesis.
Kataria, S.; Rana, I.; Badarinath, K.; Zaarour, R. F.; Zirmire, R.; Dam, B.; Kumar, P.; Gulyani, A.; Jamora, C.
10.1101/2022.05.17.492347 — cell biology — Posted on 2022-05-18
1935 High-fidelity optical diffraction tomography of live organisms using non-toxic tunable refractive index media
Lee, D.; Lee, M.; KWAK, H.; Kim, Y.; Shim, J.; Jung, J. H.; Park, W.-S.; Park, J.-H.; Lee, S.; Park, Y.
10.1101/2022.05.18.492426 — cell biology — Posted on 2022-05-18
1936 Volume-transmitted GABA waves pace epileptiform rhythms in the hippocampal network
Magloire, V.; Savtchenko, L. P.; Sylantyev, S.; Jensen, T. P.; Cole, N.; Marvin, J. S.; Looger, L. L.; Kullmann, D. M.; Walker, M. C.; Pavlov, I.; Rusakov, D. A.
10.1101/2021.03.25.437016 — neuroscience — Posted on 2022-05-18
1937 Carbapenem heteroresistance of KPC-producing Klebsiella pneumoniae results from tolerance, persistence and resistance.
Chiarelli, A.; Cabanel, N.; Rosinski-Chupin, I.; Obadia, T.; Ruimy, R.; Naas, T.; Bonnin, R.; Glaser, P.
10.1101/2022.05.03.490393 — microbiology — Posted on 2022-05-18
1938 Preclinical Efficacy of IMM-BCP-01, a Highly Active Patient-Derived Anti-SARS-CoV-2 Antibody Cocktail
Nikitin, P. A.; DiMuzio, J. M.; Dowling, J. P.; Patel, N. B.; Bingaman-Steele, J. L.; Nicolescu, C.; Heimbach, B. C.; Henriquez, N.; Sikorsky, E. L.; Polley, A.; Howanski, R. J.; Nath, M.; Shukla, H.; Scheaffer, S. M.; Finn, J. P.; Liang, L.-f.; Smith, T.; Storm, N.; McKay, L. G. A.; Johnson, R. I.; Malsick, L. E.; Honko, A. N.; Griffiths, A.; Diamond, M. S.; Sarma, P.; Geising, D. H.; Morin, M. J.; Robinson, M. K.
10.1101/2021.10.18.464900 — immunology — Posted on 2022-05-18
1941 In-vivo detection of cyclic-di-AMP in Staphylococcus aureus
Mukkayyan, N.; Poon, R.; Sander, P.; Lai, L.-Y.; Zubair-Nizami, Z.; Hammond, M.; Chatterjee, S. S.
10.1101/2022.05.16.492224 — microbiology — Posted on 2022-05-18
1944 Differential Histone-DNA Interactions Dictate Nucleosome Recognition of the Pioneer Transcription Factor Sox
Ozden, B.; Boopathi, R.; Barlas, A. B.; Lone, I. N.; Bednar, J.; Petosa, C.; Kale, S.; Hamiche, A.; Angelov, D.; Dimitrov, S.; Karaca, E.
10.1101/2021.12.07.471700 — biophysics — Posted on 2022-05-18
1947 CHIP ubiquitin ligase is involved in the nucleolar stress management
Piechota, M.; Biriczova, L.; Kowalski, K.; Szulc, N. A.; Pokrzywa, W.
10.1101/2022.05.17.492288 — cell biology — Posted on 2022-05-18
1950 Pathological changes induced by Alzheimer's brain inoculation in amyloid-beta plaque bearing mice
Lam, S.; Herard, A. S.; Boluda, S.; Petit, F.; Eddarkaoui, S.; Cambon, K.; Picq, J. L.; Buee, L.; Duyckaerts, C.; Haik, S.; Dhenain, M.
10.1101/2021.04.06.438654 — neuroscience — Posted on 2022-05-18
1952 Regulus infers signed regulatory networks in few samples from regions and genes activities
Louarn, M.; Collet, G.; Barre, E.; Fest, T.; Dameron, O.; Siegel, A.; Chatonnet, F.
10.1101/2021.08.02.454721 — bioinformatics — Posted on 2022-05-18
1953 High-density and scalable protein arrays for single-molecule proteomic studies
Aksel, T.; Qian, H.; Hao, P.; Indermuhle, P. F.; Inman, C.; Paul, S.; Chen, K.; Seghers, R.; Robinson, J. K.; De Garate, M.; Nortman, B.; Tan, J.; Hendricks, S.; Sankar, S.; Mallick, P.
10.1101/2022.05.02.490328 — bioengineering — Posted on 2022-05-18
1954 Long divergent haplotypes introgressed from wild sheep are associated with distinct morphological and adaptive characteristics in domestic sheep
Cheng, H.; Zhang, Z.; Wen, J.; Lenstra, J. A.; Heller, R.; Cai, Y.; Guo, Y.; Li, M.; Li, R.; Li, W.; He, S.; Wang, J.; Shao, J.; Song, Y.; Zhang, L.; Billah, M.; Wang, X.; Liu, M.; Jiang, Y.
10.1101/2022.05.17.492311 — evolutionary biology — Posted on 2022-05-18
1955 Whole-brain computation of cognitive versus acoustic errors in music
Bonetti, L.; Carlomagno, F.; Kliuchko, M.; Gold, B. P.; Palva, S.; Haumann, N. T.; Tervaniemi, M.; Huotilainen, M.; Vuust, P.; Brattico, E.
10.1101/2022.05.17.492262 — neuroscience — Posted on 2022-05-18
1956 The Proteomic Landscape of Genome-Wide Genetic Perturbations
Messner, C. B.; Demichev, V.; Muenzner, J.; Aulakh, S.; Röhl, A.; Herrera-DomInguez, L.; Egger, A.-S.; Kamrad, S.; Lemke, O.; Calvani, E.; Mülleder, M.; Lilley, K. S.; Kustatscher, G.; Ralser, M.
10.1101/2022.05.17.492318 — systems biology — Posted on 2022-05-18
1958 Simulating structurally variable Nuclear Pore Complexes for Microscopy
Theiss, M.; Heriche, J.-K.; Russell, C.; Helekal, D.; Soppitt, A.; Ries, J.; Ellenberg, J.; Brazma, A.; Uhlmann, V.
10.1101/2022.05.17.492295 — bioinformatics — Posted on 2022-05-17
1962 Zygotic genome activation by the totipotency pioneer factor Nr5a2
Gassler, J.; Kobayashi, W.; Gaspar, I.; Ruangroengkulrith, S.; Kuemmecke, M.; Kravchenko, P.; Zaczek, M.; Vallot, A.; Hernandez, L. G.; Rico, L. C.; Ladstaetter, S.; Tachibana, K.
10.1101/2022.05.17.492379 — developmental biology — Posted on 2022-05-17
1964 Intracellular Calcium links Milk Stasis to Lysosome Dependent Cell Death during Mammary Gland Involution
JEONG, J.; Lee, J.; Talaia, G.; Kim, W.; Song, J.; Yoo, K.; Gonzalez, D.; Athonvarangkul, D.; Shin, J.; Dann, P.; Haberman, A.; Kim, L. K.; Ferguson, S.; Choi, J.; Wysolmerski, J.
10.1101/2022.05.17.492309 — cell biology — Posted on 2022-05-17
1965 Comparison of simple RNA extraction methods for molecular diagnosis of hepatitis C virus in plasma
Hongjaisee, S.; Jabjainai, Y.; Sakset, S.; Preechasuth, K.; Ngo-Giang-Huong, N.; Khamduang, W.
10.1101/2022.05.17.492343 — molecular biology — Posted on 2022-05-17
1968 Investigating And Modeling the Factors that Effects the Performance of Genetic Circuits
Zilberzwige-Tal, S.; Fontanarrosa, P.; Bychenko, D.; Dorfan, Y.; Gazit, E.; Myers, C. J.
10.1101/2022.05.16.492150 — synthetic biology — Posted on 2022-05-17
1969 Structural insights into the mechanism of the sodium/iodide symporter (NIS)
Ravera, S.; Nicola, J. P.; Salazar de Simone, G.; Sigworth, F. J.; Karakas, E.; Amzel, L. M.; Bianchet, M. A.; Carrasco, N.
10.1101/2022.04.07.487502 — biophysics — Posted on 2022-05-17
1971 A structural basis for prion strain diversity
Manka, S. W.; Wenborn, A.; Betts, J.; Joiner, S.; Saibil, H. R.; Collinge, J.; Wadsworth, J. D.
10.1101/2022.05.17.492259 — biochemistry — Posted on 2022-05-17
1974 Activity of Tricyclic Pyrrolopyrimidine Gyrase B Inhibitor against Mycobacterium abscessus
Madani, A.; Negatu, D. A.; Marrouni, A. E.; Miller, R.; Boyce, C.; Murgolo, N.; Bungard, C. J.; Zimmerman, M.; Dartois, V. A.; Gengenbacher, M.; Olsen, D. B.; Dick, T.
10.1101/2022.05.16.492225 — microbiology — Posted on 2022-05-17
1975 Microclimate is a strong predictor of the native and invasive plant-associated soil microbiota on San Cristobal Island, Galapagos archipelago
Schoenborn, A. A.; Yannarell, S. M.; MacVicar, C. T.; Medina, N. N. B.; Markellie, L. M.; Mitchell, H.; Bonham, K. S.; Leon-Reyes, A.; Klepac-Ceraj, V.; Shank, E. A.
10.1101/2022.04.05.487164 — microbiology — Posted on 2022-05-17
1976 Liver humanized NSG-PiZ mice support the study of chronic hepatitis B virus infection and antiviral therapies
Colon-Thillet, R.; Stone, D.; Loprieno, M. A.; Klouser, L.; Roychoudhury, P.; Santo, T. K.; Xie, H.; Stensland, L.; Upham, S. L.; Pepper, G.; Huang, M.; Aubert, M.; Jerome, K. R.
10.1101/2022.05.17.492375 — microbiology — Posted on 2022-05-17
1978 Enhanced flavour profiles through radicicol induced genomic variation in S. pastorianus lager yeast
de la Cerda, R.; Thompson, G.; Zhang, P.; Hokamp, K.; Roche, F.; Carlin, S.; Vrhovsek, U.; Bond, U. M.
10.1101/2022.05.17.491830 — microbiology — Posted on 2022-05-17
1980 All Staphylococcus aureus bacteraemia strains have the potential to cause infective endocarditis: results of GWAS and experimental animal studies
Bastien, S.; Meyers, S.; Salgado-Pabon, W.; Giulieri, S.; Rasigade, J.-P.; Liesenborghs, L.; Kinney, K. J.; Couzon, F.; Martin-Simoes, P.; Le Moing, V.; Duval, X. M.; Holmes, N. E.; Bruun, N. E.; Skov, R.; Howden, B. P.; Fowler, V. G.; Verhamme, P.; Andersen, P. S.; Bouchiat, C.; Moreau, K.; Vandenesch, F.
10.1101/2022.05.16.491111 — microbiology — Posted on 2022-05-17
1982 Leishmania infection-derived extracellular vesicles drive transcription of genes involved in M2 polarization.
Emerson, L.; Gioseffi, A.; Barker, H.; Sheppe, A. E.; Morrill, J. K.; Edelmann, M. J.; Kima, P. E.
10.1101/2022.05.16.492154 — microbiology — Posted on 2022-05-17
1984 X-ray imaging of 30 year old wine grape wood reveals cumulative impacts of rootstocks on scion secondary growth and harvest index
Migicovsky, Z.; Quigley, M. Y.; Mullins, J.; Ali, T.; Swift, J. F.; Agasaveeran, A. R.; Dougherty, J. D.; Grant, B. M.; Korkmaz, I.; Malpeddi, M. R.; McNichol, E. L.; Sharp, A. W.; Harris, J. L.; Hopkins, D. R.; Jordan, L. M.; Kwasniewski, M. T.; Striegler, R. K.; Dowtin, A. L.; Stotts, S.; Cousins, P.; Chitwood, D. H.
10.1101/2022.05.17.492371 — plant biology — Posted on 2022-05-17
1988 D-2-Hydroxyglutarate dehydrogenase connects the propionate shunt to ketone body metabolism in Caenorhabditis elegans
Ponomarova, O.; Zhang, H.; Li, X.; Nanda, S.; Leland, T. B.; Fox, B. W.; Giese, G. E.; Schroeder, F. C.; Yilmaz, S. L.; Walhout, A. J. M.
10.1101/2022.05.16.492161 — biochemistry — Posted on 2022-05-17
1989 Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR complex
Gruszczyk, J.; Grandvuillemin, L.; Lai-Kee-Him, J.; Paloni, M.; Savva, C. G.; Germain, P.; Grimaldi, M.; Boulahtouf, A.; Kwong, H.-S.; Bous, J.; Ancelin, A.; Bechara, C.; Barducci, A.; Balaguer, P.; Bourguet, W.
10.1101/2022.05.17.491947 — biochemistry — Posted on 2022-05-17
1990 Serine Racemase is a Cysteine Racemase and Physiologic Down Regulator of Insulin Promoter Methylation
Roychaudhuri, R.; Gadalla, M. M.; Albacarys, L.; West, T.; Saavedra, H.; Amzel, L. M.; Snyder, S. H.
10.1101/2022.05.17.492243 — biochemistry — Posted on 2022-05-17
1992 Clonally selected lines after CRISPR/Cas editing are not isogenic
Panda, A.; Suvakov, M.; Mariani, J.; Drucker, K. L.; Park, Y. H.; Jang, Y.; Kollmeyer, T. M.; Sarkar, G.; Bae, T.; Kim, J. J.; Yoon, W. H.; Jenkins, R. B.; Vaccarino, F. M.; Abyzov, A.
10.1101/2022.05.17.492193 — genomics — Posted on 2022-05-17
1997 CRISPR/Cas9-Mediated Excision of ALS/FTD-Causing Hexanucleotide Repeat Expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro
Meijboom, K. E.; Abdallah, A.; Fordham, N. P.; Nagase, H.; Rodriguez, T.; Kraus, C.; Gendron, T. F.; Krishnan, G.; Esanov, R.; Andrade, N. S.; Rybin, M. J.; Ramic, M.; Stephens, Z. D.; Edraki, A.; Blackwood, M. T.; Kahriman, A.; Henninger, N.; Kocher, J.-P. A.; Benatar, M.; Brodsky, M. H.; Petrucelli, L.; Gao, F.-B.; Sontheimer, E. J.; Brown, R. H.; Zeier, Z.; Mueller, C.
10.1101/2022.05.17.492303 — molecular biology — Posted on 2022-05-17
1998 Spontaneous genomic variation as a survival strategy of nosocomial S. haemolyticus
Bouchami, O.; Machado, M.; Carrico, J. A.; Melo Cristino, J.; de Lencastre, H.; Miragaia, M.
10.1101/2022.05.17.492267 — microbiology — Posted on 2022-05-17
2001 In-vivo detection of cyclic-di-AMP in Staphylococcus aureus
Chatterjee, S. S.; Mukkayyan, N.; Poon, R.; Sander, P.; Hammond, M.; Lai, L.-Y.; Zubair-Nizami, Z.
10.1101/2022.05.16.492224 — microbiology — Posted on 2022-05-17
2002 Reemergence of the Murine Bacterial Pathogen Chlamydia muridarum in Laboratory Mouse Colonies
Mishkin, N.; Ricart Arbona, R. J.; Carrasco, S.; Lawton, S.; Henderson, K. S.; Momtsios, P.; Sigar, I. M.; Ramsey, K. H.; Cheleuitte-Nieves, C.; Monette, S.; Lipman, N. S.
10.1101/2022.05.16.491822 — microbiology — Posted on 2022-05-17
2005 The ATLAS™ screening assay reveals distinct CD4+ and CD8+ SARS-CoV-2 antigen response profiles which have implications to Omicron cellular immunity
Foti, J. J.; Lema, K.; Strickland, J.; Tjon, E.; Li, A.; Rivera, A.; Cabral, C.; Cormier, L.; Dowal, L.; Rao, S.; Vemulapalli, V.; Flechtner, J. B.
10.1101/2022.05.17.491668 — immunology — Posted on 2022-05-17
2006 Biocompatible polymers for scalable production of human neural organoids
Narazaki, G.; Miura, Y.; Pavlov, S. D.; Thete, M. V.; Roth, J. G.; Shin, S.; Heilshorn, S.; Pasca, S. P.
10.1101/2022.03.18.484949 — neuroscience — Posted on 2022-05-17
2009 Normative Decision Rules in Changing Environments
Barendregt, N. W.; Gold, J. I.; Josic, K.; Kilpatrick, Z. P.
10.1101/2022.04.27.489722 — neuroscience — Posted on 2022-05-17
2012 Virtual screening for small molecule pathway regulators by image profile matching
Rohban, M. H.; Fuller, A. M.; Tan, C.; Goldstein, J. T.; Syangtan, D.; Gutnick, A.; DeVine, A.; Nijsure, M. P.; Rigby, M.; Sacher, J. R.; Corsello, S. M.; Peppler, G. B.; Bogaczynska, M.; Boghossian, A.; Ciotti, G. E.; Hands, A. T.; Mekareeya, A.; Doan, M.; Gale, J. P.; Derynck, R.; Turbyville, T.; Boerckel, J. D.; Singh, S.; Kiessling, L. L.; Schwarz, T. L.; Varelas, X.; Wagner, F. F.; Kafri, R.; Eisinger-Mathason, T. S. K.; Carpenter, A. E.
10.1101/2021.07.29.454377 — bioinformatics — Posted on 2022-05-17
2014 High-density and scalable protein arrays for single-molecule proteomic studies
Aksel, T.; Qian, H.; Hao, P.; Indermuhle, P. F.; Inman, C.; Paul, S.; Chen, K.; Seghers, R.; Robinson, J. K.; De Garate, M.; Nortman, B.; Tan, J.; Hendricks, S.; Sankar, S.; Mallick, P.
10.1101/2022.05.02.490328 — bioengineering — Posted on 2022-05-17
2015 Juxtaposition of Bub1 and Cdc20 on phosphorylated Mad1 during catalytic mitotic checkpoint complex assembly
Fischer, E. S.; Yu, C. W.; Hevler, J. F.; McLaughlin, S. H.; Maslen, S. L.; Heck, A. J.; Freund, S. M.; Barford, D.
10.1101/2022.05.16.492081 — biochemistry — Posted on 2022-05-17
2016 De novo phytosterol synthesis in animals
Michellod, D.; Bien, T.; Birgel, D.; Jensen, M.; Kleiner, M.; Fearn, S.; Zeidler, C.; Gruber-Vodicka, H. R.; Dubilier, N.; Liebeke, M.
10.1101/2022.04.22.489198 — biochemistry — Posted on 2022-05-17
2017 Ants act as olfactory bio-detectors of tumour in patient-derived xenograft mice
Piqueret, B.; Montaudon, E.; Devienne, P.; Leroy, C.; Marangoni, E.; Sandoz, J.-C.; d'Ettorre, P.
10.1101/2022.05.16.492058 — animal behavior and cognition — Posted on 2022-05-17
2018 Hemin availability induces coordinated DNA methylation and gene expression changes in Porphyromonas gingivalis
Costeira, R.; Aduse-Opoku, J.; Vernon, J. J.; Rodriguez-Algarra, F.; Joseph, S.; Devine, D. A.; Marsh, P. D.; Rakyan, V.; Curtis, M. A.; Bell, J. T.
10.1101/2022.03.14.484211 — genomics — Posted on 2022-05-17
2020 Manganese is a Physiologically Relevant TORC1 Activator in Yeast and Mammals.
Nicastro, R.; Gaillard, H.; Zarzuela, L.; Peli-Gulli, M.-P.; Fernandez-Garcia, E.; Tome, M.; Garcia-Rodriguez, N.; Duran, R. V.; De Virgilio, C.; Wellinger, R. E.
10.1101/2021.12.09.471923 — cell biology — Posted on 2022-05-17
2021 The isoforms of pyruvate kinase act as nutrient sensors for the β-cell KATP channel
Foster, H. R.; Ho, T.; Potapenko, E.; Sdao, S. M.; Lewandowski, S. L.; VanDeusen, H. R.; Davidson, S. M.; Cardone, R. L.; Prentki, M.; Kibbey, R. G.; Merrins, M. J.
10.1101/2022.02.09.478817 — cell biology — Posted on 2022-05-17
2022 Relationships between pond water and tilapia skin microbiomes in aquaculture ponds in Malawi
McMurtrie, J.; Alathari, S.; Chaput, D. L.; Bass, D.; Ghambi, C.; Nagoli, J.; Delamare-Deboutteville, J.; Mohan, C. V.; Cable, J.; Temperton, B.; Tyler, C. R.
10.1101/2021.12.06.470702 — microbiology — Posted on 2022-05-17
2025 Mechanisms of speed encoding in the human middle temporalcortex measured by 7T fMRI
Gaglianese, A.; Fracasso, A.; Fernandes, F. G.; Harvey, B. M.; Dumoulin, S. O.; Petridou, N.
10.1101/2021.02.01.429141 — neuroscience — Posted on 2022-05-17
2028 Sensory experience selectively reorganizes the late component of evoked responses
Bermudez Contreras, E.; Gomez Palacio-Schjetnan, A.; Luczak, A.; Mohajerani, M. H.
10.1101/2020.09.30.321547 — neuroscience — Posted on 2022-05-17
2029 Flattening of diurnal glucocorticoid oscillations causes Cd36 and insulin-mediated obesity
Tholen, S.; Kovary, K. M.; Rabiee, A.; Bielczyk-Maczynska, E.; Yang, W.; Kraemer, F. B.; Teruel, M. N.
10.1101/2020.01.02.893081 — physiology — Posted on 2022-05-17
2031 Tissue-specific impacts of aging and genetics on gene expression patterns in humans
Yamamoto, R.; Chung, R.; Vazquez, J. M.; Sheng, H.; Steinberg, P.; Ioannidis, N.; Sudmant, P. H.
10.1101/2021.11.16.468753 — genetics — Posted on 2022-05-17
2033 The Past, Present and Future of Elephant Landscapes in Asia
de Silva, S.; Wu, T.; Thieme, A.; Weaver, A.; Johnson, J.; Nyhus, P.; Wadey, J.; Vu, T.; Mossbrucker, A.; Neang, T.; Chen, B. S.; Songer, M.; Leimgruber, P.
10.1101/2020.04.28.066548 — ecology — Posted on 2022-05-17
2036 Machine Learning Predicts Treatment Response in Bipolar & Major Depressive Disorders
Salman, M. S.; Verner, E.; Bockholt, H. J.; Fu, Z.; Misiura, M. B.; Baker, B. T.; Osuch, E.; Sui, J.; Calhoun, V. D.
10.1101/2022.05.13.491903 — neuroscience — Posted on 2022-05-17
2038 A curated human cellular microRNAome based on 196 primary cell types
Patil, A. H.; Baran, A.; Brehm, Z.; McCall, M. N.; Halushka, M. K.
10.1101/2022.05.16.492160 — genomics — Posted on 2022-05-17
2041 Retina Gap Junction Networks Facilitate Blind Denoising in Visual Hierarchy
Yue, Y.; Lun, K.; He, L.; He, G.; Zhang, S.; Ma, L.; Liu, J. K.; Tian, Y.; Du, K.; Huang, T.
10.1101/2022.05.16.491952 — neuroscience — Posted on 2022-05-17
2045 Structural disruption of BAF chromatin remodeller impairs neuroblastoma metastasis by reverting an invasiveness epigenomic program
Jimenez, C.; Antonelli, R.; Nadal-Ribelles, M.; Devis-Jauregui, L.; Latorre, P.; Sole, C.; Masanas, M.; Molero, A.; Soriano, A.; Sanchez de Toledo, J.; Llobet-Navas, D.; Roma, J.; Posas, F.; de Nadal, E.; Gallego, S.; Moreno, L.; Segura, M. F.
10.1101/2022.05.17.492122 — cancer biology — Posted on 2022-05-17
2046 Targeting advanced prostate cancer with STEAP1 chimeric antigen receptor T cell therapy
Bhatia, V.; Kamat, N. V.; Pariva, T. E.; Wu, L.-T.; Tsao, A.; Sasaki, K.; Wiest, L. T.; Zhang, A.; Rudoy, D.; Gulati, R.; Patel, R. A.; Roudier, M. P.; True, L. D.; Haffner, M. C.; Nelson, P. S.; Priceman, S. J.; Ishihara, J.; Lee, J. K.
10.1101/2022.05.16.492156 — cancer biology — Posted on 2022-05-17
2054 Post-transcriptional control of SRSF9 promotes the epithelial-to-mesenchymal transition (EMT) in colorectal cancer cells
Rao, C.; Svoboda, R. A.; Southekal, S.; Vieira, H. M.; Huisman, D. H.; Chatterjee, D.; Guda, C.; Fisher, K. W.; Anczukow, O.; Lewis, R. E.
10.1101/2022.05.16.492181 — cell biology — Posted on 2022-05-17
2055 PRR14 organizes H3K9me3-modifed heterochromatin at the nuclear lamina
Kiseleva, A. A.; Cheng, Y.-C.; Smith, C. L.; Katz, R.; Poleshko, A.
10.1101/2022.05.17.492278 — cell biology — Posted on 2022-05-17
2057 A kinetic basis for curvature sensing by septins
Shi, W.; Cannon, K. S.; Curtis, B. N.; Edelmaier, C.; Gladfelter, A. S.; Nazockdast, E.
10.1101/2022.05.16.492121 — biophysics — Posted on 2022-05-17
2059 Unsupervised outlier detection applied to SARS-CoV-2 nucleotide sequences can identify sequences of common variants and other variants of interest
Hahn, G.; Lee, S.; Prokopenko, D.; Abraham, J.; Novak, T.; Hecker, J.; Cho, M.; Khurana, S.; Baden, L. R.; Randolph, A. G.; Weiss, S. T.; Lange, C.
10.1101/2022.05.16.492178 — bioinformatics — Posted on 2022-05-17
2060 YAP promotes cell-autonomous immune responses to tackle intracellular Staphylococcus aureus in vitro
Caire, R.; Audoux, E.; Thomas, M.; Dalix, E.; Peyron, A.; Rodriguez, K.; Dickerscheit, Y.; Marotte, H.; Vandenesch, F.; Josse, J.; Laurent, F.; Verhoeven, P.
10.1101/2022.05.17.492111 — cell biology — Posted on 2022-05-17
2062 CHIP ubiquitin ligase is involved in the nucleolar stress management
Piechota, M.; Biriczova, L.; Kowalski, K.; Szulc, N. A.; Pokrzywa, W.
10.1101/2022.05.17.492288 — cell biology — Posted on 2022-05-17
2064 Kynurenic acid, a key L-tryptophan-derived metabolite, protects the heart from an ischemic damage
Bigelman, E.; Pasmanik-Chor, M.; Dassa, B.; Itkin, M.; Malitsky, S.; Dorot, O.; Pichinuk, E.; Levin-Zaidman, S.; Dezorella, N.; Abashidze, A.; Kleinberg, Y.; Keren, G.; Entin Meer, M.
10.1101/2022.05.17.492275 — cell biology — Posted on 2022-05-17
2065 Differential Evasion of Delta and Omicron Immunity and Enhanced Fusogenicity of SARS-CoV-2 Omicron BA.4/5 and BA.2.12.1 Subvariants
Qu, P.; Evans, J. P.; Faraone, J. N.; Zou, X.; Zheng, Y.-M.; Carlin, C.; Bednash, J. S.; Lozanski, G.; Mallampalli, R. K.; Saif, L. J.; Oltz, E. M.; Mohler, P. J.; Gumina, R. J.; Liu, S.-L.
10.1101/2022.05.16.492158 — microbiology — Posted on 2022-05-17
2066 Prophylactic treatment of Glycyrrhiza glabra mitigates COVID-19 pathology through inhibition of pro-inflammatory cytokines in the hamster model and NETosis.
Rizvi, Z. A.; Babele, P.; Sadhu, S.; Madan, U.; Tripathy, M. R.; Goswami, S.; Mani, S.; Kumar, S.; Awasthi, A.; Dikshit, M.
10.1101/2022.05.16.492112 — immunology — Posted on 2022-05-17
2067 SARS-CoV-2 accessory proteins ORF7a and ORF3a use distinct mechanisms to downregulate MHC-I surface expression
Arshad, N.; Laurent-Rolle, M.; Ahmed, W. S.; Hsu, J. C.-C.; Mitchell, S. M.; Pawlak, J.; Sengupta, D.; Biswas, K. H.; Cresswell, P.
10.1101/2022.05.17.492198 — immunology — Posted on 2022-05-17
2068 Assessment of 3D MINFLUX data for quantitative structural biology in cells revisited
Gwosch, K.; Balzarotti, F.; Pape, J. K.; Hoess, P.; Ellenberg, J.; Ries, J.; Matti, U.; Schmidt, R.; Sahl, S. J.; Hell, S. W.
10.1101/2022.05.13.491065 — biophysics — Posted on 2022-05-17
2070 Pathogenic TDP-43 Disrupts Axon Initial Segment Structure and Neuronal Excitability in a Human iPSC Model of ALS
Harley, P.; Neves, G.; Riccio, F.; Barcellos Machado, C.; Cheesbrough, A.; R'Bibo, L.; Burrone, J.; Lieberam, I.
10.1101/2022.05.16.492186 — neuroscience — Posted on 2022-05-17
2071 Cachd1 is a novel Frizzled- and LRP6-interacting protein required for neurons to acquire left-right asymmetric character
Powell, G. T.; Zhao, Y.; Faro, A.; Stickney, H. L.; Novellasdemunt, L.; Henriques, P.; Gestri, G.; Redhouse White, E.; Ren, J.; Lu, W.; Young, R. M.; Hawkins, T. A.; Cavodeassi, F.; Schwarz, Q.; Dreosti, E.; Raible, D. W.; Li, V. S. W.; Wright, G. J.; Jones, E. Y.; Wilson, S. W.
10.1101/2022.05.16.492129 — developmental biology — Posted on 2022-05-17
2072 An automated high-content synaptic phenotyping platform in human neurons and astrocytes reveals a role for BET proteins in synapse assembly
Berryer, M. H.; Rizki, G.; Susco, S. G.; Lam, D.; Messana, A.; Trendafilova, D.; Nathanson, A.; Karhohs, K. W.; Cimini, B. A.; Pfaff, K.; Carpenter, A. E.; Rubin, L. L.; Barrett, L. E.
10.1101/2022.05.17.492322 — neuroscience — Posted on 2022-05-17
2073 Action initiation and punishment learning differ from childhood to adolescence while reward learning remains stable
Pauli, R.; Brazil, I.; Kohls, G.; Klein-Flugge, M.; Rogers, J. C.; Dikeos, D.; Dochnal, R.; Fairchild, G.; Fernandez-Rivas, A.; Herpertz-Dahlmann, B.; Hervas, A.; Konrad, K.; Popma, A.; Stadler, C.; Freitag, C. M.; De Brito, S. A.; Lockwood, P. L.
10.1101/2022.05.05.490578 — neuroscience — Posted on 2022-05-17
2077 Chromosome-level Reference Genome Provides Insights into Divergence and Stress Adaptation of the African Oil Palm
Wang, L.; Lee, M.; Wan, Z. Y.; Bai, B.; Ye, B.; Alfiko, Y.; Ramadsyah, R.; Purwantomo, S.; Song, Z.; Suwanto, A.; Yue, G. H.
10.1101/2022.05.16.492201 — genomics — Posted on 2022-05-17
2080 SARS-CoV-2 Spike evolution influences GBP and IFITM sensitivity
Mesner, D.; Reuschl, A.-K.; Whelan, M. V. X.; Bronzovich, T.; Haider, T.; Thorne, L. G.; Towers, G. J.; Jolly, C.
10.1101/2022.03.07.481785 — microbiology — Posted on 2022-05-17
2081 Two independent loss-of-function mutations in anthocyanidin synthase homeologous genes make sweet basil all green
Gonda, I.; Abu-Abied, M.; Adler, C.; Milavski, R.; Tal, O.; Davidovich-Rikanati, R.; Faigenboim, A.; Kahane-Achinoam, T.; Shachter, A.; Chaimovitsh, D.; Dudai, N.
10.1101/2022.05.16.492104 — plant biology — Posted on 2022-05-17
2082 Isolation and characterization of fucosylated extracellular vesicles based on a novel high-throughput GlyExo-Capture technique
Li, B.; Hao, K.; Li, Z.; Ma, C.; Li, H.; Du, W.; Sun, L.; Jia, T.; Liu, A.; Li, Y.; Xu, L.; Gao, Q.; Yang, R.; Lin, C.
10.1101/2021.12.09.471505 — cancer biology — Posted on 2022-05-17
2083 Near-chromosomal de novo assembly of Bengal tiger genome reveals genetic hallmarks of apex-predation
Shukla, H.; Suryamohan, K.; Khan, A.; Mohan, K.; Perumal, R.; Mathew, O.; Menon, R.; Dixon, M. D.; Muraleedharan, M.; Kuriakose, B.; Michael, S.; Krishnakutty, S.; Zachariah, A.; Seshagiri, S.; Ramakrishnan, U.
10.1101/2022.05.14.491975 — genomics — Posted on 2022-05-17
2085 Denitrification in foraminifera has ancient origin and is complemented by associated bacteria
Woehle, C.; Roy, S.; Glock, N.; Michels, J.; Wein, T.; Weissenbach, J.; Romero, D.; Hiebenthal, C.; Gorb, S.; Schoenfeld, J.; Dagan, T.
10.1101/2021.12.27.474233 — evolutionary biology — Posted on 2022-05-17
2086 A CRISPR-screen in intestinal epithelial cells identifies novel factors for polarity and apical transport
Klee, K. M.; Hess, M. W.; Lohmüller, M.; Herzog, S.; Pfaller, K.; Müller, T.; Vogel, G. F.; Huber, L. A.
10.1101/2022.05.16.492077 — cell biology — Posted on 2022-05-17
2088 Age-associated gut microbiota impairs hippocampus-dependent memory in a vagus-dependent manner
Rei, D.; Saha, S.; Haddad, M.; Haider Rubio, A.; Perlaza, B. L.; Ungeheuer, M.-N.; Sokol, H.; Lledo, P.-M.
10.1101/2021.01.28.428594 — neuroscience — Posted on 2022-05-17
2091 Synthetic lethality between TP53 and ENDOD1
Tang, Z.; Zeng, M.; Wang, X.; Gao, C.; Yue, P.; Zang, X.; Lou, H.; Chen, J.; Mu, D.; Kong, D.; Carr, A.; Liu, C.
10.1101/2020.10.14.339309 — cancer biology — Posted on 2022-05-17
2093 A comparison of six DNA extraction protocols for 16S, ITS, and shotgun metagenomic sequencing of microbial communities
Shaffer, J. P.; Carpenter, C. S.; Martino, C. P.; Salido, R. A.; Bryant, M.; Sanders, K.; Schwartz, T.; Humphrey, G.; Swafford, A. D.; Knight, R.
10.1101/2022.03.07.483343 — microbiology — Posted on 2022-05-17
2095 3D Chromatin Structure in Chondrocytes Identifies Putative Osteoarthritis Risk Genes
Phanstiel, D. H.; Thulson, E.; Davis, E. S.; D'Costa, S.; Coryell, P. R.; Kramer, N. E.; Mohlke, K. L.; Loeser, R. F.; Diekman, B. O.
10.1101/2022.05.16.492146 — genomics — Posted on 2022-05-17
2096 Developmentally determined intersectional genetic strategies to dissect adult somatosensory circuit function
Bohic, M.; Upadhyay, A.; Keating, J. R.; Simon, R.; Briones, B.; Azadegan, C.; Romanienko, P. J.; Stuber, G. D.; Abraira, V. E.
10.1101/2022.05.16.492127 — neuroscience — Posted on 2022-05-17
2098 AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional activity in Ewings sarcoma cells
Kitagawa, T.; Kobayashi, D.; Baron, B.; Okita, H.; Miyamoto, T.; Takai, R.; Paudel, D.; Ohta, T.; Asaoka, Y.; Tokunaga, M.; Furutani-Seiki, M.; Araki, N.; Kuramitsu, Y.; Kobayashi, M.
10.1101/2022.05.16.492174 — cancer biology — Posted on 2022-05-16
2100 Aspergillus fumigatus can exhibit persistence to the fungicidal drug voriconazole
Scott, J.; Valero, C.; Mato-Lopez, A.; Donaldson, I. J.; Roldan, A.; Chown, H.; Van-Rhijn, N.; Gago, S.; Furukawa, T.; Mogorovsky, A.; Ben Ami, R.; Bowyer, P.; Osherov, N.; Fontaine, T.; Goldman, G. H.; Mellado, E.; Bromley, M.; Amich, J.
10.1101/2022.05.16.491816 — microbiology — Posted on 2022-05-16
2101 Controversy over the decline of arthropods: a matter of temporal baseline?
Duchenne, F.; Porcher, E.; Mihoub, J.-B.; Loïs, G.; Fontaine, C.
10.1101/2022.02.09.479422 — ecology — Posted on 2022-05-16
2102 Trimethylamine N-oxide reduces neurite density and plaque intensity in a murine model of Alzheimer disease
Zarbock, K. R.; Han, J. H.; Singh, A. P.; Thomas, S. P.; Bendlin, B. B.; Denu, J. M.; Yu, J.-P. J.; Rey, F. E.; Ulland, T. K.
10.1101/2022.05.15.492014 — neuroscience — Posted on 2022-05-16
2103 Neurexin and Frizzled signaling intercept axonal-transport at microtubule minus-ends to control synapse formation
Balseiro-Gomez, S.; Park, J.; Yue, Y.; Ding, C.; Shao, L.; Cetinkaya, S.; Kuzoian, C.; Hammarlund, M.; Verhey, K. J.; Yogev, S.
10.1101/2021.03.22.436477 — neuroscience — Posted on 2022-05-16
2107 Juxtaposition of Bub1 and Cdc20 on phosphorylated Mad1 during catalytic mitotic checkpoint complex assembly
Fischer, E. S.; Yu, C. W.; Hevler, J. F.; McLaughlin, S. H.; Maslen, S. L.; Heck, A. J.; Freund, S. M.; Barford, D.
10.1101/2022.05.16.492081 — biochemistry — Posted on 2022-05-16
2109 Isolation of bat sarbecoviruses of SARS-CoV-2 clade, Japan
Murakami, S.; Kitamura, T.; Matsugo, H.; Kamiki, H.; Oyabu, K.; Sekine, W.; Takenaka-Uema, A.; Sakai-Tagawa, Y.; Kawaoka, Y.; Horimoto, T.
10.1101/2022.05.16.492045 — microbiology — Posted on 2022-05-16
2112 Human Surfactant Protein D Facilitates SARS-CoV-2 Pseudotype Binding and Entry in DC-SIGN Expressing Cells, and Downregulates Spike protein Induced Inflammation
Beirag, N.; Kumar, C.; Madan, T.; Shamji, M. H.; Bulla, R.; Mitchell, D.; Murugaiah, V.; Mayora Neto, M.; Temperton, N. J.; Idicula-Thomas, S.; Varghese, P. M.; Kishore, U.
10.1101/2022.05.16.491949 — immunology — Posted on 2022-05-16
2114 Two independent loss-of-function mutations in anthocyanidin synthase homeologous genes make sweet basil all green
Gonda, I.; Abu-Abied, M.; Adler, C.; Milavski, R.; Tal, O.; Davidovich-Rikanati, R.; Faigenboim, A.; Kahane-Achinoam, T.; Chaimovitsh, D.; Dudai, N.
10.1101/2022.05.16.492104 — plant biology — Posted on 2022-05-16
2116 Mammary Tissue-Derived Extracellular Matrix Hydrogels Reveal the Role of the Irradiated Microenvironment in Breast Cancer Recurrence
Zhu, T.; Alves, S. M.; Adamo, A.; Wen, X.; Corn, K. C.; Shostak, A.; Shaub, N. D.; Hacker, B. C.; D'Amore, A.; Bardhan, R.; Rafat, M.
10.1101/2022.05.16.492117 — cancer biology — Posted on 2022-05-16
2121 Does sexual conflict contribute to the evolution of novel warning patterns?
Hausmann, A.; Freire, M.; Alfthan, S. A.; Kuo, C.-Y. M.; Linares, M.; McMillan, O.; Pardo-Diaz, C.; Salazar, C.; Merrill, R. M.
10.1101/2022.05.16.492082 — evolutionary biology — Posted on 2022-05-16
2122 Developing a predictive model for an emerging epidemic on cassava in sub-Saharan Africa
Godding, D.; Stutt, R. O. J. H.; Alicai, T.; Abidrabo, P.; Okao-Okuja, G.; Gilligan, C. A.
10.1101/2022.05.13.491768 — ecology — Posted on 2022-05-16
2123 Sex differences in coronary artery disease and diabetes revealed by scRNA-Seq and CITE-Seq of human CD4+ T cells
Saigusa, R.; Vallejo, J.; Gulati, R.; Suthahar, S. S. A.; Suryawanshi, V.; Alimadadi, A.; Makings, J.; Durant, C. P.; Freuchet, A.; Roy, P.; Ghosheh, Y.; Pandori, W.; Pattarabanjird, T.; Drago, F.; McNamara, C. A.; Shemesh, A.; Lanier, L. L.; Hedrick, C. C.; Ley, K.
10.1101/2022.05.16.491900 — immunology — Posted on 2022-05-16
2124 cGAS/STING-DEPENDENT SENSING OF ENDOGENOUS RNA
Schumann, T.; Ramon, S. C.; Schubert, N.; Mayo, M. A.; Hega, M.; Ada, S.-R.; Sydow, L.; Hajikazemi, M.; Ge, Y.; Badstübner, M.; Lienenklaus, S.; Utess, B.; Muhandes, L.; Haase, M.; Müller, L.; Schmitz, M.; Gramberg, T.; Manel, N.; Zillinger, T.; Bauer, S.; Gerbaulet, A.; Paeschke, K.; Roers, A.; Behrendt, R.
10.1101/2022.05.16.492039 — immunology — Posted on 2022-05-16
2125 Quantifying rhythmicity in perceptual reports
Tosato, T.; Rohenkohl, G.; Dowdall, J. R.; Fries, P.
10.1101/2022.05.16.492063 — neuroscience — Posted on 2022-05-16
2131 The history and organization of the Workshop on Population and Speciation Genomics
Barth, J. M. I.; Handley, S.; Kintzl, D.; Leonard, G.; Malinsky, M.; Matschiner, M.; Meyer, B. S.; Salzburger, W.; Stefka, J.; Trucchi, E.
10.1101/2022.05.14.491932 — scientific communication and education — Posted on 2022-05-16
2133 A key role of the WEE1-CDK1 axis in mediating TKI-therapy resistance in FLT3-ITD positive acute myeloid leukemia patients
Massacci, G.; Venafra, V.; Latini, S.; Bica, V.; Pugliese, G. M.; Klingelhuber, F.; Krahmer, N.; Fischer, T.; Mougiakakos, D.; Boettcher, M.; Perfetto, L.; Sacco, F.
10.1101/2022.05.16.492070 — cancer biology — Posted on 2022-05-16
2134 3D-surface reconstruction of cellular cryo-soft X-ray microscopy tomograms using semi-supervised deep learning
Dyhr, M. C. A.; Sadeghi, M.; Moynova, R.; Knappe, C.; Kepsutlu, B.; Werner, S.; Schneider, G.; McNally, J.; Noe, F.; Ewers, H.
10.1101/2022.05.16.492055 — bioinformatics — Posted on 2022-05-16
2135 JBrowse Jupyter: A Python interface to JBrowse 2
Martinez, T. D. J.; Hershberg, E.; Guo, E.; Stevens, G. J.; Diesh, C.; Xie, P.; Bridge, C.; Cain, S.; Haw, R.; Buels, R. M.; Stein, L. D.; Holmes, I. H.
10.1101/2022.05.11.491552 — bioinformatics — Posted on 2022-05-16
2137 The Limits of Molecular Signatures for Pancreatic Ductal Adenocarcinoma Subtyping
Lautizi, M.; Baumbach, J.; Weichert, W.; Steiger, K.; List, M.; Pfarr, N.; Kacprowski, T.
10.1101/2022.05.16.491983 — bioinformatics — Posted on 2022-05-16
2138 Ants act as olfactory bio-detectors of tumour in patient-derived xenograft mice
Piqueret, B.; Montaudon, E.; Devienne, P.; Leroy, C.; Marangoni, E.; Sandoz, J.-C.; d'Ettorre, P.
10.1101/2022.05.16.492058 — animal behavior and cognition — Posted on 2022-05-16
2142 Genome-wide data from medieval German Jews show that the Ashkenazi founder event pre-dated the 14th century
Waldman, S.; Backenroth, D.; Harney, E.; Flohr, S.; Neff, N. C.; Buckley, G. M.; Fridman, H.; Akbari, A.; Rohland, N.; Mallick, S.; Nistal, J. C.; Yu, J.; Barzilai, N.; Peter, I.; Atzmon, G.; Ostrer, H.; Lencz, T.; Maruvka, Y. E.; Lämmerhirt, M.; Rutgers, L. V.; Renson, V.; Prufer, K. M.; Schiffels, S.; Ringbauer, H.; Sczech, K.; Carmi, S.; Reich, D.
10.1101/2022.05.13.491805 — genetics — Posted on 2022-05-16
2143 Genomic and bioclimatic diversity of Ethiopian barley (Hordeum vulgare L.) landraces reveals vulnerability to climate change
Lakew, B. F.; Caproni, L.; Kassaw, S. A.; Miculan, M.; Seid Ahmed, J.; Grazioli, S.; Fadda, C.; Pe, M. E.; Dell'Acqua, M.
10.1101/2022.05.16.492093 — genetics — Posted on 2022-05-16
2144 Multiplexed chromatin imaging reveals predominantly pairwise long-range coordination between Drosophila Polycomb genes
Gurgo, J.; Walter, J.-C.; Fiche, J.-B.; Houbron, C.; Schaeffer, M.; Cavalli, G.; Bantignies, F.; Nollmann, M.
10.1101/2022.05.16.492046 — genetics — Posted on 2022-05-16
2145 The origin and evolution of mitochondrial tropism in Midichloria bacteria
Floriano, A. M.; Batisti Biffignandi, G.; Castelli, M.; Olivieri, E.; Clementi, E.; Comandatore, F.; Rinaldi, L.; Opara, M.; Plantard, O.; Palomar, A. M.; Noel, V.; Vijay, A.; Lo, N.; Makepeace, B. L.; Duron, O.; Jex, A.; Guy, L.; Sassera, D.
10.1101/2022.05.16.490919 — evolutionary biology — Posted on 2022-05-16
2147 Area of Habitat maps for the world's terrestrial birds and mammals
Lumbierres, M.; Dahal, P. R.; Soria, C. D.; Di Marco, M.; Butchart, S. H. M.; Donald, P. F.; Rondinini, C.
10.1101/2022.05.13.489640 — ecology — Posted on 2022-05-16
2148 Foxe1 orchestrates thyroid and lung cell lineage divergence in mouse stem cell-derived organoids
Fonseca, B. F.; Barbee, C.; Romitti, M.; Eski, S. E.; Gillotay, P.; Monteyne, D.; Perez-Morga, D.; Refetoff, S.; Singh, S. P.; Costagliola, S.
10.1101/2022.05.16.492074 — developmental biology — Posted on 2022-05-16
2149 Composition can buffer protein dynamics within liquid-like condensates.
Jelenic, S.; Bindics, J.; Czermak, P.; Pillai, B. R.; Ruer, M.; Holehouse, A. S.; Saha, S.
10.1101/2022.05.16.492059 — cell biology — Posted on 2022-05-16
2150 Parallel clonal and molecular profiling of hematopoietic stem cells using RNA barcoding
Wojtowicz, E. E.; Mistry, J.; Uzun, V.; Scoones, A.; Chin, D. V.; Kettyle, L.; Grasso, F.; Lord, A. M.; Etherington, G.; Hellmich, C.; Woll, P. S.; Belderbos, M. E.; Bowles, K. M.; Nerlov, C.; Haerty, W.; Bystrykh, L. V.; Jacobsen, S. E. W.; Rushworth, S. A.; Macaulay, I. C.
10.1101/2022.05.16.491933 — cell biology — Posted on 2022-05-16
2153 Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells
Mistry, P.; Boddupalli, C. S.; Belinsky, G.; Gans, J.; Teeple, E.; Nguyen, T.-H.; Mehta, S.; Guo, L.; Kramer, M.; Ruan, J.; Wang, H.; Davison, M.; DJ, V.; Zhang, B.; Klinger, K.; Nair, S.
10.1101/2022.05.13.491834 — immunology — Posted on 2022-05-16
2161 CITE-Viz: Replicating the Interactive Flow Cytometry Workflow in CITE-Seq
Kong, G. L.; Nguyen, T. T.; Rosales, W. K.; Panikar, A. D.; Cheney, J. H. W.; Curtiss, B. M.; Carratt, S. A.; Braun, T. P.; Maxson, J. E.
10.1101/2022.05.15.491411 — bioinformatics — Posted on 2022-05-16
2163 Ultrastructure Expansion Microscopy reveals the nanoscale cellular architecture of budding and fission yeast
Hinterndorfer, K.; Laporte, M. H.; Mikus, F.; Petrozzi, L. T.; Bourgoint, C.; Prouteau, M.; Dey, G.; Loewith, R.; Guichard, P.; Hamel, V.
10.1101/2022.05.16.492060 — cell biology — Posted on 2022-05-16
2164 No evidence for detectable direct effects of magnetic field on cellular autofluorescence
Uzhytchak, M.; Smolkova, B.; Frtus, A.; Stupakov, A.; Lunova, M.; Scollo, F.; Hof, M.; Jurkiewicz, P.; Sullivan, G. J.; Dejneka, A.; Lunov, O.
10.1101/2022.05.15.491784 — cell biology — Posted on 2022-05-16
2166 Unique gut microbiome signatures among adult patients with moderate to severe atopic dermatitis in southern Chinese
Wang, Y.; Hou, J.; Tsui, J. C.-C.; Wang, L.; Zhou, J.; Chan, U. K.; Lo, C. J. Y.; Siu, P. L. K.; Loo, S. K. F.; Tsui, S. K.-W.
10.1101/2022.05.14.491964 — microbiology — Posted on 2022-05-16
2169 Design and construction of 3D-printed devices to investigate active and passive bacterial dispersal on hydrated surfaces
Kuhn, T.; Buffi, M.; Bindschedler, S.; Chain, P.; Gonzalez, D.; Stanley, C.; Wick, L.; Junier, P.; Richter, X.-Y. L.
10.1101/2022.05.16.492069 — microbiology — Posted on 2022-05-16
2172 Juxtaposition of Bub1 and Cdc20 on phosphorylated Mad1 during catalytic mitotic checkpoint complex assembly
Fischer, E. S.; Yu, C. W.; Hevler, J. F.; McLaughlin, S. H.; Maslen, S. L.; Heck, A. J.; Freund, S. M.; Barford, D.
10.1101/2022.05.16.492081 — biochemistry — Posted on 2022-05-16
2173 Mitochondrial Phenotypes Distinguish Pathogenic MFN2 Mutations by Pooled Functional Genomics Screen
Yenkin, A. L.; Bramley, J. C.; Waligorski, J. E.; Kremitzki, C. L.; Liebeskind, M. J.; Xu, X. E.; Vakaki, M. A.; Chandrasekaran, V.; Mitra, R. D.; Milbrandt, J. D.; Buchser, W. J.
10.1101/2021.03.12.434746 — genomics — Posted on 2022-05-16
2174 Tead1 reciprocally regulates adult β-cell proliferation and function
Lee, J.; Liu, R.; Kim, B.; Zhang, Y.; Li, F.; Jagannathan, R.; Yang, P.; Negi, V.; Perez-Garcia, E. M.; Saha, P.; Sabek, O.; Coarfa, C.; Creighton, C.; Huising, M.; Shih, H. P.; Bottino, R.; Ma, K.; Moulik, M.; Yechoor, V.
10.1101/2020.03.05.979450 — molecular biology — Posted on 2022-05-16
2175 A SCID mouse model to evaluate the efficacy of antivirals against SARS-CoV-2 infection
Abdelnabi, R.; Foo, C. S.; Kaptein, S.; Boudewijns, R.; Vangeel, L.; De Jonghe, S.; Jochmans, D.; Weynand, B.; Neyts, J.
10.1101/2022.05.13.491916 — microbiology — Posted on 2022-05-16
2177 A live attenuated vaccine confers superior mucosal and systemic immunity to SARS-CoV-2 variants
Nouailles, G.; Adler, J. M.; Pennitz, P.; Peidli, S.; Teixeira Alves, G.; Baumgart, M.; Bushe, J.; Voss, A.; Langenhagen, A.; Pott, F.; Kazmierski, J.; Goekeri, C.; Simmons, S.; Xing, N.; Langner, C.; Martin Vidal, R.; Abdelgawad, A.; Herwig, S.; Cichon, G.; Niemeyer, D.; Drosten, C.; Goffinet, C.; Landthaler, M.; Blüthgen, N.; Wu, H.; Witzenrath, M.; Gruber, A. D.; Praktiknjo, S. D.; Osterrieder, N.; Wyler, E.; Kunec, D.; Trimpert, J.
10.1101/2022.05.16.492138 — immunology — Posted on 2022-05-16
2181 SARS-CoV-2 Omicron Variant Wave in India: Advent, Phylogeny and Evolution
Singh, U. B.; Deb, S.; Chaudhry, R.; Bala, K.; Rani, L.; Gupta, R.; Kumari, L.; Ahmed, J.; Gaurav, S.; Perumalla, S.; Nizam, M.; Mishra, A.; Stephenraj, J.; Shukla, J.; Bhardwaj, D.; Nayer, J.; Aggarwal, P.; Kabra, M.; Ahuja, V.; Sinha, S.; Guleria, R.
10.1101/2022.05.14.491911 — genomics — Posted on 2022-05-16
2182 Global ecological and biogeochemical impacts of pelagic tunicates
Luo, J. Y.; Stock, C. A.; Henschke, N.; Dunne, J. P.; O'Brien, T. D.
10.1101/2022.03.01.482560 — ecology — Posted on 2022-05-16
2183 Fatty Acid Synthase inhibitor TVB-3166 prevents S-acylation of the Spike protein of human coronaviruses.
Mekhail, K.; Lee, M.; Sugiyama, M.; Astori, A.; St-Germain, J.; Latreille, E.; Khosraviani, N.; Wei, K.; Lee, W. L.; Antonescu, C. N.; Raught, B.; Fairn, G. D.
10.1101/2020.12.20.423603 — cell biology — Posted on 2022-05-16
2184 A CD276/B7H3 targeted antibody drug conjugate is efficacious across multiple biomarker defined classes of metastatic prostate cancer
Agarwal, S.; Fang, L.; McGowen, K.; Yin, J.; Bowman, J.; Alilin, A. N.; Ku, A. T.; Corey, E.; Roudier, M.; True, L.; Dumpit, R.; Coleman, I.; Lee, J.; Nelson, P. S.; Senatorov, I. S.; Capaldo, B. J.; Sowalsky, A. G.; Hurt, E. M.; Kelly, K.
10.1101/2022.04.19.488784 — cancer biology — Posted on 2022-05-16
2185 The L1 Cell Adhesion Molecule Constrains Dendritic Spine Density through Ankyrin Binding in Pyramidal Neurons of the Mouse Cerebral Cortex
Murphy, K. E.; Wade, S. D.; Sperringer, J. E.; Mohan, V.; Duncan, B. W.; Pak, Y.; Lutz, D.; Schachner, M.; Maness, P. F.
10.1101/2022.05.16.492130 — neuroscience — Posted on 2022-05-16
2188 Behavioral origin of sound-evoked activity in mouse visual cortex
Bimbard, C.; Sit, T. P.; Lebedeva, A.; Reddy, C. B.; Harris, K. D.; Carandini, M.
10.1101/2021.07.01.450721 — neuroscience — Posted on 2022-05-16
2189 Rewritable Two-Dimensional DNA-Based Data Storage with Machine Learning Reconstruction
Pan, C.; Tabatabaei, S. K.; Tabatabaei Yazdi, S. M. H.; Hernandez, A. G.; Schroeder, C. M.; Milenkovic, O.
10.1101/2021.02.22.432304 — synthetic biology — Posted on 2022-05-16
2190 Mouse lemur, a new animal model to investigate cardiac pacemaker activity in primates.
DiFrancesco, M. L.; Davaze, R.; Torre, E.; Mesirca, P.; Marrot, M.; Lautier, C.; Fontes, P.; Cuoq, J.; Fernandez, A.; Lamb, N.; Pifferi, F.; Mestre Frances, N.; Mangoni, M. E.; Torrente, A. G.
10.1101/2021.10.25.465774 — physiology — Posted on 2022-05-16
2192 Deep Learning Achieves Neuroradiologist-Level Performance in Detecting Hydrocephalus Requiring Treatment
Huang, Y.; Moreno, R.; Malani, R.; Meng, A.; Swinburne, N.; Holodny, A. I.; Choi, Y.; Rusinek, H.; Golomb, J. B.; George, A.; Parra, L. C.; Young, R. J.
10.1101/2021.01.19.427328 — bioinformatics — Posted on 2022-05-16
2193 Age-associated Senescent - T Cell Signaling Promotes Type 3 Immunity that Inhibits Regenerative Response
Han, J.; Cherry, C.; Mejias, J. C.; Ruta, A.; Maestas, D. R.; Pena, A.; Nguyen, H. H.; Yang, B.; Gray-Gaillard, E.; Rutkowski, N.; Krishnan, K.; Tam, A. J.; Fertig, E. J.; Housseau, F.; Ganguly, S.; Moore, E.; Pardoll, D. M.; Elisseeff, J. H.
10.1101/2021.08.17.456641 — bioengineering — Posted on 2022-05-16
2195 Optical mapping compendium of structural variants across global cattle breeds
Talenti, A.; Powell, J.; Wragg, D.; Chepkwony, M.; Fisch, A.; Ferreira, B. R.; Marcadante, M. E. Z.; Santos, I. M.; Ezeasor, C. K.; Obishakin, E. F.; Muhanguzi, D.; Amanyire, W.; Silwamba, I.; Muma, J. B.; Mainda, G.; Kelly, R. F.; Toye, P.; Connelley, T. K.; Prendergast, J.
10.1101/2022.05.05.490773 — genomics — Posted on 2022-05-16
2201 Infection of the maternal-fetal interface and vertical transmission following low-dose inoculation of pregnant rhesus macaques (Macaca mulatta) with an African-lineage Zika virus
Koenig, M. R.; Mitzey, A. M.; Morgan, T. K.; Zeng, X.; Simmons, H. A.; Mejia, A.; Leyva Jaimes, F.; Keding, L. T.; Crooks, C. M.; Weiler, A. M.; Bohm, E. K.; Aliota, M. T.; Friedrich, T. C.; Mohr, E. L.; Golos, T. G.
10.1101/2022.05.16.492053 — pathology — Posted on 2022-05-16
2202 Ion channel model reduction using manifold boundaries
Whittaker, D. G.; Wang, J.; Shuttleworth, J.; Venkateshappa, R.; Kemp, J. M.; Claydon, T. W.; Mirams, G. R.
10.1101/2022.03.11.483794 — biophysics — Posted on 2022-05-16
2204 SARS-CoV-2 variants do not evolve to promote further escape from MHC-I recognition
Moriyama, M.; Lucas, C.; Monteiro, V. S.; Yale SARS-CoV-2 Genomic Surveillance Initiative, ; Iwasaki, A.
10.1101/2022.05.04.490614 — microbiology — Posted on 2022-05-16
2205 Human Galectin-9 Potently Enhances SARS-CoV-2 Replication and Inflammation in Airway Epithelial Cells
Du, L.; Bouzidi, M. S.; Gala, A.; Deiter, F.; Billaud, J.-N.; Yeung, S.; Dabral, P.; Jin, J.; Simmons, G.; Dossani, Z.; Niki, T.; Ndhlovu, L.; Greenland, J.; Pillai, S. K.
10.1101/2022.03.18.484956 — microbiology — Posted on 2022-05-16
2206 The spatiotemporal dynamics of recognition memory for complex versus simple auditory sequences
Fernandez Rubio, G.; Brattico, E.; Kotz, S. A.; Kringelbach, M. L.; Vuust, P.; Bonetti, L.
10.1101/2022.05.15.492038 — neuroscience — Posted on 2022-05-16
2208 Mannose metabolism inhibition sensitizes acute myeloid leukemia cells to cytarabine and FLT3 inhibitor therapy by modulating fatty acid metabolism to drive ferroptotic cell death.
Woodley, K.; Dillingh, L. S.; Giotopoulos, G.; Madrigal, P.; Rattigan, K. M.; Philippe, C.; Asby, R.; Dembitz, V.; Magee, A. S. M.; van de Lagemaat, L. N.; Mappereley, C.; James, S. C.; Tzelepis, K.; Rouault-Pierre, K.; Vassiliou, G. S.; Kranc, K. R.; Helgason, G.; Huntly, B. J. P.; Gallipoli, P.
10.1101/2022.05.16.492042 — cancer biology — Posted on 2022-05-16
2216 Adult Hox gene expression promotes periosteal stem cell maintenance and mediates reprogramming in a regionally restricted manner
Leclerc, K.; Remark, L. H.; Ramsukh, M.; Josephson, A. M.; Morgani, S.; Palma, L.; Parente, P.; Lee, S.; Muinos Lopez, E.; Leucht, P.
10.1101/2022.05.15.492027 — molecular biology — Posted on 2022-05-16
2218 A Unified Catalog of 19,251 Non-human Reference Species Genomes Provides New Insights into the Mammalian Gut Microbiomes
Li, X.; Tian, C.; Zhuang, D.; Tian, L.; Shi, X.; Bai, L.; Gao, H.; Zhou, H.; Zhao, F.; Dai, M.; Zhu, L.; Wu, Q.; Liu, X.; Zhang, T.; Sang, J.; Sahu, S. K.; Xu, X.; Jia, H.; Liu, H.; Xiao, L.; Kristiansen, K.; Zhang, Z.
10.1101/2022.05.16.491731 — microbiology — Posted on 2022-05-16
2219 Adaptive Immune Landscape of T-Cell Mediated Rejection of Human Kidney Allografts
Mueller, F. B.; Yang, H.; Li, C.; Snopkowski, C.; Dadhania, D. M.; Xiang, J. Z.; Salvatore, S.; Seshan, S. V.; Sharma, V. K.; Suthanthiran, M.; Muthukumar, T.
10.1101/2022.05.15.492021 — immunology — Posted on 2022-05-16
2222 Trimethylamine N-oxide reduces neurite density and plaque intensity in a murine model of Alzheimer disease
Zarbock, K. R.; Han, J. H.; Singh, A. P.; Thomas, S. P.; Bendlin, B. B.; Denu, J. M.; Yu, J.-P. J.; Rey, F. E.; Ulland, T. K.
10.1101/2022.05.15.492014 — neuroscience — Posted on 2022-05-16
2225 Oversharing by honey bees and the spread of viruses
Lamas, Z. S.; Ryabov, E. V.; Hawthorne, D. J.; Evans, J. D.
10.1101/2022.05.15.492017 — pathology — Posted on 2022-05-16
2228 Structural insights into bacterial sterol transport
Zhai, L.; Bonds, A.; Oo, H.; Welander, P. V.; Dassama, L. M. K.
10.1101/2022.05.15.491920 — biochemistry — Posted on 2022-05-16
2229 Predicting the HER2 status in esophageal cancer from tissue microarrays using convolutional neural networks
Pisula, J. I.; Datta, R. R.; Boerner-Valdez, L.; Avemarg, J.-R.; Jung, J.-O.; Plum, P.; Loeser, H.; Lohneis, P.; Meuschke, M.; Pinto dos Santos, D.; Gebauer, F.; Quaas, A.; Bruns, C. J.; Walch, A.; Lawonn, K.; Popp, F. C.; Bozek, K.
10.1101/2022.05.13.491769 — bioinformatics — Posted on 2022-05-16
2231 MS2Rescore: Data-driven rescoring dramatically boosts immunopeptide identification rates
Declercq, A.; Bouwmeester, R.; Hirschler, A.; Carapito, C.; Degroeve, S.; Martens, L.; Gabriels, R.
10.1101/2021.11.02.466886 — bioinformatics — Posted on 2022-05-16
2232 A potential Toxoplasma gondii lipoxygenase is necessary for virulence and associated with the host immune response
Ramirez-Flores, C. J.; Tibabuzo Perdomo, A. M.; Wilson, S. K.; Mendoza Cavazos, C.; Erazo Flores, B. J.; Barnes, K. L.; Knoll, L. J.
10.1101/2022.05.12.491751 — microbiology — Posted on 2022-05-16
2233 Nlrc4 inflammasome is critical for host protection against flagellated Salmonella
Lopez-Yglesias, A. H.; Lu, C.-C.; Lai, M. A.; Quarles, E.; Zhao, X.; Hajjar, A.; Smith, K. D.
10.1101/2022.05.13.491918 — immunology — Posted on 2022-05-16
2236 Computational modeling and quantitative cell physiology reveal central parameters for the brassinosteroid-regulated early cell physiological processes linked to elongation growth of the Arabidopsis root
Grosseholz, R.; Wanke, F.; Rohr, L.; Gloeckner, N.; Rausch, L.; Scholl, S.; Scacchi, E.; Spazierer, A.-J.; Shabala, L.; Shabala, S.; Schumacher, K.; Kummer, U.; Harter, K. J. W.
10.1101/2021.04.13.439595 — plant biology — Posted on 2022-05-16
2237 In situ cryo-electron tomography reveals the asymmetric architecture of mammalian sperm axonemes
Chen, Z.; Greenan, G. A.; Shiozaki, M.; Liu, Y.; Skinner, W. M.; Zhao, X.; Zhao, S.; Yan, R.; Guo, C.; Yu, Z.; Lishko, P. V.; Agard, D. A.; Vale, R. D.
10.1101/2022.05.15.492011 — biophysics — Posted on 2022-05-16
2240 Stable population structure in Europe since the Iron Age, despite high mobility
Antonio, M. L.; Weiss, C. L.; Gao, Z.; Sawyer, S.; Oberreiter, V.; Moots, H. M.; Spence, J. P.; Cheronet, O.; Zagorc, B.; Praxmarer, E.; Ozdogan, K. T.; Demetz, L.; Lucci, M.; Alihodzic, T.; Amrani, S.; Avetisyan, P.; Baillif-Ducros, C.; Bedic, Z.; Bertrand, A.; Bilic, M.; Bondioli, L.; Borowka, P.; Botte, E.; Burmaz, J.; Buzanic, D.; Candilio, F.; Cvetko, M.; De Angelis, D.; Drnic, I.; Elschek, K.; Fantar, M.; Gaspari, A.; Gasperetti, G.; Genchi, F.; Golubovic, S.; Hukelova, Z.; Jankauskas, R.; Vuckovic, K. J.; Jeremic, G.; Kaic, I.; Kazek, K.; Khachatryan, H.; Khudaverdyan, A.; Kirchengast,
10.1101/2022.05.15.491973 — genetics — Posted on 2022-05-16
2243 Moderate ART resistance mutations with low fitness cost in malaria parasites from Africa
Behrens, H. M.; Schmidt, S.; Peigney, D.; May, J.; Maïga-Ascofare, O.; Spielmann, T.
10.1101/2022.05.13.491767 — microbiology — Posted on 2022-05-16
2246 Quantifying dynamic facial expressions under naturalistic conditions
Jeganathan, J.; Campbell, M.; Hyett, M.; Parker, G.; Breakspear, M.
10.1101/2022.05.08.490793 — neuroscience — Posted on 2022-05-16
2257 Differential effect of Fas activation on spinal muscular atrophy motoneuron death and induction of axonal growth
Benlefki, S.; Younes, R.; Challuau, D.; Bernard-Marissal, N.; Hilaire, C.; Scamps, F.; Bowerman, M.; Kothary, R.; Schneider, B. L.; Raoul, C.
10.1101/2022.05.12.491475 — neuroscience — Posted on 2022-05-16
2260 Hecatomb: An End-to-End Research Platform for Viral Metagenomics
Roach, M. J.; Beecroft, S.; Mihindukulasuriya, K.; Wang, L.; Lima, L. F. O.; Dinsdale, E. A.; Edwards, R.; Handley, S. A.
10.1101/2022.05.15.492003 — bioinformatics — Posted on 2022-05-16
2268 Concurrent spinal and brain imaging with optically pumped magnetometers
Mardell, L. C.; ONeill, G. C.; Tierney, T. M.; Timms, R. C.; Zich, C.; Barnes, G. R.; Bestmann, S.
10.1101/2022.05.12.491623 — neuroscience — Posted on 2022-05-15
2269 DNA binding domain undergoes dynamic and selective protein-protein interactions to facilitate CTCF insulation
Rong, Z.; Kai, T.; Jie, H.; Wenjia, D.; Hongye, F.; Ying, F.; Hui, W.; Yongpeng, J.; Yuanjun, L.; Rui, W.; Jiazhi, H.; Hanhui, M.; Zhi, Q.; Xiong, J.
10.1101/2022.05.15.491938 — molecular biology — Posted on 2022-05-15
2273 PAX4 loss of function alters human endocrine cell development and influences diabetes risk
Lau, H. H.; Krentz, N.; Abaitua, F.; Perez-Alcantara, M.; Chan, J. W.; Ajeian, J.; Ghosh, S.; Champon, B.; Sun, H.; Jha, A.; Hoon, S.; Tan, N. S.; Gardner, D.; Kao, S. L.; Tai, E. S.; Gloyn, A. L.; Teo, A. K. K.
10.1101/2022.05.15.491987 — developmental biology — Posted on 2022-05-15
2275 The proto-oncogene DEK regulates neuronal excitability and tau accumulation in Alzheimer's disease vulnerable neurons
Rodriguez-Rodriguez, P.; Arroyo-Garcia, L. E.; Li, L.; Tsagkogianni, C.; Wang, W.; Salas-Allende, I.; Plautz, Z.; Cedazo-Minguez, A.; Sinha, S.; Troyanskaya, O. G.; Flajolet, M.; Yao, V.; Roussarie, J.-P.
10.1101/2022.05.14.491965 — neuroscience — Posted on 2022-05-15
2277 Chromatin-modifying enzymes as modulators of nuclear size during lineage differentiation
Meng, L.; Zatulovskiy, E.; Shibuya, Y.; Schaukowitch, K. M.; Neumayer, G.; Skotheim, J. M.; Wernig, M.
10.1101/2022.05.15.491991 — cancer biology — Posted on 2022-05-15
2278 Pan-cancer scale screening reveals NRF2 associated immunoevasive characteristics in non-small cell lung cancer and squamous malignancies
Harkonen, J.; Polonen, P.; Jawahar-Deen, A.; Selvarajan, I.; Teppo, H.-R.; Dimova, E.; Kietzmann, T.; Ahtiainen, M.; Eklund, T.; Kuopio, T.; Talvitie, E.-M.; Taimen, P.; Kallajoki, M.; Kaikkonen, M. U.; Heinaniemi, M.; Levonen, A.-L.
10.1101/2022.05.15.489654 — cancer biology — Posted on 2022-05-15
2279 High-content cellular screen image analysis benchmark study
Bray, M.; de Weck, A.; Durand, E.; Fang, J.; Gabriel, D.; Janssens, R.; Moutsatsos, I.; Spiegel, S.; Zhang, X.
10.1101/2022.05.15.491989 — bioinformatics — Posted on 2022-05-15
2280 Open Access Repository-Scale Propagated Nearest Neighbor Suspect Spectral Library for Untargeted Metabolomics
Bittremieux, W.; Avalon, N. E.; Thomas, S. P.; Kakhkhorov, S. A.; Aksenov, A. A.; Portal Gomes, P. W.; Aceves, C. M.; Caraballo Rodriguez, A. M.; Gauglitz, J. M.; Gerwick, W. H.; Jarmusch, A. K.; Kaddurah-Daouk, R. F.; Kang, K. B.; Kim, H. W.; Kondic, T.; Mannochio-Russo, H.; Meehan, M. J.; Melnik, A.; Nothias, L.-F.; O'Donovan, C.; Panitchpakdi, M.; Petras, D.; Schmid, R.; Schymanski, E. L.; van der Hooft, J. J. J.; Weldon, K. C.; Yang, H.; Zemlin, J.; Wang, M.; Dorrestein, P. C.
10.1101/2022.05.15.490691 — bioinformatics — Posted on 2022-05-15
2281 Multifunctional flexible electro-optical arrays for simultaneous spatiotemporal cardiac mapping and modulation
Obaid, S. N.; Chen, Z.; Madrid, M.; Lin, Z.; Tian, J.; Humphreys, C.; Adams, J.; Daza, N.; Balansag, J.; Efimov, I. R.; Lu, L.
10.1101/2022.05.14.491979 — bioengineering — Posted on 2022-05-15
2283 Senolytic Treatment Reduces Cell Senescence and Necroptosis in Sod1 Knockout Mice that is Associated with Reduced Inflammation and Hepatocellular Carcinoma
Thadathil, N.; Selvarani, R.; Mohammed, S. J.; Nicklas, E. H.; Tran, A. L.; Kamal, M.; Luo, W.; Brown, J. L.; Lawrence, M. M.; Borowik, A. K.; Miller, B. F.; Van Remmen, H.; Richardson, A.; Deepa, S. S.
10.1101/2022.05.15.491998 — biochemistry — Posted on 2022-05-15
2287 Detection of Borrelia garinii in the USA
Rudenko, N.; Golovchenko, M.; Horak, A.; Grubhoffer, L.; Mongodin, E. F.; Fraser, C. M.; Qiu, W.; Luft, B. J.; Morgan, R. G.; Casjens, S. R.; Schutzer, S. E.
10.1101/2022.05.15.491491 — microbiology — Posted on 2022-05-15
2289 The canonical HPA axis contributes to locomotion during photoadaptation but is not required
Lee, H. B.; Dang Thi, V. H.; Boyum, G. E.; Modhurima, R.; Hall, E. M.; Green, I. K.; Cervantes, E.; Shams, S.; Clark, K. J.
10.1101/2022.05.14.491921 — neuroscience — Posted on 2022-05-15
2293 Generating parallel representations of position and identity in the olfactory system
Taisz, I.; Dona, E.; Münch, D.; Bailey, S. N.; Morris, W. J.; Meechan, K. I.; Stevens, K. M.; Varela, I.; Gkantia, M.; Schlegel, P.; Ribeiro, C.; Jefferis, G. S. X. E.; Galili, D. S.
10.1101/2022.05.13.491877 — neuroscience — Posted on 2022-05-15
2294 Negative emotional behavior during fentanyl abstinence is mediated by adaptations in nucleus accumbens neuron subtypes
Fox, M.; Wulff, A. B.; Franco, D.; Choi, E.; Calarco, C. A.; Engeln, M.; Turner, M. D.; Chandra, R.; Rhodes, V. M.; Thompson, S. M.; Ament, S. A.; Lobo, M. K.
10.1101/2022.05.15.491856 — neuroscience — Posted on 2022-05-15
2296 An algorithmic framework for isoform-specific functional analysis
Karlebach, G.; Carmody, L.; Sundaramurthi, J. C.; Casiraghi, E.; Hansen, P.; Reese, J.; Mungall, C. J.; Valentini, G.; Robinson, P. N.
10.1101/2022.05.13.491897 — bioinformatics — Posted on 2022-05-15
2301 Intermittent fasting mitigates cognitive deficits in Alzheimer's disease via the gut-brain axis
Jia, M.; Shi, L.; Zhao, Y.; Hu, X.; Zhao, J.; Ding, C.; Shang, Y.; Li, X.; Jin, X.; Dai, X.; Liu, X.; Liu, Z.
10.1101/2022.05.11.491466 — animal behavior and cognition — Posted on 2022-05-15
2302 The lncRNA Firre functions as a transcriptional activator from a distance
Smallegan, M. J.; Much, C.; Lasda, E.; Lewandowski, J.; Rinn, J. L.
10.1101/2022.05.15.492001 — genomics — Posted on 2022-05-15
2303 Environmental selection, rather than neutral processes, best explain patterns of diversity in a tropical rainforest fish
Gates, K.; Sandoval-Castillo, J.; Brauer, C.; Unmack, P.; Laporte, M.; Bernatchez, L.; Beheregaray, L. B.
10.1101/2022.05.13.491913 — evolutionary biology — Posted on 2022-05-15
2305 Ecological Drivers of Community Cohesion
Gokhale, C. S.; Velasque, M.; Denton, J. A.
10.1101/2022.05.15.491981 — ecology — Posted on 2022-05-15
2308 The AIRE G228W mutation disturbs the interaction of AIRE with its partner molecule SIRT1
Santos, J. C.; Dametto, M.; Masson, A. P.; Faca, V. M.; Bonacin, R.; Donadi, E. A.; Passos, G. A.
10.1101/2021.08.24.457565 — immunology — Posted on 2022-05-15
2309 Transcriptomic comparison of two selective retinal cell ablation paradigms in zebrafish reveals shared and cell-specific regenerative responses
Emmerich, K. B.; Walker, S. L.; Wang, G.; White, D. T.; Wang, F.; Teng, Y.; Chunawala, Z.; Nimmagadda, S.; Saxena, M. T.; Qian, J.; Mumm, J. S.
10.1101/2020.08.04.236299 — neuroscience — Posted on 2022-05-15
2310 Active licking shapes cortical taste coding.
Neese, C.; Bouaichi, C. G.; Needham, T.; Bauer, M.; Bertram, R.; Vincis, R.
10.1101/2022.05.13.491862 — neuroscience — Posted on 2022-05-15
2311 Prediction of Stroke Outcome in Mice Based on Non-Invasive MRI and Behavioral Testing
Knab, F.; Koch, S. P.; Major, S.; Farr, T. D.; Mueller, S.; Euskirchen, P.; Eggers, M.; Kuffner, M. T. C.; Walter, J.; Dreier, J. P.; Endres, M.; Dirnagl, U.; Wenger, N.; Hoffmann, C.; Boehm-Sturm, P.; Harms, C.
10.1101/2022.05.13.491869 — neuroscience — Posted on 2022-05-15
2318 Cysteine Restriction-Specific Effects of Sulfur Amino Acid Restriction on Lipid Metabolism
Nichenametla, S. N.; Mattocks, D. A.; Cooke, D.; Midya, V.; Malloy, V. L.; Mansilla, W.; Ovrebo, B.; Turner, C.; Bastani, N. E.; Sokolova, J.; Pavlikova, M.; Richie, J. P.; Shoveller, A. K.; Refsum, H.; Olsen, T.; Vinknes, K. J.; Kozich, V.; Ables, G. P.
10.1101/2022.05.14.491847 — biochemistry — Posted on 2022-05-15
2319 Activity-based CRISPR Scanning Uncovers Allostery in DNA Methylation Maintenance Machinery
Ngan, K. C.; Hoenig, S. M.; Gosavi, P. M.; Tanner, D. A.; Lue, N. Z.; Garcia, E. M.; Lee, C.; Liau, B. B.
10.1101/2022.05.14.491958 — genomics — Posted on 2022-05-15
2321 Diverse RNA viruses associated with diatom, eustigmatophyte, dinoflagellate and rhodophyte microalgae cultures
Charon, J.; Kahlke, T.; Larsson, M. E.; Abbriano, R.; Commault, A.; Burke, J.; Ralph, P.; Holmes, E. C.
10.1101/2022.05.14.491972 — microbiology — Posted on 2022-05-15
2323 Human REM sleep controls neural excitability in support of memory formation
Lendner, J. D.; Mander, B. A.; Schuh-Hofer, S.; Schmidt, H.; Knight, R. T.; Walker, M. P.; Lin, J. J.; Helfrich, R. F.
10.1101/2022.05.13.491801 — neuroscience — Posted on 2022-05-15
2328 Flexing the principal gradient of the cerebral cortex to suit changing semantic task demands
Gao, Z.; Zheng, L.; Krieger-Redwood, K.; Halai, A.; Margulies, D. S.; Smallwood, J.; Jefferies, E.
10.1101/2022.05.14.491226 — neuroscience — Posted on 2022-05-14
2329 Aeration Strategy at Birth Does Not Impact Carotid Blood Flow and Oxygen Delivery in Preterm Lambs
Dahm, S.; Kenna, K.; Stewart, D.; Pereira-Fantini, P.; McCall, K.; Perkins, E.; Sourial, M.; Tingay, D.
10.1101/2022.03.03.482754 — physiology — Posted on 2022-05-14
2330 Wild-type IDH1 inhibition enhances chemotherapy response in melanoma
Zarei, M.; Hajihassani, O.; Hue, J. J.; Graor, H. J.; Rathore, M.; Vaziri-Gohar, A.; Asara, J. M.; Winter, J. M.; Rothermel, L. D.
10.1101/2022.05.13.491880 — cancer biology — Posted on 2022-05-14
2333 Optimization of Neuroprosthetic Vision via End-to-end Deep Reinforcement Learning
Kücükoglu, B.; Rueckauer, B.; Ahmad, N.; de Ruyter van Steveninck, J.; Güclü, U.; van Gerven, M.
10.1101/2022.02.25.482017 — bioengineering — Posted on 2022-05-14
2334 Combined Lineage Tracing and scRNA-seq Reveals Unexpected First Heart Field Predominance of Human iPSC Differentiation
Galdos, F. X.; Lee, C.; Lee, S.; Goodyer, W.; Paige, S.; Escobar, G.; Darsha, A.; Beck, A.; Xu, S.; Bak, R. O.; Porteus, M.; Wu, S. M.
10.1101/2021.09.30.462465 — developmental biology — Posted on 2022-05-14
2337 Bioengineering multifunctional extracellular vesicles for targeted delivery of biologics to T cells
Stranford, D.; Simons, L. M.; Berman, K.; Cheng, L.; Lucks, J. B.; Hultquist, J. F.; Leonard, J. N.
10.1101/2022.05.14.491879 — bioengineering — Posted on 2022-05-14
2341 The Scar/WAVE complex drives normal actin protrusions without the Arp2/3 complex, but proline-rich domains are required
Buracco, S.; Singh, S.; Claydon, S.; Paschke, P.; Tweedy, L.; Whitelaw, J.; McGarry, L.; Thomason, P. A.; Insall, R. H.
10.1101/2022.05.14.491902 — cell biology — Posted on 2022-05-14
2342 Intrinsic RNA targeting constrains the utility of CRISPR-Cas13 systems
Li, Z.; Li, Z.; Cheng, X.; Wang, X.; Ma, S.; Wang, S.; Lu, Z.; Zhang, H.; Zhao, W.; Chen, Z.; Yao, Y.; Chao, L.; Li, W.; Fei, T.
10.1101/2022.05.14.491940 — molecular biology — Posted on 2022-05-14
2345 An atrial fibrillation-associated regulatory region modulates cardiac Tbx5 levels and arrhythmia susceptibility
Bosada, F. M.; van Duijvenboden, K.; Rivaud, M. R.; Uhm, J.-S.; Verkerk, A. O.; Boukens, B. J.; Christoffels, V. M.
10.1101/2022.05.14.491627 — molecular biology — Posted on 2022-05-14
2346 A toxin-mediated policing system in Bacillus improves population fitness via penalizing non-cooperating phenotypic cheaters
Huang, R.; Shao, J.; Xu, Z.; Chen, Y.; Liu, Y.; Wang, D.; Feng, H.; Xun, W.; Shen, Q.; Zhang, N.; Zhang, R.
10.1101/2022.05.14.491907 — microbiology — Posted on 2022-05-14
2349 The Influences of Stomatal Size and Density on Rice Drought, Salinity and VPD Resilience
Caine, R. S.; Harrison, E. L.; Sloan, J. M.; Flis, P. M.; Fischer, S.; Nguyen, T. L.; Nguyen, P. T.; Gray, J. E.; Croft, H. L.
10.1101/2022.05.13.491841 — plant biology — Posted on 2022-05-14
2350 KDM4A promotes NEPC progression through regulation of MYC expression
Mak, C. S. L.; Zhu, M.; Liang, X.; Wang, F.; Hoang, A. G.; Song, X.; Shepherd, P.; Liang, D.; Park, J.; Zhang, M.; Metzger, E.; Schule, R.; Jain, A. K.; Lee, M. G.; Corn, P.; Logothetis, C. J.; Aparicio, A.; Navone, N.; Troncoso, P.; Zhang, J.; Lin, S.-H.; Wang, G.
10.1101/2022.05.14.491739 — cancer biology — Posted on 2022-05-14
2351 Exogenous DNA upregulates DUOX2 expression and function in human pancreatic cancer cells by activating the cGAS-STING signaling pathway
Wang, S. L.; Wu, Y.; Konate, M.; Lu, J.; Antony, S.; Meitzler, J. L.; Jiang, G.; Dahan, I.; Juhasz, A.; Diebold, B.; Roy, K.; Doroshow, J. H.
10.1101/2022.05.14.491678 — cancer biology — Posted on 2022-05-14
2355 LabGym: quantification of user-defined animal behaviors using learning-based holistic assessment
Hu, Y.; Ferrario, C.; Maitland, A. D.; Ionides, R. B.; Ghimire, A.; Watson, B.; Iwasaki, K.; White, H.; Xi, Y.; Zhou, J.; Ye, B.
10.1101/2022.02.17.480911 — animal behavior and cognition — Posted on 2022-05-14
2356 Transnational non-invasive monitoring and spatial capture-recapture models reveal strong effects of humans on connectivity for the Pyrenean brown bear
Kervellec, M.; Milleret, C.; Vanpe, C.; Quenette, P.-Y.; Sentilles, J.; Palazon, S.; Jordana, I. A.; Jato, R.; Elosegui Irurtia, M. M.; Gimenez, O.
10.1101/2022.05.13.491807 — ecology — Posted on 2022-05-14
2360 Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human primary intestinal epithelial cells
Bergsten, E.; Mestivier, D.; Donnadieu, F.; Pedron, T.; Tsoumtsa, L.; Lemichez, E.; Gorgette, O.; Volant, S.; Doukani, A.; Sansonetti, P. J.; Sobhani, I.; Nigro, G.
10.1101/2022.05.14.491935 — microbiology — Posted on 2022-05-14
2362 tRNA Methylation Resolves Codon Usage Bias at the Limit of Cell Viability
Masuda, I.; Yamaki, Y.; Detroja, R.; Tagore, S.; Moore, H.; Maharjan, S.; Nakano, Y.; Christian, T.; Matsubara, R.; Lowe, T. M.; Frenkel-Morgenstern, M.; Hou, Y.-M.
10.1101/2022.05.14.491930 — microbiology — Posted on 2022-05-14
2363 Nanoparticle-induced augmentation of neutrophils' phagocytosis of bacteria
Rubey, K.; Mukhitov, A. R.; Nong, J.; Wu, J.; Krymskaya, V. P.; Myerson, J. W.; Worthen, G. S.; Brenner, J. S.
10.1101/2022.05.14.491866 — immunology — Posted on 2022-05-14
2364 Distinct population and single-neuron selectivity for executive and episodic processing in human dorsal posterior cingulate
Aponik-Gremillion, L.; Chen, Y. Y.; Bartoli, E.; Koslov, S. R.; Rey, H. G.; Weiner, K. S.; Yoshor, D.; Hayden, B. Y.; Sheth, S. A.; Foster, B. L.
10.1101/2022.05.13.491864 — neuroscience — Posted on 2022-05-14
2367 Prefrontal cortex supports speech perception in listeners with cochlear implants
Sherafati, A.; Dwyer, N.; Bajracharya, A.; Hassanpour, M. S.; Eggebrecht, A. T.; Firszt, J. B.; Culver, J. P.; Peelle, J. E.
10.1101/2021.10.16.464654 — neuroscience — Posted on 2022-05-14
2368 Moderate ART resistance mutations with low fitness cost in malaria parasites from Africa
Behrens, H. M.; Schmidt, S.; Peigney, D.; May, J.; Maïga-Ascofare, O.; Spielmann, T.
10.1101/2022.05.13.491767 — microbiology — Posted on 2022-05-14
2375 Asymmetric Signaling Across the Hierarchy of Cytoarchitecture within the Human Connectome
Parkes, L.; Kim, J. Z.; Stiso, J.; Calkins, M. E.; Cieslak, M.; Gur, R. E.; Gur, R. C.; Moore, T. M.; Ouellet, M.; Roalf, D. R.; Shinohara, R. T.; Wolf, D. H.; Satterthwaite, T. D.; Bassett, D. S.
10.1101/2022.05.13.491642 — neuroscience — Posted on 2022-05-13
2376 Kidney collecting duct cells make vasopressin in response to NaCl induced hypertonicity
Arroyo, J. P.; Terker, A. S.; Zuchowski, Y.; Watts, J. A.; Bock, F.; Meyer, C.; Luo, W.; Kapp, M. E.; Gould, E. R.; Hammock, E.; Wilson, M.; Zent, R.; Zhang, M.-Z.; Bhave, G.; Harris, R. C.
10.1101/2022.05.13.491898 — physiology — Posted on 2022-05-13
2377 Age-associated Senescent - T Cell Signaling Promotes Type 3 Immunity that Inhibits Regenerative Response
Han, J.; Cherry, C.; Mejias, J. C.; Ruta, A.; Maestas, D. R.; Pena, A.; Nguyen, H. H.; Yang, B.; Gray-Gaillard, E.; Rutkowski, N.; Krishnan, K.; Tam, A. J.; Fertig, E. J.; Housseau, F.; Ganguly, S.; Moore, E.; Pardoll, D. M.; Elisseeff, J. H.
10.1101/2021.08.17.456641 — bioengineering — Posted on 2022-05-13
2378 CandyCollect: At-home saliva sampling for capture of respiratory pathogens
Lee, U. N.; Su, X.; Hieber, D. L.; Tu, W.-c.; McManamen, A. M.; Takezawa, M. G.; Hassan, G. W.; Chan, T. C.; Adams, K. N.; Wald, E. R.; DeMuri, G. P.; Berthier, E.; Theberge, A. B.; Thongpang, S.
10.1101/2021.10.19.464911 — bioengineering — Posted on 2022-05-13
2379 High-resolution simulations of chromatin folding at genomic rearrangements in malignant B-cells provide mechanistic insights on proto-oncogene deregulation
Rico, D.; Kent, D.; Karataraki, N.; Mikulasova, A.; Berlinguer-Palmini, R.; Walker, B. A.; Javierre, B. M.; Russell, L. J.; Brackley, C. A.
10.1101/2021.03.12.434963 — genomics — Posted on 2022-05-13
2382 Synonymous codon usage regulates translation initiation
Barrington, C. L.; Koch, A. L.; Galindo, G.; Larkin-Gero, E.; Morrison, E. J.; Tisa, S.; Stasevich, T.; Rissland, O.
10.1101/2022.05.13.491887 — molecular biology — Posted on 2022-05-13
2383 Coding of latent variables in sensory, parietal, and frontal cortices during virtual closed-loop navigation
Noel, J.-P.; Balzani, E.; Avila, E.; Lakshminarasimhan, K.; Bruni, S.; Alefantis, P.; Savin, C.; Angelaki, D.
10.1101/2021.10.22.465526 — neuroscience — Posted on 2022-05-13
2384 Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission
Stern, S.; Zhang, L.; Wang, M.; Wright, R.; Cordeiro, D.; Peles, D.; Hang, Y.; Mendes, A. P.; Baul, T.; Roth, J.; Coorapati, S.; Boks, M.; Pol, H. H.; Brennand, K. J.; Rethelyi, J. M.; Kahn, R. S.; Marchetto, M. C.; Gage, F. H.
10.1101/2022.05.13.491776 — neuroscience — Posted on 2022-05-13
2386 The 5-LOX/COX-2 cross-over metabolite, hemiketal E2, enhances VEGFR2 activation and promotes angiogenesis
Nakashima, F.; Gimenez-Bastida, J. A.; Luis, P. B.; Presley, S. H.; Boer, R. E.; Chiusa, M.; Shibata, T.; Sulikowski, G. A.; Pozzi, A.; Schneider, C.
10.1101/2022.05.13.491890 — pharmacology and toxicology — Posted on 2022-05-13
2387 MYC Overexpression Drives Immune Evasion in Human Cancer that is Reversible Through Restoration of Pro-Inflammatory Macrophages
Dhanasekaran, R.; Hansen, A. S.; Park, J.; Lai, I.; Adeniji, N.; Kuruvilla, S.; Suresh, A.; Swamy, V.; Felsher, D. W.
10.1101/2022.05.13.491873 — cancer biology — Posted on 2022-05-13
2388 NPC1 confers metabolic flexibility in Triple Negative Breast Cancer
O'Neill, K. I.; Kuo, L.-W.; Williams, M. M.; Lind, H. T.; Crump, L. S.; Hammond, N. G.; Spoelstra, N. S.; Caino, M. C.; Richer, J. K.
10.1101/2022.05.05.490674 — cancer biology — Posted on 2022-05-13
2390 Accurate Identification of Extrachromosomal Circular DNA from Long-read Sequences.
Wanchai, V.; Jenjaroenpun, P.; Leangapichart, T.; Arrey, G.; Burnham, C. M.; Tummle, M. C.; Delgado-Calle, J.; Regenberg, B.; Nookaew, I.
10.1101/2022.05.13.491700 — bioinformatics — Posted on 2022-05-13
2396 Moderate ART resistance mutations with low fitness cost in malaria parasites from Africa
Behrens, H. M. M.; Schmidt, S.; Peigney, D.; May, J.; Maïga-Ascofare, O.; Spielmann, T.
10.1101/2022.05.13.491767 — cell biology — Posted on 2022-05-13
2398 Reversal of splicing infidelity is a pre-activation step in B cell differentiation
O'Grady, T. M.; Baddoo, M.; Flemington, S. A.; Ungerleider, N.; Flemington, E.
10.1101/2022.05.13.491723 — immunology — Posted on 2022-05-13
2400 Blockade of TGF-β signaling reactivates HIV-1/SIV reservoirs and immune responses in vivo
Samer, S.; Thomas, Y.; Arainga, M.; Carter, C.; Shirreff, L. M.; Arif, M. S.; Avitia, J. M.; Frank, I.; McRaven, M. D.; Thuruthiyil, C. T.; Heybeli, V. B.; Anderson, M. R.; Owen, B.; Gaisin, A.; Bose, D.; Simons, L. M.; Hultquist, J. F.; Arthos, J.; Cicala, C.; Sereti, I.; Santangelo, P.; Lorenzo-Redondo, R.; Hope, T. J.; Villinger, F. J.; Marinelli, E.
10.1101/2022.05.13.489595 — immunology — Posted on 2022-05-13
2402 Mature parvalbumin interneuron function in prefrontal cortex requires activity during a postnatal sensitive period
Canetta, S. E.; Holt, E. S.; Benoit, L. J.; Teboul, E.; Sahyoun, G. M.; Ogden, R. T.; Harris, A. Z.; Kellendonk, C.
10.1101/2021.03.04.433943 — neuroscience — Posted on 2022-05-13
2406 A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1
Closa, A.; Reixachs-Sole, M.; Fuentes-Fayos, A. C.; Hayer, K. E.; Melero, J. L.; Adriaanse, F. R.; Bos, R. S.; Torres-Diz, M.; Hunger, S.; Roberts, K. G.; Mullighan, C.; Stam, R. W.; Thomas-Tikhonenko, A.; Castano, J. P.; Luque, R. M.; Eyras, E.
10.1101/2021.12.13.472370 — cancer biology — Posted on 2022-05-13
2407 Structural Basis of Mutation-Dependent p53 Tetramerization Deficiency
Rigoli, M.; Spagnolli, G.; Lorengo, G.; Monti, P.; Potestio, R.; Biasini, E.; Inga, A.
10.1101/2022.05.13.491836 — cancer biology — Posted on 2022-05-13
2408 Single-cell characterisation of the hematopoietic bone marrow interactome in health and disease
Ennis, S.; Conforte, A.; Cichocka, T.; Pal Dhami, S.; Nicholson, P.; Krebs, P.; O Broin, P.; Szegezdi, E.
10.1101/2022.05.13.491790 — cancer biology — Posted on 2022-05-13
2409 A compromise between Tgfβ and Egfr signaling programs confers the ability to lead heterogeneous collective invasion
Nasir, A.; Camacho, S.; McIntosh, A. T.; Graham, G. T.; Rahhal, R.; Huysman, M. E.; Riegel, A. T.; Pearson, G. W.
10.1101/2020.11.14.383232 — cancer biology — Posted on 2022-05-13
2410 An atlas of epithelial cell states and plasticity in lung adenocarcinoma
Han, G.; Sinjab, A.; Treekitkarnmongkol, W.; Lu, W.; Serrano, A. G.; Hernandez, S.; Rahal, Z.; Cao, X.; Dai, E.; Gomez-Bolanoz, L. I.; Parra, E. R.; Vailati Negrano, M.; Cascone, T.; Sepesi, B.; Moghaddam, S. J.; Chen, J.; Dubinett, S. M.; Scheet, P.; Fujimoto, J.; Solis, L. M.; Wistuba, I. I.; Stevenson, C.; Spira, A. E.; Wang, L.; Kadara, H.
10.1101/2022.05.13.491635 — cancer biology — Posted on 2022-05-13
2413 Concordance of MERFISH Spatial Transcriptomics with Bulk and Single-cell RNA Sequencing
Liu, J.; Tran, V.; Vemuri, V. N. P.; Byrne, A.; Borja, M.; Agarwal, S.; Wang, R.; Awayan, K.; Murti, A.; Taychameekiatchai, A.; Wang, B.; Emanuel, G.; He, J.; Haliburton, J.; Pisco, A. O.; Neff, N.
10.1101/2022.03.04.483068 — bioinformatics — Posted on 2022-05-13
2414 An integrated single-cell atlas of the skeleton from development through adulthood
Herpelinck, T.; Ory, L.; Nasello, G.; Barzegari, M.; Bolander, J.; Luyten, F. P.; Tylzanowski, P.; Geris, L.
10.1101/2022.03.14.484345 — bioinformatics — Posted on 2022-05-13
2415 A Tailored Approach To Study Legionella Infection Using Lattice Light Sheet Microscope (LLSM)
Yi, X.; Miao, H.; Lo, J. K.-Y.; Elsheikh, M.; Lee, T.-H.; Jiang, C.; Zhang, Y.; Segelke, B. W.; Overton, K. W.; Bremer, P.-T.; Laurence, T. A.
10.1101/2022.03.20.485032 — bioengineering — Posted on 2022-05-13
2416 Semi-automated protocol to quantify and characterize fluorescent, 3D vascular images
Xie, D. F.; Crouzet, C.; Lopresti, K.; Wang, Y.; Robinson, C.; Jones, W.; Muqolli, F.; Pai, A.; Fang, C.; Cribbs, D. H.; Fisher, M.; Choi, B.
10.1101/2022.05.05.490827 — bioengineering — Posted on 2022-05-13
2418 Antisense pairing and SNORD13 structure guide RNA cytidine acetylation
Thalalla Gamage, S.; Bortolin-Cavaille, M.-L.; Link, C. N.; Bryson, K. M.; Sas-Chen, A.; Schwartz, S.; Cavaille, J.; Meier, J. L.
10.1101/2022.05.12.491732 — biochemistry — Posted on 2022-05-13
2419 Arf GTPase activates the WAVE Regulatory Complex through a novel binding site
Yang, S.; Liu, Y.; Brown, A.; Schaks, M.; Ding, B.; Kramer, D. A.; Ding, L.; Alekhina, O.; Billadeau, D. D.; Chowdhury, S.; Wang, J.; Rottner, K.; Chen, B.
10.1101/2022.05.13.491857 — biochemistry — Posted on 2022-05-13
2420 Fat Body Phospholipid State Dictates Hunger Driven Feeding Behavior
Kelly, K. P.; Alassaf, M.; Sullivan, C. E.; Brent, A. E.; Goldberg, Z. H.; Poling, M. E.; Dubrulle, J.; Rajan, A.
10.1101/2021.12.16.472854 — animal behavior and cognition — Posted on 2022-05-13
2421 Predictive Models of Genome-wide Aryl Hydrocarbon Receptor DNA Binding Reveal Tissue Specific Binding Determinants
Filipovic, D.; Qi, W.; Kana, O. Z.; Marri, D.; LeCluyse, E. L.; Andersen, M. E.; Cuddapah, S.; Bhattacharya, S.
10.1101/2022.05.13.491754 — genomics — Posted on 2022-05-13
2423 Delineation and birth of a multi-layer intestinal stem cell niche
McCarthy, N.; Tie, G.; Madha, S.; Kraiczy, J.; Maglieri, A.; Shivdasani, R.
10.1101/2021.09.28.462142 — developmental biology — Posted on 2022-05-13
2424 Subcellular dynamics and functional activity of the cleaved Na+ channel β1 subunit intracellular domain
Haworth, A. S.; Hodges, S. L.; Capatina, A. L.; Isom, L. L.; Baumann, C. G.; Brackenbury, W. J.
10.1101/2021.12.29.474414 — cell biology — Posted on 2022-05-13
2425 VAP-A intrinsically disordered regions enable versatile tethering at membrane contact sites
Subra, M.; Dezi, M.; Bigay, J.; Lacas-Gervais, S.; Di Cicco, A.; Dias Araujo, A. R.; Abelanet, S.; Fleuriot, L.; Debayle, D.; Gautier, R.; Patel, A.; Roussi, F.; Antonny, B.; Levy, D.; Mesmin, B.
10.1101/2022.05.13.491839 — cell biology — Posted on 2022-05-13
2426 Vitamin K-dependent carboxylation of junctate regulates calcium flux and adaptation to metabolic stress in β-cells
Lacombe, J.; Guo, K.; Bonneau, J.; Faubert, D.; Gioanni, F.; Vivoli, A.; Muir, S. M.; Hezzaz, S.; Poitout, V.; Ferron, M.
10.1101/2022.05.13.491370 — cell biology — Posted on 2022-05-13
2427 Definition of germ layer cell lineage alternative splicing programs reveals a critical role for Quaking in specifying cardiac cell fate
Fagg, W. S.; Liu, N.; Braunschweig, U.; Pereira de Castro, K. L.; Chen, X.; Ditmars, F. S.; Widen, S. G.; Donohue, J. P.; Modis, K.; Russell, W. K.; Fair, J. H.; Weirauch, M. T.; Blencowe, B. J.; Garcia-Blanco, M. A.
10.1101/2020.12.22.423880 — molecular biology — Posted on 2022-05-13
2431 The vesicular release probability sets the strength of individual Schaffer collateral synapses
Duerst, C. D.; Wiegert, J. S.; Schulze, C.; Helassa, N.; Torok, K.; Oertner, T. G.
10.1101/2020.08.02.232850 — neuroscience — Posted on 2022-05-13
2432 Hippocampal neurons code individual episodic memories in humans
Kolibius, L. D.; Roux, F.; Parish, G. M.; ter Wal, M. J.; Van Der Plas, M.; Chelvarajah, R.; Sawlani, V.; Rollings, D.; Lang, J.; Gollwitzer, S.; Walther, K.; Hopfengaertner, R.; Kreiselmeyer, G.; Hamer, H.; Staresina, B. P.; Wimber, M.; Bowman, H.; Hanslmayr, S.
10.1101/2021.06.28.450149 — neuroscience — Posted on 2022-05-13
2433 BDNF signaling in Hebbian and Stentian structural plasticity in the developing visual system
Kutsarova, E.; Schohl, A.; Munz, M.; Wang, A.; Zhang, Y. Y.; Bilash, O. M.; Ruthazer, E. S.
10.1101/2021.10.07.463583 — neuroscience — Posted on 2022-05-13
2434 Eudicot primary cell wall glucomannan is related in synthesis, structure and function to xyloglucan
Yu, L.; Yoshimi, Y.; Cresswell, R.; Wightman, R.; Lyczakowski, J. J.; Wilson, L. F. L.; Ishida, K.; Stott, K.; Yu, X.; Charalambous, S.; Wurman-Rodrich, J.; Dupree, R.; Terrett, O. M.; Brown, S. P.; Temple, H.; Krogh, K. B. R. M.; Dupree, P.
10.1101/2022.05.11.491508 — plant biology — Posted on 2022-05-13
2435 Mass extravasation and tubular uptake of red blood cells results in toxic injury to the tubules during kidney ischemia from venous clamping
McLarnon, S. R.; Johnson, C.; Sun, J.; Wei, Q.; Csanyi, G.; O'Herron, P.; Marshall, B.; Sullivan, J. C.; Barrett, A.; O'Connor, P. M.
10.1101/2022.03.31.486613 — physiology — Posted on 2022-05-13
2436 Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response
Pagadala, M.; Wu, V. H.; Perez-Guijarro, E.; Kim, H.; Castro, A.; Talwar, J.; Sears, T.; Gonzalez-Colin, C.; Cao, S.; Schmiedel, B.; Goudarzi, S.; Kirani, D.; Salem, R.; Morris, G.; Harismendy, O.; Patel, S. P.; Mesirov, J. P.; Zanetti, M.; Day, C.-P.; Fan, C. C.; Thompson, W. K.; Merlino, G.; Gutkind, J. S.; Vijayanand, P.; Carter, H.
10.1101/2021.04.14.436660 — cancer biology — Posted on 2022-05-13
2437 Targeting the translational machinery in gastrointestinal stromal tumors (GIST) - a new therapeutic vulnerability
Lee, D. M.; Sun, A.; Patil, S. S.; Liu, L.; Rao, A. V.; Trent, P. T.; Amir, A. A.; Liu, C.; Rausch, J. L.; Presutti, L. D.; Kaczorowski, A.; Schneider, F.; Amankulor, N.; Shuda, M.; Duensing, A.
10.1101/2021.09.01.458633 — cancer biology — Posted on 2022-05-13
2438 A quantitative biophysical principle to explain the 3D cellular connectivity in curved epithelia
Gomez-Galvez, P.; Vicente-Munuera, P.; Anbari, S.; Tagua, A.; Gordillo, C.; Andres-San Roman, J. A.; Franco-Barranco, D.; Palacios, A. M.; Velasco, A.; Capitan-Agudo, C.; Grima, C.; Annese, V.; Arganda-Carreras, I.; Robles, R.; Marquez, A.; Buceta, J.; Escudero, L. M.
10.1101/2020.02.19.955567 — developmental biology — Posted on 2022-05-13
2447 Blind spots on western blots: a meta-research study highlighting opportunities to improve figures and methods reporting
Kroon, C.; Breuer, L.; Jones, L.; An, J.; Akan, A.; Ahmed Mohamed Ali, E.; Busch, F.; Fislage, M.; Ghosh, B.; Hellrigel-Holderbaum, M.; Kazezian, V.; Koppold, A.; Moreira Restrepo, C. A.; Riedel, N.; Scherschinski, L.; Urrutia Gonzalez, F. R.; Weissgerber, T. L.
10.1101/2022.05.13.491761 — cell biology — Posted on 2022-05-13
2448 Short term tomato consumption alters the pig gut microbiome towards a more favorable profile
Goggans, M. L.; Bilbrey, E. A.; Quiroz-Moreno, C. D.; Francis, D. M.; Jacobi, S. K.; Kovac, J.; Cooperstone, J. L.
10.1101/2022.05.13.489542 — microbiology — Posted on 2022-05-13
2449 Structural insights for neutralization of BA.1 and BA.2 Omicron variants by a broadly neutralizing SARS-CoV-2 antibody
Kumar, S.; Patel, A.; Lai, L.; Chakravarthy, C.; Valanparambil, R.; Davis-Gardner, M. E.; Edara, V. V.; Linderman, S.; Reddy, E. S.; Gottimukkala, K.; Nayak, K.; Bajpai, P.; Singh, V.; Frank, F.; Cheedarla, N.; Verkerke, H.; Neish, A. S.; Roback, J. D.; Mantus, G.; Goel, P. K.; Rahi, M.; Davis, C. W.; Wrammert, J.; Suthar, M. S.; Ahmed, R.; Ortlund, E.; Sharma, A.; Krishna, K. M.; Chandele, A.
10.1101/2022.05.13.491770 — immunology — Posted on 2022-05-13
2450 Post-transcriptional regulatory feedback encodes JAK-STAT signal memory of interferon stimulation
Kalliara, E.; Kardynska, M.; Bagnall, J.; Spiller, D. G.; Müller, W.; Ruckerl, D.; Biswas, S. K.; Smieja, J.; Paszek, P.
10.1101/2022.05.13.489832 — immunology — Posted on 2022-05-13
2453 Single Particle Tracking With Compressive Sensing Using Progressive Refinement Method On Sparse Recovery (spt-PRIS)
Yi, X.; Shrestha, R.; McDonald, T.; Chen, D.; Bhatia, H.; Pascucci, V.; Turbyville, T.; Bremer, P.-T.
10.1101/2022.05.13.491828 — biophysics — Posted on 2022-05-13
2454 The Smc5/6 complex is a DNA loop extruding motor
Pradhan, B.; Kanno, T.; Igarashi, M. U.; Baaske, M. D.; Wong, J. S. K.; Jeppsson, K.; Bjorkegren, C.; Kim, E.
10.1101/2022.05.13.491800 — biophysics — Posted on 2022-05-13
2456 PROPOSE: Predictive and robust probe selection for spatial transcriptomics
Covert, I.; Gala, R.; Wang, T.; Svoboda, K.; Sümbül, U.; Lee, S.-I.
10.1101/2022.05.13.491738 — cell biology — Posted on 2022-05-13
2460 Antibiotic acyldepsipeptides stimulate the Streptomyces Clp-ATPase/ClpP complex for accelerated proteolysis
Reinhardt, L.; Thomy, D.; Lakemeyer, M.; Ortega, J.; Sieber, S. A.; Sass, P.; Broetz-Oesterhelt, H.
10.1101/2022.05.13.490424 — microbiology — Posted on 2022-05-13
2461 The Human Dendritic Cell Atlas: An integrated transcriptional tool to study human dendritic cell biology
Elahi, Z.; Angel, P. W.; Butcher, S.; Rajab, N.; Choi, J.; Mintern, J.; Radford, K.; Wells, C.
10.1101/2022.05.12.491745 — immunology — Posted on 2022-05-13
2462 Humoral immunity to SARS-CoV-2 elicited by combination COVID-19 vaccination regimens
Wang, Z.; Muecksch, F.; Muenn, F.; Cho, A.; Zong, S.; Raspe, R.; Ramos, V.; Johnson, B.; Tanfous, T. B.; DaSilva, J.; Bednarski, E.; Guzman-Cardozo, C.; Tober-Lau, P.; Hillus, D.; Yao, K.; Shimeliovich, I.; Turroja, M.; Millard, K. G.; Dizon, J.; Kaczynska, A.; Gazumyan, A.; Jankovic, M.; Oliveira, T. Y.; Caskey, M.; Bieniasz, P. D.; Hatziioannou, T.; Kurth, F.; Sander, L.; Nussenzweig, M. C.; Gaebler, C.
10.1101/2022.05.13.491823 — immunology — Posted on 2022-05-13
2463 Three-doses of BNT162b2 COVID-19 mRNA vaccine establishes long-lasting CD8+ T cell immunity in CLL and MDS patients
Hernandez, S. P. A.; Hersby, D. S.; Munk, K. K.; Tamhane, T.; Trubach, D.; Tagliamonte, M.; Buonaguro, L.; Gang, A. O.; Hadrup, S. R.; Saini, S. K.
10.1101/2022.05.13.491706 — immunology — Posted on 2022-05-13
2465 Transretinal migration of astrocytes and brain/spinal cord-like cells arising from transplanted human retinal organoids.
Liu, Y.; Santiago, C.; Sogunro, A.; Konar, G. K.; Hu, M.-W.; McNally, M. M.; Lu, Y.; Li, Z.; Agakishiev, D.; Hadyniak, S.; Hussey, K.; Creamer, T. J.; Orzolek, L. D.; Teng, D.; Qian, J.; Jiang, Z.; Johnston, R. J.; Blackshaw, S.; Singh, M. S.
10.1101/2022.05.12.491655 — neuroscience — Posted on 2022-05-13
2467 Microglial P2X4 receptors promote ApoE degradation and cognitive deficits in Alzheimer disease
Jennifer, H.; Garcia de Paco, E.; Linck, N.; Maurice, T.; Desrumaux, C.; Manoury, B.; Rassendren, F.; Ulmann, L.
10.1101/2022.05.12.491601 — neuroscience — Posted on 2022-05-13
2469 Flexible perceptual encoding by discrete gamma events
Perrenoud, Q.; Fonseca, A. H. d. O.; Airhart, A.; Bonanno, J.; Mao, R.; Cardin, J. A.
10.1101/2022.05.13.491832 — neuroscience — Posted on 2022-05-13
2470 An Updated Gene Regulatory Network reconstruction of multidrug-resistant Pseudomonas aeruginosa CCBH4851
Chagas, M.; Filho, F. M.; dos Santos, M. T.; de Menezes, M. A.; Carvalho-Assef, A. P. D.; da Silva, F. A. B.
10.1101/2022.05.12.491685 — systems biology — Posted on 2022-05-13
2471 Signal peptide efficiency: from high-throughput data to prediction and explanation
Grasso, S.; Dabene, V.; Hendriks, M. M. W. B.; Zwartjens, P.; Pellaux, R.; Held, M.; Panke, S.; van Dijl, J. M.; Meyer, A.; van Rij, T.
10.1101/2022.05.13.489517 — synthetic biology — Posted on 2022-05-13
2475 Trans-generational physiological condition of embryos is conditioned by maternal thermal stress in Octopus maya
Dominguez-Castanedo, O.; Palomino-Cruz, D.; MASCARO, M. M.; Rodriguez-Fuentes, G.; Juarez, O. E.; Galindo-Sanchez, C. E. E.; Galindo-Torres, P.; Diaz, F.; Rosas, C.
10.1101/2022.05.12.491712 — physiology — Posted on 2022-05-13
2476 Hypoxic memory of tumor intrinsic type I interferon suppression promotes breast cancer metastasis
Iriondo, O.; Mecenas, D.; Li, Y.; Chin, C. R.; Thomas, A.; Amzaleg, Y.; Ortiz, V.; MacKay, M.; Dickerson, A.; Lee, G.; Harotoonian, S.; Benayoun, B. A.; Smith, A. D.; Mason, C.; Yu, M.
10.1101/2022.05.12.491632 — cancer biology — Posted on 2022-05-13
2477 Development of an antibody panel for imaging mass cytometry to investigate cancer-associated fibroblast heterogeneity and spatial distribution in archival tissues
Tornaas, S.; Kleftogiannis, D.; Fromreide, S.; Ytre-Hauge Smeland, H.; Aarstad, H. J.; Karsten Vintermyr, O.; Andreas Akslen, L.; Elena Costea, D.; Dongre, H.
10.1101/2022.05.12.491175 — cancer biology — Posted on 2022-05-13
2479 Cell-free Tumor Methylome Analysis of Small Cell Lung Cancer Patients Identifies Subgroups with Prognostic Associations
Ul Haq, S.; Schmid, S.; Aparnathi, M. K.; Hueniken, K.; Zhan, L. J.; Sacdalan, D.; Li, J. J. N.; Patel, D.; Cheng, D.; Philip, V.; Tsao, M. S.; Cabanero, M.; De Carvalho, D.; Liu, G.; Bratman, S. V.; Lok, B. H.
10.1101/2022.05.12.491321 — cancer biology — Posted on 2022-05-13
2480 Polo-like kinase-1 Inhibitors and the Antiandrogen Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling
Patterson, J. C.; Varkaris, A.; Croucher, P. J. P.; Ridinger, M.; Darlymple, S.; Nouri, M.; Xie, F.; Varmeh, S.; Jonas, O.; Whitman, M. A.; Chen, S.; Rashed, S.; Makusha, L.; Luo, J.; Isaacs, J. T.; Erlander, M. G.; Einstein, D. J.; Balk, S. P.; Yaffe, M. B.
10.1101/2022.05.12.491633 — cancer biology — Posted on 2022-05-13
2481 Development and utility of a PAK1-selective degrader
Chow, H.-Y.; Karchugina, S.; Groendyke, B. J.; Toenjes, S.; Hatcher, J.; Donovan, K. A.; Fischer, E. S.; Abalakov, G.; Faezov, B.; Dunbrack, R. L.; Gray, N. S.; Chernoff, J.
10.1101/2022.05.12.491715 — cancer biology — Posted on 2022-05-13
2482 Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer
Chaudagar, K.; Hieromnimon, H. M.; Khurana, R.; Labadie, B.; Heirz, T.; Mei, S.; Hasan, R.; Shafran, J.; Kelley, A.; Apostolov, E.; Al-Eryani, G.; Harvey, K.; Rameshbabu, S.; Loyd, M.; Bynoe, K.; Drovetsky, C.; Solanki, A.; Markiewicz, E.; Zamora, M.; Fan, X.; Schuerer, S.; Swarbrick, A.; Sykes, D.; Patnaik, A.
10.1101/2022.05.12.490223 — cancer biology — Posted on 2022-05-13
2483 ABL1 Kinase plays an important role in spontaneous and chemotherapy-induced genomic instability in multiple myeloma
KUMAR, S.; Talluri, S.; Zhao, J.; Liao, C.; Potluri, L. B.; Buon, L.; Mu, S.; Shi, J.; Chakraborty, C.; Tai, Y.-T.; Samur, M. K.; Shammas, M. A.; MUNSHI, N. C.
10.1101/2022.05.12.491727 — cancer biology — Posted on 2022-05-13
2491 In situ architecture and membrane fusion of SARS-CoV-2 Delta variant
Song, Y.; Yao, H.; Wu, N.; Zhang, Z.; Xu, J.; Peng, C.; Li, S.; Kong, W.; Chen, Y.; Zhu, M.; Wang, J.; Shi, D.; Zhao, C.; Lu, X.; Echavarria Galindo, M.; Li, S.
10.1101/2022.05.13.491759 — biophysics — Posted on 2022-05-13
2496 SPACE-GM: geometric deep learning of disease-associated microenvironments from multiplex spatial protein profiles.
Wu, Z.; Trevino, A. E.; Wu, E.; Swanson, K.; Kim, H. J.; D'Angio, H. B.; Preska, R.; Charville, G. W.; Dalerba, P. D.; Egloff, A. M.; Uppaluri, R.; Duvvuri, U.; Mayer, A. T.; Zou, J.
10.1101/2022.05.12.491707 — bioinformatics — Posted on 2022-05-13
2497 Tracking single cell evolution via clock-like chromatin accessibility
Wang, X.; Jin, W.; Wang, G.; Ju, L.; Chen, F.; Qian, K.; Xiao, Y.; Zhang, Y.
10.1101/2022.05.12.491736 — bioinformatics — Posted on 2022-05-13
2502 DirectMS1Quant: ultrafast quantitative proteomics with MS/MS-free mass spectrometry
Ivanov, M. V.; Bubis, J. A.; Gorshkov, V.; Tarasova, I. A.; Levitsky, L. I.; Solovyeva, E. M.; Lipatova, A. V.; Kjeldsen, F.; Gorshkov, M. V.
10.1101/2022.05.13.489895 — bioinformatics — Posted on 2022-05-13
2504 Antisense pairing and SNORD13 structure guide RNA cytidine acetylation
Thalalla Gamage, S.; Bortolin-Cavaille, M.-L.; Link, C. N.; Bryson, K. M.; Sas-Chen, A.; Schwartz, S.; Cavaille, J.; Meier, J. L.
10.1101/2022.05.12.491732 — biochemistry — Posted on 2022-05-13
2507 Translational Activity Controls Ribophagic Flux and Turnover of Distinct Ribosome Pools
Trendel, J.; Aleksic, M.; Bertolini, M.; Jochem, M.; Kramer, G.; Pfeffer, S.; Bukau, B.; Krijgsveld, J.
10.1101/2022.05.13.491786 — biochemistry — Posted on 2022-05-13
2508 Mouse primary T cell phosphotyrosine proteomics enabled by BOOST
Chua, X. Y.; Callahan, K. P.; Griffith, A. A.; Hildebrandt, T.; Fu, G.; Hu, M.; Wen, R.; Salomon, A.
10.1101/2022.05.13.491817 — biochemistry — Posted on 2022-05-13
2514 Climatic niche evolution of infectious diseases driving amphibian declines
Ellepola, G.; Herath, J.; Sun, D.; Pie, M. R.; Murray, K. A.; Pethiyagoda, R.; Hanken, J.; Meegaskumbura, M.
10.1101/2022.05.13.491758 — evolutionary biology — Posted on 2022-05-13
2515 The limits to ecological limits to diversification
Etienne, R. S.; Haegeman, B.; Dugo-Cota, A.; Vila, C.; Gonzalez-Voyer, A.; Valente, L.
10.1101/2022.05.13.491338 — evolutionary biology — Posted on 2022-05-13
2517 Systemic pesticides in a solitary bee pollen food store affect larval development and increase pupal mortality
Phan, N. T.; Joshi, N. K.; Rajotte, E. G.; Zhu, F.; Peter, K. A.; Lopez-Uribe, M. M.; Biddinger, D. J.
10.1101/2022.05.12.491686 — ecology — Posted on 2022-05-13
2520 The wild life of ticks: using passive surveillance to determine the distribution and wildlife host range of ticks and the exotic Haemaphysalis longicornis, 2010-2021
Thompson, A.; White, S.; Doub, E.; Sharma, P.; Frierson, K.; Dominguez, K.; Shaw, D.; Weaver, D.; Vigil, S.; Ruder, M.; Yabsley, M.
10.1101/2022.05.12.491673 — ecology — Posted on 2022-05-13
2521 Simulating alternative forest management in a changing climate on a Pinus nigra subsp. laricio plantation in Southern Italy
Testolin, R.; Dalmonech, D.; Marano, G.; Bagnara, M.; D'Andrea, E.; Matteucci, G.; Noce, S.; Collalti, A.
10.1101/2022.05.12.491636 — ecology — Posted on 2022-05-13
2522 Heme-deficient metabolism and impaired cellular differentiation as an evolutionary trade-off for human infectivity in Trypanosoma brucei gambiense
Horakova, E.; Lecordier, L.; Cunha, P.; Sobotka, R.; Changmai, P.; Langedijk, C. J. M.; Van Den Abbeele, J.; Vanhollebeke, B.; Luke, J.
10.1101/2022.05.12.491725 — developmental biology — Posted on 2022-05-13
2526 Replication stress tolerance and management differs between naive and primed pluripotent cells
Kafer, G. R.; O'Connor, A.; Rogers, S.; Osteil, P.; Nelson, C. B.; Pickett, H. A.; Tam, P. P.; Cesare, A. J.
10.1101/2022.05.12.491744 — developmental biology — Posted on 2022-05-13
2530 Assessment of Human Renal Transporter Based Drug-Drug Interactions Using Proximal Tubule Kidney-Chip
Nookala, A. R.; Ronxhi, J.; Sliz, J.; Jeanty, S.; Manatakis, D. V.; Jadalannagari, S.; Hamilton, G.; Park, H.; He, Y.; Lavarias, M.; Luo, G.; Jang, K.; McKenzie, D.
10.1101/2022.05.12.491717 — cell biology — Posted on 2022-05-13
2533 Galectin-9 interacts with Vamp-3 to regulate cytokine secretion in dendritic cells
Santalla Mendez, R.; Rodgers Furones, A.; Classens, R.; Haverdil, M.; Canela Capdevila, M.; van Duffelen, A.; ter Beest, M.; Spruijt, C. G.; Vermeulen, M.; van Spriel, A. B.; Querol Cano, L.
10.1101/2022.05.13.491792 — cell biology — Posted on 2022-05-13
2536 Longitudinal comparison of the developing gut virome in infants and their mothers
Federman, S.; Santos, Y.; Haggerty, T.; Sotomayor-Gonzalez, A.; Servellita, V.; Ley, R. E.; Parsonnet, J.; Chiu, C. Y.
10.1101/2022.05.13.491764 — microbiology — Posted on 2022-05-13
2540 Neuro-immune Crosstalk in the Enteric Nervous System from Early Postnatal Development to Adulthood
Viola, M. F.; Chavero Pieres, M.; Modave, E.; Stakenborg, N.; Delfini, M.; Fabre, N.; Appeltans, I.; Martens, T.; Vandereyken, K.; Van Herck, J.; Petry, P.; Verheijden, S.; De Schepper, S.; Sifrim, A.; KIERDORF, K.; Prinz, M.; Vanden Berghe, P.; Voet, T.; Boeckxstaens, G.
10.1101/2022.05.12.491517 — immunology — Posted on 2022-05-13
2541 Profile of Mycobacterium tuberculosis-specific CD4 T cells at the site of disease and blood in pericardial tuberculosis
Du Bruyn, E.; Ruzive, S.; Howlett, P. J.; Jacobs, A. J.; Lindestam Arlehamn, C. S.; Sette, A.; Sher, A.; Mayer-Barber, K. D.; Barber, D.; Mayosi, B.; Ntsekhe, M.; Wilkinson, R. J.; Riou, C.
10.1101/2022.05.12.491749 — immunology — Posted on 2022-05-13
2544 Expression and subcellular localization of USH1C/harmonin in the human retina provide insights into pathomechanisms and therapy
Nagel-Wolfrum, K.; Fadl, B. R.; Becker, M. M.; Wunderlich, K. A.; Schaefer, J.; Sturm, D.; Fritze, J.; Guer, B.; Kaplan, L.; Andreani, T.; Goldmann, T.; Brooks, M.; Starostik, M. R.; Apel, M.; Fath, K. R.; Stingl, K.; Kohl, S.; DeAngelis, M. M.; Schloetzer-Schrehardt, U.; Kim, I. K.; Owen, L. A.; Vetter, J. M.; Pfeiffer, N.; Andrade-Navarro, M. A.; Grosche, A. A.; Swaroop, A.; Wolfrum, U.
10.1101/2021.08.27.457962 — molecular biology — Posted on 2022-05-13
2545 Metabolic competition between lipid metabolism and histone methylation regulates sexual differentiation in human malaria parasites.
Harris, C. T.; Tong, X.; Campelo Morillo, R.; Vanheer, L. N.; Marreiros, I. M.; Nahiyaan, N.; Zuzarte-Luis, V. A.; Deitsch, K. W.; Mota, M. M.; Rhee, K. Y.; Kafsack, B. F. C.
10.1101/2022.01.18.476397 — systems biology — Posted on 2022-05-13
2548 Increased gene dosage and mRNA expression from chromosomal duplications in C. elegans
Ragipani, B.; Albritton, S. E.; Morao, A. K.; Mesquita, D.; Kramer, M.; Ercan, S.
10.1101/2022.03.22.485368 — genomics — Posted on 2022-05-13
2550 Foxd1 dependent induction of temporal retinal character is required for visual function
Hernandez-Bejarano, M.; Gestri, G.; Monfries, C.; Tucker, L.; Dragomir, E. I.; Bianco, I. H.; Bovolenta, P.; Wilson, S. W.; Cavodeassi, F.
10.1101/2022.05.12.491645 — developmental biology — Posted on 2022-05-13
2551 Deep learning-based approach for the characterization and quantification of histopathology in mouse models of colitis
Kobayashi, S.; Shieh, J.; Ruiz de Sabando, A.; Kim, J.; Liu, Y.; Zee, S. Y.; Prasanna, P.; Bialkowska, A. B.; Saltz, J. H.; Yang, V. W.
10.1101/2022.05.12.491690 — immunology — Posted on 2022-05-13
2552 Micro topographical instruction of bacterial attachment, biofilm formation and in vivo host response
Romero, M.; Luckett, J.; Figueredo, G.; Carabelli, A.; Scurr, D.; Hook, A.; Dubern, J.-F.; Ison, E.; Xue, X.; da Silva, A. C.; Blackburn, C.; Carlier, A.; Vasilevich, A. S.; Sudarsanam, P.; Vermeulen, S.; Winkler, D. A.; Ghaemmaghami, A. M.; de Boer, J.; Williams, P.; Alexander, M. R.
10.1101/2020.10.10.328146 — bioengineering — Posted on 2022-05-13
2553 The altered entry pathway and antigenic distance of the SARS-CoV-2 Omicron variant map to separate domains of spike protein
Peacock, T. P.; Brown, J. C.; Zhou, J.; Thakur, N.; Sukhova, K.; Newman, J.; Kugathasan, R.; Yan, A. W. C.; Furnon, W.; De Lorenzo, G.; Cowton, V. M.; Reuss, D.; Moshe, M.; Platt, O. K.; Quantrill, J. L.; Kaforou, M.; Patel, A. H.; Palmarini, M.; Bailey, D.; Barclay, W. S.
10.1101/2021.12.31.474653 — microbiology — Posted on 2022-05-13
2554 Brain Injury Localization in Electromagnetic Imaging using Symmetric Crossing Lines Method
Zhu, G.; Bialkowski, A.; Crozier, S.; Guo, L.; Nguyen, P.; Stancombe, A.; Abbosh, A.
10.1101/2021.09.22.461428 — biophysics — Posted on 2022-05-13
2555 Delivery of Circular mRNA via Degradable Lipid Nanoparticles against SARS-COV-2 Delta Variant
Huang, K.; Li, N.; Li, Y.; Zhu, J.; Fan, Q.; Yang, J.; Gao, Y.; Liu, Y.; Hou, Q.; Gao, S.; Wei, K.; Deng, C.; Zuo, C.; Sun, Z.
10.1101/2022.05.12.491597 — immunology — Posted on 2022-05-13
2556 VistoSeg: processing utilities for high-resolution Visium/Visium-IF images for spatial transcriptomics data
Tippani, M.; Divecha, H. R.; Catallini, J. L.; Kwon, S. H.; Weber, L. M.; Spangler, A.; Jaffe, A. E.; Hicks, S. C.; Martinowich, K.; Collado-Torres, L.; Page, S. C.; Maynard, K. R.
10.1101/2021.08.04.452489 — bioinformatics — Posted on 2022-05-13
2557 Genome-wide selection inference at short tandem repeats
Huang, B.; Durvasula, A.; Mousavi, N.; Ziaei-Jam, H.; Maksimov, M.; Lohmueller, K. E.; Gymrek, M.
10.1101/2022.05.12.491726 — genomics — Posted on 2022-05-13
2558 Tissue and cell-type specific molecular and functional signatures of 16p11.2 reciprocal genomic disorder across mouse brain and human neuronal models
Tai, D.; Razaz, P.; Erdin, S.; Gao, D.; Wang, J.; Nuttle, X.; de Esch, C. E.; Collins, R. L.; Currall, B. B.; O'Keefe, K.; Burt, N. D.; Yadav, R.; Wang, L.; Mohajeri, K.; Aneichyk, T.; Ragavendran, A.; Stortchevoi, A.; Morini, E.; Ma, W.; Lucente, D.; Hastie, A.; Kelleher, R. J.; Perlis, R. H.; Talkowski, M. E.; Gusella, J. F.
10.1101/2022.05.12.491670 — genomics — Posted on 2022-05-13
2560 Botrytis cinerea identifies host plants via the recognition of antifungal capsidiol to induce expression of a specific detoxification gene
Kuroyanagi, T.; Bulasag, A.; Fukushima, K.; Suzuki, T.; Tanaka, A.; Camagna, M.; Sato, I.; Chiba, S.; Ojika, M.; Takemoto, D.
10.1101/2022.05.11.490027 — microbiology — Posted on 2022-05-13
2561 Cytotoxic CD4+ T cells driven by T-cell intrinsic IL-18R/MyD88 signaling predominantly infiltrate Trypanosoma cruzi-infected hearts
Barbosa, C.-H. D.; Canto, F. B.; Gomes, A.; Brandao, L. M.; Lima, J. R.; Melo, G. A.; Granato, A.; Neves, E. G.; Oliveira, A.-C.; Dutra, W. O.; Nobrega, A.; Bellio, M.
10.1101/2021.10.21.465260 — immunology — Posted on 2022-05-13
2565 The length of the thalamo-cortical white matter fibers brings insight into sex differences in sleep spindle frequency
Gaudreault, P.-O.; JM Lina, j.-m.; Descoteaux, M.; Gosselin, N.; Doyon, J.; Deslauriers-Gauthier, S.; Carrier, J.
10.1101/2022.05.11.491489 — neuroscience — Posted on 2022-05-13
2567 Increased sensorimotor structural connectivity in high schizotypy
Messaritaki, E.; Foley, S.; Barawi, K.; Ettinger, U.; Jones, D. K.
10.1101/2022.05.12.491533 — neuroscience — Posted on 2022-05-13
2572 Foxd1 dependent induction of temporal retinal character is required for visual function
Hernandez-Bejarano, M.; Gestri, G.; Monfries, C.; Tucker, L.; Dragomir, E. I.; Bianco, I. H.; Bovolenta, P.; Wilson, S. W.; Cavodeassi, F.
10.1101/2022.05.12.491645 — developmental biology — Posted on 2022-05-13
2573 Deep learning-based approach for the characterization and quantification of histopathology in mouse models of colitis
Kobayashi, S.; Shieh, J.; Ruiz de Sabando, A.; Kim, J.; Liu, Y.; Zee, S. Y.; Prasanna, P.; Bialkowska, A. B.; Saltz, J. H.; Yang, V. W.
10.1101/2022.05.12.491690 — immunology — Posted on 2022-05-12
2577 Evaluating Stored Platelet Shape Change Using Imaging Flow Cytometry
Yakovenko, O.; Ozpolat, T.; Stratiievska, A.; Bailey, S. L.; Miles, J.; Usaneerungrueng, C.; Wu, X.; Stolla, M.
10.1101/2022.05.12.491681 — pathology — Posted on 2022-05-12
2578 Structure and mechanism of LARGE1 matriglycan polymerase
Joseph, S.; Schnicker, N. J.; Xu, Z.; Yang, T.; Hopkins, J.; Watkins, M.; Chakravarthy, S.; Davulcu, O.; Anderson, M. E.; Venzke, D.; Campbell, K. P.
10.1101/2022.05.12.491222 — biochemistry — Posted on 2022-05-12
2579 Stromal Hippo-YAP signaling in stem cell niche controls intestinal homeostasis
Mao, J.; Dang, K.; Singh, A.; Jennifer, C. L.; Tao, Z.; Liu, H.; Zhu, L.; Wu, X.
10.1101/2022.05.12.491640 — developmental biology — Posted on 2022-05-12
2581 Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families
Wilson, B.; Gemperle, J.; Lawless, C.; Flett, C.; Hartshorn, M.; Hinde, E.; Harrison, T.; Chastney, M.; Taylor, S.; Allen, J.; Caswell, P. T.
10.1101/2022.05.12.491689 — cell biology — Posted on 2022-05-12
2582 Induced pluripotent stem cells and cerebral organoids from the critically endangered Sumatran rhinoceros
Zywitza, V.; Frahm, S.; Krueger, N.; Weise, A.; Goeritz, F.; Hermes, R.; Holtze, S.; Colleoni, S.; Galli, C.; Drukker, M.; Hildebrandt, T. B.; Diecke, S.
10.1101/2022.05.12.491654 — cell biology — Posted on 2022-05-12
2583 Drosophila melanogaster is a powerful host model to study mycobacterial virulence
Fuentes, E.; Sivakumar, N.; Selvik, L.-K.; Arch, M.; Cardona, P. J.; Ioerger, T. R.; Dragset, M. S.
10.1101/2022.05.12.491628 — microbiology — Posted on 2022-05-12
2584 Insulin-like Growth Factor-1 Synergizes with IL-2 to Induce Homeostatic Proliferation of Regulatory T cells
Shapiro, M. R.; Peters, L. D.; Brown, M. E.; Cabello-Kindelan, C.; Posgai, A. L.; Bayer, A. L.; Brusko, T. M.
10.1101/2022.05.12.491665 — immunology — Posted on 2022-05-12
2585 Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72-ALS iPSC-derived microglia contributes to neurodegeneration
Banerjee, P.; Mehta, A. R.; Nirujogi, R. S.; Cooper, J.; James, O. G.; Nanda, J.; Longden, J.; Salzinger, A.; Paza, E.; Newton, J.; Story, D.; Pal, S.; Smith, C.; Alessi, D. R.; Selvaraj, B. T.; Priller, J.; Chandran, S.
10.1101/2022.05.12.491675 — neuroscience — Posted on 2022-05-12
2587 RNA Methylome Reveals the m6A-Mediated Regulation of Flavor Metabolites in Tea Leaves under Solar-Withering
Zhu, C.; Zhang, S.; Zhou, C.; Tian, C.; Shi, B.; Xu, K.; Huang, L.; Sun, Y.; Lin, Y.; Lai, Z.; Guo, Y.
10.1101/2022.05.12.491608 — plant biology — Posted on 2022-05-12
2589 Structural basis underlying specific biochemical activities of non-muscle tropomyosin isoforms
Selvaraj, M.; Kokate, S.; Reggiano, G.; Kogan, K.; Kotila, T.; Kremneva, E.; DiMaio, F.; Lappalainen, P.; Huiskonen, J. T.
10.1101/2022.05.12.491677 — biochemistry — Posted on 2022-05-12
2591 Evaluation of metagenomic, 16S rRNA gene and ultra-plexed PCR-based sequencing approaches for profiling antimicrobial resistance gene and bacterial taxonomic composition of polymicrobial samples
Chau, K.; Matlock, W.; Constantinides, B.; Lipworth, S.; Newbold, L.; Tipper, H.; Goodall, T.; Brett, H.; Hughes, J.; Crook, D. W.; Eyre, D. W.; Read, D.; Walker, A. S.; Stoesser, N.
10.1101/2022.05.12.491637 — genomics — Posted on 2022-05-12
2595 Myofiber reconstruction at micron scale reveals longitudinal bands in heart ventricular walls
Dileep, D.; Syed, T. A.; Sloan, T. F. W.; Perundurai, D.; Siddiqi, K.; Sirajuddin, M.
10.1101/2022.05.12.491149 — cell biology — Posted on 2022-05-12
2598 Mapping the risk of Rift Valley fever in Uganda using national seroprevalence data from cattle, sheep and goats
Tumusiime, D.; Isingoma, E.; Tashoroora, O. B.; Ndumu, D. B.; Bahati, M.; Nantima, N.; Mugizi, D. R.; Jost, C.; Bett, B.
10.1101/2022.05.12.491594 — microbiology — Posted on 2022-05-12
2599 Small-molecule inhibitors targeting prokaryotic ClpQ protease in Plasmodium display anti-malarial efficacies against blood and liver stages
Jain, S.; Asad, M.; Caldelari, R.; Datta, G.; Singh, S.; Rathore, S.; Stanway, R. R.; Heussler, V. T.; Mohmmed, A.
10.1101/2022.05.12.491652 — microbiology — Posted on 2022-05-12
2602 Proliferation is a driver of quorum sensing in an in vitro model of tissue resident macrophages
Rajab, N.; Gearing, L. J.; Prawer, Y. D. J.; Angel, P. W.; Grimmond, S. M.; Laslett, A. L.; Choi, J.; Wells, C.
10.1101/2022.05.12.491598 — systems biology — Posted on 2022-05-12
2603 Characterization of full-length CNBP expanded alleles in myotonic dystrophy type 2 patients by Cas9-mediated enrichment and nanopore sequencing
Alfano, M.; De Antoni, L.; Centofanti, F.; Visconti, V. V.; Maestri, S.; Degli Esposti, C.; Massa, R.; D'Apice, M. R.; Novelli, G.; Delledonne, M.; Botta, A.; Rossato, M.
10.1101/2022.05.12.491603 — genomics — Posted on 2022-05-12
2604 A human and rhesus macaque interferon-stimulated gene screen reveals ARHGEF3/XPLN as an antiviral gene against hepatitis C virus and other flaviviruses
Bamford, C.; Aranday-Cortes, E.; Sanchez-Velazquez, R.; Mullan, C.; Kohl, A.; Patel, A. H.; Wilson, S. J.; McLauchlan, J.
10.1101/2022.05.12.491650 — microbiology — Posted on 2022-05-12
2608 Structural biases in disordered proteins are prevalent in the cell
Moses, D.; Guadalupe, K.; Yu, F.; Flores, E.; Perez, A.; McAnelly, R. L.; Shamoon, N. M.; Cuevas-Zepeda, E.; Merg, A.; Martin, E. W.; Holehouse, A. S.; Sukenik, S.
10.1101/2021.11.24.469609 — biophysics — Posted on 2022-05-12
2611 Patterns of Structural Variation Define Prostate Cancer Across Disease States
Zhou, M.; Ko, M.; Hoge, A. C.; Luu, K.; Liu, Y.; Russell, M. L.; Hannon, W. W.; Zhang, Z.; Carrot-Zhang, J.; Beroukhim, R.; Van Allen, E.; Choudhury, A. D.; Nelson, P. S.; Freedman, M. L.; Taplin, M.-E.; Meyerson, M.; Viswanathan, S. R.; Ha, G.
10.1101/2022.01.09.475586 — genomics — Posted on 2022-05-12
2613 CDK9 and PP2A regulate RNA polymerase II transcription termination and coupled RNA maturation.
Tellier, M.; Zaborowska, J.; Neve, J.; Nojima, T.; Hester, S.; Fournier, M.; Furger, A.; Murphy, S.
10.1101/2021.06.21.449289 — molecular biology — Posted on 2022-05-12
2614 GlycoVHH: Introducing N-glycans on the camelid VHH antibody scaffold - Optimal sites and use for macrophage delivery
van Schie, L.; Van Breedam, W.; Roels, C.; Schepens, B.; Frank, M.; Mehdipour, A. R.; Laukens, B.; Nerinckx, W.; Santens, F.; Devos, S.; Rossey, I.; Thooft, K.; Vanmarcke, S.; Van Hecke, A.; Callewaert, N.
10.1101/2022.04.25.489312 — molecular biology — Posted on 2022-05-12
2615 Clinical and molecular correlates of CD39+ CD8 T cells in patients with lung cancer
Chow, A.; Uddin, F. Z.; Mangarin, L.; Rizvi, H.; Dobrin, A.; Tischfield, S. E.; Quintanal-Villalonga, A.; Chan, J. M.; Shah, N. S.; Allaj, V.; Manoj, P.; Mattar, M.; Meneses, M.; Liu, M.; Landau, R.; Ward, M.; Kulick, A.; Kwong, C.; Wierzbicki, M.; Yavner, J.; Chavan, S.; Farillas, A.; Holland, A.; Sridhar, H.; Ciampricotti, M.; Hirschhorn-Cymerman, D.; Richards, A.; Donoghue, M. T. A.; Heller, G.; Klebanoff, C. A.; Hellmann, M. D.; de Stanchina, E.; Sen, T.; Wolchok, J. D.; Merghoub, T.; Rudin, C. M.
10.1101/2022.01.24.477554 — immunology — Posted on 2022-05-12
2617 A New Paradigm for Investigating Real-World Social Behavior and its Neural Underpinnings
Alreja, A.; Ward, M. J.; Ma, Q.; Russ, B. E.; Bickel, S.; Van Wouwe, N. C.; Gonzalez-Martinez, J. A.; Neimat, J. S.; Abel, T. J.; Bagic, A.; Parker, L. S.; Richardson, R. M.; Schroeder, C. E.; Morency, L.-P.; Ghuman, A. S.
10.1101/2021.12.26.474173 — neuroscience — Posted on 2022-05-12
2619 Reproducibility of in-vivo electrophysiological measurements in mice
The International Brain Laboratory, ; Banga, K.; Benson, J.; Bonacchi, N.; Bruijns, S. A.; Campbell, R.; Chapuis, G. A.; Churchland, A. K.; Davatolhagh, M. F.; Lee, H. D.; Faulkner, M.; Hu, F.; Hunterberg, J.; Khanal, A.; Krasniak, C.; Meijer, G. T.; Miska, N. J.; Mohammadi, Z.; Noel, J.-P.; Paninski, L.; Pan-Vazquez, A.; Roth, N.; Schartner, M.; Socha, K.; Steinmetz, N. A.; Svoboda, K.; Taheri, M.; Urai, A. E.; Wells, M.; West, S. J.; Whiteway, M. R.; Winter, O.; Witten, I. B.
10.1101/2022.05.09.491042 — neuroscience — Posted on 2022-05-12
2620 Robust cone-mediated signaling persists late into rod photoreceptor degeneration
Scalabrino, M. L.; Thapa, M.; Chew, L. A.; Zhang, E.; Xu, J. Q.; Sampath, A.; Chen, J.; Field, G. D.
10.1101/2022.04.27.489758 — neuroscience — Posted on 2022-05-12
2621 A novel triple-action inhibitor targeting B-cell receptor signaling and BRD4 demonstrates preclinical activity in chronic lymphocytic leukemia
Smith, A. L.; Eiken, A. P.; Moore, D. Y.; Umeta, L. T.; Smith, L. M.; Lyden, E. R.; D'Angelo, C. R.; Kallam, A.; Vose, J. M.; Kutateladze, T. G.; El-Gamal, D.
10.1101/2022.05.11.491547 — cancer biology — Posted on 2022-05-12
2622 Reference-based cell type matching of spatial transcriptomics data
Zhang, Y.; Miller, J. A.; Park, J.; Lelieveldt, B. P.; Long, B.; Abdelaal, T.; Aevermann, B. D.; Biancalani, T.; Comiter, C.; Dzyubachyk, O.; Mattsson Langseth, C.; Petukhov, V.; Scalia, G.; Vaishnav, E. D.; Zhao, Y.; Lein, E. S.; Scheuermann, R. H.
10.1101/2022.03.28.486139 — bioinformatics — Posted on 2022-05-12
2626 Delivery of Circular mRNA via Degradable Lipid Nanoparticles against SARS-COV-2 Delta Variant
Huang, K.; Li, N.; Li, Y.; Zhu, J.; Fan, Q.; Yang, J.; Gao, Y.; Liu, Y.; Hou, Q.; Gao, S.; Wei, K.; Deng, C.; Zuo, C.; Sun, Z.
10.1101/2022.05.12.491597 — immunology — Posted on 2022-05-12
2629 The SARS-CoV-2 Spike Protein Activates the Epidermal Growth Factor Receptor-Mediated Signaling
Palakkott, A.; Alneyadi, A.; Muhammad, K.; Ali, E. H.; Amiri, K.; Ayoub, M. A.; Iratni, R.
10.1101/2022.05.10.491351 — cell biology — Posted on 2022-05-12
2630 Biochemical Characterization of Emerging SARS-CoV-2 Nsp15 Endoribonuclease Variants
Wilson, I. M.; Frazier, M. N.; Li, J.-L. N.; Randall, T. A.; Stanley, R. E.
10.1101/2022.05.10.491349 — microbiology — Posted on 2022-05-12
2632 A Mathematical Model of the Within-Host Kinetics of SARS-CoV-2 Neutralizing Antibodies Following COVID-19 Vaccination
dePillis, L.; Caffrey, R.; Chen, G.; Dela, M. D.; Eldevik, L.; McConnell, J.; Shabahang, S.; Varvel, S. A.
10.1101/2022.05.11.491557 — immunology — Posted on 2022-05-12
2635 Contrasting patterns of genetic admixture explain the phylogeographic history of Iberian high mountain populations of midwife toads
Lucati, F.; Miro, A.; Bosch, J.; Caner, J.; Jowers, M. J.; Rivera, X.; Donaire-Barroso, D.; Rebelo, R.; Ventura, M.
10.1101/2022.05.12.490531 — genetics — Posted on 2022-05-12
2643 Phototherapy with physically and molecularly produced light for Alzheimer's disease
Kuang, S.; Zhu, B.; Zhang, J.; Yang, F.; Wu, B.; Ding, W.; Sheng, S.; Zhang, C.; Ran, C.
10.1101/2022.02.10.478818 — biochemistry — Posted on 2022-05-12
2646 Small molecule-mediated insulin hypersecretion induces transient unfolded protein response and loss of beta cell function
Rodrigues dos Santos, K.; Roy, G.; Binns, D. D.; Grzemska, M. G.; Barella, L. F.; Armoo, F.; McCoy, M. K.; Huynh, A. V.; Yang, J. Z.; Posner, B. A.; Cobb, M. H.; Kalwat, M. A.
10.1101/2022.03.07.482881 — cell biology — Posted on 2022-05-12
2649 IL-13-programmed airway tuft cells produce PGE2, which promotes CFTR-dependent mucociliary function
Kotas, M. E.; Moore, C. M.; Gurrola, J. G.; Pletcher, S. D.; Goldberg, A. N.; Alvarez, R.; Yamato, S.; Bratcher, P. E.; Shaughnessy, C. A.; Zeitlin, P. L.; Zhang, I.; Li, Y.; Montgomery, M. T.; Lee, K.; Cope, E. K.; Locksley, R. M.; Seibold, M. A.; Gordon, E. D.
10.1101/2022.05.11.491556 — immunology — Posted on 2022-05-12
2654 Optogenetic rejuvenation of mitochondrial membrane potential extends C. elegans lifespan
Berry, B. J.; Vodickov, A.; Mueller-Eigner, A.; Meng, C.; Ludwig, C.; Kaeberlein, M.; Peleg, S.; Wojtovich, A. P.
10.1101/2022.05.11.491574 — physiology — Posted on 2022-05-12
2655 Proteogenomic characterization of age and sex interactions in cardiac gene expression
Han, Y.; Wennersten, S. A.; Wright, J.; Ludwig, R. W.; Lau, E.; Lam, M. P. Y.
10.1101/2022.05.11.491401 — physiology — Posted on 2022-05-12
2662 Fermented foods restructure gut microbiota and promote immune regulation via microbial metabolites
Spencer, S. P.; Lemus Silva, E. G.; Caffrey, E.; Culver, R. N.; Gellman, R. H.; Wang, M.; Wastyk, H.; Higginbottom, S.; Sonnenburg, J. L.
10.1101/2022.05.11.490523 — microbiology — Posted on 2022-05-12
2664 B cell receptor stimulation induces IgE plasma cell apoptosis
Wade-Vallance, A. K.; Yang, Z.; Libang, J. B.; Robinson, M. J.; Tarlinton, D. M.; Allen, C. D. C.
10.1101/2022.05.11.491510 — immunology — Posted on 2022-05-12
2665 Genome-wide analysis of dendritic cell differentiation
Tiniakou, I.; Hsu, P.-F.; Lopez-Zepeda, L. S.; Lau, C. M.; Soni, C.; Esteva, E.; Adams, N.; Liu, F.; Khodadadi-Jamayran, A.; Rodrick, T.; Jones, D.; Tsirigos, A.; Ohler, U.; Bedford, M. T.; Nimer, S. D.; Reizis, B.
10.1101/2022.05.11.491577 — immunology — Posted on 2022-05-12
2668 A label-free method to track individuals and lineages of budding cells
Pietsch, J. M. J.; Munoz, A. F.; Adjavon, D.-Y. A.; Farquhar, I.; Clark, I. B.; Swain, P. S.
10.1101/2022.05.11.491488 — systems biology — Posted on 2022-05-12
2669 Parasites, infections and inoculation in synthetic minimal cells
Cash, B.; Gaut, N. J.; Deich, C.; Johnson, L. L.; Engelhart, A. E.; Adamala, K. P.
10.1101/2022.05.11.491559 — synthetic biology — Posted on 2022-05-12
2670 High throughput peptidomics elucidates immunoregulatory functions of plant thimet oligopeptidase-directed proteostasis
Popescu, G. V.; Popescu, S. C.; Hicks, L. M.; Wommack, A. J.; Iannetta, A. A.; Berg, P.; Nejat, N.; Smythers, A. L.; Setu, R.; Wesser, U.; Purvis, A. L.; Brown, Z. A.
10.1101/2022.05.11.491536 — plant biology — Posted on 2022-05-12
2671 RFcaller: a machine learning approach combined with read-level features to detect somatic mutations
Diaz-Navarro, A.; Bousquets-Munoz, P.; Nadeu, F.; Lopez-Tamargo, S.; Bea, S.; Campo, E.; Puente, X. S.
10.1101/2022.05.11.491496 — cancer biology — Posted on 2022-05-12
2675 Strategic exploration in the macaque prefrontal cortex
Jahn, C. I.; Grohn, J.; Cuell, S.; Emberton, A.; Bouret, S.; Walton, M. E.; Kolling, N.; Sallet, J.
10.1101/2022.05.11.491468 — neuroscience — Posted on 2022-05-12
2678 HumanMine: advanced data searching, analysis and cross-species comparison.
Lyne, R.; Bazaga, A.; Butano, D.; Contrino, S.; Heimbach, J.; Hu, F.; Kalderimis, A.; Lyne, M.; Reierskog, K.; Stepan, R.; Sullivan, J.; Wise, A.; Yehudi, Y.; Micklem, G.
10.1101/2022.05.11.491545 — genomics — Posted on 2022-05-12
2679 Visinity: Visual Spatial Neighborhood Analysis for Multiplexed Tissue Imaging Data
Warchol, S.; Krueger, R.; Nirmal, A. J.; Gaglia, G.; Jessup, J.; Ritch, C. C.; Hoffer, J.; Muhlich, J. L.; Burger, M.; Jacks, T. L.; Santagata, S.; Sorger, P. K.; Pfister, H.
10.1101/2022.05.09.490039 — cell biology — Posted on 2022-05-12
2680 A Scalable Screening of E. coli Strains for Recombinant Protein Expression
Morao, L. G.; Manzine, L. R.; Clementino, L. O. D.; Wrenger, C.; Nascimento, A. S.
10.1101/2021.03.09.434560 — molecular biology — Posted on 2022-05-12
2681 Eudicot primary cell wall glucomannan is related in synthesis, structure and function to xyloglucan
Yu, L.; Yoshimi, Y.; Cresswell, R.; Wightman, R.; Lyczakowski, J. J.; Wilson, L. F. L.; Ishida, K.; Stott, K.; Yu, X.; Charalambous, S.; Wurman-Rodrich, J.; Dupree, R.; Terrett, O. M.; Brown, S.; Temple, H.; Krogh, K. B. R. M.; Dupree, P.
10.1101/2022.05.11.491508 — plant biology — Posted on 2022-05-12
2682 RAS and PP2A activities converge on epigenetic gene regulation
Aakula, A.; Sharma, M.; Tabaro, F.; Honkanen, H.; Schapira, M.; Arrowsmith, C.; Nykter, M.; Westermarck, J.
10.1101/2022.05.11.491459 — cancer biology — Posted on 2022-05-12
2683 Gamete interaction protein evolution evinces Pantherines hybridizing history
Pisciottano, F.; Campos, M. C.; Penna, C.; Bruque, C. D.; Gabaldon, T.; Saragueta, P.
10.1101/2022.03.22.485370 — evolutionary biology — Posted on 2022-05-12
2684 Accelerating the clock: Interconnected speedup of energetic and molecular dynamics during aging in cultured human cells
Sturm, G.; Bobba-Alves, N.; Tumasian, R. A.; Michelson, J.; Ferrucci, L.; Kempes, C. P.; Picard, M.
10.1101/2022.05.10.491392 — cell biology — Posted on 2022-05-12
2685 Tau seeds translocate across the cell membrane to initiate aggregation
Dodd, D. A.; LaCroix, M. S.; Valdez, C.; Knox, G. M.; Vega, A. R.; Kumar, A.; Xing, C.; White, C. L.; Diamond, M. I.
10.1101/2022.05.10.491429 — cell biology — Posted on 2022-05-12
2689 Thermal endurance by a hot-spring-dwelling phylogenetic relative of the mesophilic Paracoccus
Mondal, N.; Roy, C.; Chatterjee, S.; Sarkar, J.; Dutta, S.; Bhattacharya, S.; Chakraborty, R.; Ghosh, W.
10.1101/2022.05.08.491110 — microbiology — Posted on 2022-05-12
2691 Distributed harmonic patterns of structure-function dependence orchestrate human consciousness
Luppi, A. I.; Vohryzek, J.; Kringelbach, M. L.; Mediano, P. A. M.; Craig, M. M.; Adapa, R.; Carhart-Harris, R. L.; Roseman, L.; Pappas, I.; Peattie, A. R. D.; Manktelow, A. E.; Sahakian, B. J.; Finoia, P.; Williams, G. B.; Allanson, J.; Pickard, J. D.; Menon, D. K.; Atasoy, S.; Stamatakis, E. A.
10.1101/2020.08.10.244459 — neuroscience — Posted on 2022-05-12
2692 Heritability of hippocampal functional and microstructural organisation
Bayrak, S.; Vos de Wael, R.; Schaare, H. L.; Hettwer, M. D.; Caldairou, B.; Bernasconi, A.; Bernasconi, N.; Bernhardt, B. C.; Valk, S. L.
10.1101/2021.11.10.468049 — neuroscience — Posted on 2022-05-12
2693 Ubiquitin proteomics uncovers RNA polymerase I as a critical target of the Nse1 RING domain
Ibars, E.; Codina-Fabra, J.; Belli, G.; Casas, C.; Tarres, M.; Sole-Soler, R.; Lorite, N. p.; Ximenez-Embun, P.; Munoz, J.; Colomina, N.; Torres-Rosell, J.
10.1101/2021.12.11.472054 — molecular biology — Posted on 2022-05-12
2694 Microbial dysbiosis and metabolic disorders promote rheumatoid arthritis across successive stages: a multi-omics cohort study
Cheng, M.; Zhao, Y.; Cui, Y.; Zhong, C.; Zha, Y.; Li, S.; Cao, G.; Li, M.; Zhang, L.; Ning, K.; Han, J.
10.1101/2022.02.13.480248 — microbiology — Posted on 2022-05-12
2695 In vitro coinfection by influenza A virus and respiratory syncytial virus generates hybrid viral particles with altered structure and tropism
Haney, J.; Vijayakrishnan, S.; Streetley, J.; Dee, K.; Goldfarb, D.; Clarke, M.; Mullin, M.; Carter, S. D.; Bhella, D.; Murcia, P. R.
10.1101/2021.08.16.456460 — microbiology — Posted on 2022-05-12
2698 A Chitin-Binding Protein Ultra-highly expressed in the Outer Fold of Mantle is Related to Shell Colour in Pacific Oyster Crassostrea gigas
Li, M.; Tang, J.; Huang, B.; Liu, Y.; Wei, L.; Han, Y.; Wang, X.; Sang, X.; Yuan, M.; Fan, N.; Cai, S.; Zheng, Y.; Zhang, M.; Wang, X.
10.1101/2022.04.18.488701 — physiology — Posted on 2022-05-12
2700 Magnetic Enrichment of Immuno-Specific Extracellular Vesicles for Mass Spectrometry Using Biofilm-Derived Iron Oxide Nanowires
Pham, Q. N.; Winter, M.; Milanova, V.; Young, C.; Condina, M. R.; Hoffmann, P.; Pham, N. T. H.; Tung, T. T.; Losic, D.; Thierry, B.
10.1101/2022.05.01.490183 — bioengineering — Posted on 2022-05-11
2701 Botrytis cinerea identifies host plants via the recognition of antifungal capsidiol to induce expression of a specific detoxification gene
Kuroyanagi, T.; Bulasag, A.; Fukushima, K.; Suzuki, T.; Tanaka, A.; Camagna, M.; Sato, I.; Chiba, S.; Ojika, M.; Takemoto, D.
10.1101/2022.05.11.490027 — microbiology — Posted on 2022-05-11
2702 IL-21 has a critical role in establishing germinal centers by amplifying early B cell proliferation
Dvorscek, A. R.; McKenzie, C. I.; Robinson, M. J.; Ding, Z.; Pitt, C.; O'Donnell, K.; Zotos, D.; Brink, R.; Tarlinton, D. M.; Quast, I.
10.1101/2022.01.21.476732 — immunology — Posted on 2022-05-11
2703 FAMetA: a mass isotopologue-based tool for the comprehensive analysis of fatty acid metabolism
Alcoriza-Balaguer, M. I.; Garcia-Canaveras, J. C.; Benet, M.; Juan Vidal, O.; Lahoz, A.
10.1101/2022.05.11.491462 — systems biology — Posted on 2022-05-11
2705 Regulation of defective mitochondrial DNA accumulation and transmission in C. elegans by the programmed cell death and aging pathways
Flowers, S. E.; Kothari, R.; Torres Cleuren, Y. N.; Alcorn, M. R.; Ewe, C. K.; Alok, G.; Joshi, P. M.; Rothman, J. H.
10.1101/2021.10.27.466108 — genetics — Posted on 2022-05-11
2706 Proteomic Analysis of Huntington's Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets
Tshilenge, K.-T.; Galicia Aguirre, C.; Bons, J.; Basisty, N.; Song, S.; Rose, J.; Lopez-Ramirez, A.; Akos Gerencser, A.; Naphade, S.; Loureiro, A.; Wehrfritz, C.; Holtz, A.; Mooney, S.; Schilling, B.; Ellerby, L.
10.1101/2022.05.11.491152 — neuroscience — Posted on 2022-05-11
2712 A dynamic in vitro model of Down Syndrome neurogenesis with Trisomy 21 gene dosage correction
Bansal, P.; Banda, E. C.; Glatt-Deeley, H. R.; Stoddard, C.; Ahern, D. T.; Kondaveeti, Y.; Nicouleau, M.; Pinter, S. F.
10.1101/2022.05.11.491519 — developmental biology — Posted on 2022-05-11
2713 Three ALS genes regulate expression of the MHC class II antigen presentation pathway
Chi, B.; Ozturk, M. M.; Paraggio, C. L.; Leonard, C. E.; Sanita, M. E.; Dastpak, M.; O'Connell, J. D.; Coady, J. A.; Zhang, J.; Gygi, S. P.; Lopez-Gonzalez, R.; Reed, R.
10.1101/2022.05.11.489680 — molecular biology — Posted on 2022-05-11
2715 A phospho-switch provided by LRR receptor-like kinase, ALK1/QSK1/KIN7, prioritizes ABCG36/PEN3/PDR8 transport toward defense
Aryal, B.; Xia, J.; Hu, Z.; Tsering, T.; Liu, J.; Huynh, J.; Fukao, Y.; Gloeckner, N.; Huang, H. Y.; Sancho-Andres, G.; Pakula, K.; Gorzolka, K.; Zwiewka, M.; Nodzynski, T.; Harter, K.; Sanchez-Rodriguez, C.; Jasinski, M.; Rosahl, S.; Geisler, M. M.
10.1101/2022.05.11.491457 — plant biology — Posted on 2022-05-11
2716 Mitochondrial Pyruvate Carrier Inhibition Initiates Metabolic Crosstalk to Stimulate Branched Chain Amino Acid Catabolism
Ferguson, D.; Eichler, S. J.; Yiew, N. K. H.; Colca, J. R.; Cho, K.; Patti, G. J.; McCommis, K. S.; Niemi, N. M.; Finck, B.
10.1101/2022.05.11.491550 — physiology — Posted on 2022-05-11
2717 A novel triple-action inhibitor targeting B-cell receptor signaling and BRD4 demonstrates preclinical activity in chronic lymphocytic leukemia
Smith, A. L.; Eiken, A. P.; Moore, D. Y.; Umeta, L. T.; Smith, L. M.; Lyden, E. R.; D'Angelo, C. R.; Kallam, A.; Vose, J. M.; Kutateladze, T. G.; El-Gamal, D.
10.1101/2022.05.11.491547 — cancer biology — Posted on 2022-05-11
2718 Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA
Warren, G. D.; Kitao, T.; Franklin, T. G.; Nguyen, J. V.; Geurink, P. P.; Kubori, T.; Nagai, H.; Pruneda, J. N.
10.1101/2022.05.11.491541 — biochemistry — Posted on 2022-05-11
2719 Extensive single-cell genomics reveals bacterial diversity and diverse phage host ranges in the area in and around the Red Sea
Nishikawa, Y.; Kogawa, M.; Hosokawa, M.; Wagatsuma, R.; Mineta, K.; Takahashi, K.; Ide, K.; Yura, K.; Behzad, H.; Gojobori, T.; Takeyama, H.
10.1101/2020.03.05.962001 — genomics — Posted on 2022-05-11
2720 Reconstruction and deconstruction of human somitogenesis in vitro
Miao, Y.; Djeffal, Y.; De Simone, A.; Zhu, K.; Silberfeld, A.; Lee, J. G.; Rao, J.; Tarazona, O. A.; Mongera, A.; Rigoni, P.; Diaz-Cuadros, M.; Song, L. M. S.; Di Talia, S.; Pourquie, O.
10.1101/2022.05.11.491561 — developmental biology — Posted on 2022-05-11
2722 APOE Expression and Secretion are Modulated by Copper-Dependent and -Independent Mitochondrial Dysfunction
Wynne, M. E.; Ogunbona, O.; Lane, A. R.; Gokhale, A.; Zlatic, S. A.; Xu, C.; Wen, Z.; Duong, D.; Ivanova, A.; Orlund, E. A.; Seyfried, N. T.; Crocker, A.; Shanbhag, V.; Petris, M.; Senoo, N.; Kandasamy, S.; Claypool, S. M.; Wingo, A. P.; Wingo, T. S.; Levey, A.; Werner, E.; Faundez, V.
10.1101/2022.05.11.491499 — cell biology — Posted on 2022-05-11
2723 DNA double strand breaks lead to de novo transcription and translation of damage-induced long RNAs in planta
Schreiber, T.; Tripathee, S.; Iwen, T.; Prange, A.; Vahabi, K.; Gruetzner, R.; Horn, C.; Marillonnet, S.; Tissier, A. F.
10.1101/2022.05.11.491484 — molecular biology — Posted on 2022-05-11
2726 Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells
Jin, H.; Ladd, N. A.; Peev, A. M.; Swarbrick, G. M.; Cansler, M.; Null, M.; Boughter, C. T.; McMurtrey, C.; Nilsen, A.; Dobos, K. M.; Hildebrand, W. H.; Lewinsohn, D. A.; Adams, E. J.; Lewinsohn, D. M.; Harriff, M.
10.1101/2022.05.11.491531 — immunology — Posted on 2022-05-11
2727 Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases
Nutma, E.; Fancy, N.; Weinert, M.; Marzin, M. C.; Tsartsalis, S.; Muirhead, R. C.; Falk, I.; de Bruin, J.; Hollaus, D.; Pieterman, R.; Anink, J.; Story, D.; Chandran, S.; Tang, J.; Trolese, M. C.; Saito, T.; Saido, T. C.; Wiltshire, K.; Beltran-Lobo, P.; Philips, A.; Antel, J.; Healy, L.; Moore, C. S.; Bendotti, C.; Aronica, E.; Radulescu, C. I.; Barnes, S. J.; Hampton, D. W.; van der Valk, P.; Jacobson, S.; Matthews, P. M.; Amor, S.; Owen, D. R.
10.1101/2022.05.11.491453 — neuroscience — Posted on 2022-05-11
2730 Membrane-associated shortened Trk receptors promote neuroprotection and robust axon regeneration without ligands
Nishijima, E.; Honda, S.; Kitamura, Y.; Namekata, K.; Kimura, A.; Guo, X.; Azuchi, Y.; Harada, C.; Murakami, A.; Matsuda, A.; Nakano, T.; Parada, L.; Harada, T.
10.1101/2022.05.11.491487 — neuroscience — Posted on 2022-05-11
2733 Characterization and visualization of global metabolomic responses of Brachypodium distachyon to environmental changes
Mahood, E. H.; Bennett, A. A.; Komatsu, K.; Kruse, L. H.; Lau, V.; Ishka, M. R.; Jiang, Y.; Bravo, A.; Bowen, B. P.; Louie, K.; Harrison, M. J.; Provart, N. J.; Vatamaniuk, O. K.; Moghe, G. D.
10.1101/2022.05.11.491395 — plant biology — Posted on 2022-05-11
2735 Screening of hydrocarbon-stapled peptides for inhibition of calcium-triggered exocytosis
Lai, Y.; Tuvim, M.; Leitz, J.; Peters, J. J.; Pfuetzner, R.; Esquivies, L.; Zhou, Q.; Czako, B.; Cross, J.; Jones, P.; Dickey, B.; Brunger, A. T.
10.1101/2022.03.21.484632 — pharmacology and toxicology — Posted on 2022-05-11
2737 In situ identification of secondary structures in unpurified Bombyx mori silk fibrils using polarized two-dimensional infrared spectroscopy
Giubertoni, G.; Caporaletti, F.; Roeters, S. J.; Chatterley, A. S.; Weidner, T.; Laity, P.; Holland, C.; Woutersen, S.
10.1101/2022.05.11.491460 — biophysics — Posted on 2022-05-11
2739 Genome assembly and analysis of the flavonoid and phenylpropanoid biosynthetic pathways in Fingerroot ginger (Boesenbergia rotunda)
Taheri, S.; Teo, C. H.; Heslop-Harrison, J.; Schwarzacher, T.; Tan, Y. S.; Wee, W. Y.; Khalid, N.; Biswas, M. K.; Mutha, N. V. R.; Mohd-Yusof, Y.; Gan, H. M.; Harikrishna, J. A.
10.1101/2022.05.11.491478 — genomics — Posted on 2022-05-11
2742 Shared and distinctive neighborhoods of emerin and LBR revealed by proximity labeling and quantitative proteomics
Cheng, L.-C.; Zhang, X.; Abhinav, K.; Nguyen, J. A.; Baboo, S.; Martinez-Bartolomé, S.; Branon, T. C.; Ting, A. Y.; Loose, E.; Yates, J. R.; Gerace, L.
10.1101/2022.05.11.491529 — cell biology — Posted on 2022-05-11
2745 Botrytis cinerea identifies host plants via the recognition of antifungal capsidiol to induce expression of a specific detoxification gene
Kuroyanagi, T.; Bulasag, A.; Fukushima, K.; Suzuki, T.; Tanaka, A.; Camagna, M.; Sato, I.; Chiba, S.; Ojika, M.; Takemoto, D.
10.1101/2022.05.11.490027 — microbiology — Posted on 2022-05-11
2749 SbCYP79A61 Produces Phenylacetaldoxime, a Precursor of Benzyl Cyanide and Phenylacetic Acid in Sorghum bicolor
Perez, V.; Dai, R.; Tomiczek, B.; Mendoza, J.; Wolf, E.; Grenning, A.; Vermerris, W.; Block, A.; Kim, J.
10.1101/2022.05.11.491506 — plant biology — Posted on 2022-05-11
2750 Long-term ecological and evolutionary dynamics in the gut microbiomes of carbapenemase-producing Enterobacteriaceae colonized subjects
Kang, J. T. L.; Teo, J.; Bertrand, D.; Ng, A.; Ravikrishnan, A.; Yong, M.; Ng, O. T.; Marimuthu, K.; Chen, S.; Chng, K. R.; Gan, Y.-H.; Nagarajan, N.
10.1101/2022.05.11.491472 — genomics — Posted on 2022-05-11
2756 Opiate responses are controlled by interactions of Oprm1 and Fgf12 loci in the murine BXD family: Correspondence to human GWAS findings
Lemen, P. M.; Hatoum, A. S.; Dickson, P. E.; Mittleman, G.; Agrawal, A.; Reiner, B. C.; Berrettini, W.; Ashbrook, D. G.; Gunturkun, H.; Mulligan, M. K.; Williams, R. W.; Chen, H.
10.1101/2022.03.11.483993 — genetics — Posted on 2022-05-11
2758 Lymphatic endothelium arises directly from specialized angioblasts
Lupu, I.-E.; Kirschnick, N.; Weischer, S.; Martinez-Corral, I.; Forrow, A.; Lahmann, I.; Riley, P. R.; Zobel, T.; Makinen, T.; Kiefer, F.; Stone, O. A.
10.1101/2022.05.11.491403 — developmental biology — Posted on 2022-05-11
2760 An expanding arsenal of immune systems that protect bacteria from phages
Millman, A.; Melamed, S.; Leavitt, A.; Doron, S.; Bernheim, A.; Hör, J.; Lopatina, A.; Ofir, G.; Hochhauser, D.; Stokar-Avihail, A.; Tal, N.; Sharir, S.; Voichek, M.; Erez, Z.; Ferrer, J. L. M.; Dar, D.; Kacen, A.; Amitai, G.; Sorek, R.
10.1101/2022.05.11.491447 — microbiology — Posted on 2022-05-11
2765 What the book of Lambda did not tell us about lysogens from natural populations
Berryhill, B. A.; Garcia, R.; McCall, I. C.; Chaudhry, W.; Petite, M.-A.; Levin, B. R.
10.1101/2022.05.11.491505 — evolutionary biology — Posted on 2022-05-11
2768 Mitotic chromosome condensation resets chromatin to maintain transcriptional homeostasis
Ramos-Alonso, L.; Holland, P.; Le Gras, S.; Zhao, X.; Jost, B.; Bjoras, M.; Barral, Y.; Enserink, J. M.; Chymkowitch, P.
10.1101/2022.05.11.491439 — molecular biology — Posted on 2022-05-11
2769 Biosynthetic proteins targeting the SARS-CoV-2 spike as anti-virals
Thebault, S.; Lejal, N.; Dogliani, A.; Donchet, A.; Urvoas, A.; Valerio-Lepiniec, M.; Lavie, M.; Baronti, C.; Touret, F.; da Costa, B.; Bourgon, C.; Fraysse, A.; Saint-Albin-Deliot, A.; Morel, J.; Klonjkowski, B.; de Lamballerie, X.; Dubuisson, J.; Roussel, A.; Minard, P.; Le Poder, S.; Meunier, N.; Delmas, B.
10.1101/2022.05.10.491295 — microbiology — Posted on 2022-05-11
2771 Delayed antigen-specific CD4+ T cell induction correlates with impaired immune responses to SARS-COV-2 mRNA vaccination in the elderly
Jo, N.; Hidaka, Y.; Kikuchi, O.; Fukahori, M.; Sawada, T.; Aoki, M.; Yamamoto, M.; Nagao, M.; Morita, S.; Nakajima, T. E.; Muto, M.; Hamazaki, Y.
10.1101/2022.05.10.490700 — immunology — Posted on 2022-05-11
2772 Three-dose vaccination-induced immune responses protect against SARS-CoV-2 Omicron-BA.2
Zhou, R.; Liu, N.; Li, X.; Peng, Q.; Yiu, C.-K.; Huang, H.; Yang, D.; Du, Z.; Kwok, H.-Y.; Au, K.-K.; Cai, J.-P.; Hung, I. F.-N.; To, K. K.-W.; Xu, X.; Yuen, K.-Y.; Chen, Z.
10.1101/2022.05.09.491254 — immunology — Posted on 2022-05-11
2773 Systematic optimization of Cas12a base editors in wheat and maize using the ITER platform
Gaillochet, C.; Pena Fernandez, A.; Goossens, V.; D'Halluin, K.; Drozdzecki, A.; Shafie, M.; Van Duyse, J.; Van Isterdael, G.; Gonzalez, C.; Vermeersch, M.; De Saeger, J.; Develtere, W.; Audenaert, D.; De Vleesschauwer, D.; Meulewaeter, F.; Jacobs, T. B.
10.1101/2022.05.11.491340 — synthetic biology — Posted on 2022-05-11
2775 Integrated Single-Cell Genotyping and Chromatin Accessibility Charts JAK2V617F Human Hematopoietic Differentiation
Myers, R. M.; Izzo, F.; Kottapalli, S.; Prieto, T.; Dunbar, A.; Bowman, R. L.; Mimitou, E. P.; Stahl, M.; El Ghaity-Beckley, S.; Arandela, J.; Raviram, R.; Ganesan, S.; Mekerishvili, L.; Hoffman, R.; Chaligne, R.; Abdel-Wahab, O.; Smibert, P.; Marcellino, B.; Levine, R. L.; Landau, D. A.
10.1101/2022.05.11.491515 — cancer biology — Posted on 2022-05-11
2777 Disease classification for whole blood DNA methylation: meta-analysis, missing values imputation, and XAI
Kalyakulina, A.; Yusipov, I.; Bacalini, M. G.; Franceschi, C.; Vedunova, M.; Ivanchenko, M.
10.1101/2022.05.10.491404 — bioinformatics — Posted on 2022-05-11
2779 Dual control of meiotic crossover patterning
Durand, S.; Lian, Q.; Jing, J.; Ernst, M.; Grelon, M.; Zwicker, D.; mercier, r.
10.1101/2022.05.11.491364 — genetics — Posted on 2022-05-11
2781 Clones on the run - the genomics of a recently expanded facultative asexual species
Pereyra, R. T.; Rafajlovic, M.; De Wit, P.; Pinder, M.; Kinnby, A.; Töpel, M.; Johannesson, K.
10.1101/2022.05.11.491277 — evolutionary biology — Posted on 2022-05-11
2782 Mutual repression between JNK/AP-1 and JAK/STAT stratifies cell behaviors during tissue regeneration
Jaiswal, J.; Engesser, R.; Peyroton, A.; Weichselberger, V.; Crucianelli, C.; Grass, I.; Timmer, J.; Classen, A.-K.
10.1101/2022.05.11.491445 — developmental biology — Posted on 2022-05-11
2783 DINAVID: A Distributed and Networked Image Analysis System for Volumetric Image Data
Han, S.; Chen, A.; Lee, S.; Fu, C.; Yang, C.; Wu, L.; Winfree, S.; El-Achkar, T. M.; Dunn, K. W.; Salama, P.; Delp, E. J.
10.1101/2022.05.11.491511 — cell biology — Posted on 2022-05-11
2789 Natural variation in the irld gene family affects starvation resistance in C. elegans
Webster, A. K.; Chitrakar, R.; Powell, M.; Chen, J.; Fisher, K.; Tanny, R.; Stevens, L.; Evans, K.; Wei, A.; Antoshechkin, I.; Andersen, E. C.; Baugh, L. R.
10.1101/2021.06.07.447366 — genetics — Posted on 2022-05-11
2790 How many sirtuin genes are out there? evolution of sirtuin genes in vertebrates with a description of a new family member
Opazo, J. C.; Vandewege, M.; Hoffmann, F. G.; Zavala, K.; Melendez, C.; Luchsinger, C.; Cavieres, V.; Vargas-Chacoff, L.; Morera, F.; Burgos, P.; Tapia-Rojas, C.; Mardones, G.
10.1101/2020.07.17.209510 — evolutionary biology — Posted on 2022-05-11
2791 Single cell transcriptomics identifies conserved regulators of neurosecretory lineages
Steger, J.; Cole, A. G.; Denner, A.; Lebedeva, T.; Genikhovich, G. G.; Ries, A.; Reischl, R.; Taudes, E.; Lassnig, M.; Technau, U.
10.1101/2022.05.11.491463 — developmental biology — Posted on 2022-05-11
2793 Inner hair cell synapse density influences auditory processing
Ji, L.; Borges, B. C.; Martel, D. T.; Wu, C.; Liberman, M. C.; Shore, S. E.; Corfas, G.
10.1101/2022.05.02.490340 — neuroscience — Posted on 2022-05-11
2798 Genomic patterns of malignant peripheral nerve sheath tumour (MPNST) evolution correlate with clinical outcome and are detectable in cell-free DNA
Cortes-Ciriano, I.; Steele, C. D.; Piculell, K. G.; Al-Ibraheemi, A.; Eulo, V.; Bui, M. M.; Chatzipli, A.; Dickson, B. C.; Borcherding, D. C.; Feber, A.; Galor, A.; Hart, J.; Jones, K. B.; Jordan, J. T.; Kim, R. H.; Lindsay, D.; Miller, C.; Nishida, Y.; Proszek, P.; Serrano, J.; Sundby, R. T.; Szymanski, J. J.; Ullrich, N. J.; Viskochil, D.; Wang, X.; Snuderl, M.; Park, P. J.; Flanagan, A. M.; Hirbe, A. C.; Pillay, N.; Miller, D. T.
10.1101/2022.05.03.490481 — cancer biology — Posted on 2022-05-11
2799 Spatiotemporal transcriptomics reveals pathogenesis of viral myocarditis
Mantri, M.; Hinchman, M. M.; McKellar, D. W.; Wang, M. F. Z.; Cross, S. T.; Parker, J. S. L.; De Vlaminck, I.
10.1101/2021.12.07.471659 — genomics — Posted on 2022-05-11
2802 A Multi-Omics and Bioenergetics Longitudinal Aging Dataset in Primary Human Fibroblasts with Mitochondrial Perturbations
Sturm, G.; Monzel, A. S.; Karan, K. R.; Michelson, J.; Ware, S. A.; Cardenas, A.; Lin, J.; Bris, C.; Santhanam, B.; Murphy, M. P.; Levine, M. E.; Horvath, S.; Belsky, D. W.; Wang, S.; Procaccio, V.; Kaufman, B. A.; Hirano, M.; Picard, M.
10.1101/2021.11.12.468448 — cell biology — Posted on 2022-05-11
2805 Immediate myeloid depot for SARS-CoV-2 in the human lung
Magnen, M.; You, R.; Rao, A. A.; Davis, R. T.; Rodriguez, L.; Simoneau, C. R.; Hysenaj, L.; Hu, K. H.; The UCSF COMET Consortium, ; Love, C.; Woodruff, P. G.; Erle, D. J.; Hendrickson, C. M.; Calfee, C. S.; Matthay, M. A.; Roose, J. P.; Sil, A.; Ott, M.; Langelier, C. R.; Krummel, M. F.; Looney, M. R.
10.1101/2022.04.28.489942 — immunology — Posted on 2022-05-11
2806 Rearrangement of T Cell Genome ArchitectureRegulates GVHD
Sun, Y.; Dotson, G. A.; Muir, L. A.; Ronquist, S.; Oravecz-Wilson, K.; Peltier, D.; Seike, K.; Li, L.; Meixner, W.; Rajapakse, I.; Reddy, P.
10.1101/2021.01.23.427857 — immunology — Posted on 2022-05-11
2807 Probing effects of the SARS-CoV-2 E protein on membrane curvature and intracellular calcium
Mehregan, A.; Perez-Conesa, S.; Zhuang, Y.; Elbahnsi, A.; Pasini, D.; Lindahl, E.; Howard, R. J.; Ulens, C.; Delemotte, L.
10.1101/2021.05.28.446179 — biophysics — Posted on 2022-05-11
2808 Dynamic in situ confinement triggers ligand-free neuropeptide receptor signaling
Sanchez, M. F.; Dietz, M. S.; Müller, U.; Weghuber, J.; Gatterdam, K.; Wieneke, R.; Heilemann, M.; Lanzerstorfer, P.; Tampe, R.
10.1101/2021.12.15.472742 — biophysics — Posted on 2022-05-11
2812 An in vivo and in silico evaluation of the magical hepatoprotective potentialities of Gynura procumbens: a promising agent for combating hepatotoxicity
Tithi, T. I.; Tahsin, M. R.; Zaman, T. S.; Anjum, J.; Bahar, N. B.; Sen, P.; Tasnim, S.; Sultana, A.; Koly, F. J.; Jahan, I.; Aktar, F.; Chowdhury, J. A.; Kabir, S.; Chowdhury, A. A.; Amran, M. S.
10.1101/2022.05.11.491443 — bioinformatics — Posted on 2022-05-11
2813 Multiple omic investigations of freeze tolerance adaptation in the aquatic ectothermic vertebrate, the Amur sleeper
Lv, W.; Jiang, H.; Qian, Y.; Meng, M.; Wang, C.; Sun, N.; Lu, Y.; Bing, H.; Fang, C.; Irwin, D. M.; He, S.; Yang, L.
10.1101/2022.05.10.491133 — evolutionary biology — Posted on 2022-05-11
2816 Sex differences in islet stress responses support female beta cell resilience
Brownrigg, G. P.; Xia, Y. H.; Jamie Chu, C. M.; Wang, S.; Chao, C.; Zhang, J. A.; Skovso, S.; Panzhinskiy, E.; Hu, X.; Johnson, J. D.; Rideout, E. J.
10.1101/2022.05.10.491428 — cell biology — Posted on 2022-05-11
2817 The association of MEG3 lncRNA with nuclear speckles in living cells
Hasenson, S.; Alkalay, E.; Atrash, M. K.; Boocholez, A.; Gershbaum, J.; Hochberg-Laufer, H.; Shav-Tal, Y.
10.1101/2022.05.11.491451 — cell biology — Posted on 2022-05-11
2818 MAP1LC3C regulates lysosomal exocytosis and induces zinc reprogramming in renal cancer cells
Verma, R.; Aggarwal, P.; Reigle, J.; Secic, D.; Czyzyk-Krzeska, M. F.; Wetzel, C.; Bischoff, M. E.; VandenHeuvel, K.; Biesiada, J.; Ehmer, B.; Landero Figueroa, J. A.; Plas, D. R.; Medvedovic, M.; Meller, J.
10.1101/2022.05.11.491473 — cell biology — Posted on 2022-05-11
2822 Novel mechanism of hypoxic neuronal injury mediated by non-excitatory amino acids and astroglial swelling
Alvarez-Merz, I.; Fomitcheva, I. V.; Sword, J.; Hernandez-Guijo, J. M.; Solis, J. M.; Kirov, S. A.
10.1101/2022.05.10.491362 — neuroscience — Posted on 2022-05-11
2830 BigNeuron: A resource to benchmark and predict best-performing algorithms for automated reconstruction of neuronal morphology
Manubens-Gil, L.; Zhou, Z.; Chen, H.; Ramanathan, A.; Liu, X.; Liu, Y.; Bria, A.; Gillette, T.; Ruan, Z.; Yang, J.; Radojevic, M.; Zhao, T.; Cheng, L.; Qu, L.; Liu, S.; Bouchard, K. E.; Gu, L.; Cai, W.; Ji, S.; Roysam, B.; Wang, C.-W.; Yu, H.; Sironi, A.; Iascone, D. M.; Zhou, J.; Bas, E.; Conde-Sousa, E.; Aguiar, P.; Li, X.; Li, Y.; Nanda, S.; Wang, Y.; Muresan, L.; Fua, P.; Ye, B.; He, H.-y.; Staiger, J. F.; Peter, M.; Cox, D. N.; Simonneau, M.; Oberlaender, M.; Jefferis, G.; Ito, K.; Gonzalez-Bellido, P.; Kim, J.; Rubel, E.; Cline, H. T.; Zeng, H.; Nern, A.; Chiang, A.-S.; Yao, J.; Roskams,
10.1101/2022.05.10.491406 — bioinformatics — Posted on 2022-05-11
2832 An in silico genome-wide screen for circadian clock strength in human samples
Wu, G.; Ruben, M. D.; Francey, L. J.; Lee, Y.; Anafi, R. C.; Hogenesch, J. B.
10.1101/2022.05.10.491250 — bioinformatics — Posted on 2022-05-11
2835 Identification of transcriptional network disruptions in drug-resistant prostate cancer with TraRe
Blatti, C.; De la Fuente, J.; Gao, H.; Marin, I.; Chen, Z.; Zhao, S. D.; Tan, W.; Weinshilboum, R. M.; Kalari, K. R.; Wang, L.; Hernaez, M.
10.1101/2022.05.10.491360 — bioinformatics — Posted on 2022-05-11
2837 Classification of Extracellular Vesicles based on Surface Glycan Structures by Spongy-like Separation Media
Kanao, E.; Wada, S.; Nishida, H.; Kubo, T.; Tanigawa, T.; Imami, K.; Shimoda, A.; Umezaki, K.; Sasaki, Y.; Akiyoshi, K.; Adachi, J.; Otsuka, K.; Ishihama, Y.
10.1101/2022.05.10.491426 — biochemistry — Posted on 2022-05-11
2840 Epigenetic variation impacts ancestry-associated differences in the transcriptional response to influenza infection
Aracena, K. A.; Lin, Y.-L.; Luo, K.; Pacis, A.; Gona, S.; Mu, Z.; Yotova, V.; Sindeaux, R.; Pramatarova, A.; Simon, M.-M.; Chen, X.; Groza, C.; Lougheed, D.; Gregoire, R.; Brownlee, D.; Li, Y.; He, X.; Bujold, D.; Pastinen, T.; Bourque, G.; Barreiro, L. B.
10.1101/2022.05.10.491413 — genetics — Posted on 2022-05-11
2843 A long non-coding RNA is a key factor in the evolution of insect eusociality
Cardoso Junior, C. A. M.; Tiberio, G. J.; Lago, D. C.; Vieira, L. C.; Rosa, J. C.; Paschoal, A. R.; Ronai, I.; Oldroyd, B. P.; Hartfelder, K. H.
10.1101/2022.05.10.491402 — evolutionary biology — Posted on 2022-05-11
2844 Inferring future changes in gene flow under climate change in riverscapes
Nakajima, S.; Suzuki, H.; Nakatsugawa, M.; Matsuo, A.; Hirota, S. K.; Suyama, Y.; Nakamura, F.
10.1101/2022.05.10.491062 — ecology — Posted on 2022-05-11
2845 Transformation of coral communities subjected to an unprecedented heatwave is modulated by local disturbance
Baum, J. K.; Claar, D. C.; Tietjen, K. L.; Magel, J. M. T.; Maucieri, D. G.; Cobb, K. M.; McDevitt-Irwin, J. M.
10.1101/2022.05.10.491220 — ecology — Posted on 2022-05-11
2846 Structure and specialization of mycorrhizal networks in phylogenetically diverse tropical communities
Perez-Lamarque, B.; Petrolli, R.; Strullu-Derrien, C.; Strasberg, D.; Morlon, H.; Selosse, M.-A.; Martos, F.
10.1101/2022.05.10.491376 — ecology — Posted on 2022-05-11
2849 Selectively expressed RNA molecules: a new dimension infunctionalized cell targeting
Hoffmann, M.; Schuele, S.; Hoffmann, C.; Rastfeld, F.; Gerlach, S.; Hersch, N.; Walter, H. L.; Wiedermann, D.; Fink, G. R.; Merkel, R.; Bohlen, H.; Rueger, M. A.; Hoffmann, B.
10.1101/2022.05.10.491309 — cell biology — Posted on 2022-05-11
2850 Extending of imaging volume in soft x-ray tomography
Ekman, A.; Chen, J.-H.; Vanslembrouck, B.; Larabell, C. A.; Le Gros, M. A.; Weinhardt, V.
10.1101/2022.05.11.491437 — cell biology — Posted on 2022-05-11
2852 mTORC2 contributes to murine systemic autoimmunity
Zhou, X.; Qi, H.; Li, M.; Li, Y.; Zhu, X.; Amin, S.; Mariam, A.; Diadhiou, C.; Davidson, A.; Zeng, H.
10.1101/2021.03.27.437347 — immunology — Posted on 2022-05-11
2854 Saccade-related modulation of oscillatory activity in primary auditory cortex
Barczak, A.; O'Connell, M. N.; McGinnis, T.; Mackin, K.; Schroeder, C. E.; Lakatos, P.
10.1101/2022.05.10.491383 — neuroscience — Posted on 2022-05-11
2855 Velocity-based optoretinography for clinical applications
Vienola, K. V.; Valente, D.; Zawadzki, R. J.; Jonnal, R. S.
10.1101/2022.05.10.491416 — neuroscience — Posted on 2022-05-11
2857 Novel tumorigenic FOXM1-PTAFR-PTAF axis revealed by multi-omic profiling in TP53/CDKN2A-double knockout human gastroesophageal junction organoid model
Zhao, H.; Cheng, Y.; Kalra, A.; Ma, K.; Zheng, Y.; Ziman, B.; Tressler, C.; Glunde, K.; Shin, E. J.; Ngamruengphong, S.; Khashab, M.; Singh, V.; Anders, R. A.; Jit, S.; Wyhs, N.; Chen, W.; Li, X.; Lin, D.-c.; Meltzer, S. J.
10.1101/2022.05.10.491356 — cancer biology — Posted on 2022-05-11
2860 High resolution mapping reveals hotspots and sex-biased recombination in Populus trichocarpa
Abeyratne, C. R.; Macaya-Sanz, D.; Zhou, R.; Barry, K. W.; Daum, C.; Haiby, K.; Lipzen, A.; Stanton, B.; Yoshinaga, Y.; Zane, M.; Tuskan, G. A.; DiFazio, S. P.
10.1101/2022.05.10.491397 — genetics — Posted on 2022-05-11
2863 Machine learning directed organoid morphogenesis uncovers an excitable system driving human axial elongation
Anand, G.; Megale, H. C.; Murphy, S. H.; Weis, T.; Lin, Z.; He, Y.; Wang, X.; Liu, J.; Ramanathan, S.
10.1101/2022.05.10.491358 — developmental biology — Posted on 2022-05-11
2864 Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier
Tran, N. L.; Ferreira, L. M.; Alvarez-Moya, B.; Buttiglione, V.; Ferrini, B.; Zordan, P.; Monestiroli, A.; Fagioli, C.; Bezzecchi, E.; Scotti, G. M.; Esposito, A.; Leone, R.; Gnasso, C.; Brendolan, A.; Guidotti, L. G.; Sitia, G.
10.1101/2022.05.10.491298 — cancer biology — Posted on 2022-05-11
2865 Covert attention to obstacles biases zebrafish escape direction
Zwaka, H.; McGinnis, O. J.; Pflitsch, P.; Prabha, S.; Mansinghka, V.; Engert, F.; Bolton, A. D.
10.1101/2022.04.14.488363 — animal behavior and cognition — Posted on 2022-05-11
2867 A quantitative map of nuclear pore assembly reveals two distinct mechanisms
Otsuka, S.; Tempkin, J. O. B.; Zhang, W.; Politi, A. Z.; Rybina, A.; Hossain, M. J.; Kueblbeck, M.; Callegari, A.; Koch, B.; Sali, A.; Ellenberg, J.
10.1101/2021.05.17.444137 — cell biology — Posted on 2022-05-11
2868 Macrophages inhibit Coxiella burnetii by the ACOD1-itaconate pathway for containment of Q fever
Kohl, L.; Siddique, N. A. A.; Bodendorfer, B.; Berger, R.; Preikschat, A.; Daniel, C.; Oelke, M.; Mauermeir, M.; Yang, K.-T.; Hayek, I.; Szperlinski, M.; Schulze-Luehrmann, J.; Schleicher, U.; Bozec, A.; Kroenke, G.; Murray, P. J.; Yamamoto, M.; Schatz, V.; Jantsch, J.; Oefner, P.; Degrandi, D.; Pfeffer, K.; Rauber, S.; Bogdan, C.; Dettmer, K.; Luhrmann, A.; Lang, R.
10.1101/2022.05.10.491306 — immunology — Posted on 2022-05-11
2870 A compromise between Tgfβ and Egfr signaling programs confers the ability to lead heterogeneous collective invasion
Nasir, A.; Camacho, S.; McIntosh, A. T.; Graham, G. T.; Rahhal, R.; Huysman, M. E.; Riegel, A. T.; Pearson, G. W.
10.1101/2020.11.14.383232 — cancer biology — Posted on 2022-05-11
2871 BET Inhibitors Target the SCLC-N subtype Small Cell Lung Cancer by Blocking NEUROD1 Transactivation
Chen, H.; Gesumaria, L.; Park, Y.-K.; Oliver, T. G.; Singer, D. S.; Ge, K.; Schrump, D. S.
10.1101/2021.10.25.465771 — cancer biology — Posted on 2022-05-11
2872 Covalent Disruptor of YAP-TEAD Association Suppresses Defective Hippo Signaling
Fan, M.; Lu, W.; Che, J.; Kwiatkowski, N. P.; Gao, Y.; Seo, H.-S.; Ficarro, S. B.; Gokhale, P. C.; Liu, Y.; Geffken, E. A.; Lakhani, J.; Song, K.; Kuljanin, M.; Ji, W.; Jiang, J.; He, Z.; Tse, J.; Boghossian, A. S.; Rees, M. G.; Ronan, M. M.; Roth, J. A.; Mancias, J. D.; Marto, J. A.; Dhe-Paganon, S.; Zhang, T.; Gray, N.
10.1101/2022.05.10.491316 — cancer biology — Posted on 2022-05-11
2873 CRISPR-Detector: Fast and Accurate Detection, Visualization, and Annotation of Genome Wide Mutations Induced by Gene Editing Events
Huang, L.; Wang, D.; Chen, H.; Hu, J.; Dai, X.; Liu, C.; Li, A.; Shen, X.; Qi, C.; Sun, H.; Zhang, D.; Chen, T.; Jiang, Y.
10.1101/2022.02.16.480781 — bioinformatics — Posted on 2022-05-11
2874 Drug-like small molecules that inhibit expression of the oncogenic microRNA-21
Shortridge, M. D.; Chaubey, B.; Zhang, H. J.; Pavelitz, T.; Olsen, G. L.; Calin, G.; Varani, G.
10.1101/2022.04.30.490150 — biochemistry — Posted on 2022-05-11
2875 Normal mammary epithelia accumulate DNA methylation changes with age that are consistent with breast cancer methylomes
Senapati, P.; Miyano, M.; Sayaman, R. W.; Basam, M.; Trac, C.; Leung, A.; LaBarge, M. A.; Schones, D. E.
10.1101/2020.06.26.170043 — genomics — Posted on 2022-05-11
2876 Tissue-specific impacts of aging and genetics on gene expression patterns in humans
Yamamoto, R.; Chung, R.; Vazquez, J. M.; Sheng, H.; Steinberg, P.; Ioannidis, N.; Sudmant, P. H.
10.1101/2021.11.16.468753 — genetics — Posted on 2022-05-11
2879 Polaramycin B, and not physical interaction, is the signal that rewires fungal metabolism in the Streptomyces - Aspergillus interaction.
Berger, H.; Bacher, M.; Labuda, R.; Eppel, I. M.; Bayer, F.; Sulyok, M.; Gasparotto, E.; Zehetbauer, F.; Doppler, M.; Gratzl, H.; Strauss, J.
10.1101/2022.05.04.490618 — microbiology — Posted on 2022-05-11
2880 Competition and coevolution drive the evolution and the diversification of CRISPR immunity
Guillemet, M.; Chabas, H.; Nicot, A.; Gatchitch, F.; Ortega-Abboud, E.; Buus, C.; Hindhede, L.; Rousseau, G. M.; Bataillon, T.; Moineau, S.; Gandon, S.
10.1101/2021.11.12.468349 — microbiology — Posted on 2022-05-11
2881 Mast cell-mediated inflammation relies on insulin-regulated aminopeptidase controlling cytokine export from the Golgi
Weimershaus, M.; Carvalho, C.; Enee, E.; Rignault, R.; Dussiot, M.; van Endert, P.; Maciel, T. T.; Hermine, O.
10.1101/2022.01.21.477149 — immunology — Posted on 2022-05-11
2882 Quantifying dynamic facial expressions under naturalistic conditions
Jeganathan, J.; Campbell, M.; Hyett, M.; Parker, G.; Breakspear, M.
10.1101/2022.05.08.490793 — neuroscience — Posted on 2022-05-11
2883 On the topochronic map of the human brain dynamics
Sorrentino, P.; Petkoski, S.; Sparaco, M.; Troisi Lopez, E.; Signoriello, E.; Baselice, F.; Bonavita, S.; Pirozzi, M. A.; Quarantelli, M.; Sorrentino, G.; Jirsa, V.
10.1101/2021.07.01.447872 — neuroscience — Posted on 2022-05-11
2884 Configurable Compartmentation Enables In vitro Reconstitution of Sustained Synthetic Biology Systems
Li, L.; Zhang, R.; Tian, X.; Li, T.; Pu, B.; Ma, C.; Ba, F.; Xiong, C.; Shi, Y.; Li, J.; Keasling, J.; Zhang, J.; Liu, Y.
10.1101/2022.03.19.484972 — synthetic biology — Posted on 2022-05-11
2888 MRI Guided Fresh Tissue Procurement in Radical Prostatectomy Specimens: An Evolutionary Paradigm
Freidlin, R. Z.; Krynitsky, J.; Bastian, C.; Schultz, C.; Custer, J.; Young, S.; Mehralivand, S.; Merino, M. J.; Valera, V. A.; Pinto, P.; Turkbey, B.; Choyke, P. L.; Pohida, T. J.; Garmendia, M. A.
10.1101/2022.05.09.491189 — bioengineering — Posted on 2022-05-11
2889 A Multi-Omics and Bioenergetics Longitudinal Aging Dataset in Primary Human Fibroblasts with Mitochondrial Perturbations
Sturm, G.; Monzel, A. S.; Karan, K. R.; Michelson, J.; Ware, S. A.; Cardenas, A.; Lin, J.; Bris, C.; Santhanam, B.; Murphy, M. P.; Levine, M. E.; Horvath, S.; Belsky, D. W.; Wang, S.; Procaccio, V.; Kaufman, B. A.; Hirano, M.; Picard, M.
10.1101/2021.11.12.468448 — cell biology — Posted on 2022-05-11
2893 A neural code for spatiotemporal context
Schonhaut, D. R.; Aghajan, Z. M.; Kahana, M. J.; Fried, I.
10.1101/2022.05.10.491339 — neuroscience — Posted on 2022-05-11
2897 A molecular phenology scale of fruit development
Tornielli, G. B.; Sandri, M.; Fasoli, M.; Amato, A.; Pezzotti, M.; Zuccolotto, P.; Zenoni, S.
10.1101/2022.05.10.491408 — plant biology — Posted on 2022-05-10
2899 Bcl-xL is a key mediator of apoptosis following KRASG12C inhibition in KRASG12C mutant colorectal cancer.
Khawaja, H.; Briggs, R.; Latimer, C.; Rassel, M.; Griffin, D.; Hanson, L.; Bardelli, A.; Di Nicolantonio, F.; McDade, S. S.; Scott, C. J.; Lambe, S.; Maurya, M.; Lindner, A. U.; Prehn, J. H. M.; Sousa, J.; Winnington, C.; LaBonte, M. J.; Ross, S.; Van Schaeybroeck, S.
10.1101/2022.05.10.491367 — cancer biology — Posted on 2022-05-10
2901 Structural basis of DNA packaging by a ring-type ATPase from an archetypal viral system
Fung, H. K. H.; Grimes, S.; Huet, A.; Duda, R. L.; Chechik, M.; Gault, J.; Robinson, C. V.; Hendrix, R. W.; Jardine, P. J.; Conway, J. F.; Baumann, C. G.; Antson, A. A.
10.1101/2022.05.10.491410 — biochemistry — Posted on 2022-05-10
2902 Reconstruction of Full-length scFv Libraries with the Extended Range Targeted Sequencing Method
Wei, C.; Criner, S.; Sridhar, B.; Shultzaberger, R.; Looney, T.; Fabani, M. M.; Glezer, E. N.
10.1101/2022.05.10.491248 — genomics — Posted on 2022-05-10
2904 Human platelet lysate derived extracellular vesicles enhance angiogenesis through miR-126
De Falco, E.; Bordin, A.; Chirivi, M.; Pagano, F.; Milan, M.; Iuliano, M.; Scaccia, E.; Fortunato, O.; Mangino, G.; Dhori, X.; De Marinis, E.; D'Amico, A.; Miglietta, S.; Picchio, V.; Rizzi, R.; Romeo, G.; Pulcinelli, F.; Chimenti, I.; Frati, G.
10.1101/2022.05.10.491341 — cell biology — Posted on 2022-05-10
2908 Transposable elements are associated with the variable response to influenza infection
Chen, X.; Pacis, A. S.; Aracena, K. A.; Gona, S.; Kwan, T.; Groza, C.; Lin, Y. L.; Sindeaux, R. H. M.; Yotova, V.; Pramatarova, A.; Simon, M.-M.; Pastinen, T. M.; Barreiro, L. B.; Bourque, G.
10.1101/2022.05.10.491101 — immunology — Posted on 2022-05-10
2911 A multiscale spatiotemporal model including a switch from aerobic to anaerobic metabolism reproduces succession in the early infant gut microbiota
Versluis, D. M.; Schoemaker, R.; Looijesteijn, E.; Muysken, D.; Jeurink, P. V.; Paques, M.; Geurts, J. M. W.; Merks, R. M. H.
10.1101/2021.08.22.457032 — systems biology — Posted on 2022-05-10
2912 Aberrant regulation of serine metabolite drives extracellular vesicle release and cancer progression
Yamamoto, T.; Nakayama, J.; Urabe, F.; Ito, K.; Kuroda, M.; Hattori, Y.; Yamamoto, Y.; Ochiya, T.
10.1101/2022.05.10.491299 — cancer biology — Posted on 2022-05-10
2913 Mechanism of Curaxin-dependent Nucleosome Unfolding by FACT
Volokh, O.; Sivkina, A.; Moiseenko, A.; Popinako, A.; Karlova, M.; Valieva, M.; Kotova, E.; Kirpichnikov, M.; Formosa, T.; Studitsky, V.; Sokolova, O.
10.1101/2022.05.10.491363 — cancer biology — Posted on 2022-05-10
2915 Computational model of fractal interface formation in bacterial biofilms
Brooks, C.; McCool, J. T.; Gillman, A.; Suel, G. M.; Mugler, A.; Larkin, J. W.
10.1101/2022.05.10.491419 — biophysics — Posted on 2022-05-10
2916 Structure of the SHOC2-MRAS-PP1C complex provides insights into RAF activation and Noonan syndrome
Bonsor, D. A.; Alexander, P.; Snead, K.; Hartig, N.; Drew, M.; Messing, S.; Finci, L. I.; Nissley, D. V.; McCormick, F.; Esposito, D.; Rodriguez-Viciana, P.; Stephen, A. G.; Simanshu, D. K.
10.1101/2022.05.10.491335 — biophysics — Posted on 2022-05-10
2917 Genome sequence assembly evaluation using long-range sequencing data
Guan, D.; McCarthy, S.; Wood, J.; Ning, Z.; Sims, Y.; Chow, W.; Howe, K.; Wang, G.; Wang, Y.; Durbin, R.
10.1101/2022.05.10.491304 — bioinformatics — Posted on 2022-05-10
2918 Activated interstitial macrophages are a predominant target of viral takeover and focus of inflammation in COVID-19 initiation in human lung
Wu, T. T.-H.; Travaglini, K. J.; Rustagi, A.; Xu, D.; Zhang, Y.; Jang, S. K.; Gillich, A.; Dehghannasiri, R.; Martinez-Colon, G.; Beck, A.; Wilk, A. J.; Morri, M.; Trope, W. L.; Shrager, J. B.; Quake, S. R.; Kuo, C. S.; Salzman, J.; Kim, P. S.; Blish, C. A.; Krasnow, M. A.
10.1101/2022.05.10.491266 — genomics — Posted on 2022-05-10
2919 The fidelity of transcription in human cells
Verheijen, M.; Chung, C.; Zhang, X.; Huang, B.; Coakley, A.; McGann, E.; Wade, E.; Dinep-Schneider, O.; LaGosh, J.; Anagnostou, M.-E.; Simpson, S.; Thomas, K.; Ernst, M.; Rattray, A.; Lynch, M.; Kashlev, M.; Benayoun, B. A.; Li, Z.; Strathern, J.; Gout, J.-F.; Vermulst, M.
10.1101/2022.05.10.491385 — genetics — Posted on 2022-05-10
2920 Rapid macropinocytic transfer of α-synuclein to lysosomes
Bayati, A.; Banks, E.; Han, C.; Luo, W.; Reintsch, W. E.; Zorca, C. E.; Shlaifer, I.; Pellitero, E. D. C.; Vanderperre, B.; McBride, H. M.; Fon, E. A.; Durcan, T. A.; McPherson, P. S.
10.1101/2022.01.06.475207 — cell biology — Posted on 2022-05-10
2922 The N-terminal domain of MX1 proteins is essential for their antiviral activity against different families of RNA viruses
McKellar, J.; Arnaud-Arnould, M.; Chaloin, L.; Tauziet, M.; Arpin-Andre, C.; Pourcelot, O.; Blaise, M.; Moncorge, O.; Goujon, C.
10.1101/2022.05.10.491305 — microbiology — Posted on 2022-05-10
2923 A two-hit epistasis model prevents core genome disharmony in recombining bacteria
Taylor, A. J.; Meric, G.; Yahara, K.; Pascoe, B.; Mageiros, L.; Mourkas, E.; Calland, J. K.; Puranen, S.; Hitchings, M. D.; Jolley, K. A.; Kobras, C. M.; Williams, N. J.; van Vliet, A. H.; Parkhill, J.; Maiden, M. C.; Corander, J.; Hurst, L. D.; Falush, D.; Didelot, X.; Kelly, D. J.; Sheppard, S. K.
10.1101/2021.03.15.435406 — microbiology — Posted on 2022-05-10
2924 HIV rapidly targets a diverse pool of CD4+ T cells to establish productive and latent infections
Gantner, P.; Buranapraditkun, S.; Pagliuzza, A.; Dufour, C.; Pardons, M.; Mitchell, J. L.; Kroon, E.; Sacdalan, C.; Tulmethakaan, N.; Pinyakorn, S.; Robb, M. L.; Phanuphak, N.; Ananworanich, J.; Hsu, D.; Vasan, S.; Trautmann, L.; Fromentin, R.; Chomont, N.
10.1101/2022.05.10.491275 — microbiology — Posted on 2022-05-10
2925 COVID-19 mRNA third dose induces a unique hybrid immunity-like antibody response
Andreano, E.; Paciello, I.; Pierleoni, G.; Piccini, G.; Abbiento, V.; Antonelli, G.; Pileri, P.; Manganaro, N.; Pantano, E.; Maccari, G.; Marchese, S.; Donnici, L.; Benincasa, L.; Giglioli, G.; Leonardi, M.; De Santi, C.; Fabbiani, M.; Rancan, I.; Tumbarello, M.; Montagnani, F.; Sala, C.; Medini, D.; De Francesco, R.; Montomoli, E.; Rappuoli, R.
10.1101/2022.05.09.491201 — immunology — Posted on 2022-05-10
2926 Immunodominant surface epitopes power immune evasion in the African trypanosome
Gkeka, A.; Aresta-Branco, F.; Triller, G.; Vlachou, E. P.; Lilic, M.; Olinares, P. D. B.; Perez, K.; Chait, B.; Blatnik, R.; Ruppert, T.; Stebbins, C. E.; Papavasiliou, F. N.
10.1101/2021.07.20.453071 — immunology — Posted on 2022-05-10
2928 Entorhinal-hippocampal circuit integrity is related to mnemonic discrimination and amyloid-β pathology in older adults
Adams, J. N.; Kim, S.; Rizvi, B.; Sathishkumar, M.; Taylor, L.; Harris, A. L.; Mikhail, A.; Keator, D. B.; McMillan, L.; Yassa, M. A.
10.1101/2022.05.10.491249 — neuroscience — Posted on 2022-05-10
2931 Molecular Mechanisms of Steric Pressure Generation and Membrane Remodeling by Intrinsically Disordered Proteins
Houser, J. R.; Cho, H. W.; Hayden, C. C.; Yang, N.; Wang, L.; Lafer, E. M.; Thirumalai, D.; Stachowiak, J. C.
10.1101/2022.05.10.491320 — biophysics — Posted on 2022-05-10
2934 Haplotype-resolved assembly of a tetraploid potato genome using long reads and low-depth offspring data
Serra Mari, R.; Schrinner, S.; Finkers, R.; Arens, P.; Schmidt, M. H.- W.; Usadel, B.; Klau, G. W.; Marschall, T.
10.1101/2022.05.10.491293 — genomics — Posted on 2022-05-10
2935 The global importance of fish to the biological carbon pump
Pinti, J.; DeVries, T.; Norin, T.; Serra-Pompei, C.; Proud, R.; Siegel, D. A.; Kiorboe, T.; Petrik, C. M.; Andersen, K. H.; Brierley, A. S.; Visser, A. W.
10.1101/2021.03.22.436489 — ecology — Posted on 2022-05-10
2936 Non-cell-autonomous HSC70.1 chaperone displays homeostatic feed-back regulation by binding its own mRNA
Yang, L.; Zhou, Y.; Wang, S.; Xu, Y.; Ostendorp, S.; Tomkins, M.; Kehr, J.; Morris, R. J.; Kragler, F.
10.1101/2022.05.10.491294 — plant biology — Posted on 2022-05-10
2937 Structures reveal a key mechanism of WAVE Regulatory Complex activation by Rac1 GTPase
Ding, B.; Yang, S.; Schaks, M.; Liu, Y.; Brown, A.; Rottner, K.; Chowdhury, S.; Chen, B.
10.1101/2022.05.10.491380 — biochemistry — Posted on 2022-05-10
2941 Topology of gene regulatory compartments relative to the nuclear matrix
Park, G.; Ryu, K.; Lee, J.; Kim, G.; Park, T. L.; Shim, H.; Lee, Y.; Kim, C.; Cho, W.-K.
10.1101/2022.05.10.491284 — cell biology — Posted on 2022-05-10
2942 Identification of a novel deFADding activity in 5' to 3' exoribonucleases
Sharma, S.; Yang, J.; Doamekpor, S. K.; Grudizen-Nogalska, E.; Tong, L.; Kiledjian, M.
10.1101/2022.05.10.491372 — molecular biology — Posted on 2022-05-10
2945 The neighboring genes AvrLm10A and AvrLm10B are part of a large multigene family of cooperating effector genes conserved in Dothideomycetes and Sordariomycetes
Talbi, N.; Fokkens, L.; Audran, C.; Petit-Houdenot, Y.; Pouzet, C.; Blaise, F.; Gay, E. J.; Rouxel, T.; Balesdent, M.-H.; Rep, M.; Fudal, I.
10.1101/2022.05.10.491286 — plant biology — Posted on 2022-05-10
2948 Extended DNA binding interface beyond the canonical SAP domain contributes to SDE2 function at DNA replication forks
Weinheimer, A.; Paung, Y.; Rageul, J.; Khan, A.; Ho, B.; Tong, M.; Alphonse, S.; Seeliger, M.; Kim, H.
10.1101/2022.05.09.490802 — biochemistry — Posted on 2022-05-10
2951 Chromosome-level genome sequence of the Genetically Improved Farmed Tilapia (GIFT, Oreochromis niloticus) highlights regions of introgression with O. mossambicus
Etherington, G. J.; Nash, W.; Ciezarek, A.; Mehta, T. K.; Barria Gonzalez, A.; Penaloza, C.; Khan, M. G.; Durrant, A.; Forrester, N.; Fraser, F.; Irish, N.; Kaithakottil, G.; Lipscombe, J.; Trong, T.; Watkins, C.; Swarbreck, D.; Angiolini, E.; Cnaani, A.; Gharbi, K.; Houston, R. D.; Benzie, J.; Haerty, W.
10.1101/2022.05.10.490902 — genomics — Posted on 2022-05-10
2957 Mechanochemical rules for membrane-reshaping composite filaments
Meadowcroft, B.; Palaia, I.; Pfitzner, A.-K.; Roux, A.; Baum, B.; Saric, A.
10.1101/2022.05.10.490642 — biophysics — Posted on 2022-05-10
2958 The autism-associated gene SYNGAP1 regulates human cortical neurogenesis
Birtele, M.; Del Dosso, A.; Xu, T.; Nguyen, T.; Wilkinson, B.; Urenda, J.-P.; Knight, G.; Moore, R.; Sharma, R.; Pirrotte, P.; Ashton, R. S.; Huang, E. J.; Coba, M. P.; Quadrato, G.
10.1101/2022.05.10.491244 — developmental biology — Posted on 2022-05-10
2959 Stiffness of primordial germ cells is required for their extravasation in avian embryos
Saito, D.; Tadokoro, R.; Nagasaka, A.; Yoshino, D.; Teramoto, T.; Mizumoto, K.; Funamoto, K.; Kidokoro, H.; Miyata, T.; Tamura, K.; Takahashi, Y.
10.1101/2022.05.09.491122 — developmental biology — Posted on 2022-05-10
2960 Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants
Tan, S.; Hu, X.; Li, Y.; Wu, Z.; Zhao, J.; Lu, G.; Yu, Z.; Du, B.; Liu, Y.; Li, L.; Chen, Y.; Li, Y.; Yao, Y.; Zhang, X.; Rao, J.; Gao, G.; Peng, Y.; Liu, H.; Yuan, Z.; Liu, J.; Wang, Q.; Hu, H.; Gao, X.; Zhou, H.; Yu, H.; Xu, Y.; Yu, W.; Feng, L.; Wang, M.; Shan, C.; Lu, J.; Lin, J.
10.1101/2022.05.10.491301 — immunology — Posted on 2022-05-10
2961 Primate mothers promote proximity between their offspring and infants who look like them
Charpentier, M. J.; Poirotte, C.; Roura-Torres, B.; Amblard-Rambert, P.; Willaume, E.; Kappeler, P. M.; Rousset, F.; Renoult, J. P.
10.1101/2022.05.09.491128 — evolutionary biology — Posted on 2022-05-10
2962 Lifelong regeneration of cerebellar Purkinje neurons after induced cell ablation in zebrafish
Köster, R. W.; Pose-Mendez, S.; Schramm, P.; Winter, B.; Meier, J. C.; Ampatzis, K.
10.1101/2022.05.10.491347 — neuroscience — Posted on 2022-05-10
2963 Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses
Chakrabarti, R.; Jaime Tobon, L. M.; Slitin, L.; Redondo-Canales, M.; Hoch, G.; Slashcheva, M.; Fritsch, E.; Bodensiek, K.; Özcete, O. D.; Gültas, M.; Michanski, S.; Opazo, F.; Neef, J.; Pangrsic, T.; Moser, T.; Wichmann, C.
10.1101/2022.05.10.491334 — neuroscience — Posted on 2022-05-10
2964 The autism-associated gene SYNGAP1 regulates human cortical neurogenesis
Birtele, M.; Birtele, A.; Xu, T.; Nguyen, T.; Wilkinson, B.; Urenda, J.-P.; Knight, G.; Moore, R.; Sharma, R.; Pirrotte, P.; Ashton, R. S.; Huang, E. J.; Quadrato, G.
10.1101/2022.05.10.491244 — developmental biology — Posted on 2022-05-10
2965 SARS-CoV-2 Spike N-Terminal Domain modulates TMPRSS2-dependent viral entry and fusogenicity
Meng, B.; Datir, R.; Choi, J.; CITIID-NIHR BioResource COVID-19 Collaboration, ; Bradley, J.; Smith, K. G.; Lee, J. H.; Gupta, R. K.
10.1101/2022.05.07.491004 — microbiology — Posted on 2022-05-10
2966 Orphan C/D box snoRNAs modulate fear-related memory processes in mice
Leighton, L. J.; Zhao, Q.; Marshall, P. R.; Madugalle, S. U.; Chan, A. H.; Musgrove, M. R. B.; Ren, H.; Periyakaruppiah, A.; Edson, J.; Wei, W.; Li, X.; Spitale, R. C.; Bredy, T. W.
10.1101/2022.05.09.491263 — neuroscience — Posted on 2022-05-10
2967 At a second glance: cognitive and oculomotor neural activity of refixation planning
Nikolaev, A. R.; Ehinger, B. V.; Meghanathan, R. N.; van Leeuwen, C.
10.1101/660308 — neuroscience — Posted on 2022-05-10
2968 Genomic detection of a secondary family burial in a single jar coffin in early Medieval Korea
Lee, D.-N.; Jeon, C. L.; Kang, J.; Burri, M.; Krause, J.; Woo, E. J.; Jeong, C.
10.1101/2022.05.09.491093 — genomics — Posted on 2022-05-10
2969 Reduced injury risk links sociality to survival in a group-living primate
Pavez-Fox, M. A.; Kimock, C. M.; Rivera-Barreto, N.; Negron-Del Valle, J. E.; Phillips, D.; Ruiz-Lambides, A.; Snyder-Mackler, N.; Higham, J. P.; Siracusa, E. R.; Brent, L. J. N.
10.1101/2022.04.05.487140 — evolutionary biology — Posted on 2022-05-10
2972 First report of kdr L1014F and ace-1 G119S insecticide resistance in Belgian Culex (Diptera: Culicidae) mosquitoes
Wang, L.; Soto, A.; Remue, L.; De Coninck, L.; Verwimp, S.; Bouckaert, J.; Vanwinkel, M.; Matthijnssens, J.; Delang, L.
10.1101/2022.02.28.482257 — molecular biology — Posted on 2022-05-10
2974 The synergistic effects of plants and nitrogen on microbial hitchhiking
Liu, Z.; Wang, Z.; Xia, Q.; Zhou, Q.; Wu, X.; Kong, W.; Lei, W.; Zeng, J.; Liu, C.; Wang, Y.; Chang, W.; Li, Z.; Yang, Y.; Yang, L.; Tan, X.
10.1101/2022.05.09.491057 — microbiology — Posted on 2022-05-10
2975 Evolutionary ecology of microbial populations inhabiting deep sea sediments associated with cold seeps
Dong, X.; Peng, Y.; Wang, M.; Woods, L.; Wu, W.; Wang, Y.; Xiao, X.; Li, J.; Jia, K.; Greening, C.; Shao, Z.; Hubert, C. R. J.
10.1101/2022.05.09.490922 — microbiology — Posted on 2022-05-10
2976 Imprinted antibody responses against SARS-CoV-2 Omicron sublineages
Park, Y.-J.; Pinto, D.; Walls, A. C.; Liu, Z.; De Marco, A.; Benigni, F.; Zatta, F.; Silacci-Fregni, C.; Bassi, J.; Sprouse, K. R.; Addetia, A.; Bowen, J. E.; Stewart, C.; Giurdanella, M.; Saliba, C.; Guarino, B.; Schmid, M.; Franko, N.; Logue, J.; Dang, H. V.; di Iulio, J.; Rivera, W.; Schnell, G.; Lempp, F.; Janer, J.; Abdelnabi, R.; Maes, P.; Ferrari, P.; Ceschi, A.; Giannini, O.; de Melo, G.; Kergoat, L.; Bourhy, H.; Neyts, J.; Soriagha, L.; Purcell, L.; Snell, G.; Whelan, S.; Lanzavecchia, A.; Virgin, H.; Piccoli, L.; Chu, H.; Pizzuto, M. S.; Corti, D.; Veesler, D.
10.1101/2022.05.08.491108 — immunology — Posted on 2022-05-10
2977 Adenovirus-Vectored SARS-CoV-2 Vaccine Expressing S1-N Fusion Protein
Khan, M. S.; Kim, E.; McPherson, A.; Weisel, F. J.; Huang, S.; Kenniston, T. W.; Percivalle, E.; Cassaniti, I.; Baldanti, F.; Meisel, M.; Gambotto, A.
10.1101/2022.05.09.491179 — immunology — Posted on 2022-05-10
2978 Age-associated gut microbiota impairs hippocampus-dependent memory in a vagus-dependent manner
Rei, D.; Saha, S.; Haddad, M.; Haider Rubio, A.; Perlaza, B. L.; Ungeheuer, M.-N.; Sokol, H.; Lledo, P.-M.
10.1101/2021.01.28.428594 — neuroscience — Posted on 2022-05-10
2979 Temporal dynamics of neural responses in human visual cortex
Groen, I. I. A.; Piantoni, G.; Montenegro, S.; Flinker, A.; Devore, S.; Devinsky, O.; Doyle, W.; Dugan, P.; Friedman, D.; Ramsey, N.; Petridou, N.; Winawer, J. A.
10.1101/2021.08.08.455547 — neuroscience — Posted on 2022-05-10
2980 Maternal microbiota Bifidobacterium promotes placental morphogenesis, nutrient transport and fetal growth in mice
Lopez-Tello, J.; Schofield, Z.; Kiu, R.; Dalby, M. J.; van Sinderen, D.; Le Gall, G.; Sferruzzi-Perri, A. N.; Hall, L. J.
10.1101/2021.07.23.453407 — physiology — Posted on 2022-05-10
2981 Impact of pre-breeding feeding practices on rabbit mammary gland development at mid-pregnancy.
Hue-Beauvais, C.; Bebin, K.; Robert, R.; Gardan-Salmon, D.; Maupin, M.; Brun, N.; Aujean, E.; Jaffrezic, F.; simon, s.; Charlier, M.; Le Provost, F.
10.1101/2022.01.17.476562 — physiology — Posted on 2022-05-10
2982 Development of Actionable Targets of Multi-kinase Inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells
Denisova, O.; Merisaari, J.; Kaur, A.; Yetukuri, L.; Jumppanen, M.; von Schantz-Fant, C.; Ohlmeyer, M.; Wennerberg, K.; Aittokallio, T.; Taipale, M.; Westermarck, J.
10.1101/2022.01.20.477108 — cancer biology — Posted on 2022-05-10
2986 A guide to designing GPS-based studies of animal societies
He, P.; Klarevas-Irby, J. A.; Papageorgiou, D.; Christensen, C.; Strauss, E. D.; Farine, D. R.
10.1101/2022.01.29.478280 — animal behavior and cognition — Posted on 2022-05-10
2987 Population genomics provide insights into the global genetic structure of Colletotrichum graminicola, the causal agent of maize anthracnose
Rogerio, F.; Baroncelli, R.; Cuevas-Fernandez, F. B.; Becerra, S.; Crouch, J. A.; Bettiol, W.; Azcarate-Peril, M. A.; Malapi-Wight, M.; Ortega, V.; Betran, J.; Tenuta, A.; Dambolena, J. S.; Esker, P. D.; Revilla, P.; Jackson-Ziems, T.; Hiltbrunner, J.; Munkvold, G.; Buhinicek, I.; Vicente-Villardon, J. L.; Sukno, S. A.; Thon, M. R.
10.1101/2022.05.07.490914 — genomics — Posted on 2022-05-10
2994 Centrosome Amplification promotes cell invasion via cell-cell contact disruption and Rap-1 activation
Prakash, A.; Paunikar, S.; Webber, M.; McDermott, E.; Vellanki, S. H.; Thompson, K.; Dockery, P.; Jahns, H.; Brown, J. A. L.; Hopkins, A. M.; Bourke, E.
10.1101/2022.05.09.490051 — cell biology — Posted on 2022-05-10
2998 Attention gain and reorienting in fronto-parietal networks shape human conscious report
Liu, J.; Bayle, D. J.; Spagna, A.; Sitt, J. D.; Bourgeois, A.; Lehongre, K.; Fernandez-Vidal, S.; Navarro, V.; Adam, C.; Lambrecq, V.; Malkinson, T. S.; Bartolomeo, P.
10.1101/2022.04.10.487690 — neuroscience — Posted on 2022-05-10
2999 Mechanosensitive pore opening of a prokaryotic voltage-gated sodium channel
Strege, P. R.; Cowan, L. M.; Alcaino, C.; Mazzone, A.; Ahern, C. A.; Milescu, L. S.; Farrugia, G.; Beyder, A.
10.1101/2022.05.10.491345 — physiology — Posted on 2022-05-10
3000 Single-particle studies of the effects of RNA-protein interactions on the self-assembly of RNA virus particles
Garmann, R. F.; Goldfain, A. M.; Tanimoto, C. R.; Beren, C. E.; Vasquez, F. F.; Knobler, C. M.; Gelbart, W. M.; Manoharan, V. N.
10.1101/2022.05.09.488235 — biophysics — Posted on 2022-05-10
3003 Stardust: improving spatial transcriptomics data analysis through space aware modularity optimization based clustering.
Avesani, S.; Viesi, E.; Alessandrì, L.; Motterle, G.; Bonnici, V.; Beccuti, M.; Calogero, R.; Giugno, R.
10.1101/2022.04.27.489655 — bioinformatics — Posted on 2022-05-10
3006 Chromosome-level genome assembly and annotation of two lineages of the ant Cataglyphis hispanica: steppingstones towards genomic studies of hybridogenesis and thermal adaptation in desert ants
Darras, H.; de Souza Araujo, N.; Baudry, L.; Guiglielmoni, N.; Lorite, P.; Marbouty, M.; Rodriguez, F.; Arkhipova, I.; Koszul, R.; Flot, J.-F.; Aron, S.
10.1101/2022.01.07.475286 — genomics — Posted on 2022-05-10
3007 Diet's impact dictated by synonymous mitochondrial SNP interacting with nucleotype
Dobson, A.; Kumpitsch, L.; Langer, L.; Voigt, E.; Ibrahim, R.; Dowling, D. K.; Reinhardt, K.
10.1101/2021.03.07.434274 — genetics — Posted on 2022-05-10
3009 Spontaneous parthenogenesis in the parasitoid wasp Cotesia typhae: low frequency anomaly or evolving process?
Capdevielle Dulac, C.; Benoist, R.; Paquet, S.; Calatayud, P.-A.; Obonyo, J.; Kaiser, L.; Mougel, F.
10.1101/2021.12.13.472356 — evolutionary biology — Posted on 2022-05-10
3011 Riparian forest restoration as sources of biodiversity and ecosystem functions in anthropogenic landscapes
Antonini, Y.; Beirao, M. V.; Costa, F. V.; Azevedo, C. S.; Wojakowski, M.; Kozovits, A.; Pires, M. R. S.; Sousa, H. C.; Messias, M. C. T. B.; Fujaco, M. A. G.; Leite, M. G. P.; Martins, J. P. V.; Monteiro, G. F.; Dirzo, R.
10.1101/2021.09.08.459375 — ecology — Posted on 2022-05-10
3015 Chromosomal position of ribosomal protein genes impacts long term evolution of Vibrio cholerae.
Larotonda, L. I.; Mornico, D.; Khanna, V.; Bernal-Bayard, J.; Ghigo, J.-M.; Kennedy-Val, M.-E.; Comerci, D. J.; Mazel, D.; Soler-Bistue, A.
10.1101/2022.05.06.490600 — microbiology — Posted on 2022-05-10
3019 Cell-type specific transcriptomics reveals roles for root hairs and endodermal barriers in interaction with beneficial rhizobacterium
Verbon, E. H.; Liberman, L. M.; Zhou, J.; Yin, J.; Pieterse, C. M.; Benfey, P. N.; Stringlis, I. A.; de Jonge, R.
10.1101/2022.05.09.491085 — plant biology — Posted on 2022-05-10
3020 Beyond pathologist-level annotation of large-scale cancer histology for semantic segmentation using immunofluorescence restaining
Komura, D.; Onoyama, T.; Shinbo, K.; Odaka, H.; Hayakawa, M.; Ochi, M.; Herdiantoputri, R.; Sakamoto, K.; Katoh, H.; Ikeda, T.; Ushiku, T.; Ishikawa, S.
10.1101/2022.05.09.489968 — pathology — Posted on 2022-05-10
3022 High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer
Salcher, S.; Sturm, G.; Horvath, L.; Untergasser, G.; Fotakis, G.; Panizzolo, E.; Martowicz, A.; Pall, G.; Gamerith, G.; Sykora, M.; Augustin, F.; Schmitz, K.; Finotello, F.; Rieder, D.; Sopper, S.; Wolf, D.; Pircher, A.; Trajanoski, Z.
10.1101/2022.05.09.491204 — cancer biology — Posted on 2022-05-10
3024 CPSF3 inhibition blocks pancreatic cancer cell proliferation through disruption of core histone processing
Alahmari, A. A.; Chaubey, A. H.; Tisdale, A. A.; Schwarz, C. D.; Cornwell, A. C.; Maraszek, K. E.; Paterson, E. J.; Kim, M.; Venkat, S.; Cortes Gomez, E.; Wang, J.; Gurova, K. V.; Feigin, M. E.
10.1101/2022.05.09.491230 — cancer biology — Posted on 2022-05-10
3025 Trapped pore waters in the open proton channel HV1
Boytsov, D.; Brescia, S.; Chaves, G.; Hannesschlaeger, C.; Siligan, C.; Goessweiner-Mohr, N.; Musset, B.; Pohl, P.
10.1101/2022.05.09.491141 — biophysics — Posted on 2022-05-10
3030 MRI Guided Fresh Tissue Procurement in Radical Prostatectomy Specimens: An Evolutionary Paradigm
Freidlin, R. Z.; Garmendia, M. A.; Krynitsky, J.; Bastian, C.; Schultz, C.; Custer, J.; Young, S.; Mehralivand, S.; Merino, M. J.; Valera, V. A.; Pinto, P.; Turkbey, B.; Choyke, P. L.; Pohida, T. J.
10.1101/2022.05.09.491189 — bioengineering — Posted on 2022-05-10
3031 Spatiotemporal atlas of the fetal brain depicts cortical developmental gradient in Chinese population
Xu, X.; Sun, C.; Sun, J.; Shi, W.; Shen, Y.; Zhao, R.; Luo, W.; Li, M.; Wang, G.; Wu, D.
10.1101/2022.05.09.491258 — bioengineering — Posted on 2022-05-10
3033 Secreted cytokines provide local immune tolerance for human stem cell-derived islets
Gerace, D.; Zhou, Q.; Kenty, J. H.-R.; Sintov, E.; Wang, X.; Boulanger, K. R.; Li, H.; Melton, D.
10.1101/2022.05.09.487072 — bioengineering — Posted on 2022-05-10
3039 Fin ray branching is defined by TRAP+ osteolytic tubules
Cardeira-da-Silva, J.; Bensimon-Brito, A.; Tarasco, M.; Brandao, A. S.; Rosa, J.; Almeida, P. J.; Jacinto, A.; Cancela, M. L.; Gavaia, P. J.; Stainier, D. Y. R.; Laize, V.
10.1101/2022.05.09.491182 — developmental biology — Posted on 2022-05-10
3040 Functional substitutions of amino acids that differ between GDF11 and GDF8 impact skeletal development and skeletal muscle.
Lian, J.; Walker, R. G.; D'Amico, A.; Vujic, A.; Mills, M. J.; Messemer, K. A.; Mendello, K. R.; Goldstein, J. M.; Leacock, K. A.; Epp, S.; Stimpfl, E. V.; Thompson, T. B.; Wagers, A. J.; Lee, R.
10.1101/2022.05.09.491247 — developmental biology — Posted on 2022-05-10
3041 ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1
Bardwell, A. J.; Wu, B.; Sarin, K. Y.; Waterman, M. L.; Atwood, S. X.; Bardwell, L.
10.1101/2021.12.22.473898 — cell biology — Posted on 2022-05-10
3043 A histone deacetylase network regulates epigenetic reprogramming and viral silencing in HIV infected cells
Peterson, J. J.; Lewis, C. A.; Burgos, S. D.; Manickam, A.; Xu, Y.; Clutton, G.; Rowley, A. A.; Richardson, B.; Zou, F.; Simon, J. M.; Margolis, D. M.; Goonetilleke, N.; Browne, E. P.
10.1101/2022.05.09.491199 — molecular biology — Posted on 2022-05-10
3044 A novel rRNA hybridization-based approach to rapid, accurate Candida identification directly from blood culture
Matzko, M. E.; Sephton-Clark, P. C. S.; Young, E. L.; Jhaveri, T. A.; Martinsen, M. A.; Mojica, E.; Boykin, R.; Pierce, V. M.; Cuomo, C. A.; Bhattacharyya, R. P.
10.1101/2022.05.09.491195 — microbiology — Posted on 2022-05-10
3045 Adenovirus-Vectored SARS-CoV-2 Vaccine Expressing S1-N Fusion Protein
Khan, M. S.; Kim, E.; McPherson, A.; Weisel, F. J.; Huang, S.; Kenniston, T. W.; Percivalle, E.; Gambotto, A.; Baldanti, F.; Meisel, M.
10.1101/2022.05.09.491179 — immunology — Posted on 2022-05-10
3046 Lyme Disease IgG N-linked Glycans Contrast the Canonical Inflammatory Signature
Haslund-Gourley, B. S.; Grauzam, S.; Mehta, A. S.; Wigdahl, B.; Comunale, M. A.
10.1101/2022.05.09.491121 — immunology — Posted on 2022-05-10
3047 Peptide Avidity for TCR on CD4 Effectors Determines the Extent of Memory Generation
Jones, M. C.; Castonguay, C.; Nanaware, P. P.; Weaver, G. C.; Stadinski, B.; Kugler-Umana, O. A.; Huseby, E.; Stern, L. J.; Devarajan, P. J.; Swain, S. L.
10.1101/2022.05.09.491158 — immunology — Posted on 2022-05-10
3048 Quantifying dynamic facial expressions under naturalistic conditions
Jeganathan, J.; Campbell, M.; Hyett, M.; Parker, G.; Breakspear, M.
10.1101/2022.05.08.490793 — neuroscience — Posted on 2022-05-10
3050 Application of rapid invisible frequency tagging for brain computer interfaces
Brickwedde, M.; Bezsudnova, Y.; Kowalczyk, A.; Jensen, O.; Zhigalov, A.
10.1101/2022.05.09.491156 — neuroscience — Posted on 2022-05-10
3051 Netrin-1 regulates the balance of glutamatergic connectivity in the adult ventral tegmental area
Cline, M. M.; Juarez, B.; Hunker, A. C.; Regiarto, E. G.; Hariadi, B.; Soden, M. E.; Zweifel, L.
10.1101/2022.05.09.491091 — neuroscience — Posted on 2022-05-10
3060 Chromosome-scale assembly of the lablab genome - A model for inclusive orphan crop genomics
Njaci, I.; Waweru, B.; Kamal, N.; Muktar, M. S.; Fisher, D.; Gundlach, H.; Muli, C.; Muthui, L.; Maranga, M.; Kiambi, D.; Maass, B. L.; Emmrich, P. M.; Entfellner, J.-B. D.; Spannagl, M.; Chapman, M. A.; Shorinola, O.; Jones, C. S.
10.1101/2022.05.08.491073 — genomics — Posted on 2022-05-10
3061 The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson's disease data
Leonard, H. L.; Murtadha, R.; Martinez-Carrasco, A.; Muller-Nedebock, A.; Gil-Martinez, A.-L.; Illarionova, A.; Moore, A.; Bustos, B. I.; Jadhav, B.; Huxford, B.; Storm, C.; Towns, C.; Vitale, D.; Chetty, D.; Yu, E.; Jama, F.; Grenn, F. P.; Salazar, G.; Rateau, G.; Iwaki, H.; Elsayed, I.; Foote, I.; van Rensburg, Z. J.; Kim, J. J.; Yuan, J.; Lake, J.; Brolin, K.; Senkevich, K.; Wu, L.; Tan, M. M. X.; Perinan, M. T.; Makarious, M. B.; Ta, M.; Pillay, N. S.; Betancor, O. L.; Reyes-Perez, P. R.; Jerez, P. A.; Saini, P.; al-Ouran, R.; Sivakumar, R.; Real, R.; Reynolds, R. H.; Hu, R.; Abrahams, S.;
10.1101/2022.05.04.490670 — genetics — Posted on 2022-05-10
3062 The endothelial-specific LINC00607 mediates endothelial angiogenic function
Boos, F.; Oo, J. A.; Warwick, T.; Guenther, S.; Izquierdo Ponce, J.; Buchmann, G.; Li, T.; Seredinski, S.; Haydar, S.; Kashefiolasl, S.; Baker, A. H.; Boon, R. A.; Schulz, M. H.; Miller, F. J.; Brandes, R. P.; Leisegang, M. S.
10.1101/2022.05.09.491127 — molecular biology — Posted on 2022-05-10
3063 MPZ-T124M mouse model replicates human axonopathy and suggest alteration in axo-glia communication
Shackleford, G.; Marziali, L. N.; Sasaki, Y.; Weinstock, N. I.; Rossor, A. M.; Silvestri, N.; Wilson, E. R.; Hurley, E.; Kidd, G. J.; Manohar, S. M.; Ding, D.; Salvi, R. J.; Feltri, M. L.; D'Antonio, M.; Wrabetz, L.
10.1101/2022.05.09.491190 — neuroscience — Posted on 2022-05-10
3066 Molecular architecture of the C. elegans centriole
Gönczy, P.; Woglar, A.; Pierron, M.; Schneider, F. Z.; Jha, K.; Busso, C.
10.1101/2022.05.09.491129 — cell biology — Posted on 2022-05-10
3074 Neuroinflammation plays a critical role in cerebral cavernous malformation disease
Lopez-Ramirez, M. A.; Lai, C. C.; Nelsen, B.; Frias-Anaya, E.; Gallego-Gutierrez, H.; Orecchioni, M.; Sun, H.; Mesarwi, O. A.; Ley, K.; Gongol, B.
10.1101/2022.05.09.491214 — neuroscience — Posted on 2022-05-10
3075 The evolution of information transmission in mammalian brain networks
Griffa, A.; Mach, M.; Dedelley, J.; Gutierrez-Barragan, D.; Gozzi, A.; Allali, G.; Grandjean, J.; Van De Ville, D.; Amico, E.
10.1101/2022.05.09.491115 — neuroscience — Posted on 2022-05-10
3076 Persistence of Cajal-Retzius cells in the postnatal hippocampus is required for development of dendritic spines of CA1 pyramidal cells
Glaerum, I. L.; Dunville, K.; Montaldo, N. P.; Kirikae, H.; Nigro, M. J.; Saetrom, P.; Van Loon, B.; Quattrocolo, G.
10.1101/2022.05.09.491146 — neuroscience — Posted on 2022-05-10
3079 Integrative multi-omics analysis reveals molecular subtypes and tumor evolution of synovial sarcoma
Chen, Y.; Su, Y.; Leo, I. R.; Siavelis, I.; Zeng, J.; Cao, X.; Tsagkozis, P.; Hesla, A. C.; Papakonstantinou, A.; Liu, X.; Huang, W.-K.; Ehnman, M.; Johansson, H.; Lin, Y.; Lehtiö, J.; Zhang, Y.; Larsson, O.; Haglund, F.
10.1101/2022.05.09.490894 — cancer biology — Posted on 2022-05-10
3080 A novel ALDH1A1 inhibitor blocks platinum-induced senescence and stemness in ovarian cancer
Muralikrishnan, V.; Fang, F.; Given, T. C.; Podicheti, R.; Chchterbinine, M.; Sriramkumar, S.; O'Hagan, H. M.; Hurley, T. D.; Nephew, K. P.
10.1101/2022.05.09.491218 — cancer biology — Posted on 2022-05-10
3081 Cryo-EM structure of ex vivo fibrils associated with extreme AA amyloidosis prevalence in a cat shelter
Schulte, T.; Chaves-Sanjuan, A.; Mazzini, G.; Speranzini, V.; Lavatelli, F.; Ferri, F.; Palizzotto, C.; Mazza, M.; Milani, P.; Nuvolone, M.; Vogt, A.-C.; Palladini, G.; Merlini, G.; Bolognesi, M.; Ferro, S.; Zini, E.; Ricagno, S.
10.1101/2022.05.09.491126 — biophysics — Posted on 2022-05-09
3082 Liquid-like assembly of VASP drives actin polymerization and bundling
Graham, K. D.; Chandrasekaran, A.; Wang, L.; Ladak, A.; Lafer, E. M.; Rangamani, P.; Stachowiak, J. C.
10.1101/2022.05.09.491236 — biophysics — Posted on 2022-05-10
3087 Identification of Banana heat responsive long non-coding RNAs and their gene expression analysis.
Murthy, V. S.; Murthy, S.; Ramesh, P.; Niranjan, V.; kumar, v.; bharthi, v.; Bhatt, R.; Hunasikatti, L.; K.V, R.
10.1101/2022.05.09.491188 — molecular biology — Posted on 2022-05-09
3088 SIRT3 deficiency decreases oxidative-metabolism capacity but increases lifespan under caloric restriction
Dhillon, R. S.; Qin, Y. A.; van Ginkel, P. R.; Fu, V. X.; Vann, J. M.; Lawton, A.; Green, C. L.; Manchado-Gobatto, F. B.; Gobatto, C. A.; Lamming, D.; Prolla, T. A.; Denu, J. M.
10.1101/2022.05.09.491205 — molecular biology — Posted on 2022-05-10
3090 Soil nitrogen impacts the rhizosphere microbial community owing to microbial hitchhiking
Liu, Z.; Wang, Z.; Xia, Q.; Zhou, Q.; Wu, X.; Kong, W.; Lei, W.; Zeng, J.; Liu, C.; Wang, Y.; Chang, W.; Li, Z.; Yang, Y.; Yang, L.; Tan, X.
10.1101/2022.05.09.491057 — microbiology — Posted on 2022-05-10
3091 SARS-CoV-2 Spike N-Terminal Domain modulates TMPRSS2-dependent viral entry and fusogenicity
Meng, B.; Datir, R.; Choi, J.; CITIID-NIHR BioResource COVID-19 Collaboration, ; Bradley, J.; Smith, K. G.; Lee, J. H.; Gupta, R. K.
10.1101/2022.05.07.491004 — microbiology — Posted on 2022-05-10
3092 Persistent serum protein signatures define an inflammatory subset of long COVID
Talla, A.; Vasaikar, S. V.; Szeto, G.; Lemos, M. P.; Czartoski, J. L.; MacMillan, H.; Moodie, Z.; Cohen, K. W.; Fleming, L. B.; Thomson, Z.; Okada, L.; Becker, L. A.; Coffey, E. M.; DeRosa, S. C.; Newell, E. W.; Skene, P. J.; Li, X.; Bumol, T. F.; McElrath, M. J.; Torgerson, T. R.
10.1101/2022.05.09.491196 — immunology — Posted on 2022-05-10
3093 Empirical Transmit Field Bias Correction of T1w/T2w Myelin Maps
Glasser, M. F.; Coalson, T. S.; Harms, M. P.; Xu, J.; Baum, G. L.; Autio, J. A.; Auerbach, E. A.; Greve, D. N.; Yacoub, E.; Van Essen, D. C.; Bock, N. A.; Hayashi, T.
10.1101/2021.08.08.455570 — neuroscience — Posted on 2022-05-10
3097 The Drosophila ZAD zinc finger protein Kipferl guides Rhino to piRNA clusters
Brennecke, J.; Baumgartner, L.; Handler, D.; Duchek, P.; Platzer, S.
10.1101/2022.05.09.491178 — genetics — Posted on 2022-05-09
3099 Decoding The Nuclear Genome of The Human Pathogen Babesia duncani Shed Light on its Virulence, Drug Susceptibility and Evolution among Apicomplexa
Lonardi, S.; Singh, P.; Liang, Q.; Vydyam, P.; Khabirova, E.; Fang, T.; Gihaz, S.; Thekkiniath, J.; Munshi, M.; Abel, S.; Batugedara, G.; Gupta, M.; Lu, X. M.; Lenz, T.; Chakravarty, S.; Cornillot, E.; Hu, Y.; Ma, W.; Gonzalez, L. M.; Sanchez, S.; Sanchez-Flores, A.; Estrada, K.; Harb, O. S.; Le Roch, K. G.; Ben Mamoun, C.
10.1101/2022.05.09.491209 — microbiology — Posted on 2022-05-09
3100 Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack
Yang, S.; Hiotis, G.; Wang, Y.; Chen, J.; Wang, J.-h.; Kim, M.; Reinherz, E. L.; Walz, T.
10.1101/2022.05.09.491169 — biophysics — Posted on 2022-05-09
3103 Ubiquitous bacterial polyketides induce cross-kingdom microbial interactions
Krespach, M. K.; Stroe, M. C.; Netzker, T.; Rosin, M.; Zehner, L. M.; Komor, A. J.; Beilmann, J. M.; Krueger, T.; Kniemeyer, O.; Schroeckh, V.; Hertweck, C.; Brakhage, A. A.
10.1101/2022.05.09.491136 — microbiology — Posted on 2022-05-09
3104 Saturated reconstruction of living brain tissue
Velicky, P.; Miguel, E.; Michalska, J. M.; Wei, D.; Lin, Z.; Watson, J. F.; Troidl, J.; Beyer, J.; Ben-Simon, Y.; Sommer, C.; Jahr, W.; Cenameri, A.; Broichhagen, J.; Grant, S. G. N.; Jonas, P.; Novarino, G.; Pfister, H.; Bickel, B.; Danzl, J. G.
10.1101/2022.03.16.484431 — neuroscience — Posted on 2022-05-09
3105 Evolution avoids a pathological stabilizing interaction in the immune protein S100A9
Harman, J. L.; Reardon, P. N.; Costello, S. M.; Warren, G. D.; Phillips, S. R.; Connor, P. J.; Marqusee, S.; Harms, M. J.
10.1101/2022.05.09.490804 — biophysics — Posted on 2022-05-09
3111 Roughening instability of growing 3D bacterial colonies
Martinez-Calvo, A.; Bhattacharjee, T.; Bay, R. K.; Luu, H. N.; Hancock, A. M.; Wingreen, N. S.; Datta, S. S.
10.1101/2022.05.09.491177 — biophysics — Posted on 2022-05-09
3113 Thermal endurance by a hot-spring-dwelling phylogenetic relative of the mesophilic Paracoccus
Mondal, N.; Roy, C.; Chatterjee, S.; Sarkar, J.; Dutta, S.; Bhattacharya, S.; Chakraborty, R.; Ghosh, W.
10.1101/2022.05.08.491110 — microbiology — Posted on 2022-05-09
3116 Centrosome Amplification promotes cell invasion via cell-cell contact disruption and Rap-1 activation
Bourke, E.; Prakash, A.; Paunikar, S.; Webber, M.; McDermott, E.; Vellanki, S. H.; Thompson, K.; Dockery, P.; Jahns, H.; Brown, J. A. L.; Hopkins, A. M.
10.1101/2022.05.09.490051 — cell biology — Posted on 2022-05-09
3119 Prenatal inflammation perturbs fetal hematopoietic development and causes persistent changes to postnatal immunity
Apostol, A. C.; Lopez, D. A.; Lebish, E. J.; Valencia, C. H.; Romero-Mulero, M. C.; Pavlovich, P.; Hernandez, G. E.; Forsberg, E. C.; Cabezas-Wallscheid, N.; Beaudin, A. E.
10.1101/2022.05.08.491095 — cell biology — Posted on 2022-05-09
3120 Visinity: Visual Spatial Neighborhood Analysis for Multiplexed Tissue Imaging Data
Warchol, S.; Krueger, R.; Nirmal, A. J.; Gaglia, G.; Jessup, J.; Ritch, C. C.; Hoffer, J.; Muhlich, J. L.; Burger, M.; Jacks, T. L.; Santagata, S.; Sorger, P. K.; Pfister, H.
10.1101/2022.05.09.490039 — cell biology — Posted on 2022-05-09
3121 Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain
Liu, T.; Stephan, T.; Chen, P.; Chen, J.; Riedel, D.; Yang, Z.; Jakobs, S.; Chen, Z.
10.1101/2022.05.09.491019 — cell biology — Posted on 2022-05-09
3123 Scaled-expansion of the membrane associated cytoskeleton requires conserved kinesin adaptors
Glomb, O.; Swaim, G.; LLancao, P. M.; Lovejoy, C.; Sutradhar, S.; Park, J.; Wu, Y.; Hammarlund, M.; Howard, J.; Ferguson, S.; Yogev, S.
10.1101/2022.05.09.491207 — cell biology — Posted on 2022-05-09
3129 Reproducibility of in-vivo electrophysiological measurements in mice
The International Brain Laboratory, ; Banga, K.; Benson, J.; Bonacchi, N.; Bruijns, S. A.; Campbell, R.; Chapuis, G. A.; Churchland, A. K.; Davatolhagh, M. F.; Lee, H. D.; Faulkner, M.; Hu, F.; Hunterberg, J.; Khanal, A.; Krasniak, C.; Meijer, G. T.; Miska, N. J.; Mohammadi, Z.; Noel, J.-P.; Paninski, L.; Pan-Vazquez, A.; Roth, N.; Schartner, M.; Socha, K.; Steinmetz, N. A.; Taheri, M.; Urai, A. E.; Wells, M.; West, S. J.; Whiteway, M. R.; Winter, O.
10.1101/2022.05.09.491042 — neuroscience — Posted on 2022-05-09
3130 The effect of mating complexity on gene drive dynamics
Verma, P.; Reeves, R. G.; Simon, S.; Otto, M.; Gokhale, C. S.
10.1101/2021.09.16.460618 — evolutionary biology — Posted on 2022-05-09
3132 A Scalable Screening of E. coli Strains for Recombinant Protein Expression
Morao, L. G.; Manzine, L. R.; Barra, A. L. C.; Clementino, L. O. D.; Gutierrez, R. F.; Wrenger, C.; Nascimento, A. S.
10.1101/2021.03.09.434560 — molecular biology — Posted on 2022-05-09
3134 Catheterized bladder environment induces Candida albicans hyphal formation and promotes colonization and persistence through Als1.
La Bella, A. A.; Andersen, M. J.; Gervais, N.; Molina, J. J.; Molesan, A.; Stuckey, P. V.; Wensing, L.; Shapiro, R. S.; Santiago-Tirado, F. H.; Flores-Mireles, A. L.
10.1101/2021.06.01.446547 — microbiology — Posted on 2022-05-09
3135 Reproducibility of in-vivo electrophysiological measurements in mice
The International Brain Laboratory, ; Banga, K.; Benson, J.; Bonacchi, N.; Bruijns, S. A.; Campbell, R.; Chapuis, G. A.; Churchland, A. K.; Davatolhagh, M. F.; Lee, H. D.; Faulkner, M.; Steinmetz, N. A.; Paninski, L.; Taheri, M.; Roth, N.
10.1101/2022.05.09.491042 — neuroscience — Posted on 2022-05-09
3140 Single-Cell RNAseq Analysis Reveals Robust Anti-PD-1-Mediated Increase of Immune Infiltrate in Metastatic Castration-Sensitive Prostate Cancer
Hawley, J. E.; Obradovic, A. Z.; Dallos, M. C.; Lim, E. A.; Runcie, K.; Ager, C. R.; McKiernan, J. M.; Anderson, C. B.; Decastro, G. J.; Weintraub, J. L.; Virk, R. K.; Lowy, I.; Hu, J.; Chaimowitz, M. G.; Guo, X. V.; Zhang, Y.; Worley, J.; Stein, M. N.; Califano, A.; Drake, C. G.
10.1101/2022.05.06.490968 — cancer biology — Posted on 2022-05-09
3141 Single-molecule architecture and heterogeneity of human telomeric DNA and chromatin
Dubocanin, D.; Sedeno Cortes, A.; Ranchalis, J. E.; Real, T.; Mallory, B.; Stergachis, A.
10.1101/2022.05.09.491186 — genomics — Posted on 2022-05-09
3143 Population genomics provide insights into the global genetic structure of Colletotrichum graminicola, the causal agent of maize anthracnose
Rogerio, F.; Baroncelli, R.; Cuevas-Fernandez, F. B.; Becerra, S.; Crouch, J. A.; Bettiol, W.; Azcarate-Peril, M. A.; Malapi-Wigh, M.; Ortega, V.; Betran, J.; Tenuta, A.; Dambolena, J. S.; Esker, P.; Revilla, P.; Jackson-Ziems, T.; Hiltbrunner, J.; Munkvold, G.; Buhinicek, I.; Vicente-Villardon, J. L.; Sukno, S. A.; Thon, M. R.
10.1101/2022.05.07.490914 — genomics — Posted on 2022-05-09
3145 Climate and ant richness explain the global distribution of ant-plant mutualisms
Luo, Y.; Taylor, A.; Weigelt, P.; Guenard, B.; Economo, E. P.; Nowak, A.; Inderjit, ; Kreft, H.
10.1101/2022.05.07.490958 — ecology — Posted on 2022-05-09
3147 Spontaneously produced lysogenic phages are an important component of the soybean Bradyrhizobium mobilome
Joglekar, P.; Ferrell, B. D.; Jarvis, T.; Haramoto, K.; Place, N.; Dums, J. T.; Polson, S. W.; Wommack, K. E.; Fuhrmann, J. J.
10.1101/2022.05.06.490963 — microbiology — Posted on 2022-05-09
3149 High neutralizing antibody levels against SARS-CoV-2 Omicron after UB-612 booster vaccination
Guirakhoo, F.; Wang, S.; Wang, C. Y.; Kuo, H.-K.; Peng, W.-J.; Liu, H.; Wang, L.; Johnson, M.; Hunt, A.; Hu, M. M.; Monath, T. P.; Rumyantsev, A.; Goldblatt, D.
10.1101/2022.03.18.484436 — immunology — Posted on 2022-05-09
3150 Single-dose AAV-based vaccine induces a high level of neutralizing antibodies against SARS-CoV-2 in rhesus macaques
Tong, D.; Zhang, M.; Yang, Y.; Xia, H.; Tong, H.; Zhang, H.; Zeng, W.; Liu, M.; Wu, Y.; Ma, H.; Hu, X.; Liu, W.; Cai, Y.; Yao, Y.; Yao, Y.; Liu, K.; Shan, S.; Li, Y.; Gao, G.; Guo, W.; Peng, Y.; Chen, S.; Rao, J.; Zhao, J.; Min, J.; Zhu, Q.; Zheng, Y.; Liu, L.; Shan, C.; Zhong, K.; Qiu, Z.; Jin, T.; Chiu, S.; Yuan, Z.; Xue, T.
10.1101/2021.05.19.444881 — immunology — Posted on 2022-05-09
3155 NetAct: a computational platform to construct core transcription factor regulatory networks using gene activity
Su, K.; Katebi, A. R.; Kohar, V. R.; Clauss, B.; Gordin, D.; Qin, Z.; Karuturi, R. K. M.; Li, S.; Lu, M.
10.1101/2022.05.06.487898 — systems biology — Posted on 2022-05-09
3156 Cryo-EM structure of gas vesicles for buoyancy-controlled motility
Huber, S. T.; Terwiel, D.; Evers, W. H.; Maresca, D.; Jakobi, A. J.
10.1101/2022.05.08.489936 — biophysics — Posted on 2022-05-09
3157 MAGNETO: an automated workflow for genome-resolved metagenomics
Churcheward, B.; Millet, M.; Bihouee, A.; Fertin, G.; Chaffron, S.
10.1101/2022.05.06.490992 — bioinformatics — Posted on 2022-05-09
3163 Optical control of CRISPR-Cas editing with cyclically caged guide RNAs
Sun, Y.-J.; Liu, J.; Li, J.-J.; Zhang, Y.; Chen, W.-D.; Cai, W.-Q.; Liu, L.; Tang, X.-J.; Hou, J.; Wang, M.; Cheng, L.
10.1101/2022.03.04.482981 — biochemistry — Posted on 2022-05-09
3164 The role of evolutionary modes for trait-based cascades in mutualistic networks
Bastazini, V. A. G.; Debastiani, V.; Cappelatti, L.; Guimaraes, P.; Pillar, V. D. P.
10.1101/2021.10.05.462726 — ecology — Posted on 2022-05-09
3165 Nanoscale resolution imaging of the whole mouse embryos and larval zebrafish using expansion microscopy
Sim, J.; Park, C. E.; Cho, I.; Min, K.; Eom, M.; Han, S.; Jeon, H.; Cho, H.-J.; Cho, E.-S.; Kumar, A.; Chong, Y.; Kang, J. S.; Piatkevich, K. D.; Jung, E. E.; Kang, D.-S.; Kwon, S.-K.; Kim, J.; Yoon, K.-J.; Lee, J.-S.; Boyden, E. S.; Yoon, Y.-G.; Chang, J.-B.
10.1101/2021.05.18.443629 — neuroscience — Posted on 2022-05-09
3166 Nitrogen palaeo-isoscapes: Changing spatial gradients of faunal δ15N in late Pleistocene and early Holocene Europe
Reade, H.; Tripp, J. A.; Fremondeau, D.; Sayle, K. L.; Higham, T. F.; Street, M.; Stevens, R. E.
10.1101/2022.05.05.490797 — paleontology — Posted on 2022-05-09
3168 A Chitin-Binding Protein Ultra-highly expressed in the Outer Fold of Mantle is Related to Shell Colour in Pacific Oyster Crassostrea gigas
Li, M.; Tang, J.; Huang, B.; Liu, Y.; Wei, L.; Han, Y.; Wang, X.; Sang, X.; Yuan, M.; Fan, N.; Cai, S.; Zheng, Y.; Zhang, M.; Wang, X.
10.1101/2022.04.18.488701 — physiology — Posted on 2022-05-08
3171 Biomechanical property of limbal niche maintains stemness through YAP
Bhattacharya, S.; Mukherjee, A.; Pisano, S.; Dimri, S.; Knaane, E.; Altshuler, A.; Nasser, W.; Dey, S.; Shi, L.; Mizrahi, I.; Jokel, O.; Amitai-Lange, A.; Kaganovsky, A.; Mimouni, M.; Socea, S.; Hasson, P.; Feral, C.; Wolfenson, H.; Shalom-Feuerstein, R.
10.1101/2021.05.25.445490 — cell biology — Posted on 2022-05-08
3172 Microbiota responses to different prebiotics are conserved within individuals and associated with habitual fiber intake
Holmes, Z. C.; Villa, M. M.; Durand, H. K.; Jiang, S.; Dallow, E. P.; Petrone, B. L.; Silverman, J. D.; Lin, P.-H.; David, L. A.
10.1101/2021.06.26.450023 — microbiology — Posted on 2022-05-08
3174 Characteristics and Impact of the rNST GABA Network on Neural and Behavioral Taste Responses
Travers, S.; Balasubramanian, K.; Breza, J.; Houser, G.; Klimovich, C.; Travers, J.
10.1101/2022.05.08.491089 — neuroscience — Posted on 2022-05-08
3175 Intracortical remodelling increases in highly-loaded bone after exercise cessation
da Silva, R. G. C.; Sun, T. C.; Mishra, A. P.; Boyde, A.; Doube, M.; Riggs, C. M.
10.1101/2022.05.06.490923 — physiology — Posted on 2022-05-08
3176 Spatial cumulant models enable spatially informed treatment strategies and analysis of local interactions in cancer systems
Hamis, S.; Somervuo, P.; Agren, J. A.; Tadele, D. S.; Kesseli, J.; Scott, J. G.; Nykter, M.; Gerlee, P.; Finkelshtein, D.; Ovaskainen, O.
10.1101/2022.05.07.491050 — cancer biology — Posted on 2022-05-08
3181 Specific binding of Hsp27 and phosphorylated Tau mitigates abnormal Tau aggregation-induced pathology
Zhang, S.; Zhu, Y.; Lu, J.; Liu, z.; Lobato, A. G.; Liu, J.; Qiang, J.; Zeng, W.; Zhang, Y.; Liu, C.; He, Z.; zhai, G.; Li, D.
10.1101/2022.05.08.491088 — biochemistry — Posted on 2022-05-08
3183 Human variation impacting MCOLN2 restricts Salmonella Typhi replication by magnesium deprivation
Gibbs, K. D.; Wang, L.; Anderson, C. E.; Bourgeois, J. S.; Cao, Y.; Gaggioli, M. R.; Puertollano, R.; Ko, D. C.
10.1101/2022.05.08.491078 — genetics — Posted on 2022-05-08
3189 Responses of Agricultural plants to Lithium pollution: Trends, Meta-Analysis, and Perspectives
Shakoor, N.; Adeel, M.; Azeem, I.; Ahmad, M. A.; Zain, M.; Abbas, A.; Zhou, P.; Li, Y.; Ming, X.; Yukui, R.
10.1101/2022.05.07.491047 — plant biology — Posted on 2022-05-08
3191 Adipokine C1q/Tumor necrosis factor-related protein 3 (CTRP3) Attenuates Intestinal Inflammation via Histone Deacetylase Sirtuin 1 (SIRT1)/NF-κB Signaling
Yu, H.; Zhang, Z.; Li, G.; Feng, Y.; Xian, L.; Bakhsh, F. J.; Xu, D.; Xu, C.; Vong, T.; Wu, B.; Selaru, F. M.; Wan, F.; Wong, G. W.; Donowitz, M.
10.1101/2022.05.08.491034 — pathology — Posted on 2022-05-08
3192 Cardiac patch treatment alleviates ischemic cardiomyopathy correlated with reverting Piezo1/2 expression by unloading left ventricular myocardium
Zhu, Y.; Lu, Y.; Jiang, S.; Shen, T.; He, C.; Gao, Y.; Shen, L.; Jin, Q.; Zhao, Y.; Hu, H.; Ling, J.; He, J.; Zhuang, L.
10.1101/2022.05.08.490841 — pathology — Posted on 2022-05-08
3193 AA-amyloidosis in cats (Felis catus) housed in shelters
Ferri, F.; Ferro, S.; Porporato, F.; Callegari, C.; Guglielmetti, C.; Mazza, M.; Ferrero, M.; Crino, C.; Gallo, E.; Drigo, M.; Coppola, L. M.; Gerardi, G.; Schulte, T. P.; Ricagno, S.; Vogel, M.; Storni, F.; Bachmann, M.; Vogt, A.-C.; Caminito, S.; Mazzini, G.; Lavatelli, F.; Palladini, G.; Merlini, G.; Zini, E.
10.1101/2022.05.04.490646 — pathology — Posted on 2022-05-08
3199 Simultaneous and sequential multi-species coronavirus vaccination
Peng, L.; Fang, Z.; Renauer, P. A.; McNamara, A.; Park, J. J.; Lin, Q.; Zhou, X.; Dong, M. B.; Zhu, B.; Zhao, H.; Wilen, C. B.; Chen, S.
10.1101/2022.05.07.491038 — immunology — Posted on 2022-05-08
3203 FIB-SEM analysis on three-dimensional structures of growing organelles in wild Chlorella pyrenoidosa cells
Feng, L.; Guo, W.; Guo, J.; Zhang, X.; zou, x.; rao, m.; Ye, J.; Kuang, C.; Chen, G.; chen, c.; Qin, S.; Yang, W.; cheng, j.
10.1101/2022.05.08.491059 — cell biology — Posted on 2022-05-08
3216 The DC1 domain protein BINUCLEATE POLLEN is required for pollen development in Arabidopsis thaliana
Arias, L. A.; D'Ippolito, S.; Frik, J.; Amigo, N.; Casalongue, C. A.; Pagnussat, G. C.; Fiol, D. F.
10.1101/2022.03.17.484815 — plant biology — Posted on 2022-05-08
3217 Polycystin promotes renal fibrosis through EZH2
Wu, M.; Wang, Y.; Jing, Y.; Chen, D.; Lin, J.; Yuan, M.; Tan, B.; Huang, D.; Ye, C.
10.1101/2021.11.03.467035 — molecular biology — Posted on 2022-05-08
3218 Temporally integrated transcriptome analysis reveals ASFV pathology and host response dynamics
Lin, L.; Zhang, T.; Zhang, Y.; Ahsan, M. A.; Zhao, X.; Shen, Z.; Chen, T.; Shen, N.
10.1101/2022.05.06.490987 — microbiology — Posted on 2022-05-08
3219 Reconstruction of the cell pseudo-space from single-cell RNA sequencing data with scSpace
Liao, J.; Qian, J.; Liu, Z.; Chi, Y.; Zheng, Y.; Shao, X.; Cheng, J.; Cui, Y.; Guo, W.; Yang, P.; Hu, Y.; Bao, H.; Chen, Q.; Li, M.; Zhang, B.; Fan, X.
10.1101/2022.05.07.491043 — bioinformatics — Posted on 2022-05-08
3220 Nitric oxide-induced tyrosine nitration of TrkB impairs BDNF signaling and restrains neuronal plasticity
Biojone, C.; Casarotto, P.; Cannarozzo, C.; Fred, S. M.; Herrera-Rodriguez, R.; Lesnikova, A.; Voipio, M.; Castren, E.
10.1101/2022.05.07.491033 — neuroscience — Posted on 2022-05-08
3221 Multi-tasking Deep Network for Tinnitus Classification and Severity Prediction from Multimodal Structural Images
Lin, C.-T.; Ghosh, S.; Hinkley, L. B.; Dale, C. L.; Souza, A. C.; Sabes, J. H.; Hess, C. P.; Adams, M. E.; Cheung, S. W.; Nagarajan, S.
10.1101/2022.05.07.491000 — neuroscience — Posted on 2022-05-08
3226 A detailed landscape of genomic alterations in malignant peripheral nerve sheath tumor cell lines challenges the current MPNST diagnosis
Magallon-Lorenz, M.; Terribas, E.; Fernandez, M. A.; Requena, G.; Rosas, I.; Mazuelas, H.; Uriarte, I.; Negro, A.; Castellanos, E.; Blanco, I.; DeVries, G.; Kawashima, H.; Legius, E.; Brems, H.; Mautner, V.; Kluwe, L.; Ratner, N.; Wallace, M. R.; Fernandez-Rodriguez, J.; Lazaro, C.; Fletcher, J.; Reuss, D.; Carrio, M.; Gel, B.; Serra, E.
10.1101/2022.05.07.491026 — genomics — Posted on 2022-05-08
3235 Defining the HIV Capsid Binding Site of Nucleoporin 153
Li, S.; Patel, J. S.; Yang, J.; Crabtree, A.; Rubenstein, B. M.; Lund-Andersen, P.; Ytreberg, F. M.; Rowley, P. A.
10.1101/2022.05.06.490988 — molecular biology — Posted on 2022-05-07
3237 Exploring the utility of recombinantly expressed snake venom serine protease toxins as immunogens for generating experimental snakebite antivenoms
Alomran, N.; Blundell, P.; Alsolaiss, J.; Crittenden, E.; Ainsworth, S.; Dawson, C. A.; Edge, R. J.; Hall, S. R.; Harrison, R. A.; Wilkinson, M. C.; Menzies, S. K.; Casewell, N. R.
10.1101/2022.05.07.491032 — immunology — Posted on 2022-05-08
3242 Oxytocin attenuates microglial activation and restores social and non-social memory in the APP/PS1 mouse model of Alzheimer's disease
Selles, M. C.; Fortuna, J. T. S.; de Faria, Y. P. R.; Longo, B. M.; Froemke, R.; Chao, M. V.; Ferreira, S. T.
10.1101/2022.05.07.491031 — neuroscience — Posted on 2022-05-08
3246 Single-cell RNA sequencing reveals molecular features of postnatal maturation in the murine retinal pigment epithelium
PANDEY, R. S.; Krebs, M. P.; Bolisetty, M. T.; Charette, J. R.; Naggert, J. K.; Robson, P.; Nishina, P.; Carter, G. W.
10.1101/2022.05.07.491046 — systems biology — Posted on 2022-05-08
3256 Inhibition of Aromatase by Hops, Licorice Species, and their bioactive compounds in Postmenopausal Breast Tissue
Hajirahimkhan, A.; Howell, C. E.; Chen, S.-N.; Clare, S.; Pauli, G.; Khan, S.; Bolton, J. L.; Dietz, B. M.
10.1101/2022.05.06.490985 — pharmacology and toxicology — Posted on 2022-05-08
3258 Climate and ant richness explain the global distribution of ant-plant mutualisms
Luo, Y.; Taylor, A.; Weigelt, P.; Guénard, B.; Economo, E. P.; Nowak, A.; Inderjit, I.; Kreft, H.
10.1101/2022.05.07.490958 — ecology — Posted on 2022-05-08
3264 A Standardized Ontology for Naming tRNA-derived RNAs Based on Molecular Origin
Holmes, A. D.; Chan, P. P.; Chen, Q.; Ivanov, P.; Drouard, L.; Polacek, N.; Kay, M. A.; Lowe, T. M.
10.1101/2022.05.06.490965 — bioinformatics — Posted on 2022-05-08
3266 Chemical structures of cyclic ADP ribose (cADPR) isomers and the molecular basis of their production and signaling
Manik, M. K.; Shi, Y.; Li, S.; Zaydman, M. A.; Damaraju, N.; Eastman, S.; Smith, T.; Gu, W.; Masic, V.; Mosaiab, T.; Weagley, J. S.; Hancock, S. J.; Vasquez, E.; Hartley-Tassell, L.; Maruta, N.; Lim, B. Y.; Burdett, H.; Lansdberg, M. J.; Schembri, M. A.; Prokes, I.; Song, L.; Grant, M.; DiAntonio, A.; Nanson, J. D.; Guo, M.; Milbrandt, J.; Ve, T.; Kobe, B.
10.1101/2022.05.07.491051 — biochemistry — Posted on 2022-05-08
3268 Stem Cell Secretome Promotes Scarless Corneal Wound Healing and Rescues Corneal Sensory Nerves
Kumar, A.; Li, Y.; Mallick, S.; Yang, E.; Dhaliwal, D. K.; Price, A.; Xie, T.; Du, Y.
10.1101/2022.05.07.490347 — cell biology — Posted on 2022-05-07
3270 A comprehensive list of the replication promoters of Bunyavirales reveals a unique promoter structure in Nairoviridae differing from other virus families
Neriya, Y.; Kojima, S.; Sakiyama, A.; Kishimoto, M.; Iketani, T.; Watanabe, T.; Abe, Y.; Shimoda, H.; Nakagawa, K.; Koma, T.; Matsumoto, Y.
10.1101/2022.05.06.490981 — microbiology — Posted on 2022-05-07
3271 Highly specialized carbohydrate metabolism capability in Bifidobacterium strain associated with intestinal barrier maturation in early preterm infants
Ma, B.; Sundararajan, S.; Nadimpalli, G.; France, M. T.; McComb, E. J.; Rutt, L.; Lemme Dumit, J. M.; Janofsky, E.; Roskes, L.; Gajer, P.; Fu, L.; Yang, H.; Humphrys, M.; Tallon, L. J.; Sadzewicz, L.; Pasetti, M. F.; Ravel, J.; Viscardi, R.
10.1101/2022.05.06.490995 — microbiology — Posted on 2022-05-07
3272 Conservation of energetic pathways for electroautotrophy in the uncultivated candidate order Tenderiales
Eddie, B. J.; Bird, L.; Pelikan, C.; Mussmann, M.; Martinez-Perez, C.; Pinamang, P.; Malanoski, A.; Glaven, S.
10.1101/2022.05.06.490989 — microbiology — Posted on 2022-05-07
3273 Temporally integrated transcriptome analysis reveals ASFV pathology and host response dynamics
Lin, L.; Zhang, T.; Zhang, Y.; Ahsan, M. A.; Zhao, X.; Shen, Z.; Chen, T.; Shen, N.
10.1101/2022.05.06.490987 — microbiology — Posted on 2022-05-07
3275 NetAct: a computational platform to construct core transcription factor regulatory networks using gene activity
Su, K.; Katebi, A. R.; Kohar, V. R.; Clauss, B.; Gordin, D.; Qin, Z.; Karuturi, R. K. M.; Li, S.; Lu, M.
10.1101/2022.05.06.487898 — systems biology — Posted on 2022-05-07
3277 Comparative genomic and crystal structure analyses identify a collagen glucosyltransferase from Acanthamoeba Polyphaga Mimivirus
Wu, W.; Kim, J. S.; Richards, S. J.; Buhlheller, C.; Bailey, A. O.; Russell, W.; Chen, T.; Chen, T.; Chen, Z.; Liang, B.; Yamauchi, M.; Guo, H.
10.1101/2022.05.07.491030 — biochemistry — Posted on 2022-05-07
3280 Comparative and longitudinal analysis of axial and retinal biometry in prospective models of hyperopia
Pinkney, J.; Gogna, N.; Collin, G. B.; Stone, L.; Krebs, M. P.; Naggert, J. K.; Nishina, P.
10.1101/2022.05.07.491049 — genetics — Posted on 2022-05-07
3285 On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis
Key, F. M.; Khadka, V. D.; Romo-Gonzalez, C.; Blake, K. J.; Deng, L.; Lynn, T. C.; Lee, J. C. M.; Chiu, I.; Garcia, M. T.; Lieberman, T. D.
10.1101/2021.03.24.436824 — microbiology — Posted on 2022-05-07
3287 Sleep is required for odor exposure to consolidate memory and remodel olfactory synapses
Chandra, R.; Farah, F.; Munoz-Lobato, F.; Bokka, A.; Benedetti, K. L.; Brueggemann, C.; Saifuddin, F. M.; Miller, J. M.; Li, J.; Chang, E.; Varshney, A.; Jiminez, V.; Baradwaj, A.; Nassif, C.; Alladin, S.; Andersen, K. E.; Bi, V.; Nordquist, S. K.; Dunn, R. L.; Tsujimoto, B.; Tran, A.; Duong, A.; Paisner, R.; Zuazo, C. E.; Churgin, M.; Fang-Yen, C.; Bremer, M.; Kato, S.; L'Etoile, N. D.; VanHoven, M.
10.1101/2020.11.24.395228 — neuroscience — Posted on 2022-05-07
3289 3D Reconstructions of Mouse Skeletal Muscle Reveal a Decrease in the MICOS Complex and Altered Mitochondrial Networks
Vue, Z.; Lopez, E. G.; Neikirk, K.; Vang, L.; Beasley, H.; Shao, J.; Marshall, A.; Crabtree, A.; Evans, C.; Taylor, B.; Christensen, T. A.; Lam, J.; Rodriguez, B.; Dal, J.; Shao, B.; Phillips, M. A.; Davis, J.; Reddy, A. K.; Quintana, A. M.; Murray, S. A.; Exil, V.; Mobley, B.; Gomez, J. A.; Dai, D.-F.; Hinton, A.
10.1101/2022.03.22.485341 — biophysics — Posted on 2022-05-07
3292 Remote contextual fear retrieval engages activity from salience network regions in rats
dos Santos Correa, M.; Grisanti, G. D. V.; Franciscatto, I. A. F.; Tarumoto, T. S. A.; Tiba, P. A.; Ferreira, T. L.; Fornari, R. V.
10.1101/2021.12.22.473939 — neuroscience — Posted on 2022-05-07
3294 A weakly structured stem for human origins in Africa
Ragsdale, A. P.; Weaver, T. D.; Atkinson, E. G.; Hoal, E.; Moller, M.; Henn, B. M.; Gravel, S.
10.1101/2022.03.23.485528 — genomics — Posted on 2022-05-07
3297 Protrusion growth driven by myosin-generated force
Fitz, G. N.; Weck, M. L.; Bodnya, C.; Perkins, O. L.; Tyska, M. J.
10.1101/2022.05.06.490961 — cell biology — Posted on 2022-05-07
3300 Assessing and enhancing foldability in designed proteins
Listov, D.; Lipsh-Sokolik, R.; Rosset, S.; Yang, C.; Correia, B. E.; Fleishman, S. J.
10.1101/2021.11.09.467863 — biochemistry — Posted on 2022-05-07
3301 A synthetic tear protein resolves dry eye through promoting corneal nerve regeneration.
Efraim, Y.; Chen, F. Y. T.; Cheong, K. N.; Gaylord, E. A.; McNamara, N. A.; Knox, S. M.
10.1101/2022.05.07.491018 — cell biology — Posted on 2022-05-07
3302 Evolution and development of male-specific leg brushes in Drosophilidae
Tanaka, K.; Barmina, O.; Thompson, A.; Massey, J. H.; Kim, B. Y.; Suvorov, A.; Kopp, A.
10.1101/786764 — evolutionary biology — Posted on 2022-05-07
3303 Asymmetrical dose-responses shape the evolutionary trade-off between antifungal resistance and nutrient use
Despres, P. C.; Cisneros Caballero, A. F.; Alexander, E. M.; Sonigara, R.; Gagne-Thivierge, C.; Dube, A. K.; Landry, C. R.
10.1101/2021.11.29.469899 — evolutionary biology — Posted on 2022-05-07
3305 Chronic Glucocorticoid Stress Reveals Increased Energy Expenditure and Accelerated Aging as Cellular Features of Allostatic Load
Bobba-Alves, N.; Sturm, G.; Lin, J.; Ware, S. A.; Karan, K. R.; Monzel, A. S.; Bris, C.; Procaccio, V.; Lenaers, G.; Higgins-Chen, A.; Levine, M.; Horvath, S.; Santhanam, B. S.; Kaufman, B. A.; Hirano, M.; Epel, E. S.; Picard, M.
10.1101/2022.02.22.481548 — cell biology — Posted on 2022-05-07
3306 Centriole growth is not limited by a finite pool of components, but is limited by the Cdk1/Cyclin-dependent phosphorylation of Ana2/STIL
Steinacker, T. L.; Wong, S.-S.; Novak, Z. A.; Saurya, S.; Gartenmann, L.; van Houtum, E. J. H.; Sayers, J. R.; Lagerholm, B. C.; Raff, J. W.
10.1101/2022.02.15.480489 — cell biology — Posted on 2022-05-07
3309 Replicative Instability Drives Cancer Progression
Morris, B. B.; Smith, J. P.; Zhang, Q.; Jiang, Z.; Hampton, O. A.; Churchman, M. L.; Arnold, S. M.; Owen, D. H.; Gray, J. E.; Dillon, P. M.; Soliman, H. H.; Stover, D. G.; Colman, H.; Chakravarti, A.; Shain, K. H.; Silva, A. S.; Villano, J. L.; Vogelbaum, M. A.; Borges, V. F.; Akerley, W. L.; Gentzler, R. D.; Hall, R. D.; Matsen, C. B.; Ulrich, C. M.; Post, A. R.; Nix, D. A.; Singer, E. A.; Larner, J. M.; Stukenberg, T.; Jones, D. R.; Mayo, M. W.
10.1101/2022.05.06.490945 — cancer biology — Posted on 2022-05-06
3314 3D Reconstructions of Mouse Skeletal Muscle Reveal a Decrease in the MICOS Complex and Altered Mitochondrial Networks
Vue, Z.; Lopez, E. G.; Neikirk, K.; Vang, L.; Beasley, H.; Shao, J.; Marshall, A.; Crabtree, A.; Evans, C.; Taylor, B.; Christensen, T. A.; Lam, J.; Rodriguez, B.; Dal, J.; Shao, B.; Phillips, M. A.; Davis, J.; Reddy, A. K.; Quintana, A. M.; Murray, S. A.; Exil, V.; Mobley, B.; Gomez, J. A.; Dai, D.-F.; Hinton, A.
10.1101/2022.03.22.485341 — biophysics — Posted on 2022-05-06
3316 Morphogen Directed Coordination of GPCR Activity Promotes Primary Cilium Function for Downstream Signaling
Ansari, S. S.; Dillard, M. E.; Zhang, Y.; Austria, M. A.; Boatwright, N.; Shelton, E. L.; Johnson, A.; Young, B. M.; Rankovic, Z.; Robinson, C. G.; Schuetz, J. D.; Ogden, S. K.
10.1101/2022.05.06.490951 — cell biology — Posted on 2022-05-06
3317 Modulation of Tau Tubulin Kinases (TTBK1 and TTBK2) Impacts Ciliogenesis
Potjewyd, F. M.; Marquez, A. B.; Chaikuad, A.; Howell, S.; Dunn, A. S.; Beltran, A. A.; Smith, J. L.; Drewry, D. H.; Beltran, A. S.; Axtman, A. D.
10.1101/2022.05.06.490937 — cell biology — Posted on 2022-05-06
3318 Developmental Morphogens Direct Human Induced Pluripotent Stem Cells Towards an Annulus Fibrosus-like Cell Phenotype
Peredo, A. P.; Tsinman, T. K.; Bonnevie, E. D.; Jiang, X.; Smith, H. E.; Gullbrand, S. E.; Dyment, N. A.; Mauck, R. L.
10.1101/2022.05.06.490483 — cell biology — Posted on 2022-05-06
3321 The peptide GOLVEN10 controls nodule and lateral root organogenesis and positioning along the longitudinal root axis
Roy, S.; Torres-jerez, I.; Zhang, S.; Liu, W.; Schiessl, K.; Boschiero, C.; Hee-kyung, L.; Zhao, P.; Murray, J.; Oldroyd, G.; Scheible, W.-R.; Udvardi, M.
10.1101/2022.05.06.490929 — plant biology — Posted on 2022-05-06
3322 Metagenomic analysis of coprolites from three Late Pleistocene megaherbivores from the Southwestern United States.
Prys-Jones, T. O.; Furstenau, T. N.; Abraham, A. J.; Shaffer, I. N.; Sobek, C. J.; Upton, J. R.; Hershauer, S. N.; Wong, K.; Molina, M.; Menke, S.; Mead, J. I.; Ebert, C. H.; Carbone, M. S.; Schuur, E. A.; Walker, F. M.; Fofanov, V. Y.; Doughty, C. E.
10.1101/2022.05.06.490351 — paleontology — Posted on 2022-05-06
3325 Messenger-RNA Modification Standards and Machine Learning Models Facilitate Absolute Site-Specific Pseudouridine Quantification
Makhamreh, A.; Tavakoli, S.; Gamper, H.; Nabizadehmashhadtoroghi, M.; Fallahi, A.; Hou, Y.-M.; Rouhanifard, S. H.; Wanunu, M.
10.1101/2022.05.06.490948 — genomics — Posted on 2022-05-06
3326 Early-life nutrition interacts with developmental genes to shape the brain and sleep behavior in Drosophila melanogaster
Olivares, G. H.; Nunez, F.; Candia, N.; Orostica, K.; Vega-Macaya, F.; Zuniga, N.; Molina, C.; Mackay, T. F. C.; Verdugo, R.; Olguin, P.
10.1101/2020.06.28.175356 — genetics — Posted on 2022-05-06
3327 Synovial fibroblasts assume distinct functional identities and secrete R-spondin 2 to drive osteoarthritis
Knights, A. J.; Farrell, E. C.; Ellis, O. M.; Lammlin, L.; Junginger, L. M.; Rzeczycki, P. M.; Bergman, R. F.; Pervez, R.; Cruz, M.; Samani, A. A.; Wu, C.-L.; Hankenson, K. D.; Maerz, T.
10.1101/2022.05.06.489035 — cell biology — Posted on 2022-05-06
3331 Genome graphs detect human polymorphisms in active epigenomic states during influenza infection
Groza, C.; Chen, X.; Pacis, A.; Simon, M.-M.; Pramatarova, A.; Aracena, K. A.; Pastinen, T.; Barreiro, L. B.; Bourque, G.
10.1101/2021.09.29.462206 — bioinformatics — Posted on 2022-05-06
3332 Structure of C. elegans TMC-1 complex illuminates auditory mechanosensory transduction
Jeong, H.; Clark, S.; Goehring, A.; Dehghani-Ghahnaviyeh, S.; Rasouli, A.; Tajkhorshid, E.; Gouaux, E.
10.1101/2022.05.06.490478 — biochemistry — Posted on 2022-05-06
3335 Chromosomal position of ribosomal protein genes impacts long term evolution of Vibrio cholerae.
Larotonda, L. I.; Mornico, D.; Khanna, V.; Bernal-Bayard, J.; Ghigo, J. M.; Kennedy-Val, M.-E.; Comerci, D. J.; Mazel, D.; SOLER-BISTUE, A.
10.1101/2022.05.06.490600 — microbiology — Posted on 2022-05-06
3337 Screening of hydrocarbon-stapled peptides for inhibition of calcium-triggered exocytosis
Lai, Y.; Tuvim, M.; Leitz, J.; Peters, J. J.; Pfuetzner, R.; Esquivies, L.; Zhou, Q.; Czako, B.; Cross, J.; Jones, P.; Dickey, B.; Brunger, A. T.
10.1101/2022.03.21.484632 — pharmacology and toxicology — Posted on 2022-05-06
3338 Ongoing Replication Stress Response and New Clonal T Cell Development Discriminate Between Liver and Lung Recurrence Sites and Patient Outcomes in Pancreatic Ductal Adenocarcinoma
Link, J. M.; Pelz, C.; Worth, P. J.; Owen, S.; Keith, D.; Langer, E. M.; Grossblatt-Wait, A.; Creason, A. L.; Egger, J.; Holly, H.; English, I.; MacPherson, K.; Tsuda, M.; Goecks, J.; Demir, E.; Kardosh, A.; Lopez, C. D.; Sheppard, B. C.; Guimaraes, A.; Brinkerhoff, B.; Morgan, T. K. C.; Mills, G. B.; Brody, J.; Sears, R. C.
10.1101/2022.05.04.490552 — cancer biology — Posted on 2022-05-06
3341 DNA methylation Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic β-cell Heterogeneity
Parveen, N.; Wang, J. K.; Bhattacharya, S.; Cuala, J.; Rajkuman, M. S.; Wu, X.; Shih, H. P.; Georgia, S. K.; Dhawan, S.
10.1101/2022.05.06.490953 — developmental biology — Posted on 2022-05-06
3342 SARS-CoV-2 evolution and patient immunological history shape the breadth and potency of antibody-mediated immunity
Manali, M.; Bissett, L. A.; Amat, J.; Logan, N.; Scott, S.; Hughes, E.; Harvey, W.; Orton, R.; Thomson, E.; Gunson, R.; Viana, M.; Willett, B.; Murcia, P. R.
10.1101/2022.05.06.490867 — microbiology — Posted on 2022-05-06
3344 Heterologous expression of a lycophyte protein enhances angiosperm seedling vigor
Koh, S. W. H.; Bascom, C.; Berenguer, E.; Ingram, G.; Estelle, M.; Hardtke, C.
10.1101/2022.05.06.490942 — plant biology — Posted on 2022-05-06
3345 Insulin receptors in pancreatic acinar cells contribute to KrasG12D-driven cancer initiation in the context of diet-induced obesity
Zhang, A. M. Y.; Xia, Y. H.; Chu, K. H.; Ruiter, T. J. J.; Yang, J. C. C.; Lin, J. S. H.; Chen, N.; Chhuor, J.; Patil, S.; Cen, H. H.; Rideout, E.; Richard, V. R.; Schaeffer, D. F.; Zahedi, R. P.; Borchers, C. H.; Johnson, J. D.; Kopp, J.
10.1101/2022.05.06.490845 — cancer biology — Posted on 2022-05-06
3346 Interrogating the Precancerous Evolution of Pathway Dysfunction in Lung Squamous Cell Carcinoma Using XTABLE
Roberts, M.; Ogden, J.; Hossain, A. S. M. M.; Kerr, A.; Dive, C.; Beane, J.; Lopez-Garcia, C.
10.1101/2022.05.06.490640 — bioinformatics — Posted on 2022-05-06
3349 GDF15 and ACE2 stratify COVID19 patients according to severity while ACE2 mutations increase infection susceptibility.
Torrens-Mas, M.; Perello-Reus, C. M.; Trias-Ferrer, N.; Ibarguen-Gonzalez, L.; Crespi, C.; Galmes-Panades, A. M.; Navas-Enamorado, C.; Sanchez-Polo, A.; Pierola-Lopetegui, J.; Masmiquel, L.; Socias Crespi, L.; Barcelo, C.; Gonzalez-Freire, M.
10.1101/2022.05.06.490907 — molecular biology — Posted on 2022-05-06
3355 Knockout of mitogen-activated protein kinase 3 causes barley root resistance against Fusarium graminearum.
Basheer, J.; Vadovic, P.; Samajova, O.; Melicher, P.; Komis, G.; Krenek, P.; Kralova, M.; Pechan, T.; Ovecka, M.; Takac, T.; Samaj, J.
10.1101/2022.05.04.490681 — plant biology — Posted on 2022-05-06
3356 Insulin Receptor Loss Impairs Mammary Tumorigenesis in Mice
Podmore, L. M.; Poloz, Y.; Mouaaz, S.; Ennis, M.; Smirnov, P.; Lam, S.; Dowling, R.; Stambolic, V.
10.1101/2022.05.06.490906 — cancer biology — Posted on 2022-05-06
3358 Intracellular connections between basal bodies promote the coordinated behavior of motile cilia
Soh, A. W. J.; Woodhams, L. G.; Junker, A. D.; Enloe, C. M.; Noren, B. E.; Harned, A.; Westlake, C. J.; Narayan, K.; Oakey, J. S.; Bayly, P. V.; Pearson, C. G.
10.1101/2022.05.06.490816 — cell biology — Posted on 2022-05-06
3359 ACE2 nanoparticles prevent cell entry of SARS-CoV-2
Sauvanet, C.; Lemos, M.; Bezault, A.; Rodriguez de Francisco, B.; Chan, M. C.; Hui, K. P.; Ng, K.-c.; Nicholls, J. M.; Volkmann, N.; Hanein, D.
10.1101/2022.05.05.490805 — cell biology — Posted on 2022-05-06
3361 The kidney protects against sepsis by producing systemic uromodulin
LaFavers, K.; Hage, C.; Gaur, V.; Micanovic, R.; Hato, T.; Khan, S.; Winfree, S.; Doshi, S.; Moorthi, R.; Twigg, H.; Wu, X.-R.; Dagher, P.; Srour, E.; El-Achkar, T. M.
10.1101/2021.01.08.425960 — immunology — Posted on 2022-05-06
3362 Single neurons and networks in the claustrum integrate input from widespread cortical sources
Shelton, A. M.; Oliver, D. K.; Grimstvedt, J. S.; Lazarte, I. P.; Kapoor, I.; Swann, J. A.; Ashcroft, C. A.; Williams, S. N.; Conway, N.; Robinson, A.; Kentros, C. G.; Witter, M. P.; Butt, S. J.; Packer, A. M.
10.1101/2022.05.06.490864 — neuroscience — Posted on 2022-05-06
3363 Heart Rate Variability Covaries with Amygdala Functional Connectivity During Voluntary Emotion Regulation
Tupitsa, E.; Egbuniwe, I.; Lloyd, W. K.; Puertollano, M.; Macdonald, B.; Joanknecht, K.; Sakaki, M.; van Reekum, C. M.
10.1101/2022.05.06.490895 — neuroscience — Posted on 2022-05-06
3368 Quantification of hypoxic regions distant from occlusions in cerebral penetrating arteriole trees
Xue, Y.; Georgakopoulou, T.; van der Wijk, A.-E.; Jozsa, T. I.; van Bavel, E.; Payne, S. J.
10.1101/2022.05.06.490869 — bioengineering — Posted on 2022-05-06
3369 Phasing of de novo mutations using a scaled-up multiple amplicon long-read sequencing approach
Holt, G. S.; Batty, L.; Alobaidi, B.; Smith, H.; Oud, M. S.; Ramos, L.; Xavier, M. J.; Veltman, J. A.
10.1101/2022.05.06.490885 — genomics — Posted on 2022-05-06
3370 Vertical gradients in physiological function and resource allocation of white spruce diverge at the northern- and southern-most range extremes
Schmiege, S. C.; Griffin, K. L.; Boelman, N. T.; Vierling, L. A.; Bruner, S. G.; Min, E.; Maguire, A. J.; Jensen, J.; Eitel, J. U. H.
10.1101/2022.05.06.490824 — ecology — Posted on 2022-05-06
3373 Endogenous retroviruses promote prion-like spreading of proteopathic seeds
Liu, S.; Heumueller, S. E.; Hossinger, A.; Mueller, S. A.; Buravlova, O.; Lichtenthaler, S. F.; Denner, P.; Vorberg, I. M.
10.1101/2022.05.06.490866 — neuroscience — Posted on 2022-05-06
3374 A novel mouse model of postpartum depression and the neurobiological effects of fast-acting antidepressant treatments
Garcia-Baos, A.; Ferreres-Alvarez, I.; Gallego-Landin, I.; Puig-Reyne, X.; Castro-Zavala, A.; Valverde, O.; Martin-Sanchez, A.
10.1101/2022.05.06.490916 — neuroscience — Posted on 2022-05-06
3375 Subthalamic beta bursts correlate with dopamine-dependent motor symptoms in 106 Parkinson's patients
Lofredi, R.; Okudzhava, L.; Irmen, F.; Bruecke, C.; Huebl, J.; Krauss, J. K.; Schneider, G.-H.; Faust, K.; Neumann, W.-J.; Kuehn, A. A.
10.1101/2022.05.06.490913 — neuroscience — Posted on 2022-05-06
3379 Piezo buffers mechanical stress via modulation of intracellular Ca2+ handling in the Drosophila heart
Zechini, L.; Camilleri-Brennan, J.; Walsh, J.; Beaven, R.; Moran, O.; Hartley, P. S.; Diaz, M.; Denholm, B.
10.1101/2022.05.06.490878 — physiology — Posted on 2022-05-06
3381 Sinking a giant: quantitative macroevolutionary comparative methods debunk qualitative assumptions
Fabbri, M.; Navalon, G.; Benson, R. B.; Pol, D.; O'Connor, J.; Bhullar, B.-A. S.; Erickson, G.; Norell, M. A.; Orkney, A.; Lamanna, M. C.; Zouhri, S.; Becker, J.; Dal Sasso, C.; Bindellini, G.; Maganuco, S.; Auditore, M.; Ibrahim, N.
10.1101/2022.05.05.490811 — paleontology — Posted on 2022-05-06
3382 Nanoscale prognosis of colorectal cancer metastasis from AFM image processing of histological sections
Sarantopoulou, E.; Gavriil, V.; Ferraro, A.; Cefalas, A.-C.; Kollia, Z.; Pepe, F.; Malapelle, U.; De Luca, C.; Troncone, G.
10.1101/2022.05.06.490873 — cancer biology — Posted on 2022-05-06
3383 A glutamine-based single α-helix scaffold to target globular proteins
Escobedo, A.; Piccirillo, J. G.; Aranda, J.; Diercks, T.; Topal, B.; Biesaga, M.; Staby, L.; Kragelund, B. B.; Garcia, J.; Millet, O.; Orozco, M.; Coles, M.; Crehuet, R.; Salvatella, X.
10.1101/2022.05.06.490931 — biophysics — Posted on 2022-05-06
3385 Fluorescence fluctuation based super resolution microscopy, basic concepts for an easy start.
Alva, A.; Brito-Alarcon, E.; Linares, A.; Torres-Garcia, E.; Hernandez, H. O.; Pinto-Camara, R.; Martinez, D.; Hernandez-Herrera, P.; D'Antuono, R.; Wood, C.; Guerrero, A.
10.1101/2022.05.06.490863 — bioinformatics — Posted on 2022-05-06
3386 The Evolution of Protein Folds by Creative Destruction
Alvarez-Carreno, C.; Gupta, R. J.; Petrov, A. S.; Williams, L. D.
10.1101/2022.03.30.486258 — evolutionary biology — Posted on 2022-05-06
3388 A new microbiological weapon against lepidopteran pests
Martemyanov, V.; Akhanaev, Y. B.; Belousova, I. A.; Pavlushin, S. V.; Yakimova, M. E.; Kharlamova, D. D.; Ageev, A. A.; Golovina, A. N.; Astapenko, S. A.; Kolosov, A. V.; Ananko, G. G.; Taranov, O. S.; Shvalov, A. N.; Bodnev, S. A.; Ershov, N. I.; Grushevaya, I. V.; Tymofeev, M. A.; Tokarev, Y. S.
10.1101/2022.05.06.490868 — microbiology — Posted on 2022-05-06
3390 Orai3 and Orai1 are essential for CRAC channel function and metabolic reprogramming in B cells
Emrich, S. M.; Yoast, R. E.; Zhang, X.; Fike, A. J.; Wang, Y.-H.; Bricker, K. N.; Tao, A.; Xin, P.; Walter, V.; Johnson, M. T.; Pathak, T.; Straub, A. C.; Feske, S.; Rahman, Z.; Trebak, M.
10.1101/2022.05.06.490918 — immunology — Posted on 2022-05-06
3392 Compartment-driven imprinting of intestinal CD4 (regulatory) T cells in inflammatory bowel disease and homeostasis
Lutter, L.; ter Linde, J. J. M.; Brand, E. C.; Hoytema van Konijnenburg, D. P.; Roosenboom, B.; Horjus Talabur-Horje, C.; Oldenburg, B.; van Wijk, F.
10.1101/2022.05.06.490870 — immunology — Posted on 2022-05-06
3393 Accelerometer-measured physical activity and cognitive functioning: A Mendelian Randomization study
Cheval, B.; Darrous, L.; Choi, K.; Klimentidis, Y.; Raichlen, D.; Alexander, G.; Cullati, S.; Kutalik, Z.; Boisgontier, M. P.
10.1101/2020.10.16.342675 — neuroscience — Posted on 2022-05-06
3400 Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin
Belyy, A.; Lindemann, F.; Roderer, D.; Funk, J.; Bardiaux, B.; Protze, J.; Bieling, P.; Oschkinat, H.; Raunser, S.
10.1101/2022.05.06.490871 — biochemistry — Posted on 2022-05-06
3404 Plasmid overlap and evolution between Enterobacterales isolates from bloodstream infections and non-human compartments
Matlock, W.; Lipworth, S.; Chau, K. K.; AbuOun, M.; Barker, L.; Kavanagh, J.; Andersson, M.; Oakley, S.; Morgan, M.; Crook, D. W.; Read, D. S.; Anjum, M.; Shaw, L. P.; Stoesser, N.; REHAB Consortium,
10.1101/2022.05.06.490774 — genomics — Posted on 2022-05-06
3406 Urine-derived exosomes from individuals with IPF carry pro-fibrotic cargo.
Elliot, S.; Catanuto, P.; Pereira-Simon, S.; Xia, X.; Shahzeidi, S.; Roberts, E.; Ludlow, J.; Hamdan, S.; Daunert, S.; Parra, J.; Stone, R.; Pastar, I.; Tomic-Canic, M.; Glassberg, M. K.
10.1101/2022.05.06.490876 — cell biology — Posted on 2022-05-06
3408 Activation of neuronal FLT3 promotes exaggerated sensorial and emotional pain-related behaviors facilitating the transition from acute to chronic pain
Tassou, A.; Thouaye, M.; Gilarbert, D.; Jouvenel, A.; Leyris, J.-P.; Sonrier, C.; Diouloufet, L.; Mechaly, I.; Chentouf, M.; Neiveyans, M.; Pugniere, M.; Martineau, P.; Robert, B.; Capdevila, X.; Valmier, J.; Rivat, C.
10.1101/2021.11.23.469557 — neuroscience — Posted on 2022-05-06
3409 Obesity medication lorcaserin requires brainstem GLP-1 neurons to reduce food intake in mice
Wagner, S.; Brierley, D. I.; Leeson-Payne, A.; Jiang, W.; Chianese, R.; Lam, B. Y.; Dowsett, G.; Cristiano, C.; Lyons, D.; Reimann, F.; Gribble, F. M.; Yeo, G. S. H.; Trapp, S.; Heisler, L.
10.1101/2022.05.06.490598 — neuroscience — Posted on 2022-05-06
3410 SWEET13 transport of sucrose, but not gibberellin, restores male fertility in Arabidopsis sweet13;14
Isoda, R.; Palmai, Z.; Yoshinari, A.; Chen, L.-Q.; Tama, F.; Frommer, W. B.; Nakamura, M.
10.1101/2022.05.05.490848 — plant biology — Posted on 2022-05-06
3411 Genomic patterns of malignant peripheral nerve sheath tumour (MPNST) evolution correlate with clinical outcome and are detectable in cell-free DNA
Cortes-Ciriano, I.; Steele, C. D.; Piculell, K. G.; Al-Ibraheemi, A.; Eulo, V.; Bui, M. M.; Chatzipli, A.; Dickson, B. C.; Borcherding, D. C.; Feber, A.; Galor, A.; Hart, J.; Jones, K. B.; Jordan, J. T.; Kim, R. H.; Lindsay, D.; Miller, C.; Nishida, Y.; Proszek, P.; Serrano, J.; Sundby, R. T.; Szymanski, J. J.; Ullrich, N. J.; Viskochil, D.; Wang, X.; Snuderl, M.; Park, P. J.; Flanagan, A. M.; Hirbe, A. C.; Pillay, N.; Miller, D. T.
10.1101/2022.05.03.490481 — cancer biology — Posted on 2022-05-06
3413 Depth normalization for single-cell genomics count data
Booeshaghi, A. S.; Hallgrimsdottir, I. B.; Galvez-Merchan, A.; Pachter, L.
10.1101/2022.05.06.490859 — bioinformatics — Posted on 2022-05-06
3417 Serine Deamination as a New Acid Resistance Mechanism in Escherichia coli
Wiebe, M. A.; Brannon, J. R.; Steiner, B. D.; Bamidele, A.; Schrimpe-Rutledge, A. C.; Codreanu, S. G.; Sherrod, S. D.; McLean, J.; Hadjifrangiskou, M.
10.1101/2022.05.05.490856 — microbiology — Posted on 2022-05-06
3419 Acinetobacter baumannii and cefiderocol between cidality and adaptability
Stracquadanio, S.; Bonomo, C.; Marino, A.; Bongiorno, D.; Privitera, G. F.; Bivona, D. A.; Mirabile, A.; Bonacci, P. G.; Stefani, S.
10.1101/2022.05.05.490855 — microbiology — Posted on 2022-05-06
3420 Bacterial association with metals enables in vivo tracking of microbiota using magnetic resonance imaging
Donnelly, S. C.; Gelman, N.; Thompson, R. T.; Prato, F. S.; Burton, J. P.; Goldhawk, D. E.
10.1101/2022.05.05.490857 — microbiology — Posted on 2022-05-06
3421 Mapping lesion, structural disconnection, and functional disconnection to symptoms in semantic aphasia
Souter, N. E.; Wang, X.; Thompson, H.; Krieger-Redwood, K.; Halai, A.; Lambon Ralph, M.; Thiebaut de Schotten, M.; Jefferies, E.
10.1101/2021.12.01.470605 — neuroscience — Posted on 2022-05-06
3423 Nav1.1 in mammalian sensory neurons is required for normal motor behaviors
Griffith, T.; Espino, C. M.; Lewis, C. M.; Ortiz, S.; Dalal, M. S.; Wells, K. M.; O'Neil, D. A.; Wilkinson, K. A.
10.1101/2022.05.05.490851 — neuroscience — Posted on 2022-05-06
3424 M2-polarized macrophages control LSC fate by enhancing stemness, homing, immune evasion and metabolic reprogramming
Weinhauser, I.; Pereira-Martins, D.; Almeida, L.; Hilberink, J.; Ortiz, C.; Silveira, D.; Quek, L.; Araujo, C.; Bianco, T.; Lucena-Araujo, A.; Visser, N.; Hogeling, S.; Diepstra, A.; Ammatuna, E.; Huls, G.; Rego, E.; Schuringa, J. J.
10.1101/2022.05.06.489506 — cancer biology — Posted on 2022-05-06
3425 An interactive mass spectrometry atlas of histone posttranslational modifications in T-cell acute leukemia
Provez, L.; Van Puyvelde, B.; Corveleyn, L.; Demeulemeester, N.; Verhelst, S.; Lintermans, B.; Daled, S.; Roels, J.; Clement, L.; Martens, L.; Deforce, D.; Van Vlierberghe, P.; Dhaenens, M.
10.1101/2022.05.05.490796 — cancer biology — Posted on 2022-05-06
3426 Automated systematic evaluation of cryo-EM specimens with SmartScope
Bouvette, J.; Huang, Q.; Riccio, A. A.; Copeland, W. C.; Bartesaghi, A.; Borgnia, M. J.
10.1101/2022.05.05.490801 — biophysics — Posted on 2022-05-06
3427 Systematic benchmarking of all-in-one microbial SNP calling pipelines
Falconer, C.; Cuddihy, T.; Beatson, S.; Paterson, D.; Harris, P.; Forde, B.
10.1101/2022.05.05.487569 — bioinformatics — Posted on 2022-05-06
3432 Antigenic characterization and pandemic risk assessment of North American H1 influenza A viruses circulating in swine
Venkatesh, D.; Anderson, T. K.; Kimble, J. B.; Chang, J.; Lopes, S.; Souza, C. K.; Pekosz, A.; Shaw-Saliba, K.; Rothman, R. E.; Chen, K.-F.; Lewis, N.; Vincent, A. L.
10.1101/2022.05.04.490709 — microbiology — Posted on 2022-05-06
3433 A unique epigenomic landscape defines CD8+ tissue-resident memory T cells
Buquicchio, F. A.; Fonseca, R.; Belk, J. A.; Evrard, M.; Obers, A.; Qi, Y.; Daniel, B.; Yost, K. E.; Satpathy, A. T.; Mackay, L. K.
10.1101/2022.05.04.490680 — immunology — Posted on 2022-05-06
3435 Next generation sequencing analysis of gastric cancer identifies the leukemia inhibitory factor receptor (LIFR) as a driving factor in gastric cancer progression and as a predictor of poor prognosis
Di Giorgio, C.; Marchiano, S.; Marino, E.; Biagioli, M.; Roselli, R.; Bordoni, M.; Bellini, R.; Urbani, G.; Zampella, A.; Distrutti, E.; Donini, A.; Graziosi, L.; Fiorucci, S.
10.1101/2022.05.05.490785 — cancer biology — Posted on 2022-05-06
3436 Semi-automated protocol to quantify and characterize fluorescent, 3D vascular images
Xie, D. F.; Crouzet, C.; Lopresti, K.; Wang, Y.; Robinson, C.; Jones, W.; Muqolli, F.; Pai, A.; Fang, C.; Cribbs, D. H.; Fisher, M.; Choi, B.
10.1101/2022.05.05.490827 — bioengineering — Posted on 2022-05-06
3439 Population Genomics of Stone Age Eurasia
Allentoft, M. E.; Sikora, M.; Refoyo-Martinez, A.; Irving-Pease, E. K.; Fischer, A.; Barrie, W.; Ingason, A.; Stenderup, J.; Sjögren, K.-G.; Pearson, A.; Sousa da Mota, B.; Paulsson, B. S.; Halgren, A. S.; Macleod, R.; Schjellerup Jorkov, M. L.; Demeter, F.; Novosolov, M.; Sorensen, L.; Nielsen, P. O.; Henriksen, R. A.; Vimala, T.; McColl, H.; Margaryan, A.; Ilardo, M.; Vaughn, A.; Mortensen, M. F.; Nielsen, A. B.; Hede, M. U.; Rasmussen, P.; Vinner, L.; Renaud, G.; Stern, A. J.; Trolle Jensen, T. Z.; Johannsen, N. N.; Scorrano, G.; Schroeder, H.; Lysdahl, P.; Ramsoe, A.; Skorobogatov, A.; Sc
10.1101/2022.05.04.490594 — evolutionary biology — Posted on 2022-05-06
3440 Asymmetrical dose-response shape the evolutionary trade-off between antifungal resistance and nutrient use
Despres, P. C.; Cisneros Caballero, A. F.; Alexander, E. M.; Sonigara, R.; Gagne-Thivierge, C.; Dube, A. K.; Landry, C. R.
10.1101/2021.11.29.469899 — evolutionary biology — Posted on 2022-05-06
3441 Bacillus thuringiensis Cry1A toxins divert progenitor cell fate toward enteroendocrine lineage by diminishing cell adhesion with intestinal stem cells
JNEID, R.; LOUDHAIEF, R.; ZUCCHINI-PASCAL, N.; NAWROT-ESPOSITO, M.-P.; FICHANT, A.; ROUSSET, R.; BONIS, M.; OSMAN, D.; GALLET, A.
10.1101/2022.04.13.488147 — cell biology — Posted on 2022-05-06
3442 T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice
Bazioti, V.; La Rose, A. M.; Maassen, S.; Bianchi, F.; de Boer, R.; Guilbaud, E.; Svendsen, A. F.; Groenen, A. G.; Marmolejo-Garza, A.; Koster, M. H.; Kloosterhuis, N. J.; Pranger, A. T.; Langelaar-Makkinje, M.; de Bruin, A.; van de Sluis, B.; Kohan, A. B.; Yvan-Charvet, L.; van den Bogaart, G.; Westerterp, M.
10.1101/2022.04.10.487770 — immunology — Posted on 2022-05-06
3444 Developmental dynamics of the postsynaptic proteome to understand synaptic maturation and dysmaturation
Kaizuka, T.; Suzuki, T.; Kishi, N.; Kilimann, M. W.; Ueyama, T.; Watanabe, M.; Okano, H.; Dohmae, N.; Takumi, T.
10.1101/2022.05.05.490828 — neuroscience — Posted on 2022-05-06
3449 A Chitin-Binding Protein Ultra-highly expressed in the Outer Fold of Mantle is Related to Shell Colour in Pacific Oyster Crassostrea gigas
Li, M.; Tang, J.; Huang, B.; Liu, Y.; Wei, L.; Han, Y.; Wang, X.; Sang, X.; Yuan, M.; Fan, N.; Cai, S.; Zheng, Y.; Zhang, M.; Wang, X.
10.1101/2022.04.18.488701 — physiology — Posted on 2022-05-06
3451 Phenotypic and transcriptomic analyses reveal major differences between apple and pear scab nonhost resistance
VERGNE, E.; CHEVREAU, E.; RAVON, E.; GAILLARD, S.; PELLETIER, S.; BAHUT, M.; PERCHEPIED, L.
10.1101/2021.06.01.446506 — genomics — Posted on 2022-05-06
3455 An individualized causal framework for learning intercellular communicationnetworks that define microenvironments of individual tumors
Chen, X.; Chen, L.; Kurten, C. H. L.; Jabbari, F.; Vujanovic, L.; Ding, Y.; Lu, B.; Lu, K.; Kulkarni, A.; Tabib, T.; Lafyatis, R.; Cooper, G. F.; Ferris, R.; Lu, X.
10.1101/2021.11.11.467838 — cancer biology — Posted on 2022-05-06
3456 Sequence grammar underlying unfolding and phase separation of globular proteins
Ruff, K. M.; Choi, Y. H.; Cox, D.; Ormsby, A. R.; Myung, Y.; Ascher, D. B.; Radford, S. E.; Pappu, R. V.; Hatters, D. M.
10.1101/2021.08.20.457073 — biophysics — Posted on 2022-05-06
3457 Single cell transcriptomics of ferrets reveal a common temporal pattern of progenitors in brain development of gyrencephalic mammals
Bilgic, M.; Wu, Q.; Suetsugu, T.; Tsunekawa, Y.; Sitamukai, A.; Kadota, M.; Nishimura, O.; Kuraku, S.; Matsuzaki, F.
10.1101/2022.05.05.490846 — developmental biology — Posted on 2022-05-06
3460 Expression and functional evaluation of recombinant human ABO blood group antigen cleaving glycoside hydrolases α-N-acetylgalactosaminidase, α-galactosidase, and endo-β-galactosidase produced in Escherichia coli
Toh, W. H.; Kuo, Y.; Hsu, S. K.; Chen, B.; Lee, A. J.; Liaw, E.; Lee, J.; Cheng, A.; Hwa, L.; Hu, K.; Chien, S.; Wong, C.; Chang, K.; Hang, M.; Hong, S.; Su, E.; Clapper, J. C.; Hsu, J.
10.1101/2022.05.04.490255 — biochemistry — Posted on 2022-05-06
3461 Complete sequences of six Major Histocompatibility Complex haplotypes, including all the major MHC class II structures
Houwaart, T.; Scholz, S.; Pollock, N.; Palmer, W. H.; Kichula, K.; Strelow, D.; Le, D. B.; Belick, D.; Lautwein, T.; Wachtmeister, T.; Henrich, B.; Köhrer, K.; Parham, P.; Guethlein, L. A.; Norman, P.; Dilthey, A. T.
10.1101/2022.04.28.489875 — genomics — Posted on 2022-05-06
3462 Recommendations for improving statistical inference in population genomics
Johri, P.; Aquadro, C. F.; Beaumont, M.; Charlesworth, B.; Excoffier, L.; Eyre-Walker, A.; Keightley, P. D.; Lynch, M.; McVean, G.; Payseur, B. A.; Pfeifer, S. P.; Stephan, W.; Jensen, J. D.
10.1101/2021.10.27.466171 — evolutionary biology — Posted on 2022-05-06
3465 The Autophagy Receptor TAX1BP1 (T6BP) is a novel player in antigen presentation by MHC-II molecules.
Pereira, M.; Richetta, C.; Sarango, G.; Kumari, A.; Ghosh, M.; Bertrand, L.; Pionneau, C.; Le Gall, M.; Gregoire, S.; Jeger-Madiot, R.; Rosoy, E.; Subra, F.; Delelis, O.; Faure, M.; Esclatine, A.; Graff-Dubois, S.; Stevanovic, S.; Manoury, B.; Ramirez, B. C.; Moris, A.
10.1101/2021.04.21.440798 — immunology — Posted on 2022-05-06
3466 Embodiment of Supernumerary Robotic Limbs in Virtual Reality
Arai, K.; Saito, H.; Fukuoka, M.; Ueda, S.; Sugimoto, M.; Kitazaki, M.; Inami, M.
10.1101/2022.01.31.478373 — neuroscience — Posted on 2022-05-06
3469 Comparative study between radiofrequency- and muscimol-induced inhibition of cultured networks of cortical neuron
Lemercier, C. E.; Garenne, A.; Poulletier de Gannes, F.; El Khoueiry, C.; Arnaud-Cormos, D.; Leveque, P.; Lagroye, I.; Percherancier, Y.; Lewis, N.
10.1101/2022.05.05.490795 — neuroscience — Posted on 2022-05-05
3471 Nitrogen palaeo-isoscapes: Changing spatial gradients of faunal δ15N in late Pleistocene and early Holocene Europe
Reade, H.; Tripp, J. A.; Fremondeau, D.; Sayle, K. L.; Higham, T. F.; Street, M.; Stevens, R. E.
10.1101/2022.05.05.490797 — biochemistry — Posted on 2022-05-05
3472 Commonality of Odorant Receptor Choice Mechanism Revealed by Analysis of a Highly Represented Odorant Receptor Transgene
Makhlouf, M.; D'Hulst, C.; Omura, M.; Rosa, A.; Mina, R.; Bernal-Garcia, S.; Lempert, E.; Saraiva, L.; Feinstein, P.
10.1101/2022.05.05.489571 — neuroscience — Posted on 2022-05-05
3474 Auxin Plays a Role in the Adaptation of Rice to Anaerobic Germination and Seedling Establishment
Lee, K.-W.; Chen, J. J. W.; Wu, C.-S.; Chang, H.-C.; Chen, H.-Y.; Kuo, H.-H.; Lee, Y.-S.; Chang, Y.-L.; Chang, H.-C.; Shiuea, S.-Y.; Wu, Y.-C.; Ho, Y. C.; Chen, P.-W.
10.1101/2022.05.05.490789 — plant biology — Posted on 2022-05-05
3475 Structure-function relationships in mitochondrial transcriptional condensates
Feric, M.; Sarfallah, A.; Dar, F.; Temiakov, D.; Pappu, R. V.; Misteli, T.
10.1101/2021.12.30.474545 — biophysics — Posted on 2022-05-05
3477 Three-dimensional microenvironment regulates gene expression, function, and tight junction dynamics of iPSC-derived blood-brain barrier microvessels
Linville, R. M.; Sklar, M. B.; Grifno, G. N.; Nerenberg, R. F.; Zhou, J.; Ye, R.; DeStefano, J. G.; Guo, Z.; Jha, R.; Jamieson, J. J.; Zhao, N.; Searson, P. C.
10.1101/2021.08.27.457975 — bioengineering — Posted on 2022-05-05
3478 Structure and mechanism of a novel cytomegaloviral DCAF mediating interferon antagonism
Le-Trilling, V. T. K.; Banchenko, S.; Paydar, D.; Leipe, P. M.; Binting, L.; Lauer, S.; Graziadei, A.; Gotthold, C.; Burger, J.; Bracht, T.; Sitek, B.; Lebbink, R. J.; Malyshkina, A.; Mielke, T.; Rappsilber, J.; Spahn, C. M. T.; Voigt, S.; Trilling, M.; Schwefel, D.
10.1101/2022.05.05.490734 — biochemistry — Posted on 2022-05-05
3479 Promiscuous feeding across multiple honey bee hosts amplifies the vectorial capacity of Varroa destructor
Lamas, Z. S.; Solmaz, S.; Ryabov, E. V.; Mowery, J.; Heerman, M.; Sonenshine, D.; Evans, J. D.; Hawthorne, D. J.
10.1101/2022.05.05.490834 — animal behavior and cognition — Posted on 2022-05-05
3480 Optical mapping compendium of structural variants across global cattle breeds
Talenti, A.; Powell, J.; Wragg, D.; Chepkwony, M.; Fisch, A.; Ferreira, B. R.; Marcadante, M. E. Z.; Santos, I. M.; Ezeasor, C. K.; Obishakin, E. F.; Muhanguzi, D.; Amanyire, W.; Silwamba, I.; Muma, J. B.; Mainda, G.; Kelly, R. F.; Toye, P.; Connelley, T. K.; Prendergast, J.
10.1101/2022.05.05.490773 — genomics — Posted on 2022-05-05
3482 Field margins as substitute habitat for the conservation of birds in agricultural wetlands
Mallet, P.; Bechet, A.; Sirami, C.; Mesleard, F.; Blanchon, T.; Calatayud, F.; Dagonet, T.; Gaget, E.; Leray, C.; Galewski, T.
10.1101/2022.05.05.490780 — ecology — Posted on 2022-05-05
3483 Airway Basal Cells Show Regionally Distinct Potential to Undergo Metaplastic Differentiation
Zhou, Y.; Yang, Y.; Qian, J.; Ge, J.; Sinner, D. I.; Ding, H.; Califano, A.; Cardoso, W. V.
10.1101/2022.05.04.490677 — developmental biology — Posted on 2022-05-05
3485 SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating Hes5
Choi, E.-B.; Vodnala, M.; Saini, P.; Zerbato, M.; Ho, J. J.; Anugula, S.; Wang, J.; Sui, S. H.; Yoon, J.; Inouye, C.; Fong, Y. W.
10.1101/2022.04.25.489402 — cell biology — Posted on 2022-05-05
3489 Non-invasive Fluorescence Imaging of Gut Commensal Bacteria in Live Mice
Apostolos, A.; Chordia, M. D.; Kolli, S. H.; Rutkowski, M. R.; Pires, M. M.
10.1101/2022.05.05.489569 — microbiology — Posted on 2022-05-05
3490 mTORC2 contributes to murine systemic autoimmunity
Zhou, X.; Qi, H.; Li, M.; Li, Y.; Zhu, X.; Amin, S.; Mariam, A.; Diadhiou, C.; Davidson, A.; Zeng, H.
10.1101/2021.03.27.437347 — immunology — Posted on 2022-05-05
3491 Multicomponent Pseudomonas aeruginosa vaccines eliciting Th17 cells and functional antibody responses confer enhanced protection against experimental acute pneumonia in mice
Shaikh, M. O. F.; Schaefers, M. M.; Merakou, C.; DiBlasi, M.; Bonney, S.; Liao, T.; Zurakowski, D.; Kehl, M.; Tabor, D. E.; DiGiandomenico, A.; Priebe, G. P.
10.1101/2022.05.05.490820 — immunology — Posted on 2022-05-05
3493 Inter-scanner brain MRI volumetric biases persist even in a harmonized multi-subject study of multiple sclerosis
Clark, K. A.; O'Donnell, C. M.; Elliott, M. A.; Tauhid, S.; Dewey, B. E.; Chu, R.; Khalil, S.; Nair, G.; Sati, P.; DuVal, A.; Pellegrini, N.; Bar-Or, A.; Markowitz, C.; Schindler, M. K.; Zurawski, J.; Calabresi, P. A.; Reich, D. S.; Bakshi, R.; Shinohara, R. T.; The North American Imaging in Multiple Sclerosis Cooperative,
10.1101/2022.05.05.490645 — neuroscience — Posted on 2022-05-05
3496 Pathophysiology of Dyt1 dystonia is mediated by spinal cord dysfunction
Pocratsky, A. M.; Nascimento, F.; Özyurt, M. G.; White, I. J.; Sullivan, R.; Smith, C. C.; Surana, S.; Beato, M.; Brownstone, R. M.
10.1101/2022.05.05.490750 — neuroscience — Posted on 2022-05-05
3497 TMEM106B is increased in Multiple Sclerosis plaques, and deletion causes accumulation of lipid after demyelination
Shafit-Zagardo, B.; Sidoli, S.; Goldman, J. E.; DuBois, J. C.; Corboy, J. R.; Strittmatter, S. M.; Guzik, H.; Graff, S.; Nagra, R. M.
10.1101/2022.05.05.490697 — neuroscience — Posted on 2022-05-05
3499 The modulation of acute stress on Model-Free and Model-Based reinforcement learning in Gambling Disorder
Wyckmans, F.; Banerjee, N.; Saeremans, M.; Otto, A. R.; Kornreich, C.; Vanderijst, L.; Gruson, D.; Carbone, V.; Bechara, A.; Buchanan, T.; Noel, X.
10.1101/2022.05.05.490735 — neuroscience — Posted on 2022-05-05
3501 Spinal cord extracts from sporadic ALS induce and propagate TDP-43 pathology in cerebral organoids
Tamaki, Y.; Ross, J. P.; Alipour, P.; Catoire, H.; Rochefort, D.; Urushitani, M.; Takahashi, R.; Sonnen, J. A.; Stifani, S.; Dion, P. A.; Rouleau, G. A.
10.1101/2022.05.05.490760 — neuroscience — Posted on 2022-05-05
3502 A connectome-based model of conscious access in monkey cortex
Klatzmann, U.; Froudist-Walsh, S.; Bliss, D. P.; Theodoni, P.; Mejias, J. F.; Niu, M.; Rapan, L.; Palomero-Gallagher, N.; Sergent, C.; Dehaene, S.; Wang, X.-J.
10.1101/2022.02.20.481230 — neuroscience — Posted on 2022-05-05
3505 Dynamic regulation of neural variability during working memory reflects dopamine, functional integration, and decision-making
Garrett, D. D.; Kloosterman, N. A.; Epp, S.; Chopurian, V.; Kosciessa, J. Q.; Waschke, L.; Skowron, A.; Shine, J.; Perry, A.; Salami, A.; Rieckmann, A.; Papenberg, G.; Wahlin, A.; Karalija, N.; Andersson, M.; Ricklund, K.; Lovden, M.; Bäckman, L.; Nyberg, L.; Lindenberger, U.
10.1101/2022.05.05.490687 — neuroscience — Posted on 2022-05-05
3507 A Versatile Enhanced Freeze-Substitution Protocol for Volume Electron Microscopy
Belanger, S.; Berensmann, H.; Baena, V.; Duncan, K.; Meyers, B. C.; Czymmek, K. J.
10.1101/2022.05.05.490767 — plant biology — Posted on 2022-05-05
3508 Lipodystrophy can be uncoupled from detrimental metabolic consequences
Chitraju, C.; Fischer, A. W.; Ambaw, Y. A.; Wang, K.; Yuan, B.; Hui, S. T.; Walther, T. C.; Farese, R.
10.1101/2022.05.05.490833 — physiology — Posted on 2022-05-05
3509 Mouse lemur, a new animal model to investigate cardiac pacemaker activity in primates.
DiFrancesco, M. L.; Davaze, R.; Torre, E.; Mesirca, P.; Marrot, M.; Lautier, C.; Fontes, P.; Cuoq, J.; Fernandez, A.; Lamb, N.; Pifferi, F.; Mestre Frances, N.; Mangoni, M. E.; Torrente, A. G.
10.1101/2021.10.25.465774 — physiology — Posted on 2022-05-05
3511 Interictal Signatures of Human Periventricular Nodular Heterotopia
Frazzini, V.; Whitmarsh, S.; Lehongre, K.; Yger, P.; Lemarechal, J.-D.; Mathon, B.; Adam, C.; Hasboun, D.; Lambrecq, V.; Navarro, V.
10.1101/816173 — pathology — Posted on 2022-05-05
3517 The iron-sulfur cluster is critical for DNA binding by human DNA polymerase ϵ
Lisova, A. E.; Baranovskiy, A. G.; Morstadt, L. M.; Babayeva, N. D.; Stepchenkova, E. I.; Tahirov, T. H.
10.1101/2022.05.05.490830 — biochemistry — Posted on 2022-05-05
3520 Temporal analysis suggests a reciprocal relationship between 3D chromatin structure and transcription
Reed, K. S. M.; Davis, E. S.; Bond, M. L.; Cabrera, A.; Thulson, E.; Quiroga, I. Y.; Cassel, S.; Woolery, K. T.; Hilton, I.; Won, H.; Love, M. I.; Phanstiel, D. H.
10.1101/2022.05.05.490836 — genomics — Posted on 2022-05-05
3528 Failure of digit tip regeneration in the absence of suggests Lmx1b functions disparate from dorsoventral polarity
Castilla-Ibeas, A.; Zdral, S.; Galan, L.; Haro, E.; Allou, L.; Campa, V. M.; Icardo, J. M.; Mundlos, S.; Oberg, K. C.; Ros, M.
10.1101/2022.05.05.490742 — developmental biology — Posted on 2022-05-05
3529 Tbx2 is essential for cochlear inner hair cell development and regeneration
Bi, Z.; Li, X.; Ren, M.; Gu, Y.; Zhu, T.; Li, S.; Wang, G.; Sun, S.; Sun, Y.; Liu, Z.
10.1101/2022.05.05.490782 — developmental biology — Posted on 2022-05-05
3531 Combined Lineage Tracing and scRNA-seq Reveals Unexpected First Heart Field Predominance of Human iPSC Differentiation
Galdos, F. X.; Lee, C.; Lee, S.; Goodyer, W.; Paige, S.; Escobar, G.; Darsha, A.; Beck, A.; Xu, S.; Bak, R. O.; Porteus, M.; Wu, S. M.
10.1101/2021.09.30.462465 — developmental biology — Posted on 2022-05-05
3533 GliaMorph: A modular image analysis toolkit to quantify Müller glial cell morphology
Kugler, E. C.; Bravo, I.; Durmishi, X.; Marcotti, S.; Beqiri, S.; Carrington, A.; Stramer, B. C.; Mattar, P.; MacDonald, R. B.
10.1101/2022.05.05.490765 — developmental biology — Posted on 2022-05-05
3534 The Ndc80-Cdt1-Ska1 complex constitute a minimal processive kinetochore-microtubule coupling unit
Rahi, A.; Chakraborty, M.; Agarwal, S.; Vosberg, K.; Agarwal, S.; Wang, A. Y.; McKenney, R. J.; Varma, D.
10.1101/2022.05.05.490787 — cell biology — Posted on 2022-05-05
3536 Disrupted development and altered hormone signaling in male Padi2/Padi4 double knockout mice
Sams, K. L.; Mukai, C.; Marks, B. A.; Mittal, C.; Demeter, E. A.; Nelissen, S.; Grenier, J. K.; Tate, A. E.; Ahmed, F.; Coonrod, S. A.
10.1101/2022.02.09.479603 — molecular biology — Posted on 2022-05-05
3539 Measurement of Accumulation of Small Molecules into Gram-negative Bacteria
Ongwae, G. M.; Chordia, M. D.; Dalesandro, B. E.; Apostolos, A. J.; Pires, M. M.
10.1101/2022.05.05.489932 — microbiology — Posted on 2022-05-05
3540 Mechanical forces impair antigen discrimination by reducing differences in T cell receptor off-rates
Pettmann, J.; Awada, L.; Rozycki, B.; Huhn, A.; Faour, S.; Kutuzov, M. A.; Limozin, L.; Weikl, T. R.; van der Merwe, P. A.; Robert, P.; Dushek, O.
10.1101/2022.05.05.490751 — immunology — Posted on 2022-05-05
3541 Lymph node-targeted vaccine boosting of TCR-T cell therapy enhances anti-tumor 1 function and eradicates solid tumors
Drakes, D. J.; Abbas, A. M.; Shields, J.; Steinbuck, M. P.; Jakubowski, A.; Seenappa, L. M.; Haqq, C. M.; DeMuth, P. C.
10.1101/2022.05.05.490779 — immunology — Posted on 2022-05-05
3542 STEREOLOGICAL EVALUATION OF TISSUE PRESERVATION AFTERNEUROPROTECTIVE TREATMENTS FOR TRAUMATIC SPINAL CORDINJURY
Reigada, D.; Soto, V.; Gonzalez-Rodriguez, M.; Barreda-Manso, M. A.; Soto, A.; Munoz-Galdeano, T.; Maza, R. M.; Nieto-Diaz, M.
10.1101/2022.05.05.490720 — neuroscience — Posted on 2022-05-05
3544 The ventral striatum contributes to energy balance
Walle, R.; Petitbon, A.; Fois, G. R.; Contini, A.; Ortole, R.; Oummadi, A.; Desmedt-Peyrusse, V.; de Kerchove d'Exaerde, A.; GIROS, B.; Chaouloff, F.; Ferreira, G.; Ducrocq, F.; Georges, F.; Trifilieff, P.
10.1101/2022.05.05.490599 — neuroscience — Posted on 2022-05-05
3545 Hierarchical cue control of drug seeking in the face of cost
Collins, V.; Bornhoft, K. N.; Wolff, A.; Sinha, S.; Saunders, B. T.
10.1101/2022.05.05.490799 — neuroscience — Posted on 2022-05-05
3553 A Self-Healing, Viscoelastic Hydrogel Promotes Healing of Brain Lesions
Hu, Y.; Jia, Y.; Wang, S.; Ma, Y.; Huang, G.; Ding, T.; Feng, D.; Genin, G. M.; Wei, Z.; Xu, F.
10.1101/2022.05.05.490746 — bioengineering — Posted on 2022-05-05
3554 Autonomous untethered microinjectors for gastrointestinal delivery of insulin
Ghosh, A.; Liu, W.; Li, L.; Pahapale, G.; Choi, S. Y.; Xu, L.; Huang, Q.; Selaru, F. M.; Gracias, D.
10.1101/2022.05.05.490821 — bioengineering — Posted on 2022-05-05
3555 Genome-centric analysis of short and long read metagenomes reveals uncharacterized microbiome diversity in Southeast Asians
Emmanuel, J.-S. E.; Chia, M.; Bertrand, D.; Saw, W.-Y.; Ravikrishnan, A.; Low, A.; Ding, Y.; Ng, A.; Tan, L. W. L.; Teo, Y.-Y.; Seedorf, H.; Nagarajan, N.
10.1101/2022.05.05.490740 — genomics — Posted on 2022-05-05
3556 Resetting of H3K4me2 during mammalian parental-to-zygote transition
Xu, J.; Wang, C.; Shi, Y.; Guo, J.; Shi, S.; Yi, S.; Hu, K.; Xu, X.; Wang, Y.; Li, Y.
10.1101/2022.05.05.490401 — genetics — Posted on 2022-05-05
3559 NPC1 confers metabolic flexibility in Triple Negative Breast Cancer
O'Neill, K. I.; Kuo, L.-W.; Williams, M. M.; Lind, H. T.; Crump, L. S.; Hammond, N. G.; Spoelstra, N. S.; Caino, M. C.; Richer, J. K.
10.1101/2022.05.05.490674 — cancer biology — Posted on 2022-05-05
3560 Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer
Mello, A.; Ngodup, T.; Lee, Y.; Donahue, K. L.; Li, J.; Rao, A.; Carpenter, E. S.; Crawford, H. C.; Pasca di Magliano, M.; Lee, K. E.
10.1101/2022.05.05.490771 — cancer biology — Posted on 2022-05-05
3561 Mechanistic target of rapamycin (mTOR) regulates self-sustained quiescence, tumor indolence and late clinical metastasis in a Beclin-1-dependent manner.
Nicco, C.; Thomas, M.; Guillermet-Guibert, J.; Havard, M.; Laurent-Tchenio, F.; Doridot, L.; Dautry, F.; Batteux, F.; Tchenio, T.
10.1101/2022.05.05.490726 — cancer biology — Posted on 2022-05-05
3562 Loss of CD24 promotes radiation- and chemo-resistance by inducing stemness properties associated with a hybrid E/M state in breast cancer cells
Bontemps, I.; Lallemand, C.; Biard, D.; Dechamps, N.; Kortulewski, T.; Bourneuf, E.; Siberchicot, C.; Boussin, F.; Chevillard, S.; Campalans, A.; Lebeau, J.
10.1101/2022.05.05.490732 — cancer biology — Posted on 2022-05-05
3566 The characteristics of high-dark-diversity habitats derived from lidar
Moeslund, J. E.; Clausen, K. K.; Dalby, L.; Floejgaard, C.; Partel, M.; Pfeifer, N.; Hollaus, M.; Brunbjerg, A. K.
10.1101/2022.05.05.490326 — ecology — Posted on 2022-05-05
3567 Temporal and spatial patterns of vertebrate extinctions during the Anthropocene
Pincheira-Donoso, D.; Harvey, L. P.; Guirguis, J.; Goodyear, L. E. B.; Finn, C.; Johnson, J.; Grattarola, F.
10.1101/2022.05.05.490605 — ecology — Posted on 2022-05-05
3569 Net-shaped DNA nanostructure designed for rapid/sensitive detection and potential inhibition of SARS-CoV-2 virus
Chauhan, N.; Xiong, Y.; Ren, S.; Dwivedy, A.; Magazine, N.; Zhou, L.; Lin, X.; Zhang, T.; Cunningham, B. T.; Yao, S.; Huang, W.; Wang, X.
10.1101/2022.05.04.490692 — bioengineering — Posted on 2022-05-05
3571 Senescent Preosteoclast Secretome Promotes Metabolic Syndrome Associated Osteoarthritis through Cyclooxygenase 2
Wan, M.; Su, W.; Liu, G.; Mohajer, B.; Wang, J.; Shen, A.; Zhang, W.; Liu, B.; Guermazi, A.; Gao, P.; Cao, X.; Demehri, S.
10.1101/2022.05.05.490792 — cell biology — Posted on 2022-05-05
3576 Microbial paracetamol degradation involves a high diversity of novel amidase enzyme candidates
Rios-Miguel, A. B.; Smith, G. J.; Cremers, G.; van Alen, T. A.; Jetten, M. S. M.; Op den Camp, H. J. M.; Welte, C. U.
10.1101/2022.05.05.490616 — microbiology — Posted on 2022-05-05
3579 Plasmodium falciparum genetic diversity in coincident human and mosquito hosts
Lapp, Z.; Obala, A. A.; Abel, L.; Rasmussen, D. A.; Sumner, K. M.; Freedman, E.; Taylor, S. M.; Prudhomme-O'Meara, W.
10.1101/2022.05.05.490756 — microbiology — Posted on 2022-05-05
3580 Antigenic characterization and pandemic risk assessment of North American H1 influenza A viruses circulating in swine
Venkatesh, D.; Anderson, T. K.; Kimble, J. B.; Chang, J.; Lopes, S.; Souza, C. K.; Pekosz, A.; Shaw-Saliba, K.; Rothman, R. E.; Chen, K.-F.; Lewis, N.; Vincent, A. L.
10.1101/2022.05.04.490709 — microbiology — Posted on 2022-05-05
3582 Testing the link between isoaspartate and Alzheimer's disease etiology
Wang, J.; Guo, C.; Meng, Z.; Zwan, M. D.; Chen, X.; Seelow, S.; Lundström, S. L.; Rodin, S.; Teunissen, C. E.; Zubarev, R. A.
10.1101/2022.05.03.490418 — neuroscience — Posted on 2022-05-05
3583 Genomic patterns of malignant peripheral nerve sheath tumour (MPNST) evolution correlate with clinical outcome and are detectable in cell-free DNA
Cortes-Ciriano, I.; Steele, C. D.; Piculell, K. G.; Al-Ibraheemi, A.; Eulo, V.; Bui, M. M.; Chatzipli, A.; Dickson, B. C.; Borcherding, D. C.; Feber, A.; Galor, A.; Hart, J.; Jones, K. B.; Jordan, J. T.; Kim, R. H.; Lindsay, D.; Miller, C.; Nishida, Y.; Proszek, P.; Serrano, J.; Sundby, R. T.; Szymanski, J. J.; Ullrich, N. J.; Viskochil, D.; Wang, X.; Snuderl, M.; Park, P. J.; Flanagan, A. M.; Hirbe, A. C.; Pillay, N.; Miller, D. T.
10.1101/2022.05.03.490481 — cancer biology — Posted on 2022-05-05
3585 Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation
Montoya, G.; Mesa, P.; Garcia, S.; de la Puente, L.; Aizpurua, G.; Barbacid, M.; G. Lechuga, M. d. c.; Zarzuela, E.; Santiveri, C.; Sanclemente, M.; Munoz, J.; Campos-Olivas, R.; Martinez-Torrecuadrada, J.; Muesteanu, M.
10.1101/2022.05.04.490607 — biochemistry — Posted on 2022-05-05
3586 The role of dynamic DNA methylation in liver transplant rejection in children
Ningappa, M.; Shao, X.; Ashokkumar, C.; Xu, Q.; Zeevi, A.; Grundberg, E.; Pastinen, T.; Sindhi, R.
10.1101/2022.05.03.489748 — genomics — Posted on 2022-05-05
3591 Structure of the lysosomal membrane fusion machinery
Shvarev, D.; Schoppe, J.; Koenig, C.; Perz, A.; Fuellbrunn, N.; Kiontke, S.; Langemeyer, L.; Januliene, D.; Schnelle, K.; Kuemmel, D.; Froehlich, F.; Moeller, A.; Ungermann, C.
10.1101/2022.05.05.490745 — biophysics — Posted on 2022-05-05
3593 PKD autoinhibition in trans regulates activation loop autophosphorylation in cis
Reinhardt, R.; Hirzel, K.; Link, G.; Eisler, S. A.; Haegele, T.; Parson, M. A. H.; Burke, J. E.; Hausser, A.; Leonard, T. A.
10.1101/2022.05.05.490744 — biochemistry — Posted on 2022-05-05
3597 Microglial expression of the Wnt signalling modulator DKK2 differs between human Alzheimer's disease brains and mouse neurodegeneration models
Aghaizu, N. D.; Jolly, S.; Samra, S. K.; Kalmar, B.; Craessaerts, K.; Greensmith, L.; Salinas, P. C.; De Strooper, B.; Whiting, P. J.
10.1101/2022.05.05.490649 — neuroscience — Posted on 2022-05-05
3598 Biological age is increased by stress and restored upon recovery
Poganik, J. R.; Zhang, B.; Baht, G.; Kerepesi, C.; Yim, S. H.; Lu, A.; Haghani, A.; Gong, T.; Hedman, A.; Andolf, E.; Pershagen, G.; Almqvist, C.; White, J.; Horvath, S.; Gladyshev, V. N.
10.1101/2022.05.04.490686 — systems biology — Posted on 2022-05-05
3600 Groundfish biodiversity change in northeast Pacific waters under projected warming and deoxygenation
Thompson, P. L.; Nephin, J.; Davies, S. C.; Park, A. E.; Lyons, D. A.; Rooper, C. N.; Pena, M. A.; Christian, J. R.; Hunter, K. L.; Rubidge, E.; Holdsworth, A. M.
10.1101/2022.05.04.490690 — ecology — Posted on 2022-05-05
3601 Development of dim-light vision in the nocturnal coral reef fish family, Holocentridae
Fogg, L. G.; Cortesi, F.; Lecchini, D.; Gache, C.; Marshall, N. J.; de Busserolles, F.
10.1101/2022.05.04.490704 — developmental biology — Posted on 2022-05-05
3603 Neural correlates for neonicotinoid-induced impairment of olfactory long-term memory
Cabirol, A.; Calliari, N.; Fayolle, M.; Bariselli, S.; Schloetel, J.-G.; Haase, A.
10.1101/2022.05.04.489639 — neuroscience — Posted on 2022-05-05
3604 Common genetic variants in CHRNA5 alter β-amyloid neuropathology and highlight chandelier cells in human aging and Alzheimer's disease
Rybnicek, J.; Chen, Y.; Milic, M.; McLaurin, J.; De Jager, P.; Schneider, J. A.; Wang, Y.; Bennett, D. A.; Tripathy, S.; Felsky, D.; Lambe, E. K.
10.1101/2022.05.03.490491 — neuroscience — Posted on 2022-05-05
3605 Curation of BIDS (CuBIDS): a workflow and software package for streamlining reproducible curation of large BIDS datasets
Covitz, S.; Tapera, T.; Adebimpe, A.; Alexander-Bloch, A.; Bertolero, M. A.; Feczko, E.; Franco, A. R.; Gur, R. E.; Gur, R. C.; Hendrickson, T.; Houghton, A.; Mehta, K.; Murtha, K.; Perrone, A. J.; Robert-Fitzgerald, T.; Schabdach, J. M.; Shinohara, R. T.; Vogel, J. W.; Zhao, C.; Fair, D. A.; Milham, M. P.; Cieslak, M.; Satterthwaite, T. D.
10.1101/2022.05.04.490620 — neuroscience — Posted on 2022-05-05
3608 Involvement of Lateral Habenula Dysfunction in Repetitive Mild Traumatic Brain Injury-Induced Motivational Deficits
Flerlage, W. J.; Langlois, L. D.; Rusnak, M.; Simmons, S. C.; Gouty, S.; Armstrong, R. C.; Cox, B. M.; Symes, A. J.; Tsuda, M.; Nugent, F. S.
10.1101/2022.05.04.490685 — neuroscience — Posted on 2022-05-05
3614 Development of a Well-Characterized Cynomolgus Macaque Model of Sudan Virus Disease for Support of Product Development
Alfson, K. J.; Goez-Gazi, Y.; Gazi, M.; Chou, Y.-L.; Niemuth, N. A.; Mattix, M. E.; Staples, H.; Klaffke, B.; Rodriguez, G. F.; Escareno, P.; Bartley, C.; Ticer, A.; Clemmons, E. A.; Dutton, J. W.; Griffiths, A.; Meister, G. T.; Sanford, D. C.; Cirimotich, C. M.; Carrion, R.
10.1101/2022.05.04.490569 — microbiology — Posted on 2022-05-05
3616 Polaramycin B, and not physical interaction, is the signal that rewires fungal metabolism in the Streptomyces - Aspergillus interaction.
Berger, H.; Bacher, M.; Labuda, R.; Eppel, I. M.; Bayer, F.; Sulyok, M.; Gasparotto, E.; Doppler, M.; Gratzl, H.; Strauss, J.
10.1101/2022.05.04.490618 — microbiology — Posted on 2022-05-05
3617 BREEDIT: A novel multiplex genome editing strategy to improve complex quantitative traits in maize (Zea mays L.)
Lorenzo, C. D.; Debray, K.; Herwegh, D.; Develtere, W.; Impens, L.; Schaumont, D.; Vandeputte, W.; Aesaert, S.; Coussens, G.; de Boe, Y.; Demuynck, K.; Van Hautegem, T.; Pauwels, L.; Jacobs, T. B.; Ruttink, T.; Nelissen, H.; Inze, D.
10.1101/2022.05.02.490346 — systems biology — Posted on 2022-05-05
3620 A framework for multiplex imaging optimization and reproducible analysis
Eng, J. R.; Bucher, E.; Hu, Z.; Zheng, T.; Gibbs, S.; Chin, K.; Gray, J. W.
10.1101/2021.11.29.470281 — cancer biology — Posted on 2022-05-05
3624 Population Genomics of Stone Age Eurasia
Allentoft, M. E.; Sikora, M.; Refoyo-Martinez, A.; Irving-Pease, E. K.; Fischer, A.; Barrie, W.; Ingason, A.; Stenderup, J.; Sjögren, K.-G.; Pearson, A.; Sousa da Mota, B.; Paulsson, B. S.; Halgren, A. S.; Schjellerup Jorkov, M. L.; Demeter, F.; Novosolov, M.; Macleod, R.; Sorensen, L.; Nielsen, P. O.; Henriksen, R. A.; Vimala, T.; McColl, H.; Margaryan, A.; Ilardo, M.; Vaughn, A.; Mortensen, M. F.; Nielsen, A. B.; Hede, M. U.; Rasmussen, P.; Vinner, L.; Renaud, G.; Stern, A. J.; Trolle Jensen, T. Z.; Johannsen, N. N.; Schroeder, H.; Scorrano, G.; Ramsoe, A.; Skorobogatov, A.; Schork, A. J.;
10.1101/2022.05.04.490594 — evolutionary biology — Posted on 2022-05-05
3627 Accelerated aging induced by stress in experimental murine ocular hypertension.
Xu, Q.; Rydz, C.; Nguyen Huu, V. A.; Rocha, L.; Palomino La Torre, C.; Lee, I.; Cho, W.; Jabari, M.; Donello, J.; Weinreb, R. N.; Lyon, D. C.; Ju, W.-K.; Foik, A.; Skowronska-Krawczyk, D.
10.1101/2022.05.01.490248 — molecular biology — Posted on 2022-05-05
3628 NAD kinase promotes Staphylococcus aureus pathogenesis by supporting production of virulence factors and protective enzymes
Leseigneur, C.; Boucontet, L.; Duchateau, M.; Pizarro-Cerda, J.; Matondo, M.; Colucci-Guyon, E.; Dussurget, O.
10.1101/2021.08.09.455706 — microbiology — Posted on 2022-05-05
3631 Learning of new associations invokes a major change in modulations of cortical beta oscillations in human adults
Pavlova, A.; Tyulenev, N.; Tretyakova, V.; Skavronskaya, V.; Nikolaeva, A.; Prokofyev, A.; Stroganova, T.; Chernyshev, B.
10.1101/2022.05.02.490325 — neuroscience — Posted on 2022-05-05
3632 bi-axial orientation could explain range expansion in a migratory songbird
Wynn, J.; Fandos, G.; Delmore, K.; Van Doren, B.; Fransson, T.; Liedvogel, M.
10.1101/2022.05.04.490589 — zoology — Posted on 2022-05-05
3633 pop-1/TCF, ref-2/ZIC and T-box factors regulate the development of anterior cells in the C. elegans embryo
Rumley, J. D.; Preston, E. A.; Cook, D.; Peng, F. L.; Zacharias, A. L.; Wu, L.; Jileaeva, I.; Murray, J. I.
10.1101/2021.12.14.472681 — genetics — Posted on 2022-05-05
3635 The Colon Mucosal Sialylglycome Is Redox-Regulated by the Golgi Enzyme QSOX1
Ilani, T.; Reznik, N.; Yeshaya, N.; Feldman, T.; Vilela, P.; Lansky, Z.; Javitt, G.; Shemesh, M.; Brenner, O.; Elkis, Y.; Varsano, N.; Murray, N.; Azadi, P.; Jaramillo, A. M.; Evans, C. M.; Fass, D.
10.1101/2022.05.03.490496 — cell biology — Posted on 2022-05-05
3636 Efficient and accurate prime editing strategy to correct genetic alterations in hiPSC using single EF-1alpha driven all-in-one plasmids
Weuring, W. J.; Dirkx, N.; Vriendt, E. D.; Smal, N.; Vondervoort, J. v. d.; Slot, R. v. t.; Koetsier, M.; Weckhuysen, S.; Koeleman, B. P. C.
10.1101/2022.05.04.490422 — molecular biology — Posted on 2022-05-05
3638 The phosphoproteome is a first responder in tiered cellular adaptation to chemical stress followed by proteomics and transcriptomics alteration
Chen, P.; Li, Y.; Xu, F.; Zhang, Z.; Zuo, T.; Guo, J.; Li, K.; Liu, S.; Li, S.; Yin, J.; Chang, L.; Kukic, P.; Liddell, M.; Tulum, L.; Carmichael, P.; Peng, S.; Li, J.; Zhang, Q.; Xu, P.
10.1101/2022.04.07.487458 — pharmacology and toxicology — Posted on 2022-05-05
3639 Discovery and characterization of a first-in-field transcription factor BRN2 inhibitor for the treatment of neuroendocrine prostate cancer.
Thaper, D.; Munuganti, R.; Aguda, A.; Kim, S.; Ku, S.-y.; Sivak, O.; Kumar, S.; Vahid, S.; Ganguli, D.; Beltran, H.; Morrissey, C. M.; Corey, E.; Zoubeidi, A.
10.1101/2022.05.04.490172 — cancer biology — Posted on 2022-05-05
3641 Airway Basal Cells Show Regionally Distinct Potential to Undergo Metaplastic Differentiation
Zhou, Y.; Yang, Y.; Qian, J.; Ge, J.; Sinner, D. I.; Ding, H.; Califano, A.; Cardoso, W. V.
10.1101/2022.05.04.490677 — developmental biology — Posted on 2022-05-05
3642 Contributions and synaptic basis of diverse cortical neuron responses to task performance
Insanally, M. N.; Albanna, B. F.; Toth, J.; DePasquale, B.; Fadaei, S.; Gupta, T.; Kuchibhotla, K.; Rajan, K.; Froemke, R. C.
10.1101/2022.05.04.490676 — neuroscience — Posted on 2022-05-05
3643 A multiplexed assay of human glucokinase reveals thousands of potential disease variants with both decreased and increased activity
Gersing, S.; Cagiada, M.; Gebbia, M.; Gjesing, A. P.; Seesankar, G.; Stein, A.; Gloyn, A. L.; Hansen, T.; Roth, F.; Lindorff-Larsen, K.; Hartmann-Petersen, R.
10.1101/2022.05.04.490571 — genetics — Posted on 2022-05-05
3644 Actin nano-architecture of phagocytic podosomes
Herron, J. C.; Hu, S.; Watanabe, T.; Nogueira, A. T.; Liu, B.; Kern, M.; Arron, J.; Taylor, A.; Pablo, M.; Chew, T.-L.; Elston, T. C.; Hahn, K. M.
10.1101/2022.05.04.490675 — cell biology — Posted on 2022-05-05
3646 Katanin is involved in Microtubule Polymerization into Dendritic Spines and regulates Synaptic Plasticity
Lombino, F. L.; Schwarz, J. R.; Pechmann, Y.; Schweizer, M.; Glatzel, M.; Gee, C. E.; Gromova, K. V.; Kneussel, M.
10.1101/2022.05.04.490623 — neuroscience — Posted on 2022-05-05
3649 Introgression of the Triticum timopheevii genome into wheat detected by chromosome-specific KASP markers
King, J.; Grewal, S.; Othmeni, M.; Coombes, B.; Yang, C.-y.; Walter, N.; Ashling, S.; Scholefield, D.; Walker, J.; Hubbart-Edwards, S.; Hall, A.; King, I.
10.1101/2022.05.04.490655 — plant biology — Posted on 2022-05-05
3651 Hypereosinophilia causes progressive cardiac pathologies in mice
Diny, N. L.; Wood, M. K.; Won, T.; Talor, M. V.; Lukban, C.; Bedja, D.; Wang, N.; Talbot, C. C.; Lin, B. L.; Cihakova, D.
10.1101/2022.05.04.490445 — pathology — Posted on 2022-05-05
3652 Lipid droplets are a metabolic vulnerability in melanoma
Lumaquin, D.; Montal, E.; Baggiolini, A.; Ma, Y.; LaPlante, C.; Huang, T.-H.; Suresh, S.; Studer, L.; White, R. M.
10.1101/2022.05.04.490656 — cancer biology — Posted on 2022-05-05
3653 Human papilloma virus E6 regulates therapy responses in oropharyngeal cancer by repressing the PGC-1α/ERRα axis
Sannigrahi, M. K.; Rajagopalan, P.; Lai, L.; Liu, X.; Sahu, V.; Nakagawa, H.; Jalaly, J. B.; Brody, R. M.; Morgan, I. M.; Windle, B. E.; Wang, X.; Gimotty, P. A.; Kelly, D. P.; White, E. A.; Basu, D.
10.1101/2022.05.04.490169 — cancer biology — Posted on 2022-05-05
3662 Effects of microplastics mixed with natural particles on Daphnia magna populations
Schuer, C.; Beck, J.; Lambert, S.; Scherer, C.; Oehlmann, J.; Wagner, M.
10.1101/2022.05.04.490562 — ecology — Posted on 2022-05-05
3667 Chronic lymphocytic leukemia includes a tumor subset resembling memory B cells that develop early and persist
Budeus, B.; Dampmann, M.; Kibler, A.; Brauser, M.; Bronischewski, K.; Homp, E.; Taudien, S.; Johansson, P.; Bloehdorn, J.; Stilgenbauer, S.; von Tresckow, J.; Reinhardt, H. C.; Küppers, R.; Dürig, J.; Seifert, M.
10.1101/2022.05.04.490383 — immunology — Posted on 2022-05-04
3668 KIF21B binds Myosin Va for Spine Entry and regulates Actin Dynamics to control Homeostatic Synaptic Downscaling
Gromova, K. V.; Thies, E.; Duerst, C. D.; Stajano, D.; Schweizer, M.; Mikhaylova, M.; Gee, C. E.; Kneussel, M.
10.1101/2022.05.04.490582 — neuroscience — Posted on 2022-05-04
3671 A pro-oxidant combination of resveratrol and copper down-regulates multiple biological hallmarks of ageing and neurodegeneration
Pal, K.; Gorantla, R. V.; D'souza, J.; Mehta, S.; Jadhav, V.; Shaikh, A.; Rane, B.; Tandel, H.; Kondhalkar, D.; Chaudhary, S.; Mittra, I.
10.1101/2022.05.04.489500 — neuroscience — Posted on 2022-05-04
3672 Plasma miRNA-214 is a predictive candidate biomarker of progression speed in patients with ALS
Noh, M.-Y.; Kwon, M.-S.; Oh, K.-w.; Nahm, M.; Park, J.; Kim, Y.-E.; Jin, H. K.; Bae, J.-s.; Ki, C.-S.; Kim, S. H.
10.1101/2022.05.04.490596 — neuroscience — Posted on 2022-05-04
3676 Behavioral and brain responses to verbal stimuli reveal transient periods of cognitive integration of external world in all sleep stages
Turker, B.; Munoz Musat, E.; Chabani, E.; Fonteix-Galet, A.; Maranci, J.-B.; Wattiez, N.; Pouget, P.; Sitt, J. D.; Naccache, L.; Arnulf, I.; Oudiette, D.
10.1101/2022.05.04.490484 — neuroscience — Posted on 2022-05-05
3679 A computational toolbox to investigate the metabolic potential and resource allocation in fission yeast
Grigaitis, P.; Grundel, D. A. J.; van Pelt-KleinJan, E.; Isaku, M.; Xie, G.; Mendoza Farias, S.; Teusink, B.; van Heerden, J. H.
10.1101/2022.05.04.490403 — systems biology — Posted on 2022-05-04
3682 Identification of neoantigens in esophageal adenocarcinoma
Nicholas, B.; Bailey, A.; McCann, K. J.; Wood, O.; Walker, R. C.; Parker, R.; Ternette, N.; Elliott, T.; Underwood, T. J.; Johnson, P.; Skipp, P.
10.1101/2022.05.04.490567 — cancer biology — Posted on 2022-05-04
3685 The H2A.Z.1/PWWP2A/NuRD-associated protein HMG20A controls early head and heart developmental transcription programs
Herchenroether, A.; Gossen, S.; Friedrich, T.; Reim, A.; Daus, N.; Diegmueller, F.; Leers, J.; Moghaddas Sani, H.; Gerstner, S.; Schwarz, L.; Stellmacher, I.; Szymkowiak, L. V.; Nist, A.; Stiewe, T.; Borggrefe, T.; Mann, M.; Mackay, J. P.; Bartkuhn, M.; Borchers, A.; Lan, J.; Hake, S. B.
10.1101/2022.05.04.490592 — molecular biology — Posted on 2022-05-04
3686 The Tryptophan Metabolizing Enzyme Indoleamine 2,3-Dioxygenase 1 Regulates Polycystic Kidney Disease Progression
Nguyen, D. T.; Kleczko, E. K.; Dwivedi, N.; Gitomer, B. Y.; Chonchol, M. B.; Clambey, E. T.; Nemenoff, R. A.; Klawitter, J.; Hopp, K.
10.1101/2022.05.04.490641 — molecular biology — Posted on 2022-05-04
3687 A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature
Kemble, A.; Hornsperger, B.; Ruf, I.; Richter, H.; Benz, J.; Kuhn, B.; Heer, D.; Wittwer, M.; Engelhardt, B.; Grether, U.; Collin, L.
10.1101/2022.05.04.490688 — neuroscience — Posted on 2022-05-04
3689 A neural mechanism for terminating decisions
Stine, G. M.; Trautmann, E. M.; Jeurissen, D.; Shadlen, M. N.
10.1101/2022.05.02.490327 — neuroscience — Posted on 2022-05-04
3692 Polio Virotherapy of Malignant Glioma Engages the Tumor Myeloid Infiltrate and Induces Diffuse Microglia Activation
Yang, Y.; Brown, M. C.; Zhang, G.; Stevenson, K.; Mohme, M.; Kornahrens, R.; Bigner, D. D.; Ashley, D. M.; Lopez, G. Y.; Gromeier, M.
10.1101/2022.04.19.488771 — cancer biology — Posted on 2022-05-04
3693 3D Reconstructions of Mouse Skeletal Muscle Reveal a Decrease in the MICOS Complex and Altered Mitochondrial Networks
Vue, Z.; Lopez, E. G.; Neikirk, K.; Vang, L.; Beasley, H.; Shao, J.; Marshall, A.; Crabtree, A.; Evans, C.; Taylor, B.; Christensen, T. A.; Lam, J.; Rodriguez, B.; Phillips, M. A.; Davis, J.; Reddy, A. K.; Quintana, A. M.; Murray, S. A.; Exil, V.; Mobley, B.; Gomez, J. A.; Dai, D.-F.; Hinton, A.
10.1101/2022.03.22.485341 — biophysics — Posted on 2022-05-04
3696 Best practice recommendations for sample preservation in metabarcoding studies: a case study on diatom environmental samples
Baricevic, A.; Chardon, C.; Kahlert, M.; Karjalainen, S. M.; Maric Pfannkuchen, M.; Pfannkuchen, M.; Rimet, F.; Smodlaka Tankovic, M.; Trobajo, R.; Vasselon, V.; Zimmermann, J.; Bouchez, A.
10.1101/2022.05.04.490577 — molecular biology — Posted on 2022-05-04
3697 Spt6 directly interacts with Cdc73 and is required for Paf1C recruitment to active genes
Ellison, M. A.; Blacksmith, M. S.; Namjilsuren, S.; Shirra, M. K.; Schusteff, R. A.; Kerr, E. M.; Fang, F.; Xiang, Y.; Shi, Y.; Arndt, K. M.
10.1101/2022.05.04.490663 — molecular biology — Posted on 2022-05-04
3699 Remote contextual fear retrieval engages activity from salience network regions in rats
dos Santos Correa, M.; Grisanti, G. D. V.; Franciscatto, I. A. F.; Tarumoto, T. S. A.; Tiba, P. A.; Ferreira, T. L.; Fornari, R. V.
10.1101/2021.12.22.473939 — neuroscience — Posted on 2022-05-04
3700 Direct observation of the neural computations underlying a single decision
Steinemann, N. A.; Stine, G. M.; Trautmann, E. M.; Zylberberg, A.; Wolpert, D. M.; Shadlen, M. N.
10.1101/2022.05.02.490321 — neuroscience — Posted on 2022-05-04
3701 Plant biomechanics and resilience to environmental changes are controlled by specific lignin chemistries in each vascular cell type and morphotype
Menard, D.; Blaschek, L.; Kriechbaum, K.; Lee, C. C.; Serk, H.; Zhu, C.; Lyubartsev, A.; Nuoendagula, N.; Bacsik, Z.; Bergström, L.; Mathew, A.; Kajita, S.; Pesquet, E.
10.1101/2021.06.12.447240 — plant biology — Posted on 2022-05-04
3706 Genetic structure correlates with ethnolinguistic diversity in eastern and southern Africa
Atkinson, E. G.; Dalvie, S.; Pichkar, Y.; Kalungi, A.; Majara, L.; Stevenson, A.; Abebe, T.; Akena, D.; Alemayehu, M.; Ashaba, F. K.; Atwoli, L.; Baker, M.; Chibnik, L. B.; Creanza, N.; Daly, M. J.; Fekadu, A.; Gelaye, B.; Gichuru, S.; Injera, W. E.; James, R.; Kariuki, S. M.; Kigen, G.; Koen, N.; Koenen, K. C.; Koenig, Z.; Kwobah, E.; Kyebuzibwa, J.; Musinguzi, H.; Mwema, R. M.; Neale, B. M.; Newman, C. P.; Newton, C. R. J. C.; Ongeri, L.; Ramachandran, S.; Ramesar, R.; Shiferaw, W.; Stein, D. J.; Stroud, R. E.; Teferra, S.; Yohannes, M. T.; Zingela, Z.; Martin, A. R.; NeuroGAP-Psychosis Stud
10.1101/2021.05.19.444732 — genomics — Posted on 2022-05-04
3707 High-throughput single-cell sequencing for retroviral reservoir characterization
Droske, L. E.; Shank, S. D.; Cash, M. N.; Pond, S. L. K.; Salemi, M.; Magalis, B. R.
10.1101/2022.05.04.490630 — genomics — Posted on 2022-05-04
3708 Earliest photic zone niches probed by ancestral microbial rhodopsins
Sephus, C.; Fer, E.; Garcia, A. K.; Adam, Z. R.; Schwieterman, E.; Kacar, B.
10.1101/2021.11.18.469010 — evolutionary biology — Posted on 2022-05-04
3712 Oxytocin promotes epicardial cell activation and heart regeneration after cardiac injury
Wasserman, A. H.; Huang, A. R.; Lewis-Israeli, Y. R.; Dooley, M. D.; Mitchell, A. L.; Venkatesan, M.; Aguirre, A.
10.1101/2021.11.01.466355 — developmental biology — Posted on 2022-05-04
3715 EGFR inhibition leads to enhanced desmosome assembly and cohesion in cardiomyocytes
Shoykhet, M.; Dervishi, O.; Menauer, P.; Hiermaier, M.; Waschke, J.; Yeruva, S.
10.1101/2022.04.27.489705 — cell biology — Posted on 2022-05-04
3717 Polaramycin B, and not physical interaction, is the signal that rewires fungal metabolism in the Streptomyces - Aspergillus interaction.
Berger, H.; Bacher, M.; Labuda, R.; Eppel, I. M.; Bayer, F.; Sulyok, M.; Gasparotto, E.; Doppler, M.; Gratzl, H.; Strauss, J.
10.1101/2022.05.04.490618 — microbiology — Posted on 2022-05-04
3718 The MIX domain is required for T6SS-mediated effector secretion
Fridman, C. M.; Jana, B.; Ben-Yaakov, R.; Bosis, E.; Salomon, D.
10.1101/2022.05.04.489851 — microbiology — Posted on 2022-05-04
3719 Overexpression of UCP4 in astrocytic mitochondria prevents multilevel dysfunctions in a mouse model of Alzheimer s disease
Rosenberg, N.; Reva, M.; Restivo, L.; Briquet, M.; Bernardinelli, Y.; Rocher, A.-B.; Markram, H.; Chatton, J.-Y.
10.1101/2022.01.25.477694 — neuroscience — Posted on 2022-05-04
3720 BrainStat: A toolbox for brain-wide statistics and neuroscientific contextualization
Vos de Wael, R.; Bayrak, S.; Benkarim, O.; Herholz, P.; Lariviere, S.; Rodriguez-Cruces, R.; Paquola, C.; Hong, S.-J.; Misic, B.; Evans, A.; Valk, S.; Bernhardt, B.
10.1101/2022.01.18.476795 — neuroscience — Posted on 2022-05-04
3722 Temporal PHATE: A multi-view manifold learningmethod for brain state trajectories
Busch, E. L.; Huang, J.; Benz, A.; Wallenstein, T.; Lajoie, G.; Wolf, G.; Krishnaswamy, S.; Turk-Browne, N. B.
10.1101/2022.05.03.490534 — neuroscience — Posted on 2022-05-04
3725 LSD and psilocybin flatten the brain's energy landscape: insights from receptor-informed network control theory
Singleton, S. P.; Luppi, A. I.; Carhart-Harris, R. L.; Cruzat, J.; Roseman, L.; Nutt, D. J.; Deco, G.; Kringelbach, M. L.; Stamatakis, E. A.; Kuceyeski, A.
10.1101/2021.05.14.444193 — neuroscience — Posted on 2022-05-04
3727 SERS uncovers the link between conformation of cytochrome c heme and mitochondrial membrane potential
Brazhe, N. A.; Nikelshparg, E. I.; Baizhumanov, A. A.; Grivennikova, V. G.; Semenova, A. A.; Novikov, S. M.; Volkov, V. S.; Arsenin, A. V.; Yakubovsky, D. I.; Evlyukhin, A. B.; Bochkova, Z. V.; Goodilin, E. A.; Maksimov, G. V.; Sosnovtseva, O.; Rubin, A. B.
10.1101/2021.01.03.425119 — biophysics — Posted on 2022-05-04
3731 Three-dimensional envelope and subunit interactions of the plastid-encoded RNA polymerase from Sinapis alba
Ruedas, R.; Coute, Y.; Kieffer-Jaquinod, S.; Sankari Muthukumar, S.; Gillet, F.-X.; Fenel, D.; Effantin, G.; Pfannschmidt, T.; Blanvillain, R.; Cobessi, D.
10.1101/2022.05.04.490580 — biochemistry — Posted on 2022-05-04
3732 Impact of Salmonella genome rearrangement on gene expression
Waters, E. V.; Tucker, L. A.; Ahmed, J. K.; Wain, J.; Langridge, G. C.
10.1101/2022.05.04.490575 — genomics — Posted on 2022-05-04
3738 Efficient and accurate prime editing strategy to correct genetic alterations in hiPSC using single EF-1alpha driven all-in-one plasmids
Weuring, W. J.; Dirkx, N.; Vriendt, E. D.; Smal, N.; Koeleman, B. P. C.; Vondervoort, J. v. d.; Koetsier, M.; Weckhuysen, S.
10.1101/2022.05.04.490422 — molecular biology — Posted on 2022-05-04
3739 Role of High Mobility Group B protein HmbA, orthologue of yeast Nhp6p, in Aspergillus nidulans
Ámon, J.; Varga, G. I.; Pfeiffer, I.; Karácsony, Z.; Hegedüs, Z.; Vágvölgyi, C.; Hamari, Z.
10.1101/2022.05.04.490617 — microbiology — Posted on 2022-05-04
3740 Mapping the T cell repertoire to a complex gut bacterial community
Nagashima, K.; Zhao, A.; Atabakhsh, K.; Weakley, A.; Jain, S.; Meng, X.; Cheng, A.; Wang, M.; Higginbottom, S.; Dimas, A.; Murugkar, P.; Fischbach, M. A.
10.1101/2022.05.04.490632 — immunology — Posted on 2022-05-04
3742 Combination therapy targeting inflammasome and fibrogenesis alleviates inflammation and fibrosis in a zebrafish model of silicosis
Tyrkalska, S. D.; Pedoto, A.; Martinez-Lopez, A.; Candel, S.; Ros-Lucas, J. A.; Mesa-del-Castillo, P.; Mulero, V.
10.1101/2022.05.04.490486 — immunology — Posted on 2022-05-04
3744 Huntingtin turnover: Modulation of huntingtin degradation by cAMP-dependent protein kinase A (PKA) phosphorylation of C-HEAT domain Ser2550
Lee, Y.; Kim, H.; Barker, D.; Vijayvargia, R.; Atwal, R. S.; Specht, H.; Keshishian, H.; Carr, S. A.; Lee, R.; Kwak, S.; Hyun, K.-g.; Loupe, J.; MacDonald, M. E.; Song, J.-J.; Seong, I.
10.1101/2022.05.04.490694 — biochemistry — Posted on 2022-05-04
3746 Cyclic nucleotide-induced superhelical structure activates a bacterial TIR immune effector
Hogrel, G.; Guild, A.; Graham, S.; Rickman, H.; Grushow, S.; Bertrand, Q.; Spagnolo, L.; White, M. F.
10.1101/2022.05.04.490601 — biochemistry — Posted on 2022-05-04
3747 Large-Scale, Multi-Year Microbial Community Survey of a Freshwater Trout Aquaculture Facility
Testerman, T.; Beka, L.; Reichley, S. R.; King, S.; Welch, T. J.; Wiens, G. D.; Graf, J.
10.1101/2022.05.03.490559 — microbiology — Posted on 2022-05-04
3748 Subtyping evaluation of Salmonella Enteritidis using SNP and core genome MLST with nanopore reads
Xian, Z.; Li, S.; Mann, D. A.; Huang, Y.; Xu, F.; Wu, X.; Tang, S.; Zhang, G.; Stevenson, A.; Ge, C.; Deng, X.
10.1101/2022.05.03.490560 — microbiology — Posted on 2022-05-04
3750 The soil microbiome may offer solutions to ginger cultivation
Wang, C.-W.; Michelle Wong, J.-W.; Yeh, S.-S.; Eric Hsieh, Y.; Tseng, C.-H.; Yang, S.-H.; Tang, S.-L.
10.1101/2022.05.03.490558 — microbiology — Posted on 2022-05-04
3751 Hybrid offspring of C57BL/6J mice exhibit improved properties for neurobehavioral research
Sloin, H. E.; Bikovski, L.; Levi, A.; Amber-Vitos, O.; Katz, T.; Spivak, L.; Someck, S.; Gattegno, R.; Sivroni, S.; Sjulson, L.; Stark, E.
10.1101/2022.05.03.490527 — neuroscience — Posted on 2022-05-04
3755 CRISPR metabolic screen identifies ATM and KEAP1 as targetable genetic vulnerabilities in solid tumors.
Li, H.; Liu, Y.; Wilson, C. N.; Bai, H. J.; Jones, M.; Wang, S.; Xiao, Y.; DeVore, J. E.; Maier, E. Y.; Boufraqech, M.; Weyemi, U.
10.1101/2022.05.03.490553 — cancer biology — Posted on 2022-05-04
3756 Mechanics of lung cancer: A finite element model shows strain amplification during early tumorigenesis
Zitnay, R. G.; Herron, M. R.; Carney, K. R.; Potter, S.; Emerson, L. L.; Weiss, J. A.; Mendoza, M. C.
10.1101/2022.05.03.490386 — cancer biology — Posted on 2022-05-04
3761 Trogocytic-molting of T-cell microvilli controls T-cell clonal expansion
Park, J.-S.; Kim, J.-H.; Soh, W.-C.; Lee, K.-S.; Kim, C.-H.; Chung, I.-J.; Lee, S.; Kim, H.-R.; Jun, C.-D.
10.1101/2022.05.03.490404 — immunology — Posted on 2022-05-04
3763 Temporal PHATE: A multi-view manifold learningmethod for brain state trajectories
Busch, E. L.; Huang, J.; Benz, A.; Wallenstein, T.; Lajoie, G.; Wolf, G.; Krishnaswamy, S.; Turk-Browne, N. B.
10.1101/2022.05.03.490534 — neuroscience — Posted on 2022-05-04
3764 HIV integration in the human brain is linked to microglial activation and 3D genome remodeling
Plaza-Jennings, A.; Valada, A.; O'Shea, C.; Iskhakova, M.; Hu, B.; Javidfar, B.; Ben Hutta, G.; Lambert, T.; Murray, J.; Kassim, B.; Chandrasekaran, S.; Chen, B. K.; Morgello, S.; Won, H.; Akbarian, S.
10.1101/2022.05.03.490485 — neuroscience — Posted on 2022-05-04
3765 N-terminal mutant Huntingtin deposition correlates with CAG repeat length and disease onset, but not neuronal loss in Huntington's disease
Layburn, F. E.; Tan, A. Y. S.; Mehrabi, N. F.; Curtis, M. A.; Tippett, L. J.; Riguet, N.; Aeschbach, L.; Lashuel, H. A.; Dragunow, M.; Faull, R. L. M.; Singh-Bains, M. K.
10.1101/2022.05.03.490349 — neuroscience — Posted on 2022-05-04
3766 Within- and between-subject reproducibility and variability in multi-modal, longitudinal brain networks
Nakuci, J.; Wasylyshyn, N.; Cieslak, M.; Elliot, J. C.; Bansal, K.; Giesbrecht, B.; Grafton, S. T.; Vettel, J. M.; Garcia, J. O.; Muldoon, S. F.
10.1101/2022.05.03.490544 — neuroscience — Posted on 2022-05-04
3767 Dog Size and Patterns of Disease History Across the Canine Age Spectrum: Results from the Dog Aging Project
Nam, Y.; White, M.; Karlsson, E. K.; Creevy, K. E.; Promislow, D. E. L.; McClelland, R. L.; The Dog Aging Project Consortium,
10.1101/2022.05.03.490110 — physiology — Posted on 2022-05-04
3768 Iron homeostasis governs erythroid phenotype in Polycythemia Vera
Bennett, C.; Jackson, V. E.; Pettikiriarachchi, A.; Hayman, T.; Schaeper, U.; Moir-Meyer, G.; Fielding, K.; Ataide, R.; Clucas, D.; Baldi, A.; Garnham, A. L.; Li-Wai-Suen, C. S.; Alexander, W. S.; Bahlo, M.; Burbury, K.; Ng, A. P.; Pasricha, S.-R.
10.1101/2022.05.03.490556 — cancer biology — Posted on 2022-05-04
3770 Development of Molecular Inversion Probes for Soybean Progeny Genomic Selection Genotyping
Wang, H.; Campbell, B.; Happ, M.; McConaughy, S.; Lorenz, A. J.; Amundsen, K.; Song, Q.; Pantalone, V.; Hyten, D.
10.1101/2022.05.03.490091 — genomics — Posted on 2022-05-04
3772 Principled Feature Attribution for Unsupervised Gene Expression Analysis
Janizek, J. D.; Spiro, A.; Celik, S.; Blue, B. W.; Russell, J. C.; Lee, T.-I.; Kaeberlin, M.; Lee, S.-I.
10.1101/2022.05.03.490535 — bioinformatics — Posted on 2022-05-04
3776 IPT9, a cis-zeatin cytokinin biosynthesis gene, promotes root growth
Antoniadi, I.; Mateo-Bonmati, E.; Pernisova, M.; Brunoni, F.; Antoniadi, M.; Villalonga, M. G.-A.; Ament, A.; Karady, M.; Turnbull, C.; Dolezal, K.; Pencik, A.; Ljung, K.; Novak, O.
10.1101/2022.05.03.490520 — plant biology — Posted on 2022-05-04
3777 Quantification of cell penetrating peptide mediated delivery of proteins in plant leaves
Wang, J. W.-T.; Goh, N. S.-Y.; Lien, E. S.; Gonzalez-Grandio, E.; Landry, M. P.
10.1101/2022.05.03.490515 — plant biology — Posted on 2022-05-04
3778 Membrane curvature sensing and stabilization by the autophagic LC3 lipidation machinery
Jensen, L. E.; Rao, S.; Schuschnig, M.; Cada, A. K.; Martens, S.; Hummer, G.; Hurley, J. H.
10.1101/2022.05.03.490522 — biophysics — Posted on 2022-05-04
3781 Regulation of astrocyte lipid metabolism and ApoE secretion by the microglial oxysterol, 25-hydroxycholesterol
CASHIKAR, A. G.; Rios, D. T.; Timm, D.; Romero, J.; Long, J.; Han, X.; Holtzman, D.; Paul, S. M.
10.1101/2022.05.03.490494 — cell biology — Posted on 2022-05-04
3782 The Colon Mucosal Sialylglycome Is Redox-Regulated by the Golgi Enzyme QSOX1
Ilani, T.; Reznik, N.; Yeshaya, N.; Feldman, T.; Vilela, P.; Lansky, Z.; Javitt, G.; Shemesh, M.; Brenner, O.; Elkis, Y.; Varsano, N.; Murray, N.; Azadi, P.; Jaramillo, A. M.; Evans, C. M.; Fass, D.
10.1101/2022.05.03.490496 — cell biology — Posted on 2022-05-04
3783 Clemastine fumarate enhances myelination and promotes functional recovery in a syndromic ASD mouse model of Pitt-Hopkins Syndrome
Bohlen, J. F.; Cleary, C. M.; Das, D.; Sripathy, S. R.; Sadowski, N. L.; Shim, G.; Kenney, R. F.; Buchler, I. P.; Mulkey, D. K.; Maher, B. J.
10.1101/2022.05.03.490512 — neuroscience — Posted on 2022-05-04
3784 Single cell transcriptomic profiling of tauopathy in a novel 3D neuron-astrocyte coculture model
Rickner, H. D.; Jiang, L.; Hong, R.; O'Neill, N. K.; Medalla, M.; Zhang, L.; Shaw, D.; Wolozin, B.; Cheng, C. S.
10.1101/2022.05.03.490513 — neuroscience — Posted on 2022-05-04
3786 Regional context for balancing sagebrush- and woodland-dependent songbird needs with targeted pinyon-juniper management in the sagebrush biome
Tack, J. D.; Smith, J. T.; Doherty, K. E.; Donnelly, P. J.; Maestas, J. D.; Allred, B. W.; Reinhardt, J.; Morford, S. L.; Naugle, D. E.
10.1101/2022.05.03.490495 — ecology — Posted on 2022-05-04
3790 Structural snapshots of nitrosoglutathione binding and reactivity underlying S-nitrosylation of photosynthetic GAPDH
Mattioli, E. J.; Rossi, J.; Meloni, M.; De Mia, M.; Marchand, C. H.; Tagliani, A.; Fanti, S.; Falini, G.; Trost, P.; Lemaire, S. D.; Fermani, S.; Calvaresi, M.; Zaffagnini, M.
10.1101/2022.05.03.490436 — plant biology — Posted on 2022-05-04
3791 AI inspired discovery of new biomarkers for clinical prognosis of liver cancer
Liang, J.; Zhang, W.; Yang, J.; Wu, M.; Dai, Q.; Yin, H.; Xiao, Y.; Kong, L.
10.1101/2022.05.03.490448 — cancer biology — Posted on 2022-05-04
3792 Quantum CART (qCART), a piggyBac-based system for development and production of virus-free multiplex CAR-T cell therapy
Chen, Y.-C.; Hua, W.-K.; Hsu, J. C.; Chang, P. S.; Wen, K.-L. K.; Huang, Y.-W.; Tsai, J.-C.; Kao, Y.-H.; Wu, P.-H.; Wang, P.-N.; Chen, K.-F.; Liao, W.-T.; Wu, S. C.-Y.
10.1101/2022.05.03.490469 — cancer biology — Posted on 2022-05-04
3793 Manufacturing highly potent CD20/CD19-targeted iCasp9 regulatable CAR-T cells using the Quantum pBac-based CAR-T (qCART) system for clinical application
Chen, Y.-C.; Chang, P. S.; Hua, W.-K.; Hsu, J. C.; Tsai, J.-C.; Huang, Y.-W.; Kao, Y.-H.; Wu, P.-H.; Chang, Y.-F.; Chang, M. C.; Chang, Y. C.; Wen, K.-L. K.; Wu, S. C.-Y.
10.1101/2022.05.03.490475 — cancer biology — Posted on 2022-05-04
3798 Bioprinting microporous functional living materials from protein-based core-shell microgels
Ou, Y.; Cao, S.; Zhu, H.; Guo, C.; Zhang, Y.; Yan, W.; Xin, F.; Narita, M.; Yu, Z.; Knowles, T. P. J.
10.1101/2022.05.03.490444 — bioengineering — Posted on 2022-05-04
3801 Rank concordance of polygenic indices: Implications for personalised intervention and gene-environment interplay
Muslimova, D.; Pereira, R.; von Hinke, S.; Van Kippersluis, H.; Rietveld, C. A.; Meddens, S. F. W.
10.1101/2022.05.03.490435 — genomics — Posted on 2022-05-04
3802 Reversing Radiation-Induced Immunosuppression Using a New Therapeutic Modality
Courtney, C. M.; Sharma, S.; Fallgren, C.; Weil, M.; Chatterjee, A.; Nagpal, P.
10.1101/2022.05.03.490472 — genomics — Posted on 2022-05-04
3803 Subfunctionalized expression drives evolutionary retention of ribosomal protein paralogs in vertebrates
Xu, A. F.; Molinuevo, R.; Fazzari, E.; Tom, H.; Zhang, Z.; Menendez, J.; Casey, K. M.; Ruggero, D.; Hinck, L.; Pritchard, J. K.; Barna, M.
10.1101/2022.05.03.490441 — genetics — Posted on 2022-05-04
3807 Identifying and separating the processes underlying boreal forest understory community assembly
Itter, M. S.; Kaarlejärvi, E.; Laine, A.-L.; Hamberg, L.; Tonteri, T.; Vanhatalo, J.
10.1101/2022.05.03.490480 — ecology — Posted on 2022-05-04
3808 Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals
Iyer, A. A.; Hosamani, I.; Nguyen, J. D.; Cai, T.; Singh, S.; Beyer, L.; Zhang, H.; Jen, H.-I.; Yousaf, R.; Birol, O.; Sun, J. J.; Ray, R.; Raphael, Y.; Segil, N.; Groves, A. K.
10.1101/2022.05.03.490440 — developmental biology — Posted on 2022-05-04
3809 Using Shape Fluctuations to Probe the Mechanics of Stress Granules
Law, J. O.; Jones, C. M.; Stevenson, T. M.; Turner, M. S.; Kusumaatmaja, H.; Grellscheid, S. N.
10.1101/2022.05.03.490456 — cell biology — Posted on 2022-05-04
3811 Multifaceted role of RIMBP2 in promoting hearing in murine cochlear hair cells
Chai, R.; Li, G.-L.; Li, H.; Liao, M.; Chen, X.; Lu, L.; Guo, R.; Zhang, P.; Li, Y.; Zhang, Y.; Fang, Q.; Hu, Y.; Cai, J.; Chen, X.; Tang, M.; Gao, X.; He, S.
10.1101/2022.05.03.490398 — neuroscience — Posted on 2022-05-04
3813 Characterizing ketamine-induced dissociation using human intracranial neurophysiology: brain dynamics, network activity, and interactions with propofol
Tian, F.; Lewis, L. D.; Zhou, D. W.; Villegas, G. B.; Paulk, A. C.; Zelmann, R.; Peled, N.; Soper, D.; Mercado, L. A. S. C.; Peterfreund, R. A.; Aglio, L. S.; Eskandar, E. N.; Cosgrove, G. R.; Williams, Z. M.; Richardson, R. M.; Brown, E. N.; Akeju, O.; Cash, S. S.; Purdon, P. L.
10.1101/2022.05.02.490333 — neuroscience — Posted on 2022-05-04
3814 Cardiac interoception is enhanced in blind individuals
Radziun, D.; Korczyk, M.; Crucianelli, L.; Szwed, M.; Ehrsson, H. H.
10.1101/2022.05.02.490293 — neuroscience — Posted on 2022-05-04
3815 Learning of new associations invokes a major change in modulations of cortical beta oscillations in human adults
Pavlova, A.; Tyulenev, N.; Tretyakova, V.; Skavronskaya, V.; Nikolaeva, A.; Prokofyev, A.; Stroganova, T.; Chernyshev, B. V.
10.1101/2022.05.02.490325 — neuroscience — Posted on 2022-05-04
3817 Space-time resolved inference-based whole-brain neurophysiological mechanism imaging: application to resting-state alpha rhythm
Zhao, Y.; Boley, M.; Pelentritou, A.; Karoly, P.; Freestone, D.; Liu, Y.; Muthukumaraswamy, S. D.; Woods, W.; Liley, D.; Kuhlmann, L.
10.1101/2022.05.03.490402 — neuroscience — Posted on 2022-05-04
3818 Direct observation of the neural computations underlying a single decision
Steinemann, N. A.; Stine, G. M.; Trautmann, E. M.; Zylberberg, A.; Wolpert, D. M.; Shadlen, M. N.
10.1101/2022.05.02.490321 — neuroscience — Posted on 2022-05-04
3819 Using Transfer Learning for Automated Microbleed Segmentation
Dadar, M.; Zhernovaia, M.; Mahmoud, S.; Camicioli, R.; Maranzano, J.; Duchesne, S.
10.1101/2022.05.02.490283 — neuroscience — Posted on 2022-05-04
3820 State Dependent Coupling of Hippocampal Oscillations
Modi, B.; Guardamagna, M.; Stella, F.; Griguoli, M.; Cherubini, E.; Battaglia, F.
10.1101/2022.05.03.490415 — neuroscience — Posted on 2022-05-04
3821 Mixtures of large-scale dynamic functional brain network modes
Gohil, C.; Roberts, E.; Timms, R.; Skates, A.; Higgins, C.; Quinn, A.; Pervaiz, U.; van Amersfoort, J.; Notin, P.; Gal, Y.; Adaszewski, S.; Woolrich, M.
10.1101/2022.05.03.490453 — neuroscience — Posted on 2022-05-04
3822 A hippocampal-anterior thalamic circuit associated with learning rate in ageing
Frank, D.; Garo-Pascual, M.; Reyes Velasquez, P. A.; Frades, B.; Peled, N.; Zhang, L.; Strange, B.
10.1101/2022.05.03.490431 — neuroscience — Posted on 2022-05-04
3828 Excess glutamate release triggers subunit-specific homeostatic receptor scaling
Goel, P.; Han, Y.; Tran, N.; Nishimura, S.; Perry, S.; Sajnani, M.; Dickman, D.
10.1101/2022.05.03.490370 — neuroscience — Posted on 2022-05-04
3830 Sensitization to Ionizing Radiation by MEK inhibition is Dependent on SNAI2 in Fusion-negative Rhabdomyosarcoma
Hensch, N. R.; Bondra, K.; Wang, L.; Sreenivas, P.; Zhao, X. R.; Modi, P.; Vaseva, A. V.; Houghton, P. J.; Ignatius, M. S.
10.1101/2022.05.02.490343 — cancer biology — Posted on 2022-05-04
3831 Mapping mechanical stress in curved epithelia of designed size and shape
Marin-Llaurado, A.; Kale, S.; Ouzeri, A.; Sunyer, R.; Torres-Sanchez, A.; Latorre, E.; Gomez-Gonzalez, M.; Roca-Cusachs, P.; Arroyo, M.; Trepat, X.
10.1101/2022.05.03.490382 — biophysics — Posted on 2022-05-04
3833 Probing single cell fermentation flux and intercellular exchange networks via pH-microenvironment sensing and inverse modeling
Onesto, V.; Forciniti, S.; Alemanno, F.; Narayanankutty, K.; Chandra, A.; Prasad, S.; Azzariti, A.; Gigli, G.; Barra, A.; De Martino, A.; de Martino, D.; del Mercato, L. L.
10.1101/2022.05.03.490288 — biophysics — Posted on 2022-05-04
3836 Multi-task learning uncovers robust translation cis-regulatory features
Zheng, W.; Fong, J. H. C.; Wan, Y. K.; Chu, A. H. Y.; Huang, Y.; Wong, A. S. L.; Ho, J. W. K.
10.1101/2022.05.03.490410 — bioinformatics — Posted on 2022-05-04
3837 Extending the Boundaries of Cancer Therapeutic Complexity with Literature Data Mining
Niezni, D.; Taub-Tabib, H.; Harris, Y.; Sason-Bauer, H.; Amrusi, Y.; Azagury, D.; Avrashami, M.; Launer-Wachs, S.; Borchard, J.; Kusold, M.; Tiktinsky, A.; Hope, T.; Goldberg, Y.; Shamay, Y.
10.1101/2022.05.03.490286 — bioinformatics — Posted on 2022-05-04
3840 Defining marine bacterioplankton community assembly rules by contrasting the importance of environmental determinants and biotic interactions
Doane, M.; Ostrowski, M.; Brown, M. V.; Bramucci, A.; Bodrossy, L.; van de Kamp, J.; Bissett, A.; Steinberg, P. D.; Doblin, M. A.; Seymour, J. R.
10.1101/2022.05.02.490371 — ecology — Posted on 2022-05-04
3842 The role of geology in creating stream climate-change refugia along climate gradients
Ishiyama, N.; Sueyoshi, M.; Molinos, J. G.; Iwasaki, K.; Negishi, J. N.; Koizumi, I.; Nagayama, S.; Nakamura, F.
10.1101/2022.05.02.490355 — ecology — Posted on 2022-05-04
3846 Gene expression analysis of the Xenopus laevis early limb bud proximodistal axis.
Hudson, D. T.; Bromell, J. S.; Day, R. C.; McInnes, T.; Ward, J. M.; Beck, C. W.
10.1101/2022.05.03.490399 — developmental biology — Posted on 2022-05-04
3851 A neural mechanism for terminating decisions
Stine, G. M.; Trautmann, E. M.; Jeurissen, D.; Shadlen, M. N.
10.1101/2022.05.02.490327 — neuroscience — Posted on 2022-05-04
3854 Multi-omics analyses of drug repurposing reveal Acebutolol and Amiloride for osteoporosis treatment
Liu, D.-Y.; Greenbaum, J.; Yi, Q.-R.; Liang, S.; Zhang, Y.; Liu, J.-C.; Meng, X.-H.; Xiao, H.-M.; Deng, Y.; Tan, L.-J.; Deng, H.-w.
10.1101/2022.05.03.490380 — systems biology — Posted on 2022-05-04
3855 A transcriptional complex of FtMYB102 and FtbHLH4 coordinately regulates the accumulation of rutin in Fagopyrum tataricum
Zhang, D.; Mi, Y.; Li, Y.; Qian, G.; Vanhaelewyn, L.; Meng, X.; Yang, W.; Shi, Y.; Ma, P.; Wahab, A. t.; Chen, S.; Sun, W.
10.1101/2022.05.02.490379 — plant biology — Posted on 2022-05-04
3856 IDOL deficiency inhibits cholesterol-rich diet-induced atherosclerosis in rabbits
koike, t.; koike, y.; guo, y.; yang, d.; song, j.; xu, j.; zhao, x.; zhu, t.; li, r.; wen, b.; Sun, D.; rom, o.; Han, R.; fan, j.; Garcia-Barrio, m. t.; zhang, j.; chen, y. e.
10.1101/2022.05.03.490218 — physiology — Posted on 2022-05-04
3857 Computer simulations reveal pathogenicity and inheritance modes of hearing loss-causing germinal variants
Tsai, C.-Y.; Lu, Y.-C.; Chan, Y.-H.; Chang, Y.-Y.; Lin, S.-W.; Liu, T.-C.; Hsu, C.-J.; Chen, P.-L.; Yang, L.-W.; Wu, C.-C.
10.1101/2022.05.02.490275 — biophysics — Posted on 2022-05-04
3858 H3AGWAS : A portable workflow for Genome Wide Association Studies
Brandenburg, J.-T.; Clark, L.; Botha, G.; Panji, S.; Baichoo, S.; Fields, C. J.; Hazelhurst, S.
10.1101/2022.05.02.490206 — bioinformatics — Posted on 2022-05-04
3860 Taxonbridge: an R package to create custom taxonomies based on the NCBI and GBIF taxonomies
Veldsman, W. P.; Campli, G.; Dind, S.; Rech de Laval, V.; Drage, H.; Waterhouse, R. M.; Robinson-Rechavi, M.
10.1101/2022.05.02.490269 — bioinformatics — Posted on 2022-05-04
3863 Identification of a promiscuous conserved CTL epitope within the SARS-CoV-2 spike protein
Jiang, S.; Wu, S.; Zhao, G.; He, Y.; Guo, X.; Zhang, Z.; Hou, J.; Ding, Y.; Cheng, A.; Wang, B.
10.1101/2021.11.21.469172 — immunology — Posted on 2022-05-04
3865 Computational Mapping of the Human-SARS-CoV-2 Protein-RNA Interactome
Horlacher, M.; Oleshko, S.; Hu, Y.; Cantini, G.; Schinke, P.; Ghanbari, M.; Vergara, E. E.; Bittner, F.; Mueller, N.; Ohler, U.; Moyon, L.; Marsico, A.
10.1101/2021.12.22.472458 — bioinformatics — Posted on 2022-05-04
3867 Loading-Induced Bone Formation is Mediated by Wnt1 Induction in Osteoblast-Lineage Cells
Lawson, L.; Migotsky, N.; Chermside-Scabbo, C.; Shuster, J.; Joeng, K. S.; Civitelli, R.; Lee, B.; Silva, M.
10.1101/2022.02.28.482178 — cell biology — Posted on 2022-05-04
3868 Heritability of hippocampal functional and microstructural organisation
Bayrak, S.; Vos de Wael, R.; Schaare, H. L.; Hettwer, M. D.; Caldairou, B.; Bernasconi, A.; Bernasconi, N.; Bernhardt, B. C.; Valk, S. L.
10.1101/2021.11.10.468049 — neuroscience — Posted on 2022-05-04
3870 A Genetic Platform for Functionally Profiling Odorant Receptors Ex Vivo Using Olfactory Cilia.
Omura, M.; Takabatake, Y.; Lempert, E.; Benjamin-Hong, S.; D'Hulst, C.; Feinstein, P.
10.1101/2021.09.28.462154 — neuroscience — Posted on 2022-05-04
3871 Helminth egg derivatives as pro-regenerative immunotherapies
Maestas, D. R.; Chung, L.; Han, J.; Wang, X.; Sommerfeld, S. D.; Moore, E.; Hieu Nguyen, H.; Mejias, J. C.; Pena, A. N.; Zhang, H.; Hooks, J. S. T.; Chin, A. F.; Andorko, J. I.; Berlicke, C.; Krishnan, K.; Choi, Y.; Anderson, A. E.; Mahatme, R.; Mejia, C.; Eric, M.; Woo, J.; Ganguly, S.; Zack, D. J.; Housseau, F.; Pardoll, D. M.; Elisseeff, J. H.
10.1101/2022.05.02.490277 — bioengineering — Posted on 2022-05-04
3874 A selective bottleneck during host entry drives the evolution of new legume symbionts
Doin De Moura, G. G.; Mouffok, S.; Gaudu, N.; Cazale, A.-C.; Milhes, M.; Bulach, T.; Valiere, S.; Roche, D.; Ferdy, J.-B.; Masson-Boivin, C.; Capela, D.; Remigi, P.
10.1101/2022.03.03.482760 — evolutionary biology — Posted on 2022-05-04
3876 Regulation of translation by lysine acetylation in Escherichia coli
Feid, S. C.; Walukiewicz, H.; Nakayasu, E. S.; Wang, X.; Rao, C.; Wolfe, A. J.
10.1101/2022.05.02.490376 — microbiology — Posted on 2022-05-04
3878 IRG1 controls host responses to restrict Mycobacterium tuberculosis infection
Machelart, A.; Belhaouane, I.; Deboosere, N.; Poncin, I.; Saint-Andre, J.-P.; Pauwels, A.-M.; Song, O.-R.; Jouny, S.; Rouanet, C.; Poncet, A.; Marion, S.; Laine, W.; Kluza, J.; Muraille, E.; Beyaert, R.; Majlessi, L.; Canaan, S.; Brodin, P.; Hoffmann, E.
10.1101/761551 — immunology — Posted on 2022-05-04
3879 Extrinsic regulation of interneuron specification and migration
Pipicelli, F.; Baumann, N.; Di Giaimo, R.; Kyrousi, C.; Bonrath, R.; Jabaudon, D.; Cappello, S.
10.1101/2022.05.03.490384 — developmental biology — Posted on 2022-05-04
3881 Robust associations between white matter microstructure and general intelligence
Stammen, C.; Fraenz, C.; Grazioplene, R. G.; Schlüter, C.; Merhof, V.; Johnson, W.; Güntürkün, O.; DeYoung, C. G.; Genc, E.
10.1101/2022.05.02.490274 — neuroscience — Posted on 2022-05-04
3892 Describing Inhibitor Specificity for the Amino Acid Transporter LAT1 from Metainference Simulations
Hutchinson, K.; Silva, D. B.; Bohlke, J.; Clausen, C.; Thomas, A. A.; Bonomi, M.; Schlessinger, A.
10.1101/2022.05.03.490502 — biophysics — Posted on 2022-05-03
3893 A molecular plugin rescues GroEL/ES substrates from pre-folding oxidation
Dupuy, E.; Van der Verren, S.; Lin, J.; Wilson, M. A.; Dachsbeck, A.; Viela, F.; Latour, E.; Gennaris, A.; Vertommen, D.; Dufrene, Y. F.; Iorga, B. I.; Goemans, C. V.; Remaut, H.; Collet, J.-F.
10.1101/2022.05.03.490446 — biochemistry — Posted on 2022-05-03
3899 Cell detoxification of secondary metabolites by P4-ATPase mediated vesicle transport
Li, Y.; Ren, H.; Wang, F.; Chen, J.; Ma, L.; Chen, Y.; Li, X.; Fan, Y.; Jin, D.; Hou, L.; Zhou, Y.; Keyhani, N. O.; Pei, Y.
10.1101/2022.05.03.490477 — microbiology — Posted on 2022-05-03
3903 Variations of a theme - crystal forms of the amino acid transporter MhsT
Neumann, C. M. T.; Focht, D.; Trampari, S.; Lyons, J. A.; Nissen, P.
10.1101/2022.05.03.490450 — biochemistry — Posted on 2022-05-03
3904 HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation
Pearl, L.; Oberoi, J.; Aran-Guiu, X.; Outwin, E. A.; Schellenberger, P.; Roumeliotis, T. I.; Chaudhary, J. S.
10.1101/2022.05.03.490524 — biochemistry — Posted on 2022-05-03
3909 Viruses inhibit TIR gcADPR signaling to overcome bacterial defense
Leavitt, A.; Yirmiya, E.; Amitai, G.; Lu, A.; Garb, J.; Morehouse, B. R.; Hobbs, S. J.; Kranzusch, P. J.; Sorek, R.
10.1101/2022.05.03.490397 — microbiology — Posted on 2022-05-03
3910 Antibiotic-induced accumulation of lipid II sensitizes bacteria to antimicrobial fatty acids
Sidders, A. E.; Kedziora, K. M.; Beam, J. E.; Bui, D.; Parsons, J. B.; Rowe, S. E.; Conlon, B. P.
10.1101/2022.05.03.490474 — microbiology — Posted on 2022-05-03
3913 Carbapenem heteroresistance of KPC-producing Klebsiella pneumoniae results from tolerance, persistence and resistance.
Chiarelli, A.; Cabanel, N.; Rosinski-Chupin, I.; Obadia, T.; Ruimy, R.; Naas, T.; Bonnin, R.; Glaser, P.
10.1101/2022.05.03.490393 — microbiology — Posted on 2022-05-03
3914 Hunter-gatherer oral microbiomes are shaped by contact network structure
Musciotto, F.; Dobon, B.; Greenacre, M.; Mira, A.; Page, A. E.; Dyble, M.; Viguier, S.; Smith, D.; Chaudhary, N.; Salali, G. D.; Gerbault, P.; Schlaepfer, R.; Astete, L. H.; Ngales, M.; Gomez-Gardenes, J.; Latora, V.; Battiston, F.; Bertranpetit, J.; Vinicius, L.; Migliano, A. B.
10.1101/2022.05.03.489993 — microbiology — Posted on 2022-05-03
3915 The making of the oral microbiome in Agta hunter-gatherers
Dobon, B.; Musciotto, F.; Mira, A.; Greenacre, M.; Page, A. E.; Dyble, M.; Smith, D.; Viguier, S.; Schlaepfer, R.; Aguileta, G.; Astete, L. H.; Ngales, M.; Latora, V.; Battiston, F.; Vinicius, L.; Migliano, A. B.; Bertranpetit, J.
10.1101/2022.05.03.490437 — microbiology — Posted on 2022-05-03
3916 FoxP3-mediated blockage of ryanodine receptor 2 is the molecular basis for the contact-based suppression by regulatory T cells
Wang, X.; Geng, S.; Meng, J.; Kang, N.; Liu, X.; Xu, Y.; Lv, H.; Xu, Y.; Xu, X.; Song, X.; Zhang, B.; Wang, X.; Nuerbulati, N.; Zhang, Z.; Zhai, D.; Mao, X.; Sun, R.; Wang, X.; Wang, R.; Guo, J.; Chen, S. R. W.; Zhou, X.; Xia, T.; Qi, H.; Hu, X.; Shi, Y.
10.1101/2022.05.02.490213 — immunology — Posted on 2022-05-03
3919 Dietary derived Vitamin B12 protects the nematode Caenorhabditis elegans from thiol reducing agents.
Winter, A. D.; Tjahjono, E.; Beltran, L. J.; Johnstone, I. L.; Bulleid, N.; Page, A. P.
10.1101/2022.05.03.490466 — biochemistry — Posted on 2022-05-03
3920 Sensitivity of novel SARS-CoV-2 Omicron subvariants, BA.2.11, BA.2.12.1, BA.4 and BA.5 to therapeutic monoclonal antibodies
Yamasoba, D.; Kosugi, Y.; Kimura, I.; Fujita, S.; Uriu, K.; Ito, J.; Sato, K.; The Genotype to Phenotype Japan (G2P-Japan) Consortium,
10.1101/2022.05.03.490409 — microbiology — Posted on 2022-05-03
3921 Spatiotemporal landscape of SARS-CoV-2 pulmonary infection reveals Slamf9+Spp1+ macrophages promoting viral clearance and inflammation resolution
Cong, B.; Dong, X.; Yang, Z.; Yu, P.; Chai, Y.; Liu, J.; Zhang, M.; Zang, Y.; Kang, J.; Feng, Y.; Liu, Y.; Feng, W.; Deng, W.; Li, F.; Yu, Q.; Gu, Y.; Li, Z.; Liu, S.; Xu, X.; Zhong, N.; Ren, X.; Qin, C.; Liu, L.; Wang, J.; Cao, X.
10.1101/2022.05.03.490381 — immunology — Posted on 2022-05-03
3922 Protection from Omicron and other VOCs by Bivalent S-Trimer COVID-19 Vaccine
Su, D.; Li, X.; Huang, X.; He, C.; Zeng, C.; Wang, Q.; Mu, Z.; Qin, W.; Ambrosino, D.; Siber, G.; Clemens, R.; Liang, J. G.; Liang, P.; Jackson, N.; Xu, R.
10.1101/2022.05.03.490428 — immunology — Posted on 2022-05-03
3926 Acoustic regularities in infant-directed speech and song across cultures
Hilton, C. B.; Moser, C. J.; Bertolo, M.; Lee-Rubin, H.; Amir, D.; Bainbridge, C. M.; Simson, J.; Knox, D.; Glowacki, L.; Alemu, E.; Galbarczyk, A.; Jasienska, G.; Ross, C.; Neff, M. B.; Martin, A.; Cirelli, L. K.; Trehub, S. E.; Song, J.; Kim, M.; Schachner, A.; Vardy, T. A.; Atkinson, Q. D.; Salenius, A.; Andelin, J.; Antfolk, J.; Madhivanan, P.; Siddaiah, A.; Placek, C. D.; Salali, G. D.; Keestra, S.; Singh, M.; Collins, S. A.; Patton, J. Q.; Scaff, C.; Stieglitz, J.; CcariCutipa, S.; Moya, C.; Sagar, R. R.; Anyawire, M.; Mabulla, A.; Wood, B. M.; Krasnow, M. M.; Mehr, S. A.
10.1101/2020.04.09.032995 — animal behavior and cognition — Posted on 2022-05-03
3928 Temporal responses of bumblebee gustatoryneurons to sugars
Parkinson, R.; Kessler, S.; Scott, J.; Simpson, A.; Bu, J.; Mahdi, A.; Miriyala, A.; Wright, G.
10.1101/2022.02.28.482341 — neuroscience — Posted on 2022-05-03
3931 The nucleus bypasses obstacles by deforming like a drop with surface tension mediated by lamin A/C
Katiyar, A.; Zhang, J.; Antani, J. D.; Yu, Y.; Scott, K. L.; Lele, P. P.; Reinhart-King, C. A.; Sniadecki, N. J.; Roux, K. J.; Dickinson, R. B.; Lele, T. P.
10.1101/2022.03.10.483838 — cell biology — Posted on 2022-05-03
3936 Evaluation of nanopore sequencing for epigenetic epidemiology: a comparison with DNA methylation microarrays
Flynn, R.; Washer, S.; Jeffries, A. R.; Andrayas, A.; Shireby, G.; Kumari, M.; Schalkwyk, L. C.; Mill, J.; Hannon, E.
10.1101/2022.03.01.482537 — neuroscience — Posted on 2022-05-03
3938 Istaroxime metabolite PST3093 selectively stimulates SERCA2a and reverses disease-induced changes in cardiac function
Arici, M.; Ferrandi, M.; Barassi, P.; Hsu, S.-C.; Torre, E.; Luraghi, A.; Ronchi, C.; Chang, G.-J.; Peri, F.; Ferrari, P.; Bianchi, G.; Rocchetti, M.; Zaza, A.
10.1101/2021.08.17.455204 — pharmacology and toxicology — Posted on 2022-05-03
3939 Outbreak.info Research Library: A standardized, searchable platform to discover and explore COVID-19 resources
Tsueng, G.; Mullen, J.; Alkuzweny, M.; Cano, M. A.; Rush, B.; Haag, E.; Outbreak Curators, ; Latif, A. A.; Zhou, X.; Qian, Z.; Andersen, K. G.; Wu, C.; Su, A. I.; Gangavarapu, K.; Hughes, L. D.
10.1101/2022.01.20.477133 — bioinformatics — Posted on 2022-05-03
3943 Quantum pBac: An effective, high-capacity piggyBac-based gene integration vector system for unlocking gene therapy potential
Hua, W.-K.; Hsu, J. C.; Chen, Y.-C.; Chang, P. S.; Wen, K.-L. K.; Wang, P.-N.; Yu, Y.-S.; Chen, Y.-C.; Cheng, I.-C.; Wu, S. C.-Y.
10.1101/2022.04.29.490002 — cancer biology — Posted on 2022-05-03
3944 A novel Pyk2-derived peptide inhibits invadopodia-mediated breast cancer metastasis
Twafra, S.; Sokolik, C.; Sneh, T.; Srikanth, K.; Meirson, T.; Genna, A.; Chill, J.; Gil-Henn, H.
10.1101/2022.04.06.487297 — cancer biology — Posted on 2022-05-03
3946 Chromosome-level Genomes Reveal the Genetic Basis of Descending Dysploidy and Sex Determination in Morus Plants
Xia, Z.; Dai, X.; Fan, W.; Liu, C.; Zhang, M.; Bian, P.; Zhou, Y.; Li, L.; Zhu, B.; Liu, S.; Li, Z.; Wang, X.; Yu, M.; Xiang, Z.; Jiang, Y.; Zhao, A.
10.1101/2022.05.03.490406 — genomics — Posted on 2022-05-03
3948 Sequential functional differentiation of luminal epithelial cells regulated by maternal and embryonic signaling in the mouse endometrium
Wang, H.; Li, D.; Liu, J.; Jiang, Y.; Zhou, J.; Wang, Z.; Tang, X.; Zhang, Y.; Zhen, X.; Cao, Z.; Sheng, X.; Yang, C.; Yue, Q.; Ding, L.; Hu, Y.; Hu, Z.; Li, C.-J.; Yan, G.; Sun, H.
10.1101/2022.04.30.490140 — cell biology — Posted on 2022-05-03
3950 Pallidin function in drosophila surface glia regulates sleep and is dependent on amino acid availability
Li, H.; Aboudhiaf, S.; Parrot, S.; Scote-Blachon, C.; Benetollo, C.; Lin, J.-S.; Seugnet, L.
10.1101/2022.05.03.490434 — neuroscience — Posted on 2022-05-03
3953 Deeply conserved super-enhancers maintain stem cell pluripotency in placental mammals
Zhang, J.; Hua, J.; Wang, W.; Liao, M.; Li, N.; Zhou, Y.; Yue, W.; Zhu, Z.; Shen, Q.; Yu, S.; Wu, X.; Pan, Q.; Xu, W.; Zhang, R.; Wu, X.; Li, X.; Li, Y.; Wang, Y.; Zhang, S.; Lei, A.; Ding, X.; chen, x.; Yang, F.; Peng, S.; Li, Y.
10.1101/2022.05.03.490430 — cell biology — Posted on 2022-05-03
3956 Hidden Talents: Silent Gene Clusters Encoding Magnetic Organelle Biosynthesis in a Non-Magnetotactic Phototrophic Bacterium
Dziuba, M. V.; Paulus, A.; Schramm, L.; Awal, R. P.; Posfai, M.; Monteil, C.; Fouteau, S.; Uebe, R.; Schueler, D.
10.1101/2022.04.19.488322 — microbiology — Posted on 2022-05-03
3957 Observation of non-dormant persister cells reveals diverse modes of survival in antibiotic persistence
Umetani, M.; Fujisawa, M.; Okura, R.; Nozoe, T.; Suenaga, S.; Nakaoka, H.; Kussell, E.; Wakamoto, Y.
10.1101/2021.10.28.466227 — microbiology — Posted on 2022-05-03
3958 Sub-communities of the vaginal ecosystem in pregnant and non-pregnant women.
Symul, L.; Jeganathan, P.; Costello, E.; France, M.; Bloom, S. M.; Ravel, J.; Kwon, D. S.; Relman, D. A.; Holmes, S. P.
10.1101/2021.12.10.471327 — microbiology — Posted on 2022-05-03
3960 Parallel Factor Analysis for multidimensional decomposition of fNIRS data
Husser, A. M.; Caron-Desrochers, L.; Tremblay, J.; Vannasing, P.; Martinez-Montes, E.; Gallagher, A.
10.1101/806778 — neuroscience — Posted on 2022-05-03
3961 Inner hair cell synapse density influences auditory processing
Ji, L.; Martel, D. T.; Borges, B. C.; Wu, C.; Liberman, M. C.; Shore, S. E.; Corfas, G.
10.1101/2022.05.02.490340 — neuroscience — Posted on 2022-05-03
3962 CaV1 and CaV2 calcium channels mediate the release of distinct pools of synaptic vesicles
Mueller, B. D.; Merrill, S. A.; Watanabe, S.; Liu, P.; Singh, A.; Cherry, A.; Silva, M.; Wang, Z.-W.; Jorgensen, E. M.
10.1101/2022.05.03.490438 — neuroscience — Posted on 2022-05-03
3964 Hidden multivalency in phosphatase recruitment by a disordered AKAP scaffold
Watson, M.; Almeida, T.; Ray, A.; Hanack, C.; Elston, R.; Btesh, J.; McNaughton, P.; Stott, K.
10.1101/2021.05.23.445342 — biophysics — Posted on 2022-05-03
3966 3D MRI atlases of congenital aortic arch anomalies and normal fetal heart: application to automated multi-label segmentation
Uus, A. U.; van Poppel, M. P. M.; Steinweg, J. K.; Grigorescu, I.; Egloff Collado, A.; Ramirez Gilliland, P.; Roberts, T. A.; Hajnal, J. V.; Rutherford, M. A.; Lloyd, D. F. A.; Pushparajah, K.; Deprez, M.
10.1101/2022.01.16.476503 — bioinformatics — Posted on 2022-05-03
3970 Integrated view and comparative analysis of baseline protein expression in mouse and rat tissues
Wang, S.; Garcia-Seisdedos, D.; Prakash, A.; Kundu, D. J.; Collins, A.; George, N.; Fexova, S.; Moreno, P.; Papatheodorou, I.; Jones, A. R.; Vizcaino, J. A.
10.1101/2021.12.20.473413 — bioinformatics — Posted on 2022-05-03
3971 An integrated view of baseline protein expression in human tissues
Prakash, A.; Garcia-Seisdedos, D.; Wang, S.; Kundu, D. J.; Collins, A.; George, N.; Moreno, P.; Papatheodorou, I.; Jones, A. R.; Vizcaino, J. A.
10.1101/2021.09.10.459811 — bioinformatics — Posted on 2022-05-03
3974 Deep multi-omic network fusion for marker discovery of Alzheimer's Disease
Xie, L.; Raj, Y.; Varathan, P.; He, B.; Nho, K.; Salama, P.; Saykin, A. J.; Yan, J.
10.1101/2022.05.02.490336 — systems biology — Posted on 2022-05-03
3975 TIR-catalyzed ADP-ribosylation reactions produce signaling molecules for plant immunity
Jia, A.; Huang, S.; Song, W.; Wang, J.; Meng, Y.; Sun, Y.; Xu, L.; Laessle, H.; Jirschitzka, J.; Hou, J.; Zhang, T.; Yu, W.; Hessler, G.; Li, E.; Ma, S.; Yu, D.; Gebauer, J.; Baumann, U.; Liu, X.; Han, Z.; Chang, J.; Parker, J. E.; Chai, J.
10.1101/2022.05.02.490369 — plant biology — Posted on 2022-05-03
3977 Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2
Schmidt, H.; Zhang, M.; Mourelatos, H.; Sanchez-Rivera, F. J.; Lowe, S. W.; Ventura, A.; Leslie, C. S.; Pritykin, Y.
10.1101/2022.05.02.490368 — genomics — Posted on 2022-05-03
3983 The network makeup artist (NORMA-2.0): Distinguishing annotated groups in a network using innovative layout strategies
Karatzas, E.; Koutrouli, M.; Baltoumas, F. A.; Papanikolopoulou, K.; Bouyioukos, C.; Pavlopoulos, G.
10.1101/2022.03.02.482621 — bioinformatics — Posted on 2022-05-02
3985 Detection of pseudouridine modifications and type I/II hypermodifications in human mRNAs using direct, long-read sequencing
Tavakoli, S.; Nabizadehmashhadtoroghi, M.; Makhamreh, A.; Gamper, H.; Rezapour, N.; Hou, Y.-M.; Wanunu, M.; Rouhanifard, S. H.
10.1101/2021.11.03.467190 — genomics — Posted on 2022-05-02
3986 The swan genome and transcriptome: its not all black and white
Karawita, A. C.; Cheng, Y.; Chew, K. Y.; Challgula, A.; Kraus, R.; Mueller, R. C.; Tong, M. Z. W.; Hulme, K. D.; Beielefeldt-Ohmann, H.; Steele, L. E.; Wu, M.; Sng, J. D.; Noye, E.; Bruxner, T. J.; Au, G. G.; Lowthe, S.; Blommaert, J.; Suh, A.; McCauley, A. J.; Kaur, P.; Olga, D.; Aiden, E.; Fedrigo, O.; Formenti, G.; Mountcastle, J.; Chow, W.; Martin, F. J.; Ogeh, D. N.; Thiaud-Nissen, F.; Howe, K.; Collins, J.; Tracey, A.; Smith, J.; Kuo, R. I.; Renfree, M. b.; Kimura, T.; Sakoda, Y.; McDougall, M.; Spencer, H. G.; Pyne, M.; Tolf, C.; Waldenstrom, J.; Jarvis, E. D.; Baker, M. L.; Burt, D. W.
10.1101/2022.05.02.490350 — genomics — Posted on 2022-05-03
3987 Convergence on reduced aggression through shared behavioral traits in multiple populations of Astyanax mexicanus
Rodriguez-Morales, R.; Gonzalez-Lerma, P.; Yuiska, A.; Han, J. H.; Guerra, Y.; Crisostomo, L.; Keene, A. C.; Duboue, E.; Kowalko, J. E.
10.1101/2022.05.02.490357 — evolutionary biology — Posted on 2022-05-02
3988 Sequential functional differentiation of luminal epithelial cells regulated by maternal and embryonic signaling in the mouse endometrium
Wang, H.; Li, D.; Liu, J.; Jiang, Y.; Zhou, J.; Wang, Z.; Tang, X.; Zhang, Y.; Zhen, X.; Cao, Z.; Sheng, X.; Yang, C.; Yue, Q.; Ding, L.; Hu, Y.; Hu, Z.; Li, C.-J.; Yan, G.; Sun, H.
10.1101/2022.04.30.490140 — cell biology — Posted on 2022-05-02
3990 Deconvoluting signals downstream of growth and immune receptor kinases by phosphocodes of the BSU1 family phosphatases
Park, C. H.; Bi, Y.; Youn, J.-H.; Kim, S.-H.; Kim, J.-G.; Xu, N.; Shrestha, R.; Burlingame, A. L.; Xu, S.-L.; Mudgett, M. B.; Kim, S.-K.; Kim, T.-W.; Wang, Z.-Y.
10.1101/685610 — plant biology — Posted on 2022-05-02
3992 Vasopressin acts as a synapse organizer in limbic regions by boosting PSD95 and GluA1 expression
Zhang, L.; Padilla-Flores, T.; Hernandez, V. S.; Zetter, M. A.; Campos-Lira, E.; Escobar, L. I.; Millar, R. P.; Eiden, L. E.
10.1101/2020.11.07.373027 — neuroscience — Posted on 2022-05-02
3993 GeneVector: Identification of transcriptional programs using dense vector representations defined by mutual information.
Ceglia, N.; Sethna, Z.; Uhlitz, F.; Bojilova, V.; Rusk, N.; Burman, B.; Chow, A.; Salehi, S.; Kabeer, F.; Aparicio, S. H.; Greenbaum, B. D.; Shah, S. P.; McPherson, A.
10.1101/2022.04.22.487554 — bioinformatics — Posted on 2022-05-02
3994 Highly dense and scalable protein arrays for single-molecule studies
Aksel, T.; Qian, H.; Hao, P.; Indermuhle, P. F.; Inman, C.; Paul, S.; Chen, K.; Seghers, R.; Robinson, J. K.; De Garate, M.; Nortman, B.; Tan, J.; Hendricks, S.; Sankar, S.; Mallick, P.
10.1101/2022.05.02.490328 — bioengineering — Posted on 2022-05-02
3995 Insight into RNA-DNA primer length counting by human primosome
Baranovskiy, A. G.; Lisova, A. E.; Morstadt, L. M.; Babayeva, N. D.; Tahirov, T. H.
10.1101/2022.05.02.490354 — biochemistry — Posted on 2022-05-02
3996 Cancer malignancy is correlated with up-regulation of PCYT2-mediated glycerol phosphate modification of α-dystroglycan
Umezawa, F.; Natsume, M.; Fukusada, S.; Nakajima, K.; Yamasaki, F.; Kawashima, H.; Kuo, C.-W.; Khoo, K.-H.; Shimura, T.; Yagi, H.; Kato, K.
10.1101/2021.10.25.465649 — biochemistry — Posted on 2022-05-02
3998 The antique genetic plight of the Mediterranean monk seal (Monachus monachus)
Salmona, J.; Dayon, J.; Lecompte, E.; Karamanlidis, A. A.; Aguilar, A.; Fernandez de Larrinoa, P.; Pires, R.; Mo, G.; Panou, A.; Agnesi, A.; Borrell, A.; Danyer, E.; Öztürk, B.; Tonay, A. M.; Anestis, A. K.; Gonzalez, L. M.; Dendrinos, P.; Gaubert, P.
10.1101/2021.12.23.473149 — genetics — Posted on 2022-05-02
3999 Improved detection of evolutionary selection highlights potential bias from different sequencing strategies in complex genomic-regions
Hayeck, T. J.; Li, Y.; Mosbruger, T. L.; Bradfield, J. P.; Gleason, A. G.; Damianos, G.; Shaw, G. T.-w.; Duke, J. L.; Conlin, L. K.; Turner, T. N.; Sarmady, M.; Fernandez-Vina, M. A.; Monos, D. S.
10.1101/2021.09.28.462165 — genetics — Posted on 2022-05-02
4000 Damaraland mole-rats are not obligate cooperative breeders
Thorley, J.; Bensch, H.; Finn, K.; Clutton-Brock, T.; Zöttl, M.
10.1101/2021.12.08.471794 — ecology — Posted on 2022-05-02
4002 Long-term population decline of a genetically homogenous continental-wide top Arctic predator
Gousy-Leblanc, M.; Therrien, J.-F.; Broquet, T.; Rioux, D.; Curt-Grand-Gaudin, N.; Tissot, N.; Tissot, S.; Szabo, I.; Wilson, L.; Evans, J. T.; Bowes, V.; Gauthier, G.; Wiebe, K. L.; Yannic, G.; Lecomte, N.
10.1101/2022.04.29.490071 — ecology — Posted on 2022-05-02
4004 A conserved enzyme found in diverse human gut bacteria interferes with anticancer drug efficacy
Spanogiannopoulos, P.; Kyaw, T. S.; Guthrie, B. G. H.; Bradley, P. H.; Lee, J. V.; Melamed, J.; Malig, Y. N. A.; Lam, K. N.; Gempis, D.; Sandy, M.; Kidder, W.; van Blarigan, E. L.; Atreya, C.; Venook, A.; Gerona, R. R.; Goga, A. N.; Pollard, K. S.; Turnbaugh, P.
10.1101/820084 — microbiology — Posted on 2022-05-02
4005 Develop an efficient and specific AAV-based labeling system for Muller glia in mice
Gao, Y.; Fang, K.; Yan, Z.; Zhang, H.; Geng, G.; Wu, W.; Xu, D.; Zhang, H.; Zhong, N.; Wang, Q.; Cai, M.; Zuo, E.; Yang, H.
10.1101/2021.12.10.472182 — neuroscience — Posted on 2022-05-02
4006 Intermittent brain network reconfigurations and the resistance to social media influence
Lima Dias Pinto, I. I.; Rungratsameetaweemana, N.; Flaherty, K.; Periyannan, A.; Meghdadi, A.; Richard, C.; Berka, C.; Bansal, K.; Omar Garcia, J.
10.1101/2021.12.07.471625 — neuroscience — Posted on 2022-05-02
4008 EGR2 promoter antisense RNA coordinates chromatin remodeling and spatial genome organization in Schwann cells.
Moreno, M.-M.; Karambizi, D.; Hwang, H.; Fregoso, K.; Chen, J.-S.; Fajardo, J. E.; Fiser, A.; Tapinos, N.
10.1101/2022.05.02.490330 — neuroscience — Posted on 2022-05-02
4011 Powdery mildew effectors AVRA1 and BEC1016 target the ER J-domain protein HvERdj3B required for immunity in barley
Li, Z.; Velasquez-Zapata, V.; Elmore, J. M.; Li, X.; Xie, W.; Banerjee, S.; Jorgensen, H. J. L.; Pedersen, C.; Wise, R. P.; Thordal-Christensen, H.
10.1101/2022.04.27.489729 — plant biology — Posted on 2022-05-02
4016 Extreme tolerable winds for seabirds are determined by morphology
Nourani, E.; Safi, K.; de Grissac, S.; Anderson, D. J.; Cole, N. C.; Fell, A.; Gremillet, D.; Lerma, M.; McKee, J. L.; Pichegru, L.; Provost, P.; Rattenborg, N. C.; Ryan, P. G.; Santos, C. D.; Schoombie, S.; Tatayah, V.; Weimerskirch, H.; Wikelski, M.; Shepard, E.
10.1101/2022.05.02.490292 — animal behavior and cognition — Posted on 2022-05-02
4017 A chromosome-length genome assembly and annotation of blackberry (Rubus argutus, cv. Hillquist)
Bruna, T.; Aryal, R.; Dudchenko, O.; Sargent, D. J.; Mead, D.; Buti, M.; Cavallini, A.; Hytönen, T.; Andres, J.; Pham, M.; Weisz, D.; Mascagni, F.; Usai, G.; Natali, L.; Bassil, N.; Fernandez, G. E.; Lomsadze, A.; Armour, M.; Olukolu, B. A.; Poorten, T. J.; Britton, C.; Davik, J.; Ashrafi, H.; Aiden, E. L.; Borodovsky, M.; Worthington, M. L.
10.1101/2022.04.28.489789 — genomics — Posted on 2022-05-02
4019 Croatian Genetic Heritage: Renewed Y Chromosome Story a Decade Later
Primorac, D.; Skaro, V.; Projic, P.; Missoni, S.; Horjan Zanki, I.; Merkas, S.; Sarac, J.; Novokmet, N.; Ledic, A.; Makar, A.; Lauc, G.; Andelinovic, S.; Basic, Z.; Kruzic, I.; Neuberg, M.; Smolic, M.; Smolic, R.; Hrstic, I.; Trivanovic, D.; Konjhodzic, R.; Salihefendic, L.; Babic Jordamovic, N.; Marjanovic, D.
10.1101/2022.03.21.485134 — evolutionary biology — Posted on 2022-05-02
4022 Visualization of loop extrusion by DNA nanoscale tracing in single human cells
Beckwith, K. S.; Oedegaard Fougner, O.; Morero, N. R.; Barton, C.; Schueder, F.; Tang, W.; Alexander, S.; Peters, J.-M.; Jungmann, R.; Birney, E.; Ellenberg, J.
10.1101/2021.04.12.439407 — cell biology — Posted on 2022-05-02
4024 Quantitative stable-isotope probing (qSIP) with metagenomics links microbial physiology and activity to soil moisture in Mediterranean-climate grassland ecosystems
Greenlon, A.; Sieradzki, E. T.; Zablocki, O.; Koch, B. J.; Foley, M. M.; Kimbrel, J. A.; Hungate, B. A.; Blazewicz, S. J.; Nuccio, E. E.; Sun, C. L.; Chew, A.; Mancilla, C.-J.; Sullivan, M. B.; Firestone, M. K.; Pett-Ridge, J.; Banfield, J. F.
10.1101/2022.05.02.490339 — microbiology — Posted on 2022-05-02
4025 Inner hair cell synapse density influences auditory processing
Ji, L.; Martel, D. T.; Borges, B. C.; Wu, C.; Liberman, M. C.; Corfas, G.
10.1101/2022.05.02.490340 — neuroscience — Posted on 2022-05-02
4027 A resource for generating and manipulating human microglial states in vitro
Dolan, M.-J.; Therrien, M.; Jereb, S.; Kamath, T.; Atkeson, T.; Marsh, S.; Goeva, A.; Lojek, N.; Murphy, S.; White, C.; Joung, J.; Liu, B.; Limone, F.; Eggan, K.; Hacohen, N.; Bernstein, B.; Glass, C.; Leinonen, V.; Blurton-Jones, M.; Zhang, F.; Epstein, C. B.; Macosko, E.; Stevens, B.
10.1101/2022.05.02.490100 — neuroscience — Posted on 2022-05-02
4028 Mechanism of dopamine traveling waves in the striatum: theory and experiment
Matityahu, L.; Gilin, N.; Atamna, Y.; Tiroshi, L.; Wickens, J. R.; Goldberg, J. A.
10.1101/2022.04.19.488647 — neuroscience — Posted on 2022-05-02
4032 Evaluating and mitigating clinical samples matrix effects on TX-TL cell-free performance
Voyvodic, P.; Conejero, I.; Mesmoudi, K.; Renard, E.; Courtet, P.; Cattoni, D. I.; Bonnet, J.
10.1101/2022.05.02.489947 — synthetic biology — Posted on 2022-05-02
4034 Loss of Fgfr1 and Fgfr2 in Scleraxis-lineage cells leads to enlarged bone eminences and attachment cell death
Wernle, K. K.; Sonnenfelt, M. A.; Leek, C. C.; Ganji, E.; Tata, Z.; Offutt, C.; Paparella, E.; Shuff, J.; Sullivan, A. L.; Ornitz, D. M.; Killian, M. L.
10.1101/2021.09.20.461087 — physiology — Posted on 2022-05-02
4035 A Novel Chronic in vivo Oral Cadmium Exposure-Washout Mouse Model for Studying Cadmium Toxicity and Complex Diabetogenic Effects
Wong, W. P. S.; Wang, J. C.; Meyers, M. S.; Wang, N. J.; Sponenburg, R. A.; Allen, N. B.; Edwards, J. E.; El Muayed, M.
10.1101/2022.02.21.481351 — pharmacology and toxicology — Posted on 2022-05-02
4037 Pleiotrophin drives a pro-metastatic immune niche within the breast tumor microenvironment
Ganguly, D.; Schmidt, M. O.; Coleman, M.; Ngo, T.-V.; Sorrelle, N.; Dominguez, A. T.; Toombs, J.; Lewis, C.; Fang, Y.; Mora, F. V.; Gallego-Ortega, D.; Wellstein, A.; Brekken, R. A.
10.1101/2022.05.02.490334 — cancer biology — Posted on 2022-05-02
4040 Extracellular Vesicle (EV) Mitochondria and EV/HSP27 Mixtures Protect the Ischemic Brain Endothelium
Dave, K.; Stolz, D. B.; Reynolds, M. J.; Babidhan, R.; Dobbins, D. X.; Bhatia, T. N.; Yankello, H.; Reddy, R.; Bae, Y.; Leak, R. K.; Shiva, S.; Soundara Manickam, D.
10.1101/2021.10.29.466491 — bioengineering — Posted on 2022-05-02
4041 Leishmania allelic selection during experimental sand fly infection correlates with mutational signatures of oxidative DNA damage
Bussotti, G.; Li, B.; Pescher, P.; Vojtkova, B.; Louradour, I.; Pruzinova, K.; Sadlova, J.; Volf, P.; Spaeth, G. F.
10.1101/2022.05.02.490304 — evolutionary biology — Posted on 2022-05-02
4042 In situ structural analysis reveals membrane shape transitions during autophagosome formation
Bieber, A.; Capitanio, C.; Erdmann, P. S.; Fiedler, F.; Beck, F.; Lee, C.-W.; Li, D.; Hummer, G.; Schulman, B.; Baumeister, W.; Wilfling, F.
10.1101/2022.05.02.490291 — cell biology — Posted on 2022-05-02
4043 Two Competing Guilds as a Core Microbiome Signature for Chronic Diseases
Wu, G.; Xu, T.; Zhao, N.; Lam, Y. Y.; Ding, X.; Wei, D.; Fan, J.; Shi, Y.; Li, X.; Li, M.; Ji, S.; Wang, X.; Fu, H.; Zhang, F.; Peng, Y.; Shi, Y.; Zhang, C.; Zhao, L.
10.1101/2022.05.02.490290 — microbiology — Posted on 2022-05-02
4044 An Epitope-Focused Trypanosome-Derived Vaccine Platform Elicits High-Affinity Antibodies and Immunity Against Fentanyl Effects
Triller, G.; Vlachou, E. P.; Hashemi, H.; van Straaten, M.; Zeelen, J.; Kelemen, Y.; Baehr, C.; Marker, C.; Ruf, S.; Svirina, A.; Kruse, S.; Baumann, A.; Miller, A.; Bartel, M.; Pravetoni, M.; Stebbins, C. E.; Papavasiliou, F. N.; Verdi, J. P.
10.1101/2022.05.02.487070 — immunology — Posted on 2022-05-02
4045 Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
Parmasad, J.-L. A.; Ricke, K. M.; Stykel, M. G.; Buchner-Duby, B.; Lian, E.; Nguyen, B.; Lengacher, N. A.; Geertsma, H. M.; Bruce, A.; Callaghan, S. M.; Joselin, A.; Tomlinson, J. J.; Schlossmacher, M. G.; Stanford, W. L.; Brundin, P.; Ryan, S. D.; Rousseaux, M. W. C.
10.1101/2022.05.02.490309 — neuroscience — Posted on 2022-05-02
4047 Syntaxin Habc is required to open Unc18 to template SNARE assembly
Parra-Rivas, L. A.; Palfreyman, M. T.; Vu, T. N.; Jorgensen, E. M.
10.1101/2022.05.02.490315 — neuroscience — Posted on 2022-05-02
4049 Expression of YAP1-MAML2 and constitutively active YAP1 drive the formation of meningioma-like tumors in mice that resemble NF2-mutant meningiomas
Szulzewsky, F.; Arora, S.; Arakaki, A.; Sievers, P.; Bonnin, D. A. A.; Paddison, P. J.; Sahm, F.; Cimino, P. J.; Gujral, T.; Holland, E. C.
10.1101/2022.05.02.490337 — cancer biology — Posted on 2022-05-02
4051 Improving the RNA velocity approach using long-read single cell sequencing
Zhang, C.; Chen, W.; Fang, Y.; Chen, Z.; Xie, Y.; Chen, W.; Xie, Z.; Guo, M.; Wang, J.; Tan, C.; Wang, H.; Tang, C.
10.1101/2022.05.02.490352 — bioinformatics — Posted on 2022-05-02
4054 Nsp1 proteins of human coronaviruses HCoV-OC43 and SARS-CoV2 inhibit stress granule formation
Dolliver, S. M.; Kleer, M.; Bui-Marinos, M. P.; Ying, S.; Corcoran, J. A.; Khaperskyy, D.
10.1101/2022.05.02.490272 — microbiology — Posted on 2022-05-02
4055 The highly conserved stem-loop II motif is important for the lifecycle of astroviruses but dispensable for SARS-CoV-2
Janowski, A. B.; Jiang, H.; Fujii, C.; Owen, M. C.; Bricker, T. L.; Darling, T. L.; Harastani, H. H.; Seehra, K.; Tahan, S.; Jung, A.; Febles, B.; Blatter, J. A.; Handley, S. A.; Parikh, B. A.; Lulla, V.; Boon, A. C.; Wang, D.
10.1101/2022.04.30.486882 — microbiology — Posted on 2022-05-02
4057 BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection
Cao, Y. R.; Yisimayi, A.; Jian, F.; Song, W.; Xiao, T.; Wang, L.; Du, S.; Wang, J.; Li, Q.; Chen, X.; Wang, P.; Zhang, Z.; Liu, P.; An, R.; Hao, X.; Wang, Y.; Wang, J.; Feng, R.; Sun, H.; Zhao, L.; Zhang, W.; Zhao, D.; Zheng, J.; Yu, L.; Li, C.; Zhang, N.; Wang, R.; Niu, X.; Yang, S.; Song, X.; Zheng, L.; Li, Z.; Gu, Q.; Shao, F.; Huang, W.; Jin, R.; Shen, Z.; Wang, Y.; Wang, X.; Xiao, J.; Xie, X. S.
10.1101/2022.04.30.489997 — immunology — Posted on 2022-05-02
4060 Heterologously secreted MbxA from Moraxella bovis induces a membrane blebbing response of the human host cell
Erenburg, I. N.; Haensch, S.; Chacko, F. M.; Hamacher, A.; Wintgens, S.; Stuhldreier, F.; Poschmann, G.; Spitz, O.; Stuehler, K.; Wesselborg, S.; Hegemann, J.; Smits, S. H.; Weidtkamp-Peters, S.; Schmitt, L.
10.1101/2022.05.02.490299 — biochemistry — Posted on 2022-05-02
4065 The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency
Wahlen, S.; Matthijssens, F.; Van Loocke, W.; Taveirne, S.; Kiekens, L.; Persyn, E.; van Ammel, E.; De Vos, Z.; De Munter, S.; Matthys, P.; Van Nieuwerburgh, F.; Taghon, T.; Vandekerckhove, B.; Van Vlierberghe, P.; Leclercq, G.
10.1101/2022.05.02.490285 — immunology — Posted on 2022-05-02
4069 Computational Mapping of the Human-SARS-CoV-2 Protein-RNA Interactome
Horlacher, M.; Oleshko, S.; Hu, Y.; Cantini, G.; Schinke, P.; Ghanbari, M.; Vergara, E. E.; Bittner, F.; Mueller, N.; Ohler, U.; Moyon, L.; Marsico, A.
10.1101/2021.12.22.472458 — bioinformatics — Posted on 2022-05-02
4070 Perseverative behavior under uncertainty is enhanced by tryptophan depletion but diminished with subclinical obsessive-compulsive symptoms
Kanen, J. W.; Luo, Q.; Yellowlees, R.; Arntz, F. E.; Christmas, D. M.; Sahakian, B. J.; Apergis-Schoute, A. M.; Cardinal, R. N.; Robbins, T. W.
10.1101/2021.04.05.437619 — neuroscience — Posted on 2022-05-02
4073 OrganoID: a versatile deep learning platform for tracking and analysis of single-organoid dynamics
Matthews, J. M.; Schuster, B.; Kashaf, S. S.; Liu, P.; Ben-Yishay, R.; Ishay-Ronen, D.; Shen, L.; Weber, C.; Bielski, M.; Kupfer, S. S.; Bilgic, M.; Rzhetsky, A.; Tay, S.
10.1101/2022.01.13.476248 — bioengineering — Posted on 2022-05-02
4074 MITE infestation of germline accommodated by genome editing in Blepharisma
Seah, B. K. B.; Singh, M.; Emmerich, C.; Singh, A.; Woehle, C.; Huettel, B.; Byerly, A.; Stover, N. A.; Sugiura, M.; Harumoto, T.; Swart, E.
10.1101/2022.05.02.489906 — genomics — Posted on 2022-05-02
4079 CSF circulation and dispersion yield rapid clearancefrom intracranial compartments
Hornkjol, M.; Valnes, L. M.; Ringstad, G.; Rognes, M. E.; Eide, P. K.; Mardal, K.-A.; Vinje, V.
10.1101/2022.05.02.490257 — neuroscience — Posted on 2022-05-02
4082 Widespread employment of conserved C. elegans homeobox genes in neuronal identity specification
Reilly, M. B.; Tekieli, T.; Cros, C.; Aguilar, G. R.; Lao, J.; Toker, I. A.; Vidal, B.; Leyva-Diaz, E.; Bhattacharya, A.; Smith, J. J.; Kovacevic, I.; Gulez, B.; Fernandez, R.; Bradford, E. F.; Ramadan, Y. H.; Kratsios, P.; Bao, Z.; Hobert, O.
10.1101/2022.04.29.490095 — neuroscience — Posted on 2022-05-02
4083 Nr2f1 controls mitochondrial dynamics in mouse adult-born hippocampal neurons
Bonzano, S.; Michelon, F.; Crisci, I.; Molineris, I.; Neri, F.; Oliviero, S.; Beckervordersandforth, R.; Lie, D. C.; Peretto, P.; Bovetti, S.; Studer, M.; De Marchis, S.
10.1101/2022.03.25.485113 — neuroscience — Posted on 2022-05-02
4087 Distinct Mechanisms of Innate and Adaptive Immune Regulation Underlie Poor Oncologic Outcomes Associated with KRAS-TP53 Co-Alteration in Pancreatic Cancer
Datta, J.; Bianchi, A.; De Castro Silva, I.; Deshpande, N. U.; Cao, L. L.; Mehra, S.; Singh, S.; Rafie, C.; Sun, X.; Chen, X.; Dai, X.; Colaprico, A.; Sharma, P.; Dosch, A. R.; Pillai, A.; Hosein, P.; Nagathihalli, N.; Komanduri, K.; Wilson, J. M.; Ban, Y.; Merchant, N. B.
10.1101/2022.05.01.490244 — cancer biology — Posted on 2022-05-02
4089 Displacement and dissociation of oligonucleotidesduring DNA hairpin closure under strain
Ding, F.; Cocco, S.; Raj, S.; Manosas, M.; Spiering, M.; Bensimon, D.; Allemand, J.-F.; Croquette, V.
10.1101/2022.04.30.490171 — biophysics — Posted on 2022-05-02
4090 Resolution of the curse of dimensionality in single-cell RNA sequencing data analysis
Imoto, Y.; Nakamura, T.; Escolar, E. G.; Yoshiwaki, M.; Kojima, Y.; Yabuta, Y.; Katou, Y.; Yamamoto, T.; Hiraoka, Y.; Saitou, M.
10.1101/2022.05.02.490246 — bioinformatics — Posted on 2022-05-02
4095 Structure of V-ATPase from citrus fruit
Tan, Y. Z.; Keon, K. A.; Abdelaziz, R.; Imming, P.; Schulze, W.; Schumacher, K.; Rubinstein, J. L.
10.1101/2022.05.01.490144 — biochemistry — Posted on 2022-05-02
4100 Accelerated aging induced by stress in experimental murine ocular hypertension.
Xu, Q.; Rydz, C.; Nguyen Huu, V. A.; Rocha, L.; Palomino La Torre, C.; Lee, I.; Cho, W.; Jabari, M.; Donello, J.; Weinreb, R. N.; Lyon, D. C.; Ju, W.-K.; Foik, A.; Skowronska-Krawczyk, D.
10.1101/2022.05.01.490248 — molecular biology — Posted on 2022-05-02
4101 Spatial, Quantitative and Functional Deconstruction of Virus and Host Protein Interactions Inside Intact Cytomegalovirus Particles
Bogdanow, B.; Gruska, I.; Mühlberg, L.; Protze, J.; Hohensee, S.; Vetter, B.; Lehmann, M.; Wiebusch, L.; Liu, F.
10.1101/2022.05.02.490278 — microbiology — Posted on 2022-05-02
4103 GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma
Gargett, T.; Ebert, L. M.; Truong, N. T. H.; Kollis, P. M.; Sedivakova, K.; Yu, W.; Yeo, E. C. F.; Wittwer, N. L.; Gliddon, B. L.; Tea, M. N.; Ormsby, R.; Nowicki, J.; Poonnoose, S.; Vittorio, O.; Ziegler, D. S.; Pitson, S. M.; Brown, M. P.
10.1101/2022.05.01.490250 — immunology — Posted on 2022-05-02
4104 Minute-scale oscillatory sequences in medial entorhinal cortex
Gonzalo Cogno, S.; Obenhaus, H. A.; Jacobsen, R. I.; Donato, F.; Moser, M.-B.; Moser, E. I.
10.1101/2022.05.02.490273 — neuroscience — Posted on 2022-05-02
4109 Longitudinal 7T MRI reveals volumetric changes in subregions of human medial temporal lobe to sex hormone fluctuations
Zsido, R. G.; Williams, A. N.; Barth, C.; Serio, B.; Kurth, L.; Beyer, F.; Witte, V.; Villringer, A.; Sacher, J.
10.1101/2022.05.02.490281 — neuroscience — Posted on 2022-05-02
4110 Uncovering molecular iron compounds in the living human brain.
Filo, S.; Shaharabani, R.; Bar Hanin, D.; Adam, M.; Ben-David, E.; Schoffman, H.; Margalit, N.; Habib, N.; Shahar, T.; Mezer, A.
10.1101/2022.05.02.490254 — neuroscience — Posted on 2022-05-02
4111 Biomechanics and hydraulics of Opuntia ficus-indica roots exposed to extreme drought
Cuneo, I. F.; Barrientos-Sanhueza, C.; Hormazabal-Pavat, V.; Cargnino-Cisternas, D.
10.1101/2022.05.01.490238 — plant biology — Posted on 2022-05-02
4113 Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology
Bhatia^, H.; Larsson^, A. T.; Calizo^, A.; Pollard, K.; Zhang, X.; Conniff, E.; Tibbitts, J. F.; Osum, S. H.; Williams, K. B.; Crampton, A. L.; Jubenville, T.; Schefer, D.; Yang, K.; Lyu, Y.; Bade, J.; Pino, J. C.; Gosline, S. J.; Pratilas, C. A.; Largaespada, D. A.; Wood, D. K.; Hirbe, A. C.
10.1101/2022.04.29.490078 — cancer biology — Posted on 2022-05-02
4114 Genomic characteristics and clinical significance of CD56+ Circulating Tumor Cells in Small Cell Lung Carcinoma
Ricordel, C.; Chaillot, L.; Vlachavas, E.-I.; Logotheti, M.; Jouannic, A.; Desvallees, T.; Lecuyer, G.; Aubry, M.; Kontogianni, G.; Mastrokalou, C.; Jouan, F.; Jarry, U.; Corre, R.; Le Guen, Y.; Guillaudeux, T.; Lena, H.; Chatziioannou, A.; Pedeux, R.
10.1101/2022.04.30.487775 — cancer biology — Posted on 2022-05-02
4118 Engineering bacterial blight-resistant plants through CRISPR/Cas9-targeted editing of the MeSWEET10a promoter in cassava
Wang, Y.; Geng, M.; Pan, R.; Zhang, T.; Zhen, X.; Che, Y.; Li, R.; Liu, J.; Chen, Y.; Guo, J.; Yao, Y.
10.1101/2022.03.02.482644 — plant biology — Posted on 2022-05-02
4120 Exocytosis of the silicified cell wall of diatoms involves extensive membrane disintegration
de Haan, D.; Aram, L.; Peled-Zehavi, H.; Addadi, Y.; Ben Joseph, O.; Rotkopf, R.; Elad, N.; Rechav, K.; Gal, A.
10.1101/2021.09.14.460270 — cell biology — Posted on 2022-05-02
4121 Decreased in vitro dihydroartemisinin sensitivity in malaria parasites infecting sickle cell disease patients
Gnondjui, A. A.; Toure, A. O.; Ako, B. A.; Koui, S. T.; Assohoun, S. E.; Gbessi, E. A.; N'guessan, L. T.; Tuo, K.; Beorou, S.; Assi, S. B.; Yapo, F.; Sanogo, I.; Jambou, R.
10.1101/2022.04.29.490119 — microbiology — Posted on 2022-05-02
4122 Human Lung-resident Mucosal-Associated Invariant T cells are Abundant, Express Antimicrobial Proteins, and are Cytokine Responsive
Meermeier, E.; Zheng, C.; Soma, S.; Worley, A.; Weiss, D.; Modlin, R.; Swarbrick, G.; Karamooz, E.; Khuzwayo, S.; Wong, E.; Gold, M.; Lewinsohn, D.
10.1101/2022.04.28.489781 — immunology — Posted on 2022-05-02
4125 CORK1, a LRR-Malectin Receptor Kinase for Cellooligomer Perception in Arabidopsis thaliana
Tseng, Y.-H.; Scholz, S. S.; Fliegmann, J.; Krüger, T.; Gandhi, A.; Kniemeyer, O.; Brakhage, A. A.; Oelmüller, R.
10.1101/2022.04.29.490029 — plant biology — Posted on 2022-05-02
4127 Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas
Harpaz, N.; Mittelman, T.; Beresh, O.; Griess, O.; Furth, N.; Salame, T. M.; Oren, R.; Fellus-Alyagor, L.; Harmelin, A.; Alexandrescu, S.; Marques, J. G.; Filbin, M. G.; Ron, G.; Shema, E.
10.1101/2021.11.02.466907 — cancer biology — Posted on 2022-05-02
4129 caliPER: A software for blood-free parametric Patlak mapping using PET/MRI input function.
Dassanayake, P.; Cui, L.; Finger, E.; Kewin, M.; Hadaway, J.; Soddu, A.; Jakoby, B.; Zuehlsdorff, S.; St Lawrence, K. S.; Moran, G.; Anazodo, U. C.
10.1101/2021.07.08.451713 — bioinformatics — Posted on 2022-05-02
4131 The capsid precursor protein of astrovirus VA1 is proteolytically processed intracellularly
Aguilera-Flores, C.; Lopez, T.; Sandoval-Jaime, C.; Perez, E. I.; Lopez, S.; DuBois, R. M.; Arias, C. F.
10.1101/2022.04.28.489973 — microbiology — Posted on 2022-05-02
4133 Immune defense in Drosophila melanogaster depends on diet, sex, and mating status
Rai, K. E.; Yin, H.; Bengo, A. L. C.; Cheek, M.; Courville, R.; Bagheri, E.; Ramezan, R.; Behseta, S.; Shahrestani, P.
10.1101/2022.05.01.490225 — physiology — Posted on 2022-05-01
4136 The network makeup artist (NORMA-2.0): Distinguishing annotated groups in a network using innovative layout strategies
Karatzas, E.; Koutrouli, M.; Baltoumas, F. A.; Paoanikolopoulou, K.; Bouyioukos, C.; Pavlopoulos, G.
10.1101/2022.03.02.482621 — bioinformatics — Posted on 2022-05-01
4137 Oscillatory and aperiodic neural activity jointly predict language learning
Cross, Z. R.; Corcoran, A. W.; Schlesewsky, M.; Kohler, M. J.; Bornkessel-Schlesewsky, I.
10.1101/2020.03.10.984971 — neuroscience — Posted on 2022-05-01
4139 Differential genetic variation underlying Ammonium and Nitrate responses in Arabidopsis thaliana
Katz, E.; Knapp, A.; Lensink, M.; Stefani, J.; Li, J.-J.; Shane, E.; Tuermer-Lee, K.; Bloom, A. J.; Kliebenstein, D. J.
10.1101/2022.04.27.489730 — plant biology — Posted on 2022-05-01
4144 A transcriptional mechanism involving R-loop, m6A modification and RNA abasic sites regulates an enhancer RNA of APOE.
Watts, J. A.; Grunseich, C.; Rodriguez, Y.; Liu, Y.; Li, D.; Burdick, J. T.; Bruzel, A.; Crouch, R. J.; Mahley, R. W.; Wilson, S.; Cheung, V. G.
10.1101/2022.05.01.489793 — molecular biology — Posted on 2022-05-01
4145 Fc-engineered antibodies leverage neutrophils to drive control of Mycobacterium tuberculosis
Irvine, E. B.; Peters, J. M.; Lu, R.; Grace, P. S.; Sixsmith, J.; Wallace, A.; Schneider, M.; Shin, S.; Karpinski, W.; Hsiao, J. C.; van Woudenbergh, E.; Casadevall, A.; Bryson, B. D.; Cavacini, L.; Alter, G.; Fortune, S. M.
10.1101/2022.05.01.490220 — immunology — Posted on 2022-05-01
4151 Microbial metabolite butyrate-prodrug polymeric micelles promote gut health and treat food allergies
Wang, R.; Cao, S.; Bashir, M. E. H.; Hesser, L. A.; Su, Y.; Hong, S. M. C.; Thompson, A.; Culleen, E.; Sabados, M.; Dylla, N. P.; Campbell, E.; Alshaikh, A. A.; Shim, H.-N.; Wu, H.; Bao, R.; Wilson, D. S.; Nagler, C. R.; Hubbell, J. A.
10.1101/2022.05.01.490224 — bioengineering — Posted on 2022-05-01
4153 Role of aIF5B in archaeal translation initiation
Kazan, R.; Bourgeois, G.; Lazennec-Schurdevin, C.; Larquet, E.; Mechulam, Y.; Coureux, P.-D.; Schmitt, E.
10.1101/2022.05.01.490067 — biochemistry — Posted on 2022-05-01
4159 Elevator mechanism dynamics in a sodium-coupled dicarboxylate transporter
Kinz-Thompson, C. D.; Lopez Redondo, M.; Mulligan, C.; Sauer, D. B.; Marden, J. J.; Song, J.; Tajkhorshid, E.; Hunt, J. F.; Stokes, D. L.; Mindell, J. A.; Wang, D.-N.; Gonzalez, R. L.
10.1101/2022.05.01.490196 — biophysics — Posted on 2022-05-01
4161 Unifying genomics and transcriptomics in single cells with ResolveOME amplification chemistry to illuminate oncogenic and drug resistance mechanisms
Zawistowski, J. S.; Salas-Gonzalez, I.; Morozova, T. V.; Blackinton, J. G.; Tate, T.; Arvapalli, D.; Velivela, S.; Harton, G. L.; Marks, J. R.; Hwang, E. S.; Weigman, V. J.; West, J. A.
10.1101/2022.04.29.489440 — genomics — Posted on 2022-05-01
4162 Genetic architecture of spatially complex color patterning in hybrid Mimulus
Cooley, A. M.; Schlutius, C.; Matthews, M.; Zheng, X.; Thomas, D.; Edger, P.; Platts, A.; George, L.; Williams, A.; LaFountain, A.; Hundley, D.; Yuan, Y.-w.; Twyford, A. D.; Puzey, J. D.
10.1101/2022.04.29.490035 — genetics — Posted on 2022-05-01
4165 Multi-echo Quantitative Susceptibility Mapping: How to Combine Echoes for Accuracy and Precision at 3 T
Biondetti, E.; Karsa, A.; Grussu, F.; Battiston, M.; Yiannakas, M. C.; Thomas, D. L.; Shmueli, K.
10.1101/2021.06.14.448385 — neuroscience — Posted on 2022-05-01
4167 Dynamic tripartite construct of interregional engram circuits underlies forgetting of extinction memory
Gu, X.; Wu, Y.-J.; Zhu, J.-J.; Wu, X.-R.; Wang, Q.; Yi, X.; Lin, Z.-J.; Jiao, Z.-H.; Xu, M.; Jiang, Q.; Li, Y.; Xu, N.-J.; Zhu, M. X.; Wang, L.-Y.; Xu, T.-L.; Li, W.-G.
10.1101/2022.04.30.490143 — neuroscience — Posted on 2022-05-01
4168 The Breast Cancer Epigenomics Track Hub
Ambrosini, G.; Agnoletto, A.; Brisken, C.; Bucher, P.
10.1101/2022.05.01.490187 — cancer biology — Posted on 2022-05-01
4169 A DNA segregation module for synthetic cells
Tran, M. P.; Chatterjee, R.; Dreher, Y.; Fichtler, J.; Jahnke, K.; Hilbert, L.; Zaburdaev, V.; Göpfrich, K.
10.1101/2022.04.30.489979 — biophysics — Posted on 2022-05-01
4176 Boosting polygenic risk scores
Klinkhammer, H.; Staerk, C.; Maj, C.; Krawitz, P.; Mayr, A.
10.1101/2022.04.29.489836 — bioinformatics — Posted on 2022-05-01
4188 Increased glucose availability sensitizes pancreatic cancer to chemotherapy
Vaziri-Gohar, A.; Hue, J. J.; Graor, H. J.; Abbas, A.; Zarei, M.; Hajihassani, O.; Titomihelakis, G.; Feczko, J.; Rathore, M.; Wang, R.; Zarei, M.; Goudarzi, M.; Zhang, R.; Willard, B.; Zhang, L.; Wang, G.-M.; Tatsuoka, C.; Salvino, J. M.; Bederman, I.; Brunengraber, H.; Lyssiotis, C. A.; Brody, J. R.; Winter, J. M.
10.1101/2022.04.29.490090 — cancer biology — Posted on 2022-05-01
4189 TME induced TRAIL secretion from engineered macrophages for anti-tumor therapy
Yin, X.; huang, x.; Deng, B.; Zhou, H.; Shi, B.; Liu, J.; Shan, X.; fang, x.; Zhang, L.
10.1101/2022.04.30.490137 — cancer biology — Posted on 2022-05-01
4190 Glutamine is essential for overcoming theimmunosuppressive microenvironment in malignant salivary gland tumors
Cao, S.; Hung, Y.-W.; Wang, Y.-C.; hung, Y.; Qi, Y.; Ouyang, C.; Zhong, X.; Hu, W.; Coblentz, A.; Maghami, E.; Sun, Z.; Lin, H. H.; Ann, D. K.
10.1101/2022.04.29.490103 — cancer biology — Posted on 2022-05-01
4191 Sexually dimorphic activation of innate antitumour immunity prevents adrenocortical carcinoma development
Wilmouth, J. J.; Olabe, J.; Garcia-Garcia, D.; Lucas, C.; Guiton, R.; Roucher-Boulez, F.; Dufour, D.; Damon-Soubeyrand, C.; Sahut-Barnola, I.; Pointud, J.-C.; Renaud, Y.; Levasseur, A.; Tauveron, I.; Lefrancois-Martinez, A.-M.; Martinez, A.; Val, P.
10.1101/2022.04.29.489846 — cancer biology — Posted on 2022-05-01
4198 DysRegNet: Patient-specific and confounder-aware dysregulated network inference
Lazareva, O.; Louadi, Z.; Kersting, J.; Baumbach, J.; Blumenthal, D.; List, M.
10.1101/2022.04.29.490015 — bioinformatics — Posted on 2022-05-01
4199 Single cell transcriptional landscape of long non-coding RNAs orchestrating mouse heart development
Ramos, T. R.; Kim, S. Y.; Gillette, T.; Hill, J.; do Rego, T. G.; Maracaja-Coutinho, V.
10.1101/2022.04.29.490042 — bioinformatics — Posted on 2022-05-01
4200 A deep learning framework for structural variant discovery and genotyping
Popic, V.; Rohlicek, C.; Cunial, F.; Garimella, K. V.; Meleshko, D.; Hajirasouliha, I.
10.1101/2022.04.30.490167 — bioinformatics — Posted on 2022-05-01
4204 Imaging the structure and dynamic activity of retinal microglia and macrophage-like cells in the living human eye
Rui, Y.; Lee, D. M. W.; Zhang, M.; Snyder, V. C.; Raghuraman, R.; Gofas, E.; Mece, P.; Yadav, S.; Grieve, K.; Sahel, J.-A.; Errera, M.-H.; Rossi, E. A.
10.1101/2022.04.30.490173 — bioengineering — Posted on 2022-05-01
4205 Magnetic Enrichment of Immuno-Specific Extracellular Vesicles for Mass Spectrometry Using Biofilm-Derived Iron Oxide Nanowires
Pham, Q. N.; Winter, M.; Milanova, V.; Young, C.; Condina, M. R.; Hoffmann, P.; Pham, N. T. H.; Tung, T. T.; Losic, D.; Thierry, B.
10.1101/2022.05.01.490183 — bioengineering — Posted on 2022-05-01
4208 Heritability of Urinary Amines, Organic Acids, and Steroid Hormones in Children
Hagenbeek, F. A.; van Dongen, J.; Pool, R.; Harms, A. C.; Roetman, P. J.; Fanos, V.; van Keulen, B. J.; Walker, B. R.; Karu, N.; Hulshoff Pol, H. E.; Rotteveel, J.; Finken, M. J. J.; Vermeiren, R. R. J. M.; Kluft, C.; Bartels, M.; Hankemeier, T.; Boomsma, D. I.
10.1101/2022.04.29.489305 — genomics — Posted on 2022-05-01
4213 Evolution is not uniform along protein sequences
Bricout, R.; Weil, D.; Stroebel, D.; Genovesio, A.; Roest Crollius, H.
10.1101/2022.04.30.490124 — evolutionary biology — Posted on 2022-05-01
4215 Long-term population decline of a genetically homogenous continental-wide top Arctic predator
Gousy-Leblanc, M.; Therrien, J.-F.; Broquet, T.; Rioux, D.; Curt-Grand-Gaudin, N.; Tissot, N.; Tissot, S.; Szabo, I.; Wilson, L.; Evans, J. T.; Bowes, V.; Gauthier, G.; Wiebe, K. L.; Yannic, G.; Lecomte, N.
10.1101/2022.04.29.490071 — ecology — Posted on 2022-05-01
4216 Variant Polycomb complexes in Drosophila consistent with ancient functional diversity
Kang, H.; Cabrera, J. R.; Zee, B. M.; Kang, H. A.; Jobe, J. M.; Hegarty, M. B.; Barry, A. E.; Glotov, A.; Schwartz, Y. B.; Kuroda, M. I.
10.1101/2022.04.29.490092 — developmental biology — Posted on 2022-05-01
4217 A CXCL12 morphogen gradient uncovers lung endothelial heterogeneity and promotes distal vascular growth
Chandrasekaran, P.; Negretti, N. M.; Sivakumar, A.; Peers de Nieuburgh, M.; Wang, J.; Michki, N. S.; Chaudhry, F. N.; Wen, H.; Kaur, S.; Lu, M.; Zepp, J. A.; Young, L. R.; Sucre, J. M. S.; Frank, D. B.
10.1101/2022.04.30.490096 — developmental biology — Posted on 2022-05-01
4219 Toxicology assessment of manganese oxide nanomaterials with enhanced electrochemical properties using human in vitro models representing different exposure routes
Fernandez-Pampin, N.; Gonzalez Plaza, J. J.; Garcia, A.; Pena, E.; Rumbo, C.; Barros Garcia, R.; Martel, S.; Aparicio, S.; Tamayo-Ramos, J. A.
10.1101/2022.04.30.490128 — cell biology — Posted on 2022-05-01
4221 Sequential functional differentiation of luminal epithelial cells regulated by maternal and embryonic signaling in the mouse endometrium
Wang, H.; Li, D.; Liu, J.; Jiang, Y.; Zhou, J.; Wang, Z.; Tang, X.; Zhang, Y.; Zhen, X.; Cao, Z.; Sheng, X.; Yang, C.; Yue, Q.; Ding, L.; Hu, Y.; Hu, Z.; Li, C.-J.; Yan, G.; Sun, H.
10.1101/2022.04.30.490140 — cell biology — Posted on 2022-05-01
4223 The dual character of the inhibitory functions of CD6
Santos, R. F.; De Sousa Linhares, A.; Cardoso, M. S.; Novoa, A.; Luche, H.; Gartner, F.; Malissen, B.; Steinberger, P.; Davis, S.; Mallo, M.; Oliveira, L.; Carmo, A. M.
10.1101/2022.04.29.490054 — immunology — Posted on 2022-05-01
4224 INFLAMMATION INDUCED DOWNREGULATION OF SUCCINATE DEHYDROGENASE REGULATES ADRENOCORTICAL FUNCTION
Mateska, I.; Witt, A.; Hagag, E.; Sinha, A.; Yilmaz, C.; Thanou, E.; Sun, N.; Kolliniati, O.; Patschin, M.; Abdelmegeed, H.; Henneicke, H.; Kanczkowski, W.; Wielockx, B.; Tsatsanis, C.; Dahl, A.; Walch, A.; Li, K. W.; Peitzsch, M.; Chavakis, T.; Alexaki, V. I.
10.1101/2022.04.29.490066 — immunology — Posted on 2022-05-01
4225 An in situ quantitative map of initial human colorectal HIV transmission
Baharlou, H.; Canete, N. P.; Vine, E. E.; hu, k.; Yuan, D.; Sandgren, K. J.; Bertram, K. M.; Nasr, `Najla; Rhodes, J. W.; Gosselink, M.; Di Re, A.; Reza, F.; Ctercteko, G.; Pathma-Nathan, N. `; Collins, G.; Toh, J.; Patrick, E.; Haniffa, M. A.; Estes, J. D.; Byrne, S. N.; Cunningham, T. L.; Harman, A. N.
10.1101/2022.04.30.490175 — immunology — Posted on 2022-05-01
4227 NMDA-receptor-Fc-fusion constructs neutralize anti- NMDA receptor antibodies
Steinke, S.; Kirmann, T.; Nerlich, J.; Weichard, I.; Kuhn, P.; Bullmann, T.; Ritzau-Jost, A.; Rizalar, F. S.; Pruess, H.; Haucke, V.; Geis, C.; Hust, M.; Hallermann, S.
10.1101/2022.04.29.490085 — neuroscience — Posted on 2022-05-01
4234 A transcription factor module regulating stomatal formation is co-opted for the development of setae in the astomatous liverwort Marchantia polymorpha
Moriya, K. C.; Shirakawa, M.; Loue-Manifel, J.; Matsuda, Y.; Tamura, K.; Oka, Y.; Matsushita, T.; Hara-Nishimura, I.; Ingram, G.; Nishihama, R.; Goodrich, J.; Kohchi, T.; Shimada, T.
10.1101/2022.04.29.489008 — plant biology — Posted on 2022-05-01
4236 Taxonomically Restricted Genes are Associated with Responses to Biotic and Abiotic Stresses in Sugarcane (Saccharum spp.)
Cardoso-Silva, C. B.; Aono, A. H.; Mancini, M. C.; Sforca, D. A.; Silva, C. C.; Pinto, L. R.; Adams, K.; de Souza, A. P.
10.1101/2022.04.29.489768 — plant biology — Posted on 2022-05-01
4237 Leaf-level metabolic changes in response to drought affect daytime CO2 emission and isoprenoid synthesis
Ladd, S. N.; Daber, L. E.; Bamberger, I.; Kuebert, A.; Kreuzwieser, J.; Purser, G.; Ingrisch, J.; Deleeuw, J.; van Haren, J.; Meredith, L.; Werner, C.
10.1101/2022.04.29.490001 — plant biology — Posted on 2022-05-01
4239 Uncovering Additional Predictors of Urothelial Carcinoma from Voided Urothelial Cell Clusters Through a Deep Learning Based Image Preprocessing Technique
Levy, J.; Liu, X.; Marotti, J. D.; Kerr, D. A.; Gutmann, E. J.; Glass, R.; Dodge, C. P.; Suriawinata, A. A.; Vaickus, L. J.
10.1101/2022.04.30.490136 — pathology — Posted on 2022-05-01
4241 Quantum pBac: An effective, high-capacity piggyBac-based gene integration vector system for unlocking gene therapy potential
Hua, W.-K.; Hsu, J. C.; Chen, Y.-C.; Chang, P. S.; Wen, K.-L. K.; Wang, P.-N.; Yu, Y.-S.; Chen, Y.-C.; Cheng, I.-C.; Wu, S. C.-Y.
10.1101/2022.04.29.490002 — cancer biology — Posted on 2022-05-01
4243 Hypoxia-mediated regulation of DDX5 through decreased chromatin accessibility and post-translational targeting restricts R-loop accumulation
Leszczynska, K. B.; Dzwigonska, M.; Estephan, H.; Moehlenbrink, J.; Bowler, E.; Giaccia, A. J.; Mieczkowski, J.; Kaminska, B.; Hammond, E. M.
10.1101/2022.04.30.490097 — cancer biology — Posted on 2022-05-01
4245 microbeSEG: Accurate Cell Segmentation with OMERO Data Management
Scherr, T.; Seiffarth, J.; Wollenhaupt, B.; Neumann, O.; Schilling, M. P.; Kohlheyer, D.; Scharr, H.; Nöh, K.; Mikut, R.
10.1101/2022.04.29.489998 — bioinformatics — Posted on 2022-05-01
4248 Deep Learning-based Pseudo-Mass Spectrometry Imaging Analysis for Precision Medicine
Shen, X.; Shao, W.; Wang, C.; Liang, L.; Chen, S.; Zhang, S.; Rusu, M.; Snyder, M.
10.1101/2022.04.29.490098 — bioinformatics — Posted on 2022-05-01
4254 Colour polymorphism associated with a gene duplication in male wood tiger moths
Brien, M. N.; Orteu, A.; Yen, E. C.; Galarza, J. A.; Kirvesoja, J.; Pakkanen, H.; Wakamatsu, K.; Jiggins, C. D.; Mappes, J.
10.1101/2022.04.29.490025 — evolutionary biology — Posted on 2022-05-01
4257 Stability of the genetic structure of a wild wheat population across microhabitats over 36 years
Dahan-Meir, T.; Ellis, T. J.; Mafessoni, F.; Sela, H.; Manisterski, J.; Avivi-Ragolsky, N.; Raz, A.; Feldman, M.; Anikster, Y.; Nordborg, M.; Levy, A. A.
10.1101/2022.01.10.475641 — evolutionary biology — Posted on 2022-05-01
4258 The specific roles of renal macrophages in monitoring and clearing off intratubular particles
He, J.; Cao, Y.; Zhu, Q.; Wang, X.; Cheng, G.; Wang, Q.; Han, F.; Shi, P.; Shen, X. Z.
10.1101/2022.04.11.487834 — immunology — Posted on 2022-05-01
4259 Polycystin promotes renal fibrosis through EZH2
Wu, M.; Wang, Y.; Jing, Y.; Chen, D.; Lin, J.; Yuan, M.; Tan, B.; Huang, D.; Ye, C.
10.1101/2021.11.03.467035 — molecular biology — Posted on 2022-05-01