date is 2020-08
Select an archive month  
May 2025
April 2025
March 2025
February 2025
January 2025
December 2024
November 2024
October 2024
September 2024
August 2024
July 2024
June 2024
May 2024
April 2024
March 2024
February 2024
January 2024
December 2023
November 2023
October 2023
September 2023
August 2023
July 2023
June 2023
May 2023
April 2023
March 2023
February 2023
January 2023
December 2022
November 2022
October 2022
September 2022
August 2022
July 2022
June 2022
May 2022
April 2022
March 2022
February 2022
January 2022
December 2021
November 2021
October 2021
September 2021
August 2021
July 2021
June 2021
May 2021
April 2021
March 2021
February 2021
January 2021
December 2020
November 2020
October 2020
September 2020
August 2020
July 2020
June 2020
May 2020
April 2020
March 2020
February 2020
January 2020
December 2019
November 2019
October 2019
September 2019
August 2019
July 2019
June 2019
May 2019
April 2019
March 2019
February 2019
January 2019
December 2018
November 2018
October 2018
September 2018
August 2018
July 2018
June 2018
May 2018
April 2018
March 2018
February 2018
January 2018
December 2017
November 2017
October 2017
September 2017
August 2017
July 2017
June 2017
May 2017
April 2017
March 2017
February 2017
January 2017
December 2016
November 2016
October 2016
September 2016
August 2016
July 2016
June 2016
May 2016
April 2016
March 2016
February 2016
January 2016
December 2015
November 2015
October 2015
September 2015
August 2015
July 2015
June 2015
May 2015
April 2015
March 2015
February 2015
January 2015
December 2014
November 2014
October 2014
September 2014
August 2014
July 2014
June 2014
May 2014
April 2014
March 2014
February 2014
January 2014
December 2013
November 2013

Archive, 2020-08

4 Transcriptional kinetic synergy: a complex landscape revealed by integrating modelling and synthetic biology
Martinez Corral, R.; Park, M.; Biette, K.; Friedrich, D.; Scholes, C.; Khalil, A. S.; Gunawardena, J.; DePace, A.
10.1101/2020.08.31.276261 — systems biology — Posted on 2020-08-31
6 Role of hemocytes in the regeneration of germline stem cells in Drosophila
Varga, V. B.; Szikszai, F.; Szinyakovics, J.; Manzeger, A.; Puska, G.; Kovacs, T.; Vellai, T.
10.1101/2020.08.31.275255 — cell biology — Posted on 2020-08-31
10 INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia
Tsai, A. P.-Y.; Lin, P. B.-C.; Dong, C.; Moutinho, M.; Casali, B. T.; Liu, Y.; Lamb, B. T.; Landreth, G. E.; Oblak, A. L.; Nho, K.
10.1101/2020.08.31.276444 — neuroscience — Posted on 2020-08-31
14 CIP2A interacts with TopBP1 and is selectively essential for DNA damage-induced basal-like breast cancer tumorigenesis
Laine, A.; Nagelli, S.; Farrington, C.; Butt, U.; Cvrljevic, A.; Vainonen, J.; Gronroos, T.; Gautam, P.; Khan, S.; Sihto, H.; Qiao, X.; Connolly, D.; Kronqvist, P.; Maurer, J.; Wennerberg, K.; Medema, R.; Joensuu, H.; Peuhu, E.; De Visser, K.; Narla, G.; Westermarck, J.
10.1101/2020.08.27.269902 — cancer biology — Posted on 2020-08-31
15 Convergent mutations in tissue-specific regulatory regions reveal novel cancer drivers
Sinnott-Armstrong, N.; Seoane, J. A.; Sallari, R.; Pritchard, J. K.; Curtis, C.; Snyder, M. P.
10.1101/2020.08.21.239954 — cancer biology — Posted on 2020-08-31
17 Genetic diversity analysis of Chinese plum (Prunus salicina L.) based on whole-genome resequencing
Wei, X.; Shen, F.; Zhang, Q.; Liu, N.; Zhang, Y.; Xu, M.; Zhang, Y.; Ma, X.; Liu, W.
10.1101/2020.08.28.271411 — genetics — Posted on 2020-08-31
21 Codon-optimized FAM132b prevents diet-induced obesity by modulating adrenergic response and insulin action
Qi, Z.; Xia, J.; Xue, X.; Liu, W.; Huang, Z.; Zhang, X.; Zou, Y.; Liu, J.; Liu, J.; Li, X.; Cao, L.; Li, L.; Cui, Z.; Ji, B.; Zhang, Q.; Ding, S.; Liu, W.
10.1101/2020.08.31.275503 — molecular biology — Posted on 2020-08-31
24 Differential pathogenesis of Usutu virus isolates in mice
Duggal, N. K.; Kuchinsky, S. C.; Hawks, S. A.; Coutermarsh-Ott, S.; Mossel, E.
10.1101/2020.08.31.275149 — microbiology — Posted on 2020-08-31
25 A nanocompartment containing the peroxidase DypB contributes to defense against oxidative stress in M. tuberculosis
Lien, K. A.; Nichols, R. J.; Cassidy-Amstutz, C.; Dinshaw, K.; Knight, M.; Singh, R.; Eltis, L. D.; Savage, D. F.; Stanley, S.
10.1101/2020.08.31.276014 — microbiology — Posted on 2020-08-31
27 A three-dimensional Air-Liquid Interface Culture Model for the Study of Epstein-Barr virus Infection in the Nasopharynx
Ziegler, P.; Bai, Y.; Tian, Y.; Abrahamsson, S.; Green, A.; Moore, J.; Lee, S. E.; Myerburg, M. M.; Park, H. J.; Tang, K.-W.; Shair, K. H. Y.
10.1101/2020.08.31.272096 — microbiology — Posted on 2020-08-31
30 Human T-bet governs innate and innate-like adaptive IFN-γ immunity against mycobacteria
Yang, R.; Mele, F.; Worley, L.; Langlais, D.; Rosain, J.; Benhsaien, I.; Elarabi, H.; Croft, C. A.; Doisne, J.-M.; Zhang, P.; Weisshaar, M.; Jarrossay, D.; Latorre, D.; Shen, Y.; Han, J.; Gruber, C.; Markle, J.; Ali, F. A.; Rahman, M.; Khan, T.; Seeleuthner, Y.; Kerner, G.; Husquin, L. T.; Maclsaac, J.; Jeljeli, M.; Ailal, F.; Kobor, M.; Oleaga-Quintas, C.; Roynard, M.; Bourgey, M.; Baghdadi, J. E.; Boisson-Dupuis, S.; Puel, A.; Batteux, F.; Rozenberg, F.; Marr, N.; Pan-Hammarstrom, Q.; Bogunovic, D.; Quintana-Murci, L.; Carroll, T.; Ma, C.; Abel, L.; Bousfiha, A.; Di Santo, J.; Glimcher, L. H
10.1101/2020.08.31.274589 — immunology — Posted on 2020-08-31
32 Morphological and biochemical repercussions of Toxoplasma gondii infection in a 3D human brain neurospheres model
Leite, P. E. C.; Portes, J. d. A.; Pereira, M. R.; Russo, F. B.; Martins-Duarte, E. S.; dos Santos, N. A.; Attias, M.; Barrantes, F. J.; Beltrao-Braga, P. C. B.; de Souza, W.
10.1101/2020.08.31.274985 — neuroscience — Posted on 2020-08-31
35 ZNF410 represses fetal globin by devoted control of CHD4/NuRD
Vinjamur, D. S.; Yao, Q.; Cole, M. A.; McGuckin, C.; Ren, C.; Zeng, J.; Hossain, M.; Luk, K.; Wolfe, S. A.; Pinello, L.; Bauer, D. E.
10.1101/2020.08.31.272856 — genetics — Posted on 2020-08-31
36 Pattern regulation in a regenerating jellyfish
Sinigaglia, C.; Peron, S.; Eichelbrenner, J.; Chevalier, S.; Steger, J.; Barreau, C.; Houliston, E.; Leclere, L.
10.1101/2019.12.22.886200 — developmental biology — Posted on 2020-08-31
39 Biological Structure and Function Emerge from Scaling Unsupervised Learning to 250 Million Protein Sequences
Rives, A.; Meier, J.; Sercu, T.; Goyal, S.; Lin, Z.; Guo, D.; Ott, M.; Zitnick, C. L.; Ma, J.; Fergus, R.
10.1101/622803 — synthetic biology — Posted on 2020-08-31
40 Genetic determinants of EGFR-Driven Lung Cancer Growth and Therapeutic Response In Vivo
Foggetti, G.; Li, C.; Cai, H.; Hellyer, J.; Lin, W.-Y.; Ayeni, D.; Hastings, K.; Choi, J.; Wurtz, A.; Andrejka, L.; Maghini, D.; Rashleigh, N.; Levy, S.; Homer, R.; Gettinger, S.; Diehn, M.; Wakelee, H.; Petrov, D.; Winslow, M. M.; Politi, K.
10.1101/2020.04.13.036921 — cancer biology — Posted on 2020-08-31
42 In silico Characterization of Class II Plant Defensins from Arabidopsis thaliana
Costa, L. M.; Pires, A. S.; Damaceno, N. B.; Rigueiras, P. O.; Maximiano, M. R.; Franco, O. L.; Porto, W. F.
10.1101/2020.04.27.065185 — bioinformatics — Posted on 2020-08-31
44 Evidence for the Placenta-Brain Axis: Multi-Omic Kernel Aggregation Predicts Intellectual and Social Impairment in Children Born Extremely Preterm
Santos, H. P.; Bhattacharya, A.; Joseph, R. M.; Smeester, L.; Kuban, K. C.; Marsit, C. J.; O'Shea, T. M.; Fry, R. C.
10.1101/2020.07.19.211029 — genomics — Posted on 2020-08-31
49 Knockdown of the E3 Ubiquitin ligase UBR5 and its role in skeletal muscle anabolism
Turner, D. C.; Hughes, D. C.; Baehr, L. M.; Seaborne, R. A.; Viggars, M.; Jarvis, J. C.; Gorski, P. P.; Stewart, C. E.; Owens, D. J.; Bodine, S. C.; Sharples, A. P.
10.1101/2020.06.05.116145 — cell biology — Posted on 2020-08-31
50 Small RNA modifications in Alzheimers disease
Zhang, X.; Trebak, F.; Souza, L. A. C.; Shi, J.; Zhou, T.; Kehoe, P. G.; Chen, Q.; Feng Earley, Y.
10.1101/2020.04.30.071100 — cell biology — Posted on 2020-08-31
51 Channeling macrophage polarization via selective translation inhibition by rocaglates increases macrophage resistance to Mycobacterium tuberculosis
Chatterjee, S.; Yabaji, S. M.; Bhattacharya, B.; Waligurski, E.; Vallavoju, N.; Ray, S.; Brown, L. E.; Beeler, A. B.; Ivanov, A. R.; Kobzik, L.; Porco, J. A.; Kramnik, I.
10.1101/691808 — immunology — Posted on 2020-08-31
56 Dopaminergic modulation of reward discounting: a systematic review and meta-analysis
Castrellon, J. J.; Meade, J.; Greenwald, L.; Hurst, K.; Samanez-Larkin, G. R.
10.1101/2020.04.03.024364 — neuroscience — Posted on 2020-08-31
57 Low-N protein engineering with data-efficient deep learning
Biswas, S.; Khimulya, G.; Alley, E. C.; Esvelt, K. M.; Church, G. M.
10.1101/2020.01.23.917682 — synthetic biology — Posted on 2020-08-31
65 Strain-dependent modifier genes determine survival in Zfp423 mice
Alcaraz, W. A.; Liu, Z.; Valdes, P.; Chen, E.; Valdovino Gonzalez, A. G.; Wade, S.; Wong, C.; Kim, E.; Chen, H.-H. M.; Ponn, A.; Concepcion, D.; Hamilton, B. A.
10.1101/2020.05.12.091629 — genetics — Posted on 2020-08-31
68 A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses
Tan, T. K.; Rijal, P.; Rahikainen, R.; Keeble, A.; Schimanski, L.; Hussain, S.; Harvey, R.; Hayes, J.; Edwards, J.; McLean, R.; Martini, V.; Pedrera, M.; Thakur, N.; Conceicao, C.; Dietrich, I.; Shelton, H.; Ludi, A. B.; Wilsden, G.; Browning, C.; Zagrajek, A.; Bialy, D.; Bhat, S.; Stevenson-Leggett, P.; Hollinghurst, P.; Tully, M.; Moffat, K.; Chiu, C.; Waters, R.; Gray, A.; Azhar, M.; Mioulet, V.; Newman, J.; Asfor, A. S.; Burman, A.; Crossley, S.; Hammond, J.; Tchilian, E.; Charleston, B.; Bailey, D.; Tuthill, T. J.; Graham, S.; Malinauskas, T.; Huo, J.; Tree, J.; Buttigieg, K.; Owens, R.;
10.1101/2020.08.31.275701 — immunology — Posted on 2020-08-31
69 APOE2 promotes longevity independent of Alzheimer's disease
Shinohara, M.; Kanekiyo, T.; Tachibana, M.; Kurti, A.; Shinohara, M.; Fu, Y.; Zhao, J.; Han, X.; Sullivan, P.; Rebeck, W.; Fryer, J. D.; Heckman, M.; Bu, G.
10.1101/2020.08.31.255141 — neuroscience — Posted on 2020-08-31
74 ACE2 and SARS-CoV-2 Expression in the Normal and COVID-19 Pancreas
Kusmartseva, I.; Wu, W.; Syed, F.; van der Heide, V.; Jorgensen, M.; Joseph, P.; Tang, X.; Candelario-Jalil, E.; Yang, C.; Nick, H.; Harbert, J.; Posgai, A. L.; Lloyd, R.; Cechin, S.; Pugliese, A.; Campbell-Thompson, M.; Vander Heide, R. S.; Evans-Molina, C.; Homann, D.; Atkinson, M. A.
10.1101/2020.08.31.270736 — pathology — Posted on 2020-08-31
75 CRISPR screens in physiologic medium reveal conditionally essential genes in human cells
Rossiter, N. J.; Huggler, K. S.; Adelmann, C. H.; Keys, H. R.; Soens, R. W.; Sabatini, D. M.; Cantor, J. R.
10.1101/2020.08.31.275107 — cancer biology — Posted on 2020-08-31
76 Ebselen derivatives are very potent dual inhibitors of SARS-CoV-2 proteases - PLpro and Mpro in in vitro studies
Zmudzinski, M.; Rut, W.; Olech, K.; Granda, J.; Giurg, M.; Burda-Grabowska, M.; Zhang, L.; Sun, X.; Lv, Z.; Nayak, D.; Kesik-Brodacka, M.; Olsen, S.; Hilgenfeld, R.; Drag, M.
10.1101/2020.08.30.273979 — biochemistry — Posted on 2020-08-31
77 Population Structure Discovery in Meta-Analyzed Microbial Communities and Inflammatory Bowel Disease
Ma, S.; Shungin, D.; Mallick, H.; Schirmer, M.; Nguyen, L. H.; Kolde, R.; Franzosa, E.; Vlamakis, H.; Xavier, R.; Huttenhower, C.
10.1101/2020.08.31.261214 — genomics — Posted on 2020-08-31
78 A Maize Practical Haplotype Graph Leverages Diverse NAM Assemblies
Valdes Franco, J. A.; Gage, J. L.; Johnson, L. C.; Bradbury, P.; Miller, Z. R.; Buckler, E. S.; Romay, M. C.
10.1101/2020.08.31.268425 — genomics — Posted on 2020-08-31
81 SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 are Expressed in the Pancreas but Not in Islet Endocrine Cells
Coate, K. C.; Cha, J.; Shrestha, S.; Wang, W.; Fasolino, M.; Morgan, A.; Dai, C.; Saunders, D. C.; Aramandla, R.; Jenkins, R.; Kapp, M. E.; Stein, R.; Kaestner, K. H.; Vahedi, G.; Brissova, M.; Powers, A. C.
10.1101/2020.08.31.275719 — cell biology — Posted on 2020-08-31
84 Major functional bias for mitochondrial complexes in genome-wide CRISPR screens
Rahman, M.; Billmann, M.; Costanzo, M.; Aregger, M.; Tong, A. H. Y.; Chan, K.; Ward, H. N.; Brown, K. R.; Andrews, B. J.; Boone, C.; Moffat, J.; Myers, C. L.
10.1101/2020.08.31.273730 — systems biology — Posted on 2020-08-31
86 Two distinct phases of chloroplast biogenesis during de-etiolation in Arabidopsis thaliana
Pipitone, R.; Eicke, S.; Pfister, B.; Glauser, G.; Falconet, D.; Uwizeye, C.; Pralon, T.; Zeeman, S.; Kessler, F.; Demarsy, E.
10.1101/2020.08.30.274043 — plant biology — Posted on 2020-08-31
89 Freeform printing of heterotypic tumor models within cell-laden microgel matrices
Molley, T. G.; Jalandhra, G. K.; Nemec, S. R.; Tiffany, A. S.; Harley, B. A. C.; Hung, T.-t.; Kilian, K. A.
10.1101/2020.08.30.274654 — bioengineering — Posted on 2020-08-31
90 On-rate modulation of cadherin interactions by chemical fragments
Senoo, A.; Ito, S.; Nagatoishi, S.; Saito, Y.; Ueno, G.; Yoshida, K.; Tashima, T.; Kudo, S.; Sando, S.; Tsumoto, K.
10.1101/2020.08.30.274647 — biochemistry — Posted on 2020-08-31
95 Low cost conservation: Fishing gear threats to marine species
Cashion, T.; Tai, T. C.; Lam, V. W. Y.; Pauly, D.; Sumaila, U. R.
10.1101/2020.08.30.273532 — ecology — Posted on 2020-08-31
99 A Duplicated ESCRT-III Factor Blocks Enveloped Virus Budding Without Inhibiting Cellular ESCRT Functions
Rheinemann, L.; Downhour, D. M.; Bredbenner, K.; Mercenne, G.; Davenport, K. A.; Schmitt, P. T.; McCullough, J.; Schmitt, A. P.; Simon, S. M.; Sundquist, W. I.; Elde, N. C.
10.1101/2020.08.30.273656 — immunology — Posted on 2020-08-31
100 cFos ensembles in the dentate gyrus rapidly segregate over time and do not form a stable map of space
Lamothe-Molina, P.; Franzelin, A.; Auksutat, L.; Laprell, L.; Ahlbeck, J.; Kneussel, M.; Engel, A.; Morellini, F.; Oertner, T. G.
10.1101/2020.08.29.273391 — neuroscience — Posted on 2020-08-31
101 A Metabolomic Study of Cervical Dystonia
Liu, C.; Scorr, L. M.; Kilic-Berkmen, G.; Cotton, A.; Factor, S. A.; Freeman, A.; Tran, V.; Liu, K.; Uppal, K.; Jones, D.; Jinnah, H. A.; Sun, Y. V.
10.1101/2020.08.30.274126 — neuroscience — Posted on 2020-08-31
102 Learning receptive field properties of complex cells in V1
Lian, Y.; Almasi, A.; Grayden, D. B.; Kameneva, T.; Burkitt, A. N.; Meffin, H.
10.1101/2020.05.18.101873 — neuroscience — Posted on 2020-08-31
104 Theta oscillations shift towards optimal frequency for cognitive control
Senoussi, M.; Verbeke, P.; Desender, K.; De Loof, E.; Talsma, D.; Verguts, T.
10.1101/2020.08.30.273706 — neuroscience — Posted on 2020-08-31
105 The influence of temporal predictability on express visuomotor responses
Contemori, S.; Loeb, G. E.; Corneil, B. D.; Wallis, G.; Carroll, T. J.
10.1101/2020.08.28.269449 — neuroscience — Posted on 2020-08-31
113 Gonadectomy and blood sampling procedures in small size teleost models
Royan, M. R.; Kanda, S.; Kayo, D.; Song, W.; Ge, W.; Weltzien, F.-A.; FONTAINE, R.
10.1101/2020.08.30.271478 — physiology — Posted on 2020-08-31
114 Student-focused development of a next-generation centrifuge force microscope
Tompkins, K. J.; Berscheid, E. T.; Venkatesh, N.; Andrew, A. J.; Beckman, A. P.; Esler, M. A.; Evans, A. C.; Everett, B. A.; Houtti, M.; Koo, H.; Litzau, L. A.; Nelson, A. T.; Peterson, T. M.; Reid, T. A.; Evans, R. L.; Gordon, W. R.
10.1101/2020.08.30.274373 — biophysics — Posted on 2020-08-31
121 Label-free Isolation and Single Cell Biophysical Phenotyping Analysis of Primary Cardiomyocytes using Inertial Microfluidics
Tavassoli, H.; Rorimpandey, P.; Kang, Y. C.; Carnell, M.; Brownlee, C.; Pimanda, J.; Chan, P. P. Y.; Chandrakanthan, V.
10.1101/2020.08.31.243592 — bioengineering — Posted on 2020-08-31
122 Anatomy and transcription dynamics of wheat ribosomal RNA loci revealed by optical mapping and RNA sequencing
Tulpova, Z.; Kovarik, A.; Toegelova, H.; Kapustova, V.; Navratilova, P.; Hribova, E.; Vrana, J.; Macas, J.; Dolezel, J.; Simkova, H.
10.1101/2020.08.29.273623 — genomics — Posted on 2020-08-31
123 De novo genome assembly of the Tobacco Hornworm moth (Manduca sexta)
Gershman, A.; Romer, T. G.; Fan, Y.; Razaghi, R.; Smith, W. A.; Timp, W.
10.1101/2020.08.29.270983 — genomics — Posted on 2020-08-31
124 Haplotype-resolved genome assembly enables gene discovery in the red palm weevil Rhynchophorus ferrugineus
Dias, G. B.; Altammami, M. A.; El-Shafie, H. A. F.; Alhoshani, F. M.; Al-Fageeh, M. B.; Bergman, C. M.; Manee, M. M.
10.1101/2020.08.30.273383 — genomics — Posted on 2020-08-31
132 Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect splicing
Martinez, N. M.; Gilbert, W. V.; Yeo, G. W.; Su, A.; Schaening, C.; Burns, M. C.; Nussbacher, J. K.; Sathe, S.
10.1101/2020.08.29.273565 — molecular biology — Posted on 2020-08-31
133 Loss of mitochondrial protease CLPP activates type I interferon responses through the mtDNA-cGAS-STING signaling axis
Torres-Odio, S.; Lei, Y.; Gispert, S.; Maletzko, A.; Key, J.; Menissy, S.; Wittig, I.; Auburger, G. W. J.; West, A. P.
10.1101/2020.08.30.274712 — immunology — Posted on 2020-08-31
139 CUBIC-Cloud: An Integrative Computational Framework Towards Community-Driven Whole-Mouse-Brain Mapping
Mano, T.; Murata, K.; Kon, K.; Shimizu, C.; Ono, H.; Shi, S.; Yamada, R. G.; Miyamichi, K.; Susaki, E. A.; Touhara, K.; Ueda, H. R.
10.1101/2020.08.28.271031 — neuroscience — Posted on 2020-08-31
140 Zinc potentiates dopamine neurotransmission and cocaine seeking
Gomez, J. L.; Bonaventura, J.; Keighron, J.; Wright, K. M.; Marable, D. L.; Rodriguez, L. A.; Lam, S.; Carlton, M. L.; Ellis, R. J.; Jordan, C.; Bi, G.-H.; Pignatelli, M.; Bannon, M. J.; Xi, Z.-X.; Tanda, G.; Michaelides, M.
10.1101/2020.08.29.273482 — neuroscience — Posted on 2020-08-31
141 Estimating the effect of a scanner upgrade on measures of grey matter structure for longitudinal designs
Medawar, E.; Thieleking, R.; Manuilova, I.; Paerisch, M.; Villringer, A.; Witte, A. V.; Beyer, F.
10.1101/2020.08.28.271296 — neuroscience — Posted on 2020-08-31
142 X-ray mediated scintillation increases synaptic activity via Cerium-doped LSO and Channelrhodopsin-2
Bartley, A. F.; Fischer, M.; Bagley, M. E.; Barnes, J. A.; Burdette, M. K.; Cannon, K. E.; Bolding, M. S.; Foulger, S. H.; McMahon, L. L.; Weick, J. P.; Dobrunz, L. E.
10.1101/2020.08.29.273359 — neuroscience — Posted on 2020-08-31
145 Modeling stem cell nucleus mechanics using confocal microscopy
Kennedy, Z.; Newberg, J. K.; Goelzer, M.; Judex, S.; Fitzpatrick, C. K.; Uzer, G.
10.1101/2020.08.31.274092 — bioengineering — Posted on 2020-08-31
148 Combinatorial Intracellular Delivery Screening (CIDS) of Anticancer Drugs
Sola-Barrado, B.; Moreira-Leite, D.; Scarpa, E.; Duro-Castano, A.; Battaglia, G.
10.1101/2020.08.28.271429 — bioengineering — Posted on 2020-08-31
150 Wing tags severely impair movement in African Cape Vulture
Curk, T.; Scacco, M.; Safi, K.; Wikelski, M.; Fiedler, W.; Kemp, R.; Wolter, K.
10.1101/2020.08.28.271700 — animal behavior and cognition — Posted on 2020-08-31
154 UHRF1 suppresses viral mimicry through both DNA methylation-dependent and -independent mechanisms
Irwin, R. E.; Scullion, C. A.; Thursby, S.-J.; Sun, M. L.; Thakur, A.; Rothbart, S. B.; Xu, G. L.; Walsh, C. P.
10.1101/2020.08.31.274894 — genomics — Posted on 2020-08-31
155 Emergence of Lyme disease on treeless islands in Scotland, UK
Millins, C.; Leo, W.; MacInnes, I.; Ferguson, J.; Charlesworth, G.; Nayar, D.; Davison, R.; Yardley, J.; Kilbride, E.; Huntley, S.; Gilbert, L.; Viana, M.; Johnson, P. C. D.; Biek, R.
10.1101/2020.08.31.263319 — ecology — Posted on 2020-08-31
156 A novel humanized mouse model to study mucosal HIV-1 transmission and prevention
Vanshylla, K.; Held, K.; Eser, T.; Gruell, H.; Jain, K.; Weiland, D.; Muench, J.; Gruettner, B.; Geldmacher, C.; Klein, F.
10.1101/2020.08.31.274167 — immunology — Posted on 2020-08-31
158 Serotonergic Effects on Interoception
Livermore, J. J. A.; Holmes, C. L.; Moga, G.; Adamatzky, K.; Critchley, H.; Garfinkel, S.; Campbell-Meiklejohn, D.
10.1101/2020.08.28.262550 — neuroscience — Posted on 2020-08-31
159 A Population Receptive Field Model of the Magnetoencephalography Response
Kupers, E. R.; Edadan, A.; Benson, N. C.; Zuiderbaan, W.; De Jong, M. C.; Dumoulin, S. O.; Winawer, J.
10.1101/2020.08.28.272534 — neuroscience — Posted on 2020-08-31
160 Reporting to the Convention on Biology Diversity: How are countries assessing and protecting their genetic diversity?
Hoban, S.; Campbell, C.; da Silva, J.; Ekblom, R.; Funk, W. C.; Garner, B.; Godoy, J. A.; Kershaw, F.; MacDonald, A.; Mergeay, J.; Minter, M.; O'Brien, D.; Paz-Vinas, I.; Pearson, S. K.; Perez-Espona, S.; Potter, K.; Russo, I.-R.; Segelbacher, G.; Vernesi, C.; Hunter, M.
10.1101/2020.08.28.254672 — scientific communication and education — Posted on 2020-08-31
162 N-glucosyltransferase GbNGT1 from Ginkgo complement auxin metabolic pathway
Yin, Q.; Zhang, J.; Wang, S.; Chen, J.; Gao, H.; Guo, C.; Ma, L.; Sun, L.; Chen, S.; Liu, A.
10.1101/2020.08.30.249292 — biochemistry — Posted on 2020-08-31
163 Pervasive compartment-specific regulation of gene expression during homeostatic synaptic scaling
Colameo, D.; Soutschek, M.; Rajman, M.; Bicker, S.; von Ziegler, L.; Bohacek, J.; Germain, P.-L.; Dieterich, C.; Schratt, G.
10.1101/2020.08.31.274993 — neuroscience — Posted on 2020-08-31
165 Head-Direction Coding in the Hippocampal Formation of Birds
Ben-Yishay, E.; Krivoruchko, K.; Ron, S.; Ulanovsky, N.; Derdikman, D.; Gutfreund, Y.
10.1101/2020.08.31.274928 — neuroscience — Posted on 2020-08-31
166 Qtlizer: comprehensive QTL annotation of GWAS results
Munz, M.; Wohlers, I.; Simon, E.; Reinberger, T.; Busch, H.; Schaefer, A. S.; Erdmann, J.
10.1101/495903 — bioinformatics — Posted on 2020-08-31
167 Pancreatlas: applying an adaptable framework to map the human pancreas in health and disease
Saunders, D. C.; Messmer, J.; Kusmartseva, I.; Beery, M. L.; Yang, M.; Atkinson, M. A.; Powers, A. C.; Cartailler, J.-P.; Brissova, M.
10.1101/2020.03.27.006320 — cell biology — Posted on 2020-08-31
168 Adaptation supports short-term memory in a visual change detection task
Hu, B.; Garrett, M. E.; Groblewski, P. A.; Ollerenshaw, D. R.; Shang, J.; Roll, K.; Manavi, S.; Koch, C.; Olsen, S. R.; Mihalas, S.
10.1101/2020.03.06.977512 — neuroscience — Posted on 2020-08-31
170 A JAK/STAT-Mediated Inflammatory Signaling Cascade Drives Oncogenesis In AF10-Rearranged AML
Chen, B.; Deshpande, A.; Barbosa, K. O.; Kleppe, M.; Lei, X.; Yeddula, N.; Rosa Campos, A.; Wechsler-Reya, R.; Bagchi, A.; Meshinchi, S.; Eaves, C. J.; Jeremias, I.; Haferlach, T.; Frank, D.; Ronai, Z.; Chanda, S.; Armstrong, S.; Adams, P.; Levine, R.; Deshpande, A.
10.1101/2020.08.31.273631 — cancer biology — Posted on 2020-08-31
171 BAP1 and YY1 regulate expression of death receptors in malignant pleural mesothelioma
Ishii, Y.; Kolluri, K. K.; Pennycuick, A.; Nigro, E.; Alrifai, D.; Borg, E.; Falzon, M.; Shah, K.; Kumar, N.; Janes, S. M.
10.1101/2020.08.31.274951 — cancer biology — Posted on 2020-08-31
172 Estimating the impact of differential adherence on the comparative effectiveness of stool-based colorectal cancer screening using the CRC-AIM microsimulation model
Piscitello, A.; Saoud, L.; Fendrick, A. M.; Borah, B. J.; Hassmiller Lich, K.; Matney, M.; Ozbay, A. B.; Parton, M.; Limburg, P. J.
10.1101/2020.08.30.271858 — cancer biology — Posted on 2020-08-31
174 Epigenetic regulation of differentially expressed genes between various glioma types
Grabowicz, I. E.; Wilczynski, B.; Kaminska, B.; Roura, A.-J.; Wojtas, B.; Dabrowski, M. J.
10.1101/2020.08.29.272013 — cancer biology — Posted on 2020-08-31
176 Imaging transmembrane dynamics of biomolecules at live cell plasma membranes using quenchers in extracellular environment
Hou, W.; Ma, D.; He, X.; Han, W.; Ma, J.; Xu, C.; Xie, R.; Fan, Q.-h.; Ye, F.; Hu, S.; Lu, Y.; Li, M.
10.1101/2020.08.30.266148 — biophysics — Posted on 2020-08-31
177 Micro-topographical guidance of macropinocytic signaling patches
Honda, G.; Saito, N.; Fujimori, T.; Hashimura, H.; Nakamura, M. J.; Nakajima, A.; Sawai, S.
10.1101/2020.08.29.273185 — biophysics — Posted on 2020-08-31
180 Exploring the evolutionary history of kinetic stability in the alpha-lytic protease family
Nixon, C. F.; Lim, S. A.; Sailer, Z. R.; Zheludev, I. N.; Gee, C. L.; Kelch, B. A.; Harms, M. J.; Marqusee, S.
10.1101/2020.08.30.274340 — biophysics — Posted on 2020-08-31
183 Tissue pressure and cell traction compensate to drive robust aggregate spreading
Yousafzai, M. S.; Yadav, V.; Amiri, S.; Staddon, M.; Tabatabai, A. P.; Errami, Y.; Jaspard, G.; Amiri, S.; Banerjee, S.; Murrell, M. P.
10.1101/2020.08.29.273334 — biophysics — Posted on 2020-08-31
184 Distinct effects of different matrix proteoglycans on collagen fibrillogenesis and cell-mediated collagen reorganization
Chen, D.; Smith, L. R.; Khandekar, G.; Patel, P.; Yu, C. K.; Zhang, K.; Chen, C. S.; Han, L.; Wells, R. G.
10.1101/2020.08.30.274001 — cell biology — Posted on 2020-08-31
186 Plant NLR targets P-type ATPase for executing plasma membrane depolarization leading to calcium influx and cell death
Choi, D.; Lee, H.-Y.; Seo, Y.-E.; Lee, J. H.; Lee, S. E.; Oh, S.; Kim, J.; Jung, S.; Kim, H.; Park, H.; Kim, S.; Mang, H.
10.1101/2020.08.30.274688 — plant biology — Posted on 2020-08-31
188 Spontaneous Cell Fusions as a Mechanism of Parasexual Recombination in Tumor Cell Populations
Miroshnychenko, D.; Baratchart, E.; Ferrall-Fairbanks, M.; Vander Velde, R.; Laurie, M. A.; Bui, M.; Tan, A. C.; Altrock, P. M.; Basanta, D.; Marusyk, A.
10.1101/2020.03.09.984419 — cancer biology — Posted on 2020-08-31
190 Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM
Loveland, A. B.; Svidritskiy, E.; Susorov, D.; Lee, S.; Park, A.; Demo, G.; Gao, F.-B.; Korostelev, A. A.
10.1101/2020.08.30.274597 — biochemistry — Posted on 2020-08-31
194 Live imaging and biophysical modeling support a button-based mechanism of somatic homolog pairing in Drosophila
Child, M. B.; Bateman, J. R.; Jahangiri, A.; Reimer, A.; Lammers, N. C.; Sabouni, N.; Villamarin, D.; McKenzie-Smith, G. C.; Johnson, J. E.; Jost, D.; Garcia, H. G.
10.1101/2020.08.30.265108 — developmental biology — Posted on 2020-08-31
195 mRNA translation control by Dhx36 binding to 5' UTR G-quadruplex structures is essential for skeletal muscle stem cell regenerative functions
Chen, X.; Yuan, J.; Xue, G.; Campanario Sanz, S.; Wang, D.; Wang, W.; Mou, X.; Umar, M. I. I.; Isern, J.; Zhao, Y.; He, L.; Li, Y.; Mann, C. J.; Yu, X.; Wang, L.; Perdiguero, E.; Chen, W.; Xue, Y.; Nagamine, Y.; Kwok, C.-K.; Sun, H.; Munoz-Canoves, P.; Wang, H.
10.1101/2020.08.30.274068 — cell biology — Posted on 2020-08-31
196 The Formin Inhibitor, SMIFH2, Inhibits Members of the Myosin Superfamily
Nishimura, Y.; Shi, S.; Zhang, F.; Liu, R.; Takagi, Y.; Bershadsky, A. D.; viasnoff, v.; Sellers, J. R.
10.1101/2020.08.30.274613 — cell biology — Posted on 2020-08-31
197 Identifications of novel avian and mammalian deltaviruses filled the large evolutionally gaps and revealed inter-family transmission of deltaviruses
Iwamoto, M.; Shibata, Y.; Kawasaki, J.; Kojima, S.; Li, Y.-T.; Iwami, S.; Wu, H.-L.; Wada, K.; Tomonaga, K.; Watashi, K.; Horie, M.
10.1101/2020.08.30.274571 — microbiology — Posted on 2020-08-31
198 Deep Learning for Non-Invasive Cortical Potential Imaging
Razorenova, A.; Yavich, N.; Malovichko, M.; Fedorov, M.; Koshev, N.; Dylov, D. V.
10.1101/2020.06.15.151480 — neuroscience — Posted on 2020-08-31
201 gEAR: gene Expression Analysis Resource portal for community-driven, multi-omic data exploration
Orvis, J.; Gottfried, B.; Kancherla, J.; Adkins, R. S.; Song, Y.; Dror, A. A.; Olley, D.; Rose, K.; Chrysostomou, E.; Kelley, M. C.; Milon, B.; Matern, M. S.; Azaiez, H.; Herb, B.; Colantuoni, C.; Carter, R. L.; Ament, S. A.; Kelley, M. W.; White, O.; Bravo, H. C.; Mahurkar, A.; Hertzano, R.
10.1101/2020.08.28.272039 — bioinformatics — Posted on 2020-08-31
203 CyAnno: A semi-automated approach for cell type annotation of mass cytometry datasets
Kaushik, A.; Dunham, D.; He, Z.; Manohar, M.; Desai, M.; Nadeau, K. C.; Andorf, S.
10.1101/2020.08.28.272559 — bioinformatics — Posted on 2020-08-31
207 The genotypic and genetic diversity of enset (Ensete ventricosum) landraces used in traditional medicine is similar to the diversity found in starchy landraces
Nuraga, G. W.; Feyissa, T.; Tesfaye, K.; Biswas, M. K.; Schwarzacher, T.; Borrell, J.; Wilkin, P.; Demissew, S.; Tadele, Z.; Heslop-Harrison, J. S.
10.1101/2020.08.31.274852 — genetics — Posted on 2020-08-31
212 Maturation of telomere 3'-overhangs is linked to the replication stress response
Henninger, E. E.; Jolivet, P.; Fallet, E.; Benmounah, M.; Xu, Z.; Mattarocci, S.; Teixeira, M. T.
10.1101/2020.08.27.269621 — molecular biology — Posted on 2020-08-31
213 ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expression
Lan, X.; Ren, R.; Feng, R.; Ly, L. C.; Lan, Y.; Zhang, Z.; Aboreden, N.; Qin, K.; Horton, J. R.; Grevet, J. D.; Mayuranathan, T.; Abdulmalik, O.; Keller, C. A.; Giardine, B.; Hardison, R. C.; Crossley, M.; Weiss, M. J.; Cheng, X.; Shi, J.; Blobel, G. A.
10.1101/2020.08.31.274324 — molecular biology — Posted on 2020-08-31
214 The Impact of Pf Bacteriophages on the Fitness of Pseudomonas aeruginosa; A Mathematical Modeling Approach
Pourtois, J. D.; Kratochvil, M. J.; Chen, Q.; Haddock, N. L.; Burgener, E. B.; De Leo, G. A.; Bollyky, P. L.
10.1101/2020.08.30.272203 — microbiology — Posted on 2020-08-31
215 Murine intrarectal instillation of purified recombinant C. difficile toxins enables mechanistic studies of pathogenesis
Markham, N. O.; Bloch, S. C.; Shupe, J. A.; Laubacher, E. N.; Washington, M. K.; Coffey, R. J.; Lacy, D. B.
10.1101/2020.08.30.274738 — microbiology — Posted on 2020-08-31
220 Perturbations of the AMI1 IAM-amidohydrolase expression trigger plant stress responses in Arabidopsis thaliana
Perez-Alonso, M. M.; Ortiz-Garcia, P.; Moya-Cuevas, J.; Lehmann, T.; Sanchez-Parra, B.; Björk, R. G.; Karim, S.; Amirjani, M. R.; Aronsson, H.; Wilkinson, M. D.; Pollmann, S.
10.1101/2020.08.31.275206 — plant biology — Posted on 2020-08-31
223 Lattice micropatterning of electron microscopy grids for improved cellular cryo-electron tomography throughput
Engel, L.; Vasquez, C. G.; Montabana, E. A.; Sow, B. M.; Wakiewicz, M. P.; Weis, W. I.; Dunn, A. R.
10.1101/2020.08.30.272237 — bioengineering — Posted on 2020-08-31
224 Aberrant RNA methylation triggers recruitment of an alkylation repair complex
Brickner, J. R.; Tsao, N.; Rodell, R.; Oyeniran, C.; Lukinovic, V.; Bacolla, A.; Zhang, L.; Soll, J. M.; Casanova, A.; Ganguly, A.; He, C.; Tainer, J.; Reynoird, N.; Mosammaparast, N.
10.1101/2020.08.28.271874 — molecular biology — Posted on 2020-08-31
227 Assembly of bacterial cell division protein FtsZ into dynamic biomolecular condensates
Robles-Ramos, M. A.; Zorrilla, S.; Alfonso, C.; Margolin, W.; Rivas, G.; Monterroso, B.
10.1101/2020.08.27.271288 — biochemistry — Posted on 2020-08-31
230 Visual information routes in the posterior dorsal and ventral face network studied with intracranial neurophysiology, and white matter tract endpoints
Babo-Rebelo, M.; Puce, A.; Bullock, D.; Hugueville, L.; Pestilli, F.; Adam, C.; Lehongre, K.; Lambrecq, V.; Dinkelacker, V.; George, N.
10.1101/2020.05.22.102046 — animal behavior and cognition — Posted on 2020-08-31
232 MyoD is a structure organizer for emergent property of 3D genome architecture in muscle cells
Chen, Q.; Chen, F.; Wang, R.; Shi, M.; Chen, A. K.; Ma, Z.; Li, G.; Wang, M.; Li, H.; Zhang, X.; Ma, J.; Zhong, J.; Chen, M.; Zhang, M. Q.; Zhang, Y.; Chen, Y.; Zhu, D.
10.1101/2020.08.29.273375 — genomics — Posted on 2020-08-30
233 Compositional Variability and Mutation Spectra of Monophyletic SARS-CoV-2 Clades
Teng, X.; Li, Q.; Li, Z.; Zhang, Y.; Niu, G.; Xiao, J.; Yu, J.; Zhang, Z.; Song, S.
10.1101/2020.08.26.267781 — microbiology — Posted on 2020-08-30
234 A Micro-engineered Human Colon Intestine-Chip Platform to Study Leaky Barrier
Apostolou, A.; Panchakshari, R.; Banerjee, A.; Manatakis, D. V.; Paraskevopoulou, M. D.; Luc, R.; Abu Ali, G.; Dimitriou, A.; Lucchesi, C.; Kulkarni, G.; Maulana, T. I.; Bleck, B.; Manolakos, E. S.; Hamilton, G. A.; Giallourakis, C.; Karalis, K.
10.1101/2020.08.28.271759 — bioengineering — Posted on 2020-08-30
235 Expansion Revealing: Decrowding Proteins to Unmask Invisible Brain Nanostructures
Sarkar, D.; Kang, J.; Wassie, A. T.; Schroeder, M. E.; Peng, Z.; Tarr, T. B.; Tang, A.-H.; Niederst, E.; Young, J. Z.; Tsai, L.-H.; Blanpied, T. A.; Boyden, E. S.
10.1101/2020.08.29.273540 — bioengineering — Posted on 2020-08-30
236 Deep learning and alignment of spatially-resolved whole transcriptomes of single cells in the mouse brain with Tangram
Biancalani, T.; Scalia, G.; Buffoni, L.; Avasthi, R.; Lu, Z.; Sanger, A.; Tokcan, N.; Vanderburg, C. R.; Segerstolpe, A.; Zhang, M.; Avraham-Davidi, I.; Vickovic, S.; Nitzan, M.; Ma, S.; Buenrostro, J. D.; Brown, N. B.; Fanelli, D.; Zhuang, X.; Macosko, E.; Regev, A.
10.1101/2020.08.29.272831 — genomics — Posted on 2020-08-30
237 Color morphs of the coral, Acropora tenuis, show different responses to environmental stress and different expression profiles of fluorescent-protein genes
Satoh, N.; Kinjo, K.; Shintaku, K.; Ishimori, H.; Yokokura, A.; Hagiwara, K.; Hisata, K.; Kawamitsu, M.; Koizumi, K.; Shinzato, C.; Zayasu, Y.; Kezuka, D.
10.1101/2020.08.28.272823 — evolutionary biology — Posted on 2020-08-30
240 FlyWire: Online community for whole-brain connectomics
Dorkenwald, S.; McKellar, C.; Macrina, T.; Kemnitz, N.; Lee, K.; Lu, R.; Wu, J.; Popovych, S.; Mitchell, E.; Nehoran, B.; Jia, Z.; Bae, J. A.; Mu, S.; Ih, D.; Castro, M.; Ogedengbe, O.; Halageri, A.; Ashwood, Z.; Zung, J.; Brittain, D.; Collman, F.; Schneider-Mizell, C.; Jordan, C.; Silversmith, W.; Baker, C.; Deutsch, D. M.; Encarnacion-Rivera, L.; Kumar, S.; Burke, A.; Gager, J.; Hebditch, J.; Koolman, S.; Moore, M.; Morejohn, S.; Silverman, B.; Willie, K.; Willie, R.; Yu, S.-c.; Murthy, M.; Seung, H. S.
10.1101/2020.08.30.274225 — neuroscience — Posted on 2020-08-30
241 Basal ganglia high-frequency activity is co-modulated with the phase of motor cortical beta and shifted between the subthalamic nucleus and the internal pallidum during sustained motor control
Fischer, P.; Pogosyan, A.; Green, A. L.; Aziz, T. Z.; Hyam, J.; Foltynie, T.; Limousin, P.; Zrinzo, L.; Samuel, M.; Keyoumars, A.; Da Lio, M.; De Cecco, M.; Luchetti, A.; Brown, P.; Tan, H.
10.1101/2020.08.30.273888 — neuroscience — Posted on 2020-08-30
242 Representational Dynamics Preceding Conscious Access
Alilovic, J.; van Moorselaar, D.; Graetz, M.; van Gaal, S.; Slagter, H. A.
10.1101/2020.08.30.274019 — neuroscience — Posted on 2020-08-30
244 Confinement Discerns Swarmers from Planktonic Bacteria
Chen, W.; Mani, N.; Karani, H.; Li, H.; Mani, S.; Tang, J. X.
10.1101/2020.08.30.274316 — biophysics — Posted on 2020-08-30
247 Genetic Diversity Analysis of Chinese Plums Based on Whole-genome Resequencing
Wei, X.; Shen, F.; Zhang, Q.; Liu, N.; Zhang, Y.; Xu, M.; Zhang, Y.; Ma, X.; Liu, W.
10.1101/2020.08.28.271411 — genetics — Posted on 2020-08-30
248 Natural selection and the advantage of recombination
Gerrish, P. J.; Galeota-Sprung, B.; Cordero, F.; Sniegowski, P. D.; Colato, A.; Hengartner, N. W.; Vejalla, V.; Chevalier, J.; Ycart, B.
10.1101/2020.08.28.271486 — evolutionary biology — Posted on 2020-08-30
250 How bank vole-PUUV interactions influence the eco-evolutionary processes driving nephropathia epidemica epidemiology: An experimental and genomic approach.
Madrieres, S.; Tatard, C.; Murri, S.; VULIN, J.; Galan, M.; Piry, S.; Pulido, C.; Loiseau, A.; Artige, E.; Benoit, L.; Lemenager, N.; Lakhdar, L.; Charbonnel, N.; Marianneau, P.; Castel, G.
10.1101/2020.08.28.271841 — evolutionary biology — Posted on 2020-08-30
251 Homeotic Regulation of Olfactory Receptor Choice via NFI-dependent Heterochromatic Silencing and Genomic Compartmentalization
Bashkirova, E.; Monahan, K.; Campbell, C. E.; Osinski, J. M.; Tan, L.; Schieren, I.; Barnea, G.; Xie, S.; Gronostajski, R. M.; Lomvardas, S.
10.1101/2020.08.30.274035 — developmental biology — Posted on 2020-08-30
254 The nucleocytosolic O-fucosyltransferase Spindly affects protein expression and virulence in Toxoplasma gondii
Bandini, G.; Agop-Nersesian, C.; van der Wel, H.; Mandalasi, M.; Kim, H.; West, C. M.; Samuelson, J.
10.1101/2020.08.30.274134 — microbiology — Posted on 2020-08-30
255 Cold Exposure Protects from Neuroinflammation Through Immunologic Reprogramming
Spiljar, M.; Steinbach, K.; Rigo, D.; Suarez-Zamorano, N.; Wagner, I.; Hadadi, N.; Vincenti, I.; Page, N.; Klimek, B.; Rochat, M.-A.; Kreutzfeldt, M.; Chevalier, C.; Stojanovic, O.; Mack, M.; Cansever, D.; Greter, M.; Merkler, D.; Trajkovski, M.
10.1101/2020.08.28.269563 — immunology — Posted on 2020-08-30
265 TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin
Swanson, L. A. B.; Katkar, G. D.; Tam, J.; Pranadinata, R.; Chareddy, Y.; Coates, J. E.; Amandachar, M. S.; Castillo, V.; Olson, J.; Nizet, V.; Kufareva, I.; Das, S.; Ghosh, P.
10.1101/2020.08.29.273516 — immunology — Posted on 2020-08-30
268 Highly sensitive in situ proteomics with cleavable fluorescent tyramide reveals human neuronal heterogeneity
Liao, R.; Mondal, M.; Nazaroff, C. D.; Mastroeni, D.; Coleman, P. D.; LaBaer, J.; Guo, J.
10.1101/539106 — systems biology — Posted on 2020-08-30
269 Structure-function analysis of Arabidopsis TOPLESS reveals fundamental conservation of repression mechanisms across eukaryotes
Leydon, A. R.; Wang, W.; Gala, H. P.; Gilmour, S.; Juarez-Solis, S.; Zemke, J. E.; Zahler, M. L.; Zheng, N.; Nemhauser, J. L.
10.1101/2020.03.04.976134 — plant biology — Posted on 2020-08-30
270 SARS-CoV-2 infects human pluripotent stem cell-derived cardiomyocytes, impairing electrical and mechanical function
Marchiano, S.; Hsiang, T.-Y.; Higashi, T.; Kanna, A.; Reinecke, H.; Yang, X.; Pabon, L.; Sniadecki, N. J.; Bertero, A.; Gale, M.; Murry, C. E.
10.1101/2020.08.30.274464 — pathology — Posted on 2020-08-30
273 Structural classification of neutralizing antibodies against the SARS-CoV-2 spike receptor-binding domain suggests vaccine and therapeutic strategies
Barnes, C. O.; Jette, C. A.; Abernathy, M. E.; Dam, K.-M. A.; Esswein, S. R.; Gristick, H. B.; Malyutin, A. G.; Sharaf, N. G.; Huey-Tubman, K. E.; Lee, Y. E.; Robbiani, D. F.; Nussenzweig, M. C.; West, A. P.; Bjorkman, P. J.
10.1101/2020.08.30.273920 — molecular biology — Posted on 2020-08-30
274 μ-Lat: A Mouse Model to Evaluate Human Immunodeficiency Virus Eradication Strategies
Sperber, H. S.; Togarrati, P. P.; Raymond, K. A.; Bouzidi, M. S.; Gilfanova, R.; Gutierrez, A. G.; Muench, M. O.; Pillai, S. K.
10.1101/2020.02.18.955492 — microbiology — Posted on 2020-08-30
275 The global landscape of SARS-CoV-2 genomes, variants, and haplotypes in 2019nCoVR
Song, S.; Ma, L.; Zou, D.; Tian, D.; Li, C.; Zhu, J.; Chen, M.; Wang, A.; Ma, Y.; Li, M.; Teng, X.; Cui, Y.; Duan, G.; Zhang, M.; Jin, T.; Shi, C.; Du, Z.; Zhang, Y.; Liu, C.; Li, R.; Zeng, J.; Hao, L.; Jiang, S.; Chen, H.; Han, D.; Xiao, J.; Zhang, Z.; Zhao, W.; Xue, Y.; Bao, Y.
10.1101/2020.08.30.273235 — genomics — Posted on 2020-08-30
280 Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote beta cell regeneration
Saunders, D. C.; Aamodt, K. I.; Richardson, T. M.; Hopkirk, A.; Khan, Z.; Aramandla, R.; Poffenberger, G.; Jenkins, R.; Flaherty, D. K.; Prasad, N.; Levy, S.; Powers, A.; Brissova, M.
10.1101/2020.08.28.265728 — cell biology — Posted on 2020-08-30
282 Optimized Vivid-derived Magnets photodimerizers for subcellular optogenetics
Benedetti, L.; Marvin, J. S.; Falahati, H.; Guillen-Samander, A.; Looger, L. L.; De Camilli, P.
10.1101/2020.08.28.272807 — cell biology — Posted on 2020-08-30
285 Molecular and electrophysiological features of spinocerebellar ataxia type seven in induced pluripotent stem cells
Burman, R. J.; Watson, L. M.; Smith, D. C.; Raimondo, J. V.; Ballo, R.; Scholefield, J.; Cowley, S. A.; Wood, M. J.; Kidson, S. H.; Greenberg, L. J.
10.1101/288480 — neuroscience — Posted on 2020-08-30
286 EEG in Motion: Using an Oddball Task to Explore Motor Interference in Active Skateboarding
Robles, D.; Kuziek, J. W. P.; Wlasitz, N. A.; Bartlett, N. T.; Hurd, P. L.; Mathewson, K. E.
10.1101/2020.06.08.136960 — neuroscience — Posted on 2020-08-30
287 Different evolutionary pathways of HIV-1 between fetus and mother perinatal transmission pairs indicate unique immune selection pressure in fetuses
Marichannegowda, M. H.; Mengual, M.; Kumar, A.; Giorgi, E. E.; Tu, J.; Martinez, D.; Li, X.; Feng, L.; Permar, S.; Gao, F.
10.1101/2020.08.28.272930 — microbiology — Posted on 2020-08-30
288 Polygenic risk modeling with latent trait-related genetic components
Aguirre, M.; Tanigawa, Y.; Venkataraman, G.; Tibshirani, R.; Hastie, T.; Rivas, M. A.
10.1101/808675 — genomics — Posted on 2020-08-30
290 Human relevance of blocking the Rac1-TRPC5 pathway as a podocyte-protective strategy for progressive kidney diseases
Zhou, Y.; Kim, C.; Pablo, J. L. B.; Zhang, F.; Jung, J. Y.; Xiao, L.; Bazua, S.; Emani, M.; Hopkins, C.; Weins, A.; Greka, A.
10.1101/2020.08.28.272344 — cell biology — Posted on 2020-08-30
291 Cortical morphology at birth reflects spatio-temporal patterns of gene expression in the fetal human brain
Ball, G.; Seidlitz, J.; O'Muircheartaigh, J.; Dimitrova, R.; Fenchel, D.; Makropoulos, A.; Christiaens, D.; Schuh, A.; Passerat-Palmbach, J.; Hutter, J.; Cordero-Grande, L.; Hughes, E.; Price, A.; Hajnal, J. V.; Rueckert, D.; Robinson, E. C.; Edwards, D.
10.1101/2020.01.28.922849 — neuroscience — Posted on 2020-08-30
293 Chrysin, but not the flavone backbone, decreases anxiety-like behavior in animal tests
Ponciano, L. J.; Costa, B. P.; Feitosa, L. M.; Campos, K. S.; Chaves, S. N.; Cueto-Escobedo, J.; Lima-Maximino, M. G.; Rodriguez-Landa, J. F.; Maximino, C.
10.1101/575514 — pharmacology and toxicology — Posted on 2020-08-30
294 Unique mutational changes in SARS-CoV-2 genome: A case study for the largest state of India
Prasad, P.; Prakash, S.; Sahu, K.; Singh, B.; Shukla, S.; Mishra, H.; Khan, D. N.; Prakash, O.; Bhatt, M.; Barik, S.; Asif, M. H.; Sawant, S. V.; Jain, A.; Bag, S. K.
10.1101/2020.08.24.265827 — bioinformatics — Posted on 2020-08-30
296 Shared heritability of face and brain shape distinct from cognitive traits
Naqvi, S.; Sleyp, Y.; Hoskens, H.; Indencleef, K.; Spence, J. P.; Bruffaerts, R.; Radwan, A.; Eller, R. J.; Richmond, S.; Shriver, M. D.; Shaffer, J. D.; Weinberg, S. M.; Walsh, S.; Thompson, J. C.; Pritchard, J. K.; Sunaert, S.; Peeters, H.; Wysocka, J.; Claes, P.
10.1101/2020.08.29.269258 — genetics — Posted on 2020-08-29
300 The connectome of the adult Drosophila mushroom body: implications for function
Li, F.; Lindsey, J.; Marin, E.; Otto, N.; Dreher, M.; Dempsey, G.; Stark, I.; Bates, A. S.; Pleijzier, M. W.; Schlegel, P.; Nern, A.; Takemura, S.; Yang, T.; Francis, A.; Braun, A.; Parekh, R.; Costa, M.; Scheffer, L.; Aso, Y.; Jefferis, G. S. X. E.; Abbott, L. F.; Litwin-Kumar, A.; Waddell, S.; Rubin, G. M.
10.1101/2020.08.29.273276 — neuroscience — Posted on 2020-08-29
303 Silicon Nitride Inactivates SARS-CoV-2 in vitro
Lehman, C. W.; Flur, R.; Kehn-Hall, K.; McEntire, B. J.; Bal, B. S.; Bock, R. M.
10.1101/2020.08.29.271015 — microbiology — Posted on 2020-08-29
304 An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation
Harmse, m.; Habib, M. M.; Nemska, S.; Nicolo, A.; Gilg, A.; Preising, N.; Sokkar, P.; Carmignani, S.; Raasholm, M.; Weidinger, G.; Kizilsavas, G.; Wagner, M.; Staendker, L.; Abadi, A. M.; Jumaa, H.; Kirchhoff, F.; Frossard, N.; Sanchez-Garcia, E.; Muench, J.
10.1101/2020.08.28.272781 — immunology — Posted on 2020-08-29
306 Snord67 promotes lymph node metastasis and regulates U6-mediated alternative splicing in breast cancer
Chao, Y. L.; Zhu, Y.; Wiedner, H. J.; Tsai, Y.-H.; Wilkinson, L.; Porrello, A.; Van Swearingen, A. E. D.; Carey, L. A.; Giudice, J.; Holley, C. L.; Pecot, C. V.
10.1101/2020.08.28.272617 — cancer biology — Posted on 2020-08-29
309 Future carbon emissions from global mangrove forest loss
Adame, M. F.; Connolly, R. M.; Turschwell, M.; Lovelock, C. E.; Fatoyinbo, T.; Lagomasino, D.; Goldberg, L.; Holdorf, J.; Friess, D.; Sasmito, S. D.; Sanderman, J.; Sievers, M.; Buelow, C.; Kauffman, B. J.; Bryan-Brown, D.; Brown, C. J.
10.1101/2020.08.27.271189 — biochemistry — Posted on 2020-08-29
312 Single Gyroid and Inverse b.c.c. Photonic Crystals in Bird Feathers
SARANATHAN, V.; Narayanan, S.; Sandy, A. R.; Dufresne, E. R.; Prum, R. O.
10.1101/2020.08.27.271213 — evolutionary biology — Posted on 2020-08-29
313 Proximity labeling at non-centrosomal microtubule-organizing centers reveals VAB-10B and WDR-62 as distinct microtubule regulators
Sanchez, A. D.; Branon, T. C.; Cote, L. E.; Papagiannakis, A.; Liang, X.; Shen, K.; Jacobs-Wagner, C.; Ting, A. Y.; Feldman, J. L.
10.1101/2020.08.29.272369 — cell biology — Posted on 2020-08-29
314 Transcription coordinates histone amounts and genome content
Claude, K.-L.; Bureik, D.; Adarska, P.; Singh, A.; Schmoller, K. M.
10.1101/2020.08.28.272492 — molecular biology — Posted on 2020-08-29
316 DNA barcoding analysis of more than 1000 marine yeast isolates reveals previously unrecorded species
PrasannaKumar, C.; Velmurugan, S.; Subramanian, K.; Pugazhvendan, S. R.; Senthil Nagaraj, D.; Feroz Khan, K.; Sadiappan, B.; Manokaran, S.; Hemalatha, K. R.
10.1101/2020.08.29.273490 — microbiology — Posted on 2020-08-29
317 Different evolutionary pathways of HIV-1 between fetus and mother perinatal transmission pairs indicate unique immune selection pressure in fetuses
Gao, F.; Permar, S.; Marichannegowda, M. H.; Mengual, M.; Kumar, A.; Giorgi, E. E.; Tu, J.; Martinez, D.; Li, X.; Feng, L.
10.1101/2020.08.28.272930 — microbiology — Posted on 2020-08-29
318 Hyaluronan Synthesis Inhibition Impairs Antigen Presentation and Delays Transplantation Rejection
Marshall, P. L.; Nagy, N.; Kaber, G.; Barlow, G. L.; Ramesh, A.; Xie, B. J.; Linde, M. H.; Haddock, N. L.; Lester, C. A.; Tran, Q.-L.; de Vries, C. R.; Malkovskiy, A.; Gurevich, I.; Martinez, H.; Kuipers, H. F.; Yadava, K.; Zhang, X.; Evanko, S. P.; Gebe, J. A.; Wang, X.; Vernon, R. B.; Hargil, A.; de la Motte, C.; Wight, T. N.; Engleman, E. G.; Krams, S. M.; Meyer, E.; Bollyky, P. L.
10.1101/2020.08.28.272443 — immunology — Posted on 2020-08-29
321 Neural vulnerability and hurricane-related media predict posttraumatic stress in youth
Dick, A. S.; Silva, K.; Gonzalez, R.; Sutherland, M. T.; Laird, A. R.; Thompson, W. K.; Tapert, S. F.; Squeglia, L. M.; Gray, K. M.; Nixon, S. J.; Cottler, L. B.; La Greca, A. M.; Gurwitch, R. H.; Comer, J. S.
10.1101/2020.08.27.271056 — neuroscience — Posted on 2020-08-29
323 Global BioID-based SARS-CoV-2 proteins proximal interactome unveils novel ties between viral polypeptides and host factors involved in multiple COVID19-associated mechanisms
Laurent, E. M.; Sofianatos, Y.; Komarova, A.; Gimeno, J.-P.; Samavarchi Tehrani, P.; Kim, D.-K.; Abdouni, H.; Duhamel, M.; Cassonnet, P.; Knapp, J. J.; Kuang, D.; Chawla, A.; Sheykhkarimli, D.; Rayhan, A.; Li, R.; Pogoutse, O.; Hill, D. E.; Calderwood, M. E.; Falter-Braun, P.; Aloy, P.; Stelzl, U.; Vidal, M.; Gingras, A.-C.; Pavlopoulos, G. A.; Van Der Werf, S.; Fournier, I.; Roth, F. P.; Salzet, M.; Demeret, C.; Jacob, Y.; Coyaud, E.
10.1101/2020.08.28.272955 — systems biology — Posted on 2020-08-29
325 Genetics of phosphorus use efficiency in a MAGIC wheat population grown in the field
Wasson, A. P.; Zwart, A. B.; Verbyla, A. P.; Permalloo, G.; Weligama, C.; Ryan, P. R.; Delhaize, E.
10.1101/2020.08.27.271205 — plant biology — Posted on 2020-08-29
332 Divergent DNA methylation signatures underlying X chromosome regulation in marsupials and eutherians
Singh, D.; Sun, D.; King, A. G.; Alquezar-Planas, D. E.; Johnson, R. N.; Alvarez-Ponce, D.; Yi, S. V.
10.1101/2020.08.26.269068 — evolutionary biology — Posted on 2020-08-29
334 Transcriptomic response during wasp parasitism in the Drosophila-Spiroplasma interaction
Higareda Alvear, V. M.; Mateos, M.; Cortez Quezada, D.; Tamborindeguy, C.; Martinez Romero, E.
10.1101/2020.08.27.270462 — ecology — Posted on 2020-08-29
335 Genomic Diversity of Escherichia coli isolates from healthy children in rural Gambia
Foster-Nyarko, E.; Alikhan, N.-F.; Ikumapayi, U. N.; Golam, S.; Hossain, M. J.; Okoi, C.; Tientcheu, P.-E.; Defernez, M.; OGrady, J.; Antonio, M.; Pallen, M. J.
10.1101/2020.08.28.271627 — ecology — Posted on 2020-08-29
336 Single-cell analysis of human trophoblast stem cell specification reveals activation of fetal cytotrophoblast expression programs including coronavirus associated host factors and human endogenous retroviruses
Tietze, E.; Barbosa, A. R.; Euclydes, V.; Cho, H. J.; Lee, Y. K.; Feltrin, A.; Leemput, J. v. d.; Carlo, P. D.; Sawada, T.; Benjamin, K. J.; Brentani, H.; Kleinman, J. E.; Hyde, T. M.; Weinberger, D. A.; Ursini, G.; McKay, R.; Paquola, A. C. M.; Shin, J. H.; Erwin, J. A.
10.1101/2020.08.29.273425 — developmental biology — Posted on 2020-08-29
338 Human relevance of blocking the Rac1-TRPC5 pathway as a podocyte-protective strategy for progressive kidney diseases
Zhou, Y.; Kim, C.; Pablo, J. L. B.; Zhang, F.; Jung, J. Y.; Xiao, L.; Bazua, S.; Emani, M.; Weins, A.; Greka, A.
10.1101/2020.08.28.272344 — cell biology — Posted on 2020-08-29
339 The SARS-CoV-2 ORF10 is not essential in vitro or in vivo in humans.
Pancer, K.; Milewska, A.; Owczarek, K.; Dabrowska, A.; Branicki, W.; Sanak, M.; Pyrc, K.
10.1101/2020.08.29.257360 — microbiology — Posted on 2020-08-29
340 A simplified cell-based assay to identify coronavirus 3CL protease inhibitors
Resnick, S. J.; Iketani, S.; Hong, S. J.; Zask, A.; Liu, H.; Kim, S.; Melore, S.; Nair, M. S.; Huang, Y.; Tay, N. E. S.; Rovis, T.; Yang, H. W.; Stockwell, B. R.; Ho, D. D.; Chavez, A.
10.1101/2020.08.29.272864 — microbiology — Posted on 2020-08-29
342 Coformulation with tattoo ink for immunological assessment of vaccine immunogenicity in the draining lymph node
Barber-Axthelm, I. M.; Kelly, H. G.; Esterbauer, R.; Wragg, K.; Gibbon, A.; Lee, W. S.; Wheatley, A. K.; Kent, S. J.; Tan, H.-X.; Juno, J. A.
10.1101/2020.08.27.270975 — immunology — Posted on 2020-08-29
343 Genetic Underpinnings of Risky Behaviour Relate to Altered Neuroanatomy
Aydogan, G.; Daviet, R.; Karlsson Linner, R.; Hare, T. A.; Kable, J. W.; Kranzler, H. R.; Wetherill, R. R.; Ruff, C. C.; Koellinger, P. D.; Nave, G.
10.1101/862417 — neuroscience — Posted on 2020-08-29
346 The Mechanism of MICU-Dependent Gating of theMitochondrial Ca2+ Uniporter
Garg, V.; Paranjpe, I.; Unsulangi, T.; Suzuki, J.; Milescu, L. S.; Kirichok, Y.
10.1101/2020.04.04.025833 — biophysics — Posted on 2020-08-29
347 A Fast and Accessible Method for the Isolation of RNA, DNA, and Protein to Facilitate the Detection of SARS-CoV-2
Ponce-Rojas, J. C.; Costello, M. S.; Proctor, D. A.; Kosik, K. S.; Wilson, M. Z.; Arias, C.; Acosta-Alvear, D.
10.1101/2020.06.29.178384 — molecular biology — Posted on 2020-08-29
350 A negative feedback model to explain regulation of SARS-CoV-2 replication and transcription
Shan, G.; Zhi, C.; Xiufeng, J.; Fang, W.; Yibo, X.; Hao, Z.; Chang, L.; Jishou, R.; Guangyou, D.; Xin, L.
10.1101/2020.08.23.263327 — bioinformatics — Posted on 2020-08-29
351 Phylogenetic Analysis Of SARS-CoV-2 In The First Months Since Its Emergence
Pereson, M. J.; Mojsiejczuk, L.; Martinez, A. P.; Flichman, D. M.; Garcia, G. H.; Di Lello, F. A.
10.1101/2020.07.21.212860 — evolutionary biology — Posted on 2020-08-29
352 A Scalable, Easy-to-Deploy, Protocol for Cas13-Based Detection of SARS-CoV-2 Genetic Material
Rauch, J. N.; Valois, E.; Solley, S. C.; Braig, F.; Audouard, M.; Lach, R. S.; Ponce-Rojas, J. C.; Costello, M. S.; Baxter, N. J.; Kosik, K. S.; Arias, C.; Acosta-Alvear, D.; Wilson, M. Z.
10.1101/2020.04.20.052159 — molecular biology — Posted on 2020-08-29
353 Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators
Gomes Dias, S. S.; Cardoso, V. S.; Ferreira, A. C.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Temerozo, J. R.; Teixeira, L.; Barreto, E. A.; Mattos, M.; de Freitas, C. S.; Azevedo-Quintanilha, I.; Manso, P. P. A.; Hottz, E. D.; Pao, C. R. R.; Bou-Habib, D. C.; Bozza, F. A.; Souza, T. M. L.; Bozza, P. T.
10.1101/2020.08.22.262733 — immunology — Posted on 2020-08-29
360 A dual mechanism of enhancer activation by FOXA pioneer factors induces endodermal organ fates
Geusz, R. J.; Wang, A.; Lam, D. K.; Vinckier, N. K.; Alysandratos, K.-D.; Roberts, D. A.; Wang, J.; Kefalopoulou, S.; Qiu, Y.; Chiou, J.; Gaulton, K. J.; Ren, B.; Kotton, D. N.; Sander, M.
10.1101/2020.08.28.263020 — genomics — Posted on 2020-08-29
364 LPA and APOE are associated with statin selection in the UK Biobank
Lavertu, A.; McInnes, G. M.; Tanigawa, Y.; Altman, R. B.; Rivas, M. A.
10.1101/2020.08.28.272765 — genetics — Posted on 2020-08-29
368 A neurite-zippering mechanism, mediated by layer-specific expression of IgCAMs, regulates synaptic laminar specificity in the C. elegans nerve ring neuropil
Sengupta, T.; Koonce, N. L.; Moyle, M. W.; Duncan, L. H.; Vazquez-Martinez, N.; Han, X.; Shao, L.; Wu, Y.; Santella, A.; Fan, L.; Bao, Z.; Mohler, W. A.; Shroff, H.; Colon-Ramos, D.
10.1101/2020.08.28.271437 — neuroscience — Posted on 2020-08-29
369 SynapsEM: computer-assisted synapse morphometry
Watanabe, S.; Davis, M. W.; Kusick, G. F.; Iwasa, J.; Jorgensen, E. M.
10.1101/2020.08.28.271882 — neuroscience — Posted on 2020-08-29
372 miRNA-mediated loss of m6A increases nascent translation in glioblastoma
Zepecki, J. P.; Karambizi, D.; Fajardo, J. E.; Snyder, K. M.; Guetta-Terrier, C.; Tang, O. Y.; Chen, J.-S.; Sarkar, A.; Fiser, A.; Toms, S. A.; Tapinos, N.
10.1101/2020.08.28.271536 — cancer biology — Posted on 2020-08-29
373 Peptide-based Inhibitors of Protein-Protein Interactions of Src Homology 2 Domain-Containing Phosphatase 2
Bobone, S.; Pannone, L.; Biondi, B.; Solman, M.; Flex, E.; Canale, V.; Calligari, P.; De Faveri, C.; Gandini, T.; Quercioli, A.; Torini, G.; Venditti, M.; Lauri, A.; Fasano, G.; Hoeksma, J.; Santucci, V.; Cattani, G.; Bocedi, A.; Carpentieri, G.; Tirelli, V.; Sanchez, M.; Peggion, C.; Formaggio, F.; Den Hertog, J.; Martinelli, S.; Bocchinfuso, G.; Tartaglia, M.; Stella, L.
10.1101/2020.08.28.271809 — biophysics — Posted on 2020-08-28
374 The Bgee suite: integrated curated expression atlas and comparative transcriptomics in animals
Bastian, F. B.; Roux, J.; Niknejad, A.; Comte, A.; Fonseca Costa, S. S.; Mendes de Farias, T.; Moretti, S.; Parmentier, G.; Rech de Laval, V.; Rosikiewicz, M.; Wollbrett, J.; Echchiki, A.; Gharib, W. H.; Gonzales-Porta, M.; Jarosz, Y.; Laurenczy, B.; Moret, P.; Person, E.; Roelli, P.; Sanjeev, K.; Seppey, M.; Robinson-Rechavi, M.
10.1101/2020.05.28.119560 — bioinformatics — Posted on 2020-08-28
375 PopDel identifies medium-size deletions jointly in tens of thousands of genomes
Niehus, S.; Jonsson, H.; Schönberger, J.; Björnsson, E.; Beyter, D.; Eggertsson, H. P.; Sulem, P.; Stefansson, K.; Halldorsson, B. V.; Kehr, B.
10.1101/740225 — bioinformatics — Posted on 2020-08-29
377 The genetic and physical interactomes of the Saccharomyces cerevisiae Hrq1 helicase
Rogers, C. M.; Sanders, E.; Nguyen, P. A.; Smith-Kinnaman, W.; Mosley, A. L.; Bochman, M. L.
10.1101/2020.08.28.272674 — genetics — Posted on 2020-08-28
379 Kinesin-4 KIF21B limits microtubule growth to allow rapid centrosome polarization in T cells.
Hooikaas, P. J.; Damstra, H. G. J.; Gros, O. J.; van Riel, W. E.; Martin, M.; Smits, Y. T. H.; van Loosdregt, J.; Kapitein, L. C.; Berger, F.; Akhmanova, A.
10.1101/2020.08.28.271643 — cell biology — Posted on 2020-08-28
385 Optimization and scaling of patient-derived brain organoids uncovers deep phenotypes of disease
Shah, K.; Bedi, R.; Rogozhnikov, A.; Ramkumar, P.; Tong, Z.; Rash, B.; Stanton, M.; Sorokin, J.; Apaydin, C.; Batarse, A.; Bergamaschi, J.; Blattner, R.; Brown, S.; Bosshardt, A.; Castrillo, C.; Dang, B.; Drusinsky, S.; Enriquez, L.; Grayson, D.; Hilliard, J.; Hsu, P.-K.; Johnson, C.; Jones, R.; Lash, A.; Lee, C.-Y.; Li, K.; McKay, A.; Mount, E.; Nicola, J.; Oumzil, I.; Paek, J.; Pascoe, D.; Piepho, A.; Poust, S.; Quang, D.; Schultz, M.; Sims, J.; Taylor, P.; Treiman, G.; Wueseke, O.; Young, N.; Pollen, A. A.; Flanzer, D.; Chao, D.; Skibinski, G.; Kato, S.; Escola, S.
10.1101/2020.08.26.251611 — neuroscience — Posted on 2020-08-29
388 Ontogeny and Vulnerabilities of Lapatinib Drug-Tolerant Persisters in HER2+ Breast Cancer
Neel, B. G.; Chang, C. A.; Jiang, S.; Sayad, A.; Brown, K. R.; Nixon, A.; Dhabaria, A.; Tang, K. H.; Moffat, J.; Ueberheide, B.; Khodadadi-Jamayran, A.; Tsirigos, A.
10.1101/2020.08.28.273029 — cancer biology — Posted on 2020-08-28
389 Gene expression has more power for predicting in vitro cancer cell vulnerabilities than genomics
Dempster, J. M.; Krill-Burger, J.; Warren, A.; McFarland, J.; Boehm, J. S.; Vazquez, F.; Hahn, W.; Golub, T.; Tsherniak, A.
10.1101/2020.02.21.959627 — cancer biology — Posted on 2020-08-28
392 A Single-cell RNA-seq Training and Analysis Suite using the Galaxy Framework
Tekman, M.; Batut, B.; Ostrovsky, A.; Antoniewski, C.; Clements, D.; Ramirez, F.; Etherington, G. J.; Hotz, H.-R.; Scholtalbers, J.; Manning, J. R.; Bellenger, L.; Doyle, M. A.; Heydarian, M.; Huang, N.; Soranzo, N.; Moreno, P.; Mautner, S.; Papatheodorou, I.; Nekrutenko, A.; Taylor, J.; Blankenberg, D.; Backofen, R.; Grüning, B.
10.1101/2020.06.06.137570 — bioinformatics — Posted on 2020-08-28
396 Structure of bacterial phospholipid transporter MlaFEDB with substrate bound
Coudray, N.; Isom, G. L.; MacRae, M. R.; Saiduddin, M. N.; Bhabha, G.; Ekiert, D. C.
10.1101/2020.06.02.129247 — biochemistry — Posted on 2020-08-28
405 Size-independent mRNA synthesis and chromatin-based partitioning mechanisms generate and maintain constant amounts of protein per cell
Swaffer, M. P.; Chandler-Brown, D.; Langhinrichs, M.; Marinov, G.; Greenleaf, W.; Kundaje, A.; Schmoller, K. M.; Skotheim, J. M.
10.1101/2020.08.28.272690 — cell biology — Posted on 2020-08-28
407 Genome-wide analysis of in vivo CcpA binding with and without its key co-factor HPr in the major human pathogen group A Streptococcus.
DebRoy, S.; Tobar, V. A.; Galvez, G.; Arora, S.; Liang, X.; Horstmann, N. M.; Maracaja-Coutinho, V.; Latorre, M.; Hook, M.; Flores, A. R.; Shelburne, S.
10.1101/2020.08.28.272682 — microbiology — Posted on 2020-08-28
408 The Gut Microbiome of Exudivorous Wild and Captive Marmosets
Malukiewicz, J.; Cartwright, R. A.; Dergam, J. A.; Igayara, C. S.; Kessler, S.; Moreira, S. B.; Nash, L. T.; Nicola, P. A.; Pereira, L. C. M.; Pissinati, A.; Ruiz-Miranda, C. R.; Ozga, A. T.; Roos, C.; Silva, D. L.; Stone, A. C.; Grativol, A. D.
10.1101/708255 — microbiology — Posted on 2020-08-28
410 Population Genomics of Plasmodium vivax in Panama to Assess the Risk of Case Importation on Malaria Elimination
Buyon, L. E.; Santamaria, A. M.; Early, A. M.; Quijada, M.; Barahona de Mosca, I.; Lasso, J.; Avila, M.; Volkman, S. K.; Marti, M.; Neafsey, D. E.; Obaldia, N.
10.1101/2020.08.26.267823 — microbiology — Posted on 2020-08-28
411 Anoxygenic phototrophic Chloroflexota member uses a Type I reaction center
Tsuji, J. M.; Shaw, N. A.; Nagashima, S.; Venkiteswaran, J. J.; Schiff, S. L.; Hanada, S.; Tank, M.; Neufeld, J. D.
10.1101/2020.07.07.190934 — microbiology — Posted on 2020-08-28
412 HIV-specific T-cell responses reflect substantive in vivo interactions with infected cells despite long-term therapy
Stevenson, E.; Ward, A.; Truong, R.; Thomas, A.; Huang, S. H.; Dilling, T.; Terry, S.; Bui, J.; Mota, T.; Danesh, A.; Lee, G.; Gramatica, A.; Khadka, P.; Alberto, W. C.; Gandhi, R.; McMahon, D.; Lalama, C.; Bosch, R.; Macatangay, B.; Cyktor, J.; Eron, J.; Mellors, J.; Jones, R. B.
10.1101/2020.08.28.272625 — immunology — Posted on 2020-08-28
414 Regulation of Decay Accelerating Factor primes human germinal center B cells for phagocytosis
Dernstedt, A.; Leidig, J.; Holm, A.; Mjosberg, J.; Ahlm, C.; Henriksson, J.; Huldtin, m.; Forsell, M. N.
10.1101/2020.08.27.271148 — immunology — Posted on 2020-08-28
416 Hericerin derivatives from Hericium erinaceus exert BDNF-like neurotrophic activity in central hippocampal neurons and enhance memory
Martinez-Marmol, R.; Chai, Y.; Khan, Z.; Kim, S. B.; Hong, S. M.; Gormal, R.; Lee, D.; Lee, J. K.; Lee, M. K.; Kim, S. Y.; Meunier, F. A.
10.1101/2020.08.28.271676 — neuroscience — Posted on 2020-08-28
420 Cortical thickness estimation in individuals with cerebral small vessel disease, focal atrophy, and chronic stroke lesions.
Ozzoude, M.; Ramirez, J.; Raamana, P. R.; Holmes, M. F.; Walker, K.; Scott, C. J. M.; Goubran, M.; Kwan, D.; Tartaglia, M. C.; Beaton, D.; Saposnik, G.; Hassan, A.; Lawrence-Dewar, J.; Dowlatshahi, D.; Strother, S. C.; Symons, S.; Bartha, R.; Swartz, R. H.; Black, S. E.; on behalf of the ONDRI Investigators,
10.1101/2020.08.04.236760 — neuroscience — Posted on 2020-08-28
425 Effects of early life stress on bone homeostasis in mice and humans
Wuertz-Kozak, K.; Roszkowski, M.; Cambria, E.; Block, A.; Kuhn, G. A.; Abele, T.; Hitzl, W.; Driesslein, D.; Mueller, R.; Rapp, M.; Mansuy, I. M.; Peters, E. M. J.; Wippert, P. M.
10.1101/2020.07.21.214122 — physiology — Posted on 2020-08-28
426 Neoplastic and Immune single cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma.
Riemondy, K. A.; Venkataraman, S.; Willard, N.; Nellan, A.; Sanford, B.; Griesinger, A. M.; Amani, V.; Mitra, S.; Hankinson, T. C.; Handler, M. H.; Sill, M.; Ocasio, J.; Weir, S. J.; Malawsky, D. S.; Gershon, T. R.; Garancher, A.; Wechsler-Reya, R. J.; Hesselberth, J. R.; Foreman, N. K.; Donson, A. M.; Vibhakar, R.
10.1101/2020.08.28.272021 — cancer biology — Posted on 2020-08-28
427 Selective Labeling and Identification of the Tumor Cell Proteome of Pancreatic Cancer In Vivo
Azizian, N. G.; Sullivan, D. K.; Nie, L.; Pardo, S.; Molleur, D.; Chen, J.; Weintraub, S. T.; Li, Y.
10.1101/2020.05.25.113670 — cancer biology — Posted on 2020-08-28
428 FRETboard: semi-supervised classification of FRET traces
de Lannoy, C. V.; Filius, M.; Kim, S. H.; Joo, C.; de Ridder, D.
10.1101/2020.08.28.272195 — biophysics — Posted on 2020-08-28
429 A Bitopic Miniprotein Regulates a Membrane-Embedded Enzyme via Topological Allostery
Weber, D. K.; Hernandez, M. S.; Reddy, V. U.; Wang, S.; Larsen, E. K.; Tata, G.; Gustavsson, M.; Cornea, R. L.; Thomas, D. D.; De Simone, A.; Veglia, G.
10.1101/2020.08.28.271940 — biophysics — Posted on 2020-08-28
430 Capturing non-local through-bond effects when fragmenting molecules for quantum chemical torsion scans
Stern, C. D.; Bayly, C. I.; Smith, D. G. A.; Fass, J.; Wang, L.-P.; Mobley, D. L.; Chodera, J. D.
10.1101/2020.08.27.270934 — biophysics — Posted on 2020-08-28
431 Multi-modal Nonlinear Optical and Thermal Imaging Platform for Label-Free Characterization of Biological Tissue
Adams, W. R.; Mehl, B.; Lieser, E.; Wang, M.; Patton, S.; Throckmorton, G. A.; Jenkins, J. L.; Ford, J. B.; Gautam, R.; Brooker, J.; Jansen, E. D.; Mahadevan-Jansen, A.
10.1101/2020.04.06.023820 — biophysics — Posted on 2020-08-28
433 Long-read sequencing resolves structural variants in SERPINC1 causing antithrombin deficiency and identifies a complex rearrangement and a retrotransposon insertion not characterized by routine diagnostic methods
de la Morena-Barrio, B.; Stephens, J.; de la Morena-Barrio, M. E.; Stefanucci, L.; Padilla, J.; Miñano, A.; Gleadall, N.; Luis García, J.; López-Fernández, M. F.; Morange, P.-E.; Puurunen, M. K.; Undas, A.; Vidal, F.; NIHR BioResource, ; Raymond, F. L.; Vicente García, V.; Ouwehand, W. H.; Corral, J.; Sanchis-Juan, A.
10.1101/2020.08.28.271932 — genomics — Posted on 2020-08-28
434 Genome-wide transcript and protein analysis reveals distinct features of aging in the mouse heart
Gerdes Gyuricza, I.; Chick, J. M.; Keele, G. R.; Deighan, A. G.; Munger, S. C.; Korstanje, R. C.; Gygi, S. P.; Churchill, G. A.
10.1101/2020.08.28.272260 — genomics — Posted on 2020-08-28
438 Sequence analysis of Indian SARS-CoV-2 isolates shows a stronger interaction of mutated receptor binding domain with ACE2 receptor
Dash, P.; Turuk, J.; Behera, S. K.; Palo, S. K.; Raghav, S.; Ghosh, A.; Sabat, J.; Rath, S.; Subhadra, S.; Bhattacharya, D.; Kanungo, S.; Kshatri, J.; Mishra, B. k.; Dash, S.; Mahapatra, N.; Parida, A.; Pati, S.
10.1101/2020.08.28.271601 — microbiology — Posted on 2020-08-28
439 An integrative approach points to membrane composition as a key factor in E. coli persistence
Canas-Duarte, S. J.; Perez-Lopez, M. I.; Herrfurth, C.; Sun, L.; Contreras, L. M.; Feussner, I.; Leidy, C.; Riano-Pachon, D. M.; Restrepo, S.; Pedraza, J. M.
10.1101/2020.08.28.271171 — microbiology — Posted on 2020-08-28
441 Microbiota Accelerates Age-Related CpG island Methylation in Colonic Mucosa
Sun, A.; Cole, L.; Maegawa, S.; Park, P. H.; Keith, K.; Madzo, J.; Jelinek, J.; Jobin, C.; Issa, J.-P. J.
10.1101/2020.08.28.268367 — microbiology — Posted on 2020-08-28
442 The high-affinity immunoglobulin receptor FcγRI potentiates HIV-1 neutralization via antibodies against the gp41 N-heptad repeat
Montefiori, D. C.; Filsinger Interrante, M. V.; Bell, B. N.; Rubio, A. A.; Joyce, J. G.; Shiver, J. W.; LaBranche, C. C.; Kim, P. S.
10.1101/2020.08.27.271064 — immunology — Posted on 2020-08-28
444 Synaptic vesicle fusion along axons is driven by myelination and subsequently accelerates sheath growth in an activity-regulated manner
Almeida, R. G.; Williamson, J. M.; Madden, M. E.; Early, J. J.; Voas, M. G.; Talbot, W. S.; Bianco, I. H.; Lyons, D. A.
10.1101/2020.08.28.271593 — neuroscience — Posted on 2020-08-28
446 Resolvin D1 and D2 reduce SARS-Cov-2-induced inflammation in cystic fibrosis macrophages
Recchiuti, A.; Patruno, S.; Mattoscio, D.; Isopi, E.; Pomilio, A.; Lamolinara, A.; Iezzi, M.; Pecce, R.; Romano, M.
10.1101/2020.08.28.255463 — pathology — Posted on 2020-08-28
447 A subset of pediatric thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR
Sievers, P.; Sill, M.; Schrimpf, D.; Stichel, D.; Reuss, D. E.; Sturm, D.; Hench, J.; Frank, S.; Krskova, L.; Vicha, A.; Zapotocky, M.; Bison, B.; Harter, P. N.; Snuderl, M.; Kramm, C. M.; Reifenberger, G.; Korshunov, A.; Jabado, N.; Wesseling, P.; Wick, W.; Solomon, D. A.; Perry, A.; Jacques, T. S.; Jones, C.; Witt, O.; Pfister, S. M.; von Deimling, A.; Jones, D. T. W.; Sahm, F.
10.1101/2020.08.28.239160 — cancer biology — Posted on 2020-08-28
451 De Novo Mutation in an Enhancer of EBF3 in simplex autism
Padhi, E. M.; Hayeck, T. J.; Mannion, B.; Chatterjee, S.; Byrska-Bishop, M.; Musunuri, R.; Narzisi, G.; Abhyankar, A.; Cheng, Z.; Hunter, R. D.; Akiyama, J.; Fries, L. E.; Ng, J.; Stong, N.; Allen, A. S.; Dickel, D. E.; Bernier, R. A.; Gorkin, D. U.; Pennacchio, L. A.; Zody, M. C.; Turner, T. N.
10.1101/2020.08.28.270751 — genomics — Posted on 2020-08-28
452 Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2
Ghahremanpour, M. M.; Tirado-Rives, J.; Deshmukh, M.; Ippolito, J. A.; Zhang, C.-H.; Cabeza de Vaca, I.; Liosi, M.-E.; Anderson, K. S.; Jorgensen, W. L.
10.1101/2020.08.28.271957 — pharmacology and toxicology — Posted on 2020-08-28
453 The Pharmacodynamic-Toxicodynamic Relationship of AUC and CMAX in Vancomycin Induced Kidney Injury in an Animal Model
Avedissian, S.; Pais, G.; Liu, J.; O'Donnell, J. N.; Lodise, T.; Neely, M.; Prozialeck, W.; Lamar, P.; Becher, L.; Scheetz, M. H.
10.1101/2020.08.27.270793 — pharmacology and toxicology — Posted on 2020-08-28
459 Transcriptomic response during wasp parasitism in the Drosophila-Spiroplasma interaction
Higareda Alvear, V. M.; Mateos, M.; Cortez Quezada, D.; Martinez Romero, E.; Tamborindeguy, C.
10.1101/2020.08.27.270462 — ecology — Posted on 2020-08-28
461 Investigation of anti-IgLON5-induced neurodegenerative changes in human neurons
Gamre, M.; Ryding, M.; Nissen, M. S.; Nilsson, A. C.; Meyer, M.; Blaabjerg, M.
10.1101/2020.08.27.269795 — neuroscience — Posted on 2020-08-28
462 Bundle-specific associations between white matter microstructure and Aβ and tau pathology at their connecting cortical endpoints in older adults at risk of Alzheimer's disease
Pichet Binette, A.; Theaud, G.; Rheault, F.; Roy, M.; Collins, D. L.; Breitner, J. C. S.; Poirier, J.; Descoteaux, M.; Villeneuve, S.; PREVENT-AD Research Group,
10.1101/2020.08.27.266551 — neuroscience — Posted on 2020-08-28
466 Measuring Orthopedic Plate Strain to Track Bone Healing Using a Fluidic Sensor Read via Plain Radiography
Rajamanthrilage, A.; Arifuzzaman, M.; Millhouse, P. W.; Pace, T. B.; Behrend, C. J.; DesJardins, J. D.; Anker, J. N.
10.1101/2020.08.27.268169 — bioengineering — Posted on 2020-08-28
467 Three-dimensional residual channel attention networks denoise and sharpen fluorescence microscopy image volumes
Chen, J.; Sasaki, H.; Lai, H.; Su, Y.; Liu, J.; Wu, Y.; Zhovmer, A.; Combs, C. A.; Rey-Suarez, I.; Chang, H.; Huang, C. C.; Li, X.; Guo, M.; Nizambad, S.; Upadhyaya, A.; Lucas, L. A. G.; Lee, S.-J. J.; Shroff, H.
10.1101/2020.08.27.270439 — bioengineering — Posted on 2020-08-28
468 An 8 Dipole Transceive and 24 Loop Receive Array for Non-Human Primate Head Imaging at 10.5T
Lagore, R. L.; Moeller, S.; Zimmermann, J.; DelaBarre, L.; Radder, J.; Grant, A.; Ugurbil, K.; Yacoub, E.; Harel, N.; Adriany, G.
10.1101/2020.08.27.270744 — bioengineering — Posted on 2020-08-28
469 Base Pairing and Functional Insights into N3-methylcytidine (m3C) in RNA
Mao, S.; Haruehanroengra, P.; Ranganathan, S. V.; Shen, F.; Begley, T.; Sheng, J.
10.1101/2020.08.27.270322 — biochemistry — Posted on 2020-08-28
470 Analysis of Inositol Phosphate Metabolism by Capillary Electrophoresis Electrospray Ionization Mass Spectrometry (CE-ESI-MS)
Qiu, D.; Wilson, M. S.; Eisenbeis, V. B.; Harmel, R.; Riemer, E.; Haas, T. M.; Wittwer, C.; Jork, N.; Gu, C.; Shears, S. B.; Schaaf, G.; Kammerer, B.; Fiedler, D.; Saiardi, A.; Jessen, H. J.
10.1101/2020.08.27.270405 — biochemistry — Posted on 2020-08-28
471 Genome-wide analysis of cis-regulatory changes in the metabolic adaptation of cavefish
Krishnan, J.; Seidel, C.; Zhang, N.; VanCampen, J.; Peuss, R.; Xiong, S.; Kenzior, A.; Li, H.; Conaway, J. W.; Rohner, N.
10.1101/2020.08.27.270371 — genomics — Posted on 2020-08-28
472 Compensation for the absence of the catalytically active half of DNA polymerase ε in yeast by positively selected mutations in CDC28 gene
Stepchenkova, E. I.; Zhuk, A. S.; Cui, J.; Tarakhovskaya, E. R.; Barbari, S. R.; Shcherbakova, P. V.; Polev, D. E.; Fedorov, R.; Poliakov, E.; Rogozin, I. B.; Lada, A. G.; Pavlov, Y. I.
10.1101/2020.08.27.269241 — genetics — Posted on 2020-08-28
475 New insights on species divergence in red panda
Joshi, B. D.; Dalui, S.; Singh, S. K.; Mukherjee, T.; Chandra, K.; Sharma, L. K.; Thakur, M.
10.1101/2020.08.27.268607 — evolutionary biology — Posted on 2020-08-28
479 Comparative study of a 3CLpro inhibitor and remdesivir against both major SARS-CoV-2 clades in human airway models
de Vries, M.; Mohamed, A.; Prescott, R. A.; Valero-Jimenez, A.; Desvignes, L.; O'Connor, R.; Steppan, C.; Anderson, A.; Binder, J.; Dittmann, M.
10.1101/2020.08.28.272880 — microbiology — Posted on 2020-08-28
481 Plasmablast-derived antibody response to acute SARS-CoV-2 infection in humans
Huang, K.-Y. A.; Tan, T.; Chen, T.-H.; Huang, C.-G.; Harvey, R.; Hussain, S.; Chen, C.-P.; Harding, A.; Gilbert-Jaramillo, J.; Liu, X.; Knight, M.; Schimanski, L.; Shih, S.-R.; Lin, Y.-C.; Cheng, C.-Y.; Cheng, S.-H.; Huang, Y.-C.; Lin, T.-Y.; Rahikainen, R.; Howarth, M.; Jan, J.-T.; Ma, C.; James, W. S.; Daniels, R.; McCauley, J.; Rijal, P.; Townsend, A.
10.1101/2020.08.28.267526 — microbiology — Posted on 2020-08-28
483 A single immunization with spike-functionalized ferritin vaccines elicits neutralizing antibody responses against SARS-CoV-2 in mice
Powell, A. E.; Zhang, K.; Sanyal, M.; Tang, S.; Weidenbacher, P. A.; Li, S.; Pham, T. D.; Pak, J. E.; Chiu, W.; Kim, P. S.
10.1101/2020.08.28.272518 — immunology — Posted on 2020-08-28
484 Birth weight is associated with brain tissue volumes seven decades later, but not with age-associated changes to brain structure
Wheater, E. N.; Shenkin, S. D.; Munoz Maniega, S.; Valdes Hernandez, M.; Wardlaw, J.; Deary, I.; Bastin, M. E.; Boardman, J. P.; Cox, S. R.
10.1101/2020.08.27.270033 — neuroscience — Posted on 2020-08-28
485 Laser Ablation of the Pia Mater for Insertion of High-Density Microelectrode Arrays in a Translational Sheep Model
Boergens, K. M.; Tadic, A.; Hopper, M. S.; Sahasrabuddhe, K.; Kong, Y.; Straka, M.; Sohal, H. H. S.; Angle, M. R.
10.1101/2020.08.27.269233 — neuroscience — Posted on 2020-08-28
487 Predicting the Health Impact of Dietary Polyphenols Using a Network Medicine Framework
do Valle, I. F.; Roweth, H. G.; Malloy, M. W.; Moco, S.; Barron, D.; Battinelli, E.; Loscalzo, J.; Barabasi, A.-L.
10.1101/2020.08.27.270173 — bioinformatics — Posted on 2020-08-28
491 Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics
Akinci, E.; Cha, M.; Lin, L.; Yeo, G.; Hamilton, M. C.; Donahue, C. J.; Bermudez-Cabrera, H. C.; Zanetti, L. C.; Chen, M.; Barkal, S. A.; Khowpinitchai, B.; Chu, N.; Velimirovic, M.; Jodhani, R.; Fife, J. D.; Sovrovic, M.; Cole, P. A.; Davey, R. A.; Cassa, C. A.; Sherwood, R. I.
10.1101/2020.08.27.270819 — genetics — Posted on 2020-08-28
493 A SARS-CoV-2 BioID-based virus-host membrane protein interactome and virus peptide compendium: new proteomics resources for COVID-19 research
St-Germain, J. R.; Astori, A.; Samavarchi-Tehrani, P.; Abdouni, H.; Macwan, V.; Kim, D.-K.; Knapp, J. J.; Roth, F. P.; Gingras, A.-C.; Raught, B.
10.1101/2020.08.28.269175 — cell biology — Posted on 2020-08-28
494 SARS-CoV-2 spike D614G variant exhibits highly efficient replication and transmission in hamsters
Mok, B. W. Y.; Cremin, C. J.; Lau, S.-Y.; Deng, S.; Chen, P.; Zhang, A. J.; Lee, A. C.-Y.; Liu, H.; Liu, S.; Ng, T. T.-L.; Lao, H.-Y.; Lee, E. L.-K.; Leung, K. S.-S.; Wang, P.; To, K. K.-W.; Chan, J. F.-W.; Chan, K.-H.; Yuen, K.-Y.; Siu, G. K.-H.; Chen, H.
10.1101/2020.08.28.271635 — microbiology — Posted on 2020-08-28
495 Immune response to vaccine candidates based on different types of nanoscaffolded RBD domain of the SARS-CoV-2 spike protein
Lainscek, D.; Fink, T.; Forstneric, V.; Hafner-Bratkovic, I.; Orehek, S.; Strmsek, Z.; Mancek Keber, M.; Pecan, P.; Esih, H.; Malensek, S.; Aupic, J.; Dekleva, P.; Plaper, T.; Vidmar, S.; Kadunc, L.; Bencina, M.; Pojer, F.; Lau, K.; Hacker, D.; Correia, B.; Peterhoff, D.; Wagner, R.; Jerala, R.
10.1101/2020.08.28.244269 — immunology — Posted on 2020-08-28
496 Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip 1
Lee, M.; Betz, C.; Paatero, I.; Schellinx, N. C.; Yin, J.; Wilson, C. W.; Ye, W.; Affolter, M.; Belting, H.-G.
10.1101/2020.08.27.269977 — developmental biology — Posted on 2020-08-28
497 PIEZO ion channel is required for root mechanotransduction in Arabidopsis thaliana
Patapoutian, A.; Mousavi, S. A. R.; Dubin, A. E.; Zeng, W.-Z.; Coombs, A. M.; Do, K.; Ghadiri, D. A.; Zhao, Y.; Ge, C.
10.1101/2020.08.27.270355 — plant biology — Posted on 2020-08-28
500 Lipoprotein particles interact with membranes and transfer their cargo without receptors
Plochberger, B.; Sych, T.; Weber, F.; Novacek, J.; Axmann, M.; Stangl, H.; Sezgin, E.
10.1101/2020.08.27.270496 — biophysics — Posted on 2020-08-28
502 MCART1 is required for mitochondrial NAD transport
Kory, N.; uit de Bos, J.; van der Rijt, S.; Jankovic, N.; Guera, M.; Arp, N.; Pena, I. A.; Prakash, G.; Chan, S. H.; Kunchok, T.; Lewis, C. A.; Sabatini, D. M.
10.1101/2020.08.28.267252 — cell biology — Posted on 2020-08-28
504 Role of channels in the oxygen permeability of red blood cells
Zhao, P.; Geyer, R. R.; Salameh, A. I.; Wass, A. B.; Taki, S.; Huffmann, D. E.; Meyerson, H. J.; Occhipinti, R.; Moss, F. J.; Boron, W. F.
10.1101/2020.08.28.265066 — physiology — Posted on 2020-08-28
505 BNIP3 phosphorylation by JNK1/2 promotes mitophagy via enhancing its stability under hypoxia
He, Y.-L.; Gong, S.-H.; Cheng, X.; Zhao, M.; Zhao, T.; Zhao, Y.; Fan, M.; Zhu, L.-L.; Wu, L.-Y.
10.1101/2020.08.27.271270 — cell biology — Posted on 2020-08-28
508 The ascorbate-deficient guinea pig model of shigellosis allows the study of the entire Shigella life cycle
Andre, A. C.; Mulet, C.; Anderson, M. C.; Injarabian, L.; Buck, A.; Prade, V. M.; Walch, A.-K.; Lykkesfeldt, J.; Sansonetti, P. J.; Marteyn, B. S.
10.1101/2020.08.28.270074 — microbiology — Posted on 2020-08-28
509 First isolation and genetic characterization of Puumala orthohantavirus strains from France
Vulin, J.; Murri, S.; Madrieres, S.; Galan, M.; Tatard, C.; Piry, S.; Vaccari, G.; D'agostino, C.; Charbonnel, N.; Castel, G.; Marianneau, P.
10.1101/2020.08.27.270181 — microbiology — Posted on 2020-08-28
511 Phosphate Induces a Morphological Shift that Enhances Vascular Dissemination of Cryptococcus neoformans
Denham, S. T.; Brammer, B.; Chung, K. Y.; Wambaugh, M. A.; Bednarek, J.; Guo, L.; Brown, J. C. S.
10.1101/2020.08.27.270843 — microbiology — Posted on 2020-08-28
512 Functional correlation of H3K9me2 and nuclear compartment formation
Fukuda, K.; Shimura, C.; Miura, H.; Tanigawa, A.; Suzuki, T.; Dohmae, N.; Hiratani, I.; Shinkai, Y.
10.1101/2020.08.28.271221 — molecular biology — Posted on 2020-08-28
513 Structural analysis of the Legionella pneumophila Dot/Icm Type IV Secretion System Core Complex
Durie, C. L.; Sheedlo, M. J.; Chung, J. M.; Byrne, B.; Su, M.; Knight, T.; Swanson, M.; Lacy, B.; Ohi, M. D.
10.1101/2020.08.28.271460 — microbiology — Posted on 2020-08-28
514 Projection of gut microbiome pre and post-bariatric surgery to predict surgery outcome
Ben Izhak, M.; Eshel, A.; cohen, r.; Madar-Shapiro, L.; meiri, h.; Wachtel, C.; Leung, C.; Messick, E.; Jongkam, N.; mavor, E.; Sapozhnikov, S.; Maharashak, N.; Abu-Abeid, S.; alis, A.; Mahler, I.; meoded, a.; Meron Eldar, S.; Koren, O.; Louzoun, Y.
10.1101/2020.08.27.271312 — microbiology — Posted on 2020-08-28
517 Abnormal morphology biases haematocrit distribution in tumour vasculature and contributes to heterogeneity in tissue oxygenation
Bernabeu, M. O.; Kory, J.; Grogan, J. A.; Markelc, B.; Beardo, A.; d'Avezac, M.; Enjalbert, R.; Kaeppler, J.; Daly, N.; Hetherington, J.; Krueger, T.; Maini, P. K.; Pitt-Francis, J. M.; Muschel, R. J.; Alarcon, T.; Byrne, H. M.
10.1101/640060 — cancer biology — Posted on 2020-08-28
524 Cryo-EM structure of the MgtE Mg2+ channel pore domain in Mg2+-free conditions reveals cytoplasmic pore opening
Jin, F.; Sun, M.; Fujii, T.; Yamada, Y.; Wang, J.; Maturana, A.; Wada, M.; Su, S.; Ma, J.; Takeda, H.; Kusakizako, T.; Tomita, A.; Nakura, Y. N.; Liu, K.; Uemura, T.; Nomura, Y.; Nomura, N.; Ito, K.; Nureki, O.; Namba, K.; Iwata, S.; Yu, Y.; Hattori, M.
10.1101/2020.08.27.270991 — biophysics — Posted on 2020-08-28
526 Evidence of hidden hunger in Darwin's finches as a result of non-native species invasion of the Galapagos cloud forest
Hood-Nowotny, R.; Rabitsch, I.; Cimadom, A.; Suarez-Rubio, M.; Watzinger, A.; Schmidt Yanez, P.; Schulze, C.; Zechmeister-Boltenstern, S.; Jäger, H.; Tebbich, S.
10.1101/2020.08.26.268136 — ecology — Posted on 2020-08-28
527 Optimized DNA isolation method for microbiome analysis of human tissues
Bruggeling, C. E.; Garza, D. R.; Achouiti, S.; Mes, W.; Dutilh, B. E.; Boleij, A.
10.1101/2020.08.25.267641 — microbiology — Posted on 2020-08-28
530 Prostate Epithelial Genes Define Docetaxel-Sensitive Prostate Cancer Molecular Subtype
Han, H.; Choi, K.; Moon, Y. J.; Heo, J. E.; Ham, W. S.; Jang, W. S.; Rha, K. H.; Cho, N. H.; Giancotti, F. G.; Choi, Y. D.
10.1101/2020.08.26.269415 — cancer biology — Posted on 2020-08-28
531 A targetable epigenetic vulnerability in PI3K/AKT inhibitor resistant cancers
Huang, H.; Wu, D.; Yan, Y.; Wei, T.; Ye, Z.; Xiao, Y.; Pan, Y.; Orme, J. J.; Wang, D.; Wang, L.; Ren, S.
10.1101/2020.08.27.269613 — cancer biology — Posted on 2020-08-28
535 Serratia marcescens secretes proteases and chitinases with larvicidal activity against Anopheles dirus
Jupatanakul, N.; Pengon, J.; Selisana, S. M. G.; Choksawangkarn, W.; Jaito, N.; Saeung, A.; Bunyong, R.; Posayapisit, N.; Thammatinna, K.; Kalpongnukul, N.; Aupalee, K.; Pisitkun, T.; Kamchonwongpaisan, S.
10.1101/2020.05.31.123539 — microbiology — Posted on 2020-08-27
537 Light-powered reactivation of flagella: towards building an artificial cell
Ahmad, R.; Kleineberg, C.; Nasirimarekani, V.; Su, Y. J.; Goli Pozveh, S.; Bae, A. J.; Bodenschatz, E.; Sundmacher, K.; Guido, I.; Vidakovich-Koch, T.; Gholami, A.
10.1101/2020.07.20.212191 — biophysics — Posted on 2020-08-27
539 Epidemiology of Dengue viral infection in Nepal: 2006-2019
Rijal, K. R.; Adhikari, B.; Ghimire, B.; Dhungel, B.; Pyakurel, U. R.; Shah, P.; Bastola, A.; Banjara, M. R.; Pandey, B. D.; Parker, D. M.; Ghimire, P.
10.1101/2020.08.27.269720 — microbiology — Posted on 2020-08-27
541 Phylogenetic population structure and drug resistance of Mycobacterium tuberculosis complex in the Volta Region of Ghana
Ameke, S.; Asare, P.; Aboagye, S. Y.; Otchere, I. D.; Osei-Wusu, S.; Yeboah-Manu, D.; Aasante-Poku, A.
10.1101/2020.08.27.269662 — microbiology — Posted on 2020-08-27
542 SARS-CoV-2 lineage B.6 is the major contributor to transmission in Malaysia
Chong, Y. M.; Sam, I.-C.; Chong, J.; Kahar Bador, M.; Ponnampalavanar, S.; Syed Omar, S. F.; Kamarulzaman, A.; Munusamy, V.; Wong, C. K.; Jamaluddin, F. H.; Chan, Y. F.
10.1101/2020.08.27.269738 — microbiology — Posted on 2020-08-27
543 Experimental pieces of evidence for Mycobacterium ulcerans dormancy.
Drancourt, M.; Loukil, A.; Lalaoui, R.; Bogreau, H.; Regoui, S.; HAMMOUDI, N.
10.1101/2020.08.27.269712 — microbiology — Posted on 2020-08-27
545 Proteomic and transcriptomic profiling reveal different aspects of aging in the kidney
Takemon, Y.; Chick, J. M.; Gyuricza, I. G.; Skelly, D. M.; Devuyst, O.; Gygi, S.; Churchill, G. A.; Korstanje, R.
10.1101/2020.08.27.270504 — systems biology — Posted on 2020-08-27
547 Rapamycin as a potent and selective inhibitor of vascular endothelial growth factor receptor in breast carcinoma
Wan Abdul rahman, W. F.; Muhammad Sakri, M. S.; Tengku Din, T. A. D. A.-A.; Jaafar, H.; Gopalan, V.
10.1101/2020.08.27.269688 — pathology — Posted on 2020-08-27
549 An in vitro Chondro-osteo-vascular Triphasic Model of the Osteochondral Complex
Pirosa, A.; Gottardi, R.; Alexander, P. G.; Puppi, D.; Chiellini, F.; Tuan, R. S.
10.1101/2020.08.27.270660 — bioengineering — Posted on 2020-08-27
553 Reduced Gene Dosage of Histone H4 Prevents CENP-A Mislocalization in Saccharomyces cerevisiae
Eisenstatt, J. R.; Ohkuni, K.; Au, W.-C.; Preston, O.; Suva, E.; Costanzo, M.; Boone, C.; Basrai, M. A.
10.1101/2020.05.29.124032 — genetics — Posted on 2020-08-27
554 Systematic Detection of Large-Scale Multi-Gene Horizontal Transfer in Prokaryotes
Kloub, L.; Gosselin, S. P.; Fullmer, M.; Graf, J.; Gogarten, J. P.; Bansal, M. S.
10.1101/2020.08.27.270926 — evolutionary biology — Posted on 2020-08-27
557 Disproportionate presence of adenosine in mitochondrial and chloroplast DNA of Chlamydomonas reinhardtii
El-Sayed, W. M. M.; Gombolay, A. L.; Xu, P.; Yang, T.; Jeon, Y.; Balachander, S.; Newnam, G.; Tao, S.; Bowen, N. E.; Schinazi, R. F.; Kim, B.; Chen, Y.; Storici, F.
10.1101/2020.08.27.270314 — molecular biology — Posted on 2020-08-27
560 The lncRNA APOLO interacts with the transcription factor WRKY42 to trigger root hair cell expansion in response to cold
Moison, M.; Martinez Pacheco, J.; Lucero, L.; Fonouni-Farde, C.; Rodriguez-Melo, J.; Christ, A.; Bazin, J.; Benhamed, M.; Ibanez, F.; Crespi, M.; Estevez, J.; Ariel, F.
10.1101/2020.07.13.188763 — plant biology — Posted on 2020-08-27
561 Post-EMT: Cadherin-11 mediates cancer hijacking fibroblasts
Kang, W.; Fan, Y.; Du, Y.; Tonkova, E. A.; Hsu, Y.-H.; Tan, K. V.; Alexander, S.; Wong, B. S.; Yang, H.; Luo, J.; Yao, K.; Yang, J.; Hu, X.; Liu, T.; Gan, Y.; Zhang, J.; Zhao, J. J.; Konstantopoulos, K.; Friedl, P.; Khong, P. L.; Lu, A.; Hung, M.-C.; Brenner, M. B.; Segall, J. E.; Gu, Z.
10.1101/729491 — cancer biology — Posted on 2020-08-27
562 On the discovery of population-specific state transitions from multi-sample multi-condition single-cell RNA sequencing data
Crowell, H. L.; Soneson, C.; Germain, P.-L.; Calini, D.; Collin, L.; Raposo, C.; Malhotra, D.; Robinson, M.
10.1101/713412 — bioinformatics — Posted on 2020-08-27
566 Spatially-mapped single-cell chromatin accessibility
Thornton, C. A.; Mulqueen, R. M.; Nishida, A.; Torkenczy, K. A.; Lowenstein, E. G.; Fields, A. J.; Steemers, F. J.; Zhang, W.; McConnell, H. L.; Woltjer, R. L.; Mishra, A.; Wright, K. M.; Adey, A. C.
10.1101/815720 — genetics — Posted on 2020-08-27
568 Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primates
Shearn, R.; Wright, A.; Mousset, S.; Regis, C.; Penel, S.; Lemaitre, J. F.; Douay, G.; Crouau-Roy, B.; Lecompte, E.; Marais, G.
10.1101/445072 — evolutionary biology — Posted on 2020-08-27
571 Compositional Variability and Mutation Spectra of Monophyletic SARS-CoV-2 Clades
Teng, X.; Li, Q.; Li, Z.; Zhang, Y.; Niu, G.; Zhang, M.; Xiao, J.; Yu, J.; Zhang, Z.; Song, S.
10.1101/2020.08.26.267781 — microbiology — Posted on 2020-08-27
574 A rendezvous of two second messengers: The c-di-AMP receptor protein DarB controls (p)ppGpp synthesis in Bacillus subtilis
Krueger, L.; Herzberg, C.; Wicke, D.; Baehre, H.; Heidemann, J. L.; Dickmanns, A.; Schmitt, K.; Ficner, R.; Stuelke, J.
10.1101/2020.08.27.268672 — microbiology — Posted on 2020-08-27
577 The planning horizon for movement sequences
Ariani, G.; Kordjazi, N.; Pruszynski, J. A.; Diedrichsen, J.
10.1101/2020.07.15.204529 — neuroscience — Posted on 2020-08-27
578 In vivo RyR1 reduction in muscle triggers a core-like myopathy
Pelletier, L.; Petiot, A.; Brocard, J.; Giannesini, B.; Giovannini, D.; Sanchez, C.; Travard, L.; Chivet, M.; Beaufils, M.; Kutchukian, C.; Bendahan, D.; Metzger, D.; Franzini Armstrong, C.; Romero, N. B.; Rendu, J.; Jacquemond, V.; Faure, j.; Marty, I.
10.1101/2020.08.27.269647 — neuroscience — Posted on 2020-08-27
579 Optimization and scaling of patient-derived brain organoids uncovers deep phenotypes of disease
Shah, K.; Bedi, R.; Rogozhnikov, A.; Ramkumar, P.; Tong, Z.; Rash, B.; Stanton, M.; Sorokin, J.; Apaydin, C.; Batarse, A.; Bergamaschi, J.; Blattner, R.; Brown, S.; Bosshardt, A.; Castrillo, C.; Dang, B.; Drusinsky, S.; Enriquez, L.; Grayson, D.; Hilliard, J.; Hsu, P.-K.; Johnson, C.; Jones, R.; Lash, A.; Lee, E.; Li, K.; McKay, A.; Mount, E.; Nicola, J.; Oumzil, I.; Paek, J.; Pascoe, D.; Piepho, A.; Poust, S.; Quang, D.; Schultz, M.; Sims, J.; Taylor, P.; Treiman, G.; Wueseke, O.; Young, N.; Pollen, A. A.; Flanzer, D.; Chao, D.; Skibinski, G.; Kato, S.; Escola, S.
10.1101/2020.08.26.251611 — neuroscience — Posted on 2020-08-27
583 Regulation of Vacuole Morphology by PIEZO Channels in Spreading Earth Moss
Radin, I.; Richardson, R. A.; Weiner, E. R.; Bascom, C. S.; Bezanilla, M.; Haswell, E.
10.1101/2020.08.27.269282 — plant biology — Posted on 2020-08-27
584 Epithelial layer unjamming shifts energy metabolism toward glycolysis
DeCamp, S. J.; Tsuda, V. M. K.; Ferruzzi, J.; Koehler, S. A.; Roblyer, D.; Giblin, J. T.; Zaman, M. H.; Weiss, S. T.; DeMarzio, M.; Park, C. Y.; Ogassavara, N. C.; Mitchel, J. A.; Butler, J. P.; Fredberg, J. J.
10.1101/2020.06.30.180000 — biophysics — Posted on 2020-08-27
587 Hydroxylation of antitubercular drug candidate, SQ109, by mycobacterial cytochrome P450
Bukhdruker, S.; Varaksa, T.; Grabovec, I.; Marin, E.; Shabunya, P.; Kadukova, M.; Grudinin, S.; Kavaleuski, A.; Gusach, A.; Gilep, A.; Borshchevskiy, V.; Strushkevich, N.
10.1101/2020.08.27.269936 — biochemistry — Posted on 2020-08-27
588 CRISPR/Cas9-mediated gene editing induces neurological recovery in an A53T-SNCA overexpression rat model of Parkinson's disease
Yoon, H. H.; Ye, S.; Lim, S.; Lee, S. E.; Oh, S.-J.; Jo, A.; Lee, H.; Kim, N.-R.; Kim, K.; Kim, B.-J.; Lee, C. J.; Nam, M.-H.; Hur, J. W.; Jeon, S. R.
10.1101/2020.08.27.269522 — genetics — Posted on 2020-08-27
590 Stromal Heterogeneity in the Proliferative Endometrial Functionalis - A single-cell approach
Queckboerner, S.; von Grothusen, C.; Boggavarapu, N. R.; Davies, L. C.; Gemzell-Danielsson, K.
10.1101/2020.07.17.203844 — molecular biology — Posted on 2020-08-27
593 Common Marmoset Gut Microbiome Profiles in Health and Intestinal Disease
Sheh, A.; Artim, S. C.; Burns, M. A.; Molina-Mora, J. A.; Lee, M. A.; Dzink-Fox, J.; Muthupalani, S.; Fox, J. G.
10.1101/2020.08.27.268524 — microbiology — Posted on 2020-08-27
594 Prospective representations in rat orbitofrontal ensembles
Zhou, J.; Zong, W.; Jia, C.; Gardner, M. P. H.; Schoenbaum, G.
10.1101/2020.08.27.268391 — neuroscience — Posted on 2020-08-27
595 Assessing the cognitive status of Drosophila by the value-based feeding decision
Kao, C.-F.; Yu, C.-C.; Chang, F.-C.; Hong, Y.-H.; Li, J.-C.; Chen, P.-L.; Chen, C.-H.; Chiu, T.-W.; Lu, T.-T.; Wang, Y.-M.
10.1101/2020.08.27.267955 — neuroscience — Posted on 2020-08-27
597 Swirling Instability of the Microtubule Cytoskeleton
Stein, D. B.; De Canio, G.; Lauga, E.; Shelley, M. J.; Goldstein, R. E.
10.1101/2020.08.27.268318 — biophysics — Posted on 2020-08-27
598 Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome
Lago, S.; Cernilogar, F. M.; Kazerani, M.; Dominiguez Moreno, H.; Nadai, M.; Schotta, G.; Richter, S. N.
10.1101/2020.08.27.236778 — genomics — Posted on 2020-08-27
600 Priority effects dictate community structure and alter virulence of fungal-bacterial biofilms
Cheong, J. A.; Johnson, C.; Wan, H.; Lui, A.; Kernien, J.; Gibson, A.; Nett, J.; Kalan, L. R.
10.1101/2020.08.27.267492 — microbiology — Posted on 2020-08-27
601 The cognitive effects of a promised bonus do not depend on dopamine synthesis capacity
Hofmans, L.; van den Bosch, R.; Määttä, J.; Verkes, R.-J.; Aarts, E.; Cools, R.
10.1101/2020.08.26.264168 — neuroscience — Posted on 2020-08-27
603 SARS-CoV-2 Nucleocapsid protein is decorated with multiple N- and O-glycans.
Supekar, N. T.; Shajahan, A.; Gleinich, A.; Rouhani, D.; Heiss, C.; Azadi, P.
10.1101/2020.08.26.269043 — biochemistry — Posted on 2020-08-27
604 Susceptibility of rabbits to SARS-CoV-2
Mykytyn, A. Z.; Lamers, M. M.; Okba, N. M. A.; Breugem, T. I.; Schipper, D.; van den Doel, P. B.; van Run, P.; van Amerongen, G.; de Waal, L.; Koopmans, M.; Stittelaar, K. J.; van den Brand, J.; Haagmans, B. L.
10.1101/2020.08.27.263988 — microbiology — Posted on 2020-08-27
605 Rethinking Remdesivir: Synthesis of Lipid Prodrugs that Substantially Enhance Anti-Coronavirus Activity
Schooley, R. T.; Carlin, A. F.; Beadle, J. R.; Valiaeva, N.; Zhang, X.-Q.; Garretson, A. F.; Smith, V. I.; Murphy, J. A.; Hostetler, K. Y.
10.1101/2020.08.26.269159 — microbiology — Posted on 2020-08-27
606 The immunodominant and neutralization linear epitopes for SARS-CoV-2
Lu, S.; Xie, X.-x.; Zhao, L.; Wang, B.; Zhu, J.; Yang, T.-r.; Yang, G.-w.; Ji, M.; Lv, C.-p.; Xue, J.; Dai, E.-h.; Fu, X.-m.; Liu, D.-q.; Zhang, L.; Hou, S.-j.; Yu, X.-l.; Wang, Y.-l.; Gao, H.-x.; Shi, X.-h.; Ke, C.-w.; Ke, B.-x.; Jiang, C.-g.; Liu, R.-t.
10.1101/2020.08.27.267716 — immunology — Posted on 2020-08-27
608 Low replication stress leads to specific replication timing advances associated to chromatin remodelling in cancer cells
Courtot, L.; Maric, C.; Bournique, E.; Guitton-Sert, L.; Madrid-Mencia, M.; Pancaldi, V.; Hoffmann, J.-S.; Cadoret, J.-C.; Bergoglio, V.
10.1101/2020.08.19.256883 — cancer biology — Posted on 2020-08-27
609 Targeting OCA-B/Pou2af1 blocks activated, autoreactive T cells in the pancreas and type-1 diabetes
Kim, H.; Perovanovic, J.; Shakya, A.; Shen, Z.; German, C. N.; Ibarra, A.; Jafek, J. L.; Lin, N.-P.; Evavold, B. D.; Chou, D. H.- C.; Jensen, P. E.; He, X.; Tantin, D.
10.1101/2020.02.06.937839 — immunology — Posted on 2020-08-27
614 Plasticity as an Underlying Mechanism of Tumor Heterogeneity in Breast Cancer
Akbar, M. W.; Isbilen, M.; Kucukkaraduman, B.; Demirkol Canli, S.; Dedeoglu, E.; Azizolli, S.; Cela, I.; Akcay, A. G.; Hakanoglu, H.; Gure, A. O.
10.1101/2020.03.11.987511 — cancer biology — Posted on 2020-08-27
617 Nonclassical nucleation of protein mesocrystals via oriented attachment
Van Driessche, A. E. S.; Van Gerven, N.; Joosten, R. R. M.; Ling, W. L.; Bacia, M.; Schoehn, G.; Sommerdijk, N. A. J. M.; Sleutel, M.
10.1101/2020.08.27.267013 — biochemistry — Posted on 2020-08-27
618 A sort-seq approach to the development of single fluorescent protein biosensors
Koberstein, J. N.; Stewart, M. L.; Mighell, T. L.; Smith, C. B.; Cohen, M. S.
10.1101/2020.08.21.261578 — biochemistry — Posted on 2020-08-27
619 Low XIST expression in Sertoli cells of Klinefelter syndrome patients caused the high susceptibility of these cells to an extra X chromosome
Zhao, L.; Li, P.; Yao, C.; Xing, X.; Yang, C.; Luo, J.; Ji, Z.; Tian, R.; Chen, H.; Zhu, Z.; Deng, Z.; Li, N.; Fang, J.; Sun, J.; Wang, C.; Zhou, Z.; Li, Z.
10.1101/2020.08.26.269423 — genomics — Posted on 2020-08-27
620 Novel combination of CRISPR-based gene drives eliminates resistance and localises spread
Faber, N. R.; McFarlane, G. R.; Gaynor, R. C.; Pocrnic, I.; Whitelaw, C. B. A.; Gorjanc, G.
10.1101/2020.08.27.266155 — genetics — Posted on 2020-08-27
623 Aberrant DJ-1 expression underlies L-type calcium channel hypoactivity in tuberous sclerosis complex and Alzheimer's disease
Niere, F.; Cacheaux, L. P.; Uneri, A.; Reynoldson, C.; Penaranda, J.; Taylor, W. C.; Craft, S.; Keene, C. D.; Ma, T.; Raab-Graham, K. F.
10.1101/2020.08.26.267260 — neuroscience — Posted on 2020-08-27
624 Cell-type, single-cell, and spatial signatures of brain-region specific splicing in postnatal development
Joglekar, A.; Przhibelskiy, A. D.; Mahfouz, A.; Collier, P.; Lin, S.; Schlusche, A. K.; Marrocco, J.; Williams, S. R.; Haase, B.; Hayes, A.; Chew, J. G.; Weisenfeld, N. I.; Wong, M. Y.; Stein, A. N.; Hardwick, S.; Hunt, T.; Bent, Z.; Fedrigo, O.; Sloan, S. A.; Risso, D.; Jarvis, E. D.; Flicek, P.; Luo, W.; Pitt, G. S.; Frankish, A.; Smit, A. B.; Ross, M. E.; Tilgner, H. U.
10.1101/2020.08.27.268730 — neuroscience — Posted on 2020-08-27
625 Auditory beat stimulation modulates memory-related single-neuron activity in the human medial temporal lobe
Derner, M.; Chaieb, L.; Dehnen, G.; Reber, T. P.; Borger, V.; Surges, R.; Staresina, B. P.; Mormann, F.; Fell, J.
10.1101/2020.08.27.268045 — neuroscience — Posted on 2020-08-27
629 Phenotypic distribution of the stem-like melanoma initiating state depends on CDKN2A status
Zhang, Y.; Hansen, M. M.; Hejna, M.; Weinberger, L. S.; Judson-Torres, R. L.; Judson-Torres, R. L.
10.1101/2020.08.26.269126 — cancer biology — Posted on 2020-08-27
630 A Molecular Taxonomy of Tumors Independent of Tissue-of-Origin
Nguyen, P. T.; Coetzee, S. G.; Lakeland, D. L.; Hazelett, D. J.
10.1101/2020.08.26.268987 — cancer biology — Posted on 2020-08-27
631 A biophysical and structural analysis of DNA binding by oligomeric hSSB1 (NABP2/OBFC2B)
El-Kamand, S.; Jergic, S.; Lawson, T.; Kariawasam, R.; Richard, D. J.; Cubeddu, L.; Gamsjaeger, R.
10.1101/2020.08.26.269084 — biochemistry — Posted on 2020-08-27
632 Toxoplasma gondii infections are associated with boldness towards lions in wild hyena hosts
Gering, E.; Laubach, Z. M.; Weber, P.; Hussey, G. S.; Lehmann, K. D. S.; Montgomery, T. M.; Turner, J. W.; Perng, W.; Pioon, M. O.; Holekamp, K. E.; Getty, T.
10.1101/2020.08.26.268805 — animal behavior and cognition — Posted on 2020-08-27
634 Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands
Roberts, B. S.; Partridge, C.; Moyers, B. A.; Agarwal, V.; Newberry, K. M.; Martin, B. K.; Shendure, J.; Myers, R. M.; Cooper, G. M.
10.1101/2020.08.26.269027 — genomics — Posted on 2020-08-27
635 Histone demethylome map reveals combinatorial gene regulatory functions in embryonic stem cells
Kumar, Y.; Tripathi, P.; Mehravar, M.; Bullen, M. J.; Pandey, V. K.; Hathiwala, D.; Kerenyi, M.; Woo, A.; Ghamari, A.; Cantor, A. B.; Wong, L. H.; Kim, J.; Glass, K.; Yuan, G.-C.; Pinello, L.; Orkin, S. H.; Das, P. P.
10.1101/2020.08.27.269514 — genomics — Posted on 2020-08-27
636 Underlying microevolutionary processes parallel macroevolutionary patterns in ancient Neotropical Mountains
Dantas-Queiroz, M. V.; Cacossi, T. d. C.; Leal, B. S. S.; Chaves, C. J. N.; Vasconcelos, T. N. C.; Versieux, L. d. M.; Palma-Silva, C.
10.1101/2020.08.26.268870 — evolutionary biology — Posted on 2020-08-27
637 Divergent DNA methylation signatures underlying X chromosome regulation in marsupials and eutherians
Singh, D.; Sun, D.; King, A. G.; Alquezar-Planas, D. E.; Johnson, R. N.; Alvarez-Ponce, D.; Yi, S. V.
10.1101/2020.08.26.269068 — evolutionary biology — Posted on 2020-08-27
641 Corticosteroids and cellulose purification improve respectively the in vivo translation and vaccination efficacy of self-amplifying mRNAs
Zhong, Z.; Mc Cafferty, S.; Opsomer, L.; Wang, H.; Huysmans, H.; De Temmerman, J.; Lienenklaus, S.; Portela Catani, J. P.; Combes, F.; Sanders, N.
10.1101/2020.08.26.268706 — immunology — Posted on 2020-08-27
643 Metformin enhances anti-mycobacterial responses by educating immunometabolic circuits of CD8+ T cells
Bohme, J.; Martinez, N.; Li, S.; Lee, A.; Marzuki, M.; Tizazu, A.; Ackart, D.; Frenkel, J.; Todd, A.; Lachmandas, E.; Lum, J.; Shihui, F.; Ng, T. P.; Lee, B.; Larbi, A.; Netea, M.; Basaraba, R.; van Crevel, R.; Newell, E.; Kornfeld, H.; Singhal, A.
10.1101/2020.08.26.269217 — immunology — Posted on 2020-08-27
644 FAM13A regulates maturation and effector functions of natural killer cells
Zeng, N.; Theresine, M.; Capelle, C.; Patil, N.; Masquelier, C.; Davril, C.; Baron, A.; Coowar, D.; Dervillez, X.; Poli, A.; Leonard, C.; Balling, R.; Ollert, M.; Zimmer, J.; He, F. Q.
10.1101/2020.08.26.268490 — immunology — Posted on 2020-08-27
645 Shape coding in occipito-temporal cortex relies on object silhouette, curvature and medial-axis
Papale, P.; Leo, A.; Handjaras, G.; Cecchetti, L.; Pietrini, P.; Ricciardi, E.
10.1101/814251 — neuroscience — Posted on 2020-08-27
646 Imbalance of flight-freeze responses and their cellular correlates in the Nlgn3-/y rat model of autism
Anstey, N. J.; Kapgal, V.; Tiwari, S.; Watson, T. C.; Toft, A. K.; Dando, O. R.; Inkpen, F. H.; Baxter, P. S.; Kozic, Z.; Jackson, A. D.; He, X.; Nawaz, M. S.; Kayenaat, A.; Bhattacharya, A.; Wyllie, D. J.; Chattarji, S.; Wood, E. R.; Hardt, O.; Kind, P. C.
10.1101/2020.08.27.267880 — neuroscience — Posted on 2020-08-27
647 EntireAxon: Deep learning deciphers four distinct patterns of axonal degeneration
Palumbo, A.; Gruening, P.; Landt, S. K.; Heckmann, L. E.; Bartram, L.; Pabst, A.; Flory, C.; Ikhsan, M.; Pietsch, S.; Schulz, R.; Kren, C.; Koop, N.; Boltze, J.; Madany Mamlouk, A.; Zille, M.
10.1101/2020.08.26.269092 — neuroscience — Posted on 2020-08-27
648 Strengthening marine amphipod DNA barcode libraries for environmental monitoring
PrasannaKumar, C.; Manikantan, G.; Vijaylaxmi, J.; Gunalan, B.; Manokaran, S.
10.1101/2020.08.26.268896 — zoology — Posted on 2020-08-27
655 Imaging the Transmembrane and Transendothelial Sodium Gradients in Gliomas
Khan, M. H.; Walsh, J. J.; Mihailovic, J. M.; Mishra, S. K.; Coman, D.; Hyder, F.
10.1101/2020.08.26.268839 — cancer biology — Posted on 2020-08-27
660 KRSA: Network-based Prediction of Differential Kinase Activity from Kinome Array Data
DePasquale, E. A.; Alganem, K.; Bentea, E.; Nawreen, N.; McGuire, J.; Naji, F.; Hilhorst, R.; Meller, J.; McCullumsmith, R.
10.1101/2020.08.26.268581 — bioinformatics — Posted on 2020-08-27
661 Antibody-based delivery of Interleukin-9 to neovascular structures: therapeutic evaluation in cancer and arthritis
Gouyou, B.; Ongaro, T.; Cazzamalli, S.; De Luca, R.; Kerschenmeyer, A.; Valet, P.; Villa, A.; Neri, D.; Matasci, M.
10.1101/2020.08.26.268292 — bioengineering — Posted on 2020-08-27
666 Fine-scale landscape genetics unveiling contemporary asymmetric movement of red panda (Ailurus fulgens) in Kangchenjunga landscape, India
Dalui, S.; Khatri, H.; Singh, S. K.; Basu, S.; Ghosh, A.; Mukherjee, T.; Sharma, L. K.; Singh, R.; Chandra, K.; Thakur, M.
10.1101/2020.08.26.268532 — genetics — Posted on 2020-08-27
667 Gene disruption by structural mutations drives selection in US rice breeding over the last century
Vaughn, J. N.; Korani, W.; Stein, J. C.; Edwards, J. D.; Peterson, D. G.; Simpson, S. A.; Youngblood, R. C.; Grimwood, J.; Ware, D. H.; McClung, A. M.; Scheffler, B. E.
10.1101/2020.08.26.268342 — genetics — Posted on 2020-08-27
669 The sources of sex differences in aging in annual fishes
Reichard, M.; Blazek, R.; Zak, J.; Kacer, P.; Tomasek, O.; Albrecht, T.; Cellerino, A.; Polacik, M.
10.1101/2020.08.25.266411 — evolutionary biology — Posted on 2020-08-27
671 Natural resistance to worms exacerbates bovine tuberculosis severity independently of worm coinfection
Ezenwa, V.; Budischak, S.; Buss, P.; Seguel, M.; Luikart, G.; Jolles, A.; Sakamoto, K.
10.1101/2020.08.26.262683 — ecology — Posted on 2020-08-27
672 Parental genome unification is highly erroneous in mammalian embryos
Cavazza, T.; Politi, A. Z.; Aldag, P.; Baker, C.; Elder, K.; Blayney, M.; Lucas-Hahn, A.; Niemann, H.; Schuh, M.
10.1101/2020.08.27.269779 — developmental biology — Posted on 2020-08-27
674 Persistent broken chromosome inheritance drives genome instability
Pai, C.-C.; Durley, S. C.; Cheng, W.-C.; Chiang, N.-Y.; Wee, B.-Y.; Walker, C.; Kearsey, S. E.; Buffa, F.; Murray, J. M.; Humphrey, T. C.
10.1101/2020.08.26.268565 — molecular biology — Posted on 2020-08-27
679 Imaging meningeal inflammation in CNS autoimmunity identifies a therapeutic role for BTK inhibition
Bhargava, P.; Kim, S.; Reyes, A. A.; Grenningloh, R.; Boshcert, U.; Absinta, M.; Pardo-Villamizar, C.; Van Zijl, P.; Zhang, J.; Calabresi, P.
10.1101/2020.08.26.268250 — neuroscience — Posted on 2020-08-27
680 Temporal uncertainty affects the visual processing of predicted stimulus properties
Nara, S.; Lizarazu, M.; Richter, C. G.; Dima, D. C.; Bourguignon, M.; Molinaro, N.
10.1101/2020.08.26.265884 — neuroscience — Posted on 2020-08-27
682 The circadian oscillator analysed at the single-transcript level
Phillips, N. E.; Hugues, A.; Yeung, J.; Durandau, E.; Nicolas, D.; Naef, F.
10.1101/2020.08.26.268201 — systems biology — Posted on 2020-08-27
683 Comparative transcriptomics identifies differences in the regulation of the floral transition between Arabidopsis and Brassica rapa cultivars
Calderwood, A.; Hepworth, J.; Woodhouse, S.; Bilham, L.; Jones, M.; Tudor, E. J.; Ali, M.; Dean, C.; Wells, R.; Irwin, J.; Morris, R. J.
10.1101/2020.08.26.266494 — plant biology — Posted on 2020-08-27
686 Specific decorations of 17-hydroxygeranyllinalool diterpene glycosides solve the autotoxicity problem of chemical defense in Nicotiana attenuata
Heiling, S.; Llorca, L. C.; Li, J.; Gase, K.; Schmidt, A.; Schaefer, M.; Schneider, B.; Halitschke, R.; Gaquerel, E.; Baldwin, I. T.
10.1101/2020.08.26.267690 — plant biology — Posted on 2020-08-27
687 Low sperm to egg ratio required for successful in vitro fertilisation in a pair-spawning teleost, Senegalese sole (Solea senegalensis)
Ramos-Judez, S.; Gonzalez-Lopez, W. A.; Huayanay Ostos, J.; Cota Mamani, N.; Marrero Aleman, C.; Beirao, J.; Duncan, N.
10.1101/2020.08.26.267740 — physiology — Posted on 2020-08-27
689 3D Deconvolution Processing for STEM Cryo-Tomography
Waugh, B.; Wolf, S. G.; Fass, D.; Branlund, E.; Kam, T.; Sedat, J.; Elbaum, M.
10.1101/2020.08.26.267732 — biophysics — Posted on 2020-08-27
691 Integrated Collection of Stem Cell Bank data, a data portal for standardized stem cell information
Chen, Y.; Sakurai, K.; Maeda, S.; Masui, T.; Okano, H.; Dewender, J.; Seltmann, S.; Kurtz, A.; Masuya, H.; Nakamura, Y.; Sheldon, M.; Schneider, J.; Stacey, G.; Panina, Y.; Fujibuchi, W.
10.1101/2020.08.26.263830 — bioinformatics — Posted on 2020-08-27
694 The heterogeneous landscape and early evolution of pathogen-associated CpG dinucleotides in SARS-CoV-2
Di Gioacchino, A.; Sulc, P.; Komarova, A. V.; Greenbaum, B. D.; Monasson, R.; Cocco, S.
10.1101/2020.05.06.074039 — genomics — Posted on 2020-08-27
695 Trait-based responses to forestry and animal husbandry modify long-term changes in forest understories
Happonen, K.; Muurinen, L.; Virtanen, R.; Kaakinen, E.; Grytnes, J.-A.; Kaarlejärvi, E.; Parisot, P.; Wolff, M.; Maliniemi, T.
10.1101/2020.04.30.069708 — ecology — Posted on 2020-08-27
699 Comparative regulomics reveals pervasive selection on gene dosage following whole genome duplication
Gillard, G. B.; Groenvold, L.; Roesaeg, L. L.; Holen, M. M.; Monsen, O.; Koop, B. F.; Rondeau, E. B.; Gundappa, M. K.; Mendoza, J.; Macqueen, D.; Rohlfs, R. V.; Sandve, S. R.; Hvidsten, T. R.
10.1101/2020.07.20.212316 — evolutionary biology — Posted on 2020-08-27
705 Potential For Applying Continuous Directed Evolution To Plant Enzymes
Garcia-Garcia, J. D.; Joshi, J.; Patterson, J. A.; Trujillo-Rodriguez, L.; Reisch, C. R.; Javanpour, A. A.; Liu, C. C.; Hanson, A. D.
10.1101/2020.08.26.265678 — synthetic biology — Posted on 2020-08-27
709 Network asynchrony underlying increased broadband gamma power
Guyon, N.; Zacharias, L. R.; de Oliveira, E. F.; Kim, H.; Leite, J. P.; Lopes Aguiar, C.; Carlen, M.
10.1101/2020.08.26.265439 — neuroscience — Posted on 2020-08-27
710 Optimization and scaling of patient-derived brain organoids uncovers deep phenotypes of disease
Shah, K.; Bedi, R.; Rogozhnikov, A.; Ramkumar, P.; Tong, Z.; Rash, B.; Stanton, M.; Sorokin, J.; Apaydin, C.; Batarse, A.; Bergamaschi, J.; Blattner, R.; Brown, S.; Bosshardt, A.; Castrillo, C.; Dang, B.; Drusinsky, S.; Enriquez, L.; Grayson, D.; Hilliard, J.; Hsu, P.-K.; Johnson, C.; Jones, R.; Lash, A.; Lee, E.; Li, K.; McKay, A.; Mount, E.; Nicola, J.; Oumzil, I.; Paek, J.; Pascoe, D.; Piepho, A.; Poust, S.; Quang, D.; Schultz, M.; Sims, J.; Taylor, P.; Treiman, G.; Wueseke, O.; Young, N.; Pollen, A. A.; Flanzer, D.; Chao, D.; Skibinski, G.; Kato, S.; Escola, S.
10.1101/2020.08.26.251611 — neuroscience — Posted on 2020-08-27
714 EEG Alpha Power Predicts the Temporal Sensitivity of Multisensory Integration
London, R. E.; Benwell, C. S.; Cecere, R.; Quak, M.; Thut, G.; Talsma, D.
10.1101/2020.08.26.268144 — neuroscience — Posted on 2020-08-27
716 SARS-CoV-2 genomic and quasispecies analyses in cancer patients reveal relaxed intrahost virus evolution
Siqueira, J.; Goes, L. R.; Alves, B. M.; de Carvalho, P. S.; Cicala, C.; Arthos, J.; Viola, J. P. B.; de Melo, A. C.; Soares, M. A.; INCA COVID-19 Task Force (names of participants listed in the acknowledgements section number of cha,
10.1101/2020.08.26.267831 — microbiology — Posted on 2020-08-26
717 An inside look at a biofilm: Pseudomonas aeruginosa flagella bio-tracking
Ozer, E.; Yaniv, K.; Shetrit, E.; Boyarski, A.; Meijler, M.; Berkovich, R.; Kushmaro, A.; Alfonta, L.
10.1101/2020.08.26.267963 — microbiology — Posted on 2020-08-26
718 Population Genomics of Plasmodium vivax in Panama to Assess the Risk of Case Importation on Malaria Elimination
Buyon, L. E.; Santamaria, A. M.; Early, A. M.; Quijada, M.; Barahona de Mosca, I.; Lasso, J.; Avila, M.; Volkman, S. K.; Marti, M.; Neafsey, D. E.; Obaldia, N.
10.1101/2020.08.26.267823 — microbiology — Posted on 2020-08-26
720 Heterologous expression of cryptomaldamide in a cyanobacterial host
Taton, A.; Ecker, A.; Diaz, B.; Moss, N. A.; Anderson, B.; Reher, R.; Leao, T. F.; Simkovsky, R.; Dorrestein, P. C.; Gerwick, L.; Gerwick, W. H.; Golden, J. W.
10.1101/2020.08.26.267179 — synthetic biology — Posted on 2020-08-26
721 Molecular dynamics reveals complex compensatory effects of ionic strength on the SARS-CoV-2 Spike/hACE-2 interaction
Souza, A. S. d.; Rivera, J. D.; Medeiros, V.; Ge, P.; Souza, R. F. d.; Farah, C. S.; Ulrich, H.; Marana, S. R.; Kopke Salinas, R.; Guzzo, C. R.
10.1101/2020.08.25.267351 — bioinformatics — Posted on 2020-08-26
723 Taking the next-gen step: comprehensive antimicrobial resistance detection from Burkholderia pseudomallei
Madden, D. E.; Webb, J. R.; Steinig, E. J.; Currie, B. J.; Price, E. P.; Sarovich, D. S.
10.1101/720607 — genomics — Posted on 2020-08-26
724 A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development
Crane-Smith, Z.; Schoenebeck, J.; Graham, K. A.; Devenney, P. S.; Rose, L.; Ditzell, M.; Anderson, E.; Thomson, J. I.; Klenin, N.; Kurrasch, D. M.; Lettice, L. A.; Hill, R.
10.1101/794198 — developmental biology — Posted on 2020-08-26
726 Alpha-ketoglutarate inhibits Regulatory T cell differentiation by coupling lipidome remodelling to mitochondrial metabolism
Matias, M. I.; Yong, C. S.; Foroushani, A.; Sezgin, E.; Levental, K. R.; Talebi, A.; Mongellaz, C.; Dehair, J.; Wong, M.; Kinet, S.; Zimmermann, V. S.; Levental, I.; Yvan-Charvet, L.; Swinnen, J. v.; Muljo, S.; Tardito, S.; Dardalhon, V.; Taylor, N.
10.1101/2020.08.24.256560 — immunology — Posted on 2020-08-26
727 Cortical music selectivity does not require musical training
Boebinger, D. L.; Norman-Haignere, S. V.; McDermott, J. H.; Kanwisher, N.
10.1101/2020.01.10.902189 — neuroscience — Posted on 2020-08-26
728 Boosting L-type Ca2+ channel activity in tuberous sclerosis mitigates excess glutamate receptors and seizures
Niere, F.; Cacheaux, L. P.; Klorig, D. C.; Taylor, W. C.; Smith, T.; Godwin, D. W.; Raab-Graham, K. F.
10.1101/2020.08.26.269209 — neuroscience — Posted on 2020-08-26
730 RNA-binding protein network alteration causes aberrant axon branching and growth phenotypes in FUS ALS mutant motoneurons
Garone, M. G.; Birsa, N.; Rosito, M.; Salaris, F.; Mochi, M.; de Turris, V.; Nair, R. R.; Cunningham, T. J.; Fisher, E. M. C.; Fratta, P.; Rosa, A.
10.1101/2020.08.26.268631 — neuroscience — Posted on 2020-08-26
731 Characterization of novel pollen-expressed transcripts reveals their potential roles in pollen heat stress response in Arabidopsis thaliana.
Rutley, N.; Poidevin, L.; Doniger, T.; Tillet, R. L.; Rath, A.; Forment, J.; Schlauch, K.; Luria, G.; Ferrando, A.; Harper, J. F.; Miller, G.
10.1101/2020.08.20.258764 — plant biology — Posted on 2020-08-26
732 Orthosteric-allosteric dual inhibitors of PfHT1 as selective anti-malarial agents
Huang, J.; Yuan, Y.; Zhao, N.; Pu, D.; Tang, Q.; Zhang, S.; Luo, S.; Yang, X.; Wang, N.; Xiao, Y.; Zhang, T.; Liu, Z.; Sakata-Kato, T.; Jiang, X.; Kato, N.; Yan, N.; Yin, H.
10.1101/2020.08.25.260232 — pharmacology and toxicology — Posted on 2020-08-26
734 Deep learning enables the design of functional de novo antimicrobial proteins
Caceres-Delpiano, J.; Ibanez, R.; Alegre, P.; Sanhueza, C.; Paz, R.; Correa, S.; Retamal, P.; Jimenez, J. C.; Alvarez, L.
10.1101/2020.08.26.266940 — bioengineering — Posted on 2020-08-26
735 Dual RNAseq highlights the kinetics of skin microbiome and fish host responsiveness to bacterial infection
Le Luyer, J.; Schull, Q.; Auffret, P.; Lopez, P.; Crusot, M.; Belliard, C.; Basset, C.; Carradec, Q.; Poulain, J.; Planes, S.; Saulnier, D.
10.1101/2020.08.26.247221 — genomics — Posted on 2020-08-26
739 Adhesion-mediated heterogeneous actin organization governs apoptotic cell extrusion
Le, A. P.; Rupprecht, J.-F.; Mege, R.-M.; Toyama, Y.; Lim, C. T.; Ladoux, B.
10.1101/2020.08.26.268094 — cell biology — Posted on 2020-08-26
740 Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis
Johnson, B. A.; Xie, X.; Kalveram, B.; Lokugamage, K. G.; Muruato, A.; Zou, J.; Zhang, X.; Juelich, T.; Smith, J. K.; Zhang, L.; Schindewolf, C.; Vu, M. N.; Vanderheiden, A.; Plante, J. A.; Plante, K. S.; Lee, B.; Weaver, S.; Suthar, M.; Routh, A. L.; Ren, P. L.; Ku, Z.; An, Z.; Debbink, K.; Shi, P. Y.; Freiberg, A. N.; Menachery, V. D.
10.1101/2020.08.26.268854 — microbiology — Posted on 2020-08-26
742 Induction of selective cell death in HIV-1-infected cells by DDX3 inhibitors leads to depletion of the inducible reservoir
Rao, S.; Lungu, C.; Steijaert, T. H.; Crespo, R.; Palstra, R.-J.; Prins, H. A. B.; van Ijcken, W.; Rokx, C.; Mueller, Y. M.; Van Kampen, J. J. A.; Verbon, A.; Katsikis, P. D.; Boucher, C. A. B.; Gruters, R. A.; Mahmoudi, T.
10.1101/2020.08.26.266726 — microbiology — Posted on 2020-08-26
743 Scanning ion conductance microscopy reveals differences in the ionic environments of gram positive and negative bacteria
Cremin, K.; Jones, B.; Teahan, J.; Meloni, G. N.; Perry, D.; Zerfass, C.; Asally, M.; soyer, o. s.; Unwin, P. R.
10.1101/2020.08.26.267849 — microbiology — Posted on 2020-08-26
744 Differences in structure and hibernation mechanism highlight diversification of the microsporidian ribosome.
Ehrenbolger, K.; Jespersen, N.; Sharma, H.; Sokolova, Y. Y.; Tokarev, Y. S.; Vossbrinck, C. R.; Barandun, J.
10.1101/2020.08.26.265892 — microbiology — Posted on 2020-08-26
748 Genomic and kinetic analysis of novel Nitrospinae enriched by cell sorting
Mueller, A. J.; Jung, M.-Y.; Strachan, C. R.; Herbold, C. W.; Kirkegaard, R. H.; Wagner, M.; Daims, H.
10.1101/2020.06.09.141952 — microbiology — Posted on 2020-08-26
751 Predicting Alzheimer's disease progression trajectory and clinical subtypes using machine learning
Satone, V. K.; Kaur, R.; Dadu, A.; Leonard, H.; Iwaki, H.; Makarious, M. B.; Sargent, L.; Daneshmand, A.; Scholz, S. W.; Singleton, A. B.; Nalls, M. A.; Campbell, R. H.; Faghri, F.; Alzheimers Disease Neuroimaging Initiative,
10.1101/792432 — neuroscience — Posted on 2020-08-26
753 Early life stress targets the transcriptional signature and functional properties of voltage gated-sodium (Nav) channels in hippocampal NG2+ glia.
Treccani, G.; Yigit, H.; Lingner, T.; Schleussner, V.; Wennstrom, M.; Herzog, D. P.; Fricke, M.; Wegener, G.; Mittmann, T.; Trotter, J.; Muller, M.
10.1101/2020.08.19.257113 — neuroscience — Posted on 2020-08-26
754 How widespread was the Tapanuli orangutan and what led to its decline?
Meijaard, E.; Ni'matullah, S.; Dennis, R.; Sherman, J.; Onrizal, O.; Wich, S. A.
10.1101/2020.08.11.246058 — zoology — Posted on 2020-08-26
755 AI aided design of epitope-based vaccine for the induction of cellular immune responses against SARS-CoV-2
Mazzocco, G.; Niemiec, I.; Myronov, A.; Skoczylas, P.; Kaczmarczyk, J.; Sanecka-Duin, A.; Gruba, K.; Krol, P.; Drwal, M.; Szczepanik, M.; Pyrc, K.; Stepniak, P.
10.1101/2020.08.26.267997 — bioinformatics — Posted on 2020-08-26
756 Identification of a polymorphism in the N gene of SARS-CoV-2 that adversely impacts detection by a widely-used RT-PCR assay
Vanaerschot, M.; Mann, S. A.; Webber, J. T.; Kamm, J.; Bell, S. M.; Bell, J.; Hong, S. N.; Nguyen, M. P.; Chan, L. Y.; Bhatt, K. D.; Tan, M.; Detweiler, A. M.; Espinosa, A.; Wu, W.; Batson, J.; Dynerman, D.; CLIAHUB Consortium, ; Wadford, D. A.; Puschnik, A.; Neff, N.; Ahyong, V.; Miller, S.; Ayscue, P.; Tato, C. M.; Paul, S.; Kistler, A.; DeRisi, J. L.; Crawford, E. D.
10.1101/2020.08.25.265074 — molecular biology — Posted on 2020-08-26
757 A unique view of SARS-CoV-2 through the lens of ORF8 protein
Hassan, S. S.; Ghosh, S.; Attrish, D.; Choudhury, P. P.; Seyran, M.; Pizzol, D.; Adadi, P.; Abd El Aziz, T. M.; Soares, A.; Kandimalla, R.; Lundstrom, K.; Tambuwala, M.; Aljabali, A. A.; Lal, A.; Azad, G. K.; Uversky, V. N.; Sherchan, S. P.; Baetas-da-Cruz, W.; Uhal, B.; Rezaei, N.; Brufsky, A.
10.1101/2020.08.25.267328 — molecular biology — Posted on 2020-08-26
758 Multi-species ELISA for the detection of antibodies against SARS-CoV-2 in animals
Wernike, K.; Aebischer, A.; Michelitsch, A.; Hoffmann, D.; Freuling, C.; Balkema-Buschmann, A.; Graaf, A.; Mueller, T.; Osterrieder, N.; Rissmann, M.; Rubbenstroth, D.; Schoen, J.; Schulz, C.; Trimpert, J.; Ulrich, L.; Volz, A.; Mettenleiter, T.; Beer, M.
10.1101/2020.08.26.266825 — microbiology — Posted on 2020-08-26
759 Inhibiting coronavirus replication in cultured cells by chemical ER stress
Shaban, M. S.; Mueller, C.; Mayr-Buro, C.; Weiser, H.; Albert, B. V.; Weber, A.; Linne, U.; Hain, T.; Babayev, I.; Karl, N.; Hofmann, N.; Becker, S.; Herold, S.; Schmitz, M. L.; Ziebuhr, J.; Kracht, M.
10.1101/2020.08.26.266304 — immunology — Posted on 2020-08-26
765 Use of High Pressure NMR Spectroscopy to Rapidly Identify Proteins with Internal Ligand-Binding Voids
Gagne, D.; Azad, R.; Edupuganti, U. R.; Williams, J.; Aramini, J. M.; Akasaka, K.; Gardner, K. H.
10.1101/2020.08.25.267195 — biophysics — Posted on 2020-08-26
767 DNA methylation landscapes of matched primary and recurrent high grade serous ovarian cancers are preserved throughout disease progression and chemoresistance.
Gull, N.; Jones, M. R.; Peng, P.-C.; Coetzee, S. G.; Chedraoui Silva, T.; Plummer, J. T.; Reyes, A. L.; Davis, B. D.; Chen, S.; Lawrenson, K.; Lester, J.; Walsh, C.; Rimel, B. J.; Li, A. J.; Cass, I.; Berg, Y.; Govindavari, J.-P. B.; Rutgers, J. K.; Karlan, B. Y.; Berman, B. P.; Gayther, S.
10.1101/2020.08.25.267161 — genomics — Posted on 2020-08-26
768 MicroRNA variants and HLA-miRNA interactions are novel rheumatoid arthritis susceptibility factors
Guo, S.; Jin, Y.; Zhou, J.; Zhu, Q.; Jiang, T.; Bian, Y.; Zhang, R.; Chang, C.; Xu, L.; Shen, J.; Zheng, X.; Shen, Y.; Qin, Y.; Chen, J.; Tang, X.; Cheng, P.; Ding, Q.; Zhang, Y.; Liu, J.; Cheng, Q.; Guo, M.; Liu, Z.; Qiu, W.; Qian, Y.; Sun, Y.; Shen, Y.; Nie, H.; Schrodi, S. J.; He, D.
10.1101/2020.08.25.264515 — genetics — Posted on 2020-08-26
771 Musashi regulates follicle stem cell maintenance and epithelial niche homeostasis in the Drosophila ovary
Siddall, N. A.; Casagranda, F.; Dominado, N.; Heaney, J.; Sutherland, J. M.; McLaughlin, E. A.; Hime, G. R.
10.1101/2020.08.25.265769 — developmental biology — Posted on 2020-08-26
773 Predicting transcriptional responses to cold stress across plant species
Meng, X.; Liang, Z.; Dai, X.; Zhang, Y.; Mahboub, S.; Ngu, D. W.; Roston, R. L.; Schnable, J.
10.1101/2020.08.25.266635 — plant biology — Posted on 2020-08-26
775 Multi-omics phenotyping of the gut-liver axis allows health risk predictability from in vivo subchronic toxicity tests of a low-dose pesticide mixture
Mesnage, R.; Teixeira, M.; Mandrioli, D.; Falcioni, L.; Ducarmon, Q. R.; Zwittink, R. D.; Amiel, C.; Panoff, J.-M.; Bourne, E.; Savage, E.; Mein, C. A.; Belpoggi, F.; Antoniou, M.
10.1101/2020.08.25.266528 — pharmacology and toxicology — Posted on 2020-08-26
777 Integrative genomics of the mammalian alveolar macrophage response to intracellular mycobacteria
Hall, T. J.; Mullen, M. P.; McHugo, G. P.; Killick, K. E.; Ring, S. C.; Berry, D. P.; Correia, C. N.; Browne, J. A.; Gordon, S. V.; MacHugh, D. E.
10.1101/2020.08.25.266668 — genomics — Posted on 2020-08-26
780 Prenatal Stress Dysregulates Resting-State Functional Connectivity and Sensory Motifs
Jafari, Z.; Rezaei, Z.; Afrashteh, N.; Torabi, R.; Singh, S.; Kolb, B. E.; Davidsen, J.; Mohajerani, M. H.
10.1101/2020.08.26.268359 — neuroscience — Posted on 2020-08-26
786 Effective variant filtering and expected candidate variant yield in studies of rare human disease
Pedersen, B. S.; Brown, J. M.; Dashnow, H.; Wallace, A. D.; Velinder, M.; Tvrdik, T.; Mao, R.; Best, H. D.; Bayrak-Toydemir, P.; Quinlan, A. R.
10.1101/2020.08.13.249532 — bioinformatics — Posted on 2020-08-26
787 Hypoxia-inducible lipid droplet-associated interacts with DGAT1 and promotes lipid storage in hepatocytes
de la Rosa Rodriguez, M.; Gemmink, A.; van Weeghel, M.; Aoun, M. L.; Singh, R.; Borst, J. W.; Kersten, S.; Warnecke, C.
10.1101/2020.02.26.966374 — biochemistry — Posted on 2020-08-26
788 Globins in the marine Annelid Platynereis dumerilii shed new light on hemoglobin evolution in Bilaterians
Song, S.; Starunov, V. V.; Bailly, X.; Ruta, C.; Kerner, P.; Cornelissen, A. J.; Balavoine, G.
10.1101/789214 — evolutionary biology — Posted on 2020-08-26
793 Recombinant SARS-CoV-2 RBD molecule with a T helper epitope as a built in adjuvant induces strong neutralization antibody response
Su, Q.; Zou, Y.; Yi, Y.; Shen, L.; Ye, X.; Zhang, Y.; Wang, H.; Ke, H.; Song, J.; Hu, K.; Cheng, B.; Qiu, F.; Yu, P.; Zhou, W.; Cao, L.; Bi, S.; Wu, G.; Gao, G. F.; Zheng, J.
10.1101/2020.08.21.262188 — bioengineering — Posted on 2020-08-26
794 Transport mechanism of class-3 P4 ATPase lipid flippases
Bai, L.; You, Q.; Jain, B. K.; Kovach, A.; Graham, T. R.; Li, H.
10.1101/2020.08.25.266742 — biochemistry — Posted on 2020-08-26
795 Quantitative data independent acquisition glycoproteomics of sparkling wine
Pegg, C. L.; Phung, T. K.; Caboche, C. H.; Niamsuphap, S.; Bern, M.; Howell, K.; Schulz, B. L.
10.1101/2020.06.09.141226 — biochemistry — Posted on 2020-08-26
796 A CRISPR Screen Identifies Myc-associated Zinc Finger Protein (MAZ) as an Insulator Functioning at CTCF boundaries in Hox Clusters
Ortabozkoyun Kara, H.; Huang, P.-Y.; Cho, H.; Narendra, V.; LeRoy, G.; Skok, J. A.; Tsirigos, A.; Mazzoni, E. O.; Reinberg, D.
10.1101/2020.08.25.267237 — biochemistry — Posted on 2020-08-26
797 Global and Local Mutations in Bangladeshi SARS-CoV-2 Genomes
Hasan, M. M.; Das, R.; Rasheduzzaman, M.; Hussain, M. H.; Muzahid, N. H.; Salauddin, A.; Rumi, M. H.; Rashid, S. M. M.; Siddiki, A. Z.; Mannan, A.
10.1101/2020.08.25.267658 — genomics — Posted on 2020-08-26
798 Visualization of individual cell division history in complex tissues
Denoth-Lippuner, A.; Jaeger, B. N.; Liang, T.; Chie, S. E.; Royall, L. N.; Kruse, M.; Simons, B. D.; Jessberger, S.
10.1101/2020.08.26.266171 — cell biology — Posted on 2020-08-26
799 Quantifying and modelling the acquisition and retention of lumpy skin disease virus by haematophagus insects reveals clinically but not subclinically-affected cattle are promoters of viral transmission and key targets for control of disease outbreaks.
Sanz-Bernardo, B.; Haga, I. R.; Wijesiriwardana, N.; Basu, S.; Larner, W.; Diaz, A. V.; Langlands, Z.; Denison, E.; Stoner, J.; White, M.; Sanders, C.; Hawes, P. C.; Wilson, A. J.; Atkinson, J.; Batten, C.; Alphey, L.; Darpel, K. E.; Gubbins, S.; Beard, P. M.
10.1101/2020.06.18.154252 — microbiology — Posted on 2020-08-26
800 Signal Peptide of HIV-1 Envelope Functions to Modulate Glycosylation Impacting Exposure of V1V2 Epitopes
Upadhyay, C.; Feyznezhad, R.; Cao, L.; Chan, K.-W.; Liu, K.; Yang, W.; Zhang, H.; Yolitz, J.; Arthos, J.; Nadas, A.; Kong, X.-P.; Zolla-Pazner, S.; Hioe, C. E.
10.1101/2020.07.21.212183 — microbiology — Posted on 2020-08-26
802 Highly potent anti-SARS-CoV-2 multi-DARPin therapeutic candidates
Walser, M.; Rothenberger, S.; Hurdiss, D. L.; Schlegel, A.; Calabro, V.; Fontaine, S.; Villemagne, D.; Paladino, M.; Hospodarsch, T.; Neculcea, A.; Cornelius, A.; Schildknecht, P.; Matzner, M.; Haenggi, M.; Franchini, M.; Kaufmann, Y.; Schlegel, I.; Iss, C.; Loser, T.; Mangold, S.; Herzog, C.; Schiegg, D.; Reichen, C.; Radom, F.; Bosshart, A.; Lehmann, A.; Haeuptle, M. A.; Zuercher, A.; Vagt, T.; Sigrist, G.; Straumann, M.; Proba, K.; Veitonmaki, N.; Dawson, K. M.; Zitt, C.; Mayor, J.; Ryter, S.; Lyoo, H.; Wang, C.; Li, W.; Drulyte, I.; Binz, H. K.; de Waal, L.; Stittelaar, K. J.; Lewis, S.; S
10.1101/2020.08.25.256339 — immunology — Posted on 2020-08-26
808 A molecular approach to studying Hymenoptera diets using polistine wasps
Lefort, M.-C.; Beggs, J. R.; Glare, T. R.; Saunders, T. E.; Doyle, E. J.; Boyer, S.
10.1101/2020.04.06.024422 — ecology — Posted on 2020-08-26
810 Clustering and reverse transcription of HIV-1 genomes in nuclear niches of macrophages
Rensen, E.; Mueller, F.; Scoca, V.; Parmar, J.; Souque, P.; Zimmer, C.; Di Nunzio, F.
10.1101/2020.04.12.038067 — microbiology — Posted on 2020-08-26
811 Morphologic Classification and Automatic Diagnosis of Bacterial Vaginosisby Deep Neural Networks
Wang, Z.; Zhang, L.; Wang, Y.; Wang, Y.; Liu, Z.; Bai, H.; Wu, W.; Mo, W.; An, R.; Li, J.; Li, N.; Li, P.; Zeng, X.; Rui, C.; Fan, C.; Geng, L.; Liu, X.; Zhao, M.; Zhu, W.; Qi, L.; Qiao, Q.; Wang, Z.; Si, Y.; Feng, A.; Li, M.; Zhang, Q.; Wang, M.; Liao, Q.; Xu, W.; Yang, Z.; Cao, Y.
10.1101/2020.05.20.101055 — microbiology — Posted on 2020-08-26
814 Informed dispersal of the dandelion
Seale, M.; Zhdanov, O.; Cummins, C.; Kroll, E.; Blatt, M. R.; Zare-Behtash, H.; Busse, A.; Mastropaolo, E.; Viola, I. M.; Nakayama, N.
10.1101/542696 — plant biology — Posted on 2020-08-26
815 The case for using Mapped Exonic Non-Duplicate (MEND) read counts in RNA-Seq experiments: examples from pediatric cancer datasets
Beale, H. C.; Roger, J.; Cattle, M.; McKay, L.; Thomson, D. K. A.; Learned, K.; Lyle, G.; Kephart, E.; Currie, R.; Lam, D. L.; Sanders, L.; Pfeil, J.; Vivian, J.; Bjork, I.; Salama, S.; Haussler, D.; Vaske, O.
10.1101/716829 — genomics — Posted on 2020-08-26
816 The Multivariate Genome-wide Architecture of Interrelated Literacy, Language and Working Memory Skills Reveals Distinct Etiologies
Shapland, C. Y.; Verhoef, E.; Davey Smith, G.; Fisher, S. E.; Verhulst, B.; Dale, P. S.; St Pourcain, B.
10.1101/2020.08.14.251199 — genetics — Posted on 2020-08-26
818 Curvilinear features are important for animate/inaimate categorization in macaques
Yetter, M.; Robert, S.; Mammarella, G.; Richmond, B.; Eldridge, M. A. G.; Ungerleider, L. G.; Yue, X.
10.1101/2020.08.25.267393 — neuroscience — Posted on 2020-08-26
823 Collegiate athlete brain data for white matter mapping and network neuroscience
Caron, B.; Stuck, R.; McPherson, B.; Bullock, D.; Kitchell, L.; Faskowitz, J.; Kellar, D.; Cheng, H.; Newman, S.; Port, N.; Pestilli, F.
10.1101/2020.08.25.267005 — neuroscience — Posted on 2020-08-26
827 Mutualistic interaction with Trichoderma longibrachiatum UENF-F476 boosted plant growth-promotion of Serratia marcescens UENF-22GI
Reis, R. J. A.; Alves, A. F.; Santos, P. H. D.; Aguiar, K. P.; Silveira, S. F.; Canellas, L. P.; Olivares, F. L.
10.1101/2020.08.24.265587 — microbiology — Posted on 2020-08-26
828 Longitudinal changes in brain metabolites in healthy subjects and patients with first episode psychosis (FEP): a 7-Tesla MRS study
Wang, M.; Barker, P. B.; Cascella, N.; Coughlin, J. M.; Nestadt, G.; Nucifora, F. C.; Sedlak, T. W.; Kelly, A.; Younes, L.; Geman, D.; Sawa, A.; Yang, K.
10.1101/2020.08.25.267419 — neuroscience — Posted on 2020-08-26
830 Non-invasive brain perfusion MRI using endogenous deoxyhemoglobin as a contrast agent: preliminary data
Poublanc, J.; Sobczyk, O.; Shafi, R.; Uludag, K.; Wood, J.; Vu, C.; Dharmakumar, R.; Fisher, J. A.; Mikulis, D. J.
10.1101/2020.08.21.255802 — neuroscience — Posted on 2020-08-26
831 Genome-wide haplotype association study in imaging genetics using whole-brain sulcal openings of 16,304 UK Biobank subjects.
Karkar, S. I.; Dandine-Roulland, C. I.; Mangin, J.-F.; Le Guen, Y.; Philippe, C.; Deleuze, J.-F.; Pierre-Jean, M.; Le Floch, E.; Frouin, V.
10.1101/2020.08.26.267617 — bioinformatics — Posted on 2020-08-26
833 Single-nucleus and spatial transcriptomics of archival pancreatic cancer reveals multi-compartment reprogramming after neoadjuvant treatment
Hwang, W. L.; Jagadeesh, K. A.; Guo, J. A.; Hoffman, H. I.; Yadollahpour, P.; Mohan, R.; Drokhlyansky, E.; Van Wittenberghe, N.; Ashenberg, O.; Farhi, S.; Schapiro, D.; Reeves, J. W.; Zollinger, D. R.; Eng, G.; Schenkel, J. M.; Freed-Pastor, W. A.; Rodrigues, C.; Gould, J.; Lambden, C.; Porter, C.; Tsankov, A.; Dionne, D.; Abbondanza, D.; Waldman, J.; Cuoco, M. S.; Nguyen, L.; Delorey, T.; Phillips, D.; Ciprani, D.; Kern, M.; Mehta, A.; Fuhrman, K.; Fropf, R.; Beechem, J. M.; Loeffler, J. S.; Ryan, D. P.; Weekes, C. D.; Ting, D. T.; Ferrone, C. R.; Wo, J. Y.; Hong, T. S.; Aguirre, A. J.; Rozen
10.1101/2020.08.25.267336 — genomics — Posted on 2020-08-25
838 Beyond brain age: Empirically-derived proxy measures of mental health
Dadi, K.; Varoquaux, G.; Houenou, J.; Bzdok, D.; Thirion, B.; Engemann, D. A.
10.1101/2020.08.25.266536 — neuroscience — Posted on 2020-08-25
842 Global FAW population genomic signature supports complex introduction events across the Old World
Tay, W. T.; Rane, R.; Padovan, A.; Walsh, T.; Elfekih, S.; Downes, S.; Nam, K.; d'Alencon, E.; Zhang, J.; Wu, Y.; Negre, N.; Kunz, D.; Kriticos, D. J.; Czepak, C.; Otim, M. H.; Gordon, K. H.
10.1101/2020.06.12.147660 — evolutionary biology — Posted on 2020-08-25
847 Roles of lysosomotropic agents on LRRK2 activation and Rab10 phosphorylation
Kuwahara, T.; Funakawa, K.; Komori, T.; Sakurai, M.; Yoshii, G.; Eguchi, T.; Fukuda, M.; Iwatsubo, T.
10.1101/2020.08.25.267385 — molecular biology — Posted on 2020-08-25
848 Ferrets not infected by SARS-CoV-2 in a high-exposure domestic setting
Sawatzki, K.; Hill, N. J.; Puryear, W. B.; Foss, A. D.; Stone, J. J.; Runstadler, J. A.
10.1101/2020.08.21.254995 — molecular biology — Posted on 2020-08-25
849 Titrating synapse number to treat MDD in Fragile X Syndrome
Heaney, C. F.; Namjoshi, S. V.; Uneri, A.; Bach, E. C.; Weiner, J. L.; Raab-Graham, K. F.
10.1101/2020.08.25.266833 — molecular biology — Posted on 2020-08-25
853 Potentially zoonotic gastrointestinal nematodes co-infecting free ranging non-human primates in Kenyan urban centres
Mbuthia, P.; Murungi, E.; Owino, V.; Akinyi, M.; Eastwood, G.; Nyamota, R.; Lekolool, I.; Jeneby, M.
10.1101/2020.08.19.254714 — zoology — Posted on 2020-08-25
856 PFRED: A computational platform for siRNA and antisense oligonucleotides design.
Sciabola, S.; Xi, H.; Cruz, D.; Cao, Q.; Lawrence, C.; Zhang, T.; Rotstein, S.; Hughes, J. D.; Caffrey, D. R.; Stanton, R. V.
10.1101/2020.08.25.265983 — bioinformatics — Posted on 2020-08-25
857 Predicting drug sensitivity of cancer cells based on DNA methylation levels
Fleck, J.; Pontes de Miranda, S.; Baiao, F.; Macaira, P.; Piccolo, S. R.
10.1101/2020.08.25.266049 — bioinformatics — Posted on 2020-08-25
858 Versatile, Multivalent Nanobody Cocktails Efficiently Neutralize SARS-CoV-2
Xiang, Y.; Nambulli, S.; Xiao, Z.; Liu, H.; Sang, Z.; Duprex, W. P.; Schneidman-Duhovny, D.; Zhang, C.; Shi, Y.
10.1101/2020.08.24.264333 — bioengineering — Posted on 2020-08-25
860 RNA promotes the formation of spatial compartments in the nucleus
Quinodoz, S. A.; Bhat, P.; Ollikainen, N.; Jachowicz, J. W.; Banerjee, A. K.; Chovanec, P.; Blanco, M. R.; Chow, A.; Markaki, Y.; Plath, K.; Guttman, M.
10.1101/2020.08.25.267435 — genomics — Posted on 2020-08-25
866 Sag currents are a major contributor to human pyramidal cell intrinsic differences across cortical layers
Moradi Chameh, H.; Rich, S.; Wang, L.; Chen, F.-D.; Zhang, L.; Carlen, P. L.; Tripathy, S.; Valiante, T. A.
10.1101/748988 — neuroscience — Posted on 2020-08-25
867 Power and coherence in the EEG of the rat: impact of behavioral states, cortical area, lateralization and light/dark phases
Mondino, A.; Cavelli, M.; Gonzalez, J.; Osorio, L.; Castro-Zaballa, S.; Costa, A.; Vanini, G.; Torterolo, P.
10.1101/2020.08.25.265520 — neuroscience — Posted on 2020-08-25
868 Dissociation between catecholamines and acetylcholine in the human cerebral cortex
Pfeffer, T.; Ponce-Alvarez, A.; Meindertsma, T.; Gahnstrom, C.; van den Brink, R. L.; Nolte, G.; Tsetsos, K.; Engel, A. K.; Deco, G.; Donner, T. H.
10.1101/2020.06.25.171199 — neuroscience — Posted on 2020-08-25
870 Spontaneous Axonal ER Ca2+ Waves Mediate a Shift From Action Potential-Dependent to Independent Glutamate Release in the YAC128 HD-Model
Mackay, J. P.; Smith-Dijak, A. I.; Koch, E. T.; Zhang, P.; Fung, E.; Nassrallah, W. B.; Buren, C.; Schmidt, M.; Hayden, M. R.; Raymond, L. A.
10.1101/2020.01.31.929299 — neuroscience — Posted on 2020-08-25
874 The S1/S2 boundary of SARS-CoV-2 spike protein modulates cell entry pathways and transmission
Zhu, Y.; Feng, F.; Hu, G.; Wang, Y.; Yu, Y.; Zhu, Y.; Xu, W.; Cai, X.; Sun, Z.; Han, W.; Ye, R.; Chen, H.; Ding, Q.; Cai, Q.; Qu, D.; Xie, Y.; Yuan, Z.; Zhang, R.
10.1101/2020.08.25.266775 — microbiology — Posted on 2020-08-25
875 Stellate cell computational modelling predicts signal filtering in the molecular layer circuit of cerebellum
Rizza, M. F.; Locatelli, F.; Masoli, S.; Sanchez-Ponce, D.; Munoz, A.; Prestori, F.; D'Angelo, E.
10.1101/2020.08.25.266429 — neuroscience — Posted on 2020-08-25
876 Medial prefrontal activity at encoding determines recognition of threatening faces after 1.5 years
Liu, X.; Zhou, X.; Zeng, Y.; Li, J.; Zhao, W.; Xu, L.; Zheng, X.; Fu, M.; Yao, S.; Cannistraci, C. V.; Kendrick, K. M.; Becker, B.
10.1101/2020.08.25.266353 — neuroscience — Posted on 2020-08-25
878 Confocal Laser-Scanning Fluorescence-Lifetime Single-Molecule Localisation Microscopy
Thiele, J. C.; Helmerich, D.; Oleksiievets, N.; Tsukanov, R.; Butkevich, E.; Sauer, M.; Nevskyi, O.; Enderlein, J.
10.1101/2020.08.25.266387 — biophysics — Posted on 2020-08-25
879 Unique mutational changes in SARS-CoV2 genome of different state of India
Prasad, P.; Prakash, S.; Sahu, K.; Singh, B.; Shukla, S.; Mishra, H.; Khan, D. N.; Prakash, O.; Bhatt, M.; Barik, S.; Asif, M. H.; Sawant, S. V.; Jain, A.; Bag, S. K.
10.1101/2020.08.24.265827 — bioinformatics — Posted on 2020-08-25
881 Precision digital mapping of endogenous andinduced genomic DNA breaks by INDUCE-seq
Dobbs, F. M.; van Eijk, P.; Fellows, M. D.; Loiacono, L.; Nitsch, R.; Reed, S. H.
10.1101/2020.08.25.266239 — genomics — Posted on 2020-08-25
884 Facilitation and biodiversity jointly drive mutualistic networks
Losapio, G.; Norton Hasday, E.; Espadaler, X.; Germann, C.; Ortiz-Sanchez, F. J.; Pont, A. C.; Sommaggio, D.; Schöb, C.
10.1101/2020.08.25.266346 — ecology — Posted on 2020-08-25
891 Cell-line-specific network models of ER+ breast cancer identify PI3Kα inhibitor sensitivity factors and drug combinations
Gomez Tejeda Zanudo, J.; Mao, P.; Alcon, C.; Kowalski, K. J.; Johnson, G. N.; Xu, G.; Baselga, J.; Scaltriti, M.; Letai, A.; Montero, J.; Albert, R.; Wagle, N.
10.1101/2020.08.25.261370 — cancer biology — Posted on 2020-08-25
897 Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetes patients
Farup, J.; Just, J.; de Paoli, F.; Lin, L.; Jensen, J. B.; Billeskov, T.; Roman, I. S.; Comert, C.; Moeller, A. B.; Madaro, L.; Groppa, E.; Fred, R. G.; Kampmann, U.; Pedersen, S. B.; Bross, P.; Stevnsner, T.; Eldrup, N.; Pers, T. H.; Rossi, F. M. V.; Puri, P. L.; Jessen, N.
10.1101/2020.08.25.243907 — cell biology — Posted on 2020-08-25
898 Experimental infection of cattle with SARS-CoV-2
Ulrich, L.; Wernike, K.; Hoffmann, D.; Mettenleiter, T. C.; Beer, M.
10.1101/2020.08.25.254474 — microbiology — Posted on 2020-08-25
901 Identification of SARS-CoV-2 induced pathways reveal drug repurposing strategies
Han, N.; Hwang, W.; Tzelepis, K.; Schmerer, P.; Yankova, E.; MacMahon, M.; Lei, W.; Katritsis, N. M.; Liu, A.; Schuldt, A.; Harris, R.; Chapman, K.; McCaughan, F.; Weber, F.; Kouzarides, T.
10.1101/2020.08.24.265496 — pharmacology and toxicology — Posted on 2020-08-25
902 Transcriptional subtype-specific microenvironmental crosstalk and tumor cell plasticity in metastatic pancreatic cancer
Raghavan, S.; Winter, P. S.; Navia, A. W.; Williams, H. L.; DenAdel, A.; Kalekar, R. L.; Galvez-Reyes, J.; Lowder, K. E.; Mulugeta, N.; Raghavan, M. S.; Borah, A. A.; Vayrynen, S. A.; Dias Costa, A.; Ng, R. W. S.; Wang, J.; Reilly, E.; Ragon, D. Y.; Brais, L. K.; Jaeger, A. M.; Spurr, L. F.; Li, Y. Y.; Cherniack, A. D.; Wakiro, I.; Rotem, A.; Johnson, B. E.; McFarland, J. M.; Sicinska, E. T.; Jacks, T. E.; Clancy, T. E.; Perez, K.; Rubinson, D. A.; Ng, K.; Cleary, J. M.; Crawford, L.; Manalis, S. R.; Nowak, J. A.; Wolpin, B. M.; Hahn, W. C.; Aguirre, A. J.; Shalek, A. K.
10.1101/2020.08.25.256214 — cancer biology — Posted on 2020-08-25
903 Transport mechanism of class-3 P4 ATPase lipid flippases
Li, H.; Bai, L.; You, Q.; Jain, B. K.; Graham, T. R.; Kovach, A.
10.1101/2020.08.25.266742 — biochemistry — Posted on 2020-08-25
904 Phenotype prediction from genome-wide genotyping data: a crowdsourcing experiment
Naret, O.; Baranger, D.; Greshake Tzovaras, B.; Mohanty, S. P.; Salathe, M.; Fellay, J.
10.1101/2020.08.25.265900 — genomics — Posted on 2020-08-25
905 Genome-wide methylation prediction of biological age using reproducing kernel Hilbert spaces and Bayesian ridge regressions
Amiri Roudbar, M.; Momen, M.; Mousavi, S. F.; Salek Ardestani, S.; Brito Lopes, F.; Gianola, D.; Khatib, H.
10.1101/2020.08.25.266924 — genomics — Posted on 2020-08-25
908 SARS-CoV-2 infection of human iPSC-derived cardiac cells predicts novel cytopathic features in hearts of COVID-19 patients
Perez-Bermejo, J. A.; Kang, S. S.; Rockwood, S. J.; Simoneau, C. R.; Joy, D. A.; Ramadoss, G. N.; Silva, A. C.; Flanigan, W. R.; Li, H.; Nakamura, K.; Whitman, J. D.; Ott, M.; Conklin, B. R.; McDevitt, T. C.
10.1101/2020.08.25.265561 — cell biology — Posted on 2020-08-25
911 Cis acting variation is common, can propagates across multiple regulatory layers, but is often buffered in developmental programs
Floc'hlay, S.; Wong, E.; Zhao, B.; Viales, R. R.; Thomas-Chollier, M.; Thieffry, D.; Garfield, D. A.; Furlong, E. E. M.
10.1101/2020.05.21.107961 — genomics — Posted on 2020-08-25
912 Bacterial single-cell genomics enables phylogenetic analysis of in vitro evolutionary studies
Bawn, M.; Hernandez, J.; Trampari, E.; Thilliez, G.; Webber, M. A.; Kingsley, R. A.; Hall, N.; Macaulay, I. C.
10.1101/2020.08.25.266213 — genomics — Posted on 2020-08-25
914 Group I p21-activated kinases in leukemia cell adhesion to fibronectin
Kuzelova, K.; Obr, A.; Roselova, P.; Grebenova, D.; Otevrelova, P.; Brodska, B.; Holoubek, A.
10.1101/2020.08.25.266056 — cell biology — Posted on 2020-08-25
916 Comprehensive annotation and characterization of planarian tRNA and tRNA-derived fragments (tRFs)
Lakshmanan, V.; Bansal, D.; T N, S.; Shivaprasad, P. V.; Palakodeti, D.; Gopinath, S. K.
10.1101/2020.08.25.266106 — molecular biology — Posted on 2020-08-25
917 Highly redundant neuropeptide volume cotransmission underlying episodic activation of the GnRH neuron dendron
Liu, X.; Yeo, S.-H.; McQuillan, H. J.; Herde, M. K.; Hessler, S.; Cheong, I.; Porteous, R.; Herbison, A. E.
10.1101/2020.08.25.266080 — neuroscience — Posted on 2020-08-25
918 Soil nutrient availability alters tree carbon allocation dynamics during drought
Schonbeck, L.; Li, M.-H.; Lehmann, M.; Rigling, A.; Schaub, M.; Hoch, G.; Kahmen, A.; Gessler, A.
10.1101/2020.08.25.266205 — plant biology — Posted on 2020-08-25
919 Tumor-educated uncommitted hematopoietic stem cells promote a metastatic switch
Magidey-Klein, K.; Klever, K.; Cooper, T. J.; Normand, R.; Zhang, T.; Timaner, M.; Raviv, Z.; James, B.; Gazit, R.; Ronai, Z. A.; Shen-Orr, S. S.; Shaked, Y.
10.1101/2020.08.25.266189 — cancer biology — Posted on 2020-08-25
920 A physical theory of larval Drosophila behaviour
Loveless, J.; Garner, A.; Issa, A. R.; Webb, B.; Ohyama, T.; Alonso, C.
10.1101/2020.08.25.266163 — biophysics — Posted on 2020-08-25
921 Stochastic pausing at latent HIV-1 promoters generates transcriptional bursting
Tantale, K.; Garcia-Olivier, E.; L'Hostis, A.; Yang, Y.; Robert, M.-C.; Gostan, T.; Basu, M.; Kozulic-Pirher, A.; Andrau, J.-C.; Muller, F.; Basyuk, E.; Radulescu, O.; Bertrand, E.
10.1101/2020.08.25.265413 — systems biology — Posted on 2020-08-25
922 Mycena genomes resolve the evolution of fungal bioluminescence
Ke, H.-M.; Lee, H.-H.; Lin, C.-Y. I.; Liu, Y.-C.; Lu, M. R.; Hsieh, J.-W. A.; Chang, C.-C.; Wu, P.-H.; Lu, M. J.; Li, J.-Y.; Shang, G.; Lu, R. J.-H.; Nagy, L. G.; Chen, P.-Y.; Kao, H.-W.; Tsai, I. J.
10.1101/2020.05.06.079921 — genomics — Posted on 2020-08-25
923 Two Piwis with Ago-like functions silence somatic genes at the chromatin level
Drews, F.; Karunanithi, S.; Goetz, U.; Marker, S.; De Wijn, R.; Pirritano, M.; Rodriegues Viana, A.; Jung, M.; Gasparoni, G.; Schulz, M.; Simon, M.
10.1101/2020.08.24.263970 — genetics — Posted on 2020-08-25
927 Power and coherence in the EEG of the rat: impact of behavioral states, cortical area, lateralization and light/dark phases
Mondino, A.; Cavelli, M.; Gonzalez, J.; Osorio, L.; Castro-Zaballa, S.; Costa, A.; Vanini, G.; Torterolo, P.
10.1101/2020.08.25.265520 — neuroscience — Posted on 2020-08-25
930 On stability of Canonical Correlation Analysis and Partial Least Squares with application to brain-behavior associations
Helmer, M.; Warrington, S. D.; Mohammadi-Nejad, A.-R.; Ji, J. L.; Howell, A.; Rosand, B.; Anticevic, A.; Sotiropoulos, S. N.; Murray, J. D.
10.1101/2020.08.25.265546 — neuroscience — Posted on 2020-08-25
931 Dissociable Roles of Pallidal Neuron Subtypes in Regulating Motor Patterns
Cherian, S.; Cui, Q.; Pamukcu, A.; Chang, I. Y.; Berceau, B.; Xenias, H.; Higgs, M.; Rajamanickam, S.; Chen, Y.; Du, X.; Zhang, Y.; McMorrow, H.; Abecassis, Z.; Boca, S.; Justice, N.; Wilson, C.; Chan, C. S.
10.1101/2020.08.23.263053 — neuroscience — Posted on 2020-08-25
937 A Connectome-Based Approach to Assess Motor Outcome after Neonatal Arterial Ischemic Stroke
Al Harrach, M.; Pretzel, P.; Groeschel, S.; Dhollander, T.; Hertz-Pannier, L.; Lefevre, J.; Chabrier, S.; Dinomais, M.
10.1101/2020.08.24.265173 — bioengineering — Posted on 2020-08-25
950 Morphometric reconstructions atlas shows insult-driven plasticity in cortical VIP/ChAT interneurons
Yayon, N.; Amsalem, O.; Dudai, A.; Yakov, O.; Adam, G.; Tessier-Lavigne, M.; Renier, N.; Segev, I.; London, M.; Soreq, H.
10.1101/2020.08.25.263178 — neuroscience — Posted on 2020-08-25
951 Multivariate associative patterns between the gut microbiota and large-scale brain network connectivity
Kohn, N.; Szopinska-Tokov, J.; Llera Arenas, A.; Beckmann, C. F.; Arias-Vasquez, A.; Aarts, E.
10.1101/2020.08.25.266122 — neuroscience — Posted on 2020-08-25
953 Susceptibility rhythm to bacterial endotoxin in myeloid clock-knockout mice
Lang, V.; Ferencik, S.; Ananthasubramaniam, B.; Kramer, A.; Maier, B.
10.1101/766519 — immunology — Posted on 2020-08-25
954 Neural crest-derived neurons are replaced by a newly identified mesodermal lineage in the post-natal and aging enteric nervous system
Kulkarni, S.; Saha, M.; Becker, L. S.; Wang, Z.; Liu, G.; Leser, J.; Kumar, M.; Bakhshi, S.; Anderson, M. J.; Lewandoski, M.; Slosberg, J.; Nagaraj, S.; Vincent, E.; Goff, L.; Pasricha, P. J.
10.1101/2020.08.25.262832 — neuroscience — Posted on 2020-08-25
955 Cdc42 activity is essential for the interplay between cAMP/PKA pathway and CatSper function
Luque, G. M.; Xu, X.; Romarowski, A.; Gervasi, M. G.; Orta, G.; De la Vega-Beltran, J.; Stival, C.; Gilio, N.; Dalotto-Moreno, T.; Krapf, D.; Visconti, P. E.; Krapf, D.; Darszon, A.; Buffone, M. G.
10.1101/2020.08.24.264739 — cell biology — Posted on 2020-08-25
956 Intracellular Staphylococcus aureus perturbs the host cell Ca2+-homeostasis to promote cell death
Stelzner, K.; Winkler, A.-C.; Chunguang, L.; Ade, C. P.; Dandekar, T.; Fraunholz, M.; Rudel, T.
10.1101/2020.08.20.260471 — microbiology — Posted on 2020-08-25
957 A distinct fingerprint of inflammatory mediators and miRNAs in Plasmodium vivax severe thrombocytopenia
Santos, M. L. S.; Coimbra, R. S.; Sousa, T. N.; Guimaraes, L. F. F.; Gomes, M. S.; Amaral, L. R.; Pereira, D.; Fontes, C. J. F.; Hawwari, I.; Franklin, B. S.; Carvalho, L. H.
10.1101/2020.08.20.260463 — microbiology — Posted on 2020-08-25
958 Preexisting memory CD4 T cells in naïve individuals confer robust immunity upon vaccination
Elias, G.; Meysman, P.; Bartholomeus, E.; De Neuter, N.; Keersmaekers, N.; Suls, A.; Jansens, H.; Souquette, A.; De Reu, H.; Smits, E.; Lion, E.; Thomas, P. G.; Mortier, G.; Van Damme, P.; Beutels, P.; Laukens, K.; Van Tendeloo, V.; Ogunjimi, B.
10.1101/2020.08.22.262568 — immunology — Posted on 2020-08-25
961 Dipeptidyl peptidase 9 triggers BRCA2 degradation by the N-degron pathway to promote DNA-damage repair
Silva-Garcia, M.; Bolgi, O.; Ross, B.; Pilla, E.; Vijayalakshmi, K.; Killisch, M.; Stark, N.; Lenz, C.; Spitzner, M.; Gorrell, M. D.; Grade, M.; Urlaub, H.; Dobbelstein, M.; Huber, R.; Geiss-Friedlander, R.
10.1101/2020.08.24.265033 — biochemistry — Posted on 2020-08-25
963 Identification and characterization of distinct murine brown adipocyte lineages
Ussar, S.; Karlina, R.; Lutter, D.; Miok, V.; Fischer, D. S.; Altun, I.; Schoettl, T.; Schorpp, K.; Israel, A.; Cero, C.; Johnson, J. W.; Kapser-Fischer, I.; Boettcher, A.; Keipert, S.; Feuchtinger, A.; Graf, E.; Strom, T. M.; Walch, A.; Lickert, H.; Walzthoeni, T.; Heinig, M.; Theis, F. J.; Garcia-Caceres, C.; Cypess, A. M.
10.1101/2020.08.24.264416 — cell biology — Posted on 2020-08-25
965 Single-cell mapper (scMappR): using scRNA-seq to infer cell-type specificities of differentially expressed genes
Sokolowski, D. J.; Faykoo-Martinez, M.; Erdman, L.; Hou, H.; Chan, C.; Zhu, H.; Holmes, M. M.; Goldenberg, A.; Wilson, M. D.
10.1101/2020.08.24.265298 — bioinformatics — Posted on 2020-08-25
969 Early developmental asymmetries in cell lineage trees in living individuals
Fasching, L.; Jang, Y.; Tomasi, S.; Schreiner, J.; Tomasini, L.; Brady, M.; Bae, T.; Sarangi, V.; Vasmatzis, N.; Wang, Y.; Szekely, A.; Fernandez, T. V.; Leckman, J.; Abyzov, A.; Vaccarino, F. M.
10.1101/2020.08.24.265751 — genomics — Posted on 2020-08-25
971 Biological invasions alter environmental microbiomes: a meta-analysis
Malacrino, A.; Sadowski, V. A.; Martin, T. K.; Cavichiolli de Oliveira, N.; Brackett, I. J.; Feller, J. D.; Harris, K. J.; Combita Heredia, O.; Vescio, R.; Bennett, A. E.
10.1101/2020.06.17.157883 — ecology — Posted on 2020-08-25
972 Origin and evolutionary dynamics of multi-drug resistant and highly virulent community-associated methicillin-resistant Staphylococcus aureus ST772-SCCmec V lineage
Bakthavatchalam, Y. D.; Vasudevan, K.; Rao, S. V.; Varughese, S.; Rupali, P.; Gina, M.; Zervos, M. J.; Peter, J. V.; Veeraraghavan, B.
10.1101/2020.08.24.265801 — microbiology — Posted on 2020-08-25
973 Molecular Characterization of Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates from Egyptian Patients
Hassan, R. M.; Salem, S. T.; Hassan, S. I. M.; Hegab, A. S.; Elkholy, Y. S.; Reem M Hassan, Sherifa T Salem, Saly Ismail Mostafa Hassan, Yasmine S Elkholy,
10.1101/2020.08.24.264911 — microbiology — Posted on 2020-08-25
979 MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions
Backx, E.; Wauters, E.; Baldan, J.; Van Bulck, M.; Michiels, E.; Heremans, Y.; De Paep, D. L.; Bouwens, L.; Goyama, S.; Kurokawa, M.; Jacquemin, P.; Houbracken, I.; Rooman, I.
10.1101/2020.08.21.260539 — cancer biology — Posted on 2020-08-24
980 St. Jude Cloud a Pediatric Cancer Genomic Data Sharing Ecosystem
McLeod, C.; Gout, A. M.; Zhou, X.; Rahbarinia, D.; Thrasher, A.; Newman, S.; Birch, K.; Macias, M.; Finkelstein, D.; Sunny, J.; Mudunuri, R.; Orr, B. A.; Treadway, M.; Davidson, B.; Ard, T.; Swistak, A.; Wiggins, S.; Foy, S.; Brady, S. W.; Wang, J.; Sioson, E.; Wang, S.; Michael, J. R.; Liu, Y.; Ma, X.; Patel, A.; Edmonson, M. N.; Wilkinson, M. R.; Frantz, A.; Chang, T.-C.; Tian, L.; Lei, S.; Meyer, C.; Thangaraj, N.; Tater, P.; Kandali, V.; Ma, S.; Nguyen, T.; Serang, O.; McGuire, I.; Thangaraj, N.; Gentry, D.; Tang, X.; Palmer, L.; Wu, G.; Suh, E.; Tanner, L.; McMurray, J.; Lear, M.; Wang, Z
10.1101/2020.08.24.264614 — cancer biology — Posted on 2020-08-24
981 An in vitro tumorigenesis model based on live cell-generated oxygen and nutrient gradients
Gilmore, A. C.; Flaherty, S. J.; Somasundaram, V.; Scheiblin, D. A.; Lockett, S. J.; Wink, D. A.; Heinz, W. F.
10.1101/2020.08.24.264580 — cancer biology — Posted on 2020-08-25
983 Learning epistatic gene interactions from perturbation screens
Elmes, K.; Schmich, F.; Szczurek, E.; Jenkins, J.; Beerenwinkel, N.; Gavryushkin, A.
10.1101/2020.08.24.264713 — bioinformatics — Posted on 2020-08-25
986 Large vs small genomes in Passiflora: the influence of the mobilome and the satellitome
Sader, M. A.; Vaio, M.; Cauz-Santos, L. A.; Dornelas, M.; Vieira, M. L.; Melo, N.; Pedrosa-Harand, A.
10.1101/2020.08.24.264986 — evolutionary biology — Posted on 2020-08-24
987 Contrasting signatures of introgression in North American box turtle (Terrapene spp.) contact zones
Martin, B. T.; Douglas, M. R.; Chafin, T. K.; Placyk, J. S.; Birkhead, R. D.; Phillips, C. A.; Douglas, M. E.
10.1101/752196 — evolutionary biology — Posted on 2020-08-25
988 Estimating encounter location distributions from animal tracking data
Noonan, M. J.; Martinez-Garcia, R.; Davis, G. H.; Crofoot, M. C.; Kays, R.; Hirsch, B. T.; Payne, E.; Sih, A.; Sinn, D. L.; Spiegel, O.; Fagan, W. F.; Fleming, C. H.; Calabrese, J.
10.1101/2020.08.24.261628 — ecology — Posted on 2020-08-25
989 An essential amino acid synchronises malaria parasite development with daily host rhythms
Prior, K. F.; Middleton, B.; Owolabi, A. T.; Westwood, M. L.; Holland, J.; O'Donnell, A. J.; Blackman, M. J.; Skene, D. J.; Reece, S. E.
10.1101/2020.08.24.264689 — microbiology — Posted on 2020-08-24
990 BlueFeather, the singleton that wasn't: Shared gene content analysis supports expansion of Arthrobacter phage cluster FE
Demo, S.; Kapinos, A.; Bernardino, A.; Guardino, K.; Hobbs, B.; Hoh, K.; Lee, E.; Vuong, I.; Reddi, K.; Freise, A. C.; Moberg Parker, J.
10.1101/2020.08.15.252577 — microbiology — Posted on 2020-08-24
992 The putative phosphate transporter PitB (PP1373) is involved in tellurite uptake in Pseudomonas putida KT2440
Montenegro, R.; Vieto, S.; Wicki-Emmenegger, D.; Vasquez-Castro, F.; Coronado-Ruiz, C.; Fuentes-Schweizer, P.; Calderon, P.; Pereira, R.; Chavarria, M.
10.1101/2020.08.24.265637 — microbiology — Posted on 2020-08-25
995 Minimal system for assembly of SARS-CoV-2 virus like particles
Swann, H.; Sharma, A.; Preece, B.; Peterson, A.; Eldredge, C.; Belnap, D.; Vershinin, M.; Saffarian, S.
10.1101/2020.06.01.128058 — biophysics — Posted on 2020-08-24
1002 The recombination landscape and multiple QTL mapping in a Solanum tuberosum cv. 'Atlantic'-derived F1 population
Da Silva Pereira, G.; Mollinari, M.; Schumann, M. J.; Clough, M. E.; Zeng, Z.-B.; Yencho, C.
10.1101/2020.08.24.265397 — genetics — Posted on 2020-08-24
1004 Divergent thermal challenges elicit convergent stress signatures in aposymbiotic Astrangia poculata
Wuitchik, D. M.; Almanzar, A.; Benson, B. E.; Brennan, S. A.; Chavez, J. D.; Liesegang, M. B.; Reavis, J. L.; Reyes, C. L.; Schniedewind, M. K.; Trumble, I. F.; Davies, S. W.
10.1101/2020.01.25.919399 — ecology — Posted on 2020-08-24
1005 Grazer behavior can regulate large-scale patterns of community states
Karatayev, V. A.; Baskett, M. L.; Kushner, D. J.; Shears, N. T.; Caselle, J. E.; Boettiger, C.
10.1101/722215 — ecology — Posted on 2020-08-24
1006 An optogenetic method for interrogating YAP1 and TAZ nuclear-cytoplasmic shuttling
Dowbaj, A. M.; Jenkins, R. P.; Heddleston, J. M.; Ciccarelli, A.; Fallesen, T.; Hahn, K.; Montagner, M.; Sahai, E. M.
10.1101/2020.06.08.140228 — cell biology — Posted on 2020-08-24
1010 Identification of an N-acetylneuraminic acid-presenting bacteria isolated from a healthy human microbiome
Han, Z.; Thuy-Boun, P. S.; Pfeiffer, W.; Vartabedian, V. F.; Torkamani, A.; Teijaro, J. R.; Wolan, D. W.
10.1101/2020.08.24.265504 — microbiology — Posted on 2020-08-24
1014 Stool methanogens in intestine mammal species.
GUINDO, C. O.; Davoust, B.; Drancourt, M.; Grine, G.
10.1101/2020.08.24.264788 — microbiology — Posted on 2020-08-24
1015 Faster Cryptococcus melanization increases virulence in experimental and human cryptococcosis
Sousa, H. R. d.; Oliveira, G. P. d.; Frazao, S. d. O.; Gorgonha, K. C. d. M.; Rosa, C. P.; Garcez, E. M.; Lucas, J.; Correia, A. F.; Freitas, W. F. d.; Borges, H. M.; Paes, H. C.; Trilles, L.; Lazera, M. d. S.; Pinto, V. L.; Felipe, M. S. S.; Casadevall, A.; Silva-Pereira, I.; Albuquerque, P.; Nicola, A. M.
10.1101/2020.07.29.222794 — microbiology — Posted on 2020-08-24
1016 Profiles of Expression pattern and tissue distribution of host defense peptides genes in different chicken (Gallus gallus) breeds related to body weight
Li, Z.; Ahmed, I.; Xu, Z.; Sun, S.; Li, T.; Gu, D.; Li, Y.; Zhang, X.; Yan, S.; Hu, W.; Jiang, Z.; Duan, X.; Li, Q.; Liu, L.; Rong, H.; Wang, K.; Abdulwahid, A. M.; Dou, T.; Wang, S.; Su, Z.; Ge, C.; te Pas, M. F. W.; Jia, J.; Huang, Y.
10.1101/2020.08.24.264861 — immunology — Posted on 2020-08-24
1017 Enrichment of disease-associated genes in cortical areas defined by transcriptome-based parcellation
Gryglewski, G.; Murgas, M.; Michenthaler, P.; Kloebl, M.; Reed, M. B.; Unterholzner, J.; Lanzenberger, R.
10.1101/2020.03.02.971911 — neuroscience — Posted on 2020-08-24
1018 A non-human primate model of familial Alzheimer's disease
Sato, K.; Sasaguri, H.; Kumita, W.; Inoue, T.; Kurosaki, Y.; Nagata, K.; Mihira, N.; Sato, K.; Sakuma, T.; Yamamoto, T.; Tagami, M.; Manabe, R.-i.; Ozaki, K.; Okazaki, Y.; Saido, T. C.; Sasaki, E.
10.1101/2020.08.24.264259 — neuroscience — Posted on 2020-08-24
1019 Circuit reorganization in the Drosophila mushroom body calyx accompanies memory consolidation
Baltruschat, L. G.; Ranft, P.; Prisco, L.; Lauritzen, J. S.; Fiala, A.; Bock, D.; Tavosanis, G.
10.1101/2020.08.20.259135 — neuroscience — Posted on 2020-08-24
1021 Assessing Study Reproducibility through MMRI: A Novel Approach for Large-scale High-throughput Association Studies
Jiao, Z.; Lai, Y.; Kang, J.; Gong, W.; Ma, L.; Jia, T.; Xie, C.; Cheng, W.; Heinz, A.; Desrivieres, S.; Schumann, G.; Sun, F.; Feng, J.
10.1101/2020.08.18.253740 — neuroscience — Posted on 2020-08-24
1024 A functional chromogen gene C from wild rice is involved in a different anthocyanin biosynthesis pathway in indica and japonica
Qiao, W.; Wang, Y.; Xu, R.; Yang, Z.; Sun, Y.; Su, L.; Zhang, L.; Wang, J.; Huang, J.; Zheng, X.; Liu, S.; Tian, Y.; Chen, L.; Liu, X.; Lan, J.; Yang, Q.
10.1101/2020.08.24.264770 — plant biology — Posted on 2020-08-24
1026 Enhancing c-MYC degradation via 20S proteasome activation induces in vivo anti-tumor efficacy
Njomen, E.; Lansdell, T.; Vanecek, A.; Benham, V.; Bernard, M.; Yang, Y.-T.; Schall, P.; Isaac, D.; Alkharabsheh, O.; Al-Janadi, A.; Giletto, m.; Elsworth, E.; Taylor, C.; Yang, T.; Bailie, m.; Bernard, J.; Yuzbasiyan-Gurkan, V.; Tepe, J.
10.1101/2020.08.24.265470 — pharmacology and toxicology — Posted on 2020-08-24
1028 Cell state diversity promotes metastasis through heterotypic cluster formation in melanoma
Campbell, N. R.; Rao, A.; Zhang, X.; Baron, M.; Heilmann, S.; Deforet, M.; Kenny, C.; Ferretti, L.; Huang, T.-H.; Garg, M.; Nsengimana, J.; Montal, E.; Tagore, M.; Hunter, M.; Newton-Bishop, J.; Middleton, M.; Corrie, P.; Adams, D.; Rabbie, R.; Levesque, M.; Cornell, R.; Yanai, I.; Xavier, J.; White, R.
10.1101/2020.08.24.265140 — cancer biology — Posted on 2020-08-24
1032 Versatile, Multivalent Nanobody Cocktails Efficiently Neutralize SARS-CoV-2
Shi, Y.; Schneidman-Duhovny, D.; Xiang, Y.; Zhang, C.; Sang, Z.; Duprex, P.; Xiao, Z.; Nambulli, S.; Liu, H.
10.1101/2020.08.24.264333 — bioengineering — Posted on 2020-08-24
1033 Water requirement and growth indicators of forest tree species seedlings produced with automated irrigation management
Bueno, M. M.; dos Santos Leles, P. S.; Goncalves Abreu, J. F.; dos Santos, J. J. S.; de Carvalho, D. F.
10.1101/2020.08.24.264879 — bioengineering — Posted on 2020-08-24
1034 IMMUNE SYSTEM CHALLENGE IMPROVES COGNITIVE-BEHAVIOURAL RESPONSES AND REVERSES MALARIA-INDUCED COGNITIVE IMPAIRMENT IN MICE
de Sousa Vieira, L. P.; Ribeiro-Gomes, F. L.; Almeida, R. F.; e Souza, T. M.; Werneck, G.; Souza, D. O.; Daniel-Ribeiro, C. T.
10.1101/2019.12.13.874420 — animal behavior and cognition — Posted on 2020-08-24
1037 Tissue-specific transcription footprinting using RNA PoI DamID (RAPID) in C. elegans
Gomez-Saldivar, G.; Osuna-Luque, J.; Glauser, D. A.; Jarriault, S.; Meister, P.
10.1101/2020.08.19.257873 — genetics — Posted on 2020-08-24
1038 Trade-offs of managing Arctic predator harvest instability in fluctuating oceans
Goto, D.; Filin, A. A.; Howell, D.; Bogstad, B.; Kovalev, Y.; Gjosaeter, H.
10.1101/2020.06.17.154971 — ecology — Posted on 2020-08-24
1040 The 3UTR of the orb2 gene encoding the Drosophila CPEB translation factor plays a critical role in spermatogenesis
Gilmutdinov, R. A.; Kozlov, E. N.; Olenina, L. V.; Kotov, A. A.; Barr, J.; Zhukova, M. V.; Schedl, P.; Shidlovskii, Y.
10.1101/2020.08.24.264762 — developmental biology — Posted on 2020-08-24
1041 FUS-dependent liquid-liquid phase separation is an early event in double-strand break repair
Levone, B. R.; Lenzken, S. C.; Antonaci, M.; Maiser, A.; Rapp, A.; Conte, F.; Reber, S.; Ronchi, A. E.; Muhlemann, O.; Leonhardt, H.; Cristina Cardoso, M.; Ruepp, M.-D.; Barabino, S. M. L.
10.1101/798884 — molecular biology — Posted on 2020-08-24
1043 From the Andes to the desert: First characterization of bacterial communities in the Rimac river, the main source of water for Lima, Peru
Romero, P. E.; Calla-Quispe, E.; Castillo-Vilcahuaman, C.; Yokoo, M.; Lino Fuentes-Rivera, H.; Ramirez, J. L.; Ibanez, A. J.; Wong, P.
10.1101/2020.08.16.252965 — microbiology — Posted on 2020-08-24
1044 An evolutionarily conserved Lhx2-Ldb1 interaction regulates the acquisition of hippocampal cell fate and regional identity
Kinare, V.; Iyer, A.; Padmanabhan, H.; Godbole, G.; Khan, T.; Khatri, Z.; Maheshwari, U.; Muralidharan, B.; Tole, S.
10.1101/2020.08.24.265207 — neuroscience — Posted on 2020-08-24
1046 Standardizing Human Brain Parcellations
Lawrence, R. M.; Bridgeford, E. W.; Myers, P. E.; Arvapalli, G. C.; Ramachandran, S. C.; Pisner, D. A.; Frank, P. F.; Lemmer, A. D.; Nikolaidis, A.; Vogelstein, J. T.
10.1101/845065 — neuroscience — Posted on 2020-08-24
1047 The gut microbiome regulates memory function
Noble, E. E.; Olson, C.; Davis, E. A.; Tsan, L.; Chen, Y.-W.; Schade, R.; Liu, C.; Suarez, A. N.; Jones, R. B.; Goran, M. I.; de La Serre, C.; Yang, X.; Hsiao, E. Y.; Kanoski, S.
10.1101/2020.06.16.153809 — neuroscience — Posted on 2020-08-24
1048 Gamma rhythms and visual information in mouse V1 specifically modulated by somatostatin-positive neurons in reticular thalamus
Hoseini, M. S.; Higashikubo, B.; Cho, F. S.; Chang, A. H.; Clemente-Perez, A.; Lew, I.; Stryker, M. P.; Paz, J. T.
10.1101/2020.05.06.081877 — neuroscience — Posted on 2020-08-24
1050 Robust effects of corticothalamic feedback during naturalistic visual stimulation
Spacek, M. A.; Born, G.; Crombie, D.; Bauer, Y.; Liu, X.; Katzner, S.; Busse, L.
10.1101/776237 — neuroscience — Posted on 2020-08-24
1051 Methods for detecting PER2::LUCIFERASE bioluminescence rhythms in freely moving mice
Martin-Burgos, B.; Wang, W.; William, I.; Tir, S.; Mohammad, I.; Javed, R.; Smith, S.; Cui, Y.; Smith, C.; van der Vinne, V.; Molyneux, P. C.; Miller, S. C.; Weaver, D. R.; Leise, T. L.; Harrington, M.
10.1101/2020.08.24.264531 — systems biology — Posted on 2020-08-24
1052 Lamellar cells in Pacinian and Meissner corpuscles are touch sensors
Nikolaev, Y. A.; Feketa, V. V.; Anderson, E. O.; Gracheva, E. O.; Bagriantsev, S. N.
10.1101/2020.08.24.265231 — physiology — Posted on 2020-08-24
1053 Reconstructing the lineage histories and differentiation trajectories of individual cancer cells in JAK2-mutant myeloproliferative neoplasms
Van Egeren, D.; Escabi, J.; Nguyen, M.; Liu, S.; Reilly, C. R.; Patel, S.; Kamaz, B.; Kalyva, M.; DeAngelo, D. J.; Galinsky, I.; Wadleigh, M.; Winer, E. S.; Luskin, M. R.; Stone, R. M.; Garcia, J. S.; Hobbs, G. S.; Camargo, F. D.; Michor, F.; Mullally, A.; Cortes-Ciriano, I.; Hormoz, S.
10.1101/2020.08.24.265058 — cancer biology — Posted on 2020-08-24
1055 Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum
Cochet-Escartin, O.; Demircigil, M.; Hirose, S.; Allais, B.; Calvez, V.; Funamoto, K.; Anjard, C.; Rieu, J.-P.
10.1101/2020.08.17.246082 — biophysics — Posted on 2020-08-24
1056 EPIP: MHC-I epitope prediction integrating mass spectrometry derived motifs and tissue-specific expression profiles
Hu, W.; Qiu, S.; Li, Y.; Lin, X.; Zhang, L.; Xiang, H.; Han, X.; Zhu, S.; Chen, L.; Li, S.; Li, W.; Ren, Z.; Hou, G.; Lin, Z.; Lu, J.; Liu, G.; Li, B.; Lee, L.
10.1101/567081 — bioinformatics — Posted on 2020-08-24
1058 Unsupervised content-preserving transformation for optical microscopy
Li, X.; Zhang, G.; Qiao, H.; Bao, F.; Deng, Y.; Wu, J.; He, Y.-F.; Yun, J.; Lin, X.; Xie, H.; Wang, H.; Dai, Q.
10.1101/848077 — bioinformatics — Posted on 2020-08-24
1061 Modeling Epistasis in Mice and Yeast Using the Proportion of Two or More Distinct Genetic Backgrounds: Evidence for "Polygenic Epistasis"
Rau, C. D.; Gonzales, N. M.; Bloom, J. S.; Park, D.; Ayroles, J. S.; Palmer, A. A.; Lusis, A. J.; Zaitlen, N.
10.1101/555383 — genomics — Posted on 2020-08-24
1062 Genome scale epigenomic analysis of response to acute stress in the European sea bass (Dicentrarchus labrax, L.)
KRICK, M. V.; DESMARAIS, E.; SAMARAS, A.; GUERET, E.; DIMITROGLOU, A.; PAVLIDIS, M.; TSIGENOPOULOS, C. S.; GUINAND, B.
10.1101/2020.06.19.160812 — genomics — Posted on 2020-08-24
1063 Genomic diversity generated by a transposable element burst in a rice recombinant inbred population
Chen, J.; Lu, L.; Robb, S. M. C.; Collin, M.; Okumoto, Y.; Stajich, J. E.; Wessler, S. R.
10.1101/2020.08.24.265538 — genetics — Posted on 2020-08-24
1065 b3galt6 knock-out zebrafish recapitulate β3GalT6-deficiency disorders in human and reveal a trisaccharide proteoglycan linkage region
Delbaere, S.; De Clercq, A.; Mizumoto, S.; Noborn, F.; Bek, J. W.; Alluyn, L.; Gistelinck, C.; Syx, D.; Salmon, P. L.; Coucke, P. J.; Larson, G.; shuhei, Y.; Willaert, A.; Malfait, F.
10.1101/2020.06.22.165316 — genetics — Posted on 2020-08-24
1069 Insect herbivory on urban trees: Complementary effects of tree neighbours and predation
Stemmelen, A.; Paquette, A.; Benot, M.-L.; Kadiri, Y.; Jactel, H.; Castagneyrol, B.
10.1101/2020.04.15.042317 — ecology — Posted on 2020-08-24
1071 Non-autonomous regulation of germline stem cell proliferation bysomatic MPK-1/MAPK activity in C. elegans
Robinson-Thiewes, S.; Dufour, B.; Martel, P.-O.; Lechasseur, X.; Danielle Brou, A. A.; Roy, V.; Chen, Y.; Kimble, J.; Narbonne, P.
10.1101/2020.08.24.265249 — developmental biology — Posted on 2020-08-24
1072 Ecology of inorganic sulfur auxiliary metabolism in widespread bacteriophages
Kieft, K.; Zhou, Z.; Anderson, R. E.; Buchan, A.; Campbell, B. J.; Hallam, S.; Hess, M.; Sullivan, M. B.; Walsh, D. A.; Roux, S.; Anantharaman, K.
10.1101/2020.08.24.253096 — microbiology — Posted on 2020-08-24
1073 Small RNA directs symbiosis, virulence, and natural products biosynthesis in entomopathogenic bacteria
Neubacher, N.; Tobias, N. J.; Huber, M.; Cai, X.; Glatter, T.; Pidot, S. J.; Stinear, T. P.; Luetticke, A. L.; Papenfort, K.; Bode, H. B.
10.1101/2020.08.24.265355 — microbiology — Posted on 2020-08-24
1075 Distinct cortical systems reinstate the content and context of episodic memories
Kragel, J. E.; Ezzyat, Y.; Lega, B. C.; Sperlin, M. R.; Worrell, G. A.; Gross, R. E.; Jobst, B. C.; Sheth, S. A.; Zaghloul, K. A.; Stein, J. M.; Kahana, M. J.
10.1101/2020.08.20.248567 — neuroscience — Posted on 2020-08-24
1078 Tumor genotype dictates radiosensitization after Atm deletion in brainstem gliomas
Deland, K.; Starr, B. F.; Mercer, J. S.; Byemerwa, J.; Crabtree, D. M.; Williams, N. T.; Luo, L.; Ma, Y.; Chen, M.; Becher, O. J.; Kirsch, D. G.
10.1101/2020.08.24.262642 — cancer biology — Posted on 2020-08-24
1079 Discovery and Development of Novel DNA-PK Inhibitors by Targeting the unique Ku-DNA Interaction
Gavande, N. S.; VanderVere-Carozza, P. S.; Pawelczak, K. S.; Vernon, T. L.; Hanakahi, L. A.; Summerlin, M.; Dynlacht, J. R.; Farmer, A. H.; Sears, C. R.; Al Nasrallah, N.; Garrett, J.; Turchi, J. J.
10.1101/2020.08.24.261875 — biochemistry — Posted on 2020-08-24
1082 Genome-Wide Mapping of Human DNA Replication by Optical Replication Mapping Supports a Stochastic Model of Eukaryotic Replication Timing
Wang, W.; Klein, K.; Proesmans, K.; Yang, H.; Marchal, C.; Zhu, X.; Borrman, T.; Hastie, A.; Weng, Z.; Bechhoefer, J.; Chen, C.-L.; Gilbert, D. M.; Rhind, N.
10.1101/2020.08.24.263459 — genomics — Posted on 2020-08-24
1084 Alpha-ketoglutarate inhibits Regulatory T cell differentiation by coupling lipidome remodelling to mitochondrial metabolism
Matias, M.; Yong, C. S.; Foroushani, A.; Sezgin, E.; Levental, K. R.; Talebi, A.; Mongellaz, C.; Dehair, J.; Wong, M.; Chavakis, T.; Kinet, S.; Zimmermann, V. S.; Levental, I.; Yvan-Charvet, L.; Swinnen, J. v.; Muljo, S.; Tardito, S.; Dardalhon, V.; Taylor, N.
10.1101/2020.08.24.256560 — immunology — Posted on 2020-08-24
1085 TOLLIP promotes durable alveolar macrophage-mediated immunity during Mycobacterium tuberculosis infection by resolving cellular stress from lipids.
Venkatasubramanian, S.; Plumlee, C.; Dill-McFarland, K.; Pearson, G.; Cohen, S. B.; Lietzke, A.; Pryor, R.; Soleimanpour, S. A.; Altman, M.; Urdahl, K. B.; Shah, J. A.
10.1101/2020.08.24.263624 — immunology — Posted on 2020-08-24
1086 Induction of SARS-CoV-2 protein S-specific CD8+ T cells in the lungs of gp96-Ig-S vaccinated mice
Fisher, E.; Padula, L.; Podack, K.; O'Neill, K.; Seavey, M. M.; Jayaraman, P.; Jasuja, R.; Strbo, N.
10.1101/2020.08.24.265090 — immunology — Posted on 2020-08-24
1088 Manipulation of striatal population dynamics using temperature warps judgment of time
Monteiro, T.; Rodrigues, F. S.; Pexirra, M.; Cruz, B. F. P.; Goncalves, A. I.; Rueda-Orozco, P. E.; Paton, J. J.
10.1101/2020.08.24.251827 — neuroscience — Posted on 2020-08-24
1093 SARS-CoV-2 neutralizing human antibodies protect against lower respiratory tract disease in a hamster model
Haagmans, B. L.; Noack, D.; Okba, N. M. A.; LI, W.; Wang, C.; Bestebroer, T.; de Vries, R.; Herfst, S.; de Meulder, D.; van Run, P.; Lamers, M. M.; Rijnders, B.; Rokx, C.; van Kuppeveld, F. J. M.; Grosveld, F.; Drabek, D.; GeurtsvanKessel, C.; Koopmans, M.; Bosch, B. J.; Kuiken, T.; Rockx, B.
10.1101/2020.08.24.264630 — microbiology — Posted on 2020-08-24
1094 A simple protein-based surrogate neutralization assay for SARS-CoV-2
Abe, K. T.; Li, Z.; Samson, R.; Samavarchi-Tehrani, P.; Valcourt, E. J.; Wood, H.; Budylowski, P.; Dupuis, A. P.; Girardin, R. C.; Rathod, B.; Colwill, K.; McGeer, A. J.; Mubareka, S.; Gommerman, J. L.; Durocher, Y.; Ostrowski, M.; McDonough, K. A.; Drebot, M. A.; Drews, S. J.; Rini, J. M.; Gingras, A.-C.
10.1101/2020.07.10.197913 — immunology — Posted on 2020-08-24
1095 SARS-CoV-2 Spike protein hijacks VEGF-A/Neuropilin-1 receptor signaling to induce analgesia
Moutal, A.; Martin, L. F.; Boinon, L.; Gomez, K.; Ran, D.; Zhou, Y.; Stratton, H. J.; Song, C.; Luo, S.; Gonzalez, K. B.; Perez-Miller, S.; Patwardhan, A.; Ibrahim, M.; Khanna, R.
10.1101/2020.07.17.209288 — neuroscience — Posted on 2020-08-24
1097 An hACE2 peptide mimic blocks SARS-CoV-2 Pulmonary Cell Infection
Karoyan, P.; Vieillard, V.; Odile, E.; Denis, A.; Gomes-Morales, L.; Grondin, P.; Lequin, O.
10.1101/2020.08.24.264077 — pharmacology and toxicology — Posted on 2020-08-24
1098 Acquired deficiency of the peroxisomal enzyme enoyl-CoA hydratase/3-hydroxyacyl CoA dehydrogenase is a metabolic vulnerability in hepatoblastoma
Wang, H.; Chen, X.; Schwalbe, M.; Gorka, J. E.; Mandel, J. A.; Wang, J.; Lu, J.; Goetzman, E. S.; Dobrowolski, S.; Prochownik, E. V.
10.1101/2020.08.24.265421 — cancer biology — Posted on 2020-08-24
1099 MTOR promotes basal cell carcinoma growth through atypical PKC
Chow, R. Y.; Levee, T. M.; Kaur, G.; Cedeno, D. P.; Doan, L. T.; Atwood, S. X.
10.1101/2020.08.24.264598 — cancer biology — Posted on 2020-08-24
1102 Mechanism and kinetics of copper complexes binding to the influenza A M2 channel
Busath, D. D.; McGuire, K. L.; Ess, D. H.; Smit, P.; Harrison, R. G.; Hill, J. T.
10.1101/2020.08.24.265165 — biophysics — Posted on 2020-08-24
1103 A negative feedback model to explain regulation of SARS-CoV-2 replication and transcription
Shan, G.; Zhi, C.; Xiufeng, J.; Fang, W.; Yibo, X.; Hao, Z.; Chang, L.; Jishou, R.; Guangyou, D.; Xin, L.
10.1101/2020.08.23.263327 — bioinformatics — Posted on 2020-08-24
1107 Discovery of drugs to treat cytokine storm-induced cardiac dysfunction using human cardiac organoids
Mills, R. J.; Humphrey, S. J.; Fortuna, P. R.; Quaife-Ryan, G. A.; Mehdiabadi, N. R.; Devilee, L.; Voges, H. K.; Reynolds, L. T.; Krumeich, S.; Mathieson, E.; Griffen, B.; Titmarsh, D. M.; Porrello, E. R.; Smyth, M. J.; Engwerda, C. R.; MacDonald, K. P.; Bald, T.; James, D. E.; Hudson, J. E.
10.1101/2020.08.23.258574 — cell biology — Posted on 2020-08-24
1108 Pathogenicity, immunogenicity, and protective ability of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein
Wang, P.; Lau, S.-Y.; Deng, S.; Chen, P.; Mok, B. W.-Y.; Zhang, A. J.; Lee, A. C.-Y.; Chan, K.-H.; Song, W.; To, K. K.-W.; Chen, J. F.-W.; Yuen, K.-Y.; Chen, H.
10.1101/2020.08.24.264192 — microbiology — Posted on 2020-08-24
1113 Deep learning-based molecular morphometrics for kidney biopsies
Zimmermann, M.; Klaus, M.; Wong, M. N.; Thebille, A.-K.; Gernhold, L.; Kuppe, C.; Halder, M.; Kranz, J.; Wanner, N.; Braun, F.; Wulf, S.; Wiech, T.; Panzer, U.; Krebs, C. F.; Hoxha, E.; Kramann, R.; Huber, T. B.; Bonn, S.; Puelles, V. G.
10.1101/2020.08.23.263392 — pathology — Posted on 2020-08-24
1117 Methylmalonic acid compromises mitochondrial respiration and reduces the expression of markers of differentiation in SH-SY5Y human neuroblastoma cells
Costa, R. T. d.; Santos, M. B. d.; Silva, I. C. S.; Almeida, R. P. d.; Teruel, M. S.; Carrettiero, D. C.; Ribeiro, C. A. J.
10.1101/2020.08.24.265157 — biochemistry — Posted on 2020-08-24
1119 The spatial landscape of gene expression isoforms in tissue sections
Lebrigand, K.; Bergenstrahle, J.; Thrane, K.; Mollbrink, A.; Barbry, P.; Waldmann, R.; Lundeberg, J.
10.1101/2020.08.24.252296 — genomics — Posted on 2020-08-24
1124 Mutation of IDR1 enhances drought tolerance by reducing ROS production and activating ROS scavenging in rice
Zu, X.; Lu, Y.; Wang, Q.; La, Y.; Tan, F.; Niu, J.; Xia, H.; Hong, X.; Wu, Y.; Zhou, S.; Li, K.; Chen, H.; Qiang, S.; Rui, Q.; Wang, H.; La, H.
10.1101/2020.08.24.264556 — plant biology — Posted on 2020-08-24
1125 Dataset of the construction and characterization of stable biological nanoparticles
Gisonno, R. A.; Tricerri, M. A.; Gonzalez, M. C.; Garda, H. A.; Ramella, N. A.; Diaz Ludovico, I.
10.1101/2020.08.23.263590 — biophysics — Posted on 2020-08-24
1130 Gradual evolution of allopolyploidy in Arabidopsis suecica
Burns, R.; Mandakova, T.; Jagoda, J.; Soto-Jimenez, L. M.; Liu, C.; Lysak, M. A.; Novikova, P. Y.; Nordborg, M.
10.1101/2020.08.24.264432 — evolutionary biology — Posted on 2020-08-24
1138 Biophysical characterization of the ETV6 PNT domain polymerization interfaces
Gerak, C. A. N.; Cho, S. Y.; Kolesnikov, M.; Okon, M.; Murphy, M. E. P.; Sessions, R. B.; Roberge, M.; McIntosh, L. P.
10.1101/2020.08.21.262121 — biochemistry — Posted on 2020-08-24
1139 Causal Understanding of the Stone Dropping Task in Two Species of Macaw
O'Neill, L.; Picaud, A.; Hastings, R.; Buffenoir, N.; Gahr, M.; von Bayern, A. M. P.
10.1101/2020.08.24.264390 — animal behavior and cognition — Posted on 2020-08-24
1144 Staphylococcus aureus small-colony variants exhibit genotype specific hyperinflammation
Tang, Q.; Precit, M.; Thomason, M.; Ahmed-Qadri, F.; McFarland, A.; Wolter, D.; Hoffman, L.; Woodward, J. J.
10.1101/2020.08.21.261750 — molecular biology — Posted on 2020-08-24
1145 Sustainable Production of Camptothecin from an Alternaria sp. isolated from Nothapodytes nimmoniana
Ismail Abdul Hameed, K. M.; Kanumuri, R.; K. N., S.; Ramanan, U. S.; Rayala, S. K.; Srivastava, S.
10.1101/2020.08.23.263129 — microbiology — Posted on 2020-08-24
1146 Dynamic hormone control of stress and fertility
Zavala, E.; Voliotis, M.; Zerenner, T.; Tabak, J.; Walker, J. J.; Li, X. F.; Terry, J. R.; Lightman, S. L.; O'Byrne, K.; Tsaneva-Atanasova, K.
10.1101/2020.08.24.264234 — systems biology — Posted on 2020-08-24
1147 Discovery of NOvel CIP2A VAriant (NOCIVA) and its clinical relevance in myeloid leukemias
Makela, E.; Pavic, K.; Varila, T.; Salmenniemi, U.; Loyttyniemi, E.; Nagelli, S.; Kahari, V.-M.; Clark, R. E.; Bachanaboyina, V. K.; Lucas, C.; Itala-Remes, M.; Westermarck, J.
10.1101/2020.08.24.264606 — cancer biology — Posted on 2020-08-24
1149 Disinfection chemicals mode of action on the bacterial spore structure and their Raman spectra
Malyshev, D.; Dahlberg, T.; Wiklund, K.; Andersson, P. O.; Henriksson, S.; Andersson, M.
10.1101/2020.08.24.264440 — biophysics — Posted on 2020-08-24
1150 EmpiReS: Differential Analysis of Gene Expression and Alternative Splicing
Csaba, G.; Berchtold, E.; Hadziahmetovic, A.; Gruber, M.; Ammar, C.; Zimmer, R.
10.1101/2020.08.23.234237 — bioinformatics — Posted on 2020-08-24
1152 Synthesis and Evaluation of a Stable Isostere of Malonyllysine
Bergholtz, S. E.; Jing, Y.; Kulkarni, R. A.; Zengeya, T. T.; Meier, J. L.
10.1101/2020.08.23.263285 — biochemistry — Posted on 2020-08-24
1153 Modular metabolite assembly in C. elegans lysosome-related organelles
Le, H. H.; Wrobel, C. J.; Cohen, S. M.; Yu, J.; Park, H.; Helf, M. J.; Curtis, B. J.; Rodrigues, P. R.; Sternberg, P. W.; Schroeder, F. C.
10.1101/2020.08.22.262956 — biochemistry — Posted on 2020-08-24
1155 Macrophages provide a transient muscle stem cell niche via NAMPT secretion
Ratnayake, D.; Nguyen, P. D.; Rossello, F. J.; Wimmer, V. C.; Isiaku, A. I.; Galvis, L. A.; Wood, A. J.; Julier, Z.; Boudier, T.; Oorschot, V.; Rogers, K. L.; Martino, M. M.; Marcelle, C.; Lieschke, G. J.; Bakkers, J.; Currie, P. D.
10.1101/2020.08.24.262428 — cell biology — Posted on 2020-08-24
1158 Dissociable Roles of Pallidal Neuron Subtypes in Regulating Motor Patterns
Cherian, S.; Cui, Q.; Pamukcu, A.; Berceau, B.; Xenias, H.; Higgs, M.; Rajamanickam, S.; Chen, Y.; Du, X.; Zhang, Y.; McMorrow, H.; Abecassis, Z.; Boca, S.; Justice, N.; Wilson, C.; Chan, C. S.
10.1101/2020.08.23.263053 — neuroscience — Posted on 2020-08-24
1161 Focal Electrical Stimulation of Human Retinal Ganglion Cells
Madugula, S.; Gogliettino, A. R.; Zaidi, M.; Aggarwal, G.; Kling, A.; Shah, N. P.; Vilkhu, R.; Hays, M.; Nguyan, H.; Fan, V.; Wu, E. G.; Hottowy, P.; Sher, A.; Litke, A. M.; Silva, R. A.; Chichilnisky, E. J.
10.1101/2020.08.23.263608 — neuroscience — Posted on 2020-08-24
1162 Overexpression of the transcription factor GROWTH-REGULATING FACTOR5 improves transformation of dicot and monocot species
Kong, J.; Martin-Ortigosa, S.; Finer, J.; Orchard, N.; Gunadi, A.; Batts, L. A.; Thakare, D.; Rush, B.; Schmitz, O.; Stuiver, M.; Olhoft, P.; Pacheco Villalobos, D.
10.1101/2020.08.23.263947 — plant biology — Posted on 2020-08-24
1166 Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy
Krieger, T. G.; LeBlanc-Soto, S.; Jabs, J.; Ten, F. W.; Ishaque, N.; Jechow, K.; Giri, A.; Eils, R.; Strobel, O.; Conrad, C.
10.1101/2020.08.23.263160 — cancer biology — Posted on 2020-08-24
1169 Graph of graphs analysis for multiplexed data with application to imaging mass cytometry
Lin, Y.-W. E.; Shnitzer, T.; Talmon, R.; Villaroel-Espindola, F.; Desai, S.; Schalper, K.; Kluger, Y.
10.1101/2020.08.23.263467 — bioinformatics — Posted on 2020-08-24
1172 How to limit the speed of a motor: The intricate regulation of the XPB ATPase and Translocase in TFIIH
Kappenberger, J.; Koelmel, W.; Schoenwetter, E.; Scheuer, T.; Woerner, J.; Kuper, J.; Kisker, C.
10.1101/2020.08.24.264176 — biochemistry — Posted on 2020-08-24
1173 Whole-organism mapping of the genetics of gene expression at cellular resolution
Ben-David, E.; Boocock, J.; Guo, L.; Zdraljevic, S.; Bloom, J. S.; Kruglyak, L.
10.1101/2020.08.23.263798 — genetics — Posted on 2020-08-24
1177 A genome-scale phylogeny of Fungi; insights into early evolution, radiations, and the relationship between taxonomy and phylogeny
Li, Y.; Steenwyk, J. L.; Chang, Y.; Wang, Y.; James, T. Y.; Stajich, J. E.; Spatafora, J. W.; Groenewald, M.; Dunn, C.; Hittinger, C. T.; Shen, X.-X.; Rokas, A.
10.1101/2020.08.23.262857 — evolutionary biology — Posted on 2020-08-24
1179 Cell intercalation driven by SMAD3 underlies secondary neural tube formation
Gonzalez-Gobartt, E.; Blanco-Ameijeiras, J. M.; Usieto, S.; Allio, G.; Benazeraf, B.; Marti, E.
10.1101/2020.08.24.261008 — developmental biology — Posted on 2020-08-24
1181 MRE11 is crucial for malaria transmission and its absence affects expression of interconnected networks of key genes essential for life
Guttery, D.; Ramaprasad, A.; Ferguson, D.; Zeeshan, M.; Pandey, R.; Brady, D.; Holder, A. A.; Pain, A.; Tewari, R.
10.1101/2020.08.24.258657 — cell biology — Posted on 2020-08-24
1182 Antiviral activity of a human placental protein of retroviral origin
Frank, J. A.; Singh, M.; Cullen, H. B.; Kirou, R. A.; Coyne, C. B.; Feschotte, C.
10.1101/2020.08.23.263665 — molecular biology — Posted on 2020-08-24
1183 Size matters: optimal mask diameter and box size for single-particle cryogenic electron microscopy
Moriya, T.; Adachi, N.; Kawasaki, M.; Yamada, Y.; Shinoda, A.; Koiwai, K.; Yumoto, F.; Senda, T.
10.1101/2020.08.23.263707 — molecular biology — Posted on 2020-08-24
1184 RUNX1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells: Mechanistic studies and drug correction
Estevez, B.; Borst, S.; Jarocha, D.; Sudunagunta, V.; Gonzalez, M.; Garifallou, J.; Hakonarson, H.; Gao, P.; Tan, K.; Liu, P. P.; Bagga, S.; Holdreith, N.; Tong, W.; Speck, N.; French, D.; Gadue, P.; Poncz, M.
10.1101/2020.08.23.260281 — molecular biology — Posted on 2020-08-24
1187 Single cell BCR and transcriptome analysis after respiratory virus infection reveals spatiotemporal dynamics of antigen-specific B cell responses.
Mathew, N. R.; Jayanthan, J. K.; Smirnov, I.; Robinson, J. L.; Axelsson, H.; Nakka, S. S.; Emmanouilidi, A.; Czarnewski, P.; Yewdell, W. T.; Lebrero-Fernandez, C.; Bernasconi, V.; Harandi, A. M.; Lycke, N.; Borcherding, N.; Yewdell, J. W.; Greiff, V.; Bemark, M.; Angeletti, D.
10.1101/2020.08.24.264069 — immunology — Posted on 2020-08-24
1189 Sleep and sleep deprivation differentially alter white matter microstructure: a mixed model design utilising advanced diffusion modelling
Voldsbekk, I.; Groote, I.; Zak, N.; Roelfs, D.; Geier, O.; Due-Tonnessen, P.; Lokken, L.-L.; Stromstad, M.; Blakstvedt, T. Y.; Kuiper, Y. S.; Elvsashagen, T.; Westlye, L. T.; Bjornerud, A.; Maximov, I. I.
10.1101/2020.08.24.259432 — neuroscience — Posted on 2020-08-24
1190 Temporally-Divergent Regulatory Mechanisms Govern Neuronal Development and Diversification in the Neocortex
Yuan, W.; Ma, S.; Kim, K.; Murek, V.; Trastulla, L.; Brown, J.; Meissner, A.; Lodato, S.; Shetty, A.; Levin, J. Z.; Buenrostro, J. D.; Ziller, M.; Arlotta, P.
10.1101/2020.08.23.263434 — neuroscience — Posted on 2020-08-24
1191 pMAT: An Open-Source Software Suite for the Analysis of Fiber Photometry Calcium Imaging
Bruno, C. A.; O'Brien, C.; Bryant, S.; Mejaes, J.; Pizzano, C.; Estrin, D. J.; Barker, D. J.
10.1101/2020.08.23.263673 — neuroscience — Posted on 2020-08-24
1192 The Japan Monkey Centre Primates Brain Imaging Repository of high-resolution postmortem magnetic resonance imaging: the second phase of the archive of digital records
Sakai, T.; Hata, J.; Shintaku, Y.; Ohta, H.; Sogabe, K.; Mori, S.; Okano, H. J.; Hamada, Y.; Hirabayashi, T.; Minamimoto, T.; Sadato, N.; Okano, H.; Oishi, K.
10.1101/2020.08.23.263517 — neuroscience — Posted on 2020-08-24
1198 Inheritance of Rootstock Effects in Avocado ( Persea americana Mill.) cv. Hass
Reyes-Herrera, P. H.; Munoz-Baena, L.; Velasquez-Zapata, V.; Patino, L.; Delgado-Paz, O. A.; Diaz-Diez, C. A.; Navas-Arboleda, A. A.; Cortes, A. J.
10.1101/2020.08.21.261883 — plant biology — Posted on 2020-08-24
1200 An in vitro grafting method to quantify mechanical forces of adhering tissues
Kawakatsu, Y.; Sawai, Y.; Kurotani, K.-i.; Shiratake, K.; Notaguchi, M.
10.1101/2020.08.21.260562 — plant biology — Posted on 2020-08-24
1202 Chemotaxonomic Investigation of Apocynaceae for Retronecine-Type Pyrrolizidine Alkaloids Using HPLC-MS/MS
Barny, L. A.; Tasca, J. A.; Sanchez, H. A.; Smith, C. R.; Koptur, S.; Livshultz, T.; Minbiole, K. P. C.
10.1101/2020.08.23.260091 — plant biology — Posted on 2020-08-24
1207 Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver
Chao, H.-W.; Lin, H.; Huang, Y.-S.; Fustin, J.-M.; Doi, M.; Chen, H.; Lai, H.-H.; Lin, S.-H.; Lee, Y.-L.; King, P.-C.; Hou, H.-S.; Chen, H.-W.; Young, P.-Y.
10.1101/2020.08.23.258699 — pathology — Posted on 2020-08-24
1209 Epigenetic reprogramming of plasmacytoid dendritic cells drives type I interferon-dependent differentiation of acute myeloid leukemias for therapeutic benefit
Salmon, J.; Todorovski, I.; Vervoort, S. J.; Stanley, K. L.; Kearney, C. J.; Martelotto, L.; Rossello, F.; Semple, T.; Mir Arnau, G.; Zethoven, M.; Bots, M.; Vidacs, E.; McArthur, K.; Gressier, E.; De Weerd, N.; Lichte, J.; Kelly, M. J.; Cluse, L.; Hogg, S. J.; Hertzog, P. J.; Kats, L.; De Carvalho, D. D.; Scheu, S.; Bedoui, S.; Kile, B. T.; Wei, A.; Dominguez, P. M.; Johnstone, R. W.
10.1101/2020.08.23.235499 — cancer biology — Posted on 2020-08-24
1210 Deciphering the mechanical code of genome and epigenome
Basu, A.; Bobrovnikov, D. G.; Cieza, B.; Qureshi, Z.; Ha, T.
10.1101/2020.08.22.262352 — biophysics — Posted on 2020-08-24
1211 Theoretical basis for stabilizing messenger RNA through secondary structure design
Wayment-Steele, H. K.; Kim, D. S.; Choe, C. A.; Nicol, J. J.; Wellington-Oguri, R.; Parra Sparberg, R. A.; Huang, P.; Eterna Massive Open Laboratory, ; Das, R.
10.1101/2020.08.22.262931 — biophysics — Posted on 2020-08-24
1222 Comprehensive genome sequencing analysis as a promising option in the prenatal diagnosis of fetal structural anomalies: a prospective study.
Zhou, J.; Yang, Z.; Sun, J.; Liu, L.; Zhou, X.; Liu, F.; Xing, Y.; Cui, S.; Xiong, S.; Liu, X.; Yang, Y.; Wei, X.; Zou, G.; Wang, Z.; Wei, X.; Wang, Y.; Zhang, Y.; Yan, S.; Wu, F.; Zeng, F.; Duan, T.; Wang, J.; Yang, Y.; Peng, Z.; Sun, L.
10.1101/2020.08.22.260893 — genomics — Posted on 2020-08-24
1224 Expansion dynamics and marginal climates drive adaptation across geographic ranges
Bontrager, M.; Usui, T.; Lee-Yaw, J. A.; Anstett, D. N.; Branch, H. A.; Hargreaves, A. L.; Muir, C. D.; Angert, A. L.
10.1101/2020.08.22.262915 — evolutionary biology — Posted on 2020-08-24
1225 Differential effects of redox conditions on the decomposition of litter and soil organic matter
Lin, Y.; Campbell, A. N.; Bhattacharyya, A.; Didonato, N.; Thompson, A. M.; Tfaily, M.; Nico, P. S.; Silver, W. L.; Pett-Ridge, J.
10.1101/2020.08.21.262246 — ecology — Posted on 2020-08-24
1228 Estimating the density of small population of leopard Panthera pardus using multi-session photographic-sampling data
Farhadinia, M.; Behnoud, P.; Hobeali, K.; Mousavi, S. J.; Hosseini-Zavarei, F.; Gholikhani, N.; Akbari, H.; Eslami, M.; Moghadas, P.; Macdonald, D.
10.1101/2020.08.22.262980 — ecology — Posted on 2020-08-24
1230 In vivo metabolite tracing of T cells
Sheldon, R. D.; Ma, E. H.; DeCamp, L. M.; Williams, K. S.; Jones, R. G.
10.1101/2020.08.21.261503 — molecular biology — Posted on 2020-08-24
1233 Connectomic Alterations Linked to Transdiagnostic Risk for Psychopathology at the Transition to Adolescence
Sripada, C.; Angstadt, M.; Rutherford, S.; Taxali, A.; Greathouse, T.; Clark, D. A.; Hyde, L.; Weigard, A.; Brislin, S.; Hicks, B.; Heitzeg, M.
10.1101/2020.08.21.260927 — neuroscience — Posted on 2020-08-24
1237 Generative lesion pattern decomposition of cognitive impairment after stroke
Bonkhoff, A. K.; Lim, J.-S.; Bae, H.-J.; Weaver, N. A.; Kuijf, H. J.; Biesbroek, J. M.; Rost, N. S.; Bzdok, D.
10.1101/2020.08.22.262873 — neuroscience — Posted on 2020-08-24
1241 Jaw Kinematics and Tongue Protraction-Retraction during Chewing and Drinking in the Pig
Olson, R. A.; Montuelle, S. J.; Chadwell, B. A.; Curtis, H.; Williams, S. H.
10.1101/2020.08.22.261602 — physiology — Posted on 2020-08-24
1250 The medaka alg2 mutant is a model for hypo-N-glycosylation-associated retinitis pigmentosa
Gücüm, S.; Sakson, R.; Hoffmann, M.; Grote, V.; Beedgen, L.; Thiel, C.; Rapp, E.; Ruppert, T.; Wittbrodt, J.; Thumberger, T.
10.1101/2020.08.20.260430 — developmental biology — Posted on 2020-08-24
1251 Impaired cytotoxic CD8+ T cell response in elderly COVID-19 patients
Westmeier, J.; Paniskaki, K.; Karaköse, Z.; Werner, T.; Sutter, K.; Dolff, S.; Overbeck, M.; Limmer, A.; Liu, J.; Zheng, X.; Brenner, T.; Berger, M. M.; Witzke, O.; Trilling, M.; Lu, M.; Yang, D.; Babel, N.; Westhoff, T.; Dittmer, U.; Zelinskyy, G.
10.1101/2020.08.21.262329 — immunology — Posted on 2020-08-24
1257 Genome assembly of a Mesoamerica-derived Phaseolus lunatus cultivar enables the identification and comparative genomic analysis of a complex resistance locus
Wisser, R.; Oppenheim, S. J.; Ernest, E. G.; Mhora, T. T.; Scanlan, C.; Dumas, M. D.; Gregory, N. F.; Evans, T. A.; Donofrio, N.
10.1101/2020.08.19.257105 — genomics — Posted on 2020-08-23
1259 Consistent variations in personality traits and their potential for genetic improvement in the biocontrol agent Trichogramma evanescens
Lartigue, S.; Yalaoui, M.; Belliard, J.; Caravel, C.; Jeandroz, L.; Groussier, G.; Calcagno, V.; Louapre, P.; Dechaume-Moncharmont, F.-X.; Malausa, T.; Moreau, J.
10.1101/2020.08.21.257881 — ecology — Posted on 2020-08-23
1260 LoVIS-Seq reveals clonal dynamics of human-HSPC in humanized mice and vector integration bias
Suryawanshi, G. W.; Arokium, H.; Kim, S.; Khamaikawin, W.; Lin, S.; Shimizu, S.; Chupradit, K.; Lee, Y.; Xie, Y.; Guan, X.; Suryawanshi, V.; Presson, A. P.; An, D.-S.; Chen, I. S. Y.
10.1101/2020.08.21.261537 — molecular biology — Posted on 2020-08-23
1262 Host age shapes virome abundance and diversity in birds
Wille, M.; Shi, M.; Hurt, A. C.; Klaassen, M.; Holmes, E.
10.1101/2020.08.23.263103 — microbiology — Posted on 2020-08-23
1263 Zoonotic viruses in three species of voles (Microtus spp.) from Poland
Grzybek, M.; Tolkacz, K.; Sironen, T.; Maki, S.; Alsarraf, M.; Behnke-Borowczyk, J.; Biernat, B.; Nowicka, J.; Vaheri, A.; Henttonen, H.; Behnke, J.; Bajer, A.
10.1101/2020.08.22.259309 — microbiology — Posted on 2020-08-23
1265 Structure of population activity in primary motor cortex for single finger flexion and extension
Arbuckle, S. A.; Weiler, J.; Kirk, E. A.; Rice, C. L.; Schieber, M. H.; Pruszynski, J. A.; Ejaz, N.; Diedrichsen, J.
10.1101/2020.03.17.996124 — neuroscience — Posted on 2020-08-23
1267 A Multimodal and Integrated Approach to Interrogate Human Kidney Biopsies with Rigor and Reproducibility: The Kidney Precision Medicine Project
El-Achkar, T. M.; Eadon, M. T.; Menon, R.; Lake, B. B.; Sigdel, T. K.; Alexandrov, T.; Parikh, S.; Zhang, G.; Dobi, D.; Dunn, K. W.; Otto, E. A.; Anderton, C. R.; Carson, J. M.; Luo, J.; Park, C.; Hamidi, H.; Zhou, J.; Hoover, P.; Schroeder, A.; Joanes, M.; Azeloglu, E.; Sealfon, R.; Winfree, S.; Steck, B.; He, Y.; D'Agati, V. D.; Iyengar, R.; Troyanskaya, O. G.; Barisoni, L.; Gaut, J.; Zhang, K.; Laszik, Z.; Rovin, B.; Dagher, P. C.; Sharma, K.; Sarwal, M.; Hodgin, J. B.; Alpers, C. E.; Kretzler, M.; Jain, S.; For the Kidney Precision Medicine Project,
10.1101/828665 — scientific communication and education — Posted on 2020-08-23
1272 High Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Metabolism of Uveal Melanoma Cells.
Slater, K.; Heeran, A. B.; Sanz-Pamplona, R.; Kalirai, H.; Rahman, A.; Helmi, M.; Garcia-Mulero, S.; O'Connell, F.; Bosch, R.; Portela, A.; Villanueva, A.; Piulats, J. M.; Gallagher, W. M.; Jensen, L. D.; Coupland, S. E.; O'Sullivan, J.; Kennedy, B. N.
10.1101/2020.08.23.261545 — cancer biology — Posted on 2020-08-23
1273 Ebselen Reacts with SARS Coronavirus-2 Main Protease Crystals
Malla, T. N.; Pandey, S.; Poudyal, I.; Feliz, D.; Noda, M.; Phillips, G.; Stojkovic, E.; Schmidt, M.
10.1101/2020.08.10.244525 — biophysics — Posted on 2020-08-23
1277 Evolution of flowering time in a selfing annual plant: Roles of adaptation and genetic drift
Gay, L.; Dhinaut, J.; Jullien, M.; Vitalis, R.; Navascues, M.; Ranwez, V.; Ronfort, J.
10.1101/2020.08.21.261230 — evolutionary biology — Posted on 2020-08-23
1278 A novel fluorescence and DNA combination for complex, long-term marking of mosquitoes
Faiman, R.; Krajacich, B. J.; Graber, L.; Dao, A.; Yaro, A. S.; Ousmane Yossi, O. Y.; Sanogo, Z. L.; Diallo, M.; Samake, D.; Sylla, D.; Coulibaly, M.; Kone, S. M.; Goita, S.; Coulibaly, M. B.; Muratova, O.; McCormack, A.; Goncalves, B. P.; Hume, J.; Duffy, P.; Lehmann, T.
10.1101/2020.08.23.262741 — ecology — Posted on 2020-08-23
1281 NLRP3 inflammasome contributes to host defense against Talaromyces marneffei infection
Ma, H.; Chan, J. F.-W.; Tan, Y. P.; Kui, L.; Tsang, C.-C.; Pei, S. L.; Lau, Y.-L.; Woo, P. C.; Lee, P. P.
10.1101/2020.08.17.253518 — microbiology — Posted on 2020-08-23
1286 Microbial activation converts neutrophils into anti-tumor effectors
Yam, A. O.; Bailey, J.; Lin, F.; Jakovija, A.; Counoupas, C.; Triccas, J. A.; Gunzer, M.; Bald, T.; Grey, S. T.; Chtanova, T.
10.1101/2020.08.21.259051 — immunology — Posted on 2020-08-23
1287 Modeling Genetic Epileptic Encephalopathies using Brain Organoids
Steinberg, D. J.; Saleem, A.; Repudi, S. R.; Banne, E.; Mahajnah, M.; Hanna, J. H.; Carlen, P. L.; Aqeilan, R. I.
10.1101/2020.08.23.263236 — neuroscience — Posted on 2020-08-23
1288 Breast cancer endocrine therapy exhausts adipocyte progenitors promoting weight gain and glucose intolerance
Scalzo, R. L.; Foright, R. M.; Hull, S. E.; Knaub, L. A.; Johnson-Murguia, S.; Kinanee, F.; Kaplan, J.; Freije, B.; Verzosa, G.; Houck, J. A.; Johnson, G.; Zhang, A. M. Y.; Johnson, J. D.; MacLean, P. S.; Reusch, J. E. B.; Wright-Hobart, S.; Wellberg, E. A.
10.1101/2020.08.21.259440 — physiology — Posted on 2020-08-23
1290 MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions
Backx, E.; Rooman, I.; Baldan, J.; Van Bulck, M.; Michiels, E.; Houbracken, I.; Heremans, Y.; Bouwens, L.; Wauters, E.; Jacquemin, P.; De Paep, D. L.; Goyama, S.; Kurokawa, M.
10.1101/2020.08.21.260539 — cancer biology — Posted on 2020-08-23
1291 CG7379/ING1 suppress cancer cell invasion by maintaining cell-cell junction integrity
Rusu, A. D.; Cornhill, Z. E.; Canales Coutino, B.; Castellanos Uribe, M.; Lourdusamy, A.; Markus, Z.; May, S. T.; Rahman, R.; Georgiou, M.
10.1101/2020.08.20.255786 — cancer biology — Posted on 2020-08-23
1303 Mutanofactin promotes bacterial adhesion and biofilm formation of cariogenic Streptococcus mutans
Li, Z.; Du, Y.; Sun, J.; Pan, A.; Zeng, L.; Maboudian, R.; Burne, R. A.; Qian, P.-Y.; Zhang, W.
10.1101/2020.08.22.262196 — microbiology — Posted on 2020-08-23
1305 Eliminating accidental deviations to minimize generalization error: applications in connectomics and genomics
Bridgeford, E. W.; Wang, S.; Yang, Z.; Wang, Z.; Xu, T.; Craddock, C.; Dey, J.; Kiar, G.; Gray-Roncal, W.; Coulantoni, C.; Douville, C.; Priebe, C. E.; Caffo, B.; Milham, M.; Zuo, X.-N.; Consortium for Reliability and Reproducibility, ; Vogelstein, J. T.
10.1101/802629 — neuroscience — Posted on 2020-08-23
1310 Contributions by N-terminal Domains to NMDA Receptor Currents
Amico-Ruvio, S. A.; Paganelli, M. A.; Abbott, J. A.; Myers, J. M.; Kasperek, E. M.; Iacobucci, G. J.; Popescu, G. K.
10.1101/2020.08.21.261388 — biophysics — Posted on 2020-08-23
1311 Emap2sec+: Detecting Protein and DNA/RNA Structures in Cryo-EM Maps of Intermediate Resolution Using Deep Learning
Wang, X.; Alnabati, E.; Aderinwale, T. W.; Maddhuri Venkata Subramaniya, S. R.; Terashi, G.; Kihara, D.
10.1101/2020.08.22.262675 — biophysics — Posted on 2020-08-23
1316 A Non-stop identity complex (NIC) supervises enterocyte identity and protects from pre-mature aging
Erez, N.; Israitel, L.; Bitman-Lotan, E.; Wong, W. H.; Raz, G.; Danial, S.; Flint-Brodasly, N.; Belova, E.; Maksimenko, O.; Georgiev, P.; Druley, T.; Mohan, R.; Orian, A. M.
10.1101/2020.08.23.263095 — cell biology — Posted on 2020-08-23
1317 Evaluation of SARS-CoV-2 neutralizing antibodies using a vesicular stomatitis virus possessing SARS-CoV-2 spike protein
Tani, H.; Tan, L.; Kimura, M.; Yoshida, Y.; Yamada, H.; Fukushi, S.; Saijo, M.; Kawasuji, H.; Ueno, A.; Miyajima, Y.; Fukui, Y.; Sakamaki, I.; Yamamoto, Y.; Morinaga, Y.
10.1101/2020.08.21.262295 — microbiology — Posted on 2020-08-23
1318 Lipid droplets fuels SARS-CoV-2 replication and inflammatory response
Gomes Dias, S. S.; Cardoso, V. S.; Ferreira, A. C.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Temerozo, J. R.; Teixeira, L.; Barreto, E. A.; Mattos, M.; de Freitas, C. S.; Azevedo-Quintanilha, I.; Manso, P. P. A.; Hottz, E. D.; Pao, C. R. R.; Bou-Habib, D. C.; Bozza, F. A.; Souza, T. M. L.; Bozza, P. T.
10.1101/2020.08.22.262733 — immunology — Posted on 2020-08-23
1320 Identification of MYOM2 as a candidate gene in hypertrophic cardiomyopathy and Tetralogy of Fallot and its functional evaluation in the Drosophila heart
Auxerre-Plantie, E.; Nielsen, T.; Grunert, M.; Olejniczak, O.; Perrot, A.; Oezcelik, C.; Harries, D.; Matinmehr, F.; Remedios, C. D.; Muehlfeld, C.; Kraft, T.; Bodmer, R.; Vogler, G.; R. Sperling, S.
10.1101/2020.08.18.255760 — genetics — Posted on 2020-08-23
1321 Scaffold-scaffold interactions regulate cell polarity in a bacterium
Zhao, W.; Duvall, S. W.; Kowallis, K. A.; Zhang, C.; Tomares, D.; Petitjean, H.; Childers, W. S.
10.1101/2020.08.21.262345 — microbiology — Posted on 2020-08-23
1322 Pre-existing cutaneous conditions could increase the risk for SARS-COV-2 infection.
Xu, Q.; Chen, L.; Zhang, L.; Hu, M.; Wang, X.; Yang, Q.; Le, Y.; Xue, F.; Li, X.; Zheng, J.
10.1101/2020.06.30.181297 — pathology — Posted on 2020-08-23
1325 Active Perception during Angiogenesis: Filopodia speed up Notch selection of tip cells in silico and in vivo
Zakirov, B.; Charalambous, G.; Aspalter, I. M.; Van-Vuuren, K.; Mead, T.; Harrington, K.; Thuret, R.; Ravasz Regan, E.; Herbert, S. P.; Bentley, K.
10.1101/2020.08.22.261263 — cell biology — Posted on 2020-08-23
1326 Predicting Sex from Resting-State fMRI Across Multiple Independent Acquired Datasets
AL Zoubi, O.; Misaki, M.; Tsuchiyagaito, A.; Zotev, V.; White, E.; T1000 Investigators, ; Paulus, M. P.; Bodurka, J.
10.1101/2020.08.20.259945 — neuroscience — Posted on 2020-08-23
1328 Defining the early stages of intestinal colonisation by whipworms
Duque Correa, M. A.; Goulding, D.; Cormie, C.; Sharpe, C.; Gali Moya, J.; Ridley, C.; McCarthy, C.; Hayes, K. S.; Bancroft, A. J.; Carneiro, C. M.; Starborg, T.; Thornton, D. J.; Grencis, R. K.; Berriman, M.
10.1101/2020.08.21.261586 — immunology — Posted on 2020-08-23
1329 Whole-animal connectome and cell-type complement of the three-segmented Platynereis dumerilii larva
Veraszto, C.; Jasek, S.; Gühmann, M.; Shahidi, R.; Ueda, N.; Beard, J. D.; Mendes, S.; Heinz, K.; Bezares-Calderon, L. A.; Williams, E. A.; Jekely, G.
10.1101/2020.08.21.260984 — neuroscience — Posted on 2020-08-23
1332 Retinal mechanisms of saccadic suppression and their role in processing sequential stimuli
Idrees, S.; Baumann, M. P.; Korympidou, M.; Schubert, T.; Kling, A.; Franke, K.; Hafed, Z. M.; Franke, F.; Münch, T. A.
10.1101/2020.08.21.261198 — neuroscience — Posted on 2020-08-23
1334 An Engrailed1 enhancer underlies human thermoregulatory evolution
Aldea, D.; Atsuta, Y.; Kokalari, B.; Schaffner, S.; Warder, B.; Kamberov, Y. G.
10.1101/2020.08.22.262659 — evolutionary biology — Posted on 2020-08-23
1337 Molecular characterization of selectively vulnerable neurons in Alzheimer's Disease
Leng, K.; Li, E.; Eser, R.; Piergies, A.; Sit, R.; Tan, M.; Neff, N.; Li, S. H.; Diehl Rodriguez, R.; Suemoto, C. K.; Paraizo Leite, R. E.; Pasqualucci, C. A.; Seeley, W. W.; Spina, S.; Heinsen, H.; Grinberg, L. T.; Kampmann, M.
10.1101/2020.04.04.025825 — neuroscience — Posted on 2020-08-23
1339 Temporal dynamics of visual representations in the infant brain
Bayet, L.; Zinszer, B. D.; Reilly, E.; Cataldo, J. K.; Pruitt, Z.; Cichy, R. M.; Nelson, C. A.; Aslin, R. N.
10.1101/2020.02.26.947911 — neuroscience — Posted on 2020-08-23
1342 Molecular basis for substrate recruitment to the PRMT5 methylosome
Mulvaney, K. M.; Blomquist, C.; Acharya, N.; Li, R.; OKeefe, M.; Ranaghan, M.; Stokes, M.; Nelson, A. J.; Jain, S. S.; Columbus, J.; Bozal, F. K.; Skepner, A.; Raymond, D.; McKinney, D. C.; Freyzon, Y.; Baidi, Y.; Porter, D.; Ianari, A.; McMillan, B.; Sellers, W. R.
10.1101/2020.08.22.256347 — cancer biology — Posted on 2020-08-22
1343 De novo reconstruction of microbial haplotypes by integrating statistical and physical linkage
Cao, C.; He, J.; Mak, L.; Perera, D.; Kwok, D.; Wang, J.; Li, M.; Mourier, T.; Gavriliuc, S.; Greenberg, M.; Morrissy, S.; Sycuro, L.; Yang, G.; Jeffares, D. C.; Long, Q.
10.1101/2020.03.29.014704 — bioinformatics — Posted on 2020-08-22
1346 Evolution of dynamical networks enhances catalysis in a designer enzyme
Bunzel, H. A.; Anderson, R.; Hilvert, D.; Arcus, V. L.; van der Kamp, M. W.; Mulholland, A. J.
10.1101/2020.08.21.260885 — biochemistry — Posted on 2020-08-23
1352 Mass Spectrometric Characterization of Narcolepsy-Associated Pandemic 2009 Influenza Vaccines.
Ambati, A.; Luo, G.; Pradhan, E.; Jacob, L.; Lin, L.; Leib, R.; Ollila, H. M.; Poiret, T.; Adams, C.; Mignot, E.
10.1101/2020.08.21.256180 — immunology — Posted on 2020-08-22
1353 A Platform Incorporating Trimeric Antigens into Self-Assembling Nanoparticles Reveals SARS-CoV-2-Spike Nanoparticles to Elicit Substantially Higher Neutralizing Responses than Spike Alone
Zhang, B.; Chao, C. W.; Tsybovsky, Y.; Abiona, O. M.; Hutchinson, G. B.; Moliva, J. I.; Olia, A. S.; Pegu, A.; Phung, E.; Stewart-Jones, G.; Verardi, R.; Wang, L.; Wang, S.; Werner, A.; Yang, E. S.; Yap, C.; Zhou, T.; Mascola, J. R.; Sullivan, N. J.; Graham, B. S.; Corbett, K. S.; Kwong, P. D.
10.1101/2020.06.11.147496 — immunology — Posted on 2020-08-23
1355 Auditory Corticothalamic Neurons are Recruited by Motor Preparatory Inputs
Clayton, K. K.; Williamson, R. S.; Hancock, K. E.; Hackett, T.; Polley, D. B.
10.1101/2020.05.28.121459 — neuroscience — Posted on 2020-08-22
1356 Real-time suppression and amplification of frequency-specific neural activity using stimulation evoked oscillations
Escobar Sanabria, D.; Johnson, L. A.; Yu, Y.; Busby, Z.; Nebeck, S.; Zhang, J.; Harel, N.; Johnson, M. D.; Molnar, G. F.; Vitek, J. L.
10.1101/2020.02.09.940643 — neuroscience — Posted on 2020-08-22
1359 Ectopic histone clipping in the mouse model of progressive myoclonus epilepsy
Daura, E.; Tegelberg, S.; Yoshihara, M.; Jackson, C.; Simonetti, F.; Aksentjeff, K.; Ezer, S.; Hakala, P.; Katayama, S.; Kere, J.; Lehesjoki, A.-E.; Joensuu, T.
10.1101/2020.08.21.261180 — pathology — Posted on 2020-08-22
1360 Modeling the Role of Hypoxia in Glioblastoma Growth and Recurrence Patterns
Curtin, L.; Hawkins-Daarud, A.; Porter, A. B.; Owen, M. R.; van der Zee, K. G.; Swanson, K. R.
10.1101/691238 — cancer biology — Posted on 2020-08-22
1361 Recurrent human papillomavirus-related head and neck cancer undergoes metabolic re-programming and is driven by oxidative phosphorylation
VYAS, A.; Harbison, R. A.; Faden, D.; Kubik, M.; Palmer, D.; Zhang, Q.; Osmanbeyoglu, H.; Mendez, E.; Duvvuri, U.
10.1101/2020.08.21.261206 — cancer biology — Posted on 2020-08-22
1362 A Mechanistic Investigation into Ischemia-Driven Distal Recurrence of Glioblastoma
Curtin, L.; Hawkins-Daarud, A.; Porter, A. B.; van der Zee, K. G.; Owen, M. R.; Swanson, K. R.
10.1101/2020.04.03.022202 — cancer biology — Posted on 2020-08-22
1363 Methionine stress induces ferroptosis in methionine dependent cancer cells
Wallis, K. F.; Bird, J. T.; Gies, A. J.; Mackintosh, S. G.; Tackett, A. J.; Byrum, S.; Miousse, I. R.
10.1101/2020.08.18.254490 — cancer biology — Posted on 2020-08-22
1366 Renewable Fatty Acid Ester Production in Clostridium
Feng, J.; Zhang, J.; Feng, Y.; Wang, P.; Jimenez-Bonilla, P.; Gu, Y.; Zhou, J.; Zhang, Z.-T.; Cao, M.; Shao, Z.; Borovok, I.; Huang, H.; Wang, Y.
10.1101/2020.03.29.014746 — bioengineering — Posted on 2020-08-22
1371 Converging evidence for shared genetic underpinnings of genetic generalized epilepsy and EEG beta power
Stevelink, R.; Luykx, J. J.; Lin, B.; Leu, C.; Lal, D.; Smith, A.; Schijven, D.; Carpay, J.; Rademaker, K.; Baldez, R.; Braun, K.; Jansen, F.; Epi25 Collaborative, ; ILAE Consortium, ; Smit, D.; Koeleman, B.
10.1101/711200 — genetics — Posted on 2020-08-22
1373 Tripartite separation of glomerular cell-types and proteomes from reporter-free mice
Hatje, F. A.; Rinschen, M. M.; Wedekind, U.; Sachs, W.; Reichelt, J.; Huber, T. B.; Skuza, S.; Sachs, M.; Zielinski, S.; Meyer-Schwesinger, C.
10.1101/2020.08.22.262584 — cell biology — Posted on 2020-08-22
1374 Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines
He, L.; Chaudhary, A.; Lin, X.; Sou, C.; Kumar, S.; Ngo, T.; Kosivner, E.; Stanfield, R.; Wilson, I.; Zhu, J.
10.1101/2020.08.22.262634 — microbiology — Posted on 2020-08-22
1379 Hematopoietic lineages diverge within the stem cell compartment
Morcos, M. N. F.; Li, C.; Munz, C. M.; Greco, A.; Dressel, N.; Reinhardt, S.; Dahl, A.; Becker, N. B.; Roers, A.; Hofer, T.; Gerbaulet, A.
10.1101/2020.08.21.261552 — systems biology — Posted on 2020-08-22
1380 Attribution of genetic engineering: a practical and accurate machine learning toolkit for biosecurity
Alley, E. C.; Turpin, M.; Liu, A. B.; Kulp-McDowall, T.; Swett, J.; Edison, R.; Von Stetina, S. E.; Church, G. M.; Esvelt, K. M.
10.1101/2020.08.22.262576 — synthetic biology — Posted on 2020-08-22
1382 Serial femtosecond and serial synchrotron crystallography yield data of equivalent quality: a systematic comparison
Mehrabi, P.; Buecker, R.; Bourenkov, G.; Ginn, H.; von Stetten, D.; Mueller-Werkmeister, H. M.; Kuo, A.; Morizumi, T.; Eger, B.; Ou, W.-L.; Oghbaey, S.; Sarracini, A.; Besaw, J.; Pare-Labrosse, O.; Meier, S.; Schikora, H.; Tellkamp, F.; Marx, A.; Sherrell, D. A.; Axford, D.; Owen, R. L.; Ernst, O. P.; Pai, E. F.; Schulz, E. C.; Miller, R. J. D.
10.1101/2020.08.21.257170 — biophysics — Posted on 2020-08-22
1383 Generating hard-to-obtain information from easy-to-obtain information: applications in drug discovery and clinical inference
Amodio, M.; Shung, D.; Burkhardt, D. B.; Wong, P.; Simonov, M.; Yamamoto, Y.; van Dijk, D.; Wilson, F. P.; Iwasaki, A.; Krishnaswamy, S.
10.1101/2020.08.20.259598 — bioinformatics — Posted on 2020-08-22
1384 Automated analysis of rabbit knee calcified cartilage morphology using micro-computed tomography and deep learning segmentation
Rytky, S. J. O.; Huang, L.; Tanska, P.; Tiulpin, A.; Panfilov, E.; Herzog, W.; Korhonen, R. K.; Saarakkala, S.; Finnilä, M. A. J.
10.1101/2020.08.21.260992 — bioinformatics — Posted on 2020-08-22
1386 Regulation of extracellular matrix assembly and structure by hybrid M1/M2 macrophages
Witherel, C. E.; Sao, K.; Brisson, B. K.; Han, B.; Volk, S. W.; Petrie, R. J.; Han, L.; Spiller, K. L.
10.1101/2020.08.21.261933 — bioengineering — Posted on 2020-08-22
1387 Mantis shrimp rank the shape of an object over its color during recognition
Patel, R. N.; Khil, V.; Abdurahmonova, L.; Driscoll, H.; Patel, S.; Pettyjohn-Robin, O.; Shah, A.; Goldwasser, T.; Sparklin, B.; Cronin, T. W.
10.1101/2020.08.20.259903 — animal behavior and cognition — Posted on 2020-08-22
1391 Simultaneous transcriptome and methylome profiles of single mouse oocytes provide novel insights on maturation and aging
Qian, Y.; Cao, Q.; Liao, J.; Luk, C. S.; SUEN, A. H. C.; Lee, A. W. T.; Chan, T. H. T.; Ng, J. K. W.; Tang, N. L. S.; Chung, H. S.; Chow, K. L.; Leung, T. Y.; Chen, C.-H.; Yang, W.-J.; Huang, J. Y. J.; Chan, W.-Y.; Chan, D. Y. L.; Li, T. C.; Yip, K. Y.; Lee, T. L.
10.1101/2020.08.22.260612 — genomics — Posted on 2020-08-22
1393 Somatic deficiency causes reproductive parasitism in a fungus
Grum-Grzhimaylo, A. A.; Bastiaans, E.; van den Heuvel, J.; Berenguer Millanes, C.; Debets, A. J. M.; Aanen, D. K.
10.1101/2020.08.21.260869 — evolutionary biology — Posted on 2020-08-22
1394 Live imaging of avian embryos revealing a new head precursor map and the role for the anterior mesendoderm in brain development
Yoshihi, K.; Kato, K.; Iida, H.; Teramoto, M.; Kawamura, A.; Watanabe, Y.; Nunome, M.; Nakano, M.; Matsuda, Y.; Sato, Y.; Mizuno, H.; Iwasato, T.; Ishii, Y.; Kondoh, H.
10.1101/2020.08.22.262436 — developmental biology — Posted on 2020-08-22
1399 Defining the early stages of intestinal colonisation by whipworms
Duque Correa, M. A.; Goulding, D.; Cormie, C.; Sharpe, C.; Gali Moya, J.; Ridley, C.; McCarthy, C.; Hayes, K. S.; Bancroft, A. J.; Carneiro, C. M.; Starborg, T.; Thornton, D. J.; Grencis, R. K.; Berriman, M.
10.1101/2020.08.21.261586 — immunology — Posted on 2020-08-22
1400 The receptor binding domain of SARS-CoV-2 spike is the key target of neutralizing antibody in human polyclonal sera.
Steffen, T.; Stone, E. T.; Hassert, M.; Geerling, E.; Grimberg, B. T.; Espino, A. M.; Pantoja, P.; Climent, C.; Hoft, D. F.; George, S. L.; Sariol, C. A.; Pinto, A. K.; Brien, J. D.
10.1101/2020.08.21.261727 — immunology — Posted on 2020-08-22
1401 T-bet fate mapping identifies a novel ILC1-ILC2 subset in vivo
SCHROEDER, J.-H.; Garrido-Mesa, N.; Zabinski, T.; Gallagher, A.; Campbell, L.; Roberts, L.; Stolarczyk, E.; Beattie, G.; Lo, J.; Iseppon, A.; Moreira Heliodoro, C.; Reis, R.; Jenner, R.; Lavender, P.; Howard, J.; Grencis, R.; Helmby, H.; Neves, J.; Lord, G.
10.1101/2020.08.21.261073 — immunology — Posted on 2020-08-22
1402 Alternative splicing of SLAMF6 in human T cells creates a co-stimulatory isoform that counteracts the inhibitory effect of the full-length receptor
Hajaj, E.; Zisman, E.; Tzaban, S.; Merims, S.; Cohen, J. E.; Klein, S.; Frankenburg, S.; Sade-Feldman, M.; Tabach, Y.; Yizhak, K.; Navon, A.; Stepensky, P.; Hacohen, N.; Peretz, T.; Veillette, A.; Karni, R.; Eisenberg, G.; Lotem, M.
10.1101/2020.08.21.262238 — immunology — Posted on 2020-08-22
1404 Investigating real-life emotions in romantic couples: a mobile EEG study
Packheiser, J.; Berretz, G.; Rook, N.; Schockenhoff, L.; Bahr, C.; Guentuerkuen, O.; Ocklenburg, S.
10.1101/2020.08.20.259796 — neuroscience — Posted on 2020-08-22
1405 A generic decision-making ability predicts psychopathology in adolescents and young adults and is reflected in distinct brain connectivity patterns
Moutoussis, M.; Garzon, B.; Neufeld, S.; Bach, D.; Rigoli, F.; Neuroscience in Psychiatry Network, ; Guitart-Masip, M.; Dolan, R. J.
10.1101/2020.08.20.259697 — neuroscience — Posted on 2020-08-22
1406 Whole-animal connectome and cell-type complement of the three-segmented Platynereis dumerilii larva
Veraszto, C.; Jasek, S.; Gühmann, M.; Shahidi, R.; Ueda, N.; Beard, J. D.; Mendes, S.; Heinz, K.; Bezares-Calderon, L. A.; Williams, E. A.; Jekely, G.
10.1101/2020.08.21.260984 — neuroscience — Posted on 2020-08-22
1410 Sphagnum peat moss thermotolerance is modulated by the microbiome
Carrell, A. A.; Lawrence, T. J.; Cabugao, K. G. M.; Carper, D. L.; Pelletier, D. A.; Jawdy, S.; Grimwood, J. A.; Schmutz, J.; Hanson, P. J.; Shaw, A. J.; Weston, D. J.
10.1101/2020.08.21.259184 — plant biology — Posted on 2020-08-22
1412 CLEP: A Hybrid Data- and Knowledge- Driven Framework for Generating Patient Representations
Bharadhwaj, V. S.; Ali, M.; Birkenbihl, C.; Mubeen, S.; Lehmann, J.; Hofmann-Apitius, M.; Hoyt, C. T.; Domingo-Fernandez, D.
10.1101/2020.08.20.259226 — bioinformatics — Posted on 2020-08-22
1413 Recombinant SARS-CoV-2 RBD molecule with a T helper epitope as a built in adjuvant induces strong neutralization antibody response
Su, Q.; Zou, Y.; Yi, Y.; Shen, L.; Ye, C.; Zhang, Y.; Wang, H.; Ke, H.; Song, J.; Hu, K.; Cheng, B.; Qiu, F.; Yu, P.; Zhou, W.; Cao, L.; Bi, S.; Wu, G.; Gao, G. F.; Zheng, J.
10.1101/2020.08.21.262188 — bioengineering — Posted on 2020-08-22
1414 A sort-seq approach to the development of single fluorescent protein biosensors
Koberstein, J. N.; Stewart, M. L.; Mighell, T. L.; Smith, C. B.; Cohen, M. S.
10.1101/2020.08.21.261578 — biochemistry — Posted on 2020-08-22
1415 Deep Graph Pose: a semi-supervised deep graphical model for improved animal pose tracking
Wu, A.; Buchanan, E. K.; Whiteway, M. R.; Schartner, M.; Meijer, G. T.; Noel, J.-P.; Rodriguez, E.; Everett, C.; Norovich, A.; Schaffer, E. S.; Mishra, N.; Salzman, C. D.; Angelaki, D. E.; International Brain Laboratory, T.; Cunningham, J. P.; Paninski, L.
10.1101/2020.08.20.259705 — animal behavior and cognition — Posted on 2020-08-22
1416 Too much too many: comparative analysis of morabine grasshopper genomes reveals highly abundant transposable elements and rapidly proliferating satellite DNA repeats
Palacios-Gimenez, O. M.; Koelman, J.; Palmada-Flores, M.; Bradford, T. M.; Jones, K. K.; Cooper, S. J. B.; Kawakami, T.; Suh, A.
10.1101/2020.08.22.247130 — genomics — Posted on 2020-08-22
1418 Evidence for a role of phenotypic mutations in virus adaptation
Luzon-Hidalgo, R.; Risso, V. A.; Delgado, A.; Andres-Leon, E.; Ibarra-Molero, B.; Sanchez-Ruiz, J. M.
10.1101/2020.08.21.261495 — evolutionary biology — Posted on 2020-08-22
1420 Ferrets not infected by SARS-CoV-2 in a high-exposure domestic setting
Sawatzki, K.; Hill, N. J.; Puryear, W. B.; Foss, A. D.; Stone, J. J.; Runstadler, J. A.
10.1101/2020.08.21.254995 — molecular biology — Posted on 2020-08-22
1423 Genome-scale mapping reveals complex regulatory activities of RpoN in Yersinia pseudotuberculosis
Mahmud, A. K. M. F.; Nilsson, K.; Fahlgren, A.; Navais, R.; Choudhury, R.; Avican, K.; Fällman, M.
10.1101/2020.08.19.258541 — microbiology — Posted on 2020-08-22
1426 Neural and subjective effects of inhaled DMT in natural settings
Pallavicini, C.; Cavanna, F.; Zamberlan, F.; de la Fuente, L. A.; Sanz Perl, Y.; Arias, M.; Romero, M. C.; Carhart-Harris, R.; Timmermann, C.; Tagliazucchi, E.
10.1101/2020.08.19.258145 — neuroscience — Posted on 2020-08-22
1427 Circadian modulation of neurons and astrocytes controls synaptic plasticity in hippocampal area CA1
McCauley, J.; Petroccione, M.; D'Brant, L.; Todd, G.; Affinnih, N.; Wisnoski, J.; Zahid, S.; Shree, S.; Sousa, A.; Migliore, R.; Brazhe, A.; Leapman, R.; Khmaladze, A.; Semyanov, A.; Migliore, M.; Scimemi, A.
10.1101/666073 — neuroscience — Posted on 2020-08-22
1428 Single-nuclei transcriptomics of schizophrenia prefrontal cortex primarily implicates neuronal subtypes
Reiner, B. C.; Crist, R. C.; Stein, L. M.; Weller, A. E.; Doyle, G. A.; Arauco-Shapiro, G.; Ferraro, T. N.; Hayes, M. R.; Berrettini, W. H.
10.1101/2020.07.29.227355 — neuroscience — Posted on 2020-08-22
1429 Epigenome dysregulation resulting from NSD1 mutation in head and neck squamous cell carcinoma
Farhangdoost, N.; Horth, C.; Hu, B.; Bareke, E.; Chen, X.; Li, Y.; Coradin, M.; Garcia, B. A.; Lu, C.; Majewski, J.
10.1101/2020.05.30.124057 — genomics — Posted on 2020-08-22
1431 Early life nociception is influenced by peripheral growth hormone signaling
Dourson, A. J.; Ford, Z. K.; Green, K. J.; McCrossan, C. E.; Hofmann, M. C.; Hudgins, R. C.; Jankowski, M. P.
10.1101/2020.07.16.206904 — neuroscience — Posted on 2020-08-22
1432 In vivo assessment of mechanisms underlying the neurovascular basis of postictal amnesia
Farrell, J. S.; Colangeli, R.; Dudok, B.; Wolff, M. D.; Nguyen, S. L.; Jackson, J.; Dickson, C. T.; Soltesz, I.; Teskey, G. C.
10.1101/2020.01.30.926717 — neuroscience — Posted on 2020-08-22
1433 Targeted knockdown of ribulose-1, 5-bisphosphate carboxylase-oxygenase in rice mesophyll cells impact on photosynthesis and growth
Maheshwari, C.; Coe, R. A.; KARKI, S.; Covshoff, S.; Tapia, R.; Tyagi, A.; Hibberd, J. M.; Furbank, R. T.; Quick, W. P.; Lin, H.-C.
10.1101/2020.08.20.259382 — plant biology — Posted on 2020-08-22
1436 Sarcoptic mange; an emerging threat to Chilean wild mammals?
Montecino-Latorre, D.; Napolitano, C.; Briceno, C.; Uhart, M.
10.1101/2020.03.02.974188 — ecology — Posted on 2020-08-22
1438 Developmental constraints modulate reproductive fate and plasticity within the Arabidopsis ovule primordium
Hernandez-Lagana, E.; Mosca, G.; Mendocilla Sato, E.; Pires, N.; Frey, A.; Giraldo-Fonseca, A.; Grossniklaus, U.; Hamant, O.; Godin, C.; Boudaoud, A.; Grimanelli, D.; Autran, D.; Baroux, C.
10.1101/2020.07.30.226670 — plant biology — Posted on 2020-08-22
1440 Tumor IsomiR Encyclopedia (TIE): a pan-cancer database of miRNA isoforms
Bofill-De Ros, X.; Luke, B.; Guthridge, R.; Mudunuri, U.; Loss, M.; Gu, S.
10.1101/2020.08.20.259713 — genomics — Posted on 2020-08-22
1442 Towards Reproducible Brain-Wide Association Studies
Marek, S.; Tervo-Clemmens, B.; Calabro, F. J.; Montez, D. F.; Kay, B. P.; Hatoum, A. S.; Donohue, M. R.; Foran, W.; Miller, R. L.; Feczko, E.; Miranda Dominguez, O.; Graham, A.; Earl, E. A.; Perrone, A.; Cordova, M.; Doyle, O.; Moore, L. A.; Conan, G.; Uriarte, J.; Snider, K.; Tam, A.; Chen, J.; Newbold, D. J.; Zheng, A.; Seider, N. A.; Van, A. N.; Laumann, T. O.; Thompson, W. K.; Greene, D. J.; Petersen, S. E.; Nichols, T.; Yeo, B. T. T.; Barch, D. M.; Garavan, H.; Luna, B.; Fair, D. A.; Dosenbach, N. U. F.
10.1101/2020.08.21.257758 — neuroscience — Posted on 2020-08-22
1444 Mass Spectrometry Imaging of N-Glycans Reveals Racial Discrepancies in Low Grade Prostate Tumors
Conroy, L. R.; Young, L. E.; Stanback, A. E.; Austin, G. L.; Liu, J.; Liu, J.; Allison, D. B.; Sun, R. C.
10.1101/2020.08.20.260026 — cancer biology — Posted on 2020-08-22
1445 Convergent mutations in tissue-specific regulatory regions reveal novel cancer drivers
Sinnott-Armstrong, N.; Seoane, J. A.; Pritchard, J. K.; Curtis, C.; Snyder, M. P.
10.1101/2020.08.21.239954 — cancer biology — Posted on 2020-08-22
1448 Intronic enhancers regulate the expression of genes involved in tissue-specific functions and homeostasis
Borsari, B.; Villegas-Miron, P.; Laayouni, H.; Segarra-Casas, A.; Bertranpetit, J.; Guigo, R.; Acosta, S.
10.1101/2020.08.21.260836 — genomics — Posted on 2020-08-22
1449 Wt1-expressing cells contribute to mesoderm-derived tissues in intestine and mesentery in two distinct phases during murine embryonic development.
Alghamdi, S.; Wilm, T. P.; Beglinger, S.; Boyes, M.; Tanton, H.; Mutter, F.; Allardyce, J.; Foisor, V.; Middlehurst, B.; Carr, L.; Ward, K.; Benameur, T.; Butts, T.; Hastie, N.; Wilm, B.
10.1101/2020.08.21.257154 — developmental biology — Posted on 2020-08-21
1451 Characterization of Viral Insulins Reveals White Adipose Tissue Specific Effects in Mice
Chrudinova, M.; Moreau, F.; Noh, H. L.; Panikova, T.; Zakova, L.; Friedline, R. H.; Valenzuela, F. A.; Kim, J. K.; Jiracek, J.; Kahn, C. R.; Altindis, E.
10.1101/2020.08.21.261321 — cell biology — Posted on 2020-08-22
1452 An Acentriolar Centrosome At The C. elegans Ciliary Base
Garbrecht, J.; Laos, T.; Holzer, E.; Dillinger, M.; Dammermann, A.
10.1101/2020.08.21.260547 — cell biology — Posted on 2020-08-22
1456 Astrocytic Neurexin-1 Orchestrates Functional Synapse Assembly
Trotter, J. H.; Dargaei, Z.; Wohr, M.; Liakath-Ali, K.; Raju, K.; Essayan-Perez, S.; Nabet, A.; Liu, X.; Sudhof, T.
10.1101/2020.08.21.262097 — neuroscience — Posted on 2020-08-21
1461 Activation of Notch1 drives the development of radiation-induced thymic lymphoma in p53 wild-type mice
Lee, C.-L.; Brock, K. D.; Hasapis, S.; Zhang, D.; Sibley, A. B.; Qin, X.; Gresham, J.; Caraballo, I.; Luo, L.; Daniel, A. R.; Hilton, M. J.; Owzar, K.; Kirsch, D. G.
10.1101/2020.08.21.261487 — cancer biology — Posted on 2020-08-21
1462 SOX11 is a lineage-dependency factor and master epigenetic regulator in neuroblastoma
Decaesteker, B.; Louwagie, A.; Loontiens, S.; De Vloed, F.; Roels, J.; Vanhauwaert, S.; De Brouwer, S.; Sanders, E.; Denecker, G.; D'haene, E.; Van Haver, S.; Van Loocke, W.; Van Dorpe, J.; Creytens, D.; Van Roy, N.; Pieters, T.; Van Neste, C.; Fischer, M.; Van Vlierberghe, P.; Roberts, S. S.; Schulte, J.; Ek, S.; Versteeg, R.; Koster, J.; van Nes, J.; De Preter, K.; Speleman, F.
10.1101/2020.08.21.261131 — cancer biology — Posted on 2020-08-21
1465 Pleiotropy and Epistasis Within and Between Signaling Pathways Defines the Genetic Architecture of Fungal Virulence
Roth, C. J. N.; Murray, D.; Scott, A.; Fu, C.; Averette, A. F.; Sun, S.; Heitman, J.; Magwene, P. M.
10.1101/2020.08.21.259861 — genetics — Posted on 2020-08-21
1467 The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish
Veloso, A.; Bleuart, A.; Orban, T.; Bruyr, J.; Cabochette, P.; Germano, R. F.; Bernard, A.; Vanhollebeke, B.; Martin, M.; Dequiedt, F.
10.1101/2020.08.20.259663 — developmental biology — Posted on 2020-08-21
1468 Oviduct epithelial cells constitute two developmentally distinct lineages that are spatially separated along the distal-proximal axis
Ford, M. J.; Harwalkar, K.; Pacis, A. S.; Maunsell, H.; Wang, Y. C.; Badescu, D.; Teng, K.; Yamanaka, N.; Bouchard, M.; Ragoussis, I.; Yamanaka, Y.
10.1101/2020.08.21.261016 — developmental biology — Posted on 2020-08-21
1470 The early evolution of oral poliovirus vaccine is shaped by strong positive selection and tight transmission bottlenecks
Valesano, A. L.; Taniuchi, M.; Fitzsimmons, W. J.; Islam, M. O.; Ahmed, T.; Zaman, K.; Haque, R.; Wong, W.; Famulare, M.; Lauring, A. S.
10.1101/2020.08.20.260075 — microbiology — Posted on 2020-08-21
1471 Development and validation of an assay for detection of Japanese Encephalitis virus specific antibody responses
Pushpakumara, P. D.; Jeewandara, C.; Gomes, L.; Perera, Y.; Wijewickrama, A.; Malavige, G. N.; Goonesekara, C.
10.1101/2020.08.21.260646 — immunology — Posted on 2020-08-21
1472 A Noninvasive Approach to Optogenetics Using Focused Ultrasound Blood Brain Barrier Disruption for the Delivery of Radioluminescent Particles
Rich, M. C.; Zhang, E.; Dickey, A.; Jones, H. W.; Cannon, K. E.; Bandera, Y.; Foulger, S. H.; Lubin, F. D.; Bolding, M. S.
10.1101/2020.08.20.248302 — neuroscience — Posted on 2020-08-21
1473 Maladaptive myelination promotes epileptogenesis in absence epilepsy
Knowles, J. K.; Soane, C.; Frost, E.; Tam, L. T.; Fraga, D.; Xu, H.; Batra, A.; Ni, L.; Villar, K.; Saucedo, T.; Huguenard, J.; Monje, M.
10.1101/2020.08.20.260083 — neuroscience — Posted on 2020-08-21
1474 Increased and synchronous recruitment of release sites underlies hippocampal mossy fiber presynaptic potentiation
Orlando, M.; Dvorzhak, A.; Bruentgens, F.; Maglione, M.; Rost, B. R.; Sigrist, S. J.; Breustedt, J. M.; Schmitz, D.
10.1101/2020.08.21.260638 — neuroscience — Posted on 2020-08-21
1479 Routine sub-2.5 A cryo-EM structure determination of B-family G protein-coupled receptors
Danev, R.; Belousoff, M.; Liang, Y.-L.; Zhang, X.; Wootten, D.; Sexton, P. M.
10.1101/2020.08.21.260851 — biophysics — Posted on 2020-08-21
1480 Inoculum effect of antimicrobial peptides
Loffredo, M. R.; Savini, F.; Bobone, S.; Casciaro, B.; Franzyk, H.; Mangoni, M. L.; Stella, L.
10.1101/2020.08.21.260620 — biophysics — Posted on 2020-08-21
1482 A simple, high-throughput method of protein and label removal from extracellular vesicle samples
Welsh, J. A.; Killingswroth, B.; Kepley, J.; Traynor, T.; McKinnon, K.; Savage, J.; Appel, D.; Aldape, K.; Camphausen, K.; Berzofsky, J. A.; Ivanov, A. R.; Ghiran, I. H.; Jones, J. C.
10.1101/2020.08.20.260307 — biochemistry — Posted on 2020-08-21
1483 Phase separation by the Sterile Alpha Motif of Polyhomeotic compartmentalizes Polycomb Group proteins and enhances their activity
Seif, E.; Kang, J. J.; Sasseville, C.; Senkovitch, O.; Kaltashov, A.; Boulier, E. L.; Kapur, I.; Kim, C. A.; Francis, N.
10.1101/2020.08.20.259994 — biochemistry — Posted on 2020-08-21
1485 Feasibility and promise of circulating tumor DNA analysis in dogs with naturally-occurring sarcoma.
Favaro, P. F.; Stewart, S. D.; McDonald, B. R.; Cawley, J.; Contente-Cuomo, T.; Wong, S.; Hendricks, W. P.; Trent, J. M.; Khanna, C.; Murtaza, M.
10.1101/2020.08.20.260349 — genomics — Posted on 2020-08-21
1489 Path tortuosity changes the transport cost paradigm in terrestrial animals
Wilson, R.; Rose, K. A.; Metcalfe, R. S.; Holton, M.; Redcliffe, J.; Gunner, R.; Borger, L.; Loison, A.; Milos, J.; Painter, M. S.; Silovsky, V.; Marks, N.; Garel, M.; Toigo, C.; Marchand, P.; Bennett, N. C.; McNarry, M. A.; Mackintosh, K. A.; Brown, R.; Scantlebury, M.
10.1101/2020.08.20.259390 — ecology — Posted on 2020-08-21
1490 DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A
Leon, K. E.; Buj, R.; Lesko, E.; Dahl, E. S.; Chen, C.-W.; Imamura Kawasawa, Y.; Kossenkov, A. V.; Hobbs, R. P.; Aird, K. M.
10.1101/2020.08.21.258020 — cell biology — Posted on 2020-08-21
1494 Selective dephosphorylation by PP2A-B55 directs the meiosis I - meiosis II transition in oocytes
Swartz, S. Z.; Nguyen, H. T.; McEwan, B. C.; Adamo, M. E.; Cheeseman, I. M.; Kettenbach, A. N.
10.1101/2020.08.21.260216 — cell biology — Posted on 2020-08-21
1495 Re-emergence of BTV serotype 4 in North Macedonia, July 2020
Flannery, J.; King, S.; Rajko-Nenow, P.; Popova, Z.; Krstevski, K.; Djadjovski, I.; Batten, C.
10.1101/2020.08.20.259457 — molecular biology — Posted on 2020-08-21
1496 Analysis of the oxidative stress regulon identifies soxS as a genetic target for resistance reversal in multi-drug resistant Klebsiella pneumoniae
Anes, J.; Dever, K.; Eshwar, A.; Nguyen, S.; Cao, Y.; Sivasankaran, S. K.; Sakalauskaite, S.; Lehner, A.; Devineau, S.; Daugelavicius, R.; Fanning, S.; Srikumar, S.
10.1101/2020.08.21.262022 — microbiology — Posted on 2020-08-21
1497 Methanotrophic Community Detected by DNA-SIP at Bertioga Mangrove Area, Southeast Brazil
Linhares, D. C.; Saia, F. T.; Duarte, R. T. D.; Nakayama, C. R.; de Melo, I. S.; Pellizari, V. H.
10.1101/2020.08.20.255125 — microbiology — Posted on 2020-08-21
1498 A mating-induced reproductive gene promotes Anopheles tolerance to Plasmodium falciparum infection
Marcenac, P.; Shaw, W. R.; Kakani, E. G.; Mitchell, S. N.; South, A.; Werling, K.; Marrogi, E.; Abernathy, D. G.; Yerbanga, R. S.; Dabire, R. K.; Diabate, A.; Lefevre, T.; Catteruccia, F.
10.1101/2020.08.20.260125 — microbiology — Posted on 2020-08-21
1499 Bark from avocado trees of different geographic locations have consistent microbial communities
Aguirre-von-Wobeser, E.; Alonso-Sanchez, A.; Mendez-Bravo, A.; Villanueva Espino, L. A.; Reverchon, F.
10.1101/2020.08.21.261396 — microbiology — Posted on 2020-08-21
1500 Bacillus endospore appendages form a novel family of disulfide-linked pili
Pradhan, B.; Liedtke, J.; Sleuel, M.; Lindback, T.; Llarena, A.-K.; Brynildsrud, O.; Aspholm, M.; Remaut, H.
10.1101/2020.08.21.260141 — microbiology — Posted on 2020-08-21
1501 Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase
Cai, Y.; Jaecklein, E.; Mackenzie, J.; Papavinasasundaram, K.; Olive, A. J.; Chen, X.; Steyn, A. J. C.; Sassetti, C. M.
10.1101/2020.08.21.260737 — microbiology — Posted on 2020-08-21
1502 Circuit reorganization in the Drosophila mushroom body calyx accompanies memory consolidation
Baltruschat, L. G.; Ranft, P.; Prisco, L.; Lauritzen, J. S.; Fiala, A.; Bock, D.; Tavosanis, G.
10.1101/2020.08.20.259135 — neuroscience — Posted on 2020-08-21
1503 Optogenetic activation of nonhuman primate cortical and subcortical brain circuits highlights detection capabilities of MEG source imaging
Alberto, G. E.; Stapleton-Kotloski, J. R.; Klorig, D. J.; Rogers, E. R.; Constantinidis, C. E.; Daunais, J.; Godwin, D. W.
10.1101/2020.08.20.259465 — neuroscience — Posted on 2020-08-21
1504 Naphthalene monoimide derivative ameliorates amyloid burden and cognitive decline in a transgenic mouse model of Alzheimer's disease
Govindaraju, T.; Samanta, S.; Rajasekhar, K.; Ramesh, M.; Murugan, N. A.; Alam, S.; Shah, D.; Clement, J. P.
10.1101/2020.08.20.260166 — neuroscience — Posted on 2020-08-21
1505 Title: Potentially zoonotic gastrointestinal nematodes co-infecting free ranging non-human primates in Kenyan urban centres
Mbuthia, P.; Murungi, E.; Owino, V.; Akinyi, M.; Eastwood, G.; Nyamota, R.; Lekolool, I.; Jeneby, M.
10.1101/2020.08.19.254714 — zoology — Posted on 2020-08-21
1512 4 β-hydroxycholesterol is a pro-lipogenic factor that promotes SREBP1c expression and activity through Liver X-receptor.
Moldavski, O.; Zushin, P.-J. H.; Berdan, C. A.; van Eijkeren, R. J.; Jiang, X.; Qian, M.; Ory, D. S.; Covey, D. F.; Nomura, D.; Stahl, A.; Weiss, E.; Zoncu, R.
10.1101/2020.08.20.256487 — biochemistry — Posted on 2020-08-21
1515 Stable isotope informed genome-resolved metagenomics uncovers potential trophic interactions in rhizosphere soil
Starr, E. P.; Shi, S.; Blazewicz, S. J.; Koch, B. J.; Probst, A. J.; Hungate, B. A.; Pett-Ridge, J.; Firestone, M. K.; Banfield, J. F.
10.1101/2020.08.21.262063 — microbiology — Posted on 2020-08-21
1517 Exploiting oxalotrophic bacteria to control Aspergillus niger lung infections
Palmieri, F.; Palmieri, I.; Noormamode, N.; Estoppey, A.; Ishak, M. O.; Kelliher, J. M.; Vallat, A.; Iyer, R.; Bindschedler, S.; Davenport, K.; Chain, P. S. G.; Harris, J. F.; Junier, P.
10.1101/2020.08.20.259929 — microbiology — Posted on 2020-08-21
1518 Limited window for donation of convalescent plasma with high live-virus neutralizing antibodies for COVID-19 immunotherapy
Gontu, A.; Srinivasan, S.; Salazar, E.; Surendran Nair, M.; Nissly, R. H.; Greenawalt, D.; Bird, I. M.; Herzog, C.; Ferrari, M. J.; Poojary, I.; Katani, R.; Lindner, S. E.; Minns, A. M.; Rossi, R.; Christensen, P. A.; Castillo, B.; Chen, J.; Eagar, T. N.; Yi, X.; Zhao, P.; Leveque, C.; Olsen, R. J.; Bernard, D. W.; Gollihar, J.; Musser, J. M.; Kapur, V.; Kuchipudi, S. V.
10.1101/2020.08.21.261909 — immunology — Posted on 2020-08-21
1520 Iota carrageenan and xylitol inhibit SARS-CoV-2 in Vero cell culture
Vega, J. C.; Bansal, S.; Jonsson, C. B.; Taylor, S. L.; Figueroa, J. M.; Dugour, A. V.; Palacios, C.
10.1101/2020.08.19.225854 — pharmacology and toxicology — Posted on 2020-08-21
1522 Astodrimer sodium, dendrimer antiviral, inhibits replication of SARS-CoV-2 in vitro
Paull, J. R. A.; Castellarnau, A.; Luscombe, C. A.; Fairley, J. K.; Heery, G. P.
10.1101/2020.08.20.260190 — microbiology — Posted on 2020-08-21
1525 Characterization of cells susceptible to SARS-COV-2 and methods for detection of neutralizing antibody by focus forming assay
Stone, E. T.; Geerling, E.; Steffen, T. L.; Hassert, M.; Dickson, A.; Spencer, J. F.; Toth, K.; DiPaolo, R. J.; Brien, J. D.; Pinto, A. K.
10.1101/2020.08.20.259838 — pathology — Posted on 2020-08-21
1530 Targeting pentose phosphate pathway for SARS-CoV-2 therapy
Bojkova, D.; Costa, R.; Bechtel, M.; Ciesek, S.; Michaelis, M.; Cinatl, J.
10.1101/2020.08.19.257022 — microbiology — Posted on 2020-08-21
1531 Local Glutamate-Mediated Dendritic Plateau Potentials Change the State of the Cortical Pyramidal Neuron
Gao, P. P.; Graham, J. W.; Zhou, W.-L.; Jang, J.; Angulo, S.; Dura-Bernal, S.; Hines, M.; Lytton, W. W.; Antic, S. D.
10.1101/828582 — neuroscience — Posted on 2020-08-21
1532 SARS-CoV-2 infects brain choroid plexus and disrupts the blood-CSF-barrier
Pellegrini, L.; Albecka, A.; Mallery, D. L.; Kellner, M. J.; Paul, D.; Carter, A. P.; James, L. C.; Lancaster, M. A.
10.1101/2020.08.20.259937 — neuroscience — Posted on 2020-08-21
1537 A computationally designed fluorescent biosensor for D-serine
Vongsouthi, V.; Whitfield, J. H.; Unichenko, P.; Mitchell, J. A.; Breithausen, B.; Khersonsky, O.; Kremers, L.; Janovjak, H.; Monai, H.; Hirase, H.; Fleishman, S. J.; Henneberger, C.; Jackson, C. J.
10.1101/2020.08.18.255380 — biochemistry — Posted on 2020-08-21
1538 Patterning the embryonic pulmonary mesenchyme
Goodwin, K.; Jaslove, J. M.; Tao, H.; Zhu, M.; Hopyan, S.; Nelson, C. M.
10.1101/2020.08.20.259101 — developmental biology — Posted on 2020-08-21
1539 A rapid and efficient screening system for neutralizing antibodies and its application for the discovery of potent neutralizing antibodies to SARS-CoV-2 S-RBD
Han, X.; Wang, Y.; Li, S.; Hu, C.; Li, T.; Gu, C.; Wang, K.; Shen, M.; Wang, J.; Hu, J.; Wu, R.; Mu, S.; Gong, F.; Chen, Q.; Gao, F.; Huang, J.; Long, Y.; Luo, F.; Song, S.; Long, S.; Hao, Y.; Li, L.; Wu, Y.; Xu, W.; Cai, X.; Gao, Q.; Zhang, G.; He, C.; Deng, K.; Du, L.; Nai, Y.; Wang, W.; Xie, Y.; Qu, D.; Huang, A.; Tang, N.; Jin, A.
10.1101/2020.08.19.253369 — immunology — Posted on 2020-08-21
1541 Global prevalence of potentially pathogenic short-tandem repeats in an epilepsy cohort
Moreau, C.; Michaud, J. L.; Hamdan, F. F.; Bouchard, J.; Tremblay, V.; Rouleau, G. A.; Minassian, B. A.; Cossette, P.; Girard, S. L.
10.1101/2020.08.20.259168 — genetics — Posted on 2020-08-21
1544 Single cell RNA sequence analysis of human bone marrow samples reveals new targets for isolation of skeletal stem cells using DNA-coated gold nanoparticles
Matthews, E.; Lanham, S.; White, K.; Kyriazi, M.-E.; Alexaki, K.; El-Sagheer, A.; Brown, T.; Kanaras, A.; West, J.; MacArthur, B. D.; Stumpf, P. S.; Oreffo, R. O. C.
10.1101/2020.06.17.156836 — cell biology — Posted on 2020-08-21
1547 Object manifold geometry across the mouse cortical visual hierarchy
Froudarakis, E.; Cohen, U.; Diamantaki, M.; Walker, E. Y.; Reimer, J.; Berens, P.; Sompolinsky, H.; Tolias, A. S.
10.1101/2020.08.20.258798 — neuroscience — Posted on 2020-08-21
1552 Forces experienced by instrumented animals depend on lifestyle
Wilson, R. P.; Rose, K. A.; Gunner, R.; Holton, M.; Marks, N.; Bennett, N. C.; Bell, S.; Twining, J.; Hesketh, J.; Duarte, C. M.; Bezodis, N.; Scantlebury, M.
10.1101/2020.08.20.258756 — ecology — Posted on 2020-08-21
1556 CD300lf conditional knockout mouse reveals strain-specific cellular tropism for murine norovirus
Graziano, V. R.; Alfajaro, M. M.; Schmitz, C.; Filler, R. B.; Strine, M. S.; Wei, J.; Hsieh, L. L.; Baldridge, M. T.; Nice, T. J.; Lee, S.; Orchard, R. C.; Wilen, C. B.
10.1101/2020.08.19.258467 — microbiology — Posted on 2020-08-21
1561 Structural basis for the activation of CDK7 by MAT1 and Cyclin H
Peissert, S.; Schlosser, A.; Kendel, R.; Kuper, J.; Kisker, C.
10.1101/2020.08.20.258632 — biochemistry — Posted on 2020-08-21
1563 Characterization of Brain-Derived Extracellular Vesicle Lipids in Alzheimer's Disease
Su, H.; Rustam, Y. H.; Masters, C. L.; Makalic, E.; McLean, C.; Hill, A.; Barnham, K. J.; Reid, G. E.; Vella, L. J.
10.1101/2020.08.20.260356 — molecular biology — Posted on 2020-08-21
1565 CAR Macrophages for SARS-CoV-2 Immunotherapy
Fu, W.; Lei, C.; Qian, K.; Ma, Z.; Li, T.; Zhang, W.; Lin, F.; Zhao, J.; Hu, S.
10.1101/2020.07.26.222208 — bioengineering — Posted on 2020-08-21
1572 Intrinsically disordered protein ensembles shape evolutionary rates revealing conformational patterns
Palopoli, N.; Marchetti, J.; Monzon, A. M.; Zea, D. J.; Tosatto, S. C. E.; Fornasari, M. S.; Parisi, G.
10.1101/2020.07.29.227363 — bioinformatics — Posted on 2020-08-21
1575 The TAT Protein Transduction Domain as an Intra-articular Drug-Delivery Technology
Mailhiot, S. E.; Thompson, M. A.; Eguchi, A.; Dinkel, S.; Lotz, M. K.; Dowdy, S. F.; June, R. K.
10.1101/2020.04.28.066902 — bioengineering — Posted on 2020-08-21
1576 Genetics of mouse Tas1r3-independent sucrose intake
Lin, C.; Tordoff, M. G.; Li, X.; Bosak, N.; Ishiwatari, Y.; Inoue, M.; Beauchamp, G. K.; Bachmanov, A. A.; Reed, D. R.
10.1101/379347 — animal behavior and cognition — Posted on 2020-08-21
1581 Large male proboscis monkeys have larger noses but smaller canines
Matsuda, I.; Stark, D. J.; Saldivar, D. A. R.; Tuuga, A.; Nathan, S. K. S. S.; Goossens, B.; van Schaik, C. P.; Koda, H.
10.1101/848515 — evolutionary biology — Posted on 2020-08-21
1582 Assessing the impact of the threatened crucian carp (Carassius carassius) on pond invertebrate diversity - a comparison of conventional and molecular tools
Harper, L. R.; Lawson Handley, L.; Sayer, C. D.; Read, D. S.; Benucci, M.; Blackman, R. C.; Hill, M. J.; Hänfling, B.
10.1101/2020.03.30.015677 — ecology — Posted on 2020-08-21
1583 Live imaging of reporter zebrafish reveals dynamics and molecular basis of physiological-stress induced mitophagy.
Wrighton, P. J.; Shwartz, A.; Heo, J.-M.; Quenzer, E. D.; LaBella, K. A.; Harper, J. W.; Goessling, W.
10.1101/2020.03.26.010405 — cell biology — Posted on 2020-08-21
1584 Full-length 16S rRNA gene amplicon analysis of human gut microbiota using MinION™ nanopore sequencing confers species-level resolution
Matsuo, Y.; Komiya, S.; Yasumizu, Y.; Yasuoka, Y.; Mizushima, K.; Takagi, T.; Kryukov, K.; Fukuda, A.; Morimoto, Y.; Naito, Y.; Okada, H.; Bono, H.; Nakagawa, S.; Hirota, K.
10.1101/2020.05.06.078147 — microbiology — Posted on 2020-08-20
1585 Modulation of macrophage inflammatory function through selective inhibition of the epigenetic reader protein SP140
Ghiboub, M.; Koster, J.; Craggs, P. D.; Li Yim, A. Y. F.; Shillings, A.; Hutchinson, S.; Bingham, R. P.; Gatfield, K.; Hageman, I. L.; Yao, G.; O'Keefe, H. P.; Coffin, A.; Patel, A.; Sloan, L. A.; Mitchell, D. J.; Lunven, L.; Watson, R. J.; Blunt, C. E.; Harrison, L. A.; Bruton, G.; Kumar, U.; Hamer, N.; Spaull, J. R.; Zwijnenburg, D. A.; Welting, O.; Hakvoort, T. B. M.; van Limbergen, J.; Henneman, P.; Prinjha, R. K.; de Winther, M. P.; Harker, N. R.; Tough, D. F.; de Jonge, W. J.
10.1101/2020.08.10.239475 — immunology — Posted on 2020-08-20
1586 Equine hyperimmune globulin raised against the SARS-CoV-2 spike glycoprotein has extremely high neutralizing titers
Cunha, L. E. R.; Stolet, A. A.; Strauch, M. A.; Pereira, V. A. R.; Dumard, C. H.; Souza, P. N. C.; Fonseca, J. G.; Pontes, F. E.; Meirelles, L. G. R.; Albuquerque, J. W. M.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Lima, T. M.; Alvim, R. G. F.; Zingali, R.; Oliveira, G. A. P.; Souza, T. M. L.; TANURI, A.; Gomes, A. M. O.; Oliveira, A. C.; Guedes, H. L. M.; Castilho, L. R.; Silva, J. L.
10.1101/2020.08.17.254375 — immunology — Posted on 2020-08-21
1588 Eliminating accidental deviations to minimize generalization error: applications in connectomics and genomics
Bridgeford, E. W.; Wang, S.; Yang, Z.; Wang, Z.; Xu, T.; Craddock, C.; Dey, J.; Kiar, G.; Gray-Roncal, W.; Coulantoni, C.; Douville, C.; Priebe, C. E.; Caffo, B.; Milham, M.; Zuo, X.-N.; Consortium for Reliability and Reproducibility, ; Vogelstein, J. T.
10.1101/802629 — neuroscience — Posted on 2020-08-20
1590 The effect of acute sleep deprivation on skeletal muscle protein synthesis and the hormonal environment
Lamon, S.; Morabito, A.; Arentson-Lantz, E. J.; Knowles, O.; Vincent, G. E.; Condo, D.; Alexander, S. E.; Garnham, A.; Paddon-Jones, D. J.; Aisbett, B.
10.1101/2020.03.09.984666 — physiology — Posted on 2020-08-20
1591 Female mice exposed to low-doses of dioxin during pregnancy and lactation have increased susceptibility to diet-induced obesity and diabetes
Hoyeck, M. P.; Merhi, R. C.; Blair, H.; Spencer, C. D.; Payant, M. A.; Martin Alfonso, D. I.; Zhang, M.; Matteo, G.; Chee, M. J.; Bruin, J. E.
10.1101/2020.07.09.195552 — pharmacology and toxicology — Posted on 2020-08-20
1593 A systematic comparison of chloroplast genomeassembly tools
Freudenthal, J. A.; Pfaff, S.; Terhoeven, N.; Korte, A.; Ankenbrand, M. J.; Foerster, F.
10.1101/665869 — bioinformatics — Posted on 2020-08-20
1596 A robust and versatile nanobody platform for drug delivery
Shen, Z.; Xiang, Y.; Vergara, S.; Chen, A.; Xiao, Z.; Santiago, U.; Jin, C.; Sang, Z.; Luo, J.; Chen, K.; Schneidman-Duhovny, D.; Camacho, C. J.; Calero, G.; Hu, B.; Shi, Y.
10.1101/2020.08.19.257725 — bioengineering — Posted on 2020-08-20
1598 A rapid and simple method for assessing and representing genome sequences relatedness
Briand, M.; Bouzid, M.; Hunault, G.; Legeay, M.; Fischer-Le Saux, M.; Barret, M.
10.1101/569640 — genomics — Posted on 2020-08-20
1599 Circulating adiponectin mediates the association between omentin gene polymorphism and cardiometabolic health in Asian Indians
Vimaleswaran, K. S.; Jiang, J.; Dhanasekaran, B.; Ramya, K.; Mohan, D.; Coimbatore Subramanian, S. R.; Lakshmipriya, N.; Vasudevan, S.; Rajendra, P.; Ranjit Mohan, A.; Viswanathan, M.; Venkatesan, R.
10.1101/2020.08.20.258897 — genetics — Posted on 2020-08-20
1600 Hearing impairment due to Mir183/96/182 mutations suggests both loss and gain of function effects
Lewis, M. A.; Di Domenico, F.; Ingham, N. J.; Prosser, H. M.; Steel, K. P.
10.1101/579003 — genetics — Posted on 2020-08-20
1601 Polygenic Scores for Cognitive Abilities and their Association with Different Aspects of General Intelligence - a Deep Phenotyping Approach
Genc, E.; Schlüter, C.; Fraenz, C.; Arning, L.; Nguyen, H. P.; Voelkle, M. C.; Streit, F.; Güntürkün, O.; Kumsta, R.; Ocklenburg, S.
10.1101/2020.06.03.131318 — genetics — Posted on 2020-08-20
1605 eDNA metabarcoding as a biomonitoring tool for marine protected areas
Gold, Z. J.; Sprague, J.; Kushner, D. J.; Zerecero, E.; Barber, P. H.
10.1101/2020.08.20.258889 — molecular biology — Posted on 2020-08-20
1607 Elucidation of the signatures of proteasome-catalysed peptide splicing
Paes, W.; Leonov, G.; Partridge, T.; Nicastri, A.; Ternette, N.; Borrow, P.
10.1101/2020.04.05.025908 — immunology — Posted on 2020-08-20
1612 Regional expression profiles of risk genes for depression are associated with brain activation patterns in emotion and reward tasks
Komorowski, A.; Vidal, R.; Singh, A.; Murgas, M.; Pena-Centeno, T.; Gryglewski, G.; Kasper, S.; Wiltfang, J.; Lanzenberger, R.; Goya-Maldonado, R.
10.1101/2020.06.27.175257 — neuroscience — Posted on 2020-08-20
1614 Eurycomanone regulates lipid metabolism by activating the cAMP/PKA pathway
zhihui, J.; Han, H.; Li, S.; Tian, J.; Gao, Z.; Huang, W.; Zhang, D.; Ouyang, H.; Feng, Y.
10.1101/2020.08.20.258855 — pharmacology and toxicology — Posted on 2020-08-20
1615 Conformational dynamics of photosynthetic Light-Harvesting Complex II in a native membrane environment
Azadi-Chegeni, F.; Ward, M. E.; Perin, G.; Simionato, D.; Morosinotto, T.; Baldus, M.; Pandit, A.
10.1101/288860 — biophysics — Posted on 2020-08-20
1616 Segmentation boosting with compensation methods in optical coherence tomography angiography images
Lee, Y.-C.; Ding, J.-J.; Yeung, L.; Lee, T.-W.; Chang, C.-J.; Lin, Y.-T.; Chang, R. Y.
10.1101/2020.08.20.258905 — bioengineering — Posted on 2020-08-20
1618 Maternal factor PABPN1L is essential for maternal mRNA degradation during maternal-to-zygotic transition
Wang, Y.; Feng, T.; Shi, X.; Liu, S.; Wang, Z.; Zhang, X.; Zhang, J.; Zhao, S.; Zhang, J.; Ling, X.; Liu, M.
10.1101/2020.08.20.258830 — genetics — Posted on 2020-08-20
1619 Single cell tracking based on Voronoi partition via stable matching
Chang, Y. H.; Linsley, J. W.; Lamstein, J.; Kalra, J.; Epstein, I.; Barch, M.; Daily, K.; Snyder, P.; Omberg, L.; Heiser, L.; Finkbeiner, S.
10.1101/2020.08.20.259408 — systems biology — Posted on 2020-08-20
1620 Targeted knockdown of ribulose-1, 5-bisphosphate carboxylase-oxygenase in rice mesophyll cells impact on photosynthesis and growth
Lin, H.-C.; Maheshwari, C.; Coe, R. A.; KARKI, S.; Covshoff, S.; Tapia, R.; Tyagi, A.; Hibberd, J. M.; Furbank, R. T.; Quick, P.
10.1101/2020.08.20.259382 — plant biology — Posted on 2020-08-20
1621 Primary carbohydrate metabolism genes participate in heat stress memory at the shoot apical meristem of Arabidopsis thaliana
Olas, J. J.; Apelt, F.; Annunziata, M. G.; Richard, S. I.; Gupta, S.; Kragler, F.; Balazadeh, S.; Mueller-Roeber, B.
10.1101/2020.08.20.258939 — plant biology — Posted on 2020-08-20
1622 Discovery and 3D imaging of a novel {triangleup}Np63-expressing basal cell type in human pancreatic ducts with implications in disease
Martens, S.; Van Bulck, M.; Coolens, K.; Madhloum, H.; Esni, F.; Leuckx, G.; Heimberg, H.; Bouwens, L.; Jacquemin, P.; in't Veld, P.; Lefesvre, P.; Real, F. X.; Rovira, M.; Rooman, I.
10.1101/2020.08.20.259317 — pathology — Posted on 2020-08-20
1623 Enterococcus peptidoglycan remodeling promotes immune checkpoint inhibitor therapy
Griffin, M. E.; Espinosa, J.; Becker, J. L.; Jha, J. K.; Fanger, G. R.; Hang, H. C.
10.1101/2020.08.20.256263 — cancer biology — Posted on 2020-08-20
1625 Chloride-dependent conformational changes in the GlyT1 glycine transporter
Zhang, Y.-W.; Uchendu, S.; Leone, V.; Bradshaw, R. T.; Sangwa, N.; Forrest, L.; Rudnick, G.
10.1101/2020.08.20.259572 — biochemistry — Posted on 2020-08-20
1626 Context-dependent behavioral plasticity compromises disruptive selection on sperm traits in squid
Hirohashi, N.; Sato, N.; Iwata, Y.; Tomano, S.; Nur E Alam, M.; Escolar, O.; Angel Fernandez-Alvarez, F.; Villanueva, R.; Haselmann Apostolico, L.; Amoroso Rodriguez Marian, J. E.
10.1101/2020.08.20.258988 — evolutionary biology — Posted on 2020-08-20
1629 LINE-1 ORF1p RIP-seq reveals widespread association with p-body enriched mRNAs
Briggs, E. M.; McKerrow, W.; Mita, P.; Boeke, J. D.; Logan, S. K.; Fenyö, D.
10.1101/2020.08.20.259424 — cell biology — Posted on 2020-08-20
1631 Characterization of novel pollen-expressed transcripts reveals their potential roles in pollen heat stress response in Arabidopsis thaliana.
Miller, G.; Rutley, N.; Doniger, T.; Poidevin, L.; Ferrando, A.; Forment, J.; Luria, G.; Harper, J. F.; Tillet, R. L.; Schlauch, K.; Rath, A.
10.1101/2020.08.20.258764 — plant biology — Posted on 2020-08-20
1634 A Multi-pronged Screening Approach Targeting Inhibition of ETV6 PNT Domain Polymerization
Gerak, C. A. N.; Zhang, S. M.; Balgi, A. D.; Sadowski, I. J.; Sessions, R. B.; McIntosh, L. P.; Roberge, M.
10.1101/2020.08.20.258525 — biochemistry — Posted on 2020-08-20
1635 Patterning the embryonic pulmonary mesenchyme
Goodwin, K.; Jaslove, J. M.; Tao, H.; Zhu, M.; Hopyan, S.; Nelson, C. M.
10.1101/2020.08.20.259101 — developmental biology — Posted on 2020-08-20
1637 Susceptibility of raccoon dogs for experimental SARS-CoV-2 infection
Freuling, C. M.; Breithaupt, A.; Mueller, T.; Sehl, J.; Balkema-Buschmann, A.; Rissmann, M.; Klein, A.; Wylezich, C.; Hoeper, D.; Wernike, K.; Aebischer, A.; Hoffmann, D.; Friedrichs, V.; Dorhoi, A.; Groschup, M.; Beer, M.; Mettenleiter, T. C.
10.1101/2020.08.19.256800 — microbiology — Posted on 2020-08-20
1639 A rapid and efficient screening system for neutralizing antibodies and its application for the discovery of potent neutralizing antibodies to SARS-CoV-2 S-RBD
Han, X.; Wang, Y.; Li, S.; Tang, N.; Hu, C.; Li, T.; Xie, Y.; Shen, M.; Wang, J.; Gu, C.; Hu, J.; Gong, F.; Wu, R.; Gao, F.; Huang, J.; Mu, S.; Luo, F.; Long, Y.; Song, S.; Long, S.; Hao, Y.; Chen, Q.; Li, L.; Wu, Y.; Xu, W.; Cai, X.; Gao, Q.; Zhang, G.; He, C.; Wang, K.; Deng, K.; Du, L.; Nai, Y.; Wang, W.; Huang, A.; Jin, A.
10.1101/2020.08.19.253369 — immunology — Posted on 2020-08-20
1640 Proteomics characterisation of the L929 cell supernatant and its role in BMDM differentiation
Heap, R. E.; Peltier, J.; Heunis, T.; Marin Rubio, J. L.; Dannoura, A.; Moore, A.; Trost, M.
10.1101/2020.08.20.259515 — immunology — Posted on 2020-08-20
1641 Defining the RBPome of T helper cells to study higher order post-transcriptional gene regulation
Hoefig, K. P.; Reim, A.; Gallus, C.; Wong, E. H.; Behrens, G.; Conrad, C.; Xu, M.; Ito-Kureha, T.; Defourny, K.; Geerlof, A.; Mautner, J.; Hauck, S. M.; Baumjohann, D.; Feederle, R.; Mann, M.; Wierer, M.; Glasmacher, E.; Heissmeyer, V.
10.1101/2020.08.20.259234 — immunology — Posted on 2020-08-20
1642 SARS-CoV-2 Quasispecies provides insight into its genetic dynamics during infection
Sun, F.; Wang, X.; Tan, S.; Dan, Y.; Lu, Y.; Zhang, J.; Xu, J.; Tan, Z.; Xiang, X.; Zhou, Y.; He, W.; Wan, X.; Zhang, W.; Chen, Y.; Tan, W.; Deng, G.
10.1101/2020.08.20.258376 — pathology — Posted on 2020-08-20
1644 Single cell RNA sequencing redefines the mesenchymal cell landscape of mouse endometrium
Kirkwood, P. M.; Gibson, D. A.; Smith, J. R.; Wilson-Kanamori, J. R.; Kelepouri, O.; Esnal-Zufiaurre, A.; Dobie, R.; Henderson, N. C.; Saunders, P. T.
10.1101/2020.08.20.257246 — physiology — Posted on 2020-08-20
1646 Rethinking glottal midline detection
Kist, A. M.; Zilker, J.; Gomez, P.; Schützenberger, A.; Döllinger, M.
10.1101/2020.08.20.257428 — bioengineering — Posted on 2020-08-20
1649 Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord
Danesin, C.; Darche-Gabinaud, R.; Escalas, N.; Bouguetoch, V.; Cochard, P.; Al Oustah, A.; Ohayon, D.; Glise, B.; Soula, C.
10.1101/2020.08.20.258707 — developmental biology — Posted on 2020-08-20
1657 rMVP: A Memory-efficient, Visualization-enhanced, and Parallel-accelerated tool for Genome-Wide Association Study
Yin, L.; Zhang, H.; Tang, Z.; Xu, J.; Yin, D.; Zhang, Z.; Yuan, X.; Zhu, M.; Zhao, S.; Li, X.; Liu, X.
10.1101/2020.08.20.258491 — genetics — Posted on 2020-08-20
1662 Neuronal death in pneumococcal meningitis is triggered by pneumolysin and pilus-1 interactions with β-actin
Tabusi, M.; Thorsdottir, S.; Lysandrou, M.; Narciso, A. R.; Minoia, M.; Henriques-Normark, B.; Iovino, F.
10.1101/2020.08.20.258681 — microbiology — Posted on 2020-08-20
1663 Identification of Chlorophyll a-b Binding Protein AB96 as a novel TGFbeta1 binding agent.
Lynham, S.; Grundland Freile, F.; Puri, N. M.; O'Reilly, N.; Mitchell, G. H.; Wells, T.; Willcox, M.; Beatson, R.
10.1101/2020.08.20.258590 — immunology — Posted on 2020-08-20
1664 Early life stress targets the transcriptional signature and functional properties of voltage gated-sodium (Nav) channels in hippocampal NG2+ glia.
Treccani, G.; Yigit, H.; Lingner, T.; Schleussner, V.; Wennstrom, M.; Herzog, D. P.; Fricke, M.; Wegener, G.; Mittmann, T.; Trotter, J.; Muller, M.
10.1101/2020.08.19.257113 — neuroscience — Posted on 2020-08-20
1669 Niche-derived soluble DLK1 promotes glioma stemness and growth
Grassi, E. S.; Jeannot, P.; Pantazopoulou, V.; Berg, T. J.; Pietras, A.
10.1101/2020.08.20.258608 — cancer biology — Posted on 2020-08-20
1672 Centrosome amplification mediates small extracellular vesicles secretion via lysosome disruption
Godinho, S. A.; Adams, S. D.; Csere, J.; D'angelo, G.; Carter, E. P.; Arnandis, T.; Dodel, M.; Kocher, H.; Grose, R.; Raposo, G.; Mardakheh, F. K.
10.1101/2020.08.19.257162 — cell biology — Posted on 2020-08-20
1673 SARS-CoV-2 infection dynamics in lungs of African green monkeys
Speranza, E.; Williamson, B. N.; Feldmann, F.; Sturdevant, G. L.; Perez-Perez, L.; Mead-White, K.; Smith, B. J.; Lovaglio, J.; Martens, C.; Munster, V.; Okumura, A.; Shaia, C.; Feldmann, H.; Best, S. M.; de Wit, E.
10.1101/2020.08.20.258087 — microbiology — Posted on 2020-08-20
1675 An effective, safe and cost-effective cell-based chimeric vaccine against SARS-CoV2
Cheng, z.; Zhang, D.; Liu, X.; Miao, J.; wang, J.; Guo, H.; Yan, W.; Zhang, Z.; Lu, S.; Zhang, N.; Wang, J.; Zhang, Z.; Liu, W.; Zhang, Y.; Zhang, L.; Dong, J.; Lemoine, N. R.; Wang, Y.
10.1101/2020.08.19.258244 — immunology — Posted on 2020-08-20
1676 A Human-Immune-System mouse model for COVID-19 research(DRAGA mouse: HLA-A2.HLA-DR4.Rag1KO.IL-2Rγc KO.NOD)
Brumeanu, T.-D.; Vir, P.; Shashikumar, S.; Karim, A. F.; Kar, S.; Chung, K. K.; Pratt, K. P.; Casares, S. A.
10.1101/2020.08.19.251249 — immunology — Posted on 2020-08-20
1677 Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells
Parker, R.; Partridge, T.; Wormald, C.; Kawahara, R.; Stalls, V.; Aggelakopoulou, M.; Parker, J.; Powell Doherty, R.; Ariosa-Morejon, Y.; Lee, E.; Saunders, K.; Haynes, B. F.; Acharya, P.; Thaysen-Andersen, M.; Borrow, P.; Ternette, N.
10.1101/2020.08.19.255901 — immunology — Posted on 2020-08-20
1678 Mice learn multi-step routes by memorizing subgoal locations
Shamash, P.; Olesen, S. F.; Iordanidou, P.; Campagner, D.; Nabhojit, B.; Branco, T.
10.1101/2020.08.19.256867 — neuroscience — Posted on 2020-08-20
1679 Repeated parallel losses of inflexed stamens in Moraceae: phylogenomics and generic revision of the tribe Moreae and the reinstatement of the tribe Olmedieae (Moraceae)
Gardner, E. M.; Garner, M.; Cowan, R.; Dodsworth, S.; Epitawalage, N.; Arifiani, D.; Sahromi, S.; Baker, W. J.; Forest, F.; Maurin, O.; Zerega, N. J.; Monro, A. K.; Hipp, A. L.
10.1101/2020.04.08.030452 — plant biology — Posted on 2020-08-20
1681 Maintenance of adaptive dynamics and no detectable load in a bottlenecked range-edge out-crossing plant population
Takou, M.; Hämälä, T.; Koch, E.; Steige, K. A.; Dittberner, H.; Yant, L.; Genete, M.; Sunyaev, S.; Castric, V.; Vekemans, X.; Savolainen, O.; de Meaux, J.
10.1101/709873 — evolutionary biology — Posted on 2020-08-20
1682 Tau, XMAP215/Msps and Eb1 jointly regulate microtubule polymerisation and bundle formation in axons
Hahn, I.; Voelzmann, A.; Parkin, J.; Fuelle, J. B.; Slater, P. G.; Lowery, L. A.; Sanchez-Soriano, N.; Prokop, A.
10.1101/2020.08.19.257808 — cell biology — Posted on 2020-08-20
1685 How mu-Opioid Receptor Recognizes Fentanyl
Vo, Q. N.; Mahinthichaichan, P.; Shen, J.; Ellis, C. R.
10.1101/2020.08.16.253013 — biophysics — Posted on 2020-08-20
1686 Extreme Y chromosome polymorphism corresponds to five male reproductive morphs
Sandkam, B. A.; Almeida, P.; Darolti, I.; Furman, B. L.; van der Bijl, W.; Morris, J.; Bourne, G. R.; Breden, F.; Mank, J. E.
10.1101/2020.08.19.258434 — genomics — Posted on 2020-08-20
1687 Population genomics of two closely related anhydrobiotic midges reveals differences in adaptation to extreme desiccation
Shaykhutdinov, N. M.; Klink, G. V.; Garushyants, S. K.; Kozlova, O. S.; Cherkasov, A. V.; Kikawada, T.; Okuda, T.; Pemba, D.; Deviatiiarov, R. M.; Gazizova, G. R.; Penin, A. A.; Shagimardanova, E. I.; Cornette, R.; Gusev, O. A.; Bazykin, G. A.
10.1101/2020.08.19.255828 — evolutionary biology — Posted on 2020-08-20
1689 Curing genetic skin disease through altered replication stress response
Miyauchi, T.; Suzuki, S.; Takeda, M.; Peh, J. T.; Aiba, M.; Natsuga, K.; Fujita, Y.; Takeichi, T.; Sakamoto, T.; Akiyama, M.; Shimizu, H.; Nomura, T.
10.1101/2020.08.19.255430 — molecular biology — Posted on 2020-08-20
1690 GMO LABELING IN FOOD PRODUCTS IN MONTEVIDEO, URUGUAY
Arleo, M.; Benavente, P.; Cardozo, V.; Katz, A.; Vazquez, S.; Da Silva, A.; Legnani, M.; Martinez Debat, C.
10.1101/2020.08.17.254243 — molecular biology — Posted on 2020-08-20
1692 PACAP induces light aversion in mice by an inheritable mechanism independent of CGRP
Kuburas, A.; Mason, B. N.; Hing, B.; Reis, A. S.; Sowers, L. P.; Moldovan Loomis, C.; Garcia-Martinez, L. F.; Russo, A. F.
10.1101/2020.08.20.255968 — neuroscience — Posted on 2020-08-20
1695 The Molecular Landscape of the Aging Mouse Liver
Williams, E. G.; Pfister, N.; Roy, S.; Statzer, C.; Ingels, J.; Bohl, C.; Hasan, M.; Cuklina, J.; Buhlmann, P.; Zamboni, N.; Lu, L.; Ewald, C. Y.; Williams, R. W.; Aebersold, R.
10.1101/2020.08.20.222968 — systems biology — Posted on 2020-08-20
1698 SuperStructure: a Parameter-Free Super-Structure Identifier for SMLM Data
Marenda, M.; Lazarova, E.; van de Linde, S.; Gilbert, N.; Michieletto, D.
10.1101/2020.08.19.254540 — bioinformatics — Posted on 2020-08-20
1699 Troxerutin acts on complement mediated inflammation to ameliorate arthritic symptoms in rats.
Sahu, D.; Biswal, S. C.; Malik, M. Z.; Sahu, S.; Kaushik, S. R.; Sharma, S.; Saini, E.; Arya, R.; Rastogi, A.; Sharma, S.; Sen, S.; Singh, R. K. B.; Nanda, R.; Panda, A. K.
10.1101/2020.08.18.253427 — biochemistry — Posted on 2020-08-20
1701 Comparing Lifeact and Phalloidin for Super-resolution Imaging of Actin in Fixed Cells
Mazloom-Farsibaf, H.; Farzam, F.; Fazel, M.; Wester, M. J.; Meddens, M. B. M.; Lidke, K. A.
10.1101/2020.08.19.248898 — cell biology — Posted on 2020-08-20
1702 A novel oxidase from Alcaligenes sp. HO-1 oxidizes hydroxylamine to N2
Wu, M.-R.; Miao, L.-L.; Liu, Y.; Hou, T.-T.; Ai, G.-M.; Ma, L.; Zhu, H.-Z.; Zhu, Y.-X.; Gao, X.-Y.; Qin, Y.-L.; Wu, T.; Shen, X.-H.; Jiang, C.-Y.; Herbold, C. W.; Wagner, M.; Li, D.-F.; Liu, Z.-P.; Liu, S.-J.
10.1101/2020.08.20.256677 — microbiology — Posted on 2020-08-20
1704 Spontaneous Axonal ER Ca2+ Waves Mediate a Shift From Action Potential-Dependent to Independent Glutamate Release in the YAC128 HD-Model
Mackay, J. P.; Smith-Dijak, A. I.; Koch, E. T.; Zhang, P.; Fung, E.; Nassrallah, W. B.; Buren, C.; Schmidt, M.; Hayden, M. R.; Raymond, L. A.
10.1101/2020.01.31.929299 — neuroscience — Posted on 2020-08-20
1705 Brain Amyloid and the Transition to Dementia in Down Syndrome
Keator, D. B.; Doran, E.; Taylor, L. A.; Phelan, M. J.; Hom, C.; Tseung, K.; van Erp, T. G. M.; Potkin, S. G.; Brickman, A. M.; Rosas, D. H.; Yassa, M. A.; Silverman, W.; Lott, I. T.
10.1101/2020.08.19.257790 — neuroscience — Posted on 2020-08-20
1710 Cytoplasmic polyadenylation by TENT5A is required for proper bone formation
Dziembowski, A.; Gewartowska, O.; Krawczyk, P.; Mroczek, S.; Kusio-Kobiałka, M.; Tarkowski, B.; Aranaz Novaliches, G.; Spoutil, F.; Benada, O.; Kofronova, O.; Szwedziak, P.; Cysewski, D.; Gruchota, J.; Szpila, M.; Chlebowski, A.; Sedlacek, R.; Prochazka, J.
10.1101/2020.08.18.256115 — genetics — Posted on 2020-08-20
1712 DNA oxidation induced by fetal exposure to BPA agonists impairs female meiosis
Abdallah, S.; Moison, D.; Wieckowski, M.; Messiaen, S.; Martini, E.; Campalans, A.; Radicella, J. P.; Livera, G.; Rouiller-Fabre, V.; Guerquin, M.-J.
10.1101/2020.08.17.253724 — molecular biology — Posted on 2020-08-20
1713 Vascular control of the CO2/H+ dependent drive to breathe
Cleary, C. M.; Moreira, T. S.; Takakura, A. C.; Nelson, M. T.; Longden, T.; Mulkey, D. K.
10.1101/2020.08.19.257386 — neuroscience — Posted on 2020-08-20
1715 A robust and versatile nanobody platform for drug delivery
Shen, Z.; Xiang, Y.; Vergara, S.; Chen, A.; Xiao, Z.; Santiago, U.; Jin, C.; Sang, Z.; Luo, J.; Chen, K.; Schneidman-Duhovny, D.; Camacho, C. J.; Calero, G.; Hu, B.; Shi, Y.
10.1101/2020.08.19.257725 — bioengineering — Posted on 2020-08-20
1717 Tissue-specific transcription footprinting using RNA PoI DamID (RAPID) in C. elegans
Gomez-Saldivar, G.; Osuna-Luque, J.; Glauser, D. A.; Jarriault, S.; Meister, P.
10.1101/2020.08.19.257873 — genetics — Posted on 2020-08-20
1719 Activity of the GHRH Antagonist MIA602 and its Underlying Mechanisms of Action in sarcoidosis
Zhang, C.; Tian, R.; Dreifus, E. M.; Holt, G.; Cai, R.; Griswold, A. J.; Bejarano, P.; Jackson, R.; Schally, A. V.; Mirsaeidi, M.
10.1101/2020.08.19.257915 — immunology — Posted on 2020-08-20
1722 A Simulation Study Investigating Potential Diffusion-based MRI Signatures of Microstrokes
Damseh, R.; Lu, Y.; Lu, X.; Zhang, C.; J. Marchand, P.; Corbin, D.; Pouliot, P.; Cheriet, F.; Lesage, F.
10.1101/2020.08.19.257741 — neuroscience — Posted on 2020-08-20
1725 Neural and subjective effects of inhaled DMT in natural settings
Pallavicini, C.; Cavanna, F.; Zamberlan, F.; de la Fuente, L. A.; Arias, M.; Romero, M. C.; Carhart-Harris, R.; Timmermann, C.; Tagliazucchi, E.
10.1101/2020.08.19.258145 — neuroscience — Posted on 2020-08-20
1728 Design of synthetic human gut microbiome assembly and function
Clark, R. L.; Connors, B.; Stevenson, D. M.; Hromada, S. E.; Hamilton, J. J.; Amador-Noguez, D.; Venturelli, O. S.
10.1101/2020.08.19.241315 — systems biology — Posted on 2020-08-20
1729 Collaboration of multiple pathways in making a compound leaf
Israeli, A.; Ben Herzel, O.; Borko, Y.; Shwartz, I.; Ben Gera, H.; Harpaz-Saad, S.; Bar, M.; Efroni, I.; Ori, N.
10.1101/2020.08.19.257550 — plant biology — Posted on 2020-08-20
1731 Molecular interaction mechanism of a 14-3-3 protein with a phosphorylated peptide elucidated by enhanced conformational sampling
Higo, J.; Kawabata, T.; Kusaka, A.; Kasahara, K.; Kamiya, N.; Fukuda, I.; Mori, K.; Hata, Y.; Fukunishi, Y.; Nakamura, H.
10.1101/2020.05.24.113209 — biophysics — Posted on 2020-08-20
1734 Accurate identification and quantification of commensal microbiota bound by host immunoglobulins
Jackson, M. A.; Pearson, C.; Ilott, N. E.; Huus, K. E.; Hegazy, A. N.; Webber, J.; Finlay, B. B.; Macpherson, A. J.; Powrie, F.; Lam, L. H.
10.1101/2020.08.19.257501 — bioinformatics — Posted on 2020-08-20
1737 Integrated environmental and genomic analysis reveals the drivers of local adaptation in African indigenous chickens
Gheyas, A. A.; Trujillo, A. V.; Kebede, A.; Lozano-Jaramillo, M.; Dessie, T.; Smith, J.; Hanotte, O.
10.1101/2020.08.19.257212 — genomics — Posted on 2020-08-20
1740 The genetic architecture and genomic context of glyphosate resistance
Kreiner, J. M.; Tranel, P. M.; Weigel, D.; Stinchcombe, J. R.; Wright, S.
10.1101/2020.08.19.257972 — evolutionary biology — Posted on 2020-08-20
1741 Myanmar's terrestrial ecosystems: status, threats and conservation opportunities
Murray, N. J.; Keith, D. A.; Duncan, A.; Tizard, R.; Ferrer-Paris, J. R.; Worthington, T. A.; Armstrong, K.; Hlaing, N.; Htut, W. T.; Oo, A. H.; Ya, K. Z.; Grantham, H.
10.1101/2020.08.18.256750 — ecology — Posted on 2020-08-20
1742 Holocene plant diversity dynamics shows a distinct biogeographical pattern in temperate Europe
Rolecek, J.; Abraham, V.; Vild, O.; Svitavska Svobodova, H.; Jamrichova, E.; Pleskova, Z.; Pokorny, P.; Kunes, P.
10.1101/2020.08.19.257584 — ecology — Posted on 2020-08-20
1748 Impaired miRNA degradation by post-transcriptional addition of 3' cytosine and adenine in T cell activation
Rodriguez-Galan, A.; Dosil, S. G.; Gomez, M. J.; Fernandez-Delgado, I.; Sanchez-Cabo, F.; Sanchez-Madrid, F.
10.1101/2020.08.19.257816 — immunology — Posted on 2020-08-20
1749 An Industrial-Grade Brain Imaging-Based Deep Learning Classifier
Lu, B.; Li, H.-X.; Chang, Z.-K.; Li, L.; Chen, N.-X.; Zhu, Z.-C.; Zhou, H.-X.; Fan, Z.; Yang, H.; Chen, X.; Yan, C.-G.
10.1101/2020.08.18.256594 — neuroscience — Posted on 2020-08-20
1755 Genetic variation for tolerance to the downy mildew pathogen Peronospora variabilis in genetic resources of quinoa (Chenopodium quinoa)
Colque-Little, C. X.; Correa Abondano, M.; Sogard Lund, O.; Buchvaldt Amby, D.; Piepho, H.-P.; Andreasen, C.; Schmöckel, S. M.; Schmid, K. J.
10.1101/2020.08.19.257535 — plant biology — Posted on 2020-08-20
1763 Tau, XMAP215/Msps and Eb1 jointly regulate microtubule polymerisation and bundle formation in axons
Hahn, I.; Voelzmann, A.; Parkin, J.; Fuelle, J. B.; Slater, P. G.; Lowery, L. A.; Sanchez-Soriano, N.; Prokop, A.
10.1101/2020.08.19.257808 — cell biology — Posted on 2020-08-20
1769 Identification of Wee1 as Target in Combination with Avapritinib for the Treatment of Gastrointestinal Stromal Tumors
Ye, S.; Sharipova, D.; Kozinova, M.; Klug, L.; D'Souza, J.; Belinsky, M. G.; Johnson, K. J.; Einarson, M. B.; Devarajan, K.; Zhou, Y.; Litwin, S.; Heinrich, M. C.; DeMatteo, R.; von Mehren, M.; Duncan, J.; Rink, L.
10.1101/2020.06.07.138693 — cancer biology — Posted on 2020-08-19
1771 Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus
Wang, S.; Reeve, S. M.; Ojewole, A. A.; Frenkel, M. S.; Holt, G. T.; Gainza, P.; Keshipeddy, S.; Fowler, V. G.; Wright, D. L.; Donald, B. R.
10.1101/2020.07.28.224667 — biochemistry — Posted on 2020-08-19
1774 Modular HUWE1 architecture serves as hub for degradation of cell-fate decision factors
Hunkeler, M.; Jin, C. Y.; Ma, M. W.; Overwijn, D.; Monda, J. K.; Bennett, E. J.; Fischer, E. S.
10.1101/2020.08.19.257352 — molecular biology — Posted on 2020-08-19
1778 Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation
Nalle, S.; Barreira da Silva, R.; Zhang, H.; Decker, M.; Chalouni, C.; Xu, M.; Posthuma, G.; de Maziere, A.; Klumperman, J.; Baz Morelli, A.; Fleire, S.; Verkman, A.; Trombetta, S.; Albert, M.; Mellman, I.
10.1101/2020.08.19.256966 — immunology — Posted on 2020-08-19
1782 High Gamma Cortical Processing of Continuous Speech in Younger and Older Listeners
Kulasingham, J. P.; Brodbeck, C.; Presacco, A.; Kuchinsky, S. E.; Anderson, S.; Simon, J. Z.
10.1101/2019.12.19.883314 — neuroscience — Posted on 2020-08-19
1784 Cnr2 is important for Ribbon Synapse Maturation and Function in Hair Cells and Photoreceptors
Colon-Cruz, L.; Rodriguez-Morales, R.; Santana-Cruz, A.; Cantres-Velez, J.; Torrado-Tapias, A.; Yudowski, G.; Kensler, R.; Marie, B.; Burgess, S. M.; Renaud, O.; Varshney, G. K.; Behra, M.
10.1101/2020.08.18.253120 — neuroscience — Posted on 2020-08-19
1785 Online narrative guides for illuminating tissue atlas data and digital pathology images
Rashid, R.; Chen, Y.-A.; Hoffer, J.; Muhlich, J. L.; Lin, J.-R.; Krueger, R.; Pfister, H.; Mitchell, R.; Santagata, S.; Sorger, P.
10.1101/2020.03.27.001834 — scientific communication and education — Posted on 2020-08-19
1786 A Deep Learning Approach for Rapid Mutational Screening in Melanoma
Kim, R.; Nomikou, S.; Coudray, N.; Jour, G.; Dawood, Z.; Hong, R.; Esteva, E.; Sakellaropoulos, T.; Donnelly, D.; Moran, U.; Hatzimemos, A.; Weber, J. S.; Razavian, N.; Aifantis, I.; Fenyo, D.; Snuderl, M.; Shapiro, R.; Berman, R. S.; Osman, I.; Tsirigos, A.
10.1101/610311 — pathology — Posted on 2020-08-19
1788 Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis
Ferrarini, M. G.; Lal, A.; Rebollo, R.; Gruber, A.; Guarracino, A.; Martinez Gonzalez, I.; Floyd, T.; Siqueira de Oliveira, D.; Shanklin, J.; Beausoleil, E.; Pusa, T.; Pickett, B.; Aguiar-Pulido, V.
10.1101/2020.07.28.225581 — bioinformatics — Posted on 2020-08-19
1789 A computationally designed fluorescent biosensor for D-serine
Vongsouthi, V.; Whitfield, J. H.; Unichenko, P.; Mitchell, J. A.; Breithausen, B.; Khersonsky, O.; Kremers, L.; Janovjak, H.; Monai, H.; Hirase, H.; Fleishman, S. J.; Henneberger, C.; Jackson, C. J.
10.1101/2020.08.18.255380 — biochemistry — Posted on 2020-08-19
1790 No evidence for increased transmissibility from recurrent mutations in SARS-CoV-2
van Dorp, L.; Richard, D.; Tan, C. C.; Shaw, L. P.; Acman, M.; Balloux, F.
10.1101/2020.05.21.108506 — genomics — Posted on 2020-08-19
1791 Gigantic Genomes Can Provide Empirical Tests of TE Dynamics Models -- An Example from Amphibians
Wang, J.; Itgen, M. W.; Wang, H.; Gong, Y.; Jiang, J.; Li, J.; Sun, C.; Sessions, S. K.; Mueller, R. L.
10.1101/2020.08.19.257527 — genomics — Posted on 2020-08-19
1796 Oligomeric hypercomplex of the complete oxidative phosphorylation system in heart mitochondria.
Nesterov, S. V.; Chesnokov, Y. M.; Kamyshinsky, R. A.; Panteleeva, A. A.; Lyamzaev, K. G.; Vasilov, R. G.; Yaguzhinsky, L. S.
10.1101/2020.08.17.253922 — molecular biology — Posted on 2020-08-19
1799 A small molecule screen identified N-Acetyl-L-cysteine for promoting ex vivo growth of single circulating tumor cells
Teng, T.; Kamal, M.; Iriondo, O.; Amzaleg, Y.; Luo, C.; Thomas, A.; Lee, G.; Nguyen, J. D.; Smith, A.; Sposto, R.; Yu, M.
10.1101/2020.08.19.257378 — cancer biology — Posted on 2020-08-19
1800 Energy landscape steering in SecYEG mediates dynamic coupling in ATP driven protein translocation
Crossley, J.; Fessl, T.; Watson, M. A.; Watkins, D.; Corey, R. A.; Allen, W. J.; Sabir, T.; Radford, S. E.; Collinson, I.; Tuma, R.
10.1101/793943 — biophysics — Posted on 2020-08-19
1801 Substrate Recognition by γ-Glutamyltransferase: A Molecular Dynamics Simulations Study
Oliva, F.; Flores-Canales, J. C.; Pieraccini, S.; Morelli, C. F.; Sironi, M.; Schiott, B.
10.1101/2020.04.20.050500 — biophysics — Posted on 2020-08-19
1803 SARS-CoV-2 spike protein predicted to form complexes with host receptor protein orthologues from a broad range of mammals
Lam, S. D.; Bordin, N.; Waman, V. P.; Scholes, H. M.; Ashford, P.; Sen, N.; van Dorp, L.; Rauer, C.; Dawson, N. L.; Pang, C. S.; Abbasian, M.; Sillitoe, I.; Edwards, S. J.; Fraternali, F.; Lees, J. G.; Santini, J. M.; Orengo, C. A.
10.1101/2020.05.01.072371 — bioinformatics — Posted on 2020-08-19
1804 CRISPR-Decryptr reveals cis-regulatory elements from noncoding perturbation screens
Rasmussen, A. W.; Äijö, T.; Gabitto, M. I.; Carriero, N.; Sanjana, N.; Skok, J.; Bonneau, R.
10.1101/2020.08.13.247007 — bioinformatics — Posted on 2020-08-19
1807 Cell-Cell Adhesion During Nephron Development Is Driven by Wnt/PCP Formin Daam1
Miller, R. K.; Krneta-Stankic, V.; Corkins, M. E.; Kloc, M.; Gladden, A. B.; Paulucci-Holthauzen, A.
10.1101/2020.08.18.256123 — developmental biology — Posted on 2020-08-19
1808 The nanoscale anatomy of exocytic dense-core vesicles in neuroendocrine cells
Prasai, B.; Haber, G. J.; Strub, M.-P.; Ciemniecki, J. A.; Sochacki, K. A.; Taraska, J. W.
10.1101/2020.08.19.257733 — cell biology — Posted on 2020-08-19
1810 NVX-CoV2373 vaccine protects cynomolgus macaque upper and lower airways against SARS-CoV-2 challenge
Guebre-Xabier, M.; Patel, N.; Tian, J.-H.; Zhou, B.; Maciejewski, S.; Lam, K.; Portnoff, A. D.; Massare, M. J.; Frieman, M. B.; Piedra, P. A.; Ellingsworth, L. R.; Glenn, G.; Smith, G.
10.1101/2020.08.18.256578 — immunology — Posted on 2020-08-19
1811 Molecular tracking devices quantify antigen distribution and archiving in the lymph node
Walsh, S. L.; Sheridan, R. M.; Doan, T.; Lucas, E. D.; Ware, B.; Fu, R.; Burchill, M.; Hesselberth, J. R.; Tamburini, B. J.
10.1101/2020.08.19.219527 — immunology — Posted on 2020-08-19
1813 Methionine stress induces ferroptosis in methionine dependent cancer cells
Wallis, K. F.; Bird, J. T.; Gies, A. J.; Mackintosh, S. G.; Tackett, A. J.; Byrum, S.; Miousse, I. R.
10.1101/2020.08.18.254490 — cancer biology — Posted on 2020-08-19
1814 SARS-CoV-2 ORF9c Is a Membrane-Associated Protein that Suppresses Antiviral Responses in Cells
Dominguez Andres, A.; Feng, Y.; Campos, A. R.; Yin, J.; Yang, C.-C.; James, B.; Murad, R.; Kim, H.; Deshpande, A. J.; Gordon, D. E.; Krogan, N. J.; Pippa, R.; Ronai, Z. A.
10.1101/2020.08.18.256776 — bioinformatics — Posted on 2020-08-19
1815 Neutralizing antibody-dependent and -independent immune responses against SARS-CoV-2 in cynomolgus macaques
Ishigaki, H.; Nakayama, M.; Kitagawa, Y.; Nguyen, C. T.; Hayashi, K.; Shiohara, M.; Gotoh, B.; Itoh, Y.
10.1101/2020.08.18.256446 — microbiology — Posted on 2020-08-19
1816 Human organ chip-enabled pipeline to rapidly repurpose therapeutics during viral pandemics
Si, L.; Bai, H.; Rodas, M.; Cao, W.; Oh, C. Y.; Jiang, A.; Moller, R.; Hoagland, D.; Oishi, K.; Horiuchi, S.; Uhl, S.; Blanco-Melo, D.; Albrecht, R. A.; Liu, W.-C.; Jordan, T.; Nilsson-Payant, B. E.; Logue, J.; Haupt, R.; McGrath, M.; Weston, S.; Nurani, A.; Kim, S. M.; Zhu, D. Y.; Benam, K. H.; Goyal, G.; Gilpin, S.; Prantil-Baun, R.; Powers, R. K.; Carlson, K.; Frieman, M.; tenOever, B. R.; Ingber, D. E.
10.1101/2020.04.13.039917 — microbiology — Posted on 2020-08-19
1819 Brain activity fluctuations propagate as waves traversing the cortical hierarchy
Gu, Y.; Sainburg, L. E.; Kuang, S.; Han, F.; Williams, J. W.; Liu, Y.; Zhang, N.; Zhang, X.; Leopold, D. A.; Liu, X.
10.1101/2020.08.18.256610 — neuroscience — Posted on 2020-08-19
1820 Understanding metabolic behaviour in whole-cell model output
Landon, S.; Chalkley, O.; Breese, G.; Grierson, C.; Marucci, L.
10.1101/2020.08.19.257147 — systems biology — Posted on 2020-08-19
1822 Low replication stress leads to specific replication timing advances associated to chromatin remodelling in cancer cells
Courtot, L.; Maric, C.; Bournique, E.; Guitton-Sert, L.; Madrid-Mencia, M.; Pancaldi, V.; Hoffmann, J.-S.; Cadoret, J.-C.; Bergoglio, V.
10.1101/2020.08.19.256883 — cancer biology — Posted on 2020-08-19
1824 Endothelial Barrier Function is co-regulated at Vessel Bifurcations by Fluid Forces and Sphingosine-1-Phosphate
Akbari, E. W.; Spychalski, G. B.; Menyhert, M. M.; Rangharajan, K. K.; Prakash, S.; Song, J. W.
10.1101/2020.08.18.256586 — bioengineering — Posted on 2020-08-19
1826 A computationally designed fluorescent biosensor for D-serine
Vongsouthi, V.; Whitfield, J. H.; Unichenko, P.; Mitchell, J. A.; Breithausen, B.; Khersonsky, O.; Kremers, L.; Monai, H.; Hirase, H.; Fleishman, S. J.; Henneberger, C.; Jackson, C. J.
10.1101/2020.08.18.255380 — biochemistry — Posted on 2020-08-19
1827 Genetics of mouse behavioral and peripheral neural responses to sucrose
Lin, C.; Inoue, M.; Li, X.; Bosak, N.; Ishiwatari, Y.; Tordoff, M.; Beauchamp, G. K.; Bachmanov, A.; Reed, D. R.
10.1101/2020.08.19.253989 — animal behavior and cognition — Posted on 2020-08-19
1828 Chronic oxytocin-driven alternative splicing of CRFR2α induces anxiety
Winter, J.; Meyer, M.; Berger, I.; Peters, S.; Royer, M.; Bianchi, M.; Stang, S.; Langgartner, D.; Reber, S. O.; Kuffner, K.; Schmidtner, A. K.; Hartmann, F.; Bludau, A.; Bosch, O. J.; Slattery, D. A.; van den Burg, E. H.; Neumann, I. D.; Jurek, B.
10.1101/2020.08.19.255844 — animal behavior and cognition — Posted on 2020-08-19
1829 Reprogramming enriches for somatic cell clones with small scale mutations in cancer-associated genes
Kosanke, M.; Osetek, K.; Haase, A.; Wiehlmann, L.; Davenport, C.; Schwarzer, A.; Adams, F.; Schambach, A.; Merkert, S.; Wunderlich, S.; Menke, S.; Dorda, M.; Martin, U.
10.1101/2020.08.19.257238 — genomics — Posted on 2020-08-19
1830 A toolkit to generate inducible and interconvertible Drosophila transgenes
Wendler, F.; Park, S.; Hill, C.; Galasso, A.; Chang, K. R.; Awan, I.; Sudarikova, Y.; Bustamante, M.; Liu, S.; Sung, E.; Aisabonoko, G.; Kim, S. K.; Lopez, L. A. B.
10.1101/2020.08.18.256461 — genetics — Posted on 2020-08-19
1836 Intracellular nanovesicles mediate integrin trafficking during cell migration
Larocque, G.; La-Borde, P. J.; Wilson, B. J.; Clarke, N. I.; Moore, D. J.; Caswell, P. T.; Royle, S. J.
10.1101/2020.08.19.257287 — cell biology — Posted on 2020-08-19
1839 Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion
Papa, G.; Mallery, D.; Albecka, A.; Welch, L.; Cattin-Ortola, J.; Luptak, J.; Paul, D.; McMahon, H. T.; Goodfellow, I. G.; Carter, A. P.; Munro, S.; James, L. C.
10.1101/2020.08.13.243303 — microbiology — Posted on 2020-08-19
1840 Global population genomic analysis of Mycoplasma bovis isolates reveals transcontinental variations and potential virulence genes
Kumar, R.; Register, K.; Hennings, J.; Moroni, P.; Gioa, G.; Garcia-Fernandez, N.; Nelson, J.; Jelinski, M.; Lysnyansky, I.; Bayles, D.; Alt, D.; Scaria, J.
10.1101/2020.08.19.257345 — microbiology — Posted on 2020-08-19
1841 Lactobacillus rhamnosus attenuates bone loss and maintains bone health by skewing Treg-Th17 cell balance in Ovx mice
Sapra, L.; Dar, H. Y.; Pandey, A.; Kumari, S.; Azam, Z.; Bhardwaj, A.; Shukla, P.; Mishar, P. K.; Verma, B.; Srivastava, R. K.
10.1101/2020.08.19.257048 — immunology — Posted on 2020-08-19
1843 Sodium leak channel as a therapeutic target for neuronal sensitization in neuropathic pain
Zhang, D.; Zhao, W.; Liu, J.; Ou, M.; Liang, P.; Li, J.; Chen, Y.; Liao, D.; Bai, S.; Shen, J.; Chen, X.; Huang, H.; Zhou, C.
10.1101/2020.08.17.253534 — neuroscience — Posted on 2020-08-19
1846 Cnr2 is important for Ribbon Synapse Maturation and Function in Hair Cells and Photoreceptors
Colon-Cruz, L.; Rodriguez-Morales, R.; Santana-Cruz, A.; Castres-Velez, J.; Torrado-Tapias, A.; Yudowski, G.; Kensler, R.; Marie, B.; Burgess, S. M.; Renaud, O.; Varshney, G. K.; Behra, M.
10.1101/2020.08.18.253120 — neuroscience — Posted on 2020-08-19
1847 Distributed source modeling of intracranial stereoelectroencephalographic measurements
Lin, F.-H.; Lee, H.-J.; Ahveninen, J.; Jaaskelainen, I. P.; Yu, H.-Y.; Lee, C.-C.; Chou, C.-C.; Kuo, W.-J.
10.1101/2020.08.18.256669 — neuroscience — Posted on 2020-08-19
1849 Reactive or transgenic increase in microglial TYROBP reveals a TREM2-independent TYROBP-APOE link in wild-type and Alzheimer's-related mice
Audrain, M.; Haure-Mirande, J.-V.; Mleczko, J.; Wang, M.; Griffin, J. K.; Fraser, P.; Zhang, B.; Gandy, S.; Ehrlich, M. E.
10.1101/2020.08.18.254649 — neuroscience — Posted on 2020-08-19
1852 Color compensation in anomalous trichromats assessed with fMRI
Tregillus, K. E.; Isherwood, Z. J.; Vanston, J. E.; Engel, S. A.; MacLeod, D. I. A.; Kuriki, I.; Webster, M. A.
10.1101/2020.08.18.256701 — neuroscience — Posted on 2020-08-19
1854 Single-cell transcriptomics reveals immune response of intestinal cell types to viral infection
Triana, S.; Stanifer, M. L.; Shahraz, M.; Mukenhirn, M.; Kee, C.; Ordonez Rueda, D.; Paulsen, M.; Benes, V.; Boulant, S.; Alexandrov, T.
10.1101/2020.08.19.255893 — systems biology — Posted on 2020-08-19
1857 Boosting photosynthetic machinery and defense priming with chitosan application on tomato plants infected with Fusarium oxysporum f. sp. lycopersici
Carmona, S. L.; Villarreal-Navarrete, A. d. P.; Burbano-David, D.; Gomez-Marroquin, M.; Torres-Rojas, E.; Soto-Suarez, M.
10.1101/2020.08.18.256628 — plant biology — Posted on 2020-08-19
1859 Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model
Qin, S. S.; Han, B. J.; Williams, A.; Jackson, K. M.; Jewell, R.; Chacon, A. C.; Lord, E. M.; Linehan, D. C.; Kim, M.; Reuben, A.; Gerber, S. A. A.; Prieto, P. A.
10.1101/2020.08.18.216259 — cancer biology — Posted on 2020-08-19
1860 Single-cell atlas of tumor clonal evolution in liver cancer
Ma, L.; Wang, L.; Chang, C.-W.; Heinrich, S.; Dominguez, D.; Forgues, M.; Candia, J.; Hernandez, M. O.; Kelly, M.; Zhao, Y.; Tran, B.; Hernandez, J. M.; Davis, J. L.; Kleiner, D. E.; Wood, B. J.; Greten, T. F.; Wang, X. W.
10.1101/2020.08.18.254748 — cancer biology — Posted on 2020-08-19
1861 Role of selective Bioactive Compounds as an Angiotensin Converting Enzyme Inhibitor
Khan, H.; Hussain, T.; Kataria, M.; SETH, A.; Malik, M. Z.; Dash, A.; Chand, S.; KHAN, M. A.
10.1101/2020.08.17.254359 — bioinformatics — Posted on 2020-08-19
1862 Optogenetic activation of heterotrimeric Gi proteins by LOV2GIVe - a rationally engineered modular protein
Garcia-Marcos, M.; Parag-Sharma, K.; Marivin, A.; Maziarz, M.; Luebbers, A.; Nguyen, L. T.
10.1101/2020.08.17.253781 — biochemistry — Posted on 2020-08-19
1864 Concerted evolution reveals co-adapted amino acid substitutions in frogs that prey on toxic toads
Mohammadi, S.; Yang, L.; Harpak, A.; Herrera-Alvarez, S.; Rodriguez-Ordonez, M. d. P.; Peng, J.; Zhang, K.; Storz, J. F.; Dobler, S.; Crawford, A. J.; Andolfatto, P.
10.1101/2020.08.04.234435 — evolutionary biology — Posted on 2020-08-19
1866 Genetically Determined Strength of Natural Killer Cells is Enhanced by Adaptive HLA class I Admixture in East Asians
Deng, Z.; Zhen, J.; Harrison, G. F.; Zhang, G.; Chen, R.; Sun, G.; Yu, Q.; Nemat-Gorgani, N.; Guethlein, L. A.; He, L.; Tang, M.; Gao, X.; Cai, S.; Shortt, J. A.; Gignoux, C. R.; Carrington, M.; Zou, H.; Parham, P.; Hong, W.; Norman, P. J.
10.1101/2020.07.29.227579 — immunology — Posted on 2020-08-19
1868 Multi-centre, multi-vendor reproducibility of 7T QSM and R2* in the human brain: results from the UK7T study
Rua, C.; Clarke, W. T.; Driver, I. D.; Mougin, O.; Morgan, A. T.; Clare, S.; Francis, S.; Muir, K.; Wise, R.; Carpenter, A.; Wiliams, G. B.; Rowe, J. B.; Bowtell, R.; Rodgers, C. T.
10.1101/2020.04.22.055624 — neuroscience — Posted on 2020-08-19
1875 Agonist and antagonist diverted twisting motions of single TRPV1 channel
Fujimura, S.; Mio, K.; Kuramochi, M.; Sekiguchi, H.; Keigo, I.; Mio, M.; Hengphasatporn, K.; Shigeta, Y.; Kubo, T.; Sasaki, Y. C.
10.1101/2020.08.18.255109 — biophysics — Posted on 2020-08-19
1877 Multi-channel intraneural vagus nerve recordings with a novel high-density carbon fiber microelectrode array
Jiman, A. A.; Ratze, D. C.; Welle, E. J.; Patel, P. R.; Richie, J. M.; Bottorff, E. C.; Seymour, J. P.; Chestek, C. A.; Bruns, T. M.
10.1101/2020.05.15.098301 — bioengineering — Posted on 2020-08-19
1878 Validated removal of nuclear pseudogenes and sequencing artefacts from mitochondrial metabarcode data
Andujar, C.; Creedy, T. J.; Arribas, P.; Lopez, H.; Salces-Castellano, A.; Perez-Delgado, A.; Vogler, A. P.; Emerson, B. C.
10.1101/2020.06.17.157347 — evolutionary biology — Posted on 2020-08-19
1881 3D Visualization of Macromolecule Synthesis
Duerr, T. J.; Comellas, E.; Jeon, E. K.; Farkas, J. E.; Joetzjer, M.; Garnier, J.; Shefelbine, S. J.; Monaghan, J. R.
10.1101/2020.06.24.169300 — developmental biology — Posted on 2020-08-19
1882 The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1
Dietz, S.; Almeida, M. V.; Nischwitz, E.; Schreier, J.; Viceconte, N.; Fradera Sola, A.; Renz, C.; Ceron-Noriega, A.; Ulrich, H. D.; Kappei, D.; Ketting, R. F.; Butter, F.
10.1101/2020.08.19.256388 — cell biology — Posted on 2020-08-19
1883 Loss of Fas-signaling in pro-fibrotic fibroblasts impairs homeostatic fibrosis resolution and promotes persistent pulmonary fibrosis
Redente, E. F.; Chakraborty, S.; Sajuthi, S. P.; Black, B. P.; Edelman, B. L.; Seibold, M. A. P.; Riches, D. W. H.
10.1101/2020.08.18.255869 — cell biology — Posted on 2020-08-19
1885 Improved segmentation of the intracranial and ventricular volumes in populations with cerebrovascular lesions and atrophy using 3D CNNs
Ntiri, E. E.; Holmes, M. F.; Mojiri, P.; Ramirez, J.; Gao, F.; Ozzoude, M.; Adamo, S.; Scott, C.; Dowlatshahi, D.; Lawrence-Dewar, J. M.; Kwan, D.; Lang, A. E.; Symons, S.; Bartha, R.; Strother, S.; Tardif, J.-C.; Masellis, M.; Swartz, R. H.; Moody, A.; Black, S.; Goubran, M.
10.1101/2020.03.23.000844 — neuroscience — Posted on 2020-08-19
1886 Multisensory processes can compensate for attention deficits in schizophrenia
Moran, J. K.; Keil, J.; Masurovsky, A.; Gutwinski, S.; Montag, C.; Senkowski, D.
10.1101/2020.08.14.251405 — neuroscience — Posted on 2020-08-19
1889 A Minimally Destructive Protocol for DNA Extraction from Ancient Teeth
Harney, E.; Cheronet, O.; Fernandes, D. M.; Sirak, K.; Mah, M.; Bernardos, R.; Adamski, N.; Broomandkhoshbacht, N.; Callan, K.; Lawson, A. M.; Oppenheimer, J.; Stewardson, K.; Zalzala, F.; Anders, A.; Candilio, F.; Constantinescu, M.; Coppa, A.; Ciobanu, I.; Dani, J.; Gallina, Z.; Genchi, F.; Nagy, E. G.; Hajdu, T.; Hellebrandt, M.; Horvath, A.; Kiraly, A.; Kiss, K.; Kolozsi, B.; Kovacs, P.; Köhler, K.; Lucci, M.; Pap, I.; Popovici, S.; Raczky, P.; Simalcsik, A.; Szeniczey, T.; Vasilyev, S.; Virag, C.; Rohland, N.; Reich, D. E.; Pinhasi, R.
10.1101/2020.08.19.256412 — evolutionary biology — Posted on 2020-08-19
1891 Transcriptional Profiling of Identified Neurons in Leech
Heath-Heckman, E.; Yoo, S.; Winchell, C.; Pellegrino, M.; Angstadt, J.; Lammardo, V.; Bautista, D. M.; de Miguel, F. F.; Weisblat, D. A.
10.1101/2020.08.17.254631 — neuroscience — Posted on 2020-08-19
1894 Munc13 binds and recruits SNAP25 to chaperone SNARE complex assembly
Kalayanasundaram, R. V.; Jin, H.; Li, F.; Shu, T.; Coleman, J.; Yang, J.; Pincet, F.; Zhang, Y.; Krishnakumar, S. S.; Rothman, J. E.
10.1101/2020.08.19.257261 — neuroscience — Posted on 2020-08-19
1895 A Bbs5 mouse model reveals pituitary cilia contributions to developmental abnormalities.
Bentley, M. R.; Engle, S. E.; Haycraft, C. J.; Andersen, R. S.; Croyle, M. J.; Clearman, K. R.; Rains, A. B.; Berbari, N. F.; Yoder, B. K.
10.1101/2020.08.18.256537 — developmental biology — Posted on 2020-08-19
1898 The peptide sensor motif stabilizes the outward-facing conformation of TmrAB
Millan, C. R.; Francis, M.; Thompson, V. F.; Thaker, T. M.; Tomasiak, T. M.
10.1101/2020.01.12.903617 — biochemistry — Posted on 2020-08-19
1900 Deciphering and modelling the TGF-β signalling interplays specifying the dorsal-ventral axis of the sea urchin embryo.
Floc'hlay, S.; Molina Jimenez, M. D.; Hernandez, C.; Haillot, E.; Thomas-Chollier, M.; Lepage, T.; Thieffry, D.
10.1101/2020.02.26.966556 — developmental biology — Posted on 2020-08-19
1902 A distinct growth physiology enhances bacterial growth under rapid nutrient fluctuations
Nguyen, J.; Fernandez, V.; Pontrelli, S.; Sauer, U.; Ackermann, M.; Stocker, R.
10.1101/2020.08.18.256529 — microbiology — Posted on 2020-08-19
1903 Automated and unbiased classification of motor neuron phenotypes with single cell resolution in ALS tissue.
Hagemann, C.; Tyzack, G. E.; Taha, D. M.; Devine, H.; Greensmith, L.; Newcombe, J.; Patani, R.; Serio, A.; Luisier, R.
10.1101/2020.08.17.253773 — neuroscience — Posted on 2020-08-18
1904 Bayesian model selection favors parametric over categorical fMRI subsequent memory models in young and older adults
Soch, J.; Richter, A.; Schuetze, H.; Kizilirmak, J. M.; Assmann, A.; Knopf, L.; Raschick, M.; Schult, A.; Maass, A.; Ziegler, G.; Richardson-Klavehn, A.; Duezel, E.; Schott, B. H.
10.1101/2020.07.27.220871 — neuroscience — Posted on 2020-08-18
1907 Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS- S and MERS-S pseudotyped particles
Chen, C. Z.; Xu, M.; Pradhan, M.; Gorshkov, K.; Petersen, J.; Straus, M. R.; Zhu, W.; Shinn, P.; Guo, H.; Shen, M.; Klumpp-Thomas, C.; Michael, S. G.; Zimmerberg, J.; Zheng, W.; Whittaker, G. R.
10.1101/2020.07.10.197988 — pharmacology and toxicology — Posted on 2020-08-18
1908 Quantifying the Influence of Mutation Detection on Tumour Subclonal Reconstruction
Liu, L. Y.; Bhandari, V.; Salcedo, A.; Espiritu, S. M.; Morris, Q. D.; Kislinger, T. R.; Boutros, P. C.
10.1101/418780 — cancer biology — Posted on 2020-08-18
1909 Viral integration transforms chromatin to drive oncogenesis
Karimzadeh, M.; Arlidge, C.; Rostami, A.; Lupien, M.; Bratman, S. V.; Hoffman, M. M.
10.1101/2020.02.12.942755 — cancer biology — Posted on 2020-08-18
1913 Diversification of mammalian deltaviruses by host shifting
Bergner, L.; Orton, R.; Broos, A.; Tello, C.; Becker, D.; Carrera, J.; Patel, A.; Biek, R.; Streicker, D.
10.1101/2020.06.17.156745 — evolutionary biology — Posted on 2020-08-18
1914 Adaptive divergence generates distinct plastic responses in two closely related Senecio species
Walter, G. M.; Clark, J.; Cristaudo, A.; Nevado, B.; Catara, S.; Paunov, M.; Velikova, V.; Filatov, D.; Cozzolino, S.; Hiscock, S.; Bridle, J. R.
10.1101/2020.01.24.918201 — evolutionary biology — Posted on 2020-08-18
1915 Thyroid hormone regulates proximodistal identity in the fin skeleton
Hu, Y.; Harper, M. A.; Acosta, B.; Donahue, J.; Bui, H.; Lee, H.; Nguyen, S.; McMenamin, S.
10.1101/2020.08.18.256354 — developmental biology — Posted on 2020-08-18
1918 A novel copper-sensing two-component system for activating Dsb genes in bacteria
Yu, L.; Cao, Q.; Chen, W.; Yang, N.; Yang, C.-G.; Ji, Q.; Wu, M.; Bae, T.; Lan, L.
10.1101/2020.08.17.255257 — microbiology — Posted on 2020-08-18
1919 Evaluation of pneumococcal serotyping in nasopharyngeal carriage isolates by latex agglutination, whole genome sequencing (PneumoCaT) and DNA microarray in a high pneumococcal carriage prevalence population in Malawi
Swarthout, T. D.; Gori, A.; Bar-Zeev, N.; Kamng'ona, A. W.; Mwalukomo, T. S.; Bonomali, F.; Nyirenda, R.; Brown, C.; Msefula, J.; Everett, D.; Mwansambo, C.; Gould, K.; Hinds, J.; Heyderman, R.; French, N.
10.1101/2020.08.17.255224 — microbiology — Posted on 2020-08-18
1920 SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2
Heaton, B. E.; Trimarco, J. D.; Hamele, C. E.; Harding, A. T.; Tata, A.; Zhu, X.; Tata, P. R.; Smith, C. M.; Heaton, N. S.
10.1101/2020.08.14.251207 — microbiology — Posted on 2020-08-18
1922 MECP2 DEFICIENCY ALTERS M1/M2 GENE EXPRESSION IN BONE MARROW-DERIVED MACROPHAGES UPON STIMULATION
Zalosnik, M. I.; De Filippis, B.; De Simone, R.; Pietraforte, D.; Laviola, G.; Degano, A. L.
10.1101/2020.08.18.256313 — immunology — Posted on 2020-08-18
1923 Retinal optic flow during natural locomotion
Matthis, J. S.; Muller, K. S.; Bonnen, K. L.; Hayhoe, M. M.
10.1101/2020.07.23.217893 — neuroscience — Posted on 2020-08-18
1926 Convergent network effects along the axis of gene expression during prostate cancer progression
Charmpi, K.; Guo, T.; Zhong, Q.; Wagner, U.; Sun, R.; Toussaint, N. C.; Fritz, C.; Yuan, C.; Chen, H.; Rupp, N. J.; Christiansen, A.; Rutishauser, D.; Ruschoff, J. H.; Fankhauser, C.; Saba, K.; Poyet, C.; Hermanns, T.; Oehl, K.; Moore, A. L.; Beisel, C.; Calzone, L.; MARTIGNETTI, L.; Zhang, Q.; Zhu, Y. J.; Martinez, M. R.; Manica, M.; Haffner, M. C.; Aebersold, R.; Wild, P. J.; Beyer, A.
10.1101/2020.02.16.950378 — systems biology — Posted on 2020-08-18
1927 A mesoscopic simulator to uncover heterogeneity and evolutionary dynamics in tumors
Jimenez-Sanchez, J.; Martinez-Rubio, A.; Popov, A.; Perez-Beteta, J.; Azimzade, Y.; Molina-Garcia, D.; Belmonte-Beitia, J.; Calvo, G. F.; Perez-Garcia, V. M.
10.1101/2020.08.18.255422 — systems biology — Posted on 2020-08-18
1928 De Novo Designed Peptide and Protein Hairpins Self-assemble into Sheets and Nanoparticles.
Galloway, J. M.; Bray, H. E. V.; Shoemark, D. K.; Hodgson, L. R.; Coombs, J.; Mantell, J. M.; Rose, R. S.; Ross, J. F.; Morris, C.; Harniman, R. L.; Wood, C. W.; Arthur, C.; Verkade, P.; Woolfson, D. N.
10.1101/2020.08.14.251462 — synthetic biology — Posted on 2020-08-18
1929 Action potentials induce biomagnetic fields in Venus flytrap plants
Fabricant, A.; Iwata, G. Z.; Scherzer, S.; Bougas, L.; Rolfs, K.; Jodko-Władzinska, A.; Voigt, J.; Hedrich, R.; Budker, D.
10.1101/2020.08.12.247924 — plant biology — Posted on 2020-08-18
1933 Structure-function properties in disordered condensates
Bhandari, K.; Cotten, M. A.; Kim, J.; Rosen, M. K.; Schmit, J. D.
10.1101/2020.05.14.096388 — biophysics — Posted on 2020-08-18
1936 Role of necroptosis in chronic hepatic inflammation and liver disease in Cu/Zn superoxide dismutase deficient mice
Mohammed, S.; Nicklas, E. H.; Thadathil, N.; Selvarani, R.; Royce, G. H.; Richardson, A.; Deepa, S. S.
10.1101/2020.08.17.254888 — biochemistry — Posted on 2020-08-18
1937 Respiratory complex and tissue lineage drive mutational patterns in the tumor mitochondrial genome
Gorelick, A. N.; Kim, M.; Chatila, W. K.; La, K.; Hakimi, A. A.; Taylor, B. S.; Gammage, P. A.; Reznik, E.
10.1101/2020.08.18.256362 — genomics — Posted on 2020-08-18
1938 Bayesian inference associates rare KDR variants with specific phenotypes in pulmonary arterial hypertension
Swietlik, E. M.; Greene, D.; Zhu, N.; Megy, K.; Cogliano, M.; Rajaram, S.; Pandya, D.; Tilly, T.; Lutz, K. A.; Welch, C. C. L.; Pauciulo, M. W.; Southgate, L.; Martin, J. M.; Treacy, C. M.; Penkett, C. J.; Stephens, J. C.; UK National Cohort Study of Idiopathic and Heritable PAH, ; NIHR Bioresource for Translational Research - Rare Diseases, ; US PAH Biobank Enrolling Centers' Investigators, ; Lawrie, A.; Wilkins, M. R.; Trembath, R. C.; Shen, Y.; Wendy, C. K.; Swift, A. J.; Nichols, W. C.; Morrell, N. W.; Gräf, S.
10.1101/2019.12.11.871210 — genetics — Posted on 2020-08-18
1939 Homozygote loss-of-function variants in the human COCH gene underlie hearing loss
Danial-Farran, N.; Chervinsky, E.; Nadar-Ponniah, P. T.; Cohen Barak, E.; Taiber, S.; Khayat, M.; Avraham, K. B.; Shalev, S. A.
10.1101/2020.06.29.178053 — genetics — Posted on 2020-08-18
1940 Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities
Mallard, T. T.; Karlsson Linner, R.; Grotzinger, A. D.; Sanchez-Roige, S.; Seidlitz, J.; Okbay, A.; de Vlaming, R.; Meddens, S. F. W.; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, ; Palmer, A. A.; Davis, L. K.; Tucker-Drob, E. M.; Kendler, K.; Keller, M. C.; Koellinger, P. D.; Harden, K. P.
10.1101/603134 — genetics — Posted on 2020-08-18
1945 Differential Effects of SUMO1/2 on Circadian Protein PER2 Stability and Function
Chen, L.-C.; Hsieh, Y.-L.; Kuo, T.-Y.; Chou, Y.-C.; Hsu, P.-H.; Hwang-Verslues, W. W.
10.1101/789222 — molecular biology — Posted on 2020-08-18
1946 Seeding of outbreaks of COVID-19 by contaminated fresh and frozen food
Fisher, D.; Reilly, A.; Kang Eng Zheng, A.; Cook, A. R.; Anderson, D.
10.1101/2020.08.17.255166 — microbiology — Posted on 2020-08-18
1948 Bcr-Abl tyrosine kinase inhibitor imatinib as a potential drug for COVID-19
Mulgaonkar, N. S.; Wang, H.; Mallawarachchi, S.; Ruzek, D.; Martina, B.; Fernando, S.
10.1101/2020.06.18.158196 — microbiology — Posted on 2020-08-18
1949 SARS-CoV-2 Infection and Transmission Depends on Heparan Sulfates and Is Blocked by Low Molecular Weight Heparins
Bermejo-Jambrina, M.; Eder, J.; Kaptein, T. M.; Helgers, L. C.; Brouwer, P. J.; van Hamme, J. L.; Vlaar, A. P.; van Baarle, F. E. H. P.; de Bree, G. J.; Nijmeijer, B. M.; Kootstra, N. A.; van Gils, M. J.; Sanders, R. W.; Geijtenbeek, T. B. H.
10.1101/2020.08.18.255810 — immunology — Posted on 2020-08-18
1950 SARS-Cov-2-, HIV-1-, Ebola-neutralizing and anti-PD1 clones are predisposed
Zhang, Y.; Xu, Q.; Zeng, H.; Wang, M.; Zhang, Y.; Lan, C.; Yang, X.; Zhu, Y.; Chen, Y.; Wang, Q.; Tang, H.; Zhang, Y.; Wu, J.; Wang, C.; Xie, W.; Ma, C.; Guan, J.; Guo, S.; Chen, S.; Chang, C.; Yang, W.; Wei, L.; Ren, J.; Yu, X.; Zhang, Z.
10.1101/2020.08.13.249086 — immunology — Posted on 2020-08-18
1951 Inflammation in Alzheimer's disease: do sex and APOE matter?
Duarte-Guterman, P.; Albert, A. Y.; Inkster, A. M.; Barha, C. K.; Galea, L.
10.1101/741777 — neuroscience — Posted on 2020-08-18
1953 Membrane bending by protein phase separation
Yuan, F.; Alimohamadi, H.; Bakka, B.; Trementozzi, A. N.; Fawzi, N. L.; Rangamani, P.; Stachowiak, J. C.
10.1101/2020.05.21.109751 — biophysics — Posted on 2020-08-18
1954 Spike protein mutational landscape in India: Could Mullers ratchet be a future game-changer for COVID-19?
Banerjee, R.; Basak, K.; Ghosh, A.; Rajachandran, V.; Sureka, K.; Ganguly, D.; Chattopadhyay, S.
10.1101/2020.08.18.255570 — bioinformatics — Posted on 2020-08-18
1955 Generalized linear models provide a measure of virulence for specific mutations in SARS-CoV-2 strains
Oulas, A.; Zanti, M.; Tomazou, M.; Zachariou, M.; Minadakis, G.; Bourdakou, M. M.; Pavlidis, P.; Spyrou, G. M.
10.1101/2020.08.17.253484 — bioinformatics — Posted on 2020-08-18
1956 The effect of whey protein on viral infection and replication of SARS-CoV-2 and pangolin coronavirus in vitro
Fan, H.; Luo, Y.; Hong, B.; Wang, L.; Jin, X.; Chen, Y.; Hu, Y.; Li, T.; Zhuang, H.; Zhou, Y.-H.; Tong, Y.-G.; Xiang, K.
10.1101/2020.08.17.254979 — microbiology — Posted on 2020-08-18
1958 IFITM proteins promote SARS-CoV-2 infection in human lung cells
Prelli Bozzo, C.; Nchioua, R.; Volcic, M.; Wettstein, L.; Weil, T.; Krueger, J.; Heller, S.; Conzelmann, C.; Mueller, J. A.; Gross, R.; Zech, F.; Schuetz, D.; Koepke, L.; Stuerzel, C. M.; Schueler, C.; Stenzel, S.; Braun, E.; Weiss, J.; Sauter, D.; Muench, J.; Stenger, S.; Sato, K.; Kleger, A.; Goffinet, C.; Sparrer, K. M. J.; Kirchhoff, F.
10.1101/2020.08.18.255935 — microbiology — Posted on 2020-08-18
1959 Machine learning optimization of peptides for presentation by class II MHCs
Dai, Z.; Huisman, B. D.; Zeng, H.; Carter, B.; Jain, S.; Birnbaum, M. E.; Gifford, D. K.
10.1101/2020.08.18.256081 — immunology — Posted on 2020-08-18
1963 Fitting side-chain NMR relaxation data using molecular simulations
Kümmerer, F.; Orioli, S.; Harding-Larsen, D.; Hoffmann, F.; Gavrilov, Y.; Teilum, K.; Lindorff-Larsen, K.
10.1101/2020.08.18.256024 — biophysics — Posted on 2020-08-18
1968 A thermal trade-off between viral production and degradation drives phytoplankton-virus population dynamics
Demory, D.; Weitz, J.; Baudoux, A.-C.; Touzeau, S.; Simon, N.; Ranbouille, S.; Sciandra, A.; Bernard, O.
10.1101/2020.08.18.256156 — ecology — Posted on 2020-08-18
1969 Modelling early thermal injury using an ex vivo human skin model of contact burns
Liu, A.; Ocotl, E.; Karim, A.; Wolf, J. J.; Cox, B. L.; Eliceiri, K. W.; Gibson, A.
10.1101/2020.08.18.254458 — cell biology — Posted on 2020-08-18
1970 Detection of 'relict' western lineage of citrus tristeza virus virulent genotype in declining Arunachal Wakro orange
Datta, S.; Das, B.; Budhauliya, R.; Gopalakrishnan, R.; Muaka, V.; Meghvansi, M. K.; Rahman, S.; Dwivedi, S. K.; Veer, V.
10.1101/2020.08.18.255943 — microbiology — Posted on 2020-08-18
1971 Unique roles of vaginal Megasphaera phylotypes in reproductive health
Glascock, A. L.; Jimenez, N. R.; Boundy, S.; Koparde, V. N.; Brooks, J. P.; Edwards, D. J.; Strauss, J. F.; Jefferson, K. K.; Serrano, M. G.; Buck, G. A.; Vaginal Microbiome Consortium, ; Fettweis, J. M.
10.1101/2020.08.18.246819 — microbiology — Posted on 2020-08-18
1972 Intracellular accumulation and secretion of hydrophobin-enriched vesicles aid the rapid sporulation of molds
Cai, F.; Zhao, Z.; Gao, R.; Ding, M.; Jiang, S.; Gao, Q.; Chnthamara, K.; Grujic, M.; Fu, Z.; Zhang, J.; Przylucka, A.; Xu, P.; Bayram Akcapinar, G.; Shen, Q.; Druzhinina, I.
10.1101/2020.08.18.255406 — microbiology — Posted on 2020-08-18
1973 A Lymph Node Targeted Amphiphile Vaccine Induces Potent Cellular and Humoral Immunity to SARS-CoV-2
Steinbuck, M. P.; Seenappa, L. M.; Jakubowski, A.; McNeil, L. K.; Haqq, C. M.; DeMuth, P. C.
10.1101/2020.08.17.251728 — immunology — Posted on 2020-08-18
1974 Erythroid precursors and progenitors suppress adaptive immunity and get invaded by SARS-CoV-2
Shahbaz, S.; Xu, L.; Osman, M.; Sligl, W.; Shields, J.; Joyce, M.; Tyrrell, L.; Oyegbami, O.; Elahi, S.
10.1101/2020.08.18.255927 — immunology — Posted on 2020-08-18
1979 Atypical genomic patterning of the cerebral cortex in autism with poor early language outcome
Lombardo, M. V.; Eyler, L.; Pramparo, T.; Gazestani, V. H.; Hagler, D. J.; Chen, C.-H.; Dale, A. M.; Seidlitz, J.; Bethlehem, R. A. I.; Bertelsen, N.; Carter Barnes, C.; Lopez, L.; Campbell, K.; Lewis, N. E.; Pierce, K.; Courchesne, E.
10.1101/2020.08.18.253443 — neuroscience — Posted on 2020-08-18
1981 Evidence for genetically distinct direct and indirect spinocerebellar pathways mediating proprioception.
Pop, I. V.; Espinosa-Becerra, F.; Goyal, M.; Mona, B.; Landy, M.; Ogujiofor, O.; Dean, K. M.; Gurumurthy, C. M.; Lai, H. C.
10.1101/2020.08.17.254607 — neuroscience — Posted on 2020-08-18
1983 Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum
Cochet-Escartin, O.; Demircigil, M.; Hirose, S.; Allais, B.; Calvez, V.; Funamoto, K.; Rieu, J.-P.
10.1101/2020.08.17.246082 — biophysics — Posted on 2020-08-18
1986 KG-COVID-19: a framework to produce customized knowledge graphs for COVID-19 response
Reese, J. T.; Unni, D. R.; Callahan, T. J.; Cappelletti, L.; Ravanmehr, V.; Carbon, S.; Fontana, T.; Blau, H.; Matentzoglu, N.; Harris, N. L.; Munoz-Torres, M. C.; Robinson, P. N.; Joachimiak, M. P.; Mungall, C. J.
10.1101/2020.08.17.254839 — bioinformatics — Posted on 2020-08-18
1987 GATA4 regulates epithelial morphogenesis in the developing mouse stomach to promote establishment of a glandular columnar epithelium
DeLaForest, A.; Kohlnhofer, B. M.; Franklin, O. D.; Stavniichuk, R.; Thompson, C. A.; Pulakanti, K.; Rao, S.; Battle, M. A.
10.1101/2020.08.18.251587 — developmental biology — Posted on 2020-08-18
1989 Bacterial modification of the host glycosaminoglycan heparan sulfate modulates SARS-CoV-2 infectivity
Martino, C.; Kellman, B. P.; Sandoval, D. R.; Clausen, T. M.; Marotz, C. A.; Song, S. J.; Wandro, S.; Zaramela, L. S.; Salido Benitez, R. A.; Zhu, Q.; Armingol, E.; Vazquez-Baeza, Y.; McDonald, D.; Sorrentino, J. T.; Taylor, B.; Belda-Ferre, P.; Liang, C.; Zhang, Y.; Schifanella, L.; Klatt, N. R.; Havulinna, A. S.; Jousilahti, P.; Huang, S.; Haiminen, N.; Parida, L.; Kim, H.-C.; Swafford, A. D.; Zengler, K.; Cheng, S.; Inouye, M.; Niiranen, T.; Jain, M.; Salomaa, V.; Esko, J. D.; Lewis, N. E.; Knight, R.
10.1101/2020.08.17.238444 — microbiology — Posted on 2020-08-18
1990 Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2
Chen, C. Z.; Shinn, P.; Itkin, Z.; Eastman, R.; Bostwick, R.; Rasmussen, L.; Huang, R.; Shen, M.; Hu, X.; Wilson, K. M.; Brooks, B.; Guo, H.; Zhao, T.; Klumpp-Thomas, C.; Simeonov, A.; Michael, S. G.; Lo, D. C.; Hall, M.; Zheng, W.
10.1101/2020.08.18.255877 — microbiology — Posted on 2020-08-18
1991 Equine hyperimmune globulin raised against the SARS-CoV-2 spike glycoprotein has extremely high neutralizing titers
Cunha, L. E. R.; Stolet, A. A.; Strauch, M. A.; Pereira, V. A. R.; Dumard, C. H.; Souza, P. N. C.; Fonseca, J. G.; Pontes, F. E.; Meirelles, L. G. R.; Albuquerque, J. W. M.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Lima, T. M.; Alvim, R. G. F.; Zingali, R.; Oliveira, G. A. P.; Souza, T. M. L.; TANURI, A.; Gomes, A. M. O.; Oliveira, A. C.; Guedes, H. L. M.; Castilho, L. R.; Silva, J. L.
10.1101/2020.08.17.254375 — immunology — Posted on 2020-08-18
1992 Bayesian Structural Time Series for Biomedical Sensor Data: A Flexible Modeling Framework for Evaluating Interventions
Liu, J.; Spakowicz, D. J.; Ash, G. I.; Hoyd, R.; Zhang, A.; Lou, S.; Lee, D.; Zhang, J.; Presley, C.; Greene, A.; Stults-Kolehmainen, M.; Nally, L.; Baker, J. S.; Fucito, L. M.; Weinzimer, S. A.; Papachristos, A. V.; Gerstein, M.
10.1101/2020.03.02.973677 — bioinformatics — Posted on 2020-08-18
1993 Revealing the polarity of actin filaments by cryo-electron tomography
Martins, B.; Sorrentino, S.; Chung, W.-L.; Tatli, M.; Medalia, O.; Eibauer, M.
10.1101/2020.03.11.987263 — cell biology — Posted on 2020-08-18
1995 Normothermic Ex-vivo Kidney Perfusion in a Porcine Auto-Transplantation Model Preserves the Expression of Key Mitochondrial Proteins: An Unbiased Proteomics Analysis
McEvoy, C. M.; Clotet-Freixas, S.; Tokar, T.; Pastrello, C.; Reid, S.; Batruch, I.; RaoPeters, A. A. E.; Kaths, J. M.; Urbanellis, P.; Farkona, S.; Van, J. A. D.; Urquhart, B. L.; John, R.; Jurisica, I.; Robinson, L.; Selzner, M.; Konvalinka, A.
10.1101/2020.08.17.253252 — molecular biology — Posted on 2020-08-18
1998 Invasive freshwater snails form novel microbial relationships
Bankers, L.; Dahan, D.; Neiman, M.; Adrian-Tucci, C.; Frost, C.; Hurst, G.; King, K.
10.1101/2020.04.29.069013 — evolutionary biology — Posted on 2020-08-18
2000 Extracellular signal-regulated kinase (ERK) pathway control of CD8+ T cell differentiation
Damasio, M. P.; Marchingo, J. M.; Spinelli, L.; Cantrell, D. A.; Howden, A. J.
10.1101/2020.08.18.255711 — immunology — Posted on 2020-08-18
2004 Probing the Hidden Sensitivity of Intrinsically Disordered Proteins to their Chemical Environment
Moses, D.; Yu, F.; Ginell, G.; Shamoon, N. M.; Koenig, P. S.; Holehouse, A. S.; Sukenik, S.
10.1101/2020.08.17.252478 — biophysics — Posted on 2020-08-18
2007 Spatial scaling of pollen-based alpha and beta diversity within forest and open landscapes of Central Europe
Abraham, V.; Rolecek, J.; Vild, O.; Jamrichova, E.; Pleskova, Z.; Werchan, B.; Svitavska Svobodova, H.; Kunes, P.
10.1101/2020.08.18.255737 — ecology — Posted on 2020-08-18
2013 Quantitative phosphoproteomics uncovers dysregulated kinase networks in Alzheimer's disease
Morshed, N.; Lee, M.; Rodriguez, F. H.; Lauffenburger, D. A.; Mastroeni, D.; White, F.
10.1101/2020.08.18.255778 — neuroscience — Posted on 2020-08-18
2015 Control and regulation of acetate overflow in Escherichia coli
Millard, P.; Enjalbert, B.; Uttenweiler-Joseph, S.; Portais, J.-C.; Letisse, F.
10.1101/2020.08.18.255356 — systems biology — Posted on 2020-08-18
2016 Selective Elimination of Osteosarcoma Cell Lines with Short Telomeres by ATR Inhibitors
Goncalves, T.; Zoumpoulidou, G.; Alvarez-Mendoza, C.; Collopy, L. C.; Strauss, S. J.; Mittnacht, S.; Tomita, K.
10.1101/2020.08.18.254664 — cancer biology — Posted on 2020-08-18
2020 Applying genomic data to seagrass conservation
Nielsen, E. S.; Phair, N. L.; von der Heyden, S.
10.1101/2020.08.18.255307 — genomics — Posted on 2020-08-18
2021 In-depth analysis reveals complex molecular etiology of idiopathic cerebral palsy
Li, N.; Zhou, P.; Tang, H.; He, L.; Fang, X.; Zhao, J.; Wang, X.; Qi, Y.; Sun, C.; Lin, Y.; Qin, F.; Yang, M.; Zhang, Z.; Liao, C.; Zheng, S.; Peng, X.; Xue, T.; Zhu, Q.; Li, Y.; Liu, L.; Huang, J.; Liu, L.; Peng, C.; Han, D.; Liu, D.; Xu, K.; Hu, H.
10.1101/2020.08.17.255158 — genetics — Posted on 2020-08-18
2022 A human-specific structural variation at the ZNF558 locus controls a gene regulatory network during forebrain development
Johansson, P. A.; Brattas, P. L.; Douse, C. H.; Hsieh, P.; Pontis, J.; Grassi, D.; Garza, R.; Jonsson, M. E.; Atacho, D. A. M.; Pircs, K.; Eren, F.; Sharma, Y.; Johansson, J.; Trono, D.; Eichler, E. E.; Jakobsson, J.
10.1101/2020.08.18.255562 — genetics — Posted on 2020-08-18
2024 EMBRYONIC DEVELOPMENT OF THE FIRE-EYE-TETRA Moenkhausia oligolepis (CHARACIFORMES: CHARACIDAE)
Dos Santos, R. S.; Rodrigues, J. R.; Cordeiro, J. G.; Leite, M.; Tercya, H.; Costa, B. P. D.; Costa, R. S.; Maximino, C.; Siqueira-Silva, D. H.
10.1101/2020.08.18.255554 — developmental biology — Posted on 2020-08-18
2025 Oligomeric hypercompex of the complete oxidative phosphorylation system in heart mitochondria.
Nesterov, S. V.; Chesnokov, Y. M.; Kamyshinsky, R. A.; Panteleeva, A. A.; Lyamzaev, K. G.; Vasilov, R. G.; Yaguzhinsky, L. S.
10.1101/2020.08.17.253922 — molecular biology — Posted on 2020-08-18
2027 Characterization of Mice Bearing Humanized Androgen Receptor Genes (h/mAr) Varying in Polymorphism Length
Lindenmaier, Z.; Yee, Y.; Kinman, A.; Fernandes, D.; Ellegood, J.; Burton, C.; Robins, D.; Raznahan, A.; Arnold, P.; Lerch, J. P.
10.1101/2020.08.18.248153 — neuroscience — Posted on 2020-08-18
2028 Distinct synaptic and related transcriptional abnormalities in neonatal, childhood and mature autism model of primate: implications for early-age therapeutic intervention
Watanabe, S.; Kurotani, T.; Oga, T.; Noguchi, J.; Isoda, R.; Nakagami, A.; Sakai, K.; Nakagaki, K.; Sumida, K.; Hoshino, K.; Saito, K.; Miyawaki, I.; Sekiguchi, M.; Wada, K.; Minamimoto, T.; Ichinohe, N.
10.1101/2020.08.18.255240 — neuroscience — Posted on 2020-08-18
2029 Assessing Study Reproducibility through MMRI: A Novel Approach for Large-scale High-throughput Association Studies
Jiao, Z.; Lai, Y.; Kang, J.; Gong, W.; Ma, L.; Jia, T.; Xie, C.; Cheng, W.; Heinz, A.; Desrivieres, S.; Schumann, G.; Sun, F.; Feng, J.
10.1101/2020.08.18.253740 — neuroscience — Posted on 2020-08-18
2030 Systems vaccinology analysis of a recombinant vaccinia-based vector reveals diverse innate immune signatures at the injection site
Hazlewood, J. E.; Dumenil, T.; Le, T. T.; Slonchak, A.; Kazakoff, S. H.; Patch, A.-M.; Gray, L.-A.; Howley, P. M.; Liu, L.; Hayball, J. D.; Yan, K.; Rawle, D. J.; Prow, N. A.; Suhrbier, A.
10.1101/2020.08.17.254938 — systems biology — Posted on 2020-08-18
2031 PROFILING OF Y1 CELLS TREATED WITH FGF-2 REVEALS PARALLELS WITH ONCOGENE-INDUCED SENESCENCE
Lund, P. J.; Lopes, M.; Sidoli, S.; Coradin, M.; Vitorino, F. N. d. L.; Chagas da Cunha, J. P.; Garcia, B. A.
10.1101/2020.08.17.247023 — systems biology — Posted on 2020-08-18
2032 Oxylipin metabolism is controlled by mitochondrial b-oxidation during bacterial inflammation.
Misheva, M.; Kotzamanis, K.; Davies, L.; Tyrrell, V.; Rodrigues, P.; Benavides, G.; Christine, H.; Murphy, R.; Kennedy, P.; Taylor, P.; Rosas, M.; Jones, S.; Deshpande, S.; Andrews, R.; Czubala, M.; Gurney, M.; Aldrovandi, M.; Meckelmann, S.; Ghazal, P.; Darley-Usmar, V.; White, D.; O'Donnell, V.
10.1101/2020.08.17.252007 — biochemistry — Posted on 2020-08-18
2034 Measuring DNA mechanics on the genome scale
Basu, A.; Bobrovnikov, D. G.; Qureshi, Z.; Kayikcioglu, T.; Ngo, T. T.; Ranjan, A.; Eustermann, S.; Cieza, B.; Hejna, M.; Rube, T. H.; Hopfner, K.-P.; Wolberger, C.; Song, J. S.; Ha, T.
10.1101/2020.08.17.255042 — biophysics — Posted on 2020-08-18
2041 The Role of Colony Temperature in the Entrainment of Circadian Rhythms of Honey Bee Foragers
Giannoni Guzman, M. A.; Rivera, E.; Aleman-Rios, J.; Melendez Moreno, A. M.; Lubirel, D.; Perez Ramos, M.; Moore, D.; Giray, T.; Agosto Rivera, J. L.
10.1101/2020.08.17.254722 — animal behavior and cognition — Posted on 2020-08-18
2042 Harnessing population-specific protein truncating variants to improve the annotation of loss-of-function alleles
Skitchenko, R. K.; Kornienko, J. S.; Maksiutenko, E. M.; Glotov, A. S.; Predeus, A. V.; Barbitoff, Y. A.
10.1101/2020.08.17.254904 — genomics — Posted on 2020-08-18
2044 Super-resolution light-sheet fluorescence microscopy by SOFI.
Mizrachi, J.; Narasimhan, A.; Qi, X.; Drewes, R.; Palaniswamy, R.; Wu, Z.; Osten, P.
10.1101/2020.08.17.254797 — neuroscience — Posted on 2020-08-18
2048 Functional mapping of androgen receptor enhancer activity
Huang, C.-C. F.; Lingadahalli, S.; Morova, T.; Ozturan, D.; Hu, E.; Yu, I. P. L.; Linder, S.; Hoogstraat, M.; Stelloo, S.; Sar, F.; van der Poel, H.; Altintas, U. B.; Saffarzadeh, M.; Le Bihan, S.; McConeghy, B.; Gokbayrak, B.; Feng, F. Y.; Gleave, M. E.; Bergman, A. M.; Collins, C.; Hach, F.; Zwart, W.; Emberly, E.; Lack, N. A.
10.1101/2020.08.18.255232 — cancer biology — Posted on 2020-08-18
2054 Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family
Guo, X.; Söderholm, A.; Kanchugal P, S.; Isaksen, G. V.; Warsi, O.; Eckhard, U.; Trigüis, S.; Gogoll, A.; Jerlström-Hultqvist, J.; Aqvist, J.; Andersson, D.; Selmer, M.
10.1101/2020.08.16.253161 — biochemistry — Posted on 2020-08-18
2056 The Role of Temperature on the Development of Circadian Rhythms in Honey Bee Workers
Giannoni-Guzman, M. A.; Aleman-Rios, J.; Melendez Moreno, A. M.; Diaz Hernandez, G.; Perez Torres, M.; Lubriel, D.; Giray, T.; Agosto Rivera, J. L.
10.1101/2020.08.17.254557 — animal behavior and cognition — Posted on 2020-08-18
2059 Vector and cell-culture passaging of dengue clinical samples for virus isolation and amplification does not significantly change genome consensus or frequencies of intra-host viral variants
Fung, C.; Li, T.; Pollett, S.; Alera, M. T.; Yoon, I.-K.; Hang, J.; Macareo, L.; Srikiatkhachorn, A.; Ellison, D.; Rothman, A. L.; Fernandez, S.; Jarman, R. G.; Maljkovic Berry, I.
10.1101/2020.08.17.254417 — evolutionary biology — Posted on 2020-08-18
2060 Context-dependency in biodiversity-multifunctionality relationships is driven by nitrogen availability and plant functional composition
Pichon, N. A.; Cappelli, S. L.; Soliveres, S.; Mannall, T.; Nwe, T. Z.; Hölzel, N.; Klaus, V. H.; Kleinebecker, T.; Vincent, H.; Allan, E.
10.1101/2020.08.17.254086 — ecology — Posted on 2020-08-18
2062 Neuroimmune circuits involved in β-lactoglobulin-induced food allergy
Lemos, L.; Assis, H. C.; Alves, J. L.; Reis, D. S.; Canesso, M. C. C.; Moreira, T. G.; Sato, B. K. M.; Batista, L. A.; Lenzi, J. A. S. G.; Moraes, M. A.; Pereira, L. M.; Aguiar, D. C.; Souza, B. R.; Cara, D. C.; Gomes-Santos, A. C.; Faria, A. M. C.
10.1101/2020.08.17.248310 — immunology — Posted on 2020-08-18
2066 Causal evidence for the adaptive benefits of social foraging in the wild
Snijders, L.; Krause, S.; Tump, A. N.; Breuker, M.; Ortiz, C.; Rizzi, S.; Ramnarine, I. W.; Krause, J.; Kurvers, R. H. J. M.
10.1101/2020.08.17.254250 — animal behavior and cognition — Posted on 2020-08-18
2068 Associations of early social experience with offspring DNA methylation and later life stress phenotype
Laubach, Z. M.; Greenberg, J. R.; Turner, J. W.; Montgomery, T.; Pioon, M. O.; Smale, L.; Cavalcante, R.; Padmanabhan, K. R.; Lalancette, C.; vonHoldt, B.; Faulk, C. D.; Dolinoy, D. C.; Holekamp, K. E.; Perng, W.
10.1101/2020.08.17.254805 — animal behavior and cognition — Posted on 2020-08-18
2072 Inhibition of AlgU by MucA is required for viability in Pseudomonas aeruginosa
Schofield, M. C.; Rodriguez, D.; Kidman, A. A.; Michaels, L. A.; Campbell, E. A.; Jorth, P. A.; Tseng, B. S.
10.1101/2020.08.17.253617 — microbiology — Posted on 2020-08-18
2075 Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs
Kim, J. H.; Megquier, K. J.; Thomas, R.; Sarver, A. L.; Song, J. M.; Kim, Y. T.; Schulte, A. J.; Cheng, N.; Linden, M. A.; Murugan, P.; Oseth, L.; Foster, C. L.; Elvers, I.; Swofford, R.; Turner-Maier, J.; Karlsson, E. K.; Breen, M.; Lindblad-Toh, K.; Modiano, J. F.
10.1101/2020.08.11.246777 — cancer biology — Posted on 2020-08-17
2076 DeepEMhancer: a deep learning solution for cryo-EM volume post-processing
Sanchez Garcia, R.; Gomez-Blanco, J.; Cuervo, A.; Carazo, J. M.; Sorzano, C. O. S.; Vargas, J.
10.1101/2020.06.12.148296 — bioinformatics — Posted on 2020-08-17
2078 FLIMJ: an open-source ImageJ toolkit for fluorescence lifetime image data analysis
Gao, D. W.; Barber, P. R.; Chacko, J. V.; Kader Sagar, A.; Rueden, C. T.; Grislis, A. R.; Hiner, M.; Eliceiri, K. W.
10.1101/2020.08.17.253625 — bioengineering — Posted on 2020-08-18
2079 Consensus-based somatic variant-calling method correlates FBXW7 mutations with poor prognosis in canine B-cell lymphoma
White, M. E.; Hayward, J. J.; Hertafeld, S. R.; Castelhano, M. G.; Leung, W.; Dave, S.; Bhinder, B. H.; Elemento, O. L.; Boyko, A. R.; Richards, K. L.; Suter, S. E.
10.1101/2020.08.16.250100 — genomics — Posted on 2020-08-17
2081 Homozygote loss-of-function variants in the human COCH gene underlie hearing loss
Danial-Farran, N.; Chervinsky, E.; Nadar-Ponniah, P. T.; Cohen Barak, E.; Taiber, S.; Khayat, M.; Avraham, K. B.; Shalev, S. A.
10.1101/2020.06.29.178053 — genetics — Posted on 2020-08-17
2085 Utilizing Computational Machine Learning Tools to Understand Immunogenic Breadth in the Context of a CD8 T-Cell Mediated HIV Response
McGowan, E.; Rosenthal, R.; Fiore-Gartland, A.; Macharia, G.; Balinda, S.; Kapaata, A.; Muok, E.; Umviligihozo, G.; Dalel, J.; Streatfield, C.; Coutinho, H.; Monaco, D.; Morrison, D.; Yue, L.; Hunter, E.; Nielsen, M.; Gilmour, J.; Hare, J.
10.1101/2020.08.15.250589 — immunology — Posted on 2020-08-17
2087 Time-course transcriptome landscape of achene development in lettuce
Luo, C.; Wang, S.; Ning, K.; Chen, Z.; Yang, J.; Wang, Y.; Qi, M.; Wang, Q.
10.1101/2020.08.03.233387 — plant biology — Posted on 2020-08-17
2089 A workflow for sizing oligomeric biomolecules based on cryo single molecule localization microscopy
Schneider, M. C.; Telschow, R.; Mercier, G.; Lopez-Martinez, M.; Scherzer, O.; Schütz, G.
10.1101/2020.08.17.253567 — biophysics — Posted on 2020-08-17
2092 MRLocus: identifying causal genes mediating a trait through Bayesian estimation of allelic heterogeneity
Zhu, A.; Matoba, N.; Wilson, E.; Tapia, A. L.; Li, Y.; Ibrahim, J. G.; Stein, J. L.; Love, M. I.
10.1101/2020.08.14.250720 — bioinformatics — Posted on 2020-08-17
2093 An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation
Schoof, M.; Faust, B.; Saunders, R. A.; Sangwan, S.; Rezelj, V. V.; Hoppe, N.; Boone, M.; Billesboelle, C.; Puchades, C.; Azumaya, C. M.; Kratochvil, H. T.; Zimanyi, M.; Deshpande, I.; Liang, J.; Dickinson, S.; Nguyen, H. C.; Chio, C. M.; Merz, G. E.; Thompson, M. C.; Diwanji, D.; Schaefer, K.; Anand, A. A.; Dobzinski, N.; Zha, B. S.; Simoneau, C. R.; Leon, K.; White, K. M.; Chio, U. S.; Gupta, M.; Jin, M.; Li, F.; Liu, Y.; Zhang, K.; Bulkley, D.; Sun, M.; Smith, A. M.; Rizo, A. N.; Moss, F.; Brilot, A. F.; Pourmal, S.; Trenker, R.; Pospiech, T.; Gupta, S.; Barsi-Rhyne, B.; Belyy, V.; Barile-H
10.1101/2020.08.08.238469 — biochemistry — Posted on 2020-08-17
2096 Interspecies variation in hominid gut microbiota controls host gene regulation
Muehlbauer, A. L.; Richards, A. L.; Alazizi, A.; Burns, M.; Gomez, A.; Clayton, J. B.; Petrzelkova, K.; Cascardo, C.; Resztak, J.; Wen, X.; Pique-Regi, R.; Luca, F.; Blekhman, R.
10.1101/2020.08.17.255059 — genomics — Posted on 2020-08-17
2097 Spotting genome-wide pigmentation variation in a brown trout admixture context
VALETTE, T.; LEITWEIN, M.; LASCAUX, J.-M.; DESMARAIS, E.; BERREBI, P.; GUINAND, B.
10.1101/2020.07.23.217109 — evolutionary biology — Posted on 2020-08-17
2099 Plasmodium DEH is crucial for oocyst mitotic division but not cell size during malaria transmission
Guttery, D. S.; Pandey, R.; Ferguson, D.; Wall, R.; Brady, D.; Gupta, D.; Holder, A. A.; Tewari, R.
10.1101/2020.07.01.182774 — cell biology — Posted on 2020-08-17
2102 Single-Strand DNA Breaks Cause Replisome Disassembly
Vrtis, K.; Dewar, J.; Chistol, G.; Wu, A.; Graham, T.; Walter, J.
10.1101/2020.08.17.254235 — molecular biology — Posted on 2020-08-17
2104 Transcriptomic profiling of human corona virus (HCoV)-229E -infected human cells and genomic mutational analysis of HCoV-229E and SARS-CoV-2
Friedman, N.; Jacob-Hirsch, J.; Drori, Y.; Eyal, E.; Kol, N.; Nayshool, O.; Mendelson, E.; Rechavi, G.; Mandelboim, M.
10.1101/2020.08.17.253682 — microbiology — Posted on 2020-08-17
2105 Pleiotropic effect of Lactoferrin in the prevention and treatment of COVID-19 infection:randomized clinical trial, in vitro and in silico preliminary evidences
Campione, E.; Lanna, C.; Cosio, T.; Rosa, L.; Conte, M. P.; Iacovelli, F.; Romeo, A.; Falconi, M.; Del Vecchio, C.; Franchin, E.; Lia, M. S.; Minieri, M.; Chiaramonte, C.; Ciotti, M.; Nuccetelli, M.; Terrinoni, A.; Iannuzzi, I.; Coppeda, L.; Magrini, A.; Moricca, N.; Sabatini, S.; Rosapepe, F.; Bartoletti, P. L.; Bernardini, S.; Andreoni, M.; Valenti, P.; Bianchi, L.
10.1101/2020.08.11.244996 — microbiology — Posted on 2020-08-17
2106 DPP9 directly sequesters the NLRP1 C-terminus to repress inflammasome activation
Hollingsworth, L. R.; Sharif, H.; Griswold, A. R.; Fontana, P.; Mintseris, J.; Dagbay, K. B.; Paulo, J. A.; Gygi, S. P.; Bachovchin, D. A.; Wu, H.
10.1101/2020.08.14.246132 — immunology — Posted on 2020-08-17
2108 Multiple regions of primate orofacial sensorimotor cortex encode bite force and gape
Arce-McShane, F. I.; Sessle, B. J.; Ram, Y.; Balcer, C. A.; Ross, C. F.; Hatsopoulos, N. G.
10.1101/2020.08.16.252817 — neuroscience — Posted on 2020-08-17
2110 DNA methylation across the genome in aged human skeletal muscle tissue and stem cells: The role of HOX genes and physical activity
Turner, D. C.; Gorski, P. P.; Maasar, M. F.; Seaborne, R. A.; Baumert, P.; Brown, A. D.; Kitchen, M. O.; Erskine, R. M.; Dos-Remedios, I.; Voisin, S.; Eynon, N.; Sultanov, R. I.; Borisov, O. V.; Larin, A. K.; Semenova, E. A.; Popov, D. V.; Generozov, E. V.; Stewart, C. E.; Drust, B.; Owens, D. J.; Ahmetov, I. I.; Sharples, A. P.
10.1101/2019.12.27.886135 — physiology — Posted on 2020-08-17
2111 Multi-environment phenotyping of C. elegans for robust evaluation of physical performance
Hewitt, J. E.; Laranjeiro, R.; Norouzi, M.; Ellwood, R.; Antebi, A.; Szewczyk, N. J.; Driscoll, M.; Vanapalli, S. A.
10.1101/2020.08.17.253583 — physiology — Posted on 2020-08-17
2113 The immune landscape of primary central nervous system diffuse large B cell lymphoma
Alame, M.; Cornillot, E.; Cacheux, V.; Rigau, V.; Costes-Martineau, V.; Lacheretz-Szablewski, V.; Colinge, J.
10.1101/2020.08.17.254284 — cancer biology — Posted on 2020-08-17
2114 Promoterless Transposon Mutagenesis Drives Solid Cancers via Tumor Suppressor Inactivation
Aiderus, A.; Contreras-Sandoval, A. M.; Meshey, A. L.; Newberg, J. Y.; Ward, J. M.; Swing, D.; Copeland, N. G.; Jenkins, N. A.; Mann, K. M.; Mann, M. B.
10.1101/2020.08.17.254565 — cancer biology — Posted on 2020-08-17
2115 Precision combination therapies based on recurrent oncogenic co-alterations
Li, X.; Dowling, E.; Yan, G.; Bozorgui, B.; Imanirad, P.; Elnaggar, J. H.; Luna, A.; Sander, C.; Korkut, A.
10.1101/2020.06.03.132514 — cancer biology — Posted on 2020-08-17
2120 Modern Hopfield Networks and Attention for Immune Repertoire Classification
Widrich, M.; Schäfl, B.; Pavlovic, M.; Ramsauer, H.; Gruber, L.; Holzleitner, M.; Brandstetter, J.; Sandve, G. K.; Greiff, V.; Hochreiter, S.; Klambauer, G.
10.1101/2020.04.12.038158 — bioinformatics — Posted on 2020-08-17
2121 ZeroCostDL4Mic: an open platform to use Deep-Learning in Microscopy
Chamier, L. v.; Laine, R. F.; Jukkala, J.; Spahn, C.; Krentzel, D.; Nehme, E.; Lerche, M.; Hernandez-perez, S.; Mattila, P.; Karinou, E.; Holden, S.; Can Solak, A.; Krull, A.; Buchholz, T.-O.; Jones, M. L.; Royer, L. A.; Leterrier, C.; Shechtman, Y.; Jug, F.; Heilemann, M.; Jacquemet, G.; Henriques, R.
10.1101/2020.03.20.000133 — bioinformatics — Posted on 2020-08-17
2122 Functional and structural characterization of allosteric activation of Phospholipase Cϵ by Rap1A
Sieng, M.; Selvia, A. F.; Garland-Kuntz, E. E.; Hopkins, J. B.; Fisher, I. J.; Marti, A. T.; Lyon, A.
10.1101/2020.07.10.191643 — biochemistry — Posted on 2020-08-17
2123 Acoustic niche partitioning in two tropical wet forest bird communities
Hart, P. J.; Paxton, K.; Ibanez, T.; Tredinnick, G.; Sebastian-Gonzalez, E.; Tanimoto-Johnson, A.
10.1101/2020.08.17.253674 — animal behavior and cognition — Posted on 2020-08-17
2126 Genetic diversity of maize landraces from the South-West of France
Diaw, Y.; Tollon-Cordet, C.; Charcosset, A.; Nicolas, S. D.; Madur, D.; Ronfort, J.; David, J.; Gouesnard, B.
10.1101/2020.08.17.253690 — genetics — Posted on 2020-08-17
2129 P-elements strengthen reproductive isolation within the Drosophila simulans species complex
Serrato-Capuchina, A.; D'Agostino, E. R. R.; Peede, D.; Roy, B.; Isbell, K.; Wang, J.; Matute, D. R.
10.1101/2020.08.17.254169 — evolutionary biology — Posted on 2020-08-17
2130 The dynamics of spawning acts by a semelparous fish and its associated energetic expenses
Tentelier, C.; Bouchard, C.; Bernardin, A.; Tauzin, A.; Aymes, J.-C.; Lange, F.; Recapet, C.; Rives, J.
10.1101/436295 — ecology — Posted on 2020-08-17
2131 Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis
Okuda, K.; Keyser, M.; Gurevich, D. B.; Sturtzel, C.; Paterson, S.; Chen, H.; Scott, M.; Condon, N.; Martin, P. B.; Distel, M.; Hogan, B. M.
10.1101/2020.08.17.254912 — developmental biology — Posted on 2020-08-17
2132 Cleavage Site Specificity for Processing of Farnesylated Prelamin A by the Zinc Metalloprotease ZMPSTE24
Babatz, T. D.; Spear, E. D.; Xu, W.; Sun, O. L.; Nie, L.; Carpenter, E. P.; Michaelis, S.
10.1101/2020.08.17.254532 — cell biology — Posted on 2020-08-17
2134 Bone Marrow Stromal Cells in a Mouse Model of Implant Osseointegration
Vesprey, A.; Suh, E. S.; Goz Ayturk, D.; Yang, X.; Rogers, M.; Sosa, B.; Niu, Y.; Kalajzic, I.; Ivashkiv, L. B.; Bostrom, M. P. G.; Ayturk, U. M.
10.1101/2020.08.17.254433 — cell biology — Posted on 2020-08-17
2137 Discovery of a microbially produced small molecule in a host-specific organ
Zink, K. E.; Tarnowski, D. A.; Lazzara, P. M.; Moore, T. W.; Mandel, M. J.; Sanchez, L.
10.1101/2020.08.17.254854 — microbiology — Posted on 2020-08-17
2139 No metabolic "default mode" of human brain function
Jonasson, L. S.; Grill, F.; Hahn, A.; Rischka, L.; Lanzenberger, R.; Panes Lundmark, V.; Riklund, K.; Axelsson, J.; Rieckmann, A.
10.1101/2020.08.17.245183 — neuroscience — Posted on 2020-08-17
2142 Critical role of the periplasm in copper homeostasis in Gram-negative bacteria
Ishihara, J.-i.; Mekubo, T.; Kusaka, C.; Kondo, S.; Aiba, H.; Ishikawa, S.; Ogasawara, N.; Oshima, T.; Takahashi, H.
10.1101/2020.08.17.251918 — systems biology — Posted on 2020-08-17
2143 Baculovirus-vectored precision delivery of large DNA cargoes in human genomes
Aulicino, F.; Pelosse, M.; Toelzer, C.; Capin, J.; Meysami, P.; Dillingham, M. S.; Schaffitzel, C.; Berger, I.
10.1101/2020.08.17.253898 — synthetic biology — Posted on 2020-08-17
2145 Vesicle capture by discrete self-assembled clusters of membrane-bound Munc13
Li, F.; Sundaram, V. K.; Gatta, A. T.; Coleman, J.; Krishnakumar, S.; Pincet, F.; Rothman, J. E.
10.1101/2020.08.17.254821 — biochemistry — Posted on 2020-08-17
2147 SARS-Cov-2-, HIV-1-, Ebola-neutralizing and anti-PD1 clones are predisposed
Zhang, Y.; Xu, Q.; Zeng, H.; Wang, M.; Zhang, Y.; Lan, C.; Yang, X.; Zhu, Y.; Chen, Y.; Wang, Q.; Tang, H.; Zhang, Y.; Wu, J.; Wang, C.; Xie, W.; Ma, C.; Guan, J.; Guo, S.; Chen, S.; Chang, C.; Yang, W.; Wei, L.; Ren, J.; Yu, X.; Zhang, Z.
10.1101/2020.08.13.249086 — immunology — Posted on 2020-08-17
2149 SnapATAC: A Comprehensive Analysis Package for Single Cell ATAC-seq
Fang, R.; Preissl, S.; Hou, X.; Lucero, J.; Wang, X.; Motamedi, A.; Shiau, A. K.; Mukamel, E. A.; Zhang, Y.; Behrens, M. M.; Ecker, J.; Ren, B.
10.1101/615179 — bioinformatics — Posted on 2020-08-17
2154 Quantitative profiling of microbial communities by de novo metaproteomics
Kleikamp, H. B. C.; Pronk, M.; Tugui, C.; Guedes da Silva, L.; Abbas, B.; Lin, Y. M.; van Loosdrecht, M. C. M.; Pabst, M.
10.1101/2020.08.16.252924 — systems biology — Posted on 2020-08-17
2161 A Novel Stress Response Pathway Regulates Ribosome Biogenesis
Szaflarski, W.; Sowinski, M.; Lesniczak, M.; Ojha, S.; Aulas, A.; Dave, D.; Malla, S.; Anderson, P.; Ivanov, P.; Lyons, S. M.
10.1101/2020.08.16.250183 — biochemistry — Posted on 2020-08-17
2165 Illegal hunting threatens the establishment of a lynx population and highlights the need of a centralized judiciary approach
Arlettaz, R.; Chapron, G.; Kery, M.; Klaus, E.; Mettaz, S.; Vignali, S.; Zimmermann, F.; Braunisch, V.
10.1101/2020.08.16.252890 — ecology — Posted on 2020-08-17
2166 An invasive plant species enhances biodiversity in overgrazed pastures but inhibits its recovery in protected areas
Losapio, G. L.; De Moraes, C. M.; Dirzo, R.; Dutoit, L. L.; Tscheulin, T.; Zouros, N.; Mescher, M. C.
10.1101/2020.08.16.227066 — ecology — Posted on 2020-08-17
2168 Single-cell analysis identifies TCF4 and ID3 as a molecular switch of mammary epithelial stem cell differentiation.
Yan, K.-K.; Nekritz, E.; Ju, B.; Dong, X.; Werner, R.; Alsina-Beauchamp, D.; Rosencrance, C.; Mukhopadhyay, P.; Pan, Q.; Gorbatenko, A.; Ding, L.; Wang, Y.; Qian, C.; Shi, H.; Shaner, B.; Natarajan, S.; Chi, H.; Easton, J.; Silva, J.; Yu, J.
10.1101/2020.08.16.249854 — developmental biology — Posted on 2020-08-17
2173 Mitochondrial determinants of response and resistance to venetoclax plus cytarabine duplet therapy in acute myeloid leukemia
Bosc, C.; Gadaud, N.; Bousard, A.; Sabatier, M.; Cognet, G.; Saland, E.; Farge, T.; Boet, E.; Gotanegre, M.; Aroua, N.; Mouchel, P.-L.; Larrue, C.; Jarrou, L.; Rambow, F.; Cabon, F.; Nicot, N.; Vergez, F.; Tamburini, J.; Fournie, J.-J.; Kaoma, T.; Marine, J.-C.; Recher, C.; Stuani, L.; Joffre, C.; Sarry, J.-E.
10.1101/2020.08.17.253856 — cancer biology — Posted on 2020-08-17
2181 Automated and unbiased classification of motor neuron phenotypes with single cell resolution in ALS tissue.
Luisier, R.; Serio, A.; Patani, R.; Newcombe, J.; Greensmith, L.; Devine, H.; Taha, D. M.; Tyzack, G. E.; Hagemann, C.
10.1101/2020.08.17.253773 — neuroscience — Posted on 2020-08-17
2182 Pancreatic α and β cells are globally phase-locked
Ren, H.; Li, Y.; Yu, Y.; Shi, B.; Peng, X.; Wu, S.; Zhu, W.; Yang, G.; Yang, X.; sneppen, k.; Chen, L.; Tang, C.
10.1101/2020.08.16.252304 — systems biology — Posted on 2020-08-17
2183 A lesson from COVID-19 on inaccessibility of web-based information for disabled populations worldwide
Dror, A. A.; Layous, E.; Mizrachi, M.; Daoud, A.; Eisenbach, N.; Morozov, N. G.; Srouji, S.; Avraham, K. B.; Sela, E.
10.1101/2020.08.16.252676 — scientific communication and education — Posted on 2020-08-17
2186 Measurement of non-purified GPCR thermostability using the homogenous ThermoBRET assay
Hoare, B. L.; Kaur, A.; Harwood, C. R.; Dijon, N. C.; Holliday, N. D.; Sykes, D. A.; Veprintsev, D.
10.1101/2020.08.05.237982 — biochemistry — Posted on 2020-08-17
2189 Old Dog, New Tricks: Influenza A Virus NS1 and In Vitro Fibrillogenesis
Shaldzhyan, A.; Zabrodskaya, Y.; Baranovskaya, I.; Sergeeva, M.; Gorshkov, A.; Savin, I.; Shishlyannikov, S.; Ramsay, E.; Protasov, A.; Kukhareva, A.; Egorov, V.
10.1101/2020.08.17.254060 — molecular biology — Posted on 2020-08-17
2191 New insights into Cryptococcus extracellular vesicles suggest a new structural model and an antifungal vaccine strategy
Rizzo, j.; Wong, S. S. W.; Gazi, A. D.; Moyrand, F.; Chaze, T.; Commere, P.-H.; Matondo, M.; Novault, S.; PEHAU-ARNAUDET, G.; Reis, F.; Vos, M.; Alves, L. R.; May, R. C.; Nimrichter, L. H.; Rodrigues, M. L.; AIMANIANDA, V.; Janbon, G.
10.1101/2020.08.17.253716 — microbiology — Posted on 2020-08-17
2193 Learning Patterns of the Ageing Brain in MRI using Deep Convolutional Networks
Dinsdale, N. K.; Bluemke, E.; Smith, S. M.; Arya, Z.; Vidaurre, D.; Jenkinson, M.; Namburete, A. I. L.
10.1101/2020.08.17.253732 — neuroscience — Posted on 2020-08-17
2195 Endosomal trafficking defects alter neural progenitor proliferation and cause microcephaly
Carpentieri, J. A.; Di Cicco, A.; Andreau, D.; Del Maestro, L.; El Marjou, F.; Coquand, l.; Brault, J.-B.; Bahi-Buisson, N.; Baffet, A.
10.1101/2020.08.17.254037 — neuroscience — Posted on 2020-08-17
2197 Integrated intra- and intercellular signaling knowledge for multicelullar omics analysis
Türei, D.; Valdeolivas, A.; Gul, L.; Palacio-Escat, N.; Ivanova, O.; Gabor, A.; Modos, D.; Korcsmaros, T.; Saez-Rodriguez, J.
10.1101/2020.08.03.221242 — systems biology — Posted on 2020-08-17
2198 Deuterated rhodamines for protein labelling in nanoscopy
Rossmann, K.; Akkaya, K. C.; Charbonnier, C.; Eichhorst, J.; Jones, B.; Lehmann, M.; Broichhagen, J.
10.1101/2020.08.17.253880 — physiology — Posted on 2020-08-17
2199 Adrenomedullin-CALCRL Axis Controls Relapse-Initiating Drug Tolerant Acute Myeloid Leukemia Cells
Larrue, C.; Guiraud, N.; Mouchel, P.-L.; Dubois, M.; Farge, T.; Gotanegre, M.; Bosc, C.; Saland, E.; Travers-Nicolau, M.-L.; Sabatier, M.; Serhan, N.; Sahal, A.; Boet, E.; Mouche, S.; Heydt, Q.; Aroua, N.; Stuani, L.; Kaoma, T.; Angenendt, L.; Mikesch, J.-H.; Schliemann, C.; Vergez, F.; Tamburini, J.; Recher, C.; Sarry, J.-E.
10.1101/2020.08.17.253542 — cancer biology — Posted on 2020-08-17
2200 In vitro culture of aberrant basal-like cells from fibrotic lung tissue
Khan, P.; Roux, J.; Blumer, S.; Fang, L.; Savic, S.; Knudsen, L.; Jonigk, D.; Kuehnel, M. P.; Gazdhar, A.; Geiser, T.; Tamm, M.; Hostettler, K. E.
10.1101/2020.08.16.247866 — cell biology — Posted on 2020-08-17
2201 Deuteration improves small-molecule fluorophores
Grimm, J. B.; Xie, L.; Casler, J. C.; Patel, R.; Tkachuk, A. N.; Choi, H.; Lippincott-Schwartz, J.; Brown, T. A.; Glick, B. S.; Liu, Z.; Lavis, L. D.
10.1101/2020.08.17.250027 — cell biology — Posted on 2020-08-17
2204 Entraining stepping movements of Parkinson's patients to alternating subthalamic nucleus deep brain stimulation
Fischer, P.; He, S.; de Roquemaurel, A.; Akram, H.; Foltynie, T.; Limousin, P.; Zrinzo, L.; Cagnan, H.; Brown, P.; Tan, H.
10.1101/2020.08.16.253062 — neuroscience — Posted on 2020-08-17
2206 Caloric Restriction Remodels Energy Metabolic Pathways of Gut Microbiota and Promotes Host Autophagy
Yang, Y.; Chen, S.; Liu, Y.; Hou, Y.; Xie, X.; Zhang, X.; Zhao, A.; Zheng, X.; Liu, J.; Chen, T.; Yuan, T.; Yu, H.; Wang, C.; Sun, Y.; Wang, J.; Wang, X.; Jia, W.
10.1101/2020.08.16.251215 — systems biology — Posted on 2020-08-17
2209 Targeting Vitamin-D receptor (VDR) by a small molecule antagonist MeTC7 inhibits PD-L1 but controls THMYCN neuroblastoma growth PD-L1 independently
Singh, R. K.; Kim, K.; Rowswell-Turner, R. B.; Hansen, J. N.; Khazan, N.; Jones, A.; Sivagnanalingam, U.; Teramoto, Y.; Goto, T.; Jian, Y.; Battaglia, N.; Conley, T.; Hovanesian, V.; Yano, N.; Pandita, R.; Arnold, L. A.; Hopson, R.; Ojha, D.; Sharon, A.; Ashton, J.; Miyamoto, H.; Schor, N. F.; Milano, M. T.; Linehan, D. T.; Gerber, S. A.; Moore, R.
10.1101/2020.08.16.252940 — cancer biology — Posted on 2020-08-17
2211 LipidFinder 2.0: advanced informatics pipeline for lipidomics discovery applications
Alvarez-Jarreta, J.; Rodrigues, P.; Fahy, E.; O'Connor, A.; Price, A.; Gaud, C.; Andrews, S.; Benton, P.; Siuzdak, G.; Hawksworth, J.; Valdivia, M.; Allen, S.; O'Donnell, V.
10.1101/2020.08.16.250878 — biochemistry — Posted on 2020-08-17
2213 Consensus-based somatic variant-calling method correlates FBXW7 mutations with poor prognosis in canine B-cell lymphoma
White, M. E.; Hayward, J. J. E.; Hertafeld, S. R.; Castelhano, M. G.; Leung, W.; Dave, S.; Bhinder, B. H.; Elemento, O. L.; Richards, K. L.; Suter, S. E.
10.1101/2020.08.16.250100 — genomics — Posted on 2020-08-17
2215 Predicting future regional tau accumulation in asymptomatic and early Alzheimer's disease
Giorgio, J.; Jagust, W. J.; Baker, S.; Landau, S. M.; Tino, P.; Kourtzi, Z.; ADNI,
10.1101/2020.08.15.252601 — neuroscience — Posted on 2020-08-17
2216 Bilateral Intracranial Beta Activity during Forced and Spontaneous Movements in a Hemi-PD Rat Model
Mottaghi, S.; Hofmann, U.; Kohl, S.; Biemann, D.; Liebana, S.; Montano, R.; Wilson, M.; Klaus, C.; Uchenik, M.; Buchholz, O.; Schmidt, R.
10.1101/2020.08.16.252957 — neuroscience — Posted on 2020-08-17
2217 Visualization of Phase-Amplitude Coupling Using Rhythmic High-Frequency Activity
Hashimoto, H.; Khoo, H. M.; Yanagisawa, T.; Tani, N.; Oshino, S.; Kishima, H.; Hirata, M.
10.1101/2020.08.12.247775 — neuroscience — Posted on 2020-08-17
2218 SIMON: open-source knowledge discovery platform
Tomic, A.; Tomic, I.; Waldron, L.; Geistlinger, L.; Kuhn, M.; Spreng, R. L.; Dahora, L. C.; Seaton, K. E.; Tomaras, G.; Hill, J.; Duggal, N. A.; Pollock, R. D.; Lazarus, N. R.; Harridge, S. D. R.; Lord, J. M.; Khatri, P.; Pollard, A. J.; Davis, M. M.
10.1101/2020.08.16.252767 — systems biology — Posted on 2020-08-17
2220 Impacts of Crenarchaeota and Halobacterota on sulfate reduction in the subtropical mangrove ecosystem as revealed by SMDB analysis
Mo, S.; Li, J.; Li, B.; Yu, R.; Nie, S.; Zhang, Z.; Kashif, M.; He, S.; Liao, J.; Jiang, Q.; Shen, P.; Yan, B.; Jiang, C.
10.1101/2020.08.16.252635 — bioinformatics — Posted on 2020-08-17
2221 Sweet chirality: the taste of L and D glucose stereoisomers
Dubovski, N.; Ben Shoshan-Galeczki, Y.; Malach, E.; Niv, M. Y.
10.1101/2020.08.16.252718 — biochemistry — Posted on 2020-08-17
2223 Transcription-coupled structural dynamics of topologically associating domains regulate replication origin efficiency
Li, Y.; Xue, B.; Zhang, L.; Su, Q. P.; Zhang, M.; Long, H.; Wang, Y.; Jin, Y.; Hou, Y.; Cao, Y.; Li, G.; sun, y.
10.1101/2020.08.16.252668 — genomics — Posted on 2020-08-17
2224 Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders
Blokland, G. A.; Grove, J.; Chen, C.-Y.; Cotsapas, C.; Tobet, S.; Handa, R.; Schizophrenia Working Group of the Psychiatric Genomics Consortium, ; St Clair, D.; Lencz, T.; Mowry, B. J.; Periyasamy, S.; Cairns, M. J.; Tooney, P. A.; Wu, J. Q.; Kelly, B.; Kirov, G.; Sullivan, P. F.; Corvin, A.; Riley, B. P.; Esko, T.; Milani, L.; Jönsson, E. G.; Palotie, A.; Ehrenreich, H.; Begemann, M.; Steixner-Kumar, A.; Sham, P. C.; Iwata, N.; Weinberger, D. R.; Gejman, P. V.; Sanders, A. R.; Buxbaum, J. D.; Rujescu, D.; Giegling, I.; Konte, B.; Hartmann, A. M.; Bramon, E.; Murray, R. M.; Pato, M. T.; Lee,
10.1101/2020.08.13.249813 — genetics — Posted on 2020-08-17
2225 How mu-Opioid Receptor Recognizes Fentanyl
Vo, Q. N.; Mahinthichaichan, P.; Shen, J.; Ellis, C. R.
10.1101/2020.08.16.253013 — biophysics — Posted on 2020-08-16
2226 Assembly of the algal CO2-fixing organelle, the pyrenoid, is guided by a Rubisco-binding motif
Meyer, M. T.; Itakura, A. K.; Patena, W.; Wang, L.; He, S.; Emrich-Mills, T.; Lau, C. S.; Yates, G.; Mackinder, L.; Jonikas, M. C.
10.1101/2020.08.16.252858 — cell biology — Posted on 2020-08-16
2227 Differential GLP-1R binding and activation by peptide and non-peptide agonists
Zhang, X.; Belousoff, M. J.; Zhao, P.; Kooistra, A. J.; Truong, T. T.; Ang, S. Y.; Underwood, C. R.; Egebjerg, T.; Senel, P.; Stewart, G. D.; Liang, Y.-L.; Glukhova, A.; Venugopal, H.; Christopoulos, A.; Furness, S. G.; Miller, L. J.; Reedtz-Runge, S.; Langmead, C. J.; Gloriam, D. E.; Danev, R.; Sexton, P. M.; Wootten, D.
10.1101/2020.08.16.252585 — pharmacology and toxicology — Posted on 2020-08-16
2232 Targeted mutagenesis of the Arabidopsis GROWTH-REGULATING FACTOR (GRF) gene family suggests competition of multiplexed sgRNAs for Cas9 apoprotein
Angulo, J.; Astin, C. P.; Bauer, O.; Blash, K. J.; Bowen, N. M.; Chukwudinma, N. J.; Dinofrio, A. S.; Faletti, D. O.; Ghulam, A. M.; Gusinde-Duffy, C. M.; Horace, K. J.; Ingram, A. M.; Isaack, K. E.; Jeong, G.; Kiser, R. I.; Kobylanski, J. S.; Long, M. R.; Manning, G. A.; Morales, J. M.; Nguyen, K. H.; Pham, R. T.; Phillips, M. H.; Reel, T. W.; Seo, J. E.; Vo, H. D.; Wukuson, A. M.; Yeary, K. A.; Zheng, G. Y.; Lukowitz, W.
10.1101/2020.08.16.253203 — plant biology — Posted on 2020-08-16
2233 Identification of microbial markers across populations in early detection of colorectal cancer
Wu, Y.; Jiao, N.; Zhu, R.; Zhang, Y.; Wu, D.; Wang, A.-j.; Fang, S.; Tao, L.; Li, Y.; Cheng, S.; He, X.; Lan, P.; Tian, C.; Liu, N.-N.; Zhu, L.
10.1101/2020.08.16.253344 — pathology — Posted on 2020-08-16
2237 Factors influencing riverine utilization patterns in two sympatric macaques
Otani, Y.; Bernard, H.; Wong, A.; Tangah, J.; Tuuga, A.; Hanya, G.; Matsuda, I.
10.1101/2020.06.11.145409 — ecology — Posted on 2020-08-16
2238 Histone demethylase complexes KDM3A and KDM3B cooperate with OCT4/SOX2 to construct pluripotency gene regulatory network
Zhu, Z.; Wu, X.; Li, Q.; Zhang, J.; Yu, S.; Shen, Q.; Zhou, Z.; Pan, Q.; Yue, W.; Qin, D.; Zhang, Y.; Zhao, W.; Zhang, R.; Peng, S.; Li, N.; Zhang, S.; Lei, A.; Miao, Y.-L.; Liu, Z.; Wang, H.; Liao, M.; Hua, J.; chen, x.
10.1101/2020.08.16.245639 — cell biology — Posted on 2020-08-16
2239 The Structural Basis of Rubisco Phase Separation in the Pyrenoid
He, S.; Chou, H.-T.; Matthies, D.; Wunder, T.; Meyer, M. T.; Atkinson, N.; Martinez-Sanchez, A.; Jeffrey, P. D.; Port, S. A.; Patena, W.; He, G.; Chen, V. K.; Hughson, F. M.; McCormick, A. J.; Mueller-Cajar, O. J.; Engel, B. D.; Yu, Z.; Jonikas, M. C.
10.1101/2020.08.16.252809 — molecular biology — Posted on 2020-08-16
2240 From the Andes to the desert: First characterization of bacterial communities in the Rimac river, the main source of water for Lima, Peru
Romero, P. E.; Calla-Quispe, E.; Castillo-Vilcahuaman, C.; Yokoo, M.; Lino Fuentes-Rivera, H.; Ramirez, J. L.; Ibanez, A. J.; Wong, P.
10.1101/2020.08.16.252965 — microbiology — Posted on 2020-08-16
2241 Hedgehog dysregulation contributes to tissue-specific inflammaging of resident macrophages
Babagana, M.; Oh, K.-S.; Chakraborty, S.; Pacholewska, ; A.; Aqdas, M.; Sung, M.-H.
10.1101/2020.08.16.253237 — immunology — Posted on 2020-08-16
2245 A Strategy to Assess the Cellular Activity of E3 Ligases against Neo-Substrates using Electrophilic Probes
Pinch, B. J.; Buckley, D. L.; Gleim, S.; Brittain, S. M.; Tandeske, L.; D'Alessandro, P. L.; Harvey, E. P.; Hauseman, Z. J.; Schirle, M.; Sprague, E. R.; Forrester, W. C.; Dovala, D.; McGregor, L. M.; Thoma, C. R.
10.1101/2020.08.13.249482 — molecular biology — Posted on 2020-08-16
2246 Methylation of RNA Cap in SARS-CoV-2 captured by serial crystallography
Wilamowski, M.; Sherrell, D.; Minasov, G.; Kim, Y.; Shuvalova, L.; Lavens, A.; Chard, R.; Maltseva, N.; Jedrzejczak, R.; Rosas-Lemus, M.; Saint, N.; Foster, I. T.; Michalska, K.; Satchell, K. J.; Joachimiak, A.
10.1101/2020.08.14.251421 — molecular biology — Posted on 2020-08-16
2247 A novel assay to isolate and quantify third-stage filarial larvae emerging from individual mosquitoes
McCrea, A. R.; Edgerton, E. B.; Oliver, G. T.; O'Neill, F. M.; Nolan, T. J.; Lok, J. B.; Povelones, M.
10.1101/2020.02.04.934653 — microbiology — Posted on 2020-08-16
2249 Human and mouse transcriptome profiling identifies cross-species homology in pulmonary and lymph node mononuclear phagocytes
Leach, S.; Gibbings, S.; Tewari, A.; Atif, S.; Vestal, B.; Danhorn, T.; Janssen, W.; Wager, T.; Jakubzick, C.
10.1101/2020.04.30.070839 — immunology — Posted on 2020-08-16
2250 Comparative morphology of the corpus callosum across the adult lifespan in chimpanzees (Pan troglodytes) and humans
Westerhausen, R.; Fjell, A. M.; Kompus, K.; Schapiro, S. J.; Sherwood, C.; Walhovd, K. B.; Hopkins, W. D.
10.1101/2020.08.15.252205 — neuroscience — Posted on 2020-08-16
2252 Inhibition underlies fast undulatory locomotion in C. elegans
Deng, L.; Denham, J.; Arya, C.; Yuval, O.; Cohen, N.; Haspel, G.
10.1101/2020.06.10.138578 — neuroscience — Posted on 2020-08-16
2254 Protein arginine methyltransferase 5 promotes metastasis via enhancing EGFR transcription and modulating AKT1 activation by methylation
Huang, L.; Zhang, X.-O.; Verdejo-Torres, O.; Wigglesworth, K.; Sun, X.; Sallis, B.; Moon, D.; Huang, T.; Rozen, E.; Zhang, L.; Wang, G.; Shohet, J. M.; Lee, M. M.; Wu, J. Q.
10.1101/2020.08.12.246660 — cancer biology — Posted on 2020-08-16
2257 MOTS-c is an Exercise-Induced Mitochondrial-Encoded Regulator of Age-Dependent Physical Decline and Muscle Homeostasis
Reynolds, J. C.; Lai, R. W.; Woodhead, J. S. T.; Joly, J. H.; Mitchell, C. J.; Cameron-Smith, D.; Lu, R.; Cohen, P.; Graham, N. A.; Benayoun, B. A.; Merry, T. L.; Lee, C.
10.1101/2019.12.22.886432 — cell biology — Posted on 2020-08-16
2262 Cell surface fluctuations regulate early embryonic lineage sorting
Yanagida, A.; Revell, C.; Stirparo, G. G.; Corujo-Simon, E.; Aspalter, I. M.; Peters, R.; Belly, H. D.; Cassani, D. A. D.; Achouri, S.; Blumenfeld, R.; Franze, K.; Paluch, E. K.; Nichols, J.; Chalut, K.
10.1101/2020.08.16.250084 — developmental biology — Posted on 2020-08-16
2263 Localized Proteotoxic Stress in Mitochondrial Intermembrane Space and Matrix Elicits Sub-compartment Specific Response Pathways Governed by Unique Modulators
Narayana Rao, K. B.; Pandey, P.; Sarkar, R.; Ghosh, A.; Mansuri, S.; Ali, M.; Majumder, P.; Ray, A.; Raychaudhuri, S.; Mapa, K.
10.1101/2020.08.16.252734 — cell biology — Posted on 2020-08-16
2265 High titers of multiple antibody isotypes against the SARS-CoV-2 spike receptor-binding domain and nucleoprotein associate with better neutralization.
Noval, M. G.; Kaczmarek, M. E.; Koide, A.; Rodriguez-Rodriguez, B. A.; Louie, P.; Tada, T.; Hattori, T.; Panchenko, T.; Romero, L. A.; Teng, K. W.; Bazley, A.; de Vries, M.; Samanovic, M. I.; Weiser, J. N.; Aifantis, I.; Cangiarella, J.; Mulligan, M. J.; Desvignes, L.; Dittmann, M.; Landau, N. R.; Aguero-Rosenfeld, M. E.; Koide, S.; Stapleford, K. A.
10.1101/2020.08.15.252353 — microbiology — Posted on 2020-08-16
2266 Susceptibility of swine cells and domestic pigs to SARS-CoV-2
Meekins, D. A.; Morozov, I.; Trujillo, J. D.; Gaudreault, N. N.; Bold, D.; Artiaga, B. L.; Indran, S. V.; Kwon, T.; Balaraman, V.; Madden, D. W.; Feldmann, H.; Henningson, J.; Ma, W.; Balasuriya, U. B. R.; Richt, J. A.
10.1101/2020.08.15.252395 — microbiology — Posted on 2020-08-16
2267 SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography
Klein, S.; Cortese, M.; Winter, S. L.; Wachsmuth-Melm, M.; Neufeldt, C. J.; Cerikan, B.; Stanifer, M. L.; Boulant, S.; Bartenschlager, R.; Chlanda, P.
10.1101/2020.06.23.167064 — microbiology — Posted on 2020-08-16
2268 A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model
Kreye, J.; Reincke, S. M.; Kornau, H.-C.; Sanchez-Sendin, E.; Corman, V. M.; Liu, H.; Yuan, M.; Wu, N. C.; Zhu, X.; Lee, C.-C. D.; Trimpert, J.; Hoeltje, M.; Dietert, K.; Stoeffler, L.; von Wardenburg, N.; van Hoof, S.; Homeyer, M. A.; Hoffmann, J.; Abdelgawad, A.; Gruber, A. D.; Bertzbach, L. D.; Vladimirova, D.; Li, L. Y.; Barthel, P. C.; Skriner, K.; Hocke, A. C.; Hippenstiel, S.; Witzenrath, M.; Suttorp, N.; Kurth, F.; Franke, C.; Endres, M.; Schmitz, D.; Jeworowski, L. M.; Richter, A.; Schmidt, M. L.; Schwarz, T.; Mueller, M. A.; Drosten, C.; Wendisch, D.; Sander, L. E.; Osterrieder, N.;
10.1101/2020.08.15.252320 — immunology — Posted on 2020-08-16
2271 Multiple regions of primate orofacial sensorimotor cortex encode bite force and gape
Arce-McShane, F.; Sessle, B. J.; Ram, Y.; Balcer, C. A.; Ross, C.; Hatsopoulos, N. G.
10.1101/2020.08.16.252817 — neuroscience — Posted on 2020-08-16
2272 High-resolution Introgressive Region Map Reveals Spatiotemporal Genome Evolution in Asian Rice Domestication
Ohyanagi, H.; Goto, K.; Negrao, S.; Wing, R.; Tester, M.; McNally, K.; Bajic, V.; Mineta, K.; Gojobori, T.
10.1101/829168 — plant biology — Posted on 2020-08-16
2273 Design of a highly thermotolerant, immunogenic SARS-CoV-2 spike fragment
Malladi, S. K.; Singh, R.; Pandey, S.; Gayathri, S.; Kanjo, K.; Ahmed, S.; Khan, M. S.; Kalita, P.; Girish, N.; Upadhyaya, A.; Reddy, P.; Pramanick, I.; Bhasin, M.; Mani, S.; Bhattacharyya, S.; Joseph, J.; Thankamani, K.; Raj, V. S.; Dutta, S.; Singh, R.; Nadig, G.; Varadarajan, R.
10.1101/2020.08.15.252437 — biophysics — Posted on 2020-08-16
2278 De Novo Designed Peptide and Protein Hairpins that Self-assemble into Sheets and Nanoparticles.
Galloway, J. M.; Bray, H. E. V.; Shoemark, D. K.; Hodgson, L. R.; Coombs, J.; Mantell, J. M.; Rose, R. S.; Ross, J. F.; Morris, C.; Harniman, R. L.; Wood, C. W.; Arthur, C.; Verkade, P.; Woolfson, D. N.
10.1101/2020.08.14.251462 — synthetic biology — Posted on 2020-08-16
2279 Airborne point counts: a method for estimating songbird abundance with drones
Somers, M. D.; Glass, D. B.; Immordino, M. A.; Ozoh, P. S.; Sherman, L. B.; Wilson, A. M.
10.1101/2020.08.15.252429 — ecology — Posted on 2020-08-16
2280 Identification of zinc-dependent mechanisms used by Group B Streptococcus to overcome calprotectin-mediated stress
Burcham, L. R.; Le Breton, Y.; Radin, J. N.; Spencer, B.; Deng, L.; Hiron, A.; Ransom, M. R.; Mendonca, J. d. C.; Belew, A. T.; El-Sayed, N. M.; McIver, K. S.; Kehl-Fie, T. E.; Doran, K.
10.1101/2020.08.14.252064 — microbiology — Posted on 2020-08-16
2281 Bird populations most exposed to climate change are less responsive to climatic variation
Bailey, L. D.; van de Pol, M.; Adriaensen, F.; Barba, E.; Bellamy, P. E.; Bouvier, J.-C.; Burgess, M. D.; Charmantier, A.; Cusimano, C.; Doligez, B.; Drobniak, S. M.; Dubiec, A.; Eens, M.; Eeva, T.; Ferns, P. N.; Goodenough, A. E.; Hartley, I. R.; Hinsley, S. A.; Ivankina, E.; Juskaitis, R.; Kempenaers, B.; Kerimov, A. B.; Lauriere, A.; Lavigne, C.; Leivits, A.; Mainwaring, M. C.; Matthysen, E.; Nilsson, J.-A.; Orell, M.; Rytkonen, S.; Senar, J. C.; Sheldon, B. C.; Sorace, A.; Stenning, M. J.; Torok, J.; Vatka, E.; Vriend, S. J. G.; Visser, M. E.
10.1101/2020.08.16.252379 — ecology — Posted on 2020-08-16
2282 An early Sox2-dependent gene expression program required for hippocampal dentate gyrus development
Mercurio, S.; Alberti, C.; Serra, L.; Meneghini, S.; Bertolini, J.; Berico, P.; Becchetti, A.; Nicolis, S. K.
10.1101/2020.08.16.252684 — developmental biology — Posted on 2020-08-16
2283 A refined method to monitor arousal from hibernation in the European hamster
Markussen, F. A. S.; Melum, V. J.; Bothorel, B.; Hazlerigg, D. G.; Simonneaux, V.; Wood, S. H.
10.1101/2020.04.20.009712 — physiology — Posted on 2020-08-16
2284 Human Embryonic Expression Identifies Novel Essential Gene Candidates
Penon Portmann, M.; Chang, J.; Blair, D. R.; Rodriguez-Alonso, B.; Cakmak, H.; Rajkovic, A.; Shieh, J. T.
10.1101/2020.08.15.252338 — genetics — Posted on 2020-08-15
2286 Human ORC/MCM density is low in active genes and correlates with replication time but does not solely define replication initiation zones
Kirstein, N.; Buschle, A.; Wu, X.; Krebs, S.; Blum, H.; Hammerschmidt, W.; Lacroix, L.; Hyrien, O.; Audit, B.; Schepers, A.
10.1101/2020.08.15.252221 — cell biology — Posted on 2020-08-15
2287 Implicit anticipation of probabilistic regularities: Larger CNV emerges for unpredictable events
Kobor, A.; Kardos, Z.; Horvath, K.; Janacsek, K.; Takacs, A.; Csepe, V.; Nemeth, D.
10.1101/2020.08.14.251686 — neuroscience — Posted on 2020-08-15
2288 Hearing loss in Alzheimer Disease is associated with altered serum lipidomic biomarker profiles
Llano, D. A.; Issa, L.; Devanarayan, P.; Devanarayan, V. A.; Alzheimer Disease Neuroimaging Initiative,
10.1101/2020.08.15.252452 — neuroscience — Posted on 2020-08-15
2290 Semecarpus anacardium Linn. leaf extract exhibits activities against breast cancer and prolongs the survival of tumor bearing mice
Singh, R. K.; Ranjan, A.; Tripathi, R.; Verma, S. S.; Sharma, V.; Singh, M.; Gupta, S. C.; Singh, A. K.; Srivastava, A. K.
10.1101/2020.01.08.898940 — pharmacology and toxicology — Posted on 2020-08-15
2291 Electronic cigarettes induce mitochondrial DNA damage and trigger toll-like receptor 9-mediated atherosclerosis
Li, J.; Huynh, D. L.; Tang, M.-S.; Simborio, H.; Huang, J.; Kosmider, B.; Steinberg, M. B.; Le, L. T. T.; Pham, K.; Liu, C.; Wang, H.
10.1101/2020.08.15.252494 — pharmacology and toxicology — Posted on 2020-08-15
2294 Fibroblasts close a void in free space by a purse-string mechanism
Da Costa, A. D. S.; Subiah, R.; Oh, S. J.; Jeong, H. T.; Na, J.-I.; Park, K.; Shin, J. H.; Choi, I.-S.
10.1101/2020.08.15.250811 — biophysics — Posted on 2020-08-15
2296 TISCH: a comprehensive web resource enabling interactive single-cell transcriptome visualization of tumor microenvironment
Sun, D.; Wang, J.; Han, Y.; Dong, X.; Zheng, R.; Ge, J.; Shi, X.; Wang, B.; Li, Z.; Ren, P.; Sun, L.; Yan, Y.; Zhang, P.; Zhang, F.; Li, T.; Wang, C.
10.1101/2020.08.15.251959 — bioinformatics — Posted on 2020-08-15
2299 Rapid cost-effective viral genome sequencing by V-seq
Guo, L.; Boocock, J.; Tome, J.; Chandrasekaran, S.; Hilt, E. E.; Zhang, Y.; Sathe, L.; Li, X.; Luo, C.; Kosuri, S.; Shendure, J.; Arboleda, V. A.; Flint, J.; Eskin, E.; Garner, O. B.; Yang, S.; Bloom, J. S.; Kruglyak, L.; Yin, Y.
10.1101/2020.08.15.252510 — genomics — Posted on 2020-08-15
2301 Structural adaptation of oxygen tolerance in 4-hydroxybutyrl-CoA dehydratase, a key enzyme of archaeal carbon fixation
DeMirci, H.; Tolar, B.; Doukov, T.; Petriceks, A.; Pal, A.; Yoshikuni, Y.; Gomez, A.; Saez, D. A.; Vohringer-Martinez, E.; Schwander, T.; Erb, T. J.; Francis, C. A.; Wakatsuki, S.
10.1101/2020.02.05.935528 — evolutionary biology — Posted on 2020-08-15
2303 Evidence-based gene expression modulation correlates with transposable element knock-down
Hernandes-Lopes, J.; Quintanilha, D. M.; de Jesus, E. M.; Lopes, F. M.; Parmigiani, R. B.; Karolski, B.; Dias, H. M.; Jacobs, T. B.; Camargo, A. A.; Kitajima, J. P.; Van Sluys, M.-A.
10.1101/2020.08.15.252312 — molecular biology — Posted on 2020-08-15
2304 BamA and BamD are essential for the secretion of trimeric autotransporter adhesins
Rooke, J.; Icke, C.; Wells, T. J.; Rossiter, A. E.; Browning, D. F.; Morris, F. C.; Leo, J.; Schuetz, M. S.; Autenrieth, I. B.; Cunningham, A. F.; Linke, D.; Henderson, I. R.
10.1101/2020.08.14.252015 — microbiology — Posted on 2020-08-15
2305 SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2
Heaton, B. E.; Trimarco, J. D.; Hamele, C. E.; Harding, A. T.; Tata, A.; Zhu, X.; Tata, P. R.; Smith, C. M.; Heaton, N. S.
10.1101/2020.08.14.251207 — microbiology — Posted on 2020-08-15
2306 Comparative morphology of the corpus callosum across the adult lifespan in chimpanzees (Pan troglodytes) and humans
Westerhausen, R.; Fjell, A. M.; Kompus, K.; Steven, S. J.; Sherwood, C.; Walhovd, K. B.; Hopkins, W. D.
10.1101/2020.08.15.252205 — neuroscience — Posted on 2020-08-15
2308 Sotagliflozin, a dual SGLT1/2 inhibitor, improves cardiac outcomes in a mouse model of early heart failure without diabetes
Young, S. L.; Ryan, L.; Mullins, T. P.; Flint, M.; Steane, S. E.; Walton, S. L.; Bielefeldt-Ohmann, H.; Carter, D. A.; Reichelt, M. E.; Gallo, L. A.
10.1101/2020.08.15.252593 — pharmacology and toxicology — Posted on 2020-08-15
2310 FAIRSCAPE: A Framework for FAIR and Reproducible Biomedical Analytics
Levinson, M. A.; Niestroy, J.; Al Manir, S.; Fairchild, K. D.; Lake, D. E.; Moorman, J. R.; Clark, T.
10.1101/2020.08.10.244947 — bioinformatics — Posted on 2020-08-15
2314 Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2
Kawale, A. A.; Taliaferro, J. M.; Kang, H.-S.; Hartmueller, C.; Geerlof, A.; Stehle, R.; Burge, C.; Rio, D. C.; Sattler, M.
10.1101/2020.08.15.252130 — biochemistry — Posted on 2020-08-15
2322 Singleton phage BlueFeather reveals novel relationships in the Arthrobacter phage population
Demo, S.; Kapinos, A.; Bernardino, A.; Guardino, K.; Hobbs, B.; Hoh, K.; Lee, E.; Vuong, I.; Reddi, K.; Freise, A. C.; Moberg Parker, J.
10.1101/2020.08.15.252577 — microbiology — Posted on 2020-08-15
2323 Identification and characterization of CD4+ T cell epitopes after Shingrix vaccination.
Voic, H.; de Vries, R. D.; Sidney, J.; Rubiro, P.; Moore, E.; Phillips, E. J.; Mallal, S.; Schwan, B.; Weiskopf, D.; Grifoni, A.; Sette, A.
10.1101/2020.07.29.227082 — immunology — Posted on 2020-08-15
2326 Utilizing Computational Machine Learning Tools to Understand Immunogenic Breadth in the Context of a CD8 T-Cell Mediated HIV Response
McGowan, E.; Rosenthal, R.; Fiore-Gartland, A.; Macharia, G.; Balinda, S.; Kapaata, A.; Muok, E.; Umviligihozo, G.; Dalel, J.; Streatfield, C.; Coutinho, H.; Monaco, D.; Morrison, D.; Yue, L.; Hunter, E.; Nielsen, M.; Gilmour, J.; Hare, J.
10.1101/2020.08.15.250589 — immunology — Posted on 2020-08-15
2327 Contribution of resident and circulating precursors to tumor-infiltrating CD8+ T cell populations in non-small cell lung cancer patients
Metoikidou, C.; Gueguen, P.; Dupic, T.; Lawand, M.; Goudot, C.; Baulande, S.; Lameiras, S.; Lantz, O.; Girard, N.; Seguin-Givelet, A.; Lefevre, M.; Mora, T.; Walczak, A.; Waterfall, J. J.; Amigorena, S.
10.1101/2020.08.14.249789 — immunology — Posted on 2020-08-15
2329 Systems Biology behind immunoprotection of both Sheep and Goats after Sungri/96 PPRV vaccination
Wani, S. A.; Praharaj, M. R.; Sahu, A. R.; Nabi Khan, R. I.; Rajak, K. K.; Muthuchelvan, D.; Sahoo, A.; Mishra, B.; Singh, R. K.; Mishra, B. P.; Gandham, R. K.
10.1101/2020.08.14.252056 — systems biology — Posted on 2020-08-15
2333 Antioxidant nanozyme counteracts HIV-1 by modulating intracellular redox potential
Singh, S.; Ghosh, S.; Pal, V. K.; Munshi, M.; Rajmani, R. S.; Mugesh, G.; Singh, A.
10.1101/2020.08.15.252098 — bioengineering — Posted on 2020-08-15
2334 A maternal effect regulates global DNA methylation patterns
Loos, R.; Carola, V.; Audero, E.; Brini, E.; Lo Iacono, L.; Moles, A.; Bertone, P.; Gross, C. T.
10.1101/2020.08.15.252239 — genomics — Posted on 2020-08-15
2335 Nitric oxide prevents aortic valve calcification by S-nitrosylation of USP9X to activate NOTCH signaling
Majumdar, U.; Manivannan, S.; Basu, M.; Ueyama, Y.; Blaser, M. C.; Cameron, E.; McDermott, M. R.; Lincoln, J.; Cole, S. E.; Wood, S.; Aikawa, E.; Lilly, B.; Garg, V.
10.1101/2020.08.15.252171 — cell biology — Posted on 2020-08-15
2336 In plain sight: the role of alpha-1-antitrypsin in COVID-19 pathogenesis and therapeutics.
Oguntuyo, K. Y.; Stevens, C. S.; Siddiquey, M. N.; Schilke, R. M.; Woolard, M. D.; Zhang, H.; Acklin, J. A.; Ikegame, S.; Hung, C.-t.; Lim, J. K.; Cross, R. W.; Geisbert, T. W.; Ivanov, S. S.; Kamil, J. P.; Lee, B.
10.1101/2020.08.14.248880 — microbiology — Posted on 2020-08-15
2338 Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer
Siddiqui, M. A.; Gollavilli, P. N.; Ramesh, V.; Parma, B.; Schwab, A.; Vazakidou, M. E.; Natesan, R.; Saatci, O.; Rapa, I.; Bironzo, P.; Schuhwerk, H.; Asangani, I. A.; Sahin, O.; Volante, M.; Ceppi, P.
10.1101/2020.08.13.249581 — cancer biology — Posted on 2020-08-15
2339 Inhibition of Severe Acute Respiratory Syndrome Coronavirus 2 main protease by tafenoquine in vitro
Chen, Y.; Yang, W.-H.; Huang, L.-M.; Wang, Y.-C.; Yang, C.-S.; Liu, Y.-L.; Hou, M.-H.; Tsai, C.-L.; Chou, Y.-Z.; Huang, B.-Y.; Hung, C.-F.; Hung, Y.-L.; Chen, J.-S.; Chiang, Y.-P.; Cho, D.-Y.; Jeng, L.-B.; Tsai, C.-H.; Hung, M.-C.
10.1101/2020.08.14.250258 — biochemistry — Posted on 2020-08-15
2340 At least seven distinct rotavirus genotype constellations in bats with evidence of reassortment and zoonotic transmissions
Simsek, C.; Corman, V. M.; Everling, H. U.; Lukashev, A. N.; Rasche, A.; Maganga, G. D.; Binger, T.; Jansen, D.; Beller, L.; Deboutte, W.; Gloza-Rausch, F.; Seebens-Hoyer, A.; Yordanov, S.; Sylverken, A.; Oppong, S. K.; Abu-Sarkodie, Y.; Vallo, P.; Leroy, E.; Bourgarel, M.; Yinda, K. C.; Van Ranst, M.; Drosten, C.; Drexler, J. F.; Matthijnssens, J.
10.1101/2020.08.13.250464 — microbiology — Posted on 2020-08-15
2342 Synaptic anchoring of the endoplasmic reticulum depends on myosin V and caldendrin activity
Konietzny, A.; Grendel, J.; Hertrich, N.; Dekkers, D. H. W.; Demmers, J. A.; Mikhaylova, M.
10.1101/2020.08.14.250746 — neuroscience — Posted on 2020-08-15
2344 Extracellular matrix supports excitation-inhibition balance in neuronal networks by stabilizing inhibitory synapses
Dzyubenko, E.; Fleischer, M.; Manrique-Castano, D.; Borbor, M.; Kleinschnitz, C.; Faissner, A.; Hermann, D. M.
10.1101/2020.07.13.200113 — neuroscience — Posted on 2020-08-15
2345 Thiamethoxam exposure deregulates short ORF gene expression in the honey bee and compromises immune response to bacteria
Decio, P.; Ustaoglu, P.; Derecka, K.; Hardy, I.; Roat, T.; Malaspina, O.; Mongan, N.; Stoger, R.; Soller, M.
10.1101/853291 — pharmacology and toxicology — Posted on 2020-08-15
2349 Nitric oxide-inducible Fe-S cluster biogenesis enables Mycobacterium tuberculosis to persist in mice
Anand, K.; Tripathi, A.; Shukla, K.; Malhotra, N.; Jamithireddy, A.; Jha, R. K.; Chaudhury, S. N.; Rajmani, R. S.; Ramesh, A.; Nagaraja, V.; Gopal, B.; Nagaraju, G.; Seshasayee, A. S. N.; Singh, A.
10.1101/2020.08.10.245365 — microbiology — Posted on 2020-08-15
2350 Learned adaptive multiphoton illumination microscopy
Pinkard, H.; Baghdassarian, H.; Mujal, A.; Roberts, E.; Hu, K. H.; Friedman, D. H.; Malenica, I.; Shagam, T.; Fries, A.; Corbin, K.; Krummel, M. F.; Waller, L.
10.1101/2020.08.14.251314 — immunology — Posted on 2020-08-15
2353 Whole-brain mapping of monosynaptic inputs to midbrain cholinergic neurons
Huerta-Ocampo, I.; Dautan, D.; Gut, N. K.; Khan, B.; Mena-Segovia, J.
10.1101/2020.08.14.251546 — neuroscience — Posted on 2020-08-15
2354 Virtual screening of MAP-Tau protein inhibitors from Semecarpus anacardium Linn. leaf extract for cancer prevention
Singh, R. K.; Singh, A. K.; Ranjan, A.; Tripathi, R.; Srivastava, A. K.; Singh, M.; Kumar, A.; Dwivedi, K. N.
10.1101/2020.01.08.899708 — bioinformatics — Posted on 2020-08-14
2358 Testing the predictability of morphological evolution in contrasting thermal environments
Pilakouta, N.; Humble, J. L.; Hill, I. D. C.; Arthur, J.; Costa, A.; Smith, B.; Kristjansson, B. K.; Skulason, S.; Killen, S. S.; Lindstrom, J.; Metcalfe, N. B.; Parsons, K. J.
10.1101/609933 — evolutionary biology — Posted on 2020-08-14
2360 Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis
Imamura, H.; Sakamoto, S.; Yoshida, T.; Matsui, Y.; Penuela, S.; Laird, D.; Mizukami, S.; Kikuchi, K.; Kakizuka, A.
10.1101/2020.08.14.247296 — cell biology — Posted on 2020-08-14
2362 Logical modeling of dendritic cells in vitro differentiation from human monocytes unravels novel transcriptional regulatory interactions
Nunez-Reza, K. J.; Naldi, A.; Sanchez-Jimenez, A.; Leon-Apodaca, A. V.; Santana, M. A.; Thomas-Chollier, M.; Thieffry, D.; Medina-Rivera, A.
10.1101/2020.08.14.251710 — immunology — Posted on 2020-08-14
2363 Structural and biochemical mechanisms of NLRP1 inhibition by DPP9
Huang, M.; Zhang, X.; Ann, T. G.; Gong, Q.; Wang, J.; Han, Z.; Wu, B.; Zhong, F. L.; Chai, J.
10.1101/2020.08.13.250241 — immunology — Posted on 2020-08-15
2365 Large-scale Phenomic and Genomic Analysis of Brain Asymmetrical Skew
Kong, X.; Postema, M. C.; Carrion Castillo, A.; Pepe, A.; Crivello, F.; Joliot, M.; Mazoyer, B.; Fisher, S. E.; Francks, C.
10.1101/756395 — neuroscience — Posted on 2020-08-14
2366 Cortical thickness estimation in individuals with cerebral small vessel disease, focal atrophy, and chronic stroke lesions.
Ozzoude, M.; Ramirez, J.; Raamana, P. R.; Holmes, M. F.; Walker, K.; Scott, C. J. M.; Goubran, M.; Kwan, D.; Tartaglia, M. C.; Beaton, D.; Strother, S. C.; Symons, S.; Bartha, R.; Swartz, R. H.; Black, S. E.; on behalf of the ONDRI Investigators,
10.1101/2020.08.04.236760 — neuroscience — Posted on 2020-08-14
2368 Organophosphorus diisopropylfluorophosphate (DFP) intoxication in zebrafish larvae causes behavioral defects, neuronal hyperexcitation and neuronal death
Brenet, A.; Somkhit, J.; Hassan-Abdi, R.; Yanicostas, C.; Igert, A.; Saurat, D.; Taudon, N.; Dal-Bo, G.; Nachon, F.; Dupuis, N.; Soussi-Yanicostas, N.
10.1101/2019.12.15.876649 — neuroscience — Posted on 2020-08-15
2369 Elucidation and refinement of synthetic receptor mechanisms
Edelstein, H. I.; Donahue, P. S.; Muldoon, J. J.; Kang, A. K.; Dolberg, T. B.; Battaglia, L. M.; Allchin, E. R.; Hong, M.; Leonard, J. N.
10.1101/2020.04.16.045039 — synthetic biology — Posted on 2020-08-14
2371 Mechanical Feedback and Robustness of Apical Constrictions in Drosophila Embryo Ventral Furrow Formation
Holcomb, M. C.; Gao, G.-J. J.; Servati, M.; Schneider, D.; McNeely, P. K.; Thomas, J. H.; Blawzdziewicz, J.
10.1101/743609 — biophysics — Posted on 2020-08-14
2376 Transcriptomic and epigenomic dynamics of honey bees in response to lethal IAPV viral infection
Li-Byarlay, H.; Boncristiani, H.; Howell, G.; Herman, J.; Clark, L.; Strand, M.; Tarpy, D.; Rueppell, O.
10.1101/2020.08.14.251769 — genomics — Posted on 2020-08-14
2379 The essential role of Dnmt1 in gametogenesis in the large milkweed bug Oncopeltus fasciatus
Washington, J. T.; Cavender, K. R.; Amukamara, A. U.; McKinney, E. C.; Schmitz, R. J.; Moore, P. J.
10.1101/2020.07.23.218180 — evolutionary biology — Posted on 2020-08-14
2380 Spotting genome-wide pigmentation variation in a brown trout admixture context
VALETTE, T.; LEITWEIN, M.; LASCAUX, J.-M.; DESMARAIS, E.; BERREBI, P.; GUINAND, B.
10.1101/2020.07.23.217109 — evolutionary biology — Posted on 2020-08-14
2383 Abortive Intussusceptive Angiogenesis Causes Multi-Cavernous Vascular Malformations
Li, W.; Tran, V.; Shaked, I.; Xue, B.; Moore, T.; Lightle, R.; Kleinfeld, D.; Awad, I. A.; Ginsberg, M.
10.1101/2020.08.14.251744 — developmental biology — Posted on 2020-08-14
2386 ipaA triggers vinculin oligomerization to strengthen cell adhesion during Shigella invasion
Valencia-Gallardo, C.; Aguilar Salvador, D. I.; Khazad, H.; Bou-Nader, C.; Malosse, C.; Borges-Lima, D.; Bello, C.; Cocom-Chan, B.; Quenech'Du, N.; Mazhar, B.; Javelaud, D.; Fattaccioli, J.; Mauviel, A.; Fontecave, M.; Asnacios, A.; Chamot-Rooke, J.; Malmstrom, L.; Tran Van Nhieu, G.
10.1101/773283 — cell biology — Posted on 2020-08-14
2388 Early enforcement of cell identity by a functional component of the terminally differentiated state
Bahrami-Nejad, Z.; Chen, T.; Tholen, S.; Zhang, Z.-b.; Rabiee, A.; Zhao, M. L.; Teruel, M.
10.1101/2020.01.03.894493 — cell biology — Posted on 2020-08-14
2390 Comparison of methods for milk pre-processing, exosome isolation, and RNA extraction in bovine and human milk
Wijenayake, S.; Eisha, S.; Tawhidi, Z.; Pitino, M. A.; Steele, M. A.; Fleming, A. S.; McGowan, P.
10.1101/2020.08.14.251629 — molecular biology — Posted on 2020-08-14
2391 Gut microbiome composition predicts summer core range size in a generalist and specialist ungulate
Wolf, J. F.; Kriss, K. D.; MacAulay, K. M.; Munro, K.; Patterson, B. R.; Shafer, A. B. A.
10.1101/2020.08.04.236638 — molecular biology — Posted on 2020-08-14
2392 Microbiota-directed fibre activates both targeted and secondary metabolic shifts in the distal gut.
Michalak, L.; Gaby, J. C.; Lagos, L.; La Rosa, S. L.; Hvidsten, T. R.; Tetard-Jones, C.; Willats, W. G. T.; Terrapon, N.; Lombard, V.; Henrissat, B.; Droge, J.; Arntzen, M.; Hagen, L. H.; Overland, M.; Pope, P. B.; Westereng, B.
10.1101/799023 — microbiology — Posted on 2020-08-14
2393 Time-course of systems consolidation and fear memory generalization in adolescent rats of different sex
Crestani, A. P.; Lotz, F. N.; Casagrande, M. A.; Popik, B.; Guerra, K. T. K.; de Oliveira Alvares, L.; Quillfeldt, J. A.
10.1101/2020.08.14.250860 — neuroscience — Posted on 2020-08-14
2394 Evoked pain intensity representation is distributed across brain systems: A multistudy mega-analysis
Petre, B.; Kragel, P. A.; Atlas, L. Y.; Geuter, S.; Jepma, M.; Koban, L.; Krishnan, A.; Lopez-Sola, M.; Roy, M.; Woo, C.-W.; Wager, T. D.
10.1101/2020.07.04.182873 — neuroscience — Posted on 2020-08-14
2395 A human-specific modifier of cortical circuit connectivity and function improves behavioral performance
Schmidt, E. R. E.; Zhao, H. T.; Park, J. M.; Dahan, J. B.; Rodgers, C. C.; Hillman, E. M. C.; Bruno, R. M.; Polleux, F.
10.1101/852970 — neuroscience — Posted on 2020-08-14
2398 Greater male than female variability in regional brain structure across the lifespan
Wierenga, L. M.; Doucet, G. E.; Dima, D.; Agartz, I.; Aghajani, M.; Akudjedu, T. N.; Albajes-Eizagirre, A.; Alnaes, D.; Alpert, K. I.; Andreassen, O. A.; Anticevic, A.; Asherson, P.; Banaschewski, T.; Bargallo, N.; Baumeister, S.; Baur-Streubel, R.; Bertolino, A.; Bonvino, A.; Boomsma, D. I.; Borgwardt, S.; Bourque, J.; den Braber, A.; Brandeis, D.; Breier, A.; Brodaty, H.; Brouwer, R. M.; Buitelaar, J. K.; Busatto, G. F.; Calhoun, V. D.; Canales-Rodriguez, E. J.; Cannon, D.; Caseras, X.; Chaim-Avancini, T.; Castellanos, F. X.; Chaim-Avancini, T. M.; Ching, C. R.; Clark, V. P.; Conrod, P. J.;
10.1101/2020.02.17.952010 — neuroscience — Posted on 2020-08-14
2400 Embodied Cognition and Decision-Making in the Primate Superior Colliculus
Jun, E. J.; Bautista, A.; Nunez, M. D.; Tak, T.; Alvarez, E.; Basso, M. A.
10.1101/2020.08.14.251777 — neuroscience — Posted on 2020-08-14
2401 Implicit anticipation of probabilistic regularities: Larger CNV emerges for unpredictable events
Andrea, K.; Kardos, Z.; Horvath, K.; Janacsek, K.; Takacs, A.; Csepe, V.; Nemeth, D.
10.1101/2020.08.14.251686 — neuroscience — Posted on 2020-08-14
2404 PRG2 and AQPEP are misexpressed in fetal membranes in placenta previa and percreta
Zhang, E. T.; Hannibal, R. L.; Badillo Rivera, K. M.; Song, J. H. T.; McGowan, K.; Zhu, X.; Meinhardt, G.; Knöfler, M.; Pollheimer, J.; Urban, A. E.; Folkins, A. K.; Lyell, D. J.; Baker, J. C.
10.1101/2020.08.14.248807 — pathology — Posted on 2020-08-14
2407 CopR, a global regulator of transcription to maintain copper homeostasis in Pyrococcus furiosus
Gruenberger, F.; Reichelt, R.; Waege, I.; Ned, V.; Bronner, K.; Kaljanac, M.; Weber, N.; El-Ahmad, Z.; Knauss, L.; Madej, M. G.; Ziegler, C.; Grohmann, D.; Hausner, W.
10.1101/2020.08.14.251413 — microbiology — Posted on 2020-08-14
2409 Ex vivo detection of SARS-CoV-2-specific CD8+ T cells: rapid induction, prolonged contraction, and formation of functional memory
Schulien, I.; Kemming, J.; Oberhardt, V.; Wild, K.; Seidel, L. M.; Killmer, S.; Sagar, ; Daul, F.; Salvat Lago, M.; Decker, A.; Luxenburger, H.; Binder, B.; Bettinger, D.; Sogukpinar, O.; Rieg, S.; Panning, M.; Huzly, D.; Schwemmle, M.; Kochs, G.; Waller, C. F.; Nieters, A.; Duerschmied, D.; Emmerich, F.; Mei, H.; Schulz, A.; Llewellyn-Lacey, S.; Price, D. A.; Boettler, T.; Bengsch, B.; Thimme, R.; Hofmann, M.; Neumann-Haefelin, C.
10.1101/2020.08.13.249433 — immunology — Posted on 2020-08-14
2410 Tissue-resident memory CD8 T-cell responses elicited by a single injection of a multi-target COVID-19 vaccine
Gauttier, V.; Morello, A.; Girault, I.; Mary, C.; Belarif, L.; Desselle, A.; Wilhelm, E.; Bourquard, T.; Pengam, S.; Teppaz, G.; Thepenier, V.; Biteau, K.; De Barbeyrac, E.; Kiepferle, D.; Vasseur, B.; Le Flem, F.-X.; Debieuvre, D.; Costantini, D.; Poirier, N.
10.1101/2020.08.14.240093 — immunology — Posted on 2020-08-14
2412 The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma
Polaski, J. T.; Udy, D. B.; Escobar-Hoyos, L. F.; Askan, G.; Leach, S. D.; Ventura, A.; Kannan, R.; Bradley, R. K.
10.1101/2020.08.14.248864 — cancer biology — Posted on 2020-08-14
2414 MRLocus: identifying causal genes mediating a trait through Bayesian estimation of allelic heterogeneity
Zhu, A.; Matoba, N.; Wilson, E.; Tapia, A. L.; Li, Y.; Ibrahim, J. G.; Stein, J. L.; Love, M. I.
10.1101/2020.08.14.250720 — bioinformatics — Posted on 2020-08-14
2419 Involvement of uterine natural killer cells in the natural selection of human embryos at implantation.
Kong, C.-S.; Almansa Ordonez, A.; Turner, S.; Tremaine, T.; Muter, J.; Lucas, E.; Salisbury, E.; Vassena, R.; Fouladi-Nashta, A.; Tiscornia, G.; Hartshorne, G.; Brosens, J.; Brighton, P.
10.1101/2020.08.14.251033 — cell biology — Posted on 2020-08-14
2420 Capturing in situ Virus-Host Range and Interaction Dynamics through Gene Fusion with epicPCR
Sakowski, E. G.; Arora-Williams, K.; Tian, F.; Zayed, A.; Zablocki, O.; Sullivan, M. B.; Preheim, S. P.
10.1101/2020.08.14.250803 — microbiology — Posted on 2020-08-14
2423 SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2
Heaton, B. E.; Trimarco, J. D.; Hamele, C. E.; Harding, A. T.; Tata, A.; Zhu, X.; Tata, P. R.; Smith, C. M.; Heaton, N. S.
10.1101/2020.08.14.251207 — microbiology — Posted on 2020-08-14
2424 ERAP2 facilitates a subpeptidome of Birdshot Uveitis-associated HLA-A29
Venema, W.; Hiddingh, S.; de Boer, J. H.; Claas, F.; Mulder, A.; Hollander, A. D.; Stratikos, E.; Sarkizova, S.; Janssen, G.; Veelen, P. v.; Kuiper, J. J.
10.1101/2020.08.14.250654 — immunology — Posted on 2020-08-14
2426 The developing T-cell compartment of the neonatal lung orchestrates an atypical response to respiratory syncytial virus
Demoulins, T.; Bruegger, M.; Zumhehr, B.; Oliveira Esteves, B.; Mehinagic, K.; Fahmi, A.; Borcard, L.; Posthaus, H.; Benarafa, C.; Ruggli, N.; Alves, M. P.
10.1101/2020.08.14.250829 — immunology — Posted on 2020-08-14
2427 Multisensory processes can compensate for attention deficits in schizophrenia
Moran, J. K.; Keil, J.; Masurovsky, A.; Gutwinski, S.; Montag, C.; Senkowski, D.
10.1101/2020.08.14.251405 — neuroscience — Posted on 2020-08-14
2431 Influenza A virus diffusion through mucus gel networks
Kaler, L.; Iverson, E.; Bader, S.; Song, D.; Scull, M. A.; Duncan, G.
10.1101/2020.08.14.251132 — biophysics — Posted on 2020-08-14
2434 Investigation of Capsule-Inspired Neural Network Approaches for DNA Methylation
Levy, J.; Chen, Y.; Azizgolshani, N.; Petersen, C. L.; Titus, A. J.; Moen, E. L.; Vaickus, L. J.; Salas, L. A.; Christensen, B.
10.1101/2020.08.14.251306 — bioinformatics — Posted on 2020-08-14
2438 Chloroquine and hydroxychloroquine as ACE2 blockers to inhibit viropexis of 2019-nCoV Spike pseudotyped virus
Wang, N.; Han, S.; Liu, R.; Meng, L.; He, H.; Zhang, Y.; Wang, C.; Lv, Y.; Wang, J.; Li, X.; Ding, Y.; Fu, J.; Hou, Y.; Lu, W.; Ma, W.; Zhan, Y.; Dai, B.; Zhang, J.; Pan, X.; Hu, S.; Gao, J.; Jia, Q.; Zhang, L.; Ge, S.; Wang, S.; Liang, P.; Hu, T.; Lu, J.; Wang, X.; Zhou, H.; Ta, W.; Wang, Y.; Lu, S.; He, L.
10.1101/2020.06.22.164665 — biochemistry — Posted on 2020-08-14
2440 Differential methylation as a mediator of COVID-19 susceptibility
Steyaert, S.; Trooskens, G.; Delanghe, J. R.; Van Criekinge, W.
10.1101/2020.08.14.251538 — genomics — Posted on 2020-08-14
2441 Genotypic diversity and dynamic nomenclature of Parechovirus A
Parker, E.; Han, A.; Brouwer, L.; Wolthers, K.; Benschop, K.; Russell, C.
10.1101/2020.08.14.251231 — evolutionary biology — Posted on 2020-08-14
2442 Vitamin D status is heritable and under environment-dependent selection in the wild.
Sparks, A. M.; Johnston, S. E.; Handel, I.; Pilkington, J. G.; Berry, J.; Pemberton, J. M.; Nussey, D. H.; Mellanby, R. J.
10.1101/2020.08.14.251108 — evolutionary biology — Posted on 2020-08-14
2445 The Planarian Anatomy Ontology: A resource to connect data within and across experimental platforms
Sanchez Alvarado, A.; Nowotarski, S.; Davies, E.; Robb, S.; Ross, E.; Matentzoglu, N.; Doddihal, V.; Mir, M.; McClain, M.
10.1101/2020.08.14.251579 — developmental biology — Posted on 2020-08-14
2446 A novel compound that disrupts mitotic spindle poles in human cells
Jaunky, D. B.; Husser, M.; Larocque, K.; Liu, P.; Thampipillai, S.; Forgione, P.; Piekny, A. J.
10.1101/2020.08.14.251058 — cell biology — Posted on 2020-08-14
2448 Methylation of RNA Cap in SARS-CoV-2 captured by serial crystallography
Wilamowski, M.; Sherrell, D.; Minasova, G.; Kim, Y.; Shuvaloca, L.; Lavens, A.; Chard, R.; Maltseva, N.; Jedrzejczak, R.; Rosas-Lemus, M.; Saint, N.; Foster, I. T.; Michalska, K.; Satchell, K. J.; Joachimiak, A.
10.1101/2020.08.14.251421 — molecular biology — Posted on 2020-08-14
2450 SARS-CoV-2 manipulates the SR-B1-mediated HDL uptake pathway for its entry
Wei, C.; Wan, L.; Yan, Q.; Wang, X.; Zhang, J.; Zhang, Y.; Sun, J.; Yang, X.; Gong, J.; Fan, C.; Yang, X.; Wang, Y.; Wang, X.; Li, J.; Yang, H.; Li, H.; Zhang, Z.; Wang, R.; Du, P.; Zong, Y.; Yin, F.; Zhang, W.; Peng, Y.; Lin, H.; Zhang, R.; Chen, W.; Gao, Q.; Cao, Y.; Zhong, H.
10.1101/2020.08.13.248872 — microbiology — Posted on 2020-08-14
2451 A fetal wave of human type-3 γδ T cells with restricted TCR diversity persists into adulthood
Tan, L.; Fichtner, A. S.; Bubke, A.; Odak, I.; Schultze-Florey, C.; Koenecke, C.; Foerster, R.; Jarek, M.; Kaisenberg, C. v.; Borchers, A.; Panzer, U.; Krebs, C.; Ravens, S.; Prinz, I.
10.1101/2020.08.14.248146 — immunology — Posted on 2020-08-14
2453 Canonical EEG Microstate Dynamic Properties and Their Associations with fMRI Signals at Resting Brain
Al Zoubi, O.; Misaki, M.; Tsuchiyagaito, A.; Mayeli, A.; Zotev, V.; Tulsa 1000 Investigators, ; Refai, H.; Paulus, M. P.; Bodurka, J.
10.1101/2020.08.14.251066 — neuroscience — Posted on 2020-08-14
2454 Post-tetanic potentiation lowers the energy barrier for synaptic vesicle fusion independently of Synaptotagmin-1
Huson, V.; Meijer, M.; Dekker, R.; ter Veer, M.; Ruiter, M.; van Weering, J.; Verhage, M.; Cornelisse, L. N.
10.1101/2020.08.14.251322 — neuroscience — Posted on 2020-08-14
2456 SARS-CoV-2 Infection And Longitudinal Fecal Screening In Malayan Tigers (Panthera tigris jacksoni), Amur Tigers (Panthera tigris altaica), And African Lions (Panthera leo krugeri) At The Bronx Zoo, New York, USA
Bartlett, S. L.; Diel, D. G.; Wang, L.; Zec, S.; Laverack, M.; Martins, M.; Caserta, L. C.; Killian, M. L.; Terio, K.; Olmstead, C.; Delaney, M. A.; Stokol, T.; Ivancic, M.; Jenkins-Moore, M.; Ingerman, K.; Teegan, T.; McCann, C.; Thomas, P.; McAloose, D.; Sykes, J. M.; Calle, P. P.
10.1101/2020.08.14.250928 — zoology — Posted on 2020-08-14
2458 Red-light imaging for programmed cell death visualization and quantification in plant-pathogen interactions
Landeo Villanueva, S.; Malvestiti, M. C.; Joosten, M. H. A. J.; van Ieperen, W.; van Kan, J. A. L.
10.1101/2020.08.14.251009 — plant biology — Posted on 2020-08-14
2459 Life story of Tunisian durum wheat landraces revealed by their genetic and phenotypic diversity
Ben Krima, S.; Slim, A.; Gelisse, S.; Kouki, H.; Nadaud, I.; Sourdille, P.; Yahyoui, A.; Ben M'Barek, S.; Suffert, F.; Marcel, T. C.
10.1101/2020.08.14.251157 — plant biology — Posted on 2020-08-14
2460 Phosphorylation of Serine114 of the transcription factor ABSCISIC ACID INSENSITIVE 4 is essential for activity
Eisner, N.; Maymon, T.; Cancho Sanchez, E.; Bar-Zvi, D.; Brodsky, S.; Finkelstein, R. R.; Bar-Zvi, D.
10.1101/2020.08.14.250936 — plant biology — Posted on 2020-08-14
2463 Effective variant filtering and expected candidate variant yield in studies of rare human disease
Pedersen, B. S.; Brown, J. M.; Dashnow, H.; Wallace, A. D.; Velinder, M.; Tvrdik, T.; Mao, R.; Best, H. D.; Bayrak-Toydemir, P.; Quinlan, A. R.
10.1101/2020.08.13.249532 — bioinformatics — Posted on 2020-08-14
2466 A potent neutralizing nanobody against SARS-CoV-2 with inhaled delivery potential
Gai, J.; Ma, L.; Li, G.; Zhu, M.; Qiao, P.; Li, X.; Zhang, H.; Zhang, Y.; Chen, Y.; Ji, W.; Zhang, H.; Cao, H.; Li, X.; Gong, R.; Wan, Y.
10.1101/2020.08.09.242867 — bioengineering — Posted on 2020-08-14
2472 Discriminating lineages of Batrachochytrium dendrobatidis using quantitative PCR
Ghosh, P. N.; Verster, R.; Sewell, T.; O'Hanlon, S.; Brookes, L. M.; Rieux, A.; Garner, T. W.; Weldon, C.; Fisher, M. C.
10.1101/2020.08.14.250787 — ecology — Posted on 2020-08-14
2473 CREB mediates the C. elegans dauer polyphenism through direct and cell-autonomous regulation of TGF-β expression
Park, J.; Oh, H.; Kim, D.-Y.; Cheon, Y.; Park, Y.-J.; Neal, S. J.; Butcher, R. A.; Dar, A. R.; Sengupta, P.; Kim, D.-w.; Kim, K.
10.1101/2020.08.14.250498 — developmental biology — Posted on 2020-08-14
2476 Pleiotropic effect of Lactoferrin in the prevention and treatment of COVID-19 infection: in vivo, in silico and in vitro preliminary evidences
Campione, E.; Lanna, C.; Cosio, T.; Rosa, L.; Conte, M. P.; Iacovelli, F.; Romeo, A.; Falconi, M.; Del Vecchio, C.; Franchin, E.; Lia, M. S.; Minieri, M.; Chiaramonte, C.; Ciotti, M.; Nuccetelli, M.; Terrinoni, A.; Iannuzzi, I.; Coppeda, L.; Magrini, A.; Moricca, N.; Sabatini, S.; Rosapepe, F.; Bartoletti, P. L.; Bernardini, S.; Andreoni, M.; Valenti, P.; Bianchi, L.
10.1101/2020.08.11.244996 — microbiology — Posted on 2020-08-14
2477 Functional immune mapping with deep-learning enabled phenomics applied to immunomodulatory and COVID-19 drug discovery
Cuccarese, M. F.; Earnshaw, B. A.; Heiser, K.; Fogelson, B.; Davis, C. T.; McLean, P. F.; Gordon, H. B.; Skelly, K.-R.; Weathersby, F. L.; Rodic, V.; Quigley, I. K.; Pastuzyn, E. D.; Mendivil, B. M.; Lazar, N. H.; Brooks, C. A.; Carpenter, J.; Probst, B. L.; Jacobson, P.; Glazier, S. W.; Ford, J.; Jensen, J. D.; Campbell, N. D.; Statnick, M. A.; Low, A. S.; Thomas, K. R.; Carpenter, A. E.; Hegde, S. S.; Alfa, R. W.; Victors, M. L.; Haque, I. S.; Chong, Y. T.; Gibson, C. C.
10.1101/2020.08.02.233064 — immunology — Posted on 2020-08-14
2479 Mapping the Human Visual Thalamus and its Cytoarchitectonic Subdivisions Using Quantitative MRI
Mueller-Axt, C.; Eichner, C.; Rusch, H.; Kauffmann, L.; Bazin, P.-L.; Anwander, A.; Morawski, M.; von Kriegstein, K.
10.1101/2020.08.14.250779 — neuroscience — Posted on 2020-08-14
2480 A generative network model of neurodevelopment
Akarca, D.; Vertes, P. E.; Bullmore, E. T.; the CALM team, ; Astle, D. E.
10.1101/2020.08.13.249391 — neuroscience — Posted on 2020-08-14
2481 The effects of regular aerobic exercise on hippocampal structure and function
Hendrikse, J. J.; Chye, Y.; Thompson, S.; Rogasch, N. C.; Suo, C.; Coxon, J.; Yucel, M.
10.1101/2020.08.14.250688 — neuroscience — Posted on 2020-08-14
2482 Use of Therapeutic Drug Monitoring to Characterize Cefepime-Induced Neurotoxicity
Venugopalan, V.; Nys, C.; Hurst, N.; Chen, Y.; Bruzzone, M.; Cherabuddi, K.; Iovine, N. M.; Liu, J.; Al-Shaer, M. H.; Scheetz, M. H.; Rhodes, N. J.; Peloquin, C. A.; Klinker, K. P.
10.1101/2020.08.13.250456 — pharmacology and toxicology — Posted on 2020-08-14
2483 A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer
Nounu, A.; Greenhough, A.; Heesom, K. J.; Richmond, R. C.; Zheng, J.; Weinstein, S. J.; Albanes, D.; Baron, J. A.; Hopper, J. L.; Figueiredo, J. C.; Newcomb, P. A.; Lindor, N. M.; Casey, G.; Platz, E. A.; Le Marchand, L.; Ulrich, C. M.; Li, C. I.; van Duijnhoven, F. J.; Gsur, A.; Campbell, P. T.; Moreno, V.; Vodicka, P.; Vodickova, L.; Brenner, H.; Chang-Claude, J.; Hoffmeister, M.; Sakoda, L. C.; Slattery, M. L.; Schoen, R. E.; Gunter, M. J.; Castellvi-Bel, S.; Rok Kim, H.; Kweon, S.-S.; Chan, A. T.; Li, L.; Zheng, W.; Bishop, D. T.; Buchanan, D. D.; Giles, G. G.; Gruber, S. B.; Rennert, G.;
10.1101/2020.08.14.239871 — cancer biology — Posted on 2020-08-14
2486 Bisbee: A proteomics validated analysis package for detecting differential splicing, identifying splice outliers, and predicting splice event protein effects
Halperin, R. F.; Hedge, A.; Lang, J. D.; Raupach, E. A.; C4RCD Research Group, ; Legendre, C.; Liang, W. S.; LoRusso, P.; Sekulic, A.; Sosman, J. A.; Trent, J. M.; Rangasamy, S.; Pirrotte, P.; Schork, N. J.
10.1101/2020.08.13.250167 — bioinformatics — Posted on 2020-08-14
2487 msiPL: Non-linear Manifold and Peak Learning of Mass Spectrometry Imaging Data Using Artificial Neural Networks
Abdelmoula, W. M.; Lopez, B. G.-C.; Randall, E. C.; Kapur, T.; Sarkaria, J. N.; White, F. M.; Agar, J. N.; Wells, W. M.; Agar, N. Y. R.
10.1101/2020.08.13.250142 — bioinformatics — Posted on 2020-08-14
2489 The proteasome-related Connectase is a fast and specific protein ligase
Fuchs, A. C. D.; Ammelburg, M.; Martin, J.; Hartmann, M. D.; Lupas, A. N.
10.1101/2020.08.14.217505 — biochemistry — Posted on 2020-08-14
2490 Swimming direction of the Glass Catfish, Kryptopterus bicirrhis, is responsive to magnetic stimulation
Hunt, R. D.; Ashbaugh, R. C.; Reimers, M.; Udpa, L.; Saldana De Jimenez, G.; Moore, M.; Gilad, A. A.; Pelled, G.
10.1101/2020.08.13.250035 — animal behavior and cognition — Posted on 2020-08-14
2491 Genome-wide predictions of genetic redundancy in Arabidopsis thaliana
Cusack, S. A.; Wang, P.; Moore, B. M.; Meng, F.; Conner, J. K.; Krysan, P. J.; Lehti-Shiu, M. D.; Shiu, S.-H.
10.1101/2020.08.13.250225 — evolutionary biology — Posted on 2020-08-14
2492 Transient delivery of A-C/EBP protein perturbs differentiation of 3T3-L1 cells and induces preadipocyte marker genes
Rishi, V.; Sharma, N.; Kaur, R.; Yadav, B.; Shah, K.; Pandey, H.; Choudhary, D.; Jain, P.; Aggarwal, A.; Vinson, C.
10.1101/2020.08.13.250324 — molecular biology — Posted on 2020-08-14
2494 Standing on elevated platform changes postural responses during arm movement
Mochizuki, L.; Pennone, J.; Bigongiari, A.; Cosme, R. G.; Cajueiro, M.; Amadio, A. C.
10.1101/2020.08.13.250266 — neuroscience — Posted on 2020-08-14
2500 A comparative analysis of chromatin accessibility in cattle, pig, and mouse tissues
Halstead, M. M.; Kern, C.; Saelao, P.; Wang, Y.; Chanthavixay, G.; Medrano, J. F.; Van Eenennaam, A. L.; Korf, I.; Tuggle, C. K.; Ernst, C. W.; Zhou, H.; ROSS, P. J.
10.1101/2020.08.13.249870 — genomics — Posted on 2020-08-14
2501 Variation in developmental rates is not linked to environmental unpredictability in annual killifishes
Rowinski, P. K.; Sowersby, W.; Näslund, J.; Eckerström-Liedholm, S.; Gotthard, K.; Rogell, B.
10.1101/2020.03.16.993329 — evolutionary biology — Posted on 2020-08-14
2504 DPP9 directly sequesters the NLRP1 C-terminus to repress inflammasome activation
Hollingsworth, L. R.; Sharif, H.; Griswold, A. R.; Fontana, P.; Mintseris, J.; Dagbay, K. B.; Paulo, J. A.; Gygi, S. P.; Bachovchin, D. A.; Wu, H.
10.1101/2020.08.14.246132 — immunology — Posted on 2020-08-14
2506 Intercellular Arc signaling regulates vasodilation
Barragan-Iglesias, P.; De La Pena, J. B.; Lou, T.-F.; Loerch, S.; Prakash, N.; Shukla, T.; Basavarajappa, L.; Song, J.; Megat, S.; Moy, J.; Wanghzou, A.; Ray, P.; Shepherd, J. D.; Hoyt, K.; Steward, O.; Price, T. J.; Campbell, Z. T.
10.1101/2020.08.13.250209 — neuroscience — Posted on 2020-08-14
2508 Consequences of aneuploidy in human fibroblasts with trisomy 21
Hwang, S.; Cavaliere, P.; Li, R.; Zhu, L. J.; Dephoure, N.; Torres, E. M.
10.1101/2020.08.14.251082 — cell biology — Posted on 2020-08-14
2514 How widespread was the Tapanuli orangutan and what led to its decline?
Meijaard, E.; Ni'matullah, S.; Dennis, R.; Sherman, J.; Onrizal, ; Wich, S. A.
10.1101/2020.08.11.246058 — zoology — Posted on 2020-08-14
2521 DREAM represses distinct targets by cooperating with different THAP domain proteins
Gal, C.; Carelli, F. N.; Appert, A.; Cerrato, C.; Huang, N.; Dong, Y.; Murphy, J.; Ahringer, J.
10.1101/2020.08.13.249698 — genomics — Posted on 2020-08-14
2523 The Nature of Genetic Susceptibility to Multiple Sclerosis
Goodin, D. S.; Khankhanian, P.; Gourraud, P.-A.; Vince, N.
10.1101/2020.08.13.249920 — genetics — Posted on 2020-08-14
2529 Ultra-Low Colcemid Doses Induce Microtubule Dysfunction as Revealed by Super-Resolution Microscopy
Rozario, A.; Duwe, S.; Elliott, C.; Hargreaves, R. B.; Dedecker, P.; Whelan, D. R.; Bell, T.
10.1101/2020.08.13.249664 — cell biology — Posted on 2020-08-14
2531 The RNA-binding protein Puf5 buffers mRNA levels against chromatin-mediated changes in nascent transcription
Kochan, D. Z.; Mawer, J. S. P.; Tishinov, K.; Parekh, S.; Maassen, J.; Graef, M.; Spang, A.; Tessarz, P.
10.1101/2020.08.13.249912 — molecular biology — Posted on 2020-08-14
2532 A Strategy to Assess the Cellular Activity of E3 Ligases against Neo-Substrates using Electrophilic Probes
Pinch, B. J.; Buckley, D. L.; Gleim, S.; Brittain, S. M.; Tandeske, L.; D'Alessandro, P. L.; Harvey, E. P.; Hauseman, Z. J.; Schirle, M.; Sprague, E. R.; Forrester, W. C.; Dovala, D.; McGregor, L. M.; Thoma, C. R.
10.1101/2020.08.13.249482 — molecular biology — Posted on 2020-08-14
2533 Population analysis of Legionella pneumophila reveals the basis of resistance to complement-mediated killing
Fitzgerald, J. R.; Wee, B.; Alves, J.; Lindsay, D.; Cameron, R.; Pickering, A.; Gorzynski, J.; Corander, J.; Marttinen, P.; Smith, A.
10.1101/2020.08.14.250670 — microbiology — Posted on 2020-08-14
2535 Machine learning reveals time-varying microbial predictors with complex effects on glucose regulation
Aasmets, O.; Lüll, K.; Lang, J. M.; Pan, C.; Kuusisto, J.; Fischer, K.; Laakso, M.; Lusis, A. J.; Org, E.
10.1101/2020.08.13.250423 — microbiology — Posted on 2020-08-14
2536 Identifying potential hosts of short-branch Microsporidia
Doliwa, A.; Dunthorn, M. E.; Rassoshanska, E.; Mahe, F.; Bass, D.; Ritter, C. D.
10.1101/2020.08.13.249938 — microbiology — Posted on 2020-08-14
2538 Open Science Saves Lives: Lessons from the COVID-19 Pandemic
Besancon, L.; Peiffer-Smadja, N.; Segalas, C.; Jiang, H.; Masuzzo, P.; Smout, C. A.; Deforet, M.; Leyrat, C.
10.1101/2020.08.13.249847 — scientific communication and education — Posted on 2020-08-14
2539 The Mehler reaction site is the Phylloquinone within Photosystem I
Kozuleva, M.; Petrova, A.; Milrad, Y.; Semenov, A.; Ivanov, B.; Redding, K. E.; Yacoby, I.
10.1101/2020.08.13.249367 — plant biology — Posted on 2020-08-14
2540 Effective variant filtering and expected candidate variant yield in studies of rare human disease
Pedersen, B. S.; Brown, J. S.; Dashnow, H.; Wallace, A. D.; Velinder, M.; Tvrdik, T.; Mao, R.; Best, H. D.; Bayrak-Toydemir, P.; Quinlan, A. R.
10.1101/2020.08.13.249532 — bioinformatics — Posted on 2020-08-14
2546 Rapid Parallel Adaptation to Anthropogenic Heavy Metal Pollution
PAPADOPULOS, A. S. T.; Helmstetter, A. J.; Osborne, O. G.; Comeault, A. A.; Wood, D. P.; Straw, E. A.; Mason, L. D.; Fay, M. F.; Parker, J.; Dunning, L. T.; Foote, A. D.; Smith, R. J.; Lighten, J.
10.1101/2020.08.12.248328 — evolutionary biology — Posted on 2020-08-14
2552 Forage stoichiometry predicts the home range size of a small terrestrial herbivore
Rizzuto, M.; Leroux, S.; Vander Wal, E.; Richmond, I. C.; Heckford, T. R.; Balluffi-Fry, J.; Wiersma, Y. F.
10.1101/2020.08.13.248831 — ecology — Posted on 2020-08-14
2556 New models to study plasma cells in mouse based on the restriction of IgJ expression to antibody secreting cells.
Ayala, M. V.; Bonaud, A.; Bender, S.; Lambert, J.-M.; Lechouane, F.; Carrion, C.; Cogne, M.; Pascal, V.; Sirac, C.
10.1101/2020.08.13.249441 — immunology — Posted on 2020-08-14
2564 An antiviral self-replicating molecular heterotroph
Shapiro, A.; Rosenberg, A.; Levy-Zamir, A.; Bassali, L.; Ittah, S.; Abu-Horowitz, A.; Bachelet, I.
10.1101/2020.08.12.248997 — synthetic biology — Posted on 2020-08-14
2571 Charge Interactions in a Highly Charge-depleted Protein
Hervo-Hansen, S.; Hojgaard, C.; Johansson, K. E.; Wang, Y.; Wahni, K.; Young, D.; Messens, J.; Teilum, K.; Lindorff-Larsen, K.; Winther, J. R.
10.1101/2020.06.26.173278 — biochemistry — Posted on 2020-08-14
2573 Suv39h-catalysed H3K9me3 is critical for euchromatic genome organisation and the maintenance of gene transcription
Keenan, C. R.; Coughlan, H. D.; Iannarella, N.; Johanson, T. M.; Chan, W. F.; Garnham, A. L.; Smyth, G. K.; Allan, R. S.
10.1101/2020.08.13.249078 — genomics — Posted on 2020-08-14
2576 UPRmt scales mitochondrial network expansion with protein synthesis via mitochondrial import
Shpilka, T.; Du, Y.; Yung, Q.; Melber, A.; Uma Naresh, N.; Lavelle, J.; Liu, P.; Weidberg, H.; Li, R.; Yu, J.; Zhu, L. J.; Strittmatter, L.; Haynes, C. M.
10.1101/2020.08.12.248161 — molecular biology — Posted on 2020-08-14
2579 Broiler Chickens and Early Life Programming: Microbiome transplant-induced cecal bacteriome dynamics and phenotypic effects
Ramirez, G. A.; Richardson, E.; Clark, J.; Keshri, J.; Drechsler, Y.; Berrang, M. E.; Meinersmann, R. J.; Cox, N. A.; Oakley, B. B.
10.1101/2020.08.13.240572 — microbiology — Posted on 2020-08-14
2580 Immunoreactive peptide maps of SARS-CoV-2 and other human coronaviruses
Mishra, N.; Huang, X.; Joshi, S.; Guo, C.; Ng, J.; Thakkar, R.; Wu, Y.; Dong, X.; Li, Q.; Pinapati, R.; Sullivan, E.; Caciula, A.; Tokarz, R.; Briese, T.; Lu, J.; Lipkin, W. I.
10.1101/2020.08.13.249953 — microbiology — Posted on 2020-08-14
2582 Bacterial gene essentiality under modeled microgravity
Burgos, E.; Vroom, M. M.; Rotman, E. R.; Murphy-Belcaster, M.; Foster, J. S.; Mandel, M. J.
10.1101/2020.08.13.250431 — microbiology — Posted on 2020-08-14
2583 Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodelling superfamily
Liu, J.; Tassinari, M.; Souza, D. P.; Naskar, S.; Noel, J. K.; Bohuszewicz, O.; Buck, M.; Williams, T. A.; Baum, B.; Low, H. H.
10.1101/2020.08.13.249979 — microbiology — Posted on 2020-08-14
2584 A refined set of rRNA-targeted oligonucleotide probes for in situ detection and quantification of ammonia-oxidizing bacteria
Lukumbuzya, M.; Kristensen, J. M.; Kitzinger, K.; Pommerening-Roeser, A.; Nielsen, P. H.; Wagner, M.; Daims, H.; Pjevac, P.
10.1101/2020.05.27.119446 — microbiology — Posted on 2020-08-14
2585 Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion
Papa, G.; Mallery, D.; Albecka, A.; Welch, L.; Cattin-Ortola, J.; Luptak, J.; Paul, D.; McMahon, H.; Goodfellow, I. G.; Carter, A. P.; Munro, S. P.; James, L. C.
10.1101/2020.08.13.243303 — microbiology — Posted on 2020-08-14
2586 Structural and biochemical mechanisms of NLRP1 inhibition by DPP9
Chai, J.; Zhong, F. L.; Huang, M.; zhang, X.; Wang, J.; Wu, B.; Han, Z.; Ann, T. G.; Gong, Q.
10.1101/2020.08.13.250241 — immunology — Posted on 2020-08-14
2589 A standardized head-fixation system for performing large-scale, in-vivo physiological recordings in mice
Groblewski, P.; Sullivan, D.; Lecoq, J.; de Vries, S.; Caldejon, S.; L'Heureux, Q.; Keenan, T.; Roll, K.; Slaughterback, C.; Williford, A.; Farrell, C.
10.1101/2020.01.22.916007 — neuroscience — Posted on 2020-08-14
2590 Structure of the activated Roq1 resistosome directly recognizing the pathogen effector XopQ
Martin, R.; Qi, T.; Zhang, H.; Liu, F.; King, M.; Toth, C.; Nogales, E.; Staskawicz, B. J.
10.1101/2020.08.13.246413 — plant biology — Posted on 2020-08-14
2591 Murine models of renal ischaemia reperfusion injury: An opportunity for refinement using non-invasive monitoring methods
Harwood, R.; Bridge, J.; Ressel, L.; Scarfe, L.; Sharkey, J. W.; Czanner, G.; Kalra, P.; Odudu, A.; Kenny, S.; Wilm, B.; Murray, P.
10.1101/2019.12.17.879742 — physiology — Posted on 2020-08-14
2593 CRISPR-Decryptr reveals cis-regulatory elements from noncoding perturbation screens
Rasmussen, A. W.; Äijö, T.; Gabitto, M. I.; Carriero, N.; Sanjana, N.; Skok, J.; Bonneau, R.
10.1101/2020.08.13.247007 — bioinformatics — Posted on 2020-08-14
2595 FAIRSCAPE: A Framework for FAIR and Reproducible Biomedical Analytics
Levinson, M. A.; Niestroy, J.; Al Manir, S.; Fairchild, K. D.; Lake, D. E.; Moorman, J. R.; Clark, T.
10.1101/2020.08.10.244947 — bioinformatics — Posted on 2020-08-14
2596 The Posterior Insular Cortex is Necessary for the Consolidation of Tone Fear Conditioning
de Paiva, J. P. Q.; Bueno, A. P. A.; dos Santos Corrêa, M.; Oliveira, M. G.; Ferreira, T. L.; Fornari, R. V.
10.1101/2020.08.12.248294 — animal behavior and cognition — Posted on 2020-08-13
2597 Mitogenomic Phylogeny of Callithrix with Special Focus on Human Transferred Taxa
Malukiewicz, J.; Cartwright, R. A.; Curi, N. H.; Dergam, J. A.; Igayara, C. S.; Moreira, S. B.; Molina, C. V.; Nicola, P. A.; Noll, A.; Passamani, M.; Pereira, L. C.; Pissinatti, A.; Ruiz-Miranda, C. R.; Silva, D. L.; Stone, A. C.; Zinner, D.; Roos, C.
10.1101/2020.08.12.247692 — genomics — Posted on 2020-08-14
2598 How robust are cross-population signatures of polygenic adaptation in humans?
Refoyo-Martinez, A.; Liu, S.; Jorgensen, A. M.; Jin, X.; Albrechtsen, A.; Martin, A. R.; Racimo, F.
10.1101/2020.07.13.200030 — genetics — Posted on 2020-08-14
2599 Extensive Genetic Diversity and Host Range of Rodent-borne Coronaviruses
Wang, W.; Lin, X.-D.; Zhang, H.-L.; Wang, M.-R.; Guan, X.-Q.; Holmes, E. C.; Zhang, Y.-Z.
10.1101/2020.08.11.245415 — genetics — Posted on 2020-08-14
2602 Asynchrony between virus diversity and antibody selection limits influenza virus evolution
Morris, D. H.; Petrova, V. N.; Rossine, F. W.; Parker, E.; Grenfell, B. T.; Neher, R.; Levin, S. A.; Russell, C. A.
10.1101/2020.04.27.064915 — evolutionary biology — Posted on 2020-08-13
2604 Action Potentials and Na+ voltage-gated ion channels in Placozoa
Romanova, D. Y.; Smirnov, I. V.; Nikitin, M. A.; Kohn, A. B.; Borman, A.; Malyshev, A.; Balaban, P. M.; Moroz, L. L.
10.1101/2020.08.09.243113 — evolutionary biology — Posted on 2020-08-14
2605 Urban living influences the reproductive success of Darwin's finches in the Galapagos Islands
Harvey, J. A.; Chernicky, K.; Simons, S. R.; Verrett, T. B.; Chaves, J. A.; Knutie, S. A.
10.1101/2020.07.08.193623 — ecology — Posted on 2020-08-13
2607 Nicotinic receptors atlas in the adult human lung
Diabasana, Z.; Perotin, J.-M.; Belgacemi, R.; Ancel, J.; Mulette, P.; Delepine, G.; Gosset, P.; Maskos, U.; Polette, M.; Deslee, G.; Dormoy, V.
10.1101/2020.06.29.176750 — cell biology — Posted on 2020-08-13
2608 Energy Shortage in Human and Mouse Models of SLC4A11-associated Corneal Endothelial Dystrophies
Zhang, W.; Frausto, R.; Chung, D.; Griffis, C. G.; Kao, L.; Chen, A.; Azimov, R.; Sampath, A.; Kurtz, I.; Aldave, A.
10.1101/868281 — cell biology — Posted on 2020-08-13
2610 Direct RNA sequencing reveals m6A modifications on adenovirus RNA are necessary for efficient splicing
Price, A. M.; Hayer, K. E.; McIntyre, A. B. R.; Gokhale, N. S.; Abebe, J. S.; Della Fera, A. N.; Mason, C. E.; Horner, S. M.; Wilson, A. C.; Depledge, D. P.; Weitzman, M. D.
10.1101/865485 — molecular biology — Posted on 2020-08-13
2613 Efferent feedback enforces bilateral coupling of spontaneous activity in the developing auditory system
Wang, Y.; Sanghvi, M.; Gribizis, A.; Zhang, Y.; Song, L.; Morley, B.; Barson, D.; Santos-Sacchi, J.; Navaratnam, D. S.; Crair, M.
10.1101/2020.08.12.248799 — neuroscience — Posted on 2020-08-13
2615 Chondroitinase and antidepressants promote plasticity by releasing TRKB from dephosphorylating control of PTPσ in parvalbumin neurons
Lesnikova, A.; Casarotto, P. C.; Fred, M. S.; Voipio, M.; Winkel, F.; Steinzeig, A.; Antila, H.; Umemori, J.; Biojone, C.; Castren, E.
10.1101/2020.08.13.249615 — neuroscience — Posted on 2020-08-14
2619 SurA is a "Groove-y" Chaperone That Expands Unfolded Outer Membrane Proteins
Marx, D. C.; Plummer, A. M.; Faustino, A. M.; Roskopf, M. A.; Leblanc, M. J.; Devlin, T.; Lessen, H. J.; Amann, B. T.; Fleming, P. J.; Krueger, S.; Fried, S. D.; Fleming, K. G.
10.1101/2019.12.17.878660 — biophysics — Posted on 2020-08-13
2620 Structural basis for PRC2 decoding of active histone methylation marks H3K36me2/3
Finogenova, K.; Bonnet, J.; Poepsel, S.; Schäfer, I. B.; Finkl, K.; Schmid, K.; Litz, C.; Strauss, M.; Benda, C.; Müller, J.
10.1101/2020.04.22.054684 — biochemistry — Posted on 2020-08-13
2622 ATF3 drives senescence by reconstructing accessible chromatin profiles
Zhang, C.; Zhang, X.; Guan, Y.; Huang, X.; Zhang, L.; Tian, X.-L.; Tao, W.
10.1101/2020.08.13.249458 — cell biology — Posted on 2020-08-13
2627 Kinetic analysis reveals the rates and mechanisms of protein aggregation in a multicellular organism
Sinnige, T.; Meisl, G.; Michaels, T. C. T.; Vendruscolo, M.; Knowles, T. P. J.; Morimoto, R. I.
10.1101/2020.08.13.249862 — biophysics — Posted on 2020-08-13
2629 Retention of Lumpy Skin Disease Virus in Stomoxys Spp (Stomoxys Calsitrans, Stomoxys Sitiens, Stomoxys Indica) following intrathoracic inoculation, Diptera: Muscidae.
Issimov, A.; Kutumbetov, L.; Zhanabayev, A.; Kazhgaliyev, N.; Nurgaliyev, B.; Zhubantayev, I.; Akhmetaliyeva, A.; Shalmenov, M.; Kereyev, A.; White, P. J.
10.1101/2020.08.13.249227 — ecology — Posted on 2020-08-13
2631 A Wnt-specific astacin proteinase controls head formation in Hydra
Ziegler, B.; Yiallouros, I.; Trageser, B.; Kumar, S.; Mercker, M.; Kling, S.; Fath, M.; Warnken, U.; Schnoelzer, M.; Holstein, T. W.; Hartl, M.; Marciniak-Czochra, A.; Stetefeld, J.; Stoecker, W.; Oezbek, S.
10.1101/2020.08.13.247569 — developmental biology — Posted on 2020-08-13
2632 PTEN Inhibition Ameliorates Muscle Degeneration and Improves Muscle Function in a Mouse Model of Duchenne Muscular Dystrophy
Yue, F.; Song, C.; Huang, D.; Narayanan, N.; Qiu, J.; Jia, Z.; Yuan, Z.; Oprescu, S. N.; Roseguini, B. T.; Deng, M.; Kuang, S.
10.1101/2020.08.13.249961 — developmental biology — Posted on 2020-08-13
2633 Assessment of Neurovascular Coupling & Cortical Spreading Depression in Mixed Models of Atherosclerosis & Alzheimer's Disease
Shabir, O.; Pendry, B.; Lee, L. M.; Eyre, B.; Sharp, P.; Rebollar, M. A.; Howarth, C.; Heath, P. R.; Wharton, S. B.; Francis, S.; Berwick, J.
10.1101/2020.08.13.249987 — neuroscience — Posted on 2020-08-13
2635 Co-evolutionary signals from Burkholderia pseudomallei population genomics highlight its survival strategy in a hostile environment
Chewapreecha, C.; Pensar, J.; Chattagul, S.; Pesonen, M.; Sangphukieo, A.; Boonklang, P.; Potisap, C.; Koosakulnirand, S.; Feil, E. J.; Dunachie, S.; Chantratita, N.; Limmathurotsakul, D.; Peacock, S. J.; Day, N. P. J.; Parkhill, J.; Thomson, N. R.; Sermswan, R. W.; Corander, J.
10.1101/2020.08.11.245894 — microbiology — Posted on 2020-08-13
2636 Reduction of Short-Chain Fatty Acid-Producing Gut Microbiota Leads to Transition from Rapid-Eye-Movement Sleep Behavior Disorder to Parkinson's Disease
Nishiwaki, H.; Hamaguchi, T.; Ito, M.; Ishida, T.; Maeda, T.; Kashihara, K.; Tsuboi, Y.; Ueyama, J.; Teppei, S.; Mori, H.; Kurokawa, K.; Katsuno, M.; Hirayama, M.; Ohno, K.
10.1101/2020.08.07.242453 — microbiology — Posted on 2020-08-13
2637 OrganoidTracker: efficient cell tracking using machine learning and manual error correction
Kok, R. N. U.; Hebert, L.; Huelsz-Prince, G.; Goos, Y. J.; Zheng, X.; Bozek, K.; Stephens, G. J.; Tans, S. J.; van Zon, J. S.
10.1101/2020.03.18.996421 — bioinformatics — Posted on 2020-08-13
2638 Characterisation of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification
Baddock, H. T.; Brolih, S.; Yosaatmadja, Y.; Ratnaweera, M.; Bielinski, M.; Swift, L.; Cruz-Migoni, A.; Morris, G. M.; Schofield, C. J.; Gileadi, O.; McHugh, P. J.
10.1101/2020.08.13.248211 — biochemistry — Posted on 2020-08-13
2639 The SARS-CoV-2 Spike harbours a lipid binding pocket which modulates stability of the prefusion trimer
Carrique, L.; Duyvesteyn, H. M. E.; Malinaukas, T.; Zhao, Y.; Ren, J.; Zhou, D.; Walter, T. S.; Radecke, J.; Huo, J.; Ruza, R.; Shah, P. N.; Fry, E. E.; Stuart, D. I.
10.1101/2020.08.13.249177 — microbiology — Posted on 2020-08-13
2641 Maraviroc inhibits SARS-CoV-2 multiplication and s-protein mediated cell fusion in cell culture
Risner, K.; Tieu, K. V.; Wang, Y.; Bakovic, A.; Bhalla, N.; Nathan, S.; Conway, D. E.; Macklin, P.; Narayanan, A.
10.1101/2020.08.12.246389 — microbiology — Posted on 2020-08-13
2644 MOTS-c is an Exercise-Induced Mitochondrial-Encoded Regulator of Age-Dependent Physical Decline and Muscle Homeostasis
Reynolds, J. C.; Lai, R. W.; Woodhead, J. S. T.; Joly, J. H.; Mitchell, C. J.; Cameron-Smith, D.; Lu, R.; Cohen, P.; Graham, N. A.; Benayoun, B. A.; Merry, T. L.; Lee, C.
10.1101/2019.12.22.886432 — cell biology — Posted on 2020-08-13
2645 MultiPaths: a Python framework for analyzing multi-layer biological networks using diffusion algorithms
Marin-Llao, J.; Mubeen, S.; Perera-Lluna, A.; Hofmann-Apitius, M.; Picart-Armada, S.; Domingo-Fernandez, D.
10.1101/2020.08.12.243766 — bioinformatics — Posted on 2020-08-13
2647 Malignant assignment of neuronal Na+ leak channel, NALCN: governor of Ca2+ oscillations-encoded invadopodogenesis
Iamshanova, O.; Gordienko, D.; Folcher, A.; Bokhobza, A.; Shapovalov, G.; Mariot, P.; Allart, L.; Desruelles, E.; Spriet, C.; Diez, R.; Oullier, T.; Marionneau-Lambot, S.; Brisson, L.; Geraci, S.; Impheng, H.; Lehenkyi, V.; Haustrate, A.; Mihalache, A.; Gosset, P.; Chadet, S.; Lerondel, S.; Retif, S.; Le Mee, M.; Sobilo, J.; Roger, S.; Fromont, G.; Djamgoz, M.; Clezardin, P.; Monteil, A.; Prevarskaya, N.
10.1101/2020.08.13.249169 — cell biology — Posted on 2020-08-13
2648 Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract
Ortiz Bezara, M. E.; Thurman, A.; Pezzulo, A. A.; Leidinger, M. R.; Klesney-Tait, J. A.; Karp, P. H.; Tan, P.; Wohlford-Lenane, C.; McCray, P. B.; Meyerholz, D. K.
10.1101/2020.04.22.056127 — cell biology — Posted on 2020-08-13
2650 Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins
Gerson, J. E.; Linton, H.; Xing, J.; Sutter, A. B.; Kakos, F. S.; Ryou, J.; Liggans, N.; Sharkey, L.; Safren, N.; Paulson, H. L.; Ivanova, M. I.
10.1101/2020.08.12.248401 — neuroscience — Posted on 2020-08-13
2651 Virtual connectomic datasets in dementia and Alzheimer's Disease using whole-brain network dynamics modelling
Arbabyazd, D. M.; Shen, K.; Wang, Z.; Hofmann-Apitius, M.; McIntosh, A. R.; Battaglia, D.; Jirsa, V.
10.1101/2020.01.18.911248 — neuroscience — Posted on 2020-08-13
2652 EEG-based detection of the locus of auditory attention with convolutional neural networks
Vandecappelle, S.; Deckers, L.; Das, N.; Ansari, A. H.; Bertrand, A.; Francart, T.
10.1101/475673 — neuroscience — Posted on 2020-08-13
2655 Timed mesodermal FGF and BMP govern the multi-step thyroid specification
Haerlingen, B.; Opitz, R.; Vandernoot, I.; Molinaro, A.; Shankar, M.; Gillotay, P.; Trubiroha, A.; Costagliola, S.
10.1101/2020.08.13.249540 — developmental biology — Posted on 2020-08-13
2656 The TPLATE subunit is essential for structural assembly of the endocytic TSET complex
Yperman, K.; Wang, J.; Eeckhout, D.; Winkler, J.; Vu, L.; Vandorpe, M.; Grones, P.; Mylle, E.; Kraus, M.; Merceron, R.; Nolf, J.; Mor, E.; De Bruyn, P.; Loris, R.; Potocky, M.; Savvides, S. N.; De Rybel, B.; De Jaeger, G.; Van Damme, D.; Pleskot, R.
10.1101/2020.08.13.249276 — cell biology — Posted on 2020-08-13
2657 Foam cell induction activates AMPK but uncouples its regulation of autophagy and lysosomal homeostasis
LeBlond, N. D.; Nunes, J. R. C.; Smith, T. K. T.; Robichaud, S.; Gadde, S.; Cote, M.; Kemp, B. E.; Ouimet, M.; Fullerton, M. D.
10.1101/2020.08.13.244640 — cell biology — Posted on 2020-08-13
2659 Chondroitinase and antidepressants promote plasticity by releasing TRKB from dephosphorylating control of PTPσ in parvalbumin neurons
Lesnikova, A.; Casarotto, P. C.; Fred, M. S.; Voipio, M.; Winkel, F.; Steinzeig, A.; Antila, H.; Umemori, J.; Biojone, C.; Castren, E.
10.1101/2020.08.13.249615 — neuroscience — Posted on 2020-08-13
2661 Pleiotropy in FOXC1-attributable phenotypes involves altered ciliation and cilia-dependent signaling
Havrylov, S.; Chrystal, P.; van Baarle, S.; French, C. R.; MacDonald, I. M.; Avasarala, J. R.; Rogers, R. C.; Berry, F. B.; Kume, T.; Waskiewicz, A. J.; Lehmann, O. J.
10.1101/2020.08.13.249334 — genetics — Posted on 2020-08-13
2662 Highly efficient genome modification of cultured primordial germ cells with lentiviral vectors to generate transgenic songbirds
Gessara, I.; Dittrich, F.; Hertel, M.; Hildebrand, S.; Pfeifer, A.; Frankl-Vilches, C.; McGrew, M.; Gahr, M.
10.1101/2020.08.11.245753 — neuroscience — Posted on 2020-08-13
2667 Gene-tree Species-tree Discordance in the Eared Seals is best explained by Incomplete Lineage Sorting following Explosive Radiation in the Southern Hemisphere
Lopes, F.; Oliveira, L. R.; Kessler, A.; Crespo, E.; Cardenas-Alayza, S.; Majluf, P.; Sepulveda, M.; Brownell, R. L.; Franco-Trecu, V.; Paez-Rosas, D.; Chaves, J.; Loch, C.; Robertson, B.; Acevedo-Whitehouse, K.; Elorriaga-Verplancken, F. R.; Kirkman, S. P.; Peart, C. R.; Wolf, J. B. W.; Bonatto, S. L.
10.1101/2020.08.11.246108 — evolutionary biology — Posted on 2020-08-13
2668 Two sides of a coin: a Zika virus mutation selected in pregnant rhesus macaques promotes fetal infection in mice but at a cost of reduced fitness in nonpregnant macaques and diminished transmissibility by vectors
Lemos, D.; Stuart, J. B.; Louie, W.; Singapuri, A.; Ramirez, A. L.; Watanabe, J.; Usachenko, J.; Keesler, R.; Sanchez-San Martin, C.; Li, T.; Martyn, C.; Oliveira, G.; Saraf, S.; Grubaugh, N. D.; Andersen, K.; Thissen, J. B.; Allen, J.; Borucki, M. K.; Tsetsarkin, K. A.; Pletnev, A. G.; Chiu, C. Y.; Van Rompay, K. K. A.; Coffey, L. L.
10.1101/2020.08.11.247411 — microbiology — Posted on 2020-08-13
2672 Aβ-induced NOX2 activation underlies oxidative stress leading to brain hypometabolism and hyperactivity in Alzheimer's disease
Malkov, A.; Popova, I.; Ivanov, A.; Jang, S.-S.; Yoon, S. Y.; Osipov, A.; Huang, Y.; Zilberter, Y.; Zilberter, M.
10.1101/2020.08.12.248492 — neuroscience — Posted on 2020-08-13
2676 Reconciling functional differences in populations of neurons recorded with two-photon imaging and electrophysiology
Siegle, J. H.; Ledochowitsch, P.; Jia, X.; Millman, D.; Ocker, G. K.; Caldejon, S.; Casal, L.; Cho, A.; Denman, D. J.; Durand, S.; Groblewski, P. A.; Heller, G.; Kato, I.; Kivikas, S.; Lecoq, J.; Nayan, C.; Ngo, K.; Nicovich, P. R.; North, K. R.; Ramirez, T. K.; Swapp, J.; Waughman, X.; Williford, A.; Olsen, S. R.; Koch, C.; Buice, M. A.; de Vries, S. E. J.
10.1101/2020.08.10.244723 — neuroscience — Posted on 2020-08-13
2678 Systematic evaluation of genome sequencing as a first-tier diagnostic test for prenatal and pediatric disorders
Lowther, C.; Valkanas, E.; Giordano, J. L.; Wang, H. Z.; Currall, B. B.; O'Keefe, K.; Collins, R. L.; Zhao, X.; Austin-Tse, C. A.; Evangelista, E.; Aggarwal, V.; Lucente, D.; Gauthier, L. D.; Tolonen, C.; Sahakian, N.; An, J.-Y.; Dong, S.; Norton, M. E.; MacKenzie, T.; Devlin, B.; Gilmore, K.; Powell, B.; Brandt, A.; Vetrini, F.; DiVito, M.; Goldstein, D. B.; Sanders, S. J.; MacArthur, D. G.; Hodge, J. C.; O'Donnell-Luria, A.; Rehm, H.; Vora, N.; Levy, B.; Brand, H.; Wapner, R.; Talkowski, M. E.
10.1101/2020.08.12.248526 — genomics — Posted on 2020-08-13
2681 Diverse roles of MAX1 homologues in rice
Marzec, M.; Situmorang, A.; Brewer, P.; Braszewska-Zalewska, A.
10.1101/2020.08.12.248138 — plant biology — Posted on 2020-08-13
2682 Protein arginine methyltransferase 5 promotes metastasis via enhancing EGFR transcription and modulating AKT1 activation by methylation
Huang, L.; Zhang, X.-O.; Verdejo-Torres, O.; Wigglesworth, K.; Sun, X.; Sallis, B.; Moon, D.; Huang, T.; Rozen, E.; Zhang, L.; Wang, G.; Shohet, J. M.; Lee, M. M.; Wu, J. Q.
10.1101/2020.08.12.246660 — cancer biology — Posted on 2020-08-13
2692 The SOD-2 protein is the single active SOD enzyme in C. elegans
Fernando, L. M.; Adeel, S.; Basar, M. A.; Allen, A. K.; Duttaroy, A.
10.1101/2020.08.12.247973 — genetics — Posted on 2020-08-13
2697 Genetic diversity and population structure analyses in the Alpine plum (Prunus brigantina Vill.) confirm its affiliation to the Armeniaca section
Liu, S.; DECROOCQ, S.; Harte, E.; Tricon, D.; Chague, A.; Balakishiyeva, G.; Kostritsyna, T.; Turdiev, T.; Fischer Le Saux, M.; Dallot, S.; GIRAUD, T.; DECROOCQ, V.
10.1101/2020.08.12.247718 — evolutionary biology — Posted on 2020-08-13
2698 Fuzzy Quantification of Common and Rare Species in Ecological Communities (FuzzyQ)
Balbuena, J. A.; Montlleo, C.; Llopis-Belenguer, C.; Blasco-Costa, I.; Sarabeev, V. L.; Morand, S.
10.1101/2020.08.12.247502 — ecology — Posted on 2020-08-13
2700 APC/CFZR-1 Controls ZYG-1 Levels to Regulate Centrosome Assembly
Medley, J. C.; DiPanni, J. R.; Schira, L.; Shaffou, B.; Sebou, B.; SONG, M. H.
10.1101/2020.08.12.248658 — cell biology — Posted on 2020-08-13
2701 Src-dependent NM2A tyrosine-phosphorylation regulates actomyosin dynamics
Brito, C.; Mesquita, F. S.; Osorio, D.; Pereira, J.; Billington, N.; Sellers, J. R.; Cabanes, D.; Xavier de Carvalho, A.; Sousa, S.
10.1101/2020.08.12.246090 — cell biology — Posted on 2020-08-13
2702 Regression dynamic causal modeling for resting-state fMRI
Frässle, S.; Harrison, S. J.; Heinzle, J.; Clementz, B. A.; Tamminga, C. A.; Sweeney, J. A.; Gershon, E. S.; Keshavan, M. S.; Pearlson, G. D.; Powers, A.; Stephan, K. E.
10.1101/2020.08.12.247536 — neuroscience — Posted on 2020-08-13
2703 Visualization of Phase-Amplitude Coupling Using Rhythmic High-Frequency Activity
Hashimoto, H.; Khoo, H. M.; Yanagisawa, T.; Tani, N.; Oshino, S.; Kishima, H.; Hirata, M.
10.1101/2020.08.12.247775 — neuroscience — Posted on 2020-08-13
2704 L1CAM is not Associated with Extracellular Vesicles in Human Cerebrospinal Fluid or Plasma
Norman, M.; Ter-Ovanesyan, D.; Trieu, W.; Lazarovits, R.; Kowal, E. J. K.; Lee, J. H.; Chen-Plotkin, A. S.; Regev, A.; Church, G. M.; Walt, D. R.
10.1101/2020.08.12.247833 — neuroscience — Posted on 2020-08-13
2706 Action potentials induce biomagnetic fields in Venus flytrap plants
Fabricant, A.; Iwata, G. Z.; Scherzer, S.; Bougas, L.; Rolfs, K.; Jodko-Władzinska, A.; Voigt, J.; Hedrich, R.; Budker, D.
10.1101/2020.08.12.247924 — plant biology — Posted on 2020-08-13
2707 Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments
Talwelkar, S. S.; Mäyranpää, M. I.; Soraas, L.; Potdar, S.; Bao, J.; Hemmes, A.; Linnavirta, N.; Lomo, J.; Räsänen, J.; Knuuttila, A.; Wennerberg, K.; Verschuren, E. W.
10.1101/2020.08.12.247817 — cancer biology — Posted on 2020-08-13
2710 MACMIC Reveals Dual Role of CTCF in Epigenetic Regulation of Cell Identity Genes
Wang, G.; Xia, B.; Zhou, M.; Lv, J.; Zhao, D.; Li, Y.; Bu, Y.; Wang, X.; Cooke, J. P.; Cao, Q.; Lee, M.; Zhang, L.; Chen, K.
10.1101/2020.08.12.247361 — bioinformatics — Posted on 2020-08-13
2711 Significantly improving the quality of genome assemblies through curation
Howe, K.; Chow, W.; Collins, J.; Pelan, S.; Pointon, D.-L.; Sims, Y.; Torrance, J.; Tracey, A.; Wood, J.
10.1101/2020.08.12.247734 — bioinformatics — Posted on 2020-08-13
2719 Postembryonic screen for mutations affecting spine development in zebrafish
GRAY, R.; Gonzalez, R.; Ackerman, S. D.; Minowa, R. C.; Griest, J. F.; Bayrak, M. N.; Troutwine, B. R.; Canter, S.; Monk, K. R.; Sepich, D. S.; Solnica-Krezel, L.
10.1101/2020.08.12.248716 — developmental biology — Posted on 2020-08-12
2721 Creb5 establishes the competence for Prg4 expression in articular cartilage
Zhang, C.-H.; Gao, Y.; Jadhav, U.; Hung, H.-H.; Holton, K. M.; Grodzinsky, A. J.; Shivdasani, R. A.; Lassar, A. B.
10.1101/2020.08.12.248609 — molecular biology — Posted on 2020-08-12
2722 Differential thermotolerance adaptation between species of Coccidioides
Mead, H. L.; Hamm, P. S.; Shaffer, I. N.; de Melo Teixeira, M.; Wendel, C.; Wiederhold, N. P.; Thompson, G. R.; Muniz-Salazar, R.; Castanon-Olivares, L. R.; Keim, P.; Plude, C.; Terriquez, J.; Galgiani, J. N.; Orbach, M. J.; Barker, B. M.
10.1101/2020.08.12.247635 — microbiology — Posted on 2020-08-12
2723 Molecular architecture of the SARS-CoV-2 virus
Yao, H.; Song, Y.; Chen, Y.; Wu, N.; Xu, J.; Sun, C.; Zhang, J.; Weng, T.; Zhang, Z.; Wu, Z.; Cheng, L.; Shi, D.; Lu, X.; Lei, J.; Crispin, M.; Shi, Y.; Li, L.; Li, S.
10.1101/2020.07.08.192104 — microbiology — Posted on 2020-08-12
2725 Evidence of interaction between humoral immunity and drug half-life in determining treatment outcome for artemisinin combination therapy in high transmission settings in western Kenya
Andagalu, B.; Lu, P.; Onyango, I.; Bergmann-Leitner, E.; Wasuna, R.; Odhiambo, G.; Chebone-Bore, L.; Ingasia, L. A.; Opot, B.; Cheruiyot, A.; Yeda, R.; Okudo, C.; Okoth, R.; Campo, J.; Wallqvist, A.; Akala, H.; Ochiel, D.; Ogutu, B.; Chaudhury, S.; Kamau, E.
10.1101/2020.08.12.248724 — bioinformatics — Posted on 2020-08-12
2726 The Posterior Insular Cortex is Necessary for the Consolidation of Tone Fear
de Paiva, J. P. Q.; Bueno, A. P. A.; dos Santos Corrêa, M.; Oliveira, M. G.; Ferreira, T. L.; Fornari, R. V.
10.1101/2020.08.12.248294 — animal behavior and cognition — Posted on 2020-08-12
2727 Interhemispheric transfer of working memories
Brincat, S. L.; Donoghue, J. A.; Mahnke, M. K.; Kornblith, S.; Lundqvist, M.; Miller, E. K.
10.1101/2020.08.12.248203 — neuroscience — Posted on 2020-08-12
2729 Efferent feedback enforces bilateral coupling of spontaneous activity in the developing auditory system
Wang, Y.; Sanghvi, M.; Gribizis, A.; Zhang, Y.; Song, L.; Morley, B.; Barson, D.; Santos-Sacchi, J.; Navaratnam, D. S.; Crair, M.
10.1101/2020.08.12.248799 — neuroscience — Posted on 2020-08-12
2730 Single cell 3'UTR analysis identifies changes in alternative polyadenylation throughout neuronal differentiation and in autism
Goepferich, M.; George, N. O.; Domingo Muelas, A.; Bizyn, A.; Pascual, R.; Fijalkowska, D.; Kalamakis, G.; Müller, U.; Krijgsveld, J.; Mendez, R.; Farinas, I.; Huber, W.; Anders, S.; Martin-Villalba, A.
10.1101/2020.08.12.247627 — neuroscience — Posted on 2020-08-12
2733 Target deconvolution using in vitro evolution in haploid human cells
Jado, J. C.; Dow, M.; Carolino, K.; Fonseca, G.; Ideker, T.; Carter, H.; Winzeler, E.
10.1101/2020.03.17.982181 — genomics — Posted on 2020-08-12
2734 Does deterministic coexistence theory matter in a finite world?
Schreiber, S.; Levine, J. M.; Godoy, O.; Kraft, N.; Hart, S.
10.1101/290882 — ecology — Posted on 2020-08-12
2736 Investigation of white spot syndrome virus (WSSV) infection in wild crustaceans in the Bohai Sea
Xu, T.; Shan, X.; Yang, T.; Teng, G.; Wu, Q.; Wang, C.; Tang, K. F. J.; Jin, X.; Zhang, Q.
10.1101/2020.08.12.247486 — microbiology — Posted on 2020-08-12
2740 Preclinical modeling of surgery and steroid therapy for glioblastoma reveals changes in immunophenotype that are associated with tumor growth and outcome
Otvos, B.; Alban, T. J.; Grabowski, M. M.; Bayik, D.; Mulkearns-Hubert, E. E.; Radivoyevitch, T.; Rabljenovic, a.; Johnson, S.; Androjna, C.; Mohammadi, A. M.; Barnett, G.; Ahluwalia, M. S.; Vogelbaum, M. A.; Fecci, P. E.; Lathia, J. D.
10.1101/2020.08.12.248443 — cancer biology — Posted on 2020-08-12
2741 Structural basis for transcription complex disruption by the Mfd translocase
Kang, J. Y.; Llewellyn, E.; Chen, J.; Olinares, P. D. B.; Brewer, J.; Chait, B. T.; Campbell, E. A.; Darst, S. A.
10.1101/2020.08.12.248500 — biophysics — Posted on 2020-08-12
2745 The Landscape of Precision Cancer Combination Therapy: A Single-Cell Perspective
Ahmadi, S.; Sukprasert, P.; Vegesna, R.; Artzi, N.; Khuller, S.; Schaffer, A. A.; Ruppin, E.
10.1101/2020.01.28.923532 — bioinformatics — Posted on 2020-08-12
2746 Electronic blood vessel
Cheng, S.; Hang, C.; Ding, L.; Jia, L.; Tang, L.; Mou, L.; Qi, J.; Dong, R.; Zheng, W.; Zhang, Y.; Jiang, X.
10.1101/2020.05.19.103457 — bioengineering — Posted on 2020-08-12
2747 An opened pre-40S platform enables regulation of Fap7 late in ribosomal assembly
Rai, J.; Parker, M. D.; Huang, H.; Choi, S.; Ghalei, H.; Johnson, M. C.; Karbstein, K.; Stroupe, M. E.
10.1101/617910 — biochemistry — Posted on 2020-08-12
2748 The Contributions of the Allopolyploid Parents of the Mesopolyploid Brassiceae are Evolutionarily Distinct but Functionally Compatible
Hao, Y.; Mabry, M. E.; Edger, P.; Freeling, M.; Zheng, C.; Jin, L.; VanBuren, R.; Colle, M.; An, H.; Abrahams, R. S.; Qi, X.; Barry, K.; Daum, C.; Shu, S.; Schmutz, J.; Sankoff, D.; Barker, M. S.; Lyons, E.; Pires, J. C.; Conant, G. C.
10.1101/2020.08.10.245258 — genomics — Posted on 2020-08-12
2750 Social fluidity mobilizes contagion in human and animal populations
Colman, E.; Colizza, V.; Hanks, E. M.; Hughes, D. P.; Bansal, S.
10.1101/170266 — ecology — Posted on 2020-08-12
2751 Toward a Monte Carlo Approach to Selecting Climate Variables in MaxEnt: A Case Study Using Cassin's Sparrow (Peucaea cassinii)
Schnase, J. L.; Carroll, M. L.; Gill, R. L.; Tamkin, G. S.; Li, J.; Strong, S. L.; Maxwell, T. P.; Aronne, M. E.
10.1101/2020.07.15.202945 — ecology — Posted on 2020-08-12
2752 De novo synthesis and salvage pathway coordinately regulates polyamine homeostasis and determines T cell proliferation and function.
Wu, R.; Chen, X.; Kang, S.; Wang, T.; Gnanaprakasam, J. R.; Yao, Y.; Liu, L.; Zheng, S.; Fan, G.; Burns, M.; Wang, R.
10.1101/2020.04.29.068759 — cell biology — Posted on 2020-08-12
2753 KIAA1841, a novel SANT and BTB domain-containing protein, inhibits class switch recombination
Zheng, S.; Matthews, A. J.; Rahman, N.; Herrick-Reynolds, K.; Choi, J. E.; Sible, E.; Ng, Y. K.; Rhodes, D.; Elledge, S. J.; Vuong, B. Q.
10.1101/2020.08.12.247809 — molecular biology — Posted on 2020-08-12
2757 KSHV-encoded vCyclin can modulate HIF1α levels to promote DNA replication in hypoxia
Singh, R. K.; Pei, Y.; Lamplugh, Z. L.; Sun, K.; Yuan, Y.; Lieberman, P.; You, J.; Robertson, E. S.
10.1101/2020.08.12.248005 — microbiology — Posted on 2020-08-12
2764 A genome-wide screen in macrophages identifies new regulators of IFNγ-inducible MHCII that contribute to T cell activation
Kiritsy, M. C.; Ankley, L. M.; Trombley, J. D.; Huizinga, G. P.; Lord, A. E.; Orning, P.; Elling, R.; Fitzgerald, K. A.; Olive, A.
10.1101/2020.08.12.248252 — immunology — Posted on 2020-08-12
2765 Interleukin-10 suppression enhances T-cell antitumor immunity and responses to checkpoint blockade in chronic lymphocytic leukemia
Rivas, J. R.; Alhakeem, S. S.; Liu, Y.; Eckenrode, J. M.; Marti, F.; Collard, J. P.; Zhang, Y.; Shaaban, K. A.; Muthusamy, N.; Hildebrandt, G. C.; Fleischman, R. A.; Chen, L.; Thorson, J. S.; Leggas, M.; Bondada, S.
10.1101/2020.07.15.204560 — immunology — Posted on 2020-08-12
2767 CAP1 and cofilin1 cooperate in neuronal actin dynamics, growth cone function and neuron connectivity
Rust, M. B.; Schneider, F.; Duong, T.-A.; Metz, I.; Winkelmeier, J.; Huebner, C.; Endesfelder, U.
10.1101/2020.08.12.247932 — neuroscience — Posted on 2020-08-12
2768 Motor learning in real-world pool billiards
Haar, S.; van Assel, C. M.; Faisal, A. A.
10.1101/612218 — neuroscience — Posted on 2020-08-12
2770 The developing Human Connectome Project (dHCP) automated resting-state functional processing framework for newborn infants.
Fitzgibbon, S. P.; Harrison, S. J.; Jenkinson, M.; Baxter, L.; Robinson, E. C.; Bastiani, M.; Bozek, J.; Karolis, V.; Cordero Grande, L.; Price, A. N.; Hughes, E.; Makropoulos, A.; Passerat-Palmbach, J.; Schuh, A.; Gao, J.; Farahibozorg, S.-R.; O'Muircheartaigh, J.; Ciarrusta, J.; O'Keeffe, C.; Brandon, J.; Arichi, T.; Rueckert, D.; Hajnal, J. V.; Edwards, A. D.; Smith, S. M.; Duff, E.; Andersson, J.
10.1101/766030 — neuroscience — Posted on 2020-08-12
2771 High Gamma Cortical Processing of Continuous Speech in Younger and Older Listeners
Kulasingham, J. P.; Brodbeck, C.; Presacco, A.; Kuchinsky, S. E.; Anderson, S.; Simon, J. Z.
10.1101/2019.12.19.883314 — neuroscience — Posted on 2020-08-12
2774 Coronacept - a potent immunoadhesin against SARS-CoV-2
Cohen-Dvashi, H.; Weinstein, J.; Katz, M.; Eilon, M.; Mor, Y.; Shimon, A.; Strobelt, R.; Shemesh, M.; Fleishman, S. J.; Diskin, R.
10.1101/2020.08.12.247940 — bioengineering — Posted on 2020-08-12
2775 Kinesin-1 motility traced by an activity-based precipitating dye
Angerani, S.; Lindberg, E.; Klena, N.; Bleck, C. K. E.; Aumeier, C.; Winssinger, N.
10.1101/2020.08.12.247544 — biochemistry — Posted on 2020-08-12
2776 Bimodal evolution of Src and Abl kinase substrate specificity revealed using mammalian cell extract as substrate pool
Finneran, P.; Soucheray, M.; Wilson, C.; Otten, R.; Buosi, V.; Krogan, N. J.; Swaney, D.; Theobald, D.; Kern, D.
10.1101/2020.08.12.248104 — biochemistry — Posted on 2020-08-12
2778 TRIM28 regulates SARS-CoV-2 cell entry by targeting ACE2
Wang, Y.; Fan, Y.; Huang, Y.; Du, T.; Liu, Z.; Huang, D.; Wang, Y.; Wang, N.; Zhang, P.
10.1101/2020.08.12.247825 — molecular biology — Posted on 2020-08-12
2779 Membrane Nanoparticles Derived from ACE2-rich Cells Block SARS-CoV-2 Infection
Wang, C.; Wang, S.; Chen, Y.; Zhao, J.; Han, S.; Zhao, G.; Kang, J.; Liu, Y.; Wang, L.; Wang, X.; Xu, Y.; Wang, S.; Huang, Y.; Wang, J.; Zhao, J.
10.1101/2020.08.12.247338 — microbiology — Posted on 2020-08-12
2781 Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2
Walls, A. C.; Fiala, B.; Schaefer, A.; Wrenn, S.; Pham, M. N.; Murphy, M.; Tse, L. V.; Shehata, L.; O'Connor, M. A.; Chen, C.; Navarro, M. J.; Miranda, M. C.; Pettie, D.; Ravichandran, R.; Kraft, J. C.; Ogohara, C.; Palser, A.; Chalk, S.; Lee, E.-C.; Kepl, E.; Chow, C. M.; Sydeman, C.; Hodge, E. A.; Brown, B.; Fuller, J. T.; Dinnon, K.; Gralinski, L.; Leist, S. R.; Gully, K. L.; Lewis, T. B.; Guttman, M.; Chu, H. Y.; Lee, K. K.; Fuller, D. H.; Baric, R. S.; Kellam, P.; Carter, L.; Pepper, M.; Sheahan, T. P.; Veesler, D.; King, N. P.
10.1101/2020.08.11.247395 — immunology — Posted on 2020-08-12
2783 MultiPaths: a Python framework for analyzing multi-layer biological networks using diffusion algorithms
Marin-Llao, J.; Mubeen, S.; Perera-Lluna, A.; Hofmann-Apitius, M.; Picart-Armada, S.; Domingo-Fernandez, D.
10.1101/2020.08.12.243766 — bioinformatics — Posted on 2020-08-12
2786 Curcumin-Sophorolipid nano-conjugate inhibits Candida albicans filamentation and biofilm development
Rajasekar, V.; Darne, P.; Prabhune, A.; Kao, R. Y. T.; Solomon, A. P.; Ramage, G.; Samaranayake, L.; Neelakantan, P.
10.1101/2020.08.12.244186 — microbiology — Posted on 2020-08-12
2794 Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs
Kim, J. H.; Megquier, K. J.; Thomas, R.; Sarver, A. L.; Song, J. M.; Kim, Y. T.; Schulte, A. J.; Cheng, N.; Linden, M. A.; Murugan, P.; Oseth, L.; Foster, C. L.; Elvers, I.; Swofford, R.; Turner-Maier, J.; Karlsson, E. K.; Breen, M.; Lindblad-Toh, K.; Modiano, J. F.
10.1101/2020.08.11.246777 — cancer biology — Posted on 2020-08-12
2795 Single-cell lineage and transcriptome reconstruction of metastatic cancer reveals selection of aggressive hybrid EMT states
Simeonov, K. P.; Byrns, C. N.; Clark, M. L.; Norgard, R. J.; Martin, B.; Stanger, B. Z.; McKenna, A.; Shendure, J.; Lengner, C. J.
10.1101/2020.08.11.245787 — cancer biology — Posted on 2020-08-12
2796 Multimodal Label-free Monitoring of Adipogenic Stem Cell Differentiation using Endogenous Optical Biomarkers
Mehta, N.; Shaik, S.; Prasad, A.; Chaichi, A.; Sahu, S. P.; Hasan, S. M. A.; Donnarumma, F.; Murray, K. K.; Devireddy, R.; Gartia, M. R.
10.1101/2020.08.12.246322 — biophysics — Posted on 2020-08-12
2800 Tutorial: Assessing metagenomics software with the CAMI benchmarking toolkit
Meyer, F.; Lesker, T. R.; Koslicki, D.; Fritz, A.; Gurevich, A.; Darling, A. E.; Sczyrba, A.; Bremges, A.; McHardy, A. C.
10.1101/2020.08.11.245712 — bioinformatics — Posted on 2020-08-12
2804 Critical Assessment of Protein Intrinsic Disorder Prediction
Necci, M.; Piovesan, D.; CAID Predictors, ; DisProt Curators, ; Tosatto, S. C. E.
10.1101/2020.08.11.245852 — bioinformatics — Posted on 2020-08-12
2805 Deep reinforcement learning for modeling human locomotion control in neuromechanical simulation
Song, S.; Kidzinski, Łukasz; Peng, X. B.; Ong, C.; Hicks, J. L.; Levine, S.; Atkeson, C.; Delp, S.
10.1101/2020.08.11.246801 — bioengineering — Posted on 2020-08-12
2811 Molecular signatures of sexual communication in the phlebotomine sand flies
Hickner, P. V.; Timoshevskaya, N.; Nowling, R. J.; Labbe, F.; Nguyen, A. D.; McDowell, M. A.; Spiegel, C. N.; Syed, Z.
10.1101/2020.08.11.247155 — evolutionary biology — Posted on 2020-08-12
2813 Geographic potential of the world largest hornet, Vespa mandarinia Smith (Hymenoptera: Vespidae), worldwide and particularly in North America
Nunez-Penichet, C.; Osorio-Olvera, L.; Gonzalez, V. H.; Cobos, M. E.; Jimenez, L.; DeRaad, D. A.; Alkishe, A.; Contreras-Diaz, R.; Nava-Bolanos, A.; Utzumi, K.; Ashraf, U.; Adeboje, A.; Peterson, A. T.; Soberon, J.
10.1101/2020.08.11.246991 — ecology — Posted on 2020-08-12
2814 Endothelial Cell Cycle State Determines Propensity for Arterial-Venous Fate
Chavkin, N. W.; Genet, G.; Poulet, M.; Genet, N.; Marziano, C.; Vasavada, H.; Nelson, E. A.; Kour, A.; McDonnell, S. P.; Huba, M.; Walsh, K.; Hirschi, K. K.
10.1101/2020.08.12.246512 — developmental biology — Posted on 2020-08-12
2815 A single-cell method to map higher-order 3D genome organization in thousands of individual cells reveals structural heterogeneity in mouse ES cells
Arrastia, M. V.; Jachowicz, J. W.; Ollikainen, N.; Curtis, M. S.; Lai, C.; Quinodoz, S.; Selck, D. A.; Guttman, M.; Ismagilov, R. F.
10.1101/2020.08.11.242081 — molecular biology — Posted on 2020-08-12
2816 Transcriptome profiling of ulcerative colitis mouse model suggests biomarkers and therapeutic targets for human colitis
Yarani, R.; Palasca, O.; Doncheva, N. T.; Anthon, C.; Pilecki, B.; Svane, C. A. S.; Mirza, A. H.; Litman, T.; Holmskov, U.; Bang-Berthelsen, C. H.; Vilien, M.; Jensen, L. J.; Gorodkin, J.; Pociot, F.
10.1101/2020.08.12.225458 — molecular biology — Posted on 2020-08-12
2817 Wine terroir and the soil microbiome: an amplicon sequencing-based assessment of the Barossa Valley and its sub-regions
Zhou, J.; Cavagnaro, T.; De Bei, R.; Nelson, T. M.; Stephen, J. R.; Metcalfe, A.; Gilliham, M. M.; Breen, J.; Collins, C.; Rodriguez Lopez, C. M.
10.1101/2020.08.12.246447 — microbiology — Posted on 2020-08-12
2818 Characterization of a new Leishmania major isolate for use in a controlled human infection model
Ashwin, H.; Sadlova, J.; Vojtkova, B.; Becvar, T.; Lypaczewski, P.; Schwartz, E.; Greensted, E.; Van Bocxlaer, K.; Pasin, M.; Lipinski, K.; Parkash, V.; Matlashewski, G.; Layton, A.; Lacey, C.; Jaffe, C.; Volf, P.; Kaye, P.
10.1101/2020.08.12.245936 — microbiology — Posted on 2020-08-12
2820 Human neonatal B cell immunity differs from the adult version by conserved Ig repertoires and rapid, but transient response dynamics
Budeus, B.; Kibler, A.; Brauser, M.; Homp, E.; Bronischewski, K.; Ross, A.; Goergens, A.; Weniger, M. A.; Dunst, J.; Kreslavskiy, T.; Vitoriano, S.; Murke, F.; Oakes, C. C.; Rusch, P.; Andrikos, D.; Kern, P.; Koeniger, A.; Lindemann, M.; Johansson, P.; Hansen, W.; Lundell, A.-C.; Rudin, A.; Duerig, J.; Giebel, B.; Hoffmann, D.; Kueppers, R.; Seifert, M.
10.1101/2020.08.11.245985 — immunology — Posted on 2020-08-12
2823 FAM19A5l affects mustard oil-induced peripheral nociception in zebrafish
Jeong, I.; Yun, S.; Shahapal, A.; Cho, E. B.; Hwang, S. W.; Seong, J. Y.; Park, H.-C.
10.1101/2020.08.11.245738 — neuroscience — Posted on 2020-08-12
2826 Comparative Neuroanatomy of the Lumbosacral Spinal Cord of the Rat, Cat, Pig, Monkey, and Human
Toossi, A.; Bergin, B.; Marefatallah, M.; Parhizi, B.; Tyreman, N.; Everaert, D. G.; Rezaei, S.; Seres, P.; Gatenby, J. C.; Perlmutter, S. I.; Mushahwar, V. K.
10.1101/2020.08.11.246165 — neuroscience — Posted on 2020-08-12
2829 The chromatin remodeler ISWI acts during Drosophila development to regulate adult sleep
Gong, N. N.; Chakravarti Dilley, L.; Williams, C. E.; Moscato, E. H.; Szuperak, M.; Wang, Q.; Jensen, M.; Girirajan, S.; Tan, T. Y.; Deardorff, M. A.; Li, D.; Song, Y.; Kayser, M. S.
10.1101/2020.08.11.247080 — neuroscience — Posted on 2020-08-12
2830 Connectome-mediated prediction of future tau-PET burden in Alzheimer's disease
Damasceno, P. F.; La Joie, R.; Shcherbinin, S.; Southekal, S.; Kotari, V.; Higgins, I. A.; Rabinovici, G. D.; Mintun, M. A.; Raj, A.
10.1101/2020.08.11.246496 — neuroscience — Posted on 2020-08-12
2834 Starburst amacrine cells amplify optogenetic visual restoration through gap junctions in the murine retina
Katada, Y.; Kunimi, H.; Kobayashi, K.; Okano, H.; Tanaka, K. F.; Tsubota, K.; Kurihara, T.
10.1101/2020.08.11.246686 — neuroscience — Posted on 2020-08-12
2835 Age-related alterations in prelimbic cortical neuron Arc expression vary by behavioral state and cortical layer
Hernandez, A. R.; Truckenbrod, L. M.; Barrett, M. E.; Lubke, K. N.; Clark, B. J.; Burke, S. N.
10.1101/2020.08.11.247262 — neuroscience — Posted on 2020-08-12
2838 Light-mediated discovery of surfaceome nanoscale organization and intercellular receptor interaction networks
Müller, M.; Gräbnitz, F.; Barandun, N.; Shen, Y.; Vetterli, S. U.; Mondal, M.; Prudent, J. R.; Severin, Y.; van Oostrum, M.; Hofmann, R.; Sarott, R.; Nesvizhskii, A. I.; Carreira, E. M.; Bode, J.; Snijder, B.; Robinson, J. A.; Loessner, M. J.; Oxenius, A.; Wollscheid, B.
10.1101/2020.08.11.246652 — systems biology — Posted on 2020-08-12
2840 IGF targeting perturbs global replication through ribonucleotide reductase dysfunction
Rieunier, G.; Wu, X.; Harris, L.; Mills, J.; Nandakumar, A.; Colling, L.; Seraia, E.; Hatch, S. B.; Ebner, D.; Folkes, L.; Weyer-czernilofsky, U.; Bogenrieder, T.; Ryan, A. J.; Macaulay, V. M.
10.1101/2020.08.11.245886 — cancer biology — Posted on 2020-08-12
2841 Diffusive dynamics of Aspartate α-decarboxylase (ADC) liganded with D-serine in aqueous solution
Raskar, T.; Niebling, S.; Devos, J. M.; Yorke, B. A.; Härtlein, M.; Huse, N.; Forsyth, T. V.; Seydel, T.; Pearson, A. R.
10.1101/2020.08.11.244939 — biophysics — Posted on 2020-08-12
2843 Besca, a single-cell transcriptomics analysis toolkit to accelerate translational research
Maedler, S. C.; Julien-Laferriere, A.; Wyss, L.; Phan, M.; Kang, A. S. W.; Ulrich, E.; Schmucki, R.; Zhang, J. D.; Ebeling, M.; Badi, L.; Kam-Thong, T.; Schwalie, P. C.; Hatje, K.
10.1101/2020.08.11.245795 — bioinformatics — Posted on 2020-08-12
2844 PairGP: Gaussian process modeling of longitudinal data from paired multi-condition studies
Vantini, M.; Mannerström, H.; Rautio, S.; Ahlfors, H.; Stockinger, B.; Lähdesmäki, H.
10.1101/2020.08.11.245621 — bioinformatics — Posted on 2020-08-12
2846 Conformational changes and channel gating induced by CO2 binding to Connexin26
Brotherton, D. H.; Savva, C.; Ragan, T.; Linthwaite, V.; Cann, M.; Dale, N.; Cameron, A. D.
10.1101/2020.08.11.243964 — biochemistry — Posted on 2020-08-12
2848 Adolescent Alcohol Binge-Drinking Insidiously Impairs Adult Behavior In Mice
Van Hees, L.; Didone, V.; Charlet-Briar, M.; Thirion, C.; Van Ingelgom, T.; Quertemont, E.; Nguyen, L.; Laguesse, S.
10.1101/2020.08.11.245878 — animal behavior and cognition — Posted on 2020-08-12
2850 Backstepping mechanism of kinesin-1
Toleikis, A.; Carter, N. J.; Cross, R. A.
10.1101/838433 — biophysics — Posted on 2020-08-12
2853 Obesity promotes glucocorticoid-dependent muscle atrophy in male C57BL/6J mice.
Gunder, L. C.; Harvey, I.; Redd, J. R.; Davis, C. S.; AL-Tamimi, A.; Brooks, S. V.; Bridges, D.
10.1101/2020.08.11.247106 — physiology — Posted on 2020-08-12
2854 Highly-parallel, microfluidics-based force spectroscopy on single motor proteins
Urbanska, M.; Lüdecke, A.; Walter, W. J.; van Oijen, A. M.; Duderstadt, K. E.; Diez, S.
10.1101/2020.08.11.245910 — biophysics — Posted on 2020-08-12
2855 The Contributions of the Allopolyploid Parents of the Mesopolyploid Brassiceae are Evolutionarily Distinct but Functionally Compatible
Hao, Y.; Mabry, M. E.; Edger, P.; Freeling, M.; Zheng, C.; Jin, L.; VanBuren, R.; Colle, M.; An, H.; Abrahams, R. S.; Qi, X.; Barry, K.; Daum, C.; Shu, S.; Schmutz, J.; Sankoff, D.; Barker, M. S.; Lyons, E.; Pires, J. C.; Conant, G. C.
10.1101/2020.08.10.245258 — genomics — Posted on 2020-08-12
2856 Robust Benchmark Structural Variant Calls of An Asian Using the State-of-Art Long Fragment Sequencing Technologies
Du, X.; Li, L.; Liang, F.; Liu, S.; Zhang, W.; Sun, S.; Sun, Y.; Fan, F.; Wang, L.; Liang, X.; Qiu, W.; Fan, G.; Wang, O.; Yang, W.; Zhang, J.; Xiao, Y.; Wang, Y.; Wang, D.; Qu, S.; Chen, F.; Huang, J.
10.1101/2020.08.10.245308 — genomics — Posted on 2020-08-12
2858 Chemical-genetic interactions with the proline analog L-azetidine-2-carboxylic acid in Saccharomyces cerevisiae
Berg, M. D.; Zhu, Y.; Isaacson, J.; Genereaux, J.; Loll-Krippleber, R.; Brown, G. W.; Brandl, C. J.
10.1101/2020.08.10.245191 — genetics — Posted on 2020-08-12
2860 Wnt/PCP-primed intestinal stem cells directly differentiate into enteroendocrine or Paneth cells
Boettcher, A.; Buettner, M.; Tritschler, S.; Sterr, M.; Aliluev, A.; Oppenlaender, L.; Burtscher, I.; Sass, S.; Irmler, M.; Beckers, J.; Ziegenhain, C.; Enard, W.; Schamberger, A. C.; Verhamme, F. M.; Eickelberg, O.; Theis, F. J.; Lickert, H.
10.1101/2020.08.12.247585 — developmental biology — Posted on 2020-08-12
2862 Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues
DeVilbiss, A. W.; Zhao, Z.; Martin-Sandoval, M. S.; Ubellacker, J. M.; Tasdogan, A.; Agathocleous, M.; Mathews, T. P.; Morrison, S. J.
10.1101/2020.08.11.246900 — cell biology — Posted on 2020-08-12
2864 Chronic Exposure to Palmitic Acid Downregulates AKT in Beta-Cells through Activation of mTOR
Aggarwal, R.; Peng, Z.; Zeng, N.; Silva, J.; He, L.; Chen, J.; Debebe, A.; Stiles, E.; Chen, C.-Y.; Stiles, B. L.
10.1101/2020.08.11.247452 — cell biology — Posted on 2020-08-12
2866 Antagonism of STAT3 signalling by Ebola virus
Harrison, A. R.; Dearnley, M.; Todd, S.; Green, D.; Marsh, G. A.; Moseley, G. W.
10.1101/2020.08.10.245464 — microbiology — Posted on 2020-08-12
2869 Bayesian model selection favors parametric over categorical fMRI subsequent memory models in young and older adults
Soch, J.; Richter, A.; Schuetze, H.; Kizilirmak, J. M.; Assmann, A.; Knopf, L.; Raschick, M.; Schult, A.; Maass, A.; Ziegler, G.; Richardson-Klavehn, A.; Duezel, E.; Schott, B. H.
10.1101/2020.07.27.220871 — neuroscience — Posted on 2020-08-12
2870 A general theory of coherence between brain areas
Schneider, M.; Dann, B.; Sheshadri, S.; Scherberger, H.; Vinck, M.
10.1101/2020.06.17.156190 — neuroscience — Posted on 2020-08-12
2871 Autophagy is required for lipid homeostasis during dark-induced senescence in Arabidopsis
Barros, J. A.; Magen, S.; Lapidot-Cohen, T.; Rosental, L.; Brotman, Y.; Araujo, W. L.; Avin-Wittenberg, T.
10.1101/2020.08.10.245092 — plant biology — Posted on 2020-08-12
2873 Light into the darkness: Unifying the known and unknown coding sequence space in microbiome analyses
Vanni, C.; Schechter, M. S.; Acinas, S. G.; Barberan, A.; Buttigieg, P. L.; Casamayor, E. O.; Delmont, T. O.; Duarte, C. M.; Eren, A. M.; Finn, R.; Kottmann, R.; Mitchell, A.; Sanchez, P.; Siren, K.; Steinegger, M.; Glöckner, F. O.; Fernandez-Guerra, A.
10.1101/2020.06.30.180448 — microbiology — Posted on 2020-08-12
2874 High-speed, long-term, 4D in vivo lifetime imaging in intact and injured zebrafish and mouse brains by instant FLIM
Zhang, Y.; Guldner, I. H.; Nichols, E. L.; Benirschke, D.; Smith, C. J.; Zhang, S.; Howard, S. S.
10.1101/2020.02.05.936039 — neuroscience — Posted on 2020-08-12
2876 SpikeInterface, a unified framework for spike sorting
Buccino, A. P.; Hurwitz, C. L.; Garcia, S.; Magland, J.; Siegle, J. H.; Hurwitz, R.; Hennig, M. H.
10.1101/796599 — neuroscience — Posted on 2020-08-12
2878 Gamma-protocadherin localization at the synapse corresponds to parameters of synaptic maturation
LaMassa, N.; Sverdlov, H.; Mambetalieva, A.; Shapiro, S.; Bucaro, M.; Fernandez-Monreal, M.; Phillips, G. R.
10.1101/760041 — neuroscience — Posted on 2020-08-12
2881 Dense, high-resolution mapping of cells and tissues from pathology images for the interpretable prediction of molecular phenotypes in cancer
Diao, J. A.; Chui, W. F.; Wang, J. K.; Mitchell, R. N.; Rao, S. K.; Resnick, M. B.; Lahiri, A.; Maheshwari, C.; Glass, B.; Mountain, V.; Kerner, J. K.; Montalto, M. C.; Khosla, A.; Wapinski, I. N.; Beck, A. H.; Taylor-Weiner, A.; Elliott, H.
10.1101/2020.08.02.233197 — bioinformatics — Posted on 2020-08-12
2882 Model-based prediction of bacterial population dynamics in gastrointestinal infection
Geissert, J.; Bohn, E.; Mostolizadeh, R.; Draeger, A.; Autenrieth, I.; Beier, S.; Deusch, O.; Eichner, M.; Schuetz, M.
10.1101/2020.08.11.244202 — microbiology — Posted on 2020-08-12
2883 Staphylococcal DNA repair is required for infection
Ha, K. P.; Clarke, R. S.; Kim, G.-L.; Brittan, J. L.; Rowley, J. E.; Mavridou, D.; Parker, D.; Clarke, T. B.; Nobbs, A. H.; Edwards, A. M.
10.1101/2020.02.23.961458 — microbiology — Posted on 2020-08-12
2885 Antigen-Specific T Cell Recall Assay To Screen Drugs For Off-Target Effects
Kleiman, E.; Sierra, G.; Magcase, D.; George, M. V.; Daftarian, P. M.
10.1101/2020.08.10.241869 — immunology — Posted on 2020-08-12
2887 Common synaptic phenotypes arising from diverse mutations in the human NMDA receptor subunit GluN2A
Elmasri, M.; Hunter, D.; Winchester, G.; Aziz, W.; Bates, E.; Moolenaar Van Der Does, D.; Karachaliou, E.; Sakimura, K.; Penn, A. C.
10.1101/2020.08.06.240010 — neuroscience — Posted on 2020-08-12
2889 SCAPP: An algorithm for improved plasmid assembly in metagenomes
Pellow, D.; Zorea, A.; Probst, M.; Furman, O.; Segal, A.; Mizrahi, I.; Shamir, R.
10.1101/2020.01.12.903252 — bioinformatics — Posted on 2020-08-12
2892 Worldwide tracing of mutations and the evolutionary dynamics of SARS-CoV-2
Zhou, Z.-Y.; Liu, H.; Zhang, Y.-D.; Wu, Y.-Q.; Peng, M.-S.; Li, A.; Irwin, D. M.; Li, H.; Lu, J.; Bao, Y.; Lu, X.; Liu, D.; Zhang, Y.-P.
10.1101/2020.08.07.242263 — microbiology — Posted on 2020-08-12
2893 Heat-treated virus inactivation rate depends strongly on treatment procedure
Gamble, A.; Fischer, R. J.; Morris, D. H.; Yinda, K. C.; Munster, V. J.; Lloyd-Smith, J. O.
10.1101/2020.08.10.242206 — microbiology — Posted on 2020-08-12
2894 Microbial grazers may aid in controlling infections caused by aquatic zoosporic fungi
Farthing, H. N.; Jiang, J.; Henwood, A. J.; Fenton, A.; Garner, T.; Daversa, D. R.; Fisher, M. C.; Montagnes, D. J. S.
10.1101/2020.02.03.931857 — microbiology — Posted on 2020-08-12
2895 Human Embryonic Stem Cell-derived Lung Organoids: a Model for SARS-CoV-2 Infection and Drug Test
Pei, R.; Feng, J.; Zhang, Y.; Sun, H.; Li, L.; Yang, X.; He, J.; Xiao, S.; Xiong, J.; Lin, Y.; Wen, K.; Zhou, H.; Chen, J.; Rong, Z.; Chen, X.
10.1101/2020.08.10.244350 — microbiology — Posted on 2020-08-12
2900 Connectome Harmonic Decomposition of Human Brain Dynamics Reveals a Landscape of Consciousness
Luppi, A. I.; Vohryzek, J.; Kringelbach, M. L.; Mediano, P. A. M.; Craig, M. M.; Adapa, R.; Carhart-Harris, R. L.; Roseman, L.; Pappas, I.; Finoia, P.; Williams, G. B.; Allanson, J.; Pickard, J. D.; Menon, D. K.; Atasoy, S.; Stamatakis, E. A.
10.1101/2020.08.10.244459 — neuroscience — Posted on 2020-08-12
2902 Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression
Mangiola, S.; McCoy, P.; Modrak, M.; Guimaraes, F. S. F.; Blashki, D.; Stuchbery, R.; Keam, S. P.; Kerger, M.; Chow, K.; Nasa, C.; Le Page, M.; Lister, N.; Monard, S.; Peters, J.; Dundee, P.; Williams, S. G.; Costello, A. J.; Neeson, P. J.; Pal, B.; Huntington, N. D.; Corcoran, N.; Papenfuss, A. T.; Hovens, C. M.
10.1101/2020.03.16.993162 — cancer biology — Posted on 2020-08-12
2903 The role of toxin:antitoxin systems and insertion sequences in the loss of virulence in Shigella sonnei
Martyn, J. E.; Pilla, G.; Hollingshead, S.; Lobanovska, M.; Winther, K. S.; Lea, S.; McVicker, G.; Tang, C. M.
10.1101/2020.08.10.243006 — microbiology — Posted on 2020-08-12
2904 Feature selection and causal analysis for microbiome studies in the presence of confounding using standardization
Goren, E.; Wang, C.; He, Z.; Sheflin, A. M.; Chiniquy, D.; Prenni, J. E.; Tringe, S.; Schachtman, D. P.; Liu, P.
10.1101/2020.08.09.243188 — microbiology — Posted on 2020-08-12
2909 A non-invasive method to generate induced pluripotent stem cells from primate urine
Geuder, J.; Ohnuki, M.; Wange, L. E.; Janjic, A.; Bagnoli, J.; Müller, S.; Kaul, A.; Enard, W.
10.1101/2020.08.12.247619 — cell biology — Posted on 2020-08-12
2910 Targeting KRAS-mutant stomach/colorectal tumours by disrupting the ERK2-p53 complex
Lang, J.-Y.; Wang, X.; Xie, Q.; Ji, Y.; Shen, J.; Wang, C.; Jiang, X.; Chen, Z.; Zhang, Y.; Kong, X.; Ding, J.
10.1101/2020.08.12.247460 — cancer biology — Posted on 2020-08-12
2911 EGFR transactivates RON to drive oncogenic crosstalk
Franco Nitta, C.; Green, E. W.; Jhamba, E. D.; Keth, J. M.; Ortiz-Caraveo, I.; Grattan, R. M.; Schodt, D. J.; Gibson, A. C.; Rajput, A.; Lidke, K. A.; Steinkamp, M. P.; Wilson, B. S.; Lidke, D. S.
10.1101/2020.08.11.246785 — cancer biology — Posted on 2020-08-12
2914 The RAD51 recombinase protects mitotic chromatin in human cells
Wassing, I. E.; Saayman, X.; Rampazzo, L.; Ralf, C.; Bassett, A.; Esashi, F.
10.1101/2020.08.11.246231 — molecular biology — Posted on 2020-08-11
2915 ChIP-seq of plasma cell-free nucleosomes identifies cell-of-origin gene expression programs
Sadeh, R.; Sharkia, I.; Fialkoff, G.; Rahat, A.; Gutin, J.; Chappleboim, A.; Nitzan, M.; Fox-Fisher, I.; Neiman, D.; Meler, G.; Kamari, Z.; Yaish, D.; Peretz, T.; Hubert, A.; Cohen, J. E.; Azzam, S.; Temper, M.; Grinshpun, A.; Maoz, M.; Abu-Gazala, S.; Ben Ya'acov, A.; Shteyer, E.; Safadi, R.; Kaplan, T.; Shemer, R.; Planer, D.; Galun, E.; Glaser, B.; Zik, A.; Dor, Y.; Friedman, N.
10.1101/638643 — molecular biology — Posted on 2020-08-11
2916 Structural studies of Cardiovirus 2A protein reveal the molecular basis for RNA recognition and translational control
Hill, C. H.; Napthine, S.; Pekarek, L.; Kibe, A.; Firth, A. E.; Graham, S. C.; Caliskan, N.; Brierley, I.
10.1101/2020.08.11.245035 — molecular biology — Posted on 2020-08-11
2917 Small molecule cognitive enhancer reverses age-related memory decline in mice.
Krukowski, K.; Nolan, A.; Frias, E. S.; Boone, M.; Ureta, G.; Grue, K.; Paladini, M.-S.; Elizarraras, E.; Delgado, L.; Bernales, S.; Walter, P.; Rosi, S.
10.1101/2020.04.13.039677 — neuroscience — Posted on 2020-08-11
2919 Structural and molecular basis for protein-stimulated ribosomal frameshifting in Theiler's murine encephalomyelitis virus
Hill, C. H.; Cook, G.; Napthine, S.; Kibe, A.; Brown, K.; Caliskan, N.; Firth, A. E.; Graham, S. C.; Brierley, I.
10.1101/2020.08.11.245068 — molecular biology — Posted on 2020-08-11
2920 SARM1 depletion rescues NMNAT1 dependent photoreceptor cell death and retinal degeneration.
Sasaki, Y.; Kakita, H.; Kubota, S.; Sene, A.; Lee, T. J.; Ban, N.; Dong, Z.; Lin, J. B.; Boye, S. L.; DiAntonio, A.; Boye, S. E.; Apte, R. S.; Milbrandt, J.
10.1101/2020.04.30.069385 — neuroscience — Posted on 2020-08-11
2921 Peptide YY: a novel Paneth cell antimicrobial peptide that maintains fungal commensalism
Pierre, J. F.; La Torre, D.; Sidebottom, A.; Kambal, A.; Zhu, X.; Tao, Y.; Cham, C. M.; Wang, L.; Harris, K. G.; Zaborina, O.; Alverdy, J. C.; Herzog, H.; Witchley, J.; Noble, S. M.; Leone, V.; Chang, E. B.
10.1101/2020.05.15.096875 — molecular biology — Posted on 2020-08-11
2922 Alcohol boosts pheromone production in male flies and makes them sexier
Keesey, I. W.; Doll, G.; Das Chakraborty, S.; Baschwitz, A.; Lemoine, M.; Kaltenpoth, M.; Svatos, A.; Sachse, S.; Knaden, M.; Hansson, B. S.
10.1101/2020.08.09.242784 — neuroscience — Posted on 2020-08-11
2923 A DNA-origami nuclear pore mimic reveals nuclear entry mechanisms of HIV-1 capsid
Shen, Q.; Xu, C.; Jang, S.; Xiong, Q.; Devarkar, S.; Tian, T.; Bedwell, G.; Tripler, T.; Hu, Y.; Yuan, S.; Temple, J.; Shi, J.; Aiken, C.; Engelman, A.; Perilla, J. R.; Lusk, C. P.; Lin, C.; Xiong, Y.
10.1101/2020.08.10.245522 — microbiology — Posted on 2020-08-11
2927 Pleiotropic effect of Lactoferrin in the prevention and treatment of COVID-19 infection: in vivo, in silico and in vitro preliminary evidences
Campione, E.; Lanna, C.; Cosio, T.; Rosa, L.; Conte, M. P.; Iacovelli, F.; Romeo, A.; Falconi, M.; Del Vecchio, C.; Franchin, E.; Lia, M. S.; Minieri, M.; Chiaramonte, C.; Ciotti, M.; Nuccetelli, M.; Terrinoni, A.; Iannuzzi, I.; Coppeda, L.; Magrini, A.; Moricca, N.; Sabatini, S.; Rosapepe, F.; Bartoletti, P. L.; Bernardini, S.; Andreoni, M.; Valenti, P.; Bianchi, L.
10.1101/2020.08.11.244996 — microbiology — Posted on 2020-08-11
2930 Functional Organization of Midget and Parasol Ganglion Cells in the Human Retina
Kling, A.; Gogliettino, A. R.; Shah, N. P.; Wu, E. G.; Brackbill, N.; Sher, A.; Litke, A.; Silva, R. A.; Chichilnisky, E. J.
10.1101/2020.08.07.240762 — neuroscience — Posted on 2020-08-11
2933 K18-hACE2 mice develop respiratory disease resembling severe COVID-19
Yinda, C. K.; Port, J. R.; Bushmaker, T. J.; Offei Owusu, I.; Avanzato, V. A.; Fischer, R. J.; Schulz, J. E.; Holbrook, M. G.; Hebner, M. J.; Rosenke, R.; Thomas, T.; Marzi, A.; Best, S. M.; de Wit, E.; Shaia, C.; van Doremalen, N.; Munster, V.
10.1101/2020.08.11.246314 — microbiology — Posted on 2020-08-11
2936 Sonlicromanol improves neuronal network dysfunction and transcriptome changes linked to m.3243A > G heteroplasmy in iPSC-derived neurons
Klein Gunnewiek, T. M.; Verboven, A. H. A.; Hogeweg, M.; Schoenmaker, C.; Renkema, H.; Beyrath, J.; Smeitink, J.; De Vries, B. B. A.; Kozicz, T.; 't Hoen, P. A. C.; Nadif Kasri, N. M.
10.1101/2020.08.11.246140 — neuroscience — Posted on 2020-08-12
2937 Model-based prediction of bacterial population dynamics in gastrointestinal infection
Geissert, J.; Bohn, E.; Mostolizadeh, R.; Draeger, A.; Autenrieth, I.; Beier, S.; Deusch, O.; Eichner, M.; Schuetz, M.
10.1101/2020.08.11.244202 — microbiology — Posted on 2020-08-11
2938 DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction
Lau, O. C. E.; Damiani, D.; Jossin, Y.; Chehade, G.; Schakman, O.; Tajeddine, N.; Gailly, P.; Tissir, F.
10.1101/2020.08.11.245829 — neuroscience — Posted on 2020-08-12
2941 Co-evolutionary signals from Burkholderia pseudomallei population genomics highlight its survival strategy in a hostile environment
Chewapreecha, C.; Pensar, J.; Chattagul, S.; Pesonen, M.; Sangphukieo, A.; Boonklang, P.; Potisap, C.; Koosakulnirand, S.; Feil, E. J.; Dunachie, S.; Chantratita, N.; Limmathurotsakul, D.; Peacock, S. J.; Day, N. P. J.; Parkhill, J.; Thomson, N. R.; Sermswan, R. W.; Corander, J.
10.1101/2020.08.11.245894 — microbiology — Posted on 2020-08-11
2942 The McdAB system positions α-carboxysomes in proteobacteria
MacCready, J. S.; Tran, L.; Basalla, J. L.; Hakim, P.; Vecchiarelli, A. G.
10.1101/2020.08.11.246918 — microbiology — Posted on 2020-08-11
2943 The phase of Theta oscillations modulates successful memory formation at encoding
Cruzat, J.; Torralba, M.; Ruzzoli, M.; Fernandez, A.; Deco, G.; Soto-Faraco, S.
10.1101/2020.08.11.246421 — neuroscience — Posted on 2020-08-12
2944 Redefining De Novo Gammaherpesvirus Infection Through High-Dimensional, Single-Cell Analysis of Virus and Host
Berger, J. N.; Sanford, B.; Kimball, A. K.; Oko, L. M.; Kaspar, R. E.; Niemeyer, B. F.; Jones, K. L.; Clambey, E. T.; van Dyk, L. F.
10.1101/2020.08.11.203117 — microbiology — Posted on 2020-08-11
2948 Purinergic signaling controls spontaneous activityin the auditory system throughout early development
Babola, T. A.; Li, S.; Wang, Z.; Kersbergen, C. J.; Elgoyhen, A. B.; Coate, T. M.; Bergles, D. E.
10.1101/2020.08.11.246306 — neuroscience — Posted on 2020-08-12
2950 Light into the darkness: Unifying the known and unknown coding sequence space in microbiome analyses
Vanni, C.; Schechter, M. S.; Acinas, S.; Barberan, A.; Buttigieg, P. L.; Casamayor, E. O.; Delmont, T. O.; Duarte, C. M.; Eren, A. M.; Finn, R. D.; Kottmann, R.; Mitchell, A.; Sanchez, P.; Siren, K.; Steinegger, M.; Glöckner, F. O.; Fernandez-Guerra, A.
10.1101/2020.06.30.180448 — microbiology — Posted on 2020-08-11
2952 Spinal dI2 interneurons regulate the stability of bipedal stepping
Haimson, B.; Hadas, Y.; Kania, A.; Daley, M.; Cinnamon, Y.; Lev-Tov, A.; Klar, A.
10.1101/2020.01.07.898072 — neuroscience — Posted on 2020-08-12
2953 Dengue arbovirus affecting temperate Argentina province for more than a decade 2009-2020.
LOPEZ, M. S.; JORDAN, D. I.; BLATTER, E.; WALKER, E.; GOMEZ, A. A.; MULLER, G. V.; MENDICINO, D.; ESTALLO, E. L.
10.1101/2020.08.11.246272 — microbiology — Posted on 2020-08-11
2956 Up-Regulation of αCaMKII Impairs Cued Fear Extinction and NMDAR-Dependent LTD in the Lateral Amygdala
Cao, X.; An, S.; Wang, J.; Zhang, X.; Duan, Y.; Lv, J.; Wang, D.; Zhang, H.; Richter-Levin, G.
10.1101/2020.08.11.247270 — neuroscience — Posted on 2020-08-12
2958 Nitric oxide-inducible Fe-S cluster biogenesis enables Mycobacterium tuberculosis to persist in mice
Anand, K.; Tripathi, A.; Shukla, K.; Malhotra, N.; Jamithireddy, A.; Jha, R. K.; Chaudhury, S. N.; Rajmani, R. S.; Ramesh, A.; Nagaraja, V.; Gopal, B.; Nagaraju, G.; Seshasayee, A. S. N.; Singh, A.
10.1101/2020.08.10.245365 — microbiology — Posted on 2020-08-11
2961 Nitric oxide-inducible Fe-S cluster biogenesis enables Mycobacterium tuberculosis to persist in mice
Anand, K.; Tripathi, A.; Shukla, K.; Malhotra, N.; Jamithireddy, A.; Jha, R. K.; Chaudhury, S. N.; Rajmani, R. S.; Ramesh, A.; Nagaraja, V.; Gopal, B.; Nagaraju, G.; Seshayee, A. S. N.; Singh, A.
10.1101/2020.08.10.245365 — microbiology — Posted on 2020-08-12
2963 Genotyping of Russian isolates of fungal pathogen Trichophyton rubrum, based on simple sequence repeat and single nucleotide polymorphism
Pchelin, I. M.; Mochalov, Y. V.; Azarov, D. V.; Romanyuk, S. A.; Chilina, G. A.; Vybornova, I. V.; Bogdanova, T. V.; Zlatogursky, V. V.; Apalko, S. V.; Vasilyeva, N. V.; Taraskina, A. E.
10.1101/2020.03.06.980839 — microbiology — Posted on 2020-08-12
2964 Evaluation of Fecal Immunoassays for Canine Echinococcus Infection in China
WANG, L.; Wang, Q.; Cai, H.; Wang, H.; Huang, Y.; Feng, Y.; Bai, X.; Qin, M.; Manguin, S.; Gavotte, L.; Wu, W.; Frutos, R.
10.1101/2020.08.11.246009 — zoology — Posted on 2020-08-11
2965 How widespread was the Tapanuli orangutan and what led to its decline?
Meijaard, E.; Ni'matullah, S.; Dennis, R.; Hadisiswoyo, P.; Sherman, J.; O., O.; Wich, S. A.
10.1101/2020.08.11.246058 — zoology — Posted on 2020-08-11
2968 dCas9 regulator to neutralize competition in CRISPRi circuits
Huang, H.-H.; Bellato, M.; Qian, Y.; Cardenas, P.; Pasotti, L.; Magni, P.; Del Vecchio, D.
10.1101/2020.08.11.246561 — synthetic biology — Posted on 2020-08-11
2969 Systematic Engineering of Artificial Metalloenzymes for New-to-Nature Reactions
Vornholt, T.; Christoffel, F.; Pellizzoni, M.; Panke, S.; Ward, T. R.; Jeschek, M.
10.1101/2020.07.15.204206 — synthetic biology — Posted on 2020-08-11
2970 Does retraction after misconduct have an impact on citations? A pre-post study.
Candal-Pedreira, C.; Ruano-Ravina, A.; Fernandez, E.; Ramos, J.; Campos-Varela, I.; Perez-Rios, M.
10.1101/2020.08.11.246637 — scientific communication and education — Posted on 2020-08-11
2971 Tomato spotted wilt virus benefits its thrips vector by modulating metabolic and plant defense pathways in tomato
Nachappa, P.; Challacombe, J. F.; Margolies, D. C.; Nechols, J. R.; Whitfield, A. E.; Rotenberg, D.
10.1101/2020.08.10.244665 — plant biology — Posted on 2020-08-11
2972 Arabidopsis thaliana Zn2+-efflux ATPases HMA2 and HMA4 are required for resistance to the necrotrophic fungus Plectosphaerella cucumerina BMM
Escudero, V.; Castro-Leon, A.; Ferreira Sanchez, D.; Abreu, I.; Bernal, M.; Kramer, U.; Grolimund, D.; Gonzalez-Guerrero, M.; Jorda, L.
10.1101/2020.08.10.243014 — plant biology — Posted on 2020-08-11
2973 The conserved plant PM19 protein functions as an osmosensor and regulator of germination
Alexander, R. D.; Castillejo-Pons, P.; Alsaif, O.; Stahl, Y.; Seale, M.; Morris, P. C.
10.1101/2020.08.10.244889 — plant biology — Posted on 2020-08-11
2974 Structural basis for VIPP1 oligomerization and maintenance of thylakoid membrane integrity
Kumar Gupta, T.; Klumpe, S.; Gries, K.; Heinz, S.; Wietrzynski, W.; Ohnishi, N.; Niemeyer, J.; Schaffer, M.; Rast, A.; Strauss, M.; Plitzko, J. M.; Baumeister, W.; Rudack, T.; Sakamoto, W.; Nickelsen, J.; Schuller, J. M.; Schroda, M.; Engel, B. D.
10.1101/2020.08.11.243204 — plant biology — Posted on 2020-08-11
2977 Effect of cutting depth during sugarcane harvest on root characteristics and yield
Zhang, Y.-b.; Yang, S.-l.; Deng, J.; Li, R.-d.; Fan, X.; Dao, J.-m.; Quan, Y.-j.; Hussain Bukhari, S. A.; Zeng, Z.-h.
10.1101/2020.08.11.246033 — plant biology — Posted on 2020-08-11
2979 At-level allodynia after mid-thoracic contusion in the rat
Blumenthal, G. H.; Nandakumar, B.; Schnider, A. K.; Detloff, M. R.; Ricard, J.; Bethea, J. R.; Moxon, K. A.
10.1101/2020.08.10.240499 — physiology — Posted on 2020-08-11
2981 AT-527 is a potent in vitro replication inhibitor of SARS-CoV-2, the virus responsible for the COVID-19 pandemic
Good, S. S.; Westover, J.; Jung, K.-H.; La Colla, P.; Collu, G.; Moussa, A.; Canard, B.; Sommadossi, J.-P.
10.1101/2020.08.11.242834 — pharmacology and toxicology — Posted on 2020-08-11
2982 Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening
Zhu, W.; Xu, M.; Chen, C. Z.; Guo, H.; Shen, M.; Hu, X.; Shinn, P.; Klumpp-Thomas, C.; Michael, S. G.; Zheng, W.
10.1101/2020.07.17.207019 — pharmacology and toxicology — Posted on 2020-08-11
2983 AT-527 is a potent in vitro replication inhibitor of SARS-CoV-2, the virus responsible for the COVID-19 pandemic
Good, S. S.; Westover, J.; Jung, K. H.; La Colla, P.; Collu, G.; Moussa, A.; Canard, B.; Sommadossi, J.-P.
10.1101/2020.08.11.242834 — pharmacology and toxicology — Posted on 2020-08-11
2984 Acute Respiratory Distress and Cytokine Storm in Aged, SARS-CoV-2 Infected African Green Monkeys, but not in Rhesus Macaques
Blair, R. V.; Vaccari, M.; Doyle-Meyers, L. A.; Roy, C. J.; Russell-Lodrigue, K.; Fahlberg, M.; Monjure, C. J.; Beddingfield, B.; Plante, K. S.; Plante, J. A.; Weaver, S. C.; Qin, X.; Midkiff, C. C.; Lehmicke, G.; Golden, N.; Threeton, B.; Penney, T.; Allers, C.; Barnes, M. B.; Pattison, M.; Datta, P. K.; Maness, N. J.; Birnbaum, A.; Bohm, R. P.; Rappaport, J.
10.1101/2020.06.18.157933 — pathology — Posted on 2020-08-11
2985 A new rat model of creatine transporter deficiency reveals behavioral disorder and altered brain metabolism
Duran-Trio, L.; Fernandes-Pires, G.; Simicic, D.; Grosse, J.; Roux, C.; Binz, P.-A.; Sandi, C.; Cudalbu, C.; Braissant, O.
10.1101/2020.08.11.246330 — pathology — Posted on 2020-08-12
2986 Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function
Palanikumar, L.; Karpauskaite, L.; Hassan, S.; Alam, M.; Al-Sayegh, M.; Chehade, I.; Maity, D.; Ali, L.; Falls, Z.; Samudrala, R.; Kalmouni, M.; Hunashal, Y.; Ahmed, J.; Karapetyan, S.; Pasricha, R.; Esposito, G.; Afzal, A. J.; Hamilton, A. D.; Kumar, S.; Magzoub, M.
10.1101/2020.08.10.243154 — cancer biology — Posted on 2020-08-11
2987 C/EBPB-dependent Adaptation to Palmitic Acid Promotes Stemness in Hormone Receptor Negative Breast Cancer
Liu, X.; Rulina, A.; Choi, M. H.; Pedersen, L.; Lepland, J.; Madeleine, N.; Peters, S.; Wogsland, C. E.; Grondal, S. M.; Lorens, J.; Goodarzi, H.; Molven, A.; Lonning, P. E.; Knappskog, S.; Halberg, N.
10.1101/2020.08.11.244509 — cancer biology — Posted on 2020-08-11
2988 Glioblastoma utilizes fatty acids and ketone bodies for growth allowing progression during ketogenic diet therapy
Sperry, J.; Condro, M. C.; Guo, L.; Kim, K. K. O.; Vanderveer-Harris, N.; Braas, D.; Pope, W. B.; Divakurani, A. S.; Lai, A.; Christofk, H.; Le Belle, J. E.; Kornblum, H. I.
10.1101/659474 — cancer biology — Posted on 2020-08-11
2989 Chemotactic Migration of Bacteria in Porous Media
Bhattacharjee, T.; Amchin, D. B.; Ott, J. A.; Kratz, F.; Datta, S. S.
10.1101/2020.08.10.244731 — biophysics — Posted on 2020-08-11
2996 Symmetry breaking and de-novo axis establishment in hydra: microtubules as a pivotal element
Sander, H.; Pasula, A.; Sander, M.; Giri, V.; Terriac, E.; Lautenschlaeger, F.; Ott, A.
10.1101/2020.01.14.906115 — biophysics — Posted on 2020-08-11
3001 FAIRSCAPE: A Framework for FAIR and Reproducible Biomedical Analytics
Levinson, M. A.; Niestroy, J.; Al Manir, S.; Fairchild, K. D.; Lake, D. E.; Moorman, J. R.; Clark, T.
10.1101/2020.08.10.244947 — bioinformatics — Posted on 2020-08-11
3003 ZeroCostDL4Mic: an open platform to use Deep-Learning in Microscopy
Chamier, L. v.; Laine, R. F.; Jukkala, J.; Spahn, C.; Krentzel, D.; Nehme, E.; Lerche, M.; Hernandez-perez, S.; Mattila, P.; Karinou, E.; Holden, S.; Can Solak, A.; Krull, A.; Buchholz, T.-O.; Jones, M. L.; Royer, L. A.; Leterrier, C.; Shechtman, Y.; Jug, F.; Heilemann, M.; Jacquemet, G.; Henriques, R.
10.1101/2020.03.20.000133 — bioinformatics — Posted on 2020-08-11
3010 Characterizing and controlling nanoscale self-assembly of suckerin-12
Hershewe, J. M.; Wiseman, W. D.; Kath, J. E.; Buck, C. C.; Gupta, M. K.; Dennis, P. B.; Naik, R. R.; Jewett, M. C.
10.1101/2020.08.10.244673 — bioengineering — Posted on 2020-08-11
3011 Percolation of Microparticle Matrix Promotes Cell Migration and Integration while Supporting Native Tissue Architecture
Barthold, J.; St. Martin, B.; Lalitha Sridhar, S.; Vernerey, F.; Schneider, S.; Wacquez, A.; Ferguson, V.; Calve, S.; Neu, C.
10.1101/2020.08.10.245589 — bioengineering — Posted on 2020-08-11
3015 Cryo-EM Structures of the SARS-CoV-2 Endoribonuclease Nsp15
Pillon, M. C.; Frazier, M. N.; Dillard, L.; Williams, J. G.; Kocaman, S.; Krahn, J. M.; Perera, L.; Hayne, C. K.; Gordon, J.; Stewart, Z. D.; Sobhany, M.; Deterding, L. J.; Hsu, A. L.; Dandey, V. P.; Borgnia, M. J.; Stanley, R. E.
10.1101/2020.08.11.244863 — biochemistry — Posted on 2020-08-11
3016 Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons
Ipsaro, J. J.; O'Brien, P. A.; Bhattacharya, S.; Palmer, A. G.; Joshua-Tor, L.
10.1101/2020.08.11.246769 — biochemistry — Posted on 2020-08-11
3017 Temporal modulation of the NF-κB RelA network in response to different types of DNA damage
Campbell, A.; Ferraz Franco, C.; Su, L.-I.; Perkins, S.; Jones, A. R.; Brownridge, P. J.; Perkins, N. D.; Eyers, C. E.
10.1101/2020.08.11.246504 — biochemistry — Posted on 2020-08-11
3018 Genetic-substructure and complex demographic history of South African Bantu speakers
Sengupta, D.; Choudhury, A.; Fortes-Lima, C.; Aron, S.; Whitelaw, G.; Bostoen, K.; Gunnink, H.; Chousou-Polydouri, N.; Delius, P.; Tollman, S.; Casas, F. G.-O.; Norris, S.; Mashinya, F.; Alberts, M.; Hazelhurst, S.; Schlebusch, C. M.; Ramsay, M.
10.1101/2020.08.11.243840 — genomics — Posted on 2020-08-11
3019 ViruSurf: an integrated database to investigate viral sequences
Canakoglu, A.; Pinoli, P.; Bernasconi, A.; Alfonsi, T.; Melidis, D. P.; Ceri, S.
10.1101/2020.08.10.244624 — genomics — Posted on 2020-08-11
3027 Variants in RABL2A causing male infertility and ciliopathy
Ding, X.; Fragoza, R.; Singh, P.; Zhang, S.; Yu, H.; Schimenti, J. C.
10.1101/2020.08.11.246611 — genetics — Posted on 2020-08-11
3030 Massively parallel functional testing of MSH2 missense variants conferring Lynch Syndrome risk
Jia, X.; Burugula, B. B.; Chen, V.; Lemons, R. M.; Jayakody, S.; Maksutova, M.; Kitzman, J. O.
10.1101/2020.06.03.133017 — genetics — Posted on 2020-08-11
3034 Human vulnerability to cancer malignancy is enhanced by evolution of higher mesenchymal CD44 expression compared to other mammals
Ma, X.; Dighe, A.; Maziarz, J.; Neumann, E.; Erkenbrack, E.; Hei, Y.-Y.; Liu, Y.; Suhail, Y.; Kshitiz, K.; Pak, I.; Levchenko, A.; Wagner, G.
10.1101/2020.08.03.234617 — evolutionary biology — Posted on 2020-08-11
3035 Genetic population structure constrains local adaptation in sticklebacks
Kemppainen, P. M.; Li, Z.; Rastas, P.; Loytynoja, A.; Fang, B.; Guo, B.; Shikano, T.; Yang, J.; Merila, J.
10.1101/2020.01.17.908970 — evolutionary biology — Posted on 2020-08-11
3037 Facultative chemosynthesis in a deep-sea anemone from hydrothermal vents in the Pescadero Basin, Gulf of California
Goffredi, S. K.; Motooka, C.; Fike, D. A.; Gusmao, L. C.; Tilic, E.; Rouse, G. W.; Rodriguez, E.
10.1101/2020.08.10.245456 — ecology — Posted on 2020-08-11
3039 Moose or spruce: A systems analysis model for managing conflicts between moose and forestry in Sweden
Franklin, O.; Krasovskiy, A.; Kraxner, F.; Platov, A.; Shchepashchenko, D.; Leduc, S.; Mattsson, B.
10.1101/2020.08.11.241372 — ecology — Posted on 2020-08-11
3040 Induced drought strongly affects richness and composition of ground-dwelling ants in the eastern Amazon
Almeida, R. P. S.; Silva, R. R.; Costa, A. C. L. d.; Ferreira, L. V.; Meir, P.; Ellison, A. M.
10.1101/2020.08.10.242180 — ecology — Posted on 2020-08-11
3041 Diet-induced changes to host gut microbiota are linked to foraging innovation in a wild bird.
Davidson, G.; Wiley, N.; Cooke, A. C.; Johnson, C. N.; Fouhy, F.; Reichert, M. S.; de la Hera, I.; Crane, J. M. S.; Kulahci, I. G.; Ross, R. P.; Stanton, C.; Quinn, J. L.
10.1101/827741 — ecology — Posted on 2020-08-11
3042 Shifting Baselines: Physiological legacies contribute to the response of reef coral to frequent heat waves
Wall, C. B.; Ricci, C.; Wen, A.; Ledbetter, B.; Klinger, D.; Mydlarz, L.; Gates, R. D.; Putnam, H.
10.1101/2020.04.23.056457 — ecology — Posted on 2020-08-11
3049 Complex plant metabolomes guide fitness-relevant foraging decisions of a specialist herbivore
Machado, R. A. R.; Theepan, V.; Robert, C. A. M.; Zuest, T.; Hu, L.; Su, Q.; Schimmel, B. C. J.; Erb, M.
10.1101/2020.07.13.200618 — animal behavior and cognition — Posted on 2020-08-11
3051 Differential effects of voclosporin and tacrolimus on insulin secretion from human islets
Kolic, J.; Beet, L.; Overby, P.; Cen, H. H.; Panzhinskiy, E.; Ure, D. R.; Cross, J. L.; Huizinga, R. B.; Johnson, J. D.
10.1101/2020.04.30.071324 — cell biology — Posted on 2020-08-11
3053 Direct uptake mechanism in lysosome required for neuromuscular homeostasis
Fujiwara, Y.; Contu, V. R.; Kabuta, C.; Ogawa, M.; Fujita, H.; Kikuchi, H.; Sakai, R.; Hase, K.; Mari Suzuki, M.; Koyama-Honda, I.; Inoue, M.; Oya, Y.; U. Inoue, Y.; Inoue, T.; Takahashi, R.; Nishino, I.; Wada, K.; Noguchi, S.; Kabuta, T.
10.1101/2020.08.11.245688 — cell biology — Posted on 2020-08-11
3054 The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function
Oftedal, B. E.; Maio, S.; Handel, A.; White, M. P.; Howie, D.; Davis, S.; Prevot, N.; Rota, I. A.; Deadman, M. E.; Kessler, B. M.; Fisher, R.; Trede, N. S.; Sezgin, E.; Maizels, R. M.; Hollander, G. A.
10.1101/2020.08.11.246215 — immunology — Posted on 2020-08-11
3056 Opposing activities of IFITM proteins in SARS-CoV-2 infection
Shi, G.; Kenney, A. D.; Kudryashova, E.; Zhang, L.; Hall-Stoodley, L.; Robinson, R.; Kudryashov, D.; Compton, A. A. S.; Yount, J. S.
10.1101/2020.08.11.246678 — immunology — Posted on 2020-08-11
3057 Development of CpG-adjuvanted stable prefusion SARS-CoV-2 spike antigen as a subunit vaccine against COVID-19
Kuo, T.-Y.; Lin, M.-Y.; Coffman, R. L.; Campbell, J. D.; Traquina, P.; Lin, Y.-J.; Liu, L. T. C.; Cheng, J.; Wu, Y.-C.; Wu, C.-C.; Tang, W.-H.; Huang, C.-G.; Tsao, K.-C.; Shih, S.-R.; Chen, C.
10.1101/2020.08.11.245704 — immunology — Posted on 2020-08-11
3058 Dietary propionate induces intestinal oxidative stress via inhibition of SIRT3-mediated SOD2 depropionylation
Ding, Q.; Zhang, Z.; Li, Y.; Liu, H.; Hao, Q.; Yang, Y.; Ringo, E.; Olsen, R. E.; Liu Clarke, J.; Ran, C.; Zhou, Z.
10.1101/2020.08.10.245399 — cell biology — Posted on 2020-08-11
3060 Interruption in POSTN-ITGAV axis affects lympho-hematopoiesis in mouse spleen
Mehatre, S. H.; Roy, I. M.; Biswas, A.; Prit, D.; Schouteden, S.; Huelsken, J.; Verfaillie, C. M.; Khurana, S.
10.1101/2020.08.11.236083 — immunology — Posted on 2020-08-11
3061 The identity of human tissue-emigrant CD8+ T cells
Buggert, M.; Vella, L. A.; Nguyen, S.; Wu, V.; Sekine, T.; Perez-Potti, A.; Maldini, C. R.; Manne, S.; Darko, S.; Ransier, A.; Kuri-Cervantes, L.; Sada Japp, A.; Bukh Brody, I.; Ivarsson, M. A.; Hertwig, L.; Antel, J. P.; Johnson, M. E.; Okoye, A.; Picker, L. J.; Vahedi, G.; Sparrelid, E.; Llewellyn-Lacey, S.; Gostick, E.; Bjorkstrom, N. K.; Bar-Or, A.; Dori, Y.; Naji, A.; Canaday, D.; Laufer, T. M.; Wells, A. D.; Price, D.; Frank, I.; Douek, D.; Wherry, E. J.; Itkin, M. G.; Betts, M. R.
10.1101/2020.08.11.236372 — immunology — Posted on 2020-08-11
3063 Linkage Disequilibrium and Heterozygosity Modulate the Genetic Architecture of Human Complex Phenotypes
Holland, D.; Frei, O.; Desikan, R.; Fan, C. C.; Shadrin, A.; Smeland, O.; Andreassen, O. A.; Dale, A.
10.1101/705285 — genomics — Posted on 2020-08-11
3064 A population of CD4+ T cells with a naive phenotype stably polarized to the TH1 lineage
Lo, J. W. P.; Vila de Mucha, M.; Roberts, L. B.; Garrido-Mesa, N.; Hertweck, A.; Neves, J. F.; Stolarczyk, E.; Henderson, S.; Jackson, I.; Howard, J. K.; Jenner, R. G.; Lord, G. M.
10.1101/2020.07.14.202168 — immunology — Posted on 2020-08-11
3066 Different mutant RUNX1 oncoproteins program alternate haematopoietic differentiation trajectories
Kellaway, S. G.; Keane, P.; Edginton-White, B.; Kakkad, R.; Kennett, E.; Bonifer, C.
10.1101/2020.08.10.244657 — genomics — Posted on 2020-08-11
3068 A system-level gene regulatory network model for Plasmodium falciparum
Neal, M. L.; Wei, L.; Peterson, E.; Arrieta-Ortiz, M. L.; Danziger, S. A.; Baliga, N. S.; Kaushansky, A.; Aitchison, J. D.
10.1101/2020.08.10.235317 — systems biology — Posted on 2020-08-10
3075 The histidine phosphotransfer AHP4 plays a negative role in Arabidopsis plant response to drought
Ha, c. v.; Nguyen, K. H.; Mostofa, M. G.; Tran, C. D.; Watanabe, Y.; Li, W.; Osakabe, Y.; Sato, M.; Toyooka, K.; Tanaka, M.; Seki, M.; Burritt, D. J.; Anderson, C.; Zhang, R.; Tran, S. P.-L.
10.1101/2020.07.30.229971 — plant biology — Posted on 2020-08-10
3076 Mechanical stimulation of endocardial Purkinje fibres can trigger ventricular arrhythmias
c, E.; Walton, R. D.; Kaur, S.; Power, A.; Haissaguerre, M.; Bernus, O.; Ward, M.-L.
10.1101/2020.08.10.234195 — physiology — Posted on 2020-08-10
3078 Sofosbuvir Terminated RNA is More Resistant to SARS-CoV-2 Proofreader than RNA Terminated by Remdesivir
Jockusch, S.; Tao, C.; Li, X.; Chien, M.; Kumar, S.; Morozova, I.; Kalachikov, S.; Russo, J. J.; Ju, J.
10.1101/2020.08.07.242156 — pharmacology and toxicology — Posted on 2020-08-10
3081 Cell Programmed Nutrient Partitioning in the Tumor Microenvironment
Reinfeld, B. I.; Madden, M. Z.; Wolf, M. M.; Chytil, A.; Bader, J. E.; Patterson, A. R.; Cohen, A. S.; Ali, A.; Do, B. T.; Lewis, C. A.; Muir, A.; Hongo, R. A.; Young, K. L.; Brown, R. E.; Todd, V. M.; Huffstater, T.; Abraham, A.; O'Neil, R. T.; Wilson, M. T.; Xin, F.; Tantawy, M. N.; Merryman, W. D.; Johnson, R. W.; Williams, C. S.; Mason, E. F.; Mason, F. M.; Beckermann, K. E.; Vander Heiden, M. G.; Manning, H. C.; Rathmell, J. C.; Rathmell, W. K.
10.1101/2020.08.10.238428 — cancer biology — Posted on 2020-08-10
3082 Mutant-selective Degradation by BRAF-targeting PROTACs
Alabi, S.; Jaime-Figueroa, S.; Yao, Z.; Gao, Y.; Hines, J.; Samarasinghe, K. . T. G.; Vogt, L.; Rosen, N.; Crews, C. M.
10.1101/2020.08.10.245159 — cancer biology — Posted on 2020-08-10
3084 Modeling Heterogeneity of Triple-Negative Breast Cancer Uncovers a Novel Combinatorial Treatment Overcoming Primary Drug Resistance
Lamballe, F.; Ahmad, F.; Vinik, Y.; Castellanet, O.; Daian, F.; Mueller, A.; Koehler, U.; Bailly, A.-L.; Josselin, E.; Castellano, R.; Cayrou, C.; Charafe-Jauffret, E.; Mills, G. B.; Geli, V.; Borg, J.-P.; Lev, S.; Maina, F.
10.1101/2020.06.22.164418 — cancer biology — Posted on 2020-08-10
3085 Computational Tool for Ensemble Averaging of Single-Molecule Data
Blackwell, T. J.; Stump, W. T.; Clippinger, S. R.; Greenberg, M. J.
10.1101/2020.08.10.241752 — biophysics — Posted on 2020-08-10
3088 TRPV2 interaction with small molecules and lipids revealed by cryo-EM
Protopopova, A. D.; Pumroy, R. A.; de la Roche, J.; Haug, F. M.; Sousa, B. B.; Gallo, P. N.; Bernardes, G. J. L.; Leffler, A.; Moiseenkova-Bell, V.
10.1101/2020.08.10.242008 — biophysics — Posted on 2020-08-10
3089 Ebselen Reacts with SARS Coronavirus-2 Main Protease Crystals
Malla, T. N.; Pandey, S.; Poudyal, I.; Feliz, D.; Noda, M.; Phillips, G.; Stojkovic, E.; Schmidt, M.
10.1101/2020.08.10.244525 — biophysics — Posted on 2020-08-10
3090 Bi-paratopic and multivalent human VH domains neutralize SARS-CoV-2 by targeting distinct epitopes within the ACE2 binding interface of Spike
Bracken, C. J.; Lim, S. A.; Solomon, P.; Rettko, N. J.; Nguyen, D. P.; Zha, B. S.; Schaefer, K.; Byrnes, J. R.; Zhou, J.; Lui, I.; Liu, J.; Pance, K.; QCRG Structural Biology Consortium, ; Zhou, X. X.; Leung, K. K.; Wells, J. A.
10.1101/2020.08.08.242511 — bioengineering — Posted on 2020-08-10
3091 Acidic monosaccharides become incorporated into calcite single crystals
Lang, A.; Mijowska, S.; Polishchuk, I.; Falini, G.; Fermani, S.; Katsman, A.; Marin, F.; Pokroy, B.
10.1101/2020.08.03.234310 — bioengineering — Posted on 2020-08-10
3095 Receptor tyrosine kinases activate heterotrimeric G proteins via phosphorylation within the interdomain cleft of Gαi
Kalogriopoulos, N.; Lopez-Sanchez, I.; Lin, C.; Ngo, T.; Midde, K.; Roy, S.; Aznar, N.; Murray, F.; Garcia-Marcos, M.; Kufareva, I.; Ghassemian, M.; Ghosh, P.
10.1101/2020.08.09.229716 — biochemistry — Posted on 2020-08-10
3096 D-Serine, an emerging biomarker of kidney diseases, is a hidden substrate of sodium-coupled monocarboxylate transporters
Wiriyasermkul, P.; Moriyama, S.; Tanaka, Y.; Kongpracha, P.; Nakamae, N.; Suzuki, M.; Kimura, T.; Mita, M.; Sasabe, J.; Nagamori, S.
10.1101/2020.08.10.244822 — biochemistry — Posted on 2020-08-10
3097 An ultra-high affinity synthetic nanobody blocks SARS-CoV-2 infection by locking Spike into an inactive conformation
Schoof, M.; Faust, B.; Saunders, R. A.; Sangwan, S.; Rezelj, V. V.; Hoppe, N.; Boone, M.; Billesboelle, C.; Zimanyi, M.; Deshpande, I.; Liang, J.; Anand, A. A.; Dobzinski, N.; Zha, B. S.; Barsi-Rhyne, B.; Bleyy, V.; Barile-Hill, A. W.; Gupta, S.; Simoneau, C. R.; Leon, K.; White, K. M.; Nock, S.; Liu, Y.; Krogan, N. J.; Ralston, C. Y.; Swaney, D. L.; Garcia-Sastre, A.; Ott, M.; Vignuzzi, M.; Quantitative Biosciences Institute (QBI) Coronavirus Research Group Structural Biology Consortium, ; Walter, P.; Manglik, A.
10.1101/2020.08.08.238469 — biochemistry — Posted on 2020-08-10
3099 Structure-function analyses of dual-BON domain protein DolP identifies phospholipid binding as a new mechanism for protein localisation
Bryant, J. A.; Morris, F.; Knowles, T. J.; Maderbocus, R.; Heinz, E.; Boelter, G.; Alodaini, D.; Colyer, A.; wotherspoon, P.; Staunton, K.; Jeeves, M.; Browning, D.; Sevastsyanovich, Y.; Wells, T.; Rossiter, A.; Bavro, V.; Sridhar, P.; Ward, D.; Chong, Z.-S.; Icke, C.; Teo, A.; Chng, S. S.; Roper, D.; Lithgow, T. J.; Cunningham, A. F.; Banzhaf, M.; Overduin, M.; henderson, i.
10.1101/2020.08.10.244616 — biochemistry — Posted on 2020-08-10
3102 Social predation in electric eels
Bastos, D. A.; Zuanon, J.; Py-Daniel, L. R.; de Santana, C. D.
10.1101/2020.08.10.244129 — animal behavior and cognition — Posted on 2020-08-10
3104 Measuring reading ability in the web-browser with a lexical decision task
Yeatman, J. D.; Tang, K. A.; Donnelly, P. M.; Yablonski, M.; Ramamurthy, M.; Karipidis, I. I.; Caffarrra, S.; Takada, M. E.; Ben-Shachar, M.; Domingue, B. W.
10.1101/2020.07.30.229658 — animal behavior and cognition — Posted on 2020-08-10
3107 Ap2s1 mutation in mice causes familial hypocalciuric hypercalcemia type 3
Hannan, F. M.; Stevenson, M.; Bayliss, A. L.; Stokes, V. j.; Stewart, M. E.; Kooblall, K. G.; Gorvin, C. M.; Codner, G. F.; Teboul, L.; Wells, S.; Thakker, R. V.
10.1101/2020.08.10.244244 — genetics — Posted on 2020-08-10
3110 Rapid evolution drives the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection
Wheatley, R.; Diaz Caballero, J.; Kapel, N.; Quinn, A.; del Barrio-Tofino, E.; Lopez-Causape, C.; Hedge, J.; Torrens, G.; Van der Schalk, T.; Britto Xavier, B.; Fernandez-Cuenca, F.; Arenzana, A.; Recanatini, C.; Timbermont, L.; Sifakis, F.; Ruzin, A.; Ali, O.; Lammens, C.; Goossens, H.; Kluytmans, J.; Kumar-Singh, S.; Oliver, A.; Malhotra-Kumar, S.; MacLean, C.
10.1101/2020.08.10.243741 — evolutionary biology — Posted on 2020-08-10
3111 Unidirectional response to bidirectional selection on body size. I. Phenotypic, life history and endocrine response.
Renneville, C.; Millot, A.; Agostini, S.; Carmignac, D.; Maugars, G.; Dufour, S.; Le Rouzic, A.; Edeline, E.
10.1101/498683 — evolutionary biology — Posted on 2020-08-10
3112 Density-dependent selection mediates harvest-induced trait changes
Bouffet-Halle, A.; Mériguet, J.; Carmignac, D.; Agostini, S.; Millot, A.; Perret, S.; Motard, E.; Decenciere, B.; Edeline, E.
10.1101/561522 — evolutionary biology — Posted on 2020-08-10
3121 Dach1 extends artery networks and protects against cardiac injury
Raftrey, B.; Williams, I. M.; Rios Coronado, P. E.; Chang, A. H.; Zhao, M.; Roth, R.; Racelis, R.; D'Amato, G.; Phansalkar, R.; Gonzalez, K. M.; Zhang, Y.; Bernstein, D.; Red-Horse, K.
10.1101/2020.08.07.242164 — developmental biology — Posted on 2020-08-10
3122 Identification of limb-specific Lmx1b auto-regulatory modules with Nail-Patella Syndrome pathogenicity.
Haro, E.; Petit, F.; Pira, C. U.; Spady, C. D.; Ivey, L. A.; Gray, A. L.; Escande, F.; Jourdain, A.-S.; Nguyen, A.; Fellmann, F.; Good, J.-M.; Francannet, C.; Manouvrier-Hanu, S.; Ros, M. A.; Oberg, K. C.
10.1101/2020.08.10.243915 — developmental biology — Posted on 2020-08-10
3124 PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells
De Smedt, J.; van Os, E. A.; Talon, I.; Ghosh, S.; Toprakhisar, B.; Furtado Madeiro Da Costa, R.; Zaunz, S.; Aguirre Vazquez, M.; Boon, R.; Baatsen, P.; Smout, A.; Verhulst, S.; van Grunsven, L. A.; Verfaillie, C. M.
10.1101/2020.08.10.244517 — developmental biology — Posted on 2020-08-10
3125 The BMP antagonist Gremlin1 contributes to the development of cortical excitatory neurons, motor balance and fear responses
Ichinose, M.; Suzuki, N.; Wang, T.; Kobayashi, H.; Vrbanac, L.; Ng, J. Q.; Wright, J. A.; Lannagan, T. R.; Gieniec, K. A.; Lewis, M.; Ando, R.; Enomoto, A.; Koblar, S.; Thomas, P.; Worthley, D. L.; Woods, S. L.
10.1101/2020.07.24.219394 — developmental biology — Posted on 2020-08-10
3126 PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates
Xu, Y.-f.; Sun, J.; Yu, X.; Chen, X.; Cui, M.; Yang, Z.; Liu, C.-h.; Yang, X.-z.; Wang, Y.-j.; Zhang, S.; Wang, C.; Zhang, Z.-y.; Zhao, W.-d.; Wang, C.-h.; Ji, Z.-l.; Xiao, P.; Li, K.-s.; Xu, Z.-G.; Zhu, Z.-L.
10.1101/822031 — cell biology — Posted on 2020-08-10
3127 Somatic mosaicism in the mature brain reveals clonal cellular distributions during cortical development
Breuss, M. W.; Yang, X.; Antaki, D.; Schlachetzki, J. C. M.; Lana, A. A.; Xu, X.; Chai, G.; Stanley, V.; Song, Q.; Fang Newmeyer, T.; Nguyen, A.; Cao, B.; Nott, A.; McEvoy-Venneri, J.; Pasillas, M. P.; Nahas, S.; Van Der Kraan, L.; Ding, Y.; NIMH Brain Somatic Mosaicism Network, ; Glass, C. K.; Gleeson, J. G.
10.1101/2020.08.10.244814 — genomics — Posted on 2020-08-10
3129 Refinement of Genome assemblies of Pigeonpea (Cajanus cajan)
Marla, S. S.; Mishra, P.; Maurya, R.; Singh, M.; Wankhade, D. P.; Gupta, A. K.; N, S. R.; Singh, S. K.; Kumar, R.
10.1101/2020.08.10.243949 — genomics — Posted on 2020-08-10
3131 Insights into dispersed duplications and complex structural mutations from whole genome sequencing 706 families
Whelan, C. W.; Handsaker, R. E.; Genovese, G.; Kashin, S.; Lek, M.; Hughes, J.; McElwee, J.; Lenardo, M.; MacArthur, D.; McCarroll, S. A.
10.1101/2020.08.03.235358 — genomics — Posted on 2020-08-10
3132 Antigen-Specific T Cell Recall Assay To Screen Drugs For Off-Target Effects
Kleiman, E.; Sierra, G.; Magcase, D.; George, M. V.; Daftarian, P. M.
10.1101/2020.08.10.241869 — immunology — Posted on 2020-08-10
3133 A comparison of non-magnetic and magnetic beads for measuring IgG antibodies against P. vivax antigens in a multiplexed bead-based assay using Luminex(R) technology (Bio-Plex(R)200 or MAGPIX(R))
Mazhari, R.; Brewster, J.; Fong, R.; Bourke, C.; Liu, Z. S.; Takashima, E.; Tsuboi, T.; Tham, W.-H.; Harbers, M.; Chitnis, C.; Healer, J.; Ome-Kaius, M.; Sattabongkot, J.; Kazura, J.; Robinson, L.; King, C.; Mueller, I.; Longley, R.
10.1101/2020.08.10.243980 — immunology — Posted on 2020-08-10
3134 Immunomodulatory effects of cytokine-induced expansion of cytotoxic lymphocytes in a mouse model of lupus-like disease
Reighard, S. D.; Krishnamurthy, D.; Cevik, H.; Ohayon, D. E.; Ali, A.; Seelamneni, H.; Brunner, H. I.; Waggoner, S. N.
10.1101/815399 — immunology — Posted on 2020-08-10
3135 Nonstructural protein 1 of SARS-CoV-2 is a potent pathogenicity factor redirecting host protein synthesis machinery toward viral RNA.
Yuan, S.; Peng, L.; Park, J. J.; Hu, Y.; Devarkar, S. C.; Dong, M. B.; Wu, S.; Chen, S.; Lomakin, I.; Xiong, Y.
10.1101/2020.08.09.243451 — molecular biology — Posted on 2020-08-10
3136 The PNUTS-PP1 axis regulates endothelial aging and barrier function via SEMA3B suppression
Lozano-Vidal, N.; Stanicek, L.; Bink, D. I.; Kremer, V.; MacInnes, A. W.; Dimmeler, S.; Boon, R. A.
10.1101/2020.08.10.243170 — molecular biology — Posted on 2020-08-10
3140 CoRhythMo: A Computational Framework for Modeling Biobehavioral Rhythms from Mobile and Wearable Data Streams
Yan, R.; Liu, X.; Dutcher, J.; Tumminia, M.; Villalba, D.; Cohen, S.; Creswell, D.; Creswell, K.; Mankoff, J.; Dey, A.; Doryab, A.
10.1101/2020.08.10.244020 — bioinformatics — Posted on 2020-08-10
3143 EUAdb: a resource for COVID-19 test development
Woronik, A.; Shaffer, H. W.; Kiontke, K.; Laurent, J. M.; Zambrano, R.; Boeke, J. D.; Fitch, D. H. A.
10.1101/2020.07.30.228890 — bioinformatics — Posted on 2020-08-10
3144 On the complexity of haplotyping a microbial community
Nicholls, S. M.; Aubrey, W.; de Grave, K.; Schietgat, L.; Creevey, C. J. M.; Clare, A.
10.1101/2020.08.10.244848 — bioinformatics — Posted on 2020-08-10
3145 AutoSpill: A method for calculating spillover coefficients to compensate or unmix high-parameter flow cytometry data
Roca, C. P.; Burton, O. T.; Prezzemolo, T.; Whyte, C. E.; Halpert, R.; Kreft, Łukasz; Collier, J.; Botzki, A.; Spidlen, J.; Humblet-Baron, S.; Liston, A.
10.1101/2020.06.29.177196 — bioinformatics — Posted on 2020-08-10
3147 Bmp8a Is a Novel Player in Regulation of Antiviral Immunity
Zhong, S.; Li, H.; Wang, Y.; Wang, Y.; Ji, G.; Li, H.; Zhang, S.; Liu, Z.
10.1101/2020.08.09.243519 — immunology — Posted on 2020-08-10
3148 Modulation of macrophage inflammatory function through selective inhibition of the epigenetic reader protein SP140
Ghiboub, M.; Koster, J.; Craggs, P. D.; Li Yim, A. Y. F.; Shillings, A.; Hutchinson, S.; Bingham, R. P.; Gatfield, K.; Hageman, I. L.; Yao, G.; O'Keefe, H. P.; Coffin, A.; Patel, A.; Sloan, L. A.; Mitchell, D. J.; Lunven, L.; Watson, R. J.; Blunt, C. E.; Harrison, L. A.; Bruton, G.; Kumar, U.; Hamer, N.; Spaull, J. R.; Zwijnenburg, D. A.; Welting, O.; Hakvoort, T. B. M.; van Limbergen, J.; Henneman, P.; Prinjha, R. K.; de Winther, M. P.; Harker, N. R.; Tough, D. F.; de Jonge, W. J.
10.1101/2020.08.10.239475 — immunology — Posted on 2020-08-10
3149 SARS-CoV-2 neutralization and serology testing of COVID-19 convalescent plasma from donors with non-severe disease
Gniadek, T. J.; Thiede, J. M.; Matchett, W. E.; Gress, A. R.; Pape, K. A.; Jenkins, M. K.; Menachery, V. D.; Langlois, R. A.; Bold, T. D.
10.1101/2020.08.07.242271 — immunology — Posted on 2020-08-10
3150 DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist
Thepaut, M.; Luczkowiak, J.; Vives, C.; Labiod, N.; Bally, I.; Lasala, F.; Grimoire, Y.; Fenel, D.; Sattin, S.; Thielens, N.; Schoehn, G.; Bernardi, A.; Delgado, R.; Fieschi, F.
10.1101/2020.08.09.242917 — immunology — Posted on 2020-08-10
3151 Comparative analyses of SARS-CoV-2 binding (IgG, IgM, IgA) and neutralizing antibodies from human serum samples
Mazzini, L.; Martinuzzi, D.; Hyseni, I.; Lapini, G.; Benincasa, L.; Piu, P.; Trombetta, C. M.; Marchi, S.; Razzano, I.; Manenti, A.; Montomoli, E.
10.1101/2020.08.10.243717 — immunology — Posted on 2020-08-10
3152 A Broadly Neutralizing Macaque Monoclonal Antibody Against the HIV-1 V3-Glycan Patch
Wang, Z.; Barnes, C. O.; Gautam, R.; Cetrulo Lorenzi, J. C.; Mayer, C. T.; Oliveira, T. Y.; Ramos, V.; Cipolla, M.; Gordon, K. M.; Gristick, H. B.; West, A. P.; Nishimura, Y.; Raina, H.; Seaman, M. S.; Gazumyan, A.; Martin, M. A.; Bjorkman, P. J.; Escolano, A.; Nussenzweig, M. C.
10.1101/2020.08.10.244582 — immunology — Posted on 2020-08-10
3153 Early Alpine human occupation backdates westward human migration in Late Glacial Europe
Bortolini, E.; Pagani, L.; Oxilia, G.; Posth, C.; Fontana, F.; Badino, F.; Saupe, T.; Montinaro, F.; Margaritora, D.; Romandini, M.; Lugli, F.; Papini, A.; Boggioni, M.; Perrini, N.; Oxilia, A.; Aiese Cigliano, R.; Barcelona, R.; Visentin, D.; Fasser, N.; Arrighi, S.; Figus, C.; Marciani, G.; Silvestrini, S.; Bernardini, F.; Menghi Sartorio, J. C.; Fiorenza, L.; Moggi Cecchi, J.; Tuniz, C.; Kivisild, T.; Gianfrancesco, F.; Peresani, M.; Scheib, C. L.; Talamo, S.; D'Esposito, M.; Benazzi, S.
10.1101/2020.08.10.241430 — genomics — Posted on 2020-08-10
3154 High throughput detection and genetic epidemiology of SARS-CoV-2 using COVIDSeq next generation sequencing
Bhoyar, R. C.; Jain, A.; Sehgal, P.; Divakar, M. K.; Sharma, D.; Imran, M.; Jolly, B.; Ranjan, G.; Rophina, M.; Sharma, S.; Siwach, S.; Pandhare, K.; Sahoo, S.; Sahoo, M.; Nayak, A.; Mohanty, J. N.; Das, J.; Bhandari, S.; Mathur, S. K.; Kumar, A.; Sahlot, R.; Rojarani, P.; Vijaya Lakshmi, J.; Surekha, A.; Sekhar, P. C.; Mahajan, S.; Masih, S.; Singh, P.; Kumar, V.; Jose, B.; Mahajan, V.; Gupta, V.; Gupta, R.; Arumugam, P.; Singh, A.; Nandy, A.; P.V., R.; Jha, R. M.; Kumari, A.; Gandotra, S.; Rao, V.; Faruq, M.; Kumar, S.; Reshma G, B.; Varma, N. G.; Shekhar Roy, S.; Sengupta, A.; Chattopadhyay
10.1101/2020.08.10.242677 — genomics — Posted on 2020-08-10
3155 Petabase-scale sequence alignment catalyses viral discovery
Edgar, R. C.; Taylor, J.; Altman, T.; Barbera, P.; Meleshko, D.; Lin, V.; Lohr, D.; Novakovsky, G.; Al-Shayeb, B.; Banfield, J.; Korobeynikov, A.; Chikhi, R.; Babaian, A.
10.1101/2020.08.07.241729 — bioinformatics — Posted on 2020-08-10
3158 Rapid-Eye-Movement Sleep Behavior Disorder Exhibits Similar but Distinct Gut Dysbiosis Compared to Parkinson's Disease
Nishiwaki, H.; Hamaguchi, T.; Ito, M.; Ishida, T.; Maeda, T.; Kashihara, K.; Yoshio, T.; Ueyama, J.; Teppei, S.; Mori, H.; Kurokawa, K.; Katsuno, M.; Hirayama, M.; Ohno, K.
10.1101/2020.08.07.242453 — microbiology — Posted on 2020-08-10
3160 Modulation of kinase activity within a bacterial membraneless organelle
Saurabh, S.; Chong, T. N.; Bayas, C.; Dahlberg, P. D.; Cartwright, H. N.; Moerner, W. E.; Shapiro, L.
10.1101/2020.08.09.232405 — microbiology — Posted on 2020-08-10
3161 Deeply sequenced infectious clones of key cassava begomovirus isolates from Cameroon
Hoyer, J. S.; Fondong, V. N.; Dallas, M. M.; Aimone, C. D.; Deppong, D. O.; Duffy, S.; Hanley-Bowdoin, L.
10.1101/2020.08.10.244335 — microbiology — Posted on 2020-08-10
3162 Durable Control of HIV-1 Using a Staphylococcus aureus Cas9-Expressing Lentivirus Co-Targeting Viral Latency and Host Susceptibility
Chavez, L. R.; Reddy, N. R.; Raymond, K. A.; Bouzidi, M. S.; Desai, S.; Dossani, Z. Y.; Sperber, H. S.; Theiler, J.; Korber, B.; Pillai, S. K.
10.1101/2020.08.10.243329 — microbiology — Posted on 2020-08-10
3167 Temporal changes in the gut microbiota in farmed Atlantic cod (Gadus morhua) outweigh the response to diet supplementation with macroalgae.
Keating, C.; Bolton-Warberg, M.; Hinchcliffe, J.; Davies, R.; Whelan, S.; Wan, A. H.; Fitzgerald, R.; Davies, S. J.; Ijaz, U. Z.; Smith, C. J.
10.1101/2020.08.10.222604 — microbiology — Posted on 2020-08-10
3169 Characterization of SARS-CoV-2 ORF6 deletion variants detected in a nosocomial cluster during routine genomic surveillance, Lyon, France
Queromes, G.; Destras, G.; Bal, A.; Regue, H.; Burfin, G.; Brun, S.; Fanget, R.; Morfin, F.; Valette, M.; Lina, B.; Frobert, E.; Josset, L.
10.1101/2020.08.07.241653 — microbiology — Posted on 2020-08-10
3170 K18-hACE2 Mice for Studies of COVID-19 Treatments and Pathogenesis Including Anosmia
Perlman, S.; Zheng, J.; WONG, L. Y. R.; Li, K.; Verma, A. K.; Ortiz Bezara, M. E.; Wohlford-Lenane, C.; Leidinger, M. R.; Kundson, M. C.; Meyerholz, D. K.; McCray, P. B.
10.1101/2020.08.07.242073 — microbiology — Posted on 2020-08-10
3171 SARS-CoV-2 Quasispecies Mediate Rapid Virus Evolution and Adaptation
Chaudhry, M. Z.; Eschke, K.; Grashoff, M.; Abassi, L.; Kim, Y.; Brunotte, L.; Ludwig, S.; Safranko, Z. M.; Kurolt, I.-C.; Markotic, A.; Kroeger, A.; Klawonn, F.; Cicin-Sain, L.
10.1101/2020.08.10.241414 — microbiology — Posted on 2020-08-10
3173 The role of prolines and glycine in transmembrane domain of LAT
Glatzova, D.; Mavila, H.; Saija, M. C.; Chum, T.; Cwiklik, L.; Brdicka, T.; Cebecauer, M.
10.1101/2020.08.10.244251 — cell biology — Posted on 2020-08-10
3176 Engineered Reproductively Isolated Species Drive Reversible Population Replacement
Buchman, A.; Shriner, I.; Yang, T.; Liu, J.; Antoshechkin, I.; Marshall, J. M.; Perry, M. W.; Akbari, O. S.
10.1101/2020.08.09.242982 — bioengineering — Posted on 2020-08-10
3178 Capturing Neonatal Cardiomyocyte - Endothelial interactions on-a-Chip
Tavassoli, H.; Kang, Y. C.; Rorimpandey, P.; Pimanda, J. E.; Chandrakanthan, V.; Chan, P. P. Y.
10.1101/2020.08.10.243600 — bioengineering — Posted on 2020-08-10
3179 A potent neutralizing nanobody against SARS-CoV-2 with inhaled delivery potential
Gai, J.; Ma, L.; Li, G.; Zhu, M.; Qiao, P.; Li, X.; Zhang, H.; Zhang, Y.; Chen, Y.; Gong, R.; Wan, Y.
10.1101/2020.08.09.242867 — bioengineering — Posted on 2020-08-10
3181 Inhibition of histone readers bromodomain extra-terminal proteins alleviates scleroderma fibrosis
Vichaikul, S.; Palisoc, P. J.; Ali, M.; Campbell, P. L.; Amin, M. A.; Ruth, J. H.; Rohraff, D. M.; Hervoso, J. L.; Fox, D. A.; Khanna, D.; Sawalha, A.; Tsou, P.-S.
10.1101/2020.08.07.242198 — pharmacology and toxicology — Posted on 2020-08-10
3183 Improving cell-specific drug connectivity mapping with collaborative filtering
Newman, R.; Pietras, C. M.; Qu, F.; Sapashnik, D.; Kofman, L.; Butze, S.; Ocitti, F.; Fried, I.; Slonim, D.
10.1101/2020.08.10.231720 — bioinformatics — Posted on 2020-08-10
3185 Zbtb16 regulates social cognitive behaviors and neocortical development.
Usui, N.; Berto, S.; Konishi, A.; Kondo, M.; Konopka, G.; Matsuzaki, H.; Shimada, S.
10.1101/2020.08.09.233270 — neuroscience — Posted on 2020-08-10
3195 Predictability in natural images determines V1 firing rates and synchronization: A deep neural network approach
Uran, C.; Peter, A. S.; Lazar, A.; Barnes, W.; Klon-Lipok, J.; Shapcott, K. A.; Roese, R.; Fries, P.; Singer, W.; Vinck, M.
10.1101/2020.08.10.242958 — neuroscience — Posted on 2020-08-10
3198 Brain-wide mapping of neural activity mediating collicular-dependent behaviors
Sans-Dublanc, A.; Chrzanowska, A.; Reinhard, K.; Lemmon, D.; Montaldo, G.; Urban, A.; Farrow, K.
10.1101/2020.08.09.242875 — neuroscience — Posted on 2020-08-10
3200 Alcohol boosts pheromone production in male flies and makes them sexier
Keesey, I. W.; Doll, G.; Das Chakraborty, S.; Baschwitz, A.; Lemoine, M.; Kaltenpoth, M.; Svatos, A.; Sachse, S.; Knaden, M.; Hansson, B. S.
10.1101/2020.08.09.242784 — neuroscience — Posted on 2020-08-10
3201 Anatomical modeling of brain vasculature in two-photon microscopy by generalizable deep learning
Tahir, W.; Kura, S.; Zhu, J.; Cheng, X.; Damseh, R.; Tadesse, F.; Seibel, A.; Lee, B. S.; Lesage, F.; Sakadzic, S.; Boas, D. A.; Tian, L.
10.1101/2020.08.09.243394 — neuroscience — Posted on 2020-08-10
3203 The tiny Cretaceous stem-bird Oculudentavis revealed as a bizarre lizard
Bolet, A.; Stanley, E. L.; Daza, J. D.; Arias, J. S.; Cernansky, A.; Vidal-Garcia, M.; Bauer, A. M.; Bevitt, J. J.; Peretti, A.; Evans, S. E.
10.1101/2020.08.09.243048 — paleontology — Posted on 2020-08-10
3206 A Uropathogenic E. coli UTI89 model of prostatic inflammation and collagen accumulation for use in studying aberrant collagen production in the prostate
RUETTEN, H. M.; Sandhu, J.; Mueller, B.; Wang, P.; Zhang, H. L.; Wegner, K. A.; Cadena, M.; Sandhu, S.; Abler, L.; Zhu, J.; O'Driscoll, C. A.; Chelgren, B.; Wang, Z.; Shen, T.; Barasch, J.; Bjorling, D. E.; Vezina, C. M.
10.1101/2020.08.10.238196 — physiology — Posted on 2020-08-10
3209 Urinary proteome profiling for stratifying patients with familial Parkinsons disease
Virreira Winter, S.; Karayel, O.; Strauss, M. T.; Padmanabhan, S.; Surface, M.; Merchant, K.; Alcalay, R. N.; Mann, M.
10.1101/2020.08.09.243584 — systems biology — Posted on 2020-08-10
3210 Reproducibility in systems biology modelling
Tiwari, K.; Kananathan, S.; Roberts, M. G.; Meyer, J. P.; Sharif Shohan, M. U.; Xavier, A.; Maire, M.; Zyoud, A.; Men, J.; Ng, S.; Nguyen, T. V. N.; Glont, M.; Hermjakob, H.; Malik Sheriff, R. S.
10.1101/2020.08.07.239855 — systems biology — Posted on 2020-08-10
3212 The inner membrane protein YhdP modulates the rate of anterograde phospholipid flow in Escherichia coli
Grimm, J.; Shi, H.; Wang, W.; Mitchell, A. M.; Wingreen, N. S.; Huang, K. C.; Silhavy, T. J.
10.1101/2020.08.09.213157 — molecular biology — Posted on 2020-08-10
3216 A comprehensive transcriptome signature of murine hematopoietic stem cell aging
Svendsen, A. F.; Yang, D.; Lazare, S.; Zwart, E.; Ausema, A.; de Haan, G.; Bystrykh, L.
10.1101/2020.08.10.244434 — cell biology — Posted on 2020-08-10
3218 Patient-derived xenograft culture-transplant system for investigation of human breast cancer metastasis
Ma, D.; Hernandez, G. A.; Lefebvre, A. E. Y. T.; Alshetaiwi, H.; Blake, K.; Dave, K. R.; Rauf, M.; Williams, J. W.; Davis, R. T.; Evans, K. T.; Masoud, M. Y. G.; Lee, R.; Edwards, R. A.; Digman, M. A.; Kessenbrock, K.; Lawson, D. A.
10.1101/2020.06.25.172056 — cancer biology — Posted on 2020-08-10
3219 An AI-powered blood test to detect cancer using nanoDSF
Tsvetkov, P. O.; Eyraud, R.; Ayache, S.; Bougaev, A. A.; Malesinski, S.; Benazha, H.; Gorokhova, S.; Buffat, C.; Dehais, C.; Sanson, M.; Bielle, F.; Figarella-Branger, D.; Chinot, O.; Tabouret, E.; Devred, F.
10.1101/2020.08.09.242818 — cancer biology — Posted on 2020-08-10
3222 Diversity and biogeography of Woesearchaeota: A comprehensive analysis of multi-environment data
Xiao, J.; Zhang, Y.; Chen, W.; Xu, Y.; Zhao, R.; Tao, L.; Wu, Y.; Zhang, Y.; Xiao, X.; Zhu, R.
10.1101/2020.08.09.243345 — ecology — Posted on 2020-08-10
3229 SPARC regulation of PMN clearance protects from pristane induced lupus and rheumatoid arthritis
Sangaletti, S.; Botti, L.; Gulino, A.; Lecis, D.; Bassani, B.; Portararo, P.; Milani, M.; De Cecco, L.; Dugo, M.; Tripodo, C.; Colombo, M. P.
10.1101/2020.08.10.243816 — immunology — Posted on 2020-08-10
3230 CD40 provides immune privilege to the bone marrow hematopoietic niche
Bassani, B.; Gulino, A.; Portararo, P.; Botti, L.; Cappetti, B.; Chiodoni, C.; Bolli, N.; Ciciarello, M.; Joehrens, K.; Anagnostopoulos, I.; Na, I.-K.; Curti, A.; Tripodo, C.; Colombo, M. P.; Sangaletti, S.
10.1101/2020.08.10.243691 — immunology — Posted on 2020-08-10
3231 Action Potentials and Na+ voltage-gated ion channels in Placozoa
Romanova, D. Y.; Smirnov, I. V.; Nikitin, M. A.; Kohn, A. B.; Borman, A.; Malyshev, A.; Balaban, P. M.; Moroz, L. L.
10.1101/2020.08.09.243113 — evolutionary biology — Posted on 2020-08-10
3236 The MRC IEU OpenGWAS data infrastructure
Elsworth, B. L.; Lyon, M. S.; Alexander, T.; Liu, Y.; Matthews, P.; Hallett, J.; Bates, P.; Palmer, T.; Haberland, V.; Davey Smith, G.; Zheng, J.; Haycock, P.; Gaunt, T. R.; Hemani, G.
10.1101/2020.08.10.244293 — genetics — Posted on 2020-08-10
3239 Agromonas: a rapid disease assay for Pseudomonas syringae growth in agroinfiltrated leaves
Buscaill, P.; Sanguankiattichai, N.; Lee, Y. J.; Kourelis, J.; Preston, G. M.; van der Hoorn, R. A. L.
10.1101/2020.08.10.243808 — plant biology — Posted on 2020-08-10
3242 Development of Putative Isospecific Inhibitors for HDAC6 using Random Forest, QM-Polarized docking, Induced-fit docking, and Quantum mechanics
Joel, I. y.; ADIGUN, T. O.; BANKOLE, O. O.; AJIBOLA, A. O.; OFENIFORO, E. B.; AUTA, F. B.; OZOJIOFOR, U. O.; REMI-ESAN, I. A.; AKANDE, A. I.
10.1101/2020.08.10.243824 — bioinformatics — Posted on 2020-08-10
3244 VIP-HL: Semi-automated ACMG/AMP variant interpretation platform for genetic hearing loss
Peng, J.; Xiang, J.; Jin, X.; Meng, J.; Song, N.; Chen, L.; Tayoun, A. A.; Peng, Z.
10.1101/2020.08.10.243642 — bioinformatics — Posted on 2020-08-10
3247 Comprehensive characterization of single cell full-length isoforms in human and mouse with long-read sequencing
Tian, L.; Jabbari, J. S.; Thijssen, R.; Gouil, Q.; Amarasinghe, S. L.; Kariyawasam, H.; Su, S.; Dong, X.; Law, C. W.; Lucattini, A.; Chung, J. D.; Naim, T.; Chan, A.; Ly, C. H.; Lynch, G. S.; Ryall, J. G.; Anttila, C. J. A.; Peng, H.; Anderson, M. A.; Roberts, A. W.; Huang, D. C. S.; Clark, M. B.; Ritchie, M. E.
10.1101/2020.08.10.243543 — genomics — Posted on 2020-08-10
3250 Rapid discovery of novel prophages using biological feature engineering and machine learning
Siren, K.; Millard, A.; Petersen, B.; Gilbert, M. T. P.; Clokie, M. R.; Sicheritz-Ponten, T.
10.1101/2020.08.09.243022 — bioinformatics — Posted on 2020-08-10
3251 Data Integration with SUMO Detects Latent Relationships Between Patients in Lower-Grade Gliomas
Sienkiewicz, K.; Chen, J.; Chatrath, A.; Lawson, J. T.; Sheffield, N. C.; Zhang, L.; Ratan, A.
10.1101/2020.08.10.244343 — bioinformatics — Posted on 2020-08-10
3253 Functional Organization of Midget and Parasol Ganglion Cells in the Human Retina
Kling, A.; Gogliettino, A. R.; Shah, N. P.; Wu, E. G.; Brackbill, N.; Sher, A.; Litke, A.; Silva, R. A.; Chichilnisky, E. J.
10.1101/2020.08.07.240762 — neuroscience — Posted on 2020-08-10
3254 A series of five population-specific Indian brain templates and atlases spanning ages 6 to 60 years
Holla, B.; Taylor, P. A.; Glen, D. R.; Lee, J. A.; Vaidya, N.; Mehta, U. M.; Venkatasubramanian, G.; Pal, P.; Saini, J.; Rao, N. P.; Ahuja, C.; Kuriyan, R.; Krishna, M.; Basu, D.; Kalyanram, K.; Chakrabarti, A.; Orfanos, D. P.; Barker, G. J.; Cox, R. W.; Schumann, G.; Bharath, R. D.; Benegal, V.
10.1101/2020.05.08.077172 — neuroscience — Posted on 2020-08-10
3261 Mobilization of a Kluyvera-like arnBCADTEF operon, besides mcr genes, confers colistin resistance to Escherichia coli isolated from healthy animals
Gallardo, A.; Iglesias, M. R.; Ugarte-Ruiz, M.; Hernandez, M.; Miguela-Villoldo, P.; Gutierrez, G.; Rodriguez-Lazaro, D.; Dominguez, L.; Quesada, A.
10.1101/2020.08.06.240812 — microbiology — Posted on 2020-08-08
3262 Hydration-dependent phase separation of a prion-like protein regulates seed germination during water stress.
Dorone, Y.; Boeynaems, S.; Jin, B.; Bossi, F.; Flores, E.; Lazarus, E.; Michiels, E.; De Decker, M.; Baatsen, P.; Holehouse, A. S.; Sukenik, S.; Gitler, A. D.; Rhee, S. Y.
10.1101/2020.08.07.242172 — cell biology — Posted on 2020-08-07
3265 Human Microbial Transplant Restores T Cell Cytotoxicity and Anti-Tumor Response to PD-L1 Blockade in Gnotobiotic Mice
Borgerding, J. N.; Shang, J.; Britton, G. J.; Salmon, H.; Bigenwald, C.; Maier, B.; Rose, S. R.; Mogno, I. J.; Kamphorst, A. O.; Merad, M.; Faith, J. J.
10.1101/2020.08.07.242040 — immunology — Posted on 2020-08-07
3267 Necator americanus Ancylostoma secreted protein-2 (Na-ASP-2) selectively binds an ascaroside (ascr#3)
El Atab, O.; Darwiche, R.; Truax, N. J.; Schneiter, R.; Hull, K. G.; Romo, D.; Asojo, O. A.
10.1101/2020.08.07.224964 — biochemistry — Posted on 2020-08-07
3268 Detecting fine and elaborate movements with piezo sensors, from heartbeat to the temporal organization of behavior
Carreno-Munoz, M. I.; Medrano, M. C.; Leinekugel, T.; Bompart, M.; Martins, F.; Subashi, E.; Aby, F.; Frick, A.; Landry, M.; Grana, M.; Leinekugel, X.
10.1101/2020.04.03.024711 — animal behavior and cognition — Posted on 2020-08-07
3269 Historical and contemporary signatures of selection in response to transmissible cancer in the Tasmanian Devil (Sarcophilus harrisii)
Stahlke, A. R.; Epstein, B.; Barbosa, S.; Patton, A.; Hendricks, S. A.; Veillet, A.; Fraik, A. K.; Schonfeld, B.; McCallum, H.; Hamede, R.; Jones, M. E.; Storfer, A.; Hohenlohe, P. A.
10.1101/2020.08.07.241885 — evolutionary biology — Posted on 2020-08-07
3272 Functional Organization of Midget and Parasol Ganglion Cells in the Human Retina
Kling, A.; Gogliettino, A. R.; Shah, N. P.; Wu, E. G.; Brackbill, N.; Sher, A.; Litke, A.; Silva, R. A.; Chichilnisky, E. J.
10.1101/2020.08.07.240762 — neuroscience — Posted on 2020-08-07
3274 Behavioral, physiological, and neural signatures of surprise during naturalistic sports viewing
Antony, J. W.; Hartshorne, T. H.; Pomeroy, K.; Gureckis, T. M.; Hasson, U.; McDougle, S. D.; Norman, K. A.
10.1101/2020.03.26.008714 — neuroscience — Posted on 2020-08-07
3275 Development and characterization of infectious clones of two strains of Usutu virus
Bates, T. A.; Chuong, C.; Hawks, S. A.; Rai, P.; Duggal, N. K.; Weger-Lucarelli, J.
10.1101/2020.08.05.238543 — molecular biology — Posted on 2020-08-07
3276 Infection of human lymphomononuclear cells by SARS-CoV-2
Pontelli, M. C.; Castro, I. A.; Martins, R. B.; Veras, F. P.; La Serra, L.; Nascimento, D. C.; Cardoso, R. S.; Rosales, R.; Lima, T. M.; Souza, J. P.; Caetite, D. B.; Lima, M. H.; Kawahisa, J. T.; Giannini, M. C.; Bonjorno, L. P.; Lopes, M. I.; Batah, S. S.; Siyuan, L.; Assad, R. L.; Almeida, S. C.; Oliveira, F. R.; Benatti, M. N.; Pontes, L. L.; Santana, R. C.; Villar, F. C.; Martins, M. A.; Cunha, T. M.; Calado, R. T.; Alves-Filho, J. C.; Zamboni, D. S.; Fabro, A.; Louzada-Junior, P.; Louzada-Junior, P.; Oliveira, R. D.; Cunha, F. Q.; Arruda, E.
10.1101/2020.07.28.225912 — microbiology — Posted on 2020-08-07
3278 BoLA-DRB3 gene haplotypes show divergence in native Sudanese cattle from Taurine and Zebu breeds
Salim, B.; Takeshima, S.-n.; Nakao, R.; Moustafa, M. A. M.; Ahmed, M.-K. A.; Kambal, S. Y.; Mwacharo, J. M. M.; Giovambattista, G.
10.1101/2020.08.07.241133 — evolutionary biology — Posted on 2020-08-07
3280 Amoeba predation of Cryptococcus neoformans results in pleiotropic changes to traits associated with virulence
Fu, M. S.; Liporagi-Lopes, L. C.; dos Santos Junior, S. R.; Tenor, J.; Perfect, J. R.; Cuomo, C.; Casadevall, A.
10.1101/2020.08.07.241190 — microbiology — Posted on 2020-08-07
3281 Using Plasmodium knowlesi as a model for screening Plasmodium vivax blood-stage malaria vaccine targets reveals new candidates
Ndegwa, D. N.; Hostetler, J. B.; Marin-Menendez, A.; Sanderson, T.; Mwikali, K.; Verzier, L. H.; Coyle, R.; Adjalley, S.; Rayner, J. C.
10.1101/2020.08.07.241125 — microbiology — Posted on 2020-08-07
3282 Effect of oxidized β-carotene-oxygen copolymer compounds on health and performance of pre- and post-weaned pigs
Burton, G. W.; Van Kinh, L.; Riley, W. W.; Nickerson, J. G.; Vinh, D.; Van Phu, N.; Van, N. T.; Huyen, L. T. T.
10.1101/2020.08.07.241174 — immunology — Posted on 2020-08-07
3286 Suppress me if you can: neurofeedback of the readiness potential
Schultze-Kraft, M.; Jonany, V.; Binns, T. S.; Soch, J.; Blankertz, B.; Haynes, J.-D.
10.1101/2020.08.07.241307 — neuroscience — Posted on 2020-08-07
3287 Paranode stability requires UNC5B expression by oligodendrocytes
de Faria, O.; Nakamura, D. S.; Clemot, S.; Kim, D.; Mocanu, M. V.; Pilgram, R.; Bin, J. M.; Wong, E. W.; Shmuel, A.; Sadikot, A.; Ackerman, S. L.; Kennedy, T. E.
10.1101/2020.08.06.234906 — neuroscience — Posted on 2020-08-07
3289 SARS-CoV-2 infection, neuropathogenesis and transmission among deer mice: Implications for reverse zoonosis to New World rodents
Fagre, A.; Lewis, J.; Eckley, M.; Zhan, S.; Rocha, S. M.; Sexton, N. R.; Burke, B.; Geiss, B. J.; Peersen, O.; Kading, R.; Rovnak, J.; Ebel, G. D.; Tjalkens, R. B.; Aboellail, T.; Schountz, T.
10.1101/2020.08.07.241810 — microbiology — Posted on 2020-08-07
3291 Successful introduction of the Colour Test into inexperienced settings
Klaos, K.; Agejeva, A.; Kummik, T.; Laks, S.; Remets, O.; Sasi, S.; Tann, A.; Viiklepp, P.; Altraja, A.
10.1101/2020.08.07.241158 — microbiology — Posted on 2020-08-07
3292 mRNA induced expression of human angiotensin-converting enzyme 2 in mice for the study of the adaptive immune response to severe acute respiratory syndrome coronavirus 2
Hassert, M.; Geerling, E.; Stone, E. T.; Steffen, T. L.; Dickson, A.; Feldman, M. S.; Class, J.; Richner, J. M.; Brien, J. D.; Pinto, A. K.
10.1101/2020.08.07.241877 — immunology — Posted on 2020-08-07
3294 Detecting regulatory elements in high-throughput reporter assays
Kim, Y.-S.; Jonhson, G. D.; Seo, J.; Barrera, A.; Majoros, W. H.; Ochoa, A.; Allen, A. S.; Reddy, T. E.
10.1101/2020.08.07.241901 — bioinformatics — Posted on 2020-08-07
3298 Selfing is the safest sex for Caenorhabditis tropicalis
Noble, L. M.; Yuen, J.; Stevens, L.; Moya, N.; Persaud, R. S.; Moscatelli, M. A.; Jackson, J. L.; Braendle, C.; Andersen, E. C.; Seidel, H. S.; Rockman, M. V.
10.1101/2020.08.07.242032 — evolutionary biology — Posted on 2020-08-07
3304 Generation of tonsil organoids as an ex vivo model for SARS-CoV-2 infection
Kim, H. K.; Kim, H.; Lee, M. K.; Choi, W. H.; Jang, Y.; Shin, J. S.; Park, J.-Y.; Kim, K. H.; Han, H. W.; Kim, M.; Lim, Y. C.; Yoo, J.
10.1101/2020.08.06.239574 — microbiology — Posted on 2020-08-07
3305 The Pancreatic Tumor Microenvironment Buffers Redox Imbalance Imposed by Disrupted Mitochondrial Metabolism
Kerk, S. A.; Lin, L.; Myers, A. L.; Chen, B.; Sajjakulnukit, P.; Robinson, A.; Thurston, G.; Nelson, B. S.; Kemp, S. B.; Steele, N. G.; Hoffman, M. T.; Wen, H.-J.; Long, D.; Ackenhusen, S. E.; Ramos, J.; Gao, X.; Zhang, L.; Andren, A.; Nwosu, Z. C.; Galban, S.; Halbrook, C. J.; Lombard, D. B.; Ying, H.; Crawford, H. C.; Pasca di Magliano, M.; Shah, Y. M.; Lyssiotis, C. A.
10.1101/2020.08.07.238766 — cancer biology — Posted on 2020-08-07
3306 PELP1/SRC-3-dependent regulation of metabolic kinases drives therapy resistant ER+ breast cancer
Truong, T. H.; Benner, E. A.; Hagen, K. M.; Temiz, N. A.; Perez Kerkvliet, C.; Wang, Y.; Pengo, T.; Guillen, K. P.; Welm, B. W.; Telang, S.; Lange, C. A.; Ostrander, J. H.
10.1101/2020.08.07.238550 — cancer biology — Posted on 2020-08-07
3307 Nerve fibers in the Tumor Microenvironment are co-localized with Tertiary Lymphoid Structures
Heij, L. R.; Tan, X.; Kather, J. N.; Niehues, J. M.; Sivakumar, S.; Heussen, N.; van der Kroft, G.; Olde Damink, S. W. M.; Lang, S.; Bednarsch, J.; Aberle, M. R.; Luedde, T.; Gaisa, N.; Liu, D. H. W.; Cleutjens, J. P. M.; Modest, D. P.; Wiltberger, G. J.; Neumann, U. P.
10.1101/2020.08.07.232322 — cancer biology — Posted on 2020-08-07
3309 Ribosome fingerprinting with a solid-state nanopore
Raveendran, M.; Leach, A. R.; Hopes, T. S.; Aspden, J.; Actis, P.
10.1101/2020.08.07.236406 — biophysics — Posted on 2020-08-07
3310 Multivalent interactions between eIF4G1, Pub1 and Pab1 drive the formation of protein condensates
Chaves-Arquero, B.; Martinez-Lumbreras, S.; Sibille, N.; Camero, S.; Bernado, P.; Jimenez, M. A.; Zorrilla, S.; Perez-Canadillas, J. M.
10.1101/2020.08.07.234443 — biophysics — Posted on 2020-08-07
3311 Theory of genetic oscillations with external noisy regulation
Negrete, J.; Lengyel, I. M.; Rohde, L.; Desai, R. A.; Oates, A. C.; Julicher, F.
10.1101/2020.08.07.241042 — biophysics — Posted on 2020-08-07
3312 Single-molecule studies of conformational states and dynamics in the ABC importer OpuA
Tassis, K.; Vietrov, R.; Koning, M. d.; de Boer, M.; Gouridis, G.; Cordes, T.
10.1101/2020.08.07.241463 — biophysics — Posted on 2020-08-07
3318 BrumiR: A toolkit for de novo discovery of microRNAs from sRNA-seq data.
Moraga, C.; Sanchez, E.; Galvao Ferrarini, M.; Gutierrez, R. A.; Vidal, E. A.; Sagot, M.-F.
10.1101/2020.08.07.240689 — bioinformatics — Posted on 2020-08-07
3320 DNA-based nanocarriers to enhance the optoacoustic contrast of tumors in vivo
Joseph, J.; Baumann, K. N.; Postigo, A.; Bollepalli, L.; Bohndiek, S. E.; Hernandez-Ainsa, S.
10.1101/2020.08.07.235705 — bioengineering — Posted on 2020-08-07
3323 Genomic investigation of a suspected multi-drug resistant Klebsiella pneumoniae outbreak in a neonatal care unit in sub-Saharan Africa
Cornick, J. E.; Musicha, P.; Peno, C.; Saeger, E.; Iroh-Tam, P.-Y.; Bennett, A.; Kennedy, N.; Feasey, N.; Heniz, E.; Cain, A. K.
10.1101/2020.08.06.236117 — genomics — Posted on 2020-08-07
3324 Genomic evolutionary analysis in R with geaR.
Ward, C. M.; Ludington, A. J.; Breen, J.; Baxter, S. W.
10.1101/2020.08.06.240754 — genomics — Posted on 2020-08-07
3326 Genome Diversity in Ukraine
Oleksyk, T. K.; Wolfsberger, W. W.; Weber, A.; Shchubelka, K.; Oleksyk, O. T.; Levchuk, O.; Patrus, A.; Lazar, N.; Castro-Marquez, S. O.; Boldyzhar, P.; Urbanovych, A.; Stakhovska, V.; Malyar, K.; Chervyakova, S.; Podoroha, O.; Kovalchuk, N.; Hasynets, Y.; Rodriguez-Flores, J. L.; Medley, S.; Battistuzzi, F. U.; Liu, R.; Hou, Y.; Chen, S.; Yang, H.; Yeager, M.; Dean, M.; Mills, R. E.; Smolanka, V.
10.1101/2020.08.07.238329 — genomics — Posted on 2020-08-07
3330 New insights of zoogeographical distribution of Himalayan goral (Naemorhedus goral) from Indian Himalayan Region
Joshi, B. D.; Singh, V. K.; Singh, H.; Singh, A.; Singh, S. K.; Chandra, K.; Sharma, L. K.; Thakur, M.
10.1101/2020.08.05.239087 — genetics — Posted on 2020-08-07
3334 Hearing impairment due to Mir183/96/182 mutations suggests both loss and gain of function effects
Lewis, M. A.; Di Domenico, F.; Ingham, N. J.; Prosser, H. M.; Steel, K. P.
10.1101/579003 — genetics — Posted on 2020-08-07
3336 Polyandry and senescence shape egg size variation in a precocial bird.
Falcao Rodrigues, L.; Hertel, A. G.; Cruz Lopez, M.; Gonzalez-Medina, E.; Schroeder, J.; Küpper, C.; Eberhart-Phillips, L. J.
10.1101/2020.08.07.240150 — evolutionary biology — Posted on 2020-08-07
3337 Improved reference genome uncovers novel sex-linked regions in the guppy (Poecilia reticulata)
Fraser, B. A.; Whiting, J. R.; Paris, J. R.; Weadick, C. J.; Parsons, P. J.; Charlesworth, D.; Bergero, R.; Bemm, F.; Hoffmann, M.; Kottler, V. A.; Liu, C.; Dreyer, C.; Weigel, D.
10.1101/2020.08.07.240986 — evolutionary biology — Posted on 2020-08-07
3345 Epigenetic change induced by in utero dietary challenge provokes phenotypic variability across multiple generations of mice
Van de Pette, M.; Galvao, A.; Millership, S. J.; To, W.; Dimond, A.; Prodani, C.; McNamara, G.; Bruno, L.; Sardini, A.; Webster, Z.; McGinty, J.; French, P. M.; Uren, A.; Castillo-Fernandez, J.; John, R. M.; Ferguson-Smith, A.; Merkenschlager, M.; Kelsey, G. D.; Fisher, A. G.
10.1101/2020.08.07.241034 — developmental biology — Posted on 2020-08-07
3346 Impaired Fetal Lung Development can be Rescued by Administration of Extracellular Vesicles Derived from Amniotic Fluid Stem Cells
Antounians, L.; Catania, V. D.; Montalva, L.; Liu, B. D.; Hou, H.; Chan, C.; Matei, A. C.; Tzanetakis, A.; Li, B.; Lopes Figueira, R.; Miura da Costa, K.; Wong, A. P.; Mitchell, R.; David, A. L.; Patel, K.; De Coppi, P.; Sbragia Neto, L.; Wilson, M. D.; Rossant, J.; Zani, A.
10.1101/2020.08.07.240408 — developmental biology — Posted on 2020-08-07
3348 Specification and epigenetic resetting of the pig germline exhibit conservation with the human lineage
Zhu, Q.; Sang, F.; Withey, S.; Tang, W.; Dietmann, S.; Klisch, D.; Ramos-Ibeas, P.; Zhang, H.; Requena, C. E.; Hajkova, P.; Loose, M. W.; Surani, A.; Alberio, R.
10.1101/2020.08.07.241075 — developmental biology — Posted on 2020-08-07
3349 Diploid hepatocytes drive physiological liver renewal in adult humans
Heinke, P.; Rost, F.; Rode, J.; Welsch, T.; Alkass, K.; Feddema, J.; Salehpour, M.; Possnert, G.; Druid, H.; Brusch, L.; Bergmann, O.
10.1101/2020.08.07.230086 — cell biology — Posted on 2020-08-07
3350 In situ architecture of neuronal alpha-Synuclein inclusions
Trinkaus, V. A.; Riera-Tur, I.; Martinez-Sanchez, A.; Baeuerlein, F. J. B.; Guo, Q.; Arzberger, T.; Baumeister, W.; Dudanova, I.; Hipp, M. S.; Hartl, F. U.; Fernandez-Busnadiego, R.
10.1101/2020.08.07.234138 — cell biology — Posted on 2020-08-07
3351 Human muscle stem cells are refractory to aging
Novak, J. S.; Mazala, D.; Nearing, M.; Habib, N. F.; Dickson, T.; Ioffe, O. B.; Harris, B. T.; Fidelia-Lambert, M. N.; Rossi, C. T.; Ashley Hill, D.; Wagner, K. R.; Hoffman, E. P.; Partridge, T. A.
10.1101/2020.08.07.238477 — cell biology — Posted on 2020-08-07
3352 Bioorthogonal red and far-red fluorogenic probes for wash-free live-cell and super-resolution microscopy
Werther, P.; Yserentant, K.; Braun, F.; Grussmayer, K. S.; Navikas, V.; Yu, M.; Zhang, Z.; Ziegler, M. J.; Mayer, C.; Gralak, A. J.; Busch, M.; Chi, W.; Rominger, F.; Radenovic, A.; Liu, X.; Lemke, E. A.; Buckup, T.; Herten, D.-P.; Wombacher, R.
10.1101/2020.08.07.241687 — cell biology — Posted on 2020-08-07
3354 Decreased alertness reconfigures cognitive control networks
Canales-Johnson, A.; Beerendonk, L.; Blain, S.; Kitaoka, S.; Ezquerro-Nassar, A.; Nuiten, S.; Fahrenfort, J.; Gaal, S. v.; Bekinschtein, T. A.
10.1101/831727 — neuroscience — Posted on 2020-08-07
3355 Synchronized eye movements predict test scores in online video education
Madsen, J.; Julio, S. U.; Gucik, P. J.; Steinberg, R.; Parra, L. C.
10.1101/809558 — neuroscience — Posted on 2020-08-07
3358 KANSL1 Deficiency Causes Neuronal Dysfunction by Oxidative Stress-Induced Autophagy
Linda, K.; Lewerissa, E.; Verboven, A. H. A.; Gabriele, M.; Frega, M.; Klein Gunnewiek, T. M.; Devilee, L.; Ulferts, E.; Oudakker, A.; Schoenmaker, C.; van Bokhoven, H.; Schubert, D.; Testa, G.; Koolen, D.; de Vries, B. B. A.; Nadif Kasri, N.
10.1101/2020.08.07.241257 — neuroscience — Posted on 2020-08-07
3359 Extrasynaptic volume transmission: A novel route for neuropeptide signaling in nematodes
Atkinson, L. E.; Liu, Y.; McKay, F.; Vandewyer, E.; Viau, C.; Irvine, A.; Rosa, B. A.; Li, Z.; Marks, N. J.; Maule, A. G.; Mitreva, M.; Beets, I.; Li, L. E.; Mousley, A.
10.1101/2020.08.07.240440 — neuroscience — Posted on 2020-08-07
3361 Hidden population modes in social brain morphology: Its parts are more than its sum
Kiesow, H.; Spreng, R. N.; Holmes, A. J.; Chakravarty, M. M.; Marquand, A. F.; Yeo, B. T. T.; Bzdok, D.
10.1101/2020.08.07.241497 — neuroscience — Posted on 2020-08-07
3363 Body mass variations relate to fractionated functional brain hierarchies
Park, B.-y.; Park, H.; Morys, F.; Kim, M.; Byeon, K.; Lee, H.; Kim, S.-H.; Valk, S.; Dagher, A.; Bernhardt, B.
10.1101/2020.08.07.241794 — neuroscience — Posted on 2020-08-07
3365 Neural circuit mechanisms of sexual receptivity in Drosophila females
Wang, K.; Wang, F.; Forknall, N.; Yang, T.; Patrick, C. M.; Parekh, R.; Dickson, B.
10.1101/2020.08.07.241919 — neuroscience — Posted on 2020-08-07
3366 SETD1B controls cognitive function via cell type specific regulation of neuronal identity genes
Fischer, A.; Michurina, A.; Sakib, M. S.; Kerimoglu, C.; Krüger, D. M.; Kaurani, L.; Islam, R.; Centeno, T. P.; Cha, J.; Xu, X.; Zeisberg, E.; Kranz, A.; Stewart, F.
10.1101/2020.08.07.240853 — neuroscience — Posted on 2020-08-07
3368 Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors
Osipiuk, J.; Azizi, S.-A.; Dvorkin, S.; Endres, M.; Jedrzejczak, R.; Jones, K. A.; Kang, S.; Kathayat, R. S.; Kim, Y.; Lisnyak, V. G.; Maki, S. L.; Nicolaescu, V.; Taylor, C. A.; Tesar, C.; Zhang, Y.-A.; Zhou, Z.; Randall, G.; Michalska, K.; Snyder, S. A.; Dickinson, B. C.; Joachimiak, A.
10.1101/2020.08.06.240192 — molecular biology — Posted on 2020-08-07
3369 Birnavirus Ribonucleoprotein Assembly
Busnadiego, I.; Martin, M. T.; Ferrero, D.; Millan de la Blanca, M. G.; Brotp, L.; Diaz-Beneitez, E.; Fuentes, D.; Rodriguez, D.; Verdaguer, N.; Kremer, L.; Rodriguez, J. F.
10.1101/2020.08.06.240028 — microbiology — Posted on 2020-08-07
3374 Cellular barcoding of Toxoplasma reveals permissive host brain colonization
Wincott, C. J.; Sritharan, G.; Bunyan, M.; Alves, E.; Benns, H. J.; Frickel, E. M.; Ewald, S. E.; Child, M. A.
10.1101/2020.08.06.239822 — microbiology — Posted on 2020-08-07
3378 Rhizobium leguminosarum symbiovar viciae strains are natural wheat endophytes and can stimulate root development and colonization by arbuscular mycorrhizal fungi
Bartoli, C.; Boivin, S.; Marchetti, M.; Gris, C.; Gasciolli, V.; Gaston, M.; Auriac, M.-C.; Cottret, L.; Carlier, A.; Masson-Boivin, C.; Lepetit, M.; Lefebvre, B.
10.1101/2020.08.07.241844 — microbiology — Posted on 2020-08-07
3379 Innovation in NLR and TLR sensing drives the MHC-II free Atlantic cod immune system.
Jin, X.; Morro, B.; Torresen, O. K.; Moiche, V.; Solbakken, M. H.; Jakobsen, K. S.; Jentoft, S.; MacKenzie, S.
10.1101/2020.08.07.241067 — immunology — Posted on 2020-08-07
3380 Macrophages promote endothelial-to-mesenchymal transition via MT1-MMP/TGFβ after myocardial infarction
Alonso-Herranz, L.; Sahun-Espanol, A.; Gonzalo, P.; Gkontra, P.; Nunez, V.; Cedenilla, M.; Villalba-Orero, M.; Inserte, J.; Clemente, C.; Garcia-Dorado, D.; Arroyo, A. G.; Ricote, M.
10.1101/2020.08.07.240820 — immunology — Posted on 2020-08-07
3382 Engineered sex distortion in the global agricultural pest Ceratitis capitata
Meccariello, A.; Krsticevic, F.; Colonna, R.; Del Corsano, G.; Fasulo, B.; Papathanos, P. A.; Windbichler, N.
10.1101/2020.08.07.240226 — synthetic biology — Posted on 2020-08-07
3384 The Vagus Nerve Mediates the Physiological but not Pharmacological Effects of PYY3-36 on Food Intake
Martin Alonso, A.; Cork, S. C.; Ma, Y.; Arnold, M.; Herzog, H.; Bloom, S. R.; Distaso, W.; Murphy, K.; Salem, V.
10.1101/2020.08.07.241851 — physiology — Posted on 2020-08-07
3385 Interstitial spaces are continuous across tissue and organ boundaries in humans
Cenaj, O.; Allison, D. H. R.; Imam, R.; Zeck, B.; Drohan, L. M.; Chiriboga, L.; Llewellyn, J.; Liu, C. Z.; Park, Y. N.; Wells, R. G.; Theise, N. D.
10.1101/2020.08.07.239806 — pathology — Posted on 2020-08-07
3386 Anatomy and activity patterns in a multifunctional motor neuron and its surrounding circuitsGOOGLE
Ashaber, M.; Tomina, Y.; Kassraian-Fard, P.; Bushong, E. A.; Kristan, W. B.; Ellisman, M. H.; Wagenaar, D. A.
10.1101/2020.03.09.984013 — neuroscience — Posted on 2020-08-07
3388 Alveolitis in severe SARS-CoV-2 pneumonia is driven by self-sustaining circuits between infected alveolar macrophages and T cells
Grant, R. A.; Morales-Nebreda, L.; Markov, N. S.; Swaminathan, S.; Guzman, E. R.; Abbott, D. A.; Donnelly, H. K.; Donayre, A.; Goldberg, I. A.; Klug, Z. M.; Borkowski, N.; Lu, Z.; Kihshen, H.; Politanska, Y.; Sichizya, L.; Kang, M.; Shilatifard, A.; Qi, C.; Argento, A. C.; Kruser, J. M.; Malsin, E. S.; Pickens, C. O.; Smith, S.; Walter, J. M.; Pawlowski, A. E.; Schneider, D.; Nannapaneni, P.; Abdala-Valencia, H.; Bharat, A.; Gottardi, C. J.; Budinger, G. S.; Misharin, A. V.; Singer, B. D.; Wunderink, R. G.; The NU SCRIPT Study Investigators,
10.1101/2020.08.05.238188 — immunology — Posted on 2020-08-07
3389 Proteins and Ions Compete for Membrane Interaction: the case of Lactadherin
De Lio, A. M.; Paul, D.; Jain, R.; Morrissey, J. H.; Pogorelov, T. V.
10.1101/2020.04.03.023838 — biophysics — Posted on 2020-08-07
3392 SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade
Romero, O. A.; Villarrubi, A.; Alburquerque-Bejar, J. J.; Gomez, A.; Andrade, A.; Trastulli, D.; Pros, E.; Verdura, S.; Farre, L.; Martin-Tejera, J. F.; Llabata, P.; Oaknin, A.; Saigi, M.; Piulats, J. M.; Matias-Guiu, X.; Medina, P. P.; Vidal, A.; Villanueva, A.; Sanchez-Cespedes, M.
10.1101/2020.08.07.241232 — cancer biology — Posted on 2020-08-07
3394 Epicardial slices: a 3D organotypic model for the study of epicardial activation and differentiation
Maselli, D.; Matos, R. S.; Johnson, R. D.; Chiappini, C.; Camelliti, P.; Campagnolo, P.
10.1101/2020.08.07.219931 — bioengineering — Posted on 2020-08-07
3395 Structural and functional brain parameters related to cognitive performance across development: Replication and extension of the parieto-frontal integration theory in a single sample.
Gur, R. C.; Butler, E. R.; Moore, T. M.; Rosen, A. F. G.; Ruparel, K.; Satterthwaite, T. D.; Roalf, D. R.; Gennatas, E. D.; Bilker, W. B.; Shinohara, R. T.; Port, A.; Elliott, M. A.; Verma, R.; Davatzikos, C.; Wolf, D. H.; Detre, J. A.; Gur, R. E.
10.1101/659193 — neuroscience — Posted on 2020-08-07
3396 Non-Toxic Virucidal Macromolecules Show High Efficacy Against Influenza Virus Ex Vivo and In Vivo
Kocabiyik, O.; Cagno, V.; Jacob Silva, P.; Zhu, Y.; Sedano, L.; Bhide, Y.; Mettier, J.; Medaglia, C.; Da Costa, B.; Constant, S.; Huang, S.; Kaiser, L.; Hinrichs, W.; Huckriede, A.; Le Goffic, R.; Tapparel, C.; Stellacci, F.
10.1101/2020.03.18.996678 — microbiology — Posted on 2020-08-07
3400 Not out of the box: phylogeny of the broadly sampled Buxaceae
Shipunov, A.; Lee, H. J.; Choi, J.; Pay, K.; DeSpiegelaire, S.; Floden, A.
10.1101/2020.08.03.235267 — plant biology — Posted on 2020-08-07
3402 Long vs short-term synaptic learning rules after optogenetic spike-timing-dependent plasticity
Anisimova, M.; van Bommel, B.; Wiegert, J. S.; Mikhaylova, M.; Oertner, T. G.; Gee, C. E.
10.1101/863365 — neuroscience — Posted on 2020-08-07
3403 Emotion suppression failures are associated with local increases in sleep-like activity
Avvenuti, G.; Bertelloni, D.; Lettieri, G.; Ricciardi, E.; Cecchetti, L.; Pietrini, P.; Bernardi, G.
10.1101/2020.08.04.235978 — neuroscience — Posted on 2020-08-07
3405 Development and characterization of infectious clones of two strains of Usutu virus
Bates, T. A.; Chuong, C.; Hawks, S. A.; Rai, P.; Salgado, R. M.; Duggal, N. K.; Weger-Lucarelli, J. A.
10.1101/2020.08.05.238543 — molecular biology — Posted on 2020-08-07
3406 The genome of a persistent giant algal virus encodes an unprecedented number of genes involved in energy metabolism
Blanc-Mathieu, R.; Dahle, H.; Hofgaard, A.; Brandt, D.; Kalinowski, J.; Ogata, H.; Sandaa, R.-A.
10.1101/2020.07.30.228163 — microbiology — Posted on 2020-08-07
3407 Combined analysis of single cell RNA-Seq and ATAC-Seq data reveals putative regulatory toggles operating in native and iPS-derived retina.
Georges, A.; Takeda, H.; Lavergne, A.; Mandai, M.; Lepiemme, F.; Karim, L.; Demeulenaere, L.; Schyns, M.; Nguyen, L.; Rakic, J.-M.; Takahashi, M.; Georges, M.
10.1101/2020.03.02.972497 — developmental biology — Posted on 2020-08-07
3409 Liver x receptor alpha drives chemoresistance in response to side-chain hydroxycholesterols in triple negative breast cancer
Hutchinson, S. A.; Websdale, A.; Lianto, P.; Cioccoloni, G.; Roberg-Larsen, H.; Kim, B.; Rose, A.; Soteriou, C.; Wastall, L. M.; Williams, B.; Henn, M.; Chen, J. J.; Ma, L.; Moore, J. B.; Nelson, E. R.; Hughes, T. A.; Thorne, J. L.
10.1101/2020.08.04.235697 — cancer biology — Posted on 2020-08-07
3412 Denisovan introgression has shaped the immune system of present-day Papuans
Vespasiani, D. M.; Jacobs, G. S.; Brucato, N.; Cox, M. P.; Gallego Romero, I.
10.1101/2020.07.09.196444 — genomics — Posted on 2020-08-07
3413 High neutralizing potency of swine glyco-humanized polyclonal antibodies against SARS-CoV-2
Vanhove, B.; Duvaux, O.; Rousse, J.; Royer, P.-J.; Evanno, G.; Ciron, C.; Lheriteau, E.; Vacher, L.; Gervois, N.; Oger, R.; Jacques, Y.; Conchon, S.; Salama, A.; Duchi, R.; Lagutina, I.; Perota, A.; Delahaut, P.; Ledure, M.; Paulus, M.; So, R.; Mok, C. K. P.; Bruzzone, R.; Bouillet, M.; Brouard, S.; Cozzi, E.; Galli, C.; Blanchard, D.; Bach, J.-M.; Soulillou, J.-P.
10.1101/2020.07.25.217158 — immunology — Posted on 2020-08-07
3416 Reduced placental transfer of antibodies against microbial and vaccine antigens in HIV-infected women in Mozambique
Alonso, S.; Vidal, M.; Ruiz-Olalla, G.; Gonzalez, R.; Manaca, M. N.; Jairoce, C.; Vazquez-Santiago, M.; Balcells, R.; Vala, A.; Ruperez, M.; Cistero, P.; Fuente-Soro, L.; Cova, M.; Angov, E.; Nhacolo, A.; Sevene, E.; Aponte, J. J.; Macete, E.; Aguilar, R.; Mayor, A.; Menendez Santos, C.; Dobano, C.; Moncunill, G.
10.1101/2020.08.05.237503 — immunology — Posted on 2020-08-07
3418 White Matter Disruption in Pediatric Traumatic Brain Injury: Results from ENIGMA Pediatric msTBI
Dennis, E. L.; Caeyenberghs, K.; Hoskinson, K. R.; Merkley, T. L.; Suskauer, S. J.; Asarnow, R. F.; Babikian, T.; Bartnik-Olson, B.; Bickart, K.; Bigler, E. D.; Ewing-Cobbs, L.; Figaji, A.; Giza, C. C.; Hunsaker-Goodrich, N. J.; Hodges, C. B.; Hovenden, E. S.; Irimia, A.; Königs, M.; Levin, H. S.; Lindsey, H. M.; Max, J. E.; Newsome, M. R.; Olsen, A.; Ryan, N. P.; Schmidt, A. T.; Spruiell, M. S.; Wade, B. S.; Ware, A. L.; Watson, C. G.; Wheeler, A. L.; Yeates, K. O.; Zielinski, B. A.; Kochunov, P.; Jahanshad, N.; Thompson, P. M.; Tate, D. F.; Wilde, E. A.
10.1101/2020.08.06.237271 — neuroscience — Posted on 2020-08-07
3419 The R1-weighted connectome: complementing brain networks with a myelin-sensitive measure
Boshkovski, T.; Kocarev, L.; Cohen-Adad, J.; Misic, B.; Lehericy, S.; Stikov, N.; Mancini, M.
10.1101/2020.08.06.237941 — neuroscience — Posted on 2020-08-07
3420 The longitudinal stability of fMRI activation during reward processing in adolescents and young adults
Baranger, D. A.; Lindenmuth, M.; Nance, M.; Guyer, A. E.; Keenan, K.; Hipwell, A. E.; Shaw, D. S.; Forbes, E. E.
10.1101/2020.08.06.236596 — neuroscience — Posted on 2020-08-07
3421 Optogenetic delivery of trophic signals in a genetic model of Parkinson's disease
Ingles-Prieto, A.; Furthmann, N.; Crossman, S.; Hoyer, N.; Petersen, M.; Zheden, V.; Biebl, J.; Reichhart, E.; Gyoergy, A.; Siekhaus, D.; Soba, P.; Winklhofer, K. F.; Janovjak, H.
10.1101/2020.08.06.238816 — neuroscience — Posted on 2020-08-07
3427 Identification of the keystone species in non-alcoholic fatty liver disease by causal inference and dynamic intervention modeling
Wu, D.; Jiao, N.; Zhu, R.; Zhang, Y.; Gao, W.; Fang, S.; Li, Y.; Cheng, S.; Tian, C.; Lan, P.; Loomba, R.; Zhu, L.
10.1101/2020.08.06.240655 — bioinformatics — Posted on 2020-08-07
3428 Newly discovered tilapia cichlid fish biodiversity threatened by hybridization with non-native species
Blackwell, T.; Ford, A. G. P.; Ciezarek, A. G.; Bradbeer, S. J.; Gracida Juarez, C. A.; Ngatunga, B. P.; Shechonge, A. H.; Tamatamah, R.; Etherington, G. J.; Haerty, W.; Di Palma, F.; Turner, G. F.; Genner, M. J.
10.1101/2020.08.06.240002 — zoology — Posted on 2020-08-07
3430 Decoding Multivoxel Representations of Affective Scenes in Retinotopic Visual Cortex
Bo, K.; Yin, S.; Liu, Y.; Hu, Z.; Meyyapan, S.; Kim, S.; Andreas, K.; Ding, M.
10.1101/2020.08.06.239764 — neuroscience — Posted on 2020-08-07
3431 Ubiquitous selfish toxin-antidote elements in Caenorhabditis species
Ben-David, E.; Pliota, P.; Widen, S. A.; Koreshova, A.; Lemus-Vergara, T.; Verpukhovskiy, P.; Mandali, S.; Braendle, C.; Burga, A.; Kruglyak, L.
10.1101/2020.08.06.240564 — genomics — Posted on 2020-08-07
3432 Genome wide efficiency profiling reveals modulation of maintenance and de novo methylation by Tets
Giehr, P.; Kyriakopoulos, C.; Karl Nordström, K.; Salhab, A.; Müller, F.; von Meyenn, F.; Ficz, G.; Reik, W.; Wolf, V.; Walter, J.
10.1101/2020.08.06.236307 — genomics — Posted on 2020-08-07
3437 Genomic signals of admixture and reinforcement between two closely related species of European sepsid flies
Giesen, A.; Blanckenhorn, W. U.; Schaefer, M. A.; Shimizu, K. K.; Shimizu-Inatsugi, R.; Misof, B.; Niehuis, O.; Podsiadlowski, L.; Lischer, H. E. L.; Aeschbacher, S.; Kapun, M.
10.1101/2020.03.11.985903 — evolutionary biology — Posted on 2020-08-07
3440 A unified view of neighbour cell engagement during apoptotic cell extrusion.
Duszyc, K.; Gomez, G.; Lagendijk, A.; Yau, M.-K.; Gliddon, B.; Hall, T.; Verma, S.; Hogan, B.; Pitson, S.; Fairlie, D.; Parton, R.; Yap, A.
10.1101/2020.08.06.240671 — cell biology — Posted on 2020-08-06
3441 Gluconeogenic Enzyme PCK1 Deficiency Is Critical for CHK2 O-GlcNAcylation and Hepatocellular Carcinoma Growth upon Glucose Deprivation
Xiang, J.; Chen, C.; Liu, R.; Gou, D.; Chang, L.; Deng, H.; Gao, Q.; Zhang, W.; Tuo, L.; Pan, X.; Liang, L.; Xia, J.; Huang, L.; Huang, A.; Wang, K.; Tang, N.
10.1101/2020.08.06.240739 — cancer biology — Posted on 2020-08-06
3443 Bayesian Decoder Models with a Discriminative Observation Process
Rezaei, M. R.; Hadjinicolaou, A. E.; Cash, S. S.; Eden, U.; Yousefi, A.
10.1101/2020.07.11.198564 — bioinformatics — Posted on 2020-08-06
3446 Slow AMPA receptors in hippocampal principal cells
Pampaloni, N. P.; Riva, I.; Carbone, A. L.; Plested, A.
10.1101/2020.08.05.238667 — neuroscience — Posted on 2020-08-06
3447 Neurofeedback fMRI in the motor system elicits bi-directional changes in activity and white-matter structure in the healthy adult human brain
Sampaio-Baptista, C.; Neyedli, H. F.; Sanders, Z.-B.; Diosi, K.; Havard, D.; Huang, Y.; Andersson, J. L. R.; Luehrs, M.; Goebel, R.; Johansen-Berg, H.
10.1101/2020.08.06.234526 — neuroscience — Posted on 2020-08-06
3448 Statistical Pitfalls in Brain Age Analyses
Butler, E. R.; Chen, A. A.; Ramadan, R.; Ruparel, K.; Moore, T. M.; Zhang, F.; Shou, H.; Gur, R. C.; Nichols, T. E.; Shinohara, R. T.
10.1101/2020.06.21.163741 — neuroscience — Posted on 2020-08-06
3450 Single amino acid mutations effect Zika virus replication in vitro and virulence in vivo
Collette, N. K.; Lao, V. K.; Weilhammer, D.; Zingg, B.; Cohen, S. K.; Hwang, M. K.; Coffey, L.; Grady, S.; Zemla, A. K.; Borucki, M. K.
10.1101/2020.08.06.239392 — microbiology — Posted on 2020-08-06
3453 Diversity of sea star-associated densoviruses and transcribed endogenized viral elements of densovirus origin
Jackson, E. W.; Wilhelm, R. C.; Johnson, M. R.; Lutz, H. L.; Danforth, I.; Gaydos, J. K.; Hart, M. H.; Hewson, I. H.
10.1101/2020.08.05.239004 — genomics — Posted on 2020-08-06
3454 Emerging fungal pathogen on an invasive grass differentially affects native species
Kendig, A.; Svahnstrom, V. J.; Adhikari, A.; Harmon, P. F.; Flory, S. L.
10.1101/2020.08.06.239319 — ecology — Posted on 2020-08-06
3455 Peptide Antidotes to SARS-CoV-2 (COVID-19)
Watson, A.; Ferreira, L. M. R.; Hwang, P.; Xu, J.; Stroud, R.
10.1101/2020.08.06.238915 — bioengineering — Posted on 2020-08-06
3457 Hematopoietic stem cells self-renew symmetrically or gradually proceed to differentiation
Hofer, T.; Rodewald, H.-R.; Busch, K.; Fanti, A.-K.; Greco, A.; Wang, X.; Zhang, Q.; Barile, M.; Oguro, H.; Morrison, S. J.
10.1101/2020.08.06.239186 — systems biology — Posted on 2020-08-06
3460 SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response
Huang, J.; Hume, A. J.; Abo, K. M.; Werder, R. B.; Villacorta-Martin, C.; Alysandratos, K. D.; Beermann, M. L.; Simone-Roach, C.; Olejnik, J.; Suder, E.; Bullitt, E.; Hinds, A.; Sharma, A.; Bosmann, M.; Wang, R.; Hawkins, F.; Burks, E. J.; Saeed, M.; Wilson, A. A.; Mühlberger, E.; Kotton, D. N.
10.1101/2020.06.30.175695 — molecular biology — Posted on 2020-08-06
3461 Actinobacteria challenge the paradigm: a unique protein architecture for a well-known central metabolic complex
Bruch, E. M.; Vilela, P.; Lexa-Sapart, N.; Yang, L.; Raynal, B.; Alzari, P. M.; Bellinzoni, M.
10.1101/2020.07.24.212647 — microbiology — Posted on 2020-08-06
3462 A highly attenuated vaccinia virus strain LC16m8-based vaccine for severe fever with thrombocytopenia syndrome
Yoshikawa, T.; Taniguchi, S.; Kato, H.; Iwata-Yoshikawa, N.; Tani, H.; Kurosu, T.; Fujii, H.; Omura, N.; Shibamura, M.; Watanabe, S.; Egawa, K.; Inagaki, T.; Sugimoto, S.; Phanthanawiboon, S.; Harada, S.; Yamada, S.; Fukushi, S.; Morikawa, S.; Nagata, N.; Shimojima, M.; Saijo, M.
10.1101/2020.08.06.239368 — microbiology — Posted on 2020-08-06
3463 A multifaceted cellular damage repair and prevention pathway promotes high level tolerance to β-lactam antibiotics
Shin, J.-H.; Choe, D.; Ransegnola, B.; Hong, H.-R.; Onyekwere, I.; Cross, T.; Shi, Q.; Cho, B.-K.; Westblade, L. F.; Brito, I.; Doerr, T.
10.1101/777375 — microbiology — Posted on 2020-08-06
3465 Activation of p21 limits acute lung injury and induces early senescence after acid aspiration and mechanical ventilation
Blazquez-Prieto, J.; Huidobro, C.; Lopez-Alonso, I.; Amado-Rodriguez, L.; Martin-Vicente, P.; Lopez-Martinez, C.; Crespo, I.; Pantoja, C.; Fernandez-Marcos, P. J.; Serrano, M.; Sznajder, J. I.; Albaiceta, G. M.
10.1101/2020.03.24.005983 — cell biology — Posted on 2020-08-06
3466 Myofiber stretch induces tensile and shear deformation of muscle stem cells in their native niche
Haroon, M.; Klein-Nulend, J.; Bakker, A. D.; Jin, J.; Offringa, C.; Le Grand, F.; Giordani, L.; Liu, K. J.; Knight, R. D.; Jaspers, R. T.
10.1101/2020.01.14.902510 — cell biology — Posted on 2020-08-06
3467 Cancer associated talin point mutations disorganise cell adhesion and migration
Azizi, L.; Cowell, A.; Mykuliak, V. V.; Goult, B. T.; Turkki, P.; Hytonen, V. P.
10.1101/2020.03.25.008193 — cancer biology — Posted on 2020-08-06
3468 Exometabolomic analysis of decidualizing human endometrial stromal and perivascular cells
Harden, S. L.; Zhou, J.; Diniz-da-Costa, M.; Lucas, E. S.; Cui, L.; Murakami, K.; Fang, J.; Chen, Q.; Brosens, J. J.; Lee, Y. H.
10.1101/2020.08.06.221119 — systems biology — Posted on 2020-08-06
3469 Feature Extraction Approaches for Biological Sequences: A Comparative Study of Mathematical Models
Bonidia, R. P.; Sampaio, L. D. H.; Domingues, D. S.; Paschoal, A. R.; Lopes, F. M.; de Carvalho, A. C. P. d. L. F.; Sanches, D. S.
10.1101/2020.06.08.140368 — bioinformatics — Posted on 2020-08-06
3473 High-resolution mapping of Rym14Hb, a wild relative resistance gene to barley yellow mosaic disease
Pidon, H.; Wendler, N.; Habekuss, A.; Maasberg, A.; Ruge-Wehling, B.; Perovic, D.; Ordon, F.; Stein, N.
10.1101/2020.08.06.239145 — plant biology — Posted on 2020-08-06
3474 Opposing functions of the plant TOPLESS gene family during SNC1-mediated autoimmunity
Garner, C. M.; Spears, B. J.; Su, J.; Cseke, L.; Smith, S. N.; Rogan, C. J.; Gassmann, W.
10.1101/2020.08.06.239301 — plant biology — Posted on 2020-08-06
3476 Lamin-related congenital muscular dystrophy alters mechanical signaling and skeletal muscle growth
Owens, D. J.; Messeant, J.; Moog, S.; Viggars, M.; Ferry, A.; Mamchaoui, K.; Lacene, E.; Romero, N.; Brull, A.; Bonne, G.; Butler-Bowne, G. S.; Coirault, C.
10.1101/2020.08.06.239210 — physiology — Posted on 2020-08-06
3477 Diversified regulation of circadian clock gene expression following whole genome duplication
West, A. C.; Iversen, M.; Jorgensen, E. H.; Sandve, S. R.; Hazlerigg, D. G.; Wood, S. H.
10.1101/2020.03.22.002162 — physiology — Posted on 2020-08-06
3481 Common synaptic phenotypes arising from diverse mutations in the human NMDA receptor subunit GluN2A
Elmasri, M.; Hunter, D.; Winchester, G.; Aziz, W.; Bates, E.; Moolenaar Van Der Does, D.; Karachaliou, E.; Sakimura, K.; Penn, A. C.
10.1101/2020.08.06.240010 — neuroscience — Posted on 2020-08-06
3487 Sailing in rough waters: examining volatility of fMRI noise
Leppanen, J.; Stone, H.; Lythgoe, D. J.; Williams, S.; Horvath, B.
10.1101/2020.06.19.161570 — neuroscience — Posted on 2020-08-06
3488 Dendrimer-targeted immunosuppression of microglia reactivity super-accelerates photoreceptor regeneration in the zebrafish retina
Emmerich, K. B.; White, D. T.; Kambhamptati, S. P.; Lee, G. Y.; Fu, T.-M.; Sahoo, A.; Saxena, M. T.; Betzig, E.; Kannan, R. M.; Mumm, J. S.
10.1101/2020.08.05.238352 — neuroscience — Posted on 2020-08-06
3489 Change in social rank and brain dopamine levels: findings from a novel pig model
Cheng, H.; Mohammed, A. M.; Pease, A. P.; Gehrke, J.; Bohart, G.; Burnett, R.; Nader, M. A.; Anthony, J. C.
10.1101/2020.08.06.239780 — neuroscience — Posted on 2020-08-06
3492 Induction of core symptoms of autism spectrum disorders by in vivo CRISPR/Cas9-based gene editing in the brain of adolescent rhesus monkeys
Shihao, W.; Xiao, L.; Dongdong, Q.; Linheng, Z.; Tian-Lin, C.; Zhifang, C.; Binbin, N.; Xiaofeng, R.; Jing, W.; Wenchao, W.; Yingzhou, H.; Yilin, G.; Longbao, L.; Yong, Y.; Xintian, H.; Zilong, Q.
10.1101/2020.08.03.233437 — neuroscience — Posted on 2020-08-06
3493 Chromosomal instability by mutations in a novel specificity factor of the minor spliceosome
de Wolf, B.; Oghabian, A.; Akinyi, M. V.; Hanks, S.; Tromer, E. C.; van Hooff, J.; van Voorthuijsen, L.; van Rooijen, L. E.; Verbeeren, J.; Uijttewaal, E. C. H.; Baltissen, M. P. A.; Yost, S.; Piloquet, P.; Vermeulen, M.; Snel, B.; Isidor, B.; Rahman, N.; Frilander, M. J.; Kops, G. J. P. L.
10.1101/2020.08.06.239418 — molecular biology — Posted on 2020-08-06
3496 Mechanistic Analysis of the Broad Antiretroviral Resistance Conferred by HIV-1 Envelope Glycoprotein Mutations
Hikichi, Y.; Van Duyne, R.; Pham, P.; Groebner, J. L.; Wiegand, A.; Mellors, J. W.; Kearney, M. F.; Freed, E. O.
10.1101/2020.08.06.239350 — microbiology — Posted on 2020-08-06
3500 SNPC-1.3 is a sex-specific transcription factor that drives male piRNA expression in C. elegans
Choi, C. P.; Tay, R. J.; Starostik, M. R.; Feng, S.; Moresco, J. J.; Montgomery, B. E.; Xu, E.; Hammond, M. A.; Schatz, M. C.; Montgomery, T. A.; Yates, J. R.; Jacobsen, S. E.; Kim, J. K.
10.1101/2020.08.06.240200 — developmental biology — Posted on 2020-08-06
3502 De novo synthesis and salvage pathway coordinately regulates polyamine homeostasis and determines T cell proliferation and function.
Wu, R.; Chen, X.; Kang, S.; Wang, T.; Gnanaprakasam, J. R.; Yao, Y.; Liu, L.; Zheng, S.; Fan, G.; Burns, M.; Wang, R.
10.1101/2020.04.29.068759 — cell biology — Posted on 2020-08-06
3503 Data-guided Multi-Map variables for ensemble refinement of molecular movies
Vant, J. W.; Sarkar, D.; Fiorin, G.; Skeel, R. D.; Vermaas, J. V.; Singharoy, A.
10.1101/2020.07.23.217794 — biophysics — Posted on 2020-08-06
3504 Auto-regulatory J-domain interactions control Hsp70 recruitment to the DnaJB8 chaperone
Ryder, B. D.; Matlahov, I.; Bali, S.; Vaquer-Alicea, J.; Van der Wel, P. C. A.; Joachimiak, L. A.
10.1101/2020.01.09.899237 — biochemistry — Posted on 2020-08-06
3506 Prime editing primarily induces undesired outcomes in mice
Aida, T.; Wilde, J. J.; Yang, L.; Hou, Y.; Li, M.; Xu, D.; Lin, J.; Qi, P.; Lu, Z.; Feng, G.
10.1101/2020.08.06.239723 — molecular biology — Posted on 2020-08-06
3508 The human Origin Recognition Complex is essential for pre-RC assembly, mitosis and maintenance of nuclear structure.
Chou, H.-C.; Bhalla, K.; Demerdesh, O. E.; Klingbeil, O.; Hanington, K.; Aganezov, S.; Andrews, P.; Alsudani, H.; Chang, K.; Vakoc, C. R.; Schatz, M. C.; McCombie, W. R.; Stillman, B.
10.1101/2020.08.06.240358 — molecular biology — Posted on 2020-08-06
3509 Clostridioides difficile exploits toxin-mediated inflammation to alter the host nutritional landscape and exclude competitors from the gut microbiota
Fletcher, J. R.; Pike, C. M.; Parsons, R. J.; Rivera, A. M.; Foley, M. H.; McLaren, M. R.; Montgomery, S. A.; Theriot, C. M.
10.1101/2020.08.06.238881 — microbiology — Posted on 2020-08-06
3511 A genome compendium reveals diverse metabolic adaptations of Antarctic soil microorganisms
Ortiz, M.; Leung, P. M.; Shelley, G.; Van Goethem, M. W.; Bay, S. K.; Jordaan, K.; Vikram, S.; Hogg, I. D.; Makhalanyane, T. P.; Chown, S. L.; Grinter, R.; Cowan, D. A.; Greening, C.
10.1101/2020.08.06.239558 — microbiology — Posted on 2020-08-06
3512 Effects of agricultural fungicide use on Aspergillus fumigatus abundance, antifungal susceptibility, and population structure
Barber, A. E.; Riedel, J.; Sae-Ong, T.; Kang, K.; Brabetz, W.; Panagiotou, G.; Deising, H. B.; Kurzai, O.
10.1101/2020.05.26.116616 — microbiology — Posted on 2020-08-06
3518 The N-Glycome regulates the endothelial-to-hematopoietic transition
Kasper, D. M.; Hintzen, J.; Wu, Y.; Ghersi, J.; Mandl, H. K.; Salinas, K.; Armero, W.; He, Z.; Sheng, Y.; Xie, Y.; Heindel, D. W.; Park, E. J.; Sessa, W.; Mahal, L.; Lebrilla, C.; Hirschi, K.; Nicoli, S.
10.1101/602912 — developmental biology — Posted on 2020-08-06
3520 ATP dependent DNA transport within cohesin: Scc2 clamps DNA on top of engaged heads while Scc3 promotes entrapment within the SMC-kleisin ring
Collier, J. E.; Lee, B.-G.; Brunet-Roig, M.; Yatskevich, S.; Petela, N. J.; Metson, J.; Voulgaris, M.; Gonzalez Llamazares, A.; Lowe, J.; Nasmyth, K. A.
10.1101/2020.06.03.132233 — biochemistry — Posted on 2020-08-06
3524 Quantitative lineage analysis identifies a long-term progenitor niche for the hepato-pancreato-biliary organ system
Willnow, D.; Benary, U.; Margineanu, A.; Vignola, M. L.; Pongrac, I. M.; Karimaddini, Z.; Vigilante, A.; Wolf, J.; Spagnoli, F. M.
10.1101/2020.08.06.240176 — developmental biology — Posted on 2020-08-06
3525 Enhanced inflammatory response mediated by parenchymal cells associates with resistance towards mTOR inhibition
Jiao, L.; Eickhoff, R.; Jumpertz, S.; Roth, J.; Erdem, M.; Kroh, A.; Duimel, H.; Lopez Iglesias, C.; Schmeding, M.; Heij, L. R.; Meierhofer, D.; Neumann, U. P.; Cramer, T.
10.1101/2020.08.06.239426 — cancer biology — Posted on 2020-08-06
3527 SVCollector: Optimized sample selection for cost-efficient long-read population sequencing
Ranallo-Benavidez, T. R.; Lemmon, Z. H.; Soyk, S.; Aganezov, S.; Salerno, W. J.; McCoy, R. C.; Lippman, Z. B.; Schatz, M. C.; Sedlazeck, F. J.
10.1101/2020.08.06.240390 — bioinformatics — Posted on 2020-08-06
3528 Similarities and dissimilarities between psychiatric cluster disorders
Smail, M. A.; Wu, X.; Henkel, N. D.; Eby, H. M.; Herman, J. P.; McCullumsmith, R. E.; Shukla, R.
10.1101/2020.08.06.239566 — bioinformatics — Posted on 2020-08-06
3535 A combined pipeline for quantitative analysis of human brain cytoarchitecture
Costantini, I.; Mazzamuto, G.; Roffilli, M.; Castelli, F.; Neri, M.; Lughi, G.; Simonetto, A.; Laurino, A.; Lazzeri, E.; Pesce, L.; Destrieux, C.; Silvestri, L.; Conti, V.; Guerrini, R.; Pavone, F. S.
10.1101/2020.08.06.219444 — neuroscience — Posted on 2020-08-06
3539 Genetic Disruption of WASHC4 Drives Endo-lysosomal Dysfunction and Cognitive-Movement Impairments in Mice and Humans
Courtland, J. L.; Bradshaw, T. W.; Waitt, G.; Soderblom, E. J.; Ho, T.; Rajab, A.; Vancini, R.; Kim, I. H.; Soderling, S.
10.1101/2020.08.06.239517 — cell biology — Posted on 2020-08-06
3540 Molecular motion and tridimensional nanoscale localization of kindlin control integrin activation in focal adhesions
Orre, T.; Karatas, Z.; Kastberger, B.; Cabriel, C.; Boettcher, R. T.; Leveque-Fort, S.; Sibarita, J.-B.; Faessler, R.; Wehrle-Haller, B.; Rossier, O.; Giannone, G.
10.1101/2020.08.06.239731 — cell biology — Posted on 2020-08-06
3541 STAG2 loss-of-function affects short-range genomic contacts and modulates urothelial differentiation in bladder cancer cells
Richart Gines, L.; Lapi, E.; Pancaldi, V.; Cuenca, M.; Castillo de Santa Pau, E.; Madrid, M.; Neyret-Kahn, H.; Radvanyi, F.; Rodriguez, J.; Cuartero, Y.; Serra, F.; Le Dily, F.; Valencia, A.; Marti-Renom, M. A.; Real, F. X.
10.1101/2020.08.06.240457 — cancer biology — Posted on 2020-08-06
3545 Epigenetic Interaction between UTX and DNMT1 Regulates Diet-Induced Myogenic Remodeling in Brown Fat
Li, F.; Jing, J.; Movahed, M.; Cui, X.; Cao, Q.; Wu, R.; Chen, Z.; Yu, L.; Pan, Y.; Shi, H.; Xue, B.; Shi, H.
10.1101/2020.08.05.238923 — physiology — Posted on 2020-08-06
3547 Molecular markers characterization determining cell fate specification in an adult neurogenesis model of Alzheimer's disease
Blanco, I.; Cabello, J.; Urdanoz-Casado, A.; Acha, B.; Gomez-Orte, E. M.; Roldan, M.; Perez-Rodriguez, D. R.; Mendioroz, M.
10.1101/2020.08.06.239111 — neuroscience — Posted on 2020-08-06
3548 Morphologically constrained modeling of spinous inhibition in the somato-sensory cortex
Gemin, O.; Serna, P.; Assendorp, N.; Fossati, M.; Rostaing, P.; Triller, A.; Charrier, C.
10.1101/2020.08.06.230722 — neuroscience — Posted on 2020-08-06
3549 Viromes outperform total metagenomes in revealing the spatiotemporal patterns of agricultural soil viral communities
Santos-Medellin, C.; Zinke, L. A.; ter Horst, A. M.; Gelardi, D. L.; Parikh, S. J.; Emerson, J. B.
10.1101/2020.08.06.237214 — microbiology — Posted on 2020-08-06
3550 Genomic and phenotypic diversity of Enterococcus faecalis isolated from endophthalmitis
Chilambi, G. S.; Nordstrom, H. R.; Evans, D. R.; Kowalski, R. P.; Dhaliwal, D. K.; Jhanji, V.; Shanks, R. M.; Van Tyne, D.
10.1101/2020.08.05.239061 — microbiology — Posted on 2020-08-06
3552 The DNA mimic protein BCAS0292 is involved in the regulation of virulence of Burkholderia cenocepacia
Dennehy, R.; Dignam, S.; McCormack, S.; Romano, M.; Hou, Y.; Ardill, L.; Whelan, M. V.; Drulis-Kawa, Z.; O Croinin, T.; Valvano, M. A.; Berisio, R.; McClean, S.
10.1101/2020.08.06.226779 — microbiology — Posted on 2020-08-06
3553 IL-4 receptor targeting as an effective immunotherapy against triple-negative breast cancer
Parveen, S.; Siddharth, S.; Cheung, L. S.; Kumar, A.; Murphy, J. R.; Sharma, D.; Bishai, W. R.
10.1101/2020.08.05.238824 — immunology — Posted on 2020-08-06
3561 Kinetics of Plasma cfDNA Predicts Clinical Response in Non-Small Cell Lung Cancer Patients
Zhou, X.; Li, C.; Zhang, Z.; Li, D.; Du, J.; Li, R.; Ho, E.; Zhang, A.; Okunieff, P.; Lu, J.; Sha, M.
10.1101/2020.08.05.238626 — cancer biology — Posted on 2020-08-06
3562 CBX2 and CBX7 antagonistically regulate metabolic reprogramming in breast cancer
Iqbal, M. A.; Siddiqui, S.; Ur Rehman, A.; Siddiqui, F. A.; Singh, P.; Kumar, B.; Saluja, D.
10.1101/2020.08.06.239129 — cancer biology — Posted on 2020-08-06
3565 matchms - processing and similarity evaluation of mass spectrometry data
Huber, F.; Verhoeven, S.; Meijer, C.; Spreeuw, H.; Villanueva Castilla, E. M.; Geng, C.; van der Hooft, J. J.; Rogers, S.; Belloum, A.; Diblen, F.; Spaaks, J. H.
10.1101/2020.08.06.239244 — bioinformatics — Posted on 2020-08-06
3573 Rodent mnemonic similarity task performance requires the prefrontal cortex
Johnson, S. A.; Zequeira, S.; Turner, S. M.; Maurer, A. P.; Bizon, J. L.; Burke, S. N.
10.1101/2020.08.05.238725 — neuroscience — Posted on 2020-08-06
3575 Development and characterization of infectious clones of two strains of Usutu virus
Bates, T. A.; Chuong, C.; Hawks, S. A.; Rai, P.; Salgado, R. M.; Duggal, N. K.; Weger-Lucarelli, J. A.
10.1101/2020.08.05.238543 — molecular biology — Posted on 2020-08-06
3576 Functional drug susceptibility testing based on biophysical measurements predicts patient outcome in glioblastoma patient-derived neurosphere models
Stockslager, M. A.; Malinowski, S.; Touat, M.; Yoon, J. C.; Geduldig, J.; Mirza, M.; Kim, A. S.; Wen, P. Y.; Chow, K.-H.; Ligon, K. L.; Manalis, S. R.
10.1101/2020.08.05.238154 — cancer biology — Posted on 2020-08-06
3578 Identification of pituitary thyrotrope signature genes and regulatory elements
Daly, A. Z.; Dudley, L. A.; Peel, M. T.; Liebhaber, S. A.; Parker, S. C.; Camper, S. A.
10.1101/2020.08.05.238253 — genomics — Posted on 2020-08-06
3584 Neuron-intrinsic NF-κB Signaling Mediates Reovirus Virulence
Dermody, T.; Pruijssers, A. J.; Taylor, G. M.; Brigleb, P.; Shang, P.; Urbanek, K.; Brwon, J.
10.1101/2020.08.05.238220 — microbiology — Posted on 2020-08-06
3585 Persistent bacterial coinfection of a COVID-19 patient caused by a genetically adapted Pseudomonas aeruginosa chronic colonizer
Qu, J.-X.; Cai, Z.; Liu, Y.; Duan, X.; Han, S.; Zhu, Y.; Jiang, Z.; Zhang, Y.; Zhuo, C.; Liu, Y.; Liu, Y.; Liu, L.; Yang, L.
10.1101/2020.08.05.238998 — microbiology — Posted on 2020-08-06
3586 IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection
Rosa, B. A.; Ahmed, M.; Singh, D. K.; Choreno-Parra, J. A.; Cole, J.; Jimenez-Alvarez, L. A.; Rodriguez-Reyna, T. S.; Singh, B.; Golzalez, O.; Carrion, R.; Schlesinger, L. S.; Martin, J.; Zuniga, J.; Mitreva, M.; Khader, S. A.; Kaushal, D.
10.1101/2020.08.06.239798 — immunology — Posted on 2020-08-06
3587 Biological warfare between Drosophila species hints for sustainable crop protection
rombaut, a.; Gallet, R.; Qitout, K.; Samy, M.; Guilhot, R.; Ghirardini, P.; Becher, P. G.; Xuereb, A.; Gibert, P.; Fellous, S.
10.1101/2020.08.05.238055 — ecology — Posted on 2020-08-06
3590 Signatures and mechanisms of efficacious therapeutic ribonucleotides against SARS-CoV-2 revealed by analysis of its replicase using magnetic tweezers
Seifert, M.; Bera, S. C.; van Nies, P.; Kirchdoerfer, R. N.; Shannon, A.; Le, T.-T.-N.; Grove, T. L.; Papini, F. S.; Arnold, J. J.; Almo, S. C.; Canard, B.; Depken, M.; Cameron, C. E.; Dulin, D.
10.1101/2020.08.06.240325 — biophysics — Posted on 2020-08-06
3594 DDR1-INDUCED NEUTROPHIL EXTRACELLULAR TRAPS DRIVE PANCREATIC CANCER METASTASIS
Deng, J.; Kang, Y.; Cheng, C.-C.; Li, X.; Dai, B.; Katz, M. H.; Men, T.; Kim, M. P.; Koay, E.; Huang, H.; Brekken, R. A.; Fleming, J. B.
10.1101/2020.08.05.238097 — cancer biology — Posted on 2020-08-06
3597 Peptide Antidotes to SARS-CoV-2 (COVID-19)
Watson, A.; Ferreira, L. M. R.; Hwang, P.; Xu, J.; Stroud, R.
10.1101/2020.08.06.238915 — bioengineering — Posted on 2020-08-06
3599 Dendrimer-targeted immunosuppression of microglia reactivity super-accelerates photoreceptor regeneration in the zebrafish retina
Emmerich, K. B.; White, D. T.; Kambhamptati, S. P.; Lee, G. Y.; Fu, T.-M.; Sahoo, A.; Betzig, E.; Kannan, R. M.; Mumm, J. S.; Saxena, M. T.
10.1101/2020.08.05.238352 — neuroscience — Posted on 2020-08-06
3601 Linked deterioration of early visual perception, function and structure in healthy human aging
Silva, M. F.; Harvey, B. M.; Jorge, L.; Canario, N.; Machado, F.; Soares, M.; Castelo-Branco, M.
10.1101/2020.08.05.238014 — neuroscience — Posted on 2020-08-06
3602 Structure of mycobacterial ATP synthase with the TB drug bedaquiline
Guo, H.; Courbon, G. M.; Bueler, S. A.; Mai, J.; Liu, J.; Rubinstein, J. L.
10.1101/2020.08.06.225375 — biochemistry — Posted on 2020-08-06
3603 High-throughput siRNA screening reveals functional interactions and redundancies of human processive exoribonucleases
Dziembowski, A.; Szczesny, R. J.; Hojka-Osinska, A.; Chlebowski, A.; Kłosowska-Kosicka, K.; Affek, K.; Owczarek, E. P.
10.1101/2020.08.05.238006 — systems biology — Posted on 2020-08-06
3607 Neurodegeneration and neuroinflammation are linked, but independent of alpha-synuclein inclusions, in a seeding/spreading mouse model of Parkinson disease
Garcia, P.; Juergens-Wemheuer, W.; Uriarte, O.; Schmit, K. J.; Masuch, A.; Brioschi, S.; Wiehofen, A.; Koncina, E.; Coowar, D.; Heurtaux, T.; Glaab, E.; Balling, R.; Sousa, C.; Michelucci, A.; Kaoma, T.; Nicot, N.; Pfander, T.; Schulz-Schaeffer, W.; Allouche, A.; Fischer, N.; Biber, K.; Mittelbronn, M.; Buttini, M.
10.1101/2020.08.05.237750 — neuroscience — Posted on 2020-08-06
3609 Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors
Osipiuk, J.; Azizi, S.-A.; Dvorkin, S.; Endres, M.; Jedrzejczak, R.; Jones, K. A.; Kathayat, R. S.; Lisnyak, V. G.; Maki, S. L.; Kang, S.; Kim, Y.; Nicolaescu, V.; Taylor, C. A.; Tesar, C.; Zhang, Y.-A.; Zhou, Z.; Randall, G.; Michalska, K.; Snyder, S. A.; Dickinson, B. C.; Joachimiak, A.
10.1101/2020.08.06.240192 — molecular biology — Posted on 2020-08-06
3610 Hypertonic saline solution inhibits SARS-CoV-2 in vitro assay
Machado, R. R. G.; Glaser, T.; Araujo, D. B.; Petiz, L. L.; Oliveira, D. B. L.; Durigon, G. S.; Leal, A. L.; Pinho, J. R. R.; Ferreira, L. C. S.; Ulrich, H.; Durigon, E. L. R.; Guzzo, C. R.
10.1101/2020.08.04.235549 — microbiology — Posted on 2020-08-06
3611 Capturing and Recreating Diverse Antibody Repertoires as Multivalent Recombinant Polyclonal Antibody Drugs
Keating, S. M.; Mizrahi, R. A.; Adams, M. S.; Asensio, M. A.; Benzie, E.; Carter, K. P.; Chiang, Y.; Edgar, R. C.; Gautam, B. K.; Gras, A.; Leong, J.; Leong, R.; Lim, Y. W.; Manickam, V. A.; Medina-Cucurella, A. V.; Niedecken, A. R.; Saini, J.; Simons, J. F.; Spindler, M. J.; Stadtmiller, K.; Tinsley, B.; Wagner, E. K.; Wayham, N.; Tracy, L.; Vingsbo Lundberg, C. C.; Buscher, D.; Terencio, J. V.; Roalfe, L.; Pearce, E.; Richardson, H.; Goldblatt, D.; Ramjag, A. T.; Carrington, C. V. F.; Simmons, G.; Muench, M.; Chamow, S.; Monroe, B.; Olson, C.; Oguin, T. H.; Lynch, H.; Jeanfreau, R.; Meyer, E
10.1101/2020.08.05.232975 — immunology — Posted on 2020-08-06
3612 Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate
Bangaru, S.; Ozorowski, G.; Turner, H. L.; Antanasijevic, A.; Huang, D.; Wang, X.; Torres, J. L.; Diedrich, J. K.; Tian, J.-H.; Portnoff, A. D.; Patel, N.; Massare, M. J.; Yates, J. R.; Nemazee, D.; Paulson, J. C.; Glenn, G.; Smith, G.; Ward, A. B.
10.1101/2020.08.06.234674 — immunology — Posted on 2020-08-06
3613 Phylogenetic analysis of SARS-CoV-2 data is difficult
Morel, B.; Barbera, P.; Czech, L.; Bettisworth, B.; Huebner, L.; Lutteropp, S.; Serdari, D.; Kostaki, E.-G.; Mamais, I.; Kozlov, A.; Pavlidis, P. M.; Paraskevis, D.; Stamatakis, A.
10.1101/2020.08.05.239046 — evolutionary biology — Posted on 2020-08-06
3617 New strains for tissue-specific RNAi studies in Caenorhabditis elegans
Watts, J. L.; Watts, J. S.; Harrison, H. F.; Omi, S.; Dalelio, J.; Guenther, Q.; PUJOL, N.
10.1101/283325 — molecular biology — Posted on 2020-08-06
3620 Automatic inference of demographic parameters using Generative Adversarial Networks
Wang, Z.; Wang, J.; Kourakos, M.; Hoang, N.; Lee, H. H.; Mathieson, I.; Mathieson, S.
10.1101/2020.08.05.237834 — genomics — Posted on 2020-08-06
3621 Dissecting mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage
Zou, X.; Koh, G. C. C.; Nanda, A. S.; Degasperi, A.; Urgo, K.; Roumeliotis, T.; Agu, C. A.; Side, L.; Brice, G.; Perez-Alonso, V.; Rueda, D.; Badja, C.; Young, J.; Gomez, C.; Bushell, W.; Harris, R.; Choudhary, J.; Jiricny, J. I.; Skarnes, W. C.; Nik-Zainal, S.
10.1101/2020.08.04.234245 — genomics — Posted on 2020-08-06
3622 Incorporation of DNA methylation into eQTL mapping in African Americans.
Singh, A.; Zhong, Y.; Park, C. S.; Nahlawi, L.; Alarcon, C.; De, T.; Perera, M.
10.1101/2020.08.05.238030 — genomics — Posted on 2020-08-06
3625 Dynamic NHE1-Calmodulin complexes of varying stoichiometry and structure regulate Ca2+-dependent NHE1 activation
Sjogaard-Frich, L. M.; Prestel, A.; Pedersen, E. S.; Severin, M.; Olsen, J. G.; Kragelund, B. B.; Pedersen, S. F.
10.1101/2020.08.04.236463 — cell biology — Posted on 2020-08-06
3626 Liver x receptor alpha drives chemoresistance in response to side-chain hydroxycholesterols in triple negative breast cancer
Hutchinson, S. A.; Websdale, A.; Lianto, P.; Cioccoloni, G.; Roberg-Larsen, H.; Kim, B.; Rose, A.; Soteriou, C.; Wastall, L. M.; Williams, B.; Henn, M.; Chen, J. J.; Ma, L.; Moore, J. B.; Nelson, E. R.; Hughes, T. A.; Thorne, J. L.
10.1101/2020.08.04.235697 — cancer biology — Posted on 2020-08-06
3628 A Legionella effector ADP-ribosyltransferase inactivates glutamate dehydrogenase
Black, M. H.; Osinski, A.; Gradowski, M.; Servage, K. A.; Pawłowski, K.; Tagliabracci, V. S.
10.1101/2020.08.03.234963 — biochemistry — Posted on 2020-08-06
3629 Oak regeneration at the arid boundary of the temperate deciduous forest biome: insights from a seeding and watering experiment
Erdos, L.; Szitar, K.; Ollerer, K.; Onodi, G.; Kertesz, M.; Torok, P.; Barath, K.; Tolgyesi, C.; Batori, Z.; Somay, L.; Orban, I.; Kroel-Dulay, G.
10.1101/2020.08.05.237719 — ecology — Posted on 2020-08-06
3631 Marcksl1 modulates endothelial cell mechanoresponse to haemodynamic forces to control blood vessel shape and size
Kondrychyn, I.; Kelly, D. J.; Taberner, N.; Nomori, A.; Kato, K.; Chong, J.; Nakajima, H.; Okuda, S.; Mochizuki, N.; Phng, L.-K.
10.1101/2020.08.06.237305 — cell biology — Posted on 2020-08-06
3634 3D imaging and morphometry of the heart capillary system in spontaneously hypertensive rats and normotensive controls
Olianti, C.; Costantini, I.; Giardini, F.; Lazzeri, E.; Crocini, C.; Ferrantini, C.; Pavone, F.; Camici, P. G.; Sacconi, L.
10.1101/2020.08.05.237487 — physiology — Posted on 2020-08-06
3637 Dynamic brain-to-brain concordance and behavioral mirroring as a mechanism of the patient-clinician interaction
Ellingsen, D.-M.; Isenburg, K.; Jung, C.; Lee, J.; Gerber, J.; Mawla, I.; Sclocco, R.; Jensen, K. B.; Edwards, R. R.; Kelley, J. M.; Kirsch, I.; Kaptchuk, T. J.; Napadow, V.
10.1101/2020.08.05.237511 — neuroscience — Posted on 2020-08-06
3639 A comprehensive macaque fMRI pipeline and hierarchical atlas
Jung, B.; Taylor, P. A.; Seidlitz, J.; Sponheim, C.; Perkins, P.; Ungerleider, L. G.; Glen, D.; Messinger, A.
10.1101/2020.08.05.237818 — neuroscience — Posted on 2020-08-06
3640 Cortical silencing results in paradoxical fMRI overconnectivity
Canella, C.; Rocchi, F.; Noei, S.; Gutierrez-Barragan, D.; Coletta, L.; Galbusera, A.; Vassanelli, S.; Pasqualetti, M.; Iurilli, G.; Panzeri, S.; Gozzi, A.
10.1101/2020.08.05.237958 — neuroscience — Posted on 2020-08-06
3642 Tracking H3K27me3 and H4K20me1 dynamics during XCI reveals similarities in recruitment mechanism
Tjalsma, S. J. D.; Hori, M.; Sato, Y.; Bousard, A.; Ohi, A.; Raposo, A. C.; Roensch, J.; Le Saux, A.; Nogami, J.; Maehara, K.; Kujirai, T.; Ohkawa, Y.; Kurumizaka, H.; da Rocha, S. T.; Zylicz, J. J.; Kimura, H.; Heard, E.
10.1101/2020.08.06.228346 — developmental biology — Posted on 2020-08-06
3644 vCOMBAT: a Novel Tool to Create and Visualize a COmputational Model of Bacterial Antibiotic Target-binding
Tran, V. N.-N.; Shams, A.; Ascioglu, S.; Martinecz, A.; Liang, J.; Clarelli, F.; Mostowy, R.; Cohen, T.; Abel zur Wiesch, P.
10.1101/2020.08.05.236711 — bioinformatics — Posted on 2020-08-06
3646 Gene expression evolution in pattern-triggered immunity within Arabidopsis thaliana and across Brassicaceae species
Winkelmüller, T. M.; Entila, F.; Anver, S.; Piasecka, A.; Song, B.; Dahms, E.; Sakakibara, H.; Gan, X.; Kułak, K.; Sawikowska, A.; Krajewski, P.; Tsiantis, M.; Garrido-Oter, R.; Fukushima, K.; Schulze-Lefert, P.; Laurent, S.; Bednarek, P.; Tsuda, K.
10.1101/2020.07.29.227397 — plant biology — Posted on 2020-08-05
3647 Ultrasound Monitoring of Descending Aortic Aneurysms and Dissections in Mice
Sawada, H.; Franklin, M. K.; Moorleghen, J. J.; Howatt, D. A.; Kukida, M.; Lu, H. S.; Daugherty, A.
10.1101/2020.04.18.048298 — pathology — Posted on 2020-08-05
3649 Gene regulatory networks controlling differentiation, survival, and diversification of hypothalamic Lhx6-expressing GABAergic neurons.
Kim, D. W.; Liu, K.; Wang, Z. Q.; Zhang, Y. S.; Bathini, A.; Brown, M. P.; Lin, S. H.; Washington, P. W.; Sun, C.; Lindtner, S.; Lee, B.; Wang, H.; Shimogori, T.; Rubenstein, J. L. R.; Blackshaw, S.
10.1101/2020.05.21.106963 — neuroscience — Posted on 2020-08-05
3651 The RNA phosphatase PIR-1 regulates endogenous small RNA pathways in C. elegans
Chaves, D. A.; Hui, D.; Li, L.; Moresco, J. J.; Oh, M. E.; Conte, D.; Yates, J. R.; Mello, C. C.; Gu, W.
10.1101/2020.08.03.235143 — molecular biology — Posted on 2020-08-05
3652 Antigen-specific induction of CD4+CD8αα+ intraepithelial T lymphocytes byBacteroidetes species
Bousbaine, D.; Bhagchandani, P.; London, M.; Mimee, M.; Olesen, S.; Poyet, M.; Cheloha, R. W.; Sidney, J.; Ling, J.; Gupta, A.; Lu, T. K.; Sette, A.; Alm, E. J.; Mucida, D.; Bilate, A. M.; Ploegh, H. L.
10.1101/2020.08.05.236513 — immunology — Posted on 2020-08-05
3654 Incorporation of DNA methylation into eQTL mapping in African Americans.
Singh, A.; Zhong, Y.; Park, C. S.; Nahlawi, L.; Alarcon, C.; De, T.; Perera, M.
10.1101/2020.08.05.238030 — genomics — Posted on 2020-08-05
3655 Age-related DNA methylation changes are sex-specific: a comprehensive assessment
Yusipov, I.; Bacalini, M. G.; Kalyakulina, A.; Krivonosov, M.; Pirazzini, C.; Gensous, N.; Ravaioli, F.; Milazzo, M.; Vedunova, M.; Fiorito, G.; Gagliardi, A.; Polidoro, S.; Garagnani, P.; Ivanchenko, M.; Franceschi, C.
10.1101/2020.01.15.905224 — genomics — Posted on 2020-08-05
3656 locStra: Fast analysis of regional/global stratification in whole genome sequencing (WGS) studies
Hahn, G.; Lutz, S. M.; Hecker, J.; Prokopenko, D.; Cho, M.; Silverman, E. K.; Weiss, S.; Lange, C.
10.1101/2020.03.06.981050 — genetics — Posted on 2020-08-06
3659 CODEX, a neural network approach to explore signaling dynamics landscapes
Jacques, M.-A.; Dobrzynski, M.; Gagliardi, P. A.; Sznitman, R.; Pertz, O.
10.1101/2020.08.05.237842 — cell biology — Posted on 2020-08-06
3661 Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival
Agelidis, A.; Turturice, B. A.; Suryawanshi, R. K.; Yadavalli, T.; Jaishankar, D.; Ames, J.; Hopkins, J.; Koujah, L.; Patil, C. D.; Hadigal, S. R.; Kyzar, E. J.; Campeau, A.; Wozniak, J. M.; Gonzalez, D. J.; Vlodavsky, I.; Li, J.-p.; Perkins, D. L.; Finn, P. W.; Shukla, D.
10.1101/2020.08.05.238758 — cell biology — Posted on 2020-08-06
3662 Age-independent influence of hematopoietic stem and progenitor cell populations during hematopoietic reconstitution
Gotzhein, F.; Aranyossy, T.; Thielecke, L.; Sonntag, T.; Thaden, V.; Fehse, B.; Mueller, I.; Glauche, I.; Cornils, K.
10.1101/2020.08.05.237891 — cell biology — Posted on 2020-08-06
3664 Clump sequencing exposes the spatial expression programs of intestinal secretory cells
Manco, R.; Averbukh, I.; Porat, Z.; Bahar Halpern, K.; Amit, I.; Itzkovitz, S.
10.1101/2020.08.05.237917 — cell biology — Posted on 2020-08-06
3667 Molecular details of protein condensates probed by microsecond-long atomistic simulations
Zheng, W.; Dignon, G. L.; Xu, X.; Regy, R. M.; Fawzi, N. L.; Kim, Y. C.; Best, R.; Mittal, J.
10.1101/2020.08.05.237008 — biophysics — Posted on 2020-08-06
3668 PI3K inhibition reverses migratory direction of single cells but not cell groups in electric field
Sun, Y.; Yue, H.; Copos, C.; Zhu, K.; Zhang, Y.; Gao, X.; Sun, Y.; Reid, B.; Lin, F.; Zhao, M.; Mogilner, A.
10.1101/2020.08.05.238170 — biophysics — Posted on 2020-08-06
3669 Liquid-liquid phase separation of tau driven by hydrophobic interaction facilitates fibrillization of tau
Lin, Y.; Fichou, Y.; Longhini, A. P.; Llanes, L. C.; Yin, Y.; Bazan, G. C.; Kosik, K. S.; Han, S.
10.1101/2020.08.05.237966 — biophysics — Posted on 2020-08-06
3670 Controllable Fusion of Human Brain Organoids Using Acoustofluidics
Ao, Z.; Cai, H.; Wu, Z.; Johnathon, J.; Wang, H.; Mackie, K.; Guo, F.
10.1101/2020.08.05.238113 — bioengineering — Posted on 2020-08-06
3671 Measurement of non-purified GPCR thermostability using the homogenous ThermoBRET assay
Hoare, B. L.; Kaur, A.; Dijon, N. C.; Holliday, N. D.; Sykes, D. A.; Veprintsev, D.
10.1101/2020.08.05.237982 — biochemistry — Posted on 2020-08-06
3674 Immune profiling of gliomas reveals a connection with Tau function and the tumor vasculature.
Sanchez-Gomez, P.; Sepulveda-Sanchez, J. M.; Cejalvo, T.; Hernandez-Lain, A.; Gargini, R.; Segura-Collar, B.; Mata-Martinez, P.; Herranz, B.; Cantero, D.; Ruano, Y.; Garcia-Perez, D.; Perez-Nunez, A.; Ramos, A.; Martin-Soberon, M. C.
10.1101/2020.07.17.208165 — cancer biology — Posted on 2020-08-05
3675 ATP dependent DNA transport within cohesin: Scc2 clamps DNA on top of engaged heads while Scc3 promotes entrapment within the SMC-kleisin ring
Collier, J. E.; Lee, B.-G.; Brunet-Roig, M.; Yatskevich, S.; Petela, N. J.; Metson, J.; Voulgaris, M.; Gonzalez Llamazares, A.; Lowe, J.; Nasmyth, K. A.
10.1101/2020.06.03.132233 — biochemistry — Posted on 2020-08-05
3676 Cheetah: a computational toolkit for cybergenetic control
Pedone, E.; de Cesare, I.; Zamora, C.; Haener, D.; Postiglione, L.; Shannon, B.; Savery, N.; Grierson, C. S.; di Barnardo, M.; Gorochowski, T. E.; Marucci, L.
10.1101/2020.06.25.171751 — synthetic biology — Posted on 2020-08-05
3678 Gut microbiome composition predicts summer core range size in a generalist and specialist ungulate
Wolf, J. F.; Kriss, K. D.; MacAulay, K. M.; Munro, K.; Patterson, B. R.; Shafer, A. B. A.
10.1101/2020.08.04.236638 — molecular biology — Posted on 2020-08-05
3680 Spontaneous replication fork collapse regulates telomere length homeostasis in wild type cells
Paschini, M.; Reyes, C. M.; Gillespie, A. E.; Lewis, K. A.; Glustrom, L. W.; Sharpee, T. O.; Wuttke, D. S.; Lundblad, V.
10.1101/2020.08.05.237172 — genetics — Posted on 2020-08-05
3684 The Structural Basis for SARM1 Inhibition, and Activation Under Energetic Stress
Sporny, M.; Guez-Haddad, J.; Khazma, T.; Yaron, A.; Dessau, M.; Mim, C.; Isupov, M. N.; Zalk, R.; Hons, M.; Opatowsky, Y.
10.1101/2020.08.05.238287 — biochemistry — Posted on 2020-08-05
3687 GroEL/ES Buffers Entropic Traps In Folding Pathway During Evolution Of A Model Substrate
Sadat, A.; Tiwari, S.; Verma, K.; Ray, A.; Ali, M.; Upadhyay, V.; Singh, A.; Chaphalkar, A.; Ghosh, A.; Chakraborty, R.; Chakraborty, K.; Mapa, K.
10.1101/2020.05.12.090233 — molecular biology — Posted on 2020-08-05
3689 Impact of trimethoprim on the river microbiome and antimicrobial resistance.
Delaney, J.; Raguideau, S.; Holden, J.; Zhang, L.; Tipper, H.; Hill, G.; Klumper, U.; Zhang, T.; James, R. S.; Travis, E. R.; Bowes, M. J.; Hawkey, P. M.; Lindstrom, H. S.; Tang, C.; Gaze, W. H.; Mead, A.; Quince, C. R.; Singer, A. C.; Wellington, E. M.
10.1101/2020.06.05.133348 — microbiology — Posted on 2020-08-05
3693 In silico Characterization of Class II Plant Defensins from Arabidopsis thaliana
Costa, L. M.; Pires, A. S.; Damaceno, N. B.; Rigueiras, P. O.; Maximiano, M. R.; Franco, O. L.; Porto, W. F.
10.1101/2020.04.27.065185 — bioinformatics — Posted on 2020-08-05
3700 Genomic and chemical diversity of Bacillus subtilis secondary metabolites against plant pathogenic fungi
Kiesewalter, H. T.; Lozano Andrade, C. N.; Wibowo, M.; Lenz Strube, M.; Maroti, G.; Snyder, D.; Jorgensen, T. S.; Larsen, T. O.; Cooper, V. S.; Weber, T.; Kovacs, A. T.
10.1101/2020.08.05.238063 — microbiology — Posted on 2020-08-05
3702 Offshore transport of floodwaters following extreme storms impacts sponge health and associated microbial communities
Shore, A.; Sims, J. A.; Grimes, M.; Howe-Kerr, L. I.; Stadler, L.; Sylvan, J. B.; Shamberger, K. E.; Davies, S. W.; Santiago-Vasquez, L. Z.; Correa, A. M.
10.1101/2020.04.27.064568 — microbiology — Posted on 2020-08-05
3703 Recapitulation of HIV-1 Env-Antibody Coevolution in Macaques Leading to Neutralization Breadth
Roark, R. S.; Li, H.; Williams, W. B.; Chug, H.; Mason, R. D.; Gorman, J.; Wang, S.; Lee, F.-H.; Rando, J.; Bonsignori, M.; Hwang, K.-K.; Saunders, K. O.; Wiehe, K.; Moody, M. A.; Hraber, P. T.; Wagh, K.; Giorgi, E. E.; Russell, R. M.; Bibollet-Ruche, F.; Liu, W.; Connell, J.; Smith, A. G.; DeVoto, J.; Murphy, A. I.; Smith, J.; Ding, W.; Zhao, C.; Chohan, N.; Okumura, M.; Rosario, C.; Ding, Y.; Lindemuth, E.; Bauer, A. M.; Bar, K. J.; Ambrozak, D.; Chao, C. W.; Chuang, G.-Y.; Geng, H.; Lin, B. C.; Louder, M. K.; Nguyen, R.; Zhang, B.; Lewis, M. G.; Raymond, D.; Doria-Rose, N. A.; Schramm, C. A
10.1101/2020.08.05.237693 — immunology — Posted on 2020-08-05
3705 N-terminal Domain Regulates Steroid Activation of Elephant Shark Glucocorticoid and Mineralocorticoid Receptors
Katsu, Y.; Shariful, I. M.; Lin, X.; Takagi, W.; Urushitani, H.; Kohno, S.; Hyodo, S.; Baker, M. E.
10.1101/822718 — evolutionary biology — Posted on 2020-08-05
3708 The CRISPR-Cas9 crATIC HeLa transcriptome: Characterization of a novel cellular model for ATIC deficiency and ZMP accumulation
Mazzarino, R. C.; Baresova, V.; Zikanova, M.; Duval, N.; Wilkinson, T. G.; Patterson, D.; Vacano, G. N.
10.1101/2020.04.28.067066 — cell biology — Posted on 2020-08-05
3712 Dynamics of the COVID -19 Related Publications
Sarkar, B.; Munshi, A.; Ghosh, B.; Ganesh, T.; Manikandan, A.; Biswal, S. S.; Sahid, T.; B, R.; Sengupta, S.; Roychaowdhary, S.; Bhattacharya, J.; Gazi, M.; De, A.; George, K.; Ghosh, T.; Akhter, J.; Mandal, S.; Gupta, R.; Roy, S.; Jassal, K.; Rastogi, K.; Bansal, K.; Chaterjee, P.; Biswas, L. N.; Bondopadhay, S.; Pradhan, A.; Mohanti, B. K.
10.1101/2020.08.05.237313 — scientific communication and education — Posted on 2020-08-05
3713 Epitomic analysis of the specificity of conformation-dependent, anti-aβ amyloid monoclonal antibodies
Reyes-Ruiz, J. M.; Nakajima, R.; Baghallab, I.; Goldschmidt, L.; Kumosani, T.; Felgner, P. L.; Glabe, C. G.
10.1101/2020.08.05.238105 — neuroscience — Posted on 2020-08-05
3714 Pre-attentive processing of neutral and emotional sounds in congenital amusia
Pralus, A.; Gomot, M.; Graves, J.; Cholvy, F.; Fornoni, L.; Tillmann, B.; Caclin, A.
10.1101/2020.08.05.238204 — neuroscience — Posted on 2020-08-05
3715 Individualized characterization of volumetric development in the preterm brain
Dimitrova, R.; Arulkumaran, S.; Carney, O.; Chew, A.; Falconer, S.; Ciarrusta, J.; Wolfers, T.; Batalle, D.; Cordero-Grande, L.; Price, A. N.; Teixeira, R. P.; Hughes, E.; Egloff, A.; Hutter, J.; Makropoulos, A.; Robinson, E. C.; Schuh, A.; Vecchiato, K.; Steinweg, J. K.; Macleod, R.; Marquand, A. F.; McAlonan, G.; Rutherford, M. A.; Counsell, S. J.; Smith, S. M.; Rueckert, D.; Hajnal, J. V.; O'Muircheartaigh, J.; Edwards, A. D.
10.1101/2020.08.05.228700 — neuroscience — Posted on 2020-08-05
3716 Astrocytes dystrophy in ageing brain parallels impaired synaptic plasticity
Popov, A.; Brazhe, A.; Denisov, P.; Sutyagina, O.; Lazareva, N.; Verkhratsky, A.; Semyanov, A.
10.1101/2020.08.05.237420 — neuroscience — Posted on 2020-08-05
3718 Post-Transcriptional Regulation of Antiviral Gene Expression by N6-Methyladenosine
McFadden, M. J.; McIntyre, A. B. R.; Mourelatos, H.; Abell, N. S.; Gokhale, N. S.; Ipas, H.; Xhemalce, B.; Mason, C. E.; Horner, S. M.
10.1101/2020.08.05.238337 — immunology — Posted on 2020-08-05
3719 PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaques
Kauffman, K. D.; Sakai, S.; Lora, N. E.; Namasivayam, S.; Baker, P. J.; Kamenyeva, O.; Foreman, T. W.; Nelson, C. E.; Oliveira-de-Souza, D.; Vinhaes, C. L.; Yaniv, Z.; Lindestam Arleham, C. S.; Sette, A.; Freeman, G. J.; Moore, R.; the NIAID/DIR Tuberculosis Imaging Program, ; Sher, A.; Mayer-Barber, K. D.; Andrade, B. B.; Kabat, J.; Via, L. E.; Barber, D. L.
10.1101/2020.08.05.237883 — immunology — Posted on 2020-08-05
3721 Spontaneous replication fork collapse regulates telomere length homeostasis in wild type cells
Paschini, M.; Reyes, C. M.; Gillespie, A. E.; Lewis, K. A.; Glustrom, L. W.; Sharpee, T. O.; Wuttke, D. S.; Lundblad, V.
10.1101/2020.08.05.237172 — genetics — Posted on 2020-08-05
3722 Orphan CpG islands boost the regulatory activity of poisedenhancers and dictate the responsiveness of their target genes
Pachano, T.; Sanchez-Gaya, V.; Mariner-Fauli, M.; Ealo, T.; Asenjo, H. G.; Respuela, P.; Cruz-Molina, S.; van IJcken, W.; Landeira, D.; Rada-Iglesias, A.
10.1101/2020.08.05.237768 — genetics — Posted on 2020-08-05
3725 CRISPR/Cas9 technology abolishes the BCR/ABL1 oncogene effect in chronic myeloid leukemia and restores normal hematopoiesis
Vuelta, E.; Ordonez, J. L.; Alonso-Perez, V.; Mendez, L.; Hernandez-Carabias, P.; Saldana, R.; Sevilla, J.; Sebastian, E.; Muntion, S.; Sanchez-Guijo, F.; Hernandez-Rivas, J. M.; Garcia-Tunon, I.; Sanchez-Martin, M. A.
10.1101/2020.08.05.237610 — cancer biology — Posted on 2020-08-05
3732 H3 K27M and EZHIP impede H3K27-methylation spreading by inhibiting allosterically stimulated PRC2
Jain, S. U.; Rashoff, A. Q.; Krabbenhoft, S. D.; Hoelper, D.; Do, T. J.; Gibson, T. J.; Lundgren, S. M.; Bondra, E. R.; Deshmukh, S.; Harutyunyan, A. S.; Juretic, N.; Jabado, N.; Harrison, M.; Lewis, P. W.
10.1101/2020.08.05.236737 — cancer biology — Posted on 2020-08-05
3733 The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines
Luban, J.; Sattler, R.; Muhlberger, E.; Graci, J. D.; Cao, L.; Weetall, M.; Trotta, C.; Colacino, J. M.; Bavari, S.; Strambio-De-Castillia, C.; Suder, E. L.; Wang, Y.; Soloveva, V.; Cintron-Lue, K.; Naryshkin, N. A.; Pykett, M.; Welch, E. M.; O'Keefe, K.; Kong, R.; Goodwin, E.; Jacobson, A.; Paessler, S.; Peltz, S.
10.1101/2020.08.05.238394 — immunology — Posted on 2020-08-05
3734 Analysis of the potential impact of genomic variants in SARS-CoV-2 genomes from India on molecular diagnostic assays
Jain, A.; Rophina, M.; Mahajan, S.; Krishnan, B. B.; Sharma, M.; Mandal, S.; Fernandez, T.; Sultanji, S.; Mathew, S.; Sivasubbu, S.; Scaria, V.
10.1101/2020.08.05.238618 — genomics — Posted on 2020-08-05
3736 Alveolitis in severe SARS-CoV-2 pneumonia is driven by self-sustaining circuits between infected alveolar macrophages and T cells
Grant, R. A.; Morales-Nebreda, L.; Markov, N. S.; Swaminathan, S.; Guzman, E. R.; Abbott, D. A.; Donnelly, H. K.; Donayre, A.; Goldberg, I. A.; Klug, Z. M.; Borkowski, N.; Lu, Z.; Kihshen, H.; Politanska, Y.; Sichizya, L.; Kang, M.; Shilatifard, A.; Qi, C.; Argento, A. C.; Kruser, J. M.; Malsin, E. S.; Pickens, C. O.; Smith, S.; Walter, J. M.; Pawlowski, A. E.; Schneider, D.; Nannapaneni, P.; Abdala-Valencia, H.; Bharat, A.; Gottardi, C. J.; Budinger, G. S.; Misharin, A. A.; Singer, B. D.; Wunderink, R. G.; The NU SCRIPT Study Investigators,
10.1101/2020.08.05.238188 — immunology — Posted on 2020-08-05
3738 Structure-Based Design of a Cyclic Peptide Inhibitor of the SARS-CoV-2 Main Protease
Kreutzer, A. G.; Krumberger, M.; Parrocha, C. M. T.; Morris, M. A.; Guaglianone, G.; Nowick, J. S.
10.1101/2020.08.03.234872 — biochemistry — Posted on 2020-08-05
3739 The coding capacity of SARS-CoV-2
Finkel, Y.; Mizrahi, O.; Nachshon, A.; Weingarten-Gabbay, S.; Morgenstern, D.; Yahalom-Ronen, Y.; Tamir, H.; Achdout, H.; Stein, D.; Israeli, O.; Beth-Din, A.; Melamed, S.; Weiss, S.; Isrealy, T.; Paran, N.; Schwartz, M.; Stern-Ginossar, N.
10.1101/2020.05.07.082909 — microbiology — Posted on 2020-08-05
3741 IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 and other diseases with tissue inflammation
Zhang, F.; Mears, J. R.; Shakib, L.; Beynor, J. I.; Shanaj, S.; Korsunsky, I.; Nathan, A.; Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus, ; Donlin, L. T.; Raychaudhuri, S.
10.1101/2020.08.05.238360 — genomics — Posted on 2020-08-05
3743 Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis
Ferrarini, M. G.; Lal, A.; Rebollo, R.; Gruber, A.; Guarracino, A.; Martinez Gonzalez, I.; Floyd, T.; Siqueira de Oliveira, D.; Shanklin, J.; Beausoleil, E.; Pusa, T.; Pickett, B.; Aguiar-Pulido, V.
10.1101/2020.07.28.225581 — bioinformatics — Posted on 2020-08-05
3744 An improved Nicotiana benthamiana strain for aphid and whitefly research
Feng, H.; Acosta-Gamboa, L.; Kruse, L. H.; Nava Fereira, A. R.; Shakir, S.; Xu, H.; Sunter, G.; Gore, M. A.; Moghe, G. D.; Jander, G.
10.1101/2020.08.04.237180 — plant biology — Posted on 2020-08-05
3745 Interleukin-22 mediated renal metabolic reprogramming via PFKFB3 to treat kidney injury
Chen, W.; Shen, Y.; Fan, J.; Zeng, X.; Zhang, X.; Zhang, J.; Luan, J.; Fang, S.; Mei, X.; Ju, D.
10.1101/2020.08.04.237347 — pharmacology and toxicology — Posted on 2020-08-05
3746 Evolving trait correlations underlie multi-trait adaptation in a eukaryotic alga
Walworth, N. G.; Hinners, J.; Argyle, P.; Doblin, M. A.; Collins, S.; Levine, N. M.
10.1101/2020.08.04.237230 — microbiology — Posted on 2020-08-05
3748 Evolutionary dynamics of SARS-CoV-2 nucleocapsid protein (N protein) and its consequences
Rahman, M. S.; Islam, M. R.; Ul Alam, A. S. M. R.; Islam, I.; Hoque, M. N.; Akter, S.; Rahaman, M. M.; Sultana, M.; Hossain, M. A.
10.1101/2020.08.05.237339 — evolutionary biology — Posted on 2020-08-05
3749 Statin-boosted cellular uptake of penetratin due to reduced membrane dipole potential
Batta, G.; Karpati, L.; Fulaneto, G.; Tarapcsak, S.; Kovacs, T.; Zakany, F.; Mandity, I. M.; Nagy, P.
10.1101/2020.08.04.236984 — cell biology — Posted on 2020-08-05
3751 Different activation signatures in the primary sensorimotor and higher-level regions for haptic three-dimensional curved surface exploration
Yang, J.; Molfese, P. J.; Yu, Y.; Handwerker, D. A.; Chen, G.; Taylor, P. A.; Ejima, Y.; Wu, J.; Bandettini, P. A.
10.1101/2020.08.04.235275 — neuroscience — Posted on 2020-08-05
3753 Rapid GMP-compliant expansion of SARS-CoV-2-specific T cells from convalescent donors for use as an allogeneic cell therapy for COVID-19
Cooper, R. S.; Fraser, A. R.; Smith, L.; Burgoyne, P.; Imlach, S. N.; Jarvis, L. M.; Zahara, S.; Turner, M. L.; Campbell, J. D.
10.1101/2020.08.05.237867 — immunology — Posted on 2020-08-05
3754 FeS-cluster coordination of vertebrate thioredoxins regulates suppression of hypoxia-induced factor 2α through iron regulatory protein 1
Berndt, C.; Hanschmann, E.-M.; Urbainsky, C.; Jordt, L. M.; Mueller, C. S.; Bodnar, Y.; Schippers, S.; Handorf, O.; Nowack, R.; Moulis, J.-M.; Schulzke, C.; Schuenemann, V.; Lillig, C. H.
10.1101/2020.08.04.235721 — biochemistry — Posted on 2020-08-05
3755 Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity
Hoffmann, M.; Hofmann-Winkler, H.; Smith, J. C.; Krueger, N.; Sorensen, L. K.; Sogaard, O. S.; Hasselstrom, J. B.; Winkler, M.; Hempel, T.; Raich, L.; Olsson, S.; Yamazoe, T.; Yamatsuta, K.; Mizuno, H.; Ludwig, S.; Noe, F.; Sheltzer, J. M.; Kjolby, M.; Poehlmann, S.
10.1101/2020.08.05.237651 — molecular biology — Posted on 2020-08-05
3756 Host metabolic reprogramming in response to SARS-Cov-2 infection
Moolamalla, S. T. R.; Chauhan, R.; Priyakumar, U. D.; Vinod, P. K.
10.1101/2020.08.02.232645 — bioinformatics — Posted on 2020-08-05
3760 Immune gene expression covaries with gut microbiome composition in stickleback
Fuess, L. E.; Den Haan, S.; Ling, F.; Weber, J. N.; Steinel, N. C.; Bolnick, D. I.
10.1101/2020.08.04.236786 — immunology — Posted on 2020-08-05
3761 Low Quantity single strand CAGE (LQ-ssCAGE) maps regulatory enhancers and promoters
Takahashi, H.; Nishiyori-Sueki, H.; Ramilowski, J. A.; Itoh, M.; Carninci, P.
10.1101/2020.08.04.231969 — genomics — Posted on 2020-08-05
3762 Concerted evolution reveals co-adapted amino acid substitutions in frogs that prey on toxic toads
Mohammadi, S.; Yang, L.; Harpak, A.; Herrera-Alvarez, S.; Rodriguez-Ordonez, M. d. P.; Peng, J.; Zhang, K.; Storz, J. F.; Dobler, S.; Crawford, A. J.; Andolfatto, P.
10.1101/2020.08.04.234435 — evolutionary biology — Posted on 2020-08-05
3763 Phenological displacement is uncommon among sympatric angiosperms
Park, D. S.; Breckheimer, I. K.; Ellison, A. M.; Lyra, G. M.; Davis, C. C.
10.1101/2020.08.04.236935 — ecology — Posted on 2020-08-05
3765 Super-human cell death detection with biomarker-optimized neural networks
Linsley, J. W.; Linsley, D.; Lamstein, J.; Ryan, G.; Shah, K.; Castello, N. A.; Oza, V.; Kalra, J.; Wang, S.; Tokuno, Z.; Javaherian, A.; Serre, T.; Finkbeiner, S.
10.1101/2020.08.04.237032 — cell biology — Posted on 2020-08-05
3774 Effect of sub-lethal prenatal endotoxemia on murine placental transport systems and lipid homeostasis
Reginatto, M. W.; Fontes, K. N.; Monteiro, V. S.; Liacone, N.; Andrade, C. B.; Gomes, H. R.; Imperio, G. E.; Bloise, F. F.; Kluck, G.; Atella, G.; Matthews, S.; Bloise, E.; Ortiga-Carvalho, T. M.
10.1101/2020.08.04.236745 — physiology — Posted on 2020-08-05
3775 Small molecule FGF23 inhibitors increase serum phosphate and improve skeletal abnormalities in Hyp mice
Xiao, Z.; Liu, J.; Liu, S.-H.; Petridis, L.; Cai, C.; Cao, L.; Wang, G.; Chin, A. L.; Cleveland, J. W.; Ikedionwu, M. O.; Carrick, J. D.; Smith, J. C.; Quarles, L. D.
10.1101/2020.08.04.236877 — pharmacology and toxicology — Posted on 2020-08-05
3779 CIVET-Macaque: an automated pipeline for MRI-based cortical surface generation and cortical thickness in macaques
Lepage, C.; Wagstyl, K.; Jung, B.; Seidlitz, J.; Sponheim, C.; Ungerleider, L.; Wang, X.; Evans, A. C.; Messinger, A.
10.1101/2020.08.04.237149 — neuroscience — Posted on 2020-08-05
3780 Plasmodium falciparum increases its investment in gametocytes in the wet season in asymptomatic individuals
Aduma, C. O.; Ogolla, S.; Atieli, H.; Ondigo, B. N.; Lee, M.-C.; Githeko, A.; Dent, A. E.; Kazura, J. W.; Yan, G.; Koepfli, C.
10.1101/2020.08.04.236950 — microbiology — Posted on 2020-08-05
3781 Immunosuppressive role of PGE2 during human tuberculosis
Pellegrini, J. M.; Tateosian, N. L.; Morelli, M. P.; Rolandelli, A.; Amiano, N. O.; Palmero, D. J.; Levi, A.; Ciallella, L.; Colombo, M. I.; Garcia, V. E.
10.1101/2020.08.04.236257 — immunology — Posted on 2020-08-05
3782 Characterization of extracellular vesicles and artificial nanoparticles with four orthogonal single-particle analysis platforms
Mallick, E. R.; Arab, T.; Huang, Y.; Dong, L.; Liao, Z.; Zhao, Z.; Smith, B.; Haughey, N. J.; Pienta, K. J.; Slusher, B. S.; Tarwater, P. M.; Tosar, J. P.; Zivkovic, A. M.; Vreeland, W. N.; Paulaitis, M. E.; Witwer, K. W.
10.1101/2020.08.04.237156 — cell biology — Posted on 2020-08-05
3785 Cortical thickness estimation in individuals with cerebral small vessel disease, focal atrophy, and chronic stroke lesions.
Ozzoude, M.; Ramirez, J.; Raamana, P. R.; Holmes, M. F.; Walker, K.; Scott, C. J. M.; Goubran, M.; Kwan, D.; Tartaglia, M. C.; Beaton, D.; Strother, S. C.; Symons, S.; Bartha, R.; Swartz, R. H.; Black, S. E.; on behalf of the ONDRI Investigators,
10.1101/2020.08.04.236760 — neuroscience — Posted on 2020-08-05
3786 Gut microbiome composition predicts summer core range size in a generalist and specialist ungulate
Wolf, J. F.; Kriss, K. D.; MacAulay, K. M.; Munro, K.; Patterson, B. R.; Shafer, A. B. A.
10.1101/2020.08.04.236638 — molecular biology — Posted on 2020-08-05
3788 Evidence for an extreme founding effect in a highly successful invasive species
Kratzer, K. V.; van der Marel, A.; Garroway, C. J.; Lopez-Darias, M.; Petersen, S. D.; Waterman, J. M.
10.1101/2020.08.04.236695 — evolutionary biology — Posted on 2020-08-05
3789 Current and future ocean chemistry negatively impacts calcification in predatory planktonic snails
Wall-Palmer, D.; Mekkes, L.; Ramos-Silva, P.; Daemmer, L. K.; Goetze, E.; Bakker, K.; Duijm, E.; Peijnenburg, K. T. C. A.
10.1101/2020.08.04.236166 — ecology — Posted on 2020-08-05
3790 Specific OCRL1 patient mutations differentially impact Lowe Syndrome cellular phenotypes
Ramadesikan, S.; Skiba, L.; Lee, J.; Madhivanan, K.; Sarkar, D.; De La Fuente, A.; Hanna, C. B.; Hazbun, T.; Kihara, D.; Aguilar, R. C.
10.1101/2020.08.04.236612 — cell biology — Posted on 2020-08-05
3792 The structural and functional connectivity neural underpinnings of body image
Moayedi, M.; Noroozbahari, N.; Hadjis, G.; Themelis, K.; Salomons, T. V.; Newport, R.; Lewis, J. S.
10.1101/2020.08.04.236547 — neuroscience — Posted on 2020-08-05
3793 Proteogenomic analysis unveils the HLA Class I presented immunopeptidome in melanoma and EGFR mutant lung adenocarcinoma
Qi, Y. A.; Maity, T. K.; Cultraro, C. M.; Misra, V.; Zhang, X.; Ade, C.; Gao, S.; Milewski, D.; Nguyen, K. D.; Ebrahimabadi, M. H.; Hanada, K.-i.; Khan, J.; Sahinalp, C.; Yang, J. C.; Guha, U.
10.1101/2020.08.04.236331 — immunology — Posted on 2020-08-05
3794 Assessing ambitious nature conservation strategies within a 2 degree warmer and food-secure world
Kok, M.; Meijer, J. R.; Zeist, W.-J. v.; Hilbers, J.; Immovilli, M.; Janse, J.; Stehfest, E.; Bakkenes, M.; Tabeau, A.; Schipper, A.; Alkemade, R.
10.1101/2020.08.04.236489 — ecology — Posted on 2020-08-05
3795 Towards A 3D Chromosome Shape Alphabet
Soto, C. J.; Bryner, D.; Neretti, N.; Srivastava, A.
10.1101/2020.08.04.236224 — bioinformatics — Posted on 2020-08-05
3796 A semi-automated method for measuring xylem vessel length distribution
Pereira, L.; Miranda, M.; Pires, G.; Pacheco, V.; Guan, X.; Kaack, L.; Machado, E.; Jansen, S.; Tyree, M.; Ribeiro, R.
10.1101/2020.08.04.234575 — plant biology — Posted on 2020-08-05
3800 Local increases in sleep-like activity predict the occurrence of emotion suppression failures
Avvenuti, G.; Bertelloni, D.; Lettieri, G.; Ricciardi, E.; Cecchetti, L.; Pietrini, P.; Bernardi, G.
10.1101/2020.08.04.235978 — neuroscience — Posted on 2020-08-05
3810 Accurate brain age prediction using recurrent slice-based networks
Lam, P. K.; Santhalingam, V.; Suresh, P.; Baboota, R.; Zhu, A. H.; Thomopoulos, S. I.; Jahanshad, N.; Thompson, P. M.
10.1101/2020.08.04.235069 — neuroscience — Posted on 2020-08-05
3811 Paradoxical relationships between active transport and global protein distributions in neurons
Bellotti, A.; Murphy, J. G.; Lin, L.; Petralia, R.; Wang, Y.-X.; Hoffman, D.; O'Leary, T.
10.1101/2020.08.05.238071 — neuroscience — Posted on 2020-08-05
3818 Accurate and interpretable prediction of poor health in small ruminants with accelerometers and machine learning
Montout, A. X.; Bhamber, R. S.; Lange, D. S.; Ndlovu, D. Z.; Morgan, E. R.; Ioannou, C. C.; Terrill, T. H.; Van Wyk, J. A.; Burghardt, T.; Dowsey, A. W.
10.1101/2020.08.03.234203 — animal behavior and cognition — Posted on 2020-08-04
3819 Pharmacological insights into safety and efficacy determinants for the development of adenosine receptor biased agonists in the treatment of heart failure
Rueda, P.; Merlin, J.; Chimenti, S.; Feletou, M.; Paysant, J.; White, P. J.; Christopoulos, A.; Sexton, P. M.; Summers, R. J.; Charman, W. N.; May, L. T.; Langmead, C. J.
10.1101/2020.07.22.215509 — pharmacology and toxicology — Posted on 2020-08-04
3820 JQ-1 ameliorates schistosomiasis liver fibrosis by suppressing JAK2 and STAT3 activation
Ding, H.; Tian, J.; Yang, X.; Ji, Y.; El-Ashram, S.; Hou, X.; Ren, C.; Shen, J.; Liu, M.
10.1101/2020.08.04.235812 — pharmacology and toxicology — Posted on 2020-08-04
3822 Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health
Strausz, S.; Ruotsalainen, S. E.; Ollila, H. M.; Karjalainen, J.; Reeve, M.; Kurki, M.; Mars, N.; Havulinna, A. S.; Kiiskinen, T.; Mansour Aly, D.; Ahlqvist, E.; Teder-Laving, M.; Palta, P.; Groop, L.; Magi, R.; Makitie, A.; Salomaa, V.; Bachour, A.; Tuomi, T.; Palotie, A.; Palotie, T.; Ripatti, S.
10.1101/2020.08.04.235994 — genetics — Posted on 2020-08-04
3827 Dietary Protein on Growth Performance, Serum Biochemical Index and offspring of Hu ewes in late pregnancy
Yang, H. s.; Wang, X.; Wang, Q.; Wang, Y.; Dai, C.; Li, J.; Huang, P.; Li, Y.; Ding, X.; Huang, J.; Hussain, T.; Yang, H.; Qiye Wang1,2, Yancan Wang, Chunpeng Dai2, Jianzhong Li1, Pengfei Huang1, Yali Li1, Xueqin Ding1, Jin,
10.1101/2020.08.04.235853 — physiology — Posted on 2020-08-04
3828 Cyrius: accurate CYP2D6 genotyping using whole genome sequencing data
Chen, X.; Shen, F.; Gonzaludo, N.; Malhotra, A.; Rogert, C.; Taft, R. J.; Bentley, D. R.; Eberle, M. A.
10.1101/2020.05.05.077966 — bioinformatics — Posted on 2020-08-04
3829 Elongation of Caudalized Human Organoids Mimics Neural Tube Development
Libby, A. R. G.; Joy, D. A.; Elder, N. H.; Bulger, E. A.; Krakora, M. Z.; Gaylord, E. A.; Mendoza-Camacho, F.; Butts, J. C.; McDevitt, T. C.
10.1101/2020.03.05.979732 — bioengineering — Posted on 2020-08-04
3833 Human vulnerability to cancer malignancy is enhanced by evolution of higher mesenchymal CD44 expression compared to other mammals
Ma, X.; Dighe, A.; Maziarz, J.; Neumann, E.; Erkenbrack, E.; Hei, Y.-Y.; Liu, Y.; Suhail, Y.; Kshitiz, K.; Pak, I.; Levchenko, A.; Wagner, G.
10.1101/2020.08.03.234617 — evolutionary biology — Posted on 2020-08-04
3840 Virtual Screening and Elucidation of Putative Binding Mode for Small Molecule Antagonist of BCL2 BH4 Domain
Joel, I. y.; Adigun, T. O.; AJIBOLA, A. O.; BANKOLE, O. O.; OZOJIOFOR, U. O.; REMI-ESAN, I. A.; SULAIMON, L. A.
10.1101/2020.07.29.226308 — bioinformatics — Posted on 2020-08-04
3841 A comprehensive benchmarking of WGS-based structural variant callers
Sarwal, V.; Niehus, S.; Ayyala, R.; Chang, S.; Lu, A.; Darci-Maher, N.; Littman, R.; Chhugani, K.; Soylev, A.; Comarova, Z.; Wesel, E.; Castellanos, J.; Chikka, R.; Distler, M. G.; Eskin, E.; Flint, J.; Mangul, S.
10.1101/2020.04.16.045120 — bioinformatics — Posted on 2020-08-04
3843 Retinal optic flow during natural locomotion
Matthis, J. S.; Muller, K. S.; Bonnen, K. L.; Hayhoe, M. M.
10.1101/2020.07.23.217893 — neuroscience — Posted on 2020-08-04
3845 Ventral Pallidum GABA Neurons Mediate Motivation Underlying Risky Choice
Farrell, M. R.; Esteban, J.; Faget, L.; Floresco, S. B.; Hnasko, T. S.; Mahler, S. V.
10.1101/2020.08.04.221960 — neuroscience — Posted on 2020-08-04
3855 Citrus vascular proteomics highlights the role of peroxidases and serine proteases during Huanglongbing disease progression
Franco, J.; Thapa, S. P.; Pang, Z.; Gurung, F. B.; Liebrand, T. W.; Stevens, D. M.; Ancona, V.; Wang, N.; Coaker, G.
10.1101/2020.04.05.025718 — plant biology — Posted on 2020-08-04
3856 Not out of the box: phylogeny of the broadly sampled Buxaceae
Shipunov, A.; Lee, H. J.; Choi, J.; Pay, K.; DeSpiegelaire, S.; Floden, A.
10.1101/2020.08.03.235267 — plant biology — Posted on 2020-08-04
3863 Sexually dimorphic development of depression-related brain networks during healthy human adolescence
Dorfschmidt, L.; Bethlehem, R. A. I.; Seidlitz, J.; Vasa, F.; White, S. R.; Romero-Garcia, R.; Kitzbichler, M. G.; Aruldass, A.; Morgan, S. E.; Goodyer, I. M.; Fonagy, P.; Jones, P. B.; Dolan, R. J.; the NSPN Consortium, ; Harrison, N. A.; Vertes, P. E.; Bullmore, E. T.
10.1101/2020.07.06.184473 — neuroscience — Posted on 2020-08-04
3864 Bacteriophage deficiency characterizes respiratory virome dysbiosis in childhood asthma
Megremis, S.; Constantinides, B.; Xepapadaki, P.; Bachert, C.; Neurath-Finotto, S.; Jartti, T.; Kowalski, M. L.; Sotiropoulos, A. G.; Tapinos, A.; Vuorinen, T.; Andreakos, E.; Robertson, D. L.; Papadopoulos, N. G.
10.1101/2020.08.04.236067 — microbiology — Posted on 2020-08-04
3865 Old drugs with new tricks: Efficacy of fluoroquinolones to suppress replication of flaviviruses
Scroggs, S. L. P.; Andrade, C. C.; Chinnasamy, R.; Azar, S. R.; Schirtzinger, E. E.; Garcia, E. I.; Arterburn, J. B.; Hanley, K. A.; Rossi, S. L.
10.1101/2020.03.30.016022 — microbiology — Posted on 2020-08-04
3868 Inflammasome- and gasdermin D-independent IL-1β production mobilizes neutrophils to inhibit antitumor immunity
Kiss, M.; Vande Walle, L.; Lebegge, E.; Van Damme, H.; Murgaski, A.; Qian, J.; Ehling, M.; Pretto, S.; Bolli, E.; Keirsse, J.; Elkrim, Y.; Martins, M. S.; Fossoul, A.; Lambrechts, D.; Mazzone, M.; Wullaert, A.; Lamkanfi, M.; Van Ginderachter, J. A.; Laoui, D.
10.1101/2020.08.04.235796 — immunology — Posted on 2020-08-04
3869 Genome-wide study of the effect of blood collection tubes on the cell-free DNA methylome
Van Paemel, R.; De Koker, A.; Caggiano, C.; Morlion, A.; Mestdagh, P.; De Wilde, B.; Vandesompele, J.; De Preter, K.
10.1101/2020.04.23.055293 — genomics — Posted on 2020-08-04
3870 A genomic dating tool for ancient genomes resolves the origins of hundreds of Eurasian genomes
Esposito, U.; Holland, G.; Alshehab, G.; Dobre, A. M.; Pirooznia, M.; Brimacombe, C.; Elhaik, E.
10.1101/828962 — genomics — Posted on 2020-08-04
3871 Genetic background modifies vulnerability to glaucoma related phenotypes in Lmx1b mutant mice
Tolman, N.; Macalinao, D.; Kearney, A.; Macnicoll, K.; Montgomery, C.; de Vries, W.; Jackson, I.; Cross, S. H.; Kizhatil, K.; Nair, S.; John, S.
10.1101/2020.07.05.188516 — genetics — Posted on 2020-08-04
3872 TREM2 R47H exacerbates immune response in Alzheimer's disease brain
Korvatska, O.; Kiianitsa, K.; Ratushny, A.; Matsushita, M.; Beeman, N.; Chien, W.-M.; Satoh, J.-I.; Dorschner, M. O.; Keene, C. D.; Bammler, T. K.; Bird, T. D.; Raskind, W. H.
10.1101/499319 — genetics — Posted on 2020-08-04
3874 Estimating individual level plant traits at scale
Marconi, S.; Graves, S.; Weinstein, B.; Bohlman, S.; White, E.
10.1101/556472 — ecology — Posted on 2020-08-04
3875 An immobilization technique for long-term time-lapse imaging of explanted Drosophila tissues
Bostock, M. P.; Prasad, A. R.; Chaouni, R.; Yuen, A. C.; Sousa-Nunes, R.; Amoyel, M.; Fernandes, V. M.
10.1101/2020.08.04.234864 — developmental biology — Posted on 2020-08-04
3877 Improving Landsat predictions of rangeland fractional cover with multitask learning and uncertainty
Allred, B. W.; Bestelmeyer, B. T.; Boyd, C. S.; Brown, C.; Davies, K. W.; Ellsworth, L. M.; Erickson, T. A.; Fuhlendorf, S. D.; Griffiths, T. V.; Jansen, V.; Jones, M. O.; Karl, J.; Maestas, J. D.; Maynard, J. J.; McCord, S. E.; Naugle, D. E.; Starns, H. D.; Twidwell, D.; Uden, D. R.
10.1101/2020.06.10.142489 — ecology — Posted on 2020-08-04
3878 Mitigation of radiation damage in macromolecules via tunable ultrafast stroboscopic TEM
Choe, H.; Ponomarev, I.; Montgomery, E.; Lau, J. W.; Zhu, Y.; Zhao, Y.; Liu, A.; Kanareykin, A.; Jing, C.
10.1101/2020.05.15.099036 — biophysics — Posted on 2020-08-04
3880 The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS-mTOR signaling and vascular function
Alghanem, A. F.; Ta, C.; Maurer, J. M.; Gunasekar, S. K.; Kumar, A.; Fatima, U.; Kang, C.; Xie, L.; Adeola, O.; Abello, J.; Riker, M.; Elliot-Hudson, M.; Minerath, R. A.; Stratman, A.; Grueter, C. E.; Mullins, R. F.; Sah, R.
10.1101/2020.08.04.236182 — cell biology — Posted on 2020-08-04
3884 Transmission and genetic adaptation of Achromobacter in cystic fibrosis
Gabrielaite, M.; Norskov-Lauritsen, N.; Nielsen, F. C.; Johansen, H. K.; Marvig, R. L.
10.1101/2020.08.04.235952 — genomics — Posted on 2020-08-04
3887 Environmental enrichment reverses memory impairment in B3-ARKO mice
Ravache, T. T.; Nunes, G. G.; Batistuzzo, A.; Lorena, F. B.; do Nascimento, B. P. P.; Bernardi, M.; Ribeiro, M. O.
10.1101/2020.08.04.234849 — neuroscience — Posted on 2020-08-04
3889 First report of antiviral activity of nordihydroguaiaretic acid against Fort Sherman-like virus (Orthobunyavirus)
Martinez, F.; Mugas, M. L.; Aguilar, J. J.; Marioni, J.; Contigiani, M. S.; Nunez Montota, S. C.; Konigheim, B. S.
10.1101/2020.08.04.236133 — microbiology — Posted on 2020-08-04
3896 Transient Room Lighting for Ambient Light Multiphoton Microscopy
Velten, A.; Uselmann, A. J.; Prajapati, S.; Bredfeldt, J. S.; Mackie, T. R.; Eliceiri, K. W.
10.1101/2020.08.04.236364 — bioengineering — Posted on 2020-08-04
3897 SCV-2000bp: a primer panel for SARS-CoV-2 full-genome sequencing
Speranskaya, A.; Kaptelova, V.; Valdokhina, A.; Bulanenko, V.; Samoilov, A.; Korneenko, E.; Shipulina, O.; Akimkin, V.
10.1101/2020.08.04.234880 — molecular biology — Posted on 2020-08-04
3898 A valid protective immune response elicited in rhesus macaques by an inactivated vaccine is capable of defending against SARS-CoV-2 infection
Chen, H.; Xie, Z.; Long, R.; Fan, S.; Li, H.; He, Z.; Xu, K.; Liao, Y.; Wang, L.; Zhang, Y.; Li, X.; Dong, X.; Mou, T.; Zhou, X.; Yang, Y.; Guo, L.; Yang, J.; Zheng, H.; Xu, X.; Li, J.; Liang, Y.; Li, D.; Zhao, Z.; Hong, C.; Zhao, H.; Jiang, G.; Che, Y.; Yang, F.; Hu, Y.; Wang, X.; Pu, J.; Ma, K.; Wang, L.; Chen, C.; Duan, W.; Shen, D.; Zhao, H.; Jiang, R.; Deng, X.; Li, Y.; Zhu, H.; Zhou, J.; Yu, L.; Xu, M.; Yang, H.; Yi, L.; Zhou, Z.; Yang, J.; Duan, N.; Yang, H.; Zhao, W.; Yang, W.; Li, C.; Liu, L.; Li, Q.
10.1101/2020.08.04.235747 — immunology — Posted on 2020-08-04
3899 A distinct innate immune signature marks progression from mild to severe COVID-19
Chevrier, S.; Zurbuchen, Y.; Cervia, C.; Adamo, S.; Raeber, M. E.; de Souza, N.; Sivapatham, S.; Jacobs, A.; Bächli, E.; Rudiger, A.; Stüssi-Helbling, M.; Huber, L. C.; Schaer, D. J.; Nilsson, J.; Boyman, O.; Bodenmiller, B.
10.1101/2020.08.04.236315 — immunology — Posted on 2020-08-04
3900 Lymphopenia-induced T cell proliferation is a hallmark of severe COVID-19
Adamo, S.; Chevrier, S.; Cervia, C.; Zurbuchen, Y.; Räber, M. E.; Yang, L.; Sivapatham, S.; Jacobs, A.; Bächli, E.; Rudiger, A.; Stüssi-Helbling, M.; Huber, L. C.; Schaer, D.; Bodenmiller, B.; Boyman, O.; Nilsson, J.
10.1101/2020.08.04.236521 — immunology — Posted on 2020-08-04
3903 SARS-CoV-2 genome analysis of strains in Pakistan reveals GH, S and L clade strains at the start of the pandemic
Ghanchi, N. K.; Masood, K. I.; Nasir, A.; Khan, W.; Abidi, S. H.; Shahid, S.; Mahmood, S. F.; Kanji, A. R.; Razzak, S. A.; Ansar, Z.; Islam, N.; Dharejo, M. B.; Hasan, Z.; Hasan, R.
10.1101/2020.08.04.234153 — genomics — Posted on 2020-08-04
3906 SARS-CoV-2 suppresses mRNA expression of selenoproteins associated with ferroptosis, ER stress and DNA synthesis
Wang, Y.; Huang, J.; Sun, Y.; He, J.; Li, W.; Liu, Z.; Taylor, E. W.; Rayman, M. P.; Wan, X.; Zhang, J.
10.1101/2020.07.31.230243 — microbiology — Posted on 2020-08-04
3907 Study on β-Chitosan against the binding of SARS-CoV-2S-RBD/ACE2
Alitongbieke, G.; Li, X.-M.; Wu, Q.-C.; Lin, Z.-C.; Huang, J.-F.; Xue, Y.; Liu, J.-N.; Lin, J.-M.; Pan, T.; Chen, Y.-X.; Su, Y.; Zhang, G.-G.; Leng, B.; Liu, S.-W.; Pan, Y.-T.
10.1101/2020.07.31.229781 — biochemistry — Posted on 2020-08-04
3908 SARS-CoV-2 infection, disease and transmission in domestic cats
Gaudreault, N. N.; Trujillo, J. D.; Carossino, M.; Meekins, D. A.; Morozov, I.; Madden, D. W.; Indran, S. V.; Bold, D.; Balaraman, V.; Kwon, T.; Libanori Artiaga, B.; Cool, K.; Garcia-Sastre, A.; Ma, W.; Wilson, W. C.; Henningson, J.; Balasuriya, U. B.; Richt, J. A.
10.1101/2020.08.04.235002 — microbiology — Posted on 2020-08-04
3909 KRASG12D mutant cells are outcompeted by wild type neighbours in adult pancreas in an EPHA2-dependent manner.
Hill, W.; Zaragkoulias, A.; Salvador, B.; Parfitt, G.; Alatsatianos, M.; Padilha, A.; Porazinski, S.; Woolley, T. E.; Morton, J. P.; Sansom, O. J.; Hogan, C.
10.1101/2020.08.04.231050 — cell biology — Posted on 2020-08-04
3910 Komenti: A semantic text mining framework
Slater, L. T.; Bradlow, W.; Hoehndorf, R.; Motti, D. F.; Ball, S.; Gkoutos, G. V.
10.1101/2020.08.04.233049 — bioinformatics — Posted on 2020-08-04
3916 Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors
Iketani, S.; Forouhar, F.; Liu, H.; Hong, S. J.; Lin, F.-Y.; Nair, M. S.; Zask, A.; Huang, Y.; Xing, L.; Stockwell, B. R.; Chavez, A.; Ho, D. D.
10.1101/2020.08.03.235291 — microbiology — Posted on 2020-08-04
3917 Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysis
Bull, R. A.; Adikari, T.; Hammond, J. M.; Stevanovski, I.; Ferguson, J. M.; Beukers, A. G.; Naing, Z.; Yeang, M.; Verich, A.; Gamaarachichi, H.; Kim, K. W.; Luciani, F.; Stelzer-Braid, S.; Eden, J.-S.; Rawlinson, W. D.; van Hal, S. J.; Deveson, I. W.
10.1101/2020.08.04.236893 — genomics — Posted on 2020-08-04
3919 KDM4 Orchestrates Epigenomic Remodeling of Senescent Cells and Potentiates the Senescence-Associated Secretory Phenotype
Zhang, B.; Long, Q.; Wu, S.; Song, S.; Xu, Q.; Han, L.; Qian, M.; Ren, X.; Jiang, J.; Fu, Q.; Guo, J.; Zhang, X.; Chang, X.; Lam, E.; Campisi, J.; Kirkland, J.; Sun, Y.
10.1101/2020.08.03.235465 — cell biology — Posted on 2020-08-04
3921 Hypertonic saline solution inhibits SARS-CoV-2 in vitro assay
Machado, R. R. G.; Glaser, T.; Araujo, D. B.; Petiz, L. L.; Oliveira, D. B. L.; Durigon, G. S.; Leal, A. L.; Pinho, J. R. R.; Ferreira, L. C. S.; Ulrich, H.; Durigon, E. L. R.; Guzzo, C. R.
10.1101/2020.08.04.235549 — microbiology — Posted on 2020-08-04
3925 Cytidine monophosphate N-acetylneuraminic acid synthetase and solute carrier family 35 member A1 are required for reovirus binding and infection
Urbanek, K.; Sutherland, D. M.; Orchard, R. C.; Wilen, C. B.; Knowlton, J. J.; Aravamudhan, P.; Taylor, G. M.; Virgin, H. W.; Dermody, T. S.
10.1101/2020.08.03.235572 — molecular biology — Posted on 2020-08-04
3927 Japonica Array NEO with increased genome-wide coverage and abundant disease risk SNPs
Sakurai-Yageta, M.; Kumada, K.; Gocho, C.; Makino, S.; Uruno, A.; Tadaka, S.; Motoike, I. N.; Kimura, M.; Ito, S.; Otsuki, A.; Narita, A.; Kudo, H.; Aoki, Y.; Danjoh, I.; Yasuda, J.; Kawame, H.; Minegishi, N.; Koshiba, S.; Fuse, N.; Tamiya, G.; Yamamoto, M.; Kinoshita, K.
10.1101/2020.08.03.235226 — genomics — Posted on 2020-08-04
3928 Spatial tissue profiling by imaging-free molecular tomography
Schede, H. H.; Schneider, C. G.; Stergiadou, J.; Borm, L. E.; Ranjak, A.; Yamawaki, T. M.; David, F. P. A.; Lonnerberg, P.; Laurent, G.; Tosches, M. A.; Codeluppi, S.; La Manno, G.
10.1101/2020.08.04.235655 — genomics — Posted on 2020-08-04
3931 Membrane Orientation and Oligomerization of the Melanocortin Receptor Accessory Protein 2
Chen, V.; Bruno, A. E.; Britt, L. L.; Hernandez, C. Q.; Gimenez, L. E.; Peisley, A.; Cone, R. D.; Millhauser, G. L.
10.1101/2020.08.03.235200 — biochemistry — Posted on 2020-08-04
3932 L-DOPA dioxygenase of the fly agaric toadstool: revision of the dodA gene sequence and mechanism of enzymatic pigment production
Soares, D. M. M.; Goncalves, L. C. P.; Machado, C. O.; Esteves, L. C.; Stevani, C. V.; Oliveira, C. C.; Dorr, F. A.; Pinto, E.; Adachi, F. M. M.; Hotta, C. T.; Bastos, E. L.
10.1101/2020.08.03.235077 — biochemistry — Posted on 2020-08-04
3935 Insights into dispersed duplications and complex structural mutations from whole genome sequencing 706 families
Whelan, C. W.; Handsaker, R. E.; Genovese, G.; Kashin, S.; Lek, M.; Hughes, J.; McElwee, J.; Lenardo, M.; MacArthur, D.; McCarroll, S. A.
10.1101/2020.08.03.235358 — genomics — Posted on 2020-08-04
3936 Divergent use of metabolic fluxes in breast cancer metastasis
Mathur, D.; Liao, C.; La Ferlita, A.; Alaimo, S.; Ferro, A.; Xavier, J.
10.1101/2020.08.03.234468 — cancer biology — Posted on 2020-08-04
3937 Human Cytomegalovirus Drives WDR5 to the Virion Assembly Compartment to Facilitate Virion Assembly
Luo, M.-H.; Yang, B.; Yao, Y.; Wu, H.; Yang, H.; Ma, X.-H.; Li, D.; Wang, X.-Z.; Huang, S.-N.; Jiang, X.; Cheng, S.; Sun, J.-Y.; Huang, Z.-L.; Zhao, C.; McVoy, M. A.; Ahn, J.-H.; Zeng, W.-B.; Britt, W. J.; Gong, S.
10.1101/2020.08.03.235630 — pathology — Posted on 2020-08-04
3938 TuMV triggers stomatal closure but reduces drought tolerance in Arabidopsis
Manacorda, C. A.; Gudesblat, G.; Sutka, M.; Alemano, S.; Peluso, F.; Oricchio, P.; Baroli, I.; asurmendi, s.
10.1101/2020.08.03.235234 — molecular biology — Posted on 2020-08-04
3941 Genome-Wide Screening Reveals CSDE1 as a Novel Regulator of the LDL Receptor
Smith, G. A.; Pampana, A.; Natarajan, P.; Shokat, K.; Chorba, J. S.
10.1101/2020.08.03.235028 — genomics — Posted on 2020-08-04
3945 Machine Learning-Based Protein Microarray Digital Assay Analysis
Song, Y.; Zhao, J.; Cai, T.; Su, S.-H.; Sandford, E.; Flora, C.; Singer, B. H.; Ghosh, M.; Choi, S. W.; Tewari, M.; Kurabayashi, K.
10.1101/2020.08.04.236448 — bioengineering — Posted on 2020-08-04
3947 A Multi-Gene Synaptic Plasticity Array Identifies Candidate Molecular Underpinnings Of Cognitive And Mood Deficits In Rats With Heart Failure
Parent, M. B.; Ferreira-Neto, H. C.; Kruemmel, A. R.; Althammer, F.; Patel, A. A.; Keo, S.; Whitley, K. E.; Cox, D. N.; Stern, J. E.
10.1101/2020.08.03.234831 — neuroscience — Posted on 2020-08-04
3949 Developing Cyclic Peptomers as Broad-Spectrum Gram negative Bacterial Type III Secretion System Inhibitors
Lam, H.; Lau, T.; Lentz, A.; Sherry, J.; Cabrera-Cortez, A.; Hug, K.; Engel, J.; Lokey, S.; Auerbach Stone, V.
10.1101/2020.08.03.235622 — microbiology — Posted on 2020-08-04
3950 Intestinal infection results in impaired lung innate immunity to secondary respiratory infection.
Trivedi, S.; Grossmann, A. H.; Jensen, O.; Cody, M. J.; Warren, K. J.; Yost, C. C.; Leung, D. T.
10.1101/2020.08.03.235457 — immunology — Posted on 2020-08-04
3955 Oxygen-independent chemogenetic protein tags for live-cell fluorescence microscopy
Iyer, A.; Baranov, M.; Foster, A. J.; Chordia, S.; Roelfes, G.; van den Bogaart, G.; Poolman, B.
10.1101/2020.08.03.234815 — biochemistry — Posted on 2020-08-04
3958 Italian Odonates in the Pandora's Box: A Comprehensive DNA Barcoding Inventory Shows Taxonomic Warnings at the Holarctic Scale
Galimberti, A.; Assandri, G.; Maggioni, D.; Ramazzotti, F.; Baroni, D.; Bazzi, G.; Chiandetti, I.; Corso, A.; Ferri, V.; Galuppi, M.; Ilahiane, L.; La Porta, G.; Lorenzo, L.; Landi, F.; Mastropasqua, F.; Ramellini, S.; Santinelli, R.; Soldato, G.; Surdo, S.; Casiraghi, M.
10.1101/2020.04.23.056911 — zoology — Posted on 2020-08-04
3963 A biased adenosine A1R agonist elicits analgesia without cardiorespiratory depression
Wall, M.; Hill, E.; Huckstepp, R.; Barkan, K.; Deganutti, G.; Leuenberger, M.; Preti, B.; Winfield, I.; Wei, H.; Imlach, W.; Dean, E.; Hume, C.; Hayward, S.; Oliver, J.; Zhao, F.-Y.; Spanswick, D.; Reynolds, C. A.; Lochner, M.; Ladds, G.; Frenguelli, B.
10.1101/2020.04.04.023945 — physiology — Posted on 2020-08-04
3965 Enhancing Intracellular Accumulation and Target Engagement of PROTACs with Reversible Covalent Chemistry
Guo, W.-H.; Qi, X.; Yu, X.; Liu, Y.; Chung, C.-I.; Bai, F.; Lin, X.; Lu, D.; Wang, L.; Chen, J.; Su, L.; Nomie, K. J.; Li, F.; Wang, M. C.; Shu, X.; Onuchic, J. N.; Woyach, J. A.; Wang, M. L.; Wang, J.
10.1101/2019.12.30.873588 — pharmacology and toxicology — Posted on 2020-08-04
3966 SK3-overexpression drives sex-dimorphic working and social memory impairment in mice.
Campos, A. C.; Scarante, F. F.; Martin, S.; Lazzarin, M.; Hermes, D.; De Souza-Silva, M. A.; Sanchez, A.; Pardo, L. A.; Stühmer, W.; Del-Bel, E. A.
10.1101/2020.07.31.230656 — neuroscience — Posted on 2020-08-04
3967 Astroglia in lateral habenula is essential for antidepressant efficacy of light
Delcourte, S.; Etievant, A.; Rovera, R.; Mor, D.; Cooper, H. M.; Le, H. D.; Williams, A. E.; Panda, S.; Azmani, R.; Raineteau, O.; Coutanson, C.; Dkhissi-Benyahya, O.; Haddjeri, N.
10.1101/2020.07.31.230201 — neuroscience — Posted on 2020-08-04
3973 Visual Perception in the Periphery: The Role of Covert Attention Vectors in the Extraction of Semantic Information
Suri, I.; Wilson, P. M.; Doustmohammadi, S.; De Schutter, A.; Chunwatanapong, T. S.; Tan, J.; Varadharajulu, S. D.; O'Connell, N. H.; Lai, A.; Dureja, S.; Govin, R. J. P.; Arisaka, K.; Mills, E. A. F.
10.1101/2020.08.02.231803 — neuroscience — Posted on 2020-08-04
3977 Greater TMS-evoked frontoparietal effective connectivity is correlated with better cognitive performance
Morris, T. P.; Redondo-Camos, M.; Cattaneo, G.; Macia, D.; Solana_Sanchez, J.; Espana-Irla, G.; Delgado-Galen, S.; Alviarez-Schulze, V.; Pachon Garcia, C.; Santarnecchi, E.; Tadayon, E.; Ozdemir, R.; Tormos-Munoz, J. M.; Bartres-Faz, D.; Pascual-Leone, A.; Shafi, M.
10.1101/2020.08.03.234518 — neuroscience — Posted on 2020-08-04
3982 Non-canonical, potassium-driven cerebrospinal fluid clearance
Xu, H.; Fame, R. M.; Sadegh, C.; Sutin, J.; Naranjo, C.; Syau, D.; Cui, J.; Shipley, F. B.; Vernon, A.; Gao, F.; Zhang, Y.; Holtzman, M. J.; Heiman, M.; Warf, B. C.; Lin, P.-Y.; Lehtinen, M. K.
10.1101/2020.08.03.234260 — neuroscience — Posted on 2020-08-04
3986 Induction of core symptoms of autism spectrum disorders by in vivo CRISPR/Cas9-based gene editing in the brain of adolescent rhesus monkeys
Shihao, W.; Xiao, L.; Dongdong, Q.; Linheng, Z.; Tian-Lin, C.; Zhifang, C.; Binbin, N.; Xiaofeng, R.; Jing, W.; Wenchao, W.; Yingzhou, H.; Yilin, G.; Longbao, L.; Yong, Y.; Xintian, H.; Zilong, Q.
10.1101/2020.08.03.233437 — neuroscience — Posted on 2020-08-04
3987 How do zebrafish respond to MK-801 and amphetamine? Relevance for assessing schizophrenia-relevant endophenotypes in alternative model organisms
Benvenutti, R.; Gallas-Lopes, M.; Sachett, A.; Marcon, M.; Strogulski, N. R.; Reis, C. G.; Chitolina, R.; Piato, A.; Herrmann, A. P.
10.1101/2020.08.03.234567 — neuroscience — Posted on 2020-08-04
3988 Brain Network Mechanisms of Visual Shape Completion
Keane, B. P.; Barch, D. M.; Mill, R.; Silverstein, S. M.; Krekelberg, B.; Cole, M. W.
10.1101/2020.08.03.233403 — neuroscience — Posted on 2020-08-04
3991 The human liver microenvironment shapes the homing and function of CD4+ T-cell populations
Wiggins, B. G.; Pallett, L. J.; Li, X.; Davies, S. P.; Amin, O. E.; Gill, U. S.; Patel, A. M.; Aliazis, K.; Liu, Y. S.; Reynolds, G. M.; Hirschfield, G.; Kennedy, P. F.; Huang, Y.; Maini, M. M.; Stamataki, Z.
10.1101/2020.08.03.230953 — immunology — Posted on 2020-08-04
3992 Phylogenomic analysis of SARS-CoV-2 genomes from western India reveals unique linked mutations
Paul, D.; Jani, K.; Kumar, J.; Chauhan, R.; Seshadri, V.; Lal, G.; Karyakarte, R.; Joshi, S.; Tambe, M.; Sen, S.; Karade, S.; Anand, K. B.; Shergill, S. P. S.; Gupta, R. M.; Bhat, M. K.; Sahu, A.; Shouche, Y. S.
10.1101/2020.07.30.228460 — genomics — Posted on 2020-08-04
3996 Engineered ACE2 receptor traps potently neutralize SARS-CoV-2
Glasgow, A.; Glasgow, J. E.; Limonta, D.; Solomon, P.; Lui, I.; Zhang, Y.; Nix, M. A.; Rettko, N. J.; Lim, S. A.; Zha, S.; Yamin, R.; Kao, K.; Rosenberg, O. S.; Ravetch, J. V.; Wiita, A. P.; Leung, K. K.; Zhou, X. X.; Hobman, T. C.; Kortemme, T. K.; Wells, J. A.
10.1101/2020.07.31.231746 — bioengineering — Posted on 2020-08-04
4002 High-precision protein-tracking with interferometric scattering microscopy
Taylor, R. W.; Holler, C.; Gholami Mahmoodabadi, R.; Küppers, M.; Mirzaalian Dastjerdi, H.; Zaburdaev, V.; Schambony, A.; Sandoghdar, V.
10.1101/2020.08.03.234773 — biophysics — Posted on 2020-08-04
4003 Ten Genetic Loci Identified for Milk Yield, Fat, and Protein in Holstein Cattle
Liu, L.; Zhou, J.; Chen, C. J.; Zhang, J.; Wen, W.; Tian, J.; Zhang, Z.; Gu, Y.
10.1101/2020.06.17.158386 — genomics — Posted on 2020-08-04
4005 Evidence for boundary layer oxygen diffusion limitation as a key driver of asteroid wasting
Aquino, C. A.; Besemer, R. M.; DeRito, C. M.; Kocian, J.; Porter, I. R.; Raimondi, P.; Rede, J. E.; Schiebelhut, L. M.; Sparks, J. P.; Wares, J. P.; Hewson, I. H.
10.1101/2020.07.31.231365 — ecology — Posted on 2020-08-04
4008 Climate-risk to European fisheries and coastal communities
Payne, M. R.; Kudahl, M.; Engelhard, G. H.; Peck, M. A.; Pinnegar, J. K.
10.1101/2020.08.03.234401 — ecology — Posted on 2020-08-04
4010 Exploring the boundaries of microbial habitability in soil
Dragone, N. B.; Diaz, M. A.; Hogg, I.; Lyons, W. B.; Jackson, W. A.; Wall, D. H.; Adams, B. J.; Fierer, N. B.
10.1101/2020.08.03.234583 — ecology — Posted on 2020-08-04
4015 GigaSOM.jl: High-perfomance clustering and visualization of huge cytometry datasets
Kratochvil, M.; Hunewald, O.; Heirendt, L.; Verissimo, V.; Vondrasek, J.; Satagopam, V. P.; Schneider, R.; Trefois, C.; Ollert, M.
10.1101/2020.08.03.234187 — bioinformatics — Posted on 2020-08-04
4020 Real time monitoring of peptidoglycan synthesis by membrane-reconstituted penicillin binding proteins
Vollmer, W.; Hernandez-Rocamora, V. M.; Baranova, N.; Peters, K.; Breukink, E.; Loose, M.
10.1101/2020.08.02.233189 — biochemistry — Posted on 2020-08-04
4022 Accurate and interpretable prediction of poor health in small ruminants with accelerometers and machine learning
Montout, A. X.; Bhamber, R. S.; Lange, D. S.; Ndlovu, D. Z.; Morgan, E. R.; Ioannou, C. C.; Terrill, T. H.; Van Wyk, J. A.; Burghardt, T.; Dowsey, A. W.
10.1101/2020.08.03.234203 — animal behavior and cognition — Posted on 2020-08-04
4024 Central and peripheral GLP-1 systems independently and additively suppress eating
Brierley, D. I.; Holt, M. K.; Singh, A.; de Araujo, A.; Vergana, M.; Afaghani, M.; Lee, S. J.; Scott, K.; Langhans, W.; Krause, E.; de Kloet, A.; Gribble, F.; Reimann, F.; Rinaman, L.; De Lartigue, G.; Trapp, S.
10.1101/2020.08.03.234427 — neuroscience — Posted on 2020-08-04
4025 Winners and losers over 35 years of dragonfly and damselfly distributional change in Germany
Bowler, D.; Eichenberg, D.; Conze, K.-J.; Suhling, F.; Baumann, K.; Boensel, A.; Bittner, T.; Drews, A.; Guenther, A.; Isaac, N.; Petzold, F.; Seyring, M.; Spengler, T.; Trockur, B.; Willigalla, C.; Bruelheide, H.; Jansen, F.; Bonn, A.
10.1101/2020.08.03.234104 — ecology — Posted on 2020-08-04
4026 Differential brain atrophy and neurogenetic profiles in cognitively-defined Alzheimer's disease subgroups
Groot, C.; Grothe, M. J.; Mukherjee, S.; Jelistratova, I.; Jansen, I.; van Loenhoud, A. C.; Risacher, S. L.; Saykin, A. J.; Mac Donald, C. L.; Mez, J.; Trittschuh, E. H.; Gryglewski, G.; Lanzenberger, R.; Pijnenburg, Y. A. L.; Barkhof, F.; Scheltens, P.; van der Flier, W. M.; Crane, P. K.; Ossenkoppele, R.
10.1101/2020.08.04.235762 — neuroscience — Posted on 2020-08-04
4028 X-chromosome upregulation is dynamically linked to the X-inactivation state
Lentini, A.; Coucoravas, C.; Andrews, N.; Enge, M.; Deng, Q.; Reinius, B.
10.1101/2020.07.06.189787 — cell biology — Posted on 2020-08-04
4037 Antidiabetic drug therapy alleviates type 1 diabetes in mice by promoting pancreatic alpha-cell transdifferentiation
Sarnobat, D.; Moffett, C. R.; Tanday, N.; Reimann, F.; Gribble, F. M.; Flatt, P. R.; Tarasov, A. I.
10.1101/2020.08.03.234070 — physiology — Posted on 2020-08-04
4038 Technological Properties Of Milk For Cheese Making With The Use Of Antioxidants In Diets For Cows With Subtoxic Dose Of Nitrates
Kokaeva, M.; Temiraev, R.; Chabaev, M.; Nekrasov, R.; Tsis, E. Y.; Kairov, V.; Nikkolova, B.; Edigova, S.; Konokova, B.
10.1101/2020.08.02.232660 — physiology — Posted on 2020-08-04
4039 TractoFlow-ABS (Atlas-Based Segmentation)
Theaud, G.; Houde, J.-C.; Bore, A.; Rheault, F.; Morency, F.; Descoteaux, M.
10.1101/2020.08.03.197384 — neuroscience — Posted on 2020-08-04
4040 Novel therapeutic targets to mitigate early neuronal dysfunction and cognitive deficits in tauopathy
Koren, S. A.; Hamm, M. J.; Cloyd, R.; Fontaine, S. N.; Chishti, E.; Lanzillotta, C.; Di Domenico, F.; Seyfried, N.; Duong, D.; Powell, D. K.; Vandsburger, M.; Hartz, A. M. S.; Koren, J.; Axten, J. M.; Laping, N. J.; Abisambra, J. F.
10.1101/2020.07.31.229583 — neuroscience — Posted on 2020-08-04
4041 The RNA phosphatase PIR-1 regulates endogenous small RNA pathways in C. elegans
Chaves, D. A.; Hui, D.; Li, L.; Moresco, J. J.; Oh, M. E.; Conte, D.; Yates, J. R.; Mello, C. C.; Gu, W.
10.1101/2020.08.03.235143 — molecular biology — Posted on 2020-08-04
4045 A novel Organ-Chip system emulates three-dimensional architecture of the human epithelia and allows fine control of mechanical forces acting on it.
VARONE, A.; Nguyen, J. K.; Leng, L.; Barrile, R.; Sliz, J.; Lucchesi, C.; Wen, N.; Gravanis, A.; Hamilton, G. A.; Karalis, K. C.; Hinojosa, C. D.
10.1101/2020.08.02.233338 — bioengineering — Posted on 2020-08-04
4046 The Effects Of Heavy Metals On The Morphological And Biochemical Composition Of The Blood Of Young Cattle Taking Into Account Of Breed Features
Temiraev, R.; Yuldashbaev, Y.; Cherchesova, S.; Lamarton, S.; Gappoeva, V.; Kairov, V.; Doeva, A.; Kalabekov, A.; Kornoukhova, I.
10.1101/2020.08.02.232694 — biochemistry — Posted on 2020-08-04
4047 Self-powered piezo-bioelectronic device mediates tendon repair through modulation of mechanosensitive ion channels.
Fernandez-Yague, M. A.; Trotier, A.; Akogwu Abbah, A.; Larrañaga, A.; Thirumaran, A.; Stapleton, A.; Tofail, S. A. M.; Palma, M.; Pandit, A.; Biggs, M. J.
10.1101/2020.08.03.227868 — bioengineering — Posted on 2020-08-04
4048 A nonsense mutation of bone morphogenetic protein-15 (BMP15) causes both infertility and increased litter size in pigs.
Flossmann, G.; Wurmser, C.; Pausch, H.; Tenghe, A.; Dodenhoff, J.; Dahinten, G.; Goetz, K.-U.; Russ, I.; Fries, H.-R.
10.1101/2020.08.03.222521 — genomics — Posted on 2020-08-03
4049 Comparative genomics and community curation further improve gene annotations in the nematode Pristionchus pacificus
Athanasouli, M.; Witte, H.; Weiler, C.; Loschko, T.; Eberhardt, G.; Sommer, R. J.; Rödelsperger, C.
10.1101/2020.08.03.233726 — genomics — Posted on 2020-08-04
4050 Functional Predictors of Causative Cis-Regulatory Mutations in Mendelian Disease
Bengani, H.; Grozeva, D.; Moyon, L.; Bhatia, S.; Louros, S. R.; Hope, J.; Jackson, A.; Prendergast, J.; Owen, L. J.; Naville, M.; Rainger, J.; Grimes, G.; Halachev, M.; Murphy, L. C.; Boskovic, O. S.; Heyningen, V. v.; Kind, P.; Abbott, C. M.; Osterweil, E.; Raymond, L.; Roest Crollius, H.; FitzPatrick, D.
10.1101/2020.08.03.232926 — genetics — Posted on 2020-08-03
4053 Automated generation of context-specific Gene Regulatory Networks with a weighted approach in D. melanogaster
Murgas, L.; Contreras-Riquelme, S.; Martinez, J. E.; Villaman, C.; Santibanez, R.; Martin, A. J.
10.1101/2020.08.03.232959 — bioinformatics — Posted on 2020-08-04
4054 Dense, high-resolution mapping of cells and tissues from pathology images for the interpretable prediction of molecular phenotypes in cancer
Diao, J. A.; Chui, W. F.; Wang, J. K.; Mitchell, R. N.; Rao, S. K.; Resnick, M. B.; Lahiri, A.; Maheshwari, C.; Glass, B.; Mountain, V.; Kerner, J. K.; Montalto, M. C.; Khosla, A.; Wapinski, I. N.; Beck, A. H.; Taylor-Weiner, A.; Elliott, H.
10.1101/2020.08.02.233197 — bioinformatics — Posted on 2020-08-04
4056 Acidic monosaccharides become incorporated into calcite single crystals
Lang, A.; Mijowska, S.; Polishchuk, I.; Falini, G.; Fermani, S.; Katsman, A.; Marin, F.; Pokroy, B.
10.1101/2020.08.03.234310 — bioengineering — Posted on 2020-08-04
4058 Optimal seasonal routines across animals and latitudes
Thygesen, U. H.; Visser, A. W.; Heilmann, I.; Andersen, K. H.
10.1101/2020.08.02.213595 — ecology — Posted on 2020-08-03
4059 Twisting of the heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process
Tessadori, F.; Kruse, F.; van den Brink, S. C.; van den Boogaard, M.; Christoffels, V. M.; Bakkers, J.
10.1101/2020.08.03.230359 — developmental biology — Posted on 2020-08-03
4060 Maternal iron deficiency perturbs embryonic cardiovascular development
Kalisch-Smith, J. I.; Ved, N.; Szumska, D.; Munro, J.; Troup, M.; Harris, S. E.; Jacquemot, A.; Miller, J. J.; Stuart, E. M.; Wolna, M.; Hardman, E.; Prin, F.; Lana-Elola, E.; Aoidi, R.; Fisher, E. M. C.; Tybulewicz, V. L. J.; Mohun, T. J.; Lakhal-Littleton, S.; Giannoulatou, E.; Sparrow, D. B.
10.1101/2020.08.03.230615 — developmental biology — Posted on 2020-08-03
4064 EpiGraphDB: a database and data mining platform for health data science
Liu, Y.; Elsworth, B. L.; Erola, P.; Haberland, V.; Hemani, G.; Lyon, M. S.; Zheng, J.; Gaunt, T. R.
10.1101/2020.08.01.230193 — bioinformatics — Posted on 2020-08-04
4065 Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells
Tristan, C. A.; Ormanoglu, P.; Slamecka, J.; Malley, C.; Chu, P.-H.; Jovanovic, V. M.; Gedik, Y.; Bonney, C.; Barnaeva, E.; Braisted, J.; Mallanna, S. K.; Dorjsuren, D.; Iannotti, M. J.; Voss, T. C.; Michael, S.; Simeonov, A.; Singec, I.
10.1101/2020.08.03.235242 — bioengineering — Posted on 2020-08-04
4067 scGNN: a novel graph neural network framework for single-cell RNA-Seq analyses
Wang, J.; Ma, A.; Chang, Y.; Gong, J.; Jiang, Y.; Fu, H.; Wang, C.; Qi, R.; Ma, Q.; Xu, D.
10.1101/2020.08.02.233569 — bioinformatics — Posted on 2020-08-03
4070 Integrated intra- and intercellular signaling knowledge for multicelullar omics analysis
Turei, D.; Valdeolivas, A.; Gul, L.; Palacio-Escat, N.; Ivanova, O.; Gabor, A.; Modos, D.; Korcsmaros, T.; Saez-Rodriguez, J.
10.1101/2020.08.03.221242 — systems biology — Posted on 2020-08-03
4072 Time-course transcriptome landscape of achene development in lettuce
Luo, C.; Wang, S.; Ning, K.; Chen, Z.; Yang, J.; Wang, Y.; Qi, M.; Wang, Q.
10.1101/2020.08.03.233387 — plant biology — Posted on 2020-08-03
4074 A miR-137-related biological pathway of risk for Schizophrenia is associated with human brain emotion processing
Pergola, G.; Rampino, A.; Di Carlo, P.; Marakhovskaia, A.; Quarto, T.; Fazio, L.; Papalino, M.; Torretta, S.; Amoroso, N.; Nair, M.; Domenici, E.; Dukart, J.; Khlghatyan, J.; Monaco, A.; Popolizio, T.; Romano, R.; Sportelli, L.; Blasi, G.; Zunuer, H.; Beaulieu, M.; Bertolino, A.
10.1101/2020.08.03.230227 — neuroscience — Posted on 2020-08-03
4075 Sex identification in embryos and adults of Darwins finches
Dobreva, M. P.; Lynton-Jenkins, J. G.; Chaves, J. A.; Tokita, M.; Bonneaud, C.; Abzhanov, A.
10.1101/2020.08.03.233924 — molecular biology — Posted on 2020-08-03
4077 Genome-wide association study of TP53 R249S mutation in hepatocellular carcinoma with aflatoxin B1 exposure and hepatitis B virus infection in Guangxi
Han, C.; Yu, T.; Qin, W.; Liao, X.; Huang, J.; Liu, Z.; Yu, L.; Liu, X.; Chen, Z.; Yang, C.; Wang, X.; Mo, S.; Zhu, G.; Su, H.; Mo, Z.; Peng, T.
10.1101/2020.08.03.235135 — genetics — Posted on 2020-08-03
4080 Assembly defects of the human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia
Sekulovski, S.; Devant, P.; Panizza, S.; Gogakos, T.; Pitiriciu, A.; Heitmeier, K.; Ramsay, E. P.; Barth, M.; Schmidt, C.; Weitzer, S.; Tuschl, T.; Baas, F.; Martinez, J.; Trowitzsch, S.
10.1101/2020.08.03.234229 — biochemistry — Posted on 2020-08-03
4083 An MRI protocol for anatomical and functional evaluation of the California sea lion brain
Cook, P.; Hoard, V.; Dolui, S.; Frederick, B.; Redfern, R.; Dennison, S.; Halaska, B.; Bloom, J.; Kruse-Elliott, K.; Whitmer, E.; Trumbull, E.; Berns, G.; Detre, J.; D'Esposito, M.; Gulland, F.; Reichmuth, C.; Johnson, S.; Field, C.; Inglis, B.
10.1101/2020.08.02.233429 — neuroscience — Posted on 2020-08-03
4084 Esrrb is a cell cycle dependent priming factor balancing between pluripotency and differentiation
Herchcovici Levi, S.; Arnon, L.; Feldman, S.; Alajem, A.; Bavli, D.; Sun, X.; Buganim, Y.; Ram, O.
10.1101/2020.08.03.234112 — genomics — Posted on 2020-08-03
4090 Src activates retrograde membrane traffic through phosphorylation of GBF1
Chia, J.; Wang, S.; Wee, S.; Gill, D. J.; Lee, V.; Kannan, S.; Verma, C.; Gunaratne, J.; Bard, F.
10.1101/2020.08.02.233353 — cell biology — Posted on 2020-08-03
4094 Marine reserve benefits and recreational fishing yields: the winners and the losers
Kayal, M.; Cigala, M.; Cambra, E.; Soulat, N.; Mercader, M.; Lebras, A.; Ivanoff, P.; Sebesi, L.; Lassus-Debat, A.; Hartmann, V.; Bradtke, M.; Lenfant, P.; Jabouin, C.; Dubreuil, J.; Pelletier, D.; Joguet, M.; Le Mellionnec, S.; Brichet, M.; Binche, J.-L.; Payrot, J.; Saragoni, G.; Crechriou, R.; Verdoit-Jarraya, M.
10.1101/2020.08.03.233981 — ecology — Posted on 2020-08-03
4095 Reconciling fish and farms: Methods for managing California rice fields as salmon habitat
Holmes, E. J.; Saffarinia, P.; Rypel, A. L.; Bell-Tilcock, M. N.; Katz, J. V.; Jeffres, C. A.
10.1101/2020.08.03.234054 — ecology — Posted on 2020-08-03
4098 A genetic probe for visualizing glutamatergic synapses and vesicles by 3D electron microscopy
Steinkellner, T.; Madany, M.; Haberl, M. G.; Zell, V.; Li, C.; Hu, J.; Mackey, M.; Ramachandra, R.; Adams, S.; Ellisman, M. H.; Hnasko, T.; BOASSA, D.
10.1101/2020.07.31.230995 — neuroscience — Posted on 2020-08-03
4099 Reaching for known unknowns: Rapid reach decisions accurately reflect the future state of dynamic probabilistic information
Wispinski, N. J.; Stone, S. A.; Bertrand, J. K.; Ouellette Zuk, A. A.; Lavoie, E. B.; Gallivan, J. P.; Chapman, C. S.
10.1101/2020.07.31.231563 — neuroscience — Posted on 2020-08-03
4102 Mutational Survivorship Bias: The case of PNKP
Bermudez-Guzman, L.; Jimenez-Huezo, G.; Arguedas, A.; Leal, A.
10.1101/2020.08.03.233957 — molecular biology — Posted on 2020-08-03
4104 Reconciling fish and farms: Methods for managing California rice fields as salmon habitat
Holmes, E. J.; Saffarinia, P.; Rypel, A. L.; Bell-Tilcock, M. N.; Katz, J. V.; Jeffres, C. A.
10.1101/2020.08.03.234062 — ecology — Posted on 2020-08-03
4106 Neural effects of placebo analgesia in fibromyalgia patients and healthy individuals
Frangos, E.; Ceko, M.; Wang, B.; Richards, E. A.; Gracely, J. L.; Colloca, L.; Schweinhardt, P.; Bushnell, M. C.
10.1101/2020.07.31.231191 — neuroscience — Posted on 2020-08-03
4107 Retinal optic flow during natural locomotion
Matthis, J. S.; Muller, K. S.; Bonnen, K. L.; Hayhoe, M. M.
10.1101/2020.07.23.217893 — neuroscience — Posted on 2020-08-03
4108 A Bayesian analysis of the association between Leukotriene A4 Hydrolase genotype and survival probability of tuberculous meningitis patients treated with adjunctive dexamethasone
Whitworth, L.; Coxon, J.; van Laarhoven, A.; Thuong, N. T. T.; Dian, S.; Alisjahbana, B.; Ganiem, A. R.; van Crevel, R.; Thwaites, G.; Troll, M.; Edelstein, P.; Sewell, R.; Ramakrishnan, L.
10.1101/2020.08.03.233791 — molecular biology — Posted on 2020-08-03
4110 Human vulnerability to cancer malignancy is enhanced by evolution of higher mesenchymal CD44 expression compared to other mammals
Ma, X.; Dighe, A.; Maziarz, J.; Neumann, E.; Erkenbrack, E.; Hei, Y.-Y.; Liu, Y.; Suhail, Y.; Kshitiz, K.; Levchenko, A.; Wagner, G.
10.1101/2020.08.03.234617 — evolutionary biology — Posted on 2020-08-03
4117 Light environment influences mating behaviours during the early stages of divergence in tropical butterflies
Hausmann, A. E.; Kuo, C.-Y.; Freire, M.; Rueda-M, N.; Linares, M.; Pardo-Diaz, C.; Salazar, C.; Merrill, R. M.
10.1101/2020.07.28.224915 — evolutionary biology — Posted on 2020-08-03
4120 De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
Baker, D.; Cao, L.; Goreshnik, I.; Coventry, B.; Case, J. B.; Miller, L.; Kozodoy, L.; Chen, R. E.; Carter, L.; Walls, A.; Park, Y.-J.; Stewart, L.; Diamond, M.; Veesler, D.
10.1101/2020.08.03.234914 — synthetic biology — Posted on 2020-08-03
4122 CSPα reduces aggregates and rescues striatal dopamine release in αsynuclein transgenic mice
Calo, L.; Hidari, E.; Wegrzynowicz, M.; Dalley, J.; Schneider, B.; Anichtchik, O.; Carlson, E.; Klenerman, D.; Spillantini, M. G.
10.1101/2020.07.31.229153 — neuroscience — Posted on 2020-08-03
4123 Integrated tapered fibertrode for simultaneous control and readout of neural activity over small brain volumes with reduced light-induced artefacts
Spagnolo, B.; Peixoto, R.; Sileo, L.; Pisanello, M.; Pisano, F.; Assad, J. A.; Sabatini, B. L.; DeVittorio, m.; Pisanello, F.
10.1101/2020.07.31.226795 — neuroscience — Posted on 2020-08-03
4127 Sex differences in nociceptor translatomes contribute to divergent prostaglandin signaling in male and female mice
Tavares-Ferreira, D.; Ray, P.; Sankaranarayanan, I.; Mejia, G. L.; Wangzhou, A.; Shiers, S.; Uttarkar, R. S.; Megat, S.; Barragan-Iglesias, P.; Dussor, G.; Akopian, A. N.; Price, T. J.
10.1101/2020.07.31.231753 — neuroscience — Posted on 2020-08-03
4128 Aspergillus fumigatus G-protein coupled receptors GprM and GprJ are important for the regulation of the cell wall integrity pathway, secondary metabolite production, and virulence
da Costa Filho, A. P.; Brancini, G. T.; de Castro, P. A.; Ferreira, J. A.; Silva, L. P.; Rocha, M. C.; Malavazi, I.; de Moraes Pontes, J. G.; Fill, T.; Silva, R.; Almeida, F.; Steenwyk, J. L.; Rokas, A.; dos Reis, T. F.; Ries, L. N.; Goldman, G. H.
10.1101/2020.08.03.235119 — microbiology — Posted on 2020-08-03
4130 The effect of wild Saccharomyces on composition and aroma of the Sauvignon blanc
Camargo Mendes, S. D.; Arcari, S. G.; Castrillon, M. R.; Werner, S. S.; Valente, P.
10.1101/2020.08.03.214437 — microbiology — Posted on 2020-08-03
4135 PAN-INDIA 1000 SARS-CoV-2 RNA Genome Sequencing Reveals Important Insights into the Outbreak
Maitra, A.; Raghav, S.; Dalal, A.; Ali, F.; Paynter, V. M.; Paul, D.; Biswas, N. K.; Ghosh, A.; Jani, K.; Chinnaswamy, S.; Pati, S.; Sahu, A.; Mitra, D.; Bhat, M. K.; Mayor, S.; Sarin, A.; The PAN-INDIA 1000 SARS-CoV-2 RNA Genome Sequencing Consortium, ; Shouche, Y. S.; Seshasayee, A. S. N.; Palakodeti, D.; Bashyam, M. D.; PARIDA, A.; Das, S.
10.1101/2020.08.03.233718 — genomics — Posted on 2020-08-03
4137 Genomics of a killifish from the Seychelles islands supports transoceanic island colonization and reveals relaxed selection of developmental genes
Cui, R.; Tyers, A. M.; Malubhoy, Z. J.; Wisotsky, S.; Valdesalici, S.; Henriette, E.; Kosakovsky Pond, S. L.; Valenzano, D. R.
10.1101/2020.08.03.232421 — evolutionary biology — Posted on 2020-08-03
4139 Structure-Based Design of a Cyclic Peptide Inhibitor of the SARS-CoV-2 Main Protease
Kreutzer, A. G.; Krumberger, M.; Parrocha, C. M. T.; Morris, M. A.; Guaglianone, G.; Nowick, J. S.
10.1101/2020.08.03.234872 — biochemistry — Posted on 2020-08-03
4145 Variation in VKORC1 is associated with vascular dementia
Mur, J.; McCartney, D. L.; Chasman, D. I.; Visscher, P. M.; Muniz-Terrera, G.; Cox, S. R.; Russ, T. C.; Marioni, R. E.
10.1101/2020.07.31.231126 — genetics — Posted on 2020-08-03
4146 Multi-organ signaling mobilizes tumor-associated erythroid cells expressing immune checkpoint molecules
Sano, Y.; Yoshida, T.; Choo, M.-K.; Jimenez-Andrade, Y.; Hill, K. R.; Georgopoulos, K.; Park, J. M.
10.1101/2020.07.31.231001 — cancer biology — Posted on 2020-08-03
4148 De novo design of ACE2 protein decoys to neutralize SARS-CoV-2
Linsky, T. W.; Vergara, R.; Codina, N.; Nelson, J. W.; Walker, M. J.; Su, W.; Hsiang, T.-Y.; Esser-Nobis, K.; Yu, K.; Hou, Y. J.; Priya, T.; Mitsumoto, M.; Pong, A.; Lau, U. Y.; Mason, M. L.; Chen, J.; Chen, A.; Berrocal, T.; Peng, H.; Clairmont, N. S.; Castellanos, J.; Lin, Y.-R.; Josephson-Day, A.; Baric, R. S.; Walkey, C. D.; Swanson, R.; Blancas-Mejia, L. M.; Gale, M.; Yen, H.-L.; Silva, D.-A.
10.1101/2020.08.03.231340 — biochemistry — Posted on 2020-08-03
4150 The genetic architecture of host response reveals the importance of arbuscular mycorrhizae to maize cultivation
Ramirez Flores, M. d. R.; Perez-Limon, S.; Li, M.; Barrales-Gamez, B.; Olalde-Portugal, V.; Sawers, R. J. H.
10.1101/2020.07.06.190223 — plant biology — Posted on 2020-08-03
4151 Motor cortical dynamics are shaped by multiple distinct subspaces during naturalistic behavior
Perich, M. G.; Conti, S.; Badi, M.; Bogaard, A.; Barra, B.; Wurth, S.; Bloch, J.; Courtine, G.; Micera, S.; Capogrosso, M.; Milekovic, T.
10.1101/2020.07.30.228767 — neuroscience — Posted on 2020-08-03
4152 Motor planning modulates neural activity patterns in early human auditory cortex
Gale, D. J.; Areshenkoff, C. N.; Honda, C. T.; Johnsrude, I. S.; Flanagan, J. R.; Gallivan, J. P.
10.1101/682609 — neuroscience — Posted on 2020-08-03
4153 Peptide YY: a novel Paneth cell antimicrobial peptide that maintains fungal commensalism
Pierre, J. F.; La Torre, D.; Sidebottom, A.; Kambal, A.; Zhu, X.; Tao, Y.; Cham, C. M.; Wang, L.; Harris, K. G.; Zaborina, O.; Alverdy, J. C.; Herzog, H.; Witchley, J.; Noble, S. M.; Leone, V.; Chang, E. B.
10.1101/2020.05.15.096875 — molecular biology — Posted on 2020-08-03
4156 Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity
Liu, H.; Wu, N. C.; Yuan, M.; Bangaru, S.; Torres, J. L.; Caniels, T. G.; van Schooten, J.; Zhu, X.; Lee, C.-C. D.; Brouwer, P. J. M.; van Gils, M. J.; Sanders, R. W.; Ward, A. B.; Wilson, I. A.
10.1101/2020.08.02.233536 — microbiology — Posted on 2020-08-03
4158 SARS-CoV-2 ORF6 disrupts nucleocytoplasmic transport through interactions with Rae1 and Nup98
Addetia, A.; Lieberman, N. A. P.; Phung, Q.; Xie, H.; Roychoudhury, P.; Loprieno, M. A.; Huang, M.; Shrestha, L.; Jerome, K. R.; Greninger, A. L.
10.1101/2020.08.03.234559 — microbiology — Posted on 2020-08-03
4159 Functional immune mapping with deep-learning enabled phenomics applied to immunomodulatory and COVID-19 drug discovery
Cuccarese, M. F.; Earnshaw, B. A.; Heiser, K.; Fogelson, B.; Davis, C. T.; McLean, P. F.; Gordon, H. B.; Skelly, K.-R.; Weathersby, F. L.; Rodic, V.; Quigley, I. K.; Pastuzyn, E. D.; Mendivil, B. M.; Lazar, N. H.; Brooks, C. A.; Carpenter, J.; Jacobson, P.; Glazier, S. W.; Ford, J.; Jensen, J. D.; Campbell, N. D.; Statnick, M. A.; Low, A. S.; Thomas, K. R.; Carpenter, A. E.; Hegde, S. S.; Alfa, R. W.; Victors, M. L.; Haque, I. S.; Chong, Y. T.; Gibson, C. C.
10.1101/2020.08.02.233064 — immunology — Posted on 2020-08-03
4160 Treatment with commonly used antiretroviral drugs induces a type I/III interferon signature in the gut in the absence of HIV infection
Hughes, S. M.; Levy, C. N.; Calienes, F.; Stekler, J. D.; Pandey, U.; Vojtech, L.; Berard, A. R.; Birse, K.; Noel-Romas, L.; Richardson, B.; Golden, J. B.; Cartwright, M.; Collier, A. C.; Stevens, C. E.; Curlin, M. E.; Holtz, T. H.; Mugo, N.; Irungu, E.; Katabira, E.; Muwonge, T.; Lama, J. R.; Baeten, J. M.; Burgener, A.; Lingappa, J. R.; McElrath, M. J.; Mackelprang, R.; McGowan, I.; Cranston, R. D.; Cameron, M. J.; Hladik, F.
10.1101/701961 — immunology — Posted on 2020-08-03
4161 A genomic dating tool for ancient genomes resolves the origins of hundreds of Eurasian genomes
Esposito, U.; Holland, G.; Alshehab, G.; Dobre, A. M.; Pirooznia, M.; Brimacombe, C.; Elhaik, E.
10.1101/828962 — genomics — Posted on 2020-08-03
4162 The Na+/K+ ATPase Regulates Glycolysis and Modifies Immune metabolism in Tumors
Sanderson, S. M.; Xiao, Z.; Wisdom, A. J.; Bose, S.; Liberti, M. V.; Reid, M. A.; Hocke, E.; Gregory, S. G.; Kirsch, D. G.; Locasale, J. W.
10.1101/2020.03.31.018739 — cancer biology — Posted on 2020-08-03
4163 Measuring reading ability in the web-browser with a lexical decision task
Yeatman, J. D.; Tang, K. A.; Donnelly, P. M.; Yablonski, M.; Ramamurthy, M.; Karipidis, I. I.; Caffarrra, S.; Takada, M. E.; Ben-Shachar, M.; Domingue, B. W.
10.1101/2020.07.30.229658 — animal behavior and cognition — Posted on 2020-08-03
4164 SARS-CoV-2 genome sequences from late April in Stockholm, Sweden reveal a novel mutation in the spike protein
Soratto, T. A. T.; Darban, H.; Bjerkner, A.; Coorens, M.; Albert, J.; Allander, T.; Andersson, B.
10.1101/2020.08.03.233866 — bioinformatics — Posted on 2020-08-03
4165 How to map a plantain: phylogeny of the diverse Plantagineae (Lamiales)
Shipunov, A.; Fernandez, J. L.; Hassemer, G.; Alp, S.; Lee, H. J.; Pay, K.
10.1101/2020.07.31.230813 — plant biology — Posted on 2020-08-03
4166 All hands on deck: Large-scale (re)sculpting of cortical circuits in post-resection children
Maallo, A. M. S.; Granovetter, M. C.; Freud, E.; Kastner, S.; Pinsk, M. A.; Patterson, C.; Behrmann, M.
10.1101/2020.07.01.183400 — neuroscience — Posted on 2020-08-03
4169 Age-related expression of SARS-CoV-2 priming protease TMPRSS2 in the developing lung
Schuler, B. A.; Habermann, A. C.; Plosa, E. J.; Taylor, C. J.; Jetter, C. S.; Kapp, M. E.; Benjamin, J.; Gulleman, P.; Nichols, D. S.; Braunstein, L. Z.; Koval, M. H.; Guttentag, S. H.; Blackwell, T. S.; Vanderbilt COVID-19 Consortium Cohort, ; Webber, S. A.; Banovich, N.; Kropski, J. A.; Sucre, J. M.; HCA Lung Biological Network,
10.1101/2020.05.22.111187 — developmental biology — Posted on 2020-08-03
4171 ChipSeg: an automatic tool to segment bacteria and mammalian cells cultured in microfluidic devices
de Cesare, I.; Zamora-Chimal, C. G.; Postiglione, L.; Khazim, M. R.; Pedone, E.; Shannon, B.; Fiore, G.; Perrino, G.; Napolitano, S.; di Bernardo, D.; Savery, N.; Grierson, C.; di Bernardo, M.; Marucci, L.
10.1101/2020.08.03.225045 — synthetic biology — Posted on 2020-08-03
4172 SARS-CoV-2-specific T cells exhibit unique features reflecting robust helper function, lack of terminal differentiation, and high proliferative potential
Neidleman, J.; Luo, X.; Frouard, J.; Xie, G.; Gill, G.; Stein, E. S.; McGregor, M.; Ma, T.; George, A.; Kosters, A.; Greene, W. C.; Vasquez, J.; Ghosn, E.; Lee, S.; Roan, N. R.
10.1101/2020.06.08.138826 — immunology — Posted on 2020-08-03
4174 Shifts from pulled to pushed range expansions caused by reduction of landscape connectedness
Dahirel, M.; Bertin, A.; Haond, M.; Blin, A.; Lombaert, E.; Calcagno, V.; Fellous, S.; Mailleret, L.; Malausa, T.; Vercken, E.
10.1101/2020.05.13.092775 — ecology — Posted on 2020-08-03
4175 Gene-level heritability analysis explains the polygenic architecture of cancer
Fanfani, V.; Citi, L.; Harris, A. L.; Pezzella, F.; Stracquadanio, G.
10.1101/599753 — cancer biology — Posted on 2020-08-03
4176 CryoFold: Ab-initio structure determination from electron density maps using molecular dynamics
Shekhar, M.; Terashi, G.; Gupta, C.; Sarkar, D.; Debussche, G.; Sisco, N.; Nguyen, J.; Mondal, A.; Zook, J.; Vant, J.; Fromme, P.; van Horn, W. D.; Kihara, D.; Tajkhorshid, E.; Dill, K.; Perez, A.; Singharoy, A.
10.1101/687087 — biophysics — Posted on 2020-08-03
4178 CRISPR interference as low burden logic inverters in synthetic circuits: characterization and tuning
Bellato, M.; Frusteri Chiacchiera, A.; Salibi, E.; Casanova, M.; De Marchi, D.; Cusella De Angelis, M. G.; Pasotti, L.; Magni, P.
10.1101/2020.08.03.234096 — synthetic biology — Posted on 2020-08-03
4179 REGN-COV2 antibody cocktail prevents and treats SARS-CoV-2 infection in rhesus macaques and hamsters
Baum, A.; Copin, R.; Ajithdoss, D.; Zhou, A.; Lanza, K.; Negron, N.; Ni, M.; Wei, Y.; Atwal, G. S.; Oyejide, A.; Goez-Gazi, Y.; Dutton, J.; Clemmons, E.; Staples, H. M.; Bartley, C.; Klaffke, B.; Alfson, K.; Gazi, M.; Gonzales, O.; Dick, E.; Carrion, R.; Pessaint, L.; Porto, M.; Cook, A.; Brown, R.; Ali, V.; Greenhouse, J.; Taylor, T.; Andersen, H.; Lewis, M. G.; Stahl, N.; Murphy, A. J.; Yancopoulos, G. D.; Kyratsous, C. A.
10.1101/2020.08.02.233320 — microbiology — Posted on 2020-08-03
4180 Natural Killer cell activation, reduced ACE2, TMPRSS2, cytokines G-CSF, M-CSF and SARS-CoV-2-S pseudovirus infectivity by MEK inhibitor treatment of human cells
Zhou, L.; Huntington, K.; Zhang, S.; Carlsen, L.; So, E.-Y.; Parker, C.; Sahin, I.; Safran, H.; Kamle, S.; Lee, C.-M.; Lee, C.-G.; Elias, J. A.; Campbell, K. S.; Naik, M. T.; Atwood, W. J.; Youssef, E.; Pachter, J. A.; Navaraj, A.; Seyhan, A. A.; Liang, O.; El-Deiry, W.
10.1101/2020.08.02.230839 — cell biology — Posted on 2020-08-03
4181 Mechanism of duplex unwinding by coronavirus nsp13 helicases
Hu, X.; Hao, W.; Qin, B.; Tian, Z.; Li, Z.; Hou, P.; Zhao, R.; Cui, S.; Diao, J.
10.1101/2020.08.02.233510 — biophysics — Posted on 2020-08-03
4185 High-Spatial-Resolution Multi-Omics Atlas Sequencing of Mouse Embryos via Deterministic Barcoding in Tissue
Liu, Y.; Yang, M.; Deng, Y.; Su, G.; Archibald Enninful, A.; Guo, C. C.; Tebaldi, T.; Zhang, D.; Kim, D.; Bai, Z.; Norris, E.; Pan, A.; Li, J.; Xiao, Y.; Halene, S.; Fan, R.
10.1101/2020.08.01.232496 — genomics — Posted on 2020-08-03
4188 SLO2.1 and NALCN form a functional complex to modulate myometrial cell excitability
Ferreira, J. J.; Amazu, C.; Puga-Molina, L. C.; England, S. K.; Santi, C. M.
10.1101/2020.07.31.229138 — cell biology — Posted on 2020-08-03
4189 Cardiac Cell-Derived Matrices Impart Age-Specific Functional Properties to Human Cardiomyocytes
Kauss, M. A.; Rockwood, S. J.; Silva, A. C.; Joy, D. A.; Mendoza-Camacho, N.; Whittaker, M. N.; Stevenson, E.; Krogan, N. J.; Swaney, D. L.; McDevitt, T. C.
10.1101/2020.07.31.231480 — cell biology — Posted on 2020-08-03
4194 Characterisation of Medicago truncatula CLE34 and CLE35 in nodulation control
Mens, C.; Hastwell, A. H.; Su, H.; Gresshoff, P. M.; Mathesius, U.; Ferguson, B. J.
10.1101/2020.07.31.231605 — plant biology — Posted on 2020-08-03
4196 The Effect of Introgression of an R2R3 MYB Transcription Factor on Sulphur Metabolism in Brassica oleracea
Neequaye, M.; Saha, S.; Steuernagel, B.; Troncoso-Rey, P.; van den Bosch, F.; Stephenson, P.; Traka, M. H.; Ostergaard, L.; Mithen, R.
10.1101/2020.08.02.232819 — plant biology — Posted on 2020-08-03
4200 Spatially Restricted Immune Responses Allow for Root Meristematic Activity During Bacterial Colonisation
Emonet, A.; Zhou, F.; Vacheron, J.; Heiman, C. M.; Denervaud Tendon, V.; Ma, K.-W.; Schulze-Lefert, P.; Keel, C.; Geldner, N.
10.1101/2020.08.03.233817 — plant biology — Posted on 2020-08-03
4202 Variation in VKORC1 is associated with vascular dementia
McCartney, D. L.; Chasman, D. I.; Visscher, P. M.; Muniz-Terrera, G.; Cox, S. R.; Russ, T. C.; Marioni, R. E.; Mur, J.
10.1101/2020.07.31.231126 — genetics — Posted on 2020-08-03
4203 Model-based genotype and ancestry estimation for potential hybrids with mixed-ploidy
Shastry, V.; Adams, P. E.; Lindtke, D.; Mandeville, E. G.; Parchman, T. L.; Gompert, Z.; Buerkle, C. A.
10.1101/2020.07.31.231514 — genetics — Posted on 2020-08-03
4204 Morphological and genomic shifts in mole-rat 'queens' increase fecundity but reduce skeletal integrity
Johnston, R. A.; Vullioud, P.; Thorley, J.; Kirveslahti, H.; Shen, L.; Mukherjee, S.; Karner, C.; Clutton-Brock, T.; Tung, J.
10.1101/2020.07.31.231266 — evolutionary biology — Posted on 2020-08-03
4207 The mammalian CLU homolog FMT controls development and behavior in Arabidopsis
Horvath, T.; Ralevski, A.; Apelt, F.; Olas, J.; Mueller-Roeber, B.; Rugarli, E.; Kragler, F.
10.1101/2020.08.01.231183 — plant biology — Posted on 2020-08-03
4211 Zooplankton community beta diversity in an Amazonian floodplain lake
Gomes, L. F.; Gomes, A. C. A. M.; de Souza, C. A.; Pereira, H. R.; Bonnet, M.-P.; Vieira, L. C. G.
10.1101/2020.07.31.231241 — ecology — Posted on 2020-08-03
4214 Uncovering Transcriptional Dark Matter via Gene Annotation Independent Single-Cell RNA Sequencing Analysis
Wang, M. F. Z.; Mantri, M.; Chou, S.-P.; Scuderi, G. J.; McKellar, D.; Butcher, J. T.; Danko, C. G.; De Vlaminck, I.
10.1101/2020.07.31.229575 — bioinformatics — Posted on 2020-08-03
4220 High-Spatial-Resolution Multi-Omics Atlas Sequencing of Mouse Embryos via Deterministic Barcoding in Tissue
Liu, Y.; Yang, M.; Deng, Y.; Su, G.; Enninful, A.; Guo, C. C.; Tebaldi, T.; Zhang, D.; Kim, D.; Bai, Z.; Norris, E.; Pan, A.; Li, J.; Xiao, Y.; Halene, S.; Fan, R.
10.1101/788992 — genomics — Posted on 2020-08-03
4223 Multi-organ signaling mobilizes tumor-associated erythroid cells expressing immune checkpoint molecules
Sano, Y.; Yoshida, T.; Choo, M.-K.; Jimenez-Andrade, Y.; Hill, K. R.; Georgopoulos, K.; Park, J. M.
10.1101/2020.07.31.231001 — cancer biology — Posted on 2020-08-03
4224 HDAC1 regulates the chromatin landscape to establish transcriptional dependencies in chronic lymphocytic leukemia
Lai, T.-h.; Ozer, H. G.; Gasparini, P.; Giovanni, N.; Destafano, R.; Ravikrishnan, J.; Tsai, T.-l.; Lapalombella, R.; Woyach, J.; Puduvalli, V.; Blachly, J.; Byrd, J. C.; Sampath, D.
10.1101/2020.08.03.232561 — cancer biology — Posted on 2020-08-03
4227 Hematopoietic stem cells fail to regenerate following inflammatory challenge.
Bogeska, R.; Kaschutnig, P.; Fawaz, M.; Mikecin, A.-M.; Buechler-Schaeff, M.; Paffenholz, S.; Asada, N.; Frauhammer, F.; Buettner, F.; Ball, M.; Knoch, J.; Staeble, S.; Walter, D.; Petri, A.; Carreno-Gonzalez, M. J.; Wagner, V.; Brors, B.; Haas, S.; Lipka, D. B.; Essers, M. A. G.; Holland-Letz, T.; Mallm, J.-P.; Rippe, K.; Frenette, P. S.; Rieger, M. A.; Milsom, M. D.
10.1101/2020.08.01.230433 — cell biology — Posted on 2020-08-03
4228 Efficient population modification gene-drive rescue system in the malaria mosquito Anopheles stephensi
Adolfi, A.; Gantz, V. M.; Jasinskiene, N.; Lee, H.-F.; Hwang, K.; Bulger, E. A.; Ramaiah, A.; Bennett, J. B.; Terradas, G.; Emerson, J. J.; Marshall, J. M.; Bier, E.; James, A. A.
10.1101/2020.08.02.233056 — genetics — Posted on 2020-08-03
4232 The DCC receptor regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation
Morcom, L.; Gobius, I.; Marsh, A. P. L.; Suarez, R.; Bridges, C.; Ye, Y.; Fenlon, L.; Zagar, Y.; Douglas, A. M.; Donahoo, A.-L.; Fothergill, T.; Shaikh, S.; Kozulin, P.; Edwards, T. J.; Cooper, H. M.; admin@irc5.org, ; Sherr, E. H.; Chedotal, A.; Leventer, R.; Lockhart, P.; Richards, L. J.
10.1101/2020.08.03.233593 — neuroscience — Posted on 2020-08-03
4233 Sweet anticipation: Predictability of familiar music in autism
Da Mota, P. A.; Stark, E. A.; Fernandes, H. M.; Ahrends, C.; Cabral, J.; Gebauer, L.; Happe, F.; Vuust, P.; Kringelbach, M. L.
10.1101/2020.08.03.233668 — neuroscience — Posted on 2020-08-03
4234 Behavioural and transcriptomic characterization of the comorbidity between Alzheimer s disease and Major Depression
Martin-Sanchez, A.; Pinero, J.; Nonell, L.; Arnal, M.; Ribe, E. M.; Nevado Holgado, A.; Lovestone, S.; Sanz, F.; Furlong, L. I.; Valverde, O.
10.1101/2020.07.31.231159 — neuroscience — Posted on 2020-08-03
4237 Inferring Adaptive Introgression Using Hidden Markov Models
Svedberg, J.; Shchur, V.; Reinman, S.; Nielsen, R.; Corbett-Detig, R.
10.1101/2020.08.02.232934 — evolutionary biology — Posted on 2020-08-02
4240 A sensory integration account for time perception
Toso, A.; Fassihi, A.; Paz, L.; Pulecchi, F.; Diamond, M. E.
10.1101/2020.08.02.232801 — neuroscience — Posted on 2020-08-02
4241 The vesicular release probability sets the strength of individual Schaffer collateral synapses
Duerst, C.; Wiegert, J. S.; Schulze, C.; Helassa, N.; Török, K.; Oertner, T. G.
10.1101/2020.08.02.232850 — neuroscience — Posted on 2020-08-02
4244 NPC1-mTORC1 signaling Couples Cholesterol Sensing to Organelle Homeostasis and is a Targetable Pathway in Niemann-Pick type C
Davis, O. B.; Shin, H. R.; Lim, C.-Y.; Wu, E. Y.; Kukurugya, M.; Maher, C. F.; Perera, R. M.; Ordonez, P.; Zoncu, R.
10.1101/2020.08.02.233254 — cell biology — Posted on 2020-08-02
4250 Pheromone receptor of the globally invasive quarantine pest of the palm tree, the red palm weevil (Rhynchophorus ferrugineus)
Antony, B.; Johny, J.; Montagne, N.; Jacquin-Joly, E.; Capoduro, R.; Cali, K.; Persaud, K.; Al-Saleh, M. A.; Pain, A.
10.1101/2020.07.31.230326 — neuroscience — Posted on 2020-08-02
4252 The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration
Rigo, F.; Jafar-nejad, P.; Powers, B.; Soriano, A.; Zhao, H.; Norris, D. A.; Matson, J.; DeBrosse-Serra, B.; Watson, J.; Narayanan, P.; Mazur, C.; Kordasiewicz, H.; Swayze, E. E.; Narayanan, P.
10.1101/2020.07.31.216721 — neuroscience — Posted on 2020-08-02
4253 Subgenomic satellite particle generation in recombinant AAV vectors results from DNA lesion/breakage and non-homologous end joining
Zhang, J.; Guo, P.; Yu, X.; Pouchnik, D.; Firrman, J.; Wei, H.; Sang, N.; Li, D.; Herzog, R.; Diao, Y.; Xiao, W.
10.1101/2020.08.01.230755 — molecular biology — Posted on 2020-08-02
4254 Microbiome-derived metabolites reproduce the mitochondrial dysfunction and decreased insulin sensitivity observed in type 2 diabetes
Ormsby, M. J.; Hulme, H.; Villar, V. H.; Hamm, G.; Rodriguez-Blanco, G.; Bragg, R. A.; Strittmatter, N.; Schofield, C. J.; Delles, C.; Salt, I. P.; Tardito, S.; Burchmore, R.; Goodwin, R. J. A.; Wall, D. M.
10.1101/2020.08.02.232447 — microbiology — Posted on 2020-08-02
4255 p53 Controls Murine Gammaherpesvirus Latency and Prevents Infection-Associated IgH/c- Myc Translocations
Owens, S. M.; Sifford, J. M.; Li, G.; Ghosh, D.; Miller, A. D.; Stumhofer, J.; Forrest, J. C.
10.1101/2020.08.02.233148 — microbiology — Posted on 2020-08-02
4257 Efficient population modification gene-drive rescue system in the malaria mosquito Anopheles stephensi
Adolfi, A.; Gantz, V. M.; Jasinskiene, N.; Lee, H.-F.; Hwang, K.; Bulger, E. A.; Ramaiah, A.; Bennett, J. B.; Terradas, G.; Emerson, J. J.; Marshall, J. M.; Bier, E.; James, A. A.
10.1101/2020.08.02.233056 — genetics — Posted on 2020-08-02
4259 Exacerbation of mitochondrial fission in human CD34+ cells halts erythropoiesis and hemoglobin biosynthesis
Gonzalez, A. M.; Ruiz, L. M.; Jensen, E. L.; Echeverria, C. A.; Romero, V.; Stiles, L.; Shirihai, O. S.; Elorza, A. A.
10.1101/2020.07.31.230961 — cell biology — Posted on 2020-08-02
4263 Molecular Parallelism Underlies Convergent Highland Adaptation of Maize Landraces
Wang, L.; Josephs, E.; Lee, K.; Roberts, L.; Rellan-Alvarez, R.; Ross-Ibarra, J.; Hufford, M. B.
10.1101/2020.07.31.227629 — evolutionary biology — Posted on 2020-08-02
4264 Gut microbiota alterations due to fecal transplant
Olekhnovich, E. I.; Ivanov, A. B.; Ulyantsev, V. I.; Ilina, E. N.
10.1101/2020.07.31.231233 — bioinformatics — Posted on 2020-08-02
4267 Injectable Myocardial Matrix Hydrogel Mitigates Negative Left Ventricular Remodeling in a Chronic Myocardial Infarction Model
Diaz, M. D.; Tran, E.; Wassenaar, J.; Spang, M.; Gaetani, R.; Luo, C.; Braden, R.; Hill, R. C.; Hansen, K. C.; DeMaria, A. N.; Christman, K.
10.1101/2020.07.31.231449 — bioengineering — Posted on 2020-08-02
4273 A Systemic and Molecular Study of Subcellular Localization of SARS-CoV-2 Proteins
Zhang, J.; Cruz-cosme, R.; Zhuang, M.-W.; Liu, D.; Liu, Y.; Teng, S.; Wang, P.-H.; Tang, Q.
10.1101/2020.08.02.233023 — microbiology — Posted on 2020-08-02
4275 Supersized ribosomal RNA expansion segments in Asgard archaea
Penev, P. I.; Fakhretaha-Aval, S.; Patel, V. J.; Cannone, J. J.; Gutell, R. R.; Petrov, A. S.; Williams, L. D.; Glass, J. B.
10.1101/2019.12.25.888164 — evolutionary biology — Posted on 2020-08-02
4276 Reduction of Elevated Proton Leak Rejuvenates Mitochondria in the Aged Cardiomyocyte
Zhang, H.; Alder, N. N.; Wang, W.; Szeto, H.; Marcinek, D. J.; Rabinovitch, P. S.
10.1101/2020.01.02.893362 — cell biology — Posted on 2020-08-02
4277 Functional succinate dehydrogenase deficiency and loss of ascorbic acid transporter SLC23A1 are pathognomonic adverse features of clear cell renal cancer
Aggarwal, R. K.; Zou, Y.; Luchtel, R. A.; Pradhan, K.; Ashai, N.; Ramachandra, N.; Albanese, J.; Yang, J.-i.; Wang, X.; Aluri, S.; Gordon, S.; Machha, V.; Tischer, A.; Aboumohamed, A.; Gartrell, B. A.; Hafizi, S.; Pullman, J.; Shenoy, N.
10.1101/2020.07.05.188433 — cancer biology — Posted on 2020-08-02
4278 Common variants associated with OSMR expression contribute to carotid plaque vulnerability, but not to cardiovascular disease in humans
van Keulen, D.; van Koeverden, I. D.; Boltjes, A.; Princen, H. M. G.; van Gool, A. J.; de Borst, G. J.; Asselbergs, F. W.; Tempel, D.; Pasterkamp, G.; van der Laan, S. W.
10.1101/576793 — genetics — Posted on 2020-08-02
4279 Purification of recombinant SARS-CoV-2 spike, its receptor binding domain, and CR3022 mAb for serological assay
Tee, K. L.; Jackson, P. J.; Scarrott, J. M.; Jaffe, S. R.; Johnson, A. O.; Johari, Y.; Pohle, T. H.; Mozzanino, T.; Price, J.; Grinham, J.; Brown, A.; Nicklin, M. J.; James, D. C.; Dickman, M. J.; Wong, T. S.
10.1101/2020.07.31.231282 — biochemistry — Posted on 2020-08-02
4281 The distribution of plasmid fitness effects explains plasmid persistence in bacterial communities
Alonso-del Valle, A.; Leon-Sampedro, R.; Rodriguez-Beltran, J.; DelaFuente, J.; Hernandez-Garcia, M.; Ruiz-Garbajosa, P.; Canton, R.; Pena-Miller, R.; San Millan, A.
10.1101/2020.08.01.230672 — microbiology — Posted on 2020-08-02
4283 Predator: A novel method for targeted protein degradation
Liu, C.; Kuang, J.; Qiu, X.; Min, L.; Li, W.; Ma, J.; Zhu, L.
10.1101/2020.07.31.231787 — synthetic biology — Posted on 2020-08-02
4284 Myocardial matrix material supports a proliferative microenvironment for cardiomyocytes
Wang, R. M.; Cattaneo, P.; Luo, C.; Camboa, N.; Braden, R.; Christman, K.; Evans, S.
10.1101/2020.07.31.231845 — bioengineering — Posted on 2020-08-02
4285 Bone marrow adipogenic lineage precursors (MALPs) promote osteoclastogenesis in bone remodeling and pathologic bone loss
Yu, W.; Zhong, L.; Yao, L.; Wei, Y.; Gui, T.; Li, Z.; Kim, H.; Dyment, N.; Liu, X. S.; Yang, S.; Choi, Y.; Ahn, J.; Qin, L.
10.1101/2020.08.01.231829 — cell biology — Posted on 2020-08-02
4289 NAD modulates DNA methylation and cell differentiation
Ummarino, S.; Bassal, M. A.; Zhang, Y.; Seelam, A. J.; Kobayashi, I. S.; Borchiellini, M.; Ebralidze, A. K.; Trinh, B. Q.; Kobayashi, S. S.; Di Ruscio, A.
10.1101/2020.07.31.231555 — molecular biology — Posted on 2020-08-02
4295 Adaptive laboratory evolution restores solvent tolerance in plasmid-cured Pseudomonas putida S12; a molecular analysis
Kusumawardhani, H.; Furtwaengler, B.; Blommestijn, M.; Kaltenyte, A.; van der Poel, J.; Kolk, J.; Hosseini, R.; de Winde, J. H.
10.1101/2020.08.01.232264 — microbiology — Posted on 2020-08-01
4296 High-Spatial-Resolution Multi-Omics Atlas Sequencing of Mouse Embryos via Deterministic Barcoding in Tissue
Liu, Y.; Yang, M.; Deng, Y.; Su, G.; Archibald Enninful, A.; Guo, C. C.; Tebaldi, T.; Zhang, D.; Kim, D.; Bai, Z.; Norris, E.; Pan, A.; Li, J.; Xiao, Y.; Halene, S.; Fan, R.
10.1101/2020.08.01.232496 — genomics — Posted on 2020-08-01
4301 Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy
Barone, S. M.; Paul, A. G. A.; Muehling, L. M.; Lannigan, J. A.; Kwok, W. W.; Turner, R. B.; Woodfolk, J. A.; Irish, J. M.
10.1101/2020.07.31.190454 — systems biology — Posted on 2020-08-01
4304 Engineered ACE2 receptor traps potently neutralize SARS-CoV-2
Glasgow, A.; Glasgow, J. E.; Limonta, D.; Solomon, P.; Lui, I.; Zhang, Y.; Nix, M. A.; Rettko, N. J.; Lim, S. A.; Zha, S.; Yamin, R.; Kao, K.; Rosenberg, O. S.; Ravetch, J. V.; Wiita, A. P.; Leung, K. K.; Zhou, X. X.; Hobman, T. C.; Kortemme, T. K.; Wells, J. A.
10.1101/2020.07.31.231746 — bioengineering — Posted on 2020-08-01
4307 MacaquePose: A novel 'in the wild' macaque monkey pose dataset for markerless motion capture
Labuguen, R.; Matsumoto, J.; Negrete, S.; Nishimaru, H.; Nishijo, H.; Takada, M.; Go, Y.; Inoue, K.-i.; Shibata, T.
10.1101/2020.07.30.229989 — neuroscience — Posted on 2020-08-01
4308 Identification of H3N2 NA and PB1-F2 genetic variants and their association with disease symptoms in the 2014-15 influenza season
Blumenkrantz, D.; Mehoke, T.; Hardick, J.; Shaw-Saliba, K.; Powell, H.; Wohlgemuth, N.; Liu, H.; Macias, E.; Evans, J.; Lewis, M.; Medina, R.; Sauer, L. M.; Dugas, A.; DuVal, A.; Lane, A. P.; Gaydos, C.; Rothman, R.; Thielen, P.; Pekosz, A.
10.1101/2020.02.20.956979 — microbiology — Posted on 2020-08-01
4313 A peptide of a type I toxin-antitoxin system induces Helicobacter pylori morphological transformation from spiral-shape to coccoids
El Mortaji, L.; Tejada-Arranz, A.; Rifflet, A.; Boneca, I. G.; Pehau-Arnaudet, G.; Radicella, P.; Marsin, S.; De Reuse, H.
10.1101/585380 — microbiology — Posted on 2020-08-01
4314 Heritability and family-based GWAS analyses of the N-acyl ethanolamine and ceramide plasma lipidome
McGurk, K. A.; Williams, S. G.; Guo, H.; Watkins, H.; Farrall, M.; Cordell, H. J.; Nicolaou, A.; Keavney, B. D.
10.1101/815654 — genetics — Posted on 2020-08-01
4315 Quantifying the effect of experimental perturbations in single-cell RNA-sequencing data using graph signal processing
Burkhardt, D. B.; Stanley, J. S.; Perdigoto, A. L.; Gigante, S. A.; Herold, K. C.; Wolf, G.; Giraldez, A. J.; van Dijk, D.; Krishnaswamy, S.
10.1101/532846 — bioinformatics — Posted on 2020-08-01
4316 Engineered ACE2 receptor traps potently neutralize SARS-CoV-2
Glasgow, A.; Glasgow, J. E.; Limonta, D.; Solomon, P.; Lui, I.; Zhang, Y.; Nix, M. A.; Rettko, N. J.; Lim, S. A.; Zha, S.; Yamin, R.; Kao, K.; Rosenberg, O. S.; Ravetch, J. V.; Wiita, A. P.; Leung, K. K.; Zhou, X. X.; Hobman, T. C.; Kortemme, T. K.; Wells, J. A.
10.1101/2020.07.31.231746 — bioengineering — Posted on 2020-08-01
4317 Toward a Monte Carlo Approach to Selecting Climate Variables in MaxEnt: A Case Study Using Cassin's Sparrow (Peucaea cassinii)
Schnase, J. L.; Carroll, M. L.; Gill, R. L.; Tamkin, G. S.; Li, J.; Strong, S. L.; Maxwell, T. P.; Aronne, M. E.
10.1101/2020.07.15.202945 — ecology — Posted on 2020-08-01
4318 The SSVEP tool as a marker of subjective visibility
de Heering, A.; Beauny, A.; Vuillaume, L.; Salvesen, L.; Cleeremans, A.
10.1101/588236 — neuroscience — Posted on 2020-08-01
4320 Multiplexed fractionated proteomics reveals synaptic factors associated with cognitive resilience in Alzheimer's Disease
Carlyle, B. C.; Kandigian, S. E.; Kreuzer, J.; Das, S.; Trombetta, B. A.; Kuo, Y.; Bennett, D. A.; Schneider, J. A.; Petyuk, V. A.; Kitchen, R. R.; Morris, R.; Nairn, A. C.; Hyman, B. T.; Haas, W.; Arnold, S. E.
10.1101/2020.07.31.230680 — neuroscience — Posted on 2020-08-01