bioRxiv directory

Krivdova, G.; Voisin, V.; Schoof, E. M.; Marhon, S. A.; Murison, A. J.; McLeod, J. L.; Gabra, M.; Zeng, A. G.; Van Nostrand, E. L.; Aigner, S. J.; Shishkin, A. A.; Yee, B. A.; Hermans, K. G.; Trotman-Grant, A. G.; Mbong, N.; Kennedy, J. A.; Gan, O. I.; Wagenblast, E.; De Carvalho, D. D.; Salmena, L.; Minden, M. D.; Bader, G. D.; Yeo, G. W.; Dick, J. E.; Lechman, E. R.

10.1101/2021.07.30.454489 — cell biology — Posted on 2021-07-31

9 Elevated fear responses to threatening cues in rats with early life stress is associated with greater excitability and loss of gamma oscillations in ventral-medial prefrontal cortex

Bercum, F. M.; Navarro Gomez, M. J.; Saddoris, M. P.

10.1101/2021.07.28.454150 — neuroscience — Posted on 2021-07-31

10 Role of non-specific interactions in the phase-separation and maturation of macromolecules

Krishnan, R.; Ranganathan, S.; Maji, S. K.; Padinhateeri, R.

10.1101/2021.07.25.453674 — biophysics — Posted on 2021-07-31

11 Analytic Pearson residuals for normalization of single-cell RNA-seq UMI data

Lause, J.; Berens, P.; Kobak, D.

10.1101/2020.12.01.405886 — bioinformatics — Posted on 2021-07-31

12 Effects of domestication on neophobia: A comparison between the domesticated Bengalese finch (Lonchura striata var. domestica) and its wild ancestor, the white-rumped munia (Lonchura striata)

Suzuki, K.; Ikebuchi, M.; Kagawa, H.; Koike, T.; Okanoya, K.

10.1101/2021.03.23.436696 — animal behavior and cognition — Posted on 2021-07-31

13 Invertebrate methylomes provide insight into mechanisms of environmental tolerance and reveal methodological biases

Trigg, S. A.; Venkataraman, Y. R.; Gavery, M.; Roberts, S. B.; Bhattacharya, D.; Downey-Wall, A.; Eirin-Lopez, J. M.; Johnson, K. M.; Lotterhos, K. E.; Puritz, J. B.; Putnam, H. M.

10.1101/2021.03.29.437539 — genomics — Posted on 2021-07-31

14 Selection on growth rate and local adaptation drive genomic adaptation during experimental range expansions in the protist Tetrahymena thermophila

Moerman, F.; Fronhofer, E. A.; Altermatt, F.; Wagner, A.

10.1101/2021.02.04.429706 — evolutionary biology — Posted on 2021-07-31

15 Intraspecific interaction of host plant influences local distribution of specialist herbivores through metabolic alterations in leaves

Ohsaki, H.; Miyagi, A.; Kawai-Yamada, M.; Yamawo, A.

10.1101/2021.07.30.454541 — ecology — Posted on 2021-07-31

16 Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc

Matsuda, S.; Schaefer, J. V.; Mii, Y.; Hori, Y.; Bieli, D.; Taira, M.; Plueckthun, A.; Affolter, M.

10.1101/2020.11.23.394379 — developmental biology — Posted on 2021-07-31

17 Multisite phosphorylation by Cdk1 initiates delayed negative feedback to control mitotic transcription

Asfaha, J.; Ord, M.; Carlson, C.; Faustova, I.; Loog, M.; Morgan, D. O.

10.1101/2021.02.14.431158 — cell biology — Posted on 2021-07-31

18 A unified evolutionary origin for the ubiquitous protein transporters SecY and YidC

Lewis, A. J. O.; Hegde, R. S.

10.1101/2020.12.20.422553 — molecular biology — Posted on 2021-07-31

19 Synaptic plasticity regulated by phosphorylation of PSD-95 Serine 73 in dorsal CA1 is required for contextual fear extinction

Ziolkowska, M.; Borczyk, M.; Nowacka, A.; Nalberczak-Skora, M.; Sliwinska, M. A.; Robacha, M.; Lukasiewicz, K.; Caly, A.; Skonieczna, E.; Tomaszewski, K. F.; Wojtowicz, T.; Wlodarczyk, J.; Bernas, T.; Salamian, A.; Radwanska, K.

10.1101/2020.11.13.381368 — neuroscience — Posted on 2021-07-31

20 Two distinct networks containing position-tolerant representations of actions in the human brain

Yargholi, E.; Hossein-Zadeh, G.-A.; Vaziri-Pashkam, M.

10.1101/2021.06.17.448825 — neuroscience — Posted on 2021-07-31

21 A single nucleotide change in the polC DNA polymerase III in Clostridium thermocellum is sufficient to create a hypermutator phenotype

Lanahan, A. A.; Zakowicz, K.; Tian, L.; Olson, D. G.; Lynd, L. R.

10.1101/2021.07.30.454558 — bioengineering — Posted on 2021-07-31

22 Histone H1 prevents non-CG methylation-mediated small RNA biogenesis in Arabidopsis heterochromatin

Choi, J.; Lyons, D. B.; Zilberman, D.

10.1101/2021.07.31.454434 — genomics — Posted on 2021-07-31

23 Unique signals of clinal and seasonal allele frequency change at eQTLs in Drosophila melanogaster

Yu, Y.; Bergland, A. O.

10.1101/2021.07.30.454552 — evolutionary biology — Posted on 2021-07-31

24 Ecological specialization, rather than the island rule, explains morphological diversification in an ancient radiation of geckos

Tejero-Cicuendez, H.; Simo-Riudalbas, M.; Menendez, I.; Carranza, S.

10.1101/2021.07.30.454424 — evolutionary biology — Posted on 2021-07-31

25 Species hybridisation and clonal expansion as a new fungicide resistance evolutionary mechanism in Pyrenophora teres spp.

Turo, C. J.; Mair, W. J.; Martin, A.; Ellwood, S. R.; Oliver, R.; Lopez-Ruiz, F. J.

10.1101/2021.07.30.454422 — evolutionary biology — Posted on 2021-07-31

26 A pore-forming protein drives macropinocytosis to facilitate toad water maintaining

Zhao, Z.; Shi, Z.; Ye, C.; Zhang, Y.

10.1101/2021.07.31.454564 — cell biology — Posted on 2021-07-31

27 Development of an efficient single-cell cloning and expansion strategy for genome edited induced pluripotent stem cells

Bhargava, N.; Thakur, P.; Muruganandam, T. P.; Jaitly, S.; Gupta, P.; Lohani, N.; Goswami, S. G.; Bhattacharya, S. K.; Jain, S.; Ramalingam, S.

10.1101/2021.07.31.453934 — cell biology — Posted on 2021-07-31

28 FACT maintains pluripotency factor expression through gene-distal regulation in embryonic stem cells

Klein, D. C.; Lardo, S. M.; Hainer, S. J.

10.1101/2021.07.30.454509 — molecular biology — Posted on 2021-07-31

29 Xenotransplantation of porcine progenitor cells in an epileptic California sea lion (Zalophus californianus)

Simeone, C. A.; Andrews, J. P.; Johnson, S. P.; Casalia, M.; Kochanski, R.; Chang, E. F.; Cameron, D.; Dennison, S.; Inglis, B.; Scott, G.; Kruse-Elliott, K.; Okonski, F. F.; Calvo, E.; Goulet, K.; Robles, D.; Griffin-Stence, A.; Kuiper, E.; Krasovec, L.; Field, C. L.; Hoard, V. F.; Baraban, S. C.

10.1101/2021.07.30.454497 — neuroscience — Posted on 2021-07-31

30 Circadian Proteins Cry and Rev-erb Deepen Cellular Quiescence by Down-regulating Cyclin D and Cdk4,6

Wang, X.; Liu, B.; Pan, Q.; Kwon, J. S.; Miller, M. A.; Croce, K. D.; Yao, G.

10.1101/2021.07.30.454549 — systems biology — Posted on 2021-07-31

31 Exploring the miRNA-mediated response to combined stresses in melon plants

Villalba-Bermell, P.; Marquez-Molins, J.; Marques, M.-C.; Hernandez-Azurdia, A.; Corell-Sierra, J.; Pico, B.; Monforte, A. J.; Elena, S. F.; Gomez, G.

10.1101/2021.07.30.454429 — plant biology — Posted on 2021-07-31

32 Emergence of distinct and heterogeneous strains of amyloid beta as Alzheimer s disease progresses in Down syndrome

Maxwell, A. M.; Yuan, P.; Rivera, B. M.; Schaaf, W.; Mladinov, M.; Prasher, V. P.; Robinson, A. C.; DeGrado, W. F.; Condello, C.

10.1101/2021.07.30.454527 — pathology — Posted on 2021-07-31

33 Length Biases in Single-Cell RNA Sequencing of pre-mRNA

Gorin, G.; Pachter, L.

10.1101/2021.07.30.454514 — biophysics — Posted on 2021-07-31

34 Close agreement between deterministic vs. stochastic modeling of first-passage time to vesicle fusion

Matveev, V. V.

10.1101/2021.07.30.454536 — biophysics — Posted on 2021-07-31

35 Assessment of label-free quantification and missing value imputation for proteomics in non-human primates

Hamid, Z.; Zimmerman, K. D.; Guillen-Ahlers, H.; Li, C.; Nathanielsz, P.; Cox, L. A.; Olivier, M.

10.1101/2021.07.30.454221 — genomics — Posted on 2021-07-31

36 Uncovering perturbations in human hematopoiesis associated with healthy aging and myeloid malignancies at single cell resolution

Ainciburu, M.; Ezponda, T.; Berastegui, N.; Alfonso-Pierola, A.; Vilas-Zornoza, A.; San Martin-Uriz, P.; Alignani, D.; Lamo de Espinosa, J.; San Julian, M.; Jimenez, T.; Lopez, F.; Muntion, S.; Sanchez-Guijo, F.; Molero, A.; Montoro, J.; Serrano, G.; Diaz-Mazkiaran, A.; Lasaga, M.; Gomez-Cabrero, D.; Diez-Campelo, M.; Valcarcel, D.; Hernaez, M.; Romero, J. P.; Prosper, F.

10.1101/2021.07.30.454542 — genomics — Posted on 2021-07-31

37 Human gene function publications that describe wrongly identified nucleotide sequence reagents are unacceptably frequent within the genetics literature

Park, Y.; West, R. A.; Pathmendra, P.; Favier, B.; Stoeger, T.; Capes-Davis, A.; Cabanac, G.; Labbe, C.; Byrne, J. A.

10.1101/2021.07.29.453321 — genetics — Posted on 2021-07-31

38 Telmisartan restricts Chikungunya virus infection in vitro and in vivo through the AT1/ PPAR-γ/MAPKs pathways

De, S.; Mamidi, P.; Ghosh, S.; Keshry, S. S.; Mahish, C.; Pani, S. S.; Laha, E.; Ray, A.; Datey, A.; Chatterjee, S.; Singh, S.; Mukherjee, T.; Khamaru, S.; Chattopadhyay, S.; Subudhi, B. B.; Chattopadhyay, S.

10.1101/2021.07.30.454559 — microbiology — Posted on 2021-07-31

39 Engineering adoptive T cell therapy to co-opt Fas ligand-mediated death signaling in ovarian cancer enhances therapeutic efficacy

Anderson, K. G.; Oda, S. K.; Bates, B. M.; Burnett, M. G.; Rodgers Suarez, M.; Ruskin, S. L.; Greenberg, P. D.

10.1101/2021.07.30.454539 — immunology — Posted on 2021-07-31

40 Chronic ethanol drinking in non-human primates induces inflammatory cathepsin gene expression in alveolar macrophages accompanied by functional defects

Lewis, S. A.; Doratt, B.; Sureshchandra, S.; Jankeel, A.; Newman, N.; Grant, K. A.; Messaoudi, I.

10.1101/2021.07.30.454528 — immunology — Posted on 2021-07-31

41 Modular Fluorescent Nanoparticle DNA Probes for Detection of Peptides and Proteins

Stawicki, C. M.; Rinker, T. E.; Burns, M.; Tonapi, S. S.; Galimidi, R. P.; Anumala, D.; Robinson, J. K.; Klein, J. S.; Mallick, P.

10.1101/2021.07.30.454524 — bioengineering — Posted on 2021-07-31

42 A fluorescent sensor for the real-time measurement of extracellular oxytocin dynamics in the brain

Ino, D.; Hibino, H.; Nishiyama, M.

10.1101/2021.07.30.454450 — neuroscience — Posted on 2021-07-31

43 Social selectivity and social motivation in voles

Beery, A. K.; Lopez, S. A.; Blandino, K. L.; Lee, N. S.; Bourdon, N. S.; Ahern, T. H.

10.1101/2021.07.30.454556 — neuroscience — Posted on 2021-07-31

44 Surface Electromyography for Identification of Pre-Phonatory Activity

Kothare, H.; Courey, M. S.; Yung, K. C.; Schneider, S. L.; Nagarajan, S.; Houde, J.

10.1101/2021.07.29.454386 — physiology — Posted on 2021-07-31

45 Molecular dissection of Carbapenem-resistant Acinetobacter baumannii circulating in Indian hospitals usingWhole Genome Sequencing

Rose, S.; Shamanna, V.; Underwood, A.; Nagaraj, G.; Prasanna, A.; Govindan, V.; Darmavaram, S.; M R, S.; Argimon, S.; A, M.; Aanensen, D.; K L, R.

10.1101/2021.07.30.454432 — genomics — Posted on 2021-07-31

46 The dopamine dip amplitude is a quantitative measure of disappointment

Shikano, Y.; Yagishita, S.; Tanaka, K. F.; Takata, N.

10.1101/2021.07.23.453499 — neuroscience — Posted on 2021-07-31

47 Deficiency of the ywhaz gene, involved in neurodevelopmental disorders, alters brain activity and behaviour in zebrafish

Anton-Galindo, E.; Dalla Vecchia, E.; Orlandi, J. G.; Castro, G.; Gualda, E.; Young, A. M.; Aguado, F.; Loza-Alvarez, P.; Cormand, B.; Norton, W. H.; Fernandez-Castillo, N.

10.1101/2021.06.30.450513 — neuroscience — Posted on 2021-07-31

48 Structure Can Predict Function in the Human Brain: A Graph Neural Network Deep Learning Model of Functional Connectivity and Centrality Based on Structural Connectivity

Neudorf, J.; Kress, S.; Borowsky, R.

10.1101/2021.03.15.435531 — neuroscience — Posted on 2021-07-31

49 The olfactory gating of visual preferences to human skin and colors in mosquitoes

Alonso San Alberto, D.; Rusch, C.; Zhan, Y.; Straw, A. D.; Montell, C.; Riffell, J. A.

10.1101/2021.07.26.453916 — neuroscience — Posted on 2021-07-31

50 Modeling the mechanics of growing epithelia with a bilayer plate theory

Ackermann, J.; Qu, P.-Q.; LeGoff, L.; Ben Amar, M.

10.1101/2021.07.30.454446 — biophysics — Posted on 2021-07-31

51 Two step aggregation kinetics of Amyloid-β proteins from fractal analysis

Mukhopadhyay, S.; Bera, S. C.; Ramola, K.

10.1101/2021.07.30.454448 — biophysics — Posted on 2021-07-31

52 Shaping sustainable harvest boundaries for marine populations despite estimation bias

Goto, D.; Devine, J.; Umar, I.; Fischer, S.; De Oliveira, J.; Howell, D.; Jardim, E.; Mosqueira, I.; Ono, K.

10.1101/2020.12.05.413070 — ecology — Posted on 2021-07-31

53 Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development

Mead, T. J.; Martin, D. R.; Wang, L. W.; Cain, S. A.; Gulec, C.; Cahill, E.; Mauch, J.; Reinhardt, D. P.; Lo, C. W.; Baldock, C.; APTE, S.

10.1101/2021.02.03.429587 — developmental biology — Posted on 2021-07-31

54 NAD+ repletion by the PARP inhibitor PJ34 prevents Sarm1 activation and rotenone-induced cell death

Sarkar, A.; Sur, M.; Dey, P.; Mukherjee, P.

10.1101/2021.07.30.454548 — cell biology — Posted on 2021-07-31

55 Tissue-specific heteroplasmy dynamics is accompanied by a sharp drop in mtDNA copy number during development

Tsyba, N.; Patel, M. R.

10.1101/2021.07.30.454495 — cell biology — Posted on 2021-07-31

56 Structural basis for the therapeutic advantage of dual and triple agonists at the human GIP, GLP-1 or GCG receptors

Zhao, F.; Zhou, Q.; Cong, Z.; Hang, K.; Zou, X.; Zhang, C.; Chen, Y.; Dai, A.; Liang, A.; Ming, Q.; Wang, M.; Chen, L.; Xu, P.; Chang, R.; Feng, W.; Xia, T.; Zhang, Y.; Wu, B.; Yang, D.; Zhao, L.; Xu, H. E.; Wang, M.-W.

10.1101/2021.07.29.454286 — molecular biology — Posted on 2021-07-31

57 Multi-tier mechanics control stromal adaptations in swelling lymph nodes

Assen, F. P.; Hons, M.; Hauschild, R.; Shamipour, S.; Abe, J.; Kaufmann, W. A.; Costanzo, T.; Krens, G.; Brown, M.; Ludewig, B.; Hippenmeyer, S.; Stein, J. V.; Heisenberg, C.-P.; Hannezo, E.; Luther, S. A.; Sixt, M.

10.1101/2021.07.28.454217 — immunology — Posted on 2021-07-31

58 Value, confidence and deliberation: a functional partition of the medial prefrontal cortex across preference tasks

Clairis, N.; Pessiglione, M.

10.1101/2020.09.17.301291 — neuroscience — Posted on 2021-07-31

59 Developmental change in prefrontal cortex recruitment supports the emergence of value-guided memory

Nussenbaum, K.; Hartley, C. A.

10.1101/2021.02.13.431073 — neuroscience — Posted on 2021-07-31

60 The heart rate discrimination task: a psychophysical method to estimate the accuracy and precision of interoceptive beliefs

Legrand, N.; Nikolova, N.; Correa, C.; Braendholt, M.; Stuckert, A.; Kildahl, N.; Vejlo, M.; Fardo, F.; Allen, M.

10.1101/2021.02.18.431871 — neuroscience — Posted on 2021-07-31

61 Amazonian run-of-river dam reservoir impacts underestimated: Evidence from a Before-After Control-Impact study of freshwater turtle nesting areas

Barcenas-Garcia, A.; Michalski, F.; Gibbs, J. P.; Norris, D.

10.1101/2021.07.29.454366 — zoology — Posted on 2021-07-31

62 Framework to simulate gene regulatory networks with stochastic molecular kinetics and to infer steady-state network structure

Hettich, J.; Gebhardt, J. C. M.

10.1101/872374 — systems biology — Posted on 2021-07-31

63 A Novel Proposal for an Index for Regional Cerebral Perfusion Pressure - A Theoretical Approach Using Fluid Dynamics

Kameyama, M.; Momose, T.

10.1101/2021.07.18.452866 — physiology — Posted on 2021-07-31

64 Mitochondrial TRAK adaptors coordinate dynein and kinesin motility

Canty, J. T.; Hensley, A.; Yildiz, A.

10.1101/2021.07.30.454553 — biophysics — Posted on 2021-07-31

65 Quantitative Single-Molecule Imaging with Statistical Machine Learning

Boonkird, A.; Nino, D. F.; Milstein, J. N.

10.1101/2021.07.30.454455 — biophysics — Posted on 2021-07-31

66 Phenotyping of Klf14 mouse white adipose tissue enabled by whole slide segmentation with deep neural networks

Casero, R.; Westerberg, H.; Horner, N. R.; Yon, M.; Aberdeen, A.; Grau, V.; Cox, R. D.; Rittscher, J.; Mallon, A.-M.

10.1101/2021.06.03.444997 — bioinformatics — Posted on 2021-07-30

67 Discovering molecular features of intrinsically disordered regions by using evolution for contrastive learning

Lu, A. X.; Lu, A. X.; Pritisanac, I.; Zarin, T.; Forman-Kay, J. D.; Moses, A. M.

10.1101/2021.07.29.454330 — bioinformatics — Posted on 2021-07-31

68 Relationship between shear wave velocity and muscle activation is inconsistent across different muscle types

Bernabei, M.; Ludvig, D.; Sandercock, T. G.; Perreault, E. J.; Lee, S. S. M.

10.1101/2021.04.07.438761 — bioengineering — Posted on 2021-07-31

69 Intrinsically disordered N-terminal domain (NTD) of p53 interacts with mitochondrial PTP regulator Cyclophilin D

Zhao, J.; Liu, X.; Blayney, A.; Zhang, Y.; Gandy, L.; Zhang, F.; Linhardt, R. J.; Chen, J.; Baines, C.; Loh, S. N.; Wang, C.

10.1101/2021.07.23.453429 — biochemistry — Posted on 2021-07-30

70 The mechanism of MinD stability modulation by MinE in Min protein dynamics

Carlquist, W. C.; Cytrynbaum, E. N.

10.1101/2021.07.30.454523 — biochemistry — Posted on 2021-07-31

71 NHR-8 regulated P-glycoproteins uncouple xenobiotic stress resistance from longevity in chemosensory C. elegans mutants

Guerrero, G. A.; Derisbourg, M. J.; Wester, L. E.; Giorda, M.; Dinort, J. E.; Alonso, M. J.; Hartman, M. D.; Schilling, K.; Mayr, F. A. M. C.; Lu, R.; Benayoun, B. A.; Denzel, M. S.

10.1101/823302 — genetics — Posted on 2021-07-30

72 Inference of recent admixture using genotype data

Pfaffelhuber, P.; Sester-Huss, E.; Baumdicker, F.; Naue, J.; Lutz-Bonengel, S.; Staubach, F.

10.1101/2020.09.16.300640 — genetics — Posted on 2021-07-31

73 The role of muscle stem cells and fibro-adipogenic progenitors in female pelvic floor muscle regeneration following birth injury

Boscolo Sesillo, F.; Rajesh, V.; Wong, M.; Duran, P.; Baynes, B.; Laurent, L. C.; Christman, K.; Sacco, A.; Alperin, M.

10.1101/2021.07.30.454534 — cell biology — Posted on 2021-07-31

74 Production of human translation-competent lysates using dual centrifugation

Gurzeler, L.-A.; Ziegelmuller, J.; Muhlemann, O.; Karousis, E. D.

10.1101/2021.05.27.445927 — molecular biology — Posted on 2021-07-30

75 Genome assemblies across the diverse evolutionary spectrum of Leishmania protozoan parasites

Warren, W. C.; Akopyants, N.; Dobson, D. E.; Hertz-Fowler, C.; Lye, L.-F.; Myler, P. J.; Ramasamy, G.; Shanmugasundram, A.; Silva-Franco, F.; Steinbiss, S.; Tomlinson, C.; Wilson, R. K.; Beverley, S. M.

10.1101/2021.05.29.446295 — microbiology — Posted on 2021-07-30

76 Tissue homeostasis and adaptation to immune challenge resolved by fibroblast network mechanics

Horsnell, H. L.; Tetley, R. J.; de Belly, H.; Makris, S.; Benjamin, A. C.; Paluch, E.; Mao, Y.; Acton, S. E.

10.1101/2021.05.27.446027 — immunology — Posted on 2021-07-30

77 Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at Chr16q11.2 and on the MAPT H1 allele

Soutar, M.; Melandri, D.; O'Callaghan, B.; Annuario, E.; Monaghan, A.; Welsh, N.; D'Sa, K.; Guelfi, S.; Zhang, D.; Pittman, A.; Trabzuni, D.; Pan, K.; Kia, D. A.; Bictash, M.; Gandhi, S.; Houlden, H.; Cookson, M. R.; Wood, N.; Singleton, A.; Hardy, J.; Whiting, P.; Blauwendraat, C.; Whitworth, A.; Manzoni, C.; Ryten, M.; Lewis, P.; Plun-Favreau, H.

10.1101/2020.01.06.896241 — neuroscience — Posted on 2021-07-30

78 Contextual effects in motor adaptation adhere to associative learning rules

Avraham, G.; Taylor, J. A.; Breska, A.; Ivry, R. B.; McDougle, S. D.

10.1101/2020.09.14.297143 — neuroscience — Posted on 2021-07-30

79 Identifying sub-populations of cells in single cell transcriptomic data - a Bayesian mixture model approach to zero-inflation of counts

Wilson, T.; Thorne, T.

10.1101/2021.05.19.444841 — systems biology — Posted on 2021-07-30

80 Identification of an isoflavonoid transporter required for the nodule establishment of the Rhizobium-Fabaceae symbiotic interaction

Biala-Leonhard, W.; Zanin, L.; Gottardi, S.; de Brito Francisco, R.; Venuti, S.; Valentinuzzi, F.; Mimmo, T.; Cesco, S.; Bassin, B.; Martinoia, E.; Pinton, R.; Jasinski, M.; Tomasi, N.

10.1101/2021.07.30.452494 — plant biology — Posted on 2021-07-30

81 HGFAC is a ChREBP Regulated Hepatokine that Enhances Glucose and Lipid Homeostasis

Sargsyan, A.; Doridot, L.; Hannou, S. A.; Tong, W.; Srinivasan, H.; Ivison, R.; Monn, R.; Kou, H. H.; Haldeman, J. M.; Arlotto, M.; White, P. J.; Grimsrud, P. A.; Astapova, I.; Tsai, L.; Herman, M. A.

10.1101/2021.07.29.454308 — physiology — Posted on 2021-07-30

82 Accurate recognition of colorectal cancer with semi-supervised deep learning on pathological images

Yu, G.; Xie, T.; Xu, C.; Shi, X.-H.; Wu, C.; Sun, K.; Meng, R.-Q.; Meng, X.-H.; Wang, K.-S.; Xiao, H.-M.; Deng, H.-W.

10.1101/2020.07.13.201582 — pathology — Posted on 2021-07-30

83 ZIP9 is a Druggable Determinant of Sex Differences in Melanoma

Aguirre-Portoles, C.; Payne, R.; Trautz, A.; Foskett, J. K.; Natale, C. A.; Seykora, J. T.; Ridky, T. W.

10.1101/2020.03.12.989160 — cancer biology — Posted on 2021-07-30

84 Human papillomavirus type 16 sub-lineages and integration in cancer

Jackson, R.; Ortigas-Vasquez, A.; Zehbe, I.

10.1101/2020.06.25.162958 — cancer biology — Posted on 2021-07-30

85 Natural isotope correction improves analysis of protein modification dynamics

Dietze, J.; van Pijkeren, A.; Egger, A.-S.; Ziegler, M.; Kwiatkowski, M.; Heiland, I.

10.1101/2020.10.31.361725 — bioinformatics — Posted on 2021-07-30

86 Probing T-cell response by sequence-based probabilistic modeling

Bravi, B.; Balachandran, V. P.; Greenbaum, B. D.; Walczak, A. M.; Mora, T.; Monasson, R.; Cocco, S.

10.1101/2020.12.17.423283 — bioinformatics — Posted on 2021-07-30

87 Kincore: a web resource for structural classification of protein kinases and their inhibitors

Modi, V.; Dunbrack, R.

10.1101/2021.02.12.430923 — bioinformatics — Posted on 2021-07-30

88 Regulatory network-based imputation of dropouts in single-cell RNA sequencing data

Leote, A. C.; Wu, X.; Beyer, A.

10.1101/611517 — bioinformatics — Posted on 2021-07-30

89 Classification of the plant-associated phenotype of Pseudomonas strains using genome properties and machine learning

Poncheewin, W.; van Diepeningen, A. D.; van der Lee, T. A.; Suarez-Diez, M.; Schaap, P. J.

10.1101/2021.07.30.454435 — genomics — Posted on 2021-07-30

90 Generation of a new six1-null line in Xenopus tropicalis for study of development and congenital disease

Coppenrath, K.; Tavares, A. L. P.; Shaidani, N.-I.; Wlizla, M.; Moody, S. A.; Horb, M.

10.1101/2021.07.30.454496 — developmental biology — Posted on 2021-07-30

91 Identification of the Global miR-130a Targetome Reveals a Novel Role for TBL1XR1 in Hematopoietic Stem Cell Self-Renewal and t(8;21) AML

Krivdova, G.; Voisin, V.; Schoof, E. M.; Marhon, S. A.; Murison, A. J.; McLeod, J. L.; Gabra, M.; Zeng, A. G.; Van Nostrand, E. L.; Aigner, S. J.; Shishkin, A. A.; Yee, B. A.; Hermans, K. G.; Trotman-Grant, A. G.; Mbong, N.; Kennedy, J. A.; Gan, O. I.; Wagenblast, E.; De Carvalho, D. D.; LAB, S.; Minden, M. D.; Bader, G. D.; Yeo, G. W.; Dick, J. E.; Lechman, E. R.

10.1101/2021.07.30.454489 — cell biology — Posted on 2021-07-30

92 Highly efficient SARS-CoV-2 infection of human cardiomyocytes: spike protein-mediated cell fusion and its inhibition

Navaratnarajah, C. K.; Pease, D. R.; Halfmann, P.; Taye, B.; Barkhymer, A.; Howell, K. G.; Charlesworth, J. E.; Christensen, T. A.; Kawaoka, Y.; Cattaneo, R.; Schneider, J. W.; Timothy J. Nelson (Director), Boyd Rasmussen and Frank J. Secreto,

10.1101/2021.07.30.454437 — microbiology — Posted on 2021-07-30

93 Evolution of protection after maternal immunization for respiratory syncytial virus in cotton rats

Blanco, J. C. G.; McGinnes-Cullen, L.; Kamali, A.; Sylla, F.; Boukhavalova, M.; Morrison, T.

10.1101/2021.07.30.454440 — microbiology — Posted on 2021-07-30

94 Smallpox vaccination induces a substantial increase in commensal skin bacteria that promote pathology and enhance immunity

Shmeleva, E. V.; Gomez de Agüero, M.; Wagner, J.; Enright, A. J.; Macpherson, A. J.; Ferguson, B. J.; Smith, G. L.

10.1101/2021.07.30.454438 — microbiology — Posted on 2021-07-30

95 Collagen (I) homotrimer potentiates the osteogenesis imperfecta (oim) mutant allele and reduces survival in male mice

Lee, K. J.; Rambault, L.; Bou-Gharios, G.; Clegg, P. D.; Akhtar, R.; Czanner, G.; van 't Hof, R. J.; Canty-Laird, E. G.

10.1101/2020.07.13.198283 — physiology — Posted on 2021-07-30

96 Doxycycline inhibition of a pseudotyped virus transduction does not translate to inhibition of SARS-CoV-2 infectivity

Diomede, L.; Baroni, S.; De Luigi, A.; Piotti, A.; Lucchetti, J.; Fracasso, C.; Russo, L.; Bonaldo, V.; Panini, N.; Filippini, F.; Fiordaliso, F.; Corbelli, A.; Beeg, M.; Pizzato, M.; Caccuri, F.; Gobbi, M.; Biasini, E.; Caruso, A.; Salmona, M.

10.1101/2021.07.30.454436 — pharmacology and toxicology — Posted on 2021-07-30

97 Anaplerotic flux into the Calvin-Benson cycle. Isotope evidence for in vivo occurrence in Helianthus annuus

Wieloch, T.; Augusti, A.; Schleucher, J.

10.1101/2021.07.30.454453 — biophysics — Posted on 2021-07-30

98 Mitotic Chromosome Condensation Driven by a Volume Phase Transition

Beel, A. J.; Matteï, P.-J.; Kornberg, R. D.

10.1101/2021.07.30.454418 — biophysics — Posted on 2021-07-30

99 Phosphoproteomic analysis of chondrocytes after short-term exposure to inorganic polyphosphate

Kuzmanov, U.; Gawri, R.; Zelinka, A.; Russel, K. A.; Lee, S.-H.; Gramolini, A. O.; Kandel, R.

10.1101/2021.07.30.454470 — bioengineering — Posted on 2021-07-30

100 Directed biosynthesis of fluorinated polyketides

Rittner, A.; Joppe, M.; Schmidt, J. J.; Mayer, L. M.; Heid, E.; Sherman, D. H.; Grininger, M.

10.1101/2021.07.30.454469 — biochemistry — Posted on 2021-07-30

101 Molecular dissection of Carbapenem-resistant Acinetobacter baumannii circulating in Indian hospitals usingWhole Genome Sequencing

Rose, S.; Shamanna, V.; Underwood, A.; Nagaraj, G.; Prasanna, A.; Govindan, V.; Darmavaram, S.; M R, S.; Argimon, S.; A, M.; Aanensen, D.; K L, R.

10.1101/2021.07.30.454432 — genomics — Posted on 2021-07-30

102 Epigenetic Divergence during Early Stages of Speciation in an African Crater Lake Cichlid Fish

Vernaz, G.; Hudson, A. G.; Santos, M. E.; Fischer, B.; Carruthers, M.; Shechonge, A. H.; Gabagambi, N. P.; Tyers, A. M.; Ngatunga, B. P.; Malinsky, M.; Durbin, R.; Turner, G. F.; Genner, M. J.; Miska, E. A.

10.1101/2021.07.30.435319 — genomics — Posted on 2021-07-30

103 The genetic origin of Daunians and the Pan-Mediterranean southern Italian Iron Age context

Aneli, S.; Saupe, T.; Montinaro, F.; Solnik, A.; Molinaro, L.; Scaggion, C.; Carrara, N.; Raveane, A.; Kivisild, T.; Metspalu, M.; Scheib, C. L.; Pagani, L.

10.1101/2021.07.30.454498 — genetics — Posted on 2021-07-30

104 Role of glutathione on cell adhesion and volume.

Geloen, A.; Danty, E.

10.1101/2021.07.30.454460 — cell biology — Posted on 2021-07-30

105 Localization of infection in neonatal rhesus macaques after oral viral challenge

Hope, T. J.; Taylor, R. A.; McRaven, M. D.; Carias, A. M.; Anderson, M. R.; Matias, E.; Arainga, M.; Allen, E. J.; Rogers, K. A.; Gupta, S.; Kulkarni, V.; Lakhashe, S.; Lorenzo-Redondo, R.; Thomas, Y.; Strickland, A.; Villinger, F. J.; Ruprecht, R. M.

10.1101/2021.07.30.454439 — cell biology — Posted on 2021-07-30

106 A new paradigm for leprosy diagnosis based on host gene expression

Leal-Calvo, T.; Avanzi, C.; Mendes, M. A.; Benjak, A.; Busso, P.; Pinheiro, R. O.; Sarno, E. N.; Cole, S. T.; Moraes, M. O.

10.1101/2021.07.30.454441 — molecular biology — Posted on 2021-07-30

107 Identification and functional characterization of transcriptional activators in human cells

Alerasool, N.; Lin, Z.-Y.; Gingras, A.-C.; Taipale, M.

10.1101/2021.07.30.454360 — molecular biology — Posted on 2021-07-30

108 Genomic and chemical decryption of the Bacteroidetes phylum for its potential to biosynthesize natural products

Brinkmann, S.; Kurz, M.; Patras, M. A.; Hartwig, C.; Marner, M.; Leis, B.; Billion, A.; Kleiner, Y.; Bauer, A.; Toti, L.; Poeverlein, C.; Hammann, P. E.; Vilcinskas, A.; Glaeser, J.; Spohn, M. S.; Schaeberle, T. F.

10.1101/2021.07.30.454449 — microbiology — Posted on 2021-07-30

109 Mechanism of Antiviral Activity of Nitazoxanide against the Influenza Virus: Effect of Tizoxanide on AdenosineTriphosphate in Influenza-virus Infected Madin Darby Canine Kidney Cells

Rossignol, J.-F.; Baalen, C. v.; Tijsma, A.

10.1101/2021.07.30.454324 — microbiology — Posted on 2021-07-30

110 Roscovitine exacerbates Mycobacterium abscessus infection by reducing NADPH oxidase-dependent neutrophil trafficking

Le Moigne, V.; Rodriguez Rincon, D.; Glatigny, S.; Dupont, C.; Langevin, C.; Ait Ali Said, A.; Renshaw, S. A.; Floto, A. R.; Herrmann, J.-L.; Bernut, A.

10.1101/2021.07.30.454490 — microbiology — Posted on 2021-07-30

111 Atp{Theta} is an inhibitor of F0F1 ATP synthase to arrest ATP hydrolysis during low-energy conditions in cyanobacteria

Song, K.; Baumgartner, D.; Hagemann, M.; Muro-Pastor, A. M.; Maass, S.; Becher, D.; Hess, W. R.

10.1101/2021.07.30.454416 — microbiology — Posted on 2021-07-30

112 The effects of a synthetic and biological surfactant on the community composition and metabolic activity of a freshwater biofilm

Gill, S.; Hunter, W.; Coulson, L.; Schelker, J.

10.1101/2021.07.30.454494 — microbiology — Posted on 2021-07-30

113 CD49a Identifies Polyfunctional Memory CD8 T cell Subsets that Persist in the Lungs after Influenza Infection

Reilly, E. C.; Sportiello, M.; Lambert Emo, K.; Amitrano, A. M.; Jha, R.; Kumar, A. B.; Laniewski, N. G.; Yang, H.; Kim, M.; Topham, D. J.

10.1101/2021.07.30.454373 — immunology — Posted on 2021-07-30

114 Regeneration of humoral immunity from pluripotent stem cells by defined transcription factors

Zhang, Q.; Wu, B.; Weng, Q.; Hu, F.; Lin, Y.; Xia, C.; Peng, H.; Wang, Y.; Liu, X.; Liu, L.; Xiong, J.; Geng, Y.; Zhao, Y.; Zhang, M.; Du, J.; Wang, J.

10.1101/2021.07.30.454442 — immunology — Posted on 2021-07-30

115 Activation of M1 muscarinic receptors reduce pathology and slow progression of neurodegenerative disease.

Dwomoh, L.; Rossi, M.; Scarpa, M.; Khajehali, E.; Molloy, C.; Herzyk, P.; Mistry, S. N.; Bottrill, A.; Sexton, P. M.; Christopoulos, A.; Conn, J. P.; Lindsley, C. W.; Bradley, S. J.; Tobin, A. B.

10.1101/2021.07.30.454298 — neuroscience — Posted on 2021-07-30

116 PROTECTIVE ROLE FOR SMOOTH MUSCLE CELL HEPCIDIN IN ABDOMINAL AORTIC ANEURYSM

Loick, P.; Mohammad, G.; Cassinmjee, I.; Chandrashekar, A.; Lapolla, P.; Carrington, A.; Handa, A.; Lee, R.; Lakhal-Littleton, S.

10.1101/2021.07.30.454447 — physiology — Posted on 2021-07-30

117 PERK inhibition blocks metastasis initiation by limiting UPR-dependent survival of dormant disseminated cancer cells

Calvo, V.; Zheng, W.; Staschke, K. A.; Nobre, A. R.; Farias, E. F.; Nowacek, A.; Mulvihill, M.; Rigby, A. C.; Aguirre-Ghiso, J. A.

10.1101/2021.07.30.454473 — cancer biology — Posted on 2021-07-30

118 Development of a compact alkynyl-enrichable crosslinker for in-depth in-vivo crosslinking analysis

Gao, H.; Zhao, L. L.; Zhao, Q.; Zhang, H. L.; Zhao, F. B.; Gong, Z.

10.1101/2021.07.30.454285 — biochemistry — Posted on 2021-07-30

119 Lipid flippase dysfunction as a novel therapeutic target for endosomal anomalies in Alzheimer's disease

KANESHIRO, N.; MASATO, K.; IMAOKA, R.; IKEDA, A.; KAMIKUBO, Y.; HASHIMOTO, T.; IWATSUBO, T.; SAKURAI, T.; UEHARA, T.; TAKASUGI, N.

10.1101/2021.07.30.454423 — biochemistry — Posted on 2021-07-30

120 COVID-ONE-humoral immune: The One-stop Database for COVID-19-specific Antibody Responses and Clinical Parameters

Xu, Z.; Li, Y.; Lei, Q.; Huang, L.; Lai, D.-y.; Guo, S.-j.; Jiang, H.-w.; Hou, H.; Zheng, Y.-x.; Wang, X.-n.; Wu, J.; Ma, M.-l.; Zhang, B.; Chen, H.; Yu, C.; Xue, J.-b.; Zhang, H.-n.; Qi, H.; Yu, S.; Lin, M.; Zhang, Y.; Lin, X.; Yao, Z.; Sheng, H.; Sun, Z.; Wang, F.; Fan, X.; Tao, S.-c.

10.1101/2021.07.29.454261 — microbiology — Posted on 2021-07-30

121 SARS-CoV-2 introduction and lineage dynamics across three epidemic peaks in Southern Brazil: massive spread of P.1

Varela, A. P. M.; Prichula, J.; Meyer, F. Q.; Salvato, R.; Sant'Anna, F. H.; Gregianini, T. S.; Martins, L. G.; Seixas, A.; Veiga, A. B. G. d.

10.1101/2021.07.29.454323 — genomics — Posted on 2021-07-30

122 Structural basis for the therapeutic advantage of dual and triple agonists at the human GIP, GLP-1 or GCG receptors

10.1101/2021.07.29.454286 — molecular biology — Posted on 2021-07-30

123 Mice with High FGF21 Serum Levels Had a Reduced Preference for Morphine and an Attenuated Development of Acute Antinociceptive Tolerance and Physical Dependence

Dorval, L.; Knapp, B. I.; Majekodunmi, O. A.; Eliseeva, S.; Bidlack, J. M.

10.1101/2021.07.30.453845 — neuroscience — Posted on 2021-07-30

124 Identification and Characterization of novel mutants of Nsp13 Protein among Indian SARS-CoV-2 isolates.

Kumari, D.; Kumari, N.; Kumar, S.; Sinha, P. K.; Shahi, S. K.; Biswas, N. R.; Kumar, A.

10.1101/2021.07.30.454406 — bioinformatics — Posted on 2021-07-30

125 3D printed cobalt-chromium-molybdenum porous superalloy with superior antiviral activity

Arjunan, A.; Robinson, J.; Baroutaji, A.; Marti, M.; Tunon-Molina, A.; Serrano-Aroca, A.

10.1101/2021.07.29.454385 — bioengineering — Posted on 2021-07-30

126 A method for the generation of pseudotyped virus particles bearing SARS coronavirus spike protein in high yields

Fujioka, Y.; Kashiwagi, S.; Yoshida, A.; Satoh, A. O.; Fujioka, M.; Amano, M.; Yamauchi, Y.; Ohba, Y.

10.1101/2021.07.30.454063 — microbiology — Posted on 2021-07-30

127 Photosensitized Electrospun Nanofibrous Filters for Capturing and Killing Airborne Coronaviruses under Visible Light Irradiation

Shen, H.; Zhou, Z.; Wang, H.; Zhang, M.; Han, M.; Shen, Y.; Shuai, D.

10.1101/2021.07.29.454404 — microbiology — Posted on 2021-07-30

128 Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 Synthase Deficiency variants

Dookwah, M.; Wagner, S. K.; Ishihara, M.; Yu, S.-h.; Ulrichs, H.; Kulik, M. J.; Zeltner, N.; Dalton, S.; Strauss, K. A.; Aoki, K.; Steet, R.; Tiemeyer, M.

10.1101/2021.07.29.454399 — neuroscience — Posted on 2021-07-30

129 A semisynthetic glycoconjugate provides expanded cross-serotype protection against Streptococcus pneumoniae

Kaplonek, P. M.; Yao, L.; Reppe, K.; Voss, F. M.; Kohler, T.; Ebner, F.; Schaefer, A.; Blohm, U.; Priegue, P.; Brautigam, M.; Pereira, C. L.; Parameswarappa, S. G.; Emmadi, M.; Menova, P.; Witzenrath, M.; Hammerschmidt, S.; Hartmann, S.; Sander, L. E.; Seeberger, P. H.

10.1101/2021.07.29.454378 — immunology — Posted on 2021-07-30

130 Surface Electromyography for Identification of Pre-Phonatory Activity

Kothare, H.; Courey, M. S.; Yung, K. C.; Schneider, S. L.; Nagarajan, S.; Houde, J.

10.1101/2021.07.29.454386 — physiology — Posted on 2021-07-30

131 miRSCAPE - Inferring miRNA expression in single-cell clusters

Olgun, G.; Gopalan, V.; Hannenhalli, S.

10.1101/2021.07.29.454389 — bioinformatics — Posted on 2021-07-30

132 MOSGA 2: Comparative genomics and validation tools

Martin, R.; Dressler, H.; Hattab, G.; Hackl, T.; Fischer, M. G.; Heider, D.

10.1101/2021.07.29.454382 — bioinformatics — Posted on 2021-07-30

133 Removing the ceiling on droplet microfluidics

Khor, J. W.; Lee, U. N.; Berthier, J.; Berthier, E.; Theberge, A. B.

10.1101/2021.07.29.454194 — bioengineering — Posted on 2021-07-30

134 A small-molecule fluorescent probe for live-cell imaging of endocytosis

Seino, R.; Iwashita, H.; Takahashi, M.; Ezoe, T.; Ishiyama, M.; Ueno, Y.

10.1101/2021.07.29.454398 — biochemistry — Posted on 2021-07-30

135 Habit formation viewed as structural change in the behavioral network

Yamada, K.; Toda, K.

10.1101/2021.07.29.454400 — animal behavior and cognition — Posted on 2021-07-30

136 Non-coding circular RNAs repertoire and expression profile during Brassica rapa pollen development

Babaei, S.; Singh, M. B.; Bhalla, P. L.

10.1101/2021.07.29.454397 — molecular biology — Posted on 2021-07-30

137 Exogenous pigments shield microorganisms from spaceflight-induced changes

Sharma, S.; Smith, R. S. H.; Lee, N. A.; Wilson, S. L.; Smith, M. M.; Oxman, N.

10.1101/2021.07.29.454367 — microbiology — Posted on 2021-07-30

138 The Diguanylate Cyclase YfiN of Pseudomonas aeruginosa Regulates Biofilm Maintenance in Response to Peroxide

Katharios-Lanwermeyer, S.; Koval, S.; Barrack, K.; O'Toole, G.

10.1101/2021.07.29.454409 — microbiology — Posted on 2021-07-30

139 Direct and indirect interactions promote complexes of the lipoprotein LbcA, the CtpA protease and its substrates, and other cell wall proteins in Pseudomonas aeruginosa

Chakraborty, D.; Darwin, A. J.

10.1101/2021.07.29.454410 — microbiology — Posted on 2021-07-30

140 Training a spiking neuronal network model of visual-motor cortex to play a virtual racket-ball game using reinforcement learning

Anwar, H.; Caby, S.; Dura-Bernal, S.; D'Onofrio, D.; Hasegan, D.; Deible, M.; Grunblatt, S.; Chadderdon, G. L.; Kerr, C. C.; Lakatos, P.; Lytton, W. W.; Hazan, H.; Neymotin, S. A.

10.1101/2021.07.29.454361 — neuroscience — Posted on 2021-07-30

141 Large-scale dendritic spine extraction and analysis through petascale computing

Wildenberg, G.; Li, H.; Badalamente, G. A.; Uram, T. D.; Ferrier, N.; Kasthuri, N.

10.1101/2021.07.29.454371 — neuroscience — Posted on 2021-07-30

142 Robust adaptive distance functions for approximate Bayesian inference on outlier-corrupted data

Schaelte, Y.; Alamoudi, E.; Hasenauer, J.

10.1101/2021.07.29.454327 — systems biology — Posted on 2021-07-30

143 Carbon nanotube biocompatibility in plants is determined by their surface chemistry

Gonzalez-Grandio, E.; Demirer, G. S.; Jackson, C. T.; Yang, D.; Landry, M. P.

10.1101/2021.07.29.454380 — plant biology — Posted on 2021-07-30

144 TRPM2 deficiency protects against atherosclerosis by inhibiting TRPM2-CD36 inflammatory axis in macrophages

Zong, P.; Feng, J.; Yue, Z.; Yu, A. S.; Mori, Y.; Yue, L.

10.1101/2021.07.29.454234 — physiology — Posted on 2021-07-30

145 Temporal variation in lymphocyte proteomics

McCown, M. A.; Allen, C.; Machado, D. D.; Boekweg, H.; Liang, Y.; Nwosu, A. J.; Kelly, R. T.; Payne, S. H.

10.1101/2021.07.29.454362 — bioinformatics — Posted on 2021-07-30

146 OperonSEQer: A set of machine-learning algorithms with threshold voting for detection of operon pairs using short-read RNA-sequencing data

Krishnakumar, R.; Ruffing, A. M.

10.1101/2021.07.29.454062 — bioinformatics — Posted on 2021-07-30

147 Discovery of small molecule pathway regulators by image profile matching

Rohban, M. H.; Fuller, A. M.; Tan, C.; Goldstein, J. T.; Syangtan, D.; Gutnick, A.; Nijsure, M. P.; Rigby, M.; Sacher, J. R.; Corsello, S. M.; Peppler, G. B.; Bogaczynska, M.; Ciotti, G. E.; DeVine, A.; Doan, M.; Gale, J. P.; Derynck, R.; Turbyville, T.; Boerckel, J. D.; Singh, S.; Kiessling, L. L.; Schwarz, T. L.; Varelas, X.; Wagner, F. F.; Kafri, R.; Eisinger-Mathason, T. S. K.; Carpenter, A. E.

10.1101/2021.07.29.454377 — bioinformatics — Posted on 2021-07-30

148 Discovering molecular features of intrinsically disordered regions by using evolution for contrastive learning

Lu, A. X.; Lu, A. X.; Pritisanac, I.; Zarin, T.; Forman-Kay, J. D.; Moses, A. M.

10.1101/2021.07.29.454330 — bioinformatics — Posted on 2021-07-30

149 Species-wide phylogenomics of the Staphylococcus aureus agr operon reveals convergent evolution of frameshift mutations

Raghuram, V.; Alexander, A. M.; Loo, H. Q.; Petit, R. A.; Goldberg, J. B.; Read, T. D.

10.1101/2021.07.29.454156 — genomics — Posted on 2021-07-30

150 GCAT dotplots characterize precisely and imprecisely defined topological features of DNA

Collett, J. I.; Pearce, S. R.

10.1101/2021.07.29.454305 — genetics — Posted on 2021-07-30

151 Large herbivorous wildlife and livestock differentially influence the relative importance of different sources of carbon for riverine food webs

Masese, F. O.; Fuss, T.; Bistarelli, L.; Buchen-Tschiskale, C.; Singer, G.

10.1101/2021.07.29.454315 — ecology — Posted on 2021-07-30

152 Sleep spindle dynamics suggest over-consolidation in post-traumatic stress disorder

van der Heijden, A. C.; Hofman, W. F.; de Boer, M.; Nijdam, M. J.; van Marle, H. J.; Jongedijk, R. J.; Olff, M.; Talamini, L. M.

10.1101/2021.07.29.453342 — neuroscience — Posted on 2021-07-30

153 A machine-learning approach for detection of local brain networks and marginally weak signals identifies novel AD/MCI differentiating connectomic neuroimaging biomarkers

Li, Y.; Kang, J.; Wu, C.; Dinov, I.; Hu, j.; Chalise, P.; Mahnken, J.

10.1101/2021.07.29.454368 — neuroscience — Posted on 2021-07-30

154 Amazonian run-of-river dam reservoir impacts underestimated: Evidence from a Before-After Control-Impact study of freshwater turtle nesting areas

Barcenas-Garcia, A.; Michalski, F.; Gibbs, J. P.; Norris, D.

10.1101/2021.07.29.454366 — zoology — Posted on 2021-07-30

155 SMGen: A generator of synthetic models of biochemical reaction networks

Riva, S. G.; Cazzaniga, P.; Nobile, M. S.; Spolaor, S.; Rundo, L.; Besozzi, D.; Tangherloni, A.

10.1101/2021.07.29.454343 — systems biology — Posted on 2021-07-30

156 SimpleForest - a comprehensive tool for 3d reconstruction of trees from forest plot point clouds

Hackenberg, J.; Calders, K.; Demol, M.; Raumonen, P.; Piboule, A.; Disney, M.

10.1101/2021.07.29.454344 — plant biology — Posted on 2021-07-30

157 Artificial Neural Networks for classification of single cell gene expression

Zhong, J.; Lyu, M.; Jin, H.; Cao, Z.; Chitkushev, L. T.; Zhang, G.; Keskin, D. B.; Brusic, V.

10.1101/2021.07.29.454293 — bioinformatics — Posted on 2021-07-30

158 Cholesterol plays a decisive role in tetraspanin assemblies during bilayer deformations

Caparotta, M.; Masone, D.

10.1101/2021.07.29.454363 — bioinformatics — Posted on 2021-07-30

159 Automated Feeding and Fermentation Phase Transitions for the Production of Unspecific Peroxygenase by Pichia pastoris

Hobisch, M.; Kara, S.

10.1101/2021.07.29.454275 — bioengineering — Posted on 2021-07-30

160 AnchorWave: sensitive alignment of genomes with high diversity, structural polymorphism and whole-genome duplication variation

Song, B.; Marco-Sola, S.; Moreto, M.; Johnson, L.; Buckler, E. S.; Stitzer, M. C.

10.1101/2021.07.29.454331 — genomics — Posted on 2021-07-30

161 A Kernel Method for Dissecting Genetic Signals in Tests of High-Dimensional Phenotypes

Solis-Lemus, C.; Holleman, A. M.; Todor, A.; Bradley, B.; Ressler, K. J.; Ghosh, D.; Epstein, M.

10.1101/2021.07.29.454336 — genomics — Posted on 2021-07-30

162 Modeling memory T cell states at single-cell resolution identifies in vivo state-dependence of eQTLs influencing disease

Nathan, A.; Asgari, S.; Ishigaki, K.; Amariuta, T.; Luo, Y.; Beynor, J. I.; Baglaenko, Y.; Suliman, S.; Price, A.; Lecca, L.; Murray, M. B.; Moody, D. B.; Raychaudhuri, S.

10.1101/2021.07.29.454316 — genetics — Posted on 2021-07-30

163 Across-population genomic prediction in grapevine opens up promising prospects for breeding

Brault, C.; Segura, V.; This, P.; Le Cunff, L.; Flutre, T.; Francois, P.; Pons, T.; Peros, J.-P.; Doligez, A.

10.1101/2021.07.29.454290 — genetics — Posted on 2021-07-30

164 Plant-associate interactions and diversification across trophic levels

Yoder, J. B.; Dang, A.; MacGregor, C.; Plaza, M.

10.1101/2021.07.29.454357 — evolutionary biology — Posted on 2021-07-30

165 Complexity-stability relationship in empirical microbial ecosystems

Yonatan, Y.; Amit, G.; Bashan, A.; Friedman, Y.

10.1101/2021.07.29.454345 — ecology — Posted on 2021-07-30

166 Patterns of morphological diversification in the Ramphastoidea reveal the dramatic divergence of toucans from a conserved morphotype

Tamma, K.; Krishnan, A.; Reddy, S.

10.1101/2021.07.29.454288 — ecology — Posted on 2021-07-30

167 Drivers of phylogenetic structure in Amazonian freshwater fish assemblages

Salgueiro Ribeiro, L.; Cassemiro, F.; Albert, J.; Frederico, R. G.; Hidalgo, M.; Hugueny, B.; Jezequel, C.; Ortega, H.; Tedesco, P.; Torrente-Vilara, G.; Zuanon, J.; Oberdorff, T.; Dias, M. S.

10.1101/2021.07.29.454320 — ecology — Posted on 2021-07-30

168 The spatiotemporal link of temporal expectations: contextual temporal expectation is independent of spatial attention

Tal-Perry, N.; Yuval-Greenberg, S.

10.1101/2021.07.30.454407 — neuroscience — Posted on 2021-07-30

169 Vergence accuracy in an autostereoscopic display

Lo Verde, L.; Norcia, A. M.

10.1101/2021.07.29.454355 — neuroscience — Posted on 2021-07-30

170 Adipogenic activity of chemicals used in plastic consumer products

Voelker, J.; Ashcroft, F.; Vedoy, A.; Zimmermann, L.; Wagner, M.

10.1101/2021.07.29.454199 — pharmacology and toxicology — Posted on 2021-07-30

171 Automatic calibration of a functional-structural wheat model using an adaptive design and a metamodelling approach

Blanc, E.; Enjalbert, J.; Barbillon, P.

10.1101/2021.07.29.454328 — bioinformatics — Posted on 2021-07-30

172 Detection and Spatiotemporal analysis of in-vitro 3D migratory Triple-Negative Breast cancer cells

Dimitriou, N. M.; Flores-Torres, S.; Kinsella, J. M.; Mitsis, G. D.

10.1101/2021.07.29.454312 — bioengineering — Posted on 2021-07-30

173 A sequence-based global map of regulatory activity for deciphering human genetics

Chen, K. M.; Wong, A. K.; Troyanskaya, O. G.; Zhou, J.

10.1101/2021.07.29.454384 — genomics — Posted on 2021-07-30

174 Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry

Kastenhuber, E. R.; Jaimes, J. A.; Johnson, J. L.; Mercadante, M.; Muecksch, F.; Weisblum, Y.; Bram, Y.; Schwartz, R. E.; Whittaker, G. R.; Cantley, L. C.

10.1101/2021.03.31.437960 — microbiology — Posted on 2021-07-30

175 Phosphorylation of PNKP mediated by CDKs promotes end-processing of Okazaki fragments during DNA replication

Tsukada, K.; Imamura, R.; Saikawa, K.; Saito, M.; Kase, N.; Miyake, T.; Ishiai, M.; Matsumoto, Y.; Shimada, M.

10.1101/2021.07.29.452278 — molecular biology — Posted on 2021-07-30

176 TNF-α levels in respiratory samples are associated with SARS-CoV-2 infection.

Pereson, M. J.; Badano, M. N.; Aloisi, N.; Chuit, R.; Braco, M. M.; Bare, P.

10.1101/2021.07.12.452071 — immunology — Posted on 2021-07-30

177 A cationic motif in Engrailed-2 homeoprotein controls its internalization via selective cell-surface glycosaminoglycans interactions

CARDON, S.; BOLBACH, G.; HERVIS, Y. P.; LOPIN-BON, C.; JACQUINET, J.-C.; ILLIEN, F.; Walrant, A.; RAVAULT, D.; HE, B.; Molina, L.; BURLINA, F.; LEQUIN, O.; JOLIOT, A.; CARLIER, L.; SAGAN, S.

10.1101/2021.07.29.454375 — biochemistry — Posted on 2021-07-30

178 NEAT-seq: Simultaneous profiling of intra-nuclear proteins, chromatin accessibility, and gene expression in single cells

Chen, A. F.; Parks, B.; Kathiria, A.; Ober-Reynolds, B.; Goronzy, J.; Greenleaf, W.

10.1101/2021.07.29.454078 — genomics — Posted on 2021-07-30

179 A cohesin traffic pattern genetically linked to gene regulation

Valton, A.-L.; Venev, S. V.; Mair, B.; Khokhar, E.; Tong, A. H.; Usaj, M.; Chan, K. S.; Pai, A.; Moffat, J.; Dekker, J.

10.1101/2021.07.29.454218 — genomics — Posted on 2021-07-30

180 Crocosphaera as a major consumer of fixed nitrogen despite its capability of nitrogen fixation

Masuda, T.; Inomura, K.; Kodama, T.; Shiozaki, T.; Kitajima, S.; Armin, G.; Matsui, T.; Suzuki, K.; Takeda, S.; Prasil, O.; Furuya, K.

10.1101/2021.07.28.454264 — microbiology — Posted on 2021-07-30

181 Viruses of Asgard archaea

Medvedeva, S.; Sun, J.; Yutin, N.; Koonin, E. V.; Nunoura, T.; Rinke, C.; Krupovic, M.

10.1101/2021.07.29.453957 — microbiology — Posted on 2021-07-30

182 The transcriptional cofactor IRF2BP2 plays a key role in T cell homeostasis and Treg cell expansion

Mognol, G. P.; Oliveira-Vieira, B.; Pinheiro-Rosa, N.; Peixoto, B. C.; Boroni, M.; Gonzalez-Avalos, E.; Secca, C.; Bandukwala, H.; Faria, A. M. C.; Rao, A.; Viola, J. P. B.

10.1101/2021.07.29.454283 — immunology — Posted on 2021-07-30

183 Control of neurotransmitter release and presynaptic plasticity by re-orientation of membrane-bound Munc13-1

Rizo, J.; Camacho, M.; Quade, B.; Trimbuch, T.; Xu, J.; Sari, L.; Rosenmund, C.

10.1101/2021.07.29.454356 — neuroscience — Posted on 2021-07-30

184 Microbiome structure of a wild Drosophila community along tropical elevational gradients and comparison to laboratory lines

Brown, J. J.; Jandova, A.; Jeffs, C. T.; Higgie, M.; Novakova, E.; Lewis, O. T.; Hrcek, J.

10.1101/2021.07.28.454263 — ecology — Posted on 2021-07-30

185 The sensory code within sense of time

Reinartz, S.; Fassihi, A.; Paz, L.; Pulecchi, F.; Gigante, M.; Diamond, M. E.

10.1101/2021.07.29.454157 — neuroscience — Posted on 2021-07-30

186 Widespread nociceptive maps in the human neonatal somatosensory cortex

Jones, L.; Verriotis, M.; Cooper, R.; Laudiano-Dray, M.; Rupawala, M.; Meek, J.; Fabrizi, L.; Fitzgerald, M.

10.1101/2021.07.29.454164 — neuroscience — Posted on 2021-07-30

187 A new protocol for multiple muscle mapping using nTMS

Jin, F.; Bruijn, S. M.; Daffertshofer, A.

10.1101/2021.07.29.454279 — neuroscience — Posted on 2021-07-30

188 A multi-omics study to investigate tacrolimus nephrotoxicity mechanisms

AOUAD, H.; FAUCHER, Q.; SAUVAGE, F.-L.; PINAULT, E.; BARROT, C.-C.; ARNION, H.; MARQUET, P.; ESSIG, M.

10.1101/2021.07.29.454229 — pharmacology and toxicology — Posted on 2021-07-30

189 Determining the stability of genome-wide factors in BMI between ages 40 to 69 years.

Gillespie, N. A.; Gentry, A. E.; Kirkpatrick, R. M.; Maes, H. H.; Reynolds, C. A.; Mathur, R.; Kendler, K. S.; Peterson, R. S.; Webb, B. T.

10.1101/2021.07.28.454172 — genetics — Posted on 2021-07-30

190 A multimodal neuroprosthetic interface to record, modulate and classify electrophysiological correlates of cognitive function

Habelt, B.; Wirth, C.; Afanasenkau, D.; Mihaylova, L.; Winter, C.; Arvaneh, M.; Minev, I.; Bernhardt, N.

10.1101/2021.07.29.454271 — neuroscience — Posted on 2021-07-30

191 EEG Alpha Power and Pupil Diameter Reflect Endogenous Auditory Attention Switching and Listening Effort

Haro, S.; Rao, H. M.; Quatieri, T. F.; Smalt, C. J.

10.1101/2021.07.29.453646 — neuroscience — Posted on 2021-07-30

192 Antibiotic treatment induces activation of microglia and impairment of cholinergic gamma oscillations in the hippocampus

Caliskan, G.; French, T.; Heimesaat, M. M.; Dunay, I. R.; Stork, O.

10.1101/2021.07.30.454300 — neuroscience — Posted on 2021-07-30

193 Age-Related Differences in Ventral Striatal and Default Mode Network Function During Reciprocated Trust

Fareri, D. S.; Hackett, K.; Tepfer, L. J.; Kelly, V. A.; Henninger, N.; Reeck, C.; Giovannetti, T.; Smith, D. V.

10.1101/2021.07.29.454071 — neuroscience — Posted on 2021-07-30

194 Functional coupling of TRPM2 and NMDARs exacerbates excitotoxicity in ischemic brain injury

Zong, P.; Feng, J.; Yue, Z.; Wu, G.; Sun, B.; He, Y.; Miller, B.; Yu, A. S.; Su, Z.; Mori, Y.; Xie, J.; Yue, L.

10.1101/2021.07.29.454247 — neuroscience — Posted on 2021-07-30

195 A comparative study between state-of-the-art MRI deidentification and AnonyMI, a new method combining re-identification risk reduction and geometrical preservation

Mikulan, E.; Russo, S.; Zauli, F. M.; d'Orio, P.; Parmigiani, S.; Favaro, J.; Knight, W.; Squarza, S.; Perri, P.; Cardinale, F.; Avanzini, P.; Pigorini, A.

10.1101/2021.07.30.454335 — neuroscience — Posted on 2021-07-30

196 Coherent mapping of position and head direction across auditory and visual cortex

Mertens, P. E. C.; Marchesi, P.; Oude Lohuis, M. N.; Krijger, Q.; Pennartz, C. M. A.; Lansink, C. S.

10.1101/2021.07.30.452931 — neuroscience — Posted on 2021-07-30

197 Distributed representations for human inference

Zhou, Z.; Singh, D.; Tandoc, M. C.; Schapiro, A. C.

10.1101/2021.07.29.454337 — neuroscience — Posted on 2021-07-30

198 An Oscillatory Mechanism for Multi-level Storage in Short-term Memory

Champion, K.; Gozel, O.; Lankow, B.; Ermentrout, B.; Goldman, M.

10.1101/2021.07.29.454329 — neuroscience — Posted on 2021-07-30

199 Cryptic genetic structure and copy-number variation in the ubiquitous forest symbiotic fungus Cenococcum geophilum

Dauphin, B.; de Freitas Pereira, M.; Kohler, A.; Grigoriev, I.; Barry, K.; Na, H.; Amirebrahimi, M.; Lipzen, A.; Martin, F.; Peter, M.; Croll, D.

10.1101/2021.07.29.454341 — genomics — Posted on 2021-07-30

200 A phylotranscriptome study using silica gel-dried leaf tissues produces an updated robust phylogeny of Ranunculaceae

He, J.; Lyu, R.; Luo, Y.; Xiao, J.; Xie, L.; Wen, J.; Li, W.; Pei, L.; Cheng, J.

10.1101/2021.07.29.454256 — evolutionary biology — Posted on 2021-07-30

201 Alpha oscillations shape sensory representation and perceptual sensitivity

Zhou, Y. J.; Iemi, L.; Schoffelen, J.-M.; de Lange, F. P.; Haegens, S.

10.1101/2021.02.02.429418 — neuroscience — Posted on 2021-07-30

202 The temperature-regulated DEAD-box RNA helicase CrhR interactome: Autoregulation and photosynthesis-related transcripts

Migur, A.; Heyl, F.; Fuss, J.; Srikumar, A.; Huettel, B.; Steglich, C.; Prakash, J. S. S.; Reinhardt, R.; Backofen, R.; Owttrim, G. W.; Hess, W. R.

10.1101/2021.03.26.437152 — plant biology — Posted on 2021-07-30

203 Effect of a low concentration in chloride, sodium and potassium on oocyte maturation, oocyte hydration, ovulation and egg quality in rainbow trout.

Segret, E.; Cardona, E.; Skiba-Cassy, S.; Cachelou, F.; Bobe, J.

10.1101/2021.06.22.449391 — physiology — Posted on 2021-07-30

204 The role of the atypical chemokine receptor CCRL2 in myelodysplastic syndrome and secondary acute myeloid leukemia

KARANTANOS, T.; Teodorescu, P.; Perkins, B.; Christodolou, I.; Esteb, C.; Varadhan, R.; Helmenstine, E.; Rajkhowa, T.; Paun, B.; Bonifant, C.; Dalton, W. B.; Gondek, L. P.; Moliterno, A. R.; Levis, M. J.; Ghiaur, G.; Jones, R. J.

10.1101/2021.07.29.454394 — cancer biology — Posted on 2021-07-30

205 Investigating molecular crowding during cell division in budding yeast with FRET

Lecinski, S.; Shepherd, J.; Frame, L.; Hayton, I.; MacDonald, C.; Leake, M. C.

10.1101/2021.07.29.454334 — biophysics — Posted on 2021-07-30

206 SF3B1 promotes tumor malignancy through splicing-independent co-activation of HIF1α

Simmler, P.; Cortijo, C.; Koch, L. M.; Galliker, P.; Schaefer, M.; Angori, S.; Bolck, H. A.; Mueller, C.; Vukolic, A.; Mirtschink, P.; Christinat, Y.; Davidson, N. R.; Lehmann, K.-V.; Pellegrini, G.; Pauli, C.; Lenggenhager, D.; Guccini, I.; Ringel, T.; Hirt, C.; Raetsch, G.; Moch, H.; Stoffel, M.; Schwank, G.

10.1101/2020.11.10.376780 — cell biology — Posted on 2021-07-30

207 Detection and quantification of the vacuolar H ATPase using the Legionella effector protein SidK

Maxson, M.; Abbas, Y. M.; Wu, J. Z.; Grinstein, S.; Rubinstein, J. L.

10.1101/2021.07.29.454369 — cell biology — Posted on 2021-07-30

208 In vivo KRAS G12D/V Degradation Mediated by CANDDY Using a Modified Proteasome Inhibitor

Imanishi, S.; Huang, L.; Itakura, S.; Ishizaka, M.; Iwasaki, Y.; Yamaguchi, T.; Miyamoto-Sato, E.

10.1101/2021.04.23.441075 — molecular biology — Posted on 2021-07-30

209 RNA uridyl transferases TUT4/7 differentially regulate miRNA variants depending on the cancer cell-type

Medhi, R.; Price, J.; Furlan, G.; Gorges, B.; Sapetschnig, A.; Miska, E. A.

10.1101/2021.07.12.451846 — molecular biology — Posted on 2021-07-30

210 Topological Sholl Descriptors For Neuronal Clustering and Classification

Khalil, R.; Kallel, S.; Dlotko, P.; Farhat, A.

10.1101/2021.01.15.426800 — neuroscience — Posted on 2021-07-30

211 The optimal spatial arrangement of ON and OFF receptive fields

Jun, N. Y.; Field, G. D.; Pearson, J. M.

10.1101/2021.03.10.434612 — neuroscience — Posted on 2021-07-30

212 Mapping the sequence specificity of heterotypic amyloid interactions enables the identification of aggregation modifiers

Louros, N. N.; Ramakers, M.; Michiels, E.; Konstantoulea, K.; Morelli, C.; Garcia, T.; D'Haeyer, S.; Goossens, V.; Audenaert, D.; Rousseau, F.; Schymkowitz, J.

10.1101/2021.06.04.447096 — biophysics — Posted on 2021-07-30

213 Towards a comprehensive delineation of white matter tract-related deformation

Zhou, Z.; Li, X.; Liu, Y.; Fahlstedt, M.; Georgiadis, M.; Zhan, X.; Raymond, S. J.; Grant, G.; Kleiven, S.; Camarillo, D.; Zeineh, M. M.

10.1101/2021.04.13.439136 — bioengineering — Posted on 2021-07-30

214 Phenotypic architecture of sociality and its associated genetic polymorphisms in zebrafish

Oliveira, R. F.; Goncalves, C.; Kareklas, K.; Teles, M. C.; Varela, S. A. M.; Costa, J.; Leite, R. B.; Paixao, T.

10.1101/2021.07.29.454277 — animal behavior and cognition — Posted on 2021-07-30

215 A burst of regulatory and protein innovation at the origin of placental mammals drove the emergence of placenta and underpins divergent early pregnancy strategies in modern mammals.

Taylor, A. S.; Tinning, H.; Ovchinnikov, V.; Smith, W.; Pullinger, A. L.; Sutton, R. A.; Constantinides, B.; Wang, D.; Forde, N.; O'Connell, M. J.

10.1101/2021.07.22.453388 — evolutionary biology — Posted on 2021-07-29

216 Circadian key component CLOCK/BMAL1 interferes with segmentation clock in mouse embryonic organoids

Umemura, Y.; Koike, N.; Tsuchiya, Y.; Watanabe, H.; Kondoh, G.; Kageyama, R.; Yagita, K.

10.1101/2020.10.30.362830 — developmental biology — Posted on 2021-07-30

217 Identification and characterisation of splicing regulators in Toxoplasma gondii

Lee, V. V.; Seizova, S.; McMillan, P.; McHugh, E.; Tonkin, C.; Ralph, S.

10.1101/2021.06.27.450092 — cell biology — Posted on 2021-07-29

218 Recent SIV-Macaque Trials: A Reassessment of Immune Priming and Varying Infectability in Repeated Low-dose Challenge Studies

Spouge, J. L.

10.1101/2021.07.28.454270 — microbiology — Posted on 2021-07-29

219 Model-based inference of neutralizing antibody avidities against influenza virus

Linnik, J.; Syedbasha, M.; Hollenstein, Y.; Halter, J.; Egli, A.; Stelling, J.

10.1101/2020.10.05.326215 — immunology — Posted on 2021-07-29

220 Sex differences and estradiol effects in MAPK and Akt cell signaling across subregions of the hippocampus

Sheppard, P. A.; Puri, T.; Galea, L. A.

10.1101/2021.05.30.446341 — neuroscience — Posted on 2021-07-29

221 Fear Conditioning Potentiates the Hippocampal CA1 Commissural Pathway In vivo and Increases Awake Phase Sleep

Subramaniyan, M.; Manivannan, S.; Chelur, V.; Tsetsenis, T.; Jiang, E.; Dani, J. A.

10.1101/2020.05.13.093237 — neuroscience — Posted on 2021-07-29

222 PiRATeMC: A highly flexible, scalable, and affordable system for obtaining high quality video recordings for behavioral neuroscience.

Centanni, S. W.; Smith, A. C.

10.1101/2021.07.23.453577 — neuroscience — Posted on 2021-07-30

223 Lignin-based resistance to Cuscuta campestris parasitism in Heinz resistant tomato cultivars

Jhu, M.-Y.; Farhi, M.; Wang, L.; Philbrook, R. N.; Belcher, M. S.; Nakayama, H.; Zumstein, K. S.; Rowland, S. D.; Ron, M.; Shih, P. M.; Sinha, N. R.

10.1101/706861 — plant biology — Posted on 2021-07-29

224 Critical re-evaluation of the slope factor of the operational model of agonism

Jakubik, J.

10.1101/2021.04.07.438803 — pharmacology and toxicology — Posted on 2021-07-29

225 A Computational Model of Phosphene Appearance for Epiretinal Prostheses

Granley, J.; Beyeler, M.

10.1101/2021.06.07.447426 — bioengineering — Posted on 2021-07-29

226 Predicting continuous ground reaction forces from accelerometers during uphill and downhill running: A recurrent neural network solution

Alcantara, R. S.; Edwards, W. B.; Millet, G. Y.; Grabowski, A. M.

10.1101/2021.03.17.435901 — bioengineering — Posted on 2021-07-29

227 Effects of domestication on neophobia: A comparison between the domesticated Bengalese finch (Lonchura striata var. domestica) and its wild ancestor, the white-rumped munia (Lonchura striata)

Suzuki, K.; Ikebuchi, M.; Kagawa, H.; Koike, T.; Okanoya, K.

10.1101/2021.03.23.436696 — animal behavior and cognition — Posted on 2021-07-29

228 Construction of transcript regulation mechanism prediction models based on binding motif environment of transcription factor AoXlnR in Aspergillus oryzae

Oka, H.; KOJIMA, T.; Kato, R.; Ihara, K.; Nakano, H.

10.1101/2021.07.28.454268 — genomics — Posted on 2021-07-29

229 Priors, population sizes, and power in genome-wide hypothesis tests

Cai, J. S.; Zhan, J.; Arking, D. E.; Bader, J. S.

10.1101/737676 — genetics — Posted on 2021-07-29

230 Ecdysone coordinates plastic growth with robust pattern in the developing wing

Nogueira Alves, A.; Oliveira, M. M.; Koyama, T.; Shingleton, A.; Mirth, C.

10.1101/2020.12.16.423141 — developmental biology — Posted on 2021-07-29

231 Rapid redistribution and extensive binding of NANOG and GATA6 at shared regulatory elements underlie specification of divergent cell fates

Thompson, J. J.; Lee, D. J.; Mitra, A.; Frail, S.; Dale, R.; Rocha, P. P.

10.1101/2021.07.28.454132 — developmental biology — Posted on 2021-07-29

232 Metal-Organic Framework Encapsulated Whole-Cell Vaccines Enhance Humoral Immunity against Bacterial Infection

Luzuriaga, M. A.; Herbert, F. C.; Brohlin, O.; Gadhvi, J.; Howlett, T.; Shahrivarkevishahi, A.; Wijesundara, Y. H.; Venkitapathi, S.; Veera, K.; Ehrman, R.; Benjamin, C. E.; Popal, S.; Burton, M. D.; Ingersoll, M. A.; De Nisco, N. J.; Gassensmith, J. J.

10.1101/2020.06.14.148452 — immunology — Posted on 2021-07-29

233 Reliability of Mouse Behavioural Tests of Anxiety: a Systematic Review and Meta-Analysis on the Effects of Anxiolytics.

Rosso, M.; Wirz, R.; Loretan, A. V.; Sutter, N. A.; Pereira da Cunha, C. T.; Jaric, I.; Würbel, H.; Voelkl, B.

10.1101/2021.07.28.454267 — neuroscience — Posted on 2021-07-29

234 Double nerve transfer to a single target muscle: experimental model in the upper extremity

Luft, M.; Klepetko, J.; Muceli, S.; Ibanez, J.; Tereshenko, V.; Festin, C.; Laengle, G.; Politikou, O.; Maierhofer, U.; Farina, D.; Aszmann, O. C.; Bergmeister, K. D.

10.1101/2021.07.09.451759 — neuroscience — Posted on 2021-07-29

235 Natural Image Statistics for Mouse Vision

Abballe, L.; Asari, H.

10.1101/2021.04.08.438953 — neuroscience — Posted on 2021-07-29

236 WAPO-A1 is the causal gene of the 7AL QTL for spikelet number per spike in wheat

Kuzay, S.; Lin, H.; Li, C.; Chen, S.; Woods, D.; Zhang, J.; Dubcovsky, J.

10.1101/2021.07.29.454276 — plant biology — Posted on 2021-07-29

237 Small extracellular vesicles from young mice prevent frailty and improve healthspan in old mice.

Sanz-Ros, J.; Mas-Bargues, C.; Monleon, D.; Dromant, M.; Derevyanko, A.; Guio-Carrion, A.; Roman-Dominguez, A.; Romero-Garcia, N.; Ingles, M.; Blasco, M. A.; Vina, J.; Borras, C.

10.1101/2021.07.29.454302 — physiology — Posted on 2021-07-29

238 ZBTB18 inhibits SREBP-dependent fatty acid synthesis by counteracting CTBPs and KDM1A/LSD1 activity in glioblastoma

Ferrarese, R.; Izzo, A.; Andrieux, G.; Lagies, S.; Bartmuss, J. P.; Masilamani, A. P.; Wasilenko, A.; Osti, D.; Faletti, S.; Schulzki, R.; Yuan, S.; Kling, E.; Ribecco, V.; Heiland, H. D.; Tholen, S. G.; Prinz, M.; Pelicci, G.; Kammerer, B.; Boerries, M.; Carro, M. S.

10.1101/2020.04.17.046268 — cancer biology — Posted on 2021-07-29

239 SUITOR: selecting the number of mutational signatures through cross-validation

Lee, D.; Wang, D.; Yang, X. R.; Shi, J.; Landi, M. T.; Zhu, B.

10.1101/2021.07.28.454269 — bioinformatics — Posted on 2021-07-29

240 A Non-Canonical Raf Function Is Required for Dorsal-Ventral Patterning During Drosophila Embryogenesis

Tolwinski, N. S.; Lusk, J. B.; Chua, E. H. Z.; Kaur, P.; Sung, I. C. H.; Lim, W. K.; Lam, V. Y. M.; Harmston, N.

10.1101/2021.07.29.454294 — developmental biology — Posted on 2021-07-29

241 Endogenous protein tagging in medaka using a simplified CRISPR/Cas9 knock-in approach

Seleit, A.; Aulehla, A.; Paix, A.

10.1101/2021.07.29.454295 — developmental biology — Posted on 2021-07-29

242 Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline

Graniel, J. V.; Bisht, K.; Friedman, A.; White, J.; Perkey, E.; Vanderbeck, A.; Moroz, A.; Carrington, L. J.; Brandstadter, J. D.; Allen, F.; Shami, A. N.; Thomas, P.; Crayton, A.; Manzor, M.; Mychalowych, A.; Chase, J.; Hammoud, S. S.; Keegan, C. E.; Maillard, I.; Nandakumar, J.

10.1101/2021.07.29.454392 — cell biology — Posted on 2021-07-29

243 Calcium-binding protein S100A6 interaction with VEGF receptors integrates signaling and trafficking pathways

Ponnambalam, S.; Bao, L.; Fearnley, G. W.; Lin, C.-C.; Odell, A. F.; Redondo, A. C.; Kinsella, G. K.; Findlay, J. B. C.; Ladbury, J. E.; Harrison, M.

10.1101/2021.07.29.454311 — cell biology — Posted on 2021-07-29

244 METTL18-mediated histidine methylation on RPL3 modulates translation elongation for proteostasis maintenance

Matsuura-Suzuki, E.; Shimazu, T.; Takahashi, M.; Kotoshiba, K.; Suzuki, T.; Kashiwagi, K.; Sohtome, Y.; Akakabe, M.; Sodeoka, M.; Dohmae, N.; Ito, T.; Shinkai, Y.; Iwasaki, S.

10.1101/2021.07.29.454307 — molecular biology — Posted on 2021-07-29

245 Extending the gap and loading RecA: the presynaptic phase plays a pivotal role in modulating lesion tolerance pathways

Laureti, L.; Lee, L.; Philippin, G.; Kahi, M.; Pages, V.

10.1101/2021.07.29.454318 — molecular biology — Posted on 2021-07-29

246 Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3(ATR) kinase is essential in the absence of Rqh1(BLM) helicase

Giaccherini, C.; Scaglione, S.; Coulon, S.; Dehé, P.-M.; GAILLARD, P. H. L.

10.1101/2021.07.29.454171 — molecular biology — Posted on 2021-07-29

247 Deficiency in cytosine DNA methylation leads to high chaperonin expression and tolerance to aminoglycosides in Vibrio cholerae

Carvalho, A.; Mazel, D.; Baharoglu, Z.

10.1101/2021.07.29.454301 — microbiology — Posted on 2021-07-29

248 TOR kinase controls shoot development by translational regulation of cytokinin catabolic enzymes

Janocha, D.; Pfeiffer, A.; Dong, Y.; Novak, O.; Strnad, M.; Ryabova, L.; Lohmann, J. U.

10.1101/2021.07.29.454319 — plant biology — Posted on 2021-07-29

249 Nephrotoxicity of Calcineurin Inhibitors in kidney epithelial cells is independent of Calcineurin and NFAT signaling.

Karolin, A.; Escher, G.; Rudloff, S.; Sidler, D.

10.1101/2021.07.29.454219 — pharmacology and toxicology — Posted on 2021-07-29

250 Semaphorin 3C exacerbates liver fibrosis

De Angelis Rigotti, F.; Wiedmann, L.; Hubert, M. O.; Vacca, M.; Hasan, S. S.; Moll, I.; Carvajal, S.; Jimenez, W.; Starostecka, M.; Billeter, A. T.; Müller-Stich, B.; Wolff, G.; Ekim-Üstünel, B.; Herzig, S.; Mogler, C.; Fischer, A.; Rodriguez-Vita, J.

10.1101/2021.07.29.454292 — pathology — Posted on 2021-07-29

251 Cellular organization in lab-evolved and extant multicellular species obeys a maximum entropy law

Day, T. C.; Höhn, S. S.; Zamani-Dahaj, S. A.; Yanni, D.; Burnetti, A.; Pentz, J.; Honerkamp-Smith, A. R.; Wioland, H.; Sleath, H. R.; Ratcliff, W. C.; Goldstein, R. E.; Yunker, P. J.

10.1101/2021.07.29.454238 — biophysics — Posted on 2021-07-29

252 Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins

Healy, M. D.; Sacharz, J.; McNally, K. E.; McConville, C.; Hall, R. J.; Chilton, M.; Cullen, P. J.; Mobli, M.; Ghai, R.; Stroud, D. A.; Collins, B.

10.1101/2021.07.29.454387 — biochemistry — Posted on 2021-07-29

253 Chromosome-level genome assembly of Japanese chestnut (Castanea crenata Sieb. et Zucc.) reveals conserved chromosomal segments in woody rosids

Shirasawa, K.; Nishio, S.; Terakami, S.; Botta, R.; Torello Marinoni, D.; Isobe, S.

10.1101/2021.07.29.454274 — genomics — Posted on 2021-07-29

254 Cryptic genetic structure and copy-number variation in the ubiquitous forest symbiotic fungus Cenococcum geophilum

Dauphin, B.; de Freitas Pereira, M.; Kohler, A.; Grigoriev, I.; Barry, K.; Na, H.; Amirebrahimi, M.; Lipzen, A.; Martin, F.; Peter, M.; Croll, D.

10.1101/2021.07.29.454341 — genomics — Posted on 2021-07-29

255 Targeted resurrection of chromosomal arm 1RS in two elite wheat lines with 1BL/1RS translocation for improved end-use quality

Kaur, R.; Dhillon, G. S.; Kaur, A.; Kaur, S.; Kaur, P.; Kaur, D.; Kumar, A.; Singh, R.; Mavi, G. S.; Grewal, S. K.; Chhuneja, P.; Kaur, S.

10.1101/2021.07.29.454297 — genetics — Posted on 2021-07-29

256 Natural interploidy hybridization among the key taxa involved in the origin of horticultural chrysanthemums

Qi, S.; Twyford, A. D.; Ding, J.; Borrell, J. S.; Ma, Y.; Wang, N.

10.1101/2021.07.29.454281 — evolutionary biology — Posted on 2021-07-29

257 A phylotranscriptome study using silica gel-dried leaf tissues produces an updated robust phylogeny of Ranunculaceae

He, J.; Lyu, R.; Luo, Y.; Xiao, J.; Xie, L.; Wen, J.; Li, W.; Pei, L.; Cheng, J.

10.1101/2021.07.29.454256 — evolutionary biology — Posted on 2021-07-29

258 Systemic antibody-oligonucleotide delivery to the central nervous system ameliorates mouse models of spinal muscular atrophy

Hammond, S. M.; Abendroth, F.; Goli, L.; Burrell, M.; Thom, G.; Gurrell, I.; Stoodley, J.; Ahlskog, N.; Gait, M. J.; Wood, M.; Webster, C.

10.1101/2021.07.29.454272 — molecular biology — Posted on 2021-07-29

259 The HMCES DNA-protein cross-link functions as a constitutive DNA repair intermediate

Semlow, D. R.; MacKrell, V. A.; Walter, J.

10.1101/2021.07.29.454365 — molecular biology — Posted on 2021-07-29

260 m6A-mediated Cell-cell Communication Controls Planarian Regeneration

Cui, G.; Zhou, J.-Y.; Ge, X.-Y.; Sun, B.-F.; Song, G.-G.; Wang, X.; Wang, X.-Z.; Zhang, R.; Wang, H.; Jing, Q.; Zhao, Y.; Koziol, M.; Zeng, A.; Zhang, W.; Han, D.; Yang, Y.; Yang, Y.-G.

10.1101/2021.07.29.454253 — molecular biology — Posted on 2021-07-29

261 HEPG2 EXPRESSION OF MIR-202 & TRIB-1 UNDER METABOLIC AND INFLAMMATORY STRESS.

Phillip, I. O.; Phillip, J. O.

10.1101/2021.07.29.454303 — molecular biology — Posted on 2021-07-29

262 Unique viruses that infect Archaea related to eukaryotes

Rambo, I. M.; De Anda, V.; Langwig, M. V.; Baker, B. J.

10.1101/2021.07.29.454249 — microbiology — Posted on 2021-07-29

263 Transcription-coupled DNA repair underlies variation in persister awakening and the emergence of resistance

Wilmaerts, D.; Focant, C.; Matthay, P.; Michiels, J.

10.1101/2021.07.29.454265 — microbiology — Posted on 2021-07-29

264 ASSEMBLY AND DYNAMICS OF MICROBIAL COMMUNITIES IN GRANULAR, FIXED-BIOFILM AND PLANKTONIC METHANOGENIC MICROBIOMES VALORIZING LONG CHAIN FATTY ACID (LCFA)-RICH WASTEWATER

Singh, S.; Rinta-Kanto, J. M.; Lens, P. N. L.; Kokkoa, M.; Rintala, J.; O'Flaherty, V.; Ijaz, U. Z.; Collins, G.

10.1101/2021.07.29.454224 — microbiology — Posted on 2021-07-29

265 Visual exposure enhances stimulus encoding and persistence in primary cortex

Lazar, A.; Lewis, C.; Fries, P.; Singer, W.; Nikolic, D.

10.1101/502328 — neuroscience — Posted on 2021-07-29

266 HGFAC is a ChREBP Regulated Hepatokine that Enhances Glucose and Lipid Homeostasis

10.1101/2021.07.29.454308 — physiology — Posted on 2021-07-29

267 Deep learning identifies and quantifies recombination hotspot determinants

Li, Y.; Chen, S.; Rapakoulia, T.; Kuwahara, H.; Yip, K.; Gao, X.

10.1101/2021.07.29.454133 — bioinformatics — Posted on 2021-07-29

268 Increasing cell size remodels the proteome and promotes senescence

Lanz, M. C.; Zatulovskiy, E.; Swaffer, M. P.; Zhang, L.; Zhang, S.; You, D. S.; Marinov, G. K.; McAlpine, P.; Elias, J. E.; Skotheim, J. M.

10.1101/2021.07.29.454227 — cell biology — Posted on 2021-07-29

269 Vimentin Intermediate Filaments and Filamentous Actin Form Unexpected Interpenetrating Networks That Redefine the Cell Cortex

Wu, H.; Shen, Y.; Sivagurunathan, S.; Weber, M. S.; Adam, S. A.; Shin, J. H.; Fredberg, J. J.; Medalia, O.; Goldman, R.; Weitz, D. A.

10.1101/2021.07.29.454155 — cell biology — Posted on 2021-07-29

270 Astragalus Saponins, Astragaloside VII and Newly Synthesized Derivatives, Induce Dendritic Cell Maturation and T Cell Activation Through IL-1β Production

Yakubogullari, N.; Cagir, A.; Bedir, E.; Sag, D.

10.1101/2021.07.29.454313 — immunology — Posted on 2021-07-29

271 Human brain anatomy reflects separable genetic and environmental components of socioeconomic status

Kweon, H.; Aydogan, G.; Dagher, A.; Bzdok, D.; Ruff, C. C.; Nave, G.; Farah, M. J.; Koellinger, P. D.

10.1101/2021.07.28.454131 — neuroscience — Posted on 2021-07-29

272 Ageing and the ipsilateral M1 BOLD response: a connectivity study

Tak, Y. W.; Knights, E.; Henson, R.; Zeidman, P.

10.1101/2021.07.29.454012 — neuroscience — Posted on 2021-07-29

273 Multiplexed Imaging Mass Cytometry of Chemokine Milieus in Metastatic Melanoma Characterizes Features of Response to Immunotherapy

Hoch, T.; Schulz, D.; Eling, N.; Martlnez Gomez, J.; Levesque, M. P.; Bodenmiller, B.

10.1101/2021.07.29.454093 — cancer biology — Posted on 2021-07-29

274 Collective Mechanical Responses of Cadherin-Based Adhesive Junctions as Predicted by Simulations

Neel, B. L.; Nisler, C. R.; Walujkar, S.; Araya-Secchi, R.; Sotomayor, M.

10.1101/2021.07.29.454068 — biophysics — Posted on 2021-07-29

275 Impaired activation of Transposable Elements in SARS-CoV-2 infection

Sorek, M.; Meshorer, E.; Schlesinger, S.

10.1101/2021.02.25.432821 — bioinformatics — Posted on 2021-07-29

276 The META tool optimizes metagenomic analyses across sequencing platforms and classifiers.

Player, R. A.; Aguinaldo, A. M.; Merritt, B. B.; Maszkiewicz, L. N.; Adeyemo, O. E.; Forsyth, E. R.; Verratti, K. J.; Chee, B. W.; Grady, S. L.; Bradburne, C. E.

10.1101/2021.07.29.454031 — bioinformatics — Posted on 2021-07-29

277 Placental gene expression-based cell type deconvolution: Cell proportions drive preeclampsia gene expression differences

Campbell, K. A.; Colacino, J. A.; Puttabyatappa, M.; Dou, J.; Elkin, E. R.; Hammoud, S. S.; Domino, S. E.; Dolinoy, D. C.; Goodrich, J. M.; Loch-Caruso, R.; Padmanabhan, V.; Bakulski, K. M.

10.1101/2021.07.29.454041 — developmental biology — Posted on 2021-07-29

278 ADAD2 regulates heterochromatin in meiotic and post-meiotic male germ cells via translation of MDC1

Chukrallah, L. G.; Badrinath, A.; Vittor, G. G.; Snyder, E. M.

10.1101/2021.07.29.454317 — cell biology — Posted on 2021-07-29

279 Genome-wide characterization of Salmonella Typhimurium genes required for the fitness under iron restriction

Karash, S.; Jiang, T.; Kwon, Y. M.

10.1101/2021.07.28.454258 — microbiology — Posted on 2021-07-29

280 A binary effector module secreted by a type VI secretion system

Dar, Y.; Jana, B.; Bosis, E.; Salomon, D.

10.1101/2021.07.29.453783 — microbiology — Posted on 2021-07-29

281 High-amplitude network co-fluctuations linked to variation in hormone concentrations over menstrual cycle

Greenwell, S.; Faskowitz, J.; Pritschet, L.; Santander, T.; Jacobs, E. G.; Betzel, R.

10.1101/2021.07.29.453892 — neuroscience — Posted on 2021-07-29

282 Outer Hair Cell Power Output and the Cellular Origins of Distortion Products

Rabbitt, R. D.

10.1101/2021.07.29.454372 — physiology — Posted on 2021-07-29

283 Optimizing large organ scale micro computed tomography imaging in pig and human hearts using a novel air-drying technique

Pallares-Lupon, N.; Ramlugun, G. S.; Ozenne, V.; Duchateau, J.; Delgove, A.; Bayer, J. D.; Moreno, A.; Constantin, M.; Gerneke, D.; Sands, G. B.; Trew, M. L.; Hocini, M.; Haissaguerre, M.; Vigmond, E. J.; Quesson, B.; Bernus, O.; Walton, R. D.

10.1101/2021.07.29.454121 — physiology — Posted on 2021-07-29

284 Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing

Frey, N.; Tortola, L.; Egli, D.; Janjuha, S.; Marquart, K. F.; Rothgangl, T.; Ampenberger, F.; Kopf, M.; Schwank, G.

10.1101/2021.07.29.453937 — cancer biology — Posted on 2021-07-29

285 Elastic versus Brittle Mechanical Responses Predicted for Dimeric Cadherin Complexes

Neel, B. L.; Nisler, C. R.; Walujkar, S.; Araya-Secchi, R.; Sotomayor, M.

10.1101/2021.07.29.454067 — biophysics — Posted on 2021-07-29

286 Dual Roles for Nuclear RNAi Argonautes in C. elegans Dosage Compensation

Davis, M. B.; Chawla, B.; Jash, E.; Tushman, L. E.; Haines, R. A.; Csankovszki, G.

10.1101/2021.07.29.454039 — genetics — Posted on 2021-07-29

287 Population genomic consequences of novel life history and mating system adaptation to a geothermal soil mosaic in yellow monkeyflowers (Mimulus guttatus)

Kolis, K. M.; Berg, C. S.; Nelson, T. C.; Fishman, L.

10.1101/2021.07.29.453448 — evolutionary biology — Posted on 2021-07-29

288 Stabilizing selection shapes variation in phenotypic plasticity

Becker, D.; Barnard-Kubow, K.; Porter, R.; Edwards, A.; Voss, E.; Beckerman, A. P.; Bergland, A. O.

10.1101/2021.07.29.454146 — evolutionary biology — Posted on 2021-07-29

289 European-wide forest monitoring substantiate the neccessity for a joint conservation strategy to rescue European ash species (Fraxinus spp.)

George, J.-P.; Sanders, T. G.; Timmermann, V.; Potocic, N.; Lang, M.

10.1101/2021.07.28.454255 — ecology — Posted on 2021-07-29

290 Quantifying epigenetic modulation of nucleosome breathing by high-throughput AFM imaging

Konrad, S. F.; Vanderlinden, W.; Lipfert, J.

10.1101/2021.07.29.454136 — molecular biology — Posted on 2021-07-29

291 Competitive advantage of oral streptococci for colonization of the middle ear mucosa

Jacob, K. M.; Reguera, G.

10.1101/2021.07.28.454259 — microbiology — Posted on 2021-07-29

292 Clostridioides difficile SpoVAD and SpoVAE interact and are required for DPA packaging into spores

Baloh, M.; Sorg, J. A.

10.1101/2021.07.28.454260 — microbiology — Posted on 2021-07-29

293 mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status

Neidleman, J.; Luo, X.; McGregor, M.; Xie, G.; Murray, V.; Greene, W. C.; Lee, S. A.; Roan, N. R.

10.1101/2021.05.12.443888 — immunology — Posted on 2021-07-29

294 Heme-stress activated NRF2 signaling skews fate trajectories of bone marrow cells from dendritic cells towards red pulp-like macrophages

Vallelian, F.; Buzzi, R. M.; Pfefferle, M.; Yalamanoglu, A.; Wassmer, A.; Gentinetta, T.; Hansen, K.; Humar, R.; Schulthess, N.; Schaer, D. J.

10.1101/2021.07.29.454342 — immunology — Posted on 2021-07-29

295 Mutant huntingtin crosses the neuromuscular junction and causes transmission-selective pathological alterations in huntingtin expressing myotubes

Dinamarca Ceballos, M.; Colombo, L.; Brykczynska, U.; Grimm, A.; Tousiaki, E. N.; Fruh, I.; Hossain, I.; Gabriel, D.; Eckert, A.; Mueller, M.; Pecho-Vrieseling, E.

10.1101/2021.07.28.454044 — neuroscience — Posted on 2021-07-29

296 Genome-scale metabolic modelling of lifestyle changes in Rhizobium leguminosarum

Schulte, C. C. M.; Ramachandran, V.; Papachristodoulou, A.; Poole, P.

10.1101/2021.07.28.454262 — systems biology — Posted on 2021-07-29

297 Photoacoustic-MR Images Registration Based on Co-Sparse Analysis Model to Compensate for Brain Shift

Farnia, P.; Makkiabadi, B.; Alimohammadi, M.; Najafzadeh, E.; Basij, M.; Yan, Y.; Ahmadian, A.; Mehrmohammadi, M.

10.1101/2021.07.28.453095 — bioengineering — Posted on 2021-07-29

298 High-resolution protein fragment interactions using AVA-Seq on a human reference set

Ramadan, S.; Aleksic, J.; Al-Thani, N. M.; Mohamoud, Y. A.; Hill, D. E.; Malek, J. A.

10.1101/2021.07.28.454266 — genomics — Posted on 2021-07-29

299 SARS-CoV-2 exposure in wild white-tailed deer (Odocoileus virginianus)

Chandler, J. C.; Bevins, S. N.; Ellis, J. W.; Linder, T. J.; Tell, R. M.; Jenkins-Moore, M.; Root, J. J.; Lenoch, J. B.; Robbe-Austerman, S.; DeLiberto, T. J.; Gidlewski, T.; Torchetti, M. K.; Shriner, S. A.

10.1101/2021.07.29.454326 — microbiology — Posted on 2021-07-29

300 Antibody Evolution after SARS-CoV-2 mRNA Vaccination

Cho, A.; Muecksch, F.; Schaefer-Babajew, D.; Wang, Z.; Finkin, S.; Gaebler, C.; Ramos, V.; Cipolla, M.; Agudelo, M.; Bednarski, E.; DaSilva, J.; Shimeliovich, I.; Dizon, J.; Daga, M.; Millard, K.; Turroja, M.; Schmidt, F.; Zhang, F.; Ben Tanfous, T.; Jankovic, M.; Oliveira, T.; Gazumyan, A.; Caskey, M.; Bieniasz, P. D.; Hatziioannou, T.; Nussenzweig, M. C.

10.1101/2021.07.29.454333 — immunology — Posted on 2021-07-29

301 Structural basis for recognition of two HLA-A2-restricted SARS-CoV-2 spike epitopes by public and private T cell receptors

Wu, D.; Kolesnikov, A.; Yin, R.; Guest, J. D.; Gowthaman, R.; Shmelev, A.; Serdyuk, Y.; Efimov, G. A.; Pierce, B. G.; Mariuzza, R. A.

10.1101/2021.07.28.454232 — immunology — Posted on 2021-07-29

302 Inferring cell-cell interactions from pseudotime ordering of scRNA-Seq data

Li, D.; Velazquez, J. J.; Ding, J.; Hislop, J.; Ebrahimkhani, M. R.; Bar-Joseph, Z.

10.1101/2021.07.28.454054 — bioinformatics — Posted on 2021-07-29

303 The economical lifestyle of CPR bacteria in groundwater allows little preference for environmental drivers

Chaudhari, N. M.; Overholt, W. A.; Figueroa-Gonzalez, P. A.; Taubert, M.; Bornemann, T. L. V.; Probst, A. J.; Hölzer, M.; Marz, M.; Küsel, K.

10.1101/2021.07.28.454184 — microbiology — Posted on 2021-07-29

304 Machine learning uncovers a data-driven transcriptional regulatory network for the Crenarchaeal thermoacidophile Sulfolobus acidocaldarius

Chauhan, S. M.; Poudel, S.; Rychel, K.; Lamoureux, C.; Yoo, R.; Al Bulushi, T.; Yuan, Y.; Palsson, B.; Sastry, A. V.

10.1101/2021.07.28.454237 — systems biology — Posted on 2021-07-29

305 Normalized coefficient of variation (nCV): a method to evaluate circadian clock robustness in population scale data

Wu, G.; Francey, L. J.; Ruben, M. D.; Hogenesch, J. B.

10.1101/2021.07.28.454045 — systems biology — Posted on 2021-07-29

306 Identification of TAZ as the essential molecular switch in orchestrating SCLC phenotypic transition and metastasis

Ji, h.; Jin, Y.; Zhao, Q.; Zhu, W.; Feng, Y.; Xiao, T.; Zhang, P.; Jiang, L.; Hou, Y.; Guo, C.; Huang, H.; Chen, Y.; Tong, X.; Cao, J.; Zhu, X.; Qin, J.; Gao, D.; Liu, X.-y.; Zhang, H.; Chen, L.; Thomas, R. K.; Wong, K.-K.; Wang, Y.; Hu, L.

10.1101/2021.07.28.454244 — cancer biology — Posted on 2021-07-29

307 A Topological Data Analytic Approach for Discovering Biophysical Signatures in Protein Dynamics

Tang, W. S.; da Silva, G. M.; Kirveslahti, H.; Skeens, E.; Feng, B.; Sudijono, T.; Yang, K. K.; Mukherjee, S.; Rubenstein, B.; Crawford, L.

10.1101/2021.07.28.454240 — biophysics — Posted on 2021-07-29

308 Automated Reconstruction of Whole-Embryo Cell Lineages by Learning from Sparse Annotations

Malin-Mayor, C.; Hirsch, P.; Guignard, L.; McDole, K.; Wan, Y.; Lemon, W. C.; Keller, P. J.; Preibisch, S.; Funke, J.

10.1101/2021.07.28.454016 — bioinformatics — Posted on 2021-07-29

309 EffectorP 3.0: prediction of apoplastic and cytoplasmic effectors in fungi and oomycetes

Sperschneider, J.; Dodds, P.

10.1101/2021.07.28.454080 — bioinformatics — Posted on 2021-07-29

310 InDeep : 3D fully convolutional neural networks to assist in silico drug design on protein-protein interactions

Mallet, V.; Ruano, L. C.; Moine-Franel, A.; Nilges, M.; Druart, K.; Bouvier, G.; Sperandio, O.

10.1101/2021.07.28.453974 — bioinformatics — Posted on 2021-07-29

311 Using Bayesian Inference to Estimate Plausible Muscle Forces in Musculoskeletal Models

Johnson, R. T.; Lakeland, D.; Finley, J. M.

10.1101/2021.07.28.454251 — bioengineering — Posted on 2021-07-29

312 Hormonal contraceptives alter amphetamine place preference and responsivity in the intact female rat.

Hilz, E. N.; Olvera, M.; Jun, D. S.; Chadha, M.; Gillette, R.; Monfils, M. H.; Gore, A. C.; Lee, H. J.

10.1101/2021.07.28.454029 — animal behavior and cognition — Posted on 2021-07-29

313 Outcome-selective reinstatement is partially context-dependent, and associated with c-Fos activation in the posterior dorsomedial striatum

Abiero, A.; Ali, Z.; Vissel, B.; Bradfield, L.

10.1101/2021.07.28.454246 — animal behavior and cognition — Posted on 2021-07-29

314 The swine spatiotemporal H3K27ac spectrum provides novel resources for exploring gene regulation related to complex traits and fundamental biological process

Huang, L.; Zhu, Y.; Zhou, Z.; Huang, T.; Zhang, Z.; Li, W.; Ling, Z.; Jiang, T.; Yang, J.; Yang, S.; Xiao, Y.; Charlier, C.; Georges, M.; Yang, B.

10.1101/2021.07.28.454245 — genomics — Posted on 2021-07-29

315 Estimating dispersal using close kin dyads: The KINDISPERSE R package

Jasper, M. E.; Hoffmann, A. A.; Schmidt, T. L.

10.1101/2021.07.28.454079 — genetics — Posted on 2021-07-29

316 Evolutionary dynamics of asexual hypermutators adapting to a novel environment

Ho, W.-C.; Behringer, M. G.; Miller, S. F.; Gonzales, J.; Nguyen, A.; Allahwerdy, M.; Boyer, G. F.; Lynch, M.

10.1101/2021.07.28.454222 — evolutionary biology — Posted on 2021-07-29

317 A systematic review and meta-analysis of the potential non-human animal reservoirs and arthropod vectors of the Mayaro virus

Celone, M.; Okech, B.; Han, B. A.; Forshey, B.; Anyamba, A.; Dunford, J.; Rutherford, G.; Mita Mendoza, N. K.; Estallo, E. L.; Khouri, R.; de Siqueira, I. C.; Pollett, S.

10.1101/2021.07.28.454243 — ecology — Posted on 2021-07-29

318 Full-length, single-cell RNA-sequencing of human bone marrow subpopulations reveals hidden complexity

Schmidt, M. O.; Deslattes Mays, A.; Barefoot, M. E.; Riegel, A. T.; Wellstein, A.

10.1101/2021.07.28.454226 — molecular biology — Posted on 2021-07-29

319 PLB-985 neutrophil-like cells release antifungal extracellular vesicles against the human-pathogenic fungus Aspergillus fumigatus

Rafiq, M.; Rivieccio, F.; Zimmermann, A.-K.; Visser, C.; Bruch, A.; Krüger, T.; Gonzalez, K.; Kniemeyer, O.; Blango, M. G.; Brakhage, A. A.

10.1101/2021.07.28.454178 — microbiology — Posted on 2021-07-29

320 Systems analysis of immune responses to attenuated P. falciparum malaria sporozoite vaccination reveals excessive inflammatory signatures correlating with impaired immunity

Du, Y.; Hertoghs, N.; Carnes, J.; McDermott, S. M.; Neal, M. L.; Schwedhelm, K. V.; McElrath, M. J.; De Rosa, S. C.; Aitchison, J. D.; Stuart, K. D.

10.1101/2021.07.28.454252 — immunology — Posted on 2021-07-29

321 Multi-tier mechanics control stromal adaptations in swelling lymph nodes

10.1101/2021.07.28.454217 — immunology — Posted on 2021-07-29

322 TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration

Xie, M.; Liu, Y. U.; Zhao, S.; Zhang, L.; Bosco, D. B.; Pang, Y.-P.; Zhong, J.; Sheth, U.; Martens, Y. A.; Zhao, N.; Liu, C.-C.; Zhuang, Y.; Wang, L.; Dickson, D. W.; Mattson, M. P.; Bu, G.; Wu, L.-J.

10.1101/2021.07.28.454242 — neuroscience — Posted on 2021-07-29

323 Early Life Adversity in Male Mice Sculpts Reward Circuits.

Wendel, K. M.; Short, A. K.; Noarbe, B. P.; Haddad, E.; Palma, A. M.; Yassa, M. A.; Baram, T. Z.; Obenaus, A.

10.1101/2021.07.28.454015 — neuroscience — Posted on 2021-07-29

324 Evaluating the Effect of Semantic Congruency and Valence on Multisensory Integration

Letts, E. G.; Basharat, A.; Barnett-Cowan, M.

10.1101/2021.07.28.454034 — neuroscience — Posted on 2021-07-29

325 Emotional context sculpts action goal representations in the lateral frontal pole

Lapate, R. C.; Ballard, I. C.; Heckner, M. K.; D'Esposito, M.

10.1101/2021.07.28.453895 — neuroscience — Posted on 2021-07-29

326 The timescale and magnitude of aperiodic activity decreases with cortical depth in humans, macaques and mice

Halgren, M.; Kang, R.; Voytek, B.; Ulbert, I.; Fabo, D.; Eross, L. G.; Wittner, L.; Madsen, J.; Doyle, W. K.; Devinsky, O.; Halgren, E.; Harnett, M. T.; Cash, S. S.

10.1101/2021.07.28.454235 — neuroscience — Posted on 2021-07-29

327 Functional connectomics spanning multiple areas of mouse visual cortex

MICrONs Consortium, ; Bodor, A. L.; Halageri, A.; Sterling, A.; Tolias, A. S.; Ramos, A.; Nehoran, B.; Silverman, B.; Celii, B.; Smith, C. L.; Schneider-Mizell, C. M.; Jordan, C.; Xu, C.; Papadopoulos, C.; Gamlin, C.; Kapner, D.; Bumbarger, D. J.; Brittain, D.; Yatsenko, D.; Walker, E. Y.; Miranda, E.; Froudarakis, E.; Mitchell, E.; Cobos, E.; Sinz, F. H.; Ye, F.; Collman, F.; Mahalingam, G.; Williams, G.; Seung, H. S.; Bae, J. A.; Reimer, J.; Hebditch, J.; Gager, J.; Wu, J.; Buchanan, J.; Kuehner, K.; Li, K.; Lee, K.; Willie, K.; Elabbady, L.; Baptiste, M.; Castro, M. A.; Takeno, M.; Moore,

10.1101/2021.07.28.454025 — neuroscience — Posted on 2021-07-29

328 Synaptotagmin 1 oligomerization via the juxtamembrane linker regulates spontaneous and evoked neurotransmitter release

Courtney, K. C.; Li, Y.; Vevea, J. D.; Wu, Z.; Zhang, Z.; Chapman, E. R.

10.1101/2021.07.28.454225 — neuroscience — Posted on 2021-07-29

329 The complete genome of carbapenem-resistant Escherichia coli ST410 harbored blaNDM-5 isolated from reservoir water in Singapore.

Zhong, Y.; Guo, S.; Hong Ming, G. O.; Schlundt, J.

10.1101/2021.07.28.454241 — pathology — Posted on 2021-07-29

330 Predictive modeling reveals that higher-order cooperativity drives transcriptional repression in a synthetic developmental enhancer

Kim, Y. J.; Rhee, K.; Liu, J.; Jeammet, P.; Turner, M. A.; Small, S.; Garcia, H. G.

10.1101/2021.07.28.454075 — biophysics — Posted on 2021-07-29

331 Prediction of DNA from context using neural networks

Gronbaek, C.; Liang, Y.; Elliott, D.; Krogh, A.

10.1101/2021.07.28.454211 — bioinformatics — Posted on 2021-07-29

332 Surface electric fields increase human osteoclast resorption through improved wettability on carbonate-incorporated apatite

Muguruza, L. B.; Makela, K.; Yrjala, T.; Salonen, J.; Yamashita, K.; Nakamura, M.

10.1101/2021.07.28.454035 — bioengineering — Posted on 2021-07-29

333 Long term conservation of DNA at ambient temperature. Implications for DNA data storage

Coudy, D.; Colotte, M.; Luis, A.; Tuffet, S.; Bonnet, J.

10.1101/2021.07.28.454193 — biochemistry — Posted on 2021-07-29

334 Single cell analysis of endometriosis reveals a coordinated transcriptional program driving immunotolerance and angiogenesis across eutopic and ectopic tissues.

Tan, Y.; Flynn, W. F.; Sivajothi, S.; Luo, D.; Bozal, S.; Luciano, A. A.; Robson, P.; Luciano, D. E.; Courtois, E. T.

10.1101/2021.07.28.453839 — genomics — Posted on 2021-07-29

335 An atlas of healthy and injured cell states and niches in the human kidney

Lake, B. B.; Menon, R.; Winfree, S.; Hu, Q.; Ferreira, R. M.; Kalhor, K.; Barwinska, D.; Otto, E. A.; Ferkowicz, M.; Diep, D.; Plongthongkum, N.; Knoten, A.; Urata, S.; Naik, A. S.; Eddy, S.; Zhang, B.; Wu, Y.; Salamon, D.; Williams, J. C.; Wang, X.; Balderrama, K. S.; Hoover, P.; Murray, E.; Vijayan, A.; Chen, F.; Waikar, S. S.; Rosas, S.; Wilson, F. P.; Palevsky, P. M.; Kiryluk, K.; Sedor, J. R.; Toto, R. D.; Parikh, C.; Kim, E. H.; Macosko, E. Z.; Kharchenko, P. V.; Gaut, J. P.; Hodgin, J. B.; Eadon, M. T.; Dagher, P. C.; El-Achkar, T. M.; Zhang, K.; Kretzler, M.; Jain, S.; KPMP Consortium,

10.1101/2021.07.28.454201 — genomics — Posted on 2021-07-29

336 Inferring the intrinsic mutational fitness landscape of influenza-like evolving antigens from temporally ordered sequence data

Doelger, J.; Kardar, M.; Chakraborty, A. K.

10.1101/2021.07.28.454153 — evolutionary biology — Posted on 2021-07-29

337 Ethanol pre-exposure enhances alcohol-seeking behavior at cellular level by chemoattraction and exhibits bleb-driven cellular stress response in uniform ethanol concentration

Kar, N.; Bellare, J.

10.1101/2021.07.28.454082 — cell biology — Posted on 2021-07-29

338 Exploratory extracellular vesicle-bound miRNA profiling to identify candidate biomarkers of chronic alcohol drinking in non-human primates

Lewis, S. A.; Doratt, B.; Sureshchandra, S.; Pan, T.; Gonzalez, S. W.; Shen, W.; Grant, K. A.; Messaoudi, I.

10.1101/2021.07.28.454223 — molecular biology — Posted on 2021-07-29

339 Molecular surveillance of zoonotic bacterial pathogens in farm dwelling peridomestic rodents across the upper Midwest, USA

Jahan, N. A.; Lindsey, L. L.; Kipp, E. J.; Heins, B. J.; Runck, A. M.; Larsen, P. A.

10.1101/2021.07.28.454187 — microbiology — Posted on 2021-07-29

340 Insights from spatial measures of intolerance to identify pathogenic variants in developmental and epileptic encephalopathies

Silk, M.; De Sa, A.; Olshansky, M.; Ascher, D. B.

10.1101/2021.07.28.454182 — neuroscience — Posted on 2021-07-29

341 Single voxel autocorrelation uncovers gradients of temporal dynamics in the hippocampus and entorhinal cortex during rest and navigation

Bouffard, N. R.; Golestani, A. R.; Brunec, I. K.; Bellana, B.; Barense, M. D.; Moscovitch, M.

10.1101/2021.07.28.454036 — neuroscience — Posted on 2021-07-29

342 Sensory computations in the cuneate nucleus of macaques

Suresh, A. K.; Greenspon, C. M.; He, Q.; Rosenow, J. M.; Miller, L. E.; Bensmaia, S. J.

10.1101/2021.07.28.454185 — neuroscience — Posted on 2021-07-29

343 Developmental coupling of cerebral blood flow and fMRI fluctuations in youth

Baller, E. B.; Valcarcel, A. M.; Adebimpe, A.; Alexander-Bloch, A.; Cui, Z.; Gur, R. C.; Gur, R. E.; Larsen, B. L.; Linn, K. A.; O'Donnell, C. M.; Pines, A. R.; Raznahan, A.; Roalf, D. R.; Sydnor, V. J.; Tapera, T. M.; Tisdall, M. D.; Vandekar, S.; Xia, C. H.; Detre, J. A.; Shinohara, R. T.; Satterthwaite, T. D.

10.1101/2021.07.28.454179 — neuroscience — Posted on 2021-07-29

344 Chemogenetic Inhibition of Corticostriatal Circuits Reduces Cued Reinstatement of Methamphetamine Seeking

Kearns, A. M.; Siemsen, B.; Hopkins, J.; Weber, R.; Scofield, M.; Peters, J.; Reichel, C. M.

10.1101/2021.07.28.453847 — neuroscience — Posted on 2021-07-29

345 Pharmacokinetics and biodistribution of extracellular vesicles administered intravenously and intranasally to Macaca nemestrina

Driedonks, T.; Jiang, L.; Carlson, B.; Han, Z.; Liu, G.; Queen, S. E.; Shirk, E. N.; Gololobova, O.; Nyberg, L.; Lima, G.; Schonvisky, K.; Stover, M.; Guerrero-Martin, S.; Richardson, M. R.; Smith, B.; Lai, C. P.; Izzi, J. M.; Hutchinson, E. K.; Pate, K. A.; Witwer, K. W.

10.1101/2021.07.28.454192 — pharmacology and toxicology — Posted on 2021-07-29

346 Transgenic expression of Nix converts genetic females into males and allows automated sex sorting in Aedes albopictus

Lutrat, C.; Olmo, R. P.; Baldet, T.; Bouyer, J.; Marois, E.

10.1101/2021.07.28.454191 — bioengineering — Posted on 2021-07-29

347 Modeling habitat suitability of vulnerable Mollucan Babirusa Babyrousa babyrussa in small island of Buru, Indonesia

Wibowo, A. A.

10.1101/2021.07.28.454166 — ecology — Posted on 2021-07-29

348 In situ cryo-electron tomography reveals local cellular machineries for axon branch development

Nedozralova, H.; Basnet, N.; Ibiricu, I.; Bodakuntla, S.; Biertumpfel, C.; Mizuno, N.

10.1101/2021.07.28.454169 — neuroscience — Posted on 2021-07-29

349 Cross-species comparison of human and rodent primary reward consumption under budget constraints

Hu, Y.; Nitsch, F. J.; van Wingerden, M.; Kalenscher, T.

10.1101/2021.07.28.454138 — neuroscience — Posted on 2021-07-29

350 Muscarinic receptors mediate motivation via preparatory neural activity in humans

Grogan, J. P.; Raemaekers, M.; van Swieten, M. M. H.; Green, A. L.; Gillies, M. J.; Manohar, S. G.

10.1101/2021.07.28.454154 — neuroscience — Posted on 2021-07-29

351 Patient-derived gene and protein expression signatures of NGLY1 deficiency

Rauscher, B.; Mueller, W. F.; Clauder-Muenster, S.; Jakob, P.; Islam, M. S.; Sun, H.; Ghidelli-Disse, S.; Boesche, M.; Bantscheff, M.; Pflaumer, H.; Collier, P.; Haase, B.; Chen, S.; Wang, G.; Benes, V.; Snyder, M.; Drewes, G.; Steinmetz, L. M.

10.1101/2021.07.28.453930 — systems biology — Posted on 2021-07-29

352 Patient-specific Boolean models of signaling networks guide personalized treatments

Montagud, A.; Beal, J.; Tobalina, L.; Traynard, P.; Subramanian, V.; Szalai, B.; Alföldi, R.; Puskas, L.; Valencia, A.; Barillot, E.; Saez-Rodriguez, J.; Calzone, L.

10.1101/2021.07.28.454126 — systems biology — Posted on 2021-07-29

353 Characterization of peptide-protein relationships in protein ambiguity groups via bipartite graphs

Schork, K.; Turewicz, M.; Uszkoreit, J.; Rahnenführer, J.; Eisenacher, M.

10.1101/2021.07.28.454128 — bioinformatics — Posted on 2021-07-29

354 Precision Autism: Genomic Stratification of Disorders Making Up the Broad Spectrum May Demystify its "Epidemic Rates"

Torres, E. B.

10.1101/2021.07.28.454081 — genomics — Posted on 2021-07-29

355 4D live-cell imaging of microgametogenesis in the human malaria parasite Plasmodium falciparum

Yahiya, S.; Jordan, S.; Smith, H. X.; Gaboriau, D. C. A.; Famodimu, M. T.; Dahalan, F. A.; Churchyard, A.; Ashdown, G. W.; Baum, J.

10.1101/2021.07.28.454129 — microbiology — Posted on 2021-07-29

356 Brain connectivity-based prediction of real-life creativity is mediated by semantic memory structure

Ovando-Tellez, M.; Kenett, Y. N.; Benedek, M.; Bernard, M.; Belo, J.; Beranger, B.; Bieth, T.; VOLLE, E.

10.1101/2021.07.28.453991 — neuroscience — Posted on 2021-07-29

357 Construction of transcript regulation mechanism prediction models based on binding motif environment of transcription factor AoXlnR in Aspergillus oryzae

Oka, H.; KOJIMA, T.; Kato, R.; Ihara, K.; Nakano, H.

10.1101/2021.07.28.454268 — genomics — Posted on 2021-07-29

358 Recent SIV-Macaque Trials: A Reassessment of Immune Priming and Varying Infectability in Repeated Low-dose Challenge Studies

Spouge, J. L.

10.1101/2021.07.28.454270 — microbiology — Posted on 2021-07-29

359 Reliability of Mouse Behavioural Tests of Anxiety: a Systematic Review and Meta-Analysis on the Effects of Anxiolytics.

Rosso, M.; Wirz, R.; Loretan, A. V.; Sutter, N. A.; Pereira da Cunha, C. T.; Jaric, I.; Würbel, H.; Voelkl, B.

10.1101/2021.07.28.454267 — neuroscience — Posted on 2021-07-29

360 Building the Mega Single Cell Transcriptome Ocular Meta-Atlas

Swamy, V. S.; Fufa, T. D.; Hufnagel, R. B.; McGaughey, D. M.

10.1101/2021.03.26.437190 — bioinformatics — Posted on 2021-07-29

361 SUITOR: selecting the number of mutational signatures through cross-validation

Lee, D.; Wang, D.; Yang, X. R.; Shi, J.; Landi, M. T.; Zhu, B.

10.1101/2021.07.28.454269 — bioinformatics — Posted on 2021-07-29

362 Direct comparison of contralateral bias and face/scene selectivity in human occipitotemporal cortex

Silson, E. H.; Groen, I. I. A.; Baker, C. I.

10.1101/2021.05.06.442603 — neuroscience — Posted on 2021-07-29

363 Knowledge Graph-based Recommendation Framework Identifies Novel Drivers of Resistance in EGFR mutant Non-small Cell Lung Cancer

Gogleva, A.; Polychronopoulos, D.; Pfeifer, M.; Poroshin, V.; Ughetto, M.; Sidders, B.; Dry, J.; Ahdesmaki, M.; McDermott, U.; Papa, E.; Bulusu, K.

10.1101/2021.07.23.453506 — cancer biology — Posted on 2021-07-29

364 Recirculation of H2, CO2, and ethylene improves carbon fixation and carboxylate yields in anaerobic fermentation

Baleeiro, F. C. F.; Kleinsteuber, S.; Sträuber, H.

10.1101/2021.06.11.448067 — bioengineering — Posted on 2021-07-29

365 CLEMSite, a software for automated phenotypic screens using light microscopy and FIB-SEM

Serra Lleti, J. M.; Steyer, A. M.; Schieber, N. L.; Neumann, B.; Tischer, C.; Hilsenstein, V.; Holtstrom, M.; Unrau, D.; Kirmse, R.; Lucocq, J. M.; Pepperkok, R.; Schwab, Y.

10.1101/2021.03.19.436113 — cell biology — Posted on 2021-07-29

366 Plasticity of the dopaminergic phenotype and of locomotion in larval zebrafish induced by changes in brain excitability during the embryonic period

Bataille, S.; Jalaber, H.; Colin, I.; Remy, D.; Affaticati, P.; Froc, C.; Vernier, P.; Demarque, M.

10.1101/2021.07.19.452915 — neuroscience — Posted on 2021-07-29

367 Mapping drug-microenvironment-genetic interplay in CLL reveals trisomy 12 as a modulator of microenvironmental signals

Bruch, P.-M.; Giles, H. A. R.; Kolb, C.; Herbst, S. A.; Becirovic, T.; Roider, T.; Lu, J.; Scheinost, S.; Wagner, L.; Hüllein, J.; Berest, I.; Kriegsmann, M.; Kriegsmann, K.; Zgorzelski, C.; Dreger, P.; Zaugg, J. B.; Müller-Tidow, C.; Zenz, T.; Huber, W.; Dietrich, S.

10.1101/2021.07.23.453514 — cancer biology — Posted on 2021-07-29

368 Symmetry and simplicity spontaneously emerge from the algorithmic nature of evolution

Johnston, I.; Dingle, K.; Greenbury, S. F.; Camargo, C. Q.; Doye, J. P. K.; Ahnert, S. E.; Louis, A. A.

10.1101/2021.07.28.454038 — evolutionary biology — Posted on 2021-07-29

369 Inhibition of Mul1-mediated ubiquitination promotes mitochondria-associated translation

Gao, Y.; Cardamone, M. D.; Kwan, J.; Hekman, R.; Orofino, J.; Lyons, S. M.; Emili, A.; Perissi, V.

10.1101/2021.07.28.454107 — cell biology — Posted on 2021-07-29

370 SYNAPTIC RELEASE POTENTIATION AT AGING AUDITORY RIBBON SYNAPSES

Peineau, T.; Belleudy, S.; pietropaolo, s.; bouleau, y.; Dulon, D.

10.1101/2020.05.15.097550 — neuroscience — Posted on 2021-07-29

371 Contribution of 3D genome topological domains to genetic risk of cancers

Jablonski, K. P.; Carron, L.; Mozziconacci, J.; Forne, T.; Hütt, M.-T.; Lesne, A.

10.1101/2021.07.26.453813 — genetics — Posted on 2021-07-29

372 PRDM9 losses in vertebrates are coupled to those of paralogs ZCWPW1 and ZCWPW2

Cavassim, M. I. A.; Baker, Z.; Hoge, C.; Schierup, M.; Schumer, M.; Przeworski, M.

10.1101/2021.06.08.447603 — evolutionary biology — Posted on 2021-07-29

373 In vivo KRAS G12D/V Degradation Mediated by CANDDY Using a Modified Proteasome Inhibitor

Imanishi, S.; Huang, L.; Itakura, S.; Ishizaka, M.; Iwasaki, Y.; Yamaguchi, T.; Miyamoto-Sato, E.

10.1101/2021.04.23.441075 — molecular biology — Posted on 2021-07-29

374 Fecal Microbiota Transplantation Drives Colonic Expression of Immune Activation Genes in a Mouse Model of Antibiotic Use

Moreau, G. B.; Ozbek, H.; Kumar, P.; Frisbee, A.; Leslie, J. L.; Petri, W. A.

10.1101/2021.07.23.453497 — microbiology — Posted on 2021-07-29

375 Lytic transglycosylases mitigate periplasmic crowding by degrading soluble cell wall turnover products

Weaver, A. I.; Alvarez, L.; Rosch, K. M.; Ahmed, A.; Wang, G. S.; VanNieuwenzhe, M. S.; Cava, F.; Doerr, T.

10.1101/2021.07.27.453986 — microbiology — Posted on 2021-07-29

376 Functional and comparative genomics reveals conserved noncoding sequences in the nitrogen-fixing clade

Pereira, W. J.; Knaack, S. A.; Conde, D.; Chakraborty, S.; Folk, R. A.; Triozzi, P. M.; Balmant, K. M.; Dervinis, C.; Schmidt, H. W.; Ane, J.-M.; Roy, S.; Kirst, M.

10.1101/2021.07.27.453985 — plant biology — Posted on 2021-07-29

377 Cryo-EM single particle structure refinement and map calculation using Servalcat

Yamashita, K.; Palmer, C. M.; Burnley, T.; Murshudov, G. N.

10.1101/2021.05.04.442493 — biophysics — Posted on 2021-07-29

378 Visualizing Amino Acid Substitutions in a Physicochemical Vector Space

Nemzer, L. R.

10.1101/2021.07.15.452549 — bioinformatics — Posted on 2021-07-29

379 Generalizability in White Blood Cells' Classification Problem

Tavakoli, S.; Ghaffari, A.; Mousavi Kouzehkanan, Z.

10.1101/2021.05.12.443717 — bioengineering — Posted on 2021-07-28

380 Protein Kinase C gamma Mutations Drive Spinocerebellar Ataxia Type 14 by Impairing Autoinhibition

Pilo, C. A.; Baffi, T. R.; Kornev, A. P.; Kunkel, M. T.; Malfavon, M.; Chen, D.-H.; Huang, L.-C.; Longman, C.; Kannan, N. A.; Raskind, W. H.; Gonzalez, D. J.; Taylor, S. S.; Gorrie, G.; Newton, A. C.

10.1101/2021.06.24.449810 — biochemistry — Posted on 2021-07-29

381 The whale shark genome reveals patterns of vertebrate gene family evolution

Tan, M.; Redmond, A.; Dooley, H.; Nozu, R.; Sato, K.; Kuraku, S.; Koren, S.; Phillippy, A.; Dove, A.; Read, T.

10.1101/685743 — genomics — Posted on 2021-07-28

382 SpotClean adjusts for spot swapping in spatial transcriptomics data

Ni, Z.; Prasad, A.; Chen, S.; Halberg, R. B.; Arkin, L.; Drolet, B.; Newton, M.; Kendziorski, C.

10.1101/2021.06.11.448105 — genomics — Posted on 2021-07-28

383 Identification of deleterious single nucleotide polymorphism (SNP)s on the human TBX5 gene & prediction of their structural & functional consequences: An in silico approach

Mahfuz, A. M. U. B.; Khan, M. A.

10.1101/2020.05.16.099648 — genetics — Posted on 2021-07-29

384 Natural selection and the advantage of recombination

Gerrish, P. J.; Galeota-Sprung, B.; Cordero, F.; Sniegowski, P. D.; Colato, A.; Hengartner, N. W.; Vejalla, V.; Chevalier, J.; Ycart, B.

10.1101/2020.08.28.271486 — evolutionary biology — Posted on 2021-07-28

385 Natural selection promotes the evolution of recombination 2: during the process of natural selection

Gerrish, P. J.; Cordero, F.; Galeota-Sprung, B.; Colato, A.; Vejalla, V.; Sniegowski, P. D.; Hengartner, N. W.

10.1101/2021.06.07.447324 — evolutionary biology — Posted on 2021-07-29

386 Extracting spatial networks from capture-recapture data reveal structured habitat use within a marine mammal's spatial range

Bonnell, T.; Michaud, R.; Dupuch, A.; Lesage, V.; Chion, C.

10.1101/2021.05.06.442957 — ecology — Posted on 2021-07-29

387 Host species identity shapes the diversity and structure of insect microbiota

Malacrino', A.

10.1101/2021.07.19.452888 — ecology — Posted on 2021-07-29

388 Inferring kinetic parameters of oscillatory gene regulation from single cell time series data

Burton, J.; Manning, C. S.; Rattray, M.; Papalopulu, N.; Kursawe, J.

10.1101/2021.05.12.443895 — developmental biology — Posted on 2021-07-28

389 Cortical actin flow activates an alpha-catenin clutch to assemble adherens junctions

Noordstra, I.; Diez Hermoso, M.; Schimmel, L.; Bonfim-Melo, A.; Kalappurakkal, J. M.; Mayor, S.; Gordon, E.; Roca-Cusachs, P.; Yap, A. S.

10.1101/2021.07.28.454239 — cell biology — Posted on 2021-07-28

390 The ER membrane chaperone Shr3 acts in a progressive manner to assist the folding of related plasma membrane transport proteins

Myronidi, I.; Ring, A.; Ljungdahl, P. O.

10.1101/2020.07.05.188557 — cell biology — Posted on 2021-07-28

391 Comparing cortex-wide gene expression patterns between species in a common reference frame

englund, m.; James, S. S.; Bottom, R.; Huffman, K.; Wilson, S. P.; Krubitzer, L.

10.1101/2021.07.28.454203 — neuroscience — Posted on 2021-07-28

392 The KH domains of FMRP differentially regulate neuronal granule formation, dynamics, and function in Drosophila

Starke, E. L.; Barbee, S. A.

10.1101/2021.06.01.446613 — neuroscience — Posted on 2021-07-28

393 Interhemispheric Connectivity Supports Load-Dependent Working Memory Maintenance for Complex Visual Stimuli

Reichert Plaska, C.; Ortega, J.; Gomes, B. A.; Ellmore, T. M.

10.1101/2021.03.24.436845 — neuroscience — Posted on 2021-07-28

394 A Discriminative Characterization of Heschl's Gyrus Morphology using Spectral Graph Features

Maghsadhagh, S.; Dalboni da Rocha, J. L.; Benner, J.; Schneider, P.; Golestani, N.; Behjat, H.

10.1101/2021.05.04.442618 — neuroscience — Posted on 2021-07-28

395 The optimal spatial arrangement of ON and OFF receptive fields

Jun, N. Y.; Field, G. D.; Pearson, J. M.

10.1101/2021.03.10.434612 — neuroscience — Posted on 2021-07-28

396 An altered balance of integrated and segregated brain activity is a marker of cognitive deficits following sleep deprivation

Cross, N.; Pomares, F. B.; Nguyen, A.; Perrault, A. A.; Jegou, A.; Uji, M.; Lee, K.; Razavipour, F.; Ali, O. B. K.; Aydin, U.; Benali, H.; Grova, C.; Dang-Vu, T. T.

10.1101/2020.11.28.402305 — neuroscience — Posted on 2021-07-28

397 Cognitive, synaptic and neuropathological changesin Alzheimer's brain-inoculated mice

Lam, S.; Boluda, S.; Herard, A. S.; Petit, F.; Eddarkaoui, S.; Cambon, K.; Picq, J. L.; Buee, L.; Duyckaerts, C.; Haik, S.; Dhenain, M.

10.1101/2021.04.06.438654 — neuroscience — Posted on 2021-07-28

398 The universal language network: A cross-linguistic investigation spanning 45 languages and 11 language families.

Ayyash, D.; Malik-Moraleda, S.; Gallee, J.; Affourtit, J.; Hoffman, M.; Mineroff, Z.; Jouravlev, O.; Fedorenko, E.

10.1101/2021.07.28.454040 — neuroscience — Posted on 2021-07-29

399 An improved fluorescent noncanonical amino acid for measuring conformational distributions using time-resolved transition metal ion FRET

Zagotta, W. N.; Sim, B. S.; Nhim, A. K.; Raza, M. M.; Evans, E. G.; Venkatesh, Y.; Jones, C. M.; Mehl, R. A.; Petersson, J.; Gordon, S. E.

10.1101/2021.05.10.443484 — biophysics — Posted on 2021-07-28

400 DynaMorph: self-supervised learning of morphodynamic states of live cells

Wu, Z.; Chhun, B. B.; Popova, G.; Guo, S.-M.; Kim, C.; Yeh, L.-H.; Nowakowski, T. J.; Zou, J.; Mehta, S. B.

10.1101/2020.07.20.213074 — bioinformatics — Posted on 2021-07-28

401 Functional Inference of Gene Regulation using Single-Cell Multi-Omics

Kartha, V. K.; Duarte, F. M.; Hu, Y.; Ma, S.; Chew, J. G.; Lareau, C. A.; Earl, A.; Burkett, Z.; Kohlway, A. S.; Lebofski, R.; Buenrostro, J. D.

10.1101/2021.07.28.453784 — genomics — Posted on 2021-07-28

402 Genetic architecture of a mutation's expressivity

Schell, R.; Hale, J. J.; Mullis, M. N.; Matsui, T.; Foree, R.; Ehrenreich, I. M.

10.1101/2020.04.03.024547 — genetics — Posted on 2021-07-28

403 Natural variations in reproductive timing of brood size and X-chromosome nondisjunction in Caenorhabditis elegans

Lim, J.; Kim, J.; Lee, J.

10.1101/2021.04.08.439028 — genetics — Posted on 2021-07-28

404 We get by with a little help from our friends: diversity begets diversity through shared adaptive genetic variation

Richards, E.; Martin, C. H.

10.1101/2021.07.01.450755 — evolutionary biology — Posted on 2021-07-28

405 Natural selection promotes the evolution of recombination 1: between the products of natural selection

Gerrish, P. J.; Galeota-Sprung, B. J.; Sniegowski, P. D.; Chevallier, J.; Ycart, B.

10.1101/2021.06.07.447320 — evolutionary biology — Posted on 2021-07-28

406 Chromatin-contact atlas reveals disorder-mediated protein interactions and moonlighting chromatin-associated RBPs

Rafiee, M.-r.; Zagalak, J.; Sidorov, S.; Steinhauser, S.; Davey, K.; Ule, J.; Luscombe, N. M.

10.1101/2020.07.13.200212 — molecular biology — Posted on 2021-07-28

407 The Gut Microbiome of Exudivorous Wild and non-Wild Marmosets

Malukiewicz, J.; Cartwright, R. A.; Dergam, J. A.; Igayara, C. S.; Kessler, S.; Moreira, S. B.; Nash, L. T.; Nicola, P. A.; Pereira, L. C. M.; Pissinati, A.; Ruiz-Miranda, C. R.; Ozga, A. T.; Quirino, A. A.; Roos, C.; Silva, D. L.; Stone, A. C.; Grativol, A. D.

10.1101/708255 — microbiology — Posted on 2021-07-28

408 Mitochondria dysfunction in Charcot Marie Tooth 2B Peripheral Sensory Neuropathy

Gu, Y.; Guerra, F.; Hu, M.; Pope, A.; Sung, K.; Yang, W.; Jetha, S.; Shoff, T. A.; Gunatilake, T.; Dahlkamp, O.; Shi, L. Z.; Manganelli, F.; Nolano, M.; Zhou, Y.; Ding, J.; Bucci, C.; Wu, C.

10.1101/2021.07.28.454213 — neuroscience — Posted on 2021-07-28

409 The fasciola cinereum subregion of the hippocampus is important for the acquisition of visual contextual memory

Park, S.-B.; Lee, E.-Y.; Lim, H.-Y.; Yoo, S.-W.; Lee, E.; Jung, H.-S.; Sun, W.; Lee, I.

10.1101/748301 — neuroscience — Posted on 2021-07-28

410 Reward Enhances Connectivity between the Ventral Striatum and the Default Mode Network

Dobryakova, E.; Smith, D. V.

10.1101/2021.07.28.454086 — neuroscience — Posted on 2021-07-28

411 Detecting changes in dynamical structures in synchronous neural oscillations using probabilistic inference

Yokoyama, H.; Kitajo, K.

10.1101/2020.10.13.335356 — neuroscience — Posted on 2021-07-28

412 Structuring time: The hippocampus constructs sequence memories that generalize temporal relations across experiences

Bellmund, J. L. S.; Deuker, L.; Montijn, N. D.; Doeller, C. F.

10.1101/2021.04.23.440002 — neuroscience — Posted on 2021-07-28

413 Dopaminergic mechanisms underlying the expression of antipsychotic-induced dopamine supersensitivity in rats

Servonnet, A.; Allain, F.; Gravel-Chouinard, A.; Hernandez, G.; Bourdeau Caporuscio, C.; Legrix, M.; Levesque, D.; Rompre, P.-P.; Samaha, A.-N.

10.1101/2020.09.08.287664 — pharmacology and toxicology — Posted on 2021-07-28

414 An active RNA transport mechanism into plant vacuoles

Floyd, B. E.; Kazibwe, Z.; Morriss, S. C.; Mugume, Y.; Liu, A.-Y.; Ridout, V.; Luo, X.; MacIntosh, G. C.; Bassham, D. C.

10.1101/2021.07.28.454214 — plant biology — Posted on 2021-07-28

415 An open state of a voltage-gated sodium channel involving a π-helix and conserved pore-facing Asparagine

Choudhury, K.; Kasimova, M.; McComas, S.; Howard, R. J.; Delemotte, L.

10.1101/2021.07.28.454140 — biophysics — Posted on 2021-07-28

416 Machine Learning of Pseudomonas aeruginosa transcriptomes identifies independently modulated sets of genes associated with known transcriptional regulators

Rajput, A.; Tsunemoto, H.; Sastry, A. V.; Szubin, R.; Rychel, K.; Sugie, J.; Pogliano, J.; Palsson, B.

10.1101/2021.07.28.454220 — bioinformatics — Posted on 2021-07-28

417 Comparative analysis of single nucleotide polymorphisms and microsatellite markers for parentage verification and discovery within the equine Thoroughbred breed

Flynn, P.; Morrin-O'Donnell, R.; Weld, R.; Gargan, L. M.; Carlsson, J.; Daly, S.; Suren, H.; Siddavatam, P.; Gujjula, K. R.

10.1101/2021.07.28.453868 — genetics — Posted on 2021-07-28

418 Killer Knots: Molecular evolution of Inhibitor Cystine Knot toxins in wandering spiders (Araneae: Ctenidae)

Cole, T. J.; Brewer, M. S.

10.1101/2021.07.28.453581 — evolutionary biology — Posted on 2021-07-28

419 Environmental drivers of body size in North American bats

Alston, J. M.; Keinath, D. A.; Willis, C. K. R.; Lausen, C. L.; O'Keefe, J. M.; Tyburec, J.; Broders, H. G.; Moosman, P. R.; Carter, T. C.; Chambers, C. L.; Gillam, E. H.; Geluso, K.; Weller, T. J.; Burles, D.; Fletcher, Q. E.; Norquay, K. J.; Goheen, J. R.

10.1101/2021.07.28.454183 — ecology — Posted on 2021-07-28

420 Selective Requirement for Polycomb Repressor Complex 2 in the Generation of Specific Hypothalamic Neuronal Sub-types

Thor, S. S.; Salmani, B. Y.; Balderson, B.; Bauer, S.; Ekman, H.; Starkenberg, A.; Perlmann, T.; Piper, M.; Boden, M.

10.1101/2021.07.28.454060 — developmental biology — Posted on 2021-07-28

421 Annexin A1 is a polarity cue that directs planar mitotic spindle orientation during mammalian epithelial morphogenesis

Fankhaenel, M.; Golestan Hashemi, F. S.; Hosawi, M. M.; Mourao, L.; Skipp, P.; Morin, X.; Scheele, C. L.; Elias, S.

10.1101/2021.07.28.454117 — cell biology — Posted on 2021-07-28

422 Calcium/Calmodulin Dependent Protein Kinase Kinase 2 Regulates the Expansion of Tumor-induced Myeloid-Derived Suppressor Cells

Huang, W.; Liu, Y.; Luz, A.; Berrong, M.; Meyer, J.; Zou, Y.; Swann, E.; Sundaramoorthy, P.; Kang, Y.; Jauhari, S.; Lento, W.; Chao, N.; Racioppi, L.

10.1101/2021.07.28.454009 — immunology — Posted on 2021-07-28

423 Submandibular Injection of Indoleamine 2,3-Dioxygenase Galectin-3 Fusion Protein Inhibits and Prevents Periodontal Disease Progression Over 12 Weeks

Rocha, F.; Graves, C.; Altitinchi, A.; Farhadi, S. A.; Macias, S. L.; Wanchoo, A.; Hudalla, G. A.; Keselowsky, B. G.; Wallet, S. M.

10.1101/2021.07.28.454186 — immunology — Posted on 2021-07-28

424 The neuropeptide Pth2 modulates social behavior and anxiety in zebrafish

Anneser, L.; Gemmer, A.; Eilers, T.; Alcantara, I. C.; Loos, A.-Y.; Ryu, S.; Schuman, E.

10.1101/2021.07.28.454115 — neuroscience — Posted on 2021-07-28

425 Identification of cells expressing Calcitonins A and B, PDF and ACP in Locusta migratoria using cross-reacting antisera and in situ hybridization

Veenstra, J. A.

10.1101/2021.07.28.454216 — neuroscience — Posted on 2021-07-28

426 Developmentally-regulated impairment of parvalbumin interneuron synaptic transmission in an experimental model of Dravet syndrome

Kaneko, K.; Currin, C. B.; Goff, K. M.; Somarowthu, A.; Vogels, T. P.; Goldberg, E. M.

10.1101/2021.07.28.454042 — neuroscience — Posted on 2021-07-28

427 Cell-specific Bioorthogonal Tagging of Glycoproteins in Co-culture

Cioce, A.; Calle, B.; Marchesi, A.; Bineva-Todd, G.; Flynn, H.; Li, Z.; Tastan, O. Y.; Roustan, C.; Keenan, T.; Both, P.; Huang, K.; Parmeggiani, F.; Snijders, A. P.; Kjaer, S.; Fascione, M. A.; Flitsch, S. L.; Schumann, B.

10.1101/2021.07.28.454135 — synthetic biology — Posted on 2021-07-28

428 Transparency in peer review: Exploring the content and tone of reviewers' confidential comments to editors

O'Brien, B. C.; Artino, A. R.; Costello, J. A.; Driessen, E.; Maggio, L. A.

10.1101/2021.07.28.454037 — scientific communication and education — Posted on 2021-07-28

429 Perception of structurally distinct effectors by the integrated WRKY domain of a plant immune receptor.

Mukhi, N.; Brown, H.; Gorenkin, D.; Ding, P.; Bentham, A. R.; Jones, J. D.; Banfield, M. J.

10.1101/2021.07.28.454147 — plant biology — Posted on 2021-07-28

430 CRISPR-Cas9 Screen Reveals PSMB3 Contributes to Gliomagenesis Through Proteasome-Dependent and Independent Mechanisms

Baisiwala, S.; Budhiraja, S.; Zolp, A.; Nandoliya, K.; Chen, L.; Park, C.; Perrault, E.; Saathoff, M.; Dmello, C.; Shireman, J.; Lin, P.; Dara, G.; McCortney, K.; Horbinski, C.; Sonabend, A.; Ahmed, A. U.

10.1101/2021.07.28.453566 — cancer biology — Posted on 2021-07-28

431 Chromatin Patterns Distinguish Breast Tumor Subtypes and Disease Progression in Association with ANP32E levels

Ruff, G. L.; Murphy, K. E.; Vertino, P. M.; Murphy, P. J.

10.1101/2021.07.28.454151 — cancer biology — Posted on 2021-07-28

432 Keratin 19 interacts with GSK3β to regulate its nuclear accumulation and degradation of cyclin D3

Sharma, P.; Tiufekchiev, S.; Lising, V.; Chung, S. W.; Suk, J. S.; Chung, B. M.

10.1101/2021.07.28.454205 — cancer biology — Posted on 2021-07-28

433 Retinal vibrations in bacteriorhodopsin are mechanically harmonic but electronically anharmonic: evidence from overtone and combination bands

Lorenz-Fonfria, V. A.; Yagi, K.; Ito, S.; Kandori, H.

10.1101/2021.07.28.454158 — biophysics — Posted on 2021-07-28

434 Development of lipidoid nanoparticles for siRNA delivery to neural cells

Khare, P.; Dave, K. M.; Kamte, Y. S.; Manoharan, M. A.; O'Donnell, L. A.; Manickam, D. S.

10.1101/2021.07.28.454207 — bioengineering — Posted on 2021-07-28

435 Catalytic cycling of human mitochondrial Lon protease

Mohammed, I.; Schmitz, K. A.; Schenck, N.; Topitsch, A.; Maier, T.; Abrahams, J. P.

10.1101/2021.07.28.454137 — biochemistry — Posted on 2021-07-28

436 Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization

Islam, K.; Wagner, S.; Ghosh, A.; Sudhamalla, B.; Jnawali, H. N.; Debiec, R.; Fedorov, E.

10.1101/2021.07.28.453719 — biochemistry — Posted on 2021-07-28

437 The epithelial-specific ER stress sensor IRE1β enables host-microbiota crosstalk to affect colon goblet cell development

Grey, M. J.; De Luca, H.; Ward, D. V.; Kreulen, I. A. M.; Foley, S. E.; Thiagarajah, J. R.; McCormick, B. A.; Turner, J. R.; Lencer, W. I.

10.1101/2021.07.28.453864 — cell biology — Posted on 2021-07-28

438 The human nose organoid respiratory virus model: an ex-vivo human challenge model to study RSV and SARS-CoV-2 pathogenesis and evaluate therapeutics

Rajan, A.; Weaver, A. M.; Alosio, G. M.; Jelinski, J.; Johnson, H. L.; Venable, S. F.; McBride, T.; Aideyan, L.; Piedra, F.-A.; Ye, X.; Melicoff-Portillo, E.; Yerramilli, M. R. K.; Zeng, X.-L.; Mancini, M. A.; Stossi, F.; Maresso, A. W.; Kotkar, S. A.; Estes, M. K.; Blutt, S.; Avadhanula, V.; Piedra, P. A.

10.1101/2021.07.28.453844 — microbiology — Posted on 2021-07-28

439 A repurposed, non-canonical cytochrome c, chaperones calcium binding by PilY1 for type IVa pili formation

Herfurth, M.; Treuner-Lange, A.; Glatter, T.; Wittmaack, N.; Hoiczyk, E.; Pierik, A. J.; Sogaard-Andersen, L.

10.1101/2021.07.28.454143 — microbiology — Posted on 2021-07-28

440 Phage co-transport with hyphal-riding bacteria fuels bacterial invasion in water-unsaturated microbial ecosystems

You, X.; Kallies, R.; Kühn, I.; Schmidt, M.; Harms, H.; Chatzinotas, A.; Wick, L. Y.

10.1101/2021.07.28.454208 — microbiology — Posted on 2021-07-28

441 Metallothionein 3-zinc axis suppresses caspase-11 inflammasome activation and impairs antibacterial immunity

Chowdhury, D.; Gardner, J.; Satpati, A.; Nookala, S.; Mukundan, S.; Porollo, A.; Landero Figueroa, J.; Subramanian, K.

10.1101/2021.07.28.454033 — immunology — Posted on 2021-07-28

442 PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade

Srour, N.; Villareal, O. D.; Yu, Z.; Preston, S.; Miller, W. H.; Szewczyk, M.; Barsyte-Lovejoy, D.; Xu, H.; del Rincon, S. V.; Richard, S.

10.1101/2021.07.28.454202 — immunology — Posted on 2021-07-28

443 Science in School: Transforming K-12 Outreach through Scientist Teacher Partnerships

Abramowitz, B.; Ennes, M.; Killingsworth, S.; Antonenko, P.; MacFadden, B.; Ivory, A.

10.1101/2021.07.27.453770 — scientific communication and education — Posted on 2021-07-28

444 Unveiling Mutation Effects on the Structural Dynamics of the Main Protease from SARS-CoV-2 with Hybrid Simulation Methods

Philot, E. A.; Gasparini, P.; de Mattos, J. C.; Magro, A.; Torres-Bonfim, E.; Quiroz, R. C. N.; Klioussof, A.; Perahia, D.; Scott, A. L. B.

10.1101/2021.07.17.452787 — biophysics — Posted on 2021-07-28

445 Elevated fear responses to threatening cues in rats with early life stress is associated with greater excitability and loss of gamma oscillations in ventral-medial prefrontal cortex

Bercum, F. M.; Navarro Gomez, M. J.; Saddoris, M. P.

10.1101/2021.07.28.454150 — neuroscience — Posted on 2021-07-28

446 BRET-based self-cleaving biosensors for SARS-CoV-2 3CLpro Inhibitor Discovery

Hou, N.; Peng, C.; Zhang, L.; Zhu, Y.; Hu, Q.

10.1101/2021.07.28.454072 — synthetic biology — Posted on 2021-07-28

447 Rapid redistribution and extensive binding of NANOG and GATA6 at shared regulatory elements underlie specification of divergent cell fates

Thompson, J. J.; Lee, D. J.; Mitra, A.; Frail, S.; Dale, R.; Rocha, P. P.

10.1101/2021.07.28.454132 — developmental biology — Posted on 2021-07-28

448 Unearthing Shifts in Microbial Communities Across a Soil Disturbance Gradient

Seitz, T. J.; Schütte, U. M. E.; Drown, D. M.

10.1101/2021.07.28.454095 — microbiology — Posted on 2021-07-28

449 Increased risk of thrombocytopenia and death in patients with bacteremia caused by high alpha toxin-producing methicillin-resistant Staphylococcus aureus.

Alhurayri, F.; Porter, E.; Douglas-Louis, R.; Minejima, E.; Bubeck Wardenburg, J.; Wong-Beringer, A.

10.1101/2021.07.27.454087 — microbiology — Posted on 2021-07-28

450 SARS-CoV-2 Lambda variant exhibits higher infectivity and immune resistance

Kimura, I.; Kosugi, Y.; Wu, J.; Yamasoba, D.; Butlertanaka, E. P.; Tanaka, Y. L.; Liu, Y.; Shirakawa, K.; Kazuma, Y.; Nomura, R.; Horisawa, Y.; Tokunaga, K.; Takaori-Kondo, A.; Arase, H.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Saito, A.; Nakagawa, S.; Sato, K.

10.1101/2021.07.28.454085 — microbiology — Posted on 2021-07-28

451 The Achilles' heel of coronaviruses: targeting the 5' Polyuridines tract of the antigenome to inhibit Mouse coronavirus virus-induced cell death

Ullah, H.; Averick, S.; Tang, Q.

10.1101/2021.07.26.453908 — microbiology — Posted on 2021-07-28

452 SARS-CoV-2 in the Republic of Guinea: Fragment and Whole-Genome Sequencing, Phylogenetic Analysis

Kritsky, A. A.; Krasnov, Y. M.; Keita, M.; Keita, S.; Fedorov, A. V.; Shevtsova, A. P.; Guseva, N. P.; Kazorina, E. V.; Sosedova, E. A.; Katyshev, A. D.; Naryshkina, E. A.; Kolomoets, E. V.; Shcherbakova, S. A.; Popova, A. Y.; Kutyrev, V. V.

10.1101/2021.07.28.454098 — microbiology — Posted on 2021-07-28

453 Single-Cell Profiling of the Antigen-Specific Response to BNT162b2 SARS-CoV-2 RNA Vaccine

Kramer, K. J.; Wilfong, E. M.; Voss, K.; Barone, S.; Shiakolas, A. R.; Raju, N.; Roe, C. E.; Suryadevara, N.; Walker, L. M.; Wall, S. C.; Paulo, A.; Schaefer, S.; Dahunsi, D.; Westlake, C. S.; Crowe, J. E.; Carnahan, R. H.; Rathmell, J. C.; Bonami, R. H.; Georgiev, I. S.; Irish, J. M.

10.1101/2021.07.28.453981 — immunology — Posted on 2021-07-28

454 Ifenprodil Intracerebrally Offers Neuroprotection against 6-OHDA-Induced Toxicity in SD-Rats via Enhancing Autophagy Function

Zhao, X.; Tian, F.; Guo, C.; Yu, X.

10.1101/2021.07.28.454206 — neuroscience — Posted on 2021-07-28

455 Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8

Langer, L. M.; Bonneau, F.; Gat, Y.; Conti, E.

10.1101/2021.07.28.454180 — biochemistry — Posted on 2021-07-28

456 Evolution of Regulatory Complexity for Cell-Cycle Control

von der Dunk, S. H. A.; Snel, B.; Hogeweg, P.

10.1101/2021.07.28.454145 — evolutionary biology — Posted on 2021-07-28

457 An efficient method of evaluating multiple concurrent management actions on invasive populations

Davis, A. J.; Farrar, R. O.; Jump, B.; Hall, P. T.; Guerrant, T.; Pepin, K.

10.1101/2021.07.28.452079 — ecology — Posted on 2021-07-28

458 Active Cell Divisions Generate Exotic Fourfold Orientationally Ordered Phase in Living Tissue

Cislo, D. J.; Qin, H.; Yang, F.; Bowick, M. J.; Streichan, S. J.

10.1101/2021.07.28.453899 — developmental biology — Posted on 2021-07-28

459 Structural insights into tick-borne encephalitis virus neutralization and animal protection by a therapeutic antibody

Baykov, I. K.; Chojnowski, G.; Pachl, P.; Matveev, A. L.; Moor, N. A.; Emelianova, L. A.; Rezacova, P. M.; Lamzin, V. S.; Tikunova, N. V.

10.1101/2021.07.28.453943 — biochemistry — Posted on 2021-07-28

460 Large-scale genome-wide association study of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits.

May-Wilson, S.; Matoba, N.; Wade, K. H.; Hottenga, J.-J.; Concas, M. P.; Mangino, M.; Grzeszkowiak, E. J.; Menni, C.; Gasparini, P.; Timpson, N. J.; Veldhuizen, M. G.; de Geus, E. J.; Wilson, J. F.; Pirastu, N.

10.1101/2021.07.28.454120 — genetics — Posted on 2021-07-28

461 Filopodia powered by class X myosin promote fusion of mammalian myoblasts

Hammers, D. W.; Hart, C. C.; Matheny, M. K.; Heimsath, E. G.; Lee, Y. i.; Hammer, J. A.; Cheney, R. E.; Sweeney, L.

10.1101/2021.07.28.454163 — cell biology — Posted on 2021-07-28

462 Host cell maturation modulates parasite invasion and sexual differentiation in Plasmodium.

Hentzschel, F.; Gibbins, M. P.; Attipa, C.; Beraldi, D.; Moxon, C.; Otto, T. D.; Marti, M.

10.1101/2021.07.28.453984 — microbiology — Posted on 2021-07-28

463 T helper cell-licensed mast cells promote inflammatory Th17 cells

Leveque, E.; Joulia, R.; Petitfils, C.; Mas-Orea, X.; Payros, G.; Laurent, C.; Gaudenzio, N.; Dietrich, G.; Valitutti, S.; Cenac, N.; Espinosa, E.

10.1101/2021.07.28.454103 — immunology — Posted on 2021-07-28

464 miR-17~92 exerts stage-specific effects in adult V-SVZ neural stem cell lineages

Favaloro, F.; DeLeo, A.; Delgado, A.; Doetsch, F.

10.1101/2021.07.28.454109 — neuroscience — Posted on 2021-07-28

465 Upregulation of breathing rate during running exercise by central locomotor circuits

Herent, C.; Diem, S.; Fortin, G.; Bouvier, J.

10.1101/2021.07.28.453983 — neuroscience — Posted on 2021-07-28

466 Realism Matters. Eye movements in VR reveal prior tool knowledge, intended interaction, and end-state comfort planning

Keshava, A.; Gottschewsky, N.; Balle, S.; Nezami, F. N.; Schueler, T.; Koenig, P.

10.1101/2021.07.27.454022 — neuroscience — Posted on 2021-07-28

467 Integrative analysis of the salt stress response in cyanobacteria

Klaehn, S.; Mikkat, S.; Riediger, M.; Georg, J.; Hess, W. R.; Hagemann, M.

10.1101/2021.07.28.454097 — systems biology — Posted on 2021-07-28

468 Nuclear-cytoplasmic compartmentalization promotes robust timing of mitotic events by cyclin B1-Cdk1

Maryu, G.; Yang, Q.

10.1101/2021.07.28.454130 — systems biology — Posted on 2021-07-28

469 Water Nanoconfined in a Hydrophobic Pore: MD Simulations and Water Models

Lynch, C.; Klesse, G.; Rao, S.; Tucker, S. J.; Sansom, M.

10.1101/2021.07.28.453939 — biophysics — Posted on 2021-07-28

470 The contribution of uncharted RNA sequences to tumor identity in lung adenocarcinoma

Wang, Y.; Xue, H.; Aglave, M.; Laine, A.; Gallopin, M.; Gautheret, D.

10.1101/2021.07.28.454105 — bioinformatics — Posted on 2021-07-28

471 Unravelling the effects of disease-associated mutations in TDP-43 protein via molecular dynamics simulation and machine learning

Sharma, A.; Dey, P.

10.1101/2021.07.28.454112 — bioinformatics — Posted on 2021-07-28

472 Solution NMR and racemic crystallography provide insights into a novel structural class of cyclic plant peptides

Payne, C. D.; Vadlamani, G.; Hajiaghaalipour, F.; Muhammad, T.; Fisher, M. F.; Andersson, H. S.; Göransson, U.; Clark, R. J.; Bond, C. S.; Mylne, J. S.; Rosengren, K. J.

10.1101/2021.07.28.454061 — biochemistry — Posted on 2021-07-28

473 A non-functional copy of the salmonid sex determining gene (sdY) is responsible for the "apparent" XY females in Chinook salmon, Oncorhynchus tshawytscha.

Bertho, S.; Herpin, A.; Jouanno, E.; Yano, A.; Bobe, J.; Parrinello, H.; Journot, L.; Guyomard, R.; Thomas, M.; Swanson, P.; McKinney, G. J.; Kevin, W.; Mariah, M.; Schartl, M.; Guiguen, Y.

10.1101/2021.07.28.454148 — genetics — Posted on 2021-07-28

474 The transcriptional corepressor CTBP-1 acts with the SOX family transcription factor EGL-13 to maintain AIA interneuron cell identity in C. elegans

Saul, J.; Hirose, T.; Horvitz, R.

10.1101/2021.07.28.454018 — developmental biology — Posted on 2021-07-28

475 Inhibition of Mul1-mediated ubiquitination promotes mitochondria-associated translation

Gao, Y.; Cardamone, M. D.; Kwan, J.; Hekman, R.; Orofino, J.; Lyons, S. M.; Emili, A.; Perissi, V.

10.1101/2021.07.28.454107 — cell biology — Posted on 2021-07-28

476 Variability in an effector gene promoter of a necrotrophic fungal pathogen dictates epistasis and effector-triggered susceptibility in wheat

John, E.; Jacques, S.; Phan, H.; Liu, L.; Pereira, D.; Croll, D.; Singh, K.; Oliver, R. P.; Tan, K.-C.

10.1101/2021.07.28.454099 — microbiology — Posted on 2021-07-28

477 Automated slice-specific z-shimming for fMRI of the human spinal cord

Kaptan, M.; Vannesjo, S. J.; Mildner, T.; Horn, U.; Hartley-Davies, R.; Oliva, V.; Brooks, J. C. W.; Weiskopf, N.; Finsterbusch, J.; Eippert, F.

10.1101/2021.07.27.454049 — neuroscience — Posted on 2021-07-28

478 Data and model considerations for estimating time-varying functional connectivity in fMRI

Ahrends, C.; Stevner, A.; Pervaiz, U.; Kringelbach, M. L.; Vuust, P.; Woolrich, M.; Vidaurre, D.

10.1101/2021.07.28.454017 — neuroscience — Posted on 2021-07-28

479 Symmetry and simplicity spontaneously emerge from the algorithmic nature of evolution

Johnston, I.; Dingle, K.; Greenbury, S. F.; Camargo, C. Q.; Doye, J. P. K.; Ahnert, S. E.; louis, a.

10.1101/2021.07.28.454038 — evolutionary biology — Posted on 2021-07-28

480 m6A is required for resolving progenitor identity during planarian stem cell differentiation

Dagan, Y.; Yesharim, Y.; Bonneau, A. R.; Schwartz, S.; Reddien, P. W.; Wurtzel, O.

10.1101/2021.07.27.453979 — developmental biology — Posted on 2021-07-28

481 Gds1 interacts with NuA4 to promote H4 acetylation at ribosomal protein genes

Joo, Y. J.; Buratowski, S.

10.1101/2021.07.27.454094 — molecular biology — Posted on 2021-07-28

482 CRISPR-Cas Controls Cryptic Prophages

Song, S.; Wood, T. K.

10.1101/2021.07.28.454074 — molecular biology — Posted on 2021-07-28

483 Characterization of a Novel Plasmid in Serratia marcescens Harboring blaGES-5 Isolated from a Nosocomial Outbreak in Japan

Nakanishi, N.; Komatsu, S.; Iwamoto, T.; Nomoto, R.

10.1101/2021.07.27.454091 — microbiology — Posted on 2021-07-28

484 DectiSomes: Glycan Targeting of Liposomal Drugs Improves the Treatment of Disseminated Candidiasis

Ambati, S.; Pham, T.; Lewis, Z. A.; Lin, X.; Meagher, R. B.

10.1101/2021.07.27.454088 — microbiology — Posted on 2021-07-28

485 Structural and functional network-level reorganization in the coding of auditory motion directions and sound source locations in the absence of vision

Battal, C.; Gurtubay-Antolin, A.; Rezk, M.; Mattioni, S.; Bertonati, G.; Occelli, V.; Bottini, R.; Targher, S.; Maffei, C.; Jovicich, J.; Collignon, O.

10.1101/2021.07.28.454106 — neuroscience — Posted on 2021-07-28

486 Navigating a diversity of turbulent plumes is enhanced by sensing complementary temporal features of odor signals

Jayaram, V.; Kadakia, N.; Emonet, T.

10.1101/2021.07.28.454116 — neuroscience — Posted on 2021-07-28

487 Information silos distort biomedical research

Rodriguez-Esteban, R.

10.1101/2021.07.26.453749 — scientific communication and education — Posted on 2021-07-28

488 Phosphate starvation response precedes drought response in field-grown plants

Nagatoshi, Y.; Ikazaki, K.; Mizuno, N.; Kobayashi, Y.; Fujii, K.; Ogiso-Tanaka, E.; Ishimoto, M.; Yasui, Y.; Oya, T.; Fujita, Y.

10.1101/2021.07.28.453724 — plant biology — Posted on 2021-07-28

489 B Cell Receptor Signaling Drives APOBEC3 Expression Via Direct Enhancer Regulation in Chronic Lymphocytic Leukemia B Cells

Wang, Z.; Yan, H.; Boysen, J. C.; Secreto, C. R.; Zhong, J.; Zhou, J.; Gan, H.; Yu, C.; Braggio, E.; Slager, S. L.; Parikh, S. A.; Kay, N. E.

10.1101/2021.07.27.454050 — cancer biology — Posted on 2021-07-28

490 Short-term stimulation of collective cell migration in tissues reprograms long-term supracellular dynamics

Wolf, A. E.; Heinrich, M. A.; Breinyn, I. B.; Zajdel, T. J.; Cohen, D. J.

10.1101/2021.07.27.453602 — biophysics — Posted on 2021-07-28

491 The iron maiden. Cytosolic aconitase/IRP1 conformational transition in the regulation of ferritin translation and iron hemostasis

Hognon, C.; Bignon, E.; Harle, G.; Touche, N.; Grandemange, S.; Monari, A.

10.1101/2021.07.28.454104 — biophysics — Posted on 2021-07-28

492 Heritable changes in division speed accompany the diversification of single T cell fate

Plambeck, M.; Kazeroonian, A.; Loeffler, D.; Schroeder, T.; Busch, D. H.; Flossdorf, M.; Buchholz, V. R.

10.1101/2021.07.28.454102 — immunology — Posted on 2021-07-28

493 The determinants of African Swine Fever Virus Virulence - the Georgia 2007/1 strain and the host macrophage response

Cackett, G.; Portugal, R.; Matelska, D.; Dixon, L.; Werner, F.

10.1101/2021.07.26.453801 — microbiology — Posted on 2021-07-28

494 Utilization efficiency of human milk oligosaccharides by human-associated Akkermansia is strain-dependent

Luna, E.; Parkar, S. G.; Kirmiz, N.; Hartel, S.; Hearn, E.; Hossine, M.; Kurdian, A.; Mendoza, C.; Orr, K.; Padilla, L.; Ramirez, K.; Salcedo, P.; Serrano, E.; Choudhury, B.; Paulchakrabarti, M.; Parker, C. T.; Huynh, S.; Cooper, K.; Flores, G. E.

10.1101/2021.07.26.453919 — microbiology — Posted on 2021-07-28

495 Annual dynamics of Zymoseptoria tritici populations in wheat cultivar mixtures: a compromise between the efficiency and durability of a recently broken-down resistance gene?

Orellana-Torrejon, C.; Vidal, T.; Boixel, A.-L.; Gelisse, S.; Saint-Jean, S.; Frederic, S.

10.1101/2021.04.23.441180 — microbiology — Posted on 2021-07-28

496 Maturation, developmental site, and pathology dictate murine neutrophil function

Mackey, J. B. G.; McFarlane, A. J.; Jamieson, T.; Jackstadt, R.; Raffo-Iraolagoitia, X. L.; Secklehner, J.; Cortes-Lavaud, X.; Fercoq, F.; Clarke, W.; Hedley, A.; Gilroy, K.; Lilla, S.; Vuononvirta, J.; Graham, G. J.; De Filippo, K.; Murphy, D. J.; Steele, C. W.; Norman, J. C.; Bird, T. G.; Mann, D. A.; Morton, J. P.; Zanivan, S.; Sansom, O. J.; Carlin, L. M.

10.1101/2021.07.21.453108 — immunology — Posted on 2021-07-28

497 Homeostatic scaling is driven by a translation-dependent degradation axis that recruits miRISC remodelling

Srinivasan, B.; Samaddar, S.; Mylavarapu, S. V. S.; Clement, J. P.; Banerjee, S.

10.1101/2020.04.01.020164 — neuroscience — Posted on 2021-07-28

498 DNA METHYLTRANSFERASE 3 (MET3) is regulated by Polycomb Group complex during Arabidopsis endosperm development

Tirot, L.; jullien, p. E.

10.1101/2021.06.28.450243 — plant biology — Posted on 2021-07-28

499 Sex change in aquarium systems establishes the New Zealand spotty wrasse (Notolabrus celidotus) as a temperate model species for the investigation of sequential hermaphroditism

Goikoetxea, A.; Muncaster, S.; Todd, E. V.; Lokman, P. M.; Robertson, H.; Moraes, C.; Damsteegt, E. L.; Gemmell, N. J.

10.1101/2020.08.28.271973 — physiology — Posted on 2021-07-28

500 Taxonomic bias in AMP prediction of invertebrate peptides

Radai, Z.; Kiss, J.; Nagy, N.

10.1101/2021.03.04.433925 — bioinformatics — Posted on 2021-07-28

501 Can AlphaFold2 predict protein-peptide complex structures accurately?

Ko, J.; Lee, J.

10.1101/2021.07.27.453972 — bioinformatics — Posted on 2021-07-28

502 A phospho-switch at Acinus-Serine437 controls autophagic responses to cadmium exposure and neurodegenerative stress

Nandi, N.; Zaidi, Z.; Tracy, C.; Krämer, H.

10.1101/2021.07.27.453988 — cell biology — Posted on 2021-07-28

503 ESCRT-I controls lysosomal membrane protein homeostasis and restricts MCOLN1-dependent TFEB/TFE3 signaling.

Wrobel, M.; Szymanska, E.; Budick-Harmelin, N.; Kolmus, K.; Goryca, K.; Dabrowska, M.; Paziewska, A.; Mikula, M.; Cendrowski, J.; Miaczynska, M.

10.1101/2021.07.26.453823 — cell biology — Posted on 2021-07-28

504 Metabolomics and microbiome reveal impacts of rhizosphere metabolites on alfalfa continuous cropping

Wang, R.; Liu, J.; Jiang, W.; Ji, P.; Li, Y.

10.1101/2021.07.25.453728 — microbiology — Posted on 2021-07-28

505 Staphylococci planktonic and biofilm environments differentially affect macrophage immune activation and osteoclastogenic differentiation.

Seebach, E.; Elschner, T.; Kraus, F. V.; Souto-Carneiro, M.; Kubatzky, K.

10.1101/2021.07.26.453923 — immunology — Posted on 2021-07-28

506 MAFB surrogates the glucocorticoid receptor ability to induce tolerogenesis in dendritic cells

Morante-Palacios, O.; Ciudad, L.; Micheroli, R.; de la Calle-Fabregat, C.; Li, T.; Barbisan, G.; Houtman, M.; Edalat, S.; Frank-Bertoncelj, M.; Ospelt, C.; Ballestar, E.

10.1101/2021.07.27.453975 — immunology — Posted on 2021-07-28

507 Endorsement and Phylogenetic Analysis of some Fabaceae Plants based on DNA Barcoding gene MatK

Abdelsalam, N. R.; Hasan, M. E.; Rabie, S. M. A.; El-wakeel, H. E.-D. M. F.; Zaitoun, A. F.; Ghareeb, R. Y.; Abdelsalam, A. Z.; Aly, H. M.; Ibrahim, A. A.; Hemeida, A. A.

10.1101/2021.07.27.454001 — bioinformatics — Posted on 2021-07-28

508 Application of Modular Response Analysis to Medium- to Large-Size Biological Systems

Mekedem, M.; Ravel, P.; Colinge, J.

10.1101/2021.07.27.453942 — systems biology — Posted on 2021-07-27

509 Effects of co-incubation of LPS-stimulated RAW 264.7 macrophages on leptin production by 3T3-L1 adipocytes: A method for co-incubating distinct adipose tissue cell lines.

Caldari-Torres, C.; Beck, J.

10.1101/2021.07.27.454005 — cell biology — Posted on 2021-07-27

510 Transcriptome-wide in vivo mapping of cleavage sites for the compact cyanobacterial ribonuclease E reveals insights into its function and substrate recognition

Hoffmann, U. A.; Heyl, F.; Rogh, S. N.; Wallner, T.; Backofen, R.; Hess, W. R.; Steglich, C.; Wilde, A.

10.1101/2021.07.27.453982 — microbiology — Posted on 2021-07-27

511 Effects of a blend of chestnut and quebracho tannins on gut health and performance of broiler chickens

Redondo, E. A.; Redondo, L. M.; Bruzzone, O. A.; Diaz-Carrasco, J. M.; Cabral, C.; Garces, V. M.; Lineiro, M. M.; Fernandez Miyakawa, M. E.

10.1101/2021.07.27.454004 — microbiology — Posted on 2021-07-27

512 Selection and evaluation of qPCR reference genes for expression analysis in the tiny egg parasitoid wasp, Trichogramma dendrolimi Matsumura (Hymenoptera: Trichogrammatidae)

Huo, L.-x.; Bai, X.-p.; Che, W.-N.; Ning, S.-f.; Lv, L.; Zhang, L.-s.; Zhou, J.-c.; Dong, H.

10.1101/2021.07.27.454008 — zoology — Posted on 2021-07-27

513 BFG-PCA: tools and resources that expand the potential for binary protein interaction discovery

Evans-Yamamoto, D.; Rouleau, F. D.; Nanda, P.; Makanae, K.; Liu, Y.; Despres, P. C.; Matsuo, H.; Seki, M.; Dube, A. K.; Ascencio, D.; Yachie, N.; Landry, C. R.

10.1101/2021.07.27.453987 — systems biology — Posted on 2021-07-27

514 Executable Network of SARS-CoV-2-Host Interaction Predicts Drug Combination Treatments

Howell, R.; Clarke, M. A.; Reuschl, A.-K.; Chen, T.; Abott-Imboden, S.; Singer, M.; Lowe, D. M.; Bennett, C. L.; Chain, B.; Jolly, C.; Fisher, J.

10.1101/2021.07.27.453973 — systems biology — Posted on 2021-07-27

515 Antifungal activity of Conocephalum conicum(L) Dumort. (Marchantiophyta) against Fusarium oxysporum f. sp. lycopersici

Negi, K.; Chaturvedi, P.

10.1101/2021.07.27.454003 — plant biology — Posted on 2021-07-27

516 The genetic interaction of REVOLUTA and WRKY53 links plant development, senescence, and immune responses

Bresson, J.; Doll, J.; Vasseur, F.; Stahl, M.; von Roepenack-Lahaye, E.; Kilian, J.; Stadelhofer, B.; Kremer, J. M.; Kolb, D.; Wenkel, S.; Zentgraf, U.

10.1101/2021.07.27.454007 — plant biology — Posted on 2021-07-27

517 Average stride length and stride rate of Thoroughbreds and Quarter Horses during 'Sprint and 'Classic races

Vergara-Hernandez, F. B.; Nielsen, B. D.; Robison, C. I.; Fabus, T. A.; Kompare, J. L.; LeCompte Lazic, R. A.; Colbath, A. C.

10.1101/2021.07.27.453998 — physiology — Posted on 2021-07-27

518 Parallel Implementation of Smith-Waterman Algorithm on FPGA

Oliveira, F. O. F. d.; Dias, L. A.; Fernandes, M.

10.1101/2021.07.27.454006 — bioinformatics — Posted on 2021-07-27

519 Can AlphaFold2 predict protein-peptide complex structures accurately?

Ko, J.; Lee, J.

10.1101/2021.07.27.453972 — bioinformatics — Posted on 2021-07-27

520 Complete Mitochondrial and Plastid DNA Sequences of the Freshwater Green Microalga Medakamo hakoo

Takusagawa, M.; Kato, S.; Matsunaga, S.; Maruyama, S.; Tsujimoto-Inui, Y.; Nozaki, H.; Yagisawa, F.; Ohnuma, M.; Kuroiwa, H.; Kuroiwa, T.; Misumi, O.

10.1101/2021.07.27.453968 — genomics — Posted on 2021-07-27

521 Can fMRI functional connectivity index dynamic neural communication?

Alonso Martinez, S.; Llera Arenas, A.; Ter Horst, G. T.; Vidaurre, D.

10.1101/2021.07.27.453965 — neuroscience — Posted on 2021-07-27

522 Orthogonal but linked neural codes for value

Maisson, D. J.; Fine, J. M.; Yoo, S. B. M.; Cash-Padgett, T. D.; Wang, M. Z.; Sleezer, B. J.; Zimmermann, J.; Hayden, B. Y.

10.1101/2021.07.27.453966 — neuroscience — Posted on 2021-07-27

523 Measuring the temporal quality of a biodiversity database

Underhill, L.

10.1101/2021.07.27.453997 — zoology — Posted on 2021-07-27

524 Perinatal maternal chronic exposure to dibutyl phthalate promotes visceral obesity in adult female offspring

Zhou, K.; Cheng, R.; Yang, M.; Shen, X.; Luo, X.; Ma, L.; Xu, L.; Zhang, J.

10.1101/2021.07.27.454002 — pharmacology and toxicology — Posted on 2021-07-27

525 1,25(OH)2D3 attenuates hepatic insulin resistance in rats with streptozotocin -induced diabetes via antioxidation

Huang, G.; Ding, R.; Zhang, Y.; Gao, J.; Li, W.; Li, X.

10.1101/2021.07.27.453999 — pharmacology and toxicology — Posted on 2021-07-27

526 Molecular Pathophysiology of Cardiac Injury and Cardiac Microthrombi in Fatal COVID-19: Insights from Clinico-histopathologic and Single Nuclei RNA Sequencing Analyses

Fukuma, N.; Hulke, M. L.; Brener, M. I.; Golob, S.; Zilinyi, R.; Zhou, Z.; Tzimas, C.; Russo, I.; McGroder, C.; Pfeiffer, R.; Chong, A.; Zhang, G.; Burkhoff, D.; Leon, M. B.; Maurer, M.; Moses, J. W.; Uhlemann, A.-C.; Hibshoosh, H.; Uriel, N.; Szabolcs, M. J.; Redfors, B.; Marboe, C. C.; Baldwin, M. R.; Tucker, N. R.; Tsai, E. J.

10.1101/2021.07.27.453843 — pathology — Posted on 2021-07-27

527 Met-HER3 crosstalk supports proliferation via MPZL3 in MET-amplified cancer cells

Stern, Y. E.; Duhamel, S.; Al-Ghabkari, A.; Monast, A.; Fiset, B.; Aboulizadeh, F.; Yao, Z.; Stagljar, I.; Walsh, L. A.; Park, M.

10.1101/2021.07.27.454013 — cancer biology — Posted on 2021-07-27

528 Resurrecting Golgi proteins to grasp Golgi ribbon formation and self-association under stress

mendes, l. f. s.; Batista, M. R. B.; Kava, E.; Bleicher, L.; Micheletto, M. C.; Costa-Filho, A. J.

10.1101/2021.07.27.453980 — biophysics — Posted on 2021-07-27

529 Accelerated epigenetic aging and inflammatory/immunological profile (ipAGE) in patients with chronic kidney disease

Yusipov, I.; Kondakova, E.; Kalyakulina, A.; Krivonosov, M.; Lobanova, N.; Bacalini, M. G.; Franceschi, C.; Vedunova, M.; Ivanchenko, M.

10.1101/2021.07.23.453588 — bioinformatics — Posted on 2021-07-27

530 Quantification and visualization of the tumor microenvironment heterogeneity from spatial transcriptomic experiments

Ospina, O. E.; Wilson, C. M.; Soupir, A. C.; Berglund, A.; Smalley, I.; Tsai, K. Y.; Fridley, B. L.

10.1101/2021.07.27.454023 — bioinformatics — Posted on 2021-07-27

531 A Novel, Improved, Application for the Normalization of RNA-seq Based Expression Data in Complex Polyploids.

Lloyd Evans, D.

10.1101/2021.07.27.453947 — bioinformatics — Posted on 2021-07-27

532 Deep learning-based segmentation of high-resolution computed tomography image data outperforms commonly used automatic bone segmentation methods

Patton, D. M.; Henning, E. N.; Goulet, R. W.; Carroll, S. K.; Bigelow, E. M. R.; Provencher, B.; Piche, N.; Marsh, M.; Jepsen, K. J.; Bredbenner, T. L.

10.1101/2021.07.27.453890 — bioengineering — Posted on 2021-07-27

533 Targeted Protein Acetylation in Cells Using Heterobifunctional Molecules

Wang, W. W.; Chen, L.-Y.; Wozniak, J.; Jadhav, A. M.; Anderson, H.; Malone, T.; Parker, C. G.

10.1101/2021.07.27.454011 — biochemistry — Posted on 2021-07-27

534 Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism

Ryan, D. G.; Yang, M.; Prag, H. A.; Blanco, G. R.; Nikitopoulou, E.; Segarra-Mondejar, M.; Powell, C. A.; Young, T.; Burger, N.; Miljkovic, J. L.; Minczuk, M.; Murphy, M. P.; Von Kriegsheim, A.; Frezza, C.

10.1101/2021.07.27.453996 — biochemistry — Posted on 2021-07-27

535 Substitution Rate Variation in a Robust Procellariiform Seabird Phylogeny is not Solely Explained by Body Mass, Flight Efficiency, Population Size or Life History Traits

Estandia, A.; Chesser, R. T.; James, H. F.; Levy, M. A.; Ferrer Obiol, J.; Bretagnolle, V.; Gonzalez-Solis, J.; Welch, A. J.

10.1101/2021.07.27.453752 — evolutionary biology — Posted on 2021-07-27

536 Host-symbiont stress response to lack-of-sulfide in the giant ciliate mutualism

Espada-Hinojosa, S.; Drexel, J.; Kesting, J.; Kniha, E.; Pifeas, I.; Schuster, L.; Volland, J.-M.; Zambalos, H. C.; Bright, M.

10.1101/2021.07.27.454000 — ecology — Posted on 2021-07-27

537 ANTH domains within CALM, HIP1R, and Sla2 recognize ubiquitin internalization signals.

Pashkova, N.; Gakhar, L.; Winistorfer, S.; Minard, A. Y.; Schnicker, N. J.; Yu, L.; Johnson, I. E.; Piper, R. C.

10.1101/2021.07.27.454047 — cell biology — Posted on 2021-07-27

538 Site-specific recognition of SARS-CoV-2 nsp1 protein with a tailored titanium dioxide nanoparticle

Agback, P.; Agback, T.; Dominguez, F.; Frolova, E. I.; Seisenbaeva, G.; Kessler, V.

10.1101/2021.07.27.453834 — molecular biology — Posted on 2021-07-27

539 Emotional states as distinct configurations of functional brain networks

Dan, R.; Weinstock, M.; Goelman, G.

10.1101/2021.07.23.453552 — neuroscience — Posted on 2021-07-27

540 Sex differences in age- and episodic memory-related effects on task-based functional connectivity

Subramaniapillai, S.; Rajagopal, S.; Ankudowich, E.; Pasvanis, S.; Misic, B.; Rajah, N.

10.1101/2021.07.27.453878 — neuroscience — Posted on 2021-07-27

541 Surveillance of airborne plant disease dissemination at continental scale using air mass trajectory analysis and network theory

Radici, A.; Martinetti, D.; Bevacqua, D.

10.1101/2021.06.04.447025 — plant biology — Posted on 2021-07-27

542 Non-invasive imaging of gene expression and protein secretion dynamics in living mice

Nourse, J.; Tokalov, S.; Khokhar, S.; Khan, E.; Schott, L. K.; Hinz, L.; Eder, L.; Arnold-Schild, D.; Probst, H. C.; Danckwardt, S.

10.1101/2021.07.08.451623 — pharmacology and toxicology — Posted on 2021-07-27

543 Anti-arthralgic activity of the n-hexane extract (HTp) of yellow oleander seeds;Thevetia peruviana (Pers.) K. Schum

Odimegwu, J. I.; Olabisi, F. O.

10.1101/2021.07.27.453963 — pharmacology and toxicology — Posted on 2021-07-27

544 Deposition chamber technology as building blocks for a standardized brain-on-chip framework

Maisonneuve, B. G. C.; Libralesso, L.; Miny, L.; Batut, A.; Rontard, J.; Gleyzes, M.; Boudra, B.; Vieira, J.; Debis, D.; Larramendy, F.; Jost, V.; Honegger, T.

10.1101/2021.06.21.449231 — bioengineering — Posted on 2021-07-27

545 Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans

Perez-Borrajero, C.; Podvalnaya, N.; Holleis, K.; Raffael, L.; Karaulanov, E.; Simon, B.; Basquin, J.; Hennig, J.; Ketting, R. F.; Falk, S.

10.1101/2021.05.20.444926 — biochemistry — Posted on 2021-07-27

546 Evolutionary rescue in one dimensional stepping stone models

Tomasini, M.; Peischl, S.

10.1101/2020.10.29.360842 — evolutionary biology — Posted on 2021-07-27

547 Phylogenetic distribution and expression pattern analyses identified a divergent basal body assembly protein involved in land plant spermatogenesis

Koshimizu, S.; Minamino, N.; Nishiyama, T.; Yoro, E.; Ebine, K.; Sakakibara, K.; Ueda, T.; Yano, K.

10.1101/2021.07.25.453666 — evolutionary biology — Posted on 2021-07-27

548 Exclusion of the fittest predicts microbial community diversity in fluctuating environments

Shibasaki, S.; Mobilia, M.; Mitri, S.

10.1101/2020.07.22.216010 — ecology — Posted on 2021-07-27

549 Paracrine regulation of neural crest EMT by placodal MMP28

GOUIGNARD, N.; BIBONNE, A.; Mata, J. F.; Bajanca, F.; Berki, B.; Barriga, E. H.; SAINT-JEANNET, J.-P.; THEVENEAU, E.

10.1101/2020.11.19.389544 — developmental biology — Posted on 2021-07-27

550 Counting actin in contractile rings reveals novel contributions of cofilin and type II myosins to fission yeast cytokinesis

Malla, M.; Pollard, T. D.; Chen, Q.

10.1101/2021.07.26.453848 — cell biology — Posted on 2021-07-27

551 A Tad-like apparatus is required for contact-dependent prey killing in predatory social bacteria

Seef, S.; Herrou, J.; de Boissier, P.; My, L.; Brasseur, G.; Robert, D.; Jain, R.; Mercier, R.; Cascales, E.; Habermann, B. H.; Mignot, T.

10.1101/2021.02.25.432843 — microbiology — Posted on 2021-07-27

552 Chemoreceptor Co-Expression in Drosophila Olfactory Neurons

Task, D.; Lin, C.-C.; Vulpe, A.; Afify, A.; Ballou, S.; Brbic, M.; Schlegel, P.; Jefferis, G. S. X. E.; Li, H.; Menuz, K.; Potter, C. J.

10.1101/2020.11.07.355651 — neuroscience — Posted on 2021-07-27

553 Alzheimer's Disease Classification Accuracy is Improved by MRI Harmonization based on Attention-Guided Generative Adversarial Networks

Sinha, S.; Thomopoulos, S. I.; Lam, P.; Muir, A.; Thompson, P. M.

10.1101/2021.07.26.453862 — neuroscience — Posted on 2021-07-27

554 Distinct molecular pathways govern presynaptic homeostatic plasticity

Nair, A. G.; Muttathukunnel, P.; Müller, M.

10.1101/2020.12.21.423841 — neuroscience — Posted on 2021-07-27

555 Cancer phylogenetics using single-cell RNA-seq data

Moravec, J. C.; Lanfear, R.; Spector, D.; Diermeier, S.; Gavryushkin, A.

10.1101/2021.01.07.425804 — cancer biology — Posted on 2021-07-27

556 Nonlinear post-selection inference for genome-wide association studies

Slim, L.; Azencott, C.-A.; Chatelain, C.

10.1101/2020.09.30.320515 — bioinformatics — Posted on 2021-07-27

557 DeepLIIF: Deep Learning-Inferred Multiplex ImmunoFluorescence for IHC Image Quantification

Ghahremani, P.; Li, Y.; Kaufman, A.; Vanguri, R.; Greenwald, N.; Angelo, M.; Hollmann, T. J.; Nadeem, S.

10.1101/2021.05.01.442219 — bioinformatics — Posted on 2021-07-27

558 Miniaturizing wet scrubbers for aerosolized droplet capture

Lee, U. N.; van Neel, T. L.; Lim, F. Y.; Khor, J. W.; He, J.; Vaddi, R. S.; Ong, A. Q.; Tang, A.; Berthier, J.; Meschke, J. S.; Novosselov, I. V.; Theberge, A. B.; Berthier, E.

10.1101/2021.03.23.436614 — bioengineering — Posted on 2021-07-27

559 Relative brain size and cognitive equivalence in fishes

Triki, Z.; Aellen, M.; Van Schaik, C.; Bshary, R.

10.1101/2021.02.09.430417 — animal behavior and cognition — Posted on 2021-07-27

560 Human genetic analyses of organelles highlight the nucleus in age-related trait heritability

Gupta, R.; Karczewski, K. J.; Howrigan, D.; Neale, B. M.; Mootha, V. K.

10.1101/2021.01.22.427431 — genomics — Posted on 2021-07-27

561 Evolutionary dynamics of neutral phenotypes under DNA substitution models

Zabad, S.; Moses, A. M.

10.1101/2020.10.26.355438 — evolutionary biology — Posted on 2021-07-27

562 Causal relationship between the right auditory cortex and speech-evoked envelope-following response: Evidence from combined tDCS and EEG

Mai, G.; Howell, P.

10.1101/2020.03.10.985564 — neuroscience — Posted on 2021-07-27

563 Lytic transglycosylases mitigate periplasmic crowding by degrading soluble cell wall turnover products

Weaver, A. I.; Alvarez, L.; Rosch, K. M.; Ahmed, A.; Wang, G. S.; VanNieuwenzhe, M. S.; Cava, F.; Doerr, T.

10.1101/2021.07.27.453986 — microbiology — Posted on 2021-07-27

564 Isolating the Sources of Pipeline-Variability in Group-Level Task-fMRI results

Bowring, A.; Nichols, T.; Maumet, C.

10.1101/2021.07.27.453994 — neuroscience — Posted on 2021-07-27

565 Structural basis of Ty3 retrotransposon integration at RNA Polymerase III-transcribed genes

Abascal-Palacios, G.; Jochem, L.; Pla-Prats, C.; Beuron, F.; Vannini, A.

10.1101/2021.07.27.453949 — biophysics — Posted on 2021-07-27

566 A locus conferring tolerance to Theileria infection in African cattle

Wragg, D.; Cook, E. A. J.; Latre de Late, P.; Sitt, T.; Hemmink, J. D.; Makau, J.; Njeru, R.; Powell, J.; Paxton, E.; Callaby, R.; Talenti, A.; Miyunga, A. A.; Ndambuki, G.; Mwaura, S.; Auty, H.; Matika, O.; Hassan, M. A.; Marshall, K.; Connelley, T. K.; Morrison, L.; Bronsvoort, B. M.; Morrison, W. I.; Toye, P.; Prendergast, J. G.

10.1101/2021.07.26.453771 — genetics — Posted on 2021-07-27

567 Allele-specific analysis reveals exon- and cell-type-specific regulatory effects of Alzheimer's disease-associated genetic variants

He, L.; Loika, Y.; Kulminski, A.

10.1101/2021.07.26.453897 — genetics — Posted on 2021-07-27

568 Modelling porcine reproductive and respiratory syndrome virus dynamics to quantify the contribution of multiple modes of transmission: between-farm animal and vehicle movements, farm-to-farm proximity, feed ingredients, and re-break

Galvis, J. A.; Corzo, C.; Machado, G.

10.1101/2021.07.26.453902 — ecology — Posted on 2021-07-27

569 Phytoplankton exudates provide full nutrition to a subset of accompanying heterotrophic bacteria via carbon, nitrogen and phosphorus allocation

Eigemann, F.; Rahav, E.; Grossart, H.-P.; Aharonovich, D.; Sher, D.; Vogts, A.; Voss, M.

10.1101/2021.07.27.453958 — ecology — Posted on 2021-07-27

570 Proximity labeling identifies LOTUS domain proteins that promote the formation of perinuclear germ granules in C. elegans

Tang, W.; Price, I. F.; Hertz, H. L.; Pastore, B.; Wagner, J.

10.1101/2021.07.27.453989 — cell biology — Posted on 2021-07-27

571 Gliding motility of a uranium tolerant Bacteroidetes bacterium Chryseobacterium sp. strain PMSZPI: Insights into the architecture of spreading colonies

Khare, D.; Chandwadkar, P.; Acharya, C.

10.1101/2021.07.27.453926 — microbiology — Posted on 2021-07-27

572 Electrophysiological measures of visual suppression

Baker, D. H.; Vilidaite, G.; Wade, A. R.

10.1101/2021.07.27.453123 — neuroscience — Posted on 2021-07-27

573 One year later: longitudinal effects of flexible school start times on teenage sleep and subjective psychological outcomes

Biller, A. M.; Molenda, C.; Zerbini, G.; Roenneberg, T.; Winnebeck, E. C.

10.1101/2021.07.27.453940 — neuroscience — Posted on 2021-07-27

574 Optogenetic actuator/biosensor circuits for large-scale interrogation of ERK dynamics identify sources of MAPK signaling robustness.

Dessauges, C.; Mikelson, J.; Dobrzynski, M.; Jacques, M.-A.; Frismantiene, A.; Gagliardi, P. A.; Khammash, M.; Pertz, O.

10.1101/2021.07.27.453955 — systems biology — Posted on 2021-07-27

575 Functional and comparative genomics reveals conserved noncoding sequences in the nitrogen-fixing clade

Pereira, W. J.; Knaack, S. A.; Conde, D.; Chakraborty, S.; Folk, R. A.; Triozzi, P. M.; Balmant, K. M.; Dervinis, C.; Schmidt, H. W.; Ane, J.-M.; Roy, S.; Kirst, M.

10.1101/2021.07.27.453985 — plant biology — Posted on 2021-07-27

576 Ribosomal protein L23 drives the metastasis of hepatocellular carcinoma via upregulating MMP9

Chen, J.; Li, F.; Yang, M.; Zhou, Y.; Deng, H.; Zhou, H.; Cheng, S.; Zhang, D.; He, X.; Mai, L.; Chen, Y.

10.1101/2021.07.27.453993 — cancer biology — Posted on 2021-07-27

577 Analysis of long and short enhancers in melanoma cell states

Mauduit, D.; Minnoye, L.; Taskiran, I. I.; De Waegeneer, M.; Christiaens, V.; Hulselmans, G.; Demeulemeester, J.; Wouters, J.; Aerts, S.

10.1101/2021.07.27.453936 — genomics — Posted on 2021-07-27

578 Evolution of binding preferences among whole-genome duplicated transcription factors

Gera, T.; Jonas, F.; More, R.; Barkai, N.

10.1101/2021.07.27.453962 — genomics — Posted on 2021-07-27

579 A novel anti-influenza combined therapy assessed by single cell RNA-sequencing

Medaglia, C.; Kolpakov, I.; Zhu, Y.; Constant, S.; Huang, S.; Zwygart, A. C.-A.; Cagno, V.; Dermitzakis, E.; Stellacci, F.; Xenarios, I.; Tapparel, C.

10.1101/2021.07.27.453967 — genomics — Posted on 2021-07-27

580 Development of an ASO therapy for Angelman syndrome by targeting an evolutionarily conserved region at the start of the UBE3A-AS transcript

Dindot, S. V.; Christian, S.; Murphy, W. J.; Berent, A.; Panagoulias, J.; Schlafer, A.; Ballard, J.; Radeva, K.; Robinson, R.; Myers, L.; Jepp, T.; Shaheen, H.; Hillman, P.; Konganti, K.; Hillhouse, A.; Bredemeyer, K. R.; Black, L.; Douville, J.; the FIRE consortium,

10.1101/2021.07.27.453820 — genetics — Posted on 2021-07-27

581 The role of trade-offs and feedbacks in shaping integrated plasticity, behavioral syndromes, and behavioral correlations

Dochtermann, N. A.

10.1101/2021.07.26.453877 — evolutionary biology — Posted on 2021-07-27

582 The effective family size of immigrant founders predicts their long-term demographic outcome: from Quebec settlers to their 20th-century descendants

Harding, T.; Milot, E.; Vezina, H.; Labuda, D.

10.1101/2021.07.25.453708 — evolutionary biology — Posted on 2021-07-27

583 Extracellular mechanical forces drive endocardial cell volume decrease during cardiac valve morphogenesis

Vermot, J.; Vignes, H.; Vagena-Pantoula, C.; Prakash, M.; Norden, C.; Jug, F.

10.1101/2021.07.27.453460 — developmental biology — Posted on 2021-07-27

584 Heterogeneity and dynamics of ERK and Akt activation by G protein-coupled receptors depend on the activated heterotrimeric G proteins

Chavez-Abiega, S.; Gronloh, M.; Gadella, T. W. J.; Bruggeman, F. J.; Goedhart, J.

10.1101/2021.07.27.453948 — cell biology — Posted on 2021-07-27

585 Mutated in Colorectal Cancer (MCC): a centrosomal protein that relocalizes to the ncMTOC during intestinal cell differentiation

Tomaz, L. B.; Liu, B. A.; Ong, S. L. M.; Tan, E. K.; M, M.; Tolwinski, N. S.; Williams, C. S.; Gingras, A.-C.; Leushacke, M.; Dunn, N. R.

10.1101/2021.07.27.453941 — cell biology — Posted on 2021-07-27

586 To bin or not to bin: analyzing single-cell growth data

Kar, P.; Tiruvadi-Krishnan, S.; Männik, J.; Männik, J.; Amir, A.

10.1101/2021.07.27.453901 — microbiology — Posted on 2021-07-27

587 Single-cell imaging of Pseudomonas reveals dynamic polar accumulation of the extracellular iron-scavenger pyoverdin

Moreno-Fenoll, C.; Ardre, M.; Rainey, P. B.

10.1101/2021.07.27.453990 — microbiology — Posted on 2021-07-27

588 CD8+ T Cell Metabolic Rewiring Defined by Single-Cell RNA-Sequencing Identifies a Critical Role of ASNS Expression Dynamics in T Cell Differentiation

Fernandez-Garcia, J.; Franco, F.; Parik, S.; Pane, A. A.; Broekaert, D.; Van Elsen, J.; Vermeire, I.; Van Brussel, T.; Schepers, R.; Modave, E.; Karakach, T.; Carmeliet, P.; Lambrechts, D.; Ho, P.-C.; Fendt, S.-M.

10.1101/2021.07.27.453976 — immunology — Posted on 2021-07-27

589 Nitrate-regulated growth processes involve activation of gibberellin pathway

Camut, L.; Gallova, B.; Jilli, L.; Sirlin-Josserand, M.; Carrera, E.; Sakvarelidze-Achard, L.; Zumsteg, J.; Heintz, D.; Ruffel, S.; Krouk, G.; Thomas, S. G.; Hedden, P.; Phillips, A. L.; Daviere, J.-M.; Achard, P.

10.1101/2021.07.27.453969 — plant biology — Posted on 2021-07-27

590 3D Convolutional Neural Networks for Classification of Alzheimer's and Parkinson's Disease with T1-Weighted Brain MRI

Dhinagar, N. J.; Thomopoulos, S. I.; Owens-Walton, C.; Stripelis, D.; Ambite, J.-L.; Ver Steeg, G.; Weintraub, D.; Cook, P.; McMillan, C.; Thompson, P. M.

10.1101/2021.07.26.453903 — bioinformatics — Posted on 2021-07-27

591 AlphaTims: Indexing trapped ion mobility spectrometry - time of flight data for fast and easy accession and visualization

Willems, S.; Voytik, E.; Skowronek, P.; Strauss, M. T.; Mann, M.

10.1101/2021.07.27.453933 — bioinformatics — Posted on 2021-07-27

592 Detection and characterization of replication origins defined by DNA polymerase epsilon

Jaksik, R.; Wheeler, D. A.; Kimmel, M.

10.1101/2021.07.27.453931 — genomics — Posted on 2021-07-27

593 Disordered climate threatens short-distance migrants

YANG, H.; Yu, L.; Qi, H.; Fu, S.; Wang, Y.; Yang, J.; Du, H.

10.1101/2021.07.27.453912 — ecology — Posted on 2021-07-27

594 Parental origin of Gsα inactivation differentially affects bone remodeling in a mouse model of Albright hereditary osteodystrophy

McMullan, P.; Yang, Q.; Maye, P.; Rowe, D.; Germain-Lee, E.

10.1101/2021.07.27.453811 — cell biology — Posted on 2021-07-27

595 Anaerobic biodegradation of chloroform and dichloromethane with a Dehalobacter enrichment culture

Wang, H.; Yu, R.; Webb, J.; Dollar, P.; Freedman, D. L.

10.1101/2021.07.26.453918 — microbiology — Posted on 2021-07-27

596 Uncoupling of the Diurnal Growth Program by Artificial Genome Relaxation in Synechocystis sp. PCC 6803

Behle, A.; Dietsch, M.; Goldschmidt, L.; Murugathas, W.; Brandt, D.; Busche, T.; Kalinowski, J.; Ebenhoeh, O.; Axmann, I. M.; Machne, R.

10.1101/2021.07.26.453758 — microbiology — Posted on 2021-07-27

597 Histone Variant macroH2A1 Spatially and Functionally Organizes Human Papillomavirus Replication Foci in the Productive Stage of Infection

Khurana, S.; Markowitz, T. E.; Kabat, J.; McBride, A. A.

10.1101/2021.07.27.453825 — microbiology — Posted on 2021-07-27

598 Spores and extracellular matrix components impart molecular order in Bacillus subtilis biofilms.

Azulay, D. N.; Spaeker, O.; Ghrayeb, M.; Wilsch-Brauninger, M.; Scoppola, E.; Burghammer, M.; Zizak, I.; Bertinetti, L.; Politi, Y.; Chai, L.

10.1101/2021.07.27.453653 — microbiology — Posted on 2021-07-27

599 Quantification of within patient Staphylococcus aureus phenotypic heterogeneity as a proxy for presence of persisters across clinical presentations

Baer, J.; Boumasmoud, M.; Mairpady Shambat, S.; Vulin, C.; Huemer, M.; Schweizer, T. A.; Gómez Mejia, A.; Eberhard, N.; Achermann, Y.; Zingg, P. O.; Mestres, C. A.; Brugger, S. D.; Schüpbach, R. A.; Kouyos, R. D.; Hasse, B.; Zinkernagel, A. S.

10.1101/2021.07.27.453929 — microbiology — Posted on 2021-07-27

600 The olfactory gating of visual preferences to human skin and colors in mosquitoes

Alonso San Alberto, D.; Rusch, C.; Zhan, Y.; Straw, A. D.; Montell, C.; Riffell, J. A.

10.1101/2021.07.26.453916 — neuroscience — Posted on 2021-07-27

601 Thalamic deep brain stimulation as a paradigm to reduce consciousness: implications for cortico-striatal dynamics, absence epilepsy and consciousness studies

Redinbaugh, M. J.; Afrasiabi, M.; Phillips, J. M.; Kambi, N. A.; Mohanta, S.; Saalmann, Y. B.

10.1101/2021.07.27.453855 — neuroscience — Posted on 2021-07-27

602 Molecular mechanism of the anti-lung cancer effect of Jin Ning Fang based on network pharmacology and experimental verification

Wu, C.; Yu, Q.; Shou, W.; Zhang, K.; Li, Y.; Guo, W.; Bao, Q.

10.1101/2021.07.26.453881 — cancer biology — Posted on 2021-07-27

603 Size of the cell nucleus and its effect on the chromatin structure in living cells.

Efremov, A. K.; Hovan, L.; Yan, J.

10.1101/2021.07.27.453925 — biophysics — Posted on 2021-07-27

604 Understanding SARS-CoV-2 budding through molecular dynamics simulations of M and E protein complexes

Collins, L. T.; Elkholy, T.; Mubin, S.; Williams, R.; Ezike, K.; Singhal, A.

10.1101/2021.07.26.453874 — biophysics — Posted on 2021-07-27

605 HyperChIP for identifying hypervariable signals across ChIP/ATAC-seq samples

Chen, H.; Tu, S.; Yuan, C.; Tian, F.; Zhang, Y.; Sun, Y.; Shao, Z.

10.1101/2021.07.27.453915 — bioinformatics — Posted on 2021-07-27

606 Determination of best Raman spectroscopy spatial offsets for transcutaneous bone quality assessments in human hands

Chen, K.; Massie, C.; Awad, H. A.; Berger, A. J.

10.1101/2021.07.26.453893 — bioengineering — Posted on 2021-07-27

607 Deep Learning Image Classification of Red Blood Cell Deformability

Lamoureux, E. S.; Islamzada, E.; Wiens, M. V. J.; Matthews, K.; Duffy, S. P.; Ma, H.

10.1101/2021.07.26.453886 — bioengineering — Posted on 2021-07-27

608 A mutation in the pmrD gene of Shigella flexneri abrogates functional PhoPQ-PmrD-PmrAB signaling and polymyxin B resistance

McPhee, J. B.; Huynh, R.

10.1101/2021.07.26.453917 — microbiology — Posted on 2021-07-27

609 Directed yeast genome evolution by controlled introduction of trans-chromosomic structural variations

Jia, B.; Jin, J.; Han, M.; Yuan, Y.-J.

10.1101/2021.07.26.453910 — synthetic biology — Posted on 2021-07-27

610 CASowary: CRISPR-Cas13 guide RNA predictor for transcript depletion

Krohannon, A.; Srivastava, M.; Rauch, S.; Srivastava, R.; Dickinson, B.; Janga, S. C.

10.1101/2021.07.26.453663 — bioinformatics — Posted on 2021-07-27

611 Transcriptomic Analysis of Human Skin Wound Healing and Rejuvenation Following Ablative Fractional Laser Treatment

Sherrill, J. D.; Finlay, D.; Binder, R. L.; Robinson, M. K.; Wei, X.; Tiesman, J. P.; Flagler, M. J.; Loftus, J. M.; Kimball, A. B.; Bascom, C. C.; Isfort, R. J.

10.1101/2021.07.26.453869 — bioinformatics — Posted on 2021-07-27

612 Self-supervised contrastive learning for integrative single cell RNA-seq data analysis

Han, W.; Cheng, Y.; Chen, J.; Zhong, H.; Hu, Z.; Chen, S.; Zong, L.; King, I.; Gao, X.; Li, Y.

10.1101/2021.07.26.453730 — bioinformatics — Posted on 2021-07-27

613 The relationships between structural organization, material properties, and loading conditions and the risk of fracture and fracture location in the femur

Bredbenner, T. L.

10.1101/2021.07.26.453913 — bioengineering — Posted on 2021-07-27

614 Engineering Viral Vectors for Acoustically Targeted Gene Delivery

Li, H.; Heath, J. E.; Trippett, J. S.; Shapiro, M. G.; Szablowski, J. O.

10.1101/2021.07.26.453904 — bioengineering — Posted on 2021-07-27

615 Novel modification by L/F-tRNA-protein transferase (LFTR) generates a Leu/N-degron ligand in Escherichia coli.

Ottofuelling, R. D.; Ninnis, R. L.; Truscott, K. N.; Dougan, D. A.

10.1101/2021.07.26.453911 — biochemistry — Posted on 2021-07-27

616 Spatio-temporal dynamics of intra-host variability in SARS-CoV-2 genomes

Pathak, A. K.; Mishra, G. P.; Uppili, B.; Walia, S.; Fatihi, S.; Abbas, T.; Banu, S.; Ghosh, A.; Kanampalliwar, A.; Jha, A.; Fatima, S.; Aggarwal, S.; Dhar, M. S.; Marwal, R.; V. S., R.; Ponnusamy, K.; Kabra, S.; Rakshit, P.; Bhoyar, R. C.; Jain, A.; Divakar, M. K.; Imran, M.; Faruq, M.; Sowpati, D. T.; Thukral, L.; Raghav, S. K.; Mukerji, M.

10.1101/2020.12.09.417519 — genomics — Posted on 2021-07-27

617 Soil fauna may buffer the negative effects of drought on alien plant invasion

Jin, H.; Chang, L.; van Kleunen, M.; Liu, Y.

10.1101/2021.07.26.453896 — ecology — Posted on 2021-07-27

618 Interactive effects of herbivory and the level and fluctuations of nutrient availability on dominance of alien plants in synthetic native communities

Li, Y.; Gao, Y.; van Kleunen, M.; Liu, Y.

10.1101/2021.07.26.453898 — ecology — Posted on 2021-07-27

619 Nociceptor subtypes are born continuously over DRG development peaking at E10.5 - E11.5.

Landy, M. A.; Goyal, M.; Lai, H. C.

10.1101/2021.07.26.453909 — developmental biology — Posted on 2021-07-27

620 Ultrastructural and functional analysis of extra-axonemal structures in trichomonads

Coceres, V. M.; Iriarte, L. S.; Miranda-Magalhaes, A.; de Andrade, T. A. S.; de Miguel, N.; Pereira-Neves, A.

10.1101/2021.07.26.453887 — cell biology — Posted on 2021-07-27

621 Cognitive process modeling addresses context independence violations in the ABCD Study stop-signal task

Weigard, A.; Matzke, D.; Tanis, C.; Heathcote, A.

10.1101/2021.07.26.453872 — neuroscience — Posted on 2021-07-27

622 AJILE12: Long-term naturalistic human intracranial neural recordings and pose

Peterson, S. M.; Singh, S. H.; Dichter, B.; Scheid, M.; Rao, R. P. N.; Brunton, B. W.

10.1101/2021.07.26.453884 — neuroscience — Posted on 2021-07-27

623 Spike protein cleavage-activation mediated by the SARS-CoV-2 P681R mutation: a case-study from its first appearance in variant of interest (VOI) A.23.1 identified in Uganda

Lubinski, B.; Frazier, L.; Phan, M.; Bugumbe, D.; Tang, T.; Daniel, S.; Cotten, M.; Jaimes, J. A.; Whittaker, G.

10.1101/2021.06.30.450632 — microbiology — Posted on 2021-07-27

624 Mechanism of a COVID-19 nanoparticle vaccine candidate that elicits a broadly neutralizing antibody response to SARS-CoV-2 variants

Zhang, Y.-N.; Paynter, J.; Sou, C.; Fourfouris, T.; Wang, Y.; Abraham, C.; Ngo, T.; Zhang, Y.; He, L.; Zhu, J.

10.1101/2021.03.26.437274 — immunology — Posted on 2021-07-27

625 MicroRNA childhood Cancer Catalog (M3Cs): A Resource for Translational Bioinformatics Toward Health Informatics in Pediatric Cancer.

Rashed, W. M.; Adel, F.; Rezk, M. A.; Basiouny, L.; Rezk, A. A.; Abdel-Razek, A. H.

10.1101/2021.07.26.452794 — bioinformatics — Posted on 2021-07-27

626 Contribution of 3D genome topological domains to genetic risk of cancers

Jablonski, K. P.; Carron, L.; Mozziconacci, J.; Forne, T.; Hütt, M.-T.; Lesne, A.

10.1101/2021.07.26.453813 — genetics — Posted on 2021-07-27

627 Newly identified parasitic nematode beta-tubulin alleles confer resistance to benzimidazoles

Dilks, C.; Koury, E.; Buchanan, C.; Andersen, E.

10.1101/2021.07.26.453836 — genetics — Posted on 2021-07-27

628 Airborne environmental DNA metabarcoding for the monitoring of terrestrial insects - a proof of concept

Roger, F.; Ghanavi, H.; Danielsson, N. N.; Wahlberg, N.; Löndahl, J.; Pettersson, L. B.; Andersson, G. K. S.; Boke-Olen, N.; Clough, Y.

10.1101/2021.07.26.453860 — ecology — Posted on 2021-07-27

629 A SUMO-dependent regulatory switch connects the piRNA pathway to the heterochromatin machinery in Drosophila

Andreev, V. I.; Yu, C.; Wang, J.; Schnabl, J.; Tirian, L.; Gehre, M.; Handler, D.; Duchek, P.; Novatchkova, M.; Baumgartner, L.; Meixner, K.; Sienski, G.; Patel, D. J.; Brennecke, J.

10.1101/2021.07.27.453956 — molecular biology — Posted on 2021-07-27

630 A dual barcoding approach to bacterial strain nomenclature: Genomic taxonomy of Klebsiella pneumoniae strains

Hennart, M.; Guglielmini, J.; Maiden, M. C. J.; Jolley, K. A.; Criscuolo, A.; Brisse, S.

10.1101/2021.07.26.453808 — microbiology — Posted on 2021-07-27

631 Kveik brewing yeasts demonstrate wide flexibility in beer fermentation temperature and flavour metabolite production and exhibit enhanced trehalose accumulation

Foster, B.; Tyrawa, C.; Ozsahin, E.; Lubberts, M.; Krogerus, K.; Preiss, R.; van der Merwe, G.

10.1101/2021.07.26.453768 — microbiology — Posted on 2021-07-27

632 A novel mobile RND-type efflux pump gene cluster, tmexC3D2-toprJ3, confers tigecycline resistance in Pseudomonas alcaligenes

Maehana, S.; Eda, R.; Niida, N.; Hirabayashi, A.; Sakai, K.; Furukawa, T.; Sei, K.; Kitasato, H.; Suzuki, M.

10.1101/2021.07.26.453812 — microbiology — Posted on 2021-07-27

633 Alzheimer's Disease Classification Accuracy is Improved by MRI Harmonization based on Attention-Guided Generative Adversarial Networks

sinha, s.; Thomopoulos, S. I.; Lam, P.; Muir, A.; Thompson, P. M.

10.1101/2021.07.26.453862 — neuroscience — Posted on 2021-07-27

634 TCF12 controls oligodendroglial cell proliferation and regulates signaling pathways conserved in gliomas

Archontidi, S.; Marie, C.; Gyorgy, B.; Guegan, J.; Sanson, M.; Parras, C.; Huillard, E.

10.1101/2021.07.26.453859 — neuroscience — Posted on 2021-07-27

635 Cell-specific expression buffering promotes cell survival and cancer robustness

Lin, H.-K.; Cheng, J.-H.; Wu, C.-C.; Hsieh, F.-S.; Dunlap, C. A.; Chen, S.-h.

10.1101/2021.07.26.453775 — systems biology — Posted on 2021-07-27

636 Individual repeatability, species differences, and the influence of socio-ecological factors on neophobia in 10 corvid species

Miller, R.; Lambert, M. L.; Frohnwieser, A.; Brecht, K. F.; Bugnyar, T.; Crampton, I.; Garcia-Pelegrin, E.; Gould, K.; Greggor, A. L.; Izawa, E.-I.; Kelly, D. M.; Li, Z.; Luo, Y.; Luong, L. B.; Massen, J. J. M.; Neider, A.; Reber, S. A.; Schiestl, M.; Seguchi, A.; Sepehri, P.; Stevens, J. R.; Taylor, A. H.; Wang, L.; Wolff, L. M.; Zhang, Y.; Clayton, N. S.

10.1101/2021.07.27.453788 — animal behavior and cognition — Posted on 2021-07-27

637 Water-soluble tocopherol derivatives inhibit SARS-CoV-2 RNA-dependent RNA polymerase

Pacl, H. T.; Tipper, J. L.; Sevalkar, R. R.; Crouse, A.; Crowder, C.; UAB Precision Medicine Institute, ; Ahmad, S.; Ahmad, A.; Holder, G. D.; Kuhlman, C. J.; Chinta, K. C.; Nadeem, S.; Green, T. J.; Petit, C. M.; Steyn, A. J.; Might, M.; Harrod, K. S.

10.1101/2021.07.13.449251 — microbiology — Posted on 2021-07-27

638 Bayesian Inference of Joint Coalescence Times for Sampled Sequences

Simon, H. E.; Huttley, G. A.

10.1101/2021.07.23.453461 — genetics — Posted on 2021-07-27

639 Selective ancestral sorting and de novo evolution in the agricultural invasion of Amaranthus tuberculatus

Kreiner, J. M.; Caballero, A.; Wright, S. I.; Stinchcombe, J. R.

10.1101/2021.07.26.453853 — evolutionary biology — Posted on 2021-07-27

640 De novo disease-associated mutations in KIF1A dominant negatively inhibit axonal transport of synaptic vesicle precursors

Anazawa, Y.; Kita, T.; Hayashi, K.; Niwa, S.

10.1101/2021.07.22.453457 — cell biology — Posted on 2021-07-27

641 Sexually distinct song cultures in a songbird metapopulation

Webb, W. H.; Roper, M. M.; Pawley, M. D.; Fukuzawa, Y.; Harmer, A. M.; Brunton, D. H.

10.1101/2021.07.05.451205 — animal behavior and cognition — Posted on 2021-07-27

642 Segmenting biological specimens from photos to understand the evolution of UV plumage in passerine birds

He, Y.; Cooney, C. R.; Varley, Z. K.; Nouri, L. O.; Moody, C. J. A.; Jardine, M. D.; Maddock, S.; Thomas, G. H.

10.1101/2021.07.22.453339 — evolutionary biology — Posted on 2021-07-27

643 Quantitative Profiling of Adaptation to Cyclin E Overproduction

Limas, J. C.; Littlejohn, A. N.; House, A. M.; Kedziora, K. M.; Fleifel, D.; Mouery, B. L.; Walens, A.; Aleman, M. M.; Dominguez, D.; Cook, J. G.

10.1101/2021.07.26.453751 — cell biology — Posted on 2021-07-27

644 Known mechanisms account for less than half of antimicrobial resistance in a diverse collection of non-aureus staphylococci.

Felgate, H.; Crossman, L. C.; Gray, E.; Clifford, R.; Wain, J.; Langridge, G. C.; Correia, A.

10.1101/2021.06.22.449369 — microbiology — Posted on 2021-07-27

645 Systematic analysis of the R2R3-MYB family of transcription factors in Camellia sinensis: evidence for species-specific catechin biosynthesis regulation

Li, J.; Liu, S.; Chen, P.; Cai, J.; Tang, S.; Yang, W.; Cao, F.; Zheng, P.; Sun, B.

10.1101/2021.07.21.453189 — plant biology — Posted on 2021-07-27

646 Representational learning of brain responses in executive function and higher-order cognition using deep graph convolutions

Zhang, Y.; Farrugia, N. e.; Dagher, A.; Bellec, P.

10.1101/2021.07.26.453914 — neuroscience — Posted on 2021-07-27

647 Remodeling of organelles and microtubules during spermiogenesis in the liverwort Marchantia polymorpha

Minamino, N.; Norizuki, T.; Mano, S.; Ebine, K.; Ueda, T.

10.1101/2021.07.10.451882 — plant biology — Posted on 2021-07-27

648 The presence of corticomuscular coherence during unipedal stance

Alkaff, S. D.; Ushiyama, J.

10.1101/2021.07.12.452017 — neuroscience — Posted on 2021-07-27

649 De novo macrocyclic peptides for inhibiting, stabilising and probing the function of the Retromer endosomal trafficking complex

Chen, K.-E.; Guo, Q.; Hill, T. A.; Cui, Y.; Kendall, A. K.; Yang, Z.; Hall, R. J.; Healy, M.; Sacharz, J.; Norwood, S. J.; Fonseka, S.; Xie, B.; Reid, R. C.; Leneva, N.; Parton, R. G.; Ghai, R.; Stroud, D. A.; Fairlie, D. P.; Suga, H.; Jackson, L. P.; Teasdale, R. D.; Passioura, T.; Collins, B. M.

10.1101/2020.12.03.410779 — biochemistry — Posted on 2021-07-27

650 Nano-analytical Characterization of Breast Tissue Biopsies Reveals an Association between Spherical Nano and Micro Particles and Invasive Malignant Breast Tumours.

Tsolaki, E.; Doran, W.; Overbeck, J.; Magnani, L.; Olivo, A.; Herrmann, I. K.; Bertazzo, S.

10.1101/2020.04.29.067660 — cancer biology — Posted on 2021-07-26

651 CIGB-300 synthetic peptide, an antagonist of CK2 kinase activity, as a treatment for Covid-19. A computational biology approach

Miranda, J.; Bringas, R.; de-Cossio, J. F.; Perera, Y.

10.1101/2021.07.26.453805 — bioinformatics — Posted on 2021-07-26

652 Genetic loci of the R. anatipestifer serotype discovered by Pan-GWAS and its application for the development of a multiplex PCR serotyping method

Yang, Z.; Yang, X.; Wang, M.; Jia, R.; Chen, S.; Liu, M.; Zhao, X.; Yang, Q.; Wu, Y.; Zhang, S.; Ou, X.; Mao, S.; Gao, Q.; Sun, D.; Zhu, D.; Cheng, A.

10.1101/2021.07.26.453894 — genomics — Posted on 2021-07-26

653 Resistance to a CRISPR-based gene drive at an evolutionarily conserved site is revealed by mimicking genotype fixation

Fuchs, S.; Garrood, W. T.; Beber, A.; Hammond, A.; Galizi, R.; Gribble, M.; Morselli, G.; Hui, T.-Y. J.; Willis, K.; Kranjc, N.; Burt, A.; Nolan, T.; Crisanti, A.

10.1101/2021.07.26.453797 — genetics — Posted on 2021-07-26

654 Bmmp influences wing shape by regulating anterior-posterior and proximal-distal axis development

Zou, Y.; Ding, X.; Zhang, L.; Xu, L.; Liang, S.; Hu, H.; Dai, F.; Tong, X.

10.1101/2021.07.26.453796 — genetics — Posted on 2021-07-26

655 Precise in vivo functional analysis of DNA variants with base editing using ACEofBASEs target prediction

Cornean, A.; Gierten, J.; Welz, B.; Mateo, J. L.; Thumberger, T.; Wittbrodt, J.

10.1101/2021.07.26.453883 — genetics — Posted on 2021-07-26

656 Joint interactions with humans may pose a higher risk of zoonotic outbreaks than interactions with conspecifics among wildlife populations at human-wildlife interfaces

Balasubramaniam, K. N.; Aiempichitkijkarn, N.; Kaburu, S. S. K.; Marty, P. R.; Beisner, B. A.; Bliss-Moreau, E.; Arlet, M. E.; Atwill, E. R.; McCowan, B.

10.1101/2021.07.19.452944 — ecology — Posted on 2021-07-26

657 Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production

Hulme, B.; Geyer, K.; Forde-Thomas, J.; Padalino, G.; Phillips, D.; Ittiprasert, W.; Karinshak, S.; Mann, V.; Chalmers, I.; Brindley, P.; Hokke, C.; Hoffmann, K. F.

10.1101/2021.07.26.453800 — molecular biology — Posted on 2021-07-26

658 Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens

Martin, G.; Russell, R. A.; Mundsperger, P.; Harris, S. L.; Li Jovanoska, L.; Farache Trajano, L.; Schiffner, T.; Fabian, K.; Tolazzi, M.; Scarlatti, G.; McFarlane, L. R.; Cheeseman, H.; Aldon, Y.; van Breemen, M. J.; Sliepen, K.; Katinger, D.; Kunert, R.; Sanders, R.; Shattock, R.; Ward, A.; Sattentau, Q. J.

10.1101/2021.07.26.453798 — molecular biology — Posted on 2021-07-26

659 ADAP1 promotes latent HIV-1 reactivation by selectively tuning a T cell signaling-transcriptional axis

Ramirez, N. G.; Lee, J.; Zheng, Y.; Li, L.; Dennis, B.; Chen, D.; Challa, A.; Planelles, V.; Westover, K. D.; Alto, N.; D'Orso, I.

10.1101/2021.07.26.453250 — microbiology — Posted on 2021-07-26

660 Antimicrobial activity of flavonoids glycosides and pyrrolizidine alkaloids from propolis of Scaptotrigona aff. postica.

Campos, T. M. C.; Junior, P. I. d. S.; Negri, G.; do Nascimento, R. M.; Mendonca, R. Z.

10.1101/2021.07.01.450350 — microbiology — Posted on 2021-07-26

661 The determinants of African Swine Fever Virus Virulence - the Georgia 2007/1 strain and the host macrophage response

Cackett, G.; Portugal, R.; Matelska, D.; Dixon, L.; Werner, F.

10.1101/2021.07.26.453801 — microbiology — Posted on 2021-07-26

662 Regulatory cross-talk supports resistance to Zn intoxication in Streptococcus

Sullivan, M. J.; Goh, K. G.; Ulett, G. C.

10.1101/2021.07.26.453799 — microbiology — Posted on 2021-07-26

663 Cell-type specific innate immune responses shape rabies virus tropism

Feige, L.; Kozaki, T.; Dias de Melo, G.; Guillemot, V.; Larrous, F.; Ginhoux, F.; Bourhy, H.

10.1101/2021.07.26.453802 — microbiology — Posted on 2021-07-26

664 The WOPR family protein Ryp1 is a key regulator of gene expression, development, and virulence in the thermally dimorphic fungal pathogen Coccidioides posadasii

Mandel, A.; Beyhan, S.; Voorhies, M.; Shubitz, L. F.; Galgiani, J.; Orbach, M. J.; Sil, A.

10.1101/2021.07.26.453804 — microbiology — Posted on 2021-07-26

665 CAR/CXCR5-T cell immunotherapy is safe and potentially efficacious in promoting sustained remission of SIV infection

Pampusch, M. S.; Abdelaal, H. M.; Cartwright, E. K.; Molden, J. S.; Davey, B. C.; Sauve, J. D.; Rendahl, A. K.; Rakasz, E. G.; Connick, E.; Berger, E. A.; Skinner, P. J.

10.1101/2021.07.26.453803 — immunology — Posted on 2021-07-26

666 Anipose: a toolkit for robust markerless 3D pose estimation

Karashchuk, P.; Rupp, K. L.; Dickinson, E. S.; Walling-Bell, S.; Sanders, E.; Azim, E.; Brunton, B.; Tuthill, J. C.

10.1101/2020.05.26.117325 — neuroscience — Posted on 2021-07-26

667 Data Augmentation Through Monte Carlo Arithmetic Leads to More Generalizable Classification in Connectomics

Kiar, G.; Chatelain, Y.; Salari, A.; Evans, A. C.; Glatard, T.

10.1101/2020.12.16.423084 — neuroscience — Posted on 2021-07-26

668 Prolonged Pain Reliably Slows Peak Alpha Frequency by Reducing Fast Alpha Power

Furman, A. J.; Prokhorenko, M.; Keaser, M. L.; Zhang, J.; Chen, S.; Mazaheri, A.; Seminowicz, D. A.

10.1101/2021.07.22.453260 — neuroscience — Posted on 2021-07-26

669 Recording and neural circuit-based manipulation of the maternal oxytocin pulses in mice

Yukinaga, H.; Hagihara, M.; Tsujimoto, K.; Chiang, H.-L.; Kato, S.; Kobayashi, K.; Miyamichi, K.

10.1101/2021.07.26.453888 — neuroscience — Posted on 2021-07-26

670 Attentional Modulation of Hierarchical Speech Representations in a Multitalker Environment

Kiremitci, I.; Yilmaz, O.; Celik, E.; Shahdloo, M.; Huth, A. G.; Cukur, T.

10.1101/2020.12.05.412957 — neuroscience — Posted on 2021-07-26

671 Modular assembly of dynamic models in systems biology

Pan, M.; Gawthrop, P. J.; Cursons, J.; Crampin, E.

10.1101/2021.07.26.453900 — systems biology — Posted on 2021-07-26

672 Gametophyte genome activation occurs at pollen mitosis I in maize

Nelms, B.; Walbot, V.

10.1101/2021.07.26.453871 — plant biology — Posted on 2021-07-26

673 Applications of the indole-alkaloid gramine shape the prokaryotic microbiota thriving at the barley root-soil interface

Maver, M.; Escudero-Martinez, C.; Abbott, J.; Morris, J.; Hedley, P. E.; Mimmo, T.; Bulgarelli, D.

10.1101/2020.12.07.414870 — plant biology — Posted on 2021-07-26

674 Coil-to-Helix Transition at the Nup358-BicD2 Interface Activates BicD2 for Dynein Recruitment

Gibson, J. M.; Cui, H.; Ali, M. Y.; Zhao, X.; Debler, E. W.; Zhao, J.; Trybus, K. M.; Solmaz, S. R.; Wang, C.

10.1101/2021.05.06.443034 — biophysics — Posted on 2021-07-26

675 preciseTAD: A transfer learning framework for 3D domain boundary prediction at base-pair resolution

Stilianoudakis, S.; Marshall, M. A.; Dozmorov, M. G.

10.1101/2020.09.03.282186 — bioinformatics — Posted on 2021-07-26

676 Inference of tissue relative proportions of the breast epithelial cell types luminal progenitor, basal, and luminal mature

Bartlett, T. E.; Chandna, S.; Roy, S.

10.1101/2021.05.17.444493 — bioinformatics — Posted on 2021-07-26

677 Protein Kinase C gamma Mutations Drive Spinocerebellar Ataxia Type 14 by Impairing Autoinhibition

Pilo, C. A.; Kornev, A. P.; Baffi, T. R.; Kunkel, M. T.; Malfavon, M.; Chen, D.-H.; Huang, L.-C.; Longman, C.; Kannan, N. A.; Raskind, W. H.; Gonzalez, D. J.; Taylor, S. S.; Gorrie, G.; Newton, A. C.

10.1101/2021.06.24.449810 — biochemistry — Posted on 2021-07-26

678 Divining Deamidation and Isomerization in Therapeutic Proteins: Effect of Neighboring Residue

Irudayanathan, F. J.; Zarzar, J.; Lin, J.; Izadi, S.

10.1101/2021.07.26.453885 — biochemistry — Posted on 2021-07-26

679 Honeybee cognition as a tool for scientific engagement

Denton, J. A.; Koludarov, I.; Thompson, M.; Bryk, J.; Velasque, M.

10.1101/2021.05.08.442068 — animal behavior and cognition — Posted on 2021-07-26

680 Sexually distinct song cultures in a songbird metapopulation

Webb, W. H.; Roper, M. M.; Pawley, M. D.; Fukuzawa, Y.; Harmer, A. M.; Brunton, D. H.

10.1101/2021.07.05.451205 — animal behavior and cognition — Posted on 2021-07-26

681 Improving long-read consensus sequencing accuracy with deep learning

Lal, A.; Brown, M.; Mohan, R.; Daw, J.; Drake, J.; Israeli, J.

10.1101/2021.06.28.450238 — genomics — Posted on 2021-07-26

682 Hidden genetic variation in plasticity increases the potential to adapt to novel environments

Walter, G. M.; Clark, J.; Terranova, D.; Cozzolino, S.; Cristaudo, A.; Hiscock, S. J.; Bridle, J. R.

10.1101/2020.10.26.356451 — evolutionary biology — Posted on 2021-07-26

683 Joint effects of genes underlying a temperature specialization tradeoff in yeast

AlZaben, F.; Chuong, J. N.; Abrams, M. B.; Brem, R. B.

10.1101/2021.03.18.436093 — evolutionary biology — Posted on 2021-07-26

684 Probabilistic Evaluation of Null Models for West Nile Virus in the United States

Keyel, A. C.; Kilpatrick, A. M. M.

10.1101/2021.07.26.453866 — ecology — Posted on 2021-07-26

685 Pax6 loss alters the morphological and electrophysiological development of mouse prethalamic neurons

Tian, T.; Quintana-Urzainqui, I.; Kozic, Z.; Pratt, T.; Price, D. J.

10.1101/2021.03.22.436455 — developmental biology — Posted on 2021-07-26

686 Retinoic acid fluctuation activates an uneven, direction-dependent network-wide robustness response in early embryogenesis

Parihar, M.; Bendelac-Kapon, L.; Gur, M.; Abbou, T.; Belorkar, A.; Achanta, S.; Kinberg, K.; Vadigepalli, R.; Fainsod, A.

10.1101/2020.07.15.203794 — developmental biology — Posted on 2021-07-26

687 Modeling lung cell development using human pluripotent stem cells

Ngan, Z.; Quach, H.; Dierolf, J.; Laselva, O.; Lee, J.-A.; Huang, E. N.; Mangos, M.; Xia, S.; Wong, A. P.

10.1101/2021.07.16.452691 — developmental biology — Posted on 2021-07-26

688 Harnessing changes in open chromatin determined by ATAC-seq to generate insulin-responsive reporter constructs.

Merrill, C. B.; Montgomery, A. B.; Pabon, M. A.; Rodan, A. R.; Rothenfluh, A.

10.1101/2021.05.06.443010 — cell biology — Posted on 2021-07-26

689 A putative erm gene is present in ΔermB Clostridioides difficile isolates showing high levels of resistance to clindamycin

Ramirez Hernandez, V.; Ramirez Vargas, G.

10.1101/2020.11.20.391128 — microbiology — Posted on 2021-07-26

690 Rabies virus with a destabilization domain added to its nucleoprotein spreads between neurons only if the domain is removed

Jin, L.; Matsuyama, M.; Sullivan, H. A.; Zhu, M.; Lavin, T. K.; Hou, Y.; Lea, N. E.; Pruner, M. T.; Dam Ferdinez, M. L.; Wickersham, I. R.

10.1101/550640 — neuroscience — Posted on 2021-07-26

691 Dynamic transitions between neural states are associated with flexible task-switching during a memory task

Liu, W.; Kohn, N.; Fernandez, G.

10.1101/2020.07.04.188235 — neuroscience — Posted on 2021-07-26

692 Asymmetric learning facilitates human inference of transitive relations

Ciranka, S.; Linde-Domingo, J.; Padezhki, I.; Wicharz, C.; Wu, C. M.; Spitzer, B.

10.1101/2021.04.03.437766 — neuroscience — Posted on 2021-07-26

693 Between-subject prediction reveals a shared representational geometry in the rodent hippocampus

Chen, H.-T.; Manning, J. R.; van der Meer, M. A.

10.1101/2020.01.27.922062 — neuroscience — Posted on 2021-07-26

694 Single-cell chemical imaging of engineered strains reveals heterogeneity in fatty acid production

Tague, N.; Lin, H.; Lugagne, J.-B.; Burman, D.; Wong, W.; Cheng, J.-X.; Dunlop, M.

10.1101/2021.07.26.453865 — synthetic biology — Posted on 2021-07-26

695 A Wnt/β-catenin signaling driven adipocyte population required for beiging and glucose homeostasis

Liu, Z.; Chen, T.; Zhang, S.; Yang, T.; Gong, Y.; deng, H.-W.; Bai, D.; Tian, W.; Chen, Y.

10.1101/2021.01.14.426702 — physiology — Posted on 2021-07-26

696 PEGR: a flexible management platform for reproducible epigenomic and genomic research

Shao, D.; Kellogg, G.; Nematbakhsh, A.; Kuntala, P.; Mahony, S.; Pugh, B. F.; Lai, W. K.

10.1101/2021.07.26.453821 — bioinformatics — Posted on 2021-07-26

697 Nucleic Transformer: Deep Learning on Nucleic Acids with Self-attention and Convolutions

He, S.; Gao, B.; Sabnis, R.; Sun, Q.

10.1101/2021.01.28.428629 — bioinformatics — Posted on 2021-07-26

698 Resistance, resilience, and functional redundancy of freshwater bacterioplankton communities facing a gradient of agricultural stressors in a mesocosm experiment

Barbosa da Costa, N.; Fugere, V.; Hebert, M.-P.; Xu, C. C. Y.; Barrett, R. D. H.; Beisner, B.; Bell, G.; Yargeau, V.; Fussmann, G. F.; Gonzalez, A.; Shapiro, B. J.

10.1101/2020.04.12.038372 — ecology — Posted on 2021-07-26

699 Krüppel-like factor gene function in the ctenophore Mnemiopsis leidyi assessed by CRISPR/Cas9-mediated genome editing

Presnell, J. S.; Browne, W. E.

10.1101/527002 — developmental biology — Posted on 2021-07-26

700 MYC hyperactivates WNT signaling in APC/CTNNB1-mutated colorectal cancer cells through miR-92a-dependent repression of DKK3

Sehgal, P.; Lanauze, C.; Wang, X.; Hayer, K. E.; Torres-Diz, M.; Sela, Y.; Stanger, B. Z.; Lengner, C. J.; Thomas-Tikhonenko, A.

10.1101/2021.07.26.453875 — cancer biology — Posted on 2021-07-26

701 The Alzheimer's gene SORL1 is a key regulator of endosomal recycling in human neurons

Mishra, S.; Knupp, A.; Szabo, M.; Kinoshita, C.; Hailey, D. W.; Wang, Y.; Young, J. E.

10.1101/2021.07.26.453861 — cell biology — Posted on 2021-07-26

702 Selfish bacteria are active throughout the water column of the ocean

Giljan, G.; Brown, S.; Lloyd, C. C.; Ghobrial, S.; Amann, R.; Arnosti, C.

10.1101/2021.07.26.453833 — microbiology — Posted on 2021-07-26

703 Effect of stimulation time on the expression of human macrophage polarization markers

Unuvar Purcu, D.; Korkmaz, A.; Gunalp, S.; Helvaci, D. G.; Erdal, Y.; Dogan, Y.; Wingender, G.; Sag, D.

10.1101/2021.07.26.453762 — immunology — Posted on 2021-07-26

704 Effects of theta transcranial alternating current stimulation (tACS) on exploration and exploitation during uncertain decision-making

Wischnewski, M.; Compen, B.

10.1101/2021.07.26.453851 — neuroscience — Posted on 2021-07-26

705 A single exposure to altered auditory feedback causes observable sensorimotor adaptation in speech

Hantzsch, L.; Parrell, B.; Niziolek, C. A.

10.1101/2021.07.26.453857 — neuroscience — Posted on 2021-07-26

706 A neuronal code for space in hippocampal coactivity dynamics independent of place fields

Levy, E. R. J.; Park, E. H.; Redman, W. T.; Fenton, A. A.

10.1101/2021.07.26.453856 — neuroscience — Posted on 2021-07-26

707 Trehalose induces tomato defenses and increases drought tolerance and bacterial wilt disease resistance

MacIntyre, A. M.; Meline, V.; Gorman, Z.; Augustine, S. P.; Dye, C. J.; Hamilton, C. D.; Iyer-Pascuzzi, A. S.; Kolomiets, M. V.; McCulloh, K. A.; Allen, C.

10.1101/2021.07.26.453814 — plant biology — Posted on 2021-07-26

708 Correcting machine learning models using calibrated ensembles with "mlensemble"

Konopka, T.

10.1101/2021.07.26.453832 — bioinformatics — Posted on 2021-07-26

709 Counting actin in contractile rings reveals novel contributions of cofilin and type II myosins to fission yeast cytokinesis

Chen, Q.; Malla, M.; Pollard, T. D.

10.1101/2021.07.26.453848 — cell biology — Posted on 2021-07-26

710 Protection of human ACE2 transgenic Syrian hamsters from SARS CoV-2 variants by human polyclonal IgG from hyper-immunized transchromosomic bovines

Gilliland, T.; Liu, Y.; Li, R.; Dunn, M.; Cottle, E.; Terada, Y.; Ryckman, Z.; Alcorn, M.; Vasilatos, S.; Lundy, J. D.; Larson, D.; Wu, H.; Luke, T.; Bausch, C.; Egland, K.; Sullivan, E.; Wang, Z.; Klimstra, W.

10.1101/2021.07.26.453840 — microbiology — Posted on 2021-07-26

711 Untangling Microbiota Diversity and Assembly Patterns in the World's Largest Water Diversion Canal

Zhang, L.; Yin, W.; Wang, C.; Zhang, A.; Zhang, H.; Zhang, T.; Ju, F.

10.1101/2021.07.26.453773 — microbiology — Posted on 2021-07-26

712 Caldendrin represses neurite regeneration via a sex-dependent mechanism in sensory neurons

Lopez, J. A.; Yamamoto, A.; Vecchi, J. T.; Hagen, J.; Lee, A.

10.1101/2021.07.26.453831 — neuroscience — Posted on 2021-07-26

713 Inseparable color and form in mouse visual cortex described by random pooling from rods and cones

Rhim, I.; Nauhaus, I.

10.1101/2021.07.26.453648 — neuroscience — Posted on 2021-07-26

714 ETAS(R)50 Attenuates SARS-CoV-2 Spike Protein-Induced IL-6 and IL-1β Production by Suppressing p44/42 MAPK and Akt Phosphorylation in Murine Primary Macrophages

Shirato, K.; Takanari, J.; Kizaki, T.

10.1101/2021.07.25.453717 — pharmacology and toxicology — Posted on 2021-07-26

715 AMaLa: analysis of Directed Evolution experiments via Annealed Mutational approximated Landscape

Sesta, L.; Uguzzoni, G.; Ferndadez-de-Cossio-Diaz, J.; Pagnani, A.

10.1101/2021.07.26.453757 — biophysics — Posted on 2021-07-26

716 SIRV: Spatial inference of RNA velocity at the single-cell resolution

Abdelaal, T.; Lelieveldt, B. P. F.; Reinders, M. J. T.; Mahfouz, A.

10.1101/2021.07.26.453774 — bioinformatics — Posted on 2021-07-26

717 Using topic modeling to detect cellular crosstalk in scRNA-seq

Pancheva, A.; Wheadon, H.; Rogers, S.; Otto, T.

10.1101/2021.07.26.453767 — bioinformatics — Posted on 2021-07-26

718 Correlational networking guides the discovery of cryptic proteases for lanthipeptide maturation

Xue, D.; Older, E. A.; Zhong, Z.; Shang, Z.; Chen, N.; Walla, M. D.; Dong, S.-H.; Tang, X.; Nagarkatti, P.; Nagarkatti, M.; Li, Y.-X.; Li, J.

10.1101/2021.07.26.453782 — biochemistry — Posted on 2021-07-26

719 Different contribution of the monkey prefrontal and premotor dorsal cortex in decision-making supported by inferential reasoning

Ramawat, S.; Mione, V.; Di Bello, F.; Bardella, G.; Genovesio, A.; Pani, P.; Ferraina, S.; Brunamonti, E.

10.1101/2021.07.26.453792 — animal behavior and cognition — Posted on 2021-07-26

720 The benefits of merging passive and active tracking approaches: new insights into riverine migration by salmonid smolts

Chavarie, L.; Honkanen, H. M.; Newton, M.; Lilly, J. M.; Greetham, H. R.; Adams, C.

10.1101/2021.07.26.453807 — ecology — Posted on 2021-07-26

721 The generation of a Bcl11a lineage tracing mouse model

Pensa, S.; Liu, P.; Khaled, W. T.

10.1101/2021.07.26.453822 — developmental biology — Posted on 2021-07-26

722 FH loss in RPE cells causes retinal degeneration in a human RPE-porcine retinal explant co-culture model

Armento, A.; Murali, A.; Marzi, J.; Arango-Gonzalez, B.; Kilger, E.; Clark, S. J.; Schenke-Layland, K.; Ramlogan-Steel, C. A.; Steel, J. C.; Ueffing, M.

10.1101/2021.07.26.453778 — cell biology — Posted on 2021-07-26

723 Increased aerosol transmission for B.1.1.7 (alpha variant) over lineage A variant of SARS-CoV-2

Port, J.; Yinda, K. C.; Avanzato, V.; Schulz, J.; Holbrook, M.; van Doremalen, N.; Shaia, C.; Fischer, R.; Munster, V.

10.1101/2021.07.26.453518 — microbiology — Posted on 2021-07-26

724 Characterizing enterotypes in human metagenomics: a viral perspective

song, l.; Zhang, L.; Fang, X.

10.1101/2021.07.26.453761 — microbiology — Posted on 2021-07-26

725 Temporal Dynamics of HCMV Gene Expression in Lytic and Latent Infections

Rozman, B.; Kitsberg, Y.; Nachshon, A.; Schwartz, M.; Stern-Ginossar, N.

10.1101/2021.07.26.453763 — microbiology — Posted on 2021-07-26

726 Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralising SARS-CoV-2 nanobodies

Hanke, L.; Sheward, D. J.; Pankow, A.; Perez Vidakovics, L.; Karl, V.; Kim, C.; Urgard, E.; Smith, N. L.; Astorga-Wells, J.; Ekström, S.; Coquet, J. M.; McInerney, G. M.; Murrell, B.

10.1101/2021.07.25.453673 — immunology — Posted on 2021-07-26

727 Affinity maturation for an optimal balance between long-term immune coverage and short-term resource constraints

Chardes, V.; Vergassola, M.; Walczak, A. M.; Mora, T.

10.1101/2021.07.26.453765 — immunology — Posted on 2021-07-26

728 Immunization with synthetic SARS-CoV-2 S glycoprotein virus-like particles protects Macaques from infection

Sulbaran, G.; Maisonnasse, P.; Amen, A.; Guilligay, D.; Bosquet, N.; Burger, J. A.; Poniman, M.; Buisson, M.; Dylon, S. D.; Naninck, T.; Lemaitre, J.; Gros, W.; Gallouet, A.-S.; Marlin, R.; Bouillier, C.; Contreras, V.; Relouzat, F.; Fenel, D.; Thepaut, M.; Bally, I.; Thielens, N.; Fieschi, F.; Schoehn, G.; van der Werf, S.; van Gils, M.; Sandres, R. W.; Poignard, P.; Le Grand, R.; Weissenhorn, W.

10.1101/2021.07.26.453755 — immunology — Posted on 2021-07-26

729 Regulatory start-stop elements in 5' untranslated regions pervasively modulate translation

Rendleman, J.; Mohammad, M. P.; Pressler, M.; Maity, S.; Hronova, V.; Gao, Z.; Herrmannova, A.; Lei, A.; Allgoewer, K.; Sultanov, D.; Hinckley, W. E.; Szkop, K.; Topisirovic, I.; Larsson, O.; Hatzoglou, M.; Valasek, L. S.; Vogel, C.

10.1101/2021.07.26.453809 — systems biology — Posted on 2021-07-26

730 Model predicts the impact of root system architecture on soil water infiltration.

Mair, A.; Dupuy, L. X.; Ptashnyk, M.

10.1101/2021.07.26.453789 — systems biology — Posted on 2021-07-26

731 The peroxisomal transporter ABCD3 plays a major role in dicarboxylic fatty acid metabolism

Ranea-Robles, P.; Chen, H.; Stauffer, B.; Yu, C.; Bhattacharya, D.; Friedman, S. L.; Puchowicz, M.; Houten, S.

10.1101/2021.07.26.452046 — physiology — Posted on 2021-07-26

732 Evaluating the feasibility and efficacy of a dual-modality nanoparticle contrast agent (Nanotrast-CF800) for image-guided sentinel lymph node mapping in the oral cavity of healthy dogs

Wan, J.; Oblak, M. L.; Ram, A. S.; McKenna, C.; Singh, A.; Nykamp, S.

10.1101/2021.07.26.453824 — cancer biology — Posted on 2021-07-26

733 A machine learning based analysis to probe the relationship between odorant structure and olfactory behaviour in C. elegans

Vishnoi, A.; Sharma, R.

10.1101/2021.07.26.453815 — biophysics — Posted on 2021-07-26

734 Differential Interactions Between Human ACE2 and Spike RBD of SARS-CoV-2 Variants of Concern

Kim, S.; Liu, Y.; Lei, Z.; Dicker, J.; Cao, Y.; Zhang, X. F.; Im, W.

10.1101/2021.07.23.453598 — biophysics — Posted on 2021-07-26

735 The structural role of bacterial eDNA in the formation of biofilm streamers

Secchi, E.; Savorana, G.; Vitale, A.; Eberl, L.; Stocker, R.; Rusconi, R.

10.1101/2021.07.26.453754 — biophysics — Posted on 2021-07-26

736 Mutations in two SARS-CoV-2 variants of concern reflect two distinct strategies of antibody escape

Fiedler, S.; Denninger, V.; Morgunov, A. S.; Ilsley, A.; Worth, R.; Meisl, G.; Xu, C. K.; Piziorska, M. A.; Ricci, F.; Malik, A. Y.; Devenish, S. R. A.; Schneider, M. M.; Kosmoliaptsis, V.; Aguzzi, A.; Iwasaki, A.; Fiegler, H.; Knowles, T. P. J.

10.1101/2021.07.23.453327 — biochemistry — Posted on 2021-07-26

737 N-glycosylation profiles of the SARS-CoV-2 spike D614G mutant and its ancestral protein characterized by advanced mass spectrometry

Wang, D.; Zhou, B.; Keppel, T.; Solano, M.; Baudys, J.; Goldstein, J.; Finn, M. G.; Fan, X.; Chapman, A. P.; Bundy, J.; Woolfitt, A. R.; Osman, S.; Pirkle, J. L.; Wentworth, D. E.; Barr, J. R.

10.1101/2021.07.26.453787 — biochemistry — Posted on 2021-07-26

738 NMR spectroscopy of a single mammalian embryo

Sivelli, G.; Conley, G. M.; Herrera, C.; Marable, K.; Rodriguez, K.; Bollwein, H.; Sudano, M.; Brugger, J.; Simpson, A.; Boero, G.; Marco, G.

10.1101/2021.07.26.453772 — biochemistry — Posted on 2021-07-26

739 COPILOT: a Containerised wOrkflow for Processing ILlumina genOtyping daTa

Patel, H.; Lee, S.-H.; Breen, G.; Menzel, S.; Ojewunmi, O.; Dobson, R.

10.1101/2021.07.26.453753 — genomics — Posted on 2021-07-26

740 A multispecies amplicon sequencing approach for genetic diversity assessment in grassland plant species

Loera-Sanchez, M.; Studer, B.; Koelliker, R.

10.1101/2021.07.26.453819 — ecology — Posted on 2021-07-26

741 Unraveling three-dimensional chromatin structural dynamics during spermatogonial differentiation

Zheng, Y.; Zhang, L.; Jin, L.; Zhang, P.; Li, F.; Guo, M.; Gao, Q.; Zeng, Y.; Li, M.; Zeng, W.

10.1101/2021.07.26.453830 — developmental biology — Posted on 2021-07-26

742 The extracellular matrix gene, Svep1, orchestrates airway patterning and the transition from lung branching morphogenesis to alveolar maturation in the mouse

Foxworth, N.; Wells, J.; Ocana-Lopez, S.; Muller, S.; Denegre, J.; Palmer, K.; McGee, T.; Memishian, W.; Murray, S. A.; Donahoe, P. K.; Bult, C. J.; Loscertales, M.

10.1101/2021.07.26.453586 — developmental biology — Posted on 2021-07-26

743 SARS-CoV-2 Delta variant pathogenesis and host response in Syrian hamsters

Mohandas, S.; Yadav, P. D.; Shete, A. A.; Nyayanit, D.; Sapkal, G. N.; Lole, K.; Gupta, N.

10.1101/2021.07.24.453631 — molecular biology — Posted on 2021-07-26

744 A bacterial dynamin-like protein confers a novel phage resistance strategy on the population level in Bacillus subtilis

Guo, L.; Sattler, L.; Graumann, P.; Bramkamp, M.

10.1101/2021.07.26.453760 — microbiology — Posted on 2021-07-26

745 Plasmid supercoiling decreases during the dark phase in cyanobacteria: a clarification of the interpretation of chloroquine-agarose gels.

Rüdiger, S.; Rediger, A.; Kölsch, A.; Dienst, D.; Axmann, I. M.; Machne, R.

10.1101/2021.07.26.453679 — microbiology — Posted on 2021-07-26

746 Synaptic Mechanisms of Top-Down Control by The Auditory Cortico-Collicular Pathway

Oberle, H. M.; Ford, A.; Czarny, J.; Apostolides, P. F.

10.1101/2021.07.26.453816 — neuroscience — Posted on 2021-07-26

747 The Role of Biofilms, Bacterial Phenotypes, and Innate Immune Response in Mycobacterium avium Colonization to Infection

Weathered, C.; Pennington, K.; Escalante, P.; Pienaar, E.

10.1101/2021.07.26.453817 — systems biology — Posted on 2021-07-26

748 Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma

Urtatiz, O.; Haage, A.; Tanentzapf, G.; Van Raamsdonk, C. D.

10.1101/2021.07.26.453858 — cancer biology — Posted on 2021-07-26

749 ABlooper: Fast accurate antibody CDR loop structure prediction with accuracy estimation

Abanades, B.; Georges, G.; Bujotzek, A.; Deane, C. M.

10.1101/2021.07.26.453747 — bioinformatics — Posted on 2021-07-26

750 Interstitial and cerebrospinal fluid exchanging process revealed by phase alternate labeling with null recovery MRI

Li, A. M.; Xu, J.

10.1101/2021.07.26.453795 — bioengineering — Posted on 2021-07-26

751 Global protein responses of multi-drug resistant plasmid containing Escherichia coli to ampicillin, cefotaxime, imipenem and ciprofloxacin.

Margalit, A.; Carolan, J. C.; Walsh, F.

10.1101/2021.07.26.453744 — microbiology — Posted on 2021-07-26

752 EMDA: A Python package for Electron Microscopy Data Analysis

Warshamanage, R.; Yamashita, K.; Murshudov, G. N.

10.1101/2021.07.26.453750 — biophysics — Posted on 2021-07-26

753 Molecular Learning of a Soft-Disks Fluid

Zammataro, L.

10.1101/2021.07.24.453642 — bioinformatics — Posted on 2021-07-26

754 Hoslundia opposita and other Nigerian plants inhibit sickle hemoglobin polymerization and prevent erythrocyte sickling: a virtual screening-guided identification of bioactive plants.

Olori, E. O.; Olubiyi, O. O.; Babalola, C. P.

10.1101/2021.07.25.453693 — bioinformatics — Posted on 2021-07-26

755 Structure and function of the ROR2 cysteine-rich domain in vertebrate noncanonical WNT5A signaling

Griffiths, S. C.; Tan, J.; Wagner, A.; Blazer, L. L.; Adams, J. J.; Sidhu, S. S.; Siebold, C.; Ho, H.-Y. H.

10.1101/2021.07.26.453829 — biochemistry — Posted on 2021-07-26

756 Barcoded RH-seq illuminates the complex genetic basis of yeast thermotolerance

Abrams, M. B.; Chuong, J. N.; AlZaben, F.; Dubin, C. A.; Skerker, J. M.; Brem, R. B.

10.1101/2021.07.26.453780 — evolutionary biology — Posted on 2021-07-26

757 The robustness of a simple dynamic model of island biodiversity to geological and eustatic change

Santos Neves, P.; Lambert, J. W.; Valente, L.; Etienne, R. S.

10.1101/2021.07.26.453064 — evolutionary biology — Posted on 2021-07-26

758 Identification of a new family of "megaphages" that are abundant in the marine environment

Michniewski, S.; Rihtman, B.; Cook, R.; Jones, M.; Wilson, W.; Scanlan, D. D.; Millard, A.

10.1101/2021.07.26.453748 — microbiology — Posted on 2021-07-26

759 A highly conserved lipase deacylates oxidized phospholipids and ameliorates acute lung injury

Zou, B.; Goodwin, M.; Saleem, D.; Jiang, W.; Tang, J.; Chu, Y.; Munford, R. S.; Lu, M.

10.1101/2021.07.26.453786 — immunology — Posted on 2021-07-26

760 Understanding associative false memories in aging using multivariate analyses

Dennis, N. A.; Overman, A. A.; Carpenter, C. M.; Gerver, C. R.

10.1101/2021.07.26.453271 — neuroscience — Posted on 2021-07-26

761 EXPRESSION OF A SECRETABLE, CELL-PENETRATING CDKL5 PROTEIN ENHANCES THE EFFICACY OF AAV VECTOR-MEDIATED GENE THERAPY FOR CDKL5 DEFICIENCY DISORDER.

Medici, G.; Tassinari, M.; Galvani, G.; Bastianini, S.; Gennaccaro, L.; Loi, M.; Fuchs, C.; Mottolese, N.; Alvente, S.; Berteotti, C.; Bagget, H. R.; Zoccoli, G.; Giustetto, M.; Muotri, A. R.; Nakai, H.; Trazzi, S.; Ciani, E.

10.1101/2021.07.26.453746 — neuroscience — Posted on 2021-07-26

762 Resiniferatoxin hampers the nocifensive response of Caenorhabditis elegans to noxious heat, and pathway analysis revealed that the Wnt signaling pathway is involved

Ben Salem, J.; Nkambeu, B.; Arvanitis, D.; Beaudry, F.

10.1101/2021.07.26.453516 — neuroscience — Posted on 2021-07-26

763 Delineating Medical Education: Bibliometric Research Approach(es)

Maggio, L. A.; Ninkov, A.; Frank, J. R.; Costello, J. A.; Artino, A. R.

10.1101/2021.07.23.453492 — scientific communication and education — Posted on 2021-07-26

764 Impact of neurite alignment on organelle motion.

Mytiliniou, M.; Wondergem, J. A. J.; Schmidt, T.; Heinrich, D.

10.1101/2021.07.26.453779 — biophysics — Posted on 2021-07-26

765 Towards an integrative multi-omics workflow

Jeanneret, F.; Gazut, S.

10.1101/2021.07.26.453736 — bioinformatics — Posted on 2021-07-26

766 Accelerated epigenetic aging and inflammatory/immunological profile (ipAGE) in patients with chronic kidney disease

Yusipov, I.; Kondakova, E.; Kalyakulina, A.; Krivonosov, M.; Lobanova, N.; Bacalini, M. G.; Franceschi, C.; Vedunova, M.; Ivanchenko, M.

10.1101/2021.07.23.453588 — bioinformatics — Posted on 2021-07-26

767 Evaluating Differences in Elastic Modulus of Regenerated and Uninjured Mouse Digit Bone through microCT Density-Elasticity Calculation and Nanoindentation Testing

Hoffseth, K. F.; Busse, E.; Lacey, M.; Sammarco, M. C.

10.1101/2021.07.26.453818 — bioengineering — Posted on 2021-07-26

768 Fusion-oncogenes are associated with increased metastatic capacity and persistent disease in pediatric thyroid cancers

Franco, A. T.; Ricarte-Filho, J. C.; Isaza, A.; Jones, Z.; Jain, N.; Mostoufi-Moab, S.; Surrey, L.; Laetsch, T. W.; Li, M. M.; DeHart, J. C.; Reichenberger, E.; Taylor, D.; Kazahaya, K.; Adzick, N. S.; Bauer, A. J.

10.1101/2021.07.23.453235 — genetics — Posted on 2021-07-26

769 The northern gene flow into southeastern East Asians inferred from genome-wide array genotyping

He, G.; Li, Y.; Zou, X.; Yeh, H.-Y.; Tang, R.; Wang, P.; Bai, J.; Yang, X.; Wang, Z.; Guo, J.; Chen, J.; Chen, J.; Yang, M.; Zhao, J.; Sun, J.; Zhu, K.; Ma, H.; Wang, R.; Yang, W.; Hu, R.; Wei, L.; Wang, M.; Chen, G.; Wang, C.-C.

10.1101/2021.07.25.453681 — genetics — Posted on 2021-07-26

770 Quantitative Profiling of Adaptation to Cyclin E Overproduction

Limas, J. C.; Littlejohn, A. N.; House, A. M.; Kedziora, K. M.; Fleifel, D.; Mouery, B. L.; Walens, A.; Aleman, M. M.; Dominguez, D.; Cook, J. G.

10.1101/2021.07.26.453751 — cell biology — Posted on 2021-07-26

771 Connectivity between the hippocampus and default mode network during the relief, but not elicitation, of curiositysupports curiosity-enhanced memory enhancements

Murphy, C.; Ranganath, C.; Gruber, M. J.

10.1101/2021.07.26.453739 — neuroscience — Posted on 2021-07-26

772 Inhibition of striatal SEZ6 by miR-3594-5p is a drug-specific marker for late-stage heroin intake escalation

Lenoir, M.; Bondi, I.; Clemenceau, L.; Nondier, I.; Balle, M.; Jacques, S.; Duche, A.; Canestrelli, C.; Martin-Lanneree, S.; Mouillet-Richard, S.; Gunnersen, J. M.; Ahmed, S. H.; Marie, N.; Noble, F.

10.1101/2021.07.26.453355 — neuroscience — Posted on 2021-07-26

773 Miniature inverted-repeat transposable elements drive rapid microRNA diversification in angiosperms

Guo, Z.; Kuang, Z.; Tao, Y.; Wang, H.; Wan, M.; Hao, C.; Shen, F.; Yang, X.; Li, L.

10.1101/2021.07.25.453727 — plant biology — Posted on 2021-07-26

774 The cryo-EM structure of the chloroplast ClpP complex reveals an interaction with the co-chaperonin complex that inhibits ClpP proteolytic activity

Wang, N.; Wang, Y.; Zhao, Q.; Zhang, X.; Peng, C.; Zhang, W.; Liu, Y.; Vallon, O.; Schroda, M.; Cong, Y.; Liu, C.

10.1101/2021.07.26.453741 — plant biology — Posted on 2021-07-26

775 Low affinity integrin states have faster binding kinetics than the high affinity state

Li, J.; Yan, J.; Springer, T. A.

10.1101/2021.07.26.453735 — biophysics — Posted on 2021-07-26

776 Taxonomic repositioning of twelve Xanthomonas campestris, seven Xanthomonas axonopodis and one Pseudomonas cissicola reference pathovars to Xanthomonas citri

Bansal, K.; Kumar, S.; Patil, P. B.

10.1101/2021.07.23.453582 — genomics — Posted on 2021-07-26

777 Intermittent hypoxia enhances the expression of HIF1A by increasing the quantity and catalytic activity of KDM4A-C and demethylating H3K9me3 at the HIF1A locus

Martinez, C.-A.; Bal, N.; Cistulli, P. A.; Cook, K. M.

10.1101/2021.07.25.453726 — cell biology — Posted on 2021-07-26

778 AGO1 regulates major satellite transcripts and H3K9me3 distribution at pericentromeric regions in mESCs

Mueller, M.; Faeh, T.; Schaefer, M.; Luitz, J.; Stalder, P.; Arora, R.; Ngondo, R. P.; Ciaudo, C.

10.1101/2021.07.26.453733 — cell biology — Posted on 2021-07-26

779 LAMP2A regulates the loading of proteins into exosomes.

Ferreira, J. V.; da Rosa Soares, A.; Ramalho, J. S.; Carvalho, C. M.; Cardoso, M. H.; Pintado, P.; Carvalho, A. S.; Beck, H. C.; Matthiesen, R.; Zuzarte, M.; Girao, H.; van Niel, G.; Pereira, P.

10.1101/2021.07.26.453637 — cell biology — Posted on 2021-07-26

780 Distinct mechanisms underlie H2O2 sensing in C. elegans head and tail

Quintin, S.; Aspert, T.; Charvin, G.

10.1101/2021.07.26.451501 — cell biology — Posted on 2021-07-26

781 A comprehensive collection of transcriptome data to support life cycle analysis of the poplar rust fungus Melampsora larici-populina

Guerillot, P.; Kohler, A.; Morin, E.; Louet, C.; Duplessis, S.

10.1101/2021.07.25.453710 — microbiology — Posted on 2021-07-26

782 Opposing roles of blood-borne monocytes and tissue-resident macrophages in limbal stem cell damage after ocular injury

Zhou, C.; Lei, F.; Mittermaier, M.; Ksander, B.; Dana, R.; Dohlman, C. H.; Vavvas, D. G.; Chodosh, J.; Paschalis, E. I.

10.1101/2021.07.25.453707 — immunology — Posted on 2021-07-26

783 Age- and sex-related topological organisation of human brain functional networks and their relationship to cognition

Foo, H.; Thalamuthu, A.; Jiang, J.; Koch, F. C.; Mather, K.; Wen, W.; Sachdev, P.

10.1101/2021.07.25.453293 — neuroscience — Posted on 2021-07-26

784 First record of Temnothorax convexus (Forel, 1894) in Portugal (Hymenoptera: Formicidae) with an updated checklist of ants from the country

Gonzalez, J. A.

10.1101/2021.07.25.453702 — zoology — Posted on 2021-07-26

785 The high-throughput gene prediction of more than 1,700 eukaryote genomes using the software package EukMetaSanity

Neely, C. J.; Hu, S. K.; Alexander, H.; Tully, B. J.

10.1101/2021.07.25.453296 — bioinformatics — Posted on 2021-07-26

786 IRI-CCE: A Platform for Evaluating CRISPR-based Genome Editing Tools and Its Components

Shelake, R. M.; Pramanik, D.; Kim, J.-Y.

10.1101/2021.07.25.453636 — bioengineering — Posted on 2021-07-26

787 Dynamics of SARS-CoV-2 mutations reveals regional-specificity and similar trends of N501 and High-Frequency mutation N501Y in different levels of control measures

Justo Arevalo, S.; Zapata Sifuentes, D.; Huallpa, C. J.; Landa Bianchi, G.; Castillo Chavez, A.; Garavito-Salini Casas, R.; Uribe Calampa, C. S.; Uceda-Campos, G.; Pineda Chavarria, R.

10.1101/2021.06.01.446571 — genomics — Posted on 2021-07-26

788 The first crested duck genome reveals clues to genetic compensation and crest cushion formation

Chang, G.; Yuan, X.; Guo, Q.; Bai, H.; Cao, X.; Liiu, M.; Wang, Z.; Li, B.; Wang, S.; Jiang, Y.; Wang, Z.; Zhang, Y.; Xu, Q.; Song, Q.; Pan, R.; Zheng, S.; Qiu, L.; Gu, T.; Wu, X.; Bi, Y.; Cao, Z.; Zhang, Y.; Chen, Y.; Li, H.; Liu, J.-F.; Dai, W.; Chen, G.

10.1101/2021.07.25.452189 — genomics — Posted on 2021-07-26

789 N-VEGF, a proteolytic product of the long isoform of VEGF-A, L-VEGF, shuttles to the nucleus to activate cellular stress survival circuits

Katsman, M.; Azriel, A.; Horev, G.; Levi, B.-Z.

10.1101/2021.07.25.453721 — molecular biology — Posted on 2021-07-26

790 Persistence of SARS CoV-2 S1 Protein in CD16+ Monocytes in Post-Acute Sequelae of COVID-19 (PASC) Up to 15 Months Post-Infection

Patterson, B.; Francisco, E. B.; Yogendra, R.; Long, E.; Pise, A.; Rodrigues, H.; Hall, E.; Herrera, M.; Parikh, P.; Guevara-Coto, J.; Triche, T.; Scott, P.; Hekmati, S.; Maglinte, D.; Chang, X.; Rodriguez, R.; Mora, J.

10.1101/2021.06.25.449905 — immunology — Posted on 2021-07-26

791 The dual function monoclonal antibodies VIR-7831 and VIR-7832 demonstrate potent in vitro and in vivo activity against SARS-CoV-2

Cathcart, A. L.; Havenar-Daughton, C.; Lempp, F. A.; Ma, D.; Schmid, M.; Agostini, M. L.; Guarino, B.; Di iulio, J.; Rosen, L.; Tucker, H.; Dillen, J.; Subramanian, S.; Sloan, B.; Bianchi, S.; Wojcechowskyj, J.; Zhou, J.; Kaiser, H.; Chase, A.; Lauron, E.; Montiel-Ruiz, M.; Spreafico, R.; Noack, J.; Czudnochowski, N.; Sahakyan, A.; Pinto, D.; Saliba, C.; Delotta, E.; Park, A.; Cameroni, E.; Ledoux, S.; Werts, A.; Colas, C.; Soriaga, L.; Telenti, A.; Purcell, L. A.; Hwang, S.; Snell, G.; Virgin, H. W.; Corti, D.; Hebner, C. M.

10.1101/2021.03.09.434607 — immunology — Posted on 2021-07-26

792 CD8+ T cell signature in acute SARS-CoV-2 infection identifies memory precursors

Adamo, S.; Michler, J.; Zurbuchen, Y.; Cervia, C.; Taeschler, P.; Raeber, M. E.; Baghai Sain, S.; Nilsson, J.; Moor, A.; Boyman, O.

10.1101/2021.07.22.453029 — immunology — Posted on 2021-07-26

793 Reward-dependent selection of feedback gains impacts rapid motor decisions

De Comite, A.; Crevecoeur, F.; Lefevre, P.

10.1101/2021.07.25.453678 — neuroscience — Posted on 2021-07-26

794 Software for Non-Parametric Image Registration of 2-Photon Imaging Data

Flotho, P.; Nomura, S.; Kuhn, B.; Strauss, D. J.

10.1101/2021.07.25.453381 — neuroscience — Posted on 2021-07-26

795 IQD1 involvement in hormonal signaling and general defense responses against Botrytis cinerea

Barda, O.; Levy, M.

10.1101/2021.07.25.453677 — plant biology — Posted on 2021-07-26

796 Supra-physiological levels of gibberellins/DELLAs modify the root cell size/number and the root architecture in root tips of A. thaliana seedlings. Connections to the root hair patterning and abundance

McCarthy-Suarez, I.

10.1101/2021.07.25.453699 — plant biology — Posted on 2021-07-26

797 Oncogenic c-Myc induces replication stress by increasing cohesins chromatin occupancy

Peripolli, S.; Singh, T.; Patel, H.; Meneguello, L.; Kiso, K.; Thorpe, P. H.; Bertoli, C.; de Bruin, R. A. M.

10.1101/2021.07.25.453647 — cancer biology — Posted on 2021-07-26

798 Role of non-specific interactions in the phase-separation and maturation of macromolecules

Krishnan, R.; Ranganathan, S.; Maji, S. K.; Padinhateeri, R.

10.1101/2021.07.25.453674 — biophysics — Posted on 2021-07-26

799 Modelling time evolution of in blood alcohol concentration

Gelabert, A. O.

10.1101/2021.07.25.452934 — biophysics — Posted on 2021-07-26

800 MetaBinner: a high-performance and stand-alone ensemble binning method to recover individual genomes from complex microbial communities

Wang, Z.; Huang, P.; You, R.; Sun, F.; Zhu, S.

10.1101/2021.07.25.453671 — bioinformatics — Posted on 2021-07-26

801 Artificial Intelligence Resolves Kinetic Pathways of Magnesium Binding to RNA

Neumann, J.; Schwierz, N.

10.1101/2021.07.25.453696 — bioinformatics — Posted on 2021-07-26

802 SegmA: Residue Segmentation of cryo-EM density maps

Wolfson, H. J.; Rozanov, M.

10.1101/2021.07.25.453685 — bioinformatics — Posted on 2021-07-26

803 Driving Native-like Zonal Enthesis Formation in Engineered Ligaments Using Mechanical Boundary Conditions and β-Tricalcium Phosphate

Brown, M. E.; Puetzer, J. L.

10.1101/2021.07.24.453656 — bioengineering — Posted on 2021-07-26

804 Habituation, task solving and memorization may facilitate biological invasions: the Starling example

Rodriguez, A.; Hausberger, M.; Clergeau, P.; Henri, L.

10.1101/2021.07.24.453664 — animal behavior and cognition — Posted on 2021-07-26

805 SOCIAL INFORMATION AND BIOLOGICAL INVASIONS: CHORUS SONGS ARE MORE ATTRACTIVE TO EUROPEAN STARLINGS IN MORE RECENTLY ESTABLISHED POPULATIONS.

Rodriguez, A.; Hausberger, M.; Henri, L.; Clergeau, P.

10.1101/2021.07.24.453665 — animal behavior and cognition — Posted on 2021-07-26

806 Genome Profiling of SARS-CoV-2 in Indonesia, ASEAN and the Neighbouring East Asian Countries: Features, Challenges and Achievements

Cahyani, I.; Putro, E. W.; Ridwanuloh, A. M.; Wibowo, S.; Hariyatun, H.; Syahputra, G.; Akbariani, G.; Utomo, A. R.; Ilyas, M.; Loose, M. W.; Kusharyoto, W.; Indonesian SARS-CoV-2 Genomics Surveillance Network, ; Susanti, S.

10.1101/2021.07.06.451270 — genomics — Posted on 2021-07-26

807 Identification of a divergent basal body assembly protein involved in land plant spermatogenesis

Koshimizu, S.; Minamino, N.; Nishiyama, T.; Yoro, E.; Ebine, K.; sakakibara, k.; Ueda, T.; Yano, K.

10.1101/2021.07.25.453666 — evolutionary biology — Posted on 2021-07-26

808 Bats host the most virulent--but not the most dangerous--zoonotic viruses

Guth, S.; Mollentze, N.; Renault, K.; Streicker, D.; Visher, E.; Boots, M.; Brook, C. E.

10.1101/2021.07.25.453574 — ecology — Posted on 2021-07-26

809 Specialized subsets of innate-like T cells and dendritic cells protect from lethal pneumococcal infection in the lung

Murray, M. P.; Crosby, C. M.; Marcovecchio, P.; Hartmann, N.; Chandra, S.; Zhao, M.; Khurana, A.; Zahner, S. P.; Clausen, B. E.; Coleman, F. T.; Mizgerd, J. P.; Mikulski, Z.; Kronenberg, M.

10.1101/2021.07.25.453697 — immunology — Posted on 2021-07-26

810 Heat-inactivated modified vaccinia virus Ankara boosts Th1-biased cellular and humoral immune responses as a vaccine adjuvant by activating the STING-mediated cytosolic DNA-sensing pathway

Yang, N.; Garzia, A.; Meyer, C.; Tuschl, T.; Merghoub, T.; Wolchok, J.; Deng, L.

10.1101/2021.07.24.453449 — immunology — Posted on 2021-07-26

811 Global, Low Amplitude Cortical State Predicts Response Outcomes in a Selective Detection Task

Marrero, K.; Aruljothi, K.; Zareian, B.; Gao, C.; Zhang, Z.; Zagha, E.

10.1101/2021.07.23.453568 — neuroscience — Posted on 2021-07-26

812 Comprehensive multi-omics single-cell data integration reveals greater heterogeneity in the human immune system

Xu, C.; Yang, J.; Kosters, A.; Babcock, B. R.; Qiu, P.; Ghosn, E.

10.1101/2021.07.25.453651 — systems biology — Posted on 2021-07-26

813 Variability of pollen grains quality in oat amphiploids and their parental species

Tomaszewska, P.; KOSINA, R.

10.1101/2021.07.24.453654 — plant biology — Posted on 2021-07-26

814 A Novel Hypothalamic Factor, Neurosecretory Protein GM, Causes Fat Deposition in Chicks

Kato, M.; Iwakoshi-Ukena, E.; Furumitsu, M.; Ukena, K.

10.1101/2021.07.24.453660 — physiology — Posted on 2021-07-26

815 Overexpression of the gene encoding neurosecretory protein GL precursor prevents excessive fat accumulation in the adipose tissue of mice fed a long-term high-fat diet

Fukumura, K.; Narimatsu, Y.; Moriwaki, S.; Iwakoshi-Ukena, E.; Furumitsu, M.; Ukena, K.

10.1101/2021.07.25.453688 — physiology — Posted on 2021-07-26

816 Cytotoxic Effect of Silver Ions in Combination with Peanut's leaf extract on Cells

Jung, Y.

10.1101/2021.07.24.453619 — pharmacology and toxicology — Posted on 2021-07-26

817 A General Model for Scaling Basal Metabolic Rate, Glomerular Filtration Rate and Drug Clearance from Birth to Adulthood

Hu, T.-M.

10.1101/2021.07.25.453668 — pharmacology and toxicology — Posted on 2021-07-26

818 A Combined Spectroscopic and Molecular Modeling Study on Structure-Function-Dynamics under Chemical Modification: Alpha-Chymotrypsin with Formalin Preservative

Biswas, P.; Adhikari, A.; Pal, U.; Mondal, S.; Mukherjee, D.; Ghosh, R.; Saha-Dasgupta, T.; Chowdhury, S. S.; Das, R.; Pal, S. K.

10.1101/2021.07.24.453635 — biophysics — Posted on 2021-07-26

819 Important Docking study of Structure of Plasmodium falciparum thioredoxin reductase-thioredoxin complex: the case of potent drug Telatinib, a small molecule angiogenesis inhibitor

Ferrari, I. V.

10.1101/2021.07.24.453649 — bioinformatics — Posted on 2021-07-26

820 Population colonization history influences behavioral responses of European starlings in personality tests

Rodriguez, A.; Hausberger, M.; Le Quilliec, P.; Henri, L.; Clergeau, P.

10.1101/2021.07.24.453662 — animal behavior and cognition — Posted on 2021-07-26

821 Leveraging gene co-regulation to identify gene sets enriched for disease heritability

Siewert-Rocks, K. M.; Kim, S. S.; Yao, D.; Shi, H.; Price, A. L.

10.1101/2021.07.22.453442 — genetics — Posted on 2021-07-26

822 The combined toxicity test of polyester and tetra ethylene glycol on Daphnia magna

Jung, Y.

10.1101/2021.07.24.453624 — ecology — Posted on 2021-07-26

823 Disentangling key species interactions in diverse and heterogeneous communities: A Bayesian sparse modeling approach

Weiss-Lehman, C.; Werner, C. M.; Bowler, C. H.; Hallett, L. M.; Mayfield, M. M.; Godoy, O.; Aoyama, L.; Barabas, g.; Chu, C.; Ladouceur, E.; Larios, L.; Shoemaker, L. G.

10.1101/2021.07.23.453227 — ecology — Posted on 2021-07-26

824 High consistency of trophic niches in soil microarthropod species (Oribatida, Acari) across soil depth and forest type

Lu, J.-Z.; Cordes, P. H.; Maraun, M.; Scheu, S.

10.1101/2021.07.24.453652 — ecology — Posted on 2021-07-26

825 Whole body regeneration deploys a rewired embryonic gene regulatory network logic

Warner, J. F.; Johnston, H.; Amiel, A. R.; Nedoncelle, K.; Carvalho, J. E.; Röttinger, E.

10.1101/658930 — developmental biology — Posted on 2021-07-26

826 Trial-wise exposure to visual appetitive cues increases physiological arousal but not temporal discounting.

Knauth, K.; Peters, J.

10.1101/2021.07.24.452477 — neuroscience — Posted on 2021-07-26

827 Emotional states as distinct configurations of functional brain networks

Dan, R.; Weinstock, M.; Goelman, G.

10.1101/2021.07.23.453552 — neuroscience — Posted on 2021-07-26

828 Crowding-induced phase separation of nuclear transport receptors in FG nucleoporin assemblies

Davis, L. K.; Ford, I. J.; Hoogenboom, B. W.

10.1101/2021.07.24.453634 — biophysics — Posted on 2021-07-26

829 AlphaPept, a modern and open framework for MS-based proteomics

Strauss, M. T.; Bludau, I.; Zeng, W.-F.; Voytik, E.; Ammar, C.; Schessner, J.; Ilango, R.; Gill, M.; Meier, F.; Willems, S.; Mann, M.

10.1101/2021.07.23.453379 — bioinformatics — Posted on 2021-07-26

830 PatchPerPixMatch for Automated 3d Search of Neuronal Morphologies in Light Microscopy

Mais, L.; Hirsch, P.; Managan, C.; Wang, K.; Rokicki, K.; Svirskas, R. R.; Dickson, B. J.; Korff, W.; Rubin, G. M.; Ihrke, G.; Meissner, G. W.; Kainmueller, D.

10.1101/2021.07.23.453511 — bioinformatics — Posted on 2021-07-26

831 PCRMS: a database of predicted cis-regulatory modules and constituent transcription factor binding sites in genomes

Ni, P.; Su, Z.

10.1101/2021.07.23.453290 — bioinformatics — Posted on 2021-07-26

832 Generalizing Bayesian phylogenetics to infer shared evolutionary events

Oaks, J. R.; Wood, P. L.

10.1101/2021.07.23.453597 — evolutionary biology — Posted on 2021-07-26

833 A network-based approach reveals the dysregulated transcriptional regulation in non-alcohol fatty liver disease

Yang, H.; Arif, M.; Yuan, M.; Li, X.; Shong, K.; Turkez, H.; Nielsen, J.; Uhlen, M.; Boren, J.; Zhang, C.; Mardinoglu, A.

10.1101/2021.07.24.453650 — systems biology — Posted on 2021-07-26

834 Functional metabolic phenotyping of human pancreatic ductal adenocarcinoma

Heid, I.; Karakaya, S.; Muench, C.; Lueong, S. S.; Winkelkotte, A. M.; Liffers, S. T.; Godfrey, L.; Cheung, P. F.; Savvatakis, K.; Topping, G. J.; Englert, F.; Kritzner, L.; Grashei, M.; Kunzke, T.; Sun, N.; Walch, A.; Tannapfel, A.; Viebahn, R.; Wolters, H.; Uhl, W.; Vangala, D.; Markus-Smeets, E.; Aarntzen, E. H. J. G.; Rauh, D.; Hoheisel, J.; Hellerschmied, D.; Hahn, S.; Schilling, F.; Braren, R.; Trajkovic-Arsic, M.; Siveke, J. T.

10.1101/2021.07.23.452145 — cancer biology — Posted on 2021-07-26

835 Epithelial-mesenchymal plasticity determines estrogen receptor positive (ER+) breast cancer dormancy and reacquisition of an epithelial state drives awakening

Patrik, A.; Yueyun, Z.; Stibolt, C.; Sendurai, M.; Sflomos, G.; Brisken, C.

10.1101/2021.07.22.453458 — cancer biology — Posted on 2021-07-26

836 Segmenting biological specimens from photos to understand the evolution of UV plumage in passerine birds

He, Y.; Cooney, C. R.; Varley, Z. K.; Nouri, L. O.; Moody, C. J. A.; Jardine, M. D.; Maddock, S.; Thomas, G. H.

10.1101/2021.07.22.453339 — evolutionary biology — Posted on 2021-07-26

837 Tumour Suppressor Parafibromin/Hyrax Governs Cell Polarity and Centrosome Assembly in Neural Stem Cells

Deng, Q.; Wang, C.; Koe, C. T.; Heinen, J. P.; Tan, Y. S.; Li, S.; GONZALEZ, C.; Sung, W.-K.; Wang, H.

10.1101/2021.07.06.451232 — developmental biology — Posted on 2021-07-26

838 A putative erm gene is present in ΔermB Clostridioides difficile isolates showing high levels of resistance to clindamycin

Ramirez Hernandez, V.; Ramirez Vargas, G.

10.1101/2020.11.20.391128 — microbiology — Posted on 2021-07-26

839 A Positive Correlation between Bacterial GC Content and Growth Temperature

Hu, E.-Z.; Lan, X.-R.; Liu, Z.-L.; Gao, J.; Niu, D.-K.

10.1101/2021.04.27.441598 — genomics — Posted on 2021-07-26

840 Antithrombin glycoforms from type II antithrombin deficient patients selectively adsorb onto the surface of plasma extracellular vesicles

Radeghieri, A.; Alacqua, S.; Zendrini, A.; Previcini, V.; Todaro, F.; Martini, G.; Ricotta, D.; Bergese, P.

10.1101/2021.07.16.452649 — biochemistry — Posted on 2021-07-26

841 High-resolution simulations of chromatin folding at genomic rearrangements in malignant B-cells provide mechanistic insights on proto-oncogene deregulation

Rico, D.; Kent, D.; Mikulasova, A.; Karataraki, N.; Berlinguer-Palmini, R.; Walker, B. A.; Javierre, B. M.; Russell, L. J.; Brackley, C. A.

10.1101/2021.03.12.434963 — genomics — Posted on 2021-07-26

842 Maturation of distinct neural components of the cognitive control network support early development of inhibitory control

Berger, P.; Friederici, A. D.; Grosse Wiesmann, C.

10.1101/2021.07.02.450852 — neuroscience — Posted on 2021-07-26

843 Bamboos flower after the return of almost the same sun-moon phasing as at seedling emergence

Clerget, B.

10.1101/2021.06.11.448081 — plant biology — Posted on 2021-07-26

844 Fully Convolutional Networks for pathophysiological Intracranial Pressure waveform classification

Vrabie, O.; Faltermeier, R.; Schmidt, N. O.; Brawanski, A.; Lang, E. W.

10.1101/2020.11.17.381517 — physiology — Posted on 2021-07-26

845 A prioritized and validated resource of mitochondrial proteins in Plasmodium identifies leads to unique biology

van Esveld, S. L.; Meerstein-Kessel, L.; Boshoven, C.; Baaij, J.; Barylyuk, K.; Coolen, J.; van Strien, J.; Duim, R. A. J.; Dutilh, B. E.; Garza, D. R.; Letterie, M.; Proellochs, N. I.; de Ridder, M. N.; Venkatasubramanian, P. B.; de Vries, L. E.; Waller, R. F.; Kooij, T. W. A.; Huynen, M. A.

10.1101/2021.01.22.427784 — bioinformatics — Posted on 2021-07-26

846 A yeast lysosomal biogenesis map uncovers the cargo spectrum of lysosomal protein targeting pathways

Eising, S.; Esch, B. M.; Waelte, M.; Vargas Duarte, P.; Walter, S.; Ungermann, C.; Bohnert, M.; Froehlich, F.

10.1101/2021.07.24.453616 — cell biology — Posted on 2021-07-26

847 The dual nature of bacteriophage: growth-dependent predation and generalised transduction of antimicrobial resistance

Leclerc, Q. J.; Wildfire, J.; Gupta, A.; Lindsay, J. A.; Knight, G. M.

10.1101/2021.07.24.453184 — microbiology — Posted on 2021-07-26

848 BAI-Net: Individualized Human Cerebral Cartography using Graph Convolutional Network

Ma, L.; Zhang, Y.; Zhang, H.; Cheng, L.; Zhuo, J.; Shi, W.; Lu, Y.; Li, W.; Wang, J.; Yang, Z.; Fan, L.; Jiang, T.

10.1101/2021.07.15.452577 — neuroscience — Posted on 2021-07-26

849 A multi-gene region targeted capture approach to detect plant DNA in environmental samples: A case study from coastal environments

Foster, N.; Van Dijk, K.-j.; Biffin, E.; Young, J.; Thomson, V. A.; Gillanders, B.; Jones, A.; Waycott, M.

10.1101/2021.07.03.450983 — molecular biology — Posted on 2021-07-26

850 Value Certainty in Drift-Diffusion Models of Preferential Choice

Lee, D.; Usher, M.

10.1101/2020.08.22.262725 — neuroscience — Posted on 2021-07-26

851 Beneficial effects of the AFO-202 and N-163 strains of Aureobasidium pullulans produced 1,3-1,6 beta glucans on non-esterified fatty acid levels in obese diabetic KKAy mice: A comparative study

Ikewaki, N.; Onaka, T.; Ikeue, Y.; Nagataki, M.; Kurosawa, G.; Dedeepiya, V. D.; Rajmohan, M.; Vaddi, S.; Senthilkumar, R.; Preethy, S.; Abraham, S. J.

10.1101/2021.07.22.453362 — pharmacology and toxicology — Posted on 2021-07-26

852 Trophic transfer of microplastics enhances tissue accumulation of chemical additives in fish

Hasegawa, T.; Mizukawa, K.; Yeo, G. B.; Sekioka, T.; Takada, H.; Nakaoka, M.

10.1101/2021.03.09.434685 — pharmacology and toxicology — Posted on 2021-07-26

853 Identifying cell-state associated alternative splicing events and their co-regulation

Buen Abad Najar, C. F.; Burra, P.; Yosef, N.; Lareau, L. F.

10.1101/2021.07.23.453605 — genomics — Posted on 2021-07-25

854 Disentangling niche theory and beta diversity change

Godsoe, W.; Bellingham, P. J.; Moltchanova, E.

10.1101/2021.07.05.451214 — ecology — Posted on 2021-07-25

855 The Series of a Four-node Motif and Coherent Type-1 Feed-forward Loop can Provide Sensitive Detection over Arbitrary Range of Input Signal, thereby Explain Weber's Law in Higher-Order Sensory Processes, and Compute Logarithm

Wadhwa, D.

10.1101/2020.04.08.032193 — systems biology — Posted on 2021-07-25

856 Energetics but not development is impacted in coral embryos exposed to ocean acidification

Chille, E. E.; Strand, E. L.; Scucchia, F.; Schmidt, V.; Neder, M.; Sherman, M. O.; Mass, T.; Putnam, H. M.

10.1101/2021.07.19.452948 — physiology — Posted on 2021-07-25

857 A combined bioinformatics and LC-MS based approach for the development and benchmarking of a comprehensive database for CNS proteins in Lymnaea stagnalis

Wooller, S.; Anagnostopoulou, A.; Kuropka, B.; Crossley, M.; Benjamin, P. R.; Pearl, F.; Kemenes, I.; Kemenes, G.; Eravci, M.

10.1101/2021.05.03.442491 — bioinformatics — Posted on 2021-07-25

858 Modelling Human Gait using a Nonlinear Differential Equation

Schmalz, J.; Paul, D.; Shorter, K.; Schmalz, X.; Cooper, M.; Murphy, A.

10.1101/2021.03.16.435713 — bioengineering — Posted on 2021-07-25

859 The evolutionary origins of primate scleral coloration

Mearing, A. S.; Burkart, J. M.; Dunn, J.; Street, S. E.; Koops, K.

10.1101/2021.07.25.453695 — animal behavior and cognition — Posted on 2021-07-25

860 Mathematical constraints on FST: multiallelic markers in arbitrarily many populations

Alcala, N.; Rosenberg, N. A.

10.1101/2021.07.23.453474 — genetics — Posted on 2021-07-25

861 Sgs1BLM independent role of Dna2DNA2 nuclease at DNA double strand break is inhibited by Nej1XLF

Mojumdar, A.; Adam, N.; Cobb, J. A.

10.1101/2021.04.10.439283 — genetics — Posted on 2021-07-25

862 The cold-drought tolerance trade-off in temperate woody plants constrains range size, but not range filling

Puglielli, G.; Tordoni, E.; Humphreys, A.; Kalwij, J. M.; Hutchings, M. J.; Laanisto, L.

10.1101/2021.07.24.453622 — ecology — Posted on 2021-07-25

863 Epigenetic reprogramming ameliorates type 1 diabetes by decreasing the generation of Th1 and Th17 subsets and restoring self-tolerance in CD4+ T cells

Patel, V.; Jayaraman, A.; Jayaraman, S.

10.1101/2021.07.24.453657 — immunology — Posted on 2021-07-25

864 Necroptosis increases with age in the brain and contributes to age-related neuroinflammation

Thadathil, N.; Nicklas, E.; Jazir, S.; Lewis, T. L.; Richardson, A.; Deepa, S. S.

10.1101/2021.07.23.453580 — neuroscience — Posted on 2021-07-25

865 Transcriptomic Analysis of Human Sensory Neurons in Painful Diabetic Neuropathy Reveals Inflammation and Neuronal Loss

Hall, B.; Macdonald, E.; Cassidy, M.; Yun, S.; Sapio, M.; Ray, P.; Doty, M.; Nara, P.; Burton, M. D.; Shiers, S.; Ray-Chaudhury, A.; Mannes, A. J.; Price, T. J.; Iadarola, M. J.; Kulkarni, A. B.

10.1101/2021.07.23.453576 — neuroscience — Posted on 2021-07-25

866 Epigenetic Malleability at Core Promoter Regulates Tobacco PR-1a Expression after Salicylic Acid Treatment

Lodhi, N.; Singh, M.; Srivastva, R.; Sawant, S. V.; Tuli, R.

10.1101/2021.07.24.453639 — plant biology — Posted on 2021-07-25

867 Tropomyosin isoforms segregate into distinct clusters on single actin filaments

Obeidy, P.; Sobey, T.; Nicovich, P. R.; Coster, A. C. F.; Pandzic, E.

10.1101/2021.07.23.453476 — biophysics — Posted on 2021-07-25

868 Reducing indoor particle exposure using mobile air purifiers - experimental and numerical analysis

Tobisch, A.; Springsklee, L.; Schaefer, L.-F.; Sussmann, N.; Lehmann, M. J.; Weis, F.; Zoellner, R.; Niessner, J.

10.1101/2021.07.23.453308 — biophysics — Posted on 2021-07-25

869 A community-based approach to image analysis of cells, tissues and tumors

CSBC/PS-ON Image Analysis Working Group, ; Vizcarra, J. C.; Burlingame, E. A.; Hug, C. B.; Goltsev, Y.; White, B. S.; Tyson, D. R.; Sokolov, A.

10.1101/2021.07.22.451363 — bioinformatics — Posted on 2021-07-25

870 Capturing variation in metagenomic assembly graphs with MetaCortex

Martin, S.; Ayling, M.; Patrono, L.; Caccamo, M.; Murcia, P.; Leggett, R. M.

10.1101/2021.07.23.453484 — bioinformatics — Posted on 2021-07-25

871 Green self-immolative polymer: molecular antenna to collect and propagate the signal for zymogen activation

Montasell, M. C.; Monge, P.; Carmali, S.; Mesquita, L.; Andersen, D.; Lovschall, K.; Sogaard, A.; Kristensen, M.; Pütz, J.; Zelikin, A. N.

10.1101/2021.07.25.453687 — biochemistry — Posted on 2021-07-25

872 Functional asymmetry and chemical reactivity of CsoR family persulfide sensors

Fakhoury, J.; Zhang, Y.; Edmonds, K. A.; Bringas, M.; Luebke, J.; Gonzalez-Gutierrez, G.; Capdevila, D. A.; Giedroc, D. P.

10.1101/2021.07.25.453692 — biochemistry — Posted on 2021-07-25

873 Unraveling the regulatory role of miRNAs responsible for proanthocyanidin biosynthesis in the underutilized legume Psophocarpus tetragonolobus (L.) DC.

Nayak, S. P.; Prasad, P.; Singh, V.; Tripathi, A. M.; Bag, S. K.; Mohanty, C. S.

10.1101/2021.07.24.453638 — genomics — Posted on 2021-07-25

874 Low dose/dose rate γ irradiation protects Drosophila melanogaster chromosomes from double strand breaks and telomere fusions by modulating the expression of Loquacious.

Porrazzo, A.; Cipressa, F.; De Gregorio, A.; De Pitta, C.; Sales, G.; Morciano, P.; Esposito, G.; Tabocchini, A.; Cenci, G.

10.1101/2021.07.23.453515 — genetics — Posted on 2021-07-25

875 Evaluating 87Sr/86Sr isotope ratios and Sr mass fractions in otoliths of different European freshwater fish species as fishery management tool in an Alpine foreland with limited geological variability

Zitek, A.; Oehm, J.; Schober, M.; Tchaikovsky, A.; Irrgeher, J.; Retzmann, A.; Thalinger, B.; Traugott, M.; Prohaska, T.

10.1101/2021.07.23.453494 — ecology — Posted on 2021-07-25

876 Large positive ecological changes of small urban greening actions

Mata, L.; Hahs, A. K.; Palma, E.; Backstrom, A.; King, T.; Olson, A. R.; Renowden, C.; Smith, T. R.; Vogel, B.

10.1101/2021.07.23.453468 — ecology — Posted on 2021-07-25

877 Evolution of a chordate-specific mechanism for myoblast fusion

Zhang, H.; Shang, R.; Kim, K.; Zheng, W.; Johnson, C. J.; Sun, L.; Niu, X.; Liu, L.; Uyeno, T. A.; Zhou, J.; Liu, L.; Pei, J.; Fissette, S. D.; Green, S. A.; Samudra, S. P.; Wen, J.; Zhang, J.; Eggenschwiler, J.; Menke, D.; Bronner, M. E.; Grishin, N. V.; Li, W.; Ye, K.; Zhang, Y.; Stolfi, A.; Bi, P.

10.1101/2021.07.24.453587 — developmental biology — Posted on 2021-07-25

878 Assessing donor-to-donor variability in human intestinal organoid cultures

Mohammadi, S.; Morell-Perez, C.; Wright, C. W.; Wyche, T. P.; White, C. H.; Sana, T. R.; Lieberman, L. A.

10.1101/2021.07.23.453590 — developmental biology — Posted on 2021-07-25

879 A yeast lysosomal biogenesis map uncovers the cargo spectrum of lysosomal protein targeting pathways

Eising, S.; Esch, B. M.; Waelte, M.; Walter, S.; Ungermann, C.; Bohnert, M.; Froehlich, F.

10.1101/2021.07.24.453616 — cell biology — Posted on 2021-07-25

880 Eukaryotic genomes from a global metagenomic dataset illuminate trophic modes and biogeography of ocean plankton

Alexander, H.; Hu, S. K.; Krinos, A. I.; Pachiadaki, M.; Tully, B. J.; Neely, C. J.; Reiter, T.

10.1101/2021.07.25.453713 — microbiology — Posted on 2021-07-25

881 Monitoring spore dispersal and early infections of Diplocarpon coronariae causing apple blotch using selected spore traps and a new qPCR method

Boutry, C.; Bohr, A.; Buchleither, S.; Ludwig, M.; Oberhänsli, T.; Tamm, L.; Schärer, H.-J.; Flury, P. C.

10.1101/2021.07.25.453640 — microbiology — Posted on 2021-07-25

882 A distinct CD115- erythro-myeloid precursor present at the maternal-embryonic interface and in the bone marrow of adult mice

Tikoo, S.; Jain, R.; Martinez, B.; Song, R.; Wielscher, M.; Rizzetto, S.; Shaw, L. E.; Mitchell, A. J.; Torres-Pacheco, M. E.; Luciani, F.; Farlik, M.; Wong, J.; Jung, S.; Fraser, S. T.; Weninger, W.

10.1101/2021.07.24.453629 — immunology — Posted on 2021-07-25

883 Neuron-Glia Signaling Regulates the Onset of the Antidepressant Response

Yao, V.; Aly, A.; Kalik, S.; Gresack, J.; Wang, W.; Handler, A.; Schaefer, A.; Troyanskaya, O.; Greengard, P.; Chottekalapanda, R. U.

10.1101/2021.07.23.453443 — neuroscience — Posted on 2021-07-25

884 A distributed dopamine-gated circuit underpins reproductive state-dependent behavior in Drosophila females

Boehm, A. C.; Friedrich, A. B.; Bandow, P.; Siju, K. P.; Hunt, S.; Claussen, J.; Link, M.-H.; Hofmann, T. F.; Dawid, C.; Grunwald Kadow, I. C.

10.1101/2021.07.24.453623 — neuroscience — Posted on 2021-07-25

885 PiRATeMC: A highly flexible, scalable, and affordable system for obtaining high quality video recordings for behavioral neuroscience.

Centanni, S. W.; Smith, A. C.

10.1101/2021.07.23.453577 — neuroscience — Posted on 2021-07-25

886 Lateral habenula M2 muscarinic receptor control of neuronal activity and cocaine seeking behavior

Wolfe, C. I. C.; Hwang, E.-K.; Zapata, A.; Hoffman, A. F.; Lupica, C. R.

10.1101/2021.07.24.453572 — neuroscience — Posted on 2021-07-25

887 Mechanisms of phosphatidylserine influence on viral production: a computational model of Ebola virus matrix protein assembly

Liu, X.; Pappas, E. J.; Husby, M. L.; Stahelin, R. V.; Pienaar, E.

10.1101/2021.07.22.453424 — systems biology — Posted on 2021-07-25

888 Transmembrane signalling by a bionic receptor: biological input and output, chemical mechanism of signal transduction

Lovschall, K. B.; Monge, P.; Nielsen, L.; Stevanovic, S.; Walther, R.; Zelikin, A. N.

10.1101/2021.07.25.453684 — synthetic biology — Posted on 2021-07-25

889 Pyridoxal 5'-phosphate supplementation modulates the heterologous expression and activity of a PLP dependent model protein in E.coli

SAXENA, V. K.; Vedamurthy, G. V.; Singh, R.

10.1101/2021.07.25.453669 — biochemistry — Posted on 2021-07-25

890 Estimation of Average Blood Glucose Values Based on Fructosamine Values

de Oliveira Andrade, L. J.; Bittencourt, A. M. V.; Moreno de Brito, L. F.; Matos de Oliveira, L.; Matos de Oliveira, G. C.

10.1101/2021.07.25.453711 — biochemistry — Posted on 2021-07-25

891 How alginate lyase produces quasi-monodisperse oligosaccharides: a normal mode analysis-based docking and molecular dynamics simulation study

Xu, H.; Gao, Q.; Ming, D.

10.1101/2021.07.25.452152 — biochemistry — Posted on 2021-07-25

892 The ribose methylation enzyme FTSJ1 has a conserved role in neuron morphology and learning performance

Dimitrova, D. G.; Brazane, M.; Pigeon, J.; Paolantoni, C.; Tao, Y.; Marchand, V.; Da Silva, B.; Schaefer, E.; Angelova, M. T.; Stark, Z.; Delatycki, M.; Dudding, T.; Gecz, J.; Placais, P.-Y.; Teysset, L.; Preat, T.; Piton, A.; Hassan, B. A.; Roignant, J.-Y.; Motorin, Y.; Carre, C.

10.1101/2021.02.06.430044 — genetics — Posted on 2021-07-25

893 Transcription and splicing dynamics during early Drosophila development

Prudencio, P.; Savisaar, R.; Rebelo, K.; Martinho, R. G.; Carmo-Fonseca, M.

10.1101/2020.11.05.367888 — molecular biology — Posted on 2021-07-25

894 Adapted protocol for Saccharibacteria co-cultivation: two new members join the club of Candidate Phyla radiation

Ibrahim, A.; Maatouk, M.; Rajaonison, A.; Zgheib, R.; Haddad, G.; Bou Khalil, J. Y.; Raoult, D.; Bittar, F.

10.1101/2021.07.23.453610 — microbiology — Posted on 2021-07-25

895 Social Reactivation of Fear Engrams Enhances Memory Recall

Finkelstein, A. B.; Leblanc, H.; Cole, R.; Gallerani, T.; Vieira, A.; Zaki, Y.; Ramirez, S.

10.1101/2021.01.07.425728 — neuroscience — Posted on 2021-07-25

896 The olfactory organ is a unique site for resident neutrophils in the brain

Whitlock, K. E.; Palominos, M. F.; Candia, D.; Torres-Paz, J.

10.1101/2021.07.22.453396 — neuroscience — Posted on 2021-07-25

897 Intrinsic water use efficiency depends on stomatal aperture rather than stomatal density in C3 and C4 grasses grown at glacial CO2 and low light

Israel, W. K.; Watson-Lazowski, A.; Chen, Z.-H.; Ghannoum, O.

10.1101/2021.07.22.453465 — plant biology — Posted on 2021-07-25

898 Chemically-induced epimutagenesis allows bypassing reproductive barriers in hybrid seeds

Borges, F.; Huc, J.; Dziasek, K.; Pachamuthu, K.; Woh, T.; Köhler, C.

10.1101/2021.07.23.453551 — plant biology — Posted on 2021-07-25

899 Genomic events shaping epithelial-to-mesenchymal trajectories in cancer

Malagoli Tagliazucchi, G.; Secrier, M.

10.1101/2021.07.23.453584 — cancer biology — Posted on 2021-07-25

900 PTEN mutant NSCLC require ATM to suppress pro-apoptotic signalling and evade radiotherapy

Fischer, T.; Hartmann, O.; Reissland, M.; Prieto-Garcia, C.; Klann, K.; Schuelein-Voelk, C.; Polat, B.; Gebhard-Hartmann, E.; Rosenfeldt, M.; Muench, C.; Flentje, M.; Diefenbacher, M. E.

10.1101/2021.07.24.453632 — cancer biology — Posted on 2021-07-25

901 A protocol for good quality genomic DNA isolation from formalin-fixed paraffin-embedded tissues without using commercial kits

Talukdar, F. R.; Abramovic, I.; Cuenin, C.; Carreira, C.; Gangane, N.; Sincic, N.; Herceg, Z.

10.1101/2021.07.23.452892 — cancer biology — Posted on 2021-07-25

902 In vitro and in vivo analysis of microvesicle-mediated metastasis using a bright, red-shifted bioluminescent reporter protein of extracellular vesicles

Zarea, A. A.; Perez, G. I.; Broadbent, D.; Dolgikh, B.; Bernard, M. P.; Withrow, A.; McGill, A.; Toomajian, V.; Thampy, L. K.; Harkema, J.; Walker, J. R.; Kirkland, T. A.; Bachmann, M. H.; Schmidt, J.; Kanada, M.

10.1101/2021.07.23.453512 — cancer biology — Posted on 2021-07-25

903 Knowledge Graph-based Recommendation Framework Identifies Novel Drivers of Resistance in EGFR mutant Non-small Cell Lung Cancer

Gogleva, A.; Polychronopoulos, D.; Pfeifer, M.; Poroshin, V.; Ughetto, M.; Sidders, B.; Ahdesmaki, M.; McDermott, U.; Papa, E.; Bulusu, K.

10.1101/2021.07.23.453506 — cancer biology — Posted on 2021-07-25

904 Widespread germline genetic heterogeneity of human ribosomal RNA genes

Fan, W.; Eklund, E.; Sherman, R. M.; Liu, H.; Pitts, S.; Ford, B.; NV, R.; Laiho, M.

10.1101/2021.07.21.453267 — bioinformatics — Posted on 2021-07-25

905 Motor Sequences - Separating The Sequence From The Motor. A longitudinal rsfMRI Study

Jaeger, A.-T. P.; Huntenburg, J. M.; Tremblay, S. A.; Schneider, U.; Grahl, S.; Huck, J.; Tardif, C. L.; Villringer, A.; Gauthier, C. J.; Bazin, P.-L.; Steele, C. J.

10.1101/2021.02.09.430495 — neuroscience — Posted on 2021-07-25

906 Strong and opponent contributions of dorsomedial striatal pathways to behavior depends on cognitive demands and task strategy

Bolkan, S.; Stone, I.; Pinto, L.; Ashwood, Z.; Garcia, J.; Herman, A.; Singh, P.; Bandi, A.; Cox, J.; Zimmerman, C.; Cho, J.; Engelhard, B.; Koay, S.; Pillow, J.; Witten, I.

10.1101/2021.07.23.453573 — neuroscience — Posted on 2021-07-25

907 The role of syndapin-2 mediated transcytosis across the blood-brain barrier on amyloid-beta accumulation in the brain

Leite, D. M.; Seifi, M.; Ruiz-Perez, L.; Nguemo, F.; Plomann, M.; Swinny, J. D.; Battaglia, G.

10.1101/2020.07.12.199869 — neuroscience — Posted on 2021-07-25

908 Profiling of human neural crest chemoattractant activity as replacement of fetal bovine serum for in vitro chemotaxis assays

Dolde, X.; Karreman, C.; Wiechers, M.; Schildknecht, S.; Leist, M.

10.1101/2021.07.19.452897 — pharmacology and toxicology — Posted on 2021-07-25

909 Self-organized morphogenesis of a human neural tube in vitro by geometric constraints

Karzbrun, E.; Khankhel, A.; Megale, H.; Glasauer, S.; Wyle, Y.; Britton, G.; Warmflash, A.; Kosik, K. S.; Siggia, E.; Shraiman, B.; Streichan, S. J.

10.1101/2021.07.24.453659 — developmental biology — Posted on 2021-07-25

910 Glutamatergic dysfunction leads to a hyper-dopaminergic phenotype through deficits in short-term habituation: a mechanism for aberrant salience.

Panayi, M. C.; Boerner, T.; Jahans-Price, T.; Huber, A.; Sprengel, R.; Gilmour, G.; Sanderson, D. J.; Harrison, P. J.; Walton, M. E.; Bannerman, D. M.

10.1101/2021.07.23.453593 — neuroscience — Posted on 2021-07-25

911 Mechanosensitivity of nucleocytoplasmic transport

Andreu, I.; Granero, I.; Chahare, N.; Clein, K.; Molina Jordan, M.; Beedle, A. E. M.; Elosegui-Artola, A.; Trepat, X.; Raveh, B.; Roca-Cusachs, P.

10.1101/2021.07.23.453478 — biophysics — Posted on 2021-07-24

912 Toxin breakdown does not preclude the potential for defensive toxin use in a fruit fly

Douglas, T. E.; Beskid, S. G.; Gernand, C. E.; Nirtaut, B. E.; Tamsil, K. E.; Fitch, R. W.; Tarvin, R. D.

10.1101/2021.07.23.453507 — evolutionary biology — Posted on 2021-07-24

913 The desmin mutation R349P increases contractility and fragility of stem cell-generated muscle micro-tissues

Spoerrer, M.; Kah, D.; Gerum, R. C.; Reischl, B.; Huraskin, D.; Dessalles, C. A.; Schneider, W.; Goldmann, W. H.; Herrmann, H.; Thievessen, I.; Clemen, C. S.; Friedrich, O.; Hashemolhosseini, S.; Schroeder, R.; Fabry, B.

10.1101/2021.07.23.453481 — biophysics — Posted on 2021-07-24

914 Individual differences in members of Actinobacteria, Bacteroidetes, and Firmicutes is associated with resistance or vulnerability to addiction-like behaviors in heterogeneous stock rats

Simpson, S.; de Guglielmo, G.; Brennan, M.; Maturin, L.; Peters, G.; Jia, H.; Andrews, S.; Solberg-Woods, L.; Palmer, A.; George, O.

10.1101/2021.07.23.453592 — animal behavior and cognition — Posted on 2021-07-24

915 Trait-trait relationships and functional tradeoffs vary with genome size in prokaryotes

Beier, S.; Werner, J.; Bouvier, T.; Mouquet, N.; Violle, C.

10.1101/2021.07.23.453341 — ecology — Posted on 2021-07-24

916 Regulation of neuronal progenitor delamination by dynein-driven post-Golgi apical transport

Brault, J.-B.; Bardin, S.; Lampic, M.; Carpentieri, J.; Coquand, L.; Penisson, M.; Lachuer, H.; Victoria, G. S.; Baloul, S.; Boncompain, G.; Miserey-Lenkei, S.; Fraisier, V.; Francis, F.; Perez, F.; Goud, B.; Baffet, A. D.

10.1101/2021.07.23.453475 — cell biology — Posted on 2021-07-24

917 Refining the domain architecture model of the replication origin firing factor Treslin/TICRR

Ferreira, P.; Sanchez-Pulido, L.; Marko, A.; Ponting, C. P.; Boos, D.

10.1101/2021.07.24.453613 — molecular biology — Posted on 2021-07-24

918 IFITM3 regulates virus-induced inflammatory cytokine production by titrating Nogo-B orchestration of TLR responses

Clement, M.; Forbester, J. L.; Marsden, M.; Sabberwal, P.; Wellington, D.; Dimonte, S.; Harcourt, K.; Clare, S.; Yin, Z.; Nobre, L.; Antrobus, R.; Jin, B.; Chen, M.; Makvandi-Nejad, S.; Lindborg, J. A.; Strittmatter, S. M.; Weekes, M. P.; Stanton, R. j.; Dong, T.; Humphreys, I.

10.1101/2021.07.23.453513 — immunology — Posted on 2021-07-24

919 A BioBricks toolbox for multiplexed metabolic engineering of central carbon metabolism in the tetracenomycin pathway

Nguyen, J. T.; Riebschleger, K. K.; Brown, K. V.; Gorgijevska, N. M.; Nybo, E.

10.1101/2021.07.23.453519 — synthetic biology — Posted on 2021-07-24

920 Genomic rearrangements have consequences for introgression breeding as revealed by genome assemblies of wild and cultivated lentil species

Ramsay, L.; Koh, C. S.; Kagale, S.; Gao, D.; Kaur, S.; Haile, T.; Gela, T. S.; Chen, L.-A.; Cao, Z.; Konkin, D. J.; Toegelova, H.; Dolezel, J.; Rosen, B. D.; Stonehouse, R.; Humann, J. L.; Main, D.; Coyne, C. J.; McGee, R. J.; Cook, D. R.; Penmetsa, R. V.; Vandenberg, A.; Chan, C.; Banniza, S.; Edwards, D.; Bayer, P. E.; Batley, J.; Udupa, S. M.; Bett, K. E.

10.1101/2021.07.23.453237 — plant biology — Posted on 2021-07-24

921 A ubiquitously expressed UDP-glucosyltransferase, UGT74J1, controls basal salicylic acid levels in rice

Tezuka, D.; Matsuura, H.; Saburi, W.; Mori, H.; Imai, R.

10.1101/2021.07.24.453630 — plant biology — Posted on 2021-07-24

922 Mapping drug-microenvironment-genetic interplay in CLL reveals trisomy 12 as a modulator of microenvironmental signals

Bruch, P.-M.; Giles, H.; Kolb, C.; Herbst, S. A.; Becirovic, T.; Roider, T.; Lu, J.; Scheinost, S.; Wagner, L.; Hüllein, J.; Berest, I.; Kriegsmann, M.; Kriegsmann, K.; Zgorzelski, C.; Dreger, P.; Zaugg, J. B.; Müller-Tidow, C.; Zenz, T.; Huber, W.; Dietrich, S.

10.1101/2021.07.23.453514 — cancer biology — Posted on 2021-07-24

923 An anti-ACVR1 antibody exacerbates heterotopic ossification by fibro/adipogenic progenitors in fibrodysplasia ossificans progressiva mice

Lees-Shepard, J. B.; Stoessel, S. J.; Chandler, J.; Bouchard, K.; Bento, P.; Apuzzo, L. N.; Devarakonda, P. M.; Hunter, J. W.; Goldhamer, D. J.

10.1101/2021.07.23.451471 — developmental biology — Posted on 2021-07-24

924 Blood flow coordinates collective endothelial cell migration during vascular plexus formation and promotes angiogenic sprout regression via vegfr3/flt4

Chen, Y.; Jiang, Z.; Fisher, K. H.; Kim, H. R.; Evans, P. C.; Wilkinson, R. N.

10.1101/2021.07.23.453496 — developmental biology — Posted on 2021-07-24

925 Cell-state specific aggresome formation in fibroblasts is driven by stress-activated MAPK signaling

Morrow, C. S.; Arndt, Z. P.; Peng, B.; Zewdie, E. Y.; Benayoun, B. A.; Moore, D. L.

10.1101/2021.07.23.453501 — cell biology — Posted on 2021-07-24

926 Principles of mRNA targeting via the Arabidopsism6A-binding protein ECT2

Arribas-Hernandez, L.; Rennie, S.; Koester, T.; Porcelli, C.; Lewinski, M.; Staiger, D.; Andersson, R.; Brodersen, P.

10.1101/2021.04.18.440342 — molecular biology — Posted on 2021-07-24

927 Golden Gate Assembly of Aerobic and Anaerobic Microbial Bioreporters

Hinz, A. J.; Stenzler, B. R.; Poulain, A. J.

10.1101/2021.07.23.453609 — molecular biology — Posted on 2021-07-24

928 FTO suppresses STAT3 activation and modulates proinflammatory interferon-stimulated gene expression

McFadden, M. J.; Sacco, M. T.; Murphy, K. A.; Park, M.; Gokhale, N. S.; Somfleth, K. Y.; Horner, S. M. M.

10.1101/2021.07.23.453596 — molecular biology — Posted on 2021-07-24

929 Hundreds of viral families in the healthy infant gut

Shah, S. A.; Deng, L.; Thorsen, J.; Pedersen, A. G.; Dion, M. B.; Castro Mejia, J.; Silins, R.; Romme, F. O.; Sausset, R.; Ndela, E. O.; Hjemso, M. H.; Rasmussen, M. A.; Redgwell, T.; Vestergaard, G. A.; Zhang, Y.; Sorensen, S. J.; Bisgaard, H.; Enault, F.; Stokholm, J.; Moineau, S.; Petit, M.-A.; Nielsen, D. S.

10.1101/2021.07.02.450849 — microbiology — Posted on 2021-07-24

930 The transcription factor Zeb2 drives differentiation of age-associated B cells

Gu, S.; Han, X.; Yao, C.; Ding, H.; Zhang, J.; Hou, G.; Qu, B.; Zhou, H.; Ying, Z.; Ye, Z.; Qian, J.; Guo, Q.; Chen, S.; Vinuesa, C. G.; Dai, D.; Shen, N.

10.1101/2021.07.24.453633 — immunology — Posted on 2021-07-24

931 Structure of long-range direct and indirect spinocerebellar pathways as well as local spinal circuits mediating proprioception.

Pop, I. V.; Espinosa-Becerra, F.; Blevins, C. J.; Okafor, P. C.; Ogujiofor, O.; Goyal, M.; Mona, B.; Landy, M.; Dean, K. M.; Gurumurthy, C. M.; Lai, H. C.

10.1101/2020.08.17.254607 — neuroscience — Posted on 2021-07-24

932 Characterization of glucosyltransferase and glucuronosyltransferase family members reveals how major flavone glycoside accumulate in the root of Scutellaria baicalensis

Pei, T.; Li, T.; Li, X.; Yin, Y.; Cui, M.; Fang, Y.; Liu, J.; Kong, Y.; Xu, P.; Zhao, Q.

10.1101/2021.07.24.453627 — plant biology — Posted on 2021-07-24

933 DNA mismatch and damage detection using a FRET-based assay for monitoring the loading of multiple MutS sliding clamps

Kunetsky, V.; Storozhuk, O.; Brouwer, G.; Laffeber, C.; Dillingham, M. S.; Lebbink, J.; Friedhoff, P.

10.1101/2021.07.23.453479 — biochemistry — Posted on 2021-07-24

934 Sulfated host glycan recognition by carbohydrate sulfatases of the human gut microbiota

Luis, A. S.; Basle, A.; Byrne, D. P.; Wright, G. S.; London, J.; Chunsheng, J.; Karlsson, N.; Hansson, G. C.; Eyers, P. A.; Czjzek, M.; Barbeyron, T.; Yates, E. A.; Martens, E. C.; Cartmell, A.

10.1101/2021.07.23.453482 — biochemistry — Posted on 2021-07-24

935 Malaria parasite evades mosquito immunity by glutaminyl cyclase mediated protein modification

Kolli, S. K.; Molina-Cruz, A.; Araki, T.; Geurten, F. J. A. v.; Ramesar, J.; Chevalley-Maurel, S.; Kroeze, H. J.; Bezemer, S.; de Korne, C.; Withers, R.; Raytselis, N.; El Hebieshy, A. F.; Kim, R. Q.; Child, M.; Kakuta, S.; Hisaeda, H.; Kobayashi, H.; Annoura, T.; Hensbergen, P. J.; Franke-Fayard, B. M.; Barillas-Mury, C.; Scheeren, F. A.; Janse, C. J.

10.1101/2021.07.23.453408 — microbiology — Posted on 2021-07-24

936 The human neuronal receptor NgR1 bridges reovirus capsid proteins to initiate infection

Sutherland, D. M.; Strebl, M.; Koehler, M.; Welsh, O. L.; Yu, X.; Hu, L.; dos Santos Natividade, R.; Knowlton, J. J.; Taylor, G. M.; Moreno, R.; Woerz, P.; Lonergan, Z. L.; Aravamudhan, P.; Guzman-Cardozo, C.; Alsteens, D.; Wang, Z.; Prasad, B.; Stehle, T.; Dermody, T. S.

10.1101/2021.07.23.453469 — microbiology — Posted on 2021-07-24

937 The dual nature of bacteriophage: growth-dependent predation and generalised transduction of antimicrobial resistance

Leclerc, Q. J.; Wildfire, J.; Gupta, A.; Lindsay, J. A.; Knight, G. M.

10.1101/2021.07.24.453184 — microbiology — Posted on 2021-07-24

938 SRS-FISH: High-Throughput Platform Linking Microbiome Function to Identity at the Single Cell Level

Ge, X.; Pereira, F. C.; Mitteregger, M.; Berry, D.; Zhang, M.; Wagner, M.; Cheng, J.-X.

10.1101/2021.07.23.453601 — microbiology — Posted on 2021-07-24

939 Spatial and temporal localization of cell wall associated pili in Enterococcus faecalis

Choo, P. Y.; Wang, C.; VanNieuwenhze, M.; Kline, K.

10.1101/2021.07.23.451969 — microbiology — Posted on 2021-07-24

940 Determination of the Two-Component Systems regulatory network reveals core and accessory regulations across Pseudomonas aeruginosa lineages

Trouillon, J.; Imbert, L.; Villard, A.-M.; Vernet, T.; Attree, I.; Elsen, S.

10.1101/2021.07.23.453361 — microbiology — Posted on 2021-07-24

941 Orfamide-A-mediated bacterial-algal interactions involve specific Ca2+ signalling pathways

Hou, Y.; Bando, Y.; Carrasco Flores, D.; Hotter, V. S.; Schiweck, B.; Arndt, H.-D.; Mittag, M.

10.1101/2021.07.24.453618 — microbiology — Posted on 2021-07-24

942 Targeted drug delivery using Beeswax derived Albendazole-Loaded Solid Lipid Nanoparticles in Haemonchus contortus, an albendazole tolerant nematode.

Sharma, S.; Goel, V.; Kaur, P.; Gadhave, K.; Garg, N.; Singla, L. D.; Choudhury, D.

10.1101/2021.07.24.453620 — microbiology — Posted on 2021-07-24

943 Fecal Microbiota Transplantation Drives Colonic Expression of Immune Activation Genes in a Mouse Model of Antibiotic Use

Moreau, G. B.; Ozbek, H.; Kumar, P.; Frisbee, A.; Leslie, J.; Petri, W. A.

10.1101/2021.07.23.453497 — microbiology — Posted on 2021-07-24

944 Identifying cell-state associated alternative splicing events and their co-regulation

Buen Abad Najar, C. F.; Burra, P.; Yosef, N.; Lareau, L. F.

10.1101/2021.07.23.453605 — genomics — Posted on 2021-07-24

945 Plant pathogen infection risk tracks global crop yields under climate change

Chaloner, T. M.; Gurr, S. J.; Bebber, D. P.

10.1101/2020.04.28.066233 — ecology — Posted on 2021-07-24

946 Reward motivation increases univariate activity but has limited effect on coding of task-relevant information across the frontoparietal cortex

Shashidhara, S.; Erez, Y.

10.1101/609537 — neuroscience — Posted on 2021-07-24

947 Topography of corticopontine projections is controlled by postmitotic expression of the area-mapping gene Nr2f1

Tocco, C.; Ovsthus, M.; Bjaalie, J. G.; Leergaard, T. B.; Studer, M.

10.1101/2021.05.10.443413 — neuroscience — Posted on 2021-07-24

948 Neurobiological underpinnings of rapid white matter plasticity during intensive reading instruction

Huber, E.; Mezer, A.; Yeatman, J.

10.1101/2020.05.28.122499 — neuroscience — Posted on 2021-07-24

949 High Sucrose Diets Contribute to Brain Angiopathy with Impaired Glucose Uptake, and Psychosis-related Higher Brain Dysfunctions in Mice

Hirai, S.; Miwa, H.; Tanaka, T.; Toriumi, K.; Kunii, Y.; Sakamoto, T.; Hino, M.; Izumi, R.; Nagaoka, A.; Yabe, H.; Nakamachi, T.; Shioda, S.; Dan, T.; Miyata, T.; Nishito, Y.; Shimbo, H.; Suzuki, K.; Miyashita, M.; Tomoda, T.; Takatoshi, H.; Horiuchi, J.; Itokawa, M.; Arai, M.; Okado, H.

10.1101/2020.02.14.939546 — neuroscience — Posted on 2021-07-24

950 Mapping Epigenetic Divergence in the Massive Radiation of Lake Malawi Cichlid Fishes

Vernaz, G.; Malinsky, M.; Svardal, H.; Du, M.; Tyers, A. M.; Santos, M. E.; Durbin, R.; Genner, M. J.; Turner, G. F.; Miska, E. A.

10.1101/2020.11.24.383034 — genomics — Posted on 2021-07-24

951 Sex-specific body mass ageing trajectories in adult Asian elephants

Lalande, L. D.; Lummaa, V.; Aung, H. H.; Htut, W.; Nyein, U. K.; Berger, V.; Briga, M.

10.1101/2020.12.17.423208 — evolutionary biology — Posted on 2021-07-24

952 Fructose appetition in "taste-blind" P2X2/P2X3 double knockout mice

Sclafani, A.; Ackroff, K.

10.1101/2021.07.22.453428 — neuroscience — Posted on 2021-07-24

953 A re-analysis of the data in Sharkey et al.'s (2021) minimalist revision reveals that BINs do not deserve names, but BOLD Systems needs a stronger commitment to open science

Meier, R.; Blaimer, B.; Buenaventura, E.; Hartop, E.; von Rintelen, T.; Srivathsan, A.; Yeo, D.

10.1101/2021.04.28.441626 — evolutionary biology — Posted on 2021-07-24

954 MinION barcodes: biodiversity discovery and identification by everyone, for everyone

Srivathsan, A.; Lee, L.; Katoh, K.; Hartop, E.; Kutty, S. N.; Wong, J.; Yeo, D.; Meier, R.

10.1101/2021.03.09.434692 — ecology — Posted on 2021-07-24

955 Differential phase register of Hes1 oscillations with mitoses underlies cell-cycle heterogeneity in ER+ breast cancer cells.

Sabherwal, N.; Rowntree, A.; Marinopoulou, E.; Pettini, T.; Hourihane, S.; Thomas, R.; Kursawe, J.; Soto, X.; Papalopulu, N.

10.1101/2021.01.04.425227 — cell biology — Posted on 2021-07-24

956 Representation of Task Structure in Human Hippocampus and Orbitofrontal Cortex

Mizrak, E.; Bouffard, N.; Libby, L. A.; Boorman, E.; Ranganath, C.

10.1101/794305 — neuroscience — Posted on 2021-07-24

957 Atmospheric plasma jet device for versatile electron microscope grid treatment

Ahn, E.; Tang, T.; Kim, B.; Lee, H. J.; Cho, U.-S.

10.1101/2021.05.11.443639 — biochemistry — Posted on 2021-07-24

958 Phylogenomic analyses of echinoid diversification prompt a re-evaluation of their fossil record

Mongiardino Koch, N.; Thompson, J. R.; Hatch, A. S.; McCowin, M. F.; Armstrong, F.; Coppard, S. E.; Aguilera, F.; Bronstein, O.; Kroh, A.; Mooi, R.; Rouse, G. W.

10.1101/2021.07.19.453013 — evolutionary biology — Posted on 2021-07-24

959 Shifts in leaf senescence across the Northern Hemisphere in response to seasonal warming

Chen, L.; Rossi, S.; G. Smith, N.; Liu, J.

10.1101/2021.07.23.453498 — ecology — Posted on 2021-07-24

960 Characterisation of the role and regulation of Ultrabithorax in sculpting fine-scale leg morphology

Buffry, A. D.; Kittelmann, S.; McGregor, A. P.

10.1101/2020.06.17.152918 — developmental biology — Posted on 2021-07-24

961 Egress of human cytomegalovirus through multivesicular bodies

Flomm, F. J.; Soh, T. K.; Schneider, C.; Britt, H. M.; Thalassinos, K.; Pfitzner, S.; Reimer, R.; Gruenewald, K.; Bosse, J. B.

10.1101/2020.12.31.424954 — microbiology — Posted on 2021-07-24

962 Force and step size of gliding motility in human pathogenic bacterium Mycoplasma pneumoniae

Mizutani, M.; Sasajima, Y.; Miyata, M.

10.1101/2021.05.25.445585 — microbiology — Posted on 2021-07-24

963 An Integrated Workflow for Enhanced Taxonomic and Functional Coverage of the Mouse Faecal Metaproteome

Nalpas, N.; Hoyles, L.; Anselm, V.; Ganief, T.; Martinez-Gili, L.; Grau, C.; Droste-Borel, I.; Davidovic, L.; Altafaj, X.; Dumas, M.-E.; Macek, B.

10.1101/2020.11.17.386938 — microbiology — Posted on 2021-07-24

964 The Plasmodium NOT1-G Paralogue Acts as an Essential Nexus for Sexual Stage Maturation and Parasite Transmission

Hart, K. J.; Power, B. J.; Rios, K. T.; Sebastian, A.; Lindner, S. E.

10.1101/2021.05.25.445483 — microbiology — Posted on 2021-07-24

965 Eliminating accidental deviations to minimize generalization error and maximize replicability: applications in connectomics and genomics

Bridgeford, E. W.; Wang, S.; Yang, Z.; Wang, Z.; Xu, T.; Craddock, C.; Dey, J.; Kiar, G.; Gray-Roncal, W.; Coulantoni, C.; Douville, C.; Priebe, C. E.; Caffo, B.; Milham, M.; Zuo, X.-N.; Consortium for Reliability and Reproducibility, ; Vogelstein, J. T.

10.1101/802629 — neuroscience — Posted on 2021-07-24

966 Mental health explains individual deviations from normative range in cognition-associated brain states

Zhang, W.; Vidaurre, D.; Bijsterbosch, J. D.

10.1101/2021.03.12.435017 — neuroscience — Posted on 2021-07-24

967 EEG Biomarkers of reduced inhibition in human cortical microcircuits in depression

Mazza, F.; Griffiths, J. D.; Hay, E.

10.1101/2021.07.18.452836 — neuroscience — Posted on 2021-07-24

968 A Multi-omics Method Enabled by Sequential Metabolomics and Proteomics for Human Pluripotent Stem Cell-derived Cardiomyocytes

Bayne, E. F.; Simmons, A. D.; Roberts, D. S.; Zhu, Y.; Aballo, T. J.; Wancewicz, B.; Palecek, S.; Ge, Y.

10.1101/2021.06.23.449630 — systems biology — Posted on 2021-07-24

969 DCIS genomic signatures define biology and correlate with clinical outcome: a Human Tumor Atlas Network (HTAN) analysis of TBCRC 038 and RAHBT cohorts

Strand, S. H.; Rivero-Gutierrez, B.; Houlahan, K. E.; Seoane, J. A.; King, L.; Risom, T.; Simpson, L. A.; Vennam, S.; Khan, A.; Cisneros, L.; Hardman, T.; Harmon, B.; Couch, F.; Gallagher, K.; Kilgore, M.; Wei, S.; DeMichele, A.; King, T.; McAuliffe, P. F.; Nangia, J.; Lee, J.; Tseng, J.; Storniolo, A. M.; Thompson, A.; Gupta, G.; Burns, R.; Veis, D. J.; DeSchryver, K.; Zhu, C.; Matusiak, M.; Wang, J.; Zhu, S. X.; Tappenden, J.; Ding, D. Y.; Zhang, D.; Luo, J.; Jiang, S.; Varma, S.; Anderson, L.; Straub, C.; Srivastava, S.; Curtis, C.; Tibshirani, R.; Angelo, R. M.; Hall, A.; Owzar, K.; Polyak

10.1101/2021.06.16.448585 — cancer biology — Posted on 2021-07-24

970 In vivo amyloid-like fibrils produced under stress

Fontana, N. A.; Rosse, A. D.; Watts, A.; Coelho, P. S. R.; Costa-Filho, A. J.

10.1101/2021.02.02.429251 — biophysics — Posted on 2021-07-24

971 gmxapi: a Gromacs-native Python interface for molecular dynamics with ensemble and plugin support

Irrgang, M. E.; Davis, C.; Kasson, P.

10.1101/2021.07.18.452496 — bioinformatics — Posted on 2021-07-24

972 Measuring context dependency in birdsong using artificial neural networks

Morita, T.; Koda, H.; Okanoya, K.; Tachibana, R. O.

10.1101/2020.05.09.083907 — animal behavior and cognition — Posted on 2021-07-24

973 Bayesian model comparison for rare variant association studies

Venkataraman, G. R.; DeBoever, C.; Tanigawa, Y.; Aguirre, M.; Ioannidis, A. G.; Mostafavi, H.; Spencer, C. C. A.; Poterba, T.; Bustamante, C. D.; Daly, M. J.; Pirinen, M.; Rivas, M. A.

10.1101/257162 — genetics — Posted on 2021-07-24

974 A comprehensive framework for handling location error in animal tracking data

Fleming, C. H.; Drescher-Lehman, J.; Noonan, M. J.; Akre, T. S. B.; Brown, D. J.; Cochrane, M. M.; Dejid, N.; DeNicola, V.; DePerno, C. S.; Dunlop, J. N.; Gould, N. P.; Harrison, A.-L.; Hollins, J.; Ishii, H.; Kaneko, Y.; Kays, R.; Killen, S. S.; Koeck, B.; Lambertucci, S. A.; LaPoint, S. D.; Medici, E. P.; Meyburg, B.-U.; Miller, T. A.; Moen, R. A.; Mueller, T.; Pfeiffer, T.; Pike, K. N.; Roulin, A.; Safi, K.; Sechaud, R.; Scharf, A. K.; Shephard, J. M.; Stabach, J. A.; Stein, K.; Tonra, C. M.; Yamazaki, K.; Fagan, W. F.; Calabrese, J. M.

10.1101/2020.06.12.130195 — ecology — Posted on 2021-07-24

975 Coordinated poleward flux of sister kinetochore fibers drives chromosome alignment

Risteski, P.; Bozan, D.; Jagric, M.; Bosilj, A.; Pavin, N.; Tolic, I. M.

10.1101/2020.12.30.424837 — cell biology — Posted on 2021-07-24

976 Autophagosomes fuse to phagosomes and facilitate the degradation of apoptotic cells in Caenorhabditis elegans

Pena-Ramos, O.; Chiao, L.; Liu, X.; Yao, T.; He, H.; Zhou, Z.

10.1101/2021.07.16.452694 — cell biology — Posted on 2021-07-24

977 Targeting "Immunogenic Hotspots" in Dengue and Zika Virus: A Novel Approach to a Common Vaccine

Mahata, D.; Mukherjee, D.; Malviya, V.; Mukherjee, G.

10.1101/2021.07.23.453561 — immunology — Posted on 2021-07-24

978 Bioerosion traces and borings in the Upper Devonian vertebrate remains from the Holy Cross Mountains, Poland Bioerosion in fish remains

Szrek, P.; Dworczak, P. G.; Wilk, O.

10.1101/2021.07.23.453559 — paleontology — Posted on 2021-07-24

979 miR-206 inhibits estrogen-induced proliferation and invasion of ER-α36 positive gastric cancer cells

sheng, X.; Yuan, C.; Yang, Y.; Jiang, X.; Xie, X.; Jun, L.; Xuming, W.

10.1101/2021.07.23.453532 — cancer biology — Posted on 2021-07-24

980 Vision-based monitoring and measurement of bottlenose dolphins' daily habitat use and kinematics

Gabaldon, J.; Zhang, D.; Lauderdale, L.; Miller, L.; Johnson-Roberson, M.; Barton, K.; Shorter, K. A.

10.1101/2021.07.23.453543 — animal behavior and cognition — Posted on 2021-07-23

981 Deficiency in Lyst function leads to accumulation of secreted proteases and predisposition to mechanic stress-induced retinal detachment

Ji, X.; Zhao, L.; Umapathy, A.; Fitzmaurice, B.; Wang, J.; Williams, D. S.; Chang, B.; Naggert, J.; Nishina, P.

10.1101/2021.07.23.453557 — genetics — Posted on 2021-07-24

982 Comparative analysis of transcriptomic profiles among ascidians, zebrafish, and mice: insights from tissue-specific gene expression

Matsubara, S.; Osugi, T.; Shiraishi, A.; Wada, A.; Satake, H.

10.1101/2021.07.23.453541 — evolutionary biology — Posted on 2021-07-23

983 Improving RT-LAMP Detection of SARS-CoV-2 RNA through Primer Set Selection and Combination

Tanner, N.; Zhang, Y.

10.1101/2021.07.23.453545 — molecular biology — Posted on 2021-07-23

984 Fine-tuned method to extract high purified proteins from the seagrass Halophila stipulacea to be used for proteome analyses

Mazzuca, S.; Piro, A.; Anagnostopoulou, V.; Apostolaki, E.

10.1101/2021.07.23.453549 — molecular biology — Posted on 2021-07-23

985 Identification of a distal RXFP1 gene enhancer with differential activity in fibrotic lung fibroblasts involving AP-1

Chen, T.-Y.; Li, X.; Goobie, G. C.; Hung, C.-H.; hamilton, H.; Bahudhanapati, H.; Tan, J.; Kass, D. J.; Zhang, Y.

10.1101/2021.07.23.453556 — molecular biology — Posted on 2021-07-23

986 Insights on the historical biogeography of Philippine native pigs and its relationship with Continental domestic and wild boars

Layos, J. K.; Geromo, R.; Espina, D.; Nishibori, M.

10.1101/2021.07.23.453525 — zoology — Posted on 2021-07-23

987 {-}CardiOvascular examination in awake Orangutans (Pongo pygmaeus pygmaeus): Low-stress Echocardiography including Speckle Tracking imaging (the COOLEST method)

Chetboul, V.; Concordet, D.; Tissier, R.; Vonfeld, I.; Poissonnier, C.; Alvarado, M. P.; Passavin, P.; Gluntz, M.; Lefort, S.; Bourgeois, A.; Duby, D.; Hano, C.; Chai, N.

10.1101/2021.07.23.453539 — zoology — Posted on 2021-07-23

988 Nano-Insecticides Against the Black Cutworm Agrotis ipsilon (Lepidoptera: Noctuidae): Toxicity, Development, Enzyme activity, and DNA Mutagenicity

Awad, M. A. M.; Ibrahim, E.-D. S.; Osman, E. I.; Elmenofy, W. H.; Mahmoud, A. W. M.; Atia, M. A. M.; Moustafa, M. A. M.

10.1101/2021.07.23.453522 — zoology — Posted on 2021-07-23

989 US Dog Importations during the COVID-19 Pandemic: Do we have an erupting problem?

Pieracci, E. G.; Williams, C.; Wallace, R. M.; Kalapura, C.; Brown, C. M.

10.1101/2021.07.23.453524 — scientific communication and education — Posted on 2021-07-23

990 Gastric cancer derived exosomes induce peritoneal mesothelial cell EMT through TGF-β1/Smads pathway to promote peritoneal metastasis

Dong, J.; Zhu, Z.; Cui, G.; Zhang, Z.; Yue, J.; Zhang, Y.; Yao, X.; Huo, M.; Wei, J.; Wang, Q.; Dai, L.; Li, P.; Liu, X.-P.

10.1101/2021.07.23.453534 — cancer biology — Posted on 2021-07-23

991 Performance of Deep Convolutional Neural Network Approaches and Human Level in Detecting Mosquito Species

Jomtarak, R.; Kittichai, V.; Pengsakul, T.; Phatthamolrat, N.; Naing, K. M.; Tongloy, T.; Chuwongin, S.; Boonsang, S.

10.1101/2021.07.23.453554 — bioinformatics — Posted on 2021-07-23

992 Synthesis and characterization of peptide conjugated human serum albumin nanoparticles for targeted cardiac uptake and drug delivery.

Prakash, S.; Lomis, N.; Westfall, S.; Shum-Tim, D.

10.1101/2021.07.23.453538 — bioengineering — Posted on 2021-07-23

993 TELSAM polymers accelerate crystallization of fused target proteins by stabilizing minimal crystal contacts and in the absence of direct inter-TELSAM contacts

Sarath Nawarathnage, S. D.; Soleimani, S.; Mathis, M. H.; Bezzant, B. D.; Ramirez, D. T.; Gajjar, P.; Bunn, D.; Stewart, C.; Smith, T.; Pedroza-Romo, M. J.; Brown, S.; Doukov, T.; Moody, J. D.

10.1101/2021.07.23.453529 — biochemistry — Posted on 2021-07-23

994 Waves and currents decrease the available space in a salmon cage

Johannesen, A.; Patursson, O.; Kristmundsson, J.; Dam, S. P.; Mulelid, M.; Klebert, P.

10.1101/2021.07.23.453560 — animal behavior and cognition — Posted on 2021-07-23

995 Decoding the Neural Signatures of Valence and Arousal From Portable EEG Headset

Garg, N.; Garg, R.; NS, P.; Anand, A.; Abhinav, V. A. S.; Baths, V.

10.1101/2021.07.23.453533 — animal behavior and cognition — Posted on 2021-07-23

996 Effects of pen enrichment on leg health of fast and slower-growing broiler chickens

Güz, B. C.; De Jong, I. C.; Souza Da Silva, C.; Veldkamp, F.; Kemp, B.; Molenaar, R.; van den Brand, H.

10.1101/2021.07.23.453550 — animal behavior and cognition — Posted on 2021-07-23

997 IDENTIFICATION OF HIGH SEED OIL YIELD AND HIGH OLEIC ACID CONTENT IN BRAZILIAN GERMPLASM OF WINTER SQUASH (Cucurbita moschata D.)

Gomes, R. S.; Machado Junior, R.; Almeida, C. F. d.; Oliveira, R. L. d.; Chagas, R. R.; Pereira, E. D.; Delazari, F. T.; Silva, D. J. H. d.

10.1101/2021.07.23.453548 — genetics — Posted on 2021-07-23

998 Population size, density, and ranging behaviour in a key leopard population in the Western Cape, South Africa

Müller, L.; Briers-Louw, W. D.; Seele, B.; Lochner, C.; Amin, R.

10.1101/2021.07.23.453562 — ecology — Posted on 2021-07-23

999 Verification of our empirical understanding of the physiology and ecology of two contrasting plantation species using a trait database

Osone, Y.; Hashimoto, S.; Tanaka, K.

10.1101/2021.07.23.453564 — ecology — Posted on 2021-07-23

1000 Long-term changes in populations of rainforest birds in the Australia Wet Tropics bioregion: a climate-driven biodiversity emergency

Williams, S. E.; de la Fuente, A.

10.1101/2021.07.23.453540 — ecology — Posted on 2021-07-23

1001 Community health and human-animal contacts on the edges of Bwindi Impenetrable National Park, Uganda

Muylaert, R. L.; Davidson, B.; Ngabirano, A.; Kalema-Zikusoka, G.; MacGregor, H.; Lloyd-Smith, J. O.; Fayaz, A.; Knox, M.; Hayman, D. T. S.

10.1101/2021.07.23.453553 — ecology — Posted on 2021-07-23

1002 A real-time assay for cell-penetrating peptide-mediated delivery of molecular cargos

McMurry, J. L.; Gentry, S. B.; Nowak, S. J.; Ni, X.; Hill, S. A.; Wade, L. R.; Clark, W. R.; Keelaghan, A. P.; Morris, D. P.

10.1101/2021.07.23.453555 — cell biology — Posted on 2021-07-23

1003 Buenos Aires, June 2021Inhibition of Mitochondrial Fission by Drp-1 Blockade by Short-Term Leptin and Mdvi-1 Treatment Improves White Adipose Tissue Abnormalities in Obesity and Diabetes

Finocchietto, P.; Perez, H.; Blanco, G.; Miksztowicz, V.; Marotte, C.; Morales, C.; Peralta, J.; Berg, G.; Poderoso, C.; Poderoso, J. J.; Carreras, M. C.

10.1101/2021.07.23.453523 — molecular biology — Posted on 2021-07-23

1004 Highly selective Cooperative Primers for multiplex detection of rare mutations

Kent, J. O.; Christensen, M. C.

10.1101/2021.07.23.453558 — molecular biology — Posted on 2021-07-23

1005 Differential mitochondrial protein interaction profile between human translocator protein and its A147T polymorphism variant

Asih, P. R.; Plojak, A.; Kassiou, M.; Ke, Y.; Ittner, L. M.

10.1101/2021.07.23.453531 — molecular biology — Posted on 2021-07-23

1006 Gene editing in bacteria by CRISPR-Cas9 via SpCas9/sgRNA ribonucleoprotein complexes

Morales-Rios, E.; Arroyo-Olarte, R. D.; Bravo Rodriguez, R. N.

10.1101/2021.07.23.453544 — molecular biology — Posted on 2021-07-23

1007 Evaluation of the sensitivity and specificity of three diagnostic tests for Coxiella burnetii infection in cattle and buffaloes in Punjab (India) using Bayesian latent class analysis

Meletis, E.; Keshavamurthy, R.; Singh, B.; Aulakh, R.; Dhand, N.; Kostoulas, P.

10.1101/2021.07.23.453536 — microbiology — Posted on 2021-07-23

1008 Virulence and antimicrobial resistance profile of non-typhoidal Salmonella enterica serovars recovered from poultry processing environments at wet markets in Dhaka, Bangladesh

Siddiky, N. A.; Sarker, M. S.; Khan, M. S. R.; Rahman, M. T.; Kafi, M. A.; Samad, M. A.

10.1101/2021.07.23.453547 — microbiology — Posted on 2021-07-23

1009 TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction

Khan, H.; Winstone, H.; Jimenez-Guardeno, J.; Graham, C.; Doores, K.; Goujon, C.; Matthews, D.; Davidson, A.; Rihn, S.; Palmarini, M.; Neil, S.; Malim, M.

10.1101/2021.07.23.453488 — microbiology — Posted on 2021-07-23

1010 Identification and Validation of N-Acetylputrescine in Combination With Non-Canonical Clinical Features As a Parkinsons Disease Biomarker Panel

Peng, K.-W.; Klotz, A.; Guven, A.; Kapadnis, U.; Ravipaty, S.; Tolstikov, V.; Vemulapalli, V.; Rodrigues, L. O.; Li, H.; Kellogg, M. D.; Kausar, F.; Rees, L.; Sarangarajan, R.; Schüle, B.; Langston, W.; Narain, P. P.; Narain, N. R.; Kiebish, M. A.

10.1101/2021.07.23.453542 — neuroscience — Posted on 2021-07-23

1011 Automated identification of piglet brain tissue from MRI images using Region-Based Convolutional Neural Networks

Stanke, K. L.; Larsen, R.; Rund, L.; Leyshon, B. J.; Louie, A.; Steelman, A.

10.1101/2021.07.23.453526 — neuroscience — Posted on 2021-07-23

1012 Transcriptome and metabolome analyses reveal pathways associated with fruit color in plum (Prunus salicina Lindl.)

Chen, L.; Wang, X.; Cui, L.; Zhang, Y.

10.1101/2021.07.23.453563 — plant biology — Posted on 2021-07-23

1013 Life history of Dactylopius opuntiae (Hemiptera: Dactylopiidae) on Moroccan resistant cactus germplasm

EL AALAOUI, M.; Sbaghi, M.

10.1101/2021.07.23.453565 — pathology — Posted on 2021-07-23

1014 Expression of Spred2 in the urothelial tumorigenesis of the urinary bladder

Oda, S.; Fujisawa, M.; Chunning, L.; Ito, T.; Yamaguchi, T.; Yoshimura, T.; Matsukawa, A.

10.1101/2021.07.23.453537 — pathology — Posted on 2021-07-23

1015 Effects of climatic change on the potential distribution of Lycoriella species (Diptera: Sciaridae) of economic importance

Marques, R.; Duarte, J. L.; Fonseca, A. d.; Krüger, R. F.; Silva, U.; Osorio-Olvera, L.; Contreras-Diaz, R. G.; Jimenez-Garcia, D.

10.1101/2021.07.23.453546 — bioinformatics — Posted on 2021-07-23

1016 Molecular characterization and functional annotation of a hypothetical protein (TDB29877.1) from probiotic bacteria Lactobacillus acidophilus: an in-silico approach

Rabbani, M. A. G.

10.1101/2021.07.23.453527 — bioinformatics — Posted on 2021-07-23

1017 Coordination of di-acetylated histone ligands by the ATAD2 bromodomain

Evans, C. M.; Phillips, M.; Malone, K. L.; Tonelli, M.; Cornilescu, G.; Cornilescu, C.; Holton, S.; Gorjanacz, M.; Wang, L.; Carlson, S.; Gay, J. C.; Nix, J. C.; Demeler, B.; Markley, J. L.; Glass, K. C.

10.1101/2021.07.23.453464 — biochemistry — Posted on 2021-07-23

1018 Characterization of BLUF-photoreceptors present in Acinetobacter nosocomialis.

Abatedaga, I.; Perez Mora, B.; Tuttobene, M.; Müller, G.; Biancotti, D.; Borsarelli, C. D.; Valle, L.; Mussi, M. A.

10.1101/2021.07.23.453528 — biochemistry — Posted on 2021-07-23

1019 Female Bengalese finches recognize their fathers song as sexually attractive

Fujii, T. G.; Okanoya, K.

10.1101/2021.07.23.453535 — animal behavior and cognition — Posted on 2021-07-23

1020 Combined impacts of climate and land use change and the future of Neotropical bat biodiversity

Goncalves, F.; Sales, L. P.; Galetti, M.; Pires, M. M.

10.1101/2021.07.23.453383 — ecology — Posted on 2021-07-23

1021 Transcriptome analysis of Pseudomonas aeruginosa biofilm infection in an ex vivo pig model of the cystic fibrosis lung

Harrington, N. E.; Littler, J. L.; Harrison, F.

10.1101/2021.07.23.453509 — microbiology — Posted on 2021-07-23

1022 The "neural shift" of sleep quality and cognitive ageing: A resting-state MEG study of transient neural dynamics

Tibon, R.; Cam-CAN, ; Tsvetanov, K. A.

10.1101/2021.07.23.453491 — neuroscience — Posted on 2021-07-23

1023 The dopamine dip amplitude is a quantitative measure of disappointment

Shikano, Y.; Yagishita, S.; Tanaka, K. F.; Takata, N.

10.1101/2021.07.23.453499 — neuroscience — Posted on 2021-07-23

1024 Phenomics data processing: Extracting temperature dose-response curves from repeated measurements

Roth, L.; Piepho, H.-P.; Hund, A.

10.1101/2021.07.23.453040 — plant biology — Posted on 2021-07-23

1025 Coordinated activation of both TGFβ and BMP canonical pathways regulates autophagy and tissue regeneration in acetaminophen induced liver injury

Stavropoulos, A.; Divolis, G.; Manioudaki, M.; Gavriil, A.; Kloukina, I.; Perrea, D. N.; Sountoulidis, A.; Ford, E.; Doulou, A.; Apostolidou, A.; Katsantoni, E.; Ritvos, O.; Germanidis, G.; Xilouri, M.; Sideras, P.

10.1101/2021.07.23.453185 — physiology — Posted on 2021-07-23

1026 Maternal microbiota Bifidobacterium promotes placental vascularization, nutrient transport and fetal growth in mice

Lopez-Tello, J.; Schofield, Z.; Kiu, R.; Dalby, M. J.; van Sinderen, D.; Le Gall, G.; Sferruzzi-Perri, A. N.; Hall, L. J.

10.1101/2021.07.23.453407 — physiology — Posted on 2021-07-23

1027 EZH2 inhibition enhances TRAIL responses in multiple myeloma but not in quiescent cells

Arhoma, A.; Southan, J.; Chantry, A. D.; Haywood-Small, S. L.; Cross, N. A.

10.1101/2021.07.23.453217 — cancer biology — Posted on 2021-07-23

1028 Transfer Learning Compensates Limited Data, Batch-Effects, And Technical Heterogeneity In Single-Cell Sequencing

Park, Y.; Hauschild, A.-C.; Heider, D.

10.1101/2021.07.23.453486 — bioinformatics — Posted on 2021-07-23

1029 Generative Adversarial Network augmented the gut microbiome-based health index by profoundly improved discrimination power

Li, Y.; Xie, G.; Zha, Y.; Ning, K.

10.1101/2021.07.23.453477 — bioinformatics — Posted on 2021-07-23

1030 Biocompatible soft hydrogel lens as topical implants for diabetic retinopathy

Sadasivam, R.; Packirisamy, G.; Goswami, M.

10.1101/2021.07.23.453466 — bioengineering — Posted on 2021-07-23

1031 Using Deep Learning to Count Monarch Butterflies in Dense Clusters

Patel, S.; Kulkarni, A.; Mukhopadhyay, A.; Gujar, K.; Roode, J. d.

10.1101/2021.07.23.453502 — bioengineering — Posted on 2021-07-23

1032 Mitochondrial DNA variation across 56,434 individuals in gnomAD

Laricchia, K. M.; Lake, N. J.; Watts, N. A.; Shand, M.; Haessly, A.; Gauthier, L.; Benjamin, D.; Banks, E.; Soto, J.; Garimella, K.; Emery, J.; Genome Aggregation Database Consortium, ; Rehm, H. L.; MacArthur, D. G.; Tiao, G.; Lek, M. V.; Mootha, V. K.; Calvo, S. E.

10.1101/2021.07.23.453510 — genomics — Posted on 2021-07-23

1033 Nematode Small RNA Pathways in the Absence of piRNAs

Zagoskin, M.; Wang, J.; Neff, A. T.; Veronezi, G. M. B.; Davis, R. E.

10.1101/2021.07.23.453445 — genomics — Posted on 2021-07-23

1034 Selection of reference genes for quantitative analysis of microRNA expression in three cancers.

Veryaskina, Y.; Titov, S. E.; Ivanov, M. K.; Ruzankin, P. S.; Tarasenko, A. S.; Shevchenko, S. P.; Kovynev, I. B.; Stupak, E. V.; Pospelova, T. I.; Zhimulev, I. F.

10.1101/2021.07.23.453530 — genetics — Posted on 2021-07-23

1035 Regulation of sedimentation rate shapes the evolution of multicellularity in a unicellular relative of animals.

Dudin, O.; Wielgoss, S.; New, A. M.; Ruiz-Trillo, I.

10.1101/2021.07.23.453070 — evolutionary biology — Posted on 2021-07-23

1036 Shifts in leaf senescence across the Northern Hemisphere in response to seasonal warming

Chen, L.; Rossi, S.; G. Smith, N.; Liu, J.

10.1101/2021.07.23.453498 — ecology — Posted on 2021-07-23

1037 DNA-damage induced cell death in yap1;wwtr1 mutant epidermal basal cells

Lai, J. K.; Toh, P. J.; Cognart, H. A.; Chouhan, G.; Saunders, T. E.

10.1101/2021.07.23.453490 — developmental biology — Posted on 2021-07-23

1038 Microtubule-based mitotic spindles contain a micron-sized mixed-nucleotide zone

Castrogiovanni, C.; Inchingolo, A. V.; Harrison, J. U.; Dudka, D.; Sen, O.; Burroughs, N. J.; McAinsh, A. D.; Meraldi, P.

10.1101/2021.07.23.453504 — cell biology — Posted on 2021-07-23

1039 Chlamydomonas reinhardtii exhibits stress memory in the accumulation of triacylglycerols induced by nitrogen deprivation.

Mikulski, P.; Santos-Aberturas, J.

10.1101/2021.07.23.453471 — molecular biology — Posted on 2021-07-23

1040 Transcriptional Landscape of Ectomycorrhizal Fungi and Their Host Provide Insight into N Uptake from Forest Soil

Rivera Perez, C. A.; Janz, D.; Schneider, D.; Daniel, R.; Polle, A.

10.1101/2021.07.23.453179 — microbiology — Posted on 2021-07-23

1041 Phage Resistance Mechanisms Increase Colistin Sensitivity in Acinetobacter baumannii

Wang, X.; Loh, B.; Yu, Y.; Hua, X.; Leptihn, S.

10.1101/2021.07.23.453473 — microbiology — Posted on 2021-07-23

1042 Probiotic consortia improve anti-viral immunity to SARS-CoV-2 in ferrets

Lehtinen, M.; Kumar, R.; Zabel, B.; Makela, S. M.; Nedveck, D.; Tang, P.; Latvala, S.; Guery, S.; Budinoff, C. R.

10.1101/2021.07.23.453521 — immunology — Posted on 2021-07-23

1043 Orphan cytochrome P450 20A1 CRISPR/Cas 9 mutants and neurobehavioral phenotypes in zebrafish

Brun, N. R.; Salanga, M. C.; Mora-Zamorano, F. X.; Lamb, D. C.; Goldstone, J. V.; Stegeman, J. J.

10.1101/2021.07.23.453406 — pharmacology and toxicology — Posted on 2021-07-23

1044 Intrinsically disordered N-terminal domain (NTD) of p53 interacts with mitochondrial PTP regulator Cyclophilin D

Zhao, J.; Liu, X.; Blayney, A.; Gandy, L.; Zhang, F.; Linhardt, R. J.; Zhang, Y.; Chen, J.; Baines, C.; Loh, S. N.; Wang, C.

10.1101/2021.07.23.453429 — biochemistry — Posted on 2021-07-23

1045 Mesalamine Reduces Intestinal ACE2 Expression Without Modifying SARS-CoV-2 Infection or Disease Severity in Mice.

Alvarado, D. M.; Son, J.; Thackray, L. B.; Diamond, M.; Ding, S.; Ciorba, M. A.; Washington University IBD Investigators Group,

10.1101/2021.07.23.453393 — microbiology — Posted on 2021-07-23

1046 The in vitro and in vivo potency of CT-P59 against Delta and its associated variants of SARS-CoV-2

Ryu, D.-K.; Woo, H.-M.; Kang, B.; Noh, H.; Kim, J.-I.; Seo, J.-M.; Kim, C.; Kim, M.; Kim, J.-W.; Kim, N.; Jeon, P.; Lee, H.; Yang, J.-S.; Kim, K.-C.; Lee, J.-Y.; Lee, M.-H.; Oh, S.-S.; Chung, H.-Y.; Kwon, K.-S.; Lee, S.-Y.

10.1101/2021.07.23.453472 — microbiology — Posted on 2021-07-23

1047 Effective presence of antibodies against common human coronavirus in IgG immunoglobulin medicinal products.

Diez, J.-M.; Romero, C.; Gajardo, R.

10.1101/2021.07.23.453571 — immunology — Posted on 2021-07-23

1048 Memories in a network with excitatory and inhibitory plasticity are encoded in the spiking irregularity

Gallinaro, J. V.; Clopath, C.

10.1101/2021.07.22.453370 — neuroscience — Posted on 2021-07-23

1049 Novel Class of Psychedelic Iboga Alkaloids Disrupts Opioid Addiction States

Havel, V.; Kruegel, A. C.; Bechand, B.; McIntosh, S.; Stallings, L.; Hodges, A.; Wulf, M. G.; Nelson, M.; Hunkele, A.; Ansonoff, M.; Pintar, J. E.; Hwu, C.; Abi-Gerges, N.; Zaidi, S. A.; Katritch, V.; Yang, M.; Javitch, J. A.; Majumdar, S.; Hemby, S. E.; Sames, D.

10.1101/2021.07.22.453441 — pharmacology and toxicology — Posted on 2021-07-23

1050 How clustered protocadherin binding specificity is tuned for neuronal self/non-self-recognition

Goodman, K. M.; Katsamba, P. S.; Rubinstein, R.; Ahlsen, G.; Bahna, F.; Mannepalli, S.; Dan, H.; Sampogna, R.; Shapiro, L.; Honig, B.

10.1101/2021.07.22.453400 — biophysics — Posted on 2021-07-23

1051 Understanding the role of memory re-activation and cross-reactivity in the defense against SARS-CoV-2

Denninger, V.; Xu, C. K.; Meisl, G.; Morgunov, A. S.; Fiedler, S.; Ilsley, A.; Emmenegger, M.; Malik, A. Y.; Piziorska, M. A.; Schneider, M. M.; Devenish, S. R. A.; Kosmoliaptsis, V.; Aguzzi, A.; Fiegler, H.; Knowles, T. P. J.

10.1101/2021.07.23.453352 — biophysics — Posted on 2021-07-23

1052 PDZ-containing proteins targeted by the ACE2 receptor

Caillet-Saguy, C.; Wolff, N.

10.1101/2021.07.23.453470 — biochemistry — Posted on 2021-07-23

1053 A Highly Potent SARS-CoV-2 Blocking Lectin Protein

Ahan, R. E.; Hanifehnezhad, A.; Sahin Kehribar, E.; Oguzoglu, T. C.; Foldes, K.; Ozcelik, C. E.; Filazi, N.; Oztop, S.; Onder, S. C.; Bozkurt, E. U.; Ergunay, K.; Ozkul, A.; Seker, U.

10.1101/2021.07.22.453309 — biochemistry — Posted on 2021-07-23

1054 Faces of men with high serum testosterone are less attractive for women during the fertility phase of the menstrual cycle

Krejza, J.; Sledziewski, R.; Tabedzki, M.; Chen, R.; Krzystanek, E.; Arkuszewski, M.; Odachowska, M.; Kwiatkowska, K.; Marynowska, M.; Rogowski, M.; Ustymowicz, A.

10.1101/2021.07.22.453412 — evolutionary biology — Posted on 2021-07-23

1055 SARS-CoV-2 Exploits Sexually Dimorphic and Adaptive IFN and TNFa Signaling to Gain Entry into Alveolar Epithelium

Giancotti, F.; Wang, Y.; Gurrapu, S.; Chen, H.; Laudato, S.; Caggiano, E.; Jiang, Y.; Ling, H.-H.

10.1101/2021.07.23.453505 — immunology — Posted on 2021-07-23

1056 The precedence effect in spatial hearing emerges only late in the auditory pathway

Li, K.; Auksztulewicz, R.; Chan, C. H. K.; Mishra, A. P.; Schnupp, J. W. H.

10.1101/2021.07.21.453295 — neuroscience — Posted on 2021-07-23

1057 AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery

Potjewyd, F. M.; Annor-Gyamfi, J. K.; Aube, J.; Chu, S.; Conlon, I. L.; Frankowski, K. J.; Guduru, S. K. R.; Hardy, B. P.; Hopkins, M. D.; Kinoshita, C.; Kireev, D. B.; Mason, E. R.; Moerk, C. T.; Nwogbo, F.; Pearce, K. H.; Richardson, T.; Rogers, D. A.; Soni, D. M.; Stashko, M.; Wang, X.; Wells, C.; Willson, T. M.; Frye, S. V.; Young, J. E.; Axtman, A. D.

10.1101/2021.07.22.453404 — neuroscience — Posted on 2021-07-23

1058 Harnessing the functional diversity of plant cystatins to design inhibitor variants highly active against herbivorous arthropod digestive proteases

Tremblay, J.; Goulet, M.-C.; Vorster, J.; Goulet, C.; Michaud, D.

10.1101/2021.07.22.453419 — plant biology — Posted on 2021-07-23

1059 Integrative proteomics and phosphoproteomics reveals phosphorylation networks involved in the maintenance and expression of embryogenic competence in sugarcane callus

Xavier, L. R.; Almeida, F. A.; Pinto, V. B.; Passamani, L. Z.; Santa-Catarina, C.; Filho, G. A. d. S.; Mooney, B. P.; Thelen, J. J.; Silveira, V.

10.1101/2021.07.22.453415 — plant biology — Posted on 2021-07-23

1060 OPUS-Rota4: A Gradient-Based Protein Side-Chain Modeling Framework Assisted by Deep Learning-Based Predictors

Xu, G.; Wang, Q.; Ma, J.

10.1101/2021.07.22.453446 — bioinformatics — Posted on 2021-07-23

1061 A human ensemble cell atlas (hECA) enables in data cell sorting

Chen, S.; Luo, Y.; Gao, H.; Li, F.; Li, J.; Chen, Y.; You, R.; Hao, M.; Bian, H.; Xi, X.; Li, W.; Li, W.; Ye, M.; Meng, Q.; Zou, Z.; Li, C.; Li, H.; Zhang, Y.; Cui, Y.; Wei, L.; Chen, F.; Wang, X.; Lv, H.; Hua, K.; Jiang, R.; Zhang, X.

10.1101/2021.07.21.453289 — bioinformatics — Posted on 2021-07-23

1062 Methylartist: Tools for Visualising Modified Bases from Nanopore Sequence Data

Cheetham, S. W.; Kindlova, M.; Ewing, A. D.

10.1101/2021.07.22.453313 — bioinformatics — Posted on 2021-07-23

1063 iPSC-derived Vascular Smooth Muscle Cells in a Fibronectin Functionalized Collagen Scaffold Augment Endothelial Cell Morphogenesis

Duan, K.; Dash, B. C.; Sasson, D.; Hsia, H.

10.1101/2021.07.22.453420 — bioengineering — Posted on 2021-07-23

1064 Accelerating long-read analysis on modern CPUs

Kalikar, S.; Jain, C.; Md, V.; Misra, S.

10.1101/2021.07.21.453294 — genomics — Posted on 2021-07-23

1065 Copy number variations with adaptive potential in caribou (Rangifer tarandus): genome architecture and new annotated genome assembly

Prunier, J.; Carrier, A.; Gilbert, I.; Poisson, W.; Albert, V.; Taillon, J.; Bourret, V.; Cote, S. D.; Droit, A.; Robert, C.

10.1101/2021.07.22.453386 — genomics — Posted on 2021-07-23

1066 The interaction between a parasite and sub-optimal temperatures contributes to honey bee decline

Frizzera, D.; Andreuzza, L.; Boaro, G.; D'Agaro, M.; Del Fabbro, S.; Zanni, V.; Annoscia, D.; Nazzi, F.

10.1101/2021.07.22.453350 — ecology — Posted on 2021-07-23

1067 Convergence of MCR-8.2 and chromosome-mediated resistance to colistin and tigecycline in an NDM-5-producing ST656 Klebsiella pneumoniae from a lung transplant patient

Zhao, J.; Li, Z.; Zhang, Y.; Liu, X.; Xiong, Z.; Fan, Y.; Zou, X.; lu, B.; Cao, B.

10.1101/2021.07.21.453302 — microbiology — Posted on 2021-07-23

1068 Baseline psychological traits contribute to Lake Louise Acute Mountain Sickness score at high altitude

Talks, B. J.; Campbell, C.; Larcombe, S. J.; Marlow, L.; Finnegan, S. L.; Lewis, C. T.; Lucas, S. J. E.; Harrison, O. K.; Pattinson, K. T. S.

10.1101/2021.07.22.451589 — neuroscience — Posted on 2021-07-23

1069 Discriminative and affective touch converge: Somatosensory cortex represents A-beta input in a CT-like manner

Schirmer, A.; Lai, O.; McGlone, F.; Cham, C.; Lau, D.

10.1101/2021.07.21.453292 — neuroscience — Posted on 2021-07-23

1070 Not all smokers are alike: The hidden cost of sustained attention during nicotine abstinence

Deshpande, H. U.; Fedota, J. R.; Castillo, J.; Salmeron, B. J.; Ross, T. J.; Stein, E. A.

10.1101/2021.07.22.453142 — neuroscience — Posted on 2021-07-23

1071 Cerebral coherence in task-based fMRI hyperscanning: a new trick to an old dog

Wang, L.-S.; Cheng, J.-T.; Hsu, I.-J.; Liou, S.; Kung, C.-C.; Chen, D.-Y.; Weng, M.-H.

10.1101/2021.07.21.452832 — neuroscience — Posted on 2021-07-23

1072 High-speed imaging of light-induced photoreceptor microsaccades in compound eyes

Kemppainen, J.; Mansour, N.; Takalo, J.; Juusola, M.

10.1101/2021.07.22.453335 — neuroscience — Posted on 2021-07-23

1073 Characterization of cocaine addiction-like behavior in heterogeneous stock rats

de Guglielmo, G.; Carrette, L.; Kallupi, M.; Brennan, M.; Boomhower, B.; Maturin, L.; Conlisk, D.; Sedighim, S.; Tieu, L.; Pavlich, M.; Martinez, A.; Velarde, N.; Kononoff, J.; Kimbrough, A.; Simpson, S.; Smith, L.; Shankar, K.; Krook, C.; Avelar, A.; Schweitzer, P.; Woods, L. S.; Palmer, A. A.; George, O.

10.1101/2021.07.22.453410 — neuroscience — Posted on 2021-07-23

1074 Cross immunity protection and antibody dependent enhancement: A distributed delay dynamic model

Steindorf, V.; Oliva, S.

10.1101/2021.07.22.453430 — systems biology — Posted on 2021-07-23

1075 Proteome Profiling of Cerebrospinal Fluid Reveals Novel Biomarker Candidates for Parkinson's Disease

Karayel, O.; Virreira Winter, S.; Padmanabhan, S.; Kuras, Y. I.; Vu, D. T.; Tuncali, I.; Merchant, K.; Wills, A.-M.; Scherzer, C. R.; Mann, M.

10.1101/2021.07.22.453322 — systems biology — Posted on 2021-07-23

1076 THESEUS1 modulates cell wall stiffness and abscisic acid production in Arabidopsis thaliana

Bacete, L.; Schulz, J.; Engelsdorf, T.; Bartosova, Z.; Vaahtera, L.; Yan, G.; Gerhold, J.; Ticha, T.; Ovstebo, C.; Gigli-Bisceglia, N.; Starheim, S. J.; Margueritat, J.; Kollist, H.; Dehoux, T.; McAdam, S.; Hamann, T.

10.1101/2021.07.22.453418 — plant biology — Posted on 2021-07-23

1077 Pectin remodeling belongs to a homeostatic system and triggers transcriptomic and hormonal modulations

Jobert, F.; Guenin, S.; Voxeur, A.; Lee, K. J.; Bouton, S.; Senechal, F.; Hocq, L.; Mongelard, G.; Demailly, H.; Amakorova, P.; Strnad, M.; Vernhettes, S.; Mouille, G.; Pilard, S.; Knox, P.; Novak, O.; Pelloux, J.; Gutierrez, L.

10.1101/2021.07.22.453319 — plant biology — Posted on 2021-07-23

1078 Leptin protects against the development and expression of cocaine addiction-like behavior in heterogenous stock rats

Carrette, L. L. G.; Corral, C.; Crook, C.; Boomhower, B.; Brennan, M.; Ortez, C.; Shankar, K.; Simpson, S.; Maturin, L.; de Guglielmo, G.; Solberg-Woods, L.; Palmer, A. A.; George, O.

10.1101/2021.07.22.453426 — physiology — Posted on 2021-07-23

1079 Beneficial effects of the AFO-202 and N-163 strains of Aureobasidium pullulans produced 1,3-1,6 beta glucans on non-esterified fatty acid levels in obese diabetic KKAy mice: A comparative study

Ikewaki, N.; Onaka, T.; Ikeue, Y.; Nagataki, M.; Kurosawa, G.; Dedeepiya, V. D.; Rajmohan, M.; Vaddi, S.; Senthilkumar, R.; Preethy, S.; Abraham, S. J.

10.1101/2021.07.22.453362 — pharmacology and toxicology — Posted on 2021-07-23

1080 Combination of High Dose Rate Radiations (10X FFF/2400 MU/min/10 MV X-rays) and Paclitaxel Selectively Eliminates Melanoma Cells

Lodhi, N.; Sarojini, S.; Keck, M.; Nagpal, P.; Chiu, Y. M.; Parvez, Z.; Adrianzen, L.; Suh, K. S.

10.1101/2021.07.22.453100 — cancer biology — Posted on 2021-07-23

1081 The MKRN1-BRAF exon4-exon9 fusion is a targetable oncogenic driver

Girtman, M. A.; Richmond, C. S.; Kenny, P. A.

10.1101/2021.07.22.453427 — cancer biology — Posted on 2021-07-23

1082 Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A

Narayan, S.; Raza, A.; Mahmud, I.; Koo, N.; Garrett, T.; Law, M. E.; Law, B. K.; Sharma, A. K.

10.1101/2021.07.21.453259 — cancer biology — Posted on 2021-07-23

1083 A Workflow for Rapid Unbiased Quantification of Fibrillar Feature Alignment in Biological Images

Marcotti, S.; de Freitas, D. B.; Troughton, L. D.; Kenny, F. N.; Shaw, T. J.; stramer, b.; Oakes, P. W.

10.1101/2021.07.22.453401 — biophysics — Posted on 2021-07-23

1084 A competitive advantage through fast dead matter elimination in confined cellular aggregates

Pollack, Y. G.; Bittihn, P.; Golestanian, R.

10.1101/2021.07.22.453340 — biophysics — Posted on 2021-07-23

1085 Switching Promotor Recognition of Phage RNA Polymerase in Silico Following Path along Lab Directed Evolution

E, C.; Dai, L.; Yu, J.

10.1101/2021.07.22.453425 — biophysics — Posted on 2021-07-23

1086 Linearly polarized excitation enhances signals from fluorescent voltage indicators

Bloxham, W.; Brinks, D.; Kheifets, S.; Cohen, A. E.

10.1101/2021.07.21.453006 — biophysics — Posted on 2021-07-23

1087 Non-specific adhesive forces between filaments and membraneless organelles

Böddeker, T. J.; Rosowski, K. A.; Berchtold, D.; Emmanouilidis, L.; Han, Y.; Allain, F. H. T.; Style, R. W.; Pelkmans, L.; Dufresne, E. R.

10.1101/2021.07.22.453380 — biophysics — Posted on 2021-07-23

1088 Context dependency of nucleotide probabilities and variants in human DNA

Liang, Y.; Gronbaek, C.; Fariselli, P.; Krogh, A.

10.1101/2021.07.22.453351 — bioinformatics — Posted on 2021-07-23

1089 A Combination Strategy of Solubility Enhancers for Effective Production of Soluble and Bioactive Human Enterokinase

Kwon, J.; Cho, H.; Kim, S.; Ryu, Y.; Lee, J.-j.

10.1101/2021.07.22.453328 — bioengineering — Posted on 2021-07-23

1090 Enzyme-constrained models predict the dynamics of Saccharomyces cerevisiae growth in continuous, batch and fed-batch bioreactors

Moreno-Paz, S.; Schmitz, J.; Martins dos Santos, V. A. P.; Suarez-Diez, M.

10.1101/2021.07.22.453334 — bioengineering — Posted on 2021-07-23

1091 Polymer-Conjugated Carbon Nanotubes for Biomolecule Loading

Jackson, C. T.; Wang, J. W.; Gonzalez-Grandio, E.; Goh, N. S.; Mun, J.; Krishnan, S.; Landry, M. P.

10.1101/2021.07.22.453422 — biochemistry — Posted on 2021-07-23

1092 Groping in the fog: soaring migrants exhibit wider scatter and do not properly adjust their flight in response to wind under low visibility conditions

Becciu, P.; Panuccio, M.; Dell'Omo, G.; Sapir, N.

10.1101/2021.07.22.453357 — animal behavior and cognition — Posted on 2021-07-23

1093 3D imaging reveals potential anticipatory responses to increasing intraspecific competition in the Drosophila male reproductive system

Morimoto, J.; Barcellos, R.; Schoborg, T. A.; Nogueira, L. P.; Colaco, M. V.

10.1101/2021.07.22.453343 — evolutionary biology — Posted on 2021-07-23

1094 An ancestral burst of regulatory and protein innovation drives divergent implantation in eutherian mammals.

Taylor, A. S.; Tinning, H.; Ovchinnikov, V.; Smith, W.; Pullinger, A. L.; Sutton, R. A.; Constantinides, B.; Wang, D.; Forde, N.; O'Connell, M. J.

10.1101/2021.07.22.453388 — evolutionary biology — Posted on 2021-07-23

1095 Complement Regulator Factor H is a Cofactor for Thrombin in both Pro- and Anticoagulant Roles

McCluskey, G.; Davies, G. E.; Velounias, R. L.; Hughes, T. R.; Morgan, B. P.; Preston, R. J.; Collins, P. W.; Jenkins, P. V.; Heurich, M.

10.1101/2021.07.22.452893 — immunology — Posted on 2021-07-23

1096 A transmissible γδ intraepithelial lymphocyte hyperproliferative phenotype is associated with the intestinal microbiota and confers protection against acute infection.

Jia, L.; Wu, G.; Alonso, S.; Zhao, C.; Lemenze, A.; Lam, Y. Y.; Zhao, L.; Edelblum, K. L.

10.1101/2021.07.22.453366 — immunology — Posted on 2021-07-23

1097 Preconditioning by voluntary wheel running attenuates later neuropathic pain via Nrf2 antioxidant signaling in rats

Green-Fulgham, S. M.; Harland, M. E.; Ball, J. B.; D'Angelo, H.; Dreher, R. A.; Li, J.; Lacagnina, M. J.; Lorca, S. A.; Kwilasz, A. J.; Maier, S. F.; Watkins, L. R.; Grace, P. M.

10.1101/2021.07.21.452532 — neuroscience — Posted on 2021-07-23

1098 Drop, Swap, and Generate: A Self-Supervised Approach for Generating Neural Activity

Liu, R.; Azabou, M.; Dabagia, M.; Lin, C.-H.; Azar, M. G.; Hengen, K. B.; Valko, M.; Dyer, E. L.

10.1101/2021.07.21.453285 — neuroscience — Posted on 2021-07-23

1099 Effects of reward history on decision-making and movement vigor

Sukumar, S.; Shadmehr, R.; Ahmed, A. A.

10.1101/2021.07.22.453376 — neuroscience — Posted on 2021-07-23

1100 Dissection of brain-wide spontaneous and functional somatosensory circuits by fMRI with optogenetic silencing

Jung, W. B.; Jiang, H.; Lee, S.; Kim, S.-G.

10.1101/2021.07.22.453311 — neuroscience — Posted on 2021-07-23

1101 Neural and computational processes of accelerated perceptual awareness and decisions: A 7T fMRI Study

Kalhan, S.; McFadyen, J.; Tsuchiya, N.; Garrido, M.

10.1101/2021.07.22.453451 — neuroscience — Posted on 2021-07-23

1102 Prolonged Pain Reliably Slows Peak Alpha Frequency by Reducing Fast Alpha Power

Furman, A. J.; Prohorenko, M.; Keaser, M. L.; Zhang, J.; Chen, S.; Mazaheri, A.; Seminowicz, D. A.

10.1101/2021.07.22.453260 — neuroscience — Posted on 2021-07-23

1103 Breakout Rooms, Polling, and Chat, Oh My! The Development and Validation of Online COPUS

Pusey, T. S.; Valencia, A. P.; Signorini, A.; Kranzfelder, P.

10.1101/2021.07.21.453286 — scientific communication and education — Posted on 2021-07-23

1104 Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease

Assante, G.; Chandrasekaran, S.; Ng, S.; Tourna, A.; Chung, C. H.; Isse, K. A.; Filippi, C.; Dhawan, A.; Liu, M.; Rozen, S. G.; Hoare, M.; Campbell, P.; Ballard, J. W. O.; Turner, N.; Morris, M. J.; Chokshi, S.; Youngson, N. A.

10.1101/2021.07.22.453333 — cancer biology — Posted on 2021-07-23

1105 Metabolism is the major driver of hydrogen isotope fractionation recorded in tree-ring glucose of Pinus nigra

Wieloch, T.; Grabner, M.; Augusti, A.; Serk, H.; Ehlers, I.; Yu, J.; Schleucher, J.

10.1101/2021.07.22.453377 — biophysics — Posted on 2021-07-23

1106 hafeZ: Active prophage identification through read mapping

Turkington, C. J. R.; Abadi, N. N.; Edwards, R. A.; Grasis, J. A.

10.1101/2021.07.21.453177 — bioinformatics — Posted on 2021-07-23

1107 High-throughput production of functional prototissues capable of producing NO for vasodilation

Zhang, X.; Li, C.; Liu, F.; Mu, W.; Ren, Y.; Yang, B.; Han, X.

10.1101/2021.07.22.453323 — bioengineering — Posted on 2021-07-23

1108 Herbarium specimens reveal herbivory patterns across the genus Cucurbita

Jenny, L. A.; Shapiro, L. R.; Davis, C. C.; Davies, T. J.; Pierce, N. E.; Meineke, E.

10.1101/2021.07.21.452357 — ecology — Posted on 2021-07-23

1109 Forest tree species composition and abiotic site conditions drive soil fungal communities and functional groups

Likulunga, L. E.; Rivera Pérez, C. A.; Schneider, D.; Daniel, R.; Polle, A.

10.1101/2021.07.21.453256 — ecology — Posted on 2021-07-23

1110 Untangling the ecological signal in the dental morphology in the bat superfamily Noctilionoidea

Lopez-Aguirre, C.; Hand, S.; Simmons, N. B.; Silcox, M.

10.1101/2021.07.21.453269 — ecology — Posted on 2021-07-23

1111 Cytolytic memory CD4+ T cell clonotypes are expanded during Plasmodium falciparum infection

Furtado, R.; Delahaye, F.; Zhang, J.; Sung, J.; Karell, P.; Kim, R. S.; Caillat-Zucman, S.; Liang, L.; Felgner, P.; Bauleni, A.; Gama, S.; Buchwald, A.; Taylor, T.; Seydel, K.; Laufer, M.; Daily, J.; Lauvau, G.

10.1101/2021.07.21.453277 — immunology — Posted on 2021-07-23

1112 Bassoon controls synaptic vesicle pools via regulation of presynaptic phosphorylation and cAMP homeostasis

Montenegro-Venegas, C.; Guhathakurta, D.; Pina-Fernandez, E.; Andres-Alonso, M.; Plattner, F.; Lazarevic, V.; Gundelfinger, E. D.; Fejtova, A.

10.1101/2021.07.22.453360 — neuroscience — Posted on 2021-07-23

1113 Individual difference in addiction-like behaviors and choice between cocaine versus food in Heterogeneous Stock rats

Sedighim, S.; Carrette, L. L.; Venniro, M.; Shaham, Y.; de Guglielmo, G.; George, O.

10.1101/2021.07.21.453270 — neuroscience — Posted on 2021-07-23

1114 Development of visual response selectivity in cortical GABAergic interneurons

Chang, J. T.; Fitzpatrick, D.

10.1101/2021.07.21.453281 — neuroscience — Posted on 2021-07-23

1115 Deep embeddings to comprehend and visualize microbiome protein space

Odrzywolek, K.; Karwowska, Z.; Majta, J.; Byrski, A.; Milanowska-Zabel, K.; Kosciolek, T.

10.1101/2021.07.21.452490 — bioinformatics — Posted on 2021-07-23

1116 Intra-Articular Delivery of an Indoleamine 2,3-Dioxygenase Galectin-3 Fusion Protein for Osteoarthritis Treatment in Male Lewis Rats

Partain, B. D.; Bracho-Sanchez, E.; Farhadi, S. A.; Yarmola, E. G.; Keselowsky, B. G.; Hudalla, G. A.; Allen, K. D.

10.1101/2021.07.21.453247 — bioengineering — Posted on 2021-07-23

1117 Fast and accurate bootstrap confidence limits on genome-scale phylogenies using little bootstraps

Sharma, S.; Kumar, S.

10.1101/2021.07.21.453255 — evolutionary biology — Posted on 2021-07-23

1118 The Amazon River microbiome, a story of humic carbon.

Sylvain, F.-E.; Bouslama, S.; Holland, A.; Leroux, N.; Mercier, P.-L.; Val, A. L.; Derome, N. J. A.

10.1101/2021.07.21.453257 — ecology — Posted on 2021-07-23

1119 Fast unconscious processing of emotional stimuli in early stages of the visual cortex

Carretie, L.; Fernandez-Folgueiras, U.; Alvarez, F.; Cipriani, G. A.; Tapia, M.; Kessel, D.

10.1101/2021.07.21.453248 — neuroscience — Posted on 2021-07-23

1120 Panx1b modulates the luminance response and direction of motion in the zebrafish

Safarian, N.; Houshangi-Tabrizi, S.; Zoidl, C.; Zoidl, G.

10.1101/2021.07.21.453251 — neuroscience — Posted on 2021-07-23

1121 Retrosplenial cortex is necessary for spatial and non-spatial latent learning in mice

Bottura de Barros, A. C.; Baruchin, L. J.; Panayi, M. C.; Nyberg, N.; Samborska, V.; Mealing, M. T.; Akam, T.; Kwag, J.; Bannerman, D. M.; Kohl, M. M.

10.1101/2021.07.21.453258 — neuroscience — Posted on 2021-07-23

1122 Transfer of learned cognitive flexibility to novel stimuli and task sets

Wen, T.; Geddert, R. M.; Madlon-Kay, S.; Egner, T.

10.1101/2021.07.21.453253 — neuroscience — Posted on 2021-07-23

1123 ELIMINATOR: Essentiality anaLysIs using MultIsystem Networks And inTeger prOgRamming

Antoranz, A.; Ortiz, M.; Pey, J.

10.1101/2021.07.21.453265 — bioinformatics — Posted on 2021-07-23

1124 No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing

Smits, N.; Rasmussen, J.; Bodea, G. O.; Amarilla, A. A.; Gerdes, P.; Sanchez-Luque, F. J.; Ajjikuttira, P.; Modhiran, N.; Liang, B.; Faivre, J.; Deveson, I. W.; Khromykh, A. A.; Watterson, D.; Ewing, A. D.; Faulkner, G. J.

10.1101/2021.05.28.446065 — genomics — Posted on 2021-07-23

1125 In-Vitro Fluorescence Microscopy Studies Show Retention of Spike-Protein (SARS-Cov-2) on Cell Membrane in the Presence of Amodiaquin Dihydrochloride Dihydrate Drug

Mondal, P. P.; Mandal, S.

10.1101/2021.01.05.424956 — biophysics — Posted on 2021-07-23

1126 Empirical single-cell tracking and cell-fate simulation reveal dual roles of p53 in tumor suppression

Rancourt, A.; Sato, S.; Satoh, M. S.

10.1101/319525 — cell biology — Posted on 2021-07-23

1127 The mRNA-LNP platform's lipid nanoparticle component used in preclinical vaccine studies is highly inflammatory

Ndeupen, S.; Qin, Z.; Jacobsen, S.; Estanbouli, H.; Bouteau, A.; Igyarto, B. Z.

10.1101/2021.03.04.430128 — immunology — Posted on 2021-07-23

1128 Representation learning for neural population activity with Neural Data Transformers

Ye, J.; Pandarinath, C.

10.1101/2021.01.16.426955 — neuroscience — Posted on 2021-07-23

1129 Raptor downregulation rescues neuronal phenotypes in mouse models of Tuberous Sclerosis Complex

Karalis, V.; Caval-Holme, F.; Bateup, H. S.

10.1101/2021.07.21.453275 — neuroscience — Posted on 2021-07-23

1130 Conserved exchange of paralog proteins during neuronal differentiation

Di Fraia, D.; Anitei, M.; Mackmull, M.-T.; Parca, L.; Behrendt, L.; Andres-Pons, A.; Gilmour, D.; Helmer-Citterich, M.; Kaether, C.; Beck, M.; Ori, A.

10.1101/2021.07.22.453347 — systems biology — Posted on 2021-07-23

1131 Capitalizing on paradoxical activation of the MAPK pathway for treatment of Imatinib-resistant mast cell leukemia and chronic myelogenous leukemia

Wilhelm, T.; Toledo, M. A.; Simons, I.; Stuth, C.; Mohta, V.; Mülfarth, R.; Nitsche, M.; Maschke-Neuss, K.; Schmitz, S.; Kaiser, A.; Arock, M.; Zenke, M.; Huber, M.

10.1101/2020.08.31.266734 — cancer biology — Posted on 2021-07-23

1132 Playing the piano with a robotic third thumb: Assessing constraints of human augmentation

Shafti, A.; Haar, S.; Mio Zaldivar, R.; Guilleminot, P.; Faisal, A. A.

10.1101/2020.05.21.108407 — neuroscience — Posted on 2021-07-23

1133 Trips and Neurotransmitters: Discovering Principled Patterns across 6,850 Hallucinogenic Experiences

Ballentine, G.; Friedman, S. F.; Bzdok, D.

10.1101/2021.07.13.452263 — neuroscience — Posted on 2021-07-23

1134 Flight-induced compass representation in the monarch butterfly heading network

Beetz, M. J.; Kraus, C.; Franzke, M.; Dreyer, D.; Strube-Bloss, M.; Roessler, W.; Warrant, E. J.; Merlin, C.; el Jundi, B.

10.1101/2021.04.07.438824 — neuroscience — Posted on 2021-07-23

1135 Modelling spinal locomotor circuits for movements in developing zebrafish

Roussel, Y.; Gaudreau, S. F.; Kacer, E. R.; Sengupta, M.; Bui, T. V.

10.1101/2021.02.10.430671 — neuroscience — Posted on 2021-07-23

1136 Different computations over the same inputs produce selective behavior in algorithmic brain networks

Jaworska, K.; van Rijsbergen, N. J.; Ince, R. A. A.; Schyns, P. G.

10.1101/2021.02.04.429372 — neuroscience — Posted on 2021-07-23

1137 A Hierarchy of Biomolecular Proportional-Integral-Derivative Feedback Controllers for Robust Perfect Adaptation and Dynamic Performance

Filo, M. G.; Khammash, M.

10.1101/2021.03.21.436342 — synthetic biology — Posted on 2021-07-23

1138 Binding of DNA origami to lipids: maximising yield and switching via strand-displacement

Singh, J. K. D.; Darley, E.; Ridone, P.; Gaston, J. P.; Abbas, A.; Wickham, S. F.; Baker, M. A.

10.1101/2020.06.01.128686 — biophysics — Posted on 2021-07-23

1139 Accurate model of liquid-liquid phase behaviour of intrinsically-disordered proteins from data-driven optimization of single-chain properties

Tesei, G.; Schulze, T. K.; Crehuet, R.; Lindorff-Larsen, K.

10.1101/2021.06.23.449550 — biophysics — Posted on 2021-07-23

1140 Bayesian model comparison for rare variant association studies

Venkataraman, G. R.; DeBoever, C.; Tanigawa, Y.; Aguirre, M.; Ioannidis, A. G.; Mostafavi, H.; Spencer, C. C. A.; Poterba, T.; Bustamante, C. D.; Daly, M. J.; Pirinen, M.; Rivas, M. A.

10.1101/257162 — genetics — Posted on 2021-07-23

1141 Fast transcriptional activation of developmental signalling pathways during wound healing of the calcareous sponge Sycon ciliatum

Caglar, C.; Ereskovsky, A.; Laplante, M.; Tokina, D.; Leininger, S.; Borisenko, I.; Aisbett, G.; Pan, D.; Adamski, M.; Adamska, M.

10.1101/2021.07.22.453456 — developmental biology — Posted on 2021-07-23

1142 Placental mitochondrial function, nutrient transporters, metabolic signalling and steroid metabolism relate to fetal size and sex in mice

Salazar-Petres, E.; Pereira Carvalho, D.; Lopez-Tello, J.; Sferruzzi-Perri, A.

10.1101/2021.07.22.453249 — developmental biology — Posted on 2021-07-23

1143 Age-related Cellular and Microstructural Changes in the Rotator Cuff Enthesis

Long, Z.; Nakagawa, K.; Wang, Z.; Amadio, P. C.; Zhao, C.; Gingery, A.

10.1101/2021.07.22.452068 — cell biology — Posted on 2021-07-23

1144 Matrix elasticity gradients guide neuronal polarity by controlling microtubule network mobility

Burute, M.; Jansen, K. I.; Mihajlovic, M.; Vermonden, T.; Kapitein, L.

10.1101/2021.07.22.453336 — cell biology — Posted on 2021-07-23

1145 De novo disease-associated mutations in KIF1A dominant negatively inhibit axonal transport of synaptic vesicle precursors

Anazawa, Y.; Kita, T.; Hayashi, K.; Niwa, S.

10.1101/2021.07.22.453457 — cell biology — Posted on 2021-07-23

1146 Manipulation of RNA Polymerase III by Herpes Simplex Virus-1

Dremel, S. E.; Sivrich, F. L.; Tucker, J. M.; Glaunsinger, B. A.; DeLuca, N. A.

10.1101/2021.07.21.453214 — molecular biology — Posted on 2021-07-23

1147 Chronic release of tailless phage particles from Lactococcus lactis

Liu, Y.; Alexeeva, S.; Bachmann, H.; Guerra Martinez, J. A.; Yeremenko, N.; Abee, T.; Smid, E. J.

10.1101/2021.07.21.453303 — microbiology — Posted on 2021-07-23

1148 A newly identified group of P-like (PL) fimbriae from extra-intestinal pathogenic Escherichia coli (ExPEC) encode distinct adhesin subunits and mediate adherence to host cells

Dozois, C. M.; Habouria, H.; Bessaiah, H.; Buron, J.; Houle, S.

10.1101/2021.07.20.453171 — microbiology — Posted on 2021-07-23

1149 Prediction of fluorophore brightness in designed mini fluorescence activating proteins

Hostetter, E. R.; Keyes, J. R.; Poon, I.; Nguyen, J. P.; Nite, J.; Molecular Modeling and Design Class, ; Jimenez Hoyos, C. A.; Smith, C. A.

10.1101/2021.07.21.452510 — biophysics — Posted on 2021-07-23

1150 Evaluation of feeding behaviour traits to predict efficiency traits in pigs using partial least square regression

Ewaoluwagbemiga, E. O.; Bee, G.; Kasper, C.

10.1101/2020.11.13.381103 — physiology — Posted on 2021-07-23

1151 Effects of non-invasive brain stimulation on visual perspective taking: A meta-analytic study

Yao, Y.-W.; Chopurian, V.; Zhang, L.; Lamm, C.; Heekeren, H. R.

10.1101/2021.04.24.441219 — neuroscience — Posted on 2021-07-23

1152 Learning the rules of collective cell migration using deep attention networks

LaChance, J.; Suh, K.; Cohen, D. J.

10.1101/2021.07.22.453371 — systems biology — Posted on 2021-07-22

1153 BioCRNpyler: Compiling Chemical Reaction Networks from Biomolecular Parts in Diverse Contexts

Poole, W.; Pandey, A.; Tuza, Z.; Shur, A.; Murray, R. M.

10.1101/2020.08.02.233478 — synthetic biology — Posted on 2021-07-23

1154 Evolution of Learning in Technology Adoption: The case of the U.S. Soybean Seed Industry.

Ilin, C.; Shi, G.

10.1101/2021.07.22.453433 — scientific communication and education — Posted on 2021-07-23

1155 Inferring a spatial code of cell-cell interactions across a whole animal body

Armingol, E.; Ghaddar, A.; Joshi, C. J.; Baghdassarian, H.; Shamie, I.; Chan, J.; Her, H.-L.; O'Rourke, E. J.; Lewis, N. E.

10.1101/2020.11.22.392217 — bioinformatics — Posted on 2021-07-23

1156 Ablation of Proliferating Osteoblast Lineage Cells After Fracture Leads to Atrophic Nonunion in a Mouse Model

Hixon, K. R.; McKenzie, J. A.; Sykes, D. A.; Yoneda, S.; Hensley, A.; Buettmann, E. G.; Zheng, H.; Skouteris, D.; McAlinden, A.; Miller, A. N.; Silva, M. J.

10.1101/2020.10.06.327288 — bioengineering — Posted on 2021-07-22

1157 Penalized Logistic Regression Analysis for Genetic Association Studies of Binary Phenotypes

Yu, Y.; Chen, S.; McNeney, B.

10.1101/2021.02.12.430986 — genetics — Posted on 2021-07-22

1158 The anterior Hox gene ceh-13 and elt-1/GATA activate the posterior Hox genes nob-1 and php-3 to specify posterior lineages in the C. elegans embryo

Murray, J. I.; Preston, E.; Crawford, J. P.; Rumley, J. D.; Amom, P.; Anderson, B. D.; Sivaramakrishnan, P.; Patel, S. D.; Bennett, B. A.; Lavon, T. D.; Peng, F.; Zacharias, A. L.

10.1101/2021.02.09.430385 — genetics — Posted on 2021-07-23

1159 Force generation of KIF1C is impaired by pathogenic mutations

Siddiqui, N.; Roth, D.; Toleikis, A.; Zwetsloot, A. J.; Cross, R. A.; Straube, A.

10.1101/2021.06.30.450611 — cell biology — Posted on 2021-07-23

1160 Local chromatin context dictates the genetic determinants of the heterochromatin spreading reaction

Greenstein, R. A.; Ng, H.; Barrales, R. R.; Tan, C.; Braun, S. J.; Al-Sady, B.

10.1101/2020.05.26.117143 — molecular biology — Posted on 2021-07-23

1161 TMT-based proteomic analysis of the antibiotic effects of ShangKeHuangShui against Straphylococcus aureus.

Liu, L.; Zhao, N.; Yang, K.; Liao, H.; Liu, X.; Wu, Y.; Lei, L.; Peng, X.; Wu, Y.

10.1101/2021.07.22.453437 — microbiology — Posted on 2021-07-22

1162 Perceiving and remembering speech depend on multifractal nonlinearity in movements producing and exploring speech

Bloomfield, L.; Lane, E.; Mangalam, M.; Kelty-Stephen, D.

10.1101/2021.03.28.437328 — neuroscience — Posted on 2021-07-22

1163 Bayesian mapping of the striatal microcircuit reveals robust asymmetries in the probabilities and distances of connections

Cinotti, F.; Humphries, M. D.

10.1101/2021.06.08.447507 — neuroscience — Posted on 2021-07-22

1164 Gene prioritization based on random walks with restarts and absorbing states, to define gene sets regulating drug pharmacodynamics from single-cell analyses

Sales-de-Queiroz, A.; Sales Santa Cruz, G.; Jean-Marie, A.; Mazauric, D.; Roux, J.; Cazals, F.

10.1101/2021.02.19.431974 — systems biology — Posted on 2021-07-22

1165 A pipeline for the reconstruction and evaluation of context-specific human metabolic models at a large-scale

Vieira, V.; Ferreira, J.; Rocha, M.

10.1101/2021.07.22.453372 — systems biology — Posted on 2021-07-22

1166 Numerical approaches for the rapid analysis of prophylactic efficacy against HIV with arbitrary drug-dosing schemes

Zhang, L.; Wang, J.; von Kleist, M.

10.1101/2021.07.22.453374 — systems biology — Posted on 2021-07-22

1167 Reconstruction of a generic genome-scale metabolic network for chicken: investigating network connectivity and finding potential biomarkers

Salehabadi, E.; Motamedian, E.; Shojaosadati, S. A.

10.1101/2021.07.22.453438 — systems biology — Posted on 2021-07-22

1168 Chemical inhibition of lycopene β-cyclases unmask operation of phytoene synthase 2 in ripening tomato fruits

Gupta, P.; Rodriguez-Franco, M.; Bodanapu, R.; Sreelakshmi, Y.; Sharma, R.

10.1101/2021.07.19.452896 — plant biology — Posted on 2021-07-22

1169 The beneficial effect of chronic muscular exercise on muscle fragility is increased by Prox1 gene transfer in dystrophic mdx muscle

Monceau, A.; Delacroix, C.; Lemaitre, M.; Revet, G.; Furling, D.; Agbulut, O.; Klein, A.; Ferry, A.

10.1101/2021.07.22.453435 — physiology — Posted on 2021-07-22

1170 GIV/Girdin binds BRCA1 and links trimeric G-proteins to DNA damage response

Abd El-Hafeez, A. A.; Sun, N.; Chakraborty, A.; Ear, J.; Roy, S.; Chamarthi, P.; Rajapakse, N.; Das, S.; Luker, K. E.; Hazra, T. K.; Luker, G. D.; Ghosh, P.

10.1101/2021.07.21.452842 — cancer biology — Posted on 2021-07-22

1171 Perturbation of BRMS1 interactome reveals pathways that impact cell migration

Zimmermann, R. C.; Sardiu, M. E.; Manton, C. A.; Miah, M. S.; Banks, C. A.; Adams, M. K.; Koestler, D. C.; Hurst, D. R.; Edmonds, M. D.; Washburn, M. P.; Welch, D. R.

10.1101/2021.02.04.429764 — cancer biology — Posted on 2021-07-22

1172 Genomic context sensitivity of insulator function

Ribeiro-dos-Santos, A. M.; Hogan, M. S.; Luther, R.; Maurano, M. T.

10.1101/2021.05.16.444030 — genomics — Posted on 2021-07-22

1173 Transcription factor regulation of eQTL activity across individuals and tissues

Flynn, E.; Tsu, A. L.; Kasela, S.; Kim-Hellmuth, S.; Aguet, F.; Ardlie, K. G.; Bussemaker, H. J.; Mohammadi, P.; Lappalainen, T.

10.1101/2021.07.20.453075 — genomics — Posted on 2021-07-22

1174 A modified fluctuation assay reveals a natural mutator phenotype that drives mutation spectrum variation within Saccharomyces cerevisiae

Jiang, P.; Ollodart, A. R.; Sudhesh, V.; Herr, A. J.; Dunham, M. J.; Harris, K.

10.1101/2021.01.11.425955 — evolutionary biology — Posted on 2021-07-22

1175 Entrainment of Endangered Sturgeon by a Large Water Diversion: Rescue, Enumeration, and Conservation Opportunities

Killgore, K. J.; Hoover, J. J.; Slack, W. T.; George, S. G.; Brantley, C. G.

10.1101/2021.07.22.453439 — ecology — Posted on 2021-07-22

1176 Optimal strategy for public good production is set by balancing intertemporal trade-off between population growth rate and carrying capacity

Gangan, M. S.; Vasconcelos, M. M.; Mitra, U.; Camara, O.; Boedicker, J. Q.

10.1101/2021.07.22.453373 — microbiology — Posted on 2021-07-22

1177 MERTK on mononuclear phagocytes regulates T cell antigen recognition at autoimmune and tumor sites

Lindsay, R. S.; Whitesell, J. C.; Dew, K. E.; Rodriguez, E.; Sandor, A. M.; Tracy, D.; Yannacone, S. F.; Basta, B. N.; Jacobelli, J.; Friedman, R. S.

10.1101/687061 — immunology — Posted on 2021-07-22

1178 Forearm and hand muscles exhibit high coactivation and overlapping of cortical motor representations

Pazin Tardelli, G.; Souza, V. H.; Hiroshi Matsuda, R.; Cavalcanti Garcia, M. A.; Novikov, P.; Nazarova, M.; Baffa, O.

10.1101/2021.07.20.453121 — neuroscience — Posted on 2021-07-22

1179 Comprehensive Phenotyping of Cutaneous Afferents Reveals Rapid-Onset Alterations in Nociceptor Response Properties Following Spinal Cord Injury

Eller, O. C.; Stair, R. N.; Nelson-Brantley, J.; Young, E. E.; Baumbauer, K. M.

10.1101/2021.06.15.448577 — neuroscience — Posted on 2021-07-22

1180 GABAA and NMDA receptor density alterations and their behavioral correlates in the gestational methylazoxymethanol acetate model for schizophrenia

Kiemes, A.; Gomes, F. V.; Cash, D.; Uliana, D. L.; Simmons, C.; Singh, N.; Vernon, A. C.; Turkheimer, F. E.; Davies, C.; Stone, J. M.; Grace, A. A.; Modinos, G.

10.1101/2021.06.21.449343 — neuroscience — Posted on 2021-07-22

1181 Metabolic-sensing in AgRP neurons integrates homeostatic state with dopamine signalling in the striatum

Reichenbach, A.; Clarke, R.; Stark, R.; Lockie, S. H.; Mequinion, M.; Reed, F.; Rawlinson, S.; Dempsey, H.; Sepehrizadeh, T.; DeVeer, M.; Munder, A. C.; Nunez-Iglesias, J.; Spanswick, D. C.; Mynatt, R.; Kravitz, L.; Dayas, C. V.; Brown, R.; Andrews, Z. B.

10.1101/2021.03.22.436393 — neuroscience — Posted on 2021-07-22

1182 Image-based assessment of plant disease progression identifies new genetic loci for resistance

Meline, V.; Caldwell, D.; Kim, B.-S. S.; Baireddy, S.; Yang, C.; Sparks, E. E.; Delp, E. J.; Iyer-Pascuzzi, A. S.

10.1101/2021.07.13.452064 — plant biology — Posted on 2021-07-22

1183 The framework of plant regeneration in duckweed (Lemna turonifera) comprises genetic transcript regulation and cyclohexane release

Yang, L.; Sun, J.; Yao, J.; Wang, Y.; Yan, C.; Wu, J.; Ren, Q.; Zhao, L.; Sun, J.

10.1101/2021.07.22.453434 — plant biology — Posted on 2021-07-22

1184 Wilson Statistics: Derivation, Generalization, and Applications to Electron Cryomicroscopy

Singer, A.

10.1101/2021.05.14.444177 — biophysics — Posted on 2021-07-22

1185 Integrating long-range regulatory interactions to predict gene expression using graph convolutional networks

Bigness, J.; Loinaz, X.; Patel, S.; Larschan, E.; Singh, R.

10.1101/2020.11.23.394478 — bioinformatics — Posted on 2021-07-22

1186 Causal inference using deep-learning variable selection identifies and incorporates direct and indirect causalities in complex biological systems

Fan, Z.; Kernan, K. F.; Benos, P. V.; Canna, S. W.; Carcillo, J. A.; Kim, S.; Park, H. J.

10.1101/2021.07.17.452800 — bioinformatics — Posted on 2021-07-22

1187 Electronic "photoreceptors" enable prosthetic vision with acuity matching the natural resolution in rats

Wang, B.-Y.; Chen, Z. C.; Bhuckory, M.; Huang, T. W.; Shin, A.; Zuckerman, V.; Ho, E.; Rosenfeld, E.; Galambos, L.; Kamins, T.; Mathieson, K.; Palanker, D.

10.1101/2021.07.12.452093 — bioengineering — Posted on 2021-07-22

1188 A stable pollination environment limits current but not potential evolution of floral traits

Castellanos, M. C.; Montero-Pau, J.; Ziarsolo, P.; Blanca, J. M.; Canizares, J.; Pausas, J. G.

10.1101/581827 — evolutionary biology — Posted on 2021-07-22

1189 Social-like responses are inducible in asocial Mexican cavefish despite the exhibition of strong repetitive behaviour

Iwashita, M.; Yoshizawa, M.

10.1101/2020.08.20.258640 — evolutionary biology — Posted on 2021-07-22

1190 A variable-rate quantitative trait evolution model using penalized-likelihood

Revell, L. J.

10.1101/2021.04.17.440282 — evolutionary biology — Posted on 2021-07-22

1191 Parallel genetic changes underlie integrated craniofacial traits in an adaptive radiation of trophic specialist pupfishes

St John, M. E.; Dunker, J. C.; Richards, E.; Romero, S.; Martin, C. H.

10.1101/2021.07.01.450661 — evolutionary biology — Posted on 2021-07-22

1192 Origin and evolutionary landscape of Nr2f transcription factors across Metazoa

Coppola, U.; Waxman, J. S.

10.1101/2021.07.22.453436 — evolutionary biology — Posted on 2021-07-22

1193 Restructuring of genomic provinces of surface ocean plankton under climate change

Fremont, P.; Gehlen, M.; Vrac, M.; Leconte, J.; Delmont, T.; Wincker, P.; Iudicone, D.; Jaillon, O.

10.1101/2020.10.20.347237 — ecology — Posted on 2021-07-22

1194 Histone acetyltransferase activity of CREB-binding protein is essential for synaptic plasticity in Lymnaea

Hatakeyama, D.; Sunada, H.; Totani, Y.; Watanabe, T.; Felletar, I.; Fitchett, A.; Eravci, M.; Anagnostopoulou, A.; Miki, R.; Kuzuhara, T.; Kemenes, I.; Ito, E.; Kemenes, G.

10.1101/2021.05.26.445902 — neuroscience — Posted on 2021-07-22

1195 Structure and lipid-mediated remodelling mechanism of the Na+/H+ exchanger NHA2

Matsuoka, R.; Fudim, R.; Jung, S.; Zhang, C.; Bazzone, A.; Chatzikyriakidou, Y.; Nomura, N.; Iwata, S.; Orellana, L.; Beckstein, O.; Drew, D.

10.1101/2021.07.22.453398 — biophysics — Posted on 2021-07-22

1196 Insertion sequences associated with antibiotic resistance genes in Enterococcus isolates from an inpatient with prolonged bacteremia.

Udaondo, Z.; Abram, K. Z.; Kothari, A.; Jun, S.-R.

10.1101/2021.07.22.453447 — genomics — Posted on 2021-07-22

1197 Limited accessibility of nitrogen supplied as amino acids, amides, and amines as energy sources for marine Thaumarchaeota

Damashek, J.; Bayer, B.; Herndl, G. J.; Wallsgrove, N. J.; Allen, T.; Popp, B. N.; Hollibaugh, J. T.

10.1101/2021.07.22.453390 — microbiology — Posted on 2021-07-22

1198 Cryo-EM structure of the NLRP3 decamer bound to the cytokine release inhibitory drug CRID3

Hochheiser, I. V.; Pilsl, M.; Hagelueken, G.; Moecking, J.; Marleaux, M.; Brinkschulte, R.; Latz, E.; Engel, C.; Geyer, M.

10.1101/2021.07.22.453353 — immunology — Posted on 2021-07-22

1199 Transcriptional regulatory features associated with Coccidioides immitis phase transition

Duttke, S. H.; Beyhan, S.; Singh, R.; Neal, S. E.; Viriyakosol, S.; Fierer, J.; Kirkland, T. N.; Stajich, J. E.; Benner, C.; Carlin, A.

10.1101/2021.07.22.453417 — immunology — Posted on 2021-07-22

1200 Binocular Benefit Following Monocular Subretinal AAV Injection in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa (adRP)

Ahmed, C. M.; Massengill, M. T.; Ildefonso, C. J.; Zhu, P.; Li, H.; Patel, A. P.; Lewin, A. S.

10.1101/2021.07.22.453413 — neuroscience — Posted on 2021-07-22

1201 Fructose appetition in "taste-blind" P2X2/P2X3 double knockout mice

Sclafani, A.; Ackroff, K.

10.1101/2021.07.22.453428 — neuroscience — Posted on 2021-07-22

1202 Gestational insulin resistance is mediated by the gut microbiome-indoleamine 2,3-dioxygenase axis

Priyadarshini, M.; Navarro, G.; Reiman, D.; Sharma, A.; Xu, K.; Lednovich, K.; Manzella, C. R.; Khan, M. W.; Wicksteed, B.; Chlipala, G. E.; Szynal, B.; Bernabe, B. P.; Maki, P. M.; Gill, R. K.; Gilbert, J.; Dai, Y.; Layden, B. T.

10.1101/2021.07.21.453234 — physiology — Posted on 2021-07-22

1203 GIV/Girdin binds BRCA1 and links trimeric G-proteins to DNA damage response

Abd El-Hafeez, A. A.; Sun, N.; Chakraborty, A.; Ear, J.; Roy, S.; Chamarthi, P.; Rajapakse, N.; Das, S.; Luker, K. E.; Hazra, T. K.; Luker, G. D.; Ghosh, P.

10.1101/2021.07.21.452842 — cancer biology — Posted on 2021-07-22

1204 Unitary Structure of Palindromes in DNA

Tibatan, M. A.; Sarisaman, M.

10.1101/2021.07.21.453288 — biophysics — Posted on 2021-07-22

1205 GM1 mediates the formation and maintenance of cytotoxic Aβ oligomers

Zhang, D.; Wang, J.; Fleeman, R. M.; Kuhn, M. K.; Swulius, M. T.; Proctor, E. A.; Dokholyan, N. V.

10.1101/2021.07.22.453392 — biophysics — Posted on 2021-07-22

1206 Conformation and membrane interaction studies of the potent antimicrobial and anticancer peptide palustrin-Ca

Timmons, P. B.; Hewage, C. M.

10.1101/2021.07.22.453375 — biochemistry — Posted on 2021-07-22

1207 E-cadherin regulates the stability and transcriptional activity of β-catenin in embryonic stem cells

Bhattacharyya, S.; Mote, R. D.; Freimer, J.; Singh, S. B.; Arumugam, S.; Narayana, Y. V.; Rajan, R.; Subramanyam, D.

10.1101/2021.07.22.453344 — cell biology — Posted on 2021-07-22

1208 Systematic mapping of small nucleolar RNA targets in human cells

Dunn-Davies, H.; Dudnakova, T.; Langhendries, J.-L.; Watkins, N.; Lafontaine, D. L.; Tollervey, D.

10.1101/2021.07.22.451324 — cell biology — Posted on 2021-07-22

1209 Csp1, A Cold-Shock Protein Homolog in Xylella fastidiosa Influences Pili Formation, Stress Response, and Gene Expression

Wei, W.; Burbank, L. P.; Sawyer, T.

10.1101/2021.07.21.453299 — molecular biology — Posted on 2021-07-22

1210 Characterization of early Alzheimer's-like pathological alterations in non-human primates with aging: a pilot study

Jester, H.; Gosrani, S.; Ding, H.; Zhou, X.; Ko, M.-C.; Ma, T.

10.1101/2021.07.21.453246 — molecular biology — Posted on 2021-07-22

1211 PICH, an ATP-dependent chromatin remodeling protein, transcriptionally co-regulates oxidative stress response.

Dutta, A.; Das, A.; Bisht, D.; Arya, V.; Muthuswami, R.

10.1101/2021.07.21.453306 — molecular biology — Posted on 2021-07-22

1212 RTT109 AND Fun30 proteins mediate epigenetic regulation of the DNA damage response pathway in C. albicans

Maurya, P. K.; Garai, P.; Goel, K.; Bhatt, H.; Goyal, A.; Dewasthale, S.; Gupta, M.; Dutta, A.; Haokip, D. T.; Barik, S.; Muthuswami, R.

10.1101/2021.07.22.453354 — molecular biology — Posted on 2021-07-22

1213 Quantification of archaea-driven freshwater nitrification: from single cell to ecosystem level

Klotz, F.; Kitzinger, K.; Ngugi, D. K.; Buesing, P.; Littmann, S.; Kuypers, M. M. M.; Schink, B.; Pester, M.

10.1101/2021.07.22.453385 — microbiology — Posted on 2021-07-22

1214 Roles of proteins containing immunoglobulin-like domains in the conjugation of bacterial plasmids.

Huttener, M.; Hergueta, J.; Bernabeu, M.; Prieto, A.; Aznar, S.; Merino, S.; Tomas, J.; Juarez, A.

10.1101/2021.07.22.453378 — microbiology — Posted on 2021-07-22

1215 The Murine Neuronal Receptor NgR1 Is Dispensable for Reovirus Pathogenesis

Aravamudhan, P.; Guzman-Cardozo, C.; Urbanek, K.; Welsh, O.; Konopka-Anstadt, J.; Sutherland, D. M.; Dermody, T. S.

10.1101/2021.07.22.453368 — microbiology — Posted on 2021-07-22

1216 Gammaherpesvirus infection licenses age-associated B cells for pathogenicity in MS and EAE

Mouat, I. C.; Allanach, J. R.; Fan, V.; Girard, A. M.; Shanina, I.; Vorobeychik, G.; Horwitz, M. S.

10.1101/2021.07.22.453263 — immunology — Posted on 2021-07-22

1217 CYP1B1 converts procarcinogens into genotoxins in Saccharomyces cerevisiae

Fasullo, M.; Perpetua, N.; Kannan, A.; Dolan, M.

10.1101/2021.07.22.453414 — pharmacology and toxicology — Posted on 2021-07-22

1218 Assessing target engagement using proteome-wide solvent shift assays

Van Vranken, J. G.; Li, J.; Navarrete Perea, J.; Gygi, S. P.

10.1101/2021.07.22.453338 — biochemistry — Posted on 2021-07-22

1219 Proton-mediated gating mechanism of anion channelrhodopsin-1

Tsujimura, M.; Kojima, K.; Kawanishi, S.; Sudo, Y.; Ishikita, H.

10.1101/2021.07.22.453395 — biochemistry — Posted on 2021-07-22

1220 Impacts of Fluorescent Base Analogue Substitution on the Folding of a Riboswitch

Hoeher, J. E.; Veirs, M. A.; Widom, J. R.

10.1101/2021.07.22.453416 — biochemistry — Posted on 2021-07-22

1221 Dichloroacetate improves systemic energy balance and feeding behavior during sepsis

Oh, T.; Zabalawi, M.; Jain, S.; Long, D.; Stacpoole, P.; McCall, C.; Quinn, M. A.

10.1101/2021.07.21.453238 — immunology — Posted on 2021-07-22

1222 CD8+ T cell signature in acute SARS-CoV-2 infection identifies memory precursors

Adamo, S.; Michler, J.; Zurbuchen, Y.; Cervia, C.; Taeschler, P.; Raeber, M. E.; Baghai Sain, S.; Nilsson, J.; Moor, A.; Boyman, O.

10.1101/2021.07.22.453029 — immunology — Posted on 2021-07-22

1223 Abnormal Recovery from Acute Stress in Huntingtons Disease Mice

Zacharoff, L. A.; Hamid, A. A.; Engeland, W. C.; Dubinsky, J. M.

10.1101/2021.07.21.453245 — neuroscience — Posted on 2021-07-22

1224 Gastrodia-Uncaria Water Extract Inhibits Endoplasmic Reticulum Stress and Matrix Metalloproteinase in Protecting against Cerebral Ischemia

Choi, A. Y.; Xian, J. W.; Ma, S. Y.; Lin, Z.; Chan, C. W.

10.1101/2021.07.21.452303 — neuroscience — Posted on 2021-07-22

1225 Automated imaging of duckweed growth and development

Cox, K. L.; Manchego, J.; Meyers, B. C.; Czymmek, K. J.; Harkess, A.

10.1101/2021.07.21.453240 — plant biology — Posted on 2021-07-22

1226 NetSolP: predicting protein solubility in E. coli using language models

Thumuluri, V.; Martiny, H.-M.; Armenteros, J. J. A.; Salomon, J.; Nielsen, H.; Johansen, A.

10.1101/2021.07.21.453084 — bioinformatics — Posted on 2021-07-22

1227 Democratizing Data-Independent Acquisition Proteomics Analysis on Public Cloud Infrastructures Via The Galaxy Framework

Fahrner, M.; Foell, M. C.; Gruening, B.; Bernt, M.; Rost, H.; Schilling, O.

10.1101/2021.07.21.453197 — bioinformatics — Posted on 2021-07-22

1228 Competent immune responses to SARS-CoV-2 variants in older adults following mRNA vaccination

Jergovic, M.; Uhrlaub, J. L.; Watanabe, M.; Bradshaw, C. M.; White, L. M.; LaFleur, B. J.; Edwards, T.; Sprissler, R.; Worobey, M.; Bhattacharya, D.; Nikolich-Zugich, J.

10.1101/2021.07.22.453287 — immunology — Posted on 2021-07-22

1229 Optical manipulations reveal strong reciprocal inhibition but limited recurrent excitation within olfactory bulb glomeruli

Zak, J. D.; Schoppa, N. E.

10.1101/2021.07.21.453150 — neuroscience — Posted on 2021-07-22

1230 Patterns of gene co-expression under water-deficit treatments and pan-genome occupancy in Brachypodium distachyon.

Sancho, R.; Catalan, P.; Contreras-Moreira, B.; Juenger, T.; Des Marais, D. L.

10.1101/2021.07.21.453242 — plant biology — Posted on 2021-07-22

1231 Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer

Memon, D.; Rizvi, H.; Fromm, G.; Lihm, J.; Schoenfeld, A. J.; Sauter, J. L.; Luo, J.; Chow, A.; Bhanot, U. K.; McCarthy, C.; Ye, D.; Vanderbilt, C. M.; Liu, C.; Abu-Akeel, M.; Plodkowski, A. J.; McGranahan, N.; Luksza, M.; Greenbaum, B. D.; Merghoub, T.; Minn, A. J.; Beltrao, P.; Schreiber, T. H.; Miller, M. L.; Hellmann, M. D.

10.1101/2021.07.21.452854 — cancer biology — Posted on 2021-07-22

1232 Structure insights, thermodynamic profiles, dsDNA melting activity, and liquid-liquid phase separation of the SARS-CoV-2 nucleocapsid N-terminal domain binding to DNA

Caruso, I. P.; Almeida, V. S.; Amaral, M. J.; Andrade, G. C.; Araujo, G. R.; Araujo, T. S.; Azevedo, J. M.; Barbosa, G. M.; Bartkevihi, L.; Bezerra, P. R.; Cabral, K. M. d. S.; Lourenco, I. O.; Malizia-Motta, C. L. F.; Marques, A. L.; Mebus-Antunes, N. C.; Neves-Martins, T. C.; de Sa, J. M.; Sanches, K.; Santana-Silva, M. C.; Vasconcelos, A. A.; Almeida, M. S.; Amorim, G. C.; Anobom, C. D.; Da Poian, A. T.; Gomes-Neto, F.; Pinheiro, A. S.; Almeida, F. C. L.

10.1101/2021.07.21.453232 — biophysics — Posted on 2021-07-22

1233 Evolutionary tuning of a key helix drove androgen selectivity

Okafor, C. D.; Colucci, J. K.; Cato, M. L.; Khan, S. H.; Cottrill, K.; Hercules, D.; Eick, G.; Thornton, J. W.; Ortlund, E. A.

10.1101/2021.07.21.453223 — evolutionary biology — Posted on 2021-07-22

1234 ADAR mediated A-to-I RNA editing affects SARS-CoV-2 characteristics and fuels its evolution

Song, Y.; He, X.; Yang, W.; Tang, T.; Zhang, R.

10.1101/2021.07.22.453345 — microbiology — Posted on 2021-07-22

1235 Neuroprotective, antioxidant and antiproliferative activity of grapefruit IntegroPectin on SH-SY5Y cells

Nuzzo, D.; Scodino, M.; Scurria, A.; Giardina, C.; Giordano, F.; Meneguzzo, F.; Mudo, G.; Pagliaro, M.; Picone, P.; Attanzio, A.; Raimondo, S.; Ciriminna, R.; Di Liberto, V.

10.1101/2021.07.21.453202 — neuroscience — Posted on 2021-07-22

1236 The five Urochola spp. used in development of tropical forage cultivars originate from defined subpopulations with differentiated gene pools

Higgins, J.; Tomaszewska, P.; Pellny, T. K.; Castiblanco, V.; Arango, J.; Tohme, J.; Schwarzacher, T.; Mitchell, R.; Heslop-Harrison, J. S.; De Vega, J. J.

10.1101/2021.07.21.453213 — plant biology — Posted on 2021-07-22

1237 Kinome state is predictive of cell viability in pancreatic cancer tumor and stroma cell lines

Berginski, M. E.; Jenner, M. R.; Joisa, C. U.; Herrera Loeza, S. G.; Golitz, B. T.; Lipner, M. B.; Leary, J. R.; Rashid, N. U.; Johnson, G. L.; Yeh, J. J.; Gomez, S. M.

10.1101/2021.07.21.451515 — bioinformatics — Posted on 2021-07-22

1238 CoverageMaster: comprehensive CNV detection and visualization from NGS short reads for genetic medicine applications

Rapti, M.; Meylan Merlini, J.; Ranza, E.; Antonarakis, S. E.; Santoni, F. A.

10.1101/2021.07.21.453195 — bioinformatics — Posted on 2021-07-22

1239 skater: An R package for SNP-based Kinship Analysis, Testing, and Evaluation

Turner, S. D.; Nagraj, V. P.; Scholz, M.; Jessa, S.; Acevedo, C.; Ge, J.; Woerner, A. E.; Budowle, B.

10.1101/2021.07.21.453083 — bioinformatics — Posted on 2021-07-22

1240 Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes

Schunkert, H.; Li, L.; Chen, Z.; Scheidt, M. v.; Steiner, A.; Gueldener, U.; Koplev, S.; Ma, A.; Hao, K.; Pan, C.; Lusis, A. J.; Pang, S.; Kessler, T.; Ermel, R.; Sukhavasi, K.; Ruusalepp, A.; Gagneur, J.; Erdmann, J.; Kovacic, J. C.; Bjoerkegren, J. L. M.

10.1101/2021.07.21.453208 — genetics — Posted on 2021-07-22

1241 The infinite alleles model revisited: a Gibbs sampling approach

Manceau, M.

10.1101/2021.07.21.452479 — evolutionary biology — Posted on 2021-07-22

1242 Lowland plant migrations into alpine ecosystems amplify soil carbon loss under climate warming

Walker, T. W. N.; Gavazov, K.; Guillaume, T.; Lambert, T.; Mariotte, P.; Routh, D.; Signarbieux, C.; Block, S.; Muenkemueller, T.; Nomoto, H.; Crowther, T. W.; Richter, A.; Buttler, A.; Alexander, J. M.

10.1101/2021.07.21.453211 — ecology — Posted on 2021-07-22

1243 Multiple stressor null models frequently fail to detect most interactions due to low statistical power

Burgess, B. J.; Jackson, M. C.; Murrell, D. J.

10.1101/2021.07.21.453207 — ecology — Posted on 2021-07-22

1244 Functional similarity, not phylogenetic relatedness, predicts the relative strength of competition

Mahon, M. B.; Jennings, D. E.; Civitello, D. J.; Lajeunesse, M. J.; Rohr, J. R.

10.1101/2021.07.21.453226 — ecology — Posted on 2021-07-22

1245 Transgenesis in the acoel Hofstenia miamia

Ricci, L.; Srivastava, M.

10.1101/2021.07.21.453044 — developmental biology — Posted on 2021-07-22

1246 Impact of human airway epithelial cellular composition on SARS-CoV-2 infection biology

Wang, Y.; Thaler, M.; Ninaber, D.; van der Does, A. M.; S. Ogando, N. S.; Beckert, H.; Taube, C.; Salgado Benvindo Da Silva, C.; Snijder, E. J.; Bredenbeek, P. J.; Hiemstra, P.; van Hemert, M. J.

10.1101/2021.07.21.453304 — cell biology — Posted on 2021-07-22

1247 Conserved Circuits for Direction Selectivity in the Primate Retina

Patterson, S. S.; Bembry, B. N.; Mazzaferri, M. A.; Neitz, M.; Rieke, F.; Soetedjo, R.; Neitz, J.

10.1101/2021.07.21.453225 — neuroscience — Posted on 2021-07-22

1248 Shaping nanoparticle diffusion through biological barriers to drug delivery

Lee, B. J.; Cheema, Y.; Bader, S.; Duncan, G. A.

10.1101/2021.07.21.453209 — bioengineering — Posted on 2021-07-22

1249 Expression patterns of Arc mRNA after renewal of appetitive behavior in female rats.

Hilz, E. N.; Agee, L. A.; Jun, D. S.; Monfils, M. H.; Lee, H. J.

10.1101/2021.07.20.453088 — animal behavior and cognition — Posted on 2021-07-22

1250 Novel Generic Models for Differentiating Stem Cells Reveal Oscillatory Mechanisms

Farjami, S.; Camargo Sosa, K.; Dawes, J. H. P.; Kelsh, R. N.; Rocco, A.

10.1101/2021.05.28.446119 — developmental biology — Posted on 2021-07-22

1251 Fixation probabilities in network structuredmeta-populations

Yagoobi, S.; Traulsen, A.

10.1101/2021.07.21.453198 — evolutionary biology — Posted on 2021-07-22

1252 Contribution of genome scale metabolic modeling to niche theory

Regimbeau, A.; Budinich, M.; Larhlimi, A.; Pierella Karlusich, J. J.; Aumont, O.; Memery, L.; Bowler, C.; Eveillard, D.

10.1101/2021.07.21.453190 — ecology — Posted on 2021-07-22

1253 Hypoxia induces a transcriptional early primitive streak signature in pluripotent cells enhancing spontaneous elongation and lineage representation in gastruloids

Lopez-Anguita, N.; Gassaloglu, S. I.; Stötzel, M.; Typou, M.; Virta, I.; Hetzel, S.; Buschow, R.; Koksal, B.; Atilla, D.; Maitschke-Rajasekharan, R.; Chen, R.; Mattei, A. L.; Bedzhov, I.; Meierhofer, D.; Meissner, A.; Veenvliet, J. V.; Bulut-Karslioglu, A.

10.1101/2021.07.21.452906 — developmental biology — Posted on 2021-07-22

1254 Spatial and Temporal Organization of Composite Receptive Fields in the Songbird Auditory Forebrain

Vahidi, N. W.

10.1101/2021.07.21.453115 — neuroscience — Posted on 2021-07-22

1255 Lineage-specific regulatory changes in the pathological cardiac remodeling of hypertrophy cardiomyopathy unraveled by single-nucleus RNA-seq and spatial transcriptomics

Liu, X.; Yin, K.; Chen, L.; Chen, W.; Li, W.; Zhang, T.; Sun, Y.; Yuan, M.; Wang, H.; Wang, S.; Hu, S.; Zhou, Z.

10.1101/2021.07.21.453191 — pathology — Posted on 2021-07-22

1256 Egg size variation in a long-lived polyandrous shorebird in the context of senescence and breeding phenology

Eberhart-Hertel, L. J.; Falcao Rodrigues, L.; Krietsch, J.; Eberhart-Hertel, A. G.; Cruz-Lopez, M.; Vazquez-Rojas, K. A.; Gonzalez-Medina, E.; Schroeder, J.; Kuepper, C.

10.1101/2021.07.21.453188 — evolutionary biology — Posted on 2021-07-22

1257 Probing remdesivir nucleotide analogue insertion to SARS-CoV-2 RNA dependent RNA polymerase in viral replication

Romero, M. E.; Long, C.; La Rocco, D.; Keerthi, A. M.; Xu, D.; Yu, J.

10.1101/2021.07.12.452099 — biophysics — Posted on 2021-07-22

1258 Testing the accuracy of 3D automatic landmarking via genome-wide association studies

Savriama, Y.; Tautz, D.

10.1101/2021.07.22.453315 — genomics — Posted on 2021-07-22

1259 TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling

Sivakumar, S.; Qi, S.; Cheng, N.; sathe, A. a.; Kanchwala, M.; Kumar, A.; Evers, B. M.; Xing, C.; Yu, H.

10.1101/2021.07.22.453348 — developmental biology — Posted on 2021-07-22

1260 Evolutionary conservation of centriole rotational asymmetry in the human centrosome

GAUDIN, N.; MARTIN GIL, P.; BOUMENDJEL, M.; ERSHOV, D.; PIOCHE-DURIEU, C.; BOUIX, M.; DELOBELLE, Q.; MANISCALCO, L.; PHAN, T. B. N.; HEYER, V.; REINA-SAN-MARTIN, B.; AZIMZADEH, J.

10.1101/2021.07.21.453218 — cell biology — Posted on 2021-07-22

1261 Developmental landscape of human forebrain at a single-cell level unveils early waves of oligodendrogenesis

van Bruggen, D.; Pohl, F. B.; Mattsson Langseth, C.; Kukanja, P.; Lee, H.; Kabbe, M.; Meijer, M.; Hilscher, M.; Nilsson, M.; Sundstrom, E.; Castelo-Branco, G.

10.1101/2021.07.22.453317 — neuroscience — Posted on 2021-07-22

1262 Synergistic regulation of bZIP53 and dimerizing partners results in abnormal seed phenotype in Arabidopsis: Use of a designed dominant negative protein A-ZIP53

Jain, P.; Rishi, V.

10.1101/2021.07.20.453159 — plant biology — Posted on 2021-07-22

1263 Transcriptional and Post-transcriptional Regulation of Ethylene Biosynthesis by Salicyclic Acid in Kiwifruit

Wang, J.; Liu, X.; Wang, W.-q.; Zhang, H.-q.; Yin, X.-r.

10.1101/2021.07.19.452972 — plant biology — Posted on 2021-07-22

1264 High potency of sequential therapy with only beta-lactam antibiotics

Batra, A.; Roemhild, R.; Rousseau, E.; Franzenburg, S.; Niemann, S.; Schulenburg, H.

10.1101/2021.07.20.453050 — evolutionary biology — Posted on 2021-07-22

1265 Forward planning driven by context-dependent conflict processing in anterior cingulate cortex

Ott, F.; Kiebel, S.; Legler, E.

10.1101/2021.07.19.452905 — neuroscience — Posted on 2021-07-22

1266 Data-driven causal analysis of observational time series in ecology

Yuan, A. E.; Shou, W.

10.1101/2020.08.03.233692 — bioinformatics — Posted on 2021-07-22

1267 Bayesian inference of population prevalence

Ince, R. A. A.; Paton, A. T.; Kay, J. W.; Schyns, P. G.

10.1101/2020.07.08.191106 — neuroscience — Posted on 2021-07-22

1268 Fine-scale quantification of GC-biased gene conversion intensity in mammals.

Galtier, N.

10.1101/2021.05.05.442789 — evolutionary biology — Posted on 2021-07-22

1269 Direct programming of human mammary self-organised organoids by miR-106a-3p

Delom, F.; Puceat, M.; Fessart, D.

10.1101/314658 — cell biology — Posted on 2021-07-22

1270 Single-cell transcriptomic resolution of stem cells and their developmental trajectories in the hippocampus reveals epigenetic control of cell state perseverance

Salas-Bastos, A.; Treppner, M.; Herman, J. S.; Koutsogiannis, D.; Binder, H.; Stadler, M. B.; Grün, D.; Vogel, T.

10.1101/2021.07.21.452775 — neuroscience — Posted on 2021-07-22

1271 Developmental stage-specific patterned activity contributes to callosal axon projections

Tezuka, Y.; Hagihara, K. M.; Ohki, K.; Hirano, T.; Tagawa, Y.

10.1101/2021.07.21.453297 — neuroscience — Posted on 2021-07-22

1272 DLPacker: Deep Learning for Prediction of Amino Acid Side Chain Conformations in Proteins

Misiura, M.; Shroff, R.; Thyer, R.; Kolomeisky, A.

10.1101/2021.05.23.445347 — biophysics — Posted on 2021-07-22

1273 Modelling the spatiotemporal spread of beneficial alleles using ancient genomes

Muktupavela, R. A.; Petr, M.; Ségurel, L.; Korneliussen, T. S.; Novembre, J.; Racimo, F.

10.1101/2021.07.21.453231 — evolutionary biology — Posted on 2021-07-22

1274 Association between land use, land cover, plant genera, and pollinator abundance in mixed-use landscapes

Diengdoh, V. L.; Brook, B. W.; Hunt, M.; Ondei, S.

10.1101/2021.01.20.427393 — ecology — Posted on 2021-07-22

1275 Defining the prototypical DNA replication fork trap in bacteria

Toft, C.; Moreau, M.; Perutka, J.; Mandapati, S.; Enyeart, P.; Sorenson, A.; Ellington, A.; Schaeffer, P. M.

10.1101/2021.07.20.453168 — molecular biology — Posted on 2021-07-22

1276 Involuntary shifts of spatial attention contribute to behavioral crossmodal distraction - Evidence from oscillatory alpha power and reaction time data

Weise, A.; Hartmann, T.; Parmentier, F.; Weisz, N.; Ruhnau, P.

10.1101/2020.06.29.161992 — neuroscience — Posted on 2021-07-22

1277 Impaired developmental microglial pruning of excitatory synapses on CRH-expressing hypothalamic neurons exacerbates stress responses throughout life

Bolton, J. L.; Short, A. K.; Othy, S.; Kooiker, C. L.; Shao, M.; Gunn, B. G.; Beck, J.; Bai, X.; Law, S. M.; Savage, J. C.; Lambert, J. J.; Belelli, D.; Tremblay, M.-E.; Cahalan, M. D.; Baram, T. Z.

10.1101/2021.07.21.453252 — neuroscience — Posted on 2021-07-22

1278 Dual projecting cells linking thalamic and cortical communication routes between the medial prefrontal cortex and hippocampus

Schlecht, M.; Jayachandran, M.; Rasch, G. E.; Allen, T. A.

10.1101/2021.07.21.453279 — neuroscience — Posted on 2021-07-22

1279 A machine learning model for screening of body fluid cytology smears

Sanyal, P.; Paul, S.; Rana, V.; Kulhari, K.

10.1101/2021.07.20.453010 — pathology — Posted on 2021-07-22

1280 Machine learning models based on molecular descriptors to predict human and environmental toxicological factors in continental freshwater

Servien, R.; Latrille, E.; Patureau, D.; Helias, A.

10.1101/2021.07.20.453034 — biochemistry — Posted on 2021-07-22

1281 Ultrastructure expansion microscopy of Plasmodium gametocytes reveals the molecular architecture of a microtubule organisation centre coordinating mitosis with axoneme assembly

Rashpa, R.; Brochet, M.

10.1101/2021.07.21.453039 — microbiology — Posted on 2021-07-21

1282 Emergence of growth and dormancy from a kinetic model of the Escherichia coli central carbon metabolism

Himeoka, Y.; Mitarai, N.

10.1101/2021.07.21.453212 — systems biology — Posted on 2021-07-21

1283 Systematic analysis of the R2R3-MYB family of transcription factors in Camellia sinensis: evidence for species-specific catechin biosynthesis regulation

Li, J.; Liu, S.; Chen, P.; Cai, J.; Tang, S.; Yang, W.; Cao, F.; Zheng, P.; Sun, B.

10.1101/2021.07.21.453189 — plant biology — Posted on 2021-07-21

1284 Venous activation of MEK/ERK drives development of arteriovenous malformation and blood 2 flow anomalies with loss of Rasa1

Greysson-Wong, J.; Rode, R.; Ryu, J.-R.; Rinker, K. D.; Childs, S. J.

10.1101/2021.07.21.453236 — developmental biology — Posted on 2021-07-21

1285 MyD88-dependent TLR signaling oppositely regulates hematopoietic progenitor and stem cell formation in the embryo

Speck, N. A.; Bennett, L. F.; Mumau, M. D.; Li, Y.

10.1101/2021.07.21.453199 — developmental biology — Posted on 2021-07-21

1286 Cdc14 activates autophagy to regulate spindle pole body dynamics during meiosis

Feng, W.; Arguello-Miranda, O.; Qian, S.; Wang, F.

10.1101/2021.07.21.453268 — cell biology — Posted on 2021-07-21

1287 Efficient inhibition of HIV using CRISPR/Cas13d nuclease system

Nguyen, H.; Wilson, H.; Jayakumar, S.; Kulkarni, V.; Kulkarni, S.

10.1101/2021.07.21.453273 — molecular biology — Posted on 2021-07-21

1288 microRNA-mediated regulation of microRNA machinery controls cell fate decisions

Liu, Q.; Novak, M. K.; Pepin, R. M.; Eich, T.; Hu, W.

10.1101/2021.07.21.453175 — molecular biology — Posted on 2021-07-21

1289 VAL1 as an assembly platform co-ordinating co-transcriptional repression and chromatin regulation at Arabidopsis FLC

Mikulski, P.; Wolff, P.; Lu, T.; Zhu, D.; Dean, C.

10.1101/2021.07.21.453204 — molecular biology — Posted on 2021-07-21

1290 Accurate Segmentation of Bacterial Cells using Synthetic Training Data

Hardo, G.; Noka, M.; Bakshi, S.

10.1101/2021.07.21.453284 — microbiology — Posted on 2021-07-21

1291 Mixed culture metagenomics of the microbes making sour beer

Piraine, R. E. A.; Leite, F. P. L.; Bochman, M. L.

10.1101/2021.07.21.453094 — microbiology — Posted on 2021-07-21

1292 Colistin resistance in Escherichia coli confers protection of the cytoplasmic but not outer membrane from the polymyxin antibiotic

Humphrey, M.; Larrouy-Maumus, G.; Furniss, C.; Mavridou, D.; Sabnis, A.; Edwards, A. M.

10.1101/2021.07.21.453182 — microbiology — Posted on 2021-07-21

1293 Gram-positive bacteria secrete RNA aptamers to activate human STING for IL-1β release.

Duduskar, S. N.; Ghait, M.; Westermann, M.; Guo, H.; Ramoji, A.; Sponholz, C.; Goehrig, B.; Bruns, T.; Neugebauer, U.; Popp, J.; Tuchscherr, L. P. N.; Loeffler, B.; Ueberschaar, N.; Beemelmanns, C.; Singer, M.; Bauer, M.; Deshmukh, S. D.

10.1101/2021.07.21.453173 — immunology — Posted on 2021-07-21

1294 Genome-Wide Identification and Characterization of Fusarium circinatum-Responsive lncRNAs in Pinus radiata

Zamora-Ballesteros, C.; Martin-Garcia, J.; Suarez-Vega, A.; Diez, J.

10.1101/2021.07.21.453138 — plant biology — Posted on 2021-07-21

1295 Analysis of genotype by environment interactions in a maize mapping population

Hudson, A. I.; Odell, S. G.; Dubreuil, P.; Tixier, M.-H.; Praud, S.; Runcie, D. E.; Ross-Ibarra, J.

10.1101/2021.07.21.453280 — plant biology — Posted on 2021-07-21

1296 Reduced protein kinase C delta association with a higher molecular weight complex in mitochondria of Barth Syndrome lymphoblasts

Mejia, E. M.; Zegallai, H. M.; Sparagna, G. C.; Hatch, G. M.

10.1101/2021.07.21.453087 — biochemistry — Posted on 2021-07-21

1297 Short-chain fatty acids activate acetyltransferase p300

Thomas, S.; Denu, J.

10.1101/2021.07.21.453192 — biochemistry — Posted on 2021-07-21

1298 A pair of transporters controls mitochondrial Zn2+ levels to maintain mitochondrial homeostasis

Ma, T.; Zhao, L.; Zhang, J.; Tang, R.; Wang, X.; Liu, N.; Zhang, Q.; Wang, F.; Li, M.; Shan, Q.; Yang, Y.; Yin, Q.; Yang, L.; Gan, Q.; Yang, C.

10.1101/2021.07.21.453180 — cell biology — Posted on 2021-07-21

1299 Two redundant ubiquitin-dependent pathways of BRCA1 localization to DNA damage sites

Sherker, A.; Chaudhary, N.; Adam, S.; Noordermeer, S. M.; Fradet-Turcotte, A.; Durocher, D.

10.1101/2021.07.21.452958 — molecular biology — Posted on 2021-07-21

1300 Discovery of a small molecule that selectively destabilizes Cryptochrome 1 and enhances life span in p53 knockout mice

Gul, S.; Akyel, Y. K.; Gul, Z. M.; Isin, S.; Korkmaz, T.; Selvi, S.; Danis, I.; Ipek, O. S.; Aygenli, F.; Taskin, A. C.; Ozturk, N.; Ozturk, N.; Ozer Unal, D.; Guzel, M.; Turkay, M.; Okyar, A.; Kavakli, I. H.

10.1101/2021.07.21.453206 — molecular biology — Posted on 2021-07-21

1301 Unlike Chloroquine, mefloquine inhibits SARS-CoV-2 infection in physiologically relevant cells and does not induce viral variants.

Sacramento, C. Q.; Fintelman-Rodrigues, N.; Dias, S. S. G.; Temerozo, J. R.; Da Silva, A. d. P. D.; da Silva, C. S.; Ferreira, A. C.; Mattos, M.; Soares, V. C.; Pereira-Dutra, F.; Miranda, M. D.; Barreto-Vieira, D. F.; da Silva, M. A. N.; de Siqueira Santos, S.; Torres, M.; Rajoli, R. K. R.; Paccanaro, A.; Owen, A.; Bou-Habib, D. C.; Bozza, P. T.; Souza, T. M. L.

10.1101/2021.07.21.451321 — microbiology — Posted on 2021-07-21

1302 Characterization of brown-black pigment isolated from soil bacteria, Beijerinckia fluminensis

Joshi, M. H.; Patil, A. A.; Adivarekar, R. V.

10.1101/2021.07.21.453201 — microbiology — Posted on 2021-07-21

1303 A single oral immunization with a replication-competent adenovirus-vectored vaccine protects mice from influenza respiratory infection

Goffin, E.; Hemmi, S.; Machiels, B.; Gillet, L.

10.1101/2021.07.21.453241 — microbiology — Posted on 2021-07-21

1304 Isolation of wild yeasts from Olympic National Park and Moniliella megachiliensis ONP131 physiological characterization for beer fermentation

Piraine, R. E. A.; Nickens, D. G.; Sun, D. J.; Leite, F. P. L.; Bochman, M. L.

10.1101/2021.07.21.453216 — microbiology — Posted on 2021-07-21

1305 Toxoplasma gondii subverts the host ESCRT machinery for parasite uptake of host cytosolic proteins

Rivera-Cuevas, Y.; Mayoral, J.; Di Cristina, M.; Lawrence, A.-L. E.; Olafsson, E. B.; Thornhill, D.; Waldman, B. S.; Ono, A.; Sexton, J.; Lourido, S.; Weiss, L. M.; Carruthers, V. B.

10.1101/2021.07.21.453261 — microbiology — Posted on 2021-07-21

1306 Microbial association networks in cheese: a meta-analysis

Parente, E.; Zotta, T.; Ricciardi, A.

10.1101/2021.07.21.453196 — microbiology — Posted on 2021-07-21

1307 Single Cell Variability of CRISPR-Cas Interference and Adaptation

McKenzie, R. E.; Keizer, E. M.; Vink, J. N. A.; van Lopik, J.; Büke, F.; Kalkman, V.; Fleck, C.; Tans, S. J.; Brouns, S. J. J.

10.1101/2021.07.21.453200 — microbiology — Posted on 2021-07-21

1308 Maturation, developmental site, and pathology dictate murine neutrophil function

10.1101/2021.07.21.453108 — immunology — Posted on 2021-07-21

1309 The RNA m6A binding protein YTHDF2 promotes the B cell to plasma cell transition.

Turner, D.; Saveliev, A.; Salerno, F.; Matheson, L. S.; Screen, M.; Lawson, H.; Wotherspoon, D.; Kranc, K.; Turner, M.

10.1101/2021.07.21.453193 — immunology — Posted on 2021-07-21

1310 E3 ubiquitin ligase SYVN1 is a key positive regulator for GSDMD-mediated pyroptosis

Shi, Y.; Yang, Y.; Xu, W.; Xu, W.; Fu, X.; Lv, Q.; Xia, J.; Shi, F.

10.1101/2021.07.21.453219 — immunology — Posted on 2021-07-21

1311 Combination of Antiviral Drugs to Inhibit SARS-CoV-2 Polymerase and Exonuclease as Potential COVID-19 Therapeutics

Wang, X.; Sacramento, C. Q.; Jockusch, S.; Chaves, O. A.; Tao, C.; Fintelman-Rodrigues, N.; Chien, M.; Temerozo, J. R.; Li, X.; Kumar, S.; Xie, W.; Patel, D. J.; Meyer, C.; Garzia, A.; Tuschl, T.; Bozza, P. T.; Russo, J. J.; Souza, T. M. L.; Ju, J.

10.1101/2021.07.21.453274 — pharmacology and toxicology — Posted on 2021-07-21

1312 Evaluation of sample preservation and storage methods for metaproteomics analysis of intestinal microbiomes

Mordant, A.; Kleiner, M.

10.1101/2021.07.20.453169 — microbiology — Posted on 2021-07-21

1313 Timing of water limitations affects source to sink differences in δ13C composition in apple

Kalcsits, L.; Valverdi, N.; Reid, M.

10.1101/2021.07.20.453133 — plant biology — Posted on 2021-07-21

1314 A novel PD-L1-targeted shark VNAR single domain-based CAR-T strategy for treating breast cancer and liver cancer

Li, D.; English, H.; Hong, J.; Liang, T.; Merlino, G.; Day, C.-P.; Ho, M.

10.1101/2021.07.20.453144 — cancer biology — Posted on 2021-07-21

1315 Displacement statistics of unhindered single molecules show no enhanced diffusion in enzymatic reactions

Choi, A.; Park, H.; Chen, K.; Yan, R.; Li, W.; Xu, K.

10.1101/2021.07.20.452795 — biophysics — Posted on 2021-07-21

1316 Degradation of Red Blood Cell Deformability during Cold Storage in Blood Bags

Islamzada, E.; Matthews, K.; Lamoureux, E.; Duffy, S. P.; Scott, M. D.; Ma, H.

10.1101/2021.07.20.452409 — bioengineering — Posted on 2021-07-21

1317 The impact of rheotaxis and flow on the aggregation of organisms

Painter, K. J.

10.1101/2021.07.20.453166 — animal behavior and cognition — Posted on 2021-07-21

1318 The interplay of additivity, dominance, and epistasis in a diploid yeast cross

Matsui, T.; Mullis, M.; Roy, K.; Hale, J.; Schell, R.; Levy, S. F.; Ehrenreich, I.

10.1101/2021.07.20.453124 — genetics — Posted on 2021-07-21

1319 Priority effects among amphibian microbes lead to varying levels of Bd infection

Barnes, E. M.; Lewis, J.

10.1101/2021.07.20.453099 — ecology — Posted on 2021-07-21

1320 CFTR modulator response measurements in subjects with cystic fibrosis using 2D differentiated nasal epithelia converted into spheroids

Amatngalim, G. D.; Rodenburg, L. W.; Aalbers, B. L.; Raeven, H. H. M.; Aarts, E. M.; Silva, I. A. L.; Nijenhuis, W.; Vrendenbarg, S.; Kruisselbrink, E.; Brunsveld, J.; van Drunen, C. M.; Michel, S.; de Winter-de Groot, K. M.; Heijerman, H. G.; Kapitein, L. C.; Amaral, M. D.; van der Ent, C. K.; Beekman, J. M.

10.1101/2021.07.20.453105 — cell biology — Posted on 2021-07-21

1321 Defining the prototypical DNA replication fork trap in bacteria

Schaeffer, P. M.; Ellington, A.; Perutka, J.; Enyeart, P.; Mandapati, S.; Moreau, M.; Toft, C.; Sorenson, A.; Perutka, J.

10.1101/2021.07.20.453168 — molecular biology — Posted on 2021-07-21

1322 Distinct Colon Mucosa Microbiomes associated with Tubular Adenomas and Serrated Polyps

Avelar-Barragan, J.; DeDecker, L.; Lu, Z.; Coppedge, B.; Karnes, W.; Whiteson, K.

10.1101/2021.07.20.453135 — microbiology — Posted on 2021-07-21

1323 Functional interactomes of the Ebola virus polymerase identified by proximity proteomics in the context of viral replication

Fang, J.; Pietzsch, C.; Tsaprailis, G.; Crynen, G.; Cho, K. F.; Ting, A. Y.; Bukreyev, A.; de la Torre, J. C.; Saphire, E. O.

10.1101/2021.07.20.453153 — microbiology — Posted on 2021-07-21

1324 Escaping the Fate of Sisyphus: Assessing Resistome Hybridization Baits for Antimicrobial Resistance Gene Capture

Beaudry, M. S.; Thomas, J. C.; Baptista, R.; Sullivan, A.; Norfolk, W.; Devault, A.; Enk, J.; Kieran, T.; Rhodes, O.; Perry, A.; Rose, L.; Bayona-Vasquez, N.; Oladeine, A.; Lipp, E. K.; Sanchez, S.; Glenn, T.

10.1101/2021.07.20.452950 — microbiology — Posted on 2021-07-21

1325 The gut microbiome is associated with cocaine behavior and predicts addiction vulnerability in adult male rats

Suess, G. J.; Kasiah, J.; Simpson, S.; Brennan, M.; Conlisk, D.; Maturin, L.; George, O.; Chassaing, B.; Frantz, K. J.

10.1101/2021.07.20.453110 — neuroscience — Posted on 2021-07-21

1326 A neural signature of automatic lexical access in bilinguals

Aristei, S.; Lochy, A.; Rossion, B.; Schiltz, C.

10.1101/2021.07.20.452909 — neuroscience — Posted on 2021-07-21

1327 Adolescent Development of Biological Rhythms: Estradiol Dependence and Effects of Combined Contraceptives

Grant, A. D.; Wilbrecht, L.; Kriegsfeld, L. J.

10.1101/2021.07.20.453145 — physiology — Posted on 2021-07-21

1328 Sex determination gene transformer regulates the male-female difference in Drosophila fat storage via the Adipokinetic hormone pathway

Wat, L. W.; Chowdhury, Z. S.; Millington, J. W.; Biswas, P.; Rideout, E. J.

10.1101/2021.07.20.453098 — physiology — Posted on 2021-07-21

1329 Mechanism of tissue expansion in the early stage of the migration

Kiran, A.; Kumar, N.; Mehandia, V.

10.1101/2021.07.20.453119 — biophysics — Posted on 2021-07-21

1330 Blood Unit Segments Accurately Represent the Biophysical Properties of Red Blood Cells in Blood Bags but Not Hemolysis

Islamzada, E.; Matthews, K.; Lamoureux, E.; Duffy, S. P.; Scott, M. D.; Ma, H.

10.1101/2021.07.20.453156 — bioengineering — Posted on 2021-07-21

1331 Remodeling of ryanodine receptor isoform 1 channel regulates the sweet and umami perception of Rattus norvegicus

Wang, W.; Lu, D.; Xu, Q.; Jin, Y.; Pang, G.; Liu, Y.

10.1101/2021.07.20.453074 — biochemistry — Posted on 2021-07-21

1332 Early life exposure to high fructose diet induces metabolic dysregulation associated with sex-specific cognitive impairment in adolescent rats.

Barrett, C. E.; Jiang, M.; O'Flaherty, B. G.; Dias, B.; Rainnie, D. G.; Young, L.; Menigoz, A.

10.1101/2021.07.20.453114 — animal behavior and cognition — Posted on 2021-07-21

1333 Mutations in coral soma and sperm imply lifelong stem cell differentiation

Lopez-Nandam, E. H.; Albright, R.; Hanson, E. A.; Sheets, E. A.; Palumbi, S. R.

10.1101/2021.07.20.453148 — genetics — Posted on 2021-07-21

1334 How sequence context-dependent mutability drives mutation rate variation in the genome

Oman, M.; Alam, A.; Ness, R.

10.1101/2021.07.20.453104 — evolutionary biology — Posted on 2021-07-21

1335 Grizzly bear toe amputation due to seasonal overlap with furbearer trapping in southeast British Columbia

Lamb, C.; Smit, L.; Vander Vennen, L.; Mowat, G.; Proctor, M.; McLellan, B.

10.1101/2021.07.06.450999 — ecology — Posted on 2021-07-21

1336 Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy

Eapen, V. V.; Swarup, S.; Hoyer, M. J.; Paulo, J. A.; Harper, J. W.

10.1101/2021.07.19.452535 — cell biology — Posted on 2021-07-21

1337 A model of actin-driven endocytosis explains differences of endocytic motility in budding and fission yeast

Nickaeen, M. M.; Berro, J.; Pollard, T. D.; Slepchenko, B. M.

10.1101/2021.07.20.453152 — cell biology — Posted on 2021-07-21

1338 Probing the association between resting state brain network dynamics and psychological resilience

Kraft, D.; Fiebach, C.

10.1101/2021.07.20.452941 — neuroscience — Posted on 2021-07-21

1339 Nonlinear Functional Network Connectivity In Resting fMRI Data

Motlaghian, S.; Belger, A.; Bustillo, J.; Ford, J.; Lim, K.; Mathalon, D.; Mueller, B.; Oleary, D.; Pearlson, G.; Potkin, S.; Preda, A.; Van Erp, T.; Calhoun, V.

10.1101/2021.07.20.452982 — neuroscience — Posted on 2021-07-21

1340 Uncertainty modulates visual maps during non-instrumental information demand

Li, Y.; Daddaoua, N.; Horan, M.; Gottlieb, J.

10.1101/2021.07.20.453107 — neuroscience — Posted on 2021-07-21

1341 Vision is required for the formation of binocular neurons prior to the classical critical period

Tan, L.; Ringach, D. L.; Zipursky, S. L.; Trachtenberg, J. T.

10.1101/2021.06.15.448591 — neuroscience — Posted on 2021-07-21

1342 Emotion increases the similarity between neural representations of pictures, but not their perceived similarity.

Riberto, M.; Paz, R.; Pobric, G.; Talmi, D.

10.1101/2021.06.21.449164 — neuroscience — Posted on 2021-07-21

1343 Abundance of Nef and p-Tau217 in brains of individuals diagnosed with HIV-associated neurocognitive disorders correlate with disease severance

Pushkarsky, T.; Ward, A. I.; Sviridov, D.; Bukrinsky, M. I.

10.1101/2021.07.20.453134 — neuroscience — Posted on 2021-07-21

1344 Variation in scion water relations mediated by two newly released Geneva series rootstocks

Casagrande Biasuz, E.; Kalcsits, L.

10.1101/2021.07.20.453132 — plant biology — Posted on 2021-07-21

1345 A machine learning model for screening of body fluid cytology smears

Sanyal, P.; Rana, V.; Paul, S.; Kulhari, K.

10.1101/2021.07.20.453010 — pathology — Posted on 2021-07-21

1346 Lung Epithelial Regulation of BCL2 Related Protein A1 (BCL2A1) by Coronaviruses (SARS-CoV) and Type I Interferon Signaling

Chilakamarti, R.

10.1101/2021.07.21.453244 — bioinformatics — Posted on 2021-07-21

1347 cLoops2: a full-stack comprehensive analytical tool for chromatin interactions

Cao, Y.; Liu, S.; Ren, G.; Tang, Q.; Zhao, K.

10.1101/2021.07.20.453068 — bioinformatics — Posted on 2021-07-21

1348 CoVizu: Rapid analysis and visualization of the global diversity of SARS-CoV-2 genomes

Ferreira, R.-C.; Wong, E.; Gugan, G.; Wade, K.; Liu, M.; Munoz Baena, L.; Chato, C.; Lu, B.; Olabode, A. S.; Poon, A.

10.1101/2021.07.20.453079 — bioinformatics — Posted on 2021-07-21

1349 Rapamycin microparticles induce autophagy, prevent senescence and are effective in treatment of Osteoarthritis

Dhanabalan, K. M.; Dravid, A. A.; Agarwal, S.; Sharath, R. K.; Padmanabhan, A. K.; Agarwal, R.

10.1101/2021.07.20.453073 — bioengineering — Posted on 2021-07-21

1350 Exercise-induced changes in climbing performance

Riddle, N. C.; Watanabe, L. P.

10.1101/2021.07.20.452939 — genetics — Posted on 2021-07-21

1351 Tempo of degeneration across independently evolved non-recombining regions

Carpentier, F.; Rodriguez De La Vega, R.; Perlin, M. H.; Wallen, M.; Hood, M.; Giraud, T.

10.1101/2021.07.20.453045 — evolutionary biology — Posted on 2021-07-21

1352 An untargeted metabolomic approach to identify antiviral defense mechanisms in memory leukocytes secreting in vitro IgG anti-SARS-Cov-2

Timperio, A. M.; Gevi, F.; Fanelli, G.; Lelli, V.; Zarletti, G.; Tiberi, M.; De Molfetta, V.; Scapigliati, G.

10.1101/2021.07.20.453042 — cell biology — Posted on 2021-07-21

1353 Circulating osteopontin released by injured kidneys causes pulmonary inflammation and edema

Khamissi, F. Z.; Ning, L.; Kefaloyianni, E.; Dun, H.; Arthanarisami, A.; Keller, A.; Atkinson, J. J.; Li, W.; Wong, B. W.; Dietmann, S.; Lavine, K.; Kreisel, D.; Herrlich, A.

10.1101/2021.07.20.452998 — cell biology — Posted on 2021-07-21

1354 Rewiring phospholipid biosynthesis reveals robustness in membrane homeostasis and uncovers lipid regulatory players.

van Schie, S. N. S.; Peter, A. T. J.; Cheung, N. J.; Michel, A. H.; Peter, M.; Kornmann, B.

10.1101/2021.07.20.453065 — cell biology — Posted on 2021-07-21

1355 A chimeric KaiA-like regulator extends the nonstandard KaiB3-KaiC3 clock system in bacteria

Koebler, C.; Schmelling, N. M.; Pawlowski, A.; Spaet, P.; Scheurer, N. M.; Berwanger, L.; Macek, B.; Axmann, I. M.; Wilde, A.

10.1101/2021.07.20.453058 — microbiology — Posted on 2021-07-21

1356 Cornering an Ever-Evolving Coronavirus: TATX-03, a fully human synergistic multi-antibody cocktail targeting the SARS-CoV-2 Spike Protein with in vivo efficacy

Roodink, I.; van Erp, M.; Li, A.; Potter, S.; van Duijnhoven, S. M. J.; Kuipers, A. J.; Kazemier, B.; van Geffen, E.; Hemrika, W.; Berkeveld, B.; Sonnemans, G.; de Vries, B. S.; Boers, B.; Smits, M.; Meurs, S.; de Pooter, M.; Thom, A.; Duplantis, B. N.; Romijn, R. A.; Houser, J. S.; Bath, J.; Abdiche, Y. N.

10.1101/2021.07.20.452858 — immunology — Posted on 2021-07-21

1357 An Orally Available Cathepsin L Inhibitor Protects Lungs Against SARS-CoV-2-Induced Diffuse Alveolar Damage in African Green Monkeys

Frueh, F. W.; Maneval, D. C.; Bohm, R. P.; Dufour, J. P.; Blair, R. V.; Simpson, S.; Powell, K.; Aye, P. P.; Golden, N. A.; ROY, C. J.; Spencer, S.; Russell-Lodrigue, K.; Plante, K. S.; Plante, J. A.; McKerrow, J. H.; Rappaport, J.

10.1101/2021.07.20.453127 — immunology — Posted on 2021-07-21

1358 Human cortical areas are sparsely connected: Combining histology with diffusion MRI to estimate the absolute number of axons

Rosen, B. Q.; Halgren, E.

10.1101/2021.06.07.447453 — neuroscience — Posted on 2021-07-21

1359 Binocular integrated visual field deficits are associated with changes in local network function in primary open-angle glaucoma: a resting-state fMRI study

Demaria, G.; Invernizzi, A.; Ombelet, D.; Carvalho, J.; Renken, R.; Cornelissen, F.

10.1101/2021.07.19.452985 — neuroscience — Posted on 2021-07-21

1360 Modelling spinal locomotor circuits for movements in developing zebrafish

Roussel, Y.; Gaudreau, S. F.; Kacer, E. R.; Sengupta, M.; Bui, T. V.

10.1101/2021.02.10.430671 — neuroscience — Posted on 2021-07-21

1361 Forearm and hand muscles exhibit high coactivation and overlapping of cortical motor representations

Pazin Tardelli, G.; Souza, V. H.; Hiroshi Matsuda, R.; Cavalcanti Garcia, M. A.; Nazarova, M.; Novikov, P.; Baffa, O.

10.1101/2021.07.20.453121 — neuroscience — Posted on 2021-07-21

1362 Multi-elemental isotope and analog tracer application to measure nutrient uptake and distribution in Malus domestica Borkh.

Gomez, R.; Kalcsits, L.

10.1101/2021.07.20.453131 — plant biology — Posted on 2021-07-20

1363 Distinct shifts in site-specific glycosylation pattern of SARS-CoV-2 spike proteins associated with arising mutations in the D614G and Alpha variants

Kuo, C.-W.; Yang, T.-J.; Chien, Y.-C.; Yu, P.-Y.; Hsu, S.-T. D.; Khoo, K.-H.

10.1101/2021.07.21.453140 — biochemistry — Posted on 2021-07-21

1364 Discovery of nanobodies against SARS-CoV-2 and an uncommon neutralizing mechanism

Li, D.; Li, T.; Zhou, B.; Luo, Z.; Lai, Y.; Huang, S.; Zhou, Y.; Gautam, A.; Bourgeau, S.; Wang, S.; Bao, J.; Tan, J.; Lavillette, D.

10.1101/2021.07.20.453054 — biochemistry — Posted on 2021-07-21

1365 GCAT|Panel, a comprehensive structural variant haplotype map of the Iberian population from high-coverage whole-genome sequencing

Valls-Margarit, J.; Galvan-Femenia, I.; Matias, D.; Blay, N.; Puiggros, M.; Carreras, A.; Salvoro, C.; Cortes, B.; Amela, R.; Farre, X.; Lerga-Jaso, J.; Puig, M.; Sanchez-Herrero, J. F.; Moreno, V.; Perucho, M.; Sumoy, L.; Armengol, L.; Delaneau, O.; Caceres, M.; de Cid, R.; Torrents, D.

10.1101/2021.07.20.453041 — genomics — Posted on 2021-07-21

1366 Integrin activation is an essential component of SARS-CoV-2 infection

Simons, P.; Rinaldi, D.; Bondu, V.; Kell, A.; Bradfute, S.; Lidke, D.; Buranda, T.

10.1101/2021.07.20.453118 — cell biology — Posted on 2021-07-21

1367 SARS-CoV-2 Restructures the Host Chromatin Architecture

Wang, R.; Lee, J.-H.; Xiong, F.; Kim, J.; Al Hasani, L.; Yuan, X.; Shivshankar, P.; Krakowiak, J.; Qi, C.; Wang, Y.; Eltzschig, H. K.; Li, W.

10.1101/2021.07.20.453146 — molecular biology — Posted on 2021-07-21

1368 BashTheBug: a crowd of volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96-well broth microdilution plates.

Fowler, P. W.; Wright, C.; Spiers-Bowers, H.; Zhu, T.; Baeten, E. M.; Hoosdally, S. W.; Gibertoni Cruz, A. L.; Roohi, A.; Kouchaki, S.; Walker, T. M.; Peto, T. E.; Miller, G.; Lintott, C.; Clifton, D.; Crook, D. W.; Walker, A. S.; The CRyPTIC Consortium,

10.1101/2021.07.20.453060 — microbiology — Posted on 2021-07-21

1369 PRE-CLINICAL IMMUNE RESPONSE AND SAFETY EVALUATION OF THE PROTEIN SUBUNIT VACCINE NANOCOVAX FOR COVID-19

Tran, T. N. M.; May, B.; Ung, T. T.; Nguyen, M. K.; Nguyen, T. T.; Dinh, V. L.; Tran, T. V.; Khong, H.; Nguyen, T. T.; Hua, H. Q. H.; Nguyen, V. A.; Ha, T. P.; Phan, D. L.; Nguyen, T. A.; Bui, T. N.; Tu, T. M.; Nguyen, T. T.; Le, T. H.; Dong, T. L.; Huynh, T. H.; Truong, C. T.; Nie, L.; Cao, M. N.; Nguyen, D. K.; Trinh, T. H.; Do, M. S.

10.1101/2021.07.20.453162 — immunology — Posted on 2021-07-21

1370 Immunogenic SARS-CoV2 Epitopes Defined by Mass Spectrometry

Pan, K.; Chiu, Y.; Huang, E.; Chen, M.; Wang, J.; Lai, I.; Singh, S.; Shaw, R.; MacCoss, M. J.; Yee, C.

10.1101/2021.07.20.453160 — immunology — Posted on 2021-07-21

1371 Viral receptor profiles of masked palm civet revealed by single-cell transcriptomics

Chen, D.; Ou, Z.; Wang, H.; Zhang, Y.; Zhu, J.; An, F.; Xu, J.; Ding, X.; Ding, P.; Luo, L.; Wu, W.; Qin, Q.; Wei, Y.; Zhao, W.; Lv, Z.; Lan, T.; Li, M.; Zhang, W.; Liu, H.; Hua, Y.

10.1101/2021.07.20.452903 — immunology — Posted on 2021-07-21

1372 Neural Collision Detection: an open source library to study the three-dimensional interactions of neurons and other tree-like structures

Har-Gil, H.; Jacobson, Y.; Proenneke, A.; Staiger, J. F.; Tomer, O.; Halperin, D.; Blinder, P.

10.1101/2021.07.20.452894 — neuroscience — Posted on 2021-07-21

1373 Measuring fingerpad deformation during active object manipulation

Delhaye, B. P.; Schiltz, F.; Barrea, A.; Thonnard, J.-L.; Lefevre, P.

10.1101/2021.07.20.453037 — neuroscience — Posted on 2021-07-21

1374 From the Modern Synthesis to the Molecular Synthesis: updating how we teach and assess evolution by natural selection

Sievers, M.; Reemts, C.; Dickinson, K.; Mukerji, J.; Beltran, I. B.; Theobald, E. J.; Velasco, V.; Freeman, S.

10.1101/2021.07.19.452979 — scientific communication and education — Posted on 2021-07-21

1375 A mechano-osmotic feedback couples cell volume to the rate of cell deformation

Venkova, L.; Vishen, A. S.; Lembo, S.; Srivastava, N.; Duchamp, B.; Ruppel, A.; Vassilopoulos, S.; Deslys, A.; Garcia Arcos, J. M.; Diz-Munoz, A.; Balland, m.; Joanny, J.-F.; Cuvelier, D.; Sens, P.; Piel, M.

10.1101/2021.06.08.447538 — biophysics — Posted on 2021-07-21

1376 Crystal structures of taxane-tubulin complexes: Implications for the mechanism of microtubule stabilization by Taxol

Prota, A. E.; Lucena-Agell, D.; Ma, Y.; Estevez-Gallego, J.; Roca, C.; Josa-Prado, F.; Goossens, K.; Gimenez-Abian, J. F.; Li, S.; Canales, A.; Bargsten, K.; Andreu, J. M.; Altmann, K.-H.; Olieric, N.; Kamimura, S.; Muehlethaler, T.; Oliva, M. A.; Steinmetz, M. O.; Fang, W.-S.; Diaz, J. F.

10.1101/2021.07.20.453061 — biophysics — Posted on 2021-07-21

1377 CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage

Conners, R.; McLaren, M.; Lapinska, U.; Sanders, K.; Stone, M. R. L.; Blaskovich, M. A. T.; Pagliara, S.; Daum, B.; Rakonjac, J.; Gold, V. A. M.

10.1101/2021.07.20.453082 — biophysics — Posted on 2021-07-21

1378 Knockdown of Dnmt1 links Gene body DNA methylation to regulation of gene expression and maternal-zygotic transition in the wasp Nasonia

Arsala, D.; Wu, X.; Yi, S. V.; Lynch, J. A.

10.1101/2021.02.02.429402 — genomics — Posted on 2021-07-21

1379 Clonal evolution in serially passaged Cryptococcus neoformans x deneoformans hybrids reveals a heterogenous landscape of genomic change

Michelotti, L. A.; Sun, S.; Heitman, J.; James, T. Y.

10.1101/2021.03.02.433606 — genetics — Posted on 2021-07-21

1380 The economics of organellar gene loss and endosymbiotic gene transfer

Kelly, S.

10.1101/2020.10.01.322487 — evolutionary biology — Posted on 2021-07-21

1381 Antibiotics drive expansion of rare pathogens in a chronic infection microbiome model

Varga, J. J.; Zhao, C.; Davis, J. D.; Hao, Y.; Farrell, J. M.; Gurney, J. R.; Voit, E.; Brown, S. P.

10.1101/2021.06.21.449018 — microbiology — Posted on 2021-07-21

1382 Extended-Ensemble Docking to Probe Evolution of Ligand Binding Sites in Proteins Undergoing Large-Scale Structural Changes for Their Function

Kapoor, K.; Thangapandian, S.; Tajkhorshid, E.

10.1101/2021.03.28.437371 — biophysics — Posted on 2021-07-21

1383 Cytopath: Simulation based inference of differentiation trajectories from RNA velocity fields

Gupta, R.; Cerletti, D.; Gut, G.; Oxenius, A.; Claassen, M.

10.1101/2020.12.21.423801 — bioinformatics — Posted on 2021-07-21

1384 Differences in the dynamics of the tandem-SH2 modules of the Syk and ZAP-70 tyrosine kinases

Hobbs, H. T.; Shah, N. H.; Badroos, J. M.; Gee, C. L.; Marqusee, S.; Kuriyan, J.

10.1101/2021.07.20.453126 — biochemistry — Posted on 2021-07-21

1385 The first steps toward a global pandemic: Reconstructing the demographic history of parasite host switches in its native range

Techer, M. A.; Roberts, J. M. K.; Cartwright, R. A.; Mikheyev, A. S.

10.1101/2020.07.30.228320 — genomics — Posted on 2021-07-21

1386 The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth

Sandovici, I.; Georgopoulou, A.; Perez-Garcia, V.; Hufnagel, A. S.; Lopez-Tello, J.; Lam, B. Y. H.; Schiefer, S. N.; Gaudreau, C.; Santos, F.; Hoelle, K.; Yeo, G. S. H.; Burling, K.; Reiterer, M.; Fowden, A. L.; Burton, G. J.; Sferruzzi-Perri, A. N.; Branco, C. M.; Constancia, M.

10.1101/520536 — developmental biology — Posted on 2021-07-21

1387 Drosophila beta-Heavy-Spectrin is required in polarized ensheathing glia that forma diffusion-barrier around the neuropil

Pogodalla, N.; Kranenburg, H.; Rey, S.; Rodrigues, S.; Cardona, A.; Klambt, C.

10.1101/2021.07.21.453164 — neuroscience — Posted on 2021-07-21

1388 Dopamine firing plays a double role in coding reward prediction errors and signaling motivation in a working memory task.

Sarno, S.; Beiran, M.; Falco-Roget, J.; Diaz-deLeon, G.; Rossi-Pool, R.; Romo, R.; Parga, N.

10.1101/2020.05.01.071977 — neuroscience — Posted on 2021-07-21

1389 Regulation of stem cell identity by miR-200a during spinal cord regeneration

Walker, S.; Sabin, K.; Gearhart, M.; Yamamoto, K.; Echeverri, K.

10.1101/2021.07.21.453081 — developmental biology — Posted on 2021-07-21

1390 ASXL3 controls cortical neuron fate specification through extrinsic self-renewal pathways

McGrath, B. T.; Wu, P.; Salvi, S.; Girgla, N.; Xu, C.; Zhu, J.; KC, R.; Tsan, Y.-C.; Moccia, A.; Srivastava, A.; Zhou, X.; Bielas, S. L.

10.1101/2021.07.20.452995 — neuroscience — Posted on 2021-07-21

1391 Comparison of Neutralizing Antibody Titers Elicited by mRNA and Adenoviral Vector Vaccine against SARS-CoV-2 Variants

Tada, T.; Zhou, H.; Samanovic, M. I.; Dcosta, B. M.; Cornelius, A.; Mulligan, M. J.; Landau, N. R.

10.1101/2021.07.19.452771 — immunology — Posted on 2021-07-21

1392 Presence of a SARS-COV-2 protein enhances Amyloid Formation of Serum Amyloid A

Jana, A. K.; Greenwood, A. B.; Hansmann, U. H. E.

10.1101/2021.05.18.444723 — biophysics — Posted on 2021-07-21

1393 coronaSPAdes: from biosynthetic gene clusters to RNA viral assemblies

Meleshko, D.; Hajirasouliha, I.; Korobeynikov, A.

10.1101/2020.07.28.224584 — bioinformatics — Posted on 2021-07-21

1394 Highly potent anti-SARS-CoV-2 multivalent DARPin therapeutic candidates

Walser, M.; Rothenberger, S.; Hurdiss, D. L.; Schlegel, A.; Calabro, V.; Fontaine, S.; Villemagne, D.; Paladino, M.; Hospodarsch, T.; Neculcea, A.; Cornelius, A.; Schildknecht, P.; Matzner, M.; Haenggi, M.; Franchini, M.; Kaufmann, Y.; Schaible, D.; Schlegel, I.; Iss, C.; Looser, T.; Mangold, S.; Herzog, C.; Schiegg, D.; Reichen, C.; Radom, F.; Bosshart, A.; Lehmann, A.; Haeuptle, M. A.; Zuercher, A.; Vagt, T.; Sigrist, G.; Straumann, M.; Proba, K.; Veitonmaki, N.; Dawson, K. M.; Zitt, C.; Mayor, J.; Ryter, S.; Lyoo, H.; Wang, C.; Li, W.; Drulyte, I.; Du, W.; Binz, H. K.; de Waal, L.; Stittela

10.1101/2020.08.25.256339 — immunology — Posted on 2021-07-21

1395 Machine learning models based on molecular descriptors to predict human and environmental toxicological factors in continental freshwater

Servien, R.; Latrille, E.; Patureau, D.; Helias, A.

10.1101/2021.07.20.453034 — biochemistry — Posted on 2021-07-21

1396 Adult medial habenula neurons require GDNF receptor GFRalpha1 for synaptic stability and function

Fernandez-Suarez, D.; Krapacher, F.; Pietrajtis, K.; Andersson, A.; Kisiswa, L.; Diana, M.; Ibanez, C.

10.1101/2021.07.07.451421 — neuroscience — Posted on 2021-07-21

1397 Prevalence of Major Limb Loss (MLL) in Post conflict Acholi sub-region of Northern Uganda: Cross sectional study

Atim, P.; Loum, C. S.; Okello, T. R.; Magada, S. M.; Yagos, W. O.; Abelle, P.; Moro, E. B.; Huck, J.; Redmond, A.; Nirmalan, M.

10.1101/2020.05.14.095836 — scientific communication and education — Posted on 2021-07-21

1398 Deep learning-based segmentation and quantification of podocyte foot process morphology

Butt, L.; Unnersjoe-Jess, D.; Hoehne, M.; Sergei, G.; Witasp, A.; Wernerson, A.; Patrakka, J.; Hoyer, P. F.; Blom, H.; Schermer, B.; Bozek, K.; Benzing, T.

10.1101/2021.06.14.448284 — pathology — Posted on 2021-07-21

1399 Insights into Mus musculus subspecies population structure across Eurasia revealed by whole-genome sequence analysis

Fujiwara, K.; Kawai, Y.; Moriwaki, K.; Takada, T.; Shiroishi, T.; Saitou, N.; Suzuki, H.; Osada, N.

10.1101/2021.02.05.429881 — genomics — Posted on 2021-07-21

1400 Structural model of PORCN illuminates disease-associated variants and drug binding sites

Yu, J.; Liao, P.-J.; Xu, W.; Jones, J. R.; Everman, D. B.; Flanagan-Steet, H.; Keller, T. H.; Virshup, D. M.

10.1101/2021.07.19.452875 — molecular biology — Posted on 2021-07-21

1401 The Neural Basis of Delayed Gratification

Gao, Z.; Wang, H.; Lu, C.; Lu, T.; Froudist-Walsh, S.; Chen, M.; Wang, X.-J.; Hu, J.; Sun, W.

10.1101/2021.03.10.434739 — neuroscience — Posted on 2021-07-21

1402 Large-scale cortical connectivity dynamics of intrinsic neural oscillations support adaptive listening behavior

Alavash, M.; Tune, S.; Obleser, J.

10.1101/2021.02.22.432315 — neuroscience — Posted on 2021-07-21

1403 State transitions in the statistically stable place cell population are determined by rate of perceptual change

Tanni, S.; de Cothi, W.; Barry, C.

10.1101/2021.06.16.448638 — neuroscience — Posted on 2021-07-21

1404 Diverse human astrocyte and microglial transcriptional responses to Alzheimer's pathology

Smith, A.; Davey, K.; Tsartsalis, S.; Khozoie, C.; Fancy, N. N.; Tang, S. S.; Liaptsi, E.; Weinert, M.; McGarry, A.; Muirhead, R. C.; Gentleman, S.; Owen, D. R. J.; Matthews, P. M.

10.1101/2021.07.19.452932 — neuroscience — Posted on 2021-07-21

1405 Diverse human astrocyte and microglial transcriptional responses to Alzheimer's pathology

Matthews, P. M.; Davey, K.; Tsartsalis, S.; Khozoie, C.; Fancy, N. N.; Tang, S. S.; Liaptsi, E.; Weinert, M.; McGarry, A.; Muirhead, R. C.; Gentleman, S.; Owen, D. R. J.

10.1101/2021.07.19.452932 — neuroscience — Posted on 2021-07-20

1406 Development of an exosomal gene signature to detect residual disease in dogs with osteosarcoma using a novel xenograft platform and machine learning

Makielski, K.; Donnelly, A. J.; Khammanivong, A.; Scott, M. C.; Ortiz, A. R.; Galvan, D. C.; Tomiyasu, H.; Amaya, C.; Ward, K.; Montoya, A.; Garbe, J. R.; Mills, L. J.; Cutter, G. R.; Fenger, J. M.; Kisseberth, W. C.; O'Brien, T. D.; Weigel, B. J.; Spector, L. G.; Bryan, B. A.; Subramanian, S.; Modiano, J. F.

10.1101/2021.02.11.429432 — cancer biology — Posted on 2021-07-20

1407 Precise, Fast and Comprehensive Analysis of Intact Glycopeptides and Modified Saccharide Units with pGlyco3

Zeng, W.-F.; Cao, W.-Q.; Liu, M.-Q.; He, S.-M.; Yang, P.-Y.

10.1101/2021.02.06.430063 — bioinformatics — Posted on 2021-07-20

1408 Metabolic turnover and dynamics of modified ribonucleosides by 13C labeling

Gameiro, P. A.; Encheva, V.; Silva dos Santos, M.; MacRae, J. I.; Ule, J.

10.1101/2021.07.20.453046 — biochemistry — Posted on 2021-07-20

1409 Differences in the dynamics of the tandem-SH2 modules of the Syk and ZAP-70 tyrosine kinases

Hobbs, H. T.; Shah, N. H.; Badroos, J. M.; Gee, C. L.; Marqusee, S.; Kuriyan, J.

10.1101/2021.07.20.453126 — biochemistry — Posted on 2021-07-20

1410 Solid state NMR reveals a parallel in register architecture for an infectious recombinant prion

Martin-Pastor, M.; Codeseira, Y. B.; Spagnolli, G.; Erana, H.; Fernandez, L. C.; Martin, D.; Bravo, S.; Lopez-Lorenzo, N.; Iglesias, A.; Lopez-Moreno, R.; Sabate, R.; Veiga, S.; Rezaei, H.; Biasini, E.; Sanchez-Pedregal, V. M.; Castilla, J.; Requena, J. R.

10.1101/2021.07.20.453078 — biochemistry — Posted on 2021-07-20

1411 Hierarchical clustering optimizes the tradeoff between compositionality and expressivity of task structures in reinforcement learning

Liu, R. G.; Frank, M. J.

10.1101/2021.07.20.453122 — animal behavior and cognition — Posted on 2021-07-21

1412 Transcription factor regulation of eQTL activity across individuals and tissues

Flynn, E.; Tsu, A. L.; Kasela, S.; Kim-Hellmuth, S.; Aguet, F.; Ardlie, K. G.; Bussemaker, H. J.; Mohammadi, P.; Lappalainen, T.

10.1101/2021.07.20.453075 — genomics — Posted on 2021-07-20

1413 Comprehensive analyses of RNA-seq and genome-wide data point to enrichment of neuronal cell type subsets in neuropsychiatric disorders

Olislagers, M.; Rademaker, K.; Adan, R.; Lin, B.; Luykx, J.

10.1101/2021.05.06.442982 — genomics — Posted on 2021-07-20

1414 Metagenome-genome-wide association studies reveal human genetic impact on the oral microbiome

Liu, X.; Tong, X.; Zhu, J.; Tian, L.; Jie, Z.; Zou, Y.; Lin, X.; Liang, H.; Li, W.; Ju, Y.; Qin, Y.; Zou, L.; Lu, H.; Xu, X.; Yang, H.; Wang, J.; Zong, Y.; Liu, W.; Hou, Y.; Zhu, S.; Jin, X.; Jia, H.; Zhang, T.

10.1101/2021.05.06.443017 — genetics — Posted on 2021-07-20

1415 Pairs of compensatory frameshifting mutations contribute to evolution of protein-coding sequences in vertebrates and insects

Biba, D.; Klink, G. V.; Bazykin, G. A.

10.1101/2020.12.25.424394 — evolutionary biology — Posted on 2021-07-20

1416 A common gene drive language eases regulatory process and eco-evolutionary extensions

Verma, P.; Reeves, R. G.; Gokhale, C. S.

10.1101/2020.02.28.970103 — evolutionary biology — Posted on 2021-07-20

1417 A comparative network approach to assess the social-ecological underpinnings of zoonotic outbreaks at human-wildlife interfaces

Balasubramaniam, K. N.; Aiempichitkijkarn, N.; Kaburu, S. S. K.; Marty, P. R.; Beisner, B. A.; Bliss-Moreau, E.; Arlet, M. E.; Atwill, E. R.; McCowan, B.

10.1101/2021.07.19.452944 — ecology — Posted on 2021-07-20

1418 Mechanisms of translation inhibition and suppression of Stress Granule formation by cisplatin

Pietras, P.; Aulas, A.; Fay, M. M.; Lesniczak, M.; Lyons, S. M.; Szaflarski, W.; Ivanov, P.

10.1101/2021.07.20.452628 — cell biology — Posted on 2021-07-20

1419 ENKD1 is a centrosomal and ciliary microtubule-associated protein important for primary cilium assembly and Hedgehog signaling

Tiryaki, F.; Deretic, J.; Firat-Karalar, E. N.

10.1101/2021.07.20.453048 — cell biology — Posted on 2021-07-20

1420 Tensin3 interaction with talin drives formationof fibronectin-associated fibrillar adhesions

Atherton, P.; Konstantinou, R.; Neo, S. P.; Wang, E.; Balloi, E.; Ptushkina, M.; Bennett, H.; Clark, K.; Gunaratne, J.; Critchley, D.; Barsukov, I.; Manser, E.; Ballestrem, C.

10.1101/2021.07.16.452612 — cell biology — Posted on 2021-07-20

1421 ChAdOx1 NiV vaccination protects against lethal Nipah Bangladesh virus infection in African green monkeys

van Doremalen, N.; Avanzato, V.; Feldmann, F.; Schulz, J.; Haddock, E.; Okumura, A.; Lovaglio, J.; Hanley, P.; Cordova, K.; Saturday, G.; Lambe, T.; Gilbert, S. C.; Munster, V.

10.1101/2021.07.20.452991 — microbiology — Posted on 2021-07-20

1422 ENGINEERING, DECODING AND SYSTEMS-LEVEL CHARACTERIZATION OF CHIMPANZEE CYTOMEGALOVIRUS

Phan, Q. V.; Bogdanow, B.; Wyler, E.; Landthaler, M.; Liu, F.; Hagemeier, C.; Wiebusch, L.

10.1101/2021.07.20.453063 — microbiology — Posted on 2021-07-20

1423 Discovery of genes that modulate flavivirus replication in an interferon-dependent manner

Lesage, S.; Chazal, M.; Beauclair, G.; Batalie, D.; Couderc, E.; Lescure, A.; Del Nery, E.; Tangy, F.; Martin, A.; Manel, N.; jouvenet, n.

10.1101/2021.07.20.453077 — microbiology — Posted on 2021-07-20

1424 Immunodominant surface epitopes power immune evasion in the African trypanosome

Gkeka, A.; Aresta-Branco, F.; Triller, G.; Vlachou, E. P.; Lilic, M.; Olinares, P. D. B.; Perez, K.; Chait, B.; Blatnik, R.; Ruppert, T.; Stebbins, C. E.; Papavasiliou, F. N.

10.1101/2021.07.20.453071 — immunology — Posted on 2021-07-20

1425 Engineering well-expressed, V2-immunofocusing HIV-1 envelope glycoprotein membrane trimers for use in heterologous prime-boost vaccine regimens

Binley, J. M.; Crooks, E.; Almanza, F.; D'Addabbo, A.; Duggan, E.; Zhang, J.; Wagh, K.; Mou, H.; Allen, J.; Thomas, A.; Osawa, K.; Korber, B.; Tsybovsky, Y.; Cale, E.; Nolan, J.; Crispin, M.; Verkoczy, L.

10.1101/2021.07.20.453076 — immunology — Posted on 2021-07-20

1426 Engineered Bacteriophage T4 Nanoparticle as a Potential Targeted Activator of HIV-1 Latency in CD4+ Human T cells

Batra, H.; Zhu, J.; Jain, S.; Ananthaswamy, N.; Mahalingam, M.; Tao, P.; Lange, C.; Zhong, C.; Kearney, M. F.; Hu, H.; Maldarelli, F.; Rao, V. B.

10.1101/2021.07.20.453091 — immunology — Posted on 2021-07-20

1427 Deficient thalamo-cortical networks dynamics and sleep homeostatic processes in a redox dysregulation model relevant to schizophrenia.

Czekus, C.; Steullet, P.; Rusterholz, T.; Bozic, I.; Do Cuenod, K.; Bandarabadi, M.; Gutierrez Herrera, C.

10.1101/2021.07.20.453026 — neuroscience — Posted on 2021-07-20

1428 Cuticular Wax Composition is Essential for Plant Recovery Following Drought with Little Effect under Optimal Conditions

Negin, B.; Hen-Avivi, S.; Almekias-Siegl, E.; Shachar, L.; Aharoni, A.

10.1101/2021.06.08.447487 — plant biology — Posted on 2021-07-20

1429 Redox regulation by TXNRD3 during epididymal maturation underlies capacitation-associated mitochondrial activation and sperm motility in mice

Wang, H.; Dou, Q.; Jung, K. J.; Choi, J.; Gladyshev, V. N.; Chung, J.-J.

10.1101/2021.07.19.452987 — physiology — Posted on 2021-07-20

1430 Deep learning-based segmentation and quantification of podocyte foot process morphology

Butt, L.; Unnersjoe-Jess, D.; Hoehne, M.; Sergei, G.; Witasp, A.; Wernerson, A.; Patrakka, J.; Hoyer, P. F.; Blom, H.; Schermer, B.; Bozek, K.; Benzing, T.

10.1101/2021.06.14.448284 — pathology — Posted on 2021-07-20

1431 The Interplay of Electrostatics and Chemical Positioning in the Evolution of Antibiotic Resistance in TEM β-Lactamases

Schneider, S. H.; Kozuch, J.; Boxer, S. G.

10.1101/2021.05.27.446023 — biophysics — Posted on 2021-07-20

1432 Environmentally sensitive hotspots in the methylome of the early human embryo

Silver, M. J.; Saffari, A.; Kessler, N. J.; Chandak, G. R.; Fall, C. H.; Issarapu, P.; Dedaniya, A.; Betts, M.; Moore, S. E.; Routledge, M. N.; Herceg, Z.; Cuenin, C.; Derakhshan, M.; James, P. T.; Monk, D.; Prentice, A. M.

10.1101/777508 — genomics — Posted on 2021-07-20

1433 Benchmarking ultra-high molecular weight DNA preservation methods for long-read and long-range sequencing

Dahn, H. A.; Mountcastle, J.; Balacco, J.; Winkler, S.; Bista, I.; Schmitt, A. D.; Vinnere Pettersson, O.; Formenti, G.; Oliver, K.; Smith, M.; Tan, W.; Kraus, A.; Mac, S.; Komoroske, L. M.; Lama, T.; Crawford, A. J.; Murphy, R. W.; Brown, S.; Scott, A. F.; Morin, P. A.; Jarvis, E. D.; Fedrigo, O.

10.1101/2021.07.13.451380 — genomics — Posted on 2021-07-20

1434 Spontaneous emergence of multicellular heritability

Zamani-Dahaj, S. A.; Burnetti, A.; Day, T. C.; Yunker, P. J.; Ratcliff, W. C.; Herron, M. D.

10.1101/2021.07.19.452990 — evolutionary biology — Posted on 2021-07-20

1435 The genetic basis of cooperation and conflict in natural populations of a model symbiont

Batstone, R. T.; Burghardt, L. T.; Heath, K. D.

10.1101/2021.07.19.452989 — evolutionary biology — Posted on 2021-07-20

1436 SUV39 SET domains mediate crosstalk of heterochromatic histone marks

Stirpe, A.; Guidotti, N.; Northall, S.; Kilic, S.; Hainard, A.; Vadas, O.; Fierz, B.; Schalch, T.

10.1101/2020.06.30.177071 — molecular biology — Posted on 2021-07-20

1437 The angiotensin antagonist Losartan shifts social reward motivation and punishment feedback sensitivity via modulating midbrain-striato-frontal circuits

Zhou, X.; Xu, T.; Zeng, Y.; Zhang, R.; Qi, Z.; Zhao, W.; Kendrick, K. M.; Becker, B.

10.1101/2021.07.19.452920 — neuroscience — Posted on 2021-07-20

1438 Resonating neurons stabilize heterogeneous grid-cell networks

Mittal, D.; Narayanan, R.

10.1101/2020.12.10.419200 — neuroscience — Posted on 2021-07-20

1439 A laboratory module that explores RNA interference and codon optimization through fluorescence microscopy using Caenorhabditis elegans

Palmisano, N. J.; Azmi, M. A.; Medwig-Kinney, T. N.; Moore, F. E.; Rahman, R.; Zhang, W.; Adikes, R. C.; Matus, D. Q.

10.1101/2020.10.17.344069 — scientific communication and education — Posted on 2021-07-20

1440 Field Potential Image Classification of Pacemaker Micro-coordination in the Intestine of the Mouse

Iwata, N.; Takai, C.; Mochizuki, N.; Yamauchi, M.; Kasahara, Y.; Nakayama, S.

10.1101/2021.05.29.446256 — physiology — Posted on 2021-07-20

1441 Ultrafast end-to-end protein structure prediction enables high-throughput exploration of uncharacterised proteins

Kandathil, S. M.; Greener, J. G.; Lau, A. M.; Jones, D. T.

10.1101/2020.11.27.401232 — bioinformatics — Posted on 2021-07-20

1442 PepNN: a deep attention model for the identification of peptide binding sites

Abdin, O.; Nim, S.; Wen, H.; Kim, P. M.

10.1101/2021.01.10.426132 — bioinformatics — Posted on 2021-07-20

1443 A Bayesian model selection approach to mediation analysis

Crouse, W. L.; Keele, G. R.; Gastonguay, M. S.; Churchill, G. A.; Valdar, W.

10.1101/2021.07.19.452969 — genetics — Posted on 2021-07-20

1444 The relative impact of evolving pleiotropy and mutational correlation on trait divergence

Chebib, J.; Guillaume, F.

10.1101/702407 — evolutionary biology — Posted on 2021-07-20

1445 GLOBAL LAND-USE AND LAND-COVER DATA: HISTORICAL, CURRENT AND FUTURE SCENARIOS

Vale, M. M.; Lima Ribeiro, M. S.; Rocha, T. C.

10.1101/2021.05.06.442941 — ecology — Posted on 2021-07-20

1446 Decoding regulatory specificity of human ribosomal proteins

Luan, Y.; Tang, N.; Yang, J.; Chen, C.; Liu, S.; Cheng, C.; Wang, Y.; Guo, Y.; Wang, H.; Xiang, M.; Ju, R.; Xie, Z.

10.1101/2021.03.27.437302 — cell biology — Posted on 2021-07-20

1447 Cross-tissue immune cell analysis reveals tissue-specific adaptations and clonal architecture across the human body

Dominguez Conde, C.; Gomes, T.; Jarvis, L. B.; Xu, C.; Howlett, S.; Rainbow, D.; Suchanek, O.; King, H.; Mamanova, L.; Polanski, K.; Huang, N.; Fasouli, E.; Mahbubani, K.; Prete, M.; Tuck, E.; Richoz, N.; Tuong, K.; Campos, L.; Mousa, H.; Needham, E.; Pritchard, S.; Li, T.; Elmentaite, R.; Park, J.; Menon, D.; Bayraktar, O.; James, L.; Meyer, K.; Clatworthy, M.; Saeb-Parsy, K.; Jones, J. L.; Teichmann, S. A.

10.1101/2021.04.28.441762 — immunology — Posted on 2021-07-20

1448 Reduction in CD11c+ microglia correlates with clinical progression in chronic experimental autoimmune demyelination

Mayrhofer, F.; Dariychuk, Z.; Zhen, A.; Daugherty, D. J.; Bannerman, P.; Hanson, A. M.; Pleasure, D. E.; Soulika, A.; Deng, W.; Chechneva, O.

10.1101/396036 — neuroscience — Posted on 2021-07-20

1449 Hierarchical Computational Anatomy: Unifying the Molecular to Tissue Continuum via Measure Representations of the Brain

Miller, M. I.; Tward, D. J.; Trouve, A.

10.1101/2021.04.19.440540 — neuroscience — Posted on 2021-07-20

1450 Deep learning and cross-species analysis identify the influences of sex and cannabinoidsignaling on cerebellar vermis morphology

Black, K. C.; McPherson, B. C.; Hainline, J.; Baygani, S.; Webb, B.; Mier, T. J.; Essex, A.; Mackie, K.; Pestilli, F.; Kalinovsky, A.

10.1101/2021.07.03.450642 — neuroscience — Posted on 2021-07-20

1451 Cognitive functions and underlying parameters of human brain physiology are associated with chronotype

Salehinejad, M. A.; Wischnewski, M.; Ghanavati, E.; Mosayebi-Samani, M.; Kuo, M.-F.; Nitsche, M. A.

10.1101/2021.06.08.447543 — neuroscience — Posted on 2021-07-20

1452 Loss of Nuclear DNA Ligase III Reverts PARP Inhibitor Resistance in BRCA1/53BP1 Double-deficient Cells by Exposing ssDNA Gaps

Paes Dias, M.; Tripathi, V.; Heijden, I. v. d.; Cong, K.; Manolika, E.-M.; Bhin, J.; Gogola, E.; Galanos, P.; Annunziato, S.; Lieftink, C.; Andujar-Sanchez, M.; Chakrabarty, S.; Smith, G. C. M.; Ven, M. v. d.; Beijersbergen, R. L.; Bartkova, J.; Rottenberg, S.; Cantor, S.; Bartek, J.; Chaudhuri, A. R.; Jonkers, J.

10.1101/2021.03.24.436323 — cancer biology — Posted on 2021-07-20

1453 Lipid-induced polymorphic amyloid fibrils formation by α-synuclein.

Singh, B. P.; Morris, R. J.; Horrocks, M. H.; Kunath, T.; MacPhee, C. E.

10.1101/2021.07.20.453062 — biophysics — Posted on 2021-07-20

1454 Closed-loop sacral neuromodulation for bladder function using dorsal root ganglia sensory feedback in an acute feline model

Ouyang, Z.; Barrera, N.; Sperry, Z. J.; Bottorff, E. C.; Bittner, K. C.; Zirpel, L.; Bruns, T. M.

10.1101/2020.05.02.074484 — bioengineering — Posted on 2021-07-20

1455 Growth and immunolocalisation of the brown alga Ectocarpus in a microfluidic environment

Charrier, B.; Boscq, S.; Nelson, B. J.; Laubli, N. F.

10.1101/2021.07.20.453111 — cell biology — Posted on 2021-07-20

1456 Plant-associated Pseudomonas aeruginosa harbor multiple virulence traits essential for mammalian infection

Ambreetha, S.; Marimuthu, P.; Mathee, K.; Balachandar, D.

10.1101/2021.07.20.453120 — microbiology — Posted on 2021-07-20

1457 Genotype of Human Papilloma virus in Male Genital Warts In Korean Men and Review of Literature

Moon, J. J.; Moon, W. C.; Yoon, J.; Jo, J.

10.1101/2021.07.19.453017 — microbiology — Posted on 2021-07-20

1458 The efficacy of antimicrobial agents is decreased in a polymicrobial environment

O'Brien, T. J.; Figueroa, W.; Welch, M.

10.1101/2021.07.20.453069 — microbiology — Posted on 2021-07-20

1459 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription

Arragain, B.; Trouilleton, Q. D.; Baudin, F.; Cusack, S.; Schoehn, G.; MALET, H.

10.1101/2021.07.20.453038 — microbiology — Posted on 2021-07-20

1460 Single-cell genomics reveals region-specific developmental trajectories underlying neuronal diversity in the prenatal human hypothalamus

Herb, B.; Glover, H. J.; Bhaduri, A.; Casella, A. M.; Bale, T. L.; Kriegstein, A.; Doege, C.; Ament, S. A.

10.1101/2021.07.20.453090 — neuroscience — Posted on 2021-07-20

1461 Myotubularin-related phosphatase 5 is a critical determinant of autophagy in neurons

Chua, J. P.; Bedi, K.; Paulsen, M. T.; Ljungman, M.; Tank, E. M. H.; Kim, E. S.; Colon-Mercado, J. M.; Ward, M. E.; Weisman, L. S.; Barmada, S. J.

10.1101/2021.07.20.453106 — neuroscience — Posted on 2021-07-20

1462 Co-transcriptional RNA strand displacement circuits

Schaffter, S. W.; Strychalski, E.

10.1101/2021.07.20.450530 — synthetic biology — Posted on 2021-07-20

1463 Regulation of a bacterial histidine kinase by a phase separating scaffolding protein

Zhang, C.; Zhao, W.; Duvall, S. W.; Kowallis, K.; Childers, W. S.

10.1101/2021.07.20.452843 — synthetic biology — Posted on 2021-07-20

1464 The Tabula Sapiens: a single cell transcriptomic atlas of multiple organs from individual human donors

The Tabula Sapiens Consortium, ; Quake, S. R.

10.1101/2021.07.19.452956 — cell biology — Posted on 2021-07-20

1465 Previously unrecognized non-reproducible antibody-antigen interactions and their implications for diagnosis of viral infections including COVID-19

Pan, J.; Yang, L.; Deng, Y.; Sun, B.; Zhang, L.; Wu, W.; Li, J.; Cheng, H.; Li, Y.; Xu, W.; Yang, J.; Sun, Y.; Fei, H.; Xue, Q.; Zhou, Y.; Wang, H.; Zheng, P.; Chen, H.; Zhu, F. C.; Peng, D.; Gu, D.; Han, J.; Qiu, J.; Ma, H.

10.1101/2021.07.20.453011 — immunology — Posted on 2021-07-20

1466 HLA-dependent variation in SARS-CoV-2 CD8+ T cell cross-reactivity with human coronaviruses

Buckley, P.; Lee, C. H.-j.; Pinho, M. P.; Babu, R. O.; Woo, J.; Antanaviciute, A.; Simmons, A.; Ogg, G.; Koohy, H.

10.1101/2021.07.17.452778 — immunology — Posted on 2021-07-20

1467 The SARS-CoV-2 reproduction number R0 in cats

Gonzales, J. L.; De Jong, M. C. M.; Gerhards, N. M.; Van der Poel, W. H. M.

10.1101/2021.07.20.453027 — microbiology — Posted on 2021-07-20

1468 CRISPR screens for host factors critical for infection by SARS-CoV-2 variants of concern identify GATA6 as a central modulator of ACE2.

Israeli, M.; Finkel, Y.; Israeli, O.; Beth-Din, A.; Cohen-Gihon, I.; Yahalom-Rone, Y.; Paran, N.; Israely, T.; Chitlaru, T.; Elia, U.; Cohen, O.; Nemet, I.; Kliker, L.; Mandelboim, M.; Stern-Ginossar, N.; Bercovich-Kinori, A.

10.1101/2021.07.19.452809 — microbiology — Posted on 2021-07-20

1469 The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147-receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease

Avolio, E.; Carrabba, M.; Milligan, R.; Kavanagh Williamson, M.; Beltrami, A. P.; Gupta, K.; Elvers, K. T.; Gamez, M.; Foster, R.; Gillespie, K.; Hamilton, F.; Arnold, D.; Berger, I.; Caputo, M.; Davidson, A. D.; Hill, D.; Madeddu, P.

10.1101/2020.12.21.423721 — cell biology — Posted on 2021-07-20

1470 Phylogenomic analyses of echinoid diversification prompt a re-evaluation of their fossil record

Mongiardino Koch, N.; Thompson, J. R.; Hatch, A. S.; McCowin, M. F.; Armstrong, F.; Coppard, S. E.; Aguilera, F.; Bronstein, O.; Kroh, A.; Mooi, R.; Rouse, G.

10.1101/2021.07.19.453013 — evolutionary biology — Posted on 2021-07-20

1471 Multi-omics analysis identifies essential regulators of mitochondrial stress response in two wild-type C. elegans strains

Gao, A. W.; El Alam, G.; Lalou, A.; Li, T. Y.; Molenaars, M.; Zhu, Y.; Overmyer, K. A.; Shishkova, E.; Hof, K.; Bou Sleiman, M. S.; Houtkooper, R. H.; Coon, J.; Auwerx, J.

10.1101/2021.07.20.453059 — systems biology — Posted on 2021-07-20

1472 Tissue-engineered collagenous fibrous cap models to systematically elucidate atherosclerotic plaque rupture.

Wissing, T. B.; Van der Heiden, K.; Serra, S. M.; Smits, A. I. P. M.; Bouten, C. V. C.; Gijsen, F.

10.1101/2021.07.20.451997 — bioengineering — Posted on 2021-07-20

1473 Patterns of mesozooplankton community composition and vertical fluxes in the global ocean

Soviadan, Y. D.; benedetti, f.; brandao, m.; ayata, s. d.; Irisson, j. o.; jamet, j. l.; kiko, r.; Lombard, F.; Gnandi, K.; stemmann, l.

10.1101/2021.07.20.452978 — ecology — Posted on 2021-07-20

1474 MCPH1 inhibits condensin II during interphase by regulating its SMC2-kleisin interface.

Houlard, M.; Cutts, E.; S. Shamim, M.; Godwin, J.; Weisz, D.; Presser Aiden, A.; Lieberman Aiden, E.; Schermelleh, L.; Vannini, A.; Nasmyth, K.

10.1101/2021.07.20.453033 — cell biology — Posted on 2021-07-20

1475 Integration of the cyanophage-encoded phosphate binding protein into the cyanobacterial phosphate uptake system

Zhao, F.; Lin, X.; Cai, K.; Jiang, Y.; Ni, T.; Chen, Y.; Feng, J.; Dang, S.; Zhou, C.-Z.; Zeng, Q.

10.1101/2021.07.20.453049 — microbiology — Posted on 2021-07-20

1476 Protein kinase Cδ is essential for the IgG response against T cell-independent type 2 antigens and commensal bacteria

Kitamura, D.; Fukao, S.; Haniuda, K.; Tamaki, H.

10.1101/2021.07.20.453051 — immunology — Posted on 2021-07-20

1477 Dynamics of synthetic yeast chromosome evolution shaped by hierarchical chromatin organization

Zhou, S.; Wu, Y.; Zhang, Z.; Jiang, L.; Liu, L.; Zhang, Y.; Tang, J.; Yuan, Y.-J.

10.1101/2021.07.19.453002 — synthetic biology — Posted on 2021-07-20

1478 Spectral estimation of in-vivo wheat chlorophyll a/b ratio under contrasting water availabilities

Mulero, G.; Bacher, H.; Kleiner, U.; Peleg, Z.; Herrmann, I.

10.1101/2021.07.19.453016 — physiology — Posted on 2021-07-20

1479 Facilitation of TRKB activation by the angiotensin II receptor type-2 (AT2R) agonist C21

Laukkanen, L.; Dinz, C. R. A. F.; Foulquier, S.; Prickaerts, J.; Castren, E.; Casarotto, P. C.

10.1101/2021.07.20.453028 — pharmacology and toxicology — Posted on 2021-07-20

1480 Somatic point mutations are enriched in long non-coding RNAs with possible regulatory function in breast cancer

Rezaie, N.; Bayati, M.; Tahaei, M. S.; Hamidi, M.; Khorasani, S.; Lovell, N. H.; Breen, J.; Rabiee, H. R.; Alinejad-Rokny, H.

10.1101/2021.07.19.453012 — cancer biology — Posted on 2021-07-20

1481 Imaging biological samples by integrated differential phase contrast (iDPC) STEM technique

Li, X.; Lazic, I.; Huang, X.; Wang, L.; Deng, Y.; Niu, T.; Wu, D.; Wirix, M.; Yu, L.; Sun, F.

10.1101/2021.07.20.453030 — biophysics — Posted on 2021-07-20

1482 The mitotic spindle protein CKAP2 potently increases formation and stability of microtubules

Bechstedt, S.; McAlear, T. S.

10.1101/2021.07.20.453056 — biophysics — Posted on 2021-07-20

1483 PSINDB: A comprehensive database of postsynaptic protein-protein interactions

Kalman, Z. E.; Dudola, D.; Meszaros, B.; Gaspari, Z.; Dobson, L.

10.1101/2021.07.19.453019 — bioinformatics — Posted on 2021-07-20

1484 FISH-quant v2: a scalable and modular analysis tool for smFISH image analysis

Imbert, A.; Ouyang, W.; Safieddine, A.; Coleno, E.; Zimmer, C.; Bertrand, E.; Walter, T.; Mueller, F.

10.1101/2021.07.20.453024 — bioinformatics — Posted on 2021-07-20

1485 Task-Assisted GAN for Resolution Enhancement and Modality Translation in Fluorescence Microscopy

Bouchard, C.; Wiesner, T.; Deschenes, A.; Lavoie-Cardinal, F.; Gagne, C.

10.1101/2021.07.19.452964 — bioinformatics — Posted on 2021-07-20

1486 Machine learning models based on molecular descriptors to predict human and environmental toxicological factors in continental freshwater

Servien, R.; Latrille, E.; Patureau, D.; Helias, A.

10.1101/2021.07.20.453034 — biochemistry — Posted on 2021-07-20

1487 Strategies of tolerance reflected in two North American maple genomes

McEvoy, S. L.; Sezen, U. U.; Trouern-Trend, A.; McMahon, S. M.; Schaberg, P. G.; Yang, J.; Wegrzyn, J. L.; Swenson, N. G.

10.1101/2021.07.19.452996 — genomics — Posted on 2021-07-20

1488 Phylo-taxonogenomics of 182 strains of genus Leuconostoc elucidates its robust taxonomy and biotechnological importance

Kumar, S.; Bansal, K.; Sethi, S. K.; Bindhani, B. K.

10.1101/2021.07.20.453025 — genomics — Posted on 2021-07-20

1489 Detecting change in interconnected ecosystem assets to inform indicators of condition in environmental economic accounts

Brown, C. J.; Saint Ange, C.; Connolly, R.; Hasan, S.; Jackson, S.; McMahon, J.; Smart, J.

10.1101/2021.07.19.453015 — ecology — Posted on 2021-07-20

1490 Mcc1229, an Stx2a-amplifying microcin, is produced in vivo and requires CirA for activity

Nawrocki, E. M.; Hutchins, L. E.; Eaton, K.; Dudley, E. G.

10.1101/2021.07.19.453020 — microbiology — Posted on 2021-07-20

1491 Don't think, feel: basal ganglia-cortical connectivity underlies self-regulation of brain oscillations in humans

Kasahara, K.; DaSalla, C. S.; Honda, M.; Hanakawa, T.

10.1101/2021.07.19.453008 — neuroscience — Posted on 2021-07-20

1492 Fast grip force adaptation to friction relies on localized fingerpad strains

Schiltz, F.; Delhaye, B. P.; Crevecoeur, F.; Thonnard, J.-L.; Lefevre, P.

10.1101/2021.07.20.452911 — neuroscience — Posted on 2021-07-20

1493 Dendrite regeneration in C. elegans is controlled by the RAC GTPase CED-10 and the RhoGEF TIAM-1

Brar, H. K.; Dey, S.; Bhardwaj, S.; Pande, D.; Singh, P.; Dey, S.; Ghosh-Roy, A.

10.1101/2021.07.20.453023 — neuroscience — Posted on 2021-07-20

1494 Sex differences in tissue gene regulation -- contributions of three classes of sex-biasing factors

Blencowe, M.; Itoh, Y.; Chen, X.; Zhao, Y.; Han, Y.; Shou, B.; McClusky, R.; Reue, K.; Arnold, A. P.; Yang, X.

10.1101/2021.07.18.451543 — systems biology — Posted on 2021-07-20

1495 The diversity of quinoa morphological traits and seed metabolic composition

Tabatabaei, I.; Alseekh, S.; Shahid, M.; Leniak, E.; Wagner, M.; Mahmoudi, H.; Thushar, S.; Fernie, A. R.; Murrphy, K. M.; Schmöckel, S. M.; Tester, M.; Mueller-Roeber, B.; Skirycz, A.; Balazadeh, S.

10.1101/2021.07.17.452781 — plant biology — Posted on 2021-07-20

1496 A dynamic and combinatorial histone code drives malaria parasite asexual and sexual development

von Grüning, H.; Coradin, M.; Mendoza, M.; Reader, J.; Sidoli, S.; Garcia, B.; Birkholtz, L.-M.

10.1101/2021.07.19.452879 — biochemistry — Posted on 2021-07-20

1497 Gene co-expression reveals the modularity and integration of C4 and CAM in Portulaca

Gilman, I. S.; Moreno-Villena, J. J.; Lewis, Z. R.; Goolsby, E. W.; Edwards, E. J.

10.1101/2021.07.07.451465 — evolutionary biology — Posted on 2021-07-20

1498 Intramembrane protease SPP defines a cholesterol-regulated switch of the mevalonate pathway

Heidasch, R.; Avci, D.; Lüchtenborg, C.; Kale, D.; Beard, H.; Mentrup, T.; Barniol-Xicota, M.; Schröder, B.; verhelst, S.; Brügger, B.; Lemberg, M. K.

10.1101/2021.07.19.452877 — cell biology — Posted on 2021-07-20

1499 Intrabody induced cell death by targeting the T. brucei cytoskeletal protein TbBILBO1

Broster-Reix, C. E.; Ramanantsalama, M. R.; Di Primo, C.; Minder, L.; Bonhivers, M.; Dacheux, D.; Robinson, D. R.

10.1101/2021.07.18.452872 — cell biology — Posted on 2021-07-20

1500 Rapid visual CRISPR assay: a naked-eye colorimetric detection method for nucleic acids based on CRISPR/Cas12a and convolutional neural network

Xie, S.; Tao, D.; Fu, Y.; Xu, B.; Tang, Y.; Lucilla, S.; Hanneke, H.; Pan, W.; Huang, X.; Zhao, C.; Ruan, J.; Fu, L.; Nie, X.; Zhang, Y.; Han, J.; Ma, Y.; Li, X.; Liu, X.; Zhao, S.

10.1101/2021.07.17.452802 — molecular biology — Posted on 2021-07-20

1501 Comparison of heat-inactivated and infectious SARS-CoV-2 across indoor surface materials shows comparable RT-qPCR viral signal intensity and persistence

Salido, R. A.; Cantu, V. J.; Clark, A. E.; Leibel, S. L.; Foroughishafiei, A.; Saha, A.; Hakim, A.; Nouri, A.; Lastrella, A. L.; Castro-Martinez, A.; Plascencia, A.; Kapadia, B.; Xia, B.; Ruiz, C.; Marotz, C.; Maunder, D.; Lawrence, E. S.; Smoot, E. W.; Eisner, E.; Crescini, E. S.; Kohn, L.; Franco Vargas, L.; Chacon, M.; Betty, M.; Machnicki, M.; Wu, M. Y.; Baer, N. A.; Belda-Ferre, P.; DeHoff, P.; Saever, P.; Ostrander, R. T.; Tsai, R.; Sathe, S.; Aigner, S.; Morgan, S. C.; Ngo, T. T.; Barber, T.; Cheung, W.; Carlin, A. F.; Yeo, G. W.; Laurent, L.; Fielding-Miller, R.; Knight, R.

10.1101/2021.07.16.452756 — microbiology — Posted on 2021-07-20

1502 Genomic epidemiology and strain taxonomy of Corynebacterium diphtheriae

Guglielmini, J.; Hennart, M.; Badell, E.; Toubiana, J.; Criscuolo, A.; Brisse, S.

10.1101/2021.07.18.452871 — microbiology — Posted on 2021-07-20

1503 Differences between intrinsic and acquired nucleoside analogue resistance in acute myeloid leukaemia cells

Rothenburger, T.; Thomas, D.; Schreiber, Y.; Wratil, P. R.; Pflantz, T.; Knecht, K.; Digianantonio, K.; Temple, J.; Schneider, C.; Baldauf, H.-M.; McLaughlin, K.-M.; Rothweiler, F.; Bilen, B.; Farmand, S.; Bojkova, D.; Costa, R.; Ferreiros, N.; Geisslinger, G.; Oellerich, T.; Xiong, Y.; Keppler, O. T.; Wass, M. N.; Michaelis, M.; Cinatl, J.

10.1101/2021.07.19.452885 — pharmacology and toxicology — Posted on 2021-07-20

1504 Customization of a dada2-based pipeline for fungal Internal Transcribed Spacer 1 (ITS 1) amplicon datasets

Rolling, T.; Zhai, B.; Frame, J. V.; Hohl, T.; Taur, Y.

10.1101/2021.07.19.452952 — bioinformatics — Posted on 2021-07-20

1505 Inference of polyploid origin and inheritance mode from population genomic data

Scott, A. D.; Van de Velde, J. D.; Novikova, P. Y.

10.1101/2021.07.19.452883 — genomics — Posted on 2021-07-20

1506 Spontaneous emergence of multicellular heritability

Zamani-Dahaj, S. A.; Burnetti, A.; Day, T.; Ratcliff, w. C.; Yunker, P. J.; Herron, M. D.

10.1101/2021.07.19.452990 — evolutionary biology — Posted on 2021-07-20

1507 The joint evolution of movement and competition strategies

Gupte, P. R.; Netz, C. F.; Weissing, F. J.

10.1101/2021.07.19.452886 — evolutionary biology — Posted on 2021-07-20

1508 Megasatellite formation and evolution in vertebrates

Descorps-Declere, S.; Richard, G.-F.

10.1101/2021.07.19.452908 — evolutionary biology — Posted on 2021-07-20

1509 The effect of climate change on the distribution of Canidae

Porto, L. M. V.; Bennett, D.; Maestri, R.; Etienne, R.

10.1101/2021.07.19.452957 — ecology — Posted on 2021-07-20

1510 Effects of four antibiotics on the diversity of the intestinal microbiota

Huang, C.; Feng, S.; Huo, F.; Liu, H.

10.1101/2021.07.19.453004 — microbiology — Posted on 2021-07-20

1511 Postsynaptic neuroligin-1 mediates presynaptic endocytosis during neuronal activity

Luo, J. K.; Melland, H.; Nithianantharajah, J.; Gordon, S. L.

10.1101/2021.07.20.453031 — neuroscience — Posted on 2021-07-20

1512 Diet modifies allele-specific phenotypes in Drosophila carrying epilepsy-associated PNPO variants

Chi, W.; Iyengar, A.; Fu, W.; Liu, W.; Berg, A. E.; Wu, C.-F.; Zhuang, X.

10.1101/2021.07.19.452889 — neuroscience — Posted on 2021-07-20

1513 Emergence and fragmentation of the alpha-band driven by neuronal network dynamics

Zonca, L.; Holcman, D.

10.1101/2021.07.19.452820 — neuroscience — Posted on 2021-07-20

1514 Typical and disrupted brain circuitry for conscious awareness in full-term and preterm infants

Hu, H.; Cusack, R.; Naci, L.

10.1101/2021.07.19.452937 — neuroscience — Posted on 2021-07-20

1515 Cardiac-generated sympathetic stress alters heart-brain communication, reduces EEG-theta activity, and increases locomotor behavior

Agrimi, J.; Menicucci, D.; Laurino, M.; Mackey, C.; Hasnain, L.; Dodaballapur, S.; McDevit, R. A.; Hoover, D. B.; Gemignani, A.; Paolocci, N.; Lakatta, E. G.

10.1101/2021.07.19.452502 — physiology — Posted on 2021-07-20

1516 Diisopropylfluorophosphate (DFP) volatizes and cross-contaminates wells in a common 96-well plate zebrafish larvae exposure method

Mundy, P. C.; Mendieta, R.; Lein, P. J.

10.1101/2021.07.19.452994 — pharmacology and toxicology — Posted on 2021-07-20

1517 CulebrONT: a streamlined long reads multi-assembler pipeline for prokaryotic and eukaryotic genomes

Orjuela, J.; Comte, A.; Ravel, S.; Charriat, F.; Vi, T.; Sabot, F.; Cunnac, S.

10.1101/2021.07.19.452922 — bioinformatics — Posted on 2021-07-20

1518 plantR: An R package and workflow for managing species records from biological collections

Lima, R. A. F.; Sanchez-Tapia, A.; Mortara, S. R.; Steege, H.; Siqueira, M. F.

10.1101/2021.04.06.437754 — bioinformatics — Posted on 2021-07-20

1519 CUT&Tag-BS: an efficient and low-cost method for simultaneous profiling of histone modification and DNA methylation

Li, R.; Grimm, S. A.; Wade, P.

10.1101/2021.07.19.452967 — genomics — Posted on 2021-07-20

1520 Genetic basis of enhanced stress resistance in long-lived mutants highlights key role of innate immunity in determining longevity

Soo, S.; Rudich, P.; Mistry, M.; Van Raamsdonk, J.

10.1101/2021.07.19.452975 — genetics — Posted on 2021-07-20

1521 An ancient polymorphic regulatory region within the BDNF gene associated with obesity modulates anxiety-like behaviour in mice and humans.

McEwan, A. R.; Hing, B.; Erickson, J.; Turnbull, Y.; Delibegovic, M.; Grassmann, F.; MacKenzie, A.

10.1101/2021.07.20.452916 — genetics — Posted on 2021-07-20

1522 A Bayesian model selection approach for mediation analysis

Crouse, W. L.; Keele, G. R.; Gastonguay, M. S.; Churchill, G. A.; Valdar, W.

10.1101/2021.07.19.452969 — genetics — Posted on 2021-07-20

1523 An improved auxin-inducible degron system for fission yeast

Zhang, X.-R.; Zhao, L.; Suo, F.; Gao, Y.; Wu, Q.; Qi, X.; Du, L.-L.

10.1101/2021.07.19.452993 — genetics — Posted on 2021-07-20

1524 Reticulate evolution in a neutral model: speciation, extinctions, and hybridizations

Lubiana Botelho, L.; Darcie Marquitti, F. M.; de Aguiar, M. A. M.

10.1101/2021.07.19.452966 — evolutionary biology — Posted on 2021-07-20

1525 Evolutionary Sparse Learning for phylogenomics

Kumar, S.; Sharma, S.

10.1101/2021.07.19.452974 — evolutionary biology — Posted on 2021-07-20

1526 The genetic basis of cooperation and conflict in natural populations of a model symbiont

Batstone, R. T.; Burghardt, L. T.; Heath, K. D.

10.1101/2021.07.19.452989 — evolutionary biology — Posted on 2021-07-20

1527 Spatio-temporal patterns of multi-trophic biodiversity and food-web characteristics across a river catchment

Blackman, R. C.; Ho, H.-C.; Walser, J.-C.; Altermatt, F.

10.1101/2021.07.20.450136 — ecology — Posted on 2021-07-20

1528 Paninvasion severity assessment of a US grape pest to disrupt the global wine market

Huron, N. A.; Behm, J. E.; Helmus, M. R.

10.1101/2021.07.19.452723 — ecology — Posted on 2021-07-20

1529 Ecotoxicological effects of silver nanoparticles in marine mussels

Calisi, A.; Lorusso, C.; Gallego Urrea, J. A.; Hassellov, M.; Dondero, F.

10.1101/2021.07.19.452197 — ecology — Posted on 2021-07-20

1530 The self-peptide repertoire plays a critical role in transplant tolerance induction

Son, E. T.; Faridi, P.; Paul-Heng, M.; Leong, M.; English, K.; Ramarathinam, S. H.; Braun, A.; Dudek, N.; Alexander, I. E.; Lisowski, L.; Bertolino, P.; Bowen, D.; Purcell, A. W.; Mifsud, N.; Sharland, A. F.

10.1101/2020.11.09.359968 — immunology — Posted on 2021-07-20

1531 Plasticity of the dopaminergic phenotype and of locomotion in larval zebrafish induced by changes in brain excitability during the embryonic period.

Bataille, S.; Jalaber, H.; Colin, I.; Remy, D.; Affaticati, P.; Froc, C.; Vernier, P.; Demarque, M.

10.1101/2021.07.19.452915 — neuroscience — Posted on 2021-07-20

1532 Prenatal androgen treatment does not alter the firing activity of hypothalamic arcuate kisspeptin neurons in female mice

Gibson, A. G.; Jaime, J.; Burger, L. L.; Moenter, S. M.

10.1101/2021.07.19.452845 — neuroscience — Posted on 2021-07-20

1533 Differential stimulation of pluripotent stem cell-derived human microglia leads to exosomal proteomic changes affecting neurons

Mallach, A.; Gobom, J.; Arber, C.; Piers, T. M.; Hardy, J.; Wray, S.; Zetterberg, H.; Pocock, J. M.

10.1101/2021.07.19.452610 — neuroscience — Posted on 2021-07-20

1534 Distinct but cooperating brain networks supporting semantic cognition

Jung, J.; Lambon Ralph, M. A.

10.1101/2021.07.19.452716 — neuroscience — Posted on 2021-07-20

1535 Connectivity and dynamics in the olfactory bulb

Kersen, D. E.; Tavoni, G.; Balasubramanian, V.

10.1101/2021.07.19.452784 — neuroscience — Posted on 2021-07-20

1536 Specialized neurons in the right habenula mediate response to aversive olfactory cues

Halpern, M. E.; Choi, J.-H.; Duboue, E.; Macurak, M.; Chanchu, J.-M.

10.1101/2021.07.19.452986 — neuroscience — Posted on 2021-07-20

1537 Residual dynamics resolves recurrent contributions to neural computation

Galgali, A. R.; Sahani, M.; Mante, V.

10.1101/2021.07.19.452951 — neuroscience — Posted on 2021-07-20

1538 Losartan shifts social reward motivation and punishment feedback sensitivity via modulating midbrain-striato-frontal circuits

Zhou, X.; Xu, T.; Zeng, Y.; Zhang, R.; Qi, Z.; Zhao, W.; Kendrick, K. M.; Becker, B.

10.1101/2021.07.19.452920 — neuroscience — Posted on 2021-07-20

1539 Global distribution and diversity of alien Ponto-Caspian amphipods

Copilas-Ciocianu, D.; Sidorov, D.; Sidagyte-Copilas, E.

10.1101/2021.07.19.452907 — zoology — Posted on 2021-07-20

1540 Hyperspectral characterisation of natural illumination in woodland and forest environments

Shiwen, L.; Steel, L.; Dahlsjö, C. A. L.; Peirson, S. N.; Shenkin, A.; Morimoto, T.; Smithson, H. E.; Spitschan, M.

10.1101/2021.07.19.452949 — systems biology — Posted on 2021-07-20

1541 As potential biomarkers, kinetic network features may be more predictive than molecule abundances

Hoffmann, A.; Loriaux, P.; Tang, Y.

10.1101/2021.07.19.452900 — systems biology — Posted on 2021-07-20

1542 CHOmpact: a reduced metabolic model of Chinese hamster ovary cells with enhanced interpretability

Jimenez del Val, I.; Kyriakopoulos, S.; Albrecht, S.; Stöckmann, H.; Rudd, P. M.; Polizzi, K. M.; Kontoravdi, C.

10.1101/2021.07.19.452953 — systems biology — Posted on 2021-07-20

1543 Bayesian optimisation for yield in high-dimensional trait-space identifies crop ideotypes in Oil Seed Rape

Calderwood, A.; Siles Suarez, L.; Eastmond, P. J.; Kurup, S.; Morris, R. J.

10.1101/2021.07.19.452946 — plant biology — Posted on 2021-07-20

1544 Identification of green lineage osmotic stress pathways

Vilarrasa-Blasi, J.; Vellosillo, T.; Jinkerson, R. E.; Fauser, F.; Xiang, T.; Minkoff, B. B.; Wang, L.; Kniazev, K.; Guzman, M.; Osaki, J.; Sussman, M. R.; Jonikas, M. C.; Dinneny, J. R.

10.1101/2021.07.19.453009 — plant biology — Posted on 2021-07-20

1545 Energetics but not development is impacted in coral embryos exposed to ocean acidification

Chille, E. E.; Strand, E. L.; Scucchia, F.; Schmidt, V.; Neder, M.; Sherman, M. O.; Mass, T.; Putnam, H. M.

10.1101/2021.07.19.452948 — physiology — Posted on 2021-07-20

1546 A New Proposal of an Index for Regional Cerebral Perfusion Pressure - A Theoretical Approach with Fluid Dynamics

Kameyama, M.; Momose, T.

10.1101/2021.07.18.452866 — physiology — Posted on 2021-07-20

1547 Profiling of human neural crest chemoattractant activity as replacement of fetal bovine serum for in vitro chemotaxis assays

Dolde, X.; Karreman, C.; Wiechers, M.; Schildknecht, S.; Leist, M.

10.1101/2021.07.19.452897 — pharmacology and toxicology — Posted on 2021-07-20

1548 Tissue-Specific Biochemical Differences Between Chronic Wasting Disease Prions Isolated From Free Ranging, White-Tailed Deer (Odocoileus virginianus)

Wagner, K.; Pierce, R.; Gordon, E.; Ballard, J. R.; Moreno, J. A.; Zabel, M. D.

10.1101/2021.07.19.452961 — pathology — Posted on 2021-07-20

1549 Fighting cancer with oncolytic viral therapy: identifying threshold parameters for success

Jahedi, S.; Wang, L.; Watmough, J.

10.1101/2021.07.19.452846 — cancer biology — Posted on 2021-07-20

1550 A Quantitative Paradigm for Water Assisted Proton Transport Through Proteins and Other Confined Spaces

Li, C.; Voth, G. A.

10.1101/2021.07.19.452976 — biophysics — Posted on 2021-07-20

1551 Absolute copy number fitting from shallow whole genome sequencing data

Sauer, C. M.; Eldridge, M. D.; Vias, M.; Hall, J. A.; Boyle, S. E.; Macintyre, G.; Bradley, T.; Markowetz, F.; Brenton, J. D.

10.1101/2021.07.19.452658 — bioinformatics — Posted on 2021-07-20

1552 Cell minor-axis length is a critical feature for breast cancer cell migration on straight, wavy, loop and grid microfibre patterns

Zhang, D.; Sheng, Y.; Piano, N.; Jakuszeit, T.; Cozens, E.; Dong, L.; Lei, I. M.; Wang, A.; Terentjev, E. M.; Huang, Y. Y. S.

10.1101/2021.07.19.452928 — bioengineering — Posted on 2021-07-20

1553 Construction of functional biliary epithelial branched networks with predefined geometry using digital light stereolithography

Mazari-Arrighi, E.; Ayollo, D.; Farhat, W.; Marret, A.; Gontran, E.; Dupuis-Williams, P.; Larghero, J.; Chatelain, F.; Fuchs, A.

10.1101/2021.07.19.452904 — bioengineering — Posted on 2021-07-20

1554 Data-Driven Strain Design Using Aggregated Adaptive Laboratory Evolution Mutational Data

Phaneuf, P. V.; Zielinski, D. C.; Yurkovich, J. T.; Johnsen, J.; Szubin, R.; Yang, L.; Kim, S. H.; Schulz, S.; Wu, M.; Dalldorf, C.; Ozdemir, E.; Palsson, B. O.; Feist, A.

10.1101/2021.07.19.452699 — bioengineering — Posted on 2021-07-20

1555 Genomic insights into the differentiated population admixture structure and demographic history of North East Asians

He, G.; Wang, M.; Zou, X.; Tang, R.; Yeh, H.-Y.; Wang, Z.; Yang, X.; Xia, Z.; Li, Y.; Guo, J.; Wang, R.; Liu, J.; Zhu, K.; Chen, J.; Yang, M.; Shen, Q.; Chen, J.; Zhao, J.; Ma, H.; Wei, L.; Chen, L.; Liu, C.; Liu, C.; Chen, G.; Hou, Y.; Wang, C.-C.

10.1101/2021.07.19.452943 — genomics — Posted on 2021-07-20

1556 Application of personalized differential expression analysis in human cancer proteome

Liu, Y.; Lin, Y.; Wu, Y.; Zhang, Z.; Tong, M.; Yu, R.

10.1101/2021.07.18.452812 — bioinformatics — Posted on 2021-07-20

1557 Prior Signal Acquisition Software Versions for Orbitrap Underestimate Low Isobaric Mass Tag Intensities, Without Detriment to Differential Abundance Experiments

Smith, T. S.; Andrejeva, A.; Christopher, J. A.; Crook, O. M.; Elzek, M. A. W.; Lilley, K. S.

10.1101/2021.07.18.452841 — bioinformatics — Posted on 2021-07-20

1558 High resolution dynamic mapping of the C. elegans intestinal brush border

Bidaud-Meynard, A.; Demouchy, F.; Nicolle, O.; Pacquelet, A.; Suman, S. K.; Plancke, C.; ROBIN, F. B.; Michaux, G.

10.1101/2021.06.14.448317 — developmental biology — Posted on 2021-07-20

1559 Homeostatic brain network mechanisms facilitate perceptual binding of audio-visual speech

Mukherjee, A.; Singh, S. S.; Ray, D.; Raghunathan, P.; Banerjee, A.

10.1101/2020.09.02.276071 — neuroscience — Posted on 2021-07-20

1560 Traces of semantization - from episodic to semantic memory in a spiking cortical network model

Chrysanthidis, N.; Fiebig, F.; Lansner, A.; Herman, P.

10.1101/2021.07.18.452769 — neuroscience — Posted on 2021-07-20

1561 Pre-trauma memory contextualization as predictor for PTSD-like behavior in male rats

Sep, M. S. C.; Sarabdjitsingh, R. A.; Geuze, E.; Joels, M.

10.1101/2021.07.17.452780 — neuroscience — Posted on 2021-07-20

1562 NOMA: a high-throughput microchip for robust, sequential measurements of secretions from the same single-cells

Liu, M.; Ji, Y.; Zhu, F.; Bai, X.; Li, L.; Xie, H.; Liu, X.; Luo, Y.; Liu, T.; Lin, B.; Lu, Y.

10.1101/2021.01.21.427049 — bioengineering — Posted on 2021-07-20

1563 Analysis of eukaryotic lincRNA sequences reveals signatures of repressed translation in species under strong selection

Brümmer, A.; Dreos, R.; Marques, A. C.; Bergmann, S.

10.1101/737890 — genomics — Posted on 2021-07-20

1564 Multi-regional module-based signal transmission in mouse visual cortex

Jia, X.; Siegle, J. H.; Durand, S.; Heller, G.; Ramirez, T.; Koch, C.; Olsen, S. R.

10.1101/2020.08.30.272948 — neuroscience — Posted on 2021-07-20

1565 Network expansion of genetic associations defines a pleiotropy map of human cell biology

Barrio-Hernandez, I.; Schwartzentruber, J.; Shrivastava, A.; del Toro, N.; Zhang, Q.; Bradley, G.; Hermjakob, H.; Orchard, S.; Dunham, I.; Anderson, C. A.; Porras, P.; Beltrao, P.

10.1101/2021.07.19.452924 — genetics — Posted on 2021-07-19

1566 Mitochondrial Respiratory Chain Protein Co-Regulation in the Human Brain

Trumpff, C.; Owusu-Ansah, E.; Klein, H.-U.; Lee, A.; Petyuk, V.; Wingo, T. S.; Wingo, A.; Thambisetty, M.; Ferrucci, L.; Seyfried, N.; Bennett, D. A.; De Jager, P. L.; Picard, M.

10.1101/2021.07.19.452923 — cell biology — Posted on 2021-07-19

1567 The amplitude of fNIRS hemodynamic response in the visual cortex unmasks autistic traits in typically developing children

Mazziotti, R. M.; Scaffei, E.; Conti, E.; Marchi, V.; Rizzi, R.; Battini, R.; Cioni, G.; Baroncelli, L.

10.1101/2021.07.19.452678 — neuroscience — Posted on 2021-07-19

1568 The zebra finch auditory cortex reconstructs occluded syllables in conspecific song

Bjoring, M. C.; Meliza, C. D.

10.1101/2021.07.19.452925 — neuroscience — Posted on 2021-07-19

1569 Quantification of spatial subclonal interactions enhancing the invasive phenotype of paediatric glioma

Tari, H.; Kessler, K.; Trahearn, N.; Werner, B.; Vinci, M.; Jones, C.; Sottoriva, A.

10.1101/2021.07.19.452844 — cancer biology — Posted on 2021-07-19

1570 Inhibitory proteins block substrate access to the membrane-embedded active site of Bacillus subtilis intramembrane metalloprotease SpoIVFB

Olenic, S.; Heo, L.; Feig, M.; Kroos, L.

10.1101/2021.07.09.451828 — biochemistry — Posted on 2021-07-19

1571 Malignancy and NF-kB signalling strengthen coordination between the expression of mitochondrial and nuclear-encoded oxidative phosphorylation genes

Perez, M. F.; Sarkies, P.

10.1101/2021.06.30.450588 — genomics — Posted on 2021-07-19

1572 Evaluation of DNA extraction protocols from liquid-based cytology specimens for studying cervical microbiota

Shibata, T.; Nakagawa, M.; Coleman, H. N.; Owens, S. M.; Greenfield, W. W.; Sasagawa, T.; Robeson, M. S.

10.1101/2020.01.27.921619 — microbiology — Posted on 2021-07-19

1573 Epigenetic modulation of selected immune response genes and altered functions of T lymphocytes and macrophages collectively contribute to autoimmune diabetes protection.

Jayaraman, S.; Arianas, M.; Jayaraman, A.

10.1101/2021.07.15.452572 — immunology — Posted on 2021-07-19

1574 The ASC Speck And NLRP3 Inflammasome Function Are Spatially And Temporally Distinct

Harton, J.; Nagar, A.; Rahman, T.

10.1101/2021.07.19.452947 — immunology — Posted on 2021-07-19

1575 Separable neural signatures of confidence during perceptual decisions

Balsdon, T.; Mamassian, P.; Wyart, V.

10.1101/2021.04.08.439033 — neuroscience — Posted on 2021-07-19

1576 Robust and tunable signal processing in mammalian cells via engineered covalent modification cycles

Jones, R. D.; Qian, Y.; Ilia, K.; Wang, B.; Laub, M. T. T.; Del Vecchio, D.; Weiss, R.

10.1101/2021.03.30.437779 — synthetic biology — Posted on 2021-07-19

1577 Ultra-lightweight living structural material for enhanced stiffness and environmental sensing

Park, H.; Schwartzman, A. F.; Tang, T.-C.; Wang, L.; Lu, T. K.

10.1101/2021.07.19.452887 — synthetic biology — Posted on 2021-07-19

1578 Singlet oxygen leads to structural changes to chloroplasts during degradation in the Arabidopsis thaliana plastid ferrochelatase two mutant

Fisher, K. E.; Krishnamoorthy, P.; Joens, M. S.; Chory, J.; Fitzpatrick, J. A. J.; Woodson, J. D.

10.1101/2021.07.19.452378 — plant biology — Posted on 2021-07-19

1579 Chemical inhibition of lycopene β-cyclases unmask operation of phytoene synthase 2 in ripening tomato fruits

Gupta, P.; Rodriguez-Franco, M.; Bodanapu, R.; Sreelakshmi, Y.; Sharma, R.

10.1101/2021.07.19.452896 — plant biology — Posted on 2021-07-19

1580 SOX4 facilitates PGR protein stability and FOXO1 expression conducive for human endometrial decidualization

Wang, H.; Huang, P.; Deng, W.; Bao, H.; Lin, Z.; Liu, M.; Wu, J.; Zhou, X.; Qiao, M.; Yang, Y.; Cai, H.; Rao, F.; Chen, J.; Chen, D.; Lu, J.; Qin, A.; Kong, S.

10.1101/2021.07.19.452960 — physiology — Posted on 2021-07-19

1581 A novel nanoluciferase transgenic reporter to measure proteinuria in zebrafish

Naylor, R. W. W.; Lemarie, E.; Jackson-Crawford, A.; Davenport, J. B.; Mironov, A.; Lowe, M.; Lennon, R.

10.1101/2021.07.19.452884 — pathology — Posted on 2021-07-19

1582 Approximation of the age distribution of cancer incidence using a mutational model

Tetearing, A. N.

10.1101/2021.07.06.451349 — cancer biology — Posted on 2021-07-19

1583 Predicting the Conformational Variability of Oncogenic GTP-bound G12D Mutated KRas-4B Proteins at Cell Membranes

Lu, H.; Marti, J.

10.1101/2021.07.19.452936 — biophysics — Posted on 2021-07-19

1584 Comparison of linear combination modeling strategies for GABA-edited MRS at 3T

Zöllner, H. J.; Tapper, S.; Hui, S. C. N.; Barker, P. B.; Edden, R. A. E.; Oeltzschner, G.

10.1101/2021.05.26.445817 — biochemistry — Posted on 2021-07-19

1585 Complete genomic and epigenetic maps of human centromeres

Altemose, N.; Logsdon, G. A.; Bzikadze, A. V.; Sidhwani, P.; Langley, S. A.; Caldas, G. V.; Hoyt, S. J.; Uralsky, L.; Ryabov, F. D.; Shew, C. J.; Sauria, M. E. G.; Borchers, M.; Gershman, A.; Mikheenko, A.; Shepelev, V. A.; Dvorkina, T.; Kunyavskaya, O.; Vollger, M. R.; Rhie, A.; McCartney, A. M.; Asri, M.; Lorig-Roach, R.; Shafin, K.; Aganezov, S.; Olson, D.; Gomes de Lima, L.; Potapova, T.; Hartley, G. A.; Haukness, M.; Kerpedjiev, P.; Gusev, F.; Tigyi, K.; Brooks, S.; Young, A.; Nurk, S.; Koren, S.; Salama, S. R.; Paten, B.; Rogaev, E. I.; Streets, A.; Karpen, G. H.; Dernburg, A. F.; Sulliv

10.1101/2021.07.12.452052 — genomics — Posted on 2021-07-19

1586 Regulation by Progestins, Corticosteroids and RU486 of Activation of Elephant Shark and Human Progesterone Receptors: An Evolutionary Perspective

Lin, X.; Takagi, W. T.; Hyodo, S.; Ijiri, S.; Katsu, Y. K.; Baker, M. E.

10.1101/2021.01.20.427507 — evolutionary biology — Posted on 2021-07-19

1587 No evidence for dominance-discovery tradeoffs in Pheidole (Hymenoptera: Formicidae) assemblages

Klunk, C. L.; Pie, M. R.

10.1101/2020.05.20.106864 — ecology — Posted on 2021-07-19

1588 A high-throughput assay for directly monitoring nucleolar rRNA biogenesis

Bryant, C. J.; McCool, M. A.; Abriola, L.; Surovtseva, Y. V.; Baserga, S. J.

10.1101/2021.07.19.452935 — cell biology — Posted on 2021-07-19

1589 Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics

Basu, S.; Shukron, O.; Hall, D.; Parruto, P.; Ponjavic, A.; Shah, D.; Boucher, W.; Lando, D.; Zhang, W.; Reynolds, N.; Sober, L. H.; Jartseva, A.; Ragheb, R.; Ma, X.; Cramard, J.; Floyd, R.; Brown, G.; Balmer, J.; Drury, T. A.; Carr, A.; Needham, L.-M.; Aubert, A.; Communie, G.; Gor, K.; Steindel, M.; Morey, L.; Blanco, E.; Bartke, T.; Di Croce, L.; Berger, I.; Schaffitzel, C.; Lee, S.; Stevens, T. J.; Klenerman, D.; Hendrich, B.; Holcman, D.; Laue, E. D.

10.1101/2020.04.03.003178 — cell biology — Posted on 2021-07-19

1590 Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy

Eapen, V.; Swarup, S.; Hoyer, M. J.; Paulo, J. A.; Harper, J. W.

10.1101/2021.07.19.452535 — cell biology — Posted on 2021-07-19

1591 Small-molecule cocktails induce the differentiation of human adipose-derived mesenchymal stem cells into hepatocyte-like cells

Yin, K.; Xu, Y.; Wu, D.; Yang, W.; Dong, N.; Li, N.; Zhao, R. C.

10.1101/2021.07.19.452852 — cell biology — Posted on 2021-07-19

1592 Longitudinal tracking reveals sustained polyclonal repopulation of human-HSPC in humanized mice despite vector integration bias

Suryawanshi, G. W.; Arokium, H.; Kim, S.; Khamaikawin, W.; Lin, S.; Shimizu, S.; Chupradit, K.; Lee, Y.; Xie, Y.; Guan, X.; Suryawanshi, V.; Presson, A. P.; An, D.-S.; Chen, I. S. Y.

10.1101/2020.08.21.261537 — molecular biology — Posted on 2021-07-19

1593 A unified evolutionary origin for the ubiquitous protein transporters SecY and YidC

Lewis, A. J. O.; Hegde, R. S.

10.1101/2020.12.20.422553 — molecular biology — Posted on 2021-07-19

1594 Structural model of PORCN illuminates disease-associated variants and drug binding sites

Yu, J.; Liao, P.-J.; Xu, W.; Jones, J. R.; Everman, D. B.; Flanagan-Steet, H.; Keller, T. H.; Virshup, D. M.

10.1101/2021.07.19.452875 — molecular biology — Posted on 2021-07-19

1595 Key substitutions in the spike protein of SARS-CoV-2 variants can predict resistance to monoclonal antibodies, but other substitutions can modify the effects

Lusvarghi, S.; Wang, W.; Herrup, R.; Neerukonda, S. N.; Vassell, R.; Bentley, L.; Eakin, A. E.; Erlandson, K. J.; Weiss, C. D.

10.1101/2021.07.16.452748 — microbiology — Posted on 2021-07-19

1596 Pathotyping of Newcastle disease virus: A novel single BsaHI digestion method of detection and differentiation of avirulent strains (lentogenic and mesogenic vaccine strains) from virulent virus

Desingu, P. A.; Singh, S. D.; Dhama, K.; Vinodhkumar, O. R.; Nagarajan, K.; Singh, R.; Malik, Y. S.; Singh, R. K.

10.1101/2021.07.16.452760 — microbiology — Posted on 2021-07-19

1597 Self-sensitisation of Staphylococcus aureus to the antimicrobial factors found in human blood.

Douglas, E.; Brignoli, T.; Recker, M.; O'Brien, E.; McLoughlin, R.; Massey, R. C.

10.1101/2021.07.19.452914 — microbiology — Posted on 2021-07-19

1598 Multi-substrate DNA stable isotope probing reveals guild structure in bacterially mediated soil carbon cycling

Barnett, S. E.; Youngblut, N. D.; Koechli, C. N.; Buckley, D. H.

10.1101/2021.03.19.436178 — microbiology — Posted on 2021-07-19

1599 Granulocyte-colony stimulating factor (G-CSF) enhances cocaine effects in the nucleus accumbens via a dopamine release-based mechanism

Brady, L. J.; Erickson, K. R.; Lucerne, K. E.; Osman, A.; Kiraly, D. D.; Calipari, E. S.

10.1101/2021.07.19.452968 — neuroscience — Posted on 2021-07-19

1600 Efficient Spline Regression for Neural Spiking Data

Sarmashghi, M.; Jadhav, S. P.; Eden, U.

10.1101/2020.09.01.276105 — neuroscience — Posted on 2021-07-19

1601 The vesicular release probability sets the strength of individual Schaffer collateral synapses

Duerst, C. D.; Wiegert, J. S.; Schulze, C.; Helassa, N.; Torok, K.; Oertner, T. G.

10.1101/2020.08.02.232850 — neuroscience — Posted on 2021-07-19

1602 Breathing Behaviors in Common Marmoset (Callithrix jacchus)

Bishop, M.; Turk, A. Z.; Adeck, A.; SheikhBahaei, S.

10.1101/2020.07.27.223990 — neuroscience — Posted on 2021-07-19

1603 Robust and efficient online auditory psychophysics with the right auditory hygiene

Zhao, S.; Brown, C. A.; Holt, L. L.; Dick, F.

10.1101/2021.07.17.452796 — neuroscience — Posted on 2021-07-19

1604 Frontoparietal pattern similarity analyses of cognitive control in monozygotic twins

Tang, R.; Etzel, J. A.; Kizhner, A.; Braver, T. S.

10.1101/2020.11.19.390492 — neuroscience — Posted on 2021-07-19

1605 Cellular and behavioral effects of altered NaV1.2 sodium channel ion permeability in Scn2aK1422E mice

Echevarria-Cooper, D. M.; Hawkins, N. A.; Misra, S. N.; Huffman, A.; Thaxton, T.; Thompson, C. H.; Ben-Shalom, R.; Nelson, A. D.; Lipkin, A. M.; George, A. L.; Bender, K. J.; Kearney, J. A.

10.1101/2021.07.19.452930 — neuroscience — Posted on 2021-07-19

1606 Autophagic signaling promotes systems-wide remodeling in skeletal muscle upon oncometabolic stress

Karlstaedt, A.; Vitrac, H.; Salazar, R. L.; Gould, B. D.; Soedkamp, D.; Spivia, W.; Raedschelders, K.; Dinh, A. Q.; Guzman, A.; Tan, L.; Azinas, S.; Taylor, D. J. R.; Schiffer, W.; McNavish, D.; Burks, H. B.; Gottlieb, R. A.; Lorenzi, P. L.; Hanson, B.; Van Eyk, J. E.; Taegtmeyer, H.

10.1101/2020.10.13.338202 — systems biology — Posted on 2021-07-19

1607 Redox regulation by TXNRD3 during epididymal maturation underlies capacitation-associated mitochondrial activation and sperm motility in mice

Wang, H.; Dou, Q.; Jung, K. J.; Choi, J.; Gladyshev, V. N.; Chung, J.-J.

10.1101/2021.07.19.452987 — physiology — Posted on 2021-07-19

1608 Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance

Skovso, S.; Panzhinskiy, E.; Kolic, J.; Cen, H. H.; Dionne, D. A.; Dai, X.-Q.; Sharma, R. B.; Elghazi, L.; Ellis, C. E.; Faulkner, K.; Marcil, S. A. M.; Overby, P.; Noursadeghi, N.; Hutchinson, D.; Hu, X.; Modi, H.; Wildi, J.; Botezelli, J. D.; Noh, H. L.; Suk, S.; Gablaski, B.; Bautista, A.; Kim, R.; Cras-Meneur, C.; Flibotte, S.; Sinha, S.; Luciani, D. S.; Nislow, C.; Rideout, E. J.; Cytrynbaum, E. N.; Kim, J.; Bernal-Mizrachi, E.; Alonso, L. C.; MacDonald, P. E.; Johnson, J. D.

10.1101/2020.10.15.338160 — physiology — Posted on 2021-07-19

1609 OSTEOPONTIN DEFICIENCY LEADS TO THE RESOLUTION OF PROSTATIC FIBROSIS AND INFLAMMATION

Popovics, P.; Jain, A.; Skalitzky, K. O.; Schroeder, E.; Ruetten, H. M.; Cadena, M.; Uchtmann, K. S.; Vezina, C. M.; Ricke, W. A.

10.1101/2021.07.19.452973 — pathology — Posted on 2021-07-19

1610 The long non-coding RNA H19 drives the proliferation of diffuse intrinsic pontine glioma with H3K27 mutation

Crea, F.

10.1101/2021.07.19.452516 — cancer biology — Posted on 2021-07-19

1611 Gata2a maintains cebpa and npm1a in haematopoietic stem cells to sustain lineage differentiation and genome stability

Mahony, C.; Noyvert, B.; Vrljicak, P.; Ott, S.; Higgs, M.; Monteiro, R.

10.1101/2021.07.19.452890 — cancer biology — Posted on 2021-07-19

1612 Loss of the H4 lysine methyltransferase KMT5B drives tumorigenic phenotypes by depleting H3K27me3 at loci otherwise retained in H3K27M mutant DIPG cells

Kessler, K.; Mackay, A.; Grabovska, Y.; Molinari, V.; Burford, A.; Temelso, S.; Tari, H.; Yara-Romero, E.; Liu, I.; Yu, L.; Castel, D.; Choudhary, J.; Sottoriva, A.; Filbin, M.; Vinci, M.; Jones, C.

10.1101/2021.07.19.452493 — cancer biology — Posted on 2021-07-19

1613 The role of the first transmembrane helix in bacterial YidC: Insights from the crystal structure and molecular dynamics simulations

Nass, K. J.; Ilie, I. M.; Saller, M. J.; Driessen, A. J. M.; Caflisch, A.; Kammerer, R. A.; Li, X.

10.1101/2021.07.15.452481 — biophysics — Posted on 2021-07-19

1614 Sense the Moment: a highly sensitive antimicrobial activity predictor based on hydrophobic moment

Porto, W. F.; Ferreira, K. C. d. V.; Ribeiro, S. M.; Franco, O. L.

10.1101/2020.07.15.205419 — bioinformatics — Posted on 2021-07-19

1615 Genetic demultiplexing of pooled single-cell RNA-sequencing samples in cancer facilitates effective experimental design

Weber, L. M.; Hippen, A. A.; Hickey, P. F.; Berrett, K. C.; Gertz, J.; Doherty, J. A.; Greene, C. S.; Hicks, S. C.

10.1101/2020.11.06.371963 — bioinformatics — Posted on 2021-07-19

1616 Optimal balancing of clinical factors in large scale clinical RNA-Seq studies

CHIANG, A. W. T.; Gazestani, V. H.; Altieri, M. G.; Kellman, B. P.; Nalabolu, S. P.; Pramparo, T.; Pierce, K.; Courchesne, E.; Lewis, N. E.

10.1101/2021.06.30.450639 — bioinformatics — Posted on 2021-07-19

1617 Characterization of vaginal microbial enzymes identifies amylopullulanases that support growth of Lactobacillus crispatus on glycogen

Woolston, B. M.; Jenkins, D. J.; Hood-Pishchany, M. I.; Rakoff-Nahoum, S.; Balskus, E. P.

10.1101/2021.07.19.452977 — biochemistry — Posted on 2021-07-19

1618 AKT1 mediates multiple phosphorylation events that functionally promote HSF1 activation

Lu, W.-C.; Omari, R.; Ray, H.; Williams, I.; Jacobs, C.; Hockaden, N.; Bochman, M. L.; Carpenter, R. L.

10.1101/2020.08.31.275909 — biochemistry — Posted on 2021-07-19

1619 Edge strand of Escherichia coli BepA interacts with immature LptD on the β-barrel assembly machine to direct it to on- and off-pathways

Miyazaki, R.; Watanabe, T.; Yoshitani, K.; Akiyama, Y.

10.1101/2021.03.28.437416 — biochemistry — Posted on 2021-07-19

1620 Genomics-based deconvolution of multiplexed transcriptional responses to wood smoke particles defines rapid AHR signaling dynamics.

Gupta, A.; Sasse, S. K.; Sanford, L.; Gruca, M. A.; Dowell, R. D.; Gerber, A. N.

10.1101/2021.02.23.432311 — genomics — Posted on 2021-07-19

1621 Understanding patterns of HIV multi-drug resistance through models of temporal and spatial drug heterogeneity

Feder, A. F.; Harper, K. N.; Brumme, C. J.; Pennings, P. S.

10.1101/807560 — evolutionary biology — Posted on 2021-07-19

1622 Host phylogeny drives the structure and diversity of insect microbiota

Malacrino', A.

10.1101/2021.07.19.452888 — ecology — Posted on 2021-07-19

1623 Intergenerational Effects of Early Life Starvation on Life-History, Consumption, and Transcriptome of a Holometabolous Insect

Paul, S. C.; Singh, P.; Dennis, A.; Mueller, C.

10.1101/2021.03.11.434967 — ecology — Posted on 2021-07-19

1624 Single-nucleus cross-tissue molecular reference maps to decipher disease gene function

Eraslan, G.; Drokhlyansky, E.; Anand, S.; Subramanian, A.; Fiskin, E.; Slyper, M.; Wang, J.; Van Wittenberghe, N.; Rouhana, J. M.; Waldman, J.; Ashenberg, O.; Dionne, D.; Win, T. S.; Cuoco, M. S.; Kuksenko, O.; Branton, P. A.; Marshall, J. L.; Greka, A.; Getz, G.; Segre, A. V.; Aguet, F.; Rozenblatt-Rosen, O.; Ardlie, K. G.; Regev, A.

10.1101/2021.07.19.452954 — cell biology — Posted on 2021-07-19

1625 Quantitative single molecule RNA-FISH and RNase-free cell wall digestion in Neurospora crassa.

Bartholomai, B.; Gladfelter, A. S.; Loros, J. J.; Dunlap, J. C.

10.1101/2021.07.19.452999 — cell biology — Posted on 2021-07-19

1626 Single-cell RNA Sequencing Reveals the Temporal Diversity and Dynamics of Cardiac Immunity after Myocardial Infarction

Jin, K.; Gao, S.; Yang, P.; Guo, R.; Li, D.; Zhang, Y.; Lu, X.; Fan, G.; Fan, X.

10.1101/2021.07.19.452902 — cell biology — Posted on 2021-07-19

1627 Dickeya solani D s0432-1 produces an arsenal of secondary metabolites with anti-prokaryotic and anti-eukaryotic activities against bacteria, yeasts, fungi, and aphids.

Effantin, G.; Brual, T.; Rahbé, Y.; Hugouvieux-Cotte-Pattat, N.; Gueguen, E.

10.1101/2021.07.19.452942 — microbiology — Posted on 2021-07-19

1628 Rosin Soap Exhibits Virucidal Activity

Bell, S.; Fairley, D. J.; Kettunen, H.; Vuorenmaa, J.; Orte, J.; Bamford, C. G. G.; McGrath, J.

10.1101/2021.07.19.452918 — microbiology — Posted on 2021-07-19

1629 Humidity Reduces Rapid and Distant Airborne Dispersal of Viable Viral Particles in Classroom Settings

Skanata, A.; Spagnolo, F.; Metz, M.; Smyth, D. S.; Dennehy, J. J.

10.1101/2021.06.22.449435 — microbiology — Posted on 2021-07-19

1630 Comparison of Neutralizing Antibody Titers Elicited by mRNA and Adenoviral Vector Vaccine against SARS-CoV-2 Variants

Tada, T.; Zhou, H.; Samanovic, M. I.; Dcosta, B. M.; Cornelius, A.; Mulligan, M. J.; Landau, N. R.

10.1101/2021.07.19.452771 — immunology — Posted on 2021-07-19

1631 TGF--dependent Lymphoid Tissue Residency of Stem-like T cells Limits the Response to Tumor Vaccine

Li, G.; Wang, L.; Ma, C.; Liao, W.; Liu, Y.; Mishra, S.; Zhang, X.; Qiu, Y.; Lu, Q.; Zhang, N.

10.1101/2021.07.19.452945 — immunology — Posted on 2021-07-19

1632 Single-dose respiratory mucosal delivery of next-generation viral-vectored COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2

Afkhami, S.; D'Agostino, M. R.; Zhang, A.; Stacey, H. D.; Marzok, A.; Kang, A.; Singh, R.; Bavananthasivam, J.; Ye, G.; Luo, X.; Wang, F.; Ang, J. C.; Zganiacz, A.; Sankar, U.; Kazhdan, N.; Koenig, J. F. E.; Phelps, A.; Jordana, M.; Wan, Y.; Mossman, K. L.; Jeyanathan, M.; Gillgrass, A.; Medina, M. F. C.; Smaill, F.; Lichty, B. D.; Miller, M. S.; Xing, Z.

10.1101/2021.07.16.452721 — immunology — Posted on 2021-07-19

1633 Xenogeneic Fibroblasts Inhibit The Growth Of Breast And Ovarian Cancer Cell Lines In Co-Culture

Usha, L.; Klapko, O.; Edassery, S.

10.1101/2021.07.19.452126 — cancer biology — Posted on 2021-07-19

1634 Unveiling Mutation Effects on the Structural Dynamics of the Main Protease from SARS-CoV-2 with Hybrid Simulation Methods

Philot, E. A.; Gasparini, P.; de Mattos, J. C.; Magro, A.; Torres-Bonfim, E.; Quiroz, R. C. N.; Klioussof, A.; Perahia, D.; Scott, A. L. B.

10.1101/2021.07.17.452787 — biophysics — Posted on 2021-07-19

1635 Artificial Intelligence-rationalized balanced PPARα/γ dual agonism resets the dysregulated macrophage processes in inflammatory bowel disease

Katkar, G.; Sayed, I. M.; Amandachar, M.; Castillo, V.; Vidales, E.; Toobian, D.; Usmani, F. F.; Sawires, J. R.; Leriche, G.; Yang, J.; Sandborn, W. J.; Das, S.; Sahoo, D.; Ghosh, P.

10.1101/2021.07.18.452807 — bioinformatics — Posted on 2021-07-19

1636 The Role of Context Conditioning in the Reinstatement of Responding to an Alcohol-Predictive Conditioned Stimulus

LeCocq, M. R.; Sun, S.; Chaudhri, N.

10.1101/2021.07.19.450216 — animal behavior and cognition — Posted on 2021-07-19

1637 Identification of Novel Long non-coding RNAs and Expression Analyses in Rectal Neuroendocrine Tumors

Padwal, M. K.; Basu, B.

10.1101/2021.07.18.452620 — genomics — Posted on 2021-07-19

1638 Real-time genomic surveillance during the 2021 re-emergence of the yellow fever virus in Rio Grande do Sul State, Brazil

Andrade, M. d. S.; Campos, F. S.; Campos, A. A. S.; Abreu, F. V. S. d.; Melo, F. L.; Cardoso, J. d. C.; Santos, E. d.; Born, L. C.; Silva, C. M. D. d.; Muller, N. F. D.; Oliveira, C. H. d.; Silva, A. J. J. d.; Simonini-Teixeira, D.; Bernal-Valle, S.; Mares-Guia, M. A.; Albuquerque, G. R.; Seva, A. d. P.; Romano, A. P. M.; Franco, A. C.; Ribeiro, B. M.; Roehe, P. M.; Almeida, M. A. B. d.

10.1101/2021.07.16.452727 — genomics — Posted on 2021-07-19

1639 Low-coverage sequencing in a deep intercross of the Virginia body weight lines provides insight to the polygenic genetic architecture of growth: novel loci revealed by increased power and improved genome-coverage

Rönneburg, T.; Zan, Y.; Honaker, C. F.; Siegel, P. B.; Carlborg, O.

10.1101/2021.07.19.451141 — genetics — Posted on 2021-07-19

1640 The effect of periodic disturbances and carrying capacity on the significance of selection and drift in complex bacterial communities

Gundersen, M. S.; Morelan, I.; Andersen, T.; Bakke, I.; Vadstein, O.

10.1101/2021.07.18.452870 — ecology — Posted on 2021-07-19

1641 Integrative multi-omics landscape of non-structural protein 3 of severe acute respiratory syndrome coronaviruses

Shi, R.; Feng, Z.; Zhang, X.

10.1101/2021.07.19.452910 — cell biology — Posted on 2021-07-19

1642 A nationwide genomic study of clinical Klebsiella pneumoniae in Norway 2001-2015: Introduction and spread of ESBL facilitated by CG15 and CG307

Fostervold, A.; Hetland, M. A. K.; Bakksjo, R.-J.; Bernhoff, E.; Holt, K.; Samuelsen, O.; Simonsen, G. S.; Sundsfjord, A.; Wyres, K. L.; Lohr, I. H.; The Norwegian Study Group on Klebsiella pneumoniae,

10.1101/2021.07.16.452602 — microbiology — Posted on 2021-07-19

1643 Susceptibilities of human ACE2 genetic variants in coronavirus infection

Ren, W.; Zhu, Y.; Lan, J.; Chen, H.; Wang, Y.; Shi, H.; Feng, F.; Chen, D.-Y.; Close, B.; Zhao, X.; Wu, J.; Tian, B.; Yuan, Z.; Zhou, D.; Saeed, M.; Wang, X.; Zhang, R.; Ding, Q.

10.1101/2021.07.18.452826 — microbiology — Posted on 2021-07-19

1644 SARS-CoV-2 Spike Pseudoviruses: A Useful tool to study virus entry and address emerging neutralization escape phenotypes

Kalkeri, R.; Cai, Z.; Lin, S.; Farmer, J.; Kuzmichev, Y. V.; Koide, F.

10.1101/2021.07.16.452709 — microbiology — Posted on 2021-07-19

1645 One mucosal administration of a live attenuated recombinant COVID-19 vaccine protects non-human primates from SARS-CoV-2

Tioni, M. F.; Jordan, R.; Silva Pena, A.; Garg, A.; Wu, D.; Phan, S. I.; Cheng, X.; Greenhouse, J.; Orekov, T.; Valentin, D.; Kar, S.; Pessaint, L.; Andersen, H.; Stobart, C. C.; Bloodworth, M. H.; Peebles, R. S.; Liu, Y.; Xie, X.; Shi, P.-Y.; Moore, M. L.; Tang, R. S.

10.1101/2021.07.16.452733 — immunology — Posted on 2021-07-19

1646 A mosaic adeno-associated virus vector as a versatile tool that exhibits high levels of transgene expression and neuron specificity in primate brain

Kimura, K.; Nagai, Y.; Hatanaka, G.; Fang, Y.; Zheng, A.; Fujiwara, M.; Nakano, M.; Hori, Y.; Takeuchi, R.; Inagaki, M.; Minamimoto, T.; Fujita, I.; Inoue, K.-i.; Takada, M.

10.1101/2021.07.18.452859 — neuroscience — Posted on 2021-07-19

1647 Botrytis cinerea BcPTP1 is a late infection phase, cysteine rich protein cytotoxic effector

Zhu, W.; Yu, M.; Xu, R.; Bi, K.; Xiong, C.; Liu, Z.; Sharon, A.; Jiang, D.; Wu, M.; Gu, Q.; Gong, L.; Chen, W.; Wei, W.

10.1101/2021.07.18.452873 — pathology — Posted on 2021-07-19

1648 Phenotypic plasticity and genetic control in colorectal cancer evolution

Househam, J.; Heide, T.; Cresswell, G. D.; Lynn, C.; Spiteri, I.; Mossner, M.; Kimberley, C.; Gabbutt, C.; Lakatos, E.; Berner, A.; Schmidt, M.; Baker, A.-M.; Fernandez-Mateos, J.; Chen, B.; Zapata, L.; James, C.; Nichol, D.; Costa, H.; Mitchinson, M.; Jansen, M.; Caravagna, G.; Shibata, D.; Bridgewater, J.; Rodriguez-Justo, M.; Magnani, L.; Sottoriva, A.; Graham, T. A.

10.1101/2021.07.18.451272 — cancer biology — Posted on 2021-07-19

1649 ARF4-mediated Retrograde Trafficking Drives Chemoresistance in Glioblastoma

Budhiraja, S.; Baisiwala, S.; Perrault, E.; Cho, S.; Nandoliya, K.; Dara, G.; Zolp, A.; Chen, L.; Dmello, C.; Park, C.; Sonabend, A.; Ahmed, A.

10.1101/2021.07.18.451328 — cancer biology — Posted on 2021-07-19

1650 Mutation-induced Changes in the Receptor-binding Interface of the SARS-CoV-2 Delta Variant B.1.617.2 and Implications for Immune Evasion

Baral, P.; Bhattarai, N.; Hossen, M. L.; Stebliankin, V.; Gerstman, B.; Narasimhan, G.; Chapagain, P. P.

10.1101/2021.07.17.452576 — biophysics — Posted on 2021-07-19

1651 The genomic formation of Tanka people, an isolated 'Gypsies in water' in the coastal region of Southeast China

He, G. G.; Zhang, Y.; Wei, L.-H.; Wang, M.; Yang, X.; Guo, J.; Hu, R.; Wang, C.-C.; Zhang, X.-Q.

10.1101/2021.07.18.452867 — genetics — Posted on 2021-07-19

1652 Huntington's disease age at motor onset is modified by the tandem hexamer repeat in TCERG1

Lobanov, S. V.; McAllister, B.; McDade-Kumar, M.; Landwehrmeyer, G. B.; Rosser, A. E.; REGISTRY Investigators of the European Huntington's disease network, ; Paulsen, J. S.; PREDICT-HD Investigators of the Huntington Study Group, ; Lee, J.-M.; MacDonald, M. E.; Gusella, J.; Ryten, M.; Williams, N.; Holmans, P.; Massey, T. H.; Jones, L.

10.1101/2021.07.16.452643 — genetics — Posted on 2021-07-19

1653 Molecular evolution and structural analyses of the spike glycoprotein from Brazilian SARS-CoV-2 genomes: the impact of the fixation of selected mutations

Ferrareze, P. A. G.; Zimerman, R.; Franceschi, V. B.; Caldana, G. D.; Netz, P.; Thompson, C. E.

10.1101/2021.07.16.452571 — evolutionary biology — Posted on 2021-07-19

1654 ACE2 binding is an ancestral and evolvable trait of sarbecoviruses

Starr, T. N.; Zepeda, S. K.; Walls, A. C.; Greaney, A. J.; Veesler, D.; Bloom, J. D.

10.1101/2021.07.17.452804 — evolutionary biology — Posted on 2021-07-19

1655 Severe introduced predator impacts despite attempted functional eradication

Cheng, B. S.; Blumenthal, J.; Chang, A. L.; Barley, J.; Ferner, M. C.; Nielsen, K. J.; Ruiz, G. M.; Zabin, C. J.

10.1101/2021.07.19.451788 — ecology — Posted on 2021-07-19

1656 Identification and characterization of hPSC-derived FOXA2+ progenitor cells with ventricular cardiac differentiation potential

Dubois, N.; Calderon, D.; Wickramasinghe, N.; Sarrafha, L.; Schaniel, C.; Chen, S.; Tomishima, M.

10.1101/2021.07.18.452860 — developmental biology — Posted on 2021-07-19

1657 Parkinson' disease medication alters rat small intestinal motility and microbiota composition

van Kessel, S. P.; Bullock, A.; van Dijk, G.; El Aidy, S.

10.1101/2021.07.19.452878 — microbiology — Posted on 2021-07-19

1658 Rhodanese Rdl2 produces reactive sulfur species to scavenge hydroxyl radical and protect mitochondria

Wang, Q.; Chen, Z.; Zhang, X.; Xin, Y.; Xia, Y.; Xun, L.; Liu, H.

10.1101/2021.07.19.452856 — microbiology — Posted on 2021-07-19

1659 Vaccinia Virus Arrests and Shifts the Cell Cycle

Martin, C. K.; Samolej, J.; Olson, A. T.; Bertoli, C.; Wiebe, M. S.; de Bruin, R. A. M.; Mercer, J.

10.1101/2021.07.19.452625 — microbiology — Posted on 2021-07-19

1660 SARS-CoV-2 spike P681R mutation, a hallmark of the Delta variant, enhances viral fusogenicity and pathogenicity

Saito, A.; Irie, T.; Suzuki, R.; Maemura, T.; Nasser, H.; Uriu, K.; Kosugi, Y.; Shirakawa, K.; Sadamasu, K.; Kimura, I.; Ito, J.; Wu, J.; Iwatsuki-Horimoto, K.; Ito, M.; Yamayoshi, S.; Ozono, S.; Butlertanaka, E. P.; Tanaka, Y. L.; Shimizu, R.; Shimizu, K.; Yoshimatsu, K.; Kawabata, R.; Sakaguchi, T.; Tokunaga, K.; Yoshida, I.; Asakura, H.; Nagashima, M.; Kazuma, Y.; Nomura, R.; Horisawa, Y.; Yoshimura, K.; Takaori-Kondo, A.; Imai, M.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Nakagawa, S.; Ikeda, T.; Fukuhara, T.; Kawaoka, Y.; Sato, K.

10.1101/2021.06.17.448820 — microbiology — Posted on 2021-07-19

1661 Improving human coronavirus OC43 (HCoV-OC43) research results comparability in studies using HCoV-OC43 as a surrogate for SARS-CoV-2

Schirtzinger, E. E.; Kim, Y.; Davis, A. S.

10.1101/2021.07.14.452401 — microbiology — Posted on 2021-07-19

1662 Macrophages govern antiviral responses in human lung tissues protected from SARS-CoV-2 infection

Kenney, D. J.; O'Connell, A. K.; Turcinovic, J.; Montanaro, P.; Hekman, R. M.; Tamura, T.; Berneshawi, A. R.; Cafiero, T. R.; Al Abdullatif, S.; Blum, B.; Goldstein, S. I.; Heller, B.; Gertje, H. P.; Bullitt, E.; Trachtenberg, A. J.; Chavez, E.; Sheikh, A.; Kurnick, S.; Grosz, K.; Bosmann, M.; Ericsson, M.; Huber, B. R.; Saeed, M.; Balazs, A. B.; Francis, K. P.; Klose, A.; Paragas, N.; Campbell, J. D.; Connor, J. H.; Emili, A.; Crossland, N. A.; Ploss, A.; Douam, F.

10.1101/2021.07.17.452554 — microbiology — Posted on 2021-07-19

1663 The critical role of spiny stellate cells in seizure onset based on dynamic analysis of a neural mass model

Tabatabaee, S.; Bahrami, F.; Janahmadi, M.

10.1101/2021.07.19.452876 — neuroscience — Posted on 2021-07-19

1664 Ensemble encoding of conditioned fear by prefrontal somatostatin interneurons

Cummings, K. A.; Bayshtok, S.; Kenny, P. J.; Clem, R. L.

10.1101/2021.07.18.452791 — neuroscience — Posted on 2021-07-19

1665 A unified framework for measuring selection on cellular lineages and traits

Yamauchi, S.; Nozoe, T.; Okura, R.; Kussell, E.; Wakamoto, Y.

10.1101/2021.07.18.452747 — systems biology — Posted on 2021-07-19

1666 Auxin and pectin remodeling interplay during rootlet emergence in white lupin

Jobert, F.; Soriano, A.; Brottier, L.; Casset, C.; Divol, F.; Safran, J.; LEFEBVRE, V.; PELLOUX, J.; Robert, S.; PERET, B.

10.1101/2021.07.19.452882 — plant biology — Posted on 2021-07-19

1667 gmxapi: a Gromacs-native Python interface for molecular dynamics with ensemble and plugin support

Irrgang, M. E.; Davis, C.; Kasson, P.

10.1101/2021.07.18.452496 — bioinformatics — Posted on 2021-07-19

1668 Fast and efficient CRISPR-mediated genome editing in Aureobasidium pullulans using Cas9 ribonucleoproteins

Kreuter, J.; Stark, G.; Mach, R. L.; Mach-Aigner, A. R.; Derntl, C.

10.1101/2021.07.19.452881 — bioengineering — Posted on 2021-07-19

1669 ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1

Aykul, S.; Huang, L.; Wang, L.; Das, N.; Reisman, S.; Ray, Y.; Zhang, Q.; Rothman, N.; Nannuru, K. C.; Kamat, V.; Brydges, S.; Troncone, L.; Johnsen, L.; Yu, P. B.; Lees-Shepard, J.; Schutz, K.; Murphy, A. J.; Economides, A. N.; Idone, V.; Hatsell, S. J.

10.1101/2021.07.18.452865 — biochemistry — Posted on 2021-07-19

1670 Single cell analysis reveals X chromosome upregulation is not global and primarily belongs to ancestral genes in pre-gastrulation embryos

Naik, H.; Chandel, D.; Gayen, S.

10.1101/2021.07.18.452817 — genetics — Posted on 2021-07-19

1671 Empirical prediction of variant-associated cryptic-donors with 87% sensitivity and 95% specificity

Dawes, R.; Joshi, H.; Cooper, S. T.

10.1101/2021.07.18.452855 — genetics — Posted on 2021-07-19

1672 Evolution of Plant Niche Construction Traits in Biogeomorphic Landscapes

Dong, X.

10.1101/2021.07.18.452868 — evolutionary biology — Posted on 2021-07-19

1673 Facultative variation across a shallow to deep torpor spectrum in hummingbirds

Shankar, A.; Cisneros, I. N.; Thompson, S.; Graham, C. H.; Powers, D. R.

10.1101/2021.07.18.452827 — ecology — Posted on 2021-07-19

1674 A cannabinoid receptor agonist shows anti-inflammatory and survival properties in human SARS-CoV-2-infected iPSC-derived cardiomyocytes

Aragao, L. G. H. S.; Oliveira, J. T.; Temerozo, J. R.; Mendes, M. A.; Salerno, J. A.; Pedrosa, C. d. S. G.; Puig-Pijuan, T.; Verissimo, C.; Ornelas, I. M.; Torquato, T.; Vitoria, G.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Dias, S. d. S. G.; Cardoso Soares, V.; Souza, L. R. Q.; Karmirian, K.; Goto-Silva, L.; Biagi, D.; Cruvinel, E. M.; Dariolli, R.; Furtado, D. R.; Bozza, P. T.; Borges, H. L.; Souza, T. M. L.; Guimaraes, M. Z. P.; Rehen, S.

10.1101/2021.02.20.431855 — cell biology — Posted on 2021-07-19

1675 CLARA: A web portal for interactive exploration of the cardiovascular cellular landscape in health and disease

Dona, M. S. I.; Hsu, I.; Rathnayake, T. S.; Farrugia, G. E.; Gaynor, T. L.; Kharbanda, M.; Skelly, D. A.; Pinto, A. R.

10.1101/2021.07.18.452862 — cell biology — Posted on 2021-07-19

1676 Senescence of stromal cells contributes to endometrium dysfunction and embryo implantation failure

Deryabin, P. I.; Ivanova, J. S.; Borodkina, A. V.

10.1101/2021.07.19.452880 — cell biology — Posted on 2021-07-19

1677 Altered cortical processing of sensory input in Huntington disease mouse models

Sepers, M. D.; Mackay, J. P.; Koch, E.; Xiao, D.; Mohajerani, M. H.; Chan, A. W.; Smith-Dijak, A. I.; Ramandi, D.; Murphy, T. H.; Raymond, L. A.

10.1101/2021.07.18.452688 — neuroscience — Posted on 2021-07-19

1678 EEG Biomarkers of reduced inhibition in human cortical microcircuits in depression

Mazza, F.; Griffiths, J. D.; Hay, E.

10.1101/2021.07.18.452836 — neuroscience — Posted on 2021-07-19

1679 FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons

Hale, C. R.; Sawicka, K.; Mora, K.; Fak, J. J.; Kang, J. J.; Cutrim, P.; Cialowicz, K.; Carroll, T.; B. Darnell, R.

10.1101/2021.07.18.452839 — neuroscience — Posted on 2021-07-19

1680 Common molecular mechanisms underlie the transfer of alpha-synuclein, Tau and huntingtin and modulate spontaneous activity in neuronal cells

Bras, I. C.; Khani, M. H.; Vasili, E.; Mobius, W.; Riedel, D.; Parfentev, I.; Gerhardt, E.; Fahlbusch, C.; Urlaub, H.; Zweckstetter, M.; Gollisch, T.; Outeiro, T. F.

10.1101/2021.07.18.452825 — neuroscience — Posted on 2021-07-19

1681 Pleiotropic Variability Score: A Genome Interpretation Metric to Quantify Phenomic Associations of Genomic Variants

Khader, S.; Glicksberg, B.; Johnson, K. W.; Badgeley, M.; Dudley, J.

10.1101/2021.07.18.452819 — bioinformatics — Posted on 2021-07-19

1682 Prior Signal Acquisition Software Versions for Orbitrap Underestimate Low Isobaric Mass Tag Intensities, Without Detriment to Differential Abundance Experiments

Smith, T. S.; Andrejeva, A.; Christopher, J. A.; Crook, O. M.; Elzek, M. A. W.; Lilley, K. S.

10.1101/2021.07.18.452841 — bioinformatics — Posted on 2021-07-19

1683 CoLoRd: Compressing long reads

Kokot, M.; Gudys, A.; Li, H.; Deorowicz, S.

10.1101/2021.07.17.452767 — bioinformatics — Posted on 2021-07-19

1684 Application of personalized differential expression analysis in human cancer proteome

yachen, l.; yalan, l.; yujuan, w.; zheyang, z.; mengsha, t.; rongshan, y.

10.1101/2021.07.18.452812 — bioinformatics — Posted on 2021-07-19

1685 Docking Molecular analysis of potential Aldosterone antagonists

FERRARI, I. V.; Patrizio, P.

10.1101/2021.07.18.452814 — bioinformatics — Posted on 2021-07-19

1686 PLIGHT: A tool to assess privacy risk by inferring identifying characteristics from sparse, noisy genotypes

Emani, P. S.; Gursoy, G.; Miranker, A. D.; Gerstein, M.

10.1101/2021.07.18.452853 — bioinformatics — Posted on 2021-07-19

1687 Structural Characterization of the PawL-Derived Peptide Family, an Ancient Subfamily of Orbitides

Payne, C. D.; Fisher, M. F.; Mylne, J. S.; Rosengren, K. J.

10.1101/2021.07.18.452857 — biochemistry — Posted on 2021-07-19

1688 Dosage compensation in Bombyx mori is achieved by partial repression of both Z chromosomes in males

Rosin, L. F.; Chen, Y.; Lei, E. P.

10.1101/2021.07.18.452821 — genetics — Posted on 2021-07-19

1689 Isotropic Reconstruction of Electron Tomograms with Deep Learning

Liu, Y.-T.; Zhang, H.; Wang, H.; Tao, C.-L.; Bi, G.-Q.; Zhou, Z. H.

10.1101/2021.07.17.452128 — cell biology — Posted on 2021-07-19

1690 Decoding molecular and cellular heterogeneity of nucleus accumbens with high-throughput scRNA-seq and MERFISH

Chen, R.; Blosser, T. R.; Djekidel, M. N.; Hao, J.; Bhattacherjee, A.; Chen, W.; Tuesta, L. M.; Zhuang, X.; Zhang, Y.

10.1101/2021.07.17.452808 — neuroscience — Posted on 2021-07-19

1691 Traces of semantization - from episodic to semantic memory in a spiking cortical network model

Chrysanthidis, N.; Fiebig, F.; Lansner, A.; Herman, P.

10.1101/2021.07.18.452769 — neuroscience — Posted on 2021-07-19

1692 Towards on-chip real-time classification of extra-cellular neural recordings

Ozdas, M.; Gronskaya, E.; von der Behrens, W.; Indiveri, G.

10.1101/2021.07.18.452831 — neuroscience — Posted on 2021-07-19

1693 Lane-maze for preference testing in flies

Eckert, F. B.; Valdati, D. d. B.; Marino-Neto, J.; de Toni, D. C.; Lino de Oliveira, C.

10.1101/2021.07.18.452790 — neuroscience — Posted on 2021-07-19

1694 Sex-Specific Computational Models of Kidney Function in Human Patients with Diabetes

Swapnasrita, S.; Carlier, A.; Layton, A.

10.1101/2021.07.17.452799 — physiology — Posted on 2021-07-19

1695 Open access in silico tools to predict the ADMET profiling and PASS (Prediction of Activity Spectra for Substances of Bioactive compounds of Garlic (Allium sativum L.)

Ferrari, I. V.

10.1101/2021.07.18.452815 — bioinformatics — Posted on 2021-07-19

1696 Causal inference using deep-learning variable selection identifies and incorporates direct and indirect causalities in complex biological systems

Fan, Z.; Kernan, K. F.; Benos, P. V.; Cooper, G. F.; Canna, S. W.; Carcillo, J. A.; Kim, S.; Park, H. J.

10.1101/2021.07.17.452800 — bioinformatics — Posted on 2021-07-19

1697 HAMdetector: A Bayesian regression model that integrates information to detect HLA-associated mutations

Habermann, D.; Karimzadeh, H.; Walker, A.; Li, Y.; Yang, R.; Brumme, Z. L.; Timm, J.; Roggendorf, M.; Hoffmann, D.

10.1101/2021.07.17.452375 — bioinformatics — Posted on 2021-07-19

1698 Experimental investigations of the human oesophagus: anisotropic properties of the muscular layer in large deformation

Durcan, C.; Hossain, M.; Chagnon, G.; Peric, D.; Bsiesy, L.; Karam, G.; Girard, E.

10.1101/2021.07.18.452813 — bioengineering — Posted on 2021-07-19

1699 Darwin's finches can have taste preferences, but not for human foods

Lever, D.; Rush, L. V.; Thorogood, R.; Gotanda, K. M.

10.1101/2021.07.17.452789 — animal behavior and cognition — Posted on 2021-07-19

1700 Discovering cellular programs of intrinsic and extrinsic drivers of metabolic traits using LipocyteProfiler

Strobel, S.; Laber, S.; Mercader, J. M.; Dashti, H.; Ainbinder, A.; Honecker, J.; Garborcauskas, G.; Stirling, D. R.; Leong, A.; Figueroa, K.; Sinnott-Armstrong, N.; Kost-Alimova, M.; Deodato, G.; Harney, A.; Way, G. P.; Saadat, A.; Harken, S.; Reibe-Pal, S.; Ebert, H.; Zhang, Y.; Calabuig, V.; McGonagle, E.; Stefek, A.; Dupuis, J.; Cimini, B.; Hauner, H.; Udler, M. S.; Carpenter, A. E.; Florez, J. C.; Lindgren, C. M.; Jacobs, S. B.; Claussnitzer, M.

10.1101/2021.07.17.452050 — genomics — Posted on 2021-07-19

1701 Gene regulation is commonly selected for high plasticity and low noise

Vlkova, M.; Silander, O. K.

10.1101/2021.07.18.452581 — evolutionary biology — Posted on 2021-07-19

1702 Genetically-based adaptive trait shifts at an expanding mangrove range margin

Kennedy, J. P.; Johnson, G. N.; Preziosi, R. F.; Rowntree, J. K.

10.1101/2021.07.17.452777 — ecology — Posted on 2021-07-19

1703 Coarse-graining ecological dynamics in the face of unknown microscopic details

Moran, J.; TIKHONOV, M.

10.1101/2021.07.17.452786 — ecology — Posted on 2021-07-19

1704 The age and mouse sperm quality: a flow cytometry investigation

Zacchini, F.; Bochenek, M.; Bisogno, S.; Chan, A.; Ptak, G. E.

10.1101/2021.07.18.451583 — developmental biology — Posted on 2021-07-19

1705 Echidna: integrated simulations of single-cell immune receptor repertoires and transcriptomes

Han, J.; Kuhn, R.; Papadopoulou, C.; Agrafiotis, A.; Kreiner, V.; Shlesinger, D.; Dizerens, R.; Hong, K.-L.; Weber, C.; Greiff, V.; Oxenius, A.; Reddy, S. T.; Yermanos, A.

10.1101/2021.07.17.452792 — immunology — Posted on 2021-07-19

1706 Axial spondyloarthritis patients have altered mucosal IgA response to oral and fecal microbiota

Gill, T.; Stauffer, P.; Asquith, M.; Laderas, T.; Martin, T. M.; Davin, S.; Schleisman, M.; Ramirez, C.; Ogle, K.; Lindquist, I.; Nguyen, J.; Planck, S. R.; Shaut, C.; Diamond, S.; Rosenbaum, J. T.; Karstens, L.

10.1101/2021.07.15.452558 — immunology — Posted on 2021-07-19

1707 Pre-trauma memory contextualization as predictor for PTSD-like behavior in male rats

Sep, M. S. C.; Sarabdjitsingh, R. A.; Geuze, E.; Joels, M.

10.1101/2021.07.17.452780 — neuroscience — Posted on 2021-07-19

1708 Online tests yield robust thresholds with the right auditory hygiene

Zhao, S.; Brown, C. A.; Holt, L. L.; Dick, F.

10.1101/2021.07.17.452796 — neuroscience — Posted on 2021-07-19

1709 A Reinforcement Meta-Learning Framework of Executive Function and Information Demand

Silvetti, M.; Lasaponara, S.; Horan, M.; Gottlieb, J.

10.1101/2021.07.18.452793 — neuroscience — Posted on 2021-07-19

1710 The balance of mitochondrial fission and fusion in cortical axons depends on the kinases SadA and SadB

Di Meo, D.; Ravindran, P.; Dhumale, P.; Puschel, A. W.

10.1101/2021.07.18.452621 — neuroscience — Posted on 2021-07-19

1711 Selenium in wheat from farming to food

Wang, M.; Li, B.; Li, S.; Kong, F.; Zhang, X.

10.1101/2021.07.17.452805 — plant biology — Posted on 2021-07-19

1712 Assessing the polymer coil-globule state from the very first spectral modes

Földes, T.; Lesage, A.; Barbi, M.

10.1101/2021.07.17.452647 — biophysics — Posted on 2021-07-19

1713 Modelling, characterization of data-dependent and process-dependent errors in DNA data storage

Yixin, W.; Rahim, M. N.; Gunawan, E.; Guan, Y. L.; Poh, C. L.

10.1101/2021.07.17.452779 — bioinformatics — Posted on 2021-07-19

1714 Machine-learning-based predictions of caloricrestriction associations across ageing-related genes

Vega-Magdaleno, G. D.; Bespalov, V.; Zheng, Y.; Freitas, A.; de Magalhaes, J. P.

10.1101/2021.07.17.452785 — bioinformatics — Posted on 2021-07-19

1715 A Sequence-based Antibody Paratope Prediction Model Through Combing Local-Global Information and Partner Features

Lu, S.; Li, Y.; Nan, X.; Zhang, S.

10.1101/2021.07.17.452531 — bioinformatics — Posted on 2021-07-19

1716 SprayNPray: user-friendly taxonomic profiling of genome and metagenome contigs

Garber, A. I.; Armbruster, C. R.; Lee, S. E.; Cooper, V. S.; Bomberger, J. M.; McAllister, S. M.

10.1101/2021.07.17.452725 — bioinformatics — Posted on 2021-07-19

1717 A comparative in vitro and in vivo study of osteogenicity by using two biomaterials and two human mesenchymal stem cell subtypes

Fievet, L.; Serratrice, N.; Brulin, B.; Giraudo, L.; Veran, J.; Sabatier, F.; Degardin, N.; Feron, F.; Layrolle, P.

10.1101/2021.07.17.452782 — bioengineering — Posted on 2021-07-19

1718 The role of cytosolic polyadenylation element binding protein 2 alternative splicing in hypoxia

Mayo, E. M.; Stevens, S. C.; Ali, A. N.; Moss, C. J.; Lund, S. P.; Nazario-Munoz, G. S.; Permuth, J. B.; Westerheide, S. D.; Chalfant, C. E.; Park, M. A.

10.1101/2020.10.05.325290 — cell biology — Posted on 2021-07-19

1719 Dynamic mechanisms of CRISPR interference by Escherichia coli CRISPR-Cas3

Yoshimi, K.; TAKESHITA, K.; Kodera, N.; Shibumura, S.; Yamauchi, Y.; Omatsu, M.; Kunihiro, Y.; Yamamoto, M.; Mashimo, T.

10.1101/2021.07.18.452824 — molecular biology — Posted on 2021-07-19

1720 Interferon-Induced Transmembrane Proteins Inhibit Infection by the Kaposis Sarcoma-Associated Herpesvirus and the Related Rhesus Monkey Rhadinovirus in a Cell Type-Specific Manner.

Hörnich, B. F.; Grosskopf, A. K.; DCosta, C. J.; Schlagowski, S.; Hahn, A. S.

10.1101/2021.07.16.452764 — microbiology — Posted on 2021-07-19

1721 Identification of Key Pathways and Genes in Dementia via Integrated Bioinformatics Analysis

Vastrad, B. M.; Vastrad, C. M.

10.1101/2021.04.18.440371 — bioinformatics — Posted on 2021-07-19

1722 Structural dynamics and catalytic mechanism of ATP13A2 (PARK9) from simulations

Mateeva, T.; Klaehn, M.; Rosta, E.

10.1101/2021.06.01.446648 — biophysics — Posted on 2021-07-19

1723 Enhancing the prediction of protein coding regions in biological sequence via a deep learningframework with hybrid encoding

Wei, C.; Zhang, J.; Yuan, X.

10.1101/2020.11.07.372524 — bioinformatics — Posted on 2021-07-19

1724 Evolutionary coupling range varies widely among enzymes depending on selection pressure

Echave, J.

10.1101/2020.12.19.423588 — evolutionary biology — Posted on 2021-07-19

1725 A meta-analysis of the effect of organic and mineral fertilizers on soil microbial diversity

Bebber, D. P.; Richards, V. R.

10.1101/2020.10.04.325373 — ecology — Posted on 2021-07-19

1726 Using diffusion MRI data acquired with ultra-high gradients to improve tractography in routine-quality data

Maffei, C.; Lee, C.; Planich, M.; Ramprasad, M.; Ravi, N.; Trainor, D.; Urban, Z.; Kim, M.; Jones, R.; Henin, A.; Hofmann, S.; Pizzagalli, D.; Auerbach, R.; Gabrieli, J.; Whitfield-Gabrieli, S.; Greve, D.; Haber, S.; Yendiki, A.

10.1101/2021.06.28.450265 — neuroscience — Posted on 2021-07-19

1727 Genetic mapping of sex and self-incompatibility determinants in the androdioecious plant Phillyrea angustifolia

Carre, A.; Gallina, S.; Santoni, S.; Vernet, P.; Gode, C.; Castric, V.; Saumitou-Laprade, P.

10.1101/2021.04.15.439943 — evolutionary biology — Posted on 2021-07-19

1728 Cortical spheroids display oscillatory network dynamics

Sevetson, J. L.; Theyel, B.; Hoffman-Kim, D.

10.1101/2021.07.18.452530 — neuroscience — Posted on 2021-07-18

1729 In vivo visualization of propagating α-synuclein pathologies in mouse and marmoset models by a bimodal imaging probe, C05-05

Ono, M.; Takahashi, M.; Shimozawa, A.; Fujinaga, M.; Mori, W.; Nagai, Y.; Mimura, K.; Kumata, K.; Kikuchi, T.; Shimojo, M.; Takuwa, H.; Minamihisamatsu, T.; Uchida, S.; Mishra, S. K.; Yamaguchi, Y.; Shimizu, H.; Kakita, A.; Endo, H.; Takado, Y.; Minamimoto, T.; Sahara, N.; Zhang, M.-R.; Hasegawa, M.; Higuchi, M.

10.1101/2020.10.23.349860 — neuroscience — Posted on 2021-07-19

1730 Your head is there to move you around: Goal-driven models of the primate dorsal pathway

Mineault, P. J.; Bakhtiari, S.; Richards, B. A.; Pack, C. C.

10.1101/2021.07.09.451701 — neuroscience — Posted on 2021-07-19

1731 Revision of the genus Dichaetophora Duda (Diptera: Drosophilidae), part I: DNA bar-coding and molecular phylogenetic reconstruction

Katoh, T. K.; Chen, J.-M.; Yang, J.-H.; Zhang, G.; Wang, L.; Suwito, A.; Toda, M. J.; Zhang, Y.-P.; Gao, J.-J.

10.1101/2021.05.28.446102 — zoology — Posted on 2021-07-19

1732 Graph Signal Processing on protein residue networks helps in studying its biophysical properties

Srivastava, D.; Bagler, G.; Kumar, V.

10.1101/2021.01.02.425090 — biophysics — Posted on 2021-07-19

1733 Regional cytoarchitecture of the adult and developing mouse enteric nervous system

Hamnett, R.; Dershowitz, L. B.; Sampathkumar, V.; Wang, Z.; De Andrade, V.; Kasthuri, N.; Druckmann, S.; Kaltschmidt, J. A.

10.1101/2021.07.16.452735 — neuroscience — Posted on 2021-07-18

1734 3D molecular phenotyping of cleared human brain tissues with light-sheet fluorescence microscopy

Pesce, L.; Scardigli, M.; Gavryusev, V.; Laurino, A.; Mazzamuto, G.; Sancataldo, G.; Silvestri, L.; Destrieux, C.; R. Hof, P.; Costantini, I.; Pavone, F.

10.1101/2021.07.18.452829 — neuroscience — Posted on 2021-07-18

1735 Spatio-temporal dynamics of stress-induced network reconfigurations reflect negative affectivity

Kuehnel, A.; Czisch, M.; Saemann, P. G.; BeCome Study Team, ; Binder, E. B.; Kroemer, N. B.

10.1101/2021.07.16.452622 — neuroscience — Posted on 2021-07-18

1736 Probing the toxic interactions between the reactive dye Drimaren Red and Human Serum Albumin

Menezes, T. M.; de Assis, C. R. D.; da Silva Neto, A. M.; Gubert, P.; Ghislandi, M. G.; Neves, J. L.

10.1101/2021.07.17.452798 — biophysics — Posted on 2021-07-18

1737 Finding Overlapping Rmaps via Gaussian Mixture Model Clustering

Mukherjee, K.; Rossi, M.; Dole-Muinos, D.; Ajayi, A.; Prosperi, M.; Boucher, C.

10.1101/2021.07.16.452722 — bioinformatics — Posted on 2021-07-18

1738 Merfin: improved variant filtering and polishing via k-mer validation

Formenti, G.; Rhie, A.; Walenz, B. P.; Thibaud-Nissen, F.; Shafin, K.; Koren, S.; Myers, E. W.; Jarvis, E. D.; Phillippy, A. M.

10.1101/2021.07.16.452324 — bioinformatics — Posted on 2021-07-18

1739 Ankyrin2 is required for neuronal morphogenesis and long-term memory and interacts genetically with HDAC4

Schwartz, S.; Wilson, S. J.; Hale, T. K.; Fitzsimons, H. L.

10.1101/2021.07.18.452850 — genetics — Posted on 2021-07-18

1740 Phosphorus availability and arbuscular mycorrhizal fungi limit soil C cycling and influence plant responses to elevated CO2 conditions.

Castaneda-Gomez, L.; Powell, J.; Pendall, E.; Carrillo, Y.

10.1101/2021.07.16.452715 — ecology — Posted on 2021-07-18

1741 Body size mediates latitudinal population differences in response to Bd infection in two amphibian species.

Meurling, S.; Cortazar-Chinarro, M.; Siljestam, M.; Ahlen, D.; Agren, E.; Hoglund, J.; Laurila, A.

10.1101/2021.07.16.452656 — ecology — Posted on 2021-07-18

1742 Multiple stage hydra effect in a stage-structured prey-predator model

Costa, M. I.; dos Anjos, L.; Esteves, P. V.

10.1101/2021.07.16.452738 — ecology — Posted on 2021-07-18

1743 TAF4b transcription networks regulating early oocyte differentiation

Gura, M. A.; Relovska, S.; Abt, K. M.; Seymour, K. A.; Wu, T.; Kaya, H.; Turner, J.; Fazzio, T. G.; Freiman, R. N.

10.1101/2021.07.18.452838 — developmental biology — Posted on 2021-07-18

1744 A rapid F0 CRISPR screen in zebrafish to identify regulators of neuronal development in the enteric nervous system

Davidson, A. E.; Straquadine, N. R.; Cook, S. A.; Liu, C. G.; Ganz, J.

10.1101/2021.07.17.452230 — developmental biology — Posted on 2021-07-18

1745 LENG8 regulation of mRNA processing, is responsible for the control of mitochondrial activity

Zhao, Y.; Wang, X.; Li, N.; Liu, Y.; Sun, Z.; Wang, S.; Gao, Z.; Zhang, X.; Mao, L.; Tang, R.; Xue, W.; Li, C.; Guan, J.; Yi, H.; Zhang, N.; Ding, Q.; Liu, F.

10.1101/2021.07.17.452750 — cell biology — Posted on 2021-07-18

1746 Dynamic surveillance of mosquitoes and their viromes in Wuhan during 2020.

Ren, N.; Wang, S.; Shi, C.; Yu, P.; Zhao, L.; Huang, D.; Ma, H.; Xiao, S.; Wang, F.; Yuan, Z.; Xia, H.

10.1101/2021.07.17.452774 — microbiology — Posted on 2021-07-18

1747 APOE2, E3 and E4 differentially modulate cellular homeostasis, cholesterol metabolism and inflammatory response in isogenic iPSC-derived astrocytes

de Leeuw, S.; Kirschner, A. W.; Lindner, K.; Rust, R.; Wolski, W. E.; Gavin, A.-C.; Nitsch, R. M.; Tackenberg, C.

10.1101/2021.07.17.452644 — neuroscience — Posted on 2021-07-18

1748 Ipsilateral stimulus encoding in primary and secondary somatosensory cortex of awake mice

Pala, A.; Stanley, G. B.

10.1101/2021.07.16.452704 — neuroscience — Posted on 2021-07-18

1749 Chloride oscillation in pacemaker neurons regulates circadian rhythms through a chloride-sensing WNK kinase signaling cascade

Schellinger, J. N.; Sun, Q.; Pleinis, J. M.; An, S.-W.; Hu, J.; Mercenne, G.; Titos, I.; Huang, C.-L.; Rothenfluh, A.; Rodan, A. R.

10.1101/2021.07.16.452737 — neuroscience — Posted on 2021-07-18

1750 Radical pairs can explain magnetic field and lithium effects on the circadian clock

Zadeh-Haghighi, H.; Simon, C.

10.1101/2021.07.16.452701 — neuroscience — Posted on 2021-07-18

1751 Impact of acute visual experience on development of LGN receptive fields in the ferret

Stacy, A. K.; Schneider, N. A.; Gilman, N. K.; Van Hooser, S. D.

10.1101/2021.07.16.452697 — neuroscience — Posted on 2021-07-18

1752 Using a Quadruplet Codon to Expand the Genetic Code of an Animal

Xi, Z.; Davis, L.; Baxter, K.; Tynan, A.; Goutou, A.; Greiss, S.

10.1101/2021.07.17.452788 — synthetic biology — Posted on 2021-07-18

1753 Deep neural language modeling enables functional protein generation across families

Madani, A.; Krause, B.; Greene, E. R.; Subramanian, S.; Mohr, B. P.; Holton, J. M.; Olmos, J. L.; Xiong, C.; Sun, Z. Z.; Socher, R.; Fraser, J. S.; Naik, N.

10.1101/2021.07.18.452833 — synthetic biology — Posted on 2021-07-18

1754 The low and high postpubertal ethanol use: long-term effects on drinkers reproductive parameters and ethanol-naive offspring development

Fioravante, V. C.; Godoi, A. R.; Camargo, V. M. d. B.; Pinheiro, P. F. F.; Padovani, C. R.; Martinez, M.; Martinez, F. E.

10.1101/2021.07.16.452713 — pharmacology and toxicology — Posted on 2021-07-18

1755 Autofluorescence microscopy as a label-free tool for renal histology and glomerular segmentation

Patterson, N. H.; Neumann, E. K.; Sharman, K.; Allen, J. L.; Harris, R. C.; Fogo, A. B.; deCaestecker, M. P.; Caprioli, R. M.; Van de Plas, R.; Spraggins, J. M.

10.1101/2021.07.16.452703 — bioinformatics — Posted on 2021-07-18

1756 Specificity of Loxosceles α clade phospholipase D enzymes for choline-containing lipids: role of a conserved aromatic cage

Moutoussamy, E. E.; Waheed, Q.; Binford, G. J.; Khan, H. M.; Moran, S. M.; Eitel, A. R.; Cordes, M. H. J.; Reuter, N.

10.1101/2021.07.16.452673 — bioinformatics — Posted on 2021-07-18

1757 Amplification-free detection of viral RNA by super resolution imaging-based CRISPR/Cas13a System

Qin, P.; Yu, D.; He, Q.; Chen, Q.; Li, F.; Yuan, X.; Liu, C.; Deng, L.; Zhang, Y. b.; Du, K.; Dong, Y.; Pandey, V.; Xu, L.; Zhong, X.; Wei, J.

10.1101/2021.07.17.452803 — bioengineering — Posted on 2021-07-18

1758 Genome-Wide Detection of Imprinted Differentially Methylated Regions Using Nanopore Sequencing

Akbari, V.; Garant, J.-M.; O'Neill, K.; Pandoh, P.; Moore, R.; Marra, M. A.; Hirst, M.; Jones, S. J.

10.1101/2021.07.17.452734 — genomics — Posted on 2021-07-18

1759 Genome size evolution in the diverse insect order Trichoptera

Heckenhauer, J.; Frandsen, P. B.; Sproul, J. S.; Li, Z.; Paule, J.; Larracuente, A. M.; Maughan, P. J.; Barker, M. S.; Schneider, J. V.; Stewart, R. J.; Pauls, S. U.

10.1101/2021.05.10.443368 — evolutionary biology — Posted on 2021-07-18

1760 Primary cilia drive postnatal tidemark patterning in articular cartilage by coordinating responses to Indian Hedgehog and mechanical load

Rux, D.; Helbig, K.; Han, B.; Cortese, C.; Koyama, E.; Han, L.; Pacifici, M.

10.1101/2021.07.04.451018 — developmental biology — Posted on 2021-07-18

1761 NDC1 is necessary for stable assembly of the nuclear pore scaffold to establish nuclear transport in early C. elegans embryos

Mauro, M. S.; Celma, G.; Zimyanin, V.; Gibson, K. H.; Redemann, S.; Bahmanyar, S.

10.1101/2021.07.17.452264 — cell biology — Posted on 2021-07-18

1762 Knockout of E-cadherin in adult mouse epithelium results in emphysema and airway disease

Ghosh, B.; Loube, J.; Thapa, S.; Capodanno, E.; Mahmud, S.; Girgis, M.; Chen, S.; Nishida, K.; Ying, L.; Swaby, C.; Wally, A.; Bhowmik, D. R.; Zaykaner, M. E.; Mitzner, W.; Sidhaye, V. K.

10.1101/2021.07.18.452342 — cell biology — Posted on 2021-07-18

1763 Sphingosine kinase 2 is essential for remyelination following cuprizone intoxication

Song, H.; McEwen, H. P.; Duncan, T.; Lee, J. Y.; Teo, J. D.; Don, A. S.

10.1101/2021.02.14.431183 — neuroscience — Posted on 2021-07-18

1764 Sensitivity to Error During Visuomotor Adaptation is Similarly Modulated by Abrupt, Gradual and Random Perturbation Schedules

Coltman, S.; van Beers, R. J.; Medendorp, P. W.; Gribble, P.

10.1101/2021.06.14.448375 — neuroscience — Posted on 2021-07-18

1765 Oct1 recruits the histone lysine demethylase Utx to canalize lineage specification

Perovanovic, J.; Wu, Y.; Shen, Z.; Hughes, E.; Chandrasekharan, M. B.; Tantin, D.

10.1101/2020.12.01.406488 — developmental biology — Posted on 2021-07-18

1766 Gene-Specific Nonsense-Mediated mRNA Decay Targeting for Cystic Fibrosis Therapy

Kim, Y. J.; Nomakuchi, T.; Papaleonidopoulou, F.; Krainer, A. R.

10.1101/2021.07.13.452144 — molecular biology — Posted on 2021-07-18

1767 Forward Entrainment: Evidence, Controversies, Constraints, and Mechanisms

Saberi, K.; Hickok, G.

10.1101/2021.07.06.451373 — neuroscience — Posted on 2021-07-18

1768 A hydro-osmotic coarsening theory of biological cavity formation

Le Verge-Serandour, M.; Turlier, H.

10.1101/2020.12.01.406991 — biophysics — Posted on 2021-07-18

1769 Defining the Sensitivity Landscape of 74,389 EGFR Variants to Tyrosine Kinase Inhibitors

An, L.; Chen, S.; Wu, G.; Liu, C.; Wang, Z.; Wang, C.; Shi, Z.; Niu, C.; Li, X.; Tang, W.; Xu, H.; Wang, Y.

10.1101/2021.07.18.452818 — genetics — Posted on 2021-07-18

1770 Co-variation between glucocorticoids, behaviour and immunity supports the pace-of-life syndrome hypothesis: an experimental approach

Carbillet, J.; Rey, B.; Palme, R.; Monestier, C.; Borger, L.; Lavabre, T.; Maublanc, M.-L.; Cebe, N.; Rames, J.-L.; Le Loc'h, G.; Wasniewski, M.; Rannou, B.; Gilot-Fromont, E.; Verheyden, H.

10.1101/2021.03.13.435238 — evolutionary biology — Posted on 2021-07-18

1771 Adult spiny mice (Acomys) exhibit endogenous cardiac recovery in response to myocardial infarction

Peng, H.; Shindo, K.; Donahue, R. R.; Gao, E.; Ahern, B. M.; Levitan, B. M.; Tripathi, H.; Powell, D.; Noor, A.; Satin, J.; Seifert, A. W.; Abdel-Latif, A.

10.1101/2020.09.29.317388 — developmental biology — Posted on 2021-07-18

1772 Longitudinal Auditory Pathophysiology Following Mild Blast Induced Trauma

Han, E. X.; Fernandez, J. M.; Swanberg, C.; Shi, R.; Bartlett, E. L.

10.1101/2020.11.06.371591 — neuroscience — Posted on 2021-07-18

1773 Simultaneous Brain, Brainstem and Spinal Cord pharmacological-fMRI reveals endogenous opioid network interactions mediating attentional analgesia

Oliva, V.; Hartley-Davies, R.; Moran, R. J.; Pickering, A. E.; Brooks, J.

10.1101/2021.05.05.442823 — neuroscience — Posted on 2021-07-18

1774 Local field potentials reflect cortical population dynamics in a region-specific and frequency-dependent manner

Gallego-Carracedo, C.; Perich, M. G.; Chowdhury, R. H.; Miller, L. E.; Gallego, J. A.

10.1101/2021.05.31.446454 — neuroscience — Posted on 2021-07-18

1775 Design considerations for workflow management systems use in production genomics research and the clinic

Ahmed, A. E.; Allen, J.; Bhat, T.; Burra, P.; Fliege, C. E.; Hart, S. N.; Heldenbrand, J. R.; Hudson, M. E.; Istanto, D. D.; Kalmbach, M. T.; Kapraun, G. D.; Kendig, K. I.; Kendzior, M. C.; Klee, E. W.; Mattson, N.; Ross, C. A.; Sharif, S. M.; Venkatakrishnan, R.; Fadlelmola, F. M.; Mainzer, L. S.

10.1101/2021.04.03.437906 — bioinformatics — Posted on 2021-07-18

1776 Study of Basic Local Alignment Search Tool (BLAST) and Multiple Sequence Alignment (Clustal- X) of Monoclonal mice/human antibodies

FERRARI, I. V.; PATRIZIO, P.

10.1101/2021.07.09.451785 — bioinformatics — Posted on 2021-07-18

1777 Dual effects of presynaptic membrane mimetics on α-synuclein amyloid aggregation

Lin, Y.; Ito, D.; Yoo, J. M.; Lim, M. H.; Yu, W. K.; Kawata, Y.; Lee, Y.-H.

10.1101/2021.07.13.452016 — biophysics — Posted on 2021-07-18

1778 The M1 and pre-M1 segments contribute differently to ion selectivity in ASICs and ENaCs

Sheikh, Z. P.; Wulf, M.; Friis, S.; Althaus, M.; Lynagh, T.; Pless, S. A.

10.1101/2021.02.16.431267 — biophysics — Posted on 2021-07-18

1779 The interplay of wind and uplift facilitates over-water flight in facultative soaring birds

Nourani, E.; Bohrer, G.; Becciu, P.; Bierregaard, R. O.; Duriez, O.; Figuerola, J.; Gangoso, L.; Giokas, S.; Higuchi, H.; Kassara, C.; Kulikova, O.; Lecomte, N.; Monti, F.; Pokrovsky, I.; Sforzi, A.; Therrien, J.-F.; Tsiopelas, N.; Vansteelant, W. M. G.; Viana, D. S.; Yamaguchi, N. M.; Wikelski, M.; Safi, K.

10.1101/2020.09.04.282939 — animal behavior and cognition — Posted on 2021-07-18

1780 Epithelial GPR35 protects from Citrobacter rodentium infection by preserving goblet cells and mucosal barrier integrity

Melhem, H.; Kaya, B.; Kaymak, T.; Wuggenig, P.; Flint, E.; Roux, J.; Cavelti-Weder, C.; Balmer, M.; Walser, J.-C.; Morales, R.; Riedel, C.; Liberali, P.; Villablanca, E.; Niess, J.

10.1101/2021.03.27.437264 — immunology — Posted on 2021-07-18

1781 Room Temperature Isothermal Colorimetric Padlock Probe Rolling Circle Amplification for Viral RNA Detection

Huang, W.; Ting, J.; Fang, M.; Hsu, H.; Su, J.; Misaki, T.; Chan, D.; Yang, J.; Yeh, T.-Y.; Yang, K.; Chien, V.; Huang, T.; Chen, A.; Wei, C.; Hsu, J.; Clapper, J. C.

10.1101/2020.06.12.128876 — synthetic biology — Posted on 2021-07-17

1782 Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops.

Urrutia, I.; Ault, J.; Sobott, F.; Savery, N.; Dillingham, M. S.

10.1101/2021.03.15.435481 — biochemistry — Posted on 2021-07-18

1783 REPINs are facultative genomic symbionts of bacterial genomes

Bertels, F.; Rainey, P. B.

10.1101/2021.07.10.451892 — evolutionary biology — Posted on 2021-07-17

1784 Novel Hendra virus variant detected by sentinel surveillance of Australian horses.

Annand, E. J.; Horsburgh, B. A.; Xu, K.; Reid, P. A.; Poole, B.; de Kantzow, M. C.; Brown, N.; Tweedie, A.; Michie, M.; Grewar, J. D.; Jackson, A. E.; Singanallur, N. B.; Plain, K. M.; Tachedjian, M.; van der Heide, B.; Williams, D. T.; Secombe, C.; Laing, E. D.; Sterling, S.; Yan, L.; Jackson, L.; Jones, C.; Plowright, R. K.; Peel, A. J.; Diallo, I.; Breed, A. C.; Broder, C. C.; Britton, P. N.; Dhand, N. K.; Smith, I.; Eden, J.-S.

10.1101/2021.07.16.452724 — molecular biology — Posted on 2021-07-18

1785 Pparα and fatty acid oxidation coordinate hepatic transcriptional architecture

Cavagnini, K. S.; Wolfgang, M. J.

10.1101/2021.07.12.451949 — molecular biology — Posted on 2021-07-18

1786 A strategy to suppress STAT1 signalling conserved in pathogenic poxviruses and paramyxoviruses

Talbot-Cooper, C.; Pantelejevs, T.; Shannon, J. P.; Cherry, C. R.; Au, M. T.; Hyvönen, M.; Hickman, H. D.; Smith, G. L.

10.1101/2021.07.17.452491 — microbiology — Posted on 2021-07-17

1787 An Ohio State Scenic River Shows Elevated Antibiotic Resistance Genes, Including Acinetobacter Tetracycline and Macrolide Resistance, Downstream of Wastewater Treatment Plant Effluent

Murphy, A. E.; Barich, D.; Fennessy, S.; Slonczewski, J. L.

10.1101/2021.04.26.441562 — microbiology — Posted on 2021-07-17

1788 Clonally expanded virus-specific CD8 T cells acquire diverse transcriptional phenotypes during acute, chronic, and latent infections

Kuhn, R.; Sandu, I.; Agrafiotis, A.; Hong, K.-L.; Neumeier, D.; Merkler, D.; Oxenius, A.; Reddy, S. T.; Yermanos, A.

10.1101/2021.06.29.450285 — immunology — Posted on 2021-07-17

1789 Degeneracy and stability in neural circuits of neuromodulators

Behera, C. K.; Joshi, A.; Wang, D.-H.; Sharp, T.; Wong-Lin, K.

10.1101/2020.09.25.313999 — neuroscience — Posted on 2021-07-17

1790 α-Synuclein facilitates clathrin assembly in synaptic vesicle endocytosis

Vargas, K. J.; Colosi, P. L.; Girardi, E.; Park, J.-M.; Chandra, S. S.

10.1101/2020.04.29.069344 — neuroscience — Posted on 2021-07-17

1791 Identification of phenotype-specific networks from paired gene expression-cell shape imaging data

Barker, C. G.; Petsalaki, E.; Giudice, G.; Sero, J.; Ekpenyong, E. N.; Bakal, C.; Petsalaki, E.

10.1101/2021.02.11.430597 — systems biology — Posted on 2021-07-17

1792 Identifying the Link Between Chemical Exposures and Breast Cancer in African American Women via ToxCast High Throughput Screening Data

Polemi, K.; Nguyen, V. K.; Heidt, J.; Kahana, A.; Jolliet, O.; Colacino, J.

10.1101/2021.01.22.427848 — pharmacology and toxicology — Posted on 2021-07-17

1793 CrowdGO: machine learning and semantic similarity guided consensus Gene Ontology annotation

Reijnders, M. J.; Waterhouse, R. M.

10.1101/731596 — bioinformatics — Posted on 2021-07-17

1794 A reference translatome map reveals two modes of protein evolution

Wacholder, A.; Acar, O.; Carvunis, A.-R.

10.1101/2021.07.17.452746 — genomics — Posted on 2021-07-17

1795 Interpreting Polygenic Score Effects in Sibling Analysis

Fletcher, J.; Wu, Y.; Li, T.; Lu, Q.

10.1101/2021.07.16.452740 — genetics — Posted on 2021-07-17

1796 Novel Hendra virus variant detected by sentinel surveillance of Australian horses.

10.1101/2021.07.16.452724 — molecular biology — Posted on 2021-07-17

1797 Increased microbial diversity and decreased prevalence of common pathogens in the gut microbiomes of wild turkeys compared to domestic turkeys

Craft, J.; Christman, N. D.; Eddington, H.; Chaston, J. M.; Erickson, D.; Wilson, E.

10.1101/2021.07.16.452759 — microbiology — Posted on 2021-07-17

1798 Proximity interactome analysis of Lassa polymerase reveals eRF3a/GSPT1 as a druggable target for host directed antivirals.

Fang, J.; Pietzsch, C.; Tsaprailis, G.; Crynen, G.; Cho, K. F.; Ting, A. Y.; Bukreyev, A.; Saphire, E. O.; de la Torre, J. C.

10.1101/2021.07.16.452739 — microbiology — Posted on 2021-07-17

1799 Identification of leptospiral protein antigens recognized by WC1+ γδ T cell subsets as target for development of recombinant vaccines

Teixeira, A.; Gillespie, A.; Yirsaw, A.; Britton, E.; Telfer, J.; do Nascimento, A. L.; Baldwin, C. L.

10.1101/2021.07.16.452762 — immunology — Posted on 2021-07-17

1800 Deep deconvolution of the hematopoietic stem cell regulatory microenvironment reveals a high degree of specialization and conservation between mouse and human.

Ye, J.; Calvo, I. A.; Cenzano, I.; Vilas-Zornoza, A.; Martinez-de-Morentin, X.; Lasaga, M.; Alignani, D.; Pavia, B.; Vinado, A. C.; San Martin-Uriz, P.; Romero, J. P.; Quilez Agreda, D.; MinanaBarrios, M.; Sancho-Gonzalez, I.; Todisco, G.; Malcovati, L.; Planell, N.; Saez, B.; Tegner, J.; Prosper, F.; Gomez-Cabrero, D.

10.1101/2021.07.17.452614 — immunology — Posted on 2021-07-17

1801 TREM2 impacts brain microglia, oligodendrocytes and endothelial co-expression modules revealing genes and pathways important in Alzheimer s disease

Carbajosa, G.; Malki, K.; Lawless, N.; Wang, H.; Ryder, J. W.; Wood, K.; Mein, C. A.; Hodgkinson, A.; Dobson, R. J. B.; Collier, D. A.; ONeill, M.; Newhouse, S. J.; Hodges, A. K.

10.1101/2021.07.16.452732 — neuroscience — Posted on 2021-07-17

1802 DNA sliding and loop formation by E. coli SMC complex: MukBEF

zhou, m.

10.1101/2021.07.17.452765 — biophysics — Posted on 2021-07-17

1803 A model-based approach to characterize enzyme-mediated response to antibiotic treatments: going beyond the SIR classification

Andreani, V.; You, L.; Glaser, P.; Batt, G.

10.1101/2021.07.16.452741 — biophysics — Posted on 2021-07-17

1804 The adaptation front equation explains diversification hotspots and living-fossilization

Ito, H. C.; Sasaki, A.

10.1101/2021.07.17.452749 — evolutionary biology — Posted on 2021-07-17

1805 microRNAs Over-expressed in Diabetic Foot Ulcers Healing - Computational Modeling of Molecular Structure

de Oliveira Andrade, L. J.; Vinhaes Bittencourt, A. M.; Matos de Oliveira, L.; Matos de Oliveira, G. C.

10.1101/2021.07.16.452675 — molecular biology — Posted on 2021-07-17

1806 Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma

Lu, X.; Sabbasani, V. R.; Osei-Amponsa, V.; Evans, C. N.; King, J. C.; Tarasov, S. G.; Dyba, M.; Chan, K. C.; Schwieters, C. D.; Choudhari, S.; Fromont, C.; Zhao, Y.; Tran, B.; Chen, X.; Matsuo, H.; Andresson, T.; Chari, R.; Swenson, R. E.; Tarasova, N. I.; Walters, K. J.

10.1101/2021.07.16.452547 — molecular biology — Posted on 2021-07-17

1807 Pathogenic potential in catheter associated Escherichia coli is associated with separable biofilm and virulence gene determinants

Zou, Z.; Potter, R.; McCoy, W.; Katumba, G.; Mucha, P. J.; Dantas, G.; Henderson, J. P.

10.1101/2021.07.16.452752 — microbiology — Posted on 2021-07-17

1808 A subcellular biochemical model for T6SS dynamics reveals winning competitive strategies

Lin, Y. L.; Smith, S. N.; Kanso, E.; Septer, A. N.; Rycroft, C. H.

10.1101/2021.07.17.452664 — microbiology — Posted on 2021-07-17

1809 The M2 Gene Is a Determinant of Reovirus-Induced Myocarditis

Dina Zita, M.; Phillips, M. B.; Stuart, J. D.; Kumarapeli, A. R.; Sridharan, V.; Boerma, M.; Snyder, A. J.; Danthi, P.; Boehme, K. W.

10.1101/2021.07.16.452757 — microbiology — Posted on 2021-07-17

1810 Quantification of Myxococcus xanthus Aggregation and Rippling Behaviors: Deep-learning Transformation of Phase-contrast into Fluorescence Microscopy Images

Zhang, J.; Comstock, J. A.; Cotter, C. R.; Murphy, P. A.; Nie, W.; Welch, R. D.; Patel, A. B.; Igoshin, O. A.

10.1101/2021.07.16.452736 — systems biology — Posted on 2021-07-17

1811 Structural and functional characterization of ubiquitin variant inhibitors for the JAMM-family deubiquitinases STAMBP and STAMBPL1

Guo, Y.; Liu, Q.; Mallette, E.; Caba, C.; Hou, F.; Fux, J.; LaPlante, G.; Dong, A.; Zhang, Q.; Zheng, H.; Tong, Y.; Zhang, W.

10.1101/2021.07.16.452720 — biochemistry — Posted on 2021-07-17

1812 Tillage intensity and plant rhizosphere selection shape bacterial-archaeal assemblage diversity and nitrogen cycling genes

Cloutier, M. L. C.; Alcaide, T.; Duiker, S. W.; Bruns, M. A.

10.1101/2021.07.16.452714 — microbiology — Posted on 2021-07-17

1813 Cellular translational enhancer elements that recruit eukaryotic initiation factor 3

Koubek, J.; Niederer, R.; Stanciu, A.; Aitken, C. E.; Gilbert, W. V.

10.1101/2021.07.15.452589 — systems biology — Posted on 2021-07-17

1814 The HDL particle composition determines its anti-tumor activity in pancreatic cancer

Bauer, R.; Kuehrer, K. M.; Udonta, F.; Wroblewski, M.; Ben-Batalla, I.; Hassl, I.; Körbelin, J.; Röhrl, C.; Unseld, M.; Jauhiainen, M.; Hengstschläger, M.; Loges, S.; Stangl, H.

10.1101/2021.07.16.452627 — cancer biology — Posted on 2021-07-17

1815 The interplay of RNA:DNA hybrid structure and G-quadruplexes determines the outcome of R-loop-replisome collisions

Kumar, C.; Batra, S.; Griffith, J.; Remus, D.

10.1101/2021.07.16.452753 — biochemistry — Posted on 2021-07-17

1816 Cooperative DNA base and shape recognition by the CCAAT-binding complex and its bZIP transcription factor HapX

Huber, E. M.; Hortschansky, P.; Scheven, M. T.; Misslinger, M.; Haas, H.; Brakhage, A. A.; Groll, M.

10.1101/2021.07.15.452465 — biochemistry — Posted on 2021-07-17

1817 Allosteric control of Ubp6 and the proteasome via a bidirectional switch

Hung, K. Y. S.; Klumpe, S.; Eisele, M. R.; Elsasser, S.; Tian, G.; Sun, S.; Moroco, J. A.; Cheng, T. C.; Joshi, T.; Seibel, T.; Van Dalen, D.; Feng, X.-H.; Lu, Y.; Ovaa, H.; Engen, J. R.; Lee, B.-H.; Rudack, T.; Sakata, E.; Finley, D.

10.1101/2021.07.16.452743 — biochemistry — Posted on 2021-07-17

1818 Identification of a novel Candida metapsilosis isolate suggests ongoing hybridization.

O'Brien, C. E.; Zhai, B.; Ola, M.; O Cinneide, E.; O'Connor, I.; Rolling, T.; Miranda, E.; Babady, N. E.; Hohl, T. M.; Butler, G.

10.1101/2021.07.15.452539 — genomics — Posted on 2021-07-17

1819 SnoRNA guide activities-real and ambiguous

Deryusheva, S.; Talross, G. J.; Gall, J. G.

10.1101/2021.07.15.452550 — molecular biology — Posted on 2021-07-17

1820 Unravelling the puzzle of anthranoids metabolism in living plant cells using spectral imaging coupled to mass spectrometry

Chevalier, Q.; Galle, J.-B.; Wasser, N.; Mazan, V.; Villette, C.; Mutterer, J.; Elustondo, M. M.; Girard, N.; Elhabiri, M.; Schaller, H.; Hemmerlin, A. M.; Vonthron-Senecheau, C.

10.1101/2021.07.15.452517 — plant biology — Posted on 2021-07-17

1821 Interpersonal synchronization of movement intermittency

Tomassini, A.; Laroche, J.; Emanuele, M.; Nazzaro, G.; Petrone, N.; Fadiga, L.; D'Ausilio, A.

10.1101/2021.06.09.447663 — neuroscience — Posted on 2021-07-17

1822 The Series of a Four-node Motif and Coherent Type-1 Feed-forward Loop can Provide Sensitive Detection over Arbitrary Range of Input Signal, thereby Explain Weber's Law in Higher-Order Sensory Processes, and Compute Logarithm

Wadhwa, D.

10.1101/2020.04.08.032193 — systems biology — Posted on 2021-07-17

1823 Accurate Automatic Glioma Segmentation in Brain MRI images Based on CapsNet

Jalili Aziz, M.; Amiri Tehrani Zade, A.; Farnia, P.; Alimohammadi, M.; Makki Abadi, B.; Ahmadian, A.; Alirezaie, J.

10.1101/2021.07.03.450931 — bioengineering — Posted on 2021-07-17

1824 Cation-chloride cotransporters, Na/K pump, and channels in cell water and ions regulation: in silico and experimental studies of the U937 cells under stopping the pump and during RVD

Vereninov, A. A.; Yurinskaya, V.

10.1101/2021.07.10.451878 — cell biology — Posted on 2021-07-17

1825 Coupling of pupil- and neuronal population dynamics reveals diverse influences of arousal on cortical processing

Pfeffer, T.; Keitel, C.; Kluger, D. S.; Keitel, A.; Russmann, A.; Thut, G.; Donner, T. H.; Gross, J.

10.1101/2021.06.25.449734 — neuroscience — Posted on 2021-07-17

1826 Agonism and grooming behavior explain social status effects on physiology and gene regulation in rhesus macaques

Simons, N. D.; Michopoulos, V.; Wilson, M.; Barreiro, L. B.; Tung, J.

10.1101/2021.07.16.452731 — genomics — Posted on 2021-07-17

1827 The impact of whole genome duplications on the human gene regulatory networks

Mottes, F.; Villa, C.; Osella, M.; Caselle, M.

10.1101/2021.07.16.452729 — systems biology — Posted on 2021-07-17

1828 Mapping the vocal circuitry of Alston's singing mouse with pseudorabies virus

Zheng, D.-J.; Okobi, D. E.; Shu, R.; Agrawal, R.; Smith, S. K.; Long, M. A.; Phelps, S. M.

10.1101/2021.07.16.452718 — neuroscience — Posted on 2021-07-17

1829 The pathogen-encoded signaling receptor Tir exploits host-like intrinsic disorder to assist infection

Vieira, M. F. M.; Hernandez, G.; Veloso, T.; Monteiro, H.; Arbesu, M.; Zanzoni, A.; Cordeiro, T. N.

10.1101/2021.04.22.440577 — biophysics — Posted on 2021-07-17

1830 Define and visualize pathological architectures of human tissues from spatially resolved transcriptomics using deep learning

Chang, Y.; He, F.; Wang, J.; Chen, S.; Li, J.; Liu, J.; Yu, Y.; Su, L.; Ma, A.; Allen, C.; Lin, Y.; Sun, S.; Liu, B.; Otero, J.; Chung, D.; Fu, H.; Li, Z.; Xu, D.; Ma, Q.

10.1101/2021.07.08.451210 — bioinformatics — Posted on 2021-07-16

1831 Ecological opportunity, radiation events and genomic innovations shaped the episodic evolutionary history of papillomaviruses

Willemsen, A.; Bravo, I. G.

10.1101/2020.03.08.982421 — evolutionary biology — Posted on 2021-07-16

1832 Liberation from fibrogenesis or tumorigenesis via cellular senescence by a novel small molecule

Youn, B.-S.; Meang, M. K.; Kim, S.

10.1101/2021.06.01.446522 — cell biology — Posted on 2021-07-16

1833 Development of antibiotic resistance reveals diverse evolutionary pathways to face the complex and dynamic environment of a long-term treated patient

Colque, C. A.; Tomatis, P. E.; Albarracin Orio, A. G.; Dotta, G.; Moreno, D. M.; Hedemann, L. G.; Hickman, R. A.; Sommer, L. M.; Feliziani, S.; Moyano, A. M.; Bonomo, R. A.; Johansen, H. K.; Molin, S.; Vila, A. J.; Smania, A. M.

10.1101/2021.05.14.444257 — microbiology — Posted on 2021-07-16

1834 The developmental changes in intrinsic and synaptic properties of prefrontal neurons enhance local network activity from the second to the third postnatal week

Kalemaki, K.; Velli, A.; Christodoulou, O.; Denaxa, M.; Sidiropoulou, K.; Karagogeos, D.

10.1101/2020.01.21.913913 — neuroscience — Posted on 2021-07-16

1835 Trips and Neurotransmitters: Discovering Principled Patterns across 6,850 Hallucinogenic Experiences

Ballentine, G.; Friedman, S. F.; Bzdok, D.

10.1101/2021.07.13.452263 — neuroscience — Posted on 2021-07-16

1836 Multi-Modal Data Analysis for Alzheimer's Disease Diagnosis: An Ensemble Model Using Imagery and Genetic Features

Ying, Q.; Xing, X.; Liu, L.; Lin, A.-L.; Jacobs, N.; Liang, G.

10.1101/2021.05.07.443184 — neuroscience — Posted on 2021-07-16

1837 An information theoretic method to resolve millisecond-scale spike timing precision in a comprehensive motor program

Putney, J.; Niebur, T.; Conn, R.; Sponberg, S.

10.1101/2021.07.14.452403 — neuroscience — Posted on 2021-07-16

1838 Posttranslational modification of the RHO of plants protein RACB by phosphorylation and cross-kingdom conserved ubiquitination

Weiss, L.; Reiner, T.; Mergner, J.; Kuster, B.; Feher, A.; Hensel, G.; Gahrtz, M.; Kumlehn, J.; Engelhardt, S.; Huckelhoven, R.

10.1101/2020.05.28.121228 — plant biology — Posted on 2021-07-16

1839 In vivo profiling of site-specific human cancer cell states in zebrafish

Segal, D.; Mazloom-Farsibaf, H.; Chang, B.-J.; Roudot, P.; Rajendran, D.; Warren, M.; Fiolka, R.; Amatruda, J.; Danuser, G.

10.1101/2021.06.09.447621 — cancer biology — Posted on 2021-07-16

1840 Quantifying ERK-activity in response to inhibition of the BRAFV600E-MEK-ERK cascade using mathematical modelling

Hamis, S.; Kapelyukh, Y.; McLaren, A.; Henderson, C. J.; Wolf, C. R.; Chaplain, M. A. J.

10.1101/2021.04.20.440559 — cancer biology — Posted on 2021-07-16

1841 AdRoit: an accurate and robust method to infer complex transcriptome composition

Yang, T.; Alessandri-Haber, N.; Fury, W.; Schaner, M.; Breese, R.; LaCroix-Fralish, M.; Kim, J.; Adler, C.; Macdonald, L. E.; Atwal, G. S.; Bai, Y.

10.1101/2020.12.14.422697 — bioinformatics — Posted on 2021-07-16

1842 Non-Newtonian Patient-specific Simulations of Left Atrial Hemodynamics

Gonzalo, A.; Garcia-Villalba, M.; Rossini, L.; Duran, E.; Vigneault, D.; Martinez-Legazpi, P.; Flores, O.; Bermejo, J.; McVeigh, E.; Kahn, A.; del Alamo, J. C.

10.1101/2021.06.24.449801 — bioengineering — Posted on 2021-07-16

1843 One Cell At a Time: A Unified Framework to Integrate and Analyze Single-cell RNA-seq Data

Wang, C. X.; Zhang, L.; Wang, B.

10.1101/2021.05.12.443814 — genomics — Posted on 2021-07-16

1844 The parasite Schistocephalus solidus secretes proteins with putative host manipulation functions

Berger, C. S.; Laroche, J.; Maaroufi, H.; Martin, H.; Moon, K.-M.; Landry, C.; Foster, L.; Aubin-Horth, N.

10.1101/2020.02.03.932509 — genomics — Posted on 2021-07-16

1845 Diverse wMel variants of Wolbachia pipientis differentially rescue fertility and cytological defects of the bag of marbles partial loss of function mutation in Drosophila melanogaster

Bubnell, J. E.; Fernandez Begne, P.; Ulbing, C. K. S.; Aquadro, C. F.

10.1101/2021.01.15.426050 — genetics — Posted on 2021-07-16

1846 High-resolution single cell transcriptome analysis of zebrafish sensory hair cell regeneration

Baek, S.; Tran, N. T. T.; Diaz, D. C.; Tsai, Y.-Y.; Navajas Acedo, J.; Lush, M. E.; Piotrowski, T.

10.1101/2021.07.15.452338 — developmental biology — Posted on 2021-07-16

1847 Differential regulation of mRNA fate by the human Ccr4-Not complex is driven by CDS composition and mRNA localisation

Gillen, S. L.; Giacomelli, C.; Hodge, K.; Zanivan, S.; Bushell, M.; Wilczynska, A.

10.1101/2021.03.13.435226 — molecular biology — Posted on 2021-07-16

1848 Myonuclear maturation dynamics in aged and adult regenerating mouse skeletal muscle

Kurland, J. V.; Deusen, A. V.; Pawlikowski, B.; Hall, M.; Betta, N. D.; Antwine, T.; Cutler, A. A.; Russell, A.; Allen, M. A.; Dowell, R. D.; Olwin, B. B.

10.1101/2021.07.13.452218 — molecular biology — Posted on 2021-07-16

1849 Functional characterisation of banana (Musa spp.) 2-oxoglutarate-dependent dioxygenases involved in flavonoid biosynthesis

Busche, M.; Acatay, C.; Martens, S.; Weisshaar, B.; Stracke, R.

10.1101/2021.05.03.442406 — molecular biology — Posted on 2021-07-16

1850 Gut regulatory T cells mediate immunological tolerance in Salmonella Typhimurium-infected superspreader hosts by suppressing cytotoxic activity of T cells.

Moura Massis, L.; Ruddle, S.; Brewer, S. M.; Schade, R.; Narasimhan, R.; Honeycutt, J. D.; Pham, T. H.; McKenna, J. A.; Brubaker, S. W.; Chairatana, P.; Klein, J. A.; Margalef-Catala, M. d. M.; Amieva, M. R.; Vilches-Moure, J. G.; Monack, D. M.

10.1101/2021.07.16.452606 — immunology — Posted on 2021-07-16

1851 Nanoscopical analysis reveals an orderly arrangement of the presynaptic scaffold protein Bassoon at the Golgi-apparatus

Ghelani, T.; Venegas, C. M.; Fejtova, A.; Dresbach, T.

10.1101/2021.06.28.450125 — neuroscience — Posted on 2021-07-16

1852 Temporal pattern and synergy influence activity of ERK signaling pathways during L-LTP induction

Miningou Zobon, N. T.; Jedrzejewska-Szmek, J.; Blackwell, K. T.

10.1101/2020.11.04.368571 — neuroscience — Posted on 2021-07-16

1853 Tau modulates mRNA transcription, alternative polyadenylation profiles of hnRNPs, chromatin remodeling and spliceosome complexes

Montalbano, M.; Jaworski, E.; Garcia, S.; Ellsworth, A.; McAllen, S.; Routh, A.; Kayed, R.

10.1101/2021.07.16.452616 — neuroscience — Posted on 2021-07-16

1854 Braiding Braak and Braak: Staging patterns and model selection in network neurodegeneration

Putra, P.; Thompson, T. B.; Chaggar, P.; Goriely, A.

10.1101/2021.01.21.427609 — neuroscience — Posted on 2021-07-16

1855 ALG-2 interacting protein-X (Alix) is required for activity-dependent bulk endocytosis at brain synapses

Laporte, M. H.; Chi, K. I.; Rolland, M.; Caudal, L. C.; Martinez-Hernandez, J.; Martineau, M.; Chatellard, C.; Denarier, E.; Mercier, V.; Lemaitre, F.; Blot, B.; Moutaux, E.; Cazorla, M.; Perrais, D.; Fraboulet, S.; Lante, F.; Kirchhoff, F.; Hemming, F. J.; Sadoul, R.

10.1101/2020.07.20.211854 — neuroscience — Posted on 2021-07-16

1856 Multivariate Pattern Analysis (MVPA) Reveals Distinct Neural Profiles of Frontoparietal Networks in Boys with Attention-Deficit/Hyperactivity Disorder and Boys with Persistent Depressive Disorder

Vilgis, V.; Yee, D. M.; Silk, T.; Vance, A.

10.1101/2021.03.09.434662 — neuroscience — Posted on 2021-07-16

1857 A Population Receptive Field Model of the Magnetoencephalography Response

Kupers, E. R.; Edadan, A.; Benson, N. C.; Zuiderbaan, W.; De Jong, M. C.; Dumoulin, S. O.; Winawer, J.

10.1101/2020.08.28.272534 — neuroscience — Posted on 2021-07-16

1858 Cell fitness is an omniphenotype

Jacobs, N. C.; Park, J.; Saccone, N. L.; Peterson, T. R.

10.1101/487157 — systems biology — Posted on 2021-07-16

1859 Understanding hydropower impacts on Amazonian wildlife is limited by a lack of robust evidence: results from a systematic review

Rodrigues dos Santos, E.; Michalski, F.; Norris, D.

10.1101/2021.07.01.450737 — scientific communication and education — Posted on 2021-07-16

1860 Loss of Endothelial HIF-Prolyl hydroxylase 2 (PHD2) Induces Cardiac Hypertrophy and Fibrosis

Dai, Z.; Cheng, J.; Liu, B.; Yi, D.; Feng, A.; Wang, T.; Gao, C.; Wang, Y.; Zhu, M. M.; Zhang, X.; Zhao, Y.

10.1101/2021.03.19.434301 — physiology — Posted on 2021-07-16

1861 Inducing oncolytic cell death in human cancer cells by the long non-coding RNA let-A

Birbaumer, T.; Schlumpf, T. B.; Seimiya, M.; Jiang, Y.; Paro, R.

10.1101/2021.07.16.452707 — cancer biology — Posted on 2021-07-16

1862 An Omic and Multidimensional Spatial Atlas from Serial Biopsies of an Evolving Metastatic Breast Cancer

Johnson, B. E.; Creason, A. L.; Stommel, J. M.; Keck, J. M.; Parmar, S.; Betts, C. B.; Blucher, A.; Boniface, C.; Bucher, E.; Burlingame, E. A.; Camp, T.; Chin, K.; Eng, J.; Estabrook, J.; Feiler, H. S.; Hu, Z.; Kolodzie, A.; Kong, B. L.; Labrie, M.; Lee, J.; Leyshock, P.; Mitri, S.; Patterson, J.; Riesterer, J. L.; Sivagnanam, S.; Somers, J.; Sudar, D.; Thibault, G.; Zheng, C.; Nan, X.; Heiser, L. M.; Spellman, P. T.; Thomas, G. V.; Demir, E.; Chang, Y. H.; Coussens, L. M.; Guimaraes, A. R.; Corless, C.; Goecks, J.; Bergan, R.; Mitri, Z.; Mills, G. B.; Gray, J. W.

10.1101/2020.12.03.408500 — cancer biology — Posted on 2021-07-16

1863 PhyloCSF++: A fast and user-friendly implementation of PhyloCSF with annotation tools

Pockrandt, C.; Steinegger, M.; Salzberg, S.

10.1101/2021.03.10.434297 — bioinformatics — Posted on 2021-07-16

1864 Estimating RNA dynamics using one time point for one sample in a single-pulse metabolic experiment

Hersch, M.; Biasini, A.; Marques, A.; Bergmann, S.

10.1101/2020.05.01.071779 — bioinformatics — Posted on 2021-07-16

1865 Classification of Free-Living Body Posture with ECG Patch Accelerometers: Application to the Multicenter AIDS Cohort Study

Etzkorn, L. H.; Heravi, A. S.; Wu, K. C.; Post, W. S.; Urbanek, J. K.; Crainiceanu, C.

10.1101/2021.07.16.452654 — bioengineering — Posted on 2021-07-16

1866 In-situ genomic prediction using low-coverage Nanopore sequencing

Lamb, H.; Hayes, B.; Randhawa, I.; Nguyen, L.; Ross, E.

10.1101/2021.07.16.452615 — genetics — Posted on 2021-07-16

1867 The evolution of mechanisms to produce phenotypic heterogeneity in microorganisms

Cooper, G. A.; Liu, M.; Pena, J.; West, S. A.

10.1101/2020.02.25.964643 — evolutionary biology — Posted on 2021-07-16

1868 Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner

Hwang, S.-h.; Somatilaka, B. N.; White, K.; Mukhopadhyay, S.

10.1101/2021.01.07.425654 — developmental biology — Posted on 2021-07-16

1869 Mechanisms of genetic instability in a single S-phase following whole genome doubling

Gemble, S.; Bernhard, S. V.; Srivastava, N.; Wardenaar, R.; Nano, M.; Mace, A.-S.; Tijhuis, A.; Keuper, K.; Spierings, D. C. J.; Hochegger, H.; Piel, M.; Foijer, F.; Storchova, Z.; Basto, R.

10.1101/2021.07.16.452672 — cell biology — Posted on 2021-07-16

1870 Autophagosomes fuse to phagosomes and play important roles in the degradation of apoptotic cells in Caenorhabditis elegans

Pena-Ramos, O.; Chiao, L.; Liu, X.; Yao, T.; He, H.; Zhou, Z.

10.1101/2021.07.16.452694 — cell biology — Posted on 2021-07-16

1871 Asymmetric Arp2/3-mediated actin assembly facilitates clathrin-mediated endocytosis at stalled sites in genome-edited human stem cells.

Jin, M.; Shirazinejad, C.; Wang, B.; Yan, A.; Schöneberg, J.; Upadhyayula, S.; Xu, K.; Drubin, D. G.

10.1101/2021.07.16.452693 — cell biology — Posted on 2021-07-16

1872 Crosstalk between chloroplast protein import and the SUMO system revealed through genetic and molecular investigation

Watson, S.; Li, N.; Ye, Y.; Wu, F.; Ling, Q.; Jarvis, R. P.

10.1101/2020.07.21.213355 — cell biology — Posted on 2021-07-16

1873 Accurate Direct PCR with Arabidopsis and rice

Lynagh, P.; Hungsaprug, K.; Osuna-Kleist, P.; Malagon, E.; Tan, E. H.; Comai, L.

10.1101/2021.07.16.452406 — molecular biology — Posted on 2021-07-16

1874 A study of the correlation between phenotypic antimicrobial susceptibility testing methods and the associated genotypes determined by whole genome sequencing for a collection of Escherichia coli of bovine origin

Maunsell, T. J.; Nguyen, S.; El Garach, F.; Miossec, C.; Cuinet, E.; Woehrle, F.; Fanning, S.; Niedziela, D. A.

10.1101/2021.07.16.452668 — microbiology — Posted on 2021-07-16

1875 Phenotypic determinism and stochasticity in antibody repertoires of clonally expanded plasma cells

Neumeier, D.; Yermanos, A.; Agrafiotis, A.; Csepregi, L.; Chowdhury, T.; Ehling, R. A.; Kuhn, R.; Brisset-Di Roberto, R.; Di Tacchio, M.; Antonialli, R.; Starkie, D.; Lightwood, D. J.; Oxenius, A.; Reddy, S. T.

10.1101/2021.07.16.452687 — immunology — Posted on 2021-07-16

1876 Enhancing Task fMRI Preprocessing via Individualized Model-Based Filtering of Intrinsic Activity Dynamics

Singh, M. F.; Wang, A.; Cole, M.; Ching, S.; Braver, T. S.

10.1101/2020.12.10.420273 — neuroscience — Posted on 2021-07-16

1877 Structural and functional analysis of lorlatinib analogs reveals roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer

Shiba-Ishii, A.; Johnson, T. W.; Dagogo-Jack, I.; Mino-Kenudson, M.; Johnson, T. R.; Wei, P.; Weinrich, S. L.; McTigue, M. A.; Walcott, M. A.; Nguyen-Phuong, L.; Dionne, K.; Acker, A.; Kiedrowski, L.; Do, A.; Peterson, J. L.; Barth, J. L.; Yeap, B. Y.; Gainor, J. F.; Lin, J. J.; Yoda, S.; Hata, A. N.

10.1101/2021.07.16.452681 — cancer biology — Posted on 2021-07-16

1878 Epigenetic regulator genes direct lineage switching in MLL-AF4 leukaemia

Tirtakusuma, R.; Szoltysek, K.; Milne, P.; Grinev, V. V.; Ptasinska, A.; Meyer, C.; Nakjang, S.; Hehir-Kwa, J. Y.; Williamson, D.; Cauchy, P.; Assi, S. A.; Imperato, M. R.; Vogiatzi, F.; Lin, S.; Wunderlich, M.; Stutterheim, J.; Komkov, A.; Zerkalenkova, E.; Evans, P.; McNeill, H.; Elder, A.; Martinez Soria, N.; Fordham, S. E.; Shi, Y.; Russell, L. J.; Pal, D.; Smith, A.; Kingsbury, Z.; Becq, J.; Eckert, C.; Haas, O. A.; Carey, P.; Bailey, S.; Skinner, R.; Miakova, N.; Collin, M.; Bigley, V.; Haniffa, M.; Marschalek, R.; Harrison, C. J.; Cargo, C. A.; Schewe, D.; Olshanskaya, Y.; Thirman, M. J

10.1101/2021.07.16.452676 — cancer biology — Posted on 2021-07-16

1879 Combining ancestral reconstruction with folding-landscape simulations to engineer heterologous protein expression

Gamiz-Arco, G.; Risso, V. A.; Gaucher, E. A.; Gavira, J. A.; Naganathan, A. N.; Ibarra-Molero, B.; Sanchez-Ruiz, J. M.

10.1101/2021.07.16.452635 — biophysics — Posted on 2021-07-16

1880 Potentialities of biotechnological recovery of hydrogen and short- and medium-chainorganic acids from the co-fermentation of cheese whey and Yerba Mate (Ilexparaguariensis) waste

Ferraz, A. D. N.; Fuentes, L.; de la Sovera, V.; Bovio-Winkler, P.; Eng, F.; Garcia, M.; Etchebehere, C.

10.1101/2021.07.16.452613 — biochemistry — Posted on 2021-07-16

1881 Cellular and genetic drivers of RNA editing variation in the human brain

Cuddleston, R.; Li, J.; Fan, X.; Kozenkov, A.; Lalli, M.; Khalique, S.; Dracheva, S.; Mukamel, E. A.; Breen, M. S.

10.1101/2021.07.16.452690 — genetics — Posted on 2021-07-16

1882 TIGAR-V2: Efficient TWAS Tool with Nonparametric Bayesian eQTL Weights of 49 Tissue Types from GTEx V8

Parrish, R. L.; Gibson, G. C.; Epstein, M. P.; Yang, J.

10.1101/2021.07.16.452700 — genetics — Posted on 2021-07-16

1883 Deforestation projections imply range-wide population decline for critically endangered Bornean orangutan

Voigt, M.; Kühl, H. S.; Ancrenaz, M.; Gaveau, D.; Meijaard, E.; Santika, T.; Sherman, J.; Wich, S. A.; Wolf, F.; Struebig, M. j.; Pereira, H. M.; Rosa, I. M.

10.1101/2021.07.16.451448 — ecology — Posted on 2021-07-16

1884 Very Long-Chain Unsaturated Sphingolipids Mediate Oleate-Induced Rat β-Cell Proliferation

Castell, A.-L.; Vivoli, A.; Tippetts, T. S.; Robillard Frayne, I.; Moulle, V. S.; Ruiz, M.; Ghislain, J.; Des Rosiers, C.; Holland, W. L.; Summers, S. A.; Poitout, V.

10.1101/2021.07.16.452686 — cell biology — Posted on 2021-07-16

1885 The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model

Yuste-Checa, P.; Trinkaus, V. A.; Riera-Tur, I.; Imamoglu, R.; Schaller, T.; Wang, H.; Dudanova, I.; Hipp, M. S.; Bracher, A.; Hartl, F. U.

10.1101/2021.07.16.452659 — cell biology — Posted on 2021-07-16

1886 Airborne environmental DNA for terrestrial vertebrate community monitoring

Lynggaard, C.; Bertelsen, M. F.; Jensen, C. V.; Johnson, M. S.; Froslev, T. G.; Olsen, M. T.; Bohmann, K.

10.1101/2021.07.16.452634 — molecular biology — Posted on 2021-07-16

1887 Significant Variability exists in the Toxicity of Global Methicillin-resistant Staphylococcus aureus Lineages.

Laabei, M.; Peacock, S.; Blane, B.; Baines, S. L.; Stinear, T. P.; Howden, B.; Massey, R. C.

10.1101/2021.07.16.452633 — microbiology — Posted on 2021-07-16

1888 A flexible Bayesian approach to estimating size-structured matrix population models

Mattern, J. P.; Glauninger, K.; Britten, G. L.; Casey, J.; Hyun, S.; Wu, Z.; Armbrust, E. V.; Harchaoui, Z.; Ribalet, F.

10.1101/2021.07.16.452528 — microbiology — Posted on 2021-07-16

1889 Beneficial Lactiplantibacillus plantarum promote Drosophila growth by down-regulating the expression of PGRP-SC1

Gallo, M.; Vento, J.; Joncour, P.; Quagliariello, A.; Maritan, E.; Beisel, C.; Martino, M. E.

10.1101/2021.07.16.452638 — microbiology — Posted on 2021-07-16

1890 Exploring the human cerebral cortex using confocal microscopy

Pesce, L.; Laurino, A.; Scardigli, M.; Yang, J.; Boas, D. A.; Hof, P. R.; Destrieux, C.; Costantini, I.; Pavone, F. S.

10.1101/2021.07.16.452651 — neuroscience — Posted on 2021-07-16

1891 Neurotoxins subvert the allosteric activation mechanism of SARM1 to induce neuronal loss

Wu, T.; Zhu, J.; Strickland, A.; Ko, K. W.; Sasaki, Y.; Dingwall, C.; Yamada, Y.; Figley, M. D.; Mao, X.; Neiner, A.; Bloom, J.; DiAntonio, A.; Milbrandt, J.

10.1101/2021.07.16.452689 — neuroscience — Posted on 2021-07-16

1892 GAIT-GM integrative cross-omics analyses reveal cholinergic defects in a C. elegans model of Parkinson's disease

Mor, D. E.; Huertas, F.; Morse, A. M.; Kaletsky, R.; Murphy, C. T.; Kalia, V.; Miller, G. W.; Moskalenko, O.; Conesa, A.; McIntyre, L. M.

10.1101/2021.07.16.452702 — neuroscience — Posted on 2021-07-16

1893 Ultrafast population coding and axo-somatic compartmentalization

Zhang, C.; Hofmann, D.; Neef, A.; Wolf, F.

10.1101/2021.07.16.452655 — neuroscience — Posted on 2021-07-16

1894 Visualizing Amino Acid Substitutions in a Physicochemical Vector Space

Nemzer, L. R.

10.1101/2021.07.15.452549 — bioinformatics — Posted on 2021-07-16

1895 Antithrombin glycoforms from type II antithrombin deficient patients selectively adsorb onto the surface of plasma extracellular vesicles

Radeghieri, A.; Alacqua, S.; Zendrini, A.; Previcini, V.; Todaro, F.; Martini, G.; Ricotta, D.; Bergese, P.

10.1101/2021.07.16.452649 — biochemistry — Posted on 2021-07-16

1896 Tensin3 interaction with talin drives formationof fibronectin-associated fibrillar adhesions

Atherton, P.; Konstantinou, R.; Neo, S. P.; Wang, E.; Balloi, E.; Ptushkina, M.; Bennett, H.; Clark, K.; Gunaratne, J.; Critchley, D.; Barsukov, I.; Manser, E.; Ballestrem, C.

10.1101/2021.07.16.452612 — cell biology — Posted on 2021-07-16

1897 Regeneration of Plants from DNA-free Edited Grapevine Protoplasts

Scintilla, S.; Salvagnin, U.; Giacomelli, L.; Zeilmaker, T.; Malnoy, M. A.; Rouppe van der Voort, J.; Moser, C.

10.1101/2021.07.16.452503 — plant biology — Posted on 2021-07-16

1898 A long non-coding RNA in the let-7 complex acting as a potent and specific death effector of cancer cells

Birbaumer, T.; Schlumpf, T. B.; Seimiya, M.; Jiang, Y.; Paro, R.

10.1101/2021.07.16.452600 — cancer biology — Posted on 2021-07-16

1899 Transcriptomic analysis of mdx mouse muscles reveals a signature of early human Duchenne muscular dystrophy

Ralston, E.; Gutierrez-Cruz, G.; Kenea, A. D.; Brooks, S. R.

10.1101/2021.07.16.452553 — genetics — Posted on 2021-07-16

1900 Efficient Estimation of Indirect Effects in Case-Control Studies Using a Unified Likelihood Framework

Satten, G. A.; Curtis, S. W.; Solis-Lemus, C.; Leslie, E. J.; Epstein, M.

10.1101/2021.07.16.452552 — genetics — Posted on 2021-07-16

1901 Long-term ecosystem nitrogen limitation from foliar δ15N data and a land surface model

Caldararu, S.; Thum, T.; Yu, L.; Kern, M.; Nair, R.; Zaehle, S.

10.1101/2021.07.16.452605 — ecology — Posted on 2021-07-16

1902 Intestinal organoids expose heterogeneity in SARS-CoV-2 susceptibility

Jang, K. K.; Kaczmarek, M. E.; Dallari, S.; Chen, Y.-H.; Axelrad, J.; Stapleford, K. A.; Cadwell, K.

10.1101/2021.07.16.452680 — cell biology — Posted on 2021-07-16

1903 Darwin's bark spider shares a spidroin repertoire with Caerostris extrusa but achieves extraordinary silk toughness through gene expression

Kono, N.; Ohtoshi, R.; Malay, A. D.; Mori, M.; Masunaga, H.; Yoshida, Y.; Nakamura, H.; Numata, K.; Arakawa, K.

10.1101/2021.07.16.452619 — molecular biology — Posted on 2021-07-16

1904 Creating detailed metadata for an R Shiny analysis of circadian behavior sequence data

Winter, Y.; Colomb, J.

10.1101/2021.07.16.452645 — neuroscience — Posted on 2021-07-16

1905 Non-genetic maternal effects shape individual differences in cortisol phenotypes in wild chimpanzees

Tkaczynski, P. J.; Mafessoni, F.; Girard-Buttoz, C.; Samuni, L.; Ackermann, C. Y.; Fedurek, P.; Gomes, C.; Hobaiter, C.; Lohrich, T.; Manin, V.; Preis, A.; Vale, P.; Wessling, E. G.; Wittiger, L.; Zommers, Z.; Zuberbuehler, K.; Vigilant, L.; Deschner, T.; Wittig, R. M.; Crockford, C.

10.1101/2021.07.16.452609 — zoology — Posted on 2021-07-16

1906 Ultraviolet screening by slug tissue and tight packing of plastids protect photosynthetic sea slugs from photoinhibition

Havurinne, V.; Aitokari, R.; Mattila, H.; Käpylä, V.; Tyystjärvi, E.

10.1101/2021.07.15.452583 — plant biology — Posted on 2021-07-16

1907 TaBln1 negatively regulates wheat resistance to stripe rust by reducing Ca2+ influx

Guo, S.; Zhang, Y.; Zeng, P.; Li, M.; Zhang, Q.; Li, X.; Xu, Q.; Li, T.; Wang, X.; Kang, Z.; Zhang, X.

10.1101/2021.07.16.452683 — pathology — Posted on 2021-07-16

1908 Obsessive Compulsive Disorder and Response Inhibition: Meta-analysis of the Stop-Signal Task

Mar, K.; Townes, P.; Pechlivanoglou, P.; Arnold, P.; Schachar, R. J.

10.1101/2021.07.16.452538 — pathology — Posted on 2021-07-16

1909 Hepatoblastomas with carcinoma features (HBCs) represent a biological spectrum of aggressive neoplasms in children and young adults

Sumazin, P.; Lopez-Terrada, D.

10.1101/2021.07.15.445600 — cancer biology — Posted on 2021-07-16

1910 A new pipeline for the normalization and pooling of metabolomics data

Viallon, V.; His, M.; Rinaldi, S.; Breeur, M.; Gicquiau, A.; Hemon, B.; Overvad, K.; Tjonneland, A.; Rostgaard-Hansen, A. L.; Rothwell, J. A.; Lecuyer, L.; Severi, G.; Kaaks, R.; Johnson, T.; Schulze, M. B.; Palli, D.; Agnoli, C.; Panico, S.; Tumino, R.; Ricceri, F.; Verschuren, M.; Engelfriet, P.; Onland, C.; Vermeulen, R.; Nost, T. H.; Urbarova, I.; Zamora-Ros, R.; Rodriguez-Barranco, M.; Amiano, P.; Huerta, J. M.; Ardanaz, E.; Melander, O.; Ottoson, F.; Vidman, L.; Rentoft, M.; Schmidt, J. A.; Travis, R. C.; Weiderpass, E.; Johansson, M.; Dossus, L.; Jenab, M.; Gunter, M. J.; Bermejo, L.; S

10.1101/2021.07.16.452593 — bioinformatics — Posted on 2021-07-16

1911 Structural basis for protein glutamylation by the Legionella pseudokinase SidJ

Adams, M.; Sharma, R.; Colby, T.; Weis, F.; Matic, I.; Bhogaraju, S.

10.1101/2021.07.16.451782 — biochemistry — Posted on 2021-07-16

1912 Social niche construction in captive Gouldian Finch (Erythrura gouldiae) Flocks

Kohn, G. M.; Nugent, M. R.; Dail, X.; Orlandi, T. R.

10.1101/2021.07.16.452682 — animal behavior and cognition — Posted on 2021-07-16

1913 Transposable element activity in the transcriptomic analysis of mouse pancreatic tumors

Lerat, E.; Burlet, N.; Navratil, V.; Nous, C.

10.1101/2021.07.16.452652 — genomics — Posted on 2021-07-16

1914 Detailed phylogeographic analysis of sticklebacks exposes challenges in genetic studies of admixed populations

Feng, X.; Merila, J.; Loytynoja, A.

10.1101/2021.07.16.452636 — genomics — Posted on 2021-07-16

1915 A synthetic lethal screen identifies HDAC4 as a potential target in MELK overexpressing cancers

Foijer, F.; Zhou, L.; Rosas Bringas, F. R.; Bakker, B.; Simon, J. E.; Bakker, P. L.; Kazemier, H. G.; Schubert, M.; Roorda, M.; van Vugt, M.; Chang, M.

10.1101/2021.07.16.452653 — genetics — Posted on 2021-07-16

1916 Emergent evolutionary forces in spatial models of luminal growth in the human gut microbiota

Ghosh, O. M.; Good, B. H.

10.1101/2021.07.15.452569 — evolutionary biology — Posted on 2021-07-16

1917 Modeling lung cell development using human pluripotent stem cells

Ngan, Z.; Quach, H.; Dierolf, J.; Lee, J.-A.; Huang, E. N.; Wong, A. P.

10.1101/2021.07.16.452691 — developmental biology — Posted on 2021-07-16

1918 LGR6 is necessary for attaining peak bone mass and regulates osteogenesis through differential ligand use

Khedgikar, V.; Charles, J. F.; Lehoczky, J. A.

10.1101/2021.07.16.452698 — developmental biology — Posted on 2021-07-16

1919 Abnormal triaging of misfolded proteins by adult neuronal ceroid lipofuscinosis-associated CSPα mutants causes lipofuscin accumulation

Ye, Y.; Lee, J.; Xu, Y.; Saidi, L.; Xu, M.; Zinsmaier, K.

10.1101/2021.07.16.452648 — cell biology — Posted on 2021-07-16

1920 Low dose AKT inhibitor miransertib cures PI3K-related vascular malformations in preclinical models of human disease

Kobialka, P.; Sabata, H.; Vilalta, O.; Angulo-Urarte, A.; Muixi, L.; Zanoncello, J.; Munoz-Aznar, O.; Olaciregui, N. G.; Lavarino, C.; Celis, V.; Rovira, C.; Lopez-Fernandez, S.; Baselga, E.; Mora, J.; Castillo, S. D.; Graupera, M.

10.1101/2021.07.16.452617 — molecular biology — Posted on 2021-07-16

1921 Global and Gene-specific Transcriptional Responses to Acute Stress

Fischl, H. J.; Brown, T.; Angel, A.; Mellor, J.

10.1101/2021.07.16.452657 — molecular biology — Posted on 2021-07-16

1922 Histone H3 deacetylation promotes host cell viability for efficient infection by Listeria monocytogenes

Eldridge, M. J. G.; Hamon, M. A.

10.1101/2021.07.16.452630 — molecular biology — Posted on 2021-07-16

1923 Spontaneous Mutants of Streptococcus sanguinis with Defects in the Glucose-PTS Show Enhanced Post-Exponential Phase Fitness

Zeng, L.; Walker, A. R.; Lee, K.; Taylor, Z. A.; Burne, R. A.

10.1101/2021.07.15.452590 — microbiology — Posted on 2021-07-16

1924 Neutralization of recombinant RBD-subunit vaccine ZF2001-elicited antisera to SARS-CoV-2 variants including Delta

Zhao, X.; Zheng, A.; Li, D.; Zhang, R.; Sun, H.; Wang, Q.; Gao, G. F.; Han, P.; Dai, L.

10.1101/2021.07.15.452504 — immunology — Posted on 2021-07-16

1925 A single de novo substitution in SARS-CoV-2 spike informs enhanced adherence to human ACE2.

Erausquin, E.; Lopez-Sagaseta, J.

10.1101/2021.07.16.452441 — immunology — Posted on 2021-07-16

1926 The gut microbiota of environmentally enriched mice regulates visual cortical plasticity

Lupori, L.; Cornuti, S.; Mazziotti, R. M.; Borghi, E.; Ottaviano, E.; Sagona, G.; Pizzorusso, T.; Tognini, P.

10.1101/2021.07.16.452307 — neuroscience — Posted on 2021-07-16

1927 Lower cognitive set shifting ability is associated with stiffer balance recovery behavior and larger perturbation-evoked cortical responses in older adults

Payne, A.; Palmer, J. A.; McKay, J. L.; Ting, L. H.

10.1101/2021.07.16.452646 — neuroscience — Posted on 2021-07-16

1928 Repetition effects in action selection reflect effector- but not hemisphere-specific coding

Seegelke, C.; Schonard, C.; Heed, T.

10.1101/2021.07.16.450393 — neuroscience — Posted on 2021-07-16

1929 Left-handedness and its genetic influences are associated with structural asymmetries mapped across the cerebral cortex in 31,864 individuals

Sha, Z.; Pepe, A.; Schijven, D.; Carrion Castillo, A.; Roe, J. M.; Westerhausen, R.; Joliot, M.; Fisher, S. E.; Crivello, F.; Francks, C.

10.1101/2021.07.16.452594 — neuroscience — Posted on 2021-07-16

1930 From computing transition probabilities to word recognition in sleeping neonates, a two-step neural tale

Flo, A.; Benjamin, L.; Palu, M.; Dehaene-Lambertz, G.

10.1101/2021.07.16.452631 — neuroscience — Posted on 2021-07-16

1931 The context of experienced sensory discrepancies shapes multisensory integration and recalibration differently

Park, H.; Kayser, C.

10.1101/2021.07.16.452674 — neuroscience — Posted on 2021-07-16

1932 Cellular signaling beyond the Wiener-Kolmogorov limit

Weisenberger, C.; Hathcock, D.; Hinczewski, M.

10.1101/2021.07.15.452575 — systems biology — Posted on 2021-07-16

1933 Abortion occurs during double fertilisation and ovule development in Paeonia ludlowii

Chen, T.; Xie, M.; Jiang, Y.; Yuan, T.

10.1101/2021.07.16.452677 — plant biology — Posted on 2021-07-16

1934 Genome-wide characterization of the MLO gene family in Cannabis sativa reveals two genes as strong candidates for powdery mildew susceptibility

Pepin, N.; Hebert, F. O.; Joly, D. L.

10.1101/2021.07.16.452661 — plant biology — Posted on 2021-07-16

1935 Sustainable use of plant protection products in heroic viticulture areas.Reducing risks to the environment and winemaking.

Cortinas Rodriguez, J. A.; Fernandez-Conde, M. E.

10.1101/2021.07.16.452637 — pathology — Posted on 2021-07-16

1936 Generating and testing hypotheses about the fossil record of insect herbivory with a theoretical ecospace

Schachat, S. R.; Payne, J. L.; Boyce, C. K.; Labandeira, C. C.

10.1101/2021.07.16.452692 — paleontology — Posted on 2021-07-16

1937 DNA methylation cues in nucleosome geometry, stability, and unwrapping

Li, S.; Peng, Y.; Landsman, D.; Panchenko, A.

10.1101/2021.07.16.452533 — biophysics — Posted on 2021-07-16

1938 Temperature and Guanidine Hydrochloride effects on the folding thermodynamics of WW domain and variants

Qin, M.; Liu, Z.; Wang, W.; Thirumalai, D.

10.1101/2021.07.16.452632 — biophysics — Posted on 2021-07-16

1939 Structure of the Infective Getah Virus at 2.8 A-resolution Determined by Cryo-electron Microscopy

Wang, A.; Zhou, F.; Liu, C.; Gao, D.; Qi, R.; Liu, S.; Xia, Y.; Wang, C.; Liu, Z.

10.1101/2021.07.16.452580 — biophysics — Posted on 2021-07-16

1940 Quantifying and correcting slide-to-slide variation in multiplexed immunofluorescence images

Harris, C. R.; McKinley, E. T.; Roland, J. T.; Liu, Q.; Shrubsole, M. J.; Lau, K.; Coffey, R. J.; Wrobel, J.; Vandekar, S.

10.1101/2021.07.16.452359 — bioinformatics — Posted on 2021-07-16

1941 Promotech: A general tool for bacterial promoter recognition

Chevez-Guardado, R.; Pena-Castillo, L.

10.1101/2021.07.16.452684 — bioinformatics — Posted on 2021-07-16

1942 Functional analyses of phosphatidylserine/PI(4)P exchangers with diverse lipid species and membrane contexts set unanticipated rules on lipid transfer

Ikhlef, S.; Lipp, N.-F.; Delfosse, V.; Fuggetta, N.; Bourguet, W.; Magdeleine, M.; Drin, G.

10.1101/2021.07.16.452025 — biochemistry — Posted on 2021-07-16

1943 Membrane thickness, lipid phase and sterol type are determining factors in the permeability of membranes to small solutes

Frallicciardi, J.; Melcr, J.; Siginou, P.; Marrink, S. J.; Poolman, B.

10.1101/2021.07.16.452599 — biochemistry — Posted on 2021-07-16

1944 Active inference through whiskers

Mannella, F.; Maggiore, F.; Baltieri, M.; Pezzulo, G.

10.1101/2021.07.16.452665 — animal behavior and cognition — Posted on 2021-07-16

1945 Network-based pathogenicity prediction for variants of uncertain significance

Kamada, M.; Takagi, A.; Kojima, R.; Tanaka, Y.; Nakatsui, M.; Tanabe, N.; Hirata, M.; Yoshida, T.; Okuno, Y.

10.1101/2021.07.15.452566 — genomics — Posted on 2021-07-16

1946 Phylogenetic profiling suggests early origin of the core subunits of Polycomb Repressive Complex 2 (PRC2)

Sharaf, A.; Vijayanathan, M.; Obornik, M.; Mozgova, i.

10.1101/2021.07.16.452543 — evolutionary biology — Posted on 2021-07-16

1947 Innate immune pathways act synergistically to constrain RNA virus evolution in Drosophila melanogaster

Mongelli, V.; Lequime, S.; Kousathanas, A.; Gausson, V.; Blanc, H.; Quintana-Murci, L.; Elena, S. F.; Saleh, M.-C.

10.1101/2021.07.16.452470 — evolutionary biology — Posted on 2021-07-16

1948 Multiple parasitoid species enhance top-down control, but parasitoid performance is context-dependent

Thierry, M.; Pardikes, N. A.; Ximenez-Embrun, M. G.; Proudhom, G.; Hrcek, J.

10.1101/2021.07.16.452484 — ecology — Posted on 2021-07-16

1949 TGF-β modulates cell fate in human ES cell-derived foregut endoderm by inhibiting multiple endogenous signaling pathways

Funa, N. S.; de Lichtenberg, K. H.; Hansen, M. S.; Kuylenstierna, J. v. C.; Jensen, K. B.; Miao, Y.; Garcia, K. C.; Serup, P.

10.1101/2021.07.15.452587 — developmental biology — Posted on 2021-07-16

1950 The molecular architecture of vimentin filaments

Eibauer, M.; Weber, M. S.; Turgay, Y.; Sivagurunathan, S.; Goldman, R. D.; Medalia, O.

10.1101/2021.07.15.452584 — cell biology — Posted on 2021-07-16

1951 The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin

Krastev, D. B.; Li, S.; Sun, Y.; Wicks, A.; Weekes, D.; Badder, L. M.; Knight, E. G.; Marlow, R.; Pardo Calvo, M.; Yu, L.; Talele, T. T.; Bartek, J.; Choudhary, J.; Pommier, Y.; Pettitt, S. J.; Tutt, A.; Ramadan, K.; Lord, C. J.

10.1101/2021.07.16.452473 — molecular biology — Posted on 2021-07-16

1952 An oligosaccharide analog exhibited antifungal activity by misleading cell wall organization via targeting PHR transglucosidases

Li, R.; Wang, Z.; Zhu, L.; Liu, D.; Wang, W.; Zhang, C.; Jiao, S.; Wei, J.; Ren, L.; Zhang, Y.; Gou, X.; Yuan, X.; Du, Y.

10.1101/2021.07.16.452596 — microbiology — Posted on 2021-07-16

1953 The tetrameric assembly of 2-aminomuconic acid dehydrogenase is a functional requirement of cofactor NAD+ binding

Shi, Q.; Chen, Y.; Li, X.; Dong, H.; Chen, C.; Zhong, Z.; Yang, C.; Liu, G.; Su, D.

10.1101/2021.07.15.452591 — microbiology — Posted on 2021-07-16

1954 Collaboration Between Host and Viral Factors Shape SARS-CoV-2 Evolution

Bamford, C. G. G.; Broadbent, L.; Aranday Cortes, E.; McCabe, M.; McKenna, J.; Courtney, D.; Touzelet, O.; Ali, A.; Roberts, G.; Lopez Campos, G.; Simpson, D.; McCaughey, C.; Fairley, D.; Mills, K.; Power, U. F.; The Breathing Together Consortium,

10.1101/2021.07.16.452629 — microbiology — Posted on 2021-07-16

1955 BET protein inhibition regulates macrophage chromatin accessibility and microbiota-dependent colitis

Hoffner O'Connor, M.; Berglind, A.; Kennedy, M. M.; Keith, B. P.; Lynch, Z. J.; Schaner, M. R.; Steinbach, E. C.; Herzog, J.; Trad, O. K.; Jeck, W. R.; Arthur, J. C.; Sartor, R. B.; Furey, T.; Sheikh, S. Z.

10.1101/2021.07.15.452570 — immunology — Posted on 2021-07-16

1956 Epigenetic modulation of selected immune response genes and altered functions of T lymphocytes and macrophages collectively contribute to autoimmune diabetes protection

Jayaraman, S.; Arianas, M.; Jayaraman, A.

10.1101/2021.07.15.452572 — immunology — Posted on 2021-07-16

1957 Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection

Sasaki, Y.; Zhu, J.; Shi, Y.; Gu, W.; Kobe, B.; Ve, T.; DiAntonio, A.; Milbrandt, J.

10.1101/2021.07.15.452560 — neuroscience — Posted on 2021-07-16

1958 BAI-Net: Individualized Human Cerebral Cartography using Graph Convolutional Network

Ma, L.; Zhang, Y.; Zhang, H.; Cheng, L.; Zhuo, J.; Shi, W.; Lu, Y.; Li, W.; Wang, J.; Yang, Z.; Fan, L.; Jiang, T.

10.1101/2021.07.15.452577 — neuroscience — Posted on 2021-07-16

1959 Structural connectivity-based segmentation of the human entorhinal cortex

Syversen, I. F.; Witter, M. P.; Kobro-Flatmoen, A.; Goa, P. E.; Navarro Schröder, T.; Doeller, C. F.

10.1101/2021.07.16.452500 — neuroscience — Posted on 2021-07-16

1960 Dynamic variations of resting-state BOLD signal spectra in white matter

Li, M.; Gao, Y.; Anderson, A. W.; Ding, Z.; Gore, J. C.

10.1101/2021.07.15.452567 — neuroscience — Posted on 2021-07-16

1961 Antipsychotic-induced epigenomic reorganization in frontal cortex samples from individuals with schizophrenia

Zhu, B.; Ainsworth, R. I.; Wang, Z.; Sierra, S.; Deng, C.; Callado, L. F.; Meana, J. J.; Wang, W.; Lu, C.; Gonzalez-Maeso, J.

10.1101/2021.07.14.452426 — neuroscience — Posted on 2021-07-16

1962 Diversified physiological sensory input connectivity questions the existence of distinct classes of spinal interneurons in the adult cat in vivo

Kohler, M.; Bengtsson, F.; Stratmann, P.; Roehrbein, F.; Knoll, A.; Albu-Schaeffer, A.; Joerntell, H.

10.1101/2021.07.16.452238 — neuroscience — Posted on 2021-07-16

1963 Climatic niche pre-adaptation in mainland Europe facilitated the colonization of Madeira by ivies (Hedera L., Araliaceae)

Alonso, A.; Gallego-Narbon, A.; Coca-de-la-Iglesia, M.; Monjas, D.; G. Medina, N.; Fernandez-Mazuecos, M.; Valcarcel, V.

10.1101/2021.07.16.452604 — plant biology — Posted on 2021-07-16

1964 A completely parameter-free method for graph-based single cell RNA-seq clustering

Zand, M.; Ruan, J.

10.1101/2021.07.15.452521 — bioinformatics — Posted on 2021-07-16

1965 Accurate prediction of functional states of cis-regulatory modules reveals the universal epigenetic code in mammals

Ni, P.; Su, Z.

10.1101/2021.07.15.452574 — bioinformatics — Posted on 2021-07-16

1966 On the Apportionment of Archaic Human Diversity

Villanea, F. A.; Witt, K. E.; Loughran, E.; Huerta-Sanchez, E. A.

10.1101/2021.07.15.452563 — genomics — Posted on 2021-07-16

1967 Engineering functional human gastrointestinal organoid tissues using the three primary germ layers separately derived from pluripotent stem cells

Eicher, A. K.; Kechele, D. O.; Sundaram, N.; Berns, H. M.; Poling, H. M.; Haines, L. E.; Sanchez, J. G.; Kishimoto, K.; Krishnamurthy, M.; Han, L.; Zorn, A. M.; Helmrath, M. A.; Wells, J. M.

10.1101/2021.07.15.452523 — developmental biology — Posted on 2021-07-16

1968 Latent neural dynamics encode temporal context in speech

Stephen, E. P.; Li, Y.; Metzger, S.; Oganian, Y.; Chang, E. F.

10.1101/2021.07.15.452519 — neuroscience — Posted on 2021-07-16

1969 Gambling environment exposure increases temporal discounting but improves model-based control in regular slot-machine gamblers.

Wagner, B. J.; Mathar, D.; Peters, J.

10.1101/2021.07.15.452520 — neuroscience — Posted on 2021-07-16

1970 Experience-Driven Rate Modulation is Reinstated During Hippocampal Replay

Tirole, M.; Huelin Gorriz, M.; Takigawa, M.; Kukovska, L.; Bendor, D.

10.1101/2021.07.15.452506 — neuroscience — Posted on 2021-07-16

1971 Time cell encoding in deep reinforcement learning agents depends on mnemonic demands

Lin, D.; Richards, B. A.

10.1101/2021.07.15.452557 — neuroscience — Posted on 2021-07-16

1972 Hyperbolic trade-off: the importance of balancing trial and subject sample sizes in neuroimaging

Chen, G.; Pine, D. S.; Brotman, M. A.; Smith, A. R.; Cox, R. W.; Taylor, P. A.; Haller, S. P.

10.1101/2021.07.15.452548 — neuroscience — Posted on 2021-07-16

1973 GuPPy, a Python toolbox for the analysis of fiber photometry data

Sherathiya, V. N.; Schaid, M. D.; Seiler, J. L.; Lopez, G. C.; Lerner, T.

10.1101/2021.07.15.452555 — neuroscience — Posted on 2021-07-16

1974 Identification of G Protein αi Signaling Partners by Proximity Labeling Reveals a Network of Interactions that Includes PDZ-RhoGEF

Chandan, N. R.; Abraham, S.; SenGupta, S.; Parent, C. A.; Smrcka, A. V.

10.1101/2021.07.15.452545 — pharmacology and toxicology — Posted on 2021-07-16

1975 The role of the first transmembrane helix in bacterial YidC: Insights from the crystal structure and molecular dynamics simulations

Li, X.; Nass, K. J.; Ilie, I. M.; Saller, M. J.; Driessen, A. J. M.; Caflisch, A.; Kammerer, R. A.

10.1101/2021.07.15.452481 — biophysics — Posted on 2021-07-16

1976 NOBIAS: Analyzing anomalous diffusion in single-molecule tracks with nonparametric Bayesian inference

Chen, Z.; Geffroy, L.; Biteen, J. S.

10.1101/2021.07.15.452497 — biophysics — Posted on 2021-07-16

1977 Modeling transcriptional profiles of gene perturbation with deep neural network

Liu, W.; Wang, X.; Mani, D. R.; Fenyo, D.

10.1101/2021.07.15.452534 — bioinformatics — Posted on 2021-07-16

1978 Effect of the Ecological Location of a Water Source on Entropy and other Spatio-temporal Behavioral Features: An extended and systematic replication

Hernandez-Eslava, V.; Leon, A.; Guzman, I.; Diaz, F.; Avendano-Garrido, M. L.; Toledo, P.; Hernandez-Linares, C. A.; Luna, I.

10.1101/2021.07.15.452514 — animal behavior and cognition — Posted on 2021-07-16

1979 A genome-wide CRISPR/Cas9 knock-out screen identifies the DEAD box RNA helicase DDX42 as a broad antiviral inhibitor

Bonaventure, B.; Rebendenne, A.; Garcia de Gracia, F.; McKellar, J.; Gracias, S.; Labaronne, E.; Tauziet, M.; Chaves Valadao, A. L.; Bernard, E.; Briant, L.; Gros, N.; Djilli, W.; Arnaud-Arnould, M.; Courgnaud, V.; Parrinello, H.; Rialle, S.; Schulz, R.; Ricci, E. P.; Jouvenet, N.; Moncorge, O.; Goujon, C.

10.1101/2020.10.28.359356 — microbiology — Posted on 2021-07-16

1980 Mapping inter-individual functional connectivity variability in TMS targets for major depressive disorder

Harita, S.; Momi, D.; Mazza, F.; Griffiths, J. D.

10.1101/2021.07.15.452518 — neuroscience — Posted on 2021-07-16

1981 SARS-CoV-2 B.1.617.2 Delta variant emergence, replication and immune evasion

Mlcochova, P.; Kemp, S. A.; Shanker Dhar, M.; Papa, G.; Meng, B.; Mishra, S.; Whittaker, C.; Mellan, T.; Ferreira, I.; Datir, R.; Collier, D.; Singh, S.; Pandey, R.; Ponnusamy, K.; Radhakrishnan, V. S.; Sengupta, S.; Brown, J.; Marwal, R.; Ponnusamy, K.; Radhakrishnan, V. S.; Goonawardne, N.; Abdullahi, A.; Devi, P.; Wattal, C.; Caputo, D.; Peacock, T.; Goel, N.; Vaishya, R.; Charles, O.; Chattopadhyay, P.; Agarwal, M.; Satwik, A.; INSACOG CONSORTIUM, ; NIHR Bioresource Collaboration, ; Mavousian, A.; Brown, J.; Zhou, J.; Goonawardne, N.; Hyeon Lee, J.; Bassi, J.; Silacci-Fegni, C.; Saliba,

10.1101/2021.05.08.443253 — microbiology — Posted on 2021-07-16

1982 Comprehensive taxon sampling and vetted fossils help clarify the time tree of shorebirds (Aves, Charadriiformes)

Cerny, D.; Natale, R.

10.1101/2021.07.15.452585 — evolutionary biology — Posted on 2021-07-16

1983 Theta activity paradoxically boosts gamma and ripple frequency sensitivity in prefrontal interneurons

Merino, R. M.; Leon-Pinzon, C.; Stuehmer, W.; Moeck, M.; Staiger, J. F.; Wolf, F.; Neef, A.

10.1101/2019.12.19.882639 — neuroscience — Posted on 2021-07-16

1984 Probing remdesivir nucleotide analogue insertion to SARS-CoV-2 RNA dependent RNA polymerase in viral replication

Romero, M. E.; Long, C.; La Rocco, D.; Keerthi, A. M.; Xu, D.; Yu, J.

10.1101/2021.07.12.452099 — biophysics — Posted on 2021-07-16

1985 Encoding time in neural dynamic regimes with distinct computational tradeoffs

Zhou, S.; Masmanidis, S. C.; Buonomano, D. V.

10.1101/2021.07.15.452447 — neuroscience — Posted on 2021-07-16

1986 Exploring the tymovirids landscape through metatranscriptomics data

Bejerman, N.; Debat, H.

10.1101/2021.07.15.452586 — microbiology — Posted on 2021-07-16

1987 DTI-Voodoo: machine learning over interaction networks and ontology-based background knowledge predicts drug-target interactions

Hinnerichs, T.; Hoehndorf, R.

10.1101/2021.04.28.441733 — bioinformatics — Posted on 2021-07-16

1988 Plasmin-mediated cleavage of EphA4 at central amygdala inhibitory synapses controls anxiety

Mucha, M.; Labrador-Ramos, A.; Attwood, B.; Bajor, M.; Kolenchery, J.; Skrzypiec, A.; Brambilla, V.; Magnowska, M.; Figiel, I.; Swiatek, M.; Wiktorowska, L.; Shah, R. S.; Pijet, B.; Sakai, Y.; Nagai, N.; Klejman, A.; Wlodarczyk, J.; Kaczmarek, L.; Przewlocki, R.; Pawlak, R.

10.1101/2021.07.16.452595 — neuroscience — Posted on 2021-07-16

1989 Impulsivity and risk-seeking as Bayesian inference under dopaminergic control

Mikhael, J. G.; Gershman, S. J.

10.1101/2020.10.06.327775 — neuroscience — Posted on 2021-07-16

1990 Domain-general conflict monitoring predicts neural and behavioral indices of linguistic error processing during reading comprehension

Brothers, T.; Zeitlin, M.; Choi Perrachione, A.; Choi, C.; Kuperberg, G.

10.1101/2021.01.06.425590 — neuroscience — Posted on 2021-07-16

1991 SMC complexes can traverse physical roadblocks bigger than their ring size

Pradhan, B.; Barth, R.; Kim, E.; Davidson, I. F.; Bauer, B.; van Laar, T.; Yang, W.; Ryu, J.-K.; van der Torre, J.; Peters, J.-M.; Dekker, C.

10.1101/2021.07.15.452501 — biophysics — Posted on 2021-07-16

1992 A Gradient-based Spectral Explainability Method for EEG Deep Learning Classifiers

Ellis, C. A.; Sendi, M. S. E.; Miller, R. L.; Calhoun, V. D.

10.1101/2021.07.14.452360 — bioinformatics — Posted on 2021-07-15

1993 Allele-resolved single-cell multi-omics uncovers the dynamics and transcriptional kinetics of X-chromosome upregulation

Lentini, A.; Cheng, H.; Noble, J.; Papanicolaou, N.; Coucoravas, C.; Andrews, N.; Deng, Q.; Enge, M.; Reinius, B.

10.1101/2021.07.14.452323 — genomics — Posted on 2021-07-15

1994 The myopathic transcription factor DUX4 induces the production of truncated RNA-bindingproteins in human muscle cells

Campbell, A. E.; Dyle, M. C.; Calviello, L.; Matheny, T.; Cortazar, M. A.; Forman, T.; Fu, R.; Gillen, A. E.; Floor, S. N.; Jagannathan, S.

10.1101/2021.06.28.450189 — genomics — Posted on 2021-07-16

1995 Active enhancers strengthen TAD insulation by bRNA mediated CTCF enrichment at the TAD boundaries

Islam, Z.; Saravanan, B.; Walavalkar, K.; Farooq, U.; Singh, A. K.; Thakur, J.; Pandit, A.; Sabarinathan, R.; Henikoff, S.; Notani, D.

10.1101/2021.07.13.452118 — genomics — Posted on 2021-07-16

1996 An Evolutionary Process Without Variation and Selection

Gabora, L.; Steel, M.

10.1101/2020.08.30.274407 — evolutionary biology — Posted on 2021-07-15

1997 Cylcop: An R Package for Circular-Linear Copulae with Angular Symmetry

Hodel, F. H.; Fieberg, J. R.

10.1101/2021.07.14.452253 — ecology — Posted on 2021-07-15

1998 Actin force generation in vesicle formation: mechanistic insights from cryo-electron tomography

Serwas, D.; Akamatsu, M.; Moayed, A.; Vegesna, K.; Vasan, R.; Hill, J. M.; Schoeneberg, J.; Davies, K. M.; Rangamani, P.; Drubin, D. G.

10.1101/2021.06.28.450262 — cell biology — Posted on 2021-07-15

1999 Differential effects of early or late exposure to prenatal maternal immune activation on mouse embryonic neurodevelopment

Guma, E.; Bordeleau, M.; Snook, E.; Desrosiers-Gregoire, G.; Gonzalez Ibanez, F.; Picard, K.; Spring, S.; Lerch, J. P.; Nieman, B. J.; Devenyi, G. A.; Tremblay, M.-E.; Chakravarty, M. M.

10.1101/2021.07.14.452084 — neuroscience — Posted on 2021-07-15

2000 First Report of Lactoria cornuta from Karnataka, West coast of India, Role of tropical cyclones in Range Extension

Navalgund, D. M. Z. I. A.; Mali, G.; Dollin, R.

10.1101/2021.06.28.450260 — zoology — Posted on 2021-07-15

2001 BitEpi: A Fast and Accurate Exhaustive Higher-Order Epistasis Search

Bayat, A.; Hosking, B.; Jain, Y.; Hosking, C.; Kodikara, M.; Reti, D.; Twine, N.; C. Bauer, D.

10.1101/858282 — bioinformatics — Posted on 2021-07-15

2002 Limitations of lymphoblastoid cell lines for establishing genetic reference datasets in the immunoglobulin loci

Rodriguez, O. L.; Sharp, A. J.; Watson, C. T.

10.1101/2021.07.15.452448 — genomics — Posted on 2021-07-15

2003 Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits - the Hispanic/Latino Anthropometry Consortium

Fernandez-Rhodes, L.; Graff, M.; Buchanan, V. L.; Justice, A. E.; Highland, H. M.; Guo, X.; Young, K. L.; Adhikari, K.; Allred, N. P.; Below, J. E.; Bradfield, J.; Pereira, A. C.; Glover, L.; Kim, D.; Lilly, A. G.; Shrestha, P.; Thomas, A. G.; Zhang, X.; Chen, M.; Chiang, C.; Pulit, S.; Horimoto, A.; Krieger, J. E.; Guindo-Martinez, M.; Preuss, M.; Schumann, C.; Smit, R. A. J.; Torres-Mejia, G.; Acuna-Alonzo, V.; Bedoya, G.; Bortolini, M.-C.; Canizales-Quinteros, S.; Gallo, C.; Gonzalez-Jose, R.; Poletti, G.; Rothhammer, F.; Hakonarson, H.; Adler, S. G.; Igo, R.; Iyengar, S.; Nicholas, S. B.;

10.1101/2021.05.27.445969 — genetics — Posted on 2021-07-15

2004 Non-invasive imaging of gene expression and protein secretion dynamics in living mice

Nourse, J.; Tokalov, S.; Khokhar, S.; Khan, E.; Schott, L. K.; Hinz, L.; Eder, L.; Arnold-Schild, D.; Probst, H. C.; Danckwardt, S.

10.1101/2021.07.08.451623 — genetics — Posted on 2021-07-15

2005 Quantifying the impact of data sharing on variant classification

Casaletto, J.; Cline, M.; Shirts, B. H.

10.1101/2021.06.21.449318 — genetics — Posted on 2021-07-15

2006 The haplotype-based analysis of Aegilops tauschii introgression into hard red winter wheat and its impact on productivity traits

Nyine, M.; Adhikari, E.; Clinesmith, M.; Aiken, R.; Betzen, B.; wang, w.; Davidson, D.; Yu, Z.; Guo, Y.; He, F.; Akhunov, A.; Jordan, K. W.; Fritz, A. K.; Akhunov, E.

10.1101/2021.05.29.446303 — genetics — Posted on 2021-07-15

2007 Mmp-13 deletion in cells of the mesenchymal lineage increases bone mass, decreases endocortical osteoclast number, and attenuates the cortical bone loss caused by estrogen deficiency in mice

Ponte, F.; Kim, H.-N.; Warren, A.; Iyer, S.; Han, L.; Mannen, E.; Gomez-Acevedo, H.; Nookaew, I.; Almeida, M.; Manolagas, S. C.

10.1101/2021.07.15.452452 — molecular biology — Posted on 2021-07-15

2008 Heterogeneity in the transcriptional response of the human pathogen Aspergillus fumigatus to the antifungal agent caspofungin

Colabardini, A. C.; Wang, F.; Dong, Z.; Pardeshi, L.; Rocha, M. C.; Costa, J. H.; dos Reis, T. F.; Brown, A.; Jaber, Q. Z.; Fridman, M.; Fill, T.; Rokas, A.; Malavazi, I.; Wong, K. H.; Goldman, G. H.

10.1101/2021.07.15.452449 — microbiology — Posted on 2021-07-15

2009 Inactivation effects of plasma-activated water on Fusarium graminearum

Guo, J.; Wang, J.; Xie, H.; Jiang, J.; Li, C.; Li, W.; Li, L.; Liu, X.; Lin, F.

10.1101/2021.07.15.452455 — microbiology — Posted on 2021-07-15

2010 Hypersensitivity of MAIT cells to Leukocidin ED indicates a Staphylococcus aureus immune evasion mechanism targeting the innate effector cell response

Boulouis, C.; Leeansyah, E.; Shambat, S. M.; Norrby-Teglund, A.; Sandberg, J. K.

10.1101/2021.07.15.452453 — immunology — Posted on 2021-07-15

2011 How Axon and Dendrite Branching Are Governed by Time, Energy, and Spatial Constraints

Desai-Chowdhry, P.; Brummer, A.; Savage, V.

10.1101/2021.07.15.452445 — neuroscience — Posted on 2021-07-15

2012 Exosome TDP-43 profile in canine model of ALS: A preliminary study in developing surrogate biomarker

Pfeiffer, P.; Coates, J. R.; Esqueda, Y. M.; Kennedy, A.; Getchell, K.; McLenon, M.; Kosa, E.; Agbas, A.

10.1101/2021.06.17.448876 — neuroscience — Posted on 2021-07-15

2013 MFmap: A semi-supervised generative model matching cell lines to tumours and cancer subtypes

Kschischo, M.; Zhang, X.

10.1101/2021.07.15.452446 — bioinformatics — Posted on 2021-07-15

2014 Model-based identification of conditionally-essential genes from transposon-insertion sequencing data

Sarsani, V.; Aldikacti, B.; He, S.; Zeinert, R.; Chien, P.; Flaherty, P.

10.1101/2021.07.15.452443 — bioinformatics — Posted on 2021-07-15

2015 Variant calling tool evaluation for variable size indel calling from next generation whole genome and targeted sequencing data

Wang, N.; Lysenkov, V.; Orte, K.; Kairisto, V.; Aakko, J.; Khan, S.; Elo, L. L.

10.1101/2021.07.15.452444 — bioinformatics — Posted on 2021-07-15

2016 c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease

Smith, A. O.; Jonassen, J. A.; Preval, K. M.; Davis, R. J.; Pazour, G. J.

10.1101/2021.07.15.452451 — genetics — Posted on 2021-07-15

2017 Minimizing the ex vivo confounds of cell-isolation techniques on transcriptomic profiles of purified microglia

Ocanas, S. R.; Pham, K. D.; Blankenship, H. E.; Machalinski, A. H.; Chucair-Elliott, A. J.; Freeman, W. M.

10.1101/2021.07.15.452509 — neuroscience — Posted on 2021-07-15

2018 Evolving social behaviour through selection of single-cell adhesion in Dictyostelium discoideum

Adiba, S.; Forget, M.; De Monte, S.

10.1101/2021.07.15.452515 — evolutionary biology — Posted on 2021-07-15

2019 Sampling bias exaggerates a textbook example of a trophic cascade

Brice, E.; Larsen, E.; MacNulty, D.

10.1101/2020.05.05.079459 — ecology — Posted on 2021-07-15

2020 Long distance runners in the marine realm: New insights into genetic diversity, kin relationships and social fidelity of Indian Ocean male sperm whales

Girardet, J.; Sarano, F.; Richard, G.; Tixier, P.; Guinet, C.; Alexander, A.; Sarano, V.; Vitry, H.; Preud'Homme, A.; Heuzey, R.; Garcia-Cegarra, A. M.; Adam, O.; Madon, B.; Jung, J.-L.

10.1101/2021.04.23.440733 — ecology — Posted on 2021-07-15

2021 Fine-scale spatial patterns of wildlife disease are common and understudied

Albery, G. F.; Sweeny, A.; Becker, D.; Bansal, S.

10.1101/2020.09.01.277442 — ecology — Posted on 2021-07-15

2022 CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels

Gonçalves, A. B.; Hasselbalch, S. K.; Joensen, B. B.; Patzke, S.; Martens, P.; Ohlsen, S. K.; Quinodoz, M.; Nikopoulus, K.; Suleiman, R.; Jeppesen, M. P. D.; Weiss, C.; Christensen, S. T.; Rivolta, C.; Andersen, J. S.; Farinelli, P.; Pedersen, L. B.

10.1101/2020.10.05.325936 — cell biology — Posted on 2021-07-15

2023 LincRNA-Cox2 functions to regulate inflammation in alveolar macrophages during acute lung injury.

Robinson, E. K.; Worthington, A. K.; Poscablo, D. M.; Shapleigh, B.; Salih, M. M.; Halasz, H.; Seninge, L.; Mosqueira, B.; Smaliy, V.; Forsberg, E. C.; Carpenter, S.

10.1101/2021.07.15.452529 — immunology — Posted on 2021-07-15

2024 Bilateral alignment of receptive fields in the olfactory cortex

Grimaud, J.; Dorrell, W.; Pehlevan, C. N.; Murthy, V. N.

10.1101/2020.02.24.960922 — neuroscience — Posted on 2021-07-15

2025 Chr21 protein-protein interactions: enrichment in products involved in intellectual disabilities, autism and Late Onset Alzheimer Disease

Viard, J.; Loe-Mie, Y.; Khelfaoui, M.; Daudin, R.; Plancon, C.; Boland, A.; Tejedor, F.; Huganir, R.; Kim, E.; Kinoshita, M.; Liu, G.; Haucke, V.; Moncion, T.; Yu, E.; Hindie, V.; Blehaut, H.; Mircher, C.; Herault, Y.; Deleuze, J.-F.; Rain, J.-C.; Simonneau, M.; Lepagnol-Bestel, A.-M.

10.1101/2019.12.11.872606 — neuroscience — Posted on 2021-07-15

2026 On stability of Canonical Correlation Analysis and Partial Least Squares with application to brain-behavior associations

Helmer, M.; Warrington, S. D.; Mohammadi-Nejad, A.-R.; Ji, J. L.; Howell, A.; Rosand, B.; Anticevic, A.; Sotiropoulos, S. N.; Murray, J. D.

10.1101/2020.08.25.265546 — neuroscience — Posted on 2021-07-15

2027 Temporal Scaling of Human Scalp-Recorded Potentials

Hassall, C. D.; Harley, J.; Kolling, N.; Hunt, L. T.

10.1101/2020.12.11.421180 — neuroscience — Posted on 2021-07-15

2028 GPR39 Localization in Aging Human Brain and Correlation of Expression and Polymorphism with Vascular Cognitive Impairment

Davis, C.; Bah, T.; Zhang, W.; Nelson, J.; Golgotiu, K.; Nie, X.; Alkayed, F.; Young, J.; Woltjer, R.; Silbert, L.; Grafe, M.; Alkayed, N. J.

10.1101/2021.07.15.452525 — neuroscience — Posted on 2021-07-15

2029 Synaptic decline precedes dopaminergic neuronal loss in human midbrain organoids harboring a triplication of the SNCA gene

Modamio, J.; Saraiva, C.; Gomez-Giro, G.; Nickels, S. L.; Jarazo, J.; Antony, P.; Barbuti, P.; Halder, R.; Jaeger, C.; Krueger, R.; Glaab, E.; Schwamborn, J. C.

10.1101/2021.07.15.452499 — neuroscience — Posted on 2021-07-15

2030 Data-independent acquisition protease-multiplexing enables increased proteome sequence coverage across multiple fragmentation modes

Richards, A. L.; Chen, K.-H.; Wilburn, D. B.; Stevenson, E.; Polacco, B.; Searle, B. C.; Swaney, D. L.

10.1101/2021.07.15.452565 — systems biology — Posted on 2021-07-15

2031 A Scalable, Open-Source Implementation of a Large-Scale Mechanistic Model for Single Cell Proliferation and Death Signaling

Erdem, C.; Mutsuddy, A.; Bensman, E. M.; Dodd, W.; Saint-Antoine, M. M.; Bouhaddou, M.; Blake, R. C.; Gross, S. M.; Heiser, L. M.; Feltus, F. A.; Birtwistle, M. R.

10.1101/2020.11.09.373407 — systems biology — Posted on 2021-07-15

2032 Supra-physiological levels of Gibberellins/DELLAs alter the patterning, morphology and abundance of root hairs in root tips of A. thaliana seedlings

McCarthy-Suarez, I.

10.1101/2021.07.15.452505 — plant biology — Posted on 2021-07-15

2033 Decellularized Normal and Tumor Scaffolds for Cancer Organoid Cultures as a Model of Colorectal Peritoneal Metastases

Varinelli, L.; Guaglio, M.; Brich, S.; Zanutto, S.; Belfiore, A.; Zanardi, F.; Iannelli, F.; Oldani, A.; Costa, E.; Chighizola, M.; Minardi, S. P.; Fortuzzi, S.; Filugelli, M.; Garzone, G.; Vecchi, M.; Pruneri, G.; Kusamura, S.; Baratti, D.; Cattaneo, L.; Parazzoli, D.; Podesta, A.; Milione, M.; Deraco, M.; Pierotti, M. A.; Gariboldi, M.

10.1101/2021.07.15.452437 — cancer biology — Posted on 2021-07-15

2034 CHRM1 is a Druggable Melanoma Target Whose Endogenous Activity is Determined by Inherited Genetic Variation in DOPA Production

Doepner, M.; Natale, C. A.; Lee, I. Y.; Venkat, S.; Kim, S. H.; Katzenellenbogen, J. A.; Katzenellenbogen, B. S.; Feigin, M.; Ridky, T. W.

10.1101/2021.03.03.433757 — cancer biology — Posted on 2021-07-15

2035 A structural property for reduction of biochemical networks

Kueken, A.; Wendering, P.; Langary, D.; Nikoloski, Z.

10.1101/2021.03.17.435785 — bioinformatics — Posted on 2021-07-15

2036 Deep Learning Achieves Neuroradiologist-Level Performance in Detecting Hydrocephalus

Huang, Y.; Moreno, R.; Malani, R.; Meng, A.; Swinburne, N.; Holodny, A. I.; Choi, Y.; Parra, L. C.; Young, R. J.

10.1101/2021.01.19.427328 — bioinformatics — Posted on 2021-07-15

2037 Bioinformatic and mechanistic analysis of the palmerolide PKS-NRPS biosynthetic pathway from the microbiome of an Antarctic ascidian

Avalon, N. E.; Murray, A. E.; Daligault, H. E.; Lo, C.-C.; Dichosa, A. E. K.; Davenport, K. W.; Chain, P. S. G.; Baker, B. J.

10.1101/2021.04.05.438531 — biochemistry — Posted on 2021-07-15

2038 A coordinated function of lncRNA HOTTIP and miRNA-196b underpinning leukemogenesis by targeting Fas signaling

Singh, A.; Luo, H.; Matur, M.; Eshelman, M.; Sharma, A.; Huang, S.

10.1101/2021.07.15.452559 — biochemistry — Posted on 2021-07-15

2039 Comparative Genome Analysis Reveals Human Pathogenic Potential of ESBL-Escherichia coli Isolated from Swine Microbiomes

Founou, L. L.; Founou, R. C.; Allam, M.; Ismael, A.; Essack, S. Y.

10.1101/2021.07.15.452468 — genomics — Posted on 2021-07-15

2040 Integrated transcriptomics identifies β-cell subpopulations and genetic networks associated with obesity and glycemic control in SM/J mice

Miranda, M. A.; Macias-Velasc, J. F.; Schmidt, H.; Lawson, H. A.

10.1101/2021.07.15.452524 — genomics — Posted on 2021-07-15

2041 Cell-free DNA Profiling Informs Major Complications of Hematopoietic Cell Transplantation

Cheng, A. P.; Cheng, M. P.; Loy, C. J.; Lenz, J. S.; Chen, K.; Smalling, S.; Burnham, P.; Timblin, K. M.; Orejas, J. L.; Silverman, E.; Polak, P.; Marty, F. M.; Ritz, J.; De Vlaminck, I.

10.1101/2020.04.25.061580 — genomics — Posted on 2021-07-15

2042 Illumina iSeq 100 and MiSeq exhibit similar performance in freshwater fish environmental DNA metabarcoding

Nakao, R.; Inui, R.; Akamatsu, Y.; Goto, M.; Matsuoka, S.; Doi, H.

10.1101/2020.08.04.228080 — ecology — Posted on 2021-07-15

2043 Understanding Mechanisms of Chamber-Specific Differentiation Through Combination of Lineage Tracing and Single Cell Transcriptomics

Gonzalez, D. M.; Schrode, N.; Ebrahim, T.; Beaumont, K. G.; Sebra, R.; Dubois, N.

10.1101/2021.07.15.452540 — developmental biology — Posted on 2021-07-15

2044 Nuclear hormone receptors promote gut and glia detoxifying enzyme induction and protect C. elegans from the mold P. brevicompactum

Wallace, S. W.; Lizzappi, M. C.; Hur, H.; Liang, Y.; Shaham, S.

10.1101/2021.07.15.452486 — cell biology — Posted on 2021-07-15

2045 The Mitochondrial Permeability Transition Pore Activates the Mitochondrial Unfolded Protein Response and Promotes Aging

Angeli, S.; Foulger, A.; Chamoli, M.; Peiris, T. H.; Gerencser, A.; Shahmirzadi, A. A.; Andersen, J.; Lithgow, G.

10.1101/2020.11.03.366815 — cell biology — Posted on 2021-07-15

2046 Monitoring the spread of SARS-CoV-2 variants in Moscow and the Moscow region using targeted high-throughput sequencing

Borisova, N. I.; Kotov, I. A.; Kolesnikov, A. A.; Kaptelova, V. V.; Speranskaya, A. S.; Kondrasheva, L. Y.; Tivanova, E. V.; Khafizov, K.; Akimkin, V. G.

10.1101/2021.07.15.452488 — molecular biology — Posted on 2021-07-15

2047 BAZ2A-RNA mediated association with TOP2A and KDM1A represses gene expression in prostate cancer

Roganowicz, M.; Baer, D.; Santoro, R.

10.1101/2021.07.15.452487 — molecular biology — Posted on 2021-07-15

2048 Estradiol-induced progesterone synthesis develops post-puberty in the rostral hypothalamus and coincides with post-pubertal changes in the steroidogenic pathway in female mouse hypothalamic astrocytes

Mohr, M. A.; Keshishian, T.; Falcy, B. A.; Laham, B. J.; Wong, A. M.; Micevych, P. E.

10.1101/833434 — neuroscience — Posted on 2021-07-15

2049 Antagonists targeting eEF2 kinase rescue multiple aspects of pathophysiology in Alzheimer's disease model mice

Kasica, N. P.; Zhou, X.; Wang, X.; Yang, W. P.; Zimmermann, H. R.; Holland, C. E.; Koscielniak, E.; Wu, H.; Cox, A. O.; Lee, J.; Ryazanov, A. G.; Furdui, C. M.; Ma, T.

10.1101/2021.07.15.452522 — neuroscience — Posted on 2021-07-15

2050 Segmenting and Predicting Musical Phrase Structure Exploits Neural Gain Modulation and Phase Precession

Teng, X.; Larrouy-Maestri, P.; Poeppel, D.

10.1101/2021.07.15.452556 — neuroscience — Posted on 2021-07-15

2051 Revealing Protein-Level Functional Redundancy in the Human Gut Microbiome using Ultra-deep Metaproteomics

Li, L.; Ning, Z.; Zhang, X.; Butcher, J.; Simopoulos, C.; Mayne, J. M. A.; Stintzi, A.; Mack, D. R.; Liu, Y.-Y.; Figeys, D.

10.1101/2021.07.15.452564 — systems biology — Posted on 2021-07-15

2052 Ammonium regulates the development and architecture of pine roots through hormonal crosstalk and differential expression of transcription factors in the apex

Ortigosa, F.; Lobato-Fernandez, C.; Shikano, H.; Avila, C.; Taira, S.; Canovas, F. M.; Canas, R. A.

10.1101/2021.07.15.452498 — plant biology — Posted on 2021-07-15

2053 Cellular aging in vitro recapitulates multi-tissue epigenetic aging in vivo

Minteer, C.; Morselli, M.; Meer, M.; Cao, J.; Higgins-Chen, A.; Lang, S.; Pellegrini, M.; Yan, Q.; Levine, M.

10.1101/2020.09.02.280073 — pathology — Posted on 2021-07-15

2054 SARS-Cov-2 Spike binding to ACE2 is stronger and longer ranged with glycans

Huang, Y.; Harris, B. S.; Minami, S. A.; Jung, S.; Shah, P.; Nandi, S.; McDonald, K.; Faller, R.

10.1101/2021.07.15.452507 — biophysics — Posted on 2021-07-15

2055 Rapid plastic shifts in body size precede and determine population growth

Gibert, J. P.; Han, Z.-Y.; Wieczynski, D. J.; Yammine, A.

10.1101/2021.07.15.452551 — ecology — Posted on 2021-07-15

2056 Gut microbiome dysbiosis during COVID-19 is associated with increased risk for bacteremia and microbial translocation.

Venzon, M.; Bernard-Raichon, L.; Klein, J.; Axelrad, J. E.; Hussey, G. A.; Sullivan, A. P.; Cassanovas-Massana, A.; Noval, M. G.; Valero-Jimenez, A. M.; Gago, J.; Wilder, E.; Yale IMPACT Research Team, ; Thorpe, L. E.; Littman, D. R.; Dittmann, M.; Stapleford, K. A.; Shopsin, B.; Torres, V. J.; Ko, A. I.; Iwasaki, A.; Cadwell, K.; Schluter, J.

10.1101/2021.07.15.452246 — microbiology — Posted on 2021-07-15

2057 Supervised generative design of regulatory DNA forgene expression control

Zrimec, J.; Fu, X.; Muhammad, A. S.; Skrekas, C.; Jauniskis, V.; Speicher, N.; Boerlin, C. S.; Verendel, V.; Dubhashi, D.; Chehreghani, M. H.; Siewers, V.; David, F.; Nielsen, J.; Zelezniak, A.

10.1101/2021.07.15.452480 — synthetic biology — Posted on 2021-07-15

2058 Genome-wide analysis of long terminal repeat retrotransposons from the cranberry Vaccinium macrocarpon

Sultana, N.; Menzel, G.; Seibt, K. M.; Garcia, S.; Weber, B.; Serce, S.; Heitkam, T.

10.1101/2021.07.15.452536 — plant biology — Posted on 2021-07-15

2059 Crosstalk between Flavonoids and the Plant Circadian Clock

Hildreth, S. B.; Littleton, E. S.; Clark, L. C.; Puller, G. C.; Kojima, S.; Winkel, B. S. J.

10.1101/2021.07.15.452546 — plant biology — Posted on 2021-07-15

2060 Gut microbiota-based vaccination engages innate immunity to improve blood glucose control in obese mice

Duggan, B. M.; Tamrakar, A. K.; Barra, N. G.; Anhe, F. F.; Paniccia, G.; Wallace, J. G.; Stacey, H. D.; Miller, M. S.; Sloboda, D. M.; Schertzer, J. D.

10.1101/2021.07.15.452537 — physiology — Posted on 2021-07-15

2061 Single-Molecule Manipulation of Macromolecules on Membranes Using High-Resolution Optical Tweezers

Wang, Y.; Jin, H.; Zhang, Y.

10.1101/2021.07.15.452421 — biophysics — Posted on 2021-07-15

2062 Towards a cumulative science of prosody in autism: a cross-linguistic meta-analysis-based investigation of acoustic markers in American and Danish autistic children

Fusaroli, R.; Grossman, R.; Bilenberg, N.; Cantio, C.; Jepsen, J. R. M.; Weed, E.

10.1101/2021.07.13.452165 — bioinformatics — Posted on 2021-07-15

2063 Effects of a 33-sequential beam galactic cosmic ray analog on male mouse behavior and evaluation of CDDO-EA as a radiation countermeasure

Kiffer, F. C.; Luitel, K.; Tran, F. H.; Patel, R. A.; Guzman, C. S.; Soler, I.; Xiao, R.; Shay, J. W.; Yun, S.; Eisch, A. J.

10.1101/2021.07.15.451917 — animal behavior and cognition — Posted on 2021-07-15

2064 Functional and Structural Segregation of Overlapping Helices in HIV-1

Safari, M.; Jayaraman, B.; Yang, S.; Smith, C.; Fernandes, J. D.; Frankel, A. D.

10.1101/2021.07.15.452440 — evolutionary biology — Posted on 2021-07-15

2065 The most comprehensive annotation of the Krill transcriptome provides new insights for the study of physiological processes and environmental adaptation

Urso, I.; Biscontin, A.; Corso, D.; Bertolucci, C.; Romualdi, C.; De Pitta, C.; Meyer, B.; Sales, G.

10.1101/2021.07.15.452476 — ecology — Posted on 2021-07-15

2066 Measuring biodiversity from DNA in the air

Clare, E. L.; Economou, C. K.; Bennett, F. J.; Dyer, C. E.; Adams, K.; McRobie, B.; Drinkwater, R.; Littlefair, J. E.

10.1101/2021.07.15.452392 — ecology — Posted on 2021-07-15

2067 Improving comparability of studies using HCoV-OC43 as a surrogate for SARS-CoV-2

Schirtzinger, E. E.; Kim, Y.; Davis, A. S.

10.1101/2021.07.14.452401 — microbiology — Posted on 2021-07-15

2068 Single cell profiling of T and B cell repertoires following SARS-CoV-2 mRNA vaccine

Sureshchandra, S.; Lewis, S. A.; Doratt, B.; Jankeel, A.; Ibraim, I.; Messaoudi, I.

10.1101/2021.07.14.452381 — immunology — Posted on 2021-07-15

2069 Tuned to Learn: An anticipatory hippocampal convergence state conducive to memory formation revealed during midbrain activation

Poh, J.-H.; Vu, M.-A. T.; Stanek, J. K.; Hsiung, A.; Egner, T.; Adcock, R. A.

10.1101/2021.07.15.452391 — neuroscience — Posted on 2021-07-15

2070 Induced Membrane Curvature Bypasses Clathrin's Essential Endocytic Function

Cail, R. C.; Shirazinejad, C. R.; Drubin, D. G.

10.1101/2021.07.15.452420 — cell biology — Posted on 2021-07-15

2071 Chromatin alterations in the aging lung change progenitor cell activity

Rowbotham, S. P.; Pessina, P.; Garcia de Alba Rivas, C.; Li, J.; Wong, I.; Yoon, J.; Fahey, C.; Moye, A.; Chongsaritsinsuk, J.; Bronson, R.; Ho Sui, S. J.; Kim, C. F.

10.1101/2021.07.15.452072 — molecular biology — Posted on 2021-07-15

2072 Novel municipal sewage-associated bacterial genomes and their potential in source tracking

Lindner, B. G.; Suttner, B.; Conrad, R. E.; Rodriguez-R, L. M.; Hatt, J. K.; Zhu, K. J.; Brown, J.; Konstantinidis, K. T.

10.1101/2021.07.15.452399 — microbiology — Posted on 2021-07-15

2073 Plumage balances camouflage and thermoregulation in Horned Larks (Eremophila alpestris)

Mason, N. A.; Riddell, E.; Romero, F.; Cicero, C.; Bowie, R. C. K.

10.1101/2021.07.15.452373 — zoology — Posted on 2021-07-15

2074 Mining bacterial NGS data vastly expands the complete genomes of temperate phages

Zhang, X.; Wang, R.; Xie, X.; Hu, Y.; Wang, J.; Sun, Q.; Feng, X.; Tong, S.; Cui, Y.; Wang, M.; Zhai, S.; Niu, Q.; Wang, F.; Kropinski, A. M.; Jiang, X.; Peng, S.; Li, S.; Tong, Y.

10.1101/2021.07.15.452192 — bioinformatics — Posted on 2021-07-15

2075 Assessing the matrix effects of pigmented and non-pigmented salmon during multi-residue antibiotic analysis with liquid chromatography coupled to tandem mass spectrometry

Emami, S.; Taha, A. Y.

10.1101/2021.07.15.452301 — biochemistry — Posted on 2021-07-15

2076 Phylogenomic and mitogenomic data can accelerate inventorying of tropical beetles during the current biodiversity crisis

Motyka, M.; Kusy, D.; Bocek, M.; Bilkova, R.; Bocak, L.

10.1101/2021.07.15.452170 — evolutionary biology — Posted on 2021-07-15

2077 High-resolution single cell transcriptome analysis of zebrafish sensory hair cell regeneration

Baek, S.; Tran, N. T. T.; Diaz, D. C.; Tsai, Y.-Y.; Piotrowski, T.

10.1101/2021.07.15.452338 — developmental biology — Posted on 2021-07-15

2078 Phenotypic and genomic diversification in complex carbohydrate degrading human gut bacteria

Pudlo, N. A.; Urs, K.; Crawford, R.; Pirani, A.; Atherly, T.; Jimenez, R.; Terrapon, N.; Henrissat, B.; Peterson, D. A.; Ziemer, C.; Snitkin, E. S.; Martens, E.

10.1101/2021.07.15.452266 — microbiology — Posted on 2021-07-15

2079 IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay

Akaki, K.; Ogata, K.; Yamauchi, Y.; Iwai, N.; Tse, K. M.; Hia, F.; Mochizuki, A.; Ishihama, Y.; Mino, T.; Takeuchi, O.

10.1101/2021.07.15.452458 — immunology — Posted on 2021-07-15

2080 Fatty Alcohols, a Minor Component of the Tree Tobacco Surface Wax, Reduce Insect Herbivory

Negin, B.; Shachar, L.; Meir, S.; Ramirez, C. C.; Horowitz, A. R.; Jander, G.; Aharoni, A.

10.1101/2021.07.15.452450 — plant biology — Posted on 2021-07-15

2081 INFIMA leverages multi-omics model organism data to identify effector genes of human GWAS variants

Dong, C.; Simonett, S. P.; Shin, S.; Stapleton, D. S.; Schueler, K. L.; Churchill, G. A.; Lu, L.; Liu, X.; Jin, F.; Li, Y.; Attie, A. D.; Keller, M. P.; Keles, S.

10.1101/2021.07.15.452422 — bioinformatics — Posted on 2021-07-15

2082 Potato juice, a starch industry waste, as a cost-effective medium for the biosynthesis of bacterial cellulose

Ciecholewska-Jusko, D.; Broda, M.; Zywicka, A.; Styburski, D.; Sobolewski, P.; Goracy, K.; Migdal, P.; Junka, A.; Fijalkowski, K.

10.1101/2021.07.15.452442 — bioengineering — Posted on 2021-07-15

2083 Oncogenic truncations of ASXL1 enhance a motif for BRD4 ET-domain binding

Burgess, A. E.; Kleffmann, T.; Mace, P. D.

10.1101/2021.07.15.452438 — biochemistry — Posted on 2021-07-15

2084 Reviewing the consequences of genetic purging on the success of rescue programs

Perez-Pereira, N.; Caballero, A.; Garcia-Dorado, A.

10.1101/2021.07.15.452459 — genetics — Posted on 2021-07-15

2085 Evolution of DNA methylation across Ecdysozoa

Engelhardt, J.; Scheer, O.; Stadler, P. F.; Prohaska, S. J.

10.1101/2021.07.15.452454 — evolutionary biology — Posted on 2021-07-15

2086 Late-acting self-incompatible system, preferential allogamy and delayed selfing in the heterostylous invasive populations of Ludwigia grandiflora subsp. hexapetala

Portillo Lemus, L. O.; Harang, M.; Bozec, M.; Haury, J.; Stoeckel, S.; Barloy, D.

10.1101/2021.07.15.452457 — ecology — Posted on 2021-07-15

2087 RAD51AP1 compensates for the loss of RAD54 in homology-directed DNA repair

Selemenakis, P.; Sharma, N.; Kwon, Y.; Uhrig, M.; Sung, P.; Wiese, C.

10.1101/2021.07.15.452469 — cell biology — Posted on 2021-07-15

2088 Effect of Geobacter metallireducens nanowire on electron transfer efficiency in MFC

Liu, S.; li, f. y.; ran, l. h.

10.1101/2021.07.14.452433 — microbiology — Posted on 2021-07-15

2089 Size-dependent susceptibility of lake phytoplankton to light stress: An implication for succession of large green algae in a deep oligotrophic lake

Kazama, T.; Hayakawa, K.; Nagata, T.; Shimotori, K.; Imai, A.; Komatsu, K.

10.1101/2021.07.15.452429 — microbiology — Posted on 2021-07-15

2090 Large-scale all-optical dissection of motor cortex connectivity reveals a segregated functional organization of mouse forelimb representations

Resta, F.; Montagni, E.; Vito, G. d.; Scaglione, A.; Allegra Mascaro, A. L.; Pavone, F. S.

10.1101/2021.07.15.452461 — neuroscience — Posted on 2021-07-15

2091 Age-Related Changes in the Rhesus Macaque Eye

Lin, K.; Tran, T.; Kim, S.; Park, S.; Chen, J.; Stout, J. T.; Chen, R.; Rogers, J.; Yiu, G.; Thomasy, S.; Moshiri, A.

10.1101/2021.07.14.452427 — systems biology — Posted on 2021-07-15

2092 ACORBA: Automated workflow to measure Arabidopsis thaliana root tip angle dynamic

Serre, N. B.; Fendrych, M.

10.1101/2021.07.15.452462 — plant biology — Posted on 2021-07-15

2093 Large-scale identification of viral quorum sensing systems reveal convergent evolution of density-dependent sporulation-hijacking in bacteriophages

Bernard, C.; Li, Y.; Lopez, P.; Bapteste, E.

10.1101/2021.07.15.452460 — bioinformatics — Posted on 2021-07-15

2094 Influence of Strain Post-Processing on Brain Injury Prediction

Fahlstedt, M.; Meng, S.; Kleiven, S.

10.1101/2021.07.15.452485 — bioengineering — Posted on 2021-07-15

2095 Inhibitory control performance is repeatable across years and contexts in a wild bird population

Davidson, G.; Reichert, M. S.; Coomes, J. R.; Kulahci, I.; de la Hera, I.; Quinn, J.

10.1101/2021.07.15.452478 — animal behavior and cognition — Posted on 2021-07-15

2096 Challenges and costs of asexuality: Variation in premeiotic genome duplication in gynogenetic hybrids from Cobitis taenia complex.

Dedukh, D.; Marta, A.; Janko, K.

10.1101/2021.07.15.452483 — genetics — Posted on 2021-07-15

2097 Phylogeny, evolution, and classification of the ant genus Lasius, the tribe Lasiini, and the subfamily Formicinae (Hymenoptera: Formicidae)

Boudinot, B. E.; Borowiec, M. L.; Prebus, M. M.

10.1101/2021.07.14.452383 — evolutionary biology — Posted on 2021-07-15

2098 Gene Evolutionary Trajectories in M. tuberculosis Reveal Temporal Signs of Selection

Chiner-Oms, A.; Lopez, M. G.; Comas, I.

10.1101/2021.07.15.452434 — evolutionary biology — Posted on 2021-07-15

2099 Calcium signaling mediates mechanotransduction at the multicellular stage of Dictyostelium discoideum

Hashimura, H.; Morimoto, Y. V.; Hirayama, Y.; Ueda, M.

10.1101/2021.07.14.452436 — developmental biology — Posted on 2021-07-15

2100 An efficient polymer cocktail-based transportation method for cartilage tissue, yielding chondrocytes with enhanced hyaline cartilage expression during in vitro culturing

Katoh, S.; Yoshioka, H.; Suzuki, S.; Nakajima, H.; Iwasaki, M.; Senthilkumar, R.; Preethy, S.; Abraham, S. J.

10.1101/2021.07.14.452414 — cell biology — Posted on 2021-07-15

2101 Differential requirements for mitochondrial electron transport chain components in the adult murine liver

Lesner, N. P.; Wang, X.; Frank, A.; House, S.; Shelton, S. D.; McFadden, D. G.; DeBerardinis, R. J.; Mishra, P.

10.1101/2021.07.15.452466 — cell biology — Posted on 2021-07-15

2102 Reciprocal regulation of Shh trafficking and H2O2 levels via a noncanonical BOC-Rac1 pathway

Thauvin, M.; Amblard, I.; Rampon, C.; Mourton, A.; Queguiner, I.; Li, C.; Gautier, A.; Joliot, A.; Volovitch, M.; VRIZ, S.

10.1101/2021.07.15.452471 — cell biology — Posted on 2021-07-15

2103 DNA double strand break position leads to distinct gene expression changes and regulates VSG switching pathway choice.

Thivolle, A.; Mehnert, A.-K.; Tihon, E.; McLaughlin, E.; Dujeancourt-Henry, A.; Glover, L.

10.1101/2021.07.15.452463 — molecular biology — Posted on 2021-07-15

2104 The Antimicrobial Efficacy Of Plasma Activated Water Is Modulated By Reactor Design And Water Composition

Rothwell, J. G.; Alam, D.; Carter, D. A.; Soltani, B.; McConchie, R.; Zhou, R.; Cullen, P. J.; Mai-Prochnow, A.

10.1101/2021.07.14.452435 — microbiology — Posted on 2021-07-15

2105 Exploring the metabolic landscape of pancreatic ductal adenocarcinoma cells using genome-scale metabolic modeling

Islam, M. M.; Goertzen, A.; Singh, P. K.; Saha, R.

10.1101/2021.07.14.452356 — systems biology — Posted on 2021-07-15

2106 The DocMaps Framework for representing assertions on research products in an extensible, machine-readable, and discoverable format

McDowell, G. S.; Polka, J. K.; Ross-Hellauer, T.; Stein, G.

10.1101/2021.07.13.452204 — scientific communication and education — Posted on 2021-07-15

2107 Long-Term Protective Effects of Single-Dose infusion of Warm Blood Cardioplegic Solution in a mini-pig model on the background of intraoperative anemia

Yavorovskiy, A. G.; Komarov, R. N.; Kogan, E. A.; Mandel, I. A.; Panov, A. V.; Bagdasarov, P. S.; Bulanova, E. L.; Khalikova, E. Y.; Popov, A. M.

10.1101/2021.07.15.452431 — physiology — Posted on 2021-07-15

2108 Cellular Pharmacology of Curcumin With and Without Piperine

Mahran, R. I.; Shu, P.; Colacino, J.; Hagras, M. M.; Sun, D.; Brenner, D. E.

10.1101/2021.07.14.452424 — pharmacology and toxicology — Posted on 2021-07-15

2109 Nucleotide Biosynthesis Links Glutathione Metabolism to Ferroptosis Sensitivity

Tarangelo, A.; Kim, J. T.; Long, J. Z.; Dixon, S. J.

10.1101/2021.07.14.452394 — cancer biology — Posted on 2021-07-15

2110 Population model of Temnothorax albipennis as a distributed dynamical system II: secret of "chemical reaction" in collective house-hunting in ant colonies is unveiled by operator methods

Qiu, S.

10.1101/2021.07.14.452425 — biophysics — Posted on 2021-07-15

2111 Learning Your Heart Actions From Pulse: ECG Waveform Reconstruction From PPG

Zhu, Q.; Tian, X.; Wong, C.-W.; Wu, M.

10.1101/815258 — bioinformatics — Posted on 2021-07-15

2112 An analytical pipeline for DNA Methylation Array Biomarker Studies

Lu, J.; Korbie, D.; Trau, M.

10.1101/2021.07.14.452293 — bioinformatics — Posted on 2021-07-15

2113 Over-Representation of Potential SP4 Target Genes within Schizophrenia-Risk Genes

Zhou, X.

10.1101/2021.07.14.452377 — genetics — Posted on 2021-07-15

2114 The myotendinous junction marker collagen XXII enables zebrafish postural control learning and optimal swimming performance through its force transmission activity

Malbouyres, M.; Guiraud, A.; Lefrancois, C.; Salamito, M.; Nauroy, P.; Bernard, L.; Sohm, F.; Allard, B.; Ruggiero, F.

10.1101/2021.07.14.452354 — developmental biology — Posted on 2021-07-15

2115 Increased intestinal permeability in an orally-reactive peanut allergy model identifies Angiopoietin like-4 as a biomarker

Steinbach, E. C.; Smeekens, J. M.; Roy, S.; Toyonaga, T.; Cornaby, C.; Perini, L. B.; Berglind, A. E.; Kulis, M. D.; Kim, E. H.; Ferris, M. T.; Furey, T. S.; Burks, A. W.; Sheikh, S. Z.

10.1101/2021.07.14.452416 — cell biology — Posted on 2021-07-15

2116 Ing4-deficiency enhances HSC quiescence and confers resistance to inflammatory stress

Thompson, Z.; Anderson, G. A.; Rodriguez, M.; Gabriel, S.; Binder, V.; Taylor, A. M.; Kathrein, K. L.

10.1101/2021.07.14.452366 — cell biology — Posted on 2021-07-15

2117 HIF-dependent Neuropeptide Y Receptor Y1 and Y5 expression sensitizes hypoxic cells to NPY stimulation

Medeiros, P. J.; Pascetta, S.; Kirsh, S.; Al-Khazraji, B. K.; Uniacke, J.

10.1101/2021.07.14.452372 — molecular biology — Posted on 2021-07-15

2118 Rapid, dose-dependent and efficient inactivation of surface dried SARS-CoV-2 by 254 nm UV-C irradiation

Ruetalo, N.; Businger, R.; Schindler, M.

10.1101/2020.09.22.308098 — microbiology — Posted on 2021-07-15

2119 Structure of bacterial communities in Japanese-style bathrooms: Comparative sequencing of bacteria in shower water and showerhead biofilms using a portable nanopore sequencer

Fujiyoshi, S.; Nishiuchi, Y.; Maruyama, F.

10.1101/2021.07.14.452346 — microbiology — Posted on 2021-07-15

2120 An information theoretic method to resolve millisecond-scale spike timing precision in a comprehensive motor program

Putney, J.; Niebur, T.; Barker, R.; Sponberg, S.

10.1101/2021.07.14.452403 — neuroscience — Posted on 2021-07-15

2121 Alterations in leptin signaling in Amyotrophic Lateral Sclerosis (ALS)

Ferrer-Donato, A.; Contreras, A.; Frago, L. M.; Chowen, J. A.; Fernandez-Martos, C. M.

10.1101/2021.07.14.452319 — neuroscience — Posted on 2021-07-15

2122 A CLEM approach to access to the ultrastructure at the graft interface in Arabidopsis thaliana

Chambaud, C.; Cookson, S. J.; Ollat, N.; Bayer, E. M. F.; Brocard, L.

10.1101/2021.07.13.452258 — plant biology — Posted on 2021-07-15

2123 Modeling Allelic Diversity of Multi-parent Mapping Populations Affects Detection of Quantitative Trait Loci

Odell, S.; Hudson, A. I.; Praud, S.; Dubreuil, P.; Tixier, M.-H.; Ross-Ibarra, J.; Runcie, D. E.

10.1101/2021.07.14.452335 — plant biology — Posted on 2021-07-15

2124 Predicting stable binding modes from simulated dimers of the D76N mutant of β2-microglobulin

Oliveira, N. F. B.; Rodrigues, F. E. P.; Vitorino, J. N. M.; Loureiro, R. J. S.; Faisca, P. F.; Machuqueiro, M.

10.1101/2021.07.14.452361 — biophysics — Posted on 2021-07-15

2125 SvAnna: efficient and accurate pathogenicity prediction for coding and regulatory structural variants in long-read genome sequencing

Danis, D.; Jacobsen, J. O. B.; Balachandran, P.; Zhu, Q.; Yilmaz, F.; Reese, J.; Haimel, M.; Mungall, C. J.; Beck, C.; Lee, C.; Smedley, D.; Robinson, P. N.

10.1101/2021.07.14.452267 — bioinformatics — Posted on 2021-07-15

2126 The E3 ligase RNF115 regulates phagosome maturation and host response to bacterial infection

Bilkei-Gorzo, O.; Heunis, T.; Fabrikova, D.; Marin Rubio, J.-L.; Peltier, J.; Oakley, F.; Härtlova, A.; Trost, M.

10.1101/2021.07.13.452284 — biochemistry — Posted on 2021-07-15

2127 Coastal winds and larval fish abundance indicate a recruitment mechanism for southeast Australian estuarine fisheries

Schilling, H. T.; Hinchliffe, C.; Gillson, J. P.; Miskiewicz, A.; Suthers, I. M.

10.1101/2020.06.24.170068 — ecology — Posted on 2021-07-15

2128 Predation Efficiency upon Clinical Isolates: Bdellovibrio bacteriovorus is Prey Specific and Origin Dependent

Herencias, C.; Saralegui, C.; Halperin, A.; Caballero, J. d. D.; Perez-Viso, B.; Salgado-Briegas, S.; Fernandez-Lanza, V.; Canton, R.; Baquero, F.; Prieto, A.; del Campo, R.

10.1101/2021.07.13.452292 — ecology — Posted on 2021-07-15

2129 Implications of Spike-glycoprotein processing at S1/S2 by Furin, at S2' by Furin and/or TMPRSS2 and shedding of ACE2: cell-to-cell fusion, cell entry and infectivity of SARS-CoV-2

Essalmani, R.; Jain, J.; Susan-Resiga, D.; Andreo, U.; Evagelidis, A.; Derbali, R. M.; Huynh, D.; Dallaire, F.; Laporte, M.; Delpal, A.; Sutto-Ortiz, P.; Coutard, B.; Mapa, C.; Wilcoxen, K.; Decroly, E.; Pham, T.; Cohen, E. A.; Seidah, N. G.

10.1101/2020.12.18.423106 — biochemistry — Posted on 2021-07-15

2130 Implications of Spike-glycoprotein processing at S1/S2 by Furin, at S2' by Furin and/or TMPRSS2 and shedding of ACE2: cell-to-cell fusion, cell entry and infectivity of SARS-CoV-2

Essalmani, R.; Jain, J.; Susan-Resiga, D.; Andreo, U.; Evagelidis, A.; Derbali, M.; Huynh, D.; Dallaire, F.; Laporte, M.; Delpal, A.; Sutto-Ortiz, P.; Coutard, B.; Mapa, C.; Wilcoxen, K.; Decroly, E.; Pham, T. N.; Cohen, E. A.; Seidah, N. G.

10.1101/2021.07.02.450896 — biochemistry — Posted on 2021-07-15

2131 Defining the Immune Responses for SARS-CoV-2-Human Macrophage Interactions

Abdelmoaty, M.; Yeapuri, P.; Machhi, J.; Olson, K.; Shahjin, F.; Zhou, Y.; Jingjing, L.; Pandey, K.; Acharya, A.; Byrareddy, S.; Mosley, L.; Gendelman, H.

10.1101/2021.07.07.449660 — immunology — Posted on 2021-07-15

2132 Assessment of the evolutionary consequence of putative driver mutations in colorectal cancer with spatial multiomic data

Heide, T.; Househam, J.; Cresswell, G. D.; Spiteri, I.; Lynn, C.; Kimberley, C.; Mossner, M.; Zapata, L.; Gabbutt, C.; Ramazzotti, D.; Chen, B.; Fernandez-Mateos, J.; James, C.; Iorio, F.; Berner, A.; Schmidt, M.; Lakatos, E.; Baker, A.-M.; Nichol, D.; Costa, H.; Mitchinson, M.; Werner, B.; Jansen, M.; Barnes, C.; Caravagna, G.; Shibata, D.; Bridgewater, J.; Rodriguez-Justo, M.; Magnani, L.; Graham, T. A.; Sottoriva, A.

10.1101/2021.07.14.451265 — cancer biology — Posted on 2021-07-15

2133 Loss of intermediate filament IFB-1 reduces mobility, density and physiological function of mitochondria in C. elegans sensory neurons

Barmaver, S. N.; Muthaiyan Shanmugam, M.; Chang, Y.; Bhan, P.; Wu, G.-H.; Wagner, O. I.

10.1101/723205 — cell biology — Posted on 2021-07-15

2134 The Series of a Four-node Motif and Coherent Type-1 Feed-forward Loop can Provide Sensitive Detection over Arbitrary Range of Input Signal, thereby Explain Weber's Law in Higher-Order Sensory Processes, and Compute Logarithm

Wadhwa, D.

10.1101/2020.04.08.032193 — systems biology — Posted on 2021-07-15

2135 USP28 deletion and small molecule inhibition destabilises c-Myc and elicits regression of squamous cell lung carcinoma

Ruiz, E. J.; Pinto-Fernandez, A.; Turnbull, A. P.; Lan, L.; Charlton, T. M.; Scott, H. C.; Damianou, A.; Vere, G.; Riising, E. M.; Da Costa, C.; Krajewski, W. W.; Guerin, D.; Kearns, J.; Ioannidis, S.; Katz, M.; McKinnon, C.; O'Connell, J. C.; Moncaut, N.; Rosewell, I.; Nye, E.; Jones, N.; Heride, C.; Gersch, M.; Wu, M.; Dinsmore, C. J.; Hammonds, T. R.; Kim, S.; Komander, D.; Urbe, S.; Clague, M. J.; Kessler, B. M.; Behrens, A.

10.1101/2020.11.17.377705 — cancer biology — Posted on 2021-07-15

2136 Novel amiloride derivatives that inhibit bacterial motility across multiple strains and stator types

Islam, M. I.; Bae, J.; Ishida, T.; Ridone, P.; Lin, J.; Kelso, M. J.; Sowa, Y.; Buckley, B. J.; Baker, M. A.

10.1101/2021.04.13.439105 — microbiology — Posted on 2021-07-15

2137 The 4.4 A structure of the giant Melbournevirus virion belonging to the Marseilleviridae family

Burton-Smith, R. N.; Reddy, H. K. N.; Svenda, M.; Abergel, C.; Okamoto, K.; Murata, K.

10.1101/2021.07.14.452405 — microbiology — Posted on 2021-07-15

2138 Long-range single-molecule mapping of chromatin modification in eukaryotes

Weng, Z.; Ruan, F.; Chen, W.; Xie, Z.; Xie, Y.; Zhang, C.; Chen, Z.; Wang, J.; Sun, Y.; Fang, Y.; Guo, M.; Tong, Y.; Li, Y.; Tang, C.

10.1101/2021.07.08.451578 — genomics — Posted on 2021-07-15

2139 Robust and annotation-free analysis of alternative splicing using short-read scRNA-seq data

Benegas, G.; Fischer, J.; Song, Y. S.

10.1101/2021.04.27.441683 — genomics — Posted on 2021-07-15

2140 Toolkit for Oscillatory Real-time Tracking and Estimation (TORTE)

Schatza, M.; Blackwood, E. B.; Nagrale, S.; Widge, A. S.

10.1101/2021.06.21.449019 — neuroscience — Posted on 2021-07-14

2141 Prolonged partner separation erodes nucleus accumbens transcriptional signatures of pair bonding in male prairie voles

Sadino, J. M.; Bradeen, X. G.; Kelly, C. J.; Walker, D. M.; Donaldson, Z. R.

10.1101/2021.07.14.452355 — neuroscience — Posted on 2021-07-14

2142 Minimal DNA Electron Transfer Catalysts Switched by a Chaotropic Ion

Hoog, T. G.; Pawlak, M. R.; Aufdembrink, L. M.; Bachan, B. R.; Galles, M. B.; Bense, N. B.; Adamala, K. P.; Engelhart, A. E.

10.1101/784561 — synthetic biology — Posted on 2021-07-14

2143 Antibody structure prediction using interpretable deep learning

Ruffolo, J. A.; Sulam, J.; Gray, J. J.

10.1101/2021.05.27.445982 — biophysics — Posted on 2021-07-14

2144 Functional enrichment of alternative splicing events with NEASE reveals insights into tissue identity and diseases

Louadi, Z.; Elkjaer, M. L.; Klug, M.; Lio, C. T.; Fenn, A.; Illes, Z.; Bongiovanni, D.; Baumbach, J.; Kacprowski, T.; List, M.; Tsoy, O.

10.1101/2021.07.14.452376 — bioinformatics — Posted on 2021-07-14

2145 Three-dimensional organization of chromatin associated RNAs and their role in chromatin architecture in human cells

Calandrelli, R.; Wen, X.; Nguyen, T. C.; Chen, C.-J.; Qi, Z.; Chen, W.; Yan, Z.; Wu, W.; Zaleta-Rivera, K.; Hu, R.; Yu, M.; Wang, Y.; Ma, J.; Ren, B.; Zhong, S.

10.1101/2021.06.10.447969 — genomics — Posted on 2021-07-14

2146 Partitioning gene-mediated disease heritability without eQTLs

Weiner, D.; Gazal, S.; Robinson, E. B.; O'Connor, L.

10.1101/2021.07.14.452393 — genetics — Posted on 2021-07-14

2147 Joint Gene Network Construction by Single-Cell RNA Sequencing Data

Dong, M.; He, Y.; Jiang, Y.; Zou, F.

10.1101/2021.07.14.452387 — genetics — Posted on 2021-07-14

2148 Mathematically and biologically consistent framework for presence-absence pairwise indices of diversity

Sizling, A. L.; Tjorve, E.; Tjorve, K. M. C.; Zarsky, J. D.; Keil, P.; Storch, D.

10.1101/2021.07.14.452244 — ecology — Posted on 2021-07-14

2149 Circular-Linear Copulae for Animal Movement Data

Hodel, F.; Fieberg, J. R.

10.1101/2021.07.14.452404 — ecology — Posted on 2021-07-14

2150 Automatic inference of cell neighborhood in 2D and 3D using nuclear markers

Moretti, B.; Alvarez, S. N. R.; Grecco, H. E.

10.1101/2021.07.14.452382 — developmental biology — Posted on 2021-07-14

2151 The 4.4 A structure of the giant Melbournevirus virion belonging to the Marseilleviridae family

Burton-Smith, R. N.; Reddy, H. K. N.; Svenda, M.; Abergel, C.; Okamoto, K.; Murata, K.

10.1101/2021.07.14.452405 — microbiology — Posted on 2021-07-14

2152 OFF-periods reduce the complexity of neocortical activity during sleep

Gonzalez, J.; Cavelli, M.; Tort, A. B.; Torterolo, P.; Rubido, N.

10.1101/2021.06.11.448131 — neuroscience — Posted on 2021-07-14

2153 Parallel processing by distinct classes of principal neurons in the olfactory cortex

Nagappan, S.; Franks, K.

10.1101/2021.07.13.452206 — neuroscience — Posted on 2021-07-14

2154 Task-related hemodynamic responses in human early visual cortex are modulated by task difficulty and behavioral performance

Burlingham, C. S.; Ryoo, M.; Roth, Z. N.; Mirbagheri, S.; Heeger, D. J.; Merriam, E. P.

10.1101/2021.07.14.452398 — neuroscience — Posted on 2021-07-14

2155 Recording Temporal Signals with Minutes Resolution Using Enzymatic DNA Synthesis

Bhan, N. J.; Castinado, A.; Glaser, J. I.; Kalhor, R. K.; Strutz, J.; Boyden, E.; Church, G.; Kording, K. P.; Tyo, K.

10.1101/2021.07.14.452380 — synthetic biology — Posted on 2021-07-14

2156 Quantifying the size and healing of volumetric muscle wounds using 3D Slicer on CT scans in a canine model

Larie, D.; An, G.; Johnson, S. A.; Hoffman, K.; Vodovotz, Y.; Badylak, S.; Cockrell, C.

10.1101/2021.07.13.452185 — physiology — Posted on 2021-07-14

2157 Generic solving of one-compartment toxicokinetic models

CHARLES, S.; Ratier, A.; Lopes, C.

10.1101/2021.05.06.442956 — pharmacology and toxicology — Posted on 2021-07-14

2158 Twisting DNA by Salt

Cruz-León, S.; Vanderlinden, W.; Müller, P.; Forster, T.; Staudt, G.; Lin, Y.-Y.; Lipfert, J.; Schwierz, N.

10.1101/2021.07.14.452306 — biophysics — Posted on 2021-07-14

2159 Cobolt: Joint analysis of multimodal single-cell sequencing data

Gong, B.; Zhou, Y.; Purdom, E.

10.1101/2021.04.03.438329 — bioinformatics — Posted on 2021-07-14

2160 Distribution-based comprehensive evaluation ofmethods for differential expression analysis inmetatranscriptomics

Cho, H.; Liu, C.; Lin, B. M.; Tang, B.; Roach, J.; de Ribeiro, A.; Love, M. I.; Divaris, K.; Wu, D.

10.1101/2021.07.14.452374 — bioinformatics — Posted on 2021-07-14

2161 Scalable Fabrication of 3D Structured Microparticles Using Induced Phase Separation

Lee, S.; de Rutte, J.; Dimatteo, R.; Koo, D.; Di Carlo, D.

10.1101/2021.07.14.451688 — bioengineering — Posted on 2021-07-14

2162 Palmitoylation targets the Calcineurin phosphatase to the Phosphatidylinositol 4-kinase complex at the plasma membrane

Ulengin-Talkish, I.; Parson, M. A.; Jenkins, M. L.; Roy, J.; Shih, A. Z.; St-Denis, N.; Gulyas, G.; Balla, T.; Gingras, A.-C.; Varnai, P.; Conibear, E.; Burke, J. E.; Cyert, M. S.

10.1101/2021.07.14.451536 — biochemistry — Posted on 2021-07-14

2163 Evolutionary repair reveals an unexpected role of the tRNA modification m1G37 in aminoacylation

Clifton, B. E.; Fariz, M. A.; Uechi, G.-I.; Laurino, P.

10.1101/2021.07.14.452415 — biochemistry — Posted on 2021-07-14

2164 Development of epigenetic clocks for New Zealand livestock

Caulton, A.; Dodds, K. G.; McRae, K. M.; Couldrey, C.; Horvath, S.; Clarke, S. M.

10.1101/2021.06.30.450497 — genomics — Posted on 2021-07-14

2165 Efficient and Economical Targeted Insertion in Plant Genomes via Protoplast Regeneration

Hsu, C.-T.; Yuan, Y.-H.; Lin, Y.-C.; Lin, S.; Cheng, Q.-W.; Wu, F.-H.; Sheen, J.; Shih, M.-C.; Lin, C.-S.

10.1101/2021.03.09.434087 — genetics — Posted on 2021-07-14

2166 Retinal ganglion cell-specific genetic regulation in primary open angle glaucoma

Daniszewski, M.; Senabouth, A.; Liang, H. H.; Han, X.; Lidgerwood, G. E.; Hernandez, D.; Sivakumaran, P.; Clarke, J. E.; Lim, S. Y.; Lees, J. G.; Rooney, L.; Gulluyan, L.; Souzeau, E.; Graham, S. L.; Chan, C.-L.; Nguyen, U.; Farbehi, N.; Gnanasambandapillai, V.; McCloy, R. A.; Clarke, L.; Kearns, L.; Mackey, D. A.; Craig, J. E. E.; MacGregor, S.; Powell, J. E.; Pebay, A.; Hewitt, A. W.

10.1101/2021.07.14.452417 — genetics — Posted on 2021-07-14

2167 The dual nature of metacommunity variability

Lamy, T.; Wisnoski, N. I.; Andrade, R. M.; Castorani, M. C.; Compagnoni, A.; Lany, N. K.; Marazzi, L.; Record, S.; Swan, C.; Tonkin, J. D.; Wang, S.; Voelker, N.; Zarnetske, P. L.; Sokol, E. R.

10.1101/2021.04.09.439168 — ecology — Posted on 2021-07-14

2168 The integrated role of resource memory and scent-mediated territoriality in the emergence of home-ranges

Theng, M.; Prowse, T. A.; Cassey, P.; Delean, S.; Bracis, C.

10.1101/2021.05.07.443202 — ecology — Posted on 2021-07-14

2169 Distinct mitochondrial remodeling during early cardiomyocyte development in a human-based stem cell model

Mostafavi, S.; Balafkan, N.; Pettersen, I. K. N.; Nido, G. S.; Siller, R.; Tzoulis, C.; Sullivan, G.; Bindoff, L. A.

10.1101/2021.07.07.451436 — cell biology — Posted on 2021-07-14

2170 The integrity and assay performance of tissue mitochondrial DNA is considerably affected by choice of isolation method

Repoles, B. M.; Gorospe, C. M.; Tran, P.; Nilsson, A. K.; Wanrooij, P. H.

10.1101/2021.02.10.430587 — molecular biology — Posted on 2021-07-14

2171 The Janus-like role of neuraminidase isoenzymes in inflammation

Howlader, M. A.; Demina, E. P.; Samarani, S.; Guo, T.; Ahmad, A.; Pshezhetsky, A. V.; Cairo, C. W.

10.1101/2021.07.14.452400 — immunology — Posted on 2021-07-14

2172 Distinct neurocomputational mechanisms support informational and normative conformity

Mahmoodi, A.; Nili, H.; Bang, D.; Mehring, C.; Bahrami, B.

10.1101/728428 — neuroscience — Posted on 2021-07-14

2173 Nonlinear Reconfiguration of Network Edges, Topology and Information Content During an Artifical Learning Task

Shine, J. M.; Li, M.; Koyejo, O.; Fulcher, B.; Lizier, J. T.

10.1101/2020.09.30.321679 — neuroscience — Posted on 2021-07-14

2174 How the healthy ageing brain supports semantic binding during language comprehension

Markiewicz, R.; Segaert, K.; Mazaheri, A.

10.1101/2021.01.15.426707 — neuroscience — Posted on 2021-07-14

2175 Behavioral and Neural Representations en route to Intuitive Action Understanding

Tarhan, L.; De Freitas, J.; Konkle, T.

10.1101/2021.04.08.438996 — neuroscience — Posted on 2021-07-14

2176 Fiber tractography bundle segmentation depends on scanner effects, vendor effects, acquisition resolution, diffusion sampling scheme, diffusion sensitization, and bundle segmentation workflow

Schilling, K.; Tax, C. M. W.; Rheault, F.; Hansen, C. B.; Yang, Q.; Yeh, F.-c.; Cai, L. Y.; Anderson, A. W.; Landman, B. A.

10.1101/2021.03.17.435872 — neuroscience — Posted on 2021-07-14

2177 Targeting KRAS-mutant stomach/colorectal tumours by disrupting the ERK2-p53 complex

Lang, J.-Y.; Wang, X.; Xie, Q.; Ji, Y.; Shen, J.; Zhang, Y.; Jiang, F.; Kong, X.; Liu, D.; Zheng, L.; Qing, C.

10.1101/2020.08.12.247460 — cancer biology — Posted on 2021-07-14

2178 Interplay between extreme drift and selectionintensities favors the fixation of beneficial mutations in selfing maize populations

Desbiez-Piat, A.; Le Rouzic, A.; Tenaillon, M.; Dillmann, C.

10.1101/2020.12.22.423930 — evolutionary biology — Posted on 2021-07-14

2179 Recombination facilitates adaptive evolution in rhizobial soil bacteria

Cavassim, M. I. A.; Andersen, S. U.; Bataillon, T.; Schierup, M.

10.1101/2021.01.20.427438 — evolutionary biology — Posted on 2021-07-14

2180 When the whole is less than the sum of its parts: maximum object category information and behavioral prediction in multiscale activation patterns

Karimi-Rouzbahani, H.; Woolgar, A.

10.1101/2021.07.14.452389 — neuroscience — Posted on 2021-07-14

2181 Cortical Magnification in Human Visual Cortex Parallels Task Performance around the Visual Field

Benson, N. C.; Kupers, E. R.; Barbot, A.; Carrasco, M.; Winawer, J.

10.1101/2020.08.26.268383 — neuroscience — Posted on 2021-07-14

2182 Optimal Time Lags from Causal Prediction Model Help Stratify and Forecast Nervous System Pathology

Bermperidis, T.; Rai, R.; Ryu, J.; Zanotto, D.; Agrawal, S. K.; Lalwani, A. K.; Torres, E. B.

10.1101/2021.03.05.434171 — neuroscience — Posted on 2021-07-14

2183 The importance of environmentally-acquired bacterial symbionts for the squash bug (Anasa tristis), a significant agricultural pest

Acevedo, T. S.; Fricker, G. P.; Garcia, J. R.; Alcaide, T.; Berasategui, A.; Stoy, K. S.; Gerardo, N. M.

10.1101/2021.07.14.452367 — ecology — Posted on 2021-07-14

2184 Structural heterogeneity of the microtubule lattice

Guyomar, C.; Ku, S.; Heumann, J.; Bousquet, C.; Guilloux, G.; Gaillard, N.; Heichette, C.; Duchesne, L.; Steinmetz, M. O.; Gibeaux, R.; Chretien, D.

10.1101/2021.07.14.452321 — cell biology — Posted on 2021-07-14

2185 Enhancer-promoter interactions and transcription are maintained upon acute loss of CTCF, cohesin, WAPL, and YY1

Hsieh, T.-H. S.; Cattoglio, C.; Slobodyanyuk, E.; Hansen, A. S.; Darzacq, X.; Tjian, R.

10.1101/2021.07.14.452365 — molecular biology — Posted on 2021-07-14

2186 Hypoxia induces early neurogenesis in human fetal neural stem cells by activating the WNT pathway.

Dey, D.; Joshi, D.; Shrivastava, V.; Singal, C. M. S.; Tyagi, S.; Bhat, M. A.; Jaiswal, P.; Sharma, J. B.; Palanichamy, J. K.; Sinha, S.; Seth, P.; Sen, S.

10.1101/2021.07.14.452315 — neuroscience — Posted on 2021-07-14

2187 PyLipID: A Python package for analysis of protein-lipid interactions from MD simulations

Song, W.; Corey, R. A.; Ansell, B.; Cassidy, K.; Horrell, M.; Duncan, A.; Stansfeld, P. J.; Sansom, M.

10.1101/2021.07.14.452312 — biophysics — Posted on 2021-07-14

2188 Polyacrylamide co-N,N'-methylene bisacrylamide monoliths for high peak capacity HILIC-HRMS of intact proteins at low trifluoroacetic acid content

Passamonti, M.; de Roos, C.; Schoenmakers, P.; Gargano, A.

10.1101/2021.07.14.452317 — biochemistry — Posted on 2021-07-14

2189 Comparing the appetitive learning performance of six European honeybee subspecies in a common apiary

Scheiner, R.; Lim, K.; Meixner, M. D.; Gabel, M. S.

10.1101/2021.07.14.452344 — animal behavior and cognition — Posted on 2021-07-14

2190 Allele-resolved single-cell multi-omics uncovers the dynamics and transcriptional kinetics of X-chromosome upregulation

Lentini, A.; Cheng, H.; Noble, J. C.; Papanicolaou, N.; Coucoravas, C.; Andrews, N.; Deng, Q.; Enge, M.; Reinius, B.

10.1101/2021.07.14.452323 — genomics — Posted on 2021-07-14

2191 The (non) accuracy of mitochondrial genomes for family level phylogenetics: the case of erebid moths (Lepidoptera; Erebidae)

Ghanavi, H. R.; Twort, V.; Hartman, T. J.; Zahiri, R.; Wahlberg, N.

10.1101/2021.07.14.452330 — evolutionary biology — Posted on 2021-07-14

2192 Epigenetically Inherited Mutation Rates Predicted to Maximize Adaptation Rates

Ram, Y.; Pilpel, Y. T.; Lobinska, G. A.

10.1101/2021.07.14.452333 — evolutionary biology — Posted on 2021-07-14

2193 Emergence of a geometric pattern of cell fates from tissue-scale mechanics in the Drosophila eye

Gallagher, K. D.; Mani, M.; Carthew, R. W.

10.1101/2021.07.14.452386 — developmental biology — Posted on 2021-07-14

2194 Autoimmune regulator act in synergism with thymocyte adhesion in the control of lncRNAs in medullary thymic epithelial cells

Duarte, M. J.; Mascarenhas, R. S.; Assis, A. F.; Tanaka, P. P.; Speck-Hernandez, C. A.; Passos, G. A.

10.1101/2021.07.14.452339 — molecular biology — Posted on 2021-07-14

2195 Conversion rate to the secondary conformation state in the binding mode of SARS-CoV-2 spike protein to human ACE2 may predict infectivity efficacy of the underlying virus mutant

Sevenich, M.; van den Heuvel, J.; Gering, I.; Mohrlueder, J.; Willbold, D.

10.1101/2021.07.14.452313 — molecular biology — Posted on 2021-07-14

2196 Mapping Human Transient Transcriptomes Using Single Nucleotide Resolution 4sU Sequencing (SNU-Seq)

Mellor, J.; Lorenz, P.; Lamstaes, A.; Fischl, H. J.; Xi, S.; Saukko-Paavola, A.; Murray, S. C.; Brown, T.; George, C.; Furger, A.; Angel, A.

10.1101/2021.07.14.452379 — molecular biology — Posted on 2021-07-14

2197 Loss of the DYRK1A protein kinase results in reduction of ribosomal protein genes expression, ribosome mass and translation defects

Di Vona, C.; Barba, L.; Ferrari, R.; de la Luna, S.

10.1101/2021.01.21.427583 — molecular biology — Posted on 2021-07-14

2198 Water-soluble tocopherol derivatives inhibit SARS-CoV-2 RNA-dependent RNA polymerase

Pacl, H. T.; Tipper, J. L.; Sevalkar, R. R.; Crouse, A.; Crowder, C.; UAB Precision Medicine Institute, ; Holder, G. D.; Kuhlman, C. J.; Chinta, K. C.; Nadeem, S.; Green, T. J.; Petit, C. M.; Steyn, A. J.; Might, M.; Harrod, K. S.

10.1101/2021.07.13.449251 — microbiology — Posted on 2021-07-14

2199 Repurposing screen highlights broad-spectrum coronavirus antivirals and their host targets

Haid, S.; Matthaei, A.; Winkler, M.; Sake, S. M.; Gunesch, A. P.; Rueckert, J.; Vieyres, G.; Kuehl, D.; Nguyen, T.-T.; Lasswitz, L.; Zapatero, F.; Brogden, G.; Gerold, G.; Wiegmann, B.; Bilitewski, U.; Broenstrup, M.; Schulz, T.; Pietschmann, T.

10.1101/2021.07.14.452343 — microbiology — Posted on 2021-07-14

2200 Xeno-nucleic Acid (XNA) 2'-Fluoro-Arabino Nucleic Acid (FANA) Aptamers to the Receptor Binding Domain of SARS-CoV-2 S Protein Block ACE2 Binding

Alves Ferreira-Bravo, I.; DeStefano, J. J.

10.1101/2021.07.13.452259 — microbiology — Posted on 2021-07-14

2201 A modular protein subunit vaccine candidate produced in yeast confers protection against SARS-CoV-2 in non-human primates

Dalvie, N. C.; Tostanoski, L. H.; Rodriguez-Aponte, S. A.; Kaur, K.; Bajoria, S.; Kumru, O.; Martinot, A. J.; Chandrashekar, A.; McMahan, K.; Mercado, N. B.; Yu, J.; Chang, A.; Giffin, V. M.; Nampanya, F.; Patel, S.; Bowman, L.; Naranjo, C. A.; Yun, D.; Flinchbaugh, Z.; Pessaint, L.; Brown, R.; Velasco, J.; Teow, E.; Cook, A.; Andersen, H.; Lewis, M. G.; Camp, D. L.; Silverman, J. M.; Kleanthous, H.; Joshi, S. B.; Volkin, D. B.; Biswas, S.; Love, J. C.; Barouch, D. H.

10.1101/2021.07.13.452251 — immunology — Posted on 2021-07-14

2202 A conditioned place preference for heroin is signaled by increased dopamine and direct pathway activity and decreased indirect pathway activity in the nucleus accumbens

O'Neal, T. J.; Bernstein, M. X.; MacDougall, D. J.; Ferguson, S. M.

10.1101/2021.07.14.452340 — neuroscience — Posted on 2021-07-14

2203 Spike-based symbolic computations on bit strings and numbers

Kraisnikovic, C.; Maass, W.; Legenstein, R.

10.1101/2021.07.14.452347 — neuroscience — Posted on 2021-07-14

2204 Transcriptional regulation of neural stem cell expansion in adult hippocampus

Guo, N.; McDermott, K.; Shih, Y.-T.; Zanga, H.; Ghosh, D.; Goncalves, T.; Sahay, A.

10.1101/2021.07.14.452351 — neuroscience — Posted on 2021-07-14

2205 Spinal ganglia control nociceptive input to the central nervous system

Han, H.; Ramli, R.; Wang, C.; Liu, C.; Shah, S.; Mullen, P.; Lall, V.; Jones, F.; Shao, J.; Zhang, H.; Jaffe, D. B.; Gamper, N.; Du, X.

10.1101/2021.07.14.452325 — neuroscience — Posted on 2021-07-14

2206 Reciprocal changes in voltage-gated potassium and subthreshold inward currents help maintain firing dynamics of AVPV kisspeptin neurons during the estrous cycle.

Starrett, J. R.; Defazio, R. A.; Moenter, S.

10.1101/2021.07.14.452390 — physiology — Posted on 2021-07-14

2207 Autocrine signaling explains the emergence of Allee effects in cancer cell populations

Gerlee, P.; Altrock, P. M.; Krona, C.; Nelander, S.

10.1101/2021.07.14.452320 — cancer biology — Posted on 2021-07-14

2208 Mining divergent and conserved signals in 5' splicing site sequences

Beckel, M.; Kaufman, B.; Yanovsky, M.; Chernomoretz, A.

10.1101/2021.07.14.452117 — bioinformatics — Posted on 2021-07-14

2209 Cloud-based DIA data analysis module for signal refinement improves accuracy and throughput of large datasets.

Christianson, K. E.; Jaffe, J. D.; Carr, S. A.; Vaca Jacome, A. S.

10.1101/2021.07.14.452243 — bioinformatics — Posted on 2021-07-14

2210 Comethyl: A network-based methylome approach to investigate the multivariate nature of health and disease

Mordaunt, C. E.; Mouat, J. S.; Schmidt, R. J.; LaSalle, J. M.

10.1101/2021.07.14.452385 — bioinformatics — Posted on 2021-07-14

2211 DeeReCT-TSS: A novel meta-learning-based method annotates TSS in multiple cell types based on DNA sequences and RNA-seq data

Zhou, J.; Zhang, B.; Li, H.; Zhou, L.; Li, Z.; Long, Y.-K.; Han, W.; Wang, M.; Cui, H.; Chen, W.; Gao, X.

10.1101/2021.07.14.452328 — bioinformatics — Posted on 2021-07-14

2212 A Gradient-based Spectral Explainability Method for EEG Deep Learning Classifiers

Ellis, C. A.; Sendi, M. S. E.; Miller, R. L.; Calhoun, V. D.

10.1101/2021.07.14.452360 — bioinformatics — Posted on 2021-07-14

2213 An exon-intron split framework to prioritize transcriptional and post-transcriptional regulatory signals and its application to study energy homeostasis in pigs

Marmol-Sanchez, E.; Cirera, S.; Zingaretti, L.; Jacobsen, M. J.; Ramayo-Caldas, Y.; Jorgensen, C. B.; Fredholm, M.; Cardoso, T. F.; Quintanilla, R.; Amills, M.

10.1101/2021.07.14.452370 — genomics — Posted on 2021-07-14

2214 Evolutionary transition to XY sex chromosomes associated with Y-linked duplication of a male hormone gene in a terrestrial isopod

Russell, A.; Borrelli, S.; Fontana, R.; Laricchiuta, J.; Pascar, J.; Becking, T.; Giraud, I.; Cordaux, R.; Chandler, C.

10.1101/2020.05.18.102079 — evolutionary biology — Posted on 2021-07-14

2215 Biological Action at a Distance: Correlated pattern formation in adjacent tessellation domains without communication

Brooke, J. M.; James, S. S.; Jiminez-Rodriguez, A.; Wilson, S. P.

10.1101/2021.07.14.452349 — developmental biology — Posted on 2021-07-14

2216 mtDNA replication in dysfunctional mitochondria promotes deleterious heteroplasmy via the UPRmt

Yang, Q.; Liu, P.; Anderson, N.; Shpilka, T.; Du, Y.; Uma Naresh, N.; Luk, K.; Lavelle, J.; Zeinert, R.; Chien, P.; Wolfe, S.; Haynes, C.

10.1101/2020.09.01.274472 — cell biology — Posted on 2021-07-14

2217 ECM dimensionality tunes actin tension to modulate the endoplasmic reticulum and spheroid phenotype

Kai, F.; Ou, G.; Tourdot, R. W.; Stashko, C.; Gaietta, G.; Swift, M. F.; Volkmann, N.; Long, A. F.; Han, Y.; Huang, H. H.; Northey, J. J.; Leidal, A. M.; Viasnoff, V.; Bryant, D. M.; Guo, W.; Wiita, A. P.; Guo, M.; Dumont, S.; Hanein, D.; Radhakrishnan, R.; Weaver, V. M.

10.1101/2021.07.14.452329 — cell biology — Posted on 2021-07-14

2218 The role of cytosolic polyadenylation element binding protein 2 alternative splicing in hypoxia

Mayo, E. M.; Stevens, S. C.; Ali, A. N.; Moss, C. J.; Lund, S. P.; Nazario-Munoz, G. S.; Chalfant, C. E.; Permuth, J. B.; Westerheide, S. D.; Park, M. A.

10.1101/2020.10.05.325290 — cell biology — Posted on 2021-07-14

2219 Induction of human trophoblast stem-like cells from primed pluripotent stem cells

Jang, Y. J.; Kim, M.; Lee, B.-K.; Kim, J.

10.1101/2021.07.14.452371 — cell biology — Posted on 2021-07-14

2220 hnRNPA1 regulates early translation to replication switch in SARS-CoV-2 life cycle

Kumar, R.; Chander, Y.; Khandelwal, N.; Nagori, H.; Verma, A.; Pal, Y.; Gulati, B. R.; Tripathi, B. N.; Barua, S.; Kumar, N.

10.1101/2021.07.13.452288 — microbiology — Posted on 2021-07-14

2221 Adaptation, spread and transmission of SARS-CoV-2 in farmed minks and related humans in the Netherlands

Lu, L.; Sikkema, R. S.; Velkers, F. C.; Nieuwenhuijse, D. F.; Fischer, E. A. J.; Meijer, P. A.; Bouwmeester-Vincken, N.; Rietveld, A.; Wegdam-Blans, M. C. A.; Tolsma, P.; Koppelman, M.; Smit, L. A. M.; Hakze-van der Honing, R. W.; van der Poel, W. H. M.; van der Spek, A. N.; Spierenburg, M. A. H.; Molenaar, R. J.; de Rond, J.; Augustijn, M.; Woolhouse, M.; Stegeman, A. J.; Lycett, S.; Oude Munnink, B. B.; Koppelman, M. P. G.

10.1101/2021.07.13.452160 — microbiology — Posted on 2021-07-14

2222 Human placental villi immune cells help maintain homeostasis in utero

Konnikova, L.; Toothaker, J. M.; Olaloye, O.; McCourt, B. T.; McCourt, C. C.; Case, R. M.; Liu, P.; Yimlamai, D.; Tseng, G.

10.1101/2021.07.14.452362 — immunology — Posted on 2021-07-14

2223 Balanced release of neuropeptide FF and gonadotropin-releasing hormone 3 modulates male sexual behavior

Umatani, C.; Yoshida, N.; Yamamoto, E.; Akazome, Y.; Mori, Y.; Kanda, S.; Okubo, K.; Oka, Y.

10.1101/2021.07.14.452327 — neuroscience — Posted on 2021-07-14

2224 Nuclear and cytoplasmic huntingtin inclusions exhibit distinct biochemical composition, interactome and ultrastructural properties

Riguet, N.; Mahul-Mellier, A.-L.; Maharjan, N.; Burtscher, J.; Croisier, M.; Knott, G. W.; Hastings, J.; Patin, A.; Reiterer, V.; Farhan, H.; Nazarov, S.; Lashuel, H.

10.1101/2020.07.29.226977 — neuroscience — Posted on 2021-07-14

2225 Striatal fiber photometry reflects primarily non-somatic activity

Legaria, A. A.; Yang, B.; Ahanonu, B.; Licholai, J. A.; Parker, J.; Kravitz, A.

10.1101/2021.01.20.427525 — neuroscience — Posted on 2021-07-14

2226 Tissue Specific Age Dependence of the Cell Receptors Involved in the SARS-CoV-2 Infection

Forst, C. V.; Zeng, L.; Wang, Q.; Zhou, X.; Vatansever, S.; Tu, Z.; Zhang, B.

10.1101/2021.07.13.452256 — systems biology — Posted on 2021-07-14

2227 Bioimage postprocessing based on discrete wavelet transform and Lucy-Richardson deconvolution methods

Bai, H.; Che, B.; Zhao, T.; Zhao, W.; Wang, K.; Zhang, C.; Bai, J.

10.1101/2021.07.14.452302 — biophysics — Posted on 2021-07-14

2228 Achieving dendritic cell subset-specific targeting in vivo by site-directed conjugation of targeting antibodies to nanocarriers

Simon, J.; Fichter, M.; Kuhn, G.; Brueckner, M.; Kappel, C.; Schunke, J.; Grabbe, S.; Landfester, K.; Mailaender, V.

10.1101/2021.07.14.452311 — bioengineering — Posted on 2021-07-14

2229 Population model of Temnothorax albipennis as a distributed dynamical system: I. self-consistent threshold is an emergent property in combination of quorum sensing and chemical perception of limited resource

Qiu, S.

10.1101/2021.07.14.452298 — animal behavior and cognition — Posted on 2021-07-14

2230 The haplotype-resolved reference genome of lemon (Citrus limon L. Burm f.)

Di Guardo, M.; Moretto, M.; Moser, M.; Catalano, C.; Troggio, M.; Deng, Z.; Cestaro, A.; Caruso, M.; Distefano, G.; La Malfa, S.; Bianco, L.; Gentile, A.

10.1101/2021.07.14.452308 — genomics — Posted on 2021-07-14

2231 A Ca2+ wave generates a force during cell extrusion in zebrafish

Yamada, S.; Bessho, Y.; Fijita, Y.; Hosokawa, Y.; Matsui, T.

10.1101/2021.07.14.452309 — cell biology — Posted on 2021-07-14

2232 The J domain of sacsin disrupts intermediate filament assembly

Dabbaghizadeh, A.; Pare, A.; Cheng-Boivin, Z.; Dagher, R.; Minotti, S.; Dicaire, M.-J.; Brais, B.; Young, J. C.; Durham, H. D.; Gentil, B. J.

10.1101/2021.07.14.452331 — cell biology — Posted on 2021-07-14

2233 Ribocutter: Cas9-mediated rRNA depletion from multiplexed riboseq libraries

Wilkins, O. G.; Ule, J.

10.1101/2021.07.14.451473 — molecular biology — Posted on 2021-07-14

2234 A cost-effective and efficient approach for generating and assembling reagents for conducting real-time PCR

Mote, R. D.; V, S. L.; Singh, S. B.; Tiwari, M.; Singh, H.; Srivastava, J.; Tripathi, V.; Seshadri, V.; Majumdar, A.; Subramanyam, D.

10.1101/2021.07.14.452300 — molecular biology — Posted on 2021-07-14

2235 RNase HI depletion strongly potentiates cell killing by rifampicin in mycobacteria

Al-Zubaidi, A.; Cheung, C.-Y.; Cook, G. M.; Taiaroa, G.; Mizrahi, V.; Lott, J. S.; Dawes, S. S.

10.1101/2021.07.14.452003 — microbiology — Posted on 2021-07-14

2236 Regulation of MHC-I and MHC-II by CIITA in transmissible cancers

Ong, C. E. B.; Cheng, Y.; Siddle, H.; Lyons, A. B.; Woods, G. M.; Flies, A. S.

10.1101/2021.07.14.452299 — immunology — Posted on 2021-07-14

2237 Differential effects of early or late exposure to prenatal maternal immune activation on mouse embryonic neurodevelopment

Guma, E.; Bordeleau, M.; Snook, E.; Desrosiers-Gregoire, G.; Gonzalez Ibanez, F.; Picard, K.; Spring, S.; Lerch, J. P.; Nieman, B. J.; Devenyi, G. A.; Tremblay, M.-E.; Chakravarty, M. M.

10.1101/2021.07.14.452084 — neuroscience — Posted on 2021-07-14

2238 NPDS Toolbox: Neural Population (De)Synchronization toolbox for Matlab

Moayeri, M. M.; Hemami, M.; Amani Rad, J.; Parand, K.

10.1101/2021.07.13.452294 — neuroscience — Posted on 2021-07-14

2239 Intake, performance, and feeding behavior of Holstein and Holstein x Gyr heifers grazing intensive managed tropical grasses during the rainy season

Quirino, D. F.; Marcondes, M. I.; Renno, L. N.; Cunha, C. S.; Silva, A. L.; Miller-Cushon, E.; Rotta, P. P.

10.1101/2021.07.13.452261 — zoology — Posted on 2021-07-14

2240 Making Strides in Doctoral-Level Career Outcomes Reporting: Surveying the Landscape of Classification and Visualization Methodologies and Creating a Crosswalk Tool

Collins, T.; Ramadoss, D.; Layton, R.; MacDonald, J.; Wheeler, R.; Bankston, A.; Stayart, C. A.; Hao, Y.; Robinson-Hamm, J.; Sinche, M.; Burghart, S.; Carlsen-Bryan, A.; Eswara, P.; Krasna, H.; Xu, H.; Sullivan, M.

10.1101/2021.07.12.451657 — scientific communication and education — Posted on 2021-07-14

2241 Assessment of the evolutionary consequence of putative driver mutations in colorectal cancer with spatial multiomic data

Sottoriva, A.; Graham, T. A.; Heide, T.; Househam, J.; Cresswell, G. D.; Spiteri, I.; Lynn, C.; Kimberley, C.; Mossner, M.; Zapata, L.; Gabbutt, C.; Ramazzotti, D.; Chen, B.; Fernandez-Mateos, J.; James, C.; Iorio, F.; Berner, A.; Schmidt, M.; Lakatos, E.; Baker, A.-M.; Nichol, D.; Costa, H.; Mitchinson, M.; Werner, B.; Jansen, M.; Barnes, C.; Caravagna, G.; Shibata, D.; Bridgewater, J.; Rodriguez-Justo, M.; Magnani, L.

10.1101/2021.07.14.451265 — cancer biology — Posted on 2021-07-14

2242 R-loop-induced p21 expression following CDC73, CTR9, and PAF1 loss protects cancer cells against replicative catastrophe following WEE1 inhibition

van Bijsterveldt, L.; Landsverk, H. B.; Näshe, V.; Durley, S. C.; Sarkar, S.; Syljuasen, R. G.; Humphrey, T. C.

10.1101/2021.07.14.452205 — cancer biology — Posted on 2021-07-14

2243 Design of complicated all-α protein structures

Sakuma, K.; Kobayashi, N.; Sugiki, T.; Nagashima, T.; Fujiwara, T.; Suzuki, K.; Kobayashi, N.; Murata, T.; Kosugi, T.; Koga, R.; Koga, N.

10.1101/2021.07.14.449347 — biophysics — Posted on 2021-07-14

2244 PROGRAMMED AXON DEATH EXECUTOR SARM1 IS A MULTI-FUNCTIONAL NAD(P)ASE WITH PROMINENT BASE EXCHANGE ACTIVITY, ALL REGULATED BY PHYSIOLOGICAL LEVELS OF NMN, NAD, NADP AND OTHER METABOLITES

Angeletti, C.; Amici, A.; Gilley, J.; Loreto, A.; Trapanotto, A. G.; Antoniou, C.; Coleman, M. P.; Orsomando, G.

10.1101/2021.07.14.451805 — biochemistry — Posted on 2021-07-14

2245 Systematic in vivo interrogation identifies novel enhancers and silencers associated to Atrial Fibrillation

Victorino, J.; Rollan, I.; Rouco, R.; Adan, J.; Manzanares, M.

10.1101/2021.07.14.452222 — genomics — Posted on 2021-07-14

2246 Lightning Fast and Highly Sensitive Full-Length Single-cell sequencing using FLASH-Seq

Hahaut, V.; Pavlinic, D.; Cowan, C. S.; Picelli, S.

10.1101/2021.07.14.452217 — genomics — Posted on 2021-07-14

2247 Rapid sequence evolution is associated with genetic incompatibilities in the plastid Clp complex

Abdel-Ghany, S. E.; LaManna, L. M.; Svab, Z.; Harroun, H. E.; Maliga, P.; Sloan, D. B.

10.1101/2021.07.13.452280 — evolutionary biology — Posted on 2021-07-14

2248 Entangling snakebite dynamics: the spatiotemporal role of rainfall on snake envenoming in Colombia

Bravo-Vega, C.; Santos-Vega, M.; Cordovez, J. M.

10.1101/2021.07.13.452215 — ecology — Posted on 2021-07-14

2249 Cylcop: An R Package for Circular-Linear Copulae with Angular Symmetry

Hodel, F. H.; Fieberg, J. R.

10.1101/2021.07.14.452253 — ecology — Posted on 2021-07-14

2250 Temporal Analyses of Postnatal Liver Development and Maturation by Single Cell Transcriptomics

Liang, Y.; Kaneko, K.; Xin, B.; Lee, J.; Sun, X.; Zhang, K.; Feng, G.-S.

10.1101/2021.07.14.451852 — developmental biology — Posted on 2021-07-14

2251 Synergistic interactions between Stachybotrys chartarum and other indoor fungal species in moisture-damaged houses

Chakravarty, P.

10.1101/2021.07.13.452289 — microbiology — Posted on 2021-07-14

2252 An osmotic laxative renders mice susceptible to prolonged Clostridioides difficile colonization and hinders clearance

Tomkovich, S.; Taylor, A.; King, J.; Colovas, J.; Bishop, L.; McBride, K.; Royzenblat, S.; Lesniak, N. A.; Bergin, I. L.; Schloss, P. D.

10.1101/2021.07.13.452287 — microbiology — Posted on 2021-07-14

2253 Trophic status and local conditions affect microbial potential for denitrification versus internal nitrogen cycling in lake sediments

Baumann, K. B. L.; Thoma, R.; Callbeck, C. M.; Niederdorfer, R.; Schubert, C.; Müller, B.; Lever, M. A.; Bürgmann, H.

10.1101/2021.07.12.452135 — microbiology — Posted on 2021-07-14

2254 Correlated transcriptional responses provide insights into the synergy mechanisms of the furazolidone, vancomycin and sodium deoxycholate triple combination in Escherichia coli

Olivera, C.; Cox, M. P.; Rowlands, G. J.; Rakonjac, J.

10.1101/2021.07.13.452286 — microbiology — Posted on 2021-07-14

2255 Candida auris is rendered non-viable by medium-chain fatty acids

Green, K. R.; Gunsalus, K. T. W.; De Jesus, M.

10.1101/2021.07.13.452291 — microbiology — Posted on 2021-07-14

2256 Perturb-map enables CRISPR genomics with spatial resolution and identifies regulators of tumor immune composition

Dhainaut, M.; Rose, S. A.; Akturk, G.; Wroblewska, A.; Sook Park, E.; Nielsen, S. R.; Buckup, M.; Roudko, V.; Pia, L.; Le Berichel, J.; Bektesevic, A.; Lee, B. H.; Baccarini, A.; Bhardwaj, N.; Rahman, A. H.; Gnjatic, S.; Pe'er, D.; Merad, M.; Brown, B. D.

10.1101/2021.07.13.451021 — immunology — Posted on 2021-07-14

2257 Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer's disease

Xia, Z.; Prescott, E.; Leah, T.; Dakin, H.; Dimou, E.; Zuo, Y.; Zhang, Y. P.; Lam, J. Y. L.; Danial, J. S. H.; Jiang, H.; Mortiboys, H. J.; Thornton, P.; Crowther, D. C.; Holtzman, D. M.; Ranasinghe, R. T.; Klenerman, D.; De, S.

10.1101/2021.07.13.452239 — neuroscience — Posted on 2021-07-14

2258 Trips and Neurotransmitters: Discovering Principled Patterns across 6,850 Hallucinogenic Experiences

Ballentine, G.; Friedman, S. F.; Bzdok, D.

10.1101/2021.07.13.452263 — neuroscience — Posted on 2021-07-14

2259 Effects of sub-threshold transcutaneous auricular vagus nerve stimulation on cerebral blood flow

Chen, C.; Mao, Y.; Falahpour, M.; MacNiven, K. H.; Heit, G.; Sharma, V.; Alataris, K.; Liu, T. T.

10.1101/2021.07.13.451709 — neuroscience — Posted on 2021-07-14

2260 Muscle effort is best minimized by the right-dominant arm in the gravity field

Poirier, G.; Lebigre, M.; Mourey, F.; Papaxanthis, C.; Gaveau, J.

10.1101/2021.07.13.452146 — neuroscience — Posted on 2021-07-14

2261 Cortical cell ensemble control of past experience-dependent memory updating

Suzuki, A.; Kosugi, S.; Murayama, E.; Sasakawa, E.; Ohkawa, N.; Konno, A.; Hirai, H.; Inokuchi, K.

10.1101/2021.07.13.452275 — neuroscience — Posted on 2021-07-14

2262 Metabolic endotoxemia is dictated by the type of lipopolysaccharide

Anhe, F. F.; Barra, N. G.; Cavallari, J. F.; Henriksbo, B. D.; Schertzer, J.

10.1101/2021.07.13.452270 — physiology — Posted on 2021-07-14

2263 Nitrogen uptake and macronutrients distribution in mango trees (cv. Keitt) under three N fertigation treatments

Silber, A.; Goldberg, T.; Shapira, O.; Hochberg, U.

10.1101/2021.07.13.452282 — physiology — Posted on 2021-07-14

2264 Caveolin-1 temporal modulation enhances trastuzumab and trastuzumab-drug conjugate efficacy in heterogeneous gastric cancer

Pereira, P. M. R.; Mandleywala, K.; Monette, S.; Lumish, M.; Tully, K. M.; Cornejo, M.; Mauguen, A.; Ragupathi, A.; Mattar, M.; Janjigian, Y. Y.; Lewis, J. S.

10.1101/2021.07.13.452260 — cancer biology — Posted on 2021-07-14

2265 The Polarization Dependence of 2D IR Cross-Peaks Distinguishes Parallel-Stranded and Antiparallel-Stranded DNA G-quadruplexes

Price, D. A.; Wedamulla, P.; Hill, T. D.; Loth, T. M.; Moran, S. D.

10.1101/2021.07.13.452271 — biophysics — Posted on 2021-07-14

2266 SpiderLearner: An ensemble approach to Gaussian graphical model estimation

Shutta, K. H.; Balzer, L. B.; Scholtens, D. M.; Balasubramanian, R.

10.1101/2021.07.13.452248 — bioinformatics — Posted on 2021-07-14

2267 CLPTM1L is a lipid scramblase involved in glycosylphosphatidylinositol biosynthesis

Wang, Y.; Menon, A. K.; Maki, Y.; Liu, Y.-S.; Iwasaki, Y.; Fujita, M.; Guerrero, P. A.; Silva, D. V.; Seeberger, P. H.; Murakami, Y.; Kinoshita, T.

10.1101/2021.07.12.451801 — biochemistry — Posted on 2021-07-14

2268 A hyperthermoactive-Cas9 editing tool reveals the role of a unique arsenite methyltransferase in the arsenic resistance system of Thermus thermophilus HB27

Gallo, G.; Mougiakos, I.; Bianco, M.; Carbonaro, M.; Carpentieri, A.; Illiano, A.; Pucci, P.; Bartolucci, S.; van der Oost, J.; Fiorentino, G.

10.1101/2021.07.12.452139 — biochemistry — Posted on 2021-07-14

2269 Estimating dispersal rates and locating genetic ancestors with genome-wide genealogies

Osmond, M.; Coop, G.

10.1101/2021.07.13.452277 — evolutionary biology — Posted on 2021-07-14

2270 A Lethal Genetic Incompatibility between Naturally Hybridizing Species in Mitochondrial Complex I

Moran, B. M.; Payne, C. Y.; Powell, D. L.; Iverson, E. N.; Banerjee, S. M.; Langdon, Q. K.; Gunn, T. R.; Liu, F.; Matney, R.; Singhal, K.; Leib, R. D.; Hernandez-Perez, O.; Corbett-Detig, R.; Schartl, M.; Havird, J. C.; Schumer, M.

10.1101/2021.07.13.452279 — evolutionary biology — Posted on 2021-07-14

2271 Electron Cryo-Tomography Structure of Axonemal Doublet Microtubule from Tetrahymena thermophila

Li, S.; Fernandez, J.-J.; Fabritius, A. S.; Agard, D.; Winey, M.

10.1101/2021.07.13.452106 — cell biology — Posted on 2021-07-14

2272 Mapping the subcortical connectivity of the human default mode network

Li, J.; Curley, W. H.; Guerin, B.; Dougherty, D. D.; Dalca, A. V.; Fischl, B.; Horn, A.; Edlow, B. L.

10.1101/2021.07.13.452265 — neuroscience — Posted on 2021-07-14

2273 Cellular resolution anatomical and molecular atlases for prenatal human brains

Ding, S.-L.; Royall, J. J.; Lesnar, P.; Facer, B. A. C.; Smith, K. A.; Wei, Y.; Brouner, K.; Dalley, R. A.; Dee, N.; Dolbeare, T. A.; Ebbert, A.; Glass, I. A.; Glattfelter, K.; Keller, N. H.; Lee, F.; Lemon, T. A.; Nyhus, J.; Pendergraft, J.; Reid, R.; Sarreal, M.; Shapovalova, N. V.; Szafer, A.; Phillips, J. W.; Sunkin, S. M.; Hohmann, J. G.; Jones, A. R.; Hawrylycz, M. J.; Hof, P. R.; Ng, L.; Bernard, A.; Lein, E. S.

10.1101/2021.07.14.452297 — neuroscience — Posted on 2021-07-14

2274 Learning spatio-temporal properties of hippocampal place cells

Lian, Y.; Burkitt, A. N.

10.1101/2021.07.13.452268 — neuroscience — Posted on 2021-07-14

2275 Pfam domain adaptation profiles reflect plant species' evolutionary history

Jensen, S. E.; Buckler, E. S.

10.1101/2021.07.13.452250 — plant biology — Posted on 2021-07-14

2276 Global change differentially modulates coral physiology and suggests future shifts in Caribbean reef assemblages

Bove, C. B.; Davies, S. W.; Ries, J. B.; Umbanhowar, J.; Thomasson, B. C.; Farquhar, E. B.; McCoppin, J. A.; Castillo, K. D.

10.1101/2021.07.13.452173 — ecology — Posted on 2021-07-14

2277 Dicamba drift alters plant-herbivore interactions at the agro-ecological interface

Johnson, N. M.; Baucom, R. S.

10.1101/2021.07.13.452219 — ecology — Posted on 2021-07-14

2278 Livestock as vectors of organic matter and nutrient loading in aquatic ecosystems in African savannas

Iteba, J. O.; Hein, T.; Singer, G.; Masese, F. O.

10.1101/2021.07.13.452213 — ecology — Posted on 2021-07-14

2279 Motor memories of object dynamics are categorically organized

Cesanek, E.; Zhang, Z.; Ingram, J. N.; Wolpert, D. M.; Flanagan, J. R.

10.1101/2021.07.13.452183 — neuroscience — Posted on 2021-07-14

2280 +microstate: A MATLAB toolbox for brain microstate analysis in sensor and cortical EEG/MEG

Tait, L.; Zhang, J.

10.1101/2021.07.13.452193 — neuroscience — Posted on 2021-07-14

2281 PD-1 in hippocampal neurons regulates excitability, synaptic plasticity, and cognition

Zhao, J.; Bang, S.; McGinnis, A.; Furutani, K.; Jiang, C.; Roberts, A.; Donnelly, C. R.; He, Q.; Ko, M.-C.; Wang, H.; Palmiter, R.; Ji, R.-R.

10.1101/2021.07.13.451894 — neuroscience — Posted on 2021-07-14

2282 Consistent coordination patterns provide near perfect behavior decoding in a comprehensive motor program for insect flight

Putney, J.; Angjelichinoski, M.; Ravier, R.; Ferrari, S.; Tarokh, V.; Sponberg, S.

10.1101/2021.07.13.452211 — neuroscience — Posted on 2021-07-14

2283 Memory-paced tapping to auditory rhythms: Effects of rate, speech and motor-engagement

Kliger Amrani, A.; Zion Golumbic, E.

10.1101/2021.07.13.452153 — neuroscience — Posted on 2021-07-14

2284 Nuclear Factor I in neurons, glia and during the formation of Muller glia-derived progenitor cells in avian, porcine and primate retinas

El-Hodiri, H.; Campbell, W.; Kelly, L.; Hawthorn, E.; Schwartz, M.; jalligampala, a.; McCall, M.; Meyer, K.; Fischer, A. J.

10.1101/2021.07.13.451621 — neuroscience — Posted on 2021-07-14

2285 A model of mitochondrial ATP synthase deficiencies. The role of mitochondrial carriers.

Mazat, J.-P.; Devin, A.; Yoboue, E.; Ransac, S.

10.1101/2021.07.13.452228 — systems biology — Posted on 2021-07-14

2286 gpuZoo: Cost-effective estimation of gene regulatory networks using the Graphics Processing Unit

Ben Guebila, M.; Morgan, D. C.; Glass, K.; Kuijjer, M. L.; DeMeo, D. L.; Quackenbush, J.

10.1101/2021.07.13.452214 — systems biology — Posted on 2021-07-14

2287 Inferring viral occurrence patterns through a synthetic data simulation

Pimenoff, V. N.; Cleries, R.

10.1101/2021.07.13.452220 — synthetic biology — Posted on 2021-07-14

2288 Image-based assessment of plant disease progression identifies new genetic loci for resistance

Meline, V.; Caldwell, D.; Kim, B.-S. S.; Baireddy, S.; Yang, C.; Sparks, E. E.; Delp, E. J.; Iyer-Pascuzzi, A. S.

10.1101/2021.07.13.452064 — plant biology — Posted on 2021-07-14

2289 Engineering sorghum for higher 4-hydroxybenzoic acid content

Lin, C.-Y.; Tian, Y.; Nelson-Vasilchik, K.; Hague, J.; Kakumanu, R.; Lee, M. Y.; Trinh, J.; Northen, T.; Baidoo, E.; Kausch, A.; Scheller, H.; Eudes, A.

10.1101/2021.07.13.452095 — plant biology — Posted on 2021-07-14

2290 Aberrant enteric neuromuscular system and dysbiosis in amyotrophic lateral sclerosis

Zhang, Y.-g.; Ogbu, D.; Garrett, S.; Xia, Y.; Sun, J.

10.1101/2021.07.13.452097 — physiology — Posted on 2021-07-14

2291 Dual effects of presynaptic membrane mimetics on α-synuclein amyloid aggregation

Lin, Y.; Ito, D.; Yoo, J. M.; Lim, M. H.; Yu, W. K.; Kawata, Y.; Lee, Y.-H.

10.1101/2021.07.13.452016 — biophysics — Posted on 2021-07-14

2292 Stochastic model of T Cell repolarization during target elimination (II)

Hornak, I.; Rieger, H.

10.1101/2021.07.13.452186 — biophysics — Posted on 2021-07-14

2293 Capsaicin alters human NaV1.5 mechanosensitivity

Cowan, L. M.; Strege, P. R.; Rusinova, R.; Andersen, O. S.; Beyder, A.; Farrugia, G.

10.1101/2021.07.13.452086 — biophysics — Posted on 2021-07-14

2294 Infinite re-reading of single proteins at single-amino-acid resolution using nanopore sequencing

Brinkerhoff, H.; Kang, A. C. W.; Liu, J.; Aksimentiev, A.; Dekker, C.

10.1101/2021.07.13.452225 — biophysics — Posted on 2021-07-14

2295 Binding Free energy Decomposition and Multiple Unbinding Paths of Buried Ligands in a PreQ1 Riboswitch

Hu, G.; Zhou, H.-X.

10.1101/2021.07.13.452201 — biophysics — Posted on 2021-07-14

2296 MetaFun: Unveiling sex differences in multiple omics studies through comprehensive functional meta-analysis

Malmierca-Merlo, P.; Sanchez-Garcia, R.; Grillo-Risco, R.; Perez-Diez, I.; Catala-Senent, J. F.; de la Iglesia-Vaya, M.; Hidalgo, M. R.; Garcia-Garcia, F.

10.1101/2021.07.13.451905 — bioinformatics — Posted on 2021-07-14

2297 A Structure-based B-cell Epitope Prediction Model Through Combing Local and Global Features

Lu, S.; Li, Y.; Nan, X.; Zhang, S.

10.1101/2021.07.13.452188 — bioinformatics — Posted on 2021-07-14

2298 Aspiration-assisted freeform bioprinting of mesenchymal stem cell spheroids within alginate microgels

Kim, M. H.; Banerjee, D.; Celik, N.; Ozbolat, I. T.

10.1101/2021.07.13.452209 — bioengineering — Posted on 2021-07-14

2299 Prolactin and prolactin receptor expression in the HPG axis and crop sac during parental care in both sexes of a biparental bird (Columba livia)

Farrar, V. S.; Harris, R. M.; Austin, S. H.; Nava Ultreras, B. M.; Booth, A. M.; Angelier, F.; Lang, A.; Feustel, T.; Lee, C.; Bond, A.; MacManes, M. D.; Calisi, R. M.

10.1101/2021.07.13.452208 — animal behavior and cognition — Posted on 2021-07-14

2300 Equatorial to Polar genomic variability of the microalgae Bathycoccus prasinos

Leconte, J.; Timsit, Y.; Delmont, T. O.; Lescot, M.; Piganeau, G.; Wincker, P.; Jaillon, O.

10.1101/2021.07.13.452163 — genomics — Posted on 2021-07-14

2301 Active enhancers strengthen TAD insulation by bRNA mediated CTCF enrichment at the TAD boundaries

Islam, Z.; Saravanan, B.; Walavalkar, K.; Farooq, U.; Singh, A. K.; Thakur, J.; Pandit, A.; Sabarinathan, R.; Henikoff, S.; Notani, D.

10.1101/2021.07.13.452118 — genomics — Posted on 2021-07-14

2302 Robust Acquisition of High Resolution Spatial Transcriptomes from Preserved Tissues with Immunofluorescence Based Laser Capture Microdissection

Zhang, X.; Hu, C.; Huang, C.; Wei, Y.; Li, X.; Hu, M.; Li, H.; Wu, J.; Czajkowsky, D. M.; Guo, Y.; Shao, Z.

10.1101/2021.07.13.452123 — genomics — Posted on 2021-07-14

2303 PAC: Highly accurate quantification of allelic gene expression for population and disease genetics

Saukkonen, A.; Kilpinen, H.; Hodgkinson, A.

10.1101/2021.07.13.452202 — genomics — Posted on 2021-07-14

2304 Benchmarking ultra-high molecular weight DNA preservation methods for long-read and long-range sequencing

10.1101/2021.07.13.451380 — genomics — Posted on 2021-07-14

2305 When Does Mutualism Offer a Competitive Advantage? A Game-Theoretic Analysis of Host-Host Competition in Mutualism

Halloway, A. H.; Heath, K. D.; McNickle, G. G.

10.1101/2021.07.13.452216 — evolutionary biology — Posted on 2021-07-14

2306 Statistics of the number of equilibria in random social dilemma evolutionary games with mutation

Duong, M. H.; Han, T. A.

10.1101/2021.07.13.452172 — evolutionary biology — Posted on 2021-07-14

2307 Pulling on multiple threads of evidence to reveal tree species coexistence

McNickle, G. G.; Ritzi, M. V.; Blackstone, K. M. S.; Couture, J. J.; Nelson, T.; Hardiman, B. S.; Montague, M. S.; Jacobs, D. F.

10.1101/2021.07.13.452199 — ecology — Posted on 2021-07-14

2308 The roles of NADPH oxidases during adult zebrafish fin regeneration

Chopra, K.; Folkmanaite, M.; Stockdale, L.; Shathish, V.; Ishibashi, S.; Bergin, R.; Amich, J.; Amaya, E.

10.1101/2021.07.13.452203 — developmental biology — Posted on 2021-07-14

2309 IL7R is required for hematopoietic stem cell reconstitution of tissue-resident lymphoid cells

Worthington, A. K.; Cool, T. S.; Poscablo, D. M.; Hussaini, A.; Beaudin, A. E.; Forsberg, E. C.

10.1101/2021.07.13.452134 — cell biology — Posted on 2021-07-14

2310 The ternary complex CEP90, FOPNL and OFD1 specifies the future location of centriolar distal appendages, and promotes their assembly

Le Borgne, P.; Laporte, M. H.; Greibill, L.; Lemullois, M.; Temagoult, M.; Rosnet, O.; Le Guennec, M.; Lignieres, L.; Chevreux, G.; Koll, F.; Hamel, V.; Guichard, P.; Tassin, A.-M.

10.1101/2021.07.13.452210 — cell biology — Posted on 2021-07-14

2311 Parallel processing by distinct classes of principal neurons in the olfactory cortex

Nagappan, S.; Franks, K.

10.1101/2021.07.13.452206 — neuroscience — Posted on 2021-07-14

2312 Quantifying the size and healing of volumetric muscle wounds using 3D Slicer on CT scans in a canine model

Larie, D.; An, G.; Johnson, S. A.; Vodovotz, Y.; Badylak, S.; Cockrell, C.

10.1101/2021.07.13.452185 — physiology — Posted on 2021-07-14

2313 Long-read transcriptome sequencing analysis with IsoTools

Lienhard, M.; van den Beucken, T.; Claiment, F.; Boerno, S.; Hochradel, M.; Timmermann, B.; Vingron, M.; Herwig, R.

10.1101/2021.07.13.452091 — genetics — Posted on 2021-07-14

2314 Neo-sex chromosome evolution shapes sex-dependent asymmetrical introgression barrier

Wang, S.; Nalley, M. J.; Chatla, K.; Aldaimalani, R.; MacPherson, A.; Wei, K.; Corbett, R.; Mai, D.; Bachtrog, D.

10.1101/2021.07.13.452191 — evolutionary biology — Posted on 2021-07-14

2315 Rad52 mediates class-switch DNA recombination to IgD

Xu, Y.; Zhou, H.; Post, G.; Zan, H.; Casali, P.

10.1101/2021.06.28.450246 — immunology — Posted on 2021-07-14

2316 Statistical Transfer Learning with Generative Encoding for Spatial Transcriptomics

Banh, D.

10.1101/2021.07.09.451779 — bioinformatics — Posted on 2021-07-14

2317 Whole animal modelling reveals neuronal mechanisms of decision-making and reproduces unpredictable swimming in frog tadpoles

Ferrario, A.; Palyanov, A.; Koutsikou, S.; li, w.-c.; Soffe, S.; Roberts, A.; Borisyuk, R.

10.1101/2021.07.13.452162 — bioinformatics — Posted on 2021-07-14

2318 Long-read isoform sequencing reveals tissue-specific isoform expression between active and hibernating brown bears (Ursus arctos)

Tseng, E.; Underwood, J. G.; Evans Hutzenbiler, B. D.; Trojahn, S.; Kingham, B.; Shevchenko, O.; Bernberg, E.; Robbins, C. T.; Jansen, H. T.; Kelley, J. L.

10.1101/2021.07.13.452179 — genomics — Posted on 2021-07-14

2319 Substrate, temperature, and geographical patterns among nearly 2,000 natural yeast isolates

Spurley, W. J.; Fisher, K. J.; Langdon, Q. K.; Buh, K. V.; Jarzyna, M.; Haase, M. A. B.; Sylvester, K.; Moriarty, R. V.; Rodriguez, D.; Sheddan, A.; Wright, S.; Sorlie, L.; Hulfachor, A. B.; Opulente, D. A.; Hittinger, C. T.

10.1101/2021.07.13.452236 — ecology — Posted on 2021-07-14

2320 Using wearable biosensors and ecological momentary assessments for the detection of prolonged stress in real life

Tutunji, R.; Kogias, N.; Kapteijns, B.; Krentz, M.; Krause, F.; Vassena, E.; Hermans, E.

10.1101/2021.06.29.450360 — physiology — Posted on 2021-07-14

2321 Feline tooth resorption findings from a questionnaire survey on 8115 Finnish cats and a case-control study for a more defined population drawn from the survey

Vapalahti, K.; Neittaanmäki, H.; Lohi, H.; Virtala, A.-M.

10.1101/2021.01.22.427753 — pathology — Posted on 2021-07-14

2322 A patient-driven clinicogenomic partnership through the Metastatic Prostate Cancer Project

Crowdis, J.; Balch, S.; Sterlin, L.; Thomas, B. S.; Camp, S. Y.; Dunphy, M.; Anastasio, E.; Shah, S.; Damon, A. L.; Ramos, R.; Sosa, D. M.; Small, I. K.; Tomson, B.; Nguyen, C. M.; McGillicuddy, M.; Chastain, P. S.; He, M. X.; Cheung, A. T. M.; Wankowicz, S.; Tewari, A. K.; Kim, D.; AlDubayan, S. H.; Dowdye, A.; Zola, B.; Nowak, J.; Manarite, J.; Gunn, I. H.; Olson, B.; Lander, E. S.; Painter, C. A.; Wagle, N.; Van Allen, E. M.

10.1101/2021.07.09.451849 — cancer biology — Posted on 2021-07-14

2323 Cytoplasmic Colocalization of Granulins and TDP-43 Prion-like Domain Involves Electrostatically Driven Complex Coacervation Tuned by the Redox State of Cysteines.

Bhopatkar, A. A.; Dhakal, S.; Rangachari, V.

10.1101/2021.06.25.449959 — biophysics — Posted on 2021-07-14

2324 Inulin nanostructures: The sweet-spot of carbohydrate self-assembly

Arnon, Z. A.; Grabarics, M.; Kreiser, T.; Raveh, A.; Pagel, K.; Gazit, E.

10.1101/2021.07.13.451276 — biophysics — Posted on 2021-07-14

2325 NOMA: a high-throughput microchip for robust, sequential measurements of secretions from the same single-cells

Liu, M.; Ji, Y.; Zhu, F.; Bai, X.; Li, L.; Xie, H.; Wei, Y.; Liu, X.; Luo, Y.; Liu, T.; Lin, B.; Lu, Y.

10.1101/2021.01.21.427049 — bioengineering — Posted on 2021-07-14

2326 Novel mechanistic insights into the role of Mer2 as the keystone of meiotic DNA break formation

Rousova, D.; Nivsarkar, V.; Altmannova, V.; Funk, S. K.; Raina, V. B.; Liedtke, D.; Janning, P.; Mueller, F.; Reichle, H.; Vader, G.; Weir, J. R.

10.1101/2020.07.30.228908 — biochemistry — Posted on 2021-07-14

2327 Suppressed eusocial reproduction supports evolutionary convergence over co-option

Velasque, M.; Tan, Y.; Liu, A. W.; Luscombe, N. M.; Denton, J. A.

10.1101/2021.07.11.451940 — evolutionary biology — Posted on 2021-07-14

2328 PROTEOMIC SIGNATURES OF MICROBIAL ADAPTATION TO THE HIGHEST UV -IRRADIATION ON EARTH: LESSONS FROM A SOIL ACTINOBACTERIUM

Zannier, F.; Portero, L. R.; Douki, T.; Gärtner, W.; Farias, M. E.; Albarracin, V. H.

10.1101/2021.07.11.451938 — molecular biology — Posted on 2021-07-14

2329 Synthesis of modified nucleotide polymers by the poly(U) polymerase Cid1: Application to direct RNA sequencing on nanopores.

Vo, J.; Mulroney, L.; Quick-Cleveland, J.; Jain, M.; Akeson, M.; Ares, M.

10.1101/2021.07.06.451372 — molecular biology — Posted on 2021-07-14

2330 Longitudinal changes in brain activation underlying reading fluency

Ozernov-Palchik, O.; Sury, D.; Turesky, T. K.; Yu, X.; Gaab, N.

10.1101/2021.07.09.451857 — neuroscience — Posted on 2021-07-14

2331 Local predictors of anti-Aβ therapy efficacy revealed by quantitative whole-brain microscopy

Kirschenbaum, D.; Voigt, F.; Dadgar-Kiani, E.; Catto, F.; Trevisan, C.; Bichsel, O.; Shirani, H.; Nilsson, P. K. R.; Frontzek, K.; Paganetti, P.; Helmchen, F.; Lee, J. H.; Aguzzi, A.

10.1101/2021.01.15.426090 — neuroscience — Posted on 2021-07-14

2332 An enhanced inverted encoding model for neural reconstructions

Scotti, P. S.; Chen, J.; Golomb, J. D.

10.1101/2021.05.22.445245 — neuroscience — Posted on 2021-07-14

2333 Gradient-mixing LEGO robots for purifying DNA origami nanostructures of multiple components by rate-zonal centrifugation

Sentosa, J.; Horne, B.; Djutanta, F.; Showkeir, D.; Rezvani, R.; Hariadi, R. F.

10.1101/2021.07.02.450731 — biophysics — Posted on 2021-07-14

2334 Turnover Regulation of the Rho GTPase Cdc42 by Heat Shock Protein Chaperones and the MAPK Pathway Scaffold Bem4

Cullen, P. J.; Gonzalez, B.

10.1101/2021.07.13.452164 — cell biology — Posted on 2021-07-14

2335 Single Serine on TSC2 Exerts Biased Control over mTORC1 Activation by ERK1/2 but Not Akt

Dunkerly-Eyring, B. L.; Pinilla-Vera, M.; McKoy, D.; Mishra, S.; Grajeda Martinez, M. I.; Oeing, C. U.; Ranek, M. J.; Kass, D. A.

10.1101/2021.07.13.452249 — cell biology — Posted on 2021-07-14

2336 CellProfiler 4: Improvements in Speed, Utility and Usability

Stirling, D. R.; Swain-Bowden, M. J.; Lucas, A. M.; Carpenter, A. E.; Cimini, B. A.; Goodman, A.

10.1101/2021.06.30.450416 — cell biology — Posted on 2021-07-14

2337 NSUN2-mediated m5C methylation of IRF3 mRNA negatively regulates type I interferon responses

Wang, H.; Zhang, L.; Zeng, C.; Feng, J.; Wang, D.; He, M.; Jiang, A.; Cao, Y.; Guo, X.; Liu, J.; Yan, K.; Tang, H.; Xu, K.; Fan, C.; Guo, D.; Lan, K.; Zhou, Y.; Chen, Y.

10.1101/2021.07.09.451748 — immunology — Posted on 2021-07-14

2338 Slow Cortical Waves through Cyclicity Analysis

Abraham, I.; Shahsavarani, B.; Zimmerman, B.; Husain, F.; baryshnikov, y.

10.1101/2021.05.16.444387 — neuroscience — Posted on 2021-07-14

2339 High-throughput aminoacyl-tRNA synthetase engineering for genetic code expansion in yeast

Stieglitz, J. T.; Van Deventer, J. A.

10.1101/2021.07.13.452272 — synthetic biology — Posted on 2021-07-13

2340 Citrus photosynthesis and morphology acclimate to phloem-affecting huanglongbing disease at the leaf and shoot levels

Keeley, M.; Rowland, D.; Vincent, C.

10.1101/2021.07.13.452140 — plant biology — Posted on 2021-07-14

2341 Host phenology can drive the evolution of intermediate virulence strategies in some obligate-killer parasites

MacDonald, H.; Akcay, E.; Brisson, D.

10.1101/2021.03.13.435259 — evolutionary biology — Posted on 2021-07-13

2342 Morphological integration during postnatal ontogeny: implications for evolutionary biology

Hubbe, A.; Garcia, G.; Sebastiao, H.; Porto, A.; Machado, F. A.; Cheverud, J.; Marroig, G.

10.1101/2021.07.13.452198 — developmental biology — Posted on 2021-07-13

2343 Functional peroxisomes are required for heat shock-induced hormesis in Caenorhabditis elegans

Musa, M.; Milosevic, I.; Raimundo, N.; Krisko, A.

10.1101/2021.07.13.452156 — cell biology — Posted on 2021-07-14

2344 ATP-Independent Nucleosome Unfolding by FACT: Electron Microscopy Analysis

Sivkina, A. L.; Karlova, M. G.; Valieva, M. E.; McCullough, L.; Formosa, T.; Shaytan, A. K.; Feofanov, A. V.; Kirpichnikov, M. P.; Sokolova, O. S.; Studitsky, V. M.

10.1101/2021.07.13.452273 — molecular biology — Posted on 2021-07-13

2345 Imaging and single cell sequencing analyses of super-enhancer activation mediated by NF-κB in B cells

Wibisana, J. N.; Inaba, T.; Shinohara, H.; Yumoto, N.; Hayashi, T.; Umeda, M.; Ebisawa, M.; Nikaido, I.; Sako, Y.; Okada, M.

10.1101/2021.07.13.452147 — molecular biology — Posted on 2021-07-13

2346 Disentangling environmental effects in microbial association networks

Deutschmann, I. M.; Lima-Mendez, G.; Krabberod, A. K.; Raes, J.; Vallina, S. M.; Faust, K.; Logares, R.

10.1101/2021.07.13.452182 — microbiology — Posted on 2021-07-13

2347 Searching for Consistent Brain Network Topologies Across the Garden of (Shortest) Forking Paths

Luppi, A. I.; Gellersen, H. M.; Peattie, A. R. D.; Manktelow, A. E.; Menon, D.; Dimitriadis, S. I.; Stamatakis, E. A.

10.1101/2021.07.13.452257 — neuroscience — Posted on 2021-07-13

2348 MSA Transformer

Rao, R. M.; Liu, J.; Verkuil, R.; Meier, J.; Canny, J.; Abbeel, P.; Sercu, T.; Rives, A.

10.1101/2021.02.12.430858 — synthetic biology — Posted on 2021-07-13

2349 PDF Data Extractor (PDE) - A Free Web Application and R Package Allowing the Extraction of Tables from Portable Document Format (PDF) Files and High-Throughput Keyword Searches of Full-Text Articles

Stricker, E.; Scheurer, M. E.

10.1101/2021.07.13.452159 — scientific communication and education — Posted on 2021-07-13

2350 Structural insight into the dual function of LbpB in mediating Neisserial pathogenesis

Noinaj, N.; Yadav, R.; Govindan, S.; Daczkowski, C.; Mesecar, A.; Chakravarthy, S.

10.1101/2021.07.13.452223 — biophysics — Posted on 2021-07-13

2351 Analysis of the mechanism of Aldo-keto reductase dependent cis-platin resistance in HepG2 based on transcriptomic and NADH metabolic analysis

Sun, T.; Gao, L.; Sun, X.; Wang, X.; Guo, R.; Yu, Y.

10.1101/2021.04.29.441897 — biophysics — Posted on 2021-07-13

2352 Differentiation of Peritubular Myoid-Like Cells from Human Induced Pluripotent Stem Cells

Robinson, M. A.; Witherspoon, L.; Willerth, S.; Flannigan, R.

10.1101/2021.06.04.447123 — bioengineering — Posted on 2021-07-13

2353 Divergence in dimerization and activity of primate APOBEC3C

Gaba, A.; Hix, M. A.; Suhail, S.; Flath, B.; Boysan, B.; Williams, D. R.; Pelletier, T.; Emerman, M.; Morcos, F.; Cisneros, G. A.; Chelico, L.

10.1101/2021.07.13.452235 — biochemistry — Posted on 2021-07-13

2354 Climate and mountains shaped human ancestral genetic lineages

Maisano Delser, P.; Krapp, M.; Beyer, R.; Jones, E.; Miller, E. F.; Hovhannisyan, A.; Parker, M.; Siska, V.; Vizzari, M. T.; Pearmain, E. J.; Imaz-Rosshandler, I.; Leonardi, M.; Somma, G. L.; Hodgson, J.; Tysall, E.; Xue, Z.; Cassidy, L.; Bradley, D. G.; Eriksson, A.; Manica, A.

10.1101/2021.07.13.452067 — genomics — Posted on 2021-07-13

2355 Towards a Comprehensive Variation Benchmark for Challenging Medically-Relevant Autosomal Genes

Wagner, J.; Olson, N. D.; Harris, L.; McDaniel, J.; Cheng, H.; Fungtammasan, A.; Hwang, Y.-C.; Gupta, R.; Wenger, A. M.; Rowell, W. J.; Khan, Z. M.; Farek, J.; Zhu, Y.; Pisupati, A.; Mahmoud, M.; Xiao, C.; Yoo, B.; Sahraeian, S. M. E.; Miller, D. E.; Jaspez, D.; Lorenzo-Salazar, J. M.; Munoz-Barrera, A.; Rubio-Rodriguez, L. A.; Flores, C.; Narzisi, G.; Evani, U. S.; Clarke, W. E.; Lee, J.; Mason, C. E.; Lincoln, S. E.; Miga, K. H.; Ebbert, M. T.; Shumate, A.; Li, H.; Chin, C.-S.; Zook, J. M.; Sedlazeck, F. J.

10.1101/2021.06.07.444885 — genomics — Posted on 2021-07-13

2356 Experimental evidence that metapopulation structure can accelerate adaptive evolution

Chakraborty, P. P.; Nemzer, L. R.; Kassen, R.

10.1101/2021.07.13.452242 — evolutionary biology — Posted on 2021-07-13

2357 Life history traits and dispersal shape neutral genetic diversity in metapopulations

Garnier, J.; Lafontaine, P.

10.1101/2021.07.13.452195 — ecology — Posted on 2021-07-13

2358 G protein-coupled receptor signaling regulates ER-mitochondria contacts

Lim, Y.; Cho, I.-T.; Rennke, H. G.; Cho, G.

10.1101/2020.05.11.088815 — cell biology — Posted on 2021-07-13

2359 Leishmania major formins are cytosolic actin bundler play an important role in cell physiology

Kushwaha, R.; Seth, A.; AS, J.; Dileep, D.; PB, R.; Datta, R.; MAITI, S.

10.1101/2021.04.12.439584 — cell biology — Posted on 2021-07-13

2360 Chromosome-level genome assembly of a human fungal pathogen reveals synteny among geographically distinct species

Voorhies, M.; Cohen, S.; Shea, T. P.; Petrus, S.; Munoz, J. F.; Poplawski, S.; Goldman, W. E.; Michael, T. P.; Cuomo, C. A.; Sil, A.; Beyhan, S.

10.1101/2021.07.13.452254 — microbiology — Posted on 2021-07-13

2361 Direct and indirect cues can enable dual-adaptation, but through different learning processes

Forano, M.; Schween, R.; Taylor, J. A.; Hegele, M.; Franklin, D. W.

10.1101/2021.04.09.439164 — neuroscience — Posted on 2021-07-13

2362 Individual believes about temporal continuity explain perceptual biases

Glasauer, S.; Shi, Z.

10.1101/2021.07.13.452167 — neuroscience — Posted on 2021-07-13

2363 Glutamatergic and GABAergic neurons mediate distinct neurodevelopmental phenotypes of STXBP1 encephalopathy

Kim, J. H.; Chen, W.; Chao, E. S.; Chen, H.; Xue, M.

10.1101/2021.07.13.452234 — neuroscience — Posted on 2021-07-13

2364 Transcriptomic changes highly similar to Alzheimer's disease are observed in a subpopulation of individuals during normal brain aging

Peng, S.; Zeng, L.; Haure-mirande, J.-v.; Wang, M.; Huffman, D. M.; Haroutunian, V.; Ehrlich, M.; Zhang, B.; Tu, Z.

10.1101/2021.06.01.446628 — neuroscience — Posted on 2021-07-13

2365 Metabolic resilience is encoded in genome plasticity

Agudelo, L. Z.; Tuyeras, R. V.; Llinares, C.; Morcuende, A.; Park, Y.; Sun, N.; Kuosmanen, S. M.; Atabaki-Pasdar, N.; Ho, L.-L.; Galani, K.; Franks, P. W.; Kutlu, B.; Grove, K.; Femenia, T.; Kellis, M.

10.1101/2021.06.25.449953 — systems biology — Posted on 2021-07-13

2366 A Plasmid System with Tunable Copy Number

Rouches, M. V.; Xu, Y.; Cortes, L.; Lambert, G.

10.1101/2021.07.13.451660 — synthetic biology — Posted on 2021-07-13

2367 Unique Features of Different Classes of G-Protein-Coupled Receptors Revealed from Sequence Coevolutionary and Structural Analysis

Do, H.; Haldane, A.; Levy, R.; Miao, Y.

10.1101/2021.06.03.446974 — bioinformatics — Posted on 2021-07-13

2368 Ribovore: ribosomal RNA sequence analysis for GenBank submissions and database curation

Schäffer, A. A.; McVeigh, R.; Robbertse, B.; Schoch, C. L.; Johnston, A.; Underwood, B. A.; Karsch-Mizrachi, I.; Nawrocki, E. P.

10.1101/2021.02.11.430762 — bioinformatics — Posted on 2021-07-13

2369 A Xeno-free Media for the In Vitro Expansion of Human Spermatogonial Stem Cells

Robinson, M. A.; Witherspoon, L.; Willerth, S.; Flannigan, R.

10.1101/2021.06.04.447118 — bioengineering — Posted on 2021-07-13

2370 A Novel Organoid Model of In Vitro Spermatogenesis Using Human Induced Pluripotent Stem Cells

Robinson, M. A.; Witherspoon, L.; Willerth, S.; Flannigan, R.

10.1101/2021.06.04.447122 — bioengineering — Posted on 2021-07-13

2371 De novo macrocyclic peptides for inhibiting, stabilising and probing the function of the Retromer endosomal trafficking complex

10.1101/2020.12.03.410779 — biochemistry — Posted on 2021-07-13

2372 Novel mechanistic insights into the role of Mer2 as the keystone of meiotic DNA break formation

Rousova, D.; Nivsarkar, V.; Altmannova, V.; Funk, S. K.; Raina, V. B.; Liedtke, D.; Janning, P.; Mueller, F.; Reichle, H.; Vader, G.; Weir, J. R.

10.1101/2020.07.30.228908 — biochemistry — Posted on 2021-07-13

2373 Effects of Perinatal Fluoxetine Exposure on Novelty-induced Social and Non-Social Investigation Behaviors in a Seminatural Environment

Sylte, O. C.; Johansen, J. S.; Heinla, I.; Houwing, D. J.; Olivier, J. D.; Heijkoop, R.; Snoeren, E. M.

10.1101/2021.02.09.430401 — animal behavior and cognition — Posted on 2021-07-13

2374 Megapixel camera arrays for high-resolution animal tracking in multiwell plates

Barlow, I.; Feriani, L.; Minga, E.; McDermott-Rouse, A.; O'Brien, T.; Liu, Z.; Hofbauer, M.; Stowers, J. R.; Andersen, E.; Ding, S. S.; Brown, A. E.

10.1101/2021.04.16.440222 — animal behavior and cognition — Posted on 2021-07-13

2375 Optimized Cas9 expression improves performance of large-scale CRISPR screening

Fernandes Neto, J. M.; Jastrzebski, K.; Lieftink, C.; Krenning, L.; Dias, M.; Morris, B.; van der Ven, D.; Heimans, H.; Medema, R. H.; Bernards, R.; Beijersbergen, R. L.

10.1101/2021.07.13.452178 — genomics — Posted on 2021-07-13

2376 The quantitative genetics of the prevalence of infectious diseases: hidden genetic variation due to Indirect Genetic Effects dominates heritable variation and response to selection

Bijma, P.; Hulst, D.; de Jong, M. C.

10.1101/2021.04.07.438789 — genetics — Posted on 2021-07-13

2377 A Floxed exon (Flexon) approach to Cre-mediated conditional gene expression

Shaffer, J. M.; Greenwald, I.

10.1101/2021.07.13.452276 — genetics — Posted on 2021-07-13

2378 Plexin-A2 Promotes The Proliferation And The Development Of Tumors From Glioblastoma Derived Cells

Neufeld, G.; Toledano, S.; Sabag, A. D.; Liburkin-Dan, T.; Kessler, O.

10.1101/2021.07.12.452132 — cell biology — Posted on 2021-07-13

2379 Myonuclear maturation dynamics in aged and adult regenerating mouse skeletal muscle

Kurland, J. V.; Deusen, A. V.; Pawlikowski, B.; Hall, M.; Betta, N. D.; Antwine, T.; Cutler, A. A.; Russell, A.; Allen, M. A.; Dowell, R. D.; Olwin, B. B.

10.1101/2021.07.13.452218 — molecular biology — Posted on 2021-07-13

2380 Co-translational assembly counteracts promiscuous interactions

Seidel, M.; Becker, A.; Pereira, F.; Landry, J. J. M.; Trevisan Doimo de Azevedo, N.; Fusco, C. M.; Kaindl, E.; Baumbach, J.; Langer, J. D.; Schuman, E. M.; Patil, K. R.; Hummer, G.; Benes, V.; Beck, M.

10.1101/2021.07.13.452229 — molecular biology — Posted on 2021-07-13

2381 Host-symbiont population genomics provide insights into partner fidelity, transmission mode and habitat adaptation in deep-sea hydrothermal vent snails

Breusing, C.; Genetti, M.; Russell, S.; Corbett-Detig, R.; Beinart, R.

10.1101/2021.07.13.452231 — molecular biology — Posted on 2021-07-13

2382 The Bardet-Biedl protein Bbs1 controls photoreceptor outer segment protein and lipid composition

Masek, M.; Etard, C.; Hofmann, C.; Huelsmeier, A.; Zang, J.; Takamiya, M.; Gesemann, M.; Neuhauss, S. C.; Hornemann, T.; Straehle, U.; Bachmann-Gagescu, R.

10.1101/2021.07.13.452166 — molecular biology — Posted on 2021-07-13

2383 Gene-Specific Nonsense-Mediated mRNA Decay Targeting for Cystic Fibrosis Therapy

Kim, Y. J.; Nomakuchi, T.; Papaleonidopoulou, F.; Krainer, A. R.

10.1101/2021.07.13.452144 — molecular biology — Posted on 2021-07-13

2384 Bacterial microcompartments for isethionate desulfonation in the taurine-degrading human-gut bacterium Bilophila wadsworthia

Burrichter, A. G.; Doerr, S.; Bergmann, P.; Haiss, S.; Keller, A.; Fournier, C.; Franchini, P.; Isono, E.; Schleheck, D.

10.1101/2021.07.13.451622 — microbiology — Posted on 2021-07-13

2385 A genetic toolkit for investigating Clavibacter: markerless deletion, permissive site identification and an integrative plasmid

Stevens, D.; Tang, A.; Coaker, G.

10.1101/2021.07.13.452269 — microbiology — Posted on 2021-07-13

2386 The Burkholderia cenocepacia type VI secretion system effector TecA is a virulence factor during lung infection

Loeven, N. A.; Perault, A. I.; Cotter, P. A.; Hodges, C. A.; Schwartzman, J. D.; Hampton, T. H.; Bliska, J. B.

10.1101/2021.07.13.451912 — microbiology — Posted on 2021-07-13

2387 Metabolic regulation of ILC2 differentiation into ILC1-like cells during Mycobacterium tuberculosis infection

Hudrisier, D.; Corral, D.; Charton, A.; Krauss, M. Z.; Blanquart, E.; Levillain, F.; Lefrancais, E.; Sneperger, T.; Girard, J.-P.; Eberl, G.; Poquet, Y.; Guery, J.-C.; Arguello, R. J.; Hepworth, M. R.; Neyrolles, O.

10.1101/2021.01.19.427257 — immunology — Posted on 2021-07-13

2388 Dopamine influences attentional rate modulation in Macaque posterior parietal cortex

van Kempen, J.; Brandt, C.; Distler, C.; Bellgrove, M.; Thiele, A.

10.1101/2020.05.15.097675 — neuroscience — Posted on 2021-07-13

2389 Gauging the capacity for concurrent motor planning in human fMRI with information constraints in bounded rational decision-making models

Schach, S.; Lindner, A.; Braun, D. A.

10.1101/2021.07.13.452019 — neuroscience — Posted on 2021-07-13

2390 The role of reading experience in atypical cortical tracking of speech and speech-in-noise in dyslexia

Destoky, F.; Bertels, J.; Niesen, M.; Wens, V.; Vander Ghinst, M.; Rovai, A.; Trotta, N.; Lallier, M.; De Tiege, X.; Bourguignon, M.

10.1101/2021.07.13.452155 — neuroscience — Posted on 2021-07-13

2391 Prediction Errors Disrupt Hippocampal Representations and Update Episodic Memories

Sinclair, A. H.; Manalili, G. M.; Brunec, I. K.; Adcock, R. A.; Barense, M. D.

10.1101/2020.09.29.319418 — neuroscience — Posted on 2021-07-13

2392 The neurocomputational architecture of explore-exploit decision making

Hogeveen, J.; Mullins, T. S.; Romero, J.; Eversole, E.; Rogge-Obando, K.; Mayer, A. R.; Costa, V. D.

10.1101/2021.06.21.449128 — neuroscience — Posted on 2021-07-13

2393 Perceiving and remembering speech depend on multifractal nonlinearity in movements producing and exploring speech

Bloomfield, L.; Lane, E.; Mangalam, M.; Kelty-Stephen, D.

10.1101/2021.03.28.437328 — neuroscience — Posted on 2021-07-13

2394 Interaction between SARS-CoV-2 spike glycoprotein and human skin models: a molecular dynamics study

Domingo, M.; Faraudo, J.

10.1101/2021.07.13.452154 — biophysics — Posted on 2021-07-13

2395 CloneSig can jointly infer intra-tumor heterogeneity and mutational signature activity in bulk tumor sequencing data

Abecassis, J.; Reyal, F.; Vert, J.-P.

10.1101/825778 — bioinformatics — Posted on 2021-07-13

2396 MetaFetcheR: An R package for complete mapping of small compound data

A. Yones, S.; Csombordi, R.; Komorowski, J.; Diamanti, K.

10.1101/2021.02.28.433248 — bioinformatics — Posted on 2021-07-13

2397 Electronic "photoreceptors" enable prosthetic vision with acuity matching the natural resolution in rats

Wang, B.-Y.; Chen, Z. C.; Bhuckory, M.; Huang, T. W.; Shin, A.; Zuckerman, V.; Ho, E.; Rosenfeld, E.; Galambos, L.; Kamins, T.; Mathieson, K.; Palanker, D.

10.1101/2021.07.12.452093 — bioengineering — Posted on 2021-07-13

2398 Bioelectricity generation from live marine photosynthetic macroalgae

Shlosberg, Y.; Krupnik, N.; Toth, T. N.; Eichenbaum, B.; Meirovich, M.; Meiri, D.; Yehezkeli, O.; Schuster, G.; Israel, A.; Adir, N.

10.1101/2021.04.16.440133 — bioengineering — Posted on 2021-07-13

2399 Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3.1 reveal a novel binding site for positive modulators

Botte, M.; Huber, S.; Bucher, D.; Klint, J. K.; Rodriguez, D.; Tagmose, L.; Chami, M.; Cheng, R. K. Y.; Hennig, M.; Abdul Rahman, W.

10.1101/2021.07.13.452180 — biochemistry — Posted on 2021-07-13

2400 Calorie Restriction Maintains Mitochondrial Function and Redox Balance Avoiding Lipidomic Reprogramming during Isoproterenol-Induced Cardiac Hypertrophy

David, C. E. B.; Lucas, A. M. B.; Cunha, P. L. O.; Viana, Y. I. P.; Yoshinaga, M. Y.; Miyamoto, S.; Chaves Filho, A. B.; Kowaltowski, A. J.; Facundo, H. T.

10.1101/2021.07.13.452233 — biochemistry — Posted on 2021-07-13

2401 Conformational dynamics during misincorporation and mismatch extension defined using a DNA polymerase with a fluorescent artificial amino acid

Dangerfield, T. L.; Kirmizialtin, S.; Johnson, K. A.

10.1101/2021.07.13.452224 — biochemistry — Posted on 2021-07-13

2402 Predicting protein domain temperature adaptation across the prokaryote-eukaryote divide

Jensen, S. E.; Johnson, L. C.; Casstevens, T.; Buckler, E. S.

10.1101/2021.07.13.452245 — molecular biology — Posted on 2021-07-13

2403 Disentangling temporal associations in marine microbial networks

Deutschmann, I. M.; Krabberod, A. K.; Benites, L. F.; Latorre, F.; Delage, E.; Marrase, C.; Balague, V.; Gasol, J. M.; Massana, R.; Eveillard, D.; Chaffron, S.; Logares, R.

10.1101/2021.07.13.452187 — microbiology — Posted on 2021-07-13

2404 Specific phenotypic, genomic, and fitness evolutionary trajectories toward antibiotic resistance induced by pesticide co-stressors in Escherichia coli

Xing, Y.; Kang, X.; Zhang, S.; Men, Y.

10.1101/2021.07.13.452255 — microbiology — Posted on 2021-07-13

2405 VirB4- and VirD4-like ATPases, components of a putative type 4C secretion system in Clostridioides difficile

Sorokina, J.; Sokolova, I.; Rybolovlev, I.; Shevlyagina, N.; Troitskiy, V.; Zhukhovitsky, V. G.; Belyi, Y.

10.1101/2021.07.12.452133 — microbiology — Posted on 2021-07-13

2406 Fifteen shades of clay: distinct microbial community profiles obtained from bentonite samples by cultivation and direct nucleic acid extraction

Vachon, M. A.; Engel, K.; Beaver, R. C.; Slater, G. W.; Binns, J.; Neufeld, J. D.

10.1101/2021.07.13.452221 — microbiology — Posted on 2021-07-13

2407 A global dataset of seaweed net primary productivity

Pessarrodona, A.; Filbee-Dexter, K.; Krumhansl, K. A.; Moore, P. J.; Wernberg, T.

10.1101/2021.07.12.452112 — ecology — Posted on 2021-07-13

2408 Electrophysiological correlates of proactive and reactive inhibition in a modified visual Go/NoGo task

Kuty, J.; Damborska, A.; Linhartova, P.; Martin, L.; Jerabkova, B.; Rudisinova, D.; Bares, M.; Kasparek, T.

10.1101/2021.07.12.451610 — neuroscience — Posted on 2021-07-13

2409 2',3'-cAMP treatment mimics abiotic stress response

Chodasiewicz, M.; Kerber, O.; Gorka, M.; Moreno Beltran, J. C.; Sampathkumar, A.; Skirycz, A.

10.1101/2021.07.12.452129 — plant biology — Posted on 2021-07-13

2410 In vitro determinants of e-cig aerosol condensate bioavailability and toxicity: Influence of cell culture parameters and utility of a normalized dose metric in e-cig studies

Obodo, U. C.; O'Connor, T. R.

10.1101/2021.07.12.452101 — pharmacology and toxicology — Posted on 2021-07-13

2411 Single-cell multi-omic analysis of thymocyte development reveals NFAT as adriver of CD4/CD8 lineage commitment

Steier, Z.; McIntyre, L. L.; Lutes, L. K.; Huang, T.-S.; Robey, E. A.; Yosef, N.; Streets, A.

10.1101/2021.07.12.452119 — bioinformatics — Posted on 2021-07-13

2412 Designing Interpretable Convolution-Based Hybrid Networks for Genomics

Ghotra, R. S.; Lee, N. K.; Tripathy, R.; Koo, P. K.

10.1101/2021.07.13.452181 — bioinformatics — Posted on 2021-07-13

2413 Tree-based automated machine learning to predict biogas production for anaerobic co-digestion of organic waste

Wang, Y.; Huntington, T.; Scown, C. D.

10.1101/2021.07.12.452124 — bioinformatics — Posted on 2021-07-13

2414 Core bone diameter in an organic implant-less technique affecting the biomechanical properties of the anterior cruciate ligament fixation; an in-vitro study

Mohseni, M.; Nourani, A.; Korani, H.; Moeinnia, H.; Borjali, A.; Ghias, N.; Chizari, M.

10.1101/2021.07.12.452098 — bioengineering — Posted on 2021-07-13

2415 Protozoan predation drives adaptive divergence in Pseudomonas fluorescens SBW25; ecology meets experimental evolution.

Golzar, F. S.; Ferguson, G. C.; Hendrickson, H. L.

10.1101/2021.07.12.452127 — evolutionary biology — Posted on 2021-07-13

2416 Genetic, bioacoustic and morphological analyses reveal cryptic speciation in the warbling vireo complex (Vireo gilvus: Vireonidae: Passeriformes)

Carpenter, A. M.; Graham, B. A.; Spellman, G. M.; Klicka, J.; Burg, T. M.

10.1101/2021.07.12.452121 — evolutionary biology — Posted on 2021-07-13

2417 Predictions of biodiversity are improved by integrating trait-based competition with abiotic filtering

Chalmandrier, L.; Stouffer, D. B.; Purcell, A. S. T.; Lee, W. G.; Tanentzap, A. J.; Laughlin, D. C.

10.1101/2021.07.12.448750 — ecology — Posted on 2021-07-13

2418 A phage parasite deploys a nicking nuclease effector to inhibit replication of its viral host

LeGault, K.; Barth, Z.; DePaola, P.; Seed, K.

10.1101/2021.07.12.452122 — microbiology — Posted on 2021-07-13

2419 Detecting the state of drowsiness induced by propofol by spatial filter and machine learning algorithm on EEG recording

Zhou, Z.; Srinivasan, R.

10.1101/2021.07.12.452077 — neuroscience — Posted on 2021-07-13

2420 Bidirectionally connected cores in a mouse connectome: Towards extracting the brain subnetworks essential for consciousness

Kitazono, J.; Aoki, Y.; Oizumi, M.

10.1101/2021.07.12.452022 — neuroscience — Posted on 2021-07-13

2421 Multiplex base editing to convert TAG into TAA codons in the human genome

Chen, Y.; Hysolli, E.; Chen, A.; Casper, S.; Liu, S.; Yang, K.; Liu, C.; Church, G.

10.1101/2021.07.13.452007 — synthetic biology — Posted on 2021-07-13

2422 Analysis of amino acid change dynamics reveals SARS-CoV-2 variant emergence

Bernasconi, A.; Mari, L.; Casagrandi, R.; Ceri, S.

10.1101/2021.07.12.452076 — bioinformatics — Posted on 2021-07-13

2423 A drug candidate for treating adverse reactions caused by pathogenic antibodies inducible by COVID-19 virus and vaccines

Wang, H.; Wu, X.; Zhang, Y.; Chen, Q.; Dai, L.; Chen, Y.; Liu, X.

10.1101/2021.07.13.452194 — microbiology — Posted on 2021-07-13

2424 Development Of The Inactivated QazCovid-In Vaccine: Protective Efficacy Of The Vaccine In Syrian Hamsters

Zhugunissov, K.; Zakarya, K.; Khairullin, B.; Orynbayev, M.; Abduraimov, Y.; Kassenov, M.; Sultankulova, K.; Kerimbayev, A.; Nurabayev, S.; Myrzhakhmetova, B.; Nakhanov, A.; Nurpeisova, A.; Chervyakova, O.; Assanzhanova, N.; Burashev, Y.; Mambetaliev, M.; Azanbekova, M.; Kopeyev, S.; Kozhabergenov, N.; Issabek, A.; Tuyskanova, M.; Kutumbetov, L.

10.1101/2021.07.13.452175 — immunology — Posted on 2021-07-13

2425 Probing remdesivir nucleotide analogue insertion to SARS-CoV-2 RNA dependent RNA polymerase in viral replication

Romero, M. E.; Long, C.; La Rocco, D.; Keerthi, A. M.; Xu, D.; Yu, J.

10.1101/2021.07.12.452099 — biophysics — Posted on 2021-07-13

2426 Immunogenicity and pre-clinical efficacy of an OMV-based SARS-CoV-2 vaccine

Grandi, A.; Tomasi, M.; Accordini, S.; Bertelli, C.; Vanzo, T.; Gagliardi, A.; Caproni, E.; Tamburini, S.; Fantappie, L.; Di Lascio, G.; Bisoffi, Z.; Piubelli, C.; Valenti, M. T.; Dalle Carbonare, L.; Zipeto, D.; Rava, M.; Fumagalli, V.; Di Lucia, P.; Marotta, D.; Sala, E.; Iannacone, M.; Cherepanov, P.; Bolognesi, M.; Pizzato, M.; Grandi, G.

10.1101/2021.07.12.452027 — immunology — Posted on 2021-07-13

2427 TNF-α levels in respiratory samples are associated with SARS-CoV-2 infection.

Pereson, M. J.; Badano, M. N.; Aloisi, N.; Chuit, R.; Braco, M. M.; Bare, P.

10.1101/2021.07.12.452071 — immunology — Posted on 2021-07-13

2428 In situ imaging of bacterial membrane projections and associated protein complexes using electron cryo-tomography

Kaplan, M.; Chreifi, G.; Metskas, L. A.; Liedtke, J.; Wood, C. R.; Oikonomou, C. M.; NICOLAS, W. J.; Subramanian, P.; Zacharoff, L. A.; Wang, Y.; Chang, Y.-W.; Beeby, M.; Dobro, M.; Mcbride, M. J.; Briegel, A.; Shaffer, C.; Jensen, G. J.

10.1101/2021.07.13.452161 — molecular biology — Posted on 2021-07-13

2429 Structural insight into Marburg virus nucleoprotein-RNA complex formation

Fujita-Fujiharu, Y.; Sugita, Y.; Takamatsu, Y.; Houri, K.; Igarashi, M.; Muramoto, Y.; Nakano, M.; Tsunoda, Y.; Becker, S.; Noda, T.

10.1101/2021.07.13.452116 — microbiology — Posted on 2021-07-13

2430 GH18 family glycoside hydrolase Chitinase A of Salmonella facilitates bacterial invasion and survival by modulating host immune responses

Chandra, K.; Chakravortty, D.

10.1101/2021.07.13.452150 — microbiology — Posted on 2021-07-13

2431 An atlas of the Norway spruce needle seasonal transcriptome

Bag, P.; Lihavainen, J.; Delhomme, N.; Riquelme, T.; Robinson, K. M.; Jansson, S.

10.1101/2021.07.12.452085 — plant biology — Posted on 2021-07-13

2432 Inulin nanostructures: The sweet-spot of carbohydrate self-assembly

Arnon, Z. A.; Grabarics, M.; Kreiser, T.; Raveh, A.; Pagel, K.; Gazit, E.

10.1101/2021.07.13.451276 — biophysics — Posted on 2021-07-13

2433 Long chain lipids facilitate insertion of large nanoparticles into membranes of small unilamellar vesicles

Marzouq, A.; Morgenstein, L.; Yudovich, S.; Atkins, A.; Grupi, A.; Weiss, S.

10.1101/2021.07.12.452073 — biophysics — Posted on 2021-07-13

2434 How drugs modulate the performance of the human heart

Peirlinck, M.; Yao, J.; Sahli Costabal, F.; Kuhl, E.

10.1101/2021.07.12.452066 — biophysics — Posted on 2021-07-13

2435 Development of photo-lenalidomide for cellular target identification

Lin, Z.; Amako, Y.; Kabir, F.; Flaxman, H. A.; Budnik, B.; Woo, C. M.

10.1101/2021.07.12.452075 — biochemistry — Posted on 2021-07-13

2436 Complete genomic and epigenetic maps of human centromeres

Altemose, N.; Logsdon, G.; Bzikadze, A. V.; Sidhwani, P.; Langley, S. A.; Caldas, G. V.; Hoyt, S. J.; Uralsky, L.; Ryabov, F. D.; Shew, C.; Sauria, M. E. G.; Borchers, M.; Gershman, A.; Mikheenko, A.; Shepelev, V. A.; Dvorkina, T.; Kunyavskaya, O.; Vollger, M. R.; Rhie, A.; McCartney, A. M.; Asri, M.; Lorig-Roach, R.; Shafin, K.; Aganezov, S.; Olson, D.; Gomes de Lima, L.; Potapova, T.; Hartley, G. A.; Haukness, M.; Kerpedjiev, P.; Gusev, F.; Tigyi, K.; Brooks, S. Y.; Young, A.; Nurk, S.; Koren, S.; Salama, S.; Paten, B.; Rogaev, E. I.; Streets, A. M.; Karpen, G. H.; Dernburg, A.; Sullivan, B.

10.1101/2021.07.12.452052 — genomics — Posted on 2021-07-13

2437 A complete reference genome improves analysis of human genetic variation

Aganezov, S.; Yan, S. M.; Soto, D. C.; Kirsche, M.; Zarate, S.; Avdeyev, P.; Taylor, D. J.; Shafin, K.; Shumate, A.; Xiao, C.; Wagner, J.; McDaniel, J.; Olson, N. D.; Sauria, M. E. G.; Vollger, M. R.; Rhie, A.; Meredith, M.; Martin, S.; Lee, J.; Koren, S.; Rosenfeld, J.; Paten, B.; Layer, R.; Chin, C.-S.; Sedlazeck, F. J.; Hansen, N. F.; Miller, D. E.; Phillippy, A. M.; Miga, K. H.; McCoy, R. C.; Dennis, M. Y.; Zook, J. M.; Schatz, M. C.

10.1101/2021.07.12.452063 — genomics — Posted on 2021-07-13

2438 Prolonged morphological expansion of spiny-rayed fishes following the end-Cretaceous

Ghezelayagh, A.; Harrington, R. C.; Burress, E. D.; Campbell, M. A.; Buckner, J. C.; Chakrabarty, P.; Glass, J. R.; McCraney, W. T.; Unmack, P. J.; Thacker, C. E.; Alfaro, M. E.; Friedman, S. T.; Ludt, W. D.; Cowman, P. F.; Friedman, M.; Price, S. A.; Dornburg, A.; Faircloth, B. C.; Wainwright, P. C.; Near, T. J.

10.1101/2021.07.12.452083 — evolutionary biology — Posted on 2021-07-13

2439 VCP protects neurons from proteopathic seeding

Zhu, J.; Pittman, S.; Dhavale, D.; French, R.; Patterson, J. N.; Kaleelurrrahuman, S.; Sun, Y.; Buchser, W.; Bieschke, J.; Kotzbauer, P.; Ayala, Y. M.; Davis, A. A.; Weihl, C. C.

10.1101/2021.07.12.452081 — neuroscience — Posted on 2021-07-13

2440 Single-nucleus sequencing reveals enriched expression of genetic risk factors sensitises Motor Neurons to degeneration in ALS

Limone, F.; Mordes, D.; Couto, A.; Pietilainen, O.; Joseph, B.; Burberry, A.; Ghosh, S. D.; Meyer, D.; Goldman, M.; Bortolin, L.; Cobos, I.; Therrien, M.; Stevens, B.; Kadiu, I.; McCarroll, S. A.; Eggan, K.

10.1101/2021.07.12.452054 — neuroscience — Posted on 2021-07-13

2441 Arousal impacts distributed hubs modulating the integration of brain functional connectivity

Lee, K.; Horien, C.; O'Connor, D.; Garand-Sheridan, B.; Tokoglu, F.; Scheinost, D.; Lake, E. M.; Constable, R. T.

10.1101/2021.07.12.452041 — neuroscience — Posted on 2021-07-13

2442 Electrocorticography based monitoring of anaesthetic depth in mice

Schmidt, D.; English, G.; Gent, T.; Yanik, M. F.; von der Behrens, W.

10.1101/2021.07.12.452032 — neuroscience — Posted on 2021-07-13

2443 Pharmacokinetics of caffeine: A systematic analysis of reported data for application in metabolic phenotyping and liver function testing

Grzegorzewski, J.; Bartsch, F.; Köller, A.; König, M.

10.1101/2021.07.12.452094 — pharmacology and toxicology — Posted on 2021-07-13

2444 Determining molecular archetype composition and expression from bulk tissues with unsupervised deconvolution

Wu, C.-T.; Chen, L.; Herrington, D.; Shen, M.; Yu, G.; Clarke, R.; Liu, C.; Wang, Y.

10.1101/2021.07.12.452047 — bioinformatics — Posted on 2021-07-13

2445 Zinc2+ ion inhibits SARS-CoV-2 main protease and viral replication in vitro.

Panchariya, L.; Khan, W. A.; Kuila, S.; Sonkar, K.; Sahoo, S.; Ghoshal, A.; Kumar, A.; Verma, D. K.; Hasan, A.; Das, S.; Thakur, J. K.; Halder, R.; Sunil, S.; Arulandu, A.

10.1101/2021.06.15.448551 — biochemistry — Posted on 2021-07-13

2446 WDR82-binding long non-coding RNA lncEry controls mouse erythroid differentiation and maturation

Yang, S.; Sun, G.; Wu, P.; Cong, C.; Kuang, Y.; Zheng, Z.; He, Y.; Gu, Q.; Lu, T.; Zhu, C.; Wang, F.; Gou, F.; Yang, Z.; Zhao, X.; Yuan, S.; Yang, L.; Lu, S.; Li, Y.; Lv, X.; Dong, F.; Ma, Y.; Yu, J.; Ng, L. G.; Shi, L.; Liu, J.; Cheng, H.; Cheng, T.

10.1101/2021.07.13.452142 — cell biology — Posted on 2021-07-13

2447 Solar simulated ultraviolet radiation inactivates HCoV-NL63 and SARS-CoV-2 coronaviruses at environmentally relevant doses

Wondrak, G. T.; Jandova, J.; Williams, S. J.; Schenten, D.

10.1101/2021.06.25.449831 — microbiology — Posted on 2021-07-13

2448 Explainable multi-view framework for dissecting inter-cellular signaling from highly multiplexed spatial data

Tanevski, J.; Ramirez Flores, R. O.; Gabor, A.; Schapiro, D.; Saez-Rodriguez, J.

10.1101/2020.05.08.084145 — systems biology — Posted on 2021-07-13

2449 ChronoRoot: High-throughput phenotyping by deep segmentation networks reveals novel temporal parameters of plant root system architecture

Gaggion, N.; Ariel, F.; Daric, V.; Lambert, E.; Legendre, S.; Roule, T.; Camoirano, A.; Milone, D. H.; Crespi, M.; Blein, T.; Ferrante, E.

10.1101/2020.10.27.350553 — plant biology — Posted on 2021-07-13

2450 Accessibility Over Transposable Elements Reveals Genetic Determinants of Stemness Properties in Normal and Leukemic Hematopoiesis

Nadorp, B.; Grillo, G.; Qamra, A.; Mitchell, A.; Arlidge, C.; Takayama, N.; Murison, A.; Tonekaboni, S. A. M.; Arruda, A.; Wang, J.; Minden, M.; Dick, J.; Lupien, M.

10.1101/2021.02.16.431334 — cancer biology — Posted on 2021-07-13

2451 A daily-updated database and tools for comprehensive SARS-CoV-2 mutation-annotated trees

McBroome, J.; Thornlow, B.; Hinrichs, A. S.; De Maio, N.; Goldman, N.; Haussler, D.; Corbett-Detig, R.; Turakhia, Y.

10.1101/2021.04.03.438321 — bioinformatics — Posted on 2021-07-13

2452 Positive selection and enhancer evolution shaped lifespan and body mass in great apes

Tejada-Martinez, D.; Avelar, R. A.; Lopes, I.; Zhang, B.; Novoa, G.; de Magalhaes, J. P.; Trizzino, M.

10.1101/2021.07.08.451631 — genomics — Posted on 2021-07-13

2453 Modelling complex population structure using F-statistics and Principal Component Analysis

Peter, B. M.

10.1101/2021.07.13.452141 — evolutionary biology — Posted on 2021-07-13

2454 The glycolysis regulator PFKFB4 interacts with ICMT and activates RAS/AKT signaling-dependent cell migration in melanoma.

Sittewelle, M.; Kappes, V.; Lecuyer, D.; Monsoro-Burq, A. H.

10.1101/2020.03.23.004119 — cell biology — Posted on 2021-07-13

2455 Myosin-driven Nucleation of Actin Filaments Drives Stereocilia Development Critical for Hearing

Moreland, Z. G.; Jiang, F.; Aguilar, C.; Barzik, M.; Gong, R.; Shams, A.; Faaborg-Andersen, C.; Werth, J. C.; Harley, R.; Sutton, D. C.; Cole, S. M.; Parker, A.; Morse, S.; Wilson, E.; Takagi, Y.; Sellers, J. R.; Brown, S. D.; Friedman, T. B.; Alushin, G. M.; Bowl, M. R.; Bird, J. E.

10.1101/2021.07.09.451618 — cell biology — Posted on 2021-07-13

2456 UPF3A and UPF3B are redundant and modular activators of nonsense-mediated mRNA decay in human cells

Wallmeroth, D.; Boehm, V.; Lackmann, J.-W.; Altmueller, J.; Dieterich, C.; Gehring, N. H.

10.1101/2021.07.07.451444 — molecular biology — Posted on 2021-07-13

2457 Linker histone dH1K27 dimethylation marks Drosophila heterochromatin independently of H3K9 methylation

Bernues, J.; Izquierdo-Boulstridge, A.; Reina Garcia, O.; Castejon, L.; Fernandez-Castaner, E.; Leal, N.; Guerrero-Pepinosa, N.; Bonet-Costa, C.; Vujatovic, O.; Azorin, F.

10.1101/2021.06.22.449135 — molecular biology — Posted on 2021-07-13

2458 Substrate traits govern the assembly of microbial community engaged in metabolic division of labor

Wang, M.; Chen, X.; Tang, Y.-Q.; Nie, Y.; Wu, X.-L.

10.1101/2020.11.18.387787 — microbiology — Posted on 2021-07-13

2459 Highly diverse flavobacterial phages as mortality factor during North Sea spring blooms

Bartlau, N.; Wichels, A.; Krohne, G.; Adriaenssens, E. M.; Heins, A.; Fuchs, B. M.; Amann, R.; Moraru, C.

10.1101/2021.05.20.444936 — microbiology — Posted on 2021-07-13

2460 Identification of novel translated small ORFs in Escherichia coli using complementary ribosome profiling approaches

Stringer, A. M.; Smith, C.; Mangano, K.; Wade, J. T.

10.1101/2021.07.02.450978 — microbiology — Posted on 2021-07-13

2461 Interactions between sensory prediction error and task error during implicit motor learning

Tsay, J.; Haith, A.; Ivry, R. B.; Kim, H. E.

10.1101/2021.06.20.449180 — neuroscience — Posted on 2021-07-13

2462 Linguistic modulation of the neural encoding of phonemes

Kim, S.-G.; De Martino, F.; Overath, T.

10.1101/2021.07.05.451175 — neuroscience — Posted on 2021-07-13

2463 In vivo evidence that SORL1, encoding the endosomal recycling receptor SORLA, can function as a causal gene in Alzheimer's Disease

Andersen, O. M.; Boegh, N.; Landau, A. M.; Ploeen, G. G.; Jensen, A. M. G.; Monti, G.; Ulhoei, B. P.; Nyengaard, J. R.; Jacobsen, K. R.; Joergensen, M. M.; Holm, I. E.; Kristensen, M. L.; Hansen, E. S.; Teunissen, C. E.; Breidenbach, L.; Droescher, M.; Liu, Y.; Pedersen, H. S.; Callesen, H.; Luo, Y.; Bolund, L.; Brooks, D. J.; Laustsen, C.; Small, S. A.; Mikkelsen, L. F.; Soerensen, C. B.

10.1101/2021.07.13.452149 — neuroscience — Posted on 2021-07-13

2464 Comparison of mouse models reveals a molecular distinction between psychotic illness in PWS and schizophrenia

Zahova, S.; Humby, T.; Davies, J.; Morgan, J.; Isles, A.

10.1101/2021.01.26.428232 — neuroscience — Posted on 2021-07-13

2465 Dysregulated myogenesis and autophagy in genetically induced pulmonary emphysema

Balnis, J.; Drake, L. A.; Singer, D. V.; Vincent, C.; Korponay, T. C.; D'Armiento, J. M.; Lee, C. G.; Elias, J. A.; Singer, H. A.; Jaitovich, A.

10.1101/2021.07.08.450201 — physiology — Posted on 2021-07-13

2466 LISA: Learned Indexes for Sequence Analysis

Ho, D.; Kalikar, S.; Misra, S.; Ding, J.; Md, V.; Tatbul, N.; Li, H.; Kraska, T.

10.1101/2020.12.22.423964 — bioinformatics — Posted on 2021-07-13

2467 Clipper: p-value-free FDR control on high-throughput data from two conditions

Ge, X.; Chen, Y. E.; Song, D.; McDermott, M.; Woyshner, K.; Manousopoulou, A.; Wang, N.; Li, W.; Wang, L. D.; Li, J. J.

10.1101/2020.11.19.390773 — bioinformatics — Posted on 2021-07-13

2468 Linking rhizosphere processes across scales: Opinion

Schnepf, A.; Carminati, A.; Ahmed, M.; Ani, M.; Benard, P.; Bentz, J.; Bonkowski, M.; Brax, M.; Diehl, D.; Duddek, P.; Kroener, E.; Javaux, M.; Landl, M.; Lehndorff, E.; Lippold, E.; Lieu, A.; Mueller, C. W.; Oburger, E.; Otten, W.; Portell-Canal, X.; Phalempin, M.; Prechtel, A.; Schulz, R.; Vanderborght, J.; Vetterlein, D.

10.1101/2021.07.08.451655 — bioengineering — Posted on 2021-07-13

2469 Low cell number proteomic analysis using in-cell protease digests reveals a robust signature for cell cycle state classification

Kelly, V.; al-Rawi, A. S.; Lewis, D. A.; Kustatscher, G.; Ly, T.

10.1101/2020.07.03.186023 — biochemistry — Posted on 2021-07-13

2470 Biochemical and structural studies of target lectin SapL1 from the emerging opportunistic microfungus Scedosporium apiospermum

Martinez-Alarcon, D.; Balloy, V.; Bouchara, J.-P.; Pieters, R. J.; VARROT, A.

10.1101/2020.11.10.376251 — biochemistry — Posted on 2021-07-13

2471 Intraflagellar transport-A deficiency attenuates ADPKD in a renal tubular- and maturation-dependent manner

Wang, W.; Silva, L.; Wang, H.; Kavanaugh, M. A.; Pottorf, T.; Allard, B.; Jacobs, D.; Dong, R.; Cornelius, J.; Chaturvedi, A.; Pritchard, M.; Sharma, M.; Slawson, C.; Wallace, D.; Calvet, J.; Tran, P.

10.1101/2020.04.26.061796 — genetics — Posted on 2021-07-13

2472 Multivariate genome-wide association study on tissue-sensitive diffusion metrics identifies key molecular pathways for axonal growth, synaptogenesis, and astrocyte-mediated neuroinflammation

Fan, C. C.; Loughnan, R.; Pechva, D.; Chen, C.-H.; Hagler, D.; Thompson, W. K.; Parker, N.; van der Meer, D.; Frei, O.; Andreassen, O.; Dale, A. M.

10.1101/2021.06.24.449723 — genetics — Posted on 2021-07-13

2473 Gradual Compaction of the Central Spindle Decreases its Dynamicity as Revealed in PRC1 and EB1 Gene-Edited Human Cells

Asthana, J.; Cade, N. I.; Normanno, D.; Lim, W. M.; Surrey, T.

10.1101/2020.07.09.195347 — cell biology — Posted on 2021-07-13

2474 Mammalian UPF3A and UPF3B activate NMD independently of their EJC binding

Yi, Z.; Arvola, R. M.; Myers, S.; Dilsavor, C. N.; Abu Alhasan, R.; Carter, B. N.; Patton, R. D.; Bundschuh, R.; Singh, G.

10.1101/2021.07.02.450872 — molecular biology — Posted on 2021-07-13

2475 Decoding representations of discriminatory and hedonic information during appetitive and aversive touch

Kryklywy, J.; Ehlers, M. R.; Beukers, A. O.; Moore, S. R.; Todd, R.; Anderson, A. K.

10.1101/2020.09.24.310383 — neuroscience — Posted on 2021-07-13

2476 Assessing Overall Reproducibility for Large-scale High-throughput MRI-based Association Studies

Jiao, Z.; Lai, Y.; Kang, J.; Gong, W.; Ma, L.; Jia, T.; Xie, C.; Cheng, W.; Heinz, A.; Desrivieres, S.; Schumann, G.; Sun, F.; Feng, J.

10.1101/2020.08.18.253740 — neuroscience — Posted on 2021-07-13

2477 The use of high-resolution computed tomography to explore age-related trabecular change in human ribs

Mavroudas, S.; Dominguez, V. M.

10.1101/2021.07.12.452053 — cell biology — Posted on 2021-07-12

2478 Human engineered skeletal muscle of hypaxial origin from pluripotent stem cells with advanced function and regenerative capacity

Shahriyari, M.; Islam, M.; Sakib, M.; Rika, A.; Krueger, D.; Kaurani, L.; Anandakumar, H.; Shomroni, O.; Schmidt, M.; Salinas, G.; Unger, A.; Linke, W.; Zschuentzsch, J.; Schmidt, J.; Fischer, A.; Zimmermann, W.; Tiburcy, M.

10.1101/2021.07.12.452030 — cell biology — Posted on 2021-07-12

2479 Lack of blocking activity in anti-CTLA-4 antibodies reduces toxicity, but not anti-tumor efficacy

Stone, E. L.; Carter, K. P.; Wagner, E. K.; Asensio, M. A.; Benzie, E.; Chiang, Y. Y.; Coles, G. L.; Edgar, C.; Gautam, B. K.; Gras, A.; Leong, J.; Leong, R.; Manickam, V. A.; Mizrahi, R. A.; Niedecken, A.; Saini, J.; Sandhu, S. K.; Simons, J. F.; Stadtmiller, K.; Tinsley, B.; Tracy, L.; Wayham, N. P.; Lim, Y. W.; Adler, A. A.; Johnson, D. S.

10.1101/2021.07.12.452090 — immunology — Posted on 2021-07-12

2480 Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

Bell, E. S.; Shah, P.; Zuela - Sopilniak, N.; Kim, D.; McGregor, A. L.; Isermann, P.; Davidson, P.; Elacqua, J. J.; Lakins, J.; Vahdat, L.; Weaver, V.; Smolka, M. B.; Span, P.; Lammerding, J.

10.1101/2021.07.12.451842 — cancer biology — Posted on 2021-07-12

2481 Therapeutic base and prime editing of COL7A1 mutations in recessive dystrophic epidermolysis bullosa

Hong, S.-a.; Kim, S.-E.; Lee, A.-y.; Hwang, G.-h.; Kim, J. H.; Iwata, H.; Kim, S.-C.; Bae, S.; Lee, S. E.

10.1101/2021.07.12.452037 — bioengineering — Posted on 2021-07-12

2482 miR-9a regulates levels of both rhomboid mRNA and protein in the early Drosophila melanogaster embryo

Gallicchio, L.; Griffiths-Jones, S.; Ronshaugen, M.

10.1101/2021.07.12.452096 — developmental biology — Posted on 2021-07-12

2483 Newly Emergent Apelin Expressing Endothelial Stem-like Cells Orchestrate Lung Microvascular Repair

Godoy, R. S.; Cook, D. P.; Cober, N. D.; Deng, Y.; Wang, L.; Chakravarti, A.; Rowe, K.; Stewart, D. J.

10.1101/2021.07.12.452061 — cell biology — Posted on 2021-07-12

2484 A comparison of wild and captive Comal Springs riffle beetle (Heterelmis comalensis) microbiomes

Mays, Z.; Carlos-Shanley, C.; Campbell, L. G.; Hunter, A.

10.1101/2021.07.12.452104 — microbiology — Posted on 2021-07-12

2485 An intestinally secreted host factor limits bacterial colonization but promotes microsporidia invasion of C. elegans

El Jarkass, H. T.; Mok, C.; Schertzberg, M. R.; Fraser, A. G.; Troemel, E. R.; Reinke, A. W.

10.1101/2021.07.12.452088 — microbiology — Posted on 2021-07-12

2486 IgG surface mobility promotes antibody-dependent cellular phagocytosis by Syk and Arp2/3 mediated reorganization of Fcγ receptors in macrophages.

Jo, S.; Cronin, N. M.; Nurmalasari, N. P. D.; Kerkvleit, J. G.; Bailey, E. M.; Scott, B. L.; Hoppe, A. D.

10.1101/2021.07.12.451665 — immunology — Posted on 2021-07-12

2487 Flight-tone mediated circadian control of audibility in mating swarms of Anopheles mosquitoes

Somers, J.; Georgiades, M.; Su, M. P.; Bagi, J.; Andres, M.; Mills, G.; Ntabaliba, W.; Moore, S. J.; Spaccapelo, R.; Albert, J. T.

10.1101/2021.07.12.452033 — neuroscience — Posted on 2021-07-12

2488 A sex chromosome drives the emergence of vocal learning following hormonal manipulation in female zebra finches

Davenport, M.; Choe, H. N.; Matsunami, H.; Jarvis, E. D.

10.1101/2021.07.12.452102 — neuroscience — Posted on 2021-07-12

2489 TOR signalling is required for host lipid metabolic remodelling and survival following enteric infection in Drosophila

Deshpande, R. S.; Lee, B.; Qiao, Y.; Grewal, S. S.

10.1101/2021.07.12.452110 — physiology — Posted on 2021-07-12

2490 Behavioral effects of ethanol in the Red Swamp Crayfish (Procambarus clarkii)

Gutierrez, A.; Creehan, K. M.; de Guglielmo, G.; Roberts, A. J. A.; Taffe, M. A.

10.1101/2021.06.05.447220 — pharmacology and toxicology — Posted on 2021-07-12

2491 Interpretable machine learning models for single-cell ChIP-seq imputation

Albrecht, S.; Andreani, T.; Andrade-Navarro, M. A.; Fontaine, J.-F.

10.1101/2019.12.20.883983 — bioinformatics — Posted on 2021-07-12

2492 How fragile we are. Influence of STimulator of INterferon Genes, STING, variants on pathogen recognition and immune response efficiency

Morere, J.; Hognon, C.; Miclot, T.; Jiang, T.; Dumont, E.; Barone, G.; Bignon, E.; MONARI, A.

10.1101/2021.07.12.452045 — biochemistry — Posted on 2021-07-12

2493 Gains and Losses Affect Learning Differentially at Low and High Attentional Load

Banaie Boroujeni, K.; Watson, M. R.; Womelsdorf, T.

10.1101/2020.09.01.278168 — animal behavior and cognition — Posted on 2021-07-12

2494 The spatial landscape of clonal somatic mutations in benign and malignant tissue

Erickson, A.; Berglund, E.; He, M.; Marklund, M.; Mirzazadeh, R.; Schultz, N.; Bergenstrahle, L.; Kvastad, L.; Andersson, A.; Bergenstrahle, J.; Larsson, L.; Shamikh, A.; Basmaci, E.; de Stahl, T. D.; Rajakumar, T.; Thrane, K.; Ji, A. L.; Khavari, P. A.; Tarish, F.; Tanoglidi, A.; Maaskola, J.; Colling, R.; Mirtti, T.; Hamdy, F. C.; Woodcock, D. J.; Helleday, T.; Mills, I. G.; Lamb, A. D.; Lundeberg, J.

10.1101/2021.07.12.452018 — genomics — Posted on 2021-07-12

2495 Coalescent-based species delimitation meets deep learning: Insights from a highly fragmented cactus system

Perez, M. F.; Bonatelli, I. A.; Romeiro-Brito, M.; Franco, F. F.; Taylor, N. P.; Zappi, D. C.; Moraes, E. M.

10.1101/2020.12.23.424219 — evolutionary biology — Posted on 2021-07-12

2496 Natural variation in copper tolerance in Drosophila melanogaster is shaped by transcriptional and physiological changes in the gut

Green, L.; Radio, S. E.; Rech, G.; Salces-Ortiz, J.; Gonzalez, J.

10.1101/2021.07.12.452058 — evolutionary biology — Posted on 2021-07-12

2497 C25-modified rifamycin derivatives with improved activity against Mycobacterium abscessus

Paulowski, L.; Beckham, K. S. H.; Johansen, M. D.; Berneking, L.; Van, N.; Degefu, Y.; Staack, S.; Vasquez Sotomayor, F.; Asar, L.; Rohde, H.; Aldridge, B. B.; Aepfelbacher, M.; Parret, A.; Wilmanns, M.; Kremer, L.; Combrink, K.; Maurer, F. P.

10.1101/2021.07.12.452042 — microbiology — Posted on 2021-07-12

2498 Macrophages stimulate epicardial VEGFaa expression to trigger cardiomyocyte proliferation in larval zebrafish heart regeneration

Bruton, F. A.; Kaveh, A.; Ross-Stewart, K.; Matrone, G.; Oremek, M. E.; Solomonidis, E. G.; Tucker, C. S.; Mullins, J. J.; Brittan, M.; Taylor, J. M.; Rossi, A. G.; Denvir, M. A.

10.1101/2021.06.15.448575 — immunology — Posted on 2021-07-12

2499 Attention and prediction modulations in expected and unexpected visuospatial trajectories.

Baker, K. S.; Pegna, A. J.; Yamamoto, N.; Johnston, P.

10.1101/2020.11.10.376368 — neuroscience — Posted on 2021-07-12

2500 A connectivity-constrained computational account of topographic organization in primate high-level visual cortex

Blauch, N. M.; Behrmann, M.; Plaut, D.

10.1101/2021.05.29.446297 — neuroscience — Posted on 2021-07-12

2501 GWAS-associated variants, non-genetic factors, and transient transcriptome in Multiple Sclerosis etiopathogenesis: a colocalization analysis

Umeton, R.; Bellucci, G.; Bigi, R.; Romano, S.; Buscarinu, M. C.; Renie', R.; Rinaldi, V.; Pizzolato Umeton, R.; Morena, E.; Romano, C.; Mechelli, R.; Salvetti, M.; Ristori, G.

10.1101/2021.03.12.434773 — neuroscience — Posted on 2021-07-12

2502 A coupled mechano-biochemical framework for root meristem morphogenesis

Marconi, M.; Gallemi, M.; Benkova, E.; Wabnik, K.

10.1101/2021.01.27.428294 — plant biology — Posted on 2021-07-12

2503 A Proteome-scale Analysis of Vertebrate Protein Amino Acid Occurrence: Thermoadaptation shows a Correlation with Protein Solvation but less so with Dynamics

LI, Z.; Buck, M.

10.1101/2020.08.10.244558 — biophysics — Posted on 2021-07-12

2504 Molecular insights into the μ-opioid receptorselective signaling

Sounier, R.; Granier, S.; Maurel, D.; Cong, X.; DEMENE, H.; Saint-Paul, J.; Peysson, F.; Vasiliauskaite-Brooks, I.; Hagelberger, J.; Golebiowski, J.

10.1101/2021.03.22.436421 — bioinformatics — Posted on 2021-07-12

2505 Long-read error correction: a survey and qualitative comparison

Morisse, P.; Lecroq, T.; Lefebvre, A.

10.1101/2020.03.06.977975 — bioinformatics — Posted on 2021-07-12

2506 Impedance scaling for gold and platinum microelectrodes

Fan, B.; Wolfrum, B.; Robinson, J.

10.1101/2021.03.09.434678 — bioengineering — Posted on 2021-07-12

2507 Variation in upstream open reading frames contributes to allelic diversity in protein abundance

Gage, J. L.; Mali, S.; McLoughlin, F.; Khaipho-Burch, M.; Monier, B.; Bailey-Serres, J.; Vierstra, R. D.; Buckler, E. S.

10.1101/2021.05.25.445499 — genomics — Posted on 2021-07-12

2508 Allele frequency divergence reveals ubiquitous influence of positive selection in Drosophila

Bertram, J.

10.1101/2021.03.15.435474 — evolutionary biology — Posted on 2021-07-12

2509 Semi-continuous propagation of influenza A virus and its defective interfering particles: analyzing the dynamic competition to select candidates for antiviral therapy

Pelz, L.; Ruediger, D.; Dogra, T.; Alnaji, F. G.; Genzel, Y.; Brooke, C. B.; Kupke, S. Y.; Reichl, U.

10.1101/2021.02.08.430251 — evolutionary biology — Posted on 2021-07-12

2510 Autogenous and anautogenous Culex pipiens bioforms exhibit insulin-like peptide signaling pathway gene expression differences that are not dependent upon larval nutrition

Cheatle Jarvela, A. M.; Bell, K.; Noreuil, A.; Fritz, M.

10.1101/2021.06.20.449144 — evolutionary biology — Posted on 2021-07-12

2511 Direct Antimicrobial Resistance Prediction from clinical MALDI-TOF mass spectra using Machine Learning

Weis, C.; Cuenod, A.; Rieck, B.; Llinares-Lopez, F.; Dubuis, O.; Graf, S.; Lang, C.; Oberle, M.; Brackmann, M.; Soegaard, K. K.; Osthoff, M.; Borgwardt, K.; Egli, A.

10.1101/2020.07.30.228411 — microbiology — Posted on 2021-07-12

2512 PKR-mediated Stress Response Enhances Dengue and Zika Virus Replication

Ricciardi-Jorge, T.; Lummertz da Rocha, E.; Gonzalez-Kozlova, E.; Rodrigues-Luiz, G. F.; Ferguson, B. J.; Irigoyen, N.; Mansur, D. S.

10.1101/2021.04.08.439069 — immunology — Posted on 2021-07-12

2513 How we pay attention in naturalistic visual search settings

Turoman, N.; Tivadar, R.; Retsa, C.; Murray, M. M.; Matusz, P. J.

10.1101/2020.07.30.229617 — neuroscience — Posted on 2021-07-12

2514 Causal neural mechanisms of context-based object recognition

Wischnewski, M.; Peelen, M. V.

10.1101/2021.04.23.441170 — neuroscience — Posted on 2021-07-12

2515 Neuroligin-mediated neurodevelopmental defects are induced by mitochondrial dysfunction and prevented by lutein in C. elegans

Maglioni, S.; Schiavi, A.; Melcher, M.; Brinkmann, V.; Luo, Z.; Raimundo, N.; Laromaine, A.; Meyer, J.; Distelmaier, F.; Ventura, N.

10.1101/2020.02.20.957225 — neuroscience — Posted on 2021-07-12

2516 Matrix Inversion and Subset Selection (MISS): A novel pipeline for quantitative mapping of diverse cell types across the murine brain

Mezias, C.; Torok, J.; Maia, P.; Markley, E.; Raj, A.

10.1101/833566 — neuroscience — Posted on 2021-07-12

2517 Brain virtual histology with X-ray phase-contrast tomography Part I: whole-brain myelin mapping in white-matter injury models

Chourrout, M.; Rositi, H.; Ong, E.; Hubert, V.; Paccalet, A.; Foucault, L.; Autret, A.; Fayard, B.; Olivier, C.; Bolbos, R.; Peyrin, F.; Crola Da Silva, C.; Meyronet, D.; Raineteau, O.; Elleaume, H.; Brun, E.; Chauveau, F.; Wiart, M.

10.1101/2021.03.24.436852 — neuroscience — Posted on 2021-07-12

2518 Outlier detection in multimodal MRI identifies rare individual phenotypes among 20,000 brains

Ma, Z.; Reich, D. S.; Dembling, S.; Duyn, J. H.; Koretsky, A. P.

10.1101/2021.05.10.441017 — neuroscience — Posted on 2021-07-12

2519 Maternal RND3/RhoE deficiency impairs placental mitochondrial function in preeclampsia by modulating PPARγ-UCP2 cascade

Huang, L.; Ma, Y.; Chen, L.; Chang, J.; Zhong, M.; Wang, Z.; Sun, Y.; Chen, X.; Sun, F.; Xiao, L.; Chen, J.; Lai, Y.; Yan, C.; Yue, X.

10.1101/2020.06.22.164921 — pathology — Posted on 2021-07-12

2520 AltumAge: A Pan-Tissue DNA-Methylation Epigenetic Clock Based on Deep Learning

Paulo de Lima Camillo, L.; Lapierre, L. R.; Singh, R.

10.1101/2021.06.01.446559 — bioinformatics — Posted on 2021-07-12

2521 Differential fate of acellular vascular scaffolds in vivo involves macrophages and T-cell subsets

Banerjee, D.; Nayakawde, N. B.; Antony, D.; Deshmukh, M.; Ghosh, S.; Sihlbom, C.; Berger, E.; Ul Haq, U.; Olausson, M.

10.1101/2020.11.21.392654 — bioengineering — Posted on 2021-07-12

2522 Strong attraction of male mosquitoes (Aedes aegypti) to humans

Amos, B. A.; Hoffmann, A. A.; Staunton, K. M.; Lau, M.-J.; Burkot, T. R.; Ross, P. A.

10.1101/2021.05.24.445527 — animal behavior and cognition — Posted on 2021-07-12

2523 Mistreating birth-death models as priors in phylogenetic analysis compromises our ability to compare models

May, M. R.; Rothfels, C.

10.1101/2021.07.12.452074 — evolutionary biology — Posted on 2021-07-12

2524 Scanning mutagenesis of RNA-binding protein ProQ reveals a quality control role for the Lon protease

El Mouali, Y.; Ponath, F.; Scharrer, V.; Wenner, N.; Hinton, J. C. D.; Vogel, J.

10.1101/2021.07.12.452043 — microbiology — Posted on 2021-07-12

2525 Cell adhesion factors during adolescence support amygdalo-cortical connections and flexible action later in life

Kietzman, H. W.; Shapiro, L. P.; Guo, J.; Trinoskey-Rice, G.; Gourley, S. L.

10.1101/2021.07.12.452062 — neuroscience — Posted on 2021-07-12

2526 Drug-free nasal spray as a barrier against SARS-CoV-2 infection: safety and efficacy in human nasal airway epithelia

Fais, F.; Juskeviciene, R.; Francardo, V.; Mateos, S.; Constant, S.; Borelli, M.; Hohenfeld, I. P.; Meyer, T.

10.1101/2021.07.12.452021 — pharmacology and toxicology — Posted on 2021-07-12

2527 Paleoecological implications of Lower-Middle Triassic stromatolites and microbe-metazoan build-ups in the Germanic Basin: Insights into the aftermath of the Permian - Triassic crisis

Pei, Y.; Hagdorn, H.; Voigt, T.; Duda, J.-P.; Reitner, J.

10.1101/2021.07.12.452070 — paleontology — Posted on 2021-07-12

2528 High throughput and affordable genome-wide methylation profiling of circulating cell-free DNA by Methylated DNA sequencing (MeD-seq) of LpnPI digested fragments

Deger, T.; Boers, R. G.; de Weerd, V.; Angus, L.; van der Put, M. M.; Boers, J. B.; Azmani, Z.; van IJcken, W.; Grunhagen, D. J.; van Dessel, L. F.; Lolkema, M. P.; Verhoef, C.; Sleijfer, S.; Martens, J. W.; Gribnau, J.; Wilting, S. M.

10.1101/2021.07.12.452012 — genomics — Posted on 2021-07-12

2529 Zic1 advances epaxial myotome morphogenesis to cover the neural tube via Wnt11r

Heilig, A. K.; Nakamura, R.; Shimada, A.; Hashimoto, Y.; Nakamura, Y.; Wittbrodt, J.; Takeda, H.; Kawanishi, T.

10.1101/2021.07.12.452069 — developmental biology — Posted on 2021-07-12

2530 Substrate recognition determinants of human eIF2α phosphatases

Hodgson, G.; Andreeva, A.; Bertolotti, A.

10.1101/2021.07.12.452048 — cell biology — Posted on 2021-07-12

2531 Proteome-wide quantitative RNA interactome capture (qRIC) identifies phosphorylation sites with regulatory potential in RBM20

Vieira-Vieira, C. H.; Dauksaite, V.; Gotthardt, M.; Selbach, M.

10.1101/2021.07.12.452044 — cell biology — Posted on 2021-07-12

2532 In situ solid-liquid extraction enhances recovery of taxadiene from engineered S. cerevisiae cell factories

Santoyo-Garcia, J.; Walls, L.; Nowrouzi, B.; Ochoa-Villareal, M.; Loake, G.; Dimartino, S.; Rios-Solis, L.

10.1101/2021.07.12.452013 — bioengineering — Posted on 2021-07-12

2533 Cultural behaviours can be experimentally induced in wild baboons despite constraints on social information transmission

Carter, A.; Cowlishaw, G.

10.1101/2021.07.12.452028 — animal behavior and cognition — Posted on 2021-07-12

2534 From telomere to telomere: the transcriptional and epigenetic state of human repeat elements

Hoyt, S. J.; Storer, J. M.; Hartley, G. A.; Grady, P. G. S.; Gershman, A.; de Lima, L. G.; Limouse, C.; Halabian, R.; Wojenski, L.; Rodriguez, M.; Altemose, N.; Core, L.; Gerton, J. L.; Makalowski, W.; Olson, D.; Rosen, J.; Smit, A. F. A.; Straight, A. F.; Vollger, M. R.; Wheeler, T.; Schatz, M.; Eichler, E.; Phillippy, A. M.; Timp, W.; Miga, K. H.; O'Neill, R. J.

10.1101/2021.07.12.451456 — genomics — Posted on 2021-07-12

2535 The transcription factor Xrp1 orchestrates both reduced translation and cell competition upon defective ribosome assembly or function

Kiparaki, M.; Khan, C.; Folgado Marco, V.; Chuen, J.; Baker, N. E.

10.1101/2021.07.12.452023 — developmental biology — Posted on 2021-07-12

2536 Novel insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis.

Uehara, Y.; Nikolaidis, N. M.; Pitstick, L. B.; Wu, H.; Yu, J. J.; Zhang, E.; Hasegawa, Y.; Tanaka, Y.; Noel, J. G.; Gardner, J. C.; Kopras, E. J.; Haffey, W. D.; Greis, K. D.; Guo, J.; Woods, J. C.; Wikenheiser-Brokamp, K. A.; Zhao, S.; Xu, Y.; Kyle, J. E.; Ansong, C.; Teitelbaum, S. L.; Inoue, Y.; Altinisik, G.; McCormack, F. X.

10.1101/2021.07.11.451970 — molecular biology — Posted on 2021-07-12

2537 Novel strains of Klebsiella africana and Klebsiella pneumoniae in Australian Fruit Bats (Pteropus poliocephalus)

McDougall, F. K.; Wyres, K. L.; Judd, L. M.; Boardman, W. S. J.; Holt, K. E.; Power, M. L.

10.1101/2021.07.12.451971 — microbiology — Posted on 2021-07-12

2538 Pooled screening of CAR T cells identifies non-native signaling domains for next- generation immunotherapies

Goodman, D. B.; Azimi, C. S.; Kearns, K.; Garakani, K.; Garcia, J.; Patel, N.; Hwang, B.; Lee, D.; Park, E.; Ye, C. J.; Marson, A.; Bluestone, J.; Roybal, K.

10.1101/2021.07.11.451980 — immunology — Posted on 2021-07-12

2539 Age-related differences in encoding-retrieval similarity and their relationship to false memory

Chamberlain, J. D.; Bowman, C. R.; Dennis, N. A.

10.1101/2021.07.12.451838 — neuroscience — Posted on 2021-07-12

2540 Custom-made design of metabolite composition in N. benthamiana leaves using CRISPR activators.

Selma, S.; Sanmartin, N.; Espinosa-Ruiz, A.; Gianoglio, S.; Lopez-Gresa, M. P.; Vazquez-Vilar, M.; Flors, V.; Granell, A.; Orzaez, D.

10.1101/2021.07.12.452005 — synthetic biology — Posted on 2021-07-12

2541 Multiplex viral tropism assay in complex cell populations with single-cell resolution

Keng, C. T.; Guo, K.; Lim, D. S.; Chew, W. L.

10.1101/2021.07.12.451549 — synthetic biology — Posted on 2021-07-12

2542 Parallel Framework for Inferring Genome-Scale Gene Regulatory Networks

Sebastian, S.; Roy, S.

10.1101/2021.07.11.451988 — bioinformatics — Posted on 2021-07-12

2543 Isonicotinamide extends yeast chronological lifespan through a mechanism that diminishes nucleotides

Kalita, A.; Hesles, E. E.; Power, L. N.; Wang, D.; singh, P. K.; Smith, J. S.

10.1101/2021.07.11.451986 — biochemistry — Posted on 2021-07-12

2544 Cooperative escape in ants and robots

Srinivasa Gopalakrishnan, G. P.; Mandal, S.; Giardina, F.; Kennedy, J.; Murthy, V. N.; Mahadevan, L.

10.1101/2021.07.12.451633 — animal behavior and cognition — Posted on 2021-07-12

2545 Genomic and transcriptomic analyses of the subterranean termite Reticulitermes speratus: gene duplication facilitates social evolution

Shigenobu, S.; Hayashi, Y.; Watanabe, D.; Tokuda, G.; Hojo, M. Y.; Toga, K.; Saiki, R.; Yaguchi, H.; Masuoka, Y.; Suzuki, R.; Suzuki, S.; Kimura, M.; Matsunami, M.; Sugime, Y.; Oguchi, K.; Niimi, T.; Gotoh, H.; Hojo, M. K.; Miyazaki, S.; Toyoda, A.; Miura, T.; Maekawa, K.

10.1101/2021.07.11.451559 — genomics — Posted on 2021-07-12

2546 Interspecific gene flow and vicariance in Northern African rear-edge white oak populations revealed by joint analysis of microsatellites and flanking sequences.

Olivier, L.; Aissi, A.; Vela, E.; Beghami, Y.

10.1101/2021.07.12.452011 — evolutionary biology — Posted on 2021-07-12

2547 Rapid shifts in mitochondrial tRNA import in a plant lineage with extensive mitochondrial tRNA gene loss

Warren, J. M.; Salinas-Giege, T.; Triant, D. A.; Taylor, D. R.; Drouard, L.; Sloan, D. B.

10.1101/2021.07.12.451983 — evolutionary biology — Posted on 2021-07-12

2548 Genome mosaicism in field strains of Mycoplasma bovis as footprints of in-host horizontal chromosomal transfer

Garcia-Galan, A.; Baranowski, E.; Hygonenq, M.-C.; Walch, M.; Croville, G.; Citti, C.; De la Fe, C.; Nouvel, L.-X.

10.1101/2021.07.12.452010 — evolutionary biology — Posted on 2021-07-12

2549 Mutation rate and spectrum in Caenorhabditis elegans mutation accumulation lines subjected to RNAi-induced knockdown of the mismatch repair gene msh-2

Katju, V.; Konrad, A.; Deiss, T. C.; Bergthorsson, U.

10.1101/2021.07.12.452034 — evolutionary biology — Posted on 2021-07-12

2550 Are marine biodiversity hotspots still blackspots for barcoding?

Mugnai, F.; Meglecz, E.; CoMBoMed group, ; Costantini, F.

10.1101/2021.07.12.448298 — ecology — Posted on 2021-07-12

2551 Sex-specific association between urinary kisspeptin and pubertal development

de Freitas, R. S.; Franca, T. F. A.; Pompeia, S.

10.1101/2021.07.12.452029 — developmental biology — Posted on 2021-07-12

2552 Cellular remodeling and JAK inhibition promote zygotic gene expression in the Ciona germline

Ohta, N.; Christiaen, L.

10.1101/2021.07.12.452040 — developmental biology — Posted on 2021-07-12

2553 PPARdelta signaling activation improves metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes.

Wickramasinghe, N. M.; Sachs, D.; Shewale, B.; Gonzalez, D. M.; Dhanan-Krishnan, P.; Torre, D.; LaMarca, E.; Raimo, S.; Dariolli, R.; Serasinghe, M.; Mayourian, J.; Sebra, R.; Beaumont, K. G.; Iyengar, R.; French, D. L.; Hansen, A.; Eschenhagen, T.; Chipuk, J. E.; Sobie, E. A.; Jacobs, A.; Akbarian, S.; Ischiropoulos, H.; Ma'ayan, A.; Houten, S.; Costa, K.; Dubois, N. C.

10.1101/2021.07.12.451352 — cell biology — Posted on 2021-07-12

2554 Creating a bottleneck: Robust LC3B lipidation analysis by adjusting autophagic flux with low concentrations of Bafilomycin A1

Liebl, M. P.; Meister, S. C.; Frey, L.; Hendrich, K.; Klemmer, A.; Pohl, C.; Lakics, V.

10.1101/2021.07.12.452036 — cell biology — Posted on 2021-07-12

2555 RNA uridyl transferases TUT4/7 differentially regulate miRNA variants depending on the cancer cell-type

Medhi, R.; Price, J.; Furlan, G.; Gorges, B.; Sapetschnig, A.; Miska, E. A.

10.1101/2021.07.12.451846 — molecular biology — Posted on 2021-07-12

2556 Genome-resolved metagenomic analyses reveal the presence of a bacterial endosymbiont in an avian nasal mite (Rhinonyssidae; Mesostigmata)

Osuna-Mascaro, C.; Dona, J.; Johnson, K. P.; de Rojas Alvarez, M.

10.1101/2021.07.12.452008 — molecular biology — Posted on 2021-07-12

2557 Pparα and fatty acid oxidation coordinate hepatic transcriptional architecture

Cavagnini, K. S.; Wolfgang, M. J.

10.1101/2021.07.12.451949 — molecular biology — Posted on 2021-07-12

2558 Disentangling marine microbial networks across space

Deutschmann, I. M.; Delage, E.; Giner, C. R.; Sebastian, M.; Poulain, J.; Aristegui, J.; Duarte, C. M.; Acinas, S. G.; Massana, R.; Gasol, J. M.; Eveillard, D.; Chaffron, S.; Logares, R.

10.1101/2021.07.12.451729 — microbiology — Posted on 2021-07-12

2559 Experimental evolution of Vibrio cholerae: Identification of genes involved in motility in presence of polymyxin B

Giacomucci, S.; Vincent, A. T.; Duperthuy, M.

10.1101/2021.07.12.451780 — microbiology — Posted on 2021-07-12

2560 Nitrous Oxide Enhances Focused Ultrasound Mediated Delivery of Viral Gene Therapy

Shah, B. R.; Bailey, R. M.; Youssef, I.; Holmes, S. K.; Marckx, A.; Estill-Terpac, S. J.; Diamond, M.; Chopra, R.

10.1101/2021.07.11.451978 — neuroscience — Posted on 2021-07-12

2561 Serial dependence tracks objects and scenes independently

Collins, T.

10.1101/2021.07.12.452024 — neuroscience — Posted on 2021-07-12

2562 Improved Interpretability of Brain-Behavior CCA with Domain-driven Dimension Reduction

Liu, Z.; Whitaker, K. J.; Smith, S. M.; Nichols, T.

10.1101/2021.07.12.451975 — neuroscience — Posted on 2021-07-12

2563 The presence of corticomuscular coherence during unipedal stance

Alkaff, S. D.; Ushiyama, J.

10.1101/2021.07.12.452017 — neuroscience — Posted on 2021-07-12

2564 Molecular Mechanisms for Frequency Specificity in a Drosophila Hearing Organ

Hu, Y.; Jia, Y.; Deng, T.; Liu, T.; Zhang, W.

10.1101/2021.07.11.451973 — neuroscience — Posted on 2021-07-12

2565 A corollary discharge mediates saccade related inhibition of single units in mnemonic structures of the human brain

Katz, C. N.; Schjetnan, A. G. P.; Patel, K. V.; Barkley, V.; Hoffman, K. L.; Kalia, S. K.; Duncan, K.; Valiante, T. A.

10.1101/2021.07.12.450085 — neuroscience — Posted on 2021-07-12

2566 Loss of muscarinic M5 receptor function manifests disparate impairments in exploratory behavior in male and female mice despite common dopamine regulation

Razidlo, J. A.; Fausner, S. M.; Wang, L. C.; Mirza, S. A.; Alvarez, V. A.; Lemos, J. C.

10.1101/2021.07.11.451965 — neuroscience — Posted on 2021-07-12

2567 Sex Identification in Cattle, based on Amelogenin Gene

Ahmad, A.; Israr, M.; Rahat, M. A.; Wahab, A.; Uddin, S.; Rasool, A.; Akbar, F.; Shah, M.

10.1101/2021.07.11.451984 — zoology — Posted on 2021-07-12

2568 Variation in root system architecture among the founder parents of two 8-way MAGIC wheat populations for selection in breeding

Pariyar, S.; Nagel, K. A.; Lentz, J.; Galinski, A.; Wilhelm, J.; Putz, A.; Adels, S.; Heinz, K.; Frohberg, C.; Watt, M.

10.1101/2021.07.12.451891 — plant biology — Posted on 2021-07-12

2569 Conditional ERK3 overexpression cooperates with PTEN deletion to promote lung adenocarcinoma formation in mice

Vallabhaneni, S.; Liu, J.; Morel, M.; Wang, W.; Demayo, F. J.; Long, W.

10.1101/2021.07.11.451860 — cancer biology — Posted on 2021-07-12

2570 Learning cell communication from spatial graphs of cells

Fischer, D. S.; Schaar, A. C.; Theis, F. J.

10.1101/2021.07.11.451750 — bioinformatics — Posted on 2021-07-12

2571 SurvBenchmark: comprehensive benchmarking study of survival analysis methods using both omics data and clinical data

Zhang, Y.; Wong, G.; Mann, G.; Muller, S.; Yang, J. Y. H.

10.1101/2021.07.11.451967 — bioinformatics — Posted on 2021-07-12

2572 Critical Assessment of Metagenome Interpretation - the second round of challenges

Meyer, F.; Fritz, A.; Deng, Z.-L.; Koslicki, D.; Gurevich, A.; Robertson, G.; Zhu, J.; Jia, H.; Kola, A.; Limasset, A.; Kolmogorov, M.; Egan, R.; Rosen, G. L.; Cristian, A.; Zhao, Z.; Gray, M. A.; Nissen, J.; Zeller, G.; Paoli, L.; Ruscheweyh, H.-J.; Milanese, A.; Sunagawa, S.; Alser, M.; Shi, L.; Chen, B.; Wang, Z.; Wang, Z.; Huang, P.; You, R.; Sun, F.; Zhu, S.; Bertrand, D.; Tong, C.; Li, C.; Nagarajan, N.; Renard, B.; Malcher-Miranda, F.; Piro, V. C.; Chikhi, R.; Vicedomini, R.; Wang, Z.; Thomas, A.; Tremblay, J.; Dabrowski, P. W.; Nurk, S.; Jorgensen, T. S.; Willassen, N. P.; Klemetsen, T

10.1101/2021.07.12.451567 — bioinformatics — Posted on 2021-07-12

2573 We are not ready yet: limitations of transfer learning for Disease Named Entity Recognition

Langnickel, L.; Fluck, J.

10.1101/2021.07.11.451939 — bioinformatics — Posted on 2021-07-12

2574 An integrated analysis tool reveals intrinsic biases in gene set enrichment

Thakur, N.; Pujol, N.; van Helden, J.; Waterston, R. H.; Hillier, L. W.; Tichit, L.; Ewbank, J. J.

10.1101/2021.07.12.452009 — bioinformatics — Posted on 2021-07-12

2575 Binomial models uncover biological variation during feature selection of droplet-based single-cell RNA sequencing

Sparta, B.; Hamilton, T.; Aragones, S. D.; Deeds, E. J.

10.1101/2021.07.11.451989 — bioinformatics — Posted on 2021-07-12

2576 Longitudinal in vivo changes in radial peripapillary capillaries and optic nerve head structure in non-human primates with early experimental glaucoma

Musial, G.; Adhikari, S.; Mirhajianmoghadam, H.; Queener, H. M.; Schill, A. W.; Patel, N. B.; Porter, J.

10.1101/2021.07.11.450534 — bioengineering — Posted on 2021-07-12

2577 Chemoproteomic profiling reveals cellular targets of nitro-fatty acids

Fang, M.; Huang, K. H.; Tu, W.-J.; Chen, Y.-T.; Pan, P.-Y.; Hsiao, W.-C.; Ke, Y.-Y.; Tsou, L. K.; Zhang, M. M.

10.1101/2021.07.12.451990 — biochemistry — Posted on 2021-07-12

2578 Mapping the nuclear microenvironment of genes at agenome-wide scale

Yildirim, A.; Hua, N.; Boninsegna, L.; Polles, G.; Gong, K.; Hao, S.; Li, W.; Zhou, X. J.; Alber, F.

10.1101/2021.07.11.451976 — genomics — Posted on 2021-07-12

2579 Native MOWChIP-seq: Genome-wide profiles of key protein bindings reveal functional differences among various brain regions

Liu, Z.; Naler, L. B.; Zhu, Y.; Deng, C.; Zhang, Q.; Zhu, B.; Zhou, Z.; Sarma, M.; Murray, A.; Xie, H.; Lu, C.

10.1101/2021.07.11.451963 — genomics — Posted on 2021-07-12

2580 I alternate therefore I generalize: how the intrinsic resistance risk of fungicides counterbalances their durability

Ballu, A.; Despreaux, P.; Duplaix, C.; Deredec, A.; Carpentier, F.; Walker, A.-S.

10.1101/2021.07.11.451819 — evolutionary biology — Posted on 2021-07-12

2581 ERK-mediated Curvature Feedback Regulates Branching Morphogenesis in Lung Epithelial Tissue

Hirashima, T.; Matsuda, M.

10.1101/2021.07.11.451982 — developmental biology — Posted on 2021-07-12

2582 Lentiviral vector optimization enhances the expression and cytotoxicity of chimeric antigen receptors

Guo, C.; Chen, H.; Yu, J.; Lu, H.; Guo, X.; Li, X.; Wang, T.; Zhi, L.; Niu, Z.; Zhu, W.

10.1101/2021.07.11.451925 — cell biology — Posted on 2021-07-12

2583 Artemisinin acts by inhibiting Plasmodium falciparum Ddi1, a retropepsin, resulting into the accumulation of ubiquitinated proteins

Onchieku, N. M.; Kumari, S.; Pandey, R.; Sharma, V.; Kumar, M.; Deshmukh, A.; Kaur, I.; Mohmmed, A.; Gupta, D.; Kiboi, D.; Gaur, N.; Malhotra, P.

10.1101/2021.07.12.452004 — cell biology — Posted on 2021-07-12

2584 The retrotransposon R2 maintains Drosophila ribosomal DNA repeats

Nelson, J. O.; Slicko, A.; Yamashita, Y. M.

10.1101/2021.07.12.451825 — cell biology — Posted on 2021-07-12

2585 PROTEOMIC SIGNATURES OF MICROBIAL ADAPTATION TO THE HIGHEST UV -IRRADIATION ON EARTH: LESSONS FROM A SOIL ACTINOBACTERIUM

Zannier, F.; Portero, L. R.; Douki, T.; Gärtner, W.; Albarracin, V. H.

10.1101/2021.07.11.451938 — molecular biology — Posted on 2021-07-12

2586 Pathogenic and transcriptomic differences of emerging SARS-CoV-2 variants in the Syrian golden hamster model

O'Donnell, K. L.; Pinski, A. N.; Clancy, C. S.; Gourdine, T.; Shifflett, K.; Fletcher, P.; Messaoudi, I.; Marzi, A.

10.1101/2021.07.11.451964 — microbiology — Posted on 2021-07-12

2587 Double nicking by RNA-directed Cascade-nCas3 for high-efficiency large-scale genome engineering

Hao, Y.; Wang, Q.; Li, J.; Yang, S.; Ma, L.; Zheng, Y.; Peng, W.

10.1101/2021.07.12.451994 — microbiology — Posted on 2021-07-12

2588 Collaborations and deceptions in strategic interactions revealed by hyperscanning fMRI

Shen, S.-S.; Cheng, J.-T.; Hsu, Y.-R.; Chen, D.-Y.; Weng, M.-H.; Kung, C.-C.

10.1101/2021.07.11.451985 — neuroscience — Posted on 2021-07-12

2589 Wall-associated Receptor Kinase and The Expression Profiles in Wheat Responding to Fungal Stress

Zhang, H.; Li, H.; Zhang, X.; Yan, W.; Deng, P.; Zhang, Y.; Peng, S.; Wang, Y.; Wang, C.; Ji, W.

10.1101/2021.07.11.451968 — plant biology — Posted on 2021-07-12

2590 SARS-CoV-2 Spike Protein Mutations and Escape from Antibodies: a Computational Model of Epitope Loss in Variants of Concern

Triveri, A.; Serapian, S. A.; Marchetti, F.; Doria, F.; Pavoni, S.; Cinquini, F.; Moroni, E.; Rasola, A.; Frigerio, F.; Colombo, G.

10.1101/2021.07.12.452002 — biophysics — Posted on 2021-07-12

2591 Evaluating de novo assembly and binning strategies for time-series drinking water metagenomes.

Vosloo, S.; Huo, L.; Anderson, C. L.; Rivera, M. S.; Dai, Z.; Pinto, A. J.

10.1101/2021.07.11.451960 — genomics — Posted on 2021-07-12

2592 High rate of mutational events in SARS-CoV-2 genomes across Brazilian geographical regions, February 2020 to June 2021

Souza, U. J. B. d.; Santos, R. N. d.; Campos, F. S.; Lourenco, K. L.; Fonseca, F. G. d.; Spilki, F. R.; Corona-omica.BR MCTI Network,

10.1101/2021.07.10.451922 — genomics — Posted on 2021-07-12

2593 Evolutionary footprints of a cold relic in a rapidly warming world

Wolf, E.; Gaquerel, E.; Scharmann, M.; Yant, L.; Koch, M. A.

10.1101/2021.07.11.451959 — evolutionary biology — Posted on 2021-07-12

2594 Genetic slippage after sex maintains diversity for parasite resistance in a natural host population

Ameline, C.; Voegtli, F.; Andras, J.; Dexter, E.; Engelstaedter, J.; Ebert, D.

10.1101/2021.07.11.451958 — evolutionary biology — Posted on 2021-07-12

2595 Niclosamide reverses SARS-CoV-2 control of lipophagy

Garrett, T.; Coatsworth, H.; Mahmud, I.; Hamerly, T.; Stephenson, C. J.; Yazd, H.; Ayers, J. B.; Miller, M.; Lednicky, J. A.; Dinglasan, R. R.

10.1101/2021.07.11.451951 — microbiology — Posted on 2021-07-12

2596 Altered costimulatory signals and hypoxia support chromatin landscapes limiting the functional potential of exhausted T cells in cancer

Ford, B. R.; Rittenhouse, N. L.; Scharping, N. E.; Vignali, P. D. A.; Frisch, A. T.; Peralta, R.; Delgoffe, G. M.; Poholek, A. C.

10.1101/2021.07.11.451947 — immunology — Posted on 2021-07-12

2597 Effects of Frontoparietal Theta tACS on Verbal Working Memory: Behavioral and Neurophysiological Analysis

Hu, Z.; Samuel, I. B. H.; Meyyappan, S.; Bo, K.; Rana, C.; Ding, M.

10.1101/2021.07.11.451931 — neuroscience — Posted on 2021-07-12

2598 Chemically Induced Senescence in Human Stem Cell-Derived Neurons Promotes Phenotypic Presentation of Neurodegeneration

Fathi, A.; Mathivanan, S.; Kong, L.; Petersen, A. J.; Harder, C. R. K.; Block, J.; Miller, J. M.; Bhattacharyya, A.; Wang, D.; Zhang, S.-C.

10.1101/2021.07.11.451956 — neuroscience — Posted on 2021-07-12

2599 Spatio-Temporal Recruitment Of Adult Neural Stem Cells For Transient Neurogenesis During Pregnancy

Chaker, Z.; Segalada, C.; Doetsch, F.

10.1101/2021.07.11.451957 — neuroscience — Posted on 2021-07-12

2600 Active components of commonly prescribed medicines affect influenza A virus-host cell interaction: a pilot study

Ianevski, A.; Yao, R.; Zusinaite, E.; Lysvand, H.; Oksenych, V.; Tenson, T.; Bjoras, M.; Kainov, D. E.

10.1101/2021.07.11.451833 — pharmacology and toxicology — Posted on 2021-07-12

2601 Circuit motifs and graph properties of connectome development in C. elegans

Matelsky, J. K.; Norman-Tenazas, R.; Davenport, F.; Reilly, E. P.; Gray-Roncal, W. R.

10.1101/2021.07.11.451911 — bioinformatics — Posted on 2021-07-12

2602 Ecology and transmission of a dengue virus serotype 4 identified in wild Aedes aegypti in Florida

Ayers, J. B.; Xie, X.; Coatsworth, H.; Stephenson, C. J.; Waits, C. M.; Shi, P. Y.; Dinglasan, R. R.

10.1101/2021.07.11.451177 — microbiology — Posted on 2021-07-12

2603 Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua

Kim, S.; Park, G.-Y.; Park, J. S.; Park, J.; Hong, H.; Lee, Y.

10.1101/2021.07.11.451936 — immunology — Posted on 2021-07-12

2604 Dynamics of glioma-associated microglia and macrophages reveals their divergent roles in the immune response of brain

Qian, J.; Wang, C.; Wang, B.; Li, C.; Fu, K.; Wang, Y.; Gao, Y.; Niu, C.; Zhao, C.; Liu, J.; Wang, L.; Liu, R.; Luo, F.; Lu, M.; Liu, Y.; Chu, Y.

10.1101/2021.07.11.451874 — immunology — Posted on 2021-07-12

2605 The Automated Preprocessing Pipe-Line for the Estimation of Scale-wise Entropy from EEG Data (APPLESEED): Development and validation for use in pediatric populations

Puglia, M. H.; Slobin, J. S.; Williams, C. L.

10.1101/2021.07.10.450198 — neuroscience — Posted on 2021-07-12

2606 Membrane activity of a DNA-based ion channel depends on the stability of its double-stranded structure.

Morzy, D.; Joshi, H.; Sandler, S. E.; Aksimentiev, A.; Keyser, U. F.

10.1101/2021.07.11.451603 — synthetic biology — Posted on 2021-07-12

2607 A novel non-antibiotic selectable marker GASA6 for plant transformation

Luo, Y.; Gu, J.; Wang, X.; Zhang, S.

10.1101/2021.07.10.451893 — plant biology — Posted on 2021-07-12

2608 Odorization of Natural Gas: What are the Challenges?

Wise, P.; Rowe, S.; Dalton, P.

10.1101/2021.07.10.450231 — physiology — Posted on 2021-07-12

2609 Evolution of a confluent gut epithelium under cyclic stretching

Geremie, L.; Ilker, E.; Bernheim-Dennery, M.; Cavaniol, C.; Viovy, J.-L.; Matic Vignjevic, D.; Joanny, J.-F.; Descroix, S.

10.1101/2021.07.10.451888 — biophysics — Posted on 2021-07-12

2610 Power Calculator for Detecting Allelic Imbalance Using Hierarchical Bayesian Model

Sherbina, K.; Leon-Novelo, L. G.; Nuzhdin, S. V.; McIntyre, L. M.; Marroni, F.

10.1101/2021.07.10.451873 — bioinformatics — Posted on 2021-07-12

2611 Enhancing Precision in Bioprinting Utilizing Fuzzy Systems

Sedigh, A.; DiPiero, D.; Shine, K. M.; Tomlinson, R.

10.1101/2021.07.10.451921 — bioinformatics — Posted on 2021-07-12

2612 CADD-SV - a framework to score the effects of structural variants in health and disease

Kleinert, P.; Kircher, M.

10.1101/2021.07.10.451798 — bioinformatics — Posted on 2021-07-12

2613 Inferring the demographic history of tetraploid species from genomic data

Roux, C.; Vekemans, X.; Pannell, J.

10.1101/2021.07.10.451876 — genomics — Posted on 2021-07-12

2614 A statistical framework for differential pseudotime analysis with multiple single-cell RNA-seq samples

Hou, W.; Ji, Z.; Chen, Z.; Wherry, E. J.; Hicks, S. C.; Ji, H.

10.1101/2021.07.10.451910 — genomics — Posted on 2021-07-12

2615 Gluconobacter oxydans Knockout Collection Finds Improved Rare Earth Element Extraction

Schmitz, A. M.; Pian, B.; Medin, S.; Reid, M. C.; Wu, M.; Gazel, E.; Barstow, B.

10.1101/2021.07.11.451920 — genomics — Posted on 2021-07-12

2616 Multiple shifts in gene network interactions shape phenotypes of Drosophila melanogaster selected for long and short night sleep duration

Souto-Maior, C.; Lin, Y.; Serrano Negron, Y. L.; Harbison, S. T.

10.1101/2021.07.11.451943 — genomics — Posted on 2021-07-12

2617 High-resolution estimates of crossover and noncrossover recombination from a captive baboon colony

Wall, J.; Robinson, J. A.; Cox, L. A.

10.1101/2021.07.10.451667 — genomics — Posted on 2021-07-12

2618 Independent adoptions of a set of proteins found in the matrix of the mineralized shell-like eggcase of Argonaut octopuses

Setiamarga, D. H. E.; Hirota, K.; Ikai, R.; Imoto, S.; Sato, N.; Ono, H.; Isowa, Y.; Yonemitsu, H.; Sasaki, T.; Yoshida, M.-a.

10.1101/2021.07.10.451900 — evolutionary biology — Posted on 2021-07-12

2619 Antigenic evolution of human influenza H3N2 neuraminidase is constrained by charge balancing

Wang, Y.; Lei, R.; Nourmohammad, A.; Wu, N. C.

10.1101/2021.07.10.451918 — evolutionary biology — Posted on 2021-07-12

2620 Evolution with private resources reverses some changes from long-term evolution with public resources

van Raay, K.; Stolyar, S.; Sevigny, J.; Draghi, J.; Lenski, R. E.; Marx, C. J.; Kerr, B.; Zaman, L.

10.1101/2021.07.11.451942 — evolutionary biology — Posted on 2021-07-12

2621 Suppressed eusocial reproduction supports evolutionary convergence over co-option

Velasque, M.; Yongkai, T.; Liu, A. W.; Luscombe, N. M.; Denton, J. A.

10.1101/2021.07.11.451940 — evolutionary biology — Posted on 2021-07-12

2622 Effects of long-lasting insecticide net (LLINs) ownership/utilisation indicators on annual household malaria episodes (AHMEs) in three Health Districts in Cameroon

Cho, F. N.; Fru, P. N.; Cho, B. M.; Munguh, S. F.; Jokwi, P. K.; Ngah, Y. E.; Fru, C. N.; Tassang, A. N.; Ekobo, A. S.

10.1101/488445 — epidemiology — Posted on 2021-07-09

2623 A recombinant protein containing influenza viral conserved epitopes and superantigen induces broad-spectrum protection

Li, Y.; Xu, M.; Li, Y.; Gu, W.; Halimu, G.; Li, Y.; Zhang, Z.; Zhou, L.; Liao, H.; Yao, S.; Zhang, H.; Zhang, C.

10.1101/2021.07.08.451596 — epidemiology — Posted on 2021-07-10

2624 The functional form of specialized predation dramatically affects whether Janzen-Connell effects can prevent competitive exclusion

Smith, D. J. B.

10.1101/2021.07.10.451901 — ecology — Posted on 2021-07-12

2625 A multiple hypotheses framework to study movement ecology and diet in a migratory songbird

Contina, A.; Pierce, A. K.; Yanco, S. W.; Bridge, E. S.; Kelly, J. F.; Wunder, M. B.

10.1101/2021.07.10.451926 — ecology — Posted on 2021-07-12

2626 Reproductive success is influenced by early development: the covariation of natal body size and reproductive performance in grey seals (Halichoerus grypus)

Badger, J.; Bowen, W. D.; den Heyer, N.; Breed, G. A.

10.1101/2021.07.10.451928 — ecology — Posted on 2021-07-12

2627 Consistent differences among individuals more influential than energetic trade-offs in life history variation in grey seals (Halichoerus grypus)

Badger, J.; Bowen, W. D.; den Heyer, N.; Breed, G. A.

10.1101/2021.07.10.451927 — ecology — Posted on 2021-07-12

2628 A connectome-based neuromarker of the non-verbal number acuity and arithmetic skills

Zhang, D.; Zhou, L.; Yang, A.; Li, S.; Chang, C.; Zhou, K.; Liu, J.

10.1101/2021.07.09.451740 — neuroscience — Posted on 2021-07-12

2629 Interhemispheric functional connectivity in the primary motor cortex distinguishes between training on a physical and a virtual surgical simulator

Dutta, A.; Kamat, A.; Makled, B.; Norfleet, J.; Intes, X.; De, S.

10.1101/2021.07.10.451831 — neuroscience — Posted on 2021-07-12

2630 A dynamic pink noise paradigm to assess spatial-temporal attention without biasing perceptual processing

Hanning, N. M.; Deubel, H.

10.1101/2021.07.10.451930 — neuroscience — Posted on 2021-07-12

2631 Non-invasive imaging of tau-targeted probe uptake by whole brain multi-spectral optoacoustic tomography

Vagenknecht, P.; Ono, M.; Luzgin, A.; Ji, B.; Higuchi, M.; Noain, D.; Maschio, C.; Sobek, J.; Chen, Z.; Konietzko, U.; Gerez, J. A.; Riek, R.; Nitsch, R. M.; Razansky, D.; Klohs, J.; Dean-Ben, X. L.; Ni, R.

10.1101/2021.07.10.451626 — neuroscience — Posted on 2021-07-12

2632 Remodeling of organelles and microtubules during spermiogenesis in the liverwort Marchantia polymorpha

Minamino, N.; Norizuki, T.; Mano, S.; Ebine, K.; Ueda, T.

10.1101/2021.07.10.451882 — plant biology — Posted on 2021-07-12

2633 Amino acid availability is not essential for lifespan extension by dietary restriction in the fly

Gautrey, S. L.; Simons, M. J. P.

10.1101/2021.07.10.451902 — physiology — Posted on 2021-07-12

2634 The co-evolution of the genome and epigenome in colorectal cancer

Heide, T.; Househam, J.; Spiteri, I.; Lynn, C.; Cresswell, G. D.; Mossner, M.; Kimberley, C.; Fernandez-Mateos, J.; Chen, B.; Zapata, L.; James, C.; Barozzi, I.; Chkhaidze, K.; Nichol, D.; Berner, A.; Schmidt, M.; Lakatos, E.; Baker, A.-M.; Costa, H.; Mitchinson, M.; Jansen, M.; Caravagna, G.; Ramazzotti, D.; Shibata, D.; Bridgewater, J.; Rodriguez-Justo, M.; Magnani, L.; Graham, T. A.; Sottoriva, A.

10.1101/2021.07.12.451121 — cancer biology — Posted on 2021-07-12

2635 Identification of RNA base pairs and complete assignment of nucleobase resonances by proton-detected solid-state NMR spectroscopy at 100 kHz MAS

Aguion, P. I.; Kirkpatrick, J.; Carlomagno, T.; Marchanka, A.

10.1101/2021.07.11.450890 — biophysics — Posted on 2021-07-12

2636 Adsorption of Lysozyme Into a Charged Confining Pore

Carvalho, S.; Metzler, R.; Cherstvy, A.; Caetano, D.

10.1101/2021.07.11.451934 — biophysics — Posted on 2021-07-12

2637 Z-DNA as a Touchstone for Additive Empirical Force Fields and a Refinement of the Alpha/Gamma DNA torsions for AMBER

Zgarbova, M.; Sponer, J.; Jurecka, P.

10.1101/2021.07.11.451955 — biophysics — Posted on 2021-07-12

2638 Novel Roles of G-quadruplexes on Enhancers in human chromatin

Hou, Y.; Guo, Y.; Dong, S.-S.; Yang, T.-L.

10.1101/2021.07.12.451993 — bioinformatics — Posted on 2021-07-12

2639 Assessing Reproducibility of High-throughput Experiments in the Case of Missing Data.

Singh, R.; Zhang, F.; Li, Q.

10.1101/2021.07.10.451851 — bioinformatics — Posted on 2021-07-12

2640 Attention-based convolutional neural networks for protein-protein interaction site prediction

Lu, S.; Li, Y.; Nan, X.; Zhang, S.

10.1101/2021.07.10.451856 — bioinformatics — Posted on 2021-07-12

2641 Serotonin GPCR-based biosensing modalities in yeast

Lengger, B.; Hoch-Schneider, E. E.; Noerskov, C.; Jakociunas, T.; Jensen, E. D.; Jensen, M. K.

10.1101/2021.07.12.452006 — bioengineering — Posted on 2021-07-12

2642 Molecular architecture of the human tRNA ligase complex

Kroupova, A.; Ackle, F.; Boneberg, F. M.; Chui, A.; Weitzer, S.; Faini, M.; Leitner, A.; Aebersold, R.; Martinez, J.; Jinek, M.

10.1101/2021.07.11.451954 — biochemistry — Posted on 2021-07-12

2643 The habenula clock influences prediction of danger

Basnakova, A.; Cheng, R.-K.; Chia, J. S. M.; D'Agostino, G. A.; Suryadi, ; Tan, G. J. H.; Langley, S. R.; Jesuthasan, S. J.

10.1101/2020.04.29.067108 — neuroscience — Posted on 2021-07-12

2644 Brain-engrafted macrophages provide protection against therapeutic irradiation and secondary concussive injury

Feng, X.; Frias, E.; Paladini, M.-S.; Chen, D.; Boosalis, Z.; Becker, M.; Gupta, S.; Liu, S.; Gupta, N.; Rosi, S.

10.1101/794354 — neuroscience — Posted on 2021-07-12

2645 Illumina iSeq 100 and MiSeq exhibit similar performance in freshwater fish environmental DNA metabarcoding

Nakao, R.; Inui, R.; Akamatsu, Y.; Goto, M.; Matsuoka, S.; Doi, H.

10.1101/2020.08.04.228080 — ecology — Posted on 2021-07-12

2646 Enhancing the darkside: Asymmetric gain of cone photoreceptors underpins discrimination of visual scenes based on their skewness

Yedutenko, M.; Howlett, M. H. C.; Kamermans, M.

10.1101/2021.04.29.441966 — neuroscience — Posted on 2021-07-12

2647 Uncovering the mechanisms of real-world attentional control over the course of primary education

Turoman, N.; Tivadar, R. I.; Retsa, C.; Maillard, A. M.; Scerif, G.; Matusz, P. J.

10.1101/2020.10.20.342758 — neuroscience — Posted on 2021-07-12

2648 Early reduction in PD-L1 expression predicts faster treatment response in human cutaneous leishmaniasis

Dey, N. S.; Senarathna, S.; Somaratne, V.; Madarasinghe, N.; Seneviratne, B.; Forrester, S. S.; Montes De Oca, M.; Reis, L. C.; Moulik, S.; Walrad, P.; Chatterjee, M.; Goto, H.; Wickremasinghe, R.; Lagos, D.; Kaye, P. M.; Ranasinghe, S.

10.1101/2020.02.21.959528 — immunology — Posted on 2021-07-12

2649 Motor dysfunction in Drosophila melanogaster as a biomarker for developmental neurotoxicity

Cabrita, A.; Medeiros, A. M.; Pereira, T.; Rodrigues, A. S.; Kranendonk, M.; Mendes, C. S.

10.1101/2021.07.09.451676 — neuroscience — Posted on 2021-07-12

2650 Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia

Gong, R.; Jiang, F.; Moreland, Z. G.; Reynolds, M. J.; Espinosa de los Reyes, S.; Gurel, P. S.; Shams, A.; Bowl, M. R.; Bird, J. E.; Alushin, G. M.

10.1101/2021.07.09.451843 — biophysics — Posted on 2021-07-12

2651 The changes in the p53 protein across the animal kingdom pointing to its involvement in longevity

Bartas, M.; Brazda, V.; Volna, A.; Cerven, J.; Pecinka, P.; Zawacka-Pankau, J.

10.1101/2020.05.06.080200 — bioinformatics — Posted on 2021-07-12

2652 An initial 'snapshot' of sensory information biases the likelihood and speed of subsequent changes of mind

Turner, W.; Feuerriegel, D.; Hester, R.; Bode, S.

10.1101/2020.11.26.400630 — animal behavior and cognition — Posted on 2021-07-12

2653 A New Likelihood-based Test for Natural Selection

Simon, H. E.; Huttley, G. A.

10.1101/2021.07.04.451068 — genetics — Posted on 2021-07-12

2654 High-throughput variant detection using a color-mixing strategy

Xie, N. G.; Zhang, K.; Song, P.; Li, R.; Luo, J.; Zhang, D. Y.

10.1101/2021.06.30.450651 — genetics — Posted on 2021-07-12

2655 Evaluation of seasonal dynamics of fungal DNA assemblages in a flow-regulated stream in a restored forest using eDNA metabarcoding

Matsuoka, S.; Sugiyama, Y.; Shimono, Y.; Ushio, M.; Doi, H.

10.1101/2020.12.10.420661 — ecology — Posted on 2021-07-12

2656 The effects of multi-day rTMS and cardiorespiratory fitness on working memory and local GABA concentration

Hendrikse, J. J.; Thompson, S.; Suo, C.; Yucel, M.; Rogasch, N. C.; Coxon, J.

10.1101/2020.09.09.288910 — neuroscience — Posted on 2021-07-12

2657 Enhancing the darkside: Asymmetric gain of cone photoreceptors underpins discrimination of visual scenes based on their skewness

Yedutenko, M.; Howlett, M. H. C.; Kamermans, M.

10.1101/2021.04.29.441966 — neuroscience — Posted on 2021-07-12

2658 Neural Activation in the Olfactory Epithelium of East African Cichlid in Response to Odorant Exposure

Kawamura, R.; Nikaido, M.

10.1101/2021.05.25.445711 — neuroscience — Posted on 2021-07-12

2659 Differential Conditioning Produces Merged Long-term Memory in Drosophila

Zhao, B.; Sun, J.; Li, Q.; Zhong, Y.

10.1101/2021.01.13.426486 — neuroscience — Posted on 2021-07-12

2660 Cellular and molecular mechanisms involved in LTP induced by mild theta-burst stimulation in hippocampal slices from young male rats: from weaning to adulthood.

Rodrigues, N. C.; Silva-Cruz, A.; Caulino-Rocha, A.; Bento-Oliveira, A.; Ribeiro, J. A.; Cunha-Reis, D.

10.1101/2021.04.19.440440 — neuroscience — Posted on 2021-07-12

2661 Towards rainy Arctic winters: experimental icing impacts tundra plant productivity and reproduction

Le Moullec, M.; Hendel, A.-L.; Petit Bon, M.; Jonsdottir, I. S.; Varpe, O.; van der Wal, R.; Beumer, L.; Layton-Matthews, K.; Isaksen, K.; Hansen, B. B.

10.1101/2021.06.10.447955 — plant biology — Posted on 2021-07-12

2662 Effect of Cholesterol vs. Ergosterol on DPPC Bilayer Properties: Insights from Atomistic Simulations

Alavizargar, A.; Keller, F.; Wedlich-Soldner, R.; Heuer, A.

10.1101/2020.07.23.216341 — biophysics — Posted on 2021-07-12

2663 The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth

10.1101/520536 — developmental biology — Posted on 2021-07-12

2664 Bacteria are everywhere, even in your COI marker gene data!

Zafeiropoulos, H.; Gargan, L.; Hintikka, S.; Pavloudi, C.; Carlsson, J.

10.1101/2021.07.10.451903 — bioinformatics — Posted on 2021-07-11

2665 Distributed and multifaceted effects of threat and safety

Morrow, K.; Murty, D. V. P. S.; Kim, J.; Song, S.; Hu, K.; Pessoa, L.

10.1101/2021.07.11.451944 — neuroscience — Posted on 2021-07-11

2666 Coupled protein synthesis and ribosome-guided piRNA processing on mRNAs

Sun, Y. H.; Wang, R. H.; Du, K.; Zheng, J.; Xie, L. H.; Pereira, A. A.; Zhang, C.; Ricci, E. P.; Li, X. Z.

10.1101/2021.07.10.451906 — molecular biology — Posted on 2021-07-11

2667 Directional Gaussian Mixture Models of the gut microbiome elucidate microbial spatial structure

Pasarkar, A. P.; Joseph, T. A.; Pe'er, I.

10.1101/2021.07.09.451866 — bioinformatics — Posted on 2021-07-11

2668 Scalable full-transcript coverage single cell RNA sequencing with Smart-seq3xpress

Hagemann-Jensen, M.; Ziegenhain, C.; Sandberg, R.

10.1101/2021.07.10.451889 — genomics — Posted on 2021-07-11

2669 Molecular spikes: a gold standard for single-cell RNA counting

Ziegenhain, C.; Hendriks, G.-J.; Hagemann-Jensen, M.; Sandberg, R.

10.1101/2021.07.10.451877 — genomics — Posted on 2021-07-11

2670 Genetic similarity enhances the strength of the relationship between gut bacteria and host DNA methylation

Zhou, J.; Tesfamicael, K.; Zhou, S. J.; Rollins, L. A.; Rodriguez Lopez, C. M.

10.1101/2021.07.10.451923 — molecular biology — Posted on 2021-07-11

2671 CARPOOL: A library-based platform to rapidly identify next generation chimeric antigen receptors

Kyung, T.; Gordon, K. S.; Perez, C. R.; Holec, P. V.; Ramos, A.; Zhang, A. Q.; Liu, Y.; Koch, C.; Starchenko, A.; Joughin, B.; Lauffenburger, D. A.; Irvine, D. J.; Hemann, M. T.; Birnbaum, M. E.

10.1101/2021.07.09.450900 — immunology — Posted on 2021-07-11

2672 Longitudinal changes in brain activation underlying reading fluency

Ozernov-Palchik, O.; Sury, D.; Turesky, T. K.; Yu, X.; Gaab, N.

10.1101/2021.07.09.451857 — neuroscience — Posted on 2021-07-11

2673 DYT-TOR1A Subcellular Proteomics Reveals Selective Vulnerability of the Nuclear Proteome to Cell Stress

Shroff, K.; Caffall, Z. F.; Calakos, N.

10.1101/2021.07.10.451533 — neuroscience — Posted on 2021-07-11

2674 Adolescent Brain Cognitive Development (ABCD) Community MRI Collection and Utilities

Feczko, E.; Conan, G.; Marek, S.; Tervo-Clemens, B.; Cordova, M.; Doyle, O.; Earl, E.; Perrone, A.; Sturgeon, D.; Klein, R.; Harman, G.; Kilamovich, D.; Hermosillo, R.; Miranda-Dominguez, O.; Adebimpe, A.; Bertolero, M.; Cieslak, M.; Covitz, S.; Hendrickson, T.; Juliano, A. C.; Snider, K.; Moore, L. A.; Uriartel, J.; Graham, A. M.; Calabro, F.; Rosenberg, M. D.; Rapuano, K. M.; Casey, B.; Watts, R.; Hagler, D.; Thompson, W. K.; Nichols, T. E.; Hoffman, E.; Luna, B.; Garavan, H.; Satterthwaite, T. D.; Feldstein Ewing, S.; Nagel, B.; Dosenbach, N. U.; Fair, D. A.

10.1101/2021.07.09.451638 — neuroscience — Posted on 2021-07-11

2675 Viscoelastic Parameterization of Human Skin Cells to Characterize Material Behavior at Multiple Timescales

Parvini, C. H.-R.; Cartagena-Rivera, A. X.; Solares, S. D.

10.1101/2021.07.09.451793 — biophysics — Posted on 2021-07-11

2676 Allosteric effect of nanobody binding on ligand-specific active states of the β2-Adrenergic Receptor

Chen, Y.; Fleetwood, O.; Perez-Conesa, S.; Delemotte, L.

10.1101/2021.07.10.451885 — biophysics — Posted on 2021-07-11

2677 Benchmarking long-read genome sequence alignment tools for human genomics applications

LoTempio, J. E.; Delot, E.; Vilain, E.

10.1101/2021.07.09.451840 — bioinformatics — Posted on 2021-07-11

2678 Structure of ATP synthase from ESKAPE pathogen Acinetobacter baumannii

Demmer, J. K.; Phillips, B. P.; Uhrig, O. L.; Filloux, A.; Allsopp, L. P.; Bublitz, M.; Meier, T.

10.1101/2021.07.10.451757 — biochemistry — Posted on 2021-07-11

2679 Allometry, sexual selection, and evolutionary lines of least resistance shaped the evolution of exaggerated sexual traits within the genus Tyrannus

Fasanelli, M. N.; Milla Carmona, P. S.; Soto, I. M.; Tuero, D. T.

10.1101/2021.07.09.451836 — evolutionary biology — Posted on 2021-07-11

2680 REPINs are facultative genomic symbionts of bacterial genomes

Bertels, F.; Rainey, P. B.

10.1101/2021.07.10.451892 — evolutionary biology — Posted on 2021-07-11

2681 Dataset on the mass spectrometry-based proteomic profiling of mouse embryonic fibroblasts from a wild type and DYT-TOR1A mouse model of dystonia, basally and during stress

Shroff, K.; Caffall, Z. F.; Soderblom, E. J.; Waitt, G.; Ho, T.; Calakos, N.

10.1101/2021.07.09.451632 — cell biology — Posted on 2021-07-11

2682 Bacterial type 1A topoisomerases maintain the stability of the genome by preventing and dealing with R-loop-and nucleotide excision repair-dependent topological stress.

Brochu, J.; Vlachos-Breton, E.; Drolet, M.

10.1101/2021.07.10.451908 — molecular biology — Posted on 2021-07-11

2683 Glby, is a PBP with β-lactamase activity and is required for in vivo viability of M. abscessus

Lamichhane, G.; Galanis, C.; Maggioncalda, E. C.; Kumar, G.

10.1101/2021.07.11.451952 — microbiology — Posted on 2021-07-11

2684 Pili Expression in Geobacter sulfurreducens Lacking the Putative Gene for the PilB Pilus Assembly Motor

Ueki, T.; Walker, D. J.; Nevin, K. P.; Ward, J. E.; Woodard, T. L.; Nonnenmann, S. S.; Lovley, D. R.

10.1101/2021.07.10.451916 — microbiology — Posted on 2021-07-11

2685 Neurons in the Nucleus Tractus Solitarius are Selective to the Orientation of Gastric Electrical Stimulation

Cao, J.; Wang, X.; Powley, T. L.; Liu, Z.

10.1101/2021.07.09.451818 — neuroscience — Posted on 2021-07-11

2686 The organization of the gravity-sensing system in zebrafish

Liu, Z.; Hildebrand, D. G. C.; Morgan, J. L.; Slimmon, N.; Bagnall, M. W.

10.1101/2021.07.09.451839 — neuroscience — Posted on 2021-07-11

2687 Tracking neural markers of template formation and implementation in attentional inhibition under different distractor consistency

Wen, W.; Huang, Z.; Hou, Y.; Li, S.

10.1101/2021.07.09.451861 — neuroscience — Posted on 2021-07-11

2688 Enhanced chemotaxis through spatially-regulated absolute concentration robustness

Biswas, D.; Bhattacharya, S.; Iglesias, P. A.

10.1101/2021.07.10.451673 — synthetic biology — Posted on 2021-07-11

2689 A patient-driven clinicogenomic partnership through the Metastatic Prostate Cancer Project

10.1101/2021.07.09.451849 — cancer biology — Posted on 2021-07-11

2690 The SARS-CoV-2 spike reversibly samples an open-trimer conformation exposing novel epitopes

Costello, S. M.; Shoemaker, S. R.; Hobbs, H. T.; Nguyen, A. W.; Hsieh, C.-L.; Maynard, J. A.; McLellan, J. S.; Pak, J. E.; Marqusee, S.

10.1101/2021.07.11.451855 — biophysics — Posted on 2021-07-11

2691 Structural basis for carbapenam C-alkylation by TokK, a B12-dependent radical SAM enzyme

Knox, H.; Sinner, E.; Townsend, C.; Boal, A.; Booker, S.

10.1101/2021.07.10.451909 — biochemistry — Posted on 2021-07-11

2692 Targeting the nervous system of the parasitic worm, Haemonchus contortus, with quercetin.

Goel, V.; Chakroborty, N. K.; Sharma, S.; Singla, L. D.; Choudhury, D.

10.1101/2021.07.11.451932 — biochemistry — Posted on 2021-07-11

2693 Unconventional tonicity-regulated nuclear trafficking of NFAT5 mediated by KPNB1, XPOT and RUVBL2

Cheung, C. Y.; Huang, T.-T.; Chow, N.; Zhang, S.; Zhao, Y.; Wong, C. C.; Boassa, D.; Phan, S.; Ellisman, M. H.; Yates, J. R.; Xu, S.; Yu, Z.; Zhang, Y.; Zhang, R.; Ng, L. L.; Ko, B. C. B.

10.1101/2021.07.11.451941 — cell biology — Posted on 2021-07-11

2694 A Massively Parallel Trafficking Assay Accurately Predicts Loss of Channel Function in KCNH2 Variants

Ng, C. A.; Ullah, R.; Farr, J.; Hill, A. P.; Kozek, K. A.; Vanags, L. R.; Mitchell, D. W.; Kroncke, B. M.; Vandenberg, J. I.

10.1101/2021.07.10.451881 — biophysics — Posted on 2021-07-11

2695 Hnf1b-CreER causes efficient recombination of a Rosa26-RFP reporter in duct and islet δ cells

Rovira, M.; Maestro, M. A.; Grau, V.; Ferrer, J.

10.1101/2021.05.23.445318 — developmental biology — Posted on 2021-07-11

2696 Minimal synthetic enhancers reveal control of the probability of transcriptional engagement and its timing by a morphogen gradient

Reimer, A.; Alamos, S.; Westrum, C.; Turner, M. A.; Talledo, P.; Zhao, J.; Garcia, H. G.

10.1101/2021.07.10.451524 — developmental biology — Posted on 2021-07-11

2697 De novo spatiotemporal modelling of cell-type signatures identifies novel cell populations in the developmental human heart

Marco Salas, S.; Yuan, X.; Sylven, C.; Nilsson, M.; Wahlby, C.; Partel, G.

10.1101/2021.07.10.451822 — developmental biology — Posted on 2021-07-11

2698 Functional analysis of Mmd2 and related PAQR genes during sex determination in mice

Zhao, L.; Thomson, E.; Ng, E. T.; Longmuss, E.; Svingen, T.; Bagheri-Fam, S.; Quinn, A.; Harley, V. R.; Harrison, L. C.; Pelosi, E.; Koopman, P.

10.1101/2021.07.10.451886 — developmental biology — Posted on 2021-07-11

2699 Splicing Factor SRSF1 Deficiency in the Liver Triggers NASH-like Pathology via R-Loop Induced DNA Damage and Cell Death

Arif, W.; Mathur, B.; Saikali, M. F.; Chembazhi, U. V.; Blue, S. M.; Yee, B. A.; Van Nostrand, E. L.; Bangru, S.; Hao, Q.; Yeo, G. W.; Prasanth, K. V.; Anakk, S.; Cummins, C. L.; Kalsotra, A.

10.1101/2021.07.10.451875 — cell biology — Posted on 2021-07-11

2700 Condensate-mediated reactivation of mumps virus infection under stress

Zhang, X.; Sridharan, S.; Zagoriy, I.; Eugster Oegema, C.; Ching, C.; Pflaesterer, T.; Fung, H. K. H.; Poser, I.; Mueller, C. W.; Hyman, A. A.; Savitski, M. M.; Mahamid, J.

10.1101/2021.07.10.451879 — cell biology — Posted on 2021-07-11

2701 TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells

Osnato, A.; Brown, S.; Krueger, C.; Andrews, S.; Collier, A. J.; Nakanoh, S.; Quiroga Londono, M.; Wesley, B. T.; Muraro, D.; Brumm, S.; Niakan, K.; Vallier, L.; Ortmann, D.; Rugg-Gunn, P. J.

10.1101/2021.07.10.451887 — cell biology — Posted on 2021-07-11

2702 Tributyltin exposure leads to increased adiposity and reduced abundance of leptogenic bacteria in the zebrafish intestine

Gomez de la Torre Canny, S.; Mueller, O.; Craciunescu, C. V.; Blumberg, B.; Rawls, J. F.

10.1101/2021.07.09.451869 — microbiology — Posted on 2021-07-11

2703 The hidden cost of receiving favors: A theory of indebtedness

Gao, X.; Jolly, E.; Yu, H.; Liu, H.; Zhou, X.; Chang, L. J.

10.1101/2020.02.03.926295 — neuroscience — Posted on 2021-07-11

2704 A Phosphorus-Limitation Induced, Functionally Conserved DUF506 Protein is a Repressor of Root Hair Elongation in Arabidopsis thaliana

Ying, S.; Blancaflor, E.; Liao, F.; Scheible, W. R.

10.1101/2021.07.09.451837 — plant biology — Posted on 2021-07-11

2705 Optimization of the TeraTox assay for preclinical teratogenicity assessment

Jaklin, M.; Zhang, J. D.; Schaefer, N.; Clemann, N.; Barrow, P.; Kueng, E.; Sach-Peltason, L.; McGinnis, C.; Leist, M.; Kustermann, S.

10.1101/2021.07.06.451364 — pharmacology and toxicology — Posted on 2021-07-11

2706 scSGL: Signed Graph Learning for Single-Cell Gene Regulatory Network Inference

Karaaslanli, A.; Saha, S.; Aviyente, S.; Maiti, T.

10.1101/2021.07.08.451697 — bioinformatics — Posted on 2021-07-11

2707 Zygotic contractility awakening during mouse preimplantation development

Özgüc, O.; de Plater, L.; Kapoor, V.; Tortorelli, A.-F.; Maitre, J.-L.

10.1101/2021.07.09.451745 — developmental biology — Posted on 2021-07-11

2708 A novel imaging ligand as a biomarker for mutant huntingtin-lowering in Huntington's disease

Bertoglio, D.; Bard, J.; Hessmann, M.; Liu, L.; Gaertner, A.; De Lombaerde, S.; Huscher, B.; Zajicek, F.; Miranda, A.; Peters, F.; Herrmann, F.; Schaertl, S.; Vasilkovska, T.; Brown, C. J.; Johnson, P. D.; Prime, M. E.; Mills, M. R.; Van der Linden, A.; Mrzljak, L.; Khetarpal, V.; Wang, Y.; Marchionini, D. M.; Skinbjerg, M.; Verhaeghe, J.; Dominguez, C.; Staelens, S.; Munoz-Sanjuan, I.

10.1101/2021.07.09.451725 — neuroscience — Posted on 2021-07-11

2709 Sphingolipids are involved in Pieris brassicae egg-induced cell death in Arabidopsis thaliana

Groux, R.; Fouillen, L.; Mongrand, S.; Reymond, P.

10.1101/2021.07.09.451813 — plant biology — Posted on 2021-07-11

2710 Effects of blue monochromatic light directed at one eye of pregnant horse mares on gestation, parturition and foal maturity

Lutzer, A.; Nagel, C.; Murphy, B. A.; Aurich, J.; Gautier, C.; Aurich, C.

10.1101/2021.07.09.451773 — physiology — Posted on 2021-07-11

2711 One billion synthetic 3D-antibody-antigen complexes enable unconstrained machine-learning formalized investigation of antibody specificity prediction

Robert, P. A.; Akbar, R.; Frank, R.; Pavlovic, M.; Widrich, M.; Snapkov, I.; Chernigovskaya, M.; Scheffer, L.; Slabodkin, A.; Mehta, B. B.; Vu, M. H.; Prosz, A.; Abram, K.; Olar, A.; Miho, E.; Haug, D. T. T.; Lund-Johansen, F.; Hochreiter, S.; Hobaek Haff, I.; Klambauer, G.; Sandve, G. K.; Greiff, V.

10.1101/2021.07.06.451258 — immunology — Posted on 2021-07-11

2712 GWAS-associated variants, non-genetic factors, and transient transcriptome in Multiple Sclerosis etiopathogenesis: a colocalization analysis

Umeton, R.; Bellucci, G.; Bigi, R.; Romano, S.; Buscarinu, M. C.; Renie', R.; Rinaldi, V.; Pizzolato Umeton, R.; Morena, E.; Romano, C.; Mechelli, R.; Salvetti, M.; Ristori, G.

10.1101/2021.03.12.434773 — neuroscience — Posted on 2021-07-10

2713 Antifeedant activities of L-arabinose to caterpillars of the cotton bollworm Helicoverpa armigera (Hübner)

Sun, L.; Hong, Z.-Z.; Ma, Y.; Hou, W.; Liu, L.; Zhao, X.; Yan, F.; Yin, X.; Wang, C.-Z.; Tang, Q.

10.1101/2020.07.20.213033 — animal behavior and cognition — Posted on 2021-07-10

2714 Population dynamics and ranging behaviors of provisioned silvered langur (Trachypithecus cristatus) in Peninsular Malaysia

Mohd-Daut, N.; Matsuda, I.; Abidin, K. Z.; Md-Zain, B. M.

10.1101/2020.12.16.423156 — ecology — Posted on 2021-07-10

2715 Distinct developmental mechanisms influence sexual dimorphisms in the milkweed bug Oncopeltus fasciatus

Just, J.; Laslo, M.; Lee, Y. J.; Yarnell, M. C.; Zhang, Z.; Angelini, D. R.

10.1101/2021.05.12.443917 — developmental biology — Posted on 2021-07-10

2716 BioCCP.jl: Collecting Coupons in combinatorial biotechnology

Van Huffel, K.; Stock, M.; De Baets, B.

10.1101/2021.07.09.451763 — bioengineering — Posted on 2021-07-10

2717 Successful microbial colonization of space using an anti-aggregation strategy

Liu, X.; Wang, M.; Nie, Y.; Wu, X.-L.

10.1101/2021.07.09.451734 — ecology — Posted on 2021-07-10

2718 Biomechanical effects of the addition of a precision constraint on a collective load carriage task

Sghaier, N.; Fumery, G.; Fourcassie, V.; Turpin, N. A.; Moretto, P.

10.1101/2021.07.09.451742 — bioengineering — Posted on 2021-07-10

2719 Tn5 transposase-based epigenomic profiling methods are prone to open chromatin bias

Wang, M.; Zhang, Y.

10.1101/2021.07.09.451758 — genomics — Posted on 2021-07-10

2720 Single-cell bisulfite sequencing of spermatozoa from lean and obese humans reveals potential for the transmission of epimutations

Barres, R.; Andersen, E.; Reik, W.; Clark, S.; Ingerslev, L.; Lundell, L.

10.1101/2021.07.09.451752 — genomics — Posted on 2021-07-10

2721 Selective whole genome amplification as a tool to enrich specimens with low Treponema pallidum genomic DNA copies for whole genome sequencing

Thurlow, C. M.; Joseph, S. J.; Ganova-Raeva, L. M.; Katz, S.; Pereira, L.; Chen, C.-Y.; Debra, A.; Vilfort, K.; Workowski, K.; Cohen, S.; Reno, H.; Sun, Y.; Burroughs, M.; Sheth, M.; Chi, K.-H.; Danavall, D.; Philip, S.; Cao, W.; Kersh, E.; Pillay, A.

10.1101/2021.07.09.451864 — genomics — Posted on 2021-07-10

2722 Mutations in Drosophila tRNA processing factors cause phenotypes similar to Pontocerebellar Hypoplasia

Schmidt, C. A.; Min, L. Y.; McVay, M. H.; Giusto, J. D.; Brown, J. C.; Salzler, H. R.; Matera, A. G.

10.1101/2021.07.09.451847 — genetics — Posted on 2021-07-10

2723 Predictors of the long-term conservation value of sites in a mechanistic metacommunity model

Dinner O'Sullivan, J. L.; Terry, C.; Wilson, R.; Rossberg, A.

10.1101/2021.07.09.451808 — ecology — Posted on 2021-07-10

2724 A whole transcriptomic approach reveals novel mechanisms of organophosphate and pyrethroid resistance in Anopheles arabiensis from Ethiopia

Messenger, L. A.; Impoinvil, L. M.; Derilus, D.; Yewhalaw, D.; Irish, S.; Lenhart, A.

10.1101/2021.07.09.451871 — molecular biology — Posted on 2021-07-10

2725 Borgs are giant extrachromosomal elements with the potential to augment methane oxidation

Al-Shayeb, B.; Schoelmerich, M. C.; West-Roberts, J.; Valentin-Alvarado, L. E.; Sachdeva, R.; Mullen, S.; Crits-Christoph, A.; Wilkins, M. J.; Williams, K. H.; Doudna, J. A.; Banfield, J. F.

10.1101/2021.07.10.451761 — microbiology — Posted on 2021-07-10

2726 A mouse-adapted SARS-CoV-2 strain replicating in standard laboratory mice.

Montagutelli, X.; Prot, M.; Jouvion, G.; Levillayer, L.; Conquet, L.; Reyes-Gomez, E.; Donati, F.; Albert, M.; van der Werf, S.; Jaubert, J.; Simon-Loriere, E.

10.1101/2021.07.10.451880 — microbiology — Posted on 2021-07-10

2727 NSUN2-mediated m5C methylation of IRF3 mRNA negatively regulates type I interferon responses

Wang, H.; Zhang, L.; Zeng, C.; Feng, J.; Zhou, Y.; Xu, K.; Lan, K.; Chen, Y.

10.1101/2021.07.09.451748 — immunology — Posted on 2021-07-10

2728 Nucleolar stress controls mutant Huntingtin toxicity and monitors Huntington disease progression

Soenmez, A.; Mustafa, R.; Ryll, S. T.; Tuorto, F.; Wacheul, L.; Ponti, D.; Litke, C.; Hering, T.; Kojer, K.; Koch, J.; Pitzer, C.; Kirsch, J.; Neueder, A.; Kreiner, G.; Lafontaine, D. L.; Orth, M.; Liss, B.; Parlato, R.

10.1101/2021.07.09.451766 — neuroscience — Posted on 2021-07-10

2729 Neural excitation/inhibition imbalance and the treatment of severe depression

ten Doesschate, F.; Bruin, W.; Zeidman, P.; Abbott, C.; Argyelan, M.; Dols, A.; Emsell, L.; van Eijndhoven, P. F. P.; van Exel, E.; Mulders, P. C. R.; Narr, K. L.; Tendolkar, I.; Rhebergen, D.; Sienaert, P.; Vandenbulcke, M.; Verdijk, J.; van Verseveld, M.; Bartsch, H.; Oltedal, L.; van Waarde, J. A.; van Wingen, G. A.

10.1101/2021.07.09.451784 — neuroscience — Posted on 2021-07-10

2730 One-week escitalopram intake shifts excitation-inhibition balance in the healthy female brain

Zsido, R. G.; Molloy, E. N.; Cesnaite, E.; Zheleva, G.; Beinhölzl, N.; Scharrer, U.; Piecha, F. A.; Regenthal, R.; Villringer, A.; Nikulin, V. V.; Sacher, J.

10.1101/2021.07.09.451806 — neuroscience — Posted on 2021-07-10

2731 Small RNA profiling in Mycobacterium insights into stress adapt ability

Chen, Y.; Zhai, W.; Zhang, K.; Zhu, T.; Su, L.; Bermudez, L. E.; Chen, H.; Guo, A.

10.1101/2021.07.09.451870 — zoology — Posted on 2021-07-10

2732 Development of a fluorescent quantitative real-time polymerase chain reaction assay for the detection of novel-goose parvovirus in vivo

Ma, H.; Li, Y.; Yang, J.

10.1101/2021.07.09.451858 — zoology — Posted on 2021-07-10

2733 Importance of cell division angle, position of cell proliferative area, and localization of AN3 in lateral organ morphology

Kinoshita, A.; Naito, M.; Tsukaya, H.

10.1101/2021.07.09.451862 — plant biology — Posted on 2021-07-10

2734 Photoprotective qH in Arabidopsis occurs in the light-harvesting complex II trimer

Bru, P.; Steen, C. J.; Park, S.; Amstutz, C. L.; Sylak-Glassman, E. J.; Leuenberger, M.; Lam, L.; Longoni, F.; Fleming, G. R.; Niyogi, K. K.; Malnoë, A.

10.1101/2021.07.09.450705 — plant biology — Posted on 2021-07-10

2735 Assessing the Effectiveness of Mycorrhizal Inoculation on the Biochemical Composition of the Different Species of Echinacea

Sharma, A.; Saini, I.; Shankar, B. A.

10.1101/2021.07.09.451863 — plant biology — Posted on 2021-07-10

2736 HepT1-derived murine models of high-risk hepatoblastoma display vascular invasion, metastasis, and circulating tumor cells

Woodfield, S. E.; Mistretta, B. J.; Patel, R. H.; Ibarra, A. M.; Fisher, K. E.; Sarabia, S. F.; Gandhi, I.; Reuther, J.; Starosolski, Z.; Badachhape, A.; Shah, A. P.; Larson, S. R.; Srivastava, R. K.; Shi, Y.; Whitlock, R. S.; Holloway, K.; Roy, A.; Ghaghada, K. B.; Lopez-Terrada, D.; Gunaratne, P. H.; Vasudevan, S. A.

10.1101/2021.07.09.451809 — cancer biology — Posted on 2021-07-10

2737 Novel method for clarifying faster interstitial flow in the intimal side of the aorta under intraluminal pressurization

Fukui, W.; Ujihara, Y.; Nakamura, M.; Sugita, S.

10.1101/2021.07.09.451753 — biophysics — Posted on 2021-07-10

2738 Single-cell transcriptomics for the 99.9% of species without reference genomes

Botvinnik, O. B.; Vemuri, P.; Pierce Ward, N. T.; Logan, P. A.; Nafees, S.; Karanam, L.; Travaglini, K. J.; Ezran, C. S.; Ren, L.; Wang, J.; Huang, Y.; Wang, J.; Brown, C. T.

10.1101/2021.07.09.450799 — bioinformatics — Posted on 2021-07-10

2739 Homology Modelling, In Silico Prediction And Characterization Of Cytochrome c oxidase In Cyprinus carpio And Tubifex tubifex And Molecular Docking Studies Between The Modelled Protein And Three Commonly Used Surfactants Sodium Dodecyl Sulphate, Cetylpyridinium Chloride And Sodium Laureth Sulphate

Bhattacharya, R.; Daoud, I.; Chatterjee, A.; Chatterjee, S.; Saha, N. C.

10.1101/2021.07.09.451643 — bioinformatics — Posted on 2021-07-10

2740 Screening of anti-Acinetobacter baumannii phytochemicals, based on the potential inhibitory effect on OmpA and OmpW functions

Shahryari, S.; Mohammadnejad, P.; Akbari Noghabi, K.

10.1101/2021.07.10.451884 — bioinformatics — Posted on 2021-07-10

2741 BioCantor: a Python library for genomic feature arithmetic in arbitrarily related coordinate systems

Russell, P. H.; Fiddes, I. T.

10.1101/2021.07.09.451743 — bioinformatics — Posted on 2021-07-10

2742 BERTax: taxonomic classification of DNA sequences with Deep Neural Networks

Mock, F.; Kretschmer, F.; Kriese, A.; Böcker, S.; Marz, M.

10.1101/2021.07.09.451778 — bioinformatics — Posted on 2021-07-10

2743 Study of Basic Local Alignment Search Tool (BLAST) and Multiple Sequence Alignment (Clustal- X) of Monoclonal mice/human antibodies

FERRARI, I. V.; PATRIZIO, P.

10.1101/2021.07.09.451785 — bioinformatics — Posted on 2021-07-10

2744 Docking Molecular analysis of potential Drug Paritaprevir against Mycobacterium tuberculosis (Mtb)

FERRARI, I. V.; PATRIZIO, P.

10.1101/2021.07.09.451739 — bioinformatics — Posted on 2021-07-10

2745 Quantitative characterisation of low abundant yeast mitochondrial proteins reveals compensation for haplo-insufficiency in different environments

Manousaki, A.; Bagnall, J.; Spiller, D.; White, M.; Delneri, D.

10.1101/2021.07.09.451775 — biochemistry — Posted on 2021-07-10

2746 Larval zebrafish exhibit collective motion behaviors in constrained spaces

Zaki, H.; Lushi, E.; Severi, K. E.

10.1101/2021.07.09.451841 — animal behavior and cognition — Posted on 2021-07-10

2747 De novo whole-genome assembly of Chrysanthemum makinoi, a key wild ancestor to hexaploid Chrysanthemum

van Lieshout, N.; van Kaauwen, M.; Kodde, L.; Arens, P.; Smulders, M. J. M.; Visser, R. G. F.; Finkers, R.

10.1101/2021.07.09.451814 — genomics — Posted on 2021-07-10

2748 Model Checking via Testing for Direct Effects in Mendelian Randomization and Transcriptome-wide Association Studies

Deng, Y.; Pan, W.

10.1101/2021.07.09.451811 — genetics — Posted on 2021-07-10

2749 On the Etiology of Aesthetic Chills: a Behavioral Genetic Study

Bignardi, G.; Chamberlain, R.; Kevenaar, S. T.; Tamimy, Z.; Boomsma, D. I.

10.1101/2021.07.08.451681 — genetics — Posted on 2021-07-10

2750 Antisense oligonucleotides targeting UBE3A-ATS restore expression of UBE3A by relieving transcriptional interference

Germain, N. D.; Gorka, D.; Drennan, R.; Whipple, A.; Jafar-nejad, P.; Core, L.; Levine, E. S.; Rigo, F.; Chamberlain, S. J.

10.1101/2021.07.09.451826 — genetics — Posted on 2021-07-10

2751 Rapid divergence in vegetative morphology of a wind-pollinated plant between populations at contrasting densities

Tonnabel, J.; David, P.; Pannell, J.

10.1101/2021.07.09.451799 — evolutionary biology — Posted on 2021-07-10

2752 A gene coevolution network provides insight into eukaryotic cellular and genomic structure and function

Steenwyk, J. L.; Phillips, M. A.; Yang, F.; Date, S. S.; Graham, T.; berman, j.; Hittinger, C. T.; Rokas, A.

10.1101/2021.07.09.451830 — evolutionary biology — Posted on 2021-07-10

2753 Contribution of opsins and chromophores to cone pigment variation across populations of Lake Victoria cichlids

Wilwert, E.; Etienne, R. S.; Van de Zande, L.; Maan, M. E.

10.1101/2021.07.09.451730 — evolutionary biology — Posted on 2021-07-10

2754 Evolutionary origins of sexual dimorphism : Lessons from female-limited mimicry in butterflies.

Maisonneuve, L.; Smadi, C.; LLAURENS, V.

10.1101/2021.07.09.451774 — evolutionary biology — Posted on 2021-07-10

2755 A tail of plumage colouration: disentangling geographic, seasonal, and dietary effects on plumage colour in a migratory songbird

Mahoney, S. M.; Reudink, M. W.; Contina, A.; Roberts, K. A.; Schabert, V. T.; Gunther, E. G.; Covino, K. M.

10.1101/2021.07.09.451669 — ecology — Posted on 2021-07-10

2756 Divergent assembly trajectories: a comparison of the plant and soil microbiome with plant communities in a glacier forefield

Junker, R. R.; He, X.; Otto, J.-C.; Ruiz-Hernandez, V.; Hanusch, M.

10.1101/2021.07.09.451772 — ecology — Posted on 2021-07-10

2757 Implications of trade network structure and population dynamics for food security and equality

Fair, K. R.; Bauch, C.; Anand, M.

10.1101/2021.07.08.451671 — ecology — Posted on 2021-07-10

2758 Contribution of Uremia to Ureaplasma-Induced Hyperammonemia

Fleming, D.; Patel, R.

10.1101/2021.07.09.451868 — microbiology — Posted on 2021-07-10

2759 Tributyltin exposure leads to increased adiposity and reduced abundance of leptogenic bacteria in the zebrafish intestine

Gomez de la Torre Canny, S.; Mueller, O.; Craciunescu, C. V.; Blumberg, B.; Rawls, J. F.

10.1101/2021.07.09.451869 — microbiology — Posted on 2021-07-10

2760 Screening and Identification of Lassa Virus Endonuclease-targeting Inhibitors from a Fragment-based Drug Development Library

Lan, X.; Zhang, Y.; Liu, Y.; Guo, J.; Jia, X.; Zhang, M.; Cao, J.; Xiao, G.; Guo, Y.; Wang, W.

10.1101/2021.07.09.451867 — microbiology — Posted on 2021-07-10

2761 Novel low-avidity glypican-3 specific CARTs resist exhaustion and mediate durable antitumor effects against hepatocellular carcinoma

Caraballo-Galva, L.; Hussein, M.; Jiang, X.; Zhang, H.; Mao, R.; Brody, P.; Chi, X.; Peng, Y.; He, A.; Kehinge-Ige, M.; Sadek, R.; Shi, H.; Qiu, X.; He, Y.

10.1101/2021.07.09.451642 — immunology — Posted on 2021-07-10

2762 The PD-1 checkpoint receptor maintains tolerance of self-reactive CD8 T cell in skin

Damo, M.; Cui, C.; William, I.; Hornick, N. I.; Kwok, D.; Clulo, K.; Damsky, W. E.; Leventhal, J. S.; Joshi, N. S.

10.1101/2021.07.09.451765 — immunology — Posted on 2021-07-10

2763 Motor dysfunction in Drosophila melanogaster as a biomarker for developmental neurotoxicity

Cabrita, A.; Medeiros, A. A.; Pereira, T.; Rodrigues, A. S.; Kranendonk, M.; Mendes, C. S.

10.1101/2021.07.09.451676 — neuroscience — Posted on 2021-07-10

2764 TNF-mediated neuroinflammation is linked to neuronal necroptosis in Alzheimer's disease hippocampus

Jayaraman, A.; Htike, T.; James, R.; Picon, C.; Reynolds, R.

10.1101/2021.07.09.451781 — neuroscience — Posted on 2021-07-10

2765 α-Synuclein polymorphism determines oligodendroglial dysfunction

Frieg, B.; Geraets, J. A.; Strohaeker, T.; Dienemann, C.; Mavroeidi, P.; Jung, B. C.; Kim, W.; Lee, S.-J.; Xilouri, M.; Zweckstetter, M.; Schroeder, G. F.

10.1101/2021.07.09.451731 — neuroscience — Posted on 2021-07-10

2766 Atp13a5 Marker Reveals Pericytes of The Central Nervous System in Mice

Guo, X.; Ge, T.; Xia, S.; Wu, H.; Colt, M.; Xie, X.; Zhang, B.; Zeng, J.; Chen, J.-F.; Zhu, D.; Montagne, A.; Gao, F.; Zhao, Z.

10.1101/2021.07.09.451694 — neuroscience — Posted on 2021-07-10

2767 Thalamic state controls timing and synchronization of primary somatosensory cortical representations in the awake mouse

Borden, P. Y.; Wright, N. C.; Morissette, A. R.; Jaeger, D.; Haider, B.; Stanley, G. B.

10.1101/2021.07.09.451656 — neuroscience — Posted on 2021-07-10

2768 Connectome-based Modeling of Mnemonic Discrimination in Younger and Older Adults

Wahlheim, C. N.; Christensen, A. P.; Reagh, Z. M.; Cassidy, B. S.

10.1101/2021.07.09.451777 — neuroscience — Posted on 2021-07-10

2769 Stochastic comparison of synchronization in activator- and repressor-based coupled gene oscillators

Dey, S.; Ul Hasan, A. B. M. S.; Singh, A.; Kurata, H.

10.1101/2021.07.08.451708 — systems biology — Posted on 2021-07-10

2770 Language models enable zero-shot prediction of the effects of mutations on protein function

Meier, J.; Rao, R.; Verkuil, R.; Liu, J.; Sercu, T.; Rives, A.

10.1101/2021.07.09.450648 — synthetic biology — Posted on 2021-07-10

2771 Sleep Medicine Knowledge Among Graduating Medical Students in Lebanon During an Economic and Political Crisis

Aoun, R.; Zibara, V.; Costanian, C.; Attarian, H.; Bahous, S.

10.1101/2021.07.09.451820 — scientific communication and education — Posted on 2021-07-10

2772 Aqueous extract of Phyllanthus niruri protects against severe malaria by blocking erythrocyte invasion and modulating the host immune response

Olawale, J. T.; Bando, H.; Fukuda, Y.; Oluwafemi, I. E.; Kato, K.

10.1101/2021.07.09.451735 — pathology — Posted on 2021-07-10

2773 Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia

Gong, R.; Jiang, F.; Moreland, Z. G.; Reynolds, M. J.; Espinosa de los Reyes, S.; Gurel, P. S.; Shams, A.; Bowl, M. R.; Bird, J. E.; Alushin, G. M.

10.1101/2021.07.09.451843 — biophysics — Posted on 2021-07-10

2774 Cross-linkers at growing microtubule ends generate forces that drive actin transport

Alkemade, C.; Wierenga, H.; Volkov, V. A.; Preciado-Lopez, M.; Akhmanova, A.; ten Wolde, P. R.; Dogterom, M.; Koenderink, G. H.

10.1101/2021.07.09.451744 — biophysics — Posted on 2021-07-10

2775 Development and Validation Molecular Docking Analysis of Human serum albumin (HSA)

FERRARI, I. V.; Patrizio, P.

10.1101/2021.07.09.451789 — bioinformatics — Posted on 2021-07-10

2776 Linking rhizosphere processes across scales: Opinion

Schnepf, A.; Carminati, A.; Ahmed, M.; Ani, M.; Benard, P.; Bentz, J.; Bonkowski, M.; Brax, M.; Diehl, D.; Duddek, P.; Kroener, E.; Javaux, M.; Landl, M.; Lehndorff, E.; Lippold, E.; Lieu, A.; Mueller, C. W.; Oburger, E.; Otten, W.; Phalempin, M.; Prechtel, A.; Schulz, R.; Vanderborght, J.; Vetterlein, D.

10.1101/2021.07.08.451655 — bioengineering — Posted on 2021-07-10

2777 Inhibitory Proteins Block Substrate Access to the Active Site of Bacillus subtilis Intramembrane Metalloprotease SpoIVFB

Olenic, S.; Heo, L.; Feig, M.; Kroos, L.

10.1101/2021.07.09.451828 — biochemistry — Posted on 2021-07-10

2778 Comparing genomic-based estimates of relatedness for use in pedigree-based conservation management

Hauser, S. S.; Galla, S. J.; Steeves, T. E.; Latch, E. K.

10.1101/2021.07.08.451704 — genomics — Posted on 2021-07-10

2779 Environmental differences explain subtle yet detectable genetic structure in a widespread pollinator

Glück, M.; Geue, J. C.; Thomassen, H. A.

10.1101/2021.07.09.451741 — ecology — Posted on 2021-07-10

2780 sMEK1 promotes crosstalk between IRE1 and Akt signaling pathway: Evidence for a novel IRE1/sMEK1/Akt complex

qadri, o.; Bashir, S.; Banday, M.; Hilal, N.; Fazili, K. M.

10.1101/2021.07.09.451832 — cell biology — Posted on 2021-07-10

2781 Cytoplasmic organization promotes protein diffusion

Huang, W. Y. C.; Cheng, X.; Ferrell, J. E.

10.1101/2021.07.09.451827 — biophysics — Posted on 2021-07-10

2782 Transient accumulation and bidirectional movement of KIF13B in primary cilia

Juhl, A. D.; Anvarian, Z.; Berges, J.; Wustner, D.; Pedersen, L. B.

10.1101/2021.07.09.451768 — biophysics — Posted on 2021-07-10

2783 Metabolic state of human blastocysts measured by fluorescence lifetime imaging microscopy

Venturas, M.; Shah, J. S.; Yang, X.; Sanchez, T. H.; Conway, W.; Sakkas, D.; Needleman, D. J.

10.1101/2021.07.09.451821 — cell biology — Posted on 2021-07-10

2784 Cation-chloride cotransporters, Na/K pump, and channels in cell water and ions regulation: in silico and experimental studies of the U937 cells under stopping the pump and during RVD

Vereninov, A. A.; Yurinskaya, V.

10.1101/2021.07.10.451878 — cell biology — Posted on 2021-07-10

2785 Light-dependent THRUMIN1 phosphorylation regulates its association with actin filaments and 14-3-3 proteins

Dwyer, M. E.; Hangarter, R. P.

10.1101/2021.07.09.451853 — cell biology — Posted on 2021-07-10

2786 Vacuolar localization via the N-terminal domain of Sch9 is required for TORC1-dependent phosphorylation and downstream signal transduction

Novarina, D.; Guerra, P.; Milias-Argeitis, A.

10.1101/2021.07.09.451810 — cell biology — Posted on 2021-07-10

2787 Myosin-driven Nucleation of Actin Filaments Drives Stereocilia Development Critical for Hearing

10.1101/2021.07.09.451618 — cell biology — Posted on 2021-07-10

2788 Monoacylglycerol disrupts Golgi structure and perilipin 2 association with lipid droplets

Harris, L.-A. L. S.; Skinner, J. R.; Shew, T. M.; Abumrad, N. A.; Wolins, N.

10.1101/2021.07.09.451829 — cell biology — Posted on 2021-07-10

2789 Multiple roles of heterogeneous nuclear ribonucleoprotein K during skeletal muscle cell differentiation

Hitachi, K.; Kiyofuji, Y.; Nakatani, M.; Tsuchida, K.

10.1101/2021.07.09.451593 — cell biology — Posted on 2021-07-10

2790 Temporal regulation of Pten is essential for retina regeneration in zebrafish

Gupta, S.; Sharma, P.; Choudhary, M.; Premraj, S.; Kaur, S.; Kumar, V.; Ramachandran, R.

10.1101/2021.07.09.451767 — cell biology — Posted on 2021-07-10

2791 Visualizing the pH in Escherichia coli colonies via the sensor protein mCherryEA allows high-throughput screening of mutant libraries

Hartmann, F. S. F.; Weiss, T.; Shen, J.; Smahajcsik, D.; Seibold, G. M.

10.1101/2021.07.08.451719 — microbiology — Posted on 2021-07-10

2792 De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis

Laval, T.; Pedro-Cos, L.; Malaga, W.; Guenin-Mace, L.; Pawlik, A.; Mayau, V.; Yahia-Cherbal, H.; Frigui, W.; Bertrand-Michel, J.; Guilhot, C.; Demangel, C.

10.1101/2021.07.08.451715 — immunology — Posted on 2021-07-10

2793 Loss of TREM2 reduces hyperactivation of progranulin deficient microglia but not lysosomal pathology

Reifschneider, A.; Robinson, S.; van Lengerich, B.; Gnoerich, J.; Logan, T.; Heindl, S.; Vogt, M.; Weidinger, E.; Riedl, L.; Wind, K.; Zatcepin, A.; Haberl, S.; Nuscher, B.; Kleinberger, G.; Klimmt, J.; Goetzl, J.; Liesz, A.; Buerger, K.; Brendel, M.; Levin, J.; Diehl-Schmid, J.; Suh, J.; Di Paolo, G.; Lewcock, J.; Monroe, K.; Paquet, D.; Capell, A.; Haass, C.

10.1101/2021.07.08.451574 — neuroscience — Posted on 2021-07-10

2794 Double nerve transfer to a single target muscle: experimental model in the upper extremity

Luft, M.; Klepetko, J.; Muceli, S.; Ibanez, J.; Tereshenko, V.; Festin, C.; Laengle, G.; Politikou, O.; Maierhofer, U.; Farina, D.; Aszmann, O. C.; Bergmeister, K. D.

10.1101/2021.07.09.451759 — neuroscience — Posted on 2021-07-10

2795 Multi-environment QTL analysis delineates a major locus associated with homoeologous exchanges for water-use efficiency and seed yield in allopolyploid Brassica napus

Raman, H.; Raman, R.; Pirathiban, R.; McVittie, B.; Sharma, N.; Liu, S.; Qiu, Y.; Zhu, A.; Killian, A.; Cullis, B.; Farquhar, G.; Williams, H. S.; White, R.; Tabah, D.; Easton, A.; Zhang, Y.

10.1101/2021.07.08.451711 — plant biology — Posted on 2021-07-10

2796 Thioredoxin reductase controls the capacity of peroxiredoxins to limit mitochondrial H2O2 release

Hoehne, M. N.; Jacobs, L. J.; Lapacz, K. J.; Murschall, L. M.; Marker, T.; Morgan, B.; Fricker, M.; Belousov, V.; Riemer, J.

10.1101/2021.07.08.451718 — biochemistry — Posted on 2021-07-10

2797 Complex Mutation Profiles in Mismatch Repair and Ribonucleotide Reductase Mutations Reveal Novel Repair Substrate Specificity of MutS Homolog (MSH) Complexes

Lamb, N. A.; Bard, J.; Loll-Krippleber, R.; Brown, G. W.; Surtees, J. A.

10.1101/2021.06.30.450577 — genetics — Posted on 2021-07-10

2798 Phylogenetic network analysis revealed the recombinant origin of the SARS-CoV-2 VOC202012/01 (B.1.1.7) variant first discovered in U.K.

Xie, X.; Lewis, T.-J.; Green, N.; Wang, Z.

10.1101/2021.06.24.449840 — microbiology — Posted on 2021-07-10

2799 The Consequences of Differential Origin Licensing Dynamics in Distinct Chromatin Environments

Mei, L.; Kedziora, K. M.; Song, E.-a.; Purvis, J. E.; Cook, J. G.

10.1101/2021.06.28.450210 — molecular biology — Posted on 2021-07-10

2800 Behaviorally emergent hippocampal place maps remain stable during memory recall

Zemla, R.; Moore, J. J.; Basu, J.

10.1101/2021.07.08.451449 — neuroscience — Posted on 2021-07-10

2801 Cytokinin oxidase/dehydrogenase family genes exhibit functional divergence and overlap in rice growth and development

Rong, C.; Liu, Y.; Chang, Z.; Liu, Z.; Ding, Y.; Ding, C.

10.1101/2021.05.09.443313 — plant biology — Posted on 2021-07-10

2802 Structural modeling of the hERG potassium channel and associated drug interactions

Maly, J.; Emigh, A. M.; DeMarco, K. R.; Furutani, K.; Sack, J. T.; Clancy, C. E.; Vorobyov, I.; Yarov-Yarovoy, V.

10.1101/2021.07.08.451699 — biophysics — Posted on 2021-07-10

2803 Deep parallel characterization of AAV tropism and AAV-mediated transcriptional changes via single-cell RNA sequencing

Brown, D.; Altermatt, M.; Dobreva, T.; Chen, S.; Wang, A.; Thomson, M.; Gradinaru, V.

10.1101/2021.06.25.449955 — bioengineering — Posted on 2021-07-10

2804 Differential fate of acellular vascular scaffolds in vivo involves macrophages and T-cell subsets

Banerjee, D.; Nayakawde, N. B.; Antony, D.; Deshmukh, M.; Ghosh, S.; Sihlbom, C.; Berger, E.; Ul Haq, U.; Olausson, M.

10.1101/2020.11.21.392654 — bioengineering — Posted on 2021-07-10

2805 Desiccation-induced fibrous condensation of CAHS protein from an anhydrobiotic tardigrade

Yagi-Utsumi, M.; Aoki, K.; Watanabe, H.; Song, C.; Nishimura, S.; Satoh, T.; Yanaka, S.; Ganser, C.; Tanaka, S.; Schnapka, V.; Goh, E. W.; Furutani, Y.; Murata, K.; Uchihashi, T.; Arakawa, K.; Kato, K.

10.1101/2021.06.22.449423 — biochemistry — Posted on 2021-07-10

2806 Identification of general acid catalyst for the ATPase activity of Lynch syndrome-related MutL homologs

Fukui, K.; Fujii, Y.; Yano, T.

10.1101/2021.07.09.451751 — biochemistry — Posted on 2021-07-10

2807 SAXS analysis of the intrinsic tenase complex bound to lipid nanodisc highlights intermolecular contacts between factors VIIIa/IXa

Childers, K. C.; Peters, S. C.; Lollar, P.; Spencer, H. T.; Doering, C. B.; Spiegel, P. C.

10.1101/2021.07.09.451823 — biochemistry — Posted on 2021-07-10

2808 CTP and parS coordinate ParB partition complex dynamics and ParA-ATPase activation for ParABS-mediated DNA partitioning

Taylor, J. A.; Seol, Y.; Budhathoki, J.; Neuman, K. C.; Mizuuchi, K.

10.1101/2021.01.24.427996 — cell biology — Posted on 2021-07-10

2809 Campylobacter jejuni trigger signaling through host cell focal adhesions to inhibit cell motility and impede wound repair

Klappenbach, C. M.; Negretti, N. M.; Aaron, J.; Chew, T.-L.; Konkel, M. E.

10.1101/2021.05.14.443831 — microbiology — Posted on 2021-07-10

2810 Serotonergic neural network related to behavioral inhibition system

Kojima, K.; Hirano, S.; Kimura, Y.; Seki, C.; Ikoma, Y.; Takahata, K.; Ito, T.; Yokokawa, K.; Hashimoto, H.; Kawamura, K.; Zhang, M.-R.; Ito, H.; Higuchi, M.; Kuwabara, S.; Suhara, T.; Yamada, M.

10.1101/2021.07.09.451787 — neuroscience — Posted on 2021-07-10

2811 Deficiency of the paternally inherited gene Magel2 alters the development of separation-induced vocalization and maternal behavior in mice

Bosque Ortiz, G. M.; Santana, G. M.; Dietrich, M. O.

10.1101/2021.04.01.438102 — neuroscience — Posted on 2021-07-10

2812 Subspace alignment as a mechanism for binding

Fine, J. M.; Yoo, S. B. M.; Ebitz, B.; Hayden, B.

10.1101/2021.07.07.451472 — neuroscience — Posted on 2021-07-10

2813 Disrupted microglial iron homeostasis in progressive multiple sclerosis

Proto, J. D.; Zhang, M.; Ryan, S.; Yao, X.; Huang, Y.; Chang, Y.-C.; Dufault, M.; Christie, E.; Chomyk, A.; Saleh, J.; Blazier, A.; Sancho, J.; Hammond, T.; Trapp, B.; Ofengeim, D.

10.1101/2021.05.09.443127 — neuroscience — Posted on 2021-07-10

2814 Optimizing interneuron circuits for compartment-specific feedback inhibition

Keijser, J.; Sprekeler, H.

10.1101/2020.11.17.386920 — neuroscience — Posted on 2021-07-10

2815 Single-cell profiling of the human primary motor cortex in ALS and FTLD

Pineda, S. S.; Lee, H.; Fitzwalter, B. E.; Mohammadi, S.; Pregent, L. J.; Gardashli, M. E.; Mantero, J.; Engelberg-Cook, E.; DeJesus-Hernandez, M.; van Blitterswijk, M.; Pottier, C.; Rademakers, R.; Oskarsson, B.; Shah, J. S.; Petersen, R. C.; Graff-Radford, N. R.; Boeve, B. F.; Knopman, D. S.; Josephs, K. A.; DeTure, M.; Murray, M. E.; Dickson, D. W.; Heiman, M.; Belzil, V. V.; Kellis, M.

10.1101/2021.07.07.451374 — neuroscience — Posted on 2021-07-10

2816 End-to-end computational approach to the design of RNA biosensors for miRNA biomarkers of cervical cancer

Baabu, P. R. S.; Srinivasan, S.; Nagarajan, S.; Muthamilselvan, S.; Suresh, R. R.; Selvi, T.; Palaniappan, A.

10.1101/2021.07.09.451282 — synthetic biology — Posted on 2021-07-10

2817 Quantifying the potential for red blood cell β-adrenergic sodium-proton exchangers to protect oxygen transport in hypoxic and hypercapnic white seabass

Harter, T. S.; Clifford, A. M.; Tresguerres, M.

10.1101/2021.04.28.441819 — physiology — Posted on 2021-07-10

2818 Dysregulated myogenesis and autophagy in genetically induced pulmonary emphysema

Balnis, J.; Drake, L. A.; Singer, D. V.; Vincent, C.; Korponay, T. C.; D'Armiento, J. M.; Lee, C. G.; Elias, J. A.; Singer, H. A.; Jaitovich, A.

10.1101/2021.07.08.450201 — physiology — Posted on 2021-07-10

2819 Stress relaxation amplitude of hydrogels determines migration, proliferation, and morphology of cells in 3-D

Hazur, J.; Endrizzi, N.; Schubert, D. W.; Boccaccini, A. R.; Fabry, B.

10.1101/2021.07.08.451608 — biophysics — Posted on 2021-07-09

2820 ACE: Explaining cluster from an adversarial perspective

Lu, Y. Y.; Yu, T.; Bonora, G.; Noble, W. S.

10.1101/2021.02.08.428881 — bioinformatics — Posted on 2021-07-10

2821 Structural and mechanistic insight into CRISPR-Cas9 inhibition by anti-CRISPR protein AcrIIC4

Hwang, S.; Pan, C.; Garcia, B.; Davidson, A. R.; Moraes, T. F.; Maxwell, K. L.

10.1101/2021.07.09.451512 — biochemistry — Posted on 2021-07-10

2822 The 3D enhancer network of the developing T cell genome is controlled by SATB1

Zelenka, T.; Klonizakis, A.; Tsoukatou, D.; Franzenburg, S.; Tzerpos, P.; Papamatheakis, D. A.; Tzonevrakis, I. R.; Nikolaou, C.; Plewczynski, D.; Spilianakis, C.

10.1101/2021.07.09.451769 — molecular biology — Posted on 2021-07-09

2823 SUPT3H-less SAGA coactivator can assemble and function without significantly perturbing RNA polymerase II transcription in mammalian cells

Fischer, V.; Scheer, E.; Lata, E.; Morlet, B.; Plassard, D.; Vincent, S. D.; Helmlinger, D.; Devys, D.; Tora, L.

10.1101/2021.07.09.451791 — molecular biology — Posted on 2021-07-09

2824 Single molecule studies reveal branched pathways for activator-dependent assembly of RNA polymerase II pre-initiation complexes

Baek, I.; Friedman, L. J.; Gelles, J.; Buratowski, S.

10.1101/2021.06.20.449130 — molecular biology — Posted on 2021-07-09

2825 Co-cultivation of the anaerobic fungus Caecomyces churrovis with Methanobacterium bryantii enhances transcription of carbohydrate binding modules

Brown, J. L.; Swift, C. L.; Mondo, S.; Seppala, S.; Salamov, A.; Singan, V.; Henrissat, B.; Henske, J. K.; Lee, S.; He, G.; Yan, M.; Barry, K.; Grigoriev, I. V.; O'Malley, M. A.

10.1101/2021.07.09.451685 — microbiology — Posted on 2021-07-09

2826 A combination of metagenomic and cultivation approaches reveals hypermutator phenotypes within Vibrio cholerae infected patients

Levade, I.; Khan, A. I.; Chowdhury, F.; Calderwood, S. B.; Ryan, E. T.; Harris, J. B.; LaRocque, R. C.; Bhuiyan, T. R.; Qadri, F.; Weil, A. A.; Shapiro, B. J.

10.1101/2020.10.11.333682 — microbiology — Posted on 2021-07-09

2827 Independent host- and bacterium-based determinants protect a model symbiosis from phage predation

Lynch, J. B.; Bennett, B. D.; Merrill, B. D.; Ruby, E. G.; Hryckowian, A. J.

10.1101/2021.07.09.451802 — microbiology — Posted on 2021-07-10

2828 Experimental evolution of Bacillus subtilis on Arabidopsis thaliana roots reveals fast adaptation and improved root colonization in the presence of soil microbes

Nordgaard, M.; Blake, C.; Maroti, G.; Strube, M. L.; Kovacs, A. T.

10.1101/2021.07.09.451762 — microbiology — Posted on 2021-07-10

2829 Sensory coding and causal impact of mouse cortex in a visual decision

Zatka-Haas, P.; Steinmetz, N. A.; Carandini, M.; Harris, K. D.

10.1101/501627 — neuroscience — Posted on 2021-07-09

2830 The cerebellum encodes and influences the initiation and termination of discontinuous movements

Christie, J. M.; Gaffield, M. A.

10.1101/2021.06.24.449622 — neuroscience — Posted on 2021-07-09

2831 Structural covariance of amygdala subregions is associated with trait aggression and endogenous testosterone in healthy individuals

Gottlich, M.; Buades Rotger, M.; Wiechert, J.; Beyer, F.; Kramer, U. M.

10.1101/2021.07.09.451771 — neuroscience — Posted on 2021-07-09

2832 Modulation in Alpha Band Activity Reflects Syntax Composition: An MEG Study of Minimal Syntactic Binding

Hardy, S. M.; Jensen, O.; Wheeldon, L.; Mazaheri, A.; Segaert, K.

10.1101/2021.07.09.451797 — neuroscience — Posted on 2021-07-09

2833 Mechanosensory input during circuit formation shapes Drosophila motor behavior through Patterned Spontaneous Network Activity

Carreira-Rosario, A.; York, R. A.; Choi, M.; Doe, C. Q.; Clandinin, T. R.

10.1101/2021.03.21.436277 — neuroscience — Posted on 2021-07-09

2834 Resilience in a Natural Model of Metabolic Dysfunction Through Changes in Longevity and Ageing-Related Metabolites

Medley, J. K.; Persons, J.; Biswas, T.; Olsen, L.; Peuss, R.; Krishnan, J.; Xiong, S.; Rohner, N.

10.1101/2020.10.27.358077 — systems biology — Posted on 2021-07-09

2835 Cellular-level phenotyping of tumor-immune microenvironment (TiME) in patients in vivo reveals distinct inflammation and endothelial anergy signatures

Sahu, A.; Tembo, T.; Kose, K.; Santella, A.; Alfonso, A.; Li, M.; Cordova, M.; Gill, M.; Fox, C.; Gonzalez, S.; Wang, A. W.; Kurtansky, N. R.; Chandrani, P.; Kumar, P.; Yin, S.; Jilani, H.; Mehta, P.; Navarrete-Dechent, C.; Peterson, G.; King, K.; Dusza, S.; Yang, N.; Liu, S.; Phillip, W.; Rossi, A.; Halpern, A.; Deng, L.; Pulitzer, M.; Marghoob, A.; Chen, C.-S. J.; Rajadhyaksha, M.

10.1101/2021.06.10.447835 — cancer biology — Posted on 2021-07-09

2836 SUFI: An automated approach to spectral unmixing of fluorescent multiplex images captured in mouse and postmortem human brain tissues

Sadashivaiah, V.; Tippani, M.; Page, S. C.; Kwon, S. H.; Bach, S. V.; Bharadwaj, R. A.; Hyde, T. M.; Kleinman, J. E.; Jaffe, A. E.; Maynard, K. R.

10.1101/2021.01.28.428639 — bioinformatics — Posted on 2021-07-09

2837 Non-Newtonian Patient-specific Simulations of Left Atrial Hemodynamics

Gonzalo, A.; Garcia-Villalba, M.; Rossini, L.; Duran, E.; Vigneault, D.; Martinez-Legazpi, P.; Flores, O.; Bermejo, J.; McVeigh, E.; Kahn, A.; del Alamo, J. C.

10.1101/2021.06.24.449801 — bioengineering — Posted on 2021-07-09

2838 Neural encoding of phrases and sentences in spoken language comprehension

Bai, F.; Meyer, A. S.; Martin, A. E.

10.1101/2021.07.09.451747 — neuroscience — Posted on 2021-07-09

2839 Global patterns of subgenome evolution in organelle-targeted genes of sixallotetraploid angiosperms

Sharbrough, J.; Conover, J.; Fernandes Gyorfy, M.; Grover, C.; Miller, E. R.; Wendel, J. F.; Sloan, D. B.

10.1101/2021.07.09.451712 — evolutionary biology — Posted on 2021-07-09

2840 Using Domain-Knowledge to Assist Lead Discovery in Early-Stage Drug Design

Dash, T.; Srinivasan, A.; Vig, L.; Roy, A.

10.1101/2021.07.09.451519 — molecular biology — Posted on 2021-07-09

2841 In silico proof of principle of machine learning-based antibody design at unconstrained scale

Akbar, R.; Robert, P. A.; Weber, C. R.; Widrich, M.; Frank, R.; Pavlovic, M.; Scheffer, L.; Chernigovskaya, M.; Snapkov, I.; Slabodkin, A.; Mehta, B. B.; Miho, E.; Lund-Johansen, F.; Andersen, J. T.; Hochreiter, S.; Haff, I. H.; Klambauer, G.; Sandve, G. K.; Greiff, V.

10.1101/2021.07.08.451480 — immunology — Posted on 2021-07-09

2842 Lipopolysaccharide-induced neuroinflammation disrupts functional connectivity and community structure in primary cortical microtissues

Atherton, E.; Brown, S.; Papiez, E.; Restrepo, M. I.; Borton, D. A.

10.1101/2021.07.08.451705 — neuroscience — Posted on 2021-07-09

2843 Behaviorally emergent hippocampal place maps remain stable during memory recall

Zemla, R.; Moore, J. J.; Basu, J.

10.1101/2021.07.08.451449 — neuroscience — Posted on 2021-07-09

2844 Organization of cortical and thalamic input to inhibitory neurons in mouse motor cortex

Okoro, S. U.; Goz, R. U.; Njeri, B. W.; Harish, M.; Ruff, C. F.; Ross, S. E.; Gerfen, C. R.; Hooks, B. M.

10.1101/2021.07.08.451716 — neuroscience — Posted on 2021-07-09

2845 Investigating brain mechanisms underlying natural reading by co-registering eye tracking with combined EEG and MEG

Weiss, B.; Dreyer, F.; Fonteneau, E.; van Casteren, M.; Hauk, O.

10.1101/2021.07.09.451139 — neuroscience — Posted on 2021-07-09

2846 Luminance and contrast of images in the THINGS database

Harrison, W. J.

10.1101/2021.07.08.451706 — neuroscience — Posted on 2021-07-09

2847 Curcumin micronization by supercritical fluid: in vitro and in vivo biological relevance

Sachett, A.; Gallas-Lopes, M.; Benvenutti, R.; Marcon, M.; Aguiar, G. P. S.; Oliveira, J. V.; Herrmann, A. P.; Siebel, A. M.; Piato, A.

10.1101/2021.07.08.451641 — neuroscience — Posted on 2021-07-09

2848 Your head is there to move you around: Goal-driven models of the primate dorsal pathway

Mineault, P. J.; Bakhtiari, S.; Richards, B. A.; Pack, C. C.

10.1101/2021.07.09.451701 — neuroscience — Posted on 2021-07-09

2849 Obtaining Spatially Resolved Tumor Purity Maps Using Deep Multiple Instance Learning In A Pan-cancer Study

Oner, M. U.; Chen, J.; Revkov, E.; James, A.; Heng, S. Y.; Kaya, A. N.; Alvarez, J. J. S.; Takano, A.; Cheng, X. M.; Lim, T. K. H.; Tan, D. S. W.; Zhai, W.; Jacobsen Skanderup, A.; Sung, W.-K.; Lee, H. K.

10.1101/2021.07.08.451443 — cancer biology — Posted on 2021-07-09

2850 CALIPER: A software for blood-free parametric Patlak mapping using PET/MRI input function.

Dassanayake, P.; Cui, L.; Finger, E.; Kewin, M.; Hadaway, J.; Soddu, A.; Jakoby, B.; Zuehlsdorff, S.; St Lawrence, K. S.; Moran, G.; Anazodo, U. C.

10.1101/2021.07.08.451713 — bioinformatics — Posted on 2021-07-09

2851 Photoredox-catalyzed decarboxylative C-terminal differentiation for bulk and single molecule proteomics

Zhang, L.; Floyd, B. M.; Chilamari, M.; Mapes, J.; Swaminathan, J.; Bloom, S.; Marcotte, E. M.; Anslyn, E. V.

10.1101/2021.07.08.451692 — biochemistry — Posted on 2021-07-09

2852 An Empirical Bayes Approach to Estimating Dynamic Models of Co-regulated Gene Expression

Venkatraman, S.; Basu, S.; Clark, A. G.; Delbare, S. Y. N.; Lee, M. H.; Wells, M. T.

10.1101/2021.07.08.451684 — genomics — Posted on 2021-07-09

2853 Multifactorial chromatin regulatory landscapes at single cell resolution

Meers, M. P.; Janssens, D. H.; Henikoff, S.

10.1101/2021.07.08.451691 — genomics — Posted on 2021-07-09

2854 Unraveling patterns of disrupted gene expression across a complex tissue

Hunnicutt, K. E.; Good, J. M.; Larson, E. L.

10.1101/2021.07.08.451646 — evolutionary biology — Posted on 2021-07-09

2855 Critical genetic program for Drosophila imaginal disc regeneration revealed by single-cell analysis

Worley, M. I.; Everetts, N.; Yasutomi, R.; Yosef, N.; Hariharan, I. K.

10.1101/2021.07.08.451678 — developmental biology — Posted on 2021-07-09

2856 A photoactivable natural product with broad antiviral activity against enveloped viruses including highly pathogenic coronaviruses

Meunier, T.; Desmarets, L.; Bordage, S.; Bamba, M.; Hervouet, K.; Rouille, Y.; Francois, N.; Decossas, M.; Tra Bi, F. H.; Lambert, O.; Dubuisson, J.; Belouzard, S.; Sahpaz, S.; Seron, K.

10.1101/2021.07.09.451770 — microbiology — Posted on 2021-07-09

2857 Therapeutic efficacy of CT-P59 against P.1 variant of SARS-CoV-2

Lee, S.-Y.; Ryu, D.-K.; Kang, b.; Noh, H.; Kim, J.; Seo, J.-M.; Kim, C.; Baalen, C. v.; Tijsma, A. S.; Chung, H.-Y.; Lee, M.-H.; Oh, S.-S.; Choi, J.-a.; Song, M.; Kwon, K.-S.

10.1101/2021.07.08.451696 — microbiology — Posted on 2021-07-09

2858 Reduced neutralization of SARS-CoV-2 B.1.617 variant by inactivated and RBD-subunit vaccine

Hu, J.; Wei, X.-y.; Xiang, J.; Peng, P.; Xu, F.-l.; Wu, K.; Luo, F.-y.; Jin, A.-s.; Fang, L.; Liu, B.-z.; Wang, K.; Tang, N.; Huang, A.

10.1101/2021.07.09.451732 — microbiology — Posted on 2021-07-09

2859 Impact of temperature on the affinity of SARS-CoV-2 Spike for ACE2

Prevost, J.; Richard, J.; Gasser, R.; Ding, S.; Fage, C.; Anand, S. P.; Adam, D.; Gupta Vergara, N.; Tauzin, A.; Benlarbi, M.; Gong, S. Y.; Goyette, G.; Prive, A.; Moreira, S.; Charest, H.; Roger, M.; Mothes, W.; Pazgier, M.; Brochiero, E.; Boivin, G.; Abrams, C. F.; Schon, A.; Finzi, A.

10.1101/2021.07.09.451812 — microbiology — Posted on 2021-07-09

2860 Persistent autism-relevant phenotype produced by in utero and lactational exposure of female mice to the commercial PBDE mixture, DE-71

Kozlova, E. V.; Valdez, M. C.; Denys, M. E.; Bishay, A. E.; Krum, J. M.; Rabbani, K. M.; Carrillo, V.; Gonzalez, G. M.; Lampel, G.; Tran, J. D.; Vazquez, B. M.; Anchondo, L. M.; Uddin, S. A.; Huffman, N. M.; Monarrez, E.; Olomi, D. S.; Chinthirla, B. D.; Hartman, R. E.; Kodavanti, P. S. R.; Chompre, G.; Phillips, A. L.; Stapleton, H. M.; Henkelmann, B.; Schramm, K.-W.; Curras-Collazo, M. C.

10.1101/2021.07.08.451690 — neuroscience — Posted on 2021-07-09

2861 Dysregulated myogenesis and autophagy in genetically induced pulmonary emphysema

Balnis, J.; Drake, L. A.; Singer, D. V.; Vincent, C.; Korponay, T. C.; D'Armiento, J. M.; Lee, C. G.; Elias, J. A.; Singer, H. A.; Jaitovich, A.

10.1101/2021.07.08.450201 — physiology — Posted on 2021-07-09

2862 The mitochondrial Na+/Ca2+ exchanger, NCLX, mediates PDE2 dependent neuronal survival and learning

Rozenfeld, M.; Savic Azoulay, I.; Ben Kasus Nissim, T.; Stavsky, A.; Hershfinkel, M.; Kofman, O.; Sekler, I.

10.1101/2021.07.08.451717 — physiology — Posted on 2021-07-09

2863 Hepatoprotective effects of Aureobasidium pullulans derived Beta 1,3-1,6 biological response modifier glucans in a STAM- animal model of non-alcoholic steatohepatitis

Ikewaki, N.; Kurosawa, G.; Iwasaki, M.; Preethy, S.; Dedeepiya, V. D.; Vaddi, S.; Senthilkumar, R.; Levy, G. A.; Abraham, S. J.

10.1101/2021.07.08.451700 — pharmacology and toxicology — Posted on 2021-07-09

2864 Dimensionality reduction and data integration for scRNA-seq data based on integrative hierarchical Poisson factorisation

Wong, T.; Barahona, M.

10.1101/2021.07.08.451664 — bioinformatics — Posted on 2021-07-09

2865 Multi-morph eco-evolutionary dynamics in structured populations

Lion, S.; Boots, M.; Sasaki, A.

10.1101/2021.07.08.451558 — evolutionary biology — Posted on 2021-07-09

2866 Phylotranscriptomics reveals discordance in the phylogeny of Hawaiian Drosophila and Scaptomyza (Diptera: Drosophilidae)

Church, S. H.; Extavour, C. G.

10.1101/2021.07.08.451653 — evolutionary biology — Posted on 2021-07-09

2867 Microbiome divergence of marine gastropod species separated by the Isthmus of Panama

Neu, A. T.; Torchin, M. E.; Allen, E. E.; Roy, K.

10.1101/2021.07.08.451645 — ecology — Posted on 2021-07-09

2868 Investigating Regional Specificity of Alzheimers Disease Pathology in the 5xFAD Mouse Model

Gyan, A.; Glass, E. D.; Stevenson, T.; Murphy, G. G.; Moore, S.

10.1101/2021.07.08.441803 — neuroscience — Posted on 2021-07-09

2869 Instrumental aversion coding in the basolateral amygdala and its reversion by a benzodiazepine

Jean-Richard-dit-Bressel, P.; Tran, J.; Didachos, A.; McNally, G. P.

10.1101/2021.07.08.451726 — neuroscience — Posted on 2021-07-09

2870 Cell-type specific transcriptional adaptations of nucleus accumbens interneurons to amphetamine

Gallegos, D. A.; Minto, M.; Liu, F.; Hazlett, M. F.; Yousefzadeh, S. A.; Bartelt, L. C.; West, A. E.

10.1101/2021.07.08.451674 — neuroscience — Posted on 2021-07-09

2871 Time-resolved structure-function coupling in brain networks

Liu, Z.-Q.; Vazquez-Rodriguez, B.; Spreng, R. N.; Bernhardt, B.; Betzel, R. F.; Misic, B.

10.1101/2021.07.08.451672 — neuroscience — Posted on 2021-07-09

2872 A specific relationship between musical sophistication and auditory working memory

Lad, M.; Billig, A. J.; Kumar, S.; Griffiths, T.

10.1101/2021.07.08.451659 — neuroscience — Posted on 2021-07-09

2873 The Ubiquitous Vigilance Signal in fMRI Time Series Data

Gonzalez-Castillo, J.; Fernandez, I.; Handwerker, D. A.; Bandettini, P. A.

10.1101/2021.07.08.451677 — neuroscience — Posted on 2021-07-09

2874 NGS comparison of Downy and Powdery mildew resistance genomic regions between 'Regent' and 'Red Globe'

van Heerden, C. J.; Burger, P.; Burger, J. T.; Prins, R.

10.1101/2021.07.08.451625 — genetics — Posted on 2021-07-09

2875 Knock-in tagging in zebrafish facilitated by insertion into non-coding regions

Levic, D. S.; Yamaguchi, N.; Wang, S.; Knaut, H.; Bagnat, M.

10.1101/2021.07.08.451679 — developmental biology — Posted on 2021-07-09

2876 Improved prediction of behavioral and neural similarity spaces using pruned DNNs

Tarigopula, H. P.; Fairhall, S. L.; Hasson, U.

10.1101/2021.07.08.451521 — neuroscience — Posted on 2021-07-09

2877 Standardizing workflows in imaging transcriptomics with the abagen toolbox

Markello, R.; Arnatkeviciute, A.; Poline, J.-B.; Fulcher, B. D.; Fornito, A.; Misic, B.

10.1101/2021.07.08.451635 — neuroscience — Posted on 2021-07-09

2878 Flexible utilization of spatial- and motor-based codes for the storage of visuo-spatial information

Henderson, M. M.; Rademaker, R. L.; Serences, J. T.

10.1101/2021.07.08.451663 — neuroscience — Posted on 2021-07-09

2879 Ovarian cysts and granulosa cell tumors develop after sublethal total body irradiation in mice

Xiao, S.; Xiao, Y.; Xu, X.; Zhang, W.; Murph, M. M.; Manley, N. R.

10.1101/2021.07.08.450892 — cancer biology — Posted on 2021-07-09

2880 Host cell membrane capture by the SARS CoV-2 spike protein fusion intermediate

Su, R.; Zeng, J.; O'Shaughnessy, B.

10.1101/2021.04.09.439051 — biophysics — Posted on 2021-07-09

2881 Non-equilibrium conditions inside rock pores drive fission, maintenance and selection of coacervate protocells

Ianeselli, A.; Tetiker, D.; Stein, J.; Kuehnlein, A.; Mast, C.; Braun, D.; Tang, T.-Y. D.

10.1101/2021.07.08.451414 — biophysics — Posted on 2021-07-09

2882 RESEPT: tissue architecture inference and visualization from spatially resolved transcriptomics

Chang, Y.; He, F.; Wang, J.; Chen, S.; Li, J.; Liu, J.; Yu, Y.; Su, L.; Ma, A.; Allen, C.; Lin, Y.; Sun, S.; Liu, B.; Otero, J.; Chung, D.; Fu, H.; Li, Z.; Xu, D.; Ma, Q.

10.1101/2021.07.08.451210 — bioinformatics — Posted on 2021-07-09

2883 Glycocalyx engineering with heparan sulfate mimetics attenuates Wnt activity during adipogenesis to promote glucose uptake and metabolism.

Trieger, G.; Pessentheiner, A.; Purcell, S.; Green, C. R.; DeForest, N.; Willert, K.; Majithia, A.; Metallo, C.; Godula, K.; Gordts, P.

10.1101/2021.07.08.451710 — cell biology — Posted on 2021-07-09

2884 Centriole distal-end proteins CP110 and Cep97 influence cartwheel growth at the proximal-end of centrioles

Aydogan, M. G.; Hankins, L. E.; Steinacker, T. L.; Mofatteh, M.; Saurya, S.; Wainman, A.; Wong, S. S.; Lu, X.; Zhou, F. Y.; Raff, J. W.

10.1101/2021.07.08.451650 — cell biology — Posted on 2021-07-09

2885 Persistence of SARS CoV-2 S1 Protein in CD16+ Monocytes in Post-Acute Sequelae of COVID-19 (PASC) Up to 15 Months Post-Infection

10.1101/2021.06.25.449905 — immunology — Posted on 2021-07-09

2886 Rationally designed immunogens enable immune focusing to the SARS-CoV-2 receptor binding motif

Hauser, B. M.; Sangesland, M.; St. Denis, K. J.; Windsor, I. W.; Feldman, J.; Lam, E. C.; Kannegieter, T.; Balazs, A. B.; Lingwood, D.; Schmidt, A. G.

10.1101/2021.03.15.435440 — immunology — Posted on 2021-07-09

2887 Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses

Feldman, J.; Bals, J.; Altomare, C.; Denis, K. S.; Lam, E. C.; Hauser, B. M.; Ronsard, L.; Sangesland, M.; Moreno, T. B.; Okonkwo, V.; Hartojo, N.; Balazs, A. B.; Bajic, G.; Lingwood, D.; Schmidt, A. G.

10.1101/2021.02.02.429458 — immunology — Posted on 2021-07-09

2888 Cerebellar Control of a Unitary Head Direction Sense

Fallahnezhad, M.; Le Mero, J.; Zenelaj, X.; Vincent, J.; Rochefort, C.; Rondi-Reig, L.

10.1101/2021.07.08.451624 — neuroscience — Posted on 2021-07-09

2889 Cryo-EM structure of alpha-synuclein fibrils amplified by PMCA from PD and MSA patient brains

Burger, D.; Fenyi, A.; Bousset, L.; Stahlberg, H.; Melki, R.

10.1101/2021.07.08.451588 — neuroscience — Posted on 2021-07-09

2890 Identifying cellular-to-phenotype associations by elucidating hierarchical relationships in high-dimensional cytometry data

Chan, A. S.; Jiang, W.; Blyth, E.; Yang, J. Y. H.; Patrick, E.

10.1101/2021.07.08.451609 — bioinformatics — Posted on 2021-07-09

2891 A Mouse Model of Brittle Cornea Syndrome caused by mutation in Zfp469.

Stanton, C. M.; Findlay, A. S.; Drake, C.; Mustafa, M. Z.; Gautier, P.; McKie, L.; Jackson, I. J.; Vitart, V.

10.1101/2021.07.08.451591 — genetics — Posted on 2021-07-09

2892 Rapid evolution of the functionally conserved gap gene giant in Drosophila

Chang, W.; Matute, D. R.; Kreitman, M.

10.1101/2021.07.08.451553 — evolutionary biology — Posted on 2021-07-09

2893 Non-invasive imaging of gene expression and protein secretion dynamics in living mice

Nourse, J.; Tokalov, S.; Khan, E.; Khokhar, S.; Schott, L. K.; Hinz, L.; Eder, L.; Arnold-Schild, D.; Probst, H. C.; Danckwardt, S.

10.1101/2021.07.08.451623 — cell biology — Posted on 2021-07-09

2894 Lung adenocarcinoma cell-derived exosomal miR-328 promote osteoclastogenesis by targeting Nrp2

Zhang, C. C.; Qin, J.; Yang, L.; Zhu, Z.; Qian, X.; Yang, J.; Su, W.; Wang, F.; Chen, W.; Deng, H.; Wang, Z.

10.1101/2021.07.08.451611 — cancer biology — Posted on 2021-07-09

2895 Heterogeneous substrate binding in a glutamate transporter homologue

Reddy, K. D.; Ciftci, D.; Scopelliti, A.; Boudker, O.

10.1101/2021.07.08.451670 — biophysics — Posted on 2021-07-09

2896 MMMVI: Detecting SARS-CoV-2 Variants of Concern in Metagenomic Wastewater Samples

Barker, D. O. R.; Buchanan, C. J.; Landgraff, C.; Taboada, E. N.

10.1101/2021.06.14.448421 — bioinformatics — Posted on 2021-07-09

2897 Short-term diet intervention alters the small non-coding RNA (sncRNA) landscape of human sperm

Vaz, C.; Kermack, A. J.; Burton, M.; Tan, P. F.; Huan, J.; Yoo, T. P.; Donnelly, K.; Wellstead, S. J.; Fisk, H. L.; Houghton, F. D.; Lewis, S.; Chong, Y. S.; Gluckman, P. D.; Cheong, Y.; Macklon, N. S.; Calder, P. C.; Dutta, A.; Godfrey, K. M.; Kumar, P.; Lillycrop, K. A.; Karnani, N.

10.1101/2021.07.08.451257 — bioinformatics — Posted on 2021-07-09

2898 Therapeutic targeting of SETD2-deficient cancer cells with the small-molecule compound RITA

Lopez, K. A.; Sarkar, S.; Seraia, E.; Toffanin, C.; Cooper, C.; Challoumas, M.; Okonjo, F. A.; Jones, G. D. D.; Buffa, F.; Ebner, D.; Humphrey, T. C.

10.1101/2021.07.08.451582 — cell biology — Posted on 2021-07-09

2899 Absolute quantitation of individual SARS-CoV-2 RNA molecules: a new paradigm for infection dynamics and variant differences

Lee, J. Y.; Wing, P. A.; Gala, D. S.; Noerenberg, M.; Jarvelin, A. I.; Titlow, J.; Zhuang, X.; Palmalux, N.; Iselin, L.; Thompson, M. K.; Parton, R. M.; Wainman, A.; Agranoff, D.; James, W.; Castello, A.; McKeating, J. A.; Davis, I.

10.1101/2021.06.29.450133 — microbiology — Posted on 2021-07-09

2900 Defining the Immune Responses for SARS-CoV-2-Human Macrophage Interactions

Mostafa, M.; Yeapuri, P.; Machhi, J.; Olson, K.; Shahjin, F.; Zhou, Y.; Jingjing, L.; Pandey, K.; Acharya, A.; Byrareddy, S.; Mosley, L.; Gendelman, H.

10.1101/2021.07.07.449660 — immunology — Posted on 2021-07-09

2901 Meta-strategy learning in physical problem-solving: the effect of embodied experience

Allen, K. R.; Smith, K.; Bird, L.-A.; Tenenbaum, J. B.; Makin, T.; Cowie, D.

10.1101/2021.07.08.451333 — neuroscience — Posted on 2021-07-09

2902 Sensory attenuation for external events is produced by a competition for attentional resources

Fritz, C.; Flick, M.; Zimmermann, E.

10.1101/2021.07.08.451581 — neuroscience — Posted on 2021-07-09

2903 Melanopic stimulation does not affect psychophysical threshold sensitivity for luminance flicker

Vincent, J.; Haggerty, E. B.; Brainard, D. H.; Aguirre, G. K.

10.1101/2021.07.08.451597 — neuroscience — Posted on 2021-07-09

2904 MuscleNET: Mapping Electromyography to kinematic and dynamic biomechanical variables by machine learning

Nasr, A.; Bell, S. M.; He, J.; Whittaker, R. l.; Dickerson, C. R.; Jiang, N.; McPhee, J.

10.1101/2021.07.07.451532 — systems biology — Posted on 2021-07-09

2905 Multiplexed identification of RAS paralog imbalance as a driver of lung cancer growth

Tang, R.; Shuldiner, E. G.; Kelly, M.; Murray, C. W.; Hebert, J. D.; Andrejka, L.; Tsai, M. K.; Cai, H.; Li, Y.-C.; Wahl, G.; Jackson, P. K.; Petrov, D.; Winslow, M. M.

10.1101/2021.07.08.451571 — cancer biology — Posted on 2021-07-09

2906 Reflective mirror-based line-scan adaptive optics OCT

Pandiyan, V. P.; Jiang, X.; Kuchenbecker, J. A.; Sabesan, R.

10.1101/2021.07.07.451545 — bioengineering — Posted on 2021-07-09

2907 Myths and mechanisms: RecBCD and Chi hotspots as determinants of self vs. non-self

Subramaniam, S.; Smith, G. R.

10.1101/2021.07.08.451572 — genetics — Posted on 2021-07-09

2908 Sea Surface Temperatures Drive Historical Demography of Deep-Sea Fishes

Weber, M. D.; Carter, J. E.; Eytan, R. I.

10.1101/2021.07.07.451542 — evolutionary biology — Posted on 2021-07-09

2909 Large-scale deregulation of gene expression by artificial light at night in tadpoles of common toads

Touzot, M.; Lefebure, T.; Lengagne, T.; Secondi, J.; Dumet, A.; Konecny-Dupré, L.; Veber, P.; Navratil, V.; Duchamp, C.; Mondy, N.

10.1101/2021.07.08.451570 — ecology — Posted on 2021-07-09

2910 Cellular toxicity of iHAP1 and DT-061 does not occur through PP2A-B56 targeting

Vit, G.; Duro, J.; Rajendraprasad, G.; Hertz, E. P.; Holland, L.; Weisser, M. B.; McEwan, B.; Lopez-Mendez, B.; Montoya, G.; Mailand, N.; Maeda, K.; Kettenbach, A.; Nilsson, J.

10.1101/2021.07.08.451586 — cell biology — Posted on 2021-07-09

2911 Inside Information: Systematic within-node connectivity changes observed across tasks or groups

Luo, W.; Constable, R. T.

10.1101/2021.07.07.451429 — neuroscience — Posted on 2021-07-09

2912 Pre-trial predictors of conflict response efficacy in human dorsolateral prefrontal cortex

Herman, A. B.; Smith, E.; Yates, M.; McKhann, G.; Botvinick, M.; Hayden, B.; Sheth, S.

10.1101/2021.07.07.451322 — neuroscience — Posted on 2021-07-09

2913 Motion/direction-sensitive thalamic neurons project extensively to the middle layers of primary visual cortex

Zhuang, J.; Wang, Y.; Ouellette, N. D.; Turschak, E.; Larsen, R.; Takasaki, K. T.; Daigle, T. L.; Tasic, B.; Waters, J.; Zeng, H.; Reid, R. C.

10.1101/2021.07.07.451534 — neuroscience — Posted on 2021-07-09

2914 Unsupervised characterization of dynamic functional connectivity reveals age-associated differences in temporal stability and connectivity states during rest and task

Sastry, N. C.; Roy, D.; Banerjee, A.

10.1101/2021.07.08.451590 — neuroscience — Posted on 2021-07-09

2915 Pharmacokinetic Effects of Combined Exposure to Nicotine and THC via E-Cigarettes in Pregnant Rats

Breit, K. R.; Rodriguez, C.; Hussain, S.; Thomas, K.; Zeigler, M.; Gerasimidis, I.; Thomas, J. D.

10.1101/2021.07.07.451537 — pharmacology and toxicology — Posted on 2021-07-09

2916 Local CpG density affects the trajectory of age-associated epigenetic changes

Higham, J.; Zhang, Q.; Walker, R. M.; Harris, S. E.; Howard, D. M.; Hawkins, E. L.; Sandu, A.-L.; Steele, J. D.; Waiter, G. D.; Murray, A. D.; Evans, K. L.; McIntosh, A. M.; Visscher, P. M.; Deary, I. J.; Cox, S. R.; Sproul, D.

10.1101/2021.07.08.451539 — genetics — Posted on 2021-07-09

2917 Membrane Hydrophobicity Determines the Activation Free Energy of Passive Lipid Transport

Rogers, J. R.; Espinoza Garcia, G.; Geissler, P. L.

10.1101/2021.03.17.435885 — biophysics — Posted on 2021-07-09

2918 Flavonols and dihydroflavonols inhibit the main protease activity of SARS-CoV-2 and the replication of human coronavirus 229E

Zhu, Y.; Scholle, F.; Kisthardt, S. C.; Xie, D.

10.1101/2021.07.01.450756 — biochemistry — Posted on 2021-07-09

2919 Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples

Polavarapu, V. K.; Xing, P.; Zhang, H.; Zhao, M.; Mathot, L.; Zhao, L.; Rosen, G.; Swartling, F.; Sjoblom, T.; Chen, X.

10.1101/2021.07.08.450856 — genomics — Posted on 2021-07-09

2920 Long-range single-molecule mapping of chromatin modification in eukaryotes

Weng, Z.; Ruan, F.; Chen, W.; Xie, Z.; Xie, Y.; Zhang, C.; Chen, Z.; Wang, J.; Sun, Y.; Fang, Y.; Guo, M.; Tong, Y.; Li, Y.; Tang, C.

10.1101/2021.07.08.451578 — genomics — Posted on 2021-07-09

2921 Comparison and evaluation of statistical error models for scRNA-seq

Choudhary, S.; Satija, R.

10.1101/2021.07.07.451498 — genomics — Posted on 2021-07-09

2922 Early adaptation in a microbial community is dominated by mutualism-enhancing mutations

Venkataram, S.; Kuo, H.-Y.; Hom, E. F. Y.; Kryazhimskiy, S.

10.1101/2021.07.07.451547 — evolutionary biology — Posted on 2021-07-09

2923 Reconstruction of nitrogenase predecessors suggests origin from maturase-like enzymes

Garcia, A. K.; Kolaczkowski, B.; Kacar, B.

10.1101/2021.07.07.451390 — evolutionary biology — Posted on 2021-07-09

2924 Legionella pneumophila targets autophagosomes and promotes host autophagy during late infection

Noll, R. R.; Pike, C. M.; Lehman, S. S.; Williamson, C.; Neunuebel, R.

10.1101/2021.07.08.451723 — microbiology — Posted on 2021-07-09

2925 Functional diversity increases the efficacy of phage combinations

Wright, R. C. T.; Friman, V.; Smith, M. C. M.; Brockhurst, M.

10.1101/2021.07.09.451746 — microbiology — Posted on 2021-07-09

2926 Genomic and functional characterization of Pseudomonas aeruginosa-targeting bacteriophages isolated from hospital wastewater

Nordstrom, H. R.; Evans, D. R.; Finney, A. G.; Westbrook, K. J.; Zamora, P. F.; Iovleva, A.; Yassin, M. H.; Bomberger, J. M.; Shields, R. K.; Doi, Y.; Van Tyne, D.

10.1101/2021.07.08.451722 — microbiology — Posted on 2021-07-09

2927 Global analysis of the specificities and targets of endoribonucleases from E. coli toxin-antitoxin systems

Culviner, P. H.; Nocedal, I.; Fortune, S.; Laub, M. T.

10.1101/2021.07.08.451724 — microbiology — Posted on 2021-07-09

2928 The neutralization potency of anti-SARS-CoV-2 therapeutic human monoclonal antibodies is retained against novel viral variants

Makdasi, E.; Zvi, A.; Alcalay, R.; Noy-Porat, T.; Peretz, E.; Mechaly, A.; Levy, Y.; Epstein, E.; Chitlaru, T.; Tennenhouse, A.; Aftalion, M.; Gur, D.; Paran, N.; Tamir, H.; Zimhony, O.; Weiss, S.; Mandelboim, M.; Mendelson, E.; Zuckerman, N.; Nemet, I.; Kliker, L.; Yitzhaki, S.; Shapira, S. C.; Israely, T.; Fleishman, S. J.; Mazor, O.; Rosenfeld, R.

10.1101/2021.04.01.438035 — immunology — Posted on 2021-07-09

2929 Neurotoxic astrocytic glypican-4 drives APOE4-dependent tau pathology

Ramamoorthy, S.; Gorbachev, K.; Pereira, A.

10.1101/2021.07.07.451493 — neuroscience — Posted on 2021-07-09

2930 Rate-Based Decoding of Images from Multi-Region, High Resolution, Electrode Recordings In the Mouse Visual System

Fritz, C. B.

10.1101/2021.07.07.451504 — neuroscience — Posted on 2021-07-09

2931 Forward Entrainment: Evidence, Controversies, Constraints, and Mechanisms

Saberi, K.; Hickok, G.

10.1101/2021.07.06.451373 — neuroscience — Posted on 2021-07-09

2932 metaboprep: an R package for pre-analysis data description and processing.

Hughes, D. A.; Taylor, K. A.; McBride, N.; Lee, M. A.; Mason, D.; Lawlor, D. A.; Timpson, N. J.; Corbin, L. J.

10.1101/2021.07.07.451488 — bioinformatics — Posted on 2021-07-09

2933 DnoisE: Distance denoising by Entropy. An open-source parallelizable alternative for denoising sequence datasets

Antich, A.; Palacin, C.; Turon, X.; Wangensteen, O. S.

10.1101/2021.07.07.451520 — bioinformatics — Posted on 2021-07-09

2934 Directional Cell Migration Guided by a Strain Gradient

Yang, F.; Sun, Y.

10.1101/2021.07.07.451494 — bioengineering — Posted on 2021-07-09

2935 Ecological inference using data from accelerometers needs careful protocols

Garde, B.; Wilson, R. P.; Fell, A.; Cole, N.; Tatayah, V.; Holton, M. D.; Rose, K. A. R.; Metcalfe, R. S.; Robotka, H.; Wikelski, M.; Tremblay, F.; Whelan, S.; Elliott, K. H.; Shepard, E.

10.1101/2021.07.07.451487 — animal behavior and cognition — Posted on 2021-07-09

2936 Genome Profiling of SARS-CoV-2 in Indonesia, ASEAN and the Neighbouring East Asian Countries: Features, Challenges and Achievements

Cahyani, I.; Putro, E. W.; Ridwanuloh, A. M.; Wibowo, S.; Hariyatun, H.; Syahputra, G.; Akbariani, G.; Utomo, A. R.; Ilyas, M.; Loose, M. W.; Kusharyoto, W.; Susanti, S.

10.1101/2021.07.06.451270 — genomics — Posted on 2021-07-09

2937 Phylodynamic inference for emerging viruses using segregating sites

Park, Y.; Martin, M. A.; Koelle, K.

10.1101/2021.07.07.451508 — evolutionary biology — Posted on 2021-07-09

2938 The preeminent role of directional selection in generating extreme morphological change in Glyptodonts (Cingulata; Xenarthra)

Machado, F. A.; Marroig, G.; Hubbe, A.

10.1101/2021.07.07.451530 — evolutionary biology — Posted on 2021-07-09

2939 Recruitment of Scc2/4 to double strand breaks depends on γH2A and DNA end resection

Scherzer, M.; Giordano, F.; Ferran, M. S.; Ström, L.

10.1101/2021.07.09.451733 — cell biology — Posted on 2021-07-09

2940 The characteristics of the HIV-1 Env glycoprotein contribute to viral pathogenesis

Perez-Yanes, S.; Pernas, M.; Marfil, S.; Cabrera-Rodriguez, R.; Ortiz, R.; Rovirosa, C.; Estevez-Herrera, J.; Olivares, I.; Casado, C.; Lopez-Galindez, C.; Blanco, J.; Valenzuela-Fernandez, A.

10.1101/2021.07.07.451566 — microbiology — Posted on 2021-07-09

2941 Rescuing epileptic and behavioral alterations in a Dravet syndrome mouse model by inhibiting eEF2K

Beretta, S.; Ponzoni, L.; Gritti, L.; Scalmani, P.; Mantegazza, M.; Sala, M.; Verpelli, C.; Sala, C.

10.1101/2021.07.07.451562 — neuroscience — Posted on 2021-07-09

2942 Inhibition of cholinergic interneurons potentiates corticostriatal transmission in D1 receptor-expressing medium-sized spiny neurons and restores motor learning in parkinsonian condition

Laverne, G.; Pesce, J.; Reynders, A.; Melon, C.; Kerkerian-Le Goff, L.; Maurice, N.; Beurrier, C.

10.1101/2021.07.07.451477 — neuroscience — Posted on 2021-07-09

2943 Dissociable Multi-scale Patterns of Development in Personalized Brain Networks

Pines, A. R.; Larsen, B.; Cui, Z.; Sydnor, V. J.; Bertolero, M. A.; Adebimpe, A.; Alexander-Bloch, A. F.; Davatzikos, C.; Fair, D. A.; Gur, R. C.; Gur, R. E.; Li, H.; Milham, M. P.; Moore, T. M.; Murtha, K.; Parkes, L.; Thompson-Schill, S. L.; Shanmugan, S.; Shinohara, R. T.; Weinstein, S. M.; Bassett, D. S.; Fan, Y.; Satterthwaite, T. D.

10.1101/2021.07.07.451458 — neuroscience — Posted on 2021-07-09

2944 First detection of herpesvirus and prevalence of mycoplasma infection in free-ranging Hermann s tortoises (Testudo hermanni), and in potential pet vectors

Ballouard, J.-m.; Bonnet, X.; Jourdan, J.; Martinez-Silvestre, A.; Gagno, S.; Fertard, B.; Caron, S.

10.1101/2021.01.22.427726 — zoology — Posted on 2021-07-09

2945 Extended Graphical Lasso for Multiple Interaction Networks for High Dimensional Omics Data

Xu, Y.; Jiang, H.; Jiang, W.

10.1101/2021.02.16.431400 — systems biology — Posted on 2021-07-09

2946 Plant inositol-phosphate-glycans and a fucosylated xyloglucan oligosaccharide are accumulated upon Arabidopsis thaliana/ Botrytis cinerea infection

Voxeur, A.; Sechet, J.; Vernhettes, S.

10.1101/2021.06.25.449971 — plant biology — Posted on 2021-07-09

2947 Is photosynthetic enhancement sustained through three years of elevated CO2 in a 175 year old oaks?

Gardner, A. M.; Ellsworth, D. S.; Crous, K. Y.; Pritchard, J.; Mackenzie, R. A.

10.1101/2020.12.16.416255 — plant biology — Posted on 2021-07-09

2948 The disease associated Tau35 fragment has an increased propensity to aggregate compared to full-length tau

Lyu, C.; Da Vela, S.; Al-Hilaly, Y. K.; Marshall, K.; Thorogate, R.; Svergun, D.; Serpell, L.; Pastore, A.; Hanger, D. P.

10.1101/2021.07.08.451675 — biophysics — Posted on 2021-07-09

2949 Identifying Protein Complexes in Protein-protein Interaction Data using Graph Convolution Network

Zaki, N.; Singh, H.

10.1101/2021.07.07.451457 — bioinformatics — Posted on 2021-07-09

2950 The Thousand Polish Genomes Project- a national database of Polish variant allele frequencies

Kaja, E.; Lejman, A.; Sielski, D.; Sypniewski, M.; Gambin, T. L.; Suchocki, T.; Dawidziuk, M.; Golik, P.; Wojtaszewska, M.; Stepien, M.; Szyda, J.; Lisiak-Teodorczyk, K.; Wolbach, F.; Kołdziejska, D.; Ferdyn, K.; Wozna, A.; Zytkiewicz, M.; Bodora-Troinska, A.; Elikowski, W.; Krol, Z.; Zaczynski, A.; Pawlak, A.; Gil, R.; Wierzba, W.; Dobosz, P.; Zawadzka, K.; Zawadzki, P.; Sztromwasser, P.

10.1101/2021.07.07.451425 — genomics — Posted on 2021-07-09

2951 Single Cell Transcriptomics Reveals Cell Type Specific Diversification in Human Heart Failure

Koenig, A. L.; Shchukina, I.; Andhey, P. S.; Zaitsev, K.; Lai, L.; Amrute, J.; Bajpai, G.; Bredemeyer, A.; Smith, G.; Jones, C.; Terrebonne, E.; Rentschler, S. L.; Artyomov, M. N.; Lavine, K. J.

10.1101/2021.07.06.451312 — genomics — Posted on 2021-07-09

2952 A geospatial mapping pipeline for ecologists

van den Hoogen, J.; Robmann, N.; Routh, D.; Lauber, T.; van Tiel, N.; Danylo, O.; Crowther, T. W.

10.1101/2021.07.07.451145 — ecology — Posted on 2021-07-09

2953 Skilful decadal-scale prediction of fish habitat and distribution shifts

Payne, M. R.; Miesner, A. K.; Keenlyside, N.; Yang, S.; Yeager, S. G.; Danabasoglu, G.; Matei, D.

10.1101/2021.07.07.451446 — ecology — Posted on 2021-07-09

2954 The potential for mobile demersal fishing to reduce carbon storage and sequestration in seabed sediments

Epstein, G.; Hawkins, J. P.; Norris, C. R.; Roberts, C. M.

10.1101/2021.07.07.450307 — ecology — Posted on 2021-07-09

2955 Linguistic modulation of the neural encoding of phonemes

Kim, S.-G.; De Martino, F.; Overath, T.

10.1101/2021.07.05.451175 — neuroscience — Posted on 2021-07-09

2956 The variability in potential biomarkers for cochlear synaptopathy after recreational noise exposure

Vande Maele, T.; Keshishzadeh, S.; De Poortere, N.; Dhooge, I.; Keppler, H.; Verhulst, S.

10.1101/2021.01.17.427007 — neuroscience — Posted on 2021-07-09

2957 The lateral entorhinal cortex is a hub for local and global dysfunction in pre-tauopathy states

Mandino, F.; Yeow, L. Y.; Bi, R.; Lee, S.; Bae, H. G.; Baek, S. H.; Lee, C. Y.; Mohammad, H.; Teoh, C. L.; Horien, C. L.; Lee, J.; Lai, M. K. P.; Jung, S.; Yu, F.; Olivo, M.; Gigg, J.; Grandjean, J.

10.1101/2020.04.03.022590 — neuroscience — Posted on 2021-07-09

2958 NHE6-Depletion Corrects ApoE4-Mediated Synaptic Impairments and Reduces Amyloid Plaque Load

Pohlkamp, T.; Xian, X.; Wong, C. H.; Durakoglugil, M. S.; Werthmann, G. C.; Saido, T. C.; Evers, B. M.; White, C. L.; Connor, J.; Hammer, R. E.; Herz, J.

10.1101/2021.03.22.436385 — neuroscience — Posted on 2021-07-09

2959 Learning differentially shapes prefrontal and hippocampal activity patterns during classical conditioning

Klee, J. L.; Souza, B. C.; Battaglia, F. P.

10.1101/2020.12.02.408468 — neuroscience — Posted on 2021-07-09

2960 EEG biomarkers of free recall

Katerman, B. S.; Li, Y.; Pazdera, J. K.; Keane, C.; Kahana, M. J.

10.1101/2021.04.30.442192 — neuroscience — Posted on 2021-07-09

2961 Intrinsic Network Connectivity Reflects the Cyclic Trajectory of Migraine Attacks

Stankewitz, A.; Schulz, E.

10.1101/2021.06.30.450593 — neuroscience — Posted on 2021-07-09

2962 Promises and pitfalls of Topological Data Analysis for brain connectivity analysis

Caputi, L.; Pidnebesna, A.; Hlinka, J.

10.1101/2021.02.10.430469 — neuroscience — Posted on 2021-07-09

2963 A predictive processing model of episodic memory and time perception

Fountas, Z.; Sylaidi, A.; Nikiforou, K.; Seth, A.; Shanahan, M.; Roseboom, W.

10.1101/2020.02.17.953133 — neuroscience — Posted on 2021-07-09

2964 Mechanical demands of the two-handed hardstyle kettlebell swing in novice older adults: an exploratory profile

Meigh, N. J.; Hing, W. A.; Schram, B.; Keogh, J. W. L.

10.1101/2021.05.17.444430 — physiology — Posted on 2021-07-09

2965 Atrazine induced In vivo immunotoxicity in Bivalves

Navalgund, M. Z. I. A. R.; Navalgund, M. A. I. A.

10.1101/2021.06.29.450311 — pharmacology and toxicology — Posted on 2021-07-09

2966 Sequence determines the switch in the fibril forming regions in the low complexity FUS protein and its variants

Kumar, A.; Chakraborty, D.; Mugnai, M. L.; Straub, J. E.; Thirumalai, D.

10.1101/2021.07.08.451535 — biophysics — Posted on 2021-07-09

2967 Emergent collective locomotion in an active polymer model of entangled worm blobs

Nguyen, C.; Ozkan-Aydin, Y.; Tuazon, H.; Goldman, D. I.; Bhamla, M. S.; Peleg, O.

10.1101/2021.07.08.451507 — biophysics — Posted on 2021-07-09

2968 Protein structural features predict responsiveness to pharmacological chaperone treatment for three lysosomal storage disorders

Woodard, J. C.; Zheng, W.; Zhang, Y.

10.1101/2021.07.08.451652 — biophysics — Posted on 2021-07-09

2969 Effects of Ionic Strength on Gating and Permeation of TREK-2 K2P channels

Conrad, L. J.; Proks, P.; Tucker, S. J.

10.1101/2021.07.08.451686 — biophysics — Posted on 2021-07-09

2970 Transcranial photoacoustic characterization of neurovascular physiology during early-stage photothrombotic stroke in neonatal piglets in vivo

Kang, J.; Liu, X.; Cao, S.; Zeiler, S. R.; Graham, E. M.; Boctor, E. M.; Koehler, R. C.

10.1101/2021.07.08.451613 — biophysics — Posted on 2021-07-09

2971 Stress relaxation amplitude of hydrogels determines migration, proliferation, and morphology of cells in 3-D

Hazur, J.; Endrizzi, N.; Schubert, D. W.; Boccaccini, A. R.; Fabry, B.

10.1101/2021.07.08.451608 — biophysics — Posted on 2021-07-09

2972 Structural modeling of the hERG potassium channel and associated drug interactions

Maly, J.; Emigh, A.; DeMarco, K.; Furutani, K.; Sack, J. T.; Clancy, C.; Vorobyov, I.; Yarov-Yarovoy, V.

10.1101/2021.07.08.451699 — biophysics — Posted on 2021-07-09

2973 Structure and Mechanism of Hedgehog Acyl Transferase

Coupland, C. E.; Andrei, S. A.; Ansell, T. B.; Carrique, L.; Kumar, P.; Sefer, L.; Schwab, R. A.; Byrne, E. F. X.; Pardon, E.; Steyaert, J.; Magee, A. I.; Sansom, M. S. P.; Tate, E. W.; Siebold, C.

10.1101/2021.07.08.451580 — biophysics — Posted on 2021-07-09

2974 Simulations of dynamically cross-linked actin networks: morphology, rheology, and hydrodynamic interactions

Maxian, O.; Pelaez, R. P.; Mogilner, A.; Donev, A.

10.1101/2021.07.07.451453 — biophysics — Posted on 2021-07-09

2975 Automated identification of maximal differential cell populations in flow cytometry data

Yue, A.; Chauve, C.; Libbrecht, M.; Brinkman, R.

10.1101/837765 — bioinformatics — Posted on 2021-07-09

2976 GRAFIMO: variant and haplotype aware motif scanning on pangenome graphs

Tognon, M.; Bonnici, V.; Garrison, E.; Giugno, R.; Pinello, L.

10.1101/2021.02.04.429752 — bioinformatics — Posted on 2021-07-09

2977 Inference of an integrative, executable network for Rheumatoid Arthritis combining data-driven machine learning approaches and a state-of-the-art mechanistic disease map

Miagoux, Q.; Singh, V.; de Mezquita, D.; Chaudru, V.; Elati, M.; Petit-Teixeira, E.; Niarakis, A.

10.1101/2021.01.28.428679 — bioinformatics — Posted on 2021-07-09

2978 MPA_Pathway_Tool: User-friendly, automatic assignment of microbial community data on metabolic pathways

Walke, D.; Schallert, K.; Ramesh, P.; Benndorf, D.; Lange, E.; Reichl, U.; Heyer, R.

10.1101/2021.07.07.450993 — bioinformatics — Posted on 2021-07-09

2979 Dug: A Semantic Search Engine Leveraging Peer-Reviewed Literature to Span Biomedical Data Repositories

Waldrop, A. M.; Cheadle, J. B.; Bradford, K.; Braswell, N. T.; Watson, M.; Crerar, A.; Ball, C.; Kebede, Y.; Schreep, C.; Linebaugh, P. J.; Hiles, H.; Boyles, R.; Bizon, C.; Krishnamurthy, A.; Cox, S.

10.1101/2021.07.07.451461 — bioinformatics — Posted on 2021-07-09

2980 Efficient gradient boosting for prognostic biomarker discovery

Li, K.; Yao, S.; Zhang, Z.; Cao, B.; Wilson, C.; Kuan, P.; Zhu, R.; Wang, X.

10.1101/2021.07.06.451263 — bioinformatics — Posted on 2021-07-09

2981 Novel drivers of virulence in Clostridioides difficile identified via context-specific metabolic network analysis

Jenior, M. L.; Leslie, J. L.; Powers, D. A.; Garrett, E. M.; Walker, K. A.; Dickenson, M. E.; Petri, W. A.; Tamayo, R.; Papin, J. A.

10.1101/2020.11.09.373480 — bioengineering — Posted on 2021-07-09

2982 The molecular appearance of native TRPM7 channel complexes identified by high-resolution proteomics

Kollewe, A.; Chubanov, V.; Tseung, F. T.; Haupt, A.; Müller, C. S.; Bildl, W.; Schulte, S.; Nicke, A.; Fakler, B.; Gudermann, T.

10.1101/2021.07.09.451738 — biochemistry — Posted on 2021-07-09

2983 Structure of mycobacterial CIII2CIV2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203)

Yanofsky, D. J.; Di Trani, J. M.; Krol, S.; Abdelaziz, R.; Bueler, S. A.; Imming, P.; Brzezinski, P.; Rubinstein, J. L.

10.1101/2021.07.06.451285 — biochemistry — Posted on 2021-07-09

2984 Machine learning algorithms can predict tail biting outbreaks in pigs using feeding behaviour records

Ollagnier, C.; Kasper, C.; Wallenbeck, A.; Keeling, L.; Bigdeli, S. A.

10.1101/2021.05.11.443554 — animal behavior and cognition — Posted on 2021-07-09

2985 Epigenetic Regulation of Nuclear Lamina-Associated Heterochromatin by HAT1 and the Acetylation of Newly Synthesized Histones

Popova, L. V.; Nagarajan, P.; Lovejoy, C. M.; Sunkel, B. D.; Gardner, M. L.; Wang, M.; Freitas, M. A.; Stanton, B.; Parthun, M. R.

10.1101/2021.06.28.450212 — genomics — Posted on 2021-07-09

2986 Expansion of mutation-driven haematopoietic clones is associated with insulin resistance and low HDL-cholesterol in individuals with obesity

van Deuren, R. C.; Andersson-Assarsson, J. C.; Kristensson, F. M.; Steehouwer, M.; Sjöholm, K.; Svensson, P.-A.; Pieterse, M.; Gilissen, C.; Taube, M.; Jacobson, P.; Perkins, R.; Brunner, H. G.; Netea, M. G.; Peltonen, M.; Carlsson, B.; Hoischen, A.; Carlsson, L. M.

10.1101/2021.05.12.443095 — genomics — Posted on 2021-07-09

2987 Multiplex genotyping method to validate the multiallelic genome editing outcomes using machine learning-assisted long-read sequencing

Kuno, A.; Ikeda, Y.; Ayabe, S.; Kato, K.; Sakamoto, K.; Suzuki, S.; Morimoto, K.; Wakimoto, A.; Mikami, N.; Ishida, M.; Iki, N.; Hamada, Y.; Takemura, M.; Daitoku, Y.; Tanimoto, Y.; Dinh, T. T.; Murata, K.; Hamada, M.; Muratani, M.; Yoshiki, A.; Sugiyama, F.; Takahashi, S.; Mizuno, S.

10.1101/2020.12.14.422641 — genomics — Posted on 2021-07-09

2988 A mutational gradient drives somatic mutation accumulation in mitochondrial DNA and influences germline polymorphisms and genome composition

Sanchez-Contreras, M.; Sweetwyne, M. T.; Kohrn, B. F.; Tsantilas, K. A.; Fredrickson, J.; Whitson, J. A.; Campbell, M. D.; Rabinovitch, P. S.; Marcinek, D. J.; Kennedy, S. R.

10.1101/2021.06.18.448725 — genomics — Posted on 2021-07-09

2989 Causes of variability in estimates of mutational variance from mutation accumulation experiments

Conradsen, C.; Blows, M. W.; McGuigan, K.

10.1101/2021.07.07.451460 — genetics — Posted on 2021-07-09

2990 Gene co-expression reveals the modularity and integration of C4 and CAM in Portulaca

Gilman, I. S.; Moreno-Villena, J. J.; Lewis, Z. R.; Goolsby, E. W.; Edwards, E. J.

10.1101/2021.07.07.451465 — evolutionary biology — Posted on 2021-07-09

2991 Soil conditions drive belowground trait space in temperate agricultural grasslands

Lachaise, T. P.-A.; Bergmann, J.; Hoelzel, N.; Klaus, V.; Kleinebecker, T.; Rillig, M. C.; van Kleunen, M.

10.1101/2021.07.07.450881 — ecology — Posted on 2021-07-09

2992 A framework for assessing the skill and value of operational recruitment forecasts

Kiaer, C.; Neuenfeldt, S.; Payne, M. R.

10.1101/2021.07.05.451182 — ecology — Posted on 2021-07-09

2993 From heterogenous morphogenetic fields to homogeneous regions as a step towards understanding complex tissue dynamics

Yamashita, S.; Guirao, B.; Graner, F.

10.1101/696252 — developmental biology — Posted on 2021-07-09

2994 Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins

Nowicka, U.; Chroscicki, P.; Stroobants, K.; Sladowska, M.; Turek, M.; Uszczynska-Ratajczak, B.; Kundra, R.; Goral, T.; Perni, M.; Dobson, C. M.; Vendruscolo, M.; Chacinska, A.

10.1101/2021.05.02.442342 — molecular biology — Posted on 2021-07-09

2995 The 16S microbiota of Budu, the Malaysian fermented anchovy sauce

Md Zoqratt, M. Z. H.; Gan, H. M.

10.1101/2020.03.10.986513 — molecular biology — Posted on 2021-07-09

2996 Interplay between disordered regions in RNAs and proteins modulates interactions within stress granules and processing bodies

Vandelli, A.; Samper, F. C.; Torrent Burgas, M.; Sanchez de Groot, N.; Tartaglia, G. G.

10.1101/2021.05.05.442738 — molecular biology — Posted on 2021-07-09

2997 Post-transcriptional regulation of Leishmania fitness gain

Piel, L.; Rajan, K. S.; Bussotti, G.; Varet, H.; Legendre, R.; Proux, C.; Douche, T.; Giai Gianetto, Q.; Chaze, T.; Vojtkova, B.; Gordon-Bar, N.; Doniger, T.; Cohen-Chalamish, S.; Rengaraj, P.; Besse, C.; Boland, A.; Sadlova, J.; Deleuze, J.-F.; Matondo, M.; Unger, R.; Volf, P.; Michaeli, S.; Pescher, P.; Spaeth, G. F.

10.1101/2021.03.22.436378 — microbiology — Posted on 2021-07-09

2998 Micronutrient supplements with iron promote disruptive protozoan and fungal communities in the developing infant gut

Popovic, A.; Bourdon, C.; Wang, P. W.; Guttman, D. S.; Soofi, S.; Bhutta, Z. A.; Bandsma, R. H. J.; Parkinson, J.; Pell, L. G.

10.1101/2021.07.06.451346 — microbiology — Posted on 2021-07-09

2999 Top-down contextual requirement to suppress self-movement influences grasp-specific modulation of corticospinal excitability during action observation

Jerjian, S. J.; Davare, M.; Kraskov, A.

10.1101/2020.06.25.171629 — neuroscience — Posted on 2021-07-09

3000 Noradrenergic control of non-REM sleep substates

Osorio-Forero, A.; Cardis, R.; Vantomme, G.; Guillaume-Gentil, A.; Katsioudi, G.; Fernandez, L. M.; Luthi, A.

10.1101/2021.03.08.434399 — neuroscience — Posted on 2021-07-09

3001 Laminar Mechanisms of Saccadic Suppression in Primate Visual Cortex

Denagamage, S.; Morton, M.; Reynolds, J.; Jadi, M.; Nandy, A.

10.1101/2021.01.09.426063 — neuroscience — Posted on 2021-07-09

3002 Transcranial magnetic stimulation entrains alpha oscillatory activity in occipital cortex

Lin, Y.-J.; Shukla, L.; Dugue, L.; Valero-Cabre, A.; Carrasco, M.

10.1101/2021.01.09.426064 — neuroscience — Posted on 2021-07-09

3003 Stimulus-induced narrowband gamma oscillations are test-retest reliable in healthy elderly in human EEG

Kumar, W. S.; Manikandan, K.; Murty, D. V. P. S.; Ramesh, R. G.; Purokayastha, S.; Javali, M.; Rao, N. P.; Ray, S.

10.1101/2021.07.06.451226 — neuroscience — Posted on 2021-07-09

3004 Distinct corticostriatal compartments drive competition between adaptive and automatized behavior

Barnett, W. H.; Kuznetsov, A.; Lapish, C. C.

10.1101/2021.05.21.445068 — neuroscience — Posted on 2021-07-09

3005 Experiencing surprise: the temporal dynamics of its impact on memory

Frank, D.; Kafkas, A.; Montaldi, D.

10.1101/2020.12.15.422817 — neuroscience — Posted on 2021-07-09

3006 A tractable bottom-up model of the yeast polarity genotype-phenotype map for evolutionary relevant predictions

Daalman, W. K.-G.; Sweep, E.; Laan, L.

10.1101/2020.11.09.374363 — systems biology — Posted on 2021-07-09

3007 Hydrogen peroxide modulates lignin and silica deposits in sorghum roots

Zexer, N.; Elbaum, R.

10.1101/2021.02.01.429181 — plant biology — Posted on 2021-07-09

3008 The evolution of two distinct strategies of moth flight

Aiello, B. R.; Sikandar, U. B.; Minoguchi, H.; Bhinderwala, B.; Hamilton, C. A.; Kawahara, A. Y.; Sponberg, S.

10.1101/2020.10.27.358176 — physiology — Posted on 2021-07-09

3009 Molecular Response to PARP1 Inhibition in Ovarian Cancer Cells as Determined by Mass Spectrometry Based Proteomics

Franz, A.; Coscia, F.; Shen, C.; Charaoui, L.; Mann, M.; Sander, C.

10.1101/2021.03.12.435005 — cancer biology — Posted on 2021-07-09

3010 Somatic hypomethylation of pericentromeric SST1 repeats and tetraploidization in human colorectal cancer cells

Gonzalez, B.; Navarro-Jimenez, M.; Alonso-De Gennaro, M. J.; Jansen, S. M.; Granada, I.; Perucho, M.; Alonso, S.

10.1101/2021.02.19.431645 — cancer biology — Posted on 2021-07-09

3011 FANCD2 directly inhibits DNA2 nuclease at stalled replication forks and acts as a RAD51 mediator in strand exchange

Liu, W.; Roubal, I.; Polaczek, P.; Meng, Y.; Choe, W.-c.; Caron, M. C.; Sedgeman, C. A.; Xi, Y.; Liu, C.; Wu, Q.; Zheng, L.; Masson, J. Y.; Shen, B.; Campbell, J. L.

10.1101/2021.07.08.450798 — biochemistry — Posted on 2021-07-09

3012 Humans can navigate complex graph structures acquired during latent learning

Rmus, M.; Ritz, H.; Hunter, L. E.; Bornstein, A. M.; Shenhav, A.

10.1101/723072 — animal behavior and cognition — Posted on 2021-07-09

3013 The geometry of domain-general performance monitoring representations in the human medial frontal cortex

Fu, Z.; Beam, D.; Chung, J. M.; Reed, C. M.; Mamelak, A. N.; Adolphs, R.; Rutishauser, U.

10.1101/2021.07.08.451594 — neuroscience — Posted on 2021-07-08

3014 Allele-specific expression links diverse cis-regulatory mutations to recurrent gene dysregulation in high-risk neuroblastoma

Sen, A.; Huo, Y.; Elster, J.; Zage, P. E.; McVicker, G. P.

10.1101/2021.07.08.451695 — cancer biology — Posted on 2021-07-08

3015 Positive selection and enhancer evolution shaped lifespan and body mass in great apes

Tejada-Martinez, D.; Avelar, R. A.; de Magalhaes, J. P.; Lopes, I.; Zhang, B.; Novoa, G.; Trizzino, M.

10.1101/2021.07.08.451631 — genomics — Posted on 2021-07-08

3016 Mosaic cis-regulatory evolution drives transcriptional partitioning of HERVH endogenous retrovirus in the human embryo

Carter, T. A.; Singh, M.; Dumbovic, G.; Chobirko, J.; Rinn, J.; Feschotte, C.

10.1101/2021.07.08.451617 — evolutionary biology — Posted on 2021-07-08

3017 CLUH interactome reveals an association to SPAG5 and a proximity to the translation of mitochondrial protein

Hemono, M.; Haller, A.; Chicher, J.; Duchene, A.-M.; Ngondo, R. P.

10.1101/2021.07.08.451585 — molecular biology — Posted on 2021-07-08

3018 The role of posterior ventral stream areas for viewpoint-invariant object recognition

Nestmann, S.; Karnath, H.-O.; Rennig, J.

10.1101/2021.07.07.451407 — neuroscience — Posted on 2021-07-08

3019 Pseudomonas syringae effector AvrE associates with plant membrane nanodomains and binds phosphatidylinositides in vitro

Xin, X.; Kinch, L.; Cai, B.; Paasch, B. C.; Kvitko, B.; Grishin, N. V.; He, S. Y.

10.1101/2021.07.08.451616 — pathology — Posted on 2021-07-08

3020 The multilayered organization of water-soluble proteins

Wang, L.

10.1101/2021.07.07.451496 — biophysics — Posted on 2021-07-08

3021 Protein kinase signalling at the Leishmania kinetochore captured by XL-BioID

Geoghegan, V.; Jones, N. G.; Dowle, A.; Mottram, J. C.

10.1101/2021.07.08.451598 — biochemistry — Posted on 2021-07-08

3022 Fully resolved assembly of Cryptosporidium parvum

Menon, V. K.; Okhuysen, P. C.; Chappell, C.; Mahmoud, M.; Meng, Q.; Vee, V.; Doddapaneni, H.; Han, Y.; Salvi, S.; Bhamidipati, S.; Kottapalli, K.; Weissenberger, G.; Shen, H.; Ross, M. C.; Hoffman, K. L.; Cregeen, S. J.; Muzny, D. M.; Metcalf, G. A.; Gibbs, R. A.; Petrosino, J. F.; Sedlazeck, F. J.

10.1101/2021.07.07.451495 — genomics — Posted on 2021-07-08

3023 Growth temperature is the principal driver of chromatinization in archaea

Hocher, A.; Borrel, G.; Fadhlaoui, K.; Brugere, J.-F.; Gribaldo, S.; Warnecke, T.

10.1101/2021.07.08.451601 — evolutionary biology — Posted on 2021-07-08

3024 Concurrent evolution of anti-aging gene duplications and cellular phenotypes in long-lived turtles

Glaberman, S.; Bulls, S. E.; Vazquez, J. M.; Chiari, Y.; Lynch, V. J.

10.1101/2021.07.07.451454 — evolutionary biology — Posted on 2021-07-08

3025 SPE-51, a sperm secreted protein with an Immunoglobulin-like domain, is required for sperm-egg fusion in C. elegans

Mei, X.; Druzhinina, M.; Dharia, S.; Krauchunas, A. R.; Ni, J.; Singaravelu, G.; Gu, S. G.; Shakes, D. C.; Grant, B. D.; Singson, A. W.

10.1101/2021.07.07.451548 — developmental biology — Posted on 2021-07-08

3026 Establishment of 3D chromatin structure after fertilization and the metabolic switch at the morula-to-blastocyst transition require CTCF

Andreu, M. J.; Alvarez-Franco, A.; Portela, M.; Gimenez-Llorente, D.; Cuadrado, A.; Badia-Careaga, C.; Tiana, M.; Losada, A.; Manzanares, M.

10.1101/2021.07.07.451492 — developmental biology — Posted on 2021-07-08

3027 The EGF-motif containing protein SPE-36 is a secreted protein required for sperm function at fertilization in C. elegans

Krauchunas, A. R.; Marcello, M. R.; Looper, A.; Mei, X.; Putiri, E.; Singaravelu, G.; Ahmed, I. I.; Singson, A.

10.1101/2021.07.07.451551 — developmental biology — Posted on 2021-07-08

3028 A single cell transcriptome atlas reveals the heterogeneity of the healthy human cornea and identifies novel markers of the corneal limbus and stroma

Catala, P.; Groen, N.; Dehnen, J. A.; Soares, E.; van Velthoven, A. J.; Nuijts, R. M.; Dickman, M. M.; LaPointe, V. L.

10.1101/2021.07.07.451489 — cell biology — Posted on 2021-07-08

3029 Ultrastructural analysis of nasopharyngeal epithelial cells from patients with SARS-CoV-2 infection

Saraiva, K. L.; Vasconcelos, L. R.; Bezerra, M. F.; Arcoverde, R. M.; Brandao-Filho, S. P.; Ayres, C. F.; Figueiredo, R. C.; Pereira-Neves, A.

10.1101/2021.07.08.451607 — cell biology — Posted on 2021-07-08

3030 Cytoplasmic Switch of ARS2 Isoforms Promotes Nonsense-Mediated mRNA Decay and Arsenic Sensitivity

Mesa-Perez, M.; Hamilton, P.; Miranda-Rodriguez, A.; Brodie, N.; O'Sullivan, C.; Christie, J.; Ryan, B.; Chow, R.; Goodlett, D.; Nelson, C. J.; Howard, P.

10.1101/2021.07.08.451683 — molecular biology — Posted on 2021-07-08

3031 Combinations of Peptides Synergistically Activate the Regenerative Capacity of Skin Cells In Vitro

Flagler, M. J.; Tamura, M.; Laughlin, T.; Hartman, S.; Ashe, J.; Adams, R.; Kozak, K.; Cresswell, K.; Mullins, L.; Jarrold, B. B.; Isfort, R. J.; Sherrill, J. D.

10.1101/2021.07.07.451479 — molecular biology — Posted on 2021-07-08

3032 Multifactorial role of mitochondria in echinocandin tolerance revealed by transcriptome analysis of drug-tolerant cells

Garcia-Rubio, R.; Jimenez-Ortigosa, C.; DeGregorio, L.; Quinteros, C.; Shor, E.; Perlin, D. S.

10.1101/2021.07.07.451565 — microbiology — Posted on 2021-07-08

3033 Founder cell configuration drives competitive outcome within colony biofilms

Eigentler, L.; Kalamara, M.; Ball, G.; MacPhee, C. E.; Stanley-Wall, N. R.; Davidson, F. A.

10.1101/2021.07.08.451560 — microbiology — Posted on 2021-07-08

3034 EpicPCR-Directed Cultivation of a Candidatus Saccharibacteria Symbiont Reveals a Type IV Pili-dependent Epibiotic Lifestyle

Xie, B.; Wang, J.; Nie, Y.; Chen, D.; Hu, B.; Wu, X.; Du, W.

10.1101/2021.07.08.451036 — microbiology — Posted on 2021-07-08

3035 Pyroptosis-dependent and -independent cross-priming of CD8+ T cells by intestinal epithelial cell-derived antigen

Deets, K. A.; Nichols, R. D.; Rauch, I.; Vance, R. E.

10.1101/2021.07.08.451636 — immunology — Posted on 2021-07-08

3036 Holistic Characterization of Tumor Monocyte-to-Macrophage Differentiation Integrates Distinct Immune Phenotypes in Kidney Cancer

Mujal, A. M.; Combes, A. J.; Rao, A. A.; Binnewies, M.; Samad, B.; Tsui, J.; Boissonnas, A.; Pollack, J. L.; Arguello, R. J.; Ruhland, M. K.; Barry, K. C.; Chan, V.; Krummel, M. F.

10.1101/2021.07.07.451502 — immunology — Posted on 2021-07-08

3037 A realistic locomotory model of Drosophila larva for behavioral simulations.

Sakagiannis, P. P.; Jürgensen, A.-M.; Nawrot, M. P.

10.1101/2021.07.07.451470 — neuroscience — Posted on 2021-07-08

3038 Subspace alignment as a mechanism for binding

Fine, J. M.; Yoo, S. B. M.; Ebitz, B.; Hayden, B.

10.1101/2021.07.07.451472 — neuroscience — Posted on 2021-07-08

3039 Age-associated changes to neuronal dynamics involve a loss of inhibitory signaling in C. elegans

Wirak, G. S.; Florman, J.; Alkema, M. J.; Connor, C. W.; Gabel, C. V.

10.1101/2021.07.07.451497 — neuroscience — Posted on 2021-07-08

3040 Nicotine dependence and functional connectivity of insular cortex subregions

Ghahremani, D. G.; Pochon, J.-B.; Perez Diaz, M.; Tyndale, R. F.; Dean, A. C.; London, E. D.

10.1101/2021.07.07.451360 — neuroscience — Posted on 2021-07-08

3041 A natural marmoset model of genetic generalized epilepsy.

Yang, X.; Chen, Z.; Wang, Z.; He, G.; Li, Z.; Shi, Y.; Gong, N.; Zhao, B.; Takahashi, E.; Li, W.

10.1101/2021.07.07.451379 — neuroscience — Posted on 2021-07-08

3042 Intracellular phase separation of globular proteins facilitated by short cationic peptides

Yeong, V.; Wang, J.-w.; Horn, J. M.; Obermeyer, A. C.

10.1101/2021.07.08.450573 — synthetic biology — Posted on 2021-07-08

3043 Synthetic metabolic pathways for conversion of CO2 into secreted short- to medium-chain hydrocarbons using cyanobacteria

Yunus, I. S.; Anfelt, J.; Hudson, E. P.; Jones, P. R.

10.1101/2021.07.08.451587 — synthetic biology — Posted on 2021-07-08

3044 Evaluation of intranasal nafamostat or camostat for SARS-CoV-2 chemoprophylaxis in Syrian golden hamsters

Neary, M.; Box, H.; Sharp, J.; Tatham, L.; Curley, P.; Herriott, J.; Kijak, E.; Arshad, U.; Hobson, J. J.; Rajoli, R. K.; Pertinez, H.; Valentijn, A.; Dhaliwal, K.; McCaughan, F.; Rannard, S. P.; Kipar, A.; Stewart, J. P.; Owen, A.

10.1101/2021.07.08.451654 — pharmacology and toxicology — Posted on 2021-07-08

3045 Anti-tumor efficacy of an MMAE conjugated antibody targeting cell surface TACE/ADAM17-cleaved Amphiregulin in breast cancer

Lofgren, K. A.; Sreekumar, S.; Jenkins, E. C.; Ernzen, K. J.; Kenny, P. A.

10.1101/2021.07.07.451518 — cancer biology — Posted on 2021-07-08

3046 Differential effects of high versus low linear energy transfer (LET) radiation on type-I interferon (IFNβ) and TREX1 responses

Miles, D.; Cao, N.; Sandison, G.; Stewart, R. D.; Moffitt, G.; Pulliam, T. H.; Parvathaneni, U.; Goff, P.; Nghiem, P.; Stantz, K.

10.1101/2021.07.07.451516 — cancer biology — Posted on 2021-07-08

3047 Atomistic Simulations and Deep Mutational Scanning of Protein Stability and Binding Interactions in the SARS-CoV-2 Spike Protein Complexes with Nanobodies: Molecular Determinants of Mutational Escape Mechanisms

Verkhivker, G.; Agajanian, S.; Oztas, D. Y.; Gupta, G.

10.1101/2021.07.07.451538 — biophysics — Posted on 2021-07-08

3048 Peptides derived from gp43, the most antigenic protein from Paracoccidioides brasiliensis, form amyloid fibrils in vitro: implications for vaccine development

Cardim-Pires, T. R.; Ricardo, S.; Foguel, D.

10.1101/2021.07.08.451661 — biochemistry — Posted on 2021-07-08

3049 MLKL D144K mutation activates the necroptotic activity of the N-terminal MLKL domain

Hrovat-Schaale, K.; Kalic-Prolinsek, M.; Hadzi, S.; Lah, J.; Guncar, G.

10.1101/2021.07.08.451689 — biochemistry — Posted on 2021-07-08

3050 Kinetic characterization and thermostability of C. elegans cytoplasmic and mitochondrial malate dehydrogenases

Thomas, M. J.; Cassidy, E. R.; Robinson, D. S.; Walstrom, K. M.

10.1101/2021.07.08.451529 — biochemistry — Posted on 2021-07-08

3051 Citizen-science surveillance of triazole-resistant Aspergillus fumigatus in UK residential garden soils

Shelton, J. M.; Collins, R.; Uzzell, C. B.; Alghamdi, A.; Dyer, P. S.; Singer, A. C.; Fisher, M. C.

10.1101/2021.07.08.451577 — microbiology — Posted on 2021-07-08

3052 Phylogenomics Suggests the Origin of Obligately Anaerobic Anammox Bacteria Correlates with the Great Oxidation Event

Liao, T.; Wang, S.; Luo, H.

10.1101/2021.07.07.451387 — microbiology — Posted on 2021-07-08

3053 Antibody and T cell memory immune response after two doses of the BNT162b2 mRNA vaccine in older adults with and without prior SARS-CoV-2 infection

Demaret, J.; Corroyer-Simovic, B.; Alidjinou, E. K.; Goffard, A.; Trauet, J.; Miczek, S.; Vuotto, F.; Dendooven, A.; Huvent-Grelle, D.; Podvin, J.; Dreuil, D.; Faure, K.; Deplanque, D.; Bocket, L.; Duhamel, A.; Labreuche, J.; Sobaszek, A.; Puisieux, F.; Labalette, M.; Lefevre, G.

10.1101/2021.07.08.451426 — immunology — Posted on 2021-07-08

3054 In Silico Defined SARS-CoV2 Epitopes May Not Predict Immunogenicity to COVID19

Pan, K.; Chiu, Y.; Chen, M.; Wang, J.; Lai, I.; Singh, S.; Shaw, R. M.; Yee, C.

10.1101/2021.07.08.451555 — immunology — Posted on 2021-07-08

3055 Structure of a germline-like human antibody defines a neutralizing epitope on the SARS-CoV-2 spike NTD

Altomare, C. G.; Adelsberg, D. C.; Carreno, J. M.; Sapse, I. A.; Amanat, F.; Ellebedy, A.; Simon, V.; Krammer, F.; Bajic, G.

10.1101/2021.07.08.451649 — immunology — Posted on 2021-07-08

3056 Insights into the mutation T1117I in the spike and the lineage B.1.1.389 of SARS-CoV-2 circulating in Costa Rica

Molina-Mora, J. A.

10.1101/2021.07.08.451640 — bioinformatics — Posted on 2021-07-08

3057 LptB2FG is an ABC transporter with Adenylate Kinase activity regulated by LptC/A recruitment

Baeta, T.; Giandoreggio-Barranco, K.; Ayala, I.; Moura, E. C.; Sperandeo, P.; Polissi, A.; Simorre, J.-P.; Laguri, C.

10.1101/2021.07.08.451440 — biochemistry — Posted on 2021-07-08

3058 PlotXpress, a webtool for normalization and visualization of reporter expression data

Brandorff, E.; Galland, M.; Goedhart, J.

10.1101/2021.07.08.451595 — molecular biology — Posted on 2021-07-08

3059 Structure of the integrin receptor M2 headpiece in complex with a function-modulating nanobody

Jensen, R. K.; Pedersen, H.; Lorentzen, J.; Laursen, N. S.; Vorup-Jensen, T.; Andersen, G. R.

10.1101/2021.07.07.451531 — immunology — Posted on 2021-07-08

3060 Gating mechanism of human N-type voltage-gated calcium channel

Dong, Y.; Gao, Y.; Xu, S.; Wang, Y.; Yu, Z.; Li, Y.; Li, B.; Yang, B.; Zhang, X. C.; Jiang, D.; Huang, Z.; Zhao, Y.

10.1101/2021.07.08.451561 — neuroscience — Posted on 2021-07-08

3061 A DEEP LEARNING APPROACH TO ESTIMATING INITIAL CONDITIONS OF BRAIN NETWORK MODELS IN REFERENCE TO MEASURED FMRI DATA

Kashyap, A.; Plis, S.; Schirner, M.; Ritter, P.; Keilholz, S.

10.1101/2021.07.07.451431 — neuroscience — Posted on 2021-07-08

3062 Shallow neural networks trained to detect collisions recover features of visual loom-selective neurons

Zhou, B.; Li, Z.; Kim, S. S. Y.; Lafferty, J.; Clark, D. A.

10.1101/2021.07.07.451307 — neuroscience — Posted on 2021-07-08

3063 Patch-seq of mouse DRG neurons reveals candidate genes for specific mechanosensory functions

Parpaite, T.; Brosse, L.; Sejourne, N.; Laur, A.; Mechioukhi, Y.; Delmas, P.; Coste, B.

10.1101/2021.07.07.451447 — neuroscience — Posted on 2021-07-08

3064 Nonstoichiometric balanced complexes: Implications on the effective deficiency of the underlying metabolic network

Langary, D.; Kueken, A.; Nikoloski, Z.

10.1101/2021.07.07.451418 — systems biology — Posted on 2021-07-08

3065 All driven by energy demand? Integrative comparison of metabolism of Enterococcus faecalis wildtype and a glutamine synthase mutant

Loghmani, S. B.; Zitzow, E.; Koh, G. C.-C.; Ulmer, A.; Veith, N.; Großeholz, R.; Rossnagel, M.; Loesch, M.; Aebersold, R.; Kreikemeyer, B.; Fiedler, T.; Kummer, U.

10.1101/2021.07.07.451427 — systems biology — Posted on 2021-07-08

3066 Genome binning of viral entities from bulk metagenomics data

Johansen, J.; Plichta, D. R.; Nissen, J. N.; Jespersen, M. L.; Shah, S. A.; Deng, L.; Stokholm, J.; Bisgaard, H.; Nielsen, D. S.; Sorensen, S. J.; Rasmussen, S.

10.1101/2021.07.07.451412 — genomics — Posted on 2021-07-08

3067 H3K9me2 genome-wide distribution in the holocentric insect Spodoptera frugiperda (Lepidoptera: Noctuidae)

NHIM, S.; GIMENEZ, S.; NAIT SAIDI, R.; Severac, D.; Nam, K.; d'Alencon, E.; NEGRE, N.

10.1101/2021.07.07.451438 — genomics — Posted on 2021-07-08

3068 Calpains are required for efficient microtubule detyrosination

Bär, J.; Popp, Y.; Koudelka, T.; Tholey, A.; Mikhaylova, M.

10.1101/2021.07.08.451629 — cell biology — Posted on 2021-07-08

3069 Autoimmunity increases susceptibility to and mortality from sepsis

Jensen, I. J.; Jensen, S. N.; McGonagill, P. W.; Griffith, T. S.; Mangalam, A. K.; Badovinac, V. P.

10.1101/2021.07.06.451335 — immunology — Posted on 2021-07-08

3070 Crossmodal metaperception: Visual and tactile confidence share a common scale

Klever, L.; Mosebach, M.; Fiehler, K.; Mamassian, P.; Billino, J.

10.1101/2021.07.07.451428 — neuroscience — Posted on 2021-07-08

3071 Linking individual differences in cognitive control and perception: Meta-perception in older and younger adults

Klever, L.; Mamassian, P.; Billino, J.

10.1101/2021.07.07.451419 — neuroscience — Posted on 2021-07-08

3072 Structural-functional connectivity mapping of the insular cortex system: A combined data-driven and meta-analytic topic mapping approach

Klugah-Brown, B.; Wang, P.; Jiang, Y.; Becker, B.; Hu, P.; Biswal, B. B.

10.1101/2021.07.07.451405 — neuroscience — Posted on 2021-07-08

3073 Hippocampal Astrocytes Encode Reward Location

Doron, A.; Rubin, A.; Benmelech-Chovav, A.; Benaim, N.; Carmi, T.; Kreisel, T.; Ziv, Y.; Goshen, I.

10.1101/2021.07.07.451434 — neuroscience — Posted on 2021-07-08

3074 Virtual meetings promise to eliminate the geographical and administrative barriers and increase accessibility, diversity, and inclusivity

Wu, J.; Rajesh, A.; Huang, Y.-N.; Chhugani, K.; Acharya, R.; Peng, K.; Johnson, R. D.; Fiscutean, A.; Robles-Espinoza, C. D.; De La Vega, F. M.; Bao, R.; Mangul, S.

10.1101/2021.07.07.451408 — scientific communication and education — Posted on 2021-07-08

3075 Dual inhibition of anti-apoptotic proteins BCL-XL and MCL-1 enhances cytotoxicity of Nasopharyngeal carcinoma cells.

Abdul Rahman, S. F.; Azlan, A.; Lo, K.-W.; Azzam, G.; Mohana Kumaran, N.

10.1101/2021.07.07.451410 — cancer biology — Posted on 2021-07-08

3076 The smooth transition from many-legged to bipedal locomotion: Gradual ground force reduction and its impact on total ground reaction forces, body dynamics and gait transitions

Weihmann, T.

10.1101/2021.07.07.451417 — biophysics — Posted on 2021-07-08

3077 Feeding habits and the influence of pellet diameter on the feeding responses of the flathead grey mullet (Mugil cephalus) in captivity

Ramos-Judez, S.; Duncan, N. J.

10.1101/2021.07.07.451406 — animal behavior and cognition — Posted on 2021-07-08

3078 Topology and habitat assortativity drive neutral and adaptive diversification in spatial graphs

Boussange, V.; Pellissier, L.

10.1101/2021.07.06.451404 — evolutionary biology — Posted on 2021-07-08

3079 Area-based conservation planning in Japan: protected area network effectiveness to the post-2020 Global Biodiversity Framework

Shiono, T.; Kubota, Y.; Kusumoto, B.

10.1101/2021.07.07.451416 — ecology — Posted on 2021-07-08

3080 SARS-CoV-2 Neurotropism and Single Cell Responses in Brain Organoids Containing Innately Developing Microglia

Samudyata, ; Oliveira, A. O.; Malwade, S.; de Sousa, N. R.; Goparaju, S. K.; Orhan, F.; Steponaviciute, L.; Sheridan, S. D.; Perlis, R. H.; Rothfuchs, A. G.; Sellgren-Majkowitz, C.

10.1101/2021.07.07.451463 — neuroscience — Posted on 2021-07-08

3081 Impact of Fkbp5 x Early Life Adversity x Sex in Humanized Mice on Multidimensional Stress Responses and Circadian Rhythmicity

Nold, V.; Del Prete, D.; Blasius, A.; Harris, I.; Koros, E.; Peleh, T.; Hengerer, B.; Kolassa, I. T.; Slezak, M.; Alleres, K. A.

10.1101/2021.07.06.450863 — neuroscience — Posted on 2021-07-08

3082 Harmonic Passive Motion Paradigm

Tiseo, C.; Charitos, S. R.; Mistry, M.

10.1101/2021.07.06.451400 — neuroscience — Posted on 2021-07-08

3083 A billion synthetic 3D-antibody-antigen complexes enable unconstrained machine-learning formalized investigation of antibody specificity prediction

10.1101/2021.07.06.451258 — immunology — Posted on 2021-07-08

3084 GLOBAL EFFECTS OF A PD RISK-SNP AT THE ALPHA-SYNUCLEIN LOCUS

Prahl, J. D.; Pierce, S. E.; van der Schans, E. J.; Coetzee, G. A.; Tyson, T.

10.1101/2021.07.06.451330 — neuroscience — Posted on 2021-07-08

3085 Neural activity tracking identity and confidence in social information

Trudel, N.; Rushworth, M. F. S.; Wittmann, M. K.

10.1101/2021.07.06.449597 — neuroscience — Posted on 2021-07-08

3086 Stimulus-induced narrowband gamma oscillations are test-retest reliable in healthy elderly in human EEG

Ray, S.; Murty, D. V. P. S.; Kumar, W. S.; Manikandan, K.; Ramesh, R. G.; Purokayastha, S.; Javali, M.; Rao, N. P.

10.1101/2021.07.06.451226 — neuroscience — Posted on 2021-07-08

3087 A cell-sorting-based nano-scale pipeline for cell-type-specific proteomics in plants

Wang, H.; Li, R.; Rong, J.; Sang, T.; Kim, C.; Song, C.-P.; Dai, S.; Hsu, C.-C.; Wang, P.

10.1101/2021.07.06.451220 — plant biology — Posted on 2021-07-08

3088 Arabidopsis Topless-related 1 mitigates physiological damage and growth penalties of induced immunity

Griebel, T.; Lapin, D.; Locci, F.; Kracher, B.; Bautor, J.; Qiu, J.; Concia, L.; Benhamed, M.; Parker, J. E.

10.1101/2021.07.07.451397 — plant biology — Posted on 2021-07-08

3089 Phloem transport limitation in Huanglongbing affected sweet orange is dependent on phloem-limited bacteria and callose

Welker, S.; Pierre, M.; Santiago, J. P.; Dutt, M.; Vincent, C.; Levy, A.

10.1101/2021.07.07.451171 — plant biology — Posted on 2021-07-08

3090 Complete depletion of Arabidopsis linker histones impairs the correlations among chromatin compartmentalization, DNA methylation and gene expression

Sun, Z.; Li, M.; Zhnag, H.; Zhang, Y.; Ma, M.; Wang, P.; Fang, Y.; Li, G.; Fang, Y.

10.1101/2021.07.08.451606 — plant biology — Posted on 2021-07-08

3091 Approximation of the age distribution of cancer incidence using a mutational model

Tetearing, A. N.

10.1101/2021.07.06.451349 — cancer biology — Posted on 2021-07-08

3092 Efficient gradient boosting for prognostic biomarker discovery

Li, K.; Yao, S.; Zhang, Z.; Cao, B.; Wilson, C.; Kuan, P.; Zhu, R.; Wang, X.

10.1101/2021.07.06.451263 — bioinformatics — Posted on 2021-07-08

3093 Straintables: An application that extracts sequences fromgenome assemblies and generates dissimilarity matrices

Araujo, G.; Francis, R.; Ferreira, C.; Rangel, A.

10.1101/2021.07.06.451382 — bioinformatics — Posted on 2021-07-08

3094 Yuel: Compound-Protein Interaction Prediction with High Generalizability

Wang, J.; Dokholyan, N. V.

10.1101/2021.07.06.451043 — bioinformatics — Posted on 2021-07-08

3095 In silico analysis and molecular investigation of the nuclear shuttle protein-interacting kinase 1 (NIK1) in six Solanaceous species

Safaeizadeh, M.; Malpica, N.

10.1101/2021.07.06.451341 — bioinformatics — Posted on 2021-07-08

3096 Impairment Of Aversive Episodic Memories During COVID-19 Pandemic: The Impact Of Emotional Context On Memory Processes

Leon, C. S.; Bonilla, M.; Urreta Benitez, F. A.; Brusco, L. I.; Wang, J.; Forcato, C.

10.1101/2021.07.06.451294 — animal behavior and cognition — Posted on 2021-07-08

3097 Spatial heterogeneity in forest carbon storage affects priorities for reforestation

Chaplin-Kramer, R.; Johnson, J. A.; Sharp, R. P.; Chatterton, J.; Weil, C.; Baccini, A.; Sim, S.

10.1101/2021.07.06.450936 — ecology — Posted on 2021-07-08

3098 Effects of order on memory of event times

Naim, M.; Katkov, M.; Tsodyks, M.

10.1101/2020.09.11.289058 — neuroscience — Posted on 2021-07-08

3099 Involvement of sensory neuron-TRPV4 in acute and chronic itch behaviors

Fang, Q.; Wang, Z.; Suttle, A.; Chen, Y.

10.1101/2021.07.06.451366 — neuroscience — Posted on 2021-07-08

3100 Hurricane-induced population decrease in a Critically Endangered long-lived reptile

van den Burg, M. P.; Madden, H.; van Wagensveld, T.; Boman, E.

10.1101/2021.07.06.451308 — ecology — Posted on 2021-07-08

3101 Quantifying phase separation property of chromatin associated proteins under physiological conditions using anti-1,6-hexanediol index

Shi, M.; You, K.; Chen, T.; Hou, C.; Liang, Z.; Liu, M.; Wang, J.; Wei, T.; Qin, J.; Chen, Y.; Zhang, M. Q.; Li, T.

10.1101/2020.12.07.415489 — cell biology — Posted on 2021-07-08

3102 Wild lab: A naturalistic free viewing experiment reveals previously unknown EEG signatures of face processing.

Gert, A. L.; Ehinger, B. V.; Timm, S.; Kietzmann, T. C.; Koenig, P.

10.1101/2021.07.02.450779 — neuroscience — Posted on 2021-07-08

3103 A novel approach to the functional classification of retinal ganglion cells

Hilgen, G.; Kartsaki, E.; Kartysh, V.; Cessac, B.; Sernagor, E.

10.1101/2021.05.09.443323 — neuroscience — Posted on 2021-07-08

3104 Convergent consequences of parthenogenesis on stick insect genomes

Jaron, K. S.; Parker, D. J.; Anselmetti, Y.; Tran Van, P.; Bast, J.; Dumas, Z.; Figuet, E.; Francois, C. M.; Hayward, K.; Rossier, V.; Simion, P.; Robinson-Rechavi, M.; Galtier, N.; Schwander, T.

10.1101/2020.11.20.391540 — evolutionary biology — Posted on 2021-07-08

3105 Negative modulation of macroautophagy by HERPUD1 is counteracted by an increased ER-lysosomal network with impact in drug-induced stress cell survival

Vargas, G.; Cortes, O. H.; Arias-Munoz, E. N.; Hernandez-Galaz, S. F.; Cerda-Troncoso, C.; Hernandez-Torres, L.; Gonzalez, A. E.; Tatham, M.; Bustamante, H. A.; Retamal, C. E.; Cancino, J.; Varas-Godoy, M.; Hay, R. T.; Rojas-Fernandez, A.; Cavieres, V. A.; Burgos, P. V.

10.1101/2021.06.14.447273 — cell biology — Posted on 2021-07-08

3106 Members of a highly widespread bacteriophage family are hallmarks of metabolic syndrome gut microbiomes

de Jonge, P. A.; Wortelboer, K.; Scheithauer, T. P. M.; van den Born, B.-J. H.; Zwinderman, A. H.; Nobrega, F. L.; Dutilh, B. E.; Nieuwdorp, M.; Herrema, H.

10.1101/2021.03.30.437683 — microbiology — Posted on 2021-07-08

3107 Topographical relocation of adolescent sleep spindles reveals a new maturational pattern of the human brain

Gombos, F.; Bodizs, R.; Potari, A.; Bocskai, G.; Berencsi, A.; Szakacs, H.; Kovacs, I.

10.1101/2021.05.25.445646 — neuroscience — Posted on 2021-07-08

3108 Interrogation of genome-wide, experimentally dissected gene regulatory networks reveals mechanisms underlying dynamic cellular state control

Tan, X.; Worley, J.; Turunen, M.; Wong, K.; Fernandez, E. C.; Paull, E.; Jones, S.; Wang, J.; Noh, H.; Salvatori, B.; Chavez, A.; Califano, A.

10.1101/2021.06.28.449297 — systems biology — Posted on 2021-07-08

3109 Mechanosensitive Osteogenesis on Native Cellulose Scaffolds for Bone Tissue Engineering.

Leblanc Latour, M.; Pelling, A. E.

10.1101/2021.05.26.444470 — biophysics — Posted on 2021-07-08

3110 The molecular mechanism of cytoadherence to placenta or tumor cells through VAR2CSA from Plasmodium falciparum

Wang, W.; Wang, Z.; Yang, X.; Gao, Y.; Zhang, X.; Wang, W.; Zhao, L.; Zhang, J.; Jing, Q.; Xu, Q.; Cao, L.; Tian, Y.; Dai, A.; Sun, J.; Sun, L.; Jiang, L.; Chen, Z.; Wang, L.

10.1101/2021.07.06.451098 — biophysics — Posted on 2021-07-08

3111 Characterization of the radiation desiccation response regulon of the radioresistant bacterium Deinococcus radiodurans by integrative genomic analyses.

Eugenie, N.; Zivanovic, Y.; Lelandais, G.; Coste, G.; Bouthier de la Tour, C.; Bentchikou, E.; Servant, P.; Confalonieri, F.

10.1101/2021.07.07.451423 — genomics — Posted on 2021-07-08

3112 MG132 induces progerin clearance and improves disease phenotypes in fibroblasts of patients affected with Hutchinson-Gilford Progeria-like syndromes

HARHOURI, K.; CAU, P.; CASEY, F.; GUEDENON, K. M.; DOUBAJ, Y.; VAN MALDERGEM, L.; MEJIA-BALTODANO, G.; Bartoli, C.; De SANDRE-GIOVANNOLI, A.; LEVY, N.

10.1101/2021.04.14.439612 — genetics — Posted on 2021-07-08

3113 RNA degradation of blood reveals a time diagnostic window in a controlled environment

Elliott, C. I.; Stotesbury, T. E.; Shafer, A. B. A.

10.1101/2021.04.28.441847 — genetics — Posted on 2021-07-08

3114 3D viscoelastic drag forces contribute to cell shape changes during organogenesis in the zebrafish embryo

Sanematsu, P. C.; Erdemci-Tandogan, G.; Patel, H.; Retzlaff, E.; Amack, J. D.; Manning, L.

10.1101/2021.02.23.432503 — developmental biology — Posted on 2021-07-08

3115 Mapping the integration of sensory information across fingers in human sensorimotor cortex

Arbuckle, S. A.; Pruszynski, J. A.; Diedrichsen, J.

10.1101/2021.07.07.451552 — neuroscience — Posted on 2021-07-08

3116 Development of white matter tracts between and within the dorsal and ventral streams

Vinci-Booher, S.; Caron, B.; Bullock, D. N.; James, K. H.; Pestilli, F.

10.1101/2021.01.27.428423 — neuroscience — Posted on 2021-07-08

3117 Spatially resolved transcriptomics reveals unique gene signatures associated with human temporal cortical architecture and Alzheimer's pathology

Chen, S.; Chang, Y.; Li, L.; Acosta, D.; Morrison, C.; Wang, C.; Julian, D.; Hester, M. E.; Serrano, G. E.; Beach, T. G.; Ma, Q.; Fu, H.

10.1101/2021.07.07.451554 — neuroscience — Posted on 2021-07-08

3118 Cerebellar Dentate Connectivity Across Adulthood: A Large-Scale Resting State Functional Connectivity Investigation

Bernard, J. A.; Ballard, H.; Jacksons, T. B.

10.1101/2021.02.24.432761 — neuroscience — Posted on 2021-07-08

3119 Platform for Incisionless, Focal, and Multisite Brain Interventions

Webb, T. D.; Wilson, M. G.; Odéen, H.; Kubanek, J.

10.1101/2021.05.05.442844 — neuroscience — Posted on 2021-07-08

3120 KSTAR: An algorithm to predict patient-specific kinase activities from phosphoproteomic data

Crowl, S.; Jordan, B.; Ma, C.; Naegle, K. M.

10.1101/2021.07.06.451378 — systems biology — Posted on 2021-07-08

3121 Lightsheet Optical Tweezer (LOT) for Optical Manipulation of Microscopic Particles and Live Cells

Mondal, P. P.; Singh, A.; Joshi, P.; Basumatary, J.; Baro, N.

10.1101/2021.07.05.451038 — biophysics — Posted on 2021-07-08

3122 Ultra-fast insulin-pramlintide co-formulation for improved glucose management in diabetic rats

Maikawa, C. L.; Chen, P. C.; Vuong, E. T.; Nguyen, L. T.; Mann, J. L.; d'Aquino, A. I.; Lal, R. A.; Maahs, D. M.; Buckingham, B. A.; Appel, E. A.

10.1101/2021.04.12.439573 — bioengineering — Posted on 2021-07-07

3123 The myopathic transcription factor DUX4 induces the production of truncated RNA-bindingproteins in human muscle cells

Campbell, A. E.; Dyle, M. C.; Calviello, L.; Matheny, T.; Cortazar, M. A.; Forman, T.; Fu, R.; Gillen, A. E.; Floor, S. N.; Jagannathan, S.

10.1101/2021.06.28.450189 — genomics — Posted on 2021-07-07

3124 Hurricane-induced population decrease in a Critically Endangered long-lived reptile

van den Burg, M. P.; Madden, H.; van Wagensveld, T.; Boman, E.

10.1101/2021.07.06.451308 — ecology — Posted on 2021-07-07

3125 Effects of phenotypic variation on consumer coexistence and prey community structure

Hogle, S. L.; Hepolehto, I.; Ruokolainen, L.; Cairns, J.; Hiltunen, T.

10.1101/2021.06.09.447767 — ecology — Posted on 2021-07-07

3126 Size-dependent protein segregation creates a spatial switch for Notch signaling and function

Kwak, M.; Southard, K. M.; Kim, N. H.; Gopalappa, R.; Kim, W. R.; An, M.; Lee, H. J.; Kang, M. K.; Choi, S. H.; Farlow, J.; Georgakopoulos, A.; Robakis, N. K.; Seo, D.; Kim, H. B.; Kim, Y. H.; Cheon, J.; Gartner, Z. J.; Jun, Y.-w.

10.1101/2020.06.28.176560 — cell biology — Posted on 2021-07-07

3127 PreDarwinian evolution, prebiotic change: a principle of least selection

Yarus, M.

10.1101/2021.06.27.450095 — molecular biology — Posted on 2021-07-07

3128 Egress of human cytomegalovirus through multivesicular bodies

Flomm, F. J.; Soh, T. K.; Schneider, C.; Britt, H. M.; Thalassinos, K.; Pfitzner, S.; Reimer, R.; Gruenewald, K.; Bosse, J. B.

10.1101/2020.12.31.424954 — microbiology — Posted on 2021-07-07

3129 Fine-scale adaptations to environmental variation and growth strategies drive phyllosphere Methylobacterium diversity.

Leducq, J.-B.; Seyer-Lamontagne, E.; Condrain-Morel, D.; Bourret, G.; Sneddon, D.; Foster, J. A.; Marx, C. J.; Sullivan, J. M.; Shapiro, B. J.; Kembel, S. W.

10.1101/2021.06.04.447128 — microbiology — Posted on 2021-07-07

3130 Endosomal proteins NPC1 and NPC2 at African swine fever virus entry/fusion

Alonso, C.; Cuesta-Geijo, M. A.; Urquiza, J.; Del Puerto, A.; Garcia-Dorival, I.; Lasala, F.; Barrado-Gil, L.; Galindo, I.; Delgado, R.

10.1101/2021.07.07.451424 — microbiology — Posted on 2021-07-07

3131 Refined quantification of infection bottlenecks and pathogen dissemination with STAMPR

Hullahalli, K.; Pritchard, J. R.; Waldor, M. K.

10.1101/2021.04.28.441820 — microbiology — Posted on 2021-07-07

3132 O-specific antigen-dependent surface hydrophobicity mediates aggregate assembly type in Pseudomonas aeruginosa

Azimi, S.; Thomas, J.; Cleland, S.; Curtis, J. E.; Goldberg, J. B.; Diggle, S. P.

10.1101/2021.01.14.426723 — microbiology — Posted on 2021-07-07

3133 Life on leaves : uncovering temporal dynamics in Arabidopsis' leaf microbiota

Almario, J.; Mahmoudi, M.; Kroll, S.; Agler, M.; Placzek, A.; Mari, A.; Kemen, E.

10.1101/2021.07.06.450897 — microbiology — Posted on 2021-07-08

3134 Bcl-3 suppresses Th9 differentiation by regulating glutamine utilization

Tang, W.; Wang, H.; Philip, M. M.; Siebenlist, U.

10.1101/2021.07.06.451316 — immunology — Posted on 2021-07-08

3135 Gymnasts' ability to modulate bioelectric sensorimotor rhythms during kinesthetic motor imagery of sports non-specific movements

Sugino, H.; Ushiyama, J.

10.1101/2021.05.17.444451 — neuroscience — Posted on 2021-07-07

3136 Human fetal neural stem cell-derived astrocytes maintain glutamate transport after hypoxic injury in vitro

Shrivastava, V.; Dey, D.; Singal, C. M. S.; Jaiswal, P.; Singh, A.; Sharma, J. B.; Chattopadhyay, P.; Palanichamy, J. K.; Sinha, S.; Seth, P.; Sen, S.

10.1101/2021.05.17.444180 — neuroscience — Posted on 2021-07-07

3137 Intrinsic Network Activity Reflects the Fluctuating Experience of Tonic Pain

Deak, B.; Eggert, T.; Mayr, A.; Stankewitz, A.; Filippopulos, F.; Jahn, P.; Witkovsky, V.; Straube, A.; Schulz, E.

10.1101/2021.06.30.450591 — neuroscience — Posted on 2021-07-07

3138 Relationship between vestibular hair cell loss and deficits in two anti-gravity reflexes in the rat

Maroto, A. F.; Barrallo-Gimeno, A.; Llorens, J.

10.1101/2020.12.21.423804 — neuroscience — Posted on 2021-07-07

3139 Single-cell profiling of the human primary motor cortex in ALS and FTLD

10.1101/2021.07.07.451374 — neuroscience — Posted on 2021-07-07

3140 Prefrontal cortical connectivity mediates locus coeruleus noradrenergic regulation of inhibitory control in older adults

Tomassini, A.; Hezemans, F. H.; Ye, R.; Tsvetanov, K.; Wolpe, N.; Rowe, J.

10.1101/2021.06.29.450427 — neuroscience — Posted on 2021-07-08

3141 Co-regulating many properties by co-adjusting few ion channels increases ion channel correlations and the risk of regulation failure

Yang, J.; Shakil, H.; Ratte, S.; Prescott, S. A.

10.1101/2020.12.04.410787 — neuroscience — Posted on 2021-07-08

3142 Two evolutionary distinct effectors from a nematode and virus target RanGAP1 and 2 via the WPP domain to promote disease

Sukarta, O. C. A.; Munoz, A. D. G.; Slootweg, E. J.; Overmars, H.; van Schaik, C.; Pokhare, S.; Roosien, J.; Pomp, R.; Elashry, A.; Smant, G.; Goverse, A.

10.1101/2021.06.24.449730 — plant biology — Posted on 2021-07-07

3143 A robust field-based method to screen heat tolerance in wheat

Ullah, N.; Christopher, J.; Frederiks, T.; Ma, S.; Tan, D.; Chenu, K.

10.1101/2021.06.09.447803 — plant biology — Posted on 2021-07-07

3144 ABA homeostasis and long-distance translocation is redundantly regulated by ABCG ABA importers

Zhang, Y.; Vasuki, H.; Liu, J.; Bar, H.; Lazary, S.; Egbaria, A.; Ripper, D.; Charrier, L.; Aharoni, A.; Ragni, L.; Strader, L.; Sade, N.; Weinstain, R.; Geisler, M.; Shani, E.

10.1101/2021.05.12.443788 — plant biology — Posted on 2021-07-07

3145 Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors

Foster, J. B.; Griffin, C.; Rokita, J. L.; Stern, A.; Brimley, C.; Rathi, K.; Lane, M. V.; Buongervino, S. N.; Smith, T.; Martinez, D.; Wechsler-Reya, R.; Kariko, K.; Storm, P. B.; Barrett, D. M.; Resnick, A. C.; Maris, J. M.; Bosse, K. R.

10.1101/2021.07.06.451385 — cancer biology — Posted on 2021-07-07

3146 Oncogenic RABL6A promotes NF1-associated MPNST progression in vivo

Kohlmeyer, J. L.; Kaemmer, C. A.; Lingo, J. J.; Leidinger, M. R.; Meyerholz, D. K.; Tanas, M. R.; Dodd, R. D.; Quelle, D. E.

10.1101/2021.07.07.451475 — cancer biology — Posted on 2021-07-07

3147 A Non-Negative Tensor Factorization Approach to Deconvolute Epigenetic Microenvironment in Breast Cancer

Shi, M.; Sherpa, R.; Klindziuk, L.; Kriel, S.; Mollah, S.

10.1101/2020.12.01.406249 — cancer biology — Posted on 2021-07-07

3148 Analyzing Assay Specificity in Metabolomics using Unique Ion Signature Simulations

Shanthamoorthy, P.; Young, A.; Rost, H.

10.1101/2021.03.19.434579 — bioinformatics — Posted on 2021-07-07

3149 Genome-wide Disease Screening in Early Human Embryos with Primary Template-Directed Amplification

Xia, Y.; Gonzales-Pena, V.; Klein, D.; Luquette, J.; Puzon, L.; Siddiqui, N.; Reddy, V.; Park, P.; Behr, B.; Gawad, C.

10.1101/2021.07.06.451077 — bioengineering — Posted on 2021-07-07

3150 Dissolved oxygen minimally affects magnetic susceptibility in biologically relevant conditions

Fortier, V.; Levesque, I. R.

10.1101/2021.03.13.434266 — bioengineering — Posted on 2021-07-07

3151 Interactome analyses reveal profound proteasome structural and functional rearrangements throughout mammalian spermatogenesis

Zivkovic, D.; Sanchez Dafun, A.; Menneteau, T.; Schahl, A.; Lise, S.; Kervarrec, C.; Toste-Rego, A.; da Fonseca, P.; Chavent, M.; Pineau, C.; Schiltz, O.; Marcoux, J.; Bousquet, M.-P.

10.1101/2021.06.18.447862 — biochemistry — Posted on 2021-07-07

3152 Rapid speciation and karyotype evolution in Orthoptera

Palacios-Gimenez, O. M.

10.1101/2021.07.06.451348 — evolutionary biology — Posted on 2021-07-07

3153 Full-likelihood analysis of genomic data clarifies a complex history of species divergence and introgression in the erato-sara group of Heliconius butterflies

Thawornwattana, Y.; Seixas, F. A.; Yang, Z.; Mallet, J.

10.1101/2021.02.10.430600 — evolutionary biology — Posted on 2021-07-07

3154 Close-kin methods to estimate census size and effective population size

Waples, R. S.; Feutry, P.

10.1101/2021.01.19.427337 — evolutionary biology — Posted on 2021-07-07

3155 Hot and cold spots of pest-induced US urban tree death, 2020-2050

Hudgins, E. J.; Koch, F. H.; Ambrose, M. J.; Leung, B.

10.1101/2021.04.24.441210 — ecology — Posted on 2021-07-07

3156 Concerted dynamics between conserved histidines in the N-extein region regulates Mycobacterium tuberculosis SufB intein cleavage

Panda, S.; Nanda, A.; Sahu, N.; Ojha, D. K.; Pradhan, B.; Rai, A.; Suryawanshi, A. R.; Banavali, N.; Nayak, S.

10.1101/2021.07.07.451452 — molecular biology — Posted on 2021-07-07

3157 High-throughput functional analysis of CFTR and other apically localized channels in iPSC derived intestinal organoids

Xia, S.; Bozoky, Z.; Laselva, O.; DiPaola, M.; Ahmadi, S.; Jiang, J. X.; Pitstick, A.; Jiang, C.; Rotin, D.; Mayhew, C.; Jones, N. L.; Bear, C. E.

10.1101/2021.07.07.451180 — molecular biology — Posted on 2021-07-07

3158 UPF3A and UPF3B are redundant and modular activators of nonsense-mediated mRNA decay in human cells

Wallmeroth, D.; Boehm, V.; Lackmann, J.-W.; Altmueller, J.; Dieterich, C.; Gehring, N. H.

10.1101/2021.07.07.451444 — molecular biology — Posted on 2021-07-07

3159 Immune Lag Is a Major Cost of Prokaryotic Adaptive Immunity During Viral Outbreaks

Weissman, J. L.; Alseth, E. O.; Meaden, S.; Westra, E. R.; Fuhrman, J. A.

10.1101/2020.09.30.321075 — microbiology — Posted on 2021-07-07

3160 SAFA facilitates chromatin opening of immune genes through interacting with nascent antiviral RNAs

Cao, L.; Li, Y.; Luo, Y.; Guo, X.; Li, S.; Zhang, Z.; Gao, F.; Zhang, Q.; Ji, X.; Gao, X.; Wang, Y.; Zhao, Y.; You, F.; Liu, S.; Li, J.

10.1101/2021.07.06.451336 — immunology — Posted on 2021-07-07

3161 Clostridium difficile Toxin B activates the NLRP3 inflammasome in human macrophages, demonstrating a novel regulatory mechanism for the Pyrin inflammasome

Mangan, M. S. J.; Gorki, F.; Krause, K.; Heinz, A.; Ebert, T.; Jahn, D.; Hiller, K.; Hornung, V.; Mauer, M.; Schmidt, F. I.; Gerhard, R.; Latz, E.

10.1101/2021.07.07.451422 — immunology — Posted on 2021-07-07

3162 Adult medial habenula neurons require GDNF receptor GFRalpha1 for synaptic stability and function

Fernandez-Suarez, D.; Krapacher, F.; Pietrajtis, K.; Andersson, A.; Kisiswa, L.; Diana, M.; Ibanez, C.

10.1101/2021.07.07.451421 — neuroscience — Posted on 2021-07-07

3163 Chronic CNS Pathology is Associated with Abnormal Collagen Deposition and Fibrotic-like Changes

Macapagal, D.; Cann, J.; Zerrouki, K.; Dacosta, K.; Wang, J.; Connor, J.; Cresswell, G.; Davidson, T.

10.1101/2021.07.06.451298 — neuroscience — Posted on 2021-07-07

3164 A unified theory of E/I synaptic balance, quasicritical neuronal avalanches and asynchronous irregular spiking

Girardi-Schappo, M.; Galera, E. F.; Carvalho, T. T. A.; Brochini, L.; Kamiji, N. L.; Roque, A. C.; Kinouchi, O.

10.1101/2020.12.17.423201 — neuroscience — Posted on 2021-07-07

3165 Multivalent designed proteins protect against SARS-CoV-2 variants of concern

Hunt, A. C.; Case, J. B.; Park, Y.-J.; Cao, L.; Wu, K.; Walls, A. C.; Liu, Z.; Bowen, J. E.; Yeh, H.-W.; Saini, S.; Helms, L.; Zhao, Y. T.; Hsiang, T.-Y.; Starr, T. N.; Goreshnik, I.; Kozodoy, L.; Carter, L.; Ravichandran, R.; Green, L. B.; Matochko, W. L.; Thomson, C. A.; Vogeli, B.; Kruger-Gericke, A.; VanBlargan, L. A.; Chen, R. E.; Ying, B.; Bailey, A. L.; Kafai, N. M.; Boyken, S.; Ljubetic, A.; Edman, N.; Ueda, G.; Chow, C.; Addetia, A.; Panpradist, N.; Gale, M.; Freedman, B.; Lutz, B.; Bloom, J. D.; Ruohola-Baker, H.; Whelan, S. P. J.; Stewart, L.; Diamond, M. S.; Veesler, D.; Jewett, M.

10.1101/2021.07.07.451375 — synthetic biology — Posted on 2021-07-07

3166 Synthetic genomic reconstitution reveals principles of mammalian Hox cluster regulation

Pinglay, S.; Bulajic, M.; Rahe, D. P.; Huang, E.; Brosh, R.; German, S.; Cadley, J. A.; Rieber, L.; Easo, N.; Mahony, S.; Maurano, M. T.; Holt, L. J.; Mazzoni, E. O.; Boeke, J. D.

10.1101/2021.07.07.451065 — synthetic biology — Posted on 2021-07-07

3167 Identification of the functions of 4-coumarate-CoA ligase/ acyl-CoA synthetase paralogs in potato

Valinas, M. A.; ten Have, A.; Andreu, A. B.

10.1101/2021.07.06.451337 — plant biology — Posted on 2021-07-07

3168 Optimization of the TeraTox assay for preclinical teratogenicity assessment

Jaklin, M.; Zhang, J. D.; Schaefer, N.; Clemann, N.; Barrow, P.; Kueng, E.; Sach-Peltason, L.; McGinnis, C.; Leist, M.; Kustermann, S.

10.1101/2021.07.06.451364 — pharmacology and toxicology — Posted on 2021-07-07

3169 Re-convolving the compositional landscape of primary and recurrent glioblastoma using single nucleus RNA sequencing

Al-Dalahmah, O.; Argenziano, M.; Boyett, D.; Save, A.; Mahajan, A.; Khan, F.; Tuddenham, J.; goldberg, a. r.; Dovas, A.; Banu, M.; Furnari, J.; Sudhakar, T.; Bush, E.; Lassman, A.; Bruce, J.; Sims, P.; Menon, V.; Canoll, P.

10.1101/2021.07.06.451295 — pathology — Posted on 2021-07-07

3170 m6A demethylase ALKBH5 promotes tumor cell proliferation by destabilizing IGF2BPs target genes and worsens the prognosis of patients with non-small cell lung cancer

Tsuchiya, K.; Yoshimura, K.; Iwashita, Y.; Inoue, Y.; Ohta, T.; Watanabe, H.; Yamada, H.; Kawase, A.; Tanahashi, M.; Ogawa, H.; Funai, K.; Shinmura, K.; Suda, T.; Sugimura, H.

10.1101/2021.07.06.451216 — cancer biology — Posted on 2021-07-07

3171 Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes

Killer, M.; Wald, J.; Pieprzyk, J.; Marlovits, T. C.; Loew, C.

10.1101/2021.07.07.451464 — biophysics — Posted on 2021-07-07

3172 CAT, AGTR2, L-SIGN and DC-SIGN are potential receptors for the entry of SARS-CoV-2 into human cells

Guo, D.; Guo, R.; Li, Z.; Zhang, Y.; Zheng, W.; Huang, X.; Aziz, T.; Zhang, Y.; Liu, L.

10.1101/2021.07.07.451411 — bioinformatics — Posted on 2021-07-07

3173 Wireless endovascular nerve stimulation with a millimeter-sized magnetoelectric implant

Chen, J. C.; Kan, P.; Yu, Z.; Alrashdan, F.; Garcia, R.; Singer, A. C.; Lai, C. S. E.; Avants, B.; Crosby, S.; Felicella, M. M.; Robledo, A.; Hartgerink, J. D.; Sheth, S. A.; Yang, K.; Robinson, J. T.

10.1101/2021.07.06.450036 — bioengineering — Posted on 2021-07-07

3174 Serine ADP-ribosylation marks nucleosomes for ALC1-dependent chromatin remodeling

Mohapatra, J.; Tashiro, K.; Beckner, R. L.; Sierra, J.; Kilgore, J. A.; Williams, N. S.; Liszczak, G.

10.1101/2021.07.06.449314 — biochemistry — Posted on 2021-07-07

3175 Rapid extraction and kinetic analysis of protein complexes from single cells

Sarıkaya, S.; Dickinson, D. J.

10.1101/2021.07.07.451367 — biochemistry — Posted on 2021-07-07

3176 The E. coli helicase does not use ATP during replication.

Spenkelink, L. M.; Spinks, R. R.; Jergic, S.; Lewis, J. S.; Dixon, N. E.; van Oijen, A. M.

10.1101/2021.07.07.451541 — biochemistry — Posted on 2021-07-07

3177 A single-cell transcriptomic atlas characterizes liver non-parenchymal cells in healthy and diseased mice

Wang, Z.; Qian, J.; Lu, X.; Zhang, P.; Guo, R.; Lou, H.; Zhang, S.; Yang, J.; Fan, X.

10.1101/2021.07.06.451396 — genomics — Posted on 2021-07-07

3178 Microchromosomes are building blocks of bird, reptile and mammal chromosomes

Waters, P. D.; Patel, H. R.; Ruiz-Herrera, A.; Alvarez-Gonzalez, L.; Lister, N. C.; Simakov, O.; Ezaz, T.; Kaur, P.; Frere, C.; Grutzner, F.; Georges, A.; Graves, J. A. M.

10.1101/2021.07.06.451394 — genomics — Posted on 2021-07-07

3179 Receptor-binding domain recombinant protein RBD219-N1C1 on alum-CpG induces broad protection against SARS-CoV-2 variants of concern

Pollet, J.; Strych, U.; Chen, W.-H.; Versteeg, L.; Keegan, B.; Zhan, B.; Wei, J.; Liu, Z.; Lee, J.; Kundu, R.; Adhikari, R.; Poveda, C.; Villar, M. J.; Lopez, B.; Gillespie, P. M.; Ronca, S.; Kimata, J. T.; Reers, M.; Paradkar, V.; Hotez, P.; Bottazzi, M. E.

10.1101/2021.07.06.451353 — molecular biology — Posted on 2021-07-07

3180 Structural basis of target DNA recognition by CRISPR-Cas12k for RNA-guided DNA transposition

Xiao, R.; Wang, S.; Han, R.; Li, Z.; Gabel, C.; Mukherjee, I. A.; Chang, L.

10.1101/2021.07.07.451486 — molecular biology — Posted on 2021-07-07

3181 Immunogenicity of low dose prime-boost vaccination of mRNA vaccine CV07050101 in non-human primates

van Doremalen, N.; Fischer, R.; Schulz, J.; Holbrook, M.; Smith, B.; Lovaglio, J.; Petsch, B.; Munster, V.

10.1101/2021.07.07.451505 — microbiology — Posted on 2021-07-07

3182 Genome-wide association study reveals putative bacterial risk factors for cavitary Mycobacterium avium complex lung disease

Yano, H.; Nishiuchi, Y.; Arikawa, K.; Ota, A.; Miki, M.; Maruyama, F.; Kida, H.; Kitada, S.; Iwamoto, T.

10.1101/2021.07.06.451401 — microbiology — Posted on 2021-07-07

3183 Protease activities of vaginal Porphyromonas species disrupt coagulation and extracellular matrix in the cervicovaginal niche

Lithgow, K. V.; Buchholz, V. C. H.; Ku, E.; Konschuh, S.; D'Aubeterre, A.; Sycuro, L. K.

10.1101/2021.07.07.447795 — microbiology — Posted on 2021-07-07

3184 Defining the Immune Responses for SARS-CoV-2-Human Macrophage Interactions

Mostafa, M.; Yeapuri, P.; Machhi, J.; Olson, K.; Shahjin, F.; Zhou, Y.; Jingjing, L.; Pandey, K.; Acharya, A.; Byrareddy, S.; Mosley, L.; Gendelman, H.

10.1101/2021.07.07.449660 — immunology — Posted on 2021-07-07

3185 A single full-length VAR2CSA ectodomain variant purifies broadly neutralizing antibodies against placental malaria isolates

Doritchamou, J. Y. A.; Renn, J. P.; Jenkins, B.; Fried, M.; Duffy, P. E.

10.1101/2021.07.07.451420 — immunology — Posted on 2021-07-07

3186 The methamphetamine-induced RNA targetome of hnRNP H in Hnrnph1 mutants showing reduced dopamine release and behavior

Ruan, Q. T.; Rieger, M. A.; Lynch, W. B.; Cox, J. W.; Beierle, J. A.; Yao, E. J.; Kandola, A.; Chen, M. M.; Kelliher, J. C.; Babbs, R. K.; Ash, P. E. A.; Wolozin, B.; Szumlinski, K. K.; Johnson, W. E.; Dougherty, J.; Bryant, C. D.

10.1101/2021.07.06.451358 — neuroscience — Posted on 2021-07-07

3187 Comparative Transcriptomics of Tropical Woody Plants Supports Fast and Furious Strategy along the Leaf Economics Spectrum in Lianas.

Sezen, U. U.; Worthy, S. J.; Umana, M. N.; Davies, S. J.; McMahon, S. M.; Swenson, N. G.

10.1101/2021.07.06.451334 — plant biology — Posted on 2021-07-07

3188 Multi-modal locomotor costs explain sexual size but not shape dimorphism in a leaf-mimicking insect

Boisseau, R. P.; Buscher, T. H.; Klawitter, L. J.; Gorb, S. N.; Emlen, D. J.; Tobalske, B. W.

10.1101/2021.07.06.451325 — ecology — Posted on 2021-07-07

3189 Biomechanical study of cellulose scaffolds for bone tissue engineering in vivo and in vitro.

Leblanc Latour, M.; Tarar, M.; Hickey, R. J.; Cuerrier, C. M.; Catelas, I.; Pelling, A.

10.1101/2021.07.07.451476 — bioengineering — Posted on 2021-07-07

3190 Epigenetic scores for the circulating proteome as tools for disease prediction

Gadd, D. A.; Hillary, R. F.; McCartney, D. L.; Zaghlool, S. B.; Stevenson, A. J.; Nangle, C.; Campbell, A.; Flaig, R.; Harris, S. E.; Walker, R. M.; Shi, L.; Tucker-Drob, E. M.; Gieger, C.; Peters, A.; Waldenberger, M.; Graumann, J.; McRae, A. F.; Deary, I. J.; Porteous, D. J.; Hayward, C.; Visscher, P. M.; Cox, S. R.; Evans, K. L.; McIntosh, A. M.; Suhre, K.; Marioni, R. E.

10.1101/2020.12.01.404681 — genomics — Posted on 2021-07-07

3191 Molecular adaptation to folivory and the conservation implications for Madagascar's lemurs

Guevara, E. E.; Greene, L. K.; Blanco, M. B.; Farmer, C.; Ranaivonasy, J.; Ratsirarson, J.; Mahefarisoa, K.; Rajaonarivelo, T.; Rakotondrainibe, H.; Junge, R.; Williams, C.; Rambeloson, E.; Rasoanaivo, H.; Rahalinarivo, V.; Andrianandrianina, L.; Clayton, J.; Rothman, R.; Lawler, R. R.; Bradley, B. J.; Yoder, A. D.

10.1101/2021.07.06.451309 — ecology — Posted on 2021-07-07

3192 Bayesian estimation of population size and overlap from random subsamples

Johnson, E. K.; Larremore, D. B.

10.1101/2021.07.06.451319 — ecology — Posted on 2021-07-07

3193 S18-phosphorylation of USP7 regulates interaction with TCEAL4 that defines specific complexes and potentially distinct functions.

Querques, F.; Darling, S.; Cheetham-Wilkinson, I.; Kim, R.; Hapangama, D. K.; Sixma, T. K.; Coulson, J. M.

10.1101/2021.07.07.451439 — cell biology — Posted on 2021-07-07

3194 Myeloid-to-mesenchymal NGF-p75 signaling coordinates skeletal cell migration during repair

Xu, J.; Li, Z.; Tower, R. J.; Negri, S.; Wang, Y.; Meyers, C. A.; Sono, T.; Qin, Q.; Lu, A.; McCarthy, E. F.; Clemens, T. L.; James, A. W.

10.1101/2021.07.07.451468 — cell biology — Posted on 2021-07-07

3195 Dynamic Apical-Basal Enrichment of the F-Actin during Cytokinesis in Arabidopsis Cells Embedded in Their Tissues

Lebecq, A.; Fangain, A.; Boussaroque, A.; Caillaud, M.-C.

10.1101/2021.07.07.451432 — cell biology — Posted on 2021-07-07

3196 Distinct mitochondrial remodeling during early cardiomyocyte development in a human-based stem cell model

Mostafavi, S.; Balafkan, N.; Pettersen, I. K. N.; Nido, G. S.; Siller, R.; Tzoulis, C.; Sullivan, G.; Bindoff, L. A.

10.1101/2021.07.07.451436 — cell biology — Posted on 2021-07-07

3197 Nucleolar NOC1 controls protein synthesis and cell competition in Drosophila

Destefanis, F.; Manara, V.; Santarelli, S.; Zola, S.; Brambilla, M.; Viola, G.; Maragno, P.; Viero, G.; Pasini, M. E.; Penzo, M.; Bellosta, P.

10.1101/2021.07.06.451100 — cell biology — Posted on 2021-07-07

3198 Oxidative phosphorylation safeguards pluripotency via UDP-N-acetylglucosamine

Cao, J.; Li, M.; Liu, K.; Shi, X.; Sui, N.; Yao, Y.; Wang, X.; Tan, S.; Zhao, Q.; Wang, L.; Chai, X.; Zhang, L.; Liu, C.; Li, X.; Chang, Z.; Li, D.; Zhao, T.

10.1101/2021.07.06.451381 — cell biology — Posted on 2021-07-07

3199 Dynamics in Fip1 regulate eukaryotic mRNA 3'-end processing

Kumar, A.; Yu, C. W.; Rodriguez-Molina, J. B.; Li, X.-H.; Freund, S. M.; Passmore, L. A.

10.1101/2021.07.07.451483 — molecular biology — Posted on 2021-07-07

3200 Spontaneous pauses in firing of external pallidum neurons are associated with exploratory behavior

Kaplan, A.; Mizrahi-Kliger, A. D.; Rappel, P.; Iskhakova, L.; Fonar, G.; Israel, Z.; Bergman, H.

10.1101/2021.07.06.451269 — neuroscience — Posted on 2021-07-07

3201 Disentangling Age and Schooling Effects on Inhibitory Control Development: An fNIRS Investigation

McKay, C.; Wijeakumar, S.; Rafesetder, E.; Shing, Y. L.

10.1101/2021.07.06.451315 — neuroscience — Posted on 2021-07-07

3202 Mapping circuit dynamics during function and dysfunction

Gorur-Shandilya, S.; Cronin, E. M.; Schneider, A. C.; Haddad, S. A.; Rosenbaum, P.; Bucher, D.; Nadim, F.; Marder, E.

10.1101/2021.07.06.451370 — neuroscience — Posted on 2021-07-07

3203 Simvastatin Therapy Attenuates Memory Deficits that Associate with Brain Monocyte Infiltration in Chronic Hypercholesterolemia

Don-Doncow, N.; Vanherle, L.; Matthes, F.; Kragh Petersen, S.; Matuskova, H.; Rattik, S.; Hartlova, A.; Meissner, A.

10.1101/2020.05.15.098236 — physiology — Posted on 2021-07-07

3204 BAM15 treats mouse sepsis and sepsis-AKI, linking circulating mitochondrial DNA and tubule reactive oxygen species

Tsuji, N.; Tsuji, T.; Yamashita, T.; Hu, X.; Yuen, P. S. T.; Star, R. A.

10.1101/2021.07.06.451287 — pharmacology and toxicology — Posted on 2021-07-07

3205 Breast invasive ductal carcinoma classification on whole slide images with weakly-supervised and transfer learning

Kanavati, F.; Tsuneki, M.

10.1101/2021.07.06.451320 — pathology — Posted on 2021-07-07

3206 Force generation by protein-DNA co-condensation

Quail, T.; Golfier, S.; Elsner, M.; Ishihara, K.; Renger, R.; Julicher, F.; Brugues, J.

10.1101/2020.09.17.302299 — biophysics — Posted on 2021-07-07

3207 β-adrenergic stimulation synchronizes a broad spectrum of action potential firing rates of cardiac pacemaker cells towards a higher population average

Kim, M. S.; Monfredi, O.; Maltseva, L. A.; Lakatta, E. G.; Maltsev, V. A.

10.1101/2021.07.06.451302 — biophysics — Posted on 2021-07-07

3208 DynaTMT: A user-friendly tool to process combined SILAC/TMT data

Klann, K.; Krause, D.; Muench, C.

10.1101/2021.07.06.451268 — bioinformatics — Posted on 2021-07-07

3209 MSNovelist: De novo structure generation from mass spectra

Stravs, M. A.; Dührkop, K.; Böcker, S.; Zamboni, N.

10.1101/2021.07.06.450875 — bioinformatics — Posted on 2021-07-07

3210 MONI: A Pangenomics Index for Finding MEMs

Rossi, M.; Oliva, M.; Langmead, B.; Gagie, T.; Boucher, C.

10.1101/2021.07.06.451246 — bioinformatics — Posted on 2021-07-07

3211 DyNeuMo Mk-1: Design and Pilot Validation of an Investigational Motion-Adaptive Neurostimulator with Integrated Chronotherapy

Zamora, M.; Toth, R.; Morgante, F.; Ottaway, J.; Gillbe, T.; Martin, S.; Lamb, G.; Noone, T.; Benjaber, M.; Nairac, Z.; Constandinou, T. G.; Herron, J.; Aziz, T. Z.; Gillbe, I.; Green, A. L.; Pereira, E.; Denison, T.

10.1101/2020.09.10.292284 — bioengineering — Posted on 2021-07-07

3212 Proteolytic Activation of Human-specific Olduvai Domains by the Furin Protease

Pacheco, A.; Issaian, A.; Davis, J.; Anderson, N.; Nemkov, T.; Vögeli, B.; Hansen, K.; Sikela, J.

10.1101/2021.07.06.450945 — evolutionary biology — Posted on 2021-07-07

3213 Predictability and parallelism in the contemporary evolution of hybrid genomes

Langdon, Q. K.; Powell, D. L.; Kim, B.; Banerjee, S. M.; Payne, C.; Dodge, T. O.; Moran, B.; Fascinetto-Zago, P.; Schumer, M.

10.1101/2021.07.06.451368 — evolutionary biology — Posted on 2021-07-07

3214 Phylogenomics of a new fungal phylum reveals multiple waves of reductive evolution across Holomycota

Galindo, L. J.; Lopez-Garcia, P.; Torruella, G.; Karpov, S. A.; Moreira, D.

10.1101/2020.11.19.389700 — evolutionary biology — Posted on 2021-07-07

3215 Hurricane-induced population decrease in a Critically Endangered long-lived reptile

van den Burg, M. P.; Madden, H.; van Wagensveld, T.; Boman, E.

10.1101/2021.07.06.451308 — ecology — Posted on 2021-07-07

3216 Grizzly bear toe amputation due to seasonal overlap with furbearer trapping in southeast British Columbia

Lamb, C.; Smit, L.; Vander Vennen, L.; Mowat, G.; Proctor, M.; McLellan, B.

10.1101/2021.07.06.450999 — ecology — Posted on 2021-07-07

3217 Ultrastructural readout of in vivo synaptic activity for functional connectomics.

Simon, A.; Roth, A.; Sheridan, A.; Fisek, M.; Marra, V.; Racca, C.; Funke, J.; Staras, K.; Hausser, M.

10.1101/2021.07.07.451278 — neuroscience — Posted on 2021-07-07

3218 DACO: Distortion/artefact correction for diffusion MRI data in an integrated framework

Hsu, Y.-C.; Tseng, W.-Y. I.

10.1101/2021.07.06.450481 — neuroscience — Posted on 2021-07-07

3219 History of winning and hierarchy landscape influence stress susceptibility in mice

LeClair, K. B.; Chan, K. L.; Kaster, M. P.; Parise, L. F.; Burnett, C. J.; Russo, S.

10.1101/2021.07.06.451249 — neuroscience — Posted on 2021-07-07

3220 Parafoveal words can modulate sentence meaning: Electrophysiological evidence from an RSVP-with-flanker task

Li, N.; Dimigen, O.; Sommer, W.; Wang, S.

10.1101/2021.07.06.451256 — neuroscience — Posted on 2021-07-07

3221 Investigating the Impact of Offer Frame Manipulations On Responders Playing The Ultimatum Game

Fabre, E. F.; Rumiati, R.; Cacciari, C.; Borau, S.; Causse, M.; Lotto, L.

10.1101/2021.07.06.451289 — neuroscience — Posted on 2021-07-07

3222 The EEG spectral fingerprints of meditation and mind wandering differ between experienced meditators and novices

Rodriguez-Larios, J.; Bracho Montes de Oca, E. A.; Alaerts, K.

10.1101/2021.07.06.451305 — neuroscience — Posted on 2021-07-07

3223 Automatic decomposition of electrophysiological data into distinct non-sinusoidal oscillatory modes

Fabus, M. S.; Quinn, A. J.; Warnaby, C. E.; Woolrich, M. W.

10.1101/2021.07.06.451245 — neuroscience — Posted on 2021-07-07

3224 Behavioral, Anatomical and Genetic Convergence of Affect and Cognition in Superior Frontal Cortex

Kraljevic, N.; Schaare, H. L.; Eickhoff, S. B.; Kochunov, P.; Yeo, B. T. T.; Kharabian Masouleh, S.; Valk, S. L.

10.1101/2020.12.03.401414 — neuroscience — Posted on 2021-07-07

3225 Galleria mellonella as a novel eco-friendly in vivo approach for the assessment of the toxicity of medicinal plants

Joseph Arsene, M. M.; Viktorovna, P. I.; Linda Davares, A. K.

10.1101/2021.07.06.451318 — pharmacology and toxicology — Posted on 2021-07-07

3226 Recovering Escherichia coli plasmids in the absence of long-read sequencing data

Paganini, J. A.; Plantinga, N. L.; Arredondo-Alonso, S.; Willems, R. J. L.; Schurch, A. C.

10.1101/2021.07.06.451259 — bioinformatics — Posted on 2021-07-07

3227 A Deep Learning Framework for Prediction of Clinical Drug Response of Cancer Patients and Identification of Drug Sensitivity Biomarkers using Preclinical Samples

Hostallero, D. E.; Wei, L.; Wang, L.; Cairns, J.; Emad, A.

10.1101/2021.07.06.451273 — bioinformatics — Posted on 2021-07-07

3228 What is behavior? No seriously, what is it?

Calhoun, A.; El Hady, A.

10.1101/2021.07.04.451053 — animal behavior and cognition — Posted on 2021-07-07

3229 Traip Mitotic Function Controls Brain Size

O'Neill, R. S.; Rusan, N. M.

10.1101/2021.07.07.451466 — developmental biology — Posted on 2021-07-07

3230 The orexigenic force of olfactory palatable food cues in sated rats

Peris-Sampedro, F.; Stoltenborg, I.; Le May, M. V.; Sole-Navais, P.; Adan, R. A.; Dickson, S. L.

10.1101/2021.07.06.451251 — neuroscience — Posted on 2021-07-07

3231 AI-driven prediction of SARS-CoV-2 variant binding trends from atomistic simulations

Capponi, S.; Wang, S.; Navarro, E. J.; Bianco, S.

10.1101/2021.03.07.434295 — biophysics — Posted on 2021-07-07

3232 SHIMS 3.0: Highly efficient single-haplotype iterative mapping and sequencing using ultra-long nanopore reads

Bellott, D. W.; Cho, T.-J.; Jackson, E. K.; Skaletsky, H.; Hughes, J. F.; Page, D. C.

10.1101/2020.09.18.303735 — genomics — Posted on 2021-07-07

3233 DiMeLo-seq: a long-read, single-molecule method for mappingprotein-DNA interactions genome-wide

Altemose, N.; Maslan, A.; Smith, O. K.; Sundararajan, K.; Brown, R. R.; Detweiler, A. M.; Neff, N.; Miga, K. H.; Straight, A. F.; Streets, A.

10.1101/2021.07.06.451383 — genomics — Posted on 2021-07-07

3234 LI-Seq: A Cost-Effective, Low Input DNA method for Whole Genome Library Preparation

Schweizer, T. M.; Ruegg, K. C.; DeSaix, M. G.

10.1101/2021.07.06.451326 — genetics — Posted on 2021-07-07

3235 Adaptive foraging behaviour increases vulnerability to climate change

Gauzens, B.; Rosenbaum, B.; Kalinkat, G.; Boy, T.; Jochum, M.; Kortsch, S.; O'Gorman, E. J.; Brose, U.

10.1101/2021.05.05.442768 — ecology — Posted on 2021-07-07

3236 Heat-treated virus inactivation rate depends strongly on treatment procedure: illustration with SARS-CoV-2

Gamble, A.; Fischer, R. J.; Morris, D. H.; Yinda, K. C.; Munster, V. J.; Lloyd-Smith, J. O.

10.1101/2020.08.10.242206 — microbiology — Posted on 2021-07-07

3237 Spike frequency adaptation supports network computations on temporally dispersed information

Salaj, D.; Subramoney, A.; Kraisnikovic, C.; Bellec, G.; Legenstein, R.; Maass, W.

10.1101/2020.05.11.081513 — neuroscience — Posted on 2021-07-07

3238 Exploring the Inner Workings of Neuron Circuits That Exhibit Persistent Activity To Explain How Working Memory and Executive Function Are Implemented in The Brain

Gomez, P.; Gomez, J.; Gomez, A.

10.1101/2021.07.05.451167 — neuroscience — Posted on 2021-07-07

3239 Dual-lipid metabolomics revealed the communication of MTB or MB with Bovine alveolar macrophages in lipid metabolisms

Gao, W.; Cai, Y.; Zhang, G.; Wang, X.; Wang, J.; Li, Y.; Wang, Y.

10.1101/2021.07.06.451399 — microbiology — Posted on 2021-07-07

3240 Visual perturbation of balance suggests impaired neuromuscular stability but intact visuo-motor control in Parkinson's disease

Engel, D.; Student, J.; Schwenk, J. C. B.; Morris, A. P.; Waldthaler, J.; Timmermann, L.; Bremmer, F.

10.1101/2021.07.05.451110 — neuroscience — Posted on 2021-07-07

3241 Entering into a self-regulated learning mode prevents detrimental effect of feedback removal on memory

Vavra, P.; Sokolovic, L.; Porcu, E.; Ripolles, P.; Rodriguez-Fornells, A.; Noesselt, T.

10.1101/2021.07.02.450865 — neuroscience — Posted on 2021-07-07

3242 TimTrack: A drift-free algorithm for estimating geometric muscle features from ultrasound images

van der Zee, T. J.; Kuo, A. D.

10.1101/2020.08.23.263574 — physiology — Posted on 2021-07-07

3243 Is male dimorphism under sexual selection in humans? A meta-analysis

Lidborg, L. H.; Cross, C. P.; Boothroyd, L. G.

10.1101/2020.03.06.980896 — evolutionary biology — Posted on 2021-07-07

3244 Alkane-priming of Beauveria bassiana strains to improve biocontrol of the redbanded stink bug Piezodorus guildinii and the bronze bug Thaumastocoris peregrinus

Sessa, L.; Pedrini, N.; Altier, N.; Abreo, E.

10.1101/2021.07.06.451384 — microbiology — Posted on 2021-07-07

3245 Genomes of novel Myxococcota reveal severely curtailed machineries for predation and cellular differentiation

Murphy, C.; Cavalliere, C.; Cornell, J.; Higgs, J.; Mares, S.; Meili, C.; Andreev, V.; Bircher, N.; Decker, T.; Dohmen, R.; Eichhorn, A.; Grinnell, A.; Jett, C.; Khadka, R.; Liu, J.; Mukhtar, H.; Pratt, C.; Elshahed, M. S.; Youssef, N. H.

10.1101/2021.07.06.451402 — microbiology — Posted on 2021-07-07

3246 An Autoantigen Profile from Jurkat T-Lymphoblasts Provides a Molecular Guide for Investigating Autoimmune Sequelae of COVID-19

Wang, J. Y.; Zhang, W.; Roehrl, M. W.; Roehrl, V. B.; Roehrl, M. H.

10.1101/2021.07.05.451199 — immunology — Posted on 2021-07-07

3247 Investigating the conformational dynamics of SARS-CoV-2 NSP6 protein with emphasis on non-transmembrane 91-112 & 231-290 regions

Kumar, A.; Kumar, P.; Saumya, K. U.; Giri, R.

10.1101/2021.07.06.451329 — biophysics — Posted on 2021-07-07

3248 Genome Profiling of SARS-CoV-2 in Indonesia, ASEAN and the Neighbouring East Asian Countries: Features, Challenges and Achievements

Cahyani, I.; Putro, E. W.; Ridwanuloh, A. M.; Wibowo, S.; Hariyatun, ; Syahputra, G.; Akbariani, G.; Utomo, A. R.; Ilyas, M.; Loose, M. W.; Kusharyoto, W.; Susanti, S.

10.1101/2021.07.06.451270 — genomics — Posted on 2021-07-07

3249 Trans-generational effect of protein restricted diet on adult body and wing size of Drosophila melanogaster

Krittika, S.; Yadav, P.

10.1101/2020.02.17.952101 — evolutionary biology — Posted on 2021-07-07

3250 Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection

Wang, R.; Hume, A.; Beermann, M. L.; Simone-Roach, C.; Lindstrom-Vautrin, J.; Le Suer, J.; Huang, J.; Olejnik, J.; Villacorta-Martin, C.; Bullitt, E.; Hinds, A.; Ghaedi, M.; Werder, R.; Abo, K.; Wilson, A.; Muhlberger, E.; Kotton, D. N.; Hawkins, F. J.

10.1101/2021.07.06.451340 — cell biology — Posted on 2021-07-07

3251 Synthesis of modified nucleotide polymers by the poly(U) polymerase Cid1: Application to direct RNA sequencing on nanopores.

Vo, J.; Mulroney, L.; Quick-Cleveland, J.; Jain, M.; Akeson, M.; Ares, M.

10.1101/2021.07.06.451372 — molecular biology — Posted on 2021-07-07

3252 The core root microbiome of Spartina alterniflora is predominated by sulfur-oxidizing and sulfate-reducing bacteria in Georgia salt marshes, USA

Rolando, J. L.; Kolton, M.; Song, T.; Kostka, J. E.

10.1101/2021.07.06.451362 — microbiology — Posted on 2021-07-07

3253 ZomB is essential for chemotaxis of Vibrio alginolyticus by the rotational direction control of the polar flagellar motor

Takekawa, N.; Nishikino, T.; Hori, K.; Kojima, S.; Homma, M.

10.1101/2021.07.06.451403 — microbiology — Posted on 2021-07-07

3254 Direct Observation of Electrically Conductive Pili Emanating from Geobacter sulfurreducens

Liu, X.; Walker, D. J. F.; Nonnenmann, S.; Sun, D.; Lovley, D. R.

10.1101/2021.07.06.451359 — microbiology — Posted on 2021-07-07

3255 Vibrio cholerae motility in aquatic and mucus-mimicking environments

Grognot, M.; Mittal, A.; Mah'moud, M. A.; Taute, K. M.

10.1101/2021.07.06.451398 — microbiology — Posted on 2021-07-07

3256 Sex-dependent Lupus Ruminococcus blautia gnavus strain induction of zonulin-mediated intestinal permeability and autoimmunity

Deng, J.; Azzouz, D. F.; Ferstler, N.; Silverman, G. J.

10.1101/2021.07.06.451365 — microbiology — Posted on 2021-07-07

3257 A Newcastle disease virus-vector expressing a prefusion-stabilized spike protein of SARS-CoV-2 induces protective immune responses against prototype virus and variants of concern in mice and hamsters

Sun, W.; Liu, Y.; Amanat, F.; Gonzalez-Dominguez, I.; McCroskery, S.; Slamanig, S.; Coughlan, L.; Rosado, V.; Lemus, N.; Jangra, S.; Rathnasinghe, R.; Schotsaert, M.; Martinez, J.; Sano, K.; Mena, I.; Innis, B. L.; Wirachwong, P.; Thai, D. H.; Oliveira, R. D. N.; Scharf, R.; Hjorth, R.; Raghunandan, R.; Krammer, F.; Garcia-Sastre, A.; Palese, P.

10.1101/2021.07.06.451301 — immunology — Posted on 2021-07-07

3258 Nonclinical Safety and Immunogenicity of an rVSV-ΔG-SARS-CoV-2-S vaccine in mice, hamsters, rabbits and pigs

Madar-Balakirski, N.; Rosner, A.; Melamed, S.; Politi, B.; Steiner, M.; Tamir, H.; Yahalom Ronen, Y.; Bar-David, E.; Ben-Shmuel, A.; Sittner, A.; Glinert, I.; Weiss, S.; Bar-Haim, E.; Cohen, H.; Elia, U.; Achdout, H.; Erez, N.; Rotem, S.; Lazar, S.; Nyska, A.; Yitzhaki, S.; Beth-Din, A.; Levy, H.; Paran, N.; Israely, T.; Marcus, H.

10.1101/2021.07.06.451119 — pharmacology and toxicology — Posted on 2021-07-07

3259 Annotating precision for integrative structural models using deep learning

Kasukurthi, N.; Viswanath, S.

10.1101/2021.06.22.449385 — bioinformatics — Posted on 2021-07-07

3260 T-CoV: a comprehensive portal of HLA-peptide interactions affected by SARS-CoV-2 mutations

Nersisyan, S.; Zhiyanov, A.; Shkurnikov, M.; Tonevitsky, A.

10.1101/2021.07.06.451227 — bioinformatics — Posted on 2021-07-07

3261 SARS-CoV-2 genome sequencing with Oxford Nanopore Technology and Rapid PCR Barcoding in Bolivia

Rollano-Penaloza, O. M.; Delgado, C.; Vasquez, A.

10.1101/2021.07.06.451357 — genomics — Posted on 2021-07-07

3262 Mouse Antibodies with Activity Against the SARS-CoV-2 D614G and B.1.351 Variants

Troitskaya, L.; Chan, N. L. S.; Frank, B.; Capon, D.; Zabel, B. A.; Ge, X.; Luo, D.; Martinelli, R.; Jin, J.; Simmons, G.

10.1101/2021.07.05.451203 — molecular biology — Posted on 2021-07-07

3263 mDrop-seq: Massively parallel single-cell RNA-seq of Saccharomyces cerevisiae and Candida albicans

Dohn, R.; Xie, B.; Back, R.; Selewa, A.; Eckart, H.; Rao, R. P.; Basu, A.

10.1101/2021.07.06.451338 — genomics — Posted on 2021-07-07

3264 Micronutrient supplements with iron promote disruptive protozoan and fungal communities in the developing infant gut

Popovic, A.; Bourdon, C.; Wang, P. W.; Guttman, D. S.; Soofi, S.; Bhutta, Z. A.; Bandsma, R. H. J.; Parkinson, J.; Pell, L. G.

10.1101/2021.07.06.451346 — microbiology — Posted on 2021-07-06

3265 Measuring thermodynamic preferences to form non-native conformations in nucleic acids using melting experiments reveals a rich sequence-specific DNA conformational landscape

Rangadurai, A.; Shi, H.; Xu, Y.; Liu, B.; Abou Assi, H.; Boom, J. D.; Zhou, H.; Kimsey, I. J.; Al-Hashimi, H. M.

10.1101/2020.12.26.424438 — biophysics — Posted on 2021-07-06

3266 Zeb2 DNA-binding sites in ES cell derived neuroprogenitor cells reveal autoregulation and align with neurodevelopmental knockout mouse and disease phenotypes.

Birkhoff, J. C.; Korporaal, A. L.; Brouwer, R. W. W.; Milazzo, C.; Mouratidou, L.; van den Hout, M. C. G. N.; van IJcken, W. F. J.; Huylebroeck, D.; Conidi, A.

10.1101/2021.07.06.451350 — cell biology — Posted on 2021-07-06

3267 Multiparametric profiling of cellular lipid metabolism in hypercholesterolemia

Pfisterer, S. G.; Brock, I.; Kanerva, K.; Hlushchenko, I.; Paavolainen, L.; Ripatti, P.; Islam, M. M.; Kyttala, A.; Di Taranto, M. D.; di Frega, A. S.; Fortunato, G.; Kuusisto, J.; Horvath, P.; Ripatti, S.; Laakso, M.; Ikonen, E.

10.1101/2021.04.19.440471 — cell biology — Posted on 2021-07-06

3268 Human Papillomavirus Type 16 E6 induces cell competition

Brimer, N.; Vande Pol, S.

10.1101/2021.07.06.451240 — microbiology — Posted on 2021-07-06

3269 Inhibition of Ras1-MAPK pathways for hypha formation by novel drug candidates in Candida albicans

Park, Y. K.; Shin, J.; Lee, H.-Y.; Kim, H. D.; Kim, J.

10.1101/2021.07.06.451239 — microbiology — Posted on 2021-07-06

3270 Outer membrane vesicles derived from Klebsiella pneumoniae are a driving force for horizontal gene transfer

Dell'Annunziata, F.; DellAversana, C.; Doti, N.; Donadio, G.; Dal Piaz, F.; Izzo, V.; De Filippis, A.; Galdiero, M.; Altucci, L.; Boccia, G.; Galdiero, M.; Folliero, V.; Franci, G.

10.1101/2021.07.06.451238 — microbiology — Posted on 2021-07-06

3271 Social experience alters oxytocinergic modulation in the nucleus accumbens of female prairie voles

Borie, A. M.; Agezo, S.; Lunsford, P.; Boender, A. J.; Guo, J.-D.; Zhu, H.; Berman, G. J.; Young, L. J.; Liu, R. C.

10.1101/2021.07.06.451323 — neuroscience — Posted on 2021-07-06

3272 Ring-shaped multimeric structure enables the acceleration of KaiB-KaiC complex formation induced by the ADP/ATP exchange inhibition

Koda, S.-i.; Saito, S.

10.1101/2021.07.06.451233 — biophysics — Posted on 2021-07-06

3273 EnZymClass: Substrate specificity prediction tool of plant acyl-ACP thioesterases based on Ensemble Learning

Banerjee, D.; Jindra, M. A.; Linot, A. J.; Pfleger, B. F.; Maranas, C. D.

10.1101/2021.07.06.451235 — bioinformatics — Posted on 2021-07-06

3274 Fast and flexible processing of large FRET image stacks using the FRET-IBRA toolkit

Munglani, G.; Vogler, H.; Grossniklaus, U.

10.1101/2021.07.06.451234 — bioinformatics — Posted on 2021-07-06

3275 Selection-Enriched Genomic Loci (SEGL) Reveals Genetic Loci for Environmental Adaptation and Photosynthetic Productivity in Chlamydomonas reinhardtii.

Lucker, B. F.; Panchy, N.; Temple, J.; Benning, U.; Bibik, J.; Neofotis, P.; Weissman, J.; Baxter, I.; Shu, S.-H.; Kramer, D.

10.1101/2021.07.06.451237 — evolutionary biology — Posted on 2021-07-06

3276 Do pesticide residues have enduring negative effect on macroinvertebrates and vertebrates in fallow rice paddies?

Song, J.-S.; Kuo, C.-C.

10.1101/2021.07.06.451252 — ecology — Posted on 2021-07-06

3277 PECAn, a pipeline for image processing and statistical analysis of complex mosaic 3D tissues

Baumgartner, M. E.; Langton, P. F.; Mastrogiannopoulos, A.; Logeay, R.; Piddini, E.

10.1101/2021.07.06.451317 — cell biology — Posted on 2021-07-06

3278 Interrogation of genome-wide, experimentally dissected gene regulatory networks reveals mechanisms underlying dynamic cellular state control

Tan, X.; Worley, J.; Turunen, M.; Wong, K.; Fernandez, E. C.; Paull, E.; Jones, S.; Wang, J.; Noh, H.; Salvatori, B.; Chavez, A.; Califano, A.

10.1101/2021.06.28.449297 — systems biology — Posted on 2021-07-06

3279 Identification of genetic markers and wood properties that predict wood biorefinery potential in aspen bioenergy feedstock (Populus tremula).

Escamez, S.; Luomaranta, M.; Mahler, N.; Gandla, M. L.; Robinson, K. M.; Yassin, Z.; Grahn, T.; Scheepers, G.; Stener, L.-G.; Jonsson, L. J.; Jansson, S.; Street, N.; Tuominen, H.

10.1101/2021.07.06.450716 — plant biology — Posted on 2021-07-06

3280 DeepDDS: deep graph neural network with attention mechanism to predict synergistic drug combinations

Wang, J.; Liu, X.; Shen, S.; Deng, L.; Liu, H.

10.1101/2021.04.06.438723 — bioinformatics — Posted on 2021-07-06

3281 A native mass spectrometry-based assay for rapid assessment of the empty/full capsid ratio in AAV gene therapy products

Strasser, L.; Morgan, T. E.; Guapo, F.; Fuessl, F.; Forsey, D.; Anderson, I.; Bones, J.

10.1101/2021.07.06.451264 — biochemistry — Posted on 2021-07-06

3282 Swarm-mediated phage transport disrupts a biofilm inherently protected from phage penetration

Ratheesh, N. K.; Calderon, C. A.; Zdimal, A. M.; Shrivastava, A.

10.1101/2021.06.25.449910 — microbiology — Posted on 2021-07-06

3283 Global evolutionary dynamics and resistome analysis of Clostridioides difficile ribotype 017

Imwattana, K.; Putsathit, P.; Collins, D. A.; Leepattarakit, T.; Kiratisin, P.; Riley, T. V.; Knight, D. R.

10.1101/2021.07.04.451084 — microbiology — Posted on 2021-07-06

3284 Activity dependent translation in astrocytes dynamically alters the proteome of the perisynaptic astrocyte process

Sapkota, D.; Kater, M. S. J.; Sakers, K.; Nygaard, K. R.; Liu, Y.; Lake, A. M.; Khazanchi, R.; Khankan, R. R.; Smit, A. B.; Maloney, S. E.; Verheijen, M. H. G.; Zhang, Y.; Dougherty, J. D.

10.1101/2020.04.08.033027 — neuroscience — Posted on 2021-07-06

3285 Woman Authorship in Pre-print Versus Peer-Reviewed Oral Health-Related Publications: A Two-Year Observational Study

Rajendran, L.; Khandelwal, N.; Feine, J.; Ioannidou, E.

10.1101/2021.06.25.449988 — scientific communication and education — Posted on 2021-07-06

3286 Injury-Free In Vivo Delivery and Engraftment into the Cornea Endothelium Using Extracellular Matrix Shrink-Wrapped Cells

Palchesko, R. N.; Du, Y.; Geary, M.; Carrasquilla, S.; Shiwarski, D. J.; Khandaker, I.; Feunderburgh, J. L.; Feinberg, A. W.

10.1101/2021.03.01.433476 — bioengineering — Posted on 2021-07-06

3287 Neural ADMIXTURE: rapid population clustering with autoencoders

Mantes, A. D.; Montserrat, D. M.; Bustamante, C.; Giro-i-Nieto, X.; Ioannidis, A. G.

10.1101/2021.06.27.450081 — genomics — Posted on 2021-07-06

3288 Comparative Analysis of non-coding small-RNAs in Pseudomonas aeruginosa Keratitis Strains with Different Antibiotic Susceptibility

Kandasamy, K.; Lalitha, P.; Devarajan, B.

10.1101/2021.07.02.450871 — genomics — Posted on 2021-07-06

3289 Genetic mapping of sex and self-incompatibility determinants in the androdioecious plant Phillyrea angustifolia

Carre, A.; Gallina, S.; Santoni, S.; Vernet, P.; Gode, C.; Castric, V.; Saumitou-Laprade, P.

10.1101/2021.04.15.439943 — evolutionary biology — Posted on 2021-07-06

3290 Polygenic routes lead to parallel altitudinal adaptation in Heliosperma pusillum (Caryophyllaceae)

Szukala, A.; Lovegrove-Walsh, J.; Luqman, H.; Fior, S.; Wolfe, T. M.; Frajman, B.; Schoenswetter, P.; Paun, O.

10.1101/2021.07.05.451094 — evolutionary biology — Posted on 2021-07-06

3291 Cumulative growth and stress responses to the 2018-2019 drought in a European floodplain forest

Schnabel, F.; Purrucker, S.; Schmitt, L.; Engelmann, R. A.; Kahl, A.; Richter, R.; Seele-Dilbat, C.; Skiadaresis, G.; Wirth, C.

10.1101/2021.03.05.434090 — ecology — Posted on 2021-07-06

3292 A local insulin reservoir ensures developmental progression in condition of nutrient shortage in Drosophila

Ghosh, S.; Leng, W.; Wilsch-Brauninger, M.; Leopold, P.; Eaton, S.

10.1101/2021.07.05.451134 — developmental biology — Posted on 2021-07-06

3293 The total mRNA concentration buffering system in yeast is global rather than gene-specific

Garcia-Martinez, J.; Medina, D. A.; Bellvis, P.; Sun, M.; Cramer, P.; Chavez, S.; Perez-Ortin, J. E.

10.1101/2021.01.14.426689 — molecular biology — Posted on 2021-07-06

3294 The determinants of the subjective perception of sleep: insights from a high-density EEG study with serial awakenings

Stephan, A. M.; Lecci, S.; Cataldi, J.; Siclari, F.

10.1101/2021.04.06.438682 — neuroscience — Posted on 2021-07-06

3295 Region-specific, maladaptive, gray matter myelination is associated with differential susceptibility to stress-induced behavior in rats and humans

Long, K. L. P.; Chao, L. L.; Kazama, Y.; An, A.; Hu, K. Y.; Peretz, L.; Muller, D. C. Y.; Roan, V. D.; Misra, R.; Toth, C. E.; Breton, J. M.; Casazza, W.; Mostafavi, S. M.; Huber, B. R.; Woodward, S. H.; Neylan, T. C.; Kaufer, D.

10.1101/2021.02.15.431176 — neuroscience — Posted on 2021-07-06

3296 First detection of herpesvirus and prevalence of mycoplasma infection in free-ranging Hermann s tortoises (Testudo hermanni), and in potential pet vectors

Ballouard, J.-m.; Bonnet, X.; Jourdan, J.; Martinez-Silvestre, A.; Gagno, S.; Fertard, B.; Caron, S.

10.1101/2021.01.22.427726 — zoology — Posted on 2021-07-06

3297 Two different cell-cycle processes determine the timing of cell division in Escherichia coli

Colin, A.; Micali, G.; Faure, L.; Cosentino Lagomarsino, M.; van Teeffelen, S.

10.1101/2021.03.08.434443 — systems biology — Posted on 2021-07-06

3298 Low intrinsic efficacy alone cannot explain the improved side effect profiles of new opioid agonists

Stahl, E. L.; Bohn, L. M.

10.1101/2020.11.19.390518 — pharmacology and toxicology — Posted on 2021-07-06

3299 A computational model for investigating the evolution of colonic crypts during Lynch syndrome carcinogenesis

Haupt, S.; Gleim, N.; Ahadova, A.; Bläker, H.; von Knebel Doeberitz, M.; Kloor, M.; Heuveline, V.

10.1101/2020.12.29.424555 — cancer biology — Posted on 2021-07-06

3300 Antibody structure prediction using interpretable deep learning

Ruffolo, J. A.; Sulam, J.; Gray, J. J.

10.1101/2021.05.27.445982 — biophysics — Posted on 2021-07-06

3301 GIP: An open-source computational pipeline for mapping genomic instability from protists to cancer cells

Spaeth, G. F.; Bussotti, G.

10.1101/2021.06.15.448580 — bioinformatics — Posted on 2021-07-06

3302 DeLUCS: Deep Learning for Unsupervised Clustering of DNA Sequences

Millan Arias, P.; Alipour, F.; Hill, K.; Kari, L.

10.1101/2021.05.13.444008 — bioinformatics — Posted on 2021-07-06

3303 homeRNA: A self-sampling kit for the collection of peripheral blood and stabilization of RNA

Haack, A. J.; Lim, F. Y.; Kennedy, D. S.; Day, J. H.; Adams, K. N.; Lee, J. J.; Berthier, E.; Theberge, A. B.

10.1101/2021.02.08.430337 — bioengineering — Posted on 2021-07-06

3304 Parental population range expansion before secondary contact promotes heterosis

MacPherson, A.; Wang, S.; Yamaguchi, R.; Reiseberg, L.; Otto, S.

10.1101/2020.04.28.066308 — evolutionary biology — Posted on 2021-07-06

3305 An Evolutionary Process Without Variation and Selection

Gabora, L.; Steel, M.

10.1101/2020.08.30.274407 — evolutionary biology — Posted on 2021-07-06

3306 Temperature Increase Drives Critical Slowing Down of Fish Ecosystems

Li, J.; Convertino, M.

10.1101/2021.01.18.427097 — ecology — Posted on 2021-07-06

3307 Quantitative intracellular retention of delivered RNAs through optimized cell fixation and immuno-staining

Paramasivam, P.; Stoter, M.; Corradi, E.; Costa, I. D.; Hoijer, A.; Bartesaghi, S.; Sabirsh, A.; Lindfors, L.; Arteta, M. Y.; Nordberg, P.; Andersson, S.; Baudet, M.-L.; Bickle, M.; Zerial, M.

10.1101/2021.07.06.451306 — cell biology — Posted on 2021-07-06

3308 Age-related demethylation of the TDP-43 autoregulatory region in the human motor cortex

Koike, Y.; Sugai, A.; Hara, N.; Ito, J.; Yokoseki, A.; Ishihara, T.; Yamagishi, T.; Tsuboguchi, S.; Tada, M.; Ikeuchi, T.; Kakita, A.; Onodera, O.

10.1101/2021.01.13.426599 — molecular biology — Posted on 2021-07-06

3309 Pulling the strings of cell cycle: a non-coding RNA, CcnA, modulates the master regulators CtrA and GcrA in Caulobacter crescentus

Beroual, W.; Lalaouna, D.; Benzaina, N.; Valette, O.; Prevost, K.; Denis, Y.; Djendli, M.; Brasseur, G.; Brilli, M.; Robledo, M.; Jimenez Zurdo, J. I.; Masse, E.; Biondi, E. G.

10.1101/756452 — microbiology — Posted on 2021-07-06

3310 Cerebral laterality for writing in right- and left-handers: A functional transcranial Doppler ultrasound study

Papadatou-Pastou, M.; Sampanis, P.; Koumzis, I.; Stefanopoulou, S.; Sousani, D.; Tsigkou, A.; Badcock, N. A.

10.1101/2020.07.14.203588 — neuroscience — Posted on 2021-07-06

3311 Constitutive gene expression differs in three brain regions important for cognition in neophobic and non-neophobic house sparrows (Passer domesticus)

Lattin, C. R.; Kelly, T. R.; Johnson, K. M.; Kelly, M. W.

10.1101/2021.07.06.451290 — animal behavior and cognition — Posted on 2021-07-06

3312 CatSper mediates the chemotactic behavior and motility of the ascidian sperm

Kijima, T.; Kurokawa, D.; Sasakura, Y.; Ogasawara, M.; Aratake, S.; Yoshida, K.; Yoshida, M.

10.1101/2021.07.06.451356 — developmental biology — Posted on 2021-07-06

3313 Cdt1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis

Ratnayeke, N.; Chung, M.; Meyer, T.

10.1101/2021.07.06.451311 — cell biology — Posted on 2021-07-06

3314 Gut-derived metabolites influence neurodevelopmental gene expression and Wnt signalling events in a germ-free zebrafish model

Rea, V.; Bell, I.; Van Raay, T. J.

10.1101/2021.07.06.451297 — molecular biology — Posted on 2021-07-06

3315 SARS-CoV-2 Nsp14 mediates the effects of viral infection on the host cell transcriptome

Zaffagni, M.; Harris, J. M.; Patop, I. L.; Pamudurti, N. R.; Nguyen, S.; Kadener, S.

10.1101/2021.07.02.450964 — molecular biology — Posted on 2021-07-06

3316 Development of Kaptive databases for Vibrio parahaemolyticus O- and K-antigen serotyping

van der Graaf - van Bloois, L.; Chen, H.; Wagenaar, J. A.; Zomer, A. L.

10.1101/2021.07.06.451262 — microbiology — Posted on 2021-07-06

3317 Life on leaves : uncovering temporal dynamics in Arabidopsis' leaf microbiota

Almario, J.; Mahmoudi, M.; Kroll, S.; Agler, M.; Placzek, A.; Mari, A.; Kemen, E. T.

10.1101/2021.07.06.450897 — microbiology — Posted on 2021-07-06

3318 Light-dependent synthesis of a nucleotide second messenger controls bacterial motility

Xu, J.; Koizumi, N.; Morimoto, Y. V.; Ozuru, R.; Masuzawa, T.; Nakamura, S.

10.1101/2021.07.06.451194 — microbiology — Posted on 2021-07-06

3319 Dietary Exposure to Antibiotic Residues Facilitates Metabolic Disorder by Altering the Gut Microbiota and Bile Acid Composition

Chen, R.-A.; Wu, W.-K.; Panyod, S.; Liu, P.-Y.; Chuang, H.-L.; Chen, Y.-H.; Lyu, Q.; Hsu, H.-C.; Lin, T.-L.; Shen, T.-C. D.; Yang, Y.-T.; Zou, H.-B.; Huang, H.-S.; Lin, Y.-E.; Chen, C.-C.; Ho, C.-T.; Lai, H.-C.; Wu, M.-S.; Hsu, C.-C.; Sheen, L.-Y.

10.1101/2021.07.06.451284 — microbiology — Posted on 2021-07-06

3320 The fruit fly Anastrepha obliqua harbors three kingdoms of life in its intestinal tract.

Amores, G. R.; Zepeda-Ramos, G.; Garcia-Fajardo, L. V.; Hernandez, E.; Guillen-Navarro, K.

10.1101/2021.07.06.451314 — microbiology — Posted on 2021-07-06

3321 Ca2+-dependent liquid-liquid phase separation underlies intracellular Ca2+ stores.

Mayfield, J. E.; Pollak, A. J.; Worby, C. A.; Xu, J. C.; Tandon, V.; Newton, A. C.; Dixon, J. E.

10.1101/2021.07.06.451223 — biochemistry — Posted on 2021-07-06

3322 Structure of mycobacterial CIII2CIV2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203)

Yanofsky, D. J.; Di Trani, J. M.; Krol, S.; Abdelaziz, R.; Bueler, S. A.; Imming, P.; Brzezinski, P.; Rubinstein, J. L.

10.1101/2021.07.06.451285 — biochemistry — Posted on 2021-07-06

3323 C2CD6 is required for assembly of the CatSper calcium channel complex and fertilization

Yang, F.; Gervasi, M. G.; Leu, N. A.; Tourzani, D. A.; Ruthel, G.; Visconti, P. E.; Wang, J.

10.1101/2021.07.06.451342 — developmental biology — Posted on 2021-07-06

3324 Downregulation of WT1 transcription factor gene expression is required to promote myocardial fate

Marques, I. J.; Ernst, A.; Arora, P.; Vianin, A.; Hetke, T.; Sanz-Morejon, A.; Naumann, U.; Odriozola, A.; Oliva, X. L.; Andres-Delgado, L.; Haberthuer, D.; Zuber, B.; Torroja, C.; Hlushchuk, R.; Osterwalder, M.; Simoes, F.; Englert, C.; Mercader, N.

10.1101/2021.07.06.451274 — developmental biology — Posted on 2021-07-06

3325 Characterization of the Drosophila adult hematopoietic system reveals a rare cell population with differentiation and proliferation potential.

Boulet, M.; Renaud, Y.; Lapraz, F.; Benmimoun, B.; Vandel, L.; Waltzer, L.

10.1101/2021.07.06.451161 — developmental biology — Posted on 2021-07-06

3326 Perfluorononanoic acid impedes mouse oocyte maturation by inducing mitochondrial dysfunction and oxidative stress

Jiao, X.; Liu, N.; Xu, Y.; Qiao, H.

10.1101/2021.07.06.451300 — cell biology — Posted on 2021-07-06

3327 Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates

Liu, X.-M.; Ma, L.; Schekman, R.

10.1101/2021.07.06.451310 — cell biology — Posted on 2021-07-06

3328 TAF8 regions important for TFIID lobe B assembly, or for TAF2 interactions, are required for embryonic stem cell survival

Scheer, E.; Luo, J.; Ruffenach, F.; Garnier, J.-M.; Kolb-Cheynel, I.; Gupta, K.; Berger, I.; Ranish, J.; Tora, L.

10.1101/2021.07.06.451281 — molecular biology — Posted on 2021-07-06

3329 Isoform resolved measurements of absolute translational efficiency define interplay of HIF and mTOR dysregulation in kidney cancer

Sugimoto, Y.; Ratcliffe, P. J.

10.1101/2021.07.06.451052 — molecular biology — Posted on 2021-07-06

3330 Chasing the metabolism of novel syntrophic acetate-oxidizing bacteria in thermophilic methanogenic chemostats

Zeng, Y.; Zheng, D.; Gou, M.; Xia, Y. Z.; Chen, Y.-T.; Nobu, M. K.; Tang, Y.-Q.

10.1101/2021.07.06.451242 — microbiology — Posted on 2021-07-06

3331 Impairment of a cyanobacterial glycosyltransferase that modifies a pilin results in biofilm development

Suban, S.; Schwarz, R.; Sendersky, E.; Golden, S. S.

10.1101/2021.07.06.449578 — microbiology — Posted on 2021-07-06

3332 MiDAS 4: A global catalogue of full-length 16S rRNA gene sequences and taxonomy for studies of bacterial communities in wastewater treatment plants

Dueholm, M. S.; Nierychlo, M.; Andersen, K. S.; Joergensen, V. R.; Knutsson, S.; the MiDAS Global Consortium, ; Albertsen, M.; Nielsen, P. H.

10.1101/2021.07.06.451231 — microbiology — Posted on 2021-07-06

3333 CCAR-1 has a novel role in regulating the Caenorhabditis elegans germline

Westerheide, S. D.; Lugano, D. I.; Deonarine, A.; Park, M. A.

10.1101/2021.07.06.451293 — genomics — Posted on 2021-07-06

3334 A polygenic architecture with conditionally neutral effects underlies ecological differentiation in Silene

Gramlich, S.; Liu, X.; Favre, A.; Buerkle, C. A.; Karrenberg, S.

10.1101/2021.07.06.451304 — evolutionary biology — Posted on 2021-07-06

3335 Managing human mediated range shifts: understanding spatial, temporal and genetic variation in marine non- native species

Holman, L. E.; Parker-Nance, S.; de Bruyn, M.; Creer, S.; Carvalho, G.; Rius, M.

10.1101/2021.07.06.451303 — ecology — Posted on 2021-07-06

3336 Small molecules enhance the potency of natural antimicrobial peptides

Losasso, V.; Agarwal, K.; Waskar, M.; Majumdar, A.; Crain, J.; Winn, M.; Hoptroff, M.

10.1101/2021.07.06.451332 — molecular biology — Posted on 2021-07-06

3337 Multidimensional MRI for characterization of subtle axonal injury accelerated using an adaptive nonlocal multispectral filter

Benjamini, D.; Bouhrara, M.; Komlosh, M. E.; Iacono, D.; Perl, D. P.; Brody, D. L.; Basser, P.

10.1101/2021.07.06.451291 — neuroscience — Posted on 2021-07-06

3338 Glial place cells: complementary encoding of spatial information in hippocampal astrocytes

Curreli, S.; Bonato, J.; Romanzi, S.; Panzeri, S.; Fellin, T.

10.1101/2021.07.06.451296 — neuroscience — Posted on 2021-07-06

3339 The Phytochemical Diversity of Commercial Cannabis in the United States

Smith, C. J.; Vergara, D.; Keegan, B.; Jikomes, N.

10.1101/2021.07.05.451212 — plant biology — Posted on 2021-07-06

3340 Algorithms for discovery of cis-eQTL signals in woody species: the vine (Vitis vinifera L.) as a study model

Martinez-Garcia, P. J.; Mas-Gomez, J.; Wegrzyn, J. L.; Botia, J. A.

10.1101/2021.07.06.450811 — plant biology — Posted on 2021-07-06

3341 The molecular mechanism of cytoadherence to placenta or tumor cells through VAR2CSA from Plasmodium falciparum

Wang, W.; Wang, Z.; Yang, X.; Gao, Y.; Zhang, X.; Cao, L.; Dai, A.; Sun, J.; Sun, L.; Jiang, L.; Chen, Z.; Wang, L.

10.1101/2021.07.06.451098 — biophysics — Posted on 2021-07-06

3342 Molecular mechanism of target site selection and remodeling by type V CRISPR-associated transposons

Querques, I.; Schmitz, M.; Oberli, S.; Chanez, C.; Jinek, M.

10.1101/2021.07.06.451292 — biochemistry — Posted on 2021-07-06

3343 Predicting RNA splicing from DNA sequence using Pangolin

Zeng, T.; Li, Y. I.

10.1101/2021.07.06.451243 — genomics — Posted on 2021-07-06

3344 Tumour Suppressor Parafibromin/Hyrax Governs Cell Polarity and Centrosome Assembly in Neural Stem Cells

Deng, Q.; Wang, C.; Koe, C. T.; Heinen, J. P.; Tan, Y. S.; Li, S.; GONZALEZ, C.; Sung, W.-K.; Wang, H.

10.1101/2021.07.06.451232 — developmental biology — Posted on 2021-07-06

3345 Identification of the cell-type-specific ER membrane protein Tanmp expressed in hypothalamic tanycytes and subsets of neurons

Takahashi, O.; Tanahashi, M.; Yokoi, S.; Kaneko, M.; Tokuhara, T.; Yanaka, K.; Nakagawa, S.; Maita, H.

10.1101/2021.07.06.451253 — cell biology — Posted on 2021-07-06

3346 Phosphorylation of STIM1 at ERK/CDK sites is dispensable for cell migration and ER partitioning in mitosis

Hammad, A. S.; Yu, F.; Botheju, W.; Elmi, A. A.; Alcantara-Adap, E.; Machaca, K.

10.1101/2021.07.06.451280 — cell biology — Posted on 2021-07-06

3347 PLK1 controls centriole distal appendage formation and centrobin removal via independent pathways

LeRoux-Bourdieu, M.; Harry, D.; Meraldi, P.

10.1101/2021.07.06.451279 — cell biology — Posted on 2021-07-06

3348 Irisin stimulates the release of CXCL1 from differentiating human subcutaneous and deep-neck derived adipocytes via upregulation of NFκB pathway

Shaw, A.; B. Toth, B.; Kiraly, R.; Arianti, R.; Csomos, I.; Poliska, S.; Vamos, A.; Korponay-Szabo, I. R.; Bacso, Z.; Györy, F.; Fesüs, L.; Kristof, E.

10.1101/2021.07.06.451152 — cell biology — Posted on 2021-07-06

3349 UVC inactivation of pathogenic samples suitable for cryoEM analysis

Depelteau, J. S.; Renault, L.; Althof, N.; Cassidy, C. K.; Mendonca, L. M.; Jensen, G. J.; Resch, G. P.; Briegel, A.

10.1101/2021.07.06.451241 — molecular biology — Posted on 2021-07-06

3350 Daily oscillation of the excitation/inhibition ratio is disrupted in two mouse models of autism

Bridi, M.; Luo, N.; Kim, G.; O'Ferrall, C.; Oatel, R.; Bertrand, S.; Kannan, S.; Kirkwood, A.

10.1101/2021.07.05.451213 — neuroscience — Posted on 2021-07-06

3351 Adolescent dopamine neurons represent reward differently during action and state guided learning

McCane, A.; Wegener, M.; Faraji, M.; Garcia, M. R.; Wallin-Miller, K.; Costa, V.; Moghaddam, B.

10.1101/2021.07.05.451195 — neuroscience — Posted on 2021-07-06

3352 Target-specific control of olfactory bulb periglomerular cells by GABAergic and cholinergic basal forebrain inputs

Desaintjan, D.

10.1101/2021.07.06.451255 — neuroscience — Posted on 2021-07-06

3353 Developmental increase of inhibition drives decorrelation of neural activity

Chini, M.; Pfeffer, T.; Hanganu-Opatz, I. L.

10.1101/2021.07.06.451299 — neuroscience — Posted on 2021-07-06

3354 Discovery of putative Golgi S-Adenosyl methionine transporters reveals the importance of plant cell wall polysaccharide methylation

Temple, H.; Phyo, P.; Yang, W.; Lyczakowski, J. J.; Echevarria-Poza, A.; Yakunin, I.; Parra-Rojas, J. P.; Terrett, O. M.; Saez-Aguayo, S.; Dupree, R.; Orellana, A.; Hong, M.; Dupree, P.

10.1101/2021.07.06.451061 — plant biology — Posted on 2021-07-06

3355 Compound-specific, concentration-independent biophysical properties of sodium channel inhibitor mechanism of action

Pesti, K.; Foldi, M. C.; Zboray, K.; Toth, A. V.; Lukacs, P.; Mike, A.

10.1101/2021.07.05.451191 — pharmacology and toxicology — Posted on 2021-07-06

3356 Projecting genetic associations through gene expression patterns highlights disease etiology and drug mechanisms

Pividori, M.; Lu, S.; Li, B.; Su, C.; Johnson, M. E.; Wei, W.-Q.; Feng, Q.; Namjou, B.; Kiryluk, K.; Kullo, I.; Luo, Y.; Sullivan, B. D.; Skarke, C.; Ritchie, M. D.; Grant, S. F. A.; Greene, C. S.

10.1101/2021.07.05.450786 — bioinformatics — Posted on 2021-07-06

3357 Network-level containment of single-species bioengineering

Maull, V.; Sole, R.

10.1101/2021.07.05.451200 — bioengineering — Posted on 2021-07-06

3358 Population-level inference for home-range areas

Fleming, C. H.; Deznabi, I.; Alavi, S.; Crofoot, M. C.; Hirsch, B. T.; Medici, E. P.; Noonan, M. J.; Kays, R.; Fagan, W. F.; Sheldon, D.; Calabrese, J. M.

10.1101/2021.07.05.451204 — ecology — Posted on 2021-07-06

3359 Disentangling niche theory and beta diversity change

Godsoe, W.; Bellingham, P. J.; Moltchanova, E.

10.1101/2021.07.05.451214 — ecology — Posted on 2021-07-06

3360 Differential impact of Kv8.2 loss on rod and cone signaling and degeneration.

Inamdar, S. M.; Lankford, C. K.; Poria, D.; Laird, J. G.; Solessio, E.; Kefalov, V. J.; Baker, S. A.

10.1101/2021.07.05.451197 — neuroscience — Posted on 2021-07-06

3361 Brain-like functional specialization emerges spontaneously in deep neural networks

Dobs, K.; Martinez, J.; Kell, A. J. E.; Kanwisher, N.

10.1101/2021.07.05.451192 — neuroscience — Posted on 2021-07-06

3362 An advanced automated patch clamp protocol design to investigate drug - ion channel binding dynamics.

Lukacs, P.; Pesti, K.; Foldi, M. C.; Zboray, K.; Toth, A. V.; Papp, G.; Mike, A.

10.1101/2021.07.05.451189 — pharmacology and toxicology — Posted on 2021-07-06

3363 Genetic characterization of outbred Sprague Dawley rats and utility for genome-wide association studies

Gileta, A. F.; Fitzpatrick, C. J.; Chitre, A. S.; St. Pierre, C. L.; Joyce, E. V.; Maguire, R. J.; McLeod, A. M.; Gonzales, N. M.; Williams, A. E.; Morrow, J. D.; Robinson, T. E.; Flagel, S. B.; Palmer, A. A.

10.1101/412924 — genetics — Posted on 2021-07-06

3364 Exploring the Inner Workings of Neuron Circuits That Exhibit Persistent Activity To Explain How Working Memory and Executive Function Are Implemented in The Brain

Gomez, P.

10.1101/2021.07.05.451167 — neuroscience — Posted on 2021-07-06

3365 Relaxation time asymmetry in stator dynamics of the bacterial flagellar motor

Perez-Carrasco, R.; Franco-Onate, M.-J.; Walter, J.-C.; Dorignac, J.; Geniet, F.; Palmeri, J.; Parmeggiani, A.; Walliser, N.-O.; Nord, A. L.

10.1101/2021.07.05.451114 — biophysics — Posted on 2021-07-06

3366 CRISPR-VAE: A Method for Explaining CRISPR/Cas12a Predictions, and an Efficiency-aware gRNA Sequence Generator

Obeid, A. S.; Al Marzouqi, H.

10.1101/2021.07.05.451176 — bioinformatics — Posted on 2021-07-06

3367 Mapping the glycosyltransferase fold landscape using deep learning

Taujale, R.; Zhou, Z.; Yeung, W.; Moremen, K. W.; Li, S.; Kannan, N.

10.1101/2021.07.05.451183 — bioinformatics — Posted on 2021-07-06

3368 The crucial role of genome-wide genetic variation in conservation

Kardos, M.; Armstrong, E.; Fitzpatrick, S. W.; Hauser, S.; Hedrick, P.; Miller, J.; Tallmon, D.; Funk, W. C.

10.1101/2021.07.05.451163 — evolutionary biology — Posted on 2021-07-06

3369 Message in a Bottle, Metabarcoding Enables Biodiversity Comparisons Across Ecoregions

Steinke, D.; deWaard, S. L.; Sones, J. E.; Ivanova, N. V.; Prosser, S. W.; Perez, K.; Braukmann, T. W. A.; Milton, M.; Zakharov, E.; deWaard, J. R.; Ratnasingham, S.; Hebert, P. D. N.

10.1101/2021.07.05.451165 — ecology — Posted on 2021-07-06

3370 Find me if you can: Pre- and Post-hurricane Densities of the Red-bellied Racer (Alsophis rufiventris) on St. Eustatius, and a review of the genus in the Caribbean

Madden, H.; Fernandez, D. S.; Tremblay, R. L.; Verdel, K.; Kaboord, B.

10.1101/2021.07.05.451169 — ecology — Posted on 2021-07-06

3371 Skill and value in recruitment forecasting

Kiaer, C.; Neuenfeldt, S.; Payne, M. R.

10.1101/2021.07.05.451182 — ecology — Posted on 2021-07-06

3372 Transcriptional heterogeneity of ventricular zone cells throughout the embryonic mouse forebrain

Lee, D. R.; Rhodes, C.; Mitra, A.; Zhang, Y.; Maric, D.; Dale, R. K.; Petros, T. J.

10.1101/2021.07.05.451224 — neuroscience — Posted on 2021-07-06

3373 Discrete Roles of the Ir76b Ionotropic Co-Receptor Impact Olfaction, Blood Feeding, and Mating in the Malaria Vector Mosquito Anopheles coluzzii

Ye, Z.; Liu, F.; Sun, H.; Baker, A. P.; Zwiebel, L.

10.1101/2021.07.05.451160 — neuroscience — Posted on 2021-07-06

3374 Inhibitory control of synaptic signals preceding motor action in mouse frontal cortex

Zhang, C.; Koukouli, F.; Allegra, M.; Ortiz, C.; Kao, H.-L.; Maskos, U.; Changeux, J.-P.; Schmidt-Hieber, C.

10.1101/2021.07.05.451151 — neuroscience — Posted on 2021-07-06

3375 Individualized prediction of future cognition using baseline developmental changes in cortical anatomy

Khundrakpam, B.; Booij, L.; Jeon, S.; Tohka, J.; Evans, A. C.

10.1101/2021.07.05.451172 — neuroscience — Posted on 2021-07-06

3376 A Distributed Network for Multimodal Experiential Representation of Concepts

Tong, J.-Q.; Binder, J. R.; Humphries, C. J.; Conant, L. L.; Fernandino, L.

10.1101/2021.07.05.451188 — neuroscience — Posted on 2021-07-06

3377 Genome sequences of the five Sitopsis species of Aegilops and the origin of polyploid wheat B-subgenome

Li, L.; Zhang, Z.; Wang, Z.; Li, N.; Sha, Y.; Wang, X.; Ding, N.; Li, Y.; Zhao, J.; Wu, Y.; Gong, L.; Mafessoni, F.; Levy, A.; Liu, B.

10.1101/2021.07.05.444401 — evolutionary biology — Posted on 2021-07-06

3378 Adenylate Kinase 2 deficiency causes NAD+ depletion and impaired purine metabolism during myelopoiesis

Wang, W.; DeVilbiss, A.; Arreola, M.; Mathews, T.; Martin-Sandoval, M.; Zhao, Z.; Awani, A.; Dever, D.; Al-Herz, W.; Noratangelo, L.; Porteus, M. H.; Morrison, S. J.; Weinacht, K. G.

10.1101/2021.07.05.450633 — cell biology — Posted on 2021-07-06

3379 Up and to the light: intra- and interspecific variability of photo- and geo-tactic oviposition preferences in genus Trichogramma

Perez, G.; Burte, V.; Ayed, F.; Groussier, G.; van Oudenhove, L.; Mailleret, L.; Calcagno, V.

10.1101/2021.03.30.437671 — ecology — Posted on 2021-07-06

3380 Female meiosis II and pronuclear fusion require Bicaudal-D

Vazquez Pianzola, M. P.; Beuchle, D.; Saro, G.; Hernandez, G.; Maldonado, G.; Brunssen, D.; Meister, P.; Suter, B.

10.1101/2020.12.22.423980 — developmental biology — Posted on 2021-07-06

3381 Pulling the strings of cell cycle: a non-coding RNA, CcnA, modulates the master regulators CtrA and GcrA in Caulobacter crescentus

Beroual, W.; Lalaouna, D.; Benzaina, N.; Valette, O.; Prevost, K.; Denis, Y.; Djendli, M.; Brasseur, G.; Brilli, M.; Robledo, M.; Jimenez Zurdo, J. I.; Masse, E.; Biondi, E. G.

10.1101/756452 — microbiology — Posted on 2021-07-06

3382 Modulation of dLGN firing mode across multiple timescales is predicted by pupil size dynamics

Crombie, D.; Spacek, M. A.; Leibold, C.; Busse, L.

10.1101/2021.04.30.442134 — neuroscience — Posted on 2021-07-06

3383 Lightsheet Optical Tweezer (LOT) for Optical Manipulation of Microscopic Particles and Live Cells

Mondal, P. P.; Singh, A.; Joshi, P.; Basumatary, J.; Baro, N.

10.1101/2021.07.05.451038 — biophysics — Posted on 2021-07-06

3384 A pipeline to detect the relationship between transposable elements and adjacent genes in host genomes

Meguerditchian, C.; Ergun, A.; DECROOCQ, V.; LEFEBVRE, M.; Bui, Q. T.

10.1101/2021.02.25.432867 — bioinformatics — Posted on 2021-07-06

3385 A computationally designed fluorescent biosensor for D-serine

Vongsouthi, V.; Whitfield, J. H.; Unichenko, P.; Mitchell, J. A.; Breithausen, B.; Khersonsky, O.; Kremers, L.; Janovjak, H.; Monai, H.; Hirase, H.; Fleishman, S. J.; Henneberger, C.; Jackson, C. J.

10.1101/2020.08.18.255380 — biochemistry — Posted on 2021-07-06

3386 A Kozak-related non-coding deletion effectively increases B.1.1.7 transmissibility

Yang, J.; Zhang, G.; Yu, D.; Cao, R.; Wu, X.; Ling, Y.; Pan, Y.-H.; Yi, C.; Sun, X.; Sun, B.; Zhang, Y.; Zhao, G.-P.; Li, Y.; Li, H.

10.1101/2021.04.30.442029 — evolutionary biology — Posted on 2021-07-06

3387 Genetic mapping of sex and self-incompatibility determinants in the androdioecious plant Phillyrea angustifolia

Carre, A.; Gallina, S.; Santoni, S.; Vernet, P.; Gode, C.; Castric, V.; Saumitou-Laprade, P.

10.1101/2021.04.15.439943 — evolutionary biology — Posted on 2021-07-06

3388 All-trans retinoic acid induces synaptopodin-dependent metaplasticity in mouse dentate granule cells

Lenz, M.; Eichler, A.; Kruse, P.; Muellerleile, J.; Deller, T.; Jedlicka, P.; Vlachos, A.

10.1101/2021.07.05.451170 — neuroscience — Posted on 2021-07-06

3389 Simultaneous pure T2 and varying T2'-weighted BOLD fMRI using Echo Planar Time-resolved Imaging for mapping cortical-depth dependent responses

Wang, F.; Dong, Z.; Wald, L. L.; Polimeni, J. R.; Setsompop, K.

10.1101/2021.05.22.445292 — neuroscience — Posted on 2021-07-06

3390 ZETA: a parameter-free statistical test for neuronal responsiveness

Montijn, J. S.; Seignette, K.; Howlett, M. H.; Cazemier, J. L.; Kamermans, M.; Levelt, C. N.; Heimel, J. A.

10.1101/2020.09.24.311118 — neuroscience — Posted on 2021-07-06

3391 Multifunctional RNA-binding proteins influence mRNA abundance and translational efficiency of distinct sets of target genes

Schneider-Lunitz, V.; Ruiz-Orera, J.; Hubner, N.; van Heesch, S.

10.1101/2021.04.13.439465 — systems biology — Posted on 2021-07-06

3392 Variation in mechanical and structural properties of enamel in primate molars

Towle, I.; Loho, T.; Salem, A.; Loch, C.

10.1101/2021.07.05.451217 — evolutionary biology — Posted on 2021-07-06

3393 A local insulin reservoir ensures developmental progression in condition of nutrient shortage in Drosophila

Ghosh, S.; Leng, W.; Wilsch-Brauninger, M.; Leopold, P.; Eaton, S.

10.1101/2021.07.05.451134 — developmental biology — Posted on 2021-07-06

3394 Antisense-mediated repression of SAGA-dependent genes involves the HIR histone chaperone

Soudet, J.; Beyrouthy, N.; Pastucha, A. M.; Maffioletti, A.; Bakir, Z.; Stutz, F.

10.1101/2021.07.05.451174 — molecular biology — Posted on 2021-07-06

3395 Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques

He, W.-t.; Yuan, M.; Callaghan, S.; Musharrafieh, R.; Song, G.; Silva, M.; Beutler, N.; Lee, W.-H.; Yong, P.; Torres, J. L.; Melo, M.; Zhou, P.; Zhao, F.; Zhu, X.; Peng, L.; Huang, D.; Anzanello, F.; Ricketts, J.; Parren, M.; Garcia, E.; Ferguson, M.; Rinaldi, W.; Rawlings, S. A.; Nemazee, D.; Smith, D. M.; Briney, B.; Safonova, Y.; Rogers, T.; Crotty, S.; Irvine, D. J.; Ward, A. B.; Wilson, I. A.; Burton, D. R.; Andrabi, R.

10.1101/2021.07.05.451222 — immunology — Posted on 2021-07-06

3396 The relationship between mucosal microbiota, colitis and systemic inflammation in Chronic Granulomatous Disorder

Davrandi, M.; Harris, S.; Smith, P. J.; Murray, C. D.; Lowe, D. M.

10.1101/2021.07.05.451147 — immunology — Posted on 2021-07-06

3397 Members of the CUGBP Elav-Like Family of RNA-Binding Proteins are Expressed in Distinct Populations of Primary Sensory Neurons

Grlickova-Duzevik, E.; Michael, M.; McGrath-Conwell, A.; Neufeld, P. K.; Reimonn, T. M.; Molliver, D. C.; Harrison, B. J.

10.1101/2021.07.05.451166 — neuroscience — Posted on 2021-07-06

3398 D-cysteine is an endogenous regulator of neural progenitor cell dynamics in the mammalian brain

Semenza, E. R.; Harraz, M. M.; Abramson, E.; Malla, A. P.; Vasavda, C.; Gadalla, M. M.; Kornberg, M. D.; Snyder, S. H.; Roychaudhuri, R.

10.1101/2021.07.05.451211 — neuroscience — Posted on 2021-07-06

3399 Polybasic patches in both C2 domains of Synaptotagmin-1 are required for evoked neurotransmitter release

Wu, Z.; Ma, L.; Courtney, N. A.; Zhu, J.; Zhang, Y.; Chapman, E. R.; Karatekin, E.

10.1101/2021.07.05.451149 — neuroscience — Posted on 2021-07-06

3400 p53-mediated neurodegeneration in the absence of the nuclear protein Akirin2

Peek, S. L.; Bosch, P. J.; Bahl, E.; Iverson, B. J.; Parida, M.; Bais, P.; Manak, J. R.; Michaelson, J.; Burgess, R. W.; Weiner, J. A.

10.1101/2021.07.05.451155 — neuroscience — Posted on 2021-07-06

3401 CALR frameshift mutations in MPN patient-derived iPS cells accelerate maturation of megakaryocytes

Olschok, K.; Han, L.; de Toledo, M. A. S.; Boehnke, J.; Grasshoff, M.; Costa, I. G.; Theocharides, A.; Maurer, A.; Schueler, H. M.; Buhl, E. M.; Pannen, K.; Baumeister, J.; Kalmer, M.; Gupta, S.; Boor, P.; Gezer, D.; Bruemmendorf, T. H.; Zenke, M.; Chatain, N.; Koschmieder, S.

10.1101/2021.07.05.451130 — cancer biology — Posted on 2021-07-05

3402 Single-molecule imaging with cell-derived nanovesicles reveals early binding dynamics at a cyclic nucleotide-gated ion channel

Patel, V. R.; Salinas, A. M.; Qi, D.; Gupta, S.; Sidote, D. J.; Goldschen-Ohm, M. P.

10.1101/2021.07.05.451181 — biophysics — Posted on 2021-07-06

3403 Increased Histone-DNA Complexes and Endothelial-Dependent Thrombin Generation in Severe COVID-19

Bouchard, B. A.; Colovos, C.; Lawson, M.; Sackhiem, A.; Mould, K. J.; Janssen, W. J.; Cohen, M. J.; Majumdar, D.; Freeman, K.

10.1101/2021.07.03.450992 — biochemistry — Posted on 2021-07-05

3404 Feeding effects on liver mitochondrial bioenergetics of Boa constrictor (Serpentes: Boidae)

Araujo, H. R. M.; Sartori, M. R.; Navarro, C. D. C.; de Carvalho, J. E.; Cruz, A. L.

10.1101/2021.07.05.451168 — biochemistry — Posted on 2021-07-05

3405 Protease Resistance of ex vivo Amyloid Fibrils implies the proteolytic Selection of disease-associated Fibril Morphologies

Schoenfelder, J.; Pfeiffer, P. B.; Pradhan, T.; Bijzet, J.; Hazenberg, B. P. C.; Schoenland, S. O.; Hegenbart, U.; Reif, B.; Haupt, C.; Faendrich, M.

10.1101/2021.07.05.451219 — biochemistry — Posted on 2021-07-06

3406 A PKA Inhibitor Motif within Smoothened Controls Hedgehog Signal Transduction

Happ, J. T.; Arveseth, C. D.; Bruystens, J.; Bertinetti, D.; Nelson, I. B.; Olivieri, C.; Hedeen, D. S.; Zhu, J.-F.; Capener, J. L.; Bröckel, J. W.; Vu, L.; King, C. C.; Ruiz-Perez, V. L.; Veglia, G.; Herberg, F. W.; Taylor, S. S.; Myers, B. R.

10.1101/2021.07.05.451193 — biochemistry — Posted on 2021-07-06

3407 Construction of a new chromosome-scale, long-read reference genome assembly of the Syrian hamster, Mesocricetus auratus

Harris, R. A.; Raveendran, M.; Lyfoung, D. T.; Sedlazeck, F. J.; Mahmoud, M.; Prall, T.; Karl, J.; Doddapaneni, H.; Meng, Q.; Han, Y.; Muzny, D.; Wiseman, R. W.; O'Connor, D. H.; Rogers, J.

10.1101/2021.07.05.451071 — genomics — Posted on 2021-07-05

3408 Mutation signatures inform the natural host of SARS-CoV-2

He, X.

10.1101/2021.07.05.451089 — evolutionary biology — Posted on 2021-07-05

3409 Increased frequency of recurrent in-frame deletions in new expanding lineages of SARS CoV-2 reflects immune selective pressure

Alisoltani, A.; Jaroszewski, L.; Iyer, M.; Iranzadeh, A.; Godzik, A.

10.1101/2021.07.04.451027 — evolutionary biology — Posted on 2021-07-06

3410 Exocyst Inactivation in Urothelial Cells Disrupts Autophagy and Activates non-canonical NF-κB

Ortega, M. A.; Villiger, R. K.; Harrison-Chau, M.; Lieu, S.; Tamashiro, K.-K.; Lee, A. J.; Fujimoto, B. A.; Patwardhan, G. Y.; Kepler, J.; Fogelgren, B.

10.1101/2021.07.05.451173 — developmental biology — Posted on 2021-07-05

3411 Mitochondrial dysfunction and oxidative stress contribute to cognitive and motor impairment in FOXP1 syndrome

Wang, J.; Froehlich, H.; Torres, F. B.; Silva, R. L.; Agarwal, A.; Rappold, G. A.

10.1101/2021.07.05.451143 — molecular biology — Posted on 2021-07-05

3412 Optimized nickase- and nuclease-based prime editing in human and mouse cells

Adikusuma, F.; Lushington, C.; Arudkumar, J.; Godahewa, G. I.; Chey, Y. C. J.; Gierus, L.; Piltz, S.; Reti, D.; Wilson, L.; Bauer, D.; Thomas, P.

10.1101/2021.07.01.450810 — molecular biology — Posted on 2021-07-05

3413 Identification of the receptor-binding protein of Clostridium difficile phage CDHS-1 reveals a new class of receptor-binding domains.

Dowah, A. S. A.; Xia, G.; Thanki, A. M.; Ali, A. A. K.; Shan, J.; Wallis, R.; Clokie, M. R. J.

10.1101/2021.07.05.451159 — molecular biology — Posted on 2021-07-05

3414 U2 snRNA structure is influenced by SF3A and SF3B proteins but not by SF3B inhibitors

Urabe, V. K.; Stevers, M.; Ghosh, A. K.; Jurica, M. S.

10.1101/2021.07.05.451154 — molecular biology — Posted on 2021-07-06

3415 Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection

Li, L.; Honda-Okubo, Y.; Huang, Y.; Jang, H.; Carlock, M. A.; Baldwin, J.; Piplani, S.; Bebin-Blackwell, A. G.; Forgacs, D.; Sakamoto, K.; Stella, A.; Turville, S.; Chataway, T.; Colella, A.; Triccas, J.; Ross, T.; Petrovsky, N.

10.1101/2021.07.03.451026 — immunology — Posted on 2021-07-05

3416 Microglia and border-associated mouse macrophages maintain their embryonic origin during Alzheimers disease

Ruedl, c.; Wu, X.; Saito, T.; Saido, t.; Barron, A. M.

10.1101/2021.07.05.451201 — immunology — Posted on 2021-07-05

3417 Predicted Impact of the Viral Mutational Landscape on the Cytotoxic Response against SARS-CoV-2

Foix, A.; Lopez, D.; McConnell, M. J.; Martin-Galiano, A. J.

10.1101/2021.07.04.451040 — immunology — Posted on 2021-07-05

3418 Linguistic modulation of the neural encoding of phonemes

Kim, S.-G.; De Martino, F.; Overath, T.

10.1101/2021.07.05.451175 — neuroscience — Posted on 2021-07-05

3419 Dynamics of SARS-CoV-2 host cell interactions inferred from transcriptome analyses

Adam, L.; Stanifer, M.; Springer, F.; Mathony, J.; Di Ponzio, C.; Eils, R.; Boulant, S.; Niopek, D.; Kallenberger, S. M.

10.1101/2021.07.04.450986 — systems biology — Posted on 2021-07-05

3420 A SARS-CoV-2 nucleocapsid protein TR-FRET assay amenable to high-throughput screening

Gorshkov, K.; Vasquez, D. M.; Chiem, K.; Ye, C.; Nguyen Tran, B.; de la Torre, J. C.; Moran, T.; Chen, C. Z.; Martinez-Sobrido, L.; Zheng, W.

10.1101/2021.07.03.450938 — pharmacology and toxicology — Posted on 2021-07-05

3421 A cGAMP-containing hydrogel for prolonged SARS-CoV-2 RBD subunit vaccine exposure induces a broad and potent humoral response

Gale, E. C.; Lahey, L. J.; Böhnert, V.; Powell, A. E.; Ou, B. S.; Carozza, J. A.; Li, L.; Appel, E.

10.1101/2021.07.03.451025 — bioengineering — Posted on 2021-07-05

3422 Sexually distinct song cultures in a songbird metapopulation

Webb, W. H.; Roper, M. M.; Pawley, M. D.; Fukuzawa, Y.; Harmer, A. M.; Brunton, D. H.

10.1101/2021.07.05.451205 — animal behavior and cognition — Posted on 2021-07-05

3423 Tracing the evolution of human gene regulation and its association with shifts in environment

Colbran, L. L.; Johnson, M. R.; Mathieson, I.; Capra, J. A.

10.1101/2021.07.05.451164 — genomics — Posted on 2021-07-05

3424 χ-separation: Magnetic susceptibility source separation toward iron and myelin mapping in the brain

Shin, H.-G.; Lee, J.; Yun, Y. H.; Yoo, S. H.; Jang, J.; Oh, S.-H.; Nam, Y.; Jung, S.; Kim, S.; Fukunaga, M.; Kim, W.; Choi, H. J.; Lee, J.

10.1101/2020.11.07.363796 — neuroscience — Posted on 2021-07-05

3425 Precise optical control of gene expression in C. elegans using genetic code expansion and Cre recombinase

Davis, L.; Radman, I.; Goutou, A.; Tynan, A.; Baxter, K.; Xi, Z.; O'Shea, J. M.; Chin, J. W.; Greiss, S.

10.1101/2020.05.02.072363 — neuroscience — Posted on 2021-07-05

3426 Cell type specific labeling and partial connectomes of dopaminergic circuits reveal non-synaptic communication and large-scale axonal remodeling after exposure to cocaine

Wildenberg, G. A.; Sorokina, A. M.; Koranda, J.; Monical, A.; Heer, C.; Sheffield, M.; Zhuang, X.; McGehee, D. S.; Kasthuri, N.

10.1101/2020.09.29.318881 — neuroscience — Posted on 2021-07-05

3427 Comprehensive evaluation of machine learning models and gene expression signatures for prostate cancer prognosis using large population cohorts

Li, R.; Jia, Z.

10.1101/2021.07.02.450975 — bioinformatics — Posted on 2021-07-05

3428 Coding and regulatory variants affect serum protein levels and common disease

Emilsson, V.; Gudmundsdottir, V.; Gudjonsson, A.; Karim, M. A.; Ilkov, M.; Staley, J. R.; Gudmundsson, E. F.; Jonsson, B. G.; Launer, L. J.; Lindeman, J. H.; Morton, N. M.; Aspelund, T.; Lamb, J. R.; Jennings, L. L.; Gudnason, V.

10.1101/2020.05.06.080440 — genetics — Posted on 2021-07-05

3429 Diet unmasks genetic variants that regulate lifespan in outbred Drosophila

Pallares, L. F.; Lea, A. J.; Han, C.; Filippova, E. V.; Andolfatto, P.; Ayroles, J. F.

10.1101/2020.10.19.346312 — evolutionary biology — Posted on 2021-07-05

3430 The role of ventromedial prefrontal cortex in reward valuation and future thinking during intertemporal choice

Ciaramelli, E.; De Luca, F.; Kwan, D.; Mok, J. N. Y.; Bianconi, F.; Knyagnytska, V.; Craver, C.; Green, L.; Myerson, J.; Rosenbaum, S.

10.1101/2021.03.15.435400 — neuroscience — Posted on 2021-07-05

3431 Peripheral CB1 receptor blockade acts as a memory enhancer through an adrenergic-dependent mechanism

Martinez-Torres, S.; Bergada-Martinez, A.; Ortega, J.; Galera-Lopez, L.; Hervera Abad, A.; Ortega-Alvaro, A.; Remmers, F.; Munoz-Moreno, E.; Soria, G.; del Rio, J. A.; Lutz, B.; Ruiz-Ortega, J. A.; Meana, J. J.; Maldonado, R.; Ozaita, A.

10.1101/2021.06.16.448227 — neuroscience — Posted on 2021-07-05

3432 Healthcare experience disrupts representational similarity between one's and others' pain in anterior insula

Corradi-Dell'Acqua, C.; Hofstetter, C.; Sharvit, G.; Hugli, O.; Vuilleumier, P.

10.1101/2021.07.01.450687 — neuroscience — Posted on 2021-07-05

3433 Parallel and recurrent cascade models as a unifying force for understanding sub-cellular computation

Harkin, E. F.; Shen, P. R.; Goel, A.; Richards, B. A.; Naud, R.

10.1101/2021.03.25.437091 — neuroscience — Posted on 2021-07-05

3434 A universal probabilistic spike count model reveals ongoing modulation of neural variability

Liu, D.; Lengyel, M.

10.1101/2021.06.27.450063 — neuroscience — Posted on 2021-07-05

3435 Neuroprotective mechanisms of red clover and soy isoflavones in Parkinson's disease models

de Rus Jacquet, A.; Ambaw, A.; Tambe, M. A.; Ma, S. Y.; Timmers, M.; Grace, M. H.; Wu, Q.-L.; Simon, J. E.; McCabe, G. P.; Lila, M. A.; Shi, R.; Rochet, J.-C.

10.1101/2020.12.01.391268 — pharmacology and toxicology — Posted on 2021-07-05

3436 Stat3 co-operates with mutant Ezh2Y641F to regulate gene expression and limit the anti-tumor immune response in melanoma

Zimmerman, S.; Nixon, S. J.; Chen, P. Y.; Raj, L.; Smith, S.; Paolini, R. L.; Lin, P. N.; Souroullas, G. P.

10.1101/2021.06.01.446580 — cancer biology — Posted on 2021-07-05

3437 PySTACHIO: Python Single-molecule TrAcking stoiCHiometry Intensity and simulatiOn, a flexible, extensible, beginner-friendly and optimized program for analysis of single-molecule microscopy

Shepherd, J. W.; Higgins, E.; Wollman, A. J.; Leake, M. C.

10.1101/2021.03.18.435952 — biophysics — Posted on 2021-07-05

3438 Inverse design of cholesterol attracting transmembrane helices reveals a paradoxical role of hydrophobic length

Methorst, J.; van Hilten, N.; Risselada, H. J.

10.1101/2021.07.01.450699 — biophysics — Posted on 2021-07-05

3439 Cytopath: Simulation based inference of differentiation trajectories from RNA velocity fields

Gupta, R.; Cerletti, D.; Gut, G.; Oxenius, A.; Claassen, M.

10.1101/2020.12.21.423801 — bioinformatics — Posted on 2021-07-05

3440 TransPi - a comprehensive TRanscriptome ANalysiS PIpeline for de novo transcriptome assembly

Rivera-Vicens, R. E.; Garcia Escudero, C.; Conci, N.; Eitel, M.; Wörheide, G.

10.1101/2021.02.18.431773 — bioinformatics — Posted on 2021-07-05

3441 Implicitly Learned Higher Order Associations Differentiates Recent and Remote Retrieval of Temporal Order Memory

Shridhar, S.; Singh, V. P.; Bhatt, R.; Kundu, S.; Balaji, J.

10.1101/2021.07.03.451031 — animal behavior and cognition — Posted on 2021-07-05

3442 Which Index Should I Use? A Comparison of Indices for Enclosure Use Studies

Brereton, J. E.; Fernandez, E. J.

10.1101/2021.07.04.451046 — animal behavior and cognition — Posted on 2021-07-05

3443 Sequestration of the exocytic SNARE Psy1 into multiprotein nodes reinforces polarized morphogenesis in fission yeast

Miller, K. E.; Magliozzi, J. O.; Picard, N. A.; Moseley, J. B.

10.1101/2020.05.01.072553 — cell biology — Posted on 2021-07-05

3444 Single-cell transcriptomics reveals a conserved metaplasia program in pancreatic injury

Ma, Z.; Lytle, N. K.; Chen, B.; Jyotsana, N.; Weiser Novak, S.; Cho, C. J.; Caplan, L.; Ben-Levy, O.; Neininger, A. C.; Burnette, D. T.; Trinh, V. Q.; Tan, M. C. B.; Patterson, E. A.; Arrojo e Drigo, R.; Giraddi, R. R.; Ramos, C.; Means, A. L.; Matsumoto, I.; Manor, U.; Mills, J. C.; Goldenring, J. R.; Lau, K.; Wahl, G.; DelGiorno, K. E.

10.1101/2021.04.09.439243 — cell biology — Posted on 2021-07-05

3445 Synaptic Encoding of Vestibular Sensation Regulates Movement Timing and Coordination

Hamling, K. R.; Harmon, K.; Greaney, M. R.; Dobler, Z.; Kimura, Y.; Higashijima, S.-i.; Schoppik, D.

10.1101/2021.07.05.451142 — neuroscience — Posted on 2021-07-05

3446 Behavioral evidence for nested central pattern generator control of Drosophila grooming

Ravbar, P.; Zhang, N.; Simpson, J. H.

10.1101/2020.09.15.298679 — neuroscience — Posted on 2021-07-05

3447 High-Speed, Cortex-Wide Volumetric Recording of Neuroactivity at Cellular Resolution using Light Beads Microscopy

Demas, J.; Manley, J.; Tejera, F.; Kim, H.; Martinez Traub, F.; Chen, B.; Vaziri, A.

10.1101/2021.02.21.432164 — neuroscience — Posted on 2021-07-05

3448 Perifornical Area Urocortin-3 Neurons Promote Infant-directed Neglect and Aggression

Autry, A. E.; Wu, Z.; Kohl, J.; Bambah-Mukku, D.; Rubinstein, N. D.; Marin-Rodriguez, B.; Carta, I.; Sedwick, V.; Dulac, C.

10.1101/697334 — neuroscience — Posted on 2021-07-05

3449 On the topochronic map of the human brain dynamics

Sorrentino, P.; Petkoski, S.; Sparaco, M.; Troisi Lopez, E.; Rucco, R.; Signoriello, E.; Baselice, F.; Bonavita, S.; Pirozzi, M. A.; Quarantelli, M.; Sorrentino, G.; Jirsa, V.

10.1101/2021.07.01.447872 — neuroscience — Posted on 2021-07-05

3450 Early life trauma leads to violent behavior and its inheritance by impairing local thyroid hormone availability in brain

Rawat, R. S.; Bhambri, A.; Pal, M.; Roy, A.; Jain, S.; Pillai, B.; Konar, A.

10.1101/2021.07.05.448713 — neuroscience — Posted on 2021-07-05

3451 Deficits in Behavioral and Neuronal Pattern Separation in Temporal Lobe Epilepsy

Madar, A. D.; Pfammatter, J. A.; Bordenave, J.; Plumley, E. I.; Ravi, S.; Cowie, M.; Wallace, E. P.; Hermann, B. P. D.; Maganti, R. K.; Jones, M. V.

10.1101/2020.02.13.948364 — neuroscience — Posted on 2021-07-05

3452 Implicit agency is related to gamma power changes in an automatic imitation task

Ulloa, J. L.; Vastano, R.; Jensen, O.; Brass, M.

10.1101/2021.06.28.448528 — neuroscience — Posted on 2021-07-05

3453 First detection of herpesvirus and frequency of mycoplasma infection in free-ranging Hermann s tortoises (Testudo hermanni), and in potential pet vectors

Ballouard, J.-m.; Bonnet, X.; Jourdan, J.; Martinez-Silvestre, A.; Gagno, S.; Fertard, B.; Caron, S.

10.1101/2021.01.22.427726 — zoology — Posted on 2021-07-05

3454 Machine Learning based Genome-Wide Association Studies for Uncovering QTL Underlying Soybean Yield and its Components

Yoosefzadeh Najafabadi, M.; Torabi, S.; Torkamaneh, D.; Tulpan, D.; Rajcan, I.; Eskandari, M.

10.1101/2021.06.24.449776 — plant biology — Posted on 2021-07-05

3455 PCaDB - a comprehensive and interactive database for transcriptomes from prostate cancer population cohorts

Li, R.; Jia, Z.

10.1101/2021.06.29.449134 — bioinformatics — Posted on 2021-07-05

3456 In vivo modelling of patient genetic heterogeneity identifies concurrent Wnt and PI3K activity as a potent driver of invasive cholangiocarcinoma growth.

Younger, N.; Wilson, M.; Jarman, E.; Meynert, A.; Grimes, G.; Gournopanos, K.; Waddell, S.; Tennant, P.; Wilson, D.; Guest, R.; Wigmore, S.; Acosta, J. C.; Kendall, T. J.; Taylor, M.; Sproul, D.; Mill, P.; Boulter, L.

10.1101/2021.07.05.449722 — cancer biology — Posted on 2021-07-05

3457 Identification of the Novel Pyroptosis-Related Gene Signature in Patients with Esophageal Adenocarcinoma

Zeng, R.; Huang, S.; Zhuo, Z.; Wu, H.; Sha, W.; Chen, H.

10.1101/2021.07.05.451093 — bioinformatics — Posted on 2021-07-05

3458 A new platform for high-throughput therapy testing on iPSC-derived, immature airway from Cystic Fibrosis Patients

Jiang, J. X.; Wellhauser, L.; Laselva, O.; Utkina, I.; Bozoky, Z.; Gunawardena, T.; Ngan, Z.; Xia, S.; Eckford, P. D. W.; Ratjen, F.; Moraes, T. J.; Parkinson, J.; Wong, A. P.; Bear, C.

10.1101/2021.07.05.451013 — genomics — Posted on 2021-07-05

3459 Long Range PCR-based deep sequencing for haplotype determination in mixed HCMV infections

Brait, N.; Kulekci, B.; Goerzer, I.

10.1101/2021.07.05.451103 — genomics — Posted on 2021-07-05

3460 Cyp26b1 restrains murine heart valve growth during development

Ahuja, N.; Hiltabildle, M. S.; Rajasekhar, H.; Daniel, E.; Barlow, H. R.; Voss, S.; Cleaver, O.; Maynard, C.

10.1101/2021.07.05.450958 — developmental biology — Posted on 2021-07-05

3461 Bioactivity, chemical profiling, and 16S rRNA-based phylogeny of haloalkaliphilic Nocardiopsis sp. GhM-HA-6 isolated from the Gulf of Khambhat

Thumar, J. T.; Trivedi, N.

10.1101/2021.07.05.451136 — microbiology — Posted on 2021-07-05

3462 Microbial diversity and sulfur cycling in an early earth analogue: From ancient novelty to modern commonality

Hahn, C. R.; Farag, I.; Murphy, C.; Podar, M.; Elshahed, M.; Youssef, N. H.

10.1101/2021.07.05.451135 — microbiology — Posted on 2021-07-05

3463 Aberrant motor contagion of emotions in psychopathy and high-functioning autism

Sun, L.; Lukkarinen, L.; Noppari, T.; Nazari-Farsani, S.; Putkinen, V. J.; Seppala, K.; Hudson, M.; Tani, P.; Lindberg, N.; Karlsson, H.; Hirvonen, J.; Salomaa, M.; Venetjoki, N.; Lauerma, H.; Tiihonen, J.; Nummenmaa, L.

10.1101/2021.07.05.450842 — neuroscience — Posted on 2021-07-05

3464 Transient beta modulates decision thresholds during human action-stopping

Muralidharan, V.; Aron, A. R.; Schmidt, R.

10.1101/2021.07.05.447605 — neuroscience — Posted on 2021-07-05

3465 Lightsheet Optical Tweezer (LOT) for Optical Manipulation of Microscopic Particles and Live Cells

Mondal, P. P.; Singh, A.; Joshi, P.; Basumatary, J.; Baro, N.

10.1101/2021.07.05.451038 — biophysics — Posted on 2021-07-05

3466 Hydrogel-based slow release of a receptor-binding domain subunit vaccine elicits neutralizing antibody responses against SARS-CoV-2

Gale, E. C.; Powell, A. E.; Roth, G. A.; Ou, B. S.; Meany, E. L.; Grosskopf, A. K.; Adamska, J.; Picece, V. C. T. M.; d'Aquino, A. I.; Pulendran, B.; Kim, P. S.; Appel, E.

10.1101/2021.03.31.437792 — bioengineering — Posted on 2021-07-05

3467 Estimating animal density with camera traps: a practitioner's guide of the REST model

Nakashima, Y.; Yajima, G.; Hongo, S.

10.1101/2021.05.18.444583 — ecology — Posted on 2021-07-05

3468 Spike protein cleavage-activation mediated by the SARS-CoV-2 P681R mutation: a case-study from its first appearance in variant of interest (VOI) A.23.1 identified in Uganda

Frazier, L.; Lubinski, B.; Tang, T.; Daniel, S.; Jaimes, J. A.; Whittaker, G.

10.1101/2021.06.30.450632 — microbiology — Posted on 2021-07-05

3469 An Immune Cell Atlas Reveals Dynamic COVID-19 Specific Neutrophil Programming Amenable to Dexamethasone Therapy

Sinha, S.; Rosin, N.; Arora, R.; Labit, E.; Jaffer, A.; Cao, L.; Farias, R.; Nguyen, A. P.; de Almeida, L. G. N.; Dufour, A.; Bromley, A.; McDonald, B.; Gillrie, M.; Fritzler, M. J.; Yipp, B.; Biernaskie, J.

10.1101/2021.04.18.440366 — immunology — Posted on 2021-07-05

3470 A memory-based theory of emotional disorders

Cohen, R. T.; Kahana, M. J.

10.1101/817486 — neuroscience — Posted on 2021-07-05

3471 CLOCK-induced upregulated HMGB1 resulting in circadian rhythms disruption of inflammatory microglia contributes to non-dipper hypertension in stressed rats

Zhang, S.

10.1101/2020.02.02.930800 — physiology — Posted on 2021-07-05

3472 To knot or not to knot: Multiple conformations of the SARS-CoV-2 frameshifting RNA element

Schlick, T.; Zhu, Q.; Dey, A.; Jain, S.; Yan, S.; Laederach, A.

10.1101/2021.03.31.437955 — biochemistry — Posted on 2021-07-05

3473 Disturbance-based management of ecosystem services and disservices in partial nitritation anammox biofilms

Suarez, C.; Sedlacek, C. J.; Gustavsson, D. J. I.; Eiler, A.; Modin, O.; Hermansson, M.; Persson, F.

10.1101/2021.07.05.451122 — microbiology — Posted on 2021-07-05

3474 Atypical development of subcortico-cortical effective connectivity in autism

Lorenzini, L.; van Wingen, G.; Cerliani, L.

10.1101/2021.07.02.450977 — neuroscience — Posted on 2021-07-05

3475 Generation, quality control, and analysis of the first genomically humanised knock-in mice for the ALS/FTD genes SOD1, TARDBP (TDP-43), and FUS

Devoy, A.; Price, G.; De Giorgio, F.; Bunton-Stasyshyn, R.; Thompson, D.; Gasco, S.; Allan, A.; Codner, G. F.; Nair, R. R.; Tibbit, C.; McLeod, R.; Ali, Z.; Noda, J.; Marrero-Gagliardi, A.; Brito-Armas, J. M.; Simon, M.; ONeill, E.; Harrison, J.; Atkins, G.; Corrochano, S.; Stewart, M.; Teboul, L.; Acevedo Arozena, A.; Fisher, E. M.; Cunningham, T. J.

10.1101/2021.07.05.451113 — neuroscience — Posted on 2021-07-05

3476 The Dilemma Of Disobedience: An ERP study

Fabre, E. F.; Causse, M.; Othon, M.; Vanderhenst, J.-B.

10.1101/2021.07.05.451127 — neuroscience — Posted on 2021-07-05

3477 Investigating facial information content in the hand area of individuals with a congenital and acquired missing hand

Root, V.; Muret, D.; Arribas, M.; Amoruso, E.; Thornton, J.; Tarall-Jozwiak, A.; Tracey, I.; Makin, T.

10.1101/2021.07.05.451126 — neuroscience — Posted on 2021-07-05

3478 Direct neuronal reprogramming by temporal identity factors

Boudreau-Pinsonneault, C.; Javed, A.; Fries, M.; Mattar, P.; Cayouette, M.

10.1101/2021.07.05.451124 — neuroscience — Posted on 2021-07-05

3479 CXCL17 is an endogenous inhibitor of CXCR4 via a novel mechanism of action

White, C. W.; Kilpatrick, L. E.; Dale, N.; Abhayawardana, R. S.; Dekkers, S.; Stocks, M. J.; Pfleger, K. D.; Hill, S. J.

10.1101/2021.07.05.451109 — pharmacology and toxicology — Posted on 2021-07-05

3480 Multifaceted roles of SAMHD1 in cancer

McLaughlin, K.-M.; Cinatl, J.; Wass, M. N.; Michaelis, M.

10.1101/2021.07.03.451003 — cancer biology — Posted on 2021-07-05

3481 Meta-analysis of exhausted CD8+ T cells from Homo sapiens and Mus musculus provides robust targets for immunotherapy

Zhang, L.; Guo, Y.; Nishi, H.

10.1101/2021.07.05.451111 — bioinformatics — Posted on 2021-07-05

3482 Comprehensive evaluation of machine learning models and gene expression signatures for prostate cancer prognosis using large population cohorts

Li, R.; Jia, Z.

10.1101/2021.07.02.450975 — bioinformatics — Posted on 2021-07-05

3483 Steps to (s)-stereoisomers: Rationalization of a standard Short-chain dehydrogenase for the reduction of multiple pharmaceutical ketone intermediates

Shanbhag, A. P.; Rajagopal, S.; Katagihallimath, N.; Ghatak, A.; S., R.; Datta, S.

10.1101/2021.07.05.449867 — biochemistry — Posted on 2021-07-05

3484 Stable Isotope Tracing In Vivo Reveals A Metabolic Bridge Linking The Microbiota To Host Histone Acetylation

Lund, P. J.; Gates, L. A.; Leboeuf, M.; Smith, S. A.; Chau, L.; Friedman, E. S.; Lopes, M.; Saiman, Y.; Kim, M. S.; Petucci, C.; Allis, C. D.; Wu, G. D.; Garcia, B. A.

10.1101/2021.07.05.450926 — biochemistry — Posted on 2021-07-05

3485 Meta-analysis of tree diversity effects on the abundance, diversity and activity of herbivores' enemies

Stemmelen, A.; Jactel, H.; Brockerhoff, E.; Castagneyrol, B.

10.1101/2021.07.05.451117 — ecology — Posted on 2021-07-05

3486 Sand dropseed (Sporobolus cryptandrus) - A new pest in Eurasian sand areas?

Torok, P.; Schmidt, D.; Batori, Z.; Aradi, E.; Kelemen, A.; Habenczyus, A. A.; Diaz, P.; Tolgyesi, C.; Pal, R. W.; Balogh, N.; Toth, E.; Matus, G.; Taborska, J.; Sramko, G.; Laczko, L.; Jordan, S.; Sonkoly, J.

10.1101/2021.07.05.451115 — ecology — Posted on 2021-07-05

3487 ECM-integrin signalling instructs cellular position-sensing to pattern the early mouse embryo

Kim, E. J. Y.; Sorokin, L.; Hiiragi, T.

10.1101/2021.07.05.450860 — developmental biology — Posted on 2021-07-05

3488 Periosteum-derived podoplanin-expressing stromal cells regulate nascent vascularization during epiphyseal marrow development

Tamura, S.; Mukaide, M.; Katsuragi, Y.; Fujii, W.; Odaira, K.; Suzuki, N.; Okamoto, S.; Suzuki, A.; Kanematsu, T.; Katsumi, A.; Takagi, A.; Suzuki-Inoue, K.; Matsushita, T.; Kojima, T.; Hayakawa, F.

10.1101/2021.07.05.451096 — developmental biology — Posted on 2021-07-05

3489 Embigin deficiency leads to delayed embryonic lung development and high neonatal mortality

Talvi, S.; Jokinen, J.; Sipila, K. H.; Rappu, P.; Zhang, F.; Poutanen, M.; Rantakari, P.; Heino, J.

10.1101/2021.07.05.451131 — developmental biology — Posted on 2021-07-05

3490 The E3 Ubiquitin Ligase Mindbomb1 controls zebrafish Planar Cell Polarity

Saraswathy, V. M.; Sharma, P.; Kurup, A. J.; Poles, S.; Poulain, M.; Fürthauer, M.

10.1101/2021.07.05.451064 — developmental biology — Posted on 2021-07-05

3491 A chromatin phase transition protects mitotic chromosomes against microtubule perforation

Schneider, M. W. G.; Gibson, B. A.; Otsuka, S.; Spicer, M. F. D.; Petrovic, M.; Blaukopf, C.; Langer, C. C. H.; Doolittle, L. K.; Rosen, M. K.; Gerlich, D. W.

10.1101/2021.07.05.450834 — cell biology — Posted on 2021-07-05

3492 Reversal of the renal hyperglycemic memory by targeting sustained tubular p21 expression

Al-Dabet, M. M.; Shahzad, K.; Elwakiel, A.; Sulaj, A.; Kopf, S.; Bock, F.; Gadi, I.; Zimmermann, S.; Rana, R.; Krishnan, S.; Gupta, D.; Nazir, S.; Baber, R.; Scholz, M.; Geffers, R.; Mertens, P. R.; Nawroth, P. P.; Griffin, J.; Dockendorff, C.; Kohli, S.; Isermann, B.

10.1101/2021.07.05.450846 — molecular biology — Posted on 2021-07-05

3493 Novel microbial syntrophies identified by longitudinal metagenomics

Raguideau, S.; Trego, A.; Farrell, F.; Collins, G.; Quince, C.; Soyer, O. S.

10.1101/2021.07.05.451125 — microbiology — Posted on 2021-07-05

3494 Naturalistic Audiovisual Stimulation Reveals the Topographic Organization of Human Auditory Cortex

Hedger, N.; Knapen, T.

10.1101/2021.07.05.447566 — neuroscience — Posted on 2021-07-05

3495 Insula to mPFC reciprocal connectivity differentially underlies novel taste neophobic response and learning

Kayyal, H.; Chandran, S. K.; Yiannakas, A.; Gould, N.; Khamaisy, M.; Rosenblum, K.

10.1101/2021.07.05.451133 — neuroscience — Posted on 2021-07-05

3496 Topography-induced large-scale anti-parallel collective migration in vascular endothelium

Leclech, C.; Gonzalez-Rodriguez, D.; Villedieu, A.; Lok, T.; Déplanche, A.-M.; Barakat, A. I.

10.1101/2021.07.05.451106 — biophysics — Posted on 2021-07-05

3497 Identification of potential carboxylic acid-containing drug candidate to design novel competitive NDM inhibitors: An in-silico approach comprising combined virtual screening and molecular dynamics simulation

Anbarasu, A.; Veeraraghavan, B.; Vasudevan, K.; Basu, S.; Arumugam, A.; Naha, A.; Ramaiah, S.

10.1101/2021.07.05.451101 — bioinformatics — Posted on 2021-07-05

3498 SELECTION DRIVES THE EVOLUTION OF CONVERGENT GENE EXPRESSION CHANGES DURING TRANSITIONS TO CO-SEXUALITY IN HAPLOID SEXUAL SYSTEMS

Cossard, G.; Godfroy, O.; Nehr, Z.; Crouaud, C.; Cock, J. M.; Lipinska, A. P.; Coelho, S. M.

10.1101/2021.07.05.451104 — evolutionary biology — Posted on 2021-07-05

3499 Polygenic routes lead to parallel altitudinal adaptation in Heliosperma pusillum (Caryophyllaceae)

Szukala, A.; Lovegrove-Walsh, J.; Luqman, H.; Fior, S.; Wolfe, T. M.; Frajman, B.; Schoenswetter, P.; Paun, O.

10.1101/2021.07.05.451094 — evolutionary biology — Posted on 2021-07-05

3500 Transcriptomic response of Cinachyrella cf. cavernosa sponges to spatial competition

Deshpande, A.; Rivera-Vicens, R. E.; Thakur, N. L.; Wörheide, G.

10.1101/2021.07.05.451097 — ecology — Posted on 2021-07-05

3501 circFL-seq reveals full-length circular RNAs with rolling circular reverse transcription and nanopore sequencing

Liu, Z.; Tao, C.; Li, S.; Du, M.; Bai, Y.; Hu, X.; Li, Y.; Chen, J.; Yang, E.

10.1101/2021.07.05.451107 — molecular biology — Posted on 2021-07-05

3502 A bacterial derived plant- mimicking cytokinin hormone regulates social behaviour in a rice pathogen

Deb, S.; Kumar, C.; Kumar, R.; Kaur, A.; Ghosh, P.; Jha, G.; Patil, P. B.; Chatterjee, S.; Patel, H. K.; Sonti, R. V.

10.1101/2021.07.05.451090 — microbiology — Posted on 2021-07-05

3503 Global evolutionary dynamics and resistome analysis of Clostridioides difficile ribotype 017

Imwattana, K.; Putsathit, P.; Leepattarakit, T.; Kiratisin, P.; Riley, T. V.; Knight, D. R.

10.1101/2021.07.04.451084 — microbiology — Posted on 2021-07-05

3504 Efficient breeding of industrial brewing yeast strains using CRISPR/Cas9-aided mating-type switching

Krogerus, K.; Fletcher, E.; Rettberg, N.; Gibson, B.; Preiss, R.

10.1101/2021.07.05.450511 — microbiology — Posted on 2021-07-05

3505 Coding of interceptive saccades in parietal cortex of macaque monkeys

Churan, J.; Kaminiarz, A.; Schwenk, J. C. B.; Bremmer, F.

10.1101/2021.07.05.451092 — neuroscience — Posted on 2021-07-05

3506 Divergent effects of absolute evidence magnitude on decision accuracy and confidence in perceptual judgements

Ko, Y. H.; Feuerriegel, D. C.; Turner, W.; Overhoff, H.; Niessen, E.; Stahl, J.; Hester, R.; Fink, G. R.; Weiss, P. H.; Bode, S.

10.1101/2021.07.04.451079 — neuroscience — Posted on 2021-07-05

3507 Early life trauma leads to violent behavior and its inheritance by impairing local thyroid hormone availability in brain

Konar, A.; Rawat, R. S.; Bhambri, A.; Pal, M.; Roy, A.; Jain, S.; Pillai, B.

10.1101/2021.07.05.448713 — neuroscience — Posted on 2021-07-05

3508 The Cl- channel TMEM16A controls the generation of cochlear Ca2+ waves and promotes the refinement of auditory brainstem networks

Maul, A.; Jovanovic, S.; Huebner, A.-K.; Strenzke, N.; Moser, T.; Rübsamen, R.; Hübner, C. A.

10.1101/2021.07.05.451099 — neuroscience — Posted on 2021-07-05

3509 ProXs drive the formation of membraneless organelles in plants

Zhang, H.; Peng, F.; Liu, Y.; Deng, H.; Fang, X.

10.1101/2021.07.04.451080 — plant biology — Posted on 2021-07-05

3510 Molecular Determinants of Complexin Clamping in Reconstituted Single-Vesicle Fusion

Bera, M.; Ramakrishnan, S.; Coleman, J.; Krishnakumar, S. S.; Rothman, J. E.

10.1101/2021.07.05.451112 — biophysics — Posted on 2021-07-05

3511 C-STEM: ENGINEERING NICHE-LIKE MICRO-COMPARTMENTS FOR OPTIMAL AND SCALE-INDEPENDENT EXPANSION OF HUMAN PLURIPOTENT STEM CELLS IN BIOREACTORS

Cohen, P. J. R.; Luquet, E.; Pletenka, J.; Leonard, A.; Warter, E.; Gurchenkov, B.; Carrere, J.; Rieu, C.; Hardouin, J.; Moncaubeig, F.; Lanero, M.; Quelennec, E.; Wurtz, H.; Jamet, E.; Demarco, M.; banal, C.; Van Liedekerke, P.; Nassoy, P.; Feyeux, M.; Lefort, N.; Alessandri, k.

10.1101/2021.07.05.451086 — bioengineering — Posted on 2021-07-05

3512 High Sensitivity and Low-Cost Flavin luciferase (FLUX)-based Reporter Gene for Mammalian Cell Expression

Phonbuppha, J.; Tinikul, R.; Ohmiya, Y.; Chaiyen, P.

10.1101/2021.07.04.451075 — biochemistry — Posted on 2021-07-05

3513 Fly Cell Atlas: a single-cell transcriptomic atlas of the adult fruit fly

Li, H.; Janssens, J.; De Waegeneer, M.; Kolluru, S. S.; Davie, K.; Gardeux, V.; Sealens, W.; David, F.; Brbic, M.; Leskovec, J.; McLaughlin, C.; Xie, Q.; Jones, R.; Brueckner, K.; Shim, J.; Tattikota, S. G.; Schnorrer, F.; Rust, K.; Nystul, T.; Carvalho-Santos, Z.; Ribeiro, C.; Pal, S.; Przytycka, T. M.; Allen, A.; Goodwin, S.; Berry, C.; Fuller, M. T.; White-Cooper, H.; Matunis, E.; DiNardo, S.; Galenza, A.; O'Brien, L. E.; Dow, J. A. T.; FCA Consortium, ; Jasper, H.; Oliver, B.; Perrimon, N.; Deplancke, B.; Quake, S.; Luo, L.; Aerts, S.

10.1101/2021.07.04.451050 — genomics — Posted on 2021-07-05

3514 ribofootPrinter: A precision python toolbox for analysis of ribosome profiling data

Guydosh, N. R.

10.1101/2021.07.04.451082 — genomics — Posted on 2021-07-05

3515 Phylogenomic analysis of Uganda influenza type-A viruses to assess their relatedness to the vaccine strains and other Africa viruses: a molecular epidemiology study.

Nabakooza, G.; Owuor, D. C.; R. de Laurent, Z.; Owor, N.; Kayiwa, J. T.; Jjingo, D.; Agoti, C. N.; Nokes, D. J.; Kateete, D. P.; Kitayimbwa, J. M.; Frost, S. D. W.; Lutwama, J. J.

10.1101/2021.07.05.451078 — evolutionary biology — Posted on 2021-07-05

3516 Gut microbial diversity in stingless bees is linked to host wing size and is influenced by geography

Liu, H.; Hall, M. A.; Brettell, L.; Halcroft, M.; Wang, J.; Nacko, S.; Spooner-Hart, R.; Cook, J.; Riegler, M.; Singh, B.

10.1101/2021.07.04.451070 — ecology — Posted on 2021-07-05

3517 The BLMP-1 transcription factor promotes oscillatory gene expression to achieve timely molting

Hauser, Y. P.; Meeuse, M. W.; Gaidatzis, D.; Grosshans, H.

10.1101/2021.07.05.450828 — developmental biology — Posted on 2021-07-05

3518 A new transgene mouse model using an extravesicular EGFP tag to elucidate the in vivo function of extracellular vesicles

Noegaard, M. O.; Steffensen, L. B.; Hansen, D.; Fuchtbauer, E.-M.; Engelund, M. B.; Dimke, H.; Andersen, D. C.; Svenningsen, P.

10.1101/2021.07.05.451120 — molecular biology — Posted on 2021-07-05

3519 A SUBTILISIN-LIKE SERINE PROTEASE1 (OsSUBSrP1), plays an important role in the wax and cutin pathway, is essential for panicle development in rice

Ali, A.; Wu, T.; Zhang, H.; Xu, P.; Zafar, S. A.; Liao, Y.; Chen, X.; Liu, Y.; Wang, W.; Wu, X.

10.1101/2021.07.04.451081 — molecular biology — Posted on 2021-07-05

3520 Examining the effects of an anti-Salmonella bacteriophage preparation, BAFASAL, on ex vivo human gut microbiome composition and function using a multi-omics approach

Mayne, J.; Zhang, X.; Butcher, J.; Walker, K.; Ning, Z.; Wojcik, E.; Dastych, J.; Stintzi, A.; Figeys, D.

10.1101/2021.07.04.451072 — microbiology — Posted on 2021-07-05

3521 Isolation and characterization of a Cyprinid herpesvirus strain YZ01 from apparently healthy goldfish after rising water temperature

Wang, F.; Xu, Y.; Zhou, Y.; Ding, C.; Duan, H.

10.1101/2021.07.05.451087 — microbiology — Posted on 2021-07-05

3522 Tactile suppression stems from sensation-specific sensorimotor predictions

Fuehrer, E.; Voudouris, D.; Lezkan, A.; Drewing, K.; Fiehler, K.

10.1101/2021.07.04.451060 — neuroscience — Posted on 2021-07-05

3523 Pro-inflammatory Cytokine GM-CSF Improves Learning/Memory and Brain Pathology in Dp16 Down Syndrome Mice and Improves Learning/Memory in Wild-Type Mice

Ahmed, M. M.; Wang, A.; Elos, M.; Chial, H.; Sillau, S.; Solano, A.; Coughlan, C.; Aghili, L.; Anton, P.; Markham, N.; Adame, V.; Gardiner, K.; Boyd, T.; Potter, H.

10.1101/2021.07.04.451073 — neuroscience — Posted on 2021-07-05

3524 Frequency-specific coactivation patterns in resting-state and their alterations in schizophrenia: an fMRI study

Yang, H.; Zhang, H.; Di, X.; Wang, S.; Meng, C.; Tian, L.; Biswal, B. B.

10.1101/2021.07.04.451042 — neuroscience — Posted on 2021-07-05

3525 Pseudocritical and Precritical States in Brain Dynamics

Gu, L.; Wu, R.

10.1101/2021.07.04.451067 — neuroscience — Posted on 2021-07-05

3526 Towards a Neurometric-based Construct Validity of Trust

Chen, P.-H. A.; Fareri, D.; Guroglu, B.; Delgado, M. R.; Chang, L. J.

10.1101/2021.07.04.451074 — neuroscience — Posted on 2021-07-05

3527 Automated verification, assembly, and extension of GBM stem cell network model with knowledge from literature and data

Holtzapple, E.; Cochran, B.; Miskov-Zivanov, N.

10.1101/2021.07.04.451062 — systems biology — Posted on 2021-07-05

3528 Detection of Ramularia collo-cygni from barley (Hordeum vulgare) in Australia using triplex quantitative and digital PCR

Knight, N.; Moslemi, A.; Begum, F.; Dodhia, K.; Covarelli, L.; Hills, A.; Lopez-Ruiz, F. J.

10.1101/2021.07.04.451076 — plant biology — Posted on 2021-07-05

3529 Functional characterisation of the Nep1-like protein effectors of the necrotrophic pathogen - Alternaria brassicae

Duhan, D.; Gajbhiye, S.; Jaswal, R.; Singh, R. P.; Sharma, T. R.; Rajarammohan, S.

10.1101/2021.07.04.450447 — plant biology — Posted on 2021-07-05

3530 PHENOTYPIC CHARACTERIZATION OF TWO NOVEL CELL LINE MODELS OF CASTRATION RESISTANT PROSTATE CANCER.

Haffner, M. C.; Bhamidipati, A.; Tsai, H. K.; Esopi, D. M.; Vaghasia, A. M.; Low, J.-Y.; Patel, R. A.; Guner, G.; Pham, M.-T.; Castagna, N.; Hicks, J.; Wyhs, N.; Aebersold, R.; De Marzo, A. M.; Nelson, W. G.; Guo, T.; Yegnasubramanian, S.

10.1101/2021.07.04.450352 — cancer biology — Posted on 2021-07-05

3531 Deleting in vivo β-catenin degradation domain in mouse hepatocytes drives hepatocellular carcinoma or hepatoblastoma-like tumors

Loesch, R.; Caruso, S.; Paradis, V.; Godard, C.; Gougelet, A.; Picard, S.; Perret, C.; Taketo, M. M. M.; Zucman-Rossi, J.; Colnot, S.

10.1101/2021.07.04.450836 — cancer biology — Posted on 2021-07-05

3532 Based on the identification of tumor antigens and immune subtypes in renal clear cell carcinoma for mRNA vaccine development

Zhang, S.; Xiong, Y.; Kang, S.; Mao, C.; Wang, Y.; Zeng, Z.; Peng, J.; Ouyang, Y.

10.1101/2021.07.04.451033 — bioinformatics — Posted on 2021-07-05

3533 Open-source personal pipetting robots with live-cell incubation and microscopy compatibility

Dettinger, P.; Kull, T.; Arekatla, G.; Ahmed, N.; Zhang, Y.; Schneiter, F.; Wehling, A.; Schirmacher, D.; Kawamura, S.; Loeffler, D.; Schroeder, T.

10.1101/2021.07.04.448641 — bioengineering — Posted on 2021-07-05

3534 Self-organization of collective escape in pigeon flocks

Papadopoulou, M.; Hildenbrandt, H.; Sankey, D. W. E.; Portugal, S. J.; Hemelrijk, C. K.

10.1101/2021.07.04.450902 — animal behavior and cognition — Posted on 2021-07-05

3535 Which Index Should I Use? A Comparison of Indices for Enclosure Use Studies

Brereton, J. E.; Fernandez, E. J.

10.1101/2021.07.04.451046 — animal behavior and cognition — Posted on 2021-07-05

3536 Novel measures of Morris water maze performance that use vector field maps to assess accuracy, uncertainty, and intention of navigational searches

Prabod Kumar, M.; Mehrotra, D.; Nruythyathi, N.; Almeida-Filho, D.; Lee, Y.-S.; Silva, A. J.; Jayaprakash, B.

10.1101/2021.07.04.451032 — animal behavior and cognition — Posted on 2021-07-05

3537 Population bottlenecks constrain microbiome diversity and host genetic variation impeding fitness

Oersted, M.; Yashiro, E.; Hoffmann, A. A.; Kristensen, T. N.

10.1101/2021.07.04.450854 — evolutionary biology — Posted on 2021-07-05

3538 Convergent evolution of venom gland transcriptomes across Metazoa

Zancolli, G.; Reijnders, M.; Waterhouse, R.; Robinson-Rechavi, M.

10.1101/2021.07.04.451048 — evolutionary biology — Posted on 2021-07-05

3539 Fine human genetic map based on UK10K data set

Hao, Z.; Du, P.; Pan, Y.-H.; Li, H.

10.1101/809020 — evolutionary biology — Posted on 2021-07-05

3540 Mechanics defines the spatial pattern of compensatory proliferation

Kawaue, T.; Yow, I.; Le, A. P.; Lou, Y.; Loberas, M.; Shagirov, M.; Prost, J.; Hiraiwa, T.; Ladoux, B.; Toyama, Y.

10.1101/2021.07.04.451019 — cell biology — Posted on 2021-07-05

3541 Characterization of Animal Movement Patterns using Information Theory: a Primer

Owoeye, K. A.; Musolesi, M.; Hailes, S.

10.1101/311241 — ecology — Posted on 2021-07-05

3542 Pipeline to detect the positional and directional relationship between transposable elements and adjacent genes in host genome

Meguerditchian, C.; Ergun, A.; DECROOCQ, V.; LEFEBVRE, M.; Bui, Q. T.

10.1101/2021.02.25.432867 — bioinformatics — Posted on 2021-07-05

3543 Pipeline to detect the positional relationship between transposable elements and adjacent genes in host genome

Meguerditchian, C.; Ergun, A.; DECROOCQ, V.; LEFEBVRE, M.; Bui, Q. T.

10.1101/2021.02.25.432867 — bioinformatics — Posted on 2021-07-05

3544 Comparative Analysis of non-coding small-RNAs in Pseudomonas aeruginosa Keratitis Strains with Different Antibiotic Susceptibility

Kandasamy, K.; Lalitha, P.; Devarajan, B.

10.1101/2021.07.02.450871 — genomics — Posted on 2021-07-05

3545 Coding and regulatory variants affect serum protein levels and common disease

Emilsson, V.; Gudmundsdottir, V.; Ilkov, M.; Staley, J. R.; Gudmundsson, E. F.; Launer, L. J.; Lindeman, J. H.; Morton, N. M.; Aspelund, T.; Lamb, J. R.; Jennings, L. L.; Gudnason, V.; Gudjonsson, A.; Karim, M. A.; Jonsson, B. G.

10.1101/2020.05.06.080440 — genetics — Posted on 2021-07-05

3546 Efficient prediction of microplastic counts from mass measurements

Tan, S.; Taylor, J. A.; Passeport, E.

10.1101/2021.01.04.425187 — ecology — Posted on 2021-07-05

3547 TLR4 regulation in human fetal membranes as an explicative mechanism of a pathological preterm case.

Belville, C.; Ponelle-Chachuat, F.; Rouzaire, M.; Gross, C.; Pereira, B.; Gallot, D.; Sapin, V.; BLANCHON, L.

10.1101/2021.06.28.450131 — cell biology — Posted on 2021-07-05

3548 Single-cell RNA sequencing-based characterization of resident lung mesenchymal stromal cells in bronchopulmonary dysplasia

Mizikova, I.; Lesage, F.; Cyr-Depauw, C.; Cook, D. P.; Hurskainen, M.; Hanninen, S.; Vadivel, A.; Bardin, P.; Zhong, S.; Carpen, O.; Vanderhyden, B. C.; Thebaud, B.

10.1101/2021.06.18.448928 — cell biology — Posted on 2021-07-05

3549 Fluctuations in TCR and pMHC interactions regulate T cell activation

Egan, J. R.; Abu-Shah, E.; Dushek, O.; Elliott, T.; MacArthur, B.

10.1101/2021.02.09.430441 — immunology — Posted on 2021-07-05

3550 Spatial maps in olfactory cortex during olfactory navigation

Poo, C.; Agarwal, G.; Bonacchi, N.; Mainen, Z. F.

10.1101/2020.02.18.935494 — neuroscience — Posted on 2021-07-05

3551 Hippocampal sharp wave-ripples and the associated sequence replay emerge from structured synaptic interactions in a network model of area CA3

Ecker, A.; Bagi, B.; Vertes, E.; Steinbach-Nemeth, O.; Karlocai, M. R.; Papp, O. I.; Miklos, I.; Hajos, N.; Freund, T. F.; Gulyas, A. I.; Kali, S.

10.1101/2021.02.18.431868 — neuroscience — Posted on 2021-07-05

3552 Predicting speech from a cortical hierarchy of event-based timescales

Schmitt, L.-M.; Erb, J.; Tune, S.; Rysop, A.; Hartwigsen, G.; Obleser, J.

10.1101/2020.12.19.423616 — neuroscience — Posted on 2021-07-05

3553 Multi-omics-based label-free metabolic flux inference reveals obesity-associated dysregulatory mechanisms in liver glucose metabolism

Uematsu, S.; Ohno, S.; Tanaka, K. Y.; Hatano, A.; Kokaji, T.; Ito, Y.; Kubota, H.; Hironaka, K.-i.; Suzuki, Y.; Matsumoto, M.; Nakayama, K. I.; Hirayama, A.; Soga, T.; Kuroda, S.

10.1101/2021.06.21.449220 — systems biology — Posted on 2021-07-05

3554 Accelerating leaf area measurement using a volumetric approach

Haghshenas, A.; Emam, Y.

10.1101/2021.07.03.451015 — plant biology — Posted on 2021-07-05

3555 Gasdermin B over-expression arbitrates HER2-targeted therapy resistance by inducing protective autophagy

Gamez-Chiachio, M.; Molina-Crespo, A.; Ramos-Nebot, C.; Martinez-Val, J.; Martinez, L.; Gassner, K.; Llobet, F. J.; Gonzalo-Consuegra, C.; Cordani, M.; Bernado-Morales, C.; Diaz, E.; Rojo-Sebastian, A.; Trivino, J. C.; Sanchez, L.; Rodriguez-Barrueco, R.; Arribas, J.; Llobet-Navas, D.; Sarrio, D.; Moreno-Bueno, G.

10.1101/2021.07.01.450506 — cancer biology — Posted on 2021-07-05

3556 Crop loss identification at field parcel scale using satellite remote sensing and machine learning

Hiremath, S.; Wittke, S.; Palosuo, T.; Kaivosoja, J.; Tao, F.; Proll, M.; Puttonen, E.; Peltonen-Sainio, P.; Marttinen, P.; Mamitsuka, H.

10.1101/2021.05.07.443072 — bioinformatics — Posted on 2021-07-05

3557 Fitness benefits of providing services to others: Grooming predicts survival in a neotropical primate

KAJOKAITE, K.; Whalen, A.; Koster, J.; Perry, S.

10.1101/2020.08.04.235788 — animal behavior and cognition — Posted on 2021-07-05

3558 Antagonistic plants preferentially target arbuscular mycorrhizal fungi that are highly connected to mutualistic plants

Gomes, S.; Fortuna, M.; Bascompte, J.; Merckx, V.

10.1101/867259 — ecology — Posted on 2021-07-05

3559 Use of high-refractive index hydrogels and tissue clearing for large biological sample imaging

Richardson, A.; Fok, S.; Lee, V.; Rye, K.-A.; Di Girolamo, N.; Cochran, B. J.

10.1101/2020.01.22.905695 — pathology — Posted on 2021-07-05

3560 GLIS1 regulates trabecular meshwork function and intraocular pressure and is associated with glaucoma in humans

Nair, S.; Srivastava, C.; Brown, R. V.; Koli, S.; Choquet, H.; Kang, H. S.; Kuo, Y.-M.; Grimm, S. A.; Sutherland, C.; Badea, A.; Johnson, G. A.; Zhao, Y.; Yin, J.; Okamoto, K.; Kizhatil, K.; Borras, T.; Zode, G.; Clark, G.; Chakrabarti, S.; John, S. W. M.; Jorgenson, E.; Jetten, A. M.

10.1101/2021.07.02.450719 — molecular biology — Posted on 2021-07-05

3561 Dynamic aspects of plant water potential revealed by a microtensiometer

Pagay, V. V.

10.1101/2021.06.23.449675 — plant biology — Posted on 2021-07-05

3562 The role of Vitamin C in the energy supply of cells Hypothetical structure for energy transformation

Hunyady, J. P.

10.1101/2020.07.21.214403 — biochemistry — Posted on 2021-07-05

3563 Characterisation of the transcriptional dynamics underpinning the function, fate, and migration of the mouse Anterior Visceral Endoderm

Thowfeequ, S.; Fiorentino, J.; Hu, D.; Solovey, M.; Ruane, S.; Whitehead, M.; Vanhaesebroeck, B.; Scialdone, A.; Srinivas, S.

10.1101/2021.06.25.449902 — developmental biology — Posted on 2021-07-05

3564 Mice and primates use distinct strategies for visual segmentation

Luongo, F. J.; Liu, L.; Ho, C. L. A.; Hesse, J. K.; Wekselblatt, J. B.; Lanfranchi, F.; Huber, D. K.; Tsao, D. Y.

10.1101/2021.07.04.451059 — neuroscience — Posted on 2021-07-05

3565 Dopaminergic axon tracts within a hyaluronic acid hydrogel encasement for implantation to restore the nigrostriatal pathway

Gordian-Velez, W. J.; Browne, K. D.; Galarraga, J. H.; Duda, J. E.; Espana, R. A.; Chen, H. I.; Burdick, J. A.; Cullen, D. K.

10.1101/2021.07.03.451006 — bioengineering — Posted on 2021-07-04

3566 De novo human brain enhancers created by single nucleotide mutations

Li, S.; Hannenhalli, S.; Ovcharenko, I.

10.1101/2021.07.04.451055 — genomics — Posted on 2021-07-05

3567 Gene drive that results in addiction to a temperature sensitive version of an essential gene triggers population collapse in Drosophila

Oberhofer, G.; Hay, B.; Ivy, T.

10.1101/2021.07.03.451005 — genetics — Posted on 2021-07-04

3568 Severe neural tube defects due to failure of closure initiation can arise without abnormality of neuroepithelial convergent extension

Nychyk, O.; Galea, G. L.; Mole, M. J.; Savery, D.; Greene, N.; Stanier, P.; Copp, A. J.

10.1101/2021.07.04.451044 — developmental biology — Posted on 2021-07-04

3569 BOLD fMRI signals of visual white matter encode visuotopic information and predict effective connectivity between visual areas

Wang, H.; Wang, X.; Wang, Y.; Zhang, D.; Zhou, Y.; Qiu, B.; Zhang, P.

10.1101/2021.06.30.450520 — neuroscience — Posted on 2021-07-04

3570 Single-cell sequencing of the adult killifish (N. furzeri) brain identifies an atypical progenitor, glial and neuronal heterogeneity

Ayana, R.; Van houcke, J.; Zandecki, C.; Marien, V.; Seuntjens, E.; Arckens, L.

10.1101/2021.07.04.450918 — neuroscience — Posted on 2021-07-04

3571 Effect of artificial light at night on sleep and metabolism in weaver birds

YADAV, A.; KUMAR, R.; TIWARI, J.; VAISH, V.; MALIK, S.; rani, s.

10.1101/2021.07.03.451020 — zoology — Posted on 2021-07-04

3572 Trycycler: consensus long-read assemblies for bacterial genomes

Wick, R. R.; Judd, L. M.; Cerdeira, L. T.; Hawkey, J.; Meric, G.; Vezina, B.; Wyres, K. L.; Holt, K. E.

10.1101/2021.07.04.451066 — bioinformatics — Posted on 2021-07-04

3573 Accurate Automatic Glioma Segmentation in Brain MRI images Based on CapsNet

Jalili Aziz, M.; Amiri Tehrani Zadeh, M. A.; Farnia, P.; Alimohammadi, M.; Makki Abadi, B.; Ahmadian, A.; Alirezaie, J.

10.1101/2021.07.03.450931 — bioengineering — Posted on 2021-07-04

3574 Quantifying unusual neurological movement phenotypes in collective movement phenotypes

Owoeye, K.; Musolesi, M.; Hailes, S.

10.1101/2021.07.03.450923 — animal behavior and cognition — Posted on 2021-07-04

3575 Synchronized swarming: Harmonic convergence and acoustic mating dynamics in the malaria mosquito Anopheles gambiae

Garcia Castillo, S. S.; Pritts, K. S.; Krishnan, R. S.; Harrington, L. C.; League, G. P.

10.1101/2021.07.03.451017 — animal behavior and cognition — Posted on 2021-07-04

3576 eQTL mapping using allele-specific gene expression

Zhabotynsky, V.; Huang, L.; Little, P.; Hu, Y.; Pardo Manuel de Villena, F. F.; Zou, F.; Sun, W.

10.1101/2021.07.03.450987 — genomics — Posted on 2021-07-04

3577 Promoter architecture links gene duplication with transcriptional divergence

Hagai, T.; Fraimovitch, E.

10.1101/2021.07.03.450995 — evolutionary biology — Posted on 2021-07-04

3578 Bark beetles locate fungal symbionts by detecting volatile fungal metabolites of host tree resin monoterpenes

Kandasamy, D.; Zaman, R.; Nakamura, Y.; Zhao, T.; Hartmann, H.; Andersson, M. N.; Hammerbacher, A.; Gershenzon, J.

10.1101/2021.07.03.450988 — ecology — Posted on 2021-07-04

3579 Invasive grass causes biotic homogenization in wetland birds

Robichaud, C.; Rooney, R. C.

10.1101/2021.07.03.451016 — ecology — Posted on 2021-07-04

3580 Impact of cilia-related genes on mitochondrial dynamics during Drosophila spermatogenesis

Bauerly, E.; Akiyama, T.; Yi, K.; Gibson, M.

10.1101/2021.07.03.450990 — developmental biology — Posted on 2021-07-04

3581 Primary cilia drive postnatal tidemark patterning in articular cartilage by coordinating responses to Indian Hedgehog and mechanical load

Rux, D.; Helbig, K.; Han, B.; Cortese, C.; Koyama, E.; Han, L.; Pacifici, M.

10.1101/2021.07.04.451018 — developmental biology — Posted on 2021-07-04

3582 Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation

Kang, J.; Pearson, R.; Zhu, H.; Chan, K. T.; Huang, X.; Blake, S.; Trigos, A. S.; Anderson, D.; Creek, D. J. S.; De Souza, D. P.; Wang, X.; Fu, C.; Jana, M.; Sanij, E.

10.1101/2021.07.04.451041 — cell biology — Posted on 2021-07-04

3583 Consistent changes in the intestinal microbiota of Atlantic salmon fed insect meal diets

Li, Y.; Gajardo, K.; Jaramillo-Torres, A.; Kortner, T. M.; Krogdahl, A.

10.1101/2021.07.04.451034 — microbiology — Posted on 2021-07-04

3584 Network-based identification and pharmacological targeting of host cell master regulators induced by SARS-CoV-2 infection

Laise, P.; Stanifer, M. L.; Bosker, G.; Sun, X.; Triana, S.; Doldan, P.; La Manna, F.; De Menna, M.; Realubit, R. B.; Pampou, S.; Karan, C.; Alexandrov, T.; Kruithof-de Julio, M.; Califano, A.; Boulant, S.; Alvarez, M. J.

10.1101/2021.07.03.451001 — microbiology — Posted on 2021-07-04

3585 Single-cell analysis uncovers differential regulation of lung γδ T cell subsets by the co-inhibitory molecules, PD-1 and TIM-3

Edwards, S. C.; Hedley, A.; Hoevenaar, W. H. M.; Glauner, T.; Wiesheu, R.; Kilbey, A.; Shaw, R.; Boufea, K.; Batada, N.; Blyth, K.; Miller, C.; Kirschner, K.; Coffelt, S. B.

10.1101/2021.07.04.451035 — immunology — Posted on 2021-07-04

3586 Neuronal activity drives pathway-specific depolarization of astrocyte distal processes

Armbruster, M.; Naskar, S.; Garcia, J.; Sommer, M.; Kim, E.; Adam, Y.; Haydon, P. G.; Boyden, E. S.; Cohen, A. E.; Dulla, C. G.

10.1101/2021.07.03.450922 — neuroscience — Posted on 2021-07-04

3587 Amyloid-β and tau pathologies relate to distinctive brain dysconnectomics in preclinical autosomal-dominant Alzheimer's disease

Guzman-Velez, E.; Diez, I.; Schoemaker, D.; Pardilla-Delgado, E.; Vila-Castelar, C.; Fox-Fuller, J. T.; Baena, A.; Sperling, R. A.; Johnson, K. A.; Lopera, F.; Sepulcre, J.; Quiroz, Y. T.

10.1101/2021.07.03.450933 — neuroscience — Posted on 2021-07-04

3588 Accelerating leaf area measurement using a volumetric approach

Haghshenas, A.; Emam, Y.

10.1101/2021.07.03.451015 — plant biology — Posted on 2021-07-04

3589 Close to optimal cell sensing ensures the robustness of tissue differentiation process: the avian photoreceptor mosaic case

Barua, A.; Beygi, A.; Hatzikirou, H.

10.1101/2021.02.14.431147 — biophysics — Posted on 2021-07-04

3590 Allotypic variation in antigen processing controls antigenic peptide generation from SARS-CoV-2 S1 Spike Glycoprotein

Stamatakis, G.; Samiotaki, M.; Temponeras, I.; Panayotou, G.; Stratikos, E.

10.1101/2021.07.03.450989 — biochemistry — Posted on 2021-07-04

3591 Behavioral performance requirements for division of labor influence adaptive brain mosaicism in a socially complex ant

Muratore, I. B.; Fandozzi, E. M.; Traniello, J. F. A.

10.1101/2021.07.03.450997 — animal behavior and cognition — Posted on 2021-07-04

3592 Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma

Freeman, S. S.; Sade-Feldman, M.; Kim, J.; Stewart, C.; Gonye, A. L. K.; Ravi, A.; Arniella, M. B.; Gushterova, I.; LaSalle, T. J.; Blaum, E. M.; Yizhak, K.; Frederick, D. T.; Sharova, T.; Leshchiner, I.; Elagina, L.; Spiro, O. G.; Livitz, D.; Rosebrock, D.; Aguet, F.; Carrot-Zhang, J.; Ha, G.; Lin, Z.; Chen, J. H.; Barzily-Rokni, M.; Hammond, M. R.; Vitzthum von Eckstaedt, H. C.; Blackmon, S. M.; Jiao, Y. J.; Gabriel, S.; Lawrence, D. P.; Duncan, L. M.; Stemmer-Rachamimov, A. O.; Wargo, J. A.; Flaherty, K. T.; Sullivan, R. J.; Boland, G. M.; Meyerson, M.; Getz, G.; Hacohen, N.

10.1101/2021.07.03.450733 — genomics — Posted on 2021-07-04

3593 A New Likelihood-based Test for Natural Selection

Simon, H. E.; Huttley, G. A.

10.1101/2021.07.04.451068 — genetics — Posted on 2021-07-04

3594 Detecting phylodiversity-dependent diviersification with a general phylogenetic inference framework

Richter, F.; Janzen, T.; Hildenbrandt, H.; Wit, E. C.; Etienne, R. S.

10.1101/2021.07.01.450729 — evolutionary biology — Posted on 2021-07-04

3595 Hot and sour: parasite adaptations to honey bee body temperature and pH

Palmer-Young, E. C.; Raffel, T. R.; Evans, J. D.

10.1101/2021.07.03.447385 — ecology — Posted on 2021-07-04

3596 Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes

Rai, A.; Liu, T.; Katrukha, E. A.; Estevez-Gallego, J.; Paterson, I.; Diaz, F.; Kapitein, L. C.; Moores, C. A.; Akhmanova, A.

10.1101/2021.02.11.430743 — cell biology — Posted on 2021-07-04

3597 Three-dimensional drug screen identifies HDAC inhibitors as therapeutic agents in mTORC1-driven lymphangioleiomyomatosis

Pietrobon, A.; Yockell-Lelievre, J.; Melong, N.; Smith, L. J.; Delaney, S. P.; Azzam, N.; Xue, C.; Merwin, N.; Lian, E.; Camacho-Magallanes, A.; Dore, C.; Musso, G.; Julian, L. M.; Kristof, A. S.; Tam, R. Y.; Berman, J. N.; Shoichet, M. S.; Stanford, W. L.

10.1101/2021.07.03.451004 — cell biology — Posted on 2021-07-04

3598 SARS-CoV-2 Nsp14 mediates the effects of viral infection on the host cell transcriptome

Zaffagni, M.; Harris, J. M.; Patop, I. L.; Pamudurti, N. R.; Nguyen, S.; Kadener, S.

10.1101/2021.07.02.450964 — molecular biology — Posted on 2021-07-04

3599 A multi-gene region targeted capture approach to detect plant DNA in environmental samples: A case study from coastal environments

Foster, N.; Van Dijk, K.-j.; Biffin, E.; Young, J.; Thomson, V. A.; Gillanders, B.; Jones, A.; Waycott, M.

10.1101/2021.07.03.450983 — molecular biology — Posted on 2021-07-04

3600 Enzymatic and structural characterization of HAD5, an essential phosphomannomutase of malaria parasites

Frasse, P. M.; Miller, J. J.; Soleimani, E.; Zhu, J.-S.; Jakeman, D. L.; Jez, J. M.; Goldberg, D. E.; Odom John, A. R.

10.1101/2021.07.03.451008 — microbiology — Posted on 2021-07-04

3601 Multivalency enhances the specificity of Fc-cytokine fusions

Orcutt-Jahns, B.; Emmel, P. C.; Snyder, E. M.; Posner, C.; Carlson, S. M.; Meyer, A. S.

10.1101/2021.07.03.451002 — immunology — Posted on 2021-07-04

3602 HAPPILEE: The Harvard Automated Processing Pipeline In Low Electrode Electroencephalography, a standardized software for low density EEG and ERP data

Lopez, K. L.; Monachino, A. D.; Morales, S.; Leach, S.; Bowers, M.; Gabard-Durnam, L. J.

10.1101/2021.07.02.450940 — neuroscience — Posted on 2021-07-04

3603 RAFFT: Efficient prediction of RNA folding pathways using the fast Fourier transform

opuu, v.; Nono Saha, C. M.; Smerlak, M.

10.1101/2021.07.02.450908 — bioinformatics — Posted on 2021-07-04

3604 3D printed lung on a chip device with a stretchable nanofibrous membrane for modeling ventilator induced lung injury

Tas, S.; Rehnberg, E.; Bölükbas, D. A.; Beech, J. P.; Nasi Kazado, L.; Svenningsson, I.; Arvidsson, M.; Sandberg, A.; Dahlgren, K. A.; Edthofer, A.; Gustafsson, A.; Isaksson, H.; Wood, J. A.; Tegenfeldt, J. O.; Wagner, D. E.

10.1101/2021.07.02.450873 — bioengineering — Posted on 2021-07-04

3605 Historical climate change and megafaunal extinctions linked to genetic diversity declines in shorebirds

Tan, H. Z.; Jansen, J. J. F. J.; Allport, G. A.; Garg, K. M.; Chattopadhyay, B.; Irestedt, M.; Chilton, G.; Gwee, C. Y.; Rheindt, F. E.

10.1101/2021.07.02.450884 — evolutionary biology — Posted on 2021-07-04

3606 An executive center for the intake of liquids

Dempsey, B.; Sungeelee, S.; Bokiniec, P.; Chettouh, Z.; Diem, S.; Autran, S.; Harrell, E. R.; Poulet, J. F. A.; Birchmeier, C.; Carey, H.; Genovesio, A.; McMullan, S.; Goridis, C.; Fortin, G.; Brunet, J.-F.

10.1101/2021.07.02.450862 — neuroscience — Posted on 2021-07-04

3607 Using Progressive Context Encoders for Anomaly Detection in Digital Pathology Images

Gillard, R.; Gu, Q.; Meroueh, C.; Prodduturi, N.; Patil, S.; Flotte, T. J.; Hart, S. N.

10.1101/2021.07.02.450957 — pathology — Posted on 2021-07-04

3608 Single cell tools for WormBase

da Veiga Beltrame, E.; Arnaboldi, V.; Sternberg, P. W.

10.1101/2021.07.04.451030 — bioinformatics — Posted on 2021-07-04

3609 Combining Attention-based Multiple Instance Learning and Gaussian Processes for CT Hemorrhage Detection

Wu, Y.; Schmidt, A.; Sanchez, E. H.; Molina, R.; Katsaggelos, A. K.

10.1101/2021.07.01.450539 — bioinformatics — Posted on 2021-07-04

3610 RNA modification mapping with JACUSA2

Piechotta, M.; Wang, Q.; Altmueller, J.; Dieterich, C.

10.1101/2021.07.02.450888 — bioinformatics — Posted on 2021-07-04

3611 A scalable, multi-wavelength, broad bandwidth frequency-domain near-infrared spectroscopy platform for real-time quantitative tissue optical imaging

Stillwell, R. A.; Kitsmiller, V. J.; Wei, A. Y.; Chong, A.; Senn, L.; O'Sullivan, T. D.

10.1101/2021.07.02.450969 — bioengineering — Posted on 2021-07-04

3612 Real-time monitoring of drug pharmacokinetics within tumor tissue in live animals

Seo, J.-W.; Fu, K.; Correa, S.; Eisenstein, M.; Appel, E. A.; Soh, H. T.

10.1101/2021.07.03.451023 — bioengineering — Posted on 2021-07-04

3613 A Novel Art of Electrocardiogram Assessment in Zebrafish for Cardiovascular Disease Studies and Drug Screening

Le, T.; Zhang, J.; Nguyen, A. H.; Trigo Torres, R. S.; Vo, K.; Dutt, N.; Lee, J.; Ding, Y.; Xu, X.; Lau, M. P. H.; Cao, H.

10.1101/2021.07.02.450921 — bioengineering — Posted on 2021-07-04

3614 Implicitly Learned Higher Order Associations Differentiates Recent and Remote Retrieval of Temporal Order Memory

Shridhar, S.; Singh, V.; Bhatt, R.; Kundu, S.; Jayaprakash, B.

10.1101/2021.07.03.451031 — animal behavior and cognition — Posted on 2021-07-04

3615 A genome-wide association study of serum proteins reveals shared loci with common diseases

Gudjonsson, A.; Gudmundsdottir, V.; Axelsson, G. T.; Gudmundsson, E. F.; Jonsson, B. G.; Launer, L. J.; Lamb, J. R.; Jennings, L. L.; Aspelund, T.; Emilsson, V.; Gudnason, V.

10.1101/2021.07.02.450858 — genomics — Posted on 2021-07-04

3616 Systems Biology Analysis of Human Genomes Points to Key Pathways Conferring Spina Bifida Risk

Aguiar-Pulido, V.; Wolujewicz, P.; Martinez-Fundichely, A.; Elhaik, E.; Thareja, G.; Abdel-Aleem, A.; Chalhoub, N.; Cuykendall, T.; Al-Zamer, J.; Lei, Y.; El-Bashir, H.; Musser, J. M.; Al-Kaabi, A.; Shaw, G. M.; Khurana, E.; Suhre, K.; Mason, C.; Elemento, O.; Finnell, R. H.; Ross, M. E.

10.1101/2021.07.02.450913 — genomics — Posted on 2021-07-04

3617 Economic costs of biological invasions in the United States

Fantle-Lepczyk, J.; Haubrock, P. J.; Cuthbert, R. N.; Kramer, A. M.; Turbelin, A. J.; Crystal-Ornelas, R.; Diagne, C.; Courchamp, F.

10.1101/2021.07.02.450757 — ecology — Posted on 2021-07-04

3618 Controlling Staphylococcus aureus by 2-phenol (2-MAMP) in a co-culture moderates the biofilm and virulence of Pseudomonas aeruginosa

Selvan, G. T.; Thirunavukkarasu, B.; Pravallika, N. N.; Vasudevan, S.; Palaniappan, B.; Solomon, A. P.

10.1101/2021.07.03.451022 — microbiology — Posted on 2021-07-04

3619 Single-domain antibodies for targeting, detection and in vivo imaging of human CD4+ cells

Traenkle, B.; Kaiser, P. D.; Pezzana, S.; Richardson, J.; Gramlich, M.; Wagner, T. R.; Weldle, M.; Holz, S.; Parfyonova, Y.; Schaller, M.; Nueske, S.; Scholz, A.; Zeck, A.; Jakobi, M.; Schneiderhan-Marra, N.; Maurer, A.; Gouttefangeas, C.; Kneilling, M.; Pichler, B. J.; Sonanini, D.; Rothbauer, U.

10.1101/2021.07.02.450848 — immunology — Posted on 2021-07-04

3620 Single nucleus transcriptomic analysis of human dorsal root ganglion neurons

Nguyen, M. Q.; von Buchholtz, L. J.; Reker, A. N.; Ryba, N. J. P.; Davidson, S.

10.1101/2021.07.02.450845 — neuroscience — Posted on 2021-07-04

3621 Deep learning the arrow of time in brain activity: characterising brain-environment behavioural interactions in health and disease

Deco, G. L.; Sanz Perl, Y.; Sitt, J.; Tagliazucchi, E.; Kringelbach, M. L.

10.1101/2021.07.02.450899 — neuroscience — Posted on 2021-07-04

3622 Single-orientation Quantitative Susceptibility Mapping identifies the Ventral Intermediate Nucleus of the Thalamus

Yu, F. F.; Lee, D.; Achilleos, M.; Feltrin, F.; Shah, B. R.

10.1101/2021.07.02.450973 — neuroscience — Posted on 2021-07-04

3623 Striatal role in everyday life and laboratory developed habits

Guida, P.; Michiels, M.; Redgrave, P.; Luque, D.; Obeso, I.

10.1101/2021.07.02.450904 — neuroscience — Posted on 2021-07-04

3624 A multimodal AI system for out-of-distribution generalization of seizure detection

Yang, Y.; Truong, N. D.; Eshraghian, J. K.; Maher, C.; Nikpour, A.; Kavehei, O.

10.1101/2021.07.02.450974 — neuroscience — Posted on 2021-07-04

3625 Healthcare experience disrupts representational similarity between one's and others' pain in anterior insula

Corradi-Dell'Acqua, C.; Hofstetter, C.; Sharvit, G.; Hugli, O.; Vuilleumier, P.

10.1101/2021.07.01.450687 — neuroscience — Posted on 2021-07-04

3626 Out of rhythm: Compromised precision of theta-gamma coupling impairs associative memory in old age

Karlsson, A. E.; Lindenberger, U.; Sander, M. C.

10.1101/2021.07.02.450954 — neuroscience — Posted on 2021-07-04

3627 The HAPPE plus Event-Related (HAPPE+ER) Software: A Standardized Processing Pipeline for Event-Related Potential Analyses

Monachino, A. D.; Lopez, K. L.; Pierce, L. J.; Gabard-durnam, l. J.

10.1101/2021.07.02.450946 — neuroscience — Posted on 2021-07-04

3628 Motif-centric phosphoproteomics to target kinase-mediated signaling pathways

Tsai, C.-F.; Ogata, K.; Sugiyama, N.; Ishihama, Y.

10.1101/2021.07.02.450911 — systems biology — Posted on 2021-07-04

3629 Making BrainWaves: Portable Brain Technologies in Biology Education

Davidesco, I.; Azeka, S.; Carter, S.; Laurent, E.; Valk, H.; Naipaul, J.; Dikker, S.; Suzuki, W. A.

10.1101/2021.07.02.450935 — scientific communication and education — Posted on 2021-07-04

3630 Fatty acid binding proteins shape the cellular response to activation of the glucocorticoid receptor

Liu, B.; Chandrashekaran, I. R.; Ilyichova, O.; Valour, D.; Melchiore, F.; Bourrier, C.; Giganti, A.; Stephan, J.-P.; Dacquet, C.; Genissel, P.; Gosgnach, W.; Weaver, R. J.; Porter, C. J.; Scanlon, M. J.; Halls, M. L.

10.1101/2021.07.02.450968 — pharmacology and toxicology — Posted on 2021-07-04

3631 The first observation of osmotically neutral sodium accumulation in the myocardial interstitium

Artyukov, I.; Arutyunov, G.; Bobrov, M. A.; Bukreeva, I.; Cedola, A.; Dragunov, D.; Feshchenko, R.; Fratini, M.; Mitrokhin, V. M.; Sokolova, A. V.; Vinogradov, A.; Gianoncelli, A.

10.1101/2021.07.02.450864 — biophysics — Posted on 2021-07-04

3632 Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket - Targeting P-pocket by fragment screening

Singh, A. K.; Martinez, S. E.; Gu, W.; Nguyen, H.; Schols, D.; Herdewijn, P. H.; De Jonghe, S.; Das, K.

10.1101/2021.07.03.451029 — biophysics — Posted on 2021-07-04

3633 phasebook: haplotype-aware de novo assembly of diploid genomes from long reads

Luo, X.; Kang, X.; Schoenhuth, A.

10.1101/2021.07.02.450883 — bioinformatics — Posted on 2021-07-04

3634 Strainline: full-length de novo viral haplotype reconstruction from noisy long reads

Luo, X.; Kang, X.; Schoenhuth, A.

10.1101/2021.07.02.450893 — bioinformatics — Posted on 2021-07-04

3635 APRILE: Exploring the Molecular Mechanisms of Drug Side Effects with Explainable Graph Neural Networks

Xu, H.; Sang, S.; Yao, H.; Herghelegiu, A. I.; Lu, H.; Yang, L.

10.1101/2021.07.02.450937 — bioinformatics — Posted on 2021-07-04

3636 The VersaLive platform enables pipette-compatible microfluidic mammalian cell culture for versatile applications

Nocera, G. M.; Viscido, G.; Brillante, S.; Carrella, S.; di Bernardo, D.

10.1101/2021.07.02.450869 — bioengineering — Posted on 2021-07-04

3637 Repopulation of a 3D-simulated periapical lesion cavity with triggered osteoblastic-differentiated dental pulp stem cell spheroids.

Ribeiro, V. L.; Dernowsek, J. A.; Fernandes, R. R.; Pitol, D.; Issa, J. P.; Chaves, J.; Bombonato-Prado, K. F.; Sousa-Neto, M. D.; Passos, G. A.

10.1101/2021.07.02.450930 — bioengineering — Posted on 2021-07-04

3638 Extrachromosomal DNA is associated with chromothripsis events and diverse prognoses in gastric cardia adenocarcinoma

Zhao, X.; Xing, P.; Song, X.; Zhao, M.; Zhao, L.; Dang, Y.; Lei, L.-L.; Xu, R.-H.; Han, W.-L.; Wang, P.-P.; Yang, M.-M.; Hu, J.-F.; Zhong, K.; Zhou, F.-Y.; Han, X.-N.; Meng, C.-L.; Ji, J.-J.; Chen, X.; Wang, L.-D.

10.1101/2021.07.02.450861 — genomics — Posted on 2021-07-04

3639 Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection

Brugger, M.; Demoulins, T.; Barut, G. T.; Zumkehr, B.; Oliveira Esteves, B.; Mehinagic, K.; Haas, Q.; Schogler, A.; Rameix-Welti, M.-A.; Eleouet, J.-F.; Moehrlen, U.; Marti, T.; Schmid, R.; Summerfield, A.; Posthaus, H.; Ruggli, N.; Hall, S.; Alves, M. P.

10.1101/2021.05.12.443770 — microbiology — Posted on 2021-07-04

3640 Reward and expectancy effects on neural signals of motor preparation and execution

Chen, X.-J.; van den Berg, B.; Kwak, Y.

10.1101/2021.07.02.450521 — neuroscience — Posted on 2021-07-04

3641 Structural basis for the specificity of PPM1H phosphatase for Rab GTPases

Waschbüsch, D.; Berndsen, K.; Lis, P.; Knebel, A.; Lam, Y. P.; Alessi, D. R.; Khan, A. R.

10.1101/2021.02.17.431620 — biochemistry — Posted on 2021-07-04

3642 A structural basis for inhibition of the complement initiator protease C1r by Lyme disease spirochetes

Garrigues, R. J.; Pierce, A. D. P.; Hammel, M.; Skare, J. T.; Garcia, B. L.

10.1101/2021.01.21.427683 — microbiology — Posted on 2021-07-04

3643 Extended Graphical Lasso for Multiple Interaction Networks for High Dimensional Omics Data

Xu, Y.; Jiang, H.; Jiang, W.

10.1101/2021.02.16.431400 — systems biology — Posted on 2021-07-04

3644 MAGI2-AS3 modulates proliferation, apoptosis and glycolysis in acute lymphoblastic leukemia via miR-452-5p/FOXN3 axis

Chen, X.-G.; Dou, B.-H.; An, J.-D.; Feng, S.; Liu, N.; Sheng, G.-Y.

10.1101/2021.07.02.450970 — cancer biology — Posted on 2021-07-04

3645 VPRBP functions downstream of the androgen receptor and OGT to restrict p53 activation in prostate cancer

Poulose, N.; Polonski, A.; Forsythe, N.; Gregg, G.; Maguire, S.; Fuchs, M.; Minner, S.; McDade, S. S.; Mills, I.

10.1101/2021.02.28.433236 — cancer biology — Posted on 2021-07-04

3646 Single caudate neurons encode temporally discounted value for formulating motivation for action

Hori, Y.; Mimura, K.; Nagai, Y.; Fujimoto, A.; Oyama, K.; Kikuchi, E.; Inoue, K.-i.; Takada, M.; Suhara, T.; Richmond, B. J.; Minamimoto, T.

10.1101/2020.05.18.101824 — neuroscience — Posted on 2021-07-04

3647 Epigenetic dynamics of centromeres and neocentromeres in Cryptococcus deuterogattii

Schotanus, K.; Yadav, V.; Heitman, J.

10.1101/2020.11.05.369892 — genetics — Posted on 2021-07-04

3648 Combinatorial Polyacrylamide Hydrogels for Preventing Biofouling on Implantable Biosensors

Chan, D.; Chien, J.-C.; Axpe, E.; Blankemeier, L.; Baker, S. W.; Swaminathan, S.; Piunova, V. A.; Zubarev, D. Y.; Maikawa, C. L.; Grosskopf, A. K.; Mann, J. L.; Soh, H. T.; Appel, E. A.

10.1101/2020.05.25.115675 — bioengineering — Posted on 2021-07-04

3649 Tfap2b specifies an embryonic melanocyte stem cell population that retains adult multi-fate potential

Brombin, A.; Simpson, D. J.; Travnickova, J.; Brunsdon, H. R.; Zeng, Z.; Lu, Y.; Chandra, T.; Patton, E. E.

10.1101/2021.06.18.448859 — developmental biology — Posted on 2021-07-04

3650 Gymnasts' ability to modulate bioelectric sensorimotor rhythms during kinesthetic motor imagery of sports non-specific movements

Sugino, H.; Ushiyama, J.

10.1101/2021.05.17.444451 — neuroscience — Posted on 2021-07-04

3651 Gradient-mixing LEGO robots for purifying DNA origami nanostructures of multiple components by rate-zonal centrifugation

Sentosa, J.; Horne, B.; Djutanta, F.; Showkeir, D.; Rezvani, R.; Hariadi, R. F.

10.1101/2021.07.02.450731 — biophysics — Posted on 2021-07-04

3652 Computational identification of splicing phenotypes from single cell transcriptomic experiments

Huang, Y.; Sanguinetti, G.

10.1101/2020.11.04.368019 — bioinformatics — Posted on 2021-07-04

3653 Rethinking habitat occupancy modeling and the role of diel activity in an anthropogenic world

Rivera, K.; Fidino, M.; Farris, Z.; Magle, S.; Murphy, A.; Gerber, B.

10.1101/2021.06.30.450589 — ecology — Posted on 2021-07-03

3654 The endoplasmic reticulum-resident protein TMEM-120/TMEM120A promotes fat storage in C. elegans and mammalian cells

Li, Y.; Huang, S.; Li, X.; Yang, X.; Xu, N.; Qu, J.; Mak, H. Y.

10.1101/2021.06.29.450322 — cell biology — Posted on 2021-07-04

3655 Odor-evoked Increases in Olfactory Bulb Mitral Cell Spiking Variability

Ly, C.; Barreiro, A. K.; Gautam, S. H.; Shew, W. L.

10.1101/2021.03.05.434131 — neuroscience — Posted on 2021-07-03

3656 MEG, myself, and I: individual identification from neurophysiological brain activity

da Silva Castanheira, J.; Orozco, H. D.; Misic, B.; Baillet, S.

10.1101/2021.02.18.431803 — neuroscience — Posted on 2021-07-03

3657 Parallel processing in speech perception: Local and global representations of linguistic context

Brodbeck, C.; Bhattasali, S.; Cruz Heredia, A. A. L.; Resnik, P.; Simon, J. Z.; Lau, E.

10.1101/2021.07.03.450698 — neuroscience — Posted on 2021-07-03

3658 Deep learning and cross-species analysis identify the influences of sex and cannabinoidsignaling on cerebellar vermis morphology

Black, K. C.; McPherson, B. C.; Hainline, J.; Baygani, S.; Webb, B.; Mier, T. J.; Essex, A.; Mackie, K.; Pestilli, F.; Kalinovsky, A.

10.1101/2021.07.03.450642 — neuroscience — Posted on 2021-07-03

3659 The role of feedback in the production of skilled finger sequences

Popp, N. J.; Hernandez-Castillo, C. R.; Gribble, P. L.; Diedrichsen, J.

10.1101/2021.07.02.450916 — neuroscience — Posted on 2021-07-03

3660 Music-Based Intervention Connects Auditory and Reward Systems

Quinci, M.; Belden, A.; Goutama, V.; Gong, D.; Hanser, S.; Donovan, N. J.; Geddes, M.; Loui, P.

10.1101/2021.07.02.450867 — neuroscience — Posted on 2021-07-03

3661 mGluR5 Negative Modulators for Fragile X: Resistance and Persistence

Stoppel, D. C.; McCamphill, P. K.; Senter, R. K.; Heynen, A. J.; Bear, M. F.

10.1101/2021.07.02.450894 — neuroscience — Posted on 2021-07-03

3662 Hyperdirect connectivity of opercular speech network to the subthalamic nucleus

Jorge, A.; Lipksi, W. J.; Wang, D.; Crammond, D. J.; Turner, R. S.; Richardson, R. M.

10.1101/2021.07.02.450909 — neuroscience — Posted on 2021-07-04

3663 Corticosterone differentially modulates time-dependent fear generalization following mild or moderate fear conditioning training in rats

dos Santos Correa, M.; Vaz, B. d. S.; Menezes, B. S.; Ferreira, T. L.; Tiba, P. A.; Fornari, R. V.

10.1101/2021.03.10.434749 — animal behavior and cognition — Posted on 2021-07-03

3664 Genomic evolution of the globally disseminated multidrug-resistant Klebsiella pneumoniae clonal group 147

Rodrigues, C.; Desai, S.; Passet, V.; Gajjar, D.; Brisse, S.

10.1101/2021.07.03.450759 — genomics — Posted on 2021-07-03

3665 Decay and damage of therapeutic phage OMKO1 by environmental stressors

Blazanin, M.; Lam, W. T.; Vasen, E.; Chan, B. K.; Turner, P.

10.1101/864025 — microbiology — Posted on 2021-07-03

3666 Complement C3 and C3aR mediate different aspects of emotional behaviours; relevance to risk for psychiatric disorder

Westacott, L. J.; Humby, T.; Naan, N.; Brain, S. A.; Bush, E.-L.; Toneva, M.; Baloc, A.-I.; Moon, A. L.; Reddaway, J.; Owen, M. J.; Hall, J.; Hughes, T. R.; Morgan, B. P.; Gray, W. P.; Wilkinson, L.

10.1101/685537 — neuroscience — Posted on 2021-07-03

3667 Comparative Analysis of non-coding small-RNAs in P. aeruginosa Keratitis Strains with Different Antibiotic Susceptibility

Kandasamy, K.; Devarajan, B.

10.1101/2021.07.02.450871 — genomics — Posted on 2021-07-03

3668 Entorhinal cortex EWAS meta-analysis highlights four novel loci showing differential methylation in Alzheimer's disease

Sommerer, Y.; Dobricic, V.; Schilling, M.; Ohlei, O.; Sabet, S. S.; Wesse, T.; Fuss, J.; Franzenburg, S.; Franke, A.; Parkkinen, L.; Lill, C. M.; Bertram, L.

10.1101/2021.07.02.450878 — genomics — Posted on 2021-07-03

3669 Reduced representation sequencing to understand the evolutionary history of Torrey pine (Pinus torreyana Parry) with implications for rare species conservation

Di Santo, L. N.; Hoban, S.; Parchman, T. L.; Wright, J. W.; Hamilton, J. A.

10.1101/2021.07.02.450939 — genomics — Posted on 2021-07-03

3670 Discovery of UPSTREAM OF FLOWERING LOCUS C (UFC) and FLOWERING LOCUS C EXPRESSOR (FLX) in Gladiolus xhybridus, G. dalenii

Aljaser, J.; Anderson, N. O.; Noyszewski, A.

10.1101/2021.07.02.450944 — genetics — Posted on 2021-07-03

3671 The blood vasculature instructs lymphatics patterning in a SOX7-dependent manner

Chiang, I. K. N.; Luu, W.; Jiang, K.; Kirschnick, N.; Moustaqil, M.; Davidson, T. L.; Lesieur, E.; Skoczylas, R.; Kouskoff, V.; Kazenwadel, J.; Arriola-Martinez, L.; Sierecki, E.; Gambin, Y.; Alitalo, K.; Kiefer, F.; Harvey, N. L.; Francois, M.

10.1101/2021.07.02.450967 — developmental biology — Posted on 2021-07-03

3672 ERp44 is Required for Endocardial Cushion Development by Regulating VEGFA Secretion in Myocardium

Bi, Y.; Yang, Z.; Jin, M.; Zhai, K.; Wang, J.; Mao, Y.; Liu, Y.; Ding, M.; Wang, H.; Wang, F.; Ji, G.

10.1101/2021.07.02.450976 — developmental biology — Posted on 2021-07-03

3673 PARP Inhibition Impedes the Maturation of Nascent DNA Strands During DNA Replication

Vaitsiankova, A.; Burdova, K.; Hanzlikova, H.; Caldecott, K.

10.1101/2021.07.03.450982 — cell biology — Posted on 2021-07-03

3674 Mammalian UPF3A and UPF3B activate NMD independently of their EJC binding

Yi, Z.; Arvola, R. M.; Myers, S.; Dilsavor, C. N.; Abu Alhasan, R.; Carter, B. N.; Patton, R. D.; Bundschuh, R.; Singh, G.

10.1101/2021.07.02.450872 — molecular biology — Posted on 2021-07-03

3675 Manual resolution of virome dark matter uncovers hundreds of viral families in the infant gut

Shah, S. A.; Deng, L.; Thorsen, J.; Pedersen, A. G.; Dion, M. B.; Castro Mejia, J.; Silins, R.; Romme, F. O.; Sausset, R.; Ndela, E. O.; Hjemso, M. H.; Rasmussen, M. A. A.; Redgwell, T.; Vestergaard, G. A.; Zhang, Y.; Enault, F.; Sorensen, S. J.; Bisgaard, H.; Stokholm, J.; Moineau, S.; Petit, M.-A.; Nielsen, D. S.

10.1101/2021.07.02.450849 — microbiology — Posted on 2021-07-03

3676 Identification of effector metabolites using exometabolite profiling of diverse microalgae

Brisson, V.; Mayali, X.; Bowen, B.; Golini, A.; Thelen, M. P.; Stuart, R. K.; Northen, T.

10.1101/2021.07.02.450979 — microbiology — Posted on 2021-07-03

3677 Plasmodium falciparum GBP2 is a telomere-associated protein that binds to G-quadruplex DNA and RNA

Edwards-Smallbone, J.; Jensen, A. L.; Roberts, L. E.; Totanes, F. I. G.; Hart, S. R.; Merrick, C. J.

10.1101/2021.07.02.450898 — microbiology — Posted on 2021-07-03

3678 Kinetic Properties of Microbial Exoenzymes Vary with Soil Depth but Have Similar Temperature Sensitivities Through the Soil Profile

Alves, R. J. E.; Callejas, I. A.; Marschmann, G. L.; Mooshammer, M.; Singh, H. W.; Whitney, B.; Torn, M. S.; Brodie, E. L.

10.1101/2021.07.02.450965 — microbiology — Posted on 2021-07-03

3679 Novel canine high-quality metagenome-assembled genomes, prophages, and host-associated plasmids by long-read metagenomics together with Hi-C proximity ligation

Cusco, A.; Perez, D.; Vines, J.; Fabregas, N.; Francino, O.

10.1101/2021.07.02.450895 — microbiology — Posted on 2021-07-03

3680 Evolutionary divergence of the Wsp signal transduction system in β- and γ-proteobacteria

Kessler, C.; Mhatre, E.; Cooper, V. S.; Kim, W.

10.1101/2021.07.02.450980 — microbiology — Posted on 2021-07-03

3681 Signatures of rapid synaptic learning in the hippocampus during novel experiences

Priestley, J. B.; Bowler, J. C.; Rolotti, S. V.; Fusi, S.; Losonczy, A.

10.1101/2021.07.02.450956 — neuroscience — Posted on 2021-07-03

3682 Pharmacokinetics and Central Accumulation of Delta-9-Tetrahydrocannabinol (THC) and its Bioactive Metabolites are Influenced by Route of Administration and Sex

Baglot, S. L.; Hume, C.; Petrie, G. N.; Aukema, R. J.; Lightfoot, S. H.; Grace, L. M.; Zhou, R.; Parker, L.; Rho, J. M.; Borgland, S. L.; McLaughlin, R. J.; Brechenmacher, L.; Hill, M. N.

10.1101/2021.07.02.450963 — neuroscience — Posted on 2021-07-03

3683 The MAP3Ks DLK and LZK direct diverse responses to axon damage in zebrafish peripheral neurons

Adula, K. P.; Shorey, M.; Chauhan, V.; Nassman, K.; Chen, S.-F.; Rolls, M.; Sagasti, A.

10.1101/2021.07.03.450951 — neuroscience — Posted on 2021-07-03

3684 Atherosis of trophoblast type: A specific form of decidual vasculopathy distinct from atherosis of macrophage type

Zhang, P.

10.1101/2021.07.02.450868 — pathology — Posted on 2021-07-03

3685 Monitoring the 5`UTR landscape reveals 5`terminal oligopyrimidine (TOP) motif switches to drive translational efficiencies

Weber, R.; Ghoshdastider, U.; Spies, D.; Dure, C.; Valdivia-Francia, F.; Forny, M.; Ormiston, M.; Renz, P. F.; Taborsky, D.; Yigit, M.; Yamahachi, H.; Sendoel, A.

10.1101/2021.07.02.450886 — cancer biology — Posted on 2021-07-03

3686 Truncation of IFT80 causes early embryonic loss in cattle

Obando Ortega, M. S.; Bickhart, D. M.; Clark, K. N.; Null, D. J.; Hutchison, J. L.; McClure, J. C.; Cole, J. B.

10.1101/2021.07.02.450952 — genomics — Posted on 2021-07-03

3687 Experimental and Bioinformatic upgrade for genome-wide mapping of nucleosomes in Trypanosoma cruzi

Beati, P.; Massimino Stepnicka, M.; Vilchez Larrea, S.; Alonso, G. D.; Ocampo, J.

10.1101/2021.07.02.450927 — genomics — Posted on 2021-07-03

3688 ENDO-Pore: High-throughput linked-end mapping of single DNA cleavage events using nanopore sequencing

Torres Montaguth, O. E.; Cross, S. J.; Ingram, K. W. A.; Lee, L.; Diffin, F. M.; Szczelkun, M.

10.1101/2021.07.02.450912 — molecular biology — Posted on 2021-07-03

3689 Identification of novel translated small ORFs in Escherichia coli using complementary ribosome profiling approaches

Stringer, A. M.; Smith, C.; Mangano, K.; Wade, J. T.

10.1101/2021.07.02.450978 — microbiology — Posted on 2021-07-03

3690 A Population-level Strain Genotyping Method to Study Pathogen Strain Dynamics in Human Infections

Morgan, S. J.; Durfey, S. L.; Ravishankar, S.; Jorth, P.; Ni, W.; Skerrett, D.; Aitken, M. L.; Mckone, E. F.; Salipante, S.; Radey, M.; Singh, P. K.

10.1101/2021.07.02.450905 — microbiology — Posted on 2021-07-03

3691 Plakoglobin and HMGB1 mediate intestinal epithelial cell apoptosis induced by Clostridioides difficile TcdB

Li, Y.; Xu, W.; Ren, Y.; Cheung, H.-C.; Huang, P.; Kaur, G.; Kuo, C.-J.; McDonough, S. P.; Fubini, S. L.; Lipkin, S. M.; Deng, X.; Chang, Y.-F.; Huang, L.

10.1101/2021.07.02.450318 — microbiology — Posted on 2021-07-03

3692 SARS-CoV-2 Lambda Variant Remains Susceptible to Neutralization by mRNA Vaccine-elicited Antibodies and Convalescent Serum

Tada, T.; Zhou, H.; Dcosta, B. M.; Samanovic, M. I.; Mulligan, M. J.; Landau, N. R.

10.1101/2021.07.02.450959 — immunology — Posted on 2021-07-03

3693 Mitochondrial dysfunction triggers secretion of the immunosuppressive factor α-fetoprotein

Jett, K. A.; Baker, Z. N.; Hossain, A.; Boulet, A.; Cobine, P. A.; Ghosh, S.; Ng, P.; Yilmaz, O.; Barretto, K.; DeCoteau, J.; Mochoruk, K.; Ioannou, G.; Savard, C.; Yuan, S.; Lowden, C.; Kim, B.-E.; Cheng, H.-Y. M.; Battersby, B. J.; Gohil, V. M. M.; Leary, S. C.

10.1101/2021.07.02.450924 — cell biology — Posted on 2021-07-03

3694 Dasabuvir inhibits human norovirus infection in human intestinal enteroids

Hayashi, T.; Murakami, K.; Hirano, J.; Fujii, Y.; Yamaoka, Y.; Ohashi, H.; Watashi, K.; Estes, M. K.; Muramatsu, M.

10.1101/2021.07.02.450857 — microbiology — Posted on 2021-07-03

3695 The pore conformation of lymphocyte perforin

Ivanova, M.; Lukoyanova, N.; Malhotra, S.; Topf, M.; Trapani, J. A.; Voskoboinik, I.; Saibil, H. R.

10.1101/2021.07.03.450947 — biochemistry — Posted on 2021-07-03

3696 Accurately positioning functional residues with robotics-inspired computational protein design

Krivacic, C.; Kundert, K.; Pan, X.; Pache, R. A.; Liu, L.; O Conchuir, S.; Jeliazkov, J. R.; Gray, J. J.; Thompson, M. C.; Fraser, J. S.; Kortemme, T.

10.1101/2021.07.02.450934 — bioengineering — Posted on 2021-07-03

3697 Benchmarking ideal sample thickness in cryo-EM using MicroED

Martynowycz, M. W.; Clabbers, M. T. B.; Unge, J.; Hattne, J.; Gonen, T.

10.1101/2021.07.02.450941 — biochemistry — Posted on 2021-07-03

3698 Why amyloid fibrils have a limited width

Boyer, D. R.; Mynhier, N. A.; Sawaya, M. R.

10.1101/2021.07.02.450971 — biochemistry — Posted on 2021-07-03

3699 Protein flexibility and dissociation pathway differentiation can explain onset of resistance mutations in kinases

Shekhar, M.; Smith, Z.; Seeliger, M.; Tiwary, P.

10.1101/2021.07.02.450932 — biochemistry — Posted on 2021-07-03

3700 Protein abundance and folding rather than the redox state of Kelch13 determine the artemisinin susceptibility of Plasmodium falciparum

Schumann, R.; Bischoff, E.; Klaus, S.; Möhring, S.; Flock, J.; Keller, S.; Remans, K.; Ganter, M.; Deponte, M.

10.1101/2021.07.02.450839 — biochemistry — Posted on 2021-07-03

3701 Exploring the Interactome of Cytochrome P450 2E1 in Human Liver Microsomes with Chemical Cross-Linking Mass Spectrometry

Davydov, D. R.; Dangi, B.; Yue, G.; Prasad, B.; Zgoda, V. G.

10.1101/2021.07.02.450960 — biochemistry — Posted on 2021-07-03

3702 Dissociation of β2m from MHC Class I Triggers Formation of Noncovalent, Transient Heavy Chain Dimers

Dirscherl, C.; Loechte, S.; Hein, Z.; Kopicki, J.-D.; Harders, A. R.; Linden, N.; Weghuber, J.; Garcia-Alai, M.; Uetrecht, C.; Zacharias, M.; Piehler, J.; Lanzerstorfer, P.; Springer, S.

10.1101/2021.07.02.450866 — cell biology — Posted on 2021-07-03

3703 Recruitment of Peroxin14 to lipid droplets affects triglyceride storage in Drosophila

Anderson-Baron, M.; Ueda, K.; Haskins, J.; Hughes, S. C.; Simmonds, A.

10.1101/2021.07.02.450950 — cell biology — Posted on 2021-07-03

3704 Erythroid differentiation in mouse erythroleukemia cells is driven via actin filament-tropomodulin3-tropomyosin networks

Ghosh, A.; Coffin, M.; West, R.; Fowler, V. M.

10.1101/2021.07.02.448760 — cell biology — Posted on 2021-07-03

3705 Integrated light and electron microscopy continuum resolution imaging of 3D cell cultures

Dimprima, E.; Garcia Montero, M.; Gawrzak, S.; Ronchi, P.; Zagoriy, I.; Schwab, Y.; Jechlinger, M.; Mahamid, J.

10.1101/2021.07.02.450855 — cell biology — Posted on 2021-07-03

3706 Biochemical and subcellular characterization of a squid hnRNPA/B-like protein in osmotic stress activated cells reflects molecular properties conserved in this protein family

Lopes, G.; Lico, D.

10.1101/2021.07.02.450876 — cell biology — Posted on 2021-07-03

3707 The number of cytokinesis nodes in mitotic fission yeast scales with cell volume

Sayyad, W. A.; Pollard, T. D.

10.1101/2021.07.02.450929 — cell biology — Posted on 2021-07-03

3708 Allergy-induced systemic inflammation impairs tendon quality

Lehner, C.; Spitzer, G.; Langthaler, P.; Jakubecova, D.; Klein, B.; Weissenbacher, N.; Wagner, A.; Gehwolf, R.; Trinka, E.; Iglseder, B.; Paulweber, B.; Aigner, L.; Couillard-Despres, S.; Weiss, R.; Tempfer, H.; Traweger, A.

10.1101/2021.07.02.450910 — molecular biology — Posted on 2021-07-03

3709 Development and Validation of a High-throughput Short Sequence Typing Scheme for Serratia marcescens Pure Culture and Environmental DNA

Bourdin, T.; Monnier, A.; Benoit, M.-E.; Bedard, E.; Prevost, M.; Quach, C.; Deziel, E.; Constant, P.

10.1101/2021.07.01.450819 — molecular biology — Posted on 2021-07-03

3710 Co-deletion of ATAD1 with PTEN primes cells for BIM-mediated apoptosis

Winter, J. M.; Fresenius, H. L.; Keys, H. R.; Cunningham, C. N.; Ryan, J.; Sirohi, D.; Berg, J. A.; Tripp, S. R.; Barta, P.; Agarwal, N.; Letai, A.; Sabatini, D. M.; Wohlever, M. L.; Rutter, J.

10.1101/2021.07.01.450781 — cancer biology — Posted on 2021-07-03

3711 Blockade of pro-fibrotic response mediated by the miR-143/-145 cluster prevents targeted therapy-induced phenotypic plasticity and resistance in melanoma

Diazzi, S.; Baeri, A.; Fassy, J.; Lecacheur, M.; Marin-Bejar, O.; Girard, C.; Lefevre, L.; Lacoux, C.; Irondelle, M.; Mounier, C.; Truchi, M.; Couralet, M.; Carminati, A.; Berestjuk, I.; Larbret, F.; Vassaux, G.; Marine, J.-C.; Deckert, M.; Mari, B.; Tartare-Deckert, S.

10.1101/2021.07.02.450838 — cancer biology — Posted on 2021-07-03

3712 Deep learning-based quantification of arbuscular mycorrhizal fungi in plant roots

Evangelisti, E.; Turner, C.; McDowell, A.; Shenhav, L.; Yunusov, T.; Gavrin, A.; Servante, E. K.; Quan, C.; Schornack, S.

10.1101/2021.03.05.434067 — plant biology — Posted on 2021-07-03

3713 Correlated Evolution in the Small Parsimony Framework

Smith, B.; Navarro-Martinez, C.; Buonopane, R.; Byun, A. S.; Patterson, M. D.

10.1101/2021.01.26.428213 — evolutionary biology — Posted on 2021-07-03

3714 A role for worm cutl-24 in background- and parent-of-origin-dependent ER stress resistance

Wang, W.; Flury, A.; Garrison, J.; Brem, R. B.

10.1101/2021.07.01.450736 — genetics — Posted on 2021-07-03

3715 Local thermal environment and warming influence supercooling and drive widespread shifts in the metabolome of diapausing Pieris rapae butterflies

Mikucki, E. E.; Lockwood, B. L.

10.1101/2020.06.29.178087 — evolutionary biology — Posted on 2021-07-03

3716 Density of Pied Crows Corvus albus in two of South Africa's protected areas

Johnson, T. F.; Murn, C.

10.1101/2021.05.19.444802 — ecology — Posted on 2021-07-03

3717 Glucose-dependent miR-125b is a negative regulator of β-cell function

Cheung, R. W. S.; Pizza, G.; Chabosseau, P.; Rolando, D.; Tomas, A.; Burgoyne, T.; Salowka, A.; Macklin, A.; Cao, Y.; Nguyen-Tu, M.-S.; Marchetti, P.; Shapiro, J.; Piemonti, L.; de Koning, E. J. P.; Leclerc, I.; Sakamoto, K.; Smith, D. M.; Rutter, G. A.; Martinez-sanchez, A.

10.1101/2021.05.17.444559 — molecular biology — Posted on 2021-07-03

3718 Modeling site-specific nucleotide biases affecting Himar1 transposon insertion frequencies in TnSeq datasets

Choudhery, S.; Brown, A. J.; Akusobi, C. D.; Rubin, E. J.; Sassetti, C. M.; Ioerger, T. R.

10.1101/2021.07.01.450749 — microbiology — Posted on 2021-07-03

3719 High-density transposon mutagenesis in Mycobacterium abscessus identifies an essential penicillin-binding lipo-protein (PBP-lipo) involved in septal peptidoglycan synthesis and antibiotic sensitivity

Akusobi, C.; Benghomari, B. S.; Wolf, I. D.; Singhvi, S.; Zhu, J.; Dulberger, C. L.; Ioerger, T. R.; Rubin, E. J.

10.1101/2021.07.01.450732 — microbiology — Posted on 2021-07-03

3720 A centronuclear myopathy-causing mutation in dynamin-2 perturbs the actin-dependent structure of dendritic spines leading to excitatory synaptic defects in a murine model of the disease

ARRIAGADA-DIAZ, J.; Gomez, B.; Prado-Vega, L.; MATTAR-ARAOS, M.; LABRANA-ALLENDE, M.; HINOSTROZA, F.; Gajardo, I.; Guerra-Fernandez, M. J.; Bevilacqua, J. A.; CARDENAS, A. M.; Bitoun, M.; ARDILES, A. O.; GONZALEZ-JAMETT, A. M.

10.1101/2021.06.28.450172 — neuroscience — Posted on 2021-07-03

3721 How does the brain represent the semantic content of an image?

Xu, H.; Liu, M.; Zhang, D.

10.1101/2021.06.23.449677 — neuroscience — Posted on 2021-07-03

3722 Directly interfacing brain and deep networks exposes non-hierarchical visual processing

Sexton, N. J.; Love, B. C.

10.1101/2021.06.28.450213 — neuroscience — Posted on 2021-07-03

3723 Structural connectome quantifies tumor invasion and predicts survival in glioblastoma patients

Wei, Y.; Li, C.; Cui, Z.; Mayrand, R. C.; Zou, J.; Wong, A. L. K. C.; Sinha, R.; Matys, T.; Schönlieb, C.-B.; Price, S. J.

10.1101/2021.03.09.434656 — neuroscience — Posted on 2021-07-03

3724 Water levels primarily drive variation in photosynthesis and nutrient use of scrub Red Mangroves in the southeastern Florida Everglades

Hogan, J. A.; Castaneda-Moya, E.; Lamb-Wotton, L.; Troxler, T.; Baraloto, C.

10.1101/2021.01.27.428494 — plant biology — Posted on 2021-07-03

3725 The Phtheirospermum japonicum isopentenyltransferase PjIPT1a regulates host cytokinin responses in Arabidopsis

Greifenhagen, A.; Braunstein, I.; Pfannstiel, J.; Yoshida, S.; Shirasu, K.; Schaller, A.; Spallek, T.

10.1101/2021.05.24.445531 — plant biology — Posted on 2021-07-03

3726 Gasdermin D mediates inflammation-induced defects in reverse cholesterol transport and promotes atherosclerosis.

Opoku, E.; Traughber, C. A.; Zhang, D.; Iacano, A. J.; Khan, M.; Han, J.; Smith, J. D.; Gulshan, K.

10.1101/2021.04.16.440183 — pathology — Posted on 2021-07-03

3727 Drosophila larval models of invasive tumourigenesis for in vivo studies on tumour/peripheral host tissue interactions during cancer cachexia.

Hodgson, J. A.; Parvy, J. P.; Yu, Y.; Vidal, M.; Cordero, J.

10.1101/2021.07.01.450696 — cancer biology — Posted on 2021-07-03

3728 KOMB: Graph-Based Characterization of Genome Dynamics in Microbial Communities

Balaji, A.; Sapoval, N.; Seto, C.; Elworth, R. A. L.; Nute, M. G.; Savidge, T.; Segarra, S.; Treangen, T. J.

10.1101/2020.05.21.109587 — bioinformatics — Posted on 2021-07-03

3729 SPOT-Contact-Single: Improving Single-Sequence-Based Prediction of Protein Contact Map using a Transformer Language Model

Singh, J.; Litfin, T.; Singh, J.; Paliwal, K.; Zhou, Y.

10.1101/2021.06.19.449089 — bioinformatics — Posted on 2021-07-03

3730 Protein-protein docking with large-scale backbone flexibility using coarse-grained Monte-Carlo simulations

Kurcinski, M.; Kmiecik, S.; Zalewski, M.; Kolinski, A.

10.1101/2021.02.22.432196 — bioinformatics — Posted on 2021-07-03

3731 Permutation-based significance analysis reduces the type 1 error rate in bisulfite sequencing data analysis of human umbilical cord blood samples

Laajala, E.; Halla-aho, V.; Grönroos, T.; Ullah, U.; Vähä-Mäkilä, M.; Nurmio, M.; Kallionpää, H.; Lietzen, N.; Mykkänen, J.; Rasool, O.; Toppari, J.; Oresic, M.; Knip, M.; Lund, R. J.; Lahesmaa, R.; Lähdesmäki, H.

10.1101/2021.05.18.444359 — bioinformatics — Posted on 2021-07-03

3732 Enhancing the interoperability of glycan data flow between ChEBI, PubChem, and GlyGen.

Navelkar, R.; Owen, G.; Mutherkrishnan, V.; Thiessen, P.; Bolton, E.; Cheng, T.; Edwards, N.; Tiemeyer, M.; Campbell, M.; Martin, M.; Vora, J.; Kahsay, R.; Mazumder, R.

10.1101/2021.06.17.448729 — bioinformatics — Posted on 2021-07-03

3733 Suppression of sost/sclerostin and dickkopf-1 promote intervertebral disc structure in mice

Kroon, T. M.; Niziolek, P.; Edwards, D.; Clinkenbeard, E. L.; Robling, A. G.; Holguin, N.

10.1101/2021.07.01.449486 — bioengineering — Posted on 2021-07-03

3734 Bayesian calibration, process modeling and uncertainty quantification in biotechnology

Helleckes, L. M.; Osthege, M.; Wiechert, W.; von Lieres, E.; Oldiges, M.

10.1101/2021.06.30.450546 — bioengineering — Posted on 2021-07-03

3735 Control over patch encounters changes foraging behaviour

Hall-McMaster, S.; Dayan, P.; Schuck, N. W.

10.1101/2021.01.19.426950 — animal behavior and cognition — Posted on 2021-07-03

3736 Convergent consequences of parthenogenesis on stick insect genomes

Jaron, K. S.; Parker, D. J.; Anselmetti, Y.; Tran Van, P.; Bast, J.; Dumas, Z.; Figuet, E.; Francois, C. M.; Hayward, K.; Rossier, V.; Simion, P.; Robinson-Rechavi, M.; Galtier, N.; Schwander, T.

10.1101/2020.11.20.391540 — evolutionary biology — Posted on 2021-07-03

3737 Environmental transmission of Pseudogymnoascus destructans to hibernating little brown bats

Hicks, A. C.; Darling, S.; Flewelling, J.; von Linden, R.; Meteyer, C. U.; Redell, D.; White, J. P.; Redell, J.; Smith, R.; Blehert, D.; Rayman, N.; Hoyt, J. R.; Okoniewski, J. C.; Langwig, K. E.

10.1101/2021.07.01.450774 — ecology — Posted on 2021-07-03

3738 Co-option of local and systemic immune responses by the hormonal signalling system triggering metamorphosis

Nunes, C.; Koyama, T.; Sucena, E.

10.1101/2021.05.22.444626 — developmental biology — Posted on 2021-07-03

3739 Self-Supervised Deep-Learning Encodes High-Resolution Features of Protein Subcellular Localization

Kobayashi, H.; Cheveralls, K. C.; Leonetti, M.; Royer, L. A.

10.1101/2021.03.29.437595 — cell biology — Posted on 2021-07-03

3740 The evolutionary origins of extreme halophilic Archaea

Feng, Y.; Neri, U.; Gosselin, S.; Louyakis, A. S.; Papke, R. T.; Gophna, U.; Gogarten, J. P.

10.1101/2019.12.19.883488 — microbiology — Posted on 2021-07-03

3741 Combined protein and transcript single cell RNA sequencing in human peripheral blood mononuclear cells

Vallejo, J.; Saigusa, R.; Gulati, R.; Ghosheh, Y.; Durant, C. P.; Roy, P.; Ehinger, E.; Pattarabanjird, T.; Padgett, L. E.; Olingy, C. E.; Hanna, D. B.; Landay, A. L.; Tracy, R. P.; Lazar, J. M.; Mack, W. J.; Weber, K. M.; Adimora, A. A.; Hodis, H. N.; Tien, P. C.; Ofotokun, I.; Heath, S. L.; Dinh, H. Q.; Shemesh, A.; McNamara, C. A.; Lanier, L. L.; Hedrick, C. C.; Kaplan, R. C.; Ley, K.

10.1101/2020.09.10.292086 — immunology — Posted on 2021-07-03

3742 The Role of the Human Brain Neuron-Glia-Synaptic Composition in Forming Resting State Functional Connectivity Networks

Kahali, S.; Raichle, M. E.; Yablonskiy, D. A.

10.1101/2021.07.01.449170 — neuroscience — Posted on 2021-07-03

3743 Behavioral and fMRI evidence that arousal enhances bottom-up attention and memory selectivity in young but not older adults

Gallant, S. N.; Kennedy, B. L.; Bachman, S. L.; Huang, R.; Lee, T.-H.; Mather, M.

10.1101/2021.07.02.450802 — neuroscience — Posted on 2021-07-03

3744 A topographical and physiological exploration of C-tactile afferents and their response to menthol and histamine.

Loken, L. S.; Backlund Wasling, H.; Olausson, H.; McGlone, F. S.; Wessberg, J.

10.1101/2021.07.02.450784 — neuroscience — Posted on 2021-07-03

3745 Increased oscillatory power in a computational model of the olfactory bulb due to synaptic degeneration

Berry, K.; Cox, D.

10.1101/2020.08.06.239293 — neuroscience — Posted on 2021-07-03

3746 Conjunctive spatial and idiothetic codes are topographically organized in the GABAergic cells of the lateral septum

van der Veldt, S.; Etter, G.; Mosser, C.-A.; Manseau, F.; Williams, S.

10.1101/2020.11.03.366849 — neuroscience — Posted on 2021-07-03

3747 Early functional and cognitive declines measured by auditory evoked cortical potentials in Alzheimer's disease mice

Mei, L.; Liu, L.-M.; Chen, K.; Zhao, H.-B.

10.1101/2021.02.25.432945 — neuroscience — Posted on 2021-07-03

3748 The spatial transcriptomic landscape of the healing intestine following damage

Parigi, S. M.; Larsson, L.; Das, S.; Ramirez Flores, R. O.; Frede, A.; Tripathi, K.; Diaz, O.; Selin, K.; Morales, R. A.; Luo, X.; Monasterio, G.; Engblom, C.; Gagliani, N.; Saez, J.; Lundeberg, J.; Villablanca, E. J.

10.1101/2021.07.01.450768 — systems biology — Posted on 2021-07-03

3749 Associations between Acoustic Features of Maternal Speech and Infants' Emotion Regulation following a Social Stressor

Kolacz, J.; daSilva, E. B.; Lewis, G. F.; Bertenthal, B. I.; Porges, S. W.

10.1101/2021.07.02.450379 — physiology — Posted on 2021-07-03

3750 Gradient-mixing LEGO robots for purifying DNA origami nanostructures of multiple components rate-zonal centrifugation

Sentosa, J.; Horne, B.; Djutanta, F.; Showkeir, D.; Rezvani, R.; Hariadi, R. F.

10.1101/2021.07.02.450731 — biophysics — Posted on 2021-07-03

3751 Knowledge-based antibody repertoire simulation, a novel allele detection tool evaluation and application

Yang, X.; Zhu, Y.; Zeng, H.; Chen, S.; Guan, J.; Wang, Q.-L.; Lan, C.; Sun, D.; Yu, X.; Zhang, Z.

10.1101/2021.07.01.450681 — bioinformatics — Posted on 2021-07-02

3752 Locality-sensitive hashing enables signal classification in high-throughput mass spectrometry raw data at scale

Bob, K.; Teschner, D.; Kemmer, T.; Gomez-Zepeda, D.; Tenzer, S.; Schmidt, B.; Hildebrandt, A.

10.1101/2021.07.01.450702 — bioinformatics — Posted on 2021-07-02

3753 In-silico pharmacophore and Molecular Docking based drug discovery against Marburg Virus Viral Protein VP35; A potent of MAVD.

Quazi, S.; Gavas, S.; Malik, J. A.; Suman, K. S.; Haider, Z.

10.1101/2021.07.01.450693 — bioinformatics — Posted on 2021-07-03

3754 Characterizing collaborative transcription regulation with a graph-based deep learning approach

Zhang, Z.; Feng, F.; Yao, Y.; Liu, J.

10.1101/2021.07.01.450813 — bioinformatics — Posted on 2021-07-03

3755 A comparative life cycle analysis of electromicrobial production systems

Abel, A. J.; Adams, J. D.; Clark, D. S.

10.1101/2021.07.01.450744 — bioengineering — Posted on 2021-07-02

3756 OpenSense: An open-source toolbox for Inertial-Measurement-Unit-based measurement of lower extremity kinematics over long durations

Al Borno, M.; O'Day, J.; Ibarra, V.; Dunne, J.; Seth, A.; Habib, A.; Ong, C.; Hicks, J.; Uhlrich, S.; Delp, S.

10.1101/2021.07.01.450788 — bioengineering — Posted on 2021-07-02

3757 On the contingent nature of satellite DNA evolution

Camacho, J. P. M.; Cabrero, J.; Lopez-Leon, M. D.; Martin-Pecina, M.; Perfectti, F.; Garrido-Ramos, M. A.; Ruiz-Ruano, F. J.

10.1101/2021.07.01.450629 — genomics — Posted on 2021-07-03

3758 Interplay between BALL and CBP maintains H3K27 acetylation on active genes in Drosophila

Khan, M. H. F.; Shaukat, A.; Umer, Z.; Ahmad, H.; Tariq, M.

10.1101/2021.07.02.450821 — genomics — Posted on 2021-07-03

3759 Broad-scale variation in human genetic diversity levels is predicted by purifying selection on coding and non-coding elements

Murphy, D.; Elyashiv, E.; Amster, G.; Sella, G.

10.1101/2021.07.02.450762 — evolutionary biology — Posted on 2021-07-02

3760 More-curated data outperforms more data: treatment of cryptic and known paralogs improves phylogenomic analysis and resolves a northern Andean origin of Freziera (Pentaphylacaceae)

Frost, L. A.; Lagomarsino, L. P.

10.1101/2021.07.01.450750 — evolutionary biology — Posted on 2021-07-02

3761 Using stationary vital rates in impact assessments may underestimate potential threat

Horswill, C.; Miller, J.; Wood, M. J.

10.1101/2021.07.01.450685 — ecology — Posted on 2021-07-02

3762 Combining taxonomic, phylogenetic and functional diversity reveals new global priority areas for tetrapod conservation

Tordoni, E.; Toussaint, A.; Pärtel, M.; Nogues-Bravo, D.; Carmona, C. P.

10.1101/2021.07.01.450689 — ecology — Posted on 2021-07-02

3763 Aboveground biomass increments over 26 years (1993-2019) in an old-growth cool-temperate forest in northern Japan

Noguchi, M.; Hoshizaki, K.; Matsushita, M.; Sugiura, D.; Yagihashi, T.; Saitoh, T.; Itabashi, T.; Kazuhide, O.; Shibata, M.; Hoshino, D.; Masaki, T.; Osumi, K.; Takahashi, K.; Suzuki, W.

10.1101/2021.07.02.450668 — ecology — Posted on 2021-07-02

3764 Effects of warming winter embryo incubation temperatures on larval cisco (Coregonus artedi) survival, growth, and critical thermal maximum

Stewart, T. R.; Vinson, M. R.; Stockwell, J. D.

10.1101/2021.07.01.450800 — ecology — Posted on 2021-07-03

3765 Amino acid and nucleotide metabolism shape the selection of trophic levels in animals

Yu, R.; Wang, H.; Nielsen, J.

10.1101/2021.07.01.450789 — ecology — Posted on 2021-07-03

3766 Neutrophil and natural killer cell imbalances prevent muscle stem cell mediated regeneration following murine volumetric muscle loss

Larouche, J. A.; Kurpiers, S. J.; Yang, B. A.; Davis, C.; Fraczek, P. M.; Hall, M.; Brooks, S. V.; Shea, L. D.; Aguilar, C. A.

10.1101/2021.07.02.450777 — cell biology — Posted on 2021-07-02

3767 Clonal dynamics of normal hepatocyte expansions in homeostatic human livers and their association with the biliary epithelium

Passman, A.; Haughey, M. J.; Carlotti, E.; Williams, M. J.; Cereser, B. J.; Lin, M.-L.; Devkumar, S.; Gabriel, J. p.; Russo, F. P.; Hoare, M.; Jansen, M.; Chin-Aleong, J.; Wright, N. A.; Kocher, H.; Huang, W.; Alison, M. R.; McDonald, S. A.

10.1101/2021.07.02.450704 — cell biology — Posted on 2021-07-02

3768 Mapping Protein Numbers in Living Cells

Thirstrup, D. J.; Yao, J.; Sherman, J.; Mueller, I. A.; Wiegraebe, W.

10.1101/2021.07.02.450806 — cell biology — Posted on 2021-07-03

3769 Differential impact of TNFRSF co-stimulation on CD8+ T cell cytokine production by feedback control of surface receptor expression

Nguyen, J.; Pettmann, J.; Kruger, P.; Dushek, O.

10.1101/2021.07.02.450833 — immunology — Posted on 2021-07-03

3770 Edge-centric analysis of time-varying functional brain networks with applications in autism spectrum disorder

Zamani Esfahlani, F.; Byrge, L.; Tanner, J.; Sporns, O.; Kennedy, D.; Betzel, R.

10.1101/2021.07.01.450812 — neuroscience — Posted on 2021-07-02

3771 Identifying components that vary in space and time from resting-state functional MRI

Scott, G.; Leech, R.

10.1101/2021.07.01.450675 — neuroscience — Posted on 2021-07-02

3772 Wild lab: A naturalistic free viewing experiment reveals previously unknown EEG signatures of face processing.

Gert, A. L.; Ehinger, B. V.; Timm, S.; Kietzmann, T. C.; Koenig, P.

10.1101/2021.07.02.450779 — neuroscience — Posted on 2021-07-02

3773 Network diffusion model predicts neurodegeneration in limb-onset amyotrophic lateral sclerosis

Bhattarai, A.; Chen, Z.; Chua, P.; Talman, P.; Mathers, S.; Chapman, C.; Howe, J.; Lee, C. S.; Lie, Y.; Poudel, G. R.; Egan, G. F.

10.1101/2021.07.02.450445 — neuroscience — Posted on 2021-07-02

3774 Postsynaptic plasticity of cholinergic synapses underlies the induction and expression of appetitive memories in Drosophila

Pribbenow, C.; Chen, Y.-c.; Heim, M.-M.; Laber, D.; Reubold, S.; Reynolds, E.; Balles, I.; Suarez Grimalt, R.; Rauch, C.; Roesner, J.; Fernandez-d.V. Alquicira, T.; Owald, D.

10.1101/2021.07.01.450776 — neuroscience — Posted on 2021-07-02

3775 Hippocampal theta oscillations are modulated by behaviour in the ferret but persist during both locomotion and immobility

Dunn, S. L. S.; Town, S. M.; Bizley, J. K.; Bendor, D.

10.1101/2021.07.01.450507 — neuroscience — Posted on 2021-07-03

3776 A validation standard for Area of Habitat maps for terrestrial birds and mammals

Dahal, P. R.; Lumbierres, M.; Butchart, S. H. M.; Donald, P. F.; Rondinini, C.

10.1101/2021.07.02.450824 — zoology — Posted on 2021-07-02

3777 Signaling receptor localization maximizes cellular information acquisition in spatially-structured, natural environments

Wang, Z. J.; Thomson, M.

10.1101/2021.07.01.450787 — systems biology — Posted on 2021-07-02

3778 PEPSDI: Scalable and flexible inference framework for stochastic dynamic single-cell models

Persson, S.; Welkenhuysen, N.; Shashkova, S.; Wiqvist, S.; Reith, P.; Schmidt, G. W.; Picchini, U.; Cvijovic, M.

10.1101/2021.07.01.450748 — systems biology — Posted on 2021-07-02

3779 Identifying Site-specific Superoxide and Hydrogen Peroxide Production Rates from the Mitochondrial Electron Transport System Using a Computational Strategy

Duong, Q. V.; Levitsky, Y.; Dessinger, M. J.; Bazil, J. N.

10.1101/2021.07.01.450791 — systems biology — Posted on 2021-07-02

3780 Understanding hydropower impacts on Amazonian wildlife is limited by a lack of robust evidence: results from a systematic review

Rodrigues dos Santos, E.; Michalski, F.; Norris, D.

10.1101/2021.07.01.450737 — scientific communication and education — Posted on 2021-07-02

3781 The impact of heat on human physical work capacity; Part III: the impact of solar radiation varies with air temperature, humidity, and clothing coverage.

Foster, J.; Smallcombe, J. W.; Hodder, S. G.; Flouris, A. D.; Nybo, L.; Havenith, G.

10.1101/2021.07.01.449782 — physiology — Posted on 2021-07-02

3782 Time to recover from daily caffeine intake.

Lin, Y.-S.; Weibel, J.; Landolt, H.-P.; Santini, F.; Garbazza, C.; Kistler, J.; Rehm, S. S.; Rentsch, K.; Borgwardt, S.; Cajochen, C.; Reichert, C.

10.1101/2021.07.01.450708 — pharmacology and toxicology — Posted on 2021-07-02

3783 The Effect of a Fennel Extract on the STAT Signaling and Intestinal Barrier Function

Rabalais, J.; Kozan, P.; Lu, T.; Durali, N.; Okamoto, K.; Das, B.; McGeough, M. D.; Lee, J. B.; Barrett, K. E.; Marchelletta, R.; Sivagnanam, M.

10.1101/2021.07.01.450766 — pharmacology and toxicology — Posted on 2021-07-02

3784 Sulfated polysaccharides from red seaweed Gracilaria cornea induce macrophages polarization to an antitumor M1 phenotype

Teles, F. B.; Assef, A. N. B.; Andrade, R. M.; Soares, V. V. M.; Alves, A. W. d. S.; Lima-Junior, R. C. P.; Benevides, N. M. B.; Wilke, D. V.

10.1101/2021.07.01.450714 — pharmacology and toxicology — Posted on 2021-07-02

3785 The role of pro- and antiangiogenic factors in angiogenesis process by Raman spectroscopy

Monika, K.; Halina, A.

10.1101/2021.07.02.450827 — cancer biology — Posted on 2021-07-02

3786 SPOROS: A pipeline to analyze DISE/6mer seed toxicity

Bartom, E.; Kocherginsky, M.; Paudel, B.; Vaidyanathan, A.; Haluck-Kangas, A.; Patel, M.; O'Shea, K.; Murmann, A.; Peter, M. E.

10.1101/2021.07.01.450720 — bioinformatics — Posted on 2021-07-02

3787 FishExp: a comprehensive database and analysis platform for gene expression and alternative splicing of fish species

Tan, S.; Wang, W.; Jie, W.; Liu, J.

10.1101/2021.07.01.450804 — bioinformatics — Posted on 2021-07-02

3788 Mining all publicly available expression data to compute dynamic microbial transcriptional regulatory networks

Sastry, A. V.; Poudel, S.; Rychel, K.; Yoo, R.; Lamoureux, C. R.; Chauhan, S.; Haiman, Z. B.; Al Bulushi, T.; Seif, Y.; Palsson, B. O.

10.1101/2021.07.01.450581 — bioinformatics — Posted on 2021-07-02

3789 ionbot: a novel, innovative and sensitive machine learning approach to LC-MS/MS peptide identification

Degroeve, S.; Gabriels, R.; Velghe, K.; Bouwmeester, R.; Tichshenko, N.; Martens, L.

10.1101/2021.07.02.450686 — bioinformatics — Posted on 2021-07-02

3790 Temporal Gene Expression in Apical Culms Shows Early Changes in Cell Wall Biosynthesis Genes in Sugarcane

Hosaka, G. K.; Correr, F. H.; Silva, C. C.; Sforca, D. A.; Zatti Barreto, F.; Almeira Balsalobre, T. W.; Pasha, A.; de Souza, A. P.; Provart, N. J.; Carneiro, M. S.; Margarido, G. R. A.

10.1101/2021.07.01.450585 — genomics — Posted on 2021-07-02

3791 An Automated SNP-Based Approach for Contaminant Identification in Biparental Polyploid Populations of Tropical Forage Grasses

Martins, F. B.; Moraes, A. d. C. L.; Aono, A. H.; Ferreira, R. C. U.; Chiari, L.; Simeao, R. M.; Barrios, S. C. L.; Santos, M. F.; Jank, L.; do Valle, C. B.; Vigna, B.; de Souza, A. P.

10.1101/2021.07.01.450796 — genomics — Posted on 2021-07-02

3792 Inducible Yeast Two-Hybrid with Quantitative Measures

Hernandez, J.; Ross, K. D.; Hamilton, B. A.

10.1101/2021.07.01.450807 — genetics — Posted on 2021-07-02

3793 Evolution and diversity of bat and rodent Paramyxoviruses from North America

Larsen, B. B.; Gryseels, S.; Otto, H. W.; Worobey, M.

10.1101/2021.07.01.450817 — evolutionary biology — Posted on 2021-07-02

3794 DETECTING PHYLODIVERSITY-DEPENDENT DIVERSIFICATION WITH A GENERAL PHYLOGENETIC INFERENCE FRAMEWORK

Richter, F.; Wit, E. C.; Etienne, R. S.; Janzen, T.; Hildenbrandt, H.

10.1101/2021.07.01.450729 — evolutionary biology — Posted on 2021-07-02

3795 Functional constraints on insect immune system components govern their evolutionary trajectories

Ruzzante, L.; Feron, R.; Reijnders, M. J.; Thiebaut, A.; Waterhouse, R. M.

10.1101/2021.07.02.450559 — evolutionary biology — Posted on 2021-07-02

3796 Diversity begets diversity through shared adaptive genetic variation: discovery of a cryptic wide-mouthed scale-eater

Richards, E.; Martin, C. H.

10.1101/2021.07.01.450755 — evolutionary biology — Posted on 2021-07-02

3797 Knockout of Anopheles stephensi immune gene LRIM1 by CRISPR-Cas9 reveals its unexpected role in reproduction and vector competence

Inbar, E.; Eappen, A.; Alford, R. T.; Reid, W.; Harrell, R. A.; Hosseini, M.; Chakravarty, S.; Li, T.; Sim, B. K. L.; Billingsley, P. F.; Hoffman, S. L.

10.1101/2021.07.02.450840 — microbiology — Posted on 2021-07-02

3798 Behavioral origin of sound-evoked activity in visual cortex

Bimbard, C.; Sit, T. P.; Lebedeva, A.; Harris, K. D.; Carandini, M.

10.1101/2021.07.01.450721 — neuroscience — Posted on 2021-07-02

3799 Maturation of distinct neural components of the cognitive control network support early development of inhibitory control

Berger, P.; Grosse Wiesmann, C.; Friederici, A. D.

10.1101/2021.07.02.450852 — neuroscience — Posted on 2021-07-02

3800 Atypical gaze patterns in autism are heterogeneous across subjects but reliable within individuals

Keles, U.; Kliemann, D.; Byrge, L.; Saarimaki, H.; Paul, L. K.; Kennedy, D. P.; Adolphs, R.

10.1101/2021.07.01.450793 — neuroscience — Posted on 2021-07-02

3801 Living with high potassium: an asset or a hindrance

Pantha, P.; Oh, D.-H.; Longstreth, D. J.; Dassanayake, M.

10.1101/2021.07.01.450778 — plant biology — Posted on 2021-07-02

3802 Large-scale topological disruption of chromosome territories 9 and 22 is associated with nonresponse to treatment in CML

Fabian-Morales, E.; Vallejo Escamilla, D. G.; Gomez, A. A. G.; Rodriguez, A.; Gonzalez-Barrios, R.; Rodriguez-Torres, Y. L.; Henandez, C. C.; de la Torre Lujan, A.; Rico, D. A. O.; Guzman, E. C. O.; Saavedra, A. L.; Frias, S.; Montalvo, L. A. H.

10.1101/2021.07.01.450740 — cancer biology — Posted on 2021-07-02

3803 High confidence identification of intra-host single nucleotide variants for person-to-person influenza transmission tracking in congregate settings

Maljkovic Berry, I.; Treangen, T.; Fung, C.; Tai, S.; Pollett, S.; Hong, F.; Li, T.; Pireku, P.; Thomanna, A.; German, J.; Bueno de Mesquita, P. J.; Rutvisuttinunt, W.; Panciera, M.; Lidl, G.; Frieman, M.; Jarman, R. G.; Milton, D. K.

10.1101/2021.07.01.450528 — genomics — Posted on 2021-07-02

3804 Single cell characterization of CRISPR-modified transcript isoforms with nanopore sequencing

Kim, H. S.; Grimes, S. M.; Hooker, A. C.; Lau, B. T.; Ji, H. P.

10.1101/2021.07.01.450805 — genomics — Posted on 2021-07-02

3805 Xrp1 and Irbp18 trigger a feed-forward loop of proteotoxic stress to induce the loser status

Langton, P. F.; Baumgartner, M. E.; Logeay, R.; Piddini, E.

10.1101/2021.07.02.450835 — genetics — Posted on 2021-07-02

3806 Accurate profiling of forensic autosomal STRs using the Oxford Nanopore Technologies MinION device

Hall, C. L.; Kesharwani, R. K.; Phillips, N. R.; Planz, J. V.; Sedlazeck, F. J.; Zascavage, R. R.

10.1101/2021.07.01.450747 — genetics — Posted on 2021-07-02

3807 Aspects of the Neurospora crassa sulfur starvation response are revealed by transcriptional profiling and DNA affinity purification sequencing

Huberman, L. B.; Wu, V. W.; Lee, J.; Daum, C.; O'Malley, R.; Glass, N. L.

10.1101/2021.07.01.450814 — genetics — Posted on 2021-07-02

3808 Reduction of Derlin activity suppresses Notch-dependent tumours in the C. elegans germ line

Singh, R.; Smit, R.; Wang, X.; Wang, C.; Racher, H.; Hansen, D.

10.1101/2021.07.02.450841 — genetics — Posted on 2021-07-02

3809 Evidence that nuclear receptors evolved from terpene synthases

Houston, D. R.; Hanna, J. G.; Lathe, J. C.; Hillier, S. G.; Lathe, R.

10.1101/2021.06.29.450438 — evolutionary biology — Posted on 2021-07-02

3810 Optimized nickase- and nuclease-based prime editing in human and mouse cells

Adikusuma, F.; Lushington, C.; Arudkumar, J.; Godahewa, G. I.; Chey, Y. C. J.; Gierus, L.; Piltz, S.; Reti, D.; Wilson, L.; Bauer, D.; Thomas, P.

10.1101/2021.07.01.450810 — molecular biology — Posted on 2021-07-02

3811 Eukaryotic stress induced mutagenesis is limited by a local control of Translesion Synthesis

Maslowska, K.; Villafanez, F.; Laureti, L.; Iwai, S.; Pages, V.

10.1101/2021.07.02.450853 — molecular biology — Posted on 2021-07-02

3812 Diversity and distribution of sulfur metabolism in the human gut microbiome and its association with colorectal cancer

Wolf, P. G.; Cowley, E. S.; Breister, A.; Matatov, S.; Lucio, L.; Polak, P.; Ridlon, J. M.; Gaskins, H. R.; Anantharaman, K.

10.1101/2021.07.01.450790 — microbiology — Posted on 2021-07-02

3813 Evolution of the quorum sensing regulon in cooperating populations of Pseudomonas aeruginosa

Smalley, N. E.; Schaefer, A. L.; Asfahl, K. L.; Perez, C.; Greenberg, E. P.; Dandekar, A. A.

10.1101/2021.07.01.450773 — microbiology — Posted on 2021-07-02

3814 Small and equipped: the rich repertoire of antibiotic resistance genes in Candidate Phyla Radiation genomes

Maatouk, M.; Ibrahim, A.; Rolain, J.-M.; Merhej, V.; Bittar, F.

10.1101/2021.07.02.450847 — microbiology — Posted on 2021-07-02

3815 Phenogenomic characterization of a newly domesticated and novel species from the genus Verrucosispora

Kennedy, S.; Atkinson, C.; Tomlinson, B.; Hammond, L.; Eswara, P. J.; Baker, B. J.; Shaw, L. N.

10.1101/2021.07.01.450820 — microbiology — Posted on 2021-07-02

3816 Knockdown of astrocytic monocarboxylate transporter 4 (MCT4) in the motor cortex leads to loss of dendritic spines and a deficit in motor learning

Lundquist, A. J.; Llewellyn, G. N.; Kishi, S. H.; Jakowec, N. A.; Cannon, P. M.; Petzinger, G. M.; Jakowec, M. W.

10.1101/2021.07.01.450797 — neuroscience — Posted on 2021-07-02

3817 Machine learning of all Mycobacterium Tuberculosis H37Rv RNA-seq data reveals complex interplay between metabolism, stress response, and infection

Yoo, R.; Rychel, K.; Poudel, S.; Al-bulushi, T.; Yuan, Y.; Chauhan, S.; Lamoureux, C.; Palsson, B.; Sastry, A. V.

10.1101/2021.07.01.450045 — systems biology — Posted on 2021-07-02

3818 Gaussian accelerated molecular dynamics reveals that a proline-rich signaling peptide frequently samples cis conformations when unbound

Alcantara, J.; Stix, R.; Huang, K.; Connor, A.; East, R.; Jaramillo-Martinez, V.; Stollar, E. J.; Ball, K. A.

10.1101/2021.07.01.450746 — biophysics — Posted on 2021-07-02

3819 Between two walls: Modeling the adsorption behavior of β-glucosidase A on bare and SAM-functionalised gold surfaces

Bourassin, N.; Barbault, F.; Baaden, M.; Sacquin-Mora, S.

10.1101/2021.07.02.450859 — biophysics — Posted on 2021-07-02

3820 Suppression of sost/sclerostin and dikkopf-1 promote intervertebral disc structure in mice

Kroon, T. M.; Niziolek, P.; Edwards, D.; Clinkenbeard, E. L.; Robling, A. G.; Holguin, N.

10.1101/2021.07.01.449486 — bioengineering — Posted on 2021-07-02

3821 RGEN-SEQ FOR HIGHLY SENSITIVE AMPLIFICATION-FREE SCREEN OF OFF-TARGET SITES OF GENE EDITORS

Kuzin, A.; Redler, B.; Onuska, J.; Slesarev, A.

10.1101/2021.07.01.450795 — genomics — Posted on 2021-07-02

3822 Fungal community composition along a gradient of permafrost thaw

Kluge, M.; Wurzbacher, C.; Wauthy, M.; Engelbrecht Clemmensen, K.; Hawkes, J.; Einarsdottir, K.; Stenlid, J.; Peura, S.

10.1101/2021.07.01.450738 — ecology — Posted on 2021-07-02

3823 Natural infection of SARS-CoV-2 delta variant in Asiatic lions (Panthera leo persica) in India

Mishra, A.; Kumar, N.; Bhatia, S.; Aasdev, A.; Kanniappan, S.; Thayasekhar, A.; Gopinadhan, A.; Silambarasan, R.; Sreekumar, C.; Dubey, C. K.; Tripathi, M.; Raut, A. A.; Singh, V. P.

10.1101/2021.07.02.450663 — microbiology — Posted on 2021-07-02

3824 Neutralization of Delta variant with sera of Covishield vaccinees and COVID-19 recovered vaccinated individuals

Sapkal, G.; Yadav, P. D.; Sahay, R. R.; Deshpande, G.; Gupta, N.; Nyayanit, D. A.; Patil, D. Y.; Kumar, S.; Abraham, P.; Panda, S.; Bhargava, B.

10.1101/2021.07.01.450676 — microbiology — Posted on 2021-07-02

3825 Idiopathic chronic diarrhea in rhesus macaques is not associated with enteric viral infections

Delwart, E.; Tisza, M. J.; Altan, E.; Li, Y.; Deng, X.; Hartigan-O'Connor, J. D.; Ardeshir, A.

10.1101/2021.07.01.450785 — microbiology — Posted on 2021-07-02

3826 Extracellular ribosomal RNA provides a window into taxon-specific microbial lysis

Zhong, K. X.; Chan, A. M.; Wirth, J. F.; Suttle, C. A.

10.1101/2021.07.02.450638 — microbiology — Posted on 2021-07-02

3827 Loss of GdpP function in Staphylococcus aureus leads to β-lactam tolerance and enhanced evolution of β-lactam resistance

Poon, R.; Basuino, L.; Satishkumar, N.; Chatterjee, A.; Mukkayyan, N.; Buggeln, E.; Huang, L.; Nair, V.; Argudin, M. A.; Datta, S. K.; Chambers, H. F.; Chatterjee, S. S.

10.1101/2021.07.02.449101 — microbiology — Posted on 2021-07-02

3828 Regulatory small RNA, Qrr2, is expressed independently of sigma factor-54 and functions autonomously in Vibrio parahaemolyticus to control quorum sensing

Tague, J.; Hong, J.; Kalburge, S. S.; Boyd, E. F.

10.1101/2021.07.01.450815 — microbiology — Posted on 2021-07-02

3829 Uncontrolled CD21low age-associated and B1 B cell accumulation caused by failure of an EGR2/3 tolerance checkpoint

Masle-Farquhar, E.; Peters, T. J.; Miosge, L. A.; Parish, I. A.; Weigel, C.; Oakes, C. C.; Reed, J. H.; Goodnow, C.

10.1101/2021.07.01.450650 — immunology — Posted on 2021-07-02

3830 Qualification of ELISA and neutralization methodologies to measure SARS-CoV-2 humoral immunity using human clinical samples

Larsen, S. E.; Berube, B. J.; Pecor, T.; Cross, E.; Brown, B. P.; Williams, B.; Johnson, E.; Qu, P.; Carter, L.; Wren, S.; Kepl, E.; Sydeman, C.; King, N. P.; Baldwin, S. L.; Coler, R. N.

10.1101/2021.07.02.450915 — immunology — Posted on 2021-07-02

3831 Flavonols and dihydroflavonols inhibit the main protease activity of SARS-CoV-2 and the replication of human coronavirus 229E

Zhu, Y.; Scholle, F.; Kisthardt, S. C.; Xie, D.

10.1101/2021.07.01.450756 — biochemistry — Posted on 2021-07-02

3832 Implications of Spike-glycoprotein processing at S1/S2 by Furin, at S2' by Furin and/or TMPRSS2 and shedding of ACE2: cell-to-cell fusion, cell entry and infectivity of SARS-CoV-2

10.1101/2021.07.02.450896 — biochemistry — Posted on 2021-07-02

3833 Chasing perfection: validation and polishing strategies for telomere-to-telomere genome assemblies

Mc Cartney, A. M.; Shafin, K.; Alonge, M.; Bzikadze, A. V.; Formenti, G.; Fungtammasan, A.; Howe, K.; Jain, C.; Koren, S.; Logsdon, G. A.; Miga, K. H.; Mikheenko, A.; Paten, B.; Shumate, A.; Soto, D. C.; Sovic, I.; Wood, J. M.; Zook, J. M.; Phillippy, A. M.; Rhie, A.

10.1101/2021.07.02.450803 — genomics — Posted on 2021-07-02

3834 Betacoronavirus-specific alternate splicing

Karlebach, G.; Aronow, B. J.; Baylin, S. J.; Butler, D.; Foox, J.; Levy, S.; Meydan, C.; Mozsary, C.; Saravia-Butler, A. M.; Taylor, D. M.; Wurtele, E.; Mason, C.; Beheshti, A.; Robinson, P. N.

10.1101/2021.07.02.450920 — genomics — Posted on 2021-07-02

3835 DUSP6 mediates resistance to JAK2 inhibition and drives leukemic progression

Kong, T.; Laranjeira, A. B. A.; Yang, K.; Fisher, D.; Yu, L.; Wang, A. Z.; Ruzinova, M.; Fowles, J.; Allen, M.; Celik, H.; Challen, G.; Huang, S.; Oh, S.

10.1101/2021.06.27.449656 — cancer biology — Posted on 2021-07-02

3836 Highly efficient synthetic CRISPR RNA/Cas9-based mutagenesis for cardiovascular phenotypic screening in F0 zebrafish

Quick, R. E.; Parab, S.; Tolbert, Z. R.; Matsuoka, R. L.

10.1101/2021.07.01.450753 — developmental biology — Posted on 2021-07-02

3837 In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor.

Baker, F. C.; Neiswender, H.; Veeranan-Karmegam, R.; Gonsalvez, G. B.

10.1101/2021.07.01.450794 — cell biology — Posted on 2021-07-02

3838 Acquisition of cancer stem cell properties during EMT requires cell division

den Hollander, P.; Vasaikar, S. V.; Castaneda, M.; Joseph, R.; Deshmukh, A. P.; Zhao, T.; Pietila, M.; Fu, C.; Symmans, W. F.; Soundararajan, R.; Mani, S. A.

10.1101/2021.07.01.449976 — cell biology — Posted on 2021-07-02

3839 Immune complex solubility and size govern Fc-gamma receptor responses: A scalable cell-based reporter system

Chen, H.; Maul-Pavicic, A.; Holzer, M.; Salzer, U.; Chevalier, N.; Voll, R. E.; Hengel, H.; Kolb, P.

10.1101/2020.11.11.378232 — immunology — Posted on 2021-07-02

3840 Individualized event structure drives individual differences in whole-brain functional connectivity

Betzel, R.; Cutts, S.; Greenwell, S.; Sporns, O.

10.1101/2021.03.12.435168 — neuroscience — Posted on 2021-07-02

3841 Distinct roles of nonmuscle myosin II isoforms for establishing tension and elasticity during cell morphogenesis

Weissenbruch, K.; Grewe, J.; Hippler, M.; Fladung, M.; Tremmel, M.; Stricker, K.; Schwarz, U. S.; Bastmeyer, M.

10.1101/2020.10.09.333203 — biophysics — Posted on 2021-07-02

3842 Assembled Cell-Decorated Collagen (AC-DC) bioprinted implants mimic musculoskeletal tissue properties and promote functional recovery

Christensen, K. W.; Turner, J.; Coughenour, K.; Maghdouri-White, Y.; Bulysheva, A. A.; Sergeant, O.; Rariden, M.; Randazzo, A.; Sheean, A. J.; Christ, G. J.; Francis, M. P.

10.1101/2021.06.22.449431 — bioengineering — Posted on 2021-07-02

3843 Investigating age- and sex-specific effects of socialization on voluntary ethanol administration using a novel vapor paradigm

Walker, C. D.; Sexton, H. G.; Risher, M.-L.

10.1101/2020.11.02.364927 — neuroscience — Posted on 2021-07-02

3844 Development of epigenetic clocks for New Zealand livestock

Caulton, A.; Dodds, K. G.; McRae, K. M.; Couldrey, C.; Horvath, S.; Clarke, S. M.

10.1101/2021.06.30.450497 — genomics — Posted on 2021-07-02

3845 Coexistence patterns and diversity in a trait-based metacommunity on an environmental gradient

Mohammed, M.; Blasius, B.; Ryabov, A.

10.1101/2021.06.15.448245 — ecology — Posted on 2021-07-02

3846 In vitro Evaluation of Lytic Phages for Carbapenem-Resistant Klebsiella pneumoniae Isolates

Li, N.; Zeng, Y.; Zhang, Y.; Bao, R.; Hu, B.; Zhu, T.; Tan, D.

10.1101/2021.06.30.450654 — microbiology — Posted on 2021-07-02

3847 Neural attentional-filter mechanisms of listening success in middle-aged and older individuals

Tune, S.; Alavash, M.; Fiedler, L.; Obleser, J.

10.1101/2020.05.20.105874 — neuroscience — Posted on 2021-07-02

3848 Rapid synaptic plasticity contributes to a learned conjunctive code of position and choice-related information in the hippocampus

Zhao, X.; Hsu, C.-L.; Spruston, N.

10.1101/2021.06.30.450574 — neuroscience — Posted on 2021-07-02

3849 Extent, impact, and mitigation of batch effects in tumor biomarker studies using tissue microarrays

Stopsack, K. H.; Tyekucheva, S.; Wang, M.; Gerke, T. A.; Vaselkiv, J. B.; Penney, K. L.; Kantoff, P. W.; Finn, S. P.; Fiorentino, M.; Loda, M.; Lotan, T. L.; Parmigiani, G.; Mucci, L. A.

10.1101/2021.06.29.450369 — pathology — Posted on 2021-07-02

3850 The Myogenesis Program Drives Clonal Selection and Drug Resistance in Rhabdomyosarcoma

Patel, A. G.; Chen, X.; Huang, X.; Clay, M. R.; Komarova, N.; Krasin, M. J.; Pappo, A.; Tillman, H.; Orr, B. A.; McEvoy, J.; Gordon, B.; Blankenship, K.; Reilly, C.; Zhou, X.; Norrie, J. L.; Karlstrom, A.; Yu, J.; Wodarz, D.; Stewart, E.; Dyer, M. A.

10.1101/2021.06.16.448386 — cancer biology — Posted on 2021-07-02

3851 Switching an active site helix in dihydrofolate reductase reveals limits to sub-domain modularity

Zhao, V. Y.; Rodrigues, J. V.; Lozovsky, E. R.; Hartl, D. L.; Shakhnovich, E. I.

10.1101/2021.06.18.448971 — biophysics — Posted on 2021-07-02

3852 Aerobiology in High Latitudes: Evidence of Bacteria Acting as Tracer of Warm Air Mass Advection reaching Northern Antarctic Peninsula

Cataldo, M.; Evangelista, H.; Pereira, J. A. A.; Bertho, A. L.; Pellizari, V.; Kuhn, E.; Sampaio, M.; da Cunha, K. D.; Alencar, A.; Amaral, C.

10.1101/2021.06.27.450079 — biophysics — Posted on 2021-07-02

3853 ECCsplorer: a pipeline to detect extrachromosomal circular DNA (eccDNA) from next-generation sequencing data

Mann, L.; Seibt, K. M.; Weber, B.; Heitkam, T.

10.1101/2021.06.08.447410 — bioinformatics — Posted on 2021-07-02

3854 Unsupervised Spatial Embedded Deep Representation of Spatial Transcriptomics

Fu, H.; Xu, H.; Chong, K.; Li, M.; Ang, K. S.; Lee, H. K.; Lin, J.; Chen, A.; Shao, L.; Liu, L.; Chen, J.

10.1101/2021.06.15.448542 — bioinformatics — Posted on 2021-07-02

3855 Benchmarking supervised signature-scoring methods for single-cell RNA sequencing data in cancer

Nighat, N.; Ye, Z.; Chen, Y.; Wang, X.; Zheng, S.

10.1101/2021.06.29.450404 — bioinformatics — Posted on 2021-07-02

3856 Genetic lineage of the Amami islanders inferred from classical genetic markers

Nishikawa, Y.; Ishida, T.

10.1101/2021.04.18.440379 — genetics — Posted on 2021-07-02

3857 Multiple ancestral and a plethora of recent gene duplications during the evolution of the green sensitive opsin genes (RH2) in teleost fishes

Musilova, Z.; Cortesi, F.

10.1101/2021.05.11.443711 — evolutionary biology — Posted on 2021-07-02

3858 Evolution of a minimal cell

Moger-Reischer, R. Z.; Glass, J. I.; Wise, K.; Bittencourt, D.; Sun, L.; Lynch, M.; Lennon, J. T.

10.1101/2021.06.30.450565 — evolutionary biology — Posted on 2021-07-02

3859 Reproductive biology of wild and domesticated Ensete ventricosum: Further evidence for maintenance of sexual reproductive capacity in a vegetatively propagated perennial crop

Tamrat, S.; Borrell, J. S.; Shiferaw, E.; Wondimu, T.; Kallow, S. S.; Davies, R. M.; Dickie, J. B.; Nuraga, G. W.; White, O.; Woldeyes, F.; Demissew, S.; Wilkin, P.

10.1101/2020.04.30.055582 — ecology — Posted on 2021-07-02

3860 Efficient tagging and purification of endogenous proteins for structural studies by single particle cryo-EM

Zhao, J.; Makhija, S.; Huang, B.; Cheng, Y.

10.1101/2021.06.25.449985 — molecular biology — Posted on 2021-07-02

3861 The nematode worm C. elegans chooses between bacterial foods exactly as if maximizing economic utility

Katzen, A.; Chung, H.-K.; Harbaugh, W.; Iacono, C. D.; Jackson, N.; Yu, S.; Flavell, S. W.; Glimcher, P.; Lockery, S.

10.1101/2021.04.25.441352 — neuroscience — Posted on 2021-07-02

3862 On the topochronic map of the human brain dynamics

Sorrentino, P.; Petkoski, S.; Sparaco, M.; Troisi Lopez, E.; Rucco, R.; Signoriello, E.; Baselice, F.; Bonavita, S.; Pirozzi, M. A.; Quarantelli, M.; Sorrentino, G.; Jirsa, V.

10.1101/2021.07.01.447872 — neuroscience — Posted on 2021-07-02

3863 Hematopoietic differentiation is characterized by a transient peak of entropy at a single cell level.

Dussiau, C.; Boussaroque, A.; Gaillard, M.; Bravetti, C.; Zaroili, L.; Knosp, C.; Friedrich, C.; Asquier, P.; Willems, L.; Quint, L.; Bouscary, D.; Fontenay, M.; Espinasse, T.; Plesa, A.; Sujobert, P.; Gandrillon, O.; Kosmider, O.

10.1101/2021.04.30.442092 — systems biology — Posted on 2021-07-02

3864 A Knowledge-guided Mechanistic Model of Synthetic Lethality in the HCT116 Vorinostat-resistant Colon Cancer Xenograft Model Cell-line

Aiyetan, P.

10.1101/2021.06.22.449530 — systems biology — Posted on 2021-07-02

3865 Natural selection promotes the evolution of recombination 2: during the selective process

Gerrish, P. J.; Cordero, F.; Galeota-Sprung, B.; Colato, A.; Vejalla, V.; Sniegowski, P. D.; Hengartner, N. W.

10.1101/2021.06.07.447324 — evolutionary biology — Posted on 2021-07-02

3866 Modeling in yeast how rDNA introns slow growth and increase desiccation tolerance in lichens

Armaleo, D.; Chiou, L.

10.1101/2021.05.01.442275 — molecular biology — Posted on 2021-07-02

3867 Cerebrospinal fluids from healthy pregnant women does not harbor a detectable microbial community

Kang, Y.; Ji, X.; Guo, L.; Xia, H.; Yang, X.; Xie, Z.; Shi, X.; Wu, R.; Feng, D.; Wang, C.; Chen, M.; Zhang, W.; Wei, H.; Guan, Y.; Ye, K.; Zhao, G.

10.1101/2020.09.16.299065 — microbiology — Posted on 2021-07-02

3868 Identification of a family of Vibrio type III secretion system effectors that contain a conserved serine/threonine kinase domain

Plaza, N.; Urrutia, I. M.; Garcia, K.; Waldor, M. K.; Blondel, C. J.

10.1101/2020.12.11.418251 — microbiology — Posted on 2021-07-02

3869 On the topochronic map of the human brain dynamics

Sorrentino, P.; Petkoski, S.; Sparaco, M.; Troisi Lopez, E.; Rucco, R.; Signoriello, E.; Baselice, F.; Bonavita, S.; Pirozzi, M. A.; Quarantelli, M.; Sorrentino, G.; Jirsa, V.

10.1101/2021.07.01.447872 — neuroscience — Posted on 2021-07-02

3870 Oligodendrocytes depend on MCL-1 to prevent spontaneous apoptosis and white matter degeneration

Cleveland, A. H.; Romero-Morales, A.; Alfonso Azcona, L.; Herrero, M.; Nikolova, V. D.; Moy, S.; Elroy-Stein, O.; Gama, V.; Gershon, T. R.

10.1101/2020.12.02.408138 — neuroscience — Posted on 2021-07-02

3871 Disinhibitory circuitry gates associative synaptic plasticity in olfactory cortex

Canto-Bustos, M.; Friason, F. K. E.; Bassi, C.; Oswald, A.-M. M.

10.1101/2020.09.24.312686 — neuroscience — Posted on 2021-07-02

3872 Moving outside the lab: The viability of conducting sensorimotor learning studies online

Tsay, J. S.; Lee, A. S.; Ivry, R. B.; Avraham, G.

10.1101/2021.01.30.181370 — neuroscience — Posted on 2021-07-02

3873 Gated recurrence enables simple and accurate sequence prediction in stochastic, changing, and structured environments

Foucault, C.; Meyniel, F.

10.1101/2021.05.03.442240 — neuroscience — Posted on 2021-07-02

3874 Gymnasts' ability to modulate bioelectric sensorimotor rhythms during kinesthetic motor imagery of sports non-specific movements

Sugino, H.; Ushiyama, J.

10.1101/2021.05.17.444451 — neuroscience — Posted on 2021-07-02

3875 Improved correspondence of fMRI visual field localizer data after macroanatomical alignment

Qubad, M.; Barnes-Scheufler, C. V.; Schaum, M.; Raspor, E.; Roesler, L.; Peters, B.; Goebel, R.; Reif, A.; Bittner, R. A.

10.1101/2021.02.26.433066 — neuroscience — Posted on 2021-07-02

3876 Transcription factor binding activity is the primary driver of noise in gene expression

Parab, L.; Pal, S.; Dhar, R.

10.1101/2020.07.27.222596 — systems biology — Posted on 2021-07-02

3877 Identifying and testing marker-trait associations for growth and phenology in three pine species

Perry, A.; Wachowiak, W.; Beaton, J.; Iason, G.; Cottrell, J.; Cavers, S.

10.1101/2020.12.22.423987 — plant biology — Posted on 2021-07-02

3878 GranatumX: A community engaging, modularized and flexible webtool for single-cell analysis

Zhu, X.; Yunits, B.; Wolfgruber, T.; Liu, Y.; Huang, Q.; Poirion, O.; Arisdakessian, C.; Zhao, T.; Garmire, D.; Garmire, L.; Stanojevic, S.

10.1101/385591 — bioinformatics — Posted on 2021-07-01

3879 CytoSet: Predicting clinical outcomes via set-modeling of cytometry data

Yi, H.; Stanley, N.

10.1101/2021.04.13.439702 — bioinformatics — Posted on 2021-07-02

3880 Natural selection promotes the evolution of recombination 1: among selected genotypes

Gerrish, P. J.; Galeota-Sprung, B. J.; Sniegowski, P. D.; Chevallier, J.; Ycart, B.

10.1101/2021.06.07.447320 — evolutionary biology — Posted on 2021-07-02

3881 Natural selection and the advantage of recombination

Gerrish, P. J.; Galeota-Sprung, B.; Cordero, F.; Sniegowski, P. D.; Colato, A.; Hengartner, N. W.; Vejalla, V.; Chevalier, J.; Ycart, B.

10.1101/2020.08.28.271486 — evolutionary biology — Posted on 2021-07-02

3882 A Guide to Pre-Processing High-Throughput Animal Tracking Data

Gupte, P. R.; Beardsworth, C. E.; Spiegel, O.; Lourie, E.; Toledo, S.; Nathan, R.; Bijleveld, A. I.

10.1101/2020.12.15.422876 — ecology — Posted on 2021-07-02

3883 Impacts of an urban sanitation intervention on fecal indicators and the prevalence of human fecal contamination in Mozambique

Holcomb, D. A.; Knee, J.; Capone, D.; Sumner, T.; Adriano, Z.; Nala, R.; Cumming, O.; Brown, J.; Stewart, J. R.

10.1101/2021.02.19.432000 — microbiology — Posted on 2021-07-02

3884 Cell population migration cycle and response to environmental pH in Bacillus subtilis

Tasaki, S.; Nakayama, M.; Takagi, I.; Wakita, J.-i.; Shoji, W.

10.1101/2020.09.11.292474 — microbiology — Posted on 2021-07-02

3885 Illuminating the plant rhabdovirus landscape through metatranscriptomics data

bejerman, n.; Dietzgen, R.; Debat, H.

10.1101/2021.05.13.443957 — microbiology — Posted on 2021-07-02

3886 Single-cell anatomical analysis of human hippocampus and entorhinal cortex uncovers early-stage molecular pathology in Alzheimer's disease

Davila-Velderrain, J.; Mathys, H.; Mohammadi, S.; Ruzicka, W. B.; Jiang, X.; Ng, A.; Bennett, D. A.; Tsai, L.-H.; Kellis, M.

10.1101/2021.07.01.450715 — neuroscience — Posted on 2021-07-01

3887 Spectro-temporal neural dynamics during sentence completion

Coolen, T.; Dumitrescu, A. M.; Wens, V.; Bourguignon, M.; Gomez, G. L.; Rovai, A.; Sadeghi, N.; Urbain, C.; Goldman, S.; De Tiege, X.

10.1101/2021.07.01.450734 — neuroscience — Posted on 2021-07-01

3888 Hippocampal-medial prefrontal event segmentation and integration contribute to episodic memory formation

Liu, W.; Shi, Y.; Cousins, J. N.; Kohn, N.; Fernandez, G.

10.1101/2020.03.14.990002 — neuroscience — Posted on 2021-07-02

3889 Hierarchical modelling of functional brain networks in population and individuals from big fMRI data

Farahibozorg, S.-R.; Bijsterbosch, J. D.; Gong, W.; Jbabdi, S.; Smith, S. M.; Harrison, S. J.; Woolrich, M. W.

10.1101/2021.02.01.428496 — neuroscience — Posted on 2021-07-02

3890 An empirical evaluation of functional alignment using inter-subject decoding

Bazeille, T.; DuPre, E.; Richard, H.; Poline, J.-B.; Thirion, B.

10.1101/2020.12.07.415000 — neuroscience — Posted on 2021-07-02

3891 CHROMOMETHYLTRANSFERASE3/KRYPTONITE maintain the sulfurea paramutation in Solanum lycopersicum

Martinho, C.; Wang, Z.; Ghigi, A.; Buddle, S.; Barbour, F.; Yarur, A.; Gouil, Q.; Muller, S.; Stam, M.; Liu, C.; Baulcombe, D. C.

10.1101/2021.07.01.450764 — plant biology — Posted on 2021-07-01

3892 Strategies for the site-specific decoration of DNA origami nanostructures with functionally intact proteins

Hellmeier, J.; Platzer, R.; Muehlgrabner, V.; Schneider, M. C.; Kurz, E.; Schuetz, G. J.; Huppa, J. B.; Sevcsik, E.

10.1101/2021.07.01.450695 — biophysics — Posted on 2021-07-01

3893 Biosynthetic Glycan Labeling

Marando, V. M.; Kim, D. E.; Calabretta, P. J.; Kraft, M. B.; Bryson, B. D.; Kiessling, L. L.

10.1101/2021.07.01.450741 — biochemistry — Posted on 2021-07-01

3894 Bayesian inference of clonal expansions in a dated phylogeny

Helekal, D.; Ledda, A.; Volz, E.; Wyllie, D.; Didelot, X.

10.1101/2021.07.01.450370 — evolutionary biology — Posted on 2021-07-01

3895 Programmable Cleavage of Double-stranded DNA by Combined Action of Argonaute CbAgo from Clostridium butyricum and Nuclease Deficient RecBC Helicase from E.coli

Vaiskunaite, R.; Vainauskas, J.; Morris, J.; Potapov, V.; Bitinaite, J.

10.1101/2021.07.01.450725 — molecular biology — Posted on 2021-07-01

3896 Improved Metabolite Prediction Using Microbiome Data-Based Elastic Net Models

Xie, J.; Cho, H.; Lin, B. M.; Pillai, M.; Heimisdottir, L.; Bandyopadhyay, D.; Zou, F.; Roach, J.; Divaris, K.; Wu, D.

10.1101/2021.07.01.450697 — microbiology — Posted on 2021-07-01

3897 Antimicrobial activity of flavonoids glycosides and pyrrolizidine alkaloids from propolis of Scaptotrigona aff. postica.

Campos, T. M. C.; Junior, P. I. d. S.; Negri, G.; do Nascimento, R. M.; Mendonca, R. Z.

10.1101/2021.07.01.450350 — microbiology — Posted on 2021-07-01

3898 Hypervariable-Locus Melting Typing (HLMT): a novel, fast and inexpensive sequencing-free approach to pathogen typing based on High Resolution Melting (HRM) analysis

Perini, M.; Piazza, A.; Panelli, S.; Papaleo, S.; Alvaro, A.; Vailati, F.; Corbella, M.; Saluzzo, F.; Gona, F.; Castelli, D.; Farina, C.; Marone, P.; Cirillo, D. M.; Cavallero, A.; Zuccotti, G. V.; Comandatore, F.

10.1101/2021.07.01.450706 — microbiology — Posted on 2021-07-01

3899 A novel α/β T-cell subpopulation defined by recognition of EPCR

Arrondo, E. E.; Moran-Garrido, M.; Saiz, J.; Barbas, C.; Dichiara Rodriguez, M. G.; Ramirez, N.; Lopez-Sagaseta, J.

10.1101/2021.07.01.450412 — immunology — Posted on 2021-07-01

3900 Dopamine D1 receptor activation and cAMP/PKA signalling mediate Brd4 recruitment to chromatin to regulate gene expression in rat striatal neurons

Jones-Tabah, J.; Martin, R. D.; Chen, J. J.; Tanny, J. C.; Clarke, P. B. S.; Hebert, T.

10.1101/2021.07.01.450754 — neuroscience — Posted on 2021-07-01

3901 Activation of Adipocyte mTORC1 Increases Milk Lipids in a Mouse Model of Lactation

El-Habbal, N.; Meyer, A. C.; Hafner, H.; Redd, J. R.; Carlson, Z.; Mulcahy, M. C.; Gregg, B.; Bridges, D.

10.1101/2021.07.01.450596 — physiology — Posted on 2021-07-01

3902 Effects of High-Volume versus High-Load Resistance Training on Skeletal Muscle Growth and Molecular Adaptations

Vann, C.; Sexton, C.; Osburn, S.; Smith, M.; Haun, C.; Rumbley, M.; Mumford, P.; Ferguson, B.; Montgomery, N.; Fox, C.; Ruple, B.; McKendry, J.; McLeod, J.; Bashir, A.; Beyers, R.; Brook, M.; Smith, K.; Atherton, P.; Beck, D.; McDonald, J.; Young, K.; Phillips, S.; Roberts, M.

10.1101/2021.07.01.450728 — physiology — Posted on 2021-07-01

3903 Acquired resistance to PD-L1 inhibition is associated with an enhanced type I IFN-stimulated secretory program in tumor cells

Shi, Y.; Dolan, M.; Mastri, M.; Hill, J. W.; Dommer, A.; Benzekry, S.; Eng, K.; Ebos, J. M. L.

10.1101/2021.07.01.450417 — cancer biology — Posted on 2021-07-01

3904 Gasdermin B over-expression arbitrates HER2-targeted therapy resistance by inducing protective autophagy

Gamez-Chiachio, M.; Molina-Crespo, A.; Martinez-Val, J.; Martinez, L.; Gassner, K.; Llobet, F. J.; Gonzalo-Consuegra, C.; Cordani, M.; Bernado-Morales, C.; Diaz, E.; Rojo-Sebastian, A.; Trivino, J. C.; Sanchez, L.; Rodriguez-Barrueco, R.; Arribas, J.; Llobet-Navas, D.; Sarrio, D.; Moreno-Bueno, G.

10.1101/2021.07.01.450506 — cancer biology — Posted on 2021-07-01

3905 Drosophila larval models of invasive tumourigenesis for in vivo studies on tumour/peripheral host tissue interactions during cancer cachexia.

Hodgson, J. A.; Parvy, J. P.; Yu, Y.; Cordero, J.

10.1101/2021.07.01.450696 — cancer biology — Posted on 2021-07-01

3906 Nanobodies restore stability to cancer-associated mutants of tumor suppressor protein p16INK4a

Burbidge, O.; Pastok, M. W.; Hodder, S. L.; Zenkeviciute, G.; Noble, M. E.; Endicott, J. A.; Itzhaki, L.

10.1101/2021.07.01.450670 — biochemistry — Posted on 2021-07-01

3907 RNA and the Goldilocks Zone: Where Mg2+ concentration is just right

Guth-Metzler, R.; Mohamed, A. M.; Cowan, E. T.; Frenkel-Pinter, M.; Wartell, R.; Glass, J. B.; Williams, L. D.

10.1101/2021.07.01.450745 — biochemistry — Posted on 2021-07-01

3908 Size Matters: A Mechanistic Model of Nanoparticle Curvature Effects on Amyloid Fibril Formation

John, T.; Adler, J.; Elsner, C.; Petzold, J.; Krueger, M.; Martin, L. L.; Huster, D.; Risselada, H. J.; Abel, B.

10.1101/2021.07.01.450782 — biochemistry — Posted on 2021-07-01

3909 CRISPRa screening with real world evidence identifies potassium channels as neuronal entry factors and druggable targets for SARS-CoV-2

Wang, C.; Dinesh, R.; Qu, Y.; Rustagi, A.; Cousins, H.; Zengel, J.; Guo, Y.; Hall, T.; Beck, A.; Tso, L.; Erdemic, E.; Tanudtanud, K.; Ren, S.; Tzeng, K. T.-H.; Wilk, A.; Wang, M.; Carette, J.; Altman, R.; Blish, C.; Cong, L.

10.1101/2021.07.01.450475 — genomics — Posted on 2021-07-01

3910 Network analysis after epigenome-wide methylation study revealed JUP as a regulator of co-methylated risk-module for T2DM

Bharadwaj, D.; Giri, A.; Prasad, G.; Parekkat, V.; Rajashekar, D.; Tandon, N.

10.1101/2021.07.01.450660 — genomics — Posted on 2021-07-01

3911 The effects of introgression across thousands of quantitative traits revealed by gene expression in wild tomatoes

Hibbins, M. S.; Hahn, M. W.

10.1101/2021.07.01.450726 — evolutionary biology — Posted on 2021-07-01

3912 TGFβ2 regulates human trabecular meshwork cell contractility via ERK and ROCK pathways with distinct signaling crosstalk dependent on the culture substrate

Li, H.; Henty-Ridilla, J. L.; Ganapathy, P. S.; Herberg, S. S.

10.1101/2021.07.01.450718 — cell biology — Posted on 2021-07-01

3913 miR-155 exerts posttranscriptional control of autoimmune regulator (Aire) and tissue-restricted antigen genes in medullary thymic epithelial cells

Tanaka, P. P.; Oliveira, E. H.; Machado, M. C.; Duarte, M. J.; Assis, A. F.; Passos, G. A.

10.1101/2021.07.01.450769 — molecular biology — Posted on 2021-07-01

3914 CRISPR/Cas9 deletions induce adverse on-target genomic effects leading to functional DNA in human cells

Geng, K.; Merino, L. G.; Wedemann, L.; Martens, A.; Sobota, M.; Sondergaard, J. N.; White, R. J.; Kutter, C.

10.1101/2021.07.01.450727 — molecular biology — Posted on 2021-07-01

3915 Thiol-based mucolytics exhibit antiviral activity against SARS-CoV-2 through allosteric disulfide disruption in the spike glycoprotein

Shi, Y.; Zeida, A.; Edwards, C. E.; Mallory, M. L.; Sastre, S.; Machado, M. R.; Pickles, R. J.; Fu, L.; Liu, K.; Yang, J.; Baric, R. S.; Boucher, R. C.; Radi, R.; Carroll, K. S.

10.1101/2021.07.01.450701 — microbiology — Posted on 2021-07-01

3916 A Plasmodium falciparum lysophospholipase regulates fatty acid acquisition for membrane biogenesis to enable schizogonic asexual division

Sheokand, P. K.; Yamaryo-Botte, Y.; Thakur, V.; Banday, M. M.; Asad, M.; Botte, C. Y.; Mohmmed, A.

10.1101/2021.07.01.450682 — microbiology — Posted on 2021-07-01

3917 Lager yeast design through meiotic segregation of a fertile Saccharomyces cerevisiae x Saccharomyces eubayanus hybrid

Krogerus, K.; Magalhaes, F.; Castillo, S.; Peddinti, G.; Vidgren, V.; De Chiara, M.; Yue, J.-X.; Liti, G.; Gibson, B.

10.1101/2021.07.01.450509 — microbiology — Posted on 2021-07-01

3918 Modeling site-specific nucleotide biases affecting Himar1 transposon insertion frequencies in TnSeq datasets

Choudhery, S.; Brown, A. J.; Akusobi, C. D.; Rubin, E. J.; Sassetti, C. M.; Ioerger, T. R.

10.1101/2021.07.01.450749 — microbiology — Posted on 2021-07-01

3919 Conversion of spent CHO cell culture media waste to new fermentation feed efficiently supports production of recombinant protein by Escherichia coli

Lynch, C.; O'Connell, D. J.

10.1101/2021.07.01.450323 — microbiology — Posted on 2021-07-01

3920 Structural basis of membrane recognition of Toxoplasma gondii vacuole by Irgb6

Hamano, Y. S.; Sherif, A. A.; Pradipta, A.; Sasai, M.; Sakai, N.; Sakihama, Y.; Yamamoto, M.; Standley, D. M.; Nitta, R.

10.1101/2021.07.01.450801 — microbiology — Posted on 2021-07-01

3921 Ad26.COV2.S elicited neutralizing activity against Delta and other SARS-CoV-2 variants of concern

Jongeneelen, M.; Kaszas, K.; Veldman, D.; Huizingh, J.; van der Vlugt, R.; Schouten, T.; Zuijdgeest, D.; Uil, T.; van Roey, G.; Guimera, N.; Navis, M.; Bos, R.; Le Gars, M.; Sadoff, J.; Muchene, L.; Juraszek, J.; Langedijk, J. P.; Vogels, R.; Custers, J.; Schuitemaker, H.; Brandenburg, B.

10.1101/2021.07.01.450707 — immunology — Posted on 2021-07-01

3922 Macrophage Circadian Rhythms are Differentially Affected Based on Stimuli

Don, S. S. L.; Mas-Rosario, J. A.; Lin, H.-H.; Nguyen, M.; Taylor, S. R.; Farkas, M. E.

10.1101/2021.07.01.450771 — immunology — Posted on 2021-07-01

3923 Dendro-somatic synaptic inputs to ganglion cells violate receptive field and connectivity rules in the mammalian retina

Sedlacek, M.; Grimes, W.; Musgrove, M.; Nath, A.; Tian, H.; Hoon, M.; Rieke, F.; Singer, J. H.; Diamond, J. S.

10.1101/2021.07.01.450751 — neuroscience — Posted on 2021-07-01

3924 Oculomotor plant and neural dynamics suggest gaze control requires integration on distributed timescales

Miri, A.; Bhasin, B. J.; Aksay, E. R. F.; Tank, D. W.; Goldman, M. S.

10.1101/2021.06.30.450653 — neuroscience — Posted on 2021-07-01

3925 Reducing Synchronization to Increase Interest Improves Interpersonal Liking

Ravreby, I.; Shilat, Y.; Yeshurun, Y.

10.1101/2021.06.30.450608 — neuroscience — Posted on 2021-07-01

3926 Epigenetic mediation of AKT1 rs1130233 s effect on delta-9-tetrahydrocannabinol-induced medial temporal function during fear processing

Blest-Hopley, G.; Colizzi, M.; Prata, D.; Giampietro, V.; Brammer, M.; McGuire, P.; Bhattacharyya, S.

10.1101/2021.06.30.450484 — neuroscience — Posted on 2021-07-01

3927 Deciphering the tumor-specific immunopeptidome in vivo with genetically engineered mouse models

Jaeger, A. M.; Stopfer, L. E.; Sanders, E.; Sandel, D.; Freed-Pastor, W.; Rideout, W.; Naranjo, S.; Fessenden, T.; Winter, P. S.; Kohn, R.; Schenkel, J.; Shanahan, S.-L.; Shalek, A. K.; Spranger, S.; White, F.; Jacks, T.

10.1101/2021.06.30.450516 — cancer biology — Posted on 2021-07-01

3928 Classic genome-wide association methods are unlikely to identify causal variants in strongly clonal microbial populations.

Chen, P. E.; Shapiro, B. J.

10.1101/2021.06.30.450606 — genomics — Posted on 2021-07-01

3929 How dominant alleles influence progress towardspeciation by natural selection

Munzur, A. D.; Thompson, K. A.

10.1101/2021.06.30.450598 — evolutionary biology — Posted on 2021-07-01

3930 The influence of adaptation to life at high-altitude on condition dependent sexual shape and size dimorphism in Drosophila melanogaster

Pesevski, M.; Dworkin, I.

10.1101/2021.06.30.450630 — evolutionary biology — Posted on 2021-07-01

3931 Parallel genetic changes underlie integrated craniofacial traits in an adaptive radiation of trophic specialist pupfishes

St John, M. E.; Richards, E.; Dunker, J. C.; Romero, S.; Martin, C. H.

10.1101/2021.07.01.450661 — evolutionary biology — Posted on 2021-07-01

3932 Fungal effector SIB1 of Colletotrichum orbiculare has unique structural features and can suppress plant immunity in Nicotiana benthamiana

Zhang, R.; Isozumi, N.; Mori, M.; Okuta, R.; Singkaravanit-Ogawa, S.; Imamura, T.; Gan, P.; Shirasu, K.; Ohki, S.; Takano, Y.

10.1101/2021.07.01.450775 — microbiology — Posted on 2021-07-01

3933 In vitro Evaluation of Lytic Phages for Carbapenem-Resistant Klebsiella pneumoniae Isolates

Li, N.; Zeng, Y.; Zhang, Y.; Bao, R.; Hu, B.; Zhu, T.; Tan, D.

10.1101/2021.06.30.450654 — microbiology — Posted on 2021-07-01

3934 Inconsistent patterns of microbial diversity and composition between highly similar sequencing protocols: a case study with reef-building corals

Epstein, H. E.; Hernandez-Agreda, A.; Starko, S.; Baum, J. K.; Vega Thurber, R.

10.1101/2021.06.30.450656 — microbiology — Posted on 2021-07-01

3935 Genome-wide association study and functional validation implicates JADE1 in tauopathy

Farrell, K.; Kim, S.; Han, N.; Iida, M. A.; Gonzalez, E.; Otero-Garcia, M.; Walker, J.; Richardson, T.; Renton, A. E.; Andrews, S. J.; Fulton-Howard, B.; Humphrey, J.; Vialle, R. A.; Bowles, K. R.; Whitney, K.; Dangoor, D. K.; Marcora, E.; Hefti, M. M.; Casella, A.; Bhangale, T.; Hunkapiller, J.; Ayalon, G.; Graham, R.; Cherry, J. D.; Cortes, E.; Borukov, V.; McKee, A. C.; Stein, T. D.; Vonsattel, J. P.; Teich, A. F.; Gearing, M.; Glass, J.; Troncoso, J. C.; Frosch, M. P.; Hyman, B. T.; Dickson, D. W.; Murray, M. E.; Attems, J.; Flanagan, M. E.; Mao, Q.; Mesulam, M. M.; Weintraub, S.; Woltjer,

10.1101/2021.06.30.450599 — neuroscience — Posted on 2021-07-01

3936 Intrinsic Network Activity Reflects the Ongoing Experience of Chronic Pain

Jahn, P.; Deak, B.; Mayr, A.; Stankewitz, A.; Keeser, D.; Griffanti, L.; Witkovsky, V.; Irving, S.; Schulz, E.

10.1101/2021.06.30.450604 — neuroscience — Posted on 2021-07-01

3937 GABAA α Subunit Control of Hyperactive Behavior in Developing Zebrafish

Barnaby, W. W.; Dorman, H. E.; Nagarkar, A.; Perkins, M.; Teicher, G.; Trapani, J. G.; Downes, G. B.

10.1101/2021.07.01.450600 — neuroscience — Posted on 2021-07-01

3938 Intrinsic Network Connectivity Reflects the Cyclic Trajectory of Migraine Attacks

Stankewitz, A.; Schulz, E.

10.1101/2021.06.30.450593 — neuroscience — Posted on 2021-07-01

3939 Organization of the catecholaminergic system in the short-lived fish Nothobranchius furzeri

Borgonovo, J.; Ahumada-Galleguillos, P.; Onate-Ponce, A.; Allende-Castro, C.; Henny, P.; Concha, M. L.

10.1101/2021.06.30.450602 — neuroscience — Posted on 2021-07-01

3940 Two faces of perceptual awareness during the attentional blink: Gradual and discrete

Karabay, A.; Wilhelm, S. A.; de Jong, J.; Wang, J.; Martens, S.; Akyurek, E. G.

10.1101/769083 — neuroscience — Posted on 2021-07-01

3941 The Ventral Midline Thalamus Mediates Successful Deliberation by Coordinating Prefrontal and Hippocampal Neural Activity

Stout, J. J.; Hallock, H. L.; Adiraju, S.; Griffin, A. L.

10.1101/2021.06.30.450519 — neuroscience — Posted on 2021-07-01

3942 The versatile regulation of K2P channels by polyanionic lipids of the phosphoinositide (PIP2) and fatty acid metabolism (LC-CoA)

Riel, E. B.; Juers, B. C.; Cordeiro, S.; Musinszki, M. A.; Schewe, M.; Baukrowitz, T.

10.1101/2021.07.01.450694 — biophysics — Posted on 2021-07-01

3943 Inverse design of cholesterol attracting transmembrane helices reveals a paradoxical role of hydrophobic length

Methorst, J.; van Hilten, N.; Risselada, H. J.

10.1101/2021.07.01.450699 — biophysics — Posted on 2021-07-01

3944 High throughput measurement of Arabidopsis thaliana fitness traits using transfer learning

Wang, P.; Meng, F.; Donaldson, P.; Horan, S.; Panchy, N. L.; Vischulis, E.; Winship, E.; Conner, J. K.; Lehti-Shiu, M. D.; Shiu, S.-H.

10.1101/2021.07.01.450758 — bioinformatics — Posted on 2021-07-01

3945 Sigma70Pred: A highly accurate method for predicting sigma70 promoter in prokaryotic genome

Patiyal, S.; Singh, N.; Ali, M. Z.; Pundir, D. S.; Raghava, G. P. S.

10.1101/2021.06.29.450448 — bioinformatics — Posted on 2021-07-01

3946 Prolonging coagulant activity of factor Xa under hemophilic conditions by site-specific N-glycosylation of the surface-exposed autolysis loop

Bonde, A. C.; Lund, J.; Hansen, J. J.; Winther, J. R.; Zahn, S.; Tiainen, P.; Olsen, O. H.; Petersen, H. H.; Bjelke, J. R.

10.1101/2021.07.01.450767 — biochemistry — Posted on 2021-07-01

3947 Functional profiling of long intergenic non-coding RNAs in fission yeast

Rodriguez-Lopez, M.; Anver, S.; Cotobal, C.; Kamrad, S.; Malecki, M.; Correia-Melo, C.; Hoti, M.; Townsend, S.; Marguerat, S. B.; Pong, S.; Wu, M.; Montemayor, L.; Howell, M.; Ralser, M.; Bahler, J.

10.1101/2021.06.30.450572 — genetics — Posted on 2021-07-01

3948 An improved codon modeling approach for accurate estimation of the mutation bias

Latrille, T.; Lartillot, N.

10.1101/2021.06.30.450338 — evolutionary biology — Posted on 2021-07-01

3949 Partners in space: Discordant population structure between legume hosts and rhizobium symbionts in their native range

Riley, A.; Grillo, M.; Epstein, B.; Tiffin, P.; Heath, K.

10.1101/2021.06.30.449460 — evolutionary biology — Posted on 2021-07-01

3950 Rethinking habitat occupancy modeling and the role of diel activity in an anthropogenic world

Rivera, K.; Fidino, M.; Farris, Z.; Magle, S.; Murphy, A.; Gerber, B.

10.1101/2021.06.30.450589 — ecology — Posted on 2021-07-01

3951 Temporal and Spatial Niche Partitioning of Bumblebee Species (Apidae: Bombus) on a Himalayan Mountain

Moss, A. J.; Camilo, G. R.; Ren, Z.-X.; Bernhardt, P.

10.1101/2021.06.30.450469 — ecology — Posted on 2021-07-01

3952 The method of choice to knock-in large inserts via CRISPR

Marks, D.; Bachmann, L.; Gallego Villarejo, L.; Geidies, A.; Heinen, N.; Anstatt, J.; Mueller, T.

10.1101/2021.07.01.450700 — molecular biology — Posted on 2021-07-01

3953 Reduced Lytic Activity of Bacteriophages in Presence of Antibiotics Targeting Bacterial Protein Synthesis

Vashisth, M.; Yashveer, S.; Virmani, N.; Bera, B. C.; Vaid, R. K.; Anand, T.

10.1101/2021.06.30.450658 — microbiology — Posted on 2021-07-01

3954 High-density transposon mutagenesis in Mycobacterium abscessus identifies an essential penicillin-binding lipo-protein (PBP-lipo) involved in septal peptidoglycan synthesis and antibiotic sensitivity

Akusobi, C.; Benghomari, B. S.; Wolf, I. D.; Singhvi, S.; Zhu, J.; Ioerger, T. R.; Rubin, E. J.

10.1101/2021.07.01.450732 — microbiology — Posted on 2021-07-01

3955 Neuronal mechanism of a BK channelopathy in absence epilepsy and movement disorders

Dong, P.; Zhang, Y.; Mikati, M. A.; Cui, J.; Yang, H.

10.1101/2021.06.30.450615 — neuroscience — Posted on 2021-07-01

3956 Pain and the Emotional Brain: Affective Rather than Cognitive Processes Drive the Cortical Encoding of Pain

Mayr, A.; Stankewitz, A.; Irving, S.; Witkovsky, V.; Schulz, E.

10.1101/2021.06.30.450586 — neuroscience — Posted on 2021-07-01

3957 Long Term Study of Motivational and Cognitive Effects of Low-intensity Focused Ultrasound Neuromodulation in the Dorsal Striatum of Nonhuman Primates

Munoz, F.; Meaney, A.; Gross, A.; Liu, K.; Pouliopoulos, A. N.; Liu, D.; Konofagou, E. E.; Ferrera, V. P.

10.1101/2021.06.30.450605 — neuroscience — Posted on 2021-07-01

3958 BBB damage in aging causes brain iron deposits via astrocyte-neuron crosstalk and Hepc/Fpn1 pathway

Mezzanotte, M.; Ammirata, G.; Boido, M. M.; Stanga, S.; Roetto, A.

10.1101/2021.07.01.450665 — neuroscience — Posted on 2021-07-01

3959 Harnessing the Power of Sex Differences: What a Difference Ten Years Did Not Make

Rechlin, R. K.; Splinter, T. F.; Hodges, T. E.; Albert, A.; Galea, L.

10.1101/2021.06.30.450396 — neuroscience — Posted on 2021-07-01

3960 Sleep deprivation reduces the density of individual spine subtypes in a branch-specific fashion in CA1 neurons

Bolsius, Y. G.; Meerlo, P.; Kas, M. J.; Abel, T.; Havekes, R.

10.1101/2021.06.30.450529 — neuroscience — Posted on 2021-07-01

3961 Vitamin D modulates cortical transcriptome and behavioral phenotypes in an Mecp2 heterozygous Rett syndrome mouse model

Ribeiro, M. C.; MacDonald, J. L.

10.1101/2021.06.30.450587 — neuroscience — Posted on 2021-07-01

3962 Comprehensive transcriptomic analysis shows disturbed calcium homeostasis and deregulation of T lymphocyte apoptosis in inclusion body myositis

Johari, M.; Vihola, A.; Palmio, J.; Jokela, M.; Jonson, P. H.; Sarparanta, J.; Huovinen, S.; Savarese, M.; Hackman, P.; Udd, B.

10.1101/2021.06.30.450477 — neuroscience — Posted on 2021-07-01

3963 Inverse Density of Iba1 and Glutamine Synthetase Expressing Glia in Rat Inferior Colliculus

Orton, L. D.

10.1101/2021.06.30.450495 — neuroscience — Posted on 2021-07-01

3964 Dental caries in wild primates: interproximal cavities on anterior teeth

Towle, I.; Irish, J. D.; Sabbi, K.; Loch, C.

10.1101/2021.06.30.450645 — zoology — Posted on 2021-07-01

3965 Mechanistic model-driven exometabolomic characterisation of human dopaminergic neuronal metabolism

Preciat, G.; Moreno, E. L.; Wegrzyn, A.; Willacey, C. C. W.; Modamio, J.; Monteiro, F. L.; El Assal, D.; Schurink, A.; Oliveira, M. A. P.; Zhang, Z.; Cousins, B.; Zach, S.; Vempala, S.; Hengerer, B.; Harms, A.; Schwamborn, J. C.; Thiele, I.; Hankemeier, T.; Fleming, R. M.

10.1101/2021.06.30.450562 — systems biology — Posted on 2021-07-01

3966 Structural studies on cell wall biogenesis-I: A method to produce high-quality protoplasts from alga Micrasterias denticulata, an emerging model in plant biology

Selvaraj, M.

10.1101/2021.06.30.450603 — plant biology — Posted on 2021-07-01

3967 Small Vessel Diseases: 3D Characteristics of the Vasculature and White Matter

Saito, R.; Tainaka, K.; Nozaki, H.; Uemura, M.; Toyoshima, Y.; Suzuki, M.; Tanaka, M.; Hasegawa, A.; Abe, T.; Sato, A.; Hashidate, H.; Igarashi, S.; Koike, R.; Ueda, A.; Ueda, M.; Ando, Y.; Akazawa, K.; ONODERA, O.; Kakita, A.

10.1101/2021.06.30.450101 — pathology — Posted on 2021-07-01

3968 Proximity-dependent biotinylation to elucidate the interactome of TNK2 non-receptor tyrosine kinase

Tahir, R.; Madugundu, A. K.; Udainiya, S.; Cutler, J. A.; Renuse, S.; Wang, L.; Pearson, N. A.; Mitchell, C.; Mahajan, N.; Pandey, A.; Wu, X.

10.1101/2021.06.30.450607 — cancer biology — Posted on 2021-07-01

3969 The flying insect thoracic cuticle is heterogenous in structure and in thickness-dependent modulus gradation

Casey, C.; Yager, C.; Jankauski, M.; Heveran, C. M.

10.1101/2021.06.30.450643 — biophysics — Posted on 2021-07-01

3970 Benchmarking supervised signature-scoring methods for single-cell RNA sequencing data in cancer

Zheng, S.; Nighat, N.; Ye, Z.; Chen, Y.; Wang, X.

10.1101/2021.06.29.450404 — bioinformatics — Posted on 2021-07-01

3971 Optimal balancing of clinical factors in large scale clinical RNA-Seq studies

CHIANG, A. W. T.; Gazestani, V. H.; Altieri, M. G.; Courchesne, E.; Lewis, N. E.

10.1101/2021.06.30.450639 — bioinformatics — Posted on 2021-07-01

3972 Shortening of 3' UTRs in most cell types composing tumor tissues implicates alternative polyadenylation in protein metabolism

Burri, D.; Zavolan, M.

10.1101/2021.06.30.450496 — bioinformatics — Posted on 2021-07-01

3973 Monitoring the effects of chemical stimuli on live cells with metasurface-enhanced infrared reflection spectroscopy

Huang, S. H.; Li, J.; Fan, Z.; Delgado, R.; Shvets, G.

10.1101/2021.06.30.450584 — bioengineering — Posted on 2021-07-01

3974 In Situ Volumetric Imaging and Analysis of FRESH 3D Bioprinted Constructs Using Optical Coherence Tomography

Tashman, J. W.; Shiwarski, D. J.; Ruesch, A.; Lanni, F.; Kainerstorfer, J.; Feinberg, A. W.

10.1101/2021.06.30.450389 — bioengineering — Posted on 2021-07-01

3975 Network-Based Discovery of Opioid Use Vulnerability in Rats Using the Bayesian Stochastic Block Model

Allen, C.; Kuhn, B. N.; Cannella, N.; Crow, A. D.; Roberts, A. T.; Lunerti, V.; Ubaldi, M.; Hardiman, G.; Solberg Woods, L. C.; Ciccocioppo, R.; Kalivas, P. W.; Chung, D.

10.1101/2021.06.30.450568 — animal behavior and cognition — Posted on 2021-07-01

3976 Malignancy and NF-kB signalling strengthen coordination between the expression of mitochondrial and nuclear-encoded oxidative phosphorylation genes

Perez, M. F.; Sarkies, P.

10.1101/2021.06.30.450588 — genomics — Posted on 2021-07-01

3977 Evaluation of persistence and fate of ex vivo edited-HSC modified with donor template and Its role in correcting Sickle Cell Disease

Pattabhi, S.; Lotti, S. N.; Berger, M. P.; Rawlings, D. J.

10.1101/2021.06.30.450644 — genomics — Posted on 2021-07-01

3978 Genome of the parasitoid wasp Dinocampus coccinellae reveals extensive duplications, accelerated evolution, and independent origins of thelytokous parthenogeny and solitary behavior

Sethuraman, A.; Tovar, A.; Grenier, C.; Welch, W.; Arce, C.; Dettmers, R.; Skaggs, T.; Rothenberg, A.; Saisho, R.; Summerhays, B.; Cartmill, R.; Vasquez, Y.; Vansant, H.; Obrycki, J. J.

10.1101/2021.06.30.450623 — genomics — Posted on 2021-07-01

3979 Probing molecular specificity with deep sequencing and biophysically interpretable machine learning

Rube, H. T.; Rastogi, C.; Feng, S.; Kribelbauer, J. F.; Li, A.; Becerra, B.; Melo, L. A. N.; Do, B. V.; Li, X.; Adam, H. H.; Shah, N. H.; Mann, R. S.; Bussemaker, H. J.

10.1101/2021.06.30.450414 — genomics — Posted on 2021-07-01

3980 Identification of transcription termination defects at DNA hypomethylated transcription termination sites in DNA methyltransferase 3a-deficient vertebrates.

Shirai, M.; Nara, T.; Takahashi, H.; Takayama, K.; Chen, Y.; Hirose, Y.; Fujii, M.; Awazu, A.; Shimoda, N.; Kikuchi, Y.

10.1101/2021.06.30.450517 — genomics — Posted on 2021-07-01

3981 Complex Mutation Profiles in Mismatch Repair and Ribonucleotide Reductase Mutations Reveal Novel Repair Substrate Specificity of MutS Homolog (MSH) Complexes

Lamb, N. A.; Bard, J.; Loll-Krippleber, R.; Baryshnikova, A.; Brown, G. W.; Surtees, J. A.

10.1101/2021.06.30.450577 — genetics — Posted on 2021-07-01

3982 A role for worm cutl-24 in background- and parent-of-origin-dependent ER stress resistance

Wang, W.; Brem, R. B.; Garrison, J.; Flury, A.

10.1101/2021.07.01.450736 — genetics — Posted on 2021-07-01

3983 High-throughput variant detection using a color-mixing strategy in real-time PCR reactions

Xie, N. G.; Zhang, K.; Song, P.; Li, R.; Luo, J.; Zhang, D. Y.

10.1101/2021.06.30.450651 — genetics — Posted on 2021-07-01

3984 The histone chaperone FACT facilitates heterochromatin spreading through regulation of histone turnover and H3K9 methylation states

Murawska, M.; Greenstein, R. A.; Schauer, T.; Olsen, K. C. F.; Ng, H.; Ladurner, A. G.; Al-Sady, B.; Braun, S.

10.1101/2021.06.30.450523 — genetics — Posted on 2021-07-01

3985 daf-16/FOXO blocks adult cell fate in Caenorhabditis elegans dauer larvae via lin-41/TRIM71

Wirick, M. J.; Cale, A. R.; Smith, I. T.; Alessi, A. F.; Starostik, M. R.; Cuko, L.; Lalk, K.; Schmidt, M. N.; Olson, B. S.; Salomon, P. M.; Santos, A.; Schmitter-Sanchez, A.; Galagali, H.; Ranke, K. J.; Wolbert, P. A.; Knoblock, M. L.; Kim, J. K.; Karp, X.

10.1101/2021.06.30.450637 — genetics — Posted on 2021-07-01

3986 Fin Shape, Asymmetry, and Evolutionary Ecomorphology in Triggerfishes and Filefishes (Superfamily: Balistoidea)

George, A. B.; Westneat, M. W.

10.1101/2021.06.29.450391 — evolutionary biology — Posted on 2021-07-01

3987 A supergene in seaweed flies modulates male traits and female perception

Enge, S.; Merot, C.; Mozuraitis, R.; Apsegaite, V.; Bernatchez, L.; Martens, G. A.; Radziute, S.; Pavia, H.; Berdan, E. L.

10.1101/2021.06.30.450538 — evolutionary biology — Posted on 2021-07-01

3988 Twisting to freedom: The evolution of copulation termination techniques across 48 species of sepsids (Diptera, Sepsidae)

Tuan, M. J. M.; Araujo, D. P.; Puniamoorthy, N.; Woodford, J. M.; Meier, R.

10.1101/2021.06.30.450518 — evolutionary biology — Posted on 2021-07-01

3989 Does Communal Breeding Promote an Increase in Social Immunity in Burying Beetles? A Test Case with Nicrophorus Defodiens

Suswaram, M. R.; Belk, M.; Creighton, C.

10.1101/2021.06.30.450575 — ecology — Posted on 2021-07-01

3990 Microbial community composition of translocated ancient woodland soil: a case study

Borchers, N.; Hannam, J.; Pawlett, M.

10.1101/2021.06.30.450580 — ecology — Posted on 2021-07-01

3991 Mega-fire in Redwood Tanoak Forest Reduces Bacterial and Fungal Richness and Selects for Pyrophilous Taxa and Traits that are Phylogenetically Conserved

Enright, D. J.; Frangioso, K. M.; Isobe, K.; Rizzo, D. M.; Glassman, S. I.

10.1101/2021.06.30.450634 — ecology — Posted on 2021-07-01

3992 Life history mediates the trade-offs among different components of demographic resilience

Capdevila, P.; Stott, I.; Cant, J.; Beger, M.; Rowlands, G.; Grace, M.; Salguero-Gomez, R.

10.1101/2021.06.30.450480 — ecology — Posted on 2021-07-01

3993 Mitotic chromosome condensation requires phosphorylation of the centromeric protein KNL-2 in C. elegans

Wenda, J. M.; Prosee, R. F.; Gabus, C.; Steiner, F. A.

10.1101/2021.07.01.450752 — cell biology — Posted on 2021-07-01

3994 A transferable IncC-IncX3 hybrid plasmid co-carrying blaNDM-4, tet(X4), and tmexCD3-toprJ3 confers resistance to carbapenem and tigecycline

Hirabayashi, A.; Dao, T. D.; Takemura, T.; Hasebe, F.; Trang, L. T.; Thanh, N. H.; Tran, H. H.; Shibayama, K.; Kasuga, I.; Suzuki, M.

10.1101/2021.06.30.450641 — microbiology — Posted on 2021-07-01

3995 Synthetic dual-function RNA reveals features necessary for target regulation

Aoyama, J. J.; Raina, M.; Storz, G.

10.1101/2021.06.30.450655 — microbiology — Posted on 2021-07-01

3996 ICER controls HIV-1 infection and replication in elite controllers

Luo, Z.; Li, M.; Li, T.; Lv, Z.; Ye, Z.; Cisneros, W. J.; Zhang, J.; Yuan, L.; Hultquist, J. F.; Migueles, S.; Zhu, J.; Jiang, W.

10.1101/2021.06.30.450567 — immunology — Posted on 2021-07-01

3997 Prenatal alcohol exposure disrupts hippocampal sharp-wave ripple-associated spike dynamics

Harvey, R. E.; Berkowitz, L. E.; Savage, D. D.; Clark, B. J.

10.1101/2021.06.29.450435 — neuroscience — Posted on 2021-07-01

3998 Early neuroadaptations to an obesogenic diet identify the schizophrenia-related ErbB4 receptor in obesity-induced hippocampal abnormalities

Vega-Torres, J. D.; Ontiveros-Angel, P.; Terrones, E.; Stuffle, E. C.; Solak, S.; Tyner, E.; Oropeza, M.; Dela Pena, I.; Obenaus, A.; Ford, B. D.; Figueroa, J. D.

10.1101/2021.06.30.450398 — neuroscience — Posted on 2021-07-01

3999 Genomic Modules and Intramodular Network Convergency of Susceptibility and Resilience in Multimodeled Stress in Male Mice

Marrocco, J.; Caradonna, S. G.; Zhang, T.-Y.; O'Toole, N.; Shen, M.-J.; Khalil, H.; Einhorn, N.; Wen, X.; Parent, C.; Lee, F. S.; Akil, H.; McEwen, B.; Meaney, M. J.

10.1101/2021.06.30.450390 — neuroscience — Posted on 2021-07-01

4000 Deficiency of the ywhaz gene, involved in neurodevelopmental disorders, alters brain activity and behaviour in zebrafish

Anton-Galindo, E.; Dalla Vecchia, E.; Orlandi, J. G.; Castro, G.; Gualda, E.; Loza-Alvarez, P.; Aguado, F.; Norton, W. H.; Cormand, B.; Fernandez-Castillo, N.

10.1101/2021.06.30.450513 — neuroscience — Posted on 2021-07-01

4001 Individually Unique Dynamics of Cortical Connectivity Reflect the Ongoing Intensity of Chronic Pain

Mayr, A.; Jahn, P.; Deak, B.; Stankewitz, A.; Devulapally, V.; Witkovsky, V.; Dietrich, O.; Schulz, E.

10.1101/2021.06.30.450553 — neuroscience — Posted on 2021-07-01

4002 BOLD fMRI signals of visual white matter encode visuotopic information and predict effective connectivity between visual areas

Wang, H.; Wang, X.; Wang, Y.; Zhang, D.; Zhou, Y.; Qiu, B.; Zhang, P.

10.1101/2021.06.30.450520 — neuroscience — Posted on 2021-07-01

4003 A model of rapid homeostatic plasticity accounts for hidden, long-lasting changes in a neuronal circuit after exposure to high potassium.

Rue, M. C. P.; Alonso, L. M.; Marder, E.

10.1101/2021.07.01.450770 — neuroscience — Posted on 2021-07-01

4004 Intrinsic Network Activity Reflects the Fluctuating Experience of Tonic Pain

Deak, B.; Eggert, T.; Mayr, A.; Stankewitz, A.; Filippopulos, F.; Jahn, P.; Witkovsky, V.; Straube, A.; Schulz, E.

10.1101/2021.06.30.450591 — neuroscience — Posted on 2021-07-01

4005 Characterization of the Brassica napus flavonol synthase gene family reveals bifunctional flavonol synthases

Schilbert, H. M.; Schoene, M.; Baier, T.; Busche, M.; Viehoever, P.; Weisshaar, B.; Holtgraewe, D.

10.1101/2021.06.30.450533 — plant biology — Posted on 2021-07-01

4006 A 3D gene expression atlas of the floral meristem based on spatial reconstruction of single nucleus RNA sequencing data

Neumann, M.; Xu, X.; Smaczniak, C.; Schumacher, J.; Yan, W.; Greb, T.; Bluthgen, N.; Jonsson, H.; Traas, J.; Kaufmann, K.; Muino, J. M.

10.1101/2021.06.30.450319 — plant biology — Posted on 2021-07-01

4007 Determination of the Optical Properties of Thylakoid Membranes from Whole Leaf Reflectance Measurements Using a Capacitor and Unbound Electron Model

Muttiah, R. S.

10.1101/2021.06.30.450215 — plant biology — Posted on 2021-07-01

4008 Integrative analysis of the shikonin metabolic network identifies new gene connections and reveals evolutionary insight into shikonin biosynthesis

Suttiyut, T.; Auber, R. P.; Ghaste, M.; Kane, C. N.; McAdam, S. A.; Wisecaver, J. H.; Widhalm, J. R.

10.1101/2021.06.30.450579 — plant biology — Posted on 2021-07-01

4009 Susceptibility to diet induced obesity at thermoneutral conditions is independent of UCP1

Dieckmann, S.; Strohmeyer, A.; Willershaeuser, M.; Maurer, S.; Wurst, W.; Marschall, S.; Hrabe de Angelis, M.; Kuehn, R.; Worthmann, A.; Fuh, M. M.; Heeren, J.; Koehler, N.; Pauling, J.; Klingenspor, M.

10.1101/2021.06.30.450595 — physiology — Posted on 2021-07-01

4010 Toxicological profile of umbilical cord blood-derived small extracellular vesicles

Rodrigues, S. C.; Cardoso, R. M. S.; Gomes, C. F.; Duarte, F. V.; Freire, P. C.; Neves, R.; Simoes-Correia, J.

10.1101/2021.06.30.450343 — pharmacology and toxicology — Posted on 2021-07-01

4011 Conversion of cancer-associated fibroblasts from pro- to antitumor improves the sensitivity of pancreatic cancer to chemotherapeutics

Iida, T.; Mizutani, Y.; Esaki, N.; Ponik, S. M.; Burkel, B. M.; Weng, L.; Kuwata, K.; Masamune, A.; Ishihara, S.; Haga, H.; Kataoka, K.; Mii, S.; Shiraki, Y.; Ishikawa, T.; Ohno, E.; Kawashima, H.; Hirooka, Y.; Fujishiro, M.; Takahashi, M.; Enomoto, A.

10.1101/2021.06.29.450327 — cancer biology — Posted on 2021-07-01

4012 Intratumoral Heterogeneity Promotes Collective Cancer Invasion Through NOTCH1 Variation

Torab, P.; Yan, Y.; Ahmed, M.; Yamashita, H.; Warrick, J.; Raman, J.; DeGraff, D. J.; Wong, P.

10.1101/2021.06.30.450540 — cancer biology — Posted on 2021-07-01

4013 Evaluation of FRET X for Single-Molecule Protein Fingerprinting

de Lannoy, C.; Filius, M.; van Wee, R.; Joo, C.; de Ridder, D.

10.1101/2021.06.30.450512 — biophysics — Posted on 2021-07-01

4014 Improved estimation of cell type-specific gene expression through deconvolution of bulk tissues with matrix completion

Wang, W.; Yao, J.; Wang, Y.; Zhang, C.; Tao, W.; Zou, J.; Ni, T.

10.1101/2021.06.30.450493 — bioinformatics — Posted on 2021-07-01

4015 spiralize: an R Package for Visualizing Data on Spirals

Gu, Z.; Huebschmann, D.

10.1101/2021.06.30.450482 — bioinformatics — Posted on 2021-07-01

4016 The Genome Sequence Archive Family: Towards Explosive Data Growth and Diverse Data Types

Chen, T.; Chen, X.; Zhang, S.; Zhu, J.; Tang, B.; Wang, A.; Dong, L.; Zhang, Z.; Yu, C.; Sun, Y.; Chi, L.; Chen, H.; Zhai, S.; Sun, Y.; Lan, L.; Zhang, X.; Xiao, J.; Bao, Y.; Wang, Y.; Zhang, Z.; Zhao, W.

10.1101/2021.06.29.449849 — bioinformatics — Posted on 2021-07-01

4017 PCaDB - a comprehensive and interactive database for transcriptomes from prostate cancer population cohorts

Li, R.; Jia, Z.

10.1101/2021.06.29.449134 — bioinformatics — Posted on 2021-07-01

4018 Capturing hidden regulation based on noise change of gene expression level from single cell RNA-seq in yeast

Itoh, T.; Makino, T.

10.1101/2021.06.29.450440 — bioinformatics — Posted on 2021-07-01

4019 miRNAFinder: A Comprehensive Web Resource for Plant Pre-microRNA Classification

Lokuge, S.; Jayasundara, S.; Ihalagedara, P.; Herath, D.; Kahanda, I.

10.1101/2021.06.30.450478 — bioinformatics — Posted on 2021-07-01

4020 High-throughput single-cell TCR - pMHC dissociation rate measurements performed by an autonomous microfluidic cellular processing unit

Jammes, F.; Schmidt, J.; Coukos, G.; Maerkl, S. J.

10.1101/2021.06.30.450499 — bioengineering — Posted on 2021-07-01

4021 Glutathione synthetase overexpression in Acidithiobacillus ferrooxidans improves halotolerance of iron oxidation

Inaba, Y.; West, A. C.; Banta, S.

10.1101/2021.06.29.450459 — bioengineering — Posted on 2021-07-01

4022 Epigenetic regulation clocks the multigenerational olfactory imprinting in C. elegans

Garcia, M. E.; Fernandes de Abreu, D. A.; Gruet, A.; Blanchard, M.-P.; Baranger, K.; Clovis, Y.; Feron, F.; Remy, J.-J.

10.1101/2021.06.30.449753 — animal behavior and cognition — Posted on 2021-07-01

4023 Predicting trait phenotypes from knowledge of the topology of gene networks

Beatty, A.; Winkler, C. R.; Hagen, T.; Cooper, M.

10.1101/2021.06.29.450449 — genetics — Posted on 2021-07-01

4024 RFU derived LRs for activity level assignments usingBayesian Networks

Gill, P.; Bleka, O.; Fonnelop, A. E.

10.1101/2021.06.30.450487 — genetics — Posted on 2021-07-01

4025 Penetrance estimation of SORL1 loss-of-function variants using a family-based strategy adjusted on APOE genotypes suggest a non-monogenic inheritance

Schramm, C.; Charbonnier, C.; Zarea, A.; Lacour, M.; Wallon, D.; CNRMAJ collaborators, ; Boland, A.; Deleuze, J.-F.; Olaso, R.; Alarcon, F.; Campion, D.; Nuel, G.; Nicolas, G.

10.1101/2021.06.30.450554 — genetics — Posted on 2021-07-01

4026 Protracted speciation under the state-dependent speciation and extinction approach

Hua, X.; Herdha, T.; Burden, C.

10.1101/2021.06.29.450466 — evolutionary biology — Posted on 2021-07-01

4027 Toward an understanding of the chemical ecology of alternative reproductive tactics in the bulb mite (Rhizoglyphus robini)

Zeeman, A. N.; Smallegange, I. M.; Burdfield-Steel, E.; Groot, A. T.; Stewart, K. A.

10.1101/2021.06.30.450527 — evolutionary biology — Posted on 2021-07-01

4028 Sensitive Detection of Site-wise Convergent Evolution in Large Protein Alignments with ConDor

Morel, M.; Lemoine, F.; Gascuel, O.

10.1101/2021.06.30.450558 — evolutionary biology — Posted on 2021-07-01

4029 Promoting long-term forest landscape resilience in the Lake Tahoe basin

Abelson, E. S.; Reynolds, K. M.; White, A. M.; Long, J. W.; Maxwell, C.; Manley, P. N.

10.1101/2021.06.29.450434 — ecology — Posted on 2021-07-01

4030 Rapid generation of homozygous fluorescent knock-in human cells using CRISPR/Cas9 genome editing and validation by automated imaging and digital PCR screening

Kueblbeck, M.; Callegari, A.; Serrano-Solano, B.; Ellenberg, J.

10.1101/2021.06.23.449557 — cell biology — Posted on 2021-07-01

4031 Epigenetic regulation of frog innate immunity: Discovery of frog microRNAs associated with antiviral responses and ranavirus infection using a Xenopus laevis skin epithelial-like cell line

Todd, L. A.; Bui-Marinos, M. P.; Katzenback, B. A.

10.1101/2021.06.29.450442 — immunology — Posted on 2021-07-01

4032 Distinct repertoire expansion patterns during affinity maturation of antigen responding camelid-derived single-domain VHH antibody

Matsuda, T.; Akazawa-Ogawa, Y.; Komaba, L.-K.; Kiyose, N.; Miyazaki, N.; Mizuguchi, Y.; Fukuta, T.; Ito, Y.; Hagihara, Y.

10.1101/2021.06.29.449501 — immunology — Posted on 2021-07-01

4033 PET imaging studies to investigate functional expression of mGluR2 using mG2P001

Yuan, G.; Dhaynaut, M.; Guehl, N. J.; Ramesh, N.; Moon, S.-H.; Qu, X.; Poutiainen, P.; Afshar, S.; El Fakhri, G.; Brownell, A.-L.; Normandin, M. D.

10.1101/2021.06.29.450406 — neuroscience — Posted on 2021-07-01

4034 All-optical interrogation of neural circuits in behaving mice

Russell, L. E.; Dalgleish, H. W. P.; Nutbrown, R.; Gauld, O.; Herrmann, D.; Fisek, M.; Packer, A.; Hausser, M.

10.1101/2021.06.29.450430 — neuroscience — Posted on 2021-07-01

4035 Chemogenetic activation of midline thalamic nuclei fails to ameliorate memory deficits in two mouse models of Alzheimer's disease

Kohli, S.; Andrianova, L.; Margetts-Smith, G.; Brady, E.; Craig, M. T.

10.1101/2021.06.30.450500 — neuroscience — Posted on 2021-07-01

4036 Reliability of decision-making and reinforcement learning computational parameters

Mkrtchian, A.; Valton, V.; Roiser, J. P.

10.1101/2021.06.30.450026 — neuroscience — Posted on 2021-07-01

4037 Electrical synapse asymmetry results from, and masks, neuronal heterogeneity

Haas, J.; Mendoza, A.

10.1101/2021.06.30.450525 — neuroscience — Posted on 2021-07-01

4038 Epileptiform GluN2B-driven excitation in hippocampus as a therapeutic target against temporal lobe epilepsy

Gorlewicz, A.; Pijet, B.; Orlova, K.; Kaczmarek, L.; Knapska, E.

10.1101/2021.06.30.450508 — neuroscience — Posted on 2021-07-01

4039 A novel post-translational proteomics platform identifies neurite outgrowth impairments in Parkinson's disease GBA-N370S dopamine neurons

Bogetofte, H.; Ryan, B. J.; Jensen, P.; Vergoossen, D. L. E.; Bogetofte Barnkob, M.; Kiani, L.; Chughtai, U.; Brandes, J.; Vowles, J. J.; Bunn, F.; Kilfeather, P.; Fernandes, H. J. R.; Caffrey, T.; Meyer, M.; Cowley, S. A.; Larsen, M. R.; Wade-Martins, R.

10.1101/2021.06.30.450333 — neuroscience — Posted on 2021-07-01

4040 Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice

Cudalbu, C.; Bady, P.; Lai, M.; Xin, L.; Gusyatiner, O.; Hamou, M.-F.; Lepore, M.; Brouland, J.-P.; Daniel, R. T.; Hottinger, A.; Hegi, M. E.

10.1101/2021.06.29.450408 — cancer biology — Posted on 2021-07-01

4041 Alevin-fry unlocks rapid, accurate, and memory-frugal quantification of single-cell RNA-seq data

He, D.; Zakeri, M.; Sarkar, H.; Soneson, C.; Srivastava, A.; Patro, R.

10.1101/2021.06.29.450377 — bioinformatics — Posted on 2021-07-01

4042 Trends and Gaps on Philippine Scombrid Research: A bibliometric analysis

Gadut, J.-A.; Deocaris, C. C.; Alinsug, M. V.

10.1101/2021.06.30.450467 — bioinformatics — Posted on 2021-07-01

4043 High-Potency Polypeptide-based Inhibition of Enveloped-virus Glycoproteins

Ma, J.; Campos Acevedo, A.; Wang, Q.

10.1101/2021.04.05.438537 — biochemistry — Posted on 2021-07-01

4044 Frequent female song in blue tits: behavioural context suggests a role in intrasexual competition

Sierro, J.; de Kort, S. R.; Riebel, K.; Hartley, I. R.

10.1101/2021.07.01.450672 — animal behavior and cognition — Posted on 2021-07-01

4045 A genetic toolkit for studying transposon control in the Drosophila melanogaster ovary

Brennecke, J.; ElMaghraby, M. F.; Laszlo, T.; Senti, K. A.; Meixner, K.

10.1101/2021.06.29.450424 — genetics — Posted on 2021-07-01

4046 Global distribution and richness of Armillaria species inferred from public databases and amplicon sequencing datasets

Koch, R. A.; Herr, J. R.

10.1101/2021.06.29.450419 — evolutionary biology — Posted on 2021-07-01

4047 Design, synthesis, and characterization of mG2P026 as a high contrast PET imaging ligand for metabotropic glutamate receptor 2

Yuan, G.; Dhaynaut, M.; Guehl, N. J.; Afshar, S.; Huynh, D.; Moon, S.-H.; Iyengar, S.; Kang, H. J.; Ondrechen, M. J.; El Fakhri, G.; Normandin, M. D.; Brownell, A.-L.

10.1101/2021.06.29.450249 — neuroscience — Posted on 2021-07-01

4048 Transcriptional profiling of sequentially generated septal neuron fates

Harwell, C. C.; Turrero Garcia, M.; Stegmann, S. K.; Lacey, T.; Reid, C. M.; Hrvatin, S.; Weinreb, C.; Adam, M. A.; Nagy, M. A.

10.1101/2021.06.29.450296 — neuroscience — Posted on 2021-07-01

4049 Prefrontal stimulation prior to motor sequence learning alters multivoxel patterns in the striatum and the hippocampus

Gann, M. A.; King, B. R.; Dolfen, N.; Veldman, M. P.; Davare, M.; Swinnen, S. P.; Mantini, D.; Robertson, E. M.; Albouy, G.

10.1101/2021.07.01.450671 — neuroscience — Posted on 2021-07-01

4050 Optogenetic tools for public goods control in Saccharomyces cerevisiae

Moreno Morales, N.; Patel, M. T.; Stewart, C. J.; Sweeney, K.; McClean, M. N.

10.1101/2021.06.28.450270 — bioengineering — Posted on 2021-07-01

4051 Mapping of the fibrinogen-binding site on the staphylocoagulase C-terminal repeat region

Maddur, A. A.; Voehler, M. W.; Panizzi, P.; Meiler, J.; Bock, P. E.; Verhamme, I. M.

10.1101/2021.06.29.450373 — biochemistry — Posted on 2021-07-01

4052 Specialization of chromatin-bound nuclear pore complexes promotes yeast aging

Meinema, A. C.; Aspert, T.; Lee, S. S.; Charvin, G.; Barral, Y.

10.1101/2021.06.28.450139 — cell biology — Posted on 2021-07-01

4053 B1-type cyclins control microtubule organization during cell division in Arabidopsis

Motta, M. R.; Zhao, X.; Pastuglia, M.; Belcram, K.; Roodbarkelari, F.; Komaki, M.; Harashima, H.; Komaki, S.; Bulankova, P.; Heese, M.; Riha, K.; Bouchez, D.; Schnittger, A.

10.1101/2021.06.29.450310 — cell biology — Posted on 2021-07-01

4054 Blocking mitophagy does not improve fuel ethanol production in Saccharomyces cerevisiae

Eliodorio, K. P.; de Gois e Cunha, G. C.; White, B. A.; Patel, D. H.; Zhang, F.; Hettema, E.; Basso, T. O.; Gombert, A.; Raghavendran, V.

10.1101/2021.06.29.450456 — microbiology — Posted on 2021-07-01

4055 Logical modeling: Combining manual curation and automated parameterization to predict drug synergies

Flobak, A.; Zobolas, J.; Vazquez, M.; Steigedal, T. S.; Thommesen, L.; Grislingas, A.; Niederdorfer, B.; Folkesson, E.; Kuiper, M.

10.1101/2021.06.28.450165 — systems biology — Posted on 2021-07-01

4056 An open-access volume electron microscopy atlas of whole cells and tissues

Xu, C. S.; Pang, S.; Shtengel, G.; Müller, A.; Ritter, A. T.; Hoffman, H. K.; Takemura, S.-y.; Lu, Z.; Pasolli, H. A.; Iyer, N.; Chung, J.; Bennett, D.; Weigel, A. V.; Freeman, M.; van Engelenburg, S. B.; Walther, T. C.; Farese, R. V.; Lippincott-Schwartz, J.; Mellman, I.; Solimena, M.; Hess, H.

10.1101/2020.11.13.382457 — cell biology — Posted on 2021-07-01

4057 Nanopore sequencing reveals endogenous NMD-targeted isoforms in human cells

Karousis, E. D.; Gypas, F.; Zavolan, M.; Muehlemann, O.

10.1101/2021.04.30.442116 — molecular biology — Posted on 2021-07-01

4058 Mycobacterium tuberculosis SufR Responds to Nitric oxide via its 4Fe-4S cluster and Regulates Fe-S cluster Biogenesis for Persistence in Mice

Anand, K.; Tripathi, A.; Shukla, K.; Malhotra, N.; Jamithireddy, A.; Jha, R. K.; Chaudhury, S. N.; Rajmani, R. S.; Ramesh, A.; Nagaraja, V.; Gopal, B.; Nagaraju, G.; Seshasayee, A. S. N.; Singh, A.

10.1101/2020.08.10.245365 — microbiology — Posted on 2021-07-01

4059 A simplified method for CRISPR-Cas9 engineering of Bacillus subtilis

Sachla, A. J.; Alfonso, A. J.; Helmann, J. D.

10.1101/2021.06.29.450457 — microbiology — Posted on 2021-07-01

4060 Optimisation of functional network resources when learning behavioural strategies for performing complex tasks

Daws, R. E.; Scott, G.; Soreq, E.; Leech, R.; Hellyer, P.; Hampshire, A.

10.1101/2020.06.17.156570 — neuroscience — Posted on 2021-07-01

4061 Probing machine-learning classifiers using noise, bubbles, and reverse correlation

Thoret, E.; Andrillon, T.; Leger, D.; Pressnitzer, D.

10.1101/2020.06.22.165688 — neuroscience — Posted on 2021-07-01

4062 Optimism and pessimism in optimised replay

Antonov, G.; Gagne, C.; Eldar, E.; Dayan, P.

10.1101/2021.04.27.441454 — neuroscience — Posted on 2021-07-01

4063 Synaptic targets of photoreceptors specialized to detect color and skylight polarization in Drosophila

Kind, E.; Longden, K. D.; Nern, A.; Zhao, A.; Sancer, G.; Flynn, M.; Laughland, C.; Gezahegn, B.; Ludwig, H.; Thomson, A.; Obrusnik, T.; Alarcon, P. G.; Dionne, H.; Bock, D. D.; Rubin, G. M.; Reiser, M. B.; Wernet, M. F.

10.1101/2021.05.17.444480 — neuroscience — Posted on 2021-07-01

4064 Rare long-range cortical connections enhance information processing

Deco, G.; Sanz Perl, Y.; Vuust, P.; Tagliazucchi, E.; Kennedy, H.; Kringelbach, M. L.

10.1101/2021.02.08.430236 — neuroscience — Posted on 2021-07-01

4065 Different underlying mechanisms for high and low arousal in probabilistic learning in humans

Ciria, L. F.; Suarez-Pinilla, M.; Williams, A. G.; Jagannathan, S. R.; Sanabria, D.; Bekinschtein, T. A.

10.1101/2021.02.26.431959 — neuroscience — Posted on 2021-07-01

4066 DiversityScanner: Robotic discovery of small invertebrates with machine learning methods

Wuehrl, L.; Pylatiuk, C.; Giersch, M.; Lapp, F.; von Rintelen, T.; Balke, M.; Schmidt, S.; Cerretti, P.; Meier, R.

10.1101/2021.05.17.444523 — zoology — Posted on 2021-07-01

4067 Rossmann-toolbox: a deep learning-based protocol for the prediction and design of cofactor specificity in Rossmann-fold proteins

Kaminski, K.; Ludwiczak, J.; Jasinski, M.; Bukala, A.; Madaj, R.; Szczepaniak, K.; Dunin-Horkawicz, S.

10.1101/2021.05.05.440912 — bioinformatics — Posted on 2021-07-01

4068 Validation and classification of RNA binding proteins identified by mRNA interactome capture

Vaishali, V.; Dimitrova-Paternoga, L.; Haubrich, K.; Sun, M.; Ephrussi, A.; Hennig, J.

10.1101/2021.02.02.429302 — biochemistry — Posted on 2021-07-01

4069 Primary saturation of α,β-unsaturated carbonyl containing fatty acids does not abolish electrophilicity

Snyder, N. W.; O'Brien, J.; Singh, B.; Buchan, G.; Arroyo, A. D.; Liu, X.; Bostwick, A.; Varner, E. L.; Angajala, A.; Sobol, R. W.; Blair, I. A.; Mesaros, C. A.; Wendell, S. G.

10.1101/2020.09.24.311985 — biochemistry — Posted on 2021-07-01

4070 Adaptive introgression and de novo mutations increase access to novel fitness peaks on the fitness landscape during a vertebrate adaptive radiation

Patton, A. H.; Richards, E.; Gould, K. J.; Buie, L. K.; Martin, C. H.

10.1101/2021.07.01.450666 — evolutionary biology — Posted on 2021-07-01

4071 Spike protein cleavage-activation mediated by the SARS-CoV-2 P681R mutation: a case-study from its first appearance in variant of interest (VOI) A.23.1 identified in Uganda

Frazier, L.; Lubinski, B.; Tang, T.; Daniel, S.; Jaimes, J. A.; Whittaker, G.

10.1101/2021.06.30.450632 — microbiology — Posted on 2021-07-01

4072 Probabilistic skeletons endow brain-like neural networks with innate computing capabilities

Stoeckl, C.; Lang, D.; Maass, W.

10.1101/2021.05.18.444689 — neuroscience — Posted on 2021-07-01

4073 Lipid-mediated Association of the Slg1 Transmembrane Domains in Yeast Plasma Membranes

Alavizargar, A.; Elting, A.; Wedlich Soeldner, R.; Heuer, A.

10.1101/2021.06.29.450341 — biophysics — Posted on 2021-07-01

4074 Nuclear and plastid phylogenomic analyses provide insights into the biogeography and reticulate evolution of the Sino-Japanese disjunctive Diabelia (Caprifoliaceae)

Ke, X.; Morales-Briones, D. F.; Wang, H.; Sun, Q.; Jacob, L. B.; Wen, J.; Wang, H.

10.1101/2021.05.31.446416 — evolutionary biology — Posted on 2021-07-01

4075 The Exon Junction Complex Core Represses Caner-specific Mature mRNA Re-splicing: A Potential Key Role in Terminating Splicing

Otani, Y.; Fujita, K.-i.; Kameyama, T.; Mayeda, A.

10.1101/2021.04.01.438154 — molecular biology — Posted on 2021-07-01

Archive, 2021-07