bioRxiv directory

Roth, T. L.; Yu, R.; Shifrut, E.; Hiatt, J.; Li, H.; Schumann, K.; Tobin, V.; Ferris, A. M.; Chen, J.; Schickel, J.-N.; Pellerin, L.; Carmody, D.; Alkorta-Aranburu, G.; Del Gaudio, D.; Cho, M.; Matsumoto, H.; Morell, M.; Mao, Y.; Nguyen, D.; Quadros, R.; Gurumurthy, C.; Smith, B.; Haugwitz, M.; Hughes, S. H.; Weissman, J.; May, A. P.; Kupfer, G.; Greeley, S.; Bacchetta, R.; Meffre, E.; Roncarolo, M. G.; Romberg, N.; Herold, K. C.; Leonetti, M. D.; Marson, A.

10.1101/183418 — genetics — Posted on 2017-08-31

3 Conserving amphibians in the face of land development: integrating field experiments as a planning tool

Felson, A. J.

10.1101/183343 — ecology — Posted on 2017-08-31

4 A minimal model of protein allocation during phototrophic growth

Faizi, M.; Zavrel, T.; Loureiro, C.; Cerveny, J.; Steuer, R.

10.1101/183236 — systems biology — Posted on 2017-08-31

5 Fitting mathematical models of biochemical pathways to steady state perturbation response data without simulating perturbation experiments

Santra, T.

10.1101/183194 — systems biology — Posted on 2017-08-31

6 HPeV-3 predominated among Parechovirus A positive infants in the summer of 2013-2014 in Queensland, Australia.

McNeale, D.; Wang, C. Y. T.; Arden, K. E.; Mackay, I. M.

10.1101/182436 — microbiology — Posted on 2017-08-31

7 Validation of RT-qPCR approaches to monitor Pseudomonas syringae gene expression during infection and exposure to pattern-triggered immunity

Smith, A.; Lovelace, A.; Kvitko, B.

10.1101/183269 — microbiology — Posted on 2017-08-31

8 Functional traits and community composition: multilevel models outperform community-weighted means

Miller, J. E. D.; Ives, A.; Damschen, E.

10.1101/183442 — ecology — Posted on 2017-08-31

9 Applying the auxin-inducible degradation (AID) system for rapid protein depletion in mammalian cells

Lambrus, B. G.; Moyer, T. C.; Holland, A.

10.1101/182840 — cell biology — Posted on 2017-08-31

10 CancerDiscover: A configurable pipeline for cancer prediction and biomarker identification using machine learning framework

Mohammed, A.; Biegert, G.; Adamec, J.; Helikar, T.

10.1101/182998 — bioinformatics — Posted on 2017-08-31

11 Recovering genomic clusters of secondary metabolites from lakes: a Metagenomics 2.0 approach

Cuadrat, R.; Ionescu, D.; Davila, A. M. R.; Grossart, H.-P.

10.1101/183061 — bioinformatics — Posted on 2017-08-31

12 Semi-Parametric Covariate-Modulated Local False Discovery Rate For Genome-Wide Association Studies

Zablocki, R.; Levine, R.; Schork, A.; Xu, S.; Wang, Y.; Fan, C.; Thompson, W.

10.1101/183384 — bioinformatics — Posted on 2017-08-31

13 Deeper sequencing at unexpected CRISPR/Cas9 off-target sites in vivo : A response to Editas, Intellia, Beacon, ToolGen and others

Schaefer, K. A.; Wu, W.-H.; Darbro, B. W.; Colgan, D. F.; Tsang, S. H.; Bassuk, A. G.; Mahajan, V. B.

10.1101/154450 — bioengineering — Posted on 2017-08-31

14 Rosetta Antibody Design (RAbD): A General Framework for Computational Antibody Design

Adolf-Bryfogle, J.; Kalyuzhniy, O.; Kubitz, M.; Weitzner, B. D.; Hu, X.; Adachi, Y.; Schief, W. R.; Dunbrack, R. L.

10.1101/183350 — bioengineering — Posted on 2017-08-31

15 Transcriptomes of major renal collecting-duct cell types in mouse identified by single-cell RNA-Seq

Chen, L.; Lee, J. W.; Chou, C.-L.; Nair, A.; Battistone, M. A.; Paunescu, T.; Mekulova, M.; Breton, S.; Verlander, J. W.; Wall, S.; Brown, D.; Burg, M. B.; Knepper, M. A.

10.1101/183376 — physiology — Posted on 2017-08-31

16 Detection and accurate False Discovery Rate control of differentially methylated regions from Whole Genome Bisulfite Sequencing

Korthauer, K.; Chakraborty, S.; Benjamini, Y.; Irizarry, R. A.

10.1101/183210 — genomics — Posted on 2017-08-31

17 HPeV-3 predominated among Parechovirus A positive infants in the summer of 2013-2014 in Queensland, Australia.

McNeale, D.; Wang, C. Y. T.; Arden, K. E.; Mackay, I. M.

10.1101/182436 — microbiology — Posted on 2017-08-31

18 Network Architecture and Mutational Sensitivity of the C. elegans Metabolome

Johnson, L. M.; Chandler, L. M.; Davies, S. K.; Baer, C. F.

10.1101/181511 — systems biology — Posted on 2017-08-31

19 Case report: intermittent fasting and probiotic yogurt consumption are associated with reduction of serum alpha-N-acetylgalactosaminidase and increased urinary excretion of lipophilic toxicants

Blythe, J.; Pacini, S.

10.1101/177774 — pharmacology and toxicology — Posted on 2017-08-31

20 Structural and functional diversity of a dense sample of retinal ganglion cells

Bae, J. A.; Mu, S.; Kim, J. S.; Turner, N. L.; Tartavull, I.; Kemnitz, N.; Jordan, C. S.; Norton, A. D.; Silversmith, W. M.; Prentki, R.; Sorek, M.; David, C.; Jones, D. L.; Bland, D.; Sterling, A. L. R.; Park, J.; Briggman, K. L.; Seung, H. S.; the EyeWirers,

10.1101/182758 — neuroscience — Posted on 2017-08-31

21 RNA-dependent intergenerational inheritance of enhanced synaptic plasticity after environmental enrichment

Benito, E.; Kerimoglu, C.; Ramachandran, B.; Zhou, Q.; Pena, T.; Capece, V.; Jain, G.; Burkhardt, S.; Stilling, R.; Edbauer, D.; Dean, C.; Fischer, A.

10.1101/178814 — neuroscience — Posted on 2017-08-31

22 Functional Diversification of Tripeptidyl Peptidase and Endopeptidase Sedolisins in Fungi

Orts, F.; ten Have, A.

10.1101/167379 — bioinformatics — Posted on 2017-08-31

23 Adeno-associated virus mediated gene delivery: Implications for scalable in vitro and in vivo cardiac optogenetic models

Ambrosi, C. M.; Sadananda, G.; Klimas, A.; Entcheva, E.

10.1101/183319 — bioengineering — Posted on 2017-08-31

24 Dopaminergic Modulation Of Hemodynamic Signal Variability And The Functional Connectome During Cognitive Performance

Alavash, M.; Lim, S.-J.; Thiel, C.; Sehm, B.; Deserno, L.; Obleser, J.

10.1101/130021 — neuroscience — Posted on 2017-08-31

25 Single-cell RNA-seq of dopaminergic neurons informs candidate gene selection for sporadic Parkinson’s disease

Hook, P.; McClymont, S. A.; Cannon, G. H.; Law, W. D.; Morton, A. J.; Goff, L. A.; McCallion, A. S.

10.1101/148049 — genetics — Posted on 2017-08-31

26 Resurrecting ancestral genes in bacteria to interpret ancient biosignatures

Kacar, B.; Guy, L.; Smith, E.; Baross, J. A.

10.1101/164038 — evolutionary biology — Posted on 2017-08-31

27 The actin cytoskeleton governs apical mitosis and daughter cell dispersion in intestinal epithelia

McKinley, K. L.; Stuurman, N.; Klein, O. D.; Vale, R. D.

10.1101/183301 — cell biology — Posted on 2017-08-31

28 Discovery of Resistance Pathways to Fibroblast Growth Factor Receptor inhibition in Bladder Cancer

Pal, S. K.; He, M.; Jones, J.

10.1101/183293 — cancer biology — Posted on 2017-08-31

29 Hemodynamic forces tune the arrest, adhesion and extravasation of circulating tumor cells

Follain, G.; Osmani, N.; Azevedo, S.; Allio, G.; Mercier, L.; Karreman, M.; Solecki, G.; Fekonja, N.; Hille, C.; Chabannes, V.; Dolle, G.; Metivet, T.; Prudhomme, C.; Ruthensteiner, B.; Kemmling, A.; Siemonsen, S.; Schneider, T.; Fiehler, J.; Glatzel, M.; Winkler, F.; Schwab, Y.; Pantel, K.; Harlepp, S.; Goetz, J. G.

10.1101/183046 — cancer biology — Posted on 2017-08-31

30 lme4qtl: linear mixed models with flexible covariance structure for genetic studies of related individuals

Ziyatdinov, A.; Vazquez-Santiago, M.; Brunel, H.; Martinez-Perez, A.; Aschard, H.; Soria, J. M.

10.1101/139816 — bioinformatics — Posted on 2017-08-31

31 Systematic integration of biomedical knowledge prioritizes drugs for repurposing

Himmelstein, D. S.; Lizee, A.; Hessler, C.; Brueggeman, L.; Chen, S. L.; Hadley, D.; Green, A.; Khankhanian, P.; Baranzini, S. E.

10.1101/087619 — bioinformatics — Posted on 2017-08-31

32 Cryo-EM shows how dynactin recruits two dyneins for faster movement

Urnavicius, L.; Lau, C. K.; Elshenawy, M. M.; Morales-Rios, E.; Motz, C.; Yildiz, A.; Carter, A. P.

10.1101/183160 — molecular biology — Posted on 2017-08-31

33 Cord blood buffy coat DNA methylation is comparable to whole cord blood methylation

Dou, J.; Schmidt, R. J.; Benke, K. S.; Newschaffer, C.; Hertz-Picciotto, I.; Croen, L. A.; Iosif, A.-M.; LaSalle, J.; Fallin, M. D.; Bakulski, K.

10.1101/181057 — epidemiology — Posted on 2017-08-31

34 Timescales of influenza A/H3N2 antibody dynamics

Kucharski, A.; Cummings, D.; Riley, S.

10.1101/183111 — epidemiology — Posted on 2017-08-31

35 High throughput expression profiling and in situ screening of circular RNAs in tissues

Zaghlool, A.; Ameur, A.; Wu, C.; Westholm, J.; Niazi, A.; Manivannan, M.; Bramlett, K.; Nilsson, M.; Feuk, L.

10.1101/183020 — genomics — Posted on 2017-08-31

36 Patterns of sedentary and active time accumulation are associated with mortality in US adults: The NHANES study

Di, J.; Leroux, A.; Urbanek, J.; Varadhan, R.; Spira, A.; Schrack, J.; Zipunnikov, V.

10.1101/182337 — epidemiology — Posted on 2017-08-31

37 Neck muscle spindle noise biases reaches in a multi-sensory integration task

Abedi Khoozani, P.; Blohm, G.

10.1101/182907 — neuroscience — Posted on 2017-08-31

38 Alterations in neurovascular coupling following acute traumatic brain injury

Jang, H.; Huang, S.; Hammer, D. X.; Wang, L.; Ye, M.; Welle, C. G.; Fisher, J. A. N.

10.1101/183129 — neuroscience — Posted on 2017-08-31

39 Gene expression drives the evolution of dominance

Huber, C. D.; Durvasula, A.; Hancock, A. M.; Lohmueller, K. E.

10.1101/182865 — genomics — Posted on 2017-08-31

40 Comparison of single genome and allele frequency data reveals discordant demographic histories

Beichman, A.; Phung, T.; Lohmueller, K. E.

10.1101/182899 — evolutionary biology — Posted on 2017-08-31

41 Water relations of Calycanthus flowers: hydraulic conductance, capacitance, and embolism resistance

Roddy, A. B.; Simonin, K. A.; McCulloh, K. A.; Brodersen, C. R.; Dawson, T. E.

10.1101/182915 — ecology — Posted on 2017-08-31

42 Lessons Learned: Recommendations for Establishing Critical Periodic Scientific Benchmarking

Capella-Gutierrez, S.; de la Iglesia, D.; Haas, J.; Lourenco, A.; Fernandez Gonzalez, J. M.; Repchevsky, D.; Dessimoz, C.; Schwede, T.; Notredame, C.; Gelpi, J. L.; Valencia, A.

10.1101/181677 — bioinformatics — Posted on 2017-08-31

43 Unsupervised learning of DNA sequence features using a convolutional restricted Boltzmann machine

Kopp, W.; Schulte-Sasse, R.

10.1101/183095 — bioinformatics — Posted on 2017-08-31

44 SpliceVec: distributed feature representations for splice junction prediction

Dutta, A.; Dubey, T.; Singh, K. K.; Anand, A.

10.1101/183087 — bioinformatics — Posted on 2017-08-31

45 The statistical nature of geometric reasoning

Hart, Y.; Dillon, M. R.; Marantan, A.; Cardenas, A. L.; Spelke, E.; Mahadevan, L.

10.1101/183152 — animal behavior and cognition — Posted on 2017-08-31

46 Cellomics approach for high-throughput functional annotation of Caenorhabditis elegans neural network

Aoki, W.; Matsukura, H.; Yamauchi, Y.; Yokoyama, H.; Hasegawa, K.; Shinya, R.; Ueda, M.

10.1101/182923 — neuroscience — Posted on 2017-08-31

47 Automated cell cycle and cell size measurements for single-cell gene expression studies

Guillemin, A.; Richard, A.; Gonin-Giraud, S.; Gandrillon, O.

10.1101/182766 — cell biology — Posted on 2017-08-31

48 How asbestos drives the tissue towards tumors: YAP activation, macrophage and mesothelial precursor recruitment, RNA editing and somatic mutations

Rehrauer, H.; Wu, L.; Blum, W.; Pecze, L.; Henzi, T.; Serre-Beinier, V.; Aquino, C.; Vrugt, B.; de Perrot, M.; Schwaller, B.; Felley-Bosco, E.

10.1101/182980 — cancer biology — Posted on 2017-08-31

49 Structure-kinetic-thermodynamic relationships for peptide secondary structure formation identified from transition network properties

Rudzinski, J. F.; Bereau, T.

10.1101/183053 — biophysics — Posted on 2017-08-31

50 Functional characterization and discovery of modulators of SbMATE, the agronomically important aluminium tolerance transporter from Sorghum bicolor

Doshi, R.; McGrath, A. P.; Pineros, M. A.; Szewczyk, P.; Garza, D. M.; Kochian, L. V.; Chang, G.

10.1101/182964 — plant biology — Posted on 2017-08-31

51 Streptolysin-induced endoplasmic reticulum stress promotes group A streptococcal in vivo biofilm formation and necrotizing fasciitis

Vajjala, A.; Biswas, D.; Chong, K.; Tay, W. H.; Hanski, E.; Kline, K.

10.1101/183012 — microbiology — Posted on 2017-08-31

52 Local and global chromatin interactions are altered by large genomic deletions associated with human brain development

Zhang, Y.; Zhang, X.; Zhu, X.; Purmann, C.; Haney, M.; Ward, T.; Yao, J.; Weissman, S.; Urban, A.

10.1101/182451 — genetics — Posted on 2017-08-31

53 Single-cell analysis of early antiviral gene expression reveals a determinant of stochastic IFNB1 expression

Doganay, S.; Lee, M. Y.; Baum, A.; Peh, J.; Hwang, S.-Y.; Yoo, J.-Y.; Hergenrother, P. J.; Garcia-Sastre, A.; Myong, S.; Ha, T.

10.1101/182972 — biophysics — Posted on 2017-08-31

54 Hsf1 and Hsp70 constitute a two-component feedback loop that regulates the yeast heat shock response

Krakowiak, J.; Zheng, X.; Patel, N.; Anandhakumar, J.; Valerius, K.; Gross, D. S.; Khalil, A. S.; Pincus, D.

10.1101/183137 — biochemistry — Posted on 2017-08-31

55 Decline of auditory-motor speech processing in older adults with hearing loss

Panouilleres, M.; Mottonen, R.

10.1101/169235 — neuroscience — Posted on 2017-08-31

56 Reactive Oxygen Species Regulate Activity-Dependent Neuronal Structural Plasticity in Drosophila

Oswald, M. C. W.; Brooks, P. S.; Zwart, M. F.; Mukherjee, A.; West, R. J. H.; Morarach, K.; Sweeney, S. T.; Landgraf, M.

10.1101/081968 — neuroscience — Posted on 2017-08-31

57 DNA methylation profiling of breast cancer cell lines along the epithelial mesenchymal spectrum - implications for the choice of circulating tumour DNA methylation markers

Viet-Phuong Le, A.; Szaumkessel, M.; Tan, T. Z.; Thiery, J.-P.; Thompson, E. W.; Dobrovic, A.

10.1101/182600 — cancer biology — Posted on 2017-08-31

58 R2DGC: Threshold-free peak alignment and identification for 2D gas chromatography mass spectrometry in R

Ramaker, R. C.; Gordon, E.; Cooper, S. J.

10.1101/179168 — bioinformatics — Posted on 2017-08-31

59 Tagmentation-Based Mapping (TagMap) of Mobile DNA Genomic Insertion Sites

Stern, D. L.

10.1101/037762 — molecular biology — Posted on 2017-08-31

60 Identification of a novel interspecific hybrid yeast from a metagenomic spontaneously inoculated beer sample using Hi-C

Smukowski Heil, C.; Burton, J. N.; Liachko, I.; Friedrich, A.; Hanson, N. A.; Morris, C. L.; Schacherer, J.; Shendure, J.; Thomas, J. H.; Dunham, M. J.

10.1101/150722 — genomics — Posted on 2017-08-31

61 Language evolution to revolution: from a slowly developing finite communication system with many words to infinite modern language

Vyshedskiy, A.

10.1101/166520 — evolutionary biology — Posted on 2017-08-31

62 Habits without Values

Miller, K.; Shenhav, A.; Ludvig, E.

10.1101/067603 — animal behavior and cognition — Posted on 2017-08-31

63 Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility

Grotjahn, D. A.; Chowdhury, S.; Xu, Y.; McKenney, R. J.; Schroer, T.; Lander, G.

10.1101/182576 — cell biology — Posted on 2017-08-31

64 Neurexin and Neuroligin-based adhesion complexes drive axonal arborisation growth independent of synaptic activity

Constance, W. D.; Mukherjee, A.; Fisher, Y. E.; Pop, S.; Blanc, E.; Toyama, Y.; Williams, D. W.

10.1101/182808 — neuroscience — Posted on 2017-08-31

65 Mapping DNA damage-dependent genetic interactions in yeast via orgy mating and barcode fusion genetics

Diaz-Mejia, J. J.; Mellor, J. C.; Cote, A.; Balint, A.; Ho, B.; Bansal, P.; Shaeri, F.; Gebbia, M.; Weile, J.; Verby, M.; Karkhanina, A.; Zhang, Y.; Wong, C.; Rich, J.; Prendergast, D.; Gupta, G.; Ozturk, S.; Durocher, D.; Brown, G. W.; Roth, F. P.

10.1101/181750 — systems biology — Posted on 2017-08-31

66 Minor spliceosome inactivation in the developing mouse cortex causes self-amplifying radial glial cell death and microcephaly.

Baumgartner, M.; Olthof, A. M.; Hyatt, K. C.; Lemoine, C.; Drake, K.; Sturrock, N.; Nguyen, N.; Al Seesi, S.; Kanadia, R. N.

10.1101/182816 — developmental biology — Posted on 2017-08-31

67 Dew-induced transpiration suppression impacts the water and isotope balances of Colocasia leaves

Gerlein-Safdi, C.; Gauthier, P. P. G.; Caylor, K. K.

10.1101/178293 — plant biology — Posted on 2017-08-30

68 Preferential cholinergic excitation of corticopontine neurons

Baker, A. L.; O'Toole, R. J.; Gulledge, A. T.

10.1101/182667 — neuroscience — Posted on 2017-08-30

69 Enhancer connectome in primary human cells reveals target genes of disease-associated DNA elements

Mumbach, M. R.; Satpathy, A. T.; Boyle, E. A.; Dai, C.; Gowen, B. G.; Cho, S. W.; Nguyen, M. L.; Rubin, A. J.; Granja, J. M.; Kazane, K. R.; Wei, Y.; Nguyen, T.; Greenside, P. G.; Corces, M. R.; Tycko, J.; Simeonov, D. R.; Suliman, N.; Li, R.; Xu, J.; Flynn, R. A.; Kundaje, A.; Khavari, P. A.; Marson, A.; Corn, J. E.; Quertermous, T.; Greenleaf, W. J.; Chang, H. Y.

10.1101/178269 — genomics — Posted on 2017-08-30

70 Discovering genetic interactions bridging pathways in genome-wide association studies

Fang, G.; Wang, W.; Paunic, V.; Heydari, H.; Costanzo, M.; Liu, X.; Liu, X.; Oately, B.; Steinbach, M.; Van Ness, B.; Schadt, E. E.; Pankratz, N. D.; Boone, C.; Kumar, V.; Myers, C. L.

10.1101/182741 — genetics — Posted on 2017-08-30

71 Molecular Analysis of Parasites in the Choreocolacaceae (Rhodophyta) Reveals a Reduced Harveyella mirabilis Plastid Genome and Supports the Transfer of Genera to the Rhodomelaceae (Rhodophyta)

Salomaki, E. D.; Saunders, G. W.; Lane, C. E.

10.1101/182709 — evolutionary biology — Posted on 2017-08-30

72 Geographic variation in sleep and metabolic function is associated with latitude and temperature

Brown, E.; Torres, J.; Bennick, R. A.; Rozzo, V.; Kerbs, A.; DiAngelo, J. R.; Keene, A.

10.1101/182790 — ecology — Posted on 2017-08-30

73 TRIP6 inhibits the Hippo signaling pathway in response to tension at adherens junctions

Dutta, S.; Mana-Capelli, S.; Paramasivam, M.; Dasgupta, I.; Cirka, H.; Billiar, K.; McCollum, D.

10.1101/182204 — cell biology — Posted on 2017-08-30

74 Early alterations of social brain networks in young children with autism

Sperdin, H. F.; Coito, A.; Kojovic, N.; Rihs, T. A.; Jan, R. K.; Franchini, M.; Plomp, G.; Vulliemoz, S.; Eliez, S.; Michel, C. M.; Schaer, M.

10.1101/180703 — neuroscience — Posted on 2017-08-30

75 AFQ-Browser: Supporting reproducible human neuroscience research through browser-based visualization tools

Yeatman, J. D.; Richie-Halford, A.; Smith, J. K.; Rokem, A.

10.1101/182402 — neuroscience — Posted on 2017-08-30

76 The modulation of neural gain facilitates a transition between functional segregation and integration in the brain

Shine, J. M.; Aburn, M. J.; Breakspear, M.; Poldrack, R. A.

10.1101/182444 — neuroscience — Posted on 2017-08-30

77 Serial quantification of brain oxygenation in acute stroke using streamlined-qBOLD

Stone, A. J.; Harston, G. W. J.; Carone, D.; Okell, T. W.; Kennedy, J.; Blockley, N. P.

10.1101/140897 — neuroscience — Posted on 2017-08-30

78 Preferential cholinergic excitation of corticopontine neurons

Gulledge, A. T.; Baker, A. L.; O'Toole, R. J.

10.1101/182667 — neuroscience — Posted on 2017-08-30

79 Structural and functional diversity of a dense sample of retinal ganglion cells

10.1101/182758 — neuroscience — Posted on 2017-08-30

80 Transcriptional Architecture of Synaptic Communication Delineates Cortical GABAergic Neuron Identity

Paul, A.; Crow, M.; Raudales, R.; Gillis, J.; Huang, Z. J.

10.1101/180034 — neuroscience — Posted on 2017-08-30

81 HPeV-3 predominated among Parechovirus A positive infants in the summer of 2013-2014 in Queensland, Australia.

McNeale, D. M.; Wang, C. Y. T.; Arden, K. E.; Mackay, I. M.

10.1101/182436 — microbiology — Posted on 2017-08-30

82 Elucidating the genetic architecture of reproductive ageing in the Japanese population

Horikoshi, M.; Day, F.; Kamatani, Y.; Hirata, M.; Akiyama, M.; Matsuda, K.; Wright, H.; Toro, C.; Ojeda, S.; Lomniczi, A.; Kubo, M.; Ong, K.; Perry, J.

10.1101/182717 — genetics — Posted on 2017-08-30

83 Selection-like biases emerge in population models with recurrent jackpot events

Hallatschek, O.

10.1101/182519 — evolutionary biology — Posted on 2017-08-30

84 Ancient symbiosis confers desiccation resistance to stored grain pest beetles

Engl, T.; Eberl, N.; Gorse, C.; Krueger, T.; Schmidt, T. H.- P.; Plarre, R.; Adler, C.; Kaltenpoth, M.

10.1101/182725 — evolutionary biology — Posted on 2017-08-30

85 Co-mutation and exclusion analysis in human tumors, a means for cancer biology studies and treatment design

Ochoa, S.; Martinez-Perez, E.; Zea, D. J.; Molina-Vila, M. A.; Marino-Buslje, C.

10.1101/182501 — cancer biology — Posted on 2017-08-30

86 Pan-cancer screen for mutations in non-coding elements with conservation and cancer specificity reveals correlations with expression and survival

Hornshoj, H.; Nielsen, M. M.; Sinnott-Armstrong, N. A.; Switnicki, M. P.; Rasmussen, M. J.; Madsen, T.; Sallari, R.; Kellis, M.; Orntoft, T.; Hobolth, A.; Pedersen, J. S.

10.1101/182642 — cancer biology — Posted on 2017-08-30

87 Quantitation of brain tumour microstructure response to Temozolomide therapy using non-invasive VERDICT MRI

Roberts, T. A.; Hyare, H.; Agliardi, G.; Hipwell, B.; d'Esposito, A.; Ianus, A.; Breen-Norris, J. O.; Ramasawmy, R.; Taylor, V.; Atkinson, D.; Punwani, S.; Lythgoe, M. F.; Siow, B.; Brandner, S.; Rees, J.; Panagiotaki, E.; Alexander, D. C.; Walker-Samuel, S.

10.1101/182675 — biophysics — Posted on 2017-08-30

88 Skin biomarkers for cystic fibrosis: a potential noninvasive approach for patient screening.

Esteves, C. Z.; Dias, L. A.; Lima, E. O.; Noin de Oliveira, D.; Melo, C. F. O. R.; Gomez, C. C. S.; Ribeiro, J. D.; Ribeiro, A. F.; Levy, C. E.; Catharino, R. R.

10.1101/182733 — biochemistry — Posted on 2017-08-30

89 A Mathematical Model of the Phosphoinositide Pathway

Olivenca, D. V.; Uliyakina, I.; Fonseca, L. L.; Amaral, M.; Voit, E.; Pinto, F. R.

10.1101/182634 — systems biology — Posted on 2017-08-30

90 Novel Computed Tomography-based tools reliably quantify plant reproductive investment

Staedler, Y. M.; Kreisberger, T.; Manafzadeh, S.; Chartier, M.; Handschuh, S.; Pamperl, S.; Sontag, S.; Paun, O.; Schoenenberger, J.

10.1101/182386 — plant biology — Posted on 2017-08-30

91 Inhibition of granulocyte ROS production by opioids prevents regeneration

Labit, E.; Rabiller, L.; Guissard, C.; Andre, M.; Rampon, C.; Barreau, C.; Cousin, B.; Carriere, A.; Raffin, M.; Mithieux, G.; Ala Eddine, M.; Pipy, B.; Lorsignol, A.; Vriz, S.; Dromard, C.; Casteilla, L.

10.1101/182584 — physiology — Posted on 2017-08-30

92 Neurons in primate entorhinal cortex represent gaze position in multiple spatial reference frames

Meister, M. L. R.; Buffalo, E. A.

10.1101/182220 — neuroscience — Posted on 2017-08-30

93 Posterior parietal cortex represents sensory stimulus history and is necessary for its effects on behavior

Akrami, A.; Kopec, C. D.; Diamond, M. E.; Brody, C. D.

10.1101/182246 — neuroscience — Posted on 2017-08-30

94 Mechanical Activation Of Piezo1 But Not Nav1.2 Channels By Ultrasound

Prieto, M. L.; Firouzi, K.; Khuri-Yakub, B. T.; Maduke, M.

10.1101/136994 — neuroscience — Posted on 2017-08-30

95 Drosophila neural stem cells are polarized by their daughter cells

Loyer, N.; Januschke, J.

10.1101/182592 — cell biology — Posted on 2017-08-30

96 DNA methylation profiling of breast cancer cell lines along the epithelial mesenchymal spectrum - implications for the choice of circulating tumour DNA methylation markers

Viet-Phuong Le, A.; Szaumkessel, M.; Tan, T. Z.; Thiery, J.-P.; Thompson, E. W.; Dobrovic, A.

10.1101/182600 — cancer biology — Posted on 2017-08-30

97 Water-mediated interactions enable smooth substrate transport in a bacterial efflux pump

Vargiu, A. V.; Ramaswamy, V. K.; Malvacio, I.; Malloci, G.; Kleinekatöfer, U.; Ruggerone, P.

10.1101/182683 — biophysics — Posted on 2017-08-30

98 TiSAn: Estimating Tissue Specific Effects of Coding and Non-coding Variants

Vervier, K.; Michaelson, J. J.

10.1101/141408 — bioinformatics — Posted on 2017-08-30

99 Genome-wide profiling of transcribed enhancers during macrophage activation

Denisenko, E.; Guler, R.; Mhlanga, M.; Suzuki, H.; Brombacher, F.; Schmeier, S.

10.1101/163519 — bioinformatics — Posted on 2017-08-30

100 Deciphering Transcriptional Regulation of Human Core Promoters

Weingarten-Gabbay, S.; Nir, R.; Lubliner, S.; Sharon, E.; Kalma, Y.; Weinberger, A.; Segal, E.

10.1101/174904 — genomics — Posted on 2017-08-30

101 Coexistence of multiple endemic and pandemic lineages of the rice blast pathogen

Gladieux, P.; Ravel, S.; Rieux, A.; Cros-Arteil, S.; Adreit, H.; Milazzo, J.; Thierry, M.; Fournier, E.; Terauchi, R.; Tharreau, D.

10.1101/179895 — evolutionary biology — Posted on 2017-08-30

102 Gaussian decomposition of high-resolution melt curve derivatives for measuring genome-editing efficiency

Zaboikin, M.; Freter, C.; Srinivasakumar, N.

10.1101/176719 — bioengineering — Posted on 2017-08-30

103 Forecasting crowd dynamics through coarse-grained data analysis

Motsch, S.; Moussaid, M.; Guillot, E. G.; Moreau, M.; Pettre, J.; Theraulaz, G.; Appert-Rolland, C.; Degond, P.

10.1101/175760 — animal behavior and cognition — Posted on 2017-08-30

104 Random Walk With Restart On Multiplex And Heterogeneous Biological Networks

Valdeolivas, A.; Tichit, L.; Navarro, C.; Perrin, S.; Odelin, G.; Levy, N.; Cau, P.; Remy, E.; Baudot, A.

10.1101/134734 — systems biology — Posted on 2017-08-30

105 The Mouse Cortical Connectome Characterized by an Ultra Dense Cortical Graph Maintains Specificity by Distinct Connectivity Profiles

Gamanut, R.; Kennedy, H.; Toroczkai, Z.; Van Essen, D.; Knoblauch, K.; Burkhalter, A.

10.1101/156976 — neuroscience — Posted on 2017-08-30

106 Light Sheet Theta Microscopy for High-resolution Quantitative Imaging of Large Biological Systems

Migliori, B.; Datta, M. S.; Dupre, C.; Apak, M. C.; Asano, S.; Gao, R.; Boyden, E. S.; Hermanson, O.; Yuste, R.; Tomer, R.

10.1101/119289 — neuroscience — Posted on 2017-08-30

107 Fear extinction requires infralimbic cortex projections to the basolateral amygdala

Bloodgood, D. W.; Sugam, J. A.; Holmes, A.; Kash, T. L.

10.1101/172791 — neuroscience — Posted on 2017-08-30

108 Macrophage-to-sensory neuron crosstalk mediated by Angiotensin II type-2 receptor elicits neuropathic pain

Shepherd, A. J.; Mickle, A. D.; Copits, B. A.; Karlsson, P.; Kadunganattil, S.; Golden, J. P.; Tadinada, S. M.; Mack, M. R.; Haroutounian, S.; de Kloet, A. D.; Samineni, V. K.; Valtcheva, M. V.; McIlvried, L. A.; Sheahan, T. D.; Jain, S.; Ray, P. R.; Usachev, Y. M.; Dussor, G.; Kim, B. S.; Krause, E. G.; Price, T. J.; Gereau, R. W.; Mohapatra, D. P.

10.1101/166546 — neuroscience — Posted on 2017-08-30

109 EVOLUTIONARY ANALYSIS OF CANDIDATE NON-CODING ELEMENTS REGULATING NEURODEVELOPMENTAL GENES IN VERTEBRATES

Novo, F. J.

10.1101/150482 — evolutionary biology — Posted on 2017-08-30

110 Extinction Rates In Tumor Public Goods Games

Gerlee, P.; Altrock, P. M.

10.1101/134361 — cancer biology — Posted on 2017-08-30

111 The evolutionary history of 2,658 cancers

Gerstung, M.; Jolly, C.; Leshchiner, I.; Dentro, S. C.; Gonzalez, S.; Mitchell, T. J.; Rubanova, Y.; Anur, P.; Rosebrock, D.; Yu, K.; Tarabichi, M.; Deshwar, A.; Wintersinger, J.; Kleinheinz, K.; Vazquez-Garcia, I.; Haase, K.; Sengupta, S.; Macintyre, G.; Malikic, S.; Donmez, N.; Livitz, D. G.; Cmero, M.; Demeulemeester, J.; Schumacher, S.; Fan, Y.; Yao, X.; Lee, J.; Schlesner, M.; Boutros, P. C.; Bowtell, D. D.; Zhu, H.; Getz, G.; Imielinski, M.; Beroukhim, R.; Sahinalp, S. C.; Ji, Y.; Peifer, M.; Markowetz, F.; Mustonen, V.; Yuan, K.; Wang, W.; Morris, Q. D.; Spellman, P. T.; Wedge, D. C.; V

10.1101/161562 — cancer biology — Posted on 2017-08-30

112 DNAlogo: a smart mini application for generating DNA sequence logos

GUO, Y.

10.1101/096933 — bioinformatics — Posted on 2017-08-30

113 A bestiary of localized sequence rearrangements in human DNA

Frith, M.; Khan, S.

10.1101/175943 — bioinformatics — Posted on 2017-08-30

114 Imaging specific cellular glycan structures using glycosyltransferases via click chemistry

Wu, Z.; Person, A.; Anderson, M.; Burroughs, B.; Tatge, T.; Zou, Y.; Wang, L.; Geders, T.; Sackstein, R.

10.1101/181453 — molecular biology — Posted on 2017-08-30

115 Synergy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Inhibiting P. aeruginosa Quorum Sensing

Fong, J.; Zhang, C.; Yang, R.; Boo, Z. Z.; Tan, S. K.; Nielsen, T. E.; Givskov, M.; Wu, B.; Su, H.; Yang, L.

10.1101/182543 — microbiology — Posted on 2017-08-30

116 SuperDCA for genome-wide epistasis analysis

Puranen, S.; Pesonen, M.; Pensar, J.; Xu, Y. Y.; Lees, J. A.; Bentley, S. D.; Croucher, N. J.; Corander, J.; Aurell, E.

10.1101/182527 — genomics — Posted on 2017-08-30

117 Generation, selection and transcriptomic profiling of human neuromesodermal and spinal cord progenitors in vitro

Verrier, L.; Davidson, L.; Gierlinski, M.; Storey, K. G.

10.1101/182279 — developmental biology — Posted on 2017-08-30

118 A novel VPS33A interaction motif is a master-switch controlling the inhibition and promotion of mammalian Stx17 interactions with SNAP29 and VAMP7 during autophagy

Saleeb, R. S.; Kavanagh, D. M.; Dun, A. R.; Dalgarno, P. A.; Duncan, R. R.

10.1101/182626 — cell biology — Posted on 2017-08-30

119 Resolution of Reprogramming Transition States by Single Cell RNA-Sequencing

Guo, L.; Wang, X.; Gao, M.; Lin, L.; Kuang, J.; Mai, Y.; Wu, F.; Liu, H.; Yang, J.; Chu, S.; Song, H.; Liu, Y.; Liu, J.; Wang, J.; Pan, G.; Hutchins, A. P.; Liu, J.; Chen, J.; Pei, D.

10.1101/182535 — cell biology — Posted on 2017-08-30

120 Phosphatase PP2A and microtubule pulling forces disassemble centrosomes during mitotic exit

Enos, S. J.; Dressler, M.; Ferreira Gomes, B.; Hyman, A. A.; Woodruff, J. B.

10.1101/182618 — cell biology — Posted on 2017-08-30

121 PrimerServer: a high-throughput primer design and specificity-checking platform

Zhu, T.; Liang, C.; Meng, Z.; Li, Y.; Wu, Y.; Guo, S.; Zhang, R.

10.1101/181941 — bioinformatics — Posted on 2017-08-30

122 ApoplastP: prediction of effectors and plant proteins in the apoplast using machine learning

Sperschneider, J.; Dodds, P. N.; Singh, K. B.; Taylor, J. M.

10.1101/182428 — bioinformatics — Posted on 2017-08-30

123 Phylogenetic approaches to identifying fragments of the same gene, with application to the wheat genome

Pilizota, I.; Redestig, H.; Dessimoz, C.

10.1101/182550 — bioinformatics — Posted on 2017-08-30

124 Neurons in primate entorhinal cortex represent gaze position in multiple spatial reference frames

Meister, M. L. R.; Buffalo, E. A.

10.1101/182220 — neuroscience — Posted on 2017-08-30

125 Novel Quantitative ChIP-seq Methods Measure Absolute Fold-Change in ER Binding Upon Fulvestrant Treatment

Guertin, M. J.; Markowetz, F.; Holding, A. N.

10.1101/182261 — genomics — Posted on 2017-08-30

126 Inevitability of the emergence and persistence of genetic parasites caused by thermodynamic instability of parasite-free states

Koonin, E. V.; Wolf, Y. I.; Katsnelson, M. I.

10.1101/182410 — evolutionary biology — Posted on 2017-08-30

127 Towards physical principles of biological evolution

Katsnelson, M. I.; Wolf, Y. I.; Koonin, E. V.

10.1101/182378 — evolutionary biology — Posted on 2017-08-30

128 Communication from learned to innate olfactory processing centers is required for memory retrieval in Drosophila

Dolan, M.-J.; Belliart-Guerin, G.; Bates, A. S.; Aso, Y.; Frechter, S.; Roberts, R. J. V.; Schlegel, P.; Wong, A.; Hammad, A.; Bock, D.; Rubin, G. M.; Preat, T.; Placais, P.-Y.; Jefferis, G. S. X. E.

10.1101/167312 — neuroscience — Posted on 2017-08-29

129 A "Tug of War" maintains a dynamic protein-membrane complex: MD simulations of C-Raf RBD-CRD bound to K-Ras4B at an anionic membrane

LI, Z.; Prakash, P.; Buck, M.

10.1101/181347 — biophysics — Posted on 2017-08-29

130 Drug discovery to counteract antinociceptive tolerance with mu-opioid receptor endocytosis

Chao, P.-K.; Ke, Y.-Y.; Chang, H.-F.; Huang, Y.-H.; Ou, L.-C.; Chuang, J.-Y.; Lin, Y.-C.; Lee, P.-T.; Chang, W.-T.; Chen, S.-C.; Ueng, S.-H.; Hsu, J. T.-A.; Tao, P.-L.; Law, P.-Y.; Loh, H. H.; Shih, C.; Yeh, S.-H.

10.1101/182360 — neuroscience — Posted on 2017-08-29

131 Covert Shift of Attention Modulates the Value Encoding in the Orbitofrontal Cortex

Xie, Y.; Nie, C.; Yang, T.

10.1101/181784 — neuroscience — Posted on 2017-08-29

132 Network structure of the human musculoskeletal system shapes neural interactions on multiple timescales

Kerkman, J. N.; Daffertshofer, A.; Gollo, L.; Breakspear, M.; Boonstra, T. W.

10.1101/181818 — neuroscience — Posted on 2017-08-29

133 The impact of persistent bacterial bronchitis on the pulmonary microbiome of children

Cuthbertson, L.; Craven, V.; Bingle, L.; Cookson, W. O. C. M.; Everard, M. L.; Moffatt, M. F.

10.1101/181982 — genomics — Posted on 2017-08-29

134 Full likelihood inference from the site frequency spectrum based on the optimal tree resolution

Sainudiin, R.; Veber, A.

10.1101/181412 — genetics — Posted on 2017-08-29

135 Human demographic history has amplified the effects background selection across the genome

Torres, R.; Szpiech, Z. A.; Hernandez, R. D.

10.1101/181859 — evolutionary biology — Posted on 2017-08-29

136 Demographic consequences of invasion by a native, controphic competitor to an insular bird population

Johnson, K. M.; Germain, R. R.; Tarwater, C. E.; Arcese, P.

10.1101/182352 — ecology — Posted on 2017-08-29

137 Taxon sampling unequally affects individual nodes in a phylogenetic tree: consequences for model gene tree construction in SwissTree

Boeckmann, B.; Dylus, D.; Moretti, S.; Altenhoff, A.; Train, C.-M.; Kriventseva, E.; Bougueleret, L.; Xenarios, I.; Privman, E.; Dessimoz, C.

10.1101/181966 — bioinformatics — Posted on 2017-08-29

138 Identifying weak signals in inhomogeneous neuronal images for large-scale tracing of neurites

Li, S.; Quan, T.; Zhou, H.; Yin, F.; Li, A.; Fu, L.; Luo, Q.; Gong, H.; Zeng, S.

10.1101/181867 — bioinformatics — Posted on 2017-08-29

139 BLAST-based validation of metagenomic sequence assignments

Bazinet, A. L.; Ondov, B. D.; Sommer, D. D.; Ratnayake, S.

10.1101/181636 — bioinformatics — Posted on 2017-08-29

140 GenomeDISCO: A concordance score for chromosome conformation capture experiments using random walks on contact map graphs

Ursu, O.; Boley, N.; Taranova, M.; Wang, Y. X. R.; Yardimci, G. G.; Noble, W. S.; Kundaje, A.

10.1101/181842 — bioinformatics — Posted on 2017-08-29

141 An individual differences approach to semantic cognition: Divergent effects of age on representation, retrieval and selection

Hoffman, P.

10.1101/182170 — neuroscience — Posted on 2017-08-29

142 Mouse hepatitis virus nsp14 exoribonuclease activity is required for resistance to innate immunity

Case, J. B.; Li, Y.; Elliott, R.; Lu, X.; Graepel, K. W.; Sexton, N. R.; Smith, E. C.; Weiss, S. R.; Denison, M. R.

10.1101/182196 — microbiology — Posted on 2017-08-29

143 Ecophylogenetics Reveals the Evolutionary Associations between Mammals and their Gut Microbiota

Gaulke, C. A.; Arnold, H. K.; Kembel, S. W.; O'Dwyer, J. P.; Sharpton, T. J.

10.1101/182212 — microbiology — Posted on 2017-08-29

144 CXCR4 involvement in neurodegenerative diseases

Bonham, L; Karch, C; Fan, C; Tan, C; Geier, E; Wang, Y; Wen, N; Broce, I; Li, Y; Barkovich, M; Ferrari, R; Hardy, J; Momeni, P; Höeglinger, G; Müller, U; Hess, C; Sugrue, L; Dillon, W; Schellenberg, G; Miller, B; Andreassen, O; Dale, A; Barkovich, A; Yokoyama, J; Desikan, R

10.1101/181693 — genetics — Posted on 2017-08-29

145 Kafka interfaces for composable streaming genomics pipelines

Versaci, F.; Pireddu, L.; Zanetti, G.

10.1101/182030 — bioinformatics — Posted on 2017-08-29

146 Peptide Pattern Recognition for high-throughput protein sequence analysis and clustering

Busk, P. K.

10.1101/181917 — bioinformatics — Posted on 2017-08-29

147 Posterior parietal cortex represents sensory stimulus history and is necessary for its effects on behavior

Akrami, A.; Kopec, C. D.; Diamond, M. E.; Brody, C. D.

10.1101/182246 — neuroscience — Posted on 2017-08-29

148 Deep grey matter volume loss drives disability worsening in multiple sclerosis

Eshaghi, A.; Prados, F.; Brownlee, W.; Altmann, D. R.; Tur, C.; Cardoso, M. J.; De Angelis, F.; van de Pavert, S. H.; Cawley, N.; De Stefano, N.; Stromillo, M. L.; Battaglini, M.; Ruggieri, S.; Gasperini, C.; Filippi, M.; Rocca, M. A.; Rovira, A.; Sastre-Garriga, J.; Vrenken, H.; Leurs, C. E.; Killestein, J.; Pirpamer, L.; Enzinger, C.; Ourselin, S.; Wheeler-Kingshott, C. A. M. G.; Chard, D.; Thompson, A. J.; Alexander, D. C.; Barkhof, F.; Ciccarelli, O.

10.1101/182006 — neuroscience — Posted on 2017-08-29

149 Functional characterization of 3D-protein structures informed by human genetic diversity

Hicks, M.; Bartha, I.; di Iulio, J.; Abagyan, R.; Venter, J. C.; Telenti, A.

10.1101/182287 — genomics — Posted on 2017-08-29

150 Tripolar mitosis drives the association between maternal genotypes of PLK4 and aneuploidy in human preimplantation embryos

McCoy, R. C.; Newnham, L. J.; Ottolini, C. S.; Hoffmann, E. R.; Chatzimeletiou, K.; Cornejo, O. E.; Zhan, Q.; Zaninovic, N.; Rosenwaks, Z.; Petrov, D. A.; Demko, Z. P.; Sigurjonsson, S.; Handyside, A. H.

10.1101/182303 — genetics — Posted on 2017-08-29

151 Exome sequencing and genotyping identify a rare variant in NLRP7 gene associated with ulcerative colitis.

Onoufriadis, A.; Stone, K.; Katsiamides, A.; Amar, A.; Omar, Y.; de Lange, K.; Taylor, K. M.; Barrett, J.; Pollok, R.; Hayee, B.; Mansfield, J. C.; Sanderson, J. D.; Simpson, M. A.; Mathew, C. G.; Prescott, N.

10.1101/182113 — genetics — Posted on 2017-08-29

152 A rare missense mutation in MYH6 confers high risk of coarctation of the aorta

Bjornsson, T.; Thorolfsdottir, R. B.; Sveinbjornsson, G.; Sulem, P.; Norddahl, G. L.; Helgadottir, A.; Gretarsdottir, S.; Magnusdottir, A.; Danielsen, R.; Sigurdsson, E. L.; Adalsteinsdottir, B.; Gunnarsson, S. I.; Jonsdottir, I.; Arnar, D. O.; Helgason, H.; Gudbjartsson, T.; Gudbjartsson, D. F.; Thorsteinsdottir, U.; Holm, H.; Stefansson, K.

10.1101/180794 — genetics — Posted on 2017-08-29

153 "Protoribosome" as new game of life

Demongeot, J.

10.1101/182055 — evolutionary biology — Posted on 2017-08-29

154 Cheater-altruist synergy in immunopathogenic ecological public goods games

Morsky, B.; Vural, D.

10.1101/182162 — ecology — Posted on 2017-08-29

155 Mechanical mapping of spinal cord development and repair in living zebrafish larvae using Brillouin microscopy

Schlüssler, R.; Möllmert, S.; Abuhattum, S.; Möckel, C.; Zimmermann, C.; Czarske, J.; Guck, J.

10.1101/181560 — biophysics — Posted on 2017-08-29

156 Topology and cooperative stability: the two master regulators of protein half-life in the cell

Mallik, S.; Kundu, S.

10.1101/181925 — biophysics — Posted on 2017-08-29

157 GVC: A superfast and universal genomic variant caller

Zhang, Z.; Yin, L.; Cao, L.; Liu, C.; Hao, L.; Ling, S.

10.1101/182089 — bioinformatics — Posted on 2017-08-29

158 Single-shot super-resolution total internal reflection fluorescence microscopy

Guo, M.; Chandris, P.; Giannini, J. P.; Trexler, A. J.; Fischer, R.; Chen, J.; Vishwasrao, H. D.; Rey-Suarez, I.; Wu, Y.; Waterman, C. M.; Patterson, G. H.; Upadhyaya, A.; Taraska, J.; Shroff, H.

10.1101/182121 — bioengineering — Posted on 2017-08-29

159 On the Structure and Mechanism of Two-Pore Channels

Kintzer, A. F.; Stroud, R.

10.1101/181578 — biochemistry — Posted on 2017-08-29

160 Fishing for New Bt Receptors in Diamondback Moth

Chen, Y.; Huang, Y.; Liu, Q.; Xu, J.; Hogenhout, S.; Huang, Y.; Tan, A.

10.1101/181834 — biochemistry — Posted on 2017-08-29

161 Photoperiodic control of the Arabidopsis proteome reveals a translational coincidence mechanism

Seaton, D.; Graf, A.; Baerenfaller, K.; Stitt, M.; Millar, A.; Gruissem, W.

10.1101/182071 — plant biology — Posted on 2017-08-29

162 Defining the synaptic mechanisms that tune CA3-CA1 reactivation during sharp-wave ripples

Malerba, P.; Jones, M. W.; Bazhenov, M.

10.1101/164699 — neuroscience — Posted on 2017-08-29

163 Human macrophages survive and adopt activated genotypes in living zebrafish

Paul, C. D.; Devine, A.; Bishop, K.; Xu, Q.; Daly, K. M.; Lewis, C.; Green, D. S.; Staunton, J. R.; Choksi, S.; Liu, Z.-G.; Sood, R.; Tanner, K.

10.1101/181685 — developmental biology — Posted on 2017-08-29

164 A Portable Software Library that Implements the Gillespie Direct Method

Sauro, H. M.

10.1101/181446 — systems biology — Posted on 2017-08-29

165 Vegetative compatibility groups explain variation in the virulence of Verticillium dahliae on strawberry

Fan, R.; Cockerton, H.; Armitage, A. D.; Bates, H.; Cascant-Lopez, E.; Antanaviciute, L.; Xu, X.; Hu, X.; Harrison, R. J.

10.1101/181172 — plant biology — Posted on 2017-08-29

166 The neural representation of personally familiar and unfamiliar faces in the distributed system for face perception

Visconti di Oleggio Castello, M.; Halchenko, Y. O.; Guntupalli, J. S.; Gors, J. D.; Gobbini, M. I.

10.1101/138297 — neuroscience — Posted on 2017-08-29

167 Your favorite color makes learning more precise and adaptable

Farashahi, S.; Rowe, K.; Aslami, Z.; Lee, D.; Soltani, A.

10.1101/097741 — neuroscience — Posted on 2017-08-29

168 Dominance of ST131 Escherichia coli carrying blaCTX-M in patients with bloodstream infections caused by cephalosporin-resistant strains in Australia, New Zealand and Singapore: whole genome analysis of isolates from a randomised trial

Harris, P.; Ben Zakour, N.; Roberts, L. W.; Wailan, A. M.; Zowawi, H. M.; Tambyah, P. A.; Lye, D. C.; Jureen, R.; Lee, T. H.; Izharuddin, E.; Yin, M.; Looke, D.; Runnegar, N.; Rogers, B.; Bhally, H.; Crowe, A.; Schembri, M. A.; Beatson, S.; Paterson, D. L.

10.1101/181768 — microbiology — Posted on 2017-08-29

169 Anaerobic methanotrophic communities thrive in deep submarine permafrost

Winkel, M.; Mitzscherling, J.; Overduin, P. P.; Horn, F.; Winterfeld, M.; Rijkers, R.; Grigoriev, M. N.; Knoblauch, C.; Mangelsdorf, K.; Wagner, D.; Liebner, S.

10.1101/181891 — microbiology — Posted on 2017-08-29

170 Gene co-expression networks in whole blood implicate multiple interrelated molecular pathways in obese asthma

Croteau-Chonka, D. C.; Chen, Z.; Barnes, K. C.; Barraza-Villarreal, A.; Celedon, J. C.; Gauderman, W. J.; Gilliland, F. D.; Krishnan, J. A.; Liu, A. H.; London, S. J.; Martinez, F. D.; Millstein, J.; Naureckas, E. T.; Nicolae, D. L.; White, S. R.; Ober, C.; Weiss, S. T.; Raby, B. A.

10.1101/181651 — genomics — Posted on 2017-08-29

171 Mitochondrial sirtuins sir-2.2 and sir-2.3 regulate lifespan in C. elegans

Chang, S. M.; McReynolds, M. R.; Hanna-Rose, W.

10.1101/181727 — genetics — Posted on 2017-08-29

172 A Caenorhabditis elegans model of adenylosuccinate lyase deficiency reveals neuromuscular and reproductive phenotypes of distinct etiology

Fenton, A. R.; Janowitz, H. N.; McReynolds, M. R.; Wang, W.; Hanna-Rose, W.

10.1101/181719 — genetics — Posted on 2017-08-29

173 Hemimetabolous genomes reveal molecular basis of termite eusociality

Harrison, M. C.; Jongepier, E.; Robertson, H. M.; Arning, N.; Bitard-Feildel, T.; Chao, H.; Childers, C. P.; Dinh, H.; Doddapaneni, H.; Dugan, S.; Gowin, J.; Greiner, C.; Han, Y.; Hu, H.; Hughes, D. S. T.; Huylmans, A.-K.; Kemena, C.; Kremer, L. P. M.; Lee, S. L.; Lopez-Ezquerra, A.; Mallet, L.; Monroy-Kuhn, J. M.; Moser, A.; Murali, S. C.; Muzny, D. M.; Otani, S.; Piulachs, M.-D.; Poelchau, M.; Qu, J.; Schaub, F.; Wada-Katsumata, A.; Worley, K. C.; Xie, Q.; Ylla, G.; Poulsen, M.; Gibbs, R. A.; Schal, C.; Richards, S.; Belles, X.; Korb, J.; Bornberg-Bauer, E.

10.1101/181909 — evolutionary biology — Posted on 2017-08-29

174 BITE: an R package for biodiversity analyses

Milanesi, M.; Capomaccio, S.; Vajana, E.; Bomba, L.; Garcia, J. F.; Ajmone-Marsan, P.; Colli, L.

10.1101/181610 — bioinformatics — Posted on 2017-08-29

175 A high-throughput analysis method of microdroplet PCR coupled with fluorescence spectrophotometry

Du, Y.; Zhao, X.; Zhao, B.; Xu, Y.; Shi, W.; Ren, F.; Wu, Y.; Hu, R.; Fan, X.; Zhang, Q.; Zhang, X.; Shi, B.; Zhao, H.; Zhao, K.

10.1101/181974 — biochemistry — Posted on 2017-08-29

176 Fast and Simple Tool for the Quantification of Biofilm-Embedded Cells Sub-Populations From Fluorescent Microscopic Images

Bogachev, M.; Markelov, O.; Trizna, E.; Baydamshina, D.; Zelenikhin, P.; Murtazina, R.; Kayumov, A.

10.1101/181495 — microbiology — Posted on 2017-08-29

177 A High HIV-1 Strain Variability in London, UK, Revealed by Full-Genome Analysis: Results from the ICONIC Project

Yebra, G.; Frampton, D.; Gallo Cassarino, T.; Raffle, J.; Hubb, J.; Ferns, B.; Kozlakidis, Z.; Hayward, A.; Kellam, P.; Pillay, D.; Clark, D.; Nastouli, E.; Leigh Brown, A. J.

10.1101/139642 — genomics — Posted on 2017-08-29

178 The Past Sure Is Tense: On Interpreting Phylogenetic Divergence Time Estimates

Brown, J. W.; Smith, S. A.

10.1101/113720 — evolutionary biology — Posted on 2017-08-29

179 Optical Coherence Tomography Reveals Mechanobiologically Stable Self-Organizing Di-Fork Architecture of Mice Cutaneous Scars

Ghosh, B.; Mandal, M.; Mitra, P.; Chatterjee, J.

10.1101/181545 — biophysics — Posted on 2017-08-29

180 Parallel sequencing lives, or what makes large sequencing projects successful

Quilez, J.; Vidal, E.; Le Dily, F.; Serra, F.; Cuartero, Y.; Stadhouders, R.; Graf, T.; Marti-Renom, M. A.; Beato, M.; Filion, G.

10.1101/136358 — bioinformatics — Posted on 2017-08-29

181 Precursor processes of human self-initiated action

Khalighinejad, N.; Schurger, A.; Desantis, A.; Zmigrod, L.; Haggard, P.

10.1101/120105 — neuroscience — Posted on 2017-08-29

182 Activations of Deep Convolutional Neural Network are Aligned with Gamma Band Activity of Human Visual Cortex

Kuzovkin, I.; Vicente, R.; Petton, M.; Lachaux, J.-P.; Baciu, M.; Kahane, P.; Rheims, S.; Vidal, J. R.; Aru, J.

10.1101/133694 — neuroscience — Posted on 2017-08-29

183 Plant genes influence microbial hubs that shape beneficial leaf communities

Brachi, B.; Filiault, D.; Darme, P.; Le Mentec, M.; Kerdaffrec, E.; Rabanal, F.; Anastasio, A.; Box, M.; Duncan, S.; Morton, T.; Novikova, P.; Perisin, M.; Tsuchimatsu, T.; Woolley, R.; Yu, M.; Dean, C.; Nordborg, M.; Holm, S.; Bergelson, J.

10.1101/181198 — microbiology — Posted on 2017-08-29

184 GTC: a novel attempt to maintenance of huge genome collections compressed

Danek, A.; Deorowicz, S.

10.1101/131649 — bioinformatics — Posted on 2017-08-29

185 A flexible ontology for inference of emergent whole cell function from relationships between subcellular processes

Hansen, J.; Meretzky, D.; Woldesenbet, S.; Stolovitzky, G.; Iyengar, R.

10.1101/112201 — systems biology — Posted on 2017-08-28

186 A Rho-GTPase based model explains spontaneous collective migration of neural crest cell clusters

Merchant, B.; Edelstein-Keshet, L.; Feng, J.

10.1101/181743 — developmental biology — Posted on 2017-08-28

187 Human macrophages survive and adopt activated genotypes in living zebrafish

Paul, C. D.; Devine, A.; Bishop, K.; Xu, Q.; Daly, K. M.; Lewis, C.; Green, D. S.; Staunton, J. R.; Choski, S.; Liu, Z.-G.; Sood, R.; Tanner, K.

10.1101/181685 — developmental biology — Posted on 2017-08-28

188 Positive Feedback Between Contractile Ring Myosin and Ring-Directed Cortical Flow Drives Cytokinesis

Khaliullin, R.; Green, R.; Shi, L.; Berns, M.; Gomez-Cavazos, J. S.; Desai, A.; Oegema, K.

10.1101/161133 — cell biology — Posted on 2017-08-28

189 Activation of Somatostatin Inhibitory Neurons by Lypd6-nAChRα2 System Restores Juvenile-like Plasticity in Adult Visual Cortex

Sadahiro, M.; Demars, M. P.; Burman, P.; Yevoo, P.; Smith, M. R.; Zimmer, A.; Morishita, H.

10.1101/155465 — neuroscience — Posted on 2017-08-28

190 HiCcompare: a method for joint normalization of Hi-C datasets and differential chromatin interaction detection

Stansfield, J.; Dozmorov, M. G.

10.1101/147850 — bioinformatics — Posted on 2017-08-28

191 Time-resolved Interaction Proteomics of the Putative Scaffold Protein GIGANTEA in Arabidopsis thaliana

Krahmer, J.; Goralogia, G.; Kubota, A.; Johnson, R. S.; Song, Y. H.; Halliday, K.; MacCoss, M. J.; LeBihan, T.; Imaizumi, T.; Millar, A.

10.1101/162271 — plant biology — Posted on 2017-08-28

192 Frequency-specific neuromodulation of local and distant connectivity in aging & episodic memory function

Davis, S. W.; Luber, B.; Murphy, D. L. K.; Lisanby, S. H.; Cabeza, R.

10.1101/061267 — neuroscience — Posted on 2017-08-28

193 UNC-5 (UNC5) mediates neuronal outgrowth patterning in Caenorhabditis elegans by regulating UNC-40 (DCC) asymmetric localization

Limerick, G.; Tang, X.; Lee, W. S.; Mohamed, A.; Al-Aamiri, A.; Wadsworth, W. G.

10.1101/083436 — neuroscience — Posted on 2017-08-28

194 How Convincing Is A Matching Y-Chromosome Profile?

Andersen, M. M.; Balding, D. J.

10.1101/131920 — genetics — Posted on 2017-08-28

195 Functional effects of heating and cooling gene networks

Charlebois, D. A.; Hauser, K.; Marshall, S.; Balazsi, G.

10.1101/181537 — synthetic biology — Posted on 2017-08-28

196 Network Architecture and Mutational Sensitivity of the C. elegans Metabolome

Johnson, L. M.; Chandler, L. M.; Davies, S. K.; Baer, C. F.

10.1101/181511 — systems biology — Posted on 2017-08-28

197 Putting the "dynamic" back into dynamic functional connectivity

Heitmann, S.; Breakspear, M.

10.1101/181313 — neuroscience — Posted on 2017-08-28

198 On the relationship between instantaneous phase synchrony and correlation-based sliding windows for time-resolved fMRI connectivity analysis

Pedersen, M.; Omidvarnia, A.; Zalesky, A.; Jackson, G. D.

10.1101/179820 — neuroscience — Posted on 2017-08-28

199 Common features in plastic changes rather than constructed structures in recurrent neural network prefrontal cortex models

Kuroki, S.; Isomura, T.

10.1101/181297 — neuroscience — Posted on 2017-08-28

200 Fast and Simple Tool for the Quantification of Biofilm-Embedded Cells Sub-Populations From Fluorescent Microscopic Images

Bogachev, M.; Markelov, O.; Trizna, E.; Baydamshina, D.; Zelenikhin, P.; Murtazina, R.; Kayumov, A.

10.1101/181495 — microbiology — Posted on 2017-08-28

201 Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

Satizabal, C. L.; Adams, H. H. H.; Hibar, D. P.; White, C. C.; Stein, J. L.; Scholz, M.; Sargurupremraj, M.; Jahanshad, N.; Smith, A. V.; Bis, J. C.; Jian, X.; Luciano, M.; Hofer, E.; Teumer, A.; van der Lee, S. J.; Yang, J.; Yanek, L. R.; Lee, T. V.; Li, S.; Hu, Y.; Koh, J. Y.; Eicher, J. D.; Desrivieres, S.; Arias-Vasquez, A.; Chauhan, G.; Athanasiu, L.; Renteria, M. E.; Kim, S.; Hohn, D.; Armstrong, N. J.; Chen, Q.; Holmes, A. J.; den Braber, A.; Kloszewska, I.; Andersson, M.; Espeseth, T.; Grimm, O.; Abramovic, L.; Alhusaini, S.; Milaneschi, Y.; Papmeyer, M.; Axelsson, T.; Ehrlich, S.; Roi

10.1101/173831 — genetics — Posted on 2017-08-28

202 CRISPR-based Herd Immunity Limits Phage Epidemics in Bacterial Populations

Payne, P.; Geyrhofer, L.; Barton, N. H.; Bollback, J. P.

10.1101/181487 — evolutionary biology — Posted on 2017-08-28

203 Rational cell culture optimization enhances experimental reproducibility in cancer cells.

Wright Muelas, M.; Ortega, F.; Breitling, R.; Bendtsen, C.; Westerhoff, H. V.

10.1101/167148 — cell biology — Posted on 2017-08-28

204 Inter-homologue repair in fertilized human eggs?

Egli, D.; Zuccaro, M.; Kosicki, M.; Church, G.; Bradley, A.; Jasin, M.

10.1101/181255 — cell biology — Posted on 2017-08-28

205 ‘Switch-like’ transition from random to directed motility of microtubules by a yeast dynein

Jain, K.; Khetan, N.; Athale, C. A.

10.1101/181404 — biophysics — Posted on 2017-08-28

206 Optical Coherence Tomography Reveals Mechanobiologically Stable Self-Organizing Di-Fork Architecture of Mice Cutaneous Scars

Ghosh, B.; Mandal, M.; Mitra, P.; Chatterjee, J.

10.1101/181545 — biophysics — Posted on 2017-08-28

207 DrImpute: Imputing dropout events in single cell RNA sequencing data

Kwak, I.-Y.; Gong, W.; Koyano-Nakagawa, N.; Garry, D.

10.1101/181479 — bioinformatics — Posted on 2017-08-28

208 Analysis of deep learning methods for blind protein contact prediction in CASP12

Wang, S.; Sun, S.; Xu, J.

10.1101/181586 — bioinformatics — Posted on 2017-08-28

209 Folding membrane proteins by deep transfer learning

Wang, S.; Li, Z.; Yu, Y.; Xu, J.

10.1101/181628 — bioinformatics — Posted on 2017-08-28

210 Inhibition of Intracellular Lipolysis Promotes Cancer Cell Adaptation to Hypoxia

Zhang, X.; Saarinen, A. M.; Hitosugi, T.; Wang, Z.; Wang, L.; Ho, T. H.; Liu, J.

10.1101/181503 — biochemistry — Posted on 2017-08-28

211 Development of High-Throughput Screening Assays for Inhibitors of ETS Transcription Factors

Currie, S.; Warner, S. L.; Vankayalapati, H.; Liu, X.-H.; Sharma, S.; Bearss, D. J.; Graves, B. J.

10.1101/181420 — biochemistry — Posted on 2017-08-28

212 Whole-exome sequencing of plasma cell-free DNA portrays the somatic mutation landscape of refractory metastatic colorectal cancer and enables the discovery of mutated KDR/VEGFR2 receptors as modulators of anti-angiogenic therapies.

Toledo, R. A.; Garralda, E.; Mitsi, M.; Pons, T.; Monsech, J.; Vega, E.; Otero, A.; Albarran, M. I.; Banos, N.; Duran, Y.; Bonilla, V.; Sarno, F.; Camacho-Artacho, M.; Sanchez-Perez, T.; Perea, S.; Alvarez, R.; De Martino, A.; Lietha, D.; Blanco-Aparicio, C.; Cubillo, A.; Dominguez, O.; Martinez-Torrecuadrada, J. L.; Hidalgo, M.

10.1101/177287 — genomics — Posted on 2017-08-28

213 Medical relevance of protein-truncating variants across 337,208 individuals in the UK Biobank study

DeBoever, C.; Tanigawa, Y.; McInnes, G.; Lavertu, A.; Chang, C.; Bustamante, C. D.; Daly, M. J.; Rivas, M. A.

10.1101/179762 — genetics — Posted on 2017-08-28

214 Intra-voxel incoherent motion magnetic resonance imaging of the living human fetus: the technique and within-subject reproducibility

Jakab, A.; Tuura, R.; Kottke, R.; Kellenberger, C.; Scheer, I.

10.1101/180844 — bioinformatics — Posted on 2017-08-28

215 A Carbon Nanotube Optical Reporter Maps Endolysosomal Lipid Flux

Jena, P. V.; Roxbury, D.; Galassi, T. V.; Akkari, L.; Horoszko, C. P.; Iaea, D. B.; Budhathoki-Uprety, J.; Pipalia, N. H.; Haka, A. S.; Harvey, J. D.; Mittal, J.; Maxfield, F. R.; Joyce, J. A.; Heller, D. A.

10.1101/134999 — bioengineering — Posted on 2017-08-28

216 Temporal dynamics of gene expression in heat-stressed Caenorhabditis elegans

Jovic, K.; Sterken, M. G.; Grilli, J.; Bevers, R. P. J.; Rodriguez, M.; Riksen, J. A. G.; Allesina, S.; Kammenga, J. E.; Snoek, L. B.

10.1101/135988 — genomics — Posted on 2017-08-28

217 Parallel diversifications of Cremastosperma and Mosannona (Annonaceae), tropical rainforest trees tracking Neogene upheaval of the South American continent

Pirie, M. D.; Maas, P. J. M.; Wilschut, R.; Melchers-Sharrott, H.; Chatrou, L.

10.1101/141127 — evolutionary biology — Posted on 2017-08-28

218 Epidemic Potential for Human Infection with Influenza A (H7N9) Virus in China through Web Search Behaviors: A Data-Driven Study

Teng, Y.; Bi, D.; Guo, X.; Feng, D.; Tong, Y.

10.1101/168112 — epidemiology — Posted on 2017-08-27

219 Spindle asymmetry drives non-Mendelian chromosome segregation

Akera, T.; Chmatal, L.; Trimm, E.; Yang, K.; Aonbangkhen, C.; Chenoweth, D. M.; Janke, C.; Schultz, R. M.; Lampson, M. A.

10.1101/180869 — cell biology — Posted on 2017-08-27

220 Clonal heterogeneity influences the fate of new adaptive mutations

Vazquez-Garcia, I.; Salinas, F.; Li, J.; Fischer, A.; Barre, B.; Hallin, J.; Bergström, A.; Alonso-Perez, E.; Warringer, J.; Mustonen, V.; Liti, G.

10.1101/039859 — genetics — Posted on 2017-08-27

221 Slot-like capacity and resource-like coding in a neural model of multiple-item working memory

Standage, D.; Pare, M.

10.1101/181354 — neuroscience — Posted on 2017-08-27

222 Hierarchical recruitment of competition alleviates working memory overload in a fronto-parietal model

Standage, D.; Pare, M.; Blohm, G.

10.1101/181370 — neuroscience — Posted on 2017-08-27

223 Genomic and proteomic analysis of Human herpesvirus 6 reveals distinct clustering of acute versus inherited forms and reannotation of reference strain

Greninger, A.; Knudsen, G.; Roychoudhury, P.; Hanson, D.; Hall Sedlak, R. A.; Xie, H.; Guan, J.; Nguyen, T.; Peddu, V.; Boeckh, M.; Huang, M.-L.; Cook, L.; Depledge, D.; Zerr, D.; Koelle, D.; Gantt, S.; Yoshikawa, T.; Caserta, M.; Hill, J.; Jerome, K.

10.1101/181248 — microbiology — Posted on 2017-08-27

224 Ttc21b is required in Bergmann glia during postnatal cerebellar development

Driver, A. M.; Shumrick, C.; Stottmann, R.

10.1101/181230 — genetics — Posted on 2017-08-27

225 Patterns of structural variation in human cancer

Li, Y.; Roberts, N.; Weischenfeldt, J.; Wala, J. A.; Shapira, O.; Schumacher, S.; Khurana, E.; Korbel, J. O.; Imielinski, M.; Beroukhim, R.; Campbell, P.

10.1101/181339 — cancer biology — Posted on 2017-08-27

226 A "Tug of War" maintains a dynamic protein-membrane complex: MD simulations of C-Raf RBD-CRD bound to K-Ras4B at an anionic membrane

LI, Z.; Srivastava, P. P.; Buck, M.

10.1101/181347 — biophysics — Posted on 2017-08-27

227 A probabilistic model-based bi-clustering method for single-cell transcriptomic data analysis

Cao, S.; Sheng, T.; Chen, X.; Ma, Q.; Zhang, C.

10.1101/181362 — bioinformatics — Posted on 2017-08-27

228 Edge Detection of Cryptic Lamellipodia Assisted by Deep Learning

Wang, C.; Kang, S.; Kim, E.; Zhang, X.; Choi, H. J.; Choi, A.; Lee, K.

10.1101/181263 — bioinformatics — Posted on 2017-08-27

229 Prediction of early breast cancer patient survival using ensembles of hypoxia signatures

Gong, I. Y.; Fox, N. S.; Boutros, P.

10.1101/181289 — bioinformatics — Posted on 2017-08-27

230 Unearthing new genomic markers of drug response by improved measurement of discriminative power

Dang, C.; Peon, A.; Ballester, P.

10.1101/033092 — bioinformatics — Posted on 2017-08-27

231 Myeloablation-associated deletion of ORF4 in a human coronavirus 229E infection

Greninger, A.; Pepper, G.; Shean, R. C.; Cent, A.; Palileo, I.; Kuypers, J. M.; Schiffer, J. T.; Jerome, K. R.

10.1101/113423 — genomics — Posted on 2017-08-26

232 Opposite effects of lateralised transcranial alpha versus gamma stimulation on spatial attention

Wöstmann, M.; Vosskuhl, J.; Obleser, J.; Herrmann, C.

10.1101/180836 — neuroscience — Posted on 2017-08-26

233 Phylogenomics reveals an extensive history of genome duplication in diatoms (Bacillariophyta)

Parks, M.; Nakov, T.; Ruck, E. C.; Wickett, N. J.; Alverson, A. J.

10.1101/181115 — evolutionary biology — Posted on 2017-08-26

234 Epigenomic and 3D genome architecture in naïve and primed human embryonic stem cell states

Battle, S.; Doni Jayavelu, N.; Azad, R. N.; Hesson, J.; Ahmed, F. N.; Zoller, J. A.; Mathieu, J.; Ruohola-Baker, H.; Ware, C. B.; Hawkins, R.

10.1101/181123 — developmental biology — Posted on 2017-08-26

235 Type 2 diabetes promotes cell centrosome amplification and the role of AKT-ROS-dependent signalling of ROCK1 and 14-3-3σ

Wang, P.; Lu, Y. C.; Wang, J.; Wang, L.; Yu, H.; Li, Y. F.; Kong, A.; Chan, J.; Lee, S. C.

10.1101/181214 — cell biology — Posted on 2017-08-26

236 Behavioral and Hematological Response of Clarias gariepinus juvenile exposed to Acute concentrations of Aqueous Extract of Siam Weed (Chloromolaena odorata) leaf as Anesthetic agent

Iheanacho, S.; Nworu, S.

10.1101/181164 — zoology — Posted on 2017-08-26

237 NMDA receptor-dependent dynamics of hippocampal place cell ensembles

Hayashi, Y.

10.1101/181131 — neuroscience — Posted on 2017-08-26

238 The Anatomical Tracings of Lesions After Stroke (ATLAS) Dataset - Release 1.1

Liew, S.-L.; Anglin, J. M.; Banks, N. W.; Sondag, M.; Ito, K. L.; Kim, H.; Chan, J.; Ito, J.; Jung, C.; Lefebvre, S.; Nakamura, W.; Saldana, D.; Schmiesing, A.; Tran, C.; Vo, D.; Ard, T.; Heydari, P.; Kim, B.; Aziz-Zadeh, L.; Cramer, S. C.; Liu, J.; Soekadar, S.; Nordvik, J.-E.; Westlye, L. T.; Wang, J.; Winstein, C.; Yu, C.; Ai, L.; Koo, B.; Craddock, R. C.; Miham, M.; Lakich, M.; Pienta, A.; Stroud, A.

10.1101/179614 — neuroscience — Posted on 2017-08-26

239 Enhancer connectome in primary human cells reveals target genes of disease-associated DNA elements

10.1101/178269 — genomics — Posted on 2017-08-26

240 An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues

Corces, M. R.; Trevino, A. E.; Hamilton, E. G.; Greenside, P. G.; Sinnott-Armstrong, N. A.; Vesuna, S.; Satpathy, A. T.; Rubin, A. J.; Montine, K. S.; Wu, B.; Kathiria, A.; Cho, S. W.; Mumbach, M. R.; Carter, A. C.; Kasowski, M.; Orloff, L. A.; Risca, V. I.; Kundaje, A.; Khavari, P. A.; Montine, T. J.; Greenleaf, W. J.; Chang, H. Y.

10.1101/181206 — genomics — Posted on 2017-08-26

241 Dramatic evolution of body length due to post-embryonic changes in cell size in a newly discovered close relative of C. elegans

Woodruff, G. C.; Phillips, P. C.; Kanzaki, N.

10.1101/181107 — evolutionary biology — Posted on 2017-08-26

242 Not such silly sausages: Northern quolls exhibit aversion to toads after training with toad sausages.

Indigo, N. L.; Smith, J.; Webb, J.; Phillips, B.

10.1101/181149 — ecology — Posted on 2017-08-26

243 BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone

Ye, F.; Nager, A. R.; Nachury, M. V.

10.1101/180620 — cell biology — Posted on 2017-08-26

244 Seamless Multiscale Modeling of Coagulation Using Dissipative Particle Dynamics

Yazdani, A.; Li, Z.; Humphrey, J.; Karniadakis, G.

10.1101/181099 — biophysics — Posted on 2017-08-26

245 Multi-reference spectral library yields almost complete coverage of heterogeneous LC-MS/MS data sets

Ammar, C.; Berchtold, E.; Csaba, G.; Schmidt, A.; Imhof, A.; Zimmer, R.

10.1101/180448 — bioinformatics — Posted on 2017-08-26

246 GSimp: A Gibbs sampler based left-censored missing value imputation approach for metabolomics studies

Wei, R.; Wang, J.; Jia, E.; Chen, T.; Ni, Y.; Jia, W.

10.1101/177410 — bioinformatics — Posted on 2017-08-26

247 B-cell receptor reconstruction from single-cell RNA-seq with VDJPuzzle

Rizzetto, S.; Koppstein, D. N.; Samir, J.; Singh, M.; Reed, J. H.; Cai, C. H.; Lloyd, A. R.; Eltahla, A. A.; Goodnow, C. C.; Luciani, F.

10.1101/181156 — bioinformatics — Posted on 2017-08-26

248 Single-cell RNA-seq reveals intrinsic and extrinsic regulatory heterogeneity in yeast responding to stress

Gasch, A. P.; Yu, F. B.; Hose, J.; Escalante, L. E.; Place, M.; Bacher, R.; Kanbar, J.; Ciobanu, D.; Sandor, L.; Grigoriev, I. V.; Kendziorski, C.; Quake, S. R.; McClean, M. N.

10.1101/179093 — systems biology — Posted on 2017-08-26

249 Convergence of dispersed regulatory mutations predicts driver genes in prostate cancer

Sallari, R. C.; Sinnott-Armstrong, N. A.; French, J. D.; Kron, K. J.; Ho, J.; Moore, J. H.; Stambolic, V.; Edwards, S. L.; Lupien, M.; Kellis, M.

10.1101/097451 — genomics — Posted on 2017-08-26

250 Replicating and cycling stores of information perpetuate life

Jose, A. M.

10.1101/149294 — developmental biology — Posted on 2017-08-26

251 Identifying the genetic determinants of particular phenotypes in microbial genomes with very small training sets

Long, G. S.; Hussen, M.; Dench, J.; Aris-Brosou, S.

10.1101/181222 — bioinformatics — Posted on 2017-08-26

252 Copb2 Is Essential For Embryogenesis And Hypomorphic Mutations Cause Human Microcephaly

DiStasio, A.; Driver, A.; Sund, K.; Donlin, M.; Muraleedharan, R. M.; Pooya, S.; Kline-Fath, B.; Kaufman, K.; Prows, C.; Schorry, E.; DasGupta, B.; Stottmann, R.

10.1101/135236 — genetics — Posted on 2017-08-26

253 Separable functions of the PHD finger protein Spp1 in the Set1 and the meiotic DSB forming complexes cooperate for meiotic DSB formation.

Adam, C.; Guerois, R.; Citarella, A.; Verardi, L.; Adolphe, F.; Beneut, C.; Sommermeyer, V.; Ramus, C.; Govin, J.; Coute, Y.; Borde, V.

10.1101/181180 — molecular biology — Posted on 2017-08-26

254 Plant genes influence microbial hubs that shape beneficial leaf communities

10.1101/181198 — microbiology — Posted on 2017-08-26

255 Sensitivity analysis based ranking reveals unknown biological hypotheses for down regulated genes in time buffer during administration of PORCN-WNT inhibitor ETC-1922159 in CRC

Sinha, S.

10.1101/180927 — cancer biology — Posted on 2017-08-26

256 Systemic post-translational control of bacterial metabolism regulates adaptation in dynamic environments

Brunk, E.; Chang, R. L.; Xia, J.; Hefzi, H.; Yurkovich, J. T.; Kim, D.; Buckmiller, E.; Wang, H.; Yang, C.; Palsson, B. O.; Church, G.; Lewis, N. E.

10.1101/180646 — systems biology — Posted on 2017-08-25

257 Contributions of different prefrontal cortical regions to abstract rule acquisition and reversal in monkeys

La Camera, G.; Bouret, S.; Richmond, B. J.

10.1101/180893 — neuroscience — Posted on 2017-08-25

258 Optogenetic inhibition reveals distinct roles for basolateral amygdala activity at discrete timepoints during risky decision making

Orsini, C. A.; Hernandez, C. M.; Singhal, S.; Kelly, K. B.; Frazier, C. J.; Bizon, J. L.; Setlow, B.

10.1101/180885 — neuroscience — Posted on 2017-08-25

259 Living Neural Networks: Dynamic Network Analysis of Developing Neural Progenitor Cells

Mahadevan, A. S.; Grandel, N. E.; Robinson, J. T.; Qutub, A. A.

10.1101/055533 — neuroscience — Posted on 2017-08-25

260 Gaze-stabilizing central vestibular neurons project asymmetrically to extraocular motoneuron pools

Schoppik, D.; Bianco, I. H.; Prober, D. A.; Douglass, A. D.; Robson, D. N.; Li, J. M. B.; Greenwood, J. S. F.; Soucy, E.; Engert, F.; Schier, A. F.

10.1101/151548 — neuroscience — Posted on 2017-08-25

261 Glycan Clock Forecasts Human Influenza A Virus Hemagglutinin Evolution

Altman, M. O.; Angel, M.; Kosik, I.; Gibbs, J. S.; Trovao, N. S.; Zost, S. J.; Hensley, S. E.; Nelson, M. I.; Yewdell, J. W.

10.1101/163345 — microbiology — Posted on 2017-08-25

262 The molecular mechanism of N-acetylglucosamine side-chain attachment to the Lancefield group A Carbohydrate in Streptococcus pyogenes

Rush, J. S.; Edgar, R. J.; Deng, P.; Chen, J.; Zhu, H.; van Sorge, N. M.; Morris, A. J.; Korotkov, K. V.; Korotkova, N.

10.1101/180810 — microbiology — Posted on 2017-08-25

263 Enhancement of non-specific immune responses in European sea bass (Dicentrarchus labrax, L. 1758) by geophyte extract injections (Urginea maritima and Muscari comosum)

Ulukoy, G.; Baba, E.; Mammadov, R.

10.1101/180851 — immunology — Posted on 2017-08-25

264 Inhibition of p53 improves CRISPR/Cas-mediated precision genome editing

Haapaniemi, E.; Botla, S. K.; Persson, J.; Schmierer, B.; Taipale, J.

10.1101/180943 — genomics — Posted on 2017-08-25

265 pdxBlacklist: Identifying artefactual variants in patient-derived xenograft samples

Salm, M.; Schelhorn, S.-E.; Lancashire, L.; Grombacher, T.

10.1101/180752 — genomics — Posted on 2017-08-25

266 Insights into regeneration from the genome, transcriptome and metagenome analysis of Eisenia fetida

Bhambri, A.; Dhaunta, N.; Patel, S. S.; Hardikar, M.; Srikakulam, N.; Shridhar, S.; Vellarikkal, S.; Suryawanshi, H.; Pandey, R.; Jayarajan, R.; Verma, A.; Kumar, V.; Bhatt, A.; Gautam, P.; Rai, M.; Khan, J. A.; Fromm, B.; Peterson, K. J.; Scaria, V.; Sivasubbu, S.; Pillai, B.

10.1101/180612 — genomics — Posted on 2017-08-25

267 Estimation Of Genomic Prediction Accuracy From Reference Populations With Varying Degrees Of Relationship

Lee, S. H.; Clark, S.; van der Werf, J.

10.1101/119164 — genetics — Posted on 2017-08-25

268 Cryptic variation in quantitative spatial gene expression in Drosophila

Ali, S.; Signor, S.; Kozlov, K.; Nuzhdin, S.

10.1101/175711 — developmental biology — Posted on 2017-08-25

269 Competition between microtubule-associated proteins directs motor transport

Monroy, B. Y.; Sawyer, D. L.; Ackermann, B. E.; Borden, M. M.; Tan, T. C.; Ori-McKenney, K. M.

10.1101/180935 — cell biology — Posted on 2017-08-25

270 Intra-voxel incoherent motion magnetic resonance imaging of the living human fetus: the technique and within-subject reproducibility

Jakab, A.; Tuura, R.; Kottke, R.; Kellenberger, C.; Scheer, I.

10.1101/180844 — bioinformatics — Posted on 2017-08-25

271 Genome shuffling in a globalized bacterial plant pathogen: Recombination-mediated evolution in Xanthomonas euvesicatoria and X. perforans

Jibrin, M. O.; Potnis, N.; Timilsina, S.; Minsavage, G. V.; Vallad, G. E.; Roberts, P. D.; Jones, J. B.; Goss, E. M.

10.1101/180901 — evolutionary biology — Posted on 2017-08-25

272 Spindle asymmetry drives non-Mendelian chromosome segregation

Akera, T.; Trimm, E.; Chmatal, L.; Yang, K.; Aonbangkhen, C.; Chenoweth, D. M.; Janke, C.; Schultz, R. M.; Lampson, M. A.

10.1101/180869 — cell biology — Posted on 2017-08-25

273 MicroRNAs from the parasitic plant Cuscuta campestris target host messenger RNAs

Shahid, S.; Kim, G.; Johnson, N. R.; Wafula, E.; Wang, F.; Coruh, C.; Bernal-Galeano, V.; dePamphilis, C. W.; Westwood, J. H.; Axtell, M.

10.1101/180497 — plant biology — Posted on 2017-08-25

274 Nuclear transcriptomes at high resolution using retooled INTACT

Reynoso, M. A.; Pauluzzi, G. C.; Kajala, K.; Cabanlit, S.; Velasco, J.; Bazin, J.; Deal, R.; Sinha, N. R.; Brady, S. M.; Bailey-Serres, J.

10.1101/180992 — plant biology — Posted on 2017-08-25

275 The lawful imprecision of human surface tilt estimation in natural scenes

Kim, S.; Burge, J.

10.1101/180984 — neuroscience — Posted on 2017-08-25

276 Predictive feedback to V1 dynamically updates with sensory input

Edwards, G.; Vetter, P.; McGruer, F.; Petro, L. S.; Muckli, L.

10.1101/180539 — neuroscience — Posted on 2017-08-25

277 Super-Resolution Microscopy Reveals Structural Mechanisms Driving the Nanoarchitecture of a Viral Chromatin Tether

Grant, M. J.; Kedes, D. H.; Smith, M. M.

10.1101/181016 — microbiology — Posted on 2017-08-25

278 On somatic constraints in the evolution of multicellularity

Rozhok, A.; DeGregori, J.

10.1101/181065 — evolutionary biology — Posted on 2017-08-25

279 The geometry of partial fitness orders and an efficient method for detecting genetic interactions

Lienkaemper, C.; Lamberti, L.; Drain, J.; Beerenwinkel, N.; Gavryushkin, A.

10.1101/180976 — evolutionary biology — Posted on 2017-08-25

280 Induction of differentiation and metabolic reprogramming in human hepatoma cells by adult human serum

Steenbergen, R. H.; Oti, M.; ter Horst, R.; Tat, W.; Neufeldt, C.; Belovodskiy, A.; Chua, T. T.; Cho, W. J.; Joyce, M.; Dutilh, B. E.; Tyrrell, D. L.

10.1101/180968 — cell biology — Posted on 2017-08-25

281 Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors

Henssen, A.; Reed, C.; Jiang, E.; Garcia, H. D.; von Stebut, J.; MacArthur, I.; Hundsdoerfer, P.; Hyun Kim, J.; de Stanchina, E.; Kuwahara, Y.; Hosoi, H.; Ganem, N.; Dela Cruz, F.; Kung, A.; Schulte, J.; Petrini, J.; Kentsis, A.

10.1101/181040 — cancer biology — Posted on 2017-08-25

282 Low Perfusion Compartments in Glioblastoma Quantified by Advanced Magnetic Resonance Imaging: Correlation with Patient Survival

Li, C.; Yan, J.-L.; Torheim, T.; McLean, M. A.; Boonzaier, N. R.; Huang, Y.; Van Dijken, B. R. J.; Matys, T.; Markowetz, F.; Price, S. J.

10.1101/180521 — cancer biology — Posted on 2017-08-25

283 Preparation of H-Ras GTPase conjugated to lipid nanodiscs for NMR spectroscopy

Kovrigina, E.; Shah, S.; Kovrigin, E.

10.1101/181032 — biophysics — Posted on 2017-08-25

284 Evidence for evolutionary shifts in the fitness landscape of human complex traits

Uricchio, L. H.; Kitano, H. C.; Gusev, A.; Zaitlen, N. A.

10.1101/173815 — evolutionary biology — Posted on 2017-08-25

285 Chunking as a rational strategy for lossy data compression in visual working memory

Nassar, M. R.; Helmers, J. C.; Frank, M. J.

10.1101/098939 — neuroscience — Posted on 2017-08-25

286 A Longitudinal Model for Functional Connectivity Using Resting-State fMRI

Hart, B.; Cribben, I.; Fiecas, M.

10.1101/152538 — neuroscience — Posted on 2017-08-25

287 Bayesian Efficient Coding

Park, I. M.; Pillow, J. W.

10.1101/178418 — neuroscience — Posted on 2017-08-25

288 Activated CD8 T cells express two distinct P-Selectin Ligands

Carlow, D. A.; Tra, M. C.; Ziltener, H. J.

10.1101/167957 — immunology — Posted on 2017-08-25

289 The genetic basis of human brain structure and function: 1,262 genome-wide associations found from 3,144 GWAS of multimodal brain imaging phenotypes from 9,707 UK Biobank participants

Elliott, L.; Sharp, K.; Alfaro-Almagro, F.; Douaud, G.; Miller, K.; Marchini, J.; Smith, S.

10.1101/178806 — genetics — Posted on 2017-08-25

290 Prevalence of Mycoplasma genitalium in different population groups: systematic review and meta-analysis

Baumann, L.; Cina, M.; Egli-Gany, D.; Goutaki, M.; Halbeisen, F.; Lohrer, G.-R.; Ali, H.; Scott, P.; Low, N.

10.1101/180422 — epidemiology — Posted on 2017-08-25

291 Structural basis for terminal loop recognition and processing of pri-miRNA-18a by hnRNP A1

Kooshapur, H.; Choudhury, N. R.; Simon, B.; Muehlbauer, M.; Jussupow, A.; Fernandez, N.; Dallmann, A.; Gabel, F.; Camilloni, C.; Michlewski, G.; Caceres, J. F.; Sattler, M.

10.1101/178855 — molecular biology — Posted on 2017-08-25

292 Transient telomerase inhibition alters cell cycle kinetics

Thompson, C. A. H.; Gu, A. Y. M.; Yang, S. Y.; Mathew, V.; Fleisig, H.; Wong, J. M. Y.

10.1101/158287 — cancer biology — Posted on 2017-08-25

293 Leaf-GP: An Open and Automated Software Application for Measuring Growth Phenotypes for Arabidopsis and Wheat

Zhou, J.; Applegate, C.; Dobon Alonso, A.; Reynolds, D.; Orford, S.; Mackiewicz, M.; Griffiths, S.; Penfield, S.; Pullen, N.

10.1101/180083 — plant biology — Posted on 2017-08-25

294 Decline of auditory-motor speech processing in older adults with hearing loss

Panouilleres, M.; Mottonen, R.

10.1101/169235 — neuroscience — Posted on 2017-08-25

295 Unique genomic features and deeply-conserved functions of long non-coding RNAs in the Cancer LncRNA Census (CLC)

Carlevaro-Fita, J.; Lanzos, A.; Feuerbach, L.; Hong, C.; Mas-Ponte, D.; PCAWG Driver Identification Working Group 2-5-9-14, ; Guigo, R.; Pedersen, J. S.; Johnson, R.

10.1101/152769 — genomics — Posted on 2017-08-25

296 Identification of Genetically Important Individuals of the Rediscovered Floreana Galapagos Giant Tortoise (Chelonoidis elephantopus) Provide Founders for Species Restoration Program

Miller, J.; Quinzin, M. C.; Poulakakis, N.; Gibbs, J. P.; Beheregaray, L. B.; Garrick, R. C.; Russello, M. A.; Ciofi, C.; Edwards, D. L.; Hunter, E. A.; Tapia, W.; Rueda, D.; Carrion, J.; Valdivieso, A. A.; Caccone, A.

10.1101/143131 — evolutionary biology — Posted on 2017-08-25

297 Gene markers for exon capture and phylogenomics in ray-finned fishes

Jiang, J.; Yuan, H.; Zheng, X.; Wang, Q.; Kuang, T.; Li, J.; Liu, J.; Song, S.; Wang, W.; Cheng, F.; Li, H.; Huang, J.; Li, C.

10.1101/180786 — evolutionary biology — Posted on 2017-08-25

298 Somatic developmental defects in dmrad51/spnA mutant show low temperature sensitivity with enhanced genomic damages and cell death

Khan, C.; Muliyil, S.; Ayyub, C.; Rao, B. J.

10.1101/180737 — developmental biology — Posted on 2017-08-25

299 The PtdIns3P-binding protein Phafin2 escorts macropinosomes through the cortical actin cytoskeleton

Schink, K. O.; Tan, K. W.; Spangenberg, H.; Martorana, D.; Sneeggen, M.; Campsteijn, C.; Raiborg, C.; Stenmark, H.

10.1101/180760 — cell biology — Posted on 2017-08-25

300 Modeling the Mechanism of CLN025Beta-Hairpin Formation

McKiernan, K. A.; Husic, B. E.; Pande, V. S.

10.1101/145185 — biophysics — Posted on 2017-08-25

301 Motor reattachment kinetics play a dominant role in multimotor-driven cargo transport

Feng, Q.; Mickolajczyk, K. J.; Chen, G.-Y.; Hancock, W. O.

10.1101/180778 — biophysics — Posted on 2017-08-25

302 Persistent one-way walking in a circular arena in Drosophila melanogaster Canton-S strain

Xiao, C.; Qiu, S.; Robertson, R. M.

10.1101/145888 — animal behavior and cognition — Posted on 2017-08-25

303 Effective connectivity inferred from fMRI transition dynamics during movie viewing points to a balanced reconfiguration of cortical interactions

Gilson, M.; Deco, G.; Friston, K.; Hagmann, P.; Mantini, D.; Betti, V.; Romani, G. L.; Corbetta, M.

10.1101/110015 — neuroscience — Posted on 2017-08-25

304 Organizational Hierarchy and Structural Diversity of Microvascular Pericytes in Adult Mouse Cortex

Grant, R. I.; Hartmann, D. A.; Underly, R. G.; Berthiaume, A.-A.; Bhat, N. R.; Shih, A. Y.

10.1101/114777 — neuroscience — Posted on 2017-08-25

305 A Comprehensive Assessment of Reproducibility of R-fMRI Metrics on the Impact of Different Strategies for Multiple Comparison Correction and Sample Sizes

Chen, X.; Lu, B.; Yan, C.-G.

10.1101/128645 — neuroscience — Posted on 2017-08-25

306 Rapid whole brain imaging of neural activity in freely behaving larval zebrafish (Danio rerio)

Cong, L.; Wang, Z.; Chai, Y.; Hang, W.; Shang, C.; Yang, W.; Bai, L.; Du, J.; Wang, K.; Wen, Q.

10.1101/131532 — neuroscience — Posted on 2017-08-25

307 HIV alters CD4/CXCR4 expression patterns in OP9-DL1-mediated differentiation of human cord-derived CD34+ cells

Tsukamoto, T.

10.1101/142539 — microbiology — Posted on 2017-08-25

308 Normalization of the microbiota in patients after treatment for colonic lesions

Sze, M. A.; Baxter, N. T.; Ruffin, M. T.; Rogers, M. A.; Schloss, P. D.

10.1101/138222 — microbiology — Posted on 2017-08-25

309 Chromosome contacts in activated T cells identify autoimmune disease candidate genes

Burren, O. S.; Rubio Garcia, A.; Javierre, B.-M.; Rainbow, D. B.; Cairns, J.; Cooper, N. J.; Lambourne, J. J.; Schofield, E.; Dopico, X. C.; Ferreira, R. C.; Coulson, R.; Burden, F.; Rowlston, S. P.; Downes, K.; Wingett, S. W.; Frontini, M.; Ouwehand, W. H.; Fraser, P.; Spivakov, M.; Todd, J. A.; Wicker, L. S.; Cutler, A. J.; Wallace, C.

10.1101/100958 — genomics — Posted on 2017-08-25

310 Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders

Nguyen, H. T.; Bryois, J.; Kim, A.; Dobbyn, A.; Huckins, L. M.; Munoz-Manchado, A.; Ruderfer, D.; Genovese, G.; Fromer, M.; Xu, X.; Pinto, D.; Linnarsson, S.; Verhage, M.; Smit, G.; Hjerling-Leffler, J.; Buxbaum, J.; Hultman, C.; Sklar, P.; Purcell, S. M.; Lage, K.; He, X.; Sullivan, P. F.; Stahl, E. A.

10.1101/135293 — genomics — Posted on 2017-08-25

311 Changes in free amino acid concentrations and associated gene expression profiles in the abdominal muscle of kuruma shrimp Marsupenaeus japonicus reared at different salinity

Koyama, H.; Mizusawa, N.; Hoashi, M.; Tan, E.; Yasumoto, K.; Jimbo, M.; Ikeda, D.; Yokoyama, T.; Asakawa, S.; Piyapattanakorn, S.; Watabe, S.

10.1101/180638 — zoology — Posted on 2017-08-25

312 The impact of dew-induced transpiration suppression on the water and isotope balances of Colocasia esculenta leaves

Gerlein-Safdi, C.; Gauthier, P. P. G.; Caylor, K. K.

10.1101/178293 — plant biology — Posted on 2017-08-25

313 Synthesis, secretion, and perception of abscisic acid regulates stress responses in Chlorella sorokiniana

Khasin, M.; Cahoon, R. E.; Alvarez, S.; Beckeris, R. G.; Eyun, S.-i.; Jia, Q.; Riethoven, J.-J.; Nickerson, K. W.; Riekhof, W. R.

10.1101/180547 — plant biology — Posted on 2017-08-25

314 Stable representation of sounds in the posterior striatum during flexible auditory decisions

Guo, L.; Walker, W. I.; Ponvert, N. D.; Penix, P. L.; Jaramillo, S.

10.1101/180505 — neuroscience — Posted on 2017-08-25

315 Macrophage-to-sensory neuron crosstalk mediated by Angiotensin II type-2 receptor elicits neuropathic pain

10.1101/166546 — neuroscience — Posted on 2017-08-25

316 Quasi-Periodic Patterns of Intrinsic Brain Activity in Individuals and their Relationship to Global Signal

Yousefi, B.; Shin, J.; Schumacher, E. H.; Keilholz, S. D.

10.1101/180596 — neuroscience — Posted on 2017-08-25

317 A neural algorithm for a fundamental computing problem

Dasgupta, S.; Stevens, C. F.; Navlakha, S.

10.1101/180471 — neuroscience — Posted on 2017-08-25

318 The psychological arrow of time and the human brain dynamics of event ordering

Gauthier, B.; Pestke, K.; van Wassenhove, V.

10.1101/180711 — neuroscience — Posted on 2017-08-25

319 Ventral hippocampal CA1 and CA3 differentially mediate learned approach-avoidance conflict processing

Schumacher, A.; Villaruel, F.; Riaz, S.; Lee, A. C. H.; Ito, R.

10.1101/180513 — neuroscience — Posted on 2017-08-25

320 The influence of startReact on long-latency reflexive muscle activation during the transition from posture to movement

Honeycutt, C. F.; Ravichandran, V. J.; Perreault, E. J.

10.1101/180554 — neuroscience — Posted on 2017-08-25

321 The 10,000 Immunomes Project: A resource for human immunology

Zalocusky, K. A.; Kan, M. J.; Hu, Z.; Dunn, P.; Thomson, E.; Wiser, J.; Bhattacharya, S.; Butte, A. J.

10.1101/180489 — immunology — Posted on 2017-08-25

322 De novo assembly and phasing of dikaryotic genomes from two isolates of Puccinia coronata f. sp. avenae, the causal agent of oat crown rust

Miller, M. E.; Zhang, Y.; Omidvar, V.; Sperschneider, J.; Schwessinger, B.; Raley, C.; Palmer, J. M.; Garnica, D.; Upadhyaya, N.; Rathjen, J.; Taylor, J. M.; Park, R. F.; Dodds, P. N.; Hirsch, C. D.; Kianian, S. F.; Figueroa, M.

10.1101/179226 — genomics — Posted on 2017-08-25

323 A practical solution for preserving single cells for RNA sequencing

Attar, M.; Sharma, E.; Li, S.; Bryer, C.; Cubitt, L.; Broxholme, J.; Lockstone, H.; Kinchen, J.; Simmons, A.; Piazza, P.; Buck, D.; Livak, K. J.; Bowden, R.

10.1101/160804 — genomics — Posted on 2017-08-25

324 No evidence for association with APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populations

Kimuda, M. P.; Noyes, H.; Mulindwa, J.; Enyaru, J.; Alibu, V. P.; Sidibe, I.; Mumba, D.; Hertz-Fowler, C.; MacLeod, A.; Tastan Bishop, O.; Matovu, E.; TrypanoGEN Res. Grp., as members of The H3Africa C,

10.1101/180679 — genetics — Posted on 2017-08-25

325 Somatic developmental defects in dmrad51/spnA mutant show low temperature sensitivity with enhanced genomic damages and cell death

Khan, C.; Muliyil, S.; Ayyub, C.; Rao, B. J.

10.1101/180737 — developmental biology — Posted on 2017-08-25

326 A transgenic zebrafish model for the in vivo study of the blood and choroid plexus brain barriers using claudin 5

van Leeuwen, L.; Evans, R.; Jim, K. K.; Verboom, T.; Fang, X.; Bojarczuk, A.; Malicki, J.; Johnston, S.; van der Sar, A.

10.1101/180653 — developmental biology — Posted on 2017-08-25

327 Primary cilia mediate diverse kinase inhibitor resistance mechanisms in cancer

Jenks, A. D.; Vyse, S.; Wong, J. P.; Keller, D.; Burgoyne, T.; Shoemark, A.; de la Roche, M.; Tsalikis, A.; Michaelis, M.; Cinatl, J.; Huang, P. H.; Tanos, B. E.

10.1101/180257 — cell biology — Posted on 2017-08-25

328 The PtdIns3P-binding protein Phafin2 escorts macropinosomes through the cortical actin cytoskeleton

Schink, K. O.; Tan, K. W.; Spangenberg, H.; Martorana, D.; Sneeggen, M.; Campsteijn, C.; Raiborg, C.; Stenmark, H.

10.1101/180760 — cell biology — Posted on 2017-08-25

329 GPU-accelerated alignment of bisulfite-treated short-read sequences

Wilton, R.; Li, X.; Feinberg, A. P.; Szalay, A. S.

10.1101/175729 — bioinformatics — Posted on 2017-08-25

330 An ensemble learning approach to auto-annotation for whole-brain C. elegans imaging

Wu, S.; Toyoshima, Y.; Jang, M. S.; Kanamori, M.; Teramoto, T.; Iwasaki, Y.; Ishihara, T.; Iino, Y.; Yoshida, R.

10.1101/180430 — bioinformatics — Posted on 2017-08-25

331 Notos - a Galaxy tool to analyze CpN observed expected ratios for inferring DNA methylation types

Bulla, I.; Aliaga, B.; Lacal, V.; Bulla, J.; Grunau, C.; Chaparro, C.

10.1101/180463 — bioinformatics — Posted on 2017-08-25

332 Determining the optimal number of independent components for reproducible transcriptomic data analysis

Kairov, U.; Cantini, L.; Greco, A.; Molkenov, A.; Czerwinska, U.; Barillot, E.; Zinovyev, A.

10.1101/180687 — bioinformatics — Posted on 2017-08-25

333 Asymmetric MukB ATPases are regulated independently by the N- and C-terminal domains of MukF kleisin

Zawadzka, K.; Zawadzki, P.; Baker, R.; Rajasekar, K.; Sherratt, D. J.; Arciszewska, L.

10.1101/180729 — biochemistry — Posted on 2017-08-25

334 Chick cranial neural crest cells migrate by progressively refining the polarity of their protrusions.

Genuth, M. A.; Allen, C. D.; Mikawa, T.; Weiner, O.

10.1101/180299 — developmental biology — Posted on 2017-08-24

335 The BMP2/4 ortholog Dpp functions as an inter-organ signal that regulates developmental timing in Drosophila

Setiawan, L.; Woods, A. L.; Hariharan, I. K.

10.1101/180562 — developmental biology — Posted on 2017-08-24

336 cytoNet: Network Analysis of Cell Communities

Mahadevan, A. S.; Long, B. L.; Hu, C. W.; Ryan, D. T.; Britton, G. L.; Ligeralde, A.; Warmflash, A.; Robinson, J. T.; Qutub, A. A.

10.1101/180273 — bioengineering — Posted on 2017-08-24

337 DNA sequence encodes the position of DNA supercoils

Kim, S. H.; Ganji, M.; Torre, J. v. d.; Abbondanzieri, E.; Dekker, C.

10.1101/180414 — biophysics — Posted on 2017-08-24

338 A Data Citation Roadmap for Scientific Publishers

Cousijn, H.; Kenall, A.; Ganley, E.; Harrison, M.; Kernohan, D.; Lemberger, T.; Murphy, F.; Polischuk, P.; Taylor, S.; Martone, M.; Clark, T.

10.1101/100784 — scientific communication and education — Posted on 2017-08-24

339 Post-transcriptional remodelling is temporally deregulated during motor neurogenesis in human ALS models

Luisier, R.; Tyzack, G. E.; Hall, C. E.; Ule, J.; Luscombe, N. M.; Patani, R.

10.1101/180372 — neuroscience — Posted on 2017-08-24

340 Propagation of Beta/Gamma Rhythms in the Cortico-Basal Ganglia Circuits of the Parkinsonian Rat

West, T. O.; Berthouze, L.; Farmer, S. F.; Halliday, D.; Litvak, V.; Magill, P. J.; Sharott, A.

10.1101/180455 — neuroscience — Posted on 2017-08-24

341 Category learning biases sensory representations in human visual cortex.

Ester, E. F.; Sprague, T. C.; Serences, J. T.

10.1101/170845 — neuroscience — Posted on 2017-08-24

342 Efficient in situ barcode sequencing using padlock probe-based BaristaSeq

Chen, X.; Sun, Y.-C.; Church, G. M.; Lee, J. H.; Zador, A. M.

10.1101/180323 — molecular biology — Posted on 2017-08-24

343 Differential gene expression in chicken primary B cells infected ex vivo with attenuated and very virulent strains of infectious bursal disease virus (IBDV)

Dulwich, K. L.; Giotis, E. S.; Gray, A.; Nair, V.; Skinner, M. A.; Broadbent, A. J.

10.1101/180158 — microbiology — Posted on 2017-08-24

344 Universal correction of enzymatic sequence bias reveals molecular signatures of protein/DNA interactions

Martins, A. L.; Walavalkar, N. M.; Anderson, W. D.; Zang, C.; Guertin, M. J.

10.1101/104364 — genomics — Posted on 2017-08-24

345 Using Connectivity To Identify Climatic Drivers Of Local Adaptation

Macdonald, S. L.; Llewelyn, J.; Phillips, B.

10.1101/145169 — evolutionary biology — Posted on 2017-08-24

346 Novel Magnetic Resonance Imaging strategy targeting Neurotensin Receptors in detection of Prostate Cancer

Desai, M. M.; Tam, N.; Carraway, R.; Ho, S.-M.; Ferris, C.; King, J.

10.1101/180042 — cancer biology — Posted on 2017-08-24

347 eIF4A is stimulated by the pre-initiation complex and enhances recruitment of mRNAs regardless of structural complexity

Yourik, P.; Aitken, C. E.; Zhou, F.; Gupta, N.; Hinnebusch, A. G.; Lorsch, J. R.

10.1101/147959 — biophysics — Posted on 2017-08-24

348 Binding Thermodynamics and Kinetics Calculations Using Chemical Host and Guest: A Comprehensive Picture of Molecular Recognition

Tang, Z.; Chang, C.-e.

10.1101/155275 — biophysics — Posted on 2017-08-24

349 Chiron: Translating nanopore raw signal directly into nucleotide sequence using deep learning

Teng, H.; Hall, M. B.; Duarte, T.; Cao, M. D.; Coin, L.

10.1101/179531 — bioinformatics — Posted on 2017-08-24

350 SOMSC: Self-Organization-Map for High-Dimensional Single-Cell Data of Cellular States and Their Transitions

Peng, T.; Nie, Q.

10.1101/124693 — bioinformatics — Posted on 2017-08-24

351 Towards selective-alignment: Bridging the accuracy gap between alignment-based and alignment-free transcript quantification

Sarkar, H.; Zakeri, M.; Malik, L.; Patro, R.

10.1101/138800 — bioinformatics — Posted on 2017-08-24

352 Structural analyses reveal that the ATG2A-WIPI4 complex functions as a membrane tether for autophagosome biogenesis

Chowdhury, S.; Otomo, C.; Leitner, A.; Ohashi, K.; Aebersold, R.; Lander, G. C.; Otomo, T.

10.1101/180315 — biochemistry — Posted on 2017-08-24

353 P-values and confidence intervals: not fit for purpose?

Pharoah, P.; Jones, M. R.; Kar, S.

10.1101/180117 — scientific communication and education — Posted on 2017-08-24

354 A plant receptor-like kinase promotes cell-to-cell spread of RNAi and is targeted by a virus

Rosas-Diaz, T.; Zhang, D.; Fan, P.; Wang, L.; Ding, X.; Jiang, Y.; Jimenez-Gongora, T.; Medina-Puche, L.; Zhao, X.; Feng, Z.; Zhang, G.; Liu, X.; Bejarano, E. R.; Tan, L.; Zhu, J.-K.; Xing, W.; Faulkner, C.; Nagawa, S.; Lozano-Duran, R.

10.1101/180380 — plant biology — Posted on 2017-08-24

355 Differential spatiotemporal representations along the hippocampal long axis in humans

Brunec, I. K.; Bellana, B.; Ozubko, J. D.; Man, V.; Robin, J.; Liu, Z.-X.; Grady, C.; Rosenbaum, R. S.; Winocur, G.; Barense, M. D.; Moscovitch, M.

10.1101/179655 — neuroscience — Posted on 2017-08-24

356 Computer Simulations Predict High Structural Heterogeneity of Functional State of NMDA Receptors

Sinitskiy, A. V.; Pande, V. S.

10.1101/180091 — neuroscience — Posted on 2017-08-24

357 Alpha activity in the ventral and dorsal visual stream controls information flow during working memory

Leszczynski, M.; Fell, J.; Jensen, O.; Axmacher, N.

10.1101/180166 — neuroscience — Posted on 2017-08-24

358 What if you are not certain? A common computation underlying action selection, reaction time and confidence judgment

Christopoulos, V.; Enachescu, V.; Schrater, P.; Schaal, S.

10.1101/180281 — neuroscience — Posted on 2017-08-24

359 Signal complexity of human intracranial EEG tracks successful associative memory formation across individuals

Sheehan, T. C.; Sreekumar, V.; Inati, S. K.; Zaghloul, K. A.

10.1101/180240 — neuroscience — Posted on 2017-08-24

360 A unifying motif for spatial and directional surround suppression

Liu, L. D.; Miller, K. D.; Pack, C. C.

10.1101/180125 — neuroscience — Posted on 2017-08-24

361 The Neural Basis of Motivational Influences on Cognitive Control: An ALE Meta-Analysis

Parro, C.; Dixon, M. L.; Christoff, K.

10.1101/113126 — neuroscience — Posted on 2017-08-24

362 Post-transcriptional remodelling is temporally deregulated during motor neurogenesis in human ALS models

Luisier, R.; Tyzack, G. E.; Hall, C. E.; Ule, J.; Luscombe, N. M.; Patani, R.

10.1101/180372 — neuroscience — Posted on 2017-08-24

363 Bayesian Selection Of Grammar Productions For The Language Of Thought

Romano, S.; Salles, A.; Amalric, M.; Dehaene, S.; Sigman, M.; Figueria, S.

10.1101/141358 — neuroscience — Posted on 2017-08-24

364 Sugar metabolism of the first thermophilic Planctomycetes Thermogutta terrifontis: comparative genomic and transcriptomic approache

Elcheninov, A.; Menzel, P.; Gudbergsdottir, S.; Slesarev, A.; Kadnikov, V.; Krogh, A.; Bonch-Osmolovskaya, E.; Peng, X.; Kublanov, I.

10.1101/179903 — microbiology — Posted on 2017-08-24

365 Prey range and genome evolution of Halobacteriovorax marinus predatory bacteria from an estuary

Enos, B. G.; Anthony, M. K.; DeGiorgis, J. A.; Williams, L. E.

10.1101/180265 — microbiology — Posted on 2017-08-24

366 Differential associations of various depression-related phenotypes with cardiometabolic risks: Identification of shared genetic factors and implications for drug repositioning

Wong, B. C.-F.; Chau, C. K.-L.; Ao, F.-K.; Mo, C.-H.; Wong, S.-Y.; Wong, Y.-H.; So, H.-C.

10.1101/140590 — genomics — Posted on 2017-08-23

367 Universal target-enrichment baits for anthozoan (Cnidaria) phylogenomics: New approaches to long-standing problems

Quattrini, A.; Faircloth, B.; Duenas, L.; Bridge, T.; Brugler, M.; Calixto-Botia, I.; DeLeo, D.; Foret, S.; Herrera, S.; Lee, S.; Miller, D.; Prada, C.; Radis-Baptista, G.; Ramirez-Portilla, C.; Sanchez, J.; Rodriguez, E.; McFadden, C.

10.1101/180067 — genomics — Posted on 2017-08-24

368 Pan-cancer analysis of whole genomes reveals driver rearrangements promoted by LINE-1 retrotransposition in human tumours

Rodriguez-Martin, B.; Alvarez, E. G.; Baez-Ortega, A.; Demeulemeester, J.; Ju, Y. S.; Zamora, J.; Detering, H.; Li, Y.; Contino, G.; Dentro, S. C.; Bruzos, A. L.; Dueso-Barroso, A.; Ardeljan, D.; Tojo, M.; Roberts, N. D.; Blanco, M. G.; Edwards, P. A. W.; Weischenfeldt, J.; Santamarina, M.; Puiggros, M.; Chong, Z.; Chen, K.; Lee, E. A.; Wala, J. A.; Raine, K.; Butler, A.; Waszak, S. M.; Navarro, F. C. P.; Schumacher, S. E.; Monlong, J.; Maura, F.; Bolli, N.; Bourque, G.; Gerstein, M.; Park, P. J.; Berroukhim, R.; Torrents, D.; Korbel, J. O.; Martincorena, I.; Fitzgerald, R. C.; Van Loo, P.; Ka

10.1101/179705 — genomics — Posted on 2017-08-24

369 Rapid MinION metagenomic profiling of the preterm infant gut microbiota to aid in pathogen diagnostics

Leggett, R. M.; Alcon-Giner, C.; Heavens, D.; Caim, S.; Brook, T. C.; Kujawska, M.; Hoyles, L.; Clarke, P.; Hall, L.; Clark, M. D.

10.1101/180406 — genomics — Posted on 2017-08-24

370 Evolutionary genetics of cytoplasmic incompatibility genes cifA and cifB in prophage WO of Wolbachia

Lindsey, A. R. I.; Rice, D. W.; Bordenstein, S. R.; Brooks, A. W.; Bordenstein, S. R.; Newton, I. L. G.

10.1101/180075 — evolutionary biology — Posted on 2017-08-24

371 Effects of partial selfing on the equilibrium genetic variance, mutation load and inbreeding depression under stabilizing selection

Abu Awad, D.; Roze, D.

10.1101/180000 — evolutionary biology — Posted on 2017-08-24

372 Theoretical foundation of the RelTime method for estimating divergence times from variable evolutionary rates

Tamura, K.; Tao, Q.; Kumar, S.

10.1101/180182 — evolutionary biology — Posted on 2017-08-24

373 Unique genetic variants underlie parallel gene expression within a young adaptive radiation despite specialization on highly divergent resources

McGirr, J. A.; Martin, C. H.

10.1101/180190 — evolutionary biology — Posted on 2017-08-24

374 Beyond thermodynamic constraints: Evolutionary history shapes protein sequence variation

Jiang, Q.; Teufel, A.; Jackson, E. L.; Wilke, C. O.

10.1101/180331 — evolutionary biology — Posted on 2017-08-24

375 Coexistence of multiple endemic and pandemic lineages of the rice blast pathogen

Gladieux, P.; Ravel, S.; Rieux, A.; Cros-Arteil, S.; Adreit, H.; Milazzo, J.; Thierry, M.; Fournier, E.; Terauchi, R.; Tharreau, D.

10.1101/179895 — evolutionary biology — Posted on 2017-08-24

376 Coalescent Processes With Skewed Offspring Distributions And Non-Equilibrium Demography

Matuszewski, S.; Hildebrandt, M. E.; Achaz, G.; Jensen, J. D.

10.1101/137497 — evolutionary biology — Posted on 2017-08-24

377 Do latitudinal gradients exist in New Zealand stream invertebrate metacommunities?

Tonkin, J. D.; Death, R. G.; Muotka, T.; Astorga, A.; Lytle, D. A.

10.1101/084673 — ecology — Posted on 2017-08-24

378 Cellular, ultrastructural and molecular analyses of epidermal cell development in the planarian Schmidtea mediterranea

Cheng, L.-C.; Tu, K. C.; Seidel, C. W.; Robb, S. M. C.; Guo, F.; Sanchez Alvarado, A.

10.1101/179986 — developmental biology — Posted on 2017-08-24

379 Genetically Targeted Ratiometric and Activated pH Indicator Complexes (TRApHIC) for Receptor Trafficking

Perkins, L. A.; Yan, Q.; Schmidt, B. F.; Kolodiezyni, D.; Saurabh, S.; Larsen, M. B.; Watkins, S. C.; Kremer, L.; Bruchez, M. P.

10.1101/180141 — cell biology — Posted on 2017-08-24

380 Novel Magnetic Resonance Imaging strategy targeting Neurotensin Receptors in detection of Prostate Cancer

Desai, M. M.; King, J.; Tam, N.; Carraway, R.; Ho, S.-M.; Ferris, C.

10.1101/180042 — cancer biology — Posted on 2017-08-24

381 48-spot single-molecule FRET setup with periodic acceptor excitation

Ingargiola, A.; Segal, M.; Gulinatti, A.; Rech, I.; Labanca, I.; Maccagnani, P.; Ghioni, M.; Weiss, S.; Michalet, X.

10.1101/156182 — biophysics — Posted on 2017-08-23

382 The theoretical molecular weight of NaYF4:RE upconversion nanoparticles

MacKenzie, L. E.; Goode, J. A.; Vakurov, A.; Nampi, P. P.; Saha, S.; Jose, G.; Millner, P. A.

10.1101/114744 — biophysics — Posted on 2017-08-24

383 Structural analyses reveal that the ATG2A-WIPI4 complex functions as a membrane tether for autophagosome biogenesis

Chowdhury, S.; Otomo, C.; Leitner, A.; Ohashi, K.; Aebersold, R.; Lander, G. C.; Otomo, T.

10.1101/180315 — biochemistry — Posted on 2017-08-24

384 Revealing a shortened version of SecA (SecAN) that conceivably functions as a protein-conducting channel in the bacterial cytoplasmic membrane

Jin, F.; Chang, Z.

10.1101/121335 — biochemistry — Posted on 2017-08-24

385 Metabolic Model-Based Analysis of the Emergence of Bacterial Cross-Feeding through Extensive Gene Loss

McNally, C. P.; Borenstein, E.

10.1101/180208 — microbiology — Posted on 2017-08-23

386 Activating the regenerative potential of Müller glia cells in a regeneration-deficient retina

Lust, K.; Wittbrodt, J.

10.1101/180133 — developmental biology — Posted on 2017-08-23

387 Preventing photomorbidity in long-term multi-color fluorescence imaging of S. cerevisiae and S. pombe

Schmidt, G. W.; Cuny, A. P.; Fabian, R.

10.1101/180018 — cell biology — Posted on 2017-08-23

388 NINJA-Associated ERF19 Negatively Regulates Arabidopsis Pattern-Triggered Immunity

Huang, P.-Y.; Zhang, J.; Jiang, B.; Yu, J.-H.; Lu, Y.-P.; Chung, K.; Zimmerli, L.

10.1101/180059 — plant biology — Posted on 2017-08-23

389 The use of hyperimmune chicken reference sera is not appropriate for the validation of influenza pseudotype neutralization assays

Ferrara, F.; Molesti, E.; Scott, S.; Cattoli, G.; Temperton, N. J.

10.1101/180026 — microbiology — Posted on 2017-08-23

390 Differential gene expression in chicken primary B cells infected ex vivo with attenuated and very virulent strains of infectious bursal disease virus (IBDV)

Dulwich, K. L.; Giotis, E. S.; Gray, A.; Nair, V.; Skinner, M. A.; Broadbent, A. J.

10.1101/180158 — microbiology — Posted on 2017-08-23

Roda, F.; Hopkins, R.

10.1101/155986 — plant biology — Posted on 2017-08-23

392 Fundamental limits on dynamic inference from single cell snapshots

Weinreb, C.; Wolock, S.; Tusi, B. K.; Socolovsky, M.; Klein, A. M.

10.1101/170118 — systems biology — Posted on 2017-08-23

393 Structural basis for terminal loop recognition and processing of pri-miRNA-18a by hnRNP A1

Kooshapur, H.; Choudhury, N. R.; Simon, B.; Muehlbauer, M.; Jussupow, A.; Fernandez, N.; Dallmann, A.; Gabel, F.; Camilloni, C.; Michlewski, G.; Caceres, J.; Sattler, M.

10.1101/178855 — molecular biology — Posted on 2017-08-23

394 The nucleoid as a scaffold for the assembly of bacterial signaling complexes

Moine, A.; Espinosa, L.; Martineau, E.; Yaikhomba, M.; Jazleena, P.; Byrne, D.; Biondi, E. G.; Notomista, E.; Brilli, M.; Molle, V.; Gayathri, P.; Mignot, T.; Mauriello, E. M.

10.1101/169912 — microbiology — Posted on 2017-08-23

395 Antisense transcriptional interference mediates condition-specific gene repression in budding yeast

Nevers, A.; Doyen, A.; Malabat, C.; Neron, B.; Kergrohen, T.; Jacquier, A.; Badis, G.

10.1101/169730 — genomics — Posted on 2017-08-23

396 CardioClassifier: demonstrating the power of disease- and gene-specific computational decision support for clinical genome interpretation

Whiffin, N.; Walsh, R.; Govind, R.; Edwards, M.; Ahmad, M.; Zhang, X.; Tayal, U.; Buchan, R.; Midwinter, W.; Wilk, A.; Najgebauer, H.; Francis, C.; Wilkinson, S.; Monk, T.; Brett, L.; Prasad, S. K.; Morris-Rosendahl, D. J.; Barton, P. J.; Edwards, E.; Ware, J. S.; Cook, S. A.

10.1101/180109 — genomics — Posted on 2017-08-23

397 Automating Mendelian randomization through machine learning to construct a putative causal map of the human phenome

Hemani, G.; Bowden, J.; Haycock, P. C.; Zheng, J.; Davis, O.; Flach, P.; Gaunt, T. R.; Davey Smith, G.

10.1101/173682 — epidemiology — Posted on 2017-08-23

398 Cryptic variation in quantitative spatial gene expression in Drosophila

Ali, S.; Signor, S.; Kozlov, K.; Nuzhdin, S.

10.1101/175711 — developmental biology — Posted on 2017-08-23

399 Cdx4 regulates the onset of spinal cord neurogenesis

Joshi, P.; Darr, A. J.; Skromne, I.

10.1101/177469 — developmental biology — Posted on 2017-08-23

400 Deubiquitylation and stabilization of p21 by USP11 is critical for cell cycle progression and DNA damage responses

Deng, T.; Yan, G.; Zhou, Y.; Hu, X.; Li, J.; Hu, J.; Zhang, H.; Feng, P.; Sheng, X.; Chen, J.; Ma, H.; Sun, Y.; Wei, D.; Hu, B.; Liu, J.; Tan, W.; Ye, M.

10.1101/172999 — cell biology — Posted on 2017-08-23

401 Targeted re-sequencing reveals the genomic signatures of multiple barley domestications

Pankin, A.; Altmüller, J.; Becker, C.; von Korff, M.

10.1101/070078 — plant biology — Posted on 2017-08-23

402 Mechanistic Implications of Enhanced Editing by a HyperTRIBE RNA-binding protein

Xu, W.; Rahman, R.; Rosbash, M.

10.1101/156828 — molecular biology — Posted on 2017-08-23

403 Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders

10.1101/135293 — genomics — Posted on 2017-08-23

404 A High HIV-1 Strain Variability in London, UK, Revealed by Full-Genome Analysis: Results from the ICONIC Project

Yebra, G.; Frampton, D.; Gallo Cassarino, T.; Raffle, J.; Hubb, J.; Ferns, B.; Kozlakidis, Z.; Hayward, A.; Kellam, P.; Pillay, D.; Clark, D.; Nastouli, E.; Leigh Brown, A. J.

10.1101/139642 — genomics — Posted on 2017-08-23

405 Extensive genetic differentiation between homomorphic sex chromosomes in the mosquito vector, Aedes aegypti

Fontaine, A.; Filipovic, I.; Fansiri, T.; Hoffmann, A. A.; Cheng, C.; Kirkpatrick, M.; Rasic, G.; Lambrechts, L.

10.1101/060061 — evolutionary biology — Posted on 2017-08-23

406 The theoretical molecular weight of NaYF4:RE upconversion nanoparticles

MacKenzie, L. E.; Goode, J. A.; Vakurov, A.; Nampi, P. P.; Saha, S.; Jose, G.; Millner, P. A.

10.1101/114744 — biophysics — Posted on 2017-08-23

407 Response-Time Behaviors Of Intercellular Communication Network Motifs

Thurley, K.; Wu, L. F.; Altschuler, S. J.

10.1101/136952 — biophysics — Posted on 2017-08-23

408 Positive Sexual Imprinting For Human Eye Color

DeBruine, L. M.; Jones, B. C.; Little, A. C.

10.1101/135244 — animal behavior and cognition — Posted on 2017-08-23

409 Innovations orthogonalization: a solution to the major pitfalls of EEG/MEG "leakage correction"

Pascual-Marqui, R.; Biscay, R. J.; Bosch-Bayard, J.; Faber, P.; Kinoshita, T.; Kochi, K.; Milz, P.; Nishida, K.; Yoshimura, M.

10.1101/178657 — neuroscience — Posted on 2017-08-23

410 Comparison of algorithms for the detection of enteroviruses in stool specimens from children diagnosed with Acute Flaccid Paralysis

Adeniji, J. A.; Ayeni, F. A.; Ibrahim, A.; Tijani, K. A.; Faleye, T. O. C.; Adewumi, M. O.

10.1101/179721 — microbiology — Posted on 2017-08-23

411 Developmental changes within the genetic architecture of social communication behaviour: A multivariate study of genetic variance in unrelated individuals

St. Pourcain, B.; Eaves, L. J.; Ring, S. M.; Fisher, S. E.; Medland, S.; Evans, D. M.; Davey Smith, G.

10.1101/179978 — genetics — Posted on 2017-08-23

412 Higher genetic risk for schizophrenia is associated with living in urban and populated areas

Colodro-Conde, L.; Couvy-Duchesne, B.; Whitfield, J. B.; Streit, F.; Gordon, S.; Rietschel, M.; McGrath, J.; Medland, S. E.; Martin, N. G.

10.1101/179432 — genetics — Posted on 2017-08-23

413 Medical relevance of protein-truncating variants across 337,208 individuals in the UK Biobank study

DeBoever, C.; Tanigawa, Y.; McInnes, G.; Lavertu, A.; Chang, C.; Bustamante, C. D.; Daly, M. J.; Rivas, M. A.

10.1101/179762 — genetics — Posted on 2017-08-23

414 Skip-mers: increasing entropy and sensitivity to detect conserved genic regions with simple cyclic q-grams

Clavijo, B. J.; Garcia Accinelli, G.; Yanes, L.; Barr, K.; Wright, J.

10.1101/179960 — bioinformatics — Posted on 2017-08-23

415 npInv: accurate detection and genotyping of inversions mediated by non-allelic homologous recombination using long read sub-alignment

Shao, H.; Ganesamoorthy, D.; Duarte, T.; Cao, M. D.; Hoggart, C.; Coin, L.

10.1101/178103 — bioinformatics — Posted on 2017-08-23

416 Computational Re-Design of Synthetic Genetic Oscillators for Independent Amplitude and Frequency Modulation

Tomazou, M.; Barahona, M.; Polizzi, K. M.; Stan, G.-B. V.

10.1101/179945 — synthetic biology — Posted on 2017-08-23

417 Concordance Among Indices of Intrinsic Brain Function: Insights from Inter-Individual Variation and Temporal Dynamic

Yan, C.-G.; Yang, Z.; Colcombe, S.; Zuo, X.-N.; Milham, M.

10.1101/048405 — neuroscience — Posted on 2017-08-23

418 Genomic insights and temperature-dependent transcriptional responses of Kosmotoga olearia, a deep-biosphere bacterium that can grow from 20°C to 79°C

Pollo, S. M. J.; Adebusuy, A. A.; Straub, T. J.; Foght, J. M.; Zhaxybayeva, O.; Nesbo, C. L.

10.1101/060053 — microbiology — Posted on 2017-08-23

419 Accurate detection of low-level somatic mutations with technical replication for next-generation sequencing

Kim, J.; Kim, D.; Lim, J. S.; Maeng, J. H.; Son, H.; Kang, H.-C.; Nam, H.; Lee, J. H.; Kim, S.

10.1101/179713 — genomics — Posted on 2017-08-23

420 Draft Genome Sequence of Modestobacter sp. strain VKM Ac-2676 from soil in the area of sharply continental climate

Vasilenko, O. V.; Tarlachkov, S. V.; Starodumova, I. P.; Ariskina, E. V.; Ariskina, K. I.; Avtukh, A. N.; Lysak, L. V.; Telkov, M. V.; Evtushenko, L. I.

10.1101/179697 — genomics — Posted on 2017-08-23

421 Revealing a shortened version of SecA (SecAN) that conceivably functions as a protein-conducting channel in the bacterial cytoplasmic membrane

Jin, F.; Chang, Z.

10.1101/121335 — biochemistry — Posted on 2017-08-23

422 Neotrygon indica sp. nov., the Indian-Ocean blue-spotted maskray (Myliobatoidei, Dasyatidae)

Pavan-Kumar, A.; Kumar, R.; Borsa, P.

10.1101/179911 — zoology — Posted on 2017-08-23

423 A Mathematical model to predict Trichodesmiun spp. bloom during a sewage burst

Santos, G.

10.1101/179853 — systems biology — Posted on 2017-08-23

424 Non-contact measurement of emotional and physiological changes in heart rate from a webcam

Madan, C. R.; Harrison, T.; Mathewson, K. E.

10.1101/179812 — physiology — Posted on 2017-08-23

425 Mortality Data Suggests that Men Are More Fragile but Women Age Faster

Lenart, P.; Kuruczova, D.; Bienertova Vasku, J.

10.1101/179846 — physiology — Posted on 2017-08-23

426 Addiction in a Bounded Rational Model: Role of Environment and its Exploration

Ognibene, D.; Fiore, V. G.; Gu, X.

10.1101/179739 — neuroscience — Posted on 2017-08-23

427 Physiological Gaussian Process Priors for the Hemodynamics in fMRI Analysis

Wilzen, J.; Eklund, A.; Villani, M.

10.1101/179838 — neuroscience — Posted on 2017-08-23

428 Population coding of grasp and laterality-related information in the macaque fronto-parietal network

Michaels, J. A.; Scherberger, H.

10.1101/179184 — neuroscience — Posted on 2017-08-23

429 Demarcating the anatomical structure of the claustrum: piecing together a new functional puddle

Dillingham, C. M.; Frost, B. E.; Jankowski, M. M.; Lambert, M. A.; O'Mara, S. M.

10.1101/179879 — neuroscience — Posted on 2017-08-23

430 Medial prefrontal cortex compresses concept representations through learning

Mack, M. L.; Preston, A. R.; Love, B. C.

10.1101/178145 — neuroscience — Posted on 2017-08-23

431 Neural dynamics of variable grasp movement preparation in the macaque fronto-parietal network

Michaels, J. A.; Dann, B.; Intveld, R. W.; Scherberger, H.

10.1101/179143 — neuroscience — Posted on 2017-08-23

432 Nonivasive prenatal diagnosis of single-gene disorders using droplet digital PCR

Camunas-Soler, J.; Lee, H.; Hudgins, L.; Hintz, S. R.; Blumenfeld, Y. J.; El-Sayed, Y. Y.; Quake, S. R.

10.1101/179804 — genetics — Posted on 2017-08-23

433 A role for the Smc3 hinge domain in the maintenance of sister chromatid cohesion

Robison, B.; Guacci, V.; Koshland, D.

10.1101/179788 — cell biology — Posted on 2017-08-23

434 Ultra-fast super-resolution imaging of biomolecular mobility in tissues

Miller, H.; Cosgrove, J.; Wollman, A. J. M.; O'Toole, P. J.; Coles, M.; Leake, M. C.

10.1101/179747 — biophysics — Posted on 2017-08-23

435 A risk stratification model for lung cancer based on gene coexpression network

Choi, H.; Na, K. J.

10.1101/179770 — bioinformatics — Posted on 2017-08-23

436 Chiron: Translating nanopore raw signal directly into nucleotide sequence using deep learning

Teng, H.; Hall, M. B.; Duarte, T.; Cao, M. D.; Coin, L.

10.1101/179531 — bioinformatics — Posted on 2017-08-23

437 Odor source localization in complex visual environments by fruit flies

Saxena, N.; Natesan, D.; Sane, S. P.

10.1101/179861 — animal behavior and cognition — Posted on 2017-08-23

438 A Large-Scale Binding and Functional Map of Human RNA Binding Proteins

Van Nostrand, E. L.; Freese, P.; Pratt, G. A.; Wang, X.; Wei, X.; Blue, S. M.; Dominguez, D.; Cody, N. A. L.; Olson, S.; Sundararaman, B.; Xiao, R.; Zhan, L.; Bazile, C.; Benoit Bouvrette, L. P.; Chen, J.; Duff, M. O.; Garcia, K.; Gelboin-Burkhart, C.; Hochman, A.; Lambert, N. J.; Li, H.; Nguyen, T. B.; Palden, T.; Rabano, I.; Sathe, S.; Stanton, R.; Louie, A. L.; Aigner, S.; Bergalet, J.; Zhou, B.; Su, A.; Wang, R.; Yee, B. A.; Fu, X.-D.; Lecuyer, E.; Burge, C. B.; Graveley, B.; Yeo, G. W.

10.1101/179648 — genomics — Posted on 2017-08-23

439 Meta-analysis and Commentary: Preemptive Correction of Arteriovenous Access Stenosis

Raimann, J. G.; Waldron, L. D.; Koh, E.; Miller, G. A.; Sor, M. H.; Gray, R. J.; Kotanko, P.

10.1101/179580 — epidemiology — Posted on 2017-08-23

440 Recurring infection with ecologically distinct human papillomavirus (HPV) types explains high prevalence and diversity

Ranjeva, S.; Baskerville, E. B.; Dukic, V.; Villa, L.; Lazcano-Ponce, E.; Giuliano, A. R.; Dwyer, G.; Cobey, S.

10.1101/179341 — epidemiology — Posted on 2017-08-23

441 Evapotranspiration is resilient in the face of land cover and climate change in a humid temperate catchment

Hamilton, S. K.; Hussain, M. Z.; Lowrie, C.; Basso, B.; Robertson, G. P.

10.1101/075598 — ecology — Posted on 2017-08-22

442 Nanoparticle-Guided Biomolecule Delivery for Transgene Expression and Gene Silencing in Mature Plants

Demirer, G. S.; Chang, R.; Zhang, H.; Chio, L.; Landry, M. P.

10.1101/179549 — plant biology — Posted on 2017-08-22

443 Bayesian Efficient Coding

Park, I. M.; Pillow, J. W.

10.1101/178418 — neuroscience — Posted on 2017-08-22

444 Brain state and polarity dependent modulation of brain networks by transcranial direct current stimulation

Li, L. M.; Violante, I.; Leech, R.; Ross, E.; Hampshire, A.; Opitz, A.; Rothwell, J.; Carmichael, D.; Sharp, D. J.

10.1101/179556 — neuroscience — Posted on 2017-08-22

445 Modeling of Epigenetic Modification-Induced Changes in CRX-dependent Genes cis-Regulatory Elements

Hossain, R. A.; Dunham, N. R.; Harris, M. E.; Hutchinson, T. L.; Kidd, J. M.; Kohler, L. R.; Salamon, G. J.; Schmidt, A. L.; Thomas, M. D.; Enke, R.; Berndsen, C. E.

10.1101/179523 — molecular biology — Posted on 2017-08-22

446 Active ribosome profiling with RiboLace

Clamer, M.; Tebaldi, T.; Lauria, F.; Bernabo, P.; Gomez-Biagi, R. F.; Perenthaler, E.; Gubert, D.; Pasquardini, L.; Guella, G.; Groen, E. J. N.; Gillingwater, T. H.; Quattrone, A.; Viero, G.

10.1101/179671 — molecular biology — Posted on 2017-08-22

447 Role for Ribosome-Associated Complex and Stress-Seventy subfamily B (RAC-Ssb) in integral membrane protein translation

Acosta-Sampson, L.; Döring, K.; Lin, Y.; Yu, V.; Bukau, B.; Kramer, G.; Cate, J.

10.1101/179564 — molecular biology — Posted on 2017-08-22

448 Spatial Genome Organization as a Framework for Somatic Alterations in Human Cancer

Akdemir, K. C.; Li, Y.; Verhaak, R. G.; Beroukhim, R.; Cambell, P.; Chin, L.; Futreal, A.

10.1101/179176 — genomics — Posted on 2017-08-22

449 Piggy: A Rapid, Large-Scale Pan-Genome Analysis Tool for Intergenic Regions in Bacteria

Thorpe, H. A.; Bayliss, S. C.; Sheppard, S. K.; Feil, E. J.

10.1101/179515 — genomics — Posted on 2017-08-22

450 Zinc detoxification: a functional genomics and transcriptomics analysis in Drosophila melanogaster cultured cells

Mohr, S.; Rudd, K.; Hu, Y.; Song, W. R.; Gilly, Q.; Buckner, M.; Housden, B. E.; Kelley, C.; Zirin, J.; Tao, R.; Amador, G.; Sierzputowska, K.; Comjean, A.; Perrimon, N.

10.1101/179598 — genetics — Posted on 2017-08-22

451 Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice

Hirose, M.; Schilf, P.; Gupta, Y.; Zarse, K.; Kuenstner, A.; Busch, H.; Yin, J.; Wright, M. N.; Ziegler, A.; Vallier, M.; Belheouane, M.; Baines, J. F.; Tautz, D.; Johann, K.; Oelkrug, R.; Mittag, J.; Lehnert, H.; Othman, A.; Joehren, O.; Schwaninger, M.; Prehn, C.; Adamski, J.; Shima, K.; Rupp, J.; Haesler, R.; Fuellen, G.; Koehling, R.; Ristow, M.; Ibrahim, S. M.

10.1101/179622 — genetics — Posted on 2017-08-22

452 Identification of Iridoid Synthases from Nepeta species: Iridoid cyclization does not determine nepetalactone stereochemistry

Sherden, N. H.; Lichman, B.; Caputi, L.; Zhao, D.; Kamileen, M. O.; Buell, C. R.; O'Connor, S.

10.1101/179572 — biochemistry — Posted on 2017-08-22

453 Tadpole-like conformations of huntingtin exon 1 with expanded polyglutamine engenders novel interactions in cells

Newcombe, E. A.; Ruff, K. M.; Sethi, A.; Ormsby, A.; Ramdzan, Y. M.; Fox, A.; Purcell, A. W.; Gooley, P. R.; Pappu, R. V.; Hatters, D. M.

10.1101/179663 — biochemistry — Posted on 2017-08-22

454 Helpers increase daily survival rate of Southern Lapwing (Vanellus chilensis) nests during the incubation stage

Santos, E. S. A.; Macedo, R. H.

10.1101/179606 — animal behavior and cognition — Posted on 2017-08-22

455 Data-driven subtyping of executive function related behavioural problems in children

Bathelt, J.; Holmes, J.; the CALM team, ; Astle, D. E.

10.1101/158949 — neuroscience — Posted on 2017-08-22

456 Identification of an Essential IL15-STAT1-IRX3 Prosurvival Pathway in T Lymphocytes with Therapeutic Implications

Persengiev, S.

10.1101/178939 — molecular biology — Posted on 2017-08-22

457 Phototaxis as a Collective Phenomenon in Cyanobacterial Colonies

Varuni, P.; Menon, S. N.; Menon, G. I.

10.1101/155622 — microbiology — Posted on 2017-08-22

458 Sex Chromosome Dosage Effects On Gene Expression In Humans

Raznahan, A.; Parikshak, N.; Chandran, V.; Blumenthal, J.; Clasen, L.; Alexander-Bloch, A.; Zinn, A.; Wangsa, D.; Wise, J.; Murphy, D.; Bolton, P.; Ried, T.; Ross, J.; Giedd, J.; Geschwind, D.

10.1101/137752 — genomics — Posted on 2017-08-22

459 A Bayesian Framework for Multiple Trait Colocalization from Summary Association Statistics

Giambartolomei, C.; Zhenli Liu, J.; Zhang, W.; Hauberg, M.; Shi, H.; Boocock, J.; Pickrell, J.; Jaffe, A. E.; CommonMind Consortium, ; Pasaniuc, B.; Roussos, P.

10.1101/155481 — genomics — Posted on 2017-08-22

460 Analyzing contentious relationships and outlier genes in phylogenomics

Walker, J. F.; Brown, J. W.; Smith, S. A.

10.1101/115774 — evolutionary biology — Posted on 2017-08-22

461 Using mitochondrial genomes to infer phylogenetic relationships among the oldest extant winged insects (Palaeoptera)

Rutschmann, S.; Chen, P.; Zhou, C.; Monaghan, M. T.

10.1101/164459 — evolutionary biology — Posted on 2017-08-22

462 Size control in mammalian cells involves modulation of both growth rate and cell cycle duration

Cadart, C.; Monnier, S.; Grilli, J.; Attia, R.; Terriac, E.; Baum, B.; Cosentino-Lagomarsino, M.; Piel, M.

10.1101/152728 — cell biology — Posted on 2017-08-22

463 Evidence for time division multiplexing of multiple simultaneous items in a sensory coding bottleneck

Caruso, V. C.; Mohl, J. T.; Glynn, C.; Lee, J.; Willett, S. M.; Zaman, A.; Estrada, R.; Tokdar, S.; Groh, J. M.

10.1101/107185 — neuroscience — Posted on 2017-08-22

464 Genomic and structural features of the Yellow Fever virus from the 2016-2017 Brazilian outbreak

Gomez, M. M.; de Abreu, F. V. S.; dos Santos, A. A. C.; de Mello, I. S.; Santos, M. P.; Ribeiro, I. P.; Ferreira-de-Brito, A.; de Miranda, R. M.; de Castro, M. G.; Ribeiro, M. S.; Laperriere, R. d. C.; Aguiar, S. F.; Meira, G. L. S.; Antunes, D.; Torres, P. H. M.; Vicente, A. C. P.; Guimaraes, A. C. R.; Caffarena, E. R.; Bello, G.; Lourenco-de-Oliveira, R.; Bonaldo, M. C.

10.1101/179481 — microbiology — Posted on 2017-08-22

465 PathCORE: identifying and visualizing globally co-occurring pathways in large transcriptomic compendia

Chen, K. M.; Tan, J.; Way, G. P.; Doing, G.; Hogan, D. A.; Greene, C. S.

10.1101/147645 — bioinformatics — Posted on 2017-08-22

466 Issues in the statistical detection of data fabrication and data errors in the scientific literature: simulation study and reanalysis of Carlisle, 2017

Piraino, S. W.

10.1101/179135 — scientific communication and education — Posted on 2017-08-22

467 The neural encoding of information prediction errors during non-instrumental information seeking

Brydevall, M.; Bennett, D.; Murawski, C.; Bode, S.

10.1101/179507 — neuroscience — Posted on 2017-08-22

468 White Matter and Social Cognition

Wang, Y.; Metoki, A.; Alm, K. H.; Olson, I. R.

10.1101/179473 — neuroscience — Posted on 2017-08-22

469 Mapping movement, mood, motivation, and mentation in the subthalamic nucleus

Gourisankar, A.; Eisenstein, S. A.; Trapp, N. T.; Koller, J. M.; Campbell, M. C.; Ushe, M.; Perlmutter, J. S.; Hershey, T.; Black, K. J.

10.1101/168302 — neuroscience — Posted on 2017-08-22

470 A Bayesian Framework for Multiple Trait Colocalization from Summary Association Statistics

Giambartolomei, C.; Zhenli Liu, J.; Zhang, W.; Hauberg, M.; Shi, H.; Boocock, J.; Pickrell, J.; Jaffe, A. E.; CommonMind Consortium, ; Pasaniuc, B.; Roussos, P.

10.1101/155481 — genomics — Posted on 2017-08-22

471 Microscopic Dissipative Structuring at the Origin of Life

Michaelian, K.

10.1101/179382 — biophysics — Posted on 2017-08-22

472 Spot-On: robust model-based analysis of single-particle tracking experiments

Hansen, A. S.; Woringer, M.; Grimm, J. B.; Lavis, L. D.; Tjian, R.; Darzacq, X.

10.1101/171983 — biophysics — Posted on 2017-08-22

473 Costing ‘the’ MTD

Norris, D. C.

10.1101/150821 — pharmacology and toxicology — Posted on 2017-08-22

474 Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naive B cells, and facilitates recruitment of transcription factors to the viral genome.

Szymula, A.; Palermo, R. D.; Groves, I. J.; Ba abdullah, M.; Holder, B. S.; White, R. E.

10.1101/176099 — microbiology — Posted on 2017-08-22

475 Receptor Uptake Arrays For Vitamin B12, Siderophores And Glycans Shape Bacterial Communities

Frank, S. A.

10.1101/144691 — microbiology — Posted on 2017-08-22

476 Tim-3 co-stimulation promotes short-term effector T cells, restricts memory precursors and is dispensable for T cell exhaustion

Avery, L.; Szymczak-Workman, A. L.; Kane, L. P.

10.1101/179002 — immunology — Posted on 2017-08-22

477 Heart-Specific Activin Signaling Promotes Cardiomyopathy And Organismal Aging Through Autophagy Inhibition

Chang, K.; Kang, P.; Liu, Y.; Huang, K.; Taylor, E.; Bodmer, R.; Ocorr, K.; Bai, H.

10.1101/139360 — genetics — Posted on 2017-08-22

478 Genome-wide association study of habitual physical activity in over 277,000 UK Biobank participants identifies novel variants and genetic correlations with chronotype and obesity-related traits.

Klimentidis, Y. C.; Raichlen, D. A.; Bea, J.; Garcia, D. O.; Mandarino, L. J.; Alexander, G. A.; Chen, Z.; Going, S. B.

10.1101/179317 — genetics — Posted on 2017-08-22

479 Modularity Facilitates Flexible Tuning Of Plastic And Evolutionary Gene Expression Responses During Early Divergence

Makinen, H.; Savilammi, T.; Papakostas, S.; Leder, E.; Vollestad, A.; Primmer, C.

10.1101/179424 — evolutionary biology — Posted on 2017-08-22

480 Does red eye fluorescence in marine fish stand out? In situ and in vivo measurements at two depths

Harant, U. K.; Wehrberger, F.; Griessler, T.; Meadows, M. G.; Champ, C. M.; Michiels, N. K.

10.1101/174045 — ecology — Posted on 2017-08-22

481 IVIM parameters have good scan-rescan reproducibility when evidential motion contaminated and poorly fitted image data are removed

Chevallier, O.; Zhou, N.; He, J.; Loffroy, R.; Wang, Y.-X.

10.1101/179440 — biophysics — Posted on 2017-08-22

482 MRIQC: Advancing the Automatic Prediction of Image Quality in MRI from Unseen Sites

Esteban, O.; Birman, D.; Schaer, M.; Koyejo, O. O.; Poldrack, R. A.; Gorgolewski, K. J.

10.1101/111294 — bioinformatics — Posted on 2017-08-22

483 Low rate of index hopping on the Illumina HiSeq X platform

van der Valk, T.; Vezzi, F.; Ormestad, M.; Dalen, L.; Guschanski, K.

10.1101/179028 — bioinformatics — Posted on 2017-08-22

484 Measuring Biotherapeutic Viscosity and Degradation On-Chip with Particle Diffusometry

Clayton, K. N.; Lee, D. H.; Wereley, S. T.; Kinzer-Ursem, T. L.

10.1101/179101 — bioengineering — Posted on 2017-08-22

485 Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits

Raab, J.; Runge, J. S.; Spear, C. C.; Magnuson, T.

10.1101/178848 — genomics — Posted on 2017-08-22

486 Generation and validation of a floxed FosB mouse line

Ohnishi, Y. N.; Eagle, A. L.; Ohnishi, Y. H.; Cahill, M. E.; Wirtz, A. J.; Robison, A. J.; Nestler, E. J.

10.1101/179309 — genetics — Posted on 2017-08-22

487 Sequence and structural diversity of mouse Y chromosomes

Morgan, A. P.; Pardo Manuel de Villena, F.

10.1101/096297 — genetics — Posted on 2017-08-22

488 PDB-NMA of a Protein Homodimer Reproduces Distinct Experimental Motility Asymmetry

Tirion, M.; ben-Avraham, D.

10.1101/179333 — biophysics — Posted on 2017-08-22

489 SeroBA: rapid high-throughput serotyping of Streptococcus pneumoniae from whole genome sequence data

Epping, L.; Hunt, M.; van Tonder, A. J.; Gladstone, R. A.; The Global Pneumococcal Sequencing consortium, ; Bentley, S. D.; Page, A. J.; Keane, J. A.

10.1101/179465 — bioinformatics — Posted on 2017-08-22

490 Development of honeybee waggle dance and its differences between recruits and scouts

Ai, H.; Kobayashi, Y.; Matake, T.; Takahashi, S.; Hashimoto, K.; Maeda, S.; Tsuruta, N.

10.1101/179408 — animal behavior and cognition — Posted on 2017-08-22

491 Global transcriptome analysis of Aedes aegypti mosquitoes in response to Zika virus infection

Etebari, K.; Hegde, S.; Saldana, M. A.; Widen, S. G.; Wood, T. G.; Asgari, S.; Hughes, G. L.

10.1101/179416 — microbiology — Posted on 2017-08-22

492 Multiple tasks viewed from the neural manifold: Stable control of varied behavior

Gallego, J. A.; Perich, M. G.; Naufel, S. N.; Ethier, C.; Solla, S. A.; Miller, L. E.

10.1101/176081 — neuroscience — Posted on 2017-08-21

Im, H. Y.; Adams, R. B.; Cushing, C. A.; Boshyan, J.; Ward, N.; Kveraga, K.

10.1101/179051 — neuroscience — Posted on 2017-08-21

494 Supplement comprising of laccase and citric acid as an alternative for antibiotics - in vitro triggers of melanin production

Chaali, M.; Lecka, J.; Suresh, G.; Salem, M.; Brar, S. K.; Hernandez-Galan, L.; Sevigny, J.; Avalos-Ramirez, A.

10.1101/179291 — immunology — Posted on 2017-08-21

495 Divergent genome evolution caused by regional variation in DNA gain and loss between human and mouse

Buckley, R. M.; Kortschak, R. D.; Adelson, D. L.

10.1101/179200 — evolutionary biology — Posted on 2017-08-21

496 Insulin resistance in cavefish as an adaptation to a nutrient-limited environment

Aspiras, A.; Riddle, M.; Gaudenz, K.; Peuss, R.; Sung, J.; Martineau, B.; Peavey, M.; Box, A.; Tabin, J. A.; McGaugh, S.; Borowsky, R.; Tabin, C. J.; Rohner, N.

10.1101/179069 — evolutionary biology — Posted on 2017-08-21

497 Does no-till agriculture limit crop yields?

Tanadini, M.; Mehrabi, Z.

10.1101/179358 — ecology — Posted on 2017-08-21

498 PI3K regulates intraepithelial cell positioning through Rho GTP-ases in the developing neural tube.

Torroba, B.; Herrera, A.; Menendez, A.; Pons, S.

10.1101/179325 — cell biology — Posted on 2017-08-21

499 Identification of copy number variations and translocations in cancer cells from Hi-C data

Chakraborty, A.; Ay, F.

10.1101/179275 — bioinformatics — Posted on 2017-08-21

500 Genetic and real-world clinical data, combined with empirical validation, nominate JAK-STAT signalling as a target for Alzheimer’s Disease therapeutic development

Nevado-Holgado, A. J.; Ribe, E.; Thei, L.; Furlong, L.; Angel-Mayer, M.; Quan, J.; Richardson, J. C.; Cavanagh, J.; NIMA Consortium, ; Lovestone, S.

10.1101/179267 — bioinformatics — Posted on 2017-08-21

501 Best practices for genome-wide RNA structure analysis: combination of mutational profiles and drop-off information

Novoa, E. M.; Beaudoin, J.-D.; Giraldez, A. J.; Mattick, J. S.; Kellis, M.

10.1101/176883 — bioinformatics — Posted on 2017-08-21

502 Case report: intermittent fasting and probiotic yogurt consumption are associated with reduction of serum alpha-N-acetylgalactosaminidase and increased urinary excretion of lipophilic toxicants

Blythe, J.; Pacini, S.

10.1101/177774 — pharmacology and toxicology — Posted on 2017-08-21

503 Heterogeneity Within the Frontoparietal Control Network and its Relationship to the Default and Dorsal Attention Networks

Dixon, M. L.; De La Vega, A.; Mills, C.; Andrews-Hanna, J.; Spreng, R. N.; Cole, M.; Christoff, K.

10.1101/178863 — neuroscience — Posted on 2017-08-21

504 Domain-Specific Patterns of Activity Support Metacognition in Human Prefrontal Cortex

Morales, J.; Lau, H.; Fleming, S. M.

10.1101/172445 — neuroscience — Posted on 2017-08-21

505 LTR_retriever: A Highly Accurate And Sensitive Program For Identification Of LTR Retrotransposons

Ou, S.; Jiang, N.

10.1101/137141 — genomics — Posted on 2017-08-21

506 Use of Continuous Traits Can Improve Morphological Phylogenetics

Parins-Fukuchi, C.

10.1101/121343 — evolutionary biology — Posted on 2017-08-21

507 How Many Females Are There? Cheating and Female Dispersion Can Explain Mating Behavior Evolution

Valerio Gomes, B.; Menezes Guimaraes, D.; Szczupak, D.; Neves, K.

10.1101/171330 — ecology — Posted on 2017-08-21

508 Comparing colours using visual models

Maia, R.; White, T.

10.1101/175992 — animal behavior and cognition — Posted on 2017-08-21

509 A genome-scale study of metabolic complementation in endosymbiotic consortia: the case of the cedar aphid

Ponce-de-Leon, M.; Tamarit, D.; Calle-Espinosa, J.; Mori, M.; Latorre, A.; Montero, F.; Pereto, J.

10.1101/179127 — systems biology — Posted on 2017-08-21

510 Single-cell RNA-seq reveals intrinsic and extrinsic regulatory heterogeneity in yeast responding to stress

Gasch, A. P.; Yu, F. B.; Hose, J.; Escalante, L. E.; Place, M.; Bacher, R.; Kanbar, J.; Ciobanu, D.; Sandor, L.; Grigoriev, I.; Kendziorski, C.; Quake, S. R.; McClean, M. N.

10.1101/179093 — systems biology — Posted on 2017-08-21

511 Limited role of differential fractionation in genome content variation and function in maize (Zea mays L.) inbred lines

Brohammer, A. B.; Kono, T. J. Y.; Springer, N. M.; McGaugh, S. E.; Hirsch, C. N.

10.1101/179119 — plant biology — Posted on 2017-08-21

512 Olfactory coding in the turbulent realm

Jacob, V.; Monsempes, C.; Rospars, J.-P.; Masson, J.-B.; Lucas, P.

10.1101/179085 — neuroscience — Posted on 2017-08-21

513 Progressive reconfiguration of resting-state brain networks as psychosis develops: Preliminary results from the North American Prodrome Longitudinal Study (NAPLS) consortium

Cao, H.; Chung, Y.; McEwen, S.; Bearden, C.; Addington, J.; Goodyear, B.; Cadenhead, K.; Mirzakhanian, H.; Cornblatt, B.; Olvet, D.; Mathalon, D.; McGlashan, T.; Perkins, D.; Belger, A.; Seidman, L.; Thermenos, H.; Tsuang, M.; van Erp, T.; Walker, E.; Hamann, S.; Anticevic, A.; Woods, S.; Cannon, T.

10.1101/179242 — neuroscience — Posted on 2017-08-21

514 Multimodal Surface Matching with Higher-Order Smoothness Constraints

Robinson, E. C.; Garcia, K.; Glasser, M. F.; Chen, Z.; Coalson, T. S.; Makropoulos, A.; Bozek, J.; Wright, R.; Schuh, A.; Webster, M.; Hutter, J.; Price, A.; Cordero-Grande, L.; Hughes, E.; Tusor, N.; Bayly, P. V.; Van Essen, D. C.; Edwards, A. D.; Smith, S. M.; Hajnal, J.; Jenkinson, M.; Glocker, B.; Rueckert, D.

10.1101/178962 — neuroscience — Posted on 2017-08-21

515 Natural variation at FLOWERING LOCUS T2 mediates local adaptation in a key life history trait in European aspen

Wang, J.; Ding, J.; Tan, B.; Robinson, K. M.; Michelson, I. H.; Johansson, A.; Nystedt, B.; Scofield, D. G.; Nilsson, O.; Jansson, S.; Street, N. R.; Ingvarsson, P. K.

10.1101/178921 — evolutionary biology — Posted on 2017-08-21

516 The importance and adaptive value of life history evolution for metapopulation dynamics

Bonte, D.; Bafort, Q.

10.1101/179234 — evolutionary biology — Posted on 2017-08-21

517 Genetic fingerprinting of salmon louse (Lepeophtheirus salmonis) populations in the North-East Atlantic using a random forest classification approach

Jacobs, A.; De Noia, M.; Praebel, K.; Kanstad-Hanssen, O.; Paterno, M.; Jackson, D.; McGinnity, P.; Sturm, A.; Elmer, K. R.; Llewellyn, M. S.

10.1101/179218 — ecology — Posted on 2017-08-21

518 A minimally sufficient model for rib proximal-distal patterning based on genetic analysis and agent-based simulations

Fogel, J.; Lakeland, D.; Mah, I. K.; Mariani, F.

10.1101/179077 — developmental biology — Posted on 2017-08-21

519 Microtubule dynamics regulates mitochondrial fission

Mehta, K.; Chug, M. K.; Jhunjhunwala, S.; Ananthanarayanan, V.

10.1101/178913 — cell biology — Posted on 2017-08-21

520 Cancer associated fibroblasts and alectinib switch the evolutionary games that non-small cell lung cancer plays

Kaznatcheev, A.; Peacock, J.; Basanta, D.; Marusyk, A.; Scott, J. G.

10.1101/179259 — cancer biology — Posted on 2017-08-21

521 R2DGC: Threshold-free peak alignment and identification for 2D gas chromatography mass in R

Ramaker, R. C.; Gordon, E.; Cooper, S. J.

10.1101/179168 — bioinformatics — Posted on 2017-08-21

522 Effect of ligands on stability of H-Ras GTPase

Kovrigina, E. A.; O'Connor, C.; Kovrigin, E. L.

10.1101/179283 — biochemistry — Posted on 2017-08-21

523 Fast and Powerful Genome Wide Association Analysis of Dense Genetic Data with High Dimensional Imaging Phenotypes

Ganjgahi, H.; Winkler, A. M.; Glahn, D. C.; Blangero, J.; Donohue, B.; Kochunov, P.; Nichols, T. E.

10.1101/179150 — genetics — Posted on 2017-08-21

524 Using Outliers in Freesurfer Segmentation Statistics to Identify Cortical Reconstruction Errors in Structural Scans

Waters, A.; Mace, R.; Sawyer, K.; Gansler, D.

10.1101/176818 — neuroscience — Posted on 2017-08-21

525 Maternal X chromosome upregulation in both sexes initiates dosage compensation evolution

Muyle, A.; Zemp, N.; Fruchard, C.; Cegan, R.; Vrana, J.; Deschamps, C.; Tavares, R.; Picard, F.; Hobza, R.; Widmer, A.; Marais, G.

10.1101/179044 — evolutionary biology — Posted on 2017-08-21

526 Transgene-free hematopoietic stem and progenitor cells from human induced pluripotent stem cells

Guyonneau-Harmand, L.; L'Homme, B.; Birebent, B.; Desterke, C.; Chevallier, N.; Garcon, L.; Lapillonne, H.; Benderitter, M.; Delhommeau, F.; Jaffredo, T.; Chapel, A.; Douay, L.

10.1101/177691 — cell biology — Posted on 2017-08-21

527 Direct and Inverted Repeat stimulated excision (DIRex): Simple, single-step, and scar-free mutagenesis of bacterial genes

Nasvall, J.

10.1101/149534 — synthetic biology — Posted on 2017-08-21

528 Control of lineage-specific gene expression by functionalized gRNA barcodes

Al'Khafaji, A.; Brock, A.

10.1101/178897 — synthetic biology — Posted on 2017-08-21

529 A dual sgRNA approach for functional genomics in Arabidopsis thaliana

Pauwels, L.; De Clercq, R.; Goossens, J.; Inigo, S.; Williams, C.; Ron, M.; Britt, A.; Goossens, A.

10.1101/172676 — plant biology — Posted on 2017-08-21

530 Circuit robustness to temperature perturbation is altered by neuromodulators

Haddad, S. A.; Marder, E.

10.1101/178764 — neuroscience — Posted on 2017-08-21

531 Design and specificity of long ssDNA donors for CRISPR-based knock-in

Li, H.; Beckman, K. A.; Pessino, V.; Huang, B.; Weissman, J. S.; Leonetti, M. D.

10.1101/178905 — molecular biology — Posted on 2017-08-21

532 PANINI: Pangenome Neighbor Identification for Bacterial Populations

Abudahab, K.; Prada, J. M.; Yang, Z.; Bentley, S. D.; Croucher, N. J.; Corander, J.; Aanensen, D. M.

10.1101/174409 — microbiology — Posted on 2017-08-21

533 Building a genome browser with GIVE

Cao, X.; Yan, Z.; Wu, Q.; Zheng, A.; Zhong, S.

10.1101/177832 — bioinformatics — Posted on 2017-08-21

534 Detection of whole-field luminance changes by superficial interneurons in the zebrafish tectum

Barker, A. J.; Helmbrecht, T. O.; Grob, A. A.; Baier, H.

10.1101/178970 — neuroscience — Posted on 2017-08-21

535 Developmental cognitive neuroscience using Latent Change Score models: A tutorial and applications

Kievit, R.; Brandmaier, A.; Ziegler, G.; van Harmelen, A.-L.; de Mooij, S.; Moutoussis, M.; Goodyer, I.; Bullmore, E.; Jones, P.; Fonagy, P.; NSPN Consortium, ; Lindenberger, U.; Dolan, R.

10.1101/110429 — neuroscience — Posted on 2017-08-21

536 Heterogeneity Within the Frontoparietal Control Network and its Relationship to the Default and Dorsal Attention Networks

Dixon, M. L.; de la Vega, A.; Mills, C.; Andrews-Hanna, J.; Spreng, R. N.; Cole, M.; Christoff, K.

10.1101/178863 — neuroscience — Posted on 2017-08-21

537 Identification of an Essential IL15-STAT1-IRX3 Prosurvival Pathway in T Lymphocytes with Therapeutic Implications

Persengiev, S.

10.1101/178939 — molecular biology — Posted on 2017-08-21

538 Metagenomic sequencing to replace semi-quantitative urine culture for detection of urinary tract infections: a proof of concept

Janes, V. A.; Matamoros, S.; Willemse, N.; Visser, C. E.; de Wever, B.; Jakobs, M. E.; Subramanian, P.; Hasan, N. A.; Colwell, R. R.; de Jong, M. D.; Schultsz, C.

10.1101/178178 — microbiology — Posted on 2017-08-21

539 Identification and kinetics characterization of a wax ester hydrolase from a feather-degrading actinomycete

Barcus, M.; Mizrachi, D.; Lei, X. G.

10.1101/178673 — microbiology — Posted on 2017-08-21

540 CTCF mediated genome architecture regulates the dosage of mitotically stable mono-allelic expression of autosomal genes

Chandradoss, K. R.; Sandhu, K. S.

10.1101/178749 — genomics — Posted on 2017-08-21

541 The genetic basis of human brain structure and function: 1,262 genome-wide associations found from 3,144 GWAS of multimodal brain imaging phenotypes from 9,707 UK Biobank participants

Elliott, L.; Sharp, K.; Alfaro-Almagro, F.; Douaud, G.; Miller, K.; Marchini, J.; Smith, S.

10.1101/178806 — genetics — Posted on 2017-08-21

542 Genomic prediction reveals significant non-additive effects for growth in hybrid Eucalyptus

Tan, B.; Grattapaglia, D.; Wu, H. X.; Ingvarsson, P. K.

10.1101/178160 — genetics — Posted on 2017-08-21

543 Identification And Characterization Of Domesticated Bacterial Transposases

Bertels, F.; Gallie, J.; Rainey, P. B.

10.1101/119735 — evolutionary biology — Posted on 2017-08-21

544 A National Estimate of the Health and Cost Burden of Escherichia coli Bacteraemia in the Hospital Setting: The Importance of Antibiotic Resistance

Naylor, N. R.; Pouwels, K. B.; Hope, R.; Green, N.; Henderson, K. L.; Knight, G. M.; Atun, R.; Robotham, J. V.; Deeny, S.

10.1101/153775 — epidemiology — Posted on 2017-08-21

545 Cryo-ET reveals nucleosome reorganization in condensed mitotic chromosomes in vivo

Cai, S.; Chen, C.; Tan, Z. Y.; Shi, J.; Gan, L.

10.1101/178996 — cell biology — Posted on 2017-08-21

546 Lipid perturbation compromises UPR-mediated ER homeostasis as a result of premature degradation of membrane proteins

Ng, B. S. H.; Shyu, P. T.; Chaw, R.; Seah, Y. L.; Thibault, G.

10.1101/178947 — cell biology — Posted on 2017-08-21

547 Mitochondria Are Physiologically Maintained At Close To 50 °C

Chretien, D.; Benit, P.; Ha, H.-H.; Keipert, S.; El-Khoury, R.; Chang, Y.-T.; Jastroch, M.; Jacobs, H.; Rustin, P.; Rak, M.

10.1101/133223 — cell biology — Posted on 2017-08-21

548 Stromal Reactivity Differentially Drives Tumor Cell Evolution and Prostate Cancer Progression

Frankenstein, Z.; Basanta, D.; Franco, O. E.; Gao, Y.; Javier, R. A.; Strand, D. W.; Lee, M.; Hayward, S. W.; Ayala, G.; Anderson, A. R. A.

10.1101/159616 — cancer biology — Posted on 2017-08-21

549 SQANTI: extensive characterization of long read transcript sequences for quality control in full-length transcriptome identification and quantification

Tardaguila, M.; de la Fuente, L.; Marti, C.; Pereira, C.; Pardo-Palacios, F. J.; del Risco, H.; Ferrell, M.; Mellado, M.; Macchietto, M.; Verheggen, K.; Edelmann, M.; Ezkurdia, I.; Vazquez, J.; Tress, M.; Mortazavi, A.; Martens, L.; Rodriguez-Navarro, S.; Moreno, V.; Conesa, A.

10.1101/118083 — bioinformatics — Posted on 2017-08-21

550 LOGAN: A framework for LOssless Graph-based ANalysis of high throughput sequence data

Bolger, A. M.; Denton, A. K.; Bolger, M. E.; Usadel, B.

10.1101/175976 — bioinformatics — Posted on 2017-08-21

551 Taking a semi-local dynamic snapshot as a possibility for local homing in initially naive bumblebees

Lobecke, A.; Kern, R.; Egelhaaf, M.

10.1101/178988 — animal behavior and cognition — Posted on 2017-08-21

552 The role of stimulus similarity on the summation effect in human causal learning

Perez, O. D.; San Martin, R.; Soto, F. A.

10.1101/178954 — animal behavior and cognition — Posted on 2017-08-21

553 The maternal genetic make-up of the Iberian Peninsula between the Neolithic and the Early Bronze Age

Szecsenyi-Nagy, A.; Roth, C.; Brandt, G.; Rihuete-Herrada, C.; Tejedor-Rodriguez, C.; Held, P.; Garcia-Martinez-de-Lagran, I.; Arcusa Magallon, H.; Zesch, S.; Knipper, C.; Banffy, E.; Friedrich, S.; Meller, H.; Bueno-Ramirez, P.; Barroso Bermejo, R.; de Balbin Behrmann, R.; Herrero-Coral, A. M.; Flores Fernandez, R.; Alonso Fernandez, C.; Jimenez Echevarria, J.; Rindlisbacher, L.; Oliart, C.; Fregeiro, M.-I.; Soriano, I.; Vincente, O.; Mico, R.; Lull, V.; Soler Diaz, J.; Lopez Padilla, J. A.; Roca de Togores Munoz, C.; Hernandez Perez, M. S.; Jover Maestre, F. J.; Lomba Maurandi, J.; Aviles Fe

10.1101/106963 — genetics — Posted on 2017-08-21

554 Dynamic clustering of dynamin-amphiphysin rings regulates membrane constriction and fission coupled with GTP hydrolysis

Takeda, T.; Kozai, T.; Yang, H.; Ishikuro, D.; Seyama, K.; Kumagai, Y.; Abe, T.; Yamada, H.; Uchihashi, T.; Ando, T.; Takei, K.

10.1101/167262 — biophysics — Posted on 2017-08-20

555 Notes On Synthesis Of Perdeutero-5-13C,5,5,5-Trifluoroisoleucine VI

Naugler, D.; Prosser, R. S.

10.1101/140681 — molecular biology — Posted on 2017-08-20

556 A powerful approach to estimating annotation-stratified genetic covariance using GWAS summary statistics

Lu, Q.; Li, B.; Ou, D.; Erlendsdottir, M.; Powles, R. L.; Jiang, T.; Hu, Y.; Chang, D.; Jin, C.; Dai, W.; He, Q.; Liu, Z.; Mukherjee, S.; Crane, P. K.; Zhao, H.

10.1101/114561 — genetics — Posted on 2017-08-20

557 Abnormal cell sorting underlies the unique X-linked inheritance of PCDH19 Epilepsy

Pederick, D.; Richards, K.; Piltz, S.; Mandelstam, S.; Dale, R.; Scheffer, I.; Gecz, J.; Petrou, S.; Hughes, J.; Thomas, P.

10.1101/178822 — developmental biology — Posted on 2017-08-20

558 WDR88, CCDC11, and ARPP21 genes indulge profoundly in the desmoplastic retort to prostate and breast cancer metastasis.

Jaiswal, R.; Jauhari, S.; Rizvi, S. A. M.

10.1101/178566 — systems biology — Posted on 2017-08-20

559 Inferring propensity amongst lung and breast carcinomas via overlapped gene expression profiles

Jaiswal, R.; Dhakal, S.; Jauhari, S.

10.1101/178558 — systems biology — Posted on 2017-08-20

560 Burden-driven feedback control of gene expression

Ceroni, F.; Furini, S.; Gorochowski, T. E.; Boo, A.; Borkowski, O.; Ladak, Y. N.; Awan, A. R.; Gilbert, C.; Stan, G.-B.; Ellis, T.

10.1101/177030 — synthetic biology — Posted on 2017-08-20

561 Behavioral and neural indices of affective coloring for neutral social stimuli

Grupe, D. W.; Schaefer, S. M.; Lapate, R. C.; Schoen, A. J.; Gresham, L. K.; Mumford, J. A.; Davidson, R. J.

10.1101/178384 — neuroscience — Posted on 2017-08-20

562 Awake fMRI Reveals Mechanisms of Language Comprehension in Dogs

Prichard, A.; Cook, P. F.; Spivak, M.; Chhibber, R.; Berns, G.

10.1101/178186 — neuroscience — Posted on 2017-08-20

563 RNA-dependent intergenerational inheritance of enhanced synaptic plasticity after environmental enrichment

Benito, E.; Kerimoglu, C.; Ramachandran, B.; Zhou, Q.; Pena, T.; Capece, V.; Jain, G.; Burkhardt, S.; Stilling, R.; Edbauer, D.; Dean, C.; Fischer, A.

10.1101/178814 — neuroscience — Posted on 2017-08-20

564 The functional and genetic associations of neuroimaging data: a toolbox

Liu, Z.; Rolls, E. T.; Zhang, J.; Yang, M.; Du, J.; Gong, W.; Cheng, W.; Wang, H.; Ugurbil, K.; Feng, J.

10.1101/178640 — neuroscience — Posted on 2017-08-20

565 Innovations orthogonalization: a solution to the major pitfalls of EEG/MEG "leakage correction"

Pascual-Marqui, R.; Biscay, R. J.; Bosch-Bayard, J.; Faber, P.; Kinoshita, T.; Kochi, K.; Milz, P.; Nishida, K.; Yoshimura, M.

10.1101/178657 — neuroscience — Posted on 2017-08-20

566 Trajectories of Alcohol Use Initiation and Risk to Develop an Alcohol Use Disorder During Adolescence: A Role for Stress and Amygdala Activity

Elsayed, N. M.; Kim, M. J.; Fields, K. M.; Olvera, R. L.; Hariri, A. R.; Williamson, D. E.

10.1101/178251 — neuroscience — Posted on 2017-08-20

567 Enhanced cross-modal activation of sensory cortex in mouse models of autism

Hattori, R.; Südhof, T. C.; Yamakawa, K.; Hensch, T. K.

10.1101/150839 — neuroscience — Posted on 2017-08-20

568 Acute Hepatitis E Virus infection in two geographical regions of Nigeria

Ifeorah, I. M.; Faleye, T. O. C.; Bakarey, A. S.; Adewumi, M. O.; Akere, A.; Omoruyi, C. E.; Ogunwale, A. O.; Adeniji, J. A.

10.1101/178756 — microbiology — Posted on 2017-08-20

569 Development and validation of an expanded carrier screen that optimizes sensitivity via full-exon sequencing and panel-wide copy-number-variant identification

Hogan, G. J.; Vysotskaia, V. S.; Seisenberger, S.; Grauman, P. V.; Beauchamp, K. A.; Haas, K. R.; Hong, S. H.; Jennions, D.; Jeon, D.; Kash, S.; Lai, H. H.; Melroy, L. M.; Theilmann, M. R.; Chu, C. S.; Guha, S.; Iori, K.; Maguire, J. R.; Wong, K. K.; Evans, E. A.; Haque, I. S.; Mar-Heyming, R.; Kang, H. P.; Muzzey, D.

10.1101/178350 — genetics — Posted on 2017-08-20

570 Genes relocated between Drosophila chromosomes evolve under selection pressures different from canonical dispersed duplicates

Hart, M. L. I.; Vu, B. L.; Bolden, Q.; Chen, K. T.; Oakes, C. L.; Zoronjic, L.; Meisel, R.

10.1101/178582 — genetics — Posted on 2017-08-20

571 Evolution of dispersal syndrome and its corresponding metabolomic changes

Tung, S.; Mishra, A.; Gogna, N.; Sadiq, M. A.; Shreenidhi, P. M.; Shree Sruti, V. R.; Dorai, K.; Dey, S.

10.1101/178715 — evolutionary biology — Posted on 2017-08-20

572 Current geography masks dynamic history of gene flow during speciation in northern Australian birds

Penalba, J. V.; Joseph, L.; Moritz, C.

10.1101/178475 — evolutionary biology — Posted on 2017-08-20

573 Adaptation to European latitudes through assimilation of wild diversity at the LuTFL1 locus altered architecture and promoted fiber production in flax.

Gutaker, R.; Zaidem, M.; Fu, Y.-B.; Diederichsen, A.; Smith, O.; Ware, R.; Allaby, R. G.

10.1101/178772 — evolutionary biology — Posted on 2017-08-20

574 Disease mediated changes to life history and demography threaten the survival of European amphibian populations

Campbell, L. J.; Garner, T. W. J.; Tessa, G.; Scheele, B. C.; Wilfert, L.; Griffiths, A. G. F.; Harrison, X. A.

10.1101/178723 — ecology — Posted on 2017-08-20

575 Facilitated analysis of large data sets by interactive visualisation

Lu, Z.; Zhang, Y.

10.1101/178616 — bioinformatics — Posted on 2017-08-20

576 ActiveDriverDB: human disease mutations and genome variation in post-translational modification sites of proteins

Krassowski, M.; Paczkowska, M.; Cullion, K.; Huang, T.; Dzneladze, I.; Ouellette, F.; Yamada, J. T.; Fradet-Turcotte, A.; Reimand, J.

10.1101/178392 — bioinformatics — Posted on 2017-08-20

577 DrugPattern: a web-based tool for drug set enrichment analysis

Huang, C.; Yang, W.; Wang, J.; Zhou, Y.; Geng, B.; Kararigas, G.; Yang, J.; Cui, Q.

10.1101/178632 — bioinformatics — Posted on 2017-08-20

578 Accurate typing of class I human leukocyte antigen by Oxford nanopore sequencing

Liu, C.; Xiao, F.; Hoisington-Lopez, J.; Lang, K.; Quenzel, P.; Duffy, B.; Mitra, R. D.

10.1101/178590 — bioinformatics — Posted on 2017-08-20

579 Targeting individual cells by barcode in pooled sequence libraries

Ranu, N.; Villani, A.-C.; Hacohen, N.; Blainey, P. C.

10.1101/178681 — bioengineering — Posted on 2017-08-20

580 Widespread utilization of passive energy recapture in swimming medusae

Gemmell, B. J.; Colin, S. P.; Costello, J. H.

10.1101/178467 — animal behavior and cognition — Posted on 2017-08-20

581 Understanding The Dynamics Of Laboratory Populations Of Drosophila melanogaster: Long-Term Experiments Meet Individual-Based Modelling

Tung, S.; Rajamani, M.; Joshi, A.; Dey, S.

10.1101/138446 — ecology — Posted on 2017-08-20

582 Cyclin G And The Polycomb Repressive Complexes PRC1 And PR-DUB Cooperate For Developmental Stability

Dardalhon-Cumenal, D.; Deraze, J.; Dupont, C. A.; Ribeiro, V.; Coleno-Costes, A.; Pouch, J.; Le Crom, S.; Thomassin-Bourrel, H.; Debat, V.; Randsholt, N. B.; Peronnet, F.

10.1101/144048 — developmental biology — Posted on 2017-08-20

583 Pivot-and-bond model explains microtubule bundle formation

Prelogovic, M.; Winters, L.; Milas, A.; Tolic, I.; Pavin, N.

10.1101/157719 — biophysics — Posted on 2017-08-20

584 Intrinsic functional connectivity of the central extended amygdala

Tillman, R. M.; Stockbridge, M. D.; Nacewicz, B. M.; Torrisi, S.; Fox, A. S.; Smith, J. F.; Shackman, A. J.

10.1101/178533 — neuroscience — Posted on 2017-08-20

585 Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens

Amberg-Johnson, K.; Hari, S. B.; Ganesan, S. M.; Lorenzi, H. A.; Sauer, R. T.; Niles, J. C.; Yeh, E.

10.1101/108910 — microbiology — Posted on 2017-08-19

586 Bimodal Spindle Orientation Drives Tissue Regularity in a Proliferating Epithelium

Finegan, T. M.; Na, D.; Skeeters, A. V.; Dawney, N. S.; Oakes, P. W.; Fletcher, A.; Bergstralh, D. T.

10.1101/178517 — developmental biology — Posted on 2017-08-19

587 NMR studies reveal that protein dynamics critically mediate aggregation of the well-folded and very soluble E. coli S1 ribosomal protein

Lu, Y.; Lim, L.; Song, J.

10.1101/178459 — biophysics — Posted on 2017-08-19

588 The Effects Of Oncogenic G12D Mutation On K-Ras Structure, Conformation And Dynamics

Vatansever, S.; Gumus, Z.; Erman, B.

10.1101/178483 — biophysics — Posted on 2017-08-19

589 A Multi-Parameter Analysis of Cellular Coordination of Major Transcriptome Regulation Mechanisms

Jiang, W.; Guo, Z.; Lages, N.; Zheng, W. J.; Feliers, D.; Zhang, F.; Wang, D.

10.1101/104901 — systems biology — Posted on 2017-08-19

590 Community-based benchmarking improves spike inference from two-photon calcium imaging data

Berens, P.; Freeman, J.; Deneux, T.; Chenkov, N.; McColgan, T.; Speiser, A.; Macke, J. H.; Turaga, S.; Mineault, P.; Rupprecht, P.; Gerhard, S.; Friedrich, R. W.; Friedrich, J.; Paninski, L.; Pachitariu, M.; Harris, K. D.; Bolte, B.; Machado, T. A.; Ringach, D.; Stone, J.; Sofroniew, N. J.; Reimer, J.; Froudarakis, E.; Euler, T.; Roman-Roson, M.; Theis, L.; Tolias, A. S.; Bethge, M.

10.1101/177956 — neuroscience — Posted on 2017-08-19

591 Dominant integration locus drives continuous diversification of plant immune receptors with exogenous domain fusions

Bailey, P. C.; Schudoma, C.; Jackson, W.; Baggs, E.; Dagdas, G.; Haerty, W.; Moscou, M.; Krasileva, K. V.

10.1101/100834 — evolutionary biology — Posted on 2017-08-19

592 Evolution Of Pre-Copulatory And Post-Copulatory Strategies Of Inbreeding Avoidance And Associated Polyandry

Duthie, A. B.; Bocedi, G.; Germain, R. R.; Reid, J. M.

10.1101/136093 — evolutionary biology — Posted on 2017-08-19

593 Toward Capturing the Exposome: Exposure Biomarker Variability and Co-Exposure Patterns in the Shared Environment

Chung, M. K.; Kannan, K.; Louis, G. M. B.; Patel, C. J.

10.1101/175513 — epidemiology — Posted on 2017-08-19

594 Acquisition of cell migration defines NK cell differentiation from hematopoietic stem cell precursors

Lee, B. J.; Mace, E. M.

10.1101/142380 — cell biology — Posted on 2017-08-19

595 Widespread impact of DNA replication on mutational mechanisms in cancer

Tomkova, M.; Tomek, J.; Kriaucionis, S.; Schuster-Boeckler, B.

10.1101/111302 — cancer biology — Posted on 2017-08-19

596 Distributed cortical structural properties contribute to motor cortical excitability and inhibition

Dayan, E.; Lopez-Alonso, V.; Liew, S.-L.; Cohen, L.

10.1101/178301 — neuroscience — Posted on 2017-08-19

597 The effect of sonic hedgehog on motor neuron positioning in the spinal cord during chicken embryo development

Yang, C.; Li, X.; Li, Q.; Li, Q.; Li, H.; Zhang, B.; Lin, J.

10.1101/178491 — developmental biology — Posted on 2017-08-19

598 L(3)mbt safeguards tissue identity by maintaining transcriptional integrity at head-to-head genes

Coux, R.-X.; Karam Teixeira, F.; Lehmann, R.

10.1101/178194 — developmental biology — Posted on 2017-08-19

599 Detection of domain motion in NADPH-cytochrome P450 oxidoreductase through polarization anisotropy measurements

Kovrigina, E. A.; Xia, C.; Kim, J.-J.; Kovrigin, E. L.

10.1101/178426 — biochemistry — Posted on 2017-08-19

600 Labeling of prokaryotic mRNA in live cells using fluorescent in situ hybridization of transcript-annealing molecular beacons (FISH-TAMB)

Harris, R.; Lau, M. C. Y.; van Heerden, E.; Cason, E.; Vermeulen, J.-G.; Taneja, A.; Kieft, T. L.; DeCoste, C.; Laevsky, G.; Onstott, T. C.

10.1101/178368 — microbiology — Posted on 2017-08-19

601 A minimal RNA ligand for potent RIG-I activation in living mice

Linehan, M. M.; Dickey, T. H.; Molinari, E. S.; Fitzgerald, M. E.; Potapova, O.; Iwasaki, A.; Pyle, A. M.

10.1101/178343 — immunology — Posted on 2017-08-19

602 Deep learning: Using machine learning to study biological vision

Majaj, N. J.; Pelli, D. G.

10.1101/178152 — neuroscience — Posted on 2017-08-18

603 Mapping movement, mood, motivation, and mentation in the subthalamic nucleus

Gourisankar, A.; Eisenstein, S. A.; Trapp, N. T.; Koller, J. M.; Campbell, M. C.; Ushe, M.; Perlmutter, J. S.; Hershey, T.; Black, K. J.

10.1101/168302 — neuroscience — Posted on 2017-08-18

604 Extraordinary Self-Sacrifice

Krupp, D. B.

10.1101/178376 — evolutionary biology — Posted on 2017-08-18

605 Deeper sequencing at unexpected CRISPR/Cas9 off-target sites in vivo : A response to Editas, Intellia, Beacon, ToolGen and others

Schaefer, K. A.; Wu, W.-H.; Darbro, B. W.; Colgan, D. F.; Tsang, S. H.; Bassuk, A. G.; Mahajan, V. B.

10.1101/154450 — bioengineering — Posted on 2017-08-18

606 A dual-mode mobile phone microscope using the onboard camera flash and ambient light

Orth, A.; Wilson, E. R.; Thompson, J.; Gibson, B. C.

10.1101/162008 — bioengineering — Posted on 2017-08-18

607 Pathogen-Host Analysis Tool (PHAT): an Integrative Platform to Analyze Pathogen-Host Relationships in Next-Generation Sequencing Data

Gibb, C. M.; Jackson, R.; Mohammed, S.; Fiaidhi, J.; Zehbe, I.

10.1101/178327 — bioinformatics — Posted on 2017-08-18

608 Cadmium Exposure Increases The Risk Of Juvenile Obesity: A Human And Zebrafish Comparative Study

Green, A. J.; Hoyo, C.; Mattingly, C. J.; Luo, Y.; Tzeng, J.-Y.; Murphy, S.; Planchart, A.

10.1101/172346 — epidemiology — Posted on 2017-08-18

609 Resources For Interpreting Variants In Precision Genomic Oncology Applications

Tsang, H.; Addepalli, K.; Davis, S. R.

10.1101/144766 — bioinformatics — Posted on 2017-08-18

610 Regulatory divergence of flowering time genes in the allopolyploid Brassica napus

Jones, M.; Pullen, N.; Wells, R.; Trick, M.; Irwin, J.; Morris, R.

10.1101/178137 — plant biology — Posted on 2017-08-18

611 The Anti-Epileptic Ketogenic Diet Alters Hippocampal Transporter Levels and Reduces Adiposity in Aged Rats

Hernandez, A. R.; Hernandez, C. M.; Campos, K.; Truckenbrod, L. M.; Sakarya, Y.; McQuail, J. A.; Carter, C. S.; Bizon, J. L.; Maurer, A. P.; Burke, S. N.

10.1101/178319 — neuroscience — Posted on 2017-08-18

612 CTCF, WAPL and PDS5 proteins control the formation of TADs and loops by cohesin

Wutz, G.; Varnai, C.; Nagasaka, K.; Cisneros, D. A.; Stocsits, R.; Tang, W.; Schoenfelder, S.; Jessberger, G.; Muhar, M.; Hossain, J. M.; Walther, N.; Koch, B.; Kueblbeck, M.; Ellenberg, J.; Zuber, J.; Fraser, P.; Peters, J.-M.

10.1101/177444 — genomics — Posted on 2017-08-18

613 Genomic prediction reveals significant non-additive effects for growth in hybrid Eucalyptus

Tan, B.; Grattapaglia, D.; Wu, H. X.; Ingvarsson, P. K.

10.1101/178160 — genetics — Posted on 2017-08-18

614 Phenotypes associated with female X chromosome aneuploidy in UK Biobank: an unselected, adult, population-based cohort

Tuke, M. A.; Ruth, K. S.; Wood, A. R.; Beaumont, R. N.; Tyrrell, J.; Jones, S. E.; Yaghootkar, H.; Turner, C. L. S.; Donohoe, M. E.; Brooke, A. M.; Collinson, M. N.; Freathy, R. M.; Weedon, M. N.; Frayling, T. M.; Murray, A.

10.1101/177659 — genetics — Posted on 2017-08-18

615 Lhr and Hmr are required for sister chromatid detachment during anaphase but not for centromere function

Blum, J. A.; Bonaccorsi, S.; Marzullo, M.; Palumbo, V.; Yamashita, Y.; Barbash, D.; Gatti, M.

10.1101/178046 — genetics — Posted on 2017-08-18

616 Biofilm formation and toxin production provide a fitness advantage in mixed colonies of natural yeast isolates

Deschaine, B. M.; Heysel, A. R.; Lenhart, B. A.; Murphy, H.

10.1101/178244 — evolutionary biology — Posted on 2017-08-18

617 Systemic HIV-1 Infection Produces a Unique Glial Footprint in Humanized Mouse Brains

Li, W.; Gorantla, S.; Gendelman, H. E.; Poluektova, L.

10.1101/178285 — neuroscience — Posted on 2017-08-18

618 Modeling of dynamic cerebrovascular reactivity to spontaneous and externally induced CO2 fluctuations in the human brain using BOLD-fMRI

Prokopiou, P. C.; Pattinson, K. T. S.; Wise, R. G.; Mitsis, G. D.

10.1101/176891 — neuroscience — Posted on 2017-08-18

619 Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

Davies, G.; Lam, M.; Harris, S. E.; Trampush, J.; Luciano, M.; Hill, W. D.; Hagenaars, S. P.; Ritchie, S. J.; Marioni, R. E.; Fawns-Ritchie, C.; Liewald, D. C.; Okely, J.; Ahola-Olli, A.; Barnes, C. L. K.; Bertram, L.; Bis, J. C.; Burdick, K. E.; Christoforou, A.; DeRosse, P.; Djurovic, S.; Espeseth, T.; Giakoumaki, S.; Giddaluru, S.; Gustavson, D. E.; Hayward, C.; Hofer, E.; Ikram, M. A.; Karlsson, R.; Knowles, E.; Lahti, J.; Leber, M.; Li, S.; Mather, K. A.; Melle, I.; Morris, D.; Oldmeadow, C.; Palviainen, T.; Payton, A.; Pazoki, R.; Petrovic, K.; Reynolds, C. A.; Sargurupremraj, M.; Scholz

10.1101/176511 — genetics — Posted on 2017-08-18

620 Machine learning analysis identifies Drosophila Grunge/Atrophin as an important learning and memory gene required for memory retention and social learning.

Kacsoh, B. Z.; Greene, C.; Bosco, G.

10.1101/157610 — genetics — Posted on 2017-08-18

621 Quartet Sampling distinguishes lack of support from conflicting support in the plant tree of life

Pease, J. B.; Brown, J. W.; Walker, J. F.; Hinchliff, C. E.; Smith, S. A.

10.1101/148536 — evolutionary biology — Posted on 2017-08-18

622 Abundance-based reconstitution of microbial pan-genomes from whole-metagenome shotgun sequencing data

Plaza Onate, F.; Cervino, A. C. L.; Magoules, F.; Ehrlich, S. D.; Pichaud, M.

10.1101/173203 — bioinformatics — Posted on 2017-08-18

623 Comparative analyses of toxin-associated gene homologs from an Old World viper, Daboia russelii.

Krishnan, N. M.; Panda, B.

10.1101/152082 — bioinformatics — Posted on 2017-08-18

624 Deeper sequencing at unexpected CRISPR/Cas9 off-target sites in vivo : A response to Editas, Intellia, Beacon, ToolGen and others

Schaefer, K. A.; Wu, W.-H.; Darbro, B. W.; Colgan, D. F.; Tsang, S. H.; Bassuk, A. G.; Mahajan, V. B.

10.1101/154450 — bioengineering — Posted on 2017-08-18

625 Human occipital bone sexual dimorphism in an Archiac period archaeological population

Hoover, K. C.

10.1101/177758 — physiology — Posted on 2017-08-18

626 Withdrawal-induced escalated oxycodone self-administration is mediated by kappa opioid receptor function

Nguyen, J. D.; Kirson, D.; Steinman, M. Q.; Patel, R.; Khom, S.; Varodayan, F. P.; Hedges, D. M.; Oleata, C. S.; Grant, Y.; Roberto, M.; Taffe, M. A.

10.1101/177899 — neuroscience — Posted on 2017-08-18

627 Oxytocin Signaling in the Medial Amygdala is required for Sex Discrimination of Social Cues

Yao, S.; Bergan, J.; Lanjuin, A.; Dulac, C.

10.1101/178210 — neuroscience — Posted on 2017-08-18

628 Predictive coding over the lifespan: Increased reliance on perceptual priors in older adults -- a magnetoencephalography and dynamic causal modelling study

Chan, J. S.; Wibral, M.; Wollstadt, P.; Stawowsky, C.; Brandl, M.; Helbling, S.; Naumer, M.; Kaiser, J.

10.1101/178095 — neuroscience — Posted on 2017-08-18

629 Translated Blast of L Polymerase as a Hit for Novel Arenaviruses Species

Alrashedi, H. S.; Jones, I.; Mulley, G.; Neuman, B.

10.1101/178012 — microbiology — Posted on 2017-08-18

630 A gut pathobiont synergizes with the microbiota to instigate inflammatory disease marked by immunoreactivity against other symbionts but not itself

Gomes-Neto, J. C.; Kittana, H.; Mantz, S.; Segura Munoz, R. R.; Schmaltz, R. J.; Bindels, L. B.; Clarke, J.; Hostetter, J. M.; Benson, A. K.; Walter, J.; Ramer-Tait, A. E.

10.1101/178038 — immunology — Posted on 2017-08-18

631 Pathways analyses of schizophrenia GWAS focusing on known and novel drug targets

Gaspar, H. A.; Breen, G.

10.1101/091264 — genomics — Posted on 2017-08-18

632 Evolutionary history of New World monkeys revealed by molecular and fossil data

Silvestro, D.; Tejedor, M. F.; Serrano-Serrano, M. L.; Loiseau, O.; Rossier, V.; Rolland, J.; Zizka, A.; Antonelli, A.; Salamin, N.

10.1101/178111 — evolutionary biology — Posted on 2017-08-18

633 SFMetaDB: A Comprehensive Annotation of Mouse RNA Splicing Factor RNA-Seq Datasets

Li, J.; Tseng, C.-S.; Federico, A.; Ivankovic, F.; Huang, Y.-S.; Ciccodicola, A.; Swanson, M. S.; Yu, P.

10.1101/177931 — bioinformatics — Posted on 2017-08-18

634 CHIC: a short read aligner for pan-genomic references

Valenzuela, D.; Mäkinen, V.

10.1101/178129 — bioinformatics — Posted on 2017-08-18

635 Building a genome browser with GIVE

Cao, X.; Zheng, A.; Zhong, S.

10.1101/177832 — bioinformatics — Posted on 2017-08-18

636 CarrierSeq: a sequence analysis workflow for low-input nanopore sequencing

Mojarro, A.; Hachey, J.; Ruvkun, G.; Zuber, M. T.; Carr, C. E.

10.1101/175281 — bioinformatics — Posted on 2017-08-18

637 npInv: accurate detection and genotyping of inversions mediated by non-allelic homologous recombination using long read sub-alignment

Shao, H.; Ganesamoorthy, D.; Duarte, T.; Cao, M. D.; Hoggart, C.; Coin, L.

10.1101/178103 — bioinformatics — Posted on 2017-08-18

638 Uniform Resolution of Compact Identifiers for Biomedical Data

Wimalaratne, S.; Juty, N.; Kunze, J.; Janee, G.; McMurry, J. A.; Beard, N.; Jimenez, R.; Grethe, J.; Hermjakob, H.; Clark, T.

10.1101/101279 — bioinformatics — Posted on 2017-08-18

639 RNA editing of CAPS1 regulates synaptic vesicle organization, release and retrieval.

Ulbricht, R. J.; Sun, S. J.; DelBove, C. E.; Kitko, K. E.; Rehman, S. C.; Wang, M. Y.; Lazarenko, R. M.; Zhang, Q.; Emeson, R.

10.1101/178202 — biochemistry — Posted on 2017-08-18

640 microRNA tissue atlas of the malaria mosquito Anopheles gambiae

Lampe, L.; Levashina, E. A.

10.1101/177964 — genomics — Posted on 2017-08-18

641 Frequent paramutation-like features of natural epialleles in tomato

Gouil, Q.; Baulcombe, D.

10.1101/177972 — genomics — Posted on 2017-08-18

642 Map-based cloning of the gene Pm21 that confers broad spectrum resistance to wheat powdery mildew

He, H.; Zhu, S.; Ji, Y.; Jiang, Z.; Zhao, R.; Bie, T.

10.1101/177857 — genetics — Posted on 2017-08-18

643 The RS Domain of Human CFIm68 Plays a Key Role in Selection Between Alternative Sites of Pre-mRNA Cleavage and Polyadenylation

Hardy, J. G.; Tellier, M.; Murphy, S.; Norbury, C. J.

10.1101/177980 — molecular biology — Posted on 2017-08-18

644 Characterizing a thermostable Cas9 for bacterial genome editing and silencing

Mougiakos, I.; Mohanraju, P.; Bosma, E. F.; Vrouwe, V.; Finger Bou, M.; Naduthodi, M. I. S.; Gussak, A.; Brinkman, R. B. L.; van Kranenburg, R.; van der Oost, J.

10.1101/177717 — microbiology — Posted on 2017-08-18

645 SPIN1 promotes tumorigenesis by blocking the uL18-MDM2-p53 pathway

Fang, Z.; Liao, J.-M.; Cao, B.; Deng, J.; Plummer, K. D.; Liao, P.; Liu, T.; Zeng, S. X.; Xiong, J.; Lu, H.

10.1101/177881 — cancer biology — Posted on 2017-08-18

646 Feed-forward and Feedback Control in Astrocytes for Ca2+-based Molecular Communications Nanonetworks

Barros, M. T.; Dey, S.

10.1101/177154 — neuroscience — Posted on 2017-08-18

647 Community-based benchmarking improves spike inference from two-photon calcium imaging data

Berens, P.; Freeman, J.; Deneux, T.; Chenkov, N.; McColgan, T.; Speiser, A.; Macke, J. H.; Turaga, S.; Mineault, P.; Rupprecht, P.; Gerhard, S.; Friedrich, R. W.; Friedrich, J.; Paninski, L.; Pachitariu, M.; Harris, K. D.; Bolte, B.; Machado, T. A.; Ringach, D.; Reimer, J.; Froudarakis, E.; Euler, T.; Roman-Roson, M.; Theis, L.; Tolias, A. S.; Bethge, M.

10.1101/177956 — neuroscience — Posted on 2017-08-18

648 The small non-coding vault RNA1-1 acts as a riboregulator of autophagy

Horos, R.; Alleaume, A.-M.; Kleinendorst, R.; Tarafder, A. K.; Schwarzl, T.; Zielonka, E. M.; Adak, A.; Castello, A.; Huber, W.; Sachse, C.; Hentze, M. W.

10.1101/177949 — molecular biology — Posted on 2017-08-18

649 Use of whole genome sequencing to investigate an outbreak of gonorrhoea among females in urban New South Wales, Australia, 2012 to 2014.

Buckley, C.; Forde, B.; Trembizki, E.; Lahra, M.; Beatson, S.; Whiley, D.

10.1101/175869 — epidemiology — Posted on 2017-08-18

650 Toward Capturing the Exposome: Exposure Biomarker Variability and Co-Exposure Patterns in the Shared Environment

Chung, M. K.; Kannan, K.; Louis, G. M. B.; Patel, C. J.

10.1101/175513 — epidemiology — Posted on 2017-08-18

651 Expression of lamina proteins Lamin Dm0 and Kugelkern suppresses stem cell proliferation

Petrovsky, R.; Grosshans, J.

10.1101/177998 — developmental biology — Posted on 2017-08-18

652 Decoupling the roles of cell shape and mechanical stress in orienting and cueing epithelial mitosis

Nestor-Bergmann, A.; Stooke-Vaughan, G. A.; Goddard, G. K.; Starborg, T.; Jensen, O. E.; Woolner, S.

10.1101/177592 — cell biology — Posted on 2017-08-18

653 Precise, pan-cancer discovery of gene fusions reveals a signature of selection in primary tumors

Freeman, D. E.; Hsieh, G. L.; Howard, J. M.; Lehnert, E. M.; Salzman, J.

10.1101/178061 — cancer biology — Posted on 2017-08-18

654 LIM Protein Ajuba associates with the RPA complex through direct and cell cycle-dependent interaction with the RPA70 subunit.

Fowler, S.; Maguin, P.; Kalan, S.; Loayza, D.

10.1101/177840 — cancer biology — Posted on 2017-08-18

655 BCL-3 enhances β-catenin signalling in colorectal tumour cells promoting a cancer stem cell phenotype

Legge, D. N.; Shephard, A. P.; Collard, T. J.; Greenhough, A.; Chambers, A. C.; Clarkson, R. W.; Paraskeva, C.; Williams, A. C.

10.1101/178004 — cancer biology — Posted on 2017-08-18

656 Specific excitatory connectivity for feature integration in mouse primary visual cortex

Muir, D.; Molina-Luna, P.; Roth, M. M.; Helmchen, F.; Kampa, B.

10.1101/072595 — neuroscience — Posted on 2017-08-18

657 Inhibition of NHEJ repair by type II-A CRISPR-Cas systems

Bernheim, A.; Calvo Villamanan, A.; Basier, C.; Rocha, E. P. C.; Touchon, M.; Bikard, D.

10.1101/170647 — microbiology — Posted on 2017-08-18

658 An atlas of genetic associations in UK Biobank

Canela-Xandri, O.; Rawlik, K.; Tenesa, A.

10.1101/176834 — genetics — Posted on 2017-08-18

659 An Eigenvalue Test for spatial Principal Component Analysis

Montano, V.; Jombart, T.

10.1101/151639 — evolutionary biology — Posted on 2017-08-18

660 Stacked Generalization: An Introduction to Super Learning

Naimi, A.; Balzer, L. B.

10.1101/172395 — epidemiology — Posted on 2017-08-18

661 Assessing the performance of real-time epidemic forecasts

Funk, S.; Camacho, A.; Kucharski, A. J.; Lowe, R.; Eggo, R. M.; Edmunds, W. J.

10.1101/177451 — epidemiology — Posted on 2017-08-18

662 Euplotid: A Linux-based platform to physically edit the genome

Borges-Rivera, D.

10.1101/170159 — biophysics — Posted on 2017-08-18

663 Integrative analysis of large scale transcriptome data draws a comprehensive functional landscape of Phaeodactylum tricornutum genome and evolutionary origin of diatoms

Rastogi, A.; Maheswari, U.; Dorrell, R. G.; Maumus, F.; Rocha Jimenez Vieira, F.; Kustka, A.; McCarthy, J.; Allen, A. E.; Kersey, P.; Bowler, C.; Tirichine, L.

10.1101/176024 — bioinformatics — Posted on 2017-08-18

664 Dynamics of corticospinal motor control during overground and treadmill walking in humans

Roeder, L.; Boonstra, T. W.; Kerr, G. K.

10.1101/177915 — physiology — Posted on 2017-08-18

665 Ligand-regulated entry into the HRD ERAD pathway: The dark side of allostery

Wangeline, M. A.; Hampton, R. Y.

10.1101/177311 — cell biology — Posted on 2017-08-18

666 GIC: A computational method for predicting the essentiality of long noncoding lncRNAs

Zeng, P.; Chen, J.; Zhou, Y.; Yang, J.; Cui, Q.

10.1101/177923 — bioinformatics — Posted on 2017-08-18

667 Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity

Lee, Y.; Nishizawa, T.; Takemoto, M.; Kumazaki, K.; Yamashita, K.; Hirata, K.; Minoda, A.; Nagatoishi, S.; Tsumoto, K.; Ishitani, R.; Nureki, O.

10.1101/169169 — biochemistry — Posted on 2017-08-18

668 Comparing colours using visual models

Maia, R.; White, T.

10.1101/175992 — animal behavior and cognition — Posted on 2017-08-18

669 A genome resequencing-based genetic map reveals the recombination landscape of an outbred parasitic nematode in the presence of polyploidy and polyandry

Doyle, S. R.; Laing, R.; Bartley, D. J.; Britton, C.; Chaudhry, U.; Gilleard, J. D.; Holroyd, N.; Mable, B. K.; Maitland, K.; Morrison, A. A.; Tait, A.; Tracey, A.; Berriman, M.; Devaney, E.; Cotton, J. A.; Sargison, N. D.

10.1101/177550 — genomics — Posted on 2017-08-17

670 De novo organelle biogenesis in the cyanobacterium TDX16 released from the green alga Haematococcus pluvialis

Dong, Q.-l.; Xing, X.-y.; Han, Y.; Wei, X.-l.; Zhang, S.

10.1101/161463 — cell biology — Posted on 2017-08-17

671 Replication of early and recent Zika virus isolates throughout mouse brain development

Rosenfeld, A. B.; Doobin, D. J.; Warren, A. L.; Racaniello, V. R.; Vallee, R. B.

10.1101/177816 — microbiology — Posted on 2017-08-17

672 Case report: intermittent fasting and probiotic yogurt consumption are associated with reduction of serum alpha-N-acetylgalactosaminidase and increased urinary excretion of lipophilic toxicants

Blythe, J.; Pacini, S.

10.1101/177774 — pharmacology and toxicology — Posted on 2017-08-17

673 Modeling of dynamic cerebrovascular reactivity to spontaneous and externally induced CO2 fluctuations in the brainstem respiratory control centers in the human brain using BOLD-fMRI

Prokopiou, P. C.; Pattinson, K. T. S.; Wise, R. G.; Mitsis, G. D.

10.1101/176891 — neuroscience — Posted on 2017-08-17

674 Characteristics of a Block to Entry via an HIV-2 Envelope, MCR

Gray, E. R.

10.1101/177808 — microbiology — Posted on 2017-08-17

675 The effect of Wnt signaling on the localization, molecular size and activity of the beta-catenin destruction complex in vivo

Schaefer, K.; Zhang, S.; Bonello, T.; Williams, C.; McKay, D.; Peifer, M.

10.1101/177790 — developmental biology — Posted on 2017-08-17

676 A non-catalytic role of TET3 promotes open chromatin and enhances global transcription

Krueger, C.; Peat, J. R.; Eckersley-Maslin, M. A.; Hore, T. A.; Mohammed, H.; Andrews, S. R.; Dean, W.; Reik, W.

10.1101/177626 — developmental biology — Posted on 2017-08-17

677 The evolution of thermoregulatory nesting behaviour in Peromyscus mice

Lewarch, C. L.; Hoekstra, H. E.

10.1101/177782 — animal behavior and cognition — Posted on 2017-08-17

678 Replication defective viral genomes exploit a cellular pro-survival mechanism to establish paramyxovirus persistence

Xu, J.; Sun, Y.; Li, Y.; Ruthel, G.; Weiss, S. R.; Raj, A.; Beiting, D.; Lopez, C. B.

10.1101/120766 — microbiology — Posted on 2017-08-17

679 A Mechanism of Cohesin-Dependent Loop Extrusion Organizes Zygotic Genome Architecture

Gassler, J.; Brandao, H. B.; Imakaev, M.; Flyamer, I. M.; Ladstatter, S.; Bickmore, W. A.; Peters, J.-M.; Mirny, L. A.; Tachibana-Konwalski, K.

10.1101/177766 — genomics — Posted on 2017-08-17

680 CTCF, WAPL and PDS5 proteins control the formation of TADs and loops by cohesin

10.1101/177444 — genomics — Posted on 2017-08-17

681 A framework for estimating the determinants of spatial and temporal variation in vital rates and inferring the occurrence of unobserved extreme events

Vincenzi, S.; Jesensek, D.; Crivelli, A. J.

10.1101/033720 — ecology — Posted on 2017-08-17

682 Investigating the existence of periodicity in activity of neural network by novel neural signal processing technique - quantifying induced learning in cell culture

Biswas, S.

10.1101/177360 — systems biology — Posted on 2017-08-17

683 Feed-forward and Feedback Control in Astrocytes for Ca2+-based Molecular Communications Nanonetworks

Barros, M. T.; Dey, S.

10.1101/177154 — neuroscience — Posted on 2017-08-17

684 A high-performance, inexpensive setup for simultaneous multi-site recording of electrophysiological signals and wide-field optical imaging of the mouse cortex

Bermudez Contreras, E. J.; Chekhov, S.; Tarnowsky, J.; Sun, J.; McNaughton, B. L.; Mohajerani, M. H.

10.1101/177188 — neuroscience — Posted on 2017-08-17

685 Simulating Extracted Connectomes

Gornet, J.; Scheffer, L. K.

10.1101/177113 — neuroscience — Posted on 2017-08-17

686 Thiol-linked alkylation for the metabolic sequencing of RNA

Herzog, V. A.; Reichholf, B.; Neumann, T.; Rescheneder, P.; Bhat, P.; Burkard, T. R.; Wlotzka, W.; von Haeseler, A.; Zuber, J.; Ameres, S. L.

10.1101/177642 — molecular biology — Posted on 2017-08-17

687 Assortative mating on ancestry-variant traits in admixed Latin American populations

Norris, E. T.; Rishishwar, L.; Wang, L.; Conley, A. B.; Chande, A. T.; Dabrowski, A. M.; Valderrama-Aguirre, A.; Jordan, I. K.

10.1101/177634 — genomics — Posted on 2017-08-17

688 On the Stability Landscape of the Human Gut Microbiome: Implications for Microbiome-based Therapies

Gibson, T. E.; Carey, V.; Bashan, A.; Hohmann, E. L.; Weiss, S. T.; Liu, Y.-Y.

10.1101/176941 — ecology — Posted on 2017-08-17

689 Effects of species invasion on population dynamics, vital rates, and life histories of the native species

Vincenzi, S.; Crivelli, A. J.; Jesensek, D.; Campbell, E.; Garza, J. C.

10.1101/177741 — ecology — Posted on 2017-08-17

690 Stronger effects of heterozygosity on survival in harsherenvironments

Vincenzi, S.; Jesensek, D.; Garza, J. C.; Crivelli, A. J.

10.1101/177725 — ecology — Posted on 2017-08-17

691 Dynamic, non-contact 3D sample rotation for microscopy

Berndt, F.; Shah, G.; Brugues, J.; Huisken, J.

10.1101/177733 — bioengineering — Posted on 2017-08-17

692 Stereotyped p53 binding tuned by chromatin accessibility

Hafner, A.; Lahav, G.; Stewart-Ornstein, J.

10.1101/177667 — genomics — Posted on 2017-08-17

693 TCGAbiolinksGUI: A graphical user interface to analyze GDC cancer molecular and clinical data

Silva, T. C.; Colaprico, A.; Olsen, C.; Bontempi, G.; Ceccarelli, M.; Berman, B. P.; Noushmehr, H.

10.1101/147496 — bioinformatics — Posted on 2017-08-17

694 Substrate sequence selectivity of APOBEC3A implicates intra-DNA interactions

Silvas, T. V.; Hou, S.; Myint, W.; Somasundaran, M.; Kelch, B. A.; Matsuo, H.; Kurt Yilmaz, N.; Schiffer, C. A.

10.1101/176297 — biochemistry — Posted on 2017-08-17

695 On the bioconversion of dietary carotenoids to astaxanthin and its distribution in the marine copepod, Tigriopus californicus

Weaver, R. J.; Cobine, P. A.; Hill, G. E.

10.1101/174300 — zoology — Posted on 2017-08-17

696 Transient Reduction of DNA Methylation at the Onset of Meiosis in Male Mice

Gaysinskaya, V.; Miller, B. F.; van der Heijden, G. W.; Hansen, K. D.; Bortvin, A.

10.1101/177535 — molecular biology — Posted on 2017-08-17

697 Mechanisms of surface antigenic variation in the human pathogenic fungus Pneumocystis jirovecii

Schmid-Siegert, E.; Richard, S.; Luraschi, A.; Muehlethaler, K.; Pagni, M.; Hauser, P.

10.1101/158881 — microbiology — Posted on 2017-08-17

698 De novo mutations involved in post-transcriptional dysregulation contribute to six neuropsychiatric disorders

Mao, F.; Wang, L.; Liu, Q.; Li, X.; Xiao, L.; He, X.; Rao, R. C.; Li, J.; Dou, Y.; Sun, Z.

10.1101/175844 — genomics — Posted on 2017-08-17

699 Frequent lack of repressive capacity of promoter DNA methylation identified through genome-wide epigenomic manipulation

Ford, E. E.; Grimmer, M. R.; Stolzenburg, S.; Bogdanovic, O.; de Mendoza, A.; Farnham, P. J.; Blancafort, P.; Lister, R.

10.1101/170506 — genomics — Posted on 2017-08-17

700 Pivot-and-bond model explains microtubule bundle formation

Prelogovic, M.; Winters, L.; Milas, A.; Tolic, I.; Pavin, N.

10.1101/157719 — biophysics — Posted on 2017-08-17

701 Abundance-based reconstitution of microbial pan-genomes from whole-metagenome shotgun sequencing data

Plaza Onate, F.; Cervino, A. C. L.; Magoules, F.; Ehrlich, S. D.; Pichaud, M.

10.1101/173203 — bioinformatics — Posted on 2017-08-17

702 PBxplore: A Tool To Analyze Local Protein Structure And Deformability With Protein Blocks

Barnoud, J.; Santuz, H.; Craveur, P.; Joseph, A. P.; Jallu, V.; de Brevern, A. G.; Poulain, P.

10.1101/136408 — bioinformatics — Posted on 2017-08-17

703 Saccharomyces cerevisiae as a platform for assessing sphingolipid kinase inhibitors

Kharel, Y.; Agah, S.; Huang, T.; Mendelson, A. J.; Barkey-Bircann, P.; Eletu, O. T.; Gesualdi, J.; Smith, J. S.; Santos, W. L.; Lynch, K. R.

10.1101/148858 — biochemistry — Posted on 2017-08-17

704 Molecular characterization of latent GDF8 reveals mechanisms of activation

Walker, R. G.; McCoy, J. C.; Czepnik, M.; Mills, M. J.; Hagg, A.; Walton, K. L.; Cotton, T.; Hyvonen, M.; Lee, R. T.; Gregorevic, P.; Harrison, C. A.; Thompson, T.

10.1101/155614 — biochemistry — Posted on 2017-08-17

705 Estimated costs of implementing an open access policy at a private foundation

Strasser, C.; Khare, E.

10.1101/128413 — scientific communication and education — Posted on 2017-08-17

706 Biophysical modeling of neural plasticity induced by transcranial magnetic stimulation

Wilson, M. T.; Fulcher, B. D.; Fung, P. K.; Robinson, P. A.; Fornito, A.; Rogasch, N. C.

10.1101/175893 — neuroscience — Posted on 2017-08-17

707 Computational mechanisms underlying cortical responses to the affordance properties of visual scenes

Bonner, M. F.; Epstein, R. A.

10.1101/177329 — neuroscience — Posted on 2017-08-17

708 Profiling RNA-Seq at multiple resolutions markedly increases the number of causal eQTLs in autoimmune disease

Odhams, C. A.; Cunninghame Graham, D. S.; Vyse, T. J.

10.1101/128728 — genetics — Posted on 2017-08-17

709 Yeast de novo genes preferentially emerge from divergently transcribed, GC-rich intergenic regions

Vakirlis, N.; Hebert, A. S.; Opulente, D. A.; Achaz, G.; Hittinger, C. T.; Fischer, G.; Coon, J. J.; Lafontaine, I.

10.1101/119768 — evolutionary biology — Posted on 2017-08-17

710 A lumenal interrupted helix in human sperm tail microtubules

Zabeo, D.; Zabeo, D. M.; Schwartz, C. L.; Suzuki-Shinjo, A.; Morgan, G.; Widlund, P. O.; Hoog, J. L.

10.1101/088476 — cell biology — Posted on 2017-08-17

711 Structural and functional MRI from a cross-sectional Southwest University Adult lifespan Dataset (SALD)

Wei, D.; Zhuang, K.; Chen, Q.; Yang, W.; Liu, W.; Wang, K.; Sun, J.; Qiu, J.

10.1101/177279 — neuroscience — Posted on 2017-08-17

712 Deep Recurrent Neural Network Reveals a Hierarchy of Process Memory during Dynamic Natural Vision

Shi, J.; Wen, H.; Zhang, Y.; Han, K.; Liu, Z.

10.1101/177196 — neuroscience — Posted on 2017-08-17

713 When conflict cannot be avoided: executive control dominates early selective sensory modulations during cognitive conflict

Itthipuripat, S.; Deering, S.; Serences, J.

10.1101/177394 — neuroscience — Posted on 2017-08-17

714 Associations Between Nutrition, Gut Microbiome, and Health in A Novel Nonhuman Primate Model

Clayton, J. B.; Al-Ghalith, G. A.; Long, H. T.; Tuan, B. V.; Cabana, F.; Huang, H.; Vangay, P.; Ward, T.; Minh, V. V.; Tam, N. A.; Dat, N. T.; Travis, D. A.; Murtaugh, M. P.; Covert, H.; Glander, K. E.; Nadler, T.; Toddes, B.; Sha, J. C. M.; Singer, R.; Knights, D.; Johnson, T. J.

10.1101/177295 — microbiology — Posted on 2017-08-17

715 Weighted likelihood inference of genomic autozygosity patterns in dense genotype data

Blant, A.; Kwong, M.; Szpiech, Z.; Pemberton, T.

10.1101/177352 — genomics — Posted on 2017-08-17

716 Genomics of Natural Populations: Evolutionary Forces that Establish and Maintain Gene Arrangements in Drosophila pseudoosbscura

Fuller, Z. L.; Haynes, G.; Richards, S.; Schaeffer, S. W.

10.1101/177204 — genomics — Posted on 2017-08-17

717 Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

10.1101/176511 — genetics — Posted on 2017-08-17

718 Desiccation plasticity and diapause in the Argentinian pearlfish Austrolebias bellottii

Van Dooren, T.; Varela-Lasheras, I.

10.1101/177386 — evolutionary biology — Posted on 2017-08-17

719 Dynamic marine viral infections and major contribution to photosynthetic processes shown by regional and seasonal picoplankton metatranscriptomes

Sieradzki, E. T.; Ignacio-Espinoza, J. C.; Needham, D. M.; Fichot, E. B.; Fuhrman, J. A.

10.1101/176644 — ecology — Posted on 2017-08-17

720 Whole-exome sequencing of plasma cell-free DNA portrays the somatic mutation landscape of refractory metastatic colorectal cancer and enables the discovery of mutated KDR/VEGFR2 receptors as modulators of anti-angiogenic therapies.

10.1101/177287 — cancer biology — Posted on 2017-08-17

721 A Method for Quantifying Molecular Interactions Using Stochastic Modelling and Super-Resolution Microscopy

Bermudez-Hernandez, K.; Keegan, S.; Whelan, D. R.; Reid, D. A.; Zagelbaum, J.; Yin, Y.; Ma, S.; Rothenberg, E.; Fenyo, D.

10.1101/177063 — bioinformatics — Posted on 2017-08-17

722 Missing Value Imputation Approach for Mass Spectrometry-based Metabolomics Data

Wei, R.; Wang, J.; Su, M.; Jia, E.; Chen, T.; Ni, Y.

10.1101/171967 — bioinformatics — Posted on 2017-08-17

723 Cortico-Cerebellar Networks Drive Sensorimotor Learning in Speech

Lametti, D. R.; Smith, H. J.; Freidin, P.; Watkins, K. E.

10.1101/177527 — neuroscience — Posted on 2017-08-17

724 Measuring functional connectivity in stroke: approaches and considerations

Siegel, J. S.; Shulman, G. L.; Corbetta, M.

10.1101/177618 — neuroscience — Posted on 2017-08-17

725 Sleeping Beauty transposon integrates into non-TA dinucleotides via an alternative mechanism

Guo, Y.; Zhang, Y.; Hu, K.

10.1101/177584 — molecular biology — Posted on 2017-08-17

726 A Zebrafish Model For Ocular Tuberculosis

Takaki, K.; Ramakrishnan, L.; Basu, S.

10.1101/177576 — microbiology — Posted on 2017-08-17

727 Single-cell RNA sequencing reveals cell-type specific cis-eQTLs in peripheral blood mononuclear cells

van der Wijst, M. G. P.; Brugge, H.; de Vries, D. H.; Franke, L. H.

10.1101/177568 — genetics — Posted on 2017-08-17

728 Daytime eyeshine contributes to pupil camouflage in a cryptobenthic marine fish

Santon, M.; Bitton, P.-P.; Harant, U. K.; Michiels, N. K.

10.1101/177519 — evolutionary biology — Posted on 2017-08-17

729 Cdx4 regulates the onset of spinal cord neurogenesis

Joshi, P.; Darr, A. J.; Skromne, I.

10.1101/177469 — developmental biology — Posted on 2017-08-17

730 Delayed activation of the DNA replication licensing system in Lgr5(+) intestinal stem cells

Carroll, T.; Newton, I.; Blow, J. J.; Nathke, I.

10.1101/177477 — cell biology — Posted on 2017-08-17

731 Sequence-dependent nucleosome sliding in rotation-coupled and uncoupled modes revealed by molecular simulations

Niina, T.; Brandani, G. B.; Tan, C.; Takada, S.

10.1101/177436 — biophysics — Posted on 2017-08-17

732 BUSCO applications from quality assessments to gene prediction and phylogenomics

Waterhouse, R. M.; Seppey, M.; Simao Neto, F. A.; Manni, M.; Ioannidis, P.; Klioutchnikov, G.; Kriventseva, E. V.; Zdobnov, E.

10.1101/177485 — bioinformatics — Posted on 2017-08-17

733 Mapping Patient Trajectories using Longitudinal Extraction and Deep Learning in the MIMIC-III Critical Care Database

Beaulieu-Jones, B. K.; Orzechowski, P.; Moore, J. H.

10.1101/177428 — bioinformatics — Posted on 2017-08-17

734 Typical real-world locations impact the time course of object coding

Kaiser, D.; Moeskops, M. M.; Cichy, R. M.

10.1101/177493 — neuroscience — Posted on 2017-08-17

735 Transient Reduction of DNA Methylation at the Onset of Meiosis in Male Mice

Gaysinskaya, V.; Miller, B. F.; van der Heijden, G. W.; Hansen, K. D.; Bortvin, A.

10.1101/177535 — molecular biology — Posted on 2017-08-17

736 Host-pathogen interactions in urinary tract infection from the structure and diversity of urinary cell-free DNA

Burnham, P.; Dadhania, D.; Heyang, M.; Chen, F.; Suthanthiran, M.; Lee, J. R.; De Vlaminck, I.

10.1101/177402 — genomics — Posted on 2017-08-17

737 Whole-tissue stretching reveals a shape-dependent mechanism of orienting the mitotic spindle and a role for mechanical stress in cueing mitosis

Nestor-Bergmann, A.; Stooke-Vaughan, G.; Goddard, G.; Starborg, T.; Jensen, O. E.; Woolner, S.

10.1101/177592 — cell biology — Posted on 2017-08-17

738 The Epstein-Barr virus episome maneuvers between nuclear chromatin compartments during reactivation

Moquin, S. A.; Thomas, S.; Whalen, S.; Warburton, A.; Fernanadez, S. G.; McBride, A. A.; Pollard, K. S.; Miranda, J. L.

10.1101/177345 — microbiology — Posted on 2017-08-17

739 Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin against metastases in breast cancer

Wittkowski, K. M.; Dadurian, C.; Kim, H. S.; Hoshino, A.; Lyden, D.

10.1101/152405 — cancer biology — Posted on 2017-08-16

740 Ecophysiology of freshwater Verrucomicrobia inferred from metagenome-assembled genomes

He, S.; Stevens, S. L.; Chan, L.-K.; Bertilsson, S.; Glavina del Rio, T.; Tringe, S. G.; Malmstrom, R. R.; McMahon, K.

10.1101/150078 — microbiology — Posted on 2017-08-16

741 Contrasting patterns of genome-level diversity across distinct co-occurring bacterial populations

Garcia, S. L.; Stevens, S. L. R.; Crary, B.; Martinez-Garcia, M.; Stepanauskas, R.; Woyke, T.; Tringe, S. G.; Andersson, S.; Bertilsson, S.; Malmstrom, R. R.; McMahon, K. D.

10.1101/080168 — evolutionary biology — Posted on 2017-08-16

742 A Deep Learning Model for Predicting Tumor Suppressor Genes and Oncogenes from PDB Structure

Tavanaei, A.; Anandanadarajah, N.; Loganantharaj, R.

10.1101/177378 — bioinformatics — Posted on 2017-08-16

743 A computational framework for detecting signatures of accelerated somatic evolution in cancer genomes

Smith, K. S.; Ghosh, D.; Pollard, K. S.; De, S.

10.1101/177261 — bioinformatics — Posted on 2017-08-16

744 Breaking the Deadlock of Molecular Chaperones

Moran Luengo, T.; Kityk, R.; Mayer, M. P.; Rudiger, S. G. D.

10.1101/176693 — biochemistry — Posted on 2017-08-16

745 Common variants of NRXN1, LRP1B and RORA are associated with increased ventricular volumes in psychosis - GWAS findings from the B-SNIP deep phenotyping study

Alliey-Rodriguez, N.; Grey, T. A.; Shafee, R.; Padmanabhan, J.; Tandon, N.; Klinger, M.; Spring, J.; Coppes, L.; Reis, K.; Keshavan, M. S.; Gage, D.; McCarroll, S.; Bishop, J. R.; Hill, S.; Reilly, J.; Lencer, R.; Clementz, B.; Buckley, P.; Meda, S.; Narayanan, B.; Glahn, D.; Pearlson, G.; Ivleva, E.; Tamminga, C.; Sweeney, J.; Curtis, D.; Keedy, S.; Badner, J.; Liu, C.; Gershon, E. S.

10.1101/175489 — genetics — Posted on 2017-08-16

746 Psychophysiological Interactions in a Visual Checkerboard Task: Reproducibility, Reliability, and the Effects of Deconvolution

Di, X.; Biswal, B. B.

10.1101/133454 — neuroscience — Posted on 2017-08-16

747 Evolution of mechanisms that control mating in Drosophila males

Ahmed, O. M.; Shah, N. M.; Stern, D. L.; Davis, G. W.; Pollard, K. S.; Parthasarathy, S.; Avila-Herrera, A.; Tun, K. M.; Serpa, P. H.; Peng, J.; Knapp, J.-M.

10.1101/177337 — neuroscience — Posted on 2017-08-16

748 From foodwebs to gene regulatory networks (GRNs) - weak repressions by microRNAs confer system stability

Chen, Y.; Allesina, S.; Shen, Y.; Wu, C.-I.

10.1101/176701 — evolutionary biology — Posted on 2017-08-16

749 Last And Corresponding Authorship Practices In Ecology

Duffy, M. A.

10.1101/126938 — ecology — Posted on 2017-08-16

750 Distinct effects of tubulin isotype mutations on neurite growth in Caenorhabditis elegans

Zheng, C.; Diaz-Cuadros, M.; Nguyen, K.; Hall, D. H.; Chalfie, M.

10.1101/131326 — cell biology — Posted on 2017-08-16

751 MentaLiST - A fast MLST caller for large MLST schemes

Feijao, P.; Yao, H.-T.; Fornika, D.; Gardy, J.; Hsiao, W.; Chauve, C.; Chindelevitch, L.

10.1101/172858 — bioinformatics — Posted on 2017-08-16

752 ProphET, Prophage Estimation Tool: a standalone prophage sequence prediction tool with self-updating reference database

Reis-Cunha, J. L.; Bartholomeu, D. C.; Earl, A. M.; Birren, B. W.; Cerqueira, G. C.

10.1101/176750 — bioinformatics — Posted on 2017-08-16

753 Gaussian decomposition of high-resolution melt curve derivatives for measuring genome-editing efficiency

Zaboikin, M.; Freter, C.; Srinivasakumar, N.

10.1101/176719 — bioengineering — Posted on 2017-08-16

754 Hypocretin underlies the evolution of sleep loss in the Mexican cavefish

Jaggard, J. B.; Stahl, B. A.; Lloyd, E.; Prober, D. A.; Duboue, E. R.; Keene, A. C.

10.1101/122903 — neuroscience — Posted on 2017-08-16

755 Identifying drivers of parallel evolution: A regression model approach

Bailey, S. F.; Guo, Q.; Bataillon, T.

10.1101/118695 — evolutionary biology — Posted on 2017-08-16

756 Whole Root Transcriptomic Analysis Reveals a Role for Auxin Pathways in Resistance to Ralstonia solanacearum in Tomato

French, E.; Kim, B. S.; Rivera-Zuluaga, K.; Iyer-Pascuzzi, A. S.

10.1101/176685 — plant biology — Posted on 2017-08-16

757 Gradual Cerebral Hypoperfusion Impair Fear Conditioning and Object Recognition Learning and Memory in Mice: Potential Roles of Neurodegeneration and Cholinergic Dysfunction

Mehla, J.; Lacoursiere, S.; Stuart, E.; McDonald, R. J.; Mohajerani, M. H.

10.1101/177121 — neuroscience — Posted on 2017-08-16

758 Simulating Extracted Connectomes

Gornet, J.; Scheffer, L. K.

10.1101/177113 — neuroscience — Posted on 2017-08-16

759 Reward sensitivity following boredom and cognitive effort: A high-powered neurophysiological investigation

Milyavskaya, M.; Inzlicht, M.; Johnson, T.; Larson, M.

10.1101/177220 — neuroscience — Posted on 2017-08-16

760 A variant of the Morris water task for assessing learning and memory processes in mice

Mehla, J.; Faraji, J.; Saito, T.; Saido, T. C.; Mohajerani, M. H.; McDonald, R. J.

10.1101/177105 — neuroscience — Posted on 2017-08-16

761 PTE, a novel module of mammalian Polycomb Response Elements

Cameron, S. R.; Nandi, S.; Kahn, T. G.; Barrasa, J. I.; Stenberg, P.; Schwartz, Y. B.

10.1101/177097 — molecular biology — Posted on 2017-08-16

762 MicrobiomeDB: a systems biology platform for integrating, mining and analyzing microbiome experiments.

Silva de Oliveira, F.; Brestelli, J.; Cade, S.; Zheng, J.; Iodice, J.; Fisher, S.; Aurrecoechea, C.; Kissinger, J. C.; Brunk, B. P.; Stoeckert, C. J.; Fernandes, G. R.; Roos, D.; Beiting, D. P.

10.1101/176784 — microbiology — Posted on 2017-08-16

763 Epidemiology of paediatric gastrointestinal colonisation by extended spectrum cephalosporin-resistant Escherichia coli and Klebsiella pneumoniae isolates in north-west Cambodia

van Aartsen, J.; Moore, C.; Parry, C.; Turner, P.; Phot, N.; Mao, S.; Suy, K.; Davies, T.; Giess, A.; Sheppard, A.; Peto, T.; Day, N.; Crook, D.; Walker, A.; Stoesser, N.

10.1101/173294 — microbiology — Posted on 2017-08-16

764 Computational correction of cross-contamination due to exclusion amplification barcode spreading

Larsson, A. J. M.; Stanley, G.; Sinha, R.; Weissman, I. L.; Sandberg, R.

10.1101/176537 — genomics — Posted on 2017-08-16

765 Landscape of human miRNA variation and conservation using Annotative Database of miRNA Elements, ADmiRE

Oak, N.; Ghosh, R.; Plon, S. E.

10.1101/177170 — genomics — Posted on 2017-08-16

766 Large-Scale cognitive GWAS Meta-analysis Reveals Tissue-Specific Neural Expression and Potential Nootopic Drug Targets

Lam, M.; Trampush, J. W.; Yu, J.; Knowles, E.; Davies, G.; Liewald, D. C.; Starr, J. M.; Djurovic, S.; Melle, I.; Sundet, K.; Christoforou, A.; Reinvang, I.; DeRosse, P.; Lundervold, A. J.; Steen, V. M.; Espeseth, T.; Raikkonen, K.; Widen, E.; Palotie, A.; Eriksson, J. G.; Giegling, I.; Konte, B.; Roussos, P.; Giakoumaki, S.; Burdick, K. E.; Payton, A.; Ollier, W.; Chiba-Falek, O.; Attix, D. K.; Need, A. C.; Cirulli, E. T.; Voineskos, A. N.; Stefanis, N. C.; Avramopoulos, D.; Hatzimanolis, A.; Arking, D. E.; Smyrnis, N.; Bilder, R. M.; Freimer, N. A.; Cannon, T. D.; London, E.; Poldrack, R. A.

10.1101/176842 — genomics — Posted on 2017-08-16

767 Progressively more subtle aggregation avoidance strategies mark a long-term direction to protein evolution

Foy, S. G.; Wilson, B. A.; Cordes, M. H. J.; Masel, J.

10.1101/176867 — evolutionary biology — Posted on 2017-08-16

768 Positively selected effector genes and their contribution to virulence in the smut fungus Sporisorium reilianum

Schweizer, G.; Munch, K.; Mannhaupt, G.; Schirawski, J.; Kahmann, R.; Dutheil, J.

10.1101/177022 — evolutionary biology — Posted on 2017-08-16

769 Co-occurring soil bacteria exhibit a robust competitive hierarchy and lack of non-transitive interactions

Higgins, L. M.; Friedman, J.; Shen, H.; Gore, J.

10.1101/175737 — ecology — Posted on 2017-08-16

770 Disruption of the interfacial membrane leads to Magnaporthe oryzae effector re-location and lifestyle switch during rice blast disease

Jones, K.; Zhu, J.; Jenkinson, C. B.; Kim, D. W.; Khang, C. H.

10.1101/177147 — cell biology — Posted on 2017-08-16

771 A Low-Cost Multiplex Biomarker Assay Stratifies Colorectal Cancer Patient Samples into Clinically-Relevant Subtypes

Ragulan, C.; Eason, K.; Nyamundanda, G.; Patil, Y.; Poudel, P.; Fontana, E.; Del Rio, M.; Koo, S.-L.; Tan, W. S.; Martineau, P.; Cunningham, D.; Tan, I.; Sadanandam, A.

10.1101/174847 — cancer biology — Posted on 2017-08-16

772 Hydrogen peroxide formation by Nox4 limits malignant transformation

Helfinger, V.; Freiherr von Gall, F.; Henke, N.; Kunze, M. M.; Schmid, T.; Heidler, J.; Wittig, I.; Radecke, H. H.; Marschall, V.; Anderson, K.; Shah, A. M.; Fulda, S.; Brune, B.; Brandes, R. P.; Schroder, K.

10.1101/177055 — cancer biology — Posted on 2017-08-16

773 OligoMiner: A rapid, flexible environment for the design of genome-scale oligonucleotide in situ hybridization probes

Beliveau, B. J.; Kishi, J. Y.; Nir, G.; Sasaki, H. M.; Saka, S. K.; Nguyen, S. C.; Wu, C.-t.; Yin, P.

10.1101/171504 — bioinformatics — Posted on 2017-08-16

774 Concept and in-silico assessment of an algorithm for monitoring cytosolic fluorescent aggregates in cells.

Garces Suarez, Y.; Perez Koldenkova, V.; Matsuda, T.; Guerrero, A.; Nagai, T.

10.1101/177139 — bioinformatics — Posted on 2017-08-16

775 The Oyster River Protocol: A Multi Assembler and Kmer Approach For de novo Transcriptome Assembly

MacManes, M. D.

10.1101/177253 — bioinformatics — Posted on 2017-08-16

776 Impairment of zebrafish reproduction upon exposure to TDCPP

Liu, X.; Jia, G.

10.1101/176909 — pharmacology and toxicology — Posted on 2017-08-16

777 An atlas of genetic associations in UK Biobank

Canela-Xandri, O.; Rawlik, K.; Tenesa, A.

10.1101/176834 — genomics — Posted on 2017-08-16

778 Detection and removal of barcode swapping in single-cell RNA-seq data

Griffiths, J. A.; Lun, A. T. L.; Richard, A. C.; Bach, K.; Marioni, J. C.

10.1101/177048 — genomics — Posted on 2017-08-16

779 Genome-wide analysis of risk-taking behaviour and cross-disorder genetic correlations in 116,255 individuals from the UK Biobank cohort

Strawbridge, R. J.; Ward, J.; Cullen, B.; Tunbridge, E. M.; Hartz, S.; Bierut, L.; Horton, A.; Bailey, M. E. S.; Graham, N.; Ferguson, A.; Lyall, D. M.; Mackay, D.; Pidgeon, L. M.; Cavanagh, J.; Pell, J. P.; O'Donovan, M.; Escott-Price, V.; Harrison, P. J.; Smith, D. J.

10.1101/177014 — genetics — Posted on 2017-08-16

780 Sex-biased gene expression resolves sexual conflict through the evolution of sex-specific genetic architecture

Wright, A. E.; Fumagalli, M.; Cooney, C. R.; Bloch, N. I.; Vieira, F. G.; Buechel, S. D.; Kolm, N.; Mank, J. E.

10.1101/176990 — evolutionary biology — Posted on 2017-08-16

781 Disruption of thyroid endocrine in zebrafish exposed to BDE-209

Li, D.; Wang, X.

10.1101/176917 — developmental biology — Posted on 2017-08-16

782 Variable dose analysis: A novel RNAi-based method for detection of synthetic lethal interactions

Housden, B. E.; Li, Z.; Kelley, C.; Wang, Y.; Hu, Y.; Valvezan, A. J.; Manning, B. D.; Perrimon, N.

10.1101/176974 — cancer biology — Posted on 2017-08-16

783 Small Molecules Attenuate the Interplay between Conformational Fluctuations, Early Oligomerization and Amyloidosis of Alpha Synuclein

Kundu, A.; Ghosh, S.; Chattopadhyay, K.

10.1101/177006 — biophysics — Posted on 2017-08-16

784 Serial representation of items during working memory maintenance at letter-selective cortical sites

Bahramisharif, A.; Jensen, O.; Jacobs, J.; Lisman, J.

10.1101/171660 — neuroscience — Posted on 2017-08-16

785 Balancing the Local and the Universal in Maintaining Ethical Access to a Genomics Biobank

Heeney, C.; Kerr, S. M.

10.1101/157024 — genomics — Posted on 2017-08-16

786 Horizontal gene cluster transfer increased hallucinogenic mushroom diversity

Reynolds, H. T.; Vijayakumar, V.; Gluck-Thaler, E.; Korotkin, H. B.; Matheny, P. B.; Slot, J. C.

10.1101/176347 — evolutionary biology — Posted on 2017-08-16

787 Correlations, interactions, and predictability in virus-microbe networks

Coenen, A. R.; Weitz, J. S.

10.1101/176628 — ecology — Posted on 2017-08-16

788 SiFit: A Method for Inferring Tumor Trees from Single-Cell Sequencing Data under Finite-site Models

Zafar, H.; Tzen, A.; Navin, N.; Chen, K.; Nakhleh, L.

10.1101/091595 — bioinformatics — Posted on 2017-08-16

789 N6-Methyladenine DNA Modification in Human Genome

Xiao, C.-L.; Zhu, S.; He, M.-H.; Chen, Y.; Yu, G.-L.; Chen, D.; Xie, S.-Q.; Luo, F.; Liang, Z.; Gu, X.-F.; Wang, K.; Yan, G.-R.

10.1101/176958 — genomics — Posted on 2017-08-16

790 Chemical control of a CRISPR-Cas9 acetyltransferase

Shrimp, J. H.; Grose, C.; Widmeyer, S. R. T.; Jadhav, A.; Meier, J. L.

10.1101/176875 — biochemistry — Posted on 2017-08-16

791 Conformational states during vinculin unlocking differentially regulate focal adhesion properties

Chorev, D. S.; Volberg, T.; Livne, A.; Eisenstein, M.; Martins, B.; Kam, Z.; Jockusch, B.; Medalia, O.; Sharon, M.; Geiger, B.

10.1101/176586 — biochemistry — Posted on 2017-08-16

792 Frequent lack of repressive capacity of promoter DNA methylation identified through genome-wide epigenomic manipulation

Ford, E. E.; Grimmer, M. R.; Stolzenburg, S.; Bogdanovic, O.; de Mendoza, A.; Farnham, P. J.; Blancafort, P.; Lister, R.

10.1101/170506 — genomics — Posted on 2017-08-16

793 Spontaneous activity synchronizes whisker-related sensorimotor networks prior to their maturation in the developing rat cortex

McVea, D. A.; Murphy, T. H.; Mohajerani, M. H.

10.1101/176800 — neuroscience — Posted on 2017-08-15

794 Towards a reliable, automated method of individual alpha frequency (IAF) quantification

Corcoran, A. W.; Alday, P. M.; Schlesewsky, M.; Bornkessel-Schlesewsky, I.

10.1101/176792 — bioinformatics — Posted on 2017-08-15

795 Searching for Correlated Conformational Dynamics: Analysis of the NMR Relaxation Dispersions with Akaike's Information Theory and Hierarchical Clustering

Kovrigin, E. L.

10.1101/176776 — biochemistry — Posted on 2017-08-15

796 On the bioconversion of dietary carotenoids to astaxanthin and its distribution in the marine copepod, Tigriopus californicus

Weaver, R. J.; Cobine, P. A.; Hill, G. E.

10.1101/174300 — zoology — Posted on 2017-08-15

797 Discovery and whole genome sequencing of a human clinical isolate of the novel species Klebsiella quasivariicola sp. nov.

Long, S. W.; Linson, S. E.; Saavedra, M. O.; Cantu, C.; Davis, J. J.; Brettin, T.; Olsen, R. J.

10.1101/176743 — microbiology — Posted on 2017-08-15

798 Interactions between species introduce spurious associations in microbiome studies

Menon, R.; Ramanan, V.; Korolev, K. S.

10.1101/176677 — microbiology — Posted on 2017-08-15

799 A global envelope test to detect early and late bursts of trait evolution

Murrell, D. J.

10.1101/175968 — evolutionary biology — Posted on 2017-08-15

800 The genomic rate of adaptation in the fungal wheat pathogen Zymoseptoria tritici

Grandaubert, J.; Dutheil, J. Y.; Stukenbrock, E. H.

10.1101/176727 — evolutionary biology — Posted on 2017-08-15

801 ProphET, Prophage Estimation Tool: a standalone prophage sequence prediction tool with self-updating reference database

Reis-Cunha, J. L.; Bartholomeu, D. C.; Birren, B. W.; Cerqueira, G. C.

10.1101/176750 — bioinformatics — Posted on 2017-08-15

802 From foodwebs to gene regulatory networks (GRNs) - weak repressions by microRNAs confer system stability

Chen, Y.; Allesina, S.; Shen, Y.; Wu, C.-I.

10.1101/176701 — evolutionary biology — Posted on 2017-08-15

803 Correlations, interactions, and predictability in virus-microbe networks

Coenen, A. R.; Weitz, J. S.

10.1101/176628 — ecology — Posted on 2017-08-15

804 Twenty-five species of frogs in a liter of water: eDNA survey for exploring tropical frog diversity

Balint, M.; Nowak, C.; Marton, O.; Pauls, S.; Wittwer, C.; Aramayo, J. L.; Schulze, A.; Chambert, T.; Cocchiararo, B.; Jansen, M.

10.1101/176065 — ecology — Posted on 2017-08-15

805 The antibody repertoire of colorectal cancer

Cha, S. W.; Bonissone, S.; Na, S.; Pevzner, P. A.; Bafna, V.

10.1101/176768 — bioinformatics — Posted on 2017-08-15

806 Molecular determinants and bottlenecks in the unbinding dynamics of biotin-streptavidin

Tiwary, P.

10.1101/176594 — biochemistry — Posted on 2017-08-15

807 Breaking the Deadlock of Molecular Chaperones

Moran Luengo, T.; Kityk, R. B.; Mayer, M. P.; Rudiger, S. G. D.

10.1101/176693 — biochemistry — Posted on 2017-08-15

808 The Plastid Genome In Cladophorales Green Algae Is Encoded By Hairpin Plasmids

Del Cortona, A.; Leliaert, F.; Bogaert, K. A.; Turmel, M.; Boedeker, C.; Janouskovec, J.; Lopez-Bautista, J. M.; Verbruggen, H.; Vandepoele, K.; De Clerck, O.

10.1101/145037 — genomics — Posted on 2017-08-15

809 Adaptation of the Arizona Cognitive Task Battery for use with the Ts65Dn Mouse Model of Down Syndrome

Hunsaker, M. R.; Smith, G. K.; Kesner, R. P.

10.1101/061754 — animal behavior and cognition — Posted on 2017-08-15

810 SINHCAF/FAM60A links SIN3A function to the hypoxia response and its levels are predictive of cancer patient survival

Biddlestone, J.; Batie, M.; Shmakova, A.; Bandarra, D.; Knatko, E. V.; Dinkova-Kostova, A. T.; Munoz, I.; Sundaramoorthy, R.; Owen-Hughes, T.; Rocha, S.

10.1101/176032 — molecular biology — Posted on 2017-08-15

811 De novo Clustering Nanopore Long Reads of Transcriptomics Data by Gene

Marchet, C.; Lecompte, L.; Da Silva, C.; Cruaud, C.; Aury, J. M.; Nicolas, J.; Peterlongo, P.

10.1101/170035 — bioinformatics — Posted on 2017-08-15

812 The effect of sequence mismatches on binding affinity and endonuclease activity are decoupled throughout the Cas9 binding site

Zhang, L.; Rube, H. T.; Bussemaker, H. J.; Pufall, M. A.

10.1101/176255 — biochemistry — Posted on 2017-08-15

813 Outer membrane lipid homeostasis via retrograde phospholipid transport in Escherichia coli

Shrivastava, R.; Jiang, X.; Chng, S. S.

10.1101/109884 — microbiology — Posted on 2017-08-15

814 Hemagglutinin Glycan Clock Guides Human Influenza A Virus Evolution

Altman, M. O.; Angel, M.; Kosik, I.; Gibbs, J. S.; Trovao, N. S.; Zost, S. J.; Hensley, S. E.; Nelson, M. I.; Yewdell, J. W.

10.1101/163345 — microbiology — Posted on 2017-08-15

815 Nonparametric Bayesian inference of transcriptional branching and recombination identifies regulators of early human germ cell development

Penfold, C. A.; Sybirna, A.; Reid, J.; Huang, Y.; Wernisch, L.; Ghahramani, Z.; Grant, M.; Surani, M. A.

10.1101/167684 — developmental biology — Posted on 2017-08-15

816 A randomized placebo-controlled trial on the antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression

Palhano-Fontes, F.; Barreto, D.; Onias, H.; Andrade, K. C.; Novaes, M.; Pessoa, J.; Mota-Rolim, S.; Osorio, F. L.; Sanches, R.; dos Santos, R.; Tofoli, L.; Silveira, G.; Yonamine, M.; Riba, J.; Santos, F. R.; Silva-Junior, A. A.; Alchieri, J.; Galvao-Coelho, N.; Lobao-Soares, B.; Hallak, J.; Arcoverde, E.; Maia-de-Oliveira, J.; de Araujo, D. B.

10.1101/103531 — clinical trials — Posted on 2017-08-15

817 Early afterdepolarisation tendency as a simulated pro-arrhythmic risk indicator

McMillan, B.; Gavaghan, D. J.; Mirams, G.

10.1101/176560 — pharmacology and toxicology — Posted on 2017-08-15

818 Metabolomic profiling reveals effects of marein on energy metabolism in HepG2 cells

Jiang, B.; Le, L.; Hu, K.; Xu, L.; Xiao, P.

10.1101/176495 — pharmacology and toxicology — Posted on 2017-08-15

819 The measurement of species selection on evolving characters

Simpson, C.

10.1101/176438 — paleontology — Posted on 2017-08-15

820 Requirements for coregistration accuracy in on-scalp MEG

Zetter, R.; Iivanainen, J.; Stenroos, M.; Parkkonen, L.

10.1101/176545 — neuroscience — Posted on 2017-08-15

821 The evolutionary dynamics of influenza A virus within and between human hosts

McCrone, J. T.; Woods, R. J.; Martin, E. T.; Malosh, R. E.; Monto, A. S.; Lauring, A. S.

10.1101/176362 — microbiology — Posted on 2017-08-15

822 Genomics-Based Identification of Microorganisms in Human Ocular Body Fluid

Kirstahler, P.; Solborg Bjerrum, S.; Friis-Moller, A.; la Cour, M.; Aarestrup, F. M.; Westh, H.; Pamp, S. J.

10.1101/176529 — microbiology — Posted on 2017-08-15

823 Metagenomic Insights into The Diversity and Functions of Microbial Assemblages in Tasik Kenyir Ecosystem

Mohd Noor, M. E.; Syed Jamil Fadaak, S. N. E.; Mat Isa, M. N.; Abu Bakar, M. F.; Abdullah, M. D.-D.

10.1101/176453 — microbiology — Posted on 2017-08-15

824 Modeling the emergence of antibiotic resistance in the environment: an analytical solution for the minimum selection concentration

Greenfield, B. K.; Shaked, S.; Marrs, C. F.; Nelson, P.; Raxter, I.; Xi, C.; McKone, T. E.; Jolliet, O.

10.1101/176289 — microbiology — Posted on 2017-08-15

825 Novel metrics for quantifying bacterial genome composition skews

Joesch-Cohen, L. M.; Robinson, M.; Jabbari, N.; Lausted, C.; Glusman, G.

10.1101/176370 — genomics — Posted on 2017-08-15

826 A pan cancer analysis of promoter activity highlights the regulatory role of alternative transcription start sites and their association with noncoding mutations

Demircioglu, D.; Kindermans, M.; Nandi, T.; Cukuroglu, E.; Calabrese, C.; Fonseca, N. A.; Kahles, A.; Lehmann, K.; Stegle, O.; PCAWG-3, ; PCAWG-Network, ; Brazma, A.; Brooks, A.; Rätsch, G.; Tan, P.; Göke, J.

10.1101/176487 — genomics — Posted on 2017-08-15

827 Genome-wide Enhancer Maps Differ Significantly in Genomic Distribution, Evolution, and Function

Benton, M. L.; Talipineni, S. C.; Kostka, D.; Capra, J. A.

10.1101/176610 — genetics — Posted on 2017-08-15

828 Horizontal gene cluster transfer increased hallucinogenic mushroom diversity

Reynolds, H. T.; Vijayakumar, V.; Gluck-Thaler, E.; Korotkin, H. B.; Matheny, P. B.; Slot, J. C.

10.1101/176347 — evolutionary biology — Posted on 2017-08-15

829 Co-estimating Reticulate Phylogenies and Gene Trees from Multi-locus Sequence Data

Wen, D.; Nakhleh, L.

10.1101/095539 — evolutionary biology — Posted on 2017-08-15

830 The Complex Ecosystem in Non Small Cell Lung Cancer Invasion

Haney, S.; Konen, J.; Marcus, A. I.; Bazhenov, M.

10.1101/176446 — cancer biology — Posted on 2017-08-15

831 Evaluating a topic model approach for parsing microbiome data structure

Woloszynek, S.; Zhao, Z.; Simpson, G.; O'Connor, M. P.; Mell, J. C.; Rosen, G. L.

10.1101/176412 — bioinformatics — Posted on 2017-08-15

832 Large-scale determination and characterization of cell type-specific regulatory elements in the human genome

Wang, C.; Zhang, S.

10.1101/176602 — bioinformatics — Posted on 2017-08-15

833 The case for species selection

Simpson, C.

10.1101/084046 — paleontology — Posted on 2017-08-15

834 PrPSc-induced conformational changes and strain-specific structures of PrPSc revealed by Disulfide-crosslink scanning

Taguchi, Y.; Nishida, N.; Schatzl, H.

10.1101/175919 — molecular biology — Posted on 2017-08-15

835 Solagigasbacteria: Lone genomic giants among the uncultured bacterial phyla

Becraft, E.; Woyke, T.; Jarett, J.; Ivanaova, N.; Onstott, T.; Don Lau, M.; Godoy Vitorino, F.; Brown, J.; Poulton, N.; Brown, J.; Esien, J.; Moser, D.; Stepanauskas, R.

10.1101/176263 — microbiology — Posted on 2017-08-15

836 mixOmics: an R package for ‘omics feature selection and multiple data integration

Rohart, F.; Gautier, B.; Singh, A.; Le Cao, K.-A.

10.1101/108597 — bioinformatics — Posted on 2017-08-15

837 Quantifying the thermostability landscape separating plant sesquiterpene synthase orthologs using Maximum Entropy

Nartey, C. M.; Aljadeff, J.; Fernandez, I.; Laurendon, C.; Koo, H. J.; O'Maille, P. E.; Sharpee, T. O.; Noel, J. P.

10.1101/172437 — bioengineering — Posted on 2017-08-15

838 Activity-induced Ca2+ signaling in perisynaptic Schwann cells is mediated by P2Y1 receptors and regulates muscle fatigue

Heredia, D. J.; Feng, C.; Hennig, G. W.; Gould, T. W.

10.1101/176354 — neuroscience — Posted on 2017-08-15

839 The somatically generated T cell receptor CDR3a contributes to the MHC allele specificity of the T cell receptor

Marrack, P.; Krovi, S. H.; Silberman, D.; White, J.; Kushnir, E.; Nakayama, M.; Crook, J.; Danhorn, T.; Leach, S.; Anselment, R.; Scott-Browne, J.; Gapin, L.; Kappler, J.

10.1101/176388 — immunology — Posted on 2017-08-15

840 PANOPLY: A computational method for identification of promising drugs for a patient based on multidimensional data

Kalari, K. R.; Sinnwell, J. P.; Thompson, K. J.; Tang, X.; Carlson, E. E.; Yu, J.; Vedell, P. T.; Ingle, J. N.; Weinshilboum, R.; Wang, L.; Boughey, J. C.; Goetz, M. P.; Suman, V. J.

10.1101/176396 — bioinformatics — Posted on 2017-08-15

841 Curatr: a web application for creating, curating, and sharing a mass spectral library

Palmer, A.; Phapale, P.; Fay, D.; Alexandrov, T.

10.1101/170571 — bioinformatics — Posted on 2017-08-15

842 3D Single-Molecule Super-Resolution Microscopy With A Tilted Light Sheet

Gustavsson, A.-K.; Petrov, P. N.; Lee, M. Y.; Shechtman, Y.; Moerner, W. E.

10.1101/135699 — biophysics — Posted on 2017-08-14

843 The effect of sequence mismatches on binding affinity and endonuclease activity are decoupled throughout the Cas9 binding site

Zhang, L.; Rube, H. T.; Bussemaker, H. J.; Pufall, M. A.

10.1101/176255 — biochemistry — Posted on 2017-08-14

844 Population-based mechanistic modeling allows for quantitative predictions of drug responses across cell types

Gong, J. Q. X.; Sobie, E. A.

10.1101/176321 — systems biology — Posted on 2017-08-14

845 SelexGLM differentiates androgen and glucocorticoid receptor DNA-binding preference over an extended binding site

Zhang, L.; Martini, G.; Rube, H. T.; Kribelbauer, J. F.; Rastogi, C.; FitzPatrick, V. D.; Houtman, J. C.; Bussemaker, H. J.; Pufall, M. A.

10.1101/176073 — systems biology — Posted on 2017-08-14

846 Network inference reveals novel connections in pathways regulating growth and defense in the yeast salt response

MacGilvray, M. E.; Shishkova, E.; Chasman, D.; Place, M.; Gitter, A.; Coon, J. J.; Gasch, A. P.

10.1101/176230 — systems biology — Posted on 2017-08-14

847 A retrieved context model of the emotional modulation of memory

Talmi, D.; Lohnas, L.; Daw, N.

10.1101/175653 — neuroscience — Posted on 2017-08-14

848 Prestimulus Activity in the Cingulo-Opercular Network Predicts Memory for Naturalistic Episodic Experience

Cohen, N.; Ben-Yakov, A.; Weber, J.; Edelson, M.; Paz, R.; Dudai, Y.

10.1101/176057 — neuroscience — Posted on 2017-08-14

849 Encoding Sensory and Motor Patterns as Time-Invariant Trajectories in Recurrent Neural Networks

Goudar, V.; Buonomano, D. V.

10.1101/176198 — neuroscience — Posted on 2017-08-14

850 Dlic1 deletion impaired cerebellar development in mouse

Kong, S.; Tao, W.

10.1101/176339 — neuroscience — Posted on 2017-08-14

851 HNRNPA1 promotes recognition of splice site decoys by U2AF2 in vivo

Howard, J. M.; Lin, H.; Kim, G.; Draper, J. M.; Haeussler, M.; Katzman, S.; Toloue, M.; Liu, Y.; Sanford, J. R.

10.1101/175901 — molecular biology — Posted on 2017-08-14

852 The Mediator co-activator complex regulates Ty1 retromobility via alternative transcription start site selection

Salinero, A. C.; Knoll, E. R.; Zhu, Z. I.; Landsman, D.; Curcio, M. J.; Morse, R. H.

10.1101/176248 — molecular biology — Posted on 2017-08-14

853 N-terminal sumoylation of centromeric histone H3 variant Cse4 regulates its proteolysis to prevent mislocalization to non-centromeric chromatin

Ohkuni, K.; Levy-Myers, R.; Warren, J.; Au, W.-C.; Takahashi, Y.; Baker, R. E.; Basrai, M.

10.1101/176206 — molecular biology — Posted on 2017-08-14

854 SINHCAF/FAM60A links SIN3A function to the hypoxia response and its levels are predictive of cancer patient survival

Biddlestone, J.; Batie, M.; Shmakova, A.; Bandarra, D.; Knatko, E. V.; Dinkova-Kostova, A. T.; Munoz, I.; Sundaramoorthy, R.; Owen-Hughes, T.; Rocha, S.

10.1101/176032 — molecular biology — Posted on 2017-08-14

855 Deciphering Functional Redundancy in the Human Microbiome

Tian, L.; Wu, A.-K.; Friedman, J.; Waldor, M. K.; Weiss, S. T.; Liu, Y.-Y.

10.1101/176313 — microbiology — Posted on 2017-08-14

856 A nutrient-dependent division antagonist is regulated post-translationally by the Clp proteases in Bacillus subtilis

Hill, N. S.; Zuke, J. D.; Buske, P. J.; Chien, A.-C.; Levin, P. A.

10.1101/176222 — microbiology — Posted on 2017-08-14

857 Transcriptome wide analysis of natural antisense transcripts shows their potential role in breast cancer.

Wenric, S.; ElGuendi, S.; Caberg, J.-H.; Bezzaou, W.; Fasquelle, C.; Charloteaux, B.; Karim, L.; Hennuy, B.; Freres, P.; Collignon, J.; Boukerroucha, M.; Schroeder, H.; Olivier, F.; Jossa, V.; Jerusalem, G.; Josse, C.; Bours, V.

10.1101/176164 — genomics — Posted on 2017-08-14

858 High-quality genome assemblies uncover caste-specific long non-coding RNAs in ants

Shields, E. J.; Bonasio, R.

10.1101/155119 — genomics — Posted on 2017-08-14

859 The helicase domain of Polθ counteracts RPA to promote alt-NHEJ

Mateos-Gomez, P. A.; Kashkina, E.; Pomerantz, R.; Kent, T.; Sfeir, A.

10.1101/176271 — genetics — Posted on 2017-08-14

860 Environmental fluctuations accelerate molecular evolution of thermal tolerance in a marine diatom

Schaum, C.- E.; Buckling, A.; Smirnoff, N.; Studholme, D.; Yvon-Durocher, G.

10.1101/176040 — evolutionary biology — Posted on 2017-08-14

861 The effect of the thin body ideal in a media-naive population

Jucker, J.-L.; Thornborrow, T.; Boothroyd, L.; Tovee, M.

10.1101/176107 — evolutionary biology — Posted on 2017-08-14

862 A network modeling approach to elucidate drug resistance mechanisms and predict combinatorial drug treatments in breast cancer

Gomez Tejeda Zanudo, J.; Albert, R.

10.1101/176214 — cancer biology — Posted on 2017-08-14

863 Revealing unidentified heterogeneity in different epithelial cancers using heterocellular subtype classification

Poudel, P.; Nyamundanda, G.; Ragulan, C.; Lawlor, R.; Das, K.; Tan, P.; Scarpa, A.; Sadanandam, A.

10.1101/175505 — bioinformatics — Posted on 2017-08-14

864 Beer produced via hydrodynamic cavitation retains higher amounts of xanthohumol and other hops prenylflavonoids

Ciriminna, R.; Albanese, L.; Di Stefano, V.; Delisi, R.; Avellone, G.; Meneguzzo, F.; Pagliaro, M.

10.1101/176131 — biochemistry — Posted on 2017-08-14

865 The effect of sequence mismatches on binding affinity and endonuclease activity are decoupled throughout the Cas9 binding site

Zhang, L.; Rube, H. T.; Bussemaker, H. J.; Pufall, M. A.

10.1101/176255 — biochemistry — Posted on 2017-08-14

866 Lesion evidence for a critical role of left posterior but not frontal areas in alpha-beta power decreases during context-driven word production

Piai, V.; Rommers, J.; Knight, R. T.

10.1101/150748 — neuroscience — Posted on 2017-08-14

867 Preliminary Report on the Impact of Smartglasses-based Behavioral and Social Communication Aid on Hyperactivity in Children and Adults with Autism.

Vahabzadeh, A.; Keshav, N. U.; Salisbury, J. P.; Sahin, N. T.

10.1101/165514 — neuroscience — Posted on 2017-08-14

868 Predicting how and when hidden neurons skew measured synaptic interactions

Brinkman, B. A. W.; Rieke, F.; Shea-Brown, E.; Buice, M. A.

10.1101/105510 — neuroscience — Posted on 2017-08-14

869 But will they even wear it? Exploring the tolerability of social communication coaching smartglasses in children and adults with autism.

Keshav, N. U.; Salisbury, J. P.; Vahabzadeh, A.; Sahin, N. T.

10.1101/164376 — neuroscience — Posted on 2017-08-14

870 Dorsal Anterior Cingulate-Midbrain Ensemble As A Reinforcement Meta-Learner

Silvetti, M.; Vassena, E.; Abrahamse, E.; Verguts, T.

10.1101/130195 — neuroscience — Posted on 2017-08-14

871 Caloric-restriction mitigates age-associated alteration in CG and non-CG methylation in the old brain.

Hadad, N.; Unnikrishnan, A.; Jackson, J. A.; Masser, D. R.; Otalora, L.; Stanford, D. R.; Richardson, A.; Freeman, W.

10.1101/175810 — neuroscience — Posted on 2017-08-14

872 The whole diagram of the discovered host immunological pathways

Hu, W.

10.1101/006965 — immunology — Posted on 2017-08-14

873 An Amino Acid Motif In HLA-DRB1 Distinguishes Patients With Uveitis In Juvenile Idiopathic Arthritis

Haasnoot, A. J. W.; Schilham, M. W.; Kamphuis, S. S. M.; Hissink Muller, P. C. E.; Heiligenhaus, A.; Foll, D.; Ophoff, R. A.; Minden, K.; Radstake, T. R. D. J.; Den Hollander, A. I.; Reinards, T. H. C. M.; Hiddingh, S.; Schalij-Delfos, N.; Hoppenreijs, E. P. A. H.; van Rossum, M. A. J.; Wouters, C.; Saurenmann, R. K.; Wulffraat, N.; ICON-JIA Study Group, ; ten Cate, R.; de Boer, J. H.; Pulit, S. L.; Kuiper, J. J. W.

10.1101/140954 — genetics — Posted on 2017-08-14

874 De Novo Mutations Implicate Novel Genes With Burden Of Rare Variants In Systemic Lupus Erythematosus

Pullabhatla, V.; Roberts, A. L.; Lewis, M. J.; Mauro, D.; Morris, D. L.; Odhams, C. A.; Tombleson, P.; Liljedahl, U.; Vyse, S.; Simpson, M. A.; Sauer, S.; de Rinaldis, E.; Syvänen, A.-C.; Vyse, T. J.

10.1101/139238 — genetics — Posted on 2017-08-14

875 Rare earth elements (REE) in freshwater, marine, and terrestrial ecosystems in the eastern Canadian Arctic

MacMillan, G. A.; Chetelat, J.; Heath, J.; Mickpegak, R.; Amyot, M.

10.1101/174870 — ecology — Posted on 2017-08-14

876 Intrauterine position probabilities in mice, rats and gerbils

Mulley, J. F.; Kuncheva, L. I.

10.1101/173153 — developmental biology — Posted on 2017-08-14

877 Recasting the cancer stem cell hypothesis: unification using a continuum model of microenvironmental forces

Scott, J. G.; Dhawan, A.; Hjelmeland, A.; Lathia, J.; Chumakova, A.; Hitomi, M.; Fletcher, A. G.; Maini, P. K.; Anderson, A. R. A.

10.1101/169615 — cancer biology — Posted on 2017-08-14

878 Euplotid: A Linux-based platform to physically edit the genome

Borges, D.

10.1101/170159 — biophysics — Posted on 2017-08-14

879 mixOmics: an R package for ‘omics feature selection and multiple data integration

Rohart, F.; Gautier, B.; Singh, A.; Le Cao, K.-A.

10.1101/108597 — bioinformatics — Posted on 2017-08-14

880 The Novel Monocomponent FAD-dependent Monooxygenase HpaM Catalyzes the 2-Decarboxylative Hydroxylation of 5-Hydroxypicolinic Acid in Alcaligenes faecalis JQ135

Qiu, J.; Liu, B.; Zhao, L.; Zhang, Y.; Cheng, D.; Yan, X.; Jiang, J.; Hong, Q.; He, J.

10.1101/171595 — microbiology — Posted on 2017-08-14

881 Nanopore sequencing enables near-complete de novo assembly of Saccharomyces cerevisiae reference strain CEN.PK113-7D

Salazar, A. N.; Gorter de Vries, A. R.; van den Broek, M.; Wijsman, M.; de la Torre Cortes, P.; Brickwedde, A.; Brouwers, N.; Daran, J.-M. G.; Abeel, T.

10.1101/175984 — genomics — Posted on 2017-08-14

882 Real-time genomic and epidemiological investigation of a multi-institution outbreak of KPC-producing Enterobacteriaceae: a translational study

Kwong, J. C.; Lane, C.; Romanes, F.; Goncalves da Silva, A.; Easton, M.; Cronin, K.; Waters, M. J.; Tomita, T.; Stevens, K.; Schultz, M. B.; Baines, S. L.; Sherry, N. L.; Carter, G.; Mu, A.; Sait, M.; Ballard, S. A.; Seemann, T.; Stinear, T. P.; Howden, B. P.

10.1101/175950 — genomics — Posted on 2017-08-14

883 Continuous gene flow contributes to low global species abundance and distribution of a marine model diatom

Rastogi, A.; Deton-Cabanillas, A.-F.; Rocha Jimenez Vieira, F.; Veluchamy, A.; Cantrel, C.; Wang, G.; Vanormelingen, P.; Bowler, C.; Piganeau, G.; Tirichine, L.; Hu, H.

10.1101/176008 — genomics — Posted on 2017-08-14

884 Global accumulation of circRNAs during aging in Caenorhabditis elegans

Cortes-Lopez, M.; Gruner, M.; Cooper, D. A.; Gruner, H. N.; Voda, A.-I.; van der Linden, A.; Miura, P.

10.1101/175026 — genomics — Posted on 2017-08-14

885 Somatic genome editing with the RCAS/TVA-CRISPR/Cas9 system for precision tumor modeling

Oldrini, B.; Curiel-Garcia, A.; Marques, C.; Matia, V.; Uluckan, O.; Torres-Ruiz, R.; Rodriguez-Perales, S.; Huse, J.; Squatrito, M.

10.1101/162669 — cancer biology — Posted on 2017-08-14

886 Integrative analysis of large scale transcriptome data draws a comprehensive landscape of Phaeodactylum tricornutum functional genome and evolutionary origin of diatoms

Rastogi, A.; Maheswari, U.; Dorrell, R. G.; Maumus, F.; Rocha Jimenez Vieira, F.; Kustka, A.; McCarthy, J.; Allen, A. E.; Kersey, P.; Bowler, C.; Tirichine, L.

10.1101/176024 — bioinformatics — Posted on 2017-08-14

887 A stable beneficial symbiotic relationship between endophytic fungus Schizophyllum commune and host plant Panax ginseng

Zhai, X.; Chen, L.; Jia, M.; Li, C. H.; Shen, H.; Ye, B. Z.; Qin, L. P.; Han, T.

10.1101/175885 — plant biology — Posted on 2017-08-14

888 HNRNPA1 promotes recognition of splice site decoys by U2AF2 in vivo

Howard, J. M.; Lin, H.; Kim, G.; Draper, J. M.; Haeussler, M.; Katzman, S.; Toloue, M.; Liu, Y.; Sanford, J. R.

10.1101/175901 — molecular biology — Posted on 2017-08-14

889 A bestiary of localized sequence rearrangements in human DNA

Frith, M.; Khan, S.

10.1101/175943 — bioinformatics — Posted on 2017-08-14

890 scPipe: a flexible data preprocessing pipeline for single-cell RNA-sequencing data

Tian, L.; Su, S.; Amann-Zalcenstein, D.; Biben, C.; Naik, S. H.; Ritchie, M. E.

10.1101/175927 — bioinformatics — Posted on 2017-08-14

891 Influence of fecal collection conditions and 16S rRNA gene sequencing protocols at two centers on human gut microbiota analysis

Penington, J. S.; Penno, M. A. S.; Ngui, K. M.; Ajami, N. J.; Roth-Schulze, A. J.; Wilcox, S. A.; Bandala-Sanchez, E.; Wentworth, J. M.; Barry, S. C.; Brown, C. Y.; Couper, J. J.; Petrosino, J. F.; Papenfuss, A. T.; Harrison, L. C.; The ENDIA Study Group,

10.1101/175877 — bioinformatics — Posted on 2017-08-14

892 Response to Editas and Intellia: Unexpected mutations after CRISPR-Cas9 editing in vivo

Schaefer, K. A.; Wu, W.-H.; Darbro, B. W.; Colgan, D. F.; Tsang, S. H.; Bassuk, A. G.; Mahajan, V. B.

10.1101/154450 — bioengineering — Posted on 2017-08-13

893 Diverse modes of synaptic signaling, regulation, and plasticity distinguish two classes of C. elegans glutamatergic neurons

Ventimiglia, D.; Bargmann, C.

10.1101/175836 — neuroscience — Posted on 2017-08-13

894 A (blue) light in the dark: Blue light modulates oscillatory alpha activity in the occipital cortex of totally visually blind individuals with intact non-visual photoreception

van Ackeren, M.; Daneault, V.; Hull, J. T.; Albouy, G.; Lepore, F.; Doyon, J.; Czeisler, C. A.; Dumont, M.; Carrier, J.; Lockeley, S. W.; Vandewalle, G.; Collignon, O.

10.1101/175851 — neuroscience — Posted on 2017-08-13

895 De novo mutations involved in post-transcriptional dysregulation contribute to six neuropsychiatric disorders

Mao, F.; Wang, L.; Liu, Q.; Xiao, L.; Li, X.; He, X.; Rao, R. C.; Li, J.; Dou, Y.; Sun, Z.

10.1101/175844 — genomics — Posted on 2017-08-13

896 The evolution of tumour composition during fractionated radiotherapy: implications for outcome

Lewin, T. D.; Maini, P. K.; Moros, E. G.; Enderling, H.; Byrne, H. M.

10.1101/175828 — cancer biology — Posted on 2017-08-13

897 Glucocorticoids and cortical decoding in the phobic brain

Schwab, S.; Federspiel, A.; Morishima, Y.; Nakataki, M.; Strik, W.; Wiest, R.; Heinrichs, M.; de Quervain, D.; Soravia, L. M.

10.1101/099697 — neuroscience — Posted on 2017-08-13

898 Caloric-restriction induced alterations in CG and non-CG methylation attenuate age-associated changes in the old brain.

Hadad, N.; Unnikrishnan, A.; Jackson, J. A.; Masser, D. R.; Otalora, L.; Stanford, D. R.; Richardson, A.; Freeman, W.

10.1101/175810 — neuroscience — Posted on 2017-08-13

899 The complete structure of the small subunit processome

Barandun, J.; Chaker-Margot, M.; Hunziker, M.; Molloy, K. R.; Chait, B. T.; Klinge, S.

10.1101/175547 — biochemistry — Posted on 2017-08-13

900 Population genomics of Wolbachia and mtDNA in Drosophila simulans from California

Signor, S.

10.1101/174375 — evolutionary biology — Posted on 2017-08-13

901 Cysteine Proteases Of Hookworm Necator americanus As Virulence Factors And Implications For Future Drug Design with heparin analogs: A Bioinformatics-Based Study

Banerjee, A.; Abagyan, R.

10.1101/116921 — bioinformatics — Posted on 2017-08-13

902 Making up your mind: Enhanced perceptual decision-making induced by stochastic resonance during non-invasive brain stimulation

van der Groen, O.; Tang, M.; Wenderoth, N.; Mattingley, J.

10.1101/175455 — neuroscience — Posted on 2017-08-13

903 Cellular phenotyping of hippocampal progenitors exposed to patient serum predicts conversion to Alzheimer’s Disease

Maruszak, A.; Murphy, T.; Liu, B.; de Lucia, C.; Douiri, A.; Nevado, A. J.; Teunissen, C. E.; Visser, P. J.; Price, J.; Lovestone, S.; Thuret, S.

10.1101/175604 — neuroscience — Posted on 2017-08-13

904 Pegivirus avoids immune recognition but does not attenuate acute-phase disease in a macaque model of HIV infection

Bailey, A. L.; Buechler, C. R.; Matson, D. R.; Peterson, E. J.; Brunner, K. G.; Mohns, M. S.; Breitbach, M.; Stewart, L. M.; Ericsen, A. J.; Capuano, S.; Simmons, H. A.; Yang, D. T.; O'Connor, D. H.

10.1101/175646 — immunology — Posted on 2017-08-13

905 Cell cycle modulates CXCR4 expression in germinal center B cells

Weber, T. S.

10.1101/175802 — immunology — Posted on 2017-08-13

906 A systems approach to the characterization and classification of T-cell responses

Yamamoto, S.; Whalen, E.; Chujo, D.; Nattamai, D.; Baldwin, N.; O'Brien, K.; Nguyen, Q.-A.; Gersuk, V.; Anguiano, E.; Yang, J.; Kwok, W. W.; Banchereau, J.; Ueno, H.; Chaussabel, D.

10.1101/175620 — genomics — Posted on 2017-08-13

907 Mobility can promote the evolution of cooperation via emergent self-assortment dynamics

Joshi, J.; Couzin, I. D.; Levin, S. A.; Guttal, V.

10.1101/175638 — evolutionary biology — Posted on 2017-08-13

908 Quantitative variation and evolution of spatially explicit morphogen expression in Drosophila

Ali, S.; Signor, S.; Kozlov, K.; Nuzhdin, S.

10.1101/175711 — developmental biology — Posted on 2017-08-13

909 Asymmetric cell volume changes regulate epithelial morphogenesis in zebrafish Kupffers vesicle

Dasgupta, A.; Merkel, M.; Jacob, A. E.; Dawson, J. E.; Amack, J. D.; Manning, L.

10.1101/175679 — cell biology — Posted on 2017-08-13

910 Intraocular pressure elevation precedes a phagocytosis decline in a model of pigmentary glaucoma

Dang, Y.; Waxman, S.; Wang, C.; Loewen, R. T.; Loewen, N. A.

10.1101/175695 — cell biology — Posted on 2017-08-13

911 Pathway-Level Integration of Proteogenomic data in Breast Cancer Using Independent Component Analysis

Liu, W.; Ma, S.; Fenyo, D.

10.1101/175687 — cancer biology — Posted on 2017-08-13

912 Genetic correlations among neuro-behavioral and immune-related phenotypes based on genome-wide association data

Tylee, D. S.; Sun, J.; Hess, J. L.; Tahir, M. A.; Sharma, E.; Malik, R.; Worrall, B. B.; Levine, A. J.; Martinson, J. J.; Nejenstev, S.; Speed, D.; Fischer, A.; Mick, E.; Walker, B. R.; Crawford, A.; Grant, S. F. A.; Polychronakos, C.; Bradfield, J. P.; Sleiman, P. M. A.; Hakonarson, H.; The METASTROKE Consortium of the International Str, ; The Netherlands Twin Registry, ; The neuroCHARGE Working Group, ; The Obsessive Compulsive and Tourette Syndrome Wor, ; Faraone, S. V.; Glatt, S. J.

10.1101/070730 — bioinformatics — Posted on 2017-08-13

913 An Open-Source, Programmable Pneumatic Setup for Operation and Automated Control of Single- and Multi-Layer Microfluidic Devices

Brower, K.; Puccinelli, R.; Markin, C.; Shimko, T.; Longwell, S.; Cruz, B.; Gomez-Sjoberg, R.; Fordyce, P. M.

10.1101/173468 — bioengineering — Posted on 2017-08-13

914 Forecasting crowd dynamics through coarse-grained data analysis

Motsch, S.; Moussaid, M.; Guillot, E. G.; Moreau, M.; Pettre, J.; Theraulaz, G.; Appert-Rolland, C.; Degond, P.

10.1101/175760 — animal behavior and cognition — Posted on 2017-08-13

915 Hybrid approach for parameter estimation in agent-based models

Gallaher, J.; Hawkins-Daarud, A.; Massey, S. C.; Swanson, K.; Anderson, A.

10.1101/175661 — systems biology — Posted on 2017-08-13

916 Computational investigation of biological and technical variability in high throughput phenotyping and cell line identification

Friedman, S. H.; Macklin, P.

10.1101/175703 — cell biology — Posted on 2017-08-13

917 Enhanced proofreading governs CRISPR-Cas9 targeting accuracy

Chen, J. S.; Dagdas, Y. S.; Kleinstiver, B. P.; Welch, M. M.; Harrington, L. B.; Sternberg, S. H.; Joung, J. K.; Yildiz, A.; Doudna, J. A.

10.1101/160036 — biochemistry — Posted on 2017-08-12

918 Dopamine Negatively Modulates the NCA Ion Channels in C. elegans

Topalidou, I.; Cooper, K.; Pereira, L.; Ailion, M.

10.1101/097394 — genetics — Posted on 2017-08-12

919 Assessment of clonal kinetics reveals multiple trajectories of dendritic cell development

Lin, D.; Kan, A.; Gao, J.; Crampin, E.; Hodgkin, P. D.; Naik, S. H.

10.1101/167635 — systems biology — Posted on 2017-08-12

920 Risk factor profile of different clinical manifestations of cerebral small vessel disease - data from SHEF-CSVD Study

Staszewski, J.; Skrobowska, E.; Piusinska-Macoch, R.; Brodacki, B.; Stepien, A.

10.1101/167221 — neuroscience — Posted on 2017-08-12

921 Learning sequence patterns of AGO-sRNA affinity from high-throughput sequencing libraries to improve in silico functional small RNA detection and classification in plants

Morgado, L.; Jansen, R. C.; Johannes, F.

10.1101/173575 — bioinformatics — Posted on 2017-08-12

922 Sensory tuning does not match behavioral relevance of communication signals in free-living weakly electric fish

Henninger, J.; Kirschbaum, F.; Grewe, J.; Krahe, R.; Benda, J.

10.1101/114249 — neuroscience — Posted on 2017-08-12

923 Image Processing and Quality Control for the first 10,000 Brain Imaging Datasets from UK Biobank

Alfaro-Almagro, F.; Jenkinson, M.; Bangerter, N. K.; Andersson, J. L. R.; Griffanti, L.; Douaud, G.; Sotiropoulos, S.; Jbabdi, S.; Hernandez-Fernandez, M.; Vallee, E.; Vidaurre, D.; Webster, M.; McCarthy, P. D.; Rorden, C.; Daducci, A.; Alexander, D.; Zhang, H.; Dragonu, I.; Matthews, P.; Miller, K. L.; Smith, S. M.

10.1101/130385 — neuroscience — Posted on 2017-08-12

924 A descending pathway facilitates undulatory wave propagation in Caenorhabditis elegans through gap junctions

Xu, T.; Huo, J.; Shao, S.; Po, M.; Kawano, T.; Lu, Y.; Wu, M.; Zhen, M.; Wen, Q.

10.1101/131490 — neuroscience — Posted on 2017-08-12

925 Evaluation of in silico algorithms for use with ACMG/AMP clinical variant interpretation guidelines

Ghosh, R.; Oak, N.; Plon, S. E.

10.1101/146100 — bioinformatics — Posted on 2017-08-12

926 The toxic nature of murine amylin and the immune responsivity of pancreatic islet to conformational antibody in mice

Erthal, L. C. S.; Jotha-Mattos, L.; Lara, F. A.; Reis, S. A.; Pascarelli, B. M. O.; Costa, C. M.; Souza, K. L. A.; Lima, L. M. T. R.

10.1101/175539 — biochemistry — Posted on 2017-08-12

927 Alternative REST Splicing Underappreciated

Chen, G.-L.; Miller, G. M.

10.1101/119552 — genomics — Posted on 2017-08-11

928 Worldwide genetic variation of the IGHV and TRBV immune receptor gene families in humans

Luo, S.; Yu, J. A.; Li, H.; Song, Y. S.

10.1101/155440 — genomics — Posted on 2017-08-11

929 Nuclease escape elements protect messenger RNA against cleavage by multiple viral endonucleases

Muller, M.; Glaunsinger, B. A.

10.1101/155457 — molecular biology — Posted on 2017-08-11

930 Proofreading-deficient coronaviruses adapt over long-term passage for increased fidelity and fitness without reversion of exoribonuclease-inactivating mutations

Graepel, K.; Lu, X.; Case, J. B.; Sexton, N. R.; Smith, E. C.; Denison, M. R.

10.1101/175562 — microbiology — Posted on 2017-08-11

931 Bacmeta: simulation for genomic evolution in bacterial metapopulations

Sipola, A.; Marttinen, P.; Corander, J.

10.1101/175257 — genomics — Posted on 2017-08-11

932 A Next Generation Clustering Tool Enables Identification of Functional Cancer Subtypes with Associated Biological Phenotypes

Nyamundanda, G.; Eason, K.; Sadanandam, A.

10.1101/175307 — genomics — Posted on 2017-08-11

933 Extracting a Biologically Relevant Latent Space from Cancer Transcriptomes with Variational Autoencoders

Way, G. P.; Greene, C. S.

10.1101/174474 — bioinformatics — Posted on 2017-08-11

934 Computational pipeline for the PGV-001 neoantigen vaccine trial

Rubinsteyn, A.; Kodysh, J.; Hodes, I.; Mondet, S.; Aksoy, B. A.; Finnigan, J. P.; Bhardwaj, N.; Hammerbacher, J.

10.1101/174516 — bioinformatics — Posted on 2017-08-11

935 Spring flowering habit in field pennycress (Thlaspi arvense) has arisen multiple independent times

Dorn, K. M.; Johnson, E. B.; Daniels, E.; Wyse, D.; Marks, M. D.

10.1101/174920 — plant biology — Posted on 2017-08-11

936 Platelet phosphorylated TDP-43: An exploratory study for a peripheral surrogate biomarker development for Alzheimer’s disease

Wilhite, R.; Sage, J. M.; Bouzid, A.; Primavera, T.; Agbas, A.

10.1101/132837 — neuroscience — Posted on 2017-08-11

937 Sniff invariant odor coding

Shusterman, R.; Sirotin, Y. B.; Smear, M. C.; Ahmadian, Y.; Rinberg, D.

10.1101/174417 — neuroscience — Posted on 2017-08-11

938 The role of a single non-coding nucleotide in the evolution of an epidemic African clade of Salmonella

Hammarlöf, D. L.; Kröger, C.; Owen, S. V.; Canals, R.; Lacharme-Lora, L.; Wenner, N.; Wells, T. J.; Henderson, I. J.; Wigley, P.; Hokamp, K.; Feasey, N. A.; Gordon, M. A.; Hinton, J. C. D.

10.1101/175265 — molecular biology — Posted on 2017-08-11

939 A Supervised Statistical Learning Approach For Accurate Legionella pneumophila Source Attribution During Outbreaks

Buultjens, A.; Chua, K.; Baines, S.; Kwong, J.; Gao, W.; Cutcher, Z.; Adcock, S.; Ballard, S.; Schultz, M. B.; Tomita, T.; Subasinghe, N.; Carter, G.; Pidot, S.; Franklin, L.; Seemann, T.; Goncalves Da Silva, A.; Howden, B.; Stinear, T.

10.1101/133033 — microbiology — Posted on 2017-08-11

940 Spatial and temporal control of norovirus protease activity is determined by polyprotein processing and intermolecular interactions within the viral replication complex.

Emmott, E.; de Rougemont, A.; Haas, J.; Goodfellow, I.

10.1101/175463 — microbiology — Posted on 2017-08-11

941 A family-based method for leveraging random genetic variation to identify variance-controlling loci

Conley, D.; Johnson, R.; Domingue, B. W.; Dawes, C.; Boardman, J.; Siegal, M.

10.1101/175596 — genetics — Posted on 2017-08-11

942 The genetic architecture of the network underlying flowering time variation in Arabidopsis thaliana

Sasaki, E.; Frommlet, F.; Nordborg, M.

10.1101/175430 — genetics — Posted on 2017-08-11

943 Improving on a modal-based estimation method: model averaging for consistent and efficient estimation in Mendelian randomization when a plurality of candidate instruments are valid

Burgess, S.; Zuber, V.; Gkatzionis, A.; Rees, J. M. B.; Foley, C.

10.1101/175372 — genetics — Posted on 2017-08-11

944 Estimation of complex effect-size distributions using summary-level statistics from genome-wide association studies across 32 complex traits and implications for the future

Zhang, Y.; Qi, G.; Park, J.-H.; Chatterjee, N.

10.1101/175406 — genetics — Posted on 2017-08-11

945 Population genomics of Wolbachia and mtDNA in Drosophila simulans from California

Signor, S.

10.1101/174375 — evolutionary biology — Posted on 2017-08-11

946 A scheme for 3-dimensional morphological reconstruction and force inference in the early C. elegans embryo

Xu, M.; Wu, Y.; Shroff, H.; Wu, M.; Mani, M.

10.1101/175166 — biophysics — Posted on 2017-08-11

947 SALMON: inferring protein targets of compounds by network-based analysis of gene transcriptional profiles

Noh, H.; Shoemaker, J. E.; Gunawan, R.

10.1101/175364 — bioinformatics — Posted on 2017-08-11

948 Ubiquitin-related genes are differentially expressed in isogenic lines contrasting for pericarp cell size and grain weight in hexaploid wheat

Brinton, J.; Simmonds, J.; Uauy, C.

10.1101/175471 — plant biology — Posted on 2017-08-11

949 Poly(ADP-ribosyl)ation dependent changes in CTCF-chromatin binding and gene expression in breast cells

Pavlaki, I.; Docquier, F.; Chernukhin, I.; Teif, V. B.; Klenova, E.

10.1101/175448 — molecular biology — Posted on 2017-08-11

950 The exported chaperone PfHsp70x is dispensable for the Plasmodium falciparum intraerythrocytic lifecycle

Cobb, D. W.; Florentin, A.; Fierro, M. A.; Krakowiak, M.; Moore, J. M.; Muralidharan, V.

10.1101/113365 — microbiology — Posted on 2017-08-11

951 Understanding Tissue-specific Gene Regulation

Sonawane, A. R.; Platig, J.; Fagny, M.; Chen, C.-Y.; Paulson, J. N.; Lopes-Ramos, C. M.; DeMeo, D. L.; Quackenbush, J.; Glass, K.; Kuijjer, M. L.

10.1101/110601 — genomics — Posted on 2017-08-11

952 Common variants of NRXN1, LRP1B and RORA are associated with increased ventricular volumes in psychosis - GWAS findings from the B-SNIP deep phenotyping study

10.1101/175489 — genetics — Posted on 2017-08-11

953 X10 Expansion Microscopy Enables 25 nm Resolution on Conventional Microscopes

Truckenbrodt, S.; Maidorn, M.; Crzan, D.; Wildhagen, H.; Kabatas, S.; Rizzoli, S. O.

10.1101/172130 — cell biology — Posted on 2017-08-11

954 A porcine ex vivo model of pigmentary glaucoma

Dang, Y.; Waxman, S.; Wang, C.; Loewen, R. T.; Sun, M.; Loewen, N.

10.1101/118448 — cell biology — Posted on 2017-08-11

955 Chemosensory proteins in the CSP4 clade evolved as plant immunity suppressors before two suborders of plant-feeding hemipteran insects diverged

Drurey, C.; Mathers, T. C.; Prince, D. C.; Wilson, C.; Caceres-Moreno, C.; Mugford, S. T.; Hogenhout, S. A.

10.1101/173278 — evolutionary biology — Posted on 2017-08-11

956 Increased anxiety and decreased sociability in adulthood following paternal deprivation involve oxytocin in the mPFC

He, Z.; Wang, L.; Luo, L.; Jia, R.; Yuan, W.; Hou, W.; Yang, J.; Yang, Y.; Tai, F.

10.1101/175380 — neuroscience — Posted on 2017-08-11

957 Performance-optimized partitioning of clonotypes from high-throughput immunoglobulin repertoire sequencing data

Nouri, N.; Kleinstein, S. H.

10.1101/175315 — immunology — Posted on 2017-08-11

958 SMRT sequencing reveals differential patterns of methylation in two O111:H- Shiga toxigenic Escherichia coli isolates from a historic hemolytic uremic syndrome outbreak in Australia

Forde, B. M.; McAllister, L. J.; Paton, J. C.; Paton, A. W.; Beatson, S.

10.1101/173336 — genomics — Posted on 2017-08-11

959 The genetic architecture of osteoarthritis: insights from UK Biobank

Zengini, E.; Hatzikotoulas, K.; Tachmazidou, I.; Steinberg, J.; Hartwig, F. P.; Southam, L.; Hackinger, S.; Boer, C. G.; Styrkarsdottir, U.; Suveges, D.; Kilian, B.; Gilly, A.; Ingvarsson, T.; Jonsson, H.; Babis, G. C.; McCaskie, A.; Uitterlinden, A. G.; van Meurs, J. B. J.; Thorsteinsdottir, U.; Stefansson, K.; Davey Smith, G.; Wilkinson, J. M.; Zeggini, E.

10.1101/174755 — genetics — Posted on 2017-08-11

960 On the relative role of different age groups during epidemics associated with the respiratory syncytial virus

Goldstein, E.; Nguyen, H. H.; Liu, P.; Viboud, C.; Steiner, C. A.; Worby, C. J.; Lipsitch, M.

10.1101/173351 — epidemiology — Posted on 2017-08-11

961 Identifying factors that may improve mechanistic forecasting models for influenza

Riley, P.; Ben-Nun, M.; Turtle, J. A.; Linker, J.; Bacon, D. P.; Riley, S.

10.1101/172817 — epidemiology — Posted on 2017-08-11

962 Predictors of intestinal inflammation in asymptomatic first-degree relatives of patients with Crohn’s disease

Taylor, K. M.; Hanscombe, K. B.; Iniesta, R.; Traylor, M.; Taylor, N. S.; Powell, N.; Irving, P. M.; Anderson, S. H.; Prescott, N. J.; Mathew, C. G.; Lewis, C. M.; Sanderson, J. D.

10.1101/173492 — epidemiology — Posted on 2017-08-11

963 Multiscale Model Within-host and Between-host for Viral Infectious Diseases

S. Almocera, A. E.; Nguyen, V. K.; Hernandez-Vargas, E. A.

10.1101/174961 — epidemiology — Posted on 2017-08-11

964 Simulation of cancer cell line pharmacogenomics data to optimise experimental design and analysis strategy

Mistry, H.; Chapman, P.

10.1101/174862 — bioinformatics — Posted on 2017-08-11

965 Preservation of three-dimensional spatial structure in the gut microbiome

Hasegawa, Y.; Mark Welch, J. L.; Rossetti, B. J.; Borisy, G. G.

10.1101/175224 — microbiology — Posted on 2017-08-11

Carini, P.; Dupont, C.; Santoro, A. E.

10.1101/175141 — microbiology — Posted on 2017-08-11

967 Chlorinated electron acceptor availability selects for specific Dehalococcoides populations in dechlorinating enrichment cultures and in groundwater

Perez de Mora, A.; Lacourt, A.; McMaster, M. L.; Liang, X.; Dworatzek, S.; Edwards, E. A.

10.1101/175182 — microbiology — Posted on 2017-08-11

968 Quantitative DSB sequencing (qDSB-Seq): a method for genome-wide accurate estimation of absolute DNA double-strand break frequencies per cell

Zhu, Y.; Dojer, N.; Biernacka, A.; Pardo, B.; Forey, R.; Skrzypczak, M.; Fongang, B.; Nde Kengne, J. B.; Yousefi, R.; Pasero, P.; Ginalski, K.; Rowicka, M.

10.1101/171405 — genomics — Posted on 2017-08-11

969 Induction of X-chromosome Inactivation by the Histone Demethylase SMCX/KDM5C

Gayen, S.; Maclary, E.; Murata-Nakamura, Y.; Vallianatos, C. N.; Porter, R. S.; Garay, P. M.; Iwase, S.; Kalantry, S.

10.1101/175174 — genetics — Posted on 2017-08-11

970 Immunologic Effect of Polysaccharides Extracted from Sipunculus nudus (SNP) on Hepatoma HepG2-bearing Mice

Su, J.; Jiang, L.; Wu, J.; Liu, Z.; Wu, Y.

10.1101/175190 — cancer biology — Posted on 2017-08-11

971 Cooperative mechanosensitivity and allostery of focal adhesion clusters

Foo, D. C. W.; Terentjev, E. M.

10.1101/175273 — biophysics — Posted on 2017-08-11

972 FastID: Extremely Fast Forensic DNA Comparisons

Ricke, D. O.

10.1101/173666 — bioinformatics — Posted on 2017-08-11

973 Fast P(RMNE): Fast Forensic DNA Probability of Random Man Not Excluded Calculation

Ricke, D.; Schwartz, S.

10.1101/173708 — bioinformatics — Posted on 2017-08-11

974 GrigoraSNPs: Optimized HTS DNA Forensic SNP Analysis

Ricke, D. O.; Shcherbina, A.; Michaleas, A.; Fremont-Smith, P.

10.1101/173716 — bioinformatics — Posted on 2017-08-11

975 Modeling codon rate variation improves protein positive selection inference and detects nucleotide selection

Davydov, I. I.; Salamin, N.; Robinson-Rechavi, M.

10.1101/174839 — bioinformatics — Posted on 2017-08-11

976 Developing a 3- to 6-state EEG-based brain-computer interface for a robotic manipulator control

Mishchenko, Y.; Kaya, M.; Ozbay, E.; Yanar, H.

10.1101/171025 — bioinformatics — Posted on 2017-08-11

977 Developmental switching in Physarum polycephalum: Petri net analysis of single cell trajectories of gene expression indicates responsiveness and genetic plasticity of the Waddington quasipotential landscape

Werthmann, B.; Marwan, W.

10.1101/151878 — systems biology — Posted on 2017-08-11

978 Allele specific expression and methylation in the bumblebee, Bombus terrestris

Lonsdale, Z. N.; Lee, K. D.; Kyriakidou, M.; Amarasinghe, H. E.; Nathanael, D.; O'Connor, C.; Mallon, E. B.

10.1101/022657 — evolutionary biology — Posted on 2017-08-11

979 Meta-analysis of liver and heart transcriptomic data for functional annotation transfer in mammalian orthologs

Reyes, P. F. L.; Michoel, T.; Joshi, A.; Devailly, G.

10.1101/123414 — bioinformatics — Posted on 2017-08-11

980 Population Genotype Calling from Low-coverage Sequencing Data

Huang, L.; Danecek, P.; Bercovici, S.; Batzoglou, S.

10.1101/085936 — bioinformatics — Posted on 2017-08-11

981 Personal Cancer Genome Reporter: Variant Interpretation Report For Precision Oncology

Nakken, S.; Fournous, G.; Vodak, D.; Aasheim, L. B.; Myklebost, O.; Hovig, E.

10.1101/122366 — bioinformatics — Posted on 2017-08-11

982 Transmission Expression Signature in Nascent Plasmodium vivax Blood Stage Infection

Adapa, S. R.; Taylor, R. A.; Wang, C.; Thomson-Luque, R.; Johnson, L. R.; Jiang, R. H. Y.

10.1101/175018 — systems biology — Posted on 2017-08-11

983 A simple genetic basis of adaptation to a novel thermal environment results in complex metabolic rewiring in Drosophila

Mallard, F.; Nolte, V.; Tobler, R.; Kapun, M.; Schlotterer, C.

10.1101/174011 — evolutionary biology — Posted on 2017-08-11

984 The roles of Conserved Domains in DEMETER-Mediated Active DNA Demethylation in planta

Zhang, C.; Hung, Y.-H.; Zhang, X.-Q.; Zhang, D.; Xiao, W.; Iyer, L. M.; Aravind, L.; Huh, J. H.; Hsieh, T.-F.

10.1101/175091 — plant biology — Posted on 2017-08-10

985 Flavonol rhamnosylation indirectly modifies the cell wall defects of RHAMNOSE BIOSYNTHESIS1 mutants by altering rhamnose flux

Saffer, A.; Irish, V.

10.1101/175133 — plant biology — Posted on 2017-08-10

986 A Global Framework for Estimating Acclimation and Thermal Breadth Predicts Risk from Climate Change

Rohr, J. R.; Civitello, D. J.; Cohen, J. M.; Roznik, E. A.; Sinervo, B.; Dell, A. I.

10.1101/156026 — ecology — Posted on 2017-08-10

987 How Fast Fast-Folding Proteins Fold in Silico

Pang, Y.-P.

10.1101/088849 — biophysics — Posted on 2017-08-10

988 DEsingle: A new method for single-cell differentially expressed genes detection and classification

Miao, Z.; Zhang, X.

10.1101/173997 — bioinformatics — Posted on 2017-08-10

989 Development of Inflammatory Bowel Disease is Linked to a Longitudinal Restructuring of the Gut Metagenome in Mice

Sharpton, T. J.; Lyalina, S.; Luong, J.; Pham, J.; Deal, E. M.; Armour, C.; Gaulke, C.; Sanjabi, S.; Pollard, K. S.

10.1101/173823 — microbiology — Posted on 2017-08-10

990 Evaluating Strategies For Reversing CRISPR-Cas9 Gene Drives

Vella, M. R.; Gunning, C. E.; Lloyd, A. L.; Gould, F.

10.1101/144097 — evolutionary biology — Posted on 2017-08-10

991 Global and Local Dynamics of High-Gamma Activity Underlying Error Processing in the Human Brain Revealed by Noninvasive and Intracranial EEG

Voelker, M.; Fiederer, L. D. J.; Berberich, S.; Hammer, J.; Behncke, J.; Krsek, P.; Tomasek, M.; Marusic, P.; Reinacher, P. C.; Coenen, V. A.; Schulze-Bonhage, A.; Burgard, W.; Ball, T.

10.1101/166280 — neuroscience — Posted on 2017-08-10

992 Natural Language Processing for Classification of Acute, Communicable Findings on Unstructured Head CT Reports: Comparison of Neural Network and Non-Neural Machine Learning Techniques

Chokshi, F.; Shin, B.; Lee, T.; Lemmon, A.; Necessary, S.; Choi, J.

10.1101/173310 — neuroscience — Posted on 2017-08-10

993 Single-molecule assay for proteolytic susceptibility using centrifuge force microscopy:force-induced destabilization of collagen‘s triple helix

Kirkness, M. W. H.; Forde, N. R.

10.1101/171447 — biophysics — Posted on 2017-08-10

994 Spatially varying cis-regulatory divergence in Drosophila embryos elucidates cis-regulatory logic

Combs, P. A.; Fraser, H. B.

10.1101/175059 — systems biology — Posted on 2017-08-10

995 Synthetic protein-sensing riboswitches

Katz, N.; Kaufmann, B.; Cohen, R.; Solomon, O.; Atar, O.; Yakhini, Z.; Goldberg, S.; Amit, R.

10.1101/174888 — synthetic biology — Posted on 2017-08-10

996 Multi-Transition Systems: A theory for neural spatial navigation

Waniek, N.

10.1101/174946 — neuroscience — Posted on 2017-08-10

997 Neural entrainment determines the words we hear

Kosem, A.; Bosker, H. R.; Takashima, A.; Meyer, A.; Jensen, O.; Hagoort, P.

10.1101/175000 — neuroscience — Posted on 2017-08-10

998 Global and Local Dynamics of High-Gamma Activity Underlying Error Processing in the Human Brain Revealed by Noninvasive and Intracranial EEG

Voelker, M.; Fiederer, L. D. J.; Berberich, S.; Hammer, J.; Behncke, J.; Krsek, P.; Tomasek, M.; Marusic, P.; Reinacher, P. C.; Coenen, V. A.; Schulze-Bonhage, A.; Burgard, W.; Ball, T.

10.1101/166280 — neuroscience — Posted on 2017-08-10

999 Humans flexibly incorporate attention-dependent uncertainty into perceptual decisions and confidence

Denison, R. N.; Adler, W. T.; Carrasco, M.; Ma, W. J.

10.1101/175075 — neuroscience — Posted on 2017-08-10

1000 Mitotic chromosomes fold by condensin-dependent helical winding of chromatin loop arrays

Gibcus, J. H.; Samejima, K.; Goloborodko, A.; Samejima, I.; Naumova, N.; Kanemaki, M.; Xie, L.; Paulson, J. R.; Earnshaw, W. C.; Mirny, L. A.; Dekker, J.

10.1101/174649 — genomics — Posted on 2017-08-10

1001 Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line

Nattestad, M.; Goodwin, S.; Ng, K.; Baslan, T.; Sedlazeck, F. J.; Rescheneder, P.; Garvin, T.; Fang, H.; Gurtowski, J.; Hutton, E.; Tseng, E.; Chin, C.-S.; Beck, T.; Sundaravadanam, Y.; Kramer, M.; Antoniou, E.; McPherson, J. D.; Hicks, J.; McCombie, W. R.; Schatz, M. C.

10.1101/174938 — genomics — Posted on 2017-08-10

1002 Deciphering Transcriptional Regulation of Human Core Promoters

Weingarten-Gabbay, S.; Nir, R.; Lubliner, S.; Sharon, E.; Kalma, Y.; Weinberger, A.; Segal, E.

10.1101/174904 — genomics — Posted on 2017-08-10

1003 Assessing eRNAs associated with a cytokine-sensing mammary super-enhancer

Wang, C.; Kuhns, T.; Reinbold, C.; Willi, M.; Hennighausen, L.

10.1101/174953 — genetics — Posted on 2017-08-10

1004 Evolution of Hominin Polyunsaturated Fatty Acid Metabolism: From Africa to the New World

Harris, D. N.; Ruczinski, I.; Yanek, L. R.; Becker, L. C.; Becker, D. M.; Guio, H.; Cui, T.; Chilton, F. H.; Mathias, R. A.; O'Connor, T.

10.1101/175067 — evolutionary biology — Posted on 2017-08-10

1005 Rare earth elements (REE) in freshwater, marine, and terrestrial ecosystems in the eastern Canadian Arctic

MacMillan, G. A.; Chetelat, J.; Heath, J.; Mickpegak, R.; Amyot, M.

10.1101/174870 — ecology — Posted on 2017-08-10

1006 Does genetic risk help to predict amyloid burden in a non-demented population? A Bayesian approach.

Voyle, N.; Jansen, W.; Keohane, A.; Patel, H.; Folarin, A.; Newhouse, S.; Johnston, C.; Lin, K.; Visser, P. J.; Hodges, A.; Dobson, R. J. B.; Kiddle, S.

10.1101/174995 — bioinformatics — Posted on 2017-08-10

1007 Modeling codon rate variation improves protein positive selection inference and detects nucleotide selection

Davydov, I. I.; Salamin, N.; Robinson-Rechavi, M.

10.1101/174839 — bioinformatics — Posted on 2017-08-10

1008 COGEM: A Toolbox for Computational Genomics in Matlab

Perkins, T. J.

10.1101/174896 — bioinformatics — Posted on 2017-08-10

1009 Computational pipeline for the PGV-001 neoantigen vaccine trial

Rubinsteyn, A.; Kodysh, J.; Hodes, I.; Mondet, S.; Aksoy, B. A.; Finnigan, J. P.; Bhardwaj, N.; Hammerbacher, J.

10.1101/174516 — bioinformatics — Posted on 2017-08-10

1010 DEET as a feeding deterrent

Lu, W.; Hwang, J.; Zeng, F.; Leal, W.

10.1101/174979 — animal behavior and cognition — Posted on 2017-08-10

1011 The conflict negativity: Neural correlate of value conflict and indecision during financial decision making

Petersen, G.-K.; Saunders, B.; Inzlicht, M.

10.1101/174136 — neuroscience — Posted on 2017-08-10

1012 Analysis of multistage in vitro fertilization data with mixed multilevel outcomes using joint modelling approaches

Wilkinson, J.; Vail, A.; Roberts, S. A.

10.1101/173534 — epidemiology — Posted on 2017-08-10

1013 Automating Mendelian randomization through machine learning to construct a putative causal map of the human phenome

Hemani, G.; Bowden, J.; Haycock, P. C.; Zheng, J.; Davis, O.; Flach, P.; Gaunt, T. R.; Davey Smith, G.

10.1101/173682 — epidemiology — Posted on 2017-08-10

1014 MERS-CoV spillover at the camel-human interface

Dudas, G.; Carvalho, L.; Rambaut, A.; Bedford, T.

10.1101/173211 — epidemiology — Posted on 2017-08-10

1015 A subset of sweet-sensing neurons identified by IR56d are necessary and sufficient for fatty acid taste

Tauber, J. M.; Brown, E.; Li, Y.; Yurgel, M. E.; Masek, P.; Keene, A. C.

10.1101/174623 — neuroscience — Posted on 2017-08-10

1016 Mouse hue and wavelength-specific luminance contrast sensitivity are non-uniform across visual space

Denman, D. J.; Luviano, J. A.; Ollerenshaw, D. R.; Cross, S.; Williams, D.; Buice, M. A.; Olsen, S. R.; Reid, R. C.

10.1101/174631 — neuroscience — Posted on 2017-08-10

1017 Suppression and facilitation of human neural responses

Schallmo, M.-P.; Kale, A. M.; Millin, R.; Flevaris, A. V.; Brkanac, Z.; Edden, R. A. E.; Bernier, R. A.; Murray, S.

10.1101/174466 — neuroscience — Posted on 2017-08-10

1018 Environmental deformations dynamically shift the spatial metric of the brain

Keinath, A. T.; Epstein, R. A.; Balasubramanian, V.

10.1101/174367 — neuroscience — Posted on 2017-08-10

1019 Exploration and recency as the main proximate causes of probability matching: a reinforcement learning analysis

Feher da Silva, C.; Victorino, C. G.; Caticha, N.; Baldo, M. V. C.

10.1101/104752 — neuroscience — Posted on 2017-08-10

1020 DNA-PK facilitates HIV transcription by regulating the activity of RNA polymerase II and the recruitment of transcription machinery at HIV LTR

Zicari, S.; Sahu, G.; Dubrovsky, L.; Sun, L.; Yue, H.; Jada, T.; Ochem, A.; Bukrinsky, M.; Simon, G.; Tyagi, M.

10.1101/174573 — molecular biology — Posted on 2017-08-10

1021 COMPARISONS OF CODING AND NONCODING SEQUENCES TOINFER THE ORIGIN OF CODON USAGE BIAS

Mainali, P.; Pathak, S.

10.1101/174359 — molecular biology — Posted on 2017-08-10

1022 Permissive zones for the centromere-binding protein ParB on the Caulobacter crescentus chromosome

Tran, N. T.; Stevenson, C. E.; Som, N. F.; Thanapipatsiri, A.; Jalal, A. S. B.; Le, T. B. K.

10.1101/172932 — microbiology — Posted on 2017-08-10

1023 HIV-1 Unspliced RNA Expression Induces Innate Immune Activation in Macrophages

Akiyama, H.; Miller, C. M.; Ettinger, C. R.; Belkina, A. C.; Snyder-Cappione, J.; Gummuluru, S.

10.1101/174508 — microbiology — Posted on 2017-08-10

1024 Integrative analyses of splicing in the aging brain: role in susceptibility to Alzheimer’s Disease

Raj, T.; Li, Y.; Wong, G.; Ramdhani, S.; Wang, Y.-c.; Ng, B.; Wang, M.; Gupta, I.; Haroutunian, V.; Zhang, B.; Schadt, E. E.; Young-Pearse, T.; Mostafavi, S.; Sklar, P.; Bennett, D.; De Jager, P. L.

10.1101/174565 — genomics — Posted on 2017-08-10

1025 Fantastic beasts and how to sequence them: genomic approaches for obscure model organisms.

Matz, M. V.

10.1101/165928 — genomics — Posted on 2017-08-10

1026 Causal Analyses, Statistical Efficiency And Phenotypic Precision Through Recall-By-Genotype Study Design

Corbin, L. J.; Tan, V. Y.; Hughes, D. A.; Wade, K. H.; Paul, D. S.; Tansey, K. E.; Butcher, F.; Dudbridge, F.; Howson, J. M.; Jallow, M. W.; John, C.; Kingston, N.; Lindgren, C. M.; O'Donavan, M.; O'Rahilly, S.; Owen, M. J.; Palmer, C. N. A.; Pearson, E. R.; Scott, R. A.; van Heel, D. A.; Whittaker, J.; Frayling, T.; Tobin, M. D.; Wain, L. V.; Evans, D. M.; Karpe, F.; McCarthy, M. I.; Danesh, J.; Franks, P. W.; Timpson, N. J.

10.1101/124586 — genetics — Posted on 2017-08-10

1027 Genome downsizing, physiological novelty, and the global dominance of flowering plants

Simonin, K. A.; Roddy, A. B.

10.1101/174615 — ecology — Posted on 2017-08-10

1028 BMP signalling is critical for maintaining homeostasis of hair follicles and intestine in adult mice

Nag, A.; Nigam, P.; Narayanan, A. L.; Kumar, M.; Ghosal, R.; Sen, J.; Bandyopadhyay, A.

10.1101/174680 — developmental biology — Posted on 2017-08-10

1029 Committed hemopoietic progenitors, not stem cells, are the principal responders to Hox gene transduction

Lim, H.; Janmohamed, S.; Benveniste, P.; Herrington, R.; Barbara, M.; Frelin, C.; Hyam, D.; Paige, C.; Zuniga-Pflucker, J.-C.; Stocking, C.; Krosl, J.; Sauvageau, G.; Iscove, N.

10.1101/174490 — cell biology — Posted on 2017-08-10

1030 C. elegans HIF-1 is broadly required for survival in hydrogen sulfide

Topalidou, I.; Miller, D. L.

10.1101/174581 — cell biology — Posted on 2017-08-10

1031 Cell growth rate dictates the onset of glass to fluid-like transition and long time super-diffusion in an evolving cell colony

Malmi-Kakkada, A.; Li, X.; Samanta, H. S.; Sinha, S.; Thirumalai, D.

10.1101/174599 — biophysics — Posted on 2017-08-10

1032 Gpufit: An open-source toolkit for GPU-accelerated curve fitting

Przybylski, A.; Thiel, B.; Keller-Findeisen, J.; Stock, B.; Bates, M.

10.1101/174110 — biophysics — Posted on 2017-08-10

1033 Fast, robust and precise 3D localization for arbitrary point spread functions

Li, Y.; Mund, M.; Hoess, P.; Matti, U.; Nijmeijer, B.; Jimenez Sabinina, V.; Ellenberg, J.; Schoen, I.; Ries, J.

10.1101/172643 — biophysics — Posted on 2017-08-10

1034 Theory of reinforcement learning and motivation in the basal ganglia

Bogacz, R.

10.1101/174524 — bioinformatics — Posted on 2017-08-10

1035 Text mining of disease-lifestyle associations to explain comorbidities in electronic health registries

Jensen, L. J.

10.1101/168211 — bioinformatics — Posted on 2017-08-10

1036 Evolution of chalcone isomerase from a non-catalytic ancestor

Kaltenbach, M.; Burke, J. R.; Dindo, M.; Pabis, A.; Munsberg, F. S.; Rabin, A.; Kamerlin, S. C. L.; Noel, J. P.; Tawfik, D. S.

10.1101/174128 — biochemistry — Posted on 2017-08-10

1037 Regressions Fit for Purpose: Models of Locust Phase State Must Not Conflate Morphology With Behaviour

Ott, S. R.

10.1101/174763 — animal behavior and cognition — Posted on 2017-08-10

1038 Maternal RNA-directed DNA methylation is required for seed development in Brassica rapa

Grover, J.; Kendall, T.; Baten, A.; King, G. J.; Mosher, R. A.

10.1101/174805 — plant biology — Posted on 2017-08-10

1039 CART neuropeptide modulates the extended amygdalar CeA-vBNST circuit to gate expression of innate fear

Rale, A.; Shendye, N.; Bodas, D. S.; Subhedar, N.; Ghose, A.

10.1101/096610 — neuroscience — Posted on 2017-08-10

1040 POLD replicates both strands of small kilobase-long replication bubbles initiated at a majority of human replication origins

Artemov, A. V.; Andrianova, M. A.; Bazykin, G. A.; Seplyarskiy, V. B.

10.1101/174730 — molecular biology — Posted on 2017-08-10

1041 CBF-1 promotes the establishment and maintenance of HIV latency by recruiting Polycomb repressive complexes, PRC1 and PRC2, at HIV LTR

Zicari, S.; Farley, K.; Sun, L.; Spurr, L.; Dragon, A.; Bukrinsky, M.; Simon, G.; Chauhan, A.; Tyagi, M.

10.1101/174607 — molecular biology — Posted on 2017-08-10

1042 Newly identified varicella-zoster virus latency transcript inhibits viral replication

Depledge, D. P.; Ouwendijk, W. J. D.; Sadaoka, T.; Braspenning, S. E.; Mori, Y.; Cohrs, R.; Verjans, G.; Breuer, J.

10.1101/174797 — microbiology — Posted on 2017-08-10

1043 Plasticity of the MFS1 promoter leads to multi drug resistance in the wheat pathogen Zymoseptoria tritici

Omrane, S.; Audeon, C.; Ignace, A.; Duplaix, C.; Aouini, L.; Kema, G.; Walker, A.-S.; Fillinger, S.

10.1101/174722 — microbiology — Posted on 2017-08-10

1044 Coherent synthesis of genomic associations with phenotypes and home environments

Lasky, J. R.; Forester, B. R.; Reimherr, M.

10.1101/051110 — genomics — Posted on 2017-08-10

1045 Epigenetic memory via concordant DNA methylation is inversely correlated to developmental potential of mammalian cells

Choi, M.; Genereux, D. P.; Goodson, J.; Al-Azzawi, H.; Allain, S. Q.; Simon, N.; Palasek, S.; Ware, C. B.; Cavanaugh, C.; Miller, D. G.; Johnson, W. C.; Sinclair, K. D.; Stöger, R.; Laird, C. D.

10.1101/072488 — genetics — Posted on 2017-08-10

1046 GHOST: Recovering Historical Signal from Heterotachously-evolved Sequence Alignments

Crotty, S. M.; Minh, B. Q.; Bean, N. G.; Holland, B. R.; Tuke, J.; Jermiin, L. S.; von Haeseler, A.

10.1101/174789 — evolutionary biology — Posted on 2017-08-10

1047 Monsters in the uterus: A parthenogenetic quasi-program causes teratoma-like tumors during aging in wild-type C. elegans

Wang, H.; Zhao, Y.; Ezcurra, M.; Gilliat, A.; Hellberg, J.; Benedetto, A.; Athigapanich, T.; Girstmair, J.; Telford, M.; Zhang, Z.; Gems, D.

10.1101/174771 — developmental biology — Posted on 2017-08-10

1048 Accelerated human liver progenitor generation from pluripotent stem cells by inhibiting formation of unwanted lineages

Ang, L. T.; Tan, A.; Autio, M. I.; Goh, J. S.-h.; Choo, S. H.; Lee, K. L.; Pan, B.; Tan, J.; Lee, J. J. H.; Yeo, I. K. X.; Wong, C. J. Y.; Lum, J. J.; Loh, C. H.; Lim, C. Y. Y.; Oh, J. L. L.; Chia, C. P. L.; Chen, A.; Chen, Q. F.; Weissman, I.; Loh, K. M.; Lim, B.

10.1101/174698 — cell biology — Posted on 2017-08-10

1049 A Linear Algebra Approach to Fast DNA Mixture Analysis Using GPUs

Samsi, S.; Helfer, B.; Kepner, J.; Reuther, A.; Ricke, D. O.

10.1101/174813 — bioinformatics — Posted on 2017-08-10

1050 High resolution annotation of Zebrafish transcriptome using long-read sequencing

Nudelman, G.; Frasca, A.; Kent, B.; Edepli-Sadler, K.; Sealfon, S. C.; Walsh, M. J.; Zaslavsky, E.

10.1101/174821 — bioinformatics — Posted on 2017-08-10

1051 Learning sequence patterns of AGO-sRNA affinity from high-throughput sequencing libraries to improve in silico functional small RNA detection and classification in plants

Morgado, L.; Jansen, R. C.; Johannes, F.

10.1101/173575 — bioinformatics — Posted on 2017-08-10

1052 High-resolution global peptide-protein docking using fragments-based PIPER-FlexPepDock

Alam, N.; Goldstein, O.; Xia, B.; Porter, K. A.; Kozakov, D.; Schueler-Furman, O.

10.1101/174714 — bioinformatics — Posted on 2017-08-10

1053 Identification of functional modules relevant to human neuron maturation and generation of neuron maturity index

He, Z.; Yu, Q.

10.1101/174748 — bioinformatics — Posted on 2017-08-10

1054 PBAF’s genomic binding dynamics are regulated via bromodomain-acetyl-lysine interactions and select chromatin states

Kenworthy, C. A.; Wong, V.; Dziuba, P.; Lavis, L. D.; Liu, W.-L.; Singer, R. H.; Coleman, R. A.

10.1101/111674 — cell biology — Posted on 2017-08-10

1055 Identifying a TFIID interactome via integrated biochemical and high-throughput proteomic studies

Liu, W.-L.; Song, L.; Dailey, G.; Piasecka, A.; Coleman, R. A.

10.1101/111682 — biochemistry — Posted on 2017-08-10

1056 Quantitating Translational Control: mRNA Abundance-Dependent and Independent Contributions and the mRNA Sequences That Specify Them

Li, J. J.; Chew, G.-L.; Biggin, M. D.

10.1101/116913 — genomics — Posted on 2017-08-09

1057 Strategies for analyzing bisulfite sequencing data

Wreczycka, K.; Gosdschan, A.; Yusuf, D.; Gruening, B.; Assenov, Y.; Akalin, A.

10.1101/109512 — bioinformatics — Posted on 2017-08-09

1058 Divergence estimation in the presence of incomplete lineage sorting and migration

Jones, G. R.

10.1101/174342 — evolutionary biology — Posted on 2017-08-09

1059 Efficient parameterization of large-scale mechanistic models enables drug response prediction for cancer cell lines

Froehlich, F.; Kessler, T.; Weindl, D.; Shadrin, A.; Schmiester, L.; Hache, H.; Muradyan, A.; Schuette, M.; Lim, J.-H.; Heinig, M.; Theis, F.; Lehrach, H.; Wierling, C.; Lange, B.; Hasenauer, J.

10.1101/174094 — systems biology — Posted on 2017-08-09

1060 Sniff invariant odor coding

Shusterman, R.; Sirotin, Y. B.; Smear, M. C.; Ahmadian, Y.; Rinberg, D.

10.1101/174417 — neuroscience — Posted on 2017-08-09

1061 The RacGAP βChimaerin is essential for cerebellar granule cell migration

Estep, J. A.; Wong, W.; Wong, Y.-C. E.; Loui, B. M.; Riccomagno, M. M.

10.1101/164897 — neuroscience — Posted on 2017-08-09

1062 Zika virus infection induces synthesis of Digoxin in glioblastoma cells

Lima, E.; Guerreiro, T. M.; Melo, C.; de Oliveira, D. N.; Machado, D.; Lancellotti, M.; Catharino, R.

10.1101/174441 — neuroscience — Posted on 2017-08-09

1063 Natural Language Processing for Classification of Acute, Communicable Findings on Unstructured Head CT Reports: Comparison of Neural Network and Non-Neural Machine Learning Techniques

Chokshi, F.; Shin, B.; Lee, T.; Lemmon, A.; Necessary, S.; Choi, J.

10.1101/173310 — neuroscience — Posted on 2017-08-09

1064 Numerous cultivated and uncultivated viruses encode ribosomal proteins

Mizuno, C. M.; Guyomar, C.; Roux, S.; Lavigne, R.; Rodriguez-Valera, F.; Sullivan, M.; Gillet, R.; Forterre, P.; Krupovic, M.

10.1101/174177 — microbiology — Posted on 2017-08-09

1065 The Past Sure Is Tense: On Interpreting Phylogenetic Divergence Time Estimates

Brown, J. W.; Smith, S. A.

10.1101/113720 — evolutionary biology — Posted on 2017-08-09

1066 Population genomics of Wolbachia and mtDNA in Drosophila simulans from California

Signor, S.

10.1101/174375 — evolutionary biology — Posted on 2017-08-09

1067 Copy-number signatures and mutational processes in ovarian carcinoma

Macintyre, G.; Goranova, T.; De Silva, D.; Ennis, D.; Piskorz, A. M.; Eldridge, M.; Sie, D.; Lewsley, L.-A.; Hanif, A.; Wilson, C.; Dowson, S.; Glasspool, R. M.; Lockley, M.; Brockbank, E.; Montes, A.; Walther, A.; Sundar, S.; Edmondson, R.; Hall, G. D.; Clamp, A.; Gourley, C.; Hall, M.; Fotopoulou, C.; Gabra, H.; Paul, J.; Supernat, A.; Millan, D.; Hoyle, A.; Bryson, G.; Nourse, C.; Mincarelli, L.; Navarro Sanchez, L.; Ylstra, B.; Jimenez-Linan, M.; Moore, L.; Hofmann, O.; Markowetz, F.; McNeish, I. A.; Brenton, J. D.

10.1101/174201 — cancer biology — Posted on 2017-08-09

1068 A catch-bond drives stator mechanosensitivity in the Bacterial Flagellar Motor

Nord, A. L.; Gachon, E.; Perez-Carrasco, R.; Nirody, J. A.; Barducci, A.; Berry, R. M.; Pedaci, F.

10.1101/174292 — biophysics — Posted on 2017-08-09

1069 Experimental and statistical re-evaluation provides no evidence for Drosophila courtship song rhythms

Stern, D.; Clemens, J.; Coen, P.; Calhoun, A.; Hogenesch, J.; Arthur, B.; Murthy, M.

10.1101/140483 — animal behavior and cognition — Posted on 2017-08-09

1070 YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development

Neto, F.; Klaus-Bergmann, A.; Ong, Y.-T.; Alt, S.; Vion, A.-C.; Szymborska, A.; Carvalho, J. R.; Hollfinger, I.; Bartels-Klein, E.; Franco, C. A.; Potente, M.; Gerhardt, H.

10.1101/174185 — developmental biology — Posted on 2017-08-09

1071 Bringing plants and soils to life through a simple role-playing activity

Van Nuland, M. E.; Chen, M.; England, B. J.

10.1101/171009 — scientific communication and education — Posted on 2017-08-09

1072 Science with no fiction: measuring the veracity of scientific reports by citation analysis

Grabitz, P.; Lazebnik, Y.; Nicholson, J.; Rife, S.

10.1101/172940 — scientific communication and education — Posted on 2017-08-09

1073 Predictive representations can link model-based reinforcement learning to model-free mechanisms

Russek, E. M.; Momennejad, I.; Botvinick, M. M.; Gershman, S. J.; Daw, N. D.

10.1101/083857 — neuroscience — Posted on 2017-08-09

1074 Characterization of a replicating mammalian orthoreovirus with tetracysteine tagged μNS for live cell visualization of viral factories

Bussiere, L.; Choudhury, P.; Bellaire, B.; Miller, C. L.

10.1101/174235 — microbiology — Posted on 2017-08-09

1075 MHCflurry: open-source class I MHC binding affinity prediction

O'Donnell, T.; Rubinsteyn, A.; Bonsack, M.; Riemer, A.; Hammerbacher, J.

10.1101/174243 — immunology — Posted on 2017-08-09

1076 Systematic analysis of atx-2 suppressors reveals a novel regulator of PAR-5/14-3-3sigma function during mitosis in Caenorhabditis elegans

Gnazzo, M. M.; Villarreal, A. R.; Skop, A. R.

10.1101/173856 — cell biology — Posted on 2017-08-09

1077 Nitric oxide-dependent inflammation underlies Notch and PI3K/Akt oncogene cooperation

Villegas, S. N.; Gombos, R.; Gutierrez Perez, I.; Garcia Lopez, L.; Garcia-Castillo, J.; Vallejos, D. M.; Da Ros, V.; Mihaly, J.; Dominguez, M.

10.1101/174169 — cancer biology — Posted on 2017-08-09

1078 Rhythms of the Body, Rhythms of the Brain: Respiration, Neural Oscillations, and Embodied Cognition

Varga, S.; Heck, D. H.

10.1101/174276 — animal behavior and cognition — Posted on 2017-08-09

1079 A dual sgRNA approach for functional genomics in Arabidopsis thaliana

Pauwels, L.; De Clercq, R.; Goossens, J.; Inigo, S.; Williams, C.; Ron, M.; Britt, A.; Goossens, A.

10.1101/172676 — plant biology — Posted on 2017-08-09

1080 The conflict negativity: Neural correlate of value conflict and indecision during financial decision making

Petersen, G.-K.; Saunders, B.; Inzlicht, M.

10.1101/174136 — neuroscience — Posted on 2017-08-09

1081 nextPARS: Parallel probing of RNA structures in Illumina

Saus, E.; Willis, J.; Pryszcz, L. P.; Himmelbauer, H.; Gabaldon, T.

10.1101/174144 — genomics — Posted on 2017-08-09

1082 A subgroup of mitochondrial extracellular vesicles discovered in human melanoma tissues are detectable in patient blood

Jang, S. C.; Crescitelli, R.; Cvjetkovic, A.; Belgrano, V.; Bagge, R. O.; Hoog, J. L.; Sundfeldt, K.; Ochiya, T.; Kalluri, R.; Lotvall, J.

10.1101/174193 — cancer biology — Posted on 2017-08-09

1083 The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space

Klughammer, J.; Kiesel, B.; Roetzer, T.; Fortelny, N.; Kuchler, A.; Sheffield, N. C.; Datlinger, P.; Peter, N.; Nenning, K.-H.; Furtner, J.; Nowosielski, M.; Augustin, M.; Mischkulnig, M.; Strobel, T.; Moser, P.; Freyschlag, C. F.; Kerschbaumer, J.; Thome, C.; Grams, A. E.; Stockhammer, G.; Kitzwoegerer, M.; Oberndorfer, S.; Marhold, F.; Weis, S.; Trenkler, J.; Buchroithner, J.; Pichler, J.; Haybaeck, J.; Krassnig, S.; Ali, K. M.; von Campe, G.; Payer, F.; Sherif, C.; Preiser, J.; Hauser, T.; Winkler, P. A.; Kleindienst, W.; Wurtz, F.; Brandner-Kokalj, T.; Stultschnig, M.; Schweiger, S.; Dieck

10.1101/173864 — cancer biology — Posted on 2017-08-09

1084 Autocatalytic microtubule nucleation determines the size and mass of spindles

Decker, F.; Oriola, D.; Dalton, B.; Brugues, J.

10.1101/174078 — biophysics — Posted on 2017-08-09

1085 Labeling RNAs in live cells using malachite green aptamer scaffolds as fluorescent probes

Yerramilli, V. S.; Kim, K. H.

10.1101/173898 — synthetic biology — Posted on 2017-08-09

1086 Context-Dependent Genetic Regulation

Kim, K. H.; Yerramilli, V. S.; Choi, K.; Sauro, H. M.

10.1101/173906 — synthetic biology — Posted on 2017-08-09

1087 Molecular machinery of auxin synthesis, secretion, and perception in the unicellular chlorophyte alga Chlorella sorokiniana UTEX 1230

Khasin, M.; Cahoon, R. R.; Nickerson, K. W.; Riekhof, W. R.

10.1101/172833 — plant biology — Posted on 2017-08-09

1088 Rapid responses of amygdala neurons discriminate facial expressions

Inagaki, M.; Fujita, I.

10.1101/174037 — neuroscience — Posted on 2017-08-09

1089 Cortical processing of breathlessness in the athletic brain

Faull, O. K.; Cox, P. J.; Pattinson, K. T. S.

10.1101/174052 — neuroscience — Posted on 2017-08-09

1090 Note on the power law of forgetting

Kahana, M. J.; Adler, M.

10.1101/173765 — neuroscience — Posted on 2017-08-09

1091 A strain-specific multiplex RT-PCR for Australian rabbit haemorrhagic disease viruses uncovers a new recombinant virus variant in rabbits and hares

Hall, R. N.; Mahar, J. E.; Read, A. J.; Mourant, R.; Piper, M.; Huang, N.; Strive, T.

10.1101/173930 — microbiology — Posted on 2017-08-09

1092 Evolution of exploitative interactions during diversification in Bacillus subtilis biofilms

Dragos, A.; Lakshmanan, N.; Martin, M.; Horvath, B.; Maroti, G.; Falcon Garcia, C.; Lieleg, O.; Kovacs, A. T.

10.1101/173476 — microbiology — Posted on 2017-08-09

1093 Correcting palindromes in long reads after whole-genome amplification

Warris, S.; Schijlen, E.; van de Geest, H.; Vegesna, R.; Hesselink, T.; te Lintel Hekkert, B.; Sanchez-Perez, G.; Medvedev, P.; Makova, K. D.; de Ridder, D.

10.1101/173872 — genomics — Posted on 2017-08-09

1094 Whole exome sequencing of ENU-induced thrombosis modifier mutations in the mouse

Tomberg, K.; Westrick, R.; Kotnik, E.; Siemieniak, D.; Zhu, G.; Saunders, T.; Cleuren, A.; Ginsburg, D.

10.1101/174086 — genetics — Posted on 2017-08-09

1095 Inbred or Outbred? Genetic diversity in laboratory rodent colonies

Brekke, T. D.; Steele, K. A.; Mulley, J. F.

10.1101/174102 — genetics — Posted on 2017-08-09

1096 Centenarian Hotspots in Denmark

Hansen, A. V.; Mortensen, L. H.; Westendorp, R.

10.1101/170654 — epidemiology — Posted on 2017-08-09

1097 Genome-Wide SNPs Reveal the Drivers of Gene Flow In An Urban Population of the Asian Tiger Mosquito, Aedes albopictus

Schmidt, T. L.; Rasic, G.; Zhang, D.; Zheng, X.; Xi, Z.; Hoffmann, A.

10.1101/173963 — ecology — Posted on 2017-08-09

1098 Demogenetic simulations reveal fragmenting effects of climate change on insular lizard populations

Rice, S. E.; Clark, R.

10.1101/173922 — ecology — Posted on 2017-08-09

1099 Pan-embryo cell dynamics of germlayer formation in zebrafish

Shah, G.; Thierbach, K.; Schmid, B.; Reade, A.; Roeder, I.; Scherf, N.; Huisken, J.

10.1101/173583 — developmental biology — Posted on 2017-08-09

1100 A population of adult satellite-like cells in Drosophila is maintained through a switch in RNA-isoforms

Boukhatmi, H.; Bray, S.

10.1101/174151 — developmental biology — Posted on 2017-08-09

1101 Rapid degradation and 3D CLEM of condensin reveal chromatin compaction uncoupled from chromosome architecture in mitosis

Samejima, K.; Booth, D. G.; Ogawa, H.; Paulson, J. R.; Xie, L.; Watson, C. A.; Platani, M.; Kanemaki, M. T.; Earnshaw, W. C.

10.1101/173633 — cell biology — Posted on 2017-08-09

1102 Hundreds of putative non-coding cis-regulatory drivers in chronic lymphocytic leukaemia and skin cancer

Ongen, H.; Delaneau, O.; Stevens, M. W.; Howald, C.; Dermitzakis, E. T.

10.1101/174219 — cancer biology — Posted on 2017-08-09

1103 TF2Network: predicting transcription factor regulators and gene regulatory networks in Arabidopsis using publicly available binding site information

Kulkarni, S. R.; Vaneechoutte, D.; Van de Velde, J.; Vandepoele, K.

10.1101/173559 — bioinformatics — Posted on 2017-08-09

1104 TaxMapper: An Analysis Tool, Reference Database and Workflow for Metatranscriptome Analysis of Eukaryotic Microorganisms

Beisser, D.; Graupner, N.; Grossmann, L.; Timm, H.; Boenigk, J.; Rahmann, S.

10.1101/174227 — bioinformatics — Posted on 2017-08-09

1105 A negative feedback mechanism in the insulin-regulated glucose homeostasis in Japanese flounder Paralichthys olivaceus by two ways of glucose administration

Liu, D.; Han, D.; Guo, B.; Deng, K.; Gu, Z.; Yang, M.; Xu, W.; Zhang, W.; Mai, K.

10.1101/173948 — biochemistry — Posted on 2017-08-09

1106 Asymmetry of an intracellular scaffold at vertebrate electrical synapses

Marsh, A. J.; Michel, J. C.; Adke, A. P.; Heckman, E. L.; Miller, A. C.

10.1101/173955 — neuroscience — Posted on 2017-08-09

1107 A rational theory of set size effects in working memory and attention

van den Berg, R.; Ma, W. J.

10.1101/151365 — neuroscience — Posted on 2017-08-09

1108 Working memory implements distinct maintenance mechanisms depending on task goals

Fahrenfort, J. J.; van Leeuwen, J.; Foster, J.; Awh, E.; Olivers, C. N. L.

10.1101/162537 — neuroscience — Posted on 2017-08-09

1109 Can CRISPR-based gene drive be confined in the wild? A question for molecular and population biology

Marshall, J.; Akbari, O.

10.1101/173914 — genetics — Posted on 2017-08-09

1110 Rescuing Hidden Ecological Data to Tackle Emerging Mosquito-Borne Diseases

Rund, S. S. C.; Martinez, M. E.

10.1101/096875 — ecology — Posted on 2017-08-09

1111 Spatial protein analysis in developing tissues: a sampling-based image processing approach

Leonavicius, K.; Royer, C.; Miranda, A. M. A.; Tyser, R.; Kip, A.; Srinivas, S.

10.1101/163147 — developmental biology — Posted on 2017-08-09

1112 DEsingle: A new method for single-cell differentially expressed genes detection and classification

Miao, Z.; Zhang, X.

10.1101/173997 — bioinformatics — Posted on 2017-08-09

1113 Bystro: Rapid online variant annotation and natural-language filtering at whole-genome scale

Kotlar, A. V.; Trevino, C. E.; Zwick, M. E.; Cutler, D. J.; Wingo, T. S.

10.1101/146514 — bioinformatics — Posted on 2017-08-09

1114 Scanpy for analysis of large-scale single-cell gene expression data

Wolf, F. A.; Angerer, P.; Theis, F. J.

10.1101/174029 — bioinformatics — Posted on 2017-08-09

1115 Human Rab GTPase- and class V myosin-mediated membrane tethering in a chemically defined reconstitution system

Inoshita, M.; Mima, J.

10.1101/129072 — biochemistry — Posted on 2017-08-09

1116 Histopathological image QTL discovery of thyroid autoimmune disease variants

Barry, J. D.; Fagny, M.; Paulson, J. N.; Aerts, H.; Platig, J.; Quackenbush, J.

10.1101/126730 — genomics — Posted on 2017-08-08

1117 Granatum: a graphical single-cell RNA-Seq analysis pipeline for genomics scientists

Zhu, X.; Wolfgruber, T.; Tasato, A.; Garmire, D.; Garmire, L. X.

10.1101/110759 — bioinformatics — Posted on 2017-08-08

1118 Global and local excitation and inhibition shape the dynamics of the cortico-striatal-thalamo-cortical pathway

Radulescu, A. R.; Herron, J.; Kennedy, C.; Scimemi, A.

10.1101/173658 — neuroscience — Posted on 2017-08-08

1119 Advanced whole genome sequencing and analysis of fetal genomes from amniotic fluid

Mao, Q.; Chin, R.; Xie, W.; Deng, Y.; Xu, H.; Zhang, R. Y.; Shi, Q.; Peters, E. E.; Gulbahce, N.; Li, Z.; Chen, F.; Drmanac, R.; Peters, B. A.

10.1101/173807 — genomics — Posted on 2017-08-08

1120 Implications of de novo mutations in guiding drug discovery: A study of four neuropsychiatric disorders

So, H.-C.; Wong, Y.-H.

10.1101/173641 — genomics — Posted on 2017-08-08

1121 Genome size and the extinction of small populations

LaBar, T.; Adami, C.

10.1101/173690 — evolutionary biology — Posted on 2017-08-08

1122 SureMap: Versatile, Error Tolerant, and High Sensitive Read Mapper

Rezaei Seraji, M.; Motahari, S. A.

10.1101/173740 — bioinformatics — Posted on 2017-08-08

1123 Fast P(RMNE): Fast Forensic DNA Probability of Random Man Not Excluded Calculation

Ricke, D.; Schwartz, S.

10.1101/173708 — bioinformatics — Posted on 2017-08-08

1124 Cerebellar Purkinje cell simple spike activity in awake mice represents phase differences between oscillations in medial prefrontal cortex and hippocampus

McAfee, S. S.; Liu, Y.; Sillitoe, R. V.; Heck, D. H.

10.1101/173849 — neuroscience — Posted on 2017-08-08

1125 MEG-BIDS: an extension to the Brain Imaging Data Structure for magnetoencephalography

Niso Galan, J. G.; Gorgolewski, K. J.; Bock, E.; Brooks, T. L.; Flandin, G.; Gramfort, A.; Henson, R. N.; Jas, M.; Litvak, V.; Moreau, J.; Oostenveld, R.; Schoffelen, J.-M.; Tadel, F.; Wexler, J.; Baillet, S.

10.1101/172684 — neuroscience — Posted on 2017-08-08

1126 Development of Inflammatory Bowel Disease is Linked to a Longitudinal Restructuring of the Gut Metagenome in Mice

Sharpton, T.; Lyalina, S.; Loung, J.; Pham, J.; Deal, E. M.; Armour, C.; Gaulke, C.; Sanjabi, S.; Pollard, K. S.

10.1101/173823 — microbiology — Posted on 2017-08-08

1127 Indole-3-Acetaldehyde Dehydrogenase-dependent Auxin Synthesis Contributes to Virulence of Pseudomonas syringae Strain DC3000

McClerklin, S. A.; Lee, S. G.; Nwumeh, R.; Jez, J. M.; Kunkel, B. N.

10.1101/173302 — microbiology — Posted on 2017-08-08

1128 N-methyl-bacillithiol, a new metabolite discovered in the Chlorobiaceae, indicates that bacillithiol and derivatives are widely phylogenetically distributed.

Hiras, J.; Sharma, S. V.; Raman, V.; Tinson, R. A. J.; Arbach, M.; Rodrigues, D. F.; Norambuena, J.; Hamilton, C. J.; Hanson, T. E.

10.1101/173617 — microbiology — Posted on 2017-08-08

1129 Correcting palindromes in long reads after whole-genome amplification

Warris, S.; Schijlen, E.; van de Geest, H.; Vegesna, R.; Hesselink, T.; te Lintel Hekkert, B.; Sanchez-Perez, G.; Medvedev, P.; Makova, K. D.; de Ridder, D.

10.1101/173872 — genomics — Posted on 2017-08-08

1130 Evidence for evolutionary shifts in the fitness landscape of human complex traits

Uricchio, L. H.; Kitano, H. C.; Gusev, A.; Zaitlen, N. A.

10.1101/173815 — evolutionary biology — Posted on 2017-08-08

1131 GrigoraSNPs: Optimized HTS DNA Forensic SNP Analysis

Ricke, D. O.; Shcherbina, A.; Michaleas, A.; Fremont-Smith, P.

10.1101/173716 — bioinformatics — Posted on 2017-08-08

1132 neoantigenR: An annotation based pipeline for tumor neoantigen identification from sequencing data

Tang, S.; Madhavan, S.

10.1101/171843 — bioinformatics — Posted on 2017-08-08

1133 FastID: Extremely Fast Forensic DNA Comparisons

Ricke, D. O.

10.1101/173666 — bioinformatics — Posted on 2017-08-08

1134 Structural basis of the Cope rearrangement and C-C bond-forming cascade in hapalindole/fischerindole biogenesis

Newmister, S. A.; Li, S.; Garcia-Borras, M.; Sanders, J. N.; Yang, S.; Lowell, A. N.; Yu, F.; Smith, J. L.; Williams, R. M.; Houk, K. N.; Sherman, D. H.

10.1101/173674 — biochemistry — Posted on 2017-08-08

1135 A structural and kinetic link between membrane association and amyloid fibril formation of α-Synuclein

Viennet, T.; Wördehoff, M. M.; Uluca, B.; Poojari, C.; Shaykhalishahi, H.; Willbold, D.; Strodel, B.; Heise, H.; Buell, A. K.; Hoyer, W.; Etzkorn, M.

10.1101/173724 — biophysics — Posted on 2017-08-08

1136 Comparative Analysis of Non-linear Behaviour with Power Spectral Intensity Response Between Normal and Epileptic EEG Signals

Ghosh, B.; Sengupta, S.; Nag, S.; Biswas, S.; Sanyal, S.

10.1101/173518 — neuroscience — Posted on 2017-08-08

1137 Olfactory learning primes the heat shock transcription factor HSF-1 to enhance the expression of molecular chaperone genes in C. elegans

Ooi, F. K.; Prahlad, V.

10.1101/152736 — cell biology — Posted on 2017-08-08

1138 Energetics and Conformational Pathways of Functional Rotation in the Multidrug Transporter AcrB

Matsunaga, Y.; Yamane, T.; Terada, T.; Moritsugu, K.; Fujisaki, H.; Murakami, S.; Ikeguchi, M.; Kidera, A.

10.1101/173567 — biophysics — Posted on 2017-08-08

1139 Tau directs intracellular trafficking by regulating the forces exerted by kinesin and dynein teams

Chaudhary, A. R.; Berger, F.; Berger, C. L.; Hendricks, A. G.

10.1101/173609 — biophysics — Posted on 2017-08-08

1140 Abundance-based reconstitution of microbial pan-genomes from whole-metagenome shotgun sequencing data

Plaza Onate, F.; Cervino, A. C. L.; Magoules, F.; Ehrlich, S. D.; Pichaud, M.

10.1101/173203 — bioinformatics — Posted on 2017-08-08

1141 Joint regulation of growth and division timing drives size homeostasis in proliferating animal cells

Singh, A.; Vargas-Garcia, C.; Bjorklund, M.

10.1101/173070 — systems biology — Posted on 2017-08-08

1142 Impaired brain glymphatic flow in a rodent model of chronic liver disease and minimal hepatic encephalopathy

Hadjihambi, A.; Harrison, I.; Arias, N.; Gallego-Duran, R.; Hosford, P. S.; Davies, N.; Habtesion, A.; Lythgoe, M. F.; Gourine, A. V.; Jalan, R.

10.1101/173526 — pathology — Posted on 2017-08-08

1143 Heterogeneities in afferent connectivity dominate local heterogeneities in the emergence of response decorrelation in the dentate gyrus

Mishra, P.; Narayanan, R.

10.1101/173450 — neuroscience — Posted on 2017-08-08

1144 Multimodal Study of Resting-State Functional Connectivity Networks using EEG electrodes position as seed

Rojas, G. M.; Alvarez, C.; Montoya, C.; de la Iglesia-Vaya, M.; Cisternas, J.; Galvez, M.

10.1101/167585 — neuroscience — Posted on 2017-08-08

1145 A spatial memory signal shows that the parietal cortex has access to a craniotopic representation of space

Semework, M.; Steenrod, S. C.; Goldberg, M. E.

10.1101/173245 — neuroscience — Posted on 2017-08-08

1146 Dynamic Phase Synchrony based Ranked Spatio-Temporal Clustering for Tracking Time-Resolved Functional Brain Networks

Aggarwal, P.; Gupta, A.

10.1101/172981 — neuroscience — Posted on 2017-08-08

1147 The fallacy of identification by neutralization in the light of cytopathology nonproducing enterovirus strains

Adewumi, M. O.; Faleye, T. O. C.; Adeniji, J. A.

10.1101/173419 — microbiology — Posted on 2017-08-08

1148 MERS-CoV NSP16 necessary for IFN resistance and viral pathogenesis

Menachery, V. D.; Gralinski, L. E.; Mitchell, H. D.; Dinnon, K. H.; Leist, S. R.; Yount, B. L.; Graham, R. L.; McAnarney, E. T.; Stratton, K. G.; Cockrell, A. S.; Debbink, K.; Sims, A. C.; Waters, K. M.; Baric, R. S.

10.1101/173286 — microbiology — Posted on 2017-08-08

1149 Unexpected mixed-mode transmission and moderate genetic regulation of Symbiodinium communities in a brooding coral

Quigley, K.; Warner, P.; Bay, L.; Willis, B.

10.1101/173591 — microbiology — Posted on 2017-08-08

1150 Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

PGC Bipolar Disorder/Schizophrenia Working Group, ; Ruderfer, D.; Sklar, P.; Kendler, K.

10.1101/173435 — genomics — Posted on 2017-08-08

1151 Genomewide association study identifies 30 loci associated with bipolar disorder

Stahl, E.; Forstner, A.; McQuillin, A.; Ripke, S.; Bipolar Disorder Working Group of the PGC, ; Ophoff, R.; Scott, L.; Cichon, S.; Andreassen, O. A.; Sklar, P.; Kelsoe, J.; Breen, G.

10.1101/173062 — genetics — Posted on 2017-08-08

1152 Compositional heterogeneity and outgroup choice influence the internal phylogeny of the ants

Borowiec, M. L.; Rabeling, C.; Brady, S. G.; Fisher, B. L.; Schultz, T. R.; Ward, P. S.

10.1101/173393 — evolutionary biology — Posted on 2017-08-08

1153 A New Mechanism To Identify Cost Savings in NHS Prescribing: Minimising “Price-Per-Unit”

Croker, R.; Walker, A. J.; Bacon, S.; Curtis, H.; French, L.; Goldacre, B.

10.1101/172569 — epidemiology — Posted on 2017-08-08

1154 Partitioning plant genetic and environmental drivers of above and belowground community assembly

Barbour, M.; Erlandson, S.; Peay, K.; Locke, B.; Jules, E. S.; Crutsinger, G. M.

10.1101/173500 — ecology — Posted on 2017-08-08

1155 Fast, robust and precise 3D localization for arbitrary point spread functions

Li, Y.; Mund, M.; Hoess, P.; Matti, U.; Nijmeijer, B.; Jimenez Sabinina, V.; Ellenberg, J.; Schoen, I.; Ries, J.

10.1101/172643 — biophysics — Posted on 2017-08-08

1156 NeatSeq-Flow: A Lightweight Software for Efficient Execution of High Throughput Sequencing Workflows

Sklarz, M. Y.; Gordon, M.; Chalifa-Caspi, V.

10.1101/173005 — bioinformatics — Posted on 2017-08-08

1157 Recurrent excitation between motoneurones propagates across segments and is purely glutamatergic

Bhumbra, G. S.; Beato, M.

10.1101/160150 — neuroscience — Posted on 2017-08-08

1158 Genomewide association study identifies 30 loci associated with bipolar disorder

Stahl, E.; Forstner, A.; McQuillin, A.; Ripke, S.; Bipolar Disorder Working Group of the PGC, ; Ophoff, R.; Scott, L.; Cichon, S.; Andreassen, O. A.; Sklar, P.; Kelsoe, J.; Breen, G.

10.1101/173062 — genetics — Posted on 2017-08-08

1159 Pan-embryo cell dynamics of germlayer formation in zebrafish

Shah, G.; Thierbach, K.; Schmid, B.; Reade, A.; Roeder, I.; Scherf, N.; Huisken, J.

10.1101/173583 — developmental biology — Posted on 2017-08-08

1160 Prioritizing 2nd and 3rd order interactions via support vector ranking using sensitivity indices on static Wnt measurements

sinha, s.

10.1101/059469 — systems biology — Posted on 2017-08-08

1161 A Neural Mechanism for the Opportunity Cost of Time

Constantino, S. M.; Dalrymple, J.; Gilbert, R. W.; Varenese, S.; Di Rocco, A.; Daw, N.

10.1101/173443 — neuroscience — Posted on 2017-08-08

1162 Interpreting Temporal Fluctuations In Resting-State Functional Connectivity MRI

Liegeois, R.; Laumann, T. O.; Snyder, A. Z.; Zhou, J.; Yeo, B. T. T.

10.1101/135681 — neuroscience — Posted on 2017-08-08

1163 A National Estimate of the Health and Cost Burden of Escherichia coli Bacteraemia in the Hospital Setting: The Importance of Antibiotic Resistance.

Naylor, N. R.; Pouwels, K. B.; Hope, R.; Green, N.; Henderson, K. L.; Knight, G. M.; Atun, R.; Robotham, J. V.; Deeny, S.

10.1101/153775 — epidemiology — Posted on 2017-08-08

1164 Genotypic variability enhances the reproducibility of an ecological study

Milcu, A.; Puga-Freitas, R.; Ellison, A. M.; Blouin, M.; Scheu, S.; Girin, T.; Frechet, G.; Rose, L.; Scherer-Lorenzen, M.; Barot, S.; Lata, J.-C.; Cesarz, S.; Eisenhauer, N.; Gigon, A.; Weigelt, A.; Hansart, A.; Greiner, A.; Pando, A.; Gessler, A.; Grignani, C.; Assandri, D.; Gleixner, G.; Le Galliard, J.-F.; Urban-Mead, K.; Zavattaro, L.; Muller, M. E. H.; Lange, M.; Lukac, M.; Bonkowski, M.; Mannerheim, N.; Buchnann, N.; Butenschoen, O.; Rotter, P.; Seyhun, R.; Devidal, S.; Kayler, Z.; Roy, J.

10.1101/080119 — ecology — Posted on 2017-08-08

1165 Parasympathetic and sympathetic activity are associated with individual differences in neural indices of selective attention in adults

Giuliano, R. J.; Karns, C. M.; Bell, T. A.; Petersen, S.; Skowron, E. A.; Neville, H. J.; Pakulak, E.

10.1101/173377 — neuroscience — Posted on 2017-08-08

1166 Effects of mutation and selection on plasticity of TDH3 promoter activity in Saccharomyces cerevisiae

Duveau, F.; Yuan, D. C.; Metzger, B. P. H.; Hodgins-Davis, A.; Wittkopp, P. J.

10.1101/173344 — genetics — Posted on 2017-08-08

1167 Expanding primary cells from mucoepidermoid and other salivary gland neoplasms for genetic and chemosensitivity testing

Alamri, A. M.; Liu, X.; Blancato, J. K.; Haddad, B. R.; Wang, W.; Zhong, X.; Choudhary, S.; Krawczyk, E.; Kallakury, B. V.; Davidson, B. J.; Furth, P. A.

10.1101/171652 — cancer biology — Posted on 2017-08-08

1168 Functional limb muscle innervation prior to cholinergic transmitter specification during early metamorphosis in Xenopus

Lambert, F. M.; Cardoit, L.; Courty, E.; Bougerol, M.; Thoby-Brisson, M.; Simmers, J.; Tostivint, H.; Le Ray, D.

10.1101/173328 — neuroscience — Posted on 2017-08-08

1169 Role of Immune Checkpoint Proteins in Idiopathic Pulmonary Fibrosis

Habiel, D. M.; Espindola, M.; Kitson, C.; Azzara, A.; Coelho, A. L.; Hogaboam, C. M.

10.1101/173237 — immunology — Posted on 2017-08-08

1170 The crowns have eyes: Multiple opsins found in the eyes of the Crown-of-Thorns Starfish Acanthaster planci

Lowe, E. K.; Garm, A.; Ullrich-Luter, E.; Arnone, M. I.

10.1101/173187 — evolutionary biology — Posted on 2017-08-08

1171 chewBBACA: A complete suite for gene-by-gene schema creation and strain identification

Silva, M.; Machado, M. P.; Rossi, M.; Moran-Gilad, J.; Santos, S.; Ramirez, M.; Carrico, J. A.

10.1101/173146 — bioinformatics — Posted on 2017-08-08

1172 MOSAIC: a chemical-genetic interaction data repository and web resource for exploring chemical modes of action

Nelson, J.; Simpkins, S. W.; Safizadeh, H.; Li, S.; Piotrowski, J.; Hirano, H.; Yashiroda, Y.; Osada, H.; Yoshida, M.; Boone, C.; Myers, C. L.

10.1101/112854 — bioinformatics — Posted on 2017-08-07

1173 Signatures of selection at drug resistance loci in Mycobacterium tuberculosis

Mortimer, T. D.; Weber, A. M.; Pepperell, C. S.

10.1101/173229 — microbiology — Posted on 2017-08-07

1174 Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines

McCauley, S. M.; Kim, K.; Nowosielska, A.; Dauphin, A.; Diehl, W. E.; Luban, J.

10.1101/128447 — microbiology — Posted on 2017-08-07

1175 Gene clusters encoding putative outer membrane electron conduits have specific roles during metal and electrode respiration in Geobacter sulfurreducens

Jimenez Otero, F.; Bond, D. R.

10.1101/169086 — microbiology — Posted on 2017-08-07

1176 dRNA-seq implicates sulfide as master regulator of S(0) metabolism in Chlorobaculum tepidum and other green sulfur bacteria

Hilzinger, J. M.; Raman, V.; Shuman, K. E.; Eddie, B. J.; Hanson, T. E.

10.1101/172254 — microbiology — Posted on 2017-08-07

1177 Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

Duffy, D.; Zhu, G.; Li, X.; Sanna, M.; Iles, M.; Jacobs, L. C.; Evans, D. M.; Yazar, S.; Beesley, J.; Law, M.; Kraft, P.; Visconti, A.; Taylor, J. C.; Liu, F.; Wright, M. J.; Henders, A. K.; Bowdler, L.; Glass, D.; Ikram, A. M.; Uitterlinden, A. G.; Madden, P. A.; Heath, A. C.; Nelson, E. C.; Green, A. C.; Chanock, S.; Barrett, J. H.; Brown, M. A.; Hayward, N. K.; MacGregor, S.; Sturm, R. A.; Hewitt, A. W.; Melanoma GWAS Consortium, ; Kayser, M.; Hunter, D. J.; Newton Bishop, J. A.; Spector, T. D.; Montgomery, G. W.; Mackey, D. A.; Smith, G. D.; Nijsten, T. E.; Bishop, D. T.; Bataille, V.; Fa

10.1101/173112 — genetics — Posted on 2017-08-07

1178 Genomewide association study identifies 30 loci associated with bipolar disorder

Stahl, E.; Forstner, A.; McQuillin, A.; Ripke, S.; Ophoff, R.; Scott, L.; Cichon, S.; Andreassen, O. A.; Sklar, P.; Kelsoe, J.; Breen, G.

10.1101/173062 — genetics — Posted on 2017-08-07

1179 TraPS-VarI: a python module for the identification of STAT3 modulating germline receptor variants

Kogan, D.; Ulaganathan, V. K.

10.1101/173047 — bioinformatics — Posted on 2017-08-07

1180 Juvenile Hormone, But Not Nutrition Or Social Cues, Affects Reproductive Maturation In Solitary Alkali Bees (Nomia melanderi)

Kapheim, K. M.; Johnson, M. M.

10.1101/134387 — physiology — Posted on 2017-08-07

1181 Saccharomyces cerevisiae strain YH166: a novel wild yeast for the production of tropical fruit sensory attributes in fermented beverages

Osburn, K.; Caputo, R.; Miller, J.; Bochman, M. L.

10.1101/149732 — microbiology — Posted on 2017-08-07

1182 Asleep at the Wheel: Forward Genetic ENU Mutagenesis Screen for Mouse Models of Chronic Fatigue Identifies a Mutation in Slc2a4 (GLUT4)

de Groot, M. H. M.; Castorena, C. M.; Kumar, V.; Mohawk, J. A.; Ahmed, N. I.; Takahashi, J. S.

10.1101/163378 — genetics — Posted on 2017-08-07

1183 BLM helicase suppresses recombination at G-quadruplex motifs in transcribed genes

van Wietmarschen, N.; Merzouk, S.; Halsema, N.; Spierings, D. C. J.; Guryev, V.; Lansdorp, P. M.

10.1101/173252 — cell biology — Posted on 2017-08-07

1184 iSUMO - integrative prediction of functionally relevant SUMOylation events

Yao, X.; Maity, S.; Gandhi, S.; Imielinski, M.; Vogel, C.

10.1101/056564 — systems biology — Posted on 2017-08-07

1185 Beyond the labeled line: variation in visual reference frames from intraparietal cortex to frontal eye fields and the superior colliculus

Caruso, V. C.; Pages, D. S.; Sommer, M.; Groh, J. M.

10.1101/124628 — neuroscience — Posted on 2017-08-07

1186 Random Sequences Rapidly Evolve Into De Novo Promoters

Yona, A. H.; Alm, E. J.; Gore, J.

10.1101/111880 — evolutionary biology — Posted on 2017-08-07

1187 Structural Basis of Mitochondrial Receptor Binding and GTP Driven Conformational Constriction by Dynamin-Related Protein 1

Kalia, R.; Wang, R. Y.- R.; Yusuf, A.; Thomas, P. V.; Agard, D. A.; Shaw, J. M.; Frost, A.

10.1101/172809 — biophysics — Posted on 2017-08-07

1188 The Reproducibility Of Research And The Misinterpretation Of P Values

Colquhoun, D.

10.1101/144337 — scientific communication and education — Posted on 2017-08-07

1189 Recurrent convolutional neural networks: a better model of biological object recognition

Spoerer, C. J.; McClure, P.; Kriegeskorte, N.

10.1101/133330 — neuroscience — Posted on 2017-08-07

1190 Catecholamines, not acetylcholine, alter cortical and perceptual dynamics in line with increased excitation-inhibition ratio

Pfeffer, T.; Avramiea, A.-E.; Nolte, G.; Engel, A. K.; Linkenkaer-Hansen, K.; Donner, T. H.

10.1101/170613 — neuroscience — Posted on 2017-08-07

1191 rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline

Jain, D.; Meydan, C.; Lange, J.; Claeys Bouuaert, C.; Mason, C. E.; Anderson, K. V.; Keeney, S.

10.1101/121822 — genetics — Posted on 2017-08-07

1192 Reverse-Correlation Analysis of Mechanosensation Circuit in C. elegans Reveals Temporal and Spatial Encoding

Porto, D. A.; Giblin, J.; Zhao, Y.; Lu, H.

10.1101/147363 — bioengineering — Posted on 2017-08-07

1193 Gossypol biosynthesis in cotton revealed through organ culture, plant grafting and gene expression profiling

Tianlun, Z.; Jiahui, H.; Cheng, L.; Cong, L.; Lei, M.; Jinhong, C.; Shuijin, Z.

10.1101/173138 — synthetic biology — Posted on 2017-08-07

1194 Euclidean distance as a measure to distinguish ventral and dorsal white matter connectivity in the human brain

Kellmeyer, P.; Vry, M.-S.

10.1101/053959 — neuroscience — Posted on 2017-08-07

1195 GABAergic inhibition of leg motoneurons is required for normal walking behavior in freely moving Drosophila

Gowda, S. B. M.; Paranjpe, P. D.; Reddy, O. V.; Palliyil, S.; Reichert, H.; VijayRaghavan, K.

10.1101/173120 — neuroscience — Posted on 2017-08-07

1196 Intrauterine position probabilities in mice, rats and gerbils

Mulley, J. F.; Kuncheva, L. I.

10.1101/173153 — developmental biology — Posted on 2017-08-07

1197 Cpk2, a catalytic subunit of cyclic AMP-PKA, regulates growth and pathogenesis in rice blast

Selvaraj, P.; Shen, Q.; Fan, Y.; Naqvi, N. I.

10.1101/173104 — cell biology — Posted on 2017-08-07

1198 Deubiquitylation and stabilization of p21 by USP11 is critical for cell cycle progression and DNA damage responses

Deng, T.; Yan, G.; Zhou, Y.; Hu, X.; Li, J.; Hu, J.; Zhang, H.; Feng, P.; Sheng, X.; Chen, J.; Ma, H.; Sun, Y.; Wei, D.; Hu, B.; Liu, J.; Tan, W.; Ye, M.

10.1101/172999 — cell biology — Posted on 2017-08-07

1199 De Novo Prediction of Human Chromosome Structures: Epigenetic Marking Patterns Encode Genome Architecture

Di Pierro, M.; Cheng, R. R.; Lieberman Aiden, E.; Wolynes, P. G.; Onuchic, J. N.

10.1101/173088 — biophysics — Posted on 2017-08-07

1200 TraPS-VarI: a python module for the identification of STAT3 modulating germline receptor variants

Kogan, D.; Ulaganathan, V. K.

10.1101/173047 — bioinformatics — Posted on 2017-08-07

1201 De novo draft assembly of the Botrylloides leachii genome provides further insight into tunicate evolution.

Blanchoud, S.; Rutherford, K.; Zondag, L.; Gemmell, N.; Wilson, M. J.

10.1101/152983 — genomics — Posted on 2017-08-06

1202 Response of oriental xerophytes to the occidental industrial revolution

Manafzadeh, S.; Staedler, Y. M.; Moazzeni, H.; Masson, D.; Schoenenberger, J.; Conti, E.

10.1101/173013 — plant biology — Posted on 2017-08-06

1203 Human hippocampal replay during rest prioritizes weakly-learned information and predicts memory performance

Schapiro, A. C.; McDevitt, E. A.; Rogers, T. T.; Mednick, S. C.; Norman, K. A.

10.1101/173021 — neuroscience — Posted on 2017-08-06

1204 Fear extinction requires infralimbic cortex projections to the basolateral amygdala

Bloodgood, D. W.; Sugam, J. A.; Holmes, A.; Kash, T. L.

10.1101/172791 — neuroscience — Posted on 2017-08-06

1205 A genetic screen suggests an alternative mechanism for inhibition of SecA by azide

Jamshad, M.; Chandler, R.; Jeeves, M.; Robinson, A.; Alam, F.; Cranford Smith, T.; Shah, A.; Daubney, O. J.; Dunne, K.; Nabi, N.; Iqbal, A.; Peacock, A. F. A.; Lovett, J. E.; Knowles, T.; Henderson, I. R.; Huber, D.

10.1101/173039 — microbiology — Posted on 2017-08-06

1206 Improving the quality of combined EEG-TMS neural recordings: Introducing the Coil Spacer

Ruddy, K. L.; Woolley, D. G.; Mantini, D.; Balsters, J.; Wenderoth, N.

10.1101/170431 — neuroscience — Posted on 2017-08-06

1207 Dorsal Anterior Cingulate-Midbrain Ensemble As A Reinforcement Meta-Learner

Silvetti, M.; Vassena, E.; Abrahamse, E.; Verguts, T.

10.1101/130195 — neuroscience — Posted on 2017-08-06

1208 Safety and Lack of Negative Effects of Wearable Augmented-Reality Social Communication Aid for Children and Adults with Autism

Sahin, N. T.; Keshav, N. U.; Salisbury, J. P.; Vahabzadeh, A.

10.1101/164335 — neuroscience — Posted on 2017-08-06

1209 Cool Enough for School: Second Version of Google Glass Rated by Children Facing Challenges to Social Integration as Desirable to Wear at School

Sahin, N. T.; Keshav, N. U.; Salisbury, J. P.; Vahabzadeh, A.

10.1101/171033 — neuroscience — Posted on 2017-08-06

1210 Selection On Morphological Traits And Fluctuating Asymmetry By A Fungal Parasite In The Yellow Dung Fly

Blanckenhorn, W. U.

10.1101/136325 — evolutionary biology — Posted on 2017-08-06

1211 Histone H4 acetylation regulates behavioral inter-individual variability in zebrafish

Roman, A.-C.; Vicente-Page, J.; Perez-Escudero, A.; Carvajal-Gonzalez, J. M.; Fernandez-Salguero, P. M.; de Polavieja, G. G.

10.1101/100230 — animal behavior and cognition — Posted on 2017-08-06

1212 geneXtendeR: optimized functional annotation of ChIP-seq data

Khomtchouk, B. B.; Van Booven, D.; Wahlestedt, C.

10.1101/082347 — bioinformatics — Posted on 2017-08-06

1213 DeepATAC: A deep-learning method to predict regulatory factor binding activity from ATAC-seq signals

Hiranuma, N.; Lundberg, S.; Lee, S.-I.

10.1101/172767 — bioinformatics — Posted on 2017-08-06

1214 Replicability of time-varying connectivity patterns in large resting state fMRI samples

Abrol, A.; Damaraju, E.; Miller, R. L.; Stephen, J. M.; Claus, E. D.; Mayer, A. R.; Calhoun, V. D.

10.1101/172866 — neuroscience — Posted on 2017-08-06

1215 ketu mutant mice uncover an essential meiotic function for the ancient, putative RNA helicase YTHDC2

Jain, D.; Puno, M. R.; Anderson, K. V.; Keeney, S.

10.1101/171827 — genetics — Posted on 2017-08-06

1216 Multi-allelic Exact tests for Hardy-Weinberg equilibrium that account for gender

Graffelman, J.; Weir, B.

10.1101/172874 — genetics — Posted on 2017-08-06

1217 Archaeogenetics of Late Iron Age Cemialo Sırtı, Batman: Investigating maternal genetic continuity in North Mesopotamia since the Neolithic

Yaka, R.; Birand, A.; Yılmaz, Y.; Caner, C.; Acan, S. C.; Gündüzalp, S.; Parvizi, P.; Erim Özdogan, A.; Togan, Z. I.; Somel, M.

10.1101/172890 — evolutionary biology — Posted on 2017-08-06

1218 Microbial mutualism at a distance

Peaudecerf, F. J.; Bunbury, F.; Bhardwaj, V.; Bees, M. A.; Smith, A. G.; Goldstein, R. E.; Croze, O. A.

10.1101/172924 — biophysics — Posted on 2017-08-06

1219 MentaLiST - A fast MLST caller for large wgMLST schemes

Feijao, P.; Yao, H.-T.; Fornika, D.; Gardy, J.; Hsiao, W.; Chauve, C.; Chindelevitch, L.

10.1101/172858 — bioinformatics — Posted on 2017-08-06

1220 Anti-diabetic drug binding site in KATP channels revealed by Cryo-EM

Martin, G. M.; Kandasamy, B.; DiMaio, F.; Yoshioka, C.; Shyng, S.-L.

10.1101/172908 — biochemistry — Posted on 2017-08-05

1221 Anisotropic Cellular Mechanoresponse for Radial Size Maintenance of Developing Epithelial Tubes

Hirashima, T.; Adachi, T.

10.1101/172916 — bioinformatics — Posted on 2017-08-05

1222 Anti-diabetic drug binding site in KATP channels revealed by Cryo-EM

Martin, G. M.; Yoshioka, C.; Kandasamy, B.; DiMaio, F.; Shyng, S.-L.

10.1101/172908 — biochemistry — Posted on 2017-08-05

1223 Understanding the dynamics of scaffold-mediated signaling

Suderman, R.; Schauer, A.; Deeds, E.

10.1101/167205 — systems biology — Posted on 2017-08-05

1224 Interplay between mitochondria and diet mediates pathogen and stress resistance in C. elegans

Revtovich, A.; Lee, R.; Kirienko, N.

10.1101/154393 — molecular biology — Posted on 2017-08-05

1225 Climate change drives uncertain global shifts in potential distribution and seasonal risk of Aedes-transmitted viruses

Ryan, S. J.; Carlson, C. J.; Mordecai, E. A.; Johnson, L. R.

10.1101/172221 — epidemiology — Posted on 2017-08-05

1226 CBFβ initiates the hematopoietic stem cell program without obligatory binding to RUNX

Ciau-Uitz, A.; Pinheiro, P.; Kirmizitas, A.; Fernandez, C.; Patient, R.

10.1101/172957 — developmental biology — Posted on 2017-08-05

1227 Ethoscopes: An Open Platform For High-Throughput Ethomics

Geissmann, Q.; Garcia Rodriguez, L.; Beckwith, E. J.; French, A. S.; Jamasb, A. R.; Gilestro, G. F.

10.1101/113647 — animal behavior and cognition — Posted on 2017-08-05

1228 iSUMO - integrative prediction of functionally relevant SUMOylation events

Yao, X.; Maity, S.; Gandhi, S.; Imielenski, M.; Vogel, C.

10.1101/056564 — systems biology — Posted on 2017-08-05

1229 Evolution of the sex ratio and effective number under gynodioecy and androdioecy

Uyenoyama, M. K.; Takebayashi, N.

10.1101/113605 — evolutionary biology — Posted on 2017-08-05

1230 DNA Damage Checkpoint Dynamics Drive Cell Cycle Phase Transitions

Chao, H. X.; Poovey, C. E.; Privette, A. A.; Grant, G. D.; Cook, J. G.; Chao, H. Y.; Purvis, J. E.

10.1101/137307 — systems biology — Posted on 2017-08-04

1231 But will they even wear it? Exploring the tolerability of social communication coaching smartglasses in children and adults with autism.

Keshav, N. U.; Salisbury, J. P.; Vahabzadeh, A.; Sahin, N. T.

10.1101/164376 — neuroscience — Posted on 2017-08-04

1232 Preliminary Report on the Impact of Smartglasses-based Behavioral and Social Communication Aid on Hyperactivity in Children and Adults with Autism.

Vahabzadeh, A.; Keshav, N. U.; Salisbury, J. P.; Sahin, N. T.

10.1101/165514 — neuroscience — Posted on 2017-08-04

1233 Cool Enough for School: Second Version of Google Glass Rated by Children Facing Challenges to Social Integration as Desirable to Wear at School

Sahin, N. T.; Keshav, N. U.; Salisbury, J. P.; Vahabzadeh, A.

10.1101/171033 — neuroscience — Posted on 2017-08-04

1234 Safety and Lack of Negative Effects of Wearable Augmented-Reality Social Communication Aid for Children and Adults with Autism

Sahin, N. T.; Keshav, N. U.; Salisbury, J. P.; Vahabzadeh, A.

10.1101/164335 — neuroscience — Posted on 2017-08-04

1235 Adaptive potential of a drug-targeted viral protein as a function of positive selection

Dai, L.; Du, Y.; Qi, H.; Wu, N. C.; Wang, E.; Lloyd-Smith, J. O.; Sun, R.

10.1101/078428 — evolutionary biology — Posted on 2017-08-04

1236 Evolution of steroid specificity in human, chicken, alligator, frog and zebrafish mineralocorticoid receptors: Allosteric interactions affect steroid specificity

Katsu, Y.; Oka, K.; Baker, M. E.

10.1101/151233 — evolutionary biology — Posted on 2017-08-04

1237 A Liquid Chromatography-Mass Spectrometry Method For Screening Disulfide Tethering Fragments

Hallenbeck, K. K.; Davies, J.; Merron, C.; Ogden, P.; Sijbesma, E.; Ottmann, C.; Renslo, A. R.; Wilson, C.; Arkin, M. R.

10.1101/138941 — biophysics — Posted on 2017-08-04

1238 Cortical interneurons ensure maintenance of frequency tuning following adaptation.

Natan, R. G.; Rao, W.; Geffen, M. N.

10.1101/172338 — neuroscience — Posted on 2017-08-04

1239 Very high density EEG elucidates spatiotemporal aspects of early visual processing

Robinson, A. K.; Venkatesh, P.; Boring, M. J.; Tarr, M. J.; Grover, P.; Behrmann, M.

10.1101/172353 — neuroscience — Posted on 2017-08-04

1240 Repeated vapor inhalation of Δ9-tetrahydrocannabinol induces tolerance to hypothermia in female rats

Nguyen, J.; Creehan, K.; Grant, Y.; Vandewater, S.; Cole, M.; Taffe, M. A.

10.1101/172759 — neuroscience — Posted on 2017-08-04

1241 A functioning model of human time perception

Roseboom, W.; Fountas, Z.; Nikiforou, K.; Bhowmik, D.; Shanahan, M.; Seth, A. K.

10.1101/172387 — neuroscience — Posted on 2017-08-04

1242 Modulation of host learning in Aedes aegypti mosquitoes

Vinauger, C.; Lahondere, C.; Wolff, G.; Locke, L.; Liaw, J.; Parrish, J.; Akbari, O.; Dickinson, M.; Riffell, J.

10.1101/172726 — neuroscience — Posted on 2017-08-04

1243 Mouse MRI shows brain areas larger in males emerge earlier than those larger in females

Qiu, L. R.; Fernandes, D. J.; Szulc, K. U.; Dazai, J.; Nieman, B. J.; Turnbull, D. H.; Palmert, M. R.; Lerch, J. P.

10.1101/172841 — neuroscience — Posted on 2017-08-04

1244 NmeCas9 is an intrinsically high-fidelity genome editing platform

Amrani, N.; Gao, X. D.; Liu, P.; Gupta, A.; Edraki, A.; Ibraheim, R.; Sasaki, K. E.; Zhu, L. J.; Wolfe, S. A.; Sontheimer, E. J.

10.1101/172650 — molecular biology — Posted on 2017-08-04

1245 Geobacter sulfurreducens extracellular multiheme cytochrome PgcA facilitates respiration to Fe(III) oxides but not electrodes

Zacharoff, L. A.; Morrone, D.; Bond, D. R.

10.1101/172775 — microbiology — Posted on 2017-08-04

1246 T-cell receptor sequencing of early stage breast cancer tumors identifies altered clonal structure of the T-cell repertoire

Beausang, J. F.; Wheeler, A. J.; Chan, N. H.; Hanft, V. R.; Dirbas, F. M.; Jeffrey, S. S.; Quake, S. R.

10.1101/172494 — immunology — Posted on 2017-08-04

1247 In situ genome editing method suitable for routine generation of germline modified animal models

Ohtsuka, M.; Miura, H.; Arifin, N.; Nakamura, S.; Wada, K.; Gurumurthy, C.; Sato, M.

10.1101/172718 — genomics — Posted on 2017-08-04

1248 Capture-based DNA methylation sequencing facilitates diagnosis and reveals potential pathogenic mechanisms in teratogenic diabetes exposure

Schulze, K. V.; Bhatt, A.; Azamian, M. S.; Sundgren, N. C.; Zapata, G.; Hernandez, P.; Fox, K.; Kaiser, J. R.; Belmont, J. W.; Hanchard, N. A.

10.1101/172262 — genetics — Posted on 2017-08-04

1249 Nonconsumptive predator effects on prey demography: Dogwhelk cues decrease benthic mussel recruitment

Ehlers, S. M.; Scrosati, R. A.; Ellrich, J. A.

10.1101/172692 — ecology — Posted on 2017-08-04

1250 Structural Basis of Mitochondrial Receptor Binding and GTP Driven Conformational Constriction by Dynamin-Related Protein 1

Kalia, R.; Wang, R. Y.- R.; Yusuf, A.; Thomas, P. V.; Agard, D. A.; Shaw, J. M.; Frost, A.

10.1101/172809 — biophysics — Posted on 2017-08-04

1251 GTP Hydrolysis by eIF5B in the Last Step of Translation Initiation Is Activated by a Rotation of the Small Ribosomal Subunit.

Fernandez, I. S.; Ramakrishnan, V.

10.1101/172825 — biochemistry — Posted on 2017-08-04

1252 The RNA-binding site of poliovirus 3C protein doubles as a phosphoinositide-binding domain

Shengjuler, D.; Chan, Y. M.; Sun, S.; Moustafa, I. M.; Li, Z.-L.; Gohara, D. W.; Buck, M.; Cremer, P. S.; Boehr, D. D.; Cameron, C. E.

10.1101/172742 — biochemistry — Posted on 2017-08-04

1253 Resources For Interpreting Variants In Precision Genomic Oncology Applications

Tsang, H.; Addepalli, K.; Davis, S. R.

10.1101/144766 — bioinformatics — Posted on 2017-08-04

1254 Integrator Subunit 4 is a ‘Symplekin-like’ Scaffold that Associates with INTS9/11 to Form the Integrator Cleavage Module

Albrecht, T. R.; Shevtsov, S. P.; Mascibroda, L. G.; Peart, N. J.; Sawyer, I. A.; Dundr, M.; Wagner, E. J.

10.1101/172635 — molecular biology — Posted on 2017-08-04

1255 Estimating Autoantibody Signatures To Detect Autoimmune Disease Patient Subsets

Wu, Z.; Casciola-Rosen, L.; Shah, A. A.; Rosen, A.; Zeger, S. L.

10.1101/128199 — immunology — Posted on 2017-08-04

1256 Climate change drives uncertain global shifts in potential distribution and seasonal risk of Aedes-transmitted viruses

Ryan, S. J.; Carlson, C. J.; Mordecai, E. A.; Johnson, L. R.

10.1101/172221 — epidemiology — Posted on 2017-08-04

1257 Whole chromosome loss in tetraploid cells confers tumorigenic potential in a mouse allograft model

Thomas, R.; Marks, D. H.; Chin, Y.; Benezra, R.

10.1101/172668 — cancer biology — Posted on 2017-08-04

1258 Integrative DNA copy number detection and genotyping from sequencing and array-based platforms

Zhou, Z.; Wang, W.; Wang, L.-S.; Zhang, N.

10.1101/172700 — bioinformatics — Posted on 2017-08-04

1259 HiCRep: assessing the reproducibility of Hi-C data using a stratum-adjusted correlation coefficient

Yang, T.; Zhang, F.; Yardimci, G. G.; Song, F.; Hardison, R. C.; Noble, W. S.; Yue, F.; Li, Q.

10.1101/101386 — bioinformatics — Posted on 2017-08-04

1260 Drosophila Mutants that Are Motile but Respond Poorly to All Stimuli Tested

Vang, L. L.; Adler, J.

10.1101/066423 — animal behavior and cognition — Posted on 2017-08-04

1261 From brain noise to syntactic structures: A formal proposal within the oscillatory rhythms perspective

Grimaldi, M.

10.1101/171702 — neuroscience — Posted on 2017-08-04

1262 Intercellular communication via the comX-Inducing Peptide (XIP) of Streptococcus mutans

Kaspar, J.; Underhill, S. A. M.; Shields, R. C.; Reyes, A.; Rosenzweig, S.; Hagen, S. J.; Burne, R. A.

10.1101/148320 — microbiology — Posted on 2017-08-04

1263 Long non-coding RNA repertoire and regulation by nuclear exosome, cytoplasmic exonuclease and RNAi in fission yeast

Atkinson, S. R.; Marguerat, S.; Bitton, D. A.; Rodriguez-Lopez, M.; Rallis, C.; Lemay, J.-F.; Cotobal, C.; Malecki, M.; Mata, J.; Bachand, F.; Bahler, J.

10.1101/158477 — genomics — Posted on 2017-08-04

1264 A New Mechanism for Cost Savings in NHS Prescribing: Minimising "Price-Per-Unit"

Croker, R.; Walker, A. J.; Bacon, S.; Curtis, H.; French, L.; Goldacre, B.

10.1101/172569 — epidemiology — Posted on 2017-08-04

1265 Centenarian Hotspots in Denmark

Hansen, A. V.; Mortensen, L. H.; Westendorp, R.

10.1101/170654 — epidemiology — Posted on 2017-08-04

1266 Climate change drives uncertain global shifts in potential distribution and seasonal risk of Aedes-transmitted viruses

Ryan, S. J.; Carlson, C. J.; Mordecai, E. A.; Johnson, L. R.

10.1101/172221 — epidemiology — Posted on 2017-08-04

1267 The Impact of Education on Myopia: A bidirectional Mendelian randomisation analysis in UK Biobank

Mountjoy, E. J.; Davies, N. M.; Plotnikov, D.; Davey Smith, G.; Rodriguez, S.; Williams, C.; Guggenheim, J. A.; Atan, D.

10.1101/172247 — epidemiology — Posted on 2017-08-04

1268 Targeting Vaccinations for the Licensed Dengue Vaccine: Considerations for Serosurvey Design

Imai, N.; Ferguson, N.

10.1101/171140 — epidemiology — Posted on 2017-08-04

1269 Uncovering Medical Insights from Vast Amounts of Biomedical Data in Clinical Case Reports

Zhou, Y.; Liem, D. A.; Lee, J. M.; Cao, Q.; Bleakley, B.; Caufield, J. H.; Murali, S.; Wang, W.; Zhang, L.; Bui, A.; Sun, Y.; Watson, K. E.; Han, J.; Ping, P.

10.1101/172460 — bioinformatics — Posted on 2017-08-04

1270 An Efficient Moments-Based Inference Method for Within-Host Bacterial Infection Dynamics

Price, D.; Breuze, A.; Dybowski, R.; Mastroeni, P.; Restif, O.

10.1101/116319 — microbiology — Posted on 2017-08-04

1271 Empirical evidence reveals the phase diagram of vegetation patterns in Mediterranean drylands

Meloni, F.; Nakamura, G. M.; Granzotti, C. R. F.; Martinez, A. S.

10.1101/171835 — ecology — Posted on 2017-08-04

1272 Protection of the human gut microbiome from antibiotics

de Gunzburg, J.; Ghozlane, A.; Ducher, A.; Le Chatelier, E.; Duval, X.; Ruppe, E.; Armand-Lefevre, L.; Sablier-Gallis, F.; Burdet, C.; Alavoine, L.; Chachaty, E.; Augustin, V.; Varastet, M.; Levenez, F.; Kennedy, S.; Pons, N.; Mentre, F.; Andremont, A.

10.1101/169813 — clinical trials — Posted on 2017-08-04

1273 Systematic analysis of cell phenotypes and cellular social networks in tissues using the histology topography cytometry analysis toolbox (histoCAT)

Schapiro, D.; Jackson, H. W.; Raghuraman, S.; Zanotelli, V. R. T.; Fischer, J. R.; Schulz, D.; Giesen, C.; Catena, R.; Varga, Z.; Bodenmiller, B.

10.1101/109207 — systems biology — Posted on 2017-08-04

1274 Chromosome contacts in activated T cells identify autoimmune disease candidate genes

10.1101/100958 — genomics — Posted on 2017-08-04

1275 Genomes of an entire Plasmodium subgenus reveal paths to virulent human malaria

Otto, T. D.; Gilabert, A.; Crellen, T.; Böhme, U.; Arnathau, C.; Sanders, M.; Oyola, S.; Okauga, A. P.; Boundenga, L.; Wuillaume, E.; Ngoubangoye, B.; Moukodoum, N.; Paupy, C.; Durand, P.; Rougeron, V.; Ollomo, B.; Renaud, F.; Newbold, C.; Berriman, M.; Prugnolle, F.

10.1101/095679 — evolutionary biology — Posted on 2017-08-04

1276 Protein phosphatase V ensures timely cell cycle remodeling during the mid-blastula transition in Drosophila

Liu, B.; Sung, H.-w.; Gregor, I.; Müller, A.; Grosshans, J.

10.1101/172379 — developmental biology — Posted on 2017-08-04

1277 SeedVicious: analysis of microRNA target and near-target sites

Marco, A.

10.1101/124529 — bioinformatics — Posted on 2017-08-04

1278 Mineral analysis of complete dog and cat foods in the UK and compliance with European guidelines

Davies, M.; Jones, L.; Alborough, R.; Davis, C.; Williams, C.; Gardner, D. S.

10.1101/172544 — zoology — Posted on 2017-08-04

1279 Piper longum Linn: A review of its phytochemicals and their network pharmacological evaluation

Choudhary, N.; Singh, V.

10.1101/169763 — systems biology — Posted on 2017-08-04

1280 Cell-free prediction of protein expression costs for growing cells

Borkowski, O.; Bricio Garberi, C.; Murgiano, M.; Stan, G.-B.; Ellis, T.

10.1101/172627 — synthetic biology — Posted on 2017-08-04

1281 Catecholamines, not acetylcholine, alter cortical and perceptual dynamics in line with increased excitation inhibition ratio

Pfeffer, T.; Avramiea, A.-E.; Nolte, G.; Engel, A. K.; Linkenkaer-Hansen, K.; Donner, T. H.

10.1101/170613 — neuroscience — Posted on 2017-08-04

1282 Domain-Specific Patterns of Activity Support Metacognition in Human Prefrontal Cortex

Morales, J.; Lau, H.; Fleming, S. M.

10.1101/172445 — neuroscience — Posted on 2017-08-04

1283 Multi-clonal evolution of MDR/XDR M. tuberculosis in a high prevalence setting in Papua New Guinea over three decades

Bainomugisa, A.; Lavu, E.; Hiashiri, S.; Majumdar, S.; Honjepari, A.; Moke, R.; Dakulala, P.; Hill-Cawthorne, G. A.; Pandey, S.; Marais, B. J.; Coulter, C.; Coin, L. J. M.

10.1101/172601 — microbiology — Posted on 2017-08-04

1284 Genomic investigation of an outbreak of carbapenemase-producing Enterobacter cloacae: long-read sequencing reveals the context of blaIMP4 on a widely distributed IncHI2 plasmid

Roberts, L. W.; Harris, P. N. A.; Ben Zakour, N. L.; Forde, B. M.; Catchpoole, E.; Stanton-Cook, M.; Phan, M.-D.; Sidjabat, H.; Bergh, H.; Heney, C.; Gawthorne, J. A.; Lipman, J.; Allworth, A.; Chan, K.-G.; Chong, T. M.; Yin, W.-F.; Schembri, M. A.; Paterson, D. L.; Beatson, S.

10.1101/172536 — genomics — Posted on 2017-08-04

1285 ShhN-mediated activation of Smo in the absence of Ptch1/2 function

Casillas, C.; Roelink, H.

10.1101/172429 — developmental biology — Posted on 2017-08-04

1286 Clearance of senescent decidual cells by uterine natural killer cells drives endometrial remodeling during the window of implantation

Brighton, P. J.; Maruyama, Y.; Fishwick, K.; Vrljicak, P.; Tewary, S.; Fujihara, R.; Muter, J.; Lucas, E. S.; Yamada, T.; Woods, L.; Lucciola, R.; Lee, Y. H.; Takeda, S.; Ott, S.; Hemberger, M.; Quenby, S.; Brosens, J. J.

10.1101/172593 — cell biology — Posted on 2017-08-04

1287 Regulation of mesenchymal stem cell function by TGFβ-1 on mast cell extracellular vesicles -- role of endosomal retention

Yin, Y.; Shelke, G. V.; Jang, S. C.; Lasser, C.; Wennmalm, S.; Hoffmann, H. J.; Nilsson, J.; Li, L.; Gho, Y. S.; Lotvall, J.

10.1101/172213 — cell biology — Posted on 2017-08-04

1288 SVclone: inferring structural variant cancer cell fraction

Cmero, M.; Ong, C. S.; Yuan, K.; Schröder, J.; Mo, K.; PCAWG Evolution and Heterogeneity Working Group, ; Corcoran, N. M.; Papenfuss, A. T.; Hovens, C. M.; Markowetz, F.; Macintyre, G.

10.1101/172486 — cancer biology — Posted on 2017-08-04

1289 Liver physiological T1rho dynamics associated with age and gender

Wang, Y.-X.; Deng, M.; Li, J.; Kwok, A.; Liu, E.; Chen, W.

10.1101/172478 — biophysics — Posted on 2017-08-04

1290 SEA: The Small RNA Expression Atlas

Rahman, R.-U.; Sattar, A.; Fiosins, M.; Gautam, A.; Magruder, D. S.; Bethune, J.; Madan, S.; Fluck, J.; Bonn, S.

10.1101/133199 — bioinformatics — Posted on 2017-08-04

1291 Uncovering Medical Insights from Vast Amounts of Biomedical Data in Clinical Case Reports

Zhou, Y.; Liem, D. A.; Lee, J. M.; Cao, Q.; Bleakley, B.; Caufield, J. H.; Murali, S.; Wang, W.; Zhang, L.; Bui, A.; Sun, Y.; Watson, K. E.; Han, J.; Ping, P.

10.1101/172460 — bioinformatics — Posted on 2017-08-04

1292 Substrate binding and specificity appear as major forces in the functional diversification of eqolisins.

Revuelta, M. V.; Stocchi, N.; Lanza Castronuovo, P. A.; Vera, M.; ten Have, A.

10.1101/167544 — bioinformatics — Posted on 2017-08-04

1293 Reverse Association Of Single Cells To Rheumatoid Arthritis Accounting For Mixed Effects Identifies An Expanded CD27- HLA-DR+ Effector Memory CD4+ T Cell Population

Fonseka, C. Y.; Rao, D. A.; Teslovich, N. C.; Hannes, S. K.; Slowikowski, K.; Gurish, M. F.; Donlin, L. T.; Weinblatt, M. E.; Massarotti, E. M.; Coblyn, J. S.; Helfgott, S. M.; Todd, D. J.; Bykerk, V. P.; Karlson, E. W.; Ermann, J.; Lee, Y. C.; Brenner, M. B.; Raychaudhuri, S.

10.1101/172403 — bioinformatics — Posted on 2017-08-04

1294 Harnessing sleep/wake state tracking by olfactory bulb oscillations to perform fully brain-based sleep scoring in mice

Bagur, S.; Lacroix, M. M.; de Lavilleon, G.; Lefort, J. M.; Geoffroy, H.; Benchenane, K.

10.1101/109033 — neuroscience — Posted on 2017-08-04

1295 Task Demands Predict a Dynamic Switch in the Content of Awake Hippocampal Replay

Olafsdottir, H. F.; Carpenter, F.; Barry, C.

10.1101/172098 — neuroscience — Posted on 2017-08-04

1296 Chromatin domains are encoded and molded by isochores

Bernardi, G.

10.1101/096487 — genomics — Posted on 2017-08-04

1297 Enabling cross-study analysis of RNA-Sequencing data

Wang, Q.; Armenia, J.; Zhang, C.; Penson, A. V.; Reznik, E.; Zhang, L.; Minet, T.; Ochoa, A.; Gross, B. E.; Iacobuzio-Donahue, C. A.; Betel, D.; Taylor, B. S.; Gao, J.; Schultz, N.

10.1101/110734 — bioinformatics — Posted on 2017-08-04

1298 Beyond Brownian motion and the Ornstein-Uhlenbeck process: Stochastic diffusion models for the evolution of quantitative characters.

Blomberg, S. P.

10.1101/067363 — evolutionary biology — Posted on 2017-08-04

1299 How Fast Fast-Folding Proteins Fold in Silico

Pang, Y.-P.

10.1101/088849 — biophysics — Posted on 2017-08-04

1300 Dynamics of brain activity reveal a unitary recognition signal

Weidemann, C. T.; Kahana, M. J.

10.1101/165225 — neuroscience — Posted on 2017-08-03

1301 Euplotid: A Linux-based platform to physically edit the genome

Borges, D.

10.1101/170159 — biophysics — Posted on 2017-08-03

1302 Detailed Analyses Of Stall Force Generation In Mycoplasma mobile Gliding

Mizutani, M.; Tulum, I.; Kinosita, Y.; Nishizaka, T.; Miyata, M.

10.1101/142133 — biophysics — Posted on 2017-08-03

1303 Ingredients in Victoria’s Secret Bombshell and Ivanka Trump eaux de parfums that repel mosquitoes

Zeng, F.; Xu, P.; Tan, K.; Zarbin, P.; Leal, W.

10.1101/172304 — physiology — Posted on 2017-08-03

1304 Ageing synaptic vesicles are inactivated by contamination with SNAP25

Truckenbrodt, S.; Viplav, A.; Jaehne, S.; Vogts, A.; Denker, A.; Wildhagen, H.; Fornasiero, E. F.; Rizzoli, S. O.

10.1101/172239 — neuroscience — Posted on 2017-08-03

1305 Dissociable components of the reward circuit are involved in appraisal versus choice

Shenhav, A.; Karmarkar, U. R.

10.1101/172320 — neuroscience — Posted on 2017-08-03

1306 Confidence-dependent accumulation of past decision variables biases perceptual choice

Braun, A.; Urai, A. E.; Donner, T. H.

10.1101/172049 — neuroscience — Posted on 2017-08-03

1307 Linear relationship between peak and season-long abundances in insects

Onufrieva, K. S.; Onufriev, A. V.

10.1101/172270 — ecology — Posted on 2017-08-03

1308 A quantitative chemotherapy genetic interaction map reveals new factors associated with PARP inhibitor resistance

Hu, H.-M.; Zhao, X.; Kaushik, S.; Robillard, L.; Barthelet, A.; Lin, K. K.; Simmons, A.; Raponi, M.; Harding, T. C.; Bandyopadhyay, S.

10.1101/171918 — cancer biology — Posted on 2017-08-03

1309 Bots for Software-Assisted Analysis of Image-Based Transcriptomics

Cicconet, M.; Hochbaum, D. R.; Richmond, D.; Sabatini, B. L.

10.1101/172296 — bioinformatics — Posted on 2017-08-03

1310 Tolloid cleavage activates latent GDF8 by priming the pro-complex for dissociation

Le, V. Q.; Iacob, R. E.; Tian, Y.; McConaughy, W.; Jackson, J.; Su, Y.; Zhao, B.; Engen, J. R.; Pirruccello-Straub, M.; Springer, T. A.

10.1101/154823 — biochemistry — Posted on 2017-08-03

1311 The GSS is an unreliable indicator of biological sciences postdoc population trends

Pickett, C.; Bankston, A.; McDowell, G. S.

10.1101/171314 — scientific communication and education — Posted on 2017-08-03

1312 Heterogeneity and Intrinsic Variation in Spatial Genome Organization

Finn, E.; Pegoraro, G.; Brandao, H. B.; Valton, A.-L.; Oomen, M. E.; Dekker, J.; Mirny, L.; Misteli, T.

10.1101/171801 — molecular biology — Posted on 2017-08-03

1313 Oasis2.0: improved online analysis of small RNA-seq data

Rahman, R.-U.; Gautam, A.; Bethune, J.; Sattar, A.; Fiosins, M.; Magruder, D. S.; Capece, V.; Shomroni, O.; Bonn, S.

10.1101/170738 — bioinformatics — Posted on 2017-08-03

1314 Hebbian Learning in a Random Network Captures Selectivity Properties of Prefrontal Cortex

Lindsay, G. W.; Rigotti, M.; Warden, M. R.; Miller, E. K.; Fusi, S.

10.1101/133025 — neuroscience — Posted on 2017-08-03

1315 Systematic mapping of chromatin state landscapes during mouse development

Gorkin, D.; Barozzi, I.; Zhang, Y.; Lee, A. Y.; Lee, B.; Zhao, Y.; Wildberg, A.; Ding, B.; Zhang, B.; Wang, M.; Strattan, J. S.; Davidson, J. M.; Qiu, Y.; Afzal, V.; Akiyama, J. A.; Plajzer-Frick, I.; Pickle, C. S.; Kato, M.; Garvin, T. H.; Pham, Q. T.; Harrington, A. N.; Mannion, B. J.; Lee, E. A.; Fukuda-Yuzawa, Y.; He, Y.; Preissl, S.; Chee, S.; Williams, B. A.; Trout, D.; Amrhein, H.; Yang, H.; Cherry, J. M.; Shen, Y.; Ecker, J. R.; Wang, W.; Dickel, D. E.; Visel, A.; Pennacchio, L. A.; Ren, B.

10.1101/166652 — genomics — Posted on 2017-08-03

1316 Innovative assembly strategy contributes to the understanding of evolution and conservation genetics of the critically endangered Solenodon paradoxus from the island of Hispaniola

Grigorev, K.; Kliver, S.; Dobrynin, P.; Komissarov, A.; Wolfsberger, W.; Krasheninnikova, K.; Afanador-Hernandez, Y. M.; Paulino, L. A.; Carreras, R.; Rodriguez, L. E.; Nunez, A.; Silva, F.; Hernandez-Martich, D.; Majeske, A. J.; Antunes, A.; Roca, A. L.; O'Brien, S. J.; Martinez-Cruzado, J. C.; Oleksyk, T. K.

10.1101/164574 — evolutionary biology — Posted on 2017-08-03

1317 Compartmental and spatial rule-based modeling with Virtual Cell (VCell)

Blinov, M. L.; Schaff, J. C.; Vasilescu, D.; Moraru, I. I.; Bloom, J. E.; Loew, L. M.

10.1101/146225 — biophysics — Posted on 2017-08-03

1318 Wilms Tumor 1b defines a wound-specific sheath cell subpopulation associated with notochord repair

Lopez-Baez, J. C.; Zeng, Z.; Rybski, W.; Huitema, L. F. A.; Brombin, A.; Dale, R. M.; Kawakami, K.; Englert, C.; Schulte-Merker, S.; Hastie, N. D.; Patton, E. E.

10.1101/172288 — developmental biology — Posted on 2017-08-03

1319 Applying expression profile similarity for discovery of patient-specific functional mutations

Meng, G.

10.1101/172015 — bioinformatics — Posted on 2017-08-03

1320 Collection and Storage of HLA NGS Genotyping Data for the 17th International HLA and Immunogenetics Workshop

Chang, C.-J.; Osoegawa, K.; Milius, R. P.; Maiers, M.; Xiao, W.; Fernandez-Vina, M. A.; Mack, S. J.

10.1101/116871 — bioinformatics — Posted on 2017-08-03

1321 Kinesin-6 KIF20B is required for efficient cytokinetic furrowing and timely abscission in human cells

Janisch, K. M.; McNeely, K. C.; Dardick, J. M.; Lim, S. H.; Dwyer, N. D.

10.1101/171900 — cell biology — Posted on 2017-08-03

1322 Spot-On: robust model-based analysis of single-particle tracking experiments

Hansen, A. S.; Woringer, M.; Grimm, J. B.; Lavis, L. D.; Tjian, R.; Darzacq, X.

10.1101/171983 — biophysics — Posted on 2017-08-03

1323 Pathway centrality in protein interaction networks identifies functional mediators of pulmonary disease

Park, J.; Hescott, B. J.; Slonim, D. K.

10.1101/171942 — bioinformatics — Posted on 2017-08-03

1324 T1 white/gray contrast as a predictor of chronological age, and an index of cognitive performance

Lewis, J. D.; Evans, A. C.; Tohka, J.

10.1101/171892 — neuroscience — Posted on 2017-08-03

1325 Midfrontal theta and pupil dilation parametrically track subjective conflict (but also surprise) during intertemporal choice

Lin, H.; Saunders, B.; Hutcherson, C. A.; Inzlicht, M.

10.1101/172122 — neuroscience — Posted on 2017-08-03

1326 New waves: Rhythmic electrical field stimulation systematically alters spontaneous slow dynamics across mouse neocortex

Greenberg, A.; Karimi Abadchi, J.; Dickson, C. T.; Mohajerani, M.

10.1101/171926 — neuroscience — Posted on 2017-08-03

1327 Programming of neural progenitors of the adult subependymal zone towards a glutamatergic identity by neurogenin2

Peron, S.; Miyakoshi, L. M.; Brill, M. S.; Ortega, F.; Karow, M.; Gascon, S.; Berninger, B.

10.1101/171686 — neuroscience — Posted on 2017-08-03

1328 Seizure epicenter depth and translaminar field potential synchrony underlie complex variations in tissue oxygenation during ictal initiation.

Harris, S. S.; Boorman, L. W.; Kennerley, A. J.; Sharp, P. S.; Martin, C.; Redgrave, P.; Schwartz, T. H.; Berwick, J.

10.1101/172148 — neuroscience — Posted on 2017-08-03

1329 Role of KCC2-Dependent Potassium Efflux in 4-Aminopyridine-Induced Epileptiform Synchronization

Gonzalez, O. C.; Shiri, Z.; Krishnan, G. P.; Myers, T. L.; Williams, S.; Avoli, M.; Bazhenov, M.

10.1101/171488 — neuroscience — Posted on 2017-08-03

1330 Convex Optimized Population Receptive Field (CO-pRF) Mapping

Slater, D.; Melie-Garcia, L.; Adaszewski, S.; Kay, K.; Lutti, A.; Draganski, B.; Kherif, F.

10.1101/172189 — neuroscience — Posted on 2017-08-03

1331 Heritable cognitive and psychopathology factors in youth are predicted by brain fronto-temporal white matter pathway

Alnaes, D.; Kaufmann, T.; Doan, N. T.; Cordova-Palomera, A.; Wang, Y.; Bettella, F.; Moberget, T.; Andreassen, O. A.; Westlye, L. T.

10.1101/172080 — neuroscience — Posted on 2017-08-03

1332 First Draft Genome Sequence of the Pathogenic Fungus Lomentospora prolificans (formerly Scedosporium prolificans)

Luo, R.; Zimin, A.; Workman, R.; Fan, Y.; Pertea, G.; Grossman, N.; Wear, M.; Jia, B.; Miller, H.; Casadevall, A.; Timp, W.; Zhang, S.; Salzberg, S.

10.1101/171975 — microbiology — Posted on 2017-08-03

1333 Anti-infective potential of a quorum modulatory polyherbal extract (Panchvalkal) against certain pathogenic bacteria

Patel, P.; Joshi, C.; Palep, H.; Kothari, V.

10.1101/172056 — microbiology — Posted on 2017-08-03

1334 A Model for Genome-First Care: Returning Secondary Genomic Findings to Participants and Their Healthcare Providers in a Large Research Cohort

Schwartz, M. L. B.; McCormick, C. Z.; Lazzeri, A. L.; Lindbuchler, D. M.; Hallquist, M. L. G.; Manickam, K.; Buchanan, A. H.; Rahm, A. K.; Giovanni, M. A.; Frisbie, L.; Flansburg, C. N.; Davis, F. D.; Sturm, A. C.; Nicastro, C.; Lebo, M. S.; Mason-Suares, H.; Mahanta, L. M.; Carey, D. J.; Williams, J. L.; Williams, M. S.; Ledbetter, D. H.; Faucett, W. A.; Murray, M. F.

10.1101/166975 — genomics — Posted on 2017-08-03

1335 Optimization of selective phenotyping and population design for genomic prediction

Heslot, N.; Feoktistov, V.

10.1101/172064 — genetics — Posted on 2017-08-03

1336 Individual heterogeneity and capture-recapture models: what, why and how?

Gimenez, O.; Cam, E.; Gaillard, J.-M.

10.1101/120683 — ecology — Posted on 2017-08-03

1337 Empirical evidence reveals the phase diagram of vegetation patterns in Mediterranean drylands

Meloni, F.; Nakamura, G. M.; Granzotti, C. R. F.; Martinez, A. S.

10.1101/171835 — ecology — Posted on 2017-08-03

1338 The structured demography of open populations in fluctuating environments

Schreiber, S.; Moore, J.

10.1101/171884 — ecology — Posted on 2017-08-03

1339 Fog and live fuel moisture in coastal California shrublands

Emery, N.; D'Antonio, C. M.; Still, C. J.

10.1101/171850 — ecology — Posted on 2017-08-03

1340 Effect of 40Gy irradiation on the ultrastructure, biochemistry, morphology and cytology during spermatogenesis in the southern green stink bug Nezara viridula (Hemiptera: Pentatomidae)

Stringer, L.; Harland, D.; Grant, J. E.; Laban, J.; Suckling, D.

10.1101/171991 — developmental biology — Posted on 2017-08-03

1341 The contributions of the actin machinery to endocytic membrane bending and vesicle formation

Picco, A.; Kukulski, W.; Manenschijn, H. E.; Specht, T.; Briggs, J. A. G.; Kaksonen, M.

10.1101/172072 — cell biology — Posted on 2017-08-03

1342 Symmetric, explicit numerical integrator for molecular dynamics equations of motion with a generalized friction

Fukuda, I.

10.1101/172023 — biophysics — Posted on 2017-08-03

1343 Biophysical determinants of mutational robustness in a viral molecular fitness landscape

Pethe, M. A.; Rubenstein, A. B.; Zorine, D.; Khare, S. D.

10.1101/172197 — biophysics — Posted on 2017-08-03

1344 System-level studies of a cell-free transcription-translation platform for metabolic engineering

Wu, Y. Y.; Sato, H.; Huang, H.; Culler, S. J.; Khandurina, J.; Nagarajan, H.; Yang, T. H.; Van Dien, S.; Murray, R. M.

10.1101/172007 — bioengineering — Posted on 2017-08-03

1345 An improved method for the expression screening of membrane protein-GFP fusions in yeast

Baldock, D.; Sheldon, J.; Tailor, R.; Green, K.; Ray, J.; Singh, S.; Brocklehurst, K.

10.1101/172114 — biochemistry — Posted on 2017-08-03

1346 Revisiting Chemoaffinity Theory: Chemotactic Implementation Of Topographic Axonal Projection

Naoki, H.

10.1101/136291 — neuroscience — Posted on 2017-08-03

1347 FlyClockbase: Importance of Biological Model Curation for Analyzing Variability in the Circadian Clock of Drosophila melanogaster by Integrating Time Series from 25 Years of Research

Scheuer, K. S.; Hanlon, B.; Dresel, J. W.; Nolan, E. D.; Davis, J. C.; Loewe, L.

10.1101/099192 — genetics — Posted on 2017-08-03

1348 Non-random mating and information theory

Carvajal-Rodriguez, A.

10.1101/095901 — evolutionary biology — Posted on 2017-08-03

1349 A cascade of destabilizations: combining Wolbachia and Allee effects to eradicate insect pests

Blackwood, J. C.; Vargas, R.; Fauvergue, X.

10.1101/064774 — ecology — Posted on 2017-08-03

1350 Single-cell RNA-Sequencing uncovers transcriptional states and fate decisions in haematopoiesis

Athanasiadis, E. I.; Botthof, J.; Andres, H.; Ferreira, L.; Lio, P.; Cvejic, A.

10.1101/117960 — cell biology — Posted on 2017-08-03

1351 A dynamic microbial community with high functional redundancy inhabits the cold, oxic subseafloor aquifer

Tully, B.; Wheat, C. G.; Glazer, B. T.; Huber, J.

10.1101/171934 — microbiology — Posted on 2017-08-03

1352 Intra- and inter-chromosomal chromatin interactions mediate genetic effects on regulatory networks

Delaneau, O.; Zazhytska, M.; Borel, C.; Howald, C.; Kumar, S.; Ongen, H.; Popadin, K.; Marbach, D.; Ambrosini, G.; Bielser, D.; Hacker, D.; Romano-Palumbo, L.; Ribaux, P.; Wiederkehr, M.; Falconnet, E.; Bucher, P.; Bergmann, S.; Antonarakis, S.; Reymond, A.; Dermitzakis, E.

10.1101/171694 — genomics — Posted on 2017-08-03

1353 Bioinformatics Core Competencies for Undergraduate Life Sciences Education

Wilson Sayres, M. A.; Hauser, C.; Sierk, M.; Robic, S.; Rosenwald, A. G.; Smith, T. M.; Triplett, E. W.; Williams, J. J.; Dinsdale, E.; Morgan, W.; Burnette, J. M.; Donovan, S. S.; Drew, J. C.; Elgin, S. C. R.; Fowlks, E. R.; Galindo-Gonzalez, S.; Goodman, A. L.; Grandgenett, N. F.; Goller, C. C.; Jungck, J.; Newman, J. D.; Pearson, W. R.; Ryder, E.; Tosado-Acevedo, R.; Tapprich, W.; Tobin, T. C.; Toro-Martinez, A.; Welch, L. R.; Wright, R.; Ebenbach, D.; Olney, K. C.; McWilliams, M.; Pauley, M. A.

10.1101/170993 — bioinformatics — Posted on 2017-08-03

1354 Heterologous expression of the immune receptor EFR in Medicago truncatula reduces pathogenic infection, but not rhizobial symbiosis

Pfeilmeier, S.; George, J.; Morel, A.; Roy, S.; Smoker, M.; Stansfeld, L.; Downie, A.; Peeters, N.; Malone, J.; Zipfel, C.

10.1101/171868 — plant biology — Posted on 2017-08-02

1355 C-BERST: Defining subnuclear proteomic landscapes at genomic elements with dCas9-APEX2

Gao, X. D.; Tu, L.-C.; Mir, A.; Dekker, J.; Shaffer, S. A.; Zhu, L. J.; Wolfe, S. A.; Sontheimer, E. J.

10.1101/171819 — molecular biology — Posted on 2017-08-02

1356 Characterization of a thalamic nucleus mediating habenula responses to change in illumination

Cheng, R. K.; Krishnan, S.; Lin, Q.; Kibat, C.; Jesuthasan, S.

10.1101/047936 — neuroscience — Posted on 2017-08-02

1357 Chromosome arm specific patterns of polymorphism associated with chromosomal inversions in the major African malaria vector, Anopheles funestus

Kamdem, C.; Fouet, C.; White, B. J.

10.1101/068205 — evolutionary biology — Posted on 2017-08-02

1358 Lessons in effector and NLR biology of plant-microbe systems

Bialas, A.; Zess, E. K.; De la Concepcion, J. C.; Franceschetti, M.; Pennington, H. G.; Yoshida, K.; Upson, J. L.; Chanclud, E.; Wu, C.-H.; Langner, T.; Maqbool, A.; Varden, F. A.; Derevnina, L.; Belhaj, K.; Fujisaki, K.; Saitoh, H.; Terauchi, R.; Banfield, M. J.; Kamoun, S.

10.1101/171223 — plant biology — Posted on 2017-08-02

1359 Cognitive task information is transferred between brain regions via resting-state network topology

Ito, T.; Kulkarni, K. R.; Schultz, D. H.; Mill, R. D.; Chen, R. H.; Solomyak, L. I.; Cole, M. W.

10.1101/101782 — neuroscience — Posted on 2017-08-02

1360 Gravitational and dynamic components of muscle torque underlie tonic and phasic muscle activity during goal-directed reaching.

Olesh, E.; Pollard, B.; Gritsenko, V.

10.1101/138263 — neuroscience — Posted on 2017-08-02

1361 Distinct Laminar Processing of Local and Global Context in Primate Primary Visual Cortex

Bijanzadeh, M.; Nurminen, L.; Merlin, S.; Angelucci, A.

10.1101/171793 — neuroscience — Posted on 2017-08-02

1362 Optogenetic silencing of primary afferents reduces evoked and ongoing bladder pain

Samineni, V. K.; Mickle, A. D.; Yoon, J.; Grajales-Reyes, J. G.; Pullen, M.; Crawford, K.; Noh, K. N.; Gereau, G.; Vogt, S.; Lai, H.; Rogers, J.; Gereau, R.

10.1101/167841 — neuroscience — Posted on 2017-08-02

1363 Neural Networks for Efficient Bayesian Decoding of Natural Images from Retinal Neurons

Parthasarathy, N.; Batty, E.; Falcon, W.; Rutten, T.; Rajpal, M.; Chichilnisky, E. J.; Paninski, L.

10.1101/153759 — neuroscience — Posted on 2017-08-02

1364 Heterogeneity and Intrinsic Variation in Spatial Genome Organization

Finn, E.; Pegoraro, G.; Brandao, H. B.; Valton, A.-L.; Oomen, M. E.; Dekker, J.; Mirny, L.; Misteli, T.

10.1101/171801 — molecular biology — Posted on 2017-08-02

1365 Functional histamine H3 and adenosine A2A receptor heteromers in recombinant cells and rat striatum

Marquez-Gomez, R.; Gutierrez-Rodelo, C.; Robins, M. T.; Arias, J.-M.; Olivares-Reyes, J.-A.; van Rijn, R. M.; Arias-Montano, J.-A.

10.1101/171736 — neuroscience — Posted on 2017-08-02

1366 Decomposing the neural pathways mediating value-based choice

Koscik, T. R.; Man, V.; Jahn, A.; Lee, C. H.; Cunningham, W. A.

10.1101/171744 — neuroscience — Posted on 2017-08-02

1367 Adiposity QTL Adip20 decomposes into at least four loci when dissected using congenic strains

Lin, C.; Fesi, B. D.; Marquis, M.; Bosak, N. P.; Lysenko, A.; Koshnevisan, M. A.; Duke, F. F.; Theodorides, M. L.; Nelson, T. M.; McDaniel, A. H.; Avigdor, M.; Arayata, C. J.; Shaw, L.; Bachmanov, A. A.; Reed, D. R.

10.1101/171777 — genetics — Posted on 2017-08-02

1368 Differences in the genetic control of early egg development and reproduction between C. elegans and its parthenogenetic relative D. coronatus

Kraus, C.; Schiffer, P. H.; Kagoshima, H.; Hiraki, H.; Vogt, T.; Kroiher, M.; Kohara, Y.; Schierenberg, E.

10.1101/171769 — evolutionary biology — Posted on 2017-08-02

1369 Evaluating anthropogenic noise impacts on animals in natural areas

Keyel, A. C.; Reed, S. E.; Nuessly, K.; Cinto-Meija, E.; Barber, J. R.; Wittemyer, G.

10.1101/171728 — ecology — Posted on 2017-08-02

1370 The impact of experimental design choices on parameter inference for models of growing cell colonies

Parker, A.; Simpson, M. J.; Baker, R. E.

10.1101/171710 — cell biology — Posted on 2017-08-02

1371 The harmonic mean p-value and model averaging by mean maximum likelihood

Wilson, D. J.

10.1101/171751 — bioinformatics — Posted on 2017-08-02

1372 Fitness effects of cis-regulatory variants in the Saccharomyces cerevisiae TDH3 promoter

Duveau, F.; Toubiana, W.; Wittkopp, P. J.

10.1101/154039 — genetics — Posted on 2017-08-02

1373 GWAS results for educational attainment aid in identifying genetic heterogeneity of schizophrenia

Bansal, V.; Mitjans, M.; Burik, C. A. P.; Karlsson Linner, R.; Okbay, A.; Rietveld, C. A.; Begemann, M.; Bonn, S.; Ripke, S.; Vlaming, R. d.; Nivard, M. G.; Ehrenreich, H.; Koellinger, P. D.

10.1101/114405 — genetics — Posted on 2017-08-02

1374 Polygenic Adaptation has Impacted Multiple Anthropometric Traits

Berg, J. J.; Zhang, X.; Coop, G.

10.1101/167551 — evolutionary biology — Posted on 2017-08-02

1375 Euplotid: A Linux-based platform to physically edit the genome

Borges, D.; Young, R.

10.1101/170159 — biophysics — Posted on 2017-08-02

1376 Shaping dendritic NMDA spikes by timed synaptic inhibition: Implications for the I/O properties of cortical neurons

Doron, M.; Chindemi, G.; Muller, E.; Markram, H.; Segev, I.

10.1101/171629 — neuroscience — Posted on 2017-08-02

1377 Roles of the Brca2 and Wapl complexes with Pds5 in sister chromatid cohesion, cohesin localization, and gene expression

Misulovin, Z.; Pherson, M.; Gause, M.; Mihindukulasuriya, K.; Dorsett, D.

10.1101/170829 — molecular biology — Posted on 2017-08-02

1378 Metabolic roles of uncultivated bacterioplankton lineages in the northern Gulf of Mexico "Dead Zone"

Thrash, J. C.; Seitz, K. W.; Baker, B. J.; Temperton, B.; Gillies, L. E.; Rabalais, N. N.; Henrissat, B.; Mason, O. U.

10.1101/095471 — microbiology — Posted on 2017-08-02

1379 The Reproducibility Of Research And The Misinterpretation Of P Values

Colquhoun, D.

10.1101/144337 — scientific communication and education — Posted on 2017-08-02

1380 Cftr Modulates Wnt/β-Catenin Signaling and Stem Cell Proliferation in Murine Intestine

Strubberg, A. M.; Liu, J.; Walker, N. M.; Stefanski, C. D.; MacLeod, R. J.; Magness, S. T.; Clarke, L. L.

10.1101/156562 — physiology — Posted on 2017-08-02

1381 Rehabilitation promotes the recovery of distinct functional and structural features of healthy neuronal networks after stoke

Allegra Mascaro, A. L.; Conti, E.; Lai, S.; Di Giovanna, A. P.; Spalletti, C.; Alia, C.; Quarta, E.; Panarese, A.; Sacconi, L.; Micera, S.; Caleo, M.; Pavone, F. S.

10.1101/141697 — neuroscience — Posted on 2017-08-02

1382 Effects of the glucocorticoid drug prednisone on urinary proteome and candidate biomarkers

Wu, J.; Li, X.; An, M.; Gao, Y.

10.1101/128603 — molecular biology — Posted on 2017-08-02

1383 ISG15 induces IL-10 production in human monocytes and is a biomarker of disease severity during active tuberculosis

dos Santos, P. F.; Van Weyenbergh, J.; Delgobo, M.; Patricio, D. d. O.; Ferguson, B. J.; GUABIRABA, R.; Dierckx, T.; MENEZES, S. M. M.; Bafica, A.; Mansur, D. S.

10.1101/166553 — immunology — Posted on 2017-08-02

1384 TreeTime: maximum likelihood phylodynamic analysis

Sagulenko, P.; Puller, V.; Neher, R.

10.1101/153494 — evolutionary biology — Posted on 2017-08-02

1385 Aggressiveness as a latent personality trait of domestic dogs: testing local independence and measurement invariance

Goold, C.; Newberry, R. C.

10.1101/117440 — animal behavior and cognition — Posted on 2017-08-02

1386 Modelling personality, plasticity and predictability in shelter dogs

Goold, C.; Newberry, R. C.

10.1101/145367 — animal behavior and cognition — Posted on 2017-08-02

1387 Mechanistic hierarchical population model identifies latent causes of cell-to-cell variability

Loos, C.; Moeller, K.; Fröhlich, F.; Hucho, T.; Hasenauer, J.

10.1101/171561 — systems biology — Posted on 2017-08-02

1388 A microfluidic biodisplay

Volpetti, F.; Petrova, E.; Maerkl, S. J.

10.1101/112110 — synthetic biology — Posted on 2017-08-02

1389 The GSS is an unreliable indicator of biological sciences postdoc population trends

Pickett, C.; Bankston, A.; McDowell, G. S.

10.1101/171314 — scientific communication and education — Posted on 2017-08-02

1390 Dopaminergic drug effects on probability weighting during risky decision-making

Ojala, K. E.; Janssen, L. K.; Hashemi, M. M.; Timmer, M. H. M.; Geurts, D. E. M.; ter Huurne, N. P.; Cools, R.; Sescousse, G.

10.1101/171587 — neuroscience — Posted on 2017-08-02

1391 Serial representation of items during working memory maintenance at letter-selective cortical sites

Bahramisharif, A.; Jensen, O.; Jacobs, J.; Lisman, J.

10.1101/171660 — neuroscience — Posted on 2017-08-02

1392 Dissociable neural mechanisms track evidence accumulation for selection of attention versus action

Shenhav, A.; Straccia, M. A.; Cohen, J. D.; Botvinick, M. M.

10.1101/171454 — neuroscience — Posted on 2017-08-02

1393 Spatial vision by macaque midbrain

Chen, C.-Y.; Sonnenberg, L.; Weller, S.; Witschel, T.; Hafed, Z. M.

10.1101/171645 — neuroscience — Posted on 2017-08-02

1394 Predicting motivation: computational models of PFC can explain neural coding of motivation and effort-based decision-making in health and disease

Vassena, E.; Deraeve, J.; Alexander, W.

10.1101/171637 — neuroscience — Posted on 2017-08-02

1395 Shaping dendritic NMDA spikes by timed synaptic inhibition: Implications for the I/O properties of cortical neurons

Doron, M.; Chindemi, G.; Muller, E.; Markram, H.; Segev, I.

10.1101/171629 — neuroscience — Posted on 2017-08-02

1396 An orphan cbb3-type cytochrome oxidase subunit supports Pseudomonas aeruginosa biofilm growth and virulence

Jo, J.; Cortez, K. L.; Cornell, W.-C.; Price-Whelan, A.; Dietrich, L. E. P.

10.1101/171538 — microbiology — Posted on 2017-08-02

1397 Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies

Manandhar, D.; Song, L.; Kabadi, A.; Kwon, J.; Edsall, L.; Ehrlich, M.; Tsumagari, K.; Gersbach, C.; Crawford, G.; Gordan, R.

10.1101/171470 — genomics — Posted on 2017-08-02

1398 Accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments

Petukhov, V.; Guo, J.; Baryawno, N.; Severe, N.; Scadden, D.; Kharchenko, P. V.

10.1101/171496 — genomics — Posted on 2017-08-02

1399 AMELIE accelerates Mendelian patient diagnosis directly from the primary literature

Birgmeier, J.; Haeussler, M.; Deisseroth, C. A.; Jagadeesh, K. A.; Ratner, A. J.; Guturu, H.; Wenger, A. M.; Stenson, P. D.; Cooper, D. N.; Re, C.; Bernstein, J. A.; Bejerano, G.

10.1101/171322 — genetics — Posted on 2017-08-02

1400 Restricted access to beneficial mutations slows adaptation and biases fixed mutations in diploids

Marad, D. A.; Lang, G. I.

10.1101/171462 — evolutionary biology — Posted on 2017-08-02

Bogdziewicz, M.; Steele, M. A.; Marino, S.; Crone, E. E.

10.1101/171579 — ecology — Posted on 2017-08-02

1402 Weak interactions between groups and physical drivers of community dynamics in coastal phytoplankton

Barraquand, F.; Picoche, C.; Maurer, D.; Carassou, L.; Auby, I.

10.1101/171264 — ecology — Posted on 2017-08-02

1403 Embryonic lethality in mice lacking Trim59 due to impaired gastrulation development

Su, X.; Wu, C.; Ye, X.; Zeng, M.; Zhang, Z.; Che, Y.; Zhang, Y.; Liu, L.; Lin, Y.; Yang, R.

10.1101/171603 — developmental biology — Posted on 2017-08-02

1404 Single-molecule assay for proteolytic susceptibility using centrifuge force microscopy: force-induced destabilization of collagen's triple helix

Kirkness, M. W. H.; Forde, N. R.

10.1101/171447 — biophysics — Posted on 2017-08-02

1405 New barcoded primers for efficient retrieval of cercozoan sequences in high-throughput environmental diversity surveys, with emphasis on worldwide biological soil crusts

Fiore-Donno, A. M.; Rixen, C.; Rippin, M.; Glaser, K.; Samolov, E.; Karsten, U.; Becker, B.; Bonkowski, M.

10.1101/171611 — bioinformatics — Posted on 2017-08-02

1406 FUN-LDA: A latent Dirichlet allocation model for predicting tissue-specific functional effects of noncoding variation

Backenroth, D.; He, Z.; Kiryluk, K.; Boeva, V.; Pethukova, L.; Khurana, E.; Christiano, A.; Buxbaum, J.; Ionita-Laza, I.

10.1101/069229 — bioinformatics — Posted on 2017-08-02

1407 Enhanced Pipeline ‘MetaGaAP-Py’ for the Analysis of Quasispecies and Non-Model Microbial Populations using Ultra-Deep ‘Meta-barcode’ Sequencing

Noune, C.; Hauxwell, C.

10.1101/171520 — bioinformatics — Posted on 2017-08-02

1408 Leveraging uncertainty information from deep neural networks for disease detection

Leibig, C.; Allken, V.; Berens, P.; Wahl, S.

10.1101/084210 — bioinformatics — Posted on 2017-08-02

1409 OptoGap: an optogenetics-enabled assay for quantification of cell-cell coupling in multicellular cardiac tissue

Yu, J.; Boyle, P. M.; Klimas, A.; Williams, J. C.; Trayanova, N. A.; Entcheva, E.

10.1101/171397 — bioengineering — Posted on 2017-08-02

1410 Multivariate association between single-nucleotide polymorphisms in Alzgene linkage regions and structural changes in the brain: discovery, refinement and validation

Szefer, E.; Lu, D.; Nathoo, F.; Beg, M. F.; Graham, J.; Alzheimer's Disease Neuroimaging Initiative,

10.1101/088310 — neuroscience — Posted on 2017-08-02

1411 Detection of live mycobacteria with a solvatochromic trehalose probe for point-of-care tuberculosis diagnosis

Kamariza, M.; Shieh, P.; Rodriguez-Rivera, F. P.; Ealand, C. S.; Chu, B.; Martinson, N.; Kana, B. D.; Bertozzi, C. R.

10.1101/171553 — microbiology — Posted on 2017-08-02

1412 A Central Limit Theorem for Punctuated Equilibrium

Bartoszek, K.

10.1101/039867 — evolutionary biology — Posted on 2017-08-02

1413 Oasis2.0: improved online analysis of small RNA-seq data

Rahman, R.-U.; Gautam, A.; Bethune, J.; Sattar, A.; Fiosins, M.; Magruder, D. S.; Capece, V.; Shomroni, O.; Bonn, S.

10.1101/170738 — bioinformatics — Posted on 2017-08-01

1414 Transferring and Generalizing Deep-Learning-based Neural Encoding Models across Subjects

Wen, H.; Shi, J.; Chen, W.; Liu, Z.

10.1101/171017 — neuroscience — Posted on 2017-08-01

1415 Triple dissociation of attention and decision computations across prefrontal cortex

Hunt, L. T.; Malalasekera, W. M. N.; de Berker, A. O.; Miranda, B.; Farmer, S. F.; Behrens, T. E. J.; Kennerley, S. W.

10.1101/171173 — neuroscience — Posted on 2017-08-01

1416 Extracranial estimation of neural mass model parameters using the Unscented Kalman Filter

Escuain-Poole, L.; Garcia-Ojalvo, J.; Pons Rivero, A. J.

10.1101/171207 — neuroscience — Posted on 2017-08-01

1417 Human placental syncytiotrophoblasts restrict Toxoplasma gondii vertical transmission at two distinct stages and induce CCL22 in response to infection

Ander, S.; Rudzki, E.; Arora, N.; Sadovsky, Y.; Coyne, C. B.; Boyle, J. P.

10.1101/170944 — microbiology — Posted on 2017-08-01

1418 A Tetratricopeptide Repeat Protein Regulates Carotenoid Biosynthesis and Chromoplast Development in Monkeyflowers (Mimulus)

Stanley, L. E.; Ding, B.; Sun, W.; Mou, F.; Hill, C.; Chen, S.; Yuan, Y.-W.

10.1101/171249 — genetics — Posted on 2017-08-01

1419 Endosymbiont diversity and evolution across the weevil tree of life

Zhang, G.; Browne, P.; Zhen, G.; Johnston, A.; Cadillo-Quiroz, H.; Franz, N.

10.1101/171181 — evolutionary biology — Posted on 2017-08-01

1420 Kernel multitask regression for toxicogenetics

Bernard, E.; Jiao, Y.; Scornet, E.; Stoven, V.; Walter, T.; Vert, J.-P.

10.1101/171298 — bioinformatics — Posted on 2017-08-01

1421 TRuML: A Translator for Rule-Based Modeling Languages

Suderman, R.; Hlavacek, W. S.

10.1101/171306 — systems biology — Posted on 2017-08-01

1422 Distress tolerance across self-report, behavioral and psychophysiological domains in women with eating disorders and healthy controls

Yiu, A.; Christensen, K.; Chen, E.

10.1101/170217 — physiology — Posted on 2017-08-01

1423 Development of subcortical volumes across adolescence in males and females: A multisample study of longitudinal changes

Herting, M. M.; Johnson, C.; Mills, K. L.; Vijayakumar, N.; Dennison, M.; Liu, C.; Goddings, A.-L.; Dahl, R. E.; Sowell, E. R.; Whittle, S.; Allen, N. B.; Tamnes, C. K.

10.1101/171389 — neuroscience — Posted on 2017-08-01

1424 The intrinsically disordered C-terminal linker of FtsZ regulates protofilament dynamics and superstructure in vitro

Sundararajan, K.; Goley, E. D.

10.1101/171280 — microbiology — Posted on 2017-08-01

1425 Genome-reconstruction for eukaryotes from complex natural microbial communities

West, P. T.; Probst, A. J.; Grigoriev, I. V.; Thomas, B. C.; Banfield, J. F.

10.1101/171355 — genomics — Posted on 2017-08-01

1426 Unexpected variation across mitochondrial gene trees and evidence for systematic error: How much gene tree variation is biological?

Richards, E. J.; Brown, J. M.; Barley, A. J.; Chong, R. A.; Thomson, R. C.

10.1101/171413 — evolutionary biology — Posted on 2017-08-01

1427 Weak interactions between groups and physical drivers of community dynamics in coastal phytoplankton

Barraquand, F.; Picoche, C.; Maurer, D.; Carassou, L.; Auby, I.

10.1101/171264 — ecology — Posted on 2017-08-01

1428 Learning causal biological networks with generalized Mendelian randomization

Badsha, M. B.; Fu, A. Q.

10.1101/171348 — bioinformatics — Posted on 2017-08-01

1429 QuimP - Analyzing transmembrane signalling in highly deformable cells

Baniukiewicz, P.; Collier, S.; Bretschneider, T.

10.1101/171199 — bioinformatics — Posted on 2017-08-01

1430 Exploration and generalization in vast spaces

Wu, C. M.; Schulz, E.; Speekenbrink, M.; Nelson, J. D.; Meder, B.

10.1101/171371 — animal behavior and cognition — Posted on 2017-08-01

1431 The geometry of heterosis

Fievet, J. B.; Nidelet, T.; Dillmann, C.; de Vienne, D.

10.1101/170902 — systems biology — Posted on 2017-08-01

1432 Cftr Modulates Wnt/β-Catenin Signaling and Stem Cell Proliferation in Murine Intestine

Strubberg, A. M.; Liu, J.; Walker, N. M.; Stefanski, C. D.; MacLeod, R. J.; Magness, S. T.; Clarke, L. L.

10.1101/156562 — physiology — Posted on 2017-08-01

1433 Experience-dependent translational state defined by cell type-specific ribosome profiling

Eacker, S. M.; Crawford, K.; Brichta, L.; Riessland, M.; Ingolia, N. T.; Greengard, P.; Dawson, T. M.; Dawson, V. L.

10.1101/169425 — genomics — Posted on 2017-08-01

1434 Male-driven reinforcement and cascade reinforcement in darters

Moran, R. L.; Fuller, R. C.

10.1101/171231 — evolutionary biology — Posted on 2017-08-01

1435 Local and population-level responses of Greater Sage-Grouse to oil and gas and climatic variation in Wyoming

Ramey, R. R.; Thorley, J. L.; Ivey, A. S.

10.1101/028274 — ecology — Posted on 2017-08-01

1436 How Many Females Are There? Cheating and Female Dispersion Can Explain Mating Behavior Evolution

Valerio Gomes, B.; Menezes Guimaraes, D.; Szczupak, D.; Neves, K.

10.1101/171330 — ecology — Posted on 2017-08-01

1437 Sugar intake elicits a small-scale search behavior in flies and honey bees that involves capabilities found in large-scale navigation

Brockmann, A.; Murata, S.; Murashima, N.; Boyapati, R. K.; Shakeel, M.; Prabhu, N. G.; Herman, J. J.; Basu, P.; Tanimura, T.

10.1101/171215 — animal behavior and cognition — Posted on 2017-08-01

1438 Category learning biases sensory representations in visual cortex.

Ester, E. F.; Sprague, T. C.; Serences, J. T.

10.1101/170845 — neuroscience — Posted on 2017-08-01

1439 Rapid changes in Atlantic grey seal milk from birth to desertion

Lowe, A. D.; Bawazeer, S.; Watson, D. G.; McGill, S.; Burchmore, R. J. S.; Pomeroy, P. P.; Kennedy, M. W.

10.1101/170514 — zoology — Posted on 2017-08-01

1440 Microbiome-host systems interactions: Protective effects of propionate upon the blood-brain barrier

Hoyles, L.; Snelling, T.; Umlai, U.-K.; Nicholson, J. K.; Carding, S. R.; Glen, R. C.; McArthur, S.

10.1101/170548 — neuroscience — Posted on 2017-08-01

1441 Category learning biases sensory representations in visual cortex.

Ester, E. F.; Sprague, T. C.; Serences, J. T.

10.1101/170845 — neuroscience — Posted on 2017-08-01

1442 Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

Howard, D. M.; Adams, M. J.; Shirali, M.; Clarke, T.-K.; Marioni, R. E.; Davies, G.; Coleman, J. R. I.; Alloza, C.; Shen, X.; Barbu, M. C.; Wigmore, E. M.; Gibson, J.; Hagenaars, S.; Lewis, C. M.; Smith, D. J.; Sullivan, P. F.; Haley, C. S.; Breen, G.; Deary, I. J.; McIntosh, A. M.

10.1101/168732 — genetics — Posted on 2017-08-01

1443 Live imaging of heart tube development in mouse reveals alternating phases of cardiac differentiation and morphogenesis

Ivanovitch, K.; Temino, S.; Torres, M.

10.1101/170522 — developmental biology — Posted on 2017-08-01

1444 BGP: Branched Gaussian processes for identifying gene-specific branching dynamics in single cell data

Boukouvalas, A.; Hensman, J.; Rattray, M.

10.1101/166868 — bioinformatics — Posted on 2017-08-01

1445 Feel the way with a vibrotactile compass: Does a navigational aid aid navigation?

Weisberg, S. M.; Badgio, D.; Chatterjee, A.

10.1101/122994 — animal behavior and cognition — Posted on 2017-08-01

1446 Widespread population variability of intron size in evolutionary old genes: implications for gene expression variability

Rigau, M.; Juan, D.; Valencia, A.; Rico, D.

10.1101/171165 — genomics — Posted on 2017-08-01

1447 The validity of the coalescent approximation for large samples

Melfi, A.; Viswanath, D.

10.1101/170928 — genetics — Posted on 2017-08-01

1448 Doubling healthy lifespan using drug synergies

Dessale, T.; Batchu, K. C.; Barardo, D.; Ng, L. F.; Lam, V. Y. M.; Xiao, L.; Wenk, M. R.; Tolwinski, N. S.; Gruber, J.

10.1101/153205 — biochemistry — Posted on 2017-08-01

1449 Integrated time-course omics analysis distinguishes immediate therapeutic response from acquired resistance

Stein-O'Brien, G.; Kagohara, L. T.; Li, S.; Thakar, M.; Ranaweera, R.; Ozawa, H.; Cheng, H.; Considine, M.; Favorov, A.; Danilova, L.; Califano, J. A.; Izumchenko, E.; Gaykalova, D. A.; Chung, C. H.; Fertig, E. J.