bioRxiv directory

2 Characterisation of factors contributing to the performance of nonwoven fibrous matrices as substrates for adenovirus vectored vaccine stabilisation

Dulal, P.; Walters, A. A.; Hawkins, N.; Claridge, T. D.; Kowal, K.; Neill, S.; Russell, S. J.; Ritchie, A. J.; Ashfield, R.; Hill, A. V.; Douglas, A. D.

10.1101/2020.01.31.928218 — pharmacology and toxicology — Posted on 2020-01-31

3 Nucleotide Analogues as Inhibitors of Viral Polymerases

Ju, J.; Kumar, S.; Li, X.; Jockusch, S.; Russo, J. J.

10.1101/2020.01.30.927574 — pharmacology and toxicology — Posted on 2020-01-31

4 Crocus Sativus and Its Active Compound, Crocin Inhibits the Endothelial Activation and Monocyte-Endothelial Cells Interaction in Stimulated Human Coronary Artery Endothelial Cells

Mohd Kasim, N. A.; Abu Bakar, N. A.; Ahmad, R.; Abd Rahim, I. N.; Abdul Rahman, T. H.; Froemming, G. R. A.; Mohd Nawawi, H.

10.1101/2020.01.31.928341 — pathology — Posted on 2020-01-31

5 Less physical activity and more varied and disrupted sleep is associated with a less favorable metabolic profile in adolescents

Rögnvaldsdottir, V.; Brychta, R. J.; Hrafnkelsdottir, S. M.; Cheng, K. Y.; Arngrimsson, S. A.; Johannsson, E.; Gudmundsdottir, S. L.

10.1101/2020.01.31.928333 — pathology — Posted on 2020-01-31

6 Online analysis of microendoscopic 1-photon calcium imaging data streams

Friedrich, J.; Giovannucci, A.; Pnevmatikakis, E. A.

10.1101/2020.01.31.929141 — neuroscience — Posted on 2020-01-31

7 An iron (II) dependent oxygenase performs the last missing step of plant lysine catabolism

Thompson, M. G.; Blake-Hedges, J. M.; Pereira, J. H.; Hangasky, J. A.; Belcher, M. S.; Moore, W. M.; Barajas, J. F.; Cruz-Morales, P.; Washington, L. J.; Haushalter, R. W.; Eiben, C. B.; Liu, Y.; Skyrud, W.; Benites, V. T.; Barnum, T. P.; Baidoo, E. E.; Scheller, H.; Marletta, M. A.; Shih, P. M.; Adams, P. D.; Keasling, J. D.

10.1101/2020.01.30.927905 — molecular biology — Posted on 2020-01-31

8 Sero-prevalence of brucellosis, Q-fever and Rift Valley Fever in humans and livestock in Somali region, Ethiopia

Ibrahim, M.; Schelling, E.; Zinsstag, J.; Hattendorf, J.; Andargie, E.; Tschopp, R.

10.1101/2020.01.31.928374 — microbiology — Posted on 2020-01-31

9 Haplotype Diversity and Sequence Heterogeneity of Human Telomeres

Grigorev, K.; Foox, J.; Bezdan, D.; Butler, D.; Luxton, J. J.; Reed, J.; Meydan, C.; Bailey, S.; Mason, C.

10.1101/2020.01.31.929307 — genomics — Posted on 2020-01-31

10 Characterization and Mitigation of Fragmentation Enzyme-Induced Dual Stranded Artifacts

Gregory, C. T.; Ngankeu, A.; Orwick, S.; Kautto, E.; Woyach, J. A.; Byrd, J. C.; Blachly, J. S.

10.1101/2020.01.30.927491 — bioinformatics — Posted on 2020-01-31

11 Utilization of a cell-penetrating peptide-adaptor for delivery of HPV protein E2 into cervical cancer cells to arrest cell growth and promote cell death

McMurry, J. L.; LeCher, J. C.; Didier, H. L.; Dickson, R. L.; Slaughter, L. R.; Bejarano, J. C.; Ho, S.; Nowak, S. J.; Chrestensen, C. A.

10.1101/2020.01.31.928358 — cell biology — Posted on 2020-01-31

12 Trade-off between virulence and dispersal drives parasite evolution at experimental invasion front

Noergaard, L. S.; Zilio, G.; Saade, C.; Gougat-Barbera, C.; Hall, M. D.; Fronhofer, E. A.; Kaltz, O.

10.1101/2020.01.31.928150 — evolutionary biology — Posted on 2020-01-31

13 Toward a unified dilution effect theory: How competence, competition, and the transmission mechanism influence disease-diversity relationships

Cortez, M.; Duffy, M. A.

10.1101/2020.01.31.928820 — ecology — Posted on 2020-01-31

14 Biotic and abiotic drivers of soil microbial functions across tree diversity experiments

Cesarz, S.; Craven, D.; Auge, H.; Bruelheide, H.; Castagneyrol, B.; Hector, A.; Jactel, H.; Koricheva, J.; Messier, C.; Muys, B.; O'Brien, M. J.; Paquette, A.; Potvin, C.; Reich, P. B.; Scherer-Lorenzen, M.; Smith, A. R.; Verheyen, K.; Eisenhauer, N.

10.1101/2020.01.30.927277 — ecology — Posted on 2020-01-31

15 A High Throughput Gravimetric Phenotyping Platform for Real Time Physiological Screening of Plant Environment Dynamic Responses

Dalal, A.; Shenhar, I.; Bourstein, R.; Mayo, A.; Grunwald, Y.; Averbuch, N.; Attia, Z.; Wallach, R.; Moshelion, M.

10.1101/2020.01.30.927517 — plant biology — Posted on 2020-01-31

16 TOR coordinates nucleotide availability with ribosome biogenesis in plants

Brunkard, J. O.; Busche, M.; Scarpin, M. R.; Hnasko, R.

10.1101/2020.01.30.927418 — plant biology — Posted on 2020-01-31

17 Targeting Reactive Aldehyde Detoxification by Aldehyde Dehydrogenase 2 (ALDH2) as a Treatment Strategy for Endometriosis

McAllister, S.; Sinharoy, P.; Vasu, M.

10.1101/2020.01.30.927376 — physiology — Posted on 2020-01-31

18 Clinically applicable histopathological diagnosis system for gastric cancer detection using deep learning

Song, Z.; Zou, S.; Zhou, W.; Huang, Y.; Shao, L.; Yuan, J.; Gou, X.; Jin, W.; Wang, Z.; Chen, X.; Ding, X.; Liu, J.; Yu, C.; Ku, C.; Liu, C.; Sun, Z.; Xu, G.; Wang, Y.; Zhang, X.; Wang, D.; Wang, S.; Xu, W.; Davis, R. C.; Shi, H.

10.1101/2020.01.30.927749 — pathology — Posted on 2020-01-31

19 Influences of age and pubertal status on number of perineuronal nets in the rat medial prefrontal cortex

Drzewiecki, C. M.; Willing, J.; Juraska, J. M.

10.1101/2020.01.31.929257 — neuroscience — Posted on 2020-01-31

20 Pial surface CSF-contacting texture, subpial and funicular plexus in the thoracic spinal cord in monkey: NADPH diaphorase histological configuration

Li, Y.; Hou, W.; Jia, Y.; Wen, X.; Rao, C.; Xu, X.; Wei, Z.; Bai, L.; Tan, H.

10.1101/2020.01.30.927509 — neuroscience — Posted on 2020-01-31

21 Effects of dopamine agonist treatment on resting-state network connectivity in Parkinson's disease

Cole, D. M.; Mohammadi, B.; Milenkova, M.; Kollewe, K.; Schrader, C.; Samii, A.; Dengler, R.; Muente, T. F.; Beckmann, C. F.

10.1101/2020.01.31.928853 — neuroscience — Posted on 2020-01-31

22 A Disinhibitory Circuit for Contextual Modulation in Primary Visual Cortex

Keller, A. J.; Roth, M. M.; Caudill, M.; Dipoppa, M.; Miller, K. D.; Scanziani, M.

10.1101/2020.01.31.929166 — neuroscience — Posted on 2020-01-31

23 Single cell transcriptome profiling of the Atlantic cod immune system

Guslund, N. C.; Solbakken, M. H.; Jentoft, S.; Jakobsen, K. S.; Qiao, S.-W.

10.1101/2020.01.31.926410 — immunology — Posted on 2020-01-31

24 Species boundaries and molecular markers for classification among 16SrI phytoplasmas informed by genome analysis

Cho, S.-T.; Kung, H.-J.; Huang, W.; Hogenhout, S. A.; Kuo, C.-H.

10.1101/2020.01.31.928135 — genomics — Posted on 2020-01-31

25 Slope-Hunter: A robust method for index-event bias correction in genome-wide association studies of subsequent traits

Mahmoud, O.; Dudbridge, F.; Smith, G. D.; Munafo, M.; Tilling, K.

10.1101/2020.01.31.928077 — genetics — Posted on 2020-01-31

26 Human iPSC modeling reveals mutation-specific responses to gene therapy in Best disease

Sinha, D.; Steyer, B. G.; Shahi, P. K.; Mueller, K.; Valiauga, R.; Edwards, K. L.; Bacig, C.; Steltzer, S. S.; Srinivasan, S.; Abdeen, A.; Cory, E.; Periyasamy, V.; Siahpirani, A. F.; Stone, E. M.; Tucker, B. A.; Roy, S.; Pattnaik, B. R.; Saha, K.; Gamm, D. M.

10.1101/796581 — genetics — Posted on 2020-01-31

27 Further perceptions of probability: in defence of trial-by-trial updating models

Forsgren, M.; Juslin, P.; van den Berg, R.

10.1101/2020.01.30.927558 — animal behavior and cognition — Posted on 2020-01-31

28 An adaptable analysis workflow for characterization of platelet spreading and morphology

Pike, J. A.; Simms, V. A.; Smith, C. W.; Morgan, N. V.; Khan, A. O.; Poulter, N. S.; Styles, I. B.; Thomas, S. G.

10.1101/2020.01.31.928168 — bioinformatics — Posted on 2020-01-31

29 Primary Human Hepatocytes Maintain Long-term Functions in Porous Silk Scaffolds Containing Extracellular Matrix Proteins

Kukla, D.; Stoppel, W.; Kaplan, D.; Khetani, S.

10.1101/2020.01.30.927814 — bioengineering — Posted on 2020-01-31

30 GAMIBHEAR: whole-genome haplotype reconstruction from Genome Architecture Mapping data

Markowski, J.; Kempfer, R.; Kukalev, A.; Irastorza-Azcarate, I.; Loof, G.; Pombo, A.; Schwarz, R. F.

10.1101/2020.01.30.927061 — bioinformatics — Posted on 2020-01-31

31 Tomato wall-associated kinase SlWak1 acts in an Fls2- and Fls3-dependent manner to promote apoplastic immune responses to Pseudomonas syringae

Zhang, N.; Pombo, M. A.; Rosli, H. G.; Martin, G. B.

10.1101/2020.01.27.921460 — plant biology — Posted on 2020-01-31

32 BELIEFS AND ATTITUDES TOWARDS CHILD EPILEPSY: A STRUCTURAL EQUATION MODEL

Silva, L. G.; Beltrao, I. S.; Bandeira, P. F. R.; Delmondes, G. A.; Alencar, C. D.; Damasceno, S. S.; Kerntopf, M. R.

10.1101/2020.01.30.927681 — neuroscience — Posted on 2020-01-31

33 Skill-specific changes in cortical preparatory activity during motor learning

Sun, X.; O'Shea, D. J.; Golub, M. D.; Trautmann, E. M.; Vyas, S.; Ryu, S. I.; Shenoy, K. V.

10.1101/2020.01.30.919894 — neuroscience — Posted on 2020-01-31

34 The cellular basis of protease activated receptor type 2 (PAR2) evoked mechanical and affective pain

Hassler, S. N.; Kume, M.; Mwirigi, J. M.; Ahmad, A.; Shiers, S.; Wangzhou, A.; Ray, P.; Naik, D. K.; Burton, M. D.; Vagner, J.; Boitano, S.; Akopian, A. N.; Dussor, G.; Price, T. J.

10.1101/2020.01.31.928663 — neuroscience — Posted on 2020-01-31

35 Depletion of erythropoietic miR-486-5p and miR-451a improves detectability of rare microRNAs in peripheral blood-derived small RNA sequencing libraries

Juzenas, S.; Lindqvist, C. M.; Ito, G.; Dolshanskaya, Y.; Halfvarson, J.; Franke, A.; Hemmrich-Stanisak, G.

10.1101/789891 — molecular biology — Posted on 2020-01-31

36 Defective influenza A virus RNA products mediate MAVS-dependent upregulation of human leukocyte antigen class I proteins

Rahim, M. M. A.; Parsons, B.; Price, E. L.; Slaine, P. D.; Chilvers, B. L.; Seaton, G. S.; Wight, A.; Dey, S.; Grandy, S. L.; Anderson, L. E.; Zamorano Cuervo, N.; Grandvaux, N.; Gaglia, M. M.; Kelvin, A. A.; Khaperskyy, D. A.; McCormick, C.; Makrigiannis, A. P.

10.1101/2020.01.30.928051 — microbiology — Posted on 2020-01-31

37 Characterization of an ECF56-family sigma factor from Streptomyces venezuelae reveals a highly conserved regulome

Thompson, M. G.; Zargar, A.; Cruz-Morales, P.; De Rond, T.; Chang, S.; Pearson, A. N.; Goyal, G.; Barajas, J. F.; Blake-Hedges, J. M.; Phelan, R. M.; Reyes-Umana, V.; Hernandez, A. C.; Hillson, N. J.; Shih, P. M.; Keasling, J. D.

10.1101/2020.01.30.927608 — microbiology — Posted on 2020-01-31

38 Mechanistic Modeling of Biochemical Systems Without A Priori Parameter Values Using the Design Space Toolbox v.3.0

Valderrama-Gomez, M. A.; Lomnitz, J. G.; Fasani, R. A.; Savageau, M. A.

10.1101/2020.01.30.927657 — systems biology — Posted on 2020-01-31

39 aiMeRA: A generic modular response analysis R package and its application to estrogen and retinoic acid receptors crosstalk

Jimenez-Dominguez, G.; Ravel, P.; Jalaguier, S.; Cavailles, V.; Colinge, J.

10.1101/2020.01.30.925800 — systems biology — Posted on 2020-01-31

40 The bacterial quorum sensing signal DSF hijacks Arabidopsis thaliana sterol biosynthesis to suppress plant innate immunity

Tran, T. M.; Ma, Z.; Triebl, A.; Nath, S.; Cheng, Y.; Gong, B.-Q.; Han, X.; Wang, J.; Li, J.-F.; Wenk, M. R.; Torta, F.; Mayor, S.; Yang, L.; MIAO, Y.

10.1101/2020.01.30.927731 — plant biology — Posted on 2020-01-31

41 Retinotopic remapping in the visual system of deaf adults

Levine, A. T.; Yuen, K.; Billawa, S.; Bridge, L.; Clausen, S.; Cole, E. J.; Wang, V.; Canavan, S.; Spencer, L.; Campbell, C.; Morland, A. B.; Codina, C.; Buckley, D.; Baseler, H. A.

10.1101/2020.01.31.923342 — neuroscience — Posted on 2020-01-31

42 Cortical morphology at birth reflects spatio-temporal patterns of gene expression in the fetal brain

Ball, G.; Seidlitz, J.; O'Muircheartaigh, J.; Dimitrova, R.; Fenchel, D.; Makropoulos, A.; Christiaens, D.; Schuh, A.; Passerat-Palmbach, J.; Hutter, J.; Cordero-Grande, L.; Hughes, E.; Price, A.; Hajnal, J. V.; Rueckert, D.; Robinson, E. C.; Edwards, D.

10.1101/2020.01.28.922849 — neuroscience — Posted on 2020-01-31

43 JNK signaling controls branching, nucleokinesis, and positioning of centrosomes and primary cilia in migrating cortical interneurons

Smith, S. E.; Coker, N. K.; Tucker, E.

10.1101/2020.01.30.927855 — neuroscience — Posted on 2020-01-31

44 Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies

Demura, K.; Kusakizako, T.; Shihoya, W.; Hiraizumi, M.; Nomura, K.; Shimada, H.; Yamashita, K.; Nishizawa, T.; Taruno, A.; Nureki, O.

10.1101/2020.01.31.928093 — molecular biology — Posted on 2020-01-31

45 Prebiotics and community composition influence gas production of the human gut microbiota

Yu, X.; Gurry, T.; Nguyen, L. T. T.; Richardson, H. S.; Alm, E.

10.1101/2020.01.30.928085 — microbiology — Posted on 2020-01-31

46 Functional signatures of evolutionarily young CTCF binding sites

Azazi, D.; Mudge, J. M.; Odom, D. T.; Flicek, P.

10.1101/2020.01.31.928119 — genomics — Posted on 2020-01-31

47 Genetic Analyses of Blood Cell Structure for Biological and Pharmacological Inference

Akbari, P.; Vuckovic, D.; Jiang, T.; Kundu, K.; Kreuzhuber, R.; Bao, E. L.; Mayer, L.; Collins, J. H.; Downes, K.; Georges, M.; Grassi, L.; Guerrero, J. A.; Kaptoge, S.; Knight, J. C.; Meacham, S.; Sambrook, J.; Seyres, D.; Stegle, O.; Verboon, J. M.; Walter, K.; Watkins, N. A.; Danesh, J.; Roberts, D. J.; Di Angelantonio, E.; Sankaran, V. G.; Frontini, M.; Burgess, S.; Kuijpers, T.; Peters, J. E.; Butterworth, A. S.; Ouwehand, W. H.; Soranzo, N.; Astle, W. J.

10.1101/2020.01.30.927483 — genetics — Posted on 2020-01-31

48 A preliminary ecological profile of Kyasanur Forest disease virus hosts among the mammalian wildlife of the Western Ghats, India

Walsh, M.; Mor, S.; Maity, H.; Hossain, S.

10.1101/2020.01.30.927939 — ecology — Posted on 2020-01-31

49 Autophagy promotes cell and organismal survival by maintaining NAD(H) pools

Sedlackova, L.; Otten, E. G.; Scialo, F.; Shapira, D.; Kataura, T.; Carroll, B.; Seranova, E.; Rabanal Ruiz, Y.; Kelly, G.; Stefanatos, R.; Nelson, G.; Acharjee, A.; Kenneth, N. S.; Trushin, S. A.; Bascom, C.; Tasseff, R.; Isfort, R. I.; Oblong, J.; Trushina, E.; Imoto, M.; Saiki, S.; Lazarou, M.; Papamichos Chronakis, M.; Maddocks, O. D. K.; Sarkar, S.; Sanz, A.; Korolchuk, V. I.

10.1101/2020.01.31.928424 — cell biology — Posted on 2020-01-31

50 Novel software for automated morphometric analysis of stented arteries

Resnick, A.; Hooshdaran, B.; Pressly, B. B.; Guerrero, D. T.; Alferiev, I. S.; Chorny, M.; Levy, R. J.; Fishbein, I.

10.1101/2020.01.30.927459 — bioinformatics — Posted on 2020-01-31

51 RESTORE: Robust intEnSiTy nORmalization mEthod for Multiplexed Imaging

Chang, Y. H.; Chin, K.; Thibault, G.; Eng, J.; Burlingame, E.; Gray, J. W.

10.1101/792770 — bioinformatics — Posted on 2020-01-31

52 Directed assembly and concentrating of micro/nanoparticles, cells, and vesicles via low-power near-infrared laser generated plasmonic microbubbles

Ohannesian, N.; Li, J.; Misbah, I.; Zhao, F.; Shih, W.-C.

10.1101/2020.01.30.927269 — bioengineering — Posted on 2020-01-31

53 An injectable meta-biomaterial

Beduer, A.; Bonini, F.; Bonini, F.; Burch, P.; Braschler, T.

10.1101/2020.01.30.926931 — bioengineering — Posted on 2020-01-31

54 Neurothreads: Cryogel carrier-based differentiation and delivery of mature neurons in the treatment of Parkinson's disease

Filippova, A.; Bonini, F.; Efremova, L.; Preynat-Seauve, O.; Beduer, A.; Krause, K.-H.; Braschler, T.

10.1101/2020.01.30.927244 — bioengineering — Posted on 2020-01-31

55 Highly efficient cardiac differentiation and maintenance by thrombin-coagulated fibrin hydrogels enriched with decellularized porcine heart extracellular matrix

Navaee, F.; Renaud, P.; Braschler, T.

10.1101/2020.01.30.927319 — bioengineering — Posted on 2020-01-31

56 Alteration of perivascular spaces in early cognitive decline

Sepehrband, F.; Barisano, G.; Sheikh-Bahaei, N.; Choupan, J.; Cabeen, R. P.; Crawford, M. S.; Mack, W. J.; Chui, H. C.; Ringman, J. M.; Toga, A. W.

10.1101/2020.01.30.927350 — neuroscience — Posted on 2020-01-31

57 Regional and hemispheric susceptibility of the temporal lobe to FTLD-TDP-43-C pathology

Borghesani, V.; Battistella, G.; Mandelli, M. L.; Welch, A.; Weis, E.; Younes, K.; Neuhaus, J.; Grinberg, L. T.; Seeley, W. W.; Spina, S.; Miller, B. L.; Miller, Z.; Gorno-Tempini, M. L.

10.1101/847582 — neuroscience — Posted on 2020-01-31

58 Prefrontal state fluctuations control access to consciousness

Dwarakanath, A.; Kapoor, V.; Werner, J.; Safavi, S.; Fedorov, L.; Logothetis, N. K.; Panagiotaropoulos, T. I.

10.1101/2020.01.29.924928 — neuroscience — Posted on 2020-01-31

59 Spontaneous Axonal ER Ca2+ Waves Mediate A Shift From Action Potential-Dependent to Independent Glutamate Release in the YAC128 HD-Model

Mackay, J. P.; Buren, C.; Smith-Dijak, A. I.; Koch, E. T.; Zhang, P.; Schmidt, M.; Fung, E.; Nassrallah, W. B.; Hayden, M. R.; Raymond, L. A.

10.1101/2020.01.31.929299 — neuroscience — Posted on 2020-01-31

60 Genetic and functional diversification of chemosensory pathway receptors in filarial nematode parasites

Wheeler, N. J.; Heimark, Z. W.; Airs, P. M.; Mann, A.; Bartholomay, L. C.; Zamanian, M.

10.1101/683060 — microbiology — Posted on 2020-01-31

61 Systems-level analysis of monocyte responses in inflammatory bowel disease identifies IL-10 and IL-1 cytokine networks that regulate IL-23

Aschenbrenner, D.; Quaranta, M.; Banerjee, S.; Ilott, N.; Jansen, J.; Steere, B. A.; Chen, Y.-H.; Ho, S.; Cox, K.; Oxford IBD Cohort Investigators, ; Arancibia-Carcamo, C. V.; Coles, M.; Gaffney, E.; Travis, S.; Denson, L. A.; Kugathasan, S.; Schmitz, J.; Powrie, F.; Sansom, S.; Uhlig, H. H.

10.1101/719492 — immunology — Posted on 2020-01-31

62 The first eukaryotic kinome tree illuminates the dynamic history of present-day kinases

van Wijk, L. M.; Snel, B.

10.1101/2020.01.27.920793 — evolutionary biology — Posted on 2020-01-31

63 Field and mesocosm test methods to assess the performance of biodegradable plastic under marine conditions

Lott, C.; Eich, A.; Unger, B.; Makarow, D.; Battagliarin, G.; Schlegel, K. A.; Lasut, M. T.; Weber, M.

10.1101/2020.01.31.928606 — ecology — Posted on 2020-01-31

64 Cooperation for copulation: a novel ecological mechanism underlying the evolution of coalition for sharing mating opportunities

Toyoda, A.; Maruhashi, T.; Malaivijitnond, S.; Koda, H.; Ihara, Y.

10.1101/2020.01.30.927772 — animal behavior and cognition — Posted on 2020-01-31

65 A possible coding for experience: ripple-like events and synaptic diversity

Ishikawa, J.; Tomokage, T.; Mitsushima, D.

10.1101/2019.12.30.891259 — animal behavior and cognition — Posted on 2020-01-31

66 Does rehearsal benefit visual memory? The role of semantic associations in the maintenance of intact and phase scrambled scenes.

Reichert Plaska, C.; Ng, K.; Ellmore, T. M.

10.1101/753350 — neuroscience — Posted on 2020-01-31

67 Optimising network modelling methods for fMRI

Pervaiz, U.; Vidaurre, D.; Woolrich, M. W.; Smith, S. M.

10.1101/741595 — neuroscience — Posted on 2020-01-31

68 Homeostatic Plasticity Commonly Fails at the Intersection of Autism-Gene Mutations and a Novel Class of Common Phenotypic Modifier

Genc, O.; An, J. Y.; Fetter, R. D.; Kulik, Y.; Zunino, G.; Sanders, S. J.; Davis, G. W.

10.1101/2020.01.31.927665 — neuroscience — Posted on 2020-01-31

69 Common default mode network dysfunction across psychopathologies: A neuroimaging meta-analysis of the n-back working memory paradigm

Farruggia, M. C.; Laird, A. R.; Mattfeld, A. T.

10.1101/2020.01.30.927210 — neuroscience — Posted on 2020-01-31

70 Gjd2b-mediated gap junctions promote glutamatergic synapse formation and dendritic elaboration in Purkinje neurons

Sitaraman, S.; Yadav, G.; Jabeen, S.; Agarwal, V.; Thirumalai, V.

10.1101/2020.01.31.928242 — neuroscience — Posted on 2020-01-31

71 A Fob1 independent role for the Smc5/6 complex in the rDNA that modulates lifespan.

Moradi Fard, S.; Mojumdar, A.; Chan, M.; Harkness, T. A. A.; Cobb, J. A.

10.1101/2020.01.24.917203 — molecular biology — Posted on 2020-01-31

72 Identifying spawning activity in aquatic species based on environmental DNA spikes

Tsuji, S.; Shibata, N.

10.1101/2020.01.28.924167 — molecular biology — Posted on 2020-01-31

73 From sectors to speckles: The impact of long range migration on gene surfing

Paulose, J.; Hallatschek, O.

10.1101/803189 — evolutionary biology — Posted on 2020-01-31

74 Dynamic evolution of great ape Y chromosomes

Cechova, M.; Vegesna, R.; Tomaszkiewicz, M.; Harris, R. S.; Chen, D.; Rangavittal, S.; Medvedev, P.; Makova, K.

10.1101/2020.01.21.913863 — evolutionary biology — Posted on 2020-01-31

75 Selfish mitochondria exploit nutrient status across different levels of selection

Gitschlag, B. L.; Tate, A. T.; Patel, M. R.

10.1101/2020.01.30.927202 — evolutionary biology — Posted on 2020-01-31

76 A unified model of species abundance, genetic diversity, and functional diversity revealsthe mechanisms structuring ecological communities

Overcast, I.; Ruffley, M.; Rosindell, J.; Harmon, L.; Borges, P. A. V.; Emerson, B. C.; Etienne, R.; Gillespie, R.; Krehenwinkel, H.; Mahler, D. L.; Massol, F.; Parent, C.; Patino, J.; Peter, B.; Week, B.; Wagner, C.; Hickerson, M. J.; Rominger, A.

10.1101/2020.01.30.927236 — evolutionary biology — Posted on 2020-01-31

77 AVP-induced counter-regulatory glucagon is diminished in type 1 diabetes

Kim, A.; Knudsen, J. G.; Madara, J. C.; Benrick, A.; Hill, T.; Abdul Kadir, L.; Kellard, J. A.; Mellander, L.; Miranda, C.; Lin, H.; James, T.; Suba, K.; Spigelman, A.; Wu, Y.; MacDonald, P.; Wernstedt Asterholm, I.; Magnussen, T.; Christensen, M.; Vilsboll, T.; Salem, V.; Knop, F. K.; Rorsman, P.; Lowell, B. B.; Briant, L.

10.1101/2020.01.30.927426 — cell biology — Posted on 2020-01-31

78 Native Hydrogen/Deuterium Exchange Mass Spectrometry of Structured DNA Oligonucleotides

Largy, E.; Gabelica, V.

10.1101/848598 — biophysics — Posted on 2020-01-31

79 Degradation of white birch shelterbelts by attack of white-spotted longicorn beetle in central Hokkaido, northern Japan.

Masaka, K.; Wakita, Y.; Iwasaki, K.; Hayamizu, M.

10.1101/2020.01.30.926188 — ecology — Posted on 2020-01-31

80 The proteasomal deubiquitinating enzyme PSMD14 regulates macroautophagy by controlling Golgi-to-ER retrograde transport

Bustamante, H.; Cereceda, K.; Gonzalez, A.; Valenzuela, G.; Cheuquemilla, Y.; Hernandez, S.; Arias, E.; Cerda-Troncoso, C.; Bandau, S.; Soza, A.; Kausel, G.; Kerr, B.; Mardones, G.; Cancino, J.; Hay, R.; Rojas, A.; Burgos, P.

10.1101/2020.01.29.925503 — cell biology — Posted on 2020-01-31

81 Evaluating Representations for Gene Ontology Terms

Duong, D.; Uppunda, A.; Gai, L.; Ju, C. J.-T.; Zhang, J.; Chen, M.; Eskin, E.; Li, J. J.; Chang, K.-W.

10.1101/765644 — bioinformatics — Posted on 2020-01-31

82 Genome-wide investigation of gene-cancer associations for the prediction of novel therapeutic targets in oncology

Bazaga, A.; Leggate, D.; Weisser, H.

10.1101/2020.01.30.927285 — bioinformatics — Posted on 2020-01-31

83 Effect of acute physical exercise on motor sequence memory

Marin Bosch, B.; Bringard, A.; Logrieco, M. G.; Imobersteg, N.; Lauer, E.; Thomas, A.; Ferretti, G.; Schwartz, S.; Igloi, K.

10.1101/2020.01.28.922930 — neuroscience — Posted on 2020-01-31

84 Preliminary Evidence of the role of estrogen and tamoxifen-induced regulation of complement proteins in rat hippocampus

Kumar, P.; Dhar, P.

10.1101/2020.01.30.927392 — neuroscience — Posted on 2020-01-31

85 Spatio-temporal alterations in functional connectivity and white matter microstructure resulting from glucose hypometabolism in a rat model of sporadic Alzheimer's disease

Tristao Pereira, C.; Diao, Y.; Poitry-Yamate, C.; Yin, T.; Da Silva, A. R.; Gruetter, R.; Jelescu, I. O.

10.1101/2020.01.30.926444 — neuroscience — Posted on 2020-01-31

86 Two dominant brain states reflect optimal and suboptimal attention

Yamashita, A.; Rothlein, D.; Kucyi, A.; Valera, E. M.; Esterman, M.

10.1101/2020.01.31.928523 — neuroscience — Posted on 2020-01-31

87 Glutamate and γ-aminobutyric acid differentially modulate glymphatic clearance of amyloid β through pulsation- and aquaporin-4 dependent mechanisms

Wu, C.; Feng, Y.-w.; Zhang, Q.; Liang, F.-y.; Lan, Y.; Pei, Z.; Xu, G.-q.

10.1101/2020.01.31.928481 — neuroscience — Posted on 2020-01-31

88 Diagnostic Cerebrospinal Fluid Biomarker Discovery and Validation in Patients with Central Nervous System Infections

Thanh, T. T.; Casals-Pascual, C.; Ny, N. T. H.; Ngoc, N. M.; Geskus, R.; Nhu, L. N. T.; Hong, N. T. T.; Duc, D. T.; Thu, D. D. A.; Uyen, P. N.; Ngoc, V. B.; Chau, L. T. M.; Quynh, V. X.; Hanh, N. H. H.; Thuong, N. T. T.; Diem, L. T.; Hanh, B. T. B.; Hang, V. T. T.; Oanh, P. K. N.; Fischer, R.; Phu, N. H.; Nghia, H. D. T.; Nguyen, C.; Hoa, N. T.; Kessler, B. M.; Thwaites, G.; Tan, L. V.

10.1101/2020.01.13.899625 — microbiology — Posted on 2020-01-31

89 Degrees of compositional equilibrium in tree communities vary along a gradient of temperature change rates over one decade: Application of an individual-based temporal beta diversity concept

Nakadai, R.

10.1101/2020.01.30.920660 — ecology — Posted on 2020-01-31

90 Developmental regulation of oocyte lipid uptake via 'patent' follicular epithelium in Drosophila melanogaster

Row, S.; Deng, W.-M.

10.1101/2019.12.31.891838 — developmental biology — Posted on 2020-01-31

91 Residue-Level Allostery Propagates Through the Effective Coarse-Grained Hessian

Lake, P. T.; Davidson, R. B.; Klem, H.; Hocky, G. M.; McCullagh, M.

10.1101/822882 — biophysics — Posted on 2020-01-31

92 Correlation guided Network Integration (CoNI) reveals novel genetic regulators of hepatic metabolism

Klaus, V. S.; Schriever, S. C.; Peter, A.; Monroy-Kuhn, J. M.; Irmler, M.; Tokarz, J.; Prehn, C.; Kastenmueller, G.; Beckers, J.; Adamski, J.; Koenigsrainer, A.; Mueller, T. D.; Heni, M.; Tschoep, M. H.; Pfluger, P. T.; Lutter, D.

10.1101/2020.01.29.924944 — bioinformatics — Posted on 2020-01-31

93 Zero-shot imputations across species are enabled through joint modeling of human and mouse epigenomics

Schreiber, J.; Hegde, D.; Noble, W. S.

10.1101/801183 — bioinformatics — Posted on 2020-01-31

94 Method for identification of heme-binding proteins and quantification of their interactions

Bozinovic, N.; Noe, R.; Kanyavuz, A.; Lecerf, M.; Dimitrov, J. D.

10.1101/2019.12.17.879395 — biochemistry — Posted on 2020-01-31

95 Oviposition in flight: the Sabethes albiprivus incredible egg throwing behavior

Vieira, G.; Bersot, M. I. L.; Pereira, G. R.; de Abreu, F. V. S.; Nascimento-Pereira, A. C.; Neves, M. S. A. S.; Rosa-Freitas, M. G.; Motta, M. d. A.; Lourenco-de-Oliveira, R.

10.1101/2020.01.31.927228 — zoology — Posted on 2020-01-31

96 Loss of slc39a14 causes simultaneous manganese deficiency and hypersensitivity in zebrafish

Tuschl, K.; White, R. J.; Valdivia, L. E.; Niklaus, S.; Bianco, I. H.; Sealy, I. M.; Neuhauss, S. C.; Houart, C.; Wilson, S. W.; Busch-Nentwich, E. M.

10.1101/2020.01.31.921130 — neuroscience — Posted on 2020-01-31

97 Rapid adaptation to elevated extracellular potassium in the pyloric circuit of the crab, Cancer borealis

He, L. S.; Rue, M. C. P.; Morozova, E. O.; Powell, D. J.; James, E. J.; Kar, M.; Marder, E.

10.1101/636910 — neuroscience — Posted on 2020-01-31

98 Deficiency of Norepinephrine Transmission In Brain Contributed To Seizure-Induced Respiratory Arrest In the DBA/1 Mouse SUDEP Model

Shen, Y.; MA, H.; Lu, H.; Zhao, H.; Sun, J.; Cheng, Y.; Shen, Y.; Zhou, Y. D.; Zhang, H.

10.1101/865691 — neuroscience — Posted on 2020-01-31

99 Serum proteomics expands on high-affinity antibodies in immunized rabbits than deep B-cell repertoire sequencing alone

Bonissone, S. R.; Lima, T.; Harris, K.; Davison, L.; Avanzino, B.; Trinklein, N.; Castellana, N.; Patel, A.

10.1101/833871 — immunology — Posted on 2020-01-31

100 Decoding the genomic basis of osteoarthritis

Steinberg, J.; Southam, L.; Butterfield, N. C.; Roumeliotis, T. I.; Fontalis, A.; Clark, M. J.; Jayasuriya, R. L.; Swift, D.; Shah, K. M.; Curry, K. F.; Brooks, R. A.; McCaskie, A. W.; Lelliott, C. J.; Choudhary, J. S.; Bassett, J. D.; Williams, G. R.; Wilkinson, J. M.; Zeggini, E.

10.1101/835850 — genomics — Posted on 2020-01-31

101 Gene-by-environmental modulation of longevity and weight gain in the murine BXD family

Roy, S.; Sleiman, M. B.; Jha, P.; Williams, E. G.; Ingels, J. F.; Chapman, C. J.; McCarty, M. S.; Hook, M.; Sun, A.; Neuner, S.; Huang, J.; Zhao, W.; Centeno, A. G.; Kaczorowski, C. C.; Makowski, L.; Mozhui, K.; Mulligan, M. K.; Lu, L.; Read, R. W.; Sen, S.; Miller, R.; Auwerx, J.; Williams, R. W.

10.1101/776559 — genetics — Posted on 2020-01-31

102 Effect of nitrogen on fungal growth efficiency

Di Lonardo, D. P.; van der Wal, A.; Harkes, P.; de Boer, W.

10.1101/2020.01.19.911727 — ecology — Posted on 2020-01-31

103 The TMJ disc is a common ancestral feature in all mammals, as evidenced by the presence of a rudimentary disc during monotreme development.

Anthwal, N.; Tucker, A. S.

10.1101/2020.01.17.910471 — developmental biology — Posted on 2020-01-31

104 Wwc2 is a novel cell division/fate regulator during preimplantation mouse development and oogenesis

Virnicchi, G.; Bora, P.; Gahurova, L.; Susor, A.; Bruce, A. W.

10.1101/2019.12.12.872366 — developmental biology — Posted on 2020-01-31

105 An alternative spliceosome defined by distinct snRNAs in early zebrafish embryogenesis

Pagano, J. F. B.; Dekker, R. J.; Ensink, W. A.; van Olst, M.; Bos, A.; van Leeuwen, S.; de Leeuw, W. C.; Nehrdich, U.; Spaink, H. P.; Rauwerda, H.; Jonker, M. J.; Breit, T. M.

10.1101/858944 — developmental biology — Posted on 2020-01-31

106 Ultrafiltration Segregates Tissue Regenerative Stimuli Harboured Within and Independent of Extracellular Vesicles

Cooper, T. T.; Sherman, S. E.; Dayarathna, T.; Bell, G. I.; Ma, J.; McRae, D. M.; Lagugne-Labarthet, F.; Pasternak, S. H.; Lajoie, G. A.; Hess, D. A.

10.1101/2020.01.28.923037 — cell biology — Posted on 2020-01-31

107 Alternative splicing in neuroblastoma generates RNA-fusion transcripts and is associated with vulnerability to spliceosome inhibitors

Shi, Y.; Rraklli, V.; Maxymovitz, E.; Li, S.; Westerlund, I.; Reina, O. B.; Yuan, J.; Bullova, P.; Juhlin, C. C.; Stenman, A.; Larsson, C.; Kogner, P.; O'Sullivan, M. J.; Schlisio, S.; Holmberg, J.

10.1101/851238 — cancer biology — Posted on 2020-01-31

108 The Landscape of Mutations in Fumarate Hydratase

Shorthouse, D.; Hall, M. W. J.; Hall, B. A.

10.1101/852392 — biophysics — Posted on 2020-01-31

109 Expanding a Database-derived Biomedical Knowledge Graph via Multi-relation Extraction from Biomedical Abstracts

Nicholson, D. N.; Himmelstein, D. S.; Greene, C. S.

10.1101/730085 — bioinformatics — Posted on 2020-01-31

110 Eicosapentaenoic acid prevents obesity-induced metabolic impairments through the host-genetic dependent effects of resolvin E1

Pal, A.; Al-Shaer, A. E.; Guesdon, W.; Torres, M. J.; Armstrong, M.; Quinn, K.; Davis, T.; Reisdorph, N.; Neufer, P. D.; Spangenburg, E. E.; Carroll, I.; Bazinet, R. P.; Claria, J.; Shaikh, S. R.

10.1101/848093 — biochemistry — Posted on 2020-01-31

111 Circulating miR-181a-5p is a prognostic biomarker for amyotrophic lateral sclerosis

Magen, I.; Coenen-Stass, A. M. L.; Yacovzada, N.; Grosskreutz, J.; Lu, C.-H.; Greensmith, L.; Malaspina, A.; Fratta, P.; Hornstein, E.

10.1101/833079 — neuroscience — Posted on 2020-01-31

112 A ride in the park: Cycling in different outdoor environments modulates the auditory evoked potentials

Scanlon, J. E. M.; Redman, E. X.; Kuziek, J. W. P.; Mathewson, K. E.

10.1101/455394 — neuroscience — Posted on 2020-01-31

113 Mechanism of in vivo activation of the MutLγ-Exo1 complex for meiotic crossover formation

Sanchez, A.; Adam, C.; Rauh, F.; Duroc, Y.; Ranjha, L.; Lombard, B.; Mu, X.; Loew, D.; Keeney, S.; Cejka, P.; Guerois, R.; Klein, F.; Charbonnier, J.-B.; Borde, V.

10.1101/2019.12.16.876623 — molecular biology — Posted on 2020-01-31

114 Disruption of EGF feedback by intestinal tumors and neighboring cells in Drosophila

Ngo, S.; Liang, J.; Su, Y.-H.; O'Brien, L. E.

10.1101/541912 — developmental biology — Posted on 2020-01-31

115 The γH2AX Peak in the S Phase After UV Irradiation Corresponds to the sites of DNA Replication and not DNA Damage

Dhuppar, S.; Roy, S.; Mazumder, A.

10.1101/810689 — cell biology — Posted on 2020-01-31

116 Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats

Sajko, S.; Grishkovskaya, I.; Kostan, J.; Graewert, M.; Setiawan, K.; Truebestein, L.; Niedermuller, K.; Gehin, C.; Sponga, A.; Puchinger, M.; Gavin, A.-C.; Leonard, T.; Svergun, D. I.; Smith, T. K.; Morriswood, B. C.; Djinovic-Carugo, K.

10.1101/826180 — biochemistry — Posted on 2020-01-31

117 Pharmacological complementation remedies an inborn error of lipid metabolism

Hartley, M. D.; Shokat, M. D.; DeBell, M. J.; Banerji, T.; Kirkemo, L. L.; Scanlan, T. S.

10.1101/848119 — pharmacology and toxicology — Posted on 2020-01-31

118 Understanding psychophysiological interaction and its relations to beta series correlation

Di, X.; Zhang, Z.; Biswal, B. B.

10.1101/322073 — neuroscience — Posted on 2020-01-31

119 Temporal signatures of criticality in human cortical excitability as probed by early somatosensory responses

Stephani, T.; Waterstraat, G.; Haufe, S.; Curio, G.; Villringer, A.; Nikulin, V. V.

10.1101/809285 — neuroscience — Posted on 2020-01-31

120 Scalable generalized linear mixed model for region-based association tests in large biobanks and cohorts

Zhou, W.; Zhao, Z.; Nielsen, J. B.; Fritsche, L. G.; LeFaive, J.; Gagliano Taliun, S. A.; Bi, W.; Gabrielsen, M. E.; Daly, M. J.; Neale, B. M.; Hveem, K.; Abecasis, G. R.; Willer, C. J.; Lee, S.

10.1101/583278 — genetics — Posted on 2020-01-31

121 The evolution of competitive ability for essential resources

Bernhardt, J. R.; Kratina, P.; Pereira, A.; Tamminen, M.; Thomas, M. K.; Narwani, A.

10.1101/804542 — evolutionary biology — Posted on 2020-01-31

122 The evolution of realized niches within freshwater Synechococcus

Tromas, N.; Taranu, Z. E.; Castelli, M.; Pimentel, J. S. M.; Pereira, D. A.; Marcoz, R.; Shapiro, B. J.; Giani, A.

10.1101/678375 — ecology — Posted on 2020-01-31

123 Enzyme stoichiometry indicates the variation of microbial nutrient requirements at different soil depths in subtropical forests

Liu, J.; Chen, J.; Chen, G.; Guo, J.; Li, Y.

10.1101/711069 — ecology — Posted on 2020-01-31

124 Transects, quadrats, or points? What is the best combination to get a precise estimation of a coral community?

Montilla, L. M.; Miyazawa, E.; Ascanio, A.; Lopez-Hernandez, M. A.; Marino-Briceno, G.; Rebolledo, Z.; Rivera, A.; S. Mancilla, D.; Verde, A.; Croquer, A.

10.1101/832790 — ecology — Posted on 2020-01-31

125 Feedback loops involving AMPK, ERK and TFEB in matrix detachment leads to non-genetic heterogeneity

Kumar, S.; Hari, K.; Jolly, M. K.; Rangarajan, A.

10.1101/736546 — cancer biology — Posted on 2020-01-31

126 Productive lifespan and resilience rank can be predicted from on-farm first parity sensor time series but not using a common equation across farms

Adriaens, I.; Friggens, N. C.; Ouweltjes, W.; Scott, H.; Aernouts, B.; Statham, J.

10.1101/826099 — bioengineering — Posted on 2020-01-31

127 AMPK promotes Notch1 stability to potentiate hypoxia-induced breast cancer stemness and drug resistance

Lahiry, M.; Rangarajan, A.

10.1101/458489 — cancer biology — Posted on 2020-01-31

128 VIDHOP, viral host prediction with Deep Learning

Mock, F.; Viehweger, A.; Barth, E.; Marz, M.

10.1101/575571 — bioinformatics — Posted on 2020-01-31

129 Augmented base pairing networks encode RNA-small molecule binding preferences.

Oliver, C.; Mallet, V.; Sarrazin Gendron, R.; Reinharz, V.; Hamilton, W. L.; Moitessier, N.; Waldispuhl, J.

10.1101/701326 — bioinformatics — Posted on 2020-01-31

130 Soil variation response is mediated by growth trajectories rather than functional traits in a widespread pioneer Neotropical tree

Levionnois, S.; Tysklind, N.; Nicolini, E.; Ferry, B.; Troispoux, V.; Le Moguedec, G.; Morel, H.; Stahl, C.; Coste, S.; Caron, H.; Heuret, P.

10.1101/351197 — ecology — Posted on 2020-01-31

131 Rapid evolution of coordinated and collective movement in response to artificial selection

Kotrschal, A.; Szorkovszky, A.; Herbert Read, J.; Bloch, N.; Romenskyy, M.; Buechel, S. D.; Fontrodona, A.; Sanchez, L.; Zeng, H.; LeFoll, A.; Braux, G.; Pelckmans, K.; Mank, J. E.; Sumpter, D. J. T.; Kolm, N.

10.1101/2020.01.30.926311 — animal behavior and cognition — Posted on 2020-01-31

132 Efficient Exact Inference for Dynamical Systems with Noisy Measurements using Sequential Approximate Bayesian Computation

Schaelte, Y.; Hasenauer, J.

10.1101/2020.01.30.927004 — systems biology — Posted on 2020-01-31

133 The challenge of distinguishing cell-cell complexes from singlet cells in non-imaging flow cytometry and single-cell sorting

Burel, J. G.; Pozmanoy, M.; Lindestam Arlehamn, C. S.; Seumois, G.; Vijayanand, P.; Sette, A.; Peters, B.

10.1101/2020.01.30.927137 — immunology — Posted on 2020-01-31

134 Matrix-targeted Nanoparticles for MMP13 RNA Interference Blocks Post-Traumatic Osteoarthritis.

Bedingfield, S. K.; Yu, F.; Liu, D. D.; Jackson, M. A.; Himmel, L. E.; Cho, H.; Colazo, J. M.; Crofford, L. J.; Hasty, K. A.; Duvall, C. L.

10.1101/2020.01.30.925321 — bioengineering — Posted on 2020-01-31

135 Reducing shock imminence eliminates poor avoidance in rats

Laughlin, L.; Moloney, D.; Samels, S.; Sears, R.; Cain, C. K.

10.1101/2020.01.30.927152 — animal behavior and cognition — Posted on 2020-01-31

136 Single-cell transcriptome analyses recapitulate the cellular and developmental responses to abiotic stresses in rice

Wang, Y.; Huan, Q.; Chu, X.; Li, K.; Qian, W.

10.1101/2020.01.30.926329 — genomics — Posted on 2020-01-31

137 Impacts of predator-mediated interactions along a climatic gradient on the population dynamics of an alpine bird

Bowler, D.; Kvasnes, M.; Pedersen, H.; Sandercock, B. K.; Nilsen, E.

10.1101/2020.01.30.926212 — ecology — Posted on 2020-01-31

138 DREAM: A Toolbox to Decode Rhythms of the Brain System

Gong, Z.-Q.; Gao, P.; Xing, X.-X.; Jiang, C.; White, T. H.; Castellanos, F. X.; Li, H.-F.; Zuo, X.-N.

10.1101/2020.01.29.926204 — neuroscience — Posted on 2020-01-31

139 Population-specific FST and Pairwise FST: History and Environmental Pressure

Kitada, S.; Nakamichi, R.; Kishino, H.

10.1101/2020.01.30.927186 — evolutionary biology — Posted on 2020-01-31

140 Microbial trend analysis for common dynamic trend, group comparison and classification in longitudinal microbiome study

Wang, C.; Hu, J.; Blaser, M. J.; Li, H.

10.1101/2020.01.30.926824 — bioinformatics — Posted on 2020-01-31

141 Proteomics Using Protease Alternatives to Trypsin Benefits from Sequential Digestion with Trypsin

Dau, T.; Bartolomucci, G.; Rappsilber, J.

10.1101/2020.01.30.927046 — biochemistry — Posted on 2020-01-31

142 Sexually dimorphic responses to MPTP found in microglia, inflammation and gut microbiota in a progressive monkey model of Parkinson's disease

Joers, V.; Masilamoni, G.; Kempf, D. J.; Weiss, A. R.; Rotterman, T.; Murray, B.; Yalcin-Cakmakli, G.; Voll, R.; Goodman, M. M.; Howell, L.; Bachevalier, J.; Green, S.; Naqib, A.; Shaikh, M.; Engen, P.; Keshavarzian, A.; Barnum, C. J.; Nye, J. A.; Smith, Y.; Tansey, M. G.

10.1101/2020.01.30.925883 — neuroscience — Posted on 2020-01-31

143 Expression and purification of p72 trimers as subunit vaccine candidate

Meng, K.; Zhang, Y.; Zhu, W.; Xiang, Y.; Meng, G.

10.1101/2020.01.30.926808 — microbiology — Posted on 2020-01-31

144 Synteny-guided resolution of gene trees clarifies the functional impact of whole genome duplications

Parey, E.; Louis, A.; Cabau, C.; Guiguen, Y.; Roest Crollius, H.; Berthelot, C.

10.1101/2020.01.30.926915 — genomics — Posted on 2020-01-31

145 A litmus test for harmonized mosquito monitoring across Europe and Africa

Graziosi, I.; Aranda, C.; Balestrino, F.; Bellini, R.; Busquets, N.; Coulibaly, M.; Crisanti, A.; Diallo, D.; Diallo, M.; Gaye, A.; Guelbeogo, M.; Ignjatovic-Cupina, A.; Napp, S.; N'Fale, S.; Petric, D.; Pollegioni, P.; Simoni, A.; Zgomba, M.; Muller, R.

10.1101/2020.01.30.927020 — ecology — Posted on 2020-01-31

146 Selection and subsequent physiological characterisation of industrial Saccharomyces cerevisiae strains during continuous growth at sub- and- supra optimal temperatures

Lip, K. Y. F.; García-Ríos, E.; E. Costa, C.; Guillamon, J. M.; Domingues, L.; Teixeira, J.; van Gulik, W. M.

10.1101/2020.01.30.926709 — physiology — Posted on 2020-01-31

147 Perfluorooctanoic acid activates multiple nuclear receptor pathways and skews expression of genes regulating cholesterol homeostasis in liver of humanized PPARα mice fed an American diet

Schlezinger, J.; Puckett, H.; Oliver, J.; Nielsen, G.; Heiger-Bernays, W.; Webster, T.

10.1101/2020.01.30.926642 — pharmacology and toxicology — Posted on 2020-01-31

148 Semantic and Prosodic Threat Processing in Trait Anxiety: Is Repetitive Thinking Influencing Responses?

Busch Moreno, S.; Tuomainen, J.; Vinson, D.

10.1101/2020.01.24.918375 — neuroscience — Posted on 2020-01-31

149 Temporal expectation hastens sensory encoding but does not affect evidence quality

van den Brink, R. L.; Murphy, P. R.; Desender, K.; de Ru, N.; Nieuwenhuis, S.

10.1101/2020.01.30.926337 — neuroscience — Posted on 2020-01-31

150 Altered beta-band oscillations and connectivity underlie detail-oriented visual processing in autism

Ronconi, L.; Vitale, A.; Federici, A.; Pini, E.; Molteni, M.; Casartelli, L.

10.1101/2020.01.30.926261 — neuroscience — Posted on 2020-01-31

151 The functional foundations of episodic memory remain stable throughout the lifespan

Vidal-Pineiro, D.; Sneve, M. H.; Amlien, I. K.; Grydeland, H. H.; Mowinckel, A. M.; Roe, J. M.; Sorensen, O.; Nyberg, L. H.; Walhovd, K. B.; Fjell, A. M.

10.1101/2020.01.30.926469 — neuroscience — Posted on 2020-01-31

152 Interferon-γ signaling synergizes with LRRK2 in human neurons and microglia

De Cicco, S.; Ivanyuk, D.; Haq, W.; Panagiotakopoulou, V.; Arsic, A.; Schoendorf, D.; Yu, C.; Perez, M.-J.; Cassatella, R. P.; Jakobi, M.; Schneiderhan-Marra, N.; Nikic-Spiegel, I.; Gasser, T.; Deleidi, M.

10.1101/2020.01.30.925222 — neuroscience — Posted on 2020-01-31

153 The Neurovascular Basis of Postictal Amnesia

Farrell, J. S.; Colangeli, R.; Dudok, B.; Wolff, M. D.; Nguyen, S. L.; Dickson, C. T.; Soltesz, I.; Teskey, G. C.

10.1101/2020.01.30.926717 — neuroscience — Posted on 2020-01-31

154 Distinct midbrain response statistics are associated with sound recognition and discrimination during the construction of natural sound textures

Zhai, X.; Khatami, F.; Sadeghi, M.; He, F.; Read, H. L.; Stevenson, I. H.; Escabi, M.

10.1101/2020.01.30.914747 — neuroscience — Posted on 2020-01-31

155 Common default mode network dysfunction across psychopathologies: A neuroimaging meta-analysis of the n-back working memory paradigm

Farruggia, M.; Laird, A. R.; Mattfeld, A. T.

10.1101/2020.01.30.927210 — neuroscience — Posted on 2020-01-31

156 Plasticity of the glutamate transporter EAAT2 on striatal astrocytes regulates flexibility inbehavior

Boender, A. J.; Tonini, R.

10.1101/2020.01.30.927053 — neuroscience — Posted on 2020-01-31

157 Connectome-based predictive modeling of individual anxiety

Wang, Z.; S. Goerlich, K.; Ai, H.; Aleman, A.; Luo, Y.; Xu, P.

10.1101/2020.01.30.926980 — neuroscience — Posted on 2020-01-31

158 Csmd2 interacts with Dab1 and is Required in Reelin-Mediated Neuronal Maturation

Gutierrez, M. A.; Dwyer, B. E.; Franco, S. J.

10.1101/2020.01.30.925537 — neuroscience — Posted on 2020-01-31

159 Redox-active cysteines in TGACG-BINDING FACTOR 1 (TGA1) do not play a role in salicylic acid- or pathogen-induced expression of TGA1-regulated target genes in Arabidopsis thaliana

Budimir, J.; Treffon, K.; Nair, A.; Thurow, C.; Gatz, C.

10.1101/2020.01.30.926758 — molecular biology — Posted on 2020-01-31

160 Gold-standard diagnostics are tarnished by lytic bacteriophage

Nelson, E. J.; Grembi, J. A.; Chao, D. L.; Andrews, J. R.; Alexandrova, L.; Rodriguez, P. H.; Ramachandran, V. V.; Sayeed, M. A.; Wamala, J.; Debes, A. K.; Sack, D. A.; Hryckowian, A. J.; Haque, F.; Khatun, S.; Rahman, M. M.; Chien, A.; Spormann, A. M.; Schoolnik, G. K.

10.1101/2020.01.30.926832 — microbiology — Posted on 2020-01-31

161 The immune response and microbiota profiles during co-infection with P. vivax and soil-transmitted helminths

Easton, A. V.; Raciny-Aleman, M.; Liu, V.; Ruan, E.; Yasnot, M. F.; Rodriguez, A.; Loke, P.

10.1101/2020.01.30.925032 — microbiology — Posted on 2020-01-31

162 A plant pathogen utilizes effector proteins for microbiome manipulation

Snelders, N. C.; Rovenich, H.; Petti, G.; Rocafort, M.; Vorholt, J. A.; Mesters, J. R.; Seidl, M. F.; Nijland, R.; Thomma, B.

10.1101/2020.01.30.926725 — microbiology — Posted on 2020-01-31

163 Fitting drift-diffusion decision models to trial-by-trial data

Feltgen, Q.; Daunizeau, J.

10.1101/2020.01.30.925123 — animal behavior and cognition — Posted on 2020-01-31

164 HIV-1 Viremia Not Suppressible By Antiretroviral Therapy Can Originate from Large T-Cell Clones Producing Infectious Virus

Halvas, E. K.; Joseph, K.; Brandt, L. D.; Guo, S.; Sobolewski, M. D.; Jacobs, J. L.; Tumiotto, C.; Bui, J. K.; Cyktor, J. C.; Keele, B. F.; Morse, G. D.; Bale, M. J.; Kearney, M. F.; Coffin, J. M.; Rausch, J. W.; Wu, X.; Hughes, S. H.; Mellors, J. W.

10.1101/2020.01.30.924159 — genomics — Posted on 2020-01-31

165 Interpreting pathogen genetic diversity during measles epidemics

Worby, C.; Bozick, B.; Gastanaduy, P.; Yang, L.; Rota, P.; Grenfell, B.

10.1101/2020.01.30.926998 — evolutionary biology — Posted on 2020-01-31

166 Learning for angling: an advanced learning capability for avoidance of angling gear in red sea bream juveniles

Takahashi, K.; Masuda, R.

10.1101/2020.01.30.925875 — animal behavior and cognition — Posted on 2020-01-31

167 A Prokaryotic Membrane Sculpting BAR Domain Protein

Phillips, D. A.; Zacharoff, L. A.; Hampton, C. M.; Chong, G. W.; Malanoski, A. P.; Metskas, L. A.; Xu, S.; Bird, L. J.; Eddie, B. J.; Jensen, G. J.; Drummy, L. F.; El-Naggar, M. Y.; Glaven, S. M.

10.1101/2020.01.30.926147 — microbiology — Posted on 2020-01-31

168 Effect of 10 UV filters on the brine shrimp Artemia salina and the marine microalgae Tetraselmis sp.

Thorel, E.; Clergeaud, F.; Jaugeon, L.; Rodrigues, A.; Lucas, J.; Stien, D.; Lebaron, P.

10.1101/2020.01.30.926451 — ecology — Posted on 2020-01-31

169 Interaction of intraocular pressure and ganglion cell function in open angle glaucoma

Al-Nosairy, K. O.; Van den Bosch, J. J. O. N.; Pennisi, V.; Thieme, H.; Mansouri, K.; Choritz, L.; Hoffmann, M. B.

10.1101/2020.01.30.924290 — neuroscience — Posted on 2020-01-31

170 Does offspring sex ratio differ between urban and forest populations of great tits (Parus major)?

Agh, N.; Pipoly, I.; Szabo, K.; Vincze, E.; Bokony, V.; Seress, G.; Liker, A.

10.1101/2020.01.30.921106 — ecology — Posted on 2020-01-31

171 Triphenyl phosphate is a selective PPARγ modulator that does not induce brite adipogenesis in vitro and in vivo

Kim, S.; Rabhi, N.; Blum, B. C.; Hekman, R.; Wynne, K.; Emili, A.; Farmer, S.; Schlezinger, J. J.

10.1101/626390 — pharmacology and toxicology — Posted on 2020-01-31

172 Stratification of behavioral response to transcranial current stimulation by resting-state electrophysiology

Mastakouri, A. A.; Schoelkopf, B.; Grosse-Wentrup, M.

10.1101/2020.01.27.921668 — neuroscience — Posted on 2020-01-31

173 Telomere relocalization to the nuclear pore complex in response to replication stress

Pinzaru, A. M.; Lamm, N.; Al-Kareh, M.; Lazzerini-Denchi, E.; Cesare, A. J.; Sfeir, A.

10.1101/2020.01.31.929059 — molecular biology — Posted on 2020-01-31

174 The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells

Hoffmann, M.; Kleine-Weber, H.; Krueger, N.; Mueller, M. A.; Drosten, C.; Poehlmann, S.

10.1101/2020.01.31.929042 — molecular biology — Posted on 2020-01-31

175 Acetylation of cytidine residues boosts HIV-1 gene expression by increasing viral RNA stability

Tsai, K.; Vasudevan, A. A. J.; MartInez-Campos, C.; Emery, A.; Swanstrom, R.; Cullen, B. R.

10.1101/2020.01.31.925578 — microbiology — Posted on 2020-01-31

176 Current range of Agrilus planipennis Fairmaire, an alien pest of ash trees, in European Russia and Ukraine

Orlova-Bienkowskaja, M. J.; Drogvalenko, A. N.; Zabaluev, I. A.; Sazhnev, A. S.; Peregudova, E. Y.; Mazurov, S. G.; Komarov, E. V.; Struchaev, V. V.; Martynov, V. V.; Nikulina, T. V.; Bienkowski, A. O.

10.1101/689240 — ecology — Posted on 2020-01-31

177 Discovery of an evolutionarily conserved smooth muscle cell-specific lncRNA CARMN

Dong, K.; Shen, J.; He, X.; Wang, L.; Hu, G.; Bunting, K. M.; Dixon-Melvin, R.; Zheng, Z.; Xin, H.; Xiang, M.; Vazdarjanova, A.; Zhou, J.

10.1101/2020.01.30.927335 — developmental biology — Posted on 2020-01-31

178 Cytoprotection by a naturally occurring variant of ATP5G1 in Arctic ground squirrels

Singhal, N. S.; Bai, M.; Lee, E. M.; Luo, S.; Cook, K. R.; Ma, D. K.

10.1101/2020.01.31.929018 — cell biology — Posted on 2020-01-31

179 MTOC clustering and nuclear division through proper spindle positioning in yeast: a microtubule grow-and-catch model

Chatterjee, S.; Som, S.; Varshney, N.; Sanyal, K.; Paul, R.

10.1101/690651 — biophysics — Posted on 2020-01-31

180 Laboratory culture of the California Sea Firefly Vargula tsujii (Ostracoda: Cypridinidae): Developing a model system for the evolution of marine bioluminescence

Goodheart, J. A.; Minsky, G.; Brynjegard-Bialik, M. N.; Drummond, M. S.; Munoz, J. D.; Fallon, T. R.; Schultz, D. T.; Weng, J.-K.; Torres, E.; Oakley, T. H.

10.1101/708065 — developmental biology — Posted on 2020-01-31

181 Quantifying protein-protein interactions by molecular counting with mass photometry

Soltermann, F.; Foley, E. D. B.; Pagnoni, V.; Galpin, M. R.; Benesch, J. L. P.; Kukura, P.; Struwe, W. B.

10.1101/2020.01.31.925156 — biophysics — Posted on 2020-01-31

182 Machine learning approach reveals heterogeneous responses to FAK and Rho GTPases inhibition on smooth muscle spheroid formation

Vaidyanathan, K.; Wang, C.; Yu, Y.; Krajnik, A.; Choi, M.; Lin, B.; Kolega, J.; Lee, K.; Bae, Y.

10.1101/2020.01.30.927616 — cell biology — Posted on 2020-01-31

183 What the Zebrafish's Eye Tells the Zebrafish's Brain: Retinal Ganglion Cells for Prey Capture and Colour Vision

Zhou, M.; Bear, J. E.; Roberts, P. A.; Janiak, F. K.; Semmelhack, J.; Yoshimatsu, T.; Baden, T.

10.1101/2020.01.31.927087 — neuroscience — Posted on 2020-01-31

184 MRCA time and epidemic dynamics of the 2019 novel coronavirus

Zhang, C.; Wang, M.

10.1101/2020.01.25.919688 — microbiology — Posted on 2020-01-31

185 N6-methyladenosine in poly(A) tails stabilize VSG transcripts

Viegas, I. J.; Pereira de Macedo, J.; De Niz, M.; Rodrigues, J. A.; Aresta-Branco, F.; Jaffrey, S. R.; Figueiredo, L. M.

10.1101/2020.01.30.925776 — molecular biology — Posted on 2020-01-31

186 The activity of chloroplast NADH dehydrogenase-like complex influences the photosynthetic activity of the moss Physcomitrella patens

Storti, M.; Puggioni, M. P.; Segalla, A.; Morosinotto, T.; Alboresi, A.

10.1101/2020.01.29.924597 — plant biology — Posted on 2020-01-31

187 Population variation of miRNAs and isomiRs and their impact on human immunity to infection

Rotival, M.; Siddle, K. J.; Silvert, M.; Pothlichet, J.; Quach, H.; Quintana-Murci, L.

10.1101/2020.01.31.928580 — genomics — Posted on 2020-01-31

188 RNA secondary structure mediated by Alu insertion as a novel disease-causing mechanism

Masson, E.; Maestri, S.; Cooper, D. N.; Ferec, C.; Chen, J.-M.

10.1101/2020.01.30.926790 — genetics — Posted on 2020-01-31

189 Inducible epithelial resistance improves survival of Sendai virus pneumonia in mice by both inactivating virus and preventing CD8+ T cell-mediated immunopathology

Wali, S.; Flores, J. R.; Jaramillo, A. M.; Goldblatt, D. L.; Pantaleon Garcia, J.; Tuvim, M. J.; Dickey, B. F.; Evans, S. E.

10.1101/2020.01.30.917195 — immunology — Posted on 2020-01-31

190 Cannabinoid Biosynthesis using Noncanonical Cannabinoid Synthases

Go, M. K.; Lim, K. J. H.; Yew, W. S.

10.1101/2020.01.29.926089 — synthetic biology — Posted on 2020-01-31

191 Immunophenotyping of HER4/YAP axis in breast cancer brain metastasis

Kalita-de Croft, P.; Lim, M.; de Luca, X. M.; Day, B. W.; Saunus, J. M.; Lakhani, S. R.

10.1101/2020.01.29.924118 — pathology — Posted on 2020-01-31

192 Two-photon voltage imaging of spontaneous activity from multiple neurons reveals network activity in brain tissue

Li, B.; Chavarha, M.; Kobayashi, Y.; Yoshinaga, S.; Nakajima, K.; Lin, M.; Inoue, T.

10.1101/2020.01.29.926014 — neuroscience — Posted on 2020-01-31

193 Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene-dose-sensitive AD-suppressor in human brain

Alic, I.; Goh, P. A.; Murray, A.; Portelius, E.; Gkanatsiou, E.; Gough, G.; Mok, K. Y.; Koschut, D.; Brunmeir, R.; Yeap, Y. J.; O'Brien, N. L.; Groet, J.; Shao, X.; Havlicek, S.; Dunn, N. R.; Kvartsberg, H.; Brinkmalm, G.; Hithersay, R.; Startin, C.; Hamburg, S.; Phillips, M.; Pervushin, K.; Turmaine, M.; Wallon, D.; Rovelet-Lecrux, A.; Soininen, H.; Volpi, E.; Martin, J. E.; Foo, J. N.; Becker, D. L.; Rostagno, A.; Ghiso, J.; Krsnik, Z.; Simic, G.; Kostovic, I.; Mitrecic, D.; LonDownS Consortium, ; Francis, P. T.; Blennow, K.; Strydom, A.; Hardy, J.; Zetterberg, H.; Nizetic, D.

10.1101/2020.01.29.918037 — neuroscience — Posted on 2020-01-31

194 Using EEG to understand how our brain elaborate information in stated choice experiments: Easy versus hard tasks in the choice of vehicles

Cherchi, E.; Vuong, Q.; Stergiou, A.

10.1101/2020.01.29.926162 — neuroscience — Posted on 2020-01-31

195 Analysis of metagenome-assembled genomes from the mouse gut microbiota reveals distinctive strain-level characteristics

Li, S.; Zhang, S.; Li, B.; Sha, S.; Kang, J.; Li, P.; Zhang, A.; Ji, Q.; Lv, Q.; Zhang, X.-X.; Ni, H.; Han, X.; Xu, M.; Wang, G.; Zhang, W.; Sun, Y.; Xu, R.; Xin, Y.; Yan, Q.; Ma, Y.

10.1101/2020.01.29.926196 — microbiology — Posted on 2020-01-31

196 Germline genetic contribution to the immune landscape of cancer

Sayaman, R. W.; Saad, M.; Thorsson, V.; Hendrickx, W.; Roelands, J.; Mokrab, Y.; Farshidfar, F.; Kirchhoff, T.; Sweis, R. F.; Bathe, O. F.; Porta-Pardo, E.; Campbell, M. J.; Stretch, C.; Hu, D.; Huntsman, S.; Graff, R. E.; Syed, N.; Radvanyi, L.; Shelly, S.; Wolf, D.; Marincola, F. M.; Ceccarelli, M.; Galon, J.; Ziv, E.; Bedognetti, D.

10.1101/2020.01.30.926527 — immunology — Posted on 2020-01-31

197 The gut microbiota limits Th2 immunity to Heligmosomoides polygyrus bakeri infection

Russell, G. A.; Faubert, C.; Verdu, E. F.; King, I. L.

10.1101/2020.01.30.927111 — immunology — Posted on 2020-01-31

198 DNA polymerase β prevents AID-instigated mutagenic non-canonical mismatch DNA repair

Bahjat, M.; Stratigopoulou, M.; Pilzecker, B.; van Dam, T. P.; Mobach, S.; Bende, R. J.; van Noesel, C. J.; Jacobs, H. E.; Guikema, J. E.

10.1101/2020.01.30.926964 — immunology — Posted on 2020-01-31

199 Transposase assisted tagmentation of RNA/DNA hybrid duplexes

Yi, C.; Lu, B.; Dong, L.; Yi, D.; Zhu, C.; Zhang, M.; Li, X.

10.1101/2020.01.29.926105 — genomics — Posted on 2020-01-31

200 Pervasive phenotypic impact of a large non-recombining introgressed region in yeast

Brion, C.; Caradec, C.; Pflieger, D.; Friedrich, A.; Schacherer, J.

10.1101/2020.01.29.925289 — genetics — Posted on 2020-01-31

201 The genetic structure and adaptation of Andean highlanders and Amazonian dwellers is influenced by the interplay between geography and culture

Borda, V.; Alvim, I.; Aquino, M. M.; Silva, C.; Soares-Souza, G. B.; Leal, T. P.; Scliar, M. O.; Zamudio, R.; Zolini, C.; Padilla, C.; Caceres, O.; Levano, K.; Sanchez, C.; Trujillo, O.; Flores-Villanueva, P.; Dean, M.; Fuselli, S.; Machado, M.; Romero, P. E.; Tassi, F.; Yeager, M.; O'Connor, T. D.; Gilman, R. H.; Tarazona-Santos, E.; Guio, H.

10.1101/2020.01.30.916270 — evolutionary biology — Posted on 2020-01-31

202 VarFish - Collaborative and Comprehensive Variant Analysis for Diagnosis and Research

Holtgrewe, M.; Stolpe, O.; Nieminen, M.; Mundlos, S.; Knaus, A.; Kornak, U.; Seelow, D.; Segebrecht, L.; Spielmann, M.; Fischer-Zirnsak, B.; Boschann, F.; Scholl, U.; Ehmke, N.; Beule, D.

10.1101/2020.01.27.921965 — bioinformatics — Posted on 2020-01-31

203 Mutational effects on carbapenem hydrolysis of YEM-1, a new sub-class B2 metallo-β-lactamase from Yersinia mollaretii

Mercuri, P. S.; Esposito, R.; Bletard, S.; Di Costanzo, S.; Perilli, M. G.; Kerff, F.; Galleni, M.

10.1101/2020.01.29.926220 — biochemistry — Posted on 2020-01-31

204 The crystal structure of the TonB-dependent transporter YncD reveals a positively charged substrate binding site.

Grinter, R.; Lithgow, T.

10.1101/2020.01.29.925891 — biochemistry — Posted on 2020-01-31

205 Wide-vergence, multi-spectral adaptive optics scanning laser ophthalmoscope with diffraction-limited illumination and collection

Mozaffari, S.; LaRocca, F.; Jaedicke, V.; Tiruveedhula, P.; Roorda, A.

10.1101/2020.01.29.924969 — bioengineering — Posted on 2020-01-31

206 VARIATION AND SELECTION IN AXON NAVIGATION THROUGH MICROTUBULE-DEPENDENT STEPWISE GROWTH CONE ADVANCE

Turney, S. G.; Chandrasekar, I.; Ahmed, M.; Rioux, R. M.; Whitesides, G. M.; Bridgman, P. C.

10.1101/2020.01.29.925602 — neuroscience — Posted on 2020-01-31

207 Coupling of Ca2+ and voltage activation in BK channels through the αB helix/voltage sensor interface

Geng, Y.; Deng, Z.; Zhang, G.; Budelli, G.; Butler, A.; Yuan, P.; Cui, J.; Salkoff, L.; Magleby, K. L.

10.1101/2020.01.29.925545 — neuroscience — Posted on 2020-01-31

208 MinION-based DNA barcoding of preserved and non-invasively collected wildlife samples

Seah, A.; Lim, M. C. W.; McAloose, D.; Prost, S.; Seimon, T.

10.1101/2020.01.29.925081 — molecular biology — Posted on 2020-01-31

209 Pdap1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification

Delgado-Benito, V.; Berruezo-Llacuna, M.; Altwasser, R.; Winkler, W.; Balasubramanian, S.; Sundaravinayagam, D.; Graf, R.; Rahjouei, A.; Driesner, M.; Keller, L.; Janz, M.; Akalin, A.; Di Virgilio, M.

10.1101/2020.01.30.917062 — immunology — Posted on 2020-01-31

210 The digestive system is a potential route of 2019-nCov infection: a bioinformatics analysis based on single-cell transcriptomes

Zhang, H.; Kang, Z.; Gong, H.; Xu, D.; Wang, J.; Li, Z.; Cui, X.; Xiao, J.; Meng, T.; Zhou, W.; Liu, J.; Xu, H.

10.1101/2020.01.30.927806 — microbiology — Posted on 2020-01-31

Pradhan, P.; Pandey, A. K.; Mishra, A.; Gupta, P.; Tripathi, P. K.; Menon, M. B.; Gomes, J.; Vivekanandan, P.; Kundu, B.

10.1101/2020.01.30.927871 — evolutionary biology — Posted on 2020-01-31

212 Maintaining oxidized H3 in heterochromatin is required for the oncogenic capacity of triple-negative breast cancer cells

Serra-Bardenys, G.; Tian, T. V.; Blanco, E.; Querol, J.; Pascual-Reguant, L.; Morancho, B.; Escorihuela, M.; Segura-Bayona, S.; Verde, G.; Aiese Cigliano, R.; Millanes-Romero, A.; Jerónimo, C.; Nuciforo, P.; Simonetti, S.; Viaplana, C.; Dienstmann, R.; Saura, C.; Peg, V.; Stracker, T. H.; Arribas, J.; Villanueva, J.; Di Croce, L.; García de Herreros, A.; Peiró, S.

10.1101/2020.01.30.927038 — cancer biology — Posted on 2020-01-31

213 A Unified De Novo Approach for Predicting the Structures of Ordered and Disordered Proteins

Ferrie, J. J.; Petersson, E. J.

10.1101/2020.01.30.925636 — biophysics — Posted on 2020-01-31

214 Microglia in the developing retina couple phagocytosis with the progression of apoptosis via P2RY12 signaling

Blume, Z. I.; Lambert, J. M.; Lovel, A. G.; Mitchell, D. M.

10.1101/2020.01.30.925859 — developmental biology — Posted on 2020-01-31

215 dnmt1 function is required to maintain retinal stem cells within the ciliary marginal zone of the zebrafish eye

Angileri, K. M.; Gross, J.

10.1101/2020.01.29.925784 — developmental biology — Posted on 2020-01-31

216 The Mutational Landscape of the SCAN-B Real-World Primary Breast Cancer Transcriptome

Brueffer, C.; Gladchuk, S.; Winter, C.; Vallon-Christersson, J.; Hegardt, C.; Häkkinen, J.; George, A. M.; Chen, Y.; Ehinger, A.; Larsson, C.; Loman, N.; Malmberg, M.; Ryden, L.; Borg, A.; Saal, L. H.

10.1101/2020.01.30.926733 — cancer biology — Posted on 2020-01-31

217 Structural asymmetry governs the assembly and GTPase activity of McrBC restriction complexes

Niu, Y.; Suzuki, H.; Hosford, C. J.; Walz, T.; Chappie, J. S.

10.1101/2020.01.30.927467 — biochemistry — Posted on 2020-01-31

218 Unraveling the Mechanism of a LOV Domain Optogenetic Sensor: A Glutamine Lever Induces Unfolding of the Jα Helix

Iuliano, J. N.; Tolentino Collado, J.; Gil, A. A.; Ravindran, P. V.; Lukacs, A.; Shin, S.; Woroniecka, H. A.; Adamczyk, K.; Aramini, J. M.; Edupuganti, U. R.; Hall, C. R.; Greetham, G. M.; Sazanovich, I. V.; Clark, I. P.; Daryaee, T.; Toettcher, J. E.; French, J. B.; Gardner, K. H.; Simmerling, C. L.; Meech, S. R.; Tonge, P. J.

10.1101/2020.01.29.925040 — biophysics — Posted on 2020-01-31

219 MAGGIE: leveraging genetic variation to identify DNA sequence motifs mediating transcription factor binding and function

Shen, Z.; Hoeksema, M.; Ouyang, Z.; Benner, C.; Glass, C.

10.1101/2020.01.30.925917 — bioinformatics — Posted on 2020-01-31

220 Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

Rut, W.; Zmudzinski, M.; Snipas, S. J.; Bekes, M.; Huang, T. T.; Drag, M.

10.1101/2020.01.30.926881 — biochemistry — Posted on 2020-01-31

221 Differentiation genes were governed by DNA methylation during hair follicle morphogenesis in Cashmere goat

Wang, S.; Li, F.; Liu, J.; Zhang, Y.; Zheng, Y.; Ge, W.; Qu, L.; Wang, X.

10.1101/2020.01.30.926360 — developmental biology — Posted on 2020-01-31

222 Endothelial TGF-β signaling instructs smooth muscle development in the cardiac outflow tract

Boezio, G. L. M.; Bensimon-Brito, A.; Piesker, J.; Guenther, S.; Helker, C. S. M.; Stainier, D. Y. R.

10.1101/2020.01.30.925412 — developmental biology — Posted on 2020-01-31

223 A single-cell transcriptome atlas during Cashmere goat hair follicle morphogenesis

Ge, W.; Zhang, W.-D.; Zhang, Y.-L.; Zheng, Y.-J.; Li, F.; Wang, S.-H.; Liu, J.-W.; Tan, S.-J.; Yan, Z.-H.; Wang, L.; Shen, W.; Qu, L.; Wang, X.

10.1101/2020.01.30.926287 — developmental biology — Posted on 2020-01-31

224 Rab10 Regulates Macropinocytosis in Phagocytes

Liu, Z.; Xu, E.; Zhao, H.; Cole, T.; West, A. B.

10.1101/2020.01.30.926840 — cell biology — Posted on 2020-01-31

225 AVP-induced counter-regulatory glucagon is diminished in type 1 diabetes

Kim, A.; Knudsen, J. G.; Madara, J. C.; Benrick, A.; Hill, T.; Abdul Kadir, L.; Kellard, J. A.; Mellander, L.; Miranda, C.; Lin, H.; James, T.; Suba, K.; Spigelman, A.; Wu, Y.; MacDonald, P.; Wernstedt Asterholm, I.; Magnussen, T.; Christensen, M.; Visboll, T.; Salem, V.; Knop, F. K.; Rorsman, P.; Lowell, B. B.; Briant, L.

10.1101/2020.01.30.927426 — cell biology — Posted on 2020-01-31

226 Identification of Relevant Genetic Alterations in Cancer using Topological Data Analysis

Rabadan, R.; Mohamedi, Y.; Rubin, U.; Chu, T.; Elliott, O.; Arnes, L.; Cal, S.; Obaya, A. J.; Levine, A. J.; Camara, P. G.

10.1101/2020.01.30.922310 — cancer biology — Posted on 2020-01-31

227 Intrinsically disordered domain of kinesin-3 Kif14 enables unique functional diversity

Zhernov, I.; Diez, S.; Braun, M.; Lansky, Z.

10.1101/2020.01.30.926501 — biophysics — Posted on 2020-01-31

228 Systematic Normalization with Multiple Housekeeping Genes for the Discovery of Genetic Dependencies in Cancer

Bonham-Carter, O.; Thu, Y. M.

10.1101/2020.01.29.925651 — bioinformatics — Posted on 2020-01-31

229 metaVaR: introducing metavariant species models for reference-free metagenomic-based population genomics

Laso-Jadart, R.; Ambroise, C.; Peterlongo, P.; Madoui, M.-A.

10.1101/2020.01.30.924381 — bioinformatics — Posted on 2020-01-31

230 CopyMix: Mixture Model Based Single-Cell Clustering and Copy Number Profiling using Variational Inference

Safinianaini, N.; P. E. de Souza, C.; Lagergren, J.

10.1101/2020.01.29.926022 — bioinformatics — Posted on 2020-01-31

231 Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors

Gerner-Mauro, K. N.; Akiyama, H.; Chen, J.

10.1101/2020.01.29.925842 — developmental biology — Posted on 2020-01-31

232 Lnc-ECAL-1 controls cerebrovascular homeostasis by targeting endothelium-specific tight junction protein Cldn5b

Li, F.-F.; Liang, Y.-L.; Zhang, J.-J.; Jing, Q.

10.1101/2020.01.30.926279 — developmental biology — Posted on 2020-01-31

233 Excess crossovers impede faithful meiotic chromosome segregation in C. elegans

Hollis, J. A.; Glover, M. L.; Schlientz, A.; Cahoon, C. K.; Bowerman, B.; Wignall, S. M.; Libuda, D. E.

10.1101/2020.01.30.927640 — cell biology — Posted on 2020-01-31

234 Influenza hemagglutinin drives viral entry via two sequential intramembrane mechanisms

Pabis, A.; Rawle, R. J.; Kasson, P. M.

10.1101/2020.01.30.926816 — biophysics — Posted on 2020-01-31

235 The Effect of Kinship in Re-identification Attacks Against Genomic Data Sharing Beacons

Aysen, M.; Ayday, E.; Cicek, A. E.

10.1101/2020.01.30.926907 — bioinformatics — Posted on 2020-01-31

236 Matrix factorization and transfer learning uncover regulatory biology across multiple single-cell ATAC-seq data sets

Erbe, R.; Kess;ler, M. D.; Favorov, A. V.; Easwaran, H.; Gaykalova, D. A.; Fertig, E. J.

10.1101/2020.01.30.927129 — bioinformatics — Posted on 2020-01-31

237 Expression changes confirm genomic variants predicted to result in allele-specific, alternative mRNA splicing

Mucaki, E. J.; Shirley, B. C.; Rogan, P. K.

10.1101/549089 — genomics — Posted on 2020-01-31

238 Valid and powerful group statistics for decoding accuracy: Information Prevalence Inference using the i-th order statistic (i-test)

Hirose, S.

10.1101/578930 — neuroscience — Posted on 2020-01-31

239 Genomic basis of transcriptome dynamics in rice under field conditions

Kashima, M.; Sakamoto, R. L.; Saito, H.; Ohkubo, S.; Tezuka, A.; Deguchi, A.; Hashida, Y.; Kurita, Y.; Iwayama, K.; Adachi, S.; Nagano, A. J.

10.1101/451609 — bioinformatics — Posted on 2020-01-31

240 Investigating Population-scale Allele Specific Expression in Wild Populations of Oithona similis (Cyclopoida, Claus 1866)

Laso-Jadart, R.; Sugier, K.; Petit, E.; Labadie, K.; Peterlongo, P.; Ambroise, C.; Wincker, P.; Jamet, J.-L.; Madoui, M.-A.

10.1101/599076 — genomics — Posted on 2020-01-31

241 Too Close to Eat? Solidarity with Animals, Animal Welfare and Meat Consumption

Boaitey, A.; Jette Nantel, S.; Eden, M.

10.1101/2020.01.30.926592 — scientific communication and education — Posted on 2020-01-30

242 Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model

Ndungu, K.; Murilla, G. A.; Thuita, J. K.; Ngae, G. N.; Auma, J. E.; Gitonga, P. K.; Kahiga, D. T.; Kurgat, R. K.; Chemuliti, J. K.; Mdachi, R. E.

10.1101/2020.01.30.926675 — pathology — Posted on 2020-01-30

243 Niche preference of Escherichia coli in a peri-urban pond ecosystem

NandaKafle, G.; Haugen, T.; Potgieter, S. C.; Steenkamp, E.; Venter, S. N.; Brozel, V.

10.1101/2020.01.30.926667 — microbiology — Posted on 2020-01-30

244 Fingerprinting of hatchery haplotypes by whole-mitogenome sequencing improves genetic studies of masu salmon Oncorhynchus masou masou

Kato-Unoki, Y.; Umemura, K.; Tashiro, K.

10.1101/2020.01.30.926691 — genetics — Posted on 2020-01-30

245 Transferability, development of Single Sequence Repeat (SSR) markers and application to the analysis of genetic diversity and population structure of the African fan palm (Borassus aethiopum Mart.) in Benin

Kpatenon, M. J.; Salako, V. K.; Santoni, S.; Zekraoui, L.; Latreille, M.; Tollon-Cordet, C.; Mariac, C.; Jaligot, E.; Beule, T.; ADEOTI, K.

10.1101/2020.01.30.926626 — genetics — Posted on 2020-01-30

246 Passive acoustic methods for tracking the 3D movements of small cetaceans around marine structures

Gillespie, D.; Palmer, L. E.; Macaulay, J.; Sparling, C.; Hastie, G.

10.1101/2020.01.30.926659 — ecology — Posted on 2020-01-30

247 Robust design capture-recapture analysis of abundance and demographic parameters of Indian River Lagoon common bottlenose dolphins (Tursiops truncatus truncatus)

Durden, W. N.; Stolen, E. D.; Moreland, L.; Howells, E.; Jablonski, T.; Sleeman, A.; Denny, M.; Biedenbach, G.; Mazzoil, M.

10.1101/2020.01.30.926683 — ecology — Posted on 2020-01-30

248 Improving Heart disease risk through quality-focused diet logging: pre-post study of a diet quality tracking app

VanDam, C.; Kwon, B. C.; Chiuve, S.; Choi, H.-W.; Entler, P.; Tan, P.-N.; Huh-Yoo, J.

10.1101/2020.01.30.926634 — bioinformatics — Posted on 2020-01-30

249 Combined impact of pesticides and other environmental stressors on taxonomic richness of freshwater animals in irrigation ponds

Ito, H.; Shiraishi, H.; Nakagawa, M.; Takamura, N.

10.1101/2020.01.30.926568 — ecology — Posted on 2020-01-30

250 Effects of scent lure on camera trap detections vary across mammalian predator and prey species

Holinda, D.; Burgar, J.; Burton, C.

10.1101/2020.01.30.926618 — ecology — Posted on 2020-01-30

251 Conventional dose rate spatially-fractionated radiation therapy (SFRT) treatment response and its association with dosimetric parameters - A preclinical study in a Fisher 344 rat model

Rivera, J. N.; Kierski, T. M.; Kasoji, S. K.; Abrantes, A. S.; Dayton, P. A.; Chang, S.

10.1101/2020.01.30.926576 — cancer biology — Posted on 2020-01-30

252 Evolution and variation of 2019-novel coronavirus

Xiong, C.; Jiang, L.; Chen, Y.; Jiang, Q.

10.1101/2020.01.30.926477 — microbiology — Posted on 2020-01-30

253 Cell polarisation in a bulk-surface model can be driven by both classic and non-classic Turing instability

Borgqvist, J.; Malik, A.; Lundholm, C.; Logg, A.; Gerlee, P.; Cvijovic, M.

10.1101/2020.01.29.925628 — systems biology — Posted on 2020-01-30

254 Tailored Design of Protein Nanoparticle Scaffolds for Multivalent Presentation of Viral Glycoprotein Antigens

Ueda, G.; Antanasijevic, A.; Fallas, J. A.; Sheffler, W.; Copps, J.; Ellis, D.; Hutchinson, G.; Moyer, A.; Yasmeen, A.; Tsybovsky, Y.; Park, Y.-J.; Bick, M. J.; Sankaran, B.; Gillespie, R. A.; Brouwer, P. J.; Zwart, P. H.; Veesler, D.; Kanekiyo, M.; Graham, B. S.; Sanders, R. W.; Moore, J. P.; Klasse, P. J.; Ward, A.; King, N.; Baker, D.

10.1101/2020.01.29.923862 — synthetic biology — Posted on 2020-01-30

255 Reconstituted Mining Effluent Reduces Neuronal Proliferation in the Developing Brain and Slows Growth of Body and Facial Features in Wild-Caught Wood Frog Tadpoles.

Sturgeon, H. G.; Kitchen, J. P.; Dahora, L. I.; Sweeten, S. E.; Thompson, C. K.

10.1101/2020.01.29.924837 — pharmacology and toxicology — Posted on 2020-01-30

256 Effects of rhein on bile acid homeostasis in rats

Xian, Z.; Tian, J.; Wang, L.; Zhang, Y.; Han, J.; Deng, N.; Liu, S.; Zhao, Y.; Li, C.; Yi, Y.; Wang, D.; Meng, J.; Pan, C.; Liang, A.

10.1101/2020.01.29.925297 — pharmacology and toxicology — Posted on 2020-01-30

257 Long term AAV2/9-mediated silencing of PMP22 prevents CMT1A disease in rats and validates skin biomarkers as treatment outcome measure

Gautier, B.; Hajjar, H.; Soares, S.; Berthelot, J.; Deck, M.; Abbou, S.; Campbell, G.; Fovet, C.-M.; Schuetza, V.; Jouvenel, A.; Rivat, C.; Zerah, M.; Le Razavet, V.; Le Guiner, C.; Aubourg, P.; Fledrich, R.; Tricaud, N.

10.1101/2020.01.29.924605 — neuroscience — Posted on 2020-01-30

258 Cortical surface alterations in cingulate and frontal regulatory areas underlies insensitive mothering

Leon, I.; Rodrigo, M. J.; Quinones, I.; Hernandez-Cabrera, J. A.; Garcia-Penton, L.

10.1101/2020.01.29.924613 — neuroscience — Posted on 2020-01-30

259 The dynamics of the improvising brain: a study of musical creativity using jazz improvisation

Da Mota, P. A.; Fernandes, H. M.; Stark, E.; Cabral, J.; Heggli, O. A.; Sousa, N.; Kringelbach, M. L.; Vuust, P.

10.1101/2020.01.29.924415 — neuroscience — Posted on 2020-01-30

260 The role of the cingulate cortex in the generation of motor tics and the experience of the premonitory urge-to-tic in Tourette syndrome

Jackson, S. R.; Sigurdsson, H. P.; Dyke, K.; Condon, M.; Jackson, G. M.

10.1101/2020.01.29.924399 — neuroscience — Posted on 2020-01-30

261 The Maryland Analysis of Developmental EEG (MADE) Pipeline

Debnath, R.; Buzzell, G. A.; Morales, S.; Bowers, M. E.; Leach, S. C.; Fox, N. A.

10.1101/2020.01.29.925271 — neuroscience — Posted on 2020-01-30

262 mSWI/SNF promotes distal repression by titrating polycomb dosage

Weber, C. M.; Hafner, A.; Braun, S. M. G.; Boettiger, A. N.; Crabtree, G. R.

10.1101/2020.01.29.925586 — molecular biology — Posted on 2020-01-30

263 microRNA-seq of cartilage reveals an over-abundance of miR-140-3p which contains functional isomiRs

Woods, S.; Charlton, S.; Cheung, K.; Hao, Y.; Soul, J.; Reynard, L. N.; Crowe, N.; Swingler, T. E.; Skelton, A. J.; Pirog, K. A.; Miles, C. G.; Tsompani, D.; Jackson, R. M.; Dalmay, T.; Clark, I. M.; Barter, M. J.; Young, D. A.

10.1101/2020.01.29.925206 — molecular biology — Posted on 2020-01-30

264 The impediment to replication at tRNA genes in S. cerevisiae does not require tRNA transcription, and is facilitated by topoisomerases and Rad18-dependent repair pathways

Yeung, R.; Smith, D. J.

10.1101/2020.01.29.925644 — molecular biology — Posted on 2020-01-30

265 A novel fibrinogen gamma-chain mutation, p. γAla327Val, causes structural abnormality of D region and ultimately leads to congenital dysfibrinogenemia

Wei, A.; Wu, Y.; Xiang, L.; Yan, J.; Cheng, P.; Deng, D.; Lin, F.

10.1101/2020.01.29.925172 — molecular biology — Posted on 2020-01-30

266 Sox2 and canonical Wnt signaling interact to activate a developmental checkpoint coordinating morphogenesis with mesodermal fate acquisition

Kinney, B. A.; Row, R. H.; Tseng, Y.-J.; Weidmann, M. D.; Knaut, H.; Martin, B. L.

10.1101/2020.01.29.924050 — developmental biology — Posted on 2020-01-30

267 Biofilms mechanically damage epithelia by buckling.

Cont, A.; Rossy, T.; Al-Mayyah, Z.; Persat, A.

10.1101/2020.01.29.923060 — microbiology — Posted on 2020-01-30

268 A rapidly evolved shift in life history timing during ecological speciation is driven by the transition between developmental phases

Powell, T. H.; Nguyen, A. D.; Xia, Q.; Feder, J. L.; Ragland, G. J.; Hahn, D. A.

10.1101/2020.01.29.925057 — evolutionary biology — Posted on 2020-01-30

269 The proteasomal deubiquitinating enzyme PSMD14 regulates macroautophagy by controlling Golgi-to-ER retrograde transport

Bustamante, H.; Cereceda, K.; Gonzalez, A.; Valenzuela, G.; Cheuquemilla, Y.; Hernandez, S.; Arias, E.; Kerr, B.; Mardones, G.; Cancino, J.; Hay, R.; Rojas, A.; Burgos, P.

10.1101/2020.01.29.925503 — cell biology — Posted on 2020-01-30

270 Nucleolar disruption, activation of P53 and premature senescence in POLR3A-mutated Wiedemann-Rautenstrauch Syndrome fibroblasts

Baez, C. T.; Valencia, E.; Velasquez, K.; Ramirez, N.; Guevara, C.; Sandoval-Hernandez, A.; Arboleda-Bustos, C.; Olivos-Cisneros, L.; Gutierrez-Ospina, G.; Arboleda, H.; Arboleda, G.

10.1101/2020.01.29.925131 — cell biology — Posted on 2020-01-30

271 Spatial distribution and hotspots of mammals in Canada

Cameron, V.; Hargreaves, A. L.

10.1101/2020.01.29.925461 — ecology — Posted on 2020-01-30

272 Bi-fated tendon-to-bone attachment cells are regulated by shared enhancers and KLF transcription factors

Kult, S.; Zelzer, E.; Olender, T.; Osterwalder, M.; Krief, S.; Blecher-Gonen, R.; Ben-Moshe, S.; Farack, L.; Keren-Shaul, H.; Leshkowitz, D.; Salame, T.-M.; Capellini, T. D.; Itzkovitz, S.; Amit, I.; Visel, A.

10.1101/2020.01.29.924654 — developmental biology — Posted on 2020-01-30

273 Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA

Madru, C.; Raia, P.; Hugonneau-Beaufet, I.; Pehau-Arnaudet, G.; England, P.; Lindahl, E.; Delarue, M.; Carroni, M.; Sauguet, L.

10.1101/2020.01.29.925263 — biochemistry — Posted on 2020-01-30

274 Germinal center B cells separate signals for selectionand division like compact discs

Meyer-Hermann, M.

10.1101/2020.01.29.925479 — immunology — Posted on 2020-01-30

275 Taking population stratification into account by local permutations in rare-variant association studies on small samples

Mullaert, J.; Bouaziz, M.; Seeleuthner, Y.; Bigio, B.; Casanova, J.-L.; Alcais, A.; Abel, L.; Cobat, A.

10.1101/2020.01.29.924977 — genomics — Posted on 2020-01-30

276 Global change adaptation limits future resilience

Brennan, R. S.; deMayo, J. A.; Dam, H. G.; Finiguerra, M.; Baumann, H.; Pespeni, M. H.

10.1101/2020.01.29.925396 — evolutionary biology — Posted on 2020-01-30

277 Theoretical guidelines for editing ecological communities

Nguyen, V.; Vural, D. C.

10.1101/2020.01.29.925693 — ecology — Posted on 2020-01-30

278 Clustering of dispersal corridors in metapopulations leads to higher rates of recovery following subpopulation extinction

Kurkjian, H. M.

10.1101/2020.01.29.925529 — ecology — Posted on 2020-01-30

279 Symbiosis between river and dry lands: phycobiont dynamics on river gravel bars

Vancurova, L.; Kalnikova, V.; Peksa, O.; Skvorova, Z.; Malicek, J.; Moya, P.; Chytry, K.; Cernajova, I.; Skaloud, P.

10.1101/2020.01.29.924803 — ecology — Posted on 2020-01-30

280 Growth of the Fucus embryo: insights into wall-mediated cell expansion through mechanics and transcriptomics

Linardic, M.; Cokus, S. J.; Pellegrini, M.; Braybrook, S. A.

10.1101/2020.01.29.925107 — developmental biology — Posted on 2020-01-30

281 A Reporter Mouse for In Vivo Detection of DNA Damage in Embryonic Germ Cells

Bloom, J. C.; Schimenti, J. C.

10.1101/2020.01.29.925487 — cell biology — Posted on 2020-01-30

282 Molecular mechanism of light-driven sodium pumping

Kovalev, K.; Astashkin, R.; Gushchin, I.; Orekhov, P.; Volkov, D.; Zinovev, E.; Marin, E.; Rulev, M.; Alekseev, A.; Royant, A.; Carpentier, P.; Vaganova, S.; Baeken, C.; Sergeev, I.; Zabelskii, D.; Balandin, T.; Bourenkov, G.; Borshchevskiy, V.; Bueldt, G.; Bamberg, E.; Gordeliy, V.

10.1101/2020.01.29.925347 — biophysics — Posted on 2020-01-30

283 Correlation guided Network Integration (CoNI) reveals novel genetic regulators of hepatic metabolism

10.1101/2020.01.29.924944 — bioinformatics — Posted on 2020-01-30

284 The role of group I p21-activated kinases in contraction-stimulated skeletal muscle glucose transport

Moller, L. L. V.; Nielsen, I. L.; Knudsen, J. R.; Andersen, N. R.; Jensen, T. E.; Sylow, L.; Richter, E. A.

10.1101/2020.01.29.925024 — cell biology — Posted on 2020-01-30

285 Multisensory perception, verbal, visuo-spatial and motor working memory modulation after a single open- or closed-skill exercise session in children.

O'Brien, J.; Ottoboni, G.; Tessari, A.; Setti, A.

10.1101/2020.01.29.924563 — animal behavior and cognition — Posted on 2020-01-30

286 Suspensor-derived somatic embryogenesis in Arabidopsis

Radoeva, T.; Albrecht, C.; Piepers, M.; de Vries, S. C.; Weijers, D.

10.1101/2020.01.29.924621 — plant biology — Posted on 2020-01-30

287 Observed but Never Experienced - Vicarious Learning of Fear Under Ecological Conditions

Szczepanik, M.; Kazmierowska, A. M.; Michałowski, J. M.; Wypych, M.; Olsson, A.; Knapska, E.

10.1101/2020.01.29.924720 — neuroscience — Posted on 2020-01-30

288 Prefrontal state fluctuations control access to consciousness

Dwarakanath, A.; Kapoor, V.; Werner, J.; Safavi, S.; Fedorov, L.; Logothetis, N. K.; Panagiotaropoulos, T. I.

10.1101/2020.01.29.924928 — neuroscience — Posted on 2020-01-30

289 Factorial study of the RNA-seq computational workflow identifies biases as technical gene signatures

Simoneau, J.; Gosselin, R.; Scott, M. S.

10.1101/2020.01.30.924092 — bioinformatics — Posted on 2020-01-30

290 Effect of irradiation on the survival and susceptibility of female Anopheles arabiensis to natural isolates of Plasmodium falciparum

Guissou, E.; Poda, S.; Hien, F. d. S. D.; Yerbanga, S. R.; Da, D. F. Y.; Cohuet, A.; Fournet, F.; Roux, O.; Maiga, H.; Diabate, A.; Gilles, J.; Bouyer, J.; Ouedraogo, G. A.; Rayaisse, J.-B.; Lefevre, T.; Dabire, R. K.

10.1101/2020.01.27.919530 — systems biology — Posted on 2020-01-30

291 Modeling metabolic variation with single-cell expression data

Zhang, Y.; Kim, M. S.; Nguyen, E.; Taylor, D. M.

10.1101/2020.01.28.923680 — systems biology — Posted on 2020-01-30

292 Peer review and preprint policies are unclear at most major journals

Klebel, T.; Reichmann, S.; Polka, J.; McDowell, G.; Penfold, N.; Hindle, S.; Ross-Hellauer, T.

10.1101/2020.01.24.918995 — scientific communication and education — Posted on 2020-01-30

293 Targeting BDCA2 suppresses Plasmacytoid dendritic cell dependent interferon response and tissue fibrosis

Ross, R. L.; Corinaldesi, C.; Migneco, G.; Carr, I.; Antanaviciute, A.; Carriero, A.; Wasson, C.; Georgiou, I.; Distler, J. H. W.; Holmes, S.; El-Sherbiny, Y. M.; McKimmie, C. S.; Del Galdo, F.

10.1101/2020.01.30.925073 — immunology — Posted on 2020-01-30

294 Tumor control via targeting PD-L1 with chimeric antigen receptor modified NK cells

Robbins, Y.; Greene, S.; Friedman, J.; Clavijo, P. E.; Van Waes, C.; Fabian, K. P.; Padget, M. R.; Abdul Sater, H.; Lee, J. H.; Soon-Shiong, P.; Gulley, J.; Schlom, J.; Hodge, J.; Allen, C.

10.1101/2020.01.30.926535 — immunology — Posted on 2020-01-30

295 Near-atomic structures of the BBSome reveal a novel mechanism for transition zone crossing

Bahl, K.; Yang, S.; Chou, H.-T.; Woodsmith, J.; Stelzl, U.; Walz, T.; Nachury, M. V.

10.1101/2020.01.29.925610 — cell biology — Posted on 2020-01-30

296 Eating breakfast and avoiding the evening snack sustains lipid oxidation

Kelly, K. P.; McGuinness, O. P.; Buchowski, M.; Hughey, J. P.; Chen, H.; Powers, J.; Page, T.; Johnson, C. H.

10.1101/2020.01.29.923417 — animal behavior and cognition — Posted on 2020-01-30

297 Priming Is Dispensable For NLRP3 Inflammasome Activation In Human Monocytes

Gritsenko, A.; Yu, S.; Martin-Sanchez, F.; Diaz del Olmo, I.; Nichols, E.-M.; Davis, D. M.; Brough, D.; Lopez-Castejon, G.

10.1101/2020.01.30.925248 — immunology — Posted on 2020-01-30

298 Mapping of the nucleolar proteome reveals spatiotemporal organization related to intrinsic protein disorder

Stenstrom, L.; Mahdessian, D.; Gnann, C.; Leonetti, M.; Uhlen, M.; Cuylen-Haering, S.; Thul, P.; Lundberg, E.

10.1101/2020.01.30.923003 — cell biology — Posted on 2020-01-30

299 Interrogating surface versus intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates

Poc, P.; Gutzeit, V. A.; Ast, J.; Lee, J.; Jones, B.; D'Este, E.; Mathes, B.; Hodson, D.; Levitz, J.; Broichhagen, J.

10.1101/2020.01.29.924829 — physiology — Posted on 2020-01-30

300 Acute oral toxicity and risks of exposure to the neonicotinoid thiamethoxam, and other classes of systemic insecticide, for the Common Eastern Bumblebee (Bombus impatiens)

Mundy-Heisz, K. A.; Prosser, R. S.; Raine, N. E.

10.1101/2020.01.27.921510 — pharmacology and toxicology — Posted on 2020-01-30

301 Normative Circuit Dynamics Across Human Cortex During Evidence Accumulation in Changing Environments

Murphy, P. R.; Wilming, N.; Hernandez-Bocanegra, D. C.; Prat Ortega, G.; Donner, T. H.

10.1101/2020.01.29.924795 — neuroscience — Posted on 2020-01-30

302 Intention to learn modulates the impact of reward and punishment on sequence learning

Steel, A.; Baker, C. I.; Stagg, C. J.

10.1101/759639 — neuroscience — Posted on 2020-01-30

303 Single Cell Transcriptional Profiling of Phox2b-Expressing Geniculate Ganglion Neurons

Anderson, C.; Larson, E. D.

10.1101/812578 — neuroscience — Posted on 2020-01-30

304 A role for the Fem-1 gene of Drosophila melanogaster in adult courtship

Thies, M.; Berke, B.

10.1101/2020.01.19.911693 — neuroscience — Posted on 2020-01-30

305 A head-fixation system for continuous monitoring of force generated during behavior

Hughes, R.; Bakhurin, K.; Barter, J.; Zhang, J.; Yin, H.

10.1101/868703 — neuroscience — Posted on 2020-01-30

306 A peptidergic amygdala microcircuit modulates sexually dimorphic contextual fear

Rajbhandari, A. K.; Octeau, C. J.; Gonzalez, S.; Pennington, Z. T.; Trott, J.; Chavez, J.; Ngyuen, E.; Keces, N.; Hong, W.; Neve, R.; Waschek, J.; Khakh, B. S.; Fanselow, M. S.

10.1101/2020.01.28.923482 — neuroscience — Posted on 2020-01-30

307 A Systematic Nomenclature for the Drosophila Ventral Nervous System

Court, R.; Namiki, S.; Armstrong, J. D.; Borner, J.; Card, G.; Costa, M.; Dickinson, M.; Duch, C.; Korff, W.; Mann, R.; Merritt, D.; Murphey, R.; Seeds, A.; Shirangi, T.; Simpson, J.; Truman, J.; Tuthill, J.; Williams, D.; Shepherd, D.

10.1101/122952 — neuroscience — Posted on 2020-01-30

308 Acquisition of Innate Odor Preference Depends on Spontaneous and Experiential Activities During Critical Period

Qiu, Q.; Wu, Y.; Ma, L.; Ramalingam, V.; Yu, C. R.

10.1101/2020.01.28.923722 — neuroscience — Posted on 2020-01-30

309 Encoding Innately Recognized Odors via a Generalized Population Code

Qiu, Q.; Wu, Y.; Ma, L.; Yu, C. R.

10.1101/2020.01.28.923748 — neuroscience — Posted on 2020-01-30

310 Long transposon-rich centromeres in an oomycete reveal divergence of centromere features in Stramenopila-Alveolata-Rhizaria lineages

Fang, Y.; Coelho, M. A.; Shu, H.; Schotanus, K.; Thimmappa, B. C.; Yadav, V.; Chen, H.; Malc, E. P.; Wang, J.; Mieczkowski, P.; Kronmiller, B.; Tyler, B. M.; Sanyal, K.; Dong, S.; Nowrousian, M.; Heitman, J.

10.1101/765032 — microbiology — Posted on 2020-01-30

311 Increased Replication Rates of Dissimilatory Nitrogen-Reducing Bacteria Leads to Decreased Anammox Reactor Performance

Keren, R.; Lawrence, J. E.; Zhuang, W.-Q.; Jenkins, D.; Banfield, J. F.; Alvarez-Cohen, L.; Zhou, L.; Yu, K.

10.1101/534925 — microbiology — Posted on 2020-01-30

312 Family History Assessment Significantly Enhances Delivery of Precision Medicine in the Genomics Era

Bylstra, Y.; Lim, W. K.; Kam, S.; Tham, K. W.; Wu, R.; Teo, J. X.; Davila, S.; Kuan, J. L.; Chan, S. H.; Bertin, N.; Yang, C.; Rozen, S. G.; Teh, B. T.; Yeo, K. K.; Cook, S.; Orlando, L. A.; Jamuar, S. S.; Ginsburg, G.; Tan, P.

10.1101/2020.01.29.926139 — genomics — Posted on 2020-01-30

313 CRISPR Mutants of Three Y Chromosome Genes Suggest Gradual Evolution of Fertility Functions in Drosophila melanogaster

Hafezi, Y.; Sruba, S. R.; Tarrash, S. R.; Wolfner, M. F.; Clark, A. G.

10.1101/2020.01.30.926543 — genetics — Posted on 2020-01-30

314 Degrees of compositional equilibrium in tree communities vary along a gradient of temperature change rates over one decade: Application of an individual-based temporal beta diversity concept

Nakadai, R.

10.1101/2020.01.30.920660 — ecology — Posted on 2020-01-30

315 Phylogeographic analysis of Goodman's mouse lemur reveals historical interconnectivity of Madagascar's Central Highlands and eastern rainforests

Tiley, G. P.; Blanco, M. B.; Ralison, J. M.; Rasoloarison, R. M.; Stalhke, A. R.; Hohenlohe, P. A.; Yoder, A. D.

10.1101/2020.01.30.923300 — evolutionary biology — Posted on 2020-01-30

316 Human iPSC modeling elucidates mutation-specific responses to gene therapy in a genotypically diverse dominant maculopathy

10.1101/796581 — genetics — Posted on 2020-01-30

317 Pathogenic impact of transcript isoform switching in 1209 cancer samples covering 27 cancer types using an isoform-specific interaction network

Kahraman, A.; von Mering, C.

10.1101/742379 — cancer biology — Posted on 2020-01-30

318 ChiS is a noncanonical DNA-binding hybrid sensor kinase that directly regulates the chitin utilization program in Vibrio cholerae

Klancher, C. A.; Yamamoto, S.; Dalia, T. N.; Dalia, A. B.

10.1101/2020.01.10.902320 — microbiology — Posted on 2020-01-30

319 Prolonged disturbance of proteostasis induces cellular senescence via temporal mitochondrial dysfunction and enhanced mitochondrial biogenesis in human fibroblasts

Takenaka, Y.; Inoue, I.; Nakano, T.; Ikeda, M.; Kakinuma, Y.

10.1101/2020.01.22.916221 — cell biology — Posted on 2020-01-30

320 Optical measurement of voltage sensing by endogenous ion channel

Thapa, P.; Stewart, R.; Sepela, R. J.; Vivas, O.; Parajuli, L. K.; Lillya, M.; Fletcher-Taylor, S.; Cohen, B. E.; Zito, K.; Sack, J. T.

10.1101/541805 — biophysics — Posted on 2020-01-30

321 The effect of APOBEC3B deaminase on double-stranded DNA

Chapman, J. H.; Custance, M. F.; Tricola, G. M.; Shen, B.; Furano, A. V.

10.1101/750877 — biochemistry — Posted on 2020-01-30

322 An introgressed gene causes meiotic drive in Neurospora sitophila

Svedberg, J.; Vogan, A. A.; Rhoades, N. A.; Sarmarajeewa, D.; Jacobson, D. J.; Lascoux, M.; Hammond, T. M.; Johannesson, H.

10.1101/2020.01.29.923946 — evolutionary biology — Posted on 2020-01-30

323 The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer

Soldi, R.; Ghosh Halder, T.; Weston, A.; Thode, T.; Drenner, K.; Lewis, R.; Kaadige, M. R.; Srivastava, S.; Daniel Ampanattu, S.; Rodriguez del Villar, R.; Lang, J. D.; Vankayalapati, H.; Weissman, B.; Trent, J.; Hendricks, W.; Sharma, S.

10.1101/2020.01.10.902528 — cancer biology — Posted on 2020-01-30

324 Low contribution of rare species to resilience and adaptive capacity in novel spatial regimes arising from biome shifts caused by global change

Angeler, D.; Roberts, C.; Twidwell, D.; Allen, C.

10.1101/2020.01.29.924639 — ecology — Posted on 2020-01-30

325 Interpretable detection of novel human viruses from genome sequencing data

Bartoszewicz, J. M.; Seidel, A.; Renard, B. Y.

10.1101/2020.01.29.925354 — bioinformatics — Posted on 2020-01-30

326 HDAC and MAPK/ERK inhibitors cooperate to reduce viability and stemness phenotype in medulloblastoma

Jaeger, M. d. C.; Ghisleni, E. C.; Cardoso, P. S.; Siniglaglia, M.; Falcon, T.; Brunetto, A. T.; Brunetto, A. L.; de Farias, C. B.; Taylor, M. D.; Nor, C.; Ramaswamy, V.; Roesler, R.

10.1101/521393 — cancer biology — Posted on 2020-01-30

327 The consequences of variant calling decisions in secondary analyses of cancer sequencing data

Garcia-Prieto, C.; Valencia, A.; Porta-Pardo, E.

10.1101/2020.01.29.924860 — bioinformatics — Posted on 2020-01-30

328 Cerebral grey matter density is associated with neuroreceptor and neurotransporter availability: A combined PET and MRI study

Manninen, S.; Karjalainen, T.; Tuominen, L.; Hietala, J.; Kaasinen, V.; Joutsa, J.; Rinne, J.; Nummenmaa, L.

10.1101/2020.01.29.924530 — neuroscience — Posted on 2020-01-30

329 A Tug of War Between Condensate Phases in a Minimal Macromolecular System

Ghosh, A.; Zhang, X.; Zhou, H.-X.

10.1101/2020.01.29.925099 — biophysics — Posted on 2020-01-30

330 A Minimal Biophysical Model of Neocortical Pyramidal Cells: Implications for Frontal Cortex Microcircuitry and Field Potential Generation

Herrera, B.; Sajad, A.; Woodman, G. F.; Schall, J. D.; Riera, J. J.

10.1101/2020.01.29.925180 — neuroscience — Posted on 2020-01-30

331 Insights into Cross-species Evolution of Novel Human Coronavirus 2019-nCoV and Defining Immune Determinants for Vaccine Development

Ramaiah, A.; Arumugaswami, V.

10.1101/2020.01.29.925867 — microbiology — Posted on 2020-01-30

332 Neurovascular Function in a Novel Model of Experimental Atherosclerosis

Shabir, O.; Pendry, B.; Heath, P. R.; Rebollar, M. A.; Howarth, C.; Wharton, S. B.; Berwick, J.; Francis, S. E.

10.1101/2020.01.29.924936 — neuroscience — Posted on 2020-01-30

333 Distribution and localization of phosphatidylinositol 5-phosphate, 4-kinase alpha and beta in the brain

Noch, E.; Yim, I.; Milner, T.; Cantley, L.

10.1101/2020.01.29.925685 — neuroscience — Posted on 2020-01-30

334 High School Science Fair: Positive And Negative Outcomes

Grinnell, F.; Dalley, S.; Reisch, J.

10.1101/737270 — scientific communication and education — Posted on 2020-01-30

335 Sex-associated differences in cytomegalovirus prevention: Prophylactic strategy is associated with a strong kidney function impairment in female renal transplant patients

Blazquez-Navarro, A.; Dang-Heine, C.; Bauer, C.; Wittenbrink, N.; Wolk, K.; Sabat, R.; Witzke, O.; Westhoff, T. H.; Sawitzki, B.; Reinke, P.; Thomusch, O.; Hugo, C.; Babel, N.; Or-Guil, M.

10.1101/726968 — pharmacology and toxicology — Posted on 2020-01-30

336 The Developing Human Connectome Project: typical and disrupted perinatal functional connectivity

Eyre, M.; Fitzgibbon, S. P.; Ciarrusta, J.; Cordero-Grande, L.; Price, A. N.; Poppe, T.; Schuh, A.; Hughes, E.; O'Keeffe, C.; Brandon, J.; Cromb, D.; Vecchiato, K.; Andersson, J.; Duff, E. P.; Counsell, S. J.; Smith, S. M.; Rueckert, D.; Hajnal, J. V.; Arichi, T.; O'Muircheartaigh, J.; Batalle, D.; Edwards, A. D.

10.1101/2020.01.20.912881 — neuroscience — Posted on 2020-01-30

337 Implicit Learning of Temporal Behavior in Complex Dynamic Environments

Salet, J. M.; Kruijne, W.; Van Rijn, H.

10.1101/2020.01.29.924472 — neuroscience — Posted on 2020-01-30

338 Multiplexed 129Xe HyperCEST MRI detection of genetically-reconstituted bacterial protein nanoparticles in human cancer cells.

Mizushima, R.; Inoue, K.; Fujiwara, H.; Iwane, A. H.; Watanabe, T. M.; Kimura, A.

10.1101/599118 — biophysics — Posted on 2020-01-30

339 Fibroblast Growth Factor 21 (FGF21) creates sugar-specific taste aversion to fructose through action in the brain in mice.

Stevanovic, D.; Hebert, A. J.; Desai, B. N.; Singhal, G.; Adams, A. C.; Flier, J. S.; Maratos-Flier, E.

10.1101/2020.01.27.921361 — molecular biology — Posted on 2020-01-30

340 Evaluating the accuracy of a smartphone-based artificial intelligence system, PlantVillage Nuru, in identifying the viral diseases of cassava

Mrisho, L. M.; Mbilinyi, N.; Ndalahwa, M.; Ramcharan, A. M.; Kehs, A.; McCloskey, P.; Murithi, H.; Hughes, D. P.; Legg, J. P.

10.1101/2020.01.26.919449 — plant biology — Posted on 2020-01-30

341 Enduring consequences of perinatal fentanyl exposure in mice

Alipio, J. B.; Brockett, A. T.; Fox, M. E.; Tennyson, S. S.; deBettencourt, C. A.; El-Metwally, D.; Francis, N. A.; Kanold, P. O.; Lobo, M. K.; Roesch, M. R.; Keller, A.

10.1101/735464 — neuroscience — Posted on 2020-01-30

342 SynGAP splice isoforms differentially regulate synaptic plasticity and dendritic development

Araki, Y.; Hong, I.; Gamache, T. R.; Ju, S.; Collado-Torres, L.; Shin, J. H.; Huganir, R. L.

10.1101/2020.01.28.922013 — neuroscience — Posted on 2020-01-30

343 The early local and systemic Type I interferon responses to ultraviolet B light exposure are cGAS dependent.

Skopelja-Gardner, S.; An, J.; Tai, J.; Tanaka, L.; Sun, X.; Hermanson, P.; Kawasumi, M.; Green, R.; Gale, M.; Kalus, A.; Werth, V. P.; Elkon, K. B.

10.1101/835132 — immunology — Posted on 2020-01-30

344 The kinesin-8 Kip3 depolymerizes microtubules with a collective force-dependent mechanism

Bugiel, M.; Chugh, M.; Jachowski, T. J.; Schäffer, E.; Jannasch, A.

10.1101/844829 — biophysics — Posted on 2020-01-30

345 Therapeutic Drugs Targeting 2019-nCoV Main Protease by High-Throughput Screening

Li, Y.; Zhang, J.; Wang, N.; Li, H.; Shi, Y.; Guo, G.; Liu, K.; Zeng, H.; Zou, Q.

10.1101/2020.01.28.922922 — pharmacology and toxicology — Posted on 2020-01-30

346 Breaking down of healthcare system: Mathematical modelling for controlling the novel coronavirus (2019-nCoV) outbreak in Wuhan, China

Ming, W.-k.; Huang, J.; Zhang, C. J. P.

10.1101/2020.01.27.922443 — microbiology — Posted on 2020-01-30

347 Sapling: Accelerating Suffix Array Queries with Learned Data Models

Kirsche, M.; Das, A.; Schatz, M.

10.1101/2020.01.29.925768 — bioinformatics — Posted on 2020-01-30

348 TrkB induced metastatic potential of cancer by suppression of BMP mediated tumor inhibitory activity

Kim, M.; Jin, W.

10.1101/2020.01.29.924324 — cancer biology — Posted on 2020-01-30

349 Early detection of biomarkers for circulating tumor cells in Bone marrow and Peripheral blood in a fast-progressing gastric cancer model.

Bali, P.; Lozano-Pope, I.; Pachow, C.; Obonyo, M.

10.1101/2020.01.29.925727 — cancer biology — Posted on 2020-01-30

350 Evolution from adherent to suspension - systems biology of HEK293 cell line development

Malm, M.; Saghaleyni, R.; Lundqvist, M.; Giudici, M.; Chotteau, V.; Field, R.; Varley, P.; Hatton, D.; Grassi, L.; Svensson, T.; Uhlen, M.; Nielsen, J.; Rockberg, J.

10.1101/2020.01.29.924894 — systems biology — Posted on 2020-01-30

351 Cyclin E1 protein is stabilized in BRCA1 mutated breast cancers leading to synergy between CDK2 and PARP inhibitors

Aziz, D.; Portman, N.; Fernandez, K.; Lee, C.; Alexandrou, S.; Llop-Guevara, A.; Yong, A.; Wilkinson, A.; Sergio, C. M.; Ferraro, D.; Etemadmoghadam, D.; Bowtell, D.; Investigators, k.; Serra, V.; Waring, P.; Lim, E.; Caldon, C. E.

10.1101/2020.01.29.911883 — cancer biology — Posted on 2020-01-30

352 Autophagy-mediated degradation of Fatty Acid Synthase (FASN) facilitates ATRA-induced granulocytic differentiation of acute myeloid leukemia (AML) cells

Humbert, M.; Seiler, K.; Mosimann, S.; Rentsch, V.; McKenna, S. L.; Tschan, M. P.

10.1101/2020.01.29.924555 — cancer biology — Posted on 2020-01-30

353 Landscape of transcript isoforms in single T cells infiltrating in non-small cell lung cancer

Li, J.; Zhang, Z.; Ren, X.

10.1101/2020.01.29.924308 — cancer biology — Posted on 2020-01-30

354 Dynamic landscape of protein occupancy across the Escherichia coli chromosome

Freddolino, P.; Goss, T. J.; Amemiya, H. M.; Tavazoie, S.

10.1101/2020.01.29.924811 — systems biology — Posted on 2020-01-30

355 Telomere damage induces internal loops that generate telomeric circles

Mazzucco, G.; Huda, A.; Galli, M.; Piccini, D.; Giannattasio, M.; Pessina, F.; Doksani, Y.

10.1101/2020.01.29.924951 — molecular biology — Posted on 2020-01-30

356 Transposon mobilization during infection promotes drug resistance in the human fungal pathogen Cryptococcus deneoformans

Gusa, A.; Williams, J. D.; Cho, J.-E.; Floyd-Averette, A.; Sun, S.; Shouse, E. M.; Heitman, J.; Alspaugh, A.; Jinks-Robertson, S.

10.1101/2020.01.29.924845 — microbiology — Posted on 2020-01-30

357 Pervasive promoter hypermethylation of silenced TERT alleles in human cancers

Esopi, D.; Graham, M. K.; Brosnan-Cashman, J. A.; Meyers, J.; Vaghasia, A.; Gupta, A.; Kumar, B.; Haffner, M. C.; Heaphy, C. M.; De Marzo, A. M.; Meeker, A. K.; Nelson, W.; Wheelan, S. J.; Yegnasubramanian, S.

10.1101/2020.01.29.925552 — cancer biology — Posted on 2020-01-30

358 Dynamic chromatin accessibility landscape changes following interleukin-1 stimulation

Barter, M. J.; Cheung, K.; Falk, J.; Panagiotopoulos, A. C.; Cosimini, C.; O Brien, S.; Teja-Putri, K.; Neill, G.; Deehan, D. J.; Young, D. A.

10.1101/2020.01.29.924878 — genomics — Posted on 2020-01-30

359 Obesity-driven changes in ECM composition promote local invasion and metastasis of breast tumors

Wishart, A.; Peng, Y.; Conner, S.; Guarin, J.; Crews, R.; Fatherree, J.; Greenberg, A. S.; Oudin, M. J.

10.1101/2020.01.29.924431 — cancer biology — Posted on 2020-01-30

360 Deoxyribozyme-based Method for Site-specific Absolute Quantification of N6-methyladenosine Modification Fraction

Bujnowska, M.; Zhang, J.; Dai, Q.; Heideman, E. M.; Fei, J.

10.1101/2020.01.29.925255 — biochemistry — Posted on 2020-01-30

361 ATG8-interacting (ATI) 1 and 2 define a plant starvation-induced ER-phagy pathway and serve as MSBP1 (MAPR5) cargo-receptors

Wu, J.; Michaeli, S.; Galili, G.; Zehavi, H.

10.1101/2020.01.29.924886 — plant biology — Posted on 2020-01-30

362 A Systematic Evaluation of Single-cell RNA-sequencing Imputation Methods

Hou, W.; Ji, Z.; Ji, H.; Hicks, S. C.

10.1101/2020.01.29.925974 — genomics — Posted on 2020-01-30

363 A mouse tissue atlas of small non-coding RNA

Isakova, A.; Fehlmann, T.; Keller, A.; Quake, S.

10.1101/430561 — genomics — Posted on 2020-01-30

364 White matter correlates of hemi-face dominance in emotional expression

Ioannucci, S.; George, N.; FriedRich, P.; Cerliani, L.; Thiebaut de Schotten, M.

10.1101/232926 — neuroscience — Posted on 2020-01-30

365 Visualization of myosin II filament dynamics in remodeling acto-myosin networks with interferometric scattering microscopy

Mosby, L. S.; Hundt, N.; Young, G. C.; Fineberg, A.; Polin, M.; Mayor, S.; Kukura, P.; Koester, D. V.

10.1101/199778 — biophysics — Posted on 2020-01-30

366 Sperm chemotaxis is driven by the slope of the chemoattractant concentration field

Ramirez-Gomez, H. V.; Jimenez-Sabinina, V.; Velazquez-Perez, M.; Beltran, C.; Carneiro, J.; Wood, C.; Tuval, I.; Darszon, A.; Guerrero, A.

10.1101/148650 — biophysics — Posted on 2020-01-30

367 A rate threshold mechanism regulates MAPK stress signaling and survival

Johnson, A. N.; Li, G.; Jashnsaz, H.; Thiemicke, A.; Kesler, B. K.; Rogers, D. C.; Neuert, G.

10.1101/155267 — systems biology — Posted on 2020-01-30

368 WISP2/CCN5 gene knockdown in vitro and in vivo exhibits proliferation promotion of breast cancer through targeting Skp2 and p27Kip1

Lv, Y.; Zhang, C.; Li, X. J.; Gao, S.; Zheng, X.; Han, Y. Y.; Li, C.; Geng, Q.

10.1101/2020.01.29.924688 — molecular biology — Posted on 2020-01-29

369 Parental investment and immune dynamics in sex-role reversed pipefishes

Tanger, I. S.; Roth, O.

10.1101/2020.01.29.924738 — evolutionary biology — Posted on 2020-01-29

370 A simple model for glioma grading based on texture analysis applied to conventional brain MRI

Suarez-Garcia, J. G.; Hernandez-Lopez, J. M.; Moreno-Barbosa, E.; de Celis-Alonso, B.

10.1101/2020.01.29.924712 — biophysics — Posted on 2020-01-29

371 Prophylactic and therapeutic HBV vaccination by an HBs-expressing cytomegalovirus vector lacking an interferon antagonist

Huang, H.; Liu, J.; Rückborn, M.; Le-Trilling, V. T. K.; Zhu, D.; Yang, S.; Zhou, W.; Yang, X.; Feng, X.; Lu, Y.; Lu, M.; Dittmer, U.; Yang, D.; Trilling, M.

10.1101/2020.01.29.924787 — immunology — Posted on 2020-01-29

372 Effect of Altitude on Wing Metric Variation of Aedes aegypti (Diptera: Culicidae) in a Region of the Colombian Central Andes

Leyton Ramos, L. M.; Aguirre Obando, O. A.; Duque, J. E.; Garcia-Merchan, V. H.

10.1101/2020.01.29.924746 — evolutionary biology — Posted on 2020-01-29

373 An Evaluation of the Efficacy of Preclinical Models of Lung Cancer Drugs

Pan, E.; Bogumil, D.; Cortessis, V.; Yu, S.; Nieva, J.

10.1101/2020.01.29.924779 — cancer biology — Posted on 2020-01-29

374 Learning to Integrate an Artificial Sensory Device: From Decision Fusion to Sensory Integration

Nikouei Mahani, M.-A.; Bausenhart, K. M.; Ulrich, R.; Ahmadabadi, M. N.

10.1101/2020.01.29.924662 — neuroscience — Posted on 2020-01-29

375 The histone variant macroH2A1.1 regulates gene expression by direct association with their transcription start site.

Recoules, L.; Heurteau, A.; Raynal, F.; Moutahir, F.; Bejjani, F.; Jariel-Encontre, I.; Cuvier, O.; Lavigne, A.-C.; Bystricky, k.

10.1101/2020.01.29.924704 — genomics — Posted on 2020-01-29

376 Genetic diversity in global chicken breeds as a function of genetic distance to the wild populations

Malomane, D. K.; Weigend, S.; Schmitt, A. O.; Weigend, A.; Reimer, C.; Simianer, H.

10.1101/2020.01.29.924696 — genetics — Posted on 2020-01-29

377 A mathematical model of flagellar gene regulation and construction in Salmonella enterica

Keener, J.; Utsey, K.

10.1101/2020.01.29.924670 — cell biology — Posted on 2020-01-29

378 Single and binary protein electroultrafiltration using poly(vinyl-alcohol)-carbon nanotube (PVA-CNT) composite membranes

Yeung, R.; Zhu, X.; Gee, T.; Gheen, B.; Jassby, D.; Rodgers, V. G. J.

10.1101/2020.01.29.924753 — bioengineering — Posted on 2020-01-29

379 Seasonal and social factors associated with spacing in a wild territorial electric fish

Zubizarreta, L.; Quintana, L.; Hernandez, D.; Teixeira de Mello, F.; Meerhoff, M.; Massaaki Honji, R.; Guimaraes Moreira, R.; Silva, A.

10.1101/2020.01.29.924761 — animal behavior and cognition — Posted on 2020-01-29

380 eQTL Catalogue: a compendium of uniformly processed human gene expression and splicing QTLs

Kerimov, N.; Hayhurst, J. D.; Manning, J. R.; Walter, P.; Kolberg, L.; Peikova, K.; Samovica, M.; Burdett, T.; Jupp, S.; Parkinson, H.; Papatheodorou, I.; Zerbino, D. R.; Alasoo, K.

10.1101/2020.01.29.924266 — genomics — Posted on 2020-01-29

381 Neural Circuit Dynamics for Sensory Detection

Mallik, S.; Nizampatnam, S.; Nandi, A.; Saha, D.; Raman, B.; Ching, S.

10.1101/2020.01.28.923839 — systems biology — Posted on 2020-01-29

382 Gcn4 (ATF4) drives a methionine-dependent anabolic program by enabling metabolic precursor supply.

Srinivasan, R.; Walvekar, A. S.; Seshasayee, A. S. N.; Laxman, S.

10.1101/2020.01.29.924274 — systems biology — Posted on 2020-01-29

383 Phytophthora infestans Ago1-bound miRNA promotes potato late blight disease

Hu, X.; Persson Hoden, K.; Liao, Z.; Dolfors, F.; Asman, A.; Dixelius, C.

10.1101/2020.01.28.924175 — plant biology — Posted on 2020-01-29

384 Testing a convolutional neural network-based hippocampal segmentation method in a stroke population

Zavaliangos-Petropulu, A.; Tubi, M. A.; Haddad, E.; Zhu, A.; Braskie, M. N.; Jahanshad, N.; Thompson, P. M.; Liew, S.-L.

10.1101/2020.01.28.924068 — neuroscience — Posted on 2020-01-29

385 Effects of catechol-O-methyltransferase inhibition on effort-related choice behavior in male mice

DeBrosse, A.; Wheeler, A. M.; Barrow, J. C.; Carr, G. V.

10.1101/2020.01.28.924142 — neuroscience — Posted on 2020-01-29

386 Convolutional neural network MRI segmentation for fast and robust optimization of transcranial electrical current stimulation of the human brain

Sendra-Balcells, C.; Salvador, R.; Pedro, J. B.; Biagi, M. C.; Aubinet, C.; Manor, B.; Thibaut, A.; Laureys, S.; Lekadir, K.; Ruffini, G.

10.1101/2020.01.29.924985 — bioinformatics — Posted on 2020-01-29

387 Identifying spawning activity in aquatic species based on environmental DNA spikes

Tsuji, S.; Shibata, N.

10.1101/2020.01.28.924167 — molecular biology — Posted on 2020-01-29

388 Deep Sequencing Reveals Compartmentalized HIV-1 in the Semen of Men with and without STI-associated Urethritis

Council, O. D.; Zhou, S.; McCann, C. D.; Hoffman, I.; Tegha, G.; Kamwendo, D.; Matoga, M.; Kosakovsky Pond, S. L.; Cohen, M. S.; Swanstrom, R.

10.1101/2020.01.28.924225 — microbiology — Posted on 2020-01-29

389 Trimmed Constrained Mixed Effects Models: Formulations and Algorithms.

Zheng, P.; Barber, R.; Sorensen, R.; Murray, C.; Aravkin, A.

10.1101/2020.01.28.923599 — bioinformatics — Posted on 2020-01-29

390 Genetic regulation of the bacterial omega-3 polyunsaturated fatty acid biosynthesis pathway

Allemann, M. N.; Allen, E. E.

10.1101/2020.01.28.924217 — microbiology — Posted on 2020-01-29

391 Pharmaceutical-grade Rigosertib is a Microtubule-destabilizing Agent

Jost, M.; Chen, Y.; Gilbert, L. A.; Horlbeck, M. A.; Krenning, L.; Menchon, G.; Rai, A.; Cho, M. Y.; Stern, J. J.; Prota, A. E.; Kampmann, M.; Akhmanova, A.; Steinmetz, M. O.; Tanenbaum, M. E.; Weissman, J. S.

10.1101/2020.01.28.923235 — cancer biology — Posted on 2020-01-29

392 Structural analysis of Sub16 sedolisin of Trichophyton rubrum reveals a flexible nature of its pro domain

Latka, C.; Bikshapathi, J.; Aggarwal, P.; Bhavesh, N. S.; Chakraborty, R.; Khan, S. H.; Taneja, B.

10.1101/2020.01.28.922815 — biophysics — Posted on 2020-01-29

393 KALRN Mutations Promote Anti-tumor Immunity and Immunotherapy Response in Cancer

Li, M.; Ma, Y.; Zhong, Y.; Qiang, L.; Wang, X.

10.1101/2020.01.28.922682 — immunology — Posted on 2020-01-29

394 Quantifying influences on intragenomic mutation rate

Simon, H.; Huttley, G. A.

10.1101/2020.01.29.925719 — genetics — Posted on 2020-01-29

395 Expert programmers have fine-tuned cortical representations of source code

Ikutani, Y.; Kubo, T.; Nishida, S.; Hata, H.; Matsumoto, K.; Ikeda, K.; Nishimoto, S.

10.1101/2020.01.28.923953 — neuroscience — Posted on 2020-01-29

396 Information change due to natural selection in populations with and without recombination

Tiefenbrunner, W.

10.1101/2020.01.23.917724 — evolutionary biology — Posted on 2020-01-29

397 Can constraint closure provide a generalized understanding of community dynamics in ecosystems?

Peck, S. L.; Heiss, A.

10.1101/2020.01.28.924001 — ecology — Posted on 2020-01-29

398 Characterization of Escherichia coli ExbD protein modification in vivo

Kumar, A.; Postle, K.

10.1101/2020.01.29.925446 — microbiology — Posted on 2020-01-29

399 Comparative genomics reveals different population structures associated with host and geographic origin in antimicrobial-resistant Salmonella enterica

Liao, J.; Orsi, R. H.; Carroll, L. M.; Wiedmann, M.

10.1101/2020.01.28.923664 — microbiology — Posted on 2020-01-29

400 JAK Inhibitors Suppress Colon Cancer Cachexia-Associated Anorexia and Adipose Wasting in Mice

Arora, G.; Gupta, A.; Guo, T.; Gandhi, A.; Ahn, C.; Williams, D.; Iyengar, P.; Infante, R.

10.1101/2020.01.28.923391 — cancer biology — Posted on 2020-01-29

401 The Landscape of Precision Cancer Combination Therapy: A Single-Cell Perspective

Ahmadi, S.; Sukprasert, P.; Artzi, N.; Khuller, S.; Schaffer, A. A.; Ruppin, E.

10.1101/2020.01.28.923532 — bioinformatics — Posted on 2020-01-29

402 Synchronized genetic activities in Alzheimer's brains revealed by heterogeneity-capturing network analysis

Climer, S.; Templeton, A. R.; Garvin, M.; Jacobson, D.; Lane, M.; Hulver, S.; Scheid, B.; Chen, Z.; Cruchaga, C.; Zhang, W.

10.1101/2020.01.28.923730 — bioinformatics — Posted on 2020-01-29

403 Genome-wide analyses of chromatin interactions after the loss of Pol I, Pol II and Pol III

jiang, y. p.; huang, j.; lun, k. h.; li, b. y.; zheng, h. n.; li, y. j.; zhou, r.; duan, w. j.; feng, y. q.; yao, h.; li, c.; Ji, X.

10.1101/2020.01.28.923995 — genomics — Posted on 2020-01-29

404 Creative destruction: a basic computational model of cortical layer formation

Bauer, R.; Clowry, G.; Kaiser, M.

10.1101/2020.01.29.921999 — developmental biology — Posted on 2020-01-29

405 Modeling metabolic variation with single-cell expression data

Zhang, Y.; Kim, M. S.; Nguyen, E.; Taylor, D. M.

10.1101/2020.01.28.923680 — systems biology — Posted on 2020-01-29

406 Multimodal brain-age prediction and cardiovascular risk: The Whitehall II MRI sub-study

de Lange, A.-M. G.; Anatürk, M.; Kaufmann, T.; Cole, J. H.; Griffanti, L.; Zsoldos, E.; Jensen, D.; Suri, S.; Filippini, N.; Singh-Manoux, A.; Kivimäki, M.; Westlye, L. T.; Ebmeier, K. P.

10.1101/2020.01.28.923094 — neuroscience — Posted on 2020-01-29

407 Motor Learning Promotes Remyelination via New and Surviving Oligodendrocytes

Bacmeister, C. M.; Barr, H. J.; McClain, C. R.; Thornton, M. A.; Nettles, D.; Welle, C. G.; Hughes, E. G.

10.1101/2020.01.28.923656 — neuroscience — Posted on 2020-01-29

408 Encoding Innately Recognized Odors via a Generalized Population Code

Qiu, Q.; Wu, Y.; Ma, L.; Yu, C. R.

10.1101/2020.01.28.923748 — neuroscience — Posted on 2020-01-29

409 Predictive Markers of LRRK2 Inhibition in Biofluids

Wang, S.; Kelly, K.; Schussler, N.; Boularand, S.; Dubois, L.; Hsieh, F.; Tengstrand, E.; Brotchie, J. M.; Koprich, J. B.; West, A. B.

10.1101/2020.01.28.923557 — neuroscience — Posted on 2020-01-29

410 Purkinje cell neurotransmission patterns cerebellar basket cells into zonal modules that are defined by distinct pinceau sizes

Zhou, Y.; Brown, A. M.; Lackey, E. P.; Arancillo, M.; Lin, T.; Sillitoe, R. V.

10.1101/2020.01.28.923896 — neuroscience — Posted on 2020-01-29

411 A peptidergic amygdala microcircuit modulates sexually dimorphic contextual fear

Rajbhandari, A. K.; Octeau, C. J.; Gonzalez, S.; Pennington, Z. T.; Trott, J.; Chavez, J.; Ngyuen, E.; Keces, N.; Hong, W.; Neve, R.; Waschek, J.; Baljit, B. S.; Fanselow, M. S.

10.1101/2020.01.28.923482 — neuroscience — Posted on 2020-01-29

412 Acquisition of Innate Odor Preference Depends on Spontaneous and Experiential Activities During Critical Period

Qiu, Q.; Wu, Y.; Ma, L.; Yu, C. R.

10.1101/2020.01.28.923722 — neuroscience — Posted on 2020-01-29

413 Exome-wide age-of-onset analysis reveals exonic variants in ERN1, TACR3 and SPPL2C associated with Alzheimer's disease

He, L.; Loika, Y.; Park, Y.; (GTEx), G. T. E. c.; Bennett, D. A.; Kellis, M.; Kulminski, A.

10.1101/2020.01.28.923789 — neuroscience — Posted on 2020-01-29

414 Hierarchical Network Model Excitatory-Inhibitory Tone Shapes Alternative Strategies for Different Degrees of Uncertainty in Multi-Attribute Decisions

Pettine, W. W.; Louie, K.; Murray, J. D.; Wang, X.-J.

10.1101/2020.01.28.923649 — neuroscience — Posted on 2020-01-29

415 Src/FAK complex phosphorylates cardiac myosin binding protein c (cMyBP-C) in vitro and in vivo

Wang, L.; Jin, Y.; Wang, J.; Liu, Y.; Wang, R.; Zhang, S. L.; Muthuchamy, M.; Tong, C. W.; Peng, X.

10.1101/2020.01.28.923870 — molecular biology — Posted on 2020-01-29

416 Composition of the North American wood frog (Rana sylvatica) skin microbiome and seasonal variation in community structure

Douglas, A. J.; Hug, L. A.; Katzenback, B. A.

10.1101/2020.01.28.921544 — microbiology — Posted on 2020-01-29

417 Functional characterization of clinical isolates of the opportunistic fungal pathogen Aspergillus nidulans

Bastos, R. W.; Valero, C.; Silva, L. P.; Schoen, T.; Drott, M.; Brauer, V.; Silva-Rocha, R.; Lind, A.; Steenwyk, J. L.; Rokas, A.; Rodrigues, F.; Resendiz-Sharpe, A.; Lagrou, K.; Marcet-Houben, M.; Gabaldon, T.; McDonnell, E.; Reid, I.; Tsang, A.; Oakley, B. R.; Loures, F.; Almeida, F.; Huttenlocher, A.; Keller, N. P.; Ries, L.; Goldman, G. H.

10.1101/2020.01.28.917278 — microbiology — Posted on 2020-01-29

418 Delivery mode impacts newborn gut colonization efficiency

Mitchell, C.; Hogstrom, L.; Bryant, A. M.; Bergerat, A.; Cher, A.; Pochan, S.; Herman, P.; Carrigan, M.; Sharp, K.; Huttenhower, C.; Lander, E. S.; Vlamakis, H.; Xavier, R. J.; Yassour, M.

10.1101/2020.01.29.919993 — microbiology — Posted on 2020-01-29

419 Industrialization is associated with elevated rates of horizontal gene transfer in the human microbiome

Groussin, M.; Poyet, M.; Sistiaga, A.; Kearney, S. M.; Moniz, K.; Noel, M.; Hooker, J.; Gibbons, S. M.; Segurel, L.; Froment, A.; Said Mohamed, R.; Fezeu, A.; Juimo, V. A.; Girard, C.; Nguyen, L. T. T.; Shapiro, B. J.; Lehtimaki, J. M. S.; Ruokolainen, L.; Kettunen, P. P.; Vatanen, T.; Sigwazi, S.; Mabulla, A.; Dominguez-Rodrigo, M.; Summons, R. E.; Xavier, R. J.; Alm, E. J.

10.1101/2020.01.28.922104 — microbiology — Posted on 2020-01-29

420 Modifiers and Mediators of Craniosynostosis Severity Revealed by Differential Gene Expression

Dudakovic, A.; Nam, H. K.; van Wijnen, A. J.; Hatch, N. E.

10.1101/2020.01.28.923508 — developmental biology — Posted on 2020-01-29

421 Chloe: Flexible, Efficient Data Provenance and Management

Kazic, T.

10.1101/2020.01.28.923763 — bioinformatics — Posted on 2020-01-29

422 Acoustic Ejection Mass Spectrometry for High-Throughput Analysis

Zhang, H.; Liu, C.; Hua, W.; Ghislain, L. P.; Liu, J.; Aschenbrenner, L.; Noell, S.; Dirico, K.; Lanyon, L. F.; Steppan, C. M.; Arnold, D. W.; Covey, T. R.; Datwani, S. S.; Troutman, M. D.

10.1101/2020.01.28.923938 — biochemistry — Posted on 2020-01-29

423 Responsive fluorophore aggregation provides spectral contrast for fluorescence lifetime imaging

Schleyer, K. A.; Datko, B. D.; Burnside, B.; Cui, C.; Ma, X.; Grey, J. K.; Cui, L.

10.1101/2020.01.28.923672 — biochemistry — Posted on 2020-01-29

424 Extensive fragmentation and re-organization of gene co-expression patterns underlie the progression of Systemic Lupus Erythematosus

Ntasis, V. F.; Panousis, N. I.; Tektonidou, M. G.; Dermitzakis, E. T.; Boumpas, D. T.; Bertsias, G. K.; Nikolaou, C.

10.1101/2020.01.28.922559 — genomics — Posted on 2020-01-29

425 Quantitative in vivo analyses reveal a complex pharmacogenomic landscape in lung adenocarcinoma

Li, C.; Lin, W.-Y.; Rizvi, H.; Cai, H.; McFarland, C. D.; Rogers, Z. N.; Yousefi, M.; Winters, I. P.; Rudin, C. M.; Petrov, D.; Winslow, M. M.

10.1101/2020.01.28.923912 — cancer biology — Posted on 2020-01-29

426 Implications of genetic heterogeneity for plant translocation during ecological restoration

Crow, T. M.; Runcie, D. E.; Hufford, K.

10.1101/2020.01.28.923524 — ecology — Posted on 2020-01-29

427 Hilbert space filling curves for interpretable point mutation effects on peptide conformational dynamics

Rath, S. S.; Hennig, T. G.; Jorgenson, T. D.; Starkebaum, D.; Fisher-Marques, P.; Kumar, N. K.; Ustundag, B. B.; Sarikaya, M.

10.1101/2020.01.28.923961 — biophysics — Posted on 2020-01-29

428 Distinct Predictive Patterns of Antidepressant Response to Sertraline, Placebo and Bupropion using Pre-Treatment Reward Processing as examined through Functional MRI and Deep Learning: Key Results from the EMBARC Study

Nguyen, K. P.; Chin Fatt, C.; Treacher, A.; Mellema, C.; Cooper, C.; Jha, M.; Kurian, B.; Fava, M.; McGrath, P. J.; Adams, P.; Weissman, M.; Phillips, M. L.; Trivedi, M. H.; Montillo, A.

10.1101/2020.01.28.923821 — bioinformatics — Posted on 2020-01-29

429 Diverse cell stimulation kinetics identify predictive signal transduction models

Jashnsaz, H.; Fox, Z. R.; Hughes, J.; Li, G.; Munsky, B. E.; Neuert, G.

10.1101/2020.01.28.923755 — systems biology — Posted on 2020-01-29

430 Off-target glycans encountered along the synthetic biology route towards humanized N-glycans in Pichia pastoris

Laukens, B.; Jacobs, P. P.; Geysens, K.; Martins, J.; De Wachter, C.; Ameloot, P.; Morelle, W.; Haustraete, J.; Renauld, J.-C.; Samyn, B.; Contreras, R.; Devos, S.; Callewaert, N.

10.1101/2020.01.28.923631 — synthetic biology — Posted on 2020-01-29

431 A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons

Okaty, B. W.; Sturrock, N.; Escobedo Lozoya, Y.; Chang, Y.; Lyon, K. A.; Alekseyenko, O. V.; Dymecki, S. M.

10.1101/2020.01.28.923375 — neuroscience — Posted on 2020-01-29

432 Horizontal gene transfer in the human and skin commensal Malassezia: a bacterially-derived flavohemoglobin is required for NO resistance and host interaction

Ianiri, G.; Coelho, M. A.; Ruchti, F.; Sparber, F.; McMahon, T. J.; Fu, C.; Bolejack, M.; Donovan, O.; Smutney, H.; Myler, P.; Dietrich, F.; Fox, D.; LeibundGut-Landmann, S.; Heitman, J.

10.1101/2020.01.28.923367 — microbiology — Posted on 2020-01-29

433 Polarization of microbial communities between competitive and cooperative metabolism

Machado, D.; Maistrenko, O. M.; Andrejev, S.; Kim, Y.; Bork, P.; Patil, K. R.; Patil, K. R.

10.1101/2020.01.28.922583 — microbiology — Posted on 2020-01-29

434 Copy number variants outperform SNPs to reveal genotype-temperature association in a marine species

Dorant, Y.; Cayuela, H.; Wellband, K.; Laporte, M.; Rougemont, Q.; Merot, C.; Normandeau, E.; Rochette, R.; Bernatchez, L.

10.1101/2020.01.28.923490 — genomics — Posted on 2020-01-29

435 Genome-wide mapping and prediction of plant architecture in a sorghum nested association mapping population

Olatoye, M. O.; Hu, Z.; Morris, G. P.

10.1101/2020.01.28.923540 — genetics — Posted on 2020-01-29

436 StoHi-C: Using t-Distributed Stochastic Neighbor Embedding (t-SNE) to predict 3D genome structure from Hi-C Data

MacKay, K.; Kusalik, A.

10.1101/2020.01.28.923615 — bioinformatics — Posted on 2020-01-29

437 Microbiome structure of ecologically important bioeroding sponges (family Clionaidae): The role of host phylogeny and environmental plasticity.

Sacristan-Soriano, O.; Turon, X.; Hill, M.

10.1101/2020.01.28.923250 — ecology — Posted on 2020-01-29

438 A Block-Capable and Module-Extendable 4-Channel Stimulator for Acute Neurophysiology

Rapeaux, A.; Constandinou, T.

10.1101/2020.01.28.923474 — bioengineering — Posted on 2020-01-29

439 Complete Reconstitution and Deorphanization of the 3 MDa NOCAP (NOCardiosis-Associated Polyketide) Synthase

Yuet, K. P.; Liu, C. W.; Lynch, S. R.; Kuo, J.; Michaels, W.; Lee, R. B.; McShane, A. E.; Zhong, B. L.; Fischer, C. R.; Khosla, C.

10.1101/2020.01.28.923383 — biochemistry — Posted on 2020-01-29

440 FMR1 loss results in early changes to intrinsic membrane excitability in human cellular models

Susco, S. G.; Arias-Garcia, M. A.; Lopez-Huerta, V. G.; Beccard, A.; Bara, A. M.; Moffitt, J.; Korn, J.; Fu, Z.; Barrett, L. E.

10.1101/2020.01.28.923425 — neuroscience — Posted on 2020-01-29

441 Outer membrane permeabilization by the membrane attack complex sensitizes Gram-negative bacteria to antimicrobial proteins in serum and phagocytes

Heesterbeek, D. A. C.; Muts, R. M.; van Hensbergen, V. P.; de Saint Aulaire, P.; Wennekes, T.; Bardoel, B. W.; van Sorge, N. M.; Rooijakkers, S. H. M.

10.1101/2020.01.28.923243 — immunology — Posted on 2020-01-29

442 Protein evolution is structure dependent and non-homogeneous across the tree of life

Pandey, A.; Braun, E. L.

10.1101/2020.01.28.923458 — evolutionary biology — Posted on 2020-01-29

443 Turnover modulates the need for a cost of resistance in adaptive therapy

Strobl, M. A. R.; West, J.; Brown, J.; Gatenby, R.; Maini, P.; Anderson, A.

10.1101/2020.01.22.914366 — cancer biology — Posted on 2020-01-29

444 Tracking evolutionary trends towards increasing complexity: a case study in Cyanobacteria

Moya, A.; Oliver, J. L.; Verdu, M.; Delaye, L.; Arnau, V.; Bernaola-Galvan, P.; de la Fuente, R.; Diaz, W.; Gomez-Martin, C.; Gonzalez, F. M.; Latorre, A.; Lebron, R.; Roman-Roldan, R.

10.1101/2020.01.29.924464 — evolutionary biology — Posted on 2020-01-29

445 Serine Phosphorylation Regulates the P-type Potassium pump KdpFABC

Sweet, M. E.; Dubey, V. L.; Zhang, X.; Erdjument-Bromage, H.; Neubert, T. A.; Pedersen, B. P.; Khandelia, H.; Stokes, D. L.

10.1101/2020.01.28.923573 — biophysics — Posted on 2020-01-29

446 Phylogenetic signal is associated with the degree of variation in root-to-tip distances

Vankan, M.; Ho, S. Y. W.; Pardo-Diaz, C.; Duchene, D. A.

10.1101/2020.01.28.923805 — evolutionary biology — Posted on 2020-01-29

447 An empirical attack tolerance test alters the structure and species richness of plant-pollinator networks

Biella, P.; Akter, A.; Ollerton, J.; Nielsen, A.; Klecka, J.

10.1101/2020.01.28.923177 — ecology — Posted on 2020-01-29

448 Spatio-temporal Proteomic Analysis of Stress Granule disassembly using APEX Reveals Regulation by SUMOylation and links to ALS pathogenesis

Hagai, M.-K.; Siany, A.; Kedersha, N.; Knafo, N.; Rivkin, N.; Danino, Y. M.; Cohen, N.; Olender, T.; Moens, T.; Higginbottom, A.; Cooper-Knock, J.; Eitan, C.; Toth Cohen, B.; Van Den Bocho, L.; Anderson, P.; Ivanov, P.; Geiger, T.; Hornstein, E.

10.1101/2020.01.29.830133 — molecular biology — Posted on 2020-01-29

449 Sex ratio and sexual conflict in a collective action problem

Lindstedt, C.; Gerber, N.; Kokko, H.

10.1101/2020.01.29.924316 — evolutionary biology — Posted on 2020-01-29

450 Only ten percent of the global terrestrial protected area network is connected via intact land

Ward, M. S.; Saura, S.; Williams, B.; Ramirez-Delgado, J. P.; Arafeh-Dalmau, N.; Allan, J. R.; Venter, O.; Dubois, G.; Watson, J. E. M.

10.1101/2020.01.28.920488 — ecology — Posted on 2020-01-29

451 Modelling and rescue of RP2 Retinitis Pigmentosa using iPSC Derived Retinal Organoids

Lane, A.; Jovanovic, K.; Shortall, C.; Ottaviani, D.; Brugulat-Panes, A.; Palfi, A.; Chadderton, N.; Farrar, G. J.; Hardcastle, A. J.; Cheetham, M. E.

10.1101/2020.01.28.923227 — neuroscience — Posted on 2020-01-29

452 Neural stem cells traffic functional mitochondria via extracellular vesicles to correct mitochondrial dysfunction in target cells

Peruzzotti-Jametti, L.; Bernstock, J. D.; Manferrari, G.; Rogall, R.; Fernandez-Vizarra, E.; Williamson, J. C.; Braga, A.; Van den Bosch, A.; Leonardi, T.; Kittel, A.; Beninca, C.; Vicario, N.; Tan, S.; Bastos, C.; Bicci, I.; Iraci, N.; Smith, J. A.; Lehner, P. J.; Buzas, E. I.; Faria, N.; Zeviani, M.; Frezza, C.; Brisson, A.; Matheson, N. J.; Viscomi, C.; Pluchino, S.

10.1101/2020.01.29.923441 — neuroscience — Posted on 2020-01-29

453 Detecting substrate glycans of fucosyltransferases on glycoproteins with fluorescent fucose

Wu, Z. L.; Whitaker, M.; Person, A. D.; Kalabokis, V.

10.1101/2020.01.28.919860 — molecular biology — Posted on 2020-01-29

454 Integration of polygenic risk scores with modifiable risk factors improves risk prediction: results from a pan-cancer analysis

Kachuri, L.; Graff, R. E.; Smith-Byrne, K.; Meyers, T. J.; Rashkin, S. R.; Ziv, E.; Witte, J. S.; Johansson, M.

10.1101/2020.01.28.922088 — genetics — Posted on 2020-01-29

455 Parametrising diffusion-taxis equations from animal movement trajectories using step selection analysis

Potts, J. R.; Schlägel, U. E.

10.1101/2020.01.28.923052 — ecology — Posted on 2020-01-29

456 The neoantigen landscape of mycosis fungoides

Sivanand, A.; Hennessey, D.; Iyer, A.; O'Keefe, S.; Surmanowicz, P.; Vaid, G.; Gniadecki, R.

10.1101/2020.01.22.915280 — cancer biology — Posted on 2020-01-29

457 The logic of containing tumors

Viossat, Y.; Noble, R. J.

10.1101/2020.01.22.915355 — cancer biology — Posted on 2020-01-29

458 The Atlas of Inflammation-Resolution (AIR)

Serhan, C. N.; Gupta, S.; Perretti, M.; Godson, C.; Brennan, E.; Li, Y.; Soehnlein, O.; Shimizu, T.; Werz, O.; Chiurchiu, V.; Azzi, A.; Dubourdeau, M.; Smita, S.; Hoch, M.; Tripathi, A.; Cesnulevicius, K.; Lescheid, D.; Schultz, M.; Repsilber, D.; Kruse, R.; Sala, A.; Haeggstrom, J.; Levy, B. D.; Filep, J. G.; Wolkenhauer, O.

10.1101/2020.01.27.921882 — immunology — Posted on 2020-01-29

459 FCHSD2 Controls Oncogenic ERK1/2 Signaling Outcome by Regulating Endocytic Trafficking

Schmid, S. L.; Xiao, G.-Y.

10.1101/2020.01.29.924449 — cell biology — Posted on 2020-01-29

460 Mechanism of DNA surface exploration and operator bypassing during target search

Marklund, E.; van Oosten, B.; Mao, G.; Amselem, E.; Kipper, K.; Sabantsev, A.; Emmerich, A.; Globisch, D.; Zhen, X.; Lehmann, L.; Berg, O.; Johansson, M.; Elf, J.; Deindl, S.

10.1101/2020.01.29.924647 — biophysics — Posted on 2020-01-29

461 CD44 regulates blood-brain barrier integrity in response to fluid shear stress.

DeOre, B. J.; Partyka, P. P.; Fan, F.; Galie, P. A.

10.1101/2020.01.28.924043 — cell biology — Posted on 2020-01-29

462 Fragmentation of extracellular ribosomes and tRNAs shapes the extracellular RNAome

Tosar, J. P.; Segovia, M.; Gambaro, F.; Akiyama, Y.; Fagundez, P.; Costa, B.; Possi, T.; Hill, M.; Ivanov, P.; Cayota, A.

10.1101/2020.01.29.923714 — cell biology — Posted on 2020-01-29

463 Multiscale modelling of motility wave propagation in cell migration

Khataee, H.; Neufeld, Z.; Czirok, A.

10.1101/2020.01.28.924191 — biophysics — Posted on 2020-01-29

464 Bicc1 and dicer regulate left-right patterning through posttranscriptionalcontrol of the Nodal-inhibitor dand5

Maerker, M.; Getwan, M.; Dowdle, M. E.; Pelliccia, J. L.; McSheene, J. C.; Yartseva, V.; Minegishi, K.; Vick, P.; Giraldez, A.; Hamada, H.; Burdine, R. D.; Sheets, M. D.; Schweickert, A.; Blum, M.

10.1101/2020.01.29.924456 — developmental biology — Posted on 2020-01-29

465 Ultrafiltration Segregates Tissue Regenerative Stimuli Harboured Within and Independent of Extracellular Vesicles

Cooper, T. T.; Sherman, S. E.; Dayarathna, T.; Bell, G. I.; Ma, J.; McRae, D. M.; Lagugne-Labarthet, F.; Pasternak, S. H.; Lajoie, G. A.; Hess, D. A.

10.1101/2020.01.28.923037 — cell biology — Posted on 2020-01-29

466 DASC, a sensitive classifier for measuring discrete early stages in clathrin-mediated endocytosis

Wang, X.; Chen, Z.; Mettlen, M.; Noh, J.; Schmid, S. L.; Danuser, G.

10.1101/2020.01.28.924019 — cell biology — Posted on 2020-01-29

467 Peripheral Myelin Protein 22 Preferentially Partitions into Ordered Phase Membrane Domains

Marinko, J. T.; Li, G. C.; Kenworthy, A. K.; Sanders, C. R.

10.1101/2020.01.28.923771 — biophysics — Posted on 2020-01-29

468 Connecting actin polymer dynamics across multiple scales

Copos, C.; Bannish, B.; Gasior, K.; Pinals, R. L.; Rostami, M.; Dawes, A.

10.1101/2020.01.28.923698 — biophysics — Posted on 2020-01-29

469 Potential inhibitors for 2019-nCoV coronavirus M protease from clinically approved medicines

Liu, X.; Wang, X.-J.

10.1101/2020.01.29.924100 — bioinformatics — Posted on 2020-01-29

470 Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans

Martins, D.; Mazibuko, N.; Zelaya, F.; Vasilakopoulou, S.; Loveridge, J.; Oates, A.; Maltezos, S.; Mehta, M.; Howard, M.; McAlonan, G.; Murphy, D.; Williams, S.; Fotopoulou, A.; Schuschnig, U.; Paloyelis, Y.

10.1101/563056 — neuroscience — Posted on 2020-01-29

471 Therapeutic Drugs Targeting 2019-nCoV Main Protease by High-Throughput Screening

Li, Y.; Zhang, J.; Wang, N.; Li, H.; Shi, Y.; Guo, G.; Liu, K.; Zeng, H.; Zou, Q.

10.1101/2020.01.28.922922 — pharmacology and toxicology — Posted on 2020-01-29

472 Cortical morphology at birth reflects spatio-temporal patterns of gene expression in the fetal brain

Ball, G.; Seidlitz, J.; O'Muircheartaigh, J.; Dimitrova, R.; Fenchel, D.; Makropoulos, A.; Christiaens, D.; Schuh, A.; Passerat-Palmbach, J.; Cordero-Grande, L.; Hughes, E.; Price, A.; Hajnal, J. V.; Rueckert, D.; Robinson, E. C.; Edwards, D.

10.1101/2020.01.28.922849 — neuroscience — Posted on 2020-01-29

473 A workbench for the translational control of gene expression

Valleriani, A.; Chiarugi, D.

10.1101/2020.01.28.923219 — bioinformatics — Posted on 2020-01-29

474 Creld2 function during unfolded protein response is essential for liver metabolism homeostasis

Kern, P.; Balzer, N. R.; Bender, F.; Frolov, A.; Sowa, J.-P.; Bonaguro, L.; Ulas, T.; Thiele, C.; Schultze, J. L.; Canbay, A.; Bauer, R.; Mass, E.

10.1101/2020.01.28.923136 — molecular biology — Posted on 2020-01-29

475 Foveal pRF properties in the visual cortex depend on the extent of stimulated visual field

Prabhakaran, G.; Carvalho, J.; Invernizzi, A.; Kanowski, M.; Renken, R. J.; Cornelissen, F. W.; Hoffmann, M. B.

10.1101/2020.01.28.923045 — neuroscience — Posted on 2020-01-29

476 Travelling with a parasite: the evolution of resistance and dispersal syndrome during experimental range expansion

Zilio, G.; Noergaard, L. S.; Gougat-Barbera, C.; Hall, M. D.; Fronhofer, E. A.; Kaltz, O.

10.1101/2020.01.29.924498 — evolutionary biology — Posted on 2020-01-29

477 Effects of extreme hot weather on the reproductive output of great tits (Parus major, L.) in urban and natural habitats

Pipoly, I.; Preiszner, B.; Sándor, K.; Sinkovics, C.; Seress, G.; Vincze, E.; Bókony, V.; Liker, A.

10.1101/2020.01.29.924332 — ecology — Posted on 2020-01-29

478 Changing and stable chromatin accessibility supports transcriptional overhaul during neural stem cell activation

Maybury-Lewis, S. Y.; Brown, A. K.; Yeary, M.; Sloutskin, A.; Dhakal, S.; McCarthy-Sinclair, B.; Juven-Gershon, T.; Webb, A. E.

10.1101/2020.01.24.918664 — molecular biology — Posted on 2020-01-29

479 Cdc42 is required for lymphatic branching, maturation and valve formation during embryonic development

Jin, Y.; Wang, J.; Liu, Y.; Wang, R.; Chen, H.; Si, H.; Srinivasan, S.; Tharakan, B.; Zhang, S. L.; Muthuchamy, M.; Zawieja, D. C.; Peng, X.

10.1101/2020.01.28.923847 — developmental biology — Posted on 2020-01-29

480 The structures of natively assembled clathrin coated vesicles

Paraan, M.; Mendez, J. H.; Sharum, S.; Kurtin, D.; He, H.; Stagg, S. M.

10.1101/2020.01.28.923128 — biophysics — Posted on 2020-01-29

481 A pragmatic approach to make theoretical syntheses in ecology

Travassos-Britto, B.; Pardini, R.; El-Hani, C.; Prado, P. I.

10.1101/344200 — ecology — Posted on 2020-01-29

482 Oct4 regulates embryonic pluripotency via metabolic mechanisms and Stat3 signalling.

Stirparo, G. G.; Kurowski, A.; Strawbridge, S. E.; Stuart, H.; Boroviak, T. E.; Yanagida, A.; Nichols, J.

10.1101/2020.01.28.922856 — developmental biology — Posted on 2020-01-29

483 Variable environments select for short lifespan

Lind, M. I.; Ratikainen, I. I.; Andersson, J.; Carlsson, H.; Krieg, T.; Larva, T.; Maklakov, A. A.

10.1101/2020.01.29.924373 — evolutionary biology — Posted on 2020-01-29

484 Stratification of behavioral response to transcranial current stimulation by resting-state electrophysiology

Mastakouri, A. A.; Schoelkopf, B.; Grosse-Wentrup, M.

10.1101/2020.01.27.921668 — neuroscience — Posted on 2020-01-29

485 The γ-herpesviral TATA box binding protein directly interacts with RNA Polymerase II to direct late gene transcription

Castaneda, A. F.; Didychuk, A. L.; Louder, R. K.; McCollum, C. O.; Davis, Z. H.; Nogales, E.; Glaunsinger, B.

10.1101/2020.01.28.922526 — molecular biology — Posted on 2020-01-29

486 Revising CX3CR1 expression on murine classical and non-classical monocytes

Combadiere, C.; Boissonnas, A.; Meghraoui-Kheddar, A.; Barthelemy, S.

10.1101/2020.01.28.922534 — immunology — Posted on 2020-01-29

487 Virus-mediated transient expression techniques enable genetic modification of Alopecurus myosuroides

Mellado-Sanchez, M.; McDiarmid, F.; Cardoso, V.; Kanyuka, K.; MacGregor, D. R.

10.1101/2020.01.28.923466 — genetics — Posted on 2020-01-29

488 Localization of neutral evolution: selection for mutational robustnessand the maximal entropy random walk

Smerlak, M.

10.1101/2020.01.28.922831 — evolutionary biology — Posted on 2020-01-29

489 Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion

Damiano-Guercio, J.; Kurzawa, L.; Mueller, J.; Nemethova, M.; Dimchev, G.; Pokrant, T.; Bruehmann, S.; Linkner, J.; Blanchoin, L.; Sixt, M.; Rottner, K.; Faix, J.

10.1101/2020.01.27.922450 — cell biology — Posted on 2020-01-29

490 Behavioral syndromes shape evolutionary trajectories via conserved genetic architecture

Royaute, R.; Hedrick, A.; Dochtermann, N.

10.1101/619411 — genetics — Posted on 2020-01-29

491 Quantitative dissection of transcription in development yields evidence for transcription factor-driven chromatin accessibility

Eck, E.; Liu, J.; Kazemzadeh-Atoufi, M.; Ghoreishi, S.; Blythe, S. A.; Garcia, H.

10.1101/2020.01.27.922054 — biophysics — Posted on 2020-01-29

492 Brain network dynamics fingerprints are resilient to data heterogeneity

Menara, T.; Lisi, G.; Cortese, A.

10.1101/2020.01.26.920637 — neuroscience — Posted on 2020-01-29

493 Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: A data-driven analysis in the early phase of the outbreak

Zhao, S.; Lin, Q.; Ran, J.; MUSA, S. S.; Yang, G.; Wang, W.; Lou, Y.; Gao, D.; Yang, L.; He, D.; Wang, M. H.

10.1101/2020.01.23.916395 — ecology — Posted on 2020-01-29

494 Removing mains power artefacts from EEG - a novel template-based method

Zhang, S.; McCane, B.; Neo, P. S.-H.; McNaughton, N.

10.1101/2020.01.27.911586 — bioengineering — Posted on 2020-01-29

495 PathExt: a general framework for path-based mining of omics-integrated biological networks

Sambaturu, N.; Pusadkar, V.; Hannenhalli, S.; Chandra, N.

10.1101/2020.01.21.913418 — systems biology — Posted on 2020-01-29

496 Viral manipulation of functionally distinct neurons from mice to humans

Vormstein-Schneider, D. C.; Lin, J. D.; Pelkey, K. A.; Chittajallu, R.; Guo, B.; Arias Garcia, M.; Allaway, K.; Sakopoulos, S.; Schneider, G.; Stevenson, O.; Vergara, J. S.; Sharma, J.; Zhang, Q.; Franken, T. P.; Smith, J.; Ibrahim, L. A.; Mastro, K. J.; Sabri, E.; Huang, S.; Favuzzi, E.; Burbridge, T.; Xu, Q.; Guo, L.; Vogel, I.; Sanchez, V.; Saldi, G. A.; Yuan, X.; Zaghloul, K. A.; Devinsky, O.; Sabatini, B. L.; Batista-Brito, R.; Reynolds, J.; Feng, G.; Fu, Z.; McBain, C. J.; Fishell, G. J.; Dimidschstein, J.

10.1101/808170 — neuroscience — Posted on 2020-01-29

497 Multi-shanks SiNAPS Active Pixel Sensor CMOS probe: 1024 simultaneously recording channels for high-density intracortical brain mapping

Boi, F.; Perentos, N.; Lecomte, A.; Schwesig, G.; Zordan, S.; Sirota, A.; Berdondini, L.; Angotzi, G. N.

10.1101/749911 — neuroscience — Posted on 2020-01-29

498 The spatial structure of feedforward information in mouse primary visual cortex

Zhuang, J.; Larsen, R. S.; Takasaki, K. T.; Ouellette, N. D.; Daigle, T. L.; Tasic, B. T.; Waters, J.; Zeng, H.; Reid, R. C.

10.1101/2019.12.24.888156 — neuroscience — Posted on 2020-01-29

499 Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids

Dina, I.; Perez, M. J.; Panagiotakopoulou, V.; Di Napoli, G.; Brunetti, D.; Al-Shaana, R.; Kaeser, S. A.; Jucker, M.; Zeviani, M.; Viscomi, C.; Deleidi, M.

10.1101/2020.01.27.919522 — neuroscience — Posted on 2020-01-29

500 Hidden state dynamics reveals metastability across the adult lifespan

Chen, K.; Wang, Q.; Liu, D.-Q.

10.1101/2020.01.27.920652 — neuroscience — Posted on 2020-01-29

501 Insertion and deletion evolution reflects antibiotics selection pressure in a Mycobacterium tuberculosis outbreak.

Godfroid, M.; Dagan, T.; Merker, M.; Kohl, T. A.; Diel, R.; Maurer, F. P.; Niemann, S.; Kupczok, A.

10.1101/2020.01.28.922765 — microbiology — Posted on 2020-01-29

502 Evaluation of Genetic Diversity in Cultivated and Exotic Germplasm Sources of Faba Bean Using Important Morphological Traits

Kumar, P.; Kaushik, P.

10.1101/2020.01.24.918284 — genetics — Posted on 2020-01-29

503 Transcription factor enrichment analysis (TFEA): Quantifying the activity of hundreds of transcription factors from a single experiment

Rubin, J. D.; Stanley, J. T.; Sigauke, R. F.; Levandowski, C. B.; Maas, Z. L.; Westfall, J.; Taatjes, D. J.; Dowell, R. D.

10.1101/2020.01.25.919738 — bioinformatics — Posted on 2020-01-29

504 Colistin kills bacteria by targeting lipopolysaccharide in the cytoplasmic membrane

Sabnis, A.; Klockner, A.; Becce, M.; Hagart, K. L. H.; Evans, L. E.; Furniss, R. C. D.; Mavridou, D. A. I.; Larrouy-Maumus, G.; Stevens, M. M.; Edwards, A. M.

10.1101/479618 — microbiology — Posted on 2020-01-29

505 Somatic drift and rapid loss of heterozygosity suggest small effective population size of stem cells and high somatic mutation rate in asexual planaria

Asgharian, H.; Dunham, J. P.; Marjoram, P.; Nuzhdin, S. V.

10.1101/665166 — genetics — Posted on 2020-01-29

506 Modelling the emergence of whisker barrels

James, S. S.; Krubitzer, L. A.; Wilson, S. P.

10.1101/2019.12.20.884106 — developmental biology — Posted on 2020-01-29

507 Gradient in cytoplasmic pressure in the germline cells controls overlying epithelial cell morphogenesis

Lamire, L.-A.; Milani, P.; Runel, G.; Kiss, A.; Arias, L.; Vergier, B.; Das, P.; Cluet, D.; Boudaoud, A.; Grammont, M.

10.1101/440438 — developmental biology — Posted on 2020-01-29

508 Herpes zoster in HIV-1 infection: the role of CSF pleocytosis in secondary CSF escape and discordance

Hagberg, L.; Price, R. W.; Zetterberg, H.; Fuchs, D.; Gisslen, M.

10.1101/2020.01.28.922690 — neuroscience — Posted on 2020-01-28

509 Cortical ignition dynamics is tightly linked to the core organisation of the human connectome

Castro, S.; El-Deredy, W.; Battaglia, D.; Orio, P.

10.1101/2020.01.28.922708 — neuroscience — Posted on 2020-01-28

510 Trypanosomatid selenophosphate synthetase structure, function and interaction with selenocysteine lyase

da Silva, M. T. A.; Silva, I. R.; Faim, L. M.; Bellini, N. K.; Pereira, M. L.; Lima, A. L.; de Jesus, T. C. L.; Costa, F. C.; Watanabe, T. F.; Pereira, H. D.; Valentini, S. R.; Zanelli, C. F.; Borges, J. C.; Dias, M. V. B.; Chagas da Cunha, J. P.; Mittra, B.; Andrews, N. W.; Thiemann, O. H.

10.1101/2020.01.28.922716 — molecular biology — Posted on 2020-01-28

511 Structural differences between REM and non-REM dream reports assessed by graph analysis

Ribeiro, S.; Martin, J. M.; Wainstein, D.; Mota, N. B.; Mota-Rolim, S. A.; Araujo, J. F.; Solms, M.

10.1101/2020.01.28.922740 — animal behavior and cognition — Posted on 2020-01-28

512 Insertion and deletion evolution reflects antibiotics selection pressure in a Mycobacterium tuberculosis outbreak.

Godfroid, M.; Dagan, T.; Merker, M.; Kohl, T. A.; Diel, R.; Maurer, F. P.; Niemann, S.; Kupczok, A.

10.1101/2020.01.28.922765 — microbiology — Posted on 2020-01-28

513 Genetic diversity and evolution of Hantaan virus in China and its neighbors

Li, N.; Li, A.; Liu, Y.; Wu, W.; Li, C.; Yu, D.; Zhu, Y.; Li, J.; Li, D.; Wang, S.; Liang, M.

10.1101/2020.01.28.922724 — evolutionary biology — Posted on 2020-01-28

514 Vaccination with Schistosoma mansoni cholinesterases reduces parasite burden and egg viability in a mouse model of schistosomiasis

Pearson, M.; Tedla, B. A.; Pickering, D.; Becker, L.; Loukas, A.

10.1101/2020.01.28.922732 — microbiology — Posted on 2020-01-28

515 Spreading predictability in complex networks

Chen, D.-B.; Zhao, N.; Wang, J.; Yu, Y.; Zhao, J.

10.1101/2020.01.28.922757 — bioinformatics — Posted on 2020-01-28

516 Discovery of a spatially and temporally persistent core microbiome of the common bean rhizosphere

Stopnisek, N.; Shade, A.

10.1101/2020.01.20.913202 — microbiology — Posted on 2020-01-28

517 From SARS-CoV to Wuhan 2019-nCoV Outbreak: Similarity of Early Epidemic and Prediction of Future Trends

Chen, Z.; Zhang, W.; Lu, Y.; Guo, C.; Guo, Z.; Liao, C.; Zhang, X.; Zhang, Y.; Han, X.; Li, Q.; Lipkin, W. I.; Lu, J.

10.1101/2020.01.24.919241 — microbiology — Posted on 2020-01-28

518 Litterbox - A gnotobiotic zeolite-clay system to investigate Arabidopsis-microbe interactions

Miebach, M.; Schlechter, R. O.; Clemens, J.; Jameson, P. E.; Remus-Emsermann, M. N. P.

10.1101/2020.01.28.922625 — plant biology — Posted on 2020-01-28

519 A mysterious 80 nm amoeba virus with a near-complete "ORFan genome" challenges the classification of DNA viruses

Boratto, P. V. M.; Oliveira, G. P.; Machado, T. B.; Andrade, A. C. S. P.; Baudoin, J.-P.; Klose, T.; Schulz, F.; Azza, S.; Decloquement, P.; Chabriere, E.; Colson, P.; Levasseur, A.; La Scola, B.; Abrahao, J. S.

10.1101/2020.01.28.923185 — microbiology — Posted on 2020-01-28

520 A phylogenetic model for the recruitment of species into microbial communities and application to studies of thehuman microbiome

Darcy, J. L.; Washburne, A. D.; Robeson, M. S.; Prest, T.; Schmidt, S. K.; Lozupone, C. A.

10.1101/685644 — microbiology — Posted on 2020-01-28

521 Molecular characterization of a novel cytorhabdovirus with a unique genomic organization infecting yerba mate (Ilex paraguariensis) in Argentina

Bejerman, N.; Acevedo, R. M.; de Breuil, S.; Ruiz, O. A.; Sansberro, P.; Dietzgen, R. G.; Nome, C.; Debat, H. J.

10.1101/2020.01.28.923201 — microbiology — Posted on 2020-01-28

522 Transfer learning for reducing health disparities arising from data inequality

Gao, Y.; Cui, Y.

10.1101/2020.01.11.902957 — bioinformatics — Posted on 2020-01-28

523 Recent hybrids recapitulate ancient hybrid outcomes

Chaturvedi, S.; Lucas, L.; Buerkle, A.; Fordyce, J.; Forister, M.; Nice, C. C.; Gompert, Z.

10.1101/769901 — evolutionary biology — Posted on 2020-01-28

524 Epithelial morphogenesis in the perinatal mouse uterus

Vue, Z.; Behringer, R.

10.1101/2020.01.28.922385 — developmental biology — Posted on 2020-01-28

525 Transglutaminase-2 facilitates extracellular vesicle-mediated establishment of the metastatic niche

Shinde, A.; Paez, J. S.; Libring, S. M.; Hopkins, K.; Solorio, L.; Wendt, M.

10.1101/2019.12.16.875948 — cancer biology — Posted on 2020-01-28

526 Analysis of single-cell gene pair coexpression landscapes by stochastic kinetic modeling reveals gene-pair interactions in development

Gallivan, C.; Ren, H.; Read, E.

10.1101/815878 — systems biology — Posted on 2020-01-28

527 Gene Expression Signature and Molecular Mechanism of Redox Homeostasis in Colorectal Cancer

Piran, M.; Darayee, M.; Piran, M.; Sepahi, N.; Rahimi, A.

10.1101/2020.01.28.920553 — systems biology — Posted on 2020-01-28

528 Melon ethylene-mediated transcriptome and methylome dynamics provide insights to volatile production

Giovannoni, J. J.; Feder, A.; Jiao, C.; Galpaz, N.; Vrebalov, J. T.; Xu, Y.; Portnoy, V.; Tzuri, G.; Gonda, I.; Burger, J.; Gur, A.; Tadmor, Y.; Schaffer, A. A.; Lewinsohn, E.; Katzir, N.; Fei, Z.

10.1101/2020.01.28.923284 — plant biology — Posted on 2020-01-28

529 Integrated Analysis of Methylome and Transcriptome Following Developmental Atrazine Exposure in Zebrafish Reveals Aberrant Gene-Specific Methylation of Neuroendocrine and Reproductive Pathways

Bryan, C.; Lin, L.; Xie, J.; Ahkin Chin Tai, J.; Horzmann, K. A.; Wettschurack, K.; Freeman, J. L.; Zhang, M.; Yuan, C.

10.1101/2020.01.28.922179 — pharmacology and toxicology — Posted on 2020-01-28

530 SynGAP splice isoforms differentially regulate synaptic plasticity and dendritic development

Araki, Y.; Hong, I.; Gamache, T. R.; Ju, S.; Collado-Torres, L.; Shin, J. H.; Huganir, R. L.

10.1101/2020.01.28.922013 — neuroscience — Posted on 2020-01-28

531 Different forms of fear extinction are supported by distinct cortical substrates

Lay, B.; Pitaru, A. A.; Boulianne, N.; Esber, G. R.; Iordanova, M. D.

10.1101/2020.01.27.921221 — neuroscience — Posted on 2020-01-28

532 Energetics of BCM type synaptic plasticity and storing of accurate information

Karbowski, J.

10.1101/2020.01.28.922948 — neuroscience — Posted on 2020-01-28

533 Effect of acute physical exercise on motor sequence memory

Marin Bosch, B.; Bringard, A.; Logrieco, M. G.; Imobersteg, N.; Lauer, E.; Thomas, A.; Ferretti, G.; Schwartz, S.; Igloi, K.

10.1101/2020.01.28.922930 — neuroscience — Posted on 2020-01-28

534 Sonogenetics for noninvasive and cellular-level neuromodulation in rodent brain

Yang, Y.; Pacia, C. P.; Ye, D.; Zhu, L.; Baek, H.; Yue, Y.; Yuan, J.; Miller, M. J.; Cui, J.; Culver, J. P.; Bruchas, M. R.; Chen, H.

10.1101/2020.01.28.919910 — neuroscience — Posted on 2020-01-28

535 Decoding the contents of consciousness from prefrontal ensembles

Kapoor, V.; Dwarakanath, A.; Safavi, S.; Werner, J.; Besserve, M.; Panagiotaropoulos, T. I.; Logothetis, N. K.

10.1101/2020.01.28.921841 — neuroscience — Posted on 2020-01-28

536 RanBP2/Nup358 enhances miRNA activity by sumoylating and stabilizing Argonaute 1

Shen, Q.; Wang, Y. E.; Mathew, T.; Mahadevan, K.; Wu, J. Z.; Smith, H. W.; Smibert, C.; Palazzo, A. F.

10.1101/555896 — molecular biology — Posted on 2020-01-28

537 Producing Polished Prokaryotic Pangenomes with the Panaroo Pipeline

Tonkin-Hill, G.; MacAlasdair, N.; Ruis, C.; Weimann, A.; Horesh, G.; Lees, J. A.; Gladstone, R. A.; Lo, S. W.; Beaudoin, C.; Floto, R. A.; Frost, S. D. W.; Corander, J.; Bentley, S. D.; Parkhill, J.

10.1101/2020.01.28.922989 — genomics — Posted on 2020-01-28

538 Multi-tissue epigenetic analysis of the osteoarthritis susceptibility locus mapping to the plectin gene PLEC

Sorial, A. K.; Hofer, I. M.; Tselepi, M.; Cheung, K.; Parker, E.; Deehan, D. J.; Rice, S. J.; Loughlin, J.

10.1101/2020.01.28.917401 — genetics — Posted on 2020-01-28

539 AmpliconReconstructor: Integrated analysis of NGS and optical mapping resolves the complex structures of focal amplifications in cancer

Luebeck, J.; Coruh, C.; Dehkordi, S. R.; Lange, J. T.; Turner, K. M.; Deshpande, V.; Pai, D. A.; Zhang, C.; Rajkumar, U.; Law, J. A.; Mischel, P. S.; Bafna, V.

10.1101/2020.01.22.916031 — bioinformatics — Posted on 2020-01-28

540 Beware of asymptomatic transmission: Study on 2019-nCoV prevention and control measures based on extended SEIR model

Shao, P.; Shan, Y.

10.1101/2020.01.28.923169 — microbiology — Posted on 2020-01-28

541 Splice-specific deficiency of the PTSD-associated gene PAC1 leads to a paradoxical age-dependent stress behavior

Biran, J.; Gliksberg, M.; Shirat, I.; Swaminathan, A.; Levitas-Djerbi, T.; Appelbaum, L.; Levkowitz, G.

10.1101/2020.01.24.918185 — animal behavior and cognition — Posted on 2020-01-28

542 Centromere scission drives chromosome shuffling and reproductive isolation

Yadav, V.; Sun, S.; Coelho, M. A.; Heitman, J.

10.1101/809848 — genetics — Posted on 2020-01-28

543 Molecular surveillance of HIV, HBV, and HCV amongst blood donors in five Chinese regions

Lv, X.; Rodgers, M. A.; Yin, P.; Ke, L.; Fu, P.; Wu, B.; Liu, Y.

10.1101/2020.01.22.916320 — genetics — Posted on 2020-01-28

544 Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody

Tian, X.; Li, C.; Huang, A.; Xia, S.; Lu, S.; Shi, Z.; Lu, L.; Jiang, S.; Yang, Z.; Wu, Y.; Ying, T.

10.1101/2020.01.28.923011 — microbiology — Posted on 2020-01-28

545 Alterations in neuronal physiology, development, and function associated with a common duplication of chromosome 15 involving CHRNA7

Meganathan, K.; Prakasam, R.; Baldridge, D.; Gontarz, P.; Zhang, B.; Urano, F.; Bonni, A.; Constantino, J. N.; Kroll, K. L.

10.1101/2020.01.28.922187 — developmental biology — Posted on 2020-01-28

546 Cheminformatics Analysis of Natural Product Scaffolds: Comparison of Scaffolds Produced by Animals, Plants, Fungi and Bacteria

Ertl, P.; Schuhmann, T.

10.1101/2020.01.28.922955 — bioinformatics — Posted on 2020-01-28

547 Identifying Core Operons in Metagenomic Data

Hu, X.; Friedberg, I.

10.1101/2019.12.20.885269 — bioinformatics — Posted on 2020-01-28

548 An Expanded Role for WRINKLED1 Metabolic Control Based on Combined Phylogenetic and Biochemical Analyses

Kuczynski, K.; McCorkle, S.; Keereetaweep, J.; Shanklin, J.; Schwender, J.

10.1101/2020.01.28.923292 — plant biology — Posted on 2020-01-28

549 Low predictive power of clinical features for relapse prediction after antidepressant discontinuation in a naturalistic setting

Berwian, I. M.; Wenzel, J. G.; Kuehn, L.; Schnuerer, I.; Seifritz, E.; Stephan, K. E.; Walter, H.; Huys, Q. J. M.

10.1101/2020.01.28.922500 — neuroscience — Posted on 2020-01-28

550 Alzheimer's disease neuropathology, inflammation and epigenetic age: do sex and APOE matter?

Duarte-Guterman, P.; Inkster, A. M.; Albert, A. Y.; Barha, C. K.; Robinson, W.; Galea, L.

10.1101/741777 — neuroscience — Posted on 2020-01-28

551 Modelling the Replay of Dynamic Memories from Cortical Alpha Oscillations with the Sync-Fire / deSync Model.

Parish, G.; Michelmann, S.; Hanslmayr, S.; Bowman, H.

10.1101/2020.01.28.921205 — neuroscience — Posted on 2020-01-28

552 A head-fixation system for continuous monitoring of force generated during behavior

Hughes, R.; Bakhurin, K.; Barter, J.; Zhang, J.; Yin, H.

10.1101/868703 — neuroscience — Posted on 2020-01-28

553 Universal assay for measuring vertebrate telomeres by real-time quantitative PCR

Hudon, S. F.; Palencia Hurtado, E.; Beck, J. D.; Burden, S. J.; Bendixsen, D. P.; Callery, K. R.; Forbey, J. S.; Waits, L. P.; Miller, R. A.; Nielsen, O. K.; Heath, J. A.; Hayden, E. J.

10.1101/797068 — molecular biology — Posted on 2020-01-28

554 Gene regulatory effects of a large chromosomal inversion in highland maize

Crow, T. M.; Ta, J.; Nojoomi, S.; Aguilar-Rangel, M. R.; Torres Rodriguez, J. V.; Gates, D.; Rellan-Alvarez, R.; Sawers, R.; Runcie, D. E.

10.1101/861583 — genomics — Posted on 2020-01-28

555 Phenotypic delay in the evolution of bacterial antibiotic resistance: mechanistic models and their implications

Carballo-Pacheco, M.; Nicholson, M. D.; Lilja, E. E.; Allen, R. J.; Waclaw, B.

10.1101/2019.12.19.883132 — evolutionary biology — Posted on 2020-01-28

556 Efficient long fragment editing technique enables rapid construction of genetically stable bacterial strains

Huang, C.; Guo, L.; Wang, J.; Wang, N.; Huo, Y.-X.

10.1101/2020.01.28.922609 — bioengineering — Posted on 2020-01-28

557 Courtship behaviour reveals temporal regularity is a critical social cue in mouse communication

Perrodin, C.; Verzat, C.; Bendor, D.

10.1101/2020.01.28.922773 — neuroscience — Posted on 2020-01-28

558 piRNA-mediated silencing of an invading transposable element evolves rapidly through abundant de novo mutations

Zhang, S.; Kelleher, E.

10.1101/611350 — evolutionary biology — Posted on 2020-01-28

559 A unified simulation model for understanding the diversity of cancer evolution

Niida, A.; Hasegawa, T.; Innan, H.; Shibata, T.; Mimori, K.; Miyano, S.

10.1101/762997 — cancer biology — Posted on 2020-01-28

560 CloudASM: an ultra-efficient cloud-based pipeline for mapping allele-specific DNA methylation

Dumont, E. L.; Tycko, B.; Do, C.

10.1101/2020.01.28.887430 — bioinformatics — Posted on 2020-01-28

561 A metabolic network-based approach for developing feeding strategies for CHO cells to increase monoclonal antibody production

Fouladiha, H.; Marashi, S.-A.; Torkashvand, F.; Mahboudi, F.; Lewis, N. E.; Vaziri, B.

10.1101/751347 — systems biology — Posted on 2020-01-28

562 Evaluation of M2-like macrophage enrichment after diffuse traumatic brain injury through transient interleukin-4 expression from engineered mesenchymal stromal cells

Enam, S. F.; Kader, S. R.; Bodkin, N.; Lyon, J. G.; Calhoun, M.; Azrak, C.; Tiwari, P. M.; Vanover, D.; Wang, H.; Santangelo, P. J.; Bellamkonda, R. V.

10.1101/2020.01.28.918441 — neuroscience — Posted on 2020-01-28

563 Viral delivery of tissue nonspecific alkaline phosphatase diminishes craniosynostosis in one of two FGFR2C342Y/+ mouse models of Crouzon syndrome.

Nam, H. K.; Vesela, I.; Schutte, S. D.; Hatch, N.

10.1101/526400 — developmental biology — Posted on 2020-01-28

564 Mendelian randomization accounting for correlated and uncorrelated pleiotropic effects using genome-wide summary statistics.

Morrison, J.; Knoblauch, N.; Marcus, J.; Stephens, M.; He, X.

10.1101/682237 — genetics — Posted on 2020-01-28

565 Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition

Xu, W.; Cao, L.; Hao, H.

10.1101/2020.01.27.921122 — cell biology — Posted on 2020-01-28

566 Sociality and Interaction Envelope Organize Visual Action Representations

Tarhan, L.; Konkle, T.

10.1101/618272 — neuroscience — Posted on 2020-01-28

567 Neural and behavioral correlates of declarative memory are associated with temporal discounting in older adults

Lempert, K. M.; Mechanic-Hamilton, D. J.; Xie, L.; Wisse, L. E. M.; de Flores, R.; Wang, J.; Das, S. R.; Yushkevich, P. A.; Wolk, D. A.; Kable, J. W.

10.1101/720250 — neuroscience — Posted on 2020-01-28

568 Adaptive evolution among cytoplasmic piRNA proteins leads to decreased genomic auto-immunity

Wang, L.; Barbash, D.; Kelleher, E.

10.1101/521773 — evolutionary biology — Posted on 2020-01-28

569 Use of a mechanistic growth model in evaluating post-restoration habitat quality for juvenile salmonids

Polivka, C. M.; Mihaljevic, J. R.; Dwyer, G.

10.1101/665588 — ecology — Posted on 2020-01-28

570 Functional diversity metrics using kernel density n-dimensional hypervolumes

Mammola, S.; Cardoso, P.

10.1101/2020.01.25.919373 — ecology — Posted on 2020-01-28

571 Error, noise and bias in de novo transcriptome assemblies

Freedman, A. H.; Clamp, M.; Sackton, T. B.

10.1101/585745 — bioinformatics — Posted on 2020-01-28

572 Computationally-guided technology platform for on-demand production of diversified therapeutic phage cocktails

Mageeney, C. M.; Sinha, A.; Mosesso, R. A.; Medlin, D. L.; Lau, B. Y.; Rokes, A. B.; Lane, T. W.; Branda, S. S.; Williams, K. P.

10.1101/2020.01.26.918771 — microbiology — Posted on 2020-01-28

573 Comparing DNA replication programs reveals large timing shifts at centromeres of endocycling cells in maize roots

Wear, E. E.; Song, J.; Zynda, G. J.; Mickelson-Young, L.; LeBlanc, C.; Lee, T.-J.; Deppong, D. O.; Allen, G. C.; Martienssen, R. A.; Vaughn, M. W.; Hanley-Bowdoin, L.; Thompson, W. F.

10.1101/2020.01.24.917914 — genomics — Posted on 2020-01-28

574 Proteogenomic single cell analysis of skeletal muscle myocytes

Fomchenko, K. M.; Verma, R. X.; Kannan, S.; Lin, B. L.; Yang, X.; Nieuwenhuis, T. O.; Patil, A. H.; Fox-Talbot, K.; McCall, M. N.; Kwon, C.; Kass, D. A.; Rosenberg, A. Z.; Halushka, M. K.

10.1101/2020.01.23.916791 — genomics — Posted on 2020-01-28

575 Adaptation to contrasting habitats underlies distinct plastic responses to environmental variation in two closely related Senecio species

Walter, G. M.; Clark, J.; Cristaudo, A.; Nevado, B.; Catara, S.; Paunov, M.; Velikova, V.; Filatov, D.; Cozzolino, S.; Hiscock, S.; Bridle, J. R.

10.1101/2020.01.24.918201 — evolutionary biology — Posted on 2020-01-28

576 Morphological and molecular evidence for range extension and first occurrence of the Japanese seahorse, Hippocampus mohnikei (Bleeker 1853) in a bay-estuarine system of Goa, central west coast of India

Sanaye, S. V.; Khandeparker, R. D.; Rayadurga, A. S.; Shivaram, M. S.; Kankonkar, H.; Narvekar, J.; Gaunthankar, M.

10.1101/705814 — ecology — Posted on 2020-01-28

577 Vernalization alters sugar beet (Beta vulgaris) sink and source identities and reverses phloem translocation from taproots to shoots

Martins Rodrigues, C.; Müdsam, C.; Keller, I.; Zierer, W.; Czarnecki, O.; Corral, J. M.; Reinhardt, F.; Nieberl, P.; Sommer, F.; Schroda, M.; Mühlhaus, T.; Harms, K.; Flügge, U.-I.; Koch, W.; Ludewig, F.; Neuhaus, H. E.; Pommerrenig, B.

10.1101/2020.01.28.922906 — plant biology — Posted on 2020-01-28

578 Reliability Assessment of Tissue Classification Algorithms for Multi-Center and Multi-Scanner Data

Dadar, M.; Duchesne, S.

10.1101/2020.01.28.922971 — neuroscience — Posted on 2020-01-28

579 Rethinking the role of lipids in lager yeast cell during beer fermentation from a transcriptome and systems biology perspective

Bonatto, D.

10.1101/2020.01.28.922898 — microbiology — Posted on 2020-01-28

580 Nuclear localization of calcium-activated BK channels in skate ampullary electroreceptors

Chen, A. L.; Wu, T. H.; Shi, L.; Clusin, W. T.; Kao, P. N.

10.1101/2020.01.27.922161 — neuroscience — Posted on 2020-01-28

581 MAPK-induced miR-29 restrains melanoma progression by targeting MAFG

Vera, O.; Bok, I.; Jasani, N.; Nakamura, K.; Xu, X.; Mecozzi, N.; Karreth, F. A.

10.1101/2020.01.27.922153 — cancer biology — Posted on 2020-01-28

582 Symmetry structures in dynamic models of biochemical systems

Ohlsson, F.; Borgqvist, J.; Cvijovic, M.

10.1101/2020.01.27.922005 — systems biology — Posted on 2020-01-28

583 Projections between visual cortex and pulvinar nucleus in the rat

Scholl, L. R.; Foik, A. T.; Lyon, D. C.

10.1101/2020.01.27.921858 — neuroscience — Posted on 2020-01-28

584 A mutant RNA polymerase activates the general stress response, enabling E. coli adaptation to late prolonged stationary phase

Nandy, P.; Chib, S.; Seshasayee, A. S. N.

10.1101/2020.01.27.922484 — microbiology — Posted on 2020-01-28

585 Transcriptomic Organization of Human Posttraumatic Stress Disorder

Girgenti, M. J.; Wang, J.; Ji, D.; Cruz, D.; Traumatic Stress Brain Research Study Group, ; The Million Veteran Program, ; Stein, M. B.; Gelernter, J.; Young, K. A.; Huber, B. R.; Williamson, D. E.; Friedman, M. J.; Krystal, J. H.; Zhao, H.-y.; Duman, R. S.

10.1101/2020.01.27.921403 — genomics — Posted on 2020-01-28

586 Variability in gene expression is associated with incomplete penetrance in inherited eye disorders

Green, D. J.; Sallah, S. R.; Ellingford, J. M.; Lovell, S. C.; Sergouniotis, P. I.

10.1101/2020.01.28.915504 — genetics — Posted on 2020-01-28

587 Assortative mating, sexual selection and their consequences for gene flow in Littorina

Perini, S.; Rafajlovic, M.; Westram, A. M.; Johannesson, K.; Butlin, R. K.

10.1101/2020.01.28.922658 — evolutionary biology — Posted on 2020-01-28

588 Quantitative dissection of transcription in development yields evidence for transcription factor-driven chromatin accessibility

Eck, E.; Liu, J.; Kazemzadeh-Atoufi, M.; Ghoreishi, S.; Blythe, S. A.; Garcia, H.

10.1101/2020.01.27.922054 — biophysics — Posted on 2020-01-28

589 DeepTE: a computational method for de novo classification of transposons with convolu-tional neural network

Yan, H.; Bombarely, A.; Li, S.

10.1101/2020.01.27.921874 — bioinformatics — Posted on 2020-01-28

590 The roles of aridification and sea level changes in the diversification and persistence of freshwater fish lineages

Buckley, S. J.; Brauer, C.; Unmack, P.; Hammer, M.; Beheregaray, L. B.

10.1101/2020.01.27.922427 — evolutionary biology — Posted on 2020-01-28

591 Brain size predicts learning abilities in bees

Collado, M. A.; Marin Montaner, C.; Molina, F. P.; Sol, D.; Bartomeus, I.

10.1101/2020.01.27.921114 — animal behavior and cognition — Posted on 2020-01-28

592 Constitutive Steroidal Glycoalkaloid Biosynthesis in Tomato is Regulated by the Clade IIIe Basic Helix-Loop-Helix Transcription Factors MYC1 and MYC2

Goossens, A.; Pauwels, L.; Ron, M.; Fernandez-Calvo, P.; Vanden Bossche, R.; De Clercq, R.; Ceulemans, E.; Molina-Hidalgo, F. J.; Pollier, J.; De Meyer, M.; Swinnen, G.

10.1101/2020.01.27.921833 — plant biology — Posted on 2020-01-28

593 Between-subject prediction reveals a shared representational geometry in the rodent hippocampus

Chen, H.-T.; Manning, J. R.; van der Meer, M. A.

10.1101/2020.01.27.922062 — neuroscience — Posted on 2020-01-28

594 Negative Overgeneralization is Associated with Pattern Completion in Peripubertal Youth

McMakin, D. L.; Kimbler, A.; Tustison, N. J.; Pettit, J. W.; Mattfeld, A. T.

10.1101/2020.01.27.921742 — neuroscience — Posted on 2020-01-28

595 Fibroblast Growth Factor 21 (FGF21) creates sugar-specific taste aversion to fructose through action in the brain in mice.

Stevanovic, D.; Hebert, A. J.; Desai, B. N.; Singhal, G.; Adams, A. C.; Flier, J. S.; Maratos-Flier, E.

10.1101/2020.01.27.921361 — molecular biology — Posted on 2020-01-28

596 Quantitative assessment of morphology and sub-cellular changes in macrophages and trophoblasts during inflammation

SINGH, R.; DUBEY, V.; WOLFSON, D.; AHMAD, A.; ACHARYA, G.; AHMAD, A.; MEHTA, D. S.; BASNET, P.; Ahluwalia, B. S.

10.1101/2020.01.27.921908 — cell biology — Posted on 2020-01-28

597 Most commonly mutated genes in High Grade Serous Ovarian Carcinoma are nonessential for ovarian surface epithelial stem cell transformation

Yamulla, R. J.; Nalubola, S.; Flesken-Nikitin, A.; Nikitin, A. C.; Schimenti, J. C.

10.1101/2020.01.27.921718 — cancer biology — Posted on 2020-01-28

598 The Prorenin Receptor and its Soluble Form Contribute to Lipid Homeostasis

Gatineau, E.; Arthur, G.; Poupeau, A.; Nichols, K. M.; Spear, B. T.; Graf, G.; Temel, R. E.; Yiannikouris, F.

10.1101/2020.01.27.922138 — physiology — Posted on 2020-01-28

599 Sex dependent compensatory mechanisms to preserve blood pressure homeostasis in PGI2 receptor deficient mice

Tang, S. Y.; Anderson, S. T.; Meng, H.; Sarantopoulou, D.; Ricciotti, E.; Hennessy, E. J.; Grant, G. R.; FitzGerald, G. A.

10.1101/2020.01.27.921791 — pharmacology and toxicology — Posted on 2020-01-28

600 The role of humans on Antillean land vertebrate extinctions: new insights from Cuba

Orihuela, J.; Vinola, L. W.; Jimenez Vazquez, O.; Mychajliw, A.; Hernandez de Lara, O.; Lorenzo, L.; Soto-Centeno, J. A.

10.1101/2020.01.27.922237 — paleontology — Posted on 2020-01-28

601 HySyn: A genetically-encoded synthetic synapse to rewire neural circuits in vivo

Hawk, J. D.; Colon-Ramos, D.

10.1101/2020.01.27.922203 — neuroscience — Posted on 2020-01-28

602 Chronic hM3Dq signaling in microglia ameliorates neuroinflammation in male mice

Binning, W.; Hogan-Cann, A. E.; Sakae, D. Y.; Maksoud, M.; Ostapchenko, V.; Al-Onaizi, M.; Matovic, S.; Lu, W.-Y.; Prado, M. A. M.; Inoue, W.; Prado, V. F.

10.1101/2020.01.27.921809 — neuroscience — Posted on 2020-01-28

603 The Efficiency, Efficacy, and Retention of Motor Training in Chronic Stroke

Wang, C.; Winstein, C. J.; D'Argenio, D. Z.; Schweighofer, N.

10.1101/2020.01.27.922096 — neuroscience — Posted on 2020-01-28

604 Evaluation of DNA extraction protocols from liquid-based cytology specimens for studying cervical microbiota

Shibata, T.; Nakagawa, M.; Coleman, H. N.; Owens, S. M.; Greenfield, W. W.; Sasagawa, T.; Robeson, M. S.

10.1101/2020.01.27.921619 — microbiology — Posted on 2020-01-28

605 A variant in SMOC2, inhibiting BMP signaling by competitively binding to BMPR1B, causes multiple epiphyseal dysplasia

Long, F.; Li, L.; Shi, H.; Li, P.; Guo, S.; Ma, Y.; Li, Y.; Wei, S.; Gao, F.; Gao, S.; Wang, M.; Duan, R.; Wang, X.; Yang, K.; Liu, A.; Wang, A.; Chen, X.; Sun, W.; Li, X.; Li, J.; Liu, Q.

10.1101/2020.01.27.921825 — genomics — Posted on 2020-01-28

606 Anopheles gambiae maternal age and parous state control offspring susceptibility to Plasmodium falciparum

Mitri, C.; Isabelle, T.; Lecoq, M.-T.; Thouvenot, C.; Touron, S.; Landier, A.; Bischoff, E.; Bourgouin, C.

10.1101/2020.01.27.922070 — genetics — Posted on 2020-01-28

607 Physical-biological interaction underlying phylogeographic pattern of coral-dependent fishes around the Arabian Peninsula

Torquato, F. d. O.

10.1101/2020.01.27.921411 — ecology — Posted on 2020-01-28

608 A paralog-specific role of the COPI pathway in the neuronal differentiation of murine pluripotent cells

Goyal, M.; Zhao, X.; Bozhinova, M.; Andrade-Lopez, K. L.; de Heus, C.; Schulze-Dramac, S.; Mueller-McNicoll, M.; Klumperman, J.; Bethune, J.

10.1101/2020.01.27.921924 — cell biology — Posted on 2020-01-28

609 HASLR: Fast Hybrid Assembly of Long Reads

Haghshenas, E.; Asghari, H.; Stoye, J.; Chauve, C.; Hach, F.

10.1101/2020.01.27.921817 — bioinformatics — Posted on 2020-01-28

610 Survival of environmental DNA in natural environments: Surface charge and topography of minerals as driver for DNA storage

Freeman, C. L.; Dieudonne, L.; Collins, M. J.; Sand, K. K.

10.1101/2020.01.28.922997 — biochemistry — Posted on 2020-01-28

611 A derivation error exists in the current implementation of the Johnson et al. (1942) modified Arrhenius function that affects leaf carbon balance models

Murphy, B. K.; Stinziano, J. R.

10.1101/2020.01.27.921973 — plant biology — Posted on 2020-01-28

612 Curcumin Analogues as the Inhibitors of TLR4 Pathway in Inflammation and Their Drug Like Potentialities: A Computer-based Study

Ullah, M. A.; Johora, F. T.; Sarkar, B.; Araf, Y.; Rahman, M. H.

10.1101/2020.01.27.921528 — pharmacology and toxicology — Posted on 2020-01-28

613 Behavioral recovery after a spinal deafferentation injury in monkeys does not correlate with corticospinal sprouting

Crowley, M.; Lilak, A.; Garner, J.; Darian-Smith, C. J.

10.1101/2020.01.27.921957 — neuroscience — Posted on 2020-01-28

614 Implantation technique, safety and complications of robot-assisted stereoelectroencephalography exploration of the limbic thalamus in human focal epilepsy

Chaitanya, G.; Romeo, A.; Ilyas, A.; Irannejad, A.; Toth, E.; Elsayed, G.; Bentley, N.; Riley, K. O.; Pati, S.

10.1101/2020.01.27.922195 — neuroscience — Posted on 2020-01-28

615 Sulcal depth in medial ventral temporal cortex predicts the location of a place-selective region in macaques, children, and adults.

Natu, V. S.; Arcaro, M.; Barnett, M. A.; Gomez, J.; Livingstone, M.; Grill-Spector, K.; Weiner, K. S.

10.1101/2020.01.27.921346 — neuroscience — Posted on 2020-01-28

616 Architecture of the AP2:clathrin coat on the membranes of clathrin-coated vesicles

Kovtun, O.; Kane Dickson, V.; Kelly, B. T.; Owen, D. J.; Briggs, J. A. G.

10.1101/2020.01.28.922591 — molecular biology — Posted on 2020-01-28

617 Dynamics of replication origin over-activation

Fu, H.; Redon, C. E.; Utani, K.; Thakur, B.; Jang, S.; Marks, A. B.; Zhuang, S.; Lazar, S. B.; Rao, M.; Mencer, S.; Gross, J. M.; Pongor, L.; Aladjem, M. I.

10.1101/2020.01.27.922211 — genomics — Posted on 2020-01-28

618 The effect of drug dose and timing of treatment on the emergence of drug resistance in vivo in a malaria model

Acosta, M. M.; Sim, D.; Bram, J. T.; Read, A. F.

10.1101/2020.01.27.921940 — evolutionary biology — Posted on 2020-01-28

619 Warming-enhanced priority effects at population and community levels in aquatic bacteria

Vass, M.; Szekely, A. J.; Lindström, E. S.; Osman, O. A.; Langenheder, S.

10.1101/2020.01.27.921726 — ecology — Posted on 2020-01-28

620 Injectable therapeutic organoids using sacrificial hydrogels

Rossen, N. S.; Anandakumaran, P. N.; zur Nieden, R.; Lo, K.; Luo, W.; Park, C.; Huyan, C.; Fu, Q.; Song, Z.; Singh-Moon, R. P.; Chung, J.; Goldenberg, J.; Sampat, N.; Harimoto, T.; Bajakian, D.; Gillette, B. M.; Sia, S. K.

10.1101/2020.01.27.922112 — bioengineering — Posted on 2020-01-28

621 Theoretical Design of Paradoxical Signaling-Based Synthetic Population Control Circuit in E. coli

Mayalu, M. N.; Murray, R. M.

10.1101/2020.01.27.921734 — systems biology — Posted on 2020-01-28

622 Simultaneous stimulation of RuBP regeneration and electron transport increases productivity and water use efficiency under field conditions

Lopez-Calcagno, P. E.; Brown, K. L.; Simkin, A. J.; Fisk, S. J.; Lawson, T.; Raines, C. A.

10.1101/2020.01.27.920843 — plant biology — Posted on 2020-01-28

623 A ballistic pollen dispersal strategy hidden in stylar oscillation

Ito, S.; Rajabi, H.; Gorb, S. N.

10.1101/2020.01.27.920710 — plant biology — Posted on 2020-01-28

624 Acute oral toxicity and risks of exposure to the neonicotinoid thiamethoxam, and other classes of systemic insecticide, for the Common Eastern Bumblebee (Bombus impatiens)

Mundy-Heisz, K. A.; Prosser, R. S.; Raine, N. E.

10.1101/2020.01.27.921510 — pharmacology and toxicology — Posted on 2020-01-28

625 Testing of the survivin suppressant YM155 in a large panel of drug-resistant neuroblastoma cell lines

Michaelis, M.; Voges, Y.; Rothweiler, F.; Weipert, F.; Zhia-Amad, A.; Cinatl, J.; von Deimling, A.; Westermann, F.; Roedel, F.; Wass, M. N.; Cinatl, J.

10.1101/2020.01.27.921312 — pharmacology and toxicology — Posted on 2020-01-28

626 Nelfinavir was predicted to be a potential inhibitor of 2019 nCov main protease by an integrative approach combining homology modelling, molecular docking and binding free energy calculation

Xu, Z.; Peng, C.; Shi, Y.; Zhu, Z.; Mu, K.; Wang, X.; Zhu, W.

10.1101/2020.01.27.921627 — pharmacology and toxicology — Posted on 2020-01-28

627 Abnormal center of mass control during balance is associated with falls in Parkinson's disease

McKay, J. L.; Lang, K. C.; Bong, S.; Hackney, M. E.; Factor, S. A.; Ting, L. H.

10.1101/2020.01.27.921379 — neuroscience — Posted on 2020-01-28

628 Layer-specific inhibitory microcircuits of layer 6 interneurons in rat prefrontal cortex

Ding, C.; Emmenegger, V.; Schaffrath, K.; Feldmeyer, D.

10.1101/2020.01.27.920686 — neuroscience — Posted on 2020-01-28

629 A unified computational model for cortical post-synaptic plasticity

Mäki-Marttunen, T.; Iannella, N.; Edwards, A. G.; Einevoll, G.; Blackwell, K. T.

10.1101/2020.01.27.921254 — neuroscience — Posted on 2020-01-28

630 The brain's hedonic valuation system's resting-state connectivity predicts weight loss and correlates with leptin

Schmidt, L.; Medarwar, E.; Aron-Wisnewsky, J.; Ganser, L.; Poitou, C.; Clement, K.; Plassmann, H.

10.1101/2020.01.27.921098 — neuroscience — Posted on 2020-01-28

631 Layer and rhythm specificity for predictive routing

Bastos, A.; Lundqvist, M.; Waite, A.; Kopell, N.; Miller, E. K.

10.1101/2020.01.27.921783 — neuroscience — Posted on 2020-01-28

632 Different forms of fear extinction are supported by distinct cortical substrates

Iordanova, M. D.; Lay, B.; Pitaru, A. A.; Boulianne, N.; Esber, G. R.

10.1101/2020.01.27.921221 — neuroscience — Posted on 2020-01-28

633 Object-based analyses in FIJI/ImageJ to measure local RNA translation sites in neurites in response to Aβ1-42 oligomers

Gamarra, M.; Blanco-Urrejola, M.; Batista, A. F. R.; Imaz, J.; Baleriola, J.

10.1101/2020.01.27.921494 — neuroscience — Posted on 2020-01-28

634 Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization

Dominguez-Meijide, A.; Vasili, E.; Koenig, A.; Cima-Omori, M.-S.; Leonov, A.; Ryazanov, S.; Giese, A.; Zweckstetter, M.; Griesinger, C.; Outeiro, T. F.

10.1101/2020.01.27.921643 — neuroscience — Posted on 2020-01-28

635 Mapping physiological ADP-ribosylation using Activated Ion Electron Transfer Dissociation (AI-ETD)

Buch-Larsen, S. C.; Hendriks, I. A.; Lodge, J. M.; Rykaer, M.; Furtwangler, B.; Shishkova, E.; Westphall, M. S.; Coon, J. J.; Nielsen, M. L.

10.1101/2020.01.27.921650 — molecular biology — Posted on 2020-01-28

636 Antigenic variation by switching inter-chromosomal interactions with an RNA splicing locus in trypanosomes

Faria, J.; Luzak, V.; Mueller, L. S. M.; Brink, B. G.; Hutchinson, S.; Glover, L.; Horn, D.; Siegel, T. N.

10.1101/2020.01.27.921452 — molecular biology — Posted on 2020-01-28

637 Integrin β3, a RACK1 interacting protein, is required for porcine reproductive and respiratory syndrome virus infection and NF-κB activation in Marc-145 cells

Yang, C.; Lan, R.; Wang, X.; Zhao, ; Li, X.; Bi, J.; Wang, J.; Yang, G.; Lin, Y.; Liu, J.; Yin, G.

10.1101/2020.01.27.922476 — microbiology — Posted on 2020-01-28

638 Polymorphisms in immunoglobulin heavy chain variable genes and their upstream regions

Mikocziova, I.; Gidoni, M.; Lindeman, I.; Peres, A.; Snir, O.; Yaari, G.; Sollid, L. M.

10.1101/2020.01.27.921197 — immunology — Posted on 2020-01-28

639 Molecular and cellular heterogeneity of gastric cancer explained by methylation-driven key regulators

Yoo, S.; Chen, Q.; Wang, L.; Wang, W.; Chakravarthy, A.; Busuttil, R. A.; Boussioutas, A.; Liu, D.; She, J.; Fenton, T. R.; Zhang, J.; Fan, X.; Leung, S. y.; Zhu, J.

10.1101/2020.01.27.920744 — genomics — Posted on 2020-01-28

640 Protective Population Behavior Change in Outbreaks of Emerging Infectious Disease

Lodge, E. K.; Schatz, A. M.; Drake, J. M.

10.1101/2020.01.27.921536 — ecology — Posted on 2020-01-28

641 Proteome allocation influences population dynamics in microbial communities

Pacciani-Mori, L.; Giometto, A.; Suweis, S.; Maritan, A.

10.1101/2020.01.27.921478 — biophysics — Posted on 2020-01-28

642 Precise mapping of new group I introns in tRNA genes

Williams, K. P.

10.1101/2020.01.27.920355 — genomics — Posted on 2020-01-28

643 Prior selection prevents the loss of an ecosystem cycle during acidification

van Moorsel, S. J.; Marleau, J.; Negrin Dastis, J. O.; Bazerghi, C.; Fugere, V.; Petchey, O. L.; Gonzalez, A.

10.1101/2020.01.27.921437 — ecology — Posted on 2020-01-28

644 Di-arginine and FFAT-like motifs retain a subpopulation of PRA1 at ER-mitochondria membrane contact sites

Abu Irqeba, A.; Ogilvie, J. M.

10.1101/2020.01.27.922260 — cell biology — Posted on 2020-01-28

645 Fine-tuning biosensor dynamic range based on rational design of cross-ribosome-binding sites in bacteria

Ding, N.; Zhou, S.; Yuan, Z.; Zhang, X.; Chen, J.; Deng, Y.

10.1101/2020.01.27.922302 — bioinformatics — Posted on 2020-01-28

646 The Role of Spatial Separation on Selective and Distributed Attention to Speech

Pinto, D.; Agmon, G.; Zion Golumbic, E.

10.1101/2020.01.27.920785 — neuroscience — Posted on 2020-01-28

647 Neural correlates of winning and losing fights in poison frog tadpoles

Fischer, E. K.; Alvarez, H.; Lagerstrom, K. M.; Petrillo, R.; Ellis, G.; O'Connell, L. A.

10.1101/2020.01.27.922286 — neuroscience — Posted on 2020-01-28

648 A novel metabarcoding strategy for studying nematode communities

Sikder, M. M.; Vestergard, M.; Sapkota, R.; Kyndt, T.; Nicolaisen, M.

10.1101/2020.01.27.921304 — ecology — Posted on 2020-01-28

649 Matrix Stiffness Regulates Liver Sinusoidal Endothelial Cell Function Mimicking Responses in Fatty Liver Disease

Natarajan, V.; Moeller, M.; Casey, C.; Harris, E.; Kidambi, S.

10.1101/2020.01.27.921353 — bioengineering — Posted on 2020-01-28

650 A Dual Reward-Place Association Task to Study the Preferential Retention of relevant Memories in Rats

Michon, F.; Sun, J.-J.; Kim, C. Y.; Kloosterman, F.

10.1101/2020.01.27.921593 — animal behavior and cognition — Posted on 2020-01-28

651 Xenobiotic compounds modulate cytotoxicity of Aβ amyloids and interact with neuroprotective chaperone L-PGDS

Low, K. J. Y.; Phillips, M.; Pervushin, K.

10.1101/2020.01.27.920884 — neuroscience — Posted on 2020-01-28

652 Environmental biases in the study of ecological networks at the planetary scale

Poisot, T.; Bergeron, G.; Cazelles, K.; Dallas, T.; Gravel, D.; MacDonald, A.; Mercier, B.; Vissault, S.

10.1101/2020.01.27.921429 — ecology — Posted on 2020-01-28

653 MazeMaster: an open-source Python-based software package for controlling virtual reality experiments

Bexter, A.; Kampa, B. M.

10.1101/2020.01.27.921148 — neuroscience — Posted on 2020-01-28

654 Chromatin features define adaptive genomic regions in a fungal plant pathogen

Cook, D. E.; Kramer, M. H.; Seidl, M. F.; Thomma, B. P.

10.1101/2020.01.27.921486 — genomics — Posted on 2020-01-28

655 An analysis of Species Conservation Action Plans in Guinea

Couch, C.; Molmou, D.; Magassouba, S.; Doumbouya, S.; Diawara, M.; Diallo, M. Y.; Keita, S. M.; Kone, F.; Diallo, M. C.; Kourouma, S.; Diallo, M. B.; Keita, M. S.; Oulare, A.; Darbyshire, I.; Nic Lughadha, E.; van der Burgt, X.; Larridon, I.; Cheek, M.

10.1101/2020.01.27.920751 — ecology — Posted on 2020-01-28

656 PathWalks: Identifying pathway communities using a disease-related map of integrated information

Karatzas, E.; Zachariou, M.; Bourdakou, M.; Minadakis, G.; Oulas, A.; Kolios, G.; Delis, A.; Spyrou, G.

10.1101/2020.01.27.921270 — bioinformatics — Posted on 2020-01-28

657 Tailored polymeric, photovoltaic, and near-infrared-responsive neuroprosthesis

Airaghi Leccardi, M. J.; Chenais, N. A.; Ferlauto, L.; Kawecki, M.; Zollinger, E. G.; Ghezzi, D.

10.1101/2020.01.27.920819 — bioengineering — Posted on 2020-01-28

658 Hidden state dynamics reveals metastability across the adult lifespan

Chen, K.; Wang, Q.; Liu, D.-Q.

10.1101/2020.01.27.920652 — neuroscience — Posted on 2020-01-28

659 Irrelevant Predictions: Distractor Rhythmicity Modulates Neural Encoding in Auditory Cortex

Makiv, S.; Zion Golumbic, E.

10.1101/2020.01.27.920728 — neuroscience — Posted on 2020-01-28

660 A cell atlas of human thymic development defines T cell repertoire formation

Park, J.-E.; Botting, R. A.; Dominguez Conde, C.; Popescu, D.-M.; Lavaert, M.; Kunz, D. J.; Stephenson, E.; Ragazzini, R.; Tuck, E.; Wilbrey-Clark, A. L.; Ferdinand, J. R.; Webb, S.; Maunder, D.; Vandamme, N.; Mahbubani, K. T.; Polanski, K.; Mamanova, L.; Fuller, A.; Filby, A.; Reynolds, G.; Dixon, D.; Saeb-Parsy, K.; Lisgo, S.; Henderson, D.; Vento-Tormo, R.; Meyer, K. B.; Saeys, Y.; Bonfanti, P.; Behjati, S.; Clatworthy, M. R.; Taghon, T.; Haniffa, M.; Teichmann, S. A.

10.1101/2020.01.28.911115 — immunology — Posted on 2020-01-28

661 Mapping heritability of obesity by brain cell types

Timshel, P. N.; Thompson, J. J.; Pers, T. H.

10.1101/2020.01.27.920033 — genetics — Posted on 2020-01-28

662 Brain network dynamics fingerprints are resilient to data heterogeneity

Menara, T.; Lisi, G.; Cortese, A.

10.1101/2020.01.26.920637 — neuroscience — Posted on 2020-01-28

663 Morality recruits neural reward circuitry to shape economic decision making

Liu, J.; Huang, X.; Liao, C.; Cui, F.

10.1101/2020.01.27.920694 — neuroscience — Posted on 2020-01-28

664 Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3 upon binding to protease inhibitors

Phoo, W. W.; El Sahili, A.; Liew, C. W.; Lescar, J.; Vasudevan, S.; Luo, D.; Chen, M. W.

10.1101/2020.01.27.907089 — biochemistry — Posted on 2020-01-28

665 Latent space visualization, characterization, and generation of diverse vocal communication signals

Sainburg, T.; Thielk, M.; Gentner, T. Q.

10.1101/870311 — animal behavior and cognition — Posted on 2020-01-28

666 Breaking down of the healthcare system: Mathematical modelling for controlling the novel coronavirus (2019-nCoV) outbreak in Wuhan, China

Ming, W.-k.; Huang, J.; Zhang, C. J. P.

10.1101/2020.01.27.922443 — microbiology — Posted on 2020-01-28

667 Slicing the genome of star-fruit (Averrhoa carambola L.)

Fan, Y.; Sahu, S. K.; Yang, T.; Mu, W.; Wei, J.; Cheng, L.; Yang, J.; Xu, X.; Liu, X.; Mu, R.; Liu, J.; Zhao, J.; Zhao, Y.; Liu, H.

10.1101/851790 — genomics — Posted on 2020-01-28

668 Modelling the Putative Ancient Distribution of the Coastal Rock Pool Mosquito Aedes togoi

Peach, D. A.; Matthews, B. J.

10.1101/2020.01.21.914838 — zoology — Posted on 2020-01-28

669 Olfactory Response as a Marker for Alzheimer's Disease: Evidence from Perceptual and Frontal Oscillation Coherence Deficit

Sedghizadeh, M. J.; Hojjati, H.; Ezzatdoost, K.; Aghajan, H.; Vahabi, Z.; Tarighatnia, H.

10.1101/840934 — neuroscience — Posted on 2020-01-28

670 Novel neural signal features permit robust machine-learning of natural tactile- and proprioception-dominated dorsal column nuclei signals

Loutit, A. J.; Potas, J. R.

10.1101/831164 — neuroscience — Posted on 2020-01-28

671 Motion denoising of multiband resting state functional connectivity MRI data: An improved volume censoring method

Williams, J. C.; Van Snellenberg, J. X.

10.1101/860635 — neuroscience — Posted on 2020-01-28

672 Differential contributions of synaptic and intrinsic inhibitory currents to speech segmentation via flexible phase-locking in neural oscillators

Pittman-Polletta, B. R.; Wang, Y.; Stanley, D. A.; Schroeder, C. E.; Whittington, M. A.; Kopell, N. J.

10.1101/2020.01.11.902858 — neuroscience — Posted on 2020-01-28

673 Genetic diversity, structure, and kinship analysis of Trachemys venusta venusta in Wildlife Management Units and wild populations in south Mexico. Implications for conservation and management.

Lesher-Gordillo, j. M.; Recino-Reyes, E. B.; Machkour M'Rabet, S.; Gallardo-Alvarez, M. I.; Zenteno-Ruiz, C. E.; Olivera-Gomez, L. D.; Valdes-Marin, A.; Gomez-Carrasco, G. M.; Rios-Rodas, L.; Barragan-Vazquez, M. d. R.; Hernandez Martinez, R. M.

10.1101/2020.01.27.920983 — molecular biology — Posted on 2020-01-28

674 ASC oligomer favor caspase-1CARD domain recruitment after intracellular potassium efflux

Martin-Sanchez, F.; Compan, V.; Tapia-Abellan, A.; Gomez-Sanchez, A. I.; Banos, M. C.; Schmidt, F. I.; Pelegrin, P.

10.1101/2020.01.27.921239 — immunology — Posted on 2020-01-28

675 Conservation motifs - a novel evolutionary-based classification of proteins

Beer, H.; Sherill-Rofe, D.; Unterman, I.; Bloch, I.; Isseroff, M.; Stupp, D.; Sharon, E.; Zisman, E.; Tabach, Y.

10.1101/2020.01.12.903138 — evolutionary biology — Posted on 2020-01-28

676 Winter in water: Differential responses and the maintenance of biodiversity

McMeans, B.; McCann, K.; Guzzo, M.; Bartley, T.; Bieg, C.; Blanchfield, P.; Fernandes, T.; Giacomini, H.; Middel, T.; Rennie, M.; Ridgway, M.; Shuter, B.

10.1101/849109 — ecology — Posted on 2020-01-28

677 Climate change and intensive land use reduce soil animal biomass through dissimilar pathways

Yin, R.; Siebert, J.; Eisenhauer, N.; Schädler, M.

10.1101/2020.01.26.920330 — ecology — Posted on 2020-01-28

678 BANDITS: Bayesian differential splicing accounting for sample-to-sample variability and mapping uncertainty

Tiberi, S.; Robinson, M.

10.1101/750018 — bioinformatics — Posted on 2020-01-28

679 Robotic Stereotaxic System based on 3D skull reconstruction to improve surgical accuracy and speed

Ly, P. T.; Lucas, A.; Pun, S. H.; Dondzillo, A.; Liu, C.; Klug, A.; Lei, T.

10.1101/2020.01.04.894972 — bioengineering — Posted on 2020-01-28

680 Physiological and morphological correlates of extreme acid tolerance in larvae of the acidophilic amphibian Litoria cooloolensis

Meyer, E. A.; Franklin, C. E.; Cramp, R. L.

10.1101/2019.12.15.872259 — zoology — Posted on 2020-01-28

681 Streaming of repeated noise in primary and secondary fields of auditory cortex

Saderi, D.; Buran, B. N.; David, S. V.

10.1101/738583 — neuroscience — Posted on 2020-01-28

682 Maturation of cortical microstructure and cognitive development in childhood and adolescence: a T1w/T2w ratio MRI study

Norbom, L. B.; Rokicki, J.; Alnaes, D.; Kaufmann, T.; Doan, N. T.; Andreassen, O. A.; Westlye, L. T.; Tamnes, C. K.

10.1101/681221 — neuroscience — Posted on 2020-01-28

683 Phasic and tonic serotonin modulate alarm reactions and post-exposure behavior in zebrafish

Lima-Maximino, M.; Pyterson, M. P.; do Carmo Silva, R. X.; Gomes, G. C. V.; Rocha, S. P.; Herculano, A. M.; Rosemberg, D. B.; Maximino, C.

10.1101/827824 — neuroscience — Posted on 2020-01-28

684 A Vibrio Cholerae Core Genome Multilocus Sequence Typing Scheme to Facilitate the Epidemiological Study of Cholera

Liang, K. Y. H.; Orata, F. D.; Islam, M. T.; Nasreen, T.; Alam, M.; Tarr, C. L.; Boucher, Y. F.

10.1101/2020.01.27.919118 — microbiology — Posted on 2020-01-28

685 Edem1 activity in the fat body regulates insulin signalling and metabolic homeostasis in Drosophila

Pathak, H.; Varghese, J.

10.1101/671305 — developmental biology — Posted on 2020-01-28

686 STAGdb: a 30K SNP genotyping array and Science Gateway for Acropora corals and their dinoflagellate symbionts

Kitchen, S. A.; Von Kuster, G.; Vasquez Kuntz, K. L.; Reich, H. G.; Miller, W.; Griffin, S.; Fogarty, N. D.; Baums, I.

10.1101/2020.01.21.914424 — genetics — Posted on 2020-01-28

687 Glycopeptide variable window SWATH for improved Data Independent Acquisition glycoproteomics

Zhou, C.; Schulz, B. L.

10.1101/739615 — biochemistry — Posted on 2020-01-28

688 Experience-dependent modulation of the visual evoked potential: testing effect sizes, retention over time, and associations with age in 415 healthy individuals

Valstad, M.; Moberget, T.; Roelfs, D.; Slapo, N. B.; Timpe, C. M. F.; Beck, D.; Richard, G.; Saether, L. S.; Haatveit, B.; Skaug, K. A.; Nordvik, J. E.; Hatlestad-Hall, C.; Einevoll, G. T.; Mäki-Marttunen, T.; Westlye, L. T.; Jönsson, E. G.; Andreassen, O. A.; Elvsashagen, T.

10.1101/2020.01.27.916692 — neuroscience — Posted on 2020-01-28

689 Hypoxia mediated regulation of mitochondrial transcription factors: Implications of hypertensive renal physiology

Natarajan, B.; Arige, V.; Khan, A. A.; Reddy, S. S.; Bharthwal, M.; Mahapatra, N. R.

10.1101/816470 — molecular biology — Posted on 2020-01-28

690 RNPP-type quorum sensing regulates solvent formation and sporulation in Clostridium acetobutylicum

Kotte, A.-K.; Severn, O.; Bean, Z.; Schwarz, K.; Minton, N. P.; Winzer, K.

10.1101/106666 — microbiology — Posted on 2020-01-28

691 First description of a herpesvirus infection in genus Lepus

Abade dos Santos, F. A.; Monteiro, M.; Pinto, A.; Carvalho, C. L.; Peleteiro, M. C.; Carvalho, P.; Mendonca, P.; Carvalho, T.; Duarte, M. D.

10.1101/2020.01.21.913723 — microbiology — Posted on 2020-01-28

692 NLRP3- and AIM2-autonomy in a mouse model of MSU crystal-induced acute inflammation in vivo suggests imiquimod-dependent targeting of Il-1 expression as relevant therapy for gout patients.

Mariotte, A.; Decauwer, A.; Po, C.; Abou-Faycal, C.; Pichot, A.; Paul, N.; Aouadi, I.; Carapito, R.; Frisch, B.; Macquin, C.; Chatelus, E.; Sibilia, J.; Armspach, J.-P.; Bahram, S.; Georgel, P.

10.1101/772756 — immunology — Posted on 2020-01-28

693 Divergent effects of Western and Mediterranean diets on behavior and monocyte polarization.

Johnson, C. S. C.; Shively, C. A.; Michalson, K. T.; Lea, A. J.; DeBo, R. J.; Howard, T. D.; Hawkins, G. A.; Appt, S. E.; Liu, Y.; McCall, C. E.; Herrington, D.; Register, T. C.; Snyder-Mackler, N.

10.1101/2020.01.27.917567 — genomics — Posted on 2020-01-28

694 Stoichiometric constraints modulate the effects of temperature and nutrients on biomass distribution and community stability

Sentis, A.; Haegeman, B.; Montoya, J. M.

10.1101/589895 — ecology — Posted on 2020-01-28

695 Burden of tumor mutations, neoepitopes, and other variants are dubious predictors of cancer immunotherapy response and overall survival

Wood, M. A.; Weeder, B. R.; David, J. K.; Nellore, A.; Thompson, R. F.

10.1101/665026 — cancer biology — Posted on 2020-01-28

696 A unified simulation model for understanding the diversity of cancer evolution

Niida, A.; Hasegawa, T.; Innan, H.; Shibata, T.; Mimori, K.; Miyano, S.

10.1101/762997 — cancer biology — Posted on 2020-01-28

697 Removing mains power artefacts from EEG - a novel template-based method

Zhang, S.; McCane, B.; Neo, P. S.-H.; McNaughton, N.

10.1101/2020.01.27.911586 — bioengineering — Posted on 2020-01-28

698 Diversity and evolution of surface polysaccharide synthesis loci in Enterobacteriales

Holt, K. E.; Lassalle, F.; Wyres, K. L.; Wick, R.; Mostowy, R. J.

10.1101/709832 — evolutionary biology — Posted on 2020-01-28

699 ctDNAtools: An R package to work with sequencing data of circulating tumor DNA

Alkodsi, A.; Meriranta, L.; Pasanen, A.; Leppa, S.

10.1101/2020.01.27.912790 — bioinformatics — Posted on 2020-01-28

700 Rapid event-related, BOLD, NHP: choose two out of three

Pelekanos, V.; Mok, R.; Joly, O.; Ainsworth, M.; Kyriazis, D.; Kelly, M.; Bell, A.; Kriegeskorte, N.

10.1101/2020.01.27.919555 — neuroscience — Posted on 2020-01-28

701 ATRAID, a genetic factor that regulates the action of nitrogen-containing bisphosphonates on bone.

Surface, L. E.; Burrow, D. T.; Li, J.; Kumar, S.; Park, J.; Lyu, C.; Song, N.; Yu, Z.; Rajagopal, A.; Bae, Y.; Lee, B. H.; Mumm, S.; Gu, C. C.; Wan, F.; Baker, J. C.; Mohseni, M.; Sum, M.; Huskey, M.; Duan, S.; Bijanki, V. N.; Civitelli, R.; Gardner, M. J.; McAndrew, C. M.; Ricci, W. M.; Gurnett, C. A.; Diemer, K.; Shannon, K. M.; Raje, N.; Dodson, T. B.; Costantino, C. L.; Haber, D. A.; Carette, J. E.; Varadarajan, M.; Brummelkamp, T. R.; Birsoy, K.; Sabatini, D. M.; Haller, G.; Peterson, T. R.

10.1101/338350 — genomics — Posted on 2020-01-28

702 Tropomyosin 1 genetically constrains in vitro hematopoiesis

Thom, C. S.; Jobaliya, C. D.; Lorenz, K.; Maguire, J. A.; Gagne, A.; Gadue, P.; French, D. L.; Voight, B. F.

10.1101/631895 — genomics — Posted on 2020-01-28

703 Long-read sequencing reveals widespread intragenic structural variants in a recent allopolyploid crop plant

Chawla, H. S.; Lee, H.; Gabur, I.; Tamilselvan-Nattar-Amutha, S.; Obermeier, C.; Schiessl, S. V.; Song, J.-M.; Liu, K.; Guo, L.; Parkin, I. A. P.; Snowdon, R. J.

10.1101/2020.01.27.915470 — genomics — Posted on 2020-01-28

704 Size- and stage-dependence in cause-specific mortality of migratory brown trout

Nater, C. R.; Vindenes, Y.; Aass, P.; Cole, D.; Langangen, O.; Moe, J.; Rustadbakken, A.; Turek, D.; Vollestad, L. A.; Ergon, T.

10.1101/544742 — ecology — Posted on 2020-01-28

705 Extracellular ATP released from Candida albicans activates non-peptidergic neurons to augment host defense

Edwards, T.; Zhang, S.; Liu, A.; Cohen, J.; Zhou, P.; Mogavero, S.; hube, b.; berman, j.; bougnoux, m.-e.; mathers, a.; gaffen, s.; Albers, K. M.; koeber, h. r.; davis, b.; d'enfert, c.; Kaplan, D. H.

10.1101/2020.01.27.921049 — immunology — Posted on 2020-01-28

706 Tomato wall-associated kinase SlWak1 acts in an Fls2- and Fls3-dependent manner to promote apoplastic immune responses to Pseudomonas syringae

Zhang, N.; Pombo, M. A.; Rosli, H. G.; Martin, G. B.

10.1101/2020.01.27.921460 — plant biology — Posted on 2020-01-28

707 The complete chloroplast genome sequence of American elm (Ulmus americana) and comparative genomics of related species

Ebrahimi, A.; Antonides, J. D.; Pinchot, C. C.; Slavicek, J. M.; Flower, C. E.; Woeste, K. E.

10.1101/2020.01.27.920181 — genomics — Posted on 2020-01-28

708 Thermodynamics of Homopeptide Aggregation

Phan, T. T. M.; Schmit, J. D.

10.1101/2020.01.27.921700 — biophysics — Posted on 2020-01-28

709 Analyses of Multi-dimensional Single Cell Trajectories Quantify Transition Paths Between Nonequilibrium Steady States

Wang, W.; Xing, J.

10.1101/2020.01.27.920371 — biophysics — Posted on 2020-01-28

710 Analysis of zebrafish periderm enhancers facilitates identification of a regulatory variant near human KRT8/18

Liu, H.; Duncan, K.; Helverson, A.; Kumari, P.; Mumm, C.; Xiao, Y.; Carlson, J. C.; Darbellay, F.; Visel, A.; Leslie, E.; Breheny, P.; Erives, A. J.; Cornell, R.

10.1101/2020.01.27.921320 — developmental biology — Posted on 2020-01-28

711 An instructive role for IL7RA in the development of human B-cell precursor leukemia.

Geron, I.; Savino, A. M.; Tal, N.; Fishman, H.; Brown, J.; Turati, V.; James, C.; Sarno, J.; Lee, Y. N.; Rein Gil, A.; Birger, Y.; Muler, I.; Hameiri-Grossman, M.; Marcu-Malina, V.; Parnas, O.; Fischer, U.; Muschen, M.; Borkhard, A.; Kirsch, I. R.; Nagler, A.; Enver, T.; Izraeli, S.

10.1101/2020.01.27.919951 — cancer biology — Posted on 2020-01-28

712 Conditioned media from MCF7 and BT474 breast cancer cells induce insulin resistance in skeletal muscle myotubes

Ali, M. S.; Han, X.; Li, J.; Jaattela, M.; Sylow, L.

10.1101/2020.01.27.921262 — cancer biology — Posted on 2020-01-28

713 Biomolecular condensates undergo a generic shear-mediated liquid-to-solid transition

Shen, Y.; Ruggeri, F. S.; Vigolo, D.; Kamada, A.; Qamar, S.; Levin, A.; Iserman, C.; Alberti, S.; St George-Hyslop, P.; Knowles, T.

10.1101/2020.01.21.912857 — biophysics — Posted on 2020-01-28

714 Evolution of vertebrate gill covers via shifts in an ancient Pou3f3 enhancer

Barske, L.; Fabian, P.; Hirschberger, C.; Jandzik, D.; Square, T. A.; Xu, P.; Nelson, N.; Yu, H. V.; Medeiros, D. M.; Gillis, A.; Crump, G.

10.1101/2020.01.27.918193 — developmental biology — Posted on 2020-01-28

715 AMPK activation by metformin promotes survival of dormant ER+ breast cancer cells

Hampsch, R. A.; Wells, J. D.; Traphagen, N. A.; McCleery, C. F.; Fields, J. L.; Shee, K.; Dillon, L. M.; Pooler, D. B.; Lewis, L. D.; Demidenko, E.; Huang, Y. H.; Marotti, J. D.; Kinlaw, W.; Miller, T. W.

10.1101/2020.01.21.914382 — cancer biology — Posted on 2020-01-28

716 PDZ and LIM domain protein 2 plays dual and context-dependent roles in breast cancer development

Maryas, J.; Pribyl, J.; Bouchalova, P.; Skladal, P.; Bouchal, P.

10.1101/2020.01.27.920199 — cancer biology — Posted on 2020-01-28

717 Identifying Priority Landscapes for Conservation of Snow Leopards in Pakistan

Hameed, S.; Din, J. u.; Ali, H.; Kabir, M.; Younas, M.; Hao, W.; Bischof, R.; Nawaz, M. A.

10.1101/2020.01.27.920975 — zoology — Posted on 2020-01-27

718 Culex erythrothorax: Insecticide Susceptibility and Mosquito Control

Esterly, A.; Alemayehu, D.; Rusmisel, B.; Busam, J.; Shelton, T.; Sebay, T.; Zahiri, N.; Huston, J.; Clausnitzer, R.; Haas-Stapleton, E.

10.1101/2020.01.27.921007 — zoology — Posted on 2020-01-27

719 Effect of irradiation on the survival and susceptibility of female Anopheles arabiensis to natural isolates of Plasmodium falciparum

Guissou, E.

10.1101/2020.01.27.919530 — systems biology — Posted on 2020-01-27

720 Systematically gap-filling the genome-scale model of CHO cells

Fouladiha, H.; Marashi, S.-A.; Li, S.; Vaziri, B.; Lewis, N. E.

10.1101/2020.01.27.921296 — systems biology — Posted on 2020-01-27

721 Effects of C-peptide replacement therapy on bone microarchitecture parameters in streptozotocin-diabetic rats.

Maurotti, S.; Russo, C.; Musolino, V.; Nucera, S.; Gliozzi, M.; Scicchitano, M.; Bosco, F.; Morittu, V. M.; Ragusa, M.; Mazza, E.; Gazzaruso, C.; Britti, D.; Valenti, M. T.; Deiana, M.; Romeo, S.; Giannini, S.; Dalle Carbonare, L.; Mollace, V.; Pujia, A.; Montalcini, T.

10.1101/2020.01.27.921288 — systems biology — Posted on 2020-01-27

722 Disparities in information on Long-Acting Reversible Contraceptives available to college students on student health center websites in USA

Kulkarni, A.; Belsare, T.; Shah, R.; Yu Yu, D.; Holschuh, C.; Kakar, V.; Modrek, S.; Smirnova, A.

10.1101/2020.01.27.920926 — scientific communication and education — Posted on 2020-01-27

723 Probiotics for the prevention of antibiotic-associated adverse events in children - a systematic review to inform development of a core outcome set

Łukasik, J.; Guo, Q.; Boulos, L.; Szajewska, H.; Johnston, B. C.

10.1101/2020.01.27.920892 — scientific communication and education — Posted on 2020-01-27

724 Dietary and Biological Assessment of Omega-3 Status of Collegiate Athletes: A Cross-Sectional Analysis

Ritz, P.; Rogers, M.; Zabinsky, J.; Hedrick, V.; Rockwell, J.; Rimer, E.; Kostelnik, S.; Hulver, M.; Rockwell, M.

10.1101/2020.01.27.920991 — pharmacology and toxicology — Posted on 2020-01-27

725 pH effect on strain-specific transcriptomes of the take-all fungus

GAZENGEL, K.; LEBRETON, L.; LAPALU, N.; AMSELEM, J.; GUILLERM-ERCKELBOUDT, A.-Y.; TAGU, D.; DAVAL, S.

10.1101/2020.01.27.921023 — pathology — Posted on 2020-01-27

726 Canine cognitive dysfunction (CCD) patients have reduced total hippocampal volumes compared with aging control dogs: a comparative MRI study

Dewey, C. W.; Rishniw, M.; Platt, S.; Robinson, K.; Sackman, J.; O'Donnell, M.

10.1101/2020.01.27.920918 — neuroscience — Posted on 2020-01-27

727 Obesity: can environmental food odours make you lose control? Investigation of implicit priming effects on reactivity and inhibitory control towards foods

MAS, M.; Brindisi, M.-C.; Chabanet, C.; Chambaron, S.

10.1101/2020.01.27.920967 — neuroscience — Posted on 2020-01-27

728 MicroRNA-9 Mediated the Protective Effect of Ferulic Acid on Hypoxic-Ischemic Brain Injury in Neonatal Rats

Yao, K.; Yang, Q.; Li, Y.; Lan, T.; Yu, H.; Yu, Y.

10.1101/2020.01.27.920900 — neuroscience — Posted on 2020-01-27

729 Robust point-process Granger causality analysis in presence of exogenous temporal modulations and trial-by-trial variability in spike trains.

Casile, A.; Faghih, R. T.; Brown, E. N.

10.1101/2020.01.27.920868 — neuroscience — Posted on 2020-01-27

730 Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids

Deleidi, M.; Dina, I.; Perez, M. J.; Panagiotakopoulou, V.; Di Napoli, G.; Brunetti, D.; Al-Shaana, R.; Kaeser, S. A.; Jucker, M.; Zeviani, M.; Viscomi, C.

10.1101/2020.01.27.919522 — neuroscience — Posted on 2020-01-27

731 Dynamic Order in Allosteric Interactions

Tureli, S.; Haliloglu, T.

10.1101/2020.01.27.920850 — molecular biology — Posted on 2020-01-27

732 Antibiotic-induced DNA damage results in a controlled loss of pH homeostasis and genome instability

Booth, J. A.; Spirek, M.; Lobie, T. A.; Skarstad, K.; Krejci, L.; Bjoras, M.

10.1101/2020.01.27.921072 — microbiology — Posted on 2020-01-27

733 Highly Efficient Antibiofilm and Antifungal Activity of Green Propolis against Candida species in dentistry material

Bezerra, C. R. F.; Assuncao Borges, K. R.; Alves, R. d. N. S.; Teles, A. M.; Pimentel Rodrigues, I. V.; da Silva, M. A. C. N.; Nascimento, M. d. D. S. B.; Bezerra, G. F. d. B.

10.1101/2020.01.27.920959 — microbiology — Posted on 2020-01-27

734 Quantifying memory CD8 T cell-mediated immune pressure on influenza A virus infection in vivo

Li, Z.-R. T.; Zarnitsyna, V. I.; Lowen, A. C.; Antia, R.; Kohlmeier, J. E.

10.1101/2020.01.27.921031 — immunology — Posted on 2020-01-27

735 Long-read Assays Shed New Light on the Transcriptome Complexity of a Viral Pathogen and on Virus-Host Interaction

Tombacz, D.; Prazsak, I.; Maroti, Z.; Moldovan, N.; Csabai, Z.; Balazs, Z.; Denes, B.; Kalmar, T.; Snyder, M.; Boldogkoi, Z.

10.1101/2020.01.27.921056 — genomics — Posted on 2020-01-27

736 Shikonin induces odontoblastic differentiation of dental pulp stem cells via AKT-mTOR signaling in the presence of CD44

Umemura, N.; Kajiura, K.; Ohkoshi, E.; Ohta, T.; Kondoh, N.; Kawano, S.

10.1101/2020.01.27.921015 — cell biology — Posted on 2020-01-27

737 A single Ho-induced double-strand break at the MAT locus is lethal in Candida glabrata

Maroc, L.; Zhou-Li, Y.; Boisnard, S.; Fairhead, C.

10.1101/2020.01.27.920876 — genetics — Posted on 2020-01-27

738 Evolution of transmissible spongiform encephalopathy and the prion protein gene (PRNP) in mammals

Buchanan, B.; Zink, R. M.

10.1101/2020.01.27.920942 — evolutionary biology — Posted on 2020-01-27

739 Heterogeneity of proteome dynamics between connective tissue phases of adult tendon

Simpson, D.; Choi, H.; Wang, D.; Prescott, M.; Pitsillides, A. A.; Dudhia, J.; Clegg, P. D.; Ping, P.; Thorpe, C. T.

10.1101/2020.01.27.921163 — biochemistry — Posted on 2020-01-27

Mitra, A.; Sarkar, A.; Szabo, M. R.; Borics, A.

10.1101/2020.01.27.920769 — molecular biology — Posted on 2020-01-27

741 Discovery of a spatially and temporally persistent core microbiome of the common bean rhizosphere

Stopnisek, N.; Shade, A.

10.1101/727461 — microbiology — Posted on 2020-01-27

742 Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods

Lewis, S. H.; Ross, L.; Bain, S.; Pahita, E.; Smith, S. A.; Cordaux, R.; Miska, E.; Lenhard, B.; Jiggins, F. M.; Sarkies, P.

10.1101/2020.01.27.920108 — genetics — Posted on 2020-01-27

743 Metagenomic analysis of a blood stain from the French revolutionary Jean-Paul Marat (1743-1793)

de Dios, A.; van Dorp, L.; Charlier, P.; Morfopoulou, S.; Lizano, E.; Bon, C.; Le Bitouze, C.; Alvarez-Estape, M.; Marques-Bonet, T.; Balloux, F.; Lalueza-Fox, C.

10.1101/825034 — genetics — Posted on 2020-01-27

744 The first eukaryotic kinome tree illuminates the dynamic history of present-day kinases

Snel, B.; van Wijk, L. M.

10.1101/2020.01.27.920793 — evolutionary biology — Posted on 2020-01-27

745 AERON: Transcript quantification and gene-fusion detection using long reads

Rautiainen, M.; Durai, D.; Chen, Y.; Xin, L.; Low, H. M.; Goeke, J.; Marschall, T.; Schulz, M.

10.1101/2020.01.27.921338 — bioinformatics — Posted on 2020-01-27

746 Are skyline plot-based demographic estimates overly dependent on smoothing prior assumptions?

Parag, K. V.; Pybus, O.; Wu, C.-H.

10.1101/2020.01.27.920215 — genetics — Posted on 2020-01-27

747 Levy walks emerging near a critical point

Abe, M. S.

10.1101/2020.01.27.920801 — ecology — Posted on 2020-01-27

748 Shifts in gut microbiome and metabolome are associated with risk of recurrent atrial fibrillation

Zuo, K.; Li, J.; Zhang, J.; Wang, P.; Jiao, J.; Liu, Z.; Yin, X.; Liu, X.; Li, K.; Yang, X.

10.1101/2020.01.26.920587 — genomics — Posted on 2020-01-27

749 Cooperativity of membrane-protein and protein-protein interactions control membrane remodeling by epsin 1 and regulate clathrin-mediated endocytosis

Meinecke, M.; Kroppen, B.; Teske, N.; Yambire, K.; Denkert, N.; Murkhejee, I.; Tarasenko, D.; Jaipuria, G.; Zweckstetter, M.; Milosevic, I.; Steinem, C.

10.1101/2020.01.27.920827 — biophysics — Posted on 2020-01-27

750 Super-resolved live-cell imaging using Random Illumination Microscopy

Mangeat, T.; Labouesse, S.; Allain, M.; Poincloux, R.; Bouissou, A.; Cantaloube, S.; Courtais, E.; Vega, E.; Li, T.; Guenole, A.; Rouviere, C.; Allard, S.; Campo, N.; Suzanne, M.; Wang, X.; Michaux, G.; Pinot, M.; Le Borgne, R.; Tournier, S.; Idier, J.; Sentenac, A.

10.1101/2020.01.27.905083 — bioengineering — Posted on 2020-01-27

751 Spinach growers value host resistance and synthetic fungicides in the fight against downy mildew

Choudhury, R. A.; McRoberts, N.

10.1101/2020.01.20.913129 — scientific communication and education — Posted on 2020-01-27

752 A global lipid map defines a network essential for Zika virus replication

Leier, H. C.; Weinstein, J. B.; Kyle, J. E.; Lee, J.-Y.; Bramer, L. M.; Stratton, K. G.; Kempthorne, D.; Navratil, A. R.; Tafesse, E. G.; Hornemann, T.; Messer, W. B.; Dennis, E. A.; Metz, T. O.; Barklis, E.; Tafesse, F. G.

10.1101/2020.01.27.910919 — microbiology — Posted on 2020-01-27

753 Evaluating the accuracy of a smartphone-based artificial intelligence system, PlantVillage Nuru, in identifying the viral diseases of cassava

Mrisho, L. M.; Mbilinyi, N.; Ndalahwa, M.; Ramcharan, A. M.; Kehs, A.; McCloskey, P.; Murithi, H.; Hughes, D. P.; Legg, J.

10.1101/2020.01.26.919449 — plant biology — Posted on 2020-01-27

754 Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women

Trakoshis, S.; Martinez-Canada, P.; Rocchi, F.; Canella, C.; You, W.; Chakrabarti, B.; Ruigrok, A. N.; Bullmore, E.; Suckling, J.; Markicevic, M.; Zerbi, V.; MRC AIMS Consortium, ; Baron-Cohen, S.; Panzeri, S.; Gozzi, A.; Lai, M.-C.; Lombardo, M. V.

10.1101/2020.01.16.909531 — neuroscience — Posted on 2020-01-27

755 A mosaic renal myeloid subtype with T-cell inhibitory and protumoral features is linked to immune escape and survival in clear cell renal cell cancer

Brech, D.; Straub, T.; Kokolakis, E.; Irmler, M.; Beckers, J.; Buettner, F.; Schaeffeler, E.; Winter, S.; Schwab, M.; Nelson, P. J.; Noessner, E.

10.1101/2020.01.20.912865 — immunology — Posted on 2020-01-27

756 A mediation analysis of schizophrenia variants: Risk alleles may affect a gene's expression differently from how the expression affects risk

Peng, X.; Bader, J. S.; Avramopoulos, D.

10.1101/2020.01.27.904680 — genetics — Posted on 2020-01-27

757 Caffeine stabilises fission yeast Wee1 in a Rad24-dependent manner but attenuates its expression in response to DNA damage identifying a putative role for TORC1 in mediating its effects on cell cycle progression

Alao, J.-P.; Johansson-Sjolander, J.; Rallis, C.; Sunnerhagen, P.

10.1101/2020.01.22.915231 — cell biology — Posted on 2020-01-27

758 Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3 upon binding to protease inhibitors

Phoo, W. W.; El Sahili, A.; Liew, C. W.; Lescar, J.; Vasudevan, S.; Luo, D.; Chen, M. W.

10.1101/2020.01.27.907089 — biochemistry — Posted on 2020-01-27

759 A synthetic biochemical device for sensing microgravity

Mukhopadhyay, S.; Bagh, S.

10.1101/2020.01.26.920629 — synthetic biology — Posted on 2020-01-27

760 An in vivo strategy for knockdown of circular RNAs

Reddy, N.; Patop, I. L.; Krishnamoorthy, A.; Ashwal-Fluss, R.; Bartok, O.; Kadener, S.

10.1101/2020.01.23.916809 — molecular biology — Posted on 2020-01-27

761 Pollinators in food webs: Mutualistic interactions increase diversity, stability, and function in multiplex networks

Hale, K. R. S.; Valdovinos, F. S.; Martinez, N. D.

10.1101/791707 — ecology — Posted on 2020-01-27

762 The Effects of Motor Modularity on Performance, Generalizability and Learning in Upper-Extremity Reaching: a Computational Analysis

Al Borno, M.; Hicks, J. L.; Delp, S.

10.1101/804096 — physiology — Posted on 2020-01-27

763 Ultra-high field imaging reveals increased whole brain connectivity underpins cognitive strategies that attenuate pain

Schulz, E.; Stankewitz, A.; Winkler, A. M.; Irving, S.; Witkovsky, V.; Tracey, I.

10.1101/802306 — neuroscience — Posted on 2020-01-27

764 Non-spherical coacervate shapes in an enzyme driven active system

Spoelstra, W. K.; van der Sluis, E. O.; Dogterom, M.; Reese, L.

10.1101/714261 — biophysics — Posted on 2020-01-27

765 Perceptual spatial suppression and sensitivity for motion in schizophrenia

Linares, D.; Amoretti, S.; Marin-Campos, R.; Sousa, A.; Prades, L.; Dalmau, J.; Bernardo, M.; Compte, A.

10.1101/799395 — neuroscience — Posted on 2020-01-27

766 FMRP Control of Ribosome Translocation Promotes Chromatin Modifications and Alternative Splicing of Neuronal Genes Linked to Autism

Shah, S.; Molinaro, G.; Liu, B.; Wang, R.; Huber, K.; Richter, J.

10.1101/801076 — neuroscience — Posted on 2020-01-27

767 High-throughput analysis of adaptation using barcoded strains of Saccharomyces cerevisiae

Fasanello, V. J.; Liu, P.; Botero, C. A.; Fay, J. C.

10.1101/731349 — evolutionary biology — Posted on 2020-01-27

768 Global and local mechanical properties control endonuclease reactivity of a DNA origami nanostructure

Suma, A.; Stopar, A.; Nicholson, A. W.; Castronovo, M.; Carnevale, V.

10.1101/640847 — biophysics — Posted on 2020-01-27

769 Neuro-transcriptomic signatures for mood disorder morbidity and suicide mortality

Jabbi, M.; Arasappan, D.; Eickhoff, S. B.; Strakowski, S. M.; Nemeroff, C. B.; Hofmann, H.

10.1101/762492 — neuroscience — Posted on 2020-01-27

770 Geographic variation in the genetic basis of resistance to leaf rust between locally adapted ecotypes of the biofuel crop switchgrass (Panicum virgatum)

VanWallendael, A.; Bonnette, J.; Juenger, T. E.; Fritschi, F. B.; Fay, P. A.; Mitchell, R. B.; Lloyd-Reilley, J.; Rouquette, F.; Bergstrom, G. C.; Lowry, D. B.

10.1101/619148 — genomics — Posted on 2020-01-27

771 Transcriptome-guided parsimonious flux analysis improves predictions with metabolic networks in complex environments

Jenior, M. L.; Moutinho, T.; Dougherty, B. V.; Papin, J. A.

10.1101/637124 — systems biology — Posted on 2020-01-27

772 A dual foveal-peripheral visual processing model implements efficient saccade selection

Dauce, E.; Albiges, P.; Perrinet, L. U.

10.1101/725879 — neuroscience — Posted on 2020-01-27

773 Water and phosphorus uptake by upland rice root systems unraveled under multiple scenarios: linking a 3D soil-root model and data

De Bauw, P.; Mai, T.; Schnepf, A.; Merckx, R.; Smolders, E.; Vanderborght, J.

10.1101/2020.01.27.921247 — developmental biology — Posted on 2020-01-27

774 Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition

Xu, W.; Cao, L.; Hao, H.

10.1101/2020.01.27.921122 — cell biology — Posted on 2020-01-27

775 Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology

Kargapolova, Y.; Rehimi, R.; Kayserli, H.; Bruehl, J.; Zirkel, A.; Li, Y.; Yigit, G.; Hoischen, A.; Frank, S.; Russ, N.; Trautwein, J.; Laugsch, M.; Gusmao, E. G.; Josipovic, N.; Altmeuller, J.; Nuernberg, P.; Laengst, G.; Kaiser, F. J.; Watrin, E.; Brunner, H.; Rada-Iglesias, A.; Kurian, L.; Wollnik, B.; Bouazoune, K.; Papantonis, A.

10.1101/2020.01.27.921171 — cell biology — Posted on 2020-01-27

776 Intra-mitochondrial proteostasis is directly coupled to alpha-synuclein and Amyloid β 1-42 pathology

Lautenschlaeger, J.; Wagner-Valladolid, S.; Stephens, A. D.; Fernandez-Villegas, A.; Hockings, C.; Mishra, A.; Manton, J. D.; Fantham, M. J.; Lu, M.; Rees, E. J.; Kaminski, C. F.; Kaminski Schierle, G. S.

10.1101/561134 — neuroscience — Posted on 2020-01-27

777 Taxonomic variability over functional stability in the microbiome of Cystic Fibrosis patients chronically infected by Pseudomonas aeruginosa

Bacci, G.; Taccetti, G.; Dolce, D.; Armanini, F.; Segata, N.; Di Cesare, F.; Lucidi, V.; Fiscarelli, E. V.; Morelli, P.; Casciaro, R.; Negroni, A.; Mengoni, A.; Bevivino, A.

10.1101/609057 — microbiology — Posted on 2020-01-27

778 Stoichiometric constraints modulate the effects of temperature and nutrients on biomass distribution and community stability

Sentis, A.; Haegeman, B.; Montoya, J. M.

10.1101/589895 — ecology — Posted on 2020-01-27

779 Full-genome evolutionary analysis of the novel corona virus (2019-nCoV) rejects the hypothesis of emergence as a result of a recent recombination event

Paraskevis, D.; Kostaki, E. G.; Magiorkinis, G.; Panayiotakopoulos, G.; Tsiodras, S.

10.1101/2020.01.26.920249 — microbiology — Posted on 2020-01-27

780 Interplay between historical and current features of the cityscape in shaping the genetic structure of the house mouse (Mus musculus domesticus) in Dakar (Senegal, West Africa)

Stragier, C.; Piry, S.; Loiseau, A.; Kane, M.; Sow, A.; Niang, Y.; Diallo, M.; Ndiaye, A.; Gauthier, P.; Borderon, M.; Granjon, L.; Brouat, C.; Berthier, K.

10.1101/557066 — ecology — Posted on 2020-01-27

781 High fidelity estimates of spikes and subthreshold waveforms from 1-photon voltage imaging in vivo

Xie, M.; Adam, Y.; Fan, L.; Boehm, U. L.; Kinsella, I. A.; Zhou, D.; Paninski, L.; Cohen, A. E.

10.1101/2020.01.26.920256 — neuroscience — Posted on 2020-01-27

782 Thm2 interacts with paralog, Thm1, and sensitizes to Hedgehog signaling in postnatal skeletogenesis

Allard, B. A.; Wang, W.; Pottorf, T. S.; Mumtaz, H.; Silva, L. M.; Jacobs, D. T.; Wang, J.; Bumann, E. E.; Tran, P. V.

10.1101/2020.01.26.920165 — developmental biology — Posted on 2020-01-27

783 Giant magnetoresistive biosensors for real-time quantitative detection of protease activity

Adem, S.; Jain, S.; Sveiven, M.; Zhou, X.; O'Donoghue, A. J.; Hall, D. A.

10.1101/2020.01.26.917476 — bioengineering — Posted on 2020-01-27

784 Nanoscale Chromatin Imaging and Analysis (nano-ChIA) platform bridges 4-D chromatin organization with molecular function

LI, Y.; Eshein, A.; Virk, R.; Eid, A.; Wu, W.; Frederick, J.; VanDerway, D.; Gladstein, S.; Huang, K.; Anthony, N.; Bauer, G.; Zhou, X.; Agrawal, V.; Pujadas, E.; Chandler, J.; Nguyen, T.-Q.; Bleher, R.; de Pablo, J.; Szleifer, I.; Dravid, V. P.; Almassalha, L. M.; Backman, V.

10.1101/2020.01.26.920363 — genomics — Posted on 2020-01-27

785 GS-Preprocess: Containerized GUIDE-seq Data Analysis Tools with Diverse Sequencer Compatibility

Rodriguez, T. C.; Pratt, H. E.; Liu, P.; Amrani, N.; Zhu, L. J.

10.1101/2020.01.26.914861 — bioinformatics — Posted on 2020-01-27

786 Transcriptional regulator PAX4 links Receptor Tyrosine Kinases and cytoskeleton stability in Alzheimer's disease and type 2 diabetes

Majumder, P.; Chanda, K.; Das, D.; Chakrabarti, P.; Singh, B.; Jana, N. R.; Mukhopadhyay, D.

10.1101/2020.01.26.920512 — neuroscience — Posted on 2020-01-27

787 Purine-responsive expression of the Leishmania donovani NT3 purine nucleobase transporter is mediated by a conserved RNA stem-loop

Licon, M. H.; Yates, P. A.

10.1101/2020.01.26.920504 — molecular biology — Posted on 2020-01-27

788 Immune dysregulation in SHARPIN-deficient mice is dependent on CYLD-mediated cell death

Ang, R. L.; Sundberg, J. P.; Sun, S.-C.; Gillespie, V. L.; Heeger, P.; Xiong, H.; Lira, S. A.; Ting, A. T.

10.1101/2020.01.27.919076 — immunology — Posted on 2020-01-27

789 Transient "rest" induces functional reinvigoration and epigenetic remodeling in exhausted CAR-T cells

Weber, E. W.; Lynn, R. C.; Parker, K. R.; Anbunathan, H.; Lattin, J.; Sotillo, E.; Good, Z.; Malipatlolla, M.; Xu, P.; Vandris, P.; Majzner, R. G.; Qi, Y.; Chen, L.-C.; Gentles, A. J.; Wandless, T. J.; Satpathy, A. T.; Chang, H. Y.; Mackall, C. L.

10.1101/2020.01.26.920496 — immunology — Posted on 2020-01-27

790 Mapping Functional Protein Neighborhoods in the Mouse Brain

Liebeskind, B. J.; Young, R. L.; Halling, D. B.; Aldrich, R. W.; Marcotte, E. M.

10.1101/2020.01.26.920447 — systems biology — Posted on 2020-01-27

791 Opposing neural signals of CaV1-encoded peptides are tuned by C-terminus mediated inhibition

Yang, Y.; Liu, M.; Liu, N.; Li, W.; Yu, Z.; Hong, W.; Li, P.; Jiang, H.; Ge, H.; Wang, P.; Song, S.; Li, X.; Fan, Y.; Liu, X.

10.1101/2020.01.26.920348 — neuroscience — Posted on 2020-01-27

792 Visual response characteristics in lateral and medial subdivisions of the rat pulvinar

Foik, A. T.; Scholl, L. R.; Lean, G. A.; Lyon, D. C.

10.1101/2020.01.26.920454 — neuroscience — Posted on 2020-01-27

793 Computational front end to diverse therapeutic phage cocktails

Mageeney, C. M.; Sinha, A.; Mosesso, R. A.; Medlin, D. L.; Lau, B. Y.; Rokes, A. B.; Lane, T. W.; Branda, S. S.; Williams, K. P.

10.1101/2020.01.26.918771 — microbiology — Posted on 2020-01-27

794 C. elegans reads bacterial non-coding RNAs to learn pathogenic avoidance

Kaletsky, R.; Moore, R. S.; Vrla, G. D.; Parsons, L. L.; Gitai, Z.; Murphy, C. T.

10.1101/2020.01.26.920322 — genetics — Posted on 2020-01-27

795 A Multivariate View of Parallel Evolution

De Lisle, S.; Bolnick, D. I.

10.1101/2020.01.26.920439 — evolutionary biology — Posted on 2020-01-27

796 PARP1 and MGMT interaction-based sensitivity to DNA damage in Ewing sarcoma

Alimbetov, D.; Cropper, J.; Likhotvorik, R.; Carlson, R.; Kwon, Y.; Kurmasheva, R.

10.1101/2020.01.26.920405 — biochemistry — Posted on 2020-01-27

797 How Many Streamlines are Required for Reliable Probabilistic Tractography? Solutions for Microstructural Measurements and Neurosurgical Planning

Reid, L. B.; Cespedes, M. I.; Pannek, K.

10.1101/2020.01.26.920397 — bioinformatics — Posted on 2020-01-27

798 Temporal selectivity declines in the aging human auditory cortex

Erb, J.; Schmitt, L.-M.; Obleser, J.

10.1101/2020.01.24.919126 — neuroscience — Posted on 2020-01-27

799 Drug susceptibility profiling of Australian Burkholderia species as models for developing melioidosis therapeutics

Amiss, A. S.; Webb, J. R.; Mayo, M.; Currie, B. J.; Craik, D. J.; Troeira Henriques, S.; Lawrence, N.

10.1101/2020.01.21.914846 — microbiology — Posted on 2020-01-27

800 Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells

Bennstein, S. B.; Weinhold, S.; Manser, A. R.; Scherenschlich, N.; Noll, A.; Raba, K.; Kögler, G.; Walter, L.; Uhrberg, M.

10.1101/2020.01.24.918318 — immunology — Posted on 2020-01-27

801 A semi-empirical model of the aerodynamics of manoeuvring insect flight

Taylor, G. K.; Walker, S. M.

10.1101/2020.01.09.900654 — biophysics — Posted on 2020-01-27

802 Pathway Mining and Data Mining in Functional Genomics. An Integrative Approach to Delineate Boolean Relationships between Src and Its Targets

Piran, M.; Fernandes, P. L.; Sepahi, N.; Piran, M.; Rahimi, A.

10.1101/2020.01.25.919639 — bioinformatics — Posted on 2020-01-27

803 An Automated Addressable Microfluidics Device for Minimally-Invasive Manipulation of Cells and Fluids within Living Cultures

Tong, A.; Pham, L. Q.; Shah, V.; Naik, A.; Abatemarco, P.; Voronov, R.

10.1101/688424 — bioengineering — Posted on 2020-01-27

804 The gift of gab: probing the limits of dynamic concentration-sensing across a network of communicating cells

Bahadorian, M.; Zechner, C.; Modes, C.

10.1101/790907 — systems biology — Posted on 2020-01-27

805 Live cell imaging and analysis reveal cell phenotypic transition dynamics inherently missing in snapshot data

Wang, W.; Douglas, D. L.; Zhang, J.; Chen, Y.-J.; Cheng, Y.-Y.; Kumari, S.; Enuameh, M. S.; Dai, Y.; Wallace, C. T.; Watkins, S. C.; Shu, W.; Xing, J.

10.1101/2019.12.12.874248 — systems biology — Posted on 2020-01-27

806 Systems Biomedicine of Colorectal Cancer Reveals Potential Targets for CRC treatment

Piran, M.; Piran, M.; Sepahi, N.; Rahimi, A.

10.1101/2020.01.25.919415 — systems biology — Posted on 2020-01-27

807 SBOL Visual 2 Ontology

Misirli, G.; Beal, J.; Gorochowski, T. E.; Stan, G.-B.; Wipat, A.; Myers, C.

10.1101/2020.01.24.918417 — synthetic biology — Posted on 2020-01-27

808 Use of high-refractive index hydrogels and tissue clearing for large biological sample imaging

Richardson, A.; Fok, S.; Lee, V.; Rye, K.-A.; Di Girolamo, N.; Cochran, B. J.

10.1101/2020.01.22.905695 — pathology — Posted on 2020-01-27

809 Theta oscillations coincide with sustained hyperpolarization in CA3 pyramidal cells, underlying decreased firing

Malezieux, M.; Kees, A. L.; Mulle, C.

10.1101/652461 — neuroscience — Posted on 2020-01-27

810 From SARS-CoV to Wuhan 2019-nCoV Outbreak: Similarity of Early Epidemic and Prediction of Future Trends

Chen, Z.; Zhang, W.; Lu, Y.; Guo, C.; Guo, Z.; Liao, C.; Zhang, X.; Zhang, Y.; Han, X.; Li, Q.; Lipkin, W. I.; Lu, J.

10.1101/2020.01.24.919241 — microbiology — Posted on 2020-01-27

811 Origin time and epidemic dynamics of the 2019 novel coronavirus

Zhang, C.; Wang, M.

10.1101/2020.01.25.919688 — microbiology — Posted on 2020-01-27

812 Replaying the evolutionary tape to investigate subgenome dominance in allopolyploidBrassica napus

Bird, K. A.; Niederhuth, C.; Ou, S. A.; Gehan, M. A.; Pires, J. C.; Xiong, Z.; VanBuren, R.; Edger, P. P.

10.1101/814491 — evolutionary biology — Posted on 2020-01-27

813 Illness, social disadvantage, and sexual risk behavior in adolescence and the transition to adulthood

Alley, J.; Owen, R. Y.; Wawrzynski, S. E.; Lasrich, L.; Ahmmad, Z.; Utz, R.; Adkins, D. E.

10.1101/419010 — epidemiology — Posted on 2020-01-27

814 An Autoencoder and Artificial Neural Network-based Method to Estimate Parity Status of Wild Mosquitoes from Near-infrared Spectra

Milali, M. P.; Kiware, S. S.; Govella, N. J.; Okumu, F.; Bansal, N.; Bozdag, S.; Charlwood, J. D.; Maia, M. F.; Ogoma, S. B.; Dowell, F. E.; Corliss, G. F.; Sikulu-Lord, M. T.; Povinelli, R. J.

10.1101/2020.01.25.919878 — bioinformatics — Posted on 2020-01-27

815 BACTERIAL GROWTH INDUCED BIOCEMENTATION TECHNOLOGY, 'SPACE BRICK' - A PROPOSAL FOR EXPERIMENT AT MICROGRAVITY AND PLANETARY ENVIRONMENTS

Kumar, A.; Dikshit, R.; Gupta, N.; Jain, A.; Dey, A.; Nandi, A.; Venugopal, I.; Viswanathan, K.; Sridhara, N.; Rajendra, A.

10.1101/2020.01.22.914853 — bioengineering — Posted on 2020-01-27

816 Characterizing and inferring quantitative cell cycle phase in single-cell RNA-seq data analysis

Hsiao, C. J.; Tung, P.; Blischak, J. D.; Burnett, J.; Barr, K. A.; Dey, K. K.; Stephens, M.; Gilad, Y.

10.1101/526848 — genomics — Posted on 2020-01-27

817 Robustness testing and scalability of phosphate regulated promoters useful for two-stage autoinduction in E. coli

Moreb, E. A.; Ye, Z.; Efromson, J. P.; Hennigan, J. N.; Menacho-Melgar, R.; Lynch, M. D.

10.1101/2020.01.26.920280 — synthetic biology — Posted on 2020-01-26

818 Terminating contamination: large-scale search identifies more than 2,000,000 contaminated entries in GenBank

Steinegger, M.; Salzberg, S. L.

10.1101/2020.01.26.920173 — bioinformatics — Posted on 2020-01-26

819 Non-invasive red-light optogenetic control of Drosophila cardiac function

Men, J.; Li, A.; Jerwick, J.; Li, Z.; Tanzi, R.; Zhou, C.

10.1101/2020.01.26.920132 — bioengineering — Posted on 2020-01-26

820 CCSN: Single Cell RNA Sequencing Data Analysis by Conditional Cell-specific Network

Li, L.; Dai, H.; Fang, Z.; Chen, L.

10.1101/2020.01.25.919829 — bioinformatics — Posted on 2020-01-26

821 The Power of Citizen Science to Quantify Ecological Risks in Cities

Putman, B. J.; Williams, R.; Li, E.; Pauly, G. B.

10.1101/2020.01.26.920124 — ecology — Posted on 2020-01-26

822 CSF1R inhibition by a small molecule inhibitor affects hematopoiesis and the function of macrophages.

Lei, F.; Cui, N.; Zhou, C.; Chodosh, J.; Vavvas, D. G.; Paschalis, E. I.

10.1101/2019.12.27.889469 — neuroscience — Posted on 2020-01-26

823 Design of a biosensor for direct visualisation of auxin

Herud-Sikimic, O.; Stiel, A. C.; Ortega-Perez, M.; Shanmugaratnam, S.; Hoecker, B.; Juergens, G. C.

10.1101/2020.01.19.911735 — plant biology — Posted on 2020-01-26

824 Extended access self-administration of methamphetamine is associated with age- and sex-dependent differences in drug taking behavior and recognition memory deficits in rats

Westbrook, S. R.; Dwyer, M. R.; Cortes, L. R.; Gulley, J. M.

10.1101/850396 — neuroscience — Posted on 2020-01-26

825 The role of vegetative cell fusions in the lifestyle of the wheat fungal pathogen Zymoseptoria tritici

Francisco, C. S.; Zwyssig, M. M.; Palma-Guerrero, J.

10.1101/2020.01.26.918797 — cell biology — Posted on 2020-01-26

826 Cryptogams signify key transition of bacteria and fungi in Arctic sand dune succession

Juottonen, H.; Mannisto, M.; Tiirola, M.; Kytoviita, M.-M.

10.1101/699876 — ecology — Posted on 2020-01-26

827 Targeting the oncogene LSF with either the small molecule inhibitor FQI1 or siRNA causes mitotic delays with unaligned chromosomes, resulting in cell death or senescence

Willoughby, J. L. S.; George, K.; Roberto, M. P.; Chin, H. G.; Stoiber, P.; Shin, H.; Pedamallu, C. S.; Schaus, S. E.; Fitzgerald, K.; Shah, J.; Hansen, U.

10.1101/665570 — cancer biology — Posted on 2020-01-26

828 Origin time and epidemic dynamics of the 2019 novel coronavirus

Zhang, C.; Wang, M.

10.1101/2020.01.25.919688 — microbiology — Posted on 2020-01-26

829 Transmission dynamics of 2019 novel coronavirus (2019-nCoV)

Liu, T.; Hu, J.; Kang, M.; Lin, L.; Zhong, H.; Xiao, J.; He, G.; Song, T.; Huang, Q.; Rong, Z.; Deng, A.; Zeng, W.; Tan, X.; Zeng, S.; Zhu, Z.; Li, J.; Wan, D.; Lu, J.; Deng, H.; He, J.; Ma, W.

10.1101/2020.01.25.919787 — systems biology — Posted on 2020-01-26

830 Investigating resting brain perfusion abnormalities and target-engagement by intranasal oxytocin in women with bulimia nervosa and binge-eating disorder and healthy controls

Martins, D.; Leslie, M.; Rodan, S.; Zelaya, F.; Treasure, J.; Paloyelis, Y.

10.1101/2020.01.26.920090 — neuroscience — Posted on 2020-01-26

831 Generation of cell-free matrices that support human NK cell migration and differentiation

Lee, B. J.; Mace, E. M.

10.1101/2020.01.26.920116 — cell biology — Posted on 2020-01-26

832 Taxane induces attenuation of the CXCR2/BCL-2 axis and sensitize prostate cancer to platinum-based treatments

Ruiz de Porras, V.; Wang, X. C.; Palomero, L.; Marin-Aguilera, M.; Indacochea, A.; Jimenez, N.; Mellado, B.; Bystrup, S.; Sole-Blanch, C.; Piulats, J. M.; Suarez, J. F.; Pardo, J. C.; Martinez-Balibrea, E.; Aytes, A.; Font, A.

10.1101/2020.01.20.912824 — cancer biology — Posted on 2020-01-26

833 Interleukin-11 is a Marker for Both Cancer- and Inflammation-Associated Fibroblasts that Contribute to Colorectal Cancer Progression

Nishina, T.; Deguchi, Y.; Takeda, W.; Ohtsuka, M.; Ohshima, D.; Yamazaki, S.; Kawauchi, M.; Nakamura, E.; Nishiyama, C.; Kojima, Y.; Adachi-Akemi, S.; Hasegawa, M.; Nakayama, M.; Ohshima, M.; Yagita, H.; Shibuya, K.; Mikami, T.; Inohara, N.; Tada, N.; Nakano, H.

10.1101/2020.01.25.919795 — cancer biology — Posted on 2020-01-26

834 A critical role for MSI1 and MSI2 in photoreceptor morphogenesis

Sundar, J.; Matalkah, F.; Jeong, B.; Stoilov, P.; Ramamurthy, V.

10.1101/2020.01.25.919761 — developmental biology — Posted on 2020-01-26

835 Stoichiometric Analysis of Protein Complexes by Cell Fusion and Single Molecule Imaging

Singh, A.; Van Slyke, A.; Sirenko, M.; Song, A.; Kammermeier, P.; Zipfel, W.

10.1101/2020.01.26.920058 — biophysics — Posted on 2020-01-26

836 An Autoencoder and Artificial Neural Network-based Method to Estimate Parity Status of Wild Mosquitoes from Near-infrared Spectra

Milali, M. P.; Kiware, S. S.; Govella, N. J.; Okumu, F.; Bansal, N.; Bozdag, S.; Charlwood, J. D.; Maia, M. F.; Ogoma, S. B.; Dowell, F. E.; Corliss, G. F.; Sikulu-Lord, M. T.; Povinelli, R. J.

10.1101/2020.01.25.919878 — bioinformatics — Posted on 2020-01-26

837 TMEM184B controls pruriceptor specification and function

Larsen, E. G.; Cho, T. S.; McBride, M. L.; Feng, J.; Manivannan, B.; Madura, C.; Klein, N. E.; Wright, E. B.; Garcia-Verdugo, H. D.; Jarvis, C.; Khanna, R.; Hu, H.; Largent-Milnes, T. M.; Bhattacharya, M. R. C.

10.1101/2020.01.25.919902 — neuroscience — Posted on 2020-01-26

838 Conservation genomics of an Australian orchid complex with implications for the taxonomic and conservation status of Corybas dowlingii

Wagner, N. D.; Clements, M. A.; Simpson, L.; Nargar, K.

10.1101/2020.01.22.916080 — genetics — Posted on 2020-01-26

839 SCANNER: A Web Server for Annotation, Visualization and Sharing of Single Cell RNA-seq Data

Cai, G.; Xiao, F.

10.1101/2020.01.25.919712 — bioinformatics — Posted on 2020-01-26

840 Epigenetic engineering of yeast reveals dynamic molecular adaptation to methylation stress and genetic modulators of specific DNMT3 family members

Finnegan, A. I.; Kim, S.; Jin, H.; Gapinske, M.; Woods, W.; Perez-Pinera, P.; Song, J. S.

10.1101/2020.01.26.919936 — genomics — Posted on 2020-01-26

841 Quantitative and molecular differences distinguish adult human medullary and extramedullary haematopoietic stem and progenitor cell landscapes

Mende, N.; Bastos, H.; Santoro, A.; Sham, K.; Mahbubani, K. T.; Curd, A.; Takizawa, H.; Wilson, N. K.; Gottgens, B.; Saeb-Parsy, K.; Laurenti, E.

10.1101/2020.01.26.919753 — cell biology — Posted on 2020-01-26

842 Phase transition of prion protein initiates proteinase K resistant amyloid formation

Tange, H.; Ishibashi, D.; Nakagaki, T.; Taguchi, Y.; Kamatari, Y. O.; Nishida, N.; Ozawa, H.

10.1101/2020.01.25.919340 — biochemistry — Posted on 2020-01-26

843 MISTR: A conserved MItochondrial STress Response network revealed by signatures of evolutionary conflict

Sorouri, M.; Chang, T.; Jesudhasan, P.; Pinkham, C.; Elde, N. C.; Hancks, D.

10.1101/2020.01.25.919811 — genetics — Posted on 2020-01-26

844 Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-nCov

Zhao, Y.; Zhao, Z.; Wang, Y.; Zhou, Y.; Ma, Y.; Zuo, W.

10.1101/2020.01.26.919985 — bioinformatics — Posted on 2020-01-26

845 SBOL Visual 2 Ontology

Misirli, G.; Beal, J.; Gorochowski, T. E.; Stan, G.-B.; Wipat, A.; Myers, C.

10.1101/2020.01.24.918417 — synthetic biology — Posted on 2020-01-26

846 Completion and augmentation of connectomic datasets in dementia and Alzheimer's Disease using Virtual Patient Cohorts

Arbabyazd, D. M.; Shen, K.; Wang, Z.; Hofmann-Apitius, M.; McIntosh, A. R.; Battaglia, D.; Jirsa, V.

10.1101/2020.01.18.911248 — neuroscience — Posted on 2020-01-26

847 Spherical deconvolution with tissue-specific response functions and multi-shell diffusion MRI to estimate multiple fiber orientation distributions (mFODs)

De Luca, A.; Guo, F.; Froeling, M.; Leemans, A.

10.1101/739136 — bioinformatics — Posted on 2020-01-26

848 Patterns of socio-cognitive stratification and perinatal risk in the child brain

Alnaes, D.; Kaufmann, T.; Marquand, A. F.; Smith, S. M.; Westlye, L. T.

10.1101/839969 — neuroscience — Posted on 2020-01-26

849 Modular slowing of resting-state dynamic Functional Connectivity as a marker of cognitive dysfunction induced by sleep deprivation

Lombardo, D.; Casse-Perrot, C.; Ranjeva, J.-P.; Le Troter, A.; Guye, M.; Wirsich, J.; Payoux, P.; Bartres-Faz, D.; Bordet, R.; Richardson, J. C.; Felician, O.; Jirsa, V.; Blin, O.; Didic, M.; Battaglia, D.

10.1101/2020.01.17.910810 — neuroscience — Posted on 2020-01-26

850 Mechanical stretch sustains myofibroblast phenotype and function in microtissues through latent TGF-β1 activation

Walker, M.; Godin, M.; Pelling, A.

10.1101/2020.01.25.917179 — cell biology — Posted on 2020-01-26

851 Time dependencies in the dynamic mechanical behavior of 3D microtissue cell cultures

Walker, M.; Godin, M.; Harden, J.; Pelling, A.

10.1101/2020.01.25.916874 — biophysics — Posted on 2020-01-26

852 Cerebellar lesions disrupt spatial and temporal visual attention.

Craig, B. T.; Morrill, A.; Anderson, B.; Danckert, J.; Striemer, C. L.

10.1101/822635 — neuroscience — Posted on 2020-01-26

853 The intrinsic neonatal hippocampal network: rsfMRI findings

Howell, A. L.; Osher, D. E.; Li, J.; Saygin, Z. M.

10.1101/823500 — neuroscience — Posted on 2020-01-26

854 Deficiency of Norepinephrine Transmission In Brain Contributed To Seizure-Induced Respiratory Arrest In the DBA/1 Mouse SUDEP Model

Shen, Y.; MA, H.; Lu, H.; Zhao, H.; Sun, J.; Cheng, Y.; Shen, Y.; Zhou, Y. D.; Zhang, H.

10.1101/865691 — neuroscience — Posted on 2020-01-26

855 A universal chromosome identification system for maize and wild Zea species

Tomaz Braz, G.; do Vale Martins, L.; Zhang, T.; S. Albert, P.; A. Birchler, J.; Jiang, J.

10.1101/2020.01.22.915942 — genetics — Posted on 2020-01-26

856 From SARS-CoV to Wuhan 2019-nCoV Outbreak: Similarity of Early Epidemic and Prediction of Future Trends

Chen, Z.; Zhang, W.; Lu, Y.; Guo, C.; Guo, Z.; Liao, C.; Zhang, X.; Zhang, Y.; Han, X.; Li, Q.; Lu, J.

10.1101/2020.01.24.919241 — microbiology — Posted on 2020-01-26

857 Exhaustive identification of conserved upstream open reading frames with potential translational regulatory functions from animal genomes

Takahashi, H.; Miyaki, S.; Onouchi, H.; Motomura, T.; Idesako, N.; Takahashi, A.; Murase, M.; Fukuyoshi, S.; Endo, T.; Satou, K.; Naito, S.; Itoh, M.

10.1101/672840 — bioinformatics — Posted on 2020-01-26

858 MHC*IMP - Imputation of Alleles for Genes in the Major Histocompatibility Complex

Squire, D. M.; Motyer, A.; Ahn, R.; Nitiham, J.; Huang, Z.-M.; Oksenberg, J. R.; Foerster, J.; Liao, W.; Leslie, S.

10.1101/2020.01.24.919191 — genomics — Posted on 2020-01-26

859 Distribution of genetic diversity reveals colonization and philopatry of the loggerhead sea turtles across geographic scales

Baltazar-Soares, M.; Klein, J. L.; Correia, S. M.; Reischig, T.; Taxonera, A. A.; Monteiro, S. R.; Dos Passos, L.; Jandira, D.; Lomba, J. P.; Dinis, H.; Cameron, S. J. K.; Stiebens, V. A.; Eizaguirre, C.

10.1101/2020.01.23.916866 — evolutionary biology — Posted on 2020-01-26

860 Discovery of the spatial pattern of prickles on the stem of the rose and the mathematical model of the pattern.

Amikura, K.; Ito, H.

10.1101/811281 — developmental biology — Posted on 2020-01-26

861 Identification of flavone and its derivatives as potential inhibitors of transcriptional regulator LasR of Pseudomonas aeruginosa using virtual screening

Abelyan, N. N.; Grabski, H.; Tiratsuyan, S.

10.1101/523381 — bioinformatics — Posted on 2020-01-26

862 Skp1 Dimerization Conceals its F-box Protein Binding Site

Kim, H. W.; Eletsky, A.; Gonzalez, K. J.; van der Wel, H.; Strauch, E.-M.; Prestegard, J. H.; West, C. M.

10.1101/764126 — biochemistry — Posted on 2020-01-26

863 Systems Biomedicine of Colorectal Cancer Reveals Potential Targets for CRC treatment

Piran, M.; Piran, M.; Sepahi, N.; Rahimi, A.

10.1101/2020.01.25.919415 — systems biology — Posted on 2020-01-25

864 Calsyntenin-3 directly interacts with neurexins to orchestrate excitatory synapse development in the hippocampus

Kim, H.; Kim, D.; Kim, J.; Lee, H.-Y.; Park, D.; Kang, H.; Matsuda, K.; Sterky, F. H.; Yuzaki, M.; Kim, J. Y.; Choi, S.-Y.; Ko, J.; Um, J. W.

10.1101/2020.01.24.918722 — neuroscience — Posted on 2020-01-25

865 Ensemble perception in the time domain: evidence in favor of logarithmic encoding of time intervals

Ren, Y.; Müller, H. J.; Shi, Z.

10.1101/2020.01.25.919407 — neuroscience — Posted on 2020-01-25

866 Community sequencing on a natural experiment reveals little influence of host species and timing but a strong influence of compartment on the composition of root endophytes in three annual Brassicaceae

Macia-Vicente, J. G.; Nam, B.; Thines, M.

10.1101/2020.01.24.918177 — microbiology — Posted on 2020-01-25

867 Systematic and functional analysis of horizontal gene transfer events in diatoms.

Vancaester, E.; Osuna-Cruz, C. M.; Depuydt, T.; Vandepoele, K.

10.1101/2020.01.24.918219 — evolutionary biology — Posted on 2020-01-25

868 Convergent stress response repertoire to thermal challenges in a temperate aposymbiotic coral

Wuitchik, D. M.; Almanzar, A.; Benson, B. E.; Brennan, S. A.; Chavez, J. D.; Liesegang, M. B.; Reavis, J. L.; Reyes, C. L.; Schniedewind, M. K.; Trumble, I. F.; Davies, S. W.

10.1101/2020.01.25.919399 — ecology — Posted on 2020-01-25

869 Cross-sectional and longitudinal associations of family income-to-needs ratio with cortical and subcortical brain volume in adolescent boys and girls

King, L. S.; Dennis, E. L.; Humphreys, K. L.; Thompson, P. M.; Gotlib, I. H.

10.1101/2020.01.24.918847 — developmental biology — Posted on 2020-01-25

870 A paleogenetic perspective of the Sabana de Bogota (Northern South America) population history over the Holocene (9000 - 550 cal BP)

Delgado, M. E.; Rodriguez, F.; Kassadjikova, K.; Fehren Schmitz, L.

10.1101/2020.01.24.918425 — genetics — Posted on 2020-01-25

871 Novel function acquired by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals

Martin-Martin, I.; Paige, A.; Valenzuela-Leon, P. C.; Gittis, A.; Kern, O.; Bonilla, B.; Chagas, A. C.; Ganesan, S.; Garboczi, D.; Calvo, E.

10.1101/2020.01.24.918581 — biochemistry — Posted on 2020-01-25

872 A comprehensive atlas of white matter tracts in the chimpanzee

Bryant, K. L.; Li, L.; Mars, R. B.

10.1101/2020.01.24.918516 — neuroscience — Posted on 2020-01-25

873 Evolution and maintenance of microbe-mediated protection under occasional pathogen attack

Kloock, A.; Bonsall, M.; King, K.

10.1101/2020.01.24.917138 — microbiology — Posted on 2020-01-25

874 One cell, one drop, one click: hybrid microfluidic mammalian single-cell isolation

Samlali, K.; Ahmadi, F.; Quach, A. B. V.; Soffer, G.; Shih, S. C. C.

10.1101/2020.01.24.908202 — bioengineering — Posted on 2020-01-25

875 New distribution records and range extensions of mosquitoes in British Columbia and the Yukon Territory

Peach, D. A.; Poirier, L. M.

10.1101/2020.01.24.919233 — zoology — Posted on 2020-01-25

876 A theory of the use of information by enemies in the predator-prey space race

Patin, R.; Fortin, D.; Chamaille-Jammes, S.

10.1101/2020.01.25.919324 — animal behavior and cognition — Posted on 2020-01-25

877 Cold tolerance in rice plants is partially controlled by root responses

Rativa, A. G. S.; Junior, A. T. d. A.; Friedrich, D. d. S.; Gastmann, R.; Lamb, T. I.; de Vargas, I.; Silva, A. d. S.; Pozzebon-Silva, A.; Adamski, J. M.; Fett, J. P.; Ricachenevsky, F. K.; Sperotto, R. A.

10.1101/2020.01.25.919464 — plant biology — Posted on 2020-01-25

878 Gut Microbiota Mediates the Protective Effects of Andrographolide Inhibits Inflammation and Nonalcoholic Fatty Liver Disease(NAFLD) in High-Fat Diet induced ApoE(-/-) Mice

Shi, S.; Ji, X. Y.; Shi, J. J.; Shi, S. Q.; Jia, Q. L.; Yuan, G. Z.; Zhang, Q. Y.; Dong, Y.; Lu, Y. D.; Cui, H. M.; Hu, Y. H.

10.1101/2020.01.24.919316 — pharmacology and toxicology — Posted on 2020-01-25

879 Memory deficits following hippocampal versus parahippocampal damage double-dissociate according to both process and material type

Argyropoulos, G. P. D.; Dell'Acqua, C.; Butler, E.; Loane, C.; Roca-Fernandez, A.; Almozel, A.; Drummond, N.; Lage-Martinez, C.; Cooper, E.; Henson, R. N.; Butler, C. R.

10.1101/2020.01.25.919423 — neuroscience — Posted on 2020-01-25

880 Flexible contextual modulation of naturalistic texture perception in peripheral vision

Herrera, D.; Coen-Cagli, R.; Gomez-Sena, L.

10.1101/2020.01.24.918813 — neuroscience — Posted on 2020-01-25

881 Improvement of glymphatic-lymphatic drainage of beta-amyloid by focused ultrasound in Alzheimer's disease model

Lee, Y.; Choi, Y.; Park, E.-J.; Kwon, S.; Kim, H.; Lee, J. Y.; Lee, D. S.

10.1101/2020.01.24.918607 — neuroscience — Posted on 2020-01-25

882 Heterozygous mutation of Sonic Hedgehog receptor (Ptch) drives cerebellar overgrowth and sex-specifically alters hippocampal and cortical layer structure, activity, and social behavior in female mice

Jackson, T. W.; Bendfeldt, G. A.; Beam, K. A.; Rock, K. D.; Belcher, S. M.

10.1101/2020.01.25.919506 — neuroscience — Posted on 2020-01-25

883 A neural correlate of visual discomfort from flicker

Patterson Gentile, C.; Aguirre, G. K.

10.1101/2020.01.25.919472 — neuroscience — Posted on 2020-01-25

884 Neurons in Visual Cortex are Driven by Feedback Projections when their Feedforward Sensory Input is Missing

Keller, A. J.; Roth, M. M.; Scanziani, M.

10.1101/2020.01.24.919142 — neuroscience — Posted on 2020-01-25

885 Differential processing and habituation in distinct spatial frequency channels in V1 of a mouse model of fragile X syndrome

Pak, A.; Kissinger, S. T.; Chubykin, A. A.

10.1101/2020.01.24.919035 — neuroscience — Posted on 2020-01-25

886 BAcTrace a new tool for retrograde tracing of neuronal circuits

Cachero, S.; Gkantia, M.; Bates, A. S.; Frechter, S.; Blackie, L.; Mccarthy, A.; Sutcliffe, B.; Strano, A.; Aso, Y.; Jefferis, G. S. X. E.

10.1101/2020.01.24.918656 — neuroscience — Posted on 2020-01-25

887 Human stem cell derived sensory neurons are positioned to support varicella zoster virus latency

Sadaoka, T.; Rajbhandari, L.; Shukla, P.; Jagdish, B.; Lee, H.; Lee, G.; Venkatesan, A.

10.1101/2020.01.24.919290 — microbiology — Posted on 2020-01-25

888 The Arabidopsis "retrovirome" and its regulation by epigenetically activated small RNA

Lee, S. C.; Ernst, E.; Berube, B.; Borges, F.; Schorn, A.; Parent, J.-S.; Ledon, P.; Martienssen, R. A.

10.1101/2020.01.24.919167 — genomics — Posted on 2020-01-25

889 Effect of short-term prescription opioids on DNA methylation of the OPRM1 promoter

Sandoval-Sierra, J. V.; García, F. I. S.; Brooks, J. H.; Derefinko, K. J.; Mozhui, K.

10.1101/2020.01.24.919084 — genomics — Posted on 2020-01-25

890 Evaluation of Genetic Diversity in Cultivated and Exotic Germplasm Sources of Faba Bean Using Important Morphological Traits

Kumar, P.; Kaushik, P.

10.1101/2020.01.24.918284 — genetics — Posted on 2020-01-25

891 Single generation exposure to a captive diet: a primer for domestication selection in a salmonid fish?

Islam, S. S.; Yates, M. C.; Fraser, D. J.

10.1101/2020.01.24.919175 — evolutionary biology — Posted on 2020-01-25

892 Finding A Fresh Carcass: Bacterially-Derived Volatiles And Burying Beetle Search Success

Trumbo, S. T.; Steiger, S.

10.1101/2020.01.25.919696 — ecology — Posted on 2020-01-25

893 Patterns of selection against centrosome amplification in human cell lines

Dias Louro, M. A.; Bettencourt-Dias, M.; Bank, C.

10.1101/2020.01.24.918615 — cell biology — Posted on 2020-01-25

894 Extending rnaSPAdes functionality for hybridtranscriptome assembly

Prjibelski, A. D.; Puglia, G. D.; Antipov, D.; Bushmanova, E.; Giordano, D.; Mikheenko, A.; Vitale, D.; Lapidus, A.

10.1101/2020.01.24.918482 — bioinformatics — Posted on 2020-01-25

895 Splice-specific deficiency of the PTSD-associated gene PAC1 leads to a paradoxical age-dependent stress behavior

Biran, J.; Gliksberg, M.; Shirat, I.; Swaminathan, A.; Levitas-Djerbi, T.; Appelbaum, L.; Levkowitz, G.

10.1101/2020.01.24.918185 — animal behavior and cognition — Posted on 2020-01-25

896 Functional diversity metrics using kernel density n-dimensional hypervolumes

Mammola, S.; Cardoso, P.

10.1101/2020.01.25.919373 — ecology — Posted on 2020-01-25

897 Transcription factor enrichment analysis (TFEA): Quantifying the activity of hundreds of transcription factors from a single experiment

Rubin, J. D.; Stanley, J. T.; Sigauke, R. F.; Levandowski, C. B.; Maas, Z. L.; Westfall, J.; Taatjes, D. J.; Dowell, R. D.

10.1101/2020.01.25.919738 — bioinformatics — Posted on 2020-01-25

898 Captive-reared migratory monarch butterflies show natural orientation when released in the wild

Wilcox, A. A. E.; Newman, A. E. M.; Raine, N. E.; Norris, D. R.

10.1101/2020.01.24.919027 — ecology — Posted on 2020-01-25

899 Differentiating between integration and non-integration strategies in perceptual decision making

Stine, G. M.; Zylberberg, A.; Ditterich, J.; Shadlen, M. N.

10.1101/2020.01.24.918169 — neuroscience — Posted on 2020-01-25

900 Competition sensing alters antibiotic production in Streptomyces

Westhoff, S.; Kloosterman, A.; van Hoesel, S. F. A.; van Wezel, G. P.; Rozen, D. E.

10.1101/2020.01.24.918557 — microbiology — Posted on 2020-01-25

901 Restricted sequence variation in Streptococcus pyogenes penicillin binding proteins

Hayes, A.; Lacey, J. A.; Morris, J.; Davies, M. R.; Tong, S. Y. C.

10.1101/2020.01.24.919308 — microbiology — Posted on 2020-01-25

902 Chlorotoxin Redirects Chimeric Antigen Receptor T Cells for Specific and Effective Targeting of Glioblastoma

Wang, D.; Starr, R.; Chang, W.-C.; Aguilar, B.; Alizadeh, D.; Wright, S. L.; Yang, X.; Brito, A.; Sarkissian, A.; Ostberg, J. R.; Shi, Y.; Gutova, M.; Aboody, K.; Badie, B.; Forman, S. J.; Barish, M.; Brown, C.

10.1101/2020.01.24.918888 — immunology — Posted on 2020-01-25

903 Ecology and evolutionary history determine plastic responses to environmental variation in two closely related species

Walter, G. M.; Clark, J.; Cristaudo, A.; Nevado, B.; Catara, S.; Paunov, M.; Velikova, V.; Filatov, D.; Cozzolino, S.; Hiscock, S.; Bridle, J. R.

10.1101/2020.01.24.918201 — evolutionary biology — Posted on 2020-01-25

904 Evidence for a growing population of eastern migratory monarch butterflies is currently insufficient (with extinction risk analyses)

Thogmartin, W. E.; Szymanski, J. A.; Weiser, E. L.

10.1101/2020.01.24.918649 — ecology — Posted on 2020-01-25

905 The Wg and Dpp morphogens regulate gene expression by modulating the frequency of transcriptional bursts

Bakker, R.; Mani, M.; Carthew, R. W.

10.1101/2020.01.24.918623 — developmental biology — Posted on 2020-01-25

906 A susceptibility locus on chromosome 13 profoundly impacts the stability of genomic imprinting in mouse pluripotent stem cells

Swanzey, E.; McNamara, T. F.; Apostolou, E.; Tahiliani, M.; Stadtfeld, M.

10.1101/2020.01.25.915413 — cell biology — Posted on 2020-01-25

907 A biomimetic five-module chimeric antigen receptor (5MCAR) designed to target and eliminate antigen-specific T cells

Kobayashi, S.; Thelin, M. A.; Parrish, H. L.; Deshpande, N. R.; Lee, M. S.; Karimzadeh, A.; Niewczas, M. A.; Serwold, T.; Kuhns, M. S.

10.1101/2020.01.24.916932 — bioengineering — Posted on 2020-01-25

908 Edaravone-Loaded Mesoscale Nanoparticles Treat Cisplatin-Induced Acute Kidney Injury

Williams, R. M.; Shah, J.; Mercer, E.; Tian, H. S.; Cheung, J. M.; Dorso, M.; Jaimes, E. A.; Heller, D. A.

10.1101/2020.01.24.919134 — bioengineering — Posted on 2020-01-25

909 Time varying connectivity across the brain changes as a function of nicotine abstinence state

Fedota, J. R.; Ross, T. J.; Castillo, J.; McKenna, M. R.; Matous, A. L.; Salmeron, B. J.; Menon, V.; Stein, E. A.

10.1101/2020.01.25.917617 — animal behavior and cognition — Posted on 2020-01-25

910 Aphid feeding induces the relaxation of epigenetic control and the associated regulation of the defense response in Arabidopsis

Annacondia, M. L.; Markovic, D.; Reig-Valiente, J. L.; Scaltsoyiannes, V.; Pieterse, C. M. J.; Ninkovic, V.; Slotkin, R. K.; Martinez, G.

10.1101/2020.01.24.916783 — plant biology — Posted on 2020-01-25

911 Early life stress reduces voluntary exercise and its prevention of diet-induced obesity and metabolic dysfunction in mice

Eller-Smith, O. C.; Morris, E. M. M.; Thyfault, J. P.; Christianson, J. A.

10.1101/2020.01.24.918805 — physiology — Posted on 2020-01-25

912 Reliability of dynamic network reconfiguration: Impact of code implementation, parameter selection, scan duration, and task condition

Yang, Z.; Telesford, Q. K.; Franco, A. R.; Gu, S.; Xu, T.; Ai, L.; Lim, R.; Castellanos, F. X.; Yan, C.-G.; Bassett, D. S.; Colcombe, S.; Milham, M. P.

10.1101/2020.01.24.914622 — neuroscience — Posted on 2020-01-25

913 Involuntary orienting and conflict resolution during auditory attention: The role of ventral and dorsal streams

Stewart, H. J.; Shen, D.; Sham, N.; Alain, C.

10.1101/2020.01.24.917310 — neuroscience — Posted on 2020-01-25

914 Characterization of a novel NDM-5-harboring plasmid from a carbapenem-resistant Escherichia coli isolate from China

Yin, D.; Lin, Y.; Li, Z.; Ma, H.; Lu, L.; Wang, K.; Yang, L.; Du, X.; Song, H.; Li, P.; Qi, K.

10.1101/2020.01.24.919274 — genomics — Posted on 2020-01-25

915 A Synergism Between Dimethyl Trisulfide And Methyl Thiolacetate In Attracting Carrion-Frequenting Beetles Demonstrated By Use Of A Chemically-Supplemented Minimal Trap

Trumbo, S. T.; Dicapua, J. A.

10.1101/2020.01.25.919670 — ecology — Posted on 2020-01-25

916 Variation in root secondary metabolites is shaped by past climatic conditions

Bont, Z.; Zuest, T.; Huber, M.; Erb, M.

10.1101/2020.01.25.919654 — ecology — Posted on 2020-01-25

917 Hydropathy patterning complements charge patterning to describe conformational preferences of disordered proteins

Zheng, W.; Dignon, G. L.; Brown, M.; Kim, Y. C.; Mittal, J.

10.1101/2020.01.25.919498 — biophysics — Posted on 2020-01-25

918 Pathway Mining and Data Mining in Functional Genomics. An Integrative Approach to Delineate Boolean Relationships Between Src and Its targets

Piran, M.; Fernandes, P. L.; Sepahi, N.; Piran, M.; Rahimi, A.

10.1101/2020.01.25.919639 — bioinformatics — Posted on 2020-01-25

919 New candidates for regulated gene integrity revealed through precise mapping of integrative genetic elements

Mageeney, C. M.; Lau, B. Y.; Wagner, J. M.; Hudson, C. M.; Schoeniger, J. S.; Krishnakumar, R.; Williams, K. P.

10.1101/2020.01.24.918748 — bioinformatics — Posted on 2020-01-25

920 SBOL Visual 2 Ontology

Misirli, G.; Beal, J.; Gorochowski, T.; Stan, G.-B.; Wipat, A.; Myers, C.

10.1101/2020.01.24.918417 — synthetic biology — Posted on 2020-01-25

921 Characterizing expression of candidate genes of a glutamate receptor pathway in Arabidopsis thaliana using real-time RT-PCR

Wurdeman, J.; Durham Brooks, T.

10.1101/2020.01.24.918599 — plant biology — Posted on 2020-01-25

922 AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication

Yamashiro, K.; Hori, K.; Lai, E. S. K.; Aoki, R.; Shimaoka, K.; Egusa, S. F.; Sakamoto, A.; Abe, M.; Sakimura, K.; Watanabe, T.; Uesaka, N.; Kano, M.; Hoshino, M.

10.1101/2020.01.24.917989 — neuroscience — Posted on 2020-01-25

923 Asymmetric transcallosal conduction delay leads to finer bimanual coordination

Bortoletto, M.; Bonzano, L.; Zazio, A.; Pedulla, L.; Gasparotti, R.; Miniussi, C.; Bove, M.

10.1101/2020.01.24.918102 — neuroscience — Posted on 2020-01-25

924 Pharmacological depletion of microglia prevents vascular cognitive impairment in Ang II-induced hypertension

Kerkhofs, D.; Hagen, B. v.; Milanova, I. V.; Schell, K.; Essen, H. v.; Wijnands, E.; Goossens, P.; Blankesteijn, W. M.; Unger, T.; Prickaerts, J.; Biessen, E. A.; Oostenbrugge, R. J. v.; Foulquier, S.

10.1101/2020.01.24.916650 — neuroscience — Posted on 2020-01-25

925 Metastable attractors explain the variable timing of stable behavioral action sequences

Recanatesi, S.; Pereira Obilinovic, U.; Murakami, M.; Mainen, Z.; Mazzucato, L.

10.1101/2020.01.24.919217 — neuroscience — Posted on 2020-01-25

926 Proteomic changes in bacteria caused by exposure to environmental conditions can be detected by Matrix-Assisted Laser Desorption/Ionization - Time of Flight (MALDI-ToF) Mass Spectrometry

Chac, D.; Kordahi, M.; Brettner, L.; Verma, A.; McCleary, P.; Crebs, K.; Yee, C.; DePaolo, R. W.

10.1101/2020.01.24.918938 — microbiology — Posted on 2020-01-25

927 Profiling the microbial community structure and functional diversity of a dam-regulated river undergoing gravel bar restoration

Serrana, J. M.; Li, B.; Sumi, T.; Takemon, Y.; Watanabe, K.

10.1101/2020.01.25.919381 — microbiology — Posted on 2020-01-25

928 Recombinant protein production and purification of SiiD, SiiE and SiiF - components of the SPI4-encoded type I secretion system from Salmonella Typhimurium

Klingl, S.; Kordes, S.; Schmid, B.; Gerlach, R. G.; Hensel, M.; Muller, Y.

10.1101/2020.01.25.919720 — microbiology — Posted on 2020-01-25

929 Polyamine Metabolism Regulates the T Cell Epigenome Through Hypusination

Puleston, D. J.; Baixauli, F.; Sanin, D. E.; Villa, M.; Kabat, A.; Kaminski, M. M.; Weiss, H.; Grzes, K.; Flachsmann, L. J.; Field, C. S.; Stanckzak, M.; Schimmelpfennig, L.; Hassler, F.; Wang, C.; Yosef, N.; Kuchroo, V. K.; Musa, Y.; Mittler, G.; Buescher, J. M.; Balabanov, S.; Pearce, E. J.; Green, D. R.; Pearce, E. L.

10.1101/2020.01.24.918094 — immunology — Posted on 2020-01-25

930 Luciferase Immunoprecipitation Systems immunoassay is a sensitive, rapid method to detect allergen component-specific IgE

Lin, A.; Perez, N.; Frischmeyer-Guerrerio, P.; Nutman, T.

10.1101/2020.01.24.917153 — immunology — Posted on 2020-01-25

931 MHC*IMP - Imputation of Alleles for Genes in the Major Histocompatibility Complex

Squire, D. M.; Motyer, A.; Ahn, R. S.; Nitiham, J.; Huang, Z.-M.; Oksenberg, J. R.; Liao, W.; Leslie, S.

10.1101/2020.01.24.919191 — genomics — Posted on 2020-01-25

932 Bayesian copy number detection and association in large-scale studies

Cristiano, S.; McKean, D.; Carey, J.; Bracci, P.; Brennan, P.; Chou, M.; Du, M.; Gallinger, S.; Goggins, M. G.; Hassan, M.; Hung, R.; Kurtz, R.; Li, D.; Lu, L.; Neale, R.; Olson, S.; Petersen, G.; Rabe, K.; Fu, J.; Risch, H.; Rosner, G.; Ruczinski, I.; Klein, A. P.; Scharpf, R. B.

10.1101/2020.01.24.918672 — genetics — Posted on 2020-01-25

933 Decoupling of resistance and tolerance against one of two related parasites (Eimeria) in mice

Balard, A.; Jarquin-Diaz, V. H.; Jost, J.; Mittne, V.; Boehning, F.; Dureje, L.; Pialek, J.; Heitlinger, E.

10.1101/2020.01.24.918144 — evolutionary biology — Posted on 2020-01-25

934 Model-based detection of whole-genome duplications in a phylogeny

Zwaenepoel, A.; Van de Peer, Y.

10.1101/2020.01.24.917997 — evolutionary biology — Posted on 2020-01-25

935 From individual behavior and pack dynamics to population responses: An individual-based approach to model the wolf social life cycle

Bauduin, S.; Grente, O.; Santostasi, N.; Ciucci, P.; Duchamp, C.; Gimenez, O.

10.1101/2020.01.24.918490 — ecology — Posted on 2020-01-25

936 Atomistic Molecular Dynamics Simulations of Trioleoylglycerol - Phospholipid Membrane Systems

Mirza, A. H.; Akram, H. M.; Raza, M. S.

10.1101/2020.01.25.918136 — biophysics — Posted on 2020-01-25

937 AITL: Adversarial Inductive Transfer Learning with input and output space adaptation for pharmacogenomics

Sharifi Noghabi, H.; Peng, S.; Zolotareva, O.; Collins, C. C.; Ester, M.

10.1101/2020.01.24.918953 — bioinformatics — Posted on 2020-01-25

938 The Effects of Copper Addition on The Structure, and Antibacterial Properties of Biomedical Glasses

Razavi, A.; Mojtabavi, L.

10.1101/2020.01.24.918524 — bioengineering — Posted on 2020-01-25

939 Summary-data-based mendelian randomisation reveals druggable targets for multiple sclerosis

Jacobs, B. M.; Taylor, T.; Awad, A.; Giovannoni, G.; Baker, D.; Noyce, A. J.; Dobson, R.

10.1101/2020.01.20.907451 — genetics — Posted on 2020-01-25

940 Comparison of visualisation tools for single-cell RNAseq data

Cakir, B.; Prete, M.; Huang, N.; van Dongen, S.; Pir, P.; Kiselev, V. Y.

10.1101/2020.01.24.918342 — bioinformatics — Posted on 2020-01-25

941 Complete genome characterisation of a novel coronavirus associated with severe human respiratory disease in Wuhan, China

Wu, F.; Zhao, S.; Yu, B.; Chen, Y.-M.; Wang, W.; Hu, Y.; Song, Z.-G.; Tao, Z.-W.; Tian, J.-H.; Pei, Y.-Y.; Yuan, M.-L.; Zhang, Y.-L.; Dai, F.-H.; Liu, Y.; Wang, Q.-M.; Zheng, J.-J.; Xu, L.; Holmes, E. C.; Zhang, Y.-Z.

10.1101/2020.01.24.919183 — pathology — Posted on 2020-01-25

942 From SARS-CoV to Wuhan 2019-nCoV: Will History Repeat Itself?

Chen, Z.; Zhang, W.; Lu, Y.; Guo, C.; Guo, Z.; Liao, C.; Zhang, X.; Zhang, Y.; Han, X.; Li, Q.; Lipkin, W. I.; Lu, J.

10.1101/2020.01.24.919241 — microbiology — Posted on 2020-01-25

943 Modelling the epidemic trend of the 2019 novel coronavirus outbreak in China

Shen, M.; Peng, Z.; Xiao, Y.; Zhang, L.

10.1101/2020.01.23.916726 — microbiology — Posted on 2020-01-25

944 2019-20 Wuhan coronavirus outbreak: Intense surveillance is vital for preventing sustained transmission in new locations

Thompson, R. N.

10.1101/2020.01.24.919159 — ecology — Posted on 2020-01-25

945 Effects of Ocean Climate on Spatiotemporal Variation in Sea Urchin Settlement and Recruitment

Okamoto, D. K.; Schroeter, S. C.; Reed, D. C.

10.1101/387282 — ecology — Posted on 2020-01-25

946 Link Prediction through Deep Generative Model

Wang, X.-W.; Chen, Y.; Liu, Y.-Y.

10.1101/247577 — bioinformatics — Posted on 2020-01-25

947 Single-color Fluorescence Lifetime Cross-Correlation Spectroscopy in vivo

Stefl, M.; Knop, M.; Herbst, K.; Rübsam, M.; Benda, A.

10.1101/2020.01.23.917435 — cell biology — Posted on 2020-01-25

948 The two zinc fingers in the nucleocapsid domain of the HIV-1 Gag precursor are equivalent for the interaction with the genomic RNA in the cytoplasm, but not for the recruitment of the complexes at the plasma membrane

Bernacchi, S.; Boutant, E.; Bonzi, J.; Anton, H.; Nasim, M. B.; Cathagne, R.; Real, E.; Dujardin, D.; Carl, P.; Didier, P.; Paillart, J.-C.; Marquet, R.; Mely, Y.; de Rocquigny, H.

10.1101/2020.01.24.918508 — biophysics — Posted on 2020-01-25

949 Tumor Neoantigenicity Assessment with CSiN Score Incorporates Clonality and Immunogenicity to Predict Immunotherapy Outcomes

Lu, T.; Wang, S.; Xu, L.; Zhou, Q.; Singla, N.; Gao, J.; Manna, S.; Pop, L.; Xie, Z.; Chen, M.; Luke, J. J.; Brugarolas, J.; Hannan, R.; Wang, T.

10.1101/2020.01.23.917625 — bioinformatics — Posted on 2020-01-25

950 Remodeling of the core leads HIV-1 pre-integration complex in the nucleus of human lymphocytes.

Blanco, G.; Gazi, A.; Monel, B.; Frabetti, S.; Scoca, V.; Mueller, F.; Schwartz, O.; krijnse-locker, J.; Charneau, P.; Di Nunzio, F.

10.1101/2020.01.24.918383 — microbiology — Posted on 2020-01-25

951 Sir2 tempers an intrinsic imbalance in origin licensing efficiency between early and late replicating euchromatin

Hoggard, T.; Müller, C. A.; Nieduszynski, C. A.; Weinreich, M.; Fox, C. A.

10.1101/2020.01.24.918862 — genetics — Posted on 2020-01-25

952 Acetylation-mediated phase control of the nucleolus regulates cellular acetyl-CoA responses

Houston, R.; Sekine, S.; Calderon, M. J.; Seifuddin, F.; Wang, G.; Kawagishi, H.; Malide, D. A.; Li, Y.; Gucek, M.; Pirooznia, M.; Nelson, A. J.; Stokes, M. P.; Stewart-Ornstein, J.; Wendell, S. G.; Watkins, S. C.; Finkel, T.; Sekine, Y.

10.1101/2020.01.24.918706 — cell biology — Posted on 2020-01-25

953 Oligonucleotides can act as superscaffolds that enhance liquid-liquid phase separation of intracellular mixtures

Joseph, J. A.; Espinosa, J. R.; Sanchez-Burgos, I.; Garaizar, A.; Frenkel, D.; Collepardo-Guevara, R.

10.1101/2020.01.24.916858 — biophysics — Posted on 2020-01-25

954 Drag-induced directionality switching of kinesin-5 Cin8 revealed by cluster-motility analysis

Handey, H.; Reithmann, E.; Goldstein-Levitin, A.; Al-Bassam, J.; Frey, E.; Gheber, L.

10.1101/2020.01.24.918714 — biophysics — Posted on 2020-01-25

955 Role of CYP3A5 in modulating androgen receptor signaling and its relevance to African American men with prostate cancer

Gorjala, P.; Goodman, O. B.; Kittles, R. A.; Mitra, R.

10.1101/2020.01.24.918920 — cancer biology — Posted on 2020-01-25

956 Sequential combinations of chemotherapeutic agents with BH3 mimetics to treat rhabdomyosarcoma and avoid resistance.

Alcon, C.; Manzano-Munoz, A.; Prada, E.; Mora, J.; Soriano, A.; Guillen, G.; Roma, J.; Samitier, J.; Villanueva, A.; Montero, J.

10.1101/2020.01.24.918532 — cancer biology — Posted on 2020-01-25

957 Variation in a pleiotropic regulatory module drives evolution of head shape and eye size in Drosophila

Buchberger, E.; Bilen, A.; Ayaz, S.; Salamanca, D.; Matas de las Heras, C.; Niksic, A.; Almudi, I.; Torres-Oliva, M.; Casares, F.; Posnien, N.

10.1101/2020.01.24.918011 — evolutionary biology — Posted on 2020-01-25

958 Design, optimization, and analysis of large DNA and RNA nanostructures through interactive visualization, editing, and molecular simulation

Poppleton, E.; Bohlin, J.; Matthies, M.; Sharma, S.; Zhang, F.; Sulc, P.

10.1101/2020.01.24.917419 — biophysics — Posted on 2020-01-25

959 Information processing in biological molecular machines

Kurzynski, M.; Chelminiak, P.

10.1101/2020.01.24.918367 — biophysics — Posted on 2020-01-25

960 Combining feature selection and shape analysis uncovers precise rules for miRNA regulation in Huntington's disease mice

Megret, L.; Nair, S. S.; Dancourt, J.; Aaronson, J.; Rosinski, J.; Neri, C.

10.1101/2020.01.24.918540 — bioinformatics — Posted on 2020-01-25

961 Low ribosomal RNA genes copy number provoke genomic instability and chromosomal segment duplication events that modify global gene expression and plant-pathogen response

Picart-Picolo, A.; Grob, S.; Picault, N.; Franek, M.; Halter, T.; Maier, T. R.; Llauro, C.; Jobet, E.; Zhang, P.; Vijayapalani, P.; Baum, T. J.; Navarro, L.; Dvorackova, M.; Mirouze, M.; Pontvianne, F.

10.1101/2020.01.24.917823 — plant biology — Posted on 2020-01-25

962 Buildup and bistability in auditory streaming as an evidence accumulation process with saturation

Nguyen, Q.-A.; Rinzel, J.; Curtu, R.

10.1101/2020.01.24.917799 — neuroscience — Posted on 2020-01-25

963 NF90 Modulates Processing of a Subset of Human Pri-miRNAs

Grasso, G.; Higuchi, T.; Barbier, J.; Helsmoortel, M.; Lorenzi, C.; Sanchez, G.; Bello, M.; Ritchie, W.; Sakamoto, S.; Kiernan, R.

10.1101/2020.01.24.916957 — molecular biology — Posted on 2020-01-25

964 Structural insights into the insecticidal Vip3A toxin of Bacillus thuringiensis

Jiang, K.; Zhang, Y.; Chen, Z.; Wu, D.; Cai, J.; Gao, X.

10.1101/2020.01.24.918433 — microbiology — Posted on 2020-01-25

965 Swine ANP32A supports avian influenza virus polymerase

Peacock, T. P.; Swann, O. C.; Staller, E.; Leung, P. B.; Goldhill, D. H.; Zhou, H.; Long, J. S.; Barclay, W. S.

10.1101/2020.01.24.916916 — microbiology — Posted on 2020-01-25

966 PAKC: A novel Panel of HLA class I Antigen presentation machinery Knockout Cells from the same genetic origin

de Waard, A. A.; Verkerk, T.; Jongsma, M. L. M.; Hoefakker, K.; Sethumadhavan, S.; Gerke, C.; Bliss, S.; Janssen, G. M. C.; de Ru, A. H.; Claas, F. H. J.; Mulder, A.; Tampe, R.; van Veelen, P. A.; Halenius, A.; Spaapen, R. M.

10.1101/2020.01.24.917807 — immunology — Posted on 2020-01-25

967 Climate change will drive novel cross-species viral transmission

Carlson, C. J.; Albery, G. F.; Merow, C.; Trisos, C. H.; Zipfel, C. M.; Eskew, E. A.; Olival, K.; Ross, N.; Bansal, S.

10.1101/2020.01.24.918755 — ecology — Posted on 2020-01-25

968 Structure-based inhibitors reveal roles for the clathrin terminal domain and its W-box binding site in CME

Chen, Z.; Mino, R.; Mettlen, M.; Michaely, P.; Bhave, M.; Reed, D. K.; Schmid, S. L.

10.1101/2020.01.24.919092 — cell biology — Posted on 2020-01-25

969 TNFα/Grnd mediate JNK/MMPs activation during glioma progression and neurodegeneration

Portela, M.; Mitchell, T.; Casas-Tinto, S.

10.1101/2020.01.24.917708 — cancer biology — Posted on 2020-01-25

970 Under-the-radar dengue virus infections in natural populations of Aedes aegypti mosquitoes

Boyles, S. M.; Mavian, C. N.; Finol, E.; Ukhanova, M.; Stephenson, C. J.; Hamerlinck, G.; Kang, S.; Baumgartner, C.; Geesey, M.; Stinton, I.; Williams, K.; Mathias, D. K.; Prosperi, M.; Mai, V.; Salemi, M.; Buckner, E. A.; Lednicky, J. A.; Rivers, A. R.; Dinglasan, R. R.

10.1101/2020.01.24.919282 — ecology — Posted on 2020-01-25

971 Host and infectivity prediction of Wuhan 2019 novel coronavirus using deep learning algorithm

Guo, Q.; Li, M.; Wang, C.; Fang, Z.; Wang, P.; Tan, J.; Wu, S.; Xiao, Y.; Zhu, H.

10.1101/2020.01.21.914044 — systems biology — Posted on 2020-01-25

972 Unconscious perception can be predicted from prestimulus activity

Railo, H.; Piccin, R.; Lukasik, K. M.

10.1101/2020.01.06.896803 — neuroscience — Posted on 2020-01-25

973 A template-matching algorithm for laminar identification of cortical recording sites from evoked response potentials

Matteucci, G.; Riggi, M.; Zoccolan, D.

10.1101/749069 — neuroscience — Posted on 2020-01-25

974 Tree demographic performance of European tree species at their hot and cold edges.

Kunstler, G.; Guyennon, A.; Ratcliffe, S.; Ruger, N.; Ruiz-Benito, P.; Childs, D. Z.; Dahlgren, J.; Lehtonen, A.; Thuiller, W.; Wirth, C.; Zavala, M. A.; Salguero-Gomez, R.

10.1101/801084 — ecology — Posted on 2020-01-25

975 Inertial sensor-based centripetal acceleration as a correlate for lateral margin of stability during walking and turning

Fino, P. C.; Horak, F. B.; Curtze, C.

10.1101/768192 — bioengineering — Posted on 2020-01-25

Baden, A. L.; Webster, T. H.; Bradley, B. J.

10.1101/799825 — animal behavior and cognition — Posted on 2020-01-25

977 METTL4 catalyzes m6Am methylation in U2 snRNA to regulate pre-mRNA splicing

Goh, Y. T.; Koh, C. W. Q.; Sim, D. Y.; Roca, X.; Goh, W. S. S.

10.1101/2020.01.24.917575 — molecular biology — Posted on 2020-01-25

978 Transcriptional analysis supports the expression of human snRNA variants and reveals U2 snRNA homeostasis by an abundant U2 variant

Kosmyna, B.; Gupta, V.; Query, C. C.

10.1101/2020.01.24.917260 — molecular biology — Posted on 2020-01-25

979 Definition of the fibroblast adhesome using multiplexed proximity biotinylation

Chastney, M. R.; Lawless, C.; Humphries, J. D.; Warwood, S.; Jones, M. C.; Knight, D.; Jorgensen, C.; Humphries, M. J.

10.1101/2020.01.24.918458 — cell biology — Posted on 2020-01-25

980 Local stabilization of subunit-subunit contacts causes global destabilization of Hepatitis B virus capsids

Schlicksup, C.; Laughlin, P.; Dunkelbarger, S.; Wang, J. C.-Y.; Zlotnick, A.

10.1101/2020.01.24.918904 — biochemistry — Posted on 2020-01-25

981 Linking endoplasmic reticulum stress to polyploidy in ovarian cancer cells

Yart, L.; Bastida-Ruiz, D.; wuillemin, c.; ribaux, p.; allard, m.; dietrich, p.-y.; petignat, p.; cohen, m.

10.1101/2020.01.24.918029 — cell biology — Posted on 2020-01-24

982 The allosteric control mechanism of bacterial glycogen biosynthesis disclosed by cryoEM

Cifuente, J. O.; Comino, N.; D'Angelo, C.; Marina, A.; Gil-Carton, D.; Albesa-Jove, D.; Guerin, M. E.

10.1101/2020.01.24.916759 — biochemistry — Posted on 2020-01-24

983 Crystal Structure of the Tof1-Csm3 (Timeless-Tipin) Fork Protection Complex

Grabarczyk, D. B.

10.1101/2020.01.24.918474 — biochemistry — Posted on 2020-01-24

984 A Fob1 independent role for the Smc5/6 complex in the rDNA that modulates lifespan.

Moradi Fard, S.; Mojumdar, A.; Chan, M.; Harkness, T. A. A.; Cobb, J. A.

10.1101/2020.01.24.917203 — molecular biology — Posted on 2020-01-24

985 Msps Governs Acentrosomal Microtubule Assembly and Reactivation of Quiescent Neural Stem Cells

Wang, H.; Deng, Q.; Tan, Y. S.; Chew, L. Y.

10.1101/2020.01.24.918227 — developmental biology — Posted on 2020-01-24

986 PAT2 regulates autophagy through vATPase assembly and lysosomal acidification in brown adipocytes

Wang, J.; Krueger, M.; Hauck, S. M.; Ussar, S.

10.1101/2020.01.24.918078 — cell biology — Posted on 2020-01-24

987 Tandem tension sensor reveals substrate rigidity-dependence of integrin molecular tensions in live cells

Sarkar, A.; LeVine, D.; Zhao, Y.; Mollaeian, K.; Ren, J.; Wang, X.

10.1101/2020.01.24.918946 — biophysics — Posted on 2020-01-24

988 Structural and Functional NIR-II Fluorescence Bioimaging in Urinary System via Clinically Approved Dye Methylene Blue

Xue, D.; Wu, D.; Lu, Z.; Zebibula, A.; Feng, Z.; Qian, J.; Li, G.

10.1101/2020.01.24.917955 — bioengineering — Posted on 2020-01-24

989 Single molecule imaging reveals cFos is capable of binding to and diffusing on DNA tightropes independently of cJun

Leech, J. T.; Don, N. A.; Mason, J. M.; Kad, N. M.

10.1101/2020.01.24.918300 — biochemistry — Posted on 2020-01-24

990 Host-derived Circular RNAs Display Proviral Activities in Hepatitis C Virus - Infected Cells

Chen, T.-C.; Tallo-Parra, M.; Kadener, S.; Böttcher, R.; Perez-Vilaro, G.; Boonchuen, P.; Somboonwiwat, K.; Diez, J.; Sarnow, P.

10.1101/2020.01.24.917971 — microbiology — Posted on 2020-01-24

991 Can Intestinal Absorption of Dietary Protein Be Improved Through Early Exposure to Plant-Based Diet?

Molinari, G. S.; McCracken, V. J.; Wojno, M.; Rimoldi, S.; Terova, G.; Kwasek, K.

10.1101/2020.01.24.917856 — zoology — Posted on 2020-01-24

992 A systematic review of scientific research focused on farmers in agricultural adaptation to climate change (2008-2017)

Yang, Y.; Seyler, B. C.; Feng, M.; Tang, Y.

10.1101/2020.01.24.917864 — scientific communication and education — Posted on 2020-01-24

993 Ameliorative effect of a quinazoline-based bromodomain inhibitor, CN210, on experimentally-induced Crohn's disease-like murine ileitis via inhibition of inflammatory cytokine expression

Noguchi, T.; Hidaka, K.; Kobayashi, S.; Matsumoto, K.; Yoshioka, M.; Yang, S.-M.; Maloney, D. J.; Kato, S.

10.1101/2020.01.24.917948 — pharmacology and toxicology — Posted on 2020-01-24

994 Differential effects of aquaporin-4 channel inhibition on BOLD fMRI and Diffusion fMRI responses in rat visual cortex

Komaki, Y.; Debacker, C.; Djemai, B.; Ciobanu, L.; Tsurugizawa, T.; Le Bihan, D.

10.1101/2020.01.24.917849 — neuroscience — Posted on 2020-01-24

995 Isolation and characterization of bovine herpes virus 5 (BHV5) from cattle in India

Kumar, N.; Chander, Y.; Riyesh, T.; Khandelwal, N.; Kumar, R.; Kumar, H.; Tripathi, B. N.; Barua, S.

10.1101/2020.01.24.917880 — microbiology — Posted on 2020-01-24

996 Comparing DNA replication programs reveals large timing shifts at centromeres of endocycling cells in maize roots

Wear, E. E.; Song, J.; Zynda, G. J.; Mickelson-Young, L.; LeBlanc, C.; Lee, T.-J.; Deppong, D. O.; Allen, G. C.; Martienssen, R. A.; Vaughn, M. W.; Hanley-Bowdoin, L.; Thompson, W. F.

10.1101/2020.01.24.917914 — genomics — Posted on 2020-01-24

997 Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina

Luisi, P.; Garcia, A.; Berros, J. M.; Motti, J.; Demarchi, D.; Alfaro, E.; Aquilano, E.; Argüelles, C.; Avena, S.; Bailliet, G.; Beltramo, J.; Bravi, C.; Cuello, M.; Dejean, C.; Dipierri, J. E.; Jurado Medina, L.; Lanata, J. L.; Muzzio, M.; Parolin, M. L.; Pauro, M.; Paz Sepulveda, P. B.; Rodriguez Golpe, D.; Santos, M. R.; Schwab, M.; Silverio, N.; Zubrzycki, J.; Ramallo, V.; Dopazo, H.

10.1101/2020.01.24.917898 — genetics — Posted on 2020-01-24

998 Pesticides and transgenerational inheritance of pathologies: Designing, analysing and reporting rodent studies.

Plewis, I.

10.1101/2020.01.24.917930 — genetics — Posted on 2020-01-24

999 Identification of microRNAs involved in NOD-dependent induction of pro-inflammatory genes in pulmonary endothelial cells

Vlacil, A.-K.; Vollmeister, E.; Bertrams, W.; Schoesser, F.; Oberoi, R.; Schuett, J.; Schuett, H.; Huehn, S.; Bedenbender, K.; Schmeck, B. T.; Schieffer, B.; Grote, K.

10.1101/2020.01.24.917963 — cell biology — Posted on 2020-01-24

1000 SMART-Q: An Integrative Pipeline Quantifying Cell Type-Specific RNA Transcription

Shen, Y.; Bergenholtz, S.; Yang, X.; Li, Y.

10.1101/2020.01.24.917872 — cell biology — Posted on 2020-01-24

1001 Comparison of Anorectal Function Measured using Wearable Digital Manometry and a High Resolution Manometry System.

Attari, A.; Chey, W. D.; Baker, J. R.; Ashton-Miller, J. A.

10.1101/2020.01.24.917922 — bioengineering — Posted on 2020-01-24

1002 Regulation of olfactory-based sex behaviors in the silkworm by genes in the sex-determination cascade

Xu, J.; Liu, W.; Yang, D.; Chen, S.; Chen, K.; Liu, Z.; Yang, X.; Meng, J.; Zhu, G.; Dong, S.; Zhang, Y.; Zhan, S.; Wang, G.; Huang, Y.

10.1101/2020.01.24.917906 — genetics — Posted on 2020-01-24

1003 The dendritic spatial code: branch-specific place tuning and its experience-dependent decoupling

Rashid, S. K.; Pedrosa, V.; Dufour, M. A.; Moore, J. J.; Chavlis, S.; Delatorre, R. G.; Poirazi, P.; Clopath, C.; Basu, J.

10.1101/2020.01.24.916643 — neuroscience — Posted on 2020-01-24

1004 Spatial-temporal dynamics of a microbial cooperative behavior robust to cheating

Monaco, H.; Sereno, T.; Liu, K.; Reagor, C.; Deforet, M.; Xavier, J.

10.1101/2020.01.23.914481 — systems biology — Posted on 2020-01-24

1005 A metabolomics study of ascorbic acid-induced in situ freezing tolerance in spinach (Spinacia oleracea L.)

Arora, R.; Min, K.; Chen, K.

10.1101/2020.01.23.916973 — plant biology — Posted on 2020-01-24

1006 Dose-dependent effects of netarsudil, a Rho-kinase inhibitor, on the distal outflow tract

Chen, S.; Waxman, S.; Wang, C.; Atta, S.; Loewen, R.; Loewen, N. A.

10.1101/2020.01.17.909101 — physiology — Posted on 2020-01-24

1007 Assessing Goodness-of-Fit in Marked-Point Process Models of Neural Population Coding via Time and Rate Rescaling

Amidi, Y.; Yousefi, A.; Nazari, B.; Eden, U.

10.1101/2020.01.24.919050 — neuroscience — Posted on 2020-01-24

1008 Cities have a negative impact on navigation ability: evidence from 38 countries

Coutrot, A.; Manley, E.; Yesiltepe, D.; Dalton, R. C.; Wiener, J. M.; Holscher, C.; Hornberger, M.; Spiers, H. J.

10.1101/2020.01.23.917211 — neuroscience — Posted on 2020-01-24

1009 Connectome-wide search for functional connectivity locus associated with pathological rumination as a target for real-time fMRI neurofeedback intervention

Misaki, M.; Tsuchiyagaito, A.; Al Zoubi, O.; Paulus, M.; Bodurka, J.; Tulsa 1000 Investigators,

10.1101/2020.01.24.910430 — neuroscience — Posted on 2020-01-24

1010 Macrophages Promote Aortic Valve Cell Calcification Through STAT3 Splicing

Raddatz, M.; Huffstater, T.; Bersi, M. R.; Reinfeld, B.; Madden, M.; Booton, S.; Rathmell, K.; Rathmell, J. C.; Lindman, B.; Madhur, M.; Merryman, W. D.

10.1101/2020.01.24.919001 — molecular biology — Posted on 2020-01-24

1011 Plasmid diversity among genetically related Klebsiella pneumoniae blaKPC-2 and blaKPC-3 isolates collected in the Dutch national surveillance

Hendrickx, A. P. A.; Landman, F.; de Haan, A.; Borst, D.; Witteveen, S.; van Santen-Verheuvel, M. G.; van der Heide, H. G.; Schouls, L. M.

10.1101/2020.01.23.917781 — microbiology — Posted on 2020-01-24

1012 Estimation of Full-Length TprK Diversity in Treponema pallidum subspecies pallidum

Addetia, A.; Lin, M. J.; Phung, Q.; Xie, H.; Huang, M.; Ciccarese, G.; Dal Conte, I.; Cusini, M.; Drago, F.; Giacani, L.; Greninger, A. L.

10.1101/2020.01.23.917484 — microbiology — Posted on 2020-01-24

1013 Virion-associated spermidine transmits with Rift Valley fever virus particles to maintain infectivity

Mastrodomenico, V.; Esin, J. J.; Qazi, S.; Omoba, O. S.; Fung, B. L.; Khomutov, M. A.; Ivanov, A. V.; Mukhopadhyay, S.; Mounce, B. C.

10.1101/2020.01.23.915900 — microbiology — Posted on 2020-01-24

1014 Comprehensive bioinformatic analysis of newly sequenced Turdoides affinis mitogenome reveals the persistence of translational efficiency and dominance of NADH dehydrogenase complex-I in electron transport system over Leiothrichidae family

Sarkar, I.; Dey, P.; Sharma, S. K.; Ray, S. D.; Singh, R. P.

10.1101/2020.01.23.917716 — genomics — Posted on 2020-01-24

1015 Rapid and scalable profiling of nascent RNA with fastGRO

Barbieri, E.; Hill, C.; Quesnel-Vallieres, M.; Barash, Y.; Gardini, A.

10.1101/2020.01.24.916015 — genomics — Posted on 2020-01-24

1016 USP15 deubiquitinase safeguards hematopoiesis and genome integrity in hematopoietic stem cells and leukemia cells

van den Berk, P.; Lancini, C.; Company, C.; Serresi, M.; Hulsman, D.; Pritchard, C.; Song, J.-Y.; Schmitt, M. J.; Tanger, E.; Huijbers, I. J.; Jacobs, H.; van Lohuizen, M.; Gargiulo, G.; Citterio, E.

10.1101/2020.01.23.916627 — genetics — Posted on 2020-01-24

1017 Molecular evolution of luciferase diversified bioluminescent signals in sea fireflies (Crustacea:Ostracoda:Cypridinidae)

Hensley, N. M.; Ellis, E. A.; Leung, N. Y.; Coupart, J.; Mikhailovsky, A.; Taketa, D. A.; Tessler, M.; Gruber, D. F.; De Tomaso, A. W.; Rivers, T. J.; Gerrish, G. A.; Torres, E.; Oakley, T. H.

10.1101/2020.01.23.917187 — evolutionary biology — Posted on 2020-01-24

1018 Enhancing CO2-valorization using Clostridium autoethanogenum for sustainable fuel and chemicals production

Heffernan, J. K.; Valgepea, K.; Lemgruber, R. d. S. P.; Casini, I.; Plan, M.; Tappel, R.; Simpson, S. D.; Koepke, M.; Nielsen, L. K.; Marcellin, E.

10.1101/2020.01.23.917666 — bioengineering — Posted on 2020-01-24

1019 Disruption of cross-feeding interactions by invading taxa can cause invasional meltdown in microbial communities

Herren, C. M.

10.1101/2020.01.23.917013 — ecology — Posted on 2020-01-24

1020 Designing Effective small interfering RNA for Post-Transcriptional Silencing of Human GREM1: A Comprehensive Bioinformatics Approach

ASIEDU, E.

10.1101/2020.01.23.917559 — bioinformatics — Posted on 2020-01-24

1021 VINYL: Variant prIoritizatioN bY survivaL analysis

Chiara, M.; Mandreoli, P.; Tangaro, M. A.; D'Erchia, A. M.; Sorrentino, S.; Forleo, C.; Horner, D. S.; Zambelli, F.; Pesole, G.

10.1101/2020.01.23.917229 — bioinformatics — Posted on 2020-01-24

1022 A real-time search strategy for finding urban disease vector infestations

Billig Rose, E.; Roy, J. A.; Castillo-Neyra, R.; Ross, M. E.; Condori-Pino, C.; Peterson, J. K.; Naquira-Velarde, C.; Levy, M. Z.

10.1101/2020.01.20.911974 — bioinformatics — Posted on 2020-01-24

1023 Diversity and Structural Variability of Bacterial Microbial Communities in Rhizocompartments of Desert Leguminous Plants

Zhou, Z.; Ding, G.; Yu, M.; Gao, G.; Wang, G.

10.1101/2020.01.23.917765 — ecology — Posted on 2020-01-24

1024 Mineralized collagen scaffolds fabricated with amniotic membrane matrix increase osteogenesis under inflammatory conditions

Dewey, M.; Johnson, E.; Slater, S.; Milner, D.; Wheeler, M.; Harley, B.

10.1101/2020.01.23.917443 — bioengineering — Posted on 2020-01-24

1025 When enemies do not become friends: Experimental evolution of heat-stress adaptation in a vertically transmitted parasite

Dusi, E.; Krenek, S.; Petzoldt, T.; Kaltz, O.; Berendonk, T.

10.1101/2020.01.23.917773 — evolutionary biology — Posted on 2020-01-24

1026 Finer Metagenomic Reconstruction via Biodiversity Optimization

Foucart, S.; Koslicki, D.

10.1101/2020.01.23.916924 — bioinformatics — Posted on 2020-01-24

1027 An information-theoretic approach for measuring the distance of organ tissue samples using their transcriptomic signatures

Manatakis, D. V.; VanDevender, A.; Manolakos, E. S.

10.1101/2020.01.23.917245 — bioinformatics — Posted on 2020-01-24

1028 A Spiking Neural Network Model for Category Learning

Iyer, L. R.; Basu, A.

10.1101/2020.01.23.916593 — bioengineering — Posted on 2020-01-24

1029 Dugesia japonica is the best suited of three planarian species for high-throughput toxicology screening

Ireland, D.; Bochenek, V.; Chaiken, D.; Rabeler, C.; Onoe, S.; Soni, A.; Collins, E.-M. S.

10.1101/2020.01.23.917047 — pharmacology and toxicology — Posted on 2020-01-24

1030 Divided Attention in Perception:A Unified Analysis of Dual-Task Deficits and Congruency Effects

Palmer, J.; White, A. L.; Moore, C. M.; Boynton, G. M.

10.1101/2020.01.23.917492 — neuroscience — Posted on 2020-01-24

1031 Analysis of cell-associated DENV RNA by oligo(dT) primed 5' capture scRNAseq

Sanborn, M. A.; Li, T.; Victor, K.; Siegfried, H.; Fung, C.; Rothman, A. L.; Srikiatkhachorn, A.; Fernandez, S.; Ellison, D. W.; Jarman, R.; Friberg, H.; Maljkovic Berry, I.; Currier, J. R.; Waickman, A.

10.1101/2020.01.23.917757 — microbiology — Posted on 2020-01-24

1032 Analysis of KSHV B lymphocyte lineage tropism in human tonsil reveals efficient infection of CD138+ plasma cells

Aalam, F.; Nabiee, R.; Castano, J. R.; Totonchy, J.

10.1101/2020.01.17.910612 — immunology — Posted on 2020-01-24

1033 Genome Sequences of Burkholderia thailandensis strains E421, E426, and DW503

Mageeney, C. M.; Sinha, A.; Williams, K. P.; Branda, S. S.

10.1101/2020.01.24.915645 — genomics — Posted on 2020-01-24

1034 Natural selection maintains species despite widespread hybridization in the desert shrub Encelia

DiVittorio, C. D.; Singhal, S.; Roddy, A.; Zapata, F.; Ackerly, D. D.; Baldwin, B. G.; Brodersen, C. R.; Burquez, A.; Fine, P. V.; Padilla Flores, M.; Solis, E.; Morales-Villavicencio, J.; Morales-Arce, D.; Kyhos, D. W.

10.1101/2020.01.23.917021 — evolutionary biology — Posted on 2020-01-24

1035 An atlas of cell types in the mammalian epididymis and vas deferens

Rinaldi, V.; Donnard, E.; Gellatly, K.; Rasmussen, M.; Kucukural, A.; Yukselen, O.; Garber, M.; Sharma, U.; Rando, O.

10.1101/2020.01.24.918979 — developmental biology — Posted on 2020-01-24

1036 LRRK2 mediates tubulation and vesicle sorting from membrane damaged lysosomes

Bonet-Ponce, L.; Beilina, A.; Williamson, C.; Lindberg, E.; Kluss, J. H.; Saez-Atienzar, S.; Landeck, N.; Kumaran, R.; Mamais, A.; Bleck, C. K. E.; Li, Y.; Cookson, M. R.

10.1101/2020.01.23.917252 — cell biology — Posted on 2020-01-24

1037 Identification of a blood test-based biomarker of aging through deep learning of aging trajectories in large phenotypic datasets of mice

Avchaciov, K.; Antoch, M. P.; Andrianova, E. L.; Tarkhov, A. E.; Menshikov, L. I.; Gudkov, A. V.; Fedichev, P. O.

10.1101/2020.01.23.917286 — bioinformatics — Posted on 2020-01-24

1038 Functional heterogeneity in the fermentation capabilities of the healthy human gut microbiota

Gurry, T.; Nguyen, L. T. T.; Yu, X.; Alm, E. J.

10.1101/2020.01.17.910638 — systems biology — Posted on 2020-01-24

1039 Host and infectivity prediction of Wuhan 2019 novel coronavirus using deep learning algorithm

Zhu, H.; Guo, Q.; Li, M.; Wang, C.; Fang, Z.; Wang, P.; Tan, J.; Wu, S.; Xiao, Y.

10.1101/2020.01.21.914044 — systems biology — Posted on 2020-01-24

1040 3D-Reconstruction of the Human Conventional Outflow System by Ribbon Scanning Confocal Microscopy

Loewen, R.; Waxman, S.; Wang, C.; Atta, S.; Chen, S.; Watkins, S. C.; Watson, A. M.; Loewen, N. A.

10.1101/2020.01.17.910257 — physiology — Posted on 2020-01-24

1041 Cardiomyocyte-specific ACSL1 Deficiency Prevents Cardiac Lipotoxicity and Alleviates Heart Dysfunction in the ob/ob Model of Obesity

Pascual, F.; Grevengoed, T. J.; Zhao, L.; Willis, M. S.; Coleman, R. A.

10.1101/2020.01.24.918961 — physiology — Posted on 2020-01-24

1042 Maternal Anxious Attachment Style is Associated with Reduced Mother-Child Brain-to-Brain Synchrony

Azhari, A.; Gabrieli, G.; Bizzego, A.; Bornstein, M. H.; Esposito, G.

10.1101/2020.01.23.917641 — neuroscience — Posted on 2020-01-24

1043 Interleukin-35 pretreatment attenuates lipopolysaccharide-induced heart injury by inhibition of inflammation, apoptosis and fibrosis

Fu, Y.; Hu, H.; Li, M.; Xia, H.; Liu, Y.; Sun, X.; Hu, Y.; Song, F.; Cheng, X.; Li, P.; Wu, Y.

10.1101/2020.01.23.916890 — molecular biology — Posted on 2020-01-24

1044 Vast diversity of anti-CRISPR proteins predicted with a machine-learning approach

Gussow, A.; Shmakov, S. A.; Makarova, K. S.; Wolf, Y. I.; Bondy-Denomy, J.; Koonin, E. V.

10.1101/2020.01.23.916767 — microbiology — Posted on 2020-01-24

1045 Pattern of early human-to-human transmission of Wuhan 2019-nCoV

Riou, J.; Althaus, C. L.

10.1101/2020.01.23.917351 — microbiology — Posted on 2020-01-24

1046 High-quality human preimplantation embryos stimulate endometrial stromal cell migration via secretion of microRNA hsa-miR-320a

Berkhout, R. P.; Keijser, R.; Repping, S.; Lambalk, C. B.; Afink, G. B.; Mastenbroek, S.; Hamer, G.

10.1101/2020.01.21.913632 — developmental biology — Posted on 2020-01-24

1047 Heparan sulfate structure is influenced by the ER-Golgi dynamics of its modifying enzymes

Meneghetti, M.; Deboni, P.; Palomino, C.; Braga, L.; Cavalheiro, R.; Viana, G.; Yates, E.; Nader, H.; Lima, M.

10.1101/2020.01.23.916940 — cell biology — Posted on 2020-01-24

1048 Genetics survey reveals colonization and philopatry of the loggerhead sea turtles across geographic scales

Baltazar-Soares, M.; Klein, J. L.; Correia, S. M.; Reischig, T.; Taxonera, A. A.; Monteiro, S. R.; Dos Passos, L.; Melo, T.; Lomba, J. P.; Diniz, H.; Stiebens, V. A.; Eizaguirre, C.

10.1101/2020.01.23.916866 — evolutionary biology — Posted on 2020-01-24

1049 Bacterial FtsZ induces mitochondrial fission in human cells

Spier, A.; Sachse, M.; Tham, N. T.; Matondo, M.; Cossart, P.; Stavru, F.

10.1101/2020.01.24.917146 — cell biology — Posted on 2020-01-24

1050 fMRI signatures of motor sequence learning: A critical re-evaluation

Berlot, E.; Popp, N. J.; Diedrichsen, J.

10.1101/2020.01.08.899229 — neuroscience — Posted on 2020-01-24

1051 A high-density narrow-field inhibitory retinal interneuron with direct coupling to Müller glia

Grimes, W. N.; Aytürk, D. G.; Hoon, M.; Yoshimatsu, T.; Gamlin, C.; Carrera, D.; Ahlquist, R. M.; Sabnis, A.; Diamond, J. S.; Wong, R. O.; Cepko, C.; Rieke, F.

10.1101/2020.01.23.917096 — neuroscience — Posted on 2020-01-24

1052 Microbial DNA on the move: sequencing based detection and analysis of transduced DNA in pure cultures and microbial communities

Kleiner, M.; Bushnell, B.; Sanderson, K. E.; Hooper, L. V.; Duerkop, B. A.

10.1101/2020.01.15.908442 — microbiology — Posted on 2020-01-24

1053 Activation of cryptic splicing in bovine WDR19 is associated with reduced semen quality and male fertility

Hiltpold, M.; Niu, G.; Kadri, N. K.; Crysnanto, D.; Fang, Z.-H.; Spengeler, M.; Schmitz-Hsu, F.; Fuerst, C.; Schwarzenbacher, H.; Seefried, F. R.; Seehusen, F.; Witschi, U.; Schnieke, A.; Fries, R.; Bollwein, H.; Flisikowski, K.; Pausch, H.

10.1101/2020.01.16.907865 — genomics — Posted on 2020-01-24

1054 Food for the Empire: dietary pattern of Imperial Rome inhabitants.

De Angelis, F.; Varano, S.; Battistini, A.; Di Giannantonio, S.; Ricci, P.; Lubritto, C.; Facchin, G.; Brancazi, L.; Santangeli Valenzani, R.; Catalano, P.; Gazzaniga, V.; Rickards, O.; Martinez-Labarga, C.

10.1101/2020.01.23.911370 — evolutionary biology — Posted on 2020-01-24

1055 Cancer PRSweb - an Online Repository with Polygenic Risk Scores (PRS) for Major Cancer Traits and Their Phenome-wide Exploration in Two Independent Biobanks

Fritsche, L. G.; Patil, S.; Beesley, L. J.; VandeHaar, P.; Salvatore, M.; Peng, R. B.; Taliun, D.; Zhou, X.; Mukherjee, B.

10.1101/2020.01.22.915751 — genetics — Posted on 2020-01-24

1056 Calcium induced calcium release in proximity to hair cell BK channels revealed by PKA activation

Bai, J.; Xue, N.; Lawal, O.; Nyati, A.; Santos-Sacchi, J.; Navaratnam, D. S.

10.1101/2019.12.30.890558 — physiology — Posted on 2020-01-24

1057 A unique predator in a unique ecosystem: modelling the apex predator from the Late Cretaceous crocodyliform-dominated fauna in Brazil.

Montefeltro, F. C.; Lautenschlager, S.; Godoy, P. L.; Ferreira, G. S.; Butler, R. J.

10.1101/843334 — paleontology — Posted on 2020-01-24

1058 Distinct neural variables underlie subjective reports of attention

Whitmarsh, S.; Gitton, C.; Sackur, J.; Tallon-Baudry, C.

10.1101/2020.01.23.916841 — neuroscience — Posted on 2020-01-24

1059 When honest people cheat, and cheaters are honest: Cognitive control processes override our moral default

Speer, S. P. H.; Smidts, A.; Boksem, M. A. S.

10.1101/2020.01.23.907634 — neuroscience — Posted on 2020-01-24

1060 The effects of cannabidiol on cue- and stress-induced reinstatement of cocaine seeking behavior in mice are reverted by the CB1 receptor antagonist AM4113.

Lujan, M. A.; Alegre-Zurano, L.; Martin-Sanchez, A.; Valverde, O.

10.1101/2020.01.23.916601 — neuroscience — Posted on 2020-01-24

1061 End-to-end multitask learning, from protein language to protein features without alignments

Elnaggar, A.; Heinzinger, M.; Dallago, C.; Rost, B.

10.1101/864405 — bioinformatics — Posted on 2020-01-24

1062 Spectral Graph Theory of Brain Oscillations

Raj, A.; Cai, C.; Xie, X.; Palacios, E.; Owen, J.; Mukherjee, P.; Nagarajan, S.

10.1101/589176 — neuroscience — Posted on 2020-01-24

1063 Calcium-permeable AMPA receptors mediate timing-dependent LTP elicited by six coincident action potentials at Schaffer collateral-CA1 synapses

Cepeda-Prado, E. A.; Khodaie, B.; Quiceno, G. D.; Beythien, S.; Lessmann, V.; Edelmann, E.

10.1101/719633 — neuroscience — Posted on 2020-01-24

1064 New insights on the ventral attention network: Active suppression and involuntary recruitment during a bimodal task

Solis-Vivanco, R.; Jensen, O.; Bonnefond, M.

10.1101/782649 — neuroscience — Posted on 2020-01-24

1065 Remembrance of things practiced: Fast and slow learning in cortical and subcortical pathways

Murray, J. M.; Escola, S.

10.1101/797548 — neuroscience — Posted on 2020-01-24

1066 Genome-wide dysregulation of histone acetylation in the Parkinsons disease brain

Toker, L.; Tran, G. T.; Sundaresan, J.; Tysnes, O.-B.; Alves, G.; Haugarvoll, K.; Nido, G. S.; Dolle, C.; Tzoulis, C.

10.1101/785550 — genomics — Posted on 2020-01-24

1067 Chromatin accessibility and histone acetylation in the regulation of competence in early development

Esmaeili, M.; Blythe, S. A.; Tobias, J. W.; Zhang, K.; Yang, J.; Klein, P. S.

10.1101/797183 — developmental biology — Posted on 2020-01-24

1068 Predicting the global mammalian viral sharing network using phylogeography

Albery, G. F.; Eskew, E. A.; Ross, N.; Olival, K. J.

10.1101/732255 — ecology — Posted on 2020-01-24

1069 Extracellular caspase-1 regulates hair follicle stem cell migration during wound-healing

Ghosh, S.; Ananthan, A. S.; Kataria, S.; Pincha, N.; Dutta, A.; Athreya, S.; Bhosale, A.; Dey, R.; Jamora, C.

10.1101/548529 — cell biology — Posted on 2020-01-24

1070 Cooperation and Stability for Complex Systems in Resource-Limited Environments

Butler, S.; O'Dwyer, J. P.

10.1101/514018 — ecology — Posted on 2020-01-24

1071 Low-N protein engineering with data-efficient deep learning

Biswas, S.; Khimulya, G.; Alley, E. C.; Esvelt, K. M.; Church, G. M.

10.1101/2020.01.23.917682 — synthetic biology — Posted on 2020-01-24

1072 Variation in maize chlorophyll biosynthesis alters plant architecture

Khangura, R.; Johal, G.; Dilkes, B.

10.1101/2020.01.24.917732 — plant biology — Posted on 2020-01-24

1073 Transient amplitude modulation of alpha-band oscillations by short-time intermittent closed-loop tACS

Zarubin, G.; Gundlach, C.; Nikulin, V.; Villringer, A.; Bogdan, M.

10.1101/2020.01.23.916676 — neuroscience — Posted on 2020-01-24

1074 Hmx3a does not require its homeodomain for its essential functions in spinal cord, ear and lateral line development.

England, S. J.; Cerda, G. A.; Kowalchuk, A. M.; Sorice, T.; Grieb, G. M.; Lewis, K. E.

10.1101/2020.01.23.917468 — genetics — Posted on 2020-01-24

1075 Consumption rate and dietary choice of cattle in species-rich mesic grasslands

Balogh, N.; Tothmeresz, B.; Valko, O.; Deak, B.; Toth, K.; Molnar, Z.; Vadasz, C.; Toth, E.; Kiss, R.; Sonkoly, J.; Török, P.; Karoly, A.; Tüdösne Budai, J.; Miglecz, T.; Kelemen, A.

10.1101/2020.01.23.916635 — ecology — Posted on 2020-01-24

1076 Genomic alterations and abnormal expression of APE2 in multiple cancers

Jensen, K. A.; Shi, X.; Yan, S.

10.1101/2020.01.17.910646 — bioinformatics — Posted on 2020-01-24

1077 Glial insulin regulates cooperative or antagonistic Golden goal/Flamingo interactions during photoreceptor axon navigation

Takechi, H.; Hakeda-Suzuki, S.; Nitta, Y.; Ishiwata, Y.; Sato, M.; Sugie, A.; Suzuki, T.

10.1101/2020.01.23.916403 — neuroscience — Posted on 2020-01-24

1078 DPSN: standardizing the short names of amplicon-sequencing primers to avoid ambiguity

Tan, Y.; Tian, Y.; Chen, J.; Yin, Z.; Yang, H.

10.1101/2020.01.23.916429 — microbiology — Posted on 2020-01-24

1079 Oncogenic memory underlying minimal residual disease in breast cancer

Shechter, K. R.; Kafkia, E.; Zirngibl, K.; Gawrzak, S.; Alladin, A.; Machado, D.; Luechtenborg, C.; Sevin, D. C.; Bruegger, B.; Patil, K. R.; Jechlinger, M.

10.1101/2020.01.23.916510 — cancer biology — Posted on 2020-01-24

1080 Pioneer transcription factors in chromatin remodeling: the kinetic proofreading view

Schiessel, H.; Blossey, R.

10.1101/2020.01.24.916908 — biophysics — Posted on 2020-01-24

1081 O-GlcNAc Transferase Activity is Essential for RNA Pol II Pausing in a Human Cell-Free Transcription System

Lewis, B. A.; Levens, D.

10.1101/2020.01.23.917237 — biochemistry — Posted on 2020-01-24

1082 Regulation of human development by ubiquitin chain editing of chromatin remodelers

Beck, D.; Basar, M. A.; Asmar, A. J.; Thompson, J.; Oda, H.; Uehara, D. T.; Saida, K.; Bodurtha, J.; d Souza, P.; Mu, W.; Baranano, K. W.; Miyake, N.; Wang, R.; Kempers, M.; Nishimura, Y.; Okada, S.; Kosho, T.; Dale, R.; Mitra, A.; Macnamara, E.; Undiagnosed Diseases Network, ; Matsumoto, N.; Inazawa, J.; Walkiewicz, M.; Tifft, C. J.; Aksentijevich, I.; Kastner, D. L.; Rocha, P. P.; Werner, A.

10.1101/2020.01.23.917450 — genetics — Posted on 2020-01-24

1083 MK2-deficient mice are bradycardic and display delayed hypertrophic remodelling in response to a chronic increase in afterload

Ruiz, M.; Khairallah, M.; Dingar, D.; Vaniotis, G.; Khairallah, R. J.; Lauzier, B.; Thibault, S.; Trepanier, J.; Shi, Y.; Douillette, A.; Hussein, B.; Nawaito, S. A.; Sahadevan, P.; Nguyen, A.; Gillis, M.-A.; Sirois, M. G.; Gaestel, M.; Stanley, W. C.; Fiset, C.; Tardif, J.-C.; Allen, B. G.

10.1101/2020.01.23.916049 — physiology — Posted on 2020-01-24

1084 Independent representations of reward-predicting cues and reward history in frontal cortical neurons

Kondo, M.; Matsuzaki, M.

10.1101/2020.01.23.916460 — neuroscience — Posted on 2020-01-24

1085 Vast differences in strain-level diversity in the gut microbiota of two closely related honey bee species

Ellegaard, K. M.; Suenami, S.; Miyazaki, R.; Engel, P.

10.1101/2020.01.23.916296 — microbiology — Posted on 2020-01-24

1086 Establishment gaps in species-poor grasslands: artificial biodiversity hotspots to support the colonization of target species

Kiss, R.; Deak, B.; Tothmeresz, B.; Miglecz, T.; Toth, K.; Torok, P.; Lukacs, K.; Godo, L.; Kormoczi, Z.; Radocz, S.; Kelemen, A.; Sonkoly, J.; Kirmer, A.; Tischew, S.; Svamberkova, E.; Valko, O.

10.1101/2020.01.23.916155 — ecology — Posted on 2020-01-24

1087 Signals of recent tropical radiations in Cunoniaceae, an iconic family for understanding Southern Hemisphere biogeography

Segovia, R. A.; Griffiths, A. R.; Arenas, D.; Dias, P.; Dexter, K. G.

10.1101/2020.01.23.916817 — ecology — Posted on 2020-01-24

1088 A chemical tool for improved culture of human pluripotent stem cells

Silpa, L.; Schuessler, M.; Liu, G.; Olivecrona, M.; Groizard-Payeras, L.; Couper, E.; Bataille, C. J. R.; Stevenson, M.; Seymour, L. W.; Davies, S. G.; James, W. S.; Cowley, S. A.; Russell, A. J.

10.1101/2020.01.24.918268 — cell biology — Posted on 2020-01-24

1089 The Ketosynthase Domain Constrains the Design of Polyketide Synthases

Klaus, M.; Buyachuihan, L.; Grininger, M.

10.1101/2020.01.23.916668 — biochemistry — Posted on 2020-01-24

1090 Proteogenomic single cell analysis of skeletal muscle myocytes

Fomchenko, K. M.; Verma, R. X.; Kannan, S.; Lin, B. L.; Yang, X.; Nieuwenhuis, T. O.; Patil, A. H.; Fox-Talbot, K.; McCall, M. N.; Kwon, C.; Kass, D. A.; Rosenberg, A. Z.; Halushka, M. K.

10.1101/2020.01.23.916791 — genomics — Posted on 2020-01-24

1091 Multiple streams of genetic diversity in Japonica rice

Santos, J. G.; Billot, C.; Chebotarov, D.; Droc, G.; Lorieux, M.; McNally, K.; Glaszmann, J.-C.

10.1101/2020.01.23.915918 — genomics — Posted on 2020-01-24

1092 Improved accuracy and precision of bioprinting through progressive cavity pump-controlled extrusion

Fisch, P.; Holub, M.; Zenobi-Wong, M.

10.1101/2020.01.23.915868 — bioengineering — Posted on 2020-01-24

1093 A new Spirodela polyrhiza genome and proteome reveal a conserved chromosomal structure with high abundances of proteins favoring energy production

Harkess, A. E.; McLoughlin, F.; Bilkey, N.; Elliott, K.; Emenecker, R.; Mattoon, E.; Miller, K.; Czymmek, K.; Vierstra, R.; Meyers, B. C.; Michael, T.

10.1101/2020.01.23.909457 — plant biology — Posted on 2020-01-24

1094 The ubiquitin ligase Ariadne-1 regulates NSF for neurotransmitter release

Ramirez, J.; Morales, M.; Osinalde, N.; Martinez-Padron, I.; MAYOR, U.; Ferrus, A.

10.1101/2020.01.23.916619 — neuroscience — Posted on 2020-01-24

1095 Most small cerebral cortical veins demonstrate significant flow pulsatility: a human phase contrast MRI study at 7T

Driver, I. D.; Traat, M.; Fasano, F.; Wise, R. G.

10.1101/2020.01.24.912329 — neuroscience — Posted on 2020-01-24

1096 A Primary Neural Cell Culture Model for Neuroinflammation

Goshi, N.; Morgan, R. K.; Lein, P. J.; Seker, E.

10.1101/2020.01.23.914226 — neuroscience — Posted on 2020-01-24

1097 The defining genomic and predicted metabolic features of the Acetobacterium genus

Ross, D. E.; Marshall, C. W.; Gulliver, D.; May, H. D.; Norman, R. S.

10.1101/2020.01.23.904417 — genomics — Posted on 2020-01-24

1098 In Silico Modeling of Metabolic State in Single Th17 Cells Reveals Novel Regulators of Inflammation and Autoimmunity

Wagner, A.; Wang, C.; DeTomaso, D.; Avila-Pacheco, J.; Zaghouani, S.; Fessler, J.; Akama-Garren, E.; Pierce, K.; Ron-Harel, N.; Douglas, V. P.; Haigis, M.; Sobel, R. A.; Clish, C.; Regev, A.; Kuchroo, V. K.; Yosef, N.

10.1101/2020.01.23.912717 — genomics — Posted on 2020-01-24

1099 Unidirectional response to bidirectional selection on body size. II Quantitative genetics.

Le Rouzic, A.; Renneville, C.; Millot, A.; Agostini, S.; Carmignac, D.; Edeline, E.

10.1101/2020.01.23.916361 — evolutionary biology — Posted on 2020-01-24

1100 Food for the Empire: dietary pattern of Imperial Rome inhabitants.

de angelis, f.; Varano, S.; Gazzaniga, V.; Santangeli Valenzani, R.; Brancazi, L.; Facchin, G.; Lubritto, C.; Ricci, P.; Martinez-Labarga, C.; Rickards, O.; Catalano, P.; Battistini, A.; Di Giannantonio, S.

10.1101/2020.01.23.911370 — evolutionary biology — Posted on 2020-01-24

1101 Extreme acid resistance of human cheek epithelial cells.

Ahmad, M.; Mateen, I.; Tahir, A.; Anjum, R. S.

10.1101/2020.01.23.903831 — cell biology — Posted on 2020-01-24

1102 Deforestation in Belize- What, Where and Why

Folkard-Tapp, H. R.

10.1101/2020.01.23.915447 — ecology — Posted on 2020-01-24

1103 Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: A data-driven analysis in the early phase of the outbreak

Zhao, S.; Ran, J.; MUSA, S. S.; Yang, G.; Lou, Y.; Gao, D.; Yang, L.; He, D.

10.1101/2020.01.23.916395 — ecology — Posted on 2020-01-24

1104 The 2019-new Coronavirus epidemic: evidence for virus evolution

Benvenuto, D.; Giovanetti, M.; Ciccozzi, A.; Spoto, S.; Angeletti, S.; Ciccozzi, M.

10.1101/2020.01.24.915157 — bioinformatics — Posted on 2020-01-24

1105 Large-scale DNA-based phenotypic recording and deep learning enable highly accurate sequence-function mapping

Hoellerer, S.; Papaxanthos, L.; Gumpinger, A. C.; Fischer, K.; Beisel, C.; Borgwardt, K.; Benenson, Y.; Jeschek, M.

10.1101/2020.01.23.915405 — synthetic biology — Posted on 2020-01-24

1106 A single nucleotide substitution in TaHKT1;5-D controls shoot Na+ accumulation in bread wheat

Borjigin, C.; Schilling, R. K.; Bose, J.; Hrmova, M.; Qiu, J.; Wege, S.; Situmorang, A.; Brien, C.; Berger, B.; Gilliham, M.; Pearson, A. S.; Roy, S. J.

10.1101/2020.01.21.909887 — plant biology — Posted on 2020-01-24

1107 Hox-dependent coordination of cardiac progenitor cell patterning and differentiation

Stefanovic, S.; Laforest, B.; Desvignes, J.-P.; Lescroart, F.; Argiro, L.; Maurel-Zaffran, C.; Salgado, D.; de Bono, C.; Pazur, K.; Theveniau-Ruissy, M.; Beroud, C.; Puceat, M.; Gavalas, A.; Kelly, R. G.; Zaffran, S.

10.1101/2020.01.23.916981 — developmental biology — Posted on 2020-01-24

1108 A bacterial effector protein prevents MAPK-mediated phosphorylation of SGT1 to suppress plant immunity

Yu, G.; Xian, L.; Xue, H.; Yu, W.; Rufian, J.; Sang, Y.; Morcillo, R.; Wang, Y.; Macho, A.

10.1101/641241 — plant biology — Posted on 2020-01-24

1109 Effect of Perfluorooctanesulfonic acid (PFOS) on immune cell development and function in mice

Torres, L.; Redko, A.; Imbiakha, B.; Limper, C.; Chang, S.; August, A.

10.1101/2020.01.20.913293 — pharmacology and toxicology — Posted on 2020-01-24

1110 Lifespan associated changes in global patterns of coherent communication

Sahoo, B.; Pathak, A.; Deco, G.; Banerjee, A.; Roy, D.

10.1101/504589 — neuroscience — Posted on 2020-01-24

1111 A probabilistic functional parcellation of human occipito-temporal cortex

Rosenke, M.; van Hoof, R.; van den Hurk, J.; Goebel, R.

10.1101/2020.01.22.916239 — neuroscience — Posted on 2020-01-24

1112 A glycogenin homolog controls Toxoplasma gondii growth via glycosylation of an E3 ubiquitin ligase

Mandalasi, M.; Kim, H. W.; Thieker, D.; Sheikh, M. O.; Gas-Pascual, E.; Rahman, K.; Zhao, P.; Daniel, N. G.; van der Wel, H.; Ichikawa, T. H.; Glushka, J. N.; Wells, L.; Woods, R. J.; Wood, Z. A.; West, C. M.

10.1101/764241 — microbiology — Posted on 2020-01-24

1113 Spatial variation in introgression along a toad hybrid zone in France

van Riemsdijk, I.; Arntzen, J. W.; Bucciarelli, G.; McCartney-Melstad, E.; Rafajlovic, M.; Scott, P. A.; Toffelmier, E.; H. Shaffer, B.; Wielstra, B.

10.1101/746073 — evolutionary biology — Posted on 2020-01-24

1114 Antagonistic pathogen-mediated selection favours the maintenance of innate immune gene polymorphism in a widespread wild ungulate

Quemere, E.; Hessenauer, P.; Galan, M.; Fernandez, M.; Merlet, J.; Chaval, Y.; Hewison, A. J. M.; Morellet, N.; Verheyden, H.; Gilot Fromont, E.; Charbonnel, N.

10.1101/458216 — evolutionary biology — Posted on 2020-01-24

1115 Molecular and genetic regulation of pig pancreatic islet cell development

Kim, S.; Whitener, R. L.; Peiris, H.; Gu, X.; Chang, C. A.; Lam, J. Y.; Camunas-Soler, J.; Park, I.; Bevacqua, R.; Tellez, K.; Quake, S. R.; Lakey, J. R. T.; Bottino, R.; Ross, P. J.; Kim, S. K.

10.1101/717090 — developmental biology — Posted on 2020-01-24

1116 In vivo characterisation of the toxicological properties of DPhP, one of the main degradation products of aryl phosphate esters.

Ruby, S.; Marin-Saez, J.; Fildier, A.; Bulete, A.; Abdallah, M.; Garcia, J.; Deverchere, J.; Spinner, L.; Giroud, B.; Ibanez, S.; Granjon, T.; Bardel-Danjean, C.; Fervers, B.; Puisieux, A.; Vulliet, E.; Payen-Gay, L.; Vigneron, A. M.

10.1101/2019.12.26.888057 — pharmacology and toxicology — Posted on 2020-01-24

1117 Imaging real-time tactile interaction with two-person dual-coil fMRI

Renvall, V.; Kauramaki, J.; Malinen, S.; Hari, R.; Nummenmaa, L.

10.1101/861252 — neuroscience — Posted on 2020-01-24

1118 Chromatin accessibility and histone acetylation in the regulation of competence in early development

Esmaeili, M.; Blythe, S. A.; Tobias, J. W.; Zhang, K.; Yang, J.; Klein, P. S.

10.1101/797183 — developmental biology — Posted on 2020-01-24

1119 Regulatory Feedbacks on Receptor and Non-receptor Synthesis for Robust Signaling

Lander, A. D.; Nie, Q.; Sanchez-Tapia, C. H.; Simonyan, A.; Wan, F. Y. M.

10.1101/791509 — developmental biology — Posted on 2020-01-24

1120 A minimal model for microbial biodiversity can reproduce experimentally observed ecological patterns

Marsland, R.; Cui, W.; Mehta, P.

10.1101/622829 — microbiology — Posted on 2020-01-24

1121 Mechanisms associated with pyrethroid resistance in populations of Aedes aegypti (Diptera: Culicidae) from the Caribbean coast of Colombia

Pareja-Loaiza, P. X.; Santacoloma Varon, L.; Rey Vega, G.; Gomez-Camargo, D.; Maestre-Serrano, R.; Lenhart, A.

10.1101/2020.01.23.916577 — zoology — Posted on 2020-01-23

1122 Effects of sustained inflation pressure during neonatal cardiopulmonary resuscitation of asphyxiated piglets

Shim, G.-H.; Kim, S. Y.; Cheung, P.-Y.; Lee, T.-F.; O'Reilly, M.; Schmölzer, G. M.

10.1101/2020.01.23.916544 — scientific communication and education — Posted on 2020-01-23

1123 Stereo-EEG reveals rich cortical dynamics in humans coping with difficult action discrimination.

Platonov, A.; Pelliccia, V.; Sartori, I.; LoRusso, G.; Avanzini, P.; Orban, G. A.

10.1101/2020.01.23.916569 — neuroscience — Posted on 2020-01-23

1124 Diversity increases the stability of ecosystems.

Makse, H. A.; Arese Lucini, F.; Morone, F.; Tomassone, M. S.

10.1101/2020.01.23.916536 — ecology — Posted on 2020-01-23

1125 Genome Wide Identification, Characterization and Expression Analysis of Non-Arginine Aspartate Receptor like kinase gene family in Hot pepper under Colletotrichum truncatum stress conditions

R, S.; MSR, K.; P, S.; R, S. K.; S, K.

10.1101/2020.01.23.916528 — plant biology — Posted on 2020-01-23

1126 Effects of methionine supplementing on intestine, liver and uterus morphology, and on positivity and expression of calbindin-D28k and TRPV6 calcium carriers in laying quails in thermoneutral conditions and under thermal stress

Guerra, R. R.; de Moraes, L. R.; Delicato, M. E. A.; da Silva Cruz, A.; Pereira da Silva, H. T. F. N.; de Vasconcelos Alves, C. V. B.; Campos, D. B.; Saraiva, E. P.; Perazzo da Costa, F. G.

10.1101/2020.01.23.916551 — physiology — Posted on 2020-01-23

1127 Vibrotactile perception in the sole of the foot in people with normal glucose tolerance and type 2 diabetes

Peterson, M.; Pingel, R.; Rolandsson, O.; Dahlin, L. B.

10.1101/522706 — neuroscience — Posted on 2020-01-23

1128 Novel culture method to diagnose fungal infections with biopsy tissues

Zhao, J.; Zhang, Y.; Fan, Y.; Xiong, Z.; Xia, Y.; Zou, X.; Han, J.; Li, B. B.; Wang, C.; Liu, X.; Lu, B.; Cao, B.

10.1101/2020.01.22.916346 — microbiology — Posted on 2020-01-23

1129 Accumulation of ammonium owing to the metabolic imbalance of carbon and nitrogen might inhibit the central metabolism in Methylomonas sp. ZR1

Guo, W.; He, R.; Zhao, Y.; Li, D.

10.1101/2020.01.22.916338 — physiology — Posted on 2020-01-23

1130 A probabilistic functional parcellation of human occipito-temporal cortex

Rosenke, M.; van Hoof, R.; van den Hurk, J.; Goebel, R. W.

10.1101/2020.01.22.916239 — neuroscience — Posted on 2020-01-23

1131 N-3 polyunsaturated fatty acids promote astrocyte differentiation and neurotrophin production independent of cAMP in patient-derived neural stem cells

Yu, J.-Z.; Wang, J.; Sheridan, S.; Perlis, R.; Rasenick, M. M.

10.1101/2020.01.22.916130 — neuroscience — Posted on 2020-01-23

1132 Probing multi-way chromatin interaction with hypergraph representation learning

Zhang, R.; Ma, J.

10.1101/2020.01.22.916171 — bioinformatics — Posted on 2020-01-23

1133 RBMS1 suppresses colon cancer metastasis through targeted stabilization of its mRNA regulon

Yu, J.; Culbertson, B.; Asgharian, H.; Navickas, A.; Fish, L.; Olegario, J. P.; Hanisch, B.; Weinberg, E.; Dienstmann, R.; Warren, R.; Goodarzi, H.

10.1101/2020.01.22.916205 — systems biology — Posted on 2020-01-23

1134 Hierarchical transcriptional regulation of quorum-sensing genes in Vibrio harveyi

Chaparian, R. R.; Ball, A. S.; van Kessel, J. C.

10.1101/2020.01.22.916312 — microbiology — Posted on 2020-01-23

1135 From graph topology to ODE models for gene regulatory networks

Kang, X.; Hajek, B.; Hanzawa, Y.

10.1101/2020.01.22.916114 — bioinformatics — Posted on 2020-01-23

1136 Continuous detection of glucose and insulin in live animals

Poudineh, M.; Maikawa, C. L.; Yue Ma, E.; Pan, J.; Mamerow, D.; Han, Y.; Baker, S. w.; Beirami, A.; Eisenstein, M.; Kim, S.; Vuckovic, J.; Appel, E. A.; Soh, H. T.

10.1101/2020.01.22.916106 — bioengineering — Posted on 2020-01-23

1137 Coordination and assembly of protein complexes encoded across mitochondrial and nuclear genomes is assisted by CLPP2 in Arabidopsis thaliana

Petereit, J.; Duncan, O.; Murcha, M.; Fenske, R.; Cincu, E.; Cahn, J.; Pruzinska, A.; Kollipara, L.; Wortekamp, S.; Sickmann, A.; Lee, J.; Lister, R.; Millar, H.; HUANG, S.

10.1101/2020.01.22.907055 — plant biology — Posted on 2020-01-23

1138 Schistosomes alter expression of immunomodulatory gene products following in vivo praziquantel exposure

McCusker, P.; Rohr, C. M.; Chan, J. D.

10.1101/2020.01.22.915710 — pharmacology and toxicology — Posted on 2020-01-23

1139 Antigens in water-in-oil emulsion: a simple antigen extraction method for analysis and proof of equal antigen distribution in vaccination syringe after mixture

Ghosh, M.; Gauger, M.; Denk, M.; Rammensee, H.-G.; Stevanovic, S.

10.1101/2020.01.22.916189 — pharmacology and toxicology — Posted on 2020-01-23

1140 Strain-dependent inhibition of Clostridioides difficile by commensal Clostridia encoding the bile acid inducible (bai) operon

Reed, A. D.; Nethery, M. A.; Stewart, A.; Barrangou, R.; Theriot, C. M.

10.1101/2020.01.22.916304 — microbiology — Posted on 2020-01-23

1141 InStrain enables population genomic analysis from metagenomic data and rigorous detection of identical microbial strains

Olm, M. R.; Crits-Christoph, A.; Bouma-Gregson, K.; Firek, B.; Morowitz, M.; Banfield, J.

10.1101/2020.01.22.915579 — microbiology — Posted on 2020-01-23

1142 A universal chromosome identification system for maize and wild Zea species

Tomaz Braz, G.; do Vale Martins, L.; Zhang, T.; S. Albert, P.; A. Birchler, J.; Jiang, J.

10.1101/2020.01.22.915942 — genetics — Posted on 2020-01-23

1143 Genomic and phenotypic evolution of Escherichia coli in a novel citrate-only resource environment

Blount, Z. D.; Maddamsetti, R.; Grant, N. A.; Ahmed, S. T.; Jagdish, T.; Sommerfeld, B. A.; Tillman, A.; Moore, J. P.; Slonczewski, J. L.; Barrick, J. E.; Lenski, R. E.

10.1101/2020.01.22.915975 — evolutionary biology — Posted on 2020-01-23

1144 CIRFESS: An interactive resource for querying the set of theoretically detectable peptides for cell surface and extracellular enrichment proteomic studies

Waas, M.; Littrell, J.; Gundry, R. L.

10.1101/2020.01.22.916148 — bioinformatics — Posted on 2020-01-23

1145 Novel Type 2-high gene clusters associated with corticosteroid sensitivity in COPD

Faiz, A.; Pavlidis, S.; Kuo, C.-H. S.; Rowe, A.; Hiemstra, P. S.; Timens, W.; Berg, M.; Wisman, M.; Guo, Y.; Djukanovic, R.; Sterk, P. J.; Nawijn, M. C.; Adcock, I. M.; Chung, K. F.; van den Berge, M.

10.1101/2020.01.22.912022 — bioinformatics — Posted on 2020-01-23

1146 High throughput micro-CT scanning of small fossils: preparation, packing, parameters and post-processing

Hipsley, C. A.; Aguilar, R.; Black, J. R.; Hocknull, S. A.

10.1101/2020.01.22.911875 — evolutionary biology — Posted on 2020-01-23

1147 High-throughput screens of PAM-flexible Cas9 variants for gene knock-out and transcriptional modulation

Legut, M.; Daniloski, Z.; Xue, X.; McKenzie, D.; Guo, X.; Wessels, H.-H.; Sanjana, N. E.

10.1101/2020.01.22.916064 — bioengineering — Posted on 2020-01-23

1148 S-adenosylhomocysteine hydrolase regulates anterior patterning in Dugesia japonica

Reinmets, K.; Bischof, J.; Taketa, E.; Levin, M.; Fuchs, S. M. M.

10.1101/2020.01.22.916072 — physiology — Posted on 2020-01-23

1149 A computational framework for a Lyapunov-enabled analysis of biochemical reaction networks

Ali Al-Radhawi, M.; Angeli, D.; Sontag, E.

10.1101/696716 — systems biology — Posted on 2020-01-23

1150 Implicit adaptation is driven by direct policy updates rather than forward-model-based learning

Hadjiosif, A. M.; Krakauer, J. W.; Haith, A. M.

10.1101/2020.01.22.914473 — neuroscience — Posted on 2020-01-23

1151 Bone morphogenetic protein 4 reduces global H3K4me3 to inhibit proliferation and promote differentiation of human neural stem cells

Nayak, S.; Best, B.; Hayes, E.; Mahenthiran, A.; Wadhwani, N.; Mania-Farnell, B.; Hashizume, R.; Kessler, J.; James, C. D.; Tomita, T.; XI, G.

10.1101/2020.01.22.915934 — neuroscience — Posted on 2020-01-23

1152 A standardized head-fixation system for performing large-scale, in-vivo physiological recordings in mice

Groblewski, P.; Sullivan, D.; Lecoq, J.; de Vries, S.; Caldejon, S.; L'Heureux, Q.; Keenan, T.; Roll, K.; Slaughterback, C.; Williford, A.; Farrell, C.

10.1101/2020.01.22.916007 — neuroscience — Posted on 2020-01-23

1153 The self-face automatically captures attention without consciousness

Bola, M.; Paz, M.; Doradzinska, L.; Nowicka, A.

10.1101/2020.01.22.915595 — neuroscience — Posted on 2020-01-23

1154 Post-transcriptional regulation of aortic calcification in KLOTHO deficient mice: impact of miR-145 and miR-378

Tang, Y.; Shah, T. A.; Yurkow, E. J.; Rogers, M. B.

10.1101/736330 — molecular biology — Posted on 2020-01-23

1155 Microbial competition reduces interaction distances to the low {micro}m-range

van Tatenhove-Pel, R. J.; Rijavec, T.; Lapanje, A.; van Swam, I.; Zwering, E.; Hernandez, J.; Kuipers, O.; Picioreanu, C.; Teusink, B.; Bachmann, H.

10.1101/2020.01.22.915835 — microbiology — Posted on 2020-01-23

1156 Caldicellulosiruptor bescii regulates pilus expression in response to the polysaccharide, xylan

Khan, A. M. A. M.; Hauk, V. J.; Ibrahim, M.; Raffel, T. R.; Blumer-Schuette, S. E.

10.1101/614800 — microbiology — Posted on 2020-01-23

1157 Hidden patterns of codon usage bias across kingdoms

Deng, Y.; de Lima Hedayioglu, F.; Kalfon, J.; Chu, D.; von der Haar, T.

10.1101/478016 — bioinformatics — Posted on 2020-01-23

1158 A Grain of Salt

Houston, K.; Qiu, J.; Wege, S.; Hmrova, M.; Oakey, H.; Qu, Y.; Smith, P.; Situmorang, A.; Macaulay, M.; Flis, P.; Bayer, M.; Roy, S.; Halpin, C.; Russell, J.; Byrt, C.; Gilliham, M. J.; Salt, D. E.; Waugh, R.

10.1101/2020.01.23.916742 — genetics — Posted on 2020-01-23

1159 Practical parameter identifiability for spatiotemporal models of cell invasion

Simpson, M. J.; Baker, r. E.; Vittadello, S. T.; Maclaren, O.

10.1101/839282 — cell biology — Posted on 2020-01-23

1160 AmpliconReconstructor: Integrated analysis of NGS and optical mapping resolves the complex structures of focal amplifications in cancer

Luebeck, J.; Coruh, C.; Dehkordi, S. R.; Lange, J. T.; Turner, K. M.; Deshpande, V.; Pai, D. A.; Zhang, C.; Rajkumar, U.; Law, J. A.; Mischel, P. S.; Bafna, V.

10.1101/2020.01.22.916031 — bioinformatics — Posted on 2020-01-23

1161 The Community Simulator: A Python package for microbial ecology

Marsland, R.; Cui, W.; Goldford, J.; Mehta, P.

10.1101/613836 — ecology — Posted on 2020-01-23

1162 Tough and Tunable Scaffold-Hydrogel Composite Biomaterial for Soft-to-Hard Musculoskeletal Tissue Interfaces

Sun Han Chang, R. A.; Kersh, M. E.; Harley, B.

10.1101/2020.01.22.915850 — bioengineering — Posted on 2020-01-23

1163 Prefrontal deep projection neurons enable cognitive flexibility via persistent feedback monitoring

Spellman, T.; Svei, M.; Liston, C.

10.1101/828590 — neuroscience — Posted on 2020-01-23

1164 The entorhinal cortical alvear pathway differentially excites interneuron subtypes in hippocampal CA1

Bell, K. A.; Delong, R.; Goswamee, P.; McQuiston, A. R.

10.1101/2020.01.22.915876 — neuroscience — Posted on 2020-01-23

1165 The role of HMGB1 in invasive Candida albicans infection

Wang, J.; Wu, C.; Wang, Y.; Chen, C.; Chen, J.; Rao, X.; Sun, H.

10.1101/2020.01.21.914895 — microbiology — Posted on 2020-01-23

1166 Prochlorococcus rely on microbial interactions rather than on chlorotic resting stages to survive long-term stress

Roth-Rosenberg, D.; Aharonovich, D.; Luzzatto-Knaan, T.; Vogts, A.; Zoccarato, L.; Eigemann, F.; Nago, N.; Grossart, H.-P.; Voss, M.; Sher, D. J.

10.1101/657627 — microbiology — Posted on 2020-01-23

1167 Cancer PRSweb - an Online Repository with Polygenic Risk Scores (PRS) for Major Cancer Traits and Their Phenome-wide Exploration in Two Independent Biobanks

Fritsche, L. G.; Patil, S.; Beesley, L. J.; VandeHaar, P.; Salvatore, M.; Peng, R. B.; Taliun, D.; Zhou, X.; Mukherjee, B.

10.1101/2020.01.22.915751 — genetics — Posted on 2020-01-23

1168 Single cell determination of cardiac microtissue structure and function using light sheet microscopy

Turaga, D.; Matthys, O. B.; Hookway, T. A.; Joy, D. A.; Calvert, M.; McDevitt, T. C.

10.1101/2020.01.22.915926 — bioengineering — Posted on 2020-01-23

1169 Membrane-associated α-tubulin is less acetylated in postmortem prefrontal cortex from depressed subjects relative to controls: cytoskeletal dynamics, HDAC6 and depression

Singh, H.; Bhaumik, R.; Chmura, J.; Pandey, G. N.; Rasenick, M. M.

10.1101/2020.01.22.915991 — neuroscience — Posted on 2020-01-23

1170 Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin

Zhou, P.; Yang, X.-L.; Wang, X.-G.; Hu, B.; Zhang, L.; Zhang, W.; Si, H.-R.; Zhu, Y.; Li, B.; Huang, C.-L.; Chen, H.-D.; Chen, J.; Luo, Y.; Guo, H.; Jiang, R.-D.; Liu, M.-Q.; Chen, Y.; Shen, X.-R.; Wang, X.; Zheng, X.-S.; Zhao, K.; Chen, Q.-J.; Deng, F.; Liu, L.-L.; Yan, B.; Zhan, F.-X.; Wang, Y.-Y.; Xiao, G.; Shi, Z.-L.

10.1101/2020.01.22.914952 — microbiology — Posted on 2020-01-23

1171 A motor axonopathy in a mouse model of Duchenne Muscular Dystrophy

Dhindsa, J. S.; McCall, A. L.; Strickland, L. M.; Fusco, A. F.; Kahn, A. F.; Elmallah, M. K.

10.1101/2020.01.22.914614 — neuroscience — Posted on 2020-01-23

1172 Evidence of Absence Regression: A Binomial N-Mixture Model for Estimating Bird and Bat Fatalities at Wind Power Facilities

McDonald, T.; Bay, K.; Studyvin, J.; Leckband, J.; Schorg, A.; McIvor, J.

10.1101/2020.01.21.914754 — ecology — Posted on 2020-01-23

1173 Geometric models for robust encoding of dynamical information into embryonic patterns

Jutras-Dube, L.; El-Sherif, E.; Francois, P.

10.1101/2020.01.21.914598 — biophysics — Posted on 2020-01-23

1174 MACREL: antimicrobial peptide screening in genomes and metagenomes

Santos-Junior, C. D.; Pan, S.; Zhao, X.-M.; Coelho, L. P.

10.1101/2019.12.17.880385 — bioinformatics — Posted on 2020-01-23

1175 Chemical transcription roadblocking for nascent RNA display

Strobel, E. J.; Lis, J. T.; Lucks, J. B.

10.1101/2019.12.26.888743 — biochemistry — Posted on 2020-01-23

1176 Post-transcriptional regulation of aortic calcification in KLOTHO deficient mice: impact of miR-145 and miR-378

Tang, Y.; Shah, T. A.; Yurkow, E. J.; Rogers, M. B.

10.1101/736330 — molecular biology — Posted on 2020-01-23

1177 Establishing Rod-Shape from Spherical, Peptidoglycan-Deficient Bacterial Spores

Zhang, H.; Mulholland, G. A.; Seef, S.; Zhu, S.; Liu, J.; Mignot, T.; Nan, B.

10.1101/818641 — microbiology — Posted on 2020-01-23

Schreiber, S.

10.1101/869073 — ecology — Posted on 2020-01-23

1179 p.E152K-STIM1 mutation deregulates Ca2+ signaling contributing to chronic pancreatitis.

Burgos, M.; Phillipe, R.; Antigny, F.; Buscaglia, P.; Masson, E.; Mukherjee, S.; Dubar, P.; Le Marechal, C.; Campeotto, F.; Lebonvallet, N.; Frieden, M.; Llopis, J.; Domingo, B.; Stathopulos, P. B.; Ikura, M.; Brooks, W.; Guida, W.; Chen, J.-M.; Ferec, C.; Capiod, T.; Mignen, O.

10.1101/2020.01.22.916254 — cell biology — Posted on 2020-01-23

1180 Integrative genomic and epigenomic analyses identify a distinct role of c-Myc and L-Myc for lineage determination in small cell lung cancer

Patel, A. S.; Yoo, S.; Kong, R.; Sato, T.; Fridrikh, M.; Sinha, A.; Nudelman, G.; Powell, C. A.; Beasley, M. B.; Zhu, J.; Watanabe, H.

10.1101/852939 — cancer biology — Posted on 2020-01-23

1181 The lonely fish is not a loner fish: whole-brain mapping reveals abnormal activity in socially isolated zebrafish

Tunbak, H.; Vazquez-Pradam, M.; Ryan, T.; Kampff, A. R.; Dreosti, E.

10.1101/2020.01.22.915520 — neuroscience — Posted on 2020-01-23

1182 Metabolic and Epigenomic Regulation of Th17/Treg Balance by the Polyamine Pathway

Wang, C.; Wagner, A.; Fessler, J.; Avila-Pacheco, J.; Karminski, J.; Thakore, P.; Zaghouani, S.; Pierce, K.; Bod, L.; Schnell, A.; DeTomaso, D.; Ron-Harel, N.; Haigis, M.; Puleston, D.; Pearce, E.; Soleimani, M.; Sobel, R.; Clish, C.; Regev, A.; Yosef, N.; Kuchroo, V.

10.1101/2020.01.23.911966 — immunology — Posted on 2020-01-23

1183 Associations between aversive learning processes and transdiagnostic psychiatric symptoms revealed by large-scale phenotyping

Wise, T.; Dolan, R. J.

10.1101/843045 — neuroscience — Posted on 2020-01-23

1184 Dietary supplementation with PUFAs rescues the eggshell defects caused by seipin mutations in C. elegans

Bai, X.; Huang, L.-J.; Chen, S.-W.; Nebenfuehr, B.; Wysolmerski, B.; Wu, J.-C.; Olson, S. K.; Golden, A.; Wang, C.-W.

10.1101/2020.01.23.916718 — cell biology — Posted on 2020-01-23

1185 The C-terminal RRM/ACT domain is crucial for fine-tuning the activation of 'long' RelA-SpoT Homolog enzymes by ribosomal complexes

Takada, H.; Roghanian, M.; Murina, V.; Dzhygyr, I.; Murayama, R.; Akanuma, G.; Atkinson, G. C.; Garcia-Pino, A.; Hauryliuk, V.

10.1101/849810 — biochemistry — Posted on 2020-01-23

1186 Cultural evolution by capital accumulation

Andre, J.-B.; Baumard, N.

10.1101/707620 — evolutionary biology — Posted on 2020-01-23

1187 Failure to maternally reprogram histone methylation causes developmental delay due to germline transcription in somatic tissues

Carpenter, B. S.; Lee, T. W.; Plott, C. F.; Brockett, J. S.; Katz, D.

10.1101/2020.01.22.914580 — developmental biology — Posted on 2020-01-23

1188 Virtual-freezing fluorescence imaging flow cytometry

Mikami, H.; Kawaguchi, M.; Huang, C.-J.; Matsumura, H.; Sugimura, T.; Huang, K.; Lei, C.; Ueno, S.; Miura, T.; Ito, T.; Nagasawa, K.; Maeno, T.; Watarai, H.; Yamagishi, M.; Uemura, S.; Ohnuki, S.; Ohya, Y.; Kurokawa, H.; Matsusaka, S.; Sun, C.-W.; Ozeki, Y.; Goda, K.

10.1101/2020.01.23.916452 — cell biology — Posted on 2020-01-23

1189 TopicNet: a framework for measuring transcriptional regulatory network change

Lou, S.; Li, T.; Kong, X.; Zhang, J.; Liu, J.; Lee, D.; Gerstein, M.

10.1101/862177 — bioinformatics — Posted on 2020-01-23

1190 Substrate Channeling via a Transient Protein-Protein Complex: The case of D-Glyceraldehyde-3-Phosphate Dehydrogenase and L-Lactate Dehydrogenase

Svedruzic, Z. M.; Odorcic, I.; Chang, C. H.; Svedruzic, D.

10.1101/2020.01.22.916023 — biochemistry — Posted on 2020-01-23

1191 A Consensus Proteomic Analysis of Alzheimer's Disease Brain and Cerebrospinal Fluid Reveals Early Changes in Energy Metabolism Associated with Microglia and Astrocyte Activation

Johnson, E.; Dammer, E. B.; Duong, D. M.; Ping, L.; Zhou, M.; Yin, L.; Higginbotham, L. A.; Guajardo, A.; White, B.; Troncoso, J. C.; Thambisetty, M.; Montine, T. J.; Lee, E. B.; Trojanowski, J. Q.; Beach, T. G.; Reiman, E. M.; Haroutunian, V.; Wang, M.; Schadt, E.; Zhang, B.; Dickson, D. W.; Ertekin-Taner, N.; Golde, T. E.; Petyuk, V. A.; De Jager, P. L.; Bennett, D. A.; Wingo, T. S.; Rangaraju, S.; Hajjar, I.; Shulman, J. M.; Lah, J. J.; Levey, A. I.; Seyfried, N. T.

10.1101/802959 — systems biology — Posted on 2020-01-23

1192 Fusion of Drosophila oocytes with specified germline sister cells

Ali-Murthy, Z.; Fetter, R. D.; Kornberg, T. B.

10.1101/2020.01.22.915736 — developmental biology — Posted on 2020-01-23

1193 Dopamine transporter trafficking and Rit2 GTPase: In vivo impact and mechanism of action

Fagan, R. R.; Kearney, P. J.; Sweeney, C. G.; Luethi, D.; Schoot Uiterkamp, F. E.; Schicker, K.; O'Connor, L. C.; Sitte, H. H.; Melikian, H. E.

10.1101/712448 — neuroscience — Posted on 2020-01-23

1194 High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human embryonic stem cell gastruloid cultures

Minn, K. T.; Fu, Y. C.; He, S.; George, S. C.; Anastasio, M. A.; Morris, S. A.; Solnica-Krezel, L.

10.1101/2020.01.22.915777 — developmental biology — Posted on 2020-01-23

1195 Wnt signaling determines body axis polarity in regenerating Hydra tissue

Wang, R.; Steele, R.; Collins, E.-M.

10.1101/2020.01.22.915702 — developmental biology — Posted on 2020-01-23

1196 Prolonged disturbance of proteostasis induces cellular senescence via temporal mitochondrial dysfunction and enhanced mitochondrial biogenesis in human fibroblasts

Takenaka, Y.; Inoue, I.; Nakano, T.; Ikeda, M.; Kakinuma, Y.

10.1101/2020.01.22.916221 — cell biology — Posted on 2020-01-23

1197 CTP synthase forms cytoophidia in archaea

Zhou, S.; Xiang, H.; Liu, J.-L.

10.1101/830091 — cell biology — Posted on 2020-01-23

1198 Unacylated ghrelin and AZP531 suppress the 3D growth of breast cancers

Au, C. C.; Furness, J. B.; Britt, K.; Oshchepkova, S.; Ladumor, H.; Soo, K. Y.; Callaghan, B.; Gerard, C.; Inghirami, G.; Mittal, V.; Wang, Y.; Huang, X.-Y.; Spector, J. A.; Andreopoulou, E.; Zumbo, P.; Betel, D.; Dow, L. E.; Brown, K. A.

10.1101/2020.01.22.915744 — cancer biology — Posted on 2020-01-23

1199 Single-molecule orientation localization microscopy for resolving structural heterogeneities within amyloid fibrils

Ding, T.; Wu, T.; Mazidi, H.; Zhang, O.; Lew, M. D.

10.1101/2020.01.22.916122 — biophysics — Posted on 2020-01-23

1200 Biophotons: low signal/noise ratio reveals crucial events

Benfatto, M.; Pace, E.; Curceanu, C.; Scordo, A.; Clozza, A.; Davoli, I.; Lucci, M.; Francini, R.; De Matteis, F.; Grandi, M.; Tuladhar, R.; Grigolini, P.

10.1101/558353 — biophysics — Posted on 2020-01-23

1201 A Highly Selective Chemical Probe for Activin Receptor-like Kinases ALK4 and ALK5

Hanke, T.; Wong, J. F.; Berger, B.-T.; Abdi, I.; Berger, L. M.; Tesch, R.; Tredup, C.; Bullock, A. N.; Mueller, S.; Knapp, S.

10.1101/2020.01.23.916502 — biochemistry — Posted on 2020-01-23

1202 Allele mining unlocks the identification of RYMV resistance genes and alleles in African cultivated rice.

Pidon, H.; Cheron, S.; Ghesquiere, A.; Albar, L.

10.1101/2020.01.22.914143 — plant biology — Posted on 2020-01-23

1203 Ginseng Ameliorates Effect of Prolonged Use of Omeprazole in Rat Renal Cortex through Decreasing Inflammation, Fibrosis and Apoptosis

Abdel Dayem, D. A. M.; Saied, A.; Ali, A.; El-Tahawy, N.

10.1101/2020.01.22.915587 — pathology — Posted on 2020-01-23

1204 Ketamine blocks the correlation between morphine-induced conditioned place preference and anxiety-like behaviors in mice.

Jones, H.; McKendrick, G.; Garrett, H.; McDevitt, D. S.; Sharma, S.; Silberman, Y.; Graziane, N. M.

10.1101/2020.01.22.915728 — neuroscience — Posted on 2020-01-23

1205 Potential depression and antidepressant-response biomarkers in human lymphoblast cell lines from treatment-responsive and treatment-resistant subjects: roles of SSRIs and omega-3 polyunsaturated fatty acids

Chukaew, P.; Leow, A.; Saengsawang, W.; Rasenick, M. M.

10.1101/2020.01.22.914358 — neuroscience — Posted on 2020-01-23

1206 Epigenetic gene-expression links heart failure to memory impairment

Islam, M. R.; Lbik, D.; Sakib, M. S.; Hofmann, R. M.; Berulava, T.; Mausbach, M. J.; Cha, J.; Vakhtang, E.; Schiffmann, C.; Zieseniss, A.; Katschinski, D. M.; Sananbenesi, F.; Toischer, K.; Fischer, A.

10.1101/2020.01.22.915637 — neuroscience — Posted on 2020-01-23

1207 A defect in thymic tolerance causes T cell-mediated autoimmunity in a murine model of COPA syndrome

Deng, Z.; Law, C. S.; Ho, F. O.; Wang, K. M.; Jones, K. D.; Shin, J.-S.; Shum, A. K.

10.1101/2020.01.21.914440 — immunology — Posted on 2020-01-23

1208 Characterization of mating type genes in heterothallic Neonectria species with emphasis on N. coccinea, N. ditissima, and N. faginata

Stauder, C. M.; Garnas, J. R.; Morrison, E. W.; Salgado-Salazar, C.; Kasson, M. T.

10.1101/2020.01.22.915686 — microbiology — Posted on 2020-01-23

1209 Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection

Batista, S. J.; Still, K. M.; Johanson, D.; Thompson, J. A.; O'Brien, C. A.; Lukens, J. R.; Harris, T.

10.1101/2020.01.22.915652 — immunology — Posted on 2020-01-23

1210 Connectomics analysis reveals first, second, and third order thermosensory and hygrosensory neurons in the adult Drosophila brain

Marin, E. C.; Roberts, R. J. V.; Büld, L.; Theiss, M.; Pleijzier, M. W.; Sarkissian, T.; Laursen, W. J.; Turnbull, R. G.; Schlegel, P.; Bates, A. S.; Li, F.; Landgraf, M.; Costa, M.; Bock, D. D.; Garrity, P. A.; Jefferis, G. S. X. E.

10.1101/2020.01.20.912709 — neuroscience — Posted on 2020-01-23

1211 Cerebellar and Prefrontal-Cortical Engagement During Higher-Order Rule Learning in Older Adulthood

Jackson, T. B.; Maldonado, T.; Eakin, S.; Orr, J. M.; Bernard, J. A.

10.1101/2020.01.22.914739 — neuroscience — Posted on 2020-01-23

1212 Age differences in retrieval-related reinstatement reflect age-related dedifferentiation at encoding

Hill, P. F.; King, D. R.; Rugg, M. D.

10.1101/2020.01.21.912089 — neuroscience — Posted on 2020-01-23

1213 An enhanced characterization of the human skin microbiome: a new biodiversity of microbial interactions

Emiola, A.; Zhou, W.; Oh, J.

10.1101/2020.01.21.914820 — microbiology — Posted on 2020-01-23

1214 Novel ionophores active against La Crosse virus identified through rapid antiviral screening

Sandler, Z. J.; Vu, M. N.; Menachery, V. D.; Mounce, B. C.

10.1101/2020.01.21.914929 — microbiology — Posted on 2020-01-23

1215 A near-term iterative forecasting system successfully predicts reservoir hydrodynamics and partitions uncertainty

Thomas, R. Q.; Figueiredo, R. J.; Daneshmand, V.; Bookout, B. J.; Puckett, L. K.; Carey, C. C.

10.1101/2020.01.22.915538 — ecology — Posted on 2020-01-23

1216 Prepronociceptin expressing neurons in the extended amygdala encode and promote rapid arousal responses to motivationally salient stimuli

Rodriguez-Romaguera, J.; Ung, R.; Nomura, H.; Otis, J.; Basiri, M.; Namboodiri, V.; Zhu, X.; Robinson, E.; McHenry, J.; Kosyk, O.; Jhou, T.; Kash, T.; Bruchas, M.; Stuber, G.

10.1101/2020.01.21.914341 — neuroscience — Posted on 2020-01-23

1217 Local translation in perisynaptic astrocytic processes is specific and regulated by fear conditioning

Mazare, N.; Oudart, M.; Moulard, J.; Cheung, G.; Tortuyaux, R.; Mailly, P.; Mazaud, D.; BEMELMANS, A.-P.; Boulay, A.-C.; Blugeon, C.; Jourdren, L.; Le Crom, S.; Rouach, N.; Cohen-Salmon, M.

10.1101/2020.01.21.913970 — neuroscience — Posted on 2020-01-23

1218 Anillin propels myosin-independent constriction of actin rings

Kucera, O.; Janda, D.; Siahaan, V.; Dijkstra, S. H.; Pilatova, E.; Zatecka, E.; Diez, S.; Braun, M.; Lansky, Z.

10.1101/2020.01.22.915256 — cell biology — Posted on 2020-01-23

1219 Structured clustering of the glycosphingolipid GM1 is required for membrane curvature induced by cholera toxin

Kabbani, A. M.; Raghunathan, K.; Lencer, W. I.; Kenworthy, A. K.; Kelly, C. V.

10.1101/2020.01.22.915249 — biophysics — Posted on 2020-01-23

1220 Modelling the Putative Ancient Distribution of the Costal Rock Pool Mosquito Aedes togoi

Peach, D. A.; Matthews, B. J.

10.1101/2020.01.21.914838 — zoology — Posted on 2020-01-23

1221 Abuse among elderly living in old age homes of Pokhara Lekhnath Metropolitan City:A cross sectional study

Adhikari Baral, M.; Baral, P.; K.C, B.

10.1101/771311 — scientific communication and education — Posted on 2020-01-23

1222 Role of the medial prefrontal cortex in the effects of rapid acting antidepressants on affective biases in a rodent decision-making task

Hales, C. A.; Bartlett, J.; Arban, R.; Hengerer, B.; Robinson, E. S.

10.1101/2020.01.22.915132 — neuroscience — Posted on 2020-01-23

1223 ER stress in the dorsal root ganglia regulates BK channel physiology and contributes to pain hypersensitivity in a mouse model of multiple sclerosis

Yousuf, M. S.; Samtleben, S.; Lamothe, S. M.; Friedman, T.; Catuneanu, A.; Thorburn, K.; Desai, M.; Tenorio, G.; Schenk, G. J.; Ballanyi, K.; Kurata, H. T.; Simmen, T.; Kerr, B. J.

10.1101/2020.01.22.915546 — neuroscience — Posted on 2020-01-23

1224 TMSNP: a web server to predict pathogenesis of missense mutations in transmembrane region of membrane proteins

Garcia-Recio, A.; Gomez-Tamayo, J. C.; Campillo, M.; Cordomi, A.; Olivella, M.

10.1101/2020.01.21.913764 — bioinformatics — Posted on 2020-01-23

Wu, C. M.; Schulz, E.; Garvert, M. M.; Meder, B.; Schuck, N. W.

10.1101/2020.01.21.914556 — animal behavior and cognition — Posted on 2020-01-23

1226 Shared and specific signatures of locomotor ataxia in mutant mice

Machado, A. S.; Marques, H. G.; Duarte, D. F.; Darmohray, D. M.; Carey, M. R.

10.1101/2020.01.21.914077 — neuroscience — Posted on 2020-01-23

1227 Visual and oculomotor abilities predict professional baseball batting performance

Liu, S.; Edmunds, F. R.; Burris, K.; Appelbaum, L. G.

10.1101/2020.01.21.913152 — neuroscience — Posted on 2020-01-23

1228 Privacy-preserving biomedical database queries with optimal privacy-utility trade-offs

Cho, H.; Simmons, S.; Kim, R.; Berger, B.

10.1101/2020.01.16.909010 — bioinformatics — Posted on 2020-01-23

1229 Early metazoan origin and multiple losses of a novel clade of RIM pre-synaptic calcium channel scaffolding protein homologues

Piekut, T.; Wong, Y. Y.; Walker, S. E.; Smith, C. L.; Gauberg, J.; Harracksingh, A. N.; Lowden, C.; Cheng, H.-Y. M.; Spencer, G. E.; Senatore, A.

10.1101/2020.01.14.906610 — evolutionary biology — Posted on 2020-01-23

1230 The rebound response plays a role in the motion mechanisms and perception

Cohen-Duwek, H.; Spitzer, H.

10.1101/2019.12.31.891580 — neuroscience — Posted on 2020-01-23

1231 Evolution of the insecticide target Rdl in African Anopheles is driven by interspecific andinterkaryotypic introgression

Grau-Bove, X.; Tomlinson, S.; O'Reilly, A. O.; Harding, N. J.; Miles, A.; Kwiatkowski, D.; Donnelly, M. J.; Weetman, D.; The Anopheles gambiae 1000 Genomes Consortium,

10.1101/2019.12.17.879775 — evolutionary biology — Posted on 2020-01-23

1232 The conservation status and population decline of the African penguin deconstructed in space and time

Sherley, R. B.; Crawford, R. J. M.; de Blocq, A. D.; Dyer, B. M.; Geldenhuys, D.; Hagen, C.; Kemper, J.; Makhado, A. B.; Pichegru, L.; Upfold, L.; Visagie, J.; Waller, L. J.; Winker, H.

10.1101/2020.01.15.907485 — ecology — Posted on 2020-01-23

1233 Quantification of guanosine tetraphosphate and other nucleotides in plants and algae using stable isotope-labelled internal standards.

Bartoli, J.; Citerne, S.; Mouille, G.; Bouveret, E.; Field, B.

10.1101/2019.12.13.875492 — plant biology — Posted on 2020-01-23

1234 Genome-wide functional analysis of hot pepper immune receptors reveals an autonomous NLR cluster in seed plants

Lee, H.-Y.; Mang, H.; Seo, Y.-E.; Kim, M.-S.; Oh, S.; Kim, S.-B.; Choi, D.

10.1101/2019.12.16.878959 — plant biology — Posted on 2020-01-23

1235 Reduction of auditory input improves performance on the heartbeat tracking task, but does not necessarily enhance interoception

Todd, J.; Hina, F.; Aspell, J. E.

10.1101/830141 — neuroscience — Posted on 2020-01-23

1236 A dynamic normalization model of temporal attention

Denison, R. N.; Carrasco, M.; Heeger, D. J.

10.1101/2019.12.21.886051 — neuroscience — Posted on 2020-01-23

1237 Probabilistic gene expression signatures identify cell-types from single cell RNA-seq data

Grabski, I. N.; Irizarry, R. A.

10.1101/2020.01.05.895441 — genomics — Posted on 2020-01-23

1238 Computational estimates of mechanical constraints on cell migration through the extracellular matrix

Maxian, O.; Mogilner, A.; Strychalski, W.

10.1101/2020.01.19.912006 — cell biology — Posted on 2020-01-23

1239 Chaperonin Abundance Boosts Bacterial Fitness

Kumar, S. C. M.; Chugh, K.; Dutta, A.; Mahamkali, V.; Bose, T.; Mande, S. S.; mande, s.; Lund, P. A.

10.1101/2019.12.31.891820 — biochemistry — Posted on 2020-01-23

1240 Cryo-EM structures of cardiac thin filaments reveal the 3D architecture of troponin.

Oda, T.; Yanagisawa, H.; Wakabayashi, T.

10.1101/2020.01.15.908418 — biochemistry — Posted on 2020-01-23

1241 A Consensus Proteomic Analysis of Alzheimer's Disease Brain and Cerebrospinal Fluid Reveals Early Changes in Energy Metabolism Associated with Microglia and Astrocyte Activation

10.1101/802959 — systems biology — Posted on 2020-01-23

1242 Hallmarks of frailty and osteosarcopenia in prematurely aged PolgAD257A/D257A mice

Scheuren, A. C.; D'Hulst, G.; Kuhn, G. A.; Masschelein, E.; Wehrle, E.; De Bock, K.; Müller, R.

10.1101/758243 — physiology — Posted on 2020-01-23

1243 THE EFFECT OF SCANNING SPEED ON TEXTURE-ELICITED VIBRATIONS

Greenspon, C.; McLellan, K.; Lieber, J. D.; Bensmaia, S. J.

10.1101/680322 — neuroscience — Posted on 2020-01-23

1244 Attentional Modulation of the Auditory Steady-State Response across the Cortex

Manting, C. L.; Andersen, L. M.; Gulyas, B.; Ullen, F.; Lundqvist, D.

10.1101/836031 — neuroscience — Posted on 2020-01-23

1245 TNF receptor associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation

Semmler, S.; Gagne, M.; Garg, P.; Pickles, S. R.; Baudouin, C.; Hamon-Keromen, E.; Destroismaisons, L.; Khalfallah, Y.; Chaineau, M.; Caron, E.; Bayne, A. N.; Trempe, J.-F.; Cashman, N. R.; Star, A. T.; Haqqani, A. S.; Durcan, T. M.; Meiering, E. M.; Robertson, J.; Grandvaux, N.; Plotkin, S. S.; McBride, H. M.; Vande Velde, C.

10.1101/780460 — neuroscience — Posted on 2020-01-23

1246 Novel target identification using single cell sequencing and electrophysiology of cardiac sympathetic neurons in disease

Davis, H.; Herring, N.; Paterson, D. J.

10.1101/2019.12.11.872580 — neuroscience — Posted on 2020-01-23

1247 DNB-Based On-Chip Motif Finding (DocMF): a High-Throughput Method to Profile Different Types of Protein-DNA Interactions

Li, Z.; Wang, X.; Xu, D.; Zhang, D.; Wang, D.; Dai, X.; Wang, Q.; Li, Z.; Gu, Y.; Ouyang, W.; Zhao, S.; Huang, B.; Gong, J.; Zhao, J.; Chen, A.; Shen, Y.; Dong, Y.; Zhang, W.; Xu, X.; Xu, C.; Jiang, Y.; Xu, X.

10.1101/827428 — molecular biology — Posted on 2020-01-23

1248 Real-time sampling of travelers shows intestinal colonization by multidrug-resistant bacteria to be a dynamic process with multiple transient acquisitions

Kantele, A.; Kuenzli, E.; Dunn, S. J.; Dance, D. A.; Newton, P. N.; Davong, V.; Mero, S.; Pakkanen, S.; Neumayr, A.; Hatz, C.; Snaith, A.; Kallonen, T.; Corander, J.; McNally, A.

10.1101/827915 — microbiology — Posted on 2020-01-23

1249 TNFRSF14 (HVEM) is a novel immune checkpoint blockade that can be targeted by a monoclonal antibody to improve anti-tumor immunity in humanized mice

Brunel, S.; Aubert, N.; Olive, D.; marodon, g.

10.1101/711119 — immunology — Posted on 2020-01-23

1250 Derivation and characterization of chimera-competent eXtra-Embryonic eNdoderm 1 (XEN) cells from pig blastocysts

Telugu, B.; Park, C. H.; Jeoung, Y. H.; Uh, J.; Park, K. E.; Bridge, J.; Powells, A.; Li, J.; Pence, L.; Liu, T.; Sun, H.-X.; Gu, Y.; Shen, Y.; Wu, J.; Izpisua Belmonte, J. C.

10.1101/2020.01.02.892802 — developmental biology — Posted on 2020-01-23

1251 Geometric models for robust encoding of dynamical information into embryonic patterns

Jutras-Dube, L.; El-Sherif, E.; Francois, P.

10.1101/2020.01.21.914598 — biophysics — Posted on 2020-01-23

1252 Supra-molecular assemblies of ORAI1 at rest precede local accumulation into punctae after activation

Peckys, D. B.; Alansary, D.; Niemeyer, B. A.; de Jonge, N.

10.1101/2020.01.13.903856 — biophysics — Posted on 2020-01-23

1253 Survey of metaproteomics software tools for functional microbiome analysis.

Sajulga, R.; Easterly, C.; Riffle, M.; Mesuere, B.; Muth, T.; Mehta, S.; Kumar, P.; Johnson, J.; Gruening, B. A.; Schiebenhoefer, H.; Kolmeder, C.; Fuchs, S.; Nunn, B.; Rudney, J.; Griffin, T.; Jagtap, P.

10.1101/2020.01.07.897561 — bioinformatics — Posted on 2020-01-23

1254 Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism

Ramaswami, G.; Won, H.; Gandal, M. J.; Haney, J.; Wang, J. C.; Wong, C. C. Y.; Sun, W.; Prabhakar, S.; Mill, J.; Geschwind, D. H.

10.1101/718932 — genomics — Posted on 2020-01-23

1255 Lipid droplet biogenesis is driven by a liquid-liquid phase separation.

Zoni, V.; Khaddaj, R.; Campomanes, P.; Thiam, A. R.; Schneiter, R.; Vanni, S.

10.1101/777466 — cell biology — Posted on 2020-01-23

1256 chromoMap: An R package for Interactive Visualization and Annotation of Chromosomes

Anand, L.; Rodriguez Lopez, C. M.

10.1101/605600 — bioinformatics — Posted on 2020-01-23

1257 The role of evolving interfacial substrate properties on heterogeneous cellulose hydrolysis kinetics

Nill, J. D.; Jeoh, T.

10.1101/691071 — bioengineering — Posted on 2020-01-23

1258 The YdiU Domain Modulates Bacterial Stress Signaling through Mn2+-dependent UMPylation

Yang, Y.; Yue, Y.; Song, N.; Li, C.; Yuan, Z.; Wang, Y.; Ma, Y.; Li, H.; Zhang, F.; Wang, W.; Jia, H.; Li, P.; Li, X.; Wang, Q.; Ding, Z.; Dong, H.; Gu, L.; li, b.

10.1101/692707 — biochemistry — Posted on 2020-01-23

1259 Pectin methylesterase selectively softens the onion epidermal wall yet reduces acid-induced creep

Wang, X.; Wilson, L.; Cosgrove, D. J.

10.1101/766931 — plant biology — Posted on 2020-01-23

1260 Parietal Cortex Integrates Object Orientation and Saccade Signals to Update Grasp Plans

Baltaretu, B. R.; Monaco, S.; Velji-Ibrahim, J.; Luabeya, G. N.; Crawford, J. D.

10.1101/758532 — neuroscience — Posted on 2020-01-23

1261 Face Selective Neural Activity: Comparison Between Fixed and Free Viewing

Auerbach-Asch, C. R.; Bein, O.; Deouell, L. Y.

10.1101/748756 — neuroscience — Posted on 2020-01-23

1262 Intersubject consistent dynamic connectivity during natural vision revealed by functional MRI

Di, X.; Biswal, B. B.

10.1101/796433 — neuroscience — Posted on 2020-01-23

1263 Post-transcriptional regulation of aortic calcification in KLOTHO deficient mice: impact of miR-145 and miR-378

Tang, Y.; Shah, T. A.; Yurkow, E. J.; Rogers, M. B.

10.1101/736330 — molecular biology — Posted on 2020-01-23

1264 Phylogenomics of expanding uncultured environmental Tenericutes provides insights into their pathogenicity and evolutionary relationship with Bacilli

Wang, Y.; Huang, J.-M.; Zhou, Y.-L.; Almeida, A.; Finn, R. D.; Danchin, A.; He, L.-S.

10.1101/2020.01.21.914887 — microbiology — Posted on 2020-01-23

1265 Self-reported Health is Related to Body Height and Waist Circumference in Rural Indigenous and Urbanised Latin-American Populations

Leongomez, J. D.; Sanchez, O. R.; Vasquez-Amezquita, M.; Valderrama, E.; Castellanos-Chacon, A.; Morales-Sanchez, L.; Nieto, J.; Gonzalez-Santoyo, I.

10.1101/562942 — evolutionary biology — Posted on 2020-01-23

1266 Postpartum breast cancer progression is driven by semaphorin 7a mediated invasion and survival

Tarullo, S.; Hill, R.; Hansen, K.; Behbod, F.; Borges, V. F.; Nelson, A.; Lyons, T. R.

10.1101/631044 — cancer biology — Posted on 2020-01-23

1267 FINET: Fast Inferring NETwork

WANG, A.; HAI, R.

10.1101/733683 — bioinformatics — Posted on 2020-01-23

1268 Large prospective losses lead to sub-optimal sensorimotor decisions in humans

Adkins, T. J.; Lewis, R. L.; Lee, T. G.

10.1101/406439 — animal behavior and cognition — Posted on 2020-01-23

1269 A Bayesian and efficient observer model explains concurrent attractive and repulsive history biases in visual perception

Fritsche, M.; Spaak, E.; de Lange, F. P.

10.1101/2020.01.22.915553 — neuroscience — Posted on 2020-01-23

1270 Automatic Three-Dimensional Reconstruction of Fascicles in Peripheral Nerves from Histological Images

Tovbis, D.; Zariffa, J.; Agur, A.; Mogk, J. P.

10.1101/2020.01.22.913251 — neuroscience — Posted on 2020-01-23

1271 Distinct sensorimotor feedback loops for dynamic and static control of primate precision grip

Oya, T.; Takei, T.; Seki, K.

10.1101/640201 — neuroscience — Posted on 2020-01-23

1272 Separable, Ctf4-mediated recruitment of DNA Polymerase α for initiation of DNA synthesis at replication origins and lagging-strand priming during replication elongation

Porcella, S. Y.; Koussa, N. C.; Tang, C. P.; Kramer, D. N.; Srivastava, P.; Smith, D. J.

10.1101/352567 — molecular biology — Posted on 2020-01-23

1273 A novel strategy for single-cell metabolic analysis highlights dynamic changes in immune subpopulations

Ahl, P. J.; Hopkins, R. A.; Xiang, W. W.; Au, B.; Kaliaperumal, N.; Fairhurst, A.-M.; Connolly, J. E.

10.1101/2020.01.21.914663 — immunology — Posted on 2020-01-23

1274 Synthetic mycobacterial molecular patterns partially complete Freund's adjuvant

Dube, J.-Y.; McIntosh, F.; Zarruk, J. G.; David, S.; Nigou, J.; Behr, M. A.

10.1101/699165 — immunology — Posted on 2020-01-23

1275 Accurate CNV identification from only a few cells with low GC bias in a single-molecule sequencing platform

HU, L.; LIN, Q.; XIE, P.; ZENG, L.; LIU, L.; HUANG, M.; YAN, Q.; Zhang, M.; LIN, G.

10.1101/2020.01.21.908897 — genetics — Posted on 2020-01-23

1276 STAGdb: a 30K SNP genotyping array and Science Gateway for Acropora corals and their dinoflagellate symbionts

Kitchen, S. A.; Von Kuster, G.; Vasquez Kuntz, K. L.; Reich, H. G.; Miller, W.; Griffin, S.; Fogarty, N. D.; Baums, I.

10.1101/2020.01.21.914424 — genetics — Posted on 2020-01-23

1277 Intuitive and broadly applicable definitions of niche and fitness differences

Spaak, J. W.; DeLaender, F.

10.1101/482703 — ecology — Posted on 2020-01-23

1278 The Degradation-promoting Roles of Deubiquitinases Ubp6 and Ubp3 in Cytosolic and ER Protein Quality Control

Wu, H.; Ng, D. T. W.; Cheong, I.; Matsudaira, P.

10.1101/2020.01.22.915793 — cell biology — Posted on 2020-01-23

1279 A reference single-cell transcriptomic atlas of human skeletal muscle tissue reveals bifurcated muscle stem cell populations

De Micheli, A. J.; Spector, J. A.; Elemento, O.; Cosgrove, B. D.

10.1101/2020.01.21.914713 — cell biology — Posted on 2020-01-23

1280 Automated Workflow For Peptide-level Quantitation From DIA/ SWATH-MS Data

Gupta, S.; Rost, H.

10.1101/2020.01.21.914788 — bioinformatics — Posted on 2020-01-23

1281 BATMAN: fast and accurate integration of single-cell RNA-Seq datasets via minimum-weight matching

Mandric, I.; Hill, B.; Freund, M. K.; Thompson, M.; Halperin, E.

10.1101/2020.01.22.915629 — bioinformatics — Posted on 2020-01-23

1282 BACTERIAL GROWTH INDUCED BIOCEMENTATION TECHNOLOGY, 'SPACE BRICK' - A PROPOSAL FOR EXPERIMENT AT MICROGRAVITY AND PLANETARY ENVIRONMENTS

Kumar, A.; Dikshit, R.; Gupta, N.; Jain, A.; Dey, A.; Nandi, A.; Venugopal, I.; Viswanathan, K.; Sridhara, N.; Rajendra, A.

10.1101/2020.01.22.914853 — bioengineering — Posted on 2020-01-23

1283 APPLICATION OF PETRI NETS METHODOLOGY FOR THE EXAMINATION OF THE BIO(PHYSICO)CHEMICAL PARAMETERS OF MITOCHONDRIA FUNCTIONING

Danylovych, H.; Chunikhin, A. Y.; Danylovych, Y.; Kosterin, S. O.

10.1101/2020.01.22.915074 — biochemistry — Posted on 2020-01-23

1284 Utilizing top-down hyperspectral imaging for monitoring genotype and growth conditions in maize

Tirado, S. B.; St Dennis, S.; Enders, T. A.; Springer, N. M.

10.1101/2020.01.21.914069 — plant biology — Posted on 2020-01-23

1285 Heme Impairs Alveolar Epithelial Sodium Channels Post Toxic Gas Inhalation

Aggarwal, S.; Lazrak, A.; Ahmad, I.; Yu, Z.; Bryant, A.; Mobley, J.; Ford, D.; Matalon, S.

10.1101/2020.01.22.909879 — physiology — Posted on 2020-01-23

1286 Neuroligin3 Splice Isoforms Shape Mouse Hippocampal Inhibitory Synaptic Function

Uchigashima, M.; Leung, M.; Watanabe, T.; Cheung, A.; Watanabe, M.; Imamura Kawasawa, Y.; Futai, K.

10.1101/2020.01.22.915801 — neuroscience — Posted on 2020-01-23

1287 GPCR-mediated clearance of tau in post-synaptic compartments attenuates tau pathology in vivo

Myeku, N.; Schaler, A. W.; Runyan, A. M.; Fowler, S. L.; Figueroa, H. Y.; Shioda, S.; Santa Maria, I.; Duff, K. E.

10.1101/2020.01.21.914135 — neuroscience — Posted on 2020-01-23

1288 Speech-in-noise detection is related to auditory working memory precision for frequency

Lad, M.; Holmes, E.; Chu, A.; Griffiths, T. D.

10.1101/2020.01.22.915165 — neuroscience — Posted on 2020-01-23

1289 A motor axonopathy in a mouse model of Duchenne Muscular Dystrophy

Dhindsa, J. S.; McCall, A. L.; Strickland, L. M.; Fusco, A. F.; Kahn, A. F.; Elmallah, M. K.

10.1101/2020.01.22.914614 — neuroscience — Posted on 2020-01-23

1290 Linguistic input drives brain network configuration during language comprehension.

Quinones, I.; Molinaro, N.; Caballero Gaudes, C.; Mancini, S.; Hernandez-Cabrera, J. A.; Barber, H.; Carreiras, M.

10.1101/2020.01.22.915041 — neuroscience — Posted on 2020-01-23

1291 Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin

Shi, Z.-L.; Zhou, P.; Yang, X.-L.; Wang, X.-G.; Hu, B.; Zhang, L.; Zhang, W.; Si, H.-R.; Zhu, Y.; Li, B.; Huang, C.-L.; Chen, H.-D.; Chen, J.; Luo, Y.; Guo, H.; Jiang, R.-D.; Liu, M.-Q.; Chen, Y.; Shen, X.-R.; Wang, X.; Zheng, X.-S.; Zhao, K.; Chen, Q.-J.; Deng, F.; Liu, L.-L.; Yan, B.; Zhan, F.-X.; Wang, Y.-Y.; Xiao, G.

10.1101/2020.01.22.914952 — microbiology — Posted on 2020-01-23

1292 Structural insight into tanapoxvirus mediated inhibition of apoptosis

Suraweera, C. D.; Anasir, M. I.; Chugh, S.; Javorsky, A.; Impey, R. E.; Hasan Zadeh, M.; Soares da Costa, T. P.; Hinds, M. G.; Kvansakul, M.

10.1101/2020.01.21.914671 — microbiology — Posted on 2020-01-23

1293 Breastmilk-promoted bifidobacteria produce aromatic lactic acids in the infant gut

Laursen, M. F.; Sakanaka, M.; von Burg, N.; Andersen, D.; Mörbe, U.; Rivollier, A.; Pekmez, C. T.; Moll, J. M.; Michaelsen, K. F.; Molgaard, C.; Lind, M. V.; Dragsted, L. O.; Katayama, T.; Frandsen, H. L.; Vinggaard, A. M.; Bahl, M. I.; Brix, S.; Agace, W.; Licht, T. R.; Roager, H. M.

10.1101/2020.01.22.914994 — microbiology — Posted on 2020-01-23

1294 Medical data and machine learning improve power of stroke genome-wide association studies.

Thangaraj, P. M.; Tatonetti, N.

10.1101/2020.01.22.915397 — genomics — Posted on 2020-01-23

1295 Candida albicans exhibits distinct cytoprotective responses to anti-fungal drugs that facilitate the evolution of drug resistance

Bettauer, V.; Massahi, S.; Khurdia, S.; Costa, A.; Omran, R.; Khosravi, N.; Simpson, S.; Harb, M.; Dumeaux, V.; Whiteway, M.; Hallett, M.

10.1101/2020.01.21.914549 — genomics — Posted on 2020-01-23

1296 Pyphe: A python toolbox for assessing microbial growth and cell viability in high-throughput colony screens

Kamrad, S.; Rodriguez-Lopez, M.; Cotobal, C.; Correia-Melo, C.; Ralser, M.; Bahler, J.

10.1101/2020.01.22.915363 — genomics — Posted on 2020-01-23

1297 Recipient and donor characteristics govern the hierarchical structure of heterospecific pollen competition networks

B. Lanuza, J.; Bartomeus, I.; Ashman, T.-L.; Rader, R.

10.1101/2020.01.21.914515 — ecology — Posted on 2020-01-23

1298 Moderate episodic prenatal alcohol does not impact female offspring fertility in rats

McReight, E.; Liew, S.; Steane, S.; Hutt, K.; Moritz, K.; Akison, L.

10.1101/2020.01.21.914648 — developmental biology — Posted on 2020-01-23

1299 Linker histone H1 determines cell stiffness and differentiation

Kijima, M.; Yamagish, H.; Kawano, R.; Konishi, T.; Okumura, T.; Hayase, M.; Mizuta, R.

10.1101/2020.01.21.914770 — cell biology — Posted on 2020-01-23

1300 Isolation and long-term expansion of a single adult human renal epithelial cell with efficient kidney regeneration capacity

Wang, Y.; Zhao, Z.; Ma, Q.; Nie, H.; Sun, Y.; Feng, X.; Zhang, T.; Ma, Y.; Nie, J.; Zuo, W.

10.1101/2020.01.21.914762 — cell biology — Posted on 2020-01-23

1301 Intrinsic fluorescence in non-aromatic peptide structures is induced by collective vibrations, charge reorganisation and short hydrogen bonds, as shown in a new glutamine-related structure

Stephens, A. D.; Qaisrani, M. N.; Ruggiero, M. T.; Jones, S. T. E.; Poli, E.; Bond, A. D.; Woodhams, P. J.; Kleist, E. M.; Grisanti, L.; Gebauer, R.; Zeitler, J. A.; Credgington, D.; Hassanali, A.; Kaminski Schierle, G. S.

10.1101/2020.01.22.915306 — biophysics — Posted on 2020-01-23

1302 Fivepseq: analysis of 5' count distribution in RNA-seq datasets for inference on mRNA degradation and translation

Nersisyan, L.; Ropat, M.; Pelechano, V.

10.1101/2020.01.22.915421 — genomics — Posted on 2020-01-23

1303 Using encounter data to improve capture-recapture abundance estimates

Joseph, M. B.; Knapp, R. A.

10.1101/2020.01.22.915314 — ecology — Posted on 2020-01-23

1304 Independent evolution of transcript abundance and gene regulatory dynamics

Krieger, G.; Lupo, O.; Levy, A. A.; Barkai, N.

10.1101/2020.01.22.915033 — systems biology — Posted on 2020-01-23

1305 Establishing Probiotic Saccharomyces boulardii as a Model Organism for Synthesis and Delivery of Biomolecules

Durmusoglu, D.; Al'Abri, I. S.; Collins, S. P.; Beisel, C.; Crook, N. C.

10.1101/2020.01.22.915389 — synthetic biology — Posted on 2020-01-23

1306 Are Maize Stalks Efficiently Tapered to Withstand Wind Induced Bending Stresses?

Stubbs, C. J.; Seegmiller, K.; Sekhon, R. S.; Robertson, D. J.

10.1101/2020.01.21.914804 — biophysics — Posted on 2020-01-23

1307 A repository of web-based bioinformatics resources developed in India

Agarwal, A.; Agrawal, P.; Sharma, A.; Kumar, V.; Mugdal, C.; Raghava, G. P. S.

10.1101/2020.01.21.855627 — bioinformatics — Posted on 2020-01-23

1308 Nipponbare and wild rice species as unexpected tolerance and susceptibility sources against Schizotetranychus oryzae (Acari: Tetranychidae) mite infestation

Buffon, G.; Blasi, E. A. d. R.; Lamb, T. I.; Adamski, J. M.; Schwambach, J.; Ricachenevsky, F. K.; Bertolazi, A.; Silveira, V.; Lopes, M. C. B.; Sperotto, R. A.

10.1101/2020.01.22.914184 — plant biology — Posted on 2020-01-23

1309 Arabidopsis ERF4 and MYB52 Transcription Factors Play Antagonistic Roles in Regulating Homogalacturonan De-methylesterification in Seed Coat Mucilage

Ding, A.; Tang, X.; Han, L.; Sun, J.; Ren, A.; Sun, J.; Xu, Z.; Hu, R.; Zhou, G.; Kong, Y.

10.1101/2020.01.21.914390 — plant biology — Posted on 2020-01-23

1310 ARF1 dimerization is essential for vesicle trafficking and dependent on activation by ARF-GEF dimers in Arabidopsis

Brumm, S.; Nielsen, M. E.; Richter, S.; Beckmann, H.; Stierhof, Y.-D.; Singh, M. K.; Fischer, A.-M.; Sundaresan, V.; Juergens, G.

10.1101/2020.01.21.913905 — plant biology — Posted on 2020-01-23

1311 Fluorescence Labeling of Circulating Tumor Cells with Folate Receptor Targeted Molecular Probes for Diffuse In Vivo Flow Cytometry

Patil, R. A.; Srinivasarao, M.; Amiji, M.; Low, P. S.; Niedre, M.

10.1101/2020.01.22.913137 — bioengineering — Posted on 2020-01-23

1312 Hesperetin inhibits foam cell formation in macrophages via activating LXRα signal in an AMPK dependent manner

Chen, X.; Zou, D.; Chen, X.; Wu, H.; Xu, D.

10.1101/2020.01.22.915819 — pharmacology and toxicology — Posted on 2020-01-23

1313 Exploiting toxin internalization receptors to enhance delivery of proteins to lysosomes for enzyme replacement therapy

Sugiman-Marangos, S.; Beilhartz, G. L.; Zhao, X.; Zhou, D.; Hua, R.; Kim, P. K.; Rini, J. M.; Minassian, B. A.; Melnyk, R. A.

10.1101/2020.01.22.915298 — pharmacology and toxicology — Posted on 2020-01-23

1314 Disentangling the roles of neocortical alpha/beta and hippocampal theta/gamma activity in human episodic memory

Griffiths, B. J.; Martin-Buro, M. C.; Staresina, B.; Hanslmayr, S.

10.1101/2020.01.22.915330 — neuroscience — Posted on 2020-01-23

1315 Remodeling of pre-existing myelinated axons and oligodendrocytes is stimulated by environmental enrichment in the young adult brain

Nicholson, M.; Wood, R. J.; Fletcher, J.; Gonsalvez, D. G.; Hannan, A. J.; Murray, S. S.; Xiao, J.

10.1101/2020.01.21.914572 — neuroscience — Posted on 2020-01-23

1316 Self-generated whisker movements drive state-dependent sensory input to developing barrel cortex

Dooley, J. C.; Glanz, R. M.; Sokoloff, G.; Blumberg, M. S.

10.1101/2020.01.21.914259 — neuroscience — Posted on 2020-01-23

1317 The Sapap3-knockout mouse model manifests a spectrum of repetitive behaviours

Lamothe, H.; Schreiweis, C.; Mallet, L.; Burguiere, E.

10.1101/2020.01.22.915215 — neuroscience — Posted on 2020-01-23

1318 Capsaicin and its analogues impede nocifensive response of Caenorhabditis elegans to noxious heat

Nkambeu, B.; Ben Salem, J.; Beaudry, F.

10.1101/2020.01.21.914010 — neuroscience — Posted on 2020-01-23

1319 Neural differentiation is moderated by age in scene- but not face-selective cortical regions

Srokova, S.; Hill, P. F.; Koen, J. D.; King, D. R.; Rugg, M. D.

10.1101/2020.01.21.914432 — neuroscience — Posted on 2020-01-23

1320 Early postnatal inhibitory circuit development in the mouse medial prefrontal and primary somatosensory cortex

Kalemaki, K.; Xu, X.; Hanganu-Opatz, I. L.; Sidiropoulou, K.; Karagogeos, D.

10.1101/2020.01.21.913913 — neuroscience — Posted on 2020-01-23

1321 Tagsteady: a metabarcoding library preparation protocol to avoid false assignment of sequences to samples

Caroe, C.; Bohmann, K.

10.1101/2020.01.22.915009 — molecular biology — Posted on 2020-01-23

1322 Structures of three actinobacteriophage capsids: Roles of symmetry and accessory proteins

Podgorski, J.; Calabrese, J.; Alexandrescu, L.; Jacobs-Sera, D.; Pope, W.; Hatfull, G.; White, S.

10.1101/2020.01.21.914465 — microbiology — Posted on 2020-01-23

1323 First description of a herpesvirus infection in genus Lepus

Abade dos Santos, F. A.; Monteiro, M.; Pinto, A.; Carvalho, C. L.; Peleteiro, M. C.; Carvalho, P.; Mendonca, P.; Carvalho, T.; Duarte, M. D.

10.1101/2020.01.21.913723 — microbiology — Posted on 2020-01-23

1324 Alteration of fecal microbial compositions and bacterial taxa in female osteoporotic patients

Zhu, C.; Xu, A.; Wang, K.; Pan, Y.; Liu, J.; Pan, Y.; Fan, Y.; Jin, L.; Liu, Y.; Zhang, Z.; Gan, Y.; Tang, W.; Li, J.; Xionga, Z.; Xu, G.; Lin, X.; Zhang, Y.; Cai, J.; Yang, M.; Zhang, L.; Xiao, L.

10.1101/2020.01.21.914903 — microbiology — Posted on 2020-01-23

1325 Mechanism of Action of a Prostaglandin E2 Receptor Antagonist with antimicrobial activity against Staphylococcus aureus

Lilly, E. A.; Ikeh, M. A. C.; Fidel, P. L.; Noverr, M. C.

10.1101/2020.01.21.914200 — microbiology — Posted on 2020-01-23

1326 A bacterial symbiont protects honey bees from fungal disease

Milller, D. L.; Smith, E. A.; Newton, I.

10.1101/2020.01.21.914325 — microbiology — Posted on 2020-01-23

1327 Bcl6 Preserves the Suppressive Function of Regulatory T Cells during Tumorigenesis

Li, Y.; Wang, Z.; Lin, H.; Wang, L.; Chen, X.; Liu, Q.; Zuo, Q.; Hu, J.; Wang, H.; Guo, J.; Xie, L.; Tang, J.; Li, Z.; Hu, L.; Ye, L.; Huang, Q.; Xu, L.

10.1101/2020.01.21.914812 — immunology — Posted on 2020-01-23

1328 Construction of Nanobody Library in Mammalian Cells by Linear-double-stranded DNA Based AND Gate Genetic Circuit

Zhang, C.; Tong, X.; Li, S.

10.1101/2020.01.21.912907 — immunology — Posted on 2020-01-23

1329 Human immune system variation during one year

Lakshmikanth, T.; Muhammad, S. A.; Olin, A.; Chen, Y.; Mikes, J.; Fagerberg, L.; Gummesson, A.; Bergstrom, G.; Uhlen, M.; Brodin, P.

10.1101/2020.01.22.915025 — immunology — Posted on 2020-01-23

1330 Genome-wide scale analyses identify novel BMI genotype-environment interactions using a conditional false discovery rate

Moore, R.; Georgatou-Politou, L.; Liley, J.; Stegle, O.; Barroso, I.

10.1101/2020.01.22.908038 — genetics — Posted on 2020-01-23

1331 Investigating the causal effect of maternal vitamin B12 and folate levels on offspring birthweight

Moen, G.-H.; Beaumont, R. N.; Sommer, C.; Shields, B. M.; Lawlor, D. A.; Freathy, R. M.; Evans, D. M.; Warrington, N. M.

10.1101/2020.01.21.914655 — genetics — Posted on 2020-01-23

1332 m6A Regulates Liver Metabolic Disorders and Hepatogenous Diabetes

li, Y.; Zhang, Q.; Cui, G.; Zhao, F.; Tian, X.; Sun, B.-F.; Yang, Y.; Li, W.

10.1101/2020.01.21.912600 — genetics — Posted on 2020-01-23

1333 The effect of genetic architecture and selfing on the capacity of a population to expand its range

Eriksson, M.; Rafajlovic, M.

10.1101/2020.01.22.915454 — evolutionary biology — Posted on 2020-01-23

1334 Evidence of Absence Regression: A Binomial N-Mixture Model for Estimating Bird and Bat Fatalities at Wind Power Facilities

McDonald, T.; Bay, K.; Studyvin, J.; Leckband, J.; Schorg, A.; McIvor, J.

10.1101/2020.01.21.914754 — ecology — Posted on 2020-01-23

1335 Synchrony and perturbation transmission in trophic metacommunities

Quevreux, P.; Barbier, M.; Loreau, M.

10.1101/2020.01.21.914093 — ecology — Posted on 2020-01-23

1336 Behavioural traits and feeding ecology of Mediterranean lionfish and native species naivete to lionfish predation

D'Agostino, D.; Jimenez, C.; Reader, T.; Hadjioannou, L.; Heyworth, S.; Aplikioti, M.; Argyrou, M.; Feary, D. A.

10.1101/2020.01.22.915322 — ecology — Posted on 2020-01-23

1337 Poor hive thermoregulation produces an Allee effect and leads to colony collapse

Zeaiter, Z.; Myerscough, M. R.

10.1101/2020.01.21.914697 — ecology — Posted on 2020-01-23

1338 Taking a landscape approach to conservation goals: designing multi-objective landscapes

Renwick, A. R.; Chauvenet, A. L. M.; Possingham, H. P.; Adams, V. M.; McGowan, J.; Gagic, V.; Schellhorn, N. A.

10.1101/2020.01.21.914721 — ecology — Posted on 2020-01-23

1339 Megafauna decline have reduced pathogen dispersal which may have increased emergent infectious diseases

Doughty, C.; Prys-Jones, T.; Faurby, S.; Abraham, A.; Hepp, C.; Fofanov, V.; Leshyk, V.; Svenning, J.-C.; Galetti, M.

10.1101/2020.01.21.914531 — ecology — Posted on 2020-01-23

1340 Cancer-associated HIF-2α impacts trunk neural crest stemness

Mohlin, S.; Persson, C. U.; Fredlund, E.; Monni, E.; Lindvall, J. M.; Kokaia, Z.; Hammarlund, E.; Bronner, M. E.

10.1101/2020.01.22.915199 — developmental biology — Posted on 2020-01-23

1341 Single platelet variability governs population sensitivity and initiates intrinsic heterotypic behaviours

Jongen, M. S. A.; MacArthur, B.; Englyst, N. A.; West, J.

10.1101/2020.01.22.915512 — cell biology — Posted on 2020-01-23

1342 Lineage reversion drives WNT independence in intestinal cancer

Han, T.; Goswami, S.; Hu, Y.; Tang, F.; Zafra, M. P.; Murphy, C.; Cao, Z.; Poirier, J. T.; Khurana, E.; Elemento, O.; Hechtman, J. F.; Yeager, R.; Dow, L. E.

10.1101/2020.01.22.914689 — cancer biology — Posted on 2020-01-23

1343 Epithelial organ shape is generated by patterned actomyosin contractility and maintained by the extracellular matrix

Nematbakhsh, A.; Levis, M.; Kumar, N.; Chen, W.; Zartman, J. J.; Alber, M.

10.1101/2020.01.22.915272 — biophysics — Posted on 2020-01-23

1344 Automated Isoform Diversity Detector (AIDD): A pipeline for investigating transcriptome diversity of RNA-seq data

Plonski, N.-M.; Johnson, E.; Frederick, M.; Mercer, H.; Fraizer, G.; Meindl, R.; Casadesus, G.; Piontkivska, H.

10.1101/2020.01.22.915348 — bioinformatics — Posted on 2020-01-23

1345 BlastFrost: Fast querying of 100,000s of bacterial genomes in Bifrost graphs

Luhmann, N.; Holley, G.; Achtman, M.

10.1101/2020.01.21.914168 — bioinformatics — Posted on 2020-01-23

1346 EEG-informed speaker extraction from noisy recordings in neuro-steered hearing aids: linear versus deep learning methods

Das, N.; Zegers, J.; Van hamme, H.; Francart, T.; Bertrand, A.

10.1101/2020.01.22.915181 — bioengineering — Posted on 2020-01-23

1347 High sensitivity (zeptomole) detection of BODIPY heparan sulfate (HS) disaccharides by ion-paired RP-HPLC and LIF detection enables analysis of HS from mosquito midguts.

Maciej-Hulme, M. L.; Leprince, A. C.; Lavin, A.; Guimond, S. E.; Turnbull, J. E.; Pelletier, J.; Yates, E. A.; Powell, A. K.; Skidmore, M. A.

10.1101/2020.01.21.913954 — biochemistry — Posted on 2020-01-23

1348 CryoEM structures of human CMG - ATPγS - DNA and CMG - AND-1 complexes

Rzechorzek, N. J.; Hardwick, S. W.; Jatikusumo, V. A.; Chirgadze, D. Y.; Pellegrini, L.

10.1101/2020.01.22.914192 — biochemistry — Posted on 2020-01-23

1349 Biomechanical Regulation of Breast Cancer Metastasis and Progression

Spencer, A.; Sligar, A.; Chavarria, D.; Lee, J.; Choksi, D.; Patil, N.; Lee, H.; Veith, A.; Riley, W.; Desai, S.; Abbaspour, A.; Singeetham, R.; Baker, A.

10.1101/2020.01.21.914242 — cancer biology — Posted on 2020-01-23

1350 AStarix: Fast and Optimal Sequence-to-Graph Alignment

Ivanov, P.; Bichsel, B.; Mustafa, H.; Kahles, A.; Rätsch, G.; Vechev, M.

10.1101/2020.01.22.915496 — bioinformatics — Posted on 2020-01-23

1351 The combination of lipopolysaccharide and D-galactosamine administration show positive genotoxic effect in mice liver

Song, Y.; DONG, W.; SONG, E.

10.1101/2020.01.22.915108 — cell biology — Posted on 2020-01-22

1352 Arachidonic acid promotes the binding of 5-lipoxygenase on nanodiscs containing 5-lipoxygenase activating protein in the absence of calcium-ions.

Kumar, R. B.; Purhonen, P.; Hebert, H.; Jegerschöld, C.

10.1101/2020.01.22.915090 — biochemistry — Posted on 2020-01-22

1353 Large-scale metabarcoding analysis of epipelagic and mesopelagic copepods in the Pacific

Hirai, J.; Tachibana, A.; Tsuda, A.

10.1101/2020.01.22.915082 — ecology — Posted on 2020-01-22

1354 Environmental heterogeneity ruling the action of ecological processes over the bacterial metacommunity assembly

Huber, P.; Metz, S.; Unrein, F.; Mayora, G.; Sarmento, H.; Devercelli, M.

10.1101/2020.01.21.914234 — ecology — Posted on 2020-01-22

1355 Wolbachia affect behavior and possibly reproductive compatibility but not thermoresistance, fecundity, and morphology in a novel transinfected host, Drosophila nigrosparsa

Detcharoen, M.; Arthofer, W.; Jiggins, F. M.; Steiner, F. M.; Schlick-Steiner, B. C.

10.1101/2020.01.21.913848 — ecology — Posted on 2020-01-22

1356 The role of maternal effects on offspring performance in familiar and novel environments

Vrtilek, M.; Chuard, P. J. C.; Iglesias-Carrasco, M.; Jennions, M. D.; Head, M. L.

10.1101/2020.01.21.913822 — evolutionary biology — Posted on 2020-01-22

1357 Super elongation complex as a targetable dependency in diffuse midline glioma

Dahl, N. A.; Danis, E.; Balakrishnan, I.; Wang, D.; Pierce, A.; Walker, F.; Gilani, A.; Serkova, N.; Madhaven, K.; Fosmire, S.; Green, A.; Foreman, N. K.; Venkataraman, S.; Vibhakar, R.

10.1101/2020.01.22.913244 — cancer biology — Posted on 2020-01-22

1358 Visualization and normalization of drift effect across batches in metabolome-wide association studies

Bararpour, N.; Gilardi, F.; Carmeli, C.; Sidibe, J.; Ivanisevic, J.; Caputo, T.; Augsburger, M.; Grabherr, S.; Desvergne, B.; Guex, N.; Bochud, M.; Thomas, A.

10.1101/2020.01.22.914051 — bioinformatics — Posted on 2020-01-22

1359 Phosphatidylinositol-4-kinase IIα licenses phagosomes for TLR4 signaling and MHC-II presentation in dendritic cells

Lopez-Haber, C.; Levin-Konigsberg, R.; Zhu, Y.; Bi-Karchin, J.; Balla, T.; Grinstein, S.; Marks, M. S.; Mantegazza, A. R.

10.1101/2020.01.22.915017 — cell biology — Posted on 2020-01-22

1360 Lipid accumulation promotes scission of caveolae

Hubert, M.; Larsson, E.; Vegesna, N. V. G.; Ahnlund, M.; Johansson, A. I.; Moodie, L. W. K.; Lundmark, R.

10.1101/2020.01.22.915173 — biochemistry — Posted on 2020-01-22

1361 Quantitative microbiome profiling in lumenal and tissue samples with broad coverage and dynamic range via a single-step 16S rRNA gene DNA copy quantification and amplicon barcoding

Bogatyrev, S. R.; Ismagilov, R. F.

10.1101/2020.01.22.914705 — bioengineering — Posted on 2020-01-22

1362 Vps13D is required for mitochondrial fission and mitophagy triggered by fission defects in Drosophila neurons

Insolera, R.; Lorincz, P.; Wishnie, A. J.; Juhasz, G.; Collins, C. A.

10.1101/2020.01.21.914523 — cell biology — Posted on 2020-01-22

1363 Identification of PIM1 substrates reveals a role for NDRG1 in prostate cancer cellular migration and invasion

Ledet, R. J.; Ruff, S.; Wang, Y.; Nayak, S.; Schneider, J. A.; Ueberheide, B.; Logan, S. K.; Garabedian, M. J.

10.1101/2020.01.21.913962 — cancer biology — Posted on 2020-01-22

1364 Use of high-refractive index hydrogels and tissue clearing for large biological sample imaging

Richardson, A.; Fok, S.; Lee, V.; Rye, K.-A.; Di Girolamo, N.; Cochran, B. J.

10.1101/2020.01.22.905695 — pathology — Posted on 2020-01-22

1365 Prenylation of axonally translated proteins controls NGF-dependent axon growth

Scott-Solomon, E.; Kuruvilla, R.

10.1101/2020.01.21.914606 — neuroscience — Posted on 2020-01-22

1366 Functional assessment of cell entry and receptor usage for lineage B β-coronaviruses, including 2019-nCoV

Letko, M. C.; Munster, V.

10.1101/2020.01.22.915660 — microbiology — Posted on 2020-01-22

1367 Post-prediction inference

Wang, S.; McCormick, T. H.; Leek, J. T.

10.1101/2020.01.21.914002 — bioinformatics — Posted on 2020-01-22

1368 Reinforcement learning as an intermediate phenotype in psychosis? Deficits sensitive to illness stage but not associated with polygenic risk of schizophrenia in the general population

Montagnese, M.; Knolle, F.; Haarsma, J.; Griffin, J.; Richards, A.; Vertes, P.; Kiddle, B.; Fletcher, P.; Jones, P.; Owen, M.; Fonagy, P.; Bullmore, E.; Dolan, R.; NSPN Consortium, ; Moutoussis, M.; Goodyer, I.; Murray, G. K.

10.1101/668939 — neuroscience — Posted on 2020-01-22

1369 Cold-induced switch in direction of chloroplast relocation occurs independently of changes in endogenous phototropin expression

Fujii, Y.; Ogasawara, Y.; Takahashi, Y.; Sakata, M.; Tamura, S.; Kodama, Y.

10.1101/544361 — plant biology — Posted on 2020-01-22

1370 Identification of two new trichome-specific promoters of Nicotiana tabacum

Pottier, M.; Laterre, R.; Van Wessem, A.; M. Ramirez, A.; Herman, X.; Boutry, M.; Hachez, C.

10.1101/620021 — plant biology — Posted on 2020-01-22

1371 A Domain-general Cognitive Core defined in Multimodally Parcellated Human Cortex

Assem, M.; Glasser, M. F.; Van Essen, D. C.; Duncan, J.

10.1101/517599 — neuroscience — Posted on 2020-01-22

1372 Stereomotion processing in the non-human primate brain

Hejja-Brichard, Y.; Rima, S.; Rapha, E.; Durand, J.-B.; Cottereau, B. R.

10.1101/638155 — neuroscience — Posted on 2020-01-22

1373 The Cu(II) reductase RclA protects Escherichia coli against the combination of hypochlorous acid and intracellular copper

Derke, R. M.; Barron, A. J.; Billiot, C. E.; Chaple, I. F.; Lapi, S. E.; Broderick, N. A.; Gray, M. J.

10.1101/690669 — microbiology — Posted on 2020-01-22

1374 Deciphering Functional Redundancy in the Human Microbiome

Tian, L.; Wang, X.-W.; Wu, A.-K.; Fan, Y.; Friedman, J.; Dahlin, A.; Waldor, M. K.; Weinstock, G.; Weiss, S. T.; Liu, Y.-Y.

10.1101/176313 — microbiology — Posted on 2020-01-22

1375 Aging immune system-related blood cell DNA methylation can predict the onset of early stage colorectal cancer

Quan, Y.; Liang, F.; Wu, D.; Yao, X.; Zhu, Y.; Chen, Y.; Wu, A.; Tang, D.; Huang, B.; Xu, R.; Lyu, Z.; Yan, Q.; Ning, Z.; Li, Y.; Xiong, J.

10.1101/2020.01.13.905299 — cancer biology — Posted on 2020-01-22

1376 Prediction of drug-target binding affinity using graph neural networks

Nguyen, T.; Le, H.; Quinn, T. P.; Le, T.; Venkatesh, S.

10.1101/684662 — bioinformatics — Posted on 2020-01-22

1377 Nwd1 regulates neuronal differentiation and migration through purinosome formation in the developing cerebral cortex

Yamada, S.; Sato, A.; Sakakibara, S.-i.

10.1101/2019.12.15.877340 — neuroscience — Posted on 2020-01-22

1378 Cross-Cancer Evaluation of Polygenic Risk Scores for 17 Cancer Types in Two Large Cohorts

Graff, R. E.; Cavazos, T. B.; Thai, K. K.; Kachuri, L.; Rashkin, S. R.; Hoffman, J. D.; Alexeeff, S. E.; Blatchins, M.; Meyers, T. J.; Leong, L.; Tai, C. G.; Emami, N. C.; Corley, D. A.; Kushi, L. H.; Ziv, E.; Van Den Eeden, S. K.; Jorgenson, E.; Hoffmann, T. J.; Habel, L. A.; Witte, J. S.; Sakoda, L. C.

10.1101/2020.01.18.911578 — genetics — Posted on 2020-01-22

1379 Clustered γ-Protocadherins Regulate Cortical Interneuron Programmed Cell Death.

Mancia Leon, W. R.; Spatazza, J.; Rakela, B.; Chatterjee, A.; Pande, V.; Maniatis, T.; Hasenstaub, A. R.; Stryker, M. P.; Alvarez-Buylla, A.

10.1101/2020.01.14.906941 — neuroscience — Posted on 2020-01-22

1380 Lipopolysaccharide Simulations are Sensitive to Phosphate Charge and Ion Parameterization

Rice, A.; Rooney, M. T.; Greenwood, A. I.; Cotten, M.; Weresczczynski, J.

10.1101/752188 — biophysics — Posted on 2020-01-22

1381 Single-cell ChIP-seq imputation with SIMPA by leveraging bulk ENCODE data

Albrecht, S.; Andreani, T.; Andrade-Navarro, M. A.; Fontaine, J.-F.

10.1101/2019.12.20.883983 — bioinformatics — Posted on 2020-01-22

1382 Exploring neighborhoods in large metagenome assembly graphs reveals hidden sequence diversity

Brown, C. T.; Moritz, D.; O'Brien, M.; Reidl, F.; Reiter, T.; Sullivan, B.

10.1101/462788 — bioinformatics — Posted on 2020-01-22

1383 Mechanical competition triggered by innate immune signaling drives the collective extrusion of bacterially-infected epithelial cells

Bastounis, E. E.; Alcade, F. S.; Radhakrishnan, P.; Engstrom, P.; Gomez Benito, M. J.; Welch, M.; Garcia-Aznar, J. M.; Theriot, J. A.

10.1101/2020.01.22.915140 — microbiology — Posted on 2020-01-22

1384 Single-cell metabolic analysis by mass cytometry reveals distinct transitional states of CD8 T cell differentiation

Levine, L. S.; Hiam, K. J.; Marquez, D. M.; Tenvooren, I.; Contreras, D. C.; Rathmell, J. C.; Spitzer, M. H.

10.1101/2020.01.21.911545 — immunology — Posted on 2020-01-22

1385 A defect in thymic tolerance causes T cell-mediated autoimmunity in a murine model of COPA syndrome

Deng, Z.; Law, C. S.; Ho, F. O.; Wang, K. M.; Jones, K. D.; Shin, J.-S.; Shum, A.

10.1101/2020.01.21.914440 — immunology — Posted on 2020-01-22

1386 RdDM pathway is required for Tobamovirus-induced symptomatology production

Leone, M.; Zavallo, D.; Venturuzzi, A. L.; Asurmendi, S.

10.1101/2020.01.21.912923 — plant biology — Posted on 2020-01-22

1387 An Anti-amyloidogenic treatment to specifically block the consolidation of traumatic events in mouse

Lopez-Garcia, P.; Ramirez de Mingo, D.; McGreevy, K. R.; Palle Lopez, A.; Popiel, H. A.; Santi, A.; Nagai, Y.; Trejo, J. L.; Carrion-Vazquez, M.

10.1101/2020.01.21.913053 — animal behavior and cognition — Posted on 2020-01-22

1388 Bagging Improves Reproducibility of Functional Parcellation of the Human Brain

Nikolaidis, A.; Solon Heinsfeld, A.; Xu, T.; Bellec, P.; Vogelstein, J.; Milham, M.

10.1101/343392 — neuroscience — Posted on 2020-01-22

1389 Dynamic evolution of great ape Y chromosomes

Cechova, M.; Vegesna, R.; Tomaszkiewicz, M.; Harris, R. S.; Chen, D.; Rangavittal, S.; Medvedev, P.; Makova, K.

10.1101/2020.01.21.913863 — evolutionary biology — Posted on 2020-01-22

1390 A Drosophila model of oral peptide therapeutics for adult intestinal stem cell tumors

Bajpai, A.; Ahmad, Q. T.; Hong-Wen Tang, H.-W.; Manzar, N.; Singh, V.; Thakur, A.; Ateeq, B.; Perrimon, N.; Sinha, P.

10.1101/2020.01.21.913806 — cancer biology — Posted on 2020-01-22

1391 The photoreceptor UVR8 mediates the perception of both UV-B and UV-A wavelengths up to 350 nm of sunlight with responsivity moderated by cryptochromes

Rai, N.; O'Hara, A.; Farkas, D.; Safronov, O.; Ratanasopa, K.; Wang, F.; Lindfors, A.; Jenkins, G.; Lehto, T.; Salojarvi, J.; Brosche, M.; Strid, A.; Aphalo, P.; Morales Suarez, L. O.

10.1101/2020.01.21.913814 — plant biology — Posted on 2020-01-22

1392 Transcriptomic homogeneity and an age-dependent onset of hemoglobin expression characterize morphological PV types

Que, L.; Lukacsovich, D.; Foldy, C.

10.1101/2020.01.21.913103 — neuroscience — Posted on 2020-01-22

1393 Meta-analysis of 139 extant Tara ocean metagenomes to unveil the relationship between taxonomy and functionality in prokaryotes inhabiting aquatic ecosystems

Starke, R.

10.1101/2020.01.21.913830 — microbiology — Posted on 2020-01-22

1394 Increased nitrogen fixation and remobilization may contribute to higher seed protein without a yield penalty in a soybean introgression line

Locke, A. M.; Ramirez, M. E.

10.1101/602748 — plant biology — Posted on 2020-01-22

1395 Mitochondria-adaptor TRAK1 promotes kinesin-1 driven transport in crowded environments

Henrichs, V.; Grycova, L.; Barinka, C.; Nahacka, Z.; Neuzil, J.; Diez, S.; Rohlena, J.; Braun, M.; Lansky, Z.

10.1101/2020.01.22.915066 — cell biology — Posted on 2020-01-22

1396 Genomic and protein structure modelling analysis depicts the origin and infectivity of 2019-nCoV, a new coronavirus which caused a pneumonia outbreak in Wuhan, China

Dong, N.; Yang, X.; Chen, K.; Chan, E.; Yang, M.; Chen, S.

10.1101/2020.01.20.913368 — microbiology — Posted on 2020-01-22

1397 Crystal structure of a human plasma membrane phospholipid flippase

Nakanishi, H.; Irie, K.; Segawa, K.; Hasegawa, K.; Fujiyoshi, Y.; Nagata, S.; Abe, K.

10.1101/2019.12.23.881698 — biochemistry — Posted on 2020-01-22

1398 The Linker Domain of SNAP25 Acts as a Flexible Molecular Spacer to Ensure Efficient S-Acylation

Salaun, C.; Greaves, J.; Tomkinson, N. C. O.; Chamberlain, L. H.

10.1101/2020.01.21.914333 — cell biology — Posted on 2020-01-22

1399 A Connectome of the Adult Drosophila Central Brain

Xu, C. S.; Januszewski, M.; Lu, Z.; Takemura, S.-y.; Hayworth, K.; Huang, G.; Shinomiya, K.; Maitin-Shepard, J.; Ackerman, D.; Berg, S.; Blakely, T.; Bogovic, J.; Clements, J.; Dolafi, T.; Hubbard, P.; Kainmueller, D.; Katz, W.; Kawase, T.; Khairy, K.; Leavitt, L.; Li, P. H.; Lindsey, L.; Neubarth, N.; Olbris, D. J.; Otsuna, H.; Troutman, E. T.; Umayam, L.; Zhao, T.; Ito, M.; Goldammer, J.; Wolff, T.; Svirskas, R.; Schlegel, P.; Neace, E. R.; Knecht, C. J.; Alvarado, C. X.; Bailey, D.; Ballinger, S.; Borycz, J. A.; Canino, B.; Cheatham, N.; Cook, M.; Dreyer, M.; Duclos, O.; Eubanks, B.; Fairba

10.1101/2020.01.21.911859 — neuroscience — Posted on 2020-01-21

1400 Risk Factors for Chikungunya Outbreak in Kebridhar City, Somali Ethiopia, 2019. Unmatched Case-Control Study

Alayu, M.; Teshome, T.; Amare, H.; Kinde, S.; Belay, D.; Assefa, Z.

10.1101/2020.01.21.913673 — scientific communication and education — Posted on 2020-01-21

1401 Toxic effect of 2,2'-bis(bicyclo heptane) on bacterial cells.

Kessenikh, A. G.; Gnuchikh, E. Y.; Bazhenov, S. V.; Bermeshev, M. V.; Pevgov, V. G.; Shorunov, S. V.; Samoilov, V. O.; Maksimov, A. L.; Yaguzhinsky, L. S.; Manukhov, I.

10.1101/2020.01.21.913699 — pharmacology and toxicology — Posted on 2020-01-21

1402 Can early exposure to stress enhance resilience to ocean warming in two oyster species?

Pereira, R.; Scanes, E.; Gibbs, M.; Byrne, M.; Ross, P.

10.1101/2020.01.21.913715 — ecology — Posted on 2020-01-21

1403 Desmosomes pattern cell mechanics to govern epidermal tissue form and function

Broussard, J. A.; Koetsier, J. L.; Green, K. J.

10.1101/2020.01.21.914176 — cell biology — Posted on 2020-01-21

1404 Membrane-mediated ligand unbinding of the PK-11195 ligand from the translocator protein (TSPO)

Dixon, T.; Uyar, A.; Ferguson-Miller, S.; Dickson, A.

10.1101/2020.01.21.914127 — biophysics — Posted on 2020-01-21

1405 High-resolution cryo-EM using beam-image shift at 200 keV

Cash, J. N.; Kearns, S.; Li, Y. A.; Cianfrocco, M. A.

10.1101/2020.01.21.914507 — biophysics — Posted on 2020-01-21

1406 Absence of Sac2/INPP5F enhances the phenotype of a Parkinson's disease mutation of synaptojanin 1

Cao, M.; Park, D.; Wu, Y.; De Camilli, P.

10.1101/2020.01.21.914317 — neuroscience — Posted on 2020-01-21

1407 Mitigating ecosystem impacts of bottom trawl fisheries for North Sea sole Solea solea by replacing mechanical by electrical stimulation

Rijnsdorp, A.; Depestele, J.; Eigaard, O. R.; Ivanovic, A.; O'Neill, F.; Polet, H.; Poos, J. J.; Kooten, T. v.

10.1101/2020.01.21.913731 — ecology — Posted on 2020-01-21

1408 Human iPS Cells Derived Skeletal Muscle Progenitor Cells Promote Myoangiogenesis and Restore Dystrophin in Duchenne Muscular Dystrophic Mice

xuan, w.; Khan, M.; Ashraf, M.

10.1101/2020.01.21.914283 — cell biology — Posted on 2020-01-21

1409 Role of RBC membrane protein palmitoylation in regulation of molecular topology and susceptibility to Plasmodium falciparum invasion

Pati, S.; Yadav, P.; Kumari, G.; D.A.B, R.; Goswami, S.; Garg, S.; Prasad, T. S. K.; Ramalingam, S.; singh, s.

10.1101/2020.01.21.913855 — cell biology — Posted on 2020-01-21

1410 What causes different coronal curve patterns in idiopathic scoliosis?

Pasha, S.

10.1101/2020.01.21.913707 — bioengineering — Posted on 2020-01-21

1411 Use of unmanned aerial vehicles (UAVs) for mark-resight nesting population estimation of adult female green sea turtles at Raine Island

Dunstan, A. J.; Robertson, K.; Fitzpatrick, R.; Pickford, J.

10.1101/2020.01.21.913681 — ecology — Posted on 2020-01-21

1412 A stable core of GCPs 4, 5 and 6 promotes the assembly of γ-tubulin ring complexes

Merdes, A.; Haren, L.; Farache, D.; Emorine, L.

10.1101/2020.01.21.914036 — cell biology — Posted on 2020-01-21

1413 Functional anatomy of the full length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis

Stephens, B. S.; Ngo, T.; Kufareva, I.; Handel, T. M.

10.1101/2020.01.21.913772 — pharmacology and toxicology — Posted on 2020-01-21

1414 Fixed human-specific neuro-regulatory single nucleotide mutations manifest staggering breadth of associations with physiological processes, morphological features, and pathological conditions of Modern Humans

Glinsky, G.

10.1101/848762 — genomics — Posted on 2020-01-21

1415 High Force Catch Bond Mechanism of Bacterial Adhesion in the Human Gut

Liu, Z.; Liu, H.; Vera, A. M.; Bernardi, R. C.; Tinnefeld, P.; Nash, M. A.

10.1101/2020.01.21.913590 — biophysics — Posted on 2020-01-21

1416 Deep learning based behavioral analysis enables high precision rodent tracking and is capable of outperforming commercial solutions

Sturman, O.; von Ziegler, L. M.; Schälppi, C.; Akyol, F.; Grewe, B. F.; Bohacek, J.

10.1101/2020.01.21.913624 — animal behavior and cognition — Posted on 2020-01-21

1417 Honey bee queen production: Canadian costing case study and profitability analysis

Bixby, M. E. F.; Hoover, S.; McCallum, R.; Ibrahim, A.; Ovinge, L.; Olmstead, S.; Pernal, S.; Zayed, A.; Foster, L.; Guarna, M. M.

10.1101/2020.01.14.906461 — ecology — Posted on 2020-01-21

1418 Production and Purification of Endogenously Modified tRNA-Derived Small RNAs

Drino, A.; Oberbauer, V.; Troger, C.; Janisiw, E.; Anrather, D.; Hartl, M.; Kaiser, S.; Kellner, S.; Schaefer, M. R.

10.1101/2020.01.21.913749 — biochemistry — Posted on 2020-01-21

1419 Mesopredators display behaviourally plastic responses to dominant competitors when scavenging and communicating

Wang, Y.; Allen, M. L.; Wilmers, C.

10.1101/2020.01.20.913335 — ecology — Posted on 2020-01-21

1420 Detecting object boundaries in natural images requires 'incitatory' cell-cell interactions

Mel, G. C.; Ramachandra, C.; Mel, B. W.

10.1101/436949 — neuroscience — Posted on 2020-01-21

1421 Age dependent changes in synaptic NMDA receptor composition in adult human cortical neurons

Pegasiou, C. M.; Zolnourian, A.; Gomez-Nicola, D.; Deinhardt, K.; Nicoll, J.; Ahmed, A.; Vajramani, G.; Grundy, P.; Verhoog, M.; Mansvelder, H.; Perry, V. H.; Bulters, D.; Vargas-Caballero, M.

10.1101/2020.01.21.913475 — neuroscience — Posted on 2020-01-21

1422 How Sensitive are EEG Results to Preprocessing Methods: A Benchmarking Study

Robbins, K.; Touryan, J. O.; Mullen, T.; Kothe, C.; Bigdely-Shamlo, N.

10.1101/2020.01.20.913327 — neuroscience — Posted on 2020-01-21

1423 The zinc cluster transcription factor Rha1 is a positive filamentation regulator in Candida albicans

Parvizi Omran, R.; Law, C.; Dumeaux, V.; Ramirez-Zavala, B.; Morschhaeuser, J.; Whiteway, M.

10.1101/2020.01.21.901744 — microbiology — Posted on 2020-01-21

1424 Reduced function of the glutathione S-transferase S1 suppresses behavioral hyperexcitability in Drosophila expressing a mutant voltage-gated sodium channel

Chen, H.-L.; Kasuya, J.; Lansdon, P.; Kaas, G. A.; Tang, H.; Sodders, M.; Kitamoto, T.

10.1101/2020.01.21.906156 — genetics — Posted on 2020-01-21

1425 Suitable habitats of fish species in the Barents Sea

Husson, B.; Certain, G.; Filin, A.; Planque, B.

10.1101/2020.01.20.912816 — ecology — Posted on 2020-01-21

1426 The effects of seasonal climate variability on dengueannual incidence in Hong Kong: A modellingstudy

Yuan, H.-Y.; Liang, J.; Lin, P.-S.; Sucipto, K.; Tsegaye, M. M.; Wen, T.-H.; Pfeiffer, S.; Pfeiffer, D. P.

10.1101/2020.01.20.912097 — ecology — Posted on 2020-01-21

1427 A minimal 3D model of mosquito flight behavior around the human baited bed net

Jones, J.; Murray, G. D.; McCall, P. J.

10.1101/2020.01.21.913608 — animal behavior and cognition — Posted on 2020-01-21

1428 Effectiveness of protected areas in conserving tropical forest birds

Cazalis, V.; Prince, K.; Mihoub, J.-B.; Kelly, J.; Butchart, S. H. M.; Rodrigues, A. S. L.

10.1101/2020.01.21.912345 — ecology — Posted on 2020-01-21

1429 Smchd1 is a maternal effect gene required for autosomal imprinting

Wanigasuriya, I.; Gouil, Q.; Kinkel, S. A.; Tapia del Fierro, A.; Beck, T.; Roper, E. E. A.; Breslin, K.; Stringer, J.; Hutt, K.; Lee, H. J.; Keniry, A.; Ritchie, M. E.; Blewitt, M. E.

10.1101/2020.01.20.913376 — genomics — Posted on 2020-01-21

1430 Translation is required for miRNA-dependent decay of endogenous transcripts.

Biasini, A.; de Pretis, S.; Tan, J. Y.; Abdulkarim, B.; Wischnewski, H.; Dreos, R.; Pelizzola, M.; Ciaudo, C.; Marques, A. C.

10.1101/2020.01.21.913483 — genomics — Posted on 2020-01-21

1431 Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following demyelination

Saraswat, D.; Polanco, J. J.; Shayya, H. J.; Tripathi, A.; Welliver, R.; Pol, S. U.; Broome, J. E.; O'Bara, M. A.; van Kuppervelt, T. H.; Phillips, J. J.; Dutta, R.; Sim, F. J.

10.1101/2020.01.21.906073 — neuroscience — Posted on 2020-01-21

1432 Genomic and protein structure modelling analysis depicts the origin and infectivity of 2019-nCoV, a new coronavirus which caused a pneumonia outbreak in Wuhan, China

Dong, N.; Yang, X.; Chen, K.; Chan, E.; Yang, M.; Chen, S.

10.1101/2020.01.20.913368 — microbiology — Posted on 2020-01-21

1433 Bioconjugation of AuNPs with HPV 16/18 E6 antibody through physical adsorption technique

Mwai, L. M.; Kyama, M. C.; Ngugi, C. W.; Walong, E.

10.1101/2020.01.21.899930 — cancer biology — Posted on 2020-01-21

1434 Assessment of anesthesia on physiological stability and BOLD signal reliability during visual or acoustic stimulation in the cat

Levine, A. T.; Li, B.; Barnes, P.; Lomber, S. G.; Butler, B. E.

10.1101/827949 — neuroscience — Posted on 2020-01-21

1435 Phylogenetic relationships among haloalkaliphilic archaea of the family Natrialbaceae

Siddaramappa, S.

10.1101/2020.01.20.913392 — microbiology — Posted on 2020-01-21

1436 Deciphering cattle temperament measures derived from a four-platform standing scale using genetic factor analytic modeling

Yu, H.; Morota, G.; Celestino, E. F.; Dahlen, C. R.; Wagner, S. A.; Riley, D. G.; Hulsman Hanna, L. L.

10.1101/2020.01.20.913343 — genetics — Posted on 2020-01-21

1437 Cultural variation impacts paternal and maternal genetic lineages of the 1 Hmong-Mien and Sino-Tibetan groups from Thailand

Kutanan, W.; Shoocongdej, R.; Srikummool, M.; Huebner, A.; Suttipai, T.; Srithawong, S.; Kampuansai, J.; Stoneking, M.

10.1101/2020.01.21.913582 — genetics — Posted on 2020-01-21

1438 Vegetation and seed bank dynamics highlight the importance of post-restoration management in sown grasslands

Valko, O.; Deak, B.; Torok, P.; Toth, K.; Kiss, R.; Kelemen, A.; Miglecz, T.; Sonkoly, J.; Tothmeresz, B.

10.1101/2020.01.20.913426 — ecology — Posted on 2020-01-21

1439 Lessons from Japan marine stock enhancement and sea ranching programmes over 100 years

Kitada, S.

10.1101/828798 — ecology — Posted on 2020-01-21

1440 Small molecule inhibitors and a kinase-dead expressing mouse model demonstrate that the kinase activity of Chk1 is essential for mouse embryos and cancer cells

Muralidharan, S. V.; Nilsson, L. M.; Lindberg, M. F.; Nilsson, J. A.

10.1101/2020.01.21.913467 — cancer biology — Posted on 2020-01-21

1441 Patterns of DNA variation between the autosomes, the X chromosome and the Y chromosome in Bos taurus genome

Czech, B.; Guldbrandtsen, B.; Szyda, J.

10.1101/2020.01.21.901348 — bioinformatics — Posted on 2020-01-21

1442 PathExt: a general framework for path-based mining of omics-integrated biological networks

Chandra, N.; Hannenhalli, S.; Sambaturu, N.; Pusadkar, V.

10.1101/2020.01.21.913418 — systems biology — Posted on 2020-01-21

1443 Discovery of a spatially and temporally persistent core microbiome of the common bean rhizosphere

Stopnisek, N.; Shade, A.

10.1101/2020.01.20.913202 — microbiology — Posted on 2020-01-21

1444 Chinese Glioma Genome Atlas (CGGA): A Comprehensive Resource with Functional Genomic Data for Chinese Glioma Patients

Zhao, Z.; Zhang, K.; Wang, Q.; Li, G.; Zeng, F.; Zhang, Y.; Wu, F.; Chai, R.; Wang, Z.; Zhang, C.; Zhang, W.; Bao, Z.; Jiang, T.

10.1101/2020.01.20.911982 — genomics — Posted on 2020-01-21

1445 The RNA-binding protein, Rasputin/G3BP, enhances the stability and translation of its target mRNAs

Laver, J. D.; Ly, J.; Winn, A. K.; Karaiskakis, A.; Lin, S.; Nie, K.; Benic, G.; Jaberi-Lashkari, N.; Cao, W. X.; Khademi, A.; Westwood, J. T.; Sidhu, S. S.; Morris, Q.; Angers, S.; Smibert, C. A.; Lipshitz, H. D.

10.1101/2020.01.21.913079 — genomics — Posted on 2020-01-21

1446 Single-molecule analysis reveals the role of regulatory light chains in fine-tuning skeletal myosin-II function

Nayak, A.; Wang, T.; Franz, P.; Steffen, W.; Chizhov, I.; Tsiavaliaris, G.; Amrute-Nayak, M.

10.1101/2020.01.21.913558 — biophysics — Posted on 2020-01-21

1447 Single-cell RNA-seq Imputation using Generative Adversarial Networks

Xu, Y.; Zhang, Z.; You, L.; Liu, J.; Fan, Z.; zhou, X.

10.1101/2020.01.20.913384 — bioinformatics — Posted on 2020-01-21

1448 Effect of Perfluorooctanesulfonic acid (PFOS) on immune cell development and function in mice

Torres, L.; Redko, A.; Imbiakha, B.; Limper, C.; Chang, S.; August, A.

10.1101/2020.01.20.913293 — pharmacology and toxicology — Posted on 2020-01-21

1449 Beyond Slam: the DUF560 family outer membrane protein superfamily SPAM has distinct network subclusters that suggest a role in non-lipidated substrate transport and bacterial environmental adaptation

Mauer, T. J.; Grossman, A. S.; Forest, K. T.; Goodrich-Blair, H.

10.1101/2020.01.20.912956 — microbiology — Posted on 2020-01-21

1450 The yeast mating-type switching endonuclease HO is a domesticated member of an unorthodox homing genetic element family

Coughlan, A. Y.; Lombardi, L.; Braun-Galleani, S.; Martos, A. A. R.; Galeote, V.; Bigey, F.; Dequin, S.; Byrne, K. P.; Wolfe, K. H.

10.1101/2020.01.20.913210 — evolutionary biology — Posted on 2020-01-21

1451 A statistical approach for tracking clonal dynamics in cancer using longitudinal next-generation sequencing data

Vavoulis, D. V.; Cutts, A.; Taylor, J. C.; Schuh, A.

10.1101/2020.01.20.913236 — bioinformatics — Posted on 2020-01-21

1452 A distributed neocortical action map associated with reach-to-grasp

Quarta, E.; Scaglione, A.; Lucchesi, J.; Sacconi, L.; Allegra Mascaro, A. L.; Pavone, F. S.

10.1101/2020.01.20.911412 — neuroscience — Posted on 2020-01-21

1453 Fast Lasso method for Large-scale and Ultrahigh-dimensional Cox Model with applications to UK Biobank

Li, R.; Chang, C.; Justesen, J. M.; Tanigawa, Y.; Qian, J.; Hastie, T.; Rivas, M. A.; Tibshirani, R. j.

10.1101/2020.01.20.913194 — bioinformatics — Posted on 2020-01-21

1454 Control tools to selectively produce purple bacteria for microbial protein in raceway reactors

Alloul, A.; Cerruti, M.; Adamczyka, D.; Weissbrodt, D. G.; Vlaeminck, S. E.

10.1101/2020.01.20.912980 — bioengineering — Posted on 2020-01-21

1455 Head Movements Control the Activity of Primary Visual Cortex in a Luminance Dependent Manner

Bouvier, G.; Senzai, Y.; Scanziani, M.

10.1101/2020.01.20.913160 — neuroscience — Posted on 2020-01-21

1456 An Optimized Competitive-Aging Method Reveals Gene-Drug Interactions Underlying the Chronological Lifespan of Saccharomyces cerevisiae

Avelar-Rivas, J. A.; Mungiua-Figueroa, M.; Juarez-Reyes, A.; Garay, E.; Campos, S. E.; Shoresh, N.; DeLuna, A.

10.1101/696682 — genetics — Posted on 2020-01-21

1457 A genome-wide association study finds genetic variants associated with neck or shoulder pain in UK Biobank

Meng, W.; Chan, B. W.; Harris, C.; Freidin, M. B.; Herbert, H. L.; Adams, M. J.; Campbell, A.; Hayward, C.; Zheng, H.; Zhang, X.; Colvin, L. A.; Hales, T. G.; Palmer, C. N.; Williams, F. M.; McIntosh, A. M.; Smith, B. H.

10.1101/2020.01.20.913228 — genetics — Posted on 2020-01-21

1458 Tree diversity and the temporal stability of mountain forest productivity: testing the effect of species composition, through asynchrony and overyielding

JOURDAN, M.; Piedallu, C.; Baudry, J.; Morin, X.

10.1101/2020.01.20.912964 — ecology — Posted on 2020-01-21

1459 Effect of nitrogen on fungal growth efficiency

Di Lonardo, D. P.; van der Wal, A.; Harkes, P.; de Boer, W.

10.1101/2020.01.19.911727 — ecology — Posted on 2020-01-21

1460 PHENSIM: Phenotype Simulator

Alaimo, S.; Marceca, G. P.; La Ferlita, A.; Serebrennikova, O. B.; Tsichlis, P. N.; Pulvirenti, A.; Ferro, A.

10.1101/2020.01.20.912279 — bioinformatics — Posted on 2020-01-21

1461 Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex

Leandro, J.; Khamrui, S.; Wang, H.; Suebsuwong, C.; Nemeria, N. S.; Huynh, K.; Moustakim, M.; Secor, C.; Wang, M.; Dodatko, T.; Stauffer, B.; Wilson, C. G.; Yu, C.; Arkin, M. R.; Jordan, F.; Sanchez, R.; DeVita, R. J.; Lazarus, M. B.; Houten, S. M.

10.1101/2020.01.20.913012 — biochemistry — Posted on 2020-01-21

1462 Tick-Borne bacterial and protozoan animal pathogens shape the native microbiome within Hyalomma anatolicum anatolicum and Rhipicephalus microplus tick vectors

Adegoke, A.; Kumar, D.; Rashid, M. I.; Durrani, A. Z.; Sajid, M. S.; Karim, S.

10.1101/2020.01.20.912949 — zoology — Posted on 2020-01-21

1463 Ligand promiscuity in the tryptophan repressor - from structural understanding towards rational design

Stiel, A. C.; Shanmugaratnam, S.; Herud-Sikimic, O.; Juergens, G.; Hoecker, B.

10.1101/2020.01.20.912972 — synthetic biology — Posted on 2020-01-21

1464 Schisandrin B for treatment of male infertility

zou, D.-X.; Meng, X.-D.; Xie, Y.; Liu, R.; Duan, J.-L.; Bao, C.-J.; Liu, Y.-X.; Du, Y.-F.; Xu, J.-R.; Luo, Q.; Zhang, Z.; Ma, S.; Yang, W.-P.; Lin, R.-C.; Lu, W.-L.

10.1101/2020.01.20.912147 — pharmacology and toxicology — Posted on 2020-01-21

1465 Plxdc family members are novel receptors for the rhesus monkey rhadinovirus (RRV)

Grosskopf, A. K.; Schlagowski, S. C.; Ensser, A.; Desrosiers, R. C.; Hahn, A. S.

10.1101/2020.01.20.912246 — microbiology — Posted on 2020-01-21

1466 A sister lineage of the Mycobacterium tuberculosis complex discovered in the African Great Lakes region

Semuto Ngabonziza, J. C.; Loiseau, C.; Marceau, M.; Jouet, A.; Menardo, F.; Tzfadia, O.; Niyigena, E. B.; Mulders, W.; Fissette, K.; Diels, M.; Gaudin, C.; Duthoy, S.; Ssengooba, W.; Andre, E.; Kaswa, M. K.; Mucyo Habimana, Y.; Brites, D.; Affolabi, D.; Mazarati, J. B.; de Jong, B. C.; Rigouts, L.; Gagneux, S.; Meehan, C. J.; Supply, P. J.

10.1101/2020.01.20.912998 — microbiology — Posted on 2020-01-21

1467 CASSPER: A Semantic Segmentation based Particle Picking Algorithm for Single Particle Cryo-Electron Microscopy

George, B.; Assaiya, A.; Roy, R. J.; Kembhavi, A.; Chauhan, R. D.; Paul, G.; Kumar, J.; Philip, N. S.

10.1101/2020.01.20.912139 — biophysics — Posted on 2020-01-21

1468 Static and Dynamic Aspects of Cerebro-Cerebellar Functional Connectivity are Associated with Self-reported Measures of Impulsivity: A Resting-State fMRI Study

Abdallah, M.; Farrugia, N.; Chirokoff, V.; Chanraud, S.

10.1101/2020.01.20.912295 — neuroscience — Posted on 2020-01-21

1469 Immunohistochemical Characterization of Phosphorylated Ubiquitin in the Mouse Hippocampus

Kataoka, K.; Bilkei-Gorzo, A.; Zimmer, A.; Asahi, T.

10.1101/2020.01.20.912238 — neuroscience — Posted on 2020-01-21

1470 Spatial receptive field structure of double-opponent and simple cells in macaque primary visual cortex

De, A.; Horwitz, G. D.

10.1101/2020.01.20.913111 — neuroscience — Posted on 2020-01-21

1471 No support for the adaptive hypothesis of lagging-strand encoding in bacterial genomes

Liu, H.; Zhang, J. G.

10.1101/2020.01.14.906818 — evolutionary biology — Posted on 2020-01-21

1472 Is cathodal prefrontal transcranial direct current stimulation capable of affecting inhibitory control and sustained attention? A single-blind, crossover,sham-controlled study

Canabarro, S. L. d. S.; Paniago, C. K.; Santos, P. M.; Rosa, L. S.; Borges, V. E. L.; McManus, D. P.; Garcia, A.; Satler, C.; Brasil-Neto, J. P.; Tavares, M. C. H.

10.1101/2020.01.20.912287 — neuroscience — Posted on 2020-01-21

1473 A Bayesian nonparametric semi-supervised model for integration of multiple single-cell experiments

Verma, A.; Engelhardt, B. E.

10.1101/2020.01.14.906313 — bioinformatics — Posted on 2020-01-21

1474 Deciphering the Signaling Network Landscape of Breast Cancer Improves Drug Sensitivity Prediction

Tognetti, M.; Gabor, A.; Yang, M.; Cappelletti, V.; Windhager, J.; Charmpi, K.; de Souza, N.; Beyer, A.; Picotti, P.; Saez-Rodriguez, J.; Bodenmiller, B.

10.1101/2020.01.21.907691 — systems biology — Posted on 2020-01-21

1475 Clustered γ-Protocadherins Regulate Cortical Interneuron Programmed Cell Death.

Mancia Leon, W. R.; Spatazza, J.; Rakela, B.; Chatterjee, A.; Pande, V.; Maniatis, T.; Hasenstaub, A. R.; Stryker, M. P.; Alvarez-Buylla, A.

10.1101/2020.01.14.906941 — neuroscience — Posted on 2020-01-21

1476 Insulin signaling mediates neurodegeneration in glioma

Jarabo, P.; de Pablo, C.; Herranz, H.; Martin, F. A.; Casas-Tinto, S.

10.1101/2020.01.03.894469 — neuroscience — Posted on 2020-01-21

1477 Modeling confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit Aedes aegypti populations

Sanchez C., H. M.; Bennett, J. B.; Wu, S. L.; Rasic, G.; Akbari, O. S.; Marshall, J. M.

10.1101/607267 — ecology — Posted on 2020-01-21

1478 Bovine breed-specific augmented reference graphs facilitate accurate sequence read mapping and unbiased variant discovery

Crysnanto, D.; Pausch, H.

10.1101/2019.12.20.882423 — genomics — Posted on 2020-01-21

1479 Mechanism and site of action of big dynorphin on ASIC1a

Borg, C. B.; Braun, N.; Heusser, S. A.; Bay, Y.; Weis, D.; Galleano, I.; Lund, C.; Tian, W.; Haugaard-Kedstroem, L. M.; Bennett, E. P.; Lynagh, T.; Stromgaard, K.; Andersen, J.; Pless, S.

10.1101/816264 — biophysics — Posted on 2020-01-21

1480 A bright and high-performance genetically encoded Ca2+ indicator based on mNeonGreen fluorescent protein

Zarowny, L.; Aggarwal, A.; Rutten, V. M. S.; Kolb, I.; The GENIE Project, ; Patel, R.; Huang, H.-Y.; Chang, Y.-F.; Phan, T.; Kanyo, R.; Ahrens, M.; Allison, W. T.; Podgorski, K.; Campbell, R. E.

10.1101/2020.01.16.909291 — molecular biology — Posted on 2020-01-21

1481 Increased likelihood of heat-induced large wildfires in the Mediterranean Basin

Ruffault, J.; Curt, T.; Moron, V.; Trigo, R.; Mouillot, F.; Koutsias, N.; Pimont, F.; Martin-StPaul, N.; Barbero, R.; Dupuy, J.-L.; Russo, A.; Belhadj-Kheder, C.

10.1101/2020.01.09.896878 — ecology — Posted on 2020-01-21

1482 Hybrid Pharmacophore Approach as a Novel Strategy to identify Anti-Mycobacterial Chemotypes: Investigation with DapB Enzyme

Bhardwaj, A.; Choudhury, C.

10.1101/2020.01.20.912063 — bioinformatics — Posted on 2020-01-21

1483 The optoretinogram reveals how human photoreceptors deform in response to light

Pandiyan, V. P.; Bertelli, A. M.; Kuchenbecker, J.; Boyle, K. C.; Ling, T.; Park, B. H.; Roorda, A.; Palanker, D.; Sabesan, R.

10.1101/2020.01.18.911339 — neuroscience — Posted on 2020-01-21

1484 A novel ribosomal protein S20 variant in a family with unexplained colorectal cancer and polyposis

Thompson, B. A.; Snow, A. K.; Koptiuch, C.; Kohlmann, W. K.; Mooney, R.; Johnson, S.; Huff, C.; Yu, Y.; Teerlink, C. C.; Feng, B.-J.; Neklason, D. W.; Cannon-Albright, L. A.; Tavtigian, S. V.

10.1101/2019.12.16.877084 — genetics — Posted on 2020-01-21

1485 Assessing the accuracy of octanol-water partition coefficient predictions in the SAMPL6 Part II log P Challenge

Isık, M.; Bergazin, T. D.; Fox, T.; Rizzi, A.; Chodera, J. D.; Mobley, D. L.

10.1101/2020.01.20.913178 — biophysics — Posted on 2020-01-21

1486 Heterogeneity in VEGF Receptor-2 mobility and organization on the endothelial cell surface leads to diverse activation models by VEGF

da Rocha-Azevedo, B.; Lee, S.; Dasgupta, A.; Vega, A. R.; de Oliveira, L. R.; Kim, T.; Kittisopikul, M.; Jaqaman, K.

10.1101/800946 — biophysics — Posted on 2020-01-21

1487 LuxHS: DNA methylation analysis with spatially varying correlation structure

Halla-aho, V.; Lähdesmäki, H.

10.1101/2020.01.21.913640 — bioinformatics — Posted on 2020-01-21

1488 Competitive dominance in plant communities: Modeling approaches and theoretical predictions

Capitan, J. A.; Cuenda, S.; Alonso, D.

10.1101/2020.01.20.913277 — ecology — Posted on 2020-01-21

1489 Sort-purification of human CD34+CD90+ cells reduces target cell population and improves lentiviral transduction

Radtke, S.; Pande, D.; Cui, M.; Perez, A. M.; Chan, Y.-Y.; Enstrom, M.; Schmuck, S.; Berger, A.; Eunson, T.; Adair, J. E.; Kiem, H.-P.

10.1101/850479 — cell biology — Posted on 2020-01-21

1490 Analyzing kinetic signaling data for G-protein-coupled receptors

Hoare, S. R. J.; Tewson, P. H.; Quinn, A. M.; Hughes, T. E.; Bridge, L. J.

10.1101/2020.01.20.913319 — pharmacology and toxicology — Posted on 2020-01-21

1491 Machine learning based imputation techniques for estimating phylogenetic trees from incomplete distance matrices

Bhattacharjee, A.; Bayzid, M. S.

10.1101/744789 — genomics — Posted on 2020-01-21

1492 Middle-level IM-MS and CIU experiments for improved therapeutic immunoglobulin isotype fingerprinting

Botzanowski, T.; HERNANDEZ-ALBA, O.; Malissard, M.; Wagner-Rousset, E.; Desligniere, E.; Colas, O.; Haeuw, J.-F.; Beck, A.; CIANFERANI, S.

10.1101/2020.01.20.911750 — biophysics — Posted on 2020-01-21

1493 System-wide Identification and prioritization of Enzyme Substrates by Thermal Analysis (SIESTA)

Saei, A. A.; Beusch, C.; Sabatier, P.; Astorga Wells, J.; Chernobrovkin, A.; Rodin, S.; Nareoja, K.; Thorsell, A.-G.; Karlberg, T.; Cheng, Q.; Lundstrom, S. L.; Gaetani, M.; Vegvari, A.; Arner, E. S. J.; Schuler, H.; Zubarev, R.

10.1101/423418 — biochemistry — Posted on 2020-01-21

1494 Third-party prosocial behavior in adult female rats is impaired after perinatal fluoxetine exposure

Heinla, I.; Heijkoop, R.; Houwing, D. J.; Olivier, J. D. A.; Snoeren, E. M. S.

10.1101/763276 — animal behavior and cognition — Posted on 2020-01-21

1495 Effect of flagellar beating pattern on sperm rheotaxis and boundary-dependent navigation

Zaferani, M.; Javi, F.; Mokhtare, A.; Abbaspourrad, A.

10.1101/2020.01.20.913145 — biophysics — Posted on 2020-01-21

1496 Ursodeoxycholic acid (UDCA) mitigates the host inflammatory response during Clostridioides difficile infection by altering gut bile acids which attenuates NF-κB signaling via bile acid activated receptors

Winston, J. A.; Rivera, A. M.; Cai, J.; Thanissery, R. M.; Montgomery, S. A.; Patterson, A. D.; Theriot, C. M.

10.1101/2020.01.16.910018 — microbiology — Posted on 2020-01-21

1497 Polynomial-Time Statistical Estimation of Species Trees under Gene Duplication and Loss

Legried, B.; Molloy, E. K.; Warnow, T.; Roch, S.

10.1101/821439 — evolutionary biology — Posted on 2020-01-21

1498 Graph biased feature selection of genes is better than random for many genes

Crawford, J.; Greene, C. S.

10.1101/2020.01.17.910703 — bioinformatics — Posted on 2020-01-21

1499 Bidirectional transfer of Engrailed homeoprotein across the plasma membrane requires PIP2

Amblard, I.; Dupont, E.; Alves, i.; Miralves, J.; Queguiner, I.; JOLIOT, A.

10.1101/2020.01.21.913566 — cell biology — Posted on 2020-01-21

1500 Drosophila dTBCE recruits tubulin around chromatin to promote mitotic spindle assembly

Metivier, M.; Gallaud, E.; Pascal, A.; Gagne, J.-P.; Poirier, G.; Chretien, D.; Gibeaux, R.; Richard-Parpaillon, L.; Benaud, C.; Giet, R.

10.1101/2020.01.21.912428 — cell biology — Posted on 2020-01-21

1501 Lipid Sponge Droplets as Programmable Synthetic Organelles

Bhattacharya, A.; Niederholtmeyer, H.; Podolsky, K. A.; Bhattacharya, R.; Song, J.-J.; Brea, R. J.; Tsai, C.-H.; Sinha, S. K.; Devaraj, N. K.

10.1101/2020.01.20.913350 — synthetic biology — Posted on 2020-01-21

1502 Connectomics analysis reveals first, second, and third order thermosensory and hygrosensory neurons in the adult Drosophila brain

10.1101/2020.01.20.912709 — neuroscience — Posted on 2020-01-21

1503 Serotonin signaling by maternal neurons upon stress ensures progeny survival

Das, S.; Ooi, F. K.; Cruz Corchado, J.; Fuller, L. C. C.; Weiner, J. A.; Prahlad, V.

10.1101/2020.01.20.913038 — cell biology — Posted on 2020-01-21

1504 The cell-cell adhesion protein JAM3 determines nuclear deformability by regulating microtubule organization

Arias-Garcia, M.; Rickman, R.; Sero, J.; Yuan, Y.; Bakal, C.

10.1101/689737 — cell biology — Posted on 2020-01-21

1505 vLUME: 3D Virtual Reality for Single-molecule Localization Microscopy

Spark, A.; Kitching, A.; Esteban-Ferrer, D.; Handa, A.; Carr, A. R.; Needham, L.-M.; Ponjavic, A.; Da Cunha Santos, M.; McColl, J.; Leterrier, C.; Davis, S. J.; Henriques, R.; Lee, S. F.

10.1101/2020.01.20.912733 — biophysics — Posted on 2020-01-21

1506 The persistence in time of distributional patterns in marine megafauna impacts zonal conservation strategies

Lambert, C.; Doremus, G.; Ridoux, V.

10.1101/790634 — ecology — Posted on 2020-01-21

1507 Single-cell analysis of a mutant library generated using CRISPR-guided deaminase

Jun, S.; Lim, H.; Chun, H.; Lee, J. H.; Bang, D.

10.1101/610725 — bioengineering — Posted on 2020-01-21

1508 Singular manifolds of proteomic drivers to model the evolution of inflammatory bowel disease status

Morilla, I.; Leger, T.; Marah, A.; Pic, I.; Zaag, H.; Ogier-Denis, E.

10.1101/751289 — systems biology — Posted on 2020-01-21

1509 Gene expression in isolated cowpea (Vigna unguiculata L. Walp) cells from meiosis to seed initiation

Gursanscky, N. R.; Mazurkiewicz, D.; Juranic, M.; Johnson, S. D.; Leon, G.; Escobar-Guzman, R.; Salinas-Gamboa, R.; Amasende-Morales, I.; Riboni, M.; Hand, M.; Spriggs, A.; Vielle-Calzada, J.-P.; Koltunow, A. M. G.

10.1101/2020.01.17.909945 — plant biology — Posted on 2020-01-21

1510 The brain of a nocturnal migratory insect, the Australian Bogong moth

Adden, A.; Wibrand, S.; Pfeiffer, K.; Warrant, E.; Heinze, S.

10.1101/810895 — neuroscience — Posted on 2020-01-21

1511 KAT2-mediated acetylation switches the mode of PALB2 chromatin association to safeguard genome integrity

Fournier, M.; Bleuyard, J.-Y.; Couturier, A. M.; Ellins, J.; Hester, S.; Smerdon, S. J.; Tora, L.; Esashi, F.

10.1101/735811 — cell biology — Posted on 2020-01-21

1512 Poor Quality Vβ Recombination Signal Sequences Enforce TCRβ Allelic Exclusion by Limiting the Frequency of Vβ Recombination

Wu, G. S.; Yang-Iott, K. S.; Reed, M. A.; Hayer, K. E.; Lee, K. D.; Bassing, C. H.

10.1101/2020.01.20.913046 — immunology — Posted on 2020-01-21

1513 Identification of novel, clinically correlated autoantigens in the monogenic autoimmune syndrome APS1 by PhIP-Seq

Vazquez, S. E.; Ferre, E. M. N.; Scheel, D. W.; Sunshine, S.; Miao, B.; Mandel-Brehm, C.; Quandt, Z.; Chan, A. Y.; Cheng, M.; German, M. S.; Lionakis, M. S.; DeRisi, J. L.; Anderson, M. S.

10.1101/2020.01.20.913186 — immunology — Posted on 2020-01-21

1514 Selective germline genome edited pigs and their long immune tolerance in Non Human Primates

Zou, L.; Zhang, Y.; He, Y.; Yu, H.; Chen, J.; Liu, D.; Lin, S.; Gao, M.; Zhong, G.; Lei, W.; Zhou, G.; Zou, X.; Li, K.; Yin, Y.; Zha, G.; Li, L.; Zeng, Y.; Wang, J.; Wang, G.

10.1101/2020.01.20.912105 — synthetic biology — Posted on 2020-01-21

1515 Supramodal selective attention differentially adjusts frequency and phase of entrained oscillations in primary sensory areas and frontoparietal areas

Suess, N.; Hartmann, T.; Weisz, N.

10.1101/697615 — neuroscience — Posted on 2020-01-21

1516 Inferring a simple mechanism for alpha-blocking by fitting a neural population model to EEG spectra

Hartoyo, A.; Cadusch, P.; Liley, D.; Hicks, D.

10.1101/2020.01.20.912386 — neuroscience — Posted on 2020-01-21

1517 Lung type II alveolar epithelial cells collaborate with CCR2+ inflammatory monocytes in host defense against an acute vaccinia infection in the lungs

Yang, N.; Luna, J. M.; Dai, P.; Wang, Y.; Rice, C. M.; Deng, L.

10.1101/2020.01.20.910927 — immunology — Posted on 2020-01-21

1518 BREM-SC: A Bayesian Random Effects Mixture Model for Joint Clustering Single Cell Multi-omics Data

Wang, X.; Sun, Z.; Zhang, Y.; Xu, Z.; Huang, H.; Duerr, R. H.; Chen, K.; Ding, Y.; Chen, W.

10.1101/2020.01.18.911461 — genomics — Posted on 2020-01-21

1519 Wing shape and environmental energy are associated with molecular evolutionary rates in a large avian radiation

Duchene, D. A.; Montoya, P.; Cadena, D. A.

10.1101/2020.01.16.908368 — evolutionary biology — Posted on 2020-01-21

1520 Interaction of 14-3-3I and CDPK1 mediates the growth of human malaria parasite

Jain, R.; Dey, P.; Gupta, S.; Pati, S.; Bhattacherjee, A.; Munde, M.; Singh, S.

10.1101/2020.01.14.906479 — cell biology — Posted on 2020-01-21

1521 Deciphering the regulatory genome of Escherichiacoli, one hundred promoters at a time

Ireland, W. T.; Beeler, S. M.; Flores-Bautista, E.; Belliveau, N. M.; Sweredoski, M. J.; Moradian, A.; Kinney, J. B.; Phillips, R.

10.1101/2020.01.18.910323 — biophysics — Posted on 2020-01-21

1522 Identifying and engineering ancient variants of enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP)

Foley, G.; Mora, A.; Ross, C. M.; Bottoms, S.; Sutzl, L.; Lamprecht, M. L.; Zaugg, J.; Essebier, A.; Balderson, B.; Newell, R.; Thomson, R. E.; Kobe, B.; Barnard, R. T.; Guddat, L.; Schenk, G.; Carsten, J.; Gumulya, Y.; Rost, B.; Haltrich, D.; Sieber, V.; Gillam, E. M.; Boden, M.

10.1101/2019.12.30.891457 — bioinformatics — Posted on 2020-01-21

1523 The connector between the kinase and RNase domains of IRE1α transmits the conformational change that underlies ER stress-induced activation.

Ricci, D.; Tutton, S.; Marrocco, I.; Ying, M.; Blumenthal, D.; Eletto, D.; Vargas, J.; Boyle, S.; Fazelinia, H.; Paton, J. C.; Paton, A. W.; Tang, C.-H. A.; Hu, C.-C. A.; Gidalevitz, T.; Argon, Y.

10.1101/2020.01.14.902395 — biochemistry — Posted on 2020-01-21

1524 The rebound response plays a role in the motion mechanisms and perception

Cohen-Duwek, H.; Spitzer, H.

10.1101/2019.12.31.891580 — neuroscience — Posted on 2020-01-21

1525 A Method for Harmonizing Longitudinal Multi-scanner Imaging Data

Beer, J. C.; Tustison, N. J.; Cook, P. A.; Sheline, Y. I.; Shinohara, R. T.; Linn, K. A.

10.1101/868810 — neuroscience — Posted on 2020-01-21

1526 Investigating the impact of combination phage and antibiotic therapy: a modeling study

Banuelos, S.; Gulbudak, H.; Horn, M. A.; Huang, Q.; Nandi, A.; Ryu, H.; Segal, R.

10.1101/2020.01.08.899476 — microbiology — Posted on 2020-01-21

1527 Interplay between the paradox of enrichment and nutrient cycling in food webs

Quevreux, P.; Barot, S.; Thebault, E.

10.1101/276592 — ecology — Posted on 2020-01-21

1528 Visualization and Analysis of the Interaction Network of Proteins Associated with Blood-cell targeting Autoimmune Diseases

Amanatidou, A. I.; Nastou, K. C.; Tsitsilonis, O. E.; Iconomidou, V. A.

10.1101/763672 — bioinformatics — Posted on 2020-01-21

1529 The optoretinogram reveals how human photoreceptors deform in response to light

Pandiyan, V. P.; Bertelli, A. M.; Kuchenbecker, J.; Boyle, K. C.; Ling, T.; Park, B. H.; Roorda, A.; Palanker, D.; Sabesan, R.

10.1101/2020.01.18.911339 — neuroscience — Posted on 2020-01-21

1530 DIALib: an automated ion library generator for data independent acquisition mass spectrometry analysis of peptides and glycopeptides

Phung, T. K.; Zacchi, L. F.; Schulz, B. L.

10.1101/696518 — bioinformatics — Posted on 2020-01-21

1531 Glycoproteomic measurement of site-specific polysialylation

Pelingon, R.; Pegg, C. L.; Zacchi, L. F.; Phung, T. K.; Howard, C. B.; Xu, P.; Hardy, M. P.; Owczarek, C. M.; Schulz, B. L.

10.1101/740928 — biochemistry — Posted on 2020-01-21

1532 A confirmation bias in perceptual decision-making due to hierarchical approximate inference

Lange, R. D.; Chattoraj, A.; Beck, J.; Yates, J.; Haefner, R.

10.1101/440321 — animal behavior and cognition — Posted on 2020-01-21

1533 Production location of the gelling agent Phytagel has a significant impact on Arabidopsis thaliana seedling phenotypic analysis

Jacques, C. N.; Hulbert, A. K.; Westenskow, S.; Neff, M. M.

10.1101/2020.01.20.912501 — plant biology — Posted on 2020-01-20

1534 An Innovative Setup for High-Throughput Respirometry of Small Aquatic Animals

Drown, M.; DeLiberto, A. N.; Crawford, D. L.; Oleksiak, M. F.

10.1101/2020.01.20.912469 — physiology — Posted on 2020-01-20

1535 Neurons from human mesenchymal stem cells display both spontaneous and stimuli responsive activity

Karakas, N.; Bay, S.; Turkel, N.; Öncül, M.; Bilgen, H.; Shah, K.; Sahin, F.; Öztürk, G.

10.1101/2020.01.20.912394 — neuroscience — Posted on 2020-01-20

1536 Inferring a simple mechanism for alpha-blocking by fitting a neural population model to EEG spectra

Hartoyo, A.; Cadusch, P.; Liley, D.; Hicks, D.

10.1101/2020.01.20.912386 — neuroscience — Posted on 2020-01-20

1537 Optimal spectral templates for triggered feedback experiments

Kulkarni, A. S.; Troyer, T. W.

10.1101/2020.01.20.912444 — neuroscience — Posted on 2020-01-20

1538 Inhibitory effects of Akt on neuronal FoxO4 activation after subarachnoid hemorrhage in vivo and in vitro

Qi, M.; Gao, S.-q.; Liu, J.-q.; Han, Y.-l.; Yuan, B.; Zhou, X.-m.; Liu, X.-l.; Zhou, M.-l.; Zheng, L.-r.

10.1101/2020.01.20.912436 — neuroscience — Posted on 2020-01-20

1539 An electrodiffusive, ion conserving Pinsky-Rinzel model with homeostatic mechanisms

Saetra, M. J.; Einevoll, G. T.; Halnes, G.

10.1101/2020.01.20.912378 — neuroscience — Posted on 2020-01-20

1540 Innate immune gene expression in Acropora palmata is consistent despite variance in yearly disease events

Young, B. D.; Serrano, X.; Rosales, S.; Miller, M.; Williams, D.; Traylor-Knowles, N.

10.1101/2020.01.20.912410 — molecular biology — Posted on 2020-01-20

1541 A single nonsynonymous mutation on gene encoding E protein of Zika virus leads to increased neurovirulence in vivo

Liu, Z.; Zhang, Y.; Cheng, M.; Ge, N.; Shu, J.; Xu, Z.; Tong, Y.; Qin, C.; Jin, X.

10.1101/2020.01.20.912535 — microbiology — Posted on 2020-01-20

1542 A partial pathogenicity chromosome in Fusarium oxysporum is sufficient to cause disease and can be horizontally transferred

Li, J.; Fokkens, L.; Conneely, L. J.; Rep, M.

10.1101/2020.01.20.912550 — microbiology — Posted on 2020-01-20

1543 Glutamate dehydrogenase (Gdh2)-dependent alkalization is dispensable for escape from macrophages and virulence of Candida albicans

Silao, F. G. S.; Ryman, K.; Jiang, T.; Ward, M.; Hansmann, N.; Liu, N.-N.; Chen, C.; Ljungdahl, P. O.

10.1101/2020.01.20.912592 — microbiology — Posted on 2020-01-20

1544 Naïve CD8 T cell IFNγ responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5

Kongsomboonvech, A. K.; Rodriguez, F.; Diep, A. L.; Justice, B. M.; Castallanos, B. E.; Camejo, A.; Mukhopadhyay, D.; Taylor, G. A.; Yamamoto, M.; Saeij, J. P. J.; Reese, M. L.; Jensen, K.

10.1101/2020.01.20.912568 — immunology — Posted on 2020-01-20

1545 Bacillus subtilis spore induces efficient generation of memory T cells via ICAM-1 expression on dendritic cells

Huang, L.; Lin, J.; Li, Y.; Zhang, P.; Yu, Q.; Yang, Q.

10.1101/2020.01.20.912584 — immunology — Posted on 2020-01-20

1546 Search for and function of different genes in phloem and xylem of poplar

Li, X.; Jiang, X.

10.1101/2020.01.20.912493 — bioinformatics — Posted on 2020-01-20

Mikat, M.; Benda, D.; Straka, J.

10.1101/2020.01.20.912519 — evolutionary biology — Posted on 2020-01-20

1548 Application of Pedimap -- a pedigree visualization tool -- to facilitate the decisioning of rice breeding in Sri Lanka

Rathnayake, P.; Sahibdeen, S.; Udawela, U.; Weebadde, C.; Weerakoon, W.; Sooriyapathirana, S.

10.1101/2020.01.20.912477 — genetics — Posted on 2020-01-20

1549 CRISPR/Cas with ribonucleoprotein complexes and transiently selected telomere vectors allows highly efficient marker-free and multiple genome editing in Botrytis cinerea

Hahn, M.; Leisen, T.; Bietz, F.; Werner, J.; Wegner, A.; Schaffrath, U.; Scheuring, D.; Willmund, F.; Mosbach, A.; Scalliet, G.

10.1101/2020.01.20.912576 — genetics — Posted on 2020-01-20

1550 Lipidomics of human adipose tissue reveals diversity between body areas

Al-Sari, N.; Suvitaival, T.; Mattila, I.; Ali, A.; Ahonen, L.; Trost, K.; Henriksen, T. F.; Pociot, F.; Dragsted, L. O.; Legido-Quigley, C.

10.1101/2020.01.20.912527 — biophysics — Posted on 2020-01-20

1551 EnhancerP-2L: A Gene regulatory site identification tool for DNA enhancer region using CREs motifs

Butt, A. H.; Alkhalaf, S.; Iqbal, S.; Khan, Y. D.

10.1101/2020.01.20.912451 — bioinformatics — Posted on 2020-01-20

1552 Compressive Big Data Analytics: An Ensemble Meta-Algorithm for High-dimensional Multisource Datasets

Marino, S.; Zhao, Y.; Zhou, N.; Zhou, Y.; Toga, A.; Zhao, L.; Jian, Y.; Chen, Y.; Wu, Q.; Wild, J.; Cummings, B.; Dinov, I.

10.1101/2020.01.20.912485 — bioinformatics — Posted on 2020-01-20

1553 Use of Transabdominal Ultrasound for the Detection of Intra-Peritoneal Tumor Engraftment and Growth in Mouse Xenografts of Epithelial Ovarian Cancer

Chambers, L.; Esakov, E.; Braley, C.; AlHilli, M.; Michener, C.; Reizes, O.

10.1101/2020.01.20.912402 — cancer biology — Posted on 2020-01-20

1554 Vacuolar sucrose homeostasis is critical for development, seed properties and survival of dark phases of Arabidopsis

Vu, D. P.; Martins Rodrigues, C.; Jung, B.; Meissner, G.; Klemens, P. A. W.; Holtgräwe, D. L.; Fürtauer, L.; Nägele, T.; Nieberl, P.; Pommerrenig, B.; Neuhaus, H. E.

10.1101/2020.01.20.912253 — plant biology — Posted on 2020-01-20

1555 Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism

Bezerra, G. A.; Foster, W. R.; Bailey, H. J.; Hicks, K. G.; Sauer, S. W.; Dimitrov, B.; Okun, J. G.; Rutter, J.; Koelker, S.; Yue, W. W.

10.1101/2020.01.20.912931 — biochemistry — Posted on 2020-01-20

1556 NEURAL OSCILLATIONS DISSOCIATE BETWEEN MAINTENANCE AND PROCEDURALIZATION OF NOVEL INSTRUCTIONS

Formica, S.; Gonzalez-Garcia, C.; Senoussi, M.; Brass, M.

10.1101/2020.01.20.912162 — neuroscience — Posted on 2020-01-20

1557 NREM consolidation and increased spindle counts improve age-related memory impairments and hippocampal representations

Yuan, R. K.; Lopez, M. R.; Normandin, M. E.; Thomas, A. S.; Cerda, V. R.; Grenier, A. E.; Wood, M. T.; Gagliardi, C. M.; Muzzio, I. A.

10.1101/2020.01.20.912915 — neuroscience — Posted on 2020-01-20

1558 CryoEM structure of the Nipah virus nucleocapsid assembly

Ker, D.-S.; Jenkins, H. T.; Greive, S. J.; Antson, A. A.

10.1101/2020.01.20.912261 — biophysics — Posted on 2020-01-20

1559 A super sensitive auxin-inducible degron system with an engineered auxin-TIR1 pair

Nishimura, K.; Yamada, R.; Hagihara, S.; Iwasaki, R.; Uchida, N.; Kamura, T.; Takahashi, K.; Torii, K. U.; Fukagawa, T.

10.1101/2020.01.20.912113 — bioengineering — Posted on 2020-01-20

1560 ILoReg enables high-resolution cell population identification from single-cell RNA-seq data

Smolander, J.; Junttila, S.; Venäläinen, M. S.; Elo, L. L.

10.1101/2020.01.20.912675 — bioinformatics — Posted on 2020-01-20

1561 CAM emerges in a leaf metabolic model under water-saving constraints in different environments

Toepfer, N.; Braam, T.; Shameer, S.; Ratcliffe, R. G.; Sweetlove, L. J.

10.1101/2020.01.20.912782 — plant biology — Posted on 2020-01-20

1562 Barley shoot biomass responds strongly to N:P stoichiometry and intraspecific competition, whereas roots only alter their foraging

Kumar, A.; van Duijnen, R.; Delory, B. M.; Reichel, R.; Brueggemann, N.; Temperton, V. M.

10.1101/2020.01.20.912352 — plant biology — Posted on 2020-01-20

1563 Acetylcholine prioritises direct synaptic inputs from entorhinal cortex to 1 CA1 by differential modulation of feedforward inhibitory circuits

Palacios-Filardo, J.; Udakis, M.; Brown, G. A.; Tehan, B. G.; Congreve, M. S.; Nathan, P. J.; Brown, A. J. H.; Mellor, J.

10.1101/2020.01.20.912873 — neuroscience — Posted on 2020-01-20

1564 The Developing Human Connectome Project: typical and disrupted functional connectivity across the perinatal period

10.1101/2020.01.20.912881 — neuroscience — Posted on 2020-01-20

1565 Human POT1 Prevents Severe Telomere Instability Induced by Homology Directed DNA Repair

Glousker, G.; Briod, A.-S.; Quadroni, M.; Lingner, J.

10.1101/2020.01.20.912642 — molecular biology — Posted on 2020-01-20

1566 Deep learning for population size history inference: design, comparison and combination with approximate Bayesian computation

Sanchez, T.; Cury, J.; Charpiat, G.; Jay, F.

10.1101/2020.01.20.910539 — evolutionary biology — Posted on 2020-01-20

1567 Urban colonization is driven by a mixture of evolutionarily conserved and labile traits

Duchene, D. A.; Pardo-Diaz, C.; Iglesias-Carrasco, M.

10.1101/2020.01.20.912170 — evolutionary biology — Posted on 2020-01-20

1568 Specialisation of ribosomes in gonads through paralog-switching

Aspden, J. L.; Fontana, J.; O'Connell, M. J.; McCarthy, C. G.; Norris, K.; Agapiou, M.; Hopes, T. S.

10.1101/2020.01.20.913020 — biochemistry — Posted on 2020-01-20

1569 Single-nucleus RNA-Seq reveals a new type of brown adipocyte regulating thermogenesis

Sun, W.; Dong, H.; Balaz, M.; Slyper, M.; Drokhlyansky, E.; Colleluori, G.; Giordano, A.; Kovanicova, Z.; Stefanicka, P.; Ding, L.; Rudofsky, G.; Ukropec, J.; Cinti, S.; Regev, A.; Wolfrum, C.

10.1101/2020.01.20.890327 — cell biology — Posted on 2020-01-20

1570 Underground deserts below fertility islands? - Woody species desiccate lower soil layers in sandy drylands

Tolgyesi, C.; Torok, P.; Habenczyus, A. A.; Batory, Z.; Orsolya, V.; Deak, B.; Tothmeresz, B.; Erdos, L.; Kelemen, A.

10.1101/2020.01.20.912220 — ecology — Posted on 2020-01-20

1571 Cell size regulation in budding yeast does not depend on linear accumulation of Whi5

Barber, F.; Amir, A.; Murray, A. W.

10.1101/2020.01.20.912832 — cell biology — Posted on 2020-01-20

1572 Cocaine triggers glial-mediated synaptogenesis

Wang, J.; Li, K.-L.; Shukla, A.; Beroun, A.; Ishikawa, M.; Huang, X.; Wang, Y.; Wang, Y. Q.; Bastola, N. D.; Huang, H. H.; Kramer, L. E.; Chao, T.; Huang, Y. H.; Sesack, S. R.; Nestler, E. J.; Schluter, O. M.; Dong, Y.

10.1101/2020.01.20.896233 — neuroscience — Posted on 2020-01-20

1573 Creating supported plasma membrane bilayers using acoustic pressure

Sezgin, E.; Carugo, D.; Levental, I.; Stride, E.; Eggeling, C.

10.1101/2020.01.20.912840 — biophysics — Posted on 2020-01-20

1574 Mechanochemical modelling of dorsal closure reveals emergent cell behaviour in tissue morphogenesis

Atzeni, F.; Pasakarnis, L.; Moscsa, G.; Smith, R.; Aegerter, C.; Brunner, D.

10.1101/2020.01.20.912725 — systems biology — Posted on 2020-01-20

1575 Building the lac operon: A guided-inquiry activity using 3D printed models

Gordy, C. L.; Sandefur, C. I.; Lacara, T.; Harris, F. R.; Ramirez, M. V.

10.1101/2020.01.14.904847 — scientific communication and education — Posted on 2020-01-20

1576 Role of prefrontal cortex projections to the nucleus accumbens core in mediating the effects of ceftriaxone on cued cocaine relapse

Bechard, A. R.; Logan, C. N.; Mesa, J.; Padovan Hernandez, Y.; Blount, H.; Hodges, V.; Knackstedt, L. A.

10.1101/2020.01.20.911792 — neuroscience — Posted on 2020-01-20

1577 Structural determinants of dynamic fluctuations between segregation and integration on the human connectome

Fukushima, M.; Sporns, O.

10.1101/2020.01.20.912030 — neuroscience — Posted on 2020-01-20

1578 RADX Sustains POT1 Function at Telomeres to Counteract RAD51 Binding, which Triggers Telomere Fragility

Lingner, J.; Glousker, G.; Briod, A.-S.

10.1101/2020.01.20.912634 — molecular biology — Posted on 2020-01-20

1579 Genetic diversity evaluation among fifty sugarcane accessions from the Zimbabwe Sugar Industry using DNA-SSR markers and qualitative traits.

Mugehu, E.; Mpofu, L. T.; Manjeru, P.

10.1101/2020.01.20.909028 — molecular biology — Posted on 2020-01-20

1580 Genomic characterization of three novel Pseudomonas phages within the subfamily of Autographivirinae isolated from organic waste

Joergensen, J. B.; Djurhuus, A. M.; Carstens, A. B.; Kot, W. P.; Morris, C. E.; Hansen, L. H.

10.1101/2020.01.20.910588 — microbiology — Posted on 2020-01-20

1581 Temperature change has the same effect as genetic variation on a morphological trait involved in reproductive isolation between Drosophila sister species

Peluffo, A. E.; Hamdani, M.; Vargas-Valderrama, A.; David, J. R.; Mallard, F.; Graner, F.; Courtier-Orgogozo, V.

10.1101/2020.01.20.911826 — evolutionary biology — Posted on 2020-01-20

1582 Characterising open chromatin identifies novel cis-regulatory elements important for paraxial mesoderm formation and axis extension

Mok, G. F.; Folkes, L.; Weldon, S.; Maniou, E.; Martinez-Heredia, V.; Godden, A.; Williams, R.; Wheeler, G. N.; Moxon, S.; Munsterberg, A.

10.1101/2020.01.20.912337 — developmental biology — Posted on 2020-01-20

1583 High Content Phenotypic Profiling in Oesophageal Adenocarcinoma Identifies Selectively Active Pharmacological Classes of Drugs for Repurposing and Chemical Starting Points for Novel Drug Discovery

Hughes, R. E.; Elliott, R. J. R.; Munro, A. F.; Makda, A.; O'Neill, J. R.; Hupp, T.; Carragher, N. O.

10.1101/2020.01.20.912212 — cancer biology — Posted on 2020-01-20

1584 Tyrosine phosphorylation of ACLY regulates lipid metabolism and oncogenesis in ALK positive Anaplastic Large Cell Lymphoma

Basappa, J.; ElAzzouny, M.; Rolland, D.; Sahasrabuddhe, A.; Ma, K.; Bazilevsky, G.; Hwang, S. R.; Basrur, V.; Conlon, K.; Bailey, N.; Frederiksen, J.; Schnell, S.; Zhou, Y.; Cookmeyer, D.; Pawlicki, J.; Amin, A. D.; Riley, J.; Faryabi, R.; Schatz, J.; Wellen, K.; Marmorstein, R.; Burant, C.; Elenitoba-Johnson, K. S.; Lim, M.

10.1101/2020.01.20.910752 — cancer biology — Posted on 2020-01-20

1585 Ethanol tolerance in Escherichia coli DH5-Alpha developed by serial exposure to sublethal doses is conferred to wild strains by horizontal gene transfer

Borana, R.; Bari, S.

10.1101/2020.01.20.912196 — microbiology — Posted on 2020-01-20

1586 The effect of statistical normalisation on network propagation scores

Picart-Armada, S.; Thompson, W. K.; Buil, A.; Perera-Lluna, A.

10.1101/2020.01.20.911842 — bioinformatics — Posted on 2020-01-20

1587 Ultrasound imaging links soleus muscle neuromechanics and energetics during human walking with elastic ankle exoskeletons

Nuckols, R. W.; Dick, T. J. M.; Beck, O. N.; Sawicki, G. S.

10.1101/2020.01.20.909259 — bioengineering — Posted on 2020-01-20

1588 Exploiting evolutionary trade-offs to combat antibiotic resistance

Melnikov, S. V.; Stevens, D. L.; Fu, X.; Kwok, H. S.; Zhang, J.-T.; Shen, Y.; Sabina, J.; Lee, K.; Lee, H.; Soll, D.

10.1101/2020.01.20.912303 — evolutionary biology — Posted on 2020-01-20

1589 Development of high-throughput screening assays for profiling snake venom Phospholipase A2 activity after high resolution chromatographic fractionation

Still, K. B.; Slagboom, J. R.; Kidwai, S.; Xie, C.; Eisses, B.; Vonk, F. J.; Somsen, G. W.; Casewell, N. R.; Kool, J.

10.1101/2020.01.20.912758 — biochemistry — Posted on 2020-01-20

1590 Loss of Tet2 affects proliferation and drug sensitivity through altered dynamics of cell-state transitions

Morinishi, L. S.; Kochanowski, K.; Levine, R.; Wu, L.; Altschuler, S.

10.1101/2020.01.20.911834 — systems biology — Posted on 2020-01-20

1591 Roq1 confers resistance to Xanthomonas, Pseudomonas syringae and Ralstonia solanacearum in tomato

Thomas, N. C.; Hendrich, C. G.; Gill, U. S.; Allen, C.; Hutton, S. F.; Schultink, A.

10.1101/813758 — plant biology — Posted on 2020-01-20

1592 Competitive Inhibition of Cortisol by Prostaglandins at the Ligand Binding Domain of Glucocorticoid Receptors

Schaper, C.

10.1101/851501 — molecular biology — Posted on 2020-01-20

1593 Genome-wide discovery of lupus genetic risk variant allelic regulatory activity

Lu, X.; Chen, X.; Forney, C.; Donmez, O.; Miller, D.; Parameswaran, S.; Hong, T.; Huang, Y.; Pujato, M.; Cazares, T.; Miraldi, E. R.; Ray, J. P.; de Boer, C. G.; Harley, J. B.; Weirauch, M. T.; Kottyan, L. C.

10.1101/2020.01.20.906701 — genomics — Posted on 2020-01-20

1594 Accurate reconstruction of the pan- and core- genomes of bacteria with PEPPA

Zhou, Z.; Achtman, M.

10.1101/2020.01.03.894154 — bioinformatics — Posted on 2020-01-20

1595 Two-way migration of Lychnis wilfordii caused by the circular landform of Japan-Korea-northeast China-Russian Far East region and its suggestion for conservation in northeast Asia

Tamura, S.; Kwak, M.-H.; Kokubugata, G.; Park, C.-h.; Lee, B.-Y.; Fukuda, T.; Petrunenko, E.; Koksheeva, I.; Pimenova, E.; Krestov, P.; Bondarchuk, S.; Ma, J.-S.; Zhou, H.-C.; Tsuboi, H.; Nishikawa, Y.; Shimamura, T.; Fujita, H.; Nakamura, K.

10.1101/857227 — evolutionary biology — Posted on 2020-01-20

1596 Quantitative method for estimating stain density in electron microscopy of conventionally prepared biological specimens

Fera, A.; He, Q.; Zhang, G.; Leapman, R. D.

10.1101/2019.12.11.873323 — biophysics — Posted on 2020-01-20

1597 Crystal and cryo-EM structures of the cytosolic G protein alpha chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1

McClelland, L. J.; Zhang, K.; Mou, T.-C.; Johnston, J.; Yates-Hansen, C.; li, S.; Thomas, C. J.; Doukov, T. I.; Triest, S.; Wohlkonig, A.; Tall, G. G.; Steyaert, J.; Chiu, W.; Sprang, S. R.

10.1101/2020.01.04.893156 — biochemistry — Posted on 2020-01-20

1598 Resident microbial communities inhibit growth and antibiotic resistance evolution of Escherichia coli in human gut microbiome samples

Baumgartner, M.; Bayer, F.; Pfrunder-Cardozo, K. R.; Buckling, A.; Hall, A. R.

10.1101/741439 — microbiology — Posted on 2020-01-20

1599 Polymorphisms in Human Cytomegalovirus gO Exert Epistatic Influences on Cell-Free and Cell-To-Cell Spread, and Antibody Neutralization on gH Epitopes.

Day, L. Z.; Stegmann, C.; Schultz, E. P.; Lanchy, J.-M.; Yu, Q.; Ryckman, B. J.

10.1101/867234 — microbiology — Posted on 2020-01-20

1600 A 19-isolate reference-quality global pangenome for the fungal wheat pathogen Zymoseptoria tritici

Badet, T.; Oggenfuss, U.; Abraham, L.; McDonald, B. A.; Croll, D.

10.1101/803098 — genomics — Posted on 2020-01-20

1601 Glycolytic mRNAs localise and are translated in Core Fermentation (CoFe) granules to fuel glucose fermentation

Morales-Polanco, F.; Bates, C.; Lui, J.; Casson, J.; Solari, C. A.; Pizzinga, M.; Forte, G.; Griffin, C.; Hubbard, S. J.; Portela, P.; Ashe, M. P.

10.1101/741231 — cell biology — Posted on 2020-01-20

1602 Trait-based approach to bacterial growth efficiency

Muscarella, M. E.; Howey, X. M.; Lennon, J. T.

10.1101/427161 — microbiology — Posted on 2020-01-20

1603 Dynamics of adaptation in an anisotropic phenotype-fitness landscape

Hamel, F.; Lavigne, F.; Martin, G.; Roques, L.

10.1101/623330 — evolutionary biology — Posted on 2020-01-20

1604 Regulation of the time when cells commit to terminally differentiate controls the number of differentiated cells

Zhao, M. L.; Rabiee, A.; Kovary, K. M.; Bahrami-Nejad, Z.; Taylor, B.; Teruel, M. N.

10.1101/632570 — cell biology — Posted on 2020-01-20

1605 High functional diversity among Nitrospira populations that dominate rotating biological contactor microbial communities in a municipal wastewater treatment plant

Spasov, E.; Tsuji, J. M.; Hug, L. A.; Doxey, A. C.; Sauder, L. A.; Parker, W. J.; Neufeld, J. D.

10.1101/529826 — microbiology — Posted on 2020-01-20

1606 S3norm: simultaneous normalization of sequencing depth and signal-to-noise ratio in epigenomic data

Xiang, G.; Keller, C.; Giardine, B.; An, L.; Li, Q.; Zhang, Y.; Hardison, R.

10.1101/506634 — bioinformatics — Posted on 2020-01-20

1607 Complete connectomic reconstruction of olfactory projection neurons in the fly brain

Bates, A. S.; Schlegel, P.; Roberts, R. J. V.; Drummond, N.; Tamimi, I. F. M.; Turnbull, R. G.; Zhao, X.; Marin, E. C.; Popovici, P. D.; Dhawan, S.; Jamasb, A. R.; Javier, A.; Li, F.; Rubin, G. M.; Waddell, S.; Bock, D. D.; Costa, M.; Jefferis, G. S. X. E.

10.1101/2020.01.19.911453 — neuroscience — Posted on 2020-01-20

1608 Heritable endogenization of an RNA virus in a mammalian species

Iida, A.; Tarigan, R.; Shimoda, H.; Endo, K.; Furuta, M.; Takemae, H.; Hayasaka, D.; Ichiyanagi, K.; Maeda, K.; Hondo, E.

10.1101/2020.01.19.911933 — genetics — Posted on 2020-01-20

1609 Ancient BED-domain-containing immune receptor from wild barley confers widely effective resistance to leaf rust

Chen, C.; Clark, B.; Martin, M. J.; Matny, O. N.; Steffenson, B. J.; Franckowiak, J. D.; Mascher, M.; Singh, D.; Perovic, D.; Richardson, T.; Periyannan, S.; Lagudah, E. S.; Park, R.; Dracatos, P. M.

10.1101/2020.01.19.911446 — plant biology — Posted on 2020-01-20

1610 Reinforcement meta-learning optimizes visuomotor learning

Sugiyama, T.; Schweighofer, N.; Izawa, J.

10.1101/2020.01.19.912048 — neuroscience — Posted on 2020-01-20

1611 A simple, cheap, and robust protocol for the identification of mating type in Saccharomyces cerevisiae

Arras, S. D. M.; Mitsugi-McHattie, L.; Woods, M. A.; Hermann-Le Denmat, S.; Ganley, A. R. D.

10.1101/2020.01.19.911990 — microbiology — Posted on 2020-01-20

1612 T cell responses induced by attenuated flavivirus vaccination are specific and show limited cross-reactivity with other flavivirus species.

Grifoni, A.; Voic, H.; Dhanda, S. K.; Kidd, C. K.; Brien, J. D.; Buus, S.; Stryhn, A.; Durbin, A. P.; Whitehead, S.; Diehl, S. A.; de Silva, A. D.; Balmaseda, A.; Harris, E.; Weiskopf, D.; Sette, A.

10.1101/2020.01.17.911099 — immunology — Posted on 2020-01-20

1613 Strategies for cellular deconvolution in human brain RNA sequencing data

Sosina, O. A.; Tran, M. N.; Maynard, K.; Tao, R.; Taub, M. A.; Martinowich, K.; Semick, S. A.; Weinberger, D.; Quach, B. C.; Hyde, T. M.; Hancock, D. B.; Kleinman, J. E.; Leek, J. T.; Jaffe, A. E.

10.1101/2020.01.19.910976 — genomics — Posted on 2020-01-20

1614 Neutralizing PD-L1 and PD-L2 Enhances the Efficacy of Immune Checkpoint Inhibitors in Ovarian Cancer.

Miao, Y. R.; Thakkar, K. N.; Qian, J.; Kariolis, M. S.; Huang, W.; Nandagopal, S. A.; Yang, T.; Diep, A. N.; Cherf, G. M.; Xu, Y.; Moon, E. J.; Xiao, Y.; Alemany, H.; Li, T.; Yu, W.; Wei, B.; Rankin, E. B.; Giaccia, A. J.

10.1101/2020.01.19.911941 — cancer biology — Posted on 2020-01-20

1615 MQ: Tool for HR-AM Based Quantitative Analysis for Direct MS Workflow

Ghanate, A.; Parmar, D.; Bhattacharya, N.; Inamdar, I.; Phadke, G.; Panchagnula, V.

10.1101/2020.01.19.912055 — bioinformatics — Posted on 2020-01-20

1616 Three genomes of Osteoglossidae shed light on ancient teleost evolution

Hao, S.; Han, K.; Meng, L.; Huang, X.; Shi, C.; Zhang, M.; Wang, Y.; Liu, Q.; Zhang, Y.; Seim, I.; Xu, X.; Liu, X.; Fan, G.

10.1101/2020.01.19.911958 — genomics — Posted on 2020-01-20

1617 Compartmentalization of enhanced biomolecular interactions for high-throughput drug screening in test tubes

Zhou, M.; Li, W.; Li, J.; Xie, L.; Wu, R.; Wang, L.; Fu, S.; Su, W.; Hu, J.; Wang, J.; Li, P.

10.1101/2020.01.19.911149 — biophysics — Posted on 2020-01-20

1618 New plasmon-polariton model of the saltatory conduction

Jacak, W. A.

10.1101/2020.01.17.910596 — neuroscience — Posted on 2020-01-20

1619 Phosphorylation Dependent Assembly of a 14-3-3 Mediated Signaling Complex During Red Blood Cell Invasion by Plasmodium falciparum Merozoites

More, K. R.; Kaur, I.; Giai Gianetto, Q.; Invergo, B. M.; Chaze, T.; Jain, R.; Huon, C.; Gutenbrunner, P.; Weisser, H.; Matondo, M.; Chaudhary, J. S.; Langsley, G.; Singh, S.; Chitnis, C. E.

10.1101/2020.01.17.911107 — microbiology — Posted on 2020-01-20

1620 Phages actively challenge niche communities in the Antarctic soils

Bezuidt, O. K. I.; Lebre, P. H.; Pierneef, R.; Leon-Sobrino, C.; Adriaenssens, E. M.; Cowan, D. A.; Van de Peer, Y.; Makhalanyane, T. P.

10.1101/2020.01.17.911081 — microbiology — Posted on 2020-01-20

1621 Dissecting endothelial to haematopoietic stem cell transition by single-cell transcriptomic and functional analyses

Hou, S.; Li, Z.; Zheng, X.; Gao, Y.; Dong, J.; Ni, Y.; Wang, X.; Li, Y.; Ding, X.; Chang, Z.; Li, S.; Hu, Y.; Fan, X.; Hou, Y.; Wen, L.; Liu, B.; Tang, F.; Lan, Y.

10.1101/2020.01.18.910356 — developmental biology — Posted on 2020-01-20

1622 Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response

Sun, K. A.; Li, Y.; Meliton, A. Y.; Woods, P. S.; Kimmig, L. M.; Hamanaka, R. B.; Mutlu, G.

10.1101/2020.01.19.911917 — cell biology — Posted on 2020-01-20

1623 Computational estimates of mechanical constraints on cell migration through extracellular matrix

Maxian, O.; Mogilner, A.; Strychalski, W.

10.1101/2020.01.19.912006 — cell biology — Posted on 2020-01-20

1624 Human AKTIP interacts with ESCRT proteins and functions at the midbody in cytokinesis

Merigliano, C.; Burla, R.; La Torre, M.; Del Giudice, S.; Teo, H. L.; Liew, C. W.; Goh, W. I.; Chojnowski, A.; Olmos, Y.; Chiolo, I. E.; Carlton, J. G.; Raimondo, D.; Stewart, C. L.; Rhodes, D.; Wright, G. D.; Burke, B.; Saggio, I.

10.1101/2020.01.19.911891 — cell biology — Posted on 2020-01-20

1625 Automated screening by 3D light-sheet microscopy with high spatial and temporal resolution reveals mitotic phenotypes

Eismann, B.; Krieger, T. G.; Beneke, J.; Bulkescher, R.; Adam, L.; Erfle, H.; Herrmann, C.; Eils, R.; Conrad, C.

10.1101/2020.01.20.912659 — cell biology — Posted on 2020-01-20

1626 Mechanical-control of cell proliferation increases resistance to chemotherapeutic agents

Rizzuti, I.; Mascheroni, P.; Arcucci, S.; Ben-Meriem, Z.; Prunet, A.; Barentin, C.; Riviere, C.; Delanoe-Ayari, H.; Hatzikirou, H.; Guillermet-Guibert, J.; Delarue, M.

10.1101/2020.01.18.910554 — cancer biology — Posted on 2020-01-20

1627 LTD at amygdalocortical synapses as a novel mechanism for hedonic learning

Haley, M. S.; Bruno, S.; Fontanini, A.; Maffei, A.

10.1101/753590 — neuroscience — Posted on 2020-01-20

1628 Altered directed functional connectivity of the right amygdala in depression: high-density EEG study

Damborska, A.; Honzirkova, E.; Bartecek, R.; Horinkova, J.; Fedorova, S.; Ondrus, S.; Michel, C.; Rubega, M.

10.1101/620252 — neuroscience — Posted on 2020-01-20

1629 Sub-species niche specialization in the oral microbiome is associated with nasopharyngeal carcinoma risk

Debelius, J. W.; Huang, T.; Cai, Y.; Ploner, A.; Barrett, D.; Zhou, X.; Xiao, X.; Li, Y.; Liao, J.; Zheng, Y.; Huang, G.; Adami, H.-O.; Zeng, Y.; Zhang, Z.; Ye, W.

10.1101/782417 — microbiology — Posted on 2020-01-20

1630 Stoichiometric constraints modulate the effects of temperature and nutrients on biomass distribution and community stability

Sentis, A.; Haegeman, B.; Montoya, J. M.

10.1101/589895 — ecology — Posted on 2020-01-20

1631 Super-Beacons: open-source probes with spontaneous tunable blinking compatible with live-cell super-resolution microscopy

Pereira, P. M.; Gustafsson, N.; Marsh, M.; Mhlanga, M. M.; Henriques, R.

10.1101/2020.01.20.912311 — cell biology — Posted on 2020-01-20

1632 Super-resolution visualization of distinct stalled and broken replication fork structures

Whelan, D. R.; Lee, W. T. C.; Marks, F.; Kong, Y. T.; Yin, Y.; Rothenberg, E.

10.1101/2020.01.19.912014 — genomics — Posted on 2020-01-20

1633 NeuroPycon: An open-source Python toolbox for fast multi-modal and reproducible brain connectivity pipelines

Meunier, D.; Pascarella, A.; Altukhov, D.; Jas, M.; Combrisson, E.; Lajnef, T.; Bertrand-Dubois, D.; Hadid, V.; Alamian, G.; Alves, J.; Barlaam, F.; Saive, A.-L.; Dehgan, A.; Jerbi, K.

10.1101/789842 — neuroscience — Posted on 2020-01-20

1634 An African origin for Mycobacterium bovis

Loiseau, C. M.; Menardo, F.; Aseffa, A.; Hailu, E.; Gumi, B.; Ameni, G.; Berg, S.; Rigouts, L.; Robbe-Austerman, S.; Zinsstag, J.; Gagneux, S.; Brites, D.

10.1101/773192 — evolutionary biology — Posted on 2020-01-20

1635 Limited phenological and pollinator-mediated isolation among selfing and outcrossing Arabidopsis lyrata populations

Gorman, C.; Bond, L.; van Kleunen, M.; Dorken, M.; Stift, M.

10.1101/2019.12.17.879361 — ecology — Posted on 2020-01-20

1636 Diapause is not selected as a bet-hedging strategy in insects: a meta-analysis of reaction norm shapes

Joschinski, J.; Bonte, D.

10.1101/752881 — ecology — Posted on 2020-01-20

1637 Inter-subject phase synchronization differentiates neural networks underlying physical pain empathy

Xu, L.; Bolt, T. S.; Nomi, J.; Li, J.; Zheng, X.; Fu, M.; Kendrick, K. M.; Becker, B.; Uddin, L. Q.

10.1101/841197 — neuroscience — Posted on 2020-01-20

1638 Embedding the Skin Conductance Response into the Brain Connectivity Framework: Monoaminergic Signaling Visible Through the Lenses of Computational Modeling

Brankovic, S.

10.1101/504183 — neuroscience — Posted on 2020-01-20

1639 Primordial emergence of a nucleic acid binding protein via phase separation and statistical ornithine to arginine conversion

Longo, L. M.; Despotovic, D.; Weil-Ktorza, O.; Walker, M. J.; Jablonska, J.; Fridmann-Sirkis, Y.; Varani, G.; Metanis, N.; Tawfik, D. S.

10.1101/2020.01.18.911073 — biochemistry — Posted on 2020-01-20

1640 On the cortical mapping function -- visual space, cortical space, and crowding

Strasburger, H.

10.1101/621458 — neuroscience — Posted on 2020-01-20

1641 Calcium-independent astrocytic lipid release modulates neuronal activity through Kv channels

Wang, F.; Bradshaw, H. B.; Jablonska, B.; Pena, S. E.; Xavier, J.; Gong, S.; Li, B.; Chandler-Militello, D.; Bekar, L. K.; Smith, N. A.

10.1101/2020.01.12.903393 — neuroscience — Posted on 2020-01-20

1642 Zygomorphic flowers have fewer visitors

Yoder, J. B.; Gomez, G.; Carlson, C. J.

10.1101/743872 — ecology — Posted on 2020-01-20

1643 Local retinoic acid directs emergence of the extraocular muscle functional unit

Comai, G. E.; Tesarova, M.; Dupe, V.; Rhinn, M.; Vallecillo Garcia, P.; da Silva, F.; Feret, B.; Exelby, K.; Dolle, P.; Carlsson, L.; Pryce, B.; Spitz, F.; Stricker, S.; Zikmund, T.; Kaiser, J.; Briscoe, J.; Schedl, A.; Ghyselinck, N. B.; Schweitzer, R.; Tajbakhsh, S.

10.1101/2020.01.07.897694 — developmental biology — Posted on 2020-01-20

1644 Deciphering the regulatory genome of Escherichiacoli, one hundred promoters at a time

Ireland, W. T. T.; Beeler, S. M.; Flores-Bautista, E.; Belliveau, N. M.; Sweredoski, M. J.; Moradian, A.; Kinney, J. B.; Phillips, R.

10.1101/2020.01.18.910323 — biophysics — Posted on 2020-01-20

1645 Estimating the quality of eukaryotic genomes recovered from metagenomic analysis

Saary, P.; Mitchell, A. L.; Finn, R. D.

10.1101/2019.12.19.882753 — bioinformatics — Posted on 2020-01-20

1646 CSF1R inhibition by a small molecule inhibitor affects hematopoiesis and the function of macrophages.

Lei, F.; Cui, N.; Zhou, C.; Chodosh, J.; Vavvas, D. G.; Paschalis, E. I.

10.1101/2019.12.27.889469 — neuroscience — Posted on 2020-01-20

1647 A Bayesian Multi-Task Approach for Detecting Global Microbiome Associations

Hatami, F.; Beamish, E.; Rigby, R.; Dondelinger, F.

10.1101/2020.01.08.897538 — microbiology — Posted on 2020-01-20

1648 Rats Sniff Off Toxic Air

Chen, H.; Li, X.; Yao, M.

10.1101/739003 — biochemistry — Posted on 2020-01-20

1649 RESILIENCE TO COGNITIVE AGING IS ASSOCIATED WITH RESPONSIVENESS OF DENTATE NEURONS GENERATED THROUGHOUT ADULT LIFE

Montaron, M.-F.; CHARRIER, V.; Blin, N.; Garcia, P.; Abrous, D. N.

10.1101/290676 — neuroscience — Posted on 2020-01-20

1650 Activation of cryptic splicing in bovine WDR19 is associated with reduced semen quality and male fertility

Hiltpold, M.; Niu, G.; Kadri, N. K.; Crysnanto, D.; Fang, Z.-H.; Spengeler, M.; Schmitz-Hsu, F.; Fuerst, C.; Schwarzenbacher, H.; Seefried, F. R.; Seehusen, F.; Schnieke, A.; Fries, R.; Bollwein, H.; Flisikowski, K.; Pausch, H.

10.1101/2020.01.16.907865 — genomics — Posted on 2020-01-20

1651 Surveying Brain Tumor Heterogeneity by Single-Cell RNA Sequencing of Multi-sector Biopsies

Yu, K.; Hu, Y.; Wu, F.; Guo, Q.; Qian, Z.; Hu, W.; Chen, J.; Wang, K.; Fan, X.; Wu, X.; Rasko, J. E.; Fan, X.; Iavarone, A.; Jiang, T.; Tang, F.; Su, X.-D.

10.1101/2020.01.19.911701 — genomics — Posted on 2020-01-19

1652 Connecting secretome to hematopoietic stem cell phenotype shifts in an engineered bone marrow niche

Gilchrist, A. E.; Harley, B.

10.1101/2020.01.19.911800 — bioengineering — Posted on 2020-01-19

1653 Design of a biosensor for direct visualisation of auxin

Herud-Sikimic, O.; Stiel, A. C.; Ortega-Perez, M.; Shanmugaratnam, S.; Hoecker, B.; Juergens, G. C.

10.1101/2020.01.19.911735 — plant biology — Posted on 2020-01-19

1654 DNA damage and macrophage infiltration in the ovaries of the long-lived GH deficient Ames Dwarf and the short-lived bGH transgenic mice

Saccon, T. D.; Rovani, M.; Garcia, D.; Pradiee, J.; Mondadori, R.; Cruz, L.; Barros, C.; Fang, Y.; McFaden, S.; Bartke, A.; masternak, M.; Schneider, A.

10.1101/2020.01.19.911677 — physiology — Posted on 2020-01-19

1655 A role for the Fem-1 gene of Drosophila melanogaster in adult courtship

Thies, M.; Berke, B.

10.1101/2020.01.19.911693 — neuroscience — Posted on 2020-01-19

1656 Three major dimensions of human brain cortical ageing in relation to cognitive decline across the 8th decade of life.

Cox, S. R.; Harris, M. A.; Ritchie, S. J.; Buchanan, C. R.; Valdes Hernandez, M. d. C.; Corley, J.; Taylor, A. M.; Madole, J. W.; Harris, S. E.; Whalley, H. C.; McIntosh, A. M.; Russ, T. C.; Bastin, M. E.; Wardlaw, J. M.; Deary, I. J.; Tucker-Drob, E. M.

10.1101/2020.01.19.911420 — neuroscience — Posted on 2020-01-19

1657 Cerebello-Thalamic Spike Transfer via Temporal Coding and Cortical Adaptation

Schafer, C. B.; Gao, Z.; De Zeeuw, C. I.; Hoebeek, F. E.

10.1101/2020.01.19.911610 — neuroscience — Posted on 2020-01-19

1658 A Refined View of Airway Microbiome in Chronic Obstructive Pulmonary Disease at Species and Strain-levels

Wang, Z.; Liu, H.; Wang, F.; Yang, Y.; Wang, X.; Chen, B.; Stampfli, M.; Zhou, H.; Shu, W.; Brightling, C.; Liang, Z.; Chen, R.

10.1101/2020.01.18.908624 — microbiology — Posted on 2020-01-19

1659 Exploring the remarkable diversity of Escherichia coli Phages in the Danish Wastewater Environment, Including 91 Novel Phage Species

Olsen, N. S.; Kot, W.; Junco, L. M. F.; Hansen, L. H.

10.1101/2020.01.19.911818 — microbiology — Posted on 2020-01-19

1660 Modeling SIV kinetics supports that cytotoxic response drives natural control and unravels heterogeneous populations of infected cells

Madelain, V.; Passaes, C.; Millet, A.; Avettand-Fenoel, V.; Djidjou-Demasse, R.; Dereuddre-Bosquet, N.; Le Grand, R.; Rouzioux, C.; Vaslin, B.; Saez-Cirion, A.; Guedj, J.

10.1101/2020.01.19.911594 — microbiology — Posted on 2020-01-19

1661 Intratumor Heterogeneity and Evolution of Colorectal Cancer

Banerjee, S.; Zhang, X.; Kuang, S.; Wang, J.; Li, L.; Fan, G.; Luo, Y.; Sun, S.; Han, P.; Wu, Q.; Yang, S.; Ji, X.; Li, Y.; Deng, L.; Tian, X.; Wang, Z.; Zhang, Y.; Wu, K.; Zhu, S.; Hodgson, S. V.; Brahmachari, S.; Bolund, L.; Yang, H.; Xu, X.; Liu, J.; Lu, Y.; Liu, X.

10.1101/2020.01.13.904276 — genetics — Posted on 2020-01-19

1662 On the origin and evolution of RNA editing in metazoans

Li, Q.; Zhang, P.; Li, J.; Yu, H.; Zhan, X.; Zhu, Y.; Guo, Q.; Tan, H.; Lundholm, N.; Garcia, L.; Martin, M. D.; Subirats, M. A.; Su, Y.-H.; Ruiz-Trillo, I.; Martindale, M. Q.; Yu, J.-K.; Gilbert, M. T. P.; Zhang, G.

10.1101/2020.01.19.911685 — evolutionary biology — Posted on 2020-01-19

1663 Anisotropic mineralized collagen scaffolds accelerate osteogenic response in a glycosaminoglycan-dependent fashion

Dewey, M. J.; Nosatov, A. V.; Subedi, K.; Harley, B.

10.1101/2020.01.19.911305 — bioengineering — Posted on 2020-01-19

1664 Set-size effects in change detection depend on failures of retrieval and/or comparison and not on perception, encoding or storage

Moreland, J. C.; Palmer, J.; Boynton, G. M.

10.1101/2020.01.19.911867 — animal behavior and cognition — Posted on 2020-01-19

1665 Cross-Cancer Evaluation of Polygenic Risk Scores for 17 Cancer Types in Two Large Cohorts

Graff, R. E.; Cavazos, T. B.; Thai, K. K.; Kachuri, L. E.; Rashkin, S. R.; Hoffman, J. D.; Alexeeff, S. E.; Blatchins, M.; Meyers, T. J.; Leong, L.; Tai, C. G.; Emami, N. C.; Corley, D. A.; Kushi, L. H.; Ziv, E.; Van Den Eeden, S. K.; Jorgenson, E.; Hoffmann, T. J.; Habel, L. A.; Witte, J. S.; Sakoda, L. C.

10.1101/2020.01.18.911578 — genetics — Posted on 2020-01-19

1666 NetMix: A network-structured mixture model for reduced-bias estimation of altered subnetworks

Reyna, M. A.; Chitra, U.; Elyanow, R.; Raphael, B. J.

10.1101/2020.01.18.911438 — bioinformatics — Posted on 2020-01-19

1667 Potential short-term earthquake forecasting by farm-animal monitoring

Wikelski, M.; Mueller, U.; Scocco, P.; Catorci, A.; Desinov, L. V.; Belyaev, M.; Keim, D. A.; Pohlmeier, W.; Fechteler, G.; Mai, P. M.

10.1101/2020.01.19.911313 — animal behavior and cognition — Posted on 2020-01-19

1668 Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Huttlin, E. L.; Bruckner, R. J.; Navarrete-Perea, J.; Cannon, J. R.; Baltier, K.; Gebreab, F.; Gygi, M. P.; Thornock, A.; Zarraga, G.; Tam, S.; Szpyt, J.; Panov, A.; Parzen, H.; Fu, S.; Golbazi, A.; Maenpaa, E.; Stricker, K.; Guha Thakurta, S.; Rad, R.; Pan, J.; Nusinow, D. P.; Paulo, J. A.; Schweppe, D. K.; Pontano Vaites, L.; Harper, W.; Gygi, S.

10.1101/2020.01.19.905109 — systems biology — Posted on 2020-01-19

1669 A mathematical model for simulating the transmission of Wuhan novel Coronavirus

Chen, T.; Rui, J.; Wang, Q.; Zhao, Z.; Cui, J.-A.; Yin, L.

10.1101/2020.01.19.911669 — systems biology — Posted on 2020-01-19

1670 Multi-faceted deregulation of gene expression and protein synthesis with age

Anisimova, A. S.; Meerson, M. B.; Gerashchenko, M.; Kulakovskiy, I. V.; Dmitriev, S. E.; Gladyshev, V. N.

10.1101/2020.01.19.911404 — systems biology — Posted on 2020-01-19

1671 AAV Ablates Neurogenesis in the Adult Murine Hippocampus

Johnston, S. T.; Parylak, S. L.; Kim, S.; Mac, N.; Lim, C.; Gallina, I.; Bloyd, C.; Newberry, A.; Saavedra, C.; Novák, O.; Goncalves, J. T.; Gage, F. H.; Shtrahman, M.

10.1101/2020.01.18.911362 — neuroscience — Posted on 2020-01-19

1672 The Requirement For US28 During Cytomegalovirus Latency Is Independent Of US27 And US29 Gene Expression

Krishna, B. A.; Wass, A. B.; Sridharan, R.; O'Connor, C. M.

10.1101/2020.01.19.911503 — microbiology — Posted on 2020-01-19

1673 BREM-SC: A Bayesian Random Effects Mixture Model for Joint Clustering Single Cell Multi-omics Data

Wang, X.; Sun, Z.; Zhang, Y.; Xu, Z.; Huang, H.; Duerr, R. H.; Chen, K.; Ding, Y.; Chen, W.

10.1101/2020.01.18.911461 — genomics — Posted on 2020-01-19

1674 Registration-free Distortion Correction of Diffusion Weighted MRI

Schilling, K. G.; Blaber, J.; Hansen, C.; Rogers, B.; Anderson, A. W.; Smith, S.; Kanakaraj, P.; Rex, T.; Resnick, S. M.; Shafer, A. T.; Cutting, L.; Woodward, N.; Zald, D.; Landman, B. A.

10.1101/2020.01.19.911784 — bioengineering — Posted on 2020-01-19

1675 Integration of New Information in Memory: New Insights from a Complementary Learning Systems Perspective

McClelland, J. L.; McNaughton, B. L.; Lampinen, A. K.

10.1101/2020.01.17.909804 — neuroscience — Posted on 2020-01-19

1676 Diagnostic of begomoviruses in complex infections -a case study

Jovel, J.

10.1101/2020.01.19.911776 — molecular biology — Posted on 2020-01-19

1677 Systematic revision and redefinition of the genus Scirrotherium Edmund and Theodor, 1997 (Cingulata, Pampatheriidae): Implications for the origin of pampatheriids and the evolution of the South American lineage including Holmesina

Jimenez-Lara, K.

10.1101/719153 — paleontology — Posted on 2020-01-19

1678 Different principles govern different scales of brain folding

Mallela, A. N.; Deng, H.; Bush, A.; Goldschmidt, E.

10.1101/851550 — neuroscience — Posted on 2020-01-19

1679 Harmonic-Balance Circuit Analysis for Electro-Neural Interfaces

Chen, Z. C.; Wang, B.; Palanker, D.

10.1101/2020.01.17.910968 — bioengineering — Posted on 2020-01-19

1680 Visuo-proprioceptive control of the hand in older adults

Block, H. J.; Sexton, B. M.

10.1101/2020.01.18.911354 — neuroscience — Posted on 2020-01-19

1681 Neuronal firing and waveform alterations through ictal recruitment in humans

Merricks, E. M.; Smith, E. H.; Emerson, R. G.; Bateman, L. M.; McKhann, G. M.; Goodman, R. R.; Sheth, S. A.; Greger, B.; House, P. A.; Trevelyan, A. J.; Schevon, C. A.

10.1101/2020.01.11.902817 — neuroscience — Posted on 2020-01-19

1682 Splicing of the SynGAP Carboxyl-Terminus Enables Isoform-Specific Tuning of NMDA Receptor Signaling Linked to Cognitive Function

Kilinc, M.; Creson, T. K.; Rojas, C.; Maity, S.; Le, A. A.; Lauterborn, J.; Wilkinson, B.; Hartel, N.; Graham, N. A.; Reich, A.; Gou, G.; Araki, Y.; Bayes, A.; Coba, M. P.; Lynch, G.; Miller, C. A.; Rumbaugh, G.

10.1101/2020.01.18.911487 — neuroscience — Posted on 2020-01-19

1683 Proteome specialization of anaerobic fungi during ruminal degradation of recalcitrant plant fiber

Hagen, L. H.; Brooke, C. G.; Shaw, C.; Norbeck, A. D.; Piao, H.; Arntzen, M. O.; Brewer, H.; Copeland, A.; Isern, N.; Shukla, A.; Roux, S.; Lombard, V.; Henrissat, B.; O'Malley, M.; Grigoriev, I. V.; Tringe, S.; Mackie, R.; Pasa-Tolic, L.; Pope, P. B.; Hess, M.

10.1101/2020.01.16.907998 — microbiology — Posted on 2020-01-19

1684 Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers

Cohen, A. A.; Yang, Z.; Gnanapragasam, P.; Ou, S.; Dam, K.-M.; Wang, H.; Bjorkman, P. J.

10.1101/2020.01.18.911388 — immunology — Posted on 2020-01-19

1685 Nuclear Plasticity Increases Susceptibility to Damage During Confined Migration

Mukherjee, A.; Barai, A.; Singh, R.; Yan, W.; Sen, S.

10.1101/2020.01.18.911529 — biophysics — Posted on 2020-01-19

1686 ETHYLENE RESPONSE FACTOR 115 integrates jasmonate and cytokinin signaling machineries to repress adventitious rooting in Arabidopsis

Lakehal, A.; Dob, A.; Rahneshan, Z.; Novak, O.; Escamez, S.; Alallaq, S.; Strnad, M.; Tuominen, H.; Bellini, C.

10.1101/2019.12.27.886796 — plant biology — Posted on 2020-01-19

1687 The neuroanatomical ultrastructure and function of a biological ring attractor

Turner-Evans, D. B.; Jensen, K.; Ali, S.; Paterson, T.; Sheridan, A.; Ray, R. P.; Wolff, T.; Lauritzen, S.; Rubin, G. M.; Bock, D.; Jayaraman, V.

10.1101/847152 — neuroscience — Posted on 2020-01-19

1688 The uptake of tau amyloid fibrils is facilitated by the cellular prion protein and hampers prion propagation in cultured cells

De Cecco, E.; Celauro, L.; Vanni, S.; Grandolfo, M.; Aguzzi, A.; Legname, G.

10.1101/2020.01.19.911644 — neuroscience — Posted on 2020-01-19

1689 Murine Staphylococcus aureus chronic infection is cured by theory-driven therapy

Papaxenopoulou, L. A.; Zao, G.; Khailaie, S.; Katsoulis-Dimitriou, K.; Schmitz, I.; Medina, E.; Hatzikirou, H.; Meyer-Hermann, M.

10.1101/2020.01.17.910786 — systems biology — Posted on 2020-01-19

1690 A possible coding for experience: ripple-like events and synaptic diversity

Ishikawa, J.; Tomokage, T.; Mitsushima, D.

10.1101/2019.12.30.891259 — animal behavior and cognition — Posted on 2020-01-19

1691 Dual stochasticity in the cortex as a biologically plausible learning with the most efficient coding

Teramae, J.-n.

10.1101/811646 — neuroscience — Posted on 2020-01-19

1692 Delta phase resets mediate non-rhythmic temporal prediction

Daume, J.; Wang, P.; Maye, A.; Zhang, D.; Engel, A. K.

10.1101/643957 — neuroscience — Posted on 2020-01-19

1693 Completion and augmentation of connectomic datasets in dementia and Alzheimer's Disease using Virtual Patient Cohorts

Arbabyazd, D. M.; Shen, K.; Wang, Z.; Hofman-Apitius, M.; McIntosh, A. R.; Battaglia, D.; Jirsa, V.

10.1101/2020.01.18.911248 — neuroscience — Posted on 2020-01-19

1694 Prediction of specific TCR-peptide binding from large dictionaries of TCR-peptide pairs

Springer, I.; Besser, H.; Tickotsky-Moskovitz, N.; Dvorkin, S.; Louzoun, Y.

10.1101/650861 — immunology — Posted on 2020-01-19

1695 In-silico immune cell deconvolution of the airway proteomes of infants with pneumonia reveals a link between reduced airway eosinophils and an increased risk of mortality

Sande, C. J.; Waeni, J. M.; Njunge, J. M.; Mutunga, M. M.; Gicheru, E. T.; Kibinge, N. K.; Gwela, A.

10.1101/840090 — immunology — Posted on 2020-01-19

1696 Multiplex genetic engineering exploiting pyrimidine salvage pathway-based self-encoded selectable markers

Birstonas, L.; Dallemulle, A.; Lopez-Berges, M. S.; Jacobsen, I. D.; Offterdinger, M.; Abt, B.; Strassburger, M.; Bauer, I.; Schmidt, O.; Sarg, B.; Lindner, H.; Haas, H.; Gsaller, F.

10.1101/2020.01.16.908764 — genetics — Posted on 2020-01-19

1697 A standardized and reproducible method to measure decision-making in mice

The International Brain Laboratory, ; Aguillon, V.; Angelaki, D.; Bayer, H. M.; Bonacchi, N.; Carandini, M.; Cazettes, F.; Churchland, A. K.; Chapuis, G.; Dan, Y.; Dewitt, E.; Faulkner, M.; Hamish, F.; Haetzel, L.; Hausser, M.; Hofer, S.; Hu, F.; Khanal, A.; Krasniak, C.; Laranjeira, I.; Mainen, Z.; Meijer, G.; Miska, N.; Mrsic-Flogel, T.; Noel, J.-P.; Pan Vazquez, A.; Sanders, J.; Socha, K.; Terry, R.; Urai, A.; Vergara, H. M.; Wells, M.; Wilson, C.; Witten, I.; Wool, L.; Zador, A.

10.1101/2020.01.17.909838 — neuroscience — Posted on 2020-01-19

1698 Elucidating the complex organization of neural micro-domains in the locust Schistocerca gregaria using dMRI

Shahid, S. S.; Kerskens, C. M.; Burrows, M.; Witney, A. G.

10.1101/2020.01.17.910851 — neuroscience — Posted on 2020-01-19

1699 Advances in Spiral fMRI: A High-resolution Study with Single-shot Acquisition

Kasper, L.; Engel, M.; Heinzle, J.; Mueller-Schrader, M.; Graedel, N. N.; Reber, J.; Schmid, T.; Barmet, C.; Wilm, B. J.; Stephan, K. E.; Pruessmann, K. P.

10.1101/842179 — neuroscience — Posted on 2020-01-19

1700 Amelioration of Brain Histone Methylopathies by Balancing a Writer-Eraser Duo KMT2A-KDM5C

Vallianatos, C. N.; Raines, B.; Porter, R. S.; Bonefas, K. M.; Wu, M. C.; Garay, P. M.; Collette, K. M.; Seo, Y. A.; Dou, Y.; Keegan, C. E.; Tronson, N.; Iwase, S.

10.1101/567917 — genetics — Posted on 2020-01-19

1701 Intramembrane protease RHBDL4 cleaves oligosaccharyltransferase subunits to target them for ER-associated degradation

Knopf, J. D.; Landscheidt, N.; Pegg, C. L.; Schulz, B. L.; Kuehnle, N.; Chao, C.-W.; Huck, S.; Lemberg, M. K.

10.1101/850776 — cell biology — Posted on 2020-01-19

1702 Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation

Fang, C.; Wang, Z.; Han, C.; Safgren, S. L.; Helmin, K. A.; Adelman, E. R.; Eagen, K. P.; Gaspar-Maia, A.; Figueroa, M. E.; Singer, B. D.; Ratan, A.; Ntziachristos, P.; Zang, C.

10.1101/2020.01.17.910687 — genomics — Posted on 2020-01-18

1703 Hydroxyl carlactone derivatives are predominant strigolactones in Arabidopsis

Yoneyama, K.; Akiyama, K.; Brewer, P.; Mori, N.; Kawano-Kawada, M.; Haruta, S.; Nishiwaki, H.; Yamauchi, S.; Xie, X.; Umehara, M.; Beveridge, C. A.; Yoneyama, K.; Nomura, T.

10.1101/2020.01.17.910877 — plant biology — Posted on 2020-01-18

1704 A role for reward sensitivity in the serotonergic modulation of impulsivity

Desrochers, S. S.; Lesko, E. K.; Magalong, V. M.; Balsam, P. D.; Nautiyal, K. M.

10.1101/2020.01.17.910778 — neuroscience — Posted on 2020-01-18

1705 Selective Postnatal Excitation of Neocortical Pyramidal Neurons Results in Distinctive Behavioral and Circuit Deficits in Adulthood

Medendorp, W. E.; Pal, A.; Waddell, M. L.; Bjorefeldt, A.; Moore, C. I.; Hochgeschwender, U.

10.1101/2020.01.18.911347 — neuroscience — Posted on 2020-01-18

1706 Limiting Self-Renewal of the Basal Compartment Induces Differentiation and Alters Evolution of Mammary Tumors

Ognjenovic, N. B.; Bagheri, M.; Mohamed, G. A.; Xu, K.; Brown, M. S.; Chen, Y.; Mohamed Saleem, M. A.; Nagaraj, S. H.; Muller, K. E.; Christensen, B.; Pattabiraman, D. R.

10.1101/2020.01.18.907741 — cancer biology — Posted on 2020-01-18

1707 Network Insights into Improving Drug Target Inference Algorithms

Wang, M.; Noh, H.; Mochan, E.; Shoemaker, J. E.

10.1101/2020.01.17.910885 — systems biology — Posted on 2020-01-18

1708 A Simultaneous Methylome and Proteome Quantitative Workflow for Complex Samples

Robinson, A. E.; Binek, A.; Holewinski, R.; Venkatraman, V.; Parker, S. J.; Basisty, N.; Xie, X.; Lund, P. J.; Saxena, G.; Mato, J. M.; Garcia, B. A.; Schilling, B.; Lu, S. C.; Van Eyk, J. E.

10.1101/2020.01.17.910943 — systems biology — Posted on 2020-01-18

1709 ER-Anchored Transcription Factors bZIP17 and bZIP60 Regulate Triterpene Saponin Biosynthesis in Medicago truncatula

Ribeiro, B.; Erffelinck, M.-L.; Colinas, M.; Williams, C. J.; Van Hamme, E.; Lacchini, E.; De Clercq, R.; Perassolo, M.; Goossens, A.

10.1101/2020.01.17.910802 — plant biology — Posted on 2020-01-18

1710 Visuo-proprioceptive control of the hand in older adults

Block, H. J.; Sexton, B. M.

10.1101/2020.01.18.911354 — neuroscience — Posted on 2020-01-18

1711 Multidimensional hydrogel models reveal endothelial network angiocrine signals increase glioblastoma proliferation, invasion, and temozolomide resistance

Ngo, M. T.; Karvelis, E.; Harley, B.

10.1101/2020.01.18.911396 — bioengineering — Posted on 2020-01-18

1712 Skd3 (human CLPB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations

Cupo, R. R.; Shorter, J.

10.1101/2020.01.17.911016 — biochemistry — Posted on 2020-01-18

1713 Finding new cancer epigenetic and genetic biomarkers from cell-free DNA by combining SALP-seq and machine learning：esophageal cancer as an example

Liu, S.; Wu, J.; Xia, Q.; Liu, H.; Li, W.; Xia, X.; Wang, J.

10.1101/2020.01.18.911172 — cancer biology — Posted on 2020-01-18

1714 High-Throughput Functional Evaluation of BRCA2 Variants of Unknown Significance

Ikegami, M.; Kohsaka, S.; Ueno, T.; Momozawa, Y.; Tamura, K.; Shimomura, A.; Hosoya, N.; Kobayashi, H.; Tanaka, S.; Mano, H.

10.1101/2020.01.17.911057 — cancer biology — Posted on 2020-01-18

1715 Multimodal magnetic resonance imaging predicts regional amyloid-β burden in the brain

Alathur Rangarajan, A.; Wu, M.; Joseph, N.; Karim, H.; Laymon, C.; Tudorascu, D.; Cohen, A.; Klunk, W.; Aizenstein, H.

10.1101/2020.01.17.910984 — bioengineering — Posted on 2020-01-18

1716 Completion and augmentation of connectomic datasets in dementia and Alzheimer's Disease using Virtual Patient Cohorts

Arbabyazd, D. M.; Shen, K.; Wang, Z.; Hofman-Apitius, M.; McIntosh, A. R.; Battaglia, D.; Jirsa, V.

10.1101/2020.01.18.911248 — neuroscience — Posted on 2020-01-18

1717 Kctd15 regulates nephron segment development by repressing Tfap2a activity

Chambers, B. E.; Clark, E. G.; Gatz, A. E.; Wingert, R. A.

10.1101/2020.01.17.910760 — developmental biology — Posted on 2020-01-18

1718 The mouse Balbiani body maintains primordial follicle quiescence via RNA storage

Lei, L.; Ikami, K.; Abbott, H.; Jin, S.

10.1101/2020.01.17.911040 — cell biology — Posted on 2020-01-18

1719 Multifaceted Analysis of Training and Testing Convolutional Neural Networks for Protein Secondary Structure Prediction

Shapovalov, M.; Dunbrack, R. L.; Vucetic, S.

10.1101/2020.01.17.911065 — bioinformatics — Posted on 2020-01-18

1720 A randomized parallel algorithm for efficiently finding near-optimal universal hitting sets

Ekim, B.; Berger, B.; Orenstein, Y.

10.1101/2020.01.17.910513 — bioinformatics — Posted on 2020-01-18

1721 Balance between inhibitory cell types is necessary for flexible frequency switching in adult mouse visual cortex

Domhof, J. W. M.; Tiesinga, P. H. E.

10.1101/2020.01.18.911271 — neuroscience — Posted on 2020-01-18

1722 Laser-facilitated epicutaneous immunotherapy with hypoallergenic beta-glucan neoglycoconjugates suppresses lung inflammation and avoids local side effects in a mouse model of allergic asthma

Korotchenko, E.; Schiessl, V.; Scheiblhofer, S.; Joubert, I.; Strandt, H.; Neuper, T.; Sarajlic, M.; Bauer, R.; Geppert, M.; Joedicke, D.; Wildner, S.; Schaller, S.; Winkler, S.; Gadermaier, G.; Horejs-Hoeck, J.; Weiss, R.

10.1101/2020.01.18.911123 — immunology — Posted on 2020-01-18

1723 Life trajectories towards suicide: developmental role and specificities of adolescence

Notredame, C.-E.; Chawky, N.; Beauchamp, G.; Vaiva, G.; Seguin, M.

10.1101/2020.01.18.911230 — developmental biology — Posted on 2020-01-18

1724 Deciphering the regulatory genome of Escherichiacoli, one hundred promoters at a time

Ireland, W. T. T.; Beeler, S. M.; Flores-Bautista, E.; Belliveau, N. M.; Sweredoski, M. J.; Moradian, A.; Kinney, J. B.; Phillips, R.

10.1101/2020.01.18.910323 — biophysics — Posted on 2020-01-18

1725 Primordial emergence of a nucleic acid binding protein via phase separation and statistical ornithine to arginine conversion

Longo, L. M.; Despotovic, D.; Weil-Ktorza, O.; Walker, M. J.; Jablonska, J.; Fridmann-Sirkis, Y.; Varani, G.; Norman Metanis, N.; Tawfik, D. S.

10.1101/2020.01.18.911073 — biochemistry — Posted on 2020-01-18

1726 Measuring social networks in primates: wearable sensors vs. direct observations

Gelardi, V.; Godard, J.; Paleressompoulle, D.; Claidiere, N.; Barrat, A.

10.1101/2020.01.17.910695 — animal behavior and cognition — Posted on 2020-01-18

1727 Rigor and Transparency Index, a new metric of quality for assessing biological and medical science methods.

Menke, J.; Roelandse, M.; Ozyurt, B. I.; Martone, M. E.; Bandrowski, A. E.

10.1101/2020.01.15.908111 — scientific communication and education — Posted on 2020-01-18

1728 The optoretinogram reveals how human photoreceptors deform in response to light

Pandiyan, V. P.; Bertelli, A. M.; Kuchenbecker, J.; Boyle, K. C.; Ling, T.; Park, B. H.; Roorda, A.; Palanker, D.; Sabesan, R.

10.1101/2020.01.18.911339 — neuroscience — Posted on 2020-01-18

1729 Classification of emotions based on functional connectivity patterns of the human brain

Saarimaki, H.; Glerean, E.; Smirnov, D.; Mynttinen, H.; Jaaskelainen, I. P.; Sams, M.; Nummenmaa, L.

10.1101/2020.01.17.910869 — neuroscience — Posted on 2020-01-18

1730 Competitive exclusion of uropathogenic E. coli biofilm by Salmonella through matrix inhibition

Miryala, S.; S, C.; Chakravarthy, S.

10.1101/2020.01.18.911263 — microbiology — Posted on 2020-01-18

1731 Studies of human twins reveal genetic variation that affects dietary fat perception

Lin, C.; Colquitt, L.; Wise, P.; Breslin, P.; Rawson, N. E.; Genovese, F.; Maina, I.; Joseph, P.; Fomuso, L.; Slade, L.; Brooks, D.; Miclo, A.; Hayes, J.; Sullo, A.; Reed, D. R.

10.1101/2020.01.18.910448 — genetics — Posted on 2020-01-18

1732 Efficient inference, potential, and limitations of site-specific substitution model

Puller, V.; Sagulenko, P.; Neher, R.

10.1101/2020.01.18.911255 — evolutionary biology — Posted on 2020-01-18

1733 A Reaction-Diffusion Network model predicts a dual role of Cactus/IκB to regulate Dorsal/NFκB nuclear translocation in Drosophila

Barros, C. D. T.; Cardoso, M. A.; Bisch, P. M.; Araujo, H. M.; Lopes, F. J. P.

10.1101/2020.01.18.909416 — developmental biology — Posted on 2020-01-18

1734 Coupling of dynamic microtubules to F-actin by Fmn2 regulates chemotaxis of neuronal growth cones

Kundu, T.; Dutta, P.; Nagar, D.; Maiti, S.; Ghose, A.

10.1101/2020.01.18.911131 — cell biology — Posted on 2020-01-18

1735 Hotspots of aberrant enhancer activity in fibrolamellar carcinoma reveal molecular mechanisms of oncogenesis and intrinsic drug resistance

Dinh, T. A.; Sritharan, R.; Smith, F. D.; Francisco, A. B.; Ma, R. K.; Bunaciu, R. P.; Kanke, M.; Danko, C. G.; Massa, A. P.; Scott, J. D.; Sethupathy, P.

10.1101/2020.01.18.911297 — cancer biology — Posted on 2020-01-18

1736 Metalign: Efficient alignment-based metagenomic profiling via containment min hash

LaPierre, N.; Alser, M.; Eskin, E.; Koslicki, D.; Mangul, S.

10.1101/2020.01.17.910521 — bioinformatics — Posted on 2020-01-18

1737 Harmonic-Balance Circuit Analysis for Electro-Neural Interfaces

Chen, Z.; Wang, B.; Palanker, D.

10.1101/2020.01.17.910968 — bioengineering — Posted on 2020-01-18

1738 Feral pigeon populations: their gene pool and links with local domestic breeds

Giunchi, D.; Mucci, N.; Bigi, D.; Mengoni, C.; Baldaccini, N. E.

10.1101/2020.01.18.911198 — zoology — Posted on 2020-01-18

1739 Murine Staphylococcus aureus chronic infection is cured by theory-driven therapy

Hatzikirou, H.; Meyer-Hermann, M.; Zao, G.; Papaxenopoulou, L.; Medina, E.; Schmitz, I.; Katsoulis-Dimitriou, K.; Khailaie, S.

10.1101/2020.01.17.910786 — systems biology — Posted on 2020-01-18

1740 Accurate And Versatile 3D Segmentation Of Plant Tissues At Cellular Resolution

Wolny, A.; Cerrone, L.; Vijayan, A.; Tofanelli, R.; Barro, A. V.; Louveaux, M.; Wenzl, C.; Steigleder, S.; Pape, C.; Bailoni, A.; Duran-Nebreda, S.; Bassel, G.; Lohmann, J. U.; Hamprecht, F. A.; Schneitz, K.; Maizel, A.; Kreshuk, A.

10.1101/2020.01.17.910562 — plant biology — Posted on 2020-01-18

1741 The human and mouse synaptome architecture of excitatory synapses show conserved features.

Curran, O. E.; Qiu, Z.; Smith, C.; Grant, S.

10.1101/2020.01.17.910547 — neuroscience — Posted on 2020-01-18

1742 Modular slowing of resting-state dynamic Functional Connectivity as a marker of cognitive dysfunction induced by sleep deprivation

10.1101/2020.01.17.910810 — neuroscience — Posted on 2020-01-18

1743 Elucidating the complex organization of neural micro-domains in the locust Schistocerca gregaria using dMRI

Shahid, S. S.; Kerskens, C. M.; Burrows, M.; Witney, A. G.

10.1101/2020.01.17.910851 — neuroscience — Posted on 2020-01-18

1744 Individual deviations from normative models of brain structure in a large cross-sectional schizophrenia cohort

Lv, J.; Di Biase, M.; Cash, R. F. H.; Cocchi, L.; Cropley, V.; Klauser, P.; Tian, Y.; Bayer, J.; Schmaal, L.; Cetin-Karayumak, S.; Rathi, Y.; Pasternak, O.; Bousman, C.; Pantelis, C.; Calamante, F.; Zalesky, A.

10.1101/2020.01.17.911032 — neuroscience — Posted on 2020-01-18

1745 Intra-striatal AAV2.retro administration leads to extensive retrograde transport in the rhesus macaque brain: implications for disease modeling and therapeutic development

Weiss, A. R.; Liguore, W. A.; Domire, J. S.; Button, D.; McBride, J. L.

10.1101/2020.01.17.910893 — neuroscience — Posted on 2020-01-18

1746 Allometric scaling strengthens the relationship between eDNA particle concentration and organism abundance in nature

Yates, M. C.; Glaser, D.; Post, J. R.; Cristescu, M. E.; Fraser, D. J.; Derry, A. M.

10.1101/2020.01.18.908251 — ecology — Posted on 2020-01-18

1747 The TMJ disc is a common ancestral feature in all mammals, as evidenced by the presence of a rudimentary disc during monotreme development.

Anthwal, N.; Tucker, A. S.

10.1101/2020.01.17.910471 — developmental biology — Posted on 2020-01-18

1748 Mechanical-control of cell proliferation increases resistance to chemotherapeutic agents

Rizzuti, I.; Mascheroni, P.; Arcucci, S.; Ben-Meriem, Z.; Prunet, A.; Barentin, C.; Riviere, C.; Delanoe-Ayari, H.; Hatzirikou, H.; Julie Guillermet-Guibert, J.; Delarue, M.

10.1101/2020.01.18.910554 — cancer biology — Posted on 2020-01-18

1749 Robust Classification of Immune Subtypes in Cancer

Gibbs, D. L.

10.1101/2020.01.17.910950 — bioinformatics — Posted on 2020-01-18

1750 Stochastic Sampling of Structural Contexts Improves the Scalability and Accuracy of RNA 3D Module Identification

Sarrazin-Gendron, R.; Yao, H.-T.; Reinharz, V.; Oliver, C. G.; Ponty, Y.; Waldispuhl, J.

10.1101/834762 — bioinformatics — Posted on 2020-01-18

1751 Asymmetrical myofiber architecture along the murine tibialis anterior suggests distinct functional regions

Raz, V.

10.1101/2020.01.17.910422 — physiology — Posted on 2020-01-18

1752 Brain aging comprises many modes of structural and functional change with distinct genetic and biophysical associations

Smith, S. M.; Elliott, L. T.; Alfaro-Almagro, F.; McCarthy, P.; Nichols, T. E.; Douaud, G.; Miller, K. L.

10.1101/802686 — neuroscience — Posted on 2020-01-18

1753 Evolution, geographic spreading, and demographic distribution of Enterovirus D68

Hodcroft, E. B.; Dyrdak, R.; Andres, C.; Egli, A.; Reist, J.; Martinez de Artola, D. G.; Alcoba Florez, J.; Niesters, H. G. M.; Anton, A.; Poelman, R.; Reynders, M.; Wollants, E.; Neher, R. A.; Albert, J.

10.1101/2020.01.10.901553 — microbiology — Posted on 2020-01-18

1754 Transcription factors involved in stem cell maintenance are downstream of Slug/Snail2 and repressed by TGF-β in bronchial epithelial progenitors from Chronic Obstructive Pulmonary Disease

de la Grange, P.; Jolly, A.; Courageux, C.; Ben Brahim, C.; Leroy, P.

10.1101/2020.01.17.910406 — genomics — Posted on 2020-01-18

1755 Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations

Chen, M.-H.; Raffield, L. M.; Mousas, A.; Blood-Cell Consortium (BCX2), ; Johnson, A. D.; Reiner, A. P.; Auer, P.; Lettre, G.

10.1101/2020.01.17.910497 — genetics — Posted on 2020-01-18

1756 Variant-specific changes in persistent or resurgent Na+ current in SCN8A-EIEE13 iPSC-derived neurons

Tidball, A. M.; Lopez-Santiago, L. F.; Yuan, Y.; Glenn, T. W.; Margolis, J. L.; Walker, J. C.; Kilbane, E. G.; Isom, L. M.; Parent, J. M.

10.1101/2020.01.16.909192 — neuroscience — Posted on 2020-01-18

1757 Early exposure to broadly neutralizing antibodies may trigger a dynamical switch from progressive disease to lasting control of SHIV infection

Desikan, R.; Raja, R.; Dixit, N. M.

10.1101/548727 — immunology — Posted on 2020-01-18

1758 Radius-Optimized Efficient Template Matching for Lesion Detection from Brain Images

Koley, S.; Dutta, P. K.; Aganj, I.

10.1101/2020.01.10.893099 — neuroscience — Posted on 2020-01-18

1759 Extensive functional repertoire underpins complex behaviours: insights from Parkinson's disease

Sorrentino, P.; Rucco, R.; Baselice, F.; De Micco, R.; Tessitore, A.; Hillebrand, A.; Mandolesi, L.; Breakspear, M.; Gollo, L. L.; Sorrentino, G.

10.1101/823849 — neuroscience — Posted on 2020-01-18

1760 Hormonal and neural correlates of care in active versus observing poison frog parents

Fischer, E. K.; O'Connell, L. A.

10.1101/765503 — neuroscience — Posted on 2020-01-18

1761 Disome-seq reveals widespread ribosome collisions that recruit co-translational chaperones

Zhao, T.; Chen, Y.-M.; Li, Y.; Wang, J.; Chen, S.; Gao, N.; Qian, W.

10.1101/746875 — genomics — Posted on 2020-01-18

1762 Optimal reproductive phenology under size-dependent cannibalism

Takashina, N.; Fiksen, O.

10.1101/840264 — ecology — Posted on 2020-01-18

1763 sgRNA level determines CRISPRi knockdown efficiency in K562 cells

Wang, Y.; Dong, Z.; Jiang, X.; Gong, P.; Lu, J.; Wan, F.

10.1101/2020.01.12.903625 — cancer biology — Posted on 2020-01-18

1764 Developing an endogenous quorum-sensing based CRISPRi circuit for autonomous and tunable dynamic regulation of multiple targets in industrial Streptomyces

Tian, J.; Yang, G.; Gu, Y.; Sun, X.; Lu, Y.; Jiang, W.

10.1101/2020.01.17.910026 — bioengineering — Posted on 2020-01-18

1765 Big Data Reproducibility: Applications in Brain Imaging

Bridgeford, E. W.; Wang, S.; Yang, Z.; Wang, Z.; Xu, T.; Craddock, C.; Dey, J.; Kiar, G.; Gray-Roncal, W.; Priebe, C. E.; Caffo, B.; Milham, M.; Zuo, X.-N.; Consortium for Reliability and Reproducibility, ; Vogelstein, J. T.

10.1101/802629 — neuroscience — Posted on 2020-01-18

1766 Phytochemical screening, GC-MS profiling of invasive cocklebur (Xanthium strumarium)-insect-pathogen interaction and simulated volatile chemical signaling at Northeast China

Iqbal, M.; Feng, Y. L.

10.1101/2020.01.17.910240 — biochemistry — Posted on 2020-01-17

1767 A computational model to unravel the function of amyloid-β peptide in contact with a phospholipid membrane

La Penna, G.; Krupa, P.; Huy, P. D. Q.; Nguyen, H. L.; Li, M. S.

10.1101/2020.01.17.910182 — biophysics — Posted on 2020-01-17

1768 Genome-wide co-expression distributions as a metric to prioritize genes of functional importance

Alexandre, P. A.; Hudson, N. J.; Lehnert, S. A.; Fortes, M. R. S.; Naval-Sanchez, M.; Nguyen, L. T.; Porto-Neto, L. R.; Reverter, A.

10.1101/2020.01.17.910216 — bioinformatics — Posted on 2020-01-17

1769 iterb-PPse: Identification of transcriptional terminators in bacterial by incorporating nucleotide properties into PseKNC

Fan, Y.; Wang, W.; Zhu, Q.

10.1101/2020.01.17.910232 — bioinformatics — Posted on 2020-01-17

1770 Zero-determinant strategies under observation errors in repeated games

Mamiya, A.; Ichinose, G.

10.1101/2020.01.17.910190 — animal behavior and cognition — Posted on 2020-01-17

1771 Competitive approach of invasive cocklebur (Xanthium strumarium) with native weed species diversity in Northeast China

Iqbal, M.; Iram, A.; Liu, M. C.; Feng, Y. L.

10.1101/2020.01.17.910208 — ecology — Posted on 2020-01-17

1772 Pulmonary ductal coarctation and left pulmonary artery interruption; pathology and role of neural crest and second heart field during development

Gittenberger-de Groot, A. C.; Peterson, J. C.; Wisse, L. J.; Roest, A. A. W.; Poelmann, R. E.; Bökenkamp, R.; Elzenga, N. J.; Hazekamp, M.; Bartelings, M. M.; Jongbloed, M. R. M.; DeRuiter, M. C.

10.1101/2020.01.17.910224 — developmental biology — Posted on 2020-01-17

1773 A standardized and reproducible method to measure decision-making in mice

The International Brain Laboratory; Aguillon, V.; Angelaki, D.; Bayer, H. M.; Bonacchi, N.; Carandini, M.; Cazettes, F.; Churchland, A. K.; Chapuis, G.; Dan, Y.; Dewitt, E.; Faulkner, M.; Hamish, F.; Haetzel, L.; Hausser, M.; Hofer, S.; Hu, F.; Khanal, A.; Krasniak, C.; Laranjeira, I.; Mainen, Z.; Meijer, G.; Miska, N.; Mrsic-Flogel, T.; Noel, J.-P.; Pan Vazquez, A.; Sanders, J.; Socha, K.; Terry, R.; Urai, A.; Vergara, H. M.; Wells, M.; Wilson, C.; Witten, I.; Wool, L.; Zador, A.

10.1101/2020.01.17.909838 — neuroscience — Posted on 2020-01-17

1774 Achieving stable dynamics in neural circuits

Kozachkov, L.; Lundqvist, M.; Slotine, J.-J.; Miller, E. K.

10.1101/2020.01.17.910174 — neuroscience — Posted on 2020-01-17

1775 WEGE: A NEW METRIC FOR RANKING LOCATIONS FOR BIODIVERSITY CONSERVATION

Farooq, H.; Anderson, J.; Belluardo, F.; Nanvonamuquitxo, C.; Bennett, D.; Moat, J.; Soares, A.; Faurby, S.; Antonelli, A.

10.1101/2020.01.17.910299 — ecology — Posted on 2020-01-17

1776 Analysis of movement recursions to detect reproductive events and estimate their fate in central place foragers

Picardi, S.; Smith, B. J.; Boone, M. E.; Frederick, P. C.; Cecere, J. G.; Rubolini, D.; Serra, L.; Pirrello, S.; Borkhataria, R. R.; Basille, M.

10.1101/562025 — ecology — Posted on 2020-01-17

1777 Post-translational covalent assembly of CAR and synNotch receptors for programmable antigen targeting

Lohmueller, J.; Butchy, A. A.; Tivon, Y.; Kvorjak, M.; Miskov-Zivanov, N.; Deiters, A.; Finn, O. J.

10.1101/2020.01.17.909895 — synthetic biology — Posted on 2020-01-17

1778 Identification of a novel population of peripheral sensory neuron that regulates blood pressure

Morelli, C.; Castaldi, L.; Brown, S. J.; Streich, L. L.; Websdale, A.; Taberner, F. J.; Cerreti, B.; Barenghi, A.; Blum, K. M.; Sawitzke, J.; Frank, T.; Steffens, L.; Doleschall, B.; Serrao, J.; Lechner, S. G.; Prevedel, R.; Heppenstall, P. A.

10.1101/2020.01.17.909960 — neuroscience — Posted on 2020-01-17

1779 Why most transporter mutations that cause antibiotic resistance are to efflux pumps rather than to import transporters

Mendes, P.; Girardi, E.; Superti-Furga, G.; Kell, D. B.

10.1101/2020.01.16.909507 — microbiology — Posted on 2020-01-17

1780 Invertebrate Community Associated with the Asexual Generation of Bassettia pallida Ashmead (Hymenoptera: Cynipidae)

Weinersmith, K. L.; Forbes, A. A.; Ward, A. K. G.; Brandao-Dias, P. F. P.; Zhang, Y. M.; Egan, S. P.

10.1101/2020.01.17.909648 — ecology — Posted on 2020-01-17

1781 Succinate can shuttle reducing power from the hypoxic retina to the O2-rich pigment epithelium.

Bisbach, C. M.; Hass, D. T.; Robbings, B. M.; Rountree, A. M.; Sadilek, M.; Sweet, I. R.; Hurley, J. B.

10.1101/2020.01.17.909929 — biochemistry — Posted on 2020-01-17

1782 Radula diversification promotes ecomorph divergence in an adaptive radiation of freshwater snails

Hilgers, L.; Hartmann, S.; Pfaender, J.; Lentge-Maass, N.; von Rintelen, T.; Hofreiter, M.

10.1101/2020.01.17.910034 — evolutionary biology — Posted on 2020-01-17

1783 ATX expression from GFAP+ cells is essential for embryonic development

AIDINIS, V.; Sevastou, I.; Ninou, I.

10.1101/2020.01.17.910141 — developmental biology — Posted on 2020-01-17

1784 Non-essential function of KRAB zinc finger gene clusters in retrotransposon suppression

Wolf, G.; de Iaco, A.; Sun, M.-A.; Bruno, M.; Tinkham, M.; Hoang, D.; Mitra, A.; Ralls, S.; Trono, D.; Macfarlan, T.

10.1101/2020.01.17.910679 — genetics — Posted on 2020-01-17

1785 Grassland irrigation and fertilisation alter vegetation height and vegetation within temperature and negatively affect orthopteran populations

Humbert, J.-Y.; Delley, S.; Arlettaz, R.

10.1101/2020.01.17.910042 — ecology — Posted on 2020-01-17

1786 Estrogen attenuates the growth of human papillomavirus positive epithelial cells

Bristol, M. L.; James, C. D.; Wang, X.; Fontan, C. T.; Morgan, I. M.

10.1101/2020.01.16.909986 — cancer biology — Posted on 2020-01-17

1787 Threshold illumination for non-invasive imaging of cells and tissues

Emon, M. A. B.; Knoll, S.; Doha, U.; Baietto, D.; Ladehoff, L.; Sivaguru, M.; Saif, T.

10.1101/2020.01.16.909911 — biophysics — Posted on 2020-01-17

1788 Dynamic core-periphery structure of information sharing networks in entorhinal cortex and hippocampus

Pedreschi, N.; Bernard, C.; Clawson, W.; Quilichini, P. P.; Barrat, A.; Battaglia, D.

10.1101/2020.01.17.910315 — neuroscience — Posted on 2020-01-17

1789 Serum α-Klotho levels correlate with episodic memory changes related to cardiovascular exercise in older adults

Becke, A.; Maass, A.; Kreutz, M. R.; Duezel, E.

10.1101/2020.01.16.908913 — neuroscience — Posted on 2020-01-17

1790 In silico characterization of mechanisms positioning costimulatory and checkpoint complexes in immune synapses

Siokis, A.; Robert, P. A.; Demetriou, P.; Kvalvaag, A.; Valvo, S.; Mayya, V.; Dustin, M. L.; Meyer-Hermann, M.

10.1101/2020.01.16.908723 — immunology — Posted on 2020-01-17

1791 PE5-PPE4-EspG3 trimer structure from mycobacterial ESX-3 secretion system gives insight into cognate substrate recognition by ESX systems

Williamson, Z. A.; Chaton, C. T.; Ciocca, W. A.; Korotkova, N.; Korotkov, K. V.

10.1101/2020.01.16.909523 — biochemistry — Posted on 2020-01-17

1792 Pollen tube-triggered accumulation of NORTIA at the filiform apparatus facilitates fertilization in Arabidopsis thaliana

Yuan, J.; Ju, Y.; Jones, D. S.; Zhang, W.; Lucca, N.; Staiger, C. J.; Kessler, S. A.

10.1101/621599 — plant biology — Posted on 2020-01-17

1793 Control of Slc7a5 sensitivity by the voltage-sensing domain of Kv1 channels

Sharmin, N.; Lamothe, S. M.; Baronas, V. A.; Silver, G.; Hao, Y.; Kurata, H. T.

10.1101/2020.01.17.910059 — neuroscience — Posted on 2020-01-17

1794 Religious Belief and Cognitive Conflict Sensitivity: A Preregistered fMRI Study

Hoogeveen, S.; Snoek, L.; van Elk, M.

10.1101/2020.01.16.899021 — neuroscience — Posted on 2020-01-17

1795 Fear conditioning prompts sparser representations of conditioned threat in primary visual cortex

Yin, S.; Bo, K.; Liu, Y.; Thigpen, N.; Keil, A.; Ding, M.

10.1101/2020.01.16.909085 — neuroscience — Posted on 2020-01-17

1796 Complement C5a impairs phagosomal maturation in the neutrophil through phosphoproteomic remodelling.

Wood, A. J.; Vassallo, A. M.; Ruchard-Sparagano, M.-H.; Scott, J.; Zinnato, C.; Gonzalez-Tejedo, C.; Kishore, K.; D'Santos, C.; Simpson, A. J.; Menon, D.; Summers, C.; Chilvers, E. R.; Okkenhaug, K.; Conway Morris, A.

10.1101/2020.01.17.907618 — immunology — Posted on 2020-01-17

1797 Convergent genetic architecture underlies parallel pelvic reduction in genetically highly structured stickleback species

Kemppainen, P. M.; Li, Z.; Rastas, P.; Loytynoja, A.; Fang, B.; Guo, B.; Shikano, T.; Yang, J.; Merila, J.

10.1101/2020.01.17.908970 — evolutionary biology — Posted on 2020-01-17

1798 Wing shape and environmental energy are associated with molecular evolutionary rates in a large avian radiation

Duchene, D. A.; Valencia, P. A.; Cadena, D. A.

10.1101/2020.01.16.908368 — evolutionary biology — Posted on 2020-01-17

1799 The impact and implications of vehicle collisions on the endangered and endemic Zanzibar red colobus (Piliocolobus kirkii)

Olgun, H.; Mohammed, M. K.; Mzee, A. J.; Green, M. E. L.; Davenport, T. R. B.; Georgiev, A. V.

10.1101/2020.01.17.906909 — ecology — Posted on 2020-01-17

1800 The npBAF to nBAF Chromatin Switch Regulates Cell Cycle Exit in the Developing Mammalian Cortex

Braun, S.; Petrova, R.; Tang, J.; Krokhotin, A.; Miller, E.; Tang, Y.; Panagiotakos, G.; Crabtree, G.

10.1101/2020.01.17.910794 — developmental biology — Posted on 2020-01-17

1801 Retromer retrieves the Wilson Disease protein, ATP7B from lysosomes in a copper-dependent mode

Gupta, A.; Das, S.; Maji, S.; NA, R.; Saha, T.; Bhattacharya, I.

10.1101/2020.01.17.910125 — cell biology — Posted on 2020-01-17

1802 Supraphysiological protection from replication stress does not extend mammalian lifespan

Albers, E.; Avram, A.; Sbroggio, M.; Fernandez-Capetillo, O.; Lopez-Contreras, A. J.

10.1101/2020.01.17.910133 — cancer biology — Posted on 2020-01-17

1803 Stability and dynamics of the human gut microbiome and its association with systemic immune traits

Byrd, A. L.; Liu, M.; Fujimura, K. E.; Lyalina, S.; Nagarkar, D. R.; Charbit, B.; Patin, E.; Harrison, O. J.; Quintana-Murci, L.; Duffy, D.; Albert, M. L.; The Milieu Interieur Consortium,

10.1101/2020.01.17.909853 — microbiology — Posted on 2020-01-17

1804 Biases and Blind-Spots in Genome-Wide CRISPR Knockout Screens

Dede, M.; Kim, E.; Hart, T.

10.1101/2020.01.16.909606 — systems biology — Posted on 2020-01-17

1805 Gene expression in reproductive cell-types isolated in temporal sequence from meiosis to early seed initiation in cowpea (Vigna unguiculata L. Walp)

Gursanscky, N. R.; Marzurkiewicz, D.; Juranic, M.; Johnson, S. D.; Leon, G.; Escobar-Guzman, R.; Salinas-Gamboa, R.; Amasende-Morales, I.; Riboni, M.; Hand, M.; Spriggs, A.; Vielle-Calzada, J.-P.; Koltunow, A. M. G.

10.1101/2020.01.17.909945 — plant biology — Posted on 2020-01-17

1806 Oxygen supply limits the heat tolerance of locusts during the first instar only

Youngblood, J. P.; VandenBrooks, J. M.; Babarinde, O.; Donnay, M. E.; Elliott, D. B.; Fredette-Roman, J.; Angilletta, M. J.

10.1101/2020.01.16.909705 — physiology — Posted on 2020-01-17

1807 Late Holocene land vertebrate fauna from Cueva de los Nesofontes, Western Cuba: stratigraphy, last appearance dates, diversity and paleoecology

Orihuela, J.; Perez Orozco, L.; Alvarez Licourt, J. L.; Viera Munoz, R. A.; Santana Barani, C.

10.1101/2020.01.17.909663 — paleontology — Posted on 2020-01-17

1808 Dissociable neural systems support the learning and transfer of hierarchical control structure

Eichenbaum, A.; Scimeca, J.; D'Esposito, M.

10.1101/2020.01.16.909978 — neuroscience — Posted on 2020-01-17

1809 Accelerated EM Connectome Reconstruction using 3D Visualization and Segmentation Graphs

Hubbard, P. M.; Berg, S.; Zhao, T.; Olbris, D. J.; Umayam, L.; Maitin-Shepard, J.; Januszewski, M.; Katz, W. T.; Neace, E. R.; Plaza, S. M.

10.1101/2020.01.17.909572 — neuroscience — Posted on 2020-01-17

1810 Understanding and predicting ciprofloxacin minimum inhibitory concentration in Escherichia coli with machine learning

Pataki, B. A.; Matamoros, S.; van der Putten, B. C. L.; Remondini, D.; Giampieri, E.; Aytan-Aktug, D.; Hendriksen, R. S.; Lund, O.; Csabai, I.; Schultsz, C.; COMPARE ML-AMR group,

10.1101/806760 — microbiology — Posted on 2020-01-17

1811 Expanded Phylogenetic Diversity and Metabolic Flexibility of Microbial Mercury Methylation

McDaniel, E. A.; Peterson, B.; Stevens, S. L. R.; Tran, P. Q.; Anantharaman, K.; McMahon, K.

10.1101/2020.01.16.909358 — microbiology — Posted on 2020-01-17

1812 Multiplexed Single-cell Metabolic Profiles Organize the Spectrum of Human Cytotoxic T Cells

Hartmann, F. J.; Mrdjen, D.; McCaffrey, E.; Glass, D. R.; Greenwald, N. F.; Bharadwaj, A.; Khair, Z.; Baranski, A.; Baskar, R.; Angelo, M.; Bendall, S. C.

10.1101/2020.01.17.909796 — immunology — Posted on 2020-01-17

1813 Morphological profiling of human T and NK lymphocytes identifies actin-mediated control of the immunological synapse

German, Y.; Vulliard, L.; Rubio, A.; Boztug, K.; Ferrand, A.; Menche, J.; Dupre, L.

10.1101/2020.01.17.910091 — immunology — Posted on 2020-01-17

1814 Mixed Logistic Regression in Genome-WideAssociation Studies

Milet, J.; Perdry, H.

10.1101/2020.01.17.910109 — genomics — Posted on 2020-01-17

1815 Multiplex genetic engineering exploiting pyrimidine salvage pathway-based self-encoded selectable markers

Birstonas, L.; Dallemulle, A.; Lopez-Berges, M. S.; Jacobsen, I. D.; Offterdinger, M.; Abt, B.; Strassburger, M.; Bauer, I.; Schmidt, O.; Sarg, B.; Lindner, H.; Haas, H.; Gsaller, F.

10.1101/2020.01.16.908764 — genetics — Posted on 2020-01-17

1816 The Deep(er) Roots of Eukaryotes and Akaryotes

Harish, A.; Morrison, D. A.

10.1101/2020.01.17.907717 — evolutionary biology — Posted on 2020-01-17

1817 The fungal collaboration gradient dominates the root economics space in plants

Bergmann, J.; Weigelt, A.; van der Plas, F.; Laughlin, D. C.; Kuyper, T. W.; Guerrero-Ramirez, N.; Valverde-Barrantes, O. J.; Bruelheide, H.; Freschet, G. T.; Iversen, C. M.; Kattge, J.; McCormack, M. L.; Meier, I. C.; Rillig, M. C.; Roumet, C.; Semchenko, M.; Sweeney, C. J.; van Ruijven, J.; York, L. M.; Mommer, L.

10.1101/2020.01.17.908905 — ecology — Posted on 2020-01-17

1818 Mechanical Instability of Adherens Junctions Overrides Intrinsic Quiescence of Hair Follicle Stem Cells

Biswas, R.; Banerjee, A.; Lembo, S.; Zhao, Z.; Lakshmanan, V.; Nakasaki, M.; Kutyavin, V.; Wright, G.; Palakodeti, D.; Ross, R.; Jamora, C.; Vasioukhin, V.; Yan, J.; Raghavan, S.

10.1101/2020.01.17.909937 — cell biology — Posted on 2020-01-17

1819 Novel ratio-metric features enable the identification of new driver genes across cancer types

Sudhakar, M.; Rengaswamy, R.; Raman, K.

10.1101/2020.01.17.910075 — cancer biology — Posted on 2020-01-17

1820 mosaicFlye: Resolving long mosaic repeats using long error-prone reads

Bankevich, A.; Pevzner, P.

10.1101/2020.01.15.908285 — bioinformatics — Posted on 2020-01-17

1821 DrawAlignR: An interactive tool for across run chromatogram alignment visualization

Gupta, S.; Sing, J.; Mahmoodi, A.; Rost, H.

10.1101/2020.01.16.909143 — bioinformatics — Posted on 2020-01-17

1822 Developing an endogenous quorum-sensing based CRISPRi circuit for autonomous and tunable dynamic regulation of multiple targets in industrial Streptomyces

Jiang, W.; Lu, Y.; Tian, J.; Yang, G.; Gu, Y.; Sun, X.

10.1101/2020.01.17.910026 — bioengineering — Posted on 2020-01-17

1823 Two pectate lyases from Caldicellulosiruptor bescii with the same CALG domain had distinct properties on plant biomass degradation

Hamouda, H. I.; Ali, N.; Su, H.; Feng, J.; Lu, M.; Li, F.-L.

10.1101/2020.01.16.910000 — biochemistry — Posted on 2020-01-17

1824 Ribosome association primes the stringent factor Rel for recruitment of deacylated tRNA to ribosomal A-site

Takada, H.; Roghanian, M.; Caballero-Montes, J.; Van Nerom, K.; Jimmy, S.; Kudrin, P.; Trebini, F.; Murayama, R.; Akanuma, G.; Garcia-Pino, A.; Hauryliuk, V.

10.1101/2020.01.17.910273 — biochemistry — Posted on 2020-01-17

1825 Dynamic longitudinal behavior in animals exposed to chronic social defeat stress

Wendelmuth, M.; Willam, M.; Todorov, H.; Radyushkin, K.; Gerber, S.; Schweiger, S.

10.1101/2020.01.17.907477 — animal behavior and cognition — Posted on 2020-01-17

1826 Genome-wide search for parent-of-origin allele specific expression in Bombus terrestris.

Marshall, H.; van Zweden, J. S.; Van Geystelen, A.; Benaets, K.; Wäckers, F.; Mallon, E. B.; Wenseleers, T.

10.1101/2020.01.17.909168 — evolutionary biology — Posted on 2020-01-17

1827 Bumblebee worker body size affects new worker production in different resource environments

Kerr, N.; Malfi, R. L.; Williams, N. M.; Crone, E. E.

10.1101/2020.01.16.909135 — ecology — Posted on 2020-01-17

1828 Shift of maternal gut microbiome of Tibetan antelope (Pantholops hodgsonii) during the perinatal period

Shi, Y.; Miao, Z.; Su, J.; Wasser, S. K.

10.1101/2020.01.13.903591 — zoology — Posted on 2020-01-17

1829 Integrative analysis identifies candidate tumor microenvironment and intracellular signaling pathways that define tumor heterogeneity in NF1

Banerjee, J.; Allaway, R. J.; Taroni, J. N.; Baker, A.; Zhang, X.; Moon, C. I.; Pratilas, C.; Blakeley, J. O.; Guinney, J.; Hirbe, A.; Greene, C. S.; Gosline, S. J.

10.1101/2020.01.13.904771 — systems biology — Posted on 2020-01-17

1830 Benchmarking kinetic models of Escherichia coli metabolism

Shepelin, D.; Machado, D.; Nielsen, L. K.; Herrgard, M.

10.1101/2020.01.16.908921 — systems biology — Posted on 2020-01-17

1831 DCyFIR: a high-throughput CRISPR platform for multiplexed G protein-coupled receptor profiling and ligand discovery

Kapolka, N. J.; Taghon, G. J.; Rowe, J. B.; Morgan, W. M.; Enten, J. F.; Isom, D. G.

10.1101/2020.01.16.909325 — pharmacology and toxicology — Posted on 2020-01-17

1832 A gradient from long-term memory to novel cognition: graded transitions through default mode and executive cortex

Wang, X.; Margulies, D. S.; Smallwood, J.; Jefferies, E.

10.1101/2020.01.16.908327 — neuroscience — Posted on 2020-01-17

1833 Hierarchical complexity of the macro-scale neonatal brain

Blesa, M.; Galdi, P.; Cox, S. R.; Sullivan, G.; Stoye, D. Q.; Lamb, G. J.; Quigley, A. J.; Thrippleton, M. J.; Escudero, J.; Bastin, M. E.; Smith, K.; Boardman, J. P.

10.1101/2020.01.16.909150 — neuroscience — Posted on 2020-01-17

1834 Salamander retinal ganglion cell responses to rich stimuli

Sadeghi, K.; Berry, M. J.

10.1101/2020.01.14.906149 — neuroscience — Posted on 2020-01-17

1835 Cortical tracking of speech in noise accounts for reading strategies in children

Destoky, F.; Bertels, J.; Niesen, M.; Wens, V.; Vander Ghinst, M.; Leybaert, J.; Lallier, M.; Ince, R. A. A.; Gross, J.; De Tiege, X.; Bourguignon, M.

10.1101/2020.01.16.907667 — neuroscience — Posted on 2020-01-17

1836 Relating the past with the present: Information integration and segregation during ongoing narrative processing

Chang, C. H. C.; Lazaridi, C.; Yeshurun, Y.; Norman, K. A.; Hasson, U.

10.1101/2020.01.16.908731 — neuroscience — Posted on 2020-01-17

1837 Fast estimation of L1-regularized linear models in the mass univariate setting

Mohr, H.; Ruge, H.

10.1101/2020.01.16.909234 — neuroscience — Posted on 2020-01-17

1838 The hippocampal formation as a hierarchical generative model supporting generative replay and continual learning

Stoianov, I.; Maisto, D.; Pezzulo, G.

10.1101/2020.01.16.908889 — neuroscience — Posted on 2020-01-17

1839 An abstract language of thought for spatial sequences in humans

Al Roumi, F.; Marti, S.; Wang, L.; Amalric, M.; Dehaene, S.

10.1101/2020.01.16.908665 — neuroscience — Posted on 2020-01-17

1840 neuPrint: Analysis Tools for EM Connectomics

Clements, J.; Dolafi, T.; Umayam, L.; Neubarth, N. L.; Berg, S.; Scheffer, L. K.; Plaza, S. M.

10.1101/2020.01.16.909465 — neuroscience — Posted on 2020-01-17

1841 Progesterone modulates theta oscillations in the frontal-parietal network

Riddle, J.; Ahn, S.; McPherson, T.; Girdler, S.; Frohlich, F.

10.1101/2020.01.16.909374 — neuroscience — Posted on 2020-01-17

1842 Encoding of 3D Head Orienting Movements in Primary Visual Cortex

Guitchounts, G.; Masis, J. A.; Wolff, S. B. E.; Cox, D.

10.1101/2020.01.16.909473 — neuroscience — Posted on 2020-01-17

1843 Double-dissociation of frequency-specific contributions of dorso-lateral and dorso-medial prefrontal cortex to familiarity and recollective processes in the primate

Wu, Z.; Kavanova, M.; Hickman, L.; Lin, F.; Boschin, E.; Galeazzi, J. M.; Verhagen, L.; Buckley, M. J.

10.1101/2020.01.16.909812 — neuroscience — Posted on 2020-01-17

1844 A Whole-Brain Regression Method to Identify Individual and Group Variations in Functional Connectivity

Zhao, Y.; Caffo, B. S.; Wang, B.; Li, C.-s. R.; Luo, X.

10.1101/2020.01.16.909580 — neuroscience — Posted on 2020-01-17

1845 Opposing forms of adaptation in mouse visual cortex are controlled by distinct inhibitory microcircuits and gated by locomotion

Heintz, T. G.; Hinojosa, A. J.; Lagnado, L.

10.1101/2020.01.16.909788 — neuroscience — Posted on 2020-01-17

1846 A bright and high-performance genetically encoded Ca2+ indicator based on mNeonGreen fluorescent protein

Zarowny, L.; Aggarwal, A.; Rutten, V.; Kolb, I.; The GENIE Project, ; Patel, R.; Huang, H.-Y.; Chang, Y.-F.; Phan, T.; Kanyo, R.; Ahrens, M.; Allison, W. T.; Podgorski, K.; Campbell, R. E.

10.1101/2020.01.16.909291 — molecular biology — Posted on 2020-01-17

1847 Development of Gene Editing Strategies for Human β-Globin (HBB) Gene Mutations

Kalkan, B. M.; Kala, E. Y.; Yuce, M.; Karadag Alpaslan, M.; Kocabas, F.

10.1101/2020.01.16.908319 — molecular biology — Posted on 2020-01-17

1848 Isolation and complete genome sequencing of Pectobacterium phage Jarilo, representing a novel genus of bacteriophages within the subfamily Autographivirinae

Pedersen, J. S.; Carstens, A. B.; Djurhuus, A. M.; Kot, W.; Hansen, L. H.

10.1101/2020.01.16.909176 — microbiology — Posted on 2020-01-17

1849 Early life stress causes persistent impacts on the microbiome of Atlantic salmon

Uren Webster, T. M.; Consuegra, S.; Garcia de Leaniz, C.

10.1101/2020.01.16.908939 — microbiology — Posted on 2020-01-17

1850 Type-1 IFN primed monocytes in pathogenesis of idiopathic pulmonary fibrosis

Ho, L.-P.; Fraser, E.; Denney, L.; Blirando, K.; Vuppusetty, C.; Antanaviciute, A.; Zheng, Y.; Repapi, E.; Iotchkova, V.; Taylor, S.; Ashley, N.; St Noble, V.; Hoyles, R.; Benamore, R.; Clelland, C.; Rastrick, J.; Hardman, C. S.; Alham, N.; Rigby, R.; Rehwinkel, J.

10.1101/2020.01.16.908749 — immunology — Posted on 2020-01-17

1851 Contrasting population structure and demographic history of cereal aphids in different environmental and agricultural landscapes

Morales-Hojas, R.; Sun, J.; Alvira Iraizoz, F.; Tan, X.; Chen, J.

10.1101/2020.01.16.909077 — evolutionary biology — Posted on 2020-01-17

1852 Maturation of human induced pluripotent stem cell-derived cardiomyocytes for modeling hypertrophic cardiomyopathy

Knight, W. E.; Cao, Y.; Lin, Y.-H.; Sparagna, G. C.; Bai, B.; Zhao, Y.; Chi, C.; Du, Y.; Londono, P.; Reisz, J. A.; Brown, B. C.; Taylor, M. R. G.; Ambardekar, A. V.; Cleveland, J. C.; McKinsey, T. A.; Jeong, M. Y.; Walker, L. A.; Woulfe, K. C.; D'Alessandro, A.; Chatfield, K. C.; Xu, H.; Bristow, M. R.; Buttrick, P. M.; Song, K.

10.1101/2020.01.16.909598 — cell biology — Posted on 2020-01-17

1853 Dynamical determinants of different spine movements and gait speeds in rotary and transverse gallops

Kamimura, T.; Aoi, S.; Higurashi, Y.; Wada, N.; Tsuchiya, K.; Matsuno, F.

10.1101/2020.01.16.909481 — bioinformatics — Posted on 2020-01-17

1854 Accumulation of an unprecedented 5'-deoxyadenos-4'-yl radical unmasks the kinetics of the radical-mediated C-C bond formation step in MoaA catalysis

Pang, H.; Lilla, E. A.; Zhang, P.; Zhang, D.; Shields, T. P.; Scott, L. G.; Yang, W.; Yokoyama, K.

10.1101/2020.01.16.909697 — biochemistry — Posted on 2020-01-17

1855 Substrate-dependent accessibility changes in the Na+-dependent C4-dicarboxylate transporter, VcINDY, suggest differential substrate effects in a multistep mechanism.

Mulligan, C.; Sampson, C. D. D.; Stewart, M. J.; Mindell, J. A.

10.1101/2020.01.16.902445 — biochemistry — Posted on 2020-01-17

1856 The relationship between longevity and diet is genotype dependent and sensitive to desiccation

McCracken, A. W.; Buckle, E.; Simons, M. J.

10.1101/2020.01.16.908996 — evolutionary biology — Posted on 2020-01-17

1857 Expected impacts of climate change on tree ferns distribution and diversity patterns in subtropical Atlantic Forest

de Gasper, A. L.; Grittz, G. S.; Russi, C. H.; Rodrigues, A. V.; Schwartz, C. E.

10.1101/2020.01.16.909614 — ecology — Posted on 2020-01-17

1858 Cell signaling coordinates global Polycomb Repressive Complex 2 recruitment and gene expression in murine embryonic stem cells

Aljazi, M. B.; Gao, Y.; Wu, Y.; Mias, G. I.; He, J.

10.1101/597674 — genetics — Posted on 2020-01-17

1859 Quantitative genetics of temperature performance curves of Neurospora crassa

Moghadam, N. N.; Sidhu, K.; Summanen, P. A. M.; Ketola, T.; Kronholm, I.

10.1101/2020.01.16.909093 — evolutionary biology — Posted on 2020-01-17

1860 Strong intracellular signal inactivation produces sharper and more robust signaling from cell membrane to nucleus

Ma, J.; Do, M.; Le Gros, M. A.; Peskin, C. S.; Larabell, C. A.; Mori, Y.; Isaacson, S. A.

10.1101/2020.01.16.909333 — biophysics — Posted on 2020-01-17

1861 A hierarchical clustering and data fusion approach for disease subtype discovery

Pfeifer, B.; Schimek, M. G.

10.1101/2020.01.16.909382 — bioinformatics — Posted on 2020-01-17

1862 Characterisation of the genetic architecture of immune-mediated disease through informed dimension reduction

Burren, O. S.; Reales, G.; Wong, L.; Bowes, J.; Lee, J. C.; Barton, A.; Lyons, P. A.; Smith, K. G.; Thomson, W.; Kirk, P. D.; Wallace, C.

10.1101/2020.01.14.905869 — genetics — Posted on 2020-01-17

1863 Enhancing georeferenced biodiversity inventories: automated information extraction from literature records reveal the gaps

Kopperud, B. T.; Lidgard, S.; Liow, L. H.

10.1101/2020.01.16.908962 — ecology — Posted on 2020-01-17

1864 Activation of cryptic splicing in bovine WDR19 is associated with reduced semen quality and male fertility

Hiltpold, M.; Niu, G.; Kadri, N. K.; Crysnanto, D.; Fang, Z.-H.; Spengeler, M.; Schmitz-Hsu, F.; Fuerst, C.; Schwarzenbacher, H.; Seefried, F. R.; Fries, R.; Seehusen, F.; Schnieke, A.; Bollwein, H.; Flisikowski, K.; Pausch, H.

10.1101/2020.01.16.907865 — genomics — Posted on 2020-01-17

1865 Methods for analysing lineage tracing datasets

Kostiou, V.; Zhang, H.; Hall, M. W. J.; Jones, P. H.; Hall, B. A.

10.1101/2020.01.11.901819 — systems biology — Posted on 2020-01-17

1866 Dopamine Promotes Cognitive Effort by Biasing the Benefits Versus Costs of Cognitive Work

Westbrook, A.; van den Bosch, R.; Määttä, J.; Hofmans, L.; Papadopetraki, D.; Cools, R.; Frank, M. J.

10.1101/778134 — neuroscience — Posted on 2020-01-17

1867 Sensitization of knee-innervating sensory neurons by tumor necrosis factor-α activated fibroblast-like synoviocytes: an in vitro, co-culture model of inflammatory pain

Chakrabarti, S.; Hore, Z.; Pattison, L. A.; Lalnunhlimi, S.; Bhebhe, C. N.; Callejo, G.; Bulmer, D. C.; Taams, L. S.; Denk, F.; Smith, E. S. J.

10.1101/791251 — neuroscience — Posted on 2020-01-17

1868 Inhibition of protein synthesis in M1 of monkeys disrupts performance of sequential movements guided by memory

Ohbayashi, M.

10.1101/818674 — neuroscience — Posted on 2020-01-17

1869 Auto-regulatory J-domain interactions control Hsp70 recruitment in the oligomeric DNAJB8 co-chaperone

Ryder, B. D.; Matlahov, I.; Bali, S.; Vaquer-Alicea, J.; Van der Wel, P. C. A.; Joachimiak, L. A.

10.1101/2020.01.09.899237 — biochemistry — Posted on 2020-01-17

1870 The connector between the kinase and RNase domains of IRE1α transmits the conformational change that underlies ER stress-induced activation.

Ricci, D.; Tutton, S.; Marrocco, I.; Ying, M.; Blumenthal, D.; Eletto, D.; Vargas, J.; Boyle, S.; Fazelinia, H.; Paton, J. C.; Paton, A. W.; Tang, C.-H. A.; Hu, C.-C. A.; Gidalevitz, T.; Argon, Y.

10.1101/2020.01.14.902395 — biochemistry — Posted on 2020-01-17

1871 Towards an information theory of quantitative genetics

Galas, D. J.; Kunert-Graf, J. M.; Uechi, L.; Sakhanenko, N. A.

10.1101/811950 — genetics — Posted on 2020-01-17

1872 Optimising DNA-Coated Gold Nanoparticles to Enrich Skeletal Stem Cells from Human Bone Marrow Samples

Lanham, S.; Xavier, M.; Kyriazi, M.; Alexaki, K.; El-Sagheer, A.; Brown, T.; Kanaras, A.; Oreffo, R. O. C.

10.1101/2019.12.19.882563 — cell biology — Posted on 2020-01-17

1873 Commensal bacteria differentially shape the nutritional requirements of Drosophila during juvenile growth

Consuegra, J.; Grenier, T.; Baa-Puyoulet, P.; Rahioui, I.; Akherraz, H.; Gervais, H.; Parisot, N.; da Silva, P.; Charles, H.; Calevro, F.; Leulier, F.

10.1101/728774 — microbiology — Posted on 2020-01-17

1874 An atlas of the tissue and blood metagenome in cancer reveals novel links between bacteria, viruses and cancer

Borchmann, S.

10.1101/773200 — genomics — Posted on 2020-01-17

1875 An African origin for Mycobacterium bovis

Loiseau, C. M.; Menardo, F.; Aseffa, A.; Hailu, E.; Gumi, B.; Ameni, G.; Berg, S.; Rigouts, L.; Robbe-Austerman, S.; Zinsstag, J.; Gagneux, S.; Brites, D.

10.1101/773192 — evolutionary biology — Posted on 2020-01-17

1876 The plant mobile domain proteins MAIN and MAIL1 interact with the phosphatase PP7L to regulate gene expression and silence transposable elements in Arabidopsis thaliana.

Nicolau, M.; Picault, N.; Descombin, J.; Jami-Alahmadi, Y.; Feng, S.; Bucher, E.; Jacobsen, S. E.; Deragon, J.-M.; Wohlschlegel, J.; Moissiard, G.

10.1101/710905 — plant biology — Posted on 2020-01-17

1877 Timescales of motor memory formation in dual-adaptation

Forano, M.; Franklin, D. W.

10.1101/698167 — neuroscience — Posted on 2020-01-17

1878 A general in vitro assay to study enzymatic activities of the ubiquitin system

Zuo, Y.; Chong, B. K.; Jiang, K.; Finley, D.; Klenerman, D.; Ye, Y.

10.1101/660894 — biochemistry — Posted on 2020-01-17

1879 The Fes tyrosine kinase guides CD19 receptor fate in B-cells by shaping regulatory Src phosphorylation networks

Helbig, A. O.; Kofler, M.; Gish, G.; Lorenzen, K.; Tucholska, M.; Zhang, C.; Roth, F. P.; Colwill, K.; Pawson, T.; Petsalaki, E.

10.1101/125088 — systems biology — Posted on 2020-01-17

1880 Dynamic Functional Connectivity between Order and Randomness and its Evolution across the Human Adult Lifespan

Battaglia, D.; Thomas, B.; Hansen, E. C.; Lombardo, D.; Chettouf, S.; Daffertshofer, A.; McIntosh, A. R.; Zimmermann, J.; Ritter, P.; Jirsa, V.

10.1101/107243 — neuroscience — Posted on 2020-01-17

1881 Serial protein crystallography in an electron microscope

Bücker, R.; Hogan-Lamarre, P.; Mehrabi, P.; Schulz, E. C.; Bultema, L. A.; Gevorkov, Y.; Brehm, W.; Yefanov, O.; Oberthür, D.; Kassier, G. H.; Miller, R. J. D.

10.1101/682575 — molecular biology — Posted on 2020-01-17

1882 Non-Invasive Detection of Viral Antibodies Using Oral Flocked Swabs

Speicher, D. J.; Luinstra, K.; Smith, E. J.; Castriciano, S.; Smieja, M.

10.1101/536227 — microbiology — Posted on 2020-01-17

1883 Whole-genome sequencing of rare disease patients in a national healthcare system

Ouwehand, W. H.

10.1101/507244 — genomics — Posted on 2020-01-17

1884 Animal, fungi, and plant genome sequences harbour different non-canonical splice sites

Frey, K.; Pucker, B.

10.1101/616565 — genomics — Posted on 2020-01-17

1885 Topoisomerases modulate the timing of meiotic DNA breakage and chromosome morphogenesis in Saccharomyces cerevisiae

Heldrich, J.; Sun, X.; Vale-Silva, L. A.; Markowitz, T. E.; Hochwagen, A.

10.1101/672337 — genomics — Posted on 2020-01-17

1886 Relative distances between homology groups to assess persistent defects in time series

Diaz Ochoa, J.

10.1101/595785 — bioinformatics — Posted on 2020-01-17

1887 Stoichiometric homeostasis of wetland vegetation along a nutrient gradient in a subtropical wetland. Understanding stoichiometric mechanisms of nutrient retention in wetland macrophytes.

Julian, P.; Gerber, S.; Bhomia, R. K.; King, J.; Osborne, T. Z.; Wright, A. L.

10.1101/221465 — ecology — Posted on 2020-01-17

1888 sigfit: flexible Bayesian inference of mutational signatures

Gori, K.; Baez-Ortega, A.

10.1101/372896 — cancer biology — Posted on 2020-01-17

1889 Cyclodextrin polymer coatings resist protein fouling, mammalian cell adhesion, and bacterial attachment

Learn, G. D.; Lai, E. J.; von Recum, H. A.

10.1101/2020.01.16.909564 — bioengineering — Posted on 2020-01-17

1890 Resolving mechanisms of immune-mediated disease in primary CD4 T cells

Bourges, C.; Groff, A. F.; Burren, O. S.; Gerhardinger, C.; Mattioli, K.; Hutchinson, A.; Hu, T.; Anand, T.; Epping, M. W.; Wallace, C.; Smith, K. G. C.; Rinn, J.; Lee, J. C.

10.1101/2020.01.16.908988 — genetics — Posted on 2020-01-17

1891 A hybrid spectral library combining DIA-MS data and a targeted virtual library substantially deepens the proteome coverage

Lou, R.; Tang, P.; Ding, K.; Li, S.; Tian, C.; Li, Y.; Zhao, S.; Zhang, Y.; Shui, W.

10.1101/2020.01.16.909952 — bioinformatics — Posted on 2020-01-17

1892 Impact of DNA sequences in the DNA duplex opening by the Rad4/XPC nucleotide excision repair complex

Min, J. H.; Broyde, S.; Paul, D.; Mu, H.; Dai, Q.; Tavakoli, A.; He, C.

10.1101/2020.01.16.909549 — biochemistry — Posted on 2020-01-17

1893 Pulmonary ductal coarctation and left pulmonary artery interruption; pathology and role of neural crest and second heart field during development

Gittenberger-de Groot, A. C.; Peterson, J. C.; Wisse, L. J.; Roest, A. A. W.; Poelmann, R. E.; Bökenkamp, R.; Elzenga, N. J.; Hazekamp, M.; Bartelings, M. M.; Jongbloed, M. R. M.; DeRuiter, M. C.

10.1101/2020.01.17.910224 — developmental biology — Posted on 2020-01-17

1894 Norway spruce deploys tissue specific canonical responses to acclimate to the cold

Vergara, A.; Haas, J. C.; Stachula, P.; Street, N. R.; Hurry, V.

10.1101/2020.01.13.904805 — plant biology — Posted on 2020-01-17

1895 Ecological patterns of root nodule diversity in cultivated and wild rooibos populations: a community prediction approach

Ramoneda, J.; Le Roux, J.; Frossard, E.; Frey, B.; Gamper, H. A.

10.1101/2020.01.15.907972 — ecology — Posted on 2020-01-17

1896 Competitive approach of invasive cocklebur (Xanthium strumarium) with native weed species diversity in Northeast China

Iqbal, M.; Iram, A.; Liu, M. C.; Feng, Y. L.

10.1101/2020.01.17.910208 — ecology — Posted on 2020-01-17

1897 Iterative Refinement of Cellular Identity from Single-Cell Data Using Online Learning

Gao, C.; Welch, J. D.

10.1101/2020.01.16.909861 — bioinformatics — Posted on 2020-01-17

1898 Fusion Pore Formation Observed During SNARE-Mediated Vesicle Fusion with Pore-Spanning Membranes

Mühlenbrock, P.; Herwig, K.; Vuong, L.; Mey, I.; Steinem, C.

10.1101/2020.01.16.909044 — biophysics — Posted on 2020-01-17

1899 Efficient approximations for stationary single-channel Ca2+ nanodomains across length scales

Chen, Y.; Muratov, C. B.; Matveev, V.

10.1101/2020.01.16.909036 — biophysics — Posted on 2020-01-17

1900 Large-scale multivariate multi-ancestry Interaction analyses point towards different genetic mechanisms by population and exposure.

Laville, V.; Majarian, T.; Sung, Y. J.; Feitosa, M. F.; Chasman, D.; Bentley, A. R.; Rotimi, C. N.; Cupples, A. L.; de Vries, P. S.; Brown, M. R.; Morrison, A. C.; Kraja, A. T.; Province, M.; Schwander, K.; Gauderman, J.; Rao, D.; Manning, A.; Aschard, H.

10.1101/562157 — genetics — Posted on 2020-01-17

1901 Exact distribution of divergence times from fossil ages and tree topologies

Didier, G.; Laurin, M.

10.1101/490003 — evolutionary biology — Posted on 2020-01-17

1902 A new phylogenetic protocol: Dealing with model misspecification and confirmation bias in molecular phylogenetics

Jermiin, L. S.; Catullo, R. A.; Holland, B. R.

10.1101/400648 — evolutionary biology — Posted on 2020-01-17

1903 A novel G protein-biased and subtype selective agonist for a G protein-coupled receptor discovered from screening herbal extracts

Zhang, B.; Zhao, S.; Yang, D.; Wu, Y.; Xin, Y.; Cao, H.; Huang, X.-P.; Cai, X.; Sun, W.; Ye, N.; Xu, Y.; Peng, Y.; Zhao, S.; Liu, Z.-J.; Zhong, G.; Wang, M.-W.; Shui, W.

10.1101/2019.12.22.883686 — biochemistry — Posted on 2020-01-17

1904 The molecular aetiology of tRNA synthetase depletion: induction of a GCN4 amino acid starvation response despite homeostatic maintenance of charged tRNA levels

McFarland, M. R.; Keller, C. D.; Childers, B. M.; Adeniyi, S. A.; Corrigall, H.; Raguin, A.; Romano, M. C.; Stansfield, I.

10.1101/610790 — systems biology — Posted on 2020-01-17

1905 The phylogenetic range of bacterial and viral pathogens of vertebrates

Shaw, L. P.; Wang, A. D.; Dylus, D.; Meier, M.; Pogacnik, G.; Dessimoz, C.; Balloux, F.

10.1101/670315 — ecology — Posted on 2020-01-17

1906 Movement behavioral plasticity of benthic diatoms driven by optimal foraging

Hu, W.-S.; Huang, M.-J.; Zhang, H.-P.; Zhang, F.; Vyverman, W.; Liu, Q.-X.

10.1101/682153 — ecology — Posted on 2020-01-17

1907 Learning steers the ontogeny of an efficient hunting sequence in zebrafish larvae.

Lagogiannis, K.; Diana, G.; Meyer, M. P.

10.1101/2019.12.19.883157 — animal behavior and cognition — Posted on 2020-01-17

1908 Preliminary Evaluation of the Utility of Deep Generative Histopathology Image Translation at a Mid-Sized NCI Cancer Center

Levy, J. J.; Jackson, C. R.; Sriharan, A.; Christensen, B.; Vaickus, L. J.

10.1101/2020.01.07.897801 — pathology — Posted on 2020-01-17

1909 Functional brain network reconfiguration during learning in a dynamic environment

Kao, C.-H.; Khambhati, A. N.; Bassett, D. S.; Nassar, M. R.; McGuire, J. T.; Gold, J. I.; Kable, J. W.

10.1101/800284 — neuroscience — Posted on 2020-01-17

1910 Human revealed preferences for multi-component rewards

Pastor-Bernier, A.; Volkmann, K.; Stasiak, A.; Grabenhorst, F.; Schultz, W.

10.1101/832881 — neuroscience — Posted on 2020-01-17

1911 Adhesion force spectroscopy with nanostructured colloidal probes reveals nanotopography-dependent early mechanotransductive interactions at the cell membrane level

Chighizola, M.; Previdi, A.; Dini, T.; Piazzoni, C.; Lenardi, C.; Milani, P.; Schulte, C.; Podesta', A.

10.1101/2020.01.02.892919 — biophysics — Posted on 2020-01-17

1912 Development of a soft cell confiner to decipher the impact of mechanical stimuli on cells

Prunet, A.; Lefort, S.; Delanoe-Ayari, H.; Saci, S.; Simon, G.; Argoul, F.; Guyot, B.; Rieu, J.-P.; Gobert, S.; Maguer-Satta, V.; Riviere, C.

10.1101/2020.01.04.892695 — biophysics — Posted on 2020-01-17

1913 Epidermal Growth Factor single mutants highlighted by homologs cross-conservation approach differentially affect the EGF Receptor downstream pathway

Merzhakupova, D.; pascarelli, s.; Laurino, P.

10.1101/677393 — bioinformatics — Posted on 2020-01-17

1914 The Architecture of GluD2 Ionotropic Delta Glutamate Receptor Elucidated by cryo-EM

Burada, A. P.; Kumar, J.

10.1101/2020.01.10.902072 — biochemistry — Posted on 2020-01-17

1915 Perturbation analysis of a multi-morphogen Turing Reaction-Diffusion stripe patterning system reveals key regulatory interactions

Economou, A. D.; Monk, N. A. M.; Green, J. B. A.

10.1101/2019.12.27.889493 — developmental biology — Posted on 2020-01-17

1916 A HaloTag-TEV genetic cassette for mechanical phenotyping of proteins from tissues

Rivas-Pardo, J. A.; Li, Y.; Martonfalvi, Z.; Tapia-Rojo, R.; Unger, A.; Fernandez-Trasancos, A.; Herrero-Galan, E.; Velazquez-Carreras, D.; Fernandez, J. M.; Linke, W. A.; Alegre-Cebollada, J.

10.1101/577445 — biophysics — Posted on 2020-01-17

1917 Computational modelling of cambium activity provides a regulatory framework for simulating radial plant growth

Lebovka, I.; Mele, B. H.; Zakieva, A.; Gursanscky, N.; Merks, R. M. H.; Greb, T.

10.1101/2020.01.16.908715 — plant biology — Posted on 2020-01-17

1918 Rice NIN-LIKE PROTEIN 4 is a master regulator of nitrogen use efficiency

Wu, J.; Zhang, Z.-S.; Xia, J.-Q.; Alfatih, A.; Song, Y.; Huang, Y.-J.; Wan, G.-Y.; Sun, L.-Q.; Tang, H.; Liu, Y.; Wang, S.-M.; Zhu, Q.-S.; Qin, P.; Wang, Y.-P.; Li, S.-G.; Mao, C.-Z.; Zhang, G.-Q.; Chu, C.-C.; Yu, L.-H.; Xiang, C.

10.1101/2020.01.16.908558 — plant biology — Posted on 2020-01-17

1919 Enterobacter sp. SA187 mediates plant thermotolerance by chromatin modification of heat stress genes

Shekhawat, K.; Sheikh, A.; Mariappan, K.; Jalal, R.; Hirt, H.

10.1101/2020.01.16.908756 — plant biology — Posted on 2020-01-17

1920 New virus isolates from Italian hydrothermal environments underscore the biogeographic pattern in archaeal virus communities

Baquero, D. P.; Contursi, P.; Piochi, M.; Bartolucci, S.; Liu, Y.; Cvirkaite-Krupovic, V.; Prangishvili, D.; Krupovic, M.

10.1101/2020.01.16.907410 — microbiology — Posted on 2020-01-17

1921 Genetic interactions shaping evolutionary trajectories in an RNA virus population

Chang, C.; Bianco, S.; Acevedo, A.; Tang, C.; Andino, R.

10.1101/2020.01.16.908129 — evolutionary biology — Posted on 2020-01-17

1922 Coalescence of rhizobial communities in soil interacts with fertilization and determines the assembly of rhizobia in root nodules

Ramoneda, J.; Le Roux, J.; Stadelmann, S.; Frossard, E.; Frey, B.; Gamper, H. A.

10.1101/2020.01.16.908863 — ecology — Posted on 2020-01-17

1923 Proteome specialization of anaerobic fungi during ruminal degradation of recalcitrant plant fiber

10.1101/2020.01.16.907998 — microbiology — Posted on 2020-01-17

1924 Evolutionary context-integrated deep sequence modeling for protein engineering

Luo, Y.; Vo, L.; Ding, H.; Su, Y.; Liu, Y.; Qian, W.; Zhao, H.; Peng, J.

10.1101/2020.01.16.908509 — bioinformatics — Posted on 2020-01-17

1925 Structure of the Xylan O-Acetyltransferase AtXOAT1 Reveals Molecular Insight into Polysaccharide Acetylation in Plants

Urbanowicz, B.; Lunin, V.; Wang, H.-T.; Bharadwaj, V.; Alahuhta, P. M.; Pena, M. J.; Yang, J.-Y.; Archer-Hartmann, S. A.; Azadi, P.; Himmel, M.; Moremen, K. W.; York, W. S.; Bomble, Y. J.

10.1101/2020.01.16.909127 — biochemistry — Posted on 2020-01-17

1926 Transcytosis via the late endocytic pathway as a cell morphogenetic mechanism

Mathew, R.; Rios-Barrera, L. D.; Machado, P.; Schwab, Y.; Leptin, M.

10.1101/2020.01.16.909200 — cell biology — Posted on 2020-01-16

1927 Golgi SM protein Sly1 promotes productive trans-SNARE complex assembly through multiple mechanisms

Duan, M.; Gao, G.; Banfield, D. K.; Merz, A. J.

10.1101/2020.01.16.909630 — cell biology — Posted on 2020-01-16

1928 Serological evidence of exposure to Rift Valley, Dengue and Chikungunya Viruses among agropastoral communities in Manyara and Morogoro regions in Tanzania: A community Survey

Budodo, R. M.; Horumpende, P. G.; Mkumbaye, S. I.; Mmbaga, B. T.; Mwakapuja, R. S.; Chilongola, J.

10.1101/2020.01.16.908830 — microbiology — Posted on 2020-01-16

1929 Loss of Caveolin-1 and caveolae leads to increased cardiac cell stiffness and functional decline of the adult zebrafish heart

de la Pompa, J. L.; Grivas, D.; Gonzalez-Rajal, A.; Guerrero Rodriguez, C.; Garcia, R.

10.1101/2020.01.16.909267 — developmental biology — Posted on 2020-01-16

1930 Counteracting Genome Instability by p53-dependent Mintosis

Liang, J.; Niu, Z.; Yu, X.; Zhang, B.; Wang, M.; Ruan, B.; Qin, H.; Zhang, X.; Zheng, Y.; Gu, S.; Sai, X.; Tai, Y.; Gao, L.; Ma, L.; Chen, Z.; Huang, H.; Wang, X.; Sun, Q.

10.1101/2020.01.16.908954 — cell biology — Posted on 2020-01-16

1931 Dissecting the nanoscale lipid profile of caveolae

Zhou, Y.; Ariotti, N.; Rae, J.; Liang, H.; Tillu, V.; Tee, S.; Bastiani, M.; Bademosi, A. T.; Collins, B.; Meunier, F. A.; Hancock, J. F.; Parton, R. G.

10.1101/2020.01.16.909408 — biochemistry — Posted on 2020-01-16

1932 Core Role of TRPC6 in Regulating Airway Re-modelling in Chronic Obstructive Pulmonary Disease

Hao, Q.; Zhao, K.; Xie, R.; Gu, W.; Wei, J.; Fei, Z.

10.1101/2020.01.16.908699 — cell biology — Posted on 2020-01-16

1933 A Cross-Sectional Study of the Prevalence and Risk Factors of Soil Transmitted Helminthes Infection and Stunting Among School-aged Children in Ibadan

Ibrahim, A. G.; Tijani, M.; Nwuba, R.

10.1101/2020.01.16.908848 — molecular biology — Posted on 2020-01-16

1934 A decade of arbovirus emergence in the temperate southern cone of South America: dengue, Aedes aegypti and climate dynamics in Cordoba, Argentina

Estallo, E. L.; Sippy, R.; Stewart-Ibarra, A. M.; Grech, M. G.; Benitez, E. M.; Luduena-Almeida, F. F.; Ainete, M.; Frias-Cespedes, M.; Robert, M.; Romero, M. M.; Almiron, W. R.

10.1101/2020.01.16.908814 — ecology — Posted on 2020-01-16

1935 Wheelchair user's voice: a pilot study in Indonesia

D'Innocenzo, M.; Vasquez, S. G.; Pearlman, J.; Zigler, C.; Mendez, Y. G.; Rozen, P.; Dewi, E. H.; Praptoraharjo, I.

10.1101/2020.01.16.908772 — bioengineering — Posted on 2020-01-16

1936 Pterostilbene Protects Cochlea from Ototoxicity in Streptozotocin-Induced Diabetic Rats by Inhibiting the Apoptosis

ÖZDAS, S.; TASTEKIN, B.; GÜRGEN, S. G.; ÖZDAS, T.; PELIT, A.; ERKAN, S. O.; TUHANIOGLU, B.; GÖRGÜLÜ, O.

10.1101/2020.01.16.908798 — neuroscience — Posted on 2020-01-16

1937 Human MAIT cell cytolytic effector proteins synergize to overcome carbapenem resistance in Escherichia coli

Boulouis, C.; Sia, W. R.; Gulam, M. Y.; Teo, J. Q. M.; Phan, T. K.; Mak, J. Y. W.; Fairlie, D. P.; Poon, I. K. H.; Koh, T. H.; Bergman, P.; Wang, L.-F.; Kwa, A. L. H.; Sandberg, J. K.; Leeansyah, E.

10.1101/2020.01.16.908806 — immunology — Posted on 2020-01-16

1938 Spatio-temporal patterns of wildfires in the Niassa Reserve -Mozambique, using remote sensing data.

Nhongo, E. J. S.; Fontana, D.; Guasselli, L.

10.1101/2020.01.16.908780 — ecology — Posted on 2020-01-16

1939 The inhibition of cellular toxicity of amyloid-beta by dissociated transthyretin

Saelices, L.; Cao, Q.; Anderson, D. H.; Liang, W. Y.; Chou, J.; Eisenberg, D. S.

10.1101/852715 — biochemistry — Posted on 2020-01-16

1940 Invitro-Propagation of Threatened African Sandalwood (Osyris lanceolata Hochst. & Steud.) via Using IBA hormone

Admas, A. M.; Melese, S.; Genetu, A.; Yilma, Z.; Kidane, B.; Admasu, M.; Misega, T.

10.1101/2020.01.15.908566 — plant biology — Posted on 2020-01-16

1941 A single bacterial genus maintains root development in a complex microbiome

Finkel, O. M.; Salas-Gonzalez, I.; Castrillo, G.; Conway, J. M.; Law, T. F.; Lima Teixeira, P. J. P.; Wilson, E. D.; Fitzpatrick, C. R.; Jones, C. D.; Dangl, J. L.

10.1101/645655 — microbiology — Posted on 2020-01-16

1942 Linkage Disequilibrium and Heterozygosity Modulate the Genetic Architecture of Human Complex Phenotypes: Evidence of Natural Selection from GWAS Summary Statistics

Holland, D.; Frei, O.; Desikan, R.; Fan, C. C.; Shadrin, A.; Smeland, O.; Andreassen, O. A.; Dale, A.

10.1101/705285 — genomics — Posted on 2020-01-16

1943 The regulation of mammalian maternal-to-embryonic transition by Eukaryotic translation initiation factor 4E

JIN, X.; Li, Y.; Huang, X.; Tang, J.; Ji, X.; Liu, M.; CHANG, L.; LIU, J.; GU, Y.; Shi, C.; Ni, W.; Shi, H.-j.; O'Neill, C.

10.1101/2020.01.16.908582 — developmental biology — Posted on 2020-01-16

1944 Ancestral Haplotype Reconstruction in Endogamous Populations using Identity-By-Descent

Finke, K.; Kourakos, M.; Brown, G.; Simons, Y. B.; Schaffer, A. A.; Kember, R. L.; Bucan, M.; Mathieson, S.

10.1101/2020.01.15.908459 — bioinformatics — Posted on 2020-01-16

1945 One-stop Microfluidic Assembly of Human Brain Organoids to Model Prenatal Cannabis Exposure

Ao, Z.; Cai, H.; Havert, D.; Wu, Z.; Gong, Z.; Beggs, J.; Mackie, K.; Guo, F.

10.1101/2020.01.15.908483 — bioengineering — Posted on 2020-01-16

1946 Regeneration in adult Drosophila brain

Crocker, K. L.; Marischuk, K.; Rimkus, S. A.; Zhou, H.; Yin, J. C. P.; Boekhoff-Falk, G. E.

10.1101/2020.01.16.908640 — neuroscience — Posted on 2020-01-16

1947 Experimental Evolution in vivo to Identify Selective Pressures During Pneumococcal Colonization

Cooper, V. S.; Honsa, E.; Rowe, H.; Deitrick, C.; Iverson, A. R.; Whittall, J. J.; Neville, S. L.; McDevitt, C. A.; Kietzman, C.; Rosch, J. W.

10.1101/2020.01.15.908590 — microbiology — Posted on 2020-01-16

1948 Cryo-EM structures of cardiac thin filaments reveal the 3D architecture of troponin.

Oda, T.; Yanagisawa, H.; Wakabayashi, T.

10.1101/2020.01.15.908418 — biochemistry — Posted on 2020-01-16

1949 In vitro activities of the tetrazole SHR8008 compared to itraconazole and fluconazole against Candida and Cryptococcus species

Wang, L.; Zhang, M.; Guo, J.; Guo, W.; Zhong, N.; Shen, H.; Wu, W.

10.1101/2020.01.15.908616 — microbiology — Posted on 2020-01-16

1950 Novel phylogeny of angiosperms inferred from whole-genome microsynteny analysis

Zhao, T.; Xue, J.; Kao, S.-m.; Li, Z.; Zwaenepoel, A.; Schranz, E.; Van de Peer, Y.

10.1101/2020.01.15.908376 — genomics — Posted on 2020-01-16

1951 Distinguishing the neural correlates of perceptual awareness and post-perceptual processing

Cohen, M. A.; Ortego, K.; Kyroudis, A.; Pitts, M.

10.1101/2020.01.15.908400 — neuroscience — Posted on 2020-01-16

1952 Spectral-power associations reflect amplitude modulation and within-frequency interactions on the sub-second timescale and cross-frequency interactions on the seconds timescale

Menceloglu, M.; Grabowecky, M.; Suzuki, S.

10.1101/2020.01.15.908103 — neuroscience — Posted on 2020-01-16

1953 Predictable Properties of Fitness Landscapes Induced by Adaptational Tradeoffs

Das, S. G.; Direito, S. O. L.; Waclaw, B.; Allen, R. J.; Krug, J.

10.1101/2020.01.15.908574 — evolutionary biology — Posted on 2020-01-16

1954 ipcoal: An interactive Python package for simulating and analyzing genealogies and sequences on a species tree or network

McKenzie, P. F.; Eaton, D. A. R.

10.1101/2020.01.15.908236 — bioinformatics — Posted on 2020-01-16

1955 Identifying Causal Variants by Fine Mapping Across Multiple Studies

LaPierre, N.; Taraszka, K.; Huang, H.; He, R.; Hormozdiari, F.; Eskin, E.

10.1101/2020.01.15.908517 — bioinformatics — Posted on 2020-01-16

1956 Microbial DNA on the move: sequencing based detection and analysis of transduced DNA in pure cultures and microbial communities

Kleiner, M.; Bushnell, B.; Sanderson, K. E.; Hooper, L. V.; Duerkop, B. A.

10.1101/2020.01.15.908442 — microbiology — Posted on 2020-01-16

1957 Deep Learning Modelling of Androgen Receptor Responses to Prostate Cancer Therapies

Snow, O.; Lallous, N.; Ester, M.; Cherkasov, A.

10.1101/2020.01.15.908384 — cancer biology — Posted on 2020-01-16

1958 EWS-FLI1 regulates and cooperates with core regulatory circuitry in Ewing sarcoma

Shi, X.; Zheng, Y.; Jiang, L.; Zhou, B.; Yang, W.; Li, L.; Ding, L.; Huang, M.; Gery, S.; Lin, D.-C.; Koeffler, H. P.

10.1101/2020.01.15.908475 — cancer biology — Posted on 2020-01-16

1959 mosaicFlye: Resolving long mosaic repeats using long error-prone reads

Bankevich, A.; Pevzner, P.

10.1101/2020.01.15.908285 — bioinformatics — Posted on 2020-01-16

1960 New complexities of SOS-induced untargeted mutagenesis in Escherichia coli as revealed by mutation accumulation and whole-genome sequencing

Niccum, B. A.; Coplen, C. P.; Lee, H.; Mohammed Ismail, W.; Tang, H.; Foster, P. L.

10.1101/2020.01.15.908301 — genetics — Posted on 2020-01-16

1961 Positive selection and fast turnover rate in tumor suppressor genes reveal how cetaceans resist cancer

Tejada Martinez, D.; de Magalhaes, J. P.; Opazo, J. C.

10.1101/2020.01.15.908244 — evolutionary biology — Posted on 2020-01-16

1962 Single-Cell Electrophysiological Measurements Reveal Bacterial Membrane Potential Dynamics during Extracellular Electron Transfer

Pirbadian, S.; Chavez, M. S.; El-Naggar, M. Y.

10.1101/2020.01.15.908145 — microbiology — Posted on 2020-01-16

1963 WNT and inflammatory signaling distinguish human Fallopian tube epithelial cell populations

Rose, I. M.; Bidarimath, M.; Webster, A.; Godwin, A. K.; Flesken-Nikitin, A.; Nikitin, A. Y.

10.1101/2020.01.15.908293 — cancer biology — Posted on 2020-01-16

1964 Expanding the utility of sequence comparisons using data from whole genomes

Gosselin, S. P.; Fullmer, M. S.; Feng, Y. P.; Gogarten, J. P.

10.1101/2020.01.15.908137 — bioinformatics — Posted on 2020-01-16

1965 The Mathematics Underlying Eeg Oscillations Propagation

Tozzi, A.; Bormashenko, E.; Jausovec, N.

10.1101/2020.01.15.908178 — neuroscience — Posted on 2020-01-16

1966 CluStrat: a structure informed clustering strategy for population stratification

Bose, A.; Burch, M. C.; Chowdhury, A.; Paschou, P.; Drineas, P.

10.1101/2020.01.15.908228 — genetics — Posted on 2020-01-16

1967 Alfalfa leaf curl virus is efficiently acquired by its aphid vector Aphis craccivora but inefficiently transmitted

Ryckebusch, F.; Peterschmitt, M.; Granier, M.; Sauvion, N.

10.1101/2020.01.15.908046 — ecology — Posted on 2020-01-16

1968 Urban warming inverse contribution on risk of dengue transmission in the southeastern North America

Simon, L. M.; Pinto-Ledezma, J. N.; Dunn, R. R.; Rangel, T. F.

10.1101/2020.01.15.908020 — ecology — Posted on 2020-01-16

1969 Macrofaunal Diversity and Community Structure of the DeSoto Canyon and Adjacent Slope

Shantharam, A. K.; Wei, C.-L.; Silva, M.; Baco, A. R.

10.1101/2020.01.15.908194 — ecology — Posted on 2020-01-16

1970 A scalable method for estimating the regional polygenicity of complex traits

Johnson, R. D.; Burch, K. S.; Hou, K.; Paciuc, M.; Pasaniuc, B.; Sankararaman, S.

10.1101/2020.01.15.908095 — genetics — Posted on 2020-01-16

1971 E. coli adhesion and biofilm formation on polydimethylsiloxane are independent of substrate stiffness

Arias, S. L.; Devorkin, J.; Civantos, A.; Allain, J. P.

10.1101/2020.01.15.907956 — bioengineering — Posted on 2020-01-16

1972 fMRI-guided white matter connectivity in fluid and crystallized cognitive abilities in healthy adults

Gazes, Y.; Sakhardande, J.; Mensing, A.; Razlighi, Q.; Ohkawa, A.; Pleshkevich, M.; Luo, L.; Habeck, C.

10.1101/2020.01.15.907782 — neuroscience — Posted on 2020-01-16

1973 Cytotoxic Activity Of A New Isoform L-Amino Acid Oxidase (Balt-LAAO-II) From Bothrops alternatus (Urutu) Snake Venom In Human Leukemic HL60 Cells

Heleno, M. A. G.; Carvalho, J. E.; Nowill, A.; Ponce-Soto, L. A.

10.1101/2020.01.15.907758 — pharmacology and toxicology — Posted on 2020-01-16

1974 Cotranslational Folding Stimulates Programmed Ribosomal Frameshifting in the Alphavirus Structural Polyprotein

Harrington, H. R.; Zimmer, M. H.; Chamness, L. M.; Nash, V.; Penn, W. D.; Miller, T. F.; Mukhopadhyay, S.; Schlebach, J. P.

10.1101/790444 — biochemistry — Posted on 2020-01-16

1975 BioSkills Guide: Development and National Validation of a Tool for Interpreting the Vision and Change Core Competencies

Clemmons, A.; Timbrook, J.; Herron, J.; Crowe, A.

10.1101/2020.01.11.902882 — scientific communication and education — Posted on 2020-01-16

1976 Fungal-bacterial interaction selects for quorum sensing mutants and a metabolic shift towards the production of natural antifungal compounds

Albarracin Orio, A. G.; Petras, D.; Tobares, R. A.; Aksenov, A.; Wang, M.; Juncosa, F.; Sayago, P.; Moyano, A. J.; Dorrestein, P. C.; Smania, A. M.; Ducasse, D.

10.1101/376590 — microbiology — Posted on 2020-01-16

1977 Stability Analysis of Delayed Age-structured Resource Consumer Model of Population Dynamics with Saturated Intake Rate

Akimenko, V. V.

10.1101/2020.01.10.901629 — ecology — Posted on 2020-01-16

1978 Comparative single-cell transcriptomics of complete insect nervous systems

Cocanougher, B. T.; Wittenbach, J. D.; Long, X.; Kohn, A. B.; Norekian, T. P.; Yan, J.; Colonell, J.; Masson, J.-B.; Truman, J. W.; Cardona, A.; Turaga, S.; Singer, R. H.; Moroz, L. L.; Zlatic, M.

10.1101/785931 — neuroscience — Posted on 2020-01-16

1979 Programmable low-cost DNA-based platform for viral RNA detection

Zhou, L.; Chandrasekaran, A. R.; Punnoose, J. A.; Bonenfant, G.; Charles, S.; Levchenko, O.; Badu, P.; Cavaliere, C.; Pager, C. T.; Halvorsen, K.

10.1101/2020.01.12.902452 — bioengineering — Posted on 2020-01-16

1980 Modular lipid nanoparticle platform technology for siRNA and lipophilic prodrug delivery

van der Meel, R.; Chen, S.; Zaifman, J.; Kulkarni, J. A.; Zhang, X. R. S.; Tam, Y. K.; Bally, M. B.; Schiffelers, R. M.; Ciufolini, M. A.; Cullis, P. R.; Tam, Y. Y. C.

10.1101/2020.01.16.907394 — bioengineering — Posted on 2020-01-16

1981 A behavioral polymorphism caused by a single gene inside a supergene

Merritt, J. R.; Grogan, K. E.; Zinzow-Kramer, W. M.; Sun, D.; Ortlund, E. A.; Yi, S. V.; Maney, D. L.

10.1101/2020.01.13.897637 — neuroscience — Posted on 2020-01-16

1982 Assessment of single cell RNA-seq statistical methods on microbiome data

Calgaro, M.; Romualdi, C.; Waldron, L. D.; Risso, D.; Vitulo, N.

10.1101/2020.01.15.907964 — bioinformatics — Posted on 2020-01-16

1983 Cold exposure distinctively modulates parathyroid and thyroid hormones in cold-acclimatized and non-acclimatized humans

Kovanicova, Z.; Kurdiova, T.; Balaz, M.; Stefanicka, P.; Varga, L.; Kulterer, O. C.; Betz, M. J.; Haug, A. R.; Burger, I. A.; Kiefer, F. W.; Wolfrum, C.; Ukropcova, B.; Ukropec, J.

10.1101/2020.01.16.906081 — physiology — Posted on 2020-01-16

1984 De novo learning versus adaptation of continuous control in a manual tracking task

Yang, C. S.; Cowan, N. J.; Haith, A. M.

10.1101/2020.01.15.906545 — neuroscience — Posted on 2020-01-16

1985 Dynamic Processing of Background Speech at the Cocktail Party: Evidence for Early Active Cortical Stream Segregation

Brodbeck, C.; Jiao, A.; Hong, L. E.; Simon, J. Z.

10.1101/866749 — neuroscience — Posted on 2020-01-16

1986 Simple and efficient measurement of transcription initiation and transcript levels with STRIPE-seq

Policastro, R. A.; Raborn, R. T.; Brendel, V. P.; Zentner, G. E.

10.1101/2020.01.16.905182 — genomics — Posted on 2020-01-16

1987 Estimating the rate of cell type degeneration from epigenetic sequencing of cell-free DNA

Caggiano, C.; Celona, B.; Garton, F.; Mefford, J. A.; Black, B.; Lomen-Hoerth, C.; Dahl, A.; Zaitlen, N.

10.1101/2020.01.15.907022 — genomics — Posted on 2020-01-16

1988 Using relative brain size to better understand trophic interactions and phenotypic plasticity of invasive lionfish (Pterois volitans)

Becker, M.

10.1101/2020.01.10.902049 — evolutionary biology — Posted on 2020-01-16

1989 Gatekeeper helix activates Golgi SM protein Sly1 and directly mediates close-range vesicle tethering

Duan, M.; Plemel, R. L.; Takenaka, T.; Lin, A.; Delgado, B. M.; Nattermann, U.; Nickerson, D. P.; Mima, J.; Miller, E. A.; Merz, A. J.

10.1101/2020.01.16.906719 — cell biology — Posted on 2020-01-16

1990 Transient Commensal Clonal Interactions Can Drive Tumor Metastasis

Naffar-Abu Amara, S.; Kuiken, H. J.; Selfors, L. M.; Butler, T.; Leung, M. L.; Leung, C. T.; Kuhn, E. P.; Kolarova, T. R.; Hage, C.; Ganesh, K.; Foster, R.; Rueda, B. R.; Aktipis, A.; Spellman, P. T.; Ince, T.; Navin, N.; Mills, G. B.; Bronson, R. T.; Brugge, J. S. S.

10.1101/2020.01.16.907071 — cancer biology — Posted on 2020-01-16

1991 Genetically encoded split luciferase biosensors to measure endosome disruption in real time in live cells

Kilchrist, K. V.; Tierney, J. W.; Duvall, C. L.

10.1101/2020.01.16.906180 — bioengineering — Posted on 2020-01-16

1992 A simple model for learning in volatile environments

Piray, P.; Daw, N. D.

10.1101/701466 — neuroscience — Posted on 2020-01-16

1993 Functional interaction between Fanconi anemia and mTOR pathways during stalled replication fork recovery

Nolan, M.; Knudson, K.; Holz, M. K.; Chaudhury, I.

10.1101/2020.01.16.899211 — molecular biology — Posted on 2020-01-16

1994 The structure and global distribution of the endoplasmic reticulum network is actively regulated by lysosomes

Lu, M.; van Tartwijk, F. W.; Lin, J. Q.; Nijenhuis, W.; Parutto, P.; Fantham, M.; Christensen, C. N.; Avezov, E.; Holt, C. E.; Tunnacliffe, A.; Holcman, D.; Kapitein, L.; Kaminski Schierle, G.; Kaminski, C. F.

10.1101/2020.01.15.907444 — cell biology — Posted on 2020-01-16

1995 Improvement of phycocyanobilin synthesis for genetically encoded phytochrome-based optogenetics.

Uda, Y.; Miura, H.; Goto, Y.; Aoki, K.

10.1101/2020.01.15.908343 — synthetic biology — Posted on 2020-01-16

1996 Modular and distinct PlexinA4/Farp2/Rac1 signaling controls dendrite morphogenesis

Danelon, V.; Goldner, R.; Martinez, E.; Gokhman, I.; Wang, K.; Yaron, A.; Tran, T. S.

10.1101/2020.01.15.908434 — neuroscience — Posted on 2020-01-16

1997 Development of Microstructural and Morphological Cortical Profiles in the Neonatal Brain

Fenchel, D.; Dimitrova, R.; Seidlitz, J.; Robinson, E. C.; Batalle, D.; Hutter, J.; Christiaens, D.; Pietsch, M.; Brandon, J.; Hughes, E. J.; Allsop, J.; O'Keeffe, C.; Price, A. N.; Cordero-Grande, L.; Schuh, A.; Makropoulos, A.; Passerat-Palmbach, J.; Bozek, J.; Rueckert, D.; Hajnal, J. V.; Raznahan, A.; McAlonan, G.; Edwards, A. D.; O'Muircheartaigh, J.

10.1101/2020.01.14.906206 — neuroscience — Posted on 2020-01-16

1998 A comparative 'omics approach to candidate pathogenicity factor discovery in the brain-eating amoeba Naegleria fowleri

Herman, E. K.; Greninger, A. L.; van der Geizen, M.; Ginger, M. L.; Ramirez-Macias, I.; Miller, H. C.; Morgan, M. J.; Tsaousis, A. D.; Velle, K.; Vargova, R.; Najle, S. R.; MacIntyre, G.; Mueller, N.; Wittwer, M.; Zysset-Burri, D. C.; Elias, M.; Slamovits, C. H.; Weirauch, M.; Fritz-Laylin, L.; Marciano-Cabral, F.; Puzon, G. J.; Walsh, T.; Chiu, C. Y.; Dacks, J. B.

10.1101/2020.01.16.908186 — microbiology — Posted on 2020-01-16

1999 Exons as units of phenotypic impact for truncating mutations in autism

Chiang, A. H.; Chang, J.; Wang, J.; Vitkup, D.

10.1101/270850 — genetics — Posted on 2020-01-16

2000 Bioluminescence dynamics in single germinating bacterial spores reveal metabolic heterogeneity

Frentz, Z.; Dworkin, J.

10.1101/2020.01.14.906875 — biophysics — Posted on 2020-01-16

2001 Long weekend sleep is linked to stronger academic performance in male but not female pharmacy students

Leak, R. K.; Weiner, S. L.; Chandwani, M. N.; Rhodes, D. C.

10.1101/2020.01.15.907907 — scientific communication and education — Posted on 2020-01-16

2002 Identification of miRNA signatures for kidney renal clear cell carcinoma using the tensor-decomposition method

Ng, K.-L.; Taguchi, Y.-h.

10.1101/849679 — bioinformatics — Posted on 2020-01-16

2003 Suprathreshold contrast response in normal and anomalous trichromats

Knoblauch, K.; Marsh-Armstrong, B.; Werner, J. S.

10.1101/788331 — neuroscience — Posted on 2020-01-16

2004 C subunit of the ATP synthase is an amyloidogenic channel-forming peptide: possible implications in mitochondrial pathogenesis

Amodeo, G. F.; Lee, B. Y.; Krilyuk, N.; Filice, C. T.; Valyuk, D.; Otzen, D.; Noskov, S.; Leonenko, Z.; Pavlov, E. V.

10.1101/2020.01.16.908335 — biophysics — Posted on 2020-01-16

2005 Characterization of eyes, photoreceptors and opsins in developmental stages of the chaetognath Spadella cephaloptera

Wollesen, T.; Rodriguez Monje, S. V.; Oel, A. P.; Arendt, D.

10.1101/871111 — zoology — Posted on 2020-01-16

2006 Is there a universal glycan alphabet?

Srivastava, J.; Sunthar, P.; Balaji, P. V.

10.1101/2020.01.15.908491 — genomics — Posted on 2020-01-16

2007 Impact of nanoscale hindrances on the relationship between lipid packing and diffusion in model membranes

Beckers, D.; Urbancic, D.; Sezgin, E.

10.1101/2020.01.16.907816 — biophysics — Posted on 2020-01-16

2008 Optimized single molecule fluorescence sheds light on elusive enzymatic mechanisms

Mansson, A.; Usaj, M.; Moretto, L.; Vemula, V.; Salhotra, A.

10.1101/2020.01.16.908947 — biophysics — Posted on 2020-01-16

2009 vRNA-vRNA interactions in influenza A virus HA vRNA packaging

Miyamoto, S.; Muramoto, Y.; Shindo, K.; Fujita, Y.; Morikawa, T.; Tamura, R.; Gilmore, J. L.; Nakano, M.; Noda, T.

10.1101/2020.01.15.907295 — microbiology — Posted on 2020-01-16

2010 Crystal structure of the giant panda MHC class I complex: first insights into the viral peptide presentation profile in the bear family

Yuan, H.; Ma, L.; Zhang, L.; Li, X.; Xia, C.

10.1101/2020.01.15.908608 — immunology — Posted on 2020-01-16

2011 What is the test-retest reliability of common task-fMRI measures? Newempirical evidence and a meta-analysis

Elliott, M. L.; Knodt, A. R.; Ireland, D.; Morris, M. L.; Polton, R.; Ramrakha, S.; Sison, M. L.; Moffitt, T. E.; Caspi, A.; Hariri, A.

10.1101/681700 — neuroscience — Posted on 2020-01-16

2012 Gut-associated bacteria invade the midgut epithelium of Aedes aegypti and stimulate innate immunity and suppress Zika virus infection in cells.

Hegde, S.; Voronin, D.; Casas-Sanchez, A.; Saldana, M. A.; Heinz, E.; Acosta-Serrano, A.; Popov, V. L.; Chopra, A. K.; Hughes, G. L.

10.1101/866897 — microbiology — Posted on 2020-01-16

2013 Computational principles of neural adaptation for binaural signal integration

Oess, T.; Ernst, M. O.; Neumann, H.

10.1101/863258 — neuroscience — Posted on 2020-01-16

2014 A 19-isolate reference-quality global pangenome for the fungal wheat pathogen Zymoseptoria tritici

Badet, T.; Oggenfuss, U.; Abraham, L.; McDonald, B. A.; Croll, D.

10.1101/803098 — genomics — Posted on 2020-01-16

2015 Continent-wide effects of urbanization on bird and mammal genetic diversity

Schmidt, C.; Domaratzki, M.; Bowman, J.; Kinnunen, R. P.; Garroway, C. J.

10.1101/733170 — evolutionary biology — Posted on 2020-01-16

2016 A Unique Mouse Model of Early-Life Exercise Enables Hippocampal Memory and Synaptic Plasticity

Ivy, A. S.; Yu, T.; Kramar, E.; Parievsky, S.; Sohn, F.; Vu, T. L.

10.1101/699603 — neuroscience — Posted on 2020-01-16

2017 A simple model for learning in volatile environments

Piray, P.; Daw, N. D.

10.1101/701466 — neuroscience — Posted on 2020-01-16

2018 Log Transformation Improves Dating of Phylogenies

Mai, U.; Mirarab, S.

10.1101/2019.12.20.885582 — evolutionary biology — Posted on 2020-01-16

2019 Maximum CO2 diffusion inside leaves is limited by the scaling of cell size and genome size

Theroux-Rancourt, G.; Roddy, A. B.; Earles, J. M.; Gilbert, M. E.; Zwieniecki, M. A.; Boyce, C. K.; Tholen, D.; McElrone, A. J.; Simonin, K. A.; Brodersen, C. R.

10.1101/2020.01.16.904458 — plant biology — Posted on 2020-01-16

2020 An overview of the quality assurance and quality control of magnetic resonance imaging data for the Ontario Neurodegenerative Disease Research Initiative (ONDRI): pipeline development and neuroinformatics

Scott, C. J. M.; Arnott, S. R.; Chemparathy, A.; Dong, F.; Solovey, I.; Gee, T.; Schmah, T.; Chavez, S.; Lobaugh, N.; Nanayakkara, N.; Liang, S.; Zamyadi, M.; Ozzoude, M.; Holmes, M. F.; Szilagyi, G. M.; Ramirez, J.; Symons, S.; Black, S. E.; Bartha, R.; Strother, S.; The ONDRI investigators,

10.1101/2020.01.10.896415 — neuroscience — Posted on 2020-01-16

2021 Neural measures of subsequent memory reflect endogenous variability in cognitive function

Weidemann, C. T.; Kahana, M. J.

10.1101/576173 — neuroscience — Posted on 2020-01-16

2022 Remodeling gut microbiota by Streptococcus thermophilus 19 attenuates inflammation in septic mice

Han, F.; Zhang, Y.; Yang, X.; Fang, Z.; Han, S.; Li, X.; Cai, W.; Xiao, D.; Liu, J.; Zhang, W.; Wu, G.; Hu, D.

10.1101/543967 — microbiology — Posted on 2020-01-16

2023 Context-specific functions of Notch in Drosophila blood cell progenitors

Blanco-Obregon, D. M.; Katz, M. J.; Durrieu, L.; Gandara, L.; Wappner, P.

10.1101/682658 — developmental biology — Posted on 2020-01-16

2024 Origin of perseveration in the trade-off between reward and complexity

Gershman, S. J.

10.1101/2020.01.16.903476 — animal behavior and cognition — Posted on 2020-01-16

2025 Disentangling the effects of sampling scale and size on the shape of species abundance distributions

Lima, R. A. F.; Conde, P. A.; Banks-Leite, C.; Campos, R. C.; Hernandez, M. I. M.; Rodrigues, R. R.; Prado, P. I.

10.1101/2020.01.15.900258 — ecology — Posted on 2020-01-16

2026 IRESbase: a Comprehensive Database of Experimentally Validated Internal Ribosome Entry Sites

Zhao, J.; Li, Y.; Wang, C.; Zhang, H.; Zhang, H.; Jiang, B.; Guo, X.; Song, X.

10.1101/2020.01.15.894592 — bioinformatics — Posted on 2020-01-16

2027 Integrating Lung Tissue and Lavage Proteomes Reveals Unique Pathways in Allergen-Challenged Mice

Halayko, A. J.; Mahood, T. H.; Pascoe, C. D.; Jha, A.; Basu, S.; Ezatti, P.; Spicer, V.; Mookherjee, N.

10.1101/2020.01.14.905737 — systems biology — Posted on 2020-01-16

2028 Improved bacterial recombineering by parallelized protein discovery

Wannier, T. M.; Nyerges, A.; Kuchwara, H.; Czikkely, M.; Balogh, D.; Filsinger, G. T.; Borders, N. C.; Gregg, C. J.; Lajoie, M. J.; Rios, X.; Pal, C.; Church, G. M.

10.1101/2020.01.14.906594 — microbiology — Posted on 2020-01-16

2029 Crowdsourcing digital health measures to predict Parkinson's disease severity: the Parkinson's Disease Digital Biomarker DREAM Challenge

Sieberts, S. K.; Schaff, J.; Duda, M.; Pataki, B. A.; Sun, M.; Snyder, P.; Daneault, J.-F.; Parisi, F.; Costante, G.; Rubin, U.; Banda, P.; Chae, Y.; Neto, E. C.; Dorsey, R.; Aydın, Z.; Chen, A.; Elo, L. L.; Espino, C.; Glaab, E.; Goan, E.; Golabchi, F. N.; Görmez, Y.; Jaakkola, M. K.; Jonnagaddala, J.; KLEn, R.; Li, D.; McDaniel, C.; Perrin, D.; Rad, N. M.; Rainaldi, E.; Sapienza, S.; Schwab, P.; Shokhirev, N.; Venäläinen, M. S.; Vergara-Diaz, G.; Zhang, Y.; Parkinson's Disease Digital Biomarker Challenge Consortium, ; Wang, Y.; Guan, Y.; Brunner, D.; Bonato, P.; Mangravite, L. M.; Omberg

10.1101/2020.01.13.904722 — bioengineering — Posted on 2020-01-16

2030 The Nonequilibrium Mechanism of Noise Enhancer synergizing with Activator in HIV Latency Reactivation

Guo, X.; Tang, T.; Duan, M.; Zhang, L.; Ge, H.

10.1101/2020.01.14.905653 — systems biology — Posted on 2020-01-16

2031 Dietary Amino Acids Impact LRRK2-induced Neurodegeneration in Parkinson's Disease Models

Chittoor-Vinod, V. G.; Villalobos-Cantor, S.; Roshak, H.; Shea, K.; Martin, I.

10.1101/2020.01.13.905471 — neuroscience — Posted on 2020-01-16

2032 Nivolumab and Ipilimumab in Metastatic Melanoma Are Associated with Distinct Immune Landscape Changes and Response-Associated Immunophenotypes

Woods, D. M.; Laino, A. S.; Winters, A. F.; Alexandre, J. M.; Rao, V.; Adavani, S. S.; Weber, J. S.; Chattopadhyay, P. K.

10.1101/2020.01.13.905430 — immunology — Posted on 2020-01-16

2033 Efficient Coding in the Economics of Human Brain Connectomics

Zhou, D.; Lynn, C. W.; Cui, Z.; Ciric, R.; Baum, G. L.; Moore, T. M.; Roalf, D. R.; Detre, J. A.; Gur, R. C.; Gur, R. E.; Satterthwaite, T. D.; Bassett, D. S.

10.1101/2020.01.14.906842 — neuroscience — Posted on 2020-01-16

2034 A young age of subspecific divergence in the desert locust Schistocerca gregaria inferred by ABC Random Forest

Chapuis, M.-P.; Raynal, L.; Plantamp, C.; Meynard, C. N.; Blondin, L.; Marin, J.-M.; Estoup, A.

10.1101/671867 — evolutionary biology — Posted on 2020-01-16

2035 Regulation of BMP Signaling by O-GlcNAcylation

Moulton, M. J.; Humphreys, G. B.; Kim, A.; Letsou, A.

10.1101/784629 — developmental biology — Posted on 2020-01-16

2036 Active inference under visuo-proprioceptive conflict: Simulation and empirical results

Limanowski, J.; Friston, K.

10.1101/795419 — neuroscience — Posted on 2020-01-16

2037 Two-step mechanism of J-domain action in driving Hsp70 function

Tomiczek, B.; Delewski, W.; Nierzwicki, L.; Stolarska, M.; Grochowina, I.; Schilke, B.; Dutkiewicz, R.; Uzarska, M. A.; Ciesielski, S. J.; Czub, J.; Craig, E. A.; Marszalek, J.

10.1101/2020.01.13.901538 — molecular biology — Posted on 2020-01-16

2038 scTPA: A web tool for single-cell transcriptome analysis of pathway activation signatures

Zhang, Y.; Zhang, Y.; Hu, J.; Zhang, J.; Guo, F.; Zhou, M.; Zhang, G.; Yu, F.; Su, J.

10.1101/2020.01.15.907592 — genomics — Posted on 2020-01-16

2039 Genome wide sequencing provides evidence of adaptation to heterogeneous environments for the ancient relictual Circaeaster agrestis (Circaeasteraceae, Ranunculales)

Zhang, X.; Sun, Y.; Landis, J. B.; Zhang, J.; Yang, L.; Lin, N.; Zhang, H.; Guo, R.; Li, L.; Zhang, Y.; Deng, T.; Sun, H.; Wang, H.

10.1101/2020.01.14.902643 — genomics — Posted on 2020-01-16

2040 Status of aquatic and riparian biodiversity in artificial lake ecosystems with and without management for recreational fisheries: Implications for conservation

Nikolaus, R.; Schafft, M.; Maday, A.; Klefoth, T.; Wolter, C.; Arlinghaus, R.

10.1101/667493 — ecology — Posted on 2020-01-16

2041 REMoDNaV: Robust Eye Movement Detection for Natural Viewing

Dar, A. H.; Wagner, A. S.; Hanke, M.

10.1101/619254 — bioinformatics — Posted on 2020-01-16

2042 Maximization of non-nitrogenous metabolite production in E. coli using population systems biology

Rajagopal, S.; Ghatak, A.; Mookherjee, D.; Hmar, R. V.; Shanbhag, A. P.; Venkataraman, J.; Katagihallimath, N.; S, R. K.; Datta, S.

10.1101/2019.12.27.888545 — bioengineering — Posted on 2020-01-16

2043 Rapid evolution of learning and reproduction in natural populations of Drosophila melanogaster

Behrman, E. L.; Kawecki, T. J.; Schmidt, P.

10.1101/288696 — evolutionary biology — Posted on 2020-01-16

2044 Discovery of biased orientations of human DNA motif sequences affecting enhancer-promoter interactions and transcription of genes

Osato, N.

10.1101/290825 — bioinformatics — Posted on 2020-01-16

2045 Fusobacterium nucleatum host cell binding and invasion induces IL-8 and CXCL1 secretion that drives colorectal cancer cell migration

Casasanta, M. A.; Yoo, C. C.; Udayasuryan, B.; Sanders, B. E.; Umana, A.; Zhang, Y.; Peng, H.; Duncan, A. J.; Wang, Y.; Li, L.; Verbridge, S. S.; Slade, D. J.

10.1101/2020.01.15.907931 — cancer biology — Posted on 2020-01-16

2046 Age-Stage, Two-Sex Life Table of the Menochilus sexmaculatus (Coccinellidae: Coleoptera) Feeding on Different Aphid Species

Abbas, K.; Zaib, M. S.; Zakria, M.; Hani, U.-e.; Zaka, S. M.; Ain, N.-u.

10.1101/2020.01.15.907576 — zoology — Posted on 2020-01-15

2047 Post-transcriptional modulation of the SigF regulon in Mycobacterium smegmatis by the PhoH2 toxin-antitoxin.

Andrews, E. S.; Rzoska-Smith, E.; Arcus, V. L.

10.1101/2020.01.15.907535 — molecular biology — Posted on 2020-01-15

2048 Pathogens, endosymbionts, and blood-meal sources of host-seeking ticks in the fast-changing Maasai Mara wildlife ecosystem

Oundo, J. W.; Villinger, J.; Jeneby, M.; Ong'amo, G.; Otiende, M. Y.; Makhulu, E. E.; Musa, A. A.; Ouso, D. O.; Wambua, L.

10.1101/2020.01.15.907568 — molecular biology — Posted on 2020-01-15

2049 Downregulation of both mismatch repair and non-homologous end-joining pathways in hypoxic brain tumour cell lines

Cowman, S.; Pizer, B.; See, V.

10.1101/2020.01.15.907584 — cancer biology — Posted on 2020-01-15

2050 The distribution of functional N-cycle related genes and nitrogen in soil profiles fertilized with mineral and organic N fertilizer

Zilio, M.; Motta, S.; Tambone, F.; Scaglia, B.; Boccasile, G.; Squartini, A.; Adani, f.

10.1101/2020.01.15.907543 — ecology — Posted on 2020-01-15

2051 Compensatory mutation can drive gene regulatory network evolution

Wang, Y.; Richards, M.; Dorus, S.; Priest, N. K.; Bryson, J. J.

10.1101/2019.12.18.881276 — systems biology — Posted on 2020-01-15

2052 Integrative analysis identifies candidate tumor microenvironment and intracellular signaling pathways that define tumor heterogeneity in NF1

Banerjee, J.; Allaway, R. J.; Taroni, J. N.; Baker, A.; Zhang, X.; Moon, C. I.; Blakeley, J. O.; Guinney, J.; Hirbe, A.; Greene, C. S.; Gosline, S. J.

10.1101/2020.01.13.904771 — systems biology — Posted on 2020-01-15

2053 Adopting tipping-point theory to patient transcriptomes unravels gene regulatory network dynamics

Yang, X. H.; Wang, Z.; Feliciano, A.; Griggs, D.; Tang, F.; An, Q.; Cunningham, J.

10.1101/668442 — systems biology — Posted on 2020-01-15

2054 The conserved regulatory basis of mRNA contributions to the early Drosophila embryo differs between the maternal and zygotic genomes

Omura, C. S.; Lott, S. E.

10.1101/769638 — evolutionary biology — Posted on 2020-01-15

2055 The gamma-Protocadherins regulate the survival of GABAergic interneurons during developmentally-regulated cell death.

Carriere, C. H.; Sing, A. D.; Wang, W. X.; Jones, B. E.; Yee, Y.; Marocha, J.; Maganti, H.; Ellegood, J.; Awofala, L.; Aziz, A.; Lerch, J. P.; Lefebvre, J. L.

10.1101/2020.01.15.908087 — neuroscience — Posted on 2020-01-15

2056 Specialization for cell-free or cell-to-cell spread of BAC-cloned HCMV strains is determined by factors beyond the UL128-131 and RL13 loci.

Schultz, E. P.; Lanchy, J.-M.; Day, L. Z.; Yu, Q.; Peterson, C.; Preece, J.; Ryckman, B.

10.1101/760611 — microbiology — Posted on 2020-01-15

2057 Assessing neurophysiological changes associated with combined transcranial direct current stimulation and cognitive emotional training for treatment-resistant depression

Nikolin, S.; Martin, D.; Loo, C.; Iacoviello, B.; Boonstra, T.

10.1101/688317 — neuroscience — Posted on 2020-01-15

2058 Dicer- and BSC-dependent miRNAs during murine anagen hair follicle development

Lisse, T. S.; Vishlaghi, N.

10.1101/2020.01.12.903567 — molecular biology — Posted on 2020-01-15

2059 CoproID predicts the source of coprolites and paleofeces using microbiome composition and host DNA content

Borry, M.; Cordova, B.; Perri, A.; Wibowo, M. C.; Honap, T.; Ko, W. T. J.; Yu, J.; Britton, K.; Flink, L. G.; Power, R. C.; Stuijts, I.; Garcia, D. S.; Hofman, C. A.; Hagan, R. W.; Kagone, T. S.; Meda, N.; Carabin, H.; Jacobson, D.; Reinhard, K.; Lewis, C. M.; Kostic, A.; Jeong, C.; Herbig, A.; Huebner, A.; Warinner, C.

10.1101/871533 — microbiology — Posted on 2020-01-15

2060 Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila

Cho, B.; Yoon, S.-H.; Lee, D.; Koranteng, F.; Tattikota, S. G.; Cha, N.; Shin, M.; Do, H.; Hu, Y.; Oh, S. Y.; Moon, S. J.; Perrimon, N.; Nam, J.-W.; Shim, J.

10.1101/2020.01.15.908350 — developmental biology — Posted on 2020-01-15

2061 Colorectal cancer marker identification using the aging immune system-related blood cell DNA methylome

Quan, Y.; Liang, F.; Wu, D.; Zhu, Y.; Chen, Y.; Wu, A.; Tang, D.; Huang, B.; Xu, R.; Lyu, Z.; Yan, Q.; Ning, Z.; Li, Y.; Xiong, J.

10.1101/2020.01.13.905299 — cancer biology — Posted on 2020-01-15

2062 Theory of transcription bursting: Stochasticity in the transcription rates

Murugan, R.

10.1101/2019.12.18.880435 — biophysics — Posted on 2020-01-15

2063 Gapless assembly of maize chromosomes using long read technologies

Liu, J.; Seetharam, A. S.; Chougule, K.; Ou, S.; Swentowsky, K. W.; Gent, J. I.; Llaca, V.; Woodhouse, M.; Manchanda, N.; Presting, G. G.; Kudrna, D.; Alabady, M.; Hirsch, C.; Fengler, K.; Ware, D.; Michael, T.; Hufford, M.; Dawe, K.

10.1101/2020.01.14.906230 — bioinformatics — Posted on 2020-01-15

2064 Structural Analysis of the PATZ1 BTB domain homodimer

Piepoli, S.; Alt, A. O.; Atilgan, C.; Mancini, E. J.; Erman, B.

10.1101/2020.01.13.903898 — molecular biology — Posted on 2020-01-15

2065 Dynamic metabolic reprogramming in dendritic cells: an early response to influenza infection that is essential for effector function

Rezinciuc, S.; Bezavada, L.; Bahadoran, A.; Duan, S.; Wang, R.; Ferrer, D. L.; Finklestein, D.; Green, D. R.; Tolic, L. P.; Thomas, P. G.; Smallwood, H.

10.1101/2020.01.14.906826 — immunology — Posted on 2020-01-15

2066 Stretching DNA to twice the normal length with single-molecule hydrodynamic trapping

Jiang, Y.; Feldman, T.; Bakx, J. A. M.; Yang, D.; Wong, W. P.

10.1101/801464 — biophysics — Posted on 2020-01-15

2067 Bioluminescence dynamics in single germinating bacterial spores reveal metabolic heterogeneity

Frentz, Z.; Dworkin, J.

10.1101/2020.01.14.906875 — biophysics — Posted on 2020-01-15

2068 Distinct structure-function relationships across cortical regions and connectivity scales in the rat brain

Straathof, M.; Sinke, M. R. T.; Roelofs, T. J. M.; Blezer, E. L. A.; Sarabdjitsingh, R. A.; van der Toorn, A.; Schmitt, O.; Otte, W. M.; Dijkhuizen, R. M.

10.1101/742833 — neuroscience — Posted on 2020-01-15

2069 Surface association induces cytotoxic alkyl-quinolones in Pseudomonas aeruginosa

Vrla, G. D.; Esposito, M.; Zhang, C.; Kang, Y.; Seyedsayamdost, M. R.; Gitai, Z.

10.1101/773291 — microbiology — Posted on 2020-01-15

2070 Uncovering the hidden antibiotic potential of Cannabis

Farha, M. A.; El-Halfawy, O. M.; Gale, R. T.; MacNair, C. R.; Carfrae, L. A.; Zhang, X.; Jentsch, N. G.; Magolan, J.; Brown, E. D.

10.1101/833392 — microbiology — Posted on 2020-01-15

2071 A multivalent DNA vaccine against group A human rotavirus: An in silico investigation

Dutta, K.

10.1101/2020.01.13.903781 — immunology — Posted on 2020-01-15

2072 Distinctive epigenomic alterations in NF1-deficient cutaneous and plexiform neurofibromas drive differential MKK/P38 signaling

Grit, J. L.; Johnson, B. K.; Dischinger, P. S.; Essenburg, C. J.; Campbell, S.; Pollard, K.; Pratilas, C.; Triche, T. J.; Graveel, C. R.; Steensma, M. R.

10.1101/833467 — genomics — Posted on 2020-01-15

2073 The adaptive potential of the middle domain of yeast Hsp90

Cote-Hammarlof, P. A.; Fragata, I.; Flynn, J.; Zeldovich, K. B.; Bank, C.; Bolon, D. N. A.

10.1101/832022 — evolutionary biology — Posted on 2020-01-15

2074 What can we learn from over 100,000 Escherichia coli genomes?

Abram, K. Z.; Udaondo, Z.; Bleker, C.; Wanchai, V.; Wassenaar, T. M.; Robeson, M. S.; Ussery, D. W.

10.1101/708131 — genomics — Posted on 2020-01-15

2075 Representation of k-mer sets using spectrum-preserving string sets

Rahman, A.; Medvedev, P.

10.1101/2020.01.07.896928 — bioinformatics — Posted on 2020-01-15

2076 Inhibiting Mycobacterium tuberculosis CoaBC by targeting a new allosteric site.

Mendes, V.; Green, S. R.; Evans, J. C.; Hess, J.; Blaszczyk, M.; Spry, C.; Bryant, O.; Cory-Wright, J.; Chan, D. S.-H.; Torres, P. H. M.; Wang, Z.; O'Neill, S.; Damerow, S.; Post, J.; Bayliss, T.; Lynch, S. L.; Coyne, A. G.; Ray, P. C.; Abell, C.; Rhee, K. Y.; Boshoff, H. I. M.; Barry, C. E.; Mizrahi, V.; Wyatt, P. G.; Blundell, T. L.

10.1101/870154 — biochemistry — Posted on 2020-01-15

2077 Improving the coverage of credible sets in Bayesian genetic fine-mapping

Hutchinson, A.; Watson, H.; Wallace, C.

10.1101/781062 — genetics — Posted on 2020-01-15

2078 Genetic and bioinformatic approaches to characterize ethanol teratogenesis

Sidik, A.; Dixon, G. B.; Kirby, H. G.; Eberhart, J. K.

10.1101/805556 — developmental biology — Posted on 2020-01-15

2079 Functional innovation in the evolution of the calcium-dependent system of the eukaryotic endoplasmic reticulum

Schäffer, D. E.; Iyer, L. M.; Burroughs, A. M.; Aravind, L.

10.1101/716472 — bioinformatics — Posted on 2020-01-15

2080 A reference map of the human proinsulin biosynthetic interaction network

Tran, D. T.; Pottekat, A.; Mir, S. A.; Jang, I.; Loguercio, S.; Campos, A. R.; Lahmy, R.; Liu, M.; Arvan, P.; Balch, W. E.; Kaufman, R. J.; Itkin-Ansari, P.

10.1101/699132 — biochemistry — Posted on 2020-01-15

2081 Functional organization of three-dimensional orientation encoding within the visual cortex

Rideaux, R.; Welchman, A. E.

10.1101/2020.01.15.907683 — neuroscience — Posted on 2020-01-15

2082 Temporal dynamics of GABA and Glx in the visual cortex

Rideaux, R.

10.1101/2020.01.15.907659 — neuroscience — Posted on 2020-01-15

2083 The medial temporal lobe is critical for spatial relational attention

Ruiz, N. A.; Meager, M. R.; Agarwal, S.; Aly, M.

10.1101/765222 — neuroscience — Posted on 2020-01-15

2084 A doublecortin-domain protein of Toxoplasma and its orthologues bind to and modify the structure and organization of tubulin polymers

Leung, J. M.; Nagayasu, E.; Hwang, Y.-C.; Liu, J.; Pierce, P.; Phan, I. Q.; Prentice, R. A.; Murray, J. M.; Hu, K.

10.1101/623140 — cell biology — Posted on 2020-01-15

2085 Genomic analyses provide insights into peach local adaptation and responses to climate change

Li, Y.; Cao, K.; Li, N.; Fang, W.; Chen, C.; Wang, X.; Zeng, X.; Guo, J.; Zhang, S.; Wang, Q.; Ding, T.; Wang, J.; Wang, J.; Liu, K.; Guo, W.; Arus, P.; Huang, S.; Fei, Z.; Wang, L.

10.1101/2020.01.15.907709 — genomics — Posted on 2020-01-15

2086 A minimum reporting standard for multiple sequence alignments

Wong, T. K.; Kalyaanamoorthy, S.; Meusemann, K.; Yeates, D. K.; Misof, B.; Jermiin, L. S.

10.1101/2020.01.15.907733 — bioinformatics — Posted on 2020-01-15

2087 RNA-dependent structures of the RNA-binding loop in the flavivirus NS3 helicase

Davidson, R. B.; Hendrix, J.; Geiss, B. J.; McCullagh, M.

10.1101/2020.01.15.907725 — biophysics — Posted on 2020-01-15

2088 Statistical analysis of no observed effect concentrations or levels in eco-toxicological assays with overdispersed count endpoints

Hothorn, L. A.; Kluxen, F. M.

10.1101/2020.01.15.907881 — pharmacology and toxicology — Posted on 2020-01-15

2089 A Connectivity-based Psychometric Prediction Framework for Brain-behavior Relationship Studies

Wu, J.; Eickhoff, S. B.; Hoffstaedter, F.; Patil, K. R.; Schwender, H.; Genon, S.

10.1101/2020.01.15.907642 — neuroscience — Posted on 2020-01-15

2090 Protrudin functions as a scaffold in the endoplasmic reticulum to support axon regeneration in the adult central nervous system

Petrova, V.; Pearson, C. S.; Tribble, J. R.; Solano, A. G.; Reid, E.; Geller, H. M.; Williams, P. A.; Eva, R.; Fawcett, J. W.

10.1101/2020.01.15.907550 — neuroscience — Posted on 2020-01-15

2091 Impact of b-value on estimates of apparent fibre density

Genc, S.; Tax, C. M. W.; Raven, E. P.; Chamberland, M.; Parker, G. D.; Jones, D. K.

10.1101/2020.01.15.905802 — neuroscience — Posted on 2020-01-15

2092 Role of astrogial Connexin 43 in pneumococcal meningitis and pneumolysin cytotoxicity

Bello, C.; Smail, Y.; Sainte-Rose, V.; Podglajen, I.; Gilbert, A.; Oliveira Moreira, V.; Chretien, F.; Cohen-Salmon, M.; Tran Van Nhieu, G.

10.1101/2020.01.15.907923 — microbiology — Posted on 2020-01-15

2093 Bayesian non-parametric clustering of single-cell mutation profiles

Borgsmueller, N.; Bonet, J.; Marass, F.; Gonzalez-Perez, A.; Lopez-Bigas, N.; Beerenwinkel, N.

10.1101/2020.01.15.907345 — bioinformatics — Posted on 2020-01-15

2094 Human CTC1 primarily functions in telomere maintenance/protection and promotes CHK1 phosphorylation in response to global replication stress

Ackerson, S. M.; Gable, C. I.; Stewart, J. A.

10.1101/2020.01.15.906891 — molecular biology — Posted on 2020-01-15

2095 The WD and linker domains of ATG16L1 required for non canonical autophagy limit lethal influenza A virus infection at epithelial surfaces.

Wang, Y.; Zhang, W.; Jefferson, M.; Sharma, P.; Bone, B.; Kipar, A.; Coombes, J. L.; Pearson, T.; Mann, A.; Zhekova, A.; Bao, Y.; Tripp, R. A.; Carding, S. R.; Mayer, U.; Powell, P. P.; Stewart, J. P.; Wileman, T.

10.1101/2020.01.15.907873 — microbiology — Posted on 2020-01-15

2096 Individual yeast cells signal at different levels but each with good precision

Andrews, S. S.; Brent, R.

10.1101/2020.01.15.906867 — systems biology — Posted on 2020-01-15

2097 More filtering on SNP calling does not remove evidence of inter-nucleus recombination in dikaryotic arbuscular mycorrhizal fungi

Chen, E.; Mathieu, S.; Hoffrichter, A.; Ropars, J.; Dreissig, S.; Fuchs, J.; Brachmann, A.; Corradi, N.

10.1101/2020.01.15.906412 — genomics — Posted on 2020-01-15

2098 The structure and global distribution of the endoplasmic reticulum network is actively regulated by lysosomes

Lu, M.; van Tartwijk, F. M.; Lin, Q.; Nijenhuis, W.; Parutto, P.; Fantham, M.; Christensen, C. N.; Avezov, E.; Holt, C. E.; Tunnacliffe, A.; Holcman, D.; Kapitein, L.; Kaminski Schierle, G.; Kaminski, C. F.

10.1101/2020.01.15.907444 — cell biology — Posted on 2020-01-15

2099 Characterization of Prenylated C-terminal Peptides Using a Novel Capture Technique Coupled with LCMS

Wilkins, J. A.; Kaasik, K.; Chalkley, R. J.; Burlingame, A.

10.1101/2020.01.15.908152 — biochemistry — Posted on 2020-01-15

2100 Diversified Learning Environment Alleviates Learning Impairment Caused by Contextual Stress

Gong, C.; Zhang, M.; Zhang, Y.; Liu, X.; Liu, P.; Zhou, Y.; Shi, Z.; Liu, X.

10.1101/2020.01.15.907840 — animal behavior and cognition — Posted on 2020-01-15

2101 Can we predict real-time fMRI neurofeedback learning success from pre-training brain activity?

Haugg, A.; Sladky, R.; Skouras, S.; McDonald, A.; Craddock, C.; Kirschner, M.; Herdener, M.; Koush, Y.; Papoutsi, M.; Keynan, J. N.; Hendler, T.; Cohen Kadosh, K.; Zich, C.; MacInnes, J.; Adcock, A.; Dickerson, K.; Chen, N.-K.; Young, K.; Bodurka, J.; Yao, S.; Becker, B.; Auer, T.; Schweizer, R.; Pamplona, G.; Emmert, K.; Haller, S.; Van De Ville, D.; Blefari, M. L.; Kim, D.-Y.; Lee, J.-H.; Marins, T. F.; Megumi, F.; Sorger, B.; Kamp, T.; Liew, S.-L.; Veit, R.; Spetter, M.; Weiskopf, N.; Scharnowski, F.

10.1101/2020.01.15.906388 — neuroscience — Posted on 2020-01-15

2102 Target of Rapamycin: function in abiotic stress tolerance in Arabidopsis and its involvement in a possible cross-talk with ribosomal proteins

Bakshi, A.; Moin, M.; Madhav, M. S.; Gayatri, M. B.; Reddy, A. B. M.; Datla, R.; Kirti, P. B.

10.1101/2020.01.15.907899 — plant biology — Posted on 2020-01-15

2103 Dynamics of sphingolipids and the serine-palmitoyltransferase complex in oligodendrocytes during myelination.

Davis, D. L.; Mahawar, U.; Pope, V. S.; Allegood, J.; Sato-Bigbee, C.; Wattenberg, B. W.

10.1101/2020.01.15.908277 — neuroscience — Posted on 2020-01-15

2104 Polycomb regulation is coupled to cell cycle transition in pluripotent stem cells

Asenjo, H. G.; Gallardo, A.; Lopez-Onieva, L.; Tejada, I.; Martorell-Marugan, J.; Carmona-Saez, P.; Landeira, D.

10.1101/2020.01.15.907519 — molecular biology — Posted on 2020-01-15

2105 Linked-read sequencing enables haplotype-resolved resequencing at population scale

Lutgen, D.; Ritter, R.; Olsen, R.-A.; Schielzeth, H.; Gruselius, J.; Ewels, P. A.; Garcia, J. T.; Shirihai, H.; Schweizer, M.; Suh, A.; Burri, R.

10.1101/2020.01.15.907261 — evolutionary biology — Posted on 2020-01-15

2106 Quantifying Epithelial Plasticity as a Platform to Reverse Epithelial Injury

Nishida, K.; Ghosh, B.; Chandrala, L.; Mahmud, S.; Chen, S.; Khosla, A. A.; Katz, J.; Sidhaye, V. K.

10.1101/2020.01.14.906008 — cell biology — Posted on 2020-01-15

2107 Complementary effects of adaptation and gain control on sound encoding in primary auditory cortex

Pennington, J. R.; David, S. V.

10.1101/2020.01.14.905000 — neuroscience — Posted on 2020-01-15

2108 Development of Microstructural and Morphological Cortical Profiles in the Neonatal Brain

Fenchel, D.; Dimitrove, R.; Seidlitz, J.; Robinson, E. C.; Batalle, D.; Hutter, J.; Christiaens, D.; Pietsch, M.; Brandon, J.; Hughes, E. J.; Allsop, J.; O'Keeffe, C.; Price, A. N.; Cordero-Grande, L.; Schuh, A.; Makropoulos, A.; Passerat-Palmbach, J.; Bozek, J.; Rueckert, D.; Hajnal, J. V.; Raznahan, A.; McAlonan, G.; Edwards, A. D.; O'Muircheartaigh, J.

10.1101/2020.01.14.906206 — neuroscience — Posted on 2020-01-15

2109 Distinct components of photoperiodic light are differentially encoded by the mammalian circadian clock

Tackenberg, M.; Hughey, J.; McMahon, D. G.

10.1101/2020.01.14.906131 — neuroscience — Posted on 2020-01-15

2110 Efficient Coding in the Economics of Human Brain Connectomics

Lynn, C. W.; Cui, Z.; Ciric, R.; Baum, G. L.; Moore, T. M.; Roalf, D. R.; Detre, J. A.; Gur, R. C.; Gur, R. E.; Satterthwaite, T. D.; Bassett, D. S.

10.1101/2020.01.14.906842 — neuroscience — Posted on 2020-01-15

2111 Rod phototransduction and light signal transmission during type 2 diabetes

Becker, S.; Vinberg, F.

10.1101/2020.01.14.905265 — neuroscience — Posted on 2020-01-15

2112 25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner

Wong, M. Y.; Lewis, M.; Doherty, J. J.; Shi, Y.; Sullivan, P.; Qian, M.; Covey, D. F.; Petsko, G. A.; Holtzman, D. M.; Paul, S. M.; Luo, W.

10.1101/2020.01.14.906966 — neuroscience — Posted on 2020-01-15

2113 Prospective rewards enhance motor skill performance and skill coding in LPFC

Adkins, T. J.; Lee, T.

10.1101/2020.01.15.907006 — neuroscience — Posted on 2020-01-15

2114 Time course and shared neurocognitive mechanisms of mental imagery and visual perception

Maier, M.; Froemer, R.; Rost, J.; Sommer, W.; Abdel Rahman, R.

10.1101/2020.01.14.905885 — neuroscience — Posted on 2020-01-15

2115 An ancient satellite repeat controls gene expression and embryonic development in Aedes aegypti through a highly conserved piRNA

Halbach, R.; Miesen, P.; Joosten, J.; Tasköprü, E.; Pennings, B.; Vogels, C. B. F.; Merkling, S. H.; Koenraadt, C. J.; Lambrechts, L.; van Rij, R. P.

10.1101/2020.01.15.907428 — molecular biology — Posted on 2020-01-15

2116 Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection

Goodwin, M. L.; Webster, H. S.; Wang, H.-Y.; Jenks, J. A.; Nelson, C. S.; Tu, J.; Mangold, J.; Valencia, S.; McLellan, J. S.; Wrapp, D.; Fu, T.-M.; Zhang, N.; Freed, D.; Wang, D.; An, Z.; Permar, S. R.

10.1101/2020.01.14.907204 — immunology — Posted on 2020-01-15

2117 scTPA: A web tool for single-cell transcriptome analysis of pathway activation signatures

Su, J.; Zhang, Y.; Yu, F.; Zhang, Y.; Zhang, J.; Guo, F.; Hu, J.; Zhang, G.; Zhou, M.

10.1101/2020.01.15.907592 — genomics — Posted on 2020-01-15

2118 Reconstructing Genotypes in Private Genomic Databases from Genetic Risk Scores

Paige, B.; Bell, J.; Bellet, A.; Gascon, A.; Ezer, D.

10.1101/2020.01.15.907808 — genomics — Posted on 2020-01-15

2119 Color Data v2: a user-friendly, open-access database with hereditary cancer and hereditary cardiovascular conditions datasets

Berger, M. J.; Williams, H. E.; Barrett, R.; Zimmer, A. D.; McKennon, W.; Hong, H.; Ginsberg, J.; Zhou, A. Y.; Neben, C. L.

10.1101/2020.01.15.907212 — genetics — Posted on 2020-01-15

2120 ATF4 mediates fetal globin upregulation in response to reduced β-globin

Boontanrart, M. Y.; Stehli, G.; Banovic, M.; Schroeder, M.; Wyman, S.; Lew, R.; Bordi, M.; Gowen, B.; DeWitt, M.; Corn, J. E.

10.1101/2020.01.15.905943 — genetics — Posted on 2020-01-15

2121 Negative linkage disequilibrium between amino acid changing variants reveals interference among deleterious mutations in the human genome

Garcia, J. A.; Lohmueller, K. E.

10.1101/2020.01.15.907097 — evolutionary biology — Posted on 2020-01-15

2122 A global map of root biomass across the world's forests

Huang, Y.; Ciais, P.; Santoro, M.; Makowski, D.; Chave, J.; Schepaschenko, D.; Abramoff, R.; Goll, D. S.; Yang, H.; Chen, Y.; Wei, W.; Piao, S.

10.1101/2020.01.14.906883 — ecology — Posted on 2020-01-15

2123 The Flemmingsome reveals an ESCRT-to-membrane coupling required for completion of cytokinesis

Addi, C.; Presle, A.; Fremont, S.; Cuvelier, F.; Rocancourt, M.; Milin, F.; Schmutz, S.; Chamot-Rooke, J.; Douche, T.; Duchateau, M.; Giai Gianetto, Q.; Menager, H.; Matondo, M.; Zimmermann, P.; Gupta-Rossi, N.; Echard, A.

10.1101/2020.01.15.907857 — cell biology — Posted on 2020-01-15

2124 Pyruvate kinase controls signal strength in the insulin secretory pathway

Lewandowski, S. L.; Cardone, R. L.; Foster, H. R.; Ho, T.; Potapenko, E.; Poudel, C.; VanDeusen, H. R.; Alves, T. C.; Zhao, X.; Capozzi, M. E.; Jahan, I.; Nunemaker, C. S.; Campbell, J. E.; Thomas, C. J.; Kibbey, R. G.; Merrins, M. J.

10.1101/2020.01.15.907790 — cell biology — Posted on 2020-01-15

2125 d-PBWT: dynamic positional Burrows-Wheeler transform

Sanaullah, A.; Zhi, D.; Zhang, S.

10.1101/2020.01.14.906487 — bioinformatics — Posted on 2020-01-15

2126 Carbon limitation leads to thermodynamic regulation of aerobic metabolism

Garayburu-Caruso, V.; Stegen, J.; Song, H.-S.; Renteria, L.; Wells, J.; Garcia, W.; Resch, C. T.; Goldman, A.; Chu, R.; Toyoda, J.; Graham, E. B.

10.1101/2020.01.15.905331 — ecology — Posted on 2020-01-15

2127 Human Telomerase Expression is under Direct Transcriptional Control of the Telomere-binding-factor TRF2

Sharma, S.; Mukherjee, A. K.; Roy, S. S.; Bagri, S.; Lier, S.; Verma, M.; Sengupta, A.; Kumar, M.; Nesse, G.; Pandey, D. P.; Chowdhury, S.

10.1101/2020.01.15.907626 — cancer biology — Posted on 2020-01-15

2128 Longitudinal cancer evolution from single cells

Ramazzotti, D.; Angaroni, F.; Maspero, D.; Ascolani, G.; Castiglioni, I.; Piazza, R.; Antoniotti, M.; Graudenzi, A.

10.1101/2020.01.14.906453 — bioinformatics — Posted on 2020-01-15

2129 Development of novel anti-malarial from structurally diverse library of molecules, targeting plant-like Calcium Dependent Protein Kinase 1, a multistage growth regulator of P. falciparum

Jain, R.; Gupta, S.; Munde, M.; Pati, S.; singh, s.

10.1101/2020.01.14.907147 — biochemistry — Posted on 2020-01-15

2130 Chemical constituents involved in e-cigarette, or vaping product use-associated lung injury (EVALI)

Muthumalage, T.; Friedman, M.; McGraw, M.; Friedman, A.; Rahman, I.

10.1101/2020.01.14.905539 — pharmacology and toxicology — Posted on 2020-01-15

2131 From thoughtless awareness to effortful cognition: alpha - theta cross-frequency dynamics in experienced meditators during meditation, rest and arithmetic

Rodriguez-Larios, J.; Faber, P.; Achermann, P.; Tei, S.; Alaerts, K.

10.1101/2020.01.14.905935 — neuroscience — Posted on 2020-01-15

2132 Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations

Wang, Y.; Guo, J.; Ni, G.; Yang, J.; Visscher, P. M.; Yengo, L.

10.1101/2020.01.14.905927 — genetics — Posted on 2020-01-15

2133 Investigating the Genetic Architecture of Non-Cognitive Skills Using GWAS-by-Subtraction

Demange, P. A.; Malanchini, M.; Mallard, T. T.; Biroli, P.; Cox, S. R.; Grotzinger, A. D.; Tucker-Drob, E. M.; Abdellaoui, A.; Arseneault, L.; Caspi, A.; Corcoran, D.; Domingue, B.; Mitchell, C.; van Bergen, E.; Boomsma, D. I.; Harris, K. M.; Ip, H. F.; Moffitt, T. E.; Poulton, R.; Prinz, J.; Sugden, K.; Wertz, J.; Williams, B.; de Zeeuw, E. L.; Belsky, D. W.; Harden, K. P.; Nivard, M. G.

10.1101/2020.01.14.905794 — genetics — Posted on 2020-01-15

2134 Quantification of amyloid fibril polymorphism by nano-morphometry reveals the individuality of filament assembly

Aubrey, L. D.; Blakeman, B. J. F.; Lutter, L.; Serpell, C.; Tuite, M.; Serpell, L.; Xue, W.-F.

10.1101/2020.01.14.905877 — biophysics — Posted on 2020-01-15

2135 Removable cranial window for sustained wide-field optical imaging in mouse neocortex

Cha, S. S.; Bucklin, M. E.; Han, X.

10.1101/2020.01.14.905851 — bioengineering — Posted on 2020-01-15

2136 Parallel evolution in the integration of a co-obligate aphid symbiosis

Monnin, D.; Jackson, R.; Kiers, E. T.; Bunker, M.; Ellers, J.; Henry, L. M.

10.1101/2020.01.14.905752 — evolutionary biology — Posted on 2020-01-15

2137 Should I shrink or should I flow? - body size adjustment to thermo-oxygenic niche

Walczynska, A.; Gudowska, A.; Sobczyk, L.

10.1101/2020.01.14.905901 — evolutionary biology — Posted on 2020-01-15

2138 Distinct neural signals in speech preparation differentially modulate auditory responses

Li, S.; Zhu, H.; Tian, X.

10.1101/2020.01.14.905620 — neuroscience — Posted on 2020-01-15

2139 Distinct signals in medial and lateral VTA dopamine neurons modulate fear extinction at different times

Cai, L.; Pizano, K.; Gundersen, G.; Hayes, C.; Fleming, W.; Witten, I. B.

10.1101/2020.01.14.906024 — neuroscience — Posted on 2020-01-15

2140 Ignoring fossil age uncertainty leads to inaccurate topology and divergence times in time calibrated tree inference

Barido-Sottani, J.; van Tiel, N.; Hopkins, M. J.; Wright, D. F.; Stadler, T.; Warnock, R. C.

10.1101/2020.01.14.906107 — evolutionary biology — Posted on 2020-01-15

2141 Mining downy mildew susceptibility genes: a diversity study in grapevine.

Pirrello, C.; Zeilmaker, T.; Bianco, L.; Giacomelli, L.; Moser, C.; Vezzulli, S.

10.1101/2020.01.15.898700 — plant biology — Posted on 2020-01-15

2142 Creation of a novel trigeminal tractography atlas for automated trigeminal nerve identification

Zhang, F.; Xie, G.; Leung, L.; Mooney, M.; Epprecht, L.; Norton, I.; Rathi, Y.; Kikinis, R.; Al-Mefty, O.; Makris, N.; Golby, A. J.; O'Donnell, L. J.

10.1101/2020.01.15.904938 — neuroscience — Posted on 2020-01-15

2143 Controlling water hyacinth infestation in Lake Tana using fungal pathogen from Laboratory level up to pilot scale

Admas, A.; Sahile, S.; Agidie, A.; Menale, H.; Gedefaw, T.; Teshome, M.

10.1101/2020.01.14.901140 — microbiology — Posted on 2020-01-15

2144 Expanding the Genetic Architecture of Nicotine Dependence and its Shared Genetics with Multiple Traits: Findings from the Nicotine Dependence GenOmics (iNDiGO) Consortium

Quach, B. C.; Bray, M. J.; Gaddis, N. C.; Liu, M.; Palviainen, T.; Minica, C. C.; Zellers, S.; Sherva, R.; Aliev, F.; Nothnagel, M.; Young, K. A.; Marks, J.; Young, H.; Guo, Y.; Waldrop, A.; Sey, N.; Landi, M. T.; McNeil, D. W.; Farrer, L. A.; Markunas, C. A.; Vink, J.; Hottenga, J.-J.; Iacono, W. G.; Kranzler, H. R.; Saccone, N. L.; Neale, M. C.; Madden, P.; Rietschel, M.; Marazita, M. L.; McGue, M.; Won, H.; Winterer, G.; Grucza, R.; Dick, D.; Gelernter, J.; Caporaso, N. E.; Baker, T. B.; Boomsma, D. I.; Kaprio, J.; Hokanson, J. E.; Vrieze, S.; Bierut, L. J.; Johnson, E. O.; Hancock, D. B.

10.1101/2020.01.15.898858 — genomics — Posted on 2020-01-15

2145 Evolutionary causes of lifespan extension by dietary restriction: linking theory and mechanisms

Travers, L. M.; Carlsson, H.; Duxbury, E. M. L.; Maklakov, A. A.

10.1101/2020.01.14.904599 — evolutionary biology — Posted on 2020-01-15

2146 Genome wide sequencing provides evidence of adaptation to heterogeneous environments for the ancient relictual Circaeaster agrestis (Circaeasteraceae, Ranunculales)

Zhang, X.; Sun, Y.; Landis, J. B.; Zhang, J.; Yang, L.; Lin, N.; Zhang, H.; Guo, R.; Li, L.; Zhang, Y.; Deng, T.; Sun, H.; Wang, H.

10.1101/2020.01.14.902643 — evolutionary biology — Posted on 2020-01-15

2147 Differences in mitochondrial activity trigger cell competition during early mouse development.

Lima, A.; Lubatti, G.; Burgstaller, J.; Hu, D.; Green, A.; di Gregorio, A.; Zawadzki, T.; Pernaute, B.; Mahammadov, E.; Dore, M.; Sanchez, J. M.; Bowling, S.; Sancho, M.; Karimi, M.; Carling, D.; Jones, N.; Srinivas, S.; Scialdone, A.; Rodriguez, T. A.

10.1101/2020.01.15.900613 — developmental biology — Posted on 2020-01-15

2148 Deep Brain Stimulation: Imaging on a group level

Treu, S.; Strange, B.; Oxenford, S.; Kuehn, A.; Li, N.; Horn, A.

10.1101/2020.01.14.904615 — neuroscience — Posted on 2020-01-15

2149 Glucocorticoid Receptor ablation promotes cardiac regeneration by hampering cardiomyocyte terminal differentiation

Pianca, N.; Pontis, F.; Chirivi, M.; Papa, V.; Braga, L.; Patnala, R. S.; Bongiovanni, C.; Mazzeschi, M.; Umansky, K. B.; Cenacchi, G.; Lauriola, M.; Giacca, M.; Rizzi, R.; Tzahor, E.; D'Uva, G.

10.1101/2020.01.15.901249 — cell biology — Posted on 2020-01-15

2150 SREBP1 regulates mitochondrial metabolism in oncogenic KRAS expressing NSCLC

Ruiz, C. F.; Haley, J. A.; Montal, E. D.; Haley, J. D.

10.1101/2020.01.15.896373 — cancer biology — Posted on 2020-01-15

2151 Dispersal limitation and fire feedbacks maintain mesic savannas in Madagascar

Goel, N.; Vleck, E. V.; Aleman, J. C.; Staver, A. C.

10.1101/2020.01.14.905208 — ecology — Posted on 2020-01-15

2152 Neuraminidase activity mediates IL-6 production through TLR4 and p38/ERK MAPK signaling in MRL/lpr mesangial cells

Sundararaj, K. P.; Rodgers, J.; Angel, P.; Wolf, B.; Nowling, T. K.

10.1101/2020.01.15.908160 — cell biology — Posted on 2020-01-15

2153 Discriminating tactile speed in absence of raised texture elements: Role of deformation and vibratory cues

Moscatelli, A.; Ryan, C. P.; Ciotti, S.; Cosentino, L.; Ernst, M. O.; Lacquaniti, F.

10.1101/599522 — neuroscience — Posted on 2020-01-15

2154 Fast and efficient generation of knock-in human organoids using homology-independent CRISPR/Cas9 precision genome editing

Artegiani, B.; Hendriks, D.; Beumer, J.; Kok, R.; Zheng, X.; Joore, I.; Chuva de Sousa Lopes, S.; van Zon, J.; Tans, S.; Clevers, H.

10.1101/2020.01.15.907766 — cell biology — Posted on 2020-01-15

2155 Near-infrared light increases functional connectivity with a non-thermal mechanism

Dmochowski, G. M.; Shereen, A. D.; Berisha, D.; Dmochowski, J.

10.1101/459883 — neuroscience — Posted on 2020-01-15

2156 Visually evoked responses are enhanced when engaging in a video game

Ki, J. J.; Parra, L. C.; Dmochowski, J.

10.1101/588806 — neuroscience — Posted on 2020-01-15

Mei, N.; Olafsson, E.; Rankine, S.; Soto, D.

10.1101/607069 — neuroscience — Posted on 2020-01-15

2158 A novel role for the tumor suppressor gene ITF2 in lung tumorigenesis and chemotherapy response

Pernia, O.; Sastre-Perona, A.; Rodriguez-Antolin, C.; Garcia-Guede, A.; Palomares-Bralo, M.; Rosas, R.; Sanchez-Cabrero, D.; Rodriguez, C.; Martin-Arenas, R.; Pulido, V.; de Castro, J.; Santisteban, P.; Vera, O.; Ibanez de Caceres, I.

10.1101/517169 — cancer biology — Posted on 2020-01-15

2159 Functional gene categories differentiate maize leafdrought-related microbial epiphytic communities

Methe, B. A.; Hiltbrand, D.; Roach, J.; Xu, W.; Gordon, S. G.; Goodner, B. W.; Stapleton, A. E.

10.1101/104331 — microbiology — Posted on 2020-01-15

2160 Automated Change Detection Methods for Satellite Data that can Improve Conservation Implementation

Evans, M. J.; Malcom, J. W.

10.1101/611459 — ecology — Posted on 2020-01-15

2161 Dissociation of connectivity for syntactic irregularity and perceptual ambiguity in musical chord stimuli

Kim, C. H.; Jin, S.-H.; Kim, J. S.; Kim, Y.; Yi, S. W.; Chung, C. K.

10.1101/2020.01.12.903583 — neuroscience — Posted on 2020-01-15

2162 Highly diverse mesophotic reef fish communities in Raja Ampat, West Papua

Andradi-Brown, D. A.; Beer, A. J. E.; Colin, L.; Hastuti, ; Head, C. E. I.; Hidayat, N. I.; Lindfield, S. J.; Mitchell, C. R.; Pada, D. N.; Piesinger, N. M.; Purwanto, ; Ahmadia, G. N.

10.1101/640490 — ecology — Posted on 2020-01-15

2163 Reduced PABPN1 levels causes cytoskeleton disorganization and aberrant differentiation

Raz, V.; van der Wal, E.; Domagoj, C.; Olie, C. S.; Maton, L.; de Greef, J. C.; Lin, I.-H.; Chen, Y.-F.; Kareem, E.; Penninger, J. M.; Kessler, B.

10.1101/2020.01.15.907311 — cell biology — Posted on 2020-01-15

2164 Age-Stage, Two-Sex Life Table of the Menochilus sexmaculatus (Coccinellidae: Coleoptera) Feeding on Different Aphid Species

Abbas, K.; Zaib, M. S.; Zakria, M.; Hani, U.-e.; Zaka, S. M.; Ain, N.-u.

10.1101/2020.01.15.907576 — zoology — Posted on 2020-01-15

2165 Leptin Resistance in the Ovary of Obese Mice Is Associated with Profound Changes in the Transcriptome of Cumulus Cells

Wolodko, K.; Walewska, E.; Adamowski, M.; Castillo-Fernandez, J.; Kelsey, G. D.; Galvao, A.

10.1101/729657 — physiology — Posted on 2020-01-15

2166 Roles of sarcoplasmic reticulum Ca2+ ATPase pump in the impairments of lymphatic contractile activity in a metabolic syndrome rat model

Lee, Y.; Chakraborty, S.; Muthuchamy, M.

10.1101/2020.01.14.906503 — physiology — Posted on 2020-01-15

2167 Modulation of white matter bundle connectivity in the presence of axonal truncation pathologies

Smith, R. E.; Calamante, F.; Gajamange, S.; Kolbe, S.; Connelly, A.

10.1101/2020.01.14.903559 — neuroscience — Posted on 2020-01-15

2168 Physiological significance of proteolytic processing of Reelin revealed by cleavage-resistant Reelin knock-in mice

Okugawa, E.; Ogino, H.; Shigenobu, T.; Yamakage, Y.; Tsuiji, H.; Oishi, H.; Kohno, T.; Hattori, M.

10.1101/2020.01.15.903237 — neuroscience — Posted on 2020-01-15

2169 Sources of Off-Target Effects of Vagus Nerve Stimulation Using the Helical Clinical Lead in Domestic Pigs

Nicolai, E. N.; Settell, M. L.; Knudsen, B. E.; McConico, A. L.; Gosink, B. A.; Trevathan, J. K.; Baumgart, I. W.; Ross, E. K.; Pelot, N. A.; Grill, W. M.; Gustafson, K. J.; Shoffstall, A. J.; Williams, J. C.; Ludwig, K. A.

10.1101/2020.01.15.907246 — neuroscience — Posted on 2020-01-15

2170 Dynamin-like proteins are essential for vesicle biogenesis in Mycobacterium tuberculosis.

Gupta, S.; Palacios, A.; Khataokar, A.; Weinrick, B.; Lavin, J. L.; Sampedro, L.; Gil, D.; Anguita, J.; Menendez, M. C.; Garcia, M. J.; Dogra, N.; Neiditch, M. B.; Prados-Rosales, R.; Rodriguez, G. M.

10.1101/2020.01.14.906362 — microbiology — Posted on 2020-01-15

2171 Deletion of RsmE 16S rRNA methyltransferase leads to low level increase in aminoglycoside resistance in Mycobacterium smegmatis

Bijpuria, S.; Sharma, R.; Taneja, B.

10.1101/2020.01.15.907279 — microbiology — Posted on 2020-01-15

2172 Differential Nr4a1 and Nr4a3 expression discriminates tonic from activated TCR signalling events in vivo

Jennings, E. K.; Elliot, T. A. E.; Thawait, N.; Kanabar, S. S.; Yam-Puc, J. C.; Ono, M.; Toellner, K.-M.; Wraith, D. C.; Anderson, G.; Bending, D.

10.1101/767566 — immunology — Posted on 2020-01-15

2173 Sampling artifacts in single-cell genomics cohort studies

Massoni-Badosa, R.; Iacono, G.; Moutinho, C.; Kulis, M.; Palau, N.; Marchese, D.; Rodriguez-Ubreva, J.; Ballestar, E.; Rodriguez-Esteban, G.; Marsal, S.; Aymerich, M.; Colomer, D.; Campo, E.; Jula, A.; Martin-Subero, J. I.; Heyn, H.

10.1101/2020.01.15.897066 — genomics — Posted on 2020-01-15

2174 Genetic associations at regulatory phenotypes improve fine-mapping of causal variants for twelve immune-mediated diseases

Kundu, K.; Mann, A. L.; Tardaguila, M.; Watt, S.; Ponstingl, H.; Vasquez, L.; Morrell, N. W.; Stegle, O.; Pastinen, T.; Sawcer, S. J.; Anderson, C. A.; Walter, K.; Soranzo, N.

10.1101/2020.01.15.907436 — genomics — Posted on 2020-01-15

2175 Complex sex-specific age-related changes in DNA methylation including variability, epimutations and entropy

Yusipov, I.; Bacalini, M. G.; Kalyakulina, A.; Krivonosov, M.; Pirazzini, C.; Gensous, N.; Ravaioli, F.; Milazzo, M.; Vedunova, M.; Fiorito, G.; Gagliardi, A.; Polidoro, S.; Garagnani, P.; Ivanchenko, M.; Franceschi, C.

10.1101/2020.01.15.905224 — genomics — Posted on 2020-01-15

2176 Initial virome characterization of the common cnidarian lab model Nematostella vectensis

Lewandowska, M.; Hazan, Y.; Moran, Y.

10.1101/2020.01.14.906370 — evolutionary biology — Posted on 2020-01-15

2177 A Genetically Encoded Fluorescent Sensor Enables Real-time Detection of the Intracellular GTP:GDP Ratio

Zhang, J.; Song, Y.; Liu, S.; Wang, W.; Zhang, M.; Yang, G.; Zou, P.; Wang, J.

10.1101/614412 — biochemistry — Posted on 2020-01-15

2178 Early metazoan origin and multiple losses of a novel clade of RIM pre-synaptic calcium channel scaffolding protein homologues

Piekut, T.; Wong, Y. Y.; Walker, S. E.; Smith, C. L.; Gauberg, J.; Harracksingh, A. N.; Lowden, C.; Cheng, H.-Y. M.; Spencer, G. E.; Senatore, A.

10.1101/2020.01.14.906610 — evolutionary biology — Posted on 2020-01-15

2179 TOP the Transcription Orientation Pipeline and its use to investigate the transcription of non-coding regions: assessment with CRISPR direct repeats and intergenic sequences.

Houenoussi, K.; Boukheloua, R.; Vernadet, J.-P.; Gautheret, D.; Vergnaud, G.; Pourcel, C.

10.1101/2020.01.15.903914 — bioinformatics — Posted on 2020-01-15

2180 Synthesis of geological and comparative phylogeographic data point to climate, not mountain uplift, as driver of divergence across the Eastern Andean Cordillera

Rodriguez-Munoz, E.; Montes, C.; Crawford, A. J.

10.1101/2020.01.14.906982 — evolutionary biology — Posted on 2020-01-15

2181 What drives male association tendencies in wild zebrafish? Role of female and vegetation densities

Ghoshal, A.; Bhat, A.

10.1101/2020.01.14.907139 — animal behavior and cognition — Posted on 2020-01-15

2182 Dendritic normalisation improves learning in sparsely connected artificial neural networks

Bird, A. D.; Cuntz, H.

10.1101/2020.01.14.906537 — neuroscience — Posted on 2020-01-15

2183 A regulatory domain in the K2P2.1 (TREK-1) carboxyl-terminal allows for channel activation by monoterpenes

Arazi, E.; Blecher, G.; Zilberberg, N.

10.1101/2020.01.14.906396 — neuroscience — Posted on 2020-01-15

2184 Oxidative stress delays development and alters gene function in the agricultural pest moth, Helicoverpa armigera

Apirajkamol, N.; James, B.; Walsh, T. K.; McGaughran, A.

10.1101/2020.01.14.906958 — evolutionary biology — Posted on 2020-01-15

2185 Quantifying the impact of Human Leukocyte Antigen on the human gut microbiome

Andeweg, S. P.; Kesmir, C.; Dutilh, B. E.

10.1101/2020.01.14.907196 — bioinformatics — Posted on 2020-01-15

2186 A Pathway and Network Oriented Approach to Enlighten Molecular Mechanisms of Type 2 Diabetes Using Multiple Association Studies

Bakir-Gungor, B.; Unlu Yazici, M.; Goy, G.; Temiz, M.

10.1101/2020.01.14.905547 — bioinformatics — Posted on 2020-01-15

2187 Maternal genome dominance in early plant embryogenesis

Alaniz-Fabian, J.; Xiang, D.; Del Toro-De Leon, G.; Orozco-Nieto, A.; Gao, P.; Sharpe, A.; Kochian, L. V.; Selvaraj, G.; Springer, N. M.; Abreu-Goodger, C.; Datla, R.; Gillmor, S.

10.1101/2020.01.14.905992 — plant biology — Posted on 2020-01-15

2188 Neuronal LXR Regulates Neuregulin-1 Expression and Sciatic Nerve-Associated Cell signaling

Gavini, C.; Bonomo, R.; Mansuy-Aubert, V.

10.1101/2020.01.14.907048 — neuroscience — Posted on 2020-01-15

2189 A bead-based method for the removal of the amino acid lysine from cell-free transcription-translation systems

Finkler, M.; Kurt, O.; Grimm, F.; Hartz, P.; Ott, A.

10.1101/2020.01.15.907360 — molecular biology — Posted on 2020-01-15

2190 An integrated platform to systematically identify causal variants and genes for polygenic human traits.

Downes, D. J.; Schwessinger, R.; Hill, S. J.; Nussbaum, L.; Scott, C.; Gosden, M. E.; Hirschfeld, P. P.; Telenius, J. M.; Eijsbouts, C. E.; McGowan, S. J.; Cutler, A. J.; Kerry, J.; Davies, J. L.; Dendrou, C. A.; Inshaw, J. R. J.; Larke, M. S. C.; Oudelaar, A. M.; Bozhilov, Y.; King, A.; Brown, R. C.; Suciu, M. C.; Davies, J. O. J.; Hublitz, P.; Fisher, C.; Kurita, R.; Nakamura, Y.; Taylor, S.; Buckle, V. J.; Todd, J. A.; Higgs, D. R.; Hughes, J. R.

10.1101/813618 — genetics — Posted on 2020-01-15

2191 Evolutionary forces on A-to-I RNA editing revealed by sequencing individual honeybee drones

Duan, Y.; Dou, S.; Huang, J.; Eisenberg, E.; Lu, J.

10.1101/2020.01.15.907287 — evolutionary biology — Posted on 2020-01-15

2192 Protein kinase Cϵ activation induces EHD-dependent degradation and downregulation of KATP channels: Implications for glucose stimulated insulin secretion

Cockcroft, C. J.; Manna, P.; Karnik, R.; Taneja, T.; Wrighton, D.; Mankouri, J. T.; Rong, H.; Sivaprasadarao, A.

10.1101/2020.01.15.907386 — cell biology — Posted on 2020-01-15

2193 PAX2 Induces Tubular-Like Structures in Normal and Ovarian Cancer Cells

Alwosaibai, K. S.; Alamri, S.; Garson, K.; Vanderhyden, B.

10.1101/2020.01.14.906438 — cancer biology — Posted on 2020-01-15

2194 Molecular packing structure of fibrin fibers resolved by X-ray scattering and molecular modeling

Jansen, K. A.; Zhmurov, A.; Vos, B. E.; Portale, G.; Merino, D. H.; Litvinov, R. I.; Tutwiler, V.; Kurniawan, N. A.; Bras, W.; Weisel, J. W.; Barsegov, V.; Koenderink, G. H.

10.1101/2020.01.15.907253 — biophysics — Posted on 2020-01-15

2195 A Bayesian nonparametric semi-supervised model for integration of multiple single-cell experiments

Verma, A.; Engelhardt, B. E.

10.1101/2020.01.14.906313 — bioinformatics — Posted on 2020-01-15

2196 Nobiletin Affects Circadian Rhythms and Oncogenic Characteristics in a Cell-Dependent Manner

Lellupitiyage Don, S. S.; Robertson, K. L.; Lin, H.-H.; Labriola, C.; Harrington, M. E.; Taylor, S. R.; Farkas, M. E.

10.1101/2020.01.14.906420 — cancer biology — Posted on 2020-01-15

2197 Harnessing intrinsic fluorescence for typing of secondary structures of DNA

Zuffo, M.; Gandolfini, A.; Heddi, B.; Granzhan, A.

10.1101/2020.01.15.907501 — biophysics — Posted on 2020-01-15

2198 Bioluminescence dynamics in single germinating bacterial spores reveal metabolic heterogeneity

Frentz, Z.; Dworkin, J.

10.1101/2020.01.14.906875 — biophysics — Posted on 2020-01-15

2199 Predicting transcription factor binding in single cells through deep learning

Fu, L.; Zhang, L.; Dollinger, E.; Peng, Q.; Nie, Q.; Xie, X.

10.1101/2020.01.14.905232 — bioinformatics — Posted on 2020-01-15

2200 Mechanical Regulation of Microvascular Angiogenesis

Ruehle, M. A.; Eastburn, E. A.; LaBelle, S. A.; Krishnan, L.; Weiss, J. A.; Boerckel, J. D.; Wood, L. B.; Guldberg, R. E.; Willett, N. J.

10.1101/2020.01.14.906354 — bioengineering — Posted on 2020-01-15

2201 The Nonequilibrium Mechanism of Noise Enhancer synergizing with Activator in HIV Latency Reactivation

Guo, X.; Tang, T.; Duan, M.; Zhang, L.; Ge, H.

10.1101/2020.01.14.905653 — systems biology — Posted on 2020-01-15

2202 Sponge Physioecology On Moorea, French Polynesia: Local Distribution And Filtration Efficiency Of Lamellodysidea Under Varying Temperatures

Leveque-Eichhorn, L.

10.1101/2020.01.14.906990 — physiology — Posted on 2020-01-15

2203 Loss of the Er81 Transcription Factor in Cholinergic Cells Alters Striatal Activity and Habit Formation

Ranjbar-Slamloo, Y.; Ahmed, N. Y.; Al Abed, A. S.; Gao, L.; Sontani, Y.; RComH Cheo Gauthier, A.; Arabzadeh, E.; Dehorter, N.

10.1101/2020.01.14.905497 — neuroscience — Posted on 2020-01-15

2204 Biodiversity Of Bacteriophages From Lysed Batch Culture Of Recombinant Escherichia Coli BL21(DE3) Examined By Anion Exchange Chromatography And TEM

Kushkina, A. I.; Tovkach, F. I.

10.1101/2020.01.15.907352 — microbiology — Posted on 2020-01-15

2205 Non-invasive monitoring of drug action: a new live in vitro assay design for Chagas' disease drug discovery

Fesser, A. F.; Braissant, O.; Olmo, F.; Kelly, J. M.; Kaiser, M.; Maeser, P.

10.1101/2020.01.15.907220 — microbiology — Posted on 2020-01-15

2206 Phosphatidylinositol Acyl Chains Configure TLR-Dependent Priming and Activation of the NLRP3 Inflammasome

Hamilton, C.; Larrouy-Maumus, G.; Anand, P. K.

10.1101/2020.01.14.905075 — immunology — Posted on 2020-01-15

2207 Development of humanized mouse and rat models with full-thickness human skin and autologous immune cells

Agarwal, Y.; Beatty, C.; Ho, S.; Thurlow, L.; Das, A.; Kelly, S.; Castronova, I.; Salunke, R.; Biradar, S.; Yeshi, T.; Richardson, A.; Bility, M. T.

10.1101/2020.01.14.906255 — immunology — Posted on 2020-01-15

2208 SMRT sequencing of the Oryza rufipogon genome reveals the genomic basis of rice adaptation

Li, W.; Li, K.; Huang, Y.; Shi, C.; Hu, W.-S.; Zhang, Y.; Zhang, Q.-J.; Xia, E.-H.; Hutang, G.-R.; Zhu, X.-G.; Liu, Y.-L.; Liu, Y.; Tong, Y.; Zhu, T.; Huang, H.; Zhang, D.; Zhao, Y.; Jiang, W.-K.; Yuan, J.; Niu, Y.-C.; Gao, C.-W.; Gao, L.-Z.

10.1101/2020.01.14.905281 — genomics — Posted on 2020-01-15

2209 Characterisation of the genetic architecture of immune-mediated disease through informed dimension reduction

Burren, O. S.; Reales, G.; Wong, L.; Bowes, J.; Lee, J. C.; Barton, A.; Lyons, P. A.; Smith, K. G.; Thomson, W.; Kirk, P. D.; Wallace, C.

10.1101/2020.01.14.905869 — genetics — Posted on 2020-01-15

2210 High evolutionary potential in the chemical defenses of an aposematic Heliconius butterfly

Mattila, A. L. K.; Jiggins, C. D.; Opedal, O. H.; Montejo-Kovacevich, G.; de Castro, E.; McMillan, W. O.; Bacquet, C.; Saastamoinen, M.

10.1101/2020.01.14.905950 — evolutionary biology — Posted on 2020-01-15

2211 Hedgehog signaling is required for endomesodermal patterning and germ cell development in Nematostella vectensis

Gibson, M. C.; Chen, C.-Y.; McKinney, S. A.; Ellington, L. R.

10.1101/2020.01.15.907238 — developmental biology — Posted on 2020-01-15

2212 Loss of mitochondrial localization of human FANCG causes defective FANCJ helicase

Mukhopadhyay, S. S.; K, J. C. B.; Kapoor, B. S.; Mandal, K.; Ghosh, S.; Mokhamatam, R. B.; Manna, S. K.

10.1101/2020.01.15.907303 — cancer biology — Posted on 2020-01-15

2213 Quantitative Analysis of Tissue Secretome Reveals the Diagnostic and Prognostic Value of Carbonic Anhydrase II in Hepatocellular Carcinoma

Xing, X.; Yuan, H.; Liu, H.; Tan, X.; Zhao, B.; Wang, Y.; Ouayng, J.; Lin, M.; Huang, A.; Liu, X.-L.

10.1101/2020.01.15.905687 — cancer biology — Posted on 2020-01-15

2214 Transport Phenomena in Fluid Films with Curvature Elasticity

Mahapatra, A.; Saintillan, D.; Rangamani, P.

10.1101/2020.01.14.906917 — biophysics — Posted on 2020-01-15

2215 The synergistic actions of hydrolytic genes in coexpression networks reveal the potential of Trichoderma harzianum for cellulose degradation

Almeida, D. A.; Horta, M. A. C.; Ferreira Filho, J. A.; Murad, N. F.; de Souza, A. P.

10.1101/2020.01.14.906529 — bioinformatics — Posted on 2020-01-15

2216 Analysis of gene expression and connectivity on hippocampus of Alzheimer's disease by a new comprehensive approach

Jiang, S.

10.1101/2020.01.14.906446 — systems biology — Posted on 2020-01-15

2217 Plant-derived Cellulose Scaffolds for Bone Tissue Engineering.

Leblanc Latour, M.; Tarar, M.; Hickey, R. J.; Cuerrier, C. M.; Catelas, I.; Pelling, A. E.

10.1101/2020.01.15.906677 — bioengineering — Posted on 2020-01-15

2218 Molecular Pathways Resultant in Fever due to Inhibitory Effects of Binding PGE2 to Glucocorticoid Receptors

Schaper, C.

10.1101/2020.01.14.907105 — systems biology — Posted on 2020-01-15

2219 Identification of phosphosites that alter protein thermal stability

Smith, I. R.; Hess, K. N.; Bakhtina, A.; Valente, A. S.; Rodriguez-Mias, R. A.; Villen, J.

10.1101/2020.01.14.904300 — systems biology — Posted on 2020-01-15

2220 Molecular signatures of local adaptation to light in Norway Spruce: role of lignin mediated immunity

Ranade, S.; Garcia-Gil, M. R.

10.1101/2020.01.14.905810 — plant biology — Posted on 2020-01-15

2221 CHLOROPLAST UNUSUAL POSITIONING 1 is a new type of actin nucleation factor in plants

Kong, S.-G.; Shimada, A.; Kijima, S. T.; Hirose, K.; Katoh, K.; Ahn, J.; Higa, T.; Takano, A.; Nakamura, Y.; Suetsugu, N.; Kohda, D.; Uyeda, T. Q. P.; Wada, M.

10.1101/2020.01.14.905984 — plant biology — Posted on 2020-01-15

2222 Clustered γ-Protocadherins Regulate Cortical Interneuron Programmed Cell Death.

Mancia Leon, W. R.; Spatazza, J.; Rakela, B.; Chatterjee, A.; Pande, V.; Maniatis, T.; Hasenstaub, A. R.; Stryker, M. P.; Alvarez-Buylla, A.

10.1101/2020.01.14.906941 — neuroscience — Posted on 2020-01-15

2223 SETD7-mediated lysine monomethylation is abundant on non-hyperphosphorylated nuclear Tau

Bichmann, M.; Prat Oriol, N.; Ercan-Herbst, E.; Schoendorf, D. C.; Gomez Ramos, B.; Schwaerzler, V.; Haberkant, P.; Gasparini, L.; Ehrnhoefer, D. E.

10.1101/2020.01.14.905786 — neuroscience — Posted on 2020-01-15

2224 Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity

Wu, X.; Shukla, R.; Alganem, K.; DePasquale, E. A.; Reigle, J.; Simmons, M.; Hahn, C.-G.; Haroutunian, V.; Meller, J.; Meador-Woodruff, J.; McCullumsmith, R.

10.1101/2020.01.14.906214 — neuroscience — Posted on 2020-01-15

2225 LRP::FLAG reduces phosphorylated tau levels in Alzheimer's Disease

Cuttler, K.; Bignoux, M.; Otgaar, T. C.; Chigumba, S.; Ferreira, E.; Weiss, S. F.

10.1101/2020.01.14.905661 — neuroscience — Posted on 2020-01-15

2226 A Temporal Quantitative Profiling of Newly Synthesized Proteins during Aβ Accumulation

ma, Y.; McClatchy, D.; Martinez-Bartolome, S.; Bamberger, C.; Yates, J. R.

10.1101/2020.01.14.906560 — neuroscience — Posted on 2020-01-15

2227 Rerouting of an Esx substrate pair from the ESX-1 type VII secretion system to ESX-5 by modifying a PE/PPE substrate pair

Damen, M. P. M.; Phan, T. H.; Ummels, R.; Rubio-Canalejas, A.; Bitter, W.; Houben, E. N. G.

10.1101/2020.01.15.906685 — molecular biology — Posted on 2020-01-15

2228 RNA-Binding and Prion Domains: The Yin and Yang of Phase Separation

Lorenzo-Gotor, N.; Armaos, A.; Calloni, G.; Vabulas, M.; Sanchez de Groot, N.; Tartaglia, G. G.

10.1101/2020.01.14.904383 — molecular biology — Posted on 2020-01-15

2229 Architecture and self-assembly of the Clostridium sporogenes/botulinum spore surface illustrate a general protective strategy across spore formers

Janganan, T. K.; Mullin, N.; Dafis-Sagarmendi, A.; Brunt, J.; Tzokov, S.; Stringer, S.; Moir, A.; Chaudhuri, R.; Fagan, R. P.; Hobbs, J. K.; Bullough, P. A.

10.1101/2020.01.14.906404 — microbiology — Posted on 2020-01-15

2230 A mitochondria-targeted antioxidant and a thyroid hormone affect carotenoid ketolase gene expression and bill redness in zebra finches

Cantarero, A.; Andrade, P.; CARNEIRO, M.; MORENO-BORRALLO, A.; Alonso-Alvarez, C.

10.1101/2020.01.14.905745 — evolutionary biology — Posted on 2020-01-15

2231 Repeated evolution of circadian clock dysregulation in cavefish populations

Mack, K. L.; Jaggard, J. B.; Persons, J. L.; Passow, C. N.; Stanhope, B. A.; Ferrufino, E.; Tsuchiya, D.; Smith, S. E.; Slaughter, B. D.; Kowalko, J. E.; Rohner, N.; Keene, A. C.; McGaugh, S. E.

10.1101/2020.01.14.906628 — evolutionary biology — Posted on 2020-01-15

2232 The conservation status and population decline of the African penguin deconstructed in space and time

Sherley, R. B.; Crawford, R. J. M.; de Blocq, A. D.; Dyer, B. M.; Geldenhuys, D.; Hagen, C.; Kemper, J.; Makhado, A. B.; Pichegru, L.; Upfold, L.; Visagie, J.; Waller, L. J.; Winker, H.

10.1101/2020.01.15.907485 — ecology — Posted on 2020-01-15

2233 Sox2 modulation increases naive pluripotency plasticity

Tremble, K.; Stirparo, G. G.; Bates, L. E.; Maskalenka, K.; Stuart, H. T.; Jones, K.; Andersson-Rolf, A.; Radzisheuskaya, A.; Koo, B.-K.; Bertone, P.; Silva, J. C. R.

10.1101/2020.01.14.906933 — developmental biology — Posted on 2020-01-15

2234 Atf-6 regulates lifespan through ER-mitochondrial calcium homeostasis

Burkewitz, K.; Dutta, S.; Kelley, C. A.; Steinbaugh, M.; Cram, E. J.; Mair, W. B.

10.1101/2020.01.14.906693 — cell biology — Posted on 2020-01-15

2235 Iron and lipocalin-2 modulate cellular responses in the tumor micro-environment of pancreatic ductal adenocarcinoma

Pita-Grisanti, V.; Dangel, A. W.; Gumpper, K.; Ludwig, A.; Ueltschi, O.; Mo, X. M.; Pietrzak, M.; Webb, A.; Hwang, R. F.; Traczek, M.; Badi, N.; Cruz-Monserrate, Z.

10.1101/2020.01.14.907188 — cancer biology — Posted on 2020-01-15

2236 Temperature controlled high-throughput magnetic tweezers show striking difference in activation energies of replicating viral RNA-dependent RNA polymerases.

Seifert, M.; van Nies, P.; Papini, F. S.; Arnold, J. J.; Poranen, M. M.; Cameron, C. E.; Depken, M.; Dulin, D.

10.1101/2020.01.15.906032 — biophysics — Posted on 2020-01-15

2237 In-Silico Investigation of Luminol, Its Analogues and Improved Mechanism of Chemiluminescence for Blood Identification Beyond Forensics

Fatoki, T. H.

10.1101/2020.01.08.899617 — bioinformatics — Posted on 2020-01-15

2238 Gapless assembly of maize chromosomes using long read technologies

Dawe, K.; Liu, J.; Seetharam, A. S.; Chougule, K.; Ou, S.; Swentowsky, K. W.; Gent, J. I.; Llaca, V.; Woodhouse, M.; Manchanda, N.; Presting, G. G.; Kudrna, D.; Alabady, M.; Hirsch, C.; Fengler, K.; Ware, D.; Michael, T.; Hufford, M.

10.1101/2020.01.14.906230 — bioinformatics — Posted on 2020-01-15

2239 Pseudoreplication bias in single-cell studies; a practical solution

Zimmerman, K. D.; Espeland, M. A.; Langefeld, C. D.

10.1101/2020.01.15.906248 — bioinformatics — Posted on 2020-01-15

2240 A calibrated optogenetic toolbox of stable zebrafish opsin lines

Antinucci, P.; Dumitrescu, A.; Deleuze, C.; Morley, H. J.; Leung, K.; Hagley, T.; Kubo, F.; Baier, H.; Bianco, I. H.; Wyart, C.

10.1101/2020.01.13.904185 — neuroscience — Posted on 2020-01-15

2241 The origin of domestication genes in goats

Zheng, Z.; Wang, X.; Li, M.; Li, Y.; Yang, Z.; Wang, X.; Pan, X.; Gong, M.; Zhang, Y.; Guo, Y.; Wang, Y.; Liu, J.; Cai, Y.; Chen, Q.; Okpeku, M.; Colli, L.; Cai, D.; Wang, K.; Huang, S.; S. Sonstegard, T.; Esmailizadeh, A.; Zhang, W.; Zhang, T.; Xu, Y.; Xu, N.; Yang, Y.; Han, J.; Chen, L.; Lesur, J.; G. Daly, K.; G. Bradley, D.; Heller, R.; Zhang, G.; Wang, W.; Chen, Y.; Jiang, Y.

10.1101/2020.01.14.905505 — genomics — Posted on 2020-01-15

2242 Canonical Wnt-signaling modulates the tempo of dendritic growth of adult-born hippocampal neurons

Heppt, J.; Wittman, M.-T.; Zhang, J.; Vogt-Weisenhorn, D.; Prakash, N.; Wurst, W.; Taketo, M. M. M.; Lie, D. C.

10.1101/2020.01.14.905919 — neuroscience — Posted on 2020-01-15

2243 Abiotic and biotic drivers underly short- and long-term soil respiration responses to experimental warming in a dryland ecosystem

Dacal, M.; Garcia-Palacios, P.; Asensio, S.; Gozalo, B.; Ochoa, V.; Maestre, F.

10.1101/2020.01.13.903880 — ecology — Posted on 2020-01-15

2244 Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures

de March, C. A.; Titlow, W. B.; Sengoku, T.; Breheny, P.; Matsunami, H.; McClintock, T. S.

10.1101/865386 — cell biology — Posted on 2020-01-15

2245 The activity-dependent transcription factor Npas4 regulates IQSEC3 expression in somatostatin interneurons to mediate anxiety-like behavior

Kim, S.; Park, D.; Kim, J.; Lee, D.; Kim, D.; Kim, H.; Hong, S.; Jeon, J.; Kim, J.; Cheong, E.; Um, J. W.; Ko, J.

10.1101/659805 — neuroscience — Posted on 2020-01-15

2246 Parallel Factor Analysis for multidimensional decomposition of fNIRS data - A validation study

Husser, A. M.; Caron-Desrochers, L.; Tremblay, J.; Vannasing, P.; Martinez-Montes, E.; Gallagher, A.

10.1101/806778 — neuroscience — Posted on 2020-01-15

2247 Single-cell repertoire tracing identifies rituximab refractory B cells during myasthenia gravis relapses

Jiang, R.; Fichtner, M. L.; Hoehn, K. B.; Stathopoulos, P.; Nowak, R. J.; Kleinstein, S.; OConnor, K. C.

10.1101/840389 — immunology — Posted on 2020-01-15

2248 Identifying novel B-cell targets for chronic inflammatory autoimmune disease by screening of chemical probes in a patient-derived cell assay

Sundstrom, Y.; Shang, M.-M.; Panda, S. K.; Gronwall, C.; Wermeling, F.; Gunnarsson, I.; Lundberg, I. E.; Sundstrom, M.; Jakobsson, P.-J.; Berg, L.

10.1101/2020.01.08.898270 — immunology — Posted on 2020-01-15

2249 Discovery of genes required for body axis and limb formation by global identification of retinoic acid regulated epigenetic marks

Berenguer, M.; Meyer, K. F.; Yin, J.; Duester, G.

10.1101/778191 — developmental biology — Posted on 2020-01-15

2250 Potpourri: An Epistasis Test Prioritization Algorithm via Diverse SNP Selection

Caylak, G.; Tastan, O.; Cicek, A. E.

10.1101/830216 — bioinformatics — Posted on 2020-01-15

2251 Divergent receptor proteins confer responses to different karrikins in two ephemeral weeds

Sun, Y. K.; Yao, J.; Scaffidi, A.; Melville, K.; Davies, S. F.; Bond, C. S.; Smith, S. M.; Flematti, G. R.; Waters, M. T.

10.1101/376939 — plant biology — Posted on 2020-01-15

2252 The RAB32/BLOC-3 dependent pathway mediates host-defence against different pathogens in human macrophages

Baldassarre, M.; Solano-Collado, V.; Balci, A.; Colamarino, R.; Dambuza, I. M.; Reid, D. M.; Wilson, H. M.; Brown, G. D.; Mukhopadhyay, S.; Dougan, G.; Spano, S.

10.1101/570531 — microbiology — Posted on 2020-01-15

2253 The stem rust fungus Puccinia graminis f. sp. tritici induces waves of small RNAs with opposing profiles during wheat infection

Sperschneider, J.; Jacques, S.; Xu, B.; Upadhyaya, N.; Mago, R.; Jones, A. W.; Schwessinger, B.; Figueroa, M.; Singh, K.; Stone, E.; Wang, M.-B.; Taylor, J.; Dodds, P.

10.1101/469338 — microbiology — Posted on 2020-01-15

2254 Quantifying colour difference in animals with variable patterning

Drackova, T.; Smolinsky, R.; Hiadlovska, Z.; Dolinay, M.; Martinkova, N.

10.1101/859074 — ecology — Posted on 2020-01-15

2255 Testing for Dependence on Tree Structures

Behr, M.; Ansari, M. A.; Munk, A.; Holmes, C.

10.1101/622811 — bioinformatics — Posted on 2020-01-15

2256 Variant Phasing and Haplotypic Expression from Single-molecule Long-read Sequencing in Maize

Wang, B.; Tseng, E.; Baybayan, P.; Eng, K.; Regulski, M.; Jiao, Y.; Wang, L.; Olson, A.; Chougule, K.; Van Buren, P.; Ware, D.

10.1101/654533 — bioinformatics — Posted on 2020-01-15

2257 Generation of scale-invariant sequential activity in linear recurrent networks

Liu, Y.; Howard, M. W.

10.1101/580522 — neuroscience — Posted on 2020-01-15

2258 Negative regulation of the Rcs phosphorelay via IgaA contact with the RcsD phosphotransfer protein

Wall, E. A.; Majdalani, N.; Gottesman, S.

10.1101/2020.01.14.906271 — microbiology — Posted on 2020-01-14

2259 Interaction of 14-3-3I and CDPK1 mediates the growth of human malaria parasite

Jain, R.; Dey, P.; Gupta, S.; Pati, S.; Bhattacherjee, A.; Munde, M.; Singh, S.

10.1101/2020.01.14.906479 — cell biology — Posted on 2020-01-14

2260 Condensin I subunit Cap-G is essential for proper gene expression during the maturation of post-mitotic neurons

Hassan, A.; Araguas Rodriguez, P.; Heidmann, S. H. K.; Walmsley, E. L.; Aughey, G. N.; Southall, T. D.

10.1101/2020.01.14.904409 — developmental biology — Posted on 2020-01-14

2261 Evaluation of modulators of cAMP-response in terms of their impact on cell cycle and mitochondrial activity of Leishmania donovani

Saha, A.; Bhattacharjee, A.; Vij, A.; Das, P. K.; Bhattacharya, A.; BISWAS, A.

10.1101/2020.01.14.906321 — cell biology — Posted on 2020-01-14

2262 Myofiber stretch induces tensile and shear deformation of muscle stem cells in their native niche

Haroon, M.; Klein-Nulend, J.; Bakker, A. D.; Jin, J.; Offringa, C.; Le Grand, F.; Giordani, L.; Liu, K. J.; Knight, R. D.; Jaspers, R. T.

10.1101/2020.01.14.902510 — cell biology — Posted on 2020-01-14

2263 Highly coordinated mechanical motion mediated by the microtubule cytoskeletonis a pivotal element of de-novo symmetry breaking in hydraspheroids

Sander, H.; Pasula, A.; Sander, M.; Giri, V.; Terriac, E.; Lautenschlaeger, F.; Ott, A.

10.1101/2020.01.14.906115 — biophysics — Posted on 2020-01-14

2264 Correlative Fluorescence and Electron Microscopy of Whole Breast Cancer Cells Reveals Differential Distribution of ErbB2 Dependent on Underlying Actin

Dahmke, I. N.; Trampert, P.; Mostajeran, Z.; Lautenschlaeger, F.; de Jonge, N.

10.1101/2020.01.14.906040 — biophysics — Posted on 2020-01-14

2265 Machine learning and dengue forecasting: Comparing random forests and artificial neural networks for predicting dengue burdens at the national sub-national scale in Colombia

Zhao, N.; Charland, K.; Carabali, M.; Nsoesie, E.; Maher-Giroux, M.; Rees, E.; Yuan, M.; Garcia Balaguera, C.; Jaramillo Ramirez, G.; Zinszer, K.

10.1101/2020.01.14.906297 — immunology — Posted on 2020-01-14

2266 A non-canonical RNAi pathway controls virulence and genome stability in Mucorales

Nicolas, F. E.; Garre, V.; Navarro, E.; Murcia, L.; Perez-Arques, C.; Navarro-Mendoza, M. I.

10.1101/2020.01.14.906289 — genetics — Posted on 2020-01-14

2267 Simultaneous Determination of Contents of Flavonol Glycosides and Terpene Lactones in Ginkgo Biloba Tablets by Ultra High Performance Liquid Chromatography Tandem Single Quadrupole Mass Spectrometry Detector

Ma, L.; Zhang, J.; Jin, W.-r.; Wang, S.

10.1101/2020.01.14.906347 — biochemistry — Posted on 2020-01-14

2268 Moderating Effect of Social Support on Role Conflict and Job Satisfaction Among Nurses with Multiple Roles

Li, C.; Song, R.; Fan, X.; XU, L.

10.1101/2020.01.14.906263 — scientific communication and education — Posted on 2020-01-14

2269 Tidal volume and respiration phase modulate cortico-muscular communication

Kluger, D. S.; Gross, J.

10.1101/2020.01.13.904524 — neuroscience — Posted on 2020-01-14

2270 PD-L1 upregulation by IFN-α/γ-mediated Stat1 suppresses anti-HBV T cell response

Meng, S.; Liu, L.; Hou, J.; Qin, L.; Liu, W.; Zhang, H.; Li, Y.; Chen, M.; Deng, M.; Zhao, B.; Hu, J.; Zheng, H.

10.1101/2020.01.14.906339 — molecular biology — Posted on 2020-01-14

2271 Green tea infusion aggravates nutritional status of the juvenile untreated STZ-induced type 1 diabetic rat

Ladeira, L. C. M.; dos Santos, E. C.; Mendes, B. F.; Gutierrez, E. A.; Santos, C. F. F.; de Souza, F. B.; Machado-Neves, M.; Maldonado, I. R. d. S. C.

10.1101/2020.01.13.904896 — pathology — Posted on 2020-01-14

2272 Regulated repression, and not activation, governs the cell fate promoter controlling yeast meiosis

Tam, J.; van Werven, F.

10.1101/2020.01.13.904912 — molecular biology — Posted on 2020-01-14

2273 Learning to Encode Cellular Responses to Systematic Perturbations with Deep Generative Models

Xue, Y.; Ding, M. Q.; Lu, X.

10.1101/2020.01.14.906768 — bioinformatics — Posted on 2020-01-14

2274 Combined Treatment with Dopamine Receptor Antagonists and Radiation Creates a Metabolic Vulnerability in Mouse Models of Glioblastoma

Saki, M.; Bhat, K.; Cheng, F.; He, L.; Ioannidis, A.; Nathanson, D.; Tsang, J.; Nghiemphu, P. L.; Cloughesy, T. F.; Liau, L. M.; Kornblum, H.; Pajonk, F.

10.1101/2020.01.13.905380 — neuroscience — Posted on 2020-01-14

2275 Neural oscillatory activities in separate frequencies encode hierarchically distinct visual features

Date, H.; Kawasaki, K.; Hasegawa, I.; Okatani, T.

10.1101/2020.01.13.902775 — neuroscience — Posted on 2020-01-14

2276 Rotten-skin disease significantly changed giant spiny frog(Paa spinosa) gut microbiota

he, t.; Jiang, y.; wang, p.; xiang, j.; pan, w.

10.1101/2020.01.13.905588 — microbiology — Posted on 2020-01-14

2277 Colorectal cancer marker identification using the aging immune system-related blood cell DNA methylome

Quan, Y.; Liang, F.; Wu, D.; Zhu, Y.; Chen, Y.; Wu, A.; Tang, D.; Huang, B.; Xu, R.; Ning, Z.; Li, Y.; Xiong, J.

10.1101/2020.01.13.905299 — cancer biology — Posted on 2020-01-14

2278 Intraspinal stimulation with silicon-based 3D microelectrode array for bladder voiding in cats before and after spinal cord injury

Pikov, V.; Han, M.; McCreery, D. B.

10.1101/2020.01.13.905364 — bioengineering — Posted on 2020-01-14

2279 Differential functional connectivity underlying asymmetric reward-related activity in human and non-human primates

Lopez-Persem, A.; Roumazeilles, L.; Folloni, D.; Marche, K.; Fouragnan, E. F.; Khalighinejad, N.; Rushworth, M. F.; Sallet, J.

10.1101/2020.01.13.904565 — neuroscience — Posted on 2020-01-14

2280 Characterizing dysbiosis of gut microbiome in PD: Evidence for overabundance of opportunistic pathogens

Wallen, Z. D.; Appah, M.; Dean, M. N.; Sesler, C. L.; Factor, S. A.; Molho, E.; Zabetian, C. P.; Standaert, D. G.; Payami, H.

10.1101/2020.01.13.905166 — genomics — Posted on 2020-01-14

2281 Species-specific, age-varying plant traits affect herbivore growth and survival

Yang, L. H.; Cenzer, M. L.; Morgan, L. J.; Hall, G. W.

10.1101/2020.01.14.906859 — ecology — Posted on 2020-01-14

2282 Hypercluster: a flexible tool for parallelized unsupervised clustering optimization

Blumenberg, L. M.; Ruggles, K. V.

10.1101/2020.01.13.905323 — bioinformatics — Posted on 2020-01-14

2283 The connector between the kinase and RNase domains of IRE1α transmits the conformational change that underlies ER stress-induced activation.

Ricci, D.; Tutton, S.; Marrocco, I.; Ying, M.; Blumenthal, D.; Eletto, D.; Vargas, J.; Boyle, S.; Fazelinia, H.; Paton, J. C.; Paton, A. W.; Tang, C.-H. A.; Hu, C.-C. A.; Gidalevitz, T.; Argon, Y.

10.1101/2020.01.14.902395 — biochemistry — Posted on 2020-01-14

2284 Structural Analysis of the PATZ1 BTB domain homodimer

Piepoli, S.; Alt, A. O.; Atilgan, C.; Mancini, E. J.; Erman, B.

10.1101/2020.01.13.903898 — molecular biology — Posted on 2020-01-14

2285 SIMPLEs: a single-cell RNA sequencing imputation strategy preserving gene modules and cell clusters variation

Hu, Z.; Zu, S.; Liu, J. S.

10.1101/2020.01.13.904649 — bioinformatics — Posted on 2020-01-14

2286 Structure of the teneurin-latrophilin complex: Alternative splicing controls synapse specificity by a novel mechanism

Li, J.; Xie, Y.; Cornelius, S.; Jiang, X.; Kordon, S. P.; Sando, R.; Pan, M.; Leon, K.; Sudhof, T. C.; Zhao, M.; Arac, D.

10.1101/2020.01.13.901090 — biochemistry — Posted on 2020-01-14

2287 Impact of phosphorylation on thermal stability of proteins

Potel, C. M.; Kurzawa, N.; Becher, I.; Typas, A.; Mateus, A.; Savitski, M. M.

10.1101/2020.01.14.903849 — systems biology — Posted on 2020-01-14

2288 Defoliation-induced compensatory transpiration is compromised in SUT4-RNAi Populus

Harding, S. A.; Frost, C. J.; Tsai, C.-J.

10.1101/2020.01.13.905406 — plant biology — Posted on 2020-01-14

2289 Hierarchical organization of the human subcortex unveiled with functional connectivity gradients

Tian, Y.; Margulies, D. S.; Breakspear, M.; Zalesky, A.

10.1101/2020.01.13.903542 — neuroscience — Posted on 2020-01-14

2290 Microbial Source Tracking in the Love Creek Watershed, Delaware (USA)

Main, C. R.; Tyler, R.; Lopez, K.; Heurta, S.

10.1101/2020.01.13.900647 — microbiology — Posted on 2020-01-14

2291 Educational attainment polygenic scores in Hungary: evidence for validity and a historical gene-environment interaction

Ujma, P. P.; Eszlari, N.; Millinghoffer, A.; Bruncsics, B.; Petschner, P.; Antal, P.; Deakin, B.; Bagdy, G.; Juhasz, G.

10.1101/2020.01.13.905034 — genetics — Posted on 2020-01-14

2292 ATR Inhibitors as Potent Modulators of DNA End Resection Capacity

Dibitetto, D.; Sims, J. R.; Ascencao, C. F. R.; Feng, K.; Freire, R.; Smolka, M. B.

10.1101/2020.01.13.905059 — cancer biology — Posted on 2020-01-14

2293 Quantitative single cell heterogeneity profiling of patient derived tumor initiating gliomaspheres reveals unique signatures of malignancy and response

Masterman-Smith, M.; Graham, N. A.; Panosyan, E.; Mottahedeh, J.; Samuels, E. E.; Nunez, A.; Lim, S. H.; Phillips, T.; Choe, M.; Visnyei, K.; Yong, W. H.; Graeber, T. G.; Lang, M.-F.; Kornblum, H.; Sun, J.

10.1101/2020.01.14.900506 — cancer biology — Posted on 2020-01-14

2294 Generalized calibration across LC-setups for generic prediction of small molecule retention times

Bouwmeester, R.; Martens, L.; Degroeve, S.

10.1101/2020.01.14.905844 — bioinformatics — Posted on 2020-01-14

2295 metan: an R package for multi-environment trial analysis

Olivoto, T.; Dal'Col Lucio, A.

10.1101/2020.01.14.906750 — bioinformatics — Posted on 2020-01-14

2296 Protein Corona Composition and Dynamics on Carbon Nanotubes in Blood Plasma and Cerebrospinal Fluid

Pinals, R. L.; Yang, D.; Rosenberg, D. J.; Chaudhary, T.; Crothers, A. R.; Iavarone, A. T.; Hammel, M.; Landry, M. P.

10.1101/2020.01.13.905356 — bioengineering — Posted on 2020-01-14

2297 Solid-Phase Peptide Capture and Release for Bulk and Single-Molecule Proteomics

Howard, C. J.; Floyd, B. M.; Bardo, A. M.; Swaminathan, J.; Marcotte, E. M.; Anslyn, E. V.

10.1101/2020.01.13.904540 — biochemistry — Posted on 2020-01-14

2298 A multi-phase flux balance model reveals flexibility of guard cell central carbon metabolism

Tan, X. L. J.; Cheung, C. Y. M.

10.1101/2020.01.13.905372 — plant biology — Posted on 2020-01-14

2299 Distraction attenuates goal-directed neural responses for food rewards

Duif, I.; Wegman, J.; de Graaf, K.; Smeets, P. A. M.; Aarts, E.

10.1101/2020.01.13.904532 — neuroscience — Posted on 2020-01-14

2300 Sensory and Behavioral Components of Neocortical Signal Flow in Discrimination Tasks with Short-term Memory

Gallero-Salas, Y.; Laurenczy, B.; Voigt, F. F.; Gilad, A.; Helmchen, F.

10.1101/2020.01.13.904284 — neuroscience — Posted on 2020-01-14

2301 Streptococcus pneumoniae infection promotes histone H3 dephosphorylation by modulating host PP1 phosphatase

Dong, W.; Rasid, O.; Chevalier, C.; Connor, M.; Eldridge, M.; Hamon, M. A.

10.1101/2020.01.14.905968 — microbiology — Posted on 2020-01-14

2302 Dynamic metabolic reprogramming in dendritic cells: an early response to influenza infection that is essential for effector function

Smallwood, H.; Rezinciuc, S.; Bezavada, L.; Bahadoran, A.; Dan, S.; Wang, R.; Ferrer, D. L.; Zink, E. E.; Finklestein, D.; Green, D. R.; Tolic, L. P.; Thomas, P. G.

10.1101/2020.01.14.906826 — immunology — Posted on 2020-01-14

2303 Patch size distribution and network connectivity affect species invasion dynamics in dendritic networks

Holenstein, K.; Harvey, E.; Altermatt, F.

10.1101/2020.01.13.903070 — ecology — Posted on 2020-01-14

2304 WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility

Kabrawala, S.; Zimmer, M.; Campellone, K.

10.1101/2020.01.14.906784 — cell biology — Posted on 2020-01-14

2305 ntJoin: Fast and lightweight assembly-guided scaffolding using minimizer graphs

Coombe, L.; Nikolic, V.; Chu, J.; Birol, I.; Warren, R. L.

10.1101/2020.01.13.905240 — bioinformatics — Posted on 2020-01-14

2306 Algorithmic Learning for Auto-deconvolution of GC-MS Data to Enable Molecular Networking within GNPS.

Aksenov, A.; Laponogov, I.; Zhang, Z.; Doran, S.; Belluomo, I.; Veselkov, D.; Bittremieux, W.; Nothias, L. F.; Nothias-Esposito, M.; Maloney, K. N.; Misra, B. B.; Melnik, A. V.; Jones, K. L.; Dorrestein, K.; Panitchpakdi, M.; Ernst, M.; van der Hooft, J. J. J.; Gonzalez, M.; Carazzone, C.; Amézquita, A.; Callewaert, C.; Morton, J.; Quinn, R. A.; Bouslimani, A.; Albarracin Orio, A.; Petras, D.; Smania, A. M.; Couvillion, S. P.; Burnet, M. C.; Nicora, C. D.; Zink, E.; Metz, T. O.; Artaev, V.; Humston-Fulmer, E.; Gregor, R.; Meijler, M. M.; Mizrahi, I.; Eyal, S.; Anderson, B.; Dutton, R. J.

10.1101/2020.01.13.905091 — bioinformatics — Posted on 2020-01-14

2307 BNrich: A Bayesian network approach to the pathway enrichment analysis

Maleknia, S.; Sharifi-Zarchi, A.; Rezaei Tabar, V.; Namazi, M.; Kavousi, K.

10.1101/2020.01.13.905448 — bioinformatics — Posted on 2020-01-14

2308 Genetic ablation of the mitochondrial ribosome in Plasmodium falciparum sensitizes the human malaria parasite to antimalarial drugs targeting mitochondrial functions

Ling, L.; Mulaka, M.; Munro, J.; Dass, S.; Mather, M. W.; Riscoe, M. K.; Llinas, M.; Zhou, J.; Ke, H.

10.1101/2020.01.14.906198 — biochemistry — Posted on 2020-01-14

2309 Deep Evolutionary History of the Phox and Bem1 (PB1) Domain Across Eukaryotes

Mutte, S.; Weijers, D.

10.1101/2020.01.13.903906 — evolutionary biology — Posted on 2020-01-14

2310 Integrative analysis identifies candidate tumor microenvironment and intracellular signaling pathways that define tumor heterogeneity in NF1

Banerjee, J.; Allaway, R. J.; Taroni, J. N.; Baker, A.; Zhang, X.; Moon, C. I.; Blakeley, J. O.; Guinney, J.; Hirbe, A.; Greene, C. S.; Gosline, S. J.

10.1101/2020.01.13.904771 — systems biology — Posted on 2020-01-14

2311 Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens

Goncalves, E.; Segura-Cabrera, A.; Pacini, C.; Picco, G.; Behan, F.; Jaaks, P.; Coker, E. A.; van der Meer, D.; Barthorpe, A.; Lightfoot, H.; Leach, A. R.; Lynch, J. T.; Sidders, B.; Crafter, C.; Iorio, F.; Fawell, S.; Garnett, M. J.

10.1101/2020.01.14.905729 — systems biology — Posted on 2020-01-14

2312 Mg2+ modulates the activity of hyperpolarization-activated calcium currents in plant cells

Lemtiri-Chlieh, F.; Arold, S.; Gehring, C.

10.1101/2020.01.14.906123 — plant biology — Posted on 2020-01-14

2313 Microbiome composition differs in hybrid and inbred maize

Wagner, M. R.; Roberts, J. H.; Balint-Kurti, P. J.; Holland, J. B.

10.1101/2020.01.13.904979 — plant biology — Posted on 2020-01-14

2314 Cardiac Microlesions Form During Severe Bacteremic Enterococcus faecalis Infection

Brown, A. O.; Singh, K. V.; Cruz, M. R.; Kaval, K. G.; Francisco, L. E.; Murray, B. E.; Garsin, D. A.

10.1101/2020.01.14.906669 — microbiology — Posted on 2020-01-14

2315 Salmonella Enteritidis Effector AvrA suppresses autophagy by reducing Beclin-1 protein

Jiao, Y.; Zhang, Y.-g.; LIN, Z.; Lu, R.; Xia, Y.; Meng, C.; Pan, Z.; Xu, X.; Jiao, X.-a.; Sun, J.

10.1101/2020.01.13.905596 — microbiology — Posted on 2020-01-14

2316 Taking extreme measures: A quantitative study of multiple stress interactions at the limits of life.

Cane, R.; Cockell, C.

10.1101/2020.01.13.905562 — microbiology — Posted on 2020-01-14

2317 Optical microscopy reveals the dynamic nature of B. pseudomallei morphology during β-lactam antimicrobial susceptibility testing

McLaughlin, H. P.; Bugrysheva, J.; Sue, D.

10.1101/2020.01.13.904995 — microbiology — Posted on 2020-01-14

2318 Recessive deleterious variation has a limited impact on signals of adaptive introgression in human populations

Zhang, X.; Kim, B. Y.; Lohmueller, K. E.; Huerta-Sanchez, E.

10.1101/2020.01.13.905174 — evolutionary biology — Posted on 2020-01-14

2319 A novel redox-active switch in Fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily

Shrestha, S.; Katiyar, S.; Sanz-Rodriguez, C. E.; Kemppinen, N. R.; Kim, H. W.; Kadirvelraj, R.; Panagos, C.; Keyhaninejad, N.; Colonna, M.; Chopra, P.; Byrne, D. P.; Boons, G. J.; Knaap, E. V.; Eyers, P.; Edison, A. S.; Wood, Z. A.; Kannan, N.

10.1101/2020.01.13.904870 — biochemistry — Posted on 2020-01-14

2320 Molecular Choreography of Acute Exercise

Contrepois, K.; Wu, S.; Moneghetti, K. J.; Hornburg, D.; Ahadi, S.; Tsai, M.-S.; Metwally, A. A.; Wei, E.; Lee-McMullen, B.; Quijada, J. V.; Chen, S.; Christle, J. W.; Ellenberger, M.; Balliu, B.; Taylor, S.; Durrant, M.; Knowles, D. A.; Choudhry, H.; Ashland, M.; Bahmani, A.; Enslen, B.; Amsallem, M.; Kobayashi, Y.; Avina, M.; Perelman, D.; Schussler-Fiorenza Rose, S. M.; Zhou, W.; Ashley, E. A.; Montgomery, S. B.; Chaib, H.; Haddad, F.; Snyder, M. P.

10.1101/2020.01.13.905349 — systems biology — Posted on 2020-01-14

2321 Chronic downregulation of parvalbumin-positive cell activity accelerates early perceptual learning but impairs end performance

Cisneros-Franco, M.; Thomas, M. E.; Regragui, I.; Lane, C. P.; Ouellet, L.; de Villers-Sidani, E.

10.1101/2020.01.13.905257 — neuroscience — Posted on 2020-01-14

2322 SpikeForest: reproducible web-facing ground-truth validation of automated neural spike sorters

Magland, J. F.; Jun, J. J.; Lovero, E.; Morley, A. J.; Hurwitz, C. L.; Buccino, A. P.; Garcia, S.; Barnett, A. H.

10.1101/2020.01.14.900688 — neuroscience — Posted on 2020-01-14

2323 Fluidity of gender identity induced by illusory body-sex change.

Tacikowski, P.; Fust, J.; Ehrsson, H. H.

10.1101/2020.01.13.905315 — neuroscience — Posted on 2020-01-14

2324 Adaptive repulsion of long-term memory representations is triggered by event similarity

Chanales, A. J. H.; Tremblay-McGaw, A. G.; Kuhl, B. A.

10.1101/2020.01.14.900381 — neuroscience — Posted on 2020-01-14

2325 Varying co-factor requirements for MAML1-dependent transcription at different Notch-responsive target genes

Rogers, J. M.; Guo, B.; Egan, E.; Aster, J. C.; Adelman, K.; Blacklow, S.

10.1101/2020.01.13.905612 — molecular biology — Posted on 2020-01-14

2326 Factor VIII exhibits chaperone-dependent and glucose-regulated reversible amyloid formation in the endoplasmic reticulum

Poothong, J.; Pottekat, A.; Siirin, M.; Campos, A. R.; Paton, A. W.; Paton, J. C.; Acosta, J. - L.; Chen, Z.; Swift, M.; Volkmann, N.; Hanein, D.; Yong, J.; Kaufman, R. J.

10.1101/2020.01.13.905190 — molecular biology — Posted on 2020-01-14

2327 Antisense targeting of decoy exons can reduce intron retention and increase protein expression in human erythroblasts

Parra, M.; Zhang, W.; Vu, J.; DeWitt, M. A.; Conboy, J. G.

10.1101/2020.01.13.902544 — molecular biology — Posted on 2020-01-14

2328 Natural infection with Giardia is associated with altered community structure of the human and canine gut microbiome.

Berry, A. S. F.; Johnson, K.; Martins, R.; Sullivan, M.; Farias Amorim, C.; Putre, A.; Scott, A.; Wang, S.; Lindsay, B.; Baldassano, B.; Nolan, T. J.; Beiting, D. P.

10.1101/2020.01.13.905604 — microbiology — Posted on 2020-01-14

2329 Transcriptional regulation of the Nε-fructoselysine metabolism in Escherichia coli by global and substrate-specific cues

Graf von Armansperg, B.; Koller, F.; Gericke, N.; Hellwig, M.; Jagtap, P. K. A.; Heermann, R.; Hennig, J.; Henle, T.; Lassak, J.

10.1101/2020.01.13.904318 — microbiology — Posted on 2020-01-14

2330 A healthy childhood environment helps to combat inherited susceptibility to obesity

Huels, A.; Wright, M. N.; Bogl, L. H.; Kaprio, J.; Lissner, L.; Molnar, D.; Moreno, L.; De Henauw, S.; Siani, A.; Veidebaum, T.; Ahrens, W.; Pigeot, I.; Foraita, R.; IDEFICS/I.Family consortia,

10.1101/2020.01.13.905125 — genetics — Posted on 2020-01-14

2331 Mate selection provides similar genetic progress and average inbreeding than optimum contribution selection in the long-term

Yoshida, G.; Yanez, J.; Queiroz, S.; Carvalheiro, R.

10.1101/2020.01.13.904219 — genetics — Posted on 2020-01-14

2332 Intraspecific competition can generate species coexistence in a model for dryland vegetation patterns

Eigentler, L.

10.1101/2020.01.13.903179 — ecology — Posted on 2020-01-14

2333 Backstepping Based Automatically Controlled Angiogenic Inhibition Therapy

DORUK, O. R.

10.1101/2020.01.13.905067 — bioengineering — Posted on 2020-01-14

2334 Effect of Cysteine, Yeast Extract, pH Regulation and Gas Flow on Acetate and Ethanol Formation and Growth Profiles of Clostridium ljungdahlii Syngas Fermentation

Infantes, A.; Kugel, M.; Neumann, A.

10.1101/2020.01.13.904292 — bioengineering — Posted on 2020-01-14

2335 Functionalized Mesoporous Silicas Direct Structural Polymorphism of Amyloid-β Fibrils

Lucas, M. J.; Pan, H. S.; Verbeke, E. J.; Webb, L. J.; Taylor, D. W.; Keitz, B. K.

10.1101/2020.01.13.904854 — biochemistry — Posted on 2020-01-14

2336 Selecting for Chlamydomonas reinhardtii fitness in a liquid algal growth system compatible with the International Space Station Veggie plant growth chamber

Zhang, J.; Muller, B. S. F.; Tyre, K. N.; Bai, F.; Hu, Y.; Resende, M. F.; Rathinasabapathi, B.; Settles, A. M.

10.1101/2020.01.13.904342 — plant biology — Posted on 2020-01-14

2337 Spatial and functional links between cellular virological state and progression of liver fibrosis in chronic hepatitis B

Zhang, X.; Liu, D.; Lu, W.; Zheng, Y.; Wu, M.; Ding, J.; Xu, M.; Feng, Y.; Zhang, Z.; Yuan, Z.

10.1101/2020.01.13.904201 — microbiology — Posted on 2020-01-14

2338 Rapid, qualitative prediction of antimicrobial resistance by alchemical free energy methods

Fowler, P. W.

10.1101/2020.01.13.904664 — microbiology — Posted on 2020-01-14

2339 Multi valent DNA vaccine against group A human rotavirus: an in-silico investigation

Dutta, K.

10.1101/2020.01.13.903781 — immunology — Posted on 2020-01-14

2340 The completeness and stratification in yeast genotype-phenotype space

He, X.; Wang, J.

10.1101/2020.01.13.904607 — genetics — Posted on 2020-01-14

2341 Toward an understanding of the relation between gene regulation and 3D genome organization

Tian, H.; Yang, Y.; Liu, S.; Quan, H.; Gao, Y. Q.

10.1101/2020.01.13.903872 — genetics — Posted on 2020-01-14

2342 Trait-environment relationships are predictive, but not general across species

Frances, D. N.; Barber, A. J.; Tucker, C. M.

10.1101/2020.01.13.904698 — ecology — Posted on 2020-01-14

2343 sampbias, a method for quantifying geographic sampling biases in species distribution data

Zizka, A.; Antonelli, A.; Silvestro, D.

10.1101/2020.01.13.903757 — ecology — Posted on 2020-01-14

2344 Crystal structure of NirF: Insights into its role in heme d1 biosynthesis

Kluenemann, T.; Nimtz, M.; Jaensch, L.; Layer, G.; Blankenfeldt, W.

10.1101/2020.01.13.904656 — biochemistry — Posted on 2020-01-14

2345 Collective decision making by rational agents with differing preferences

Mann, R. P.

10.1101/2020.01.13.904490 — animal behavior and cognition — Posted on 2020-01-14

2346 Cross-sectional volumes and trajectories of the human brain, gray matter, white matter and cerebrospinal fluid in 9,473 typically aging adults

Irimia, A.

10.1101/2020.01.12.903658 — neuroscience — Posted on 2020-01-14

2347 Different ecological processes drive the assembly of dominant and rare root-associated bacteria in a promiscuous legume

Ramoneda, J.; Le Roux, J.; Frossard, E.; Frey, B.; Gamper, H. A.

10.1101/2020.01.13.900290 — ecology — Posted on 2020-01-14

2348 Canopy parkour: movement ecology of post-hatch dispersal in a gliding nymphal stick insect (Extatosoma tiaratum)

Zeng, Y.; Chang, S. W.; Williams, J.; Nguyen, L. Y.-N.; Tang, J. J.; Naing, M. G.; Dudley, R.

10.1101/2020.01.12.903724 — animal behavior and cognition — Posted on 2020-01-14

2349 Increased fronto-temporal connectivity by modified melody in real music

Kim, C. H.; Seol, J.; Jin, S.-H.; Kim, J. S.; Kim, Y.; Yi, S. W.; Chung, C. K.

10.1101/2020.01.12.903609 — neuroscience — Posted on 2020-01-14

2350 Pre-movement changes in sensorimotor beta oscillations predict motor adaptation drive.

Darch, H.; Cerminara, N. L.; Gilchrist, I. D.; Apps, R.

10.1101/2020.01.13.903807 — neuroscience — Posted on 2020-01-14

2351 Dicer- and BSC-dependent miRNAs during murine anagen development

Lisse, T. S.; Vishlaghi, N.

10.1101/2020.01.12.903567 — molecular biology — Posted on 2020-01-14

2352 Identification of miRNAs and their corresponding mRNA targets from chickpea root infected with M. ciceri and functional characterization of candidate miRNAs by overexpression in chickpea roots

Tiwari, M.; Singh, B.; Yadav, M.; Pandey, V.; Bhatia, S.

10.1101/2020.01.12.903260 — plant biology — Posted on 2020-01-14

2353 Windows out of Africa: A 300,000-year chronology of climatically plausible human contact with Eurasia

Beyer, R.; Krapp, M.; Eriksson, A.; Manica, A.

10.1101/2020.01.12.901694 — evolutionary biology — Posted on 2020-01-14

2354 The Camouflage Machine: Optimising protective colouration using deep learning with genetic algorithms

Fennell, J.; Talas, L.; Baddeley, R.; Cuthill, I.; Scott-Samuel, N.

10.1101/2020.01.12.903484 — animal behavior and cognition — Posted on 2020-01-14

2355 Domain segregated 3D chromatin structure and segmented DNA methylation in carcinogenesis

Xue, Y.; Yang, Y.; Tian, H.; Quan, H.; Liu, S.; Zhang, L.; Gao, Y. Q.

10.1101/2020.01.13.903963 — cancer biology — Posted on 2020-01-14

2356 Spatially organized genomic and physiological heterogeneity of the olfactory bulb mitral cell layer

Paseltiner, D.; Loeffler, H.; Andonian, A.; Leberman, A.; Gould, T. J.; Castro, J. B.

10.1101/2020.01.13.903823 — neuroscience — Posted on 2020-01-14

2357 Differential processing and localization of human Nocturnin controls metabolism of mRNA and nicotinamide dinucleotide metabolites

Abshire, E. T.; Hughes, K. L.; Diao, R.; Pearce, S.; Trievel, R. C.; Rorbach, J.; Freddolino, P. L.; Goldstrohm, A. C.

10.1101/2020.01.12.903534 — molecular biology — Posted on 2020-01-14

2358 Plastid genomics of Nicotiana (Solanaceae): insights into molecular evolution, positive selection and the origin of the maternal genome of Aztec tobacco (Nicotiana rustica)

Mehmood, F.; Abdullah, A.; Ubaid, Z.; Shahzadi, I.; Ahmed, I.; Waheed, M. T.; Poczai, P.; Mirza, B.

10.1101/2020.01.13.905158 — genomics — Posted on 2020-01-14

2359 Recent fluctuations in Mexican American genomes have altered the genetic architecture of biomedical traits

Spear, M. L.; Diaz-Papkovich, A.; Ziv, E.; Gravel, S.; Torgerson, D. G.; Hernandez, R.

10.1101/2020.01.13.905141 — genetics — Posted on 2020-01-14

2360 Cell-type specific effects of genetic variation on chromatin accessibility during human neuronal differentiation

Liang, D.; Elwell, A. L.; Aygün, N.; Lafferty, M. J.; Krupa, O.; Cheek, K. E.; Courtney, K. P.; Yusupova, M.; Garrett, M. E.; Ashley-Koch, A.; Crawford, G. E.; Love, M. I.; de la Torre-Ubieta, L.; Geschwind, D.; Stein, J. L.

10.1101/2020.01.13.904862 — genetics — Posted on 2020-01-14

2361 Adaptive parallel tempering for BEAST 2

Mueller, N. F.; Bouckaert, R.

10.1101/603514 — evolutionary biology — Posted on 2020-01-14

2362 Dissociation of connectivity for syntactic irregularity and perceptual ambiguity in musical chord stimuli

Kim, C. H.; Jin, S.-H.; Kim, J. S.; Kim, Y.; Yi, S. W.; Chung, C. K.

10.1101/2020.01.12.903583 — neuroscience — Posted on 2020-01-14

2363 A genome-wide association study highlights a regulatory role for IFNG-AS1 contributing to cutaneous leishmaniasis in Brazil

Castellucci, L. C.; Almeida, L.; Cherlin, S.; Fakiola, M.; Carvalho, E.; Figueiredo, A. B.; Cavalcanti, C. M.; Alves, N. S.; Dutra, W. O.; Gollob, K. J.; Cordell, H. J.; Blackwell, J. M.

10.1101/2020.01.13.903989 — genetics — Posted on 2020-01-14

2364 The schizophrenia risk locus in SLC39A8 alters brain metal transport and plasma glycosylation

Mealer, R. G.; Jenkins, B. J.; Chen, C.-Y.; Daly, M. J.; Ge, T.; Lehoux, S. D.; Marquardt, T.; Palmer, C. D.; Park, J. H.; Parsons, P. J.; Sackstein, R.; Williams, S. E.; Cummings, R. D.; Scolnick, E. M.; Smoller, J. W.

10.1101/757088 — biochemistry — Posted on 2020-01-14

2365 Early EEG and behavioral alterations in Dravet mice

Fadila, S.; Quinn, S.; Turchetti Maia, A.; Yakubovich, D.; Anderson, K. L.; Rubinstein, M.

10.1101/2020.01.13.904557 — neuroscience — Posted on 2020-01-14

2366 Unsupervised changes in core object recognition behavioral performance are accurately predicted by unsupervised neural plasticity in inferior temporal cortex

Jia, X.; Hong, H.; DiCarlo, J. J.

10.1101/2020.01.13.900837 — neuroscience — Posted on 2020-01-14

2367 Nigro-Thalamic Projection Controls Timing of Action Initiation

Catanese, J.; Jaeger, D.

10.1101/2020.01.12.903500 — neuroscience — Posted on 2020-01-14

2368 TRIM14 is a key regulator of the type I interferon response during Mycobacterium tuberculosis infection

Hoffpauir, C. T.; Bell, S. L.; West, K. O.; Jing, T.; Torres-Odio, S.; Cox, J. S.; West, A. P.; Li, P.; Patrick, K. L.; Watson, R. O.

10.1101/828533 — immunology — Posted on 2020-01-14

2369 A binary arginine methylation switch on histone H3 Arginine 2 regulates its interaction with WDR5

Lorton, B. M.; Harijan, R. K.; Burgos, E. S.; Bonnano, J. B.; Almo, S. C.; Shechter, D.

10.1101/2020.01.13.904581 — biochemistry — Posted on 2020-01-14

2370 Uncovering colitis pre-symptomatic state as reflected by extracellular matrix compositional and structural signatures

Shimshoni, E.; Adir, I.; Afik, R.; Solomonov, I.; Shenoy, A.; Adler, M.; Puricelli, L.; Ghini, V.; Mouhadeb, O.; Gluck, N.; Fishman, S.; Werner, L.; Shouval, D. S.; Varol, C.; Podesta, A.; Turano, P.; Geiger, T.; Milani, P.; Luchinat, C.; Alon, U.; Sagi, I.

10.1101/665653 — immunology — Posted on 2020-01-14

2371 Evolutionary dynamics of Tomato spotted wilt virus within and between alternate plant hosts and thrips

Ruark-Seward, C. L.; Bonville, B.; Kennedy, G.; Rasmussen, D. A.

10.1101/2020.01.13.904250 — evolutionary biology — Posted on 2020-01-14

2372 A multi-layered systems approach for renal cell carcinoma

Cooley, L.; Rudewicz, J.; Souleyreau, W.; Clarke, K.; Falciani, F.; Dufies, M.; Verbeke, S.; Emanuelli, A.; Benzekry, S.; Taing, C.; Ribot, E. J.; Miraux, S.; Lambrechts, D.; Modave, E.; Pineau, R.; Derieppe, M.-A.; Ambrosetti, D.; Bernhard, J.-C.; Ravaud, A.; Negrier, S.; Ferrero, J.-M.; Pages, G.; Nikolski, M.; Bikfalvi, A.

10.1101/2020.01.13.904235 — cancer biology — Posted on 2020-01-14

2373 Computational Modelling of Cell Movements and Aggregations during Kidney Organogenesis

Tikka, P.; Mercker, M.; Skovorodkin, I.; Saarela, U.; Vainio, S. J.; Marciniak-Czochra, A.; Schaefer, F.; Sluka, J. P.; Glazier, J. A.; Ronkainen, V.-P.

10.1101/2020.01.14.905711 — systems biology — Posted on 2020-01-14

2374 Within and cross species predictions of plant specialized metabolism genes using transfer learning

Moore, B. M.; Wang, P.; Fan, P.; Lee, A.; Leong, B.; Lou, Y.-L.; Schenck, C. A.; Sugimoto, K.; Last, R.; Lehti-Shiu, M. D.; Barry, C.; Shiu, S.-H.

10.1101/2020.01.13.112102 — plant biology — Posted on 2020-01-14

2375 A behavioral polymorphism caused by a single gene inside a supergene

Merritt, J. R.; Grogan, K. E.; Zinzow-Kramer, W.; Sun, D.; Ortlund, E. A.; Maney, D.; Yi, S.

10.1101/2020.01.13.897637 — neuroscience — Posted on 2020-01-14

2376 Diagnostic Cerebrospinal Fluid Biomarker Discovery and Validation in Patients with Central Nervous System Infections

10.1101/2020.01.13.899625 — microbiology — Posted on 2020-01-14

2377 Development of a soft cell confiner to decipher the impact of mechanical stimuli on cells

Prunet, A.; Lefort, S.; Delanoe-Ayari, H.; Saci, S.; Simon, G.; Argoul, F.; Guyot, B.; Rieu, J.-P.; Gobert, S.; Maguer-Satta, V.; Riviere, C.

10.1101/2020.01.04.892695 — biophysics — Posted on 2020-01-14

2378 Ribo-ODDR: Ribo-seq focused Oligo Design pipeline for experiment-specific Depletion of Ribosomal RNAs

Alkan, F.; Silva, J.; Pinto Barbera, E.; Faller, W. J.

10.1101/2020.01.12.900175 — bioinformatics — Posted on 2020-01-14

2379 Division of labor between YAP and TAZ in non-small cell lung cancer

Shreberk-Shaked, M.; Dassa, B.; Sinha, S.; Di Agostino, S.; Azuri, I.; Aylon, Y.; Blandino, G.; Ruppin, E.; Oren, M.

10.1101/2020.01.12.894733 — cancer biology — Posted on 2020-01-14

2380 Single-cell ChIP-seq imputation with SIMPA by leveraging bulk ENCODE data

Albrecht, S.; Andreani, T.; Andrade-Navarro, M. A.; Fontaine, J.-F.

10.1101/2019.12.20.883983 — bioinformatics — Posted on 2020-01-14

2381 Minimally disruptive optical control of protein tyrosine phosphatase 1B

Hongdusit, A.; Zwart, P. H.; Sankaran, B.; Fox, J. M.

10.1101/776203 — biochemistry — Posted on 2020-01-14

2382 Evolution at two-time frames shape structural variants and population structure of European plaice (Pleuronectes platessa)

Le Moan, A.; Bekkevold, D.; Hemmer-Hansen, J.

10.1101/662577 — evolutionary biology — Posted on 2020-01-14

2383 Detecting and visualising the impact of heterogeneous evolutionary processes on phylogenetic estimates

Jermiin, L. S.; Lovell, D. R.; Misof, B.; Foster, P. G.; Robinson, J.

10.1101/828996 — evolutionary biology — Posted on 2020-01-14

2384 Associations of waking cortisol with DHEA and testosterone across the pubertal transition: Effects of threat-related early life stress

King, L. S.; Graber, M. G.; Colich, N. L.; Gotlib, I. H.

10.1101/691279 — developmental biology — Posted on 2020-01-14

2385 Angiosperm speciation speeds up near the poles

Igea, J.; Tanentzap, A. J.

10.1101/619064 — evolutionary biology — Posted on 2020-01-14

2386 Reduced representation characterization of genetic and epigenetic differentiation to oil pollution in the foundation plant Spartina alterniflora

Alvarez, M.; Robertson, M.; van Gurp, T.; Wagemaker, N.; Giraud, D.; Ainouche, M.; Salmon, A.; Verhoeven, K.; Richards, C.

10.1101/426569 — ecology — Posted on 2020-01-14

2387 Correlative cryo-structured illumination fluorescence microscopy and soft X-ray tomography elucidates reovirus intracellular release pathway

Harkiolaki, M.; Kounatidis, I.; Stanifer, M. L.; Phillips, M. A.; Paul-Gilloteau, P.; Helligenstein, X.; Wang, H.; Okolo, C. A.; Fish, T.; Spink, M. C.; Stuart, D. I.; Davis, I.; Boulant, S.; Grimes, J. M.; Dobbie, I. M.

10.1101/2020.01.13.904623 — cell biology — Posted on 2020-01-14

2388 Embodied Spatial Knowledge Acquisition in Immersive Virtual Reality: Comparison of Direct Experience and Map Exploration

König, S. U.; Keshava, A.; Clay, V.; Ritterhofer, K.; Kuske, N.; König, P.

10.1101/2020.01.12.903096 — neuroscience — Posted on 2020-01-14

2389 Cortical source imaging of resting-state MEG with a high resolution atlas: An evaluation of methods

Tait, L.; Ozkan, A.; Szul, M. J.; Zhang, J.

10.1101/2020.01.12.903302 — neuroscience — Posted on 2020-01-14

2390 USP9X deubiquitinase couples the pluripotency network and cell metabolism to regulate ESC differentiation potential

de Dieuleveult, M.; Leduc, M.; Salataj, E.; Ransy, C.; Dairou, J.; Homma, K.; Le Gall, M.; Bossard, P.; Lombes, A.; Bouillaud, F.; Ferry, L.; Defossez, P.-A.; Cadoret, J.-C.; Ichijo, H.; Wood, S. A.; Guillonneau, F.; Dressel, R.; Miotto, B.

10.1101/2020.01.13.904904 — cell biology — Posted on 2020-01-14

2391 Obesity-linked PPARγ S273 phosphorylation promotes insulin resistance through Growth Differentiation Factor 3

Hall, J. A.; Ramachandran, D.; Roh, H. C.; DiSpirito, J. R.; Belchior de Oliveira, T.; Zushin, P.-J. H.; Palmer, C. J.; Hong, S.; Mina, A. I.; Liu, B.; Deng, Z.; Aryal, P.; Jacobs, C.; Tenen, D.; Brown, C. W.; Charles, J. F.; Shulman, G. I.; Kahn, B. B.; Tsai, L. T. Y.; Rosen, E.; Spiegelman, B.; Banks, A.

10.1101/2020.01.13.904953 — cell biology — Posted on 2020-01-14

2392 Migration of Cytotoxic T Lymphocytes in 3D Collagen Matrices

Sadjadi, Z.; Zhao, R.; Hoth, M.; Qu, B.; Rieger, H.

10.1101/2020.01.14.906016 — biophysics — Posted on 2020-01-14

2393 ORAI1 channels form supra-molecular clusters at rest and agglomerate into distinct plasma membrane areas of oval and strand-like shapes after activation

Peckys, D. B.; Alansary, D.; Niemeyer, B. A.; de Jonge, N.

10.1101/2020.01.13.903856 — biophysics — Posted on 2020-01-14

2394 Conservation motifs - a novel evolutionary-based classification of proteins

Beer, H.; Sherill-Rofe, D.; Unterman, I.; Bloch, I.; Isseroff, M.; Stupp, D.; Sharon, E.; Zisman, E.; Tabach, Y.

10.1101/2020.01.12.903138 — evolutionary biology — Posted on 2020-01-14

2395 CRISPR-Cas13d induces efficient mRNA knock-down in animal embryos

Kushawah, G.; Abugattas-Nunez del Prado, J.; Martinez-Morales, J. R.; DeVore, M.; Guelfo, J. R.; Brannan, E. O.; Wang, W.; Corbin, T. J.; Moran, A. M.; Sanchez Alvarado, A.; Malaga-Trillo, E.; Takacs, C. M.; Bazzini, A. A.; Moreno-Mateos, M. A.

10.1101/2020.01.13.904763 — developmental biology — Posted on 2020-01-14

2396 Chemotaxis overrides Barotaxis during Directional Decision-Making in Dictyostelium discoideum

Weijer, C. J.; Belotti, Y.; McGloin, D.

10.1101/2020.01.14.904748 — cell biology — Posted on 2020-01-14

2397 A phylogenetic analysis of MCTP proteins: from amino acid sequence to function

Tellez-Arreola, J. L.; Estrada-Mondragon, A.; Martinez-Torres, A.

10.1101/2020.01.13.904789 — cell biology — Posted on 2020-01-14

2398 Structural Analysis of a Filamentous Chaperonin from Sulfolobus solfataricus

Zeng, Y. C.; Sobti, M.; Stewart, A. G.

10.1101/2020.01.13.905216 — biophysics — Posted on 2020-01-14

2399 Dynamic interactions between the RNA chaperone Hfq, small regulatory RNAs and mRNAs in live bacterial cells

Park, S.; Prevost, K.; Heideman, E. M.; Carrier, M.-C.; Reyer, M. A.; Liu, W.; Masse, E.; Fei, J.

10.1101/2020.01.13.903641 — biophysics — Posted on 2020-01-14

2400 Single molecule mass photometry of nucleic acids

Li, Y.; Struwe, W. B.; Kukura, P.

10.1101/2020.01.14.904755 — biophysics — Posted on 2020-01-14

2401 Assessing the Extent of Structural and Dynamic Modulation of Membrane Lipids due to Pore Forming Toxins: Insights from Molecular Dynamics Simulations

Varadarajan, V.; Desikan, R.; Ayappa, K. G.

10.1101/2020.01.13.905463 — biophysics — Posted on 2020-01-14

2402 More motivated but equally good: no effect of gamification on visual working memory performance

Mystakidou, M.; van den Berg, R.

10.1101/2020.01.12.903203 — animal behavior and cognition — Posted on 2020-01-14

2403 Accelerating Prediction of Chemical Shift of Protein Structures on GPUs

Wright, E.; Ferrato, M.; Bryer, A.; Searles, R.; Perilla, J. R.; Chandrasekaran, S.

10.1101/2020.01.12.903468 — biophysics — Posted on 2020-01-14

2404 The evolution of human SIRT1 for multi-specificity is enabled by active-site adaptation

Hendler, A.; Akiva, E.; Sandhu, M.; Goldberg, D.; Arbely, E.; Jackson, C. J.; Aharoni, A.

10.1101/2020.01.12.903153 — biochemistry — Posted on 2020-01-14

2405 Voluntary actions modulate perception and neural representation of action-consequences in a hand-dependent manner

Buaron, B.; Reznik, D.; Gilron, R.; Mukamel, R.

10.1101/2020.01.12.903054 — neuroscience — Posted on 2020-01-14

2406 Increased resolution of African Swine Fever Virus genome patterns based on profile HMM protein domains

Masembe, C.; Phan, M. V. T.; Robertson, D. L.; Cotten, M.

10.1101/2020.01.12.903104 — genomics — Posted on 2020-01-14

2407 Beta-3 Adrenoreceptors protect from hypertrophic remodelling through AMP-Activated Protein Kinase and Autophagy.

Dubois-Deruy, E.; Gelinas, R.; Beauloye, C.; Esfahani, H.; Dessy, C.; Bertrand, L.; Balligand, J.-L.

10.1101/2020.01.14.905893 — cell biology — Posted on 2020-01-14

2408 mTORC2 mediate FLCN-induced HIF2α nuclear import and proliferation of clear cell renal cell carcinoma

Zhao, X.; Ma, Y.; Cui, J.; Zhao, H.; Liu, L.; Wang, Y.; Min, P.; Zhang, L.; Chen, Y.; Du, J.; Zhang, Y.; Gu, L.

10.1101/2020.01.13.905521 — cell biology — Posted on 2020-01-14

2409 Evaluating crystallographic likelihood functions using numerical quadratures

Zwart, P. H.; Perryman, D. E.

10.1101/2020.01.12.903690 — biophysics — Posted on 2020-01-14

2410 Efficient Calculation of the Genomic Relationship Matrix

Schlather, M.

10.1101/2020.01.12.903146 — bioinformatics — Posted on 2020-01-14

2411 CRISPR-mediated activation of biosynthetic gene clusters for bioactive molecule discovery in filamentous fungi

Roux, I.; Woodcraft, C.; Hu, J.; Wolters, R.; Gilchrist, C. L. M.; Chooi, Y.-H.

10.1101/2020.01.12.903286 — synthetic biology — Posted on 2020-01-14

2412 Engram reactivation during memory retrieval predicts long-term memory performance in aged mice

Gulmez Karaca, K.; Brito, D. V.; Zeuch, B.; Oliveira, A. M. M.

10.1101/2020.01.12.903088 — neuroscience — Posted on 2020-01-14

2413 Reward-driven enhancements in motor control are robust to TMS manipulation

Codol, O.; Galea, J. M.; Jalali, R.; Holland, P. J.

10.1101/2020.01.12.903419 — neuroscience — Posted on 2020-01-14

2414 Apolipoprotein E4 disrupts the neuroprotective action of sortilin in neuronal lipid metabolism and endocannabinoid signaling

Asaro, A.; Crlo-Spiewok, A.-S.; Malik, A. R.; Rothe, M.; Schipke, C. G.; Peters, O.; Heeren, J.; Willnow, T.

10.1101/2020.01.12.903187 — neuroscience — Posted on 2020-01-14

2415 Modeling human age-associated increase in Gadd45γ expression leads to spatial recognition memory impairments in young adult mice

Brito, D. V.; Gulmez Karaca, K.; Kupke, J.; Mudlaff, F.; Zeuch, B.; Gomes, R.; Lopes, L. V.; Oliveira, A. M. M.

10.1101/2020.01.12.903112 — neuroscience — Posted on 2020-01-14

2416 Online modulation of brain hemodynamics despite stereotyped running

Bergel, A.; Tiran, E.; Deffieux, T.; Demene, C.; Tanter, M.; Cohen, I.

10.1101/2020.01.11.902932 — neuroscience — Posted on 2020-01-14

2417 Activation of Src-family kinases orchestrate secretion of flaviviruses by targeting mature progeny virions to secretory autophagosomes

Li, M. Y.; Naik, T. S.; Siu, L. Y. L.; Acuto, O.; Spooner, E.; Wang, P.; Yang, X.; Lin, Y.; Bruzzone, R.; Ashour, J.; Sanyal, S.

10.1101/2020.01.12.903062 — microbiology — Posted on 2020-01-14

2418 The fate of standing variation and new mutation under climate change

Lu, C.-Y.; Lee, C.-R.

10.1101/2020.01.12.903427 — evolutionary biology — Posted on 2020-01-14

2419 New mathematical modelling tools for co-culture experiments: when do we need to explicitly account for signalling molecules?

Jin, W.; Wang, H.; Liang, X.; Roberts, M. S.; Simpson, M. J.

10.1101/2020.01.13.905414 — biophysics — Posted on 2020-01-14

2420 SCAPP: An algorithm for improved plasmid assembly in metagenomes

Pellow, D.; Probst, M.; Furman, O.; Zorea, A.; Segal, A.; Mizrahi, I.; Shamir, R.

10.1101/2020.01.12.903252 — bioinformatics — Posted on 2020-01-14

2421 Complex genetic network underlying the convergent of Rett Syndrome like (RTT-L) phenotype in neurodevelopmental disorders

Frankel, E. S.; Dodson, J.; Sharifi, M.; Pillai, R.; Ramsey, K.; Gupta, R.; Brzezinski, M.; Venugopal, P.; Llaci, L.; Gerald, B.; Mills, G.; Belnap, N.; Sanchez-Castillo, M.; Balak, C. D.; Claasen, A. M.; Szelinger, S.; Jepsen, W. M.; Siniard, A. L.; Richholt, R.; De Both, M.; Naymik, M.; Schrauwen, I.; Piras, I. S.; Craig, D. W.; Huentelman, M. J.; Narayanan, V.; Rangasamy, S.

10.1101/2020.01.11.899658 — genomics — Posted on 2020-01-14

2422 SnpReady for Rice (SR4R) Database

Yan, J.; Zou, D.; Li, C.; Zhang, Z.; Song, S.; Wang, X.

10.1101/2020.01.11.902999 — bioinformatics — Posted on 2020-01-14

2423 An Oncometabolite Isomer Rapidly Induces A Pathophysiological Protein Modification

Bergholtz, S. E.; Briney, C. A.; Najera, S. S.; Perez, M.; Linehan, M.; Meier, J. L.

10.1101/2020.01.11.902973 — biochemistry — Posted on 2020-01-14

2424 A New Model of Genetic Variation and Evolution Evaluates Relative Impacts of Background Selections and Selective Sweeps

Gu, X.

10.1101/2020.01.11.901066 — evolutionary biology — Posted on 2020-01-14

2425 A population-level statistic for assessing Mendelian behavior of genotyping-by-sequencing data from highly duplicated genomes

Clark, L. V.; Mays, W.; Lipka, A. E.; Sacks, E. J.

10.1101/2020.01.11.902890 — bioinformatics — Posted on 2020-01-14

2426 simplePHENOTYPES: SIMulation of Pleiotropic, Linked and Epistatic PHENOTYPES

Fernandes, S. B.; Lipka, A. E.

10.1101/2020.01.11.902874 — bioinformatics — Posted on 2020-01-14

2427 Efficient replacement of long DNA fragments via non-homologous end joining at non-doding regions

Gu, S.-Y.; Li, J.; Cao, J.-B.; Bu, J.-W.; Ren, Y.-G.; Du, W.-J.; Chen, Z.-C.; Xu, C.-F.; Wang, M.-C.; Jiang, L.; Huang, C.; Du, J.-L.

10.1101/2020.01.11.902791 — genetics — Posted on 2020-01-14

2428 Size-Based Dominance Hierarchy In One Of Two Sympatric Cryptic Pacific Skinks (Emoia impar And Emoia cyanura)

Hallsten, M. E.

10.1101/2020.01.11.902866 — ecology — Posted on 2020-01-14

2429 A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity

Thai, E.; Costa, G.; Weyrich, A.; Murugan, R.; Oyen, D.; Prieto, K.; Bosch, A.; Valleriani, A.; Wu, N. C.; Pholcharee, T.; Scally, S. W.; Wilson, I. A.; Wardemann, H.; Julien, J.-P.; Levashina, E. A.

10.1101/2020.01.13.904425 — immunology — Posted on 2020-01-14

2430 ADAM17-triggered TNF signalling protects the ageing Drosophila retina from lipid droplet mediated degeneration

Muliyil, S.; Levet, C.; Düsterhöft, S.; Dulloo, I.; Cowley, S.; Freeman, M.

10.1101/2020.01.09.900209 — neuroscience — Posted on 2020-01-14

2431 A functional spiking-neuron model of activity-silent working memory in humans based on calcium-mediated short-term synaptic plasticity

Pals, M.; Stewart, T. C.; Akyurek, E. G.; Borst, J. P.

10.1101/823559 — neuroscience — Posted on 2020-01-14

2432 Pan-cancer landscape of homologous recombination deficiency

Nguyen, L.; Martens, J.; van Hoeck, A.; Cuppen, E.

10.1101/2020.01.13.905026 — cancer biology — Posted on 2020-01-14

2433 Benchmarking joint multi-omics dimensionality reduction approaches for cancer study

Cantini, L.; Zakeri, P.; Hernandez, C.; Naldi, A.; Thieffry, D.; Remy, E.; Baudot, A.

10.1101/2020.01.14.905760 — bioinformatics — Posted on 2020-01-14

2434 URMAP, an ultra fast read mapper

Edgar, R. C.

10.1101/2020.01.12.903351 — bioinformatics — Posted on 2020-01-14

2435 Transfer learning for reducing health disparity arising from data inequality

Gao, Y.; Cui, Y.

10.1101/2020.01.11.902957 — bioinformatics — Posted on 2020-01-14

2436 StereoMate: 3D Stereological Automated Analysis of Biological Structures

West, S. J.; Bonboire, D.; Bennett, D. L.

10.1101/648337 — neuroscience — Posted on 2020-01-14

2437 ComBat-Seq: batch effect adjustment for RNA-Seq count data

Zhang, Y.; Parmigiani, G.; Johnson, W. E.

10.1101/2020.01.13.904730 — bioinformatics — Posted on 2020-01-14

2438 Comparing the efficacy of cancer therapies between subgroups in basket trials

Palmer, A. C.; Plana, D.; Sorger, P.

10.1101/401620 — cancer biology — Posted on 2020-01-14

2439 A phospho-switch in the N-terminus of NRT2.1 affects nitrate uptake by controlling the interaction of NRT2.1 with NAR2.1

Li, Z.; Wu, X. N.; Jacquot, A.; Lejay, L.; Schulze, W. X.

10.1101/2020.01.08.898254 — plant biology — Posted on 2020-01-14

2440 Caspase-8 deficiency induces a switch from TLR3 induced apoptosis to lysosomal cell death in neuroblastoma cell lines

Locquet, M. A.; Ichim, G.; Dutour, A.; Lebecque, S.; Castets, M.; Weber, K.

10.1101/2020.01.13.904987 — molecular biology — Posted on 2020-01-14

2441 The effect of exercise on the protein profile of rat knee joint intra- and extra-articular ligaments

Ashraf Kharaz, Y.; Birch, H. L.; Chester, A.; Alchorne, E.; Simpson, D.; Clegg, P.; Comerford, E.

10.1101/2020.01.09.900142 — molecular biology — Posted on 2020-01-14

2442 Systematic development of peptide inhibitors targeting the CXCL12/HMGB1 interaction

Sgrignani, J.; Cecchinato, V.; Fassi, E. M. A.; Dagostino, G.; Garofalo, M.; Danelon, G.; Grazioso, G.; Uguccioni, M.; Cavalli, A.

10.1101/2019.12.18.878504 — biochemistry — Posted on 2020-01-14

2443 The evolution of paternal care: a role for microbes?

Gurevich, Y.; Lewin-Epstein, O.; Hadany, L.

10.1101/725192 — evolutionary biology — Posted on 2020-01-14

2444 Development and Characterization of an Artificial Bionic Immune Cell System based on a Synthetic Receptor Repertoire

Fu, W.; Wang, C.; Ling, Y.; Ding, M.; Lei, C.; Hu, S.

10.1101/868653 — bioengineering — Posted on 2020-01-14

2445 A possible coding for experience: ripple-like events and synaptic diversity

Ishikawa, J.; Tomokage, T.; Mitsushima, D.

10.1101/2019.12.30.891259 — animal behavior and cognition — Posted on 2020-01-14

2446 Convergent evolution and structural adaptation to the deep ocean in the eukaryotic chaperonin CCTα

Weber, A. A.-T.; Hugall, A. F.; O'Hara, T. D.

10.1101/775585 — evolutionary biology — Posted on 2020-01-14

2447 Structural basis of SALM3 dimerization and synaptic adhesion complex formation with PTPσ

Karki, S.; Shkumatov, A. V.; Bae, S.; Ko, J.; Kajander, T.

10.1101/2020.01.09.893701 — biochemistry — Posted on 2020-01-14

2448 Pursuing the limits of child survival in the most and least developed countries

Mejia-Guevara, I.; Zuo, W.; Mortensen, L. H.; Tuljapurkar, S.

10.1101/591925 — epidemiology — Posted on 2020-01-14

2449 Deletion of MOrpholino Binding Sites (DeMOBS) to Assess Specificity of Morphant Phenotypes

Cunningham, C. M.; Bellipanni, G.; Habas, R.; Balciunas, D.

10.1101/2020.01.12.903211 — developmental biology — Posted on 2020-01-14

2450 Germ plasm localisation dynamics mark distinct phases of transcriptional and post-transcriptional regulation control in primordial germ cells

D'Orazio, F. M.; Balwierz, P.; Guo, Y.; Rodriguez, B. H.; Jasiulewicz, A.; Vaquerizas, J. M.; Cairns, B.; Lenhard, B.; Mueller, F.

10.1101/2020.01.12.903336 — developmental biology — Posted on 2020-01-14

2451 sgRNA level determines CRISPRi knockdown efficiency in K562 cells

Wang, Y.; Dong, Z.; Jiang, X.; Gong, P.; Lu, J.; Wan, F.

10.1101/2020.01.12.903625 — cancer biology — Posted on 2020-01-14

2452 The peptide sensor motifs asymmetrically couple ATP hydrolysis to transport in the heterodimeric ABC transporter TmrAB

Millan, C. R.; Francis, M.; Thompson, V. F.; Thaker, T. M.; Tomasiak, T. M.

10.1101/2020.01.12.903617 — biochemistry — Posted on 2020-01-14

2453 Single-cell transcriptome analysis reveals cell-cell communication and thyrocyte diversity in the zebrafish thyroid gland

Gillotay, P.; Shankar, M. P.; Eski, S. E.; Reinhardt, S.; Kraenkel, A.; Blaesche, J.; Petzold, A.; Kesavan, G.; Lange, C.; Brand, M.; Detours, V.; Costagliola, S.; Singh, S. P.

10.1101/2020.01.13.891630 — cell biology — Posted on 2020-01-14

2454 DIP/Dpr interactions and the evolutionary design of specificity in protein families

Sergeeva, A. P.; Katsamba, P. S.; Cosmanescu, F.; Brewer, J. J.; Ahlsen, G.; Mannepalli, S.; Shapiro, L.; Honig, B.

10.1101/2020.01.13.899120 — biophysics — Posted on 2020-01-14

2455 A unifying model for the propagation of prion proteins in yeast brings insight into the prion

Lemarre, P.; Sindi, S.; Pujo-Menjouet, L.

10.1101/2020.01.13.904060 — systems biology — Posted on 2020-01-13

2456 A Paradigm for Measuring Resting State Functional Connectivity in Young Children Using fNIRS and Freeplay

Kim, J.; Ruesch, A.; Kang, N. R.; Huppert, T. J.; Kainerstorfer, J.; Thiessen, E. D.; Fisher, A. V.

10.1101/2020.01.13.904029 — neuroscience — Posted on 2020-01-13

2457 Complete genome and phylogenetic analysis of bovine papillomavirus type 15 in Southern Xinjiang dairy cow

hu, j.; Zhang, W.; Chauhan, S. S.; Shi, C.; Song, Y.; Qiu, Z.; Zhao, Y.; Wang, Z.; Cheng, L.; Zhang, Y.; Jianjun Hu, Wanqi Zhang, Surinder Singh Chauhan, Changqing Shi, Yumeng Song, Zhitao Qiu, Yubing Zhao,

10.1101/2020.01.13.904144 — microbiology — Posted on 2020-01-13

2458 In Silico Identification, Characterization and Diversity Analysis of RNAi Genes and their Associated Regulatory Elements in Sweet Orange (Citrus sinensis L)

Mosharaf, M. P.; Ahsan, M. A.; Rahman, H.; Akond, Z.; Ahmed, F. F.; Islam, M. M.; Moni, M. A.; Mollah, M. N. H.

10.1101/2020.01.13.904128 — genomics — Posted on 2020-01-13

2459 Chromatin modifiers and recombination factors promote a telomere fold-back structure, that is lost during replicative senescence

Wagner, T.; Perez-Martinez, L.; Schellhaas, R.; Barrientos-Moreno, M.; Öztürk, M.; Prado, F.; Butter, F.; Luke, B.

10.1101/2020.01.13.904086 — genetics — Posted on 2020-01-13

2460 Influence of the ecological opportunity of interaction on the structure of host-parasite networks

D'Bastiani, E.; Campiao, K. M.; Boeger, W. A.; Araujo, S. B. L.

10.1101/2020.01.13.904151 — ecology — Posted on 2020-01-13

2461 Small-scale field assessment of efficacy of the autodissemination approach against Aedes sp. in an urban area.

Mohd. Ngesom, A. M.; Othman, H.; Bahauddin, R.; Ahmad, N. W.; Lim, L. H.; Lasim, A. M.; Liang, Y.; Greenhalgh, D.; Min, J. C. S.; Sahani, M.; Hod, R.; Omar, T.

10.1101/2020.01.13.904094 — ecology — Posted on 2020-01-13

2462 Providing new insights on the byphasic lifestyle of the predatory bacterium Bdellovibrio bacteriovorus through genome-scale metabolic modeling.

Nogales, J.; Herencias, C.; Prieto, M. A.

10.1101/2020.01.13.904078 — systems biology — Posted on 2020-01-13

2463 Composition and Abundance of Drifting Fish Eggs on the Upper Reaches of Xijiang River, China, after the Formation of the Cascade Reservoirs

Gao, M.; Wu, Z.; Tan, X.; Huang, L.; Huang, H.; Liu, H.

10.1101/2020.01.13.904110 — ecology — Posted on 2020-01-13

2464 Comparative primary paediatric nasal epithelial cell culture differentiation and RSV-induced cytopathogenesis following culture in two commercial media.

Broadbent, L.; Manzoor, S.; Zarcone, M.; Barabas, J.; Shields, M.; Saglani, S.; Lloyd, C. M.; Bush, A.; Custovic, A.; Ghazal, P.; Gore, M.; Marsland, B.; Roberts, G.; Schwarze, J.; Turner, S.; Power, U. F.

10.1101/2020.01.13.904037 — cell biology — Posted on 2020-01-13

2465 Function and evolution of B-Raf loop dynamics relevant to cancer recurrence under drug inhibition

Babbitt, G. A.; Lynch, M. L.; McCoy, M.; Fokoue, E. P.; Hudson, A. O.

10.1101/2020.01.13.904052 — biophysics — Posted on 2020-01-13

2466 Comparison of de-duplication methods used by WHO Global Antimicrobial Resistance Surveillance System (GLASS) and Japan Nosocomial Infections Surveillance (JANIS) in the surveillance of antimicrobial resistance

Kajihara, T.; Yahara, K.; Stelling, J.; Eremin, S. R.; Tornimbene, B.; Thamlikitkul, V.; Hirabayashi, A.; Anzai, E.; Wakai, T.; Matsunaga, N.; Hayakawa, K.; Ohmagari, N.; Sugai, M.; Shibayama, K.

10.1101/2020.01.13.904136 — microbiology — Posted on 2020-01-13

2467 Disease mutation study identifies essential residues for phosphatidylserine flippase ATP11A

Sun, K.; Tian, W.; Liu, W.; Yang, Y.; Zhu, X.

10.1101/2020.01.13.904045 — biochemistry — Posted on 2020-01-13

2468 Multiple retrospective analysis of survival and evaluation of cardiac death predictors in a population of dogs affected by degenerative mitral valve disease in ACVIM class C treated with different therapeutic protocols

BAGARDI, M.; Locatelli, C.; Zanaboni, A.; Galizzi, A.; Malchiodi, D.; Brambilla, P. G.

10.1101/2020.01.13.904102 — pathology — Posted on 2020-01-13

2469 Diverse genetic origins of medieval steppe nomad conquerors - a response to Mikheyev et al. (2019)

Elhaik, E.

10.1101/2020.01.06.885103 — genomics — Posted on 2020-01-13

2470 Exploring the potential genetic heterogeneity in the incidence of hoof and leg disorders in Austrian Fleckvieh and Braunvieh cattle

Kosinska-Selbi, B.; Suchocki, T.; Egger-Danner, C.; Schwarzenbacher, H.; Fraszczak, M.; Szyda, J.

10.1101/2020.01.11.902767 — zoology — Posted on 2020-01-13

2471 Deformed Wing Virus spillover from honey bees to bumble bees: a reverse genetic study.

Gusachenko, O. N.; Woodford, L.; Balbirnie-Cumming, K.; Ryabov, E. V.; Evans, D. J.

10.1101/2019.12.18.880559 — microbiology — Posted on 2020-01-13

2472 Avid binding by B cells to the Plasmodium circumsporozoite protein repeat suppresses responses to protective subdominant epitopes

Lewis, F. J.; Chatterjee, D.; Kaczmarski, J.; Gao, X.; Cai, Y.; McNamara, H. A.; Sutton, H. J.; Jackson, C. J.; Cockburn, I. A.

10.1101/2020.01.12.903682 — immunology — Posted on 2020-01-13

2473 Multi-Object Tracking in Heterogeneous environments (MOTHe) for animal space-use studies

Rathore, A.; Sharma, A.; Sharma, N.; Guttal, V.

10.1101/2020.01.10.899989 — ecology — Posted on 2020-01-13

2474 Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

Arai, S.; Chen, S.; Xie, L.; Balk, S.

10.1101/2020.01.12.903369 — cancer biology — Posted on 2020-01-13

2475 Method to identify physical, chemical and biological factors that trigger Bcl-xL-mediated apoptosis

Ianevski, A.; Kulesskiy, E.; Krpina, K.; Lou, G.; Aman, Y.; Bugai, A.; Aasumets, K.; Akimov, Y.; Bulanova, D.; Gildemann, K.; Arutyunyan, A. F.; Susova, O. Y.; Zhuze, A. L.; Oksenych, V.; Lysvand, H.; Gerhold, J.; Bjoras, M.; Waage, A.; Johansen, P.; Heckman, C.; Fang, E. F.; Kainov, D. E.

10.1101/2020.01.13.904714 — cancer biology — Posted on 2020-01-13

2476 Recognition of cellular RNAs by the S9.6 antibody creates pervasive artefacts when imaging RNA:DNA hybrids

Chedin, F.; Smolka, J. A.; Sanz, L. A.; Hartono, S. R.

10.1101/2020.01.11.902981 — molecular biology — Posted on 2020-01-13

2477 Shotgun Proteomics of non-depleted and depleted hemolymph of human Schistosomiasis snail vector; Biomphalaria glabrata, revealed vital immune related proteins

Otarigho, B.

10.1101/2020.01.12.903708 — immunology — Posted on 2020-01-13

2478 A broad and potent H1-specific human monoclonal antibody produced in plants prevents influenza virus infection and transmission in guinea pigs

Park, J.-G.; Ye, C.; Piepenbrink, M.; Nogales, A.; Wang, H.; Shuen, M.; Meyers, A.; Martinez-Sobrido, L.; Kobie, J.

10.1101/2020.01.13.902841 — immunology — Posted on 2020-01-13

2479 Cancer-associated fibroblast compositions change with breast cancer progression linking S100A4 and PDPN ratios with clinical outcome

Friedman, G.; Levi-Galibov, O.; David, E.; Bornstein, C.; Giladi, A.; Dadiani, M.; Mayo, A.; Halperin, C.; Pevsner-Fischer, M.; Lavon-Pashot, H.; Nevo, R.; Stein, Y.; Ali, H. R.; Caldas, C.; Nili-Gal-Yam, E.; Alon, U.; Amit, I.; Scherz-Shouval, R.

10.1101/2020.01.12.903039 — cancer biology — Posted on 2020-01-13

2480 Systems level profiling of arginine starvation reveals MYC and ERK adaptive metabolic reprogramming

Brashears, C. B.; Rathore, R.; Schultze, M.; Ehrhardt, W. R.; Tzeng, S.-C.; Van Tine, B. A.; Held, J. M.

10.1101/2020.01.13.904011 — cancer biology — Posted on 2020-01-13

2481 Biomarker-guided treatment strategies for ovarian cancer identified from a heterogeneous panel of patient-derived tumor xenografts

Palmer, A. C.; Plana, D.; Gao, H.; Korn, J. M.; Yang, G.; Green, J.; Zhang, X.; Velazquez, R.; McLaughlin, M. E.; Ruddy, D. A.; Kowal, C.; Goldovitz, J.; Bullock, C.; Rivera, S.; Rakiec, D.; Elliott, G.; Fordjour, P.; Meyer, R.; Loo, A.; Kurth, E.; Engelman, J. A.; Bitter, H.; Sellers, W. R.; Sorger, P. K.; Williams, J. A.

10.1101/2020.01.08.898734 — cancer biology — Posted on 2020-01-13

2482 In Silico Analysis of Some Phytochemicals as Potential Anti-cancer Agents Targeting Cyclin Dependent Kinase-2, Human Topoisomerase IIa and Vascular Endothelial Growth Factor Receptor-2

Sarkar, B.; Ullah, M. A.; Islam, S. S.

10.1101/2020.01.10.901660 — bioinformatics — Posted on 2020-01-13

2483 Motor imagery practice during arm-immobilization benefits sensorimotor cortical functions and plasticity-related sleep features

Debarnot, U.; Perrault, A. A.; Sterpenich, V. A.; Legendre, G.; Huber, C.; Guillot, A.; Schwartz, S.

10.1101/828889 — neuroscience — Posted on 2020-01-13

2484 Precise coupling of the thalamic head-direction system to hippocampal ripples.

Viejo, G.; Peyrache, A.

10.1101/809657 — neuroscience — Posted on 2020-01-13

2485 Genome-Wide Search for Candidate Drivers of Adaptation Reveals Genes Enriched for Shifts in Purifying Selection (SPurS)

Popejoy, A. B.; Domanska, D.; Thomas, J. H.

10.1101/2020.01.11.902759 — evolutionary biology — Posted on 2020-01-13

2486 Functional MRI Investigation on Paradigmatic and Syntagmatic Lexical Semantic Processing

Ying, S.; Ploux, S.

10.1101/2020.01.11.899831 — bioinformatics — Posted on 2020-01-13

2487 Systematic development of peptide inhibitors targeting the CXCL12/HMGB1 interaction

Sgrignani, J.; Cecchinato, V.; Fassi, E. M. A.; Dagostino, G.; Garofalo, M.; Danelon, G.; Grazioso, G.; Uguccioni, M.; Cavalli, A.

10.1101/2019.12.18.878504 — biochemistry — Posted on 2020-01-13

2488 In-depth secretome analysis of Puccinia striiformis f. sp. tritici in infected wheat uncovers effector functions

Ozketen, A. C.; Andac, A.; Dagvadorj, B.; Demiralay, B.; Akkaya, M. S.

10.1101/2020.01.11.897884 — microbiology — Posted on 2020-01-13

2489 Novel intramolecular base-pairing of the U8 snoRNA underlies a Mendelian form of cerebral small vessel disease

Badrock, A. P.; Uggenti, C.; Wacheul, L.; Crilly, S.; Jenkinson, E. M.; Rice, G. I.; Kasher, P. R.; Lafontaine, D. L. J.; Crow, Y. J.; O'Keefe, R. T.

10.1101/2019.12.12.874594 — genetics — Posted on 2020-01-13

2490 Conformational distributions of isolated myosin motor domains encode their mechanochemical properties

Porter, J. R.; Meller, A.; Zimmerman, M. I.; Greenberg, M. J.; Bowman, G. R.

10.1101/2019.12.16.878264 — biophysics — Posted on 2020-01-13

2491 Ares-GT: design of guide RNAs targeting multiple genes for CRISPR-Cas experiments

Minguet, E. G.

10.1101/2020.01.08.898742 — bioinformatics — Posted on 2020-01-13

2492 SVJedi: Genotyping structural variations with long reads

Lecompte, L.; Peterlongo, P.; Lavenier, D.; Lemaitre, C.

10.1101/849208 — bioinformatics — Posted on 2020-01-13

2493 A functional cortical network for sensorimotor sequence generation

Xu, D.; Chen, Y.; Delgado, A. M.; Hughes, N. C.; Zhang, L.; Dong, M.; O'Connor, D. H.

10.1101/783050 — neuroscience — Posted on 2020-01-13

2494 An Enzymatic Active Site Embedded in a DNA Nanostructure

Kekic, T.; Ahmadi, Y.; Barisic, I.

10.1101/804518 — synthetic biology — Posted on 2020-01-13

2495 Spectral Hallmark of Auditory-Tactile Interactions in the Mouse Somatosensory Cortex

Zhang, M.; Kwon, S. E.; Ben-Johny, M.; O'Connor, D. H.; Issa, J. B.

10.1101/668319 — neuroscience — Posted on 2020-01-13

2496 The nervous system is the major target for Gold nanoparticle: Evidence from RNA sequencing data of C. elegans

Wang, L.; Mo, J.; Li, S.; Sun, N.; Yang, B.

10.1101/699785 — neuroscience — Posted on 2020-01-13

2497 A Non-negative Measure Of Feature-specific Information Transfer Between Neural Signals

Bim, J.; De Feo, V.; Chicharro, D.; Bieler, M.; Hanganu-Opatz, I. L.; Brovelli, A.; Panzeri, S.

10.1101/758128 — neuroscience — Posted on 2020-01-13

2498 Climate change negatively impacts dominant microbes in the sediments of a High Arctic lake

Colby, G. A.; Ruuskanen, M.; St. Pierre, K.; St.Louis, V.; Poulain, A.; Aris-Brosou, S.

10.1101/705178 — microbiology — Posted on 2020-01-13

2499 Tumor fitness, immune exhaustion and clinical outcomes: impact of immune checkpoint inhibitors

Bubie, A.; Kozlova, E. G.; Akers, N.; Villanueva, A.; Losic, B.

10.1101/679886 — cancer biology — Posted on 2020-01-13

2500 Allosteric Inhibition of CRISPR-Cas9 by Bacteriophage-derived Peptides

Cui, Y.; Wang, S.; Chen, J.; Li, J.; Chen, W.; Wang, S.; Meng, B.; Zhu, W.; Zhang, Z.; Yang, B.; Jiang, B.; Yang, G.; Ma, P.; Liu, J.

10.1101/642538 — genomics — Posted on 2020-01-13

2501 Systematic detection of divergent brain protein-coding genes in human evolution and their roles in cognition

Dumas, G.; Malesys, S.; Bourgeron, T.

10.1101/658658 — genetics — Posted on 2020-01-13

2502 Mitochondria-ER contacts in reactive astrocytes coordinate local perivascular domains to promote vascular remodelling

Goebel, J.; Engelhardt, E.; Pelzer, P.; Sakthivelu, V.; Jahn, H. M.; Jevtic, M.; Folz-Donahue, K.; Kukat, C.; Schauss, A.; Frese, C.; Giavalisco, P.; Ghanem, A.; Conzelmann, K.-K.; Motori, E.; Bergami, M.

10.1101/657999 — cell biology — Posted on 2020-01-13

2503 Retrospective Ensemble Docking of Allosteric Modulators in an Adenosine G-Protein-Coupled Receptor

Bhattarai, A.; Wang, J.; Miao, Y.

10.1101/2020.01.11.902809 — biophysics — Posted on 2020-01-13

2504 Periprotein membrane lipidomics and the role of lipids in transporter function in yeast

van't Klooster, J.; Cheng, T.-Y.; Sikkema, H. R.; Jeucken, A.; Moody, B.; Poolman, B.

10.1101/2020.01.12.903161 — biochemistry — Posted on 2020-01-13

2505 Identification of QTL for leaf angle at canopy-wide levels in maize

Tang, D.; Chen, Z.; JIang, Q.; Ni, J.; Li, P.; Wang, L.; Zhou, J.; Li, C.; Liu, J.

10.1101/499665 — plant biology — Posted on 2020-01-13

2506 Chromatin arranges in chains of mesoscale domains with nanoscale functional topography independent of cohesin

Miron, E.; Oldenkamp, R.; Brown, J. M.; Pinto, D. M.; Xu, C. S.; Faria, A. R.; Shaban, H. A.; Rhodes, J. D.; Innocent, C.; de Ornellas, S.; Hess, H.; Buckle, V.; Schermelleh, L.

10.1101/566638 — genomics — Posted on 2020-01-13

2507 Natural copy number differences of tandemly repeated small nucleolar RNAs in the Prader-Willi syndrome genomic region regulate individual behavioral responses in mammals

Keshavarz, M.; Krebs, R.; Refki, P. N.; Savriama, Y.; Zhang, Y. N.; Guenther, A.; Brückl, T. M.; Binder, E.; Tautz, D.

10.1101/476010 — evolutionary biology — Posted on 2020-01-13

2508 Morphological facilitators for vocal learning explored through the syrinx anatomy of a basal hummingbird

Monte, A.; Cerwenka, A.; Ruthensteiner, B.; Gahr, M.; During, D. N.

10.1101/2020.01.11.902734 — evolutionary biology — Posted on 2020-01-13

2509 Embryonic signals perpetuate polar-like trophoblast stem cells and pattern the blastocyst axis.

Frias Aldeguer, J.; Kip, M.; Vivie, J.; Li, L.; Alemany, A.; Korving, J.; Darmis, F.; van Oudenaarden, A.; Geijsen, N.; Rivron, N. C.

10.1101/510362 — developmental biology — Posted on 2020-01-13

2510 Robust and Bright Genetically Encoded Fluorescent Markers for Highlighting Structures and Compartments in Mammalian Cells

Chertkova, A. O.; Mastop, M.; Postma, M.; van Bommel, N.; van der Niet, S.; Batenburg, K. L.; Joosen, L.; Gadella, T. W. J.; Okada, Y.; Goedhart, J.

10.1101/160374 — cell biology — Posted on 2020-01-13

2511 The role of startle fluctuation and non-response startle reflex in tracking amygdala dynamics

Liu, M.; Amey, R. C.; Magerman, A.; Scott, M.; Forbes, C.

10.1101/2020.01.12.903526 — neuroscience — Posted on 2020-01-13

2512 The OptoGenBox - a device for long-term optogenetics in C. elegans

Busack, I.; Jordan, F.; Sapir, P.; Bringmann, H.

10.1101/2020.01.13.903948 — neuroscience — Posted on 2020-01-13

2513 Basal forebrain rhythmicity is modulated by the exploration phase of novel environments

Santos-Pata, D.; Verschure, P. F.

10.1101/2020.01.11.902742 — neuroscience — Posted on 2020-01-13

2514 Neuronal firing and waveform alterations through ictal recruitment in humans

Merricks, E. M.; Smith, E. H.; Emerson, R. G.; Bateman, L. M.; McKhann, G. M.; Goodman, R. R.; Sheth, S. A.; Greger, B.; House, P. A.; Trevelyan, A. J.; Schevon, C. A.

10.1101/2020.01.11.902817 — neuroscience — Posted on 2020-01-13

2515 Complement and coagulation cascades are potentially involved in dopaminergic neurodegeneration in alpha-synuclein-based mouse models of Parkinson's disease

Ma, S.-X.; Kim, D.; Xiong, Y.; Kwon, S.-H.; Brahmachari, S.; Kim, S.; Kam, T.-I.; Nirujogi, R. S.; Kwon, S. H.; Dawson, V. L.; Dawson, T. M.; Pandey, A.; Na, C. H.; Ko, H. S.

10.1101/2020.01.11.900886 — neuroscience — Posted on 2020-01-13

2516 Calcium-independent astrocytic lipid release modulates neuronal activity through Kv channels

Wang, F.; Bradshaw, H. B.; Jablonska, B.; Pena, S. E.; Xavier, J.; Gong, S.; Li, B.; Chandler-Militello, D.; Bekar, L. K.; Smith, N. A.

10.1101/2020.01.12.903393 — neuroscience — Posted on 2020-01-13

2517 Identification of a Δ11 desaturase from the arbuscular mycorrhizal fungus Rhizophagus irregularis

Cheeld, H.; Bhutada, G.; Beaudoin, F.; Eastmond, P. J.

10.1101/2020.01.13.903815 — microbiology — Posted on 2020-01-13

2518 Differential contributions of synaptic and intrinsic inhibitory currents to parsing via flexible phase-locking in neural oscillators

Pittman-Polletta, B. R.; Wang, Y.; Stanley, D. A.; Schroeder, C. E.; Whittington, M. A.; Kopell, N. J.

10.1101/2020.01.11.902858 — neuroscience — Posted on 2020-01-13

2519 Functional variants within the 5UTR support reduced exon usage as a molecular mechanism underlying the quantitative trait gene Hnrnph1 for reduced methamphetamine sensitivity

Ruan, Q. T.; Yazdani, N.; Reed, E. R.; Beierle, J. A.; Peterson, L. P.; Luttik, K. P.; Szumlinski, K. K.; Johnson, W. E.; Ash, P. E. A.; Wolozin, B.; Bryant, C. D.

10.1101/2020.01.11.902908 — neuroscience — Posted on 2020-01-13

2520 Chemogenetic analysis of how receptors for short chain fatty acids regulate the gut-brain axis

Tobin, A. B.; Barki, N.; Bolognini, D.; Borjesson, U.; Jenkins, L.; Riddell, J.; Hughes, D. I.; Ulven, T.; Hudson, B. D.; Ulven, E. R.; Dekker, N.; Milligan, G.

10.1101/2020.01.11.902726 — pharmacology and toxicology — Posted on 2020-01-13

2521 Two-step mechanism of J-domain action in driving Hsp70 function

Tomiczek, B.; Delewski, W.; Nierzwicki, L.; Stolarska, M.; Grochowina, I.; Schilke, B.; Dutkiewicz, R.; Uzarska, M. A.; Ciesielski, S. J.; Czub, J.; Craig, E. A.; Marszalek, J.

10.1101/2020.01.13.901538 — molecular biology — Posted on 2020-01-13

2522 A practical staging atlas to study embryonic development of Octopus vulgaris under controlled laboratory conditions

Deryckere, A.; Styfhals, R.; Vidal, E. A. G.; Almansa, E.; Seuntjens, E.

10.1101/2020.01.13.903922 — developmental biology — Posted on 2020-01-13

2523 Surface topography is a context-dependent activator of TGF-β signaling in mesenchymal stem cells

Vermeulen, S.; Roumans, N.; Honig, F.; Carlier, A.; Hebels, D. G.; Dede Eren, A.; ten Dijcke, P.; Vasilevich, A.; de Boer, J.

10.1101/2020.01.13.903195 — cell biology — Posted on 2020-01-13

2524 Targeting Aryl Hydrocarbon Receptor with small molecule, 1'H-indole-3'-carbonyl -thiazole-4-carboxylic acid methyl ester blocked human glioma cell invasion via MYH9

Zhao, l. j.; Shu, Q. t.; Sun, H.; Ma, Y. l.; Kang, D. d.; Zhao, Y. t.; Lu, J.; Gong, P.; Yang, F.; Wan, f.

10.1101/2020.01.13.903674 — cell biology — Posted on 2020-01-13

2525 SPARC promotes insulin secretion through down-regulation of RGS4 protein in pancreatic beta-cells

Hu, L.; He, F.; Huang, M.; Zhao, Q.; Cheng, L.; Said, N.; Zhou, Z.; Liu, F.; Dai, Y.-S.

10.1101/2020.01.11.902916 — cell biology — Posted on 2020-01-13

2526 Division of labor between YAP and TAZ in non-small cell lung cancer

Shaked, M.; Oren, M.; Dassa, B.; Sinha, S.; Di Agostino, S.; Azuri, I.; Aylon, Y.; Blandino, G.; Ruppin, E.

10.1101/2020.01.12.894733 — cancer biology — Posted on 2020-01-13

2527 Comparison of CRISPR and marker based methods for the engineering of phage T7

Grigonyte, A. M.; Harrison, C.; MacDonald, P. R.; Montero-Blay, A.; Tridgett, M.; Duncan, J.; Sagona, A.; Constantinidou, C.; Jaramillo, A.; Millard, A. D.

10.1101/2020.01.12.903492 — molecular biology — Posted on 2020-01-13

2528 Comparison of cellular Na+ assays by flow fluorometry with ANG-2 and flame emission: Pitfalls in using ionophores for calibrating fluorescent probes

Yurinskaya, V.; Aksenov, N.; Moshkov, A.; Goryachaya, T.; Vereninov, A. A.

10.1101/2020.01.13.904003 — cell biology — Posted on 2020-01-13

2529 Optimizing the PBS1 Decoy System to Confer Resistance to Potyvirus Infection in Arabidopsis and Soybean

Pottinger, S. E.; Bak, A.; Margets, A.; Helm, M.; Tang, L.; Casteel, C. L.; Innes, R. W.

10.1101/2020.01.12.903575 — plant biology — Posted on 2020-01-13

2530 Palmitvaccenic acid (Δ11-cis-hexadecenoic acid) is synthesized by an OLE1-like desaturase in the arbuscular mycorrhiza fungus Rhizophagus irregularis

Brands, M.; Cahoon, E.; Doermann, P.

10.1101/2020.01.13.901264 — plant biology — Posted on 2020-01-13

2531 Beyond the forest-grassland dichotomy: the gradient-like organization of habitats in forest-steppes

Erdos, L.; Torok, P.; Szitar, K.; Batori, Z.; Tolgyesi, C.; Kiss, P. J.; Bede-Fazekas, A.; Kroel-Dulay, G.

10.1101/2020.01.12.903344 — plant biology — Posted on 2020-01-13

2532 Impact of a resistance gene against a fungal pathogen on the plant host residue microbiome: the case of the Leptosphaeria maculans-Brassica napus pathosystem

Kerdraon, L.; Barret, M.; Balesdent, M.-H.; Suffert, F.; Laval, V.

10.1101/2020.01.13.903765 — microbiology — Posted on 2020-01-13

2533 Germination response of invasive plants to soil burial depth and litter accumulation is species specific

Sonkoly, J.; Valko, O.; Balogh, N.; Godo, L.; Kelemen, A.; Kiss, R.; Miglecz, T.; Toth, E.; Toth, K.; Tothmeresz, B.; Török, P.

10.1101/2020.01.13.904227 — ecology — Posted on 2020-01-13

2534 New intranuclear symbiotic bacteria from macronucleus of Paramecium putrinum -- Candidatus Gortzia yakutica

Beliavskaia, A. Y.; Garushyants, S.; Logacheva, M.; Gong, J.; Zou, S.; Gelfand, M.; Rautian, M.

10.1101/2020.01.13.895557 — microbiology — Posted on 2020-01-13

2535 Designing and implementing programmable depletion in sequencing libraries with DASHit

Dynerman, D.; Lyden, A.; Quan, J.; Caldera, S.; McGeever, A.; Dimitrov, B.; King, R.; Cirola, G.; Tan, M.; Sit, R.; van den Berge, M.; Kerstjens, H. A. M.; Faiz, A.; Christenson, S.; Langelier, C.; DeRisi, J.; Crawford, E. D.

10.1101/2020.01.12.891176 — microbiology — Posted on 2020-01-13

2536 A possible coding for experience: ripple-like events and synaptic diversity

Ishikawa, J.; Tomokage, T.; Mitsushima, D.

10.1101/2019.12.30.891259 — animal behavior and cognition — Posted on 2020-01-13

2537 Neuronal responses in posterior parietal cortex during learning of implied serial order

Munoz, F.; Jensen, G.; Kennedy, B. C.; Alkan, Y.; Terrace, H. S.; Ferrera, V. P.

10.1101/689133 — neuroscience — Posted on 2020-01-13

2538 Prediction of drug-target binding affinity using graph neural networks

Nguyen, T.; Le, H.; Quinn, T. P.; Le, T.; Venkatesh, S.

10.1101/684662 — bioinformatics — Posted on 2020-01-13

2539 Essential Metabolic Routes as a Way to ESKAPE from Antibiotic Resistance

Barra, A. L. C.; Dantas, L. d. O. C.; Morao, L. G.; Gutierrez, R. F.; Polikarpov, I.; Wrenger, C.; Nascimento, A. S.

10.1101/817015 — biochemistry — Posted on 2020-01-13

2540 Comprehensive Classification of the RNase H-like domain-containing Proteins in Plants

Li, S.; Liu, K.; Sun, Q.

10.1101/572842 — plant biology — Posted on 2020-01-13

2541 A New Tree-Based Methodological Framework to Infer the Evolutionary History of Mesopolyploid Lineages: An Application to the Brassiceae Tribe (Brassicaceae).

Henocq, L.; Gallina, S.; Schmitt, E.; Castric, V.; Vekemans, X.; Poux, C.

10.1101/2020.01.09.900571 — evolutionary biology — Posted on 2020-01-13

2542 Simplitigs as an efficient and scalable representation of de Bruijn graphs

Brinda, K.; Baym, M.; Kucherov, G.

10.1101/2020.01.12.903443 — bioinformatics — Posted on 2020-01-12

2543 A population of stress-like cancer cells in melanoma promotes tumorigenesis and confers drug resistance

Baron, M.; Tagore, M.; Hunter, M. V.; Kim, I. S.; Moncada, R.; Yan, Y.; Campbell, N. R.; White, R. M.; Yanai, I.

10.1101/396622 — cancer biology — Posted on 2020-01-12

2544 No effect of monetary reward in a visual working memory task

van den Berg, R.; Zou, Q.; Ma, W. J.

10.1101/767343 — animal behavior and cognition — Posted on 2020-01-12

2545 Phase Transition of RNA-protein Complexes into Ordered Hollow Condensates

Alshareedah, I.; Moosa, M. M.; Raju, M.; Potoyan, D. A.; Banerjee, P. R.

10.1101/2020.01.10.902353 — biophysics — Posted on 2020-01-12

2546 Size regulation of multiple organelles competing for a shared subunit pool

Banerjee, D. S.; Banerjee, S.

10.1101/2020.01.11.902783 — biophysics — Posted on 2020-01-12

2547 Mucoidy, a general mechanism for maintaining lytic phage in populations of bacteria

Levin, B. R.; Chaudhry, W. N.; Lee, E.; Worthy, A.; Weiss, Z.; Grabowicz, M.; Vega, N.

10.1101/775056 — microbiology — Posted on 2020-01-12

2548 An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis

Xiang, G.; Keller, C. A.; Heuston, E. F.; Giardine, B. M.; An, L.; Wixom, A. Q.; Miller, A.; Cockburn, A.; Sauria, M. E. G.; Weaver, K.; Lichtenberg, J.; Gottgens, B.; Li, Q.; Bodine, D.; Mahony, S.; Taylor, J.; Blobel, G. A.; Weiss, M. J.; Cheng, Y.; Yue, F.; Hughes, J.; Higgs, D. R.; Zhang, Y.; Hardison, R. C.

10.1101/731729 — genomics — Posted on 2020-01-12

2549 Ecotone formation through ecological niche construction: the role of biodiversity and species interactions

Liautaud, K.; Barbier, M.; Loreau, M.

10.1101/740282 — ecology — Posted on 2020-01-12

2550 Live cell single molecule tracking and localization microscopy of bioorthogonally labeled plasma membrane proteins

König, A. I.; Sorkin, R.; Alon, A.; Nachmias, D.; Dhara, K.; Brand, G.; Yifrach, O.; Roichman, Y.; Arbely, E.; Elia, N.

10.1101/660118 — biophysics — Posted on 2020-01-12

2551 Experimental manipulation of selfish genetic elements links genes to microbial community function

Quistad, S.; Doulcier, G.; Rainey, P. B.

10.1101/608752 — microbiology — Posted on 2020-01-12

2552 MAUI-seq: Metabarcoding using amplicons with unique molecular identifiers to improve error correction

Fields, B.; Moeskjaer, S.; Friman, V.-P.; Andersen, S. U.; Young, J. P. W.

10.1101/538587 — ecology — Posted on 2020-01-12

2553 Mechanisms of Igf2 inhibition in thymic epithelial cells infected by coxsackievirus CV-B4

Michaux, H.; Halouani, A.; Trussart, C.; Renard, C.; Jaïdane, H.; Martens, H.; Hober, D.; Geenen, V.

10.1101/2020.01.10.902684 — microbiology — Posted on 2020-01-12

2554 Visible Light Plasmon Excitation of Silver Nanoparticles Against Antibiotic-Resistant Pseudomonas aeruginosa

Trivella, R.; Petri, M.; Valencia, E.-Y.; Camargo, P. H.; Torresi, S.; Spira, B.

10.1101/2020.01.10.902676 — microbiology — Posted on 2020-01-12

2555 Neural circuit mechanism for generating categorical representations

Mahajan, N. R.; Mysore, S. P.

10.1101/2019.12.24.887810 — neuroscience — Posted on 2020-01-12

2556 Deficiency of Norepinephrine Transmission In Brain Contributed To Seizure-Induced Respiratory Arrest In the DBA/1 Mouse SUDEP Model

Shen, Y.; MA, H.; Lu, H.; Zhao, H.; Sun, J.; Cheng, Y.; Shen, Y.; Zhou, Y. D.; Zhang, H.

10.1101/865691 — neuroscience — Posted on 2020-01-12

2557 Causal relationships between blood lipids and depression phenotypes: A Mendelian randomization analysis

So, H.-C.; Chau, C. K.-l.; Cheng, Y.-y.; Sham, P. C.

10.1101/363119 — genetics — Posted on 2020-01-12

2558 NASQAR: A web-based platform for High-throughput sequencing data analysis and visualization

Yousif, A.; Drou, N.; Rowe, J.; Khalfan, M.; Gunsalus, K.

10.1101/709980 — bioinformatics — Posted on 2020-01-12

2559 A Genetically Encoded Trimethylsilyl 1D 1H-NMR Probe for Conformation Change in Large Membrane Protein Complexes

Liu, Q.; He, Q.-t.; Lyu, X.-x.; Yang, F.; Zhu, Z.-l.; Xiao, P.; Yang, Z.; Zhang, F.; Yang, Z.-y.; Wang, X.-y.; Sun, P.; Wang, Q.-w.; Qu, C.-x.; Gong, Z.; Lin, J.-Y.; Xu, Z.; Song, S.-l.; Huang, S.-m.; Guo, S.-c.; Han, M.-j.; Zhu, K.-k.; Chen, X.; Kahsai, A. W.; Xiao, K.-H.; Kong, W.; Yu, X.; Ruan, K.; Li, F.-h.; Niu, X.-g.; Jin, C.-w.; Wang, J.; Sun, J.

10.1101/2019.12.18.873729 — biochemistry — Posted on 2020-01-12

2560 Deep, soft, and dark sounds induce autonomous sensory meridian response

Koumura, T.; Nakatani, M.; Liao, H.-I.; Kondo, H. M.

10.1101/2019.12.28.889907 — neuroscience — Posted on 2020-01-12

2561 Masculinity and the mechanisms of human self-domestication

Gleeson, B. T.

10.1101/143875 — evolutionary biology — Posted on 2020-01-12

2562 Design Principles of Lambda's Lysis/Lysogeny Decision vis-a-vis Multiplicity of Infection

Wadhwa, D.

10.1101/146308 — systems biology — Posted on 2020-01-12

2563 Cortical music selectivity does not require musical training

Boebinger, D. L.; Norman-Haignere, S. V.; McDermott, J. H.; Kanwisher, N.

10.1101/2020.01.10.902189 — neuroscience — Posted on 2020-01-11

2564 Slow drift of neural activity as a signature of impulsivity in macaque visual and prefrontal cortex

Cowley, B. R.; Snyder, A. C.; Acar, K.; Williamson, R. C.; Yu, B. M.; Smith, M. A.

10.1101/2020.01.10.902403 — neuroscience — Posted on 2020-01-11

2565 A 4-base pair core-enclosing helix in telomerase RNA is essential and binds to the TERT catalytic protein subunit

Mefford, M. A.; Hass, E. P.; Zappulla, D. C.

10.1101/2020.01.10.902601 — molecular biology — Posted on 2020-01-11

2566 Ferrosomes are iron storage organelles formed by broadly conserved gene clusters in bacteria and archaea

Grant, C. R.; Komeili, A.

10.1101/2020.01.10.902569 — microbiology — Posted on 2020-01-11

2567 Machine learning classification can reduce false positives in structure-based virtual screening

Adeshina, Y.; Deeds, E. J.; Karanicolas, J.

10.1101/2020.01.10.902411 — bioinformatics — Posted on 2020-01-11

2568 Fully Automated Peptide Mapping Protocol for Multi-Attribute Method by Liquid Chromatography-Tandem Mass Spectroscopy with a High-Throughput Robotic Liquid Handling System

Qian, C.; Niu, B.; Jimenez, R. B.; Wang, J.; Albarghouthi, M.; Chen, X.

10.1101/2020.01.10.902338 — biochemistry — Posted on 2020-01-11

2569 Reconstruction of motor control circuits in adult Drosophila using automated transmission electron microscopy

Maniates-Selvin, J. T.; Hildebrand, D. G. C.; Graham, B. J.; Kuan, A. T.; Thomas, L. A.; Nguyen, T.; Buhmann, J.; Azevedo, A. W.; Shanney, B. L.; Funke, J.; Tuthill, J. C.; Lee, W.-C. A.

10.1101/2020.01.10.902478 — neuroscience — Posted on 2020-01-11

2570 Contrasting population genetics of cattle- and buffalo- derived Theileria annulata causing tropical theileriosis

Chaudhry, U.; Ali, Q.; Zheng, L.; Rashid, I.; Shabbir, M. Z.; Nauman, M.; Ashraf, K.; Evans, M.; Rafiq, S.; Oneeb, M.; Morrison, I.; Morrison, L.; Sargison, N. D.

10.1101/2020.01.10.902031 — genetics — Posted on 2020-01-11

2571 An image-computable model of human visual shape similarity

Morgenstern, Y.; Hartmann, F.; Schmidt, F.; Tiedemann, H.; Prokott, E.; Maiello, G.; Fleming, R.

10.1101/2020.01.10.901876 — neuroscience — Posted on 2020-01-11

2572 Scaling of information in large neural populations reveals signatures of information-limiting correlations

Kafashan, M.; Jaffe, A.; Chettih, S. N.; Nogueira, R.; Arandia-Romero, I.; Harvey, C. D.; Moreno-Bote, R.; Drugowitsch, J.

10.1101/2020.01.10.902171 — neuroscience — Posted on 2020-01-11

2573 Detection of urease and carbonic anhydrase activity using a rapid and economical field test to assess microbially-induced carbonate precipitation

Medina Ferrer, F.; Hobart, K.; Bailey, J. V.

10.1101/2020.01.10.902379 — microbiology — Posted on 2020-01-11

2574 Bariatric surgery reveals a gut-restricted TGR5 agonist that exhibits anti-diabetic effects

Chaudhari, S. N.; Harris, D. A.; Aliakbarian, H.; Henke, M. T.; Subramaniam, R.; Vernon, A. H.; Tavakkoli, A.; Sheu, E. G.; Devlin, A. S.

10.1101/2020.01.10.902346 — biochemistry — Posted on 2020-01-11

Wu, Z.; Kavanova, M.; Hickman, L.; Lin, F.; Buckley, M. J.

10.1101/2020.01.10.901975 — animal behavior and cognition — Posted on 2020-01-11

2576 MATERNAL ZIKA VIRUS (ZIKV) INFECTION FOLLOWING VAGINAL INOCULATION WITH ZIKV-INFECTED SEMEN IN THE TIMED-PREGNANT OLIVE BABOON

Gurung, S.; Nadeau, H.; Maxted, M.; Peregrine, J.; Reuter, D. N.; Norris, A.; Edwards, R. K.; Hyatt, K.; Singleton, K.; Papin, J. F.; Myers, D. A.

10.1101/2020.01.10.902692 — physiology — Posted on 2020-01-11

2577 Open syntaxin overcomes synaptic transmission defects in diverse C. elegans exocytosis mutants

Tien, C.-W.; Yu, B.; Huang, M.; Stepin, K.; Sugita, K.; Xie, X.; Han, L.; Monnier, P.; Zhen, M.; Rizo, J.; Gao, S.; Sugita, S.

10.1101/2020.01.10.901835 — neuroscience — Posted on 2020-01-11

2578 NRF1 and NRF3 complementarily maintain a basal proteasome activity in cancer cells through CPEB3-mediated translational repression

Waku, T.; Katayama, H.; Hiraoka, M.; Hatanaka, A.; Nakamura, N.; Tanaka, Y.; Tamura, N.; Watanabe, A.; Kobayashi, A.

10.1101/2020.01.10.902718 — molecular biology — Posted on 2020-01-11

2579 ChiS is a noncanonical DNA-binding hybrid sensor kinase that directly regulates the chitin utilization program in Vibrio cholerae

Klancher, C. A.; Yamamoto, S.; Dalia, T. N.; Dalia, A. B.

10.1101/2020.01.10.902320 — microbiology — Posted on 2020-01-11

2580 Genomic rearrangements generate hypervariable mini-chromosomes in host-specific lineages of the blast fungus

Langner, T.; Harant, A.; Gomez-Luciano, L. B.; Shrestha, R. K.; Win, J.; Kamoun, S.

10.1101/2020.01.10.901983 — genomics — Posted on 2020-01-11

2581 Highly Multiplexed Single-Cell Full-Length cDNA Sequencing of human immune cells with 10X Genomics and R2C2

Volden, R.; Vollmers, C.

10.1101/2020.01.10.902361 — genomics — Posted on 2020-01-11

2582 Population sequencing data reveal a compendium of mutational processes in human germline

Seplyarskiy, V. B.; Soldatov, R.; McGinty, R. J.; Goldmann, J. M.; Hernandez, R.; Barnes, K.; Correa, A.; Burchard, E.; Ellinor, P.; McGarvey, S.; Mitchell, B.; Ramachandran, V.; Redline, S.; Silverman, E.; Weiss, S.; Arnett, D.; Blangero, J.; Boerwinkle, E.; He, J.; Montgomery, C.; Rao, D. C.; Rotter, J.; Brody, J.; Chen, Y.-D. I.; Fuentes, L.; Hwu, C.-M.; Rich, S.; Manichaikul, A.; Mychaleckyj, J.; Palmer, N.; Smith, J.; Kardia, S.; Peyser, P.; Bielak, L.; O'Connor, T.; Emery, L.; NHLBI Trans-Omics for Precision Medicine (TOPMed), ; TOPMed Population Genetics Working Group, ; Gilissen, C.;

10.1101/2020.01.10.893024 — genetics — Posted on 2020-01-11

2583 Perfect mimicry between Heliconius butterflies is constrained by genetics and development

Van Belleghem, S. M.; Alicea Roman, P. A.; Carbia Gutierrez, H.; Counterman, B. A.; Papa, R.

10.1101/2020.01.10.902494 — evolutionary biology — Posted on 2020-01-11

2584 Imidacloprid Movement into Fungal Conidia is Lethal to Mycophagous Beetles

Choudhury, R. A.; Sutherland, A. M.; Hengel, M. J.; Parrella, M. P.; Gubler, W. D.

10.1101/2020.01.11.901751 — ecology — Posted on 2020-01-11

2585 Rapid and accurate SNP genotyping of clonal bacterial pathogens with BioHansel

Labbe, G.; Kruczkiewicz, P.; Mabon, P.; Robertson, J.; Schonfeld, J.; Kein, D.; Rankin, M. A.; Gopez, M.; Hole, D.; Son, D.; Knox, N.; Laing, C. R.; Bessonov, K.; Taboada, E. N.; Yoshida, C.; Ziebell, K.; Nichani, A.; Johnson, R. P.; Van Domselaar, G.; Nash, J. H. E.

10.1101/2020.01.10.902056 — bioinformatics — Posted on 2020-01-11

2586 PhyteByte: Identification of foods containing compounds with specific pharmacological properties

Westerman, K.; Harrington, S.; Ordovas, J. M.; Parnell, L. D.

10.1101/2020.01.10.902197 — bioinformatics — Posted on 2020-01-11

2587 Tyrosine-Derived Polycarbonate Nerve Guidance Tubes Elicit Pro-Regenerative Extracellular Matrix Deposition When Used to Bridge Segmental Nerve Defects in Swine

Burrell, J. C.; Bhatnagar, D.; Brown, D. P.; Murthy, N. S.; Dutton, J.; Laimo, F. A.; Ali, Z.; Rosen, J. M.; Kaplan, H. M.; Kohn, J.; Cullen, D. K.

10.1101/2020.01.11.902007 — bioengineering — Posted on 2020-01-11

2588 An amygdalo-parabrachial pathway regulates pain perception and chronic pain

Raver, C.; Uddin, O.; Ji, Y.; Li, Y.; Cramer, N.; Jenne, C.; Morales, M.; Masri, R.; Keller, A.

10.1101/2020.01.10.902205 — neuroscience — Posted on 2020-01-11

2589 The rifampicin-inactivating mono-ADP-ribosyl transferase of Mycobacterium smegmatis significantly influences reactive oxygen species levels in the actively growing cells

Swaminath, S.; Pradhan, A.; Nair, R. R.; Ajitkumar, P.

10.1101/2020.01.10.902668 — microbiology — Posted on 2020-01-11

2590 The dynamic surface proteomes of allergenic fungal conidia

Blango, M. G.; Pschibul, A.; Rivieccio, F.; Krueger, T.; Rafiq, M.; Jia, L.-J.; Zheng, T.; Goldmann, M.; Voltersen, V.; Li, J.; Panagiotou, G.; Kniemeyer, O.; Brakhage, A. A.

10.1101/2020.01.10.902015 — microbiology — Posted on 2020-01-11

2591 Chaperone mediated coupling of subunit availability to activation of proton motive force-driven flagellar Type III Secretion

Bryant, O. J.; Chung, B. Y.-W.; Fraser, G. M.

10.1101/2020.01.10.902387 — microbiology — Posted on 2020-01-11

2592 Topologically associating domain (TAD) boundaries stable across diverse cell types are evolutionarily constrained and enriched for heritability

McArthur, E.; Capra, J. A.

10.1101/2020.01.10.901967 — genomics — Posted on 2020-01-11

2593 Comparing Phylogeographies: Incompatible Geographical Histories in Pathogens' Genomes

Singer, B. J.; Di Nardo, A.; Hein, J. J.; Ferretti, L.

10.1101/2020.01.10.902460 — genomics — Posted on 2020-01-11

2594 Rare protein coding variants implicate genes involved in risk of suicide death

DiBlasi, E.; Shabalin, A. A.; Monson, E. T.; Keeshin, B. R.; Bakian, A. V.; Kirby, A. V.; Ferris, E.; Chen, D.; William, N.; Gaj, E.; Klein, M.; Jerominski, L.; Callor, W. B.; Christensen, E.; Gray, D.; Smith, K. R.; Fraser, A.; Yu, Z.; PsychChip Investigators of the Psychiatric Genomics Consortium, ; Camp, N. J.; Stahl, E. A.; Li, Q. S.; Docherty, A. R.; Coon, H.

10.1101/2020.01.10.902304 — genetics — Posted on 2020-01-11

2595 Ultra-deep sequencing differentiates patterns of skin clonogenic mutations associated with sun-exposure status

Wei, L.; Fitzgerald, M.; Graham, J.; Hutson, N.; Zhang, C.; Huang, Z.; Hu, Q.; Zhan, F.; Xie, J.; Zhang, J.; Liu, S.; Remenyik, E.; Gellen, E.; Colegio, O. R.; Christensen, S.; Lin, H.; Bax, M.; Xu, J.; Huss, W. J.; Foster, B. A.; Paragh, G.

10.1101/2020.01.10.902098 — cancer biology — Posted on 2020-01-11

2596 The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer

10.1101/2020.01.10.902528 — cancer biology — Posted on 2020-01-11

2597 Using Natural Language Processing to Learn the Grammar of Glycans

Bojar, D.; Camacho, D. M.; Collins, J. J.

10.1101/2020.01.10.902114 — bioinformatics — Posted on 2020-01-11

2598 Efficient and accurate inference of microbial trajectories from longitudinal count data

Joseph, T. A.; Pasarkar, A. P.; Pe'er, I.

10.1101/2020.01.10.902163 — bioinformatics — Posted on 2020-01-11

2599 Maternally derived sex steroid hormones impact sex ratios of loggerhead sea turtles

Lockley, E. C.; Reschig, T.; Eizaguirre, C.

10.1101/2020.01.10.901520 — physiology — Posted on 2020-01-11

2600 Intestine-specific deletion of metal transporter Zip14 (Slc39a14) causes brain manganese overload and locomotor defects of manganism

Aydemir, T. B.; Thorn, T. L.; Ruggiero, C. H.; Pompilus, M.; Febo, M.; Cousins, R. J.

10.1101/2020.01.10.902122 — neuroscience — Posted on 2020-01-11

2601 Advantages and limits of metagenomic assembly and binning of a giant virus

Schulz, F.; Adreani, J.; Francis, R.; Bou Khalil, J. Y.; Lee, J.; LA SCOLA, B.; Woyke, T.

10.1101/2020.01.10.902254 — microbiology — Posted on 2020-01-11

2602 Antigen responsive CD4+ T cell clones contribute to the HIV-1 latent reservoir

Mendoza, P.; Jackson, J. R.; Oliveira, T.; Gaebler, C.; Ramos, V.; Caskey, M.; Jankovic, M.; Nussenzweig, M. C.; Cohn, L. B.

10.1101/2020.01.10.902155 — immunology — Posted on 2020-01-11

2603 A novel phylogenetic analysis combined with a machine learning approach predicts human mitochondrial variant pathogenicity

Akpinar, B. A.; Carlson, P. O.; Dunn, C. D.

10.1101/2020.01.10.902239 — evolutionary biology — Posted on 2020-01-11

2604 Chemical-Genetic Interrogation of Nuclear Size Control Reveals Cancer-Specific Effects on Cell Migration and Invasion

Rizzotto, A.; Tollis, S.; Pham, N. T.; Wildenhain, J.; Zuleger, N.; Keys, J. T.; Batrakou, D.; Culley, J.; Zheng, S.; Lammerding, J.; Carragher, N. O.; Brunton, V.; Auer, M.; Tyers, M.; Schirmer, E. C.

10.1101/2020.01.10.902148 — cancer biology — Posted on 2020-01-11

2605 Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide

Michaels, T. C.; Saric, A.; Curk, S.; Bernfur, K.; Arosio, P.; Meisl, G.; Dear, A.; Cohen, S.; Vendruscolo, M.; Dobson, C. M.; Linse, S.; Knowles, T. P.

10.1101/2020.01.08.897488 — biophysics — Posted on 2020-01-11

2606 Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling

Johnson, J. R.; Crosby, D. C.; Hultquist, J. F.; Li, D.; Marlett, J.; Swann, J.; Hüttenhain, R.; Verschueren, E.; Johnson, T. L.; Newton, B. W.; Shales, M.; Beltrao, P.; Frankel, A. D.; Marson, A.; Fregoso, O. I.; Young, J. A.; Krogan, N. J.

10.1101/2020.01.06.896365 — microbiology — Posted on 2020-01-11

2607 Scalable generation of mesenchymal stem cells and adipocytes from human pluripotent stem cells

Karam, M.; Younis, I.; Abdelalim, E. M.

10.1101/2020.01.11.902833 — developmental biology — Posted on 2020-01-11

2608 The extent and drivers of gender imbalance in neuroscience reference lists

Dworkin, J. D.; Linn, K. A.; Teich, E. G.; Zurn, P.; Shinohara, R. T.; Bassett, D. S.

10.1101/2020.01.03.894378 — scientific communication and education — Posted on 2020-01-11

2609 Adipokines set neural tone by regulating synapse number

Brent, A. E.; Rajan, A.

10.1101/781526 — physiology — Posted on 2020-01-11

2610 CRL5-dependent regulation of Arl4c and Arf6 controls hippocampal morphogenesis.

Han, J. S.; Hino, K.; Reyes, R. V.; Canales, C. P.; Miltner, A. M.; Haddadi, Y.; Sun, J.; Chen, C.-Y.; La Torre, A.; Simo, S.

10.1101/2020.01.10.902221 — developmental biology — Posted on 2020-01-11

2611 Spatially compartmentalized phase regulation of a Ca2+-cAMP-PKA oscillatory circuit

Tenner, B.; Getz, M.; Ross, B.; Ohadi, D.; Bohrer, C. H.; Greenwald, E.; Mehta, S.; Xiao, J.; Rangamani, P.; Zhang, J.

10.1101/2020.01.10.902312 — cell biology — Posted on 2020-01-11

2612 Macromolecular and biochemical changes of G0 fission yeast nuclei

Cai, S.; Tan, Z. Y.; Nie, X.; Shi, J.; Gan, L.

10.1101/2020.01.11.899559 — cell biology — Posted on 2020-01-11

2613 Size regulation of multiple organelles competing for a shared subunit pool

Banerjee, D. S.; Banerjee, S.

10.1101/2020.01.11.902783 — biophysics — Posted on 2020-01-11

2614 Electrophysiological Frequency Band Ratio Measures Conflate Periodic and Aperiodic Neural Activity

Donoghue, T.; Dominguez, J.; Voytek, B.

10.1101/2020.01.11.900977 — neuroscience — Posted on 2020-01-11

2615 Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation

Halstead, M. M.; Ma, X.; Schultz, R. M.; Ross, P. J.

10.1101/2019.12.12.874479 — developmental biology — Posted on 2020-01-11

2616 Decoding differential gene expression

Tasaki, S.; Gaiteri, C.; Mostafavi, S.; Wang, Y.

10.1101/2020.01.10.894238 — systems biology — Posted on 2020-01-11

2617 Origin of co-operativity in the activation of dimeric transcription factors

Welch, M.; Brasen, J. C.; Workman, C. T.; Sams, T.

10.1101/769661 — molecular biology — Posted on 2020-01-11

2618 Chromatin accessibility and histone acetylation in the regulation of competence in early development

Esmaeili, M.; Blythe, S. A.; Tobias, J. W.; Zhang, K.; Yang, J.; Klein, P. S.

10.1101/797183 — developmental biology — Posted on 2020-01-11

2619 Modulation of the canonical Wnt activity by androgen signaling in prostate epithelial basal stem cells

Liu, Y.; Wang, J.; Horton, C.; Katzman, S.; Cai, T.; Wang, Z. A.

10.1101/2020.01.10.902270 — developmental biology — Posted on 2020-01-11

2620 BAF facilitates interphase nuclear envelope repair through recruitment of nuclear transmembrane proteins.

Young, A. M.; Gunn, A. L.; Hatch, E. M.

10.1101/2020.01.10.902296 — cell biology — Posted on 2020-01-11

2621 Population Structure, Stratification and Introgression of Human Structural Variation.

Almarri, M. A.; Bergstrom, A.; Prado-Martinez, J.; Yang, F.; Fu, B.; Dunham, A. S.; Chen, Y.; Hurles, M.; Tyler-Smith, C.; Xue, Y.

10.1101/746172 — genomics — Posted on 2020-01-11

2622 The Architecture of GluD2 Ionotropic Delta Glutamate Receptor Elucidated by cryo-EM

Burada, A. P.; Kumar, J.

10.1101/2020.01.10.902072 — biochemistry — Posted on 2020-01-11

2623 Gene-Set Enrichment with Mathematical Biology

Cochran, A.; Nieser, K.; Forger, D.; Zöllner, S.; McInnis, M.

10.1101/554212 — genetics — Posted on 2020-01-11

2624 Generation of Monophasic Action Potentials and Intermediate Forms

Iravanian, S.; Uzelac, I.; Herndon, C. J.; Langberg, J.; Fenton, F.

10.1101/2020.01.10.901793 — biophysics — Posted on 2020-01-11

2625 The synthetically produced predator odor 2,5-dihydro-2,4,5-trimethylthiazoline increases alcohol self-administration and alters basolateral amygdala response to alcohol in rats.

Makhijani, V. H.; Franklin, J. P.; Van Voorhies, K.; Fortino, B.; Besheer, J.

10.1101/2020.01.10.901736 — neuroscience — Posted on 2020-01-11

2626 TALC: Transcription-Aware Long Read Correction

Broseus, L.; Thomas, A.; Oldfield, A.; Sevrac, D.; Dubois, E.; Ritchie, W. J.

10.1101/2020.01.10.901728 — bioinformatics — Posted on 2020-01-11

2627 Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development

Morandell, J.; Schwarz, L. A.; Basilico, B.; Tasciyan, S.; Nicolas, A.; Sommer, C.; Kreuzinger, C.; Dotter, C. P.; Knaus, L. S.; Dobler, Z.; Cacci, E.; Danzl, J. G.; Novarino, G.

10.1101/2020.01.10.902064 — neuroscience — Posted on 2020-01-11

2628 Genome-wide transcriptomics identifies an early preclinical signature of prion infection

Sorce, S.; Nuvolone, M.; Russo, G.; Chincisan, A.; Heinzer, D.; Avar, M.; Pfammatter, M.; Schwarz, P.; Delic, M.; Hornemann, S.; Sanoudou, D.; Scheckel, C.; Aguzzi, A.

10.1101/2020.01.10.901637 — neuroscience — Posted on 2020-01-11

2629 The RNA pseudoknots in foot-and-mouth disease virus are dispensable for genome replication but essential for the production of infectious virus.

Ward, J. C. J.; Lasecka-Dykes, L.; Neil, C.; Adeyemi, O.; Gold, S.; McLean, N.; Wright, C.; Herod, M. R.; Kealy, D.; Warner, E.; King, D. P.; Tuthill, T. J.; Rowlands, D. J.; Stonehouse, N. J.

10.1101/2020.01.10.901801 — molecular biology — Posted on 2020-01-11

2630 The formation and function of focus-like structures of Hfq in long-term nitrogen starved Escherichia coli

McQuail, J.; Switzer, A.; Burchell, L.; Wigneshweraraj, R.

10.1101/2020.01.10.901611 — microbiology — Posted on 2020-01-11

2631 A Physiological Characterization in Controlled Bioreactors Reveals a Novel Survival Strategy for Debaryomyces hansenii at High Salinity and Confirms its Halophilic Behavior

Navarrete, C.; Frost, A. T.; Ramos-Moreno, L.; Martinez, J. L.

10.1101/2020.01.10.901843 — microbiology — Posted on 2020-01-11

2632 Identification of Photorhabdus symbionts by MALDI-TOF mass spectrometry

Hill, V.; Kuhnert, P.; Erb, M.; Machado, R. A. R.

10.1101/2020.01.10.901900 — microbiology — Posted on 2020-01-11

2633 Expansion of Functional Regulatory T Cells Using Soluble RAGE Prevents Type 1 Diabetes

Leung, S.; Borg, D. J.; McCarthy, D. A.; Boursalian, T.; Cracraft, J.; Zhuang, A.; Fotheringham, A.; Flemming, N.; Watkins, T.; Miles, J.; Groop, P.-H.; Scheijen, J.; Schalkwijk, C.; Steptoe, R.; Radford, K.; Knip, M.; Forbes, J. M.

10.1101/2020.01.10.902627 — immunology — Posted on 2020-01-11

2634 A Learning-Based Formulation of Parametric Curve Fitting for Bioimage Analysis

Mandal, S.; Uhlmann, V.

10.1101/2020.01.10.901702 — bioinformatics — Posted on 2020-01-11

2635 Designing Novel Subunit Vaccines against Herpes Simplex Virus-1 using Reverse Vaccinology Approach

Sarkar, B.; Ullah, M. A.

10.1101/2020.01.10.901678 — bioinformatics — Posted on 2020-01-11

2636 ideal: an R/Bioconductor package for Interactive Differential Expression Analysis

Marini, F.; Linke, J.; Binder, H.

10.1101/2020.01.10.901652 — bioinformatics — Posted on 2020-01-11

2637 A census of cell types and paracrine interactions in colorectal cancer

Uhlitz, F.; Bischoff, P.; Sieber, A.; Obermayer, B.; Blanc, E.; Luethen, M.; Sawitzki, B.; Kamphues, C.; Beule, D.; Sers, C.; Horst, D.; Bluthgen, N.; Morkel, M.

10.1101/2020.01.10.901579 — cancer biology — Posted on 2020-01-11

2638 Concepts and Software Package for Efficient Quality Control in Targeted Metabolomics Studies - MeTaQuaC

Kuhring, M.; Eisenberger, A.; Schmidt, V.; Kraenkel, N.; Leistner, D. M.; Kirwan, J.; Beule, D.

10.1101/2020.01.10.901710 — bioinformatics — Posted on 2020-01-11

2639 Development of Systemic Immune Dysregulation in a Rat Trauma Model with Biomaterial-Associated Infection

Vantucci, C. E.; Ahn, H.; Schenker, M. L.; Pradhan, P.; Wood, L. B.; Guldberg, R. E.; Roy, K.; Willett, N.

10.1101/2020.01.10.901769 — bioengineering — Posted on 2020-01-11

2640 One-to-one innervation of vocal muscles allows precise control of birdsong

Adam, I.; Maxwell, A.; Rössler, H.; Hansen, E. B.; Vellema, M.; Elemans, C. P.

10.1101/2020.01.10.901561 — neuroscience — Posted on 2020-01-11

2641 Stromal Amyloid β drives Neutrophil extracellular trap formation to augment tumour growth

Munir, H.; Jones, J. O.; Janowitz, T.; Martins, C. P.; Welsh, S. P.; Shields, J. D.

10.1101/2020.01.10.901686 — cancer biology — Posted on 2020-01-11

2642 Crosslinking-guided geometry of a complete CXC receptor-chemokine complex and the basis of chemokine subfamily selectivity

Ngo, T.; Stephens, B. S.; Gustavsson, M.; Holden, L. G.; Abagyan, R.; Handel, T. M.; Kufareva, I.

10.1101/2020.01.10.900951 — biochemistry — Posted on 2020-01-11

2643 Characterization of novel Actinobacteriophage Giantsbane reveals potential genomic recombination hotspot and unexpected intra-cluster similarities

Liu, C.; Chen, P. Y.; Dang, P.; Zhang, M.; Kapinos, A.; Ngo, R. T.; Moberg Parker, J.; Freise, A. C.

10.1101/2020.01.10.891226 — genomics — Posted on 2020-01-11

2644 Geometric Analysis of Regime Shifts in Coral Reef Communities

Tekwa, E. W.; McManus, L. C.; Greiner, A.; Colton, M. A.; Webster, M. S.; Pinsky, M. L.

10.1101/2020.01.10.899179 — ecology — Posted on 2020-01-11

2645 RNA splicing alterations induce a cellular stress response associated with poor prognosis in AML

Anande, G.; Deshpande, N. P.; Mareschal, S.; Batcha, A. M. N.; Hampton, H. R.; Herold, T.; Lehmann, S.; Wilkins, M. R.; Wong, J. W. H.; Unnikrishnan, A.; Pimanda, J. E.

10.1101/2020.01.10.895714 — cancer biology — Posted on 2020-01-11

2646 Talin Folding; the Tuning Fork of Cellular Mechanotransduction

Tapia-Rojo, R.; Fernandez, J. M.

10.1101/2020.01.10.901991 — biophysics — Posted on 2020-01-11

2647 Melanopsin Carboxy-terminus Phosphorylation Plasticity and Bulk Negative Charge, not Strict Site Specificity, Achieves Phototransduction Deactivation

Valdez-Lobez, J. C.; Gulati, S.; Ortiz, E. A.; Palczewski, K.; Robinson, P.

10.1101/2020.01.09.900050 — neuroscience — Posted on 2020-01-11

2648 Effect of extracorporeal shock wave therapy on equine umbilical cord blood mesenchymal stromal cells in vitro

Salcedo-Jimenez, R.; Koenig, J.; Lee, O.; Gibson, T. W. G.; Madan, P.; Koch, T. G.

10.1101/2020.01.10.901439 — cell biology — Posted on 2020-01-11

2649 Real-time measurement of E2:ERα transcriptional activity in living cells.

Cipolletti, M.; Leone, S.; Bartoloni, S.; Busonero, C.; Acconcia, F.

10.1101/844761 — physiology — Posted on 2020-01-11

2650 PPM-Decay: A Computational Model of Auditory Prediction with Memory Decay

Harrison, P. M. C.; Bianco, R.; Chait, M.; Pearce, M. T.

10.1101/2020.01.09.900266 — animal behavior and cognition — Posted on 2020-01-11

2651 Virulence phenotypes result from an interaction between pathogen ploidy and genetic background

Feistel, D. J.; Elmostafa, R. B.; Hickman, M. A.

10.1101/672519 — genetics — Posted on 2020-01-11

2652 Multiple resource use strategies confer resilience to the socio-ecosystem in a protected area in the Yucatan Peninsula, Mexico

Garcia Jacome, L. G.; Garcia-Frapolli, E.; Bonilla-Moheno, M.; Rangel Rivera, C.; Benitez, M.; Ramos-Fernandez, G.

10.1101/2020.01.08.897462 — ecology — Posted on 2020-01-11

2653 Ecotone formation through ecological niche construction: the role of biodiversity and species interactions

Liautaud, K.; Barbier, M.; Loreau, M.

10.1101/740282 — ecology — Posted on 2020-01-11

2654 TarDict: RandomForestClassifier-based software predict Drug-Tartget interaction in human Based on drug simplified molecular-input line-entry system (SMILES)

Habib, P.; Alsamman, A. M.; Hassanein, S.; Hamwieh, A.

10.1101/2020.01.08.899005 — bioinformatics — Posted on 2020-01-11

2655 Decoding differential gene expression

Tasaki, S.; Gaiteri, C.; Mostafavi, S.; Wang, Y.

10.1101/2020.01.10.894238 — systems biology — Posted on 2020-01-11

2656 Assessment of anesthesia on physiological stability and BOLD signal reliability during visual or acoustic stimulation in the cat

Levine, A. T.; Li, B.; Barnes, P.; Lomber, S. G.; Butler, B. E.

10.1101/827949 — neuroscience — Posted on 2020-01-11

2657 Enabling high-accuracy long-read amplicon sequences using unique molecular identifiers with Nanopore or PacBio sequencing

Karst, S. M.; Ziels, R.; Kirkegaard, R. H.; Sorensen, E. A.; McDonald, D.; Zhu, Q.; Knight, R.; Albertsen, M.

10.1101/645903 — molecular biology — Posted on 2020-01-11

2658 Read coverage as an indicator of misassembly in a short-read based genome assembly

Wang, P.; Meng, F.; Moore, B. M.; Shiu, S.-H.

10.1101/790337 — genomics — Posted on 2020-01-11

2659 Novel IRE1-dependent proinflammatory signaling controls tumor infiltration by myeloid cells.

Obacz, J.; Archambeau, J.; Le Reste, P. J.; Pineau, R.; Barroso, K.; Vlachavas, E.; Voutetakis, K.; Fainsod-Levi, T.; Obiedat, A.; Granot, Z.; Tirosh, B.; Samal, J.; Pandit, A.; Patterson, J.; Zheng, Q.; Negroni, L.; Chatziioannou, A.; Quillien, V.; Avril, T.; chevet, e.

10.1101/533018 — cancer biology — Posted on 2020-01-11

2660 Cell segmentation using deep learning: comparing label and label-free approaches using hyper-labeled image stacks

Cameron, W. D.; Bui, C. V.; Bennett, A. M.; Chang, H. H.; Rocheleau, J. V.

10.1101/2020.01.09.900605 — bioengineering — Posted on 2020-01-11

2661 Endogenous polybasic polypeptides cause slower movement of ribosomes but are not targets of the ribosome quality control (RQC) complex

Barros, G. C.; Requiao, R. D.; Carneiro, R. L.; Masuda, C. A.; Moreira, M. H.; Rossetto, S.; Domitrovic, T.; Palhano, F.

10.1101/849851 — biochemistry — Posted on 2020-01-11

2662 A young age of subspecific divergence in the desert locust Schistocerca gregaria inferred by ABC Random Forest

Chapuis, M.-P.; Raynal, L.; Plantamp, C.; Meynard, C. N.; Blondin, L.; Marin, J.-M.; Estoup, A.

10.1101/671867 — evolutionary biology — Posted on 2020-01-11

2663 Multiple merger genealogies in outbreaks of Mycobacterium tuberculosis

Menardo, F.; Gagneux, S.; Freund, F.

10.1101/2019.12.21.885723 — evolutionary biology — Posted on 2020-01-11

2664 Red Panda: A novel method for detecting variants in single-cell RNA sequencing

Cornish, A.; Roychoudhury, S.; Sarma, K.; Pramanik, S.; Bhakat, K.; Mishra, N. K.; Guda, C.

10.1101/2020.01.08.898874 — bioinformatics — Posted on 2020-01-11

2665 CASC3 promotes transcriptome-wide activation of nonsense-mediated decay by the exon junction complex

Gerbracht, J. V.; Boehm, V.; Britto-Borges, T.; Kallabis, S.; Wiederstein, J. L.; Ciriello, S.; Aschemeier, D. U.; Krueger, M.; Frese, C. K.; Altmueller, J.; Dieterich, C.; Gehring, N. H.

10.1101/811018 — molecular biology — Posted on 2020-01-11

2666 NFATC4 Promotes Quiescence and Chemotherapy Resistance in Ovarian Cancer

Cole, A. J.; Iyengar, M.; OHayer, P.; Chan, D.; Greg Delgoffe, G.; Aird, K. M.; Yoon, E.; Bai, S.; Buckanovich, R. J.

10.1101/825497 — cancer biology — Posted on 2020-01-11

2667 Breaking a Strong Amide Bond: Structure and Properties of Dimethylformamidase.

Arya, C. K.; Yadav, S.; Fine, J.; Casanal, A.; Chopra, G.; Ramanathan, G.; Vinothkumar, K. R.; Subramanian, R.

10.1101/2019.12.17.879908 — biochemistry — Posted on 2020-01-11

2668 Standard multiscale entropy reflects spectral power at mismatched temporal scales: What's signal irregularity got to do with it?

Kosciessa, J. Q.; Kloosterman, N. A.; Garrett, D. D.

10.1101/752808 — neuroscience — Posted on 2020-01-11

2669 Intraspecific difference among herbivore lineages and their host-plant specialization drive the strength of trophic cascades

Sentis, A.; Bertram, R.; Dardenne, N.; Simon, J.-C.; Magro, A.; Pujol, B.; Danchin, E.; Hemptinne, J.-L.

10.1101/722140 — ecology — Posted on 2020-01-11

2670 Tiled Reconstruction Improves Structured Illumination Microscopy

Hoffman, D. P.; Betzig, E.

10.1101/2020.01.06.895318 — cell biology — Posted on 2020-01-11

2671 Mining the Selective Remodeling of DNA Methylation in Promoter Regions to Identify Robust Gene-Level Associations with Phenotype

Yuan, Q.; Liang, F.; Zhu, Y.; Chen, Y.; Xu, R.; Xiong, J.

10.1101/2020.01.05.895326 — bioinformatics — Posted on 2020-01-11

2672 Amplitude effects allow short jetlags and large seasonal phase shifts in minimal clock models

Ananthasubramaniam, B.; Schmal, C.; Herzel, H.

10.1101/825331 — systems biology — Posted on 2020-01-11

2673 High-content assay for CFTR monitoring: simultaneous quantification of channel function and biogenesis.

Prins, S.; Langron, E.; Hastings, C.; Hill, E. J.; Stefan, A. C.; Griffin, L. D.; Vergani, P.

10.1101/631614 — pharmacology and toxicology — Posted on 2020-01-11

2674 Acute Stress Reduces Reward-Related Neural Activity: Evidence from the Reward Positivity

Burani, K.; Gallyer, A. J.; Ryan, J.; Jordan, C.; Joiner, T. E.; Hajcak, G.

10.1101/2020.01.08.898593 — neuroscience — Posted on 2020-01-11

2675 Behavioral evidence for memory replay of video episodes in macaque monkeys

Zuo, S.; Wang, L.; Shin, J.; Cai, Y.; Lee, S. W.; Appiah, K.; Zhou, Y.-d.; Kwok, S. C.

10.1101/2020.01.10.902130 — neuroscience — Posted on 2020-01-11

2676 Temporal interference stimulation targets deep brain regions by modulating neural oscillations

Esmaeilpour, Z.; Kronberg, G.; Reato, D.; Parra, L. C.; Bikson, M.

10.1101/2019.12.25.888412 — neuroscience — Posted on 2020-01-11

Azzalini, D.; Buot, A.; Palminteri, S.; Tallon-Baudry, C.

10.1101/776047 — neuroscience — Posted on 2020-01-11

2678 AlphaBeta: Computational inference of epimutation rates and spectra from high-throughput DNA methylation data in plants

Shahryary Dizaji, Y.; Symeonidi, A.; Hazarika, R. R.; Denkena, J.; Mubeen, T.; Hofmeister, B.; van Gurp, T.; Colome-Tatche, M.; Verhoeven, K.; Tuskan, G.; Schmitz, R. J.; Johannes, F.

10.1101/862243 — genomics — Posted on 2020-01-11

2679 Stoichiometric constraints modulate the effects of temperature and nutrients on biomass distribution and community stability

Sentis, A.; Haegeman, B.; Montoya, J. M.

10.1101/589895 — ecology — Posted on 2020-01-11

2680 Light scatter and fluorescence calibration allow standard comparisons of small particle data between different instruments.

Welsh, J. A.; Tang, V. A.

10.1101/796961 — cell biology — Posted on 2020-01-11

2681 Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions

Lord, C. J.; Quinn, N.; Ryan, C. J.

10.1101/646810 — cancer biology — Posted on 2020-01-11

2682 Mitigating Local Over-fitting During Single Particle Reconstruction with SIDESPLITTER

Ramlaul, K.; Palmer, C. M.; Aylett, C. H. S.

10.1101/2019.12.12.874081 — biophysics — Posted on 2020-01-11

2683 Geographic assessment of cancer genome profiling studies

Carrio Cordo, P.; Acheson, E.; Huang, Q.; Baudis, M.

10.1101/827683 — bioinformatics — Posted on 2020-01-11

2684 Oct4 mediated inhibition of Lsd1 activity promotes the active and primed state of pluripotency enhancers

AlAbdi, L.; Saha, D.; He, M.; Dar, M. S.; Utturkar, S. M.; Sudyanti, P. A.; McCune, S.; Spears, B. H.; Breedlove, J. A.; Lanman, N. A.; Gowher, H.

10.1101/672451 — developmental biology — Posted on 2020-01-11

2685 Impaired EAT-4 Vesicular Glutamate Transporter Leads to Defective Nocifensive Response of Caenorhabditis elegans to Noxious Heat

Leonelli, S.; Nkambeu, B.; Beaudry, F.

10.1101/620302 — neuroscience — Posted on 2020-01-11

2686 Loss of Sarm1 non-autonomously protects Schwann cells from chemotoxicity

Lopez-Schier, H.; Tian, W.; Czopka, T.

10.1101/493163 — cell biology — Posted on 2020-01-11

2687 The relationship between the waiting time of postoperative radiotherapy and the prognosis of high grade glioma:a systemic review and meta-analysis.

Li, G.-l.; Lv, S.; Xu, Y.; Zhang, H.-b.; Yan, Y.

10.1101/2020.01.10.901447 — cancer biology — Posted on 2020-01-10

2688 Differential risk of incident cancer in patients with heart failure: A nationwide population-based cohort study

Kwak, S.; Kwon, S.; Lee, S.-Y.; Yang, S.; Lee, H.-J.; Lee, H.; Park, J.-B.; Han, K.; Kim, Y.-J.; Kim, H.-K.

10.1101/2020.01.10.901454 — cancer biology — Posted on 2020-01-10

2689 A new plant-specific syntaxin-6 protein may define an intracytoplasmic route for begomoviruses

Fontes, E. P. B.; Gouveia-Mageste, B. C.; Martins, L. G. C.; Dal-Bianco, M.; Machado, J. P. B.; Silva, J. C. F.; Santos, A. A.; Ecker, J. R.

10.1101/2020.01.10.901496 — plant biology — Posted on 2020-01-10

2690 Serological evidence of Rift Valley fever infection and risk factors among one humped camels (Camelus dromedarius) in Northern Nigeria.

Adamu, A. M.; Yila, S. A.; Allam, L.; Sackey, A.; Alhaji, N. B.; Garba, B. S.; Mambula, S. M.; Nafarnda, W. D.; Idoko, I. S.; Balogun, E. O.; Owolodun, O. A.; Dzikwi, A. A.

10.1101/2020.01.10.901470 — microbiology — Posted on 2020-01-10

2691 Various miRNAs are involved in efficient HCV replication

Ono, C.; Fukuhara, T.; Li, S.; Wang, J.; Sato, A.; Izumi, T.; Fauzyah, Y.; Yamamoto, T.; Morioka, Y.; Dokholyan, N. V.; Standley, D. M.; Matsuura, Y.

10.1101/2020.01.10.901488 — microbiology — Posted on 2020-01-10

2692 Offspring performance is well buffered against stress experienced by ancestors

Pei, Y.; Forstmeier, W.; Kempenaers, B.

10.1101/2020.01.10.901421 — evolutionary biology — Posted on 2020-01-10

2693 Endemic and epidemic human alphavirus infections in Eastern Panama, An Analysis of Population-Based Cross-Sectional Surveys

Carrera, J. P.; Cucunuba, Z. M.; Neira, K.; Lambert, B.; Pitti, Y.; Jackman, C.; Liscano, J.; Garzon, J.; Beltran, D.; Collado-Mariscal, L.; Saenz, L.; Sosa, N.; Rodriguez-Guzman, L. D.; Gonzalez, P.; Lescano, A. G.; Pereyra-Elias, R.; Valderrama, A.; Weaver, S. C.; Vittor, A. Y.; Armien, B.; Pascale, J. M.; Donnelly, C. A.

10.1101/2020.01.10.901462 — microbiology — Posted on 2020-01-10

2694 Ephrin-B2 paces neuronal production in the developing neocortex

Kischel, A.; Audouard, C.; Fawal, M.-A.; Davy, A.

10.1101/2020.01.10.901587 — developmental biology — Posted on 2020-01-10

2695 Dendritic integration in olfactory bulb granule cells: Thresholds for lateral inhibition and role of active conductances upon simultaneous activation.

Mueller, M.; Egger, V.

10.1101/2020.01.10.901397 — neuroscience — Posted on 2020-01-10

2696 Decoding differential gene expression

Tasaki, S.; Gaiteri, C.; Mostafavi, S.; Wang, Y.

10.1101/2020.01.10.894238 — systems biology — Posted on 2020-01-10

2697 Study of application times gibberellic acid and 2,4-Dichlorophenoxyacetic acid in the plant regeneration from wheat haploid embryos in chromosome elimination method

Modirrousta, H. H.; Khademian, R.; Bozorgipour, R.

10.1101/2020.01.10.902023 — plant biology — Posted on 2020-01-10

2698 Radius-Optimized Efficient Template Matching for Lesion Detection from Brain Images

Koley, S.; Dutta, P. K.; Aganj, I.

10.1101/2020.01.10.893099 — neuroscience — Posted on 2020-01-10

2699 The intersection between the representation of the stimuli and the choice by neural ensembles in the primary visual cortex of the macaque.

Koren, V.; Andrei, A. R.; Hu, M.; Dragoi, V.; Obermayer, K.

10.1101/2020.01.10.901504 — neuroscience — Posted on 2020-01-10

2700 The snowmelt niche differentiates three microbial life strategies that influence soil nitrogen availability during and after winter

Sorensen, P.; Beller, H.; Bill, M.; Bouskill, N.; Hubbard, S.; Karaoz, U.; Polussa, A.; Steltzer, H.; Wang, S.; Williams, K.; Wu, Y.; Brodie, E.

10.1101/2020.01.10.900621 — microbiology — Posted on 2020-01-10

2701 Impact of trait exaggeration on sex-biased gene expression and genome architecture in a water strider

Toubiana, W.; Armisen, D.; Dechaud, C.; Arbore, R.; Khila, A.

10.1101/2020.01.10.901322 — genomics — Posted on 2020-01-10

2702 Short-term exposure to high-water temperature causes a shift in the microbiome of the common aquarium sponge Lendenfeldia chondrodes

Vargas, S.; Leiva, L.; Wörheide, G.

10.1101/2020.01.10.901363 — ecology — Posted on 2020-01-10

2703 Integrated Omics Analyses Reveal Differential Gene Expression and Potential for Cooperation Between Denitrifying Polyphosphate and Glycogen Accumulating Organisms

Wang, Y.; Gao, H.; Wells, G.

10.1101/2020.01.10.901413 — bioengineering — Posted on 2020-01-10

2704 Plant-pollinator interaction linkage rules are altered by agricultural intensification

Morrison, B. M. L.; Brosi, B.; Dirzo, R.

10.1101/2020.01.10.900878 — ecology — Posted on 2020-01-10

2705 Deep Learning Identifies Cardiomyocyte Nuclei in Murine Tissue with High Precision

Ali, S. R.; Nguyen, D.; Wang, B.; Jiang, S.; Sadek, H.

10.1101/2020.01.10.900936 — cell biology — Posted on 2020-01-10

2706 Amphetamine Maintenance Therapy During Intermittent Cocaine Self-Administration in Rats: Reduction of Addiction-like Behavior is Associated with Attenuation of Psychomotor and Dopamine Sensitization

Allain, F.; Delignat-Lavaud, B.; Beaudoin, M.-P.; Jacquemet, V.; Robinson, T. E.; Trudeau, L.-E.; Samaha, A.-N.

10.1101/2020.01.10.900852 — neuroscience — Posted on 2020-01-10

2707 Improving Deconvolution Methods in Biology through Open Innovation Competitions: An Application to the Connectivity Map

Blasco, A.; Natoli, T.; Endres, M. G.; Sergeev, R. A.; Randazzo, S.; Paik, J. H.; Macaluso, N. M.; Narayan, R.; Lu, X.; Peck, D.; Lakhani, K. R.; Subramanian, A.

10.1101/2020.01.10.897363 — genomics — Posted on 2020-01-10

2708 Staying in the club: Exploring criteria governing metacommunity membership for obligate symbionts under host-symbiont feedback

Venkateswaran, V.; Borges, R. M.

10.1101/2020.01.10.901314 — ecology — Posted on 2020-01-10

2709 Population Analysis of Extracellular Vesicles in Microvolumes of Biofluids

Maia, J.; Batista, S.; Couto, N.; Gregorio, A. C.; Bodo, C.; Elzanowska, J.; Strano Moraes, M. C.; Costa-Silva, B.

10.1101/2020.01.10.895037 — cell biology — Posted on 2020-01-10

2710 Longitudinal whole-exome sequencing of cell-free DNA unravels the metastatic evolutionary dynamics of BRCA2 mutated breast cancer

Hastings, R. K.; Openshaw, M. R.; Vazquez, M.; Moreno, A. B.; Fernandez-Garcia, D.; Martinson, L. J.; Toghill, B.; Kulbicki, K. J.; Primrose, L.; Guttery, D.; Page, K.; Richards, C.; Thomas, A.; Tabernero, J.; Coombes, R. C.; Ahmed, S.; Toledo, R.; Shaw, J. A.

10.1101/2020.01.10.901330 — cancer biology — Posted on 2020-01-10

2711 Viral Sequence Identification in Metagenomes using Natural Language Processing Techniques

Abdelkareem, A. O.; Khalil, M. I.; Elbehery, A. H.; Abbas, H. M.

10.1101/2020.01.10.892158 — bioinformatics — Posted on 2020-01-10

2712 PIE-FLIM measurements of two different FRET-based biosensor activities in the same living cells

Day, R. N.; Reissaus, C. A.; Day, K. H.; Mirmira, R. G.; Dunn, K. W.; Pavalko, F.

10.1101/2020.01.10.902213 — cell biology — Posted on 2020-01-10

2713 Trypanosoma cruzi senses intracellular heme levels and regulates heme homeostasis by modulating TcHTE protein expression

Pagura, L.; Tevere, E.; Merli, M. L.; Cricco, J. A.

10.1101/2020.01.10.901934 — biochemistry — Posted on 2020-01-10

2714 Behavioral evidence for memory replay of video episodes in macaque monkeys

Kwok, S. C.; Zuo, S.; Wang, L.; Shin, J.; Cai, Y.; Lee, S. W.; Appiah, K.; Zhou, Y.-d.

10.1101/2020.01.10.902130 — neuroscience — Posted on 2020-01-10

2715 Inactive variants of death receptor p75NTR reduce Alzheimer's neuropathology by interfering with APP internalization

Ibanez, C. F.; Yi, C.; Goh, K. Y.; Sreedharan, S.; Wong, L.-W.; Tanaka, K.

10.1101/2020.01.10.901926 — neuroscience — Posted on 2020-01-10

2716 Global transcriptome analysis reveals circadian control of splicing events in Arabidopsis thaliana

Romanowski, A.; Schlaen, R. G.; Perez-Santangelo, S.; Mancini, E.; Yanovsky, M. J.

10.1101/845560 — plant biology — Posted on 2020-01-10

2717 Akt/Foxo pathway activation switches apoptosis to senescence in short telomere zebrafish

Ferreira, M. G.; El-Maï, M.; Marzullo, M.; de Castro, I. P.

10.1101/2020.01.10.901603 — cell biology — Posted on 2020-01-10

2718 Individual behavioral type captured by a Bayesian model comparison in cap making by sponge crab

Harada, K.; Kagaya, K.

10.1101/330787 — animal behavior and cognition — Posted on 2020-01-10

2719 Presynaptic PTPσ organizes neurotransmitter release machinery at excitatory synapses

Han, K. A.; Lee, H.-Y.; Lim, D.; Shin, J.; Yoon, T. H.; Lee, C.; Liu, X.; Rhee, J.-S.; Um, J. W.; Choi, S. Y.; Ko, J.

10.1101/2020.01.10.901546 — neuroscience — Posted on 2020-01-10

2720 Tissue Engineered Vascularized Patient-Specific Temporomandibular Joint Reconstruction in a Yucatan Pig Model

Abramowicz, S.; Hollister, S.; Crotts, S.; Goudy, S.

10.1101/2020.01.09.900746 — bioengineering — Posted on 2020-01-10

2721 Searching for replicable associations between cortical thickness and psychometric variables in healthy adults: empirical facts.

Kharabian, S.; Eickhoff, S. B.; Genon, S.

10.1101/2020.01.10.901181 — neuroscience — Posted on 2020-01-10

2722 Competitive interactions between motor and episodic memory systems during interleaved learning

Kim, S.

10.1101/2020.01.10.901207 — neuroscience — Posted on 2020-01-10

2723 Common and distinct brain activity associated with risky and ambiguous decision-making

Poudel, R.; Riedel, M. C.; Salo, T.; Flannery, J. S.; Hill-Bowen, L. D.; Eickhoff, S. B.; Laird, A. R.; Sutherland, M. T.

10.1101/2020.01.09.900969 — neuroscience — Posted on 2020-01-10

2724 Recently expanded clonal lineages of the rice blast fungus display distinct patterns of presence/absence of effector genes

Latorre, S. M.; Reyes-Avila, C. S.; Malmgren, A.; Win, J.; Kamoun, S.; Burbano, H. A.

10.1101/2020.01.09.900308 — evolutionary biology — Posted on 2020-01-10

2725 The wisdom of stalemates: consensus and clustering as filtering mechanisms for improving collective accuracy

Winklmayr, C.; Kao, A. B.; Bak-Coleman, J. B.; Romanczuk, P.

10.1101/2020.01.09.899054 — animal behavior and cognition — Posted on 2020-01-10

2726 Increased likelihood of heat-induced large wildfires in the Mediterranean Basin

Ruffault, J.; Curt, T.; Moron, V.; Trigo, R.; Mouillot, F.; Koutsias, N.; Pimont, F.; Martin-StPaul, N.; Barbero, R.; Dupuy, J.-L.; Russo, A.; Belhadj-Kheder, C.

10.1101/2020.01.09.896878 — ecology — Posted on 2020-01-10

2727 Ocean currents promote rare species diversity in protists

Villa Martin, P.; Bucek, A.; Bourguignon, T.; Pigolotti, S.

10.1101/2020.01.10.901165 — ecology — Posted on 2020-01-10

2728 Cooperative and non-cooperative behaviour in the exploitation of a common renewable resource with environmental stochasticity

Hackney, M.; James, A.; Plank, M. J.

10.1101/2020.01.09.901025 — ecology — Posted on 2020-01-10

2729 Modelling bioactivities of combinations of whole extracts of edibles with a simplified theoretical framework reveals the statistical role of molecular diversity and system complexity in their mode of action and their nearly certain safety

Mayer, P.

10.1101/2020.01.09.899823 — pharmacology and toxicology — Posted on 2020-01-10

2730 Design and demonstration in vitro of mouse-specific Transcranial Magnetic Stimulation coil

Khokhar, F. A.; Voss, L. J.; Steyn-Ross, D. A.; Wilson, M. T.

10.1101/2020.01.09.900993 — neuroscience — Posted on 2020-01-10

2731 Genetic ablation of SOD1G37R selectively from corticofugal projection neurons protects corticospinal neurons from degeneration without affecting ALS onset and progression

Scekic-Zahirovic, J.; Fischer, M.; Stuart-Lopez, G.; Burg, T.; Birling, M.-C.; Kessler, P.; Rouaux, C.

10.1101/2020.01.09.900944 — neuroscience — Posted on 2020-01-10

2732 Sequence learning in a single trial: a spiking neurons model based on hippocampal circuitry

Coppolino, S.; Migliore, M.

10.1101/2020.01.09.898064 — neuroscience — Posted on 2020-01-10

2733 Nanopore Sequencing at Mars, Europa and Microgravity Conditions

Carr, C. E.; Bryan, N. C.; Saboda, K. N.; Bhattaru, S. A.; Ruvkun, G.; Zuber, M. T.

10.1101/2020.01.09.899716 — genomics — Posted on 2020-01-10

2734 Designing flow regimes to support entire river ecosystems

Tonkin, J. D.; Olden, J. D.; Merritt, D. M.; Reynolds, L. V.; Rogosch, J. S.; Lytle, D. A.

10.1101/2020.01.09.901009 — ecology — Posted on 2020-01-10

2735 ARID2 deficiency promotes tumor progression and is associated with higher sensitivity to PARP inhibition in lung cancer

Moreno, T.; Gonzalez-Silva, L.; Monterde, B.; Betancor-Fernandez, I.; Revilla, C.; Agraz-Doblas, A.; Freire, J.; Isidro, P.; Quevedo, L.; Montes-Moreno, S.; Cereceda, L.; Astudillo, A.; Casar, B.; Crespo, P.; Morales Torres, C.; Scaffidi, P.; Gomez-Roman, J.; Salido, E.; Varela, I.

10.1101/2020.01.10.898726 — cancer biology — Posted on 2020-01-10

2736 Colocalization highlights genes in hypothalamic-pituitary-gonadal axis as potentially mediating polycystic ovary syndrome risk

Censin, J. C.; Bovijn, J.; Holmes, M. V.; Lindgren, C. M.

10.1101/2020.01.10.901116 — genetics — Posted on 2020-01-10

2737 Pleiotropy promotes male exaggerated weapon and its associated fighting behaviour in a water strider

Toubiana, W.; Armisen, D.; Decaras, A.; Khila, A.

10.1101/2020.01.09.898098 — evolutionary biology — Posted on 2020-01-10

2738 Nanoscale Structure Determination of Murray Valley Encephalitis and Powassan Virus Non-coding RNAs

Mrozowich, T.; Henrickson, A.; Demeler, B.; Patel, T. R.

10.1101/2020.01.10.901082 — biochemistry — Posted on 2020-01-10

2739 MicroRNA-574 Regulates FAM210A Expression and Influences Pathological Cardiac Remodeling

Wu, J.; Subbaiah, K. C. V.; Jiang, F.; Hedaya, O.; Mohan, A.; Yang, T.; Welle, K.; Ghaemmaghami, S.; Tang, W. H. W.; Small, E.; Yan, C.; Yao, P.

10.1101/2020.01.09.900712 — pathology — Posted on 2020-01-10

2740 Amino-alcohol Bio-conjugate of Naproxen Exhibits Anti-inflammatory Activity through NF-κB Signaling Pathway

Das, M. R.; Banerjee, A.; Sarkar, S.; Majumder, J.; Chakrabarti, S.; Jana, S. S.

10.1101/2020.01.10.901223 — molecular biology — Posted on 2020-01-10

2741 The electrically conductive pili of Geobacter soli

Zhuo, S.; Yang, G.; Zhuang, L.

10.1101/2020.01.09.901157 — microbiology — Posted on 2020-01-10

2742 Phylogenetic diversity and activity screening of cultivable actinobacteria isolated from marine sponges and associated environments from the western coast of India

Baig, U.; Dahanukar, N.; Shintre, N.; Holkar, K.; Pund, A. I.; Lele, U.; Gujarathi, T.; Patel, K.; Jakati, A.; Singh, R.; Vidwans, H.; Tamhane, V.; Deshpande, N.; Watve, M.

10.1101/2020.01.09.901108 — microbiology — Posted on 2020-01-10

2743 Gene size matters: What determines gene length in the human genome?

Lopes, I.; Altab, G.; Raina, P.; de Magalhaes, J. P.

10.1101/2020.01.10.901272 — genomics — Posted on 2020-01-10

2744 Synaptic protein DLG2 controls neurogenic transcriptional programs disrupted in schizophrenia and related disorders

Sanders, B.; D'Andrea, D.; Collins, M. O.; Rees, E. E.; Steward, T. G. J.; Zhu, Y.; Chapman, G.; Legge, S. E.; Pardinas, A. F.; Harwood, A. J.; Gray, W. P.; O'Donovan, M. C.; Owen, M. J.; Errington, A. C.; Blake, D. J.; Whitcomb, D. J.; Pocklington, A. J.; Shin, E.

10.1101/2020.01.10.898676 — genetics — Posted on 2020-01-10

2745 Hypercholesterolemia risk associated GPR146 is an orphan G-protein coupled receptor that regulates blood cholesterol level in human and mouse

Han, F.; Liu, X.; Chen, C.; Liu, Y.; Du, M.; Guan, Y.; Zhang, Y.; Wang, D.; Ahmed, M.; Li, X.; Liu, X.; Wu, Y.; Zhou, Y.; Liu, Y.; Song, B.-L.; He, H. H.; Wang, Y.

10.1101/2020.01.09.901041 — genetics — Posted on 2020-01-10

2746 Changes in partner traits drive variation in plant-nectar robber interactions across habitats

Fitch, G.; Vandermeer, J. H.

10.1101/2020.01.09.898692 — ecology — Posted on 2020-01-10

2747 Extensive nuclear gyration and pervasive non-genic transcription during primordial germ cell development in zebrafish

Redl, S.; de Jesus Domingues, A. M.; Moeckel, S.; Salvenmoser, W.; Mendez-Lago, M.; Ketting, R. F.

10.1101/2020.01.10.901306 — developmental biology — Posted on 2020-01-10

2748 A possible physical mechanism of the torque generation of the bacterial flagellar motor

Chou, Y.-c.

10.1101/2020.01.09.901124 — biophysics — Posted on 2020-01-10

2749 Comprehensive benchmarking of computational deconvolution of transcriptomics data

Avila Cobos, F.; Alquicira-Hernandez, J.; Powell, J.; Mestdagh, P.; De Preter, K.

10.1101/2020.01.10.897116 — bioinformatics — Posted on 2020-01-10

2750 Developmental hourglass and heterochronic shifts in fin and limb development

Onimaru, K.; Tatsumi, K.; Tanegashima, C.; Kadota, M.; Nishimura, O.; Kuraku, S.

10.1101/2020.01.10.901173 — evolutionary biology — Posted on 2020-01-10

2751 Photosynthetic protein classification using genome neighborhood-based machine learning feature

Sangphukieo, A.; Laomettachit, T.; Ruengjitchatchawalya, M.

10.1101/2020.01.09.898809 — bioinformatics — Posted on 2020-01-10

2752 Chroococcidiorella tianjinensis, gen. et sp. nov. (Trebouxiophyceae, Chlorophyta), a green alga arises from the cyanobacterium TDX16

Dong, Q.; Xing, X.-y.

10.1101/2020.01.09.901074 — plant biology — Posted on 2020-01-10

2753 The microbiome of captive hamadryas baboon

Li, X.; Trivedi, U.; Brejnrod, A. D.; Vestergaard, G.; Mortensen, M. S.; Bertelsen, M. F.; Sorensen, S. J.

10.1101/2020.01.10.901256 — microbiology — Posted on 2020-01-10

2754 Suppression of Cytotoxic T Cell Functions and Decreased Levels of Tissue Resident Memory T cell During H5N1 infection

Kandasamy, M.; Furlong, K.; Perez, J. T.; Manicassamy, S.; Manicassamy, B.

10.1101/2020.01.09.901132 — microbiology — Posted on 2020-01-10

2755 Propranolol and parathyroid hormone synergistically improve bone volume fraction by suppressing resorption

Treyball, A.; Bergeron, A. C.; Brooks, D. J.; Nevola, K. T.; Hashmi, H.; Nagano, K.; Barlow, D.; Houseknecht, K. L.; Baron, R.; Bouxsein, M.; Guntur, A. R.; Motyl, K. J.

10.1101/2020.01.08.898320 — physiology — Posted on 2020-01-10

2756 Phosphoglycerol-type wall- and lipoteichoic acids are enantiomeric polymers differentially cleaved by the stereospecific glycerophosphodiesterase GlpQ

Walter, A.; Unsleber, S.; Rismondo, J.; Jorge, A. M.; Peschel, A.; Grundling, A.; Mayer, C.

10.1101/2020.01.08.899310 — microbiology — Posted on 2020-01-10

2757 C-terminal eYFP fusion impairs Escherichia coli MinE function

Palanisamy, N.; Öztürk, M. A.; Di Ventura, B.

10.1101/2020.01.08.899393 — microbiology — Posted on 2020-01-10

2758 Neuroretinal-derived caveolin-1 promotes endotoxin-induced inflammation in the murine retina

Gurley, J.; Gmyrek, G.; McClellan, M. E.; Hauck, S. M.; Dozmorov, M.; Wren, J. D.; Carr, D. J. J.; Elliott, M. H.

10.1101/2020.01.08.899377 — cell biology — Posted on 2020-01-10

2759 Centrosome impairment causes DNA replication stress through MLK3/MK2 signaling and R-loop formation

Tayeh, Z.; Stegmann, K.; Kleeberg, A.; Friedrich, M.; Choo, J. A. M. Y.; Wollnik, B.; Dobbelstein, M.

10.1101/2020.01.09.898684 — cell biology — Posted on 2020-01-10

2760 Optogenetic low-frequency stimulation of dentate granule cells prevents seizure generation in experimental epilepsy

Paschen, E.; Elgueta, C.; Heining, K.; Vieira, D. M.; Orcinha, C.; Häussler, U.; Bartos, M.; Egert, U.; Janz, P.; Haas, C. A.

10.1101/2020.01.09.900084 — physiology — Posted on 2020-01-10

2761 Identification of a novel breathing circuit that controls pain and anxiety

Liu, S.; Ye, M.; Pao, G. M.; Song, S. M.; Jhang, J.; Han, S.

10.1101/2020.01.09.900738 — neuroscience — Posted on 2020-01-10

2762 Differences in memory for what, where, and when components of recently-formed episodes

Sakon, J. J.; Kiani, R.

10.1101/2020.01.09.901033 — neuroscience — Posted on 2020-01-10

2763 ECSIT prevents Alzheimer's disease pathology by regulating neuronal mitochondrial ROS and mitophagy

Lepelley, A.; Vaughn, L. S.; Staniszewski, A.; Zhang, H.; Du, F.; Koppensteiner, P.; Tomljanovic, Z.; Carneiro, F. R.; Teich, A. F.; Ninan, I.; Yan, S. S.; Postler, T. S.; Hayden, M. S.; Arancio, O.; Ghosh, S.

10.1101/2020.01.09.900407 — neuroscience — Posted on 2020-01-10

2764 Multiple resource use strategies confer resilience to the socio-ecosystem in a protected area in the Yucatan Peninsula, Mexico

Garcia Jacome, L. G.; Garcia-Frapolli, E.; Bonilla-Moheno, M.; Rangel Rivera, C.; Benitez, M.; Ramos-Fernandez, G.

10.1101/2020.01.08.897462 — ecology — Posted on 2020-01-10

2765 Gene Expression of Functionally-Related Genes Coevolves Across Fungal Species: Detecting Coevolution of Gene Expression Using Phylogenetic Comparative Methods

Cope, A. L.; O'Meara, B. C.; Gilchrist, M. A.

10.1101/844472 — evolutionary biology — Posted on 2020-01-10

2766 Diapause is not selected as a bet-hedging strategy in insects: a meta-analysis of reaction norm shapes

Joschinski, J.; Bonte, D.

10.1101/752881 — ecology — Posted on 2020-01-10

2767 Virtual screening of MAP-Tau protein inhibitors from Semecarpus anacardium Linn. leaf extract for cancer prevention

Singh, R. K.; Ranjan, A.; Tripathi, R.; Srivastava, A. K.; Singh, M.; Kumar, A.; Singh, A. K.; Dwivedi, K. N.; Atri, N.; Singh, S. K.

10.1101/2020.01.08.899708 — bioinformatics — Posted on 2020-01-10

2768 Ultra-high field imaging reveals increased whole brain connectivity underpins cognitive strategies that attenuate pain

Schulz, E.; Stankewitz, A.; Winkler, A. M.; Irving, S.; Witkovsky, V.; Tracey, I.

10.1101/802306 — neuroscience — Posted on 2020-01-10

2769 metabolisHMM: Phylogenomic analysis for exploration of microbial phylogenies and metabolic pathways

McDaniel, E. A.; Anantharaman, K.; McMahon, K.

10.1101/2019.12.20.884627 — bioinformatics — Posted on 2020-01-10

2770 Sequence representations and their utility for predicting protein-protein interactions

Kimothi, D.; Biyani, P.; Hogan, J. M.

10.1101/2019.12.31.890699 — bioinformatics — Posted on 2020-01-10

2771 Dissociable roles of central striatum and anterior lateral motor area in initiating and sustaining naturalistic behavior

Corbit, V.; Piantadosi, S. C.; Wood, J. T.; Liu, G.; Choi, C. J. Y.; Witten, I.; Gittis, A. H.; Ahmari, S. E.

10.1101/2020.01.08.899070 — neuroscience — Posted on 2020-01-10

2772 TractEM: Fast Protocols for Whole Brain Deterministic Tractography-Based White Matter Atlas

Bayrak, R. G.; Wang, X.; Schilling, K. G.; Greer, J. M.; Hansen, C. B.; Blaber, J. A.; Williams, O.; Beason-Held, L. L.; Resnick, S. M.; Rogers, B. P.; Landman, B. A.

10.1101/651935 — neuroscience — Posted on 2020-01-10

2773 The sodium leak channel complex is voltage sensitive and directly modulated by extracellular calcium

Chua, H. C.; Wulf, M.; Weidling, C.; Rasmussen, L. P.; Pless, S. A.

10.1101/740456 — neuroscience — Posted on 2020-01-10

2774 Identification of hidden population structure in time-scaled phylogenies

Volz, E.; Wiuf, C.; Grad, Y.; Frost, S.; Dennis, A.; Didelot, X.

10.1101/704528 — evolutionary biology — Posted on 2020-01-10

2775 Microtubule Probe for Correlative Super-Resolution Fluorescence and Electron Microscopy

Battaglia, X. T.; De Pace, C.; Ruiz-Perez, L.; Chen, B.; Su, R.; Zhang, M.; Zhang, R.; Zhang, Q.; Wang, Q.; Zhou, H.; Wu, J.; Battaglia, G.; Zhang, Z.; Tian, Y.

10.1101/351098 — cell biology — Posted on 2020-01-10

2776 Potential hydrodynamic cytoplasmic transfer between mammalian cells: Cell-projection pumping

Zoellner, H.; Paknejad, N.; Cornwell, J.; Chami, B.; Romin, Y.; Boyko, V.; Fujisawa, S.; Kelly, E.; Lynch, G. W.; Rogers, G.; Manova, K.; Moore, M. A.

10.1101/531798 — cell biology — Posted on 2020-01-10

2777 Limits in the detection of m6A changes using MeRIP/m6A-seq

McIntyre, A. B. R.; Gokhale, N. S.; Cerchietti, L.; Jaffrey, S. R.; Horner, S. M.; Mason, C. E.

10.1101/657130 — bioinformatics — Posted on 2020-01-10

2778 Reorganization of the Primate Dorsal Horn in Response to a Deafferentation Lesion Affecting Hand Function

Fisher, K. M.; Garner, J.; Darian-Smith, C. J.

10.1101/818716 — neuroscience — Posted on 2020-01-10

2779 Prefrontal deep projection neurons enable cognitive flexibility via persistent feedback monitoring

Spellman, T.; Svei, M.; Liston, C.

10.1101/828590 — neuroscience — Posted on 2020-01-10

2780 Evolution of gastrointestinal tract morphology and plasticity in cave-adapted Mexican tetra, Astyanax mexicanus

Riddle, M. R.; Damen, F.; Aspiras, A.; Tabin, J. A.; McGaugh, S.; Tabin, C.

10.1101/852814 — evolutionary biology — Posted on 2020-01-10

2781 The wild grape genome sequence provides insights into the transition from dioecy to hermaphroditism during grape domestication

Badouin, H.; Velt, A.; Gindraud, F.; Flutre, T.; Dumas, V.; Vautrin, S.; Marande, W.; Corbi, J.; Sallet, E.; Ganofsky, J.; Santoni, S.; Guyot, D.; Ricciardelli, E.; Jepsen, K.; Kafer, J.; Berges, H.; Duchene, E.; Picard, F.; Hugueney, P.; Tavares, R.; Bacilieri, R.; Rustenholz, C.; Marais, G. A.

10.1101/2020.01.07.897082 — evolutionary biology — Posted on 2020-01-10

2782 What would it take to describe the global diversity of parasites?

Carlson, C. J.; Phillips, A. J.; Dallas, T. A.; Alexander, L. W.; Phelan, A.; Bansal, S.

10.1101/815902 — ecology — Posted on 2020-01-10

2783 Curvature-sensitive trans-assembly of human Atg8-family proteins in autophagy-related membrane tethering

Taniguchi, S.; Toyoshima, M.; Takamatsu, T.; Mima, J.

10.1101/870857 — cell biology — Posted on 2020-01-10

2784 Heterogeneity in human hippocampal CaMKII transcripts reveals allosteric hub-dependent regulation

Sloutsky, R.; Dziedzic, N.; Dunn, M. J.; Bates, R.; Torres-Ocampo, A. P.; Boopathy, S.; Page, B.; Weeks, J. G.; Chao, L. H.; Stratton, M. M.

10.1101/721589 — biochemistry — Posted on 2020-01-10

2785 Brain connectivity during Alzheimer's disease progression and its cognitive impact in a transgenic rat model

Munoz-Moreno, E.; Tudela, R.; Lopez-Gil, X.; Soria, G.

10.1101/690180 — neuroscience — Posted on 2020-01-10

2786 The effects of habits on motor skill learning

Popp, N. J.; Yokoi, A.; Gribble, P. L.; Diedrichsen, J.

10.1101/338749 — neuroscience — Posted on 2020-01-10

2787 A novel workflow to improve multi-locus genotyping of wildlife species: an experimental set-up with a known model system

Gillingham, M.; Montero, B. K.; Wilhelm, K.; Grudzus, K.; Sommer, S.; Santos, P.

10.1101/638288 — molecular biology — Posted on 2020-01-10

2788 Genetic differentiation and intrinsic genomic features explain variation in recombination hotspots among cocoa tree populations

Schwarzkopf, E. J.; Motamayor, J. C.; Cornejo, O. E.

10.1101/482299 — genomics — Posted on 2020-01-10

2789 High-quality SNPs from genic regions highlight introgression patterns among European white oaks (Quercus petraea and Q. robur).

Lang, T.; Abadie, P.; Leger, V.; Decourcelle, T.; Frigerio, J.-M.; Burban, C.; Bodenes, C.; Guichoux, E.; Le Provost, G.; Robin, C.; Tani, N.; Leger, P.; Lepoittevin, C.; El Mujtar, V. A.; Hubert, F.; Tibbits, J.; Paiva, J.; Franc, A.; Raspail, F.; Mariette, S.; Reviron, M.-P.; Plomion, C.; Kremer, A.; Desprez-Loustau, M.-L.; Garnier-Gere, P.

10.1101/388447 — evolutionary biology — Posted on 2020-01-10

2790 Regional differences in the abiotic environment contribute to genomic divergence within a wild tomato species

Gibson, M. J.; Moyle, L. C.

10.1101/744797 — evolutionary biology — Posted on 2020-01-10

2791 Systemic loss of Sarm1 protects Schwann cells from chemotoxicity by delaying axon degeneration

Lopez-Schier, H.; Tian, W.; Czopka, T.

10.1101/493163 — cell biology — Posted on 2020-01-10

2792 Calcium imaging in freely-moving mice during electrical stimulation of deep brain structures

Trevathan, J. K.; Asp, A. J.; Nicolai, E. N.; Trevathan, J. M.; Kremer, N. A.; Kozai, T. D. Y.; Cheng, D.; Schachter, M. J.; Nassi, J. J.; Otte, S. L.; Parker, J. G.; Lujan, L.; Ludwig, K. A.

10.1101/460220 — bioengineering — Posted on 2020-01-10

2793 Rapid detection of Pecan Root-Knot Nematode, Meloidogyne partityla, in laboratory and field conditions using loop-mediated isothermal amplification

Waliullah, S.; Bell, J.; Stackhouse, T.; Jagdale, G.; Hajihassani, A.; Brenneman, T.; Ali, M. E.

10.1101/2020.01.09.900076 — plant biology — Posted on 2020-01-09

2794 Physiotherapist and Podiatrist Independent Prescribing in the United Kingdom: A quasi experimental study

Carey, N.; Edwards, J.; Otter, S.; Gage, H.; Williams, P.; Courtenay, M.; Moore, A.; Stenner, K.

10.1101/2020.01.09.900043 — scientific communication and education — Posted on 2020-01-09

2795 Peritonsillar abscess may not always be a complication of acute tonsillitis: A prospective cohort study

Sanmark, E.; Wiksten, J.; Välimaa, H.; Aaltonen, L.-M.; Ilmarinen, T.; Blomgren, K.

10.1101/2020.01.09.900068 — pathology — Posted on 2020-01-09

2796 Mathematical investigation of microbial quorum sensing under various flow conditions

Jung, H.; Meile, C.

10.1101/2020.01.09.900027 — microbiology — Posted on 2020-01-09

2797 Millipede genomes reveal unique adaptation of genes and microRNAs during myriapod evolution

Qu, Z.; Nong, W.; So, W. L.; Barton-Owen, T.; Li, Y.; Li, C.; Leung, T. C.; Baril, T.; Wong, A.; Swale, T.; Chan, T.; Hayward, A.; Ngai, S.-m.; Hui, J.

10.1101/2020.01.09.900019 — evolutionary biology — Posted on 2020-01-09

2798 A flexible workflow for simulating transcranial electric stimulation in healthy and lesioned brains

Kalloch, B.; Bazin, P.-L.; Villringer, A.; Sehm, B.; Hlawitschka, M.

10.1101/2020.01.09.900035 — neuroscience — Posted on 2020-01-09

2799 Decomposing Retrosynthesis into Reactive Center Prediction and Molecule Generation

Liu, X.; Li, P.; Song, S.

10.1101/677849 — bioengineering — Posted on 2020-01-09

2800 A novel cross talk of AtRAV1, an ethylene responsive transcription factor with MAP kinases imparts broad spectrum disease resistance in plants

Chandan, R. K.; Kumar, R.; Swain, D. M.; Ghosh, S.; Bhagat, P. K.; Patel, S.; Bagler, G.; Sinha, A. K.; Jha, G.

10.1101/2020.01.08.899690 — plant biology — Posted on 2020-01-09

2801 ADAM17-triggered TNF signalling protects the ageing Drosophila retina from lipid droplet mediated degeneration

Muliyil, S.; Levet, C.; Düsterhöft, S.; Dulloo, I.; Cowley, S.; Freeman, M.

10.1101/2020.01.09.900209 — neuroscience — Posted on 2020-01-09

2802 Therapy-induced lipid uptake and remodeling underpin ferroptosis hypersensitivity in prostate cancer

Tousignant, K. D.; Rockstroh, A.; Poad, B. L. J.; Talebi, A.; Young, R. R. S.; Fard, A. T.; Gupta, R.; Zang, T.; Wang, C.; Lehman, M. L.; Swinnen, J. V.; Blanksby, S. J.; Nelson, C. C.; Sadowski, M. C.

10.1101/2020.01.08.899609 — cancer biology — Posted on 2020-01-09

2803 CG14906 (mettl4) mediates m6A methylation of U2 snRNA in Drosophila

Gu, L.; Shi, Y.; Chen, H.; Tang, H.-W.; Wang, L.; Hong, J.; Wang, Z.; Shen, Z.; Lao, T.

10.1101/2020.01.09.890764 — biochemistry — Posted on 2020-01-09

2804 Dissecting the collateral damage of antibiotics on gut microbes

Maier, L.; Goemans, C. V.; Pruteanu, M.; Wirbel, J.; Kuhn, M.; Cacace, E.; Banerjee, T.; Anderson, E. E.; Milanese, A.; Loeber, U.; Forslund, S. K.; Patil, K. R.; Zeller, G.; Bork, P.; Typas, A.

10.1101/2020.01.09.893560 — microbiology — Posted on 2020-01-09

2805 Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes

Fujimoto, N.; He, Y.; D'Addio, M.; Tacconi, C.; Detmar, M.; Dieterich, L. C.

10.1101/2020.01.09.900241 — immunology — Posted on 2020-01-09

2806 A role for the MEGF6 gene in predisposition to osteoporosis

Teerlink, C. C.; Jurynec, M.; Hernandez, R.; Stevens, J.; Hughes, D.; Brunker, C.; Rowe, K.; Grunwald, D.; Facelli, J.; Cannon-Albright, L.

10.1101/2020.01.09.900696 — genetics — Posted on 2020-01-09

2807 Altered polarization of PAR-2 signaling during airway epithelial remodeling

Carey, R. M.; Freund, J. R.; Hariri, B. M.; Adappa, N. D.; Palmer, J. N.; Lee, R. J.

10.1101/2020.01.09.900555 — physiology — Posted on 2020-01-09

2808 Drug repurposing for mitochondrial diseases using a pharmacological model of complex I deficiency in the yeast Yarrowia lipolytica

Perlstein, E. O.

10.1101/2020.01.08.899666 — pharmacology and toxicology — Posted on 2020-01-09

2809 The neural computations for stimulus presence and modal identity diverge along a shared circuit

Tovar, D. A.; Noel, J.-P.; Ishizawa, Y.; Patel, S. R.; Eskandar, E.; Wallace, M. T.

10.1101/2020.01.09.900563 — neuroscience — Posted on 2020-01-09

2810 In vitro characterization of protein effector export in the bradyzoite stage of Toxoplasma gondii

Mayoral, J. A.; Shamamian, P.; Weiss, L. M.

10.1101/2020.01.08.899773 — microbiology — Posted on 2020-01-09

2811 Population variability in the generation and thymic selection of T-cell repertoires

Sethna, Z.; Isacchini, G.; Dupic, T.; Mora, T.; Walczak, A. M.; Elhanati, Y.

10.1101/2020.01.08.899682 — immunology — Posted on 2020-01-09

2812 Expression-Based Inference of Human Microbiome Metabolic Flux Patterns in Health and Disease

Wang, Y.; Gu, Z.

10.1101/2020.01.09.900761 — systems biology — Posted on 2020-01-09

2813 EEG correlates of physical effort and reward processing during reinforcement learning

Palidis, D. J.; Gribble, P.

10.1101/2020.01.09.900530 — neuroscience — Posted on 2020-01-09

2814 Limb contraction drives fear perception

Poyo Solanas, M.; Vaessen, M.; de Gelder, B.

10.1101/2020.01.09.899849 — neuroscience — Posted on 2020-01-09

2815 The effect of exercise on the protein profile of rat knee joint intra- and extra-articular ligaments

Ashraf Kharaz, Y.; Birch, H. L.; Chester, A.; Simpson, D.; Clegg, P.; Comerford, E.

10.1101/2020.01.09.900142 — molecular biology — Posted on 2020-01-09

2816 Bayesian genomic models boost prediction accuracy for resistance against Streptococcus agalactiae in Nile tilapia (Oreochromus nilioticus)

Joshi, R.; Skaarud, A.; Alvarez, A. T.; Moen, T.; Odegard, J.

10.1101/2020.01.09.900134 — genomics — Posted on 2020-01-09

2817 Cell segmentation using deep learning: comparing label and label-free approaches using hyper-labeled image stacks

Cameron, W. D.; Bui, C. V.; Bennett, A. M.; Chang, H. H.; Rocheleau, J. V.

10.1101/2020.01.09.900605 — bioengineering — Posted on 2020-01-09

2818 How can noise alter neurophysiology in order to improve human behaviour? A combined transcranial random noise stimulation and electroencephalography study

Sheffield, J. G.; Raz, G.; Sella, F.; Cohen Kadosh, R.

10.1101/2020.01.09.900118 — neuroscience — Posted on 2020-01-09

2819 Long-term nutrient enrichment of an oligotroph-dominated wetland increases bacterial diversity in bulk soils and plant rhizospheres

Bledsoe, R. B.; Goodwillie, C.; Peralta, A. L.

10.1101/2020.01.08.899781 — microbiology — Posted on 2020-01-09

2820 Two synthetic 18-way outcrossed populations of diploid budding yeast with utility for complex trait dissection

Linder, R. A.; Long, A. D.; Chakraborty, M.; Majumder, A.

10.1101/2020.01.09.900480 — genetics — Posted on 2020-01-09

2821 NOTCH inhibition promotes myoblast fusion by releasing HEYL repression on TMEM8C regulatory regions in foetal skeletal muscles

Esteves de Lima, J.; Blavet, C.; Bonnin, M.-A.; Hirsinger, E.; Havis, E.; DUPREZ, D.

10.1101/2020.01.09.900159 — developmental biology — Posted on 2020-01-09

2822 DDIEM: Drug Database for Inborn Errors of Metabolism

Abdelhakim, M.; McMurray, E.; Syed, A. R.; Kafkas, S.; Kamau, A. A.; Schofield, P. N.; Hoehndorf, R.

10.1101/2020.01.08.897223 — bioinformatics — Posted on 2020-01-09

2823 Structural basis of SALM3 dimerization and synaptic adhesion complex formation with PTPσ

Karki, S.; Shkumatov, A. V.; Bae, S.; Ko, J.; Kajander, T.

10.1101/2020.01.09.893701 — biochemistry — Posted on 2020-01-09

2824 Limited dispersal and an unexpected aggression pattern in a native supercolonial ant

Hakala, S. M.; Ittonen, M.; Seppae, P.; Helanterae, H.

10.1101/2020.01.09.899971 — animal behavior and cognition — Posted on 2020-01-09

2825 CRY1-CBS binding regulates circadian clock function and metabolism

Cal-Kayitmazbatir, S.; Kulkoyluoglu-Cotul, E.; Growe, J.; Selby, C. P.; Rhoades, S. D.; Malik, D.; Oner, H.; Asimgil, H.; Francey, L. J.; Sancar, A.; Kruger, W. D.; Hogenesch, J. B.; Weljie, A.; Anafi, R.; Kavakli, I. H.

10.1101/2020.01.09.898866 — molecular biology — Posted on 2020-01-09

2826 Disassembly and degradation of MinD oscillator complexes by Escherichia coli ClpXP

LaBreck, C. J.; Trebino, C. E.; Ferreira, C. N.; Morrison, J. J.; DiBiasio, E. C.; Conti, J.; Camberg, J. L.

10.1101/2020.01.09.899195 — microbiology — Posted on 2020-01-09

2827 A New Tree-Based Methodological Framework to Infer the Evolutionary History of Mesopolyploid Lineages: An Application to the Brassiceae Tribe (Brassicaceae).

Henocq, L.; Gallina, S.; Schmitt, E.; Castric, V.; Vekemans, X.; Poux, C.

10.1101/2020.01.09.900571 — evolutionary biology — Posted on 2020-01-09

2828 Ostrea edulis at shipwrecks in the Dutch North Sea

Coolen, J. W. P.; van Dongen, U.; Driessen, F. M. F.; Wurz, E.; Bergsma, J. H.; Olie, R. A.; Deden, B.; Bos, O. G.

10.1101/2020.01.09.883827 — ecology — Posted on 2020-01-09

2829 Succination of Dihydrolipoyllysine Succinyltransferase (DLST) Exacerbates Mitochondrial ATP Deficiency in a Mouse Model of Leigh Syndrome

Piroli, G. G.; Manuel, A. M.; Smith, H. H.; McCain, R. S.; Walla, M. D.; Frizzell, N.

10.1101/2020.01.09.900514 — biochemistry — Posted on 2020-01-09

2830 Required concentration index quantifies effective drug combinations against HCV infection

Iwami, S.; Kakizoe, Y.; Koizumi, Y.; Ikoma, Y.; Ohashi, H.; Wakita, T.; Watashi, K.

10.1101/2020.01.09.899807 — systems biology — Posted on 2020-01-09

2831 Improved, two-stage protein expression and purification via autoinduction of both autolysis and auto DNA/RNA hydrolysis conferred by phage lysozyme and DNA/RNA endonuclease

Menacho-Melgar, R.; Moreb, E. A.; Efromson, J. P.; Lynch, M. D.

10.1101/2020.01.09.900753 — synthetic biology — Posted on 2020-01-09

2832 Response of Pseudomonas aeruginosa to the innate immune system-derived oxidants hypochlorous acid and hypothiocyanous acid

Farrant, K. V.; Spiga, L.; Davies, J. C.; Williams, H. D.

10.1101/2020.01.09.900639 — microbiology — Posted on 2020-01-09

2833 Dual-light photodynamic therapy administered daily provides a sustained antibacterial effect on biofilm and prevents Streptococcus mutans adaptation

Nikinmaa, S.; Alapulli, H.; Auvinen, P.; Vaara, M.; Rantala, J.; Kankuri, E.; Sorsa, T.; Meurman, J.; Patila, T.

10.1101/2020.01.09.899963 — microbiology — Posted on 2020-01-09

2834 Silencing of Mu elements in maize involves distinct populations of small RNAs and distinct patterns of DNA methylation

Burgess, D.; Zhao, M.; Kim, S. Y.; Lisch, D.

10.1101/2020.01.09.900282 — genetics — Posted on 2020-01-09

2835 Evolution of contribution timing in public goods games

Morsky, B.; Smolla, M.; Akcay, E.

10.1101/2020.01.09.900670 — evolutionary biology — Posted on 2020-01-09

2836 Climate, species richness, and body size drive geographical variation in resource specialization of herbivorous butterflies

Nakadai, R.; Nyman, T.; Hashimoto, K.; Iwasaki, T.; Valtonen, A.

10.1101/2020.01.09.899922 — ecology — Posted on 2020-01-09

2837 Mutation of the Galectin-3 Glycan Binding Domain (Lgals3-R200S) Enhances Cortical Bone Expansion in Male and Trabecular Bone Mass in Female Mice

Maupin, K. A.; Dick, D.; VARI Vivarium and Transgenics Core, ; Williams, B. O.

10.1101/2020.01.09.900787 — developmental biology — Posted on 2020-01-09

2838 mRNA localization is linked to translation regulation in the Caenorhabditis elegans germ lineage

Parker, D. M.; Winkenbach, L. P.; Boyson, S. P.; Saxton, M. N.; Daidone, C.; Al-Mazaydeh, Z. A.; Nishimura, M. T.; Mueller, F.; Osborne Nishimura, E.

10.1101/2020.01.09.900498 — developmental biology — Posted on 2020-01-09

2839 Free Energy Landscape and Conformational Kinetics of Hoogsteen Base-Pairing in DNA vs RNA

Ray, D.; Andricioaei, I.

10.1101/2020.01.09.868018 — biophysics — Posted on 2020-01-09

2840 DNA Features Viewer, a sequence annotation formatting and plotting library for Python

Zulkower, V.; Rosser, S.

10.1101/2020.01.09.900589 — bioinformatics — Posted on 2020-01-09

2841 Auto-regulatory J-domain interactions control Hsp70 recruitment in the oligomeric DNAJB8 co-chaperone

Ryder, B. D.; Matlahov, I.; Bali, S.; Vaquer-Alicea, J.; Van der Wel, P.; Joachimiak, L. A.

10.1101/2020.01.09.899237 — biochemistry — Posted on 2020-01-09

2842 Sclerotinia sclerotiorum hijacks copper from its host for infection

Yijuan, D.; Mei, J.; Chai, Y.; Yang, W.; Mao, Y.; Yan, B.; Yu, Y.; Disi, J. O.; Rana, K.; Li, J.; Qian, W.

10.1101/2020.01.09.900217 — pathology — Posted on 2020-01-09

2843 Accumulation of salient events in sensory cortex activity predicts subjective time

Sherman, M. T.; Fountas, Z.; Seth, A. K.; Roseboom, W.

10.1101/2020.01.09.900423 — neuroscience — Posted on 2020-01-09

2844 NINJA: an inducible genetic model for creating neoantigens in vivo

Damo, M.; Fitzgerald, B.; Lu, Y.; Nader, M.; William, I.; Cheung, J.; Connolly, K. A.; Foster, G. G.; Akama-Garren, E.; Lee, D.-Y.; Chang, G. P.; Gocheva, V.; Schmidt, L. M.; Boileve, A.; Wilson, J. H.; Cui, C.; Monroy, I.; Gokare, P. R.; Cabeceiras, P.; Jacks, T.; Joshi, N. S.

10.1101/2020.01.09.900894 — immunology — Posted on 2020-01-09

2845 Full-length LINE-1s with functional ORFs are favoured by host-level selection in human genomes

Dohna, H.; Zhou, B.; Zhu, X.; Urban, A. E.

10.1101/2020.01.09.900191 — genetics — Posted on 2020-01-09

2846 Bovine viral diarrhoea virus loses quasispecies diversity rapidly in culture

Russell, G. C.; Zadoks, R. N.; Willoughby, K.; Bachofen, C.

10.1101/2020.01.09.900332 — evolutionary biology — Posted on 2020-01-09

2847 A semi-empirical aerodynamic model of insect flight forces

Taylor, G. K.; Walker, S. M.

10.1101/2020.01.09.900654 — biophysics — Posted on 2020-01-09

2848 Pathdict: Machine learning software predict Drug-Pathway interaction in human Based on drug simplified molecular-input line-entry system (SMILES)

Habib, P.; Alsamman, A. M.; Hassanein, S.; Hamwieh, A.

10.1101/2020.01.08.899005 — bioinformatics — Posted on 2020-01-09

2849 Towards Autonomous Intra-cortical Brain Machine Interfaces: Applying Bandit Algorithms for Online Reinforcement Learning

Shaikh, S.; So, R.; Sibindi, T.; Libedinsky, C.; Basu, A.

10.1101/2020.01.08.899641 — bioengineering — Posted on 2020-01-09

2850 Quantifying the spatiotemporal dynamics of IRES versus Cap translation with single-molecule resolution in living cells

Koch, A. L.; Aguilera, L.; Morisaki, T.; Stasevich, T. J.; Munsky, B. E.

10.1101/2020.01.09.900829 — biochemistry — Posted on 2020-01-09

2851 PPM-Decay: A Computational Model of Auditory Prediction with Memory Decay

Harrison, P. M. C.; Bianco, R.; Chait, M.; Pearce, M. T.

10.1101/2020.01.09.900266 — animal behavior and cognition — Posted on 2020-01-09

2852 Potent inhibitors of toxic alpha-synuclein oligomers identified via cellular time-resolved FRET biosensor.

Braun, A. R.; Liao, E. E.; Horvath, M.; Young, M. C.; Lo, C. H.; Brown, R.; Evans, M. D.; Luk, K.; Thomas, D. D.; Sachs, J. N.

10.1101/2020.01.09.900845 — neuroscience — Posted on 2020-01-09

2853 Protein Targets of Inositol Pyrophosphate (5-IP7) in the parasite Trypanosoma cruzi

Mantilla, B. S.; Brown, N.; Fiedler, D.; Docampo, R.

10.1101/2020.01.09.900860 — microbiology — Posted on 2020-01-09

2854 Extensive genome-wide association analyses identify genotype-by-environment interactions of growth traits in Simmental cattle

Braz, C. U.; Rowan, T. N.; Schnabel, R. D.; Decker, J. E.

10.1101/2020.01.09.900902 — genomics — Posted on 2020-01-09

2855 RAD sequencing data reveal a radiation of willow species (Salix L., Salicaceae) in the Hengduan Mountains and adjacent areas

He, L.; Wagner, N. D.; Hoerandl, E.

10.1101/2020.01.08.899534 — evolutionary biology — Posted on 2020-01-09

2856 Virtaul screening of MAP-Tau protein inhibitors from Semecarpus anacardium Linn. leaf extract for cancer prevention

Singh, R. K.; Ranjan, A.; Tripathi, R.; Srivastava, A. K.; Singh, M.; Kumar, A.; Singh, A. K.; Dwivedi, K. N.; Atri, N.; Singh, S. K.

10.1101/2020.01.08.899708 — bioinformatics — Posted on 2020-01-09

2857 CB1 receptor-mediated inhibitory LTD triggers presynaptic remodeling via protein synthesis and ubiquitination

Monday, H. R.; Bourdenx, M.; Jordan, B. A.; Castillo, P. E.

10.1101/2020.01.09.900464 — neuroscience — Posted on 2020-01-09

2858 Aberrant synaptic release underlies sleep/wake transition deficits in a mouse Vamp2 mutant

Banks, G. T.; Guillaumin, M. C. C.; Heise, I.; Lau, P.; Yin, M.; Bourbia, N.; Aguilar, C.; Bowl, M. R.; Esapa, C.; Brown, L. A.; Hasan, S.; Tagliatti, E.; Nocholson, E.; Bains, R. S.; Wells, S.; Vyazovskiy, V. V.; Volynski, K.; Peirson, S. N.; Nolan, P. M.

10.1101/2020.01.09.900233 — neuroscience — Posted on 2020-01-09

2859 FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell

RELIER, S.; RIPOLL, J.; GUILLORIT, H.; AMALRIC, A.; BOISSIERE, F.; VIALARET, J.; ATTINA, A.; DEBART, F.; CHOQUET, A.; MACARI, F.; SAMALIN, E.; VASSEUR, J.-J.; PANNEQUIN, J.; CRAPEZ, E.; HIRTZ, C.; RIVALS, E.; BASTIDE, A.; DAVID, A.

10.1101/2020.01.09.899724 — cancer biology — Posted on 2020-01-09

2860 G9a Promotes Breast Cancer Recurrence Through Repression of a Pro-inflammatory Program

Mabe, N. W.; Wolery, S. E.; Newcomb, R.; Meingasner, R. C.; Vilona, B. A.; LIN, C.-C.; Lupo, R.; Chi, J.-T. A.; Alvarez, J. V.

10.1101/2020.01.09.900183 — cancer biology — Posted on 2020-01-09

2861 A Simple and Robust Cell Based Assay for the Discovery of Novel Cytokinesis Inhibitors

Radnai, L.; Stremel, R. F.; Vaissiere, T.; Martin, W. H.; Rumbaugh, G.; Kamenecka, T. M.; Griffin, P.; Miller, C. A.

10.1101/2020.01.09.900365 — cell biology — Posted on 2020-01-09

2862 All-trans retinoic acid (ATRA) reduces proliferative capacity and Brachyury levels in chordoma cells

Robinson, H.; MacFarlane, R. J.; Wakeman, J. A.

10.1101/2020.01.09.897314 — cancer biology — Posted on 2020-01-09

2863 COP1 destabilizes DELLA proteins in Arabidopsis

Blanco-Tourinan, N.; Legris, M.; Minguet, E. G.; Costigliolo-Rojas, C.; Nohales, M. A.; Iniesto, E.; Garcia-Leon, M.; Pacin, M.; Heucken, N.; Blomeier, T.; Locascio, A.; Cerny, M.; Esteve-Bruna, D.; Diez-Diaz, M.; Brzobohaty, B.; Frerigmann, H.; Zurbriggen, M. D.; Kay, S. A.; Rubio, V.; Blazquez, M. A.; Casal, J. J.; Alabadi, D.

10.1101/2020.01.09.897157 — plant biology — Posted on 2020-01-09

2864 The cortical wiring scheme of hierarchical information processing

Paquola, C.; Seidlitz, J.; Benkarim, O.; Royer, J.; Klimes, P.; Bethlehem, R. A. I.; Lariviere, S.; Vos de Wael, R.; Hall, J.; Frauscher, B.; Smallwood, J.; Bernhardt, B.

10.1101/2020.01.08.899583 — neuroscience — Posted on 2020-01-09

2865 Context-modular memory networks support high-capacity, flexible, and robust associative memories

Podlaski, W. F.; Agnes, E. J.; Vogels, T. P.

10.1101/2020.01.08.898528 — neuroscience — Posted on 2020-01-09

2866 Cell-type specific impact of glucocorticoid receptor activation on the developing brain

Cruceanu, C.; Dony, L.; Kontira, A. C.; Fischer, D. S.; Roeh, S.; Di Giaimo, R.; Kyrousi, C.; Arloth, J.; Czamara, D.; Martinelli, S.; Wehner, S.; Breen, M. S.; Koedel, M.; Sauer, S.; Rex-Haffner, M.; Cappello, S.; Theis, F. J.; Binder, E.

10.1101/2020.01.09.897868 — neuroscience — Posted on 2020-01-09

2867 Hemoglobin Non-equilibrium Oxygen Dissociation Curve

Scrima, R.; Fugetto, S.; Capitanio, N.; Gatti, D. L.

10.1101/2020.01.09.900001 — biophysics — Posted on 2020-01-09

2868 Protein S-nitrosylation of Human Cytomegalovirus pp71 inhibits its ability to limit STING antiviral responses

Nukui, M.; Roche, K. L.; Jia, J.; Fox, P. L.; Murphy, E. A.

10.1101/2020.01.08.899757 — microbiology — Posted on 2020-01-09

2869 ModelTeller: model selection for optimal phylogenetic reconstruction using machine learning

Abadi, S.; Avram, O.; Rosset, S.; Pupko, T.; Mayrose, I.

10.1101/2020.01.09.899906 — evolutionary biology — Posted on 2020-01-09

2870 Investigating the impact of combination phage and antibiotic therapy: a modeling study

Banuelos, S.; Gulbudak, H.; Horn, M. A.; Huang, Q.; Nandi, A.; Ryu, H.; Segal, R.

10.1101/2020.01.08.899476 — microbiology — Posted on 2020-01-09

2871 Species tree disequilibrium positively misleads models of gene family evolution

Lauterbur, M. E.; Heder, S.; Yohe, L. R.; Davalos, L. M.

10.1101/2020.01.08.899518 — evolutionary biology — Posted on 2020-01-09

2872 Circadian Rhythm Is Disrupted by ZNF704 in Breast Carcinogenesis

Yang, C.; Wu, J.; Liu, X.; Wang, Y.; Liu, B.; Chen, X.; Wu, X.; Yan, D.; Han, L.; Liu, S.; Shan, L.; Shang, Y.

10.1101/2020.01.09.900548 — cancer biology — Posted on 2020-01-09

2873 fMRI signatures of motor sequence learning: A critical re-evaluation

Berlot, E.; Popp, N. J.; Diedrichsen, J.

10.1101/2020.01.08.899229 — neuroscience — Posted on 2020-01-09

2874 Mechanisms of interaction of staphylococcus aureus with human mesenchymal stem cells and their differentiated phenotypes

Khamees, N.; Hill, D. J.; Kafienah, W.

10.1101/2020.01.09.900373 — microbiology — Posted on 2020-01-09

2875 Damage repair versus aging in biofilms

Wright, R. J.; Clegg, R. J.; Coker, T. L.; Kreft, J.-U.

10.1101/2020.01.08.899740 — microbiology — Posted on 2020-01-09

2876 The conformational distribution of a major facilitator superfamily peptide transporter is modulated by the membrane composition

Lasitza Male, T.; Bartels, K.; Wiggers, F.; Rosenblum, G.; Jungwirth, J.; Hofmann, H.; Loew, C.

10.1101/2020.01.09.900316 — biophysics — Posted on 2020-01-09

2877 Directional motion of membrane vesicles on conical surfaces

Zhenpeng, G.

10.1101/2020.01.09.899997 — biophysics — Posted on 2020-01-09

2878 Geographic and environmental contributions to genomic divergence in mangrove forests

Silva, M. F. d.; Cruz, M. V.; Junior, J. d. D. V.; Mori, G. M.; Zucchi, M. I.; de Souza, A. P.

10.1101/2020.01.08.889717 — genomics — Posted on 2020-01-09

2879 Polymorphism of fecundity genes (BMP15 and GDF9) and their association with litter size in Bangladeshi prolific Black Bengal goat

Das, A.; Shaha, M.; Das Gupta, M.; Dutta, A.; Miazi, O. F.

10.1101/2020.01.08.899443 — genetics — Posted on 2020-01-09

2880 Portable Automated Rapid Testing ( PART ) for auditory research: Validation in a normal hearing population

Lelo de Larrea-Mancera, E. S.; Stavropoulos, T.; Hoover, E. C.; Eddins, D. A.; Gallun, F. J.; Seitz, A. R.

10.1101/2020.01.08.899088 — animal behavior and cognition — Posted on 2020-01-09

2881 A FOXO-dependent replication checkpoint restricts proliferation of damaged cells

Hornsveld, M.; Feringa, F. M.; Krenning, L.; van den Berg, J.; Smits, L. M. M.; Nguyen, N. B. T.; Rodriguez Colman, M. J.; Dansen, T. B.; Medema, R. H.; Burgering, B. M. T.

10.1101/2020.01.09.900225 — molecular biology — Posted on 2020-01-09

2882 On mechanisms of light-induced deformations in photoreceptors

Boyle, K. C.; Chen, Z. C.; Ling, T.; Pandiyan, V. P.; Kuchenbecker, J.; Sabesan, R.; Palanker, D.

10.1101/2020.01.08.897728 — biophysics — Posted on 2020-01-09

2883 Enriching and aggregating purple non-sulfur bacteria in an anaerobic sequencing-batch photobioreactor for nutrient capture from wastewater

Cerruti, M.; Stevens, B.; Ebrahimi, S.; Alloul, A.; Vlaeminck, S. E.; Weissbrodt, D. G.

10.1101/2020.01.08.899062 — bioengineering — Posted on 2020-01-09

2884 Discovery of a novel inhibitory neuron class, the L-Stellate cells of the cochlear nucleus

Ngodup, T.; Romero, G. E.; Trussell, L.

10.1101/2020.01.09.900092 — neuroscience — Posted on 2020-01-09

2885 Cannabis use is associated with sexually dimorphic changes in executive control of visuospatial decision-making

Banks, P. J.; Bennett, P. J.; Sekuler, A. B.; Gruber, A. J.

10.1101/2020.01.08.899526 — neuroscience — Posted on 2020-01-09

2886 Mass Spectrometry Imaging of Cocaine, Drug Removal and Methylphenidate AlterPhospholipids in Drosophila Brain

Philipsen, M. H.; Phan, N. T.; Fletcher, J. S.; Ewing, A. G.

10.1101/2020.01.08.899401 — neuroscience — Posted on 2020-01-09

2887 Bayesian inference for biophysical neuron models enables stimulus optimization for retinal neuroprosthetics

Oesterle, J.; Behrens, C.; Schroeder, C.; Herrmann, T.; Euler, T.; Franke, K.; Smith, R. G.; Zeck, G.; Berens, P.

10.1101/2020.01.08.898759 — neuroscience — Posted on 2020-01-09

2888 Assessment of Brain Glucose Metabolism Following Cardiac Arrest by FDG Positron Emission Tomography

Zhang, H. J.; Mitchell, S.; Fang, Y.-H.; Tsai, H.-M.; Piao, L.; Ousta, A.; Leoni, L.; Chen, C.-T.; Sharp, W. W.

10.1101/2020.01.08.899252 — neuroscience — Posted on 2020-01-09

2889 Regulating AMPK and insulin level by Vinegar, Swimming and Refeeding on High-Fat Diet Rats to Rebuild Lipid Homeostasis

Yang, Y.; Zhang, F.; Xiao, X.; Ma, C.; Liu, H.; Yang, Y.

10.1101/2020.01.08.899419 — molecular biology — Posted on 2020-01-09

2890 Short-term changes in polysaccharide utilization mechanisms of marine bacterioplankton during a spring phytoplankton bloom

Reintjes, G.; Fuchs, B. M.; Scharfe, M.; Wiltshire, K. H.; Amann, R.; Arnosti, C.

10.1101/2020.01.08.899153 — microbiology — Posted on 2020-01-09

2891 Swimming ghosts of the halophilic archaeon, Haloferax volcanii

Kinosita, Y.; Mikami, N.; Li, Z.; Braun, F.; Quax, T. E.; Does, C. v. d.; Ishmukhametov, R.; Albers, S.-V.; Berry, R.

10.1101/2020.01.08.899351 — microbiology — Posted on 2020-01-09

2892 Interruption of thymic activity in adults improves responses to tumor immunotherapy

Almeida-Santos, J.; Bergman, M.-L.; Cabral, I. A.; Demengeot, J.

10.1101/2020.01.08.899484 — immunology — Posted on 2020-01-09

2893 Molecular profiling of innate immune response mechanisms in ventilator-associated pneumonia

PATHAK, K. V.; McGilvrey, M. I.; Hu, C. K.; Garcia-Mansfield, K.; Lewandoski, K.; Eftekhari, Z.; Yuan, Y.-C.; Zenhausern, F.; Menashi, E.; Pirrotte, P.

10.1101/2020.01.08.899294 — immunology — Posted on 2020-01-09

2894 A hybrid optimal contribution approach to drive short-term gains while maintaining long-term sustainability in a modern plant breeding program

Santantonio, N.; Robbins, K. R.

10.1101/2020.01.08.899039 — genetics — Posted on 2020-01-09

2895 Nα-acetylation of EsxA is required for mycobacterial cytosolic translocation and virulence

Aguilera, J.; Karki, C. B.; Li, L.; Reyes, S. V.; Zhang, Q.; Arico, C.; Ouellet, H.; Sun, J.

10.1101/2020.01.08.899369 — biochemistry — Posted on 2020-01-09

2896 Partitioning gene-based variance of complex traits by gene score regression

Li, Y.; Li, S. Y.; Zhang, W.; Liu, T. A.

10.1101/2020.01.08.899260 — bioinformatics — Posted on 2020-01-09

2897 Expression-Based Inference of Cancer Metabolic Flux Differences

Wang, Y.; Gu, Z.

10.1101/2020.01.08.899047 — systems biology — Posted on 2020-01-09

2898 Semecarpus anacardium Linn. leaf extract exhibits activities against breast cancer and prolongs the survival of tumor bearing mice

Singh, R. K.; Ranjan, A.; Tripathi, R.; Verma, S. S.; Sharma, V.; Singh, M.; Gupta, S. C.; Singh, A. K.; Singh, S. K.

10.1101/2020.01.08.898940 — pharmacology and toxicology — Posted on 2020-01-09

2899 A Leptosphaeria maculans set of isolates characterised on all available differentials and used as control to identify virulence frequencies in a current French population

Bousset, L.; Ermel, M.; Delourme, R.

10.1101/2020.01.09.900167 — pathology — Posted on 2020-01-09

2900 Gene replacement therapy provides benefit in an adult mouse model of Leigh syndrome

Reynaud-Dulaurier, R.; Benegiamo, G.; Marrocco, E.; Al-Tannir, R.; Surace, E. M.; Auwerx, J.; Decressac, M.

10.1101/2020.01.08.894881 — neuroscience — Posted on 2020-01-09

2901 Theory of Visual Attention (TVA) in Action: Assessing Premotor Attention in Simultaneous Eye-Hand Movements

Kreyenmeier, P.; Deubel, H.; Hanning, N. M.

10.1101/2020.01.08.898932 — neuroscience — Posted on 2020-01-09

2902 Serum cytokine levels are modulated by specific frequencies, amplitudes, and pulse widths of vagus nerve stimulation

Tsaava, T.; Datta-Chaudhuri, T.; Addorisio, M. E.; Masi, E. B.; Silverman, H. A.; Newman, J. E.; Imperato, G. H.; Bouton, C. E.; Tracey, K. J.; Chavan, S. S.; Chang, E. H.

10.1101/2020.01.08.898890 — immunology — Posted on 2020-01-09

2903 Exploring the functional meaning of head shape disparity in aquatic snakes.

Segall, M.; Cornette, R.; Godoy-Diana, R.; Herrel, A.

10.1101/2020.01.08.899435 — evolutionary biology — Posted on 2020-01-09

2904 Transcriptome analysis reveals evolutionary co-option of neural development and signaling genes for the wing pigmentation pattern of the polka-dotted fruit fly.

Fukutomi, Y.; Kondo, S.; Toyoda, A.; Shigenobu, S.; Koshikawa, S.

10.1101/2020.01.09.899864 — developmental biology — Posted on 2020-01-09

2905 Multiple phosphatidylinositol(3)phosphate roles in retinal pigment epithelium membrane recycling

He, F.; Agosto, M. A.; Nichols, R. M.; Wensel, T. G.

10.1101/2020.01.09.899815 — cell biology — Posted on 2020-01-09

2906 Data augmentation based on dynamical systems for the classification of brain states

Sanz Perl, Y.; Pallacivini, C.; Perez Ipina, I.; Kringelbach, M. L.; Deco, G.; Laufs, H.; Tagliazucchi, E.

10.1101/2020.01.08.898999 — biophysics — Posted on 2020-01-09

2907 Crystal structure of calcium bound outer membrane phospholipase A (OmpLA) from Salmonella typhi and in silico anti-microbial screening

Perumal, P.; Raina, R.; Narayanan, S.; Arulandu, A.

10.1101/2020.01.08.898262 — biophysics — Posted on 2020-01-09

2908 The small protein RmpD drives hypermucoviscosity in Klebsiella pneumoniae

Walker, K. A.; Treat, L. P.; Miller, V. L.

10.1101/2020.01.08.899096 — microbiology — Posted on 2020-01-09

2909 In silico analyses reveal new putative Breast Cancer RNA-binding proteins

Guerrero, S.; Lopez-Cortes, A.; Garcia-Cardenas, J. M.; Armendariz-Castillo, I.; Zambrano, A. K.; Indacochea, A.; Perez-Villa, A.; Yumiceba, V.; Guevara-Ramirez, P.; Jacome-Alvarado, A.; Leone, P. E.; Paz-y-Mino, C.

10.1101/2020.01.08.898965 — cancer biology — Posted on 2020-01-09

2910 Modeling of Ion and Water Transport in the Biological Nanopore ClyA

Willems, K.; Ruic, D.; Lucas, F.; Barman, U.; Hofkens, J.; Maglia, G.; Van Dorpe, P.

10.1101/2020.01.08.897819 — biophysics — Posted on 2020-01-09

2911 A molecular mechanism by which amyloid-β induces transcriptional inactivation of CREB in Alzheimer's Disease

Grochowska, K. M.; Kaushik, R.; Gomes, G. M.; Raman, R.; Baer, J.; Bayraktar, G.; Samer, S.; Reyes-Resina, I.; Spilker, C.; Morawski, M.; Rossner, S.; Navarro Brugal, G.; Karpova, A.; Kreutz, M. R.

10.1101/2020.01.08.898304 — neuroscience — Posted on 2020-01-09

2912 Lack of intrinsic postzygotic isolation in haplodiploid male hybrids despite high genetic distance

Bendall, E.; Mattingly, K. M.; Moehring, A.; Linnen, C. R.

10.1101/2020.01.08.898957 — evolutionary biology — Posted on 2020-01-09

2913 The RNA of maize chlorotic mottle virus - the essential virus in maize lethal necrosis disease - is translated via a panicum mosaic virus-like cap-independent translation element

Carino, E. J.; Scheets, K.; Miller, W. A.

10.1101/2020.01.08.898825 — plant biology — Posted on 2020-01-09

2914 Mediodorsal and ventromedial thalamus engage distinct L1 circuits in the prefrontal cortex

Anastasiades, P. G.; Collins, D. P.; Carter, A. G.

10.1101/2020.01.08.898817 — neuroscience — Posted on 2020-01-09

2915 Separation or Integration of Sequential Arrays in VWM Depends On the interval Between Them

Li, Z.; Zhang, J.; Liang, T.; Ye, C.; Liu, Q.

10.1101/2020.01.08.814889 — neuroscience — Posted on 2020-01-09

2916 Dissociable roles of central striatum and anterior lateral motor area in initiating and sustaining naturalistic behavior

Corbit, V.; Piantadosi, S. C.; Wood, J. T.; Liu, G.; Choi, C. J. Y.; Witten, I.; Gittis, A. H.; Ahmari, S. E.

10.1101/2020.01.08.899070 — neuroscience — Posted on 2020-01-09

2917 Individual differences among deep neural network models

Mehrer, J.; Spoerer, C. J.; Kriegeskorte, N.; Kietzmann, T. C.

10.1101/2020.01.08.898288 — neuroscience — Posted on 2020-01-09

2918 GAPDH controls extracellular vesicle biogenesis and enhances therapeutic potential of EVs in silencing the Huntingtin gene in mice via siRNA delivery

Dar, G. H.; Mendes, C. C.; Kuan, W.-L.; Conceicao, M.; El-Andaloussi, S.; Mager, I.; Roberts, T. C.; Barker, R. A.; Goberdhan, D. C. I.; Wilson, C.; Wood, M. J. A.

10.1101/2020.01.09.899880 — neuroscience — Posted on 2020-01-09

2919 Bright and tunable far-red chemigenetic indicators

Deo, C.; Abdelfattah, A. S.; Bhargava, H. K.; Berro, A. J.; Falco, N.; Moeyaert, B.; Chupanova, M.; Lavis, L. D.; Schreiter, E. R.

10.1101/2020.01.08.898783 — molecular biology — Posted on 2020-01-09

2920 A novel calcium-concentrating compartment drives biofilm formation and persistent infections

Keren-Paz, A.; Cohen-Cymberknoh, M.; Kolodkin-Gal, D.; Karunker, I.; Dersch, S.; Wolf, S. G.; Olender, T.; Kartvelishvily, E.; Kapishnikov, S.; Green-Zelinger, P.; Shteinberg, M.; Zamir, G.; Gal, A.; Graumann, P.; Kerem, E.; Kolodkin-Gal, I.

10.1101/2020.01.08.898569 — microbiology — Posted on 2020-01-09

2921 Genomic structure, evolutionary origins, and reproductive function of a large amplified intrinsically disordered protein gene on the X chromosome (Laidx) in mice.

Arlt, M. F.; Brogley, M. A.; Stark-Dykema, E. R.; Hu, Y.-C.; Mueller, J. L.

10.1101/2020.01.08.898924 — genetics — Posted on 2020-01-09

2922 Three Rules Explain Transgenerational Small RNA Inheritance in C. elegans

Houri Zeevi, L.; Antonova, O.; Rechavi, O.

10.1101/2020.01.08.899203 — genetics — Posted on 2020-01-09

2923 Independent domestications shape the genetic pattern of a reproductive isolation system in rice

xun, X.; song, G.; fumin, Z.

10.1101/2020.01.08.898130 — evolutionary biology — Posted on 2020-01-09

2924 Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate.

Shah, P. N. M.; Filman, D. J.; Karunatilaka, K. S.; Hesketh, E. L.; Groppelli, E.; Strauss, M.; Hogle, J. M.

10.1101/2020.01.08.899112 — biophysics — Posted on 2020-01-09

2925 Hap10: reconstructing accurate and long polyploid haplotypes using linked reads

Majidian, S.; Kahaei, M. H.; de Ridder, D.

10.1101/2020.01.08.899013 — bioinformatics — Posted on 2020-01-09

2926 Red Panda: A novel method for detecting variants in single-cell RNA sequencing

Cornish, A.; Roychoudhury, S.; Sarma, K.; Pramanik, S.; Bhakat, K.; Mishra, N. K.; Guda, C.

10.1101/2020.01.08.898874 — bioinformatics — Posted on 2020-01-09

2927 NAChRDB: A Web Resource of Structure-Function Annotations to Unravel the Allostery of Nicotinic Acetylcholine Receptors

Chareshneu, A.; Pant, P.; Ramos, R. J. T.; Gökbel, T.; Ionescu, C.-M.; Koca, J.

10.1101/2020.01.08.898171 — bioinformatics — Posted on 2020-01-09

2928 UDP-glucose dehydrogenase Ugd in E. coli is activated by Gmd and RffD, is inhibited by CheY, and regulates swarming

Rodionova, I. A.; Zhang, Z.; Aboulwafa, M.; Saier, M. H.

10.1101/2020.01.08.899336 — biochemistry — Posted on 2020-01-09

2929 Structure of a consensus chitin-binding domain revealed by solution NMR

Heymann, D.; Mohanram, H.; Kumar, A.; Verma, C. S.; Lescar, J.; Miserez, A.

10.1101/2020.01.08.899344 — biochemistry — Posted on 2020-01-09

2930 An interaction network of RNA-binding proteins involved in Drosophila oogenesis

Bansal, P.; Madlung, J.; Schaaf, K.; Macek, B.; Bono, F.

10.1101/2020.01.08.899146 — biochemistry — Posted on 2020-01-09

2931 A phospho-switch in the N-terminus of NRT2.1 affects nitrate uptake by controlling the interaction of NRT2.1 with NAR2.1

Li, Z.; Wu, X. N.; Jacquot, A.; Lejay, L.; Schulze, W. X.

10.1101/2020.01.08.898254 — plant biology — Posted on 2020-01-09

2932 Multi-scalar Approaches to the stable isotope ecology of late Quaternary Proboscideans in the Midcontinent

Widga, C.; Hodgins, G.; Kolis, K.; Lengyel, S. N.; Saunders, J. J.; Walker, J. D.; Wanamaker, A. D.

10.1101/2020.01.08.896647 — paleontology — Posted on 2020-01-09

2933 Acute Stress Reduces Reward-Related Neural Activity: Evidence from the Reward Positivity

Burani, K.; Gallyer, A. J.; Ryan, J.; Jordan, C.; Joiner, T. E.; Hajcak, G.

10.1101/2020.01.08.898593 — neuroscience — Posted on 2020-01-09

2934 A working memory intervention weakens the reconsolidation of a threat memory and its biases processing towards threat.

Picco, S.; Bavassi, L.; Fernandez, R. S.; Pedreira, M. E.

10.1101/2020.01.08.898643 — neuroscience — Posted on 2020-01-09

2935 A Bayesian Multi-Task Approach for Detecting Global Microbiome Associations

Hatami, F.; Beamish, E.; Rigby, R.; Dondelinger, F.

10.1101/2020.01.08.897538 — microbiology — Posted on 2020-01-09

2936 Using regions of homozygosity to evaluate the use of dogs as preclinical models in human drug development

Smieszek, S. P.; Polymeropoulos, M. H.

10.1101/2020.01.08.898916 — genomics — Posted on 2020-01-09

2937 Proteomics dissection of cardiac protein profiles of humans and model organisms

Linscheid, N.; Santos, A.; Poulsen, P. C.; Mills, R. W.; Stolte, C.; Leurs, U.; Ye, J. Z.; Calloe, K.; Thomsen, M. B.; Bentzen, B. H.; Lundegaard, P. R.; Olesen, M. S.; Jensen, L. J.; Olsen, J. V.; Lundby, A.

10.1101/2020.01.08.897595 — systems biology — Posted on 2020-01-09

2938 Sucrose promotes etiolated stem branching through activation of cytokinin accumulation followed by vacuolar invertase activity

Salam, B. B.; Barbier, F. F.; Danieli, R.; Ziv, C.; Spichal, L.; Teper-Bamnolker, P.; Jiang, J.; Ori, N.; Beveridge, C.; Eshel, D.

10.1101/2020.01.08.897009 — plant biology — Posted on 2020-01-09

2939 Discriminant Analysis of Principle Component analyses of Physiological Data.

Haidar, O.; Ball, S. T. M.; Barrett-Jolley, R.

10.1101/2020.01.09.899898 — physiology — Posted on 2020-01-09

2940 Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells

Pedersen, M. F.; Moller, T. C.; Seiersen, S. D.; Mathiesen, J. M.; Bouvier, M.; Bräuner-Osborne, H.

10.1101/2020.01.08.898338 — pharmacology and toxicology — Posted on 2020-01-09

2941 Neuronal dynamics of signal selective motor plan cancellation in the macaque dorsal premotor cortex

Giarrocco, F.; Bardella, G.; Giamundo, M.; Fabbrini, F.; Brunamonti, E.; Pani, P.; Ferraina, S.

10.1101/2020.01.08.897397 — neuroscience — Posted on 2020-01-09

2942 More than words: The online orchestration of word predictability, prosody, gesture, and mouth movements during natural language comprehension

Zhang, Y.; Frassinelli, D.; Tuomainen, J.; Skipper, J. I.; Vigliocco, G.

10.1101/2020.01.08.896712 — neuroscience — Posted on 2020-01-09

2943 Vitamin B12 is neuroprotective in experimental pneumococcal meningitis through modulation of hippocampal DNA methylation

de Queiroz, K. B.; Cavalcante-Silva, V.; Lopes, F. L.; Rocha, G. A.; D'Almeida, V.; Coimbra, R. S.

10.1101/2020.01.08.898635 — neuroscience — Posted on 2020-01-09

2944 Molecular Mechanisms of Non-ionotropic NMDA Receptor Signaling

Stein, I. S.; Park, D. K.; Jahncke, J. N.; Flores, J. C.; Zito, K.

10.1101/2020.01.08.898080 — neuroscience — Posted on 2020-01-09

2945 The effect of counterfactual information on outcome value coding in medial prefrontal and cingulate cortex: from an absolute to a relative neural code.

Pischedda, D.; Palminteri, S.; Coricelli, G.

10.1101/2020.01.08.898841 — neuroscience — Posted on 2020-01-09

2946 Assessing the Intra- and Inter-Subject Reliability of the Perturbational Complexity Index (PCI) of Consciousness for Three Brain Regions Using TMS-EEG

Caulfield, K. A.; Savoca, M. T.; Lopez, J. W.; Summers, P. M.; Li, X.; Fecchio, M.; Casarotto, S.; Massimini, M.; George, M. S.

10.1101/2020.01.08.898775 — neuroscience — Posted on 2020-01-09

2947 Regulation of canonical Wnt signalling by ciliary protein MKS1 and Ubiquitin Proteasome System component UBE2E1.

Szymanska, K.; Boldt, K.; Logan, C. V.; Ueffing, M.; Zeqiraj, E.; Wheway, G.; Johnson, C. A.

10.1101/2020.01.08.897959 — molecular biology — Posted on 2020-01-09

2948 Catabolism of 3-hydroxypyridine by Ensifer adhaerens HP1: a novel four-component gene encoding 3-hydroxypyridine dehydrogenase HpdA catalyzes the first step of biodegradation

Wang, H.; Wang, X.; Ren, H.; Wang, X.; Lu, Z.

10.1101/2020.01.08.898148 — microbiology — Posted on 2020-01-09

2949 The draft genome of the endangered, relictual plant Kingdonia uniflora (Circaeasteraceae, Ranunculales) reveals potential mechanisms and perils of evolutionary specialization

Sun, Y.; Deng, T.; zhang, A.; Moore, M. J.; Landis, J. B.; Lin, N.; Zhang, H.; Zhang, X.; Huang, J.; Zhang, X.; Sun, H.; Wang, H.

10.1101/2020.01.08.898460 — genomics — Posted on 2020-01-09

2950 Bacterial carotenoids suppress Caenorhabditis elegans surveillance and defense of translational dysfunction

Govindan, J. A.; Jayamani, E.; Lelyveld, V.; Szostak, J. W.; Ruvkun, G.

10.1101/2020.01.08.898668 — genomics — Posted on 2020-01-09

2951 Modeling the immunological pre-adaptation of HIV-1

van Dorp, C. H.; van Boven, M.; De Boer, R. j.

10.1101/2020.01.08.897983 — evolutionary biology — Posted on 2020-01-09

2952 Does seed mass drive interspecies variation in the effect of management practices on weed demography?

Kazakou, E.; Fried, G.; Cheptou, P.-O.; Gimenez, O.

10.1101/2020.01.08.898247 — ecology — Posted on 2020-01-09

2953 Multiple resource use strategies confer resilience to the socio-ecosystem in a protected area in the Yucatan Peninsula, Mexico

Garcia Jacome, L. G.; Garcia-Frapolli, E.; Bonilla-Moheno, M.; Rangel Rivera, C.; Bentiez, M.; Ramos-Fernandez, G.

10.1101/2020.01.08.897462 — ecology — Posted on 2020-01-09

2954 KLF4 coordinates corneal epithelial apicobasal polarity and plane of cell division, and is downregulated in ocular surface squamous neoplasia

Tiwari, A.; Swamynathan, S.; Jhanji, V.; Swamynathan, S. K.

10.1101/2020.01.08.899385 — cell biology — Posted on 2020-01-09

2955 Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy

Geck, R. C.; Foley, J. R.; Murray Stewart, T. R.; Asara, J. M.; Casero, R. A.; Toker, A.

10.1101/2020.01.08.899492 — cancer biology — Posted on 2020-01-09

2956 Conserved and divergent features of DNA methylation in embryonic stem cell-derived neurons

Martin, S.; Poppe, D.; Olova, N.; O'Leary, C.; Ivanova, E.; Pflueger, J.; Dechka, J.; Simmons, R. K.; Cooper, H. M.; Reik, W.; Lister, R.; Wolvetang, E. J.

10.1101/2020.01.08.898429 — genomics — Posted on 2020-01-09

2957 Over-Confluence of expanded bone marrow mesenchymal stem cells ameliorates their chondrogenic capacity in 3D cartilage tissue engineering

Tucker, D.; Still, K.; Blom, A.; Hollander, A. P.; Kafienah, W.

10.1101/2020.01.08.897645 — cell biology — Posted on 2020-01-09

2958 Ubiquitous overexpression of CXCL12 confers radiation protection and enhances mobilization of hematopoietic stem and progenitor cells

Forsberg, C.

10.1101/2020.01.08.899427 — cell biology — Posted on 2020-01-09

2959 Development of the yeast Saccharomyces cerevisiae as a biosensor for the toxicity detection of toxic substances

GONG, L.; Yang, G.; Yang, B.; Gu, J.

10.1101/2020.01.07.898106 — cell biology — Posted on 2020-01-09

2960 Inferring Disease-Associated Piwi-Interacting RNAs via Graph Attention Networks

Zheng, K.; You, Z.-H.; wang, l.; Wong, L.; Chen, Z.-H.; Jiang, H.-J.

10.1101/2020.01.08.898155 — bioinformatics — Posted on 2020-01-09

2961 Tissue engineered model of hepatic breast cancer micrometastasis shows host-dependent colonization patterns and drug responses

Guller, A. E.; Rozova, V. S.; Kuschnerus, I.; Khabir, Z.; Nadort, A.; Garcia-Bennett, A. E.; Liang, L.; Qian, Y.; Goldys, E. M.; Zvyagin, A. V.

10.1101/2020.01.08.898163 — bioengineering — Posted on 2020-01-09

2962 Sound context modulates perceived vocal emotion

Liuni, M.; Ponsot, E.; Bryant, G. A.; Aucouturier, J.-J.

10.1101/2020.01.08.898205 — animal behavior and cognition — Posted on 2020-01-09

2963 Changes in the gene expression profile during spontaneous migraine attacks

Kogelman, L. J. A.; Falkenberg, K.; Buil, A.; Erola, P.; Courraud, J.; Laursen, S. S.; Michoel, T.; Olesen, J.; Hansen, T. F.

10.1101/2020.01.08.898239 — genomics — Posted on 2020-01-09

2964 The Gossypium longicalyx genome as a resource for cotton breeding and evolution

Grover, C. E.; Pan, M.; Yuan, D.; Arick, M. A.; Hu, G.; Brase, L.; Stelly, D. M.; Lu, Z.; Schmitz, R. J.; Peterson, D. G.; Wendel, J. F.; Udall, J. A.

10.1101/2020.01.08.898908 — genomics — Posted on 2020-01-09

2965 Three dimensional parallelized RESOLFT nanoscopy for volumetric live cell imaging

Boden, A.; Pennacchietti, F.; Testa, I.

10.1101/2020.01.09.898510 — biophysics — Posted on 2020-01-09

2966 OvirusTdb: A Repository of Oncolytic Viruses used in Cancer Treatment

Lathwal, A.; Kumar, R.; Raghava, G. P. S.

10.1101/2020.01.08.896720 — bioinformatics — Posted on 2020-01-09

2967 A strategy for complete telomere-to-telomere assembly of ciliate macronuclear genome using ultra-high coverage Nanopore data

Wang, G.; Chai, X.; Zhang, J.; Yang, W.; Jiang, C.; Chen, K.; Miao, W.; Xiong, J.

10.1101/2020.01.08.898502 — genomics — Posted on 2020-01-09

2968 Intergenic RNA mainly derives from nascent transcripts of known genes

Agostini, F.; Zagalak, J. A.; Attig, J.; Ule, J.; Luscombe, N. M.

10.1101/2020.01.08.898478 — genomics — Posted on 2020-01-09

2969 A new long-read RNA-seq analysis approach identifies and quantifies novel transcripts of very large genes

Uapinyoying, P. B.; Goecks, J.; Knoblach, S.; Panchapakesan, K.; Bonnemann, C.; Partridge, T.; Jaiswal, J.; Hoffman, E.

10.1101/2020.01.08.898627 — genomics — Posted on 2020-01-09

2970 A novel transcriptional signalling pathway mediated by the trafficking protein Ambra1 via scaffolding Atf2 complexes

Schoenherr, C.; Byron, A.; Frame, M. C.

10.1101/2020.01.08.899328 — cell biology — Posted on 2020-01-09

2971 Homogeneous multifocal excitation for high-throughput super-resolution imaging

Mahecic, D.; Gambarotto, D.; Douglass, K. M.; Fortun, D.; Banterle, N.; Le Guennec, M.; Ibrahim, K. A.; Gonczy, P.; Hamel, V.; Guichard, P.; Manley, S.

10.1101/2020.01.08.895565 — biophysics — Posted on 2020-01-09

2972 Microbial diversity characterization of seawater in a pilot study using Oxford Nanopore Technologies long-read sequencing

Liem, M.; Henkel, C.; Regensburg, T.; Spaink, H. P.

10.1101/2020.01.08.898312 — bioinformatics — Posted on 2020-01-09

2973 cGAS, a DNA Sensor, Promotes Inflammatory Responses in Huntington Disease

Sharma, M.; Rajendrarao, S.; Shahani, N.; Ramirez Jarquin, U. N.; Subramaniam, S.

10.1101/2020.01.08.898718 — neuroscience — Posted on 2020-01-09

2974 Functional redundancy and crosstalk between flavodiiron proteins and NDH-1 in Synechocystis sp. PCC 6803

Nikkanen, L. E.; Santana Sanchez, A. I.; Ermakova, M.; Rogner, M.; Cournac, L.; Allahverdiyeva, Y.

10.1101/2019.12.23.886929 — plant biology — Posted on 2020-01-09

2975 CD4+ follicular helper-like T cells are key players in anti-tumor immunity

Singh, D.; Ganesan, A. P.; Panwar, B.; Eschweiler, S.; Hanley, C.; Madrigal, A.; Ramirez Suastegui, C.; Wang, A.; Clarke, J.; Wood, O.; Garrido-Martin, E. M.; Chee, S.; Seumois, G.; Belanger, S.; Alzetani, A.; Woo, E.; Friedmann, P.; Crotty, S.; Thomas, G.; Sanchez-Elsner, T.; Ay, F.; Ottensmeier, C.; Vijayanand, P.

10.1101/2020.01.08.898346 — immunology — Posted on 2020-01-09

2976 The Gene-Rich Genome of the Scallop Pecten maximus

Kenny, N. J.; McCarthy, S. A.; Dudchenko, O.; James, K.; Betteridge, E.; Corton, C.; Dolucan, J.; Mead, D.; Oliver, K.; Omer, A. D.; Pelan, S.; Ryan, Y.; Sims, Y.; Skelton, J.; Smith, M.; Torrance, J.; Weisz, D.; Wipat, A.; Aiden, E. L.; Howe, K.; Williams, S. T.

10.1101/2020.01.08.887828 — genomics — Posted on 2020-01-09

2977 Comparison of two individual-based model simulators for HIV epidemiology in a population with HSV-2 using as case study Yaounde-Cameroon, 1989-2005

Hendrickx, D. M.; Sousa, J.; Libin, P. J.; Delva, W.; Liesenborgs, J.; Hens, N.; Müller, V.; Vandamme, A.-M.

10.1101/637389 — epidemiology — Posted on 2020-01-09

2978 Different salicylic and jasmonic acids imbalances are involved in the oxidative stress-mediated cell death, induced by fumonisin B1 in maize seedlings with contrasting resistance to Fusarium verticillioides ear rot in the field.

Otaiza Gonzalez, S. N.; Mary, V.; Arias, S.; Bertrand, L.; Velez, P.; Rodriguez, M. G.; Rubinstein, H.; Theumer, M.

10.1101/2019.12.25.882597 — plant biology — Posted on 2020-01-09

2979 Interplay between the paradox of enrichment and nutrient cycling in food webs

Quevreux, P.; Barot, S.; Thebault, E.

10.1101/276592 — ecology — Posted on 2020-01-09

2980 MSIsensor-pro: fast, accurate and matched-normal-sample-free detection of microsatellite instability

Jia, P.; Yang, X.; Guo, L.; Liu, B.; Lin, J.; Liang, H.; Sun, J.; Zhang, C.; Ye, K.

10.1101/2020.01.08.899633 — bioinformatics — Posted on 2020-01-09

2981 Fate mapping quantifies the dynamics of B cell development and activation throughout life

Verheijen, M.; Rane, S.; Yates, A. J.; Seddon, B.

10.1101/871624 — immunology — Posted on 2020-01-09

2982 Single Cell Analysis Reveals Partial Reactivation of X-chromosome Instead of chromosome-wide dampening in Naive Human Pluripotent Stem Cells

Mandal, S.; Chandel, D.; Kaur, H.; Majumdar, S.; Arava, M.; Gayen, S.

10.1101/697565 — genetics — Posted on 2020-01-09

2983 Unidirectional response to bidirectional selection on body size. I. Phenotypic, life history and endocrine response.

Renneville, C.; Millot, A.; Agostini, S.; Carmignac, D.; Maugars, G.; Dufour, S.; Le Rouzic, A.; Edeline, E.

10.1101/498683 — evolutionary biology — Posted on 2020-01-09

2984 Evolutionary reticulation makes an important contribution to Amazonian tree diversity

Schley, R. J.; Pennington, T.; Perez-Escobar, O. A.; Helmstetter, A. J.; de la Estrella, M.; Larridon, I.; Sabino Kikuchi, I. A. B.; Barraclough, T. G.; Forest, F.; Klitgaard, B. B.

10.1101/2019.12.12.873927 — evolutionary biology — Posted on 2020-01-09

2985 Learning steers the ontogeny of an efficient hunting sequence in zebrafish larvae.

Lagogiannis, K.; Diana, G.; Meyer, M. P.

10.1101/2019.12.19.883157 — animal behavior and cognition — Posted on 2020-01-09

2986 Intramembrane protease RHBDL4 cleaves subunits of the oligosaccharyltransferase complex to target them for ER-associated degradation

Knopf, J. D.; Landscheidt, N.; Pegg, C. L.; Schulz, B. L.; Kuehnle, N.; Chao, C.-W.; Huck, S.; Lemberg, M. K.

10.1101/850776 — cell biology — Posted on 2020-01-09

2987 Learning cognitive maps for vicarious evaluation

Rikhye, R. V.; Gothoskar, N.; Guntupalli, J. S.; Dedieu, A.; Lazaro-Gredilla, M.; George, D.

10.1101/864421 — neuroscience — Posted on 2020-01-09

2988 Genomic surveillance enables suitability assessment of Salmonella gene targets used for culture-independent diagnostic testing

Rockett, R. J.; Arnott, A.; Wang, Q.; Howard, P.; Sintchenko, V.

10.1101/2020.01.07.898015 — microbiology — Posted on 2020-01-09

2989 Coping with Pleistocene climatic fluctuations: demographic responses in remote endemic reef fishes

Delrieu-Trottin, E.; Hubert, N.; Giles, E. C.; Chifflet-Belle, P.; Suwalski, A.; Neglia, V.; Rapu-Edmunds, C.; Mona, S.; Saenz-Agudelo, P.

10.1101/672774 — genomics — Posted on 2020-01-09

2990 CODC: A copula based model to identify differential coexpression.

Ray, S.; Lall, S.; Bandyopadhyay, S.

10.1101/725887 — bioinformatics — Posted on 2020-01-09

2991 Systemic Brain Tumor Delivery of Synthetic Protein Nanoparticles for Glioblastoma Therapy

Gregory, J. V.; Kadiyala, P.; Doherty, R.; Cadena, M.; Habeel, S.; Ruoslahti, E.; Lowenstein, P. R.; Castro, M. G.; Lahann, J.

10.1101/862581 — bioengineering — Posted on 2020-01-09

2992 Learning Divisive Normalization in Primary Visual Cortex

Burg, M. F.; Cadena, S. A.; Denfield, G. H.; Walker, E. Y.; Tolias, A. S.; Bethge, M.; Ecker, A. S.

10.1101/767285 — neuroscience — Posted on 2020-01-09

2993 Improving the sensitivity of cluster-based statistics for fMRI data

Geerligs, L.; Maris, E.

10.1101/2020.01.06.896167 — neuroscience — Posted on 2020-01-09

2994 Functional connectome contractions in temporal lobe epilepsy: microstructural underpinnings and associations to surgical outcome

Lariviere, S.; Wang, Y.; Vos de Wael, R.; Frauscher, B.; Wang, Z.; Bernasconi, A.; Bernasconi, N.; Schrader, D.; Zhang, Z.; Bernhardt, B.

10.1101/756494 — neuroscience — Posted on 2020-01-09

2995 cAMP-Fyn signaling in the dorsomedial striatum direct pathway drives excessive alcohol use

Ehinger, Y.; Morisot, N.; Sakhai, S.; Phamluong, K.; Adrover, M.; Alvarez, V.; Ron, D.

10.1101/2020.01.07.898023 — neuroscience — Posted on 2020-01-09

2996 Statistical power: implications for planning MEG studies

Chaumon, M.; Puce, A.; George, N.

10.1101/852202 — neuroscience — Posted on 2020-01-09

2997 Dopamine manipulations modulate paranoid social inferences in healthy people.

Barnby, J. M.; Bell, V.; Deeley, Q.; Mehta, M. A.

10.1101/2019.12.18.874255 — neuroscience — Posted on 2020-01-09

2998 Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early genes.

Lin, Y.-T.; Chiweshe, S.; McCormick, D.; Raper, A.; Wickenhagen, A.; DeFilippis, V. R.; Gaunt, E.; Simmonds, P.; Wilson, S. J.; Grey, F.

10.1101/2020.01.07.897132 — microbiology — Posted on 2020-01-09

2999 Defining the molecular state of human cancer

Sahu, B.; Pihlajamaa, P.; Zhang, K.; Palin, K.; Ahonen, S.; Cervera, A.; Ristimaki, A.; Aaltonen, L.; Hautaniemi, S.; Taipale, J.

10.1101/525600 — cancer biology — Posted on 2020-01-09

3000 Citrullination of pyruvate kinase by PADI1 and PADI3 regulates glycolysis and cancer cell proliferation.

Davidson, I.; Coassolo, S.; Davidson, G.; Negroni, L.; Gambi, G.; Daujat, S.; Romier, C.

10.1101/718486 — cancer biology — Posted on 2020-01-09

3001 The ELIXIR Core Data Resources: fundamental infrastructure for the life sciences

Drysdale, R.; Cook, C. E.; Petryszak, R.; Baillie Gerritsen, V.; Barlow, M.; Gasteiger, E.; Gruhl, F.; Haas, J.; Lanfear, J.; Lopez, R.; Redaschi, N.; Stockinger, H.; Teixeira, D.; Venkatesan, A.; Core Data Resource Forum, E.; Blomberg, N.; Durinx, C.; McEntyre, J.

10.1101/598318 — bioinformatics — Posted on 2020-01-09

3002 Loading effects on the performance of needle free jet injections in different skin models

Rohilla, P.; Lawal, I.; Le Blanc, A.; O'Brien, V.; Weeks, C.; Tran, W.; Rane, Y.; Khusnatdinov, E.; Marston, J.

10.1101/853481 — bioengineering — Posted on 2020-01-09

3003 Heterogeneity in human hippocampal CaMKII transcripts reveals allosteric hub-dependent regulation

Sloutsky, R.; Dziedzic, N.; Dunn, M. J.; Bates, R.; Torres-Ocampo, A. P.; Boopathy, S.; Page, B.; Weeks, J. G.; Chao, L. H.; Stratton, M. M.

10.1101/721589 — biochemistry — Posted on 2020-01-09

3004 Contribution of self- and other-regarding motives to (dis)honesty

Shuster, A.; Levy, D. J.

10.1101/590208 — neuroscience — Posted on 2020-01-09

3005 Convergent evolution of seasonal camouflage in response to reduced snow cover across the snowshoe hare range

Jones, M.; Mills, L. S.; Jensen, J. D.; Good, J. M.

10.1101/851766 — evolutionary biology — Posted on 2020-01-09

3006 GLP-1 Notch - LAG-1 CSL control of the germline stem cell fate is mediated by transcriptional targets lst-1 and sygl-1

Schedl, T.; Chen, J.; Mohammad, A.; Pazdernik, N.; Huang, H.; Bowman, B.; Tycksen, E.

10.1101/825232 — developmental biology — Posted on 2020-01-09

3007 A Sparse Additive Model for High-Dimensional Interactions with an Exposure Variable

Bhatnagar, S. R.; Lu, T.; Lovato, A.; Olds, D. L.; Kobor, M. S.; Meaney, M. J.; O'Donnell, K.; Yang, Y.; Greenwood, C. M.

10.1101/445304 — bioinformatics — Posted on 2020-01-09

3008 Interpretable multimodal deep learning for real-time pan-tissue pan-disease pathology search on social media

Schaumberg, A. J.; Juarez, W.; Choudhury, S. J.; Pastrian, L. G.; Pritt, B. S.; Prieto Pozuelo, M.; Sotillo Sanchez, R.; Ho, K.; Zahra, N.; Sener, B. D.; Yip, S.; Xu, B.; Annavarapu, S. R.; Morini, A.; Jones, K. A.; Rosado-Orozco, K.; Mukhopadhyay, S.; Miguel, C.; Yang, H.; Rosen, Y.; Ali, R. H.; Folaranmi, O. O.; Gardner, J. M.; Suleiman, D. E.; Rusu, C.; Stayerman, C.; Gross, J.; Sirintrapun, S. J.; Aly, M.; Fuchs, T. J.

10.1101/396663 — pathology — Posted on 2020-01-09

3009 Reconfigurations within resonating communities of brain regions following TMS reveal different scales of processing

Garcia, J. O.; Ashourvan, A.; Thurman, S. M.; Srinivasan, R.; Bassett, D. S.; Vettel, J. M.

10.1101/500967 — neuroscience — Posted on 2020-01-09

3010 Enlarging the Scope of Randomization and Permutation Tests in Neuroimaging and Neuroscience

Maris, E.

10.1101/685560 — neuroscience — Posted on 2020-01-09

3011 Marked Neurospora crassa strains for competition experiments and Bayesian methods for fitness estimates

Kronholm, I.; Ormsby, T.; McNaught, K. J.; Selker, E. U.; Ketola, T.

10.1101/736645 — genetics — Posted on 2020-01-09

3012 The source of additive genetic variance of evolutionarily important traits

Liu, L.; Wang, Y.; Zhang, D.; Chen, X.; Su, Z.; He, X.

10.1101/776898 — evolutionary biology — Posted on 2020-01-09

3013 Differential antitumor activity of compounds targeting the ubiquitin-proteasome machinery in gastrointestinal stromal tumor (GIST) cells

Rausch, J. L.; Ali, A. A.; Lee, D. M.; Gebreyohannes, Y. K.; Mehalek, K. R.; Agha, A.; Patil, S. S.; Tolstov, Y.; Wellens, J.; Dhillon, H. S.; Makielski, K. R.; Debiec-Rychter, M.; Schoeffski, P.; Wozniak, A.; Duensing, A.

10.1101/791426 — cancer biology — Posted on 2020-01-09

3014 MetaLab 2.0 enables accurate post-translational modifications profiling in metaproteomics

Cheng, K.; Ning, Z.; Zhang, X.; Li, L.; Liao, B.; Mayne, J.; Figeys, D.

10.1101/753996 — bioinformatics — Posted on 2020-01-09

3015 Recording from the same neuron with high-density CMOS probes and patch-clamp: a ground-truth dataset and an experiment in collaboration.

Marques-Smith, A.; Neto, J. P.; Lopes, G.; Nogueira, J.; Calcaterra, L.; Frazao, J.; Kim, D.; Phillips, M. G.; Dimitriadis, G.; Kampff, A.

10.1101/370080 — neuroscience — Posted on 2020-01-09

3016 Automation of citation screening in pre-clinical systematic reviews

Liao, J.; Ananiadou, S.; Currie, G. L.; Howard, B. E.; Rice, A.; Sena, E. S.; Thomas, J.; Varghese, A.; Macleod, M. R.

10.1101/280131 — neuroscience — Posted on 2020-01-09

3017 Flexible neural connectivity under constraints on total connection strength

Ocker, G. K.; Buice, M. A.

10.1101/603027 — neuroscience — Posted on 2020-01-09

3018 In vivo control of the ezrin/radixin/moesin protein ERM-1 in C. elegans

Ramalho, J. J.; Nicolle, O.; Michaux, G.; Boxem, M.

10.1101/2020.01.08.898189 — cell biology — Posted on 2020-01-08

3019 HDAC inhibitor Givinostat targets DNA-binding of human CGGBP1

Patel, M.; Patel, D.; Datta, S.; Singh, U.

10.1101/2020.01.08.898494 — cancer biology — Posted on 2020-01-08

3020 Transcriptional elongation machinery controls vulnerability of breast cancer cells to PRC2 inhibitors

Xu, W.; Chan, N. T.; Liu, P.; Huang, J.; Wang, Y.; Ong, I. M.; Li, L.

10.1101/2020.01.08.898577 — cancer biology — Posted on 2020-01-08

3021 Evaluation of a pan-Leishmania SL-RNA qPCR assay for parasite detection in laboratory-reared and field-collected sand flies and reservoir hosts.

Pareyn, M.; Hendrickx, R.; Girma, N.; Hendrickx, S.; Van Bockstal, L.; Van Houtte, N.; Shibru, S.; Maes, L.; Leirs, H.; Caljon, G.

10.1101/2020.01.08.898411 — microbiology — Posted on 2020-01-08

3022 NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis

Tourniere, O.; Dolan, D.; Richards, G. S.; Sunagar, K.; Columbus-Shenkar, Y. Y.; Moran, Y.; Rentzsch, F.

10.1101/2020.01.08.898437 — developmental biology — Posted on 2020-01-08

3023 A Rainbow Reporter Tracks Single Cells and Reveals Heterogeneous Cellular Dynamics among Pluripotent Stem Cells and their Differentiated Derivatives

El-Nachef, D.; Shi, K.; Beussman, K. M.; Martinez, R.; Regier, M. C.; Everett, G. W.; Murry, C. E.; Stevens, K. R.; Young, J. E.; Sniadecki, N. J.; Davis, J.

10.1101/2020.01.08.896290 — cell biology — Posted on 2020-01-08

3024 Mitochondrial fission factor (MFF) is a critical regulator of peroxisome maturation

Passmore, J. B.; Godinho, L. F.; Ferdinandusse, S.; Lismont, C.; Wang, Y.; Hacker, C.; Islinger, M.; Fransen, M.; Richards, D. M.; Freisinger, P.; Schrader, M.

10.1101/2020.01.08.898486 — cell biology — Posted on 2020-01-08

3025 Convergent Met and voltage-gated Ca2+ channel signaling on Ras-Erk MAPK drives migratory activation of dendritic cells parasitized by Toxoplasma gondii

Olafsson, E. B.; ten Hoeve, A. L.; Li Wang, X.; Westermark, L.; Varas-Godoy, M.; Barragan, A.

10.1101/2020.01.08.898197 — cell biology — Posted on 2020-01-08

3026 In depth analysis of kinase cross screening data to identify CAMKK2 inhibitory scaffolds

O'Byrne, S.; Scott, J. W.; Pilotte, J. R.; Santiago, A. d. S.; Langendorf, C. G.; Oakhill, J. S.; Eduful, B. J.; Counago, R. M.; Wells, C. I.; Zuercher, W.; Willson, T.; Drewry, D. H.

10.1101/2020.01.08.883009 — cancer biology — Posted on 2020-01-08

3027 A silent disco: Persistent entrainment of low-frequency neural oscillations underlies beat-based, but not memory-based temporal expectations

Bouwer, F. L.; Fahrenfort, J. J.; Millard, S. K.; Slagter, H. A.

10.1101/2020.01.08.899278 — neuroscience — Posted on 2020-01-08

3028 Abdominal symptoms during primary Sjögren's syndrome: a prospective study

Parreau, S.; Jacques, J.; Dumonteil, S.; Palat, S.; Geyl, S.; Gondran, G.; Bezanahary, H.; Liozon, E.; Azaïs, J.; Colombie, S.; Jauberteau, M.-O.; Loustaud-Ratti, V.; Ly, K.-H.; Fauchais, A.-L.

10.1101/2020.01.08.898379 — immunology — Posted on 2020-01-08

3029 Loss of Complement Factor H impairs antioxidant capacity and energy metabolism of human RPE cells

Armento, A.; Honisch, S.; Panagiotakopoulou, V.; Sonntag, I.; Jacob, A.; Kilger, E.; Deleidi, M.; Clark, S. J.; Ueffing, M.

10.1101/2020.01.08.898551 — cell biology — Posted on 2020-01-08

3030 Cell autonomous versus systemic Akt isoform deletions uncovered new roles for Akt1 and Akt2 in breast cancer

Hay, N.; Chen, X.; Ariss, M. M.; Ramakrishnan, G.; Nogueira, V.; Blaha, C.; Putzbach, W.; Islam, A. B. M. M. K.; Frolov, M. V.

10.1101/2020.01.08.898767 — cancer biology — Posted on 2020-01-08

3031 4DNvestigator: a toolbox for the analysis of time series Hi-C and RNA-seq data

Rajapakse, I.; Ronquist, S.; Perlman, M.; Lu, S.

10.1101/2020.01.08.898387 — bioinformatics — Posted on 2020-01-08

3032 Taxonomic classification method for metagenomics based on core protein families with Core-Kaiju

Tovo, A.; Suweis, S.; Menzel, P.; Krogh, A.; Cosentino Lagomarsino, M.

10.1101/2020.01.08.898395 — bioinformatics — Posted on 2020-01-08

3033 Zika and dengue but not chikungunya are associated with Guillain-Barre syndrome in Mexico: a case-control study

Grijalva, I.; Grajales-Muniz, C.; Gonzalez-Bonilla, C.; Borja-Aburto, V. H.; Paredes-Cruz, M.; Guerrero-Cantera, J.; Gonzalez-Ibarra, J.; Vallejos-Paras, A.; Rojas-Mendoza, T.; Santacruz-Tinoco, C. E.; Hernandez-Bautista, P.; Arriaga-Nieto, L.; Garza-Sagastegui, M.; Vargas-Ramos, I.; Sepulveda-Nunez, A.; Campos-Villarreal, O. I.; Corrales-Perez, R.; Azuara-Castillo, M.; Sierra-Gonzalez, E.; Meza-Medina, J. A.; Martinez-Miguel, B.; Lopez-Becerril, G.; Ramos-Orozco, J.; Munoz-Guerrero, T.; Gutierrez-Lozano, M. S.; Cervantes-Ocampo, A. A.

10.1101/2020.01.08.898403 — microbiology — Posted on 2020-01-08

3034 Brain-wide mapping of water flow perception in zebrafish

Vanwalleghem, G. C.; Schuster, K.; Taylor, M. A.; Favre-Bulle, I. A.; Scott, E. K.

10.1101/2020.01.07.896738 — neuroscience — Posted on 2020-01-08

3035 Work horse strain Clostridioides difficile 630Δerm is oblivious to its anaerobic lifestyle

Troitzsch, D.; Zhang, H.; Dittmann, S.; Düsterhöft, D.; Michel, A.-M.; Jänsch, L.; Riedel, K.; Borrero-de Acuna, J. M.; Jahn, D.; Sievers, S.

10.1101/2020.01.07.897181 — microbiology — Posted on 2020-01-08

3036 Macroevolutionary analysis of discrete traits with rate heterogeneity

Grundler, M.; Rabosky, D. L.

10.1101/2020.01.07.897777 — evolutionary biology — Posted on 2020-01-08

3037 ALPPL2 is a highly specific and targetable tumor cell surface antigen

Su, Y.; Zhang, X.; Bidlingmaier, S.; Behrens, C. R.; Lee, N.-K.; Liu, B.

10.1101/2020.01.07.898122 — cancer biology — Posted on 2020-01-08

3038 Survey of metaproteomics software tools for functional microbiome analysis.

10.1101/2020.01.07.897561 — bioinformatics — Posted on 2020-01-08

3039 Reconstruction of Gene Regulatory Networks by integrating biological model and a recommendation system

Wang, Y.; Fear, J.; Berger, I.; Lee, H.; Oliver, B.; Przytycka, T. M.

10.1101/2020.01.07.898031 — bioinformatics — Posted on 2020-01-08

3040 Information theory tests critical predictions of plant defense theory for specialized metabolism

Li, D.; Halitschke, R.; Baldwin, I. T.; Gaquerel, E.

10.1101/2020.01.07.897389 — plant biology — Posted on 2020-01-08

3041 cAMP-Fyn signaling in the dorsomedial striatum direct pathway drives excessive alcohol use

Ehinger, Y.; Morisot, N.; Sakhai, S.; Phamluong, K.; Adrover, M.; Alvarez, V.; Ron, D.

10.1101/2020.01.07.898023 — neuroscience — Posted on 2020-01-08

3042 A subpopulation of spinocerebellar tract neurons regulates the stability of bipedal stepping

Haimson, B.; Hadas, Y.; Kania, A.; A, M.; Cinnamon, Y.; Lev-Tov, A.; Klar, A.

10.1101/2020.01.07.898072 — neuroscience — Posted on 2020-01-08

3043 Constructing plasticity phenotypes to classify experience-dependent development of the visual cortex

Balsor, J.; Jones, D. G.; Murphy, K. M.

10.1101/2020.01.07.896191 — neuroscience — Posted on 2020-01-08

3044 Decoding the regulatory architecture of the maize leaf

Tu, X.; Mejia Guerra, M. K.; Franco, J. A. V.; Tzeng, D.; Chu, P.-Y.; Dai, X.; Li, P.; Buckler, E. S.; Zhong, S.

10.1101/2020.01.07.898056 — molecular biology — Posted on 2020-01-08

3045 Role of DNA Methylation in Persister Formation in Uropathogenic E. coli

Xu, Y.; Liu, S.; Zhang, W.; Zhang, Y.

10.1101/2020.01.07.897686 — microbiology — Posted on 2020-01-08

3046 Genomic surveillance enables suitability assessment of Salmonella gene targets used for culture-independent diagnostic testing

Rockett, R. J.; Arnott, A.; Wang, Q.; Howard, P.; Sintchenko, V.

10.1101/2020.01.07.898015 — microbiology — Posted on 2020-01-08

3047 siRNA-mediated de novo silencing of Ac/Ds transposons is initiated by alternative transposition in maize

Wang, D.; Zhang, J.; Zuo, T.; Lisch, D.; Zhao, M.; Peterson, T.

10.1101/2020.01.07.897926 — genetics — Posted on 2020-01-08

3048 Mono-ADP-ribosylation by ARTD10 restricts Chikungunya virus replication by interfering with the proteolytic activity of nsP2

Krieg, S.; Pott, F.; Eckei, L.; Verheirstaeten, M.; Buetepage, M.; Lippok, B.; Goffinet, C.; Luescher, B.; Verheugd, P.

10.1101/2020.01.07.896977 — microbiology — Posted on 2020-01-08

3049 SparkINFERNO: A scalable high-throughput pipeline for inferring molecular mechanisms of non-coding genetic variants

Kuksa, P. P.; Lee, C.-Y.; Amlie-Wolf, A.; Gangadharan, P.; Mlynarski, E. E.; Chou, Y.-F.; Lin, H.-J.; Issen, H.; Greenfest-Allen, E.; Valladares, O.; Leung, Y. Y.; Wang, L.-S.

10.1101/2020.01.07.897579 — bioinformatics — Posted on 2020-01-08

3050 The wild grape genome sequence provides insights into the transition from dioecy to hermaphroditism during grape domestication

10.1101/2020.01.07.897082 — plant biology — Posted on 2020-01-08

3051 Sharp-wave ripples in human amygdala and their coordination with hippocampus

Cox, R.; Ruber, T.; Staresina, B.; Fell, J.

10.1101/2020.01.07.897413 — neuroscience — Posted on 2020-01-08

3052 Inhibitory regulation of calcium transients in prefrontal dendritic spines is compromised by a nonsense Shank3 mutation

Ali, F.; Shao, L.-X.; Gerhard, D. M.; Sweasy, K.; Pothula, S.; Pittenger, C.; Duman, R. S.; Kwan, A. C.

10.1101/2020.01.07.894832 — neuroscience — Posted on 2020-01-08

3053 A validation framework for neuroimagingsoftware: the case of populationreceptive fields

Lerma-Usabiaga, G.; Benson, N.; Winawer, J.; Wandell, B. A.

10.1101/2020.01.07.897991 — neuroscience — Posted on 2020-01-08

3054 ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration

Aharonov, A.; Shakked, A.; Umansky, K. B.; Savidor, A.; Kain, D.; Lendengolts, D.; Revach, O.-Y.; Morikawa, Y.; Dong, J.; Levin, Y.; Geiger, B.; Martin, J. F.; Tzahor, E.

10.1101/2020.01.07.897199 — molecular biology — Posted on 2020-01-08

3055 RNA-binding protein Syncrip regulates Starvation-Induced Hyperactivity in adult Drosophila

Chi, W.; Liu, W.; Fu, W.; Heckscher, E.; Zhuang, X.

10.1101/2020.01.07.897652 — genomics — Posted on 2020-01-08

3056 The copy-number and varied strengths of MELT motifs in Spc105 balance the strength and responsiveness the Spindle Assembly Checkpoint

Roy, B.; Joglekar, A.; Fontan, A. N.; Han, S. J. Y.

10.1101/2020.01.07.897876 — cell biology — Posted on 2020-01-08

3057 Human papillomavirus 16 positive cervical cancer in Guatemala: The D2 and D3 sublineages differ in integration rate and age of diagnosis

Lou, H.; Boland, J. F.; Torres-Gonzalez, E.; Albanez, A.; Zhou, W.; Steinberg, M.; Diaw, L.; Mitchell, J.; Roberson, D.; Cullen, M.; Garland, L.; Bass, S.; Burk, R.; Yeager, M.; Wentzensen, N.; Schiffman, M.; Alvirez, E.; Gharzouzi, E.; Mirabello, L.; Dean, M.

10.1101/2020.01.07.897546 — cancer biology — Posted on 2020-01-08

3058 Basal-like and Classical cells coexistence in pancreatic cancer revealed by single cell analysis

Dusetti, N. J.; Juiz, N.; Elkaoutari, A.; Bigonnet, M.; Gayet, O.; Roques, J.; Nicolle, R.; Iovanna, J. L.

10.1101/2020.01.07.897454 — cancer biology — Posted on 2020-01-08

3059 Post-transcriptional Regulation is the Major Driver of microRNA Expression Variation

Zhang, D.; Tian, J.; Roden, C.; Lu, J.

10.1101/2020.01.07.897975 — bioinformatics — Posted on 2020-01-08

3060 Receptor compaction and GTPase movements drive cotranslational protein translocation

Lee, J. H.; Chung, S.; Hwang Fu, Y.-H.; Qian, R.; Sun, X.; Weiss, S.; Shan, S.-o.

10.1101/2020.01.07.897827 — biochemistry — Posted on 2020-01-08

3061 Anomalous reverse transcription through chemical modifications in polyadenosine stretches

Kladwang, W.; Topkar, V. V.; Liu, B.; Hodges, T.; Keane, S.; Al-Hashimi, H.; Das, R.

10.1101/2020.01.07.897843 — biochemistry — Posted on 2020-01-08

3062 Low light levels increase avoidance behaviour of diurnal fish species: Implications for road culverts

Keep, J. K.; Watson, J. R.; Cramp, R. L.; Jones, M. J.; Gordos, M. A.; Franklin, C. E.

10.1101/2020.01.07.896605 — zoology — Posted on 2020-01-08

3063 Carbamazepine restores neuronal signaling, protein synthesis and cognitive function in a mouse model of fragile X syndrome

Ding, Q.; Zhang, F.; Feng, Y.; Wang, H.

10.1101/2020.01.07.897835 — neuroscience — Posted on 2020-01-08

3064 Effect of light and darkness on the growth and development of downy mildew pathogen Hyaloperonospora arabidopsidis.

Telli, O.; Jimenez-Quiros, C.; McDowell, J.; Tor, M.

10.1101/2020.01.07.897215 — microbiology — Posted on 2020-01-08

3065 Bayesian Inference of Cell Composition and Gene Expression Reveals Tumor-Microenvironment Interactions

Chu, T.; Danko, C. G.

10.1101/2020.01.07.897900 — genomics — Posted on 2020-01-08

3066 RECAS9: Recombining wild species introgression via mitotic gene editing in barley

Lazar, S.; Prusty, M. R.; Bishara, K.; Sherman, A.; Fridman, E.

10.1101/2020.01.07.897280 — genetics — Posted on 2020-01-08

3067 The Latent Genetic Structure of Impulsivity and its Relation to Internalizing Psychopathology

Gustavson, D. E.; Friedman, N. P.; Fontanillas, P.; Elson, S. L.; the 23andMe Research Team, ; Palmer, A. A.; Sanchez-Roige, S.

10.1101/2020.01.07.897231 — genetics — Posted on 2020-01-08

3068 Macroevolutionary analysis of discrete character evolution using parsimony-informed likelihood

Grundler, M.; Rabosky, D. L.

10.1101/2020.01.07.897603 — evolutionary biology — Posted on 2020-01-08

3069 Infestation dynamics between parasitic Antarctic fish leeches (Piscicolidae) and their crocodile icefish hosts (Channichthyidae)

Parker, E.; Jones, C.; Arana, P. M.; Alegria, N. A.; Sarralde, R.; Gallardo, F.; Phillips, A. J.; Williams, B. W.; Dornburg, A.

10.1101/2020.01.07.897496 — ecology — Posted on 2020-01-08

3070 Geminin is required for Hox gene regulation to pattern the developing limb

Lewis, E. M. A.; Sankar, S.; Tong, C.; Patterson, E.; Waller, L. E.; Gontarz, P.; Zhang, B.; Ornitz, D. M.; Kroll, K. L.

10.1101/2020.01.07.896472 — developmental biology — Posted on 2020-01-08

3071 Error correction enables use of Oxford Nanopore technology for reference-free transcriptome analysis

Sahlin, K.; Sipos, B.; James, P. L.; Turner, D. J.; Medvedev, P.

10.1101/2020.01.07.897512 — bioinformatics — Posted on 2020-01-08

3072 TLmutation: predicting the effects of mutations using transfer learning

Shamsi, Z.; Chan, M.; Shukla, D.

10.1101/2020.01.07.897892 — bioinformatics — Posted on 2020-01-08

3073 Development and validation of a potent and specific inhibitor provides evidence for the CLC-2 chloride channel as a potential epilepsy target

Du Bois, J.; Maduke, M.; Huguenard, J.

10.1101/2020.01.07.897785 — neuroscience — Posted on 2020-01-08

3074 Enhanced triacylglycerol (TAG) and protein accumulation in transgenic diatom Thalassiosira pseudonana with altered photosynthetic pigmentation

Gaidarenko, O.; Yee, D. P.; Hildebrand, M.

10.1101/2020.01.07.897850 — microbiology — Posted on 2020-01-08

3075 General DNA methylation patterns and environmentally-induced differential methylation in the eastern oyster (Crassostrea virginica)

Venkataraman, Y. R.; Downey-Wall, A.; Ries, J.; Westfield, I.; White, S. J.; Roberts, S.; Lotterhos, K. E.

10.1101/2020.01.07.897934 — genomics — Posted on 2020-01-08

3076 Silencing of TaCKX1 mediates expression of other TaCKX genes to increase grain yield in wheat

Jablonski, B.; Ogonowska, H.; Szala, K.; Bajguz, A.; Orczyk, W.; Nadolska-Orczyk, A.

10.1101/2020.01.07.897421 — genetics — Posted on 2020-01-08

3077 Novel genetic features of human and mouse Purkinje cell differentiation defined by comparative transcriptomics.

Buchholz, D. E.; Carroll, T. S.; Kocabas, A.; Zhu, X.; Behesti, H.; Faust, P. L.; Stalbow, L.; Fang, Y.; Hatten, M. E.

10.1101/2020.01.07.897371 — developmental biology — Posted on 2020-01-08

3078 Atomistic basis of microtubule dynamic instability assessed via multiscale modeling

Hemmat, M.; Odde, D. J.

10.1101/2020.01.07.897439 — biophysics — Posted on 2020-01-08

3079 Inhibition mechanism of human sterol O-acyltransferase 1 by competitive inhibitor

Guan, C.; Niu, Y.; Chen, S.-C.; Kang, Y.; Wu, J.-X.; Nishi, K.; Chang, C. C. Y.; Chang, T.-Y.; Luo, T.; Chen, L.

10.1101/2020.01.07.897124 — biochemistry — Posted on 2020-01-08

3080 Metacognition and memory of emotional information:Judgments of learning predict the affectivity congruence effect in free recall

Siedlecka, M.; Blaut, A.; Paulewicz, B.; Klosowska, J.

10.1101/2020.01.07.897165 — animal behavior and cognition — Posted on 2020-01-08

3081 Genome wide association study pinpoints key agronomic QTLs in African rice Oryza glaberrima

CUBRY, P.; Pidon, H.; Ta, K. N.; Tranchant-Dubreuil, C.; Thuillet, A.-C.; Holzinger, M.; Adam, H.; Kam, H.; Chrestin, H.; Ghesquiere, A.; Francois, O.; Sabot, F.; Vigouroux, Y.; Albar, L.; Jouannic, S.

10.1101/2020.01.07.897298 — plant biology — Posted on 2020-01-08

3082 Strigolactone defective mutants of Arabidopsis exhibit delayed sepal senescence

Xu, X.; Jibran, R.; Wang, Y.; Dong, L.; Flokova, K.; Esfandiari, A.; McLachlan, A.; Heiser, A.; Sutherland-Smith, A.; Bouwmeester, H. J.; Dijkwel, P.; Hunter, D. A.

10.1101/2020.01.07.897272 — plant biology — Posted on 2020-01-08

3083 Preliminary Evaluation of the Utility of Deep Generative Histopathology Image Translation at a Mid-Sized NCI Cancer Center

Levy, J. J.; Jackson, C. R.; Sriharan, A.; Christensen, B.; Vaickus, L. J.

10.1101/2020.01.07.897801 — pathology — Posted on 2020-01-08

3084 Identification and antimicrobial properties of bacteria isolated from naturally decaying wood

Scheublin, T. R.; Kielak, A. M.; van den Berg, M.; van Veen, J. A.; de Boer, W.

10.1101/2020.01.07.896464 — microbiology — Posted on 2020-01-08

3085 Unequal contribution of two paralogous centromeric histones to function the cowpea centromere

Ishii, T.; Juranic, M.; Maheshwari, S.; Bustamante, F.; Vogt, M.; Salinas-Gamboa, R.; Dreissig, S.; Gursanscky, N.; How, T.; Fuchs, J.; Schubert, V.; Spriggs, A.; Vielle Calzada, J. P.; Comai, L.; Koltunow, A.; Houben, A.

10.1101/2020.01.07.897074 — genetics — Posted on 2020-01-08

3086 Spatiotemporal Genetic Diversity of Lions

Curry, C. J.; Davis, B. W.; Bertola, L. D.; White, P. A.; Murphy, W. J.; Derr, J. N.

10.1101/2020.01.07.896431 — genetics — Posted on 2020-01-08

3087 Increased antibiotic susceptibility in Neisseria gonorrhoeae through adaptation to the cervical environment

Ma, K. C.; Mortimer, T. D.; Hicks, A. L.; Wheeler, N. E.; Sanchez-Buso, L.; Golparian, D.; Taiaroa, G.; Rubin, D. H.; Wang, Y.; Williamson, D. A.; Unemo, M.; Harris, S. R.; Grad, Y. H.

10.1101/2020.01.07.896696 — microbiology — Posted on 2020-01-08

3088 Role of Sulphate Transporter (PiSulT) of Endophytic Fungus Serendipita indica in Plant Growth and Development

Narayan, O. P.; Verma, N.; Jogawat, A.; Dua, M.; Johri, A. K.

10.1101/2020.01.07.897710 — microbiology — Posted on 2020-01-08

3089 A Framework of All Discovered Immunological Pathways and Their Roles for Four Specific Types of Pathogens and Hypersensitivities

Hu, W.

10.1101/006965 — immunology — Posted on 2020-01-08

3090 Diagnosis of Duchenne Muscular Dystrophy using Raman Hyperspectroscopy

Ralbovsky, N. M.; Dey, P.; Galfanoa, A.; Dey, B. K.; Lednev, I. K.

10.1101/2020.01.08.897793 — pathology — Posted on 2020-01-08

3091 MAIT cells are minimally responsive to Mycobacterium tuberculosis within granulomas, but are functionally impaired by SIV in a macaque model of SIV and Mtb co-infection

Ellis, A. L.; Balgeman, A. J.; Larson, E. C.; Rodgers, M.; Ameel, C.; Baranowski, T.; Maiello, P.; Juno, J.; Scanga, C.; O'Connor, S. L.

10.1101/2020.01.07.897447 — immunology — Posted on 2020-01-08

3092 TCF-1 regulates the stem-like memory potential of HIV-specific CD8+ T cells in elite controllers

Rutishauser, R. L.; Deguit, C. D. T.; Hiatt, J.; Blaeschke, F.; Roth, T. L.; Wang, L.; Raymond, K.; Starke, C. E.; Mudd, J. C.; Chen, W.; Smullin, C.; Matus-Nicodemos, R.; Hoh, R.; Krone, M.; Hecht, F. M.; Pilcher, C. D.; Martin, J. N.; Koup, R. A.; Douek, D. C.; Brenchley, J. M.; Sekaly, R.-P.; Pillai, S. K.; Marson, A.; Deeks, S. G.; McCune, J. M.; Hunt, P. W.

10.1101/2020.01.07.894535 — immunology — Posted on 2020-01-08

3093 RIP1 kinase activity promotes steatohepatitis through mediating cell death and inflammation in macrophages

Tao, L.; Yi, Y.; Chen, Y.; Zhang, H.; Jie, J.; Zhang, W.; Xu, Q.; Li, Y.; Orning, P.; Lien, E.; Zhao, M.; Gao, P.; Ling, L.; Ding, Z.; Wu, C.; Ding, Q.; Wang, J.; Zhang, J.; Weng, D.

10.1101/2020.01.07.895516 — immunology — Posted on 2020-01-08

3094 Identifying novel B-cell targets for chronic inflammatory autoimmune disease by screening of chemical probes in a patient-derived cell assay

Sundstrom, Y.; Shang, M.-M.; Panda, S. K.; Gronwall, C.; Wermeling, F.; Gunnarsson, I.; Lundberg, I. E.; Sundstrom, M.; Jakobsson, P.-J.; Berg, L.

10.1101/2020.01.08.898270 — immunology — Posted on 2020-01-08

3095 Phylogenomics supported by geometric morphometrics reveals delimitation of sexual species within the polyploid apomictic Ranunculus auricomus complex (Ranunculaceae)

Karbstein, K.; Tomasello, S.; Hodac, L.; Dunkel, F.; Daubert, M.; Hoerandl, E.

10.1101/2020.01.07.896902 — evolutionary biology — Posted on 2020-01-08

3096 Lysine Acetylation Reshapes The Downstream Signaling Landscape Of Vav1 In Lymphocytes

Rodriguez-Fdez, S.; Nevado, L. F.; Lorenzo-Martin, L. F.; Bustelo, X. R.

10.1101/2020.01.07.897017 — biochemistry — Posted on 2020-01-08

3097 Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early genes.

Lee, C.-H.; Chiweshe, S.; McCormick, D.; Raper, A. R.; wickenhagen, A.; DeFilippis, V. R.; GAUNT, E.; Simmonds, P.; Wilson, S. J.; Grey, F.

10.1101/2020.01.07.897132 — microbiology — Posted on 2020-01-08

3098 Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons

Ji, D. X.; Witt, K. C.; Kotov, D. I.; Margolis, S. R.; Louie, A.; Chen, K. J.; Dhaliwal, H. S.; Lee, A. Y.; Zamboni, D. S.; Kramnik, I.; Portnoy, D. A.; Darwin, K. H.; Vance, R. E.

10.1101/2020.01.07.897553 — immunology — Posted on 2020-01-08

3099 Representation of k-mer sets using spectrum-preserving string sets

Rahman, A.; Medvedev, P.

10.1101/2020.01.07.896928 — bioinformatics — Posted on 2020-01-08

Beaudet, G.; Tsuchida, A.; Petit, L.; Tzourio, C.; Caspers, S.; Schreiber, J.; Pausova, Z.; Patel, Y.; Paus, T.; Schmidt, R.; Pirpamer, L.; Sachdev, P. S.; Brodathy, H.; Kochan, N.; Trollor, J.; Wen, W.; Armstrong, N.; Deary, I. J.; Bastin, M. E.; Warlaw, J. M.; Maniega, S. M.; Witte, V. A.; Villringer, A.; During, M.; Stephanie, D.; Mazoyer, B.

10.1101/2020.01.07.896951 — neuroscience — Posted on 2020-01-08

3101 Detection of phylogenetic core groups in diverse microbial ecosystems

Aguirre de Carcer, D.; Parras-Molto, M.

10.1101/2020.01.07.896985 — microbiology — Posted on 2020-01-08

3102 Targeting a critical step in fungal hexosamine biosynthesis

Lockhart, D. E. A.; Stanley, M.; Raimi, O. G.; Robinson, D. A.; Boldovjakova, D.; Squair, D. R.; Ferenbach, A. T.; Fang, W.; van Aalten, D. M. F.

10.1101/2020.01.07.896944 — microbiology — Posted on 2020-01-08

3103 Ecological assembly processes of the bacterial and fungal microbiota of wild and domesticated wheat species

Hassani, M. A.; Özkurt, E.; Franzenburg, S.; Stukenbrock, E. H.

10.1101/2020.01.07.896910 — microbiology — Posted on 2020-01-08

3104 MAnorm2 for quantitatively comparing groups of ChIP-seq samples

Tu, S.; Li, M.; Tan, F.; Chen, H.; Xu, J.; Waxman, D. J.; Zhang, Y.; Shao, Z.

10.1101/2020.01.07.896894 — bioinformatics — Posted on 2020-01-08

3105 Hydrogen evolution and absorption phenomena in plasma membrane of higher plants

Zhang, X.; Zhang, Z.; Su, Z.; Zhao, Q.; LeBaron, T. W.; Li, Q.; Lyu, B.; Adzavon, Y. M.; Liu, G.; Liu, M.; Xie, F.; Zhao, P.; Ma, X.

10.1101/2020.01.07.896852 — biochemistry — Posted on 2020-01-08

3106 Perceptual decisions are biased toward relevant prior choices

Feigin, H.; Baror, S.; Bar, M.; Zaidel, A.

10.1101/858324 — neuroscience — Posted on 2020-01-08

3107 Molecular Evolution of the Sex Peptide Network in Drosophila

McGeary, M. K.; Findlay, G. D.

10.1101/833939 — evolutionary biology — Posted on 2020-01-08

3108 Single cell epigenomic atlas of the developing human brain and organoids

Ziffra, R. S.; Kim, C. N.; Wilfert, A.; Turner, T. N.; Haeussler, M.; Casella, A. M.; Przytycki, P. F.; Kreimer, A.; Pollard, K. S.; Ament, S. A.; Eichler, E. E.; Ahituv, N.; Nowakowski, T. J.

10.1101/2019.12.30.891549 — developmental biology — Posted on 2020-01-08

3109 Phoenix Enhancer: proteomics data mining using clustered spectra

Bai, M.; Qin, C.; Shu, K.; Griss, J.; Perez-Riverol, Y.; Zhu, W.; Hermjakob, H.

10.1101/846303 — bioinformatics — Posted on 2020-01-08

3110 GmSALT3 confers shoot Na+ and Cl- exclusion in soybean via two distinct processes.

Qu, Y.; Guan, R.; Bose, J.; Henderson, S. W.; Wege, S.; Qiu, L.-J.; Gilliham, M.

10.1101/2020.01.06.896456 — plant biology — Posted on 2020-01-08

3111 Understanding visual attention with RAGNAROC: A Reflexive Attention Gradient through Neural AttRactOr Competition

Wyble, B.; Callahan-Flintoft, C.; Chen, H.; Marinov, T.; Sarkar, A.; Bowman, H.

10.1101/406124 — neuroscience — Posted on 2020-01-08

3112 Inference and visualization of phenome-wide causal relationships using genetic data: an application to dental caries and periodontitis.

Haworth, S.; Kho, P. F.; Holgerson, P. L.; Hwang, L.-D.; Timpson, N. J.; Renteria, M. E.; Johansson, I.; Cuellar Partida, G.

10.1101/865956 — genetics — Posted on 2020-01-08

3113 Genome-wide changes in genetic diversity in a population of Myotis lucifugus affected by white-nose syndrome

Lilley, T.; Wilson, I.; Field, K. A.; Reeder, D. M.; Vodzak, M. E.; Turner, G. G.; Kurta, A.; Blomberg, A. S.; Hoff, S.; Herzog, C.; Paterson, S.

10.1101/764647 — evolutionary biology — Posted on 2020-01-08

3114 The Somatic Golgi nucleates microtubules that are directed by Kinesin-2 to maintain microtubule polarity within neurons

Mukherjee, A.; Brooks, P.; Bernard, F.; Guichet, A.; Conduit, P. T.

10.1101/846832 — cell biology — Posted on 2020-01-08

3115 Identifying strategies to target the metabolic flexibility of tumours.

Mendez-Lucas, A.; Lin, W.; Driscoll, P. C.; Legrave, N.; Novellasdemunt Vilaseca, L.; Xie, C.; Charles, M.; Wilson, Z.; Jones, N. P.; Rayport, S. G.; Rodriguez-Justo, M.; Li, V. S. W.; MacRae, J. I.; Hay, N.; Chen, X.; Yuneva, M.

10.1101/2020.01.06.896571 — cancer biology — Posted on 2020-01-08

3116 ZEAMAP, a comprehensive database adapted to the maize multi-omics era

Gui, S.; Yang, L.; Li, J.; Luo, J.; Xu, X.; Yuan, J.; Chen, L.; Li, W.; Yang, X.; Wu, S.; Li, S.; Wang, Y.; Zhu, Y.; Gao, Q.; Yang, N.; Yan, J.

10.1101/2020.01.04.894626 — bioinformatics — Posted on 2020-01-08

3117 A possible coding for experience: ripple-like events and synaptic diversity

Ishikawa, J.; Tomokage, T.; Mitsushima, D.

10.1101/2019.12.30.891259 — animal behavior and cognition — Posted on 2020-01-08

3118 Dissociation between Frontal and Temporal-Parietal Contributions to Connected Speech in Acute Stroke

Ding, J.; Martin, R.; Hamilton, C.; Schnur, T. T.

10.1101/824300 — neuroscience — Posted on 2020-01-08

3119 Characterization of human-iPSCs derived spinal motor neurons by single-cell RNA sequencing

Thiry, L.; Hamel, R.; Pluchino, S.; Durcan, T.; Stifani, S.

10.1101/2019.12.28.889972 — neuroscience — Posted on 2020-01-08

3120 Predicting coexistence in experimental ecologicalcommunities

Maynard, D. S.; Miller, Z. R.; Allesina, S.

10.1101/598326 — ecology — Posted on 2020-01-08

3121 Cancer-Induced Immunosuppression can enable Effectiveness of Immunotherapy through Bistability Generation: a mathematical and computational Examination

Garcia, V.; Bonhoeffer, S.; Fu, F.

10.1101/498741 — cancer biology — Posted on 2020-01-08

3122 Crowdsourced mapping of unexplored target space of kinase inhibitors

Cichonska, A.; Ravikumar, B.; Allaway, R. J.; Park, S.; Wan, F.; Isayev, O.; Li, S.; Mason, M. J.; Lamb, A.; Tanoli, Z.-u.-R.; Jeon, M.; Kim, S.; Popova, M.; Capuzzi, S.; Zeng, J.; Dang, K.; Koytiger, G.; Kang, J.; Wells, C. I.; Willson, T. M.; The IDG-DREAM Drug-Kinase Binding Prediction Challenge Consortium, ; Oprea, T. I.; Schlessinger, A.; Drewry, D. H.; Stolovitzky, G. A.; Wennerberg, K.; Guinney, J.; Aittokallio, T.

10.1101/2019.12.31.891812 — biochemistry — Posted on 2020-01-08

3123 Genomic signature of accelerated evolution in a saline-alkaline lake-dwelling Schizothoracine fish

Tong, C.; Li, M.

10.1101/825885 — genomics — Posted on 2020-01-08

3124 Reduction of insulin/IGF-1 receptor rejuvenates immunity via positive feedback circuit

Lee, Y.; Jeong, D.-E.; Hwang, W.; Ham, S.; Park, H.-E.; Kwon, S.; Jung, Y.; Ashraf, J. M.; Murphy, C.; Lee, S.-J. V.

10.1101/795781 — genetics — Posted on 2020-01-08

3125 CTDSP1 inhibitor rabeprazole regulates DNA-PKcs dependent topoisomerase I degradation and irinotecan drug resistance in colorectal cancer

Matsuoka, H.; Ando, K.; Swayze, E. J.; Unan, E. C.; Mathew, J.; Hu, Q.; Tsuda, Y.; Nakashima, Y.; Saeki, H.; Oki, E.; Bharti, A. K.; Mori, M.

10.1101/2020.01.07.897355 — cancer biology — Posted on 2020-01-07

3126 Identification of QTLs for high grain yield and component traits in New Plant Types of rice

Donde, R.; Mohapatra, S.; Baksh, S. Y.; Padhy, B.; Mukherjee, M.; Roy, S.; Chattopadhyay, K.; Annamalai, A.; Swain, P.; Sahoo, K. K.; Singh, O. N.; Behera, L.; Dash, S. K.

10.1101/2020.01.07.897330 — plant biology — Posted on 2020-01-07

3127 Computed tomography reveals hip dysplasia in Smilodon: Implications for social behavior in an extinct Pleistocene predator

Balisi, M.; Sharma, A. K.; Howard, C. M.; Shaw, C. A.; Klapper, R.; Lindsey, E. L.

10.1101/2020.01.07.897348 — paleontology — Posted on 2020-01-07

3128 Early life adversity decreases fear expression in pre-adolescence by accelerating amygdalar parvalbumin cell development

Manzano Nieves, G.; Bravo, M.; Bath, K. G.

10.1101/2020.01.07.892687 — animal behavior and cognition — Posted on 2020-01-07

3129 Effective psychological treatment for PTSD changes the dynamics of specific large-scale brain networks

Charquero-Ballester, M.; Kleim, B.; Vidaurre, D.; Ruff, C.; Stark, E.; Tuulari, J. J.; McManners, H.; Bar-Haim, Y.; Bouquillon, L.; Moseley, A.; Williams, S. C. R.; Woolrich, M. W.; Kringelbach, M. L.; Ehlers, A.

10.1101/2020.01.07.891986 — neuroscience — Posted on 2020-01-07

3130 Voice and Face Gender Perception engages multimodal integration via multiple feedback pathways.

Abbatecola, C.; Beneyton, K.; Gerardin, P.; Kennedy, H.; Knoblauch, K.

10.1101/2020.01.07.884668 — neuroscience — Posted on 2020-01-07

3131 Structure-function relation of the developing calyx of Held synapse in vivo

Sierksma, M. C.; Slotman, J.; Houtsmuller, A. C.; Borst, J. G. G.

10.1101/2020.01.07.893685 — neuroscience — Posted on 2020-01-07

3132 GTO: a toolkit to unify pipelines in genomic and proteomic research

Almeida, J. R.; Pinho, A. J.; Oliveira, J. L.; Fajarda, O.; Pratas, D.

10.1101/2020.01.07.882845 — bioinformatics — Posted on 2020-01-07

3133 Nephrotic Syndrome-Associated Hypercoagulopathy is Alleviated by Nuclear Receptor Agonist Therapy with both Pioglitazone and Glucocorticoids

Waller, A. P.; Agrawal, S.; Wolfgang, K. J.; Kino, J.; Chanley, M. A.; Smoyer, W. E.; Kerlin, B. A.; Pediatric Nephrology Research Consortium (PNRC),

10.1101/2020.01.07.897751 — pathology — Posted on 2020-01-07

3134 Dose-Dependent Induction Of CPP Or CPA By Intra-pVTA Ethanol: Role Of Mu Opioid Receptors And Effects On NMDA Receptors

Campos-Jurado, Y.; Marti-Prats, L.; Moron, J. A.; Polache, A.; Granero, L.; Hipolito, L.

10.1101/2020.01.07.897702 — neuroscience — Posted on 2020-01-07

3135 Environmental DNA consistently outperforms established methods for detection of quagga mussels, Dreissena rostriformis bugensis in flowing water.

Blackman, R. C.; Ling, K. K. S.; Harper, L.; Shum, P.; Haenfling, B.; Lawson-Handley, L.

10.1101/2020.01.07.890731 — molecular biology — Posted on 2020-01-07

3136 Linking coleopteran diversity with agricultural management of maize agroecosystems in Oaxaca, Mexico

Gonzalez Gonzalez, C.; Lara Garcia, T.; Jardon-Barbolla, L. O.; Benitez, M.

10.1101/2020.01.07.897744 — ecology — Posted on 2020-01-07

3137 Social environment drives sex and age-specific variation in Drosophila melanogaster microbiome composition and predicted function.

Leech, T.; McDowall, L.; Hopkins, K. P.; Sait, S. M.; Harrison, X. A.; Bretman, A.

10.1101/2020.01.07.895631 — ecology — Posted on 2020-01-07

3138 Local retinoic acid directs emergence of the extraocular muscle functional unit

10.1101/2020.01.07.897694 — developmental biology — Posted on 2020-01-07

3139 Low-density Lipoprotein Receptor-related Protein 5 (LRP5)-deficient Rats Have Reduced Bone Mass and Abnormal Development of the Retinal Vasculature

Ubels, J. L.; Diegel, C. R.; Foxa, G. E.; Ethen, N. J.; Lensing, J. N.; Madaj, Z. B.; VARI Vivarium and Transgenics Core, ; Williams, B. O.

10.1101/2020.01.06.895797 — developmental biology — Posted on 2020-01-07

3140 The influence of relationship closeness on default-mode network connectivity during social interactions

Fareri, D. S.; Smith, D. V.; Delgado, M. R.

10.1101/815274 — neuroscience — Posted on 2020-01-07

3141 A systems-biology approach to molecular machines: Exploration of alternative transporter mechanisms

George, A.; Bisignano, P.; Rosenberg, J.; Grabe, M.; Zuckerman, D. M.

10.1101/685933 — biophysics — Posted on 2020-01-07

3142 DNA Punch Cards: Storing Data on Native DNA Sequences via Nicking

Tabatabaei, S. K.; Wang, B.; Athreya, N. B. M.; Enghiad, B.; Hernandez, A. G.; Leburton, J.-P.; Soloveichik, D.; Zhao, H.; Milenkovic, O.; Fields, C.

10.1101/672394 — synthetic biology — Posted on 2020-01-07

3143 Loss of AUXIN RESPONSE FACTOR 4 function alters plant growth, stomatal functions and improves tomato tolerance to salinity and water deficit

Bouzroud, S.; Gasparini, K.; Hu, G.; Barbosa, M. A. M.; Rosa, B. L.; Fahr, M.; Bendaou, N.; Bouzayen, M.; Zsogon, A.; Smouni, A.; Zouine, M.

10.1101/756387 — plant biology — Posted on 2020-01-07

3144 Cortical temporal hierarchy is immature in middle childhood

Moraczewski, D.; Nketia, J.; Redcay, E.

10.1101/678326 — neuroscience — Posted on 2020-01-07

3145 Control of brain state transitions with light

Barbero-Castillo, A.; Riefolo, F.; Matera, C.; Caldas-Martinez, S.; Mateos-Aparicio, P.; Weinert, J. F.; Claro, E.; Sanchez-Vives, M. V.; Gorostiza, P.

10.1101/793927 — neuroscience — Posted on 2020-01-07

3146 Exceptional biostability of paranemic crossover (PX) DNA, crossover-dependent nuclease resistance, and implications for DNA nanotechnology

Chandrasekaran, A. R.; Vilcapoma, J.; Dey, P.; Wong-Deyrup, S. W.; Dey, B. K.; Halvorsen, K.

10.1101/801407 — bioengineering — Posted on 2020-01-07

3147 Studies of NH4+ and NO3- uptake ability of subalpine plants and resource-use strategy identified by their functional traits.

Legay, N.; Grassein, F.; Arnoldi, C.; Raphael, S.; Philippe, L.; Lavorel, S.; Clement, J.-C.

10.1101/372235 — ecology — Posted on 2020-01-07

3148 Spectral and lifetime fluorescence unmixing via deep learning

Smith, J. T.; Ochoa, M.; Yan, P.; Intes, X.

10.1101/745216 — bioengineering — Posted on 2020-01-07

3149 A complex view of GPCR signal transduction: Molecular dynamics of the histamine H3 membrane receptor

Herrera-Zuniga, L. D.; Moreno-Vargas, L. M.; Ballaud, L.; Correa-Basurto, J.; Prada-Gracia, D.; Pastre, D.; Curmi, P.; Arrang, J.-M.; Maroun, R. C.

10.1101/604793 — bioinformatics — Posted on 2020-01-07

3150 Recovery from transgenerational RNA silencing is driven by gene-specific homeostasis

Devanapally, S.; Raman, P.; Allgood, S.; Ettefa, F.; Diop, M.; Chey, M.; Lin, Y.; Cho, Y. E.; Yin, R.; Jose, A. M.

10.1101/148700 — genetics — Posted on 2020-01-07

3151 Adult mice lacking VIP SCN neurons retain circadian locomotor behavior but exhibit dampened daily glucocorticoid rhythms

Mazuski, C.; Chen, S. P.; Herzog, E. D.

10.1101/2020.01.07.897140 — neuroscience — Posted on 2020-01-07

3152 Thin layer immunoassay; an economical approach to diagnose Helicobacter pylori Infection in gastroduodenal ulcer disease patients of Pakistan; a comparative analysis

AZIZ, F.; taj, y.; kazmi, S. u.

10.1101/2020.01.05.895375 — microbiology — Posted on 2020-01-07

3153 Mimicry of dopamine 1 receptor signaling with Cell-Penetrating Peptides

Lorenzon, N.; Gestin, M.; Langel, U.

10.1101/2020.01.07.897470 — pharmacology and toxicology — Posted on 2020-01-07

3154 Receptors, circuits and neural dynamics for prediction

Mohanta, S.; Afrasiabi, M.; Casey, C.; Tanabe, S.; Redinbaugh, M. J.; Kambi, N. A.; Phillips, J. M.; Polyakov, D.; Filbey, W.; Austerweil, J. L.; Sanders, R. D.; Saalmann, Y. B.

10.1101/2020.01.06.896589 — neuroscience — Posted on 2020-01-07

3155 Crowdsourced mapping of unexplored target space of kinase inhibitors

Cichonska, A.; Ravikumar, B.; Allaway, R. J.; Park, S.; Wan, F.; Isayev, O.; Li, S.; Mason, M. J.; Lamb, A.; Tanoli, Z.-u.-R.; Jeon, M.; Kim, S.; Popova, M.; Zeng, J.; Dang, K.; Koytiger, G.; Kang, J.; Wells, C. I.; Willson, T. M.; The IDG-DREAM Drug-Kinase Binding Prediction Challenge Consortium, ; Oprea, T. I.; Schlessinger, A.; Drewry, D. H.; Stolovitzky, G. A.; Wennerberg, K.; Guinney, J.; Aittokallio, T.

10.1101/2019.12.31.891812 — biochemistry — Posted on 2020-01-07

3156 Origin of the nuclear proteome on the basis of pre-existing nuclear localization signals in prokaryotic proteins

Lisitsyna, O. M.; Kurnaeva, M. A.; Arifulin, E. A.; Shubina, M. Y.; Musinova, Y. R.; Mironov, A. A.; Sheval, E. V.

10.1101/2020.01.07.896449 — evolutionary biology — Posted on 2020-01-07

3157 p27 regulates the autophagy-lysosomal pathway via the control of Ragulator and mTOR activity in amino acid deprived cells

Nowosad, A.; Jeannot, P.; Callot, C.; Creff, J.; Perchey, R. T.; Joffre, C.; Codogno, P.; Manenti, S.; Besson, A.

10.1101/2020.01.07.896860 — cell biology — Posted on 2020-01-07

3158 An Active Chemo-mechanical Model to Predict Adhesion and Microenvironmental Regulation of 3D Cell Shapes

Chen, X.; Boekhorst, V. t.; McEvoy, E.; Friedl, P.; Shenoy, V.

10.1101/2020.01.07.897405 — biophysics — Posted on 2020-01-07

3159 Redox response of iron-sulfur glutaredoxin GRXS17 activates its holdase activity to protect plants from heat stress

Martins, L.; Knuesting, J.; Bariat, L.; Dard, A.; Freibert, S. A.; Marchand, C. H.; Young, D.; Dung, N. H. T.; Debures, A.; Saez-Vasquez, J.; Lemaire, S. D.; Lill, R.; Messens, J.; Scheibe, R.; Reichheld, J.-P.; Riondet, C.

10.1101/2020.01.07.896506 — plant biology — Posted on 2020-01-07

3160 Quantifying Tensile Forces at Cell-Cell Junctions with a DNA-based Fluorescent Probe

Zhao, B.; Li, N.; Xie, T.; Liang, C.; Bagheri, Y.; Sun, Y.; You, M.

10.1101/2020.01.07.897249 — biophysics — Posted on 2020-01-07

3161 GmSALT3 confers shoot Na+ and Cl- exclusion in soybean via two distinct processes.

Qu, Y.; Guan, R.; Bose, J.; Henderson, S. W.; Wege, S.; Qiu, L.-J.; Gilliham, M.

10.1101/2020.01.06.896456 — plant biology — Posted on 2020-01-07

3162 QTL mapping reveals genomic regions for yield based on incremental tolerance index to drought stress and related agronomic traits in canola

Raman, H.; Raman, R.; Mathews, K.; Diffey, D.; Phil Salisbury, P.

10.1101/2020.01.06.896688 — plant biology — Posted on 2020-01-07

3163 Subliminal perception can be predicted from prestimulus activity

Railo, H.; Piccin, R.; Lukasik, K. M.

10.1101/2020.01.06.896803 — neuroscience — Posted on 2020-01-07

3164 A latent variable approach to decoding neural population activity

Whiteway, M. R.; Averbeck, B.; Butts, D. A.

10.1101/2020.01.06.896423 — neuroscience — Posted on 2020-01-07

3165 Electrochemical carbon fiber-based technique for simultaneous recordings of brain tissue PO2, pH, and extracellular field potentials

Hosford, P. S.; Wells, J. A.; Christie, I. N.; Lythgoe, M.; Millar, J.; Gourine, A. V.

10.1101/2020.01.06.895813 — neuroscience — Posted on 2020-01-07

3166 Whole genome comparisons of Staphylococcus agnetis isolates from cattle and chickens

Shwani, A.; Adkins, P. R. F.; Ekesi, N. S.; Alrubaye, A. A.; Calcutt, M. J.; Middleton, J. R.; Rhoads, D. D.

10.1101/2020.01.06.896779 — microbiology — Posted on 2020-01-07

3167 Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling

10.1101/2020.01.06.896365 — microbiology — Posted on 2020-01-07

3168 Antimicrobial activity of the quinoline derivative HT61, effective against non-dividing cells, in Staphylococcus aureus biofilms

Frapwell, C. J.; Skipp, P. J.; Howlin, R. P.; Angus, E. M.; Hu, Y.; Coates, A. R.; Allan, R. N.; Webb, J. S.

10.1101/2020.01.06.896498 — microbiology — Posted on 2020-01-07

3169 Long-term warming weakens stabilizing effects of biodiversity in aquatic ecosystems

Chang, C.-W.; Ye, H.; Miki, T.; Deyle, E. R.; Souissi, S.; Anneville, O.; Adrian, R.; Chiang, Y.-R.; Ichise, S.; Kumagai, M.; Matsuzaki, S.-i. S.; Shiah, F.-K.; Wu, J.-T.; Hsieh, C.-h.; Sugihara, G.

10.1101/2020.01.06.896746 — ecology — Posted on 2020-01-07

3170 A simple, cost-effective, and robust method for rRNA depletion in RNA-sequencing studies

Culviner, P. H.; Guegler, C. K.; Laub, M. T.

10.1101/2020.01.06.896837 — microbiology — Posted on 2020-01-07

3171 Acto-myosin network geometry defines centrosome position

Jimenez, A. J.; de Pascalis, C.; Letort, G.; Vianay, B.; Goldman, R.; Bornens, M.; Piel, M.; Blanchoin, L.; Thery, M.

10.1101/2020.01.07.896969 — cell biology — Posted on 2020-01-07

3172 Overexpression of Thalassiosira pseudonana violaxanthin de-epoxidase-like 2 (VDL2) increases fucoxanthin while stoichiometrically reducing diadinoxanthin cycle pigment abundance

Gaidarenko, O.; Mills, D. W.; Vernet, M.; Hildebrand, M.

10.1101/2020.01.06.896316 — microbiology — Posted on 2020-01-07

3173 Alterations of human lung and gut microbiome in non-small cell lung carcinomas and distant metastasis

Chen, W.-H.; Lu, H.; Gao, N. L.; Wei, C.; Wang, J.; Tong, F.; Li, H.; Zhang, R.; Ma, H.; Yang, N.; Zhang, Y.; Wang, Y.; Liang, Z.; Zeng, H.; Dong, X.

10.1101/2020.01.06.895490 — microbiology — Posted on 2020-01-07

3174 Differential proteomic analysis by SWATH-MS unravels the most dominant mechanisms underlying yeast adaptation to non-optimal temperatures under anaerobic conditions

Pinheiro, T.; Lip, K. Y. F.; Garcia-Rios, E.; Querol, A.; Teixeira, J. A.; van Gulik, W.; Guillamon, J. M.; Domingues, L.

10.1101/2020.01.06.895581 — microbiology — Posted on 2020-01-07

3175 Dysregulation of neural excitability replicates physiological and functional changes in aging visual cortex

Talyansky, S.; Brinkman, B. A. W.

10.1101/2020.01.06.896324 — neuroscience — Posted on 2020-01-07

3176 Controlling brain state prior to stimulation of parietal cortex prevents deterioration of sustained attention

Edwards, G.; Conto, F.; Bucci, L. K.; Battelli, L.

10.1101/2020.01.06.896357 — neuroscience — Posted on 2020-01-07

3177 Recallable but not Recognizable: The Influence of Semantic Priming in Recall Paradigms

Ozubko, J.; Sirianni, L. A.; Ahmad, F.; MacLeod, C.; Addante, R. J.

10.1101/2020.01.06.896795 — neuroscience — Posted on 2020-01-07

3178 Acquisition of Oral Microbiota is Driven by Environment, Not Host Genetics

Mukherjee, C.; Moyer, C. O.; Steinkamp, H. M.; Hashmi, S. B.; Guo, X.; Ni, A.; Leys, E. J.; Griffen, A. L.

10.1101/2020.01.06.896126 — microbiology — Posted on 2020-01-07

3179 Ecological Relationships in the Serengeti National Park

Brownstein, K.

10.1101/2020.01.06.895409 — ecology — Posted on 2020-01-07

3180 Raising the Connectome: the emergence of neuronal activity and behavior in C. elegans

Alicea, B. J.

10.1101/2020.01.06.896308 — developmental biology — Posted on 2020-01-07

3181 Context-dependent odor learning requires the anterior olfactory nucleus

Levinson, M.; Alexandrou, G.; Kolenda, J.; Escanilla, O.; Smith, D. M.; Cleland, T. A.; Linster, C.

10.1101/2020.01.06.895961 — neuroscience — Posted on 2020-01-07

3182 Improving the sensitivity of cluster-based statistics for fMRI data

Geerligs, L.; Maris, E.

10.1101/2020.01.06.896167 — neuroscience — Posted on 2020-01-07

3183 Navigational strategies underlying temporal phototaxis in Drosophila larvae

Zhu, M. L.; Herrera, K. J.; Vogt, K.; Bahl, A.

10.1101/2020.01.06.896142 — animal behavior and cognition — Posted on 2020-01-07

3184 Sensory gating precedes motor command in evolution of the corticospinal tract

Moreno, Y.; Bichara, C.; Isope, P.; Cordero-Erausquin, M.

10.1101/2020.01.06.895912 — neuroscience — Posted on 2020-01-07

3185 Free-water metrics in medial temporal lobe white matter tract projections relate to longitudinal cognitive decline

Archer, D. B.; Moore, E. E.; Shashikumar, N.; Dumitrescu, L.; Pechman, K.; Landman, B.; Gifford, K.; Jefferson, A.; Hohman, T.

10.1101/2020.01.06.896217 — neuroscience — Posted on 2020-01-07

3186 Spinal stretch reflexes support efficient control of reaching

Weiler, J.; Gribble, P. L.; Pruszynski, J. A.

10.1101/2020.01.06.896225 — neuroscience — Posted on 2020-01-07

3187 Hybridization capture of larch (Larix Mill.) chloroplast genomes from sedimentary ancient DNA reveals past changes of Siberian forests

Schulte, L.; Bernhardt, N.; Stoof-Leichsenring, K. R.; Zimmermann, H. H.; Pestryakova, L. A.; Epp, L. S.; Herzschuh, U.

10.1101/2020.01.06.896068 — ecology — Posted on 2020-01-07

3188 Individual variability in functional organization of the human and monkey auditory cortex

Ren, J.; Liu, H.; Xu, T.; Schoeppe, F.; Wang, D.; Li, M.; Lin, Y.; Ramirez, J.; Lu, J.; Li, L.; Ahveninen, J.

10.1101/2020.01.06.895474 — neuroscience — Posted on 2020-01-07

3189 In vivo molecular signatures of cerebellar pathology in spinocerebellar ataxia type 3

Costa, M. d. C.; Radzwion, M.; McLoughlin, H. S.; Ashraf, N. S.; Fisher, S.; Shakkottai, V. G.; Maciel, P.; Paulson, H. L.; Oz, G.

10.1101/2020.01.03.894337 — neuroscience — Posted on 2020-01-07

3190 A comprehensive and comparative study on the action of pentacyclic triterpenoids on Vibrio cholerae biofilms.

Paul Bhattacharya, S.; Bhattacharya, A.; Sen, A.

10.1101/2020.01.06.896183 — microbiology — Posted on 2020-01-07

3191 Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at Chr16q11.2 and on the MAPT H1 allele.

Soutar, M.; Melandri, D.; Annuario, E.; Monaghan, A.; Welsh, N.; D'Sa, K.; Guelfi, S.; Zhang, D.; Pittman, A.; Trabzuni, D.; Pan, K.; Kia, D. A.; Bictash, M.; Gandhi, S.; Houlden, H.; Cookson, M. R.; Wood, N.; Singleton, A.; Hardy, J.; Whiting, P.; Blauwendraat, C.; Whitworth, A.; Manzoni, C.; Ryten, M.; Lewis, P.; Plun-Favreau, H.

10.1101/2020.01.06.896241 — neuroscience — Posted on 2020-01-07

3192 Aurora B and Condensin are dispensable for chromosome arm and telomere separation during meiosis II

Berthezene, J.; Reyes, C.; Li, T.; Coulon, S.; Bernard, P.; Gachet, Y.; Tournier, S.

10.1101/2020.01.07.897033 — cell biology — Posted on 2020-01-07

3193 Glacier ice archives fifteen-thousand-year-old viruses

Zhong, Z.-P.; Solonenko, N. E.; Li, Y.-F.; Gazitua, M. C.; Roux, S.; Davis, M. E.; Van Etten, J. L.; Mosley-Thompson, E.; Rich, V. I.; Sullivan, M. B.; Thompson, L. G.

10.1101/2020.01.03.894675 — ecology — Posted on 2020-01-07

3194 In-depth 15 H7N9 Human Serum Proteomics Profiling Study

Yang, Z.; Guan, W.; Zhou, S.; Chen, L.; Mok, C. K. P.; Huang, J.; Wu, S.; Zhou, H.; Liu, Y.; Peiris, J. S. M.; Liu, X.; Li, Y.; Zhong, N.

10.1101/2020.01.06.896829 — molecular biology — Posted on 2020-01-07

3195 Towards XNA molecular biology: Bacterial cell display as a robust and versatile platform for the engineering of low affinity ligands and enzymes

Csibra, E.; Renders, M.; Pinheiro, V. B.

10.1101/2020.01.06.896050 — synthetic biology — Posted on 2020-01-07

3196 Transcriptional and Cellular Diversity of the Human Heart

Tucker, N. R.; Chaffin, M.; Fleming, S. J.; Hall, A. W.; Parsons, V. A.; Bedi, K.; Akkad, A.-D.; Herndon, C. N.; Arduini, A.; Papangeli, I.; Roselli, C.; Aguet, F.; Choi, S. H.; Ardlie, K. G.; Babadi, M.; Margulies, K. B.; Stegmann, C. M.; Ellinor, P. T.

10.1101/2020.01.06.896076 — genomics — Posted on 2020-01-07

3197 Tracing the evolutionary history and global expansion of Candida auris using population genomic analyses

Chow, N. A.; Munoz, J. F.; Gade, L.; Berkow, E.; Li, X.; Welsh, R. M.; Forsberg, K.; Lockhart, S. R.; Adam, R.; Alanio, A.; Alastruey-Izquierdo, A.; Althawadi, S.; Belen Arauz, A.; Ben-Ami, R.; Bharat, A.; Calvo, B. C.; Desnos-Ollivier, M.; Escandon, P.; Gardam, D.; Gunturu, R.; Heath, C. H.; Kurzai, O.; Martin, R.; Litvintseva, A. P.; Cuomo, C.

10.1101/2020.01.06.896548 — genomics — Posted on 2020-01-07

3198 Discovery of peculiar cells in the peri-tumoral regions and peripheral blood of glioblastoma patients by single cell RNA-sequencing

Yang, R.; Huang, G.; Guo, J.; Li, Y.; Song, H.; Li, K.; Yi, G.; Lin, Z.; Wang, X.; Xie, S.; Liu, Z.; Shi, X.; Li, K.; Qi, S.; Liu, Y.

10.1101/2020.01.06.895987 — cancer biology — Posted on 2020-01-07

3199 Risk factors associated with canine overweightness and obesity in an owner-reported survey

Perry, L. M.; Shmalberg, J.; Tanprasertsuk, J.; Massey, D.; Honaker, R. W.; Jha, A. R.

10.1101/2020.01.06.896399 — bioinformatics — Posted on 2020-01-07

3200 MINREACT: an efficient algorithm for identifying minimal metabolic networks

Sambamoorthy, G.; Raman, K.

10.1101/2020.01.06.896084 — systems biology — Posted on 2020-01-07

3201 Engineering E. coli for magnetic control and the spatial localization of functions

Aubry, M.; Wang, W.-A.; Guyodo, Y.; Delacou, E.; Guignier, J. M.; Espeli, O.; Lebreton, A.; Guyot, F.; Gueroui, Z.

10.1101/2020.01.06.895623 — synthetic biology — Posted on 2020-01-07

3202 Genome-wide comparison of DNA methylation between life cycle stages of Drosophila melanogaster using high-throughput sequencing techniques.

Deshmukh, S.; Abhyankar, V.; Karuthedath Vellarikkal, S.; Sivasubbu, S.; Scaria, V.; Deobagkar, D. D.

10.1101/2020.01.06.895920 — genomics — Posted on 2020-01-07

3203 Measuring genetic variation in the multi-ethnic Million Veteran Program (MVP)

Hunter-Zinck, H.; Shi,, Y.; Li, M.; Gorman, B. R.; Ji, S.-G.; Sun, N.; Webster, T.; Liem, A.; Hsieh, P.; Devineni, P.; Karnam, P.; Radhakrishnan, L.; Schmidt, J.; Assimes, T. L.; Huang, J.; Pan, C.; Humphries, D.; Brophy, M.; Moser, J.; Muralidhar, S.; Huang, G. D.; Przygodzki, R.; Concato, J.; Gaziano, J. M.; Gelernter, J.; ODonnell, C. J.; Hauser, E. R.; Zhao, H.-y.; OLeary, T. J.; Tsao, P. S.; Pyarajan, S.

10.1101/2020.01.06.896613 — genetics — Posted on 2020-01-07

3204 Invertebrate Metaxins 1 and 2: Widely Distributed Proteins Homologous to Vertebrate Metaxins Implicated in Protein Import into Mitochondria

Adolph, K. W.

10.1101/2020.01.06.895979 — evolutionary biology — Posted on 2020-01-07

3205 Regulation of HDAC2-PDX1 by RNF125 defines pancreatic cancer development

Hasnis, E.; Kim, H.; Verma, S.; Feng, Y.; Almog, R.; Matsliah, S.; Vavinskaya, V.; Alelbaum, R.; Ben-Ishay, O.; Tuveson, D.; Sears, R.; Ronai, Z. A.

10.1101/2020.01.06.896555 — cancer biology — Posted on 2020-01-07

3206 Protein sequence design with a learned potential

Anand, N.; Eguchi, R. R.; Derry, A.; Altman, R. B.; Huang, P.

10.1101/2020.01.06.895466 — bioinformatics — Posted on 2020-01-07

3207 barCoder: a tool to generate unique, orthogonal genetic tags for qPCR detection

Bernhards, C. B.; Lux, M. W.; Katoski, S. E.; Goralski, T. D.; Liem, A. T.; Gibbons, H. S.

10.1101/2020.01.06.896035 — bioinformatics — Posted on 2020-01-07

3208 Supervised Adversarial Alignment of scRNA-seq Data

Ge, S.; Wang, H.; Alavi, A.; Xing, E.; Bar-Joseph, Z.

10.1101/2020.01.06.896621 — bioinformatics — Posted on 2020-01-07

3209 Identification of a PRC2 accessory subunit required for subtelomeric H3K27 methylation in Neurospora

McNaught, K. J.; Wiles, E. T.; Selker, E. U.

10.1101/2020.01.06.896845 — molecular biology — Posted on 2020-01-07

3210 Integrative molecular profiling of autoreactive CD4 T cells in autoimmune hepatitis

Renaud, A.; Cervera-Marzal, I.; Gil, L.; Dong, C.; Kervagoret, E.; Auble, H.; Habes, S.; Cardon, A.; Judor, J.-P.; Mosnier, J.-F.; Brouard, S.; Gournay, J.; Milpied, P.; Conchon, S.

10.1101/2020.01.06.895938 — immunology — Posted on 2020-01-07

3211 Single-cell analysis of human embryos reveals diverse patterns of aneuploidy and mosaicism

Starostik, M. R.; Sosina, O. A.; McCoy, R. C.

10.1101/2020.01.06.894287 — genomics — Posted on 2020-01-07

3212 A new domestic cat genome assembly based on long sequence reads empowers feline genomic medicine and identifies a novel gene for dwarfism.

Buckley, R. M.; Davis, B. W.; Brashear, W. A.; Farias, F. H. G.; Kuroki, K.; Graves, T.; Hillier, L. W.; Kremitzki, M.; Li, G.; Middleton, R.; Minx, P. M.; Tomlinson, C.; Lyons, L. A.; Murphy, W. J.; Warren, W. C.

10.1101/2020.01.06.896258 — genomics — Posted on 2020-01-07

3213 Pleiotropic effect of ABCG2 in gout: involvement in serum urate levels and progression from hyperuricemia to gout

Wrigley, R.; Phipps-Green, A.; Topless, R.; Major, T.; Cadzow, M.; Riches, P.; Tausche, A.-K.; Jansen, M.; Joosten, L.; Jansen, T.; So, A.; Harre Hindmarsh, J.; Stamp, L.; Dalbeth, N.; Merriman, T.

10.1101/2020.01.06.894899 — genetics — Posted on 2020-01-07

3214 Phylogenomics unravels speciation patterns in temperate-montane plant species: a case study on the recently radiating Ranunculus auricomus species complex

Tomasello, S.; Karbstein, K.; Hodac, L.; Paetzold, C.; Hoerandl, E.

10.1101/2020.01.06.895904 — evolutionary biology — Posted on 2020-01-07

3215 Identifying strategies to target the metabolic flexibility of tumours.

Yuneva, M.; Mendez-Lucas, A.; Lin, W.; Driscoll, P. C.; Legrave, N.; Novellasdemunt Vilaseca, L.; Xie, C.; Charles, M.; Wilson, Z.; Jones, N. P.; Rayport, S. G.; Rodriguez-Justo, M.; Li, V. S. W.; MacRae, J. I.; Hay, N.; Chen, X.

10.1101/2020.01.06.896571 — cancer biology — Posted on 2020-01-07

3216 Scanning electron microscopy preparation and analysis of the cell cortex ultrastructure

Flormann, D.; Schu, M.; Terriac, E.; Koch, M.; Paschke, S.; Lautenschlaeger, F.

10.1101/2020.01.06.896761 — biophysics — Posted on 2020-01-07

3217 Revisiting and expanding the meta-analysis of variation: The log coefficient of variation ratio, lnCVR

Senior, A. M.; Viechtbauer, W.; Nakagawa, S.

10.1101/2020.01.06.896522 — bioinformatics — Posted on 2020-01-07

3218 Resolving brain organoid heterogeneity by mapping single cell genomic data to a spatial reference

Fleck, J. S.; He, Z.; Boyle, M. J.; Camp, J. G.; Treutlein, B.

10.1101/2020.01.06.896282 — bioinformatics — Posted on 2020-01-07

3219 Uncovering antibody cross-reaction dynamics in influenza A infections

Hernandez Mejia, G.; Hernandez Vargas, E. A.

10.1101/2020.01.06.896274 — systems biology — Posted on 2020-01-07

3220 Laboratory testing of very low-copper-treated water to prolong pupation and emerging time of mosquito larvae: an alternative method to delay mosquito breeding capability

Reza, M.; Ilmiawati, C.

10.1101/871400 — zoology — Posted on 2020-01-07

3221 Depletion of the AD risk gene SORL1 selectively impairs neuronal endosomal traffic independent of amyloidogenic APP processing

Knupp, A.; Mishra, S.; Martinez, R.; Braggin, J.; Szabo, M.; Hailey, D. W.; Small, S. A.; Jayadev, S.; Young, J. E.

10.1101/2020.01.06.896670 — cell biology — Posted on 2020-01-06

3222 Constructing early diagnosis model of colorectal cancer based on expression profile

wang, s.; wang, y.; wang, s.

10.1101/2020.01.06.895730 — genetics — Posted on 2020-01-06

3223 PEDF-Rpsa-Itga6 signaling regulates cortical neuronal morphogenesis

Blazejewski, S. M.; Bennison, S. A.; Ha, N.; Liu, X.; Smith, T. H.; Dougherty, K. J.; Toyooka, K.

10.1101/2020.01.06.895672 — neuroscience — Posted on 2020-01-06

3224 Fonsecaea pedrosoi conidia and hyphae activate neutrophils distinctly: Requirement of TLR-2 and TLR-4 in neutrophil effector functions

Breda, L. C. D.; Breda, C. N. d. S.; de Almeida, J. R. F.; Paulo, L. N. M.; Jannuzzi, G. P.; Menezes, I. d. G.; Albuquerque, R. C.; Camara, N. O. S.; Ferreira, K. S.; Almeida, S. R.

10.1101/2020.01.06.895706 — immunology — Posted on 2020-01-06

3225 Strategic Inattention in the Sir Philip Sidney Game

Whitmeyer, M.

10.1101/559955 — evolutionary biology — Posted on 2020-01-06

3226 MAPPING TRENDS IN INSECTICIDE RESISTANCE PHENOTYPES IN AFRICAN MALARIA VECTORS

Hancock, P.; Hendriks, C.; Tangena, J.-A.; Gibson, H.; Coleman, M.; Gething, P.; Cameron, E.; Bhatt, S.; Moyes, C.

10.1101/2020.01.06.895656 — ecology — Posted on 2020-01-06

3227 Structural basis for catalysis and substrate specificity of human ACAT1

Qian, H.; Zhao, X.; Yan, R.; Gao, S.; Sun, X.; Wong, C. C. L.; Yan, N.

10.1101/2020.01.06.896597 — biochemistry — Posted on 2020-01-06

3228 The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for human complex diseases

Xu, F.; Fu, Y.; Sun, T.-y.; Jiang, Z.; Miao, Z.; Shuai, M.; Gou, W.; Ling, C.-w.; Yang, J.; Wang, J.; Chen, Y.-m.; Zheng, J.-S.

10.1101/2019.12.26.888313 — microbiology — Posted on 2020-01-06

3229 Mechanical control of morphogenesis robustness

Martin, E.; Theis, S.; Gay, G.; Monier, B.; Suzanne, M.

10.1101/2020.01.06.896266 — developmental biology — Posted on 2020-01-06

3230 RFDTI: Using Rotation Forest with Feature Weighted for Drug-Target Interaction Prediction from Drug Molecular Structure and Protein Sequence

wang, l.; You, Z.-H.; Li, L.-P.; Yan, X.

10.1101/2020.01.06.895755 — bioinformatics — Posted on 2020-01-06

3231 Phosphorylation of the overlooked tyrosine 310 regulates the structure, aggregation, and microtubule- and lipid-binding properties of Tau

Ait-Bouziad, N.; Chiki, A.; Limorenko, G.; Xiao, S.; Eliezer, D.; Lashuel, H.

10.1101/2020.01.06.896381 — biochemistry — Posted on 2020-01-06

3232 Lipid-specific labeling of enveloped viruses with quantum dots for single-virus tracking

Zhang, L.-J.; Wang, S.; Xia, L.; Lv, C.; Tang, H.-W.; Xiao, G.; Pang, D.-W.

10.1101/2020.01.06.895805 — biochemistry — Posted on 2020-01-06

3233 Neurodegenerative disease-associated protein aggregates are poor inducers of the heat shock response in neuronal-like cells

San Gil, R.; Cox, D.; McAlary, L.; Berg, T.; Walker, A. K.; Yerbury, J. J.; Ooi, L.; Ecroyd, H.

10.1101/2020.01.06.896654 — cell biology — Posted on 2020-01-06

3234 Hydrodynamic model of directional ciliary-beat organization in human airways

Gsell, S.; Loiseau, E.; D'Ortona, U.; Viallat, A.; Favier, J.

10.1101/2020.01.06.896001 — biophysics — Posted on 2020-01-06

3235 Simulation of the Gαq /Phospholipase Cβ1 Signaling Pathway Returns Differentiated PC12 Cells to a Stem-like State

Garwain, O.; Pearce, K. M.; Jackson, L.; Carley, S.; Rosati, B.; Scarlata, S. S.

10.1101/2020.01.06.896530 — biochemistry — Posted on 2020-01-06

3236 Structure and mechanism of human diacylglycerol acyltransferase 1

Wang, L.; Qian, H.; Nian, Y.; Han, Y.; Ren, Z.; Zhang, H.; Hu, L.; Prasad, B. V. V.; Yan, N.; Zhou, M.

10.1101/2020.01.06.896332 — biochemistry — Posted on 2020-01-06

3237 Unraveling the aggregation dynamics of amyloidogenesis: A data-driven mathematical modeling approach

Tikader, B.; Maji, S. K.; Kar, S.

10.1101/2020.01.06.895649 — systems biology — Posted on 2020-01-06

3238 Brain signatures of surprise in EEG and MEG data

Mousavi, Z.; Kiani, M. M.; Aghajan, H.

10.1101/2020.01.06.895664 — neuroscience — Posted on 2020-01-06

3239 The conserved herpesviral kinase ORF36 activates B2 retrotransposons during murine gammaherpesvirus infection

Schaller, A.; Tucker, J.; Willis, I. M.; Glaunsinger, B. A.

10.1101/2020.01.06.895789 — molecular biology — Posted on 2020-01-06

3240 Multidrug Resistance and High Prevalence of class 1 Integrons in Escherichia coli Isolated from Irrigation Water and Vegetables in Parts of Nsukka and Enugu, Nigeria

Chigor, V. N.; Chigor, C. B.; Ibangha, I.-A. I.; Nweze, N. O.; Ozochi, C. A.; Onuora, V. C.; Titilawo, Y.; Chernikova, T. N.; Golyshin, P. N.

10.1101/2020.01.06.895748 — microbiology — Posted on 2020-01-06

3241 Correlation-based and feature-driven mutation signature analyses to identify genetic features associated with DNA mutagenic processes in cancer genomes

Jeong, H. Y.; Yoo, J.; Kim, H.; Kim, T.-M.

10.1101/2020.01.06.895698 — genomics — Posted on 2020-01-06

3242 Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophase

Slotman, J.; Paul, M.; Carofiglio, F.; de Gruiter, H. M.; Vergroesen, T.; van Cappellen, W.; Houtsmuller, A.; Baarends, W. M.

10.1101/2020.01.06.895680 — developmental biology — Posted on 2020-01-06

3243 Deep Learning Enhanced Hyperspectral Fluorescence Lifetime Imaging

Mendoza, M. I. O.; Rudkouskaya, A.; Yao, R.; Yan, P.; Barroso, M.; Intes, X.

10.1101/2020.01.06.896092 — biophysics — Posted on 2020-01-06

3244 Parkinson's Disease-linked LRRK2 structure and model for microtubule interaction

Deniston, C. K.; Salogiannis, J.; Mathea, S.; Snead, D. M.; Lahiri, I.; Donosa, O.; Watanabe, R.; Böhning, J.; Shiau, A. K.; Knapp, S.; Villa, E.; Reck-Peterson, S. L.; Leschziner, A. E.

10.1101/2020.01.06.895367 — biophysics — Posted on 2020-01-06

3245 Platelet, erythrocyte, endothelial, and monocyte microparticles in coagulation activation and propagation

Lipets, E.; Antonova, O.; Shustova, O.; Losenkova, K.; Mazurov, A.; Ataullakhanov, F.

10.1101/2020.01.06.895722 — biophysics — Posted on 2020-01-06

3246 "Pain in my heart": Understanding perinatal depression among women living with HIV in Malawi

LeMasters, K.; Dussault, J.; Barrington, C.; Bengtson, A.; Gaynes, B.; Go, V.; Hosseinipour, M. C.; Kulisewa, K.; Kutengule, A.; Meltzer-Brody, S.; Midiani, D.; Mphonda, S.; Udedi, M.; Pence, B.

10.1101/2020.01.06.895763 — scientific communication and education — Posted on 2020-01-06

3247 ILC1-derived IFN-gamma mediates cDC1-dependent host resistance against Toxoplasma gondii

Yarovinsky, F.; Lopez-Yglesias, A.; Burger, E.; Camanzo, E.; Martin, A.; Araujo, A.; Kwok, S.

10.1101/2020.01.06.895771 — immunology — Posted on 2020-01-06

3248 Evolutionarily Conserved Transcription Factors Drive the Oxidative Stress Response in Drosophila

Ryan, S. M.; Wildman, K.; Oceguera-Perez, B.; Barbee, S.; Mortimer, N. T.; Vrailas-Mortimer, A.

10.1101/735126 — evolutionary biology — Posted on 2020-01-06

3249 A possible coding for experience: ripple-like events and synaptic diversity

Ishikawa, J.; Tomokage, T.; Mitsushima, D.

10.1101/2019.12.30.891259 — animal behavior and cognition — Posted on 2020-01-06

3250 Effect of Exogenous Amino Acids on Yield and Quality of Tartary Buckwheat in Non-saline and Saline-alkali Soil

Song, J.-N.; Wang, Y.-Q.; Li, S.; Li, F.-L.; Hu, Y.-J.; Yang, H.-B.

10.1101/2019.12.24.887778 — physiology — Posted on 2020-01-06

3251 Quantification of nosZ genes and transcripts in activated sludge microbiomes with novel group-specific qPCR methods validated with metagenomic analyses

Kim, D. D.; Park, D.; Yoon, H.; Song, M. J.; Yun, T.; Yoon, S.

10.1101/710483 — microbiology — Posted on 2020-01-06

3252 Transcriptome analysis reveals salinity responses in four Tartary buckwheat cultivars

Song, J.-N.; Liu, X.-H.; Wang, Y.-Q.; Yang, H.-B.

10.1101/869263 — genomics — Posted on 2020-01-06

3253 Beta 1 Integrin Signaling Mediates Pancreatic Ductal Adenocarcinoma Resistance to MEK Inhibition

Brannon, A.; Drouillard, D.; Steele, N.; Sutherland, S.; Crawford, H.; Pasca di Magliano, M.

10.1101/862482 — cancer biology — Posted on 2020-01-06

3254 Thrombospondin-4 mediates hyperglycemia- and TGF-beta-induced inflammation in breast cancer

Muppala, S.; Xiao, R.; Gajeton, J.; Verbovetskiy, D.; Krukovets, I.; Stenina-Adognravi, O.

10.1101/2020.01.03.894436 — cancer biology — Posted on 2020-01-06

3255 Highly heterogeneous long-range interactions explain chromosome compartmentalization

Eidelman, Y. A.; Salnikov, I. V.; Slanina, S. V.; Andreev, S.

10.1101/2019.12.29.890459 — biophysics — Posted on 2020-01-06

3256 A Novel Chloroplast Super-Complex Consisting of the ATP Synthase and Photosystem I Reaction Center

Bhaduri, S.; Singh, S. K.; Cohn, W.; Hasan, S. S.; Whitelegge, J. P.; Cramer, W. A.

10.1101/2019.12.25.888495 — biochemistry — Posted on 2020-01-06

3257 ETHYLENE RESPONSE FACTOR 115 integrates jasmonate and cytokinin signaling machineries to repress adventitious rooting in Arabidopsis

Lakehal, A.; Dob, A.; Rahneshan, Z.; Novak, O.; Escamez, S.; Alallaq, S.; Strnad, M.; Tuominen, H.; Bellini, C.

10.1101/2019.12.27.886796 — plant biology — Posted on 2020-01-06

3258 Electrophysiological network alterations in adults with copy number variants associated with high neurodevelopmental risk

Dima, D. C.; Adams, R.; Linden, S. C.; Baird, A.; Smith, J.; Foley, S.; Perry, G.; Routley, B. C.; Magazzini, L.; Drakesmith, M.; Williams, N.; Doherty, J.; van den Bree, M. B.; Owen, M. J.; Hall, J.; Linden, D. E. J.; Singh, K. D.

10.1101/753145 — neuroscience — Posted on 2020-01-06

3259 Mutation of a PER2 phosphodegron perturbs the circadian phosphoswitch

Masuda, S.; Narasimamurthy, R.; Yoshitane, H.; Kim, J. K.; Fukada, Y.; Virshup, D. M.

10.1101/2019.12.16.876615 — molecular biology — Posted on 2020-01-06

3260 Rough and smooth variant Mycobacterium abscessus infections are differentially controlled by host immunity during chronic infection of adult zebrafish

Hortle, E.; Kam, J. Y.; Krogman, E.; Warner, S. E.; Manuneedhi Cholan, P.; Kikuchi, K.; Triccas, J. A.; Britton, W. J.; Johansen, M. D.; Kremer, L.; Oehlers, S. H.

10.1101/856948 — microbiology — Posted on 2020-01-06

3261 Adenosine signaling and its downstream target mod(mdg4) modify the pathogenic effects of polyglutamine in a Drosophila model of Huntington's disease

Lin, Y.-H.; Ouns Maaroufi, H.; Kucerova, L.; Rouhova, L.; Filips, T.; Zurovec, M.

10.1101/2019.12.22.886143 — genetics — Posted on 2020-01-06

3262 Moderate amounts of epistasis are not evolutionarily stable in small populations

Sydykova, D. K.; LaBar, T. O.; Adami, C.; Wilke, C. O.

10.1101/752535 — evolutionary biology — Posted on 2020-01-06

3263 Single-cell epigenomic identification of inherited risk loci in Alzheimer's and Parkinson's disease

Corces, M. R.; Shcherbina, A.; Kundu, S.; Gloudemans, M. J.; Fresard, L.; Granja, J. M.; Louie, B. H.; Shams, S.; Bagdatli, S. T.; Mumbach, M. R.; Liu, B.; Montine, K. S.; Greenleaf, W. J.; Kundaje, A.; Montgomery, S. B.; Chang, H. Y.; Montine, T. J.

10.1101/2020.01.06.896159 — genomics — Posted on 2020-01-06

3264 XenoCP: Cloud-based BAM cleansing tool for RNA and DNA from Xenograft

arunachalam, s.; Zhang, J.; Rusch, M.; Ding, L.; Thrasher, A.; Dyer, M.; Baker, S.; Jin, H.; Macias, M.; Kasper, L.

10.1101/843250 — bioinformatics — Posted on 2020-01-06

3265 Impact of second-generation antipsychotics on white matter microstructure in adolescent-onset psychosis.

Barth, C.; Lonning, V.; Gurholt, T. P.; Andreassen, O. A.; Myhre, A. M.; Agartz, I.

10.1101/721225 — neuroscience — Posted on 2020-01-06

3266 A transcriptional regulatory atlas of human pancreatic islets reveals non-coding functional signatures at GWAS loci

Varshney, A.; Kyono, Y.; Elangovan, V. R.; Wang, C.; Erdos, M. R.; Narisu, N.; Albanus, R. D. O.; Orchard, P.; Stitzel, M. L.; Collins, F. S.; Kitzman, J. O.; Parker, S. C. J.

10.1101/812552 — genomics — Posted on 2020-01-06

3267 Reanalysis And Integration Of Public Microarray Datasets Reveals Novel Host Genes Modulated In Leprosy

Leal-Calvo, T.; Moraes, M. O.

10.1101/824805 — genomics — Posted on 2020-01-06

3268 Efficient toolkit implementing best practices for principal component analysis of population genetic data

Prive, F.; Luu, K.; Blum, M. G. B.; McGrath, J. J.; Vilhjalmsson, B. J.

10.1101/841452 — genetics — Posted on 2020-01-06

3269 A Unifying Mechanistic Model of the Auditory Cortex with Inhibitory Subtypes

Park, Y.; Geffen, M. N.

10.1101/626358 — neuroscience — Posted on 2020-01-06

3270 Auditory cortex shapes sound responses in the inferior colliculus.

Blackwell, J. M.; Lesicko, A.; Rao, W.; De Biasi, M.; Geffen, M. N.

10.1101/584334 — neuroscience — Posted on 2020-01-06

3271 Cerebellar Purkinje cell activity modulates aggressive behavior

Jackman, S. L.; Chen, C. H.; Offermann, H. L.; Drew, I. R.; Harrison, B. M.; Bowman, A. M.; Flick, K. M.; Flaquer, I.; Regehr, W. G.

10.1101/2020.01.06.891127 — neuroscience — Posted on 2020-01-06

3272 Identification and biochemical characterization of a novel eukaryotic-like Ser/Thr kinase in E. coli

Rajagopalan, K.; Dworkin, J.

10.1101/819920 — microbiology — Posted on 2020-01-06

3273 SPINT2 inhibits proteases involved in activation of both influenza viruses and metapneumoviruses

Straus, M.; Kinder, J. T.; Segall, M.; Dutch, R. E.; Whittaker, G. R.

10.1101/752592 — microbiology — Posted on 2020-01-06

3274 dream: Powerful differential expression analysis for repeated measures designs

Hoffman, G. E.; Roussos, P.

10.1101/432567 — genomics — Posted on 2020-01-06

3275 Indication of a reduction in the cover of thin-leaved plants in Danish grasslands over an eight-year period

Damgaard, C.

10.1101/735472 — ecology — Posted on 2020-01-06

3276 Spectral cues are necessary to encode azimuthal auditory space in the mouse superior colliculus

Ito, S.; Si, Y.; Feldheim, D. A.; Litke, A. M.

10.1101/704031 — neuroscience — Posted on 2020-01-06

3277 Endothelial CXCL5 negatively regulates myelination and repair after white matter stroke

Xiao, G.; Kumar, R.; Komuro, Y.; Burguet, J.; Kakarla, V.; Azizkhanian, I.; Sheth, S. A.; Williams, C. K.; Zhang, X. R.; Macknicki, M.; Brumm, A.; Kawaguchi, R.; Mai, P.; Kaneko, N.; Vinters, H. V.; Carmichael, S. T.; Havton, L. A.; DeCarli, C.; Hinman, J. D.

10.1101/664953 — neuroscience — Posted on 2020-01-06

3278 Tracking the mind's eye: Primate gaze behavior during virtual visuomotor navigation reflects belief dynamics

Lakshminarasimhan, K. J.; Avila, E.; Neyhart, E.; DeAngelis, G. C.; Pitkow, X.; Angelaki, D. E.

10.1101/689786 — animal behavior and cognition — Posted on 2020-01-06

3279 Phanerozoic Radiation of Ammonia Oxidizing Bacteria

Ward, L. M.; Johnston, D.; Shih, P. M.

10.1101/655399 — evolutionary biology — Posted on 2020-01-06

3280 Tiled Reconstruction Improves Structured Illumination Microscopy

Hoffman, D. P.; Betzig, E.

10.1101/2020.01.06.895318 — cell biology — Posted on 2020-01-06

3281 A complex view of GPCR signaling: Multidimensional analysis of extended molecular dynamics simulations reveals the complexity of signal transduction by the histamine H3 membrane receptor

Herrera-Zuniga, L. D.; Moreno-Vargas, L. M.; Correa-Basurto, J.; Prada, D.; Curmi, P.; Arrang, J.-M.; Maroun, R. C.

10.1101/604793 — bioinformatics — Posted on 2020-01-06

3282 A flexible microfluidic system for single-cell transcriptome profiling elucidates phased transcriptional regulators of cell cycle

Davey, K.; Wong, D.; Konopacki, F.; Kwa, E.; Fiegler, H.; Sibley, C. R.

10.1101/2020.01.06.895524 — genomics — Posted on 2020-01-06

3283 Improved multi-type birth-death phylodynamic inference in BEAST 2

Scire, J.; Barido-Sottani, J.; Kuehnert, D.; Vaughan, T. G.; Stadler, T.

10.1101/2020.01.06.895532 — evolutionary biology — Posted on 2020-01-06

3284 The 'hidden side' of spin labeled oligonucleotides: Molecular Dynamics study focusing on the EPR-silent components of base pairing

Dantu, S. C.; Sicoli, G.; Höbartner, C.

10.1101/537324 — biophysics — Posted on 2020-01-06

3285 Myosin X interaction with KIF13B, a crucial pathway for Netrin-1-induced axonal development

Yu, H.-L.; Peng, Y.; Zhao, Y.; Lan, Y.-S.; Wang, B.; Zhao, L.; Sun, D.; Pan, J.-X.; Dong, Z.; Mei, L.; Ding, Y.-Q.; Zhu, X.-J.; Xiong, W.-C.

10.1101/2020.01.06.896100 — developmental biology — Posted on 2020-01-06

3286 Functions of olfactory receptors are decoded from their sequence

Cong, X.; Ren, W.; Pacalon, J.; de March, C. A.; Xu, L.; Matsunami, H.; Yu, Y.; Golebiowski, J.

10.1101/2020.01.06.895540 — bioinformatics — Posted on 2020-01-06

3287 Mesophasic organization of GABAA receptors in hippocampal inhibitory synapse

Liu, Y.-T.; Tao, C.-L.; Zhang, X.; Qi, L.; Sun, R.; Lau, P.-M.; Zhou, H.; Bi, G.-Q.

10.1101/2020.01.06.895425 — neuroscience — Posted on 2020-01-06

3288 Late onset of Syt2a expression at synapses relevant to social behavior

Goode, C.; Vouen, M.; Ncube, D.; Eisen, J.; Washbourne, P.; Tallafuss, A.

10.1101/2020.01.06.895508 — neuroscience — Posted on 2020-01-06

3289 Exactly solvable models of stochastic gene expression

Ham, L.; Schnoerr, D.; Brackston, R. D.; Stumpf, M. P. H.

10.1101/2020.01.05.895359 — systems biology — Posted on 2020-01-06

3290 Mutations in the tomato gibberellin receptors suppresses xylem proliferation and reduces water loss under water-deficit conditions

Illouz-Eliaz, N.; Nissan, I.; Nir, I.; Ramon, U.; Shohat, H.; Weiss, D.

10.1101/2020.01.06.895011 — plant biology — Posted on 2020-01-06

3291 Spatial accumulation of salicylic acid is in effector-triggered immunity of potato against viruses regulated by RBOHD

Lukan, T.; Pompe-Novak, M.; Baebler, S.; Tusek-Znidaric, M.; Kladnik, A.; Kriznik, M.; Blejec, A.; Zagorscak, M.; Stare, K.; Dusak, B.; Coll, A.; Pollmann, S.; Morgiewicz, K.; Hennig, J.; Gruden, K.

10.1101/2020.01.06.889998 — plant biology — Posted on 2020-01-06

3292 Capturing volumetric dynamics at high speed in the brain by confocal light field microscopy

Zhang, Z.; Bai, L.; Cong, L.; Yu, P.; Zhang, T.; Shi, W.; Li, F.; Du, J.; Wang, K.

10.1101/2020.01.04.890624 — neuroscience — Posted on 2020-01-06

3293 A qualitative difference in decision-making of rats vs. humans explained by quantitative differences in behavioral variability

Nguyen, Q. N.; Reinagel, P.

10.1101/2020.01.05.895268 — neuroscience — Posted on 2020-01-06

3294 The G-protein coupled receptor SRX-97 is required for concentration dependent sensing of Benzaldehyde in Caenorhabditis elegans

Kadam, N. Y.; Behera, S.; Kumar, S.; Ghosh-Roy, A.; Babu, K.

10.1101/2020.01.04.894824 — neuroscience — Posted on 2020-01-06

3295 Subcortical magnocellular visual system facilities object recognition by processing topological property

Wang, W.; Zhou, T.; Zhuo, Y.; Chen, L.; Huang, Y.

10.1101/2020.01.04.894725 — neuroscience — Posted on 2020-01-06

3296 Rapid contextualization of fragmented scene information in the human visual system

Kaiser, D.; Inciuraite, G.; Cichy, R. M.

10.1101/2020.01.06.895870 — neuroscience — Posted on 2020-01-06

3297 The complexity of model-free and model-based learning strategies

Filipowicz, A. L. S.; Levine, J.; Piasini, E.; Tavoni, G.; Kable, J. W.; Gold, J. I.

10.1101/2019.12.28.879965 — neuroscience — Posted on 2020-01-06

3298 Loss of vacuolar acidity results in iron sulfur cluster defects and divergent homeostatic responses during aging in Saccharomyces cerevisiae

Chen, K. L.; Ven, T. N.; Crane, M. M.; Brunner, M. L.; Pun, A. K.; Helget, K. L.; Brower, K.; Chen, D. E.; Doan, H.; Dillard-Telm, J. D.; Huynh, E.; Feng, Y.-C.; Yan, Z.; Golubeva, A.; Hsu, R. A.; Knight, R.; Levin, J.; Mobasher, V.; Muir, M.; Omokehinde, V.; Screws, C.; Tunali, E.; Tran, R. K.; Valdez, L.; Yang, E.; Kennedy, S. R.; Herr, A. J.; Kaeberlein, M.; Wasko, B. M.

10.1101/2020.01.05.895433 — molecular biology — Posted on 2020-01-06

3299 Characteristics of Titan cell formation vary across clinical isolates of Cryptococcus neoformans

Zhou, X.; Zafar, H.; Sephton-Clark, P. C. S.; Mohamed, S. H.; Drummond, R.; Dambuza, I. M.; Ballou, E.

10.1101/2020.01.03.894709 — microbiology — Posted on 2020-01-06

3300 Probabilistic gene expression signatures identify cell-types from single cell RNA-seq data

Grabski, I. N.; Irizarry, R. A.

10.1101/2020.01.05.895441 — genomics — Posted on 2020-01-06

3301 Modeling gene expression evolution with EvoGeneX uncovers differences in evolution of species, organs and sexes

Pal, S.; Oliver, B.; Przytycka, T. M.

10.1101/2020.01.06.895615 — evolutionary biology — Posted on 2020-01-06

3302 Calpain-2 regulates hypoxia/HIF-induced amoeboid reprogramming and metastasis

te Boekhorst, V.; Jiang, L.; Mahlen, M.; Meerlo, M.; Dunkel, G.; Durst, F. C.; Yang, Y.; Levine, H.; Burgering, B. M. T.; Friedl, P.

10.1101/2020.01.06.892497 — cancer biology — Posted on 2020-01-06

3303 GenomeChronicler: The Personal Genome Project UK Genomic Report Generator Pipeline

Guerra-Assuncao, J. A.; Conde, L.; Moghul, I.; Webster, A. P.; Ecker, S.; Chervova, O.; Chatzipantsiou, C.; Prieto, P. P.; Beck, S.; Herrero, J.

10.1101/2020.01.06.873026 — bioinformatics — Posted on 2020-01-06

3304 Low-cost microphysiological systems: Feasibility study of a tape-based barrier-on-chip system for small intestine modeling

Winkler, T. E.; Feil, M.; Stronkman, E. F.; Matthiesen, I.; Herland, A.

10.1101/2020.01.06.894147 — bioengineering — Posted on 2020-01-06

3305 miR-1290 stimulates proliferation of gastric cancer by targeting SP1 with overexpression of fucosyltransferase IV and α1, 3-fucosylated glycans

Aziz, f.; yulin, l.; Qiu, Y.

10.1101/2020.01.05.895300 — biochemistry — Posted on 2020-01-06

3306 Module analysis using single-patient differential expression signatures improve the power of association study for Alzheimer's disease

Huang, J.; Lu, D.; Meng, G.

10.1101/2020.01.05.894931 — genetics — Posted on 2020-01-06

3307 A sample preparation protocol for high throughput immunofluorescence of suspension cells

Backstrom, A.; Kugel, L.; Gnann, C.; Xu, H.; Aslan, J. E.; Lundberg, E.; Stadler, C.

10.1101/2020.01.05.895201 — cell biology — Posted on 2020-01-06

3308 Background reduction in STED-FCS using coherent-hybrid STED

Barbotin, A.; Urbancic, I.; Galiani, S.; Eggeling, C.; Booth, M.

10.1101/2020.01.06.895243 — biophysics — Posted on 2020-01-06

3309 Identifying Sequence Perturbations to an Intrinsically Disordered Protein that Determine Its Phase Separation Behavior

Schuster, B.; Dignon, G. L.; Tang, W. S.; Kelley, F.; Ranganath, A. K.; Jahnke, C. N.; Simpkins, A. G.; Regy, R. M.; Hammer, D. A.; Good, M. C.; Mittal, J.

10.1101/2020.01.06.894576 — biophysics — Posted on 2020-01-06

3310 Cryo-EM structures of the ATP release channel pannexin 1

Deng, Z.; He, Z.; Maksaev, G.; Bitter, R. M.; Rau, M.; Fitzpatrick, J. A. J.; Yuan, P.

10.1101/2020.01.05.895235 — biophysics — Posted on 2020-01-06

3311 Assessing the Quality of Cotranscriptional Folding Simulations

Kuehnl, F.; Stadler, P. F.; Findeiss, S.

10.1101/2020.01.06.895607 — bioinformatics — Posted on 2020-01-06

3312 Material-Driven Fibronectin Assembly Rescues Matrix Defects due to Mutations in Collagen IV in Fibroblasts

Mpoyi, E. N.; Cantini, M.; Sin, Y. Y.; Fleming, L.; Zhou, D. W.; Costell, M.; Lu, Y.; Kadler, K.; Garcia, A. J.; Van Agtmael, T.; Salmeron-Sanchez, M.

10.1101/2020.01.06.895839 — bioengineering — Posted on 2020-01-06

3313 ATP hydrolysis by the SNF2 domain of the ultraspecific maintenance methylase Dnmt5 drives recognition and modification of hemimethylated DNA

Dumesic, P. A.; Stoddard, C. I.; Catania, S.; Narlikar, G. J.; Madhani, H.

10.1101/2020.01.05.895227 — molecular biology — Posted on 2020-01-06

3314 Identification of NLR-associated amyloid signaling motifs in filamentous bacteria

Dyrka, W.; Coustou, V.; Daskalov, A.; Lends, A.; Bardin, T.; Berbon, M.; Kauffmann, B.; Blancard, C.; Salin, B.; Loquet, A.; Saupe, S. J.

10.1101/2020.01.06.895854 — microbiology — Posted on 2020-01-06

3315 Collective cell sorting requires contractile cortical waves in germline cells

Chanet, S.; Huynh, J.-R.

10.1101/2020.01.06.895847 — developmental biology — Posted on 2020-01-06

3316 Extracellular TGF-β downregulates the expression of Wnt transcription factor TCF7L2/TCF4 in mesenchymal stromal cells and fibroblasts

Contreras, O.; Soliman, H.; Theret, M.; Rossi, F. M.; Brandan, E.

10.1101/2020.01.05.895334 — cell biology — Posted on 2020-01-06

3317 Anti-tumor effects of an Id antagonist with no acquired resistance

Wojnarowicz, P. M.; Escalono, M. G.; Huang, Y.-H.; Desai, B.; Chin, Y.; Shah, R.; Xu, S.; Ouerfelli, O.; Soni, R. K.; Philip, J.; Montrose, D. C.; Healey, J. H.; Rajasekhar, V. K.; Garland, W. A.; Norton, L.; Rosen, N.; Hendrickson, R. C.; Zhou, X. K.; Iavarone, A.; Massague, J.; Dannenberg, A. J.; Lasorella, A.; Benezra, R.

10.1101/2020.01.06.894840 — cancer biology — Posted on 2020-01-06

3318 Prediction of synonymous corrections by the BE-FF computational tool expands the targeting scope of base editing

Rabinowitz, R.; Abadi, S.; Almog, S.; Offen, D.

10.1101/2020.01.06.890244 — bioinformatics — Posted on 2020-01-06

3319 ZEAMAP, a comprehensive database adapted to the maize multi-omics era

Gui, S.; Yang, L.; Li, J.; Luo, J.; Xu, X.; Yuan, J.; Chen, L.; Li, W.; Yang, X.; Wu, S.; Li, S.; Wang, Y.; Zhu, Y.; Gao, Q.; Yang, N.; Yan, J.

10.1101/2020.01.04.894626 — bioinformatics — Posted on 2020-01-06

3320 Fine Sieving of Collected Atmospheric Particles using Oil Electrophoresis (iSCAPE)

Li, X.; Xu, S.; Yao, M.

10.1101/2020.01.04.894998 — bioengineering — Posted on 2020-01-06

3321 Postglacial migration across a large dispersal barrier outpaces regional expansion from glacial refugia: evidence from two conifers in the Pacific Northwest.

Fernandez, M. C.; Hu, F. S.; Gavin, D. G.; deLafontaine, G.; Heath, K. D.

10.1101/2020.01.05.895193 — plant biology — Posted on 2020-01-06

3322 A deep dive into the ancestral chromosome number of flowering plants

Carta, A.; Bedini, G.; Peruzzi, L.

10.1101/2020.01.05.893859 — plant biology — Posted on 2020-01-06

3323 Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 in renal tubular cells

Matthews, O.; Morrison, E. E.; Tranter, J. D.; Starkey Lewis, P.; Toor, I.; Srivastava, A.; Sargeant, R.; Rollison, H.; Matchett, K. P.; Gray, G. A.; Goldring, C.; Park, K.; Denby, L.; Dhaun, N.; Bailey, M. A.; Henderson, N. C.; Williams, D.; Dear, J. W.

10.1101/2020.01.06.895821 — pharmacology and toxicology — Posted on 2020-01-06

3324 Coupling of translation quality control and mRNA targeting to stress granules

Moon, S. L.; Morisaki, T.; Stasevich, T. J.; Parker, R.

10.1101/2020.01.05.895342 — molecular biology — Posted on 2020-01-06

3325 Derived ecological niches of indoor microbes are crucial for asthma symptoms in university dormitories

Fu, X.; Li, Y.; Meng, Y.; Yuan, Q.; Zhang, Z.; Norback, D.; Deng, Y.; Zhang, X.; Sun, Y.

10.1101/2020.01.05.893529 — microbiology — Posted on 2020-01-06

3326 Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes

Paul, A. S.; Miliu, A.; Paulo, J. A.; Goldberg, J. M.; Bonilla, A. M.; Berry, L.; Seveno, M.; Braun-Breton, C.; Kosber, A. L.; Elsworth, B.; Arriola, J. S. N.; Lebrun, M.; Gygi, S. P.; Lamarque, M. H.; Duraisingh, M. T.

10.1101/2020.01.05.890483 — microbiology — Posted on 2020-01-06

3327 Genome-wide Functional Characterization of Escherichia coli Promoters and Regulatory Elements Responsible for their Function.

Urtecho, G.; Insigne, K.; Tripp, A. D.; Brinck, M.; Lubock, N. B.; Kim, H.; Chan, T.; Kosuri, S.

10.1101/2020.01.04.894907 — microbiology — Posted on 2020-01-06

3328 Spring phenology dominates over shade in affecting seedling performance and plant attack during the growing season

McClory, R. W.; van Dijk, L. J. A.; Mutz, J.; Ehrlen, J.; Tack, A. J. M.

10.1101/2020.01.05.895086 — ecology — Posted on 2020-01-06

3329 Alignment of single-cell RNA-seq samples without over-correction using kernel density matching

Chen, M.; Zhan, Q.; Mu, Z.; Wang, L.; Zheng, Z.; Miao, J.; Zhu, P.; Li, Y. I.

10.1101/2020.01.05.895136 — bioinformatics — Posted on 2020-01-06

3330 Mining the Selective Remodeling of DNA Methylation in Promoter Regions to Identify Robust Gene-Level Associations with Phenotype

Yuan, Q.; Liang, F.; Zhu, Y.; Chen, Y.; Xu, R.; Xiong, J.

10.1101/2020.01.05.895326 — bioinformatics — Posted on 2020-01-06

3331 Monitoring the production of high diffraction-quality crystals of two enzymes in real time using in situ dynamic light scattering

de Wijn, R.; Rollet, K.; Engilberge, S.; McEwen, A. G.; Hennig, O.; Betat, H.; Moerl, M.; Riobe, F.; Maury, O.; Girard, E.; Benas, P.; Lorber, B.; Sauter, C.

10.1101/2020.01.05.888370 — biochemistry — Posted on 2020-01-06

3332 Subpopulations of sensorless bacteria drive fitness in fluctuating environments

Julou, T.; Blank, D.; Fiori, A.; van Nimwegen, E.

10.1101/2020.01.04.894766 — systems biology — Posted on 2020-01-06

3333 1--4-phenylpiperazine Treatment After Brain Irradiation Preserves Cognitive Function in Mice

Bhat, K.; Medina, P.; He, L.; Zhang, L.; Saki, M.; Ioannidis, A.; Nguyen, N. T.; Sodhi, S. S.; Magyar, C. E.; Liau, L. M.; Kornblum, H.; Pajonk, F.

10.1101/2020.01.04.894865 — neuroscience — Posted on 2020-01-06

3334 Congruent population genetic structures and divergence histories in anther-smut fungi and their host plants Silene italica and the S. nutans species complex

Hartmann, F. E.; Snirc, A.; Cornille, A.; Gode, C.; Touzet, P.; Van Rossum, F.; Fournier, E.; Le Prieur, S.; Shykoff, J.; Giraud, T.

10.1101/2020.01.04.894774 — evolutionary biology — Posted on 2020-01-06

3335 High syphilis seropositivity in European brown hares, Lower Saxony, Germany

Hisgen, L.; Abel, L.; Hallmaier-Wacker, L. K.; Lueert, S.; Siebert, U.; Faehndrich, M.; Strauss, E.; Voigt, U.; Novakova, M.; Smajs, D.; Knauf, S.

10.1101/2020.01.05.893719 — ecology — Posted on 2020-01-06

3336 The landscape of mouse epididymal cells defined by the single-cell RNA-Seq

Shi, J.; Sang, M.; Xie, G.; Chen, H.

10.1101/2020.01.05.895052 — cell biology — Posted on 2020-01-06

3337 Optimizing immunization protocols to elicit broadly neutralizing antibodies

Sprenger, K. G.; Louveau, J. E.; Chakraborty, A. K.

10.1101/2020.01.04.894857 — biophysics — Posted on 2020-01-06

3338 Executable Simulation Model of the Liver

König, M.

10.1101/2020.01.04.894873 — systems biology — Posted on 2020-01-06

3339 Variation in the expression of a transmembrane protein influences cell growth in Arabidopsis thaliana petals by altering auxin availability.

Miller, C.; Dumenil, J.; Smith, C.; Lu, F.-H.; McKenzie, N.; Chapman, V.; Ball, J.; Bevan, M. W.

10.1101/2020.01.05.895078 — plant biology — Posted on 2020-01-06

3340 Contrasting adaptations to synaptic physiology of prefrontal cortex interneuron subtypes in a mouse model of binge drinking

Joffe, M. E.; Winder, D. G.; Conn, P. J.

10.1101/2020.01.05.895169 — neuroscience — Posted on 2020-01-06

3341 Low-Dimensional Spatio-Temporal Dynamics Underlie Cortex Wide Neural Activity

MacDowell, C. J.; Buschman, T. J.

10.1101/2020.01.05.895177 — neuroscience — Posted on 2020-01-06

3342 The mechanisms of in vivo commensal control of Clostridioides difficile virulence

Girinathan, B. P.; DiBenedetto, N.; Worley, J. N.; Peltier, J.; Lavin, R.; Delaney, M. L.; Cummins, C.; Onderdonk, A. B.; Gerber, G. K.; Dupuy, B.; Sonenshein, A. L.; Bry, L.

10.1101/2020.01.04.894915 — microbiology — Posted on 2020-01-06

3343 Cyano-assassins: Widespread cyanogenic production from cyanobacteria

Panou, M.; Gkelis, S.

10.1101/2020.01.04.894782 — microbiology — Posted on 2020-01-06

3344 An ExbD Disordered Domain Peptide Inhibits TonB System Activity

Kopp, D. R.; Postle, K.

10.1101/2020.01.05.895219 — microbiology — Posted on 2020-01-06

3345 Dense cellular segmentation using 2D-3D neural network ensembles for electron microscopy

Guay, M.; Emam, Z.; Anderson, A.; Aronova, M.; Leapman, R. D.

10.1101/2020.01.05.895003 — microbiology — Posted on 2020-01-06

3346 Development of a soft cell confiner to decipher the impact of mechanical stimuli on cells

Prunet, A.; Lefort, S.; Delanoe-Ayari, H.; Saci, S.; Simon, G.; Argoul, F.; Guyot, B.; Rieu, J.-P.; Gobert, S.; Maguer-Satta, V.; Riviere, C.

10.1101/2020.01.04.892695 — biophysics — Posted on 2020-01-06

3347 Robotic Stereotaxic System based on 3D skull reconstruction to improve surgical accuracy and speed

Ly, P. T.; Lucas, A.; Pun, S. H.; Dondzillo, A.; Liu, C.; Klug, A.; Lei, T.

10.1101/2020.01.04.894972 — bioengineering — Posted on 2020-01-06

3348 Biophysical basis of cellular multi-specificity encoded in a model molecular switch

Perica, T.; Mathy, C. J. P.; Xu, J.; Jang, G. M.; Zhang, Y.; Kaake, R.; Ollikainen, N.; Braberg, H.; Swaney, D. L.; Kelly, M. J. S.; Krogan, N. J.; Kortemme, T.

10.1101/2020.01.04.893909 — systems biology — Posted on 2020-01-06

3349 Alzheimer Disease Neuropathological Comorbidities Are Common in the Younger-Old

Beach, T. G.; Malek-Ahmadi, M.

10.1101/2020.01.03.894451 — neuroscience — Posted on 2020-01-06

3350 Electron Microscopic Reconstruction of Neural Circuitry in the Cochlea

Hua, Y.; Ding, X.; Wang, H.; Gao, Y.; Wang, F.; Moser, T.; Wu, H.

10.1101/2020.01.04.894816 — neuroscience — Posted on 2020-01-06

3351 Focal epilepsy modulates vesicular positioning at cortical synapses

Vannini, E.; Restani, L.; Dilillo, M.; McDonnell, L.; Caleo, M.; Marra, V.

10.1101/2020.01.05.895029 — neuroscience — Posted on 2020-01-06

3352 A Length Penalized Probabilistic Principal Curve Algorithm With Applications To Handwritten Digits And Pharmacologic Colon Imaging

Chen, H.; Weld, E.; Hendrix, C.; Caffo, B.

10.1101/2020.01.04.894964 — immunology — Posted on 2020-01-06

3353 Community structure and seasonality of bees and flowering plants in a riparian corridor of the lower Rio Grande River in Webb County, Texas (USA)

Rubio, A.; Longing, S.

10.1101/2020.01.04.894600 — ecology — Posted on 2020-01-06

3354 Bioethanol from Sago Waste Fermented by Baker's and Tapai Yeast as a Renewable Energy Source

Rijal, M.

10.1101/2020.01.03.894691 — developmental biology — Posted on 2020-01-06

3355 Thrombospondin-4 mediates hyperglycemia- and TGF-beta-induced inflammation in breast cancer

Muppala, S.; Xiao, R.; Gajeton, J.; Verbovetskiy, D.; Krukovets, I.; Stenina-Adognravi, O.

10.1101/2020.01.03.894436 — cancer biology — Posted on 2020-01-06

3356 The role of Fnr paralogs for controlling anaerobic metabolism in diazotroph Paenibacillus polymyxa WLY78

Shi, H.; Li, Y.; Hao, T.; Liu, X.; Zhao, X.; Chen, S.

10.1101/2020.01.03.894683 — microbiology — Posted on 2020-01-06

3357 Repetitive DNA profiles reveal evidence of rapid genome evolution and reflect species boundaries in ground beetles

Sproul, J. S.; Barton, L. M.; Maddison, D. R.

10.1101/2020.01.03.894527 — evolutionary biology — Posted on 2020-01-06

3358 Simultaneous Discovery of Positive and Negative Interactions Among Root Microbiome Bacteria Using Microwell Recovery Arrays

Barua, N.; Herken, A. M.; Stern, K. R.; Reese, S.; Powers, R. L.; Morrell-Falvey, J. L.; Platt, T. G.; Hansen, R. R.

10.1101/2020.01.03.894477 — bioengineering — Posted on 2020-01-06

3359 Mechanisms of spectrotemporal modulation detection for normal- and hearing-impaired listeners

Ponsot, E.; Varnet, L.; Wallaert, N.; Daoud, E.; Shamma, S. A.; Lorenzi, C.; Neri, P.

10.1101/2020.01.03.894667 — neuroscience — Posted on 2020-01-06

3360 A highly contiguous genome for the Golden-fronted Woodpecker (Melanerpes aurifrons) via a hybrid Oxford Nanopore and short read assembly

Wiley, G.; Miller, M. J.

10.1101/2020.01.03.894444 — genomics — Posted on 2020-01-06

3361 NetCombin: An algorithm for optimal level-k network construction from triplets

Poormohammadi, H.; Sardari Zarchi, M.

10.1101/2020.01.03.893743 — bioinformatics — Posted on 2020-01-06

3362 What matters to patients?: a timely question for Value Based Care

Hirpa, M.; Woreta, T.; Addis, H.; Kebede, S.

10.1101/2020.01.03.893826 — scientific communication and education — Posted on 2020-01-06

3363 An unorthodox mechanism underlying voltage sensitivity of TRPV1 ion channel

Yang, F.; Xu, L.; Lee, B. H.; Xiao, X.; Yarov-Yarovoy, V.; Zheng, J.

10.1101/2020.01.04.894980 — biophysics — Posted on 2020-01-06

3364 Genome sequencing of ion-beam-induced mutants facilitates the detection of candidate genes responsible for phenotypes of mutants in rice

Oono, Y.; Ichida, H.; Morita, R.; Nozawa, S.; Satoh, K.; Shimizu, A.; Abe, T.; Kato, H.; Hase, Y.

10.1101/666677 — plant biology — Posted on 2020-01-05

3365 Functionally distinct high and low theta oscillations in the human hippocampus

Goyal, A.; Miller, J.; Qasim, S.; Watrous, A. J.; Stein, J. M.; Inman, C. S.; Gross, R. E.; Willie, J. T.; Lega, B.; Lin, J.-J.; Sharan, A.; Wu, C.; Sperling, M. R.; Sheth, S. A.; McKhann, G. M.; Smith, E. H.; Schevon, C.; Jacobs, J.

10.1101/498055 — neuroscience — Posted on 2020-01-05

3366 Large-scale functional integration, rather than functional dissociation along dorsal and ventral streams, underlies visual perception and action

Ray, D.; Hajare, N.; Roy, D.; Banerjee, A.

10.1101/609487 — neuroscience — Posted on 2020-01-05

3367 Analysis of task-based functional MRI data preprocessed with fMRIPrep

Esteban, O.; Ciric, R.; Finc, K.; Blair, R. W.; Markiewicz, C. J.; Moodie, C. A.; Kent, J. D.; Goncalves, M.; DuPre, E.; Gomez, D. E.; Ye, Z.; Salo, T.; Valabregue, R.; Amlien, I. K.; Liem, F.; Jacoby, N.; Stojic, H.; Cieslak, M.; Urchs, S.; Halchenko, Y. O.; Ghosh, S. S.; de la Vega, A.; Yarkoni, T.; Wright, J. A.; Thompson, W. H.; Poldrack, R. A.; Gorgolewski, K. J.

10.1101/694364 — bioinformatics — Posted on 2020-01-05

3368 Chaperonin Abundance Boosts Bacterial Fitness

Kumar, S. C. M.; Chugh, K.; Dutta, A.; Mahamkali, V.; Bose, T.; Mande, S. S.; mande, s.; Lund, P. A.

10.1101/2019.12.31.891820 — biochemistry — Posted on 2020-01-05

3369 Designing signaling environments to steer transcriptional diversity in neural progenitor cell populations

Chen, S.; Thomson, M.; Park, J. H.; Tsou, T.; Rivaud, P.

10.1101/2019.12.30.890087 — systems biology — Posted on 2020-01-05

3370 Small-scale spatial structure influences large-scale invasion rates

Plank, M. J.; Simpson, M. J.; Binny, R. N.

10.1101/814582 — cell biology — Posted on 2020-01-05

3371 Layout symmetry facilitates spatial learning in the house cricket, Acheta domesticus, in the absence of visual cues

Baran, B.; Krzyzowski, M.; Radai, Z.; Francikowski, J.; Hohol, M.

10.1101/2019.12.28.886655 — animal behavior and cognition — Posted on 2020-01-05

3372 Harmonization of diffusion MRI datasets with adaptive dictionary learning

St-Jean, S.; Viergever, M. A.; Leemans, A.

10.1101/824706 — neuroscience — Posted on 2020-01-05

3373 Behavioral traits that define social dominance are the same that reduce social influence in a consensus task

Rodriguez-Santiago, M.; Nuehrenberg, P.; Derry, J.; Deussen, O.; Francisco, F.; Garrison, L. K.; Garza, S. F.; Hofmann, H.; Jordan, A. L.

10.1101/845628 — animal behavior and cognition — Posted on 2020-01-05

3374 Improved, scalable, two-stage, autoinduction of recombinant protein expression in E. coli utilizing phosphate depletion.

Menacho-Melgar, R.; Ye, Z.; Moreb, E. A.; Yang, T.; Efromson, J. P.; Decker, J. S.; Lynch, M. D.

10.1101/820787 — synthetic biology — Posted on 2020-01-05

3375 Revealing nonlinear neural decoding by analyzing choices

Yang, Q.; Walker, E. Y.; Cotton, R. J.; Tolias, A. S.; Pitkow, X. S.

10.1101/332353 — neuroscience — Posted on 2020-01-05

3376 Sequence and annotation of 42 cannabis genomes reveals extensive copy number variation in cannabinoid synthesis and pathogen resistance genes

McKernan, K. J.; Helbert, Y.; Kane, L. T.; Ebling, H.; Zhang, L.; Liu, B.; McLaughlin, S.; Eaton, Z.; Kingan, S. B.; Baybayan, P.; Concepcion, G.; Jordan, M.; Riva, A.; Barbazuk, B.; Harkins, T.

10.1101/2020.01.03.894428 — genomics — Posted on 2020-01-05

3377 CRISPR-based bioengineering of the Transferrin Receptor revealed a role for Rab7 in the biosynthetic secretory pathway

Deffieu, M.; Cesonyte, I.; Delalande, F.; Boncompain, G.; Dorobantu, C.; Song, E.; Lucansky, V.; Hirschler, A.; Cianferani, S.; Xu, T.; Perez, F.; Carapito, C.; Gaudin, R.

10.1101/2020.01.05.893206 — cell biology — Posted on 2020-01-05

3378 A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair

van den Heuvel, D.; Spruijt, C. G.; Gonzalez-Prieto, R.; Kragten, A.; Paulsen, M. T.; Zhou, D.; Wu, H.; Apelt, K.; van der Weegen, Y.; Yang, K.; Dijk, M.; Daxinger, L.; Marteijn, J. A.; Vertegaal, A. C. O.; Ljungman, M.; Vermeulen, M.; Luijsterburg, M. S.

10.1101/2020.01.04.894808 — cell biology — Posted on 2020-01-05

3379 Crystal and cryo-EM structures of the cytosolic G protein alpha chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1

McClelland, L. J.; Zhang, K.; Mou, T.-C.; Johnston, J.; Yates-Hansen, C.; li, S.; Thomas, C. J.; Doukov, T. I.; Triest, S.; Wohlkonig, A.; Tall, G. G.; Steyaert, J.; Chiu, W.; Sprang, S. R.

10.1101/2020.01.04.893156 — biochemistry — Posted on 2020-01-05

3380 NMR Line Shapes in Molecular Mechanisms with Ligand Binding and Multiple Conformers

Kovrigin, E. L.

10.1101/2020.01.03.894485 — biochemistry — Posted on 2020-01-05

3381 Engineering Cell-Permeable Proteins through Insertion of Cell-Penetrating Motifs into Surface Loops

Chen, K.; Pei, D.

10.1101/2020.01.03.894543 — biochemistry — Posted on 2020-01-05

3382 Estimating the effective sample size in association studies of quantitative traits

Ziyatdinov, A.; Kim, J.; Prokopenko, D.; Prive, F.; Laporte, F.; Loh, P.-R.; Kraft, P.; Aschard, H.

10.1101/2019.12.15.877217 — genetics — Posted on 2020-01-04

3383 Epigenetic regulation of Wnt7b expression by the cis-acting long noncoding RNA lnc-Rewind in muscle stem cells

Cipriano, A.; Macino, M.; Buonaiuto, G.; Santini, T.; Biferali, B.; Peruzzi, G.; Colantoni, A.; Mozzetta, C.; Ballarino, M.

10.1101/2020.01.03.894519 — cell biology — Posted on 2020-01-04

3384 Hypercholesterolemia Accelerates Both the Initiation and Progression of Angiotensin II-induced Abdominal Aortic Aneurysms

Liu, J.; Sawada, H.; Howatt, D. A.; Moorleghen, J. J.; Vsevolozhskaya, O.; Daugherty, A.; Lu, H. S.

10.1101/2020.01.03.893313 — pathology — Posted on 2020-01-04

3385 Insulin signaling mediates neurodegeneration in glioma

Jarabo, P.; de Pablo, C.; Herranz, H.; Martin, F. A.; Casas-Tinto, S.

10.1101/2020.01.03.894469 — neuroscience — Posted on 2020-01-04

3386 Dissociated hippocampal neurons exhibit distinct Zn2+ dynamics in a stimulation method-dependent manner

Sanford, L.; Palmer, A. E.

10.1101/2020.01.03.894501 — neuroscience — Posted on 2020-01-04

3387 Pathway-specific deregulation of striatal excitatory synapses in LRRK2 mutations

Chen, C.; Soto, G.; Bannon, N.; Kang, S.; Kozorovitskiy, Y.; Parisiadou, L.

10.1101/2020.01.03.894410 — neuroscience — Posted on 2020-01-04

3388 Environmental anchoring of grid-like representations minimizes spatial uncertainty during navigation

Navarro Schroeder, T.; Towse, B. W.; Nau, M.; Burgess, N.; Barry, C.; Doeller, C. F.

10.1101/166306 — neuroscience — Posted on 2020-01-04

3389 Structural and Functional Characterization of G Protein-Coupled Receptors with Deep Mutational Scanning

Jones, E. M.; Lubock, N. B.; Venkatakrishnan, A.; Wang, J.; Tseng, A. M.; Paggi, J. M.; Latorraca, N. R.; Cancilla, D.; Satyadi, M.; Davis, J.; Mohan, M. B.; Dror, R. O.; Kosuri, S.

10.1101/623108 — molecular biology — Posted on 2020-01-04

3390 An Arabidopsis long noncoding RNA modulates the transcriptome through interactions with a network of splicing factors

Rigo, R.; Bazin, J.; Romero-Barrios, N.; Moisson, M.; Lucero, L.; Christ, A.; Benhamed, M.; Blein, T.; Huguet, S.; Charon, C.; Crespi, M.; Ariel, F.

10.1101/2020.01.03.894055 — molecular biology — Posted on 2020-01-04

3391 Somatic selection of poorly differentiating variant stem cell clones could be a key to human ageing

Bodmer, W. F.; Crouch, D. J. M.

10.1101/797530 — cell biology — Posted on 2020-01-04

3392 Integrating NMR and Simulations Reveals Motions in the UUCG Tetraloop

Bottaro, S.; Nichols, P. J.; Vogeli, B.; Parrinello, M.; Lindorff-Larsen, K.

10.1101/690412 — biophysics — Posted on 2020-01-04

3393 Quantifying and engineering mucus adhesion of probiotics

Mays, Z. J. S.; Chappell, T. C.; Nair, N. U.

10.1101/731505 — bioengineering — Posted on 2020-01-04

3394 PulseDIA: in-depth data independent acquisition mass spectrometry using enhanced gas phase fractionation

Cai, X.; Ge, W.; Yi, X.; Sun, R.; Zhu, J.; Lu, C.; Sun, P.; Zhu, T.; Ruan, G.; Yuan, C.; Liang, S.; Lyu, M.; Huang, S.; Zhu, Y. J.; Guo, T.

10.1101/787705 — biochemistry — Posted on 2020-01-04

3395 Disruption of NAP1 genes supresses the fas1 mutant phenotype and enhances genome stability

Kolarova, K.; Nespor Dadejova, M.; Loja, T.; Sykorova, E.; Dvorackova, M.

10.1101/2020.01.03.894170 — molecular biology — Posted on 2020-01-04

3396 The highly expressed lipid buffer FABP4 enforces adipocyte cell identity by driving the initial cell differentiation process

Bahrami-Nejad, Z.; Chen, T.; Tholen, S.; Rabiee, A.; Zhao, M. L.; Bielczyk-Maczynska, E.; Teruel, M.

10.1101/2020.01.03.894493 — cell biology — Posted on 2020-01-03

3397 Cell-specific and targeted delivery of RNA moieties

Bhargava, A.; Ohara, P.; Jasmin, L.

10.1101/2020.01.03.893818 — neuroscience — Posted on 2020-01-03

3398 Epigenetic regulation of Wnt7b expression by the cis-acting long noncoding RNA lnc-Rewind in muscle stem cells

Cipriano, A.; Macino, M.; Buonaiuto, G.; Santini, T.; Biferali, B.; Peruzzi, G.; Colantoni, A.; Mozzetta, C.; Ballarino, M.

10.1101/2020.01.03.894519 — cell biology — Posted on 2020-01-03

3399 "Running with cancer": a qualitative study to evaluate barriers and motivations in running for female oncological patients.

Avancini, A.; Skroce, K.; Tregnago, D.; Frada, P.; Trestini, I.; Cercato, M. C.; Bonaiuto, C.; Tarperi, C.; Schena, F.; Milella, M.; Pilotto, S.; Lanza, M.

10.1101/2020.01.03.893792 — scientific communication and education — Posted on 2020-01-03

3400 Cytotoxic and mutagenic capacity of TTO and terpinen-4-ol in oral squamous cell carcinoma

Casalle, N.; de Andrade, C. R.

10.1101/2020.01.03.893735 — plant biology — Posted on 2020-01-03

3401 Therapeutic Efficacy and Safety of Lenvatinib for Unresectable Hepatocellular Carcinoma Beyond Progression with Sorafenib

Tomonari, T.; Sato, Y.; Tanaka, H.; Tanaka, T.; Fujino, Y.; Mitsui, Y.; Hirao, A.; Taniguchi, T.; Sogabe, M.; Okamoto, K.; Miyamoto, H.; Muguruma, N.; Kagiwada, H.; Kitazawa, M.; Fukui, K.; Horimoto, K.; Takayama, T.

10.1101/2020.01.03.893800 — molecular biology — Posted on 2020-01-03

3402 DNA damage induced during mitosis undergoes DNA repair synthesis

Gomez Godinez, V.; Kabbara, S.; Cohen, S.; Sherman, A.; Wu, T.; Kong, X.; Maravillas-Montero, J. L.; Shi, Z.; Preece, D.; Yokomori, K.; Berns, M.

10.1101/2020.01.03.893784 — cell biology — Posted on 2020-01-03

3403 Characterization of the Intestinal Absorption of Morroniside from Cornus officinalis Sieb. et Zucc via a Caco-2 Cell Monolayer Model

Xu, R.; Zhu, H.; Hu, L.; Yu, B.; Zhan, X.; Yuan, Y.; Zhou, P.

10.1101/2020.01.03.893768 — pharmacology and toxicology — Posted on 2020-01-03

3404 A long tail of truth and beauty: The developmental basis of complexity, symmetry, and beauty in the evolution of the peacocks tail.

Singh, R. S.; Jagadeeshan, S.

10.1101/2020.01.03.893776 — evolutionary biology — Posted on 2020-01-03

3405 A novel system to map protein interactions reveals evolutionarily conserved immune evasion pathways on transmissible cancers

Flies, A. S.; Darby, J. M.; Lennard, P. R.; Murphy, P. R.; Ong, C. E. B.; Pinfold, T. L.; Lyons, A. B.; Woods, G. M.; Patchett, A. L.

10.1101/831404 — immunology — Posted on 2020-01-03

3406 Neural evidence of recognition--but not recall--for videos in monkey hippocampus

Sakon, J. J.; Suzuki, W. A.

10.1101/2020.01.03.894394 — neuroscience — Posted on 2020-01-03

3407 Quantifying genetic effects on disease mediated by assayed gene expression levels

Yao, D. W.; O'Connor, L. J.; Price, A. L.; Gusev, A.

10.1101/730549 — genetics — Posted on 2020-01-03

3408 Quantifying accuracy and heterogeneity in single-molecule super-resolution microscopy

Mazidi, H.; Ding, T.; Nehorai, A.; Lew, M. D.

10.1101/721837 — biophysics — Posted on 2020-01-03

3409 Targeting the Pregnane X Receptor Using Microbial Metabolite Mimicry

Dvorak, Z.; Felix Kopp, F.; Costello, C. M.; Kemp, J. S.; Li, H.; Vrzalova, A.; Stepankova, M.; Iveta Bartonkov, I.; Poulikova, K.; Vyhlidalova, B.; Nordstroem, L. U.; Karunaratne, C.; Ranhotra, H.; Mun, K. S.; Naren, A. P.; Murray, I.; Perdew, G. H.; Brtko, J.; Toporova, L.; Schon, A.; Wallace, B.; Walton, W. G.; Redinbo, M. R.; Sun, K.; Beck, A.; Kortagere, S.; Neary, M. C.; Chandran, A.; Vishveshwara, S.; Cavalluzzi, M. M.; Lentini, G.; Cui, J. Y.; Gu, H.; March, J. C.; Chaterjee, S.; Matson, A.; Wright, D.; Flannigan, K. L.; Hirota, S. A.; Mani, S.; Sartor, R. B.

10.1101/792671 — biochemistry — Posted on 2020-01-03

3410 Analysis of task-based functional MRI data preprocessed with fMRIPrep

10.1101/694364 — bioinformatics — Posted on 2020-01-03

3411 ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells

Rodriguez, A. C.; Vahrenkamp, J. M.; Berrett, K. C.; Clark, K. A.; Guillen, K. P.; Scherer, S. D.; Yang, C.-H.; Welm, B. E.; Janat-Amsbury, M. M.; Graves, B. J.; Gertz, J.

10.1101/617142 — molecular biology — Posted on 2020-01-03

3412 A semi-automated machine learning-aided approach to quantitative analysis of centrosomes and microtubule organization

Sankaran, D. G.; Hariharan, B.; Pearson, C. G.

10.1101/2020.01.03.894071 — cell biology — Posted on 2020-01-03

3413 A versatile, multi-laser twin-microscope system for light-sheet imaging

Keomanee-Dizon, K.; Fraser, S. E.; Truong, T. V.

10.1101/801688 — biophysics — Posted on 2020-01-03

3414 Accurate reconstruction of the pan- and core- genomes of bacteria with PEPPA

Zhou, Z.; Achtman, M.

10.1101/2020.01.03.894154 — bioinformatics — Posted on 2020-01-03

3415 An Arabidopsis long noncoding RNA modulates the transcriptome through interactions with a network of splicing factors

Jeremie, B.; Rigo, R.; Romero-Barrios, N.; Moisson, M.; Lucero, L.; Christ, A.; Benhamed, M.; Blein, T.; Huguet, S.; Charon, C.; Crespi, M.; Ariel, F.

10.1101/2020.01.03.894055 — molecular biology — Posted on 2020-01-03

3416 Tools for the genetic manipulation of Herpetomonas muscarum

Sloan, M. A.; Ligoxygakis, P.

10.1101/2020.01.03.894162 — microbiology — Posted on 2020-01-03

3417 Opportunities for prioritizing and expanding conservation enterprise in India using carnivores as flagships

Srivathsa, A.; Majgaonkar, I.; Sharma, S.; Punjabi, G. A.; Singh, P.; Chawla, M. M.; Banerjee, A.

10.1101/2020.01.03.894311 — ecology — Posted on 2020-01-03

3418 Tree crowns as meeting points of diversity generating mechanisms - a test with epiphytic lichens in a temperate forest

Patzak, R.; Richter, R.; Engelmann, R.; Wirth, C.

10.1101/2020.01.03.894303 — ecology — Posted on 2020-01-03

3419 Programmable and portable CRISPR-Cas transcriptional activation in bacteria

Ho, H.-I.; Fang, J. R.; Cheung, J.; Wang, H. H.

10.1101/2020.01.03.882431 — synthetic biology — Posted on 2020-01-03

3420 Cloning and characterization of Osmotin (OsmSt) alleles from potato cultivar Kufri Chipsona 1

KAUR, A.; KUMAR, A.

10.1101/2020.01.03.894030 — plant biology — Posted on 2020-01-03

3421 A suppressor of axillary meristem maturation promotes longevity in flowering plants

Karami, O.; Rahimi, A.; Khan, M.; Bemer, M.; R. Hazarika, R.; Mak, P.; Compier, M.; van Noort, V.; Offringa, R.

10.1101/2020.01.03.893875 — plant biology — Posted on 2020-01-03

3422 Restoring the pattern of perineuronal net sulphation corrects age-related memory loss

Fawcett, J.; Gigout, S.; Molinari, A.; Naito-Matsui, Y.; Hilton, S.; Foscarin, S.; Nieuwenhuis, B.; Verhaagen, J.; Pizzorusso, T.; Saksida, L.; Bussey, T.; Kitagawa, H.; Kwok, J.

10.1101/2020.01.03.894188 — neuroscience — Posted on 2020-01-03

3423 Neural evidence of recognition--but not recall--for videos in monkey hippocampus

Sakon, J. J.; Suzuki, W. A.

10.1101/2020.01.03.894394 — neuroscience — Posted on 2020-01-03

3424 The stability flexibility tradeoff and the dark side of detail

Nassar, M. R.; Troiani, V.

10.1101/2020.01.03.894014 — neuroscience — Posted on 2020-01-03

3425 Dscam gene triplication causes neocortical overinhibition in Down syndrome

Liu, H.; Caballero-Floran, R. N.; Yang, T.; Hull, J. M.; Pan, G.; Li, R.; Veling, M. W.; Isom, L. L.; Kwan, K. Y.; Huang, Z. J.; Fuerst, P. G.; Jenkins, P. M.; Ye, B.

10.1101/2020.01.03.894113 — neuroscience — Posted on 2020-01-03

3426 Plasmodium falciparum population genetic complexity influences transcriptional profile and immune recognition of highly related genotypic clusters

Bei, A. K.; Larremore, D. B.; Miura, K.; Diouf, A.; Baro, N. K.; Daniels, R. F.; Griggs, A.; Moss, E. L.; Neafsey, D. E.; Deme, A. B.; Sy, M.; Schaffner, S.; Ahouidi, A. D.; Ndiaye, D.; Dieye, T.; Mboup, S.; Buckee, C. O.; Volkman, S. K.; Long, C. A.; Wirth, D. B.

10.1101/2020.01.03.894220 — microbiology — Posted on 2020-01-03

3427 Conditional Antibody Expression to Avoid Central B Cell Deletion in a Humanized HIV-1 Vaccine Mouse Models

Tian, M.; McGovern, K.; Cheng, H.-L.; Waddicor, P.; Rieble, L.; Kimble, M. T.; Dao, M.; Chen, Y.; Cantor, E.; Manfredonia, N.; Judson, R.; Chapdelaine-Williams, A.; Cain, D. W.; Haynes, B. F.; Alt, F. W.

10.1101/2020.01.03.894279 — immunology — Posted on 2020-01-03

3428 Genetic underpinnings of host manipulation by Ophiocordyceps as revealed by comparative transcriptomics

Will, I.; Das, B.; Trinh, T.; Brachmann, A.; Ohm, R. A.; de Bekker, C.

10.1101/2020.01.03.893917 — genomics — Posted on 2020-01-03

3429 Measuring historical and compositional signals in phylogenetic data

Jermiin, L. S.; Misof, B.

10.1101/2020.01.03.894097 — evolutionary biology — Posted on 2020-01-03

3430 Investigating TNS4 in the Colorectal Tumour Microenvironment Using 3D Spheroid Models of Invasion

Raposo, T. P.; Susanti, S.; Ilyas, M.

10.1101/2020.01.03.893958 — cancer biology — Posted on 2020-01-03

3431 The challenge of RNA branching prediction: a parametric analysis of multiloop initiation under thermodynamic optimization

Poznanovic, S.; Barrera-Cruz, F.; Kirkpatrick, A.; Ielusic, M.; Heitsch, C.

10.1101/2020.01.03.893891 — bioinformatics — Posted on 2020-01-03

3432 Mutational analysis of the structure and function of the chaperone domain of UNC-45B

Gaziova, I.; Moncrief, T.; Christian, C. J.; White, M. A.; Villarreal, M. A.; Powell, S.; Qadota, H.; Benian, G.; Oberhauser, A. F.

10.1101/2020.01.03.894048 — biophysics — Posted on 2020-01-03

3433 BEE : a web service for biomedical entity exploration

Jung, J.-u.; Lim, J.-M.; Joe, H.; Kim, H.-G.

10.1101/2020.01.03.893594 — bioinformatics — Posted on 2020-01-03

3434 PRIME: a probabilistic imputation method to reduce dropouteffects in single cell RNA sequencing

Jeong, H.; Liu, Z.

10.1101/2020.01.03.893867 — bioinformatics — Posted on 2020-01-03

3435 Bioengineering an in situ ovary (ISO) for fertility preservation

Buckenmeyer, M. J.; Sukhwani, M.; Iftikhar, A.; Nolfi, A. L.; Xian, Z.; Dadi, S.; Case, Z. W.; Steimer, S. R.; D'Amore, A.; Orwig, K. E.; Brown, B. N.

10.1101/2020.01.03.893941 — bioengineering — Posted on 2020-01-03

3436 Dual-localized enzymatic components that constitute the mitochondrial and plastidial fatty acid synthase systems

Guan, X.; Okazaki, Y.; Zhang, R.; Saito, K.; Nikolau, B. J.

10.1101/2020.01.03.894386 — biochemistry — Posted on 2020-01-03

3437 Cholesterol metabolism drives regulatory B cell function

Bibby, J. A.; Purvis, H. A.; Hayday, T.; Chandra, A.; Okkenhaug, K.; Wood, M.; Lachmann, H. J.; Kemper, C.; Cope, A.; Perucha, E.

10.1101/2020.01.03.893982 — immunology — Posted on 2020-01-03

3438 Consequences of combining life-history traits with sex-specific differences

Revathi Venkateswaran, V.; Roth, O.; Gokhale, C. S.

10.1101/2020.01.03.892810 — evolutionary biology — Posted on 2020-01-03

3439 Identification of a novel HIF-1α-αMβ2 Integrin-NETosis axis in fibrotic interstitial lung disease

Khawaja, A. A.; Chong, D. L. W.; Sahota, J.; Pericleous, C.; Ripoll, V. M.; Booth, H. L.; Khan, S.; Rodriguez-Justo, M.; Giles, I. P.; Porter, J. C.

10.1101/2020.01.03.894196 — immunology — Posted on 2020-01-03

3440 Predicting long-term multicategory cause of death in patients with prostate cancer: random forest versus multinomial model

Wang, J.; Deng, F.; Zeng, F.; Shanahan, A. J.; Zhang, L.

10.1101/2020.01.03.893966 — bioinformatics — Posted on 2020-01-03

3441 Improved Supra-Organization Is A Conformational And Functional Adaptation Of Respiratory Complexes

Rawat, S.; Ghosh, S.; Mondal, D.; Anusha, V.; Raychaudhuri, S.

10.1101/2020.01.03.892737 — biochemistry — Posted on 2020-01-03

3442 The Effect of Gelling agent, medium pH and silver nitrate on adventitious shoot regeneration in Solanum tuberosum

KAUR, A.; KUMAR, A.

10.1101/2020.01.03.894063 — plant biology — Posted on 2020-01-03

3443 Active outer hair cell motility can suppress vibrations in the organ of Corti

Nam, J.-H.; Jabeen, T.; Holt, J. C.; Becker, J.

10.1101/2020.01.03.893933 — neuroscience — Posted on 2020-01-03

3444 miR-206 knockout shows it is critical for myogenesis and directly regulates newly identified target mRNAs

Salant, G. M.; Tat, K. L.; Goodrich, J. A.; Kugel, J. F.

10.1101/2020.01.03.894246 — molecular biology — Posted on 2020-01-03

3445 cGAMP loading enhances the immunogenicity of VLP vaccines

Chauveau, L.; Bridgeman, A.; Tan, T. K.; Beveridge, R.; Frost, J.; Pedroza-Pacheco, I.; Partridge, T.; Borrow, P.; Drakesmith, H.; Townsend, A.; Rehwinkel, J.

10.1101/2020.01.03.893586 — immunology — Posted on 2020-01-03

3446 Accucopy: accurate and fast inference of allele-specific copy number alterations for heterogeneous tumor samples from high-throughput sequencing data

Fan, X.; Chen, L.; Liu, F.; Huang, Y.

10.1101/2020.01.02.892364 — bioinformatics — Posted on 2020-01-03

3447 Automatic building of protein atomic models from cryo-EM density maps using residue co-evolution

Bouvier, G.; Bardiaux, B.; Pellarin, R.; Rapisarda, C.; Nilges, M.

10.1101/2020.01.03.893669 — bioinformatics — Posted on 2020-01-03

3448 An Arabidopsis AT-hook motif nuclear protein mediates somatic embryogenesis and coinciding genome duplication

Karami, O.; Rahimi, A.; Mak, P.; Horstman, A.; Boutilier, K.; Compier, M.; van der Zaal, B.; Offringa, R.

10.1101/2020.01.03.892869 — plant biology — Posted on 2020-01-03

3449 Hypercholesterolemia Accelerates the Initiation and Progression of Angiotensin II-induced Abdominal Aortic Aneurysms

Liu, J.; Sawada, H.; Howatt, D. A.; Moorleghen, J. J.; Vsevolozhskaya, O.; Daugherty, A.; LU, H. S.

10.1101/2020.01.03.893313 — pathology — Posted on 2020-01-03

3450 The immediate early gene Arc is not required for hippocampal long-term potentiation.

Kyrke-Smith, M.; Volk, L. J.; Cooke, S. F.; Bear, M. F.; Huganir, R. L.; Shepherd, J. D.

10.1101/2020.01.03.893305 — neuroscience — Posted on 2020-01-03

3451 Interfering the mating of Chilo suppressalis (Walker): A new role of sex pheromones ((Z)-11-Octadecen-1-ol and (Z)-13 Octadecen-1-ol) from Cnaphalocrocis medinalis Guenee

Liang, Y.-y.; Luo, M.; Fu, X.-g.; Zheng, L.-x.; Wei, H.-y.

10.1101/2020.01.03.893339 — biochemistry — Posted on 2020-01-03

3452 DNA methylation across the genome in aged human skeletal muscle tissue and muscle stem cells: The role of HOX genes and physical activity

Turner, D. C.; Gorski, P. P.; Maasar, M. F.; Seaborne, R. A.; Baumert, P.; Brown, A. D.; Kitchen, M. O.; Erskine, R. M.; Dos-Remedios, I.; Voisin, S.; Eynon, N.; Sultanov, R. I.; Borisov, O. V.; Larin, A. K.; Semenova, E. A.; Popov, D. V.; Generozov, E. V.; Stewart, C. E.; Drust, B.; Owens, D. J.; Ahmetov, I. I.; Sharples, A. P.

10.1101/2019.12.27.886135 — physiology — Posted on 2020-01-03

3453 Distinct cellular mediators drive the Janus Faces of Toll-like Receptor 4 regulation of network excitability which impacts working memory performance after brain Injury

Korgaonkar, A. A.; Li, Y.; Guevarra, J.; Pang, K. C.; Santhakumar, V.; Nguyen, S.

10.1101/750869 — neuroscience — Posted on 2020-01-03

3454 Rapid acquisition of near optimal stopping using Bayesian by-products

Calder-Travis, J.; Slade, E.

10.1101/844969 — neuroscience — Posted on 2020-01-03

3455 Perceptual decisions are biased toward relevant prior choices

Feigin, H.; Baror, S.; Bar, M.; Zaidel, A.

10.1101/858324 — neuroscience — Posted on 2020-01-03

3456 Prioritized neural computations of socially-relevant signals during perceptual decision-making

Meaux, E.; El Zein, M.; Mennella, R.; Wyart, V.; Grezes, J.

10.1101/859942 — neuroscience — Posted on 2020-01-03

3457 Pyk2 Overexpression in Postsynaptic Neurons Blocks Aβ1-42-induced Synaptotoxicity in a Microfluidic Co-Culture Model

Kilinc, D.; Vreulx, A.-C.; Mendes, T.; Flaig, A.; Verschoore, M.; Demiautte, F.; Amouyel, P.; Eysert, F.; Dourlen, P.; Chapuis, J.; Malmanche, N.; Checler, F.; Lambert, J.-C.

10.1101/2019.12.20.884205 — neuroscience — Posted on 2020-01-03

3458 Adenosine signaling and its downstream target mod(mdg4) modify the pathogenic effects of polyglutamine in a Drosophila model of Huntington's disease

Lin, Y.-H.; Ouns Maaroufi, H.; Kucerova, L.; Rouhova, L.; Filips, T.; Zurovec, M.

10.1101/2019.12.22.886143 — genetics — Posted on 2020-01-03

3459 Quantifying the dynamics of pig movements improves targeted disease surveillance and control plans

Machado, G.; Galvis, J. A.; Lopes, F. P. N.; Voges, J.; Medeiros, A. A. R.; Cardenas, N.

10.1101/2019.12.29.886408 — ecology — Posted on 2020-01-03

3460 The SAMPL6 SAMPLing challenge: Assessing the reliability and efficiency of binding free energy calculations

Rizzi, A.; Jensen, T.; Slochower, D. R.; Aldeghi, M.; Gapsys, V.; Ntekoumes, D.; Bosisio, S.; Papadourakis, M.; Henriksen, N. M.; de Groot, B. L.; Cournia, Z.; Dickson, A.; Michel, J.; Gilson, M. K.; Shirts, M. R.; Mobley, D. L.; Chodera, J. D.

10.1101/795005 — biophysics — Posted on 2020-01-03

3461 Adhesion force spectroscopy with nanostructured colloidal probes reveals nanotopography-dependent early mechanotransductive interactions at the cell membrane level

Chighizola, M.; Previdi, A.; Dini, T.; Piazzoni, C.; Lenardi, C.; Milani, P.; Schulte, C.; Podesta', A.

10.1101/2020.01.02.892919 — biophysics — Posted on 2020-01-03

3462 Type I interferon responses to ischemic injury begin in the bone marrow of mice and humans and depend on Tet2, Nrf2, and Irf3

Calcagno, D. M.; Ng, R.; Toomu, A.; Zhang, C.; Huang, K.; Aguirre, A.; Weissleder, R.; Daniels, L.; Fu, Z.; King, K.

10.1101/765404 — immunology — Posted on 2020-01-03

3463 Self-supervised retinal thickness prediction enables deep learning from unlabeled data to boost classification of diabetic retinopathy

Holmberg, O. G.; Koehler, N. D.; Martins, T.; Siedlecki, J.; Herold, T.; Keidel, L. F.; Asani, B.; Schiefelbein, J.; Priglinger, S.; Kortuem, K.; Theis, F. J.

10.1101/861757 — bioinformatics — Posted on 2020-01-03

3464 Dynamic evolution of euchromatic satellites on the X chromosome in Drosophila melanogaster and the simulans clade

Sproul, J. S.; Khost, D. E.; Eickbush, D. G.; Negm, S.; Wei, X.; Wong, I.; Larracuente, A. M.

10.1101/846238 — genomics — Posted on 2020-01-03

3465 Testosterone-mediated behavior shapes the emergent properties of social networks

Dakin, R.; Moore, I. T.; Horton, B. M.; Vernasco, B. J.; Ryder, T. B.

10.1101/737650 — animal behavior and cognition — Posted on 2020-01-03

3466 Ant collective behavior is heritable and shaped by selection

Walsh, J. T.; Garnier, S.; Linksvayer, T. A.

10.1101/567503 — evolutionary biology — Posted on 2020-01-03

3467 Assessing seasonal demographic covariation to understand environmental-change impacts on a hibernating mammal

Paniw, M.; Childs, D.; Armitage, K. B.; Blumstein, D. T.; Martin, J.; Oli, M.; Ozgul, A.

10.1101/745620 — ecology — Posted on 2020-01-03

3468 Indication of a reduction in the cover of thin-leaved plants in Danish grasslands over an eight-year period

Damgaard, C.

10.1101/735472 — ecology — Posted on 2020-01-03

3469 Characterization of the Intestinal Absorption of Morroniside from Cornus officinalis Sieb. et Zucc via a Caco-2 Cell Monolayer Model

Xu, R.; Zhu, H.; Hu, L.; Yu, B.; Zhan, X.; Yuan, Y.; Zhou, P.

10.1101/2020.01.03.893768 — pharmacology and toxicology — Posted on 2020-01-03

3470 Therapeutic Efficacy and Safety of Lenvatinib for Unresectable Hepatocellular Carcinoma Beyond Progression with Sorafenib

10.1101/2020.01.03.893800 — molecular biology — Posted on 2020-01-03

3471 "Running with cancer": a qualitative study to evaluate barriers and motivations in running for female oncological patients.

Avancini, A.; Skroce, K.; Tregnago, D.; Frada, P.; Trestini, I.; Cercato, M. C.; Bonaiuto, C.; Tarperi, C.; Schena, F.; Milella, M.; Pilotto, S.; Lanza, M.

10.1101/2020.01.03.893792 — scientific communication and education — Posted on 2020-01-03

3472 Cytotoxic and mutagenic capacity of TTO and terpinen-4-ol in oral squamous cell carcinoma

Casalle, N.; de Andrade, C. R.

10.1101/2020.01.03.893735 — plant biology — Posted on 2020-01-03

3473 Identification of Reptarenaviruses, Hartmaniviruses and a Novel Chuvirus in Captive Brazilian Native Boa Constrictors with Boid Inclusion Body Disease

Argenta, F. F.; Hepojoki, J.; Smura, T.; Szirovicza, L.; Hammerschmitt, M. E.; Driemeier, D.; Kipar, A.; Hetzel, U.

10.1101/2020.01.02.893420 — microbiology — Posted on 2020-01-03

3474 A long tail of truth and beauty: The developmental basis of complexity, symmetry, and beauty in the evolution of the peacocks tail.

Singh, R. S.; Jagadeeshan, S.

10.1101/2020.01.03.893776 — evolutionary biology — Posted on 2020-01-03

3475 Proposed model of the Dictyostelium cAMP receptors bound to cAMP

Greenhalgh, J. C.; Chandran, A.; Harper, M. T.; Ladds, G.; Rahman, T.

10.1101/694810 — biochemistry — Posted on 2020-01-03

3476 Tracking activity patterns of a multispecies community of gymnotiform weakly electric fish in their neotropical habitat

Henninger, J.; Sinz, F.; Krahe, R.; Benda, J.

10.1101/550814 — animal behavior and cognition — Posted on 2020-01-03

3477 Human Inference in Changing Environments with TemporalStructure

Prat-Carrabin, A.; Wilson, R. C.; Cohen, J. D.; Azeredo da Silveira, R.

10.1101/720516 — neuroscience — Posted on 2020-01-03

3478 Arl13b regulates Sonic Hedgehog signaling from outside primary cilia

Gigante, E. D.; Taylor, M. R.; Ivanova, A. A.; Kahn, R. A.; Caspary, T.

10.1101/711671 — developmental biology — Posted on 2020-01-03

3479 Inhibition stabilization is a widespread property of cortical networks

Sanzeni, A. H.; Akitake, B.; Goldbach, H. C.; Leedy, C. E.; Brunel, N.; Histed, M. H.

10.1101/656710 — neuroscience — Posted on 2020-01-03

3480 In vivo electrophysiological validation of DREADD-based inhibition of pallidal neurons in the non-human primate.

Deffains, M.; Nguyen, T.-H.; Orignac, H.; Biendon, N.; Dovero, S.; Bezard, E.; Boraud, T.

10.1101/2020.01.03.893610 — neuroscience — Posted on 2020-01-03

3481 Signed Reward Prediction Errors in the Ventral Striatum Drive Episodic Memory

Calderon, C. B.; De Loof, E.; Ergo, K.; Snoeck, A.; Boehler, C. N.; Verguts, T.

10.1101/2020.01.03.893578 — neuroscience — Posted on 2020-01-03

3482 ERCC1-XPF Interacts with Topoisomerase IIβ to Facilitate the Repair of Activity-induced DNA Breaks

Chatzinikolaou, G.; Stratigi, K.; Agathangelou, K.; Tsekrekou, M.; Goulielmaki, E.; Chatzidoukaki, O.; Gkirtzimanaki, K.; Aid-Pavlidis, T.; Aivaliotis, M.; Pavlidis, P.; Tsamardinos, I.; Topalis, P.; Bouwman, B. A. M.; Crosetto, N.; Altmueller, J.; Garinis, G. A.

10.1101/2020.01.03.892703 — genetics — Posted on 2020-01-03

3483 Inhibition of DNAJ-HSP70 interaction improves strength in muscular dystrophy

Bengoechea, R.; Findlay, A. R.; Bhadra, A.; Shao, H.; Stein, K.; Pittman, S. K.; Daw, J.; Gestwicki, J.; True, H.; Weihl, C. C.

10.1101/2020.01.03.893149 — cell biology — Posted on 2020-01-03

3484 Host-induced silencing of the Colletotrichum gloeosporioides conidial morphology 1 gene (CgCOM1) confers resistance against Anthracnose disease in chilli and tomato

Mahto, B. K.; Singh, A.; Pareek, M.; Rajam, M. V.; Dhar-Ray, S.; Reddy, P. M.

10.1101/2020.01.03.893677 — plant biology — Posted on 2020-01-03

3485 Chop/Ddit3 depletion in β-cells alleviates ER stress and corrects hepatic steatosis

Yong, J.; Parekh, V. P.; Nayak, J.; Chen, Z.; Lebeaupin, C.; Zhang, J.; Prakash, T. P.; Murray, S.; Guo, S.; Ayala, J. E.; Satin, L. S.; Kaufman, R. J.

10.1101/2020.01.02.893271 — physiology — Posted on 2020-01-03

3486 Cellular identity and Ca2+ signaling activity of the non-reproductive GnRH system in the Ciona larva

Okawa, N.; Shimai, K.; Ohnishi, K.; Ohkura, M.; Nakai, J.; Horie, T.; Kuhara, A.; Kusakabe, T. G.

10.1101/2020.01.02.893354 — neuroscience — Posted on 2020-01-03

3487 VolPy: automated and scalable analysis pipelines for voltage imaging datasets

Cai, C.; Friedrich, J.; Pnevmatikakis, E. A.; Podgorski, K.; Giovannucci, A.

10.1101/2020.01.02.892323 — neuroscience — Posted on 2020-01-03

3488 A general role of zinc binding domain revealed by structures of σ28-dependent transcribing complexes

Shi, W.; Zhou, W.; Zhang, B.; Huang, S.; Jiang, Y.; Schammel, A.; Hu, Y.; Liu, B.

10.1101/2020.01.02.893370 — molecular biology — Posted on 2020-01-03

3489 Optimization of subsampling, decontamination, and DNA extraction of difficult peat and silt permafrost samples

Saidi-Mehrabad, A.; Neuberger, P.; Cavaco, M.; Froese, D.; Lanoil, B. D.

10.1101/2020.01.02.893438 — microbiology — Posted on 2020-01-03

3490 A novel toxin-antitoxin module SlvT-SlvA governs megaplasmid stability and incites solvent tolerance in Pseudomonas putida S12

Kusumawardhani, H.; van Dijk, D.; Hosseini, R.; de Winde, J. H.

10.1101/2020.01.02.893495 — microbiology — Posted on 2020-01-03

3491 Improving the informativeness of Mendelian disease pathogenicity scores for common disease

Kim, S. S.; Dey, K. K.; Weissbrod, O.; Marquez-Luna, C.; Gazal, S.; Price, A. L.

10.1101/2020.01.02.890657 — genetics — Posted on 2020-01-03

3492 Termination of non-coding transcription in yeast relies on both a CTD-interaction domain and a CTD-mimic in Sen1

Han, Z.; Jasnovidova, O.; Haidara, N.; Tudek, A.; Kubicek, K.; Libri, D.; Stefl, R.; Porrua, O.

10.1101/433045 — genetics — Posted on 2020-01-03

3493 Explaining the effects of distractor statistics in visual search

Calder-Travis, J.; Ma, W. J.

10.1101/2020.01.03.893057 — animal behavior and cognition — Posted on 2020-01-03

3494 To Group or not to group: Group size dynamics and intestinal parasites in Indian peafowl populations

Dange, P.; Mhaisalkar, P.; Paranjpe, D.

10.1101/2020.01.03.893503 — ecology — Posted on 2020-01-03

3495 Chamaeleo: a robust library for DNA storage coding schemes

Ping, Z.; Zhang, H.; Chen, S.; Zhuang, Q.; Zhu, S.; Shen, Y.

10.1101/2020.01.02.892588 — bioinformatics — Posted on 2020-01-03

3496 Community lifespan, niche expansion and the evolution of interspecific cooperation

Rodrigues, A. M. M.; Estrela, S.; Brown, S. P.

10.1101/2020.01.02.893321 — evolutionary biology — Posted on 2020-01-03

3497 Inferring transmission bottleneck size from viral sequence data using a novel haplotype reconstruction method

Ghafari, M.; Lumby, C. K.; Weissman, D.; Illingworth, C. J. R.

10.1101/2020.01.03.891242 — evolutionary biology — Posted on 2020-01-03

3498 Reduction of Elevated Proton Leak Rejuvenates Mitochondria in the Aged Cardiomyocyte

Zhang, H.; Alder, N. N.; Wang, W.; Szeto, H.; Marcinek, D. J.; Rabinovitch, P. S.

10.1101/2020.01.02.893362 — cell biology — Posted on 2020-01-03

3499 Small non-coding RNA CjNC110 influences motility, autoagglutination, AI-2 localization, and chicken colonization in Campylobacter jejuni

Kreuder, A. J.; Ruddell, B.; Mou, K.; Hassall, A.; Zhang, Q.; Plummer, P. J.

10.1101/2020.01.02.893479 — microbiology — Posted on 2020-01-03

3500 Improved subspecies identification in clinical Mycobacterium abscessus complex isolates using whole genome sequence

Lin, D.; Sun, R.; Tan, Y.; Wang, J.; Chen, X.

10.1101/2020.01.02.893412 — microbiology — Posted on 2020-01-03

3501 In Vitro Probiotic Potential of Hemophilin-producing Strains of Haemophilus haemolyticus

Atto, B. A.; Latham, R.; Kunde, D.; Gell, D.; Tristram, S.

10.1101/2020.01.02.893487 — microbiology — Posted on 2020-01-03

3502 The Gut Microbiome of the Eastern Spruce Budworm Does Not Influence Larval Growth or Survival

Schwarz, M. T.; Kneeshaw, D.; Kembel, S. W.

10.1101/330928 — microbiology — Posted on 2020-01-03

3503 Aging dampens the intestinal innate immune response during Clostridioides difficile infection and is associated with altered intestinal eosinophil mobilization

Abernathy-Close, L.; Dieterle, M. G.; Vendrov, K. C.; Bergin, I. L.; Young, V. B.

10.1101/2020.01.02.893461 — immunology — Posted on 2020-01-03

3504 Temporal and spatial changes in phyllosphere microbiome of acacia trees growing in super arid environments

Al Ashhab, A.; Meshner, S.; Alexander-Shani, R.; Brandwein, M.; Bar Lavan, Y.; Winters, G.

10.1101/2020.01.02.893446 — ecology — Posted on 2020-01-03

3505 The roles of wrinkle structures in the veins of Asian Ladybird and bioinspiration

Song, Z.; Yan, Y.; Wu, W.; Tong, J.; sun, j.

10.1101/2020.01.02.893388 — biophysics — Posted on 2020-01-03

3506 The transcriptional landscape of cultivated strawberry (Fragraia x ananassa) and its diploid ancestor (Fragraia x vesca) during fruit development

Li, Y.; Liu, S.; Liu, T.; Luo, H.

10.1101/2020.01.02.893453 — plant biology — Posted on 2020-01-03

3507 Flattened circadian glucocorticoid oscillations cause obesity due to increased lipid turnover and lipid uptake

Tholen, S.; Kovary, K. M.; Rabiee, A.; Bielczyk-Maczynska, E.; Yang, W.; Teruel, M.

10.1101/2020.01.02.893081 — physiology — Posted on 2020-01-03

3508 Disputing space-based biases in unilateral complex regional pain syndrome

Halicka, M.; Vitterso, A. D.; McCullough, H.; Goebel, A.; Heelas, L.; Proulx, M. J.; Bultitude, J. H.

10.1101/2020.01.02.893263 — neuroscience — Posted on 2020-01-03

3509 Cortical 6-9 Hz Oscillation are a Reliable Biomarker of Persistent Pain in Rats

Furman, A. J.; Raver, C.; Li, Y.; Jenne, C.; Hoffman, K.; Seminowicz, D.; Keller, A.

10.1101/2020.01.02.893289 — neuroscience — Posted on 2020-01-03

3510 MetaConnect, a new platform for population viability modelling to assist decision makers in conservation and urban planning

Moulherat, S.; Bestion, E.; Baguette, M.; Moulherat, M.; Palmer, S. C. F.; Travis, J. M.; Clobert, J.

10.1101/2019.12.30.890921 — ecology — Posted on 2020-01-03

3511 Ectopic overexpression of abiotic stress-induced rice annexin, OsAnn5 potentiates tolerance to abiotic stresses

Boyidi, P.; Vikas, T. S.; Botta, H. K.; Yadav, D.; Pulugurtha, B. K.

10.1101/2019.12.16.869131 — plant biology — Posted on 2020-01-02

3512 Brain-Score: Which Artificial Neural Network for Object Recognition is most Brain-Like?

Schrimpf, M.; Kubilius, J.; Hong, H.; Majaj, N. J.; Rajalingham, R.; Issa, E. B.; Kar, K.; Bashivan, P.; Prescott-Roy, J.; Geiger, F.; Schmidt, K.; Yamins, D. L. K.; DiCarlo, J. J.

10.1101/407007 — neuroscience — Posted on 2020-01-02

3513 Multi-trait random regression models increase genomic prediction accuracy for a temporal physiological trait derived from high-throughput phenotyping

Baba, T.; Momen, M.; Campbell, M. T.; Walia, H.; Morota, G.

10.1101/772038 — genetics — Posted on 2020-01-02

3514 Intra- and Inter-Specific Investigations of Skeletal DNA Methylation and Femur Morphology in Primates

Housman, G.; Quillen, E. E.; Stone, A. C.

10.1101/554618 — genomics — Posted on 2020-01-02

3515 A plug and play microfluidic platform for standardized sensitive low-input Chromatin Immunoprecipitation

Dirks, R. A. M.; Thomas, P.; Jones, R. C.; Stunnenberg, H. G.; Marks, H.

10.1101/2020.01.02.893180 — genetics — Posted on 2020-01-02

3516 Structural colours reflect individual quality: a meta-analysis

White, T. E.

10.1101/2020.01.01.892547 — evolutionary biology — Posted on 2020-01-02

3517 Neural circuit mechanism underlying the feeding controlled by insula-central amygdala pathway

Zhang-Molina, C.; Schmit, M. B.; Cai, H.

10.1101/750562 — neuroscience — Posted on 2020-01-02

3518 Near-chromosome level genome assembly of the fruit pest Drosophila suzukii using long-read sequencing

Paris, M.; Boyer, R.; Jaenichen, R.; Wolf, J. B. W.; Karageorgi, M.; Green, J.; Cagnon, M.; Parinello, H.; Estoup, A.; Gautier, M.; Gompel, N.; Prud'homme, B.

10.1101/2020.01.02.892844 — ecology — Posted on 2020-01-02

3519 Integrative computational approach identifies new targets in CD4+ T cell-mediated immune disorders

Puniya, B. L.; Lichter, B.; Moore, R.; Ciurej, A.; Townsend, S.; Shah, A. R.; Barberis, M.; Helikar, T.

10.1101/2020.01.02.893164 — systems biology — Posted on 2020-01-02

3520 Human Genes Are In Silico Potential Targets For Rice miRNA

Ivashchenko, A.; Rakhmetullina, A.; Pyrkova, A.; Aisina, D.

10.1101/2020.01.02.893040 — plant biology — Posted on 2020-01-02

3521 The Arabidopsis N-terminal Acetyltransferase NAA50 Regulates Plant Growth and Defense

Neubauer, M.; Innes, R. W.

10.1101/2020.01.02.893115 — plant biology — Posted on 2020-01-02

3522 CXCR4-binding PET tracers link monocyte recruitment and endothelial injury in murine atherosclerosis

Randolph, G. J.; Elvington, A.; Baba, O.; Sultan, D.; Heo, G. S.; Zhang, X.; Luehmann, H.; Detering, L.; Szpakowska, M.; Chevigne, A.; Liu, Y.

10.1101/2020.01.02.892935 — pathology — Posted on 2020-01-02

3523 Light Sheet Fluorescence Microscopy as a New Method for Unbiased Three-Dimensional Analysis of Vascular Injury

Buglak, N. E.; Lucitti, J.; Ariel, P.; Maiocchi, S.; Miller, F. J.; Bahnson, E. M.

10.1101/2020.01.02.893065 — pathology — Posted on 2020-01-02

3524 EZcalcium: Open Source Toolbox for Analysis of Calcium Imaging Data

Cantu, D. A.; Wang, B.; Gongwer, M. W.; He, C. X.; Goel, A.; Suresh, A.; Kourdougli, N.; Arroyo, E. D.; Zeiger, W.; Portera-Cailliau, C.

10.1101/2020.01.02.893198 — neuroscience — Posted on 2020-01-02

3525 Effects of language experience on domain-general perceptual strategies

Jasmin, K.; Sun, H.; Tierney, A. T.

10.1101/2020.01.02.892943 — neuroscience — Posted on 2020-01-02

3526 Non-canonical glutamate signaling in a genetic model of migraine with aura

Parker, P. D.; Suryavanshi, P.; Melone, M.; Reinhart, K. M.; Sawant-Pokam, P. M.; Kaufmann, D.; Theriot, J. J.; Pugliese, A.; Conti, F.; Shuttleworth, C. W.; Pietrobon, D.; Brennan, K.

10.1101/2020.01.02.891770 — neuroscience — Posted on 2020-01-02

3527 Encoding of reinforcement along the hippocampal long axis and the transition from exploration to exploitation

Dombrovski, A. Y.; Luna, B.; Hallquist, M. N.

10.1101/2020.01.02.893255 — neuroscience — Posted on 2020-01-02

3528 Complex interactions between weather, and microbial and physiochemical water quality impact the likelihood of detecting foodborne pathogens in agricultural water

Weller, D. L.; Brassill, N.; Rock, C.; Ivanek, R.; Mudrak, E.; Roof, S.; Ganda, E.; Wiedmann, M.

10.1101/2020.01.02.892851 — microbiology — Posted on 2020-01-02

3529 LocusFocus: A web-based colocalization tool for the annotation and functional follow-up of GWAS

Panjwani, N.; Wang, F.; Wang, C.; He, G.; Mastromatteo, S.; Bao, A.; Gong, J.; Rommens, J. M.; Sun, L.; Strug, L. J.

10.1101/2020.01.02.891291 — genomics — Posted on 2020-01-02

3530 Three previously characterized resistances to yellow rust are encoded by a single locus Wtk1

Klymiuk, V.; Fatiukha, A.; Raats, D.; Bocharova, V.; Huang, L.; Feng, L.; Jaiwar, S.; Pozniak, C.; Coaker, G.; Dubcovsky, J.; Fahima, T.

10.1101/2020.01.02.892968 — genetics — Posted on 2020-01-02

3531 Dutch population structure across space, time and GWAS design

Byrne, R. P.; van Rheenen, W.; Project MinE ALS GWAS Consortium, ; van den Berg, L. H.; Veldink, J. H.; McLaughlin, R. L.

10.1101/2020.01.01.892513 — genetics — Posted on 2020-01-02

3532 Estimating invasion dynamics with geopolitical-unit level records: performance and similarity of common methods using both simulated data and a real case

Liang, W.; Tran, L.; Wiggins, G.; Grant, J.

10.1101/2020.01.02.893248 — ecology — Posted on 2020-01-02

3533 Label-free three-dimensional observations and quantitative characterisation of on-chip vasculogenesis using optical diffraction tomography

Lee, C.; Kim, S.; Hugonnet, H.; Lee, M.; Park, W.; Jeon, J.; Park, Y.

10.1101/2020.01.01.892620 — bioengineering — Posted on 2020-01-02

3534 Interleukin-22 drives a metabolic adaptive reprogramming to maintain mitochondrial fitness and treat liver injury

Chen, W.; Zai, W.; Fan, J.; Zhang, X.; Luan, J.; Wang, Y.; Shen, Y.; Wang, Z.; Dai, S.; Fang, S.; Ju, D.

10.1101/2020.01.02.892927 — biochemistry — Posted on 2020-01-02

3535 Structure-function analysis of interallelic complementation in ROOTY transheterozygotes

Brumos, J.; Bobay, B. G.; Clark, C. A.; Alonso, J. M.; Stepanova, A. N.

10.1101/2020.01.02.893016 — genetics — Posted on 2020-01-02

3536 Mitochondrial fostering: the mitochondrial genome may play a role in plant orphan gene evolution

O'Conner, S. J.; Li, L.

10.1101/2020.01.02.884874 — evolutionary biology — Posted on 2020-01-02

3537 Colon-specific immune microenvironment regulates cancer progression versus rejection

Trimaglio, G.; Tilkin-Mariame, A.-F.; Feliu, V.; Lauzeral-Vizcaino, F.; Tosolini, M.; Valle, C.; Ayyoub, M.; Neyrolles, O.; Vergnolle, N.; Rombouts, Y.; Devaud, C.

10.1101/2020.01.02.892711 — cancer biology — Posted on 2020-01-02

3538 Inactivation of LCN2/EGR1 Promotes Oligodendrocyte Progenitor Cell Differentiation and Remyelination after White Matter Injury

Li, Q.; Ru, X.; Yang, Y.; Zhao, H.; Qu, J.; Chen, W.; Pan, P.; Ruan, H.; Li, C.-J.; Feng, H.; Chen, Y.

10.1101/2020.01.02.892976 — neuroscience — Posted on 2020-01-02

3539 A Point Mutation in the RNA Recognition Motif of CSTF2 Associated with Intellectual Disability in Humans Causes Defects in 3' End Processing

Grozdanov, P. N.; Masoumzadeh, E.; Kalscheuer, V. M.; Bienvenu, T.; Billuart, P.; Latham, M. P.; Delrue, M.-A.; MacDonald, C. C.

10.1101/2020.01.02.893107 — molecular biology — Posted on 2020-01-02

3540 KDM6A mediated expression of the long noncoding RNA DINO causes TP53 tumor suppressor stabilization in Human Papillomavirus type 16 E7 expressing cells

Sharma, S.; Münger, K.

10.1101/2020.01.01.892612 — cancer biology — Posted on 2020-01-02

3541 Overcoming Genetic Drop-outs in Variants-based Lineage Tracing from Single-cell RNA Sequencing Data

Lu, T.; Park, S.; Zhu, J.; Zhan, X.; Wang, X.; Zhu, H.; Wang, T.

10.1101/2020.01.01.892562 — bioinformatics — Posted on 2020-01-02

3542 Pioglitazone rescues mitochondrial lipid remodeling and pyruvate dehydrogenase hyperactivation in hepatic insulin resistance

Shannon, C. E.; Ragavan, M.; Palavicini, J. P.; Fourcaudot, M.; Bakewell, T.; Jin, E. S.; Malloy, C. R.; Han, X.; Merritt, M. E.; Norton, L.

10.1101/2020.01.02.892992 — biochemistry — Posted on 2020-01-02

3543 Brief exposure to a diverse range of environmental stress enhances stress tolerance in the polyextremophilic Antarctic midge, Belgica antarctica

Gantz, J. D.; Philip, B. N.; Teets, N. M.; kawarasaki, Y.; Potts, L. J.; Spacht, D. E.; Benoit, J. B.; Denlinger, D. L.; Lee, R. E.

10.1101/2020.01.01.887414 — physiology — Posted on 2020-01-02

3544 Environmental shedding of toxigenic Clostridioides difficile by asymptomatic carriers: A prospective observational study

Gilboa, M.; Houri-Levi, E.; Cohen, C.; Tal, I.; rubin, c.; Feld-Simon, O.; Brom, A.; Eden- Friedman, Y.; Segal, S.; Rahav, G.; Regev-Yochay, G.

10.1101/2020.01.01.892505 — microbiology — Posted on 2020-01-02

3545 FFselect: An improved linear mixed model for genome-wide association study in populations featuring shared environments confounded by relatedness

Schultz, N. E.; Weigel, K. A.

10.1101/2020.01.01.892455 — genomics — Posted on 2020-01-02

3546 SMRT sequencing yields the chromosome-scale reference genome of tea tree, Camellia sinensis var. sinensis

Zhang, Q.-j.; Li, W.; Li, K.; Nan, H.; Shi, C.; Zhang, Y.; Dai, Z.-Y.; Lin, Y.-L.; Yang, X.-L.; Tong, Y.; Zhang, D.; Lu, C.; Wang, C.-f.; Liu, X.-x.; Jiang, W.-K.; Wang, X.-H.; Zhang, X.-C.; Liu, Z.-H.; Eichler, E.; Gao, L.-Z.

10.1101/2020.01.02.892430 — genomics — Posted on 2020-01-02

3547 Dutch population structure across space, time and GWAS design

Byrne, R. P.; van Rheenen, W.; Project MinE ALS GWAS Consortium, ; van den Berg, L. H.; Veldink, J. H.; McLaughlin, R. L.

10.1101/2020.01.01.892513 — genetics — Posted on 2020-01-02

3548 Structural colours reflect individual quality: a meta-analysis

White, T. E.

10.1101/2020.01.01.892547 — evolutionary biology — Posted on 2020-01-02

3549 Lineage Functional Types (LFTs): Characterizing functional diversity to enhance the representation of ecological behavior in Earth System Models

Griffith, D.; Osborne, C.; Edwards, E.; Bachle, S.; Beerling, D.; Bond, W.; Gallaher, T.; Helliker, B.; Lehmann, C.; Leatherman, L.; Nippert, J.; Pau, S.; Qiu, F.; Riley, W.; Smith, M.; Strömberg, C.; Taylor, L.; Ungerer, M.; Still, C.

10.1101/2020.01.01.891705 — ecology — Posted on 2020-01-02

3550 Derivation and characterization of chimera-competent eXtra-Embryonic eNdoderm 1 (XEN) cells from pig blastocysts

Telugu, B.; Park, C. H.; Jeoung, Y. H.; Uh, J.; Park, K. E.; Bridge, J.; Powells, A.; Li, J.; Pence, L.; Liu, T.; Sun, H.-X.; Gu, Y.; Shen, Y.; Wu, J.; Izpisua Belmonte, J. C.

10.1101/2020.01.02.892802 — developmental biology — Posted on 2020-01-02

3551 Elevated phosphate mediates extensive cellular toxicity: from abnormal proliferation to cell death

He, P.; Mann-Collura, O.; Fling, J.; Edara, N.; Razzaque, M. S.

10.1101/2020.01.02.892638 — cell biology — Posted on 2020-01-02

3552 Comparative study of transcriptomics-based scoring metrics for the epithelial-hybrid-mesenchymal spectrum

Chakraborty, P.; George, J. T.; Tripathi, S.; Levine, H.; Jolly, M. K.

10.1101/2020.01.02.892604 — cancer biology — Posted on 2020-01-02

3553 Multiplex generation, tracking, and functional screening of substitution mutants using a CRISPR/retron system

Lim, H.; Jun, S.; Park, M.; Lim, J.; Jeong, J.; Lee, J. H.; Bang, D.

10.1101/2020.01.02.892679 — bioengineering — Posted on 2020-01-02

3554 VIPR: Vectorial Implementation of Phase Retrieval for fast and accurate microscopic pixel-wise pupil estimation

Ferdman, B.; Nehme, E.; Weiss, L. E.; Orange, R.; Alalouf, O.; Shechtman, Y.

10.1101/2020.01.02.892661 — biophysics — Posted on 2020-01-02

3555 Disconnects in global discourses - the unintended consequences of marine mammal protection on small-scale fishers

Davis, K. J.; Alfaro-Shigueto, J.; Arlidge, W. N. S.; Burton, M.; Mangel, J. C.; Mills, M.; Milner-Gulland, E. J.; Palma Duque, J.; Romero-de-Diego, C.

10.1101/2020.01.01.892422 — ecology — Posted on 2020-01-02

3556 TLR4 signaling in neurons enhances calcium-permeable AMPAR currents and drives post-traumatic epileptogenesis

Korgaonkar, A. A.; Li, Y.; Sekhar, D.; Subramanian, D.; Guevarra, J.; Swietek, B.; Pallottie, A.; Singh, S.; Kella, K.; Elkabes, S.; Santhakumar, V.

10.1101/649780 — neuroscience — Posted on 2020-01-02

3557 Endomembrane Cation Chloride Cotransporters (CCC1s) modulate endo- and exocytosis

McKay, D. W.; Qu, Y.; McFarlane, H. E.; Situmorang, A.; Gilliham, M.; Wege, S.

10.1101/2020.01.02.893073 — plant biology — Posted on 2020-01-02

3558 Epitope-tagging of the endogenous murine BiP/GRP78/Hspa5 locus allows direct analysis of the BiP interactome and protein misfolding in vivo.

Peng, Y.; Chen, Z.; Peter, A.; Kaufman, R. J.

10.1101/2020.01.01.892539 — molecular biology — Posted on 2020-01-02

3559 The finger 2 tip loop of Activin A is required for the formation of its non-signaling complex with ACVR1 and type II Bone Morphogenetic Protein receptors

Idone, V.; Corpina, R. A.; Goebel, E. J.; Cunanan, C. J.; Dimitriou, A.; Kim, H.; Zhang, Q.; Rafique, A.; Leidich, R.; Wang, X.; McClain, J.; Jimenez, J.; Nannuru, K. C.; Rothman, N. J.; Lees-Shepard, J. B.; Thompson, T. B.; Murphy, A. J.; Economides, A. N.

10.1101/733147 — cell biology — Posted on 2020-01-02

3560 Clamping, bending, and twisting inter-domain motions in the misfold-recognising portion of UDP glucose:glycoprotein glucosyl-transferase.

Modenutti, C. P.; Blanco Capurro, J. I.; Ibba, R.; Vasiljevic, S.; Hensen, M.; Alonzi, D. S.; Chandran, A. V.; Hill, J. C.; Rushton, J.; Kumar, A.; Rubichi, S.; Lia, A.; Tax, G.; Marti, L.; Santino, A.; Marti, M.; Zitzmann, N.; Roversi, P.

10.1101/2019.12.25.888438 — biochemistry — Posted on 2020-01-02

3561 Disconnectome Associated with Progressive Ischemic Periventricular White Matter Lesions

Li, Z.; Dolui, S.; Habes, M.; Bassett, D. S.; Wolk, D.; Detre, J. A.

10.1101/2019.12.24.888081 — neuroscience — Posted on 2020-01-02

3562 sisterless A is required for the activation of Sex lethal in the germline

Goyal, R.; Baxter, E.; Van Doren, M.

10.1101/2019.12.17.880070 — developmental biology — Posted on 2020-01-02

3563 Sensorimotor peak alpha frequency is a reliable biomarker of pain sensitivity

Furman, A. J.; Prokhorenko, M.; Keaser, M. L.; Zhang, J.; Mazaheri, A.; Seminowicz, D.

10.1101/613299 — neuroscience — Posted on 2020-01-02

3564 Basal Contamination of Sequencing: Lessons from the GTEx dataset

Nieuwenhuis, T. O.; Yang, S.; Verma, R. X.; Pillalamarri, V.; Arking, D.; Rosenberg, A. Z.; McCall, M. N.; Halushka, M. K.

10.1101/602367 — genomics — Posted on 2020-01-02

3565 Endomembrane Cation Chloride Cotransporters (CCC1s) modulate endo- and exocytosis

Wege, S.; McKay, D. W.; Qu, Y.; McFarlane, H. E.; Situmorang, A.; Gilliham, M.

10.1101/2020.01.02.893073 — plant biology — Posted on 2020-01-02

3566 Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice

Chiao, Y. A.; Zhang, H.; Sweetwyne, M.; Whitson, J.; Ting, Y. S.; Basisty, N.; Pino, L.; Quarles, E.; Nguyen, N.-H.; Campbell, M.; Zhang, T.; Gaffrey, M. J.; Merrihew, G.; Wang, L.; Yue, Y.; Duan, D.; Granzier, H.; Szeto, H. H.; Qian, W.-J.; Marcinek, D.; MacCoss, M. J.; Rabinovitch, P. S.

10.1101/2020.01.02.893008 — physiology — Posted on 2020-01-02

3567 Epitope-tagging of the endogenous murine BiP/GRP78/Hspa5 locus allows direct analysis of the BiP interactome and protein misfolding in vivo.

Peng, Y.; Chen, Z.; Peter, A.; Kaufman, R. J.

10.1101/2020.01.01.892539 — molecular biology — Posted on 2020-01-02

3568 A Pairwise Distance Distribution Correction (DDC) algorithm to eliminate blinking-caused artifacts in super-resolution microscopy

Bohrer, C. H.; Yang, X.; Weng, X.; Tenner, B.; Thakur, S.; McQuillen, R.; Ross, B.; Wooten, M.; Chen, X.; Lakadamyali, M.; Zhang, J.; Roberts, E.; Xiao, J.

10.1101/768051 — biophysics — Posted on 2020-01-02

3569 Hormonal dysregulation after prolonged HPA axis activation can be explained by changes of adrenal and corticotroph masses

Karin, O.; Raz, M.; Tendler, A.; Bar, A.; Korem Kohanim, Y.; Milo, T.; Alon, U.

10.1101/2020.01.01.892596 — physiology — Posted on 2020-01-02

3570 Antibiotics-induced alterations in gut microbiol composition leads to blood-brain barrier permeability increase in rhesus monkeys

Wu, Q.; Zhang, Y.; Zhang, Y.; Lai, Q.; Xia, C.; Sun, H.; Dong, Z.; Kuang, W.; Yang, C.; Su, D.; Li, H.; Zhong, Z.

10.1101/2020.01.02.890939 — neuroscience — Posted on 2020-01-02

3571 Spatial Proximity Moderates Genotype Uncertainty in Genetic Tagging Studies

Augustine, B.; Royle, J.; Linden, D. W.; Fuller, A. K.

10.1101/2020.01.01.892463 — ecology — Posted on 2020-01-02

3572 Molecular mechanism underlying venation patterning in butterflies

Banerjee, T. D.; Monteiro, A.

10.1101/2020.01.02.892760 — developmental biology — Posted on 2020-01-02

3573 Bmf Facilitates Protein Degradation and Reduces Beclin1 Ubiquitination to Inhibit Autophagy Independent of mTOR

Delgado-Vergas, M.; Fort, S.; Tassew, D.; Tesfaigzi, Y.

10.1101/2020.01.02.892828 — cell biology — Posted on 2020-01-02

3574 CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning

Ba, Z.; Lou, J.; Dring, E. W.; Ye, A. Y.; Lin, S. G.; Jain, S.; Kieffer-Kwon, K.-R.; Casellas, R.; Alt, F. W.

10.1101/2020.01.01.891473 — immunology — Posted on 2020-01-02

3575 FGFR3 is a positive regulator of osteoblast expansion and differentiation during zebrafish skull vault development

Dambroise, E.; Ktorza, I.; Brombin, A.; Abdessalem, G.; Edouard, J.; Luka, M.; Fiedler, I.; Binder, O.; Pelle, O.; Patton, E.; Busse, B.; Menager, M.; Sohm, F.; Legeai-Mallet, L.

10.1101/2020.01.02.884155 — developmental biology — Posted on 2020-01-02

3576 AMPKα1 is essential for Glucocorticoid Receptor triggered anti-inflammatory macrophage activation

Caratti, G.; Desgeorges, T.; Juban, G.; Koenen, M.; Kozak, B.; Theret, M.; Chazaud, B.; Tuckermann, J. P.; Mounier, R.

10.1101/2020.01.02.892836 — physiology — Posted on 2020-01-02

3577 Blimp-1 is essential for Th2 cell development and allergic asthma

He, K.; Hettinga, A.; Kale, S. L.; Hu, S.; Xie, M. M.; Dent, A. L.; Ray, A.; Poholek, A. C.

10.1101/766246 — immunology — Posted on 2020-01-02

3578 New analysis pipeline for high-throughput domain-peptide affinity experiments improves SH2 interactiondata

Ronan, T.; Garnett, R.; Naegle, K. M.

10.1101/2020.01.02.892901 — systems biology — Posted on 2020-01-02

3579 Chemically Induced Chromosomal Interaction (CICI): A New Tool to Study Chromosome Dynamics and Its Biological Roles

Du, M.; Zou, F.; Yan, Y.; Bai, L.

10.1101/2020.01.01.892448 — synthetic biology — Posted on 2020-01-02

3580 Exploring Mechanisms of Glucose Uptake Regulation and Dilution Resistance in Growing Cancer Cells

Tveit, D. M.; Fjeld, G.; Drengstig, T.; Filipp, F. V.; Ruoff, P.; Thorsen, K.

10.1101/2020.01.02.892729 — cancer biology — Posted on 2020-01-02

3581 Adhesion force spectroscopy with nanostructured colloidal probes reveals nanotopography-dependent early mechanotransductive interactions at the cell membrane level

Chighizola, M.; Previdi, A.; Dini, T.; Piazzoni, C.; Lenardi, C.; Milani, P.; Schulte, C.; Podesta', A.

10.1101/2020.01.02.892919 — biophysics — Posted on 2020-01-02

3582 Improving protein alignment algorithms using amino-acid hydrophobicities - Applications of TMATCH, A new algorithm

Cavanaugh, D. P.; Chittur, K.

10.1101/2020.01.01.878769 — bioinformatics — Posted on 2020-01-02

3583 Chromosome-level assembly of the Caenorhabditis remanei genome reveals conserved patterns of nematode genome organization

Teterina, A. A.; Willis, J. H.; Phillips, P. C.

10.1101/2019.12.31.892059 — genomics — Posted on 2020-01-02

3584 WEScover: selection of whole exome sequencing vs. gene panel testing

Alvarez, W. J.; Lee, I.-H.; Hernandez-Ferrer, C.; Mandl, K.; Kong, S. W.

10.1101/367607 — bioinformatics — Posted on 2020-01-02

3585 Interference of pH buffer with Pb2+-peripheral domain interactions: obstacle or opportunity?

Katti, S.; Igumenova, T. I.

10.1101/2019.12.31.892232 — biochemistry — Posted on 2020-01-02

3586 Multilevel integrative transcriptome analyses in humans and humanized mice define in vivo human lncRNA metabolic regulators

Ruan, X.; Li, P.; Ma, Y.; Jiang, C.-f.; Chen, Y.; Shi, Y.; Gupta, N.; Seifuddin, F.; Pirooznia, M.; Suemizu, H.; Ohnishi, Y.; Yoneda, N.; Nishiwaki, M.; Cao, H.

10.1101/2020.01.01.884023 — physiology — Posted on 2020-01-02

3587 Multiple Dimerizing Motifs Modulate the Dimerizations of the Syndecan Transmembrane Domains

Chen, J.; Wang, F.; He, C.; Luo, S.-Z.

10.1101/2019.12.31.891929 — molecular biology — Posted on 2020-01-02

3588 Viscous medium-based crystal support in sample holder for fixed-target serial femtosecond crystallography

Lee, K.; Lee, D.; Baek, S.; Park, J.; Lee, S. J.; Park, S.; Chung, W. K.; Lee, J.-L.; Cho, H.-S.; Cho, Y.; Nam, K. H.

10.1101/2019.12.31.892265 — biophysics — Posted on 2020-01-02

3589 Human Tau Isoform Aggregation and Selective Detection of Misfolded Tau from Post-Mortem Alzheimer's Disease Brains

Wu, L.; Wang, Z.; Lad, S.; Dougharty, D.; Madhavan, S.; Marcus, M.; Henderson, F.; Ray, W. K.; Tan, C.; Siedlak, S.; Li, J.; Helm, R. F.; Zhu, X.; Bloom, G. S.; Zou, W.; Xu, B.

10.1101/2019.12.31.876946 — pathology — Posted on 2020-01-02

3590 Dorsal anterior cingulate cortex neurons only partially integrate determinants of value

Azab, H.; Hayden, B.

10.1101/2020.01.01.892380 — neuroscience — Posted on 2020-01-02

3591 Single cell atlas of trisomy 21 cerebral cortex

Zhang, J.; wang, S.; Xu, Z.; Ding, X.; Li, C.; Zhang, Y.; Chen, Y.; Zhong, J.; Liang, L.; Chai, C.; Wang, X.; Xiang, R.; Zhu, J.; Lin, X.; Ding, P.; Zhang, Q.; Wang, M.; Feng, Q.; Zhang, Z.; Guo, G.; Xue, S.; Jin, L.; He, Z.; Yan, L.; Xiao, B.; Zhang, C.; Xu, Y.; Li, W.; Zhang, Y.; Wu, W.; Jiang, S.; Xia, J.; Gao, Y.; Wang, L.; Dong, S.; Liu, S.; Zhu, S.; Chen, F.; Chen, D.; Xu, X.

10.1101/2020.01.01.892398 — neuroscience — Posted on 2020-01-02

3592 Linking the association between circRNAs and Alzheimer's disease progression by multi-tissue circular RNA characterization

Lo, I.; Hill, J.; Vilhjalmsson, B. J.; Kjems, J.

10.1101/2019.12.31.892026 — genomics — Posted on 2020-01-02

3593 Simultaneous classification of neuroactive compounds in zebrafish

Myers-Turnbull, D.; Taylor, J. C.; Helsell, C.; Tummino, T. A.; Mccarroll, M. N.; Alexander, R.; Ki, C. S.; Gendelev, L.; Kokel, D.

10.1101/2020.01.01.891432 — systems biology — Posted on 2020-01-02

3594 Value and choice as separable, stable representations in orbitofrontal cortex

Kimmel, D. L.; Elsayed, G. F.; Cunningham, J. P.; Newsome, W. T.

10.1101/2019.12.31.892109 — neuroscience — Posted on 2020-01-02

3595 Face recognition depends on specialized mechanisms tuned to view-invariant facial features: Insights from deep neural networks optimized for face or object recognition

Abudarham, N.; Yovel, G.

10.1101/2020.01.01.890277 — neuroscience — Posted on 2020-01-02

3596 Brucella suppress innate immunity by down-regulating STING expression in macrophages

Khan, M.; Harms, J. S.; Liu, Y.; Eickhoff, J.; Tan, J. W.; Hu, T.; Cai, F.; Guimaraes, E.; Oliveira, S. C.; Dahl, R.; Gutman, D.; Barber, G. N.; Splitter, G. A.; Smith, J. A.

10.1101/2019.12.31.891051 — microbiology — Posted on 2020-01-02

Chapman, A. R.; Lee, D. F.; Cai, W.; Ma, W.; Li, X.; Sun, W.; Xie, X. S.

10.1101/2019.12.31.892190 — genomics — Posted on 2020-01-02

3598 Recurrent pre-leukemic deletions in myeloid malignancies are the result of DNA double-strand breaks followed by microhomology-mediated end joining

Feldman, T.; Bercovich, A.; Moskovitz, Y.; Chapal-Ilani, N.; Mitchell, A.; Medeiros, J. J.; Kaushansky, N.; Biezuner, T.; Minden, M. D.; Gupta, V.; Tanay, A.; Shlush, L. I.

10.1101/2020.01.01.888610 — genomics — Posted on 2020-01-02

3599 BET bromodomain inhibitor HMBA synergizes with MEK inhibition in treatment of malignant glioma

Funck-Brentano, E.; Vizlin Hodzic, D.; Nilsson, J. A.; Nilsson, L. M.

10.1101/2020.01.01.891739 — cancer biology — Posted on 2020-01-02

3600 GeneMark-EP and -EP+: automatic eukaryotic gene prediction supported by spliced aligned proteins

Bruna, T.; Lomsadze, A.; Borodovsky, M.

10.1101/2019.12.31.891218 — bioinformatics — Posted on 2020-01-02

3601 An antigenic diversification threshold for falciparum malaria and its control at high endemicity

He, Q.; Pascual, M.

10.1101/2020.01.01.892406 — evolutionary biology — Posted on 2020-01-02

3602 A Waddington Epigenetic Landscape for the C. elegans embryo

Elewa, A.

10.1101/2020.01.01.892414 — developmental biology — Posted on 2020-01-02

3603 Granular Transcriptomic Signatures Derived from Independent Component Analysis of Bulk Nervous Tissue for Studying Labile Brain Physiologies

Rusan, Z. M.; Cary, M. P.; Bainton, R. J.

10.1101/2020.01.01.892281 — bioinformatics — Posted on 2020-01-02

3604 Chaperonin Abundance Boosts Bacterial Fitness

Kumar, S. C. M.; Chugh, K.; Dutta, A.; Mahamkali, V.; Bose, T.; Mande, S. S.; mande, s.; Lund, P. A.

10.1101/2019.12.31.891820 — biochemistry — Posted on 2020-01-02

3605 A single-cell transcriptional roadmap of the mouse and human lymph node lymphatic vasculature

Xiang, M.; Grosso, R. A.; Takeda, A.; Pan, J.; Bekkhus, T.; Brulois, K.; Dermadi, D.; Nordling, S.; Vanlandewijck, M.; Jalkanen, S.; Ulvmar, M. H.; Butcher, E. C.

10.1101/2019.12.31.892166 — systems biology — Posted on 2020-01-02

3606 Teratogenic Drug Topiramate Upregulates TGFβ1 and SOX9 Expression in Primary Palatal Mesenchyme Cells

Rafi, S. K.; Goering, J. P.; Olm-Shipman, A. J.; Hipp, L. A.; Ernst, N. J.; Wilson, N. R.; Hall, E. G.; Gunewardena, S.; Saadi, I.

10.1101/2019.12.31.892042 — pharmacology and toxicology — Posted on 2020-01-02

3607 The rebound response plays a role in the motion mechanisms and perception

Cohen-Duwek, H.; Spitzer, H.

10.1101/2019.12.31.891580 — neuroscience — Posted on 2020-01-02

3608 Weekend light shifts evoke persistent Drosophila circadian neural network desynchrony

Nave, C.; Roberts, L.; Hwu, P.; Estrella, J. D.; Vo, T. C.; Nguyen, T. H.; Pervolarakis, N.; Shaw, P. J.; Leise, T. L.; Holmes, T. C.

10.1101/2019.12.31.891507 — neuroscience — Posted on 2020-01-02

3609 Acute Stress Desensitizes Hypothalamic CRH Neurons to Norepinephrine and Physiological Stress

Jiang, Z.; Chen, C.; Weiss, G. L.; Fu, X.; Fisher, M. O.; Begley, J. C.; Stevens, C. R.; Harrison, L. M.; Tasker, J. G.

10.1101/2019.12.31.891408 — neuroscience — Posted on 2020-01-02

3610 Material category determined by specular reflection structure mediates the processing of image features for perceived gloss

Schmid, A. C.; Barla, P.; Doerschner, K.

10.1101/2019.12.31.892083 — neuroscience — Posted on 2020-01-02

3611 Molecular Diversity Among Adult Hippocampal and Entorhinal Cells

Franjic, D.; Choi, J.; Skarica, M.; Xu, C.; Li, Q.; Ma, S.; Tebbenkamp, A. T. N.; Santpere, G.; Arellano, J. I.; Gudelj, I.; Jankovic-Rapan, L.; Sousa, A. M. M.; Rakic, P.; Sestan, N.

10.1101/2019.12.31.889139 — neuroscience — Posted on 2020-01-02

3612 Associative Learning and Motivation Differentially Requires Neuroligin-1 at Excitatory Synapses

Luo, J.; Tan, J. M.; Nithianantharajah, J.

10.1101/2020.01.01.890798 — neuroscience — Posted on 2020-01-02

3613 Identification of human CD4+ T cell populations with distinct antitumor activity

Nelson, M. H.; Knochelmann, H. M.; Bailey, S. R.; Huff, L. W.; Bowers, J. S.; Majchrzak, K.; Wyatt, M. M.; Rubinstein, M. P.; Mehrotra, S.; Nishimura, M. I.; Armeson, K.; Giresi, P. G.; Zilliox, M. J.; Broxmeyer, H. E.; Paulos, C. M.

10.1101/2019.12.31.891317 — immunology — Posted on 2020-01-02

3614 Zooplankters in an oligotrophic ocean: contrasts in the niches of the foraminifers Globigerinoides ruber and Trilobatus sacculifer in the tropical South Pacific

Scott, G. H.

10.1101/2019.12.31.892208 — ecology — Posted on 2020-01-02

3615 Rapid quantitative assessment of fish larvae community composition using metabarcoding

Ratcliffe, F. C.; Uren Webster, T. M.; Rodriguez Barreto, D.; O'Rorke, R.; Garcia de Leaniz, C.; Consuegra, S.

10.1101/2020.01.01.884544 — ecology — Posted on 2020-01-02

3616 Consensus Features Nested Cross-Validation

Parvandeh, S.; Yeh, H.-W.; Paulus, M. P.; McKinney, B.

10.1101/2019.12.31.891895 — bioinformatics — Posted on 2020-01-02

3617 The predictive power of the microbiome exceeds that of genome-wide association studies in the discrimination of complex human disease

Tierney, B. T.; He, Y.; Church, G. M.; Segal, E. J.; Kostic, A. D.; Patel, C. J.

10.1101/2019.12.31.891978 — bioinformatics — Posted on 2020-01-02

3618 Missing the forest because of the trees: Slower alternations during binocular rivalry are associated with lower levels of visual detail

Ho, N. S. P.; Baker, D. H.; Karapanagiotidis, T.; Seli, P.; Wang, H.-t.; Leech, R.; Bernhardt, B.; Margulies, D.; Jefferies, E.; Smallwood, J.

10.1101/2019.12.31.891853 — neuroscience — Posted on 2020-01-02

3619 Refinement and reactivation of a taste-responsive hippocampal network

Herzog, L. E.; Katz, D. B.; Jadhav, S. P.

10.1101/744714 — neuroscience — Posted on 2020-01-02

3620 Reliable readout of mixture components from small populations of piriform cortical neurons

Penker, S.; Licht, T.; Rokni, D.

10.1101/2019.12.26.888693 — neuroscience — Posted on 2020-01-02

3621 In V4, pair-wise synchony and correlations depend on the structure of the population code

Koren, V.; Andrei, A. R.; Hu, M.; Dragoi, V.; Obermayer, K.

10.1101/645135 — neuroscience — Posted on 2020-01-02

3622 First near complete haplotype phased genome assembly of River buffalo (Bubalus bubalis)

Sudhakar, A.; Kothandaraman, H.; Nayee, N.; Saha, S.; Baghel, D. S.; Kishore, G.; Peddamma, S.; Singh, R. B.; Schatz, M.

10.1101/618785 — genomics — Posted on 2020-01-02

3623 Ultra-fast electroporation of giant unilamellar vesicles -- Experimental validation of a molecular model

Sözer, E. B.; Haldar, S.; Blank, P. S.; Castellani, F.; Vernier, P. T.; Zimmerberg, J.

10.1101/2020.01.01.890137 — biophysics — Posted on 2020-01-02

3624 Sex differences in central inflammatory pain sensitization are associated with differential expression of glycine receptors and GLP-1 at the spinal cord

Mariqueo, T. A.; Amestica, G.; Pino, J.; Barra, R.; Stehberg, J.; Gonzalez, W.; Castillo, K.

10.1101/2019.12.31.892133 — physiology — Posted on 2020-01-02

3625 Massively parallel, time-resolved single-cell RNA sequencing with scNT-Seq

Qiu, Q.; Hu, P.; Govek, K. W.; Camara, P. G.; Wu, H.

10.1101/2019.12.19.882050 — genomics — Posted on 2020-01-02

3626 Cdc48 Co-Factor Shp1 Regulates Signal-Induced SCFMet30 Disassembly

Lauinger, L.; Flick, K.; Yen, J. L.; Mathur, R.; Kaiser, P.

10.1101/2019.12.13.876029 — biochemistry — Posted on 2020-01-02

3627 On the expression of co-operative feeding behaviour in 3rd instar Drosophila melanogaster larvae

Khodaei, L.; Newman, T.; Lum, S.; Ngo, H.; Maoloni, M.; Long, T. A. F.

10.1101/678631 — evolutionary biology — Posted on 2020-01-02

3628 Histone modification dynamics as revealed by a multicolor immunofluorescence-based single-cell analysis

Hayashi-Takanaka, Y.; Kina, Y.; Nakamura, F.; Becking, L. E.; Nakao, Y.; Nagase, T.; Nozaki, N.; Kimura, H.

10.1101/2020.01.01.892299 — cell biology — Posted on 2020-01-01

3629 Euplotid: A quantized geometric model of the eukaryotic cell

Borges-Rivera, D.

10.1101/170159 — biophysics — Posted on 2020-01-02

3630 Molecular height measurement by cell surface optical profilometry (CSOP)

Son, S.; Takatori, S.; Belardi, B.; Podolski, M.; Bakalar, M. H.; Fletcher, D. A.

10.1101/2019.12.31.892075 — biophysics — Posted on 2020-01-01

3631 Developmental regulation of oocyte lipid uptake via 'patent' tricellular junctions in Drosophila epithelium

Row, S.; Deng, W.-M.

10.1101/2019.12.31.891838 — developmental biology — Posted on 2020-01-01

3632 ATR expands embryonic stem cell fate potential in response to replication stress

Atashpaz, S.; Samadi Shams, S.; Gonzalez, J. M.; Sebestyen, E.; Arghavanifard, N.; Gnocchi, A.; Albers, E.; Minardi, S.; Faga, G.; Soffientini, P.; Allievi, E.; Cancila, V.; Bachi, A.; Fernandez-Capetillo, O.; Tripodo, C.; Ferrari, F.; Lopez-Contreras, A. J.; Costanzo, V.

10.1101/2020.01.01.888354 — cell biology — Posted on 2020-01-01

3633 Dual roles of the Sterol Recognition Region in Hedgehog protein modification

Purohit, R.; Peng, D. S.; Vielmas, E.; Ondrus, A. E.

10.1101/2019.12.31.892067 — biochemistry — Posted on 2020-01-01

3634 ROTAVIRUS INDUCES INTERCELLULAR CALCIUM WAVES THROUGH ADP SIGNALING

Chang-Graham, A. C.; Perry, J. L.; Engevik, M. A.; Danhof, H. A.; Scribano, F.; Engevik, K. A.; Nelson, J.; Kellen, J. S.; Strtak, A. C.; Palla, N. S.; Kunapuli, S. P.; Estes, M. K.; Versalovic, J.; Britton, R. A.; Hyser, J. M.

10.1101/2019.12.31.892018 — microbiology — Posted on 2020-01-01

3635 Single-cell RNA-seq reveals endoimmune cells in zebrafish

Shi, Y.; Qian, P.; Sheng, J.; Zhang, X.; Wang, X.; Zhao, J.; Wei, G.; Liu, X.; Xie, G.; Liu, D.

10.1101/2019.12.31.892240 — cell biology — Posted on 2020-01-01

3636 ACSL3 is a novel GABARAPL2 interactor that links ufmylation and lipid droplet biogenesis

Eck, F.; Kaulich, M.; Behrends, C.

10.1101/2020.01.01.892521 — cell biology — Posted on 2020-01-01

3637 Frequency switching between oscillatory homeostats and the regulation of p53

Ruoff, P.; Nishiyama, N.

10.1101/2019.12.31.891622 — systems biology — Posted on 2020-01-01

3638 Hyaluronic Acid on the Urokinase Sustained Release with a Hydrogel System Composed of Poloxamer 407: Enhanced Stability of Intracellular Interaction by Adding HA.

Hsieh, H. Y.; Lin, W. Y.; Lee, A. L.; Li, Y. C.; Chen, Y. J.; Chen, K. C.; Young, T.-H.

10.1101/2019.12.31.891614 — pharmacology and toxicology — Posted on 2020-01-01

3639 Differences in Characteristics of Medicare Patients Treated by Ophthalmologists and Optometrists

Miller, D.; Stewart, M. W.; Gagne, J. J.; Wagner, A. L.; Lee, A. Y.

10.1101/2019.12.31.891606 — bioinformatics — Posted on 2020-01-01

3640 Heritability in friendship networks

Neugart, M.; Yildirim, S.

10.1101/2019.12.31.891598 — genetics — Posted on 2020-01-01

3641 Examining go-or-grow using fluorescent cell-cycle indicators and cell cycle-inhibiting drugs

Vittadello, S. T.; McCue, S. W.; Gunasingh, G.; Haass, N. K.; Simpson, M. J.

10.1101/797142 — biophysics — Posted on 2020-01-01

3642 Deep evolutionary analysis reveals the design principles of fold A glycosyltransferases

Taujale, R.; Venkat, A.; Huang, L.-C.; Yeung, W.; Rasheed, K.; Edison, A. S.; Moremen, K. W.; Kannan, N.

10.1101/2019.12.31.891697 — bioinformatics — Posted on 2020-01-01

3643 RNA Sequencing by Direct Tagmentation of RNA/DNA Hybrids

Di, L.; Fu, Y.; Sun, Y.; Li, J.; Liu, L.; Yao, J.; Wang, G.; Wu, Y.; Lao, K.; Lee, R. W.; Zheng, G.; Xu, J.; Oh, J.; Wang, D.; Xie, X. S.; Huang, Y.; Wang, J.