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Archive, 2020-10

8 Structure of Gcn1 bound to stalled and colliding 80S ribosomes
Pochopien, A. A.; Beckert, B.; Kasvandik, S.; Berninghausen, O.; Beckmann, R.; Tenson, T.; Wilson, D. N.
10.1101/2020.10.31.363135 — biochemistry — Posted on 2020-10-31
10 HP1 proteins compact DNA into mechanically and positionally stable phase separated domains
Keenen, M. M.; Brown, D.; Brennan, L. D.; Renger, R.; Khoo, H.; Carlson, C. R.; Huang, B.; Grill, S. W.; Narlikar, G. J.; Redding, S.
10.1101/2020.10.30.362772 — biochemistry — Posted on 2020-10-31
20 Phylogenomics reveals that Asaia symbionts from insects underwent convergent genome reduction, preserving an insecticide-degrading gene
Comandatore, F.; Damiani, C.; Cappelli, A.; Martins Ribolla, P. E.; Gasperi, G.; Gradoni, F.; Capelli, G.; Piazza, A.; Montarsi, F.; Mancini, M. V.; Rossi, P.; Ricci, I.; Bandi, C.; Favia, G.
10.1101/2020.10.30.363036 — microbiology — Posted on 2020-10-31
21 Neuroplasticity associated with conversational turn-taking following a family-based intervention
Romeo, R. R.; Leonard, J. A.; Grotzinger, H. M.; Robinson, S. T.; Takada, M. E.; Mackey, A. P.; Scherer, E.; Rowe, M. L.; West, M. R.; Gabrieli, J. D. E.
10.1101/2020.10.30.362723 — neuroscience — Posted on 2020-10-31
23 Tumor-educated monocyte-dendritic progenitors promote a metastatic switch
Magidey-Klein, K.; Klever, K.; Cooper, T. J.; Normand, R.; Zhang, T.; Timaner, M.; Raviv, Z.; James, B.; Gazit, R.; Ronai, Z. A.; Shen-Orr, S. S.; Shaked, Y.
10.1101/2020.08.25.266189 — cancer biology — Posted on 2020-10-31
24 Frequent loss-of-heterozygosity in CRISPR-Cas9-edited early human embryos
Alanis-Lobato, G.; Zohren, J.; McCarthy, A.; Fogarty, N. M. E.; Kubikova, N.; Hardman, E.; Greco, M.; Wells, D.; Turner, J. M. A.; Niakan, K.
10.1101/2020.06.05.135913 — developmental biology — Posted on 2020-10-31
25 Chromosomally unstable tumor cells specifically require KIF18A for proliferation
Marquis, C.; Fonseca, C. L.; Queen, K. A.; Wood, L.; Vandal, S. E.; Malaby, H. L.; Clayton, J. E.; Stumpff, J.
10.1101/2020.06.18.159327 — cell biology — Posted on 2020-10-31
26 Infra-slow modulation of fast beta/gamma oscillations in the mouse visual system.
Orlowska-Feuer, P.; Allen, A. E.; Brown, T. M.; Szkudlarek, H. J.; Lucas, R. J.; Storchi, R.
10.1101/2020.02.24.963124 — neuroscience — Posted on 2020-10-31
29 Flapjack: a data management and analysis tool for genetic circuit characterization
Yanez Feliu, G.; Earle Gomez, B.; Berrocal, V. C.; Munoz Silva, M.; Nunez, I. N.; Matute, T. F.; Arce Medina, A.; Vidal, G.; Vidal Cespedes, C.; Dahlin, J.; Federici, F.; Rudge, T. J.
10.1101/2020.10.30.362244 — synthetic biology — Posted on 2020-10-31
31 UCSC Cell Browser: Visualize Your Single-Cell Data
Speir, M. L.; Bhaduri, A.; Markov, N. S.; Moreno, P.; Nowakowski, T. J.; Papatheodorou, I.; Pollen, A. A.; Seninge, L.; Kent, W. J.; Haeussler, M.
10.1101/2020.10.30.361162 — bioinformatics — Posted on 2020-10-31
34 The evolution of social learning as phenotypic cue integration
Kuijper, B.; Leimar, O.; Hammerstein, P.; McNamara, J. M.; Dall, S. R. X.
10.1101/2020.10.30.358028 — evolutionary biology — Posted on 2020-10-31
36 CLOCK/BMAL1 interferes with segmentation clock oscillation in mouse embryonic organoids
Umemura, Y.; Koike, N.; Tsuchiya, Y.; Watanabe, H.; Kondoh, G.; Kageyama, R.; Yagita, K.
10.1101/2020.10.30.362830 — developmental biology — Posted on 2020-10-31
38 Molecular mechanisms of LC3-associated phagocytosis in the macrophage response to Paracoccidioides spp.
Oliveira, G. P. d.; Sousa, H. R. d.; Gorgonha, K. C. d. M.; Borges, T. K. d. S.; Rangel, K. T.; Fabricant, S.; Gustavo, F. C. K.; Albuquerque, L. F. F.; Rossi, A.; Hurtado, F. A.; Paes, H. C.; Casadevall, A.; Silva-Pereira, I.; Albuquerque, P.; Felipe, M. S. S.; Nicola, A. M.
10.1101/2020.10.30.362681 — immunology — Posted on 2020-10-31
39 Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells
Sumida, T. S.; Dulberg, S.; Schupp, J.; Stillwell, H. A.; Axisa, P.-P.; Comi, M.; Lincoln, M.; Unterman, A.; Kaminski, N.; Madi, A.; Kuchroo, V. K.; Hafler, D. A.
10.1101/2020.10.30.362947 — immunology — Posted on 2020-10-31
46 Microbiome of the Black Sea water column analyzed by genome centric metagenomics
Cabello-Yeves, P. J.; Callieri, C.; Picazo, A.; Mehrshad, M.; Haro-Moreno, J. M.; Roda-Garcia, J. J.; Dzhembekova, N.; Slabakova, V.; Slabakova, N.; Moncheva, S.; Rodriguez-Valera, F.
10.1101/2020.10.30.362129 — microbiology — Posted on 2020-10-30
47 Protective Antibodies Against Human Parainfluenza Virus Type 3 (HPIV3) Infection
Boonyaratanakornkit, J.; Singh, S.; Weidle, C.; Rodarte, J.; Bakthavatsalam, R.; Perkins, J.; Stewart-Jones, G. B. E.; Kwong, P. D.; McGuire, A. T.; Pancera, M.; Taylor, J. J.
10.1101/2020.06.15.153478 — immunology — Posted on 2020-10-30
48 Non-canonical Activation of Human Group 2 Innate Lymphoid Cells by TLR4 Signaling
She, L.; Alanazi, H. H.; Wang, J.; Chupp, D. P.; Xu, Y.; Zan, H.; Xu, Z.; Sun, Y.; Xiong, N.; Zhang, N.; Zhang, X.; Liu, Y.; Li, X.-D.
10.1101/2020.10.29.361345 — immunology — Posted on 2020-10-30
49 Prototypical oncogene family Myc defines unappreciated distinct lineage states of small cell lung cancer
Patel, A. S.; Yoo, S.; Kong, R.; Sato, T.; Sinha, A.; Karam, S.; Bao, L.; Fridrikh, M.; Emoto, K.; Nudelman, G.; Powell, C. A.; Beasley, M. B.; Zhu, J.; Watanabe, H.
10.1101/852939 — cancer biology — Posted on 2020-10-30
52 What the Phage: A scalable workflow for the identification and analysis of phage sequences
Marquet, M.; Hölzer, M.; Pletz, M. W.; Viehweger, A.; Makarewicz, O.; Ehricht, R.; Brandt, C.
10.1101/2020.07.24.219899 — bioinformatics — Posted on 2020-10-30
56 Integrated analysis of high throughput transcriptomic data revealed specific gene expression signature of cardiomyocytes
Omrani, M. R.; Sharifi, E.; Khazaei, N.; Jahangiri Esfahani, S.; Kieran, N. W.; Hashemi, H.; Mohammadnia, A.; Yaqubi, M.
10.1101/2020.06.14.151399 — cell biology — Posted on 2020-10-30
57 Transcriptome and Chromatin Landscape of iNKT cells are Shaped by Subset Differentiation and Antigen Exposure
Murray, M. P.; Engel, I.; Seumois, G.; de la Mata, S. H.; Rosales, S. L.; Sethi, A.; Premlal, A. L. R.; Seo, G.-Y.; Greenbaum, J.; Vijayanand, P.; Scott-Browne, J. P.; Kronenberg, M.
10.1101/2020.10.27.357673 — immunology — Posted on 2020-10-30
61 Aberrant Ca2+ homeostasis in adipocytes links inflammation to metabolic dysregulation in obesity
Guney, E.; Arruda, A. P.; Parlakgul, G.; Cagampan, E.; Min, N.; Lee, Y.; Greene, L.; Tsaousidou, E.; Inouye, K.; Han, M. S.; Davis, R. J.; Hotamisligil, G. S.
10.1101/2020.10.28.360008 — physiology — Posted on 2020-10-30
69 Compressed sensing for imaging transcriptomics
Cleary, B.; Simonton, B.; Bezney, J.; Murray, E.; Alam, S.; Sinha, A.; Habibi, E.; Marshall, J.; Lander, E. S.; Chen, F.; Regev, A.
10.1101/743039 — molecular biology — Posted on 2020-10-30
70 Ribosome-linked mRNA-rRNA chimeras reveal active novel virus-host associations.
Ignacio-Espinoza, J. C.; Laperriere, S.; Yeh, Y.-C.; Weissman, J.; Hou, S.; Long, A.; Fuhrman, J. A.
10.1101/2020.10.30.332502 — microbiology — Posted on 2020-10-30
71 Fine Molecular Tuning of Chimeric Antigen Receptors through Hinge Length Optimization
McComb, S.; Nguyen, T.; Henry, K. A.; Bloemberg, D.; Maclean, S.; Gilbert, R.; Gadoury, C.; Pon, R.; Sulea, T.; Zhu, Q.; Weeratna, R. D.
10.1101/2020.10.30.360925 — immunology — Posted on 2020-10-30
72 Using a betting game to reveal the rich nature of visual working memories
Jabar, S. B.; Sreenivasan, K. K.; Lentzou, S.; Kanabar, A.; Brady, T. F.; Fougnie, D.
10.1101/2020.10.28.357442 — neuroscience — Posted on 2020-10-30
73 Behavioral and neural variability of naturalistic arm movements
Peterson, S. M.; Singh, S. H.; Wang, N. X. R.; Rao, R. P. N.; Brunton, B. W.
10.1101/2020.04.17.047357 — neuroscience — Posted on 2020-10-30
75 The role of the meningeal lymphatic system in local inflammation and trigeminal nociception implicated in migraine pain
Mikhailov, N.; Koroleva, K.; Abdollahzadeh, A.; Giniatullina, R.; Gafurov, O.; Malm, T.; Sierra Lopez, A.; Tohka, J.; Noe, F. M.; Giniatullin, R.
10.1101/2020.04.25.060939 — neuroscience — Posted on 2020-10-30
80 Sea anemone genomes reveal ancestral metazoan chromosomal macrosynteny
Zimmermann, B.; Robb, S. M. C.; Genikhovich, G.; Fropf, W. J.; Weilguny, L.; He, S.; Chen, S.; Lovegrove-Walsh, J.; Hill, E. M.; Ragkousi, K.; Praher, D.; Fredman, D.; Moran, Y.; Gibson, M. C.; Technau, U.
10.1101/2020.10.30.359448 — genomics — Posted on 2020-10-30
81 Metformin strongly affects gut microbiome composition in high-fat diet-induced type 2 diabetes mouse model of both sexes
Silamikele, L.; Silamikelis, I.; Ustinova, M.; Kalnina, Z.; Elbere, I.; Petrovska, R.; Kalnina, I.; Klovins, J.
10.1101/2020.10.30.362095 — microbiology — Posted on 2020-10-30
83 PRAK-03202: A triple antigen VLP vaccine candidate against SARS CoV-2
Mazumder, S.; Rastogi, R.; Undale, A.; Arora, K.; Arora, N. M.; Das Purkayastha, B. P.; Kumar, D.; Joseph, A.; Mali, B.; Arya, V. B.; Kalyanaraman, S.; Mukherjee, A.; Gupta, A.; Potdar, S.; Roy, S. S.; Parashar, D.; Paliwal, J.; Singh, S. K.; Naqvi, A.; Srivastava, A.; Singh, M. K.; Kumar, D.; Bansal, S.; Rautray, S.; Singh, I.; Fengade, P.; Kumar, B.; Saini, M.; Jain, K.; Gupta, R.; Kundu, P. K.
10.1101/2020.10.30.360115 — immunology — Posted on 2020-10-30
85 COVID Moonshot: Open Science Discovery of SARS-CoV-2 Main Protease Inhibitors by Combining Crowdsourcing, High-Throughput Experiments, Computational Simulations, and Machine Learning
The COVID Moonshot Consortium, ; Achdout, H.; Aimon, A.; Bar-David, E.; Barr, H.; Ben-Shmuel, A.; Bennett, J.; Bobby, M. L.; Brun, J.; BVNBS, S.; Calmiano, M.; Carbery, A.; Cattermole, E.; Chodera, J. D.; Clyde, A.; Coffland, J. E.; Cohen, G.; Cole, J.; Contini, A.; Cox, L.; Cvitkovic, M.; Dias, A.; Douangamath, A.; Duberstein, S.; Dudgeon, T.; Dunnett, L.; Eastman, P. K.; Erez, N.; Fairhead, M.; Fearon, D.; Fedorov, O.; Ferla, M.; Foster, H.; Foster, R.; Gabizon, R.; Gehrtz, P.; Gileadi, C.; Giroud, C.; Glass, W. G.; Glen, R.; Glinert, I.; Gorichko, M.; Gorrie-Stone, T.; Griffen, E. J.; Heer
10.1101/2020.10.29.339317 — biochemistry — Posted on 2020-10-30
87 Brilacidin, a COVID-19 Drug Candidate, Exhibits Potent In Vitro Antiviral Activity Against SARS-CoV-2
Bakovic, A.; Risner, K.; Bhalla, N.; Alem, F.; Chang, T. L.; Weston, W.; Harness, J. A.; Narayanan, A.
10.1101/2020.10.29.352450 — microbiology — Posted on 2020-10-30
91 The GhsrQ343X allele favors the storage of fat by acting on nutrient partitioning
Marion, C.; Zizzari, P.; Denis, R. G.; Hassouna, R.; Chebani, Y.; Le Pen, G.; Noble, F.; Luquet, S.; Pantel, J.
10.1101/2020.10.30.362343 — physiology — Posted on 2020-10-30
94 AI-guided discovery of the invariant host response to viral pandemics
Sahoo, D.; Katkar, G. D.; Khandelwal, S.; Behroozikhah, M.; Claire, A.; Castillo, V.; Tindle, C.; Fuller, M.; Taheri, S.; Rogers, T. F.; Beutler, N.; Ramirez, S.; Rawlings, S. A.; Pretorius, V.; Smith, D.; Burton, D. R.; Alexander, L. C.; Duran, J. M.; Crotty, S.; Dan, J. M.; Das, S.; Ghosh, P.
10.1101/2020.09.21.305698 — bioinformatics — Posted on 2020-10-30
95 Elucidating dynamics and regulation of alternative splicing in osteogenic differentiation
Wang, Y.; Chun, R. F.; Adhikari, S.; Lopez, C. M.; Henrich, M.; Yacoubian, V.; Lin, L.; Adams, J. S.; Xing, Y.
10.1101/2020.10.30.362384 — bioinformatics — Posted on 2020-10-30
97 A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells
Mellott, D.; Tseng, C.-T.; Drelich, A.; Fajtova, P.; Chenna, B. C.; Kostomiris, D.; Hsu, J. C.; Zhu, J.; Taylor, Z.; Tat, V.; Katzfuss, A.; Li, L.; Giardini, M. A.; Skinner, D.; Hirata, K.; Beck, S.; Carlin, A. F.; Clark, A. E.; Berreta, L.; Maneval, D.; Frueh, F.; Hurst, B. L.; Wang, H.; Kocurek, K. I.; Raushel, F. M.; O'Donoghue, A.; Siqueira-Neto, J. L.; Meek, T. D.; McKerrow, J. H.
10.1101/2020.10.23.347534 — biochemistry — Posted on 2020-10-30
98 Global regulatory transitions at core promoters demarcate the mammalian germline cycle
Cvetesic, N.; Borkowska, M.; Hatanaka, Y.; Leitch, H. G.; Mueller, F.; Yu, C.; Vincent, S. D.; Tora, L.; Hajkova, P.; Lenhard, B.
10.1101/2020.10.30.361865 — developmental biology — Posted on 2020-10-30
100 NFAT are Essential and Redundant Actors for Leukemia Initiating Potential in T-cell Acute Lymphoblastic Leukemia
Catherinet, C.; Passaro, D.; Gachet, S.; Medyouf, H.; Reynaud, A.; Lasgi, C.; Ghysdael, J.; Tran Quang, C.
10.1101/2020.10.30.362376 — cancer biology — Posted on 2020-10-30
103 Genomic diversity and antimicrobial resistance among non-typhoidal Salmonella associated with human disease in The Gambia
Darboe, S.; Bradbury, R. S.; Phelan, J.; Kanteh, A.; Muhammad, A.-K.; Worwui, A.; Yang, S.; Nwakanma, D.; Perez-Sepulveda, B.; Kariuki, S.; Kwambana-Adams, B. A.; Antonio, M.
10.1101/2020.10.30.316588 — genomics — Posted on 2020-10-30
104 Archaeogenomic Distinctiveness of the Isthmo-Colombian Area
Capodiferro, M. R.; Aram, B.; Raveane, A.; Rambaldi Migliore, N.; Colombo, G.; Ongaro, L.; Rivera, J.; Mendizabal, T.; Hernandez-Mora, I.; Tribaldos, M.; Perego, U. A.; Li, H.; Scheib, C. L.; Modi, A.; Gomez-Carballa, A.; Grugni, V.; Lombardo, G.; Hellenthal, G.; Pascale, J. M.; Bertolini, F.; Grieco, G.; Cereda, C.; Lari, M.; Caramelli, D.; Pagani, L.; Metspalu, M.; Knipper, C.; Friedrich, R.; Olivieri, A.; Salas, A.; Cooke, R.; Torroni, A.; Montinaro, F.; Motta, J.; Martin, J. G.; Semino, O.; Malhi, R. S.; Achilli, A.
10.1101/2020.10.30.350678 — genomics — Posted on 2020-10-30
105 European Primary Forest Database (EPFD) v2.0
Sabatini, F. M.; Bluhm, H.; Kun, Z.; Aksenov, D.; Atauri, J. A.; Buchwald, E.; Burrascano, S.; Cateau, E.; Diku, A.; Marques Duarte, I.; Fernandez Lopez, A. B.; Garbarino, M.; Grigoriadis, N.; Horvath, F.; Keren, S.; Kitenberga, M.; Kis, A.; Kraut, A.; Ibisch, P. L.; Larrieu, L.; Lombardi, F.; Matovic, B.; Melu, R. N.; Meyer, P.; Midteng, R.; Mikac, S.; Mikolas, M.; Mozgeris, G.; Panayotov, M.; Pisek, R.; Nunes, L.; Ruete, A.; Schickhofer, M.; Simovski, B.; Stillhard, J.; Stojanovic, D.; Szwagrzyk, J.; Tikkanen, O.-P.; Toromani, E.; Volosyanchuk, R.; Vrska, T.; Waldherr, M.; Yermokhin, M.; Zla
10.1101/2020.10.30.362434 — ecology — Posted on 2020-10-30
106 Enhancing lifespan of budding yeast by pharmacological lowering of amino acid pools
Hepowit, N. L.; Macedo, J. K. A.; Young, L. E. A.; Liu, K.; Sun, R. C.; MacGurn, J.; Dickson, R. C.
10.1101/2020.10.30.362459 — cell biology — Posted on 2020-10-30
114 Combining functional and structural genomics to track antibiotic resistance genes in mobile elements in clinical bacterial strains
Borelli, T. C.; Lovate, G. L.; Scaranello, A. F. T.; Ribeiro, L. F.; Zaramela, L.; Pereira-dos-Santos, F. M.; Guazzaroni, M. E.; Silva-Rocha, R.
10.1101/2020.10.30.361923 — microbiology — Posted on 2020-10-30
115 Imperfect innate immune antagonism renders SARS-CoV-2 vulnerable towards IFN-γ and -{lambda}
Hayn, M.; Hirschenberger, M.; Koepke, L.; Straub, J. H.; Nchioua, R.; Christensen, M. H.; Klute, S.; Prelli Bozzo, C.; Aftab, W.; Zech, F.; Conzelmann, C.; Mueller, J. A.; Srinivasachar Badarinarayan, S.; Stuerzel, C. M.; Forne, I.; Stenger, S.; Conzelmann, K.-K.; Muench, J.; Sauter, D.; Schmidt, F. I.; Imhof, A.; Kirchhoff, F.; Sparrer, K. M. J.
10.1101/2020.10.15.340612 — microbiology — Posted on 2020-10-30
116 The effects of CSTB duplication on APP/amyloid-β pathology and cathepsin activity in a mouse model
Wu, Y.; Whittaker, H. T.; Noy, S.; Cleverley, K.; Brault, V.; Herault, Y.; Fisher, E. M. C.; Wiseman, F. K.
10.1101/2020.10.30.362004 — neuroscience — Posted on 2020-10-30
117 Open Science Saves Lives: Lessons from the COVID-19 Pandemic
Besancon, L.; Peiffer-Smadja, N.; Segalas, C.; Jiang, H.; Masuzzo, P.; Smout, C. A.; Billy, E.; Deforet, M.; Leyrat, C.
10.1101/2020.08.13.249847 — scientific communication and education — Posted on 2020-10-30
118 Assessment of transparency indicators across the biomedical literature: how open is open?
Serghiou, S.; Contopoulos-Ioannidis, D. G.; Boyack, K. W.; Riedel, N.; Wallach, J. D.; Ioannidis, J. P. A.
10.1101/2020.10.30.361618 — scientific communication and education — Posted on 2020-10-30
119 An evolutionary conserved lysine acetylation hotspot regulates plant mitochondrial malate dehydrogenase activity
Balparda, M.; Elsässer, M.; Badia, M.; Giese, J.; Hüdig, M.; Reinmuth, L.; Schwarzländer, M.; Finkemeier, I.; Schallenberg-Rüdinger, M.; Maurino, V. G.
10.1101/2020.10.30.362046 — plant biology — Posted on 2020-10-30
120 Lyve-1 expressing perivascular macrophages orchestrate pericyte expansion to sustain angiogenesis in cancer
Opzoomer, J. W.; Anstee, J. E.; Dean, I.; Hill, E. J.; Bouybayoune, I.; Caron, J.; Muliaditan, T.; Gordon, P.; Nuamah, R.; Pinder, S. E.; Ng, T.; Dazzi, F.; Kordasti, S.; Withers, D. R.; Lawrence, T.; Arnold, J. N.
10.1101/2020.10.30.361907 — cancer biology — Posted on 2020-10-30
121 Reproductive history determines ErbB2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model
Ordonez, L. D.; Melchor, L.; Greenow, K. R.; Kendrick, H.; Tornillo, G.; Bradford, J.; Giles, P.; Smalley, M. J.
10.1101/2020.10.30.361998 — cancer biology — Posted on 2020-10-30
122 The genomic epidemiology of SARS-CoV-2 in Palestine
Qutob, N.; Salah, Z.; Richard, D.; Darwish, H.; Sallam, H.; Shtayeh, I.; Najjar, O.; Balloux, F.; van Dorp, L.
10.1101/2020.10.26.355677 — genomics — Posted on 2020-10-30
124 Value Shapes Abstraction During Learning
Cortese, A.; Yamamoto, A.; Hashemzadeh, M.; Sepulveda, P.; Kawato, M.; De Martino, B.
10.1101/2020.10.29.361469 — neuroscience — Posted on 2020-10-30
125 Increasing Grain Yield in Bread Wheat by Selection for High Spike Fertility Index
Pontaroli, A. C.; Alonso, M. P.; Mirabella, N. E.; Panelo, J. S.; Franco, M. F.; Vanzetti, L. S.; Lorenzo, M.
10.1101/2020.10.30.361782 — plant biology — Posted on 2020-10-30
127 How many and which species to plant? A multi-trait-based approach to select species to restore ecosystem services
Tsujii, P. K.; Coutinho, A. G.; Medina, A. M.; Kraft, N. J. B.; Gonzalez-Melo, A.; Higuchi, P.; Muller, S. C.; Niinemets, U.; Pillar, V. D.; Sosinski, E. E.; Carlucci, M. B.
10.1101/2020.10.29.359455 — ecology — Posted on 2020-10-30
128 A KDM4A-PAF1-mediated epigenomic network is essential for acute myeloid leukemia cell self-renewal and survival
Massett, M. E.; Monaghan, L.; Patterson, S. D.; Mannion, N.; Bunschoten, R. P.; Hoose, A.; Marmiroli, S.; Liskamp, R. M.; Jorgensen, H. G.; Vetrie, D.; Michie, A. M.; Huang, X.
10.1101/2020.10.30.361881 — cancer biology — Posted on 2020-10-30
129 MITF Isoforms- Insights from an RNA-Seq study
Kirty, K.; Sigurdsson, S.; Gudjonsson, T.; Einarsdottir, B. O.; Sigurdsson, S.
10.1101/2020.10.22.351031 — genomics — Posted on 2020-10-30
131 Punctuated loci on chromosome IV determine natural variation in Orsay virus susceptibility of Caenorhabditis elegans strains Bristol N2 and Hawaiian CB4856
Sterken, M. G.; van Sluijs, L.; Wang, Y. A.; Ritmahan, W.; Gultom, M. L.; Riksen, J. A. G.; Volkers, R. J. M.; Snoek, B. L.; Pijlman, G. P.; Kammenga, J.
10.1101/2020.10.30.361683 — genetics — Posted on 2020-10-30
134 Disentangling metacommunity processes using multiple metrics in space and time
Guzman, L. M.; Thompson, P. L.; Viana, D. S.; Vanschoenwinkel, B. J.; Horvath, Z.; Ptacnik, R.; Jeliazkov, A.; Gascon, S.; Lemmens, P.; Anton-Pardo, M. T.; Langenheder, S.; De Meester, L.; Chase, J.
10.1101/2020.10.29.361303 — ecology — Posted on 2020-10-30
137 Primary cilia formation does not rely on WNT/β-catenin signaling
Bernatik, O.; Paclikova, P.; Kotrbova, A.; Bryja, V.; Cajanek, L.
10.1101/2020.10.30.361642 — cell biology — Posted on 2020-10-30
139 Method comparison studies of telomere length measurement using qPCR approaches: a critical appraisal of the literature
Lindrose, A. R.; McLester-Davis, L. W. Y.; Tristano, R. I.; Kataria, L.; Gadalla, S. M.; Eisenberg, D. T. A.; Verhulst, S.; Drury, S.
10.1101/2020.09.04.282632 — molecular biology — Posted on 2020-10-30
141 Human cerebral cortex networks use expanding and contracting state dynamic to shape cortical functions
Willumsen, A.; Midtgaard, J.; Jespertsen, B.; Hansen, C. K. K.; Lam, S. N.; Hansen, S.; Kupers, R.; Fabricius, M. E.; Litman, M.; Pinborg, L.; Tascon-Vidarte, J. D.; Sabers, A.; Roland, P. E.
10.1101/2020.09.24.309468 — neuroscience — Posted on 2020-10-30
142 Differential patterns of gyral and sulcal morphological changes during normal aging process
Lin, H.-Y.; Huang, C.-C.; Chou, K.-H.; Yang, A. C.; Lo, C.-Y. Z.; Tsai, S.-J.; Lin, C.-P.
10.1101/2020.10.30.361626 — neuroscience — Posted on 2020-10-30
143 Using temperature to analyse the neural basis of a latent temporal decision
Monteiro, T.; Rodrigues, F. S.; Pexirra, M.; Cruz, B. F. P.; Goncalves, A. I.; Rueda-Orozco, P. E.; Paton, J. J.
10.1101/2020.08.24.251827 — neuroscience — Posted on 2020-10-30
144 A prospective longitudinal study shows putamen volume is associated with moderate amphetamine use and resultant cognitive impairments
Kendrick, K. M.; Daumann, J.; Wagner, D.; Koester, P.; Tittgemeyer, M.; Luo, Q.; Gouzoulis-Mayfrank, E.; Becker, B.
10.1101/2020.10.29.361378 — neuroscience — Posted on 2020-10-30
146 Ethanol's action at BK channels accelerates the transition from moderate to excessive alcohol consumption
Okhuarobo, A.; Kreifeldt, M.; Bhattacharyya, P.; Dopico, A. M.; Roberts, A. J.; Homanics, G. E.; Contet, C.
10.1101/2020.10.29.360107 — neuroscience — Posted on 2020-10-30
149 Two decades of creating drought tolerant maize and underpinning prediction technologies in the US corn-belt: Review and perspectives on the future of crop design
Messina, C.; Cooper, M.; Hammer, G.; Berning, D.; Ciampitti, I.; Clark, R.; Diepenbrock, C. H.; Gho, C.; Jines, M.; Lee, T.; McCormick, R. F.; Mihura, E.; Podlich, D.; Rotundo, J.; Smalley, M.; Tang, T.; Truong, S.; van Eeuwijk, F.
10.1101/2020.10.29.361337 — plant biology — Posted on 2020-10-30
150 PHYTOCHROMES B1/B2 ARE KEY REGULATORS OF EPIGENOME REPROGRAMMING DURING TOMATO FRUIT DEVELOPMENT
Bianchetti, R.; Bellora, N.; de Haro, L.; Zuccarelli, R.; Rosado, D.; Freschi, L.; Rossi, M.; Bermudez, L. F.
10.1101/2020.07.30.227447 — plant biology — Posted on 2020-10-30
151 Trpm8 modulates thermogenesis in a sex-dependent manner without influencing cold-induced bone loss
Lelis Carvalho, A.; Treyball, A.; Brooks, D. J.; Costa, S.; Neilson, R. J.; Reagan, M. R.; Bouxsein, M. L.; Motyl, k.
10.1101/2020.03.18.996694 — physiology — Posted on 2020-10-30
152 The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma
Boone, M. A.; Taslim, C.; Crow, J. C.; Selich-Anderson, J.; Showpnil, I. A.; Sunkel, B. D.; Wang, M.; Stanton, B. Z.; Theisen, E. R.; Lessnick, S. L.
10.1101/2020.10.29.355859 — cancer biology — Posted on 2020-10-30
153 Irradiated mesenchymal stromal cells induce genetic instability in human CD34+ cells
Popp, H. D.; Kohl, V.; Drews, O.; Costina, V.; Bierbaum, M.; Jawhar, A.; Roehl, H.; Weiss, C.; Brendel, S.; Kleiner, H.; Flach, J.; Spiess, B.; Seifarth, W.; Nowak, D.; Hofmann, W.-K.; Fabarius, A.
10.1101/2020.10.30.361758 — cancer biology — Posted on 2020-10-30
154 Myeloid derived Oncostatin M reprogrammes cancer-associated fibroblasts and tumour cells promoting breast cancer progression
Araujo, A. M.; Abaurrea, A.; Azcoaga, P.; Lopez-Velazco, J. I.; Rezola, R.; Osorio-Querejeta, I.; Valdes-Mora, F.; Flores, J. M.; Jenkins, L.; Fernandez-Nogueira, P.; Ferrari, N.; Martin-Martin, N.; Tzankov, A.; Eppenberger-Castori, S.; Alvarez-Lopez, I.; Urruticoechea, A.; Bragado, P.; Coleman, N.; Carracedo, A.; Gallego-Ortega, D.; Calvo, F.; Isacke, C. M.; Caffarel, M. M.; Lawrie, C. H.
10.1101/2020.10.30.356774 — cancer biology — Posted on 2020-10-30
156 Combined fluorescence, optical diffraction tomography and Brillouin microscopy
Schlüssler, R.; Kim, K.; Nötzel, M.; Taubenberger, A. V.; Abuhattum, S.; Beck, T.; Müller, P.; Maharana, S.; Cojoc, G.; Girardo, S.; Hermann, A.; Alberti, S.; Guck, J.
10.1101/2020.10.30.361808 — biophysics — Posted on 2020-10-30
161 A Python-based optimization framework for high-performance genomics
Shajii, A. R.; Numanagic, I.; Leighton, A. T.; Greenyer, H.; Amarasinghe, S.; Berger, B.
10.1101/2020.10.29.361402 — bioinformatics — Posted on 2020-10-30
166 Pairwise genetic interactions modulate lipid plasma levels and cellular uptake
Zimon, M.; Huang, Y.; Trasta, A.; Liu, J. Z.; Chen, C.-Y.; Halavatyi, A.; Blattmann, P.; Klaus, B.; Whelan, C. D.; Sexton, D.; John, S.; Huber, W.; Tsai, E. A.; Pepperkok, R.; Runz, H.
10.1101/2020.10.29.360818 — genetics — Posted on 2020-10-30
168 Comparative transcriptomic analysis reveals conserved transcriptional programs underpinning organogenesis and reproduction in land plants
Julca, I.; Flores, M.; Proost, S.; Lindner, A.-C.; Hackenberg, D.; Steinbachova, L.; Michaelidis, C.; Gomes Pereira, S.; Misra, C. S.; Kawashima, T.; Borg, M.; Berger, F.; Goldberg, J.; Johnson, M.; Honys, D.; Twell, D.; Sprunck, S.; Dresselhaus, T.; Becker, J.; Mutwil, M.
10.1101/2020.10.29.361501 — evolutionary biology — Posted on 2020-10-30
170 Genome-Wide Architecture of Adaptation in Experimentally Evolved Drosophila
Barter, T. T.; Greenspan, Z. S.; Phillips, M. A.; Ranz, J. M.; Rose, M. R.; Mueller, L. D.
10.1101/2020.10.30.361857 — evolutionary biology — Posted on 2020-10-30
172 Diversification slowdown in an evolutionary cul-de-sac
Perez-Lamarque, B.; Opik, M.; Maliet, O.; Afonso Silva, A. C.; Selosse, M.-A.; Martos, F.; Morlon, H.
10.1101/2020.07.28.224790 — evolutionary biology — Posted on 2020-10-30
173 Novel enzyme for dimethyl sulfide-releasing in bacteria reveals a missing route in the marine sulfur cycle
Li, C.-Y.; Wang, X.-J.; Chen, X.-L.; Sheng, Q.; Zhang, S.; Wang, P.; Quareshy, M.; Rihtman, B.; Shao, X.; Gao, C.; Li, F.; Li, S.; Chen, Y.; Zhang, Y.-Z.
10.1101/2020.10.29.360743 — ecology — Posted on 2020-10-30
175 Minding The Gap: Range Size And Economic Use Drive Functional Trait Data Shortfall In The Atlantic Forest
Petisco-Souza, A. C.; Brum, F. T.; Marcilio-Silva, V.; Zwiener, V. P.; Zanella, A.; Dias, A. S.; Gonzalez-Melo, A.; Jansen, S.; Mazzochini, G. G.; Niinemets, U.; Pillar, V. D.; Sosinski, E.; Marques, M. C. M.; Carlucci, M. B.
10.1101/2020.10.30.361311 — ecology — Posted on 2020-10-30
178 Transient systemic inflammation in adult male mice results in underweight progeny
Rokade, S. T.; Upadhya, M.; Bhat, D. S.; Subhedar, N.; Yajnik, C. S.; Ghose, A.; Rath, S.; Bal, V.
10.1101/2020.10.30.358697 — immunology — Posted on 2020-10-30
185 The H2A.J histone variant contributes to Interferon-Stimulated Gene expression in senescence by its weak interaction with H1 and the derepression of repeated DNA sequences
Mangelinck, A.; Coudereau, C.; Courbeyrette, R.; Ouararhni, K.; Hamiche, A.; Redon, C. E.; Bonner, W. M.; Van Dijk, E.; Derbois, C.; Olaso, R.; Deleuze, J.-F.; Fenaille, F.; Ruebe, C. E.; Thuret, J.-Y.; MANN, C.
10.1101/2020.10.29.361204 — genetics — Posted on 2020-10-30
188 GDV1 C-terminal truncation of 39 amino acids disrupts sexual commitment in Plasmodium falciparum
Tiburcio, M.; Hitz, E.; Niederwieser, I.; Kelly, G.; Davies, H.; Doerig, C.; Billker, O.; Voss, T. S.; Treeck, M.
10.1101/2020.10.28.360123 — microbiology — Posted on 2020-10-30
189 Structure-based functional study of a peptide of an ecdysozoan superfamily: reveling a common molecular architecture and receptor-interacting residues
Chen, Y.-R.; Hsiao, N.-W.; Huang, S.-S.; Chang, C.-C.; Lee, Y.-Z.; Tsai, J.-R.; Lin, H.-C.; Toullec, J.-Y.; Lee, C.-Y.; Lyu, P.-C.
10.1101/2020.10.29.360867 — biochemistry — Posted on 2020-10-30
192 Visualization of Phase-Amplitude Coupling Using Rhythmic High-Frequency Activity
Hashimoto, H.; Khoo, H. M.; Yanagisawa, T.; Tani, N.; Oshino, S.; Kishima, H.; Hirata, M.
10.1101/2020.08.12.247775 — neuroscience — Posted on 2020-10-29
193 Metabolic flux signatures of the ER unfolded protein response in vivo reveal decreased hepatic de novo lipogenesis and mobilization of lipids from adipose tissue to liver
Schneider, C. P.; Peng, L.; Yuen, S.; Chang, M.; Karapetyan, R.; Nyangau, E.; Mohammed, H.; Palacios, H.; Ziari, N.; Joe, L. K.; Frakes, A.; Dillin, A.; Hellerstein, M. K.
10.1101/2020.10.29.360073 — physiology — Posted on 2020-10-29
196 New Genes in Drosophila Quickly Evolved Essential Functions in Viability During Development
Xia, S.; VanKuren, N. W.; Chen, C.; Zhang, L.; Kemkemer, C.; Shao, Y.; Jia, H.; Lee, U.; Advani, A. S.; Gschwend, A.; Vibranovski, M.; Chen, S.; Zhang, Y. E.; Long, M.
10.1101/2020.10.27.357848 — evolutionary biology — Posted on 2020-10-29
199 LncRNA PAINT is Associated with Aggressive Prostate Cancer and Dysregulation of Slug and Related Genes
Hasan, M. F.; Ganapathy, K.; Sun, J.; Khatib, A.; Andl, T.; Soulakova, J. N.; Coppola, D.; Zhang, W. i.; Chakrabarti, R.
10.1101/2020.10.29.361105 — cancer biology — Posted on 2020-10-29
201 Unique Evolution of Antiviral Tetherin in Bats
Hayward, J. A.; Tachedjian, M.; Johnson, A.; Irving, A. T.; Gordon, T. B.; Cui, J.; Nicolas, A.; Smith, I.; Boyd, V.; Marsh, G. A.; Baker, M. L.; Wang, L.-F.; Tachedjian, G.
10.1101/2020.04.08.031203 — evolutionary biology — Posted on 2020-10-29
202 Proliferation impairs cell viability via energy depletion
Galichon, P.; Lannoy, M.; Li, L.; Vandermeersch, S.; Legouis, D.; Valerius, M. T.; Hadchouel, J.; Bonventre, J. V.
10.1101/2020.04.24.054643 — cell biology — Posted on 2020-10-29
205 A configurable model of the synaptic proteome reveals the molecular mechanisms of disease co-morbidity.
Sorokina, O.; McLean, C.; Croning, M. D.; Heil, K. F.; Wysocka, E.; He, X.; Sterratt, D. C.; Grant, S.; Simpson, T. I.; Armstrong, J. D.
10.1101/2020.10.27.356899 — systems biology — Posted on 2020-10-29
211 A centrifuge-based method for identifying novel genetic traits that affect root-substrate adhesion in Arabidopsis thaliana
Eldridge, B. M.; Larson, E. R.; Weldon, L.; Smyth, K. M.; Sellin, A. N.; Chenchiah, I. V.; Liverpool, T. B.; Grierson, C. S.
10.1101/2020.05.14.095448 — plant biology — Posted on 2020-10-29
212 Sodium channel toxin-resistance mutations do not govern batrachotoxin (BTX) autoresistance in poison birds and frogs
Abederemane-Ali, F.; Rossen, N. D.; Kobiela, M. E.; Craig, R. A.; Garrison, C. E.; O'Connell, L. A.; Du Bois, J.; Dumbacher, J. P.; Minor, D. L.
10.1101/2020.10.29.361212 — biophysics — Posted on 2020-10-29
213 Real-Time Multi-Angle Projection Imaging of Biological Dynamics
Chang, B.-J.; Sapoznik, E.; Pohlkamp, T.; Terrones, T.; Welf, E. S.; Manton, J. D.; Roudot, P.; Hake, K.; Whitehead, L.; York, A. G.; Dean, K. M.; Fiolka, R. P.
10.1101/2020.10.29.355917 — biophysics — Posted on 2020-10-29
215 A novel family of secreted proteins linked to plant gall development
Korgaonkar, A.; Han, C.; Lemire, A. L.; Siwanowicz, I.; Bennouna, D.; Kopec, R.; Andolfatto, P.; Shigenobu, S.; Stern, D. L.
10.1101/2020.10.28.359562 — genetics — Posted on 2020-10-29
216 Cell size is a determinant of stem cell potential during aging
Lengefeld, J.; Cheng, C.-W.; Maretich, P.; McReynolds, M. R.; Blair, M.; Hagen, H.; Sullivan, E. J.; Majors, K.; Roberts, C.; Kang, J. H.; Steiner, J.; Miettinen, T. P.; Manalis, S.; Antebi, A.; Morrison, S. J.; Lees, J.; Boyer, L.; Yilmaz, O. H.; Amon, A.
10.1101/2020.10.27.355388 — cell biology — Posted on 2020-10-29
222 Global population structure and genotyping framework for genomic surveillance of the major dysentery pathogen, Shigella sonnei
Hawkey, J.; Paranagama, K.; Baker, K. S.; Bengtsson, R. J.; Weill, F.-X.; Thomson, N. R.; Baker, S.; Cerdeira, L.; Iqbal, Z.; Hunt, M.; Ingle, D. J.; Dallman, T. J.; Jenkins, C.; Williamson, D. A.; Holt, K. E.
10.1101/2020.10.29.360040 — microbiology — Posted on 2020-10-29
227 Sclerostin directly stimulates osteocyte synthesis of fibroblast growth factor-23
Ito, N.; Prideaux, M.; Wijenayaka, A. R.; Yang, D.; Ormsby, R. T.; Bonewald, L. F.; Atkins, G. J.
10.1101/2020.10.29.360024 — physiology — Posted on 2020-10-29
228 Transcriptomic profiling of fibropapillomatosis in green sea turtles (Chelonia mydas) from South Texas
Blackburn, N. B.; Leandro, A. C.; Nahvi, N.; Devlin, M. A.; Leandro, M.; Martinez Escobedo, I.; Peralta, J. M.; George, J.; Stacy, B. A.; deMaar, T. W.; Blangero, J.; Keniry, M.; Curran, J. E.
10.1101/2020.10.29.360834 — cancer biology — Posted on 2020-10-29
229 A Mechanistic Basis for Inhibition of TREK-2 K2P Channels by Norfluoxetine
Proks, P.; Schewe, M.; Conrad, L. J.; Rao, S.; Rathje, K.; Rodstrom, K. E.; Carpenter, E. P.; Baukrowitz, T.; Tucker, S. J.
10.1101/2020.10.29.360966 — biophysics — Posted on 2020-10-29
232 Molecular and evolutionary mechanisms of yeast thermotolerance
Abrams, M. B.; Dubin, C. A.; AlZaben, F.; Bravo, J.; Joubert, P. M.; Weiss, C. V.; Brem, R. B.
10.1101/2020.08.31.275453 — evolutionary biology — Posted on 2020-10-29
234 Sexual selection theory meets disease vector control: Testing harmonic convergence as a "good genes" signal in Aedes aegypti mosquitoes
League, G. P.; Harrington, L. C.; Pitcher, S. A.; Geyer, J. K.; Baxter, L. L.; Montijo, J.; Rowland, J. G.; Johnson, L. M.; Murdock, C. C.; Cator, L. J.
10.1101/2020.10.29.360651 — ecology — Posted on 2020-10-29
236 Prednisolone rescues Duchenne Muscular Dystrophy phenotypes in human pluripotent stem cells-derived skeletal muscle in vitro
Al Tanoury, Z.; Zimmermann, J. F.; Rao, J.; Siero, D.; McNamara, H.; Cherrier, T.; Hick, A.; Bousson, F.; Fugier, C.; Marchiano, F.; Habermann, B.; Chal, J.; Nesmith, A. P.; Gapon, S.; Wagner, E.; Bassel-Duby, R.; Olson, E.; Cohen, A. E.; Parker, K. K.; Pourquie, O.
10.1101/2020.10.29.360826 — cell biology — Posted on 2020-10-29
237 Rab34 GTPase mediates ciliary membrane biogenesis in the intracellular ciliogenesis pathway
Ganga, A. K.; Kennedy, M. C.; Oguchi, M. E.; Gray, S. D.; Oliver, K. E.; Knight, T. A.; De La Cruz, E. M.; Homma, Y.; Fukuda, M.; Breslow, D. K.
10.1101/2020.10.29.360891 — cell biology — Posted on 2020-10-29
238 A Library Of Induced Pluripotent Stem Cells From Clinically Well-Characterized, Diverse Healthy Human Individuals
Schaniel, C.; Dhanan, P.; Hu, B.; Xiong, Y.; Raghunandan, T.; Gonzalez, D. M.; D'Souza, S. L.; Yadaw, A.; Hansen, J.; Jayaraman, G.; Mathew, B.; Machado, M.; Berger, S.; Tripodi, J.; Najfeld, V.; Garg, J.; Miller, M.; Lynch, C.; Michelis, K.; Tangirala, N.; Weerahandi, H.; Thomas, D. C.; Sebra, R.; Mahajan, M.; Schadt, E.; Vidovic, D.; Schuerer, S. C.; Goldfarb, J.; Azeloglu, E. U.; Birtwistle, M. R.; Sobie, E. A.; Kovacic, J. C.; Dubois, N. C.; Iyengar, R.
10.1101/2020.10.29.360909 — cell biology — Posted on 2020-10-29
239 Repulsive electrostatic interactions modulate dense and dilute phase properties of biomolecular condensates
Crabtree, M. D.; Holland, J.; Kompella, P. S.; Babl, L.; Turner, N. N.; Baldwin, A. J.; Nott, T. J.
10.1101/2020.10.29.357863 — cell biology — Posted on 2020-10-29
240 Chromatin-associated protein complexes link DNA base J and transcription termination in Leishmania
Jensen, B. C.; Phan, I. Q.; McDonald, J. R.; Sur, A.; Gillespie, M. A.; Ranish, J. A.; Parsons, M.; Myler, P. J.
10.1101/2020.05.26.117721 — molecular biology — Posted on 2020-10-29
241 COVID-19 cytokines and the hyperactive immune response: Synergism of TNF-α and IFN-γ in triggering inflammation, tissue damage, and death
Karki, R.; Sharma, B. R.; Tuladhar, S.; Williams, E. P.; Zalduondo, L.; Samir, P.; Zheng, M.; Sundaram, B.; Banoth, B.; Malireddi, R. K. S.; Schreiner, P.; Neale, G.; Vogel, P.; Webby, R.; Jonsson, C. B.; Kanneganti, T.-D.
10.1101/2020.10.29.361048 — immunology — Posted on 2020-10-29
242 Distinct cellular immune profiles in the airways and blood of critically ill patients with COVID 19
Saris, A.; Reijnders, T. D.; Nossent, E. J.; Schuurman, A. R.; Verhoeff, J.; van Asten, S. D.; Bontkes, H. J.; Blok, S. G.; Duitman, J.; Bogaard, H. J.; Heunks, L.; Lutter, R.; van der Poll, T.; Garcia Vallejo, J. J.
10.1101/2020.10.29.360586 — immunology — Posted on 2020-10-29
244 Epitope profiling reveals binding signatures of SARS-CoV-2 immune response and cross-reactivity with endemic HCoVs
Stoddard, C. I.; Galloway, J.; Chu, H. Y.; Shipley, M. M.; Itell, H. L.; Wolf, C. R.; Logue, J. K.; Magedson, A.; Sung, K.; Garrett, M.; Crawford, K. H.; Laserson, U.; Matsen, F. A.; Overbaugh, J.
10.1101/2020.10.29.360800 — immunology — Posted on 2020-10-29
247 Protein kinase CK2 alpha prime and alpha-synuclein constitute a key regulatory pathway in Huntington's disease
Yu, D.; Zarate, N.; Cuccu, F.; Yue, J. S.; Brown, T. G.; Tsai, W.; Mansky, R.; Jiang, K.; Kim, H.; Nanclares, C.; Nichols-Meade, T.; Larson, S. N.; Gundry, K.; Zhang, Y.; Benneyworth, M.; Öz, G.; Cvetanovic, M.; Araque, A.; Gomez-Pastor, R.
10.1101/2020.10.29.359380 — neuroscience — Posted on 2020-10-29
249 Beam image-shift accelerated data acquisition for near-atomic resolution single-particle cryo-electron tomography
Bouvette, J.; Liu, H.-F.; Du, X.; Zhou, Y.; Sikkema, A. P.; Rezende E Mello, J. D. F.; Klemm, B.; Huang, R.; Schaaper, R. M.; Borgnia, M. J.; Bartesaghi, A.
10.1101/2020.09.24.294983 — biochemistry — Posted on 2020-10-29
250 Evolution and adaptation of Pseudomonas aeruginosa in the paranasal sinuses of people with cystic fibrosis
Armbruster, C. R.; Marshall, C. W.; Melvin, J. A.; Zemke, A. C.; Garber, A. I.; Moore, J.; Li, K.; Zamora, P. F.; Fritz, I. L.; Manko, C. D.; Weaver, M. L.; Gaston, J.; Morris, A.; Methe, B.; Lee, S. E.; Cooper, V. S.; Bomberger, J. M.
10.1101/2020.10.29.359844 — microbiology — Posted on 2020-10-29
251 Predicting COVID-19 Severity with a Specific Nucleocapsid Antibody plus Disease Risk Factor Score
Sen, S.; Sanders, E. C.; Gabriel, K. N.; Miller, B. M.; Isoda, H. M.; Salcedo, G. S.; Garrido, J. E.; Dyer, R. P.; Nakajima, R.; Jain, A.; Santos, A. M.; Bhuvan, K.; Tifrea, D. F.; Ricks-Oddie, J. L.; Felgner, P. L.; Edwards, R. A.; Majumdar, S.; Weiss, G. A.
10.1101/2020.10.15.341743 — immunology — Posted on 2020-10-29
252 The adaptive benefit of increases in hemoglobin-O2 affinity is contingent on tissue O2 diffusing capacity in high-altitude deer mice
Wearing, O. H.; Ivy, C. M.; Guttierrez-Pinto, N.; Velotta, J. P.; Campbell-Staton, S. C.; Natarajan, C.; Cheviron, Z. A.; Storz, J. F.; Scott, G. R.
10.1101/2020.10.29.357665 — physiology — Posted on 2020-10-29
254 An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen
Morley, V. J.; Kinnear, C. L.; Sim, D. G.; Olson, S. N.; Jackson, L. M.; Hansen, E.; Usher, G. A.; Showalter, S. A.; Pai, M. P.; Woods, R. J.; Read, A. F.
10.1101/2020.04.24.059444 — evolutionary biology — Posted on 2020-10-29
255 G3BP1 tethers the TSC complex to lysosomes and suppresses mTORC1 in the absence of stress granules
Prentzell, M. T.; Rehbein, U.; Cadena Sandoval, M.; De Meulemeester, A.-S.; Baumeister, R.; Brohee, L.; Berdel, B.; Bockwoldt, M.; Carroll, B.; von Deimling, A.; Demetriades, C.; Figlia, G.; Heberle, A. M.; Heiland, I.; Holzwarth, B.; Huber, L. A.; Jaworski, J.; Kern, K.; Kopach, A.; Korolchuk, V. I.; van 't Land-Kuper, I.; Macias, M.; Nellist, M.; Pusch, S.; Reil, M.; Reintjes, A.; Reuter, F.; Scheldeman, C.; Stefan, E.; Teleman, A.; Torres-Quesada, O.; Trump, S.; de Witte, P.; Yordanov, T.; Opitz, C. A.; Thedieck, K.
10.1101/2020.04.16.044081 — cell biology — Posted on 2020-10-29
256 Reconstruction of natural images from responses of primate retinal ganglion cells
Brackbill, N.; Rhoades, C.; Kling, A.; Shah, N. P.; Sher, A.; Litke, A. M.; Chichilnisky, E. J.
10.1101/2020.05.04.077693 — neuroscience — Posted on 2020-10-29
258 Sex-biased ZRSR2 mutations in myeloid malignancies impair plasmacytoid dendritic cell activation and apoptosis
Togami, K.; Chung, S. S.; Madan, V.; Cabal-Hierro, L.; Taylor, J.; Kim, S. S.; Griffin, G. K.; Ghandi, M.; Li, J.; Li, Y. Y.; Angelot-Delettre, F.; Biichle, S.; Seiler, M.; Buonamici, S.; Lovitch, S. B.; Louissaint, A.; Morgan, E. A.; Jardin, F.; Piccaluga, P. P.; Weinstock, D. M.; Hammerman, P. S.; Yang, H.; Konopleva, M.; Pemmaraju, N.; Garnache-Ottou, F.; Abdel-Wahab, O.; Koeffler, H. P.; Lane, A. A.
10.1101/2020.10.29.360503 — cancer biology — Posted on 2020-10-29
260 Large-scale single-cell analysis reveals critical immune characteristics of COVID-19 patients
Ren, X.; Wen, W.; Fan, X.; Hou, W.; Su, B.; Cai, P.; Li, J.; Liu, Y.; Tang, F.; Zhang, F.; Yang, Y.; He, J.; Ma, W.; He, J.; Wang, P.; Cao, Q.; Chen, F.; Chen, Y.; Cheng, X.; Deng, G.; Deng, X.; Ding, W.; Feng, Y.; Gan, R.; Guo, C.; Guo, W.; He, S.; Jiang, C.; Liang, J.; Li, Y.-M.; Lin, J.; Ling, Y.; Liu, H.; Liu, J.; Liu, N.; Liu, Y.; Luo, M.; Ma, Q.; Song, Q.; Sun, W.; Wang, G.; Wang, F.; Wang, Y.; Wen, X.; Wu, Q.; Xu, G.; Xie, X.; Xiong, X.; Xing, X.; Xu, H.; Yin, C.; Yu, D.; Yu, K.; Yuan, J.; Zhang, B.; Zhang, T.; Zhao, J.; Zhao, P.; Zhou, J.; Zhou, W.; Zhong, S.; Zhong, X.; Zhang, S.; Zhu
10.1101/2020.10.29.360479 — genomics — Posted on 2020-10-29
261 Genomic and microscopic evidence of stable high density and maternally inherited Wolbachia infections in Anopheles mosquitoes
Walker, T.; Quek, S.; Jeffries, C. L.; Bandibabone, J.; Dhokiya, V.; Bamou, R.; Kristan, M.; Messenger, L. A.; Gidley, A.; Hornett, E. A.; Anderson, E. R.; Cansado-Utrilla, C.; Hegde, S.; Bantuzeko, C.; Stevenson, J. C.; Lobo, N. F.; Wagstaff, S.; Nkondjio, C. A.; Heinz, E.; Hughes, G.
10.1101/2020.10.29.357400 — microbiology — Posted on 2020-10-29
262 A Novel Surgical Method for Continuous Intra-Portal Infusion of Gut Microbial Metabolites in Mice
Orabi, D.; Osborn, L. J.; Fung, K.; Aucejo, F.; Choucair, I.; DeLucia, B.; Wang, Z.; Claesen, J.; Brown, J. M.
10.1101/2020.10.29.360628 — microbiology — Posted on 2020-10-29
263 Novel SARS-CoV-2 Whole-genome sequencing technique using Reverse Complement PCR enables fast and accurate outbreak analysis
Wolters, F.; Coolen, J. P. M.; Tostmann, A.; van Groningen, L. F. J.; Bleeker-Rovers, C. P.; Tan, E. C. T. H.; van der Geest-Blankert, N.; Hautvast, J. L. A.; Hopman, J.; Wertheim, H. F. L.; Rahamat-Langendoen, J. C.; Storch, M.; Melchers, W. J. G.
10.1101/2020.10.29.360578 — microbiology — Posted on 2020-10-29
264 Protective Effects of STI-2020 Antibody Delivered Post-Infection by the Intranasal or Intravenous Route in a Syrian Golden Hamster COVID-19 Model
Fu, Y.; Maruyama, J.; Singh, A.; Lim, R.; Ledesma, A.; Lee, D.; Rivero-Nava, L.; Ko, J.; Rivera, I.; Sattler, R. A.; Manning, J. T.; Kerwin, L.; Zhou, H.; Brunswick, M.; Bresson, D.; Ji, H.; Paessler, S.; Allen, R. D.
10.1101/2020.10.28.359836 — microbiology — Posted on 2020-10-29
265 Global Absence and Targeting of Protective Immune States in Severe COVID-19.
Combes, A. J.; Courau, T.; Kuhn, N. F.; Hu, K. H.; Ray, A.; Chen, W. S.; Clearly, S. J.; Chew, N. W.; Kushnoor, D.; Reeder, G. C.; Shen, A.; Tsui, J.; Hiam-Galvez, K. J.; Munoz-Sandoval, P.; Zhu, W. S.; Lee, D. S.; Sun, Y.; You, R.; Magnen, M.; Rodriguez, L.; Leligdowicz, A.; Zamecnik, C. R.; Loudermilk, R. P.; Wilson, M. R.; Ye, C. J.; Fragiadakis, G. K.; Looney, M. R.; Chan, V.; Ward, A.; Carrillo, S.; Matthay, M.; Erle, D. J.; Woodruff, P. G.; Langelier, C.; Kangelaris, K.; Hendrickson, C. M.; Calfee, C.; Rao, A. A.; Krummel, M. F.
10.1101/2020.10.28.359935 — immunology — Posted on 2020-10-29
267 KCC2 is required for the survival of mature neurons but not for their development
Kontou, G.; Ng, J.; Cardarelli, R. A.; Howden, J.; Choi, C.; Ren, Q.; Kittler, J.; Brandon, N.; Moss, S. J.; Smalley, J. L.
10.1101/2020.10.29.360875 — neuroscience — Posted on 2020-10-29
273 Transcriptional response to host chemical cues underpins expansion of host range in a fungal plant pathogen lineage
Kusch, S.; Larrouy, J.; Ibrahim, H. M. M.; Gasset, N.; Navaud, O.; Mbengue, M.; Zanchetta, C.; Roques, C.; Donnadieu, C.; Raffaele, S.
10.1101/2020.10.29.360412 — genomics — Posted on 2020-10-29
274 Role of an atypical cadherin gene, Cdh23 in prepulse inhibition and its implication in schizophrenia
Balan, S.; Ohnishi, T.; Watanabe, A.; Ohba, H.; Iwayama, Y.; Toyoshima, M.; Hara, T.; Hisano, Y.; Miyasaka, Y.; Toyota, T.; Shimamoto-Mitsuyama, C.; Maekawa, M.; Numata, S.; Ohmori, T.; Shimogori, T.; Dean, B.; Kikkawa, Y.; Hayashi, T.; Yoshikawa, T.
10.1101/2020.10.29.360180 — genetics — Posted on 2020-10-29
276 Regulation of intracellular signaling and neuron function by Bardet-Biedl Syndrome proteins in patient-specific iPSC-derived neurons
Wang, L.; Liu, Y.; Stratigopoulos, G.; Panigrahi, S.; Sui, L.; Leduc, C. A.; Glover, H. J.; De Rosa, M. C.; Burnett, L. C.; Williams, D. J.; Shang, L.; Goland, R.; Tsang, S. H.; Wardlaw, S.; Egli, D.; Zheng, D.; Doege, C. A.; Leibel, R. L.
10.1101/2020.10.29.359851 — cell biology — Posted on 2020-10-29
277 FANCM regulates repair pathway choice at stalled replication forks
Panday, A.; Willis, N. A.; Elango, R.; Menghi, F.; Duffey, E. E.; Liu, E. T.; Scully, R.
10.1101/2020.10.29.357996 — molecular biology — Posted on 2020-10-29
280 Neuroimaging: Into the Multiverse
Dafflon, J.; F. Da Costa, P.; Vasa, F.; Pio Monti, R.; Bzdok, D.; Hellyer, P. J.; Turkheimer, F.; Smallwood, J.; Jones, E.; Leech, R.
10.1101/2020.10.29.359778 — neuroscience — Posted on 2020-10-29
282 Optogenetic interrogation of the role of striatal patches in habit formation and inhibition of striatal dopamine
Nadel, J. A.; Pawelko, S. S.; Scott, J. R.; McLaughlin, R.; Fox, M.; Hollon, N. G.; Howard, C. D.
10.1101/2020.10.29.359265 — neuroscience — Posted on 2020-10-29
284 Infant functional connectivity fingerprints predict long-term language and pre-literacy outcomes
Yu, X.; Ferradal, S.; Sliva, D. D.; Dunstan, J.; Carruthers, C.; Sanfilippo, J.; Zuk, J.; Zollei, L.; Boyd, E.; Gagoski, B.; Grant, E. P.; Gaab, N.
10.1101/2020.10.29.360081 — neuroscience — Posted on 2020-10-29
286 Low nitrogen availability inhibits the phosphorus starvation response in maize (Zea mays ssp. mays L.)
Torres-Rodriguez, J. V.; Salazar-Vidal, M. N.; Chavez Montes, R. A.; Massange-Sanchez, J. A.; Gillmor, C. S.; Sawers, R. J. H.
10.1101/2020.10.29.360487 — plant biology — Posted on 2020-10-29
288 The evolution of hematopoietic cells under cancer therapy
Pich, O.; Cortes-Bullich, A.; Muinos, F.; Pratcorona, M.; Gonzalez-Perez, A.; Lopez-Bigas, N.
10.1101/2020.10.29.360230 — cancer biology — Posted on 2020-10-29
290 ViMIC: A Database of Human Disease-related Virus Mutations, Integration Sites and Cis-effects
Wang, Y.; Tong, Y.; Zhang, Z.; Zheng, R.; Huang, D.; Yang, J.; Zong, H.; Tan, F.; Zhang, X.
10.1101/2020.10.28.359919 — bioinformatics — Posted on 2020-10-29
295 Genetic ancestry predicts male-female affiliation in a natural baboon hybrid zone
Fogel, A. S.; McLean, E. M.; Gordon, J. B.; Archie, E. A.; Tung, J.; Alberts, S. C.
10.1101/2020.10.28.358002 — evolutionary biology — Posted on 2020-10-29
296 Chromatin dynamics associated with sexual differentiation in a UV sex determination system
Gueno, J.; Bourdereau, S.; Cossard, G.; Godfroy, O.; Lipinska, A. P.; Tirichine, L.; Cock, J. M.; Coelho, S. M.
10.1101/2020.10.29.359190 — evolutionary biology — Posted on 2020-10-29
297 Morphological and biochemical responses of Sphagnum mosses to environmental changes
Sytiuk, A.; Cereghino, R.; Hamard, S.; Delarue, F.; Dorrepaal, E.; Kuttim, M.; Lamentowicz, M.; Pourrut, B.; Robroek, B.; Tuittila, E.-S.; Jassey, V.
10.1101/2020.10.29.360388 — ecology — Posted on 2020-10-29
299 Genomic surveillance and improved molecular typing of Bordetella pertussis using wgMLST
Weigand, M. R.; Peng, Y.; Pouseele, H.; Kania, D.; Bowden, K. E.; Williams, M. M.; Tondella, M. L.
10.1101/2020.10.28.360149 — microbiology — Posted on 2020-10-29
301 Ser/Thr kinase-dependent phosphorylation of the peptidoglycan hydrolase CwlA controls its export and modulates cell division in Clostridioides difficile
Garcia-Garcia, T.; Poncet, S.; Cuenot, E.; Douche, T.; Giai Gianetto, Q.; PELTIER, J.; Courtin, P.; Chapot-Chartier, M.-P.; Matondo, M.; Dupuy, B.; Candela, T.; Martin-Verstraete, I.
10.1101/2020.10.29.360313 — microbiology — Posted on 2020-10-29
302 Perceptual Degradation Affects Stop-Signal Performance in Normal Healthy Adults
Soloveva, M. V.; Jamadar, S. D.; Hughes, M.; Velakoulis, D.; Poudel, G. R.; Georgiou-Karistianis, N.
10.1101/2020.10.29.351502 — neuroscience — Posted on 2020-10-29
303 Synthesis and preclinical evaluation of MTP38 as a novel PET ligand for phophodiesterase 7 in the brain
Obokata, N.; Seki, C.; Hirata, T.; Maeda, J.; Ishii, H.; Nagai, Y.; Matsumura, T.; Takakuwa, M.; Fukuda, H.; Minamimoto, T.; Kawamura, K.; Zhang, M.-R.; Nakajima, T.; Saijo, T.; Higuchi, M.
10.1101/2020.10.29.354696 — neuroscience — Posted on 2020-10-29
305 crispr2vec: Machine Learning Model Predicts Off-Target Cuts of CRISPR systems
Tara Basu Trivedi, T.; Boger, R.; Govinda Kamath, G.; Evangelopoulos, G.; Cate, J.; Doudna, J.; Hidary, J.
10.1101/2020.10.28.359885 — synthetic biology — Posted on 2020-10-29
308 Cytidine triphosphate synthase two provides nucleotides for chloroplast development and stress responses
Alamdari, K.; Fisher, K. E.; Welsh, D. W.; Rai, S.; Palos, K.; Nelson, A. D.; Woodson, J. D.
10.1101/2020.10.28.360057 — plant biology — Posted on 2020-10-29
309 Aberrant Ca2+ homeostasis in adipocytes links inflammation to metabolic dysregulation in obesity
Guney, E.; Arruda, A. P.; Parlakgul, G.; Cagampan, E.; Min, N.; Lee, Y.; Greene, L.; Tsaousidou, E.; Inouye, K.; Han, M. S.; Davis, R. J.; Hotamisligil, G. S.
10.1101/2020.10.28.360008 — physiology — Posted on 2020-10-29
311 Vertical-junction Photodiodes for High-resolution Retinal Prostheses
Huang, T. W.; Kamins, T. I.; Chen, Z. C.; Wang, B.-Y.; Bhuckory, M. B.; Galambos, L.; Ho, E.; Ling, T.; Afshar, S.; Shin, A.; Zuckerman, V.; Harris, J. S.; Mathieson, K.; Palanker, D.
10.1101/2020.10.28.353128 — bioengineering — Posted on 2020-10-29
312 Structural basis for a natural circular permutation in proteins
Nonis, S. G.; Haywood, J.; Schmidberger, J. W.; Bond, C. S.; Mylne, J. S.
10.1101/2020.10.28.360099 — biochemistry — Posted on 2020-10-29
313 GWAS in Africans identifies novel lipids loci and demonstrates heterogenous association within Africa
Bentley, A. R.; Chen, G.; Doumatey, A. P.; Shriner, D.; Meeks, K.; Gouveia, M. H.; Ekoru, K.; Zhou, J.; Africa America Diabetes Mellitus Collaborators, ; Adeyemo, A.; Rotimi, C. N.
10.1101/2020.10.28.359497 — genomics — Posted on 2020-10-29
318 Oleic acid triggers hippocampal neurogenesis by binding to TLX/NR2E1
Kandel, P.; Semerci, F.; Bajic, A.; Baluya, D.; Ma, L.; Chen, K.; Cao, A.; Phongmekhin, T.; Matinyan, N.; Choi, W.; Jimenez-Panizo, A.; Chamakuri, S.; Raji, I. O.; Chang, L.; MacKenzie, K. R.; Fuentes-Prior, P.; Estebanez-Perpina, E.; Benn, C. L.; Moore, D. D.; Venken, K.; Young, D. W.; Maletic-Savatic, M.
10.1101/2020.10.28.359810 — neuroscience — Posted on 2020-10-29
319 Neural basis of opioid-induced respiratory depression and its rescue
Liu, S.; Kim, D.-I.; Oh, T. G.; Pao, G. M.; Kim, J. H.; Palmiter, R. D.; Banghart, M. M.; Lee, K.-F.; Evans, R. M.; Han, S.
10.1101/2020.10.28.359893 — neuroscience — Posted on 2020-10-29
320 HEXOKINASE1 interferes with cytokinin synthesis and strigolactone perception during sugar-induced shoot branching
Barbier, F. F.; Cao, D.; Fichtner, F.; Weiste, C.; Perez-Garcia, M.-D.; Caradeuc, M.; Le Gourrierec, J.; Sakr, S.; Beveridge, C. A.
10.1101/2020.10.28.359927 — plant biology — Posted on 2020-10-29
323 The propofol binding sites of prokaryotic voltage-gated sodium channels
Yang, E. C.; Bu, W.; Suma, A.; Carnevale, V.; Grasty, K.; Loll, P.; Woll, K.; Bhanu, N.; Garcia, B. A.; Eckenhoff, R. G.; Covarrubias, M.
10.1101/2020.10.28.359513 — biophysics — Posted on 2020-10-29
324 Absolute measurement of cellular activities using photochromic single-fluorophore biosensors
Gielen, V.; Mönkemöller, V.; Shen, Y.; Hofkens, J.; Vanden Berghe, P.; Campbell, R. E.; Moeyaert, B.; Dedecker, P.
10.1101/2020.10.29.360214 — biophysics — Posted on 2020-10-29
325 Heat hypersensitivity of ryanodine receptor type 1 mutants implicated in malignant hyperthermia
Oyama, K.; Zeeb, V.; Yamazawa, T.; Murayama, T.; Oyamada, H.; Harada, Y.; Fukuda, N.; Ishiwata, S.; Suzuki, M.
10.1101/2020.10.29.351452 — biophysics — Posted on 2020-10-29
328 Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva
Williams, E.; Bagarova, J.; Kerr, G.; Xia, D.-D.; Place, E. S.; Dey, D.; Shen, Y.; Bocobo, G. A.; Mohedas, A. H.; Huang, X.; Sanderson, P. E.; Lee, A.; Zheng, W.; Economides, A. N.; Smith, J. C.; Yu, P. B.; Bullock, A. N.
10.1101/2020.10.29.360370 — molecular biology — Posted on 2020-10-29
329 Numerical Instabilities in Analytical Pipelines Lead to Large and Meaningful Variability in Brain Networks
Kiar, G.; Chatelain, Y.; de Oliveira Castro, P.; Petit, E.; Rokem, A.; Varoquaux, G.; Misic, B.; Evans, A. C.; Glatard, T.
10.1101/2020.10.15.341495 — neuroscience — Posted on 2020-10-29
330 Split-HaloTag(R) Imaging Assay for Sophisticated Microscopy of Protein-Protein Interactions in planta
Minner-Meinen, R.; Weber, J. N.; Albrecht, A.; Matis, R.; Behnecke, M.; Tietge, C.; Frank, S.; Schulze, J.; Buschmann, H.; Walla, P. J.; Mendel, R. R.; Haensch, R.; Kaufholdt, D.
10.1101/2020.06.08.139378 — plant biology — Posted on 2020-10-29
331 Pulmonary acini exhibit complex changes during postnatal rat lung development
Haberthür, D.; Yao, E.; Barre, S. F.; Cremona, T. P.; Tschanz, S. A.; Schittny, J. C.
10.1101/786681 — physiology — Posted on 2020-10-29
332 IFN-{lambda}4 may contribute to HCV persistence by increasing ER stress and enhancing IRF1 signaling
Onabajo, O. O.; Wang, F.; Lee, M.-H.; Florez-Vargas, O.; Obajemu, A.; Castro, M. A. A.; Tanikawa, C.; Vargas, J.; Liao, S.-F.; Song, C.; Huang, Y.-H.; Shen, C.-Y.; Banday, A. R.; O'Brien, T. R.; Hu, Z.; Matsuda, K.; Robertson, A. G.; Prokunina-Olsson, L.
10.1101/2020.10.28.359398 — cancer biology — Posted on 2020-10-29
335 Asymmetric robustness in the feedback control of the retinoic acid network response to environmental disturbances
Parihar, M.; Bendelac-Kapon, L.; Gur, M.; Belorkar, A.; Achanta, S.; Kinberg, K.; Vadigepalli, R.; Fainsod, A.
10.1101/2020.07.15.203794 — developmental biology — Posted on 2020-10-29
337 Endothelial iron homeostasis regulates BBB integrity via the HIF2α-Ve-cadherin pathway
Rand, D.; Ravid, O.; Atrakchi, D.; Israelov, H.; Bresler, Y.; Shemesh, C.; Omesi, L.; Liraz-Zaltsman, S.; Gosselet, F.; Maskrey, T.; Schnaider Beeri, M.; Wipf, P.; Cooper, I.
10.1101/2020.10.28.358473 — neuroscience — Posted on 2020-10-29
338 Characterisation of the biosurfactants from phyllosphere colonising Pseudomonads and their effect on plant colonisation and diesel degradation
Oso, S.; Fuchs, F. L.; Daunaraviciute, S.; Übermuth, C.; Zander, L.; Remus, D. M.; Stötzel, I.; Wüst, M.; Schreiber, L.; Remus-Emsermann, M. N.
10.1101/2020.10.27.358416 — microbiology — Posted on 2020-10-29
342 Innervation and Neuronal Control of the Mammalian Sinoatrial Node: A Comprehensive Atlas
Hanna, P.; Dacey, M. J.; Brennan, J.; Moss, A.; Robbins, S.; Achanta, S.; Biscola, N. P.; Swid, M. A.; Rajendran, P. S.; Mori, S.; Hadaya, J.; Smith, E. H.; Peirce, S. G.; Chen, J.; Havton, L. A.; Cheng, Z.; Vadigepalli, R.; Schwaber, J.; Lux, R. L.; Efimov, I.; Tompkins, J. D.; Hoover, D. B.; Ardell, J. L.; Shivkumar, K.
10.1101/2020.10.28.359109 — neuroscience — Posted on 2020-10-29
345 Emergent collective organization of bone cells in complex curvature fields
Callens, S. J. P.; Fan, D.; van Hengel, I. A. J.; Minneboo, M.; Fratila-Apachitei, L. E.; Zadpoor, A. A.
10.1101/2020.10.28.358572 — bioengineering — Posted on 2020-10-29
347 Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes
Ansari-Pour, N.; Zheng, Y.; Pitt, J. J.; Dentro, S.; Yoshimatsu, T. F.; Sanni, A.; Ajani, M.; Woodard, A.; Rajagopal, P. S.; Fitzgerald, D.; Gruber, A. J.; Odetunde, A.; Popoola, A.; Falusi, A. G.; Babalola, C. P.; Ogundiran, T.; Obafunwa, J.; Ojengbede, O.; Ibrahim, N.; Barretina, J.; Van Loo, P.; Chen, M.; White, K. P.; Huo, D.; Wedge, D. C.; Olopade, O. I.
10.1101/2020.10.28.359240 — genomics — Posted on 2020-10-29
349 Deep learning classification of temporal data in ecology
Capinha, C.; Ceia-Hasse, A.; Kramer, A. M.; Meijer, C.
10.1101/2020.09.14.296251 — ecology — Posted on 2020-10-29
350 SWR1 Chromatin Remodeling Complex Prevents Mitotic Slippage during Spindle Position Checkpoint Arrest
Caydasi, A. K.; Khmelinskii, A.; Darieva, Z.; Kurtulmus, B.; Knop, M.; Pereira, G.
10.1101/749440 — cell biology — Posted on 2020-10-29
352 ATPase SRCAP is a new player in cell division, uncovering molecular aspects of Floating-Harbor syndrome
Messina, G.; Prozzillo, Y.; Delle Monache, F.; Santopietro, M. V.; Atterrato, M. T.; Dimitri, P.
10.1101/2020.09.12.294645 — cell biology — Posted on 2020-10-29
353 Apparent Reconsolidation Interference Without Generalized Amnesia
Alfei, J. M.; De Gruy, H.; De Bundel, D.; Luyten, L.; Beckers, T.
10.1101/2020.04.23.056952 — neuroscience — Posted on 2020-10-29
354 SIPEC: the deep-learning Swiss knife for behavioral data analysis
Marks, M.; Qiuhan, J.; Sturman, O.; von Ziegler, L.; Kollmorgen, S.; von der Behrens, W.; Mante, V.; Bohacek, J.; Yanik, M. F.
10.1101/2020.10.26.355115 — neuroscience — Posted on 2020-10-29
356 IFN-{lambda}4 may contribute to HCV persistence by increasing ER stress and enhancing IRF1 signaling
Onabajo, O. O.; Wang, F.; Lee, M.-H.; Florez-Vargas, O.; Obajemu, A.; Castro, M. A. A.; Tanikawa, C.; Vargas, J.; Liao, S.-F.; Song, C.; Huang, Y.-H.; Shen, C.-Y.; Banday, A. R.; O'Brien, T. R.; Hu, Z.; Matsuda, K.; Robertson, A. G.; Prokunina-Olsson, L.
10.1101/2020.10.28.359398 — cancer biology — Posted on 2020-10-29
357 Magnetoencephalographic Signatures of Conscious Processing Before Birth
Moser, J.; Schleger, F.; Weiss, M.; Sippel, K.; Semeia, L.; Preissl, H.
10.1101/2020.10.27.357129 — neuroscience — Posted on 2020-10-29
358 Dynamical consequences of regional heterogeneity in the brains transcriptional landscape
Deco, G.; Aquino, K. M.; Arnatkeviciute, A.; Oldham, S.; Sabaroedin, K.; Rogasch, N. C.; Kringelbach, M. L.; Fornito, A.
10.1101/2020.10.28.359943 — neuroscience — Posted on 2020-10-29
359 Brunner syndrome associated MAOA dysfunction in human dopaminergic neurons results in NMDAR hyperfunction and increased network activity.
Shi, Y.; van Rhijn, J.-R.; Bormann, M.; Mossink, B.; Frega, M.; Recaioglu, H.; Hakobjan, M.; Klein Gunnewiek, T. M.; Schoenmaker, C.; Palmer, E.; Faivre, L.; Kittel-Schneider, S.; Schubert, D.; Brunner, H.; Franke, B.; Nadif Kasri, N.
10.1101/2020.10.28.359224 — neuroscience — Posted on 2020-10-29
360 Neural substrates of verbal repetition deficits in primary progressive aphasia
Miller, H. E.; Cordella, C.; Collins, J. A.; Ezzo, R.; Quimby, M.; Hochberg, D.; Tourville, J. A.; Dickerson, B. C.; Guenther, F. H.
10.1101/2020.10.27.357038 — neuroscience — Posted on 2020-10-29
361 Mechanisms of allosteric and mixed mode aromatase inhibitors
Souza, S. A.; Held, A.; Lu, W.; Drouhard, B.; Avila, B.; Leyva-Montes, R.; Hu, M. G.; Miller, B. R.; Ng, H. L.
10.1101/2020.10.15.340745 — biochemistry — Posted on 2020-10-28
362 Somatic CAG expansion in Huntington's disease is dependent on the MLH3 endonuclease domain, which can be excluded via MLH3 splice redirection to suppress expansion
Roy, J. C. L.; Vitalo, A.; Andrew, M. A.; Mota-Silva, E.; Kovalenko, M.; Burch, Z.; Nhu, A. M.; Cohen, P. E.; Grabczyk, E.; Wheeler, V. C.; Mouro Pinto, R.
10.1101/2020.10.26.356238 — genetics — Posted on 2020-10-28
367 A GO catalogue of human DNA-binding transcription factors
Lovering, R. C.; Gaudet, P.; Acencio, M. L.; Ignatchenko, A.; Jolma, A.; Fornes, O.; Kuiper, M.; Kulakovskiy, I. V.; Laegreid, A.; Martin, M. J.; Logie, C.
10.1101/2020.10.28.359232 — bioinformatics — Posted on 2020-10-28
368 Longitudinal ultrasonic dimensions and parametric solid models of the gravid uterus and cervix
Louwagie, E. M.; Carlson, L.; Over, V.; Mao, L.; Fang, S.; Westervelt, A.; Vink, J.; Hall, T.; Feltovich, H.; Myers, K. M.
10.1101/2020.10.28.358812 — bioengineering — Posted on 2020-10-28
371 Activity, energy use and species identity affect eDNA shedding in freshwater fish
Thalinger, B.; Rieder, A.; Teuffenbach, A.; Putz, Y.; Schwerte, T.; Wanzenboeck, J.; Traugott, M.
10.1101/2020.10.28.359653 — ecology — Posted on 2020-10-28
375 Sirt1 overexpression attenuates high-fat diet induced aortic stiffening
Gogulamudi, V.; Machin, D. R.; Henson, G. D.; Donato, A. J.; Lesniewski, L. A.
10.1101/2020.10.28.358804 — physiology — Posted on 2020-10-28
376 Direct Measurement of Unsteady Microscale Stokes Flow Using Optically Driven Microspheres
Bruot, N.; Cicuta, P.; Gadelha, H.; Goldstein, R. E.; Kotar, J. E.; Lauga, E.; Nadal, F.
10.1101/2020.10.28.354738 — biophysics — Posted on 2020-10-28
377 Tumor Phylogeny Topology Inference via Deep Learning
Sadeqi Azer, E.; Haghir Ebrahimabadi, M.; Malikic, S.; Khardon, R.; Sahinalp, S. C.
10.1101/2020.02.07.938852 — bioinformatics — Posted on 2020-10-28
378 Emergent collective organization of bone cells in complex curvature fields
Callens, S.; Fan, D.; van Hengel, I.; Minneboo, M.; Fratila-Apachitei, L.; Zadpoor, A.
10.1101/2020.10.28.358572 — bioengineering — Posted on 2020-10-28
384 Physical properties of the cytoplasm modulate the rates of microtubule growth and shrinkage
Molines, A. T.; Lemiere, J.; Edrington, C. H.; Hsu, C.-T.; Steinmark, I. E.; Suhling, K.; Goshima, G.; Holt, L. J.; Brouhard, G.; Chang, F.
10.1101/2020.10.27.352716 — cell biology — Posted on 2020-10-28
385 Epitomic analysis of the specificity of conformation-dependent, anti-aβ amyloid monoclonal antibodies
Reyes-Ruiz, J. M.; Nakajima, R.; Baghallab, I.; Goldschmidt, L.; Sosna, J.; Ho, P. N. M.; Kumosani, T.; Felgner, P. L.; Glabe, C. G.
10.1101/2020.08.05.238105 — neuroscience — Posted on 2020-10-28
386 Modularity and neural coding from a brainstem synaptic wiring diagram
Vishwanathan, A.; Ramirez, A.; Wu, J.; Sood, A.; Yang, R.; Kemnitz, N.; Ih, D.; Turner, N.; Lee, K.; Tartavull, I.; Silversmith, W. M.; Jordan, C. S.; David, C.; Bland, D.; Goldman, M. S.; Aksay, E.; Seung, H. S.
10.1101/2020.10.28.359620 — neuroscience — Posted on 2020-10-28
391 Structural insights into the cooperative interaction of the intrinsically disordered co-activator TIF2 with retinoic acid receptor heterodimer (RXR/RAR)
Senicourt, L.; le Maire, A.; Allemand, F.; Carvalho, J. E.; Guee, L.; Germain, P.; Schubert, M.; Bernado, P.; Bourguet, W.; Sibille, N.
10.1101/2020.10.28.359091 — biophysics — Posted on 2020-10-28
392 Label-free cell viability assay using phase imaging with computational specificity
Hu, C.; He, S.; Lee, Y. J.; He, Y.; Kong, E. M.; Li, H.; Anastasio, M. A.; Popescu, G.
10.1101/2020.10.28.359554 — bioengineering — Posted on 2020-10-28
394 APOEε3/ε4 and APOEε4/ε4 genotypes drive unique gene signatures in the cortex of young mice
Foley, K. E.; Garceau, D. T.; Kotredes, K. P.; Carter, G. W.; Sasner, M.; Howell, G. R.
10.1101/2020.10.28.359422 — genomics — Posted on 2020-10-28
397 New Genes in Drosophila Quickly Evolved Essential Functions in Viability During Development
Xia, S.; VanKuren, N. W.; Chen, C.; Zhang, L.; Kemkemer, C.; Shao, Y.; Jia, H.; Lee, U.; Advani, A. S.; Gschwend, A.; Vibranovski, M.; Chen, S.; Zhang, Y. E.; Long, M.
10.1101/2020.10.27.357848 — developmental biology — Posted on 2020-10-28
399 Ethacridine inhibits SARS-CoV-2 by inactivating viral particles in cellular models
Li, X.; Lidsky, P.; Xiao, Y.; Wu, C.-T.; Garcia-Knight, M.; Yang, J.; Nakayama, T.; Nayak, J. V.; Jackson, P. K.; Andino, R.; Shu, X.
10.1101/2020.10.28.359042 — microbiology — Posted on 2020-10-28
400 SARS-CoV-2 replication triggers an MDA-5-dependent interferon production which is unable to efficiently control replication
Rebendenne, A.; Chaves Valadao, A. L.; Tauziet, M.; Maarifi, G.; Bonaventure, B.; Planes, R.; McKellar, J.; Nisole, S.; Arnaud-Arnould, M.; Moncorge, O.; Goujon, C.
10.1101/2020.10.28.358945 — microbiology — Posted on 2020-10-28
401 Regulation of retinal amacrine cell generation by miR-216b and Foxn3
Zhang, H.; Zhuang, P.; Welchko, R. M.; Dai, M.; Meng, F.; Turner, D. L.
10.1101/2020.10.28.358069 — neuroscience — Posted on 2020-10-28
405 Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones
Ahmad, S.; Tsang, K. K.; Sachar, K.; Quentin, D.; Tashin, T. M.; Bullen, N. P.; Raunser, S.; McArthur, A. G.; Prehna, G.; Whitney, J. C.
10.1101/2020.10.28.356139 — biochemistry — Posted on 2020-10-28
406 Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes
Ansari-Pour, N.; Zheng, Y.; Pitt, J. J.; Dentro, S.; Yoshimatsu, T. F.; Sanni, A.; Ajani, M.; Woodard, A.; Rajagopal, P. S.; Fitzgerald, D.; Gruber, A. J.; Odetunde, A.; Popoola, A.; Falusi, A. G.; Babalola, C. P.; Ogundiran, T.; Obafunwa, J.; Ojengbede, O.; Ibrahim, N.; Barretina, J.; Van Loo, P.; Chen, M.; White, K. P.; Huo, D.; Wedge, D. C.; Olopade, O. I.
10.1101/2020.10.28.359240 — genomics — Posted on 2020-10-28
409 High dose IFN-β activates GAF to enhance expression of ISGF3 target genes in epithelial cells
Kishimoto, K.; Wilder, C.; Buchanan, J.; Nguyen, M.; Okeke, C.; Hoffmann, A.; Cheng, Q. J.
10.1101/2020.10.28.358366 — molecular biology — Posted on 2020-10-28
412 5-amino levulinic acid inhibits SARS-CoV-2 infection in vitro
Sakurai, Y.; Tun, M. M. N.; Kurosaki, Y.; Sakura, T.; Inaoka, D. K.; Fujine, K.; Kita, K.; Morita, K.; Yasuda, J.
10.1101/2020.10.28.355305 — microbiology — Posted on 2020-10-28
413 SARS-CoV-2 desensitizes host cells to interferon through inhibition of the JAK-STAT pathway
Chen, D.-Y.; Khan, N.; Close, B. J.; Goel, R. K.; Blum, B.; Tavares, A. H.; Kenney, D.; Conway, H. L.; Ewoldt, J. K.; Kapell, S.; Chitalia, V. C.; Crossland, N. A.; Chen, C. S.; Kotton, D. N.; Baker, S. C.; Connor, J. H.; Douam, F.; Emili, A.; Saeed, M.
10.1101/2020.10.27.358259 — microbiology — Posted on 2020-10-28
416 Gamma-irradiated SARS-CoV-2 vaccine candidate, OZG-38.61.3, confers protection from SARS-CoV-2 challenge in human ACEII-transgenic mice
Turan, R. D.; Tastan, C.; Dilek Kancagi, D.; Yurtsever, B.; Sir Karakus, G.; Ozer, S.; Abanuz, S.; Cakirsoy, D.; Tumentemur, G.; Demir, S.; Seyis, U.; Kuzay, R.; Elek, M.; Ertop, G.; Arbak, S.; Acikel Elmas, M.; Hemsinlioglu, C.; Hatirnaz Ng, O.; Akyoney, S.; Sahin, I.; Kayhan, C. K.; Tokat, F.; Akpinar, G.; Kasap, M.; Kocagoz, A. S.; Ozbek, U.; Telci, D.; Sahin, F.; Yalcin, K.; Ratip, S.; Ince, U.; Suyen, G.; Ovali, E.
10.1101/2020.10.28.356667 — immunology — Posted on 2020-10-28
418 A Microglial Subset at the Tumor-Stroma Interface of Glioma
Caponegro, M. D.; Oh, K.; Madeira, M.; Radin, D.; Sterge, N.; Moffitt, R. A.; Tsirka, S. E.
10.1101/2020.10.27.357459 — neuroscience — Posted on 2020-10-28
420 Altered neural oscillations and behavior in a genetic mouse model of NMDA receptor hypofunction
Aguilar, D. D.; Radzik, L. K.; Schiffino, F. L.; Folorunso, O.; Zielinski, M. R.; Coyle, J. T.; Balu, D. T.; McNally, J. M.
10.1101/2020.10.28.359547 — neuroscience — Posted on 2020-10-28
422 Revealing tissue-specific metabolic crosstalk after a myocardial infarction
Arif, M.; Klevstig, M.; Benfeitas, R.; Doran, S.; Turkez, H.; Uhlen, M.; Clausen, M.; Wikström, J.; Etal, D.; Zhang, C.; Levin, M.; Mardinoglu, A.; Boren, J.
10.1101/2020.10.28.358556 — systems biology — Posted on 2020-10-28
423 Wing shape evolution in bombycoid moths reveals two distinct strategies for maneuverable flight
Aiello, B. R.; Sikandar, U. B.; Minoguchi, H.; Kimball, K.; Hamilton, C. A.; Kawahara, A. Y.; Sponberg, S.
10.1101/2020.10.27.358176 — physiology — Posted on 2020-10-28
425 Detecting Insulitis in Type 1 Diabetes with Ultrasound Phase-change Contrast Agents
Ramirez, D. G.; Upadhyay, A. K.; Pham, V. T.; Ciccaglione, M.; Borden, M. A.; Benninger, R. K.
10.1101/2020.10.28.359687 — bioengineering — Posted on 2020-10-28
426 Mechanism of SARS-CoV-2 polymerase inhibition by remdesivir
Kokic, G.; Hillen, H. S.; Tegunov, D.; Dienemann, C.; Seitz, F.; Schmitzova, J.; Farnung, L.; Siewert, A.; Hoebartner, C.; Cramer, P.
10.1101/2020.10.28.358481 — biochemistry — Posted on 2020-10-28
428 A novel family of secreted proteins linked to plant gall development
Korgaonkar, A.; Han, C.; Lemire, A. L.; Siwanowicz, I.; Bennouna, D.; Kopec, R.; Andolfatto, P.; Shigenobu, S.; Stern, D. L.
10.1101/2020.10.28.359562 — genetics — Posted on 2020-10-28
429 DNAJB12 and Hsp70 Facilitate the Conformation Specific Degradation of Arrested N1303K-CFTR Intermediates by ERQC-Autophagy
He, L.; Kennedy, A. S.; Houck, S.; Aleksandrov, A. A.; Quinney, N. L.; Gentzsch, M.; Cholon, D.; Randell, S. H.; Ren, H. Y.; Cyr, D. M.
10.1101/2020.10.28.358580 — cell biology — Posted on 2020-10-28
430 Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells
Cromer, M. K.; Camarena, J.; Martin, R. M.; Lesch, B. J.; Vakulskas, C. A.; Lemgart, V. T.; Zhang, Y.; Goyal, A.; Zhao, F.; Ponce, E.; Srifa, W.; Bak, R. O.; Uchida, N.; Majeti, R.; Sheehan, V. A.; Tisdale, J. F.; Dever, D. P.; Porteus, M.
10.1101/2020.10.28.359315 — molecular biology — Posted on 2020-10-28
431 Aglycone polyether ionophores as broad-spectrum agents inhibit multiple enveloped viruses including SARS-CoV-2 in vitro and successfully cure JEV infected mice
Liu, T.; Li, J.-Q.; Huang, M.; Zhang, Y.-N.; Liu, R.; Zhang, Z.-R.; Zhang, Q.-Y.; Wang, Y.; Liu, J.; Deng, Z.; Zhang, B.; Ye, H.-Q.
10.1101/2020.10.27.354563 — microbiology — Posted on 2020-10-28
432 VirION2: a short- and long-read sequencing and informatics workflow to study the genomic diversity of viruses in nature
Zablocki, O.; Michelsen, M.; Burris, M.; Solonenko, N.; Warwick-Dugdale, J.; Ghosh, R.; Pett-Ridge, J.; Sullivan, M. B.; Temperton, B.
10.1101/2020.10.28.359364 — microbiology — Posted on 2020-10-28
433 Waffle method: A general and flexible approach for FIB-milling small and anisotropically oriented samples
Kelley, K.; Jaroenlak, P.; Raczkowski, A. M.; Eng, E. T.; Bhabha, G.; Potter, C. S.; Carragher, B.; Noble, A. J.
10.1101/2020.10.28.359372 — microbiology — Posted on 2020-10-28
434 A genome-wide CRISPR/Cas9 knock-out screen identifies the DEAD box RNA helicase DDX42 as a broad antiviral inhibitor
Bonaventure, B.; Rebendenne, A.; Garcia de Gracia, F.; Tauziet, M.; McKellar, J.; Chaves Valadao, A. L.; Courgnaud, V.; Bernard, E.; Briant, L.; Gros, N.; Djilli, W.; Arnaud-Arnould, M.; Parrinello, H.; Rialle, S.; Moncorge, O.; Goujon, C.
10.1101/2020.10.28.359356 — microbiology — Posted on 2020-10-28
435 Magnitude and kinetics of T cell and antibody responses during H1N1pdm09 infection in outbred and inbred Babraham pigs
Edmans, M.; Mcnee, A.; Porter, E.; Vatzia, E.; Paudyal, B.; Martini, V.; Gubbins, S.; Francis, O.; Harley, R.; Thomas, A.; Burt, R.; Morgan, S.; Fuller, A.; Sewell, A.; Charleston, B.; Bailey, M.; Tchilian, E.
10.1101/2020.10.28.346767 — immunology — Posted on 2020-10-28
436 Induced pulmonary comorbidities render CD-1 mice sensitive to SARS-CoV-2
Falach, R.; Bar-On, L.; Lazar, S.; Kadar, T.; Mazor, O.; Aftalion, M.; Gur, D.; Shifman, O.; Israeli, O.; Cohen-Gihon, I.; Zaida, G.; Gutman, H.; Evgy, Y.; Vagima, Y.; Makdasi, E.; Stein, D.; Rosenfeld, R.; Alcalay, R.; Zahavy, E.; Levy, H.; Glinert, I.; Ben-Shmuel, A.; Israely, T.; Melamed, S.; Politi, B.; Achdout, H.; Yitzhaky, S.; Kronman, C.; Sabo, T.
10.1101/2020.10.28.358614 — pathology — Posted on 2020-10-28
438 DTI reveals whole-brain microstructural changes in the P301L mouse model of tauopathy
Massalimova, A.; Ni, R.; Nitsch, R. M.; Reisert, M.; von Elverfeldt, D.; Klohs, J.
10.1101/2020.10.28.358465 — neuroscience — Posted on 2020-10-28
440 Modulating Intra-Nuclear LC3 with Small Molecules Rescues Cells from a Docetaxel-Induced Phenotype
Rosenberg, D. P.; Kolla, L.; Heo, D.; Cassio, E.; Veenstra, M. J.; Vakaki, M.; Zhang, J.; Anyetei-Anum, C.; Allison, L. A.; Buchser, W. J.
10.1101/2020.10.28.355826 — molecular biology — Posted on 2020-10-28
445 The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase
Alhammad, Y. M. O.; Kashipathy, M. M.; Roy, A.; Gagne, J.-P.; McDonald, P.; Gao, P.; Nonfoux, L.; Battaile, K. P.; Johnson, D. K.; Holmstrom, E. D.; Poirier, G. G.; Lovell, S. W.; Fehr, A. R.
10.1101/2020.05.11.089375 — biochemistry — Posted on 2020-10-28
446 Atlas of genetic effects in human microglia transcriptome across brain regions, aging and disease pathologies
de Paiva Lopes, K.; Snijders, G. J. L.; Humphrey, J.; Allan, A.; Sneeboer, M.; Navarro, E.; Schilder, B. M.; Vialle, R. A.; Parks, M.; Missall, R.; van Zuiden, W.; Gigase, F.; Kübler, R.; Berdenis van Berlekom, A.; Böttcher, C.; Priller, J.; Kahn, R. S.; de Witte, L. D.; Raj, T.
10.1101/2020.10.27.356113 — genetics — Posted on 2020-10-28
448 High neutralizing potency of swine glyco-humanized polyclonal antibodies against SARS-CoV-2
Vanhove, B.; Duvaux, O.; Rousse, J.; Royer, P.-J.; Evanno, G.; Ciron, C.; Lheriteau, E.; Vacher, L.; Gervois, N.; Oger, R.; Jacques, Y.; Conchon, S.; Salama, A.; Duchi, R.; Lagutina, I.; Perota, A.; Delahaut, P.; Ledure, M.; Paulus, M.; So, R.; Mok, C. K. P.; Bruzzone, R.; Bouillet, M.; Brouard, S.; Cozzi, E.; Galli, C.; Blanchard, D.; Bach, J.-M.; Soulillou, J.-P.
10.1101/2020.07.25.217158 — immunology — Posted on 2020-10-28
449 Phosphorylation triggers presynaptic phase separation of Liprin-α3 to control active zone structure
Emperador Melero, J.; Wong, M. Y.; Wang, S. S. H.; De Nola, G.; Kirchhausen, T.; Kaeser, P. S.
10.1101/2020.10.28.357574 — neuroscience — Posted on 2020-10-28
450 Asynchrony between virus diversity and antibody selection limits influenza virus evolution
Morris, D. H.; Petrova, V. N.; Rossine, F. W.; Parker, E.; Grenfell, B. T.; Neher, R.; Levin, S. A.; Russell, C. A.
10.1101/2020.04.27.064915 — evolutionary biology — Posted on 2020-10-28
451 Lateral and longitudinal fish eDNA distribution in dynamic riverine habitats
Thalinger, B.; Kirschner, D.; Putz, Y.; Moritz, C.; Schwarzenberger, R.; Wanzenboeck, J.; Traugott, M.
10.1101/2020.05.28.120147 — ecology — Posted on 2020-10-28
452 Repeat DNA-PAINT suppresses background and non-specific signals in optical nanoscopy
Clowsley, A. H.; Kaufhold, W. T.; Lutz, T.; Meletiou, A.; Di Michele, L.; Soeller, C.
10.1101/2020.04.24.059410 — molecular biology — Posted on 2020-10-28
453 Early life stress programming of NG2+ glia transcriptome alters functional properties of voltage gated sodium (Nav) channels and cognitive performance
Treccani, G.; Yigit, H.; Lingner, T.; Schleussner, V.; Wennstrom, M.; Herzog, D. P.; Fricke, M.; Wegener, G.; Mittmann, T.; Trotter, J.; Muller, M.
10.1101/2020.08.19.257113 — neuroscience — Posted on 2020-10-28
456 COVID-19 Disease Map, a computational knowledge repository of SARS-CoV-2 virus-host interaction mechanisms
Ostaszewski, M.; Niarakis, A.; Mazein, A.; Kuperstein, I.; Phair, R.; Orta-Resendiz, A.; Singh, V.; Aghamiri, S. S.; Acencio, M. L.; Glaab, E.; Ruepp, A.; Fobo, G.; Montrone, C.; Brauner, B.; Frishman, G.; Monraz Gomez, L. C.; Somers, J.; Hoch, M.; Gupta, S. K.; Scheel, J.; Borlinghaus, H.; Czauderna, T.; Schreiber, F.; Montagud, A.; Ponce de Leon, M.; Funahashi, A.; Hiki, Y.; Hiroi, N.; Yamada, T. G.; Drager, A.; Renz, A.; Naveez, M.; Bocskei, Z.; Messina, F.; Bornigen, D.; Fergusson, L.; Conti, M.; Rameil, M.; Nakonecnij, V.; Vanhoefer, J.; Schmiester, L.; Wang, M.; Ackerman, E. E.; Shoemake
10.1101/2020.10.26.356014 — systems biology — Posted on 2020-10-28
457 An exploration of assembly strategies and quality metrics on the accuracy of the Knightia excelsa (rewarewa) genome.
McCartney, A.; Hilario, E.; Choi, S.-S.; Guhlin, J.; Prebble, J.; Houliston, G.; Buckley, T. R.; Chagne, D.
10.1101/2020.10.28.358903 — genomics — Posted on 2020-10-28
458 GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells
Fernandez, R. J.; Gardner, Z. J. G.; Slovik, K. J.; Liberti, D. C.; Estep, K. N.; Yang, W.; Chen, Q.; Santini, G. T.; Perez, J. V.; Root, S.; Bhatia, R.; Tobias, J. W.; Babu, A.; Morley, M. P.; Frank, D. B.; Morrisey, E. E.; Lengner, C. J.; Johnson, F. B.
10.1101/2020.10.28.358887 — cell biology — Posted on 2020-10-28
461 Ultrastructural view of astrocyte-astrocyte and astrocyte-synapse contacts within the hippocampus
Kiyoshi, C. M.; Aten, S.; Arzola, E. P.; Patterson, J. A.; Taylor, A. T.; Du, Y.; Guiher, A. M.; Philip, M.; Camacho, E. G.; Mediratta, D.; Collins, K.; Benson, E.; Kidd, G.; Terman, D.; Zhou, M.
10.1101/2020.10.28.358200 — neuroscience — Posted on 2020-10-28
462 Depletion of senescent cells improves functional recovery after spinal cord injury
Paramos-de-Carvalho, D.; Martins, I.; Cristovao, A. M.; Dias, A. F.; Neves-Silva, D.; Pereira, T.; Chapela, D.; Farinho, A.; Jacinto, A.; Saude, L.
10.1101/2020.10.28.358762 — neuroscience — Posted on 2020-10-28
463 Genetically-Modified Macrophages Accelerate Myelin Repair
Tepavcevic, V.; Dufayet-Chaffaud, G.; Aigrot, M.-S.; Gillet-Legrand, B.; Tada, S.; Izagirre, L.; Cartier, N.; Lubetzki, C.
10.1101/2020.10.28.358705 — neuroscience — Posted on 2020-10-28
467 Cycling hypoxia selects for constitutive HIF stabilization
Pressley, M.; Gallaher, J. A.; Brown, J. S.; Tomaszewski, M. R.; Borad, P.; Damaghi, M.; Gillies, R. J.; Whelan, C. J.
10.1101/2020.10.28.359018 — cancer biology — Posted on 2020-10-28
468 Nature of active forces in tissues: how contractile cells can form extensile monolayers
Balasubramaniam, L.; Doostmohammadi, A.; Saw, T. B.; Sankara, G.; Mueller, R.; Dang, T.; Thomas, M.; Gupta, S.; Sonam, S.; Yap, A. S.; Toyama, Y.; Mege, R.-M.; Yeomans, J.; Ladoux, B.
10.1101/2020.10.28.358663 — biophysics — Posted on 2020-10-28
472 Assortative mating, autistic traits, empathizing, and systemizing
Richards, G.; Baron-Cohen, S.; Stokes, H.; Warrier, V.; Mellor, B.; Winspear, E.; Davies, J.; Gee, L.; Galvin, J.
10.1101/2020.10.28.358895 — evolutionary biology — Posted on 2020-10-28
474 Exon Junction Complex dependent mRNA localization is linked to centrosome organization during ciliogenesis
KWON, O. S.; MISHRA, R. K.; SAFIEDDINE, A.; ALASSEUR, Q.; FAUCOURT, M.; COLENO, E.; BARBOSA, I.; BERTRAND, E.; SPASSKY, N.; LE HIR, H.
10.1101/2020.10.28.358960 — cell biology — Posted on 2020-10-28
475 Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability
Wang, L.; Astone, M.; Alam, S. K.; Zhu, Z.; Pei, W.; Frank, D. A.; Burgess, S. M.; Hoeppner, L. H.
10.1101/2020.10.27.358374 — molecular biology — Posted on 2020-10-28
478 In-vitro and in-vivo characterization of CRANAD-2 for multi-spectral optoacoustic tomography and fluorescence imaging of amyloid-beta deposits in Alzheimer mice
Ni, R.; Villois, A.; Dean-Ben, X. L.; Chen, Z.; Vaas, M.; Stavrakis, S.; Shi, G.; deMello, A.; Ran, C.; Razansky, D.; Arosio, P.; Klohs, J.
10.1101/2020.10.27.353862 — neuroscience — Posted on 2020-10-28
481 Targeting C5aR1 Increases the Therapeutic Window of Radiotherapy
Olcina, M. M.; Melemenidis, S.; Nambiar, D. K.; Kim, R. K.; Casey, K. M.; von Eyben, R.; Woodruff, T. M.; Graves, E. G.; Le, Q.-T.; Stucki, M.; Giaccia, A. J.
10.1101/2020.10.27.358036 — cancer biology — Posted on 2020-10-28
484 A Darwinian outlook on schistosomiasis elimination
Van den Broeck, F.; Vanoverbeke, J.; Polman, K.; Huyse, T.
10.1101/2020.10.28.358523 — genetics — Posted on 2020-10-28
485 Multiple spatial behaviours govern social network positions in a wild ungulate
Albery, G. F.; Morris, A.; Morris, S.; Pemberton, J. M.; Clutton-Brock, T. H.; Nussey, D. H.; Firth, J. A.
10.1101/2020.06.04.135467 — ecology — Posted on 2020-10-28
486 Cytoplasm Biophysical Properties Modulate rates of microtubule growth and shrinkage
Molines, A. T.; Lemiere, J.; Edrington, C. H.; Hsu, C.-T.; Steinmark, I. E.; Suhling, K.; Goshima, G.; Holt, L. J.; Brouhard, G.; Chang, F. T.
10.1101/2020.10.27.352716 — cell biology — Posted on 2020-10-28
487 Reverse Genetics with a Full-length Infectious cDNA Clone of Bovine Torovirus
Ujike, M.; Etoh, Y.; Urushiyama, N.; Taguchi, F.; Enjuanes, L.; Kamitani, W.
10.1101/2020.10.28.358754 — microbiology — Posted on 2020-10-28
488 Predictive modeling of virus inactivation by UV
Rockey, N. C.; Chin, K.; Henderson, J. B.; Raskin, L.; Wigginton, K.
10.1101/2020.10.27.355479 — microbiology — Posted on 2020-10-28
489 Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction
Mainali, R.; Zabalwi, M.; Long, D.; Buechler, N.; Quillen, E.; Key, C.-C.; Zhu, X.; Parks, J.; Furdui, C.; Stacpoole, P.; Martinez, J.; McCall, C. E.; Quinn, M. A.
10.1101/2020.06.09.142430 — immunology — Posted on 2020-10-28
490 Altered kinetics of circulating progenitor cells in cardiopulmonary bypass (CPB) associated vasoplegic patients: A pilot study
Nandi, S.; Potunuru, U. R.; Kumari, C.; Nathan, A. A.; Gopal, J.; Menon, G. I.; Siddharthan, R.; Dixit, M.; Thangaraj, P. R.
10.1101/2020.03.11.987099 — physiology — Posted on 2020-10-28
491 Species level resolution of female bladder microbiota from marker gene surveys
Hoffman, C.; Siddiqui, N. Y.; Fields, I.; Gregory, W. T.; SImon, H.; Mooney, M. A.; Wolfe, A. J.; Karstens, L.
10.1101/2020.10.27.358408 — bioinformatics — Posted on 2020-10-28
495 Restructuring of genomic provinces of surface ocean plankton under climate change
Fremont, P.; Gehlen, M.; Vrac, M.; Leconte, J.; Wincker, P.; Iudicone, D.; Jaillon, O.
10.1101/2020.10.20.347237 — ecology — Posted on 2020-10-28
497 Loss of heterochromatin and retrotransposon silencing constitute an early phase in oocyte aging
Wasserzug-Pash, P.; Rothman, R.; Riech, E.; Schonberger, O.; Weiss, Y.; Srebnik, N.; Weintraub, A.; Ben-Ami, I.; Holzer, H.; Klutstein, M.
10.1101/2020.10.28.358440 — cell biology — Posted on 2020-10-28
498 Multiple Holins Contribute to Extracellular DNA Release in Pseudomonas aeruginosa Biofilms
Hynen, A. L.; Lazenby, J. J.; Savva, G. M.; McCaughey, L. C.; Turnbull, L.; Nolan, L. M.; Whitchurch, C. B.
10.1101/2020.10.28.358747 — microbiology — Posted on 2020-10-28
500 Self-Reported Sleep Relates to Microstructural Hippocampal Decline in β-Amyloid Positive Adults Beyond Genetic Risk
Grydeland, H.; Sederevicius, D.; Wang, Y.; Bartres-Faz, D.; Bertram, L.; Dobricic, V.; Düzel, S.; Ebmeier, K. P.; Lindenberger, U.; Nyberg, L.; Pudas, S.; Sexton, C. E.; Sole-Padulles, C.; Walhovd, K. B.; Fjell, A. M.
10.1101/2020.04.28.061184 — neuroscience — Posted on 2020-10-28
504 Convergent evolution of Streptomyces protease inhibitors involving a tRNA-mediated condensation-minus NRPS
Aguilar, C.; Verdel-Aranda, K.; Ramos-Aboites, H. E.; Morales, M. A.; Licona-Cassani, C.; Barona-Gomez, F.
10.1101/2020.10.26.356543 — microbiology — Posted on 2020-10-28
505 Lipidomic profiling of clinical prostate cancer reveals targetable alterations in lipid composition
Butler, L. M.; Mah, C. Y.; Machiels, J.; Vincent, A. D.; Irani, S.; Mutuku, S.; Spotbeen, X.; Bagadi, M.; Waltregny, D.; Moldovan, M.; Dehairs, J.; Vanderhoydonc, F.; Bloch, K.; Das, R.; Stahl, J.; Kench, J.; Gevaert, T.; Derua, R.; Waelkens, E.; Nassar, Z. D.; Selth, L. A.; Trim, P. J.; Snel, M. F.; Lynn, D. J.; Tilley, W. D.; Horvath, L. G.; Centenera, M. M.; Swinnen, J. V.
10.1101/2020.10.27.356634 — cancer biology — Posted on 2020-10-28
507 Structural differences in translation initiation between pathogenic trypanosomatids and their mammalian hosts
Bochler, A.; Brito Querido, J.; Prilepskaja, T.; Soufari, H.; Lucia Del Cistia, M.; Kuhn, L.; Rimoldi Ribeiro, A.; Valasek, L. S.; Hashem, Y.
10.1101/806141 — molecular biology — Posted on 2020-10-28
508 Bayesian model selection favors parametric over categorical fMRI subsequent memory models in young and older adults
Soch, J.; Richter, A.; Schuetze, H.; Kizilirmak, J. M.; Assmann, A.; Knopf, L.; Raschick, M.; Schult, A.; Maass, A.; Ziegler, G.; Richardson-Klavehn, A.; Duezel, E.; Schott, B. H.
10.1101/2020.07.27.220871 — neuroscience — Posted on 2020-10-28
509 Schlafen family member 5 (SLFN5) regulates LAT1-mediated mTOR activation in castration-resistant prostate cancer
Martinez, R. S.; Salji, M. J.; Rushworth, L.; Ntala, C.; Rodriguez Blanco, G.; Hedley, A.; Clark, W.; Peixoto, P.; Hervouet, E.; Renaude, E.; Kung, S. H.; Galbraith, L. C.; Nixon, C.; Lilla, S.; MacKay, G. M.; Fazli, L.; Sumpton, D.; Gleave, M. E.; Zanivan, S. R.; Blomme, A.; Leung, H. Y.
10.1101/2020.09.17.301283 — cancer biology — Posted on 2020-10-28
510 Experimental and mathematical modelling of magnetically labelled mesenchymal stromal cell delivery
Yeo, E. F.; Markides, H.; Schade, A. T.; Studd, A. J.; Oliver, J. M.; Waters, S. L.; El Haj, A. J.
10.1101/2020.10.27.356725 — bioengineering — Posted on 2020-10-28
512 Expansion of frozen hybrids in the guppy ectoparasite, Gyrodactylus turnbulli
Konczal, M.; Przesmycka, K.; Mohammed, R. S.; Hahn, C.; Cable, J.; Radwan, J.
10.1101/2020.04.02.021329 — evolutionary biology — Posted on 2020-10-28
517 Selective and Improved Photoannealing of Microporous Annealed Particle (MAP) Scaffolds
Pfaff, B. N.; Pruett, L. J.; Cornell, N. J.; De Rutte, J.; DiCarlo, D.; Highley, C.; Griffin, D. R.
10.1101/2020.10.27.358127 — bioengineering — Posted on 2020-10-28
518 Genetic landscape of recessive diseases in the Vietnamese population from large-scale clinical exome sequencing
Tran, N. H.; Nguyen Thi, T.-H.; Tang, H.-S.; Hoang, L.-P.; Nguyen, T.-H. L.; Tran, N.-T.; Trinh, T.-H. N.; Nguyen, V. T.; Nguyen, B.-H. H.; Nguyen, H. T.; Doan, L. P.; Phan, N.-M.; Nguyen, K.-H. T.; Nguyen, H.-D. L.; Quach, M.-T. T.; Nguyen, T.-P. T.; Tran, V. U.; Tran, D.-V.; Nguyen, Q.-T. T.; Do, T.-T. T.; Lam, N. V.; Cao Thi Ngoc, P.; Truong, D. K.; Nguyen, H.-N.; Phan, M.-D.; Giang, H.
10.1101/2020.10.27.358358 — genetics — Posted on 2020-10-28
519 Shrinking of fish under warmer temperatures decrease dispersal abilities and speciation rates
Avaria-Llautureo, J.; Venditti, C.; Rivadeneira, M. M.; Inonstroza-Michael, O.; Rivera, R. J.; Hernandez, C. E.; Canales-Aguirre, C. B.
10.1101/2020.10.27.357236 — evolutionary biology — Posted on 2020-10-28
522 Genomic Diversity in a Population of Spodoptera frugiperda Nucleopolyhedrovirus
Masson, T.; Fabre, M. L.; Pidre, M. L.; Niz, J. M.; Berretta, M. F.; Romanowski, V.; Ferrelli, M. L.
10.1101/2020.10.27.358317 — microbiology — Posted on 2020-10-28
523 Modeling PPRV pathogenesis in mice to assess the contribution of innate cells and anti-viral T cells
Sharma, Y.; Sarkar, R.; Jain, A.; Singh, S.; Shekhar, C.; Shanmugam, C.; Dhanavelu, M.; Tembure, P.; Kaul, R.; Sehrawat, S.
10.1101/2020.10.27.358309 — immunology — Posted on 2020-10-28
526 Counterfactual Hypothesis Testing of Tumor Microenvironment Scenarios Through Semantic Image Synthesis
Li, D.; Ma, Q.; Chen, J. L.; Liu, A.; Cheung, J.; Xie, Y.; Gudjonson, H.; Nawy, T.; Pe'er, D.; Pe'er, I.
10.1101/2020.10.27.358101 — cancer biology — Posted on 2020-10-28
530 Spatially expandable fiber-based probes as a multifunctional deep brain interface
Jiang, S.; Patel, D. C.; Kim, J.; Yang, S.; Mills, W.; Zhang, Y.; Wang, K.; Feng, Z.; Vijayan, S.; Cai, W.; Wang, A.; Guo, Y.; Kimbrough, I. F.; Sontheimer, H.; Jia, X.
10.1101/2020.10.27.355768 — bioengineering — Posted on 2020-10-28
531 Development and validation of an open-source, disposable, 3D-printed in vitro environmental exposure system for Transwell culture inserts
Chandiramohan, A.; Dabaghi, M.; Aguiar, J.; Tiessen, N.; Stewart, M.; Cao, Q.; Nguyen, J.; Makhdami, N.; Cox, G.; Doxey, A.; Hirota, J. A.
10.1101/2020.10.27.358168 — bioengineering — Posted on 2020-10-28
532 Polymorphic SINEC_Cf Retrotransposons in the Genome of the Dog (Canis familiaris)
Kalla, S. E.; Moghadam, H. K.; Tomlinson, M.; Seebald, A.; Allen, J. J.; Whitney, J.; Choi, J. D.; Sutter, N. B.
10.1101/2020.10.27.358119 — genomics — Posted on 2020-10-28
533 Rooting the animal tree of life
Li, Y.; Shen, X.-X.; Evans, B.; Dunn, C. W.; Rokas, A.
10.1101/2020.10.27.357798 — evolutionary biology — Posted on 2020-10-28
534 PhyKIT: a UNIX shell toolkit for processing and analyzing phylogenomic data
Steenwyk, J. L.; Buida, T. J.; LaBella, A. L.; Li, Y.; Shen, X.-X.; Rokas, A.
10.1101/2020.10.27.358143 — evolutionary biology — Posted on 2020-10-28
535 The mutability of demographic noise in microbial range expansions
Yu, Q.; Gralka, M.; Duvernoy, M.-C.; Sousa, M.; Harpak, A.; Hallatschek, O.
10.1101/2020.10.27.357483 — evolutionary biology — Posted on 2020-10-28
539 The PfAP2-G2 transcription factor is a critical regulator of gametocyte maturation
Singh, S.; Santos, J. M.; Orchard, L. M.; Yamada, N.; van Biljon, R.; Painter, H. J.; Mahony, S.; Llinas, M.
10.1101/2020.10.27.355685 — microbiology — Posted on 2020-10-28
540 The neural circuitry underlying the "rhythm effect" in stuttering
Frankford, S. A.; Heller Murray, E. S.; Masapollo, M.; Cai, S.; Tourville, J. A.; Nieto-Castanon, A.; Guenther, F. H.
10.1101/2020.10.27.350975 — neuroscience — Posted on 2020-10-28
541 Spatial modulation of dark versus bright stimulus responses in mouse visual cortex
Williams, B.; Del Rosario, J.; Coletta, S.; Murlin, E. K.; Muzzu, T.; Speed, A.; Meyer-Baese, L.; Saleem, A. B.; Haider, B.
10.1101/2020.10.27.353573 — neuroscience — Posted on 2020-10-28
542 Neuropixels 2.0: A miniaturized high-density probe for stable, long-term brain recordings
Steinmetz, N. A.; Aydin, C.; Lebedeva, A.; Okun, M.; Pachitariu, M.; Bauza, M.; Beau, M.; Bhagat, J.; Böhm, C.; Broux, M.; Chen, S.; Colonell, J.; Gardner, R. J.; Karsh, B.; Kostadinov, D.; Mora-Lopez, C.; Park, J.; Putzeys, J.; Sauerbrei, B. A.; van Daal, R. J. J.; Vollan, A. Z.; Welkenhuysen, M.; Ye, Z.; Dudman, J. T.; Dutta, B.; Hantman, A. W.; Harris, K. D.; Lee, A. K.; Moser, E. I.; O'Keefe, J.; Renart, A.; Svoboda, K.; Häusser, M.; Haesler, S.; Carandini, M.; Harris, T. D.
10.1101/2020.10.27.358291 — neuroscience — Posted on 2020-10-28
546 Validity of the Lumen(R) hand-held metabolic device to measure fuel utilization in healthy young adults
Lorenz, K. A.; Yeshurun, S.; Aziz, R.; Ortiz-Delatorre, J.; Bagley, J. R.; Mor, M.; Kern, M.
10.1101/2020.05.05.078980 — physiology — Posted on 2020-10-28
552 Genetic influences on cell type specific gene expression and splicing during neurogenesis elucidate regulatory mechanisms of brain traits
Aygün, N.; Elwell, A. L.; Liang, D.; Lafferty, M. J.; Cheek, K. E.; Courtney, K. P.; Mory, J.; Hadden-Ford, E.; Krupa, O.; de la Torre-Ubieta, L.; Geschwind, D. H.; Love, M. I.; Stein, J. L.
10.1101/2020.10.21.349019 — genetics — Posted on 2020-10-28
554 Cytoplasm Biophysical Properties Madolute Microtubule Dynamics
Molines, A. T.; Lemiere, J.; Edrington, C. H.; Hsu, C.-T.; Steinmark, I. E.; Suhling, K.; Goshima, G.; Holt, L. J.; Brouhard, G.; Chang, F. T.
10.1101/2020.10.27.352716 — cell biology — Posted on 2020-10-28
555 The non-coding RNA miR-17~92 is a central mediator of T cell activation
Doelz, M.; Gagnon, J. D.; Kornete, M.; Marone, R.; Bantug, G.; Kageyama, R.; Hess, C.; Ansel, K. M.; Seyres, D.; Roux, J.; Jeker, L. T.
10.1101/2020.10.13.336537 — immunology — Posted on 2020-10-28
557 Parallel organization of cerebellar pathways to sensorimotor, associative, and modulatory forebrain
Pisano, T. J.; Dhanerawala, Z. M.; Kislin, M.; Bakshinskaya, D.; Engel, E. A.; Lee, J.; de Oude, N. L.; Umadevi Venkataraju, K.; Verpeut, J. L.; Boele, H.-J.; Wang, S. S.- H.
10.1101/2020.03.06.979153 — neuroscience — Posted on 2020-10-28
562 PieParty: Visualizing cells from scRNA-seq data as pie charts
Kurtenbach, S.; Dollar, J. J.; Cruz, A. M.; Durante, M. A.; Harbour, J. W.
10.1101/2020.08.25.267021 — bioinformatics — Posted on 2020-10-28
563 Single cell transcriptome analysis defines heterogeneity of the adult murine pancreatic ductal tree
Hendley, A. M.; Rao, A. A.; Leonhardt, L.; Ashe, S.; Smith, J. A.; Giacometti, S.; Peng, X. L.; Jiang, H.; Berrios, D.; Pawlak, M.; Li, L. Y.; Lee, J.; Collisson, E. A.; Anderson, M.; Fragiadakis, G. K.; Yeh, J. J.; Chun, J. Y.; Kim, G. E.; Weaver, V. M.; Hebrok, M.
10.1101/2020.10.12.336784 — bioinformatics — Posted on 2020-10-28
565 Identification and Characterization of a B-Raf Kinase Alpha Helix Critical for the Activity of MEK Kinase in MAPK Signaling
Nguyen, D.; Lin, L. Y.; Zhou, J.; Kibby, E.; Sia, T.; Tillis, T.; Vapuryan, N.; Xu, M.-R.; Potluri, R.; Shin, Y.; Erler, E.; Bronkema, N.; Boehmler, D.; Chung, C.; Burkhard, C.; Zeng, S. H.; Grasso, M.; Acevedo, L. A.; Marmorstein, R.; Fera, D.
10.1101/2020.07.19.211177 — biochemistry — Posted on 2020-10-28
568 Ancestry adjustment improves genome-wide estimates of regional intolerance
Hayeck, T. J.; Stong, N.; Baugh, E.; Dhindsa, R.; Turner, T. N.; Malakar, A.; Duan, Y.; Ionita-Laza, I.; Goldstein, D.; Andrew Allen, A. S.; Mosbruger, T. L.
10.1101/2020.03.05.979203 — genetics — Posted on 2020-10-28
570 A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells
Guo, Q.; Kim, A. D.; Li, B.; Ransick, A.; Bugacov, H.; Chen, X.; Lindstrom, N. O.; Brown, A.; Oxburgh, L.; Ren, B.; McMahon, A. P.
10.1101/2020.10.26.356410 — developmental biology — Posted on 2020-10-28
571 Specific OCRL1 patient mutations differentially impact Lowe Syndrome cellular phenotypes
Ramadesikan, S.; Skiba, L.; Lee, J.; Madhivanan, K.; Sarkar, D.; De La Fuente, A.; Hanna, C. B.; Hazbun, T.; Kihara, D.; Aguilar, R. C.
10.1101/2020.08.04.236612 — cell biology — Posted on 2020-10-28
572 Method comparison studies of telomere length measurement using qPCR approaches: a critical appraisal of the literature
Lindrose, A. R.; McLester-Davis, L. W. Y.; Tristano, R. I.; Kataria, L.; Gadalla, S. M.; Eisenberg, D. T. A.; Verhulst, S.; Drury, S.
10.1101/2020.09.04.282632 — molecular biology — Posted on 2020-10-27
573 Multi-omic Single-cell Atlas Reveals Broad Ex Vivo Effects on Human Immunobiology
Savage, A. K.; Gutschow, M. V.; Chiang, T.; Henderson, K.; Green, R.; Chaudhari, M.; Swanson, E.; Heubeck, A. T.; Kondza, N.; Burley, K. C.; Genge, P. C.; Lord, C.; Smith, T.; Beaubien, A.; Goldy, J.; Bolouri, H.; Buckner, J. H.; Meijer, P.; Coffey, E. M.; Li, X.-j.; Skene, P. J.; Torgerson, T. R.; Bumol, T. F.
10.1101/2020.10.18.344663 — immunology — Posted on 2020-10-28
574 Eating to dare - Nutrition impacts human risky decision and related brain function
Liu, L.; Artigas, S. O.; Ulrich, A.; Tardu, J.; Mohr, P. N. C.; Wilms, B.; Koletzko, B.; Schmid, S. M.; Park, S. Q.
10.1101/2020.05.10.085688 — neuroscience — Posted on 2020-10-27
576 Auditory Decisions in the Supplementary Motor Area
Moran, I.; Perez-Orive, J.; Melchor, J.; Figueroa, T.; Lemus, L.
10.1101/2020.10.20.347864 — neuroscience — Posted on 2020-10-27
580 Chronic Perinatal Hypoxia Delays Cardiac Maturation in a Mouse Model for Cyanotic Congenital Heart Disease
Romanowicz, J.; Dhari, Z.; Guerrelli, D.; Mulvany, C.; Reilly, M.; Swift, L.; Vasandani, N.; Ramadan, M.; Ishibashi, N.; Posnack, N.
10.1101/2020.05.28.117648 — physiology — Posted on 2020-10-27
581 S-nitrosoglutathione reductase deficiency causes aberrant placental S-nitrosylation and preeclampsia.
Kulandavelu, S.; Dulce, R. A.; Murray, C. I.; Bellio, M. A.; Fritsch, J.; Kanashiro-Takeuchi, R.; Arora, H.; Paulino, E.; Soetkamp, D.; Balkan, W.; Van Eyk, J. E.; Hare, J. M.
10.1101/2020.07.01.183012 — physiology — Posted on 2020-10-27
583 PKD promotes activity-dependent AMPA receptorendocytosis in hippocampal neurons
Oueslati Morales, C. O.; Ignacz, A.; Bencsik, N.; Ratkai, A. E.; Lieb, W. S.; Eisler, S. A.; Szucs, A.; Schlett, K.; Hausser, A.
10.1101/2020.04.09.033514 — neuroscience — Posted on 2020-10-27
588 Light intensity affects the coloration and structure of chimeric leaves of Ananas comosus var. bracteatus
Yang, W.; Lin, Y.; Xue, Y.; Mao, M.; Zhou, X.; Hu, H.; Liu, J.; Feng, L.; Zhang, H.; Luo, J.; Ma, J.
10.1101/2020.10.27.356857 — physiology — Posted on 2020-10-27
590 Re-discovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis
Wang, H.; Xu, M.; Engelhart, C. A.; Zhang, X.; Yan, B.; Pan, M.; Xu, Y.; Fan, S.; Liu, R.; Xu, L.; Hua, L.; Schnappinger, D.; Chen, S.
10.1101/2020.10.27.357681 — biochemistry — Posted on 2020-10-27
591 A booster dose enhances immunogenicity of the COVID-19 vaccine candidate ChAdOx1 nCoV-19 in aged mice
Silva-Cayetano, A.; Foster, W. S.; Innocentin, S.; Belij-Rammerstorfer, S.; Spencer, A. J.; Burton, O. T.; Fra-Bido, S.; Lee, J. L.; Thakur, N.; Conceicao, C.; Wright, D.; Barrett, J.; Evans-Bailey, N.; Noble, C.; Bailey, D.; Liston, A.; Gilbert, S. C.; Lambe, T.; Linterman, M. A.
10.1101/2020.10.27.357426 — immunology — Posted on 2020-10-27
593 Activating mGlu3 metabotropic glutamate receptors rescues schizophrenia-like cognitive deficits through metaplastic adaptations within the hippocampus.
Dogra, S.; Stansley, B. J.; Xiang, Z.; Qian, W.; Gogliotti, R. G.; Nicoletti, F.; Lindsley, C. W.; Niswender, C. M.; Joffe, M. E.; Conn, P. J.
10.1101/2020.10.27.356196 — pharmacology and toxicology — Posted on 2020-10-27
595 Negative durotaxis: cell movement toward softer environments
Isomursu, A.; Park, K.-Y.; Hou, J.; Bo, C.; Shamsan, G.; Fuller, B.; Kasim, J.; Mahmoodi, M. M.; Lu, T. J.; Genin, G. M.; Xu, F.; Lin, M.; Distefano, M.; Ivaska, J.; Odde, D. J.
10.1101/2020.10.27.357178 — biophysics — Posted on 2020-10-27
597 A robust sequencing assay of a thousand amplicons for the high-throughput population monitoring of Alpine ibex immunogenetics
Kessler, C.; Brambilla, A.; Waldvogel, D.; Camenisch, G.; Biebach, I.; Leigh, D. M.; Grossen, C.; Croll, D.
10.1101/2020.10.27.357194 — genomics — Posted on 2020-10-27
600 New Genes in Drosophila Quickly Evolved Essential Functions in Viability During Development
Xia, S.; VanKuren, N. W.; Chen, C.; Zhang, L.; Kemkemer, C.; Shao, Y.; Jia, H.; Lee, U.; Advani, A. S.; Gschwend, A.; Vibranovski, M.; Chen, S.; Zhang, Y. E.; Long, M.
10.1101/2020.10.27.357848 — developmental biology — Posted on 2020-10-27
601 AKAP350 REGULATES CYTOSKELETON REMODELLING AND LFA-1 ORGANIZATION DURING NK CYTOLYTIC RESPONSE
Pariani, A. P.; Almada, E.; Hidalgo, F.; Borini-Etichetti, C.; Vena, R.; Favre, C.; Goldenring, J. R.; Larocca, M. C.
10.1101/2020.10.27.357970 — cell biology — Posted on 2020-10-27
602 Differentiation of Human induced Pluripotent Stem Cells to Authentic Macrophages using Fully Defined, Serum Free, Open Source Media
Vaughan-Jackson, A.; Stodolak, S.; Ebrahimi, K. H.; Browne, C.; Reardon, P. K.; Pires, E.; Gilbert-Jaramillo, J.; Cowley, S. A.; James, W. S.
10.1101/2020.10.27.357632 — immunology — Posted on 2020-10-27
603 Transcriptome and Chromatin Landscape of iNKT cells are Shaped by Subset Differentiation and Antigen Exposure
Murray, M. P.; Engel, I.; Seumois, G.; de la Mata, S. H.; Rosales, S. L.; Sethi, A.; Premlal, A. L. R.; Seo, G.-Y.; Greenbaum, J.; Vijayanand, P.; Scott-Browne, J. P.; Kronenberg, M.
10.1101/2020.10.27.357673 — immunology — Posted on 2020-10-27
607 Genetic determinants of COVID-19 drug efficacy revealed by genome-wide CRISPR screens
Jiang, W.; Yang, A.; Ma, J.; Lv, D.; Liu, M.; Xu, L.; Wang, C.; He, Z.; Chen, S.; Zhao, J.; Chen, S.; Jiang, Q.; Chu, Y.; Shan, L.; Zhou, Z.; Zhao, Y.; Long, G.; Jiang, H.
10.1101/2020.10.26.356279 — pharmacology and toxicology — Posted on 2020-10-27
608 Pancreatic Ductal Adenocarcinoma Comprises Coexisting Regulatory States with both Common and Distinct Dependencies
Laise, P.; Turunen, M.; Maurer, C.; Curiel, A.; Elyada, E.; Schmierer, B.; Tomassoni, L.; Worley, J.; Alvarez, M. J.; Kesner, J.; Tan, X.; Tagore, S.; Wang, A. L. E.; Ge, S.; Iuga, A. C.; Griffin, A.; Wong, W.; Manji, G.; Notta, F.; Tuveson, D.; Olive, K. P.; Califano, A.
10.1101/2020.10.27.357269 — cancer biology — Posted on 2020-10-27
609 Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia
Wang, F.; Morita, K.; DiNardo, C.; Furudate, K.; Tanaka, T.; Yan, Y.; Patel, K.; MacBeth, K.; Wu, B.; Liu, G.; Frattini, M.; Matthews, J.; Little, L.; Gumbs, C.; Song, X.; Zhang, J.; Thompson, E.; Kadia, T.; Garcia-Manero, G.; Jabbour, E.; Ravandi, F.; Bhalla, K.; Konopleva, M.; Kantarjian, H.; Futreal, A.; Takahashi, K.
10.1101/2020.10.27.357111 — cancer biology — Posted on 2020-10-27
613 Cell size is a determinant of stem cell potential during aging
Lengefeld, J.; Cheng, C.-W.; Maretich, P.; McReynolds, M. R.; Blair, M.; Hagen, H.; Sullivan, E. J.; Majors, K.; Roberts, C.; Kang, J. H.; Steiner, J.; Miettinen, T. P.; Manalis, S.; Antebi, A.; Lees, J.; Boyer, L.; Yilmaz, O. H.; Amon, A.
10.1101/2020.10.27.355388 — cell biology — Posted on 2020-10-27
615 SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility
Zhou, B.; Thao, T. T. N.; Hoffmann, D.; Taddeo, A.; Ebert, N.; Labroussaa, F.; Pohlmann, A.; King, J.; Portmann, J.; Halwe, N. J.; Ulrich, L.; Trueb, B. S.; Kelly, J. N.; Fan, X.; Hoffmann, B.; Steiner, S.; Wang, L.; Thomann, L.; Lin, X.; Stalder, H.; Pozzi, B.; de Brot, S.; Jiang, N.; Cui, D.; Hossain, J.; Wilson, M.; Keller, M. W.; Stark, T. J.; Barnes, J. R.; Dijkman, R.; Jores, J.; Benarafa, C.; Wentworth, D. E.; Thiel, V.; Beer, M.
10.1101/2020.10.27.357558 — microbiology — Posted on 2020-10-27
616 SARS-CoV-2 viroporin triggers the NLRP3 inflammatory pathway
Xu, H.; Chitre, S. A.; Akinyemi, I. A.; Loeb, J. C.; Lednicky, J. A.; McIntosh, M. T.; Bhaduri-McIntosh, S.
10.1101/2020.10.27.357731 — microbiology — Posted on 2020-10-27
619 ISG15-dependent Activation of the RNA Sensor MDA5 and its Antagonism by the SARS-CoV-2 papain-like protease
Liu, G.; Lee, J.-H.; Parker, Z. M.; Acharya, D.; Chiang, J. J.; van Gent, M.; Riedl, W.; Davis-Gardner, M. E.; Wies, E.; Chiang, C.; Gack, M. U.
10.1101/2020.10.26.356048 — immunology — Posted on 2020-10-27
620 The Endothelin Receptor Antagonist Macitentan Ameliorates Endothelin-Mediated Vasoconstriction and Promotes Neuroprotection of Retinal Ganglion Cells in Rats
Stankowska, D. L.; Zhang, W.; He, S.; Krishnamoorthy, V. R.; Harris, P.; Hall, T.; Chaphalkar, R. M.; Kodati, B.; Chavala, S. H.; Krishnamoorthy, R. R.
10.1101/2020.10.27.357814 — neuroscience — Posted on 2020-10-27
621 Remdesivir Metabolite GS-441524 Efficiently Inhibits SARS-CoV-2 Infection in Mouse Model
Li, Y.; Cao, L.; Li, G.; Cong, F.; Li, Y.; Sun, J.; Luo, Y.; Chen, G.; Li, G.; Wang, P.; Xing, F.; Ji, Y.; Zhao, J.; Zhang, Y.; Guo, D.; Zhang, X.
10.1101/2020.10.26.353300 — pharmacology and toxicology — Posted on 2020-10-27
626 Homeodomain protein 1 is an essential regulator of gene expression during sexual differentiation of malaria parasites
Campelo Morillo, R.; Tong, X.; Xie, W.; Lenz, T.; Batugedara, G.; Tabassum, N.; Orchard, L. M.; Daher, W.; Patel, D.; Noble, W. S.; Llinas, M.; Le Roch, K. G.; Kafsack, B. F. C.
10.1101/2020.10.26.352583 — microbiology — Posted on 2020-10-27
627 Dense movement with embedded sparse action-type representations in the output layer of motor cortex
Currie, S. P.; Ammer, J.; Premchand, B.; Wu, Y.; Eleftheriou, C.; Faisal, A. A.; Hennig, M. H.; Duguid, I.
10.1101/2020.10.27.357087 — neuroscience — Posted on 2020-10-27
628 Bayes Estimate of Primary Threshold in Cluster-wise fMRI Inferences
Ge, Y.; Hare, S.; Chen, G.; Waltz, J.; Kochunov, P.; Hong, E.; Chen, S.
10.1101/2020.10.03.324962 — neuroscience — Posted on 2020-10-27
629 Race specific differences in DNA damage repair dysregulation in breast cancer and association with outcome
Mazumder, A.; Jimenez, A.; Ellsworth, R.; Freedland, S.; George, S.; Bainbridge, M.; Haricharan, S.
10.1101/2020.10.26.356006 — cancer biology — Posted on 2020-10-27
630 Fast volumetric mapping of human brain slices
Pesce, L.; Laurino, A.; Gavryusev, V.; Mazzamuto, G.; Sancataldo, G.; Scardigli, M.; Roffilli, M.; Silvestri, L.; Costantini, I.; Pavone, F. S.
10.1101/2020.10.27.357186 — biophysics — Posted on 2020-10-27
631 The genomic epidemiology of SARS-CoV-2 in Palestine
Qutob, N.; Salah, Z.; Richard, D.; Darwish, H.; Sallam, H.; Shtayeh, I.; Najjar, O.; Balloux, F.; van Dorp, L.
10.1101/2020.10.26.355677 — genomics — Posted on 2020-10-27
632 Congenital Zika Syndrome is associated with interferon alfa receptor 1
Azamor, T.; Cunha, D. P.; da Silva, A. M. V.; Bezerra, O. C. d. L.; Ribeiro-Alves, M.; Calvo, T. L.; Kehdy, F. d. S. G.; Manta, F. S. d. N.; Pinto, T. G.; Ferreira, L. P.; Portari, E. A.; Guida, L. d. C.; Gomes, L.; Moreira, M. E. L.; de Carvalho, E. F.; Cardoso, C. C.; Muller, M.; Ano Bom, A. P. D.; Neves, P. C. d. C.; Vasconcelos, Z.; Moraes, M. O.
10.1101/715862 — genetics — Posted on 2020-10-27
634 Chimeric single α-helical domains as rigid fusion protein connections for protein nanotechnology and structural biology
Collu, G.; Bierig, T.; Krebs, A.-S.; Engilberge, S.; Varma, N.; Guixa-Gonzalez, R.; Deupi, X.; Olieric, V.; Poghosyan, E.; Benoit, R. M.
10.1101/2020.09.29.318410 — molecular biology — Posted on 2020-10-27
637 DAGBagM: Learning directed acyclic graphs of mixed variables with an application to identify prognostic protein biomarkers in ovarian cancer
Chowdhury, S.; Wang, R.; Yu, Q.; Huntoon, C. J.; Karnitz, L. M.; Kaufmann, S. H.; Gygi, S. P.; Birrer, M. J.; Paulovich, A. G.; Peng, J.; Wang, P.
10.1101/2020.10.26.349076 — systems biology — Posted on 2020-10-27
638 ChronoRoot: High-throughput phenotyping by deep segmentation networks reveals novel temporal parameters of plant root system architecture
Gaggion, N.; Ariel, F.; Daric, V.; Lambert, E.; Legendre, S.; Roule, T.; Camoirano, A.; Milone, D. H.; Crespi, M.; Blein, T.; Ferrante, E.
10.1101/2020.10.27.350553 — plant biology — Posted on 2020-10-27
641 Experimental and mathematical modelling of magnetically labelled mesenchymal stromal cell delivery
Yeo, E. F.; Markides, H.; Shade, A. T.; Studd, A. J.; Oliver, J. M.; Waters, S. L.; El Haj, A. J.
10.1101/2020.10.27.356725 — bioengineering — Posted on 2020-10-27
647 Clonal propagation history shapes the intra-cultivar genetic diversity in Malbec grapevines
Calderon, L.; Mauri, N.; Munoz, C.; Carbonell-Bejerano, P.; Bree, L.; Sola, C.; Gomez-Talquenca, S.; Royo, C.; Ibanez, J.; Martinez-Zapater, J. M.; Lijavetzky, D.
10.1101/2020.10.27.356790 — genomics — Posted on 2020-10-27
648 NETMAGE: a humaN-disEase phenoType MAp GEnerator for the Visualization of PheWAS
Sriram, V.; Shivakumar, M.; Jung, S.-H.; Bang, L.; Verma, A.; Lee, S.; Choe, E. K.; Kim, D.
10.1101/2020.10.27.357103 — genetics — Posted on 2020-10-27
649 Gamete simulation improves polygenic transmission disequilibrium analysis
Chen, J.; You, J.; Zhao, Z.; Ni, Z.; Huang, K.; Wu, Y.; Fletcher, J.; Lu, Q.
10.1101/2020.10.26.355602 — genetics — Posted on 2020-10-27
650 Root water gates and not changes in root structure provide new insights into plant physiological responses and adaptations to drought, flooding and salinity
Domec, J.-C.; King, J. S.; Carmichael, M. J.; Treado Overby, A.; Wortemann, R.; Smith, W. K.; Miao, G.; Noormets, A.; Johnson, D. M.
10.1101/2020.10.27.357251 — developmental biology — Posted on 2020-10-27
651 TaqMan Array Cards enable monitoring of diverse enteric pathogens across environmental and host reservoirs
Lappan, R.; Henry, R.; Chown, S. L.; Luby, S. P.; Higginson, E.; Bata, L.; Jirapanjawat, T.; Schang, C.; Openshaw, J. J.; O'Toole, J.; Lin, A.; Tela, A.; Wong, T. H. F.; French, M. A.; Brown, R. R.; Leder, K.; Greening, C.; McCarthy, D.
10.1101/2020.10.27.356642 — microbiology — Posted on 2020-10-27
652 Retinoic acid Inducible Gene-I like Receptors Activate Snail and Slug to Limit RNA Viral Infections
Vedagiri, D.; Gupta, D.; Mishra, A.; Krishna, G.; Bhaskar, M.; Basu, A.; Nayak, D.; Kalia, M.; Valiya, M. V.; Harshan, K. H.
10.1101/2020.10.27.357509 — immunology — Posted on 2020-10-27
654 Identifying the functions of two biomarkers in human oligodendrocyte progenitor cell development
Zhou, H.; He, Y.; Yang, Y.; Wang, Z.; Wang, Q.; Hu, C.; Wang, X.; Lu, S.; Li, K.; Luan, Z.
10.1101/2020.10.27.357244 — neuroscience — Posted on 2020-10-27
658 Sex-specific classification of drug-induced Torsade de Pointes susceptibility using cardiac simulations and machine learning
Fogli Iseppe, A.; Ni, H.; Zhu, S.; Zhang, X.; Coppini, R.; Yang, P.-C.; Srivatsa, U.; Clancy, C. E.; Edwards, A. G.; Morotti, S.; Grandi, E.
10.1101/2020.10.26.352740 — pharmacology and toxicology — Posted on 2020-10-27
659 BrainGENIE: The Brain Gene Expression and Network Imputation Engine
Hess, J. L.; Chen, S.; Quinn, T. P.; Neuropsychiatric Consortium for Analysis and Sharing of Transcriptomes, ; Kong, S. W.; Cairns, M.; Tsuang, M.; Faraone, S. V.; Glatt, S. J.
10.1101/2020.10.27.356766 — bioinformatics — Posted on 2020-10-27
660 Applications of machine learning to solve genetics problems
Sowunmi, K.; Soyebo, T. A.; Okosesi, E. A.; Adesiyan, A. L.; Oladimeji, K. A.; Ajibola, O. A.; Ogunlana, Y. O.; Agboola, O. W.; Kaur, G.; Atoromola, H.; Oladipupo, T. A.
10.1101/2020.10.27.354092 — bioinformatics — Posted on 2020-10-27
664 Genomic structural variation in Nebbiolo grapevines at the individual, clonal and cultivar levels
Maestri, S.; Gambino, G.; Minio, A.; Perrone, I.; Cosentino, E.; Giovannone, B.; Lopatriello, G.; Marcolungo, L.; Cantu, D.; Rossato, M.; Delledonne, M.; Calderon, L.
10.1101/2020.10.27.357046 — genomics — Posted on 2020-10-27
665 Poxviruses capture host genes by LINE-1 retrotransposition
Fixsen, S. M.; Cone, K. R.; Goldstein, S. A.; Sasani, T. A.; Quinlan, A. R.; Rothenburg, S.; Elde, N. C.
10.1101/2020.10.26.356402 — evolutionary biology — Posted on 2020-10-27
666 Hidden genetic variation in plasticity increases the potential to adapt to novel environments
Walter, G. M.; Clark, J.; Terranova, D.; Cozzolino, S.; Cristaudo, A.; Hiscock, S. J.; Bridle, J. R.
10.1101/2020.10.26.356451 — evolutionary biology — Posted on 2020-10-27
667 Assessing short- and long-term variations in diversity, timing, and body condition of migratory frugivorous birds
Campo-Celada, M.; Mendoza, I.; Benitez-Lopez, A.; Gutierrez-Exposito, C.; Rabadan-Gonzalez, J.; Jordano, P.
10.1101/2020.10.27.356709 — ecology — Posted on 2020-10-27
668 Annual phytoplankton dynamics in coastal waters from Fildes Bay, Western Antarctic Peninsula.
Trefaut, N.; De la Iglesia, R.; Moreno-Pino, M.; Lopes dos Santos, A.; Gerikas Ribeiro, C.; Cristi, A.; Marie, D.; Vaulot, D.
10.1101/2020.10.27.356600 — ecology — Posted on 2020-10-27
669 Specificities of exosome versus small ectosome secretion revealed by live intracellulartracking and synchronized extracellular vesicle release of CD9 and CD63
Mathieu, M.; Nevo, N.; Jouve, M.; Valenzuela, J.-I.; Maurin, M.; Verweij, F.; Palmulli, R.; Lankar, D.; Dingli, F.; Loew, D.; Rubinstein, E.; Boncompain, G.; Perez, F.; Thery, C.
10.1101/2020.10.27.323766 — cell biology — Posted on 2020-10-27
672 RL-118 and 11β-HSD1 target engagement through TAPS assay: behaviour and molecular analysis
Puigoriol-Illamola, D.; Companys-Alemany, J.; McGuire, K.; Homer, N.; Leiva, R.; Vazquez, S.; Mole, D. J.; Grinan-Ferre, C.; Pallas, M.
10.1101/2020.10.27.356881 — molecular biology — Posted on 2020-10-27
673 Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase
Xia, Z.; Tang, M.; Zhang, H.; Gimple, R.; Prager, B.; Tang, H.; Sun, C.; Liu, F.; Lin, P.; Mei, Y.; Du, R.; Rich, J.; Xie, Q.
10.1101/2020.10.27.356436 — molecular biology — Posted on 2020-10-27
675 High-resolution genomic comparisons within Salmonella enterica serotypes derived from beef feedlot cattle: parsing the roles of cattle source, pen, animal, sample type and production period
Levent, G.; Schlochtermeier, A.; Ives, S. E.; Norman, K. N.; Lawhon, S. D.; Loneragan, G. H.; Anderson, R.; Vinasco, J.; den Bakker, H. C.; Scott, H. M.
10.1101/2020.10.26.356493 — microbiology — Posted on 2020-10-27
677 The Regulatory Evolution of the Primate Fine-Motor System
Wirthlin, M. E.; Kaplow, I. M.; Lawler, A. J.; He, J.; Phan, B. N.; Brown, A. R.; Stauffer, W. R.; Pfenning, A. R.
10.1101/2020.10.27.356733 — neuroscience — Posted on 2020-10-27
681 Resveratrol reduces COMPopathy in mice through activation of autophagy
Hecht, J. T.; Coustry, F.; Veerisetty, A.; Hossain, M. G.; Posey, K.
10.1101/2020.10.26.355628 — pathology — Posted on 2020-10-27
683 Deep-learning based denoising and reconstruction of super-resolution structured illumination microscopy images
Shah, Z. H.; Müller, M.; Wang, T.-C.; Scheidig, P. M.; Schneider, A.; Schüttpelz, M.; Huser, T.; Schenck, W.
10.1101/2020.10.27.352633 — biophysics — Posted on 2020-10-27
684 DNA-loop extruding SMC complexes can traverse one another in vivo
Brandão, H. B.; Ren, Z.; Karaboja, X.; Mirny, L. A.; Wang, X.
10.1101/2020.10.26.356329 — biophysics — Posted on 2020-10-27
691 A new twist of rubredoxin function in M. tuberculosis
Sushko, T.; Kavaleuski, A.; Grabovec, I.; Kavaleuskaya, A.; Vakhrameev, D.; Bukhdruker, S.; Marin, E.; Kuzikov, A.; Masamrekh, R.; Shumyantseva, V.; Tsumoto, K.; Borshchevskiy, V.; Gilep, A.; Strushkevich, N.
10.1101/2020.10.27.356691 — biochemistry — Posted on 2020-10-27
692 Associations between childhood family emotional health, fronto-limbic grey matter volume, and saliva 5mC in young adulthood
Pfeiffer, J.; Bustamante, A. C.; Kim, G. S.; Armstrong, D.; Knodt, A. R.; Koenen, K. C.; Hariri, A. R.; Uddin, M.
10.1101/2020.10.26.355347 — genomics — Posted on 2020-10-27
693 RNA polymerase II is required for spatial chromatin reorganization following exit from mitosis
Zhang, S.; Uebelmesser, N.; Josipovic, N.; Forte, G.; Slotman, J. A.; Chiang, M.; Gothe, H.; Gusmao, E. G.; Becker, C.; Altmueller, J.; Houtsmuller, A. B.; Roukos, V.; Wendt, K. S.; Marenduzzo, D.; Papantonis, A.
10.1101/2020.10.27.356915 — genomics — Posted on 2020-10-27
695 A curated dataset of modern and ancient high-coverage shotgun human genomes.
Maisano Delser, P.; Jones, E. R.; Hovhannisyan, A.; Cassidy, L.; Pinhasi, R.; Manica, A.
10.1101/2020.10.27.351692 — genomics — Posted on 2020-10-27
696 Somatic CAG expansion in Huntington's disease is dependent on the MLH3 endonuclease domain, which can be excluded via MLH3 splice redirection to suppress expansion
Roy, J. C. L.; Vitalo, A.; Andrew, M. A.; Mota-Silva, E.; Kovalenko, M.; Burch, Z.; Nhu, A. M.; Cohen, P. E.; Grabczyk, E.; Wheeler, V. C.; Mouro Pinto, R.
10.1101/2020.10.26.356238 — genetics — Posted on 2020-10-27
698 TGS1 controls snRNA 3' end processing, prevents neurodegeneration and ameliorates SMN-dependent neurological phenotypes in vivo
Chen, L.; Roake, C. M.; Maccallini, P.; Bavasso, F.; Dehghannasiri, R.; Santonicola, P.; Mendoza-Ferreira, N.; Scatolini, L.; Rizzuti, L.; Esposito, A.; Gallotta, I.; Francia, S.; Cacchione, S.; Hammerschmidt, M.; De Pitta, C.; Sales, G.; Salzman, J.; Pellizzoni, L.; Wirth, B.; Di Schiavi, E.; Gatti, M.; Artandi, S. E.; Raffa, G. D.
10.1101/2020.10.27.356782 — genetics — Posted on 2020-10-27
699 A skyline birth-death process for inferring the population size from a reconstructed tree with occurrences
Andreoletti, J.; Zwaans, A.; Warnock, R. C.; Aguirre-Fernandez, G.; Barido-Sottani, J.; Gupta, A.; Stadler, T.; Manceau, M.
10.1101/2020.10.27.356758 — evolutionary biology — Posted on 2020-10-27
702 Physiological and ecological warnings that Dodder pose an exigent threat to farmlands in Eastern Africa
Masanga, J.; Mwangi, B. N.; Kibet, W.; Wamalwa, M.; Sagero, P.; Oduor, R.; Ngugi, M.; Alakonya, A.; Ojola, P.; Bellis, E.; Runo, S.
10.1101/2020.10.26.355883 — ecology — Posted on 2020-10-27
705 High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility
Goetschius, D. J.; Hartmann, S. R.; Subramanian, S.; Bator, C. M.; Christensen, N. D.; Hafenstein, S. L.
10.1101/2020.10.27.357004 — microbiology — Posted on 2020-10-27
707 Blood gene expression-based prediction of lethality after respiratory infection by influenza A virus in mice
Milanez-Almeida, P.; Martins, A. J.; Torabi-Parizi, P.; Franco, L. M.; Tsang, J. S.; Germain, R. N.
10.1101/2020.10.27.357053 — immunology — Posted on 2020-10-27
708 Timing variability and midfrontal ~4 Hz rhythms correlate with cognition in Parkinson's disease
Singh, A.; Cole, R.; Espinoza, A. I.; Evans, A.; Cao, S.; Cavanagh, J. F.; Narayanan, N. S.
10.1101/2020.10.26.356154 — neuroscience — Posted on 2020-10-27
709 The association between pain-induced autonomic reactivity and descending pain control is mediated by the periaqueductal grey
Makovac, E.; Venezia, A.; Hohenschurz-Schmidt, D.; Dipasquale, O.; Jackson, J. B.; Medina, S.; O'Daly, O.; Williams, S. C.; McMahon, S. B.; Howard, M. A.
10.1101/2020.10.26.355529 — neuroscience — Posted on 2020-10-27
711 A configurable model of the synaptic proteome reveals the molecular mechanisms of disease co-morbidity.
Sorokina, O.; McLean, C.; Croning, M. D.; Heil, K. F.; Wysochka, E.; He, X.; Sterratt, D. C.; Grant, S.; Simpson, I.; Armstrong, J. D.
10.1101/2020.10.27.356899 — systems biology — Posted on 2020-10-27
712 LACCASE is Necessary for Root Development in Salvia miltiorrhiza
Zhou, Z.; Li, Q.; Wang, Y.; Xiao, L.; Bu, Q.; Hao, K.; Guo, M.; Chen, W.; Zhang, L.
10.1101/2020.10.26.356097 — plant biology — Posted on 2020-10-27
713 Meta-Analysis Identifies Pleiotropic Loci Controlling Phenotypic Trade-offs in Sorghum
Mural, R. V.; Grzybowski, M.; Miao, C.; Damke, A.; Sapkota, S.; Boyles, R. E.; Salas Fernandez, M. G.; Schnable, P. S.; Sigmon, B.; Kresovich, S.; Schnable, J. C.
10.1101/2020.10.27.355495 — plant biology — Posted on 2020-10-27
714 Refining physico-chemical rules for herbicides using an antimalarial library
Sukhoverkov, K. V.; Corral, M. G.; Leroux, J.; Haywood, J. S.; Johnen, P.; Newton, T.; Stubbs, K. A.; Mylne, J. S.
10.1101/2020.10.27.356576 — plant biology — Posted on 2020-10-27
717 A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA targets sites promotes commitment of mammalian nephron progenitor cells
Guo, Q.; Kim, A. D.; Li, B.; Ransick, A.; Bugacov, H.; Chen, X.; Lindstrom, N. O.; Brown, A.; Oxburgh, L.; Ren, B.; McMahon, A. P.
10.1101/2020.10.26.356410 — developmental biology — Posted on 2020-10-27
718 Large-scale characterization of sex pheromone communication systems in Drosophila
Khallaf, M. A.; Cui, R.; Weissflog, J.; Svatos, A.; Dweck, H. K. M.; Valenzano, D. R.; Hansson, B. S.; Knaden, M.
10.1101/2020.09.21.305854 — neuroscience — Posted on 2020-10-27
724 Methyl-CpG binding domain 2 (Mbd2) is an Epigenetic Regulator of Autism-Risk Genes and Cognition
Lax, E.; Do Carmo, S.; Enuka, Y.; Sapozhnikov, D. M.; Welikovitch, L. A.; Mahmood, N.; Rabbani, S. A.; Wang, L.; Hancock, W. W.; Yarden, Y.; Szyf, M.
10.1101/247197 — neuroscience — Posted on 2020-10-27
727 Local calcium signals in pacemaker cells heart rate and body mass are self-similar from mice to humans
Tagirova (Sirenko), S.; Tsutsui, K.; Yang, D.; Ziman, B. D.; Tarasov, K. V.; Yaniv, Y.; Lakatta, E. G.
10.1101/2020.10.26.355412 — physiology — Posted on 2020-10-27
728 Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR mutant lung cancer
Nanjo, S.; Wu, W.; Karachaliou, N.; Blakely, C.; Suzuki, J.; Ali, S.; Kerr, L.; Olivas, V.; Shue, J.; Rotow, J.; Mayekar, M.; Haderk, F.; Chatterjee, N.; Urisman, A.; Kirichok, Y.; Tan, D.; Rosell, R.; Okimoto, R.; Bivona, T.
10.1101/2020.10.26.356352 — cancer biology — Posted on 2020-10-27
732 The RNA Structurome in the Asexual Blood Stages of Malaria Pathogen Plasmodium falciparum
Alvarez, D. R. A.; Ospina, A.; Dey, A.; Barwell, T.; Zheng, B.; Li, C.; Basu, S.; Shi, X.; Kadri, S.; Chakrabarti, K.
10.1101/2020.10.25.354316 — molecular biology — Posted on 2020-10-27
733 Emergence and evolution of antimicrobial resistance genes and mutations in Neisseria gonorrhoeae
Yahara, K.; Ma, K. C.; Mortimer, T. D.; Shimuta, K.; Nakayama, S.-i.; Hirabayashi, A.; Suzuki, M.; Jinnai, M.; Ohya, H.; Kuroki, T.; Watanabe, Y.; Yasuda, M.; Deguchi, T.; Eldholm, V.; Harrison, O. B.; Maiden, M. C. J.; Grad, Y. H.; Ohnishi, M.
10.1101/2020.10.26.354993 — microbiology — Posted on 2020-10-26
734 Protective Antibodies Against Human Parainfluenza Virus Type 3 (HPIV3) Infection
Boonyaratanakornkit, J.; Singh, S.; Weidle, C.; Rodarte, J.; Bakthavatsalam, R.; Perkins, J.; Stewart-Jones, G. B. E.; Kwong, P. D.; McGuire, A. T.; Pancera, M.; Taylor, J. J.
10.1101/2020.06.15.153478 — immunology — Posted on 2020-10-26
738 Integrating indigenous knowledge, ontology, and molecular barcoding to characterize spider monkey (Ateles paniscus) filariasis
Milstein, M. S.; Shaffer, C. A.; Lindsey, L. L.; Wolf, T. M.; Suse, P.; Marawanaru, E.; Kipp, E. J.; Garwood, T.; Travis, D. A.; Terio, K. A.; Larsen, P. A.
10.1101/2020.10.26.354985 — evolutionary biology — Posted on 2020-10-26
741 Mechanism and functional role of the interaction between CP190 and the architectural protein Pita in Drosophila melanogaster
Georgiev, P.; Sabirov, M.; Kyrchanova, O.; Pokholkova, G. V.; Bonchuk, A.; Klimenko, N.; Belova, E.; Zhimulev, I. F.; Maksimenko, O.
10.1101/2020.10.26.355016 — molecular biology — Posted on 2020-10-26
744 SETD2 regulates the methylation of translation elongation factor eEF1A1 in clear cell renal cell carcinoma
Hapke, R.; Venton, L.; Rose, K. L.; Sheng, Q.; Reddy, A.; Jones, A.; Rathmell, W. K.; Haake, S. M.
10.1101/2020.10.26.354902 — cancer biology — Posted on 2020-10-26
746 Explainable AI reveals changes in skin microbiome compositionlinked to phenotypic differences
Carrieri, A. P.; Haiminen, N.; Maudsley-Barton, S.; Gardiner, L.-J.; Murphy, B.; Mayes, A.; Paterson, S.; Grimshaw, S.; Winn, M.; Shand, C.; Rowe, W.; Hawkins, S.; MacGuire-Flanagan, A.; Tazzioli, J.; Kenny, J.; Parida, L.; Hoptroff, M.; Pyzer-Knapp, E. O.
10.1101/2020.07.02.184713 — bioinformatics — Posted on 2020-10-26
750 Origin of imported SARS-CoV-2 strains in The Gambia identified from whole genome sequences
Kanteh, A.; Manneh, J.; Jabang, S.; Mariama A., K.; Bakary, S.; Mary A., O.; Bojang, A.; Jallow, H.; Nwakanma, D.; Secka, O.; Rocca, A.; Amambua-Ngwa, A.; Antonio, M.; Baldeh, I.; Forrest, K.; Samateh, A. L.; DAlessandro, U.; Sesay, A. K.
10.1101/2020.10.26.354969 — genomics — Posted on 2020-10-26
752 UNC-45A Weakens and Breaks MT Lattice Independent of its Effect on Non-Muscle Myosin II
Bazzaro, M.; Habicht, J.; Mooneyham, A.; Hoshino, A.; Shetty, M.; Zhang, X.; Emmings, E.; Yang, Q.; Coombes, C.; Gardner, M. K.
10.1101/2020.06.20.163048 — cell biology — Posted on 2020-10-26
758 Characterisation of growth plate dynamics in murine models of osteoarthritis
Samvelyan, H. J.; Madi, K.; Tornqvist, A. E.; Javaheri, B.; Staines, K. A.
10.1101/2020.10.14.339119 — physiology — Posted on 2020-10-26
760 Roughness and dynamics of proliferating cell fronts as a probe of cell-cell interactions
Rapin, G.; Caballero, N.; Gaponenko, I.; Ziegler, B.; Rawleight, A.; Moriggi, E.; Giamarchi, T.; Brown, S. A.; Paruch, P.
10.1101/2020.10.26.354878 — biophysics — Posted on 2020-10-26
764 Epigenetic mechanisms mediating cell state transitions in chondrocytes.
Wuelling, M.; Neu, C.; Thiesen, A. M.; Kitanovski, S.; Cao, Y.; Lange, A.; Westendorf, A. M.; Hoffmann, D.; Vortkamp, A.
10.1101/2020.10.26.319822 — developmental biology — Posted on 2020-10-26
765 Buprenorphine exposure alters the development and migration of interneurons in the cortex
Nieto-Estevez, V.; Donegan, J. J.; McMahon, C.; Elam, H. B.; Chavera, T. A.; Varma, P.; Berg, K. A.; Lodge, D. J.; Hsieh, J.
10.1101/2020.10.26.356022 — developmental biology — Posted on 2020-10-26
766 Seipin traps triacylglycerols to facilitate their nanoscale clustering in the ER membrane
Prasanna, X.; Salo, V. T.; Li, S.; Ven, K.; Vihinen, H.; Jokitalo, E.; Vattulainen, I.; Ikonen, E.
10.1101/2020.10.26.355065 — cell biology — Posted on 2020-10-26
767 Oxidised phosphatidylcholines induce multiple functional defects in airway epithelial cells
Pascoe, C. D.; Roy, N.; Turner-Brannen, E.; Schultz, A.; Vaghasiya, J.; Ravandi, A.; Halayko, A. J.; West, A. R.
10.1101/823666 — cell biology — Posted on 2020-10-26
769 Phosphorylation on PstP regulates cell wall metabolism and antibiotic tolerance in Mycobacterium smegmatis
Shamma, F.; Papavinasasundaram, K.; Quintanilla, S. Y.; Bandekar, A.; Sassetti, C. M.; Boutte, C. C.
10.1101/825588 — microbiology — Posted on 2020-10-26
770 Comparison of the in vitro-efficacy of different mouthwash solutions targeting SARS-CoV-2 based on the European Standard EN 14476
Steinhauer, K.; Meister, T. L.; Todt, D.; Krawczyk, A.; Passvogel, L.; Becker, B.; Paulmann, D.; Bischoff, B.; Pfaender, S.; Brill, F.; Steinmann, E.
10.1101/2020.10.25.354571 — microbiology — Posted on 2020-10-26
771 Post-exposure protection of SARS-CoV-2 lethal infected K18-hACE2 transgenic mice by neutralizing human monoclonal antibody
Rosenfeld, R.; Noy-Porat, T.; Mechaly, A.; Makdasi, E.; Levy, Y.; Alcalay, R.; Falach, R.; Aftalion, M.; Epstein, E.; Gur, D.; Chitlaru, T.; Vitner, E. B.; Melamed, S.; Politi, B.; Zauberman, A.; Lazar, S.; Evgy, Y.; Yitzhaki, S.; Shapira, S. C.; Israely, T.; Mazor, O.
10.1101/2020.10.26.354811 — immunology — Posted on 2020-10-26
772 Intra-axonal translation of Khsrp mRNA slows axon regeneration by destabilizing localized mRNAs
Patel, P.; Buchanan, C.; Kar, A. N.; Lee, S. J.; Urisman, A.; Sahoo, P. K.; Oses-Prieto, J. A.; Dell Orco, M.; Cassiday, D. E.; Miller, S.; Thames, E.; Smith, T. P.; Zdradzinski, M. D.; Burlingame, A.; Perrone-Bizzozero, N.; Twiss, J. L.
10.1101/2020.10.26.356162 — neuroscience — Posted on 2020-10-26
774 Multi-model evaluation of phenology prediction for wheat in Australia
Wallach, D.; Palosuo, T.; Thorburn, P.; Hochman, Z.; Andrianasolo, F.; Asseng, S.; Basso, B.; Buis, S.; Crout, N.; Dumont, B.; Ferrise, R.; Gaiser, T.; Gayler, S.; Hiremath, S.; Hoek, S.; Horan, H.; Hoogenboom, G.; Huang, M.; Jabloun, M.; Jansson, P.-E.; Jing, Q.; Justes, E.; Kersebaum, K. C.; Launay, M.; Lewan, E.; Luo, Q.; Maestrini, B.; Moriondo, M.; Padovan, G.; Olesen, J. E.; Poyda, A.; Priesack, E.; Pullens, J. W. M.; Qian, B.; Schütze, N.; Shelia, V.; Souissi, A.; Specka, X.; Srivastava, A. K.; Stella, T.; Streck, T.; Trombi, G.; Wallor, E.; Wang, J.; Weber, T. K. D.; Weihermüller, L.
10.1101/2020.06.06.133504 — plant biology — Posted on 2020-10-26
775 Chromatin accessibility profiles of castration-resistant prostate cancers reveal novel subtypes and therapeutic vulnerabilities
Tang, F.; Wang, S.; Wong, C. K.; Lee, C. J.; Cohen, S.; Park, J.; Hill, C. E.; Eng, K.; Bareja, R.; Han, T.; Liu, E. M.; Palladino, A.; Di, W.; Gao, D.; Abida, W.; Beg, S.; Puca, L.; Berger, M. F.; Gopalan, A.; Dow, L. E.; Mosquera, J. M.; Beltran, H.; Sternberg, C. N.; Chi, P.; Scher, H. I.; Sboner, A.; Chen, Y.; Khurana, E.
10.1101/2020.10.26.355925 — cancer biology — Posted on 2020-10-26
777 Synergistic Combination of Cytotoxic Chemotherapy and Cyclin Dependent Kinase 4/6 Inhibitors in Biliary Tract Cancers
Arora, M.; Bogenberger, J. M.; Abdelrahman, A. M.; Yonkus, J.; Alva-Ruiz, R.; Leiting, J. L.; Chen, X.; Serrano Uson, P. L.; Dumbauld, C. R.; Baker, A. T.; Gamb, S. I.; Egan, J. B.; Zhou, Y.; Nagalo, B. M.; Meurice, N.; Eskelinen, E.-L.; Salomao, M.; Kosiorek, H. E.; Braggio, E.; Barrett, M. T.; Buetow, K.; Sonbol, M. B.; Mansfield, A. S.; Roberts, L. R.; Bekaii-Saab, T. S.; Ahn, D. H.; Truty, M. J.; Borad, M. J.
10.1101/2020.10.26.355727 — cancer biology — Posted on 2020-10-26
778 Deep learning enables fast and dense single-molecule localization with high accuracy
Speiser, A.; Müller, L.-R.; Matti, U.; Obara, C. J.; Legant, W. R.; Kreshuk, A.; Macke, J. H.; Ries, J.; Turaga, S. C.
10.1101/2020.10.26.355164 — biophysics — Posted on 2020-10-26
787 Membrane-Dependent Amyloid Aggregation of Human BAX α9 (173-192)
Price, D. A.; Hill, T. D.; Hutson, K. A.; Rightnowar, B. W.; Moran, S. D.
10.1101/2020.10.20.347567 — biochemistry — Posted on 2020-10-26
788 Ten complete mitochondrial genomes of Gymnocharacini (Stethaprioninae, Characiformes): evolutionary relationships and a repetitive element in the Control Region (D-loop)
Pasa, R.; Menegidio, F. B.; Rodrigues-Oliveira, I. H.; Silva, I. B.; Campos, M. L.; Rocha-Reis, D. A.; Heslop-Harrison, J. S.; Schwarzacher, T.; Kavalco, K. F.
10.1101/2020.10.26.355867 — genomics — Posted on 2020-10-26
789 A transcription start site map in human pancreatic islets reveals functional regulatory signatures
Varshney, A.; Kyono, Y.; Elangovan, V. R.; Wang, C.; Erdos, M. R.; Narisu, N.; Albanus, R. D. O.; Orchard, P.; Stitzel, M. L.; Collins, F. S.; Kitzman, J. O.; Parker, S. C. J.
10.1101/812552 — genomics — Posted on 2020-10-26
791 Elephant Genomes Elucidate Disease Defenses and Other Traits
Tollis, M.; Ferris, E.; Campbell, M. S.; Harris, V. K.; Rupp, S. M.; Harrison, T. M.; Kiso, W. K.; Schmitt, D. L.; Garner, M. M.; Aktipis, C. A.; Maley, C. C.; Boddy, A. M.; Yandell, M.; Gregg, C.; Schiffman, J. D.; Abegglen, L. M.
10.1101/2020.05.29.124396 — evolutionary biology — Posted on 2020-10-26
792 An Eutherian-Specific microRNA Controls the Translation of Satb2 in a Model of Cortical Differentiation
Martins, M.; Galfre, S. G.; Terrigno, M.; Pandolfini, L.; Appolloni, I.; Dunville, K.; Marranci, A.; Rizzo, M.; Mercatanti, A.; Poliseno, L.; Morandin, F.; Pietrosanto, M.; Helmer-Citterich, M.; Malatesta, P.; Vignali, R.; Cremisi, F.
10.1101/2020.10.26.355214 — developmental biology — Posted on 2020-10-26
794 Robust Optical Flow Algorithm for General, Label-free Cell Segmentation
Robitaille, M. C.; Byers, J. M.; Christodoulides, J. A.; Raphael, M. P.
10.1101/2020.10.26.355958 — cell biology — Posted on 2020-10-26
795 A toolbox for imaging RIPK1, RIPK3 and MLKL in mouse and human cells
Samson, A. L.; Fitzgibbon, C.; Patel, K. M.; Hildebrand, J. M.; Whitehead, L.; Rimes, J. S.; Jacobsen, A. V.; Horne, C. R.; Gavin, X. J.; Young, S. N.; Rogers, K. L.; Hawkins, E. D.; Murphy, J. M.
10.1101/2020.10.26.356063 — cell biology — Posted on 2020-10-26
796 Disparate Bone Anabolic Cues Activate Bone Formation by Regulating the Rapid Lysosomal Degradation of Sclerostin Protein
Gould, N. R.; Williams, K. M.; Joca, H. C.; Torre, O. M.; Lyons, J. S.; Leser, J. M.; Srikanth, M. P.; Hughes, M.; Khairallah, R. J.; Feldman, R. A.; Ward, C. W.; Stains, J. P.
10.1101/2020.10.26.355800 — cell biology — Posted on 2020-10-26
798 From the Roundabout of Molecular Events to Nanomaterial-Induced Chronic Inflammation Prediction
Majaron, H.; Kokot, B.; Sebastijanovic, A.; Voss, C.; Podlipec, R.; Zawilska, P.; Berthing, T.; Ballester Lopez, C.; Danielsen, P. H.; Contini, C.; Ivanov, M.; Kriselj, A.; Cotar, P.; Zhou, Q.; Ponti, J.; Zhernovkov, V.; Schneemilch, M.; Doumandji, Z.; Pusnik, M.; Umek, P.; Pajk, S.; Joubert, O.; Schmid, O.; Urbancic, I.; Irmler, M.; Beckers, J.; Lobaskin, V.; Halappanavar, S.; Quirke, N.; Lyubartsev, A.; Vogel, U.; Koklic, T.; Stoeger, T.; Strancar, J.
10.1101/2020.02.27.966036 — molecular biology — Posted on 2020-10-26
800 Three-dimensional biofilm growth supports a mutualism involving matrix and nutrient sharing
Arjes, H. A.; Willis, L. A.; Gui, H.; Xiao, Y.; Peters, J. M.; Gross, C.; Huang, K.
10.1101/2020.10.26.355560 — microbiology — Posted on 2020-10-26
802 The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeutic efficacy of the antibody
Chan, C. E. Z.; Seah, S. G. K.; Chye, D. H.; Massey, S.; Torres, M.; Lim, A. P. C.; Wong, S. K. K.; Neo, J. J. Y.; Wong, P. S.; Lim, J. H.; Loh, G. S. L.; Wang, D. L.; Boyd-Kirkup, J. D.; Guan, S.; Thakkar, D.; Teo, G. H.; Purushotorman, K.; Hutchinson, P. E.; Young, B.; Lye, D. C. B.; Low, J. G.; MacAry, P. A.; Hentze, H.; Prativadibhayankara, V. S.; Ethirajulu, K.; O'Connell, D.; Comer, J.; Tseng, C.-T. K.; Barrett, A. D. T.; Ingram, P. J.; Brasel, T.; Hanson, B. J.
10.1101/2020.10.26.355107 — microbiology — Posted on 2020-10-26
803 SARS-CoV-2 specific memory T lymphocytes from COVID-19 convalescent donors: identification, biobanking and large scale production for Adoptive Cell Therapy
Ferreras, C.; Pascual-Miguel, B.; Mestre-Duran, C.; Navarro-Zapata, A.; Clares-Villa, L.; Martin-Cortazar, C.; De Paz, R.; Marcos, A.; Vicario, J. L.; Balas, A.; Garcia-Sanchez, F.; Eguizabal, C.; Solano, C.; Mora-Rillo, M.; Soria, B.; Perez-Martinez, A.
10.1101/2020.10.23.352294 — immunology — Posted on 2020-10-26
806 Near-optimal rotation of colour space by zebrafish cones in vivo
Yoshimatsu, T.; Bartel, P.; Schröder, C.; Janiak, F. K.; St-Pierre, F.; Berens, P.; Baden, T.
10.1101/2020.10.26.356089 — neuroscience — Posted on 2020-10-26
807 ZeBraInspector, a whole organism screening platform enabling volumetric analysis of zebrafish brain white matter
Lempereur, S.; Machado, E.; Licata, F.; Buzer, L.; Robineau, I.; Hémon, J.; Banerjee, P.; De Crozé, N.; Léonard, M.; Affaticati, P.; Jenett, A.; Talbot, H.; Joly, J.-S.
10.1101/2020.10.26.353656 — neuroscience — Posted on 2020-10-26
808 TRPV1 feed-forward sensitisation depends on COX2 upregulation in primary sensory neurons
Li, T.; Wang, G.; Hui, V. C. C.; Saad, D.; de Sousa Valente, J.; La Montanara, P.; Nagy, I.
10.1101/2020.09.05.267708 — neuroscience — Posted on 2020-10-26
810 Time scale separation of information processing between sensory and associative regions
Sorrentino, P.; Rabuffo, G.; Rucco, R.; Baselice, F.; Troisi Lopez, E.; Liparoti, M.; Quarantelli, M.; Sorrentino, G.; Bernard, C.; Jirsa, V.
10.1101/2020.10.23.350322 — neuroscience — Posted on 2020-10-26
811 Multi-contrast Anatomical Subcortical Structures Parcellation
Bazin, P.-L.; Alkemade, A.; Mulder, M.; Henry, A. G.; Forstmann, B.
10.1101/2020.05.26.115865 — neuroscience — Posted on 2020-10-26
813 Three-fluorophore FRET enables the analysis of ternary protein association in living plant cells
Gloeckner, N.; zur Oven-Krockhaus, S.; Rohr, L.; Wackenhut, F.; Burmeister, M.; Wanke, F.; Holzwart, E.; Meixner, A. J.; Wolf, S.; Harter, K.
10.1101/722124 — plant biology — Posted on 2020-10-26
816 Deep Graph Pose: a semi-supervised deep graphical model for improved animal pose tracking
Wu, A.; Buchanan, E. K.; Whiteway, M. R.; Schartner, M.; Meijer, G. T.; Noel, J.-P.; Rodriguez, E.; Everett, C.; Norovich, A.; Schaffer, E. S.; Mishra, N.; Salzman, C. D.; Angelaki, D. E.; International Brain Laboratory, T.; Cunningham, J. P.; Paninski, L.
10.1101/2020.08.20.259705 — animal behavior and cognition — Posted on 2020-10-26
817 The genomic epidemiology of SARS-CoV-2 in Palestine
Qutob, N.; Salah, Z.; Richard, D.; Darwish, H.; Sallam, H.; Shtayeh, I.; Najjar, O.; Balloux, F.; van Dorp, L.
10.1101/2020.10.26.355677 — genomics — Posted on 2020-10-26
819 New mechanism of fibronectin fibril assembly revealed by live imaging and super-resolution microscopy.
Tomer, D.; Munshi, S.; Alexander, B.; French, B.; Vedula, P.; House, A.; Guvendiren, M.; Kashina, A.; Schwarzbauer, J.; Astrof, S.
10.1101/2020.09.09.290130 — cell biology — Posted on 2020-10-26
820 Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome
Bhatt, P. R.; Scaiola, A.; Loughran, G.; Leibundgut, M.; Kratzel, A.; McMillan, A. E.; O'Connor, K. M.; Bode, J. W.; Thiel, V.; Atkins, J. F.; Ban, N.
10.1101/2020.10.26.355099 — molecular biology — Posted on 2020-10-26
822 RNAmining: A machine learning stand-alone and web server tool for RNA coding potential prediction
Ramos, T.; Galindo, N.; Arias-Carrasco, R.; da Silva, C.; Maracaja-Coutinho, V.; do Rego, T.
10.1101/2020.10.26.354357 — bioinformatics — Posted on 2020-10-26
823 An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7
Rai, J.; Parker, M. D.; Huang, H.; Choi, S.; Ghalei, H.; Johnson, M. C.; Karbstein, K.; Stroupe, M. E.
10.1101/617910 — biochemistry — Posted on 2020-10-26
826 Association between vitamin D deficiency and exercise capacity in patients with CKD, a cross-sectional analysis
Watson, E. L.; Wilkinson, T.; O'Sullivan, T.; Baker, L.; Gould, D.; Xenophontos, S.; Graham-Brown, M.; Major, R.; Jenkinson, C.; Hewison, M.; Philp, A.; Smith, A.
10.1101/2020.10.26.350546 — cell biology — Posted on 2020-10-26
827 Ca2+ signaling driving pacemaker activity in submucosal interstitial cells of Cajal in the colon
Baker, S.; Leigh, W. A.; De Yturriaga, I. F.; Ward, S. M.; Cobine, C. A.; Drumm, B. T.; Sanders, K.
10.1101/2020.10.26.355404 — cell biology — Posted on 2020-10-26
828 Direct RNA-RNA interaction between Neat1 and RNA targets, as a mechanism for RNAs paraspeckle retention
Jacq, A.; Becquet, D.; Guillen, S.; Boyer, B.; Bello-Goutierrez, M.-M.; Franc, J.-L.; Francois-Bellan, A.-M.
10.1101/2020.10.26.354712 — molecular biology — Posted on 2020-10-26
829 Homeodomain protein 1 is an essential regulator of gene expression during sexual differentiation of malaria parasites
Campelo Morillo, R.; Tong, X.; Xie, W.; Lenz, T.; Batugedara, G.; Tabassum, N.; Orchard, L. M.; Daher, W.; Patel, D.; Noble, W. S.; Llinas, M.; Le Roch, K. G.; Kafsack, B. F. C.
10.1101/2020.10.26.352583 — microbiology — Posted on 2020-10-26
832 The Big Five personality traits and CNS arousal in the resting state
Jawinski, P.; Markett, S.; Sander, C.; Huang, J.; Ulke, C.; Hegerl, U.; Hensch, T.
10.1101/2020.10.26.354647 — neuroscience — Posted on 2020-10-26
833 Allantoin induces pruritus by activating MrgprD in chronic kidney disease
Tang, Z.; yang, y.; sun, y.; guan, d.; chen, d.; wang, d.; liu, t.; sheng, m.; tao, j.; shi, j.; zhu, c.; Yu, G.; Dong, X.
10.1101/2020.10.26.354654 — pathology — Posted on 2020-10-26
834 Loss of erythroblasts in acute myeloid leukemia causes iron redistribution with clinical implications
Lopes, M.; Duarte, T.; Teles, M. J.; Mosteo, L.; Chacim, S.; Aguiar, E.; Pereira-Reis, J.; Oliveira, M.; Silva, A. M. N.; Goncalves, N.; Martins, G.; Kong, I.; Zethoven, M.; Vervoort, S.; Martins, S.; Quintela, M.; Hawkins, E.; Trigo, F.; Guimaraes, J. T.; Mariz, J. M.; Porto, G.; Duarte, D.
10.1101/2020.10.26.350116 — cancer biology — Posted on 2020-10-26
837 Systematic GWAS-assessment of disease modules reveals a multi-omic MS module strongly associated with risk factors
Badam, T. V. S.; de Weerd, H. A.; Martinez-Enguita, D.; Olsson, T.; Alfredsson, L.; Kockum, I.; Jagodic, M.; Lubovac-Pilav, Z.; Gustafsson, M.
10.1101/2020.10.26.351783 — bioinformatics — Posted on 2020-10-26
840 Predicting wildlife hosts of betacoronaviruses for SARS-CoV-2 sampling prioritization: a modeling study
Becker, D.; Albery, G. F.; Sjodin, A. R.; Poisot, T.; Dallas, T.; Eskew, E. A.; Farrell, M. J.; Guth, S.; Han, B. A.; Simmons, N. B.; Stock, M.; Teeling, E. C.; Carlson, C. J.
10.1101/2020.05.22.111344 — ecology — Posted on 2020-10-26
841 LncRNA Snhg1-driven self-reinforcing regulatory network promotes cardiomyocyte cytokinesis
Li, M.; zheng, H.; Chen, Y.; Li, B.; Chen, G.; Chen, X.; Huang, S.; He, X.; Wei, G.; Xu, T.; Feng, X.; Liao, W.; Liao, Y.; Chen, Y.; Bin, J.
10.1101/2020.10.26.354613 — developmental biology — Posted on 2020-10-26
843 Natural Cystatin C fragments inhibit GPR15-mediated HIV and SIV infection without interfering with GPR15L signaling
Hayn, M.; Bloetz, A.; Rodriguez-Alfonso, A.; Vidal, S.; Preising, N.; Staendker, L.; Wiese, S.; Stuerzel, C. M.; Harms, M.; Gross, R.; Jung, C.; Kiene, M.; Hahn, B. H.; Jacob, T.; Poehlmann, S.; Forssmann, W.-G.; Muench, J.; Sparrer, K. M.; Seuwen, K.; Kirchhoff, F.
10.1101/2020.10.26.355172 — microbiology — Posted on 2020-10-26
844 At least seven distinct rotavirus genotype constellations in bats with evidence of reassortment and zoonotic transmissions
Simsek, C.; Corman, V. M.; Everling, H. U.; Lukashev, A. N.; Rasche, A.; Maganga, G. D.; Binger, T.; Jansen, D.; Beller, L.; Deboutte, W.; Gloza-Rausch, F.; Seebens-Hoyer, A.; Yordanov, S.; Sylverken, A.; Oppong, S. K.; Abu-Sarkodie, Y.; Vallo, P.; Leroy, E.; Bourgarel, M.; Yinda, K. C.; Van Ranst, M.; Drosten, C.; Drexler, J. F.; Matthijnssens, J.
10.1101/2020.08.13.250464 — microbiology — Posted on 2020-10-26
846 Cellular and genomic properties of Haloferax gibbonsii LR2-5, the host of euryarchaeal virus HFTV1
Tittes, C.; Schwarzer, S.; Pfeiffer, F.; Dyall-Smith, M.; Rodriguez-Franco, M.; Oksanen, H. M.; Quax, T. E. F.
10.1101/2020.10.26.354720 — microbiology — Posted on 2020-10-26
847 SARS-CoV-2 infected cells present HLA-I peptides from canonical and out-of-frame ORFs
Weingarten-Gabbay, S.; Klaeger, S.; Sarkizova, S.; Pearlman, L. R.; Chen, D.-Y.; Bauer, M. R.; Taylor, H. B.; Conway, H. L.; Tomkins-Tinch, C. H.; Finkel, Y.; Nachshon, A.; Gentili, M.; Rivera, K. D.; Keskin, D. B.; Rice, C. M.; Clauser, K. R.; Hacohen, N.; Carr, S. A.; Abelin, J. G.; Saeed, M.; Sabeti, P. C.
10.1101/2020.10.02.324145 — immunology — Posted on 2020-10-26
849 SDF-1/CXCR4 inhibition prevents paradoxical generation of cisplatin-induced pro-metastatic niches
Bertolini, G.; Cancila, V.; Milione, M.; Lo Russo, G.; Fortunato, O.; Zaffaroni, N.; Tortoreto, M.; Centonze, G.; Chiodoni, C.; Facchinetti, F.; Giovinazzo, F.; Moro, M.; Camisaschi, C.; De Toma, A.; D'Alterio, C.; Pastorino, U.; Tripodo, C.; Scala, S.; Sozzi, G.; Roz, L.
10.1101/2020.10.26.355057 — cancer biology — Posted on 2020-10-26
850 A Single-Cell Tumor Immune Atlas for Precision Oncology
Nieto, P.; Marc Elosua-Bayes, M.; Trincado, J. L.; Marchese, D.; Massoni-Badosa, R.; Salvany, M.; Henriques, A.; Mereu, E.; Moutinho, C.; Ruiz, S.; Lorden, P.; Chin, V.; Kaczorowski, D. C.; Chan, C.-L.; Gallagher, R.; Chou, A.; Planas-Rigol, E.; Rubio-Perez, C.; Gut, I. G.; Piulats, J. M.; Seoane, J.; Powell, J.; Batlle, E.; Heyn, H.
10.1101/2020.10.26.354829 — cancer biology — Posted on 2020-10-26
856 Gene validation and remodelling using proteogenomics of Phytophthora cinnamomi, the causal agent of Dieback.
Andronis, C. E.; Hane, J.; Bringans, S.; Hardy, G.; Jacques, S.; Lipscombe, R.; Tan, K.-C.
10.1101/2020.10.25.354530 — genomics — Posted on 2020-10-26
864 Differences in pulmonary innate lymphoid cells are dependent on mouse age, sex and strain
Loering, S.; Cameron, G. J.-M.; Bhatt, N. P.; Belz, G. T.; Foster, P. S.; Hansbro, P. M.; Starkey, M. R.
10.1101/2020.10.25.354464 — immunology — Posted on 2020-10-26
865 ALS monocyte-derived microglia reveal cytoplasmic TDP-43 accumulation, DNA damage, and cell-specific impairment of phagocytosis associated with disease progression.
Quek, H.; Cuni-Lopez, C.; Stewart, R.; Colletti, T.; Notaro, A.; Sun, Y.; Guo, C. C.; Lupton, M. K.; Nguyen, T. H.; Oikari, L. E.; Roberts, T. L.; Lim, Y. C.; La Bella, V.; White, A. R.
10.1101/2020.10.25.354399 — neuroscience — Posted on 2020-10-26
868 SIPEC: the deep-learning Swiss knife for behavioral data analysis
Marks, M.; Qiuhan, J.; Sturman, O.; von Ziegler, L.; Kollmorgen, S.; von der Behrens, W.; Mante, V.; Bohacek, J.; Yanik, M. F.
10.1101/2020.10.26.355115 — neuroscience — Posted on 2020-10-26
871 Bombesin-like peptide recruits disinhibitory cortical circuits and enhances fear memories
Melzer, S.; Newmark, E.; Mizuno, G.; Hyun, M.; Philson, A. C.; Quiroli, E.; Righetti, B.; Gregory, M.; Huang, K. W.; Levasseur, J.; Tian, L.; Sabatini, B.
10.1101/2020.10.26.355123 — neuroscience — Posted on 2020-10-26
874 The Arabidopsis E3 ubiquitin ligase PUB4 regulates BIK1 homeostasis and is targeted by a bacterial type-III effector
Derkacheva, M.; Yu, G.; Rufian, J. S.; Jiang, S.; Derbyshire, P.; Morcillo, R.; Stransfeld, L.; Wei, Y.; Menke, F.; Zipfel, C.; Macho, A.
10.1101/2020.10.25.354514 — plant biology — Posted on 2020-10-26
875 Ultra-fast Prediction of Somatic Structural Variations by Reduced Read Mapping via Pan-Genome k-mer Sets
Choi, M.-H.; Sohn, J.-i.; Yi, D.; Menon, A. V.; Kim, Y. J.; Kyoung, S.; Shin, S.-H.; Na, B.; Joung, J.-G.; Yoon, S.; Koh, Y.; Baek, D.; Kim, T.-M.; Nam, J.-W.
10.1101/2020.10.25.354456 — bioinformatics — Posted on 2020-10-26
876 Biological insights from the whole genome analysis of human embryonic stem cells
Merkle, F. T.; Ghosh, S.; Genovese, G.; Handsaker, R. E.; Kashin, S.; Karczewski, K.; O'Dushlaine, C.; Pato, C.; Pato, M.; MacArthur, D.; McCarroll, S. A.; Eggan, K.
10.1101/2020.10.26.337352 — genomics — Posted on 2020-10-26
877 Single-cell profiling of tuberculosis lung granulomas reveals functional lymphocyte signatures of bacterial control
Gideon, H. P.; Hughes, T. K.; Wadsworth, M. H.; Tu, A. A.; Gierahn, T. M.; Hopkins, F. H.; Wei, J.-R.; Kummerlowe, C.; Grant, N. L.; Nargan, K.; Phuah, J.; Borish, H. J.; Maiello, P.; White, A. G.; Ganchua, S. K. C.; Myers, A.; Ameel, C.; Cochran, C. T.; Nyquist, S. K.; Peters, J. M.; Tomko, J. A.; Frye, L. J.; Rosenberg, J.; Shih, A.; Chao, M.; Scanga, C.; Ordovas-Montanes, J.; Berger, B.; Mattila, J. T.; Madansein, R.; Love, J. C.; Bryson, B. D.; Lin, P. L.; Leslie, A.; Behar, S. M.; Flynn, J. L.; Fortune, S. M.; Shalek, A. K.
10.1101/2020.10.24.352492 — immunology — Posted on 2020-10-26
878 A novel equilibrative nucleoside transporter 1 inhibitor alleviates Tau-mediated neurodegeneration
Chang, C.-P.; Chang, Y.-G.; Chuang, P.-Y.; Nguyen, A. T. N.; Chou, F.-Y.; Cheng, S.-J.; Chen, H.-M.; Jin, L.-W.; Carvalho, K.; Huin, V.; Buee, L.; Blum, D.; Liao, Y.-F.; Lin, C.-J.; Chern, Y.
10.1101/2020.10.25.334201 — neuroscience — Posted on 2020-10-26
879 Newly developed silicone airway stent (GINA stent): Mechanical characteristics and performance evaluation in pigs
Jung, H. S.; Chae, G.; Kim, J. H.; Bae, S.; Park, C. Y.; Lim, S.; Park, S. E.; Jung, M. S.; Park, J. I.; Lee, Y. J.; Kang, S. K.; Kim, D. H.; Lee, Y.; Lee, T.
10.1101/2020.10.24.343533 — physiology — Posted on 2020-10-26
880 Disruption of a GATA2, TAL1, ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells
Thoms, J. A.; Knezevic, K.; Harvey, G.; Huang, Y.; Seneviratne, J.; Carter, D. R.; Subramanian, S.; Skhinas, J.; Chacon, D.; Shah, A.; de Jong, I.; Beck, D.; Gottgens, B.; Larsson, J.; Wong, J. W.; Zanini, F.; Pimanda, J. E.
10.1101/2020.10.26.353797 — cancer biology — Posted on 2020-10-26
882 Structural basis of rotavirus RNA chaperone displacement and RNA annealing
Bravo, J. P. K.; Bartnik, K.; Venditti, L.; Gail, E. H.; Davidovich, C.; Lamb, D. C.; Tuma, R.; Calabrese, A. N.; Borodavka, A.
10.1101/2020.10.26.354233 — biophysics — Posted on 2020-10-26
884 Distinct autoinhibitory mechanisms regulate vinculin binding by alpha-T-catenin and alpha-E-catenin
Heier, J. A.; Pokutta, S.; Dale, I. W.; Kim, S. K.; Hinck, A. P.; Weis, W. I.; Kwiatkowski, A. V.
10.1101/2020.10.25.354415 — biochemistry — Posted on 2020-10-26
885 Structure of transmembrane prolyl 4-hydroxylase reveals unique organization of EF and dioxygenase domains
Myllykoski, M.; Sutinen, A.; Koski, M. K.; Kallio, J. P.; Raasakka, A.; Myllyharju, J.; Wierenga, R. K.; Koivunen, P.
10.1101/2020.10.25.354423 — biochemistry — Posted on 2020-10-26
889 Sea-crossing along migratory flyways is limited more strongly by wind than by lack of uplift
Nourani, E.; Becciu, P.; Bierregaard, R. O.; Duriez, O.; Giokas, S.; Higuchi, H.; Kassara, C.; Kulikova, O.; Lecomte, N.; Monti, F.; Pokrovsky, I.; Sforzi, A.; Therrien, J.-F.; Tsiopelas, N.; Yamaguchi, N. M.; Wikelski, M.; Safi, K.
10.1101/2020.09.04.282939 — animal behavior and cognition — Posted on 2020-10-26
892 Trade-off between plasticity and velocity in mycelial growth
Fukuda, S.; Yamamoto, R.; Yanagisawa, N.; Takaya, N.; Sato, Y.; Riquelme, M.; Takeshita, N.
10.1101/2020.10.25.354373 — microbiology — Posted on 2020-10-26
893 The Histoplasma capsulatum DDR48 Gene Is Required For Survival Within Macrophages, Response To Oxidative Stress, And Resistance to Antifungal Drugs
Blancett, L. T.; Runge, K. A.; Reyes, G. M.; Kennedy, L. A.; Jackson, S. C.; Scheuermann, S. E.; Harmon, M. B.; Williams, J. C.; Shearer, G.
10.1101/2020.10.25.354308 — microbiology — Posted on 2020-10-26
895 Acoustic stimulation increases implicit adaptation in sensorimotor adaptation
Leow, L.-A.; Tresilian, J.; Uchida, A.; Koester, D.; Spingler, T.; Riek, S.; Marinovic, W.
10.1101/2020.10.25.354340 — neuroscience — Posted on 2020-10-26
901 Dynamic Bayesian networks for integrating multi-omics time-series microbiome data
Ruiz-Perez, D.; Lugo-Martinez, J.; Bourguignon, N.; Mathee, K.; Lerner, B.; Bar-Joseph, Z.; Narasimhan, G.
10.1101/835124 — bioinformatics — Posted on 2020-10-26
903 FIREcaller: Detecting Frequently Interacting Regions from Hi-C Data
Crowley, C.; Yang, Y.; Qiu, Y.; Hu, B.; Lipinski, J.; Plewczynski, D.; Won, H.; Ren, B.; Hu, M.; Li, Y.
10.1101/619288 — bioinformatics — Posted on 2020-10-26
905 Functional Organization of the Maternal and Paternal Human 4D Nucleome
Lindsly, S. M.; Jia, W.; Chen, H.; Liu, S.; Ronquist, S.; Chen, C.; Wen, X.; Dotson, G.; Ryan, C.; Omenn, G. S.; Li, S. C.; Wicha, M.; Rehemtulla, A.; Muir, L.; Rajapakse, I.
10.1101/2020.03.15.992164 — genomics — Posted on 2020-10-26
907 TCR affinity controls the dynamics but not the functional specification of the Th1 response to mycobacteria
Bhattacharyya, N. D.; Counoupas, C.; Daniel, L.; Zhang, G.; Cook, S. J.; Cootes, T. A.; Stifter, S. A.; Bowen, D. G.; Bertolino, P.; Britton, W. J.; Feng, C. G.
10.1101/2020.10.25.353763 — immunology — Posted on 2020-10-26
909 Comprehension of computer code relies primarily on domain-general executive brain regions
Ivanova, A. A.; Srikant, S.; Sueoka, Y.; Kean, H. H.; Dhamala, R.; O'Reilly, U.-M.; Bers, M. U.; Fedorenko, E.
10.1101/2020.04.16.045732 — neuroscience — Posted on 2020-10-26
911 In situ detection of protein interactions for recombinant therapeutic enzymes
Samoudi, M.; Kuo, C.-C.; Robinson, C. M.; Shams-Ud-Doha, K.; Schinn, S.-M.; Kol, S.; Weiss, L.; Petersen Bjorn, S.; Voldborg, B. G.; Rosa Campos, A.; Lewis, N. E.
10.1101/2020.05.06.081885 — synthetic biology — Posted on 2020-10-26
912 CaMKII binds both substrates and effectors at the active site
Ozden, C.; Sloutsky, R.; Santos, N.; Agnello, E.; Gaubitz, C.; Esposito, E. A.; Lapinskas, E.; Kelch, B. A.; Garman, S. C.; Hayashi, Y.; Stratton, M.
10.1101/2020.10.25.354241 — biochemistry — Posted on 2020-10-26
915 Cross Sectional Study Of Middle East Respiratory Syndrome (MERS-CoV Infection) In Camels At Selected Sites Of Amibara District, Afar Region, Ethiopia
Lobago, D. S.; Mamo, G.; Aklilu, F.; Zewde, D.; Walelign, E.; Muluneh, A.; Aliy, A.; Mirkena, T.; Tewolde, N.; Gari, G.; van't Klooster, G.; Elmasry, I.; VonDobschuetz, S.; Peiris, J. S. M. S.; Chu, D. K. W.; Perera, R. A. P. M.; Jobire, Y.
10.1101/2020.10.25.353227 — microbiology — Posted on 2020-10-25
916 The allosteric modulation of Complement C5 by knob domain peptides
Macpherson, A.; Laabei, M.; Ahdash, Z.; Graewert, M. A.; Birtley, J.; Schulze, S.; Crennell, S.; Robinson, S.; Holmes, B.; Oleinikovas, V.; Nilsson, P. H.; Snowden, J.; Ellis, V.; Mollnes, T. E.; Deane, C. M.; Svergun, D. I.; Lawson, A.; van den Elsen, J.
10.1101/2020.10.24.353714 — immunology — Posted on 2020-10-25
917 Loss of KHSRP Increases Neuronal Growth and Synaptic Transmission and Alters Memory Consolidation Through RNA Stabilization
Olguin, S. L.; Patel, P.; Dell Orco, M.; Gardiner, A. S.; Cole, R. D.; Buchanan, C.; Sundara, A.; Mudge, J.; Allan, A. M.; Ortinski, P.; Brigman, J. L.; Twiss, J. L.; Perrone-Bizzozero, N.
10.1101/2020.10.25.354076 — neuroscience — Posted on 2020-10-25
918 Diurnal changes in perineuronal nets and parvalbumin neurons in the rat medial prefrontal cortex
Harkness, J. H.; Gonzalez, A. E.; Bushana, P. N.; Jorgensen, E. T.; Hegarty, D. M.; Di Nardo, A. A.; Prochiantz, A.; Wisor, J. P.; Aicher, S. A.; Brown, T. E.; Sorg, B. A.
10.1101/2020.10.25.354134 — neuroscience — Posted on 2020-10-25
919 Statistical learning occurs during practice while high-order rule learning during rest period
Quentin, R.; Fanuel, L.; Kiss, M.; Vernet, M.; Vekony, T.; Janacsek, K.; Cohen, L.; Nemeth, D.
10.1101/2020.10.25.353375 — neuroscience — Posted on 2020-10-25
920 Transcriptional Diversity of Medium Spiny Neurons in the Primate Striatum
He, J.; Kleyman, M.; Chen, J.; Alikaya, A.; Rothenhoefer, K. M.; Ozturk, B. E.; Wirthlin, M.; Fish, K.; Byrne, L. C. T.; Pfenning, A. R.; Stauffer, W. R.
10.1101/2020.10.25.354159 — neuroscience — Posted on 2020-10-25
921 Sleep spindles coordinate corticostriatal reactivations during the emergence of automaticity
Lemke, S. M.; Ramanathan, D. S.; Darevsky, D.; Egert, D. G.; Berke, J.; Ganguly, K.
10.1101/2020.10.25.354282 — neuroscience — Posted on 2020-10-25
922 RNF5 Regulation of RBBP4 Defines Acute Myeloid Leukemia Growth and Susceptibility to Histone Deacetylase Inhibitors
Khateb, A.; Deshpande, A.; Feng, Y.; Lee, J. S.; Lazar, I.; Fabre, B.; Li, Y.; Finlay, D.; Fujita, Y.; Zhang, T.; Yin, J.; Pass, I.; Livneh, I.; Burian, C.; Mason, J. R.; Almog, R.; Horesh, N.; Ofran, Y.; Brown, K.; Vuori, K.; Jackson, M.; Ruppin, E.; Deshpande, A. J.; Ronai, Z. A.
10.1101/2020.10.25.349241 — cancer biology — Posted on 2020-10-25
923 Quantitative phase microscopy enables precise and efficient determination of biomolecular condensate composition
McCall, P. M.; Kim, K.; Fritsch, A. W.; Iglesias-Artola, J. M.; Jawerth, L. M.; Wang, J.; Ruer, M.; Peychl, J.; Poznyakovskiy, A.; Guck, J.; Alberti, S.; Hyman, A. A.; Brugues, J.
10.1101/2020.10.25.352823 — biophysics — Posted on 2020-10-25
926 Deciphering the mechanism underlying circRNA-mediated immune responses of western honeybees to Nosema ceranae infection
Chen, H.; Du, Y.; Zhu, Z.; Wang, J.; Zhou, D.; Fan, Y.; Jiang, H.; Fan, X.; Xiong, C.; Zheng, Y.; Chen, D.; Guo, R.
10.1101/2020.10.25.353938 — genomics — Posted on 2020-10-25
927 The RNA Structurome in the Asexual Blood Stages of Malaria Pathogen Plasmodium falciparum
Alvarez, D. R. A.; Ospina, A.; Dey, A.; Barwell, T.; Zheng, B.; Li, C.; Basu, S.; Shi, X.; Kadri, S.; Chakrabarti, K.
10.1101/2020.10.25.354316 — molecular biology — Posted on 2020-10-25
930 Drug self-administration in head-restrained mice for simultaneous multiphoton imaging
Vollmer, K. M.; Doncheck, E. M.; Grant, R. I.; Winston, K. T.; Romanova, E. V.; Bowen, C. W.; Siegler, P. N.; Bobadilla, A.-C.; Trujillo-Pisanty, I.; Kalivas, P. W.; Otis, J. M.
10.1101/2020.10.25.354209 — neuroscience — Posted on 2020-10-25
931 Pallidal deep brain stimulation alters cortico-striatal synaptic communication in dystonic hamsters
Heerdegen, M.; Zwar, M.; Franz, D.; Neubert, V.; Plocksties, F.; Niemann, C.; Timmermann, D.; van Rienen, U.; Paap, M.; Perl, S.; Luettig, A.; Richter, A.; Koehling, R.
10.1101/2020.10.25.353847 — neuroscience — Posted on 2020-10-25
934 Bifidobacteria-mediated immune system imprinting early in life
Henrick, B.; Rodriguez, L.; Tadepally, L. K.; Pou, C.; Henckel, E.; Olin, A.; Wang, J.; Mikes, J.; Tan, Z.; Chen, Y.; Ehrlich, A. M.; Bernhardsson, A. K.; Habimana Mugabo, C.; Ambrosiani, Y.; Gustafsson, A.; Chew, S.; Brown, H. K.; Prambs, J.; Bohlin, K.; Mitchell, R. D.; Underwood, M. A.; Smilowitz, J. T.; German, B. J.; Frese, S. A.; Brodin, P.
10.1101/2020.10.24.353250 — immunology — Posted on 2020-10-25
936 Mechanical competition alters the cellular interpretation of an endogenous genetic programme
Bhide, S.; Gombalova, D.; Mönke, G.; Stegmaier, J.; Zinchenko, V.; Kreshuk, A.; Belmonte, J. M.; Leptin, M.
10.1101/2020.10.15.333963 — developmental biology — Posted on 2020-10-25
937 Evaluation of Zoetis GeneMax Advantage genomic predictions in commercial Bos taurus Angus cattle
Arisman, B. C.; Rowan, T. N.; Thomas, J. M.; Durbin, H. J.; Patterson, D. J.; Decker, J. E.
10.1101/2020.10.23.353144 — genomics — Posted on 2020-10-25
938 AP-4 mediates vesicular transport of the 2-AG endocannabinoid producing enzyme DAGLB
Davies, A. K.; Ziegler, M.; Jumo, H.; Afshar Saber, W.; Ebrahimi-Fakhari, D.; Borner, G. H. H.
10.1101/2020.10.25.353995 — cell biology — Posted on 2020-10-25
941 Decoding subjective emotional arousal from EEG during an immersive Virtual Reality experience
Hofmann, S. M.; Klotzsche, F.; Mariola, A.; Nikulin, V. V.; Villringer, A.; Gaebler, M.
10.1101/2020.10.24.353722 — neuroscience — Posted on 2020-10-25
944 MRS-measured Glutamate versus GABA reflects excitatory versus inhibitory neural activities in awake mice
Takado, Y.; Takuwa, H.; Sampei, K.; Urushihata, T.; Takahashi, M.; Shimojo, M.; Uchida, S.; Nitta, N.; Shibata, S.; Nagashima, K.; Ochi, Y.; Ono, M.; Maeda, J.; Tomita, Y.; Sahara, N.; Near, J.; Aoki, I.; Shibata, K.; Higuchi, M.
10.1101/2020.10.25.353888 — neuroscience — Posted on 2020-10-25
945 Large-scale Gradient Dysfunction of the Functional Connectome in Major Depression
Xia, M.; Liu, J.; Sun, X.; Ma, Q.; Wang, X.; Wei, D.; Chen, Y.; Liu, B.; Huang, C.-C.; Zheng, Y.; Wu, Y.; Chen, T.; Cheng, Y.; Xu, X.; Gong, Q.; Si, T.; Qiu, S.; Lin, C.-P.; Cheng, J.; Tang, Y.; Wang, F.; Qiu, J.; Xie, P.; Li, L.; He, Y.; DIDA-Major Depressive Disorder Working Group,
10.1101/2020.10.24.352153 — neuroscience — Posted on 2020-10-25
950 Mechanically Induced Integrin Ligation Mediates Intracellular Calcium Signaling with Single Pulsating Cavitation Bubbles
Li, F.; Park, T. H.; Sankin, G.; Gilchrist, C.; Liao, D.; Chan, C. U.; Mao, Z.; Hoffman, B. D.; Zhong, P.
10.1101/2020.10.25.353904 — biophysics — Posted on 2020-10-25
966 Oxidants are dispensable for HIF1α stability in hypoxia
Kumar, A.; Vaish, M.; Karuppagounder, S. S.; Gazaryan, I.; Cave, J. W.; Starkov, A. A.; Anderson, E. T.; Zhang, S.; Pinto, J. T.; Rountree, A.; Wang, W.; Sweet, I. R.; Ratan, R. R.
10.1101/2020.05.05.079681 — cell biology — Posted on 2020-10-25
969 Object-Attribute Biclustering for Elimination of Missing Genotypes in Ischemic Stroke Genome-Wide Data
Ignatov, D. I.; Khvorykh, G. V.; Khrunin, A. V.; Nikolic, S.; Shaban, M.; Petrova, E. A.; Koltsova, E. A.; Takelait, F.; Egurnov, D.
10.1101/2020.10.22.349910 — bioinformatics — Posted on 2020-10-25
970 Adhesion-mediated mechanosignaling forces mitohormesis
Tharp, K. M.; Higuchi-Sanabria, R.; Timblin, G.; Ford, B.; Garzon-Coral, C.; Schneider, C.; Muncie, J. M.; Stashko, C.; Daniele, J.; Moore, A. S.; Frankino, P.; Manoli, S.; Shao, H.; Richards, A. L.; Chen, K.-H.; Ku, G. M.; Hellerstein, M.; Saijo, K.; Gestwicki, J.; Nomura, D. K.; Krogan, N. J.; Dunn, A.; Swaney, D.; Dillin, A.; Weaver, V. M.
10.1101/2020.03.06.979583 — cell biology — Posted on 2020-10-25
971 Responses of Neurons in the Medullary Lateral Tegmental Field and Nucleus Tractus Solitarius to Vestibular Stimuli in Conscious Felines
Bielanin, J. P.; Douglas, N. O.; Shulgach, J. A.; McCall, A. A.; Miller, D. M.; Amin, P. R.; Murphey, C. P.; Barman, S. M.; Yates, B. J.
10.1101/2020.10.23.352542 — neuroscience — Posted on 2020-10-25
972 In vivo visualization of propagating α-synuclein pathologies in mouse and marmoset models by a bimodal imaging probe, C05-05
Ono, M.; Takahashi, M.; Shimozawa, A.; Fujinaga, M.; Mori, W.; Nagai, Y.; Mimura, K.; Minamihisamatsu, T.; Uchida, S.; Shimojo, M.; Takado, Y.; Takuwa, H.; Sahara, N.; Zhang, M.-R.; Minamimoto, T.; Hasegawa, M.; Higuchi, M.
10.1101/2020.10.23.349860 — neuroscience — Posted on 2020-10-25
976 In vivo progressive degeneration of Huntington's disease patient-derived neurons reveals human-specific pathological phenotypes
Miguez, A.; Fernandez-Garcia, S.; Monguio-Tortajada, M.; Bombau, G.; Galofre, M.; Garcia-Bravo, M.; Vila, C.; Sanders, P.; Fernandez-Medina, H.; Poquet, B.; Salado-Manzano, C.; Roura, S.; Alberch, J.; Segovia, J. C.; Allen, N. D.; Borras, F. E.; Canals, J. M.
10.1101/2020.10.21.347062 — neuroscience — Posted on 2020-10-25
977 Women show enhanced attractiveness ratings and neural processing of male faces associated with male chemosensory signals
Klinkenberg, I. A. G.; Dobel, C.; Broeckelmann, A.-K.; Plessow, F.; Kirschbaum, C.; Zwitserlood, P.; Junghoefer, M.
10.1101/2020.10.23.352559 — neuroscience — Posted on 2020-10-25
978 Target lipidomics reveals associations between serum sphingolipids and insulin sensitivity by the glucose clamp
Ye, J.; Ye, X.; Jiang, W.; Lu, C.; Geng, X.; Zhao, C.; Ma, Y.; Yang, P.; Lam, S. M.; Shui, G.; Yang, T.; Li, J. Z.; Gong, Y.; Fu, Z.; Zhou, H.
10.1101/2020.10.23.352765 — physiology — Posted on 2020-10-25
981 Exceptional Late Devonian arthropods document the origin of decapod crustaceans
Gueriau, P.; Rak, S.; Broda, K.; Kumpan, T.; Viktoryn, T.; Valach, P.; Zaton, M.; Charbonnier, S.; Luque, J.
10.1101/2020.10.23.352971 — paleontology — Posted on 2020-10-25
985 Inheritance of DNA methylation differences in the mangrove Rhizophora mangle
Mounger, J.; Boquete, M. T.; Schmid, M. W.; Renan, G.; Robertson, M. H.; Voors, S. A.; Langanke, K. L.; Alvarez, M. F.; Wagemaker, N. C. A. M.; Schrey, A. W.; Fox, G. A.; Lewis, D. B.; Lira, C. F.; Richards, C. L.
10.1101/2020.10.24.353482 — genomics — Posted on 2020-10-25
987 H3k27ac-HiChIP in prostate cell lines identifies risk genes for prostate cancer susceptibility
Giambartolomei, C.; Seo, J.-H.; Schwarz, T.; Freund, M. K.; Johnson, R. D.; Spisak, S.; Baca, S. C.; Gusev, A.; Mancuso, N.; Pasaniuc, B.; Freedman, M. L.
10.1101/2020.10.23.352351 — genomics — Posted on 2020-10-25
988 Quantitative trait locus mapping for common scab resistance in a tetraploid potato full-sib population
da Silva Pereira, G.; Mollinari, M.; Qu, X.; Thill, C.; Zeng, Z.-B.; Haynes, K.; Yencho, G. C.
10.1101/2020.10.24.353557 — genetics — Posted on 2020-10-25
992 N-myristoyltransferase: Tracing Steps Backwards to Find a Way Forward
Reddick, D.; Udenwobele, D. I.; Datzkiw, D.; Mukherjee, R.; Varma Shrivastav, S.; Good, S. V.; Shrivastav, A.
10.1101/2020.10.23.352898 — evolutionary biology — Posted on 2020-10-25
994 Free-living psychrophilic bacteria of the genus Psychrobacter are descendents of pathobionts
Welter, D. K.; Ruaud, A.; Henseler, Z. M.; De Jong, H. N.; van Coeverden de Groot, P.; Michaux, J.; Gormezano, L.; Waters, J. L.; Youngblut, N. D.; Ley, R. E.
10.1101/2020.10.23.352302 — microbiology — Posted on 2020-10-25
996 Identification of a new orthonairovirus associated with human febrile illness in China
Ma, J.; Lv, X.-L.; Zhang, X.; Han, S.-Z.; Wang, Z.-D.; Li, L.; Sun, H.-T.; Ma, L.-X.; Cheng, Z.-L.; Shao, J.-W. S.; Chen, C.; Zhao, Y.-H.; Sui, L.; Liu, L.-N.; Qian, J.; Wang, W.; Liu, Q.
10.1101/2020.10.24.353458 — microbiology — Posted on 2020-10-25
997 Trade-Offs Between Antibacterial Resistance and Fitness Cost in the Production of Metallo-β-Lactamase by Enteric Bacteria Manifest as Sporadic Emergence of Carbapenem Resistance in a Clinical Setting.
Cheung, C. H. P.; Alorabi, M.; Hamilton, F.; Takebayashi, Y.; Mounsey, O.; Heesom, K. J.; Williams, P. B.; Williams, M.; Albur, M.; MacGowan, A. P.; Avison, M. B.
10.1101/2020.10.24.353581 — microbiology — Posted on 2020-10-25
1007 Single-molecule FRET dynamics of molecular motors in an ABEL Trap
Dienerowitz, M.; Howard, J. A. L.; Quinn, S. D.; Dienerowitz, F.; Leake, M. C.
10.1101/2020.09.21.306704 — biophysics — Posted on 2020-10-25
1010 The papain-like protease of coronaviruses cleaves ULK1 to disrupt host autophagy
Mohamud, Y.; Chao Xue, Y.; Liu, H.; Seng Ng, C.; Bahreyni, A.; Jan, E.; Luo, H.
10.1101/2020.10.23.353219 — cell biology — Posted on 2020-10-25
1013 Time scale separation of information processing between sensory and associative regions
Sorrentino, P.; Rabuffo, G.; Rucco, R.; Baselice, F.; Troisi Lopez, E.; Liparoti, M.; Quarantelli, M.; Sorrentino, G.; Bernard, C.; Jirsa, V.
10.1101/2020.10.23.350322 — neuroscience — Posted on 2020-10-24
1017 Ivermectin repurposing for COVID-19 therapy: Safety and pharmacokinetic assessment of a novel nasal spray formulation in a pig model
Errecalde, J.; Lifschitz, A.; Vecchioli, G.; Ceballos, L.; Errecalde, F.; Ballent, M.; Marin, G.; Daniele, M.; Turic, E.; Spitzer, E.; Toneguzzo, F.; Gold, S.; Krolewiecki, A.; Alvarez, L.; Lanusse, C.
10.1101/2020.10.23.352831 — pharmacology and toxicology — Posted on 2020-10-24
1019 A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells
Mellott, D.; Tseng, C.-T.; Drelich, A.; Fajtova, P.; Chenna, B. C.; Kostomiris, D.; Hsu, J. C.; Zhu, J.; Taylor, Z.; Tat, V.; Katzfuss, A.; Li, L.; Giardini, M. A.; Skinner, D.; Hirata, K.; Beck, S.; Carlin, A. F.; Clark, A. E.; Berreta, L.; Maneval, D.; Frueh, F.; Hurst, B. L.; Wang, H.; Kocurek, K. I.; Raushel, F. M.; O'Donoghue, A.; Siqueira-Neto, J. L.; Meek, T. D.; McKerrow, J. H.
10.1101/2020.10.23.347534 — biochemistry — Posted on 2020-10-24
1020 Protective Antibodies Against Human Parainfluenza Virus Type 3 (HPIV3) Infection
Boonyaratanakornkit, J.; Singh, S.; Weidle, C.; Rodarte, J.; Bakthavatsalam, R.; Perkins, J.; Stewart-Jones, G. B. E.; Kwong, P. D.; McGuire, A. T.; Pancera, M.; Taylor, J. J.
10.1101/2020.06.15.153478 — immunology — Posted on 2020-10-24
1021 Inhibiting histone acetylation in CREBBP/EP300 mutants leads to synthetic cytotoxicity via repression of homologous recombination.
Kumar, M.; Molkentine, D.; Molkentine, J.; Bridges, K.; Xie, T.; Yang, L.; Hefner, A.; Gao, M.; Frederick, M. J.; Seth, S.; Abdelhakiem, M.; Beadle, B.; Johnson, F. M.; Wang, J.; Shen, L.; Heffernan, T.; Sheth, A.; Ferris, R.; Myers, J. N.; Pickering, C. R.; Skinner, H. D.
10.1101/2020.04.10.028217 — cancer biology — Posted on 2020-10-24
1022 Plant Scaffolds Support Motor Recovery and Regeneration in Rats after Traumatic Spinal Cord Injury
Modulevsky, D. J.; Cuerrier, C. M.; Leblanc-Latour, M.; Hickey, R. J.; Obhi, R.-J. K.; Shore, I.; Galuta, A.; Walker, K. L. A.; Tsai, E. C.; Pelling, A. E.
10.1101/2020.10.21.347807 — bioengineering — Posted on 2020-10-24
1024 Relative time constraints improve molecular dating
Szollosi, G. J.; Hoehna, S.; Williams, T. A.; Schrempf, D.; Daubin, V.; Boussau, B.
10.1101/2020.10.17.343889 — evolutionary biology — Posted on 2020-10-24
1025 Non-Invasive Single-Cell Morphometry in Living Bacterial Biofilms
Zhang, M.; Zhang, J.; Wang, Y.; Wang, J.; Achimovich, A. M.; Acton, S. T.; Gahlmann, A.
10.1101/2020.05.28.120279 — microbiology — Posted on 2020-10-24
1027 Analysis of the Immune Response to Sciatic Nerve Injury Identifies Efferocytosis as a Key Mechanism of Nerve Debridement
Kalinski, A. L.; Yoon, C.; Huffman, L. D.; Duncker, P. C.; Kohen, R.; Passino, R.; Hafner, H.; Johnson, C.; Kawaguchi, R.; Carbajal, K. S.; Jara, J. S.; Hollis, E.; Geschwind, D.; Segal, B.; Giger, R. J.
10.1101/2020.10.23.352872 — neuroscience — Posted on 2020-10-24
1028 Multiscale and multimodal reconstruction of cortical structure and function
Turner, N. L.; Macrina, T.; Bae, J. A.; Yang, R.; Wilson, A. M.; Schneider-Mizell, C.; Lee, K.; Lu, R.; Wu, J.; Bodor, A. L.; Bleckert, A. A.; Brittain, D.; Froudarakis, E.; Dorkenwald, S.; Collman, F.; Kemnitz, N.; Ih, D.; Silversmith, W. M.; Zung, J.; Zlateski, A.; Tartavull, I.; Yu, S.-c.; Popovych, S.; Mu, S.; Wong, W.; Jordan, C. S.; Castro, M.; Buchanan, J.; Bumbarger, D. J.; Takeno, M.; Torres, R.; Mahalingam, G.; Elabbady, L.; Li, Y.; Cobos, E.; Zhou, P.; Suckow, S.; Becker, L.; Paninski, L.; Polleux, F.; Reimer, J.; Tolias, A. S.; Reid, R. C.; Macarico da Costa, N.; Seung, H. S.
10.1101/2020.10.14.338681 — neuroscience — Posted on 2020-10-24
1029 Cross species multi-omics reveals cell wall sequestration and elevated global transcription as mechanisms of boron tolerance in plants
Wang, G.; DiTusa, S. F.; Oh, D.-H.; Herrmann, A. D.; Mendoza-Cozatl, D. G.; O'Neill, M. A.; Smith, A. P.; Dassanayake, M.
10.1101/2020.10.01.321760 — plant biology — Posted on 2020-10-24
1033 The structure of behavioral variation within a genotype
Werkhoven, Z.; Bravin, A.; Skutt-Kakaria, K.; Reimers, P.; Pallares, L. F.; Ayroles, J.; de Bivort, B. L.
10.1101/779363 — neuroscience — Posted on 2020-10-24
1034 Single-cell analyses reveal SARS-CoV-2 interference with intrinsic immune response in the human gut
Triana, S.; Metz Zumaran, C.; Ramirez, C.; Kee, C.; Doldan, P.; Shahraz, M.; Schraivogel, D.; Gschwind, A. R.; Steinmetz, L. M.; Herrmann, C.; Alexandrov, T.; Boulant, S.; Stanifer, M. L.
10.1101/2020.10.21.348854 — immunology — Posted on 2020-10-24
1035 A role of DAO1 in oxidation of IAA amino acid conjugates revealed through metabolite, high throughput transcript and protein level analysis.
Muller, K.; Dobrev, P. I.; Pencik, A.; Hosek, P.; Vondrakova, Z.; Filepova, R.; Malinska, K.; Helusova, L.; Moravec, T.; Retzer, K.; Harant, K.; Novak, O.; Hoyerova, K.; Petrasek, J.
10.1101/2020.10.24.353276 — plant biology — Posted on 2020-10-24
1037 THE MATRIX IS EVERYWHERE: CACO3 BIOMINERALIZATION BY THE BACILLUS LICHENIFORMIS PLANKTONIC CELLS
Ivanova, L. A.; Golovkina, D. A.; Zhurishkina, E. V.; Garmay, Y. P.; Baranchikov, A. Y.; Tsvigun, N. V.; Zabrodskaya, Y. A.; Yapryntsev, A. D.; Gorshkov, A. N.; Lebedev, K. I.; Shaldzhyan, A. A.; Kopitsa, G. P.; Egorov, V. V.; Kulminskaya, A. A.
10.1101/2020.10.22.351619 — microbiology — Posted on 2020-10-24
1043 A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit
Schedlbauer, A.; Iturrioz, I.; Ochoa-Lizarralde, B.; Diercks, T.; Lopez-Alonso, J. P.; Lavin, J. L.; Kaminishi, T.; Capuni, R.; Dhimole, N.; de Astigarraga, E.; Gil-Carton, D.; Fucini, P.; Connell, S. R.
10.1101/2020.10.19.334821 — microbiology — Posted on 2020-10-24
1044 Dual Functions of SPOP and ERG Dictate Androgen Therapy Responses in Prostate Cancer
Bernasocchi, T.; El tekle, G.; Bolis, M.; Mutti, A.; Vallerga, A.; Brandt, L. P.; Spriano, F.; Svinkina, T.; Zoma, M.; Ceserani, V.; Rinaldi, A.; Janouskova, H.; Bossi, D.; Cavalli, M.; Mosole, S.; Geiger, R.; Dong, Z.; Yang, C.-G.; Albino, D.; Rinaldi, A.; Schraml, P.; Linder, S.; Carbone, G. M.; Alimonti, A.; Bertoni, F.; Moch, H.; Carr, S. A.; Zwart, W.; JuliKruithof-deo, M.; Rubin, M.; Udeshi, N.; Theurillat, J. P. P.
10.1101/2020.07.08.193581 — cancer biology — Posted on 2020-10-24
1045 X chromosome-dependent disruption of placental regulatory networks in hybrid dwarf hamsters
Brekke, T. D.; Moore, E. C.; Campbell-Staton, S. C.; Callahan, C. M.; Cheviron, Z. A.; Good, J. M.
10.1101/2020.09.15.298893 — evolutionary biology — Posted on 2020-10-24
1047 Mutation-specific pathophysiological mechanisms define different neurodevelopmental disorders associated with SATB1 dysfunction
den Hoed, J.; Boer, E. d.; Voisin, N.; Dingemans, A.; Guex, N.; Wiel, L.; Nellaker, C.; Amudhavalli, S.; Banka, S.; Bena, F.; Ben-Zeev, B.; Bonagura, V.; Bruel, A.-L.; Brunet, T.; Brunner, H.; Chew, H.; Chrast, J.; Cimbalistien, L.; Coon, H.; Study, T. D.; Delot, E.; Demurger, F.; Denomme-Pichon, A.-S.; Depienne, C.; Donnai, D.; Dyment, D.; Elpeleg, O.; Faivre, L.; Gilissen, C.; Granger, L.; Haber, B.; Hachiya, Y.; Hamzavi Abedi, Y.; Hanebeck, J.; Hehir-Kwa, J.; Horist, B.; Itai, T.; Jackson, A.; Jewell, R.; Jones, K.; Joss, S.; Kashii, H.; Kato, M.; Kattentidt-Mouravieva, A.; Kok, F.; Kotzaer
10.1101/2020.10.23.352278 — genetics — Posted on 2020-10-24
1049 Bifidobacteria-mediated immune system imprinting early in life
Henrick, B.; Rodriguez, L.; Tadepally, L. K.; Pou, C.; Henckel, E.; Olin, A.; Wang, J.; Mikes, J.; Tan, Z.; Chen, Y.; Ehrlich, A. M.; Bernhardsson, A. K.; Habimana Mugabo, C.; Ambrosiani, Y.; Gustafsson, A.; Chew, S.; Brown, H. K.; Prambs, J.; Bohlin, K.; Mitchell, R. D.; Underwood, M. A.; Smilowitz, J. T.; German, B. J.; Frese, S. A.; Brodin, P.
10.1101/2020.10.24.353250 — immunology — Posted on 2020-10-24
1050 A derivative of the D5 monoclonal antibody that targets the gp41 N-heptad repeat of HIV-1 with broad tier-2 neutralizing activity
Rubio, A. A.; Filsinger Interrante, M. V.; Bell, B. N.; Brown, C. L.; LaBranche, C. C.; Montefiori, D. C.; Kim, P. S.
10.1101/2020.10.23.352526 — immunology — Posted on 2020-10-24
1051 Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise
Klein, A. B.; Nicolaisen, T. S.; Ortenblad, N.; Gejl, K. D.; Jensen, R.; Fritzen, A. M.; Larsen, E. L.; Karstoft, K.; Poulsen, H. E.; Morville, T.; Sahl, R. E.; Helge, J. W.; Lund, J.; Falk, S.; Lyngbaek, M.; Ellingsgaard, H.; Pedersen, B. K.; Lu, W.; Finan, B.; Jorgensen, S. B.; Seeley, R. J.; Kleinert, M.; Kiens, B.; Richter, E. A.; Clemmensen, C.
10.1101/2020.10.23.352864 — physiology — Posted on 2020-10-24
1052 Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer
Baca, S. C.; Takeda, D. Y.; Seo, J.-H.; Hwang, J.; Ku, S. Y.; Arafeh, R.; Arnoff, T.; Agarwal, S.; Bell, C.; O'Connor, E.; Qiu, X.; Abu Alaiwi, S.; Corona, R. I.; Fonseca, M. A. S.; Giambartolomei, C.; Cejas, P.; Lim, K.; He, M.; Sheahan, A.; Nassar, A.; Berchuck, J. E.; Brown, L.; Nguyen, H. M.; Coleman, I. M.; Kaipainen, A.; De Sarkar, N.; Nelson, P. S.; Morrissey, C.; Korthauer, K.; Pomerantz, M. M.; Ellis, L.; Pasaniuc, B.; Lawrenson, K.; Kelly, K.; Zoubeidi, A.; Hahn, W. C.; Beltran, H.; Long, H. W.; Brown, M.; Corey, E.; Freedman, M. L.
10.1101/2020.10.23.350793 — cancer biology — Posted on 2020-10-24
1055 Speciation in the face of gene flow within the toothed whale superfamily Delphinoidea
Westbury, M. V.; Cabrera, A. A.; Rey-Iglesia, A.; De Cahsan, B.; Hartmann, S.; Lorenzen, E. D.
10.1101/2020.10.23.352286 — evolutionary biology — Posted on 2020-10-24
1056 Targeting CSF-1 ameliorates experimental autoimmune encephalomyelitis by depleting inflammatory monocytes and microglia in the central nervous system without affecting quiescent microglia.
Hwang, D.; Ishiwaka, L. L. W.; Boehm, A.; Sahin, Z.; Casella, G.; Jang, S.; Seyedsadr, M.; Gonzalez, M. V.; Garifallou, J. P.; Hakonarson, H.; Zhang, G.-X.; Rostami, A.; Ciric, B.
10.1101/2020.10.23.352534 — immunology — Posted on 2020-10-24
1058 Analysis of the Immune Response to Sciatic Nerve Injury Identifies Efferocytosis as a Key Mechanism of Nerve Debridement
Kalinski, A. L.; Yoon, C.; Huffman, L. D.; Duncker, P. C.; Kohen, R.; Passino, R.; Hafner, H.; Johnson, C.; Kawaguchi, R.; Carbajal, K. S.; Jara, J. S.; Hollis, E.; Segal, B.; Giger, R. J.
10.1101/2020.10.23.352872 — neuroscience — Posted on 2020-10-24
1061 SRF-MYOCD axis is the targetable driver of a well differentiated aggressive subtype of leiomyosarcomas
Darbo, E.; Perot, G.; Darmusey, L.; Le Guellec, S.; Leroy, L.; Gaston, L.; Desplat, N.; Thebault, N.; Merle, C.; Rochaix, P.; Valentin, T.; Ferron, G.; Chevreau, C.; Bui, B.; Stoeckle, E.; Ranchere-Vince, D.; Meeus, P.; Terrier, P.; Piperno-Neumann, S.; Colin, F.; De Pinieux, G.; Duffaud, F.; Coindre, J.-M.; Blay, J.-Y.; Chibon, F.
10.1101/2020.10.23.352336 — cancer biology — Posted on 2020-10-24
1065 Mesoscale phase separation of chromatin in the nucleus
Bajpai, G.; Amiad-Pavlov, D.; Lorber, D.; Volk, T.; Safran, S.
10.1101/2020.10.23.338079 — biophysics — Posted on 2020-10-24
1067 One pathway, two cyclic pentapeptides: heterologous expression of BE-18257 A-C and pentaminomycins A-E from Streptomyces cacaoi CA-170360
Roman-Hurtado, F.; Sanchez-Hidalgo, M.; Martin, J.; Ortiz-Lopez, F. J.; Carretero-Molina, D.; Reyes, F.; Genilloud, O.
10.1101/2020.10.23.352575 — molecular biology — Posted on 2020-10-24
1068 Biomolecular models of EPI-X4 binding to CXCR4 allow the rational optimization of peptides with therapeutic potential
Sokkar, P.; Harms, M.; Stuerzel, C. M.; Gilg, A.; Kizilsavas, G.; Raasholm, M.; Preising, N.; Wagner, M.; Staendker, L.; Weidinger, G.; Muench, J.; Sanchez-Garcia,, E.
10.1101/2020.10.23.352708 — molecular biology — Posted on 2020-10-24
1071 Reconstitution of the host holobiont in germ-free rats acutely increases bone growth and affects marrow cellular content
Czernik, P. J.; Golonka, R. M.; Chakraborty, S.; Yeoh, B. S.; Abokor, A.; Saha, P.; Yeo, J. Y.; Mell, B.; Cheng, X.; Baroi, S.; Joe, B.; Vijay-Kumar, M.; Lecka-Czernik, B.
10.1101/2020.07.15.201657 — physiology — Posted on 2020-10-24
1072 Biogenesis of NDUFS3-less complex I indicates TMEM126A/OPA7 as an assembly factor of the ND4-module
D'Angelo, L.; Astro, E.; De Luise, M.; Kurelac, I.; Umesh-Ganesh, N.; Ding, S.; Fearnley, I. M.; Zeviani, M.; Gasparre, G.; Porcelli, A. M.; Fernandez-Vizarra, E.; Iommarini, L.
10.1101/2020.10.22.350587 — biochemistry — Posted on 2020-10-23
1073 MITF Isoforms- Insights from an RNA-Seq study
Kirty, K.; Sigurdsson, S.; Gudjonsson, T.; Einarsdottir, B. O.; Sigurdsson, S.
10.1101/2020.10.22.351031 — genomics — Posted on 2020-10-24
1074 Human mobility at Tell Atchana (Alalakh) during the 2nd millennium BC: integration of isotopic and genomic evidence
Ingman, T.; Eisenmann, S.; Skourtanioti, E.; Akar, M.; Ilgner, J.; Gnecchi Ruscone, G. A.; le Roux, P.; Shafiq, R.; Neumann, G. U.; Keller, M.; Freund, C.; Marzo, S.; Lucas, M.; Krause, J.; Roberts, P.; Yener, K. A.; Stockhammer, P. W.
10.1101/2020.10.23.351882 — genetics — Posted on 2020-10-23
1075 FUNGI DIVERSITY IN THE RHIZOSPHERE OF Aspilia pruliseta Schweif . ext Schweif IN THE SEMI-ARID EASTERN KENYA
MUCHOKA, J.; Njiru, D. M.; Nthakanio, P. N.; Mbugua, P. K.; Njeru, E. M.; Ghilamicael, A. M.; Iguna, M. M.
10.1101/2020.10.23.351908 — ecology — Posted on 2020-10-23
1076 Characterization and variation of bacterial and fungal communities from the sapwood of Apulian olive varieties with different susceptibility to Xylella fastidiosa
Hanani, A.; Valentini, F.; Cavallo, G.; Sanzani, S. M.; Santoro, F.; Minutillo, S. A.; Gallo, M.; El Moujabber, M.; D'Onghia, A. M.; Davino, S. W.
10.1101/2020.10.23.351890 — microbiology — Posted on 2020-10-23
1077 Rapid evolution of enhanced Zika virus virulence during direct vertebrate transmission chains
Riemersma, K. K.; Jaeger, A. S.; Crooks, C. M.; Braun, K. M.; Weger-Lucarelli, J.; Ebel, G. D.; Friedrich, T. C.; Aliota, M. T.
10.1101/2020.10.23.353003 — microbiology — Posted on 2020-10-23
1082 A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex
Chatrikhi, R.; Feeney, C. F.; Pulvino, M. J.; Alachouzos, G.; MacRae, A. J.; Falls, Z.; Rai, S.; Brennessel, W. W.; Jenkins, J. L.; Walter, M. J.; Graubert, T. A.; Samudrala, R.; Jurica, M. S.; Frontier, A. J.; Kielkopf, C. L.
10.1101/2020.09.28.317727 — biochemistry — Posted on 2020-10-23
1085 Restructuring of genomic provinces of surface ocean plankton under climate change
Fremont, P.; Gehlen, M.; Vrac, M.; Leconte, J.; Wincker, P.; Iudicone, D.; Jaillon, O.
10.1101/2020.10.20.347237 — ecology — Posted on 2020-10-23
1086 Nutrient Export and Periphyton Biomass in a Stream-Lake Basin from the Patagonian Andean Region
Sosnovsky, A.; Lallement, M. E.; Rechencq, M.; Fernandez, M. V.; Zattara, E. E.; Feijoo, C. S.
10.1101/2020.09.07.284893 — ecology — Posted on 2020-10-23
1087 Concerted action of kinesins KIF5B and KIF13B promotes efficient secretory vesicle transport to microtubule plus ends
Serra-Marques, A.; Martin, M.; Katrukha, E. A.; Grigoriev, I.; Peeters, C. A. E.; Liu, Q.; Hooikaas, P. J.; Yao, Y.; Solianova, V.; Smal, I.; Pedersen, L. B.; Meijering, E.; Kapitein, L. C.; Akhmanova, A.
10.1101/2020.04.06.027862 — cell biology — Posted on 2020-10-23
1089 Viral mimicry of p65/RelA transactivation domain to inhibit NF-κB activation
Dutra Albarnaz, J.; Ren, H.; Abreu Torres, A.; Shmeleva, E. V.; Melo, C. A.; Bannister, A. J.; Smith, G. L.
10.1101/2020.10.23.353060 — microbiology — Posted on 2020-10-23
1090 Differences in the gut microbiomes of distinct ethnicities within the same geographic area are linked to host metabolic health
Ang, Q. Y.; Alba, D. L.; Upadhyay, V.; Bisanz, J. E.; Cai, J.; Lee, H. L.; Barajas, E.; Wei, G.; Patterson, A. D.; Koliwad, S. K.; Turnbaugh, P. J.
10.1101/2020.10.23.352807 — microbiology — Posted on 2020-10-23
1091 Performance and impact of using a rapid molecular test to detect Chlamydia trachomatis and Neisseria gonorrhoeae in women suspected of having pelvic inflammatory disease
Vergara, A.; MUNROS, J.; BATALLER, E.; RESTOVIC, G.; GARCIA-LORENZO, B.; ALVAREZ-MARTINEZ, M. J.; MIRA, A.; CARMONA, F.; VILA, J.; BOSCH, J.
10.1101/2020.10.23.351825 — microbiology — Posted on 2020-10-23
1098 Mitochondrial ATP Synthase Trafficking along Microtubules to Cell Surface Depends on KIF5B and DRP1
Chang, Y.-W.; Yang, T. T.; Chen, M.-C.; Liaw, Y.-g.; Yin, C.-F.; Huang, T.-Y.; Hou, J.-T.; Hung, Y.-H.; Hsu, C.-L.; Huang, H.-C.; Juan, H.-F.
10.1101/2020.10.23.352385 — systems biology — Posted on 2020-10-23
1100 The mechanism of motor inhibition by microtubule-associated proteins
Ferro, L. S.; Eshun-Wilson, L.; Golcuk, M.; Fernandes, J.; Huijben, T.; Gerber, E.; Jack, A.; Costa, K.; Gur, M.; Feng, Q.; Nogales, E.; Yildiz, A.
10.1101/2020.10.22.351346 — biophysics — Posted on 2020-10-23
1104 Multitrait genetic-phenotype associations to connect disease variants and biological mechanisms
Julienne, H.; Laville, V.; McCaw, Z. R.; He, Z.; Guillemot, V.; Lasry, C.; Ziyatdinov, A.; Vaysse, A.; Lechat, P.; Menager, H.; Le Goff, W.; Dube, M.-P.; Kraft, P.; Ionita-Laza, I.; Vilhjalmsson, B. J.; Aschard, H.
10.1101/2020.06.26.172999 — genetics — Posted on 2020-10-23
1105 Protein hyperacylation links mitochondrial dysfunction with nuclear organization
Smestad, J. A.; McCauley, M.; Amato, M.; Xiong, Y.; Liu, J.; Sin, Y.-C.; Ellingson, J.; Chen, Y.; Al Khazal, F.; Wilbanks, B.; Lee, J.-H.; Ordog, T.; Rouzina, I.; Williams, M. C.; Locasale, J.; Maher, L. J.
10.1101/2020.10.23.350892 — cell biology — Posted on 2020-10-23
1107 Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules
Shams, A.; Higgins, S. A.; Fellmann, C.; Laughlin, T. G.; Oakes, B. L.; Lew, R.; Lukarska, M.; Arnold, M.; Staahl, B.; Doudna, J. A.; Savage, D. F.
10.1101/2020.10.19.344077 — molecular biology — Posted on 2020-10-23
1108 The specific features of the developing T cell compartment of the neonatal lung are a determinant of respiratory syncytial virus immunopathogenesis
Demoulins, T.; Bruegger, M.; Zumhehr, B.; Oliveira Esteves, B.; Mehinagic, K.; Fahmi, A.; Borcard, L.; Taddeo, A.; Posthaus, H.; Benarafa, C.; Ruggli, N.; Alves, M. P.
10.1101/2020.08.14.250829 — immunology — Posted on 2020-10-23
1109 Cortical propagation as a biomarker for recovery after stroke
Cecchini, G.; Scaglione, A.; Allegra Mascaro, A. L.; Checcucci, C.; Conti, E.; Adam, I.; Fanelli, D.; Livi, R.; Pavone, F. S.; Kreuz, T.
10.1101/2020.07.10.197509 — neuroscience — Posted on 2020-10-23
1110 A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions
Rodriguez de los Santos, M.; Rivalan, M.; David, F. S.; Stumpf, A.; Pitsch, J.; Tsortouktzidis, D.; Moreno Velasquez, L.; Voigt, A.; Schilling, K.; Mattei, D.; Long, M.; Vogt, G.; Knaus, A.; Fischer-Zirnsak, B.; Wittler, L.; Timmermann, B.; Robinson, P. N.; Horn, D.; Mundlos, S.; Kornak, U.; Becker, A.; Schmitz, D.; Winter, Y.; Krawitz, P. M.
10.1101/2020.04.20.050591 — neuroscience — Posted on 2020-10-23
1113 Ultrasound neuromodulation through nanobubble-actuated sonogenetics
Hou, X.; Qiu, Z.; Kala, S.; Guo, J.; Zhu, T.; Wong, K. F.; Zhu, J.; Xian, Q.; Yang, M.; Sun, L.
10.1101/2020.10.21.348870 — neuroscience — Posted on 2020-10-23
1114 BrainGNN: Interpretable Brain Graph Neural Network for fMRI Analysis
Li, X.; Zhou, Y.; Zhang, M.; Dvornek, N.; Gao, S.; Gu, S.; Scheinost, D.; Staib, L.; Ventola, P.; Duncan, J.
10.1101/2020.05.16.100057 — neuroscience — Posted on 2020-10-23
1115 Autophagy is required for lipid homeostasis during dark-induced senescence in Arabidopsis
Barros, J. A.; Magen, S.; Lapidot-Cohen, T.; Rosental, L.; Brotman, Y.; Araujo, W. L.; Avin-Wittenberg, T.
10.1101/2020.08.10.245092 — plant biology — Posted on 2020-10-23
1116 CECR2 Drives Breast Cancer Metastasis by Suppressing Macrophage Inflammatory Responses
Zhang, M.; Liu, Z.; Aoshima, K.; Zhang, Y.; An, Y.; Aoshima, A.; Chan, L. H.; Lang, S.; Sun, H.; Tang, Z.; Rutter, S.; Booth, C. J.; Bossuyt, V.; Chen, X.; Morrow, J.; Pusztai, L.; Rimm, D.; Yin, M.; Yan, Q.
10.1101/2020.09.10.291799 — cancer biology — Posted on 2020-10-23
1117 Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19
Le, B. L.; Andreoletti, G.; Oskotsky, T.; Vallejo-Gracia, A.; Rosales, R.; Yu, K. Z.; Kosti, I.; Leon, K. E.; Bunis, D. G.; Li, C.; Kumar, G. R.; White, K. M.; Garcia-Sastre, A. E.; Ott, M.; Sirota, M.
10.1101/2020.10.23.352666 — bioinformatics — Posted on 2020-10-23
1122 Identifying flow modules in ecological networks using Infomap
Farage, C.; Edler, D.; Eklöf, A.; Rosvall, M.; Pilosof, S.
10.1101/2020.04.14.040519 — ecology — Posted on 2020-10-23
1123 Rewiring of peatland plant-microbe networks outpaces species turnover
Robroek, B. J.; Marti, M.; Svensson, B. H.; Dumont, M. G.; Veraart, A. J.; Jassey, V. E.
10.1101/2020.05.12.090274 — ecology — Posted on 2020-10-23
1124 Molecular estimation of neurodegeneration pseudotime in older brains
Mukherjee, S.; Heath, L.; Preuss, C.; Jayadev, S.; Garden, G. A.; Greenwood, A. K.; Sieberts, S. K.; De Jager, P. L.; Ertekin-Taner, N.; Carter, G. W.; Mangravite, L. M.; Logsdon, B.
10.1101/686824 — neuroscience — Posted on 2020-10-23
1129 Functional Microswitches of Mammalian G Protein-Coupled Bitter-Taste Receptors
Topin, J.; Bouysset, C.; Kim, Y.; Rhyu, M.; Fiorucci, S.; Golebiowski, J.
10.1101/2020.10.23.348706 — bioinformatics — Posted on 2020-10-23
1136 Trehalose and α-glucan mediate distinct abiotic stress responses in Pseudomonas aeruginosa
Woodcock, S. D.; Syson, K.; Little, R. H.; Sifouna, D.; Brown, J. K. M.; Bornemann, S.; Malone, J. G.
10.1101/2020.10.23.351924 — microbiology — Posted on 2020-10-23
1137 Efficient long-range conduction in cable bacteria through nickel protein wires
Boschker, H. T. S.; Cook, P. L. M.; Polerecky, L.; Thiruvallur Eachambadi, R.; Lozano, H.; Hidalgo-Martinez, S.; Khalenkow, D.; Spampinato, V.; Claes, N.; Kundu, P.; Wang, D.; Bals, S.; Sand, K. K.; Cavezza, F.; Hauffman, T.; Tataru Bjerg, J.; Skirtach, A. G.; Kochan, K.; McKee, M.; Wood, B.; Bedolla, D.; Gianoncelli, A.; Geerlings, N. M. J.; Van Gerven, N.; Remaut, H.; Geelhoed, J. S.; Millan-Solsona, R.; Fumagalli, L.; Nielsen, L.-P.; Franquet, A.; Manca, J. V.; Gomila, G.; Meysman, F. J. R.
10.1101/2020.10.23.351973 — microbiology — Posted on 2020-10-23
1138 Single cell RNA-seq reveals immunosuppressive gastric stem-like cancer cells as a poor prognostic factor
Lee, H. K.; Ang, K. S.; Chevrier, M.; Goh, M.; Ling, J.; Koh, V.; Zhang, X.; Tan, J. C.; Lee, N.; Erdal Irac, S.; Lim, Z. M.; Lum, J.; Tay, A.; Antoine Dutertre, C.; Tang, C.; Wong, C.; Lau, M. C.; Lim, C. J.; Chuah, S. W. J.; Lim, S.; Yeong, J. P. S.; Chew, V.; Larbi, A.; Singhal, A.; Poidinger, M.; Ng, M. C. H.; Wu Howland, S.; Tan, P.; Ginhoux, F.; So, J.; Yong, W. P.; Chen, J.
10.1101/2020.10.23.351726 — immunology — Posted on 2020-10-23
1139 In vivo visualization of propagating α-synuclein pathologies in mouse and marmoset models by a bimodal imaging probe, C05-05
Ono, M.; Takahashi, M.; Shimozawa, A.; Fujinaga, M.; Mori, W.; Nagai, Y.; Mimura, K.; Minamihisamatsu, T.; Uchida, S.; Shimojo, M.; Takado, Y.; Takuwa, H.; Sahara, N.; Zhang, M.-R.; Minamimoto, T.; Hasegawa, M.; Higuchi, M.
10.1101/2020.10.23.349860 — neuroscience — Posted on 2020-10-23
1144 Goblet cell LRRC26 regulates BK channel activation and protects against colitis in mice
Gonzalez-Perez, V. M.; Martinez-Espinosa, P. L.; Sala-Rabanal, M.; Bharadwaj, N.; Xia, X.; Chen, A. C.; Alvarado, D.; Gustafsson, J. K.; Hu, H.; Ciorba, M. A.; Lingle, C. J.
10.1101/2020.10.23.341396 — physiology — Posted on 2020-10-23
1145 Establishment of a simplified preparation method for single-nucleus RNA-sequencing and its application to long-term frozen tumor tissues
Ernst, K. F.; Okonechnikov, K.; Bageritz, J.; Mallm, J.-P.; Wittmann, A.; Maass, K. K.; Leible, S.; Boutros, M.; Pfister, S. M.; Zuckermann, M.; Jones, D. T. W.
10.1101/2020.10.23.351809 — cancer biology — Posted on 2020-10-23
1148 An extended reconstruction of human gut microbiota metabolism for personalized nutrition
Blasco, T.; Perez-Burillo, S.; Balzerani, F.; Lerma, A.; Hinojosa-Nogueira, D.; Pastoriza, S.; Gosalbes, M. J.; Jimenez-Hernandez, N.; Francino, M. P.; Rufian-Henares, J. A.; Apaolaza, I.; Planes, F. J.
10.1101/2020.10.23.350462 — bioinformatics — Posted on 2020-10-23
1153 Spontaneous emergence of azithromycin resistance in independent lineages of Salmonella Typhi in Northern India
Carey, M. E.; Jain, R.; Yousuf, M.; Maes, M.; Dyson, Z. A.; Thu, T. N. H.; Nguyen, T. N. T.; Dan, T. H. N.; Nguyen, Q. N. P.; Mahindroo, J.; Pham, D. T.; Sandha, K. S.; Baker, S.; Taneja, N.
10.1101/2020.10.23.351957 — genomics — Posted on 2020-10-23
1159 B LYMPHOCYTES, BUT NOT DENDRITIC CELLS, EFFICIENTLY HIV-1 TRANS-INFECT NAÏVE CD4+ T CELLS: IMPLICATIONS FOR THE VIRAL RESERVOIR
Gerberick, A.; DeLucia, D. C.; Piazza, P. A.; Alaoui-El-Azher, M.; Rinaldo, C. R.; Sluis-Cremer, N.; Rappocciolo, G.
10.1101/2020.10.22.351627 — microbiology — Posted on 2020-10-23
1164 A novel method for measuring phenotypic colistin resistance in Escherichia coli populations from chicken flocks
Nguyen, N. T.; Phuong Yen, N. T.; Ky Thien, N. V.; Van Cuong, N.; Kiet, B. T.; Campbell, J. I.; Thwaites, G.; Baker, S.; Geskus, R. B.; Carrique-Mas, J. J.
10.1101/2020.10.22.351577 — microbiology — Posted on 2020-10-23
1171 Integration, exploration, and analysis of high-dimensional single-cell cytometry data using Spectre
Ashhurst, T. M.; Marsh-Wakefield, F.; Putri, G. H.; Spiteri, A. G.; Shinko, D.; Read, M. N.; Smith, A. L.; King, N. J. C.
10.1101/2020.10.22.349563 — immunology — Posted on 2020-10-23
1172 Amplification of potential thermogenetic mechanisms in cetacean brains
Manger, P. R.; Patzke, N.; Spocter, M.; Bhagwandin, A.; Karlsson, K.; Bertelsen, M.; Alagaili, A.; Bennett, N.; Mohammed, O.; Herculano-Houzel, S.; Hof, P.; Fuxe, K.
10.1101/2020.10.23.352138 — neuroscience — Posted on 2020-10-23
1177 The Oscillatory Effects of Rhythmic Median Nerve Stimulation
Houlgreave, M. S.; Morera Maiquez, B.; Brookes, M. J.; Jackson, S. R.
10.1101/2020.10.23.348268 — neuroscience — Posted on 2020-10-23
1178 Patient iPSC-astrocytes show transcriptional and functional dysregulation in schizophrenia
Koskuvi, M.; Lehtonen, S.; Trontti, K.; Keuters, M.; Wu, Y. C.; Koivisto, H.; Ludwig, A.; Plotnikova, L.; Virtanen, P. L. J.; Räsänen, N.; Kaipainen, S.; Hyötyläinen, I.; Dhungana, H.; Giniatullina, R.; Ojansuu, I.; Vaurio, O.; Cannon, T. D.; Lönnqvist, J.; Therman, S.; Suvisaari, J.; Kaprio, J.; Lähteenvuo, M.; Tohka, J.; Giniatullin, R.; Rivera, C.; Hovatta, I.; Tanila, H.; Tiihonen, J.; Koistinaho, J.
10.1101/2020.10.23.350413 — neuroscience — Posted on 2020-10-23
1182 Mitochondrial ATP Synthase Trafficking along Microtubules to Cell Surface Depends on KIF5B and DRP1
Chang, Y.-W.; Yang, T. T.; Chen, M.-C.; Liaw, Y.-g.; Yin, C.-F.; Huang, T.-Y.; Hou, J.-T.; Hung, Y.-H.; Hsu, C.-L.; Huang, H.-C.; Juan, H.-F.
10.1101/2020.10.23.352385 — systems biology — Posted on 2020-10-23
1183 A damaged-informed lung model for ventilator waveforms
Agrawal, D. K.; Smith, B. J.; Sottile, P. D.; Albers, D. J.
10.1101/2020.10.23.351320 — physiology — Posted on 2020-10-23
1184 Transcriptional silencing of ALDH2 in acute myeloid leukemia confers a dependency on Fanconi anemia proteins
Yang, Z.; Wei, Y.; Wu, X. S.; Iyer, S. V.; Jung, M.; Adelman, E. R.; Klingbeil, O.; Kramer, M.; Demerdash, O. E.; Chang, K.; Goodwin, S.; Hodges, E.; McCombie, W. R.; Figueroa, M. E.; Smogorzewska, A.; Vakoc, C. R.
10.1101/2020.10.23.352070 — cancer biology — Posted on 2020-10-23
1185 ATRX alteration contributes to tumor growth and immune escape in pleomorphic sarcomas
Darmusey, L.; Perot, G.; Thebault, N.; Le Guellec, S.; Desplat, N.; Gaston, L.; Delespaul, L.; Lesluyes, T.; Darbo, E.; Gomez-Brouchet, A.; Richard, E.; Baud, J.; Leroy, L.; Coindre, J. M.; Blay, J.-Y.; Chibon, F.
10.1101/2020.10.23.352112 — cancer biology — Posted on 2020-10-23
1189 NUPR1 protects liver from lipotoxic injury by improving the endoplasmic reticulum stress response
Borrello, M. T.; Emma, M.; Listi, A.; Rubis, M.; Coslet, S.; Augello, G.; Cusimano, A.; Cabibi, D.; Porcasi, R.; Giannitrapani, L.; Soresi, M.; Pantuso, G.; Blyth, K.; Montalto, G.; Pin, C. L.; Cervello, M.; Iovanna, J. L.
10.1101/2020.10.23.350652 — cell biology — Posted on 2020-10-23
1190 A Wnt5a-Cdc42 axis controls aging and rejuvenation of hair-follicle stem cells
Tiwari, R. L.; Mishra, P.; Martin, N.; George, N. O.; Sakk, V.; Soller, K.; Nalapareddy, K.; Nattamai, K.; Kochanek, K. S.; Florian, M. C.; Geiger, H.
10.1101/2020.10.22.351544 — cell biology — Posted on 2020-10-23
1191 SARS-CoV-2 Nucleocapsid protein attenuates stress granule formation and alters gene expression via direct interaction with host mRNAs
Nabeel-Shah, S.; Lee, H.; Ahmed, N.; Marcon, E.; Farhangmehr, S.; Pu, S.; Burke, G. L.; Ashraf, K.; Wei, H.; Zhong, G.; Tang, H.; Yang, J.; Blencowe, B.; Zhang, Z.; Greenblatt, J. F.
10.1101/2020.10.23.342113 — molecular biology — Posted on 2020-10-23
1192 Spike glycoprotein and host cell determinants of SARS-CoV-2 entry and cytopathic effects
Nguyen, H. T.; Zhang, S.; Wang, Q.; Anang, S.; Wang, J.; Ding, H.; Kappes, J. C.; Sodroski, J. G.
10.1101/2020.10.22.351569 — microbiology — Posted on 2020-10-23
1193 Transferrin receptor is another receptor for SARS-CoV-2 entry
Tang, X.; Yang, M.; Duan, Z.; Liao, Z.; Liu, L.; Cheng, R.; Fang, M.; Wang, G.; Liu, H.; Xu, J.; Kamau, P. M.; Zhang, Z.; Yang, L.; Zhao, X.; Peng, X.; Lai, R.
10.1101/2020.10.23.350348 — microbiology — Posted on 2020-10-23
1196 Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine
Jangra, S.; De Vrieze, J.; Choi, A.; Rathnasinghe, R.; Laghlali, G.; Uvyn, A.; Van Herck, S.; Nuhn, L.; Deswarte, K.; Zhong, Z.; Sanders, N.; Lienenklaus, S.; David, S.; Strohmeier, S.; Amanat, F.; Krammer, F.; Hammad, H.; Lambrecht, B. N.; Coughlan, L.; Garcia-Sastre, A.; De Geest, B. G.; Schotsaert, M.
10.1101/2020.10.23.344085 — microbiology — Posted on 2020-10-23
1199 De novo design of transmembrane beta-barrels
Vorobieva, A. A.; White, P.; Liang, B.; Horne, J. E.; Bera, A. K.; Chow, C. M.; Gerben, S. R.; Marx, S.; Kang, A.; Stiving, A. Q.; Harvey, S. R.; Marx, D. C.; Khan, N.; Fleming, K. G.; Wysocki, V. H.; Brockwell, D. J.; Tamm, L. K.; Radford, S. E.; Baker, D.
10.1101/2020.10.22.346965 — synthetic biology — Posted on 2020-10-23
1200 PI3K inhibition as a novel therapeutic strategy for neoadjuvant chemoradiotherapy resistant oesophageal adenocarcinoma
Edge, S. D.; Renard, I.; Pyne, E.; Moody, H.; Roy, R.; Beavis, A. W.; Archibald, S. J.; Cawthorne, C. J.; Maher, S. G.; Pires, I. M.
10.1101/2020.10.23.351981 — cancer biology — Posted on 2020-10-23
1201 The mechanism of motor inhibition by microtubule-associated proteins
Ferro, L. S.; Eshun-Wilson, L.; Golcuk, M.; Fernandes, J.; Huijben, T.; Gerber, E.; Jack, A.; Costa, K.; Gur, M.; Feng, Q.; Nogales, E.; Yildiz, A.
10.1101/2020.10.22.351346 — biophysics — Posted on 2020-10-23
1209 Cell group analysis reveals changes in upper-layer neurons associated with schizophrenia
Dai, R.; Chen, L.; Liu, S.; Chen, Y.; Jiang, Y.; Dai, J.; Wang, Q.; Kuney, L.; Kopp, R.; Yu, G.; Wang, Y.; Chen, C.; Liu, C.
10.1101/2020.10.22.351213 — genomics — Posted on 2020-10-23
1211 SARS-CoV-2 receptor Angiotensin I-Converting Enzyme type 2 (ACE2) is expressed in human pancreatic β-cells and in the human pancreas microvasculature
Fignani, D.; Licata, G.; Brusco, N.; Nigi, L.; Grieco, G. E.; Marselli, L.; Overbergh, L.; Gysemans, C.; Colli, M. L.; Marchetti, P.; Mathieu, C.; Eizirik, D. L.; Sebastiani, G.; Dotta, F.
10.1101/2020.07.23.208041 — cell biology — Posted on 2020-10-23
1213 A Bacterial Signaling Network Controls Antibiotic Resistance by Regulating Anaplerosis of 2-oxoglutarate
Hurst, M. N.; Beebout, C. J.; Mersfelder, R.; Hollingsworth, A. N.; Guckes, K. R.; Bermudez, T. A.; Floyd, K. A.; Reasoner, S.; Williams, D. C.; Hadjifrangiskou, M.
10.1101/2020.10.22.351270 — microbiology — Posted on 2020-10-23
1214 Adenosine diphosphate contributes to wound healing in diabetic mice through P2Y1 and P2Y12 receptors activation
Borges, P. A.; Waclawiak, I.; Georgii, J. L.; Barros, J. F.; Fraga-Junior, V. S.; Lemos, F. S.; Russo-Abrahao, T.; Saraiva, E. M.; Takiya, C. M.; Coutinho-Silva, R.; Penido, C.; Mermelstein, C.; Meyer-Fernandes, J. R.; Canto, F.; Neves, J. S.; Melo, P. A.; Canetti, C.; Benjamim, C. F.
10.1101/2020.10.22.350785 — immunology — Posted on 2020-10-23
1215 Tolerogenic Dendritic Cells Shape a Transmissible Gut Microbiota that Protects from Metabolic Diseases
Lecuyer, E.; Le Roy, T.; Gestin, A.; Lacombe, A.; Philippe, C.; Ponnaiah, M.; Hure, J. B.; Fradet, M.; Chou, F.; Boudebbouze, S.; Huby, T.; Gautier, E.; Rhimi, M.; Maguin, E.; Kapel, N.; Gerard, P.; Venteclef, N.; Garlatti, M.; Chassaing, B.; Lesnik, P.
10.1101/2020.10.22.350033 — immunology — Posted on 2020-10-23
1216 Training-induced prefrontal neuronal changes transfer between tasks
Tang, H.; Riley, M. R.; Singh, B.; Qi, X.; Blake, D. T.; Constantinidis, C.
10.1101/2020.10.22.351197 — neuroscience — Posted on 2020-10-23
1218 Comprehensive enhancer-target gene assignments improve gene set level interpretation of genome-wide regulatory data
Qin, T.; Lee, C.; Cavalcante, R.; Orchard, P.; Yao, H.; Zhang, H.; Wang, S.; Patil, S.; Boyle, A. P.; Sartor, M. A.
10.1101/2020.10.22.351049 — bioinformatics — Posted on 2020-10-23
1219 Multivariate genome-wide association study identifies 1735 unique genetic loci associated with cortical morphology.
Shadrin, A. A.; Kaufmann, T.; van der Meer, D.; Palmer, C. E.; Makowski, C.; Loughnan, R. J.; Jernigan, T. L.; Seibert, T. M.; Hagler, D. J.; Smeland, O. B.; Chu, Y.; Lin, A.; Cheng, W.; Hindley, G.; Thompson, W. K.; Fan, C. C.; Holland, D.; Westlye, L. T.; Frei, O.; Andreassen, O. A.; Dale, A. M.
10.1101/2020.10.22.350298 — genetics — Posted on 2020-10-23
1220 MLS3: A New Type of Multilevel Selection
Jones, C. T.; Doolittle, W. F.; Susko, E.; Meynell, L.; Neto, C.; Lenton, T. M.; Bielawski, J. P.
10.1101/2020.10.22.350272 — evolutionary biology — Posted on 2020-10-23
1221 Object-Attribute Biclustering for Elimination of Missing Genotypes in Ischemic Stroke Genome-Wide Data
Ignatov, D. I.; Khvorykh, G. V.; Khrunin, A. V.; Nikolic, S.; Shaban, M.; Petrova, E. A.; Koltsova, E. A.; Takelait, F.; Egurnov, D.
10.1101/2020.10.22.349910 — bioinformatics — Posted on 2020-10-23
1222 Altered food habits? Understanding the feeding preference of free-ranging Grey langur (Semnopithecus entellus) within an urban settlement.
Dasgupta, D.; Banerjee, A.; Karar, R.; Banerjee, D.; Mitra, S.; Sardar, P.; Karmakar, S.; Bhattacharya, A.; Ghosh, S.; Bhattacharjee, P.; Paul, M.
10.1101/2020.10.22.350926 — animal behavior and cognition — Posted on 2020-10-23
1223 Discovering the drivers of clonal hematopoiesis
Pich, O.; Reyes-Salazar, I.; Gonzalez-Perez, A.; Lopez-Bigas, N.
10.1101/2020.10.22.350140 — genomics — Posted on 2020-10-23
1224 A new method to accurately identify single nucleotide variants using small FFPE breast samples.
Fortunato, A.; Mallo Adan, D.; Rupp, S. M.; King, L.; Hardman, T.; Lo, J.; Hall, A.; Marks, J. R.; Hwang, E. S.; Maley, C. C.
10.1101/2020.10.22.350983 — genomics — Posted on 2020-10-23
1236 Cardiovascular disease risk factors induce mesenchymal features and senescence in cardiac endothelial cells
Hemanthakumar, K. A.; Fang, S.; Anisimov, A.; Mäyränpää, M. I.; Mervaala, E.; Kivelä, R.
10.1101/2020.10.21.349472 — molecular biology — Posted on 2020-10-23
1238 Hierarchical complexity of the macro-scale neonatal brain
Blesa, M.; Galdi, P.; Cox, S. R.; Sullivan, G.; Stoye, D. Q.; Lamb, G. J.; Quigley, A. J.; Thrippleton, M. J.; Escudero, J.; Bastin, M. E.; Smith, K.; Boardman, J. P.
10.1101/2020.01.16.909150 — neuroscience — Posted on 2020-10-23
1239 KRAS signalling in malignant pleural mesothelioma
Marazioti, A.; Krontira, A.; Pepe, M. A.; Iliopoulou, M.; Wagner, D. E.; Papadaki, H.; Antimisiaris, S. G.; Psallidas, I.; Spella, M.; Lilis, I.; Giopanou, I.; Vreka, M.; Blanquart, C.; Gregoire, M.; Deshayes, S.; Hackl, C. M.; Lamort, A. S.; Koch, I.; Lindner, M.; Hatz, R. A.; Behr, J.; Stathopoulos, G. T.
10.1101/2020.10.22.350850 — physiology — Posted on 2020-10-23
1242 Hippocampal replay of experience at real-world speeds
Denovellis, E. L.; Gillespie, A. K.; Coulter, M. E.; Sosa, M.; Chung, J. E.; Eden, U. T.; Frank, L. M.
10.1101/2020.10.20.347708 — neuroscience — Posted on 2020-10-23
1246 Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction
Condon, K. J.; Orozco, J. M.; Adelmann, C. H.; Spinelli, J. B.; van der Helm, P. W.; Roberts, J. M.; Kunchok, T.; Sabatini, D. M.
10.1101/2020.10.22.351361 — cell biology — Posted on 2020-10-22
1247 Reverse-transcription recombinase-aided amplification assay for H5 subtype avian influenza virus
Wang, K.; Wang, S.; Li, Y.; Jiang, N.; Zhang, F.; Zhuang, Q.; Hou, G.; Jiang, L.; Yu, J.; Yu, X.; Liu, H.; Zhao, C.; Yuan, L.; Huang, B.
10.1101/2020.10.22.350025 — molecular biology — Posted on 2020-10-22
1248 Agency improves working memory and accelerates visual and attentional processing
Loyola-Navarro, R.; Moenne-Loccoz, C.; Vergara, R. C.; Hyafil, A.; Aboitiz, F.; Maldonado, P. E.
10.1101/2020.10.22.350397 — neuroscience — Posted on 2020-10-22
1251 Functional Characterization of fer-ts, a ts- FERONIA Mutant Allele That Alters Root Hair Growth
Kim, D.; Yang, J.; Gu, F.; Park, S.; Combs, J.; Adams, A.; Mayes, H. B.; Nielsen, E.
10.1101/2020.05.27.119891 — plant biology — Posted on 2020-10-22
1252 Role of PIF4 and FLC in controlling flowering time under daily variable temperature profile
Jenkitkonchai, J.; Marriott, P.; Yang, W.; Sriden, N.; Jung, J.-H.; Wigge, P. A.; Charoensawan, V.
10.1101/2020.10.22.348540 — plant biology — Posted on 2020-10-22
1253 Deciphering the Agonist Binding Mechanism to the Adenosine A1 Receptor
Deganutti, G.; Barkan, K.; Preti, B.; Leuenberger, M.; Wall, M.; Frenguelli, B.; Lochner, M.; Ladds, G.; Reynolds, C. A.
10.1101/2020.10.22.350827 — pharmacology and toxicology — Posted on 2020-10-22
1254 Selection of internal references for transcriptomics and RT-qPCR assays in Neurofibromatosis type 1 (NF1) related Schwann cell lines
Gu, Y.-H.; Cui, X.-W.; Ren, J.-Y.; Long, M.-M.; Wang, W.; Wei, C.-J.; Aimaier, R.; Li, Y.-H.; Chung, M.-H.; Gu, B.; Li, Q.-F.; Wang, Z.-C.
10.1101/2020.10.22.350017 — cancer biology — Posted on 2020-10-22
1257 Undaria pinnatifida exudates trigger shifts in seawater chemistry and microbial communities from Atlantic Patagonian coasts
Lozada, M.; Dieguez, M. C.; Garcia, P. E.; Bigatti, G.; Livore, J. P.; Giarratano, E.; Gil, M. N.; Dionisi, H. M.
10.1101/2020.10.21.349233 — microbiology — Posted on 2020-10-22
1261 PTBP1 Regulates Injury Responses and Sensory Pathways in Adult Peripheral Neurons
Alber, S.; Di-Matteo, P.; Zdradzinski, M. D.; Marvaldi, L.; Kawaguchi, R.; Medzihradszky, K. F.; Doron-Mandel, E.; Okladnikov, N.; Rishal, I.; Nevo, R.; Lee, S. J.; Sahoo, P. K.; Burlingame, A. L.; Coppola, G.; Twiss, J. L.; Fainzilber, M.
10.1101/2020.10.22.348631 — neuroscience — Posted on 2020-10-22
1263 MAPK-induced miR-29 targets MAFG and suppresses melanoma development
Vera, O.; Bok, I.; Jasani, N.; Nakamura, K.; Xu, X.; Mecozzi, N.; Angarita, A.; Wang, K.; Tsai, K. Y.; Karreth, F. A.
10.1101/2020.01.27.922153 — cancer biology — Posted on 2020-10-22
1264 Analysis of ovarian transcriptomes reveals thousands of novel genes in the insect vector Rhodnius prolixus
Coelho, V. L.; Brito, T. F. d.; Brito, I. A. d. A.; Cardoso, M. A.; Berni, M. A.; Araujo, H. M. M.; Sammeth, M.; Pane, A.
10.1101/2020.10.22.351072 — bioinformatics — Posted on 2020-10-22
1268 The Histone Chaperone CAF-1 Sustains Myeloid Lineage Identity
Guo, Y.; Ji, F.; Murn, J.; Frankhouser, D.; Blanco, A.; Chiem, C.; Jang, M.; Sadreyev, R.; Rockne, R.; Sykes, D.; Hochedlinger, K.; Cheloufi, S.
10.1101/2020.10.22.350447 — molecular biology — Posted on 2020-10-22
1269 Systematic characterization and genetic interaction analysis of adhesins in Candida albicans virulence
Rosiana, S.; Zhang, L.; Kim, G. H.; Revtovich, A. V.; Sukumaran, A.; Geddes-McAlister, J.; Kirienko, N. V.; Shapiro, R. S.
10.1101/2020.10.22.350991 — microbiology — Posted on 2020-10-22
1271 Unveiling the sensory and interneuronal pathways of the neuroendocrine system in Drosophila
Hückesfeld, S.; Schlegel, P.; Miroschnikow, A.; Schoofs, A.; Zinke, I.; Haubrich, A. N.; Schneider-Mizell, C. M.; Truman, J. W.; Fetter, R. D.; Cardona, A.; Pankratz, M. J.
10.1101/2020.10.22.350306 — neuroscience — Posted on 2020-10-22
1273 Implicit anticipation of probabilistic regularities: Larger CNV emerges for unpredictable events
Kobor, A.; Kardos, Z.; Horvath, K.; Janacsek, K.; Takacs, A.; Csepe, V.; Nemeth, D.
10.1101/2020.08.14.251686 — neuroscience — Posted on 2020-10-22
1275 DNMT3A haploinsufficiency results in behavioral deficits and global epigenomic dysregulation shared across neurodevelopmental disorders
Christian, D. L.; Wu, D. Y.; Martin, J. R.; Moore, J. R.; Liu, Y. R.; Clemens, A. W.; Nettles, S. A.; Kirkland, N. M.; Hill, C. A.; Wozniak, D. F.; Dougherty, J. D.; Gabel, H. W.
10.1101/2020.07.10.195859 — neuroscience — Posted on 2020-10-22
1276 The auxin transporter PIN1 and the cytokinin transporter AZG1 interact to regulate the root stress response
Tessi, T. M.; Shahriari, M.; Maurino, V.; Meissner, E.; Novak, O.; Pasternak, T.; Schumacher, B.; Flubacher, N.; Nautscher, M.; Williams, A.; Kazimierczak, Z.; Strnad, M.; Thumfart, J. O.; Palme, K.; Desimone, M.; Teale, W.
10.1101/2020.10.22.350363 — plant biology — Posted on 2020-10-22
1280 PharmaNet: Pharmaceutical discovery with deep recurrent neural networks.
Ruiz Puentes, P.; Valderrama, N.; Gonzalez, C.; Daza, L.; Munoz-Camargo, C.; Cruz, J. C.; Arbelaez, P.
10.1101/2020.10.21.348441 — bioinformatics — Posted on 2020-10-22
1281 In silico secretome characterization of clinical Mycobacterium abscessus isolates provides insights into antigenic differences
Cornejo-Granados, F.; Kohl, T. A.; Sotomayor, F. V.; Andres, S.; Hernandez-Pando, R.; Hurtado-Ramirez, J. M.; Utpatel, C.; Niemann, S.; Maurer, F. P.; Ochoa-Leyva, A.
10.1101/2020.10.22.349720 — bioinformatics — Posted on 2020-10-22
1282 Configurable Digital Virus Counter on Robust Universal DNA Chips
Seymour, E.; Unlu, N. L.; Carter, E. P.; Connor, J. H.; Unlu, M. S.
10.1101/2020.10.22.350579 — bioengineering — Posted on 2020-10-22
1283 Mammalian Cell Proliferation Requires Noncatalytic Functions of O-GlcNAc Transferase
Levine, Z. G.; Potter, S. C.; Joiner, C. M.; Fei, G. Q.; Nabet, B.; Sonnett, M.; Zachara, N. E.; Paulo, J. A.; Walker, S.
10.1101/2020.10.22.351288 — biochemistry — Posted on 2020-10-22
1285 Molecular determinants for α-tubulin methylation by SETD2
Kearns, S.; Mason, F. M.; Rathmell, W. K.; Park, I. Y.; Walker, C.; Verhey, K. A.; Cianfrocco, M. A.
10.1101/2020.10.21.349365 — biochemistry — Posted on 2020-10-22
1286 A 180 My-old female-specific genome region in sturgeon reveals the oldest known vertebrate sex determining system with undifferentiated sex chromosomes
Kuhl, H.; Guiguen, Y.; Hoehne, C.; Keuz, E.; Klopp, C.; Du, K.; Lopez-Roques, C.; Santidrian Yebra-Pimentel, E.; Ciorpac, M.; Gessner, J.; Holostenco, D.; Kleiner, W.; Kohlmann, K.; Lamatsch, D.; Prokopov, D.; Bestin, A.; Bonpunt, E.; Debeuf, B.; Haffay, P.; Morvezen, R.; Patrice, P.; Suciu, R.; Dirks, R.; Wuertz, S.; Kloas, W.; Schartl, M.; Stoeck, M.
10.1101/2020.10.10.334367 — evolutionary biology — Posted on 2020-10-22
1289 Mitochondrial fission governed by Drp1 regulates exogenous fatty acid usage and storage
Song, J. E.; Alves, T.; Stutz, B.; Sestan-Pesa, M.; Kilian, N.; Diano, S.; Kibbey, R.; Horvath, T.
10.1101/2020.10.17.343616 — cell biology — Posted on 2020-10-22
1290 Naegleria fowleri: protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba
Barrett, K.; Tillery, L.; Goldstein, J.; Lassner, J. W.; Osterhout, B.; Tran, N. L.; Xu, L.; Young, R.; Craig, J.; Chun, I.; Dranow, D. M.; Abendroth, J.; Delker, S. L.; Davies, D. R.; Mayclin, S. J.; Calhoun, B.; Bolejack, M. J.; Staker, B.; Subramanian, S.; Phan, I. Q.; Lorimer, D. D.; Myler, P. J.; Edwards, T. E.; Kyle, D. E.; Rice, C. A.; Morris, J.; Leahy, J. W.; Manetsch, R.; Barrett, L. K.; Smith, C.; Van Voorhis, W.
10.1101/2020.10.20.327296 — molecular biology — Posted on 2020-10-22
1293 Parabacteroides distasonis insulin B:9-23 epitope mimic stimulates insulin specific T-cells and enhances Type 1 Diabetes in NOD mice
Huang, Q.; Chow, I.-T.; Brady, C.; Raisingani, A.; Li, D.; Ostrov, D. A.; Atkinson, M. A.; Kwok, W. W.; Kahn, C. R.; ALTINDIS, E.
10.1101/2020.10.22.350801 — immunology — Posted on 2020-10-22
1294 Lymphatic PD-L1 expression restricts tumor-specific CD8+ T cell responses
Cap, S.; Dihr, M.; Cousin, N.; Tacconi, C.; Detmar, M.; Dieterich, L.
10.1101/2020.10.22.350934 — immunology — Posted on 2020-10-22
1298 Cathepsin D exacerbates SPARC-driven aggressiveness by limited proteolysis in triple-negative breast cancer
Alcaraz, L. B.; Mallavialle, A.; David, T.; Derocq, D.; Delolme, F.; Dieryckx, C.; Boissiere-Michot, F.; Simony-Lafontaine, J.; Du Manoir, S.; Huesgen, P.; Overall, C. M.; Tartare-Deckert, S.; Jacot, W.; Chardes, T.; Guiu, S.; Roger, P.; Reinheckel, T.; Moali, C.; Liaudet-Coopman, E.
10.1101/2020.10.22.350082 — cancer biology — Posted on 2020-10-22
1299 Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking LAIR-collagen interaction
Ramos, M. I. P.; Tian, L.; de Ruiter, E. J.; Song, C.; Paucarmayta, A.; Singh, A.; Elshof, E.; Vijver, S. V.; Shaik, J.; Bosiacki, J.; Cusumano, Z.; Liu, L.; Langermann, S.; Willems, S.; Flies, D.; Meyaard, L.
10.1101/2020.10.21.349480 — cancer biology — Posted on 2020-10-22
1300 LPA/PKD-1 signaling promotes development of arteriolar niche that supports self-renewal of breast cancer stem cells and stemness
Jiang, Y.; Guo, Y.; Hao, J.; Guenter, R.; Lathia, J.; Beck, A. W.; Hattaway, R.; Hurst, D.; Wang, Q. J.; Liu, Y.; Cao, Q.; Krontiras, H.; Chen, H.; Silverstein, R. L.; Ren, B.
10.1101/2020.10.22.351122 — cancer biology — Posted on 2020-10-22
1301 NG2+/Nestin+ mesenchymal stem cells dictate DTC dormancy in the bone marrow through TGFβ2
Nobre, A. R.; Risson, E.; Singh, D. K.; Di Martino, J. S.; Cheung, J. F.; Wang, J.; Johnson, J.; Russnes, H. G.; Bravo-Cordero, J. J.; Birbrair, A.; Naume, B.; Azhar, M.; Frenette, P. S.; Aguirre-Ghiso, J. A.
10.1101/2020.10.22.349514 — cancer biology — Posted on 2020-10-22
1305 Fast 3D printing of large-scale biocompatible hydrogel models
Anandakrishnan, N.; Ye, H.; Guo, Z.; Chen, Z.; Mentkowski, K.; Lang, J. K.; Rajabian, N.; Andreadis, S.; Ma, Z.; Spernyak, J.; Lovell, J. F.; Wang, D.; Xia, J.; Zhou, C.; Zhao, R.
10.1101/2020.10.22.345660 — bioengineering — Posted on 2020-10-22
1306 Biogenesis of NDUFS3-less complex I indicates TMEM126A/OPA7 as an assembly factor of the ND4-module
D'Angelo, L.; Astro, E.; De Luise, M.; Kurelac, I.; Umesh-Ganesh, N.; Ding, S.; Fearnley, I. M.; Zeviani, M.; Gasparre, G.; Porcelli, A. M.; Fernandez-Vizarra, E.; Iommarini, L.
10.1101/2020.10.22.350587 — biochemistry — Posted on 2020-10-22
1307 PEPATAC: An optimized ATAC-seq pipeline with serial alignments
Smith, J. P.; Corces, M. R.; Xu, J.; Reuter, V. P.; Chang, H. Y.; Sheffield, N. C.
10.1101/2020.10.21.347054 — genomics — Posted on 2020-10-22
1313 Human bronchial epithelial cell-derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF-β-WNT crosstalk
Kadota, T.; Fujita, Y.; Araya, J.; Watanabe, N.; Fujimoto, S.; Kawamoto, H.; Minagawa, S.; Hara, H.; Takashi, O.; Yamamoto, Y.; Kuwano, K.; Ochiya, T.
10.1101/2020.10.22.349761 — molecular biology — Posted on 2020-10-22
1316 Broad transcriptional dysregulation of brain and choroid plexus cell types with COVID-19
Yang, A. C.; Kern, F.; Losada, P. M.; Maat, C. A.; Schmartz, G.; Fehlmann, T.; Schaum, N.; Lee, D. P.; Calcuttawala, K.; Vest, R. T.; Gate, D.; Berdnik, D.; McNerney, M. W.; Channappa, D.; Cobos, I.; Ludwig, N.; Schulz-Schaeffer, W. J.; Keller, A.; Wyss-Coray, T.
10.1101/2020.10.22.349415 — neuroscience — Posted on 2020-10-22
1317 Determinants of Real-Time fMRI Neurofeedback Performance and Improvement: a Machine Learning Mega-Analysis
Haugg, A.; Renz, F. M.; Nicholson, A. A.; Lor, C.; Goetzendorfer, S. J.; Sladky, R.; Skouras, S.; McDonald, A.; Craddock, C.; Hellrung, L.; Kirschner, M.; Herdener, M.; Koush, Y.; Papoutsi, M.; Keynan, J. N.; Hendler, T.; Cohen Kadosh, K.; Zich, C.; Kohl, S. H.; Hallschmid, M.; MacInnes, J.; Adcock, R. A.; Dickerson, K.; Chen, N.-K.; Young, K.; Bodurka, J.; Marxen, M.; Yao, S.; Becker, B.; Auer, T.; Schweizer, R.; Pamplona, G.; Lanius, R.; Emmert, K.; Haller, S.; Van De Ville, D.; Kim, D.-Y.; Lee, J.-H.; Marins, T.; Megumi, F.; Sorger, B.; Kamp, T.; Liew, S.-L.; Veit, R.; Spetter, M.; Weiskopf
10.1101/2020.10.21.349118 — neuroscience — Posted on 2020-10-22
1318 Low-frequency subthalamic neural oscillations are involved in explicit and implicit facial emotional processing - a local field potential study
Dondaine, T.; Duprez, J.; Houvenaghel, J.-F.; Modolo, J.; Haegelen, C.; Robert, G.; Millet, B.; Drapier, D.; Verin, M.; Sauleau, P.
10.1101/2020.10.21.348755 — neuroscience — Posted on 2020-10-22
1319 Single-cell Sequencing Reveals Brain/Spinal Cord Oligodendrocyte Precursor Heterogeneity and Requirement for mTOR in Cholesterol Biosynthesis and Myelin Maintenance
Khandker, L.; Jeffries, M. A.; Chang, Y.-J.; Mather, M. L.; Bourne, J. N.; Tafreshi, A. K.; Bozdagi-Gunal, O.; Macklin, W. B.; Wood, T. L.
10.1101/2020.10.22.349209 — neuroscience — Posted on 2020-10-22
1327 Theta-gamma coupling depends on breathing rate
Hammer, M.; Schwale, C.; Brankack, J.; Draguhn, A.; Tort, A. B.
10.1101/2020.10.22.349936 — neuroscience — Posted on 2020-10-22
1329 Through-scalp deep-brain stimulation in tether-free, naturally-behaving mice with widefield NIR-II illumination
Wu, X.; Jiang, Y.; Rommelfanger, N. J.; Yin, R.; Liu, J.; Cai, S.; Ren, W.; Shin, A.; Ong, K. S.; Pu, K.; Hong, G.
10.1101/2020.10.21.348037 — neuroscience — Posted on 2020-10-22
1332 Enhanced ultrasound neuromodulation in vitro using nanobubble actuators
Hou, X.; Qiu, Z.; Kala, S.; Guo, J.; Zhu, T.; Wong, K. F.; Zhu, J.; Xian, Q.; Yang, M.; Sun, L.
10.1101/2020.10.21.348870 — neuroscience — Posted on 2020-10-22
1336 TET2 drives 5hmc marking of GATA6 and epigenetically defines pancreatic ductal adenocarcinoma transcriptional subtypes
Eyres, M.; Lanfredini, S.; Burns, A.; Blake, A.; Willenbrock, F.; Goldin, R.; Hughes, D.; Hughes, S.; Thapa, A.; Valoulis, D.; Hubert, A.; D'Costa, Z.; Sabbagh, A.; Abraham, A. G.; Blancher, C.; Jones, S.; Verrill, C.; Silva, M.; Soonawalla, Z.; Maughan, T.; Schuh, A.; Mukherjee, S.; O'Neill, E.
10.1101/2020.10.22.342436 — cancer biology — Posted on 2020-10-22
1337 Two-photon microscopy at >500 volumes/second
Tsai, Y.-H.; Liu, C.-W.; Lin, W.-K.; Wang, C.-S.; Chiang, C.-H.; Singh, V. R.; So, P. T. C.; Chou, C.-F.; Chu, S.-W.
10.1101/2020.10.21.349712 — biophysics — Posted on 2020-10-22
1339 TruSight Oncology 500: Enabling Comprehensive Genomic Profiling and Biomarker Reporting with Targeted Sequencing
Zhao, C.; Jiang, T.; Ju, J. H.; Zhang, S.; Tao, J.; Fu, Y.; Lococo, J.; Dockter, J.; Powlowski, T.; Bilke, S.
10.1101/2020.10.21.349100 — bioinformatics — Posted on 2020-10-22
1340 SugarPy facilitates the universal, discovery-driven analysis of intact glycopeptides
Schulze, S.; Oltmanns, A.; Fufezan, C.; Kragenbring, J.; Mormann, M.; Pohlschroder, M.; Hippler, M.
10.1101/2020.10.21.349399 — bioinformatics — Posted on 2020-10-22
1346 Role of Udd protein and heterochromatin in transcriptional selection of individual rRNA genes in the Drosophila germline
Fefelova, E. A.; Pleshakova, I. M.; Pirogov, S. A.; Mikhaleva, E. A.; Poltorachenko, V. A.; Blokh, R. S.; Abramov, Y. A.; Romashin, D. D.; Gvozdev, V. A.; Klenov, M. S.
10.1101/2020.10.21.349613 — molecular biology — Posted on 2020-10-22
1348 Live poultry feeding and trading network and the transmission of avian influenza A(H5N6) virus in a large city in China, 2014-2015
Zhang, R.; Lei, Z.; Liu, C.; Zhu, Y.; Chen, J.; Yao, D.; Ou, X.; Ye, W.; Huang, Z.; Luo, L.; Sun, B.; Chen, T.
10.1101/2020.10.21.349787 — molecular biology — Posted on 2020-10-22
1350 Recurrent Switching Dynamical Systems Models for Multiple Interacting Neural Populations
Glaser, J. I.; Whiteway, M. R.; Cunningham, J. P.; Paninski, L.; Linderman, S. W.
10.1101/2020.10.21.349282 — neuroscience — Posted on 2020-10-22
1351 Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
Guo, Y.; Chomiak, A. A.; Hong, Y.; Lowe, C. C.; Chan, W.-C.; Andrade, J.; Pan, H.; Zhou, X.; Berezovski, E.; Monuki, E. S.; Feng, Y.
10.1101/2020.10.22.341784 — neuroscience — Posted on 2020-10-22
1355 Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction
Tribble, J. R.; Otmani, A.; Sun, S.; Ellis, S. A.; Cimaglia, G.; Vohra, R.; Joe, M.; Lardner, E.; Venkataraman, A. P.; Dominguez-Vicent, A.; Kokkali, E.; Rho, S.; Johannesson, G.; Burgess, R. W.; Fuerst, P. G.; Brautaset, R.; Kolko, M.; Morgan, J. E.; Crowston, J. G.; Votruba, M.; Williams, P. A.
10.1101/2020.10.21.348250 — neuroscience — Posted on 2020-10-22
1356 Age, wound size and position of injury - dependent vascular regeneration assay in growing leaves
Radhakrishnan, D.; Shanmukhan, A. P.; Kareem, A.; Mathew, M. M.; Varaparambathu, V.; Aiyaz, M.; Radha, R. K.; Mekala, K. R.; Shaji, A.; Prasad, K.
10.1101/2020.10.21.348680 — plant biology — Posted on 2020-10-22
1363 A Deep Learning Pipeline for Nucleus Segmentation
Zaki, G.; Gudla, P. R.; Lee, K.; Kim, J.; Ozbun, L.; Shachar, S.; Gadkari, M.; Jing, S.; Fraser, I. D.; Franco, L. M.; Misteli, T.; Pegoraro, G.
10.1101/2020.04.14.041020 — cell biology — Posted on 2020-10-22
1364 Distinct Phenotypes of SARS-CoV-2 Isolates Reveal Viral Traits Critical for Replication in Primary Human Respiratory Cells
Pohl, M. O.; Busnadiego, I.; Kufner, V.; Schmutz, S.; Zaheri, M.; Abela, I.; Trkola, A.; Huber, M.; Stertz, S.; Hale, B. G.
10.1101/2020.10.22.350207 — microbiology — Posted on 2020-10-22
1365 Immunogenicity of a new gorilla adenovirus vaccine candidate for COVID-19
Vitelli, A.; Capone, S.; Raggioli, A.; Gentile, M.; Battella, S.; Lahm, A.; Sommella, A.; Contino, A. M.; Urbanowicz, R. A.; Scala, R.; Barra, F.; Leuzzi, A.; Lilli, E.; Miselli, G.; Noto, A.; Ferraiuolo, M.; Talotta, F.; Tsoleridis, T.; Castilletti, C.; Matusali, G.; Colavita, F.; Lapa, D.; Meschi, S.; Capobianchi, M.; Soriani, M.; Folgori, A.; Ball, J. K.; Colloca, S.
10.1101/2020.10.22.349951 — immunology — Posted on 2020-10-22
1366 A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues
Nims, R.; Pferdehirt, L.; Ho, N.; Savadipour, A.; Lorentz, J.; Sohi, S.; Kassab, J.; Ross, A.; O'Conor, C.; Liedtke, W.; Zhang, B.; McNulty, A.; Guilak, F.
10.1101/2020.04.29.069294 — synthetic biology — Posted on 2020-10-22
1367 Analysis of SARS-CoV-2 ORF3a structure reveals chloride binding sites
Marquez-Miranda, V.; Rojas, M.; Duarte, Y.; Diaz-Franulic, I.; Holmgren, M.; Cachau, R.; Gonzalez-Nilo, F. D.
10.1101/2020.10.22.349522 — biophysics — Posted on 2020-10-22
1368 Databiology Lab CORONAHACK: Collection of Public COVID-19 Data
Caballero Perez, J.; de Blas Perez, C.; Leza Alvarez, F.; Caballero Contreras, J. M.
10.1101/2020.10.22.328864 — bioinformatics — Posted on 2020-10-22
1372 Plant Scaffolds Support Motor Recovery and Regeneration in Rat Spinal Cord Injury
Modulevsky, D. J.; Cuerrier, C. M.; Leblanc-Latour, M.; Hickey, R. J.; Obhi, R.-J. K.; Shore, I.; Galuta, A.; Walker, K. L. A.; Tsai, E. C.; Pelling, A. E.
10.1101/2020.10.21.347807 — bioengineering — Posted on 2020-10-22
1374 Mechanism of negative regulation of NF-κB by N4BP1
Shi, H.; Sun, L.; Wang, Y.; Liu, A.; Zhan, X.; Li, X.; Tang, M.; Anderton, P.; Hildebrand, S.; Quan, J.; Ludwig, S.; Moresco, E. M. Y.; Beutler, B.
10.1101/2020.10.21.349357 — immunology — Posted on 2020-10-22
1378 Yeast Ssd1 is a non-enzymatic member of the RNase II family with an alternative RNA recognition interface
Bayne, R. A.; Jayachandran, U.; Kasprowicz, A.; Bresson, S.; Tollervey, D.; Wallace, E. W. J.; Cook, A. G.
10.1101/2020.10.22.350314 — biochemistry — Posted on 2020-10-22
1379 Integrated Single Cell Atlas of Endothelial Cells of the Human Lung
Schupp, J. C.; Adams, T. S.; Cosme, C.; Brickman Raredon, M. S.; Omote, N.; Poli, S.; Rose, K.-A.; Manning, E.; Sauler, M.; DeIuliis, G.; Ahangari, F.; Neumark, N.; Yuan, Y.; Habermann, A. C.; Gutierrez, A. J.; Bui, L. T.; Meyer, K. B.; Nawijn, M. C.; Teichmann, S. A.; Banovich, N.; Kropski, J. A.; Niklason, L. E.; Pe'er, D.; Yan, X.; Homer, R.; Rosas, I. O.; Kaminski, N.
10.1101/2020.10.21.347914 — cell biology — Posted on 2020-10-22
1382 Essentiality of c-di-AMP in Bacillus subtilis: Bypassing mutations converge in potassium and glutamate homeostasis
Krüger, L.; Herzberg, C.; Rath, H.; Pedreira, T.; Poehlein, A.; Gundlach, J.; Daniel, R.; Völker, U.; Mäder, U.; Stülke, J.
10.1101/2020.09.03.280651 — microbiology — Posted on 2020-10-22
1385 Circadian- and sex-dependent increases in intravenous cocaine self-administration in Npas2 mutant mice
DePoy, L.; Becker-Krail, D.; Zong, W.; Petersen, K.; Shah, N.; Brandon, J. H.; Miguelino, A. M.; Tseng, G. C.; Logan, R.; McClung, C.
10.1101/788786 — neuroscience — Posted on 2020-10-22
1387 Engineered Reproductively Isolated Species Drive Reversible Population Replacement
Buchman, A.; Shriner, I.; Yang, T.; Liu, J.; Antoshechkin, I.; Marshall, J. M.; Perry, M. W.; Akbari, O. S.
10.1101/2020.08.09.242982 — bioengineering — Posted on 2020-10-22
1390 SALL4 controls cell fate in response to DNA base composition
Pantier, R.; Chhatbar, K.; Quante, T.; Skourti-Stathaki, K.; Cholewa-Waclaw, J.; Alston, G.; Alexander-Howden, B.; Lee, H. Y.; Cook, A. G.; Spruijt, C.; Vermeulen, M.; Selfridge, J.; Bird, A.
10.1101/2020.06.30.179481 — genomics — Posted on 2020-10-22
1391 Deeply sequenced infectious clones of key cassava begomovirus isolates from Cameroon
Hoyer, J. S.; Fondong, V. N.; Dallas, M. M.; Aimone, C. D.; Deppong, D. O.; Duffy, S.; Hanley-Bowdoin, L.
10.1101/2020.08.10.244335 — microbiology — Posted on 2020-10-22
1392 A Rat Model of a Focal Mosaic Expression of PCDH19 Replicates Human Brain Developmental Abnormalities and Behaviors
Cwetsch, A. W.; Narducci, R.; Bolla, M.; Pinto, B.; Perlini, L.; Bassani, S.; Passafaro, M.; Cancedda, L.
10.1101/2020.06.12.145508 — neuroscience — Posted on 2020-10-22
1395 x Pseudorhiza nieschalkii (Senghas) P.F.Hunt nothosubsp. siculorumH.Kertesz & N.Anghelescu, 2020AN INTERGENERIC ORCHID HYBRID NEW TO SCIENCE FOUND IN TERRA SICULORUM, ROMANIA
Anghelescu (aka Nora De Angelli), N. E.; KERTESZ, H.; CONSTANTIN, N.; SIMON GRUITA, A.; DUTA CORNESCU, G.; POJOGA, M. D.; GEORGESCU, M. I.; PETRA, S. A.; TOMA, F.
10.1101/2020.10.21.345462 — plant biology — Posted on 2020-10-22
1397 TRAPID 2.0: a web application for taxonomic and functional analysis of de novo transcriptomes
Bucchini, F.; Del Cortona, A.; Kreft, Łukasz; Botzki, A.; Van Bel, M.; Vandepoele, K.
10.1101/2020.10.19.345835 — bioinformatics — Posted on 2020-10-22
1402 Executive modulation of brain reward systems endows goals with value
McDougle, S. D.; Ballard, I. C.; Baribault, B.; Bishop, S. J.; Collins, A. G. E.
10.1101/2020.10.21.348938 — neuroscience — Posted on 2020-10-22
1403 Genetic influences on cell type specific gene expression and splicing during neurogenesis elucidate regulatory mechanisms of brain traits
Aygün, N.; Elwell, A. L.; Liang, D.; Lafferty, M. J.; Cheek, K. E.; Courtney, K. P.; Mory, J.; Hadden-Ford, E.; Krupa, O.; de la Torre-Ubieta, L.; Geschwind, D. H.; Love, M. I.; Stein, J. L.
10.1101/2020.10.21.349019 — genetics — Posted on 2020-10-22
1405 The polymicrogyria-associated GPR56 promoter preferentially drives gene expression in developing GABAergic neurons in common marmosets
Murayama, A. Y.; Kuwako, K.-i.; Okahara, J.; Bae, B.-I.; Okuno, M.; Mashiko, H.; Shimogori, T.; Walsh, C. A.; Sasaki, E.; Okano, H.
10.1101/2020.10.21.348821 — neuroscience — Posted on 2020-10-22
1406 HPF1-dependent PARP activation promotes LIG3-XRCC1-mediated backup pathway of Okazaki fragment ligation
Kumamoto, S.; Nishiyama, A.; Chiba, Y.; Miyashita, R.; Konishi, C.; Azuma, Y.; Nakanishi, M.
10.1101/2020.10.21.348292 — molecular biology — Posted on 2020-10-21
1407 GWAS analysis combined with QTL mapping identify CPT3 and ABH as genes underlying dolichol accumulation in Arabidopsis
Gawarecka, K.; Siwinska, J.; Poznanski, J.; Onysk, A.; Surowiecki, P.; Surmacz, L.; Ahn, J. H.; Korte, A.; Swiezewska, E.; Ihnatowicz, A.
10.1101/2020.10.21.348912 — genomics — Posted on 2020-10-21
1410 A deep learning algorithm for 3D cell detection in whole mouse brain image datasets
Tyson, A. L.; Rousseau, C. V.; Niedworok, C. J.; Keshavarzi, S.; Tsitoura, C.; Margrie, T. W.
10.1101/2020.10.21.348771 — neuroscience — Posted on 2020-10-21
1412 Nanoscopic Structural Fluctuations of Disassembling Microtubules Revealed by Label-Free Super-Resolution Microscopy
Vala, M.; Bujak, L.; Marin, A. G.; Holanova, K.; Henrichs, V.; Braun, M.; Lansky, Z.; Piliarik, M.
10.1101/2020.10.21.348904 — biophysics — Posted on 2020-10-21
1413 Microengineered three-dimensional collagen landscapes with independently tunable fiber anisotropy and directionality
Ahmed, A.; Joshi, I. M.; Mansouri, M.; Larson, S.; Gholizadeh, S.; Allahyari, Z.; Forouzandeh, F.; Borkholder, D. A.; Gaborski, T. R.; Abhyankar, V. V.
10.1101/2020.06.12.148346 — bioengineering — Posted on 2020-10-21
1414 EVQuant; high-throughput quantification and characterization of extracellular vesicle (sub)populations
Hartjes, T. A.; Slotman, J. A.; Vredenbregt-van den Berg, M. S.; Dits, N.; Van der Meel, R.; Duijvesz, D.; Kulkarni, J. A.; French, P. J.; van Cappellen, W. A.; Schiffelers, R. M.; Houtsmuller, A. B.; Jenster, G.; van Royen, M. E.
10.1101/2020.10.21.348375 — bioengineering — Posted on 2020-10-21
1415 Aversive responses to L-arabinose in caterpillars of Helicoverpa armigera (Hübner)
Sun, L.; Hong, Z.-Z.; Ma, Y.; Hou, W.; Liu, L.; Zhao, X.; Yan, F.; Yin, X.; Wang, C.-Z.; Tang, Q.
10.1101/2020.07.20.213033 — animal behavior and cognition — Posted on 2020-10-21
1416 Haplotype-phased common marmoset embryonic stem cells for genome editing using CRISPR/Cas9
Zhou, B.; Ho, S. S.; Leung, L. C.; Ward, T. R.; Ho, M.; Plastini, M. J.; Vermilyea, S. C.; Emborg, M. E.; Golos, T. G.; Albertelli, M. A.; Mourrain, P.; Perrin, D.; Parker, K. J.; Urban, A. E.
10.1101/373886 — genetics — Posted on 2020-10-21
1419 Prediction and in vitro silencing of two lipid biosynthetic genes viz. SCD and SREBP1 in chicken using RNA interference
Bhattacharya, T.; Govardhana Sagar, N.; Rajendra Prasad, A.; Chatterjee, R. N.; Kumar, P.; Bhushan, B.; Guru Vishnu, P.
10.1101/2020.10.21.348482 — molecular biology — Posted on 2020-10-21
1421 Assessment of two DNA extraction kits for profiling poultry respiratory microbiota from multiple sample types
Abundo, M. E. C.; Ngunjiri, J.; Taylor, K. J. M.; Ji, H.; Ghorbani, A.; KC, M.; Weber, B. P.; Johnson, T. J.; Chang-Won, L.
10.1101/2020.10.21.348508 — microbiology — Posted on 2020-10-21
1423 Title: Reliability, sensitivity and predictive value of fMRI during multiple object tracking as a marker of cognitive training gain in combination with tDCS in stroke survivors
Kolskaar, K. K.; Richard, G.; Alnaes, D.; Dorum, E. S.; Sanders, A.-M.; Ulrichsen, K. M.; Monereo Sanchez, J.; Ihle-Hansen, H.; Nordvik, J. E.; Westlye, L. T.
10.1101/603985 — neuroscience — Posted on 2020-10-21
1424 PharmaNet: Pharmaceutical discovery with deep recurrent neural networks.
Ruiz Puentes, P.; Valderrama, N.; Gonzalez, C.; Daza, L.; Munoz-Camargo, C.; Cruz, J. C.; Arbelaez, P.
10.1101/2020.10.21.348441 — bioinformatics — Posted on 2020-10-21
1427 Structure of the light harvesting 2 complex reveals two carotenoid energy transfer pathways in a photosynthetic bacterium
Gardiner, A. T.; Naydenova, K.; Hartmann, P. C.; Nguyen-Phan, T. C.; Russo, C. J.; Sader, K.; Hunter, C. N.; Cogdell, R. J.; Qian, P.
10.1101/2020.10.21.349431 — biochemistry — Posted on 2020-10-21
1430 Mutating PINK1 gene by paired truncated sgRNA/Cas9-D10A in Cynomolgus Monkey
Chen, Z.; Wang, J.; Kang, Y.; Yang, Q.; Gu, X.; Zhi, D.; Yan, L.; Shen, B.; Niu, Y.
10.1101/2020.10.21.348862 — genetics — Posted on 2020-10-21
1433 Nuclear deformation causes DNA damage by increasing replication stress
Shah, P.; Hobson, C. M.; Cheng, S.; Colville, M. J.; Paszek, M.; Superfine, R.; Lammerding, J.
10.1101/2020.06.12.148890 — cell biology — Posted on 2020-10-21
1434 A burst in T cell receptor translation mediated by eIF3 interactions with T cell receptor mRNAs
De Silva, D.; Ferguson, L.; Smith, B. E.; Chin, G. H.; Apathy, R. A.; Roth, T. L.; Kudla, M.; Marson, A.; Ingolia, N. T.; Cate, J. H. D.
10.1101/2019.12.20.885558 — molecular biology — Posted on 2020-10-21
1435 The molecular basis of Acinetobacter baumannii cadmium toxicity and resistance
Alquethamy, S. F.; Adams, F. G.; Maharjan, R.; Delgado, N. N.; Zang, M.; Paton, J. C.; Hassan, K. A.; Paulsen, I. T.; McDevitt, C. A.; Cain, A. K.; Eijkelkamp, B. A.
10.1101/2020.10.20.348086 — microbiology — Posted on 2020-10-21
1437 Multi-omic Single-cell Atlas Reveals Broad Ex Vivo Effects on Human Immunobiology
Savage, A. K.; Gutschow, M. V.; Chiang, T.; Henderson, K.; Green, R.; Chaudhari, M.; Swanson, E.; Heubeck, A. T.; Kondza, N.; Burley, K. C.; Genge, P. C.; Lord, C.; Smith, T.; Beaubien, A.; Goldy, J.; Bolouri, H.; Buckner, J. H.; Meijer, P.; Coffey, E. M.; Li, X.-j.; Skene, P. J.; Torgerson, T. R.; Bumol, T. F.
10.1101/2020.10.18.344663 — immunology — Posted on 2020-10-21
1438 Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition
Stoklund Dittlau, K.; Krasnow, E. N.; Fumagalli, L.; Vandoorne, T.; Baatsen, P.; Kerstens, A.; Giacomazzi, G.; Pavie, B.; Sampaolesi, M.; Van Damme, P.; Van Den Bosch, L.
10.1101/2020.10.21.346874 — neuroscience — Posted on 2020-10-21
1440 Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors
Molina, L. M.; Zhu, J.; Li, Q.; Pradhan-Sundd, T.; Sayed, K.; Jenkins, N.; Vats, R.; Ko, S.; Hu, S.; Poddar, M.; Singh, S.; Tao, J.; Sundd, P.; Singhi, A.; Watkins, S. C.; Ma, X.; Benos, P. V.; Feranchak, A.; Nejak-Bowen, K.; Watson, A.; Bell, A.; Monga, S. P.
10.1101/2020.10.21.349159 — pathology — Posted on 2020-10-21
1441 Combination of arsenic trioxide epigallocatechin-3-gallate and Resveratrol synergistically suppresses the growth and invasion in Brain tumor cell lines
Sajjadi, R. S.; Ahmadi, S.; Mantashloo, M.; Mehrpour Layeghi, S.; Asgari, Y.; Ghorbani, M.; Mohammadi, S. D.; Saffari, M.
10.1101/2020.10.21.348219 — cancer biology — Posted on 2020-10-21
1442 HPM Live μ for full CLEM workflow
Heiligenstein, X.; de Beer, M.; Heiligenstein, J.; Eyraud, F.; Manet, L.; Schmitt, F.; Lamers, E.; Lindenau, J.; Kea-te Lindert, M.; Salamero, J.; Raposo, G.; sommerdijk, N.; Belle, M.; Akiva, A.
10.1101/2020.09.03.281956 — biophysics — Posted on 2020-10-21
1444 Molecular determinants for α-tubulin methylation by SETD2
Kearns, S.; Mason, F. M.; Rathmell, W. K.; Park, I. Y.; Walker, C.; Verhey, K. A.; Cianfrocco, M. A.
10.1101/2020.10.21.349365 — biochemistry — Posted on 2020-10-21
1445 The molecular coupling between substrate recognition and ATP turnover in a AAA+ hexameric helicase loader
Puri, N.; Fernandez, A. J.; O'Shea Murray, V. L.; McMillan, S.; Keck, J. L.; Berger, J. M.
10.1101/2020.10.21.345918 — biochemistry — Posted on 2020-10-21
1446 High-throughput transcriptomics and benchmark concentration modeling for potency ranking of per- and polyfluoroalkyl substances (PFAS) in exposed human liver cell spheroids
Reardon, A. J. F.; Rowan-Carroll, A.; Ferguson, S. S.; Leingartner, K.; Gagne, R.; Kuo, B.; Williams, A.; Lorusso, L.; Bourdon-Lacombe, J.; Carrier, R.; Moffat, I.; Yauk, C. L.; Atlas, E.
10.1101/2020.10.20.347328 — genomics — Posted on 2020-10-21
1447 Intraflagellar transport-A deficiency ameliorates ADPKD in a renal tubular- and maturation-dependent manner
Wang, W.; Silva, L.; Wang, H.; Kavanaugh, M. A.; Pottorf, T.; Allard, B.; Jacobs, D.; Dong, R.; Cornelius, J.; Chaturvedi, A.; Pritchard, M.; Sharma, M.; Slawson, C.; Wallace, D.; Calvet, J.; Tran, P.
10.1101/2020.04.26.061796 — genetics — Posted on 2020-10-21
1449 Undaria pinnatifida exudates trigger shifts in seawater chemistry and microbial communities from Atlantic Patagonian coasts
Lozada, M.; Dieguez, M. C.; Garcia, P. E.; Bigatti, G.; Livore, J. P.; Giarratano, E.; Gil, M. N.; Dionisi, H. M.
10.1101/2020.10.21.349233 — microbiology — Posted on 2020-10-21
1451 Clustering and erratic movement patterns of syringe-injected versus mosquito-inoculated malaria sporozoites underlie decreased infectivity
de Korne, C. M.; Winkel, B. M.; van Oosterom, M. N.; Chevalley-Maurel, S.; Houwing, K.; Sijtsma, J. C.; Baalbergen, E.; Franke-Fayard, B. M.; van Leeuwen, F. W.; Roestenberg, M.
10.1101/2020.10.21.348573 — microbiology — Posted on 2020-10-21
1453 Limb-clasping, cognitive deficit and increased vulnerability to kainic acid -induced seizures in neuronal GPI anchor deficiency mouse models
Kandasamy, L. C.; Tsukamoto, M.; Banov, V.; Tsetsegee, S.; Nagasawa, Y.; Kato, M.; Matsumoto, N.; Takeda, J.; Itohara, S.; Ogawa, S.; Young, L. J.; Zhang, Q.
10.1101/2020.10.21.348334 — neuroscience — Posted on 2020-10-21
1455 Inhibitory interneurons show early dysfunction in a SOD1 mouse model of ALS
Cavarsan, C. F.; Steele, P. R.; McCane, L. M.; LaPre, K. J.; Puritz, A. C.; Katenka, N.; Quinlan, K. A.
10.1101/2020.10.21.348359 — neuroscience — Posted on 2020-10-21
1457 Unicellular associative conditioning: an interspecies analysis
Pujante, J. C.; Roldan, C. B.; Celada, I. M.; Fedetz, M.; Fernandez, L. M.; Perez-Irezabal, G. P.-Y.; Lopez, M. D. B.; Berdieva, M.; Goodkov, A.; Fernandez de Villaverde, J. I. L.; Knafo, S.; De la Fuente, I. M.
10.1101/2020.10.19.346007 — systems biology — Posted on 2020-10-21
1462 Swi6/HP1 binding to RNA-DNA hybrids initiates heterochromatin assembly at the centromeric dg-dh repeats in Fission Yeast
Singh, J.; Kumar, J.; Haldar, S.; Gupta, N.; Kumar, V.; Thakur, M.; Chandradoss, K. R.; Ghose, D.; Dutta, D.; Sandhu, K. S.
10.1101/2020.10.21.349050 — genetics — Posted on 2020-10-21
1464 Genomic properties of variably methylated retrotransposons in mouse
Elmer, J. L.; Hay, A. D.; Kessler, N. J.; Bertozzi, T. M.; Ainscough, E.; Ferguson-Smith, A. C.
10.1101/2020.10.21.349217 — genetics — Posted on 2020-10-21
1466 Characterization of Constitutive macro-ER-phagy
Lipatova, Z.; Gyurkovska, V.; Zhang, S. F.; Segev, N.
10.1101/2020.10.21.349167 — cell biology — Posted on 2020-10-21
1469 High-resolution mapping of the neutralizing and binding specificities of polyclonal rabbit serum elicited by HIV Env trimer immunization
Dingens, A. S.; Pratap, P.; Malone, K.; Hilton, S. K.; Ketas, T.; Cottrell, C. A.; Overbaugh, J.; Moore, J. P.; Klasse, P. J.; Ward, A. B.; Bloom, J. D.
10.1101/2020.10.21.348623 — microbiology — Posted on 2020-10-21
1470 Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype
Guha, R.; Mathioudaki, A.; Doumbo, S.; Doumtabe, D.; Skinner, J.; Arora, G.; Siddiqui, S.; Li, S.; Kayentao, K.; Ongoiba, A.; Zaugg, J. B.; Traore, B.; Crompton, P. D.
10.1101/2020.10.21.346197 — immunology — Posted on 2020-10-21
1474 x Pseudorhiza nieschalkii (Senghas) P.F.Hunt nothosubsp. siculorumH.Kertesz & N.Anghelescu, 2020AN INTERGENERIC ORCHID HYBRID NEW TO SCIENCE FOUND IN TERRA SICULORUM, ROMANIA
Anghelescu (aka Nora De Angelli), N. E.; KERTESZ, H.; CONSTANTIN, N.; SIMON GRUITA, A.; DUTA CORNESCU, G.; POJOGA, M. D.; GEORGESCU, M. I.; PETRA, S. A.; TOMA, F.
10.1101/2020.10.21.345462 — plant biology — Posted on 2020-10-21
1475 Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion
Jackson, P. K.; Kim, S. K.; Wu, C.-T.; Hilgendorf, K.; Bevacqua, R.; Hang, Y.; Demeter, J.
10.1101/2020.10.21.349423 — physiology — Posted on 2020-10-21
1481 Epistatic interactions shape the interplay between beneficial alleles and gain or loss of pathways in the evolution of novel metabolism
Bruger, E. L.; Chubiz, L. M.; Rojas Echenique, J. I.; Renshaw, C. J.; Espericueta, N. V.; Draghi, J. A.; Marx, C. J.
10.1101/2020.10.20.347948 — evolutionary biology — Posted on 2020-10-21
1483 Higher Variability in Fungi Compared to Bacteria in the Foraging Honey Bee
Decker, L.; San Juan, P. A.; Warren, M. L.; Duckworth, C. E.; Gao, C.; Fukami, T.
10.1101/2020.10.20.348128 — ecology — Posted on 2020-10-21
1485 Direct visualization of epithelial microvilli biogenesis
Gaeta, I. M.; Meenderink, L. M.; Postema, M. M.; Cencer, C. S.; Tyska, M. J.
10.1101/2020.10.21.341248 — cell biology — Posted on 2020-10-21
1486 Structural and biochemical characterization of bifunctional XynA
Xie, W.; Yu, Q.; Liu, Y.; Cao, R.; Zhang, R.; Wang, S.; Zhan, R.; Liu, Z.; Wang, K.; Wang, C.
10.1101/2020.10.20.348094 — molecular biology — Posted on 2020-10-21
1487 The molecular basis of Acinetobacter baumannii cadmium toxicity and resistance
Alquethamy, S. F.; Adams, F. G.; Maharjan, R.; Delgado, N. N.; Zang, M.; Paton, J. C.; Hassan, K. A.; Paulsen, I. T.; McDevitt, C. A.; Cain, A. K.; Eijkelkamp, B. A.
10.1101/2020.10.20.348086 — microbiology — Posted on 2020-10-21
1489 Molecular forms of Anopheles subpictus s.l. and Anopheles sundaicus s.l. in the Indian subcontinent
Sindhania, A.; Das, M. K.; Sharma, G.; Surendran, S. N.; Kaushal, B. R.; Lohani, H. P.; Singh, O. P.
10.1101/2020.10.20.345272 — zoology — Posted on 2020-10-21
1490 HIGH FAT DIET STIMULATES BETA-OXIDATION, ALTERS ELECTRICAL PROPERTIES AND INDUCES ADIPOGENICITY OF ATRIA IN OBESE MICE
Suffee, N.; Baptista, E.; Piquereau, J.; Ponnaiah, M.; Doisne, N.; Ichou, F.; Lhomme, M.; Pichard, C.; Galand, V.; Mougenot, N.; Dilanian, G.; Lucats, L.; Balse, E.; Mericskay, M.; Le Goff, W.; Hatem, S. N.
10.1101/2020.10.20.347161 — physiology — Posted on 2020-10-21
1496 TRAPID 2.0: a web application for taxonomic and functional analysis of de novo transcriptomes
Bucchini, F.; Del Cortona, A.; Kreft, Łukasz; Botzki, A.; Van Bel, M.; Vandepoele, K.
10.1101/2020.10.19.345835 — bioinformatics — Posted on 2020-10-21
1499 Signature of selection in composite Vrindavani cattle of India
Singh, A.; Mehrotra, A.; Gondro, C.; Romero, A. R.; Pandey, A. K.; A, K.; Bashir, A.; Mishra, B. P.; Dutt, T.; KUMAR, A.
10.1101/2020.10.19.344747 — genetics — Posted on 2020-10-21
1500 A phylodynamic workflow to rapidly gain insights into the dispersal history and dynamics of SARS-CoV-2 lineages
Dellicour, S.; Durkin, K.; Hong, S. L.; Vanmechelen, B.; Marti-Carreras, J.; Gill, M. S.; Meex, C.; Bontems, S.; Andre, E.; Gilbert, M.; Walker, C.; De Maio, N.; Faria, N. R.; Hadfield, J.; Hayette, M.-P.; Bours, V.; Wawina-Bokalanga, T.; Artesi, M.; Baele, G.; Maes, P.
10.1101/2020.05.05.078758 — evolutionary biology — Posted on 2020-10-21
1501 Alpha globin variation in the long-tailed macaque suggests malaria selection
Faust, C. L.; Rangkuti, F.; Preston, S. G.; Boyd, A.; Flammer, P.; Bia, B.; Rose, N. J.; Piel, F. N.; Smith, A. L.; Dobson, A. P.; Gupta, S.; Penman, B. S.
10.1101/2020.10.21.344853 — evolutionary biology — Posted on 2020-10-21
1506 The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity
Stormo, A. E. D.; FitzGibbon, M.; Shavarebi, F.; Earley, E. M.; Lum, L. S.; Verschueren, E.; Swaney, D. L.; Skibinski, G.; Ravisankar, A.; van Haren, J.; Davis, E. J.; Johnson, J. R.; Von Dollen, J.; Mirescu, C.; Iaccarino, C.; Dauer, W. T.; Nichols, R. J.; Wittmann, T.; Cox, T. C.; Finkbeiner, S.; Krogan, N. J.; Oakes, S. A.; Hiniker, A.
10.1101/2020.10.21.336578 — molecular biology — Posted on 2020-10-21
1508 Contribution of noncanonical antigens to virulence and adaptive immunity in human infection with enterotoxigenic E. coli
Kuhlmann, F. M.; Laine, R. O.; Afrin, S.; Nakajima, R.; Akhtar, M.; Vickers, T. J.; Parker, K.; Nizam, N.; Grigura, V.; Goss, C. W.; Felgner, P. L.; Rasko, D.; Qadri, F.; Fleckenstein, J. M.
10.1101/2020.10.20.348110 — microbiology — Posted on 2020-10-21
1509 Mitohormesis reprograms macrophage metabolism to enforce tolerance
Timblin, G. A.; Tharp, K. M.; Ford, B.; Winchester, J. M.; Wang, J.; Zhu, S.; Khan, R. I.; Louie, S. K.; Iavarone, A. T.; ten Hoeve, J.; Nomura, D. K.; Stahl, A.; Saijo, K.
10.1101/2020.10.20.347443 — immunology — Posted on 2020-10-21
1510 Behavioral and brain signatures of substance use vulnerability in childhood
Rapuano, K. M.; Rosenberg, M. D.; Maza, M. T.; Dennis, N.; Dorji, M.; Greene, A. S.; Horien, C.; Scheinost, D.; Constable, R. T.; Casey, B.
10.1101/2020.10.19.346403 — neuroscience — Posted on 2020-10-21
1513 Deep learning model fitting for diffusion-relaxometry: a comparative study
Grussu, F.; Battiston, M.; Palombo, M.; Schneider, T.; Gandini Wheeler-Kingshott, C. A. M.; Alexander, D. C.
10.1101/2020.10.20.347625 — neuroscience — Posted on 2020-10-21
1514 Mice alternate between discrete strategies during perceptual decision-making
Ashwood, Z. C.; Roy, N. A.; Stone, I. R.; International Brain Laboratory, T.; Churchland, A. K.; Pouget, A.; Pillow, J. W.
10.1101/2020.10.19.346353 — neuroscience — Posted on 2020-10-21
1515 Auditory Decisions in the Supplementary Motor Area
Moran, I.; Perez-Oribe, J.; Melchor, J.; Figueroa, T.; Lemus, L.
10.1101/2020.10.20.347864 — neuroscience — Posted on 2020-10-21
1518 Higher-order hub cells involved in feedforward motifs as critical factors in epileptic network instability
Hadjiabadi, D. H.; Lovett-Barron, M.; Raikov, I.; Sparks, F.; Liao, Z.; Baraban, S. C.; Leskovec, J.; Losonczy, A.; Deisseroth, K.; Soltesz, I.
10.1101/2020.10.20.340364 — neuroscience — Posted on 2020-10-21
1519 The cowboy effect: robot gaze influences human decisions
Belkaid, M.; Kompatsiari, K.; de Tommaso, D.; Zablith, I.; Wykowska, A.
10.1101/2020.10.21.345876 — neuroscience — Posted on 2020-10-21
1520 SpecSeg: cross spectral power-based segmentation of neurons and neurites in chronic calcium imaging datasets
de Kraker, L.; Seignette, K.; Thamizharasu, P.; Ferreira Pica, I.; Levelt, C. N.; van der Togt, C.
10.1101/2020.10.20.345371 — neuroscience — Posted on 2020-10-21
1523 A G protein-coupled receptor-like module regulates Cellulose Synthase secretion from the endomembrane system in Arabidopsis
McFarlane, H. E.; Mutwil-Anderwald, D.; Verbancic, J.; Picard, K. L.; Gookin, T. E.; Froehlich, A.; Trindade, L. M.; Alonso, J. M.; Assmann, S. M.; Persson, S.
10.1101/2020.10.20.345868 — plant biology — Posted on 2020-10-21
1525 Partial epithelial-to-mesenchymal transition is prognostic and associates with Slug in head and neck cancer
Schinke, H.; Pan, M.; Akyol, M.; Kranz, G.; Libl, D.; Simon, F.; Canis, M.; Baumeister, P.; Gires, O.
10.1101/2020.10.20.346692 — cancer biology — Posted on 2020-10-21
1529 Inferring spatially transient gene expression pattern from spatial transcriptomic studies
Kueckelhaus, J.; Ehr, J. v.; Ravi, V. M.; Will, P.; Joseph, K. M.; Beck, J.; Hofmann, U. G.; Delev, D.; Schnell, O.; Heiland, H. D.
10.1101/2020.10.20.346544 — bioinformatics — Posted on 2020-10-21
1530 Dual-view light-sheet imaging through tilted glass interface using a deformable mirror
Vladimirov, N.; Preusser, F.; Wisniewski, J.; Yaniv, Z.; Desai, R. A.; Woehler, A.; Preibisch, S.
10.1101/2020.10.20.345306 — bioengineering — Posted on 2020-10-21
1531 HAP-multitag, a PET and positive MRI contrast nanotracer for the longitudinal characterization of vascular calcifications in atherosclerosis
Pellico, J.; Fernandez-Barahona, I.; Ruiz-Cabello, J.; Gutierrez, L.; Sanchez-Guisado, M. J.; Aiestaran-Zelaia, I.; Martinez-Parra, L.; Rodriguez, I.; Bentzon, J.; Herranz, F.
10.1101/2020.10.20.345843 — bioengineering — Posted on 2020-10-21
1532 Neighborhood environment, social cohesion, and epigenetic aging
Martin, C. L.; Ward-Caviness, C.; Dhingra, R.; Zikry, T. M.; Galea, S.; Wildman, D. E.; Koenen, K. C.; Uddin, M.; Aiello, A. E.
10.1101/2020.10.19.345777 — genomics — Posted on 2020-10-21
1533 Leveraging supervised learning for functionally-informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs
Wang, Q. S.; Kelley, D. R.; Ulirsch, J.; Kanai, M.; Sadhuka, S.; Cui, R.; Albors, C.; Cheng, N.; Okada, Y.; The Biobank Japan Project, ; Aguet, F.; Ardlie, K. G.; MacArthur, D. G.; Finucane, H. K.
10.1101/2020.10.20.347294 — genomics — Posted on 2020-10-21
1535 Novel Asgard archaea phylum Hermodarchaeota degrade alkanes and aromatics via alkyl/benzyl-succinate synthase and benzoyl-CoA pathway
Zhang, J.-W.; Dong, H.; Hou, L.-J.; Liu, Y.; Ou, Y.-F.; Zheng, Y.-L.; Han, P.; Liang, X.; Yin, G.-Y.; Wu, D.-M.; Liu, M.; Li, M.
10.1101/2020.10.19.346239 — genomics — Posted on 2020-10-21
1537 Diet unmasks genetic variants that regulate lifespan in outbred Drosophila
Pallares, L. F.; Lea, A. J.; Han, C.; Filippova, E. V.; Andolfatto, P.; Ayroles, J. F.
10.1101/2020.10.19.346312 — evolutionary biology — Posted on 2020-10-21
1539 Restructuring of genomic provinces of surface ocean plankton under climate change
Fremont, P.; Gehlen, M.; Vrac, M.; Leconte, J.; Wincker, P.; Iudicone, D.; Jaillon, O.
10.1101/2020.10.20.347237 — ecology — Posted on 2020-10-21
1544 Experience replay supports non-local learning
Liu, Y.; Mattar, M.; Behrens, T.; Daw, N.; Dolan, R. J.
10.1101/2020.10.20.343061 — neuroscience — Posted on 2020-10-21
1545 A multimodal cell census and atlas of the mammalian primary motor cortex
BRAIN Initiative Cell Census Network (BICCN), ; Adkins, R. S.; Aldridge, A. I.; Allen, S.; Ament, S. A.; An, X.; Armand, E.; Ascoli, G. A.; Bakken, T. E.; Bandrowski, A.; Banerjee, S.; Barkas, N.; Bartlett, A.; Bateup, H. S.; Behrens, M. M.; Berens, P.; Berg, J.; Bernabucci, M.; Bernaerts, Y.; Bertagnolli, D.; Biancalani, T.; Boggeman, L.; Booeshaghi, A. S.; Bowman, I.; Bravo, H. C.; Cadwell, C. R.; Callaway, E. M.; Carlin, B.; O'Connor, C.; Carter, R.; Casper, T.; Castanon, R. G.; Castro, J. R.; Chance, R. K.; Chatterjee, A.; Chen, H.; Chun, J.; Colantuoni, C.; Crabtree, J.; Creasy, H.; Cric
10.1101/2020.10.19.343129 — neuroscience — Posted on 2020-10-21
1547 HIV-1 gp120 impairs spatial memory through CREB
Shrestha, J.; Santerre, M.; Allen, C. N.; Arjona, S. P.; Mukerjee, R.; Park, J.; Bagashev, A.; Wang, Y.; Kaul, M.; Chin, J.; Sawaya, B. E.
10.1101/2020.10.20.347146 — neuroscience — Posted on 2020-10-21
1552 Hippocampal replay of experience at real-world speeds
Denovellis, E. L.; Gillespie, A. K.; Coulter, M. E.; Kay, K.; Sosa, M.; Chung, J. E.; Eden, U. T.; Frank, L. M.
10.1101/2020.10.20.347708 — neuroscience — Posted on 2020-10-21
1554 A meta-analysis of mesophyll conductance to CO2 in relation to major abiotic stresses in poplar species
Elferjani, R.; Benomar, L.; Momayyezi, M.; Tognetti, R.; Niinemets, U.; Soolanayakanahally, R.; Theroux-Rancourt, G.; Tosens, T.; Lamara, M.; Ripullone, F.; Bilodeau-Gauthier, S.; Lamhamedi, M.; Calfapietra, C.
10.1101/2020.10.19.346270 — plant biology — Posted on 2020-10-21
1555 Circadian benefits of exercise training reflect metabolic and structural flexibility
Duglan, D.; Casanova Vallve, N.; Vaughan, M. E.; Handzlik, M. K.; Fan, W.; Yu, R.; Liddle, C.; Downes, M.; Chan, A. B.; Pariollaud, M.; Afetian, M. E.; Metallo, C.; Evans, R.; Lamia, K. A.
10.1101/2020.10.19.346015 — physiology — Posted on 2020-10-21
1556 A cross-species drug discovery pipeline to identify and validate new treatments for osteosarcoma
Somarelli, J.; Rupprecht, G.; Altunel, E.; Flamant, E.; Rao, S. R.; Sivaraj, D.; Lazarides, A.; Hoskinson, S.; Sheth, M.; Cheng, S.; Kim, S. Y.; Ware, K.; Agarwal, A.; Cullen, M.; Selmic, L.; Eward, C.; Everitt, J. I.; McCall, S.; Eward, W.; Hsu, D.
10.1101/2020.10.19.346387 — cancer biology — Posted on 2020-10-21
1557 Tracking changes in behavioural dynamics using prediction error
Lorimer, T.; Goodridge, R.; Bock, A. K.; Agarwal, V.; Saberski, E.; Sugihara, G.; Rifkin, S. A.
10.1101/2020.10.19.346080 — bioinformatics — Posted on 2020-10-21
1562 Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions
Krainer, G.; Welsh, T. J.; Joseph, J. A.; Espinosa, J. R.; Wittmann, S.; de Csillery, E.; Sridhar, A.; Toprakcioglu, Z.; Gudiskyte, G.; Czekalska, M. A.; Arter, W. E.; St George-Hyslop, P.; Hyman, A. A.; Collepardo-Guevara, R.; Alberti, S.; Knowles, T. P.
10.1101/2020.05.04.076299 — biophysics — Posted on 2020-10-21
1564 Knockout of zebrafish desmin genes does not cause skeletal muscle degeneration but alters calcium flux
Kayman Kurekci, G.; Kural Mangit, E.; Koyunlar, C.; Unsal, S.; Saglam, B.; Ergin, B.; Uyanik, I.; Boustanabadimaralan Duz, N.; Talim, B.; Purali, N.; Hughes, S. M.; Dincer, P. R.
10.1101/2020.10.16.342485 — developmental biology — Posted on 2020-10-21
1566 Structural basis for the inhibition of the SARS-CoV-2 RNA-dependent RNA polymerase by favipiravir-RTP
Naydenova, K.; Muir, K. W.; Wu, L.-F.; Zhang, Z.; Coscia, F.; Peet, M. J.; Castro-Hartmann, P.; Qian, P.; Sader, K.; Dent, K.; Kimanius, D.; Sutherland, J. D.; Lowe, J.; Barford, D.; Russo, C. J.
10.1101/2020.10.21.347690 — molecular biology — Posted on 2020-10-21
1567 Preclinical study of DNA vaccines targeting SARS-CoV-2
Hayashi, H.; Sun, J.; Yanagida, Y.; Otera, T.; Kubota-Kotetsu, R.; Shioda, T.; Ono, C.; Matsuura, Y.; Arase, H.; Yoshida, S.; Nakamaru, R.; Ide, R.; Tenma, A.; Kawabata, S.; Ehara, T.; Sakaguchi, M.; Tomioka, H.; Shimamura, M.; Okamoto, S.; Amaishi, Y.; Chono, H.; Mineno, J.; Komatsuno, T.; Saito, Y.; Rakugi, H.; Morishita, R.; Nakagami, H.
10.1101/2020.10.21.347799 — immunology — Posted on 2020-10-21
1569 The human brain vasculature shows a distinct expression pattern of SARS-CoV-2 entry factors
Ghobrial, M.; Charish, J.; Takada, S.; Valiante, T.; Monnier, P.; Radovanovic, I.; Bader, G.; Wälchli, T.
10.1101/2020.10.10.334664 — neuroscience — Posted on 2020-10-21
1573 Misoprostol Treatment Prevents Hypoxia-Induced Cardiac Dysfunction, Aberrant Cardiomyocyte Mitochondrial Dynamics and Permeability Transition Through Bnip3 Phosphorylation
Martens, M. D.; Seshadri, N.; Nguyen, L.; Chapman, D.; Hensen, E. S.; Xiang, B.; Mendoza, A.; Rattan, S.; Gibson, S. B.; Saleem, A. D.; Hatch, G. M.; Doucette, C. A.; Karch, J. M.; Dolinsky, V. W.; Dixon, I. M.; West, A. R.; Rampitsch, C.; Gordon, J. W.
10.1101/2020.10.09.333666 — cell biology — Posted on 2020-10-21
1574 Gulf of Mexico blue hole harbors high levels of novel microbial lineages
Patin, N. V.; Dietrich, Z. A.; Stancil, A.; Quinan, M.; Beckler, J.; Hall, E. R.; Culter, J.; Smith, C. G.; Taillefert, M.; Stewart, F. J.
10.1101/2020.10.18.342550 — microbiology — Posted on 2020-10-21
1575 Defining spatial relationships between spinal cord axons and blood vessels in hydrogel scaffolds.
Siddiqui, A. M.; Oswald, D.; Papamichalopoulos, S.; Kelly, D.; Summer, P.; Polzin, M.; Hakim, J. S.; Chen, B. K.; Yaszemski, M. J.; Windebank, A. J.; Madigan, N. N.
10.1101/788349 — neuroscience — Posted on 2020-10-21
1580 Widespread occurrence of the droplet state of proteins in the human proteome
Hardenberg, M.; Horvath, A.; Ambrus, V.; FUXREITER, M.; Vendruscolo, M.
10.1101/2020.10.21.348532 — bioinformatics — Posted on 2020-10-21
1582 Mitochondrial collapse links PFKFB3-promoted glycolysis with CLN7/MFSD8 neuronal ceroid lipofuscinosis pathogenesis
Lopez-Fabuel, I.; Garcia-Macia, M.; Buondelmonte, C.; Burmistrova, O.; Bonora, N.; Morant-Ferrando, B.; Alonso-Batan, P.; Vicente-Gutierrez, C.; Jimenez-Blasco, D.; Quintana-Cabrera, R.; Fernandez, E.; Sharaireh, A.; Guevara-Ferrer, M.; Fitzpatrick, L.; Thompton, C. D.; McKay, T. R.; Storch, S.; Medina, D. L.; Mole, S. E.; Fedichev, P. O.; Almeida, A.; Bolanos, J. P.
10.1101/2020.10.20.345314 — neuroscience — Posted on 2020-10-21
1584 The Mechanical Roles of Chaperons
Haldar, S.; chaudhuri, D.; banerjee, s.; Chakraborty, S.
10.1101/2020.10.20.346973 — biophysics — Posted on 2020-10-21
1589 YB-1 IS REQUIRED FOR THE GENESIS AND METASTATIC CAPACITY OF HUMAN BREAST CANCER
Lefort, S.; El-Naggar, A.; Tan, S.; Colborne, S.; Negri, G. L.; Pellacani, D.; Hirst, M.; Gusterson, B.; Morin, G. B.; Sorensen, P. H.; Eaves, C. J.
10.1101/372524 — cancer biology — Posted on 2020-10-21
1590 Tumor to normal single cell mRNA comparisons reveal a pan-neuroblastoma cancer cell
Kildisiute, G.; Kholosy, W. M.; Young, M. D.; Roberts, K.; Elmentaite, R.; van Hooff, S. R.; Khabirova, E.; Piapi, A.; Thevanesan, C.; Bugallo Blanco, E.; Burke, C.; Mamanova, L.; Lijnzaad, P.; Margaritis, T.; Holstege, F. C. P.; Tas, M. L.; Wijnen, M. H. W. A.; van Noesel, M. M.; del Valle, I.; Barone, G.; van der Linden, R.; Duncan, C.; Anderson, J.; Achermann, J. C.; Haniffa, M.; Teichmann, S. C. P.; Rampling, D.; Sebire, N. J.; He, X.; de Krijger, R. R.; Barker, R. A.; Meyer, K. B.; Bayraktar, O.; Straathof, K.; Molenaar, J. J.; Behjati, S.; Pacyna, C. N.; Keller, K. M.; Langenberg-Ververg
10.1101/2020.06.22.164301 — cancer biology — Posted on 2020-10-21
1595 System Identification with Biophysical Constraints: A Circuit Model of the Inner Retina
Schröder, C.; Klindt, D.; Strauss, S.; Franke, K.; Bethge, M.; Euler, T.; Berens, P.
10.1101/2020.06.16.154203 — neuroscience — Posted on 2020-10-21
1600 Rapid coordination of effective learning by the human hippocampus
Kragel, J. E.; Schuele, S.; VanHaerents, S.; Rosenow, J. M.; Voss, J. L.
10.1101/2020.10.20.347831 — neuroscience — Posted on 2020-10-21
1601 Rit2 reduces LRRK2 kinase activity and protects against alpha-synuclein neuropathology
Obergasteiger, J.; Castonguay, A.-M.; Frapporti, G.; Lobbestael, E.; Baekelandt, V.; Hicks, A.; Pramstaller, P.; Gravel, C.; Corti, C.; Levesque, M.; Volta, M.
10.1101/2020.10.21.348144 — neuroscience — Posted on 2020-10-21
1602 Genomics of Human Respiratory Syncytial Virus Vaccine Attenuation
Junier, T.; Kaiser, L.; Chaturvedi, N.; Hartert, T.; Fellay, J.
10.1101/862185 — genomics — Posted on 2020-10-21
1603 The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible initiation mechanism
Abaeva, I. S.; Vicens, Q.; Bochler, A.; Soufari, H.; Simonetti, A.; Pestova, T. V.; Hashem, Y.; Hellen, C. U. T.
10.1101/2020.10.20.347120 — molecular biology — Posted on 2020-10-21
1605 Hearing loss in Alzheimer Disease is associated with altered serum lipidomic biomarker profiles
Llano, D. A.; Issa, L.; Devanarayan, P.; Devanarayan, V. A.; Alzheimer Disease Neuroimaging Initiative,
10.1101/2020.08.15.252452 — neuroscience — Posted on 2020-10-21
1606 Live-cell imaging shows uneven segregation of extrachromosomal DNA elements and transcriptionally active extrachromosomal DNA clusters in cancer
Yi, E.; Gujar, A. D.; Guthrie, M.; Kim, H.; Johnson, K. C.; Amin, S. B.; Das, S.; Clow, P. A.; Cheng, A. W.; Verhaak, R. G.
10.1101/2020.10.20.335216 — cancer biology — Posted on 2020-10-21
1607 Interactions with stromal cells promote a more oxidized cancer cell redox state in pancreatic tumors
Datta, R.; Lau, A. N.; Sivanand, S.; Florek, L.; Wyckoff, J.; Skala, M. C.; Vander Heiden, M. G.
10.1101/2020.10.20.347658 — cancer biology — Posted on 2020-10-21
1609 Ribosome Exit Tunnel Electrostatics
Joiret, M.; Rapino, F.; Close, P.; Geris, L.
10.1101/2020.10.20.346684 — biophysics — Posted on 2020-10-21
1610 Reproducible, portable, and effcient ancient genome reconstruction with nf-core/eager
Fellows Yates, J. A.; Lamnidis, T. C.; Borry, M.; Andrades Valtuena, A.; Fagneräs, Z.; Clayton, S.; Garcia, M. U.; Neukamm, J.; Peltzer, A.
10.1101/2020.06.11.145615 — bioinformatics — Posted on 2020-10-21
1611 Stretch and Twist of HEAT Repeats Leads to Activation of DNA-PK Kinase
Chen, X.; Xu, X.; Chen, Y.; Cheung, J. C.; Wang, H.; Jiang, J.; Val, N. d.; Fox, T.; Gellert, M.; Yang, W.
10.1101/2020.10.19.346148 — biochemistry — Posted on 2020-10-21
1612 Coupling between tolerance and resistance differs between related Eimeria parasite species
Balard, A.; Jarquin-Diaz, V. H.; Jost, J.; Mittne, V.; Boehning, F.; Dureje, L.; Pialek, J.; Heitlinger, E.
10.1101/2020.01.24.918144 — evolutionary biology — Posted on 2020-10-21
1613 Zebrafish Kit ligands cooperate with erythropoietin to promote erythroid cell expansion
Oltova, J.; Svoboda, O.; Machonova, O.; Svatonova, P.; Traver, D.; Kolar, M.; Bartunek, P.
10.1101/2020.02.03.931634 — developmental biology — Posted on 2020-10-21
1614 Mechanosensitive calcium signaling in filopodia
Efremov, A. K.; Yao, M.; Sheetz, M. P.; Bershadsky, A. D.; Martinac, B.; Yan, J.
10.1101/2020.10.21.346247 — cell biology — Posted on 2020-10-21
1616 Changes in epithelial proportions and transcriptional state underlie major premenopausal breast cancer risks
Murrow, L. M.; Weber, R. J.; Caruso, J.; McGinnis, C. S.; Phong, K.; Gascard, P.; Borowsky, A. D.; Desai, T. A.; Thomson, M.; Tlsty, T. D.; Gartner, Z. J.
10.1101/430611 — systems biology — Posted on 2020-10-21
1617 Regulated compartmentalization of enzymes in Golgi by GRASP55 controls cellular glycosphingolipid profile and function
Pothukuchi, P.; Agliarulo, I.; Pirozzi, M.; Rizzo, R.; Russo, D.; Turacchio, G.; Nuchel, J.; Yang, J.-S.; Gehin, C. J. C.; Capolupo, L.; Hernandez-Corbacho, M. J.; Biswas, A.; Vanacore, G.; Dathan, N.; Nitta, T.; Henklein, P.; Thattai, M.; Inokuchi, J.-I.; Hsu, V. W.; Plomann, M.; Obeid, L. M.; Hannun, Y.; Luini, A.; D'Angelo, G.; Parashuraman, S.
10.1101/2020.05.03.074682 — cell biology — Posted on 2020-10-21
1618 Single-molecule FRET dynamics of molecular motors in an ABEL Trap
Dienerowitz, M.; Howard, J. A. L.; Quinn, S. D.; Dienerowitz, F.; Leake, M. C.
10.1101/2020.09.21.306704 — biophysics — Posted on 2020-10-21
1624 Glutamatergic neurons in the preoptic hypothalamus promote wakefulness, destabilize NREM sleep, suppress REM sleep, and regulate cortical dynamics
Mondino, A.; Hambrecht-Wiedbusch, V.; Li, D.; York, K.; Pal, D.; Gonzalez, J.; Torterolo, P.; Mashour, G. A.; Vanini, G.
10.1101/2020.10.20.347260 — neuroscience — Posted on 2020-10-21
1629 Developmental profile of psychiatric risk associated with voltage-gated cation channel activity
Clifton, N. E.; Collado Torres, L.; Burke, E. E.; Pardinas, A. F.; Harwood, J. C.; Di Florio, A.; Walters, J. T.; Owen, M. J.; O'Donovan, M. C.; Weinberger, D. R.; Holmans, P. A.; Jaffe, A. E.; Hall, J.
10.1101/2020.10.19.345801 — neuroscience — Posted on 2020-10-21
1631 Hippocampal place cells encode global location but not changes in environmental connectivity in a 4-room navigation task
Duvelle, E.; Grieves, R. M.; Liu, A.; Jedidi-Ayoub, S.; Holeniewska, J.; Harris, A.; Nyberg, N.; Donnarumma, F.; Lefort, J. M.; Jeffery, K. J.; Summerfield, C.; Pezzulo, G.; Spiers, H. J.
10.1101/2020.10.20.346130 — neuroscience — Posted on 2020-10-21
1635 Expanding diversity of Asgard archaea and the elusive ancestry of eukaryotes
Liu, Y.; Makarova, K. S.; Huang, W.-C.; Wolf, Y. I.; Nikolskaya, A.; Zhang, X.; CAI, M.; Zhang, C.-J.; Xu, W.; Luo, Z.; Cheng, L.; Koonin, E. V.; Li, M.
10.1101/2020.10.19.343400 — genomics — Posted on 2020-10-20
1637 Genetically targeted reporter imaging of deep neuronal network in the mammalian brain
Shimojo, M.; Ono, M.; Takuwa, H.; Mimura, K.; Nagai, Y.; Fujinaga, M.; Kikuchi, T.; Okada, M.; Seki, C.; Tokunaga, M.; Maeda, J.; Takado, Y.; Takahashi, M.; Minamihisamatsu, T.; Zhang, M.-R.; Tomita, Y.; Suzuki, N.; Maximov, A.; Suhara, T.; Minamimoto, T.; Sahara, N.; Higuchi, M.
10.1101/2020.04.08.032870 — neuroscience — Posted on 2020-10-20
1638 THAP1 Modulates Oligodendrocyte Maturation by Regulating ECM Degradation in Lysosomes
Yellajoshyula, D.; Pappas, S. S.; Rogers, A.; Choudhury, B.; Reed, X.; Ding, J.; Cookson, M.; Shakkottai, V.; Giger, R.; Dauer, W. T.
10.1101/2020.09.27.316133 — neuroscience — Posted on 2020-10-20
1640 Microbe-dependent heterosis in maize
Wagner, M. R.; Tang, C.; Salvato, F.; Clouse, K. M.; Bartlett, A.; Sermons, S.; Hoffmann, M.; Balint-Kurti, P. J.; Kleiner, M.
10.1101/2020.05.05.078766 — plant biology — Posted on 2020-10-20
1644 Expression analysis of photosynthesis-related genes in albino Artocarpus heterophyllus seedlings leaves
Cai, Z.; Dong, J.; Zhang, X.; Qu, Q.; Wu, F.; Cao, L.; Li, S.; Wang, Z.; Zhou, D.; Luo, J.; Yu, X.
10.1101/2020.10.20.346833 — physiology — Posted on 2020-10-20
1646 Restructuring of genomic provinces of surface ocean plankton under climate change
Fremont, P.; Gehlen, M.; Vrac, M.; Leconte, J.; Wincker, P.; Iudicone, D.; Jaillon, O.
10.1101/2020.10.20.347237 — ecology — Posted on 2020-10-20
1647 Satellite subgenomic particles are key regulators of adeno-associated virus life cycle
Zhang, J.; Guo, P.; Yu, X.; Lee, K.; Firrman, J.; Chrzanowski, M.; Chen, K.; Chen, X.; Pouchnik, D.; Diao, Y.; Samulski, R. J.; Xiao, W.
10.1101/2020.10.20.346957 — molecular biology — Posted on 2020-10-20
1648 A Boolean Model of the Formation of Tumour Associated Macrophages in an in-vitro Model of Chronic Lymphocytic Leukaemia
Marku, M.; Raynal, F.; Verstraete, N.; Domagala, M.; Madrid-Mencia, M.; Poupot, M.; Fournie, J.-J.; Ysebaert, L.; Pancaldi, V.
10.1101/2020.10.14.337642 — systems biology — Posted on 2020-10-20
1649 Restricted differentiative capacity of Wt1-expressing peritoneal mesothelium in postnatal and adult mice.
Wilm, T. P.; Tanton, H.; Mutter, F.; Foisor, V.; Middlehurst, B.; Ward, K.; Benameur, T.; Hastie, N.; Wilm, B.
10.1101/2020.08.21.257154 — pathology — Posted on 2020-10-20
1652 "Select and retrieve via direct upsampling" network (SARDU-Net): a data-driven, model-free, deep learning approach for quantitative MRI protocol design
Grussu, F.; Blumberg, S. B.; Battiston, M.; Kakkar, L. S.; Lin, H.; Ianus, A.; Schneider, T.; Singh, S.; Bourne, R.; Punwani, S.; Atkinson, D.; Gandini Wheeler-kingshott, C. A. M.; Panagiotaki, E.; Mertzanidou, T.; Alexander, D. C.
10.1101/2020.05.26.116491 — bioengineering — Posted on 2020-10-20
1656 Expanding diversity of Asgard archaea and the elusive ancestry of eukaryotes
Liu, Y.; Makarova, K. S.; Huang, W.-C.; Wolf, Y. I.; Nikolskaya, A.; Zhang, X.; CAI, M.; Zhang, C.-J.; Xu, W.; Luo, Z.; Cheng, L.; Koonin, E. V.; Li, M.
10.1101/2020.10.19.343400 — genomics — Posted on 2020-10-20
1658 Droplet printing reveals the importance of micron-scale structure for bacterial ecology
Krishna Kumar, R.; Meiller-Legrand, T.; Alcinesio, A.; Gonzalez, D.; Mavridou, D. A. I.; Meacock, O. J.; Smith, W. P. J.; Zhou, L.; Kim, W.; Pulcu, G. S.; Bayley, H.; Foster, K. R.
10.1101/2020.10.20.346577 — microbiology — Posted on 2020-10-20
1660 Control of archetype BK polyomavirus miRNA expression
Imperiale, M. J.; Zou, W.; Vue, G. S.; Manza, H.; Assetta, B.; Atwood, W. J.
10.1101/2020.10.20.347229 — microbiology — Posted on 2020-10-20
1661 Multi-omic Single-cell Atlas Reveals Broad Ex Vivo Effects on Human Immunobiology
Savage, A. K.; Gutschow, M. V.; Chiang, T.; Henderson, K.; Green, R.; Chaudhari, M.; Swanson, E.; Heubeck, A. T.; Kondza, N.; Burley, K. C.; Genge, P. C.; Lord, C.; Smith, T.; Beaubien, A.; Goldy, J.; Bolouri, H.; Buckner, J. H.; Meijer, P.; Coffey, E. M.; Li, X.-j.; Skene, P. J.; Torgerson, T. R.; Bumol, T. F.
10.1101/2020.10.18.344663 — immunology — Posted on 2020-10-20
1664 An approach for long-term, multi-probe Neuropixels recordings in unrestrained rats
Luo, T. Z.; Bondy, A. G.; Gupta, D.; Elliott, V. A.; Kopec, C. D.; Brody, C. D.
10.1101/2020.04.13.039305 — neuroscience — Posted on 2020-10-20
1668 Anatomical modeling of brain vasculature in two-photon microscopy by generalizable deep learning
Tahir, W.; Kura, S.; Zhu, J.; Cheng, X.; Damseh, R.; Tadesse, F.; Seibel, A.; Lee, B. S.; Lesage, F.; Sakadzic, S.; Boas, D. A.; Tian, L.
10.1101/2020.08.09.243394 — neuroscience — Posted on 2020-10-20
1669 Dual-mechanism estrogen receptor inhibitors expand the repertoire of anti-hormone therapy for breast cancer
Min, J.; Nwachukwu, J. C.; Rangarajan, E.; Nettles, C. C.; Min, C.; Sanabria Guillen, V.; Ziegler, Y.; Yan, S.; Carlson, K.; Hou, Y.; Kim, S. H.; Novick, S.; Pascal, B.; Houtman, R.; Griffin, P.; Izard, T.; Katzenellenbogen, B.; Katzenellenbogen, J. A.; Nettles, K. W.
10.1101/2020.07.06.189977 — cancer biology — Posted on 2020-10-20
1671 Therapy-induced senescence in normal tissue promotes breast cancer metastasis
Perkins, D. W.; Haider, S.; Roberston, D.; Buus, R.; O'Leary, L.; Isacke, C. M.
10.1101/2020.10.17.343590 — cancer biology — Posted on 2020-10-20
1672 Chemotactic Migration of Bacteria in Porous Media
Bhattacharjee, T.; Amchin, D. B.; Ott, J. A.; Kratz, F.; Datta, S. S.
10.1101/2020.08.10.244731 — biophysics — Posted on 2020-10-20
1674 Membrane-Dependent Amyloid Aggregation of Human BAX α9 (173-192)
Price, D. A.; Hill, T. D.; Hutson, K. A.; Rightnowar, B. W.; Moran, S. D.
10.1101/2020.10.20.347567 — biochemistry — Posted on 2020-10-20
1676 Enteric viruses evoke broad host immune responses resembling bacterial microbiome
Dallari, S.; Heaney, T.; Rosas-Villegas, A.; Neil, J. A.; Wong, S.-Y.; Brown, J. J.; Urbanek, K.; Dermody, T.; Cadwell, K.
10.1101/2020.10.20.347286 — microbiology — Posted on 2020-10-20
1682 In vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169 in multiple routes of transmission
Haugh, K. A.; Ladinsky, M. S.; Ullah, I.; Pi, R.; Gilardet, A.; Kumar, P.; Bjorkman, P.; Mothes, W.; Uchil, P. D.
10.1101/2020.10.20.347427 — microbiology — Posted on 2020-10-20
1687 Genomic rearrangements uncovered by genome-wide co-evolution analysis of a major nosocomial pathogen Enterococcus faecium
Top, J.; Arredondo Alonso, S.; Schurch, A. C.; Puranen, S.; Pesonen, M.; Pensar, J.; Willems, R. J.; Corander, J.
10.1101/2020.10.20.346924 — genomics — Posted on 2020-10-20
1688 Local adaptation in populations of Mycobacterium tuberculosis endemic to the Indian Ocean Rim
Menardo, F.; Rutaihwa, L. K.; Zwyer, M.; Borrell, S.; Comas, I.; Conceicao, E. C.; Coscolla, M.; Cox, H.; Joloba, M.; Dou, H.-Y.; Feldmann, J.; Fenner, L.; Fyfe, J.; Gao, Q.; de Viedma, D. G.; Garcia-Basteiro, A. L.; Gygli, S. M.; Hella, J.; Hiza, H.; Jugheli, L.; Kamwela, L.; Kato-Maeda, M.; Liu, Q.; Ley, S. D.; Loiseau, C.; Mahasirimongkol, S.; Malla, B.; Palittapongarnpim, P.; Rakotosamimanana, N.; Rasolofo, V.; Reinhard, M.; Reither, K.; Sasamalo, M.; Duarte, R. S.; Sola, C.; Suffys, P.; Batista Lima, K. V.; Yeboah-Manu, D.; Beisel, C.; Brites, D.; Gagneux, S.
10.1101/2020.10.20.346866 — genomics — Posted on 2020-10-20
1689 Inverse oculomotor responses of achiasmatic mice expressing a transfer-defective Vax1 mutant
Min, K. W.; Kim, N.; Lee, J. H.; Sung, Y.; Kim, M.; Lee, E. J.; Kim, J.-H.; Lee, J.; Kim, J.-M.; Yang, J. M.; Lee, S.-H.; Lee, H.-W.; Kim, J. W.
10.1101/2020.10.20.346551 — developmental biology — Posted on 2020-10-20
1690 Naegleria fowleri: protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba
Barret, K.; Tillery, L.; Goldstein, J.; Lassner, J. W.; Osterhout, B.; Tran`, N. L.; Xu, L.; Young, R.; Craig, J.; Chun, I.; Dranow, D. M.; Abendroth, J.; Delker, S. L.; Davies, D. R.; Mayclin, S. J.; Calhoun, B.; Bolejack, M. J.; Staker, B.; Subramanian, S.; Phan, I. Q.; Lorimer, D. D.; Myler, P. J.; Edwards, T. E.; Kyle, D. E.; Rice, C. A.; Morris, J.; Leahy, J. W.; Manetsch, R.; Barrett, L. K.; Van Voorhis, W.
10.1101/2020.10.20.327296 — molecular biology — Posted on 2020-10-20
1692 Ceragenins and antimicrobial peptides kill bacteria through distinct mechanisms
Mitchell, G.; Silvis, M. R.; Talkington, K. C.; Budzik, J. M.; Dodd, C. E.; Paluba, J. M.; Oki, E. A.; Trotta, K. L.; Licht, D. J.; Jimenez-Morales, D.; Chou, S.; Savage, P. B.; Gross, C. A.; Marletta, M. A.; Cox, J. S.
10.1101/2020.10.20.346411 — microbiology — Posted on 2020-10-20
1694 A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit
Schedlbauer, A.; Iturrioz, I.; Ochoa-Lizarralde, B.; Diercks, T.; Lopez-Alonso, J. P.; Lavin, J. L.; Kaminishi, T.; Capuni, R.; Dhimole, N.; de Astigarraga, E.; Gil-Carton, D.; Fucini, P.; Connell, S. R.
10.1101/2020.10.19.334821 — microbiology — Posted on 2020-10-20
1697 Impact of clade specific mutations on structural fidelity of SARS-CoV-2 proteins
Basu, S.; Mukhopadhyay, S.; Das, R.; Mukhopadhyay, S.; Singh, P. K.; Ganguli, S.
10.1101/2020.10.20.347021 — bioinformatics — Posted on 2020-10-20
1702 A novel Golgi-associated Vangl2 translational variant required for PCP regulation in vertebrates
Walton, A.; Revinski, D.; Serge, A.; Audebert, S.; Camoin, L.; Puvirajesinghe, T. M.; Isnardon, D.; Marchetto, S.; Kodjabachian, L.; Bailly, E.; Borg, J.-P.
10.1101/2020.10.20.347385 — cell biology — Posted on 2020-10-20
1703 Hypothalamic NMDA receptors stabilize NREM sleep and are essential for REM sleep
Miracca, G.; Anuncibay Soto, B.; Tossell, K.; Yustos, R.; Vyssotski, A. L.; Franks, N. P.; Wisden, W.
10.1101/2020.10.19.345728 — neuroscience — Posted on 2020-10-20
1704 The cell cycle state defines TACC3 as a regulator gene in glioblastoma
Briggs, H.; Polson, E.; Irving, B. K.; Zougman, A.; Mathew, R. K.; Gendoo, D. M.; Wurdak, H.
10.1101/2020.10.20.346643 — cancer biology — Posted on 2020-10-20
1706 CellRank for directed single-cell fate mapping
Lange, M.; Bergen, V.; Klein, M.; Setty, M.; Reuter, B.; Bakhti, M.; Lickert, H.; Ansari, M.; Schniering, J.; Schiller, H. B.; Pe'er, D.; Theis, F. J.
10.1101/2020.10.19.345983 — bioinformatics — Posted on 2020-10-20
1708 On the Emergence of P-Loop NTPase and Rossmann Enzymes from a Beta-Alpha-Beta Ancestral Fragment
Longo, L. M.; Jablonska, J.; Vyas, P.; Kanade, M.; Kolodny, R.; Ben-Tal, N.; Tawfik, D. S.
10.1101/2020.07.15.204123 — evolutionary biology — Posted on 2020-10-20
1710 Pharmacological CDK4/6 inhibition unravels a p53-induced secretory phenotype in senescent cells
Wang, B.; Brandenburg, S.; Hernandez-Segura, A.; van Vliet, T.; Jongbloed, E. M.; Wilting, S. M.; Ohtani, N.; Jager, A.; Demaria, M.
10.1101/2020.06.05.135715 — cell biology — Posted on 2020-10-20
1711 Single-cell RNA-sequencing reveals dysregulation of molecular programs associated with SARS-CoV-2 severity and outcomes in patients with chronic lung disease
Bui, L. T.; Winters, N. I.; Chung, M.-I.; Joseph, C.; Gutierrez, A. J.; Habermann, A. C.; Adams, T. S.; Schupp, J. C.; Poli, S.; Peter, L. M.; Taylor, C. J.; Blackburn, J. B.; Richmond, B. W.; Nicholson, A. G.; Rassl, D.; Wallace, W. A.; Rosas, I. O.; Jenkins, R. G.; Kaminski, N.; Kropski, J. A.; Banovich, N. E.; Human Cell Atlas Lung Biological Network,
10.1101/2020.10.20.347187 — cell biology — Posted on 2020-10-20
1712 A lamin A/C variant causing striated muscle disease provides insights into filament organization
Medalia, O.; Kronenberg-Tenga, R.; Tatli, M.; Eibauer, M.; Wu, W.; Shin, J.-Y.; Bonne, G.; Worman, H. J.
10.1101/2020.10.20.347088 — cell biology — Posted on 2020-10-20
1715 High-throughput detection of antibodies targeting the SARS-CoV-2 Spike in longitudinal convalescent plasma samples
Anand, S. P.; Prevost, J.; Richard, J.; Perreault, J.; Tremblay, T.; Drouin, M.; Fournier, M.-J.; Lewin, A.; Bazin, R.; Finzi, A.
10.1101/2020.10.20.346783 — microbiology — Posted on 2020-10-20
1716 Isolation of cross-reactive monoclonal antibodies against divergent human coronaviruses that delineate a conserved and vulnerable site on the spike protein
Wang, C.; van Haperen, R.; Gutierrez-Alvarez, J.; Li, W.; Okba, N.; Albulescu, I.; Widjaja, I.; van Dieren, B.; Fernandez-Delgado, R.; Sola, I.; Hurdiss, D.; Daramola, O.; Grosveld, F.; van Kuppeveld, F.; Haagmans, B.; Enjuanes, L.; Drabek, D.; Bosch, B.-J.
10.1101/2020.10.20.346916 — microbiology — Posted on 2020-10-20
1718 Zebrafish studies on the vaccine candidate to COVID-19, the Spike protein: Production of antibody and adverse reaction
Fernandes, B. H. V.; Feitosa, N. M.; Barbosa, A. P.; Bomfim, C. G.; Garnique, A. M.; Gomes, F. I.; Nakajima, R. T.; Belo, M. A.; Eto, S. F.; Fernandes, D. C.; Malafaia, G.; Manrique, W. G.; Conde, G.; Rosales, R. R.; Todeschini, I.; Rivero, I.; Llontop, E.; Sgro, G. G.; Oka, G. U.; Bueno, N. F.; Ferraris, F. K.; de Magalhaes, M. T.; Medeiros, R. J.; Gomes, J. M.; Junqueira, M. S.; Conceicao, K.; Pontes, L. G.; Neto, A. C.; Perez, A. C.; Barcellos, L. G.; Junior, J. D. C.; Dorlass, E. G.; Camara, N. O.; Durigon, E. L.; Cunha, F. Q.; Nobrega, R. H.; Machado-Santelli, G. M.; Farah, C. S.; Veras,
10.1101/2020.10.20.346262 — immunology — Posted on 2020-10-20
1719 APOE4 Lowers Energy Expenditure and Impairs Glucose Oxidation by Increasing Flux through Aerobic Glycolysis
Farmer, B. C.; Williams, H. C.; Devanney, N. A.; Piron, M. A.; Nation, G. K.; Carter, D. J.; Walsh, A. E.; Khanal, R.; Young, L. E. A.; Kluemper, J. C.; Hernandez, G.; Allenger, E. J.; Mooney, R.; Brandon, J. A.; Gupta, V. A.; Kern, P. A.; Gentry, M. S.; Morganti, J. M.; Sun, R. C.; Johnson, L. A.
10.1101/2020.10.19.345991 — neuroscience — Posted on 2020-10-20
1720 A fluorescent sensor for spatiotemporally resolved endocannabinoid dynamics in vitro and in vivo
Dong, A.; He, K.; Dudok, B.; Farrell, J. S.; Guan, W.; Liput, D. J.; Puhl, H. L.; Cai, R.; Duan, J.; Albarran, E.; Ding, J.; Lovinger, D. M.; Li, B.; Soltesz, I.; Li, Y.
10.1101/2020.10.08.329169 — neuroscience — Posted on 2020-10-20
1722 SciSight: Combining faceted navigation and research group detection for COVID-19 exploratory scientific search
Hope, T.; Portenoy, J.; Vasan, K.; Borchardt, J.; Horvitz, E.; Weld, D. S.; Hearst, M. A.; West, J.
10.1101/2020.05.23.112284 — bioinformatics — Posted on 2020-10-20
1724 Short- and long-read metagenomics of South African gut microbiomes reveal a transitional composition and novel taxa
Tamburini, F. B.; Maghini, D.; Oduaran, O. H.; Brewster, R.; Hulley, M. R.; Sahibdeen, V.; Norris, S. A.; Tollman, S.; Kahn, K.; Wagner, R.; Wade, A. N.; Wafawanaka, F.; Gomez-Olive, X.; Twine, R.; Lombard, Z.; Hazelhurst, S.; Bhatt, A. S.
10.1101/2020.05.18.099820 — genomics — Posted on 2020-10-20
1726 Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysis
Bull, R. A.; Adikari, T.; Ferguson, J. M.; Hammond, J. M.; Stevanovski, I.; Beukers, A. G.; Naing, Z.; Yeang, M.; Verich, A.; Gamaarachichi, H.; Kim, K. W.; Luciani, F.; Stelzer-Braid, S.; Eden, J.-S.; Rawlinson, W. D.; van Hal, S. J.; Deveson, I. W.
10.1101/2020.08.04.236893 — genomics — Posted on 2020-10-20
1727 White matter brain aging In Relationship to Schizophrenia and Its Cognitive Deficit
Wang, J.; Kochunov, P.; Sampath, H.; Hatch, K. S.; Ryan, M. C.; Xue, F.; Neda, J.; Paul, T.; Hahn, B.; Gold, J.; Waltz, J.; Hong, L. E.; Chen, S.
10.1101/2020.10.19.344879 — neuroscience — Posted on 2020-10-20
1729 SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 are Expressed in the Pancreas but are Not Enriched in Islet Endocrine Cells
Coate, K. C.; Cha, J.; Shrestha, S.; Wang, W.; Goncalves, L. M.; Almaca, J.; Kapp, M. E.; Fasolino, M.; Morgan, A.; Dai, C.; Saunders, D. C.; Bottino, R.; Aramandla, R.; Jenkins, R.; Stein, R.; Kaestner, K. H.; Vahedi, G.; Brissova, M.; Powers, A. C.
10.1101/2020.08.31.275719 — cell biology — Posted on 2020-10-20
1730 Pre-clinical search of SARS-CoV-2 inhibitors and their combinations in approved drugs to tackle COVID-19 pandemic
Rodon, J.; Munoz-Basagoiti, J.; Perez-Zsolt, D.; Noguera-Julian, M.; Paredes, R.; Mateu, L.; Quinones, C.; Erkizia, I.; Blanco, I.; Valencia, A.; Guallar, V.; Carrillo, J.; Blanco, J.; Segales, J.; Clotet, B.; Vergara-Alert, J.; Izquierdo-Useros, N.
10.1101/2020.04.23.055756 — microbiology — Posted on 2020-10-20
1731 Conserved cholesterol-related activities of Dispatched drive Sonic hedgehog shedding from the cell membrane
Grobe, K.; Ehring, K.; Manikowski, D.; Froese, J.; Jakobs, P.; Gude, F.; Rescher, U.; Goretzko, J.
10.1101/2020.10.19.346395 — cell biology — Posted on 2020-10-20
1732 Neural oscillations track natural but not artificial fast speech: Novel insights from speech-brain coupling using MEG
Hincapie Casas, A. S.; Lajnef, T.; Guiraud, H.; Laaksonen, H.; Bayle, D.; Jerbi, K.; Boulenger, V.
10.1101/2020.10.20.344895 — neuroscience — Posted on 2020-10-20
1733 Large, stable spikes exhibit differential broadening in excitatory and inhibitory neocortical boutons
Ritzau-Jost, A.; Tsintsadze, T.; Krueger, M.; Ader, J.; Bechmann, I.; Eilers, J.; Barbour, B.; Smith, S. M.; Hallermann, S.
10.1101/2020.10.19.346346 — neuroscience — Posted on 2020-10-20
1734 eEF1A2 controls local translation and actin dynamics in structural synaptic plasticity
Mendoza, M. B.; Gutierrez, S.; Ortiz, R.; Moreno, D. F.; Dermit, M.; Dodel, M.; Rebollo, E.; Bosch, M.; Mardakheh, F. K.; Gallego, C.
10.1101/2020.10.20.346858 — neuroscience — Posted on 2020-10-20
1735 Dendritic spines are lost in clusters in patients with Alzheimers disease
Mijalkov, M.; Volpe, G.; Fernaud-Espinosa, I.; DeFelipe, J.; B. Pereira, J.; Merino-Serrais, P.
10.1101/2020.10.20.346718 — neuroscience — Posted on 2020-10-20
1736 Genome-wide patterns of de novo tandem repeat mutations and their contribution to autism spectrum disorders.
Mitra, I.; Huang, B.; Mousavi, N.; Ma, N.; Lamkin, M.; Yanicky, R.; Shleizer-Burko, S.; Lohmueller, K. E.; Gymrek, M.
10.1101/2020.03.04.974170 — genomics — Posted on 2020-10-20
1737 Surface electrostatics govern the emulsion stability of biomolecular condensates
Welsh, T. J.; Krainer, G.; Espinosa, J. R.; Joseph, J. A.; Sridhar, A.; Jahnel, M.; Arter, W. E.; Saar, K. L.; Alberti, S.; Collepardo-Guevara, R.; Knowles, T. P. J.
10.1101/2020.04.20.047910 — biophysics — Posted on 2020-10-20
1738 MALVIRUS: an integrated web application for viral variant calling
Ciccolella, S.; Denti, L.; Bonizzoni, P.; Della Vedova, G.; Pirola, Y.; Previtali, M.
10.1101/2020.05.05.076992 — bioinformatics — Posted on 2020-10-20
1739 Structural impact on SARS-CoV-2 spike protein by D614G substitution
Zhang, J.; Cai, Y.; Xiao, T.; Lu, J.; Peng, H.; Sterling, S. M.; Walsh, R. M.; Rits-Volloch, S.; Sliz, P.; Chen, B.
10.1101/2020.10.13.337980 — biochemistry — Posted on 2020-10-20
1740 Highly diverse mesophotic reef fish communities in Raja Ampat, West Papua
Andradi-Brown, D. A.; Beer, A. J. E.; Colin, L.; Hastuti, ; Head, C. E. I.; Hidayat, N. I.; Lindfield, S. J.; Mitchell, C. R.; Pada, D. N.; Piesinger, N. M.; Purwanto, ; Ahmadia, G. N.
10.1101/640490 — ecology — Posted on 2020-10-20
1741 Structure of a transcribing RNA polymerase II-U1 snRNP complex
Zhang, S.; Aibara, S.; Vos, S. M.; Agafonov, D. E.; Lührmann, R.; Cramer, P.
10.1101/2020.10.19.344200 — molecular biology — Posted on 2020-10-20
1742 Stem bending generates electrical response in poplar
Tinturier, E.; Leblanc-Fournier, N.; Badel, E.; Julien, J.-L.
10.1101/2020.10.19.345959 — plant biology — Posted on 2020-10-20
1743 Precision of Tissue Patterning is Controlled by Dynamical Properties of Gene Regulatory Networks
Exelby, K.; Herrera-Delgado, E.; Garcia Perez, L.; Perez-Carrasco, R.; Sagner, A.; Metzis, V.; Sollich, P.; Briscoe, J.
10.1101/721043 — developmental biology — Posted on 2020-10-20
1744 Child abuse associates with increased recruitment of perineuronal nets in the ventromedial prefrontal cortex: evidence for an implication of oligodendrocyte progenitor cells
Tanti, A.; Belliveau, C.; Nagy, C.; Maitra, M.; Denux, F.; Perlman, K.; Chen, F.; Mpai, R.; Canonne, C.; Davoli, M. A.; Turecki, G.; Mechawar, N.
10.1101/2020.10.19.345355 — neuroscience — Posted on 2020-10-20
1745 Hierarchical imaging and computational analysis of three-dimensional vascular network architecture in the entire postnatal and adult mouse brain
Wälchli, T.; Bisschop, J.; Miettinen, A.; Ulmann-Schuler, A.; Hintermueller, C.; Meyer, E. P.; Krucker, T.; Wälchli, R.; Monnier, P.; Carmeliet, P.; Vogel, J.; Stampanoni, M.
10.1101/2020.10.19.344903 — neuroscience — Posted on 2020-10-20
1746 Meiosis and Kinetochore genes are used by cancer cells as genome destabilizers and transformation catalysts
Thapa, R.; Vasudevan, S.; Abo-Ayoub Ashqar, M.; Reich, E.; Kravchenko-Balasha, N.; Klutstein, M.
10.1101/826081 — cancer biology — Posted on 2020-10-20
1747 Mitochondrial membrane tension governs fission
Mahecic, D.; Carlini, L.; Kleele, T.; Colom, A.; Goujon, A.; Matile, S.; Roux, A.; Manley, S.
10.1101/255356 — biophysics — Posted on 2020-10-20
1750 The genomic and transcriptomic foundations of viviparous seed development in mangroves
Qiao, H.; Zhou, X.; Su, W.; Jin, P.; Zhao, X.; He, S.; Hu, W.; Fu, M.; Yu, D.; Hao, S.; Zhang, Y.-Y.; Wang, W.; Ye, C.; Li, Q. Q.; Shen, Y.
10.1101/2020.10.19.346163 — genomics — Posted on 2020-10-20
1751 Expanding diversity of Asgard archaea and the elusive ancestry of eukaryotes
Liu, Y.; Makarova, K. S.; Huang, W.-C.; Wolf, Y. I.; Nikolskaya, A.; Zhang, X.; CAI, M.; Zhang, C.-J.; Xu, W.; Luo, Z.; Cheng, L.; Koonin, E. V.; Li, M.
10.1101/2020.10.19.343400 — genomics — Posted on 2020-10-20
1753 Juvenile corals inherit mutations acquired during the parents lifespan
Vasquez-Kuntz, K. L.; Kitchen, S. A.; Conn, T. L.; Vohsen, S. A.; Chan, A. N.; Vermeij, M. J.; Page, C.; Marhaver, K. L.; Baums, I. B.
10.1101/2020.10.19.345538 — evolutionary biology — Posted on 2020-10-20
1764 Cross-validation of technologies for genotyping CYP2D6 and CYP2C19
Carvalho Henriques, B.; Buchner, A.; Hu, X.; Yavorskyy, V.; Wang, Y.; Martens, K.; Carr, M.; Behroozi Asl, B.; Hague, J.; Maier, W.; Dernovsek, M. Z.; Henigsberg, N.; Souery, D.; Cattaneo, A.; Hauser, J.; Mors, O.; Rietschel, M.; Pfeffer, G.; Bousman, C.; Aitchison, K. J.
10.1101/2019.12.24.870295 — genetics — Posted on 2020-10-19
1765 Internalization of the host alkaline pH signal in a fungal pathogen
Brown, H. E.; Alspaugh, J. A.; Pianalto, K. M.; Mueller, K. D.; Fernandes, C. M.; Del Poeta, M.
10.1101/2020.10.19.345280 — cell biology — Posted on 2020-10-19
1767 Multi-modal imaging of a single postmortem mouse brain over five orders of magnitude of resolution
Foxley, S.; Sampathkumar, V.; De Andrade, V.; Trinkle, S.; Sorokina, A.; Norwood, K.; La Riviere, P.; Kasthuri, N.
10.1101/2020.10.07.329789 — neuroscience — Posted on 2020-10-19
1769 Newly isolated sporopollenin microcages from Cedrus libani and Pinus nigra for controlled delivery of Oxaliplatin
Mujtaba, M.; Yılmaz, B. A.; Cansaran Duman, D.; Akyuz, L.; Yangın, S.; Kaya, M.; Ceter, T.; Khawar, K. M.
10.1101/2020.10.19.345157 — pharmacology and toxicology — Posted on 2020-10-19
1770 A drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent local relapse and treat established brain metastasis
Zhu, L.; Yebra, N.; Retana, D.; Miarka, L.; Hernandez-Encinas, E.; Blanco-Aparicio, C.; Martinez, S.; Soffietti, R.; Bertero, L.; Cassoni, P.; Weiss, T.; Munoz, J.; Sepulveda, J. M.; Perez-Nunez, A.; Hernandez-Lain, A.; Ruano, Y.; Toldos, O.; Caleiras, E.; Megias, D.; Grana-Castro, O.; Nör, C.; Taylor, M. D.; Cusso, L.; Desco, M.; Weller, M.; Pastor, J.; Valiente, M.
10.1101/2020.10.16.329243 — cancer biology — Posted on 2020-10-19
1772 Utilization and prospectus of non-timber forest products as livelihood materials
Das, A. K.; Ashaduzzaman, M.; Islam, M. N.; Atanu Kumar Das, Md. Asaduzzaman, Md Nazrul Islam,
10.1101/2020.10.19.345223 — bioengineering — Posted on 2020-10-19
1780 Prenatal Environmental Stressors Impair Postnatal Microglia Function and Adult Behavior in Males
Block, C. L.; Eroglu, O.; Mague, S. D.; Sriworarat, C.; Blount, C.; Malacon, K. E.; Beben, K. A.; Ndubuizu, N.; Talbot, A.; Gallagher, N.; Jo, Y. C.; Nyangacha, T.; Carlson, D.; Dzirasa, K.; Eroglu, C.; Bilbo, S. D.
10.1101/2020.10.15.336669 — neuroscience — Posted on 2020-10-19
1783 PELP1/SRC-3-dependent regulation of metabolic kinases drives therapy resistant ER+ breast cancer
Truong, T. H.; Benner, E. A.; Hagen, K. M.; Temiz, N. A.; Perez Kerkvliet, C.; Wang, Y.; Cortes-Sanchez, E.; Yang, C.-H.; Pengo, T.; Guillen, K. P.; Welm, B. W.; Telang, S.; Lange, C. A.; Ostrander, J. H.
10.1101/2020.08.07.238550 — cancer biology — Posted on 2020-10-19
1786 Teleoperation of an ankle-foot prosthesis with a wrist exoskeleton
Welker, C. G.; Chiu, V. L.; Voloshina, A. S.; Collins, S. H.; Okamura, A. M.
10.1101/2020.07.17.209049 — bioengineering — Posted on 2020-10-19
1787 Investigation of biochemical changes in barley inoculated with Trichoderma harzianum T-22 under salt stress
Gupta, S.; Smith, P. M. C.; Boughton, B. A.; Rupasinghe, T.; Natera, S. H. A.; Roessner, U.
10.1101/2020.10.19.346056 — biochemistry — Posted on 2020-10-19
1790 Chromatin conformation capture (Hi-C) sequencing of patient-derived xenografts: analysis guidelines
Dozmorov, M. G.; Tyc, K. M.; Sheffield, N. C.; Boyd, D. C.; Olex, A. L.; Reed, J.; Harrell, J. C.
10.1101/2020.10.17.343814 — genomics — Posted on 2020-10-19
1795 Landscape of allele-specific transcription factor binding in the human genome
Abramov, S.; Boytsov, A.; Bykova, D.; Penzar, D. D.; Yevshin, I.; Kolmykov, S. K.; Fridman, M. V.; Favorov, A. V.; Vorontsov, I. E.; Baulin, E.; Kolpakov, F.; Makeev, V. J.; Kulakovskiy, I. V.
10.1101/2020.10.07.327643 — genetics — Posted on 2020-10-19
1796 A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: from genomic characterization to high-throughput field detection
Cattel, J.; Haberkorn, C.; Laporte, F.; Gaude, T.; Cumer, T.; Renaud, J.; Sutherland, I. W.; Hertz, J. C.; Bonneville, J.-M.; Arnaud, V.; Nous, C.; Fustec, B.; Boyer, S.; Marcombe, S.; David, J.-P.
10.1101/2020.06.08.139741 — evolutionary biology — Posted on 2020-10-19
1797 Global change adaptation reduces plasticity and limits future resilience
Brennan, R. S.; deMayo, J. A.; Dam, H. G.; Finiguerra, M.; Baumann, H.; Pespeni, M. H.
10.1101/2020.01.29.925396 — evolutionary biology — Posted on 2020-10-19
1799 Mitochondrial fission governed by Drp1 regulates exogenous fatty acid usage and storage
Song, J. E.; Alves, T.; Stutz, B.; Sestan-Pesa, M.; Kilian, N.; Diano, S.; Kibbey, R.; Horvath, T.
10.1101/2020.10.17.343616 — cell biology — Posted on 2020-10-19
1800 Lentiviral vectors transduce lung stem cells without disrupting plasticity
Cooney, A. L.; Thurman, A. L.; McCray, P. B.; Pezzulo, A. A.; Sinn, P. L.
10.1101/2020.10.19.345611 — molecular biology — Posted on 2020-10-19
1801 Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules
Shams, A.; Higgins, S. A.; Fellmann, C.; Laughlin, T. J.; Oakes, B. L.; Lew, R.; Lukarska, M.; Arnold, M.; Staahl, B.; Doudna, J. A.; Savage, D.
10.1101/2020.10.19.344077 — molecular biology — Posted on 2020-10-19
1802 Single cell resolution of SARS-CoV-2 tropism, antiviral responses, and susceptibility to therapies in primary human airway epithelium
Fiege, J. K.; Thiede, J. M.; Nanda, H.; Matchett, W. E.; Moore, P. J.; Montanari, N. R.; Thielen, B. K.; Daniel, J.; Stanley, E.; Hunter, R. C.; Menachery, V. D.; Shen, S. S.; Bold, T. D.; Langlois, R. A.
10.1101/2020.10.19.343954 — microbiology — Posted on 2020-10-19
1807 Cyclic-di-GMP induces STING-dependent ILC2 to ILC1 shift during innate type 2 lung inflammation
Cavagnero, K. J.; Doherty, T. A.; Badrani, J. H.; Naji, L. H.; Lacasa, L. D.; Strohm, A. N.; Amadeo, M. B.; Leng, A. S.
10.1101/2020.10.19.345850 — immunology — Posted on 2020-10-19
1810 Nucleus Basalis Stimulation Enhances Working Memory by Stabilizing Attractor Networks in Prefrontal Cortex
Qi, X.-L.; Liu, R.; Singh, B.; Bestue, D.; Compte, A.; Vazdarjanova, A. I.; Blake, D. T.; Constantinidis, C.
10.1101/674465 — neuroscience — Posted on 2020-10-19
1812 Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity, and memory in mouse models of Alzheimer's disease
Oliveira, M. M.; Lourenco, M. V.; Longo, F.; Kasica, N. P.; Yang, W.; Ureta, G.; Ferreira, D. D. P.; Mendonca, P. H. J.; Bernales, S.; Ma, T.; De Felice, F. G.; Klann, E.; Ferreira, S. T.
10.1101/2020.10.19.344564 — neuroscience — Posted on 2020-10-19
1818 To pool or not to pool: Can we ignore cross-trial variability in FMRI?
Chen, G.; Padmala, S.; Chen, Y.; Taylor, P. A.; Cox, R. W.; Pessoa, L.
10.1101/2020.05.19.102111 — neuroscience — Posted on 2020-10-19
1819 griPASTA: A hacked kitchen scale for quantification of grip strength in rodents
Homolak, J.; Virag, D.; Kodvanj, I.; Matak, I.; Babic Perhoc, A.; Knezovic, A.; Osmanovic Barilar, J.; Trkulja, V.; Salkovic-Petrisic, M.
10.1101/2020.07.23.217737 — neuroscience — Posted on 2020-10-19
1820 Pore constrictions in intervessel pit membranes reduce the risk of embolism spreading in angiosperm xylem
Kaack, L.; Weber, M.; Isasa, E.; Karimi, Z.; Li, S.; Pereira, L.; Trabi, C. L.; Zhang, Y.; Schenk, H. J.; Schuldt, B.; Schmidt, V.; Jansen, S.
10.1101/2020.10.19.345413 — plant biology — Posted on 2020-10-19
1823 MiRNA-223 Inhibits MouseGallstone Formation by Targeting Key Transporters in Hepatobiliary Cholesterol Secretion Pathway
Zhao, F.; Ma, S.; Shen, W.; Li, Y.; Peng, Z.; Cui, X.; Xing, L.; Li, X.; Liu, G.; Jin, L.; Ma, T.; Shi, L.
10.1101/2020.10.19.344580 — pathology — Posted on 2020-10-19
1825 CXCR4 signaling is counteracted by the naturally occurring CXCR4 antagonist EPI-X 4 in Waldenstrom Macroglobulinemia
Kaiser, L. M.; Harms, M.; Sauter, D.; Rawat, V. P.; Glitscher, M.; Hildt, E.; Tews, D.; Hunter, Z.; Muench, J.; Buske, C.
10.1101/2020.10.19.344812 — cancer biology — Posted on 2020-10-19
1829 DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy
Wang, Y.; Hannon, E.; Grant, O. A.; Gorrie-Stone, T. J.; Kumari, M.; Mill, J.; Zhai, X.; McDonald-Maier, K. D.; Schalkwyk, L. C.
10.1101/2020.10.19.345090 — bioinformatics — Posted on 2020-10-19
1830 Resource reallocation in engineered Escherichia coli strains with reduced genomes
Egbert, R.; Chazin-Gray, A.; Nakayasu, E. S.; Eaton, A.; Francis, R.; Auberry, D.; Munoz, N.; Cottam, J.; Zucker, J.; Kumar, N.; Nicora, C.; Mitchell, H.; Kim, Y.-M.; Nelson, W. C.
10.1101/2020.10.19.346155 — bioengineering — Posted on 2020-10-19
1831 Vectorchip: Microfluidic platform for highly parallel bite by bite profiling of mosquito-borne pathogen transmission
Kumar, S.; Hol, F. J.; Pujhari, S.; Ellington, C.; Narayanan, H. V.; Li, H.; Rasgon, J. L.; Prakash, M.
10.1101/2020.10.19.345603 — bioengineering — Posted on 2020-10-19
1834 Diversity and genomic determinants of the microbiomes associated with COVID-19 and non-COVID respiratory diseases
Hoque, M. N.; Rahman, M. S.; Ahmed, R.; Hossain, M. S.; Islam, M. S.; Crandall, K. A.; Islam, T.; Hossain, M. A.; Siddiki, A. Z.
10.1101/2020.10.19.345702 — genomics — Posted on 2020-10-19
1839 Primed smooth muscle cells acting as first responder cells in disease
Worssam, M. D.; Lambert, J.; Oc, S.; Taylor, A. L.; Dobnikar, L.; Chappell, J.; Harman, J. L.; Figg, N. L.; Finigan, A.; Foote, K.; Uryga, A. K.; Bennett, M. R.; spivakov, M.; Jorgensen, H.
10.1101/2020.10.19.345769 — cell biology — Posted on 2020-10-19
1841 Temporal regulation of motor behavior on a modified forelimb dexterity test in mice
Mohammed, H.; Li, Y.; Di Grazia, P.; Bernstein, A.; Agger, S.; Hollis, E. R.
10.1101/2020.10.18.344507 — neuroscience — Posted on 2020-10-19
1842 Winter activity of boreal bats
Blomberg, A. S.; Vasko, V.; Meierhofer, M.; Johnson, J. S.; Eeva, T.; Lilley, T.
10.1101/2020.10.19.345124 — zoology — Posted on 2020-10-19
1843 Retrospective cell lineage reconstruction in Humans using short tandem repeats
Tao, L.; Raz, O.; Marx, Z.; Gosh, M.; Huber, S.; Greindl-Junghans, J.; Biezuner, T.; Amir, S.; Milo, L.; Adar, R.; Levy, R.; Onn, A.; Chapal-Ilani, N.; Berman, V.; Ben, A.; Rom, G.; Oron, B.; Halaban, R.; T. Czyz, Z.; Werner-Klein, M.; Klein, C. A.; Shapiro, E.
10.1101/191296 — systems biology — Posted on 2020-10-19
1845 Evolution of structural dynamics in bilobed proteins
Gouridis, G.; Muthahari, Y.; de Boer, M.; Tassis, K.; Tsirigotaki, A.; Zijlstra, N.; Eleftheriadis, N.; Xu, R.; Zacharias, M.; Griffith, D. A.; Sugijo, Y.; Doemling, A.; Karamanou, S.; Economou, A.; Cordes, T.
10.1101/2020.10.19.344861 — biophysics — Posted on 2020-10-19
1847 COVID-19: Variant screening, an important step towards precision epidemiology
Chattopadhyay, A.; Lu, T.-P.; Shih, C.-Y.; Lai, L.-C.; Tsai, M.-H.; Chuang, E. Y.
10.1101/2020.10.19.345140 — genomics — Posted on 2020-10-19
1850 Cyclase-associated protein 2 (CAP2) controls MRTF-A localization and SRF activity in mouse embryonic fibroblasts
Kepser, L.-J.; Hinojosa, L. S.; Macchi, C.; Ruscica, M.; Marcello, E.; Culmsee, C.; Grosse, R.; Rust, M. B.
10.1101/2020.10.19.344929 — cell biology — Posted on 2020-10-19
1853 Multi-omic Single-cell Atlas Reveals Broad Ex Vivo Effects on Human Immunobiology
Savage, A. K.; Gutschow, M. V.; Chiang, T.; Henderson, K.; Green, R.; Chaudhari, M.; Swanson, E.; Heubeck, A. T.; Kondza, N.; Burley, K. C.; Genge, P. C.; Lord, C.; Smith, T.; Beaubien, A.; Goldy, J.; Bolouri, H.; Buckner, J. H.; Meijer, P.; Coffey, E. M.; Li, X.-j.; Skene, P. J.; Torgerson, T. R.; Bumol, T. F.
10.1101/2020.10.18.344663 — immunology — Posted on 2020-10-19
1854 Child abuse associates with increased recruitment of perineuronal nets in the ventromedial prefrontal cortex: evidence for an implication of oligodendrocyte progenitor cells
Tanti, A.; Belliveau, C.; Nagy, C.; Maitra, M.; Denux, F.; Perlman, K.; Chen, F.; Mpai, R.; Canonne, C.; Davoli, M.-A.; Turecki, G.; Mechawar, N.
10.1101/2020.10.19.345355 — neuroscience — Posted on 2020-10-19
1855 Hierarchical imaging and computational analysis of three-dimensional vascular network architecture in the entire postnatal and adult mouse brain
Waelchli, T.; Bisschop, J.; Miettinen, A.; Ulmann-Schuler, A.; Hintermueller, C.; Meyer, E. P.; Krucker, T.; Waelchli, R.; Monnier, P.; Carmeliet, P.; Vogel, J.; Stampanoni, M.
10.1101/2020.10.19.344903 — neuroscience — Posted on 2020-10-19
1863 Quinomycin A reduces cyst progression in Polycystic Kidney Disease
Radadiya, P. S.; Thornton, M. M.; Magenheimer, B.; Subramaniam, D.; Tran, P. V.; Calvet, J. P.; Wallace, D. P.; Sharma, M.
10.1101/2020.10.18.344689 — genetics — Posted on 2020-10-19
1864 Parental CG and CHG methylation variation is associated with allelic-specific expression in elite hybrid rice
Ma, X.; Xing, F.; Jia, Q.; Zhang, Q.; Hu, T.; Wu, B.; Shao, L.; Zhao, Y.; Zhang, Q.; Zhou, D.-X.
10.1101/2020.10.19.345892 — genetics — Posted on 2020-10-19
1867 Alteration of coastal productivity and artisanal fisheries interact to affect a marine food-web
Avila-Thieme, M. I.; Corcoran, D.; Perez-Matus, A.; Wieters, E. A.; Navarrete, S. A.; Marquet, P. A.; Valdovinos, F. S.
10.1101/2020.10.18.343756 — ecology — Posted on 2020-10-19
1868 Cooperation-based sperm clusters mediate sperm oviduct entry and fertilization
Qu, Y.; Chen, Q.; Guo, S.; Ma, C.; Lu, Y.; Shi, J.; Liu, S.; Zhou, T.; Noda, T.; Qian, J.; Zhang, L.; Zhu, X.; Lei, X.; Cao, Y.; Li, W.; Li, W.; Plachta, N.; Matzuk, M. M.; Ikawa, M.; Duan, E.; Zhang, Y.; Wang, H.
10.1101/2020.10.18.344275 — developmental biology — Posted on 2020-10-19
1872 Defective Repression of OLE3::LUC 1 (DROL1) is specifically required for the splicing of AT-AC-type introns in Arabidopsis
Suzuki, T.; Shinagawa, T.; Niwa, T.; Akeda, H.; Hashimoto, S.; Tanaka, H.; Yamasaki, F.; Kawai, T.; Higashiyama, T.; Nakamura, K.
10.1101/2020.10.19.345900 — molecular biology — Posted on 2020-10-19
1873 SARS-CoV and SARS-CoV-2 are transmitted through the air between ferrets over more than one meter distance
Kutter, J. S.; de Meulder, D.; Bestebroer, T. M.; Lexmond, P.; Mulders, A.; Fouchier, R. A.; Herfst, S.
10.1101/2020.10.19.345363 — microbiology — Posted on 2020-10-19
1874 Structural basis of SARS-CoV-2 polymerase inhibition by Favipiravir
Peng, Q.; Peng, R.; Yuan, B.; Wang, M.; Zhao, J.; Fu, L.; Qi, J.; Shi, Y.
10.1101/2020.10.19.345470 — microbiology — Posted on 2020-10-19
1875 A novel viral protein translation mechanism reveals mitochondria as a target for antiviral drug development
Cheng, Z.; Zhang, D.; Chen, J.; Wu, Y.; Liu, X.; Si, L.; Zhang, Z.; Zhang, N.; Zhang, Z.; Liu, W.; Liu, H.; Zhang, L.; Song, L.; Dunmall, L. S. C.; Dong, J.; Lemoine, N. R.; Wang, Y.
10.1101/2020.10.19.344713 — microbiology — Posted on 2020-10-19
1876 Development and pre-clinical characterization of two therapeutic equine formulations towards SARS-CoV-2 proteins for the potential treatment of COVID-19
Leon, G.; Herrera, M.; Vargas, M.; Arguedas, M.; Sanchez, A.; Segura, A.; Gomez, A.; Solano, G.; Corrales-Aguilar, E.; Risner, K.; Narayanan, A.; Bailey, C.; Villalta, M.; Hernandez, A.; Sanchez, A.; Cordero, D.; Solano, D.; Duran, G.; Segura, E.; Cerdas, M.; Umana, D.; Moscoso, E.; Estrada, R.; Gutierrez, J.; Mendez, M.; Castillo, A. C.; Sanchez, L.; Gutierrez, J. M.; Diaz, C.; Alape, A.
10.1101/2020.10.17.343863 — microbiology — Posted on 2020-10-19
1877 Urine single cell RNA-sequencing in focal segmental glomerulosclerosis reveals inflammatory signatures in immune cells and podocytes
Latt, K. Z.; Heymann, J.; Jessee, J. H.; Rosenberg, A. Z.; Berthier, C. C.; Eddy, S.; Yoshida, T.; Zhao, Y.; Chen, V.; Nelson, G. W.; Cam, M.; Kumar, P.; Mehta, M.; Kelly, M. C.; Kretzler, M.; The Nephrotic Syndrome Study Network (NEPTUNE), ; The Accelerating Medicines Partnership in RA and SLE (AMP RA/SLE) consortium, ; Winkler, C. A.; Kopp, J. B.
10.1101/2020.10.18.343285 — immunology — Posted on 2020-10-19
1878 SARS-CoV-2 genome-wide mapping of CD8 T cell recognition reveals strong immunodominance and substantial CD8 T cell activation in COVID-19 patients
Saini, S. K.; Hersby, D. S.; Tamhane, T.; Povlsen, H. R.; Amaya Hernandez, S. P.; Nielsen, M.; Gang, A. O.; Hadrup, S. R.
10.1101/2020.10.19.344911 — immunology — Posted on 2020-10-19
1879 The microbiota plays a critical role in the reactivity of lung immune components to innate ligands
Marquant, Q.; Laubreton, D.; Drajac, C.; Mathieu, E.; Bouguyon, E.; Noordine, M.-L.; Remot, A.; Riffault, S.; Thomas, M.; Descamps, D.
10.1101/2020.10.19.345116 — immunology — Posted on 2020-10-19
1880 Testing The Role Of Δ9-Tetrahydrocannabinol During Adolescence As A Gateway Drug: Behavioural, Brain Imaging And Transcriptomic Studies
Orihuel, J.; Capellan, R.; Roura-Martinez, D.; Ucha, M.; Gomez-Rubio, L.; Valverde, C.; Casquero-Veiga, M.; Soto-Montenegro, M. L.; Desco, M.; Oteo-Vives, M.; Ibanez Moragues, M.; Magro-Calvo, N.; Morcillo, M. A.; Ambrosio, E.; Higuera-Matas, A.
10.1101/2020.10.19.345322 — neuroscience — Posted on 2020-10-19
1881 3D analysis of the synaptic organization in the Entorhinal cortex in Alzheimer's disease
Dominguez-Alvaro, M.; Montero-Crespo, M.; Blazquez-Llorca, L.; DeFelipe, J.; Alonso-Nanclares, L.
10.1101/2020.10.19.345025 — neuroscience — Posted on 2020-10-19
1884 High-resolution cryo-EM structure of photosystem II: Effects of electron beam damage
Kato, K.; Miyazaki, N.; Hamaguchi, T.; Nakajima, Y.; Akita, F.; Yonekura, K.; Shen, J.-R.
10.1101/2020.10.18.344648 — biophysics — Posted on 2020-10-19
1888 PIEZO1-induced cellular retraction controls keratinocyte migration in wound healing
Holt, J. R.; Zeng, W.-Z.; Evans, E. L.; Woo, S.-H.; Ma, S.; Abuwarda, H.; Loud, M.; Patapoutian, A.; Pathak, M. M.
10.1101/2020.10.18.344598 — cell biology — Posted on 2020-10-19
1889 Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interaction
Guimond, S. E.; Mycroft-West, C. J.; Gandhi, N. S.; Tree, J. A.; Buttigieg, K. R.; Coombes, N.; Elmore, M. J.; Nystrom, K.; Said, J.; Setoh, Y. X.; Amarilla, A.; Modhiran, N.; Sng, D. J. J.; Chhabra, M.; Watterson, D.; Young, P. R.; Khromykh, A. A.; Lima, M. A.; Fernig, D. G.; Su, D.; Yates, E. A.; Karlsson, R.; Chen, Y.-H.; Zhang, Y.; Hammond, E.; Dredge, K.; Carroll, M. W.; Trybala, E.; Bergstrom, T.; Ferro, V.; Skidmore, M. A.; Turnbull, J. E.
10.1101/2020.06.24.169334 — microbiology — Posted on 2020-10-19
1890 Plasmablast-derived antibody response to acute SARS-CoV-2 infection in humans
Huang, K.-Y. A.; Tan, T.; Chen, T.-H.; Huang, C.-G.; Harvey, R.; Hussain, S.; Chen, C.-P.; Harding, A.; Gilbert-Jaramillo, J.; Liu, X.; Knight, M.; Schimanski, L.; Shih, S.-R.; Lin, Y.-C.; Cheng, C.-Y.; Cheng, S.-H.; Huang, Y.-C.; Lin, T.-Y.; Rahikainen, R.; Howarth, M.; Jan, J.-T.; Ma, C.; James, W. S.; Daniels, R.; McCauley, J.; Rijal, P.; Townsend, A.
10.1101/2020.08.28.267526 — microbiology — Posted on 2020-10-19
1894 Differential effects of prediction and adaptation along the cortical hierarchy during deviance processing
Schlossmacher, I.; Dilly, J.; Protmann, I.; Hofmann, D.; Dellert, T.; Roth-Paysen, M.-L.; Moeck, R.; Bruchmann, M.; Straube, T.
10.1101/2020.10.19.339234 — neuroscience — Posted on 2020-10-19
1896 Ancient DNA reveals the lost domestication history of South American camelids in Northern Chile and across the Andes
Diaz-Maroto, P.; de la Iglesia, A. R.; Fasting, I. C.; Atencio, L. N.; Westbury, M. V.; Varas, V.; Vergara, M. M.; Campos, P. F.; Orozco-terWengel, P.; Marin, J. C.; Hansen, A. J.
10.1101/2020.10.16.337428 — evolutionary biology — Posted on 2020-10-19
1898 Gulf of Mexico blue hole harbors high levels of novel microbial lineages
Patin, N. V.; Dietrich, Z. A.; Stancil, A.; Quinan, M.; Beckler, J.; Hall, E. R.; Culter, J.; Smith, C. G.; Taillefert, M.; Stewart, F. J.
10.1101/2020.10.18.342550 — microbiology — Posted on 2020-10-19
1899 Prenatal Environmental Stressors Impair Postnatal Microglia Function and Adult Behavior in Males
Block, C. L.; Eroglu, O.; Mague, S. D.; Sriworarat, C.; Blount, C.; Malacon, K. E.; Beben, K. A.; Ndubuizu, N.; Talbot, A.; Gallagher, N.; Jo, Y. C.; Nyangacha, T.; Carlson, D.; Dzirasa, K.; Eroglu, C.; Bilbo, S. D.
10.1101/2020.10.15.336669 — neuroscience — Posted on 2020-10-19
1902 Mapping sites of carboxymethyllysine modification on proteins reveals its consequences for proteostasis and cell proliferation
Di Sanzo, S.; Spengler, K.; Leheis, A.; Kirkpatrick, J. M.; Raendler, T. L.; Baldensperger, T.; Parca, L.; Marx, C.; Wang, Z. Q.; Glomb, M. A.; Ori, A.; Heller, R.; Heller, R.
10.1101/2020.10.16.342311 — biochemistry — Posted on 2020-10-19
1904 Relative demographic susceptibility does not explain the extinction chronology of Sahul's megafauna
Bradshaw, C. J. A.; Johnson, C. N.; Llewelyn, J.; Weisbecker, V.; Strona, G.; Saltre, F.
10.1101/2020.10.16.342303 — ecology — Posted on 2020-10-19
1906 Respiratory tract explant infection dynamics of influenza A virus in California sea lions, northern elephant seals, and rhesus macaques and severe acute respiratory syndrome virus-2 in rhesus macaques
Liu, H.; Plancarte, M.; Ball, E. E.; Weiss, C. M.; Gonzales-Viera, O.; Holcomb, K.; Ma, Z.-M.; Allen, A. M.; Reader, J. R.; Duignan, P. J.; Halaska, B.; Khan, Z.; Kriti, D.; Dutta, J.; van Bakel, H.; Jackson, K.; Pesavento, P. A.; Boyce, W. M.; Coffey, L. L.
10.1101/2020.10.15.342055 — microbiology — Posted on 2020-10-19
1907 Whole Exome Sequencing identifies multiple pathogenic variants in a large south Indian family with Primary Open Angle Glaucoma
Mohd, H. S.; Kumaran, M.; Chermakani, P.; Abdul Kader, M.; R, R.; Subbiah., K. R.; Devarajan, B.; Periasamy, S.
10.1101/2020.09.21.306191 — genomics — Posted on 2020-10-19
1908 Novel polygenic risk score as a translational tool linking depression-related changes in the corticolimbic transcriptome with neural face processing and anhedonic symptoms
Mareckova, K.; Hawco, C.; Dos Santos, F. C.; Bakht, A.; Calarco, N.; Miles, A. E.; Voineskos, A. N.; Sibille, E.; Hariri, A. R.; Nikolova, Y.
10.1101/556852 — neuroscience — Posted on 2020-10-19
1909 Hierarchical motor adaptations negotiate failures during force field learning
Ikegami, T.; Ganesh, G.; Gibo, T. L.; Yoshioka, T.; Osu, R.; Kawato, M.
10.1101/2020.07.16.207084 — neuroscience — Posted on 2020-10-19
1911 High complexity cellular barcoding and clonal tracing reveals stochastic and deterministic parameters of radiation resistance
Nowrouzi, A.; Wursthorn, A.; Schwager, C.; Kurth, I.; Peitzsch, C.; Herold-Mende, C.; Debus, J.; Abdollahi, A.
10.1101/2020.10.13.337519 — systems biology — Posted on 2020-10-19
1913 Susceptible host availability modulates climate effects on dengue dynamics
Nova, N.; Deyle, E. R.; Shocket, M. S.; MacDonald, A. J.; Childs, M.; Rypdal, M.; Sugihara, G.; Mordecai, E. A.
10.1101/2019.12.20.883363 — ecology — Posted on 2020-10-19
1914 Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19
Tindle, C.; Fuller, M.; Fonseca, A.; Taheri, S.; Ibeawuchi, S.-R.; Beutler, N.; Claire, A.; Castillo, V.; Hernandez, M.; Russo, H.; Duran, J.; Crotty Alexander, L. E.; Tipps, A.; Lin, G.; Thistlethwaite, P. A.; Chattopadhyay, R.; Rogers, T. F.; Sahoo, D.; Ghosh, P.; Das, S.
10.1101/2020.10.17.344002 — cell biology — Posted on 2020-10-19
1915 Role of Mcpip1 in obesity-induced hepatic steatosis as determined by myeloid and liver-specific conditional knockouts.
Pydyn, N.; Zurawek, D.; Koziel, J.; Kus, E.; Wojnar-Lason, K.; Jasztal, A.; Fu, M.; Jura, J.; Kotlinowski, J.
10.1101/2020.09.17.301531 — molecular biology — Posted on 2020-10-19
1916 DeepACSON: Automated Segmentation of White Matter in 3D Electron Microscopy
Abdollahzadeh, A.; Belevich, I.; Jokitalo, E.; Sierra, A.; Tohka, J.
10.1101/828541 — neuroscience — Posted on 2020-10-19
1917 A White Matter Atlas and Common Connectivity Space Facilitate the Pig as a Translational Model in Neuroscience
Benn, R. A.; Mars, R. B.; Xu, T.; Rodriguez-Esparragoza, L.; Montesinos, P.; Manzano-Patron, J. P.; Lopez-Martin, G.; Fuster, V.; Gonzalez-Sanchez, J.; Duff, E. P.; Ibanez, B.
10.1101/2020.10.13.337436 — neuroscience — Posted on 2020-10-19
1919 HippoUnit: A software tool for the automated testing and systematic comparison of detailed models of hippocampal neurons based on electrophysiological data
Saray, S.; Rössert, C. A.; Appukuttan, S.; Migliore, R.; Vitale, P.; Lupascu, C. A.; Bologna, L. L.; Van Geit, W.; Romani, A.; Davison, A. P.; Muller, E.; Freund, T. F.; Kali, S.
10.1101/2020.07.02.184333 — neuroscience — Posted on 2020-10-19
1922 Construction of a third NAD+ de novo biosynthesis pathway
Ding, Y.; Li, X.; Horsman, G. P.; Li, P.; Wang, M.; Li, J.; Zhang, Z.; Liu, W.; Wu, B.; Tao, Y.; Chen, Y.
10.1101/2020.10.18.342451 — synthetic biology — Posted on 2020-10-18
1926 Transovarial transmission fuels persistent infections of a core virome in the Chagas disease vector Rhodnius prolixus
Brito, T. F. d.; Coelho, V. L.; Cardoso, M. A.; Brito, I. A. d. A.; Zenk, F. L.; Iovino, N.; Pane, A.
10.1101/2020.10.18.344325 — immunology — Posted on 2020-10-18
1927 Citrulline supplementation improves spatial memory in a murine model for Alzheimer's disease
Martinez-Gonzalez, K.; Serrano-Cuevas, L.; Almeida-Gutierrez, E.; Flores-Chavez, S.; Mejia-Arangure, J. M.; Garcia-delaTorre, P.
10.1101/2020.06.15.153346 — neuroscience — Posted on 2020-10-18
1928 Fundamental limits on the rate of bacterial growth
Belliveau, N. M.; Chure, G. D.; Hueschen, C. L.; Garcia, H. G.; Kondev, J.; Fisher, D. S.; Theriot, J. A.; Phillips, R.
10.1101/2020.10.18.344382 — systems biology — Posted on 2020-10-18
1929 Programmable Aggregation of Artificial Cells with DNA Signals
Qiu, H.; Li, F.; Du, Y.; Li, R.; Hyun, J. Y.; Lee, S. Y.; Choi, J. H.
10.1101/2020.10.18.344432 — synthetic biology — Posted on 2020-10-18
1930 RNA-Seq Time Series of Vitis vinifera Bud Development Reveals Correlation of Expression Patterns with the Local Temperature Profile
Pucker, B.; Schwandner, A.; Becker, S.; Hausmann, L.; Viehöver, P.; Töpfer, R.; Weisshaar, B.; Holtgräwe, D.
10.1101/2020.10.18.344176 — plant biology — Posted on 2020-10-18
1932 Cardiovascular Disease Related Proteomic Biomarkers of Alcohol Consumption
Sun, X.; Ho, J.; Gao, H.; Evangelou, E.; Yao, C.; Huan, T.; Hwang, S.-J.; Courchesne, P.; Larson, M.; Levy, D.; Ma, J.; Liu, C.
10.1101/2020.10.17.332197 — bioinformatics — Posted on 2020-10-18
1937 Feeding habits and novel prey of larval fishes in the northern San Francisco Estuary
Jungbluth, M. J.; Burns, J.; Grimaldo, L.; Slaughter, A.; Katla, A.; Kimmerer, W.
10.1101/2020.10.18.344440 — ecology — Posted on 2020-10-18
1939 Derivation of human extended pluripotent stem cells in feeder-free condition
Zheng, R.; Geng, T.; Wu, D.-Y.; Zhang, T.; He, H.-N.; Wang, L.; Du, H.; Zhang, D.; Miao, Y.-L.; Jiang, W.
10.1101/2020.10.18.344259 — developmental biology — Posted on 2020-10-18
1942 Autotoxin-mediated voluntary triage in starved yeast community
Oda, A. H.; Tamura, M.; Kaneko, K.; Ohta, K.; Hatakeyama, T. S.
10.1101/2020.10.17.344093 — microbiology — Posted on 2020-10-18
1943 Place cells in head-fixed mice navigating a floating real-world environment
Go, M. A.; Rogers, J.; Gava, G. P.; Davey, C.; Prado, S.; Liu, Y.; Schultz, S. R.
10.1101/2020.10.18.344184 — neuroscience — Posted on 2020-10-18
1946 Understanding how an amphicarpic species with a mixed mating system responds to fire: a population genetic approach
Meyer, E. M.; Swift, J. F.; Bassuner, B.; Smith, S. A.; Menges, E. S.; Oberle, B.; Edwards, C. E.
10.1101/2020.10.18.344036 — plant biology — Posted on 2020-10-18
1952 The Genomic History of the Middle East
Almarri, M. A.; Haber, M.; Lootah, R. A.; Hallast, P.; Al Turki, S.; Martin, H. C.; Xue, Y.; Tyler-Smith, C.
10.1101/2020.10.18.342816 — genomics — Posted on 2020-10-18
1953 Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19
Tindle, C.; Fuller, M.; Fonseca, A.; Taheri, S.; Ibeawuchi, S.-R.; Beutler, N.; Claire, A.; Castillo, V.; Hernandez, M.; Russo, H.; Duran, J.; Crotty Alexander, L. E.; Tipps, A.; Lin, G.; Thistlethwaite, P. A.; Chattopadhyay, R.; Rogers, T. F.; Sahoo, D.; Ghosh, P.; Das, S.
10.1101/2020.10.17.344002 — cell biology — Posted on 2020-10-18
1954 3D reconstruction of SARS-CoV-2 infection in ferrets emphasizes focal infection pattern in the upper respiratory tract
Zaeck, L. M.; Scheibner, D.; Sehl, J.; Müller, M.; Hoffmann, D.; Beer, M.; Abdelwhab, E. M.; Mettenleiter, T. C.; Breithaupt, A.; Finke, S.
10.1101/2020.10.17.339051 — microbiology — Posted on 2020-10-18
1955 Spatial preferences account for inter-animal variability during the continual learning of a dynamic cognitive task
Kastner, D. B.; Miller, E. A.; Yang, Z.; Roumis, D. K.; Liu, D. F.; Frank, L. M.; Dayan, P.
10.1101/808006 — neuroscience — Posted on 2020-10-18
1956 The Design Principles of Discrete Turing Patterning Systems
Leyshon, T.; Tonello, E.; Schnoerr, D. B.; Siebert, H.; Stumpf, M. P. H.
10.1101/2020.10.18.344135 — systems biology — Posted on 2020-10-18
1957 The dynamic, combinatorial cis-regulatory lexicon of epidermal differentiation
Kim, D. S.; Risca, V.; Reynolds, D.; Chappell, J.; Rubin, A.; Jung, N.; Donohue, L.; Kathiria, A.; Shi, M.; Zhao, Z.; Deep, H.; Chang, H. Y.; Snyder, M. P.; Greenleaf, W. J.; Kundaje, A.; Khavari, P. A.
10.1101/2020.10.16.342857 — genomics — Posted on 2020-10-18
1958 Hmx3a has essential functions in zebrafish spinal cord, ear and lateral line development.
England, S. J.; Cerda, G. A.; Kowalchuk, A. M.; Sorice, T.; Grieb, G. M.; Lewis, K. E.
10.1101/2020.01.23.917468 — genetics — Posted on 2020-10-18
1967 Quantifying and modelling the acquisition and retention of lumpy skin disease virus by haematophagus insects reveals clinically but not subclinically-affected cattle are promoters of viral transmission and key targets for control of disease outbreaks.
Sanz-Bernardo, B.; Haga, I. R.; Wijesiriwardana, N.; Basu, S.; Larner, W.; Diaz, A. V.; Langlands, Z.; Denison, E.; Stoner, J.; White, M.; Sanders, C.; Hawes, P. C.; Wilson, A. J.; Atkinson, J.; Batten, C.; Alphey, L.; Darpel, K. E.; Gubbins, S.; Beard, P. M.
10.1101/2020.06.18.154252 — microbiology — Posted on 2020-10-18
1971 cis dominantly explains regulatory divergence between two indica rice genotypes; drought further enhances regulatory differences
Ereful, N. C.; Laurena, A.; Liu, L.-y.; Kao, S.-M.; Tsai, E.; Thomson, M.; Greenland, A.; Powell, W.; Mackay, I.; Leung, H.
10.1101/714907 — plant biology — Posted on 2020-10-18
1972 Identification of novel avian and mammalian deltaviruses provides new insights into deltavirus evolution
Iwamoto, M.; Shibata, Y.; Kawasaki, J.; Kojima, S.; Li, Y.-T.; Iwami, S.; Wu, H.-L.; Wada, K.; Tomonaga, K.; Watashi, K.; Horie, M.
10.1101/2020.08.30.274571 — microbiology — Posted on 2020-10-18
1974 Unlocking Elementary Conversion Modes: ecmtool unveils all capabilities of metabolic networks
Clement, T. J.; Baalhuis, E. B.; Teusink, B.; Bruggeman, F. J.; Planque, R.; de Groot, D. H.
10.1101/2020.06.06.137554 — systems biology — Posted on 2020-10-17
1975 Salmonella Typhi acquires diverse plasmids from other Enterobacteriaceae to develop cephalosporin resistance
Jacob, J. J.; Pragasam, A. K.; Vasudevan, K.; Veeraraghavan, B.; Kang, G.; John, J.; Nagvekar, V.; Mutreja, A.
10.1101/2020.10.16.343467 — genomics — Posted on 2020-10-17
1982 Cardiovascular Disease Related Proteomic Biomarkers of Alcohol Consumption
Sun, X.; Ho, J.; Gao, H.; Evangelou, E.; Yao, C.; Huan, T.; Hwang, S.-J.; Courchesne, P.; Larson, M.; Levy, D.; Ma, J.; Liu, C.
10.1101/2020.10.17.332197 — bioinformatics — Posted on 2020-10-17
1984 Chromatin conformation capture (Hi-C) sequencing of patient-derived xenografts: analysis guidelines
Dozmorov, M. G.; Tyc, K. M.; Sheffield, N. C.; Boyd, D. C.; Olex, A. L.; Reed, J.; Harrell, J. C.
10.1101/2020.10.17.343814 — genomics — Posted on 2020-10-17
1986 AniProtDB: A Collection of Uniformly Generated Metazoan Proteomes for Comparative Genomics Studies
Barreira, S. N.; Nguyen, A.-D.; Fredriksen, M. T.; Wolfsberg, T. G.; Moreland, R. T.; Baxevanis, A. D.
10.1101/2020.10.17.342964 — genomics — Posted on 2020-10-17
1987 The dynamic, combinatorial cis-regulatory lexicon of epidermal differentiation
Kim, D. S.; Risca, V.; Reynolds, D.; Chappell, J.; Rubin, A.; Jung, N.; Donohue, L.; Kathiria, A.; Shi, M.; Zhao, Z.; Deep, H.; Chang, H. Y.; Snyder, M. P.; Greenleaf, W. J.; Kundaje, A.; Khavari, P. A.
10.1101/2020.10.16.342857 — genomics — Posted on 2020-10-17
1988 Relative time constraints improve molecular dating
Szollosi, G. J.; Hoehna, S.; Williams, T. A.; Schrempf, D.; Daubin, V.; Boussau, B.
10.1101/2020.10.17.343889 — evolutionary biology — Posted on 2020-10-17
1989 Mitochondrial fission governed by Drp1 regulates exogenous fatty acid usage and storage
Song, J. E.; Alves, T.; Stutz, B.; Sestan-Pesa, M.; Kilian, N.; Diano, S.; Kibbey, R.; Horvath, T.
10.1101/2020.10.17.343616 — cell biology — Posted on 2020-10-17
1990 Strain population structure varies widely across bacterial species and predicts strain colonization in unrelated individuals
Faith, J. J.; Chen Liaw, A.; Aggarwala, V.; Kaakoush, N. O.; Borody, T.; Mitchell, H.; Kamm, M. A.; Paramsothy, S.; Snitkin, E. S.; Mogno, I.
10.1101/2020.10.17.343640 — microbiology — Posted on 2020-10-17
1991 Global distribution patterns of marine nitrogen-fixers by imaging and molecular methods
Pierella Karlusich, J. J.; Pelletier, E.; Carsique, M.; Dvorak, E.; Colin, S.; Picheral, M.; Pepperkok, R.; Karsenti, E.; de Vargas, C.; Lombard, F.; Wincker, P.; Bowler, C.; Foster, R. A.
10.1101/2020.10.17.343731 — microbiology — Posted on 2020-10-17
1996 Stromal cells regulate malignant B-cell spatial organization, survival, and drug response in a new 3D model mimicking lymphoma tumor niche
Lamaison, C.; Latour, S.; Helaine, N.; Le Morvan, V.; Monvoisin, C.; Mahouche, I.; Dussert, C.; Dessauge, E.; Pangault, C.; Seffals, M.; Broca-Brisson, L.; Alessandri, K.; Soubeyran, P.; Mourcin, F.; Nassoy, P.; Recher, G.; Tarte, K.; Bresson-Bepoldin, L.
10.1101/2020.10.17.343657 — cancer biology — Posted on 2020-10-17
2000 Safe linkage of cohort and population-based register data in a genome-wide association study on health care expenditure
de Zeeuw, E. L.; Voort, L.; Schoonhoven, R.; Nivard, M. G.; Emery, T.; Hottenga, J.-J.; Willemsen, G.; Dykstra, P. A.; Zarrabi, N.; Kartopawiro, J. D.; Boomsma, D. I.
10.1101/2020.10.17.334896 — genetics — Posted on 2020-10-17
2001 Meta-GWAS for quantitative trait loci identification in soybean
Shook, J. M.; Zhang, J.; Jones, S. E.; Singh, A.; Diers, B. W.; Singh, A. K.
10.1101/2020.10.17.343707 — genetics — Posted on 2020-10-17
2002 NetworkExtinction: an R package to explore the propagation of extinctions through complex ecological networks
Avila-Thieme, M. I.; Corcoran, D.; Castillo, S. P.; Valdovinos, F. S.; Navarrete, S. A.; Marquet, P. A.
10.1101/2020.10.17.305391 — ecology — Posted on 2020-10-17
2003 Metapopulation Connectivity in Voles (Microtus sp.) as a Gauge for Tallgrass Prairie Restoration in Midwestern North America
Douglas, M. R.; Anthonysamy, W. J. B.; Davis, M. A.; Mulligan, M. P.; Schooley, R. L.; Louis, W.; Douglas, M. E.
10.1101/2020.10.17.343301 — ecology — Posted on 2020-10-17
2005 Subcellular relocalization and nuclear redistribution of the RNA methyltransferases TRMT1 and TRMT1L upon neuronal activation
Jonkhout, N.; Cruciani, S.; Vieira, H. G. S.; Tran, J.; Liu, H.; Liu, G.; Pickford, R.; Kaczorowski, D.; Franco, G. R.; Vauti, F.; Camacho, N.; Abedini, S. S.; Najmabadi, H.; Ribas de Pouplana, L.; Christ, D.; Schonrock, N.; Mattick, J. S.; Novoa, E. M.
10.1101/2020.10.17.343772 — molecular biology — Posted on 2020-10-17
2006 CD4 and CD8 co-receptors modulate functional avidity of CD1b-restricted T cells.
James, C. A.; Xu, Y.; Aguilar, M. S.; Jing, L.; Layton, E. D.; Gilleron, M.; Minnaard, A. J.; Scriba, T.; Day, C. L.; Warren, E. H.; Koelle, D. M.; Seshadri, C.
10.1101/2020.10.17.332072 — immunology — Posted on 2020-10-17
2011 Phosphate dysregulation via the XPR1:KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer
Bondeson, D. P.; Paolella, B. R.; Asfaw, A.; Rothberg, M.; Skipper, T.; Langan, C.; Gonzalez, A.; Surface, L.; Ito, K.; Kazachkova, M.; Colgan, W. N.; Warren, A.; Dempster, J.; Krill-Burger, J. M.; Ericcson, M.; Tang, A.; Fung, I.; Chambers, E. S.; Abdusamad, M.; Dumont, N.; Doench, J. G.; Piccioni, F.; Root, D. E.; Boehm, J. S.; Hahn, W. C.; Mannstadt, M.; McFarland, J. M.; Vazquez, F.; Golub, T. R.
10.1101/2020.10.16.339374 — cancer biology — Posted on 2020-10-17
2016 Therapy-induced senescence in normal tissue promotes breast cancer metastasis
Perkins, D. W.; Haider, S.; Roberston, D.; Buus, R.; O'Leary, L.; Isacke, C. M.
10.1101/2020.10.17.343590 — cancer biology — Posted on 2020-10-17
2017 Dissecting Mammalian Spermatogenesis Using Spatial Transcriptomics
Chen, H.; Murray, E.; Laumas, A.; Li, J.; Nie, X.; Hotaling, J.; Guo, J.; Cairns, B. R.; Macosko, E. Z.; Cheng, C. Y.; Chen, F.
10.1101/2020.10.17.343335 — genomics — Posted on 2020-10-17
2018 GenOrigin: A Comprehensive Protein-coding Gene Origination Database on the Evolutionary Timescale of Life
Tong, Y.-B.; Shi, M.-W.; Qian, S. H.; Chen, Y.-J.; Luo, Z.-H.; Tu, Y.-X.; Chen, C.; Chen, Z.-X.
10.1101/2020.10.17.342022 — evolutionary biology — Posted on 2020-10-17
2019 Functional spreading of hyperexcitability induced by human and synthetic intracellular Aβ oligomers
Fernandez-Perez, E. J.; Munoz, B.; Bascunan, D. A.; Peters, C.; Riffo-Lepe, N. O.; Espinoza, M. P.; Morgan, P. J.; Filippi, C.; Bourboulou, R.; Sengupta, U.; Kayed, R.; Epsztein, J.; Aguayo, L. G.
10.1101/2020.10.16.332445 — neuroscience — Posted on 2020-10-17
2021 Brain preparedness: The proactive role of the cortisol awakening response
Xiong, B.; Chen, C.; Tian, Y.; Zhang, S.; Liu, C.; Evans, T.; Fernandez, G.; Wu, J.; Qin, S.
10.1101/2020.10.17.343442 — neuroscience — Posted on 2020-10-17
2022 Variability in the diet diversity of catfish highlighted through DNA barcoding
PrasannaKumar, C.; Iyyapparajanarasimapallavan, G.; Ashiq Ur Rahman, M.; Mohanchander, P.; Sudhakar, T.; Kadharsha, K.; Feroz Khan, K.; Vijaylaxmi, J.; Prasanthi, N.; Subramanian, K.; Manokaran, S.
10.1101/2020.09.18.268888 — zoology — Posted on 2020-10-17
2027 Loss of MGA mediated Polycomb repression promotes tumor progression and invasiveness
Mathsyaraja, H.; Catchpole, J.; Eastwood, E.; Babaeva, E.; Geuenich, M. J.; Cheng, P.-F.; Freie, B.; Ayers, J. L.; Yu, M.; Wu, N.; Poudel, K. R.; Koehne, A.; Grady, W.; Houghton, A. M.; Shiio, Y.; MacPherson, D. P.; Eisenman, R. N.
10.1101/2020.10.16.334714 — cancer biology — Posted on 2020-10-17
2029 SKiM - A generalized literature-based discovery system for uncovering novel biomedical knowledge from PubMed
Raja, K.; Steill, J.; Ross, I.; Tsoi, L. C.; Kuusisto, F.; Ni, Z.; Livny, M.; Thomson, J.; Stewart, R.
10.1101/2020.10.16.343012 — bioinformatics — Posted on 2020-10-17
2030 Photochemical probe identification of the small-molecule binding site in a mammalian membrane-bound O-acyltransferase
Lanyon-Hogg, T.; Ritzefeld, M.; Zhang, L.; Pogranyi, B.; Mondal, M.; Johnston, C. D.; Coupland, C. E.; Sefer, L.; Andrei, S. A.; Newington, J.; Magee, A. I.; Siebold, C.; Tate, E. W.
10.1101/2020.10.16.342477 — biochemistry — Posted on 2020-10-17
2031 Replicability of spatial gene expression atlas data from the adult mouse brain
Lu, S.; Ortiz, C.; Furth, D.; Fischer, S.; Meletis, K.; Zador, A.; Gillis, J.
10.1101/2020.10.16.343210 — genomics — Posted on 2020-10-17
2032 Translation-dependent and independent mRNA decay occur through mutually exclusive pathways that are defined by ribosome density during T Cell activation.
Mercier, B. C.; Labaronne, E.; Cluet, D.; Bicknell, A.; Corbin, A.; Guiguettaz, L.; Aube, F.; Modolo, L.; Auboeuf, D.; Moore, M. J.; Ricci, E. P.
10.1101/2020.10.16.341222 — genomics — Posted on 2020-10-17
2035 The predator activity landscape predicts the anti-predator behavior and distribution of prey in a tundra community
Clermont, J.; Grenier-Potvin, A.; Duchesne, E.; Couchoux, C.; Dulude-de Broin, F.; Beardsell, A.; Bety, J.; Berteaux, D.
10.1101/2020.10.16.342725 — ecology — Posted on 2020-10-17
2036 Diverse viral proteases activate the NLRP1 inflammasome
Tsu, B. V.; Beierschmitt, C.; Ryan, A. P.; Agarwal, R.; Mitchell, P. S.; Daugherty, M. D.
10.1101/2020.10.16.343426 — microbiology — Posted on 2020-10-17
2037 EfgA is a conserved formaldehyde sensor that halts bacterial translation in response to elevated formaldehyde
Bazurto, J.; Nayak, D. D.; Ticak, T.; Davlieva, M.; Lee, J. A.; Lambert, L. B.; Benski, O. J.; Quates, C. J.; Johnson, J. L.; Patel, J. S.; Ytreberg, F. M.; Shamoo, Y.; Marx, C. J.
10.1101/2020.10.16.343392 — microbiology — Posted on 2020-10-17
2039 Multiple nerve rings coordinate Hydra mechanosensory behavior
Badhiwala, K. N.; Primack, A. S.; Juliano, C.; Robinson, J. T.
10.1101/2020.10.16.343384 — neuroscience — Posted on 2020-10-17
2040 Malleability of the cortical hand map following a finger nerve block
Wesselink, D. B.; Sanders, Z.-B.; Edmondson, L. R.; Dempsey-Jones, H.; Kieliba, P.; Kikkert, S.; Themistocleous, A. C.; Emir, U.; Diedrichsen, J.; Saal, H. P.; Makin, T. R.
10.1101/2020.10.16.338640 — neuroscience — Posted on 2020-10-17
2041 Distinct roles of dorsal and ventral subthalamic neurons in action selection and cancellation
Mosher, C. P.; Mamelak, A. N.; Malekmohammadi, M.; Pouratian, N.; Rutishauser, U.
10.1101/2020.10.16.342980 — neuroscience — Posted on 2020-10-17
2042 Phosphorylation-dependent sub-functionalization of the calcium-dependent protein kinase CPK28
Bredow, M.; Bender, K. W.; Johnson Dingee, A.; Holmes, D. R.; Thomson, A.; Ciren, D.; Tanney, C. A.; Dunning, K. E.; Trujillo, M.; Huber, S. C.; Monaghan, J.
10.1101/2020.10.16.338442 — plant biology — Posted on 2020-10-17
2043 Diverse Changes in Microglia Morphology and Axonal Pathology Over One Year after Mild Traumatic Brain Injury in Pigs
Grovola, M. R.; Paleologos, N.; Brown, D. P.; Tran, N.; Wofford, K.; Harris, J.; Browne, K.; Wolf, J.; Cullen, D. K.; Duda, J. E.
10.1101/2020.10.16.343103 — pathology — Posted on 2020-10-17
2044 Vasa vasorum lumen narrowing in brain vascular hyalinosis in systemic hypertension patients with ischemic stroke
Gychka, S. G.; Shults, N. V.; Nikolaienko, S. I.; Marcocci, L.; Sariipek, N. E.; Rybka, V.; Malysheva, T. A.; Dibrova, V. A.; Suzuki, Y. J.; Gavrish, A. S.
10.1101/2020.10.16.342741 — pathology — Posted on 2020-10-17
2048 Evolutionary and phylogenetic insights from a nuclear genome sequence of the extinct, giant subfossil koala lemur Megaladapis edwardsi
Marciniak, S.; Mughal, M. R.; Godfrey, L. R.; Bankoff, R. J.; Randrianatoandro, H.; Crowley, B. E.; Bergey, C. M.; Muldoon, K. M.; Randrianasy, J.; Raharivololona, B. M.; Schuster, S. C.; Malhi, R. S.; Yoder, A. D.; Louis, E. E.; Kistler, L.; Perry, G. H.
10.1101/2020.10.16.342907 — genomics — Posted on 2020-10-17
2050 Knockout of zebrafish desmin genes does not cause skeletal muscle degeneration but alters calcium flux
Kayman Kurekci, G.; Kural Mangit, E.; Koyunlar, C.; Unsal, S.; Saglam, B.; Ergin, B.; Uyanik, I.; Duz, N.; Talim, B.; Purali, N.; Hughes, S. M.; Dincer, P. R.
10.1101/2020.10.16.342485 — developmental biology — Posted on 2020-10-17
2051 Proximity Biotin Labeling Reveals KSHV Interferon Regulatory Factor Networks
Kumar, A.; Salemi, M. R.; Bhullar, R.; Guevara-Plunkett, S.; Lyu, Y.; Wang, K.-H.; Izumiya, C.; Campbell, M.; Nakajima, K.-i.; Izumiya, Y.
10.1101/2020.10.16.343483 — microbiology — Posted on 2020-10-17
2052 The JAK2-STAT pathway epigenetically regulates tolerized genes during the first encounter with bacterial antigens
Lorente-Sorolla, C.; Morante-Palacios, O.; Garcia-Gomez, A.; Ciudad, L.; Catala-Moll, F.; Ruiz-Sanmartin, A.; Martinez-Gallo, M.; Ferrer-Roca, R.; Ruiz-Rodriguez, J. C.; Alvarez-Errico, D.; Ballestar, E.
10.1101/2020.10.16.342717 — immunology — Posted on 2020-10-17
2053 Remote testing of vitamin D levels across the UK MS population - a case control study
Vickaryous, N.; Jitlal, M.; Jacobs, B. M.; Middleton, R.; Chandran, S.; MacDougall, N. J. J.; Giovannoni, G.; Dobson, R.
10.1101/2020.10.16.342253 — neuroscience — Posted on 2020-10-16
2055 Molecular and genetic approaches for assaying human cell type synaptic connectivity
Kim, M.-H.; Radaelli, C.; Thomsen, E. R.; Mahoney, J. T.; Long, B.; Taormina, M. J.; Kebede, S.; Gamlin, C.; Sorensen, S. A.; Campagnola, L.; Dee, N.; D'Orazi, F. D.; Ko, A. L.; Ojemann, J. G.; Silbergeld, D. L.; Gwinn, R. P.; Cobbs, C.; Keene, C. D.; Jarsky, T.; Murphy, G.; Zeng, H.; Nicovich, P.; Ting, J. T.; Levi, B. P.; Lein, E.
10.1101/2020.10.16.343343 — neuroscience — Posted on 2020-10-17
2059 The molecular and metabolic program for adaptation of white adipocytesto cool physiologic temperatures
MacDougald, O. A.; Mori, H.; Dugan, C.; Nishii, A.; Benchamana, A.; Li, Z.; Cadenhead, T.; Das, A.; Evans, C.; Overmyer, K.; Romanelli, S.; Peterson, S.; Bagchi, D.; Corsa, C.; Hardij, J.; Learman, B.; El Azzouny, M.; Inoki, K.
10.1101/2020.10.16.342220 — physiology — Posted on 2020-10-16
2060 Deletion of an intronic polypyrimidine tract of porcine DNAH17 perturbs splicing and causes defective sperm flagella
Noskova, A.; Hiltpold, M.; Janett, F.; Echtermann, T.; Fang, Z.-H.; Sidler, X.; Selige, C.; Hofer, A.; Neuenschwander, S.; Pausch, H.
10.1101/2020.10.16.333344 — genomics — Posted on 2020-10-16
2061 Multivariate genomic analysis of 1.5 million people identifies genes related to addiction, antisocial behavior, and health
Karlsson Linner, R.; Mallard, T. T.; Barr, P. B.; Sanchez-Roige, S.; Madole, J. W.; Driver, M. N.; Poore, H. E.; Grotzinger, A. D.; Tielbeek, J. J.; Johnson, E. C.; Liu, M.; Zhou, H.; Kember, R.; Pasman, J. A.; Verweij, K. J. H.; Liu, D.; Vrieze, S.; Kranzler, H.; Gelernter, J.; Mullan Harris, K.; Tucker-Drob, E. M.; Waldman, I. D.; Palmer, A. A.; Harden, K. P.; Koellinger, P. D.; Dick, D. M.
10.1101/2020.10.16.342501 — genetics — Posted on 2020-10-16
2063 Mitochondrial profiling reveals dynamic, sex- and age-specific mitochondrial phenotypes in human immune cell subtypes
Rausser, S.; Trumpff, C.; McGill, M. A.; Junker, A.; Wang, W.; Ho, S.-H.; Mitchell, A.; Karan, K. R.; Monk, C.; Segerstrom, S. C.; Reed, R. G.; Picard, M.
10.1101/2020.10.16.342923 — cell biology — Posted on 2020-10-16
2064 Serotype has a significant impact on the virulence of 7th pandemic Vibrio cholerae O1
Nordqvist, S. L.; Thorell, K.; Nilsson, F.; Löfstrand, M.; Hagelberg, A.; Holmgren, J.; Lebens, M.
10.1101/2020.10.16.342279 — microbiology — Posted on 2020-10-16
2067 The effect of functionally-guided-connectivity-based rTMS on amygdala activation.
Beynel, L.; Campbell, E.; Naclerio, M.; Galla, J. T.; Ghosal, A.; Michael, A. M.; Kimbrel, N. A.; Davis, S. W.; Appelbaum, L. G.
10.1101/2020.10.13.338483 — neuroscience — Posted on 2020-10-16
2072 A wild Cucurbita genome reveals the role of structural variants and introgression in domestication
Barrera-Redondo, J.; Sanchez-de la Vega, G.; Aguirre-Liguori, J. A.; Castellanos-Morales, G.; Gutierrez-Guerrero, Y. T.; Aguirre-Dugua, X.; Aguirre-Planter, E.; Tenaillon, M. I.; Lira-Saade, R.; Eguiarte, L. E.
10.1101/2020.10.15.341990 — evolutionary biology — Posted on 2020-10-16
2074 The Himalayan Uplift and the Evolution of Aquatic Biodiversity Across Asia: Snowtrout (Cyprininae: Schizothorax) as a Test Case
Regmi, B.; Douglas, M. R.; Edds, D. R.; Wangchuk, K.; Lu, C.; Khanal, G. P.; Norbu, P.; Norbu, S.; Dorji, S.; Tshering, S.; Angel, Z.; Chafin, T. K.; Zbinden, Z. D.; Douglas, M. E.
10.1101/2020.10.12.336149 — evolutionary biology — Posted on 2020-10-16
2075 AIBP-CAV1-VEGFR3 axis dictates lymphatic cell fateand controls lymphangiogenesis
Yang, X.; Kim, J.; Gu, Q.; Yan, Q.; Astin, J.; Crosier, P.; Yu, P.; Rockson, S. G.; Fang, L.
10.1101/2020.10.16.342998 — developmental biology — Posted on 2020-10-16
2076 Cytoplasmic innate immune sensing by the caspase-4 non-canonical inflammasome promotes cellular senescence.
Fernandez Duran, I.; Tarrats, N.; Birch, J.; Hari, P.; Millar, F. R.; Muir, M.; Quintanilla, A.; Brunton, V. G.; Passos, J. F.; Acosta, J. C.
10.1101/2020.10.16.342949 — cell biology — Posted on 2020-10-16
2080 Differential thermotolerance adaptation between species of Coccidioides
Mead, H. L.; Hamm, P. S.; Shaffer, I. N.; de Melo Teixeira, M.; Wendel, C.; Wiederhold, N. P.; Thompson, G. R.; Muniz-Salazar, R.; Castanon-Olivares, L. R.; Keim, P.; Plude, C.; Terriquez, J.; Galgiani, J. N.; Orbach, M. J.; Barker, B. M.
10.1101/2020.08.12.247635 — microbiology — Posted on 2020-10-16
2085 Large-scale transcriptomics to dissect two years of the life of a fungal phytopathogen interacting with its host plant
Gay, E. J.; Soyer, J. L.; Lapalu, N.; Linglin, J.; Fudal, I.; Da Silva, C.; Wincker, P.; Aury, J.-M.; Cruaud, C.; Levrel, A.; Lemoine, J.; Delourme, R.; Rouxel, T.; Balesdent, M.-H.
10.1101/2020.10.13.331520 — pathology — Posted on 2020-10-16
2087 Confinement Discerns Swarmers from Planktonic Bacteria
Chen, W.; Mani, N.; Karani, H.; Li, H.; Mani, S.; Tang, J. X.
10.1101/2020.08.30.274316 — biophysics — Posted on 2020-10-16
2094 Simplified artificial blood feeding and oral infection method for mosquitoes
Pereira, T. N.; Carvalho, F. D.; Silva, L. H.; Mendonca, S. F.; Moreira, L. A.
10.1101/2020.10.16.342584 — developmental biology — Posted on 2020-10-16
2097 The discovery, distribution and diversity of DNA viruses associated with Drosophila melanogaster in Europe
Wallace, M. A.; Coffman, K. A.; Gilbert, C.; Ravindran, S.; Albery, G. F.; Abbott, J.; Argyridou, E.; Bellosta, P.; Betancourt, A. J.; Colinet, H.; Eric, K.; Glaser-Schmitt, A.; Grath, S.; Jelic, M.; Kankare, M.; Kozeretska, I.; Loeschcke, V.; Montchamp-Moreau, C.; Ometto, L.; Onder, B. S.; Orengo, D. J.; Parsch, J.; Pascual, M.; Patenkovic, A.; Puerma, E.; Ritchie, M. G.; Rota-Stabelli, O.; Schou, M. F.; Serga, S. V.; Stamenkovic-Radak, M.; Tanaskovic, M.; Veselinovic, M. S.; Vieira, J.; Vieira, C. P.; Kapun, M.; Flatt, T.; Gonzalez, J.; Staubach, F.; Obbard, D. J.
10.1101/2020.10.16.342956 — microbiology — Posted on 2020-10-16
2099 Physical activity and general cognitive functioning: A Mendelian Randomization study
Cheval, B.; Darrous, L.; Choi, K.; Klimentidis, Y.; Raichlen, D.; Alexander, G.; Cullati, S.; Kutalik, Z.; Boisgontier, M. P.
10.1101/2020.10.16.342675 — neuroscience — Posted on 2020-10-16
2100 Expression of FoxP2 in the Basal Ganglia Regulates Vocal Motor Sequences in the Adult Songbird
Xiao, L.; Merullo, D. P.; Cao, M.; Co, M.; Kulkarni, A.; Konopka, G.; Roberts, T. F.
10.1101/2020.03.14.991042 — neuroscience — Posted on 2020-10-16
2102 Chemical Systems Biology Reveals Mechanisms of Glucocorticoid Receptor Signaling
Bruno, N.; Nwachukwu, J. C.; Srinivasan, S.; Nettles, C. C.; Izard, T.; Jin, z.; Boregowda, S.; Phinney, D.; Elemento, O.; Liu, X.; Ortlund, E. A.; Houtman, R.; Stavreva, D.; Hager, G.; Kamencka, T.; Kojetin, D.; Nettles, K. W.
10.1101/2020.06.15.153270 — pharmacology and toxicology — Posted on 2020-10-16
2103 A pan-cancer metabolic atlas of the tumor microenvironment
Rohatgi, N.; Ghoshdastider, U.; Baruah, P.; Skanderup, A. J.
10.1101/2020.10.16.342519 — cancer biology — Posted on 2020-10-16
2104 Quantifying the Influence of Mutation Detection on Tumour Subclonal Reconstruction
Liu, L. Y.; Bhandari, V.; Salcedo, A.; Espiritu, S. M.; Morris, Q. D.; Kislinger, T. R.; Boutros, P. C.
10.1101/418780 — cancer biology — Posted on 2020-10-16
2105 Single cell transcriptome sequencing on the Nanopore platform with ScNapBar
Wang, Q.; Boenigk, S.; Boehm, V.; Gehring, N. H.; Altmueller, J.; Dieterich, C.
10.1101/2020.10.16.342626 — bioinformatics — Posted on 2020-10-16
2109 The effect of temperature and humidity on the stability of SARS-CoV-2 and other enveloped viruses
Morris, D. H.; Yinda, K. C. H.; Gamble, A.; Rossine, F. W.; Huang, Q.; Bushmaker, T.; Fischer, R. J.; Matson, M. J.; van Doremalen, N.; Vikesland, P. J.; Marr, L. C.; Munster, V.; Lloyd-Smith, J. O.
10.1101/2020.10.16.341883 — microbiology — Posted on 2020-10-16
2110 A Novel Class of Azoles with potent Anti-Leishmanial activity
Mathur, T.; Kumar, M.; Barman, T. K.; Raj, S. V.; Upadhyay, D. J.; Verma, A. K.
10.1101/2020.10.16.342329 — microbiology — Posted on 2020-10-16
2116 Modeling airway dysfunction in asthma using synthetic mucus biomaterials
Song, D.; Iverson, E.; Kaler, L.; Bader, S.; Scull, M. A.; Duncan, G. A.
10.1101/2020.10.16.342766 — bioengineering — Posted on 2020-10-16
2119 Neural inflammation alters synaptic plasticity probed by 10 Hz repetitive magnetic stimulation
Lenz, M.; Eichler, A.; Kruse, P.; Strehl, A.; Rodriguez-Rozada, S.; Goren, I.; Yogev, N.; Frank, S.; Waisman, A.; Deller, T.; Jung, S.; Maggio, N.; Vlachos, A.
10.1101/2020.10.16.336065 — neuroscience — Posted on 2020-10-16
2120 Neural correlates of hand-object congruency effects during action planning
Zhang, Z.; Nelissen, N.; Zeidman, P.; Filippini, N.; Diedrichsen, J.; Friston, K.; Bracci, S.; Rounis, E.
10.1101/2020.10.16.342147 — neuroscience — Posted on 2020-10-16
2121 APP accumulates around dense-core amyloid plaques with presynaptic proteins in Alzheimer's disease brain
Jorda-Siquier, T.; Petrel, M.; Kouskoff, V.; Cordelieres, F.; Frykman, S.; Muller, U.; Mulle, C.; Barthet, G.
10.1101/2020.10.16.342196 — neuroscience — Posted on 2020-10-16
2126 Genomics-accelerated discovery of diverse fungicidal bacteria
Biggs, M. B.; Craig, K.; Gachango, E.; Ingham, D.; Twizeyimana, M.
10.1101/2020.10.16.343004 — microbiology — Posted on 2020-10-16
2128 Deep-learning based fully automatic segmentation of the globus pallidus interna and externa using ultra-high 7 Tesla MRI
Solomon, O.; Palnitkar, T.; Patriat, R.; Braun, H.; Aman, J.; Park, M.; Vitek, J.; Sapiro, G.; Harel, N.
10.1101/2020.10.15.341578 — neuroscience — Posted on 2020-10-16
2133 A drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent local relapse and treat established brain metastasis
Zhu, L.; Yebra, N.; Miarka, L.; Hernandez-Encinas, E.; Blanco-Aparicio, C.; Martinez, S.; Soffietti, R.; Bertero, L.; Cassoni, P.; Weiss, T.; Munoz, J.; Sepulveda, J. M.; Perez-Nunez, A.; Hernandez-Lain, A.; Ruano, Y.; Toldos, O.; Caleiras, E.; Megias, D.; Grana-Castro, O.; Nör, C.; Taylor, M. D.; Cusso, L.; Desco, M.; Weller, M.; Pastor, J.; Valiente, M.
10.1101/2020.10.16.329243 — cancer biology — Posted on 2020-10-16
2135 A paired liver biopsy and plasma proteomics study reveals circulating biomarkers for alcohol-related liver disease
Niu, L.; Thiele, M.; Geyer, P. E.; Rasmussen, D. N.; Webel, H. E.; Santos, A.; Gupta, R.; Meier, F.; Strauss, M.; Kjaergaard, M.; Lindvig, K.; Jacobsen, S.; Rasmussen, S.; Hansen, T.; Krag, A.; Mann, M.
10.1101/2020.10.16.337592 — biochemistry — Posted on 2020-10-16
2139 Mapping calcium dynamics in a developing tubular structure.
Hoyer, J.; Saba, M.; Dondorp, D.; Kolar, K.; Esposito, R.; Chatzigeorgiou, M.
10.1101/2020.10.16.342535 — developmental biology — Posted on 2020-10-16
2145 Non-rodent mammalian zygotes assemble dual spindles despite the presence of paternal centrosomes
Schneider, I.; de Ruijter-Villani, M.; Hossain, M. J.; Stout, T. A. E.; Ellenberg, J.
10.1101/2020.10.16.342154 — cell biology — Posted on 2020-10-16
2146 Multivalency transforms SARS-CoV-2 antibodies into broad and ultrapotent neutralizers
Rujas, E.; Kucharska, I.; Tan, Y. Z.; Benlekbir, S.; Cui, H.; Zhao, T.; Wasney, G. A.; Budylowski, P.; Guvenc, F.; Newton, J. C.; Sicard, T.; Semesi, A.; Muthuraman, K.; Nouanesengsy, A.; Prieto, K.; Bueler, S. A.; Youssef, S.; Liao-Chan, S.; Glanville, J.; Christie-Holmes, N.; Mubareka, S.; Gray-Owen, S. D.; Rubinstein, J. L.; Treanor, B.; Julien, J.-P.
10.1101/2020.10.15.341636 — molecular biology — Posted on 2020-10-16
2147 Duple extinguishment of COVID-19: single compound synergized inhibition of SARS-CoV-2 replication and direct suppression of inflammatory cytokines in vitro/vivo
Gao, X.; Gong, Y.; Tan, W.; Jiang, H.; Qi, J.; Zhao, J.; Sun, B.; Gao, X.; Gao, X.; Cao, P.; He, B.; Fan, J.; Dong, Y.; Gao, F.; Yuan, Q.; Gao, Y.; Zhao, W.; Zhang, C.; Du, Z.; Ye, F.; He, Z.
10.1101/2020.10.16.342097 — microbiology — Posted on 2020-10-16
2149 Early induction of SARS-CoV-2 specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients
Tan, A. T.; Linster, M.; Tan, C.; Le Bert, N.; Chia, W.; Kunasegaran, K.; Zhuang, Y.; Tham, C. Y.; Chia, A.; Smith, G. J.; Young, B. E.; Kalimuddin, S.; Low, J. G.; Lye, D.; Wang, L.-F.; Bertoletti, A.
10.1101/2020.10.15.341958 — immunology — Posted on 2020-10-16
2150 Antibody Response to a Nucleocapsid Epitope as a Marker for COVID-19 Disease Severity
Sen, S.; Sanders, E. C.; Gabriel, K. N.; Miller, B. M.; Isoda, H. M.; Salcedo, G. S.; Garrido, J. E.; Dyer, R. P.; Nakajima, R.; Jain, A.; Santos, A. M.; Bhuvan, K.; Tifrea, D. F.; Ricks-Oddie, J. L.; Felgner, P. L.; Edwards, R. A.; Majumdar, S.; Weiss, G. A.
10.1101/2020.10.15.341743 — immunology — Posted on 2020-10-16
2152 Peptide vaccine candidate mimics the heterogeneity of natural SARS-CoV-2 immunity in convalescent humans and induces broad T cell responses in mice models
Somogyi, E.; Csiszovszki, Z.; Molnar, L.; Lorincz, O.; Toth, J.; Pattijn, S.; Schockaert, J.; Mazy, A.; Miklos, I.; Pantya, K.; Pales, P.; Toke, E. R.
10.1101/2020.10.16.339937 — immunology — Posted on 2020-10-16
2154 Metalloprotease Gp63 targeting novel glycoside exhibits potential antileishmanial activity
Chakrabarty, A.; Narayana, C.; Joshi, N.; Garg, S.; Garg, L.; Sagar, R.; Pati, S.; singh, s.
10.1101/2020.09.11.292920 — pharmacology and toxicology — Posted on 2020-10-16
2157 Bromodomain Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV2 Infection in Pre-Clinical Models
Mills, R. J.; Humphrey, S. J.; Fortuna, P. R.; Quaife-Ryan, G. A.; Lor, M.; Ruraraju, R.; Rawle, D. J.; Le, T.; Zhao, W.; Lee, L.; Mackenzie-Kludas, C.; Mehdiabadi, N. R.; Devilee, L.; Voges, H. K.; Reynolds, L. T.; Krumeich, S.; Mathieson, E.; Abu-Bonsrah, D.; Karavendzas, K.; Griffen, B.; Titmarsh, D. M.; Elliott, D. A.; McMahon, J. H.; Suhrbier, A.; Subbarao, K.; Porrello, E. R.; Smyth, M. J.; Engwerda, C. R.; MacDonald, K. P.; Bald, T.; James, D. E.; Hudson, J. E.
10.1101/2020.08.23.258574 — cell biology — Posted on 2020-10-16
2158 SPF45/RBM17-dependent, but not U2AF-dependent, splicing in human short introns
Fukumura, K.; Yoshimoto, R.; Sperotto, L.; Kang, H.-S.; Hirose, T.; Inoue, K.; Sattler, M.; Mayeda, A.
10.1101/784868 — molecular biology — Posted on 2020-10-16
2159 Quantitative assessment of NCLDV-host interactions predicted by co-occurrence analyses
Meng, L.; Endo, H.; Blanc-Mathieu, R.; Hernandez-Velazquez, R.; Kaneko, H.; Ogata, H.
10.1101/2020.10.16.342030 — microbiology — Posted on 2020-10-16
2163 Multiomics data collection, visualization, and utilization for guiding metabolic engineering
Roy, S.; Radivojevic, T.; Forrer, M.; Marti, J. M.; Jonnalagadda, V.; Backman, T.; Morrell, W.; Plahar, H.; Kim, J.; Hillson, N.; Martin, H. G.
10.1101/2020.10.15.341909 — synthetic biology — Posted on 2020-10-16
2166 Spatiotemporal shifts in the role of floral traits in shaping tropical plant-pollinator interactions
Klomberg, Y.; Tropek, R.; Mertens, J. E.; Kobe, I. N.; Hodecek, J.; Raska, J.; Fominka, N. T.; Souto-Vilaros, D.; Janecek, S.
10.1101/2020.10.16.342386 — ecology — Posted on 2020-10-16
2168 DNA methylation is required to maintain DNA replication timing precision and 3D genome integrity
Du, Q.; Smith, G. C.; Luu, P. L.; Ferguson, J. M.; Armstrong, N. J.; Caldon, C. E.; Campbell, E.; Nair, S. S.; Zotenko, E.; Gould, C. M.; Buckley, M.; Kaczorowski, D.; Barton, K.; Deveson, I. W.; Smith, M. A.; Powell, J. E.; Skvortsova, K.; Stirzaker, C.; Achinger-Kawecka, J.; Clark, S. J.
10.1101/2020.10.15.338855 — molecular biology — Posted on 2020-10-16
2169 The in vitro antiviral activity of the anti-hepatitis C virus (HCV) drugs daclatasvir and sofosbuvir against SARS-CoV-2
Sacramento, C. Q.; Fintelman-Rodrigues, N.; Temerozo, J. R.; Da Silva, A. d. P. D.; da Silva Gomes Dias, S.; Ferreira, A. C.; da Silva, C. d. S.; Mattos, M.; Pao, C. R. R.; de Freitas, C. S.; Cardoso Soares, V.; Hoelz, L. V. B.; Fernandes, T. V. A.; Branco, F. S. C.; Bastos, M. M.; Boechat, N.; Saraiva, F. B.; Ferreira, M. A.; Rajoli, R. K. R.; Pedrosa, C. S. G.; Vitoria, G.; Souza, L. R. Q.; Goto-Silva, L.; Guimaraes, M. Z.; Rehen, S. K.; Owen, A.; Bozza, F. A.; Bou-Habib, D. C.; Bozza, P. T.; Souza, T. M. L.
10.1101/2020.06.15.153411 — microbiology — Posted on 2020-10-16
2170 Cellular events of acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates
Fahlberg, M. D.; Blair, R. V.; Doyle-Meyers, L. A.; Midkiff, C. C.; Zenere, G.; Russell-Lodrigue, K. E.; Monjure, C. J.; Haupt, E. H.; Penney, T. P.; Lehmicke, G.; Threeton, B. M.; Golden, N.; Datta, P. K.; Roy, C. J.; Bohm, R. P.; Maness, N. J.; Fischer, T.; Rappaport, J.; Vaccari, M.
10.1101/2020.07.21.213777 — immunology — Posted on 2020-10-16
2171 Experimental and natural evidence of SARS-CoV-2 infection-induced activation of type I interferon responses
Banerjee, A.; El-Sayes, N.; Budylowski, P.; Richard, D.; Maan, H.; Aguiar, J.; Baid, K.; D'Agostino, M. R.; Ang, J. C.; Tremblay, B. J.- M.; Afkhami, S.; Karimzadeh, M.; Irving, A. T.; Yip, L.; Ostrowski, M. A.; Hirota, J. A.; Kozak, R.; Capellini, T. D.; Miller, M. S.; Wang, B.; Mubareka, S.; McGeer, A. J.; McArthur, A. G.; Doxey, A. C.; Mossman, K.
10.1101/2020.06.18.158154 — immunology — Posted on 2020-10-16
2172 a-Synuclein strains influence multiple system atrophy via central and peripheral mechanisms
Murazabal, T. T.; Van der Perren, A.; Coens, A.; Barber, A. J.; Camacho-Garcia, S.; Stefanova, N.; Melki, R.; Baekelandt, V.; Peelaerts, W.
10.1101/2020.10.16.342089 — neuroscience — Posted on 2020-10-16
2173 Large-scale analysis of Drosophila core promoter function using synthetic promoters
Zhan, Q.; Jung, C.; Bandilla, P.; Ludwig, C.; Heron, M.; Kiesel, A. S.; Philippou-Massier, J.; Nikolov, M.; Renna, A.; Schnepf, M.; Unnerstall, U.; Soeding, J.; Gaul, U.
10.1101/2020.10.15.339325 — systems biology — Posted on 2020-10-16
2177 Multi-omics integration analysis identifies novel genes for alcoholism with potential link to neurodegenerative diseases
Kapoor, M.; Chao, M.; Johnson, E. C.; Novikova, G.; Lai, D.; Meyers, J.; Schulman, J.; Nurnberger, J. I.; Porjesz, B.; Liu, Y.; Collaborative Study on Genetics of Alcoholism, ; Foroud, T.; Edenberg, H. J.; Marcora, E.; Agrawal, A.; Goate, A. M.
10.1101/2020.10.15.341750 — genomics — Posted on 2020-10-16
2179 A wild Cucurbita genome reveals the role of structural variants and introgression in domestication
Barrera-Redondo, J.; Sanchez-de la Vega, G.; Aguirre-Liguori, J. A.; Castellanos-Morales, G.; Gutierrez-Guerrero, Y. T.; Aguirre-Dugua, X.; Aguirre-Planter, E.; Tenaillon, M. I.; Lira-Saade, R.; Eguiarte, L. E.
10.1101/2020.10.15.341990 — evolutionary biology — Posted on 2020-10-16
2183 The role of behavioural flexibility in primate diversification
Creighton, M. J. A.; Greenberg, D. A.; Reader, S. M.; Mooers, A. O.
10.1101/2020.10.15.341859 — evolutionary biology — Posted on 2020-10-16
2184 DOT1L primarily acts as a transcriptional repressor in hematopoietic progenitor cells
Borosha, S.; Rtari, A.; Housami, S. M.; Rai, S.; Ghosh, S.; Malcom, C. A.; Chakravarthi, V. P.; Vivian, J. L.; Fields, T. A.; Rumi, M. A.; Fields, P. E.
10.1101/2020.10.15.341255 — developmental biology — Posted on 2020-10-16
2187 Temporal changes in metabolism late in seed development affect biomass composition in soybean
Kambhampati, S.; Aznar-Moreno, J. A.; Bailey, S. R.; Arp, J. J.; Chu, K.; Bilyeu, K. D.; Durrett, T. P.; Allen, D. K.
10.1101/2020.10.15.341339 — plant biology — Posted on 2020-10-16
2188 Computational and experimental analyses of mitotic chromosome formation pathways in fission yeast
Gerguri, T.; Fu, X.; Kakui, Y.; Khatri, B. S.; Barrington, C.; Bates, P. A.; Uhlmann, F.
10.1101/2020.10.15.341305 — biophysics — Posted on 2020-10-16
2193 Double-layer flexible neuronal probe with closely spaced electrodes for high-density in vivo brain recordings
Pimenta, S.; Rodrigues, J. A.; Machado, F.; Ribeiro, J. F.; Maciel, M. J.; Bondarchuk, O.; Monteiro, P.; Gaspar, J.; Correia, J. H.; Jacinto, L.
10.1101/2020.10.15.341263 — bioengineering — Posted on 2020-10-16
2195 A multi-platform reference for somatic structural variation detection
Espejo Valle-Inclan, J.; Besselink, N. J. M.; de Bruijn, E.; Cameron, D. L.; Ebler, J.; Kutzera, J.; van Lieshout, S.; Marschall, T.; Nelen, M.; Wing Chun Pang, A.; Priestley, P.; Renkens, I.; Roemer, M. G. M.; van Roosmalen, M. J.; Wenger, A. M.; Ylstra, B.; Fijneman, R. J. A.; Kloosterman, W. P.; Cuppen, E.
10.1101/2020.10.15.340497 — genomics — Posted on 2020-10-16
2197 CASB: A concanavalin A-based sample barcoding strategy for single-cell sequencing
Fang, L.; Li, G.; Zhu, Q.; Cui, H.; Li, Y.; Sun, Z.; Liang, W.; Hu, Y.; Chen, W.
10.1101/2020.10.15.340844 — genomics — Posted on 2020-10-16
2198 Persistence of plant-mediated microbial soil legacy effects in soil and inside roots
Hannula, E. S.; Heinen, R.; Huberty, M.; Steinauer, K.; De Long, J. R.; Jongen, R.; Bezemer, M. T.
10.1101/2020.10.15.340620 — ecology — Posted on 2020-10-16
2206 Physical modeling of a sliding clamp mechanism for the spreading of ParB at short genomic distance from bacterial centromere sites
Walter, J.-C.; Rech, J.; Walliser, N.-O.; Dorignac, J.; Geniet, F.; Palmeri, J.; Parmeggiani, A.; Bouet, J.-Y.
10.1101/2020.07.22.213413 — systems biology — Posted on 2020-10-16
2207 Proteome constraints reveal targets for improving microbial fitness in nutrient-rich environments
Chen, Y.; Pelt-KleinJan, E. v.; Olst, B. v.; Douwenga, S.; Boeren, S.; Bachmann, H.; Molenaar, D.; Nielsen, J.; Teusink, B.
10.1101/2020.10.15.340554 — systems biology — Posted on 2020-10-16
2208 Substitutional landscape of a split fluorescent protein fragment
Antonescu, O. N.; Rasmussen, A.; Damm, N. A. M.; Heidemann, D. F.; Popov, R.; Nesterov-Mueller, A.; Johansson, K. E.; Winther, J. R.
10.1101/2020.05.20.105668 — synthetic biology — Posted on 2020-10-16
2209 Early maternal loss affects diurnal cortisol slopes in immature but not mature wild chimpanzees
Girard-Buttoz, C.; Tkaczynski, P. J.; Liran, S.; Fedurek, P.; Gomes, C.; Loehrich, T.; Manin, V.; Preis, A.; Vale, P.; Deschner, T.; Wittig, R.; Crockford, C.
10.1101/2020.10.15.340893 — physiology — Posted on 2020-10-16
2210 Fibrous caps in atherosclerosis form by Notch-dependent mechanisms common to arterial media development
Martos Rodriguez, C. J.; Albarran-Juarez, J.; Morales Cano, D.; Caballero, A.; MacGrogan, D.; de la Pompa, J. L.; Carramolino, L.; Bentzon, J. F.
10.1101/2020.09.28.316984 — pathology — Posted on 2020-10-16
2218 Soil chemical legacies trigger species-specific and context-dependent root responses in later arriving plants
Delory, B. M.; Schempp, H.; Spachmann, S. M.; Störzer, L.; van Dam, N. M.; Temperton, V. M.; Weinhold, A.
10.1101/2020.09.01.276840 — ecology — Posted on 2020-10-16
2219 POLArIS, a versatile probe for molecular orientation, revealed actin filaments associated with microtubule asters in early embryos
Sugizaki, A.; Sato, K.; Chiba, K.; Saito, K.; Kawagishi, M.; Tomabechi, Y.; Mehta, S. B.; Ishii, H.; Sakai, N.; Shirouzu, M.; Tani, T.; Terada, S.
10.1101/2020.06.20.116178 — cell biology — Posted on 2020-10-16
2220 Islet Gene View - a tool to facilitate islet research
Asplund, O.; Storm, P.; Chandra, V.; Ottosson-Laakso, E.; Hatem, G.; Mansour-Aly, D.; Krus, U.; Ibrahim, H.; Ahlqvist, E.; Tuomi, T.; Renstrom, E.; Korsgren, O.; Wierup, N.; Wollheim, C.; Artner, I.; Mulder, H.; Hansson, O.; Otonkoski, T.; Groop, L.; Prasad, R. B.
10.1101/435743 — molecular biology — Posted on 2020-10-16
2223 Soluble mannose receptor induces pro-inflammatory macrophage activation and metaflammation
Embgenbroich, M.; van der Zande, H. J.; Hussaarts, L.; Schulte-Schrepping, J.; Pelgrom, L. R.; Garcia-Tardon, N.; Schlautmann, L.; Stoetzel, I.; Handler, K.; Lambooij, J. M.; Zawistowska-Deniziak, A.; Hoving, L.; de Ruiter, K.; Wijngaarden, M.; Pijl, H.; Willems van Dijk, K.; Everts, B.; van Harmelen, V.; Yazdanbakhsh, M.; Schultze, J. L.; Guigas, B.; Burgdorf, S.
10.1101/2020.09.29.315598 — immunology — Posted on 2020-10-16
2224 RTP801 Is A Key Modulator For Motor Learning
Perez-Sisques, L.; Martin-Flores, N.; Masana, M.; Solana, J.; Llobet, A.; Romani-Aumedes, J.; Canal, M.; Campoy, G.; Garcia, E.; Sanchez, N.; Fernandez, S.; Gilbert, J. P.; Rodriguez, M. J.; Man, H.; Feinstein, E.; Williamson, D.; Soto, D.; Gasull, X.; Alberch, J.; Malagelada, C.
10.1101/2020.10.15.340851 — neuroscience — Posted on 2020-10-16
2228 In Pursuit of a Better Broiler: Growth, Efficiency and Mortality of 16 Strains of Broiler Chickens
Torrey, S.; Mohammadigheisar, M.; Nascimento dos Santos, M.; Rothschild, D.; Dawson, L. C.; Liu, Z.; Kiarie, E.; Edwards, A. M.; Mandell, I.; Karrow, N. A.; Tulpan, D.; Widowski, T. M.
10.1101/2020.10.15.341586 — physiology — Posted on 2020-10-16
2229 Jaw Kinematics and Tongue Protraction-Retraction during Chewing and Drinking in the Pig
Olson, R. A.; Montuelle, S. J.; Chadwell, B. A.; Curtis, H.; Williams, S. H.
10.1101/2020.08.22.261602 — physiology — Posted on 2020-10-16
2231 High dimensional immunotyping of the obese tumor microenvironment reveals model specific adaptation
Wogsland, C. E.; Lien, H. E.; Pedersen, L.; Hanjra, P.; Grondal, S. M.; Brekken, R.; Lorens, J. B.; Halberg, N.
10.1101/2020.10.14.338806 — cancer biology — Posted on 2020-10-16
2232 Robotic Multi-Probe-Single-Actuator Inchworm Neural Microdrive
Smith, R. D.; Kolb, I.; Tanaka, S.; Lee, A. K.; Harris, T. D.; Barbic, M.
10.1101/2020.10.13.338137 — bioengineering — Posted on 2020-10-16
2233 SARS-CoV-2 S protein ACE2 interaction reveals novel allosteric targets
Anand, G. S.; Palur, R.; Tulsian, N. K.; Samsudin, F.; Qian, X.; Purushotorman, K.; Yue, G.; McQueen, M. K.; Lescar, J.; Bond, P.; McAry, P. A.
10.1101/2020.10.13.337212 — biochemistry — Posted on 2020-10-16
2236 Functional repertoire convergence of distantly related eukaryotic plankton lineages revealed by genome-resolved metagenomics
Delmont, T. O.; Gaia, M.; Hinsinger, D. D.; Fremont, P.; Fernandez Guerra, A.; Eren, A. M.; Vanni, C.; Kourlaiev, A.; d'Agata, L.; Clayssen, Q.; Villar, E.; Labadie, K.; Cruaud, C.; Poulain, J.; Da Silva, C.; Wessner, M.; Noel, B.; Aury, J.-M.; Coordinators, T. O.; de Vargas, C.; Bowler, C.; Karsenti, E.; Pelletier, E.; Wincker, P.; Jaillon, O.
10.1101/2020.10.15.341214 — microbiology — Posted on 2020-10-16
2237 Performances of NeuMoDx, a random-access system for HBV-DNA and HCV-RNA quantification
Besombes, J.; Pronier, C.; Lefevre, C.; Lagathu, G.; Maillard, A.; Grolhier, C.; Thibault, V.
10.1101/2020.10.14.340398 — microbiology — Posted on 2020-10-16
2238 Ongoing Adaptive Evolution and Globalization of Sars-Cov-2
Rochman, N. D.; Wolf, Y. I.; Faure, G.; Zhang, F.; Koonin, E. V.
10.1101/2020.10.12.336644 — microbiology — Posted on 2020-10-16
2240 Neurophysiological coding of statistical and deterministic rule information
Takacs, A.; Kobor, A.; Kardos, Z.; Janacsek, K.; Horvath, K.; Beste, C.; Nemeth, D.
10.1101/2020.10.14.338913 — neuroscience — Posted on 2020-10-16
2242 High complexity cellular barcoding and clonal tracing reveals stochastic and deterministic parameters of radiation resistance
Nowrouzi, A.; Wursthorn, A.; Schwager, C.; Kurth, I.; Peitzsch, C.; Herold-Mende, C.; Baumann, M.; Debus, J.; Abdollahi, A.
10.1101/2020.10.13.337519 — systems biology — Posted on 2020-10-16
2243 Androgen regulation of bowel function in mice and humans
Rastelli, D.; Robinson, A.; Matthews, L. T.; Perez, K.; Dan, W.; Yim, P.; Mixer, M.; Prochera, A.; Hassan, R.; Hall, K.; Ballou, S.; Nee, J.; Lembo, A.; Rao, M.
10.1101/2020.10.15.341081 — neuroscience — Posted on 2020-10-15
2245 Nanoscape, a data-driven 3D real-time interactive virtual cell environment
Kadir, S. R.; Lilja, A.; Gunn, N.; Strong, C.; Hughes, R. T.; Bailey, B. J.; Rae, J.; Parton, R. G.; McGhee, J.
10.1101/2020.10.15.340778 — scientific communication and education — Posted on 2020-10-15
2254 Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites
Borschiwer, M.; Bothe, M.; Kibar, G.; Fuchs, A.; Schoene, S.; Prekovic, S.; Mayayo Peralta, I.; Chung, H.-R.; Zwart, W. H.; Helsen, C.; Claessens, F.; Meijsing, S. H.
10.1101/2020.10.15.340877 — genomics — Posted on 2020-10-15
2256 Selfing is the safest sex for Caenorhabditis tropicalis
Noble, L. M.; Yuen, J.; Stevens, L.; Moya, N.; Persaud, R. S.; Moscatelli, M. A.; Jackson, J. L.; Zhang, G.; Chitrakar, R.; Baugh, R.; Braendle, C.; Andersen, E. C.; Seidel, H. S.; Rockman, M. V.
10.1101/2020.08.07.242032 — evolutionary biology — Posted on 2020-10-15
2261 Brain mapping across 16 autism mouse models reveals a spectrum of functional connectivity subtypes
Zerbi, V.; Pagani, M.; Markicevic, M.; Matteoli, M.; Pozzi, D.; Fagiolini, M.; Bozzi, Y.; Galbusera, A.; Scattoni, M. L.; Provenzano, G.; Banerjee, A.; Helmchen, F.; Basson, A.; Ellegood, J.; Lerch, J.; Rudin, M.; Gozzi, A.; Wenderoth, N.
10.1101/2020.10.15.340588 — neuroscience — Posted on 2020-10-15
2263 Genes derived from ancient polyploidy have higher genetic diversity and are associated with domestication in Brassica rapa
Qi, X.; An, H.; Hall, T. E.; Di, C.; Blischak, P.; McKibben, M. T. W.; Hao, Y.; Conant, G. C.; Pires, J. C.; Barker, M. S.
10.1101/842351 — plant biology — Posted on 2020-10-15
2270 MCM complexes are barriers that restrict cohesin-mediated loop extrusion
Dequeker, B. J. H.; Brandao, H. B.; Scherr, M. J.; Gassler, J.; Powell, S.; Gaspar, I.; Flyamer, I. M.; Tang, W.; Stocsits, R.; Davidson, I. F.; Peters, J.-M.; Duderstadt, K. E.; Mirny, L. A.; Tachibana, K.
10.1101/2020.10.15.340356 — cell biology — Posted on 2020-10-15
2271 Hypoxia pathway proteins regulate the synthesis and release of epinephrine in the mouse adrenal gland
Watts, D.; Bechmann, N.; Meneses, A.; Poutakidou, I. K.; Kaden, D.; Conrad, C.; Krueger, A.; Stein, J.; El-Armouche, A.; Chavakis, T.; Eisenhofer, G.; Peitzsch, M.; Wielockx, B.
10.1101/2020.10.15.340943 — molecular biology — Posted on 2020-10-15
2273 Two-target quantitative PCR to predict library composition for shallow shotgun sequencing
Cho, M. Y.; Oliva, M.; Spreafico, A.; Chen, B.; Wei, X.; Choi, Y.; Kaul, R.; Siu, L. L.; Coburn, B.; Schneeberger, P. H. H.
10.1101/2020.09.21.304006 — microbiology — Posted on 2020-10-15
2274 Validation of a novel multiplex real-time PCR assay for Trypanosoma cruzi detection and quantification in acai pulp
Finamore-Araujo, P.; Faier-Pereira, A.; Ramon do Nascimento Brito, C.; Gomes Peres, E.; Kazumy de Lima Yamaguchi, K.; Trotta Barroso Ferreira, R.; Moreira, O. C.
10.1101/2020.10.15.340984 — microbiology — Posted on 2020-10-15
2279 Numerical Instabilities in Analytical Pipelines Lead to Large and Meaningful Variability in Brain Networks
Kiar, G.; Chatelain, Y.; de Oliveira Castro, P.; Petit, E.; Rokem, A.; Varoquaux, G.; Misic, B.; Evans, A. C.; Glatard, T.
10.1101/2020.10.15.341495 — neuroscience — Posted on 2020-10-15
2280 Neuroprotective pentapeptide, CN-105, improves outcomes in translational models of intracerebral hemorrhage
Wang, H.; Faw, T. D.; Lin, Y.; Huang, S.; Venkatraman, T. N.; Cantillana, V.; Lascola, C. D.; James, M. L.; Laskowitz, D. T.
10.1101/2020.10.15.339184 — neuroscience — Posted on 2020-10-15
2282 A collaborative resource platform for non-human primate neuroimaging
Messinger, A.; Sirmpilatze, N.; Heuer, K.; Loh, K. K.; Mars, R.; Sein, J.; Xu, T.; Glen, D.; Jung, B.; Seidlitz, J.; Taylor, P.; Toro, R.; Garza-Villareal, E.; Sponheim, C.; Wang, X.; Benn, A.; Cagna, B.; Dadarwal, R.; Evrard, H.; Garcia-Saldivar, P.; Giavasis, S.; Hartig, R.; Lepage, C.; Liu, C.; Majka, P.; Merchant, H.; Milham, M.; Rosa, M.; Tasserie, J.; Uhrig, L.; Margulies, D.; Klink, P. C.
10.1101/2020.07.31.230185 — neuroscience — Posted on 2020-10-15
2283 Influences of time of day on generalization
Tandoc, M. C.; Bayda, M.; Poskanzer, C.; Cho, E.; Cox, R.; Stickgold, R.; Schapiro, A. C.
10.1101/2020.10.15.341826 — neuroscience — Posted on 2020-10-15
2284 Dopaminergic Co-transmission with Sonic Hedgehog Inhibits Expression of Abnormal Involuntary Movements
Malave, L.; Zuelke, D. R.; Uribe-Cano, S.; Starikov, L.; Rebholz, H.; Friedman, E.; Quin, C.; Li, Q.; Bezard, E.; Kottmann, A. H.
10.1101/2020.03.09.983759 — neuroscience — Posted on 2020-10-15
2285 Genome sequencing sheds light on the contribution of structural variants to Brassica oleracea diversification
Guo, N.; Wang, S.; Gao, L.; Liu, Y.; Duan, M.; Wang, G.; Li, J.; Yang, M.; Zong, M.; Han, S.; Pei, Y.; Borm, T.; Sun, H.; Miao, L.; Liu, D.; Yu, F.; Zhang, W.; Ji, H.; Zhu, C.; Xu, Y.; Bonnema, G. A. B.; Li, J.; Fei, Z.; Liu, F.
10.1101/2020.10.15.340224 — plant biology — Posted on 2020-10-15
2286 Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis
Zhang, Y.-Z.; Yuan, J.; Zhang, L.; Chen, C.-X.; Wang, Y.; Zhang, G.; Peng, L.; Xie, S.-S.; Jiang, J.; Zhu, J.-K.; Du, J.; Duan, C.-G.
10.1101/2020.10.15.341198 — plant biology — Posted on 2020-10-15
2291 An improved comprehensive strategy for deep and quantitative N-glycomics based on optimization of sample preparation, isotope-based data quality control and quantification, new N-glycan libraries and new algorithms
Guan, Y.; Hu, J.; Cao, W.; Cui, W.; Yang, F.; Krisp, C.; Lin, L.; Zhang, M.; Voss, H.; Schuster, R.; Yan, G.; Fuh, M. M.; Thaysen-Andersen, M.; H. Packer, N.; Shen, H.; Yang, P.; Schlüter, H.
10.1101/2020.10.15.340638 — biochemistry — Posted on 2020-10-15
2293 Mechanisms of allosteric and mixed mode aromatase inhibitors
Souza, S. A.; Held, A.; Lu, W.; Drouhard, B.; Avila, B.; Leyva-Montes, R.; Hu, M. G.; Miller, B. R.; Ng, H. L.
10.1101/2020.10.15.340745 — biochemistry — Posted on 2020-10-15
2294 High-throughput transcriptomic evaluation of per- and polyfluoroalkyl substances (PFAS) in primary human liver spheroids to inform read-across
Rowan-Carroll, A.; Readon, A.; Leingartner, K.; Gagne, R.; Williams, A.; Kuo, B.; Bourdon-lacombe, J.; Moffat, I.; Carrier, R.; Nong, A.; lorusso, l.; Ferguson, S. S.; Atlas, E.; Yauk, C.
10.1101/2020.10.15.341362 — genomics — Posted on 2020-10-15
2298 Hypoxia Drives Dihydropyrimidine Dehydrogenase Expression in Macrophages and Confers Chemoresistance in Colorectal Cancer
MALIER, M.; COURT, M.; GHARZEDDINE, K.; LAVERRIERE, M.; MARSILI, S.; THOMAS, F.; DECAENS, T.; ROTH, G.; MILLET, A.
10.1101/2020.10.15.341123 — cell biology — Posted on 2020-10-15
2299 Tau protein in smooth muscle cells and tissues
Shults, N. V.; Seeherman, S.; Sariipek, N. E.; Rybka, V.; Marcocci, L.; Gychka, S. G.; Ibrahim, Y. F.; Suzuki, Y. J.
10.1101/2020.10.15.341867 — cell biology — Posted on 2020-10-15
2300 Interaction Landscape of K29-Linked Ubiquitin Signaling Revealed by a Linkage-Specific Synthetic Antigen-Binding Fragment
Yu, Y.; Zheng, Q.; Erramilli, S. K.; Pan, M.; Park, S.; Xie, Y.; Li, J.; Fei, J.; Kossiakoff, A. A.; Liu, L.; Zhao, M.
10.1101/2020.10.15.341719 — cell biology — Posted on 2020-10-15
2301 Cas9-mediated Genome Editing Reveals a Significant Contribution of Calcium Signaling Pathways to Anhydrobiosis in Pv11
Miyata, Y.; Fuse, H.; Tokumoto, S.; Hiki, Y.; Deviatiiarov, R.; Yoshida, Y.; Yamada, T. G.; Cornette, R.; Gusev, O.; Shagimardanova, E.; Funahashi, A.; Kikawada, T.
10.1101/2020.10.15.340281 — molecular biology — Posted on 2020-10-15
2302 Coping with darkness: The adaptive response of marine picocyanobacteria to repeated light energy deprivation
Coe, A.; Biller, S.; Thomas, E.; Boulias, K.; Bliem, C.; Arellano, A.; Dooley, K.; Rasmussen, A. N.; LeGault, K.; O'Keefe, T. J.; Greer, E. L.; Chisholm, S. W.
10.1101/2020.10.15.341503 — microbiology — Posted on 2020-10-15
2304 AKT-like kinase promotes cell survival during nutritional stress in trypanosomatids
Diez-Mejia, A. F.; Pedroza, M. M.; Orrego, L. M.; Pulido, S. A.; Echeverry, M. C.; Rojas, M.; Soares, M. J.; Perez-Victoria, J. M.; Muskus, C. E.; Robledo, S. M.; Marin-Villa, M.; Varela-Miranda, R. E.
10.1101/2020.07.25.218644 — microbiology — Posted on 2020-10-15
2305 Design of SARS-CoV-2 RBD mRNA Vaccine Using Novel Ionizable Lipids
Elia, U.; Srinivas, R.; Dammes, N.; Bar-Haim, E.; Naidu, G. S.; Makdasi, E.; Cohen, O.; Peer, D.
10.1101/2020.10.15.341537 — immunology — Posted on 2020-10-15
2306 The Structures of Secretory and Dimeric Immunoglobulin A
Kumar Bharathkar, S.; Parker, B. W.; Malyutin, A.; Haloi, N.; Huey-Tubman, K. E.; Tajkhorshid, E.; Stadtmueller, B.
10.1101/2020.02.16.951780 — immunology — Posted on 2020-10-15
2310 Beta-cell specific insulin resistance promotes glucose-stimulated insulin hypersecretion
Skovso, S.; Panzhinskiy, E.; Kolic, J.; Dionne, D. A.; Dai, X.-Q.; Sharma, R. B.; Elghazi, L.; Cen, H. H.; Ellis, C. E.; Faulkner, K.; Marcil, S. A. M.; Overby, P.; Noursadeghi, N.; Hutchinson, D.; Hu, X.; Modi, H.; Wildi, J.; Botezelli, J. D.; Noh, H. L.; Suk, S.; Gablaski, B.; Bautista, A.; Kim, R.; Cras-Meneur, C.; Flibotte, S.; Sinha, S.; Luciani, D. S.; Nislow, C.; Rideout, E. J.; Cytrynbaum, E. N.; Kim, J.; Bernal-Mizrachi, E.; Alonso, L. C.; MacDonald, P. E.; Johnson, J. D.
10.1101/2020.10.15.338160 — physiology — Posted on 2020-10-15
2311 Autocrine Signaling by Receptor Tyrosine Kinases in Urothelial Carcinoma of the Bladder
Lee, Y. H.; Lee, M. M.; De Silva, D. M.; Roy, A.; Wright, C. E.; Wong, T. K.; Costello, R.; Olaku, O.; Grubb, R. L.; Agarwal, P. K.; Apolo, A. B.; Bottaro, D. P.
10.1101/2020.10.15.341206 — cancer biology — Posted on 2020-10-15
2313 Co-evolutionary Distance Prediction for Flexibility Prediction
Schwarz, D.; Georges, G.; Kelm, S.; Shi, J.; Vangone, A.; Deane, C. M.
10.1101/2020.10.15.340752 — bioinformatics — Posted on 2020-10-15
2316 Empirical variance component regression for sequence-function relationships
Zhou, J.; Wong, M. S.; Chen, W.-C.; Krainer, A. R.; Kinney, J. B.; McCandlish, D. M.
10.1101/2020.10.14.339804 — evolutionary biology — Posted on 2020-10-15
2317 Exploring cell-specific miRNA regulation with single-cell miRNA-mRNA co-sequencing data
Zhang, J.; Liu, L.; Xu, T.; Zhang, W.; Zhao, C.; Li, S.; Li, J.; Rao, N.; Le, T. D.
10.1101/2020.10.14.340299 — bioinformatics — Posted on 2020-10-15
2319 Behavioral and genomic sensory adaptations underlying the pest activity of Drosophila suzukii
Durkin, S. M.; Chakraborty, M.; Abrieux, A.; Lewald, K. M.; Gadau, A.; Svetec, N.; Peng, J.; Kopyto, M.; Chiu, J. C.; Emerson, J. J.; Zhao, L.
10.1101/2020.10.15.341594 — evolutionary biology — Posted on 2020-10-15
2320 Identification of subfunctionalized aggregate-remodeling J-domain proteins in plants
Tak, Y.; Lal, S. S.; Gopan, S.; Balakrishnan, M.; Verma, A. K.; Cole, S.; Brown, R.; Hayward, R.; Hines, J.; Sahi, C.
10.1101/2020.10.14.340331 — molecular biology — Posted on 2020-10-15
2323 Alzheimer's pathology is associated with dedifferentiation of functional memory networks in aging
Cassady, K.; Adams, J.; Chen, X.; Maass, A.; Harrison, T.; Landau, S.; Baker, S.; Jagust, W.
10.1101/2020.10.14.340075 — neuroscience — Posted on 2020-10-15
2324 Attention recruits frontal cortex in human infants
Ellis, C. T.; Skalaban, L. J.; Yates, T. S.; Turk-Browne, N. B.
10.1101/2020.10.14.340216 — neuroscience — Posted on 2020-10-15
2331 C9orf72- derived proline:arginine poly-dipeptides disturb cytoskeletal architecture
Shiota, T.; Nagata, R.; Kikuchi, S.; Nanaura, H.; Matsubayashi, M.; Nakanishi, M.; Kobashigawa, S.; Nagayama, K.; Sugie, K.; Yamashiro, Y.; Mori, E.
10.1101/2020.10.14.338566 — biochemistry — Posted on 2020-10-15
2332 Collection of 2429 constrained headshots of 277 volunteers for deep learning
Aoto, S.; Hangai, M.; Ueno-Yokohata, H.; Ueda, A.; Igarashi, M.; Ito, Y.; Tsukamoto, M.; Jinno, T.; Sakamoto, M.; Okazaki, Y.; Hasegawa, F.; Ogata-Kawata, H.; Namura, S.; Kojima, K.; Kikuya, M.; Matsubara, K.; Taniguchi, K.; Okamura, K.
10.1101/2020.10.14.337220 — animal behavior and cognition — Posted on 2020-10-15
2334 SM-Omics: An automated platform for high-throughput spatial multi-omics
Vickovic, S.; Loetstedt, B.; Klughammer, J.; Segerstolpe, A.; Rozenblatt-Rosen, O.; Regev, A.
10.1101/2020.10.14.338418 — genomics — Posted on 2020-10-15
2339 Targeted millisecond-scale activation of cells using non-invasive Sonogenetics
Duque, M.; Lee-Kubli, C.; Tufail, Y.; Magaram, U.; Lopez, J. M.; Edsinger, E.; Vasan, A.; Shiao, R.; Weiss, C.; Friend, J.; Chalasani, S. H.
10.1101/2020.10.14.338699 — neuroscience — Posted on 2020-10-15
2340 A connectome-wide functional signature of trait anger
Kim, M. J.; Elliott, M. L.; Knodt, A. R.; Hariri, A. R.
10.1101/2020.10.14.338863 — neuroscience — Posted on 2020-10-15
2342 A Boolean Model of the Formation of Tumour Associated Macrophages in an in-vitro Model of Chronic Lymphocytic Leukaemia
Marku, M.; Raynal, F.; Verstraete, N.; Domagala, M.; Madrid-Mencia, M.; Poupot, M.; Fournie, J.-J.; Ysebaert, L.; Pancaldi, V.
10.1101/2020.10.14.337642 — systems biology — Posted on 2020-10-15
2345 CRIMSON: An Open-Source Software Framework for Cardiovascular Integrated Modelling and Simulation
Arthurs, C. J.; Khlebnikov, R.; Melville, A.; Mar?an, M.; Gomez, A.; Dillon-Murphy, D.; Cuomo, F.; Silva Vieira, M.; Schollenberger, J.; Lynch, S. R.; Tossas-Betancourt, C.; Iyer, K.; Hopper, S.; Livingston, E.; Youssefi, P.; Noorani, A.; Ben Ahmed, S.; Nauta, F. J. H.; van Bakel, T. M. J.; Ahmed, Y.; van Bakel, P. A. J.; Mynard, J.; Di Achille, P.; Gharahi, H.; Lau, K. D.; Filonova, V.; Aguirre, M.; Nama, N.; Xiao, N.; Baek, S.; Garikipati, K.; Sahni, O.; Nordsletten, D.; Figueroa, C. A.
10.1101/2020.10.14.339960 — bioengineering — Posted on 2020-10-15
2348 Macroevolutionary Analyses Provide New Evidences of Phasmids Wings Evolution as a Reversible Process.
Forni, G.; Martelossi, J.; Valero, P.; Hennemann, F. H.; Conle, O.; Luchetti, A.; Mantovani, B.
10.1101/2020.10.14.336354 — evolutionary biology — Posted on 2020-10-15
2350 Impact of a tarsonemid prey mite and its fungal diet on the reproductive performance of a predatory mite
Vangansbeke, D.; Duarte, M. V. A.; Merckx, J.; Benavente, A.; Magowski, W. L.; Franca, S. C.; Bolckmans, K.; Wackers, F.
10.1101/2020.10.14.338889 — ecology — Posted on 2020-10-15
2352 Development of natural scene representation in primary visual cortex requires early postnatal experience
Kowalewski, N.; Kauttonen, J.; Stan, P. L.; Jeon, B. B.; Fuchs, T.; Chase, S. M.; Lee, T. S.; Kuhlman, S.
10.1101/2020.10.14.338897 — neuroscience — Posted on 2020-10-15
2355 Quantitative Assays Reveal Cell Fusion at Minimal Levels of SARS-CoV-2 Spike Protein and Fusion-from-Without
Theuerkauf, S. A.; Michels, A.; Riechert, V.; Maier, T. J.; Flory, E.; Cichutek, K.; Buchholz, C. J.
10.1101/2020.10.15.340604 — microbiology — Posted on 2020-10-15
2356 Integrated characterization of SARS-CoV-2 genome, microbiome, antibiotic resistance and host response from single throat swabs
Lu, B.; Yan, Y.; Dong, L.; Han, L.; Liu, Y.; Yu, J.; Chen, J.; Yi, D.; Zhang, M.; Wang, C.; Wang, R.; Wang, D.; Wei, H.; Liu, D.; Yi, C.
10.1101/2020.10.15.340794 — microbiology — Posted on 2020-10-15
2357 Systematic analysis of innate immune antagonism reveals vulnerabilities of SARS-CoV-2
Hayn, M.; Hirschenberger, M.; Koepke, L.; Straub, J. H.; Nchioua, R.; Klute, S.; Prelli Bozzo, C.; Aftab, W.; Zech, F.; Conzelmann, C.; Mueller, J. A.; Srinivasachar Badarinarayan, S.; Stuerzel, C. M.; Forne, I.; Stenger, S.; Conzelmann, K.-K.; Muench, J.; Sauter, D.; Imhof, A.; Kirchhoff, F.; Sparrer, K. M. J.
10.1101/2020.10.15.340612 — microbiology — Posted on 2020-10-15
2358 Evidence of antigenic imprinting in sequential Sarbecovirus immunization
Lv, H.; So, R. T. Y.; Yuan, M.; Liu, H.; Lee, C.-C. D.; Yip, G. K.; Ng, W. W.; Wilson, I. A.; Peiris, J. S. M.; Wu, N. C.; Mok, C. K. P.
10.1101/2020.10.14.339465 — immunology — Posted on 2020-10-15
2359 Strengthening marine amphipod DNA barcode libraries for environmental monitoring
PrasannaKumar, C.; Manikantan, G.; Vijaylaxmi, J.; Gunalan, B.; Manokaran, S.; Pugazhvendan, S. R.
10.1101/2020.08.26.268896 — zoology — Posted on 2020-10-15
2361 Multiplexed proteomics and imaging of resolving and lethal SARS-CoV-2 infection in the lung
Kalocsay, M.; Maliga, Z.; Nirmal, A. J.; Eisert, R. J.; Bradshaw, G. A.; Solomon, I. H.; Chen, Y.-A.; Pelletier, R. J.; Jacobson, C. A.; Mintseris, J.; Padera, R. F.; Martinot, A. J.; Barouch, D. H.; Santagata, S.; Sorger, P.
10.1101/2020.10.14.339952 — pathology — Posted on 2020-10-15
2362 Inhibition of SARS-CoV-2 viral entry in vitro upon blocking N- and O-glycan elaboration
Yang, Q.; Hughes, T. A.; Kelkar, A.; Yu, X.; Cheng, K.; Park, S. J.; Huang, W.-C.; Lovell, J. F.; Neelamegham, S.
10.1101/2020.10.15.339838 — biochemistry — Posted on 2020-10-15
2363 A high throughput RNA displacement assay for screening SARS-CoV-2 nsp10-nsp16 complex towards developing therapeutics for COVID-19
Perveen, S.; Khalili Yazdi, A.; Devkota, K.; Li, F.; Ghiabi, P.; Hajian, T.; Loppnau, P.; Bolotokova, A.; Vedadi, M.
10.1101/2020.10.14.340034 — biochemistry — Posted on 2020-10-15
2364 SLAP2 adaptor binding disrupts c-CBL autoinhibition to activate ubiquitin ligase function.
Wybenga-Groot, L. E.; Tench, A. J.; Simpson, C. D.; St. Germain, J.; Raught, B.; Moran, M. F.; McGlade, C. J.
10.1101/2020.06.18.159806 — molecular biology — Posted on 2020-10-15
2367 Cortical silencing results in paradoxical fMRI overconnectivity
Canella, C.; Rocchi, F.; Noei, S.; Gutierrez-Barragan, D.; Coletta, L.; Galbusera, A.; Vassanelli, S.; Pasqualetti, M.; Iurilli, G.; Panzeri, S.; Gozzi, A.
10.1101/2020.08.05.237958 — neuroscience — Posted on 2020-10-15
2368 Phosphorylation of Serine114 of the transcription factor ABSCISIC ACID INSENSITIVE 4 is essential for activity
Eisner, N.; Maymon, T.; Cancho Sanchez, E.; Bar-Zvi, D.; Brodsky, S.; Finkelstein, R. R.; Bar-Zvi, D.
10.1101/2020.08.14.250936 — plant biology — Posted on 2020-10-15
2373 Universal probabilistic programming: a powerful new approach to statistical phylogenetics
Ronquist, F.; Kudlicka, J.; Senderov, V.; Borgström, J.; Lartillot, N.; Lunden, D.; Murray, L.; Schön, T. B.; Broman, D.
10.1101/2020.06.16.154443 — evolutionary biology — Posted on 2020-10-15
2374 The negative adipogenesis regulator DLK1 is transcriptionally regulated by TIS7 (IFRD1) and translationally by its orthologue SKMc15 (IFRD2)
Vietor, I.; Cikes, D.; Piironen, K.; Gstir, R.; Tancevski, I.; Eller, P.; Demetz, E.; Hess, M.; Kuhn, V.; Degenhart, G.; Rainer, J.; Rozman, J.; Klingenspor, M.; Hrabe de Angelis, M.; Valovka, T.; Huber, L. A.
10.1101/719922 — cell biology — Posted on 2020-10-15
2379 A cis-regulatory element promoting increased transcription at low temperature in cultured ectothermic Drosophila cells
Bai, Y.; Caussinus, E.; Leo, S.; Bosshardt, F.; Myachina, F.; Rot, G.; Robinson, M. D.; Lehner, C. F.
10.1101/2020.10.15.340596 — cell biology — Posted on 2020-10-15
2380 Foxc1 establishes enhancer accessibility for craniofacial cartilage differentiation
Xu, P.; Yu, H. V.; Tseng, K.-C.; Flath, M.; Fabian, P.; Segil, N.; Crump, J. G.
10.1101/2020.10.15.340703 — molecular biology — Posted on 2020-10-15
2383 Sculpting New Visual Concepts into the Human Brain
Iordan, M. C.; Ritvo, V. J. H.; Norman, K. A.; Turk-Browne, N. B.; Cohen, J. D.
10.1101/2020.10.14.339853 — neuroscience — Posted on 2020-10-15
2384 The claustrum-medial prefrontal cortex network controls attentional set-shifting
Fodoulian, L.; Gschwend, O.; Huber, C.; Mutel, S.; Salazar, R.; Leone, R.; Renfer, J.-R.; Ekundayo, K.; Rodriguez, I.; Carleton, A.
10.1101/2020.10.14.339259 — neuroscience — Posted on 2020-10-15
2385 A structure-function substrate of memory for spatial configurations in medial and lateral temporal cortices
Tavakol, S.; Li, Q.; Royer, J.; Vos de Wael, R.; Lariviere, S.; Lowe, A.; Paquola, C.; Jefferies, E.; Hartley, T.; Bernasconi, A.; Bernasconi, N.; Smallwood, J.; Bohbot, V.; Caciagli, L.; Bernhardt, B.
10.1101/2020.10.14.338947 — neuroscience — Posted on 2020-10-15
2388 Synergistic anticancer effect of plasma-activated infusion and salinomycin by targeting autophagy and mitochondrial morphology
Andou, T.; Suzuki-Karasaki, M.; Suzuki-Karasaki, M.; Ichikawa, J.; Ochiai, T.; Yoshida, Y.; Haro, H.; Suzuki-Karasaki, Y.
10.1101/2020.10.14.340208 — cancer biology — Posted on 2020-10-15
2390 Full-length transcript sequencing of human and mouse identifies widespread isoform diversity and alternative splicing in the cerebral cortex
Jeffries, A. R.; Leung, S. K.; Castanho, I.; Moore, K.; Davies, J.; Dempster, E.; Bray, N. J.; O'Neill, P.; Tseng, E. J.; Ahmed, Z.; Collier, D.; Prabhakar, S.; Scalkwyk, L.; Gandal, M.; Hannon, E.; Mill, J.
10.1101/2020.10.14.339200 — genomics — Posted on 2020-10-15
2391 Collective nuclear behavior shapes bilateral nuclear symmetry for subsequent left-right asymmetric morphogenesis in Drosophila
Shin, D.; Nakamura, M.; Morishita, Y.; Eiraku, M.; Yamakawa, T. Y.; Sasamura, T. S.; Akiyama, M. A.; Inaki, M.; Matsuno, K. M.
10.1101/2020.10.15.340521 — cell biology — Posted on 2020-10-15
2393 Nucleolin is expressed in human fetal brain development and reactivated in human glial brain tumors regulating angiogenesis and vascular metabolism
Schwab, M.; De Trizio, I.; Shiu, J.-Y.; Ghobrial, M.; Surucu, O.; Girolamo, F.; Errede, M.; Yilmaz, M.; Haybaeck, J.; Moiraghi, A.; Monnier, P.; Lawler, S.; Greenfield, J. P.; Radovanovic, I.; Frei, K.; Schlapbach, R.; Vogel, V.; Virgintino, D.; De Bock, K.; Walchli, T.
10.1101/2020.10.14.337824 — neuroscience — Posted on 2020-10-15
2396 Large scale metagenome assembly reveals novel animal-associated microbial genomes, biosynthetic gene clusters, and other genetic diversity
Youngblut, N. D.; de la Cuesta-Zuluaga, J.; Reischer, G. H.; Dauser, S.; Schuster, N.; Walzer, C.; Stalder, G.; Farnleitner, A.; Ley, R. E.
10.1101/2020.06.05.135962 — microbiology — Posted on 2020-10-15
2398 An interactive meta-analysis of MRI biomarkers of myelin
Mancini, M.; Karakuzu, A.; Cohen-Adad, J.; Cercignani, M.; Nichols, T.; Stikov, N.
10.1101/2020.07.13.200972 — neuroscience — Posted on 2020-10-15
2402 Promiscuous esterases counterintuitively are less flexible than specific ones
Nutschel, C.; Coscolin, C.; Mulnaes, D.; David, B.; Ferrer, M.; Jaeger, K.-E.; Gohlke, H.
10.1101/2020.06.02.129015 — biophysics — Posted on 2020-10-15
2409 Pseudomonas aeruginosa secreted protein PA3611 promotes bronchial epithelial cells epithelial-mesenchymal transition through TGF-β1 inducing p38/miRNA/NF-κB pathway
Shu, L.; Chen, S.; Chen, X.; Lin, S.; Du, X.; Deng, K.; Wei, J.; Cao, Y.; Yan, J.; Shen, Z.; Feng, G.; Sixia Chen, Xiaolin Chen, Shaoqing Lin, Xingran Du, Kaili Deng, Jing Wei, Yang Cao, Jiaxin Yan, Ziya,
10.1101/2020.10.14.339044 — microbiology — Posted on 2020-10-14
2410 Heterozygous deletion of SYNGAP enzymatic domains in rats causes selective learning, social and seizure phenotypes
Katsanevaki, D.; Till, S. M.; Buller-Peralta, I.; Watson, T. C.; Nawaz, M. S.; Arkell, D.; Tiwari, S.; Kapgal, V.; Biswal, S.; Smith, J. A.; Anstey, N. J.; Mizen, L.; Perentos, N.; Jones, M. W.; Cousin, M. A.; Chattarji, S.; Gonzalez-Sulser, A.; Hardt, O.; Wood, E. R.; Kind, P. C.
10.1101/2020.10.14.339192 — neuroscience — Posted on 2020-10-14
2411 Selective connectivity limits functional binocularity in the retinogeniculate pathway of the mouse
Bauer, J.; Weiler, S.; Fernholz, M.; Laubender, D.; Scheuss, V.; Hübener, M.; Bonhoeffer, T.; Rose, T.
10.1101/2020.10.14.339747 — neuroscience — Posted on 2020-10-14
2413 How do neuroglial cells respond to ultrasound induced cavitation?
Wrede, A. H.; Luo, J.; Montazami, R.; Kanthasamy, A.; Hashemi, N. N.
10.1101/2020.10.14.339002 — bioengineering — Posted on 2020-10-14
2415 Ancient DNA from Guam and the Peopling of the Pacific
Pugach, I.; Hubner, A.; Hung, H.-C.; Meyer, M.; Carson, M. T.; Stoneking, M.
10.1101/2020.10.14.339135 — evolutionary biology — Posted on 2020-10-14
2417 Rapidemic, a versatile and label-free DNAzyme-based platform for visual nucleic acid detection
van den Brink, M.; Tandar, S. T.; van den Akker, T. A. P.; Jovikj, S.; Defourt, V.; Langelaar, T. G. B.; Delzenne, T. O.; van Strien, K.; Schonk, A. W.; Beers, A. J. A. M.; Golov, E.; Chong, L. J.; Özer Bergman, G.; Meijdam, J. J. W. D.; Crooijmans, M. E.; Claessen, D.; de Winde, J. H.
10.1101/2020.10.14.337808 — molecular biology — Posted on 2020-10-14
2418 Convergence of a common solution to broad ebolavirus neutralization by glycan cap directed human antibodies
Murin, C. D.; Gilchuk, P.; Ilinykh, P.; Huang, K.; Kuzmina, N.; Shen, X.; Brunh, J. F.; Brunh, A. L.; Davidson, E.; Doranz, B.; Williamson, L. E.; Copps, J.; Alkutkar, T.; Flyak, A. I.; Bukreyev, A.; Crowe, J. E.; Ward, A. B.
10.1101/2020.10.14.340026 — immunology — Posted on 2020-10-14
2420 Characterisation of growth plate dynamics in murine models of osteoarthritis
Samvelyan, H. J.; Madi, K.; Tornqvist, A. E.; Javaheri, B.; Staines, K. A.
10.1101/2020.10.14.339119 — physiology — Posted on 2020-10-14
2421 Pancreatic β-cell specific loss of E2f1 impairs insulin secretion and β-cell identity through the epigenetic repression of non β-cell programs
Oger, F.; Bourouh, C.; Gromada, X.; Moreno, M.; Carney, C.; Courty, E.; Rabhi, N.; Durand, E.; Amanzougarene, S.; Berberian, L.; Derhourhi, M.; Rolland, L.; Hannou, S. A.; Denechaud, P.-D.; Benfodda, Z.; Meffre, P.; Fajas, L.; Kerr-Conte, J.; Pattou, F.; Froguel, P.; Bonnefond, A.; ANNICOTTE, J.-S.
10.1101/2020.10.14.339929 — physiology — Posted on 2020-10-14
2422 Alisertib exerts KRAS allele specific anticancer effects in colorectal cancer
Ren, B.; Gao, Z.; Zheng, K.; Yang, Y.; Su, P.; Luo, Q.; Feng, J.; Luo, Z.; Geng, Y.; Ju, Y.; Huang, Z.
10.1101/2020.10.14.340125 — cancer biology — Posted on 2020-10-14
2425 Automated Segmentation of Fractured Distal Radii by 3D Geodesic Active Contouring of in vivo HR-pQCT Images
Ohs, N.; Tourolle, D. C.; Atkins, P. R.; Collins, C. J.; Schroeder, B.; Blauth, M.; Christen, P.; Müller, R.
10.1101/2020.10.14.339739 — bioengineering — Posted on 2020-10-14
2426 Cohesin residency determines chromatin loop patterns
Costantino, L.; Hsieh, T.-H. S.; Lamothe, R.; Darzacq, X. D.; Koshland, D. E.
10.1101/2020.06.11.146902 — genomics — Posted on 2020-10-14
2428 Temporal stability of human sperm mosaic mutations results in life-long threat of transmission to offspring
Yang, X.; Breuss, M. W.; Xu, X.; Antaki, D.; James, K. N.; Stanley, V.; Ball, L. L.; George, R. D.; Wirth, S. A.; Cao, B.; Nguyen, A.; McEvoy-Venneri, J.; Chai, G.; Nahas, S.; Van Der Kraan, L.; Ding, Y.; Sebat, J.; Gleeson, J. G.
10.1101/2020.10.14.339796 — genomics — Posted on 2020-10-14
2429 Ecological specialisation and evolutionary reticulation in extant Hyaenidae
Westbury, M. V.; Le Duc, D.; Duchene, D. A.; Krishnan, A.; Prost, S.; Rutschmann, S.; Grau, J. H.; Weyrich, A.; Noren, K.; Werdelin, L.; Dalerum, F.; Schoeneberg, T.; Hofreiter, M.
10.1101/2020.10.14.338871 — evolutionary biology — Posted on 2020-10-14
2435 Toxoplasma gondii GRA28 is required for specific induction of the regulatory chemokine CCL22 in human and mouse cells.
Rudzki, E. N.; Ander, S. E.; Coombs, R. S.; Alrubaye, H. S.; Cabo, L. F.; Blank, M. L.; Gutierrez-Melo, N.; Dubey, J.; Coyne, C. B.; Boyle, J. P.
10.1101/2020.10.14.335802 — microbiology — Posted on 2020-10-14
2437 Influence of sensory modality and control dynamics on human path integration
Stavropoulos, A.; Lakshminarasimhan, K. J.; Laurens, J.; Pitkow, X.; Angelaki, D.
10.1101/2020.09.21.307256 — neuroscience — Posted on 2020-10-14
2440 Correlation and co-localization of QTL for stomatal density and canopy temperature under drought stress in Setaria
Prakash, P. T.; Banan, D.; Paul, R.; Feldman, M. J.; Xie, D.; Freyfogle, L.; Baxter, I.; Leakey, A. D. B.
10.1101/2020.10.14.339580 — plant biology — Posted on 2020-10-14
2442 HDAC3 regulates senescence and lineage-specific transcriptional programs in non-small cell lung cancer
Eichner, L. J.; Curtis, S. D.; Brun, S. N.; Baumgart, J. T.; Ross, D. S.; Rymoff, T. J.; Shaw, R. J.
10.1101/2020.10.14.338590 — cancer biology — Posted on 2020-10-14
2444 CaBagE: a Cas9-based Background Elimination strategy for targeted, long-read DNA sequencing
Wallace, A.; Sasani, T.; Swanier, J.; Gates, B.; Greenland, J.; Pedersen, B.; Varley, K.; Quinlan, A. R.
10.1101/2020.10.13.337253 — genetics — Posted on 2020-10-14
2449 Identification of a recently dominate sublineage in Salmonella 4,,12:i:- sequence type 34 isolated from food animals in Japan
Arai, N.; Sekizuka, T.; Tamamura-Andoh, Y.; Barco, L.; Hinenoya, A.; Yamasaki, S.; Iwata, T.; Watanabe-Yanai, A.; Kuroda, M.; Akiba, M.; Kusumoto, M.
10.1101/2020.10.14.338830 — microbiology — Posted on 2020-10-14
2450 Use of convalescent serum reduces severity of COVID-19 in nonhuman primates
cross, r.; Prasad, A. N.; Borisevich, V.; Woolsey, C.; Agans, K. N.; Deer, D. J.; Dobias, N. S.; Geisbert, J. B.; Fenton, K. A.; Geisbert, T. W.
10.1101/2020.10.14.340091 — microbiology — Posted on 2020-10-14
2451 IL-13 deficiency exacerbates lung damage and impairs epithelial-derived type 2 molecules during nematode infection
Chenery, A. L.; Rosini, S.; Parkinson, J.; Herrera, J. A.; Lawless, C.; Chan, B. H.; Loke, P. A.; MacDonald, A. S.; Kadler, K.; Sutherland, T. E.; Allen, J. E.
10.1101/2020.10.14.337949 — immunology — Posted on 2020-10-14
2453 Multiscale and multimodal reconstruction of cortical structure and function
Turner, N. L.; Macrina, T.; Bae, J. A.; Yang, R.; Wilson, A. M.; Schneider-Mizell, C.; Lee, K.; Lu, R.; Wu, J.; Bodor, A. L.; Bleckert, A. A.; Brittain, D.; Froudarakis, E.; Dorkenwald, S.; Collman, F.; Kemnitz, N.; Ih, D.; Silversmith, W. M.; Zung, J.; Zlateski, A.; Tartavull, I.; Yu, S.-c.; Popovych, S.; Mu, S.; Wong, W.; Jordan, C. S.; Castro, M.; Buchanan, J.; Bumbarger, D. J.; Takeno, M.; Torres, R.; Mahalingam, G.; Elabbady, L.; Li, Y.; Cobos, E.; Zhou, P.; Suckow, S.; Becker, L.; Paninski, L.; Polleux, F.; Reimer, J.; Tolias, A. S.; Reid, R. C.; Macarico da Costa, N.; Seung, H. S.
10.1101/2020.10.14.338681 — neuroscience — Posted on 2020-10-14
2460 Immunomagnetic Sequential Ultrafiltration (iSUF) Platform for Enrichment and Purification of Extracellular Vesicles from Biofluids
Zhang, J.; Nguyen, L. T.; Hickey, R.; Walters, N.; Wang, X.; Kwak, K.; Lee, L. J.; Palmer, A. F.; Reategui, E.
10.1101/2020.05.13.089573 — bioengineering — Posted on 2020-10-14
2464 Climate explains geographic and temporal variation in mosquito-borne disease dynamics on two continents
Caldwell, J. M.; LaBeaud, A. D.; Lambin, E. F.; Stewart-Ibarra, A. M.; Ndenga, B. A.; Mutuku, F. M.; Krystosik, A. R.; Ayala, E. B.; Anyamba, A.; Borbor-Cordova, M. J.; Damoah, R.; Grossi-Soyster, E. N.; Heras Heras, F.; Ngugi, H. N.; Ryan, S. J.; Shah, M. M.; Sippy, R.; Mordecai, E. A.
10.1101/2020.02.07.938720 — ecology — Posted on 2020-10-14
2465 Transcription Termination and Antitermination of Bacterial CRISPR Arrays
Stringer, A. M.; Baniulyte, G.; Lasek-Nesselquist, E.; Seed, K.; Wade, J. T.
10.1101/405316 — microbiology — Posted on 2020-10-14
2466 Early Stem Cell Aging in the Mature Brain
Ibrayeva, A.; Bay, M.; Pu, E.; Jorg, D.; Peng, L.; Jun, H.; Zhang, N.; Aaron, D.; Lin, C.; Resler, G.; Hidalgo, A.; Jang, M.-H.; Simons, B. D.; Bonaguidi, M. A.
10.1101/654608 — neuroscience — Posted on 2020-10-14
2469 Asymmetrical pegs in square holes? Functional and phylogenetic determinants of plant community assembly in temperate forest understories
Beck, J. J.; Li, D.; Johnson, S. E.; Rogers, D.; Cameron, K. M.; Sytsma, K. J.; Givnish, T. J.; Waller, D. M.
10.1101/2020.10.14.312512 — ecology — Posted on 2020-10-14
2470 Direct cleavage of human NLRP1 by enteroviral 3C protease triggers inflammasome activation in airway epithelium
Robinson, K.; Teo, D. E. T.; Tan, K. S.; Toh, G. A.; Ong, H. H.; Lim, C. K.; Lay, K.; Au, B. V.; Lew, T. S.; Chu, J. J. H.; Chow, V. T. K.; Wang, D. Y.; Zhong, F. L.; Reversade, B.
10.1101/2020.10.14.325076 — immunology — Posted on 2020-10-14
2471 3D test sample for the calibration and quality control of super-resolution and confocal microscopes
van der Wee, E. B.; Fokkema, J.; Kennedy, C. L.; del Pozo, M.; de Winter, M.; Speets, P. N. A. S.; Gerritsen, H. C.; van Blaaderen, A.
10.1101/2020.10.14.336032 — biophysics — Posted on 2020-10-14
2473 The viral protein NSP1 acts as a ribosome gatekeeper for shutting down host translation and fostering SARS-CoV-2 translation
Tidu, A.; Janvier, A.; Schaeffer, L.; Sosnowski, P.; Kuhn, L.; Hammann, P.; Westhof, E.; Eriani, G.; Martin, F.
10.1101/2020.10.14.339515 — molecular biology — Posted on 2020-10-14
2474 Immunogenicity of novel mRNA COVID-19 vaccine MRT5500 in mice and non-human primates
Kalnin, K. V.; Plitnik, T.; Kishko, M.; Zhang, J.; Zhang, D.; Beauvais, A.; Anosova, N. G.; Tibbitts, T.; DiNapoli, J. M.; Huang, P.-W. D.; Huleatt, J.; Vincent, D.; Fries, K.; Karve, S.; Goldman, R.; Gopani, H.; Dias, A.; Tran, K.; Zacharia, M.; Gu, X.; Boeglin, L.; Chivukula, S.; Swearingen, R.; Landolfi, V.; Fu, T.-M.; DeRosa, F.; Casimiro, D.
10.1101/2020.10.14.337535 — immunology — Posted on 2020-10-14
2476 Diazepam attenuates the effects of cocaine on locomotion, 50-kHz ultrasonic vocalizations and phasic dopamine release in the nucleus accumbens of rats
Sanchez Luna, W. N.; Pochapski, J. A.; Jessen, L. F.; Ellenberg, M.; Robinson, D. L.; Schwarting, R. K.; Andreatini, R.; da Cunha, C.
10.1101/2020.10.13.338343 — pharmacology and toxicology — Posted on 2020-10-14
2477 Connexin 43 confers chemoresistance through activating PI3K
Pridham, K.; Shah, F.; Sheng, K.; Guo, S.; Liu, M.; Kanabur, P.; Lamouille, S.; Lewis, G.; Morales, M.; Jourdan, J.; Grek, C.; Ghatnekar, G.; Varghese, R.; Kelly, D.; Gourdie, R. G.; Sheng, Z.
10.1101/2020.10.14.339275 — cancer biology — Posted on 2020-10-14
2480 Structural stability of SARS-CoV-2 degrades with temperature
Sharma, A.; Preece, B.; Swann, H.; Fan, X.; McKenney, R. J.; Ori-McKenney, K. M.; Saffarian, S.; Vershinin, M.
10.1101/2020.10.12.336818 — biophysics — Posted on 2020-10-14
2483 MaveRegistry: a collaboration platform for multiplexed assays of variant effect
Kuang, D.; Weile, J.; Kishore, N.; Rubin, A. F.; Fields, S.; Fowler, D. M.; Roth, F. P.
10.1101/2020.10.14.339499 — bioinformatics — Posted on 2020-10-14
2484 COVID19: Exploring uncommon epitopes for a stable immune response through MHC1 binding
Abitogun, F. M.; Srivastava, R.; Sharma, S.; Komarysta, V.; Akurut, E.; Munir, N.; Macalalad, L.; Ojo-Rowland, O.; Owolabi, O.; Giwa, A.; Debnath, S.
10.1101/2020.10.14.339689 — bioinformatics — Posted on 2020-10-14
2489 Effects of NT5C2 germline variants on 6-mecaptopurine metabolism in children with acute lymphoblastic leukemia
Jiang, C.; Yang, W.; Moriyama, T.; Liu, C.; Smith, C.; Yang, W.; Qian, M.; Li, Z.; Tulstrup, M.; Schmiegelow, K.; Crews, K. R.; Zhang, H.; Pui, C.-H.; Evans, W. E.; Relling, M.; Bhatia, S.; Yang, J. J.
10.1101/2020.10.13.338384 — genetics — Posted on 2020-10-14
2492 High-resolution architecture of human epiphysis formation
Sun, H.; Wen, Y.; Wu, W.; Qin, T.; An, C.; Fan, C.; Chen, Y.; Ji, J.; Chew, T. G.; Chen, J.; Ouyang, H.
10.1101/2020.10.13.337733 — developmental biology — Posted on 2020-10-14
2493 The ubiquitylome of developing cortical neurons
Menon, S.; Goldfarb, D.; Cousins, E. M.; Major, M. B.; Gupton, S. L.
10.1101/2020.10.13.337782 — cell biology — Posted on 2020-10-14
2494 Cell size homeostasis is maintained by a circuitry involving a CDK4-determined target size that programs the cell size-dependent activation of p38
Tan, C.; Ginzberg, M. B.; Webster, R.; Iyengar, S.; Concannon, J.; Wang, Y.; Auld, D. S.; Jenkins, J. L.; Rost, H.; Hilfinger, A.; Derry, B.; Patel, N.; Kafri, R.
10.1101/2020.10.14.339556 — cell biology — Posted on 2020-10-14
2496 A CRISPR interference platform for selective downregulation of gene expression in Borrelia burgdorferi
Takacs, C. N.; Scott, M.; Chang, Y.; Kloos, Z. A.; Irnov, I.; Rosa, P. A.; Liu, J.; Jacobs-Wagner, C.
10.1101/2020.10.12.335471 — microbiology — Posted on 2020-10-14
2498 Co-infection of influenza A virus enhances SARS-CoV-2 infectivity
Bai, L.; Zhao, Y.; Dong, J.; Liang, S.; Guo, M.; Liu, X.; Wang, X.; Huang, Z.; Sun, X.; Zhang, Z.; Dong, L.; Liu, Q.; Zheng, Y.; Niu, D.; Xiang, M.; Song, K.; Ye, J.; Zheng, W.; Tang, Z.; Tang, M.; Zhou, Y.; Shen, C.; Dai, M.; Zhou, L.; Chen, Y.; Yan, H.; Lan, K.; Xu, K.
10.1101/2020.10.14.335893 — microbiology — Posted on 2020-10-14
2499 In vivo evaluation of the antiviral effect of ClO2 in chicken embryos inoculated with avian infectious bronchitis coronavirus
Zambrano-Estrada, X.; Dominguez-Sanchez, C. A.; Banuet-Martinez, M.; Guerrero-de la Rosa, F.; Garcia-Gasca, T.; Acevedo-Whitehouse, K.
10.1101/2020.10.13.336768 — microbiology — Posted on 2020-10-14
2500 Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters
Piepenbrink, M. S.; Park, J.-G.; Oladunni, F.; Deshpande, A.; Basu, M.; Sarkar, S.; Loos, A.; Woo, J.; Lovalenti, P.; Sloan, D.; Ye, C.; Chiem, K.; Erdmann, N. B.; Goepfert, P. A.; Truong, V. L.; Walter, M. R.; Martinez-Sobrido, L.; Kobie, J. J.
10.1101/2020.10.14.339150 — immunology — Posted on 2020-10-14
2501 Rapid Development of Neutralizing and Diagnostic SARS-COV-2 Mouse Monoclonal Antibodies
Chapman, A. P.; Tang, X.; Lee, J. R.; Chida, A.; Mercer, K.; Wharton, R. E.; Kainulainen, M. H.; Harcourt, J. L.; Martines, R. B.; Schroeder, M.; Zhao, L.; Bryksin, A.; Zhou, B.; Bergeron, E.; Bollweg, B. C.; Tamin, A.; Thornburg, N.; Wentworth, D. E.; Petway, D.; Bagarozzi, D.; Finn, M. G.; Goldstein, J. M.
10.1101/2020.10.13.338095 — immunology — Posted on 2020-10-14
2502 Assessing cerebellar-cortical connectivity using concurrent TMS-EEG: A Feasibility Study
Fernandez, L.; Biabani, M.; Opie, G. M.; Hill, A. T.; Barham, M. P.; Teo, W.-P.; Byrne, L. K.; Do, M.; Rogasch, N. C.; Enticott, P. G.
10.1101/2020.10.13.338350 — neuroscience — Posted on 2020-10-14
2503 Neural correlates of interpersonal space permeability and flexibility in autism spectrum disorder
Massaccesi, C.; Groessing, A.; Rosenberger, L. A.; Hartmann, H.; Candini, M.; di Pellegrino, G.; Frassinetti, F.; Silani, G.
10.1101/2020.10.14.339291 — neuroscience — Posted on 2020-10-14
2507 Oncometabolism Drives Autophagy Activation in Skeletal Muscle
Karlstaedt, A.; Vitrac, H.; Salazar, R. L.; Gould, B. D.; Soedkamp, D.; Spivia, W.; Raedschelders, K.; Dinh, A. Q.; Guzman, A.; Tan, L.; Azinas, S.; Taylor, D. J. R.; Schiffer, W.; McNavish, D.; Burks, H. B.; Gottlieb, R. A.; Lorenzi, P. L.; Hanson, B.; Van Eyk, J. E.; Taegtmeyer, H.
10.1101/2020.10.13.338202 — systems biology — Posted on 2020-10-14
2515 Comparison of Extracellular Vesicle Isolation Methods from Human Biofluids using Single Molecule Arrays
Ter-Ovanesyan, D.; Norman, M.; Trieu, W.; Lee, J.; Lazarovits, R.; Church, G.; Walt, D. R.
10.1101/2020.10.13.337881 — biochemistry — Posted on 2020-10-14
2517 Modelling selection response in plant breeding programs using crop models as mechanistic gene-to-phenotype (CGM-G2P) multi-trait link functions
Cooper, M.; Powell, O.; Voss-Fels, K. P.; Messina, C.; Gho, C.; Podlich, D.; Technow, F.; Chapman, S.; Beveridge, C. A.; Ortiz-Barrientos, D.; Hammer, G. L.
10.1101/2020.10.13.338301 — genetics — Posted on 2020-10-14
2519 The Polycomb group protein MEDEA controls cell proliferation and embryonic patterning in Arabidopsis
Simonini, S.; Bemer, M.; Bencivenga, S.; Gagliardini, V.; Pires, N.; Desvoyes, B.; van der Graaff, E.; Gutierrez, C.; Grossniklaus, U.
10.1101/2020.10.13.338707 — developmental biology — Posted on 2020-10-14
2522 Education and income show heterogeneous relationships to lifespan brain and cognitive differences across European and US cohorts
Walhovd, K. B.; Fjell, A.; Wang, Y.; Amlien, I. K.; Mowinckel, A. M.; Lindenberger, U.; Duezel, S.; Bartres-Faz, D.; Ebmeier, K.; Drevon, C. A.; Barre, W.; Ghisletta, P.; Johansen, L. B.; Kievit, R. A.; Henson, R. N.; Madsen, K. S.; Nyberg, L.; Harris, J. R.; Sole-Padulles, C.; Pudas, S.; Sorensen, O.; Westerhausen, R.; Zsoldos, E.; Nawijn, L.; Lyngstad, T. H.; Suri, S.; Penninx, B.; Rogeberg, O. J.; Brandmaier, A.
10.1101/2020.10.12.335687 — neuroscience — Posted on 2020-10-14
2523 The effect of functionally-guided-connectivity-based rTMS on amygdala activation.
Beynel, L.; Campbell, E.; Naclerio, M.; Galla, J. T.; Ghosal, A.; Michael, A. M.; Kimbrel, N. A.; Davis, S. W.; Appelbaum, L. G.
10.1101/2020.10.13.338483 — neuroscience — Posted on 2020-10-14
2525 Sex, androgens and regulation of pulmonary AR, TMPRSS2 and ACE2
Baratchian, M.; McManus, J.; Berk, M.; Nakamura, F.; Mukhopadhyay, S.; Xu, W.; Erzurum, S.; Mukhopadhyay, S.; Drazba, J.; Peterson, J.; Klein, E. A.; Gaston, B.; Sharifi, N.
10.1101/2020.04.21.051201 — physiology — Posted on 2020-10-14
2530 A White Matter Atlas and Common Connectivity Space Facilitate the Pig as a Translational Model in Neuroscience
Benn, R. A.; Mars, R. B.; Xu, T.; Rodriguez-Esparragoza, L.; Montesinos, P.; Manzano-Patron, J. P.; Lopez-Martin, G.; Fuster, V.; Gonzalez-Sanchez, J.; Duff, E. P.; Ibanez, B.
10.1101/2020.10.13.337436 — neuroscience — Posted on 2020-10-14
2531 Tau pathology spreads between anatomically-connected regions of the brain and is modulated by a LRRK2 mutation
Henderson, M.; Cornblath, E. J.; Li, H. L.; Changolkar, L.; Zhang, B.; Brown, H. J.; Gathagan, R. J.; Olufemi, M. F.; Bassett, D. S.; Trojanowski, J. Q.; Lee, V. M. Y.
10.1101/2020.10.13.337857 — neuroscience — Posted on 2020-10-14
2533 Auxin guides germ cell specification in Arabidopsis anthers
Zheng, Y.; Wang, D.; Ye, S.; Chen, W.; Li, G.; Xu, Z.; Bai, S.; Zhao, F.
10.1101/2020.10.13.337634 — plant biology — Posted on 2020-10-14
2535 Longitudinal survey reveals delayed effects of forager gene expression on stingless bee colony health
Caesar, L.; Lopes, A. M. C.; Radaeski, J. N.; Bauermann, S. G.; Konzen, E. R.; Pombert, J.-F.; Sattler, A.; Blochtein, B.; de Carvalho, A. T.; Haag, K. L.
10.1101/2020.10.13.337527 — pathology — Posted on 2020-10-14
2542 Stalling chromophore maturation of the fluorescent protein Venus reveals the molecular basis of the final oxidation step
Auhim, H.; Grigorenko, B.; Harris, T.; Polyakov, I.; Berry, C.; dos Passos Gomes, G.; Alabugin, I.; Rizkallah, P.; Nemukhin, A. V.; Jones, D.
10.1101/2020.10.13.337386 — biochemistry — Posted on 2020-10-14
2543 RNA regulates Glycolysis and Embryonic Stem Cell Differentiation via Enolase 1
Huppertz, I.; Perez-Perri, J. I.; Mantas, P.; Sekaran, T.; Schwarzl, T.; Dimitrova-Paternoga, L.; Hennig, J.; Neveu, P. A.; Hentze, M. W.
10.1101/2020.10.14.337444 — molecular biology — Posted on 2020-10-14
2544 In Vivo Brain Glutathione is Higher in Older Age and Correlates with Mobility
Hupfeld, K. E.; Hyatt, H. W.; Alvarez Jerez, P.; Mikkelsen, M.; Hass, C. J.; Edden, R. A. E.; Seidler, R. D.; Porges, E. C.
10.1101/2020.10.14.339507 — neuroscience — Posted on 2020-10-14
2545 DNA Methyltransferase Inhibitors with Novel Chemical Scaffolds
Juarez-Mercado, K. E.; Prieto-Martinez, F. D.; Sanchez-Cruz, N.; Pena-Castillo, A.; Prada-Gracia, D.; Medina-Franco, J. L.
10.1101/2020.10.13.337709 — systems biology — Posted on 2020-10-14
2546 Carbon dots deposition in adult bones reveal areas of growth, injury and regeneration
DuMez, R.; Miyanji, E.; Corado-Santiago, L.; Barrameda, B.; Zhou, Y.; Hettiarachchi, S. D.; Leblanc, R.; Skromne, I.
10.1101/2020.10.13.338426 — pharmacology and toxicology — Posted on 2020-10-14
2547 Large-scale transcriptomics to dissect two years of the life of a fungal phytopathogen interacting with its host plant
Gay, E. J.; Soyer, J. L.; Lapalu, N.; Linglin, J.; Fudal, I.; Da Silva, C.; Wincker, P.; Aury, J.-M.; Cruaud, C.; Levrel, A.; Lemoine, J.; Delourme, R.; Rouxel, T.; Balesdent, M.-H.
10.1101/2020.10.13.331520 — pathology — Posted on 2020-10-14
2549 PIP2 promotes conformation-specific dimerization of the EphA2 membrane region
Stefanski, K. M.; Russell, C. M.; Westerfield, J. M.; Lamichhane, R.; Barrera, F. N.
10.1101/2020.10.14.338293 — biophysics — Posted on 2020-10-14
2553 Novel epigenetic clock for fetal brain development predicts fetal epigenetic age for iPSCs and iPSC-derived neurons.
Steg, L. C.; Shireby, G. L.; Imm, J.; Davies, J. P.; Flynn, R.; Namboori, S. C.; Bhinge, A.; Jeffries, A. R.; Burrage, J.; Neilson, G. W. A.; Walker, E. M.; Perfect, L. W.; Price, J.; Bray, N. J.; Cope, E. L.; Jones, K. M.; Allen, N. D.; Pishva, E.; Mill, J.; Lunnon, K.; Hannon, E.
10.1101/2020.10.14.339093 — neuroscience — Posted on 2020-10-14
2554 Does dopamine synthesis capacity predict individual variation in curiosity?
van Lieshout, L. L. F.; van den Bosch, R.; Hofmans, L.; de Lange, F. P.; Cools, R.
10.1101/2020.10.13.337477 — neuroscience — Posted on 2020-10-14
2557 Distinct progenitor behavior underlying neocortical gliogenesis related to tumorigenesis
Shen, Z.; Lin, Y.; Yang, J.; Jörg, D. J.; Peng, Y.; Zhang, X.; Xu, Y.; Hernandez, L.; Ma, J.; Simons, B. D.; Shi, S.-H.
10.1101/2020.10.13.338459 — developmental biology — Posted on 2020-10-14
2559 Low doses of radiation increase the immunosuppressive profile of lung macrophages during viral infection and pneumonia
Meziani, L.; Robert, C.; Classe, M.; Da Costa, B.; Mondini, M.; Clemenson, C.; Mordant, P.; Ammari, S.; Le Goffic, R.; Deutsch, E.
10.1101/2020.05.11.077651 — immunology — Posted on 2020-10-14
2562 The inhibition of LSD1 via sequestration contributes to tau-mediated neurodegeneration
Engstrom, A. K.; Walker, A. C.; Moudgal, R. A.; Myrick, D. A.; Kyle, S. M.; Rowley, J.; Katz, D. J.
10.1101/745133 — neuroscience — Posted on 2020-10-14
2563 A molecular mechanism by which amyloid-β induces transcriptional inactivation of CREB in Alzheimer's Disease
Grochowska, K. M.; Kaushik, R.; Gomes, G. M.; Raman, R.; Baer, J.; Bayraktar, G.; Samer, S.; Reyes-Resina, I.; Spilker, C.; Woo, M. S.; Bikbaev, A.; Morawski, M.; Friese, M. A.; Rossner, S.; Navarro Brugal, G.; Karpova, A.; Kreutz, M. R.
10.1101/2020.01.08.898304 — neuroscience — Posted on 2020-10-14
2567 Neuronal NOX4 knockdown alleviates pathological tau-related alterations in a humanized mouse model of tauopathy
Luengo, E.; Trigo-Alonso, P.; Fernandez-Mendivil, C.; Nunez, A.; del Campo, M.; Porrero, C.; Garcia-Magro, N.; Negredo, P.; Sanchez, C.; Bernal, J. A.; Rabano, A.; Hoozemans, J.; Casas, A. I.; Schmidt, H. H.; Cuervo, A. M.; Lopez, M. G.
10.1101/2020.10.14.338954 — neuroscience — Posted on 2020-10-14
2572 scATAC-Seq reveals epigenetic heterogeneity associated with an EMT-like process in male germline stem cells and its regulation by G9a
Liao, J.; Suen, H. C.; Luk, A. C. S.; Lee, A. W. T.; Ng, J. K. W.; Chan, T. H. T.; Cheung, M. Y.; Chan, D. Y. L.; Li, T. C.; Qi, H.; Chan, W.-Y.; Hobbs, R. M.; Lee, T. L.
10.1101/2020.10.12.336834 — cell biology — Posted on 2020-10-14
2575 Capsular polysaccharide switching in Streptococcus suis modulates host cell interactions and virulence
Okura, M.; Auger, J.-P.; Shibahara, T.; Goyette-Desjardins, G.; Van Calsteren, M.-R.; Maruyama, F.; Kawai, M.; Osaki, M.; Segura, M.; Gottschalk, M.; Takamatsu, D.
10.1101/2020.10.12.336958 — microbiology — Posted on 2020-10-14
2576 Morphologically constrained modeling of spinous inhibition in the somato-sensory cortex
Gemin, O.; Serna, P.; Assendorp, N.; Fossati, M.; Rostaing, P.; Triller, A.; Charrier, C.
10.1101/2020.08.06.230722 — neuroscience — Posted on 2020-10-14
2577 The PopN gate-keeper complex acts on the ATPase PscN to regulate the T3SS secretion switch from early to middle substrates in Pseudomonas aeruginosa
Ngo, T. D.; Perdu, C.; Jneid, B.; Ragno, M.; Novion Ducassou, J.; Kraut, A.; Coute, Y.; Stopford, C.; Attree, I.; Rietsch, A.; Faudry, E.
10.1101/2020.07.28.224923 — biochemistry — Posted on 2020-10-14
2580 Multiscale and multimodal reconstruction of cortical structure and function
Turner, N. L.; Macrina, T.; Bae, J. A.; Yang, R.; Wilson, A. M.; Schneider-Mizell, C.; Lee, K.; Lu, R.; Wu, J.; Bodor, A. L.; Bleckert, A. A.; Brittain, D.; Froudarakis, E.; Dorkenwald, S.; Collman, F.; Kemnitz, N.; Ih, D.; Silversmith, W. M.; Zung, J.; Zlateski, A.; Tartavull, I.; Yu, S.-c.; Popovych, S.; Mu, S.; Wong, W.; Jordan, C. S.; Castro, M.; Buchanan, J.; Bumbarger, D. J.; Takeno, M.; Torres, R.; Mahalingam, G.; Elabbady, L.; Li, Y.; Cobos, E.; Zhou, P.; Suckow, S.; Becker, L.; Paninski, L.; Polleux, F.; Reimer, J.; Tolias, A. S.; Reid, R. C.; Macarico da Costa, N.; Seung, H. S.
10.1101/2020.10.14.338681 — neuroscience — Posted on 2020-10-14
2581 An online headphone screening test based on dichotic pitch
Milne, A. E.; Bianco, R.; Poole, K. C.; Zhao, S.; Oxenham, A. J.; Billig, A. J.; Chait, M.
10.1101/2020.07.21.214395 — neuroscience — Posted on 2020-10-14
2583 Importin α2 association with chromatin: Direct DNA binding via a novel DNA binding domain
Jibiki, K.; Kodama, T.; Suenaga, A.; Kawase, Y.; Shibazaki, N.; Nomoto, S.; Nagasawa, S.; Nagashima, M.; Shimodan, S.; Kikuchi, R.; Okayasu, M.; Takashita, R.; Mehmood, R.; Saitoh, N.; Yoneda, Y.; Akagi, K.-i.; Yasuhara, N.
10.1101/2020.05.04.075580 — molecular biology — Posted on 2020-10-14
2586 Determining insulin sensitivity from glucose tolerance tests in Iberian and Landrace pigs
Rodriguez-Lopez, J. M.; Lachica, M.; Gonzalez-Valero, L.; Fernandez-Figares, I.
10.1101/2019.12.20.884056 — physiology — Posted on 2020-10-14
2587 Tropomyosin in mugwort cross-reacts to house dust mite, eliciting non-Th2 response in allergic rhinitis patients sensitized to house dust mite
Zhang, L.; Lan, F.; Zhao, L.; Duan, S.; Zhang, N.; Zhang, H.; Zheng, M.; Wang, Q.; Zhang, X.; Wang, X.; Ying, S.; Bachert, C.
10.1101/2020.10.13.338533 — immunology — Posted on 2020-10-13
2588 Klebsiella MALDI TypeR: a web-based tool for Klebsiella identification based on MALDI-TOF mass spectrometry
Bridel, S. M.; Watts, S. C.; Judd, L. M.; Harshegyi, T.; Passet, V.; Rodrigues, C.; Holt, K. E.; Brisse, S.
10.1101/2020.10.13.337162 — bioinformatics — Posted on 2020-10-13
2590 Nanoscale architecture of a VAP-A-OSBP tethering complex at membrane contact site
De la Mora Lugo, E.; Dezi, M.; Di Cicco, A.; Bigay, J.; Gautier, R.; Manzi, J.; Castano Diez, D.; Mesmin, B.; Antonny, B.; Levy, D.
10.1101/2020.10.13.337493 — cell biology — Posted on 2020-10-13
2591 Sero-prevalence of anti-SARS-CoV-2 Antibodies in Addis Ababa, Ethiopia
Nega, B.; Addissie, A.; Mamo, G.; Deyessa, N.; Abebe, T.; Abagero, A.; Ayele, W.; Abebe, W.; Haile, T.; Argaw, R.; Amogne, W.; Belachew, A.; Desalegn, Z.; Teka, B.; Kantelhardt, E.; Wossen, M.; Abdella, S.; Tollera, G.; Tadesse, L.
10.1101/2020.10.13.337287 — microbiology — Posted on 2020-10-13
2592 Elucidating the viral and host factors enabling the cross-species transmission of primate lentiviruses from simians to humans
Tebit, D.; Nickel, G.; Gibson, R.; Carpenter, C.; Rodriguez, M.; Hathaway, N.; Bain, K.; Reyes-Rodriguez, A.; Bonogo, J.; Canaday, D.; McDonald, D.; Bailey, J.; Arts, E.
10.1101/2020.10.13.337303 — microbiology — Posted on 2020-10-13
2596 CaBagE: a Cas9-based Background Elimination strategy for targeted, long-read DNA sequencing
Wallace, A.; Sasani, T.; Swanier, J.; Gates, B.; Greenland, J.; Pedersen, B.; Varley, K.; Quinlan, A. R.
10.1101/2020.10.13.337253 — genetics — Posted on 2020-10-13
2602 Pilot production of SARS-CoV-2 related proteins in plants: a proof of concept for rapid repurposing of indoors farms into biomanufacturing facilities
Diego-Martin, B.; Gonzalez, B.; Vazquez-Vilar, M.; Selma, S.; Mateos-Fernandez, R.; Gianoglio, S.; Fernandez-del-Carmen, A.; Orzaez, D.
10.1101/2020.10.13.331306 — synthetic biology — Posted on 2020-10-13
2604 Temperature and species-dependent regulation of browning in retrobulbar fat.
Rajaii, F.; Kim, D. W.; Pan, J.; Mahoney, N. R.; Eberhart, C. G.; Qian, J.; Blackshaw, S.
10.1101/2020.10.12.333807 — physiology — Posted on 2020-10-13
2605 Structural insights on the substrate-binding proteins of the Mycobacterium tuberculosis mammalian-cell-entry (Mce) 1 and 4 complexes
Asthana, P.; Singh, D.; Pedersen, J. S.; Hynönen, M. J.; Sulu, R.; Murthy, A. V.; Laitaoja, M.; Jänis, J.; W. Riley, L.; Venkatesan, R.
10.1101/2020.09.29.317909 — biophysics — Posted on 2020-10-13
2606 METTL3 inhibitors for epitranscriptomic modulation of cellular processes
Moroz-Omori, E. V.; Huang, D.; Bedi, R. K.; Cheriyamkunnel, S. J.; Bochenkova, E.; Dolbois, A.; Rzeczkowski, M. D.; Wiedmer, L.; Caflisch, A.
10.1101/2020.09.25.311803 — biochemistry — Posted on 2020-10-13
2609 Cas9-AAV6 Gene Correction of Beta-Globin in Autologous HSCs Improves Sickle Cell Disease Erythropoiesis in Mice
Wilkinson, A. C.; Dever, D. P.; Baik, R.; Camarena, J.; Hsu, I.; Charlesworth, C. T.; Morita, C.; Nakauchi, H.; Porteus, M. H.
10.1101/2020.10.13.338319 — developmental biology — Posted on 2020-10-13
2610 Myofibrillar Structural Variability Underlies Contractile Function in Stem Cell-Derived Cardiomyocytes
Ufford, K.; Friedline, S.; Tong, Z.; Tang, V. T.; Dobbs, A. S.; Tsan, Y.-C.; Bielas, S. L.; Liu, A. P.; Helms, A. S.
10.1101/2020.10.13.336685 — cell biology — Posted on 2020-10-13
2615 UDP-glucose pyrophosphorylase 2, a regulator of glycosylation and glycogen, is essential for pancreatic cancer growth
Wolfe, A. L.; Zhou, Q.; Toska, E.; Galeas, J.; Ku, A. A.; Koche, R. P.; Bandyopadhyay, S.; Scaltriti, M.; Lebrilla, C. B.; McCormick, F.; Kim, S. E.
10.1101/2020.10.13.337998 — cancer biology — Posted on 2020-10-13
2616 The Synergism Between DHODH Inhibitors and Dipyridamole Leads to Metabolic Lethality in Acute Myeloid Leukemia
Gaidano, V.; Houshmand, M.; Vitale, N.; Carra, G.; Morotti, A.; Tenace, V.; Rapelli, S.; Sainas, S.; Pippione, A. C.; Giorgis, M.; Boschi, D.; Lolli, M. L.; Cignetti, A.; Saglio, G.; Circosta, P.
10.1101/2020.10.10.334631 — cancer biology — Posted on 2020-10-13
2617 Data-guided Multi-Map variables for ensemble refinement of molecular movies
Vant, J. W.; Sarkar, D.; Streitwieser, E.; Fiorin, G.; Skeel, R. D.; Vermaas, J. V.; Singharoy, A.
10.1101/2020.07.23.217794 — biophysics — Posted on 2020-10-13
2620 CRISPR-enhanced human adipocyte 'browning' as cell therapy for metabolic disease
Tsagkaraki, E.; Nicoloro, S.; De Souza, T.; Solivan-Rivera, J.; Desai, A.; Shen, Y.; Kelly, M.; Guilherme, A.; Henriques, F.; Ibraheim, R.; Amrani, N.; Luk, K.; Maitland, S.; Friedline, R. H.; Tauer, L.; Hu, X.; Kim, J. K.; Wolfe, S. A.; Sontheimer, E. J.; Corvera, S.; Czech, M. P.
10.1101/2020.10.13.337923 — bioengineering — Posted on 2020-10-13
2622 Mapping the substrate sequence and length of the Plasmodium M1 and M17 aminopeptidases
Malcolm, T. R.; Swiderska, K. W.; Hayes, B. K.; Drag, M.; Drinkwater, N.; McGowan, S.
10.1101/2020.10.13.338178 — biochemistry — Posted on 2020-10-13
2623 Structural impact on SARS-CoV-2 spike protein by D614G substitution
Zhang, J.; Cai, Y.; Xiao, T.; Lu, J.; Peng, H.; Sterling, S. M.; Walsh, R. M.; Rits-Volloch, S.; Sliz, P.; Chen, B.
10.1101/2020.10.13.337980 — biochemistry — Posted on 2020-10-13
2625 Landscape of allele-specific transcription factor binding in the human genome
Abramov, S.; Boytsov, A.; Bykova, D.; Penzar, D. D.; Yevshin, I.; Kolmykov, S. K.; Fridman, M. V.; Favorov, A. V.; Vorontsov, I. E.; Baulin, E.; Kolpakov, F.; Makeev, V. J.; Kulakovskiy, I. V.
10.1101/2020.10.07.327643 — genetics — Posted on 2020-10-13
2627 Degradation of SARS-CoV-2 receptor ACE2 by tobacco carcinogen-induced Skp2 in lung epithelial cells
Zhou, G.-B.; Wang, G.-Z.; Zhao, Q.; Liang, F.; Zhang, C.; Zhang, H.; Wang, J.; Chen, Z.-Y.; Wu, R.; Yu, H.; Sun, B.-B.; Feng, R.; Xu, K.-F.
10.1101/2020.10.13.337774 — cell biology — Posted on 2020-10-13
2629 Sequential infection with influenza A virus followed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to more severe disease and encephalitis in a mouse model of COVID-19.
Clark, J. J.; Penrice-Randal, R.; Sharma, P.; Kipar, A.; Dong, X.; Davidson, A. D.; Kavanagh Williamson, M.; Matthews, D. A.; Turtle, L.; Prince, T.; Hughes, G.; Patterson, E. I.; Subramaniam, K.; Sharp, J.; McLaughlin, L.; Zhou, E.-M.; Turner, J. D.; Marriott, A. E.; Colombo, S.; Pennington, S.; Biagini, G.; Owen, A.; Hiscox, J. A.; Stewart, J. P.
10.1101/2020.10.13.334532 — microbiology — Posted on 2020-10-13
2630 Massive genome decay and expansion of insertion sequences drive the evolution of a novel host-restricted bacterial pathogen
Yebra, G.; Haag, A. F.; Neamah, M. N.; Wee, B. A.; Richardson, E. J.; Horcajo, P.; Granneman, S.; Tormo-Mas, M. A.; de la Fuente, R.; Fitzgerald, J. R.; Penades, J. R.
10.1101/2020.10.13.331058 — microbiology — Posted on 2020-10-13
2631 CRISPR-Based Transcriptional Activation Tool for Silent Genes in Filamentous Fungi
Mozsik, L.; Hoekzema, M.; de Kok, N. A. W.; Bovenberg, R. A. L.; Nygard, Y.; Driessen, A. J. M.
10.1101/2020.10.13.338012 — microbiology — Posted on 2020-10-13
2632 Analysis of selection methods to develop novel phage therapy cocktails against antimicrobial resistant clinical isolates of bacteria
Haines, M. E.; Hodges, F. E.; Nale, J. Y.; Mahony, J.; van Sinderen, D.; Kaczorowska, J.; Alrashid, B.; Akter, M.; Brown, N.; Sauvageau, D.; Sicheritz-Ponten, T.; Thanki, A. M.; Millard, A.; Galyov, E. E.; Clokie, M. R.
10.1101/2020.10.13.337345 — microbiology — Posted on 2020-10-13
2633 Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies
Yan, R.; Wang, R.; Ju, B.; Yu, J.; Zhang, Y.; Liu, N.; Wang, J.; Zhang, Q.; Chen, P.; Zhou, B.; Li, Y.; Zhang, S.; Tian, L.; Zhong, X.; Cheng, L.; Ge, X.; Zhao, J.; Wang, H.-w.; Wang, X.; Zhang, Z.; Zhang, L.; Zhou, Q.
10.1101/2020.10.13.336800 — microbiology — Posted on 2020-10-13
2634 The non-coding RNA miR-17~92 is a central mediator of T cell activation
Doelz, M.; Gagnon, J. D.; Kornete, M.; Marone, R.; Bantug, G.; Kageyama, R.; Hess, C.; Ansel, K. M.; Seyres, D.; Roux, J.; Jeker, L. T.
10.1101/2020.10.13.336537 — immunology — Posted on 2020-10-13
2636 Scalable and accurate automated method for neuronal ensemble detection in spiking neural networks
Herzog, R.; Morales, A.; Mora, S.; Araya, J.; Escobar, M.-J.; Palacios, A. G.; Cofre, R.
10.1101/2020.10.12.335901 — neuroscience — Posted on 2020-10-13
2638 Influence of sensory modality and control dynamics on human path integration
Stavropoulos, A.; Lakshminarasimhan, K. J.; Laurens, J.; Pitkow, X.; Angelaki, D.
10.1101/2020.09.21.307256 — neuroscience — Posted on 2020-10-13
2639 Visual QC Protocol for FreeSurfer Cortical Parcellations from Anatomical MRI
Raamana, P. R.; Theyers, A.; Selliah, T.; Bhati, P.; Arnott, S. R.; Hassel, S.; Nanayakkara, N. D.; Scott, C. J. M.; Harris, J.; Zamyadi, M.; Lam, R. W.; Milev, R.; Mueller, D. J.; Rotzinger, S.; Frey, B. N.; Kennedy, S. H.; Black, S. E.; Lang, A.; Masellis, M.; Symons, S.; Bartha, R.; MacQueen, G. M.; CANBIND Investigator Team, ; ONDRI Study Group, ; Strother, S. C.
10.1101/2020.09.07.286807 — neuroscience — Posted on 2020-10-13
2645 1RS.1BL molecular resolution provides novel contributions to wheat improvement
Ru, Z.; Juhasz, A.; Li, D.; Deng, P.; Zhao, J.; Gao, L.; Wang, K.; Keeble-Gagnere, G.; Yang, Z.; Li, G.; Wang, D.; Bose, U.; Colgrave, M.; Kong, C.; Zhao, G.; Zhang, X.; Liu, X.; Cui, G.; Wang, Y.; Niu, Z.; Wu, L.; Cui, D.; Jia, J.; Appels, R.; Kong, X.
10.1101/2020.09.14.295733 — genomics — Posted on 2020-10-13
2646 SIRT1 activity orchestrates ECM expression during hESC-chondrogenic differentiation
Smith, C. A.; Humphreys, P. A.; Bates, N.; Naven, M. A.; Cain, S. A.; Kimber, S. J.; Dvir Ginzbrg, M.
10.1101/2020.05.12.087957 — developmental biology — Posted on 2020-10-13
2658 ELOVL2 is required for robust visual function in zebrafish
Dasyani, M.; Gao, F.; Xu, Q.; Van Fossan, D.; Zhang, E.; Pinto, A. F. M.; Saghatelian, A.; Skowronska-Krawczyk, D.; Chao, D. L.
10.1101/2020.10.13.336974 — molecular biology — Posted on 2020-10-13
2659 Identification of a peroxidase inhibitor that enhances kanamycin activity
Hui, Z.; Liu, S.; Cui, R.; Zhou, B.; Hu, C.; Zhang, M.; Deng, Q.; Cheng, S.; Luo, Y.; Chen, H.; Wu, J.; Lu, Y.; Liu, X.; Dai, L.; Huang, W.
10.1101/2020.10.12.336933 — microbiology — Posted on 2020-10-13
2660 Reliability and sensitivity of two whole-brain segmentation approaches included in FreeSurfer - ASEG and SAMSEG
Sederevicius, D.; Pineiro, D. V.; Sorensen, O.; van Leemput, K.; Iglesias, J. E.; Dalca, A. V.; Greve, D.; Fischl, B.; Bjornerud, A.; Walhovd, K. B.; Fjell, A. M.
10.1101/2020.10.13.335737 — neuroscience — Posted on 2020-10-13
2662 Multi-Modal Single-Molecule Imaging with Continuously Controlled Spectral-resolution (CoCoS) Microscopy
Jeffet, J.; Michaeli-Hoch, Y.; Torchinsky, D.; Israel-Elgali, I.; Shomron, N.; Craggs, T. D.; Ebenstein, Y.
10.1101/2020.10.13.330910 — biophysics — Posted on 2020-10-13
2663 Heterogeneous Mediation Analysis for Causal Inference
Xue, F.; Tang, X.; Kim, G.; Aiello, A.; Koenen, K.; Galea, S.; Wildman, D.; Uddin, M.; Qu, A.
10.1101/2020.10.13.336826 — bioinformatics — Posted on 2020-10-13
2664 Presence and Transmission of Mitochondrial Heteroplasmic Mutations in Human Populations of European and African Ancestry
Liu, C.; Fetterman, J. L.; Qian, Y.; Sun, X.; Blackwell, T.; Pitsillides, A. N.; Cade, B. E.; Wang, H.; Raffield, L. M.; Lange, L.; Anugu, P.; Abecasis, G.; Cupples, L. A.; Redline,, S.; Correa, A.; Vasan, R.; Wilson, J.; Ding, J.; Levy, D.
10.1101/2020.10.13.337071 — genetics — Posted on 2020-10-13
2670 Aggregation of Cohorts for Histopathological Diagnosis with Deep Morphological Analysis
Park, J.; Chung, Y. R.; Kong, S. T.; Kim, Y. W.; Park, H.; Kim, K.; Kim, D.-I.; Jung, K.-H.
10.1101/2020.10.13.337014 — pathology — Posted on 2020-10-13
2671 SepF is the FtsZ-anchor in Archaea: implications for cell division in the Last Universal Common Ancestor
Pende, N.; Sogues, A.; Megrian, D.; Palabikyan, H.; Sartori-Rupp, A.; Grana, M.; Rittmann, S. K.- M. R.; Wehenkel, A. M.; Alzari, P.; Gribaldo, S.
10.1101/2020.10.06.328377 — microbiology — Posted on 2020-10-13
2672 Mutation Maker, An Open Source Oligo Design Platform for Protein Engineering
Hiraga, K.; Mejzlik, P.; Marcisin, M.; Vostrosablin, N.; Gromek, A.; Arnold, J.; Wiewiora, S.; Svarba, R.; Prihoda, D.; Clarova, K.; Klempir, O.; Navratil, J.; Tupa, O.; Vazquez-Otero, A.; Walas, M. W.; Holy, L.; Spale, M.; Kotowski, J.; Dzamba, D.; Temesi, G.; Russell, J. H.; Marshall, N. M.; Murphy, G. S.; Bitton, D. A.
10.1101/2020.06.26.171819 — bioinformatics — Posted on 2020-10-13
2674 Widespread lateral gene transfer among grasses
Hibdige, S. G. S.; Raimondeau, P.; Christin, P.-A.; Dunning, L. T.
10.1101/2020.02.17.952150 — evolutionary biology — Posted on 2020-10-13
2675 Plasmodium DEH is ER-localized and crucial for oocyst mitotic division during malaria transmission
Guttery, D. S.; Pandey, R.; Ferguson, D.; Wall, R.; Brady, D.; Gupta, D.; Holder, A. A.; Tewari, R.
10.1101/2020.07.01.182774 — cell biology — Posted on 2020-10-13
2680 Charge-Driven Phase Condensation of RNA and Proteins Suggests Broad Role of Phase Separation in Cytoplasmic Environments
Dutagaci, B.; Nawrocki, G.; Goodluck, J.; Ashkarran, A. A.; Hoogstraten, C. G.; Lapidus, L. J.; Feig, M.
10.1101/2020.04.23.057901 — biophysics — Posted on 2020-10-13
2681 Quantitative intravital imaging reveals in vivo dynamics of physiological-stress induced mitophagy.
Wrighton, P. J.; Shwartz, A.; Heo, J.-M.; Quenzer, E. D.; LaBella, K. A.; Harper, J. W.; Goessling, W.
10.1101/2020.03.26.010405 — cell biology — Posted on 2020-10-13
2683 Multiple memories can be simultaneously reactivated during sleep as effectively as a single memory
Schechtman, E.; Antony, J. W.; Lampe, A.; Wilson, B. J.; Norman, K. A.; Paller, K. A.
10.1101/662015 — neuroscience — Posted on 2020-10-13
2684 Transient astrocytic Gq signaling underlies remote memory enhancement
Iwai, Y.; Ozawa, K.; Yahagi, K.; Tanaka, M.; Itohara, S.; Hirase, H.
10.1101/753095 — neuroscience — Posted on 2020-10-13
2685 Cryo-EM structural studies of the agonist complexed human TRPV4 ion-channel reveals novel structural rearrangements resulting in an open-conformation
Botte, M.; Ulrich, A. K. C.; Adaixo, R.; Gnutt, D.; Brockmann, A.; Bucher, D.; Chami, M.; Bocquet, N.; Ebbinghaus-Kintscher, U.; Puetter, V.; Becker, A.; Egner, U.; Stahlberg, H.; Hennig, M.; Holton, S. J.
10.1101/2020.10.13.334797 — molecular biology — Posted on 2020-10-13
2690 A small interfering RNA (siRNA) database for SARS-CoV-2
Medeiros, I. G.; Khayat, A. S.; Stransky, B.; dos Santos, S. E. B.; Assumpcao, P. P.; de Souza, J. E. S.
10.1101/2020.09.30.321596 — bioinformatics — Posted on 2020-10-13
2691 Cold sensitivity of the SARS-CoV-2 spike ectodomain
Edwards, R. J.; Mansouri, K.; Stalls, V.; Manne, K.; Watts, B.; Parks, R.; Janowska, K.; Gobeil, S. M. C.; Kopp, M.; Li, D.; Lu, X.; Mu, Z.; Deyton, M.; Oguin, T.; Sprenz, J.; Williams, W.; Saunders, K.; Montefiori, D.; Sempowski, G. D.; Henderson, R.; Alam, M.; Haynes, B. F.; Acharya, P.
10.1101/2020.07.12.199588 — biochemistry — Posted on 2020-10-13
2692 Alternate primers for whole-genome SARS-CoV-2 sequencing
Cotten, M.; Bugembe, D. L.; Kaleebu, P.; Phan, M. V. T.
10.1101/2020.10.12.335513 — genomics — Posted on 2020-10-13
2693 Reconstructing SARS-CoV-2 response signaling and regulatory networks
Ding, J.; Lugo-Martinez, J.; Yuan, Y.; Kotton, D. N.; Bar-Joseph, Z.
10.1101/2020.06.01.127589 — systems biology — Posted on 2020-10-13
2694 hACE2 peptide mimics block SARS-CoV-2 Pulmonary Cells Infection
Karoyan, P.; Vieillard, V.; Odile, E.; Denis, A.; guihot, a.; luyt, c. e.; Gomes-Morales, L.; Grondin, P.; Lequin, O.
10.1101/2020.08.24.264077 — pharmacology and toxicology — Posted on 2020-10-13
2695 Pharmacological inhibition of nonsense-mediated RNA decay augments HLA class I-mediated presentation of neoepitopes in MSI CRC
Becker, J. P.; Helm, D.; Rettel, M.; Stein, F.; Hernandez-Sanchez, A.; Urban, K.; Gebert, J.; Kloor, M.; Neu-Yilik, G.; von Knebel Doeberitz, M.; Hentze, M. W.; Kulozik, A. E.
10.1101/2020.10.13.319970 — cancer biology — Posted on 2020-10-13
2696 Genetic Landscape of Gullah African Americans
Zimmerman, K. D.; Schurr, T. G.; Chen, W.-M.; Nayak, U.; Mychaleckyj, J. C.; Quet, Q.; Moultrie, L. H.; Divers, J.; Keene, K. L.; Kamen, D. L.; Gilkeson, G. S.; Hunt, K. J.; Spruill, I. J.; Fernandes, J. K.; Aldrich, M.; Reich, D. E.; Garvey, W. T.; Langefeld, C. D.; Sale, M. M.; Ramos, P. S.
10.1101/2020.10.12.336347 — genetics — Posted on 2020-10-13
2699 Bifractal nature of chromosome contact maps
Pigolotti, S.; Jensen, M. H.; Zhan, Y.; Tiana, G.
10.1101/686279 — biophysics — Posted on 2020-10-13
2700 Dynamic tracking and identification of tissue-specific secretory proteins in the circulation of live mice
Kim, K.-e.; Park, I.; Kim, J.; Kang, M.-G.; Choi, W. G.; Shin, H.; Kim, J.-S.; Rhee, H.-W.; Suh, J. M.
10.1101/2020.09.21.299198 — biochemistry — Posted on 2020-10-13
2701 Effectively control of a viral disease with a high transmission rate through selective predation
Chen, Y. G.; Wang, M.; Zhao, Z.; Weng, S. P.; Yang, J. C.; Liu, S. Y.; Liu, C.; Yuan, F. H.; Ai, B.; Zhang, H. Q.; Zhang, M. Y.; Lu, L. R.; Yuan, K.; Yu, Z. L.; Mo, B. B.; Zhong, Z. W.; Zheng, L. W.; Feng, G. C.; Li, S. C.; He, J. G.
10.1101/2020.09.24.311563 — ecology — Posted on 2020-10-13
2702 Temperature and species-dependent regulation of browning in retrobulbar fat.
Rajaii, F.; Kim, D. W.; Pan, J.; Mahoney, N. R.; Eberhardt, C. G.; Qian, J.; Blackshaw, S.
10.1101/2020.10.12.333807 — physiology — Posted on 2020-10-12
2703 Vulnerability of ARID1A deficient cancer cells to pyrimidine synthesis blockade
Li, Z.; Mi, S.; Osagie, O. I.; Ji, J.; Yang, C.-P. H.; Schwartz, M.; Hui, P.; Huang, G. S.
10.1101/2020.10.12.331975 — cancer biology — Posted on 2020-10-12
2704 Single cell transcriptome analysis defines novel heterogeneity within the pancreatic ductal tree
Hendley, A. M.; Rao, A. A.; Leonhardt, L.; Ashe, S.; Smith, J. A.; Giacometti, S.; Peng, X. L.; Jiang, H.; Berrios, D.; Pawlak, M.; Li, L. Y.; Lee, J.; Collisson, E. A.; Anderson, M.; Fragiadakis, G. K.; Yeh, J. J.; Chun, J. Y.; Kim, G. E.; Weaver, V. M.; Hebrok, M.
10.1101/2020.10.12.336784 — bioinformatics — Posted on 2020-10-12
2706 Within-patient genetic diversity of SARS-CoV-2
Kuipers, J.; Batavia, A. A.; Jablonski, K. P.; Bayer, F.; Borgsmüller, N.; Dondi, A.; Dragan, M.-A.; Ferreira, P.; Jahn, K.; Lamberti, L.; Pirkl, M.; Posada-Cespedes, S.; Topolsky, I.; Nissen, I.; Santacroce, N.; Burcklen, E.; Schär, T.; Capece, V.; Beckmann, C.; Kobel, O.; Noppen, C.; Redondo, M.; Nadeau, S.; Seidel, S.; Santamaria de Souza, N.; Beisel, C.; Stadler, T.; Beerenwinkel, N.
10.1101/2020.10.12.335919 — genomics — Posted on 2020-10-12
2710 A Systematic Review and Meta-analysis for Association of Helicobacter pylori Colonization and Celiac Disease
Amlashi, F. I.; Norouzi, Z.; Sohrabi, A.; Shirzad-Aski, H.; Norouzi, A.; Ashkbari, A.; Gilani, N.; Fatemi, S. A.; Besharat, S.
10.1101/2020.10.12.335836 — microbiology — Posted on 2020-10-12
2712 Scalable and accurate automated method for neuronal ensemble detection in spiking neural networks
Herzog, R.; Morales, A.; Mora, S.; Araya, J.; Escobar, M.-J.; Palacios, A. G.; Cofre, R.
10.1101/2020.10.12.335901 — neuroscience — Posted on 2020-10-12
2714 Development of an orally-administrable tumor vasculature-targeting therapeutic using annexin A1-binding D-peptides
Fukuda, M. N.; Nonaka, M.; Mabashi-Asazuma, H.; Jarvis, D. L.; Yamasaki, K.; Akama, T.; Nagaoka, M.; Sasai, T.; Kimura-Takagi, I.; Suwa, Y.; Yaegashi, T.; Huang, C.-T.; Nishizawa-Harada, C.
10.1101/2020.10.12.335851 — pharmacology and toxicology — Posted on 2020-10-12
2718 The genomic formation of First American ancestors in East and Northeast Asia
Ning, C.; Fernandes, D.; Changmai, P.; Flegontova, O.; Yuncu, E.; Maier, R.; Altinisik, N. E.; Kassian, A. S.; Krause, J.; Lalueza-Fox, C.; Manica, A.; Potter, B. A.; Robbeets, M.; Sirak, K.; Siska, V.; Vajda, E. J.; Vyazov, L. A.; Wang, K.; Wang, L.; Wu, X.; Xiao, X.; Zhang, F.; Reich, D.; Schiffels, S.; Pinhasi, R.; Cui, Y.; Flegontov, P.
10.1101/2020.10.12.336628 — genetics — Posted on 2020-10-12
2723 A Large-Scale Internal Validation Study of Unsupervised Virtual Trichrome Staining Technologies on Non-alcoholic Steatohepatitis Liver Biopsies
Levy, J.; Azizgolshani, N.; Andersen, M.; Suriawinata, A. A.; Liu, X.; Lisovsky, M.; Ren, B.; Bobak, C. A.; Christensen, B.; Vaickus, L. J.
10.1101/2020.07.03.187237 — pathology — Posted on 2020-10-12
2724 Brain-Restricted mTOR Inhibition with Binary Pharmacology
Zhang, Z.; Fan, Q.; Luo, X.; Lou, K. J.; Weiss, W. A.; Shokat, K.
10.1101/2020.10.12.336677 — cancer biology — Posted on 2020-10-12
2726 Long-range quantum coherence of the photosystem 2 complexes in living cyanobacteria
Rammler, T. D.; Wackenhut, F.; zur Oven-Krockhaus, S.; Rapp, J.; Forchhammer, K.; Harter, K. J. W.; Meixner, A. J.
10.1101/2019.12.13.875344 — biophysics — Posted on 2020-10-12
2727 Prediction of GPI-Anchored proteins with pointer neural networks
Gislason, M. H.; Nielsen, H.; Almagro Armenteros, J. J.; Johansen, A. R.
10.1101/838680 — bioinformatics — Posted on 2020-10-12
2731 Sustained nitrogen loss in a symbiotic association of Comammox Nitrospira and Anammox bacteria
Gottshall, E. Y.; Bryson, S. J.; Cogert, K. I.; Landreau, M.; Sedlacek, C. J.; Stahl, D. A.; Daims, H.; Winkler, M.
10.1101/2020.10.12.336248 — ecology — Posted on 2020-10-12
2732 Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function.
Golden, E. J.; Larson, E. D.; Shechtman, L. A.; Trahan, G. D.; Gaillard, D.; Fellin, T. J.; Scott, J. K.; Jones, K. L.; Barlow, L. A.
10.1101/2020.10.12.336602 — developmental biology — Posted on 2020-10-12
2738 Physicochemical and metabolic constraints for thermodynamics-based stoichiometric modelling under mesophilic growth conditions
Tomi-Andrino, C.; Norman, R.; Millat, T.; Soucaille, P.; Winzer, K.; Barrett, D. A.; King, J.; Kim, D.-H.
10.1101/2020.02.03.932855 — systems biology — Posted on 2020-10-12
2740 Metabolic Reprogramming by In Utero Maternal Benzene Exposure
Koshko, L.; Debarba, L. K.; Sacla, M.; Lima, J. B. M.; Didyuk, O.; Fakhoury, P.; Sadagurski, M.
10.1101/2020.10.12.336313 — pharmacology and toxicology — Posted on 2020-10-12
2742 Ancestral Haplotype Reconstruction in Endogamous Populations using Identity-By-Descent
Finke, K.; Kourakos, M.; Brown, G.; Dang, H. T.; Tan, S. J. S.; Simons, Y. B.; Schaffer, A. A.; Kember, R. L.; Bucan, M.; Mathieson, S.
10.1101/2020.01.15.908459 — bioinformatics — Posted on 2020-10-12
2746 Taxonomic hypotheses and the biogeography of speciation in the Tiger Whiptail complex (Aspidoscelis tigris: Squamata, Teiidae)
Chafin, T. K.; Douglas, M. R.; Anthonysamy, W. J. B.; Sullivan, B. K.; Walker, J. M.; Cordes, J. E.; Douglas, M. E.
10.1101/2020.10.05.327270 — evolutionary biology — Posted on 2020-10-12
2750 Gut Microbiota-Targeted Diets Modulate Human Immune Status
Wastyk, H. C.; Fragiadakis, G. K.; Perelman, D.; Dahan, D.; Merrill, B. D.; Yu, F. B.; Topf, M.; Gonzalez, C.; Robinson, J. L.; Elias, J. E.; Sonnenburg, E.; Gardner, C. D.; Sonnenburg, J.
10.1101/2020.09.30.321448 — microbiology — Posted on 2020-10-12
2751 Previously unrecorded distribution of marine sediments derived yeast isolates revealed by DNA barcoding
PrasannaKumar, C.; Velmurugan, S.; Subramanian, K.; Pugazhvendan, S. R.; Senthil Nagaraj, D.; Feroz Khan, K.; Sadaiappan, B.; Manokaran, S.; Hemalatha, K. R.; Sivamaruthi, B. S.; Chaiyasut, C.
10.1101/2020.08.29.273490 — microbiology — Posted on 2020-10-12
2753 Gut Dysbiosis with a Pathobiont Shifts the Intestinal Microbiota Profile and Accelerates Lupus Nephritis
Valiente, G. R.; Munir, A.; Hart, M. L.; Blough, P.; Wada, T. T.; Dalan, E. E.; Willis, W. L.; Wu, L.-C.; Freud, A. G.; Jarjour, W. N.
10.1101/2020.10.12.310763 — immunology — Posted on 2020-10-12
2755 Multiple pathways of LRRK2-G2019S / Rab10 interaction in dopaminergic neurons
Fellgett, A.; Middleton, C. A.; Munns, J.; Ugbode, C.; Jaciuch, D.; Wilson, L.; Chawla, S.; Elliott, C.
10.1101/2020.09.28.316992 — neuroscience — Posted on 2020-10-12
2757 Multiscale integration organizes hierarchical computation in human auditory cortex
Norman-Haignere, S. V.; Long, L. K.; Devinsky, O.; Doyle, W.; Irobunda, I.; Merricks, E.; Feldstein, N. A.; McKhann, G. M. V.; Schevon, C.; Flinker, A.; Mesgarani, N.
10.1101/2020.09.30.321687 — neuroscience — Posted on 2020-10-12
2758 Thalamic encoding of lexical status is lateralized during reading aloud
Wang, D.; Lipski, W.; Bush, A.; Chrabaszcz, A.; Dastolfo-Hromack, C.; Dickey, M. W.; Fiez, J.; Richardson, R. M.
10.1101/2020.07.30.229898 — neuroscience — Posted on 2020-10-12
2762 Error propagation in constraint-based modeling of Chinese hamster ovary cells
Szeliova, D.; Iurashev, D.; Ruckerbauer, D. E.; Koellensperger, G.; Borth, N.; Melcher, M.; Zanghellini, J.
10.1101/2020.07.09.195594 — systems biology — Posted on 2020-10-12
2765 Modular metabolite assembly in C. elegans depends on carboxylesterases and formation of lysosome-related organelles
Le, H. H.; Wrobel, C. J.; Cohen, S. M.; Yu, J.; Park, H.; Helf, M. J.; Curtis, B. J.; Kruempel, J.; Rodrigues, P. R.; Hu, P. J.; Sternberg, P. W.; Schroeder, F. C.
10.1101/2020.08.22.262956 — biochemistry — Posted on 2020-10-12
2767 Integrated analysis of multimodal single-cell data
Hao, Y.; Hao, S.; Andersen-Nissen, E.; Mauck, W. M.; Zheng, S.; Butler, A.; Lee, M. J.; Wilk, A. J.; Darby, C.; Zagar, M.; Hoffman, P.; Stoeckius, M.; Papalexi, E.; Mimitou, E. P.; Jain, J.; Srivastava, A.; Stuart, T.; Fleming, L. B.; Yeung, B.; Rogers, A. J.; McElrath, J. M.; Blish, C. A.; Gottardo, R.; Smibert, P.; Satija, R.
10.1101/2020.10.12.335331 — genomics — Posted on 2020-10-12
2768 Sequences in the cytoplasmic tail of SARS-CoV-2 spike facilitate syncytia formation
Cattin-Ortola, J.; Welch, L.; Maslen, S. L.; Skehel, J. M.; Papa, G.; James, L. C.; Munro, S.
10.1101/2020.10.12.335562 — cell biology — Posted on 2020-10-12
2770 A combination of metagenomic and cultivation approaches reveals hypermutator phenotypes within Vibrio cholerae infected patients
Levade, I.; Khan, A. I.; Chowdhury, F.; Calderwood, S. B.; Ryan, E. T.; Harris, J. B.; LaRocque, R. C.; Bhuiyan, T. R.; Qadri, F.; Weil, A. A.; Shapiro, B. J.
10.1101/2020.10.11.333682 — microbiology — Posted on 2020-10-12
2771 Leptospira surface protein LigA plays a multifaceted role in modulating the host innate immune response
Kumar, A.; Varma, V. P.; Sridhar, K.; Abdullah, M.; Vyas, P.; Ashiq, M.; Chang, Y.-F.; Faisal, S. M.
10.1101/2020.10.12.329177 — immunology — Posted on 2020-10-12
2774 A dominant-negative variant in the dopamine transporter PDZ-binding motif is linked to parkinsonism and neuropsychiatric disease
Herborg, F.; Jensen, K. L.; Tolstoy, S.; Arends, N. V.; Posselt, L. P.; Shekar, A.; Aguilar, J.; Lund, V. K.; Erreger, K.; Rickhag, M.; Lycas, M. D.; Lonsdale, M. N.; Rahbek-Clemmensen, T.; Sorensen, A. T.; Newman, A. H.; Loekkegaard, A.; Kjaerulff, O.; Werge, T.; Moeller, L. B.; Matthies, H. J.; Galli, A.; Hjermind, L. E.; Gether, U.
10.1101/2020.10.12.336461 — neuroscience — Posted on 2020-10-12
2776 Using Machine Learning To Develop A Fully Automated Soybean Nodule Acquisition Pipeline (SNAP)
Jubery, T. Z.; Carley, C.; Sarkar, S.; Singh, A.; Ganapathysubramanian, B.; Singh, A. K.
10.1101/2020.10.12.336156 — plant biology — Posted on 2020-10-12
2777 LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency
O'Connor, M. N.; Kallenberg, D. M.; Jackstadt, R.; Watson, A. H.; Alatsatianos, M.; Ohme, J.; Camilli, C.; Pilotti, C.; Dritsoula, A.; Bowers, C. E.; Dowsett, L.; George, J.; Wang, X.; Ager, A.; Sansom, O. J.; Moss, S. E.; Greenwood, J.
10.1101/2020.10.12.334359 — cancer biology — Posted on 2020-10-12
2779 Defocus-dependent Thon-ring fading
Glaeser, R. M.; Hagen, W. J. H.; Han, B.-G.; Henderson, R.; McMullan, G.; Russo, C. J.
10.1101/2020.10.12.336214 — biophysics — Posted on 2020-10-12
2781 Differential gene expression in the interactome of the Human Dopamine transporter in the context of Parkinson's disease
NAVARRO, R. C.; Ligia Scott, A.; Allison Philot, E.; Atencio, L.; Fernandez Ponce, C.; Aroca Martinez, G.; Cadena Bonfanti, A.; Gomez Escorcia, l.; Navarro Quiroz, E.
10.1101/2020.10.12.336388 — bioinformatics — Posted on 2020-10-12
2784 A synthetic lethal interaction with a viral-induced hypomorph of GBF1
Navare, A. T.; Mast, F. D.; Olivier, J. P.; Bertomeu, T. D.; Coulombe-Huntington, J.; Neal, M.; Tyers, M.; Aitchison, J. D.
10.1101/2020.10.12.336487 — molecular biology — Posted on 2020-10-12
2786 A novel and conserved cell wall enzyme that can substitute for the Lipid II synthase MurG
Zhang, L.; Ramijan, K.; Carrion, V.; van der Aart, L.; Willemse, J.; Van Wezel, G.; Claessen, D.
10.1101/2020.10.12.336396 — microbiology — Posted on 2020-10-12
2787 Host-pathogen co-existence incurs reproductive costs
Strubbe, D.; Haesendonck, R.; Verbrugghe, E.; Lens, L.; Ducatelle, R.; Croubels, S.; Haesebrouck, F.; Martel, A.; Pasmans, F.
10.1101/2020.10.12.336370 — microbiology — Posted on 2020-10-12
2788 Synapse-specific direction selectivity in retinal bipolar cell axon terminals
Matsumoto, A.; Agbariah, W.; Nolte, S. S.; Andrawos, R.; Levi, H.; Sabbah, S.; Yonehara, K.
10.1101/2020.10.12.335810 — neuroscience — Posted on 2020-10-12
2789 Presynaptic accumulation of α-synuclein causes synaptopathy and progressive neurodegeneration
Bridi, J. C.; Bereczki, E.; Smith, S. K.; Pocas, G. M.; Kottler, B.; Domingos, P.; Elliott, C. J.; Aarsland, D.; Hirth, F.
10.1101/2020.10.12.335778 — neuroscience — Posted on 2020-10-12
2792 TRAF4 inhibits bladder cancer progression by promoting BMP/SMAD signalling pathway
Iyengar, P. V.; Marvin, D. L.; Lama, D.; Tan, T. Z.; Suriyamurthy, S.; Xie, F.; van Dinther, M.; Mei, H.; Verma, C. S.; Zhang, L.; Ritsma, L.; ten Dijke, P.
10.1101/2020.10.12.335588 — cancer biology — Posted on 2020-10-12
2802 Did the Himalayan Uplift Drive Evolution of Aquatic Biodiversity Across Asia? Snowtrout (Cyprinidae: Schizothorax) as a Test Case
Regmi, B.; Douglas, M. R.; Edds, D. R.; Wangchuk, K.; Lu, C.; Khanal, G. P.; Norbu, P.; Norbu, S.; Dorji, S.; Tshering, S.; Angel, Z.; Chafin, T. K.; Zbinden, Z. D.; Douglas, M. E.
10.1101/2020.10.12.336149 — evolutionary biology — Posted on 2020-10-12
2803 Genome-enabled inference of functional genetic variants in the face, brain and behavior
Patil, C. K.; Sylvester, J. B.; Abdilleh, K.; Norsworthy, M. W.; Pottin, K.; Malinsky, M.; Bloomquist, R.; Johnson, Z.; McGrath, P. T.; Streelman, J. T.
10.1101/2020.10.12.336453 — evolutionary biology — Posted on 2020-10-12
2804 A high-throughput amplicon sequencing approach for population-wide species diversity and composition survey
Tay, W. T.; Court, L. N.; Macfadyen, S.; Jacomb, F.; Vyskocilova, S.; Colvin, J.; De Barro, P. J.
10.1101/2020.10.12.336545 — evolutionary biology — Posted on 2020-10-12
2809 A CRISPR interference platform for selective downregulation of gene expression in Borrelia burgdorferi
Takacs, C. N.; Scott, M.; Chang, Y.; Kloos, Z. A.; Irnov, I.; Rosa, P. A.; Liu, J.; Jacobs-Wagner, C.
10.1101/2020.10.12.335471 — microbiology — Posted on 2020-10-12
2811 Prenatal exposure to EDCs dis-integrates and reconstitutes neuromolecular-behavioral relationships in adult rats
Hernandez Scudder, M. E.; Young, R. L.; Thompson, L. M.; Kore, P.; Crews, D.; Hofmann, H. A.; Gore, A. C.
10.1101/2020.10.12.335984 — neuroscience — Posted on 2020-10-12
2815 Imaging stable isotope labelling kinetics (iSILK) for following spatial Aβ plaque aggregation dynamics in evolving Alzheimers disease pathology
Michno, W.; Stringer, K. M.; Enzlein, T.; Passarelli, M.; Escrig, S.; Blennow, K.; Zetterberg, H.; Meibom, A.; Hopf, C.; Edwards, F. A.; Hanrieder, J.
10.1101/2020.10.12.335828 — neuroscience — Posted on 2020-10-12
2816 Racial and ethnic imbalance in neuroscience reference lists and intersections with gender
Bertolero, M. A.; Dworkin, J. D.; David, S. U.; Lloreda, C. L.; Srivastava, P.; Stiso, J.; Zhou, D.; Dzirasa, K.; Fair, D. A.; Kaczkurkin, A. N.; Marlin, B. J.; Shohamy, D.; Uddin, L. Q.; Zurn, P.; Bassett, D. S.
10.1101/2020.10.12.336230 — neuroscience — Posted on 2020-10-12
2818 Discovery of the first selective M4 muscarinic acetylcholine receptor antagonists with in vivo anti-parkinsonian and anti-dystonic efficacy
Moehle, M. S.; Bender, A. M.; Dickerson, J. W.; Foster, D. J.; Donsante, Y.; Peng, W.; Bryany, Z. K.; Bridges, T. M.; Chang, S.; Watson, K. J.; O'Neill, J. C.; Engers, J. L.; Peng, L.; Rodriguez, A.; Niswender, C. M.; Lindsley, C. W.; Conn, P. J.; Rook, J. M.
10.1101/2020.10.12.324152 — pharmacology and toxicology — Posted on 2020-10-12
2820 D614G mutation alters SARS-CoV-2 spike conformational dynamics and protease cleavage susceptibility at the S1/S2 junction
Gobeil, S.; Janowska, K.; McDowell, S.; Mansouri, K.; Parks, R.; Manne, K.; Stalls, V.; Kopp, M.; Henderson, R.; Edwards, R. J.; Haynes, B. F.; Acharya, P.
10.1101/2020.10.11.335299 — biophysics — Posted on 2020-10-12
2823 Determining subpopulation methylation profiles from bisulfite sequencing data of heterogeneous samples using DXM
Fong, J.; Gardner, J. R.; Andrews, J. M.; Cashen, A. F.; Payton, J. E.; Weinberger, K. Q.; Edwards, J. R.
10.1101/2020.10.12.333153 — bioinformatics — Posted on 2020-10-12
2824 SPLICE-q: a Python tool for genome-wide quantification of splicing efficiency
R Melo Costa, V.; Pfeuffer, J.; Louloupi, A.; V Orom, U. A.; Piro, R. M.
10.1101/2020.10.12.318808 — bioinformatics — Posted on 2020-10-12
2825 The evolution of ecological flexibility, large brains, and long lives: capuchin monkey genomics revealed with fecalFACS
Orkin, J. D.; Montague, M. J.; Tejada-Martinez, D.; de Manuel, M.; del Campo, J.; Cheves Hernandez, S.; Di Fiore, A.; Fontsere, C.; Hodgson, J. A.; Janiak, M. C.; Kuderna, L. F. K.; Lizano, E.; Pia Martin, M.; Niimura, Y.; Perry, G. H.; Soto Valverde, C.; Tang, J.; Warren, W. C.; de Magalhaes, J. P.; Kawamura, S.; Marques-Bonet, T.; Krawetz, R.; Melin, A. D.
10.1101/366112 — genomics — Posted on 2020-10-12
2826 Alternate primers for whole-genome SARS-CoV-2 sequencing
Cotten, M.; Bugembe, D. L.; Kaleebu, P.; Phan, M. V. T.
10.1101/2020.10.12.335513 — genomics — Posted on 2020-10-12
2829 SARS-CoV-2 infects carotid arteries: implications for vascular disease and organ injury in COVID-19
Pfefferle, S.; Guenther, T.; Puelles, V.; Heinrich, F.; Noerz, D.; Czech-Sioli, M.; Carstens, A.; Krasemann, S.; Wong, M.; Oestereich, L.; Magnus, T.; Allweiss, L.; Edler, C.; Schroeder, A.-S.; Dandri, M.; Huber, T.; Glatzel, M.; Pueschel, K.; Grundhoff, A.; Luetgehetmann, M.; Aepfelbacher, M.; Fischer, N.
10.1101/2020.10.10.334458 — microbiology — Posted on 2020-10-12
2831 SARS-CoV-2 spike protein-mediated cell signaling in lung vascular cells
Suzuki, Y. J.; Nikolaienko, S. I.; Dibrova, V. A.; Dibrova, Y. V.; Vasylyk, V. M.; Novikov, M. Y.; Shults, N. V.; Gychka, S. G.
10.1101/2020.10.12.335083 — pathology — Posted on 2020-10-12
2832 Lipids in xylem sap of woody plants across the angiosperm phylogeny
Schenk, H. J.; Michaud, J. M.; Mocko, K.; Espino, S.; Melendres, T.; Roth, M. R.; Welti, R.; Kaack, L.; Jansen, S.
10.1101/763771 — plant biology — Posted on 2020-10-12
2833 Delta- and theta-band cortical tracking and phase-amplitude coupling to sung speech by infants
Attaheri, A.; Ni Choisdealbha, A.; Di Liberto, G.; Rocha, S.; Brusini, P.; Mead, N.; Olawole-Scott, H.; Boutris, P.; Gibbon, S.; Williams, I.; Grey, C.; Flanagan, S.; Goswami, U.
10.1101/2020.10.12.329326 — neuroscience — Posted on 2020-10-12
2836 Chromosome-scale assembly of the genome of Salix dunnii reveals a male-heterogametic sex determination system on chromosome 7
He, L.; Jia, K.-H.; Zhang, R.-G.; Wang, Y.; Shi, T.-L.; Li, Z.-C.; Zeng, S.-W.; Cai, X.-J.; Wagner, N. D.; Hoerandl, E.; Muyle, A.; Yang, K.; Charlesworth, D. D.; Mao, J.-F.
10.1101/2020.10.09.333229 — genomics — Posted on 2020-10-12
2837 Transcriptome-wide Mendelian randomization study prioritising novel tissue-dependent genes for glioma susceptibility
Robinson, J. W.; Martin, R.; Tsavachidis, S.; Howell, A.; Relton, C.; Armstrong, G.; Bondy, M.; Zheng, J.; Kurian, K.
10.1101/2020.10.12.335661 — genetics — Posted on 2020-10-12
2840 A Sequence determinant in 3'UTR of mRNAs for Nuclear Retention by Paraspeckles
Jacq, A.; Becquet, D.; Boyer, B.; Guillen, S.; Bello-Goutierrez, M.-M.; Blanchard, M.-P.; Villard, C.; Belghazi, M.; Torres, M.; Franc, J.-L.; Francois-Bellan, A.-M.
10.1101/2020.07.19.206417 — molecular biology — Posted on 2020-10-12
2844 Combinatorial CAR design improves target restriction
Köksal, H.; Dillard, P.; Juzeniene, A.; Kvalheim, G.; Smeland, E. B.; Myklebust, J. H.; Inderberg, E. M.; Walchli, S.
10.1101/2020.10.09.333724 — immunology — Posted on 2020-10-12
2850 Understanding the phase separation characteristics of nucleocapsid protein provides a new therapeutic opportunity against SARS-CoV-2
Zhao, D.; Xu, W.; Zhang, X.; Wang, X.; Yuan, E.; Xiong, Y.; Wu, S.; Li, S.; Wu, N.; Tian, T.; Feng, X.; Shu, H.; Lang, P.; Shen, X.; Li, H.; Li, P.; Zeng, J.
10.1101/2020.10.09.332734 — biophysics — Posted on 2020-10-12
2851 Tumor edge architecture in glioblastoma is constructed by inter-cellular signals from vascular endothelial cells
Bastola, S.; Pavlyukov, M. S.; Ghochani, Y.; Muthukrishnan, D.; Cho, H. J.; Lee, Y.; Sohrabi, A.; Seidlits, S. K.; Yamashita, D.; Kim, M. S.; Anyfrieva, K.; Kawaguchi, R.; Qin, Y.; Burlingame, A.; Oses-Prieto, J. A.; Goldman, S.; Hjelmeland, A.; Nam, D.-H.; Kornblum, H.; Nakano, I.
10.1101/2020.10.12.335091 — cancer biology — Posted on 2020-10-12
2852 Characterizing the spatial signal of environmental DNA in river systems using a community ecology approach
Cantera, I.; Decotte, J.-B.; Dejean, T.; Murienne, J.; Vigouroux, R.; Valentini, A.; Brosse, S.
10.1101/2020.10.11.333047 — ecology — Posted on 2020-10-12
2856 Cryo-EM reveals structural breaks in a patient-derived amyloid fibril from systemic AL amyloidosis
Radamaker, L.; Baur, J. D.; Huhn, S.; Haupt, C.; Hegenbart, U.; Schönland, S.; Bansal, A.; Schmidt, M.; Fändrich, M.
10.1101/2020.10.12.332569 — molecular biology — Posted on 2020-10-12
2857 Human Cytomegalovirus antagonizes activation of Fcγ receptors II and III by distinct and synergizing modes of IgG manipulation
Kolb, P.; Hoffmann, K.; Sievert, A.; Reinhard, H.; Merce-Maldonado, E.; Le-Trilling, V. T. K.; Guetle, D.; Hengel, H.
10.1101/2020.10.12.335539 — microbiology — Posted on 2020-10-12
2858 Rest functional brain maturation during the first year of life
Lemaitre, H.; Auge, P.; Saitovitch, A.; Tacchella, J.-M.; Fillon, L.; Calmon, R.; Levy, R.; Grevent, D.; Brunelle, F.; Boddaert, N.; Zilbovicius, M.
10.1101/760843 — neuroscience — Posted on 2020-10-12
2859 Sex-specific maturational trajectory of endocannabinoid plasticity in the rat prefrontal cortex
Bernabeu, A.; Bara, A.; Manduca, A.; Borsoi, M.; Lassalle, O.; Pelissier-Alicot, A.-L.; MANZONI, O. J.
10.1101/2020.10.09.332965 — neuroscience — Posted on 2020-10-12
2860 Cancer LncRNA Census 2 (CLC2): an enhanced resource reveals clinical features of cancer lncRNAs
Vancura, A.; Lanzos, A.; Bosch, N.; Torres, M.; Hionides Gutierrez, A.; Haefliger, S.; Johnson, R.
10.1101/2020.04.28.066225 — cancer biology — Posted on 2020-10-12
2861 Somatic chromosomal number alterations affecting driver genes inform in-vitro and clinical drug response in high-grade serous ovarian cancer
Correia Martins, F.; Couturier, D.-L.; Santiago, I.; Sauer, C.; Vias, M.; Angelova, M.; Sanders, D.; Piskorz, A.; Hall, J.; Hosking, K.; Amirthanayagam, A.; Cosulich, S.; Carnevalli, L.; Davies, B.; Watkins, T. B. K.; Funingana, G.; Bolton, H.; Haldar, K.; Latimer, J.; Baldwin, P.; Crawford, R.; Eldridge, M.; Basu, B.; Jimenez-Linan, M.; McGranahan, N.; Litchfield, K.; Shah, S.; McNeish, I.; Caldas, C.; Evan, G.; Swanton, C.; Brenton, J. D.
10.1101/2020.10.04.325365 — cancer biology — Posted on 2020-10-12
2864 A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies
Tiu, G. C.; Kerr, C. H.; Forester, C. M.; Krishnarao, P. S.; Rosenblatt, H. D.; Raj, N.; Zhulyn, O.; Bowen, M. E.; Shokat, L.; Attardi, L. D.; Ruggero, D.; Barna, M.
10.1101/2020.06.24.167940 — developmental biology — Posted on 2020-10-12
2865 A red fluorescent protein with improved monomericity enables ratiometric voltage imaging with ASAP3
Kim, B. B.; Wu, H.; Hao, Y. A.; Pan, M.; Chavarha, M.; Westberg, M.; St-Pierre, F.; Wu, J. C.; Lin, M.
10.1101/2020.10.09.328922 — cell biology — Posted on 2020-10-12
2866 Expanded CAG/CTG Repeats Resist Gene Silencing Mediated by Targeted Epigenome Editing
Yang, B.; Borgeaud, A. C.; Aeschbach, L.; Rodriguez-Lima, O.; Ruiz Buendia, G. A.; Cinesi, C.; Baubec, T.; Dion, V.
10.1101/368480 — molecular biology — Posted on 2020-10-12
2867 Direct measurements of mRNA translation kinetics in living cells
Metelev, M.; Volkov, I. L.; Lundin, E.; Gynnå, A. H.; Elf, J.; Johansson, M.
10.1101/2020.10.12.335505 — molecular biology — Posted on 2020-10-12
2869 TWIST1 controls cellular senescence and energy metabolism in mesenchymal stem cells
Voskamp, C.; Anderson, L.; Koevoet, W.; Barnhoorn, S.; Mastroberardino, P. G.; Osch, G. v.; Narcisi, R.
10.1101/2020.10.11.335448 — cell biology — Posted on 2020-10-11
2872 A polymer gel index-matched to water enables diverse applications in fluorescence microscopy
Han, X.; Su, Y.; White, H.; O'Neill, K. M.; Morgan, N. Y.; Christensen, R.; Potarazu, D.; Vishwasrao, H. D.; Xu, S.; Sun, Y.; Huang, S.-y.; Moyle, M. W.; Dai, Q.; Pommier, Y.; Giniger, E.; Albrecht, D. R.; Probst, R.; Shroff, H.
10.1101/2020.10.04.324996 — bioengineering — Posted on 2020-10-11
2873 Expansion of gamma-butyrolactone signaling molecule biosynthesis to phosphotriester natural products
Kudo, Y.; Awakawa, T.; Du, Y.-L.; Jordan, P. A.; Creamer, K. E.; Jensen, P. R.; Linington, R. G.; Ryan, K. S.; Moore, B. S.
10.1101/2020.10.11.335315 — biochemistry — Posted on 2020-10-11
2874 New targets acquired: improving locus recovery from the Angiosperms353 probe set
McLay, T. G.; Birch, J. L.; Gunn, B. F.; Ning, W.; Tate, J. A.; Nauheimer, L.; Joyce, E. M.; Simpson, L.; Weigner, N.; Schmidt-Lebuhn, A. N.; Baker, W. J.; Forest, F.; Jackson, C. J.
10.1101/2020.10.04.325571 — bioinformatics — Posted on 2020-10-11
2876 A single-cell atlas of Plasmodium falciparum transmission through the mosquito
Real, E.; Howick, V.; Dahalan, F.; Witmer, K.; Cudini, J.; Andradi-Brown, C.; Blight, J.; Davidson, M.; Dogga, S. K.; Reid, A. J.; Baum, J.; Lawniczak, M.
10.1101/2020.10.11.333179 — genomics — Posted on 2020-10-11
2878 Adaptive divergence in shoot gravitropism creates intrinsic reproductive isolation in an Australian wildflower
Wilkinson, M. J.; Roda, F.; Walter, G. M.; James, M. E.; Nipper, R.; Walsh, J.; Allen, S. L.; Bernal, D. M.; North, H. L.; Beveridge, C. A.; Ortiz-Barrientos, D.
10.1101/845354 — evolutionary biology — Posted on 2020-10-11
2881 A bacterial inflammation sensor regulates c-di-GMP signaling, adhesion, and biofilm formation.
Perkins, A.; Tudorica, D. A.; Teixeira, R. D.; Schirmer, T.; Zumwalt, L.; Ogba, O. M.; Cassidy, C. K.; Stansfeld, P. J.; Guillemin, K.
10.1101/2020.10.11.335190 — microbiology — Posted on 2020-10-11
2883 BOLD response to multiple grip forces in MS: going beyond the main effect of movement in BA 4a and BA 4p
Alahmadi, A. A. S.; Pardini, M.; Samson, R.; D'Angelo, E. U.; Friston, K.; Toosy, A.; Gandini Wheeler-Kingshott, C. A. M.
10.1101/2020.10.11.334599 — neuroscience — Posted on 2020-10-11
2885 Network potential identifies therapeutic miRNA cocktails in Ewings Sarcoma
Weaver, D. T.; Pishas, K. I.; Williamson, D.; Scarborough, J.; Lessnick, S. L.; Dhawan, A.; Scott, J. G.
10.1101/854695 — systems biology — Posted on 2020-10-11
2886 A synthetic RNA-based biosensor for fructose-1,6-bisphosphate that reports glycolytic flux
Ortega, A. D.; Takhaveev, V.; Bonsing-Vedelaar, S.; Long, Y.; Mestre-Farras, N.; Incarnato, D.; Ersoy, F.; Olsen, L. F.; Mayer, G.; Heinemann, M.
10.1101/2020.10.11.335109 — synthetic biology — Posted on 2020-10-11
2887 DRP1 IS REQUIRED FOR AGRP NEURONAL ACTIVITY AND FEEDING
Jin, S.; Yoon, N. A.; Liu, Z.-W.; Horvath, T.; Kim, J. D.; Diano, S.
10.1101/2020.10.11.335224 — physiology — Posted on 2020-10-11
2889 Structure Specific Neuro-toxicity of α-Synuclein Oligomer
Mondal, A.; Dolui, S.; Dhabal, S.; Bhattacharjee, A.; Maiti, N. C.
10.1101/2020.10.11.334979 — biophysics — Posted on 2020-10-11
2891 Genotype-free individual genome reconstruction of Multiparental Population Models by RNA sequencing data
Choi, K.; He, H.; Gatti, D. M.; Philip, V. M.; Raghupathy, N.; Munger, S. C.; Chesler, E. J.; Churchill, G. A.
10.1101/2020.10.11.335323 — bioinformatics — Posted on 2020-10-11
2894 A parental transcriptional response to microsporidia infection induces inherited immunity in offspring
Willis, A. R.; Zhao, W.; Sukhdeo, R.; Wadi, L.; Tamim El Jarkass, H.; Claycomb, J. W.; Reinke, A. W.
10.1101/2020.10.11.335117 — microbiology — Posted on 2020-10-11
2896 The human brain vasculature shows a distinct expression pattern of SARS-CoV-2 entry factors
Ghobrial, M.; Charish, J.; Takada, S.; Valiante, T.; Monnier, P.; Radovanovic, I.; Bader, G.; Waelchli, T.
10.1101/2020.10.10.334664 — neuroscience — Posted on 2020-10-11
2901 The landscape of antibody binding to SARS-CoV-2
Heffron, A. S.; McIlwain, S. J.; Baker, D. A.; Amjadi, M. F.; Khullar, S.; Sethi, A. K.; Shelef, M. A.; O'Connor, D. H.; Ong, I. M.
10.1101/2020.10.10.334292 — immunology — Posted on 2020-10-11
2902 Single-dose intranasal administration of AdCOVID elicits systemic and mucosal immunity against SARS-CoV-2 in mice
King, R. G.; Silva-Sanchez, A.; Peel, J. N.; Botta, D.; Meza-Perez, S.; Allie, R.; Schultz, M. D.; Liu, M.; Bradley, J. E.; Qiu, S.; Yang, G.; Zhou, F.; Zumaquero, E.; Simpler, T. S.; Mousseau, B.; Killian, J. T.; Dean, B.; Shang, Q.; Tipper, J. L.; Risley, C.; Harrod, K. S.; Feng, R.; Lee, Y.; Shiberu, B.; Krishnan, V.; Peguillet, I.; Zhang, J.; Green, T.; Randall, T. D.; Georges, B.; Lund, F. E.; Roberts, S.
10.1101/2020.10.10.331348 — immunology — Posted on 2020-10-11
2903 Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α
Mann, S.; Hadad, N.; Nelson, M.; Rothman, A.; Sathiaseelan, R.; Ali-Mondal, S.; Agbaga, M.-P.; Unnikrishnan, A.; Malayannan, S.; Hawse, J.; Huffmam, D.; Freeman, W. M.; Stout, M. B.
10.1101/2020.06.02.130674 — physiology — Posted on 2020-10-11
2904 Evolutionarily Driven Domain Swap Alters Sigma Factor Dependence in Bacterial Signaling System
Garber, M. E.; Frank, V.; Kazakov, A. E.; Zhang, H.; Incha, M. R.; Rajeev, L.; Keasling, J. D.; Mukhopadhyay, A.
10.1101/2020.09.30.321588 — evolutionary biology — Posted on 2020-10-11
2906 TMEM41B is a pan-flavivirus host factor
Hoffmann, H.- H.; Schneider, W. M.; Rozen-Gagnon, K.; Miles, L. A.; Schuster, F.; Razooky, B.; Jacobson, E.; Wu, X.; Yi, S.; Rudin, C. M.; MacDonald, M. R.; McMullan, L. K.; Poirier, J. T.; Rice, C. M.
10.1101/2020.10.09.334128 — molecular biology — Posted on 2020-10-11
2907 Distinct higher-order representations of natural sounds in human and ferret auditory cortex
Landemard, A.; Bimbard, C.; Demene, C.; Shamma, S.; Norman-Haignere, S. V.; Boubenec, Y.
10.1101/2020.09.30.321695 — neuroscience — Posted on 2020-10-11
2912 Native structure of flagellar MS ring is formed by 34 subunits with 23-fold and 11-fold subsymmetries
Kawamoto, A.; Miyata, T.; Makino, F.; Kinoshita, M.; Minamino, T.; Imada, K.; Kato, T.; Namba, K.
10.1101/2020.10.11.334888 — microbiology — Posted on 2020-10-11
2913 3D reconstruction of genomic regions from sparse interaction data
Mendieta-Esteban, J.; Di Stefano, M.; Castillo, D.; Farabella, I.; Marti-Renom, M. A.
10.1101/2020.10.11.334847 — bioinformatics — Posted on 2020-10-11
2914 Brain aging-dependent glioma traits reversible by NAD+/BDNF-mediated neuronal reactivation
Yamashita, D.; Flanary, V. L.; Munk, R. B.; Sonomura, K.; Ozaki, S.; Kawaguchi, R.; Suehiro, S.; Bastola, S.; Pavlyukov, M. S.; Yamaguchi, S.; Nakano, M. A.; Kunieda, T.; Hambardzumyan, D.; Kondo, T.; Kornblum, H.; Crossman, D.; Hackney, J. R.; Sato, T.-a.; Gorospe, M.; Nakano, I.
10.1101/2020.10.10.334748 — cancer biology — Posted on 2020-10-11
2916 Flexible and transparent silver nanowire structures for multifunctional electrical and optical biointerfacing
Chen, Z.; Boyajian, N.; Lin, Z.; Yin, R. T.; Obaid, S. N.; Tian, J.; Brennan, J. A.; Chen, S. W.; Miniovich, A. N.; Lin, L.; Qi, Y.; Liu, X.; Efimov, I. R.; Lu, L.
10.1101/2020.10.10.334755 — bioengineering — Posted on 2020-10-11
2920 Learning Patterns of the Ageing Brain in MRI using Deep Convolutional Networks
Dinsdale, N. K.; Bluemke, E.; Smith, S. M.; Arya, Z.; Vidaurre, D.; Jenkinson, M.; Namburete, A. I. L.
10.1101/2020.08.17.253732 — neuroscience — Posted on 2020-10-11
2924 Signal bias at glucagon family receptors: rationale and downstream impacts
Jones, B.; McGlone, E. R.; Fang, Z.; Pickford, P.; Correa, I. R.; Oishi, A.; Jockers, R.; Inoue, A.; Kumar, S.; Görlitz, F.; Dunsby, C.; French, P. M.; Rutter, G. A.; Tan, T. M.; Tomas, A.; Bloom, S. R.
10.1101/2020.04.26.062372 — pharmacology and toxicology — Posted on 2020-10-11
2925 Fibrous caps in atherosclerosis form by Notch-dependent mechanisms common to arterial media development
Martos Rodriguez, C. J.; Albarran-Juarez, J.; Morales Cano, D.; Caballero, A.; MacGrogan, D.; de la Pompa, J. L.; Carramolino, L.; Bentzon, J. F.
10.1101/2020.09.28.316984 — pathology — Posted on 2020-10-11
2928 A 180 My-old female-specific genome region in sturgeon reveals the oldest known vertebrate sex determining system with undifferentiated sex chromosomes
Kuhl, H.; Guiguen, Y.; Hoehne, C.; Keuz, E.; Klopp, C.; Du, K.; Lopez-Roques, C.; Santidrian Yebra-Pimentel, E.; Ciorpac, M.; Gessner, J.; Holostenco, D.; Kleiner, W.; Kohlmann, K.; Lamatsch, D.; Prokopov, D.; Bestin, A.; Bonpunt, E.; Debeuf, B.; Haffay, P.; Morvezen, R.; Patrice, P.; Suciu, R.; Dirks, R.; Wuertz, S.; Kloas, W.; Schartl, M.; Stoeck, M.
10.1101/2020.10.10.334367 — evolutionary biology — Posted on 2020-10-10
2929 Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress
Jobava, R.; Mao, Y.; Guan, B.-J.; Krokowski, D.; Shu, E.; Chukwurah, E.; Wu, J.; Gao, Z.; Zagore, L. L.; Merrick, W. C.; Zhang, Y.; Qi, X.; Jankowsky, E.; Topisirovic, I.; Licatalosi, D. D.; Qian, S.-B.; Hatzoglou, M.
10.1101/2020.10.10.334375 — molecular biology — Posted on 2020-10-10
2930 Calcium signaling through a Transient Receptor Channel is important for Toxoplasma gondii growth
Marquez-Nogueras, K. M.; Chasen, N. M.; Hortua Triana, M. A.; Kuo, I. Y.; Moreno, S. N. J.
10.1101/2020.10.09.332593 — microbiology — Posted on 2020-10-10
2933 Olig3 acts as a master regulator of cerebellar development
Lowenstein, E. D.; Rusanova, A.; Stelzer, J.; Hernaiz-Llorens, M.; Schroer, A. E.; Bladt, F.; Isik, E. G.; Jia, S.; Tarabykin, V.; Hernandez-Miranda, L. R.
10.1101/2020.10.10.334615 — neuroscience — Posted on 2020-10-10
2939 Innate behavior sequence progression by peptide-mediated interorgan crosstalk
Heredia, F.; Volonte, Y.; Pereirinha, J.; Fernandez-Acosta, M.; Casimiro, A. P.; Belem, C. G.; Viegas, F.; Tanaka, K.; Arana, M.; Cardoso, G. A.; Macedo, A.; Kotowicz, M.; Prado Spalm, F. H.; Dibo, M.; Monfardini, R. D.; Torres, T. T.; Mendes, C. S.; Garelli, A.; Gontijo, A. M.
10.1101/2020.10.10.334540 — animal behavior and cognition — Posted on 2020-10-10
2940 Aberrant replication licensing drives Copy Number Gains across species
Nathanailidou, P.; Petropoulos, M.; Maxouri, S.; Kasselimi, E.; Symeonidou, I. E.; Preza, O.; Spiliopoulou-Sdougkou, I.; Benes, V.; Taraviras, S.; Lygerou, Z.
10.1101/2020.10.10.334516 — molecular biology — Posted on 2020-10-10
2941 Topographical biomaterials instruct bacterial surface attachment and the in vivo host-pathogen response
Romero, M.; Luckett, J.; Figueredo, G.; Carabelli, A.; Carlier, A.; Vasilevich, A. S.; Vermeulen, S.; Scurr, D.; Hook, A.; Dubern, J.-F.; Winkler, D. A.; Ghaemmaghami, A. M.; de Boer, J.; Alexander, M. R.; Williams, P.
10.1101/2020.10.10.328146 — microbiology — Posted on 2020-10-10
2943 Culture influences audiovisual emotion perception in early sensory areas
Tanaka, A.; Takagi, S.; Harada, T.; Huis In 't Veld, E.; de Gelder, B.; Hamano, Y.; Tabei, K.-i.; Sadato, N.
10.1101/2020.10.10.332437 — neuroscience — Posted on 2020-10-10
2946 The Synergism Between DHODH Inhibitors and Dipyridamole Leads to Synthetic Lethality in Acute Myeloid Leukemia
Gaidano, V.; Houshmand, M.; Vitale, N.; Carra, G.; Morotti, A.; Tenace, V.; Rapelli, S.; Sainas, S.; Pippione, A.; Giorgis, M.; Boschi, D.; Lolli, M. L.; Cignetti, A.; Saglio, G.; Circosta, P.
10.1101/2020.10.10.334631 — cancer biology — Posted on 2020-10-10
2950 Comprehensive identification of somatic nucleotide variants in human brain tissue
Wang, Y.; Bae, T.; Thorpe, J.; Sherman, M. A.; Jones, A. G.; Cho, S.; Daily, K.; Dou, Y.; Ganz, J.; Galor, A.; Lobon, I.; Pattni, R.; Rosenbluh, C.; Tomasi, S.; Tomasini, L.; Yang, X.; Zhou, B.; Akbarian, S.; Ball, L. L.; Bizzotto, S.; Emery, S. B.; Doan, R.; Fasching, L.; Jang, Y.; Juan, D.; Lizano, E.; Moldovan, J. B.; Narurkar, R.; Oetjens, M. T.; Sekar, S.; Shin, J. H.; Soriano, E.; Straub, R. E.; Zhou, W.; Chess, A.; Gleeson, J. G.; Marques-Bonet, T.; Park, P. J.; Peters, M. A.; Pevsner, J.; Walsh, C. A.; Weinberger, D. R.; Brain Somatic Mosaicism Network, ; Vaccarino, F. M.; Moran, J. V
10.1101/2020.10.10.332213 — genomics — Posted on 2020-10-10
2952 Automated tracking of S. pombe spindle elongation dynamics
Uzsoy, A. S. M.; Zareiesfandabadi, P.; Jennings, J.; Kemper, A. F.; Elting, M. W.
10.1101/2020.10.09.333765 — cell biology — Posted on 2020-10-10
2956 Temperature-dependence of metabolic rate in tropical and temperate aquatic insects: support for the Climate Variability Hypothesis in mayflies but not stoneflies.
Shah, A. A.; Woods, H. A.; Havird, J. C.; Encalada, E. C.; Flecker, A. S.; Funk, W. C.; Guayasamin, J. M.; Kondratieff, B. K.; Poff, N. L.; Thomas, S. A.; Zamudio, K. R.; Ghalambor, C. K.
10.1101/2019.12.25.888578 — ecology — Posted on 2020-10-10
2957 A red fluorescent protein with improved monomericity enables ratiometric voltage imaging with ASAP3
Kim, B. B.; Wu, H.; Hao, Y. A.; Pan, M.; Chavarha, M.; Westberg, M.; St-Pierre, F.; Wu, J. C.; Lin, M.
10.1101/2020.10.09.328922 — cell biology — Posted on 2020-10-10
2958 AMP-activated protein kinase is a key regulator of retinal vascular permeability
Dragoni, S.; Caridi, B.; Karatsai, E.; Burgoyne, T.; Sarker, M. H.; Turowski, P.
10.1101/802033 — neuroscience — Posted on 2020-10-10
2959 Soluble Spike DNA vaccine provides long-term protective immunity against SAR-CoV-2 in mice and nonhuman primates
Seo, Y. B.; Suh, Y. S.; Ryu, J. I.; Jang, H.; Oh, H.; Koo, B.-S.; Seo, S.-H.; Hong, J. J.; Song, M.; Kim, S.-J.; Sung, Y. C.
10.1101/2020.10.09.334136 — immunology — Posted on 2020-10-10
2960 Three-dimensional FIB-SEM reconstruction of microtubule-organelle interaction in whole primary mouse beta cells
Mueller, A.; Schmidt, D.; Xu, C. S.; Pang, S.; D'Costa, J. V.; Kretschmar, S.; Muenster, C.; Kurth, T.; Jug, F.; Weigert, M.; Hess, H. F.; Solimena, M.
10.1101/2020.10.07.329268 — cell biology — Posted on 2020-10-10
2961 Kidney injury molecule-1 is a potential receptor for SARS-CoV-2
Yang, C.; Zhang, Y.; Chen, H.; Chen, Y.; Yang, D.; Shen, Z.; Wang, X.; Liu, X.; Xiong, M.; Huang, K.
10.1101/2020.10.09.334052 — cell biology — Posted on 2020-10-10
2962 Spatial modulation of visual signals arises in cortex with active navigation
Diamanti, E. M.; Bai Reddy, C.; Schroeder, S.; Muzzu, T.; Harris, K. D.; Saleem, A. B.; Carandini, M.
10.1101/832915 — neuroscience — Posted on 2020-10-10
2963 BPIFB1 loss alters airway mucus properties and diminishes mucociliary clearance.
Donoghue, L. J.; Markovetz, M. R.; Morrison, C. B.; McFadden, K. M.; Rogers, T. D.; Button, B.; Ehre, C.; Hill, D. B.; Grubb, B. R.; Kelada, S. N. P.
10.1101/2020.06.17.155846 — physiology — Posted on 2020-10-10
2969 Cathepsin K maintains the number of lymphocytes in vivo
Hausinger, R. I.; Hackl, M.; Jardon Alvarez, A.; Kehr, M.; Romero Marquez, S.; Hettler, F.; Kehr, C.; Grziwok, S.; Schreck, C.; Peschel, C.; Istvanffy, R.; Oostendorp, R.
10.1101/2020.03.04.977496 — cell biology — Posted on 2020-10-10
2971 Fetal innate immunity contributes to the induction of atypical behaviors in a mouse model of maternal immune activation
Nichols, E. K.; Chuang, H.-C.; Davis, M. T.; Geiger, K. M.; Li, R. Z.; Arnold, M. L.; Lin, P. M.; Misra, R.; Coscoy, L.; Saijo, K.
10.1101/2020.10.09.333815 — neuroscience — Posted on 2020-10-10
2972 Investigating the interaction between white matter and brain state on tDCS-induced changes in brain network activity
Kurtin, D. L.; Violante, I. R.; Zimmerman, K.; Leech, R.; Hampshire, A.; Patel, M. C.; Carmichael, D. W.; Sharp, D. J.; Li, L. M.
10.1101/2020.10.09.332742 — neuroscience — Posted on 2020-10-10
2973 Clinical connectome fingerprints of cognitive decline
Sorrentino, P.; Rucco, R.; Lardone, A.; Liparoti, M.; Troisi Lopez, E.; Cavaliere, C.; Soricelli, A.; Jirsa, V.; Sorrentino, G.; Amico, E.
10.1101/2020.10.09.332635 — neuroscience — Posted on 2020-10-10
2975 Smaller Hippocampal Volume among Black and Latinx Youth Living in High-Stigma Contexts
Hatzenbuehler, M. L.; Weissman, D. G.; McKetta, S.; Lattanner, M. R.; Ford, J. V.; Barch, D. M.; McLaughlin, K. A.
10.1101/2020.10.09.333328 — neuroscience — Posted on 2020-10-10
2978 Multiplane Mesoscope reveals distinct cortical interactions following expectation violations
Orlova, N.; Tsyboulski, D.; Najafi, F.; Seid, S.; Kivikas, S.; Kato, I.; Griffin, F.; Leon, A.; L'Heureux, Q.; North, K.; Swapp, J.; Nayan, C.; Hancock, N.; Ahmed, R.; Gelfand, E.; Cho, A.; Mace, K.; Howard, R.; Casal, L.; Lambert, S.; Lee, E. K.; Caldejon, S.; Waughman, X.; Williford, A.; Garrett, M.; Ollerenshaw, D.; Olsen, S. R.; Groblewski, P.; Lecoq, J.; Saggau, P.
10.1101/2020.10.06.328294 — neuroscience — Posted on 2020-10-10
2982 Accelerated erythrocyte senescence causes dose-limiting anemia of antimalarial enolase inhibitors
Jezewski, A. J.; Lin, Y.-H.; Reisz, J. A.; Culp-Hill, R.; Barekatain, Y.; Yan, V. C.; D'Alessandro, A.; Muller, F. L.; Odom John, A. R.
10.1101/2020.10.09.331728 — pharmacology and toxicology — Posted on 2020-10-10
2984 HectoSTAR microLED optoelectrodes for large-scale, high-precision in invo opto-electrophysiology
Kim, K.; Vöröslakos, M.; Fernandez-Ruiz, A.; Parizi, S. S.; Ko, E.; Hendrix, B.; Seymour, J. P.; Wise, K. D.; Buzsaki, G.; Yoon, E.
10.1101/2020.10.09.334227 — bioengineering — Posted on 2020-10-10
2985 Phenotypic and molecular evolution across 10,000 generations in laboratory budding yeast populations
Johnson, M. S.; Gopalakrishnan, S.; Goyal, J.; Dillingham, M. E.; Bakerlee, C. W.; Humphrey, P. T.; Jagdish, T.; Jerison, E. R.; Kosheleva, K.; Lawrence, K. R.; Min, J.; Moulana, A.; Phillips, A. M.; Piper, J. C.; Purkanti, R.; Rego-Costa, A.; McDonald, M. J.; Nguyen Ba, A. N.; Desai, M. M.
10.1101/2020.10.09.330191 — evolutionary biology — Posted on 2020-10-10
2988 A red fluorescent protein with improved monomericity enables ratiometric voltage imaging with ASAP3
Kim, B. B.; Wu, H.; Hao, Y. A.; Pan, M.; Chavarha, M.; Westberg, M.; St-Pierre, F.; Wu, J. C.; Lin, M.
10.1101/2020.10.09.328922 — cell biology — Posted on 2020-10-10
2992 Integrative Analysis the characterization of peroxiredoxins in pan-cancer
Gao, L.; Meng, J.; Yue, C.; Wu, X.; Su, Q.; Wu, H.; Zhang, Z.; Yu, Q.; Gao, S.; Fan, S.; Zuo, L.
10.1101/2020.10.09.334086 — cancer biology — Posted on 2020-10-10
2993 Restructuring of the Immune Contexture Improves Checkpoint Blockade Efficacy in Murine Lung Cancer
Ebelt, N. D.; Zuniga, E.; Marzagalli, M.; Zamloot, V.; Blazar, B. R.; Salgia, R.; Manuel, E. R.
10.1101/2020.10.09.332387 — cancer biology — Posted on 2020-10-10
2994 Expanding the Galaxy's reference data
VijayKrishna, N.; Joshi, J.; Coraor, N.; Hillman-Jackson, J.; Bouvier, D.; van den Beek, M.; Eguinoa, I.; Coppens, F.; Golitsynskiy, S.; Stolarczyk, M.; Sheffield, N. C.; Gladman, S.; Cuccuru, G.; Grüning, B.; Soranzo, N.; Rasche, H.; Langhorst, B. W.; Bernt, M.; Fornika, D.; de Lima Morais, D. A.; Barrette, M.; van Heusden, P.; Petrillo, M.; Puertas-Gallardo, A.; Patak, A.; Hotz, H.-R.; Blankenberg, D.
10.1101/2020.10.09.327114 — bioinformatics — Posted on 2020-10-10
2997 piRPheno: a manually curated database to prioritize and analyze human disease related piRNAs
Zhang, W.; Wu, S.; Zhang, H.; Guan, W.; Zeng, B.; Wei, Y.; Chan, G. C.-F.; Li, W.; Zhang, W.
10.1101/2020.10.09.334219 — bioinformatics — Posted on 2020-10-10
3002 A Chinese hamster transcription start site atlas that enables targeted editing of CHO cells
Shamie, I. S.; Duttke, S. H.; la Cour Karottki, K. J.; Han, C. Z.; Hansen, A. H.; Hefzi, H.; Xiong, K.; Li, S.; Roth, S.; Tao, J.; Lee, G. M.; Glass, C. K.; Kildegaard, H. F.; Benner, C.; Lewis, N. E.
10.1101/2020.10.09.334045 — genomics — Posted on 2020-10-10
3008 Evolutionary diversification of tiny ocean predators
Latorre, F.; Deutschmann, I. M.; Labarre, A.; Obiol, A.; Krabberod, A. K.; Pelletier, E.; Sieracki, M. E.; Cruaud, C.; Jaillon, O.; Massana, R.; Logares, R.
10.1101/2020.10.09.333062 — ecology — Posted on 2020-10-10
3010 Misoprostol Treatment Prevents Hypoxia-Induced Cardiac Dysfunction, Aberrant Cardiomyocyte Mitochondrial Dynamics and Permeability Transition Through Bnip3 Phosphorylation
Martens, M. D.; Seshadri, N.; Nguyen, L.; Chapman, D.; Hensen, E. S.; Xiang, B.; Mendoza, A.; Rattan, S.; Gibson, S. B.; Saleem, A. D.; Hatch, G. M.; Doucette, C. A.; Karch, J. M.; Dolinsky, V. W.; Dixon, I. M.; West, A. R.; Rampitsch, C.; Gordon, J. W.
10.1101/2020.10.09.333666 — cell biology — Posted on 2020-10-10
3011 mTORC2 combats cellular stress and potentiates immunity during viral infection
Suryawanshi, R. K.; Patil, C. D.; Agelidis, A.; Koganti, R.; Ames, J. M.; Koujah, L.; Yadavalli, T.; Madavaraju, K.; Shantz, L. M.; Shukla, D.
10.1101/2020.10.09.333500 — cell biology — Posted on 2020-10-10
3012 TMEM41B is a pan-flavivirus host factor
Hoffmann, H.- H.; Schneider, W. M.; Rozen-Gagnon, K.; Miles, L. A.; Schuster, F.; Razooky, B.; Jacobson, E.; Wu, X.; Yi, S.; Rudin, C. M.; MacDonald, M. R.; McMullan, L. K.; Poirier, J. T.; Rice, C. M.
10.1101/2020.10.09.334128 — molecular biology — Posted on 2020-10-10
3015 Estimating intra-axonal axial diffusivity in the presence of fibre orientation dispersion
Howard, A. F.; Lange, F. J.; Mollink, J.; Cottaar, M.; Drakesmith, M.; Rudrapatna, S. U.; Jones, D. K.; Miller, K. L.; Jbabdi, S.
10.1101/2020.10.09.332700 — neuroscience — Posted on 2020-10-10
3018 Sex-specific maturational trajectory of endocannabinoid plasticity in the rat prefrontal cortex
Bernabeu, A.; Bara, A.; Manduca, A.; Borsoi, M.; Lassalle, O.; Pelissier-Alicot, A.-L.; MANZONI, O. J.
10.1101/2020.10.09.332965 — neuroscience — Posted on 2020-10-10
3020 Age-related differences in network structure and dynamic synchrony of cognitive control
Hinault, T. T.; Mijalkov, M.; Pereira, J.; Volpe, G.; Bakker, A.; Courtney, S. M.
10.1101/2020.10.09.333567 — neuroscience — Posted on 2020-10-10
3028 Functional diversity of PFKFB3 splice variants in glioblastomas
Heydasch, U.; Kessler, R.; Warnke, J.-P.; Eschrich, K.; Scholz, N.; Bigl, M.
10.1101/2020.10.09.332817 — cancer biology — Posted on 2020-10-09
3030 Bacterial precursors and unsaturated long-chain fatty acids are biomarkers of North-Atlantic demosponges
de Kluijver, A.; Nierop, K. G. J.; Morganti, T. M.; Bart, M. C.; Slaby, B. M.; Hanz, U.; de Goeij, J. M.; Mienis, F.; Middelburg, J. J.
10.1101/2020.10.09.332833 — biochemistry — Posted on 2020-10-09
3031 The transcriptome of regenerating zebrafish scales identifies genes involved in human bone disease
Bergen, D. J. M.; Tong, Q.; Shukla, A.; Newham, E.; Zethof, J.; Lundberg, M.; Ryan, R.; Youlten, S. E.; Kague, E.; Zeggini, E.; Croucher, P. I.; Flik, G.; Richardson, R. J.; Kemp, J. P.; Hammond, C. L.; Metz, J. R.
10.1101/2020.10.08.331561 — genetics — Posted on 2020-10-09
3032 Complete mitogenome of endemic Plum-headed parakeet Psittacula cyanocephala - characterization and phylogenetic analysis
DEY, P.; Sharma, S. K.; Sarkar, I.; Ray, S. D.; Pramod, P.; Kochiganti, V. H. S.; Quadros, G.; Singh, R.; SINGH, R. P.
10.1101/2020.10.09.332866 — evolutionary biology — Posted on 2020-10-09
3034 Whole Genome and Embryo Transcriptome Analysis of Vertebrate Identifies nxhl Controlling Angiogenesis by Targeting VE-PTP
LUo, H.; Zhang, Y.; Ji, C.; Zhao, Y.; Peng, J.; Chen, X.; Huang, Y.; Liu, Q.; He, P.; Feng, P.; Yang, C.; Wei, P.; Yu, H.; Zheng, H.; Lin, Y.; Chen, X.
10.1101/804609 — developmental biology — Posted on 2020-10-09
3036 Novel mechanisms of type IV pilus regulation in Acinetobacter baylyi
Ellison, C. K.; Dalia, T. N.; Klancher, C. A.; Shaevitz, J. W.; Gitai, Z.; Dalia, A. B.
10.1101/2020.09.28.317149 — microbiology — Posted on 2020-10-09
3037 SARS-CoV-2 infection induces mixed M1/M2 phenotype in circulating monocytes and alterations in both dendritic cell and monocyte subsets
Matic, S.; Popovic, S.; Djurdjevic, P.; Todorovic, D.; Djordjevic, N.; Mijailovic, Z.; Sazdanovic, P.; Milovanovic, D.; Ruzic Zecevic, D.; Petrovic, M.; Sazdanovic, M.; Zornic, N.; Vukicevic, V.; Petrovic, I.; Matic, S.; Karic Vukicevic, M.; Baskic, D.
10.1101/2020.10.09.332858 — immunology — Posted on 2020-10-09
3038 Cross-Linking of T cell to B cell lymphoma by the T cell bispecific antibody CD20-TCB induces IFNγ/CXCL10-dependent peripheral T cell recruitment in humanized murine model.
Cremasco, F.; Menietti, E.; Speziale, D.; Sam, J.; Sammicheli, S.; Richard, M.; Varol, A.; Klein, C.; Umana, P.; Bacac, M.; Colombetti, S.; Perro, M.
10.1101/2020.10.09.332874 — immunology — Posted on 2020-10-09
3040 Association between neurofibromatosis type 1 and cerebrovascular diseases in children: a systematic review
Barreto-Duarte, B.; Andrade-Gomes, F. H.; Arriaga, M. B.; Araujo-Pereira, M.; Cubillos-Angulo, J. M.; Andrade, B. B.
10.1101/2020.10.09.332841 — neuroscience — Posted on 2020-10-09
3043 Constricted migration is associated with stable 3D genome structure differences in melanoma cells
Golloshi, R.; Freeman, T. F.; Das, P.; Raines, T. I.; San Martin, R.; Playter, C.; Thurston, D. M.; McCord, R. P.
10.1101/856583 — systems biology — Posted on 2020-10-09
3044 Improving Deconvolution Methods in Biology through Open Innovation Competitions: An Application to the Connectivity Map
Blasco, A.; Natoli, T.; Endres, M. G.; Sergeev, R. A.; Randazzo, S.; Paik, J. H.; Macaluso, N. M.; Narayan, R.; Lu, X.; Peck, D.; Lakhani, K. R.; Subramanian, A.
10.1101/2020.01.10.897363 — bioinformatics — Posted on 2020-10-09
3047 Atypical molecular basis for drug resistance to mitochondrial function inhibitors in Plasmodium falciparum
Painter, H. J.; Morrisey, J. M.; Mather, M. W.; Orchard, L. M.; Luck, C.; Smilkstein, M. J.; Riscoe, M. K.; Vaidya, A. B.; Llinas, M.
10.1101/2020.10.08.330241 — microbiology — Posted on 2020-10-09
3048 First report of Infectious Spleen and Kidney Necrosis Virus in Nile tilapia in Brazil.
Figueiredo, H. C. P.; Tavares, G. C.; Dorella, F. A.; Rosa, J. C. C.; Marcelino, S. A. C.; Pierezan, F. P.
10.1101/2020.10.08.331991 — microbiology — Posted on 2020-10-09
3049 A universal reading network and its modulation by writing system and reading ability in French and Chinese children
Feng, X.; Altarelli, I.; Monzalvo, K.; Ding, G.; Ramus, F.; Shu, H.; Dehaene, S.; Meng, X.; Dehaene-Lambertz, G.
10.1101/834945 — neuroscience — Posted on 2020-10-09
3051 Face neurons in human visual cortex
Decramer, T.; Premereur, E.; Zhu, Q.; Van Paesschen, W.; van Loon, J.; Vanduffel, W.; Taubert, J.; Janssen, P.; Theys, T.
10.1101/2020.10.09.328609 — neuroscience — Posted on 2020-10-09
3052 Inferring Monosynaptic Connectivity Across Brain Structures In-Vivo
Liew, Y. J.; Pala, A.; Whitmire, C. J.; Stoy, W. A.; Forest, C. R.; Stanley, G. B.
10.1101/2020.10.09.333930 — neuroscience — Posted on 2020-10-09
3053 Music-selective neural populations arise without musical training
Boebinger, D. L.; Norman-Haignere, S. V.; McDermott, J. H.; Kanwisher, N.
10.1101/2020.01.10.902189 — neuroscience — Posted on 2020-10-09
3054 Piezo2 mediates ultrasonic hearing via cochlear outer hair cells in mice
Li, J.; Liu, S.; Song, C.; Hu, Q.; Zhao, Z.; Deng, T.; Zou, L.; Wang, S.; Chen, J.; Liu, L.; Hou, H.; Yuan, K.; Zheng, H.; Liu, Z.; Chen, X.; Sun, W.; Xiao, B.; Xiong, W.
10.1101/2020.10.09.332643 — neuroscience — Posted on 2020-10-09
3056 The lexical categorization model: A computational model of left-ventral occipito-temporal cortex activation in visual word recognition
Gagl, B.; Richlan, F.; Ludersdorfer, P.; Sassenhagen, J.; Eisenhauer, S.; Gregorova, K.; Fiebach, C. J.
10.1101/085332 — neuroscience — Posted on 2020-10-09
3059 High contrast probe cleavage detection on porous silicon biosensors via quantum dot labeled DNA probes
Dubrovsky, M.; Layouni, R.; Bao, M.; Chung, H.; Du, K.; Boriskina, S. V.; Weiss, S. M.; Vermeulen, D.
10.1101/2020.10.07.330589 — bioengineering — Posted on 2020-10-09
3060 Tendon and Motor Phenotypes in the Crtap-/- Mouse Model of Recessive Osteogenesis Imperfecta
Grol, M. W.; Haelterman, N. A.; Lim, J.; Munivez, E. M.; Archer, M.; Hudson, D.; Tufa, S. F.; Keene, D. R.; Lei, K.; Park, D.; Eyre, D.; Lee, B. H.
10.1101/2020.04.21.048488 — genetics — Posted on 2020-10-09
3062 Gpr125 identifies myoepithelial progenitors at tips of lacrimal ducts and is essential for tear film.
Spina, E.; Handlin, R.; Simundza, J.; Incassati, A.; Faiq, M.; Sainulabdeen, A.; Chan, K. C.; Cowin, P.
10.1101/2020.09.15.296749 — developmental biology — Posted on 2020-10-09
3065 Integration of prophages into CRISPR loci remodels viral immunity in Streptococcus pyogenes
Varble, A.; Campisi, E.; Euler, C. W.; Fyodorova, J.; Rostol, J.; Fischetti, V. A.; Marraffini, L. A.
10.1101/2020.10.09.333658 — microbiology — Posted on 2020-10-09
3067 The neural architecture of language: Integrative reverse-engineering converges on a model for predictive processing
Schrimpf, M.; Blank, I. A.; Tuckute, G.; Kauf, C.; Hosseini, E. A.; KANWISHER, N. G.; Tenenbaum, J. B.; Fedorenko, E.
10.1101/2020.06.26.174482 — neuroscience — Posted on 2020-10-09
3069 Standardized and reproducible measurement of decision-making in mice
The International Brain Laboratory, ; Aguillon, V.; Angelaki, D.; Bayer, H. M.; Bonacchi, N.; Carandini, M.; Cazettes, F.; Churchland, A. K.; Chapuis, G.; Dan, Y.; Dewitt, E.; Faulkner, M.; Hamish, F.; Haetzel, L.; Hausser, M.; Hofer, S.; Hu, F.; Khanal, A.; Krasniak, C.; Laranjeira, I.; Mainen, Z.; Meijer, G.; Miska, N.; Mrsic-Flogel, T.; Noel, J.-P.; Pan Vazquez, A.; Sanders, J.; Socha, K.; Terry, R.; Urai, A.; Vergara, H. M.; Wells, M.; Wilson, C.; Witten, I.; Wool, L.; Zador, A.
10.1101/2020.01.17.909838 — neuroscience — Posted on 2020-10-09
3070 Evolutionary and functional genomics of DNA methylation in maize domestication and improvement
Xu, G.; Lyu, J.; Li, Q.; Liu, H.; Wang, D.; Zhang, M.; Springer, N. M.; Ross-Ibarra, J.; Yang, J.
10.1101/2020.03.13.991117 — plant biology — Posted on 2020-10-09
3071 Overcoming barriers to the registration of new varieties
Yang, C. J.; Russell, J.; Ramsay, L.; Thomas, W.; Powell, W.; Mackay, I.
10.1101/2020.10.08.331892 — genetics — Posted on 2020-10-09
3072 Conserved epigenetic regulatory logic infers genes governing cell identity
Shim, W. J.; Sinniah, E.; Xu, J.; Vitrinel, B.; Alexanian, M.; Andreoletti, G.; Shen, S.; Sun, Y.; Balderson, B.; Boix, C.; Peng, G.; Jing, N.; Wang, Y.; Kellis, M.; Tam, P.; Smith, A.; Piper, M.; Christiaen, L.; Nguyen, Q.; Boden, M.; Palpant, N.
10.1101/635516 — cell biology — Posted on 2020-10-09
3073 Pax7 pioneer factor action requires both paired and homeo DNA binding domains
Pelletier, A.; Mayran, A.; Gouhier, A.; Balsalobre, A.; Omichinski, J. G.; Drouin, J.
10.1101/2020.10.09.332015 — molecular biology — Posted on 2020-10-09
3074 RBMX enables productive RNA processing of ultra-long exons important for genome stability
Luzzi, S.; Hysenaj, G.; Siachisumo, C.; Cheung, K.; Gazzara, M. R.; James, K.; Dalgliesh, C.; Kheirollahi Chadegani, M.; Ehrmann, I.; Smith, G. R.; Cockell, S. J.; Munkley, J.; Barash, Y.; Elliott, D. J.
10.1101/2020.10.09.333039 — molecular biology — Posted on 2020-10-09
3077 Precision Cas9 Genome Editing in vivo with All-in-one, Self-targeting AAV Vectors
Ibraheim, R.; Tai, P. W. L.; Mir, A.; Javeed, N.; Wang, J.; Rodriguez, T. C.; Nelson, S.; Khokhar, E.; Mintzer, E.; Maitland, S.; Cao, Y.; Tsagkaraki, E.; Wolfe, S. A.; Wang, D.; Pai, A. A.; Xue, W.; Gao, G.; Sontheimer, E. J.
10.1101/2020.10.09.333997 — molecular biology — Posted on 2020-10-09
3080 Type I Interferon acts as a major barrier to the establishment of infectious bursal disease virus (IBDV) persistent infections
Broto, L.; Romero, N.; Mendez, F.; Diaz-Beneitez, E.; Candelas-Rivera, O.; Fuentes, D.; Cubas-Gaona, L.; Courtillon, C.; Eterradosi, N.; Soubies, S.; Rodriguez, J. R.; Rodriguez, D.; Rodriguez, J. F.
10.1101/2020.10.09.333161 — microbiology — Posted on 2020-10-09
3082 Calcium signaling through a Transient Receptor Channel is important for Toxoplasma gondii growth
Marquez-Nogueras, K. M.; Chasen, N. M.; Hortua Triana, M. A.; Kuo, I. Y.; Moreno, S.
10.1101/2020.10.09.332593 — microbiology — Posted on 2020-10-09
3083 Unrestrained Gαi2 Signaling Disrupts Normal Neutrophil Trafficking, Aging, and Clearance
Yan, S. L.-S.; Hwang, I.-Y.; Kamenyeva, O.; Kabat, J.; Kim, J. S.; Park, C.; Kehrl, J. H.
10.1101/2020.10.09.333112 — immunology — Posted on 2020-10-09
3084 Intercellular telomere transfer extends T cell lifespan
Vaz, B.; Vuotto, C.; Valvo, S.; D'Ambra, C.; Esposito, F. M.; Chiurchiu, V.; Devine, O.; Sanchez, M.; Borsellino, G.; Gilroy, D.; Akbar, A.; Dustin, M.; Karin, M.; Lanna, A.
10.1101/2020.10.09.331918 — immunology — Posted on 2020-10-09
3088 C/EBPβ-LIP dually activates glycolysis and the malate aspartate shuttle to maintain NADH/NAD+ homeostasis
Ackermann, T.; Zuidhof, H. R.; Kortman, G.; Rutten, M. G. S.; Broekhuis, M. J. C.; Zaini, M. A.; Hartleben, G.; Calkhoven, C. F.
10.1101/2020.10.09.333104 — cancer biology — Posted on 2020-10-09
3090 Stable Protein Sialylation in Physcomitrella
Bohlender, L. L.; Parsons, J.; Hoernstein, S. N. W.; Rempfer, C.; Ruiz-Molina, N.; Lorenz, T.; Rodriguez-Jahnke, F.; Figl, R.; Fode, B.; Altmann, F.; Reski, R.; Decker, E. L.
10.1101/2020.10.09.331033 — bioengineering — Posted on 2020-10-09
3091 Adeno-associated virus capsid assembly is divergent and stochastic
Woerner, T. P.; Bennett, A.; Habka, S.; Snijder, J.; Friese, O. V.; Powers, T. W.; Agbandje-McKenna, M.; Heck, A. J. R.
10.1101/2020.10.09.332619 — biochemistry — Posted on 2020-10-09
3096 HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics
Strom, A. R.; Biggs, R. J.; Banigan, E. J.; Wang, X.; Chiu, K.; Herman, C.; Collado, J.; Yue, F.; Ritland Politz, J. C.; Tait, L. J.; Scalzo, D.; Telling, A.; Groudine, M.; Brangwynne, C. P.; Marko, J.; Stephens, A. D.
10.1101/2020.10.09.331900 — biophysics — Posted on 2020-10-09
3098 Possible transmission flow of SARS-CoV-2 based on ACE2 features
Hassan, S. S.; Ghosh, S.; Attrish, D.; Pal Choudhury, P.; Uversky, V. N.; Uhal, B.; Lundstrom, K.; Rezaei, N.; Aljabali, A. A. A.; Seyran, M.; Pizzol, D.; Adadi, P.; Soares, A.; Abd El-Aziz, T. M.; Kandimalla, R.; Tambuwala, M.; Azad, G. K.; Sherchan, S. P.; Baetas-da-Cruz, W.; Takayama, K.; Serrano-Aroca, A.; Chauhan, G.; Palu, G.; Brufsky, A.
10.1101/2020.10.08.332452 — bioinformatics — Posted on 2020-10-09
3103 Unravelling the evolutionary relationships of hepaciviruses within and across rodent hosts
Bletsa, M.; Vrancken, B.; Gryseels, S.; Boonen, I.; Fikatas, A.; Li, Y.; Laudisoit, A.; Lequime, S.; Bryja, J.; Makundi, R.; Meheretu, Y.; Akaibe, B. D.; Mbalitini, S. G.; Van de Perre, F.; Van Houtte, N.; Tesikova, J.; Wollants, E.; Van Ranst, M.; Drexler, J. F.; Verheyen, E.; Leirs, H.; Gouy de Bellocq, J.; Lemey, P.
10.1101/2020.10.09.332932 — evolutionary biology — Posted on 2020-10-09
3106 Neuroinflammation alters the phenotype of lymphangiogenic vessels near the cribriform plate.
HSU, M.; Madrid, A.; Choi, Y. H.; Laaker, C.; Herbath, M.; Sandor, M.; Fabry, Z.
10.1101/2020.10.08.331801 — immunology — Posted on 2020-10-09
3110 Neural Network Organization for Courtship Song Feature Detection in Drosophila
Baker, C. A.; McKellar, C.; Nern, A.; Dorkenwald, S.; Dickson, B. J.; Murthy, M.
10.1101/2020.10.08.332148 — neuroscience — Posted on 2020-10-09
3114 Isolating the role of corticosterone in the hypothalamic-pituitary-gonadal genomic stress response
Austin, S. H.; Harris, R.; Booth, A. M.; Lang, A.; Farrar, V. S.; Krause, J. S.; Hallman, T. A.; MacManes, M.; Calisi, R. M.
10.1101/2020.10.08.330209 — physiology — Posted on 2020-10-09
3115 Antifragile therapy
West, J.; Strobl, M.; Armagost, C.; Miles, R.; Marusyk, A.; Anderson, A. R. A.
10.1101/2020.10.08.331678 — cancer biology — Posted on 2020-10-09
3117 Fast-Bonito: A Faster Basecaller for Nanopore Sequencing
Xu, Z.; Mai, Y.; Liu, D.; He, W.; Lin, X.; Xu, C.; Zhang, L.; Meng, X.; Mafofo, J.; Zaher, W. A.; Li, Y.; Qiao, N.
10.1101/2020.10.08.318535 — bioinformatics — Posted on 2020-10-09
3118 Omics versus Questionnaires: Using methylation data to assess the environmental impact of smoking on obesity-related traits
Amador, C.; Zeng, Y.; Walker, R. M.; Campbell, A.; McIntosh, A. M.; Evans, K. L.; Porteous, D. J.; Hayward, C.; Wilson, J. F.; Navarro, P.; Haley, C. S.
10.1101/2020.10.08.329672 — genomics — Posted on 2020-10-09
3119 Unbiased identification of nanoparticle cell uptake mechanism via a genome-wide CRISPR/Cas9 knockout screen
Van Nostrand, E. L.; Barnhill, S. A.; Shishkin, A. A.; Nelles, D. A.; Byeon, E.; Nguyen, T.; Wong, Y. C. E.; Gianneschi, N. C.; Yeo, G. W.
10.1101/2020.10.08.332510 — genomics — Posted on 2020-10-09
3120 Humans surviving cholera develop antibodies against Vibrio cholerae O-specific polysaccharide that inhibit pathogen motility
Charles, R. C.; Kelly, M.; Tam, J. M.; Akter, A.; Hossain, M.; Islam, K.; Biswas, R.; Kamruzzaman, M.; Chowdhurry, F.; Khan, A. I.; Leung, D. T.; Weil, A. A.; LaRocque, R. C.; Bhuiyan, T. R.; Rahman, A.; Mayo-Smith, L.; Becker, R. L.; Vyas, J. M.; Faherty, C. S.; Nickerson, K. P.; Giffen, S.; Ritter, A. S.; Waldor, M. K.; Xu, P.; Kovac, P.; Calderwood, S. B.; Kauffman, R. C.; Wrammert, J.; Qadri, F.; Harris, J. B.; Ryan, E. T.
10.1101/2020.10.08.332551 — microbiology — Posted on 2020-10-09
3121 Time-dependent dual effect of NLRP3 inflammasome in brain ischemia
Palomino-Antolin, A.; Narros-Fernandez, P.; Farre-Alins, V.; Sevilla-Montero, J.; Decouty-Perez, C.; Lopez-Rodriguez, A. B.; Fernandez, N.; Monge, L.; Casas, A. I.; Calzada, M. J.; Egea, J.
10.1101/2020.10.08.332007 — neuroscience — Posted on 2020-10-09
3124 In Vivo Validation of Bimolecular Fluorescence Complementation (BiFC) to Investigate Aggregate Formation in Amyotrophic Lateral Sclerosis (ALS)
Don, E. K.; Maschirow, A.; Radford, R. A. W.; Scherer, N. M.; Vidal-Itriago, A.; Hogan, A.; Maurel, C.; Formella, I.; Stoddart, J. J.; Hall, T. E.; Lee, A.; Shi, B.; Cole, N. J.; Laird, A. S.; Badrock, A. P.; Chung, R. S.; Morsch, M.
10.1101/2020.10.08.330894 — neuroscience — Posted on 2020-10-09
3126 Graph-theoretical Analysis of EEG Functional Connectivity during Balance Perturbation in Traumatic Brain Injury.
Shenoy Handiru, V.; Alivar, A.; Selvan, S. E.; Hoxha, A.; Saleh, S.; Yue, G. H.; Allexandre, D.
10.1101/2020.10.08.332353 — neuroscience — Posted on 2020-10-09
3129 Oxygen-generating cryogels restore T cell-mediated cytotoxicity in hypoxic tumors
Colombani, T.; Eggermont, L. J.; Hatfield, S. M.; Rezaeeyazdi, M.; Memic, A.; Sitkovsky, M. V.; Bencherif, S. A.
10.1101/2020.10.08.329805 — bioengineering — Posted on 2020-10-09
3133 The assembled and annotated genome of the pigeon louse Columbicola columbae, a model ectoparasite
Baldwin-Brown, J. G.; Villa, S. M.; Vickrey, A. I.; Johnson, K. P.; Bush, S. E.; Clayton, D. H.; Shapiro, M. D.
10.1101/2020.10.08.330514 — genomics — Posted on 2020-10-09
3136 Rainbow smelt population responses to species invasions and change in environmental condition
Bruel, R.; Marsden, J. E.; Pientka, B.; Staats, N.; Mihuc, T.; Stockwell, J. D.
10.1101/2020.10.08.332205 — ecology — Posted on 2020-10-09
3140 Circadian fluctuations in glucocorticoid level impact perceptual sensitivity
Obleser, J.; Kreitewolf, J.; Vielhauer, R.; Lindner, F.; David, C.; Oster, H.; Tune, S.
10.1101/2020.10.07.330282 — neuroscience — Posted on 2020-10-09
3143 Constitutive deletion of translin (Tsn) enhances locomotor response to amphetamine: role of developmental effects
Fu, X.; Shah, A. P.; Keighron, J.; Mou, T.-C. M.; Ladenheim, B.; Alt, J.; Fukudome, D.; Niwa, M.; Sawa, A.; Cadet, J.-L.; Rais, R.; Tanda, G.; Baraban, J. M.
10.1101/2020.10.08.331447 — neuroscience — Posted on 2020-10-09
3145 Single-cell transcriptomes of developing and adult olfactory receptor neurons in Drosophila
McLaughlin, C. N.; Brbic, M.; Xie, Q.; Li, T.; Horns, F.; Kolluru, S. S.; Kebschull, J. M.; Vacek, D.; Xie, A.; Li, J.; Jones, R. C.; Leskovec, J.; Quake, S. R.; Luo, L.; Li, H.
10.1101/2020.10.08.332130 — neuroscience — Posted on 2020-10-09
3146 The Polyadenosine RNA Binding Protein ZC3H14 is Required in Mice for Proper Dendritic Spine Density
Jones, S. K.; Rha, J.; Kim, S.; Morris, K. J.; Omotade, O. F.; Moberg, K. H.; Myers, K. R.; Corbett, A. H.
10.1101/2020.10.08.331827 — neuroscience — Posted on 2020-10-09
3147 Aging alters the mediating effect of endogenous GABA on the interaction between functional connectivity and motor-state transitions.
Heise, K.-F.; Rueda Delgado, L. M.; Chalavi, S.; King, B. R.; Santos Monteiro, T.; Edden, R. A. E.; Mantini, D.; Swinnen, S. P.
10.1101/2020.10.08.331637 — neuroscience — Posted on 2020-10-09
3150 Identity and provenance of neighbors, genotype-specific traits and abiotic stress affect intraspecific interactions in the annual legume Medicago truncatula
Tomiolo, S.; Damgaard, C.; Zhang, S.; Kelly, S.; Tao, K.; Ronfort, J.; Gay, L.; Prosperi, J.-M.; Radutoiu, S.; Ehlers, B. K.
10.1101/2020.10.08.330944 — plant biology — Posted on 2020-10-09
3152 Neural network dynamics underlying gamma synchronization deficits in schizophrenia
Koshiyama, D.; Miyakoshi, M.; Joshi, Y.; Molina, J.; Tanaka-Koshiyama, K.; Sprock, J.; Braff, D.; Swerdlow, N.; Light, G.
10.1101/2020.10.07.330498 — physiology — Posted on 2020-10-09
3154 Neutralizing antibodies from early cases of SARS-CoV-2 infection offer cross-protection against the SARS-CoV-2 D614G variant.
Lee, C. Y.-P.; Amrun, S. N.; Chee, R. S.-L.; Goh, Y. S.; Mak, T. M.; Octavia, S.; Yeo, N.; Chang, Z. W.; Tay, M. Z.; Torres, A.; Carissimo, G.; Poh, C. M.; Fong, S.-W.; Wang, B.; Lee, S.; Young, B.; Tan, S. Y.; Leo, Y. S.; Lye, D. C. B.; Lin, R. T.; Maurer-Stroh, S.; Lee, B. T. K.; Wang, C.-I.; Renia, L.; Ng, L. F. P.
10.1101/2020.10.08.332544 — immunology — Posted on 2020-10-09
3158 Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2
Gasser, R.; Cloutier, M.; Prevost, J.; Fink, C.; Ducas, E.; Ding, S.; Dussault, N.; Landry, P.; Tremblay, T.; Laforce-Lavoie, A.; Lewin, A.; Beaudoin-Bussieres, G.; Laumaea, A.; Medjahed, H.; Larochelle, C.; Richard, J.; Dekaban, G. A.; Dikeakos, J. D.; Bazin, R.; Finzi, A.
10.1101/2020.10.09.333278 — microbiology — Posted on 2020-10-09
3159 METTL3 inhibitors for epitranscriptomic modulation of cellular processes
Moroz-Omori, E. V.; Huang, D.; Bedi, R. K.; Cheriyamkunnel, S. J.; Bochenkova, E.; Dolbois, A.; Rzeczkowski, M. D.; Wiedmer, L.; Sledz, P.; Caflisch, A.
10.1101/2020.09.25.311803 — biochemistry — Posted on 2020-10-09
3160 LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection
Jones, B. E.; Brown-Augsburger, P. L.; Corbett, K. S.; Westendorf, K.; Davies, J.; Cujec, T. P.; Wiethoff, C. M.; Blackbourne, J. L.; Heinz, B. A.; Foster, D.; Higgs, R. E.; Balasubramaniam, D.; Wang, L.; Bidshahri, R.; Kraft, L.; Hwang, Y.; Zentelis, S.; Jepson, K. R.; Goya, R.; Smith, M. A.; Collins, D. W.; Hinshaw, S. J.; Tycho, S. A.; Pellacani, D.; Xiang, P.; Muthuraman, K.; Sobhanifar, S.; Piper, M. H.; Triana, F. J.; Hendle, J.; Pustilnik, A.; Adams, A. C.; Berens, S. J.; Baric, R. S.; Martinez, D. R.; Cross, R. W.; Geisbert, T. W.; Borisevich, V.; Abiona, O.; Belli, H. M.; de Vries, M.
10.1101/2020.09.30.318972 — immunology — Posted on 2020-10-09
3163 ACE2 interaction networks in COVID-19: a physiological framework for prediction of outcome in patients with cardiovascular risk factors
Wicik, Z.; Eyileten, C.; Jakubik, D.; Simoes, S. N.; Martins, D. C.; Pavao, R.; Siller-Matula, J. M.; Postula, M.
10.1101/2020.05.13.094714 — genomics — Posted on 2020-10-09
3165 Non-permissive SARS-CoV-2 infection of neural cells in the developing human brain and neurospheres
Pedrosa, C. d. S. G.; Goto-Silva, L.; Temerozo, J. R.; Gomes, I. C.; Souza, L. R. Q.; Vitoria, G.; Ornelas, I. M.; Karmirian, K.; Mendes, M. A.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Soares, V. C.; Dias, S. d. S. G.; Salerno, J. A.; Puig-Pijuan, T.; Verissimo, C.; Furtado, D. R.; Borges, H. L.; Bozza, P. T.; Rehen, S.; Souza, T. M. L.; Guimaraes, M. Z. P.
10.1101/2020.09.11.293951 — neuroscience — Posted on 2020-10-09
3166 Wide and Deep Learning for Automatic Cell Type Identification
Wilson, C. M.; Fridley, B.; Conejo-Garcia, J.; Wang, X.; Yu, X.
10.1101/2020.10.09.328732 — genomics — Posted on 2020-10-09
3168 Neural dynamics of semantic categorization in semantic variant of Primary Progressive Aphasia.
Borghesani, V.; Dale, C. L.; Lukic, S.; Hinkley, L. B. N.; Lauricella, M.; Shwe, W.; Miziuri, D.; Honma, S.; Miller, Z.; Miller, B. L.; Houde, J.; Gorno-Tempini, M. L.; Nagarajan, S.
10.1101/2020.10.07.329698 — neuroscience — Posted on 2020-10-09
3173 Transcriptional landscape of PTEN loss in primary prostate cancer
Imada, E. L.; Sanchez, D. F.; Dinalankara, W.; Vidotto, T.; Ebot, E. M.; Tyekucheva, S.; Franco, G. R.; Mucci, L.; Loda, M.; Schaeffer, E. M.; Lotan, T.; Marchionni, L.
10.1101/2020.10.08.332049 — cancer biology — Posted on 2020-10-09
3174 Cancer methylomes characterization enabled by Rocker-meth
Benelli, M.; Franceschini, G. M.; Magi, A.; Romagnoli, D.; Biagioni, C.; Migliaccio, I.; Malorni, L.; Di Leo, A.; Demichelis, F.
10.1101/2020.10.09.332759 — cancer biology — Posted on 2020-10-09
3175 Silencing of oncogenic KRAS by mutant-selective small interfering RNA
Papke, B.; Azam, S. H.; Feng, A. Y.; Van Swearingen, A. E. D.; Gutierrez-Ford, C.; Pallan, P. S.; Egli, M.; Cox, A. D.; Der, C. J.; Pecot, C. V.
10.1101/2020.10.08.331835 — cancer biology — Posted on 2020-10-09
3177 Joint automatic metabolite identification and quantification of a set of 1H NMR spectra
Lefort, G.; Liaubet, L.; Marty-Gasset, N.; Canlet, C.; Vialaneix, N.; Servien, R.
10.1101/2020.10.08.331090 — bioinformatics — Posted on 2020-10-09
3178 A Machine Learning approach for assessing drug development risk
Vergetis, V.; Liaropoulos, G.; Georganaki, M.; Dimakakos, A.; Skaltsas, D.; Gorgoulis, V. G.; Tsirigos, A.
10.1101/2020.10.08.331926 — bioinformatics — Posted on 2020-10-09
3183 E-cadherin: Unexpected actor of invadopodia formation in pancreatic cancer
Dobric, A.; Germain, S.; Bonier, R.; Silvy, F.; Audebert, S.; Camoin, L.; Dusetti, N. J.; Soubeyran, P.; Iovanna, J.; Rigot, V.; Andre, F.
10.1101/2020.10.09.332783 — cancer biology — Posted on 2020-10-09
3184 Ultrasound-mediated mechanical forces selectively kill tumor cells
Tijore, A.; Margadant, F.; Yao, M.; Hariharan, A.; Chew, C. A. Z.; Powell, S.; Bonney, G. K.; Sheetz, M.
10.1101/2020.10.09.332726 — cancer biology — Posted on 2020-10-09
3186 Long-term warming effects on the microbiome and nitrogen fixation associated with the moss Racomitrium lanuginosum in Icelandic tundra
Klarenberg, I. J.; Keuschnig, C.; Russi Colmenares, A. J.; Warshan, D.; Jungblut, A. D.; Jonsdottir, I. S.; Vilhelmsson, O.
10.1101/838581 — microbiology — Posted on 2020-10-09
3190 NIAGADS Alzheimer's GenomicsDB: A resource for exploring Alzheimer's Disease genetic and genomic knowledge
Greenfest-Allen, E.; Klamann, C.; Valladares, O.; Kuzma, A.; Gangadharan, P.; Leung, Y. Y.; Stoeckert, C. J.; Wang, L.-S.
10.1101/2020.09.23.310276 — bioinformatics — Posted on 2020-10-09
3191 Mutations in SKI in Shprintzen-Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization
Gori, I.; George, R.; Purkiss, A.; Strohbuecker, S.; Randall, R. A.; Ogrodowicz, R.; Carmignac, V.; Faivre, L.; Joshi, D.; Kjaer, S.; Hill, C. S.
10.1101/2020.10.07.330407 — biochemistry — Posted on 2020-10-09
3193 Transcriptomic Analyses Throughout Chili Pepper Fruit Development Reveal Novel Insights into Domestication Process
Martinez, O.; Arce-Rodriguez, M. L.; Hernandez-Godinez, F.; Escoto-Sandoval, C.; Cervantes-Hernandez, F.; Hayano-Kanashiro, C.; Ordaz-Ortiz, J. J.; Reyes-Valdes, M. H.; Razo-Mendivil, F. G.; Garces-Claver, A.; Ochoa-Alejo, N.
10.1101/2020.10.05.326470 — evolutionary biology — Posted on 2020-10-09
3195 Cellular birthdate predicts laminar and regional cholinergic projection topography in the forebrain
Allaway, K. C.; Munoz, W.; Tremblay, R.; Sherer, M.; Herron, J.; Rudy, B.; Machold, R.; Fishell, G.
10.1101/2020.10.08.331223 — developmental biology — Posted on 2020-10-09
3196 The Hippo pathway controls myofibril assembly and muscle fiber growth by regulating sarcomeric gene expression
Schnorrer, F.; Kaya-Copur, A.; Marchiano, F.; Hein, M. Y.; Alpern, D.; Russeil, J.; Luis, N. M.; Mann, M.; Deplancke, B.; Habermann, B. H.
10.1101/2020.10.08.330951 — developmental biology — Posted on 2020-10-09
3197 RIOK2 phosphorylation by RSK promotes synthesis of the human small ribosomal subunit
Cerezo, E. L.; Houles, T.; Lie, O.; Sarthou, M.-K.; Audoynaud, C.; Lavoie, G.; Halladjian, M.; Cantaloube, S.; Froment, C.; Burlet-Schiltz, O.; Henry, Y.; Roux, P. P.; Henras, A.; Romeo, Y.
10.1101/2020.10.07.329334 — molecular biology — Posted on 2020-10-09
3199 Sequence evaluation and comparative analysis of novel assays for intact proviral HIV-1 DNA
Gaebler, C.; Falcinelli, S. D.; Stoffel, E.; Read, J.; Murtagh, R.; Oliveira, T.; Ramos, V.; Lorenzi, J. C.; Kirchherr, J. L.; James, K. S.; Allard, B.; Baker, C.; Kuruc, J. D.; Caskey, M.; Archin, N.; Siliciano, R. F.; Margolis, D. M.; Nussenzweig, M. C.
10.1101/2020.10.07.330787 — microbiology — Posted on 2020-10-09
3200 SARS-CoV-2 Elicits Robust Adaptive Immune Responses Regardless of Disease Severity
Nielsen, S. S. F.; Vibholm, L. K.; Monrad, I.; Olesen, R.; Frattari, G. S.; Pahus, M. H.; Hojen, J. F.; Gunst, J. D.; Erikstrup, C.; Holleufer, A.; Hartmann, R.; Ostergaard, L.; Sogaard, O. S.; Schleimann, M. H.; Tolstrup, M.
10.1101/2020.10.08.331645 — immunology — Posted on 2020-10-09
3201 Uncovering biomarkers during therapeutic neuromodulation with PARRM: Period-based Artifact Reconstruction and Removal Method
Dastin-van Rijn, E. M.; Provenza, N. R.; Calvert, J. S.; Gilron, R.; Allawalla, A. B.; Darie, R.; Syed, S.; Matteson, E.; Vogt, G. S.; Avendano-Ortega, M.; Vasquez, A. C.; Ramakrishnan, N.; Oswalt, D. N.; Bijanki, K. R.; Wilt, R.; Starr, P. A.; Sheth, S. A.; Goodman, W. K.; Harrison, M. T.; Borton, D. A.
10.1101/2020.10.02.322743 — neuroscience — Posted on 2020-10-09
3202 Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun
Wagstaff, L. J.; Gomez-Sanchez, J. A.; Fazal, S. V.; Otto, G.; Kilpatrick, A. M.; Michael, K.; Wong, L. Y. N.; Ma, K. H.; Turmaine, M.; Svaren, J.; Gordon, T.; Arthur-Farraj, P.; Velasco-Aviles, S.; Cabedo, H.; Benito, C.; Mirsky, R.; Jessen, K. R.
10.1101/2020.10.06.327957 — neuroscience — Posted on 2020-10-09
3204 exosome-LncPICALM-AU1 regulates endothelial-mesenchymal transition in hepatopulmonary syndrome
Yang, C.; Yang, Y.; Chen, Y.; Huang, J.; Li, Y.; Zhi, H.; Tang, X.; Wang, X.; Belguise, K.; Xia, Z.; Ning, J.; Gu, J.; Yi, B.; lu, K.
10.1101/2020.10.06.327874 — pathology — Posted on 2020-10-09
3207 Space-time logic of liver gene expression at sublobular scale
Droin, C.; El Kholtei, J.; Bahar Halpern, K.; Hurni, C.; Rozenberg, M.; Muvkadi, S.; Itzkovitz, S.; Naef, F.
10.1101/2020.03.05.976571 — systems biology — Posted on 2020-10-09
3208 Efficient cooperation of chloroplasts and mitochondria enhances ATP and sucrose production
Voon, C. P.; Law, Y.-S.; Guan, X.; Xu, Z.; Chu, W.-T.; Zhang, R.; Sun, F.; Labs, M.; Pribil, M.; Leister, D.; Hronkova, M.; Kubasek, J.; Cui, Y.; Jiang, L.; Tsuyama, M.; Gardestrom, P.; Tikkanen, M.; Lim, B. L.
10.1101/2020.09.09.289967 — plant biology — Posted on 2020-10-09
3209 Effects of genetic variability of CYP2D6 on neural substrates of sustained attention during on-task activity
Viviani, R.; Messina, I.; Bosch, J. E.; Dommes, L.; Paul, A.; Schneider, K. L.; Scholl, C.; Stingl, J. C.
10.1101/831198 — pharmacology and toxicology — Posted on 2020-10-09
3210 Deubiquitinase UCHL1 Maintains Protein Homeostasis through PSMA7-APEH-Proteasome Axis in High-Grade Serous Ovarian Carcinoma
Tangri, A.; Lighty, K.; Loganathan, J.; Mesmar, F.; Podicheti, R.; Zhang, C.; Iwanicki, M.; Nakshatri, H.; Mitra, S.
10.1101/2020.09.28.316810 — cancer biology — Posted on 2020-10-09
3215 Structure and mechanism of TRAPPIII-mediated Rab1 activation
Joiner, A. M. N.; Phillips, B. P.; Yugandhar, K.; Sanford, E. J.; Smolka, M. B.; Yu, H.; Miller, E. A.; Fromme, J. C.
10.1101/2020.10.08.332312 — cell biology — Posted on 2020-10-08
3217 Electrophysiological investigation of reward anticipation and outcome evaluation during slot machine play
Fryer, S. L.; Roach, B. J.; Holroyd, C.; Paulus, M.; Sargent, K.; Boos, A.; Ford, J.; Mathalon, D. H.
10.1101/2020.10.08.330654 — neuroscience — Posted on 2020-10-08
3219 Multi-modal imaging of a single postmortem mouse brain over five orders of magnitude of resolution
Foxley, S.; Sampathkumar, V.; De Andrade, V.; Trinkle, S.; Sorokina, A.; Li, H.; Norwood, K.; La Riviere, P.; Kasthuri, N.
10.1101/2020.10.07.329789 — neuroscience — Posted on 2020-10-08
3220 FARCI: Fast and Robust Connectome Inference
Meamardoost, S.; Bhattacharya, M.; Hwang, E.; Komiyama, T.; Mewes, C. K.; Wang, L.; Zhang, Y.; Gunawan, R.
10.1101/2020.10.07.330175 — neuroscience — Posted on 2020-10-08
3221 Action potential-coupled Rho GTPase signaling drives presynaptic plasticity
Dube, S.; Racz, B.; Brown, W. E.; Gao, Y.; Soderblom, E. J.; Yasuda, R.; Soderling, S. H.
10.1101/2020.10.07.330126 — neuroscience — Posted on 2020-10-08
3223 NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4
Jain, P.; Dvorkin-Gheva, A.; Mollen, E.; Xie, M.; Jessa, F.; Dhavarasa, P.; Chung, S.; Brown, K. R.; Jang, G. H.; Notta, F.; Moffat, J.; Hedley, D.; Boutros, P. C.; Wouters, B. G.; Koritzinsky, M.
10.1101/2020.10.08.330035 — cancer biology — Posted on 2020-10-08
3225 Accurate assembly of minority viral haplotypes from next-generation sequencing through efficient noise reduction
Knyazev, S.; Tsyvina, V.; Melnyk, A.; Artyomenko, A.; Malygina, T.; Porozov, Y. B.; Campbell, E.; Mangul, S.; Switzer, W. M.; Skums, P.; Zelikovsky, A.
10.1101/264242 — bioinformatics — Posted on 2020-10-08
3227 Whole-genome SNP analysis elucidates the genetic population structure and diversity of Acrocomia species
Diaz, B. G.; Zucchi, M. I.; Alves-Pereira, A.; de Almeida, C. P.; Moraes, A.; Vianna, S. A.; Azevedo-Filho, J.; COLOMBO, C. A.
10.1101/2020.10.08.331140 — genetics — Posted on 2020-10-08
3228 Discovery of novel tumor suppressors from CRISPR screens reveals lipid-sensitive subtype of AML
Lenoir, W. F.; Morgado, M.; DeWeirdt, P. C.; McLaughlin, M.; Griffith, A. L.; Sangree, A. K.; Feeley, M. N.; Kim, E.; Colic, M.; Dede, M.; Doench, J. G.; Hart, T.
10.1101/2020.10.08.332023 — genetics — Posted on 2020-10-08
3230 Hsp90 and its co-chaperone Sti1 control TDP-43 misfolding and toxicity
Duennwald, M.; Lin, L. T.-W.; Razzaq, A. R.; Di Gregorio, S. E.; Hong, S.; Charles, B.; Lopes, M. H.; Beraldo, F.; Prado, V.; Prado, M.
10.1101/2020.10.08.331173 — cell biology — Posted on 2020-10-08
3232 Biting and resting preferences of malaria vectors in The Gambia
Hamid-Adiamoh, M.; Nwakanma, D.; Assogba, B. S.; Ndiath, M. O.; DAlessandro, U.; Afrane, Y. A.; Amambua-Ngwa, A.
10.1101/2020.10.08.331165 — molecular biology — Posted on 2020-10-08
3233 Isolation and characterization of lumpy skin disease virus from cattle in India
Kumar, N.; Chander, Y.; Kumar, R.; Khandelwal, N.; Riyesh, T.; Chaudhary, K.; Shanmugasundaram, K.; Kumar, S.; Kumar, A.; Gupta, M. K.; Pal, Y.; Barua, S.; Tripathi, B. N.
10.1101/2020.10.08.331124 — microbiology — Posted on 2020-10-08
3234 Bathyarchaeota Occurence in Shallow Marine Methane-rich Sediments (Saco Do Mamangua, Rio de Janeiro, Brazil)
Romano, R. G.; Bendia, A. G.; Franco, D. C.; Signori, C. N.; Yu, T.; Wang, F.; Jovane, L.; Pellizari, V. H.
10.1101/2020.10.07.329656 — microbiology — Posted on 2020-10-08
3236 The Rpi-mcq1 resistance gene family recognizes Avr2 of Phytophthora infestans but is distinct from R2
Aguilera-Galvez, C.; Chu, Z.; Sumaiya Haque, O.; Wouters, D.; Gilroy, E.; Vossen, J.; Visser, R.; Birch, P.; Jones, J.; Vleeshouwers, V. G. A. A.
10.1101/2020.10.08.331181 — plant biology — Posted on 2020-10-08
3237 CD73 maintains hepatocyte metabolic integrity and mouse liver homeostasis in a sex-dependentmanner
Alcedo, K. P.; Rouse, M. A.; Jung, G. S.; Fu, D.; Minor, M.; Willcockson, H. H.; Greene, K.; Snider, N. T.
10.1101/2020.10.08.328930 — physiology — Posted on 2020-10-08
3238 High contrast probe cleavage detection on porous silicon biosensors via quantum dot labeled DNA probes
Dubrovsky, M.; Layouni, R.; Bao, M.; Chung, H.; Du, K.; Boriskina, S. V.; Weiss, S. M.; Vermeulen, D.
10.1101/2020.10.07.330589 — bioengineering — Posted on 2020-10-08
3239 A contiguous de novo genome assembly of sugar beet EL10 (Beta vulgaris L.)
McGrath, J. M.; Funk, A.; Galewski, P.; Ou, S.; Townsend, B. J.; Davenport, K.; Daligault, H.; Johnson, S.; Lee, J.; Hastie, A. R.; Darracq, A.; Willems, G.; Barnes, S.; Liachko, I.; Sullivan, S.; Koren, S.; Phillippy, A.; Wang, J.; Liu, T.; Pulman, J. A.; Childs, K.; Yocum, A.; Fermin, D.; Mutasa-Gottgens, E.; Stevanato, P.; Taguchi, K.; Dorn, K.
10.1101/2020.09.15.298315 — genomics — Posted on 2020-10-08
3242 Synergistic effect of deoxynucleosides and AAV gene therapy for thymidine kinase 2 deficiency
Lopez-Gomez, C.; Sanchez-Quintero, M. J.; Lee, E. J.; Kleiner, G.; Xie, J.; Akman, H. O.; Gao, G.; Hirano, M.
10.1101/2020.10.08.330969 — genetics — Posted on 2020-10-08
3247 Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks
Schneider, W. M.; Luna, J. M.; Hoffmann, H.- H.; Sanchez-Rivera, F. J.; Leal, A. A.; Ashbrook, A. W.; Le Pen, J.; Michailidis, E.; Ricardo-Lax, I.; Peace, A.; Stenzel, A. F.; Lowe, S. W.; MacDonald, M. R.; Rice, C. M.; Poirier, J. T.
10.1101/2020.10.07.326462 — microbiology — Posted on 2020-10-08
3249 Persistence of Zika virus RNA in the epididymis of the male reproductive tract
Vogt, M. B.; Frere, F.; Hawks, S. A.; Perez, C. E.; Coutermarsh-Ott, S.; Duggal, N. K.
10.1101/2020.10.08.330019 — microbiology — Posted on 2020-10-08
3250 Microglia Stimulate Zebrafish Brain Repair Via a Specific Inflammatory Cascade
Kanagaraj, P.; Chen, J. Y.; Skaggs, K.; Qadeer, Y.; Conner, M.; Cutler, N.; Richmond, J.; Kommidi, V.; Poles, A.; Affrunti, D.; Powell, C.; Goldman, D.; Parent, J. M.
10.1101/2020.10.08.330662 — neuroscience — Posted on 2020-10-08
3253 Genetic Analysis of Methyl Anthranilate, Mesifurane, Linalool and Other Flavor Compounds in Cultivated Strawberry (Fragaria xananassa)
Barbey, C. R.; Hogshead, M. H.; Harrison, B.; Schwartz, A. E.; Verma, S.; Oh, Y.; Lee, S.; Folta, K. M.; Whitaker, V. M.
10.1101/2020.10.07.330001 — plant biology — Posted on 2020-10-08
3258 Preferential recognition and antagonism of SARS-CoV-2 spike glycoprotein binding to 3-O-sulfated heparan sulfate
Tiwari, V.; Tandon, R.; Sankaranarayanan, N. V.; Beer, J. C.; Kohlmeir, E. K.; Swanson-Mungerson, M.; Desai, U. R.
10.1101/2020.10.08.331751 — biochemistry — Posted on 2020-10-08
3260 Drug-induced resistance evolution necessitates less aggressive treatment
Kuosmanen, T.; Cairns, J.; Noble, R.; Beerenwinkel, N.; Mononen, T.; Mustonen, V.
10.1101/2020.10.07.330134 — evolutionary biology — Posted on 2020-10-08
3261 Intraspecific diversity loss in a predator species alters prey community structure and ecosystem functions
Raffard, A.; Cucherousset, J.; Montoya, J. M.; Richard, M.; Acoca-Pidolle, S.; Poesy, C.; Garreau, A.; Santoul, F.; Blanchet, S.
10.1101/2020.06.10.144337 — ecology — Posted on 2020-10-08
3262 Tau forms oligomeric complexes on microtubules that are distinct from pathological oligomers in disease
Gyparaki, M. T.; Arab, A.; Sorokina, E. M.; Santiago-Ruiz, A. N.; Bohrer, C. H.; Xiao, J.; Lakadamyali, M.
10.1101/2020.07.07.192146 — cell biology — Posted on 2020-10-08
3264 Function expansion of antitumor transcriptional activator NFE2L1 by the original discovery of its non-transcription factor activity
Lu, Q.; Qiufang, Y.; Peng, L.; Xiaowen, Z.; Yonghui, Y.; Xiuman, Z.; Shanshan, G.; Wenjie, Z.; Guodong, L.; Yonggang, R.; Wenshan, Z.; Yahong, W.; Yuanming, Q.; Yanfeng, G.
10.1101/2020.10.08.330597 — molecular biology — Posted on 2020-10-08
3269 Distinct human gut microbial taxonomic signatures uncovered with different sample processing and microbial cell disruption methods for metaproteomic analysis
Garcia-Duran, C.; Martinez-Lopez, R.; Zapico, I.; Perez, E.; Romeu, E.; Arroyo, J.; Hernaez, M. L.; Pitarch, A.; Monteoliva Diaz, L.; Gil, C.
10.1101/2020.10.08.331066 — microbiology — Posted on 2020-10-08
3270 Atypical molecular basis for drug resistance to mitochondrial function inhibitors in Plasmodium falciparum
Painter, H. J.; Morrisey, J. M.; Mather, M. W.; Orchard, L. M.; Luck, C.; Smilkstein, M. J.; Riscoe, M. K.; Vaidya, A. B.; Llinas, M.
10.1101/2020.10.08.330241 — microbiology — Posted on 2020-10-08
3271 CD8+ T cell responses in convalescent COVID-19 individuals target epitopes from the entireSARS-CoV-2 proteome and show kinetics of early differentiation
Kared, H.; Redd, A. D.; Bloch, E. M.; Bonny, T. S.; Sumatoh, H.; Kairi, F.; Carbajo, D.; Abel, B.; Newell, E. W.; Bettinotti, M. P.; Benner, S. E.; Patel, E. U.; Littlefield, K.; Laeyendecker, O.; Shoham, S.; Sullivan, D.; Casadevall, A.; Pekosz, A.; Nardin, A.; Fehlings, M.; Tobian, A. A.; Quinn, T. C.
10.1101/2020.10.08.330688 — immunology — Posted on 2020-10-08
3273 Tumor-responsive, multifunctional CAR-NK cells cooperate with impaired autophagy to infiltrate and target glioblastoma
Wang, J.; Torregrosa-Allen, S.; Elzey, B. D.; Utturkar, S.; Lanman, N. A.; Bernal-Crespo, V.; Behymer, M. M.; Knipp, G. T.; Yun, Y.; Veronesi, M. C.; Sinn, A. L.; Pollok, K. E.; Brutkiewicz, R. R.; Nevel, K. S.; Matosevic, S.
10.1101/2020.10.07.330043 — immunology — Posted on 2020-10-08
3274 A novel polymorphism in nitric oxide synthase interacting protein (NOSIP) modulates nitric oxide and mortality in Human Sepsis
Mukherjee, R.; Singh, D. K.; Patra, R.; Barman, P. K.; Prusty, B. K.; Thatoi, P.; Tripathy, R.; Das, B. K.; Ravindran, B.
10.1101/038398 — immunology — Posted on 2020-10-08
3276 Sexually dimorphic influence of the circadian clock gene Bmal1 in the striatum on alcohol intake
de Zavalia, N.; Schottner, K.; Goldsmith, J. A.; Solis, P.; Ferraro, S.; Parent, G.; Amir, S.
10.1101/2020.09.16.299842 — neuroscience — Posted on 2020-10-08
3283 Power-law behaviour of transcription factor dynamics at the single-molecule level implies a continuum affinity model
Garcia, D. A.; Fettweis, G.; Presman, D. M.; Paakinaho, V.; Jarzynski, C.; Upadhyaya, A.; Hager, G. L.
10.1101/637355 — biophysics — Posted on 2020-10-08
3284 A patient-designed tissue-engineered model of the infiltrative glioblastoma microenvironment
Cornelison, R. C.; Yuan, J. X.; Tate, K. M.; Petrosky, A.; Beeghly, G. F.; Bloomfield, M.; Schwager, S. R.; Berr, A. L.; Cimini, D.; Bafakih, F. F.; Mandell, J. W.; Purow, B. W.; Horton, B. J.; Munson, J.
10.1101/2020.10.02.322735 — bioengineering — Posted on 2020-10-08
3285 The genomics of mimicry: gene expression throughout development provides insights into convergent and divergent phenotypes in a Mullerian mimicry system
Stuckert, A. M. M.; Chouteau, M.; McClure, M.; LaPolice, T. M.; Linderoth, T.; Nielsen, R.; Summers, K.; MacManes, M. D.
10.1101/706671 — evolutionary biology — Posted on 2020-10-08
3287 Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network.
Hutchings, J.; Stancheva, V. G.; Brown, N. R.; Cheung, A. M.; Miller, E. A.; Zanetti, G.
10.1101/2020.06.18.159608 — cell biology — Posted on 2020-10-08
3290 Lynx1 regulates nAChRs to preserve the structure and function of neuromuscular synapses during aging
Doss, S. V.; Barbat-Artigas, S.; Myers, T.; Pradhan, B. S.; Proszynski, T. J.; Robitaille, R.; Valdez, G.
10.1101/2020.05.29.123851 — neuroscience — Posted on 2020-10-08
3291 Comparing quality of reporting between preprints and peer-reviewed articles in the biomedical literature
Carneiro, C. F. D.; Queiroz, V. G. S.; Moulin, T. C.; Carvalho, C. A. M.; Haas, C. B.; Rayee, D.; Henshall, D. E.; De-Souza, E. A.; Amorim, F. E.; Boos, F. Z.; Guercio, G. D.; Costa, I. R.; Hajdu, K. L.; van Egmond, L.; Modrak, M.; Tan, P. B.; Abdill, R. J.; Burgess, S. J.; Guerra, S. F. S.; Bortoluzzi, V. T.; Amaral, O. B.
10.1101/581892 — scientific communication and education — Posted on 2020-10-08
3292 Cardiomyocyte Contractile Impairment in Heart Failure Results from Reduced BAG3-mediated Sarcomeric Protein Turnover
Martin, T. G.; Myers, V. D.; Dubey, P.; Perez, E.; Morevac, C. S.; Willis, M. S.; Feldman, A. M.; Kirk, J. A.
10.1101/2020.04.10.022319 — physiology — Posted on 2020-10-08
3293 The transcriptome of regenerating zebrafish scales identifies genes involved in human bone disease
Bergen, D. J. M.; Tong, Q.; Shukla, A.; Newham, E.; Zethof, J.; Lundberg, M.; Ryan, R.; Youlten, S. E.; Zeggini, E.; Croucher, P. I.; Flik, G.; Richardson, R. J.; Kemp, J. P.; Hammond, C. L.; Metz, J. R.
10.1101/2020.10.08.331561 — genetics — Posted on 2020-10-08
3295 Rapid Cortical Adaptation and the Role of Thalamic Synchrony During Wakefulness
Wright, N. C.; Borden, P. Y.; Liew, Y. J.; Bolus, M. F.; Stoy, W. M.; Forest, C. R.; Stanley, G. B.
10.1101/2020.10.08.331660 — neuroscience — Posted on 2020-10-08
3297 Cyanobacterial NOS expression improves nitrogen use efficiency, nitrogen-deficiency tolerance and yield in Arabidopsis
Del Castello, F.; Foresi, N.; Nejamkin, A.; Lindermayr, C.; Buegger, F.; Lamattina, L.; Correa-Aragunde, N.
10.1101/2020.10.08.331702 — plant biology — Posted on 2020-10-08
3300 Discriminative SKP2 interactions with CDK-cyclin complexes support a cyclin A-specific role in p27KIP1 degradation
Salamina, M.; Montefiore, B. C.; Liu, M.; Wood, D. J.; Heath, R.; Ault, J. R.; Wang, L.-Z.; Korolchuk, S.; Basle, A.; Pastok, M. W.; Reeks, J.; Tatum, N. J.; Sobott, F.; Arold, S. T.; Pagano, M.; Noble, M. E. M.; Endicott, J. A.
10.1101/2020.10.08.329599 — biochemistry — Posted on 2020-10-08
3307 Gene Therapy Reforms Photoreceptor Structure and Restores Vision in NPHP5-associated Leber Congenital Amaurosis
Aguirre, G. D.; Cideciyan, A. V.; Dufour, V. L.; Ripolles Garcia, A.; Sudharsan, R.; Swider, M.; Nikonov, R.; Iwabe, S.; Boye, S. L.; Hauswirth, W. W.; Jacobson, S. G.; Beltran, W. A.
10.1101/2020.10.07.329821 — neuroscience — Posted on 2020-10-08
3308 A fluorescent sensor for spatiotemporally resolved endocannabinoid dynamics in vitro and in vivo
Dong, A.; He, K.; Dudok, B.; Farrell, J. S.; Guan, W.; Liput, D. J.; Puhl, H. L.; Cai, R.; Duan, J.; Albarran, E.; Ding, J.; Lovinger, D. M.; Li, B.; Soltesz, I.; Li, Y.
10.1101/2020.10.08.329169 — neuroscience — Posted on 2020-10-08
3310 Schengen-pathway controls spatially separated and chemically distinct lignin deposition in the endodermis.
Reyt, G.; Ramakrishna, P.; Salas-Gonzalez, I.; Fujita, S.; Love, A.; Tiemessen, D.; Lapierre, C.; Morreel, K.; Calvo Polanco, M.; Flis, P.; Geldner, N.; Boursiac, Y.; Boerjan, W.; George, M. W.; Castrillo, G.; Salt, D. E.
10.1101/2020.10.07.329664 — plant biology — Posted on 2020-10-08
3312 ES-62 suppression of arthritis reflects epigenetic rewiring of synovial fibroblasts to a joint-protective phenotype
Corbet, M.; Pineda, M. A.; Yang, K.; Tarafdar, A.; McGrath, S.; Nakagawa, R.; Lumb, F. E.; Harnett, W.; Harnett, M. M.
10.1101/2020.10.08.331942 — pathology — Posted on 2020-10-08
3313 RAL GTPases mediate EGFR/MAPK signalling-driven intestinal stem cell proliferation and tumourigenesis upstream of RAS activation.
Naszai, M.; Yu, Y.; Roman Fernandez, A.; Sandilands, E.; Johansson, J.; Norman, J. C.; Sansom, O. J.; Bryant, D.; Cordero, J. B.
10.1101/2020.10.07.329607 — cancer biology — Posted on 2020-10-08
3316 Transcribed germline-limited coding sequences in Oxytricha trifallax
Landweber, L. F.; Miller, R. V.; Neme, R.; Clay, D.; Pathmanathan, J.; Lu, M. W.; Yerlici, V. T.; Khurana, J. S.
10.1101/2020.10.07.330092 — genomics — Posted on 2020-10-08
3324 α-Endosulfine regulates amyloid β42 via the modulation of neprilysin activity
Watamura, N.; Kakiya, N.; Nilsson, P.; Tsubuki, S.; Kamano, N.; Takahashi, M.; Hashimoto, S.; Sasaguri, H.; Saito, T.; Saido, T.
10.1101/2020.10.07.329318 — neuroscience — Posted on 2020-10-08
3328 Repeatability of soma and neurite metrics incortical and subcortical grey matter
Genc, S.; Chamberland, M.; Koller, K.; Tax, C. M. W.; Zhang, H.; Palombo, M.; Jones, D. K.
10.1101/2020.10.08.331595 — neuroscience — Posted on 2020-10-08
3332 Gene network modeling via TopNet reveals robust epistatic interactions between functionally diverse tumor critical mediator genes
McMurray, H. R.; Ambeskovic, A.; Newman, L. A.; Aldersley, J.; Balakrishnan, V.; Smith, B.; Stern, H. A.; Land, H.; McCall, M. N.
10.1101/2020.10.07.328542 — cancer biology — Posted on 2020-10-08
3343 First report of Infectious Spleen and Kidney Necrosis Virus in Nile tilapia in Brazil.
Figueiredo, H. C. P.; Tavares, G. C.; Dorella, F. A.; Rosa, J. C. C.; Marcelino, S. A. C.; Pierezan, F. P.
10.1101/2020.10.08.331991 — microbiology — Posted on 2020-10-08
3344 Tissue-specific transcription footprinting using RNA PoI DamID (RAPID) in C. elegans
Gomez-Saldivar, G.; Osuna-Luque, J.; Semple, J. I.; Glauser, D. A.; Jarriault, S.; Meister, P.
10.1101/2020.08.19.257873 — genetics — Posted on 2020-10-08
3347 Screening of Cultivars for Tissue Culture Response and Establishment of Genetic Transformation in a High-yielding and Disease-resistant Cultivar of Theobroma cacao
Jones, J.; Zhang, E.; Tucker, D.; Rietz, D.; Dahlbeck, D.; Gomez, M.; Garcia, C.; Marelli, J.-P.; Livingstone, D.; Schnell, R.; Staskawicz, B.; Cho, M.-J.
10.1101/2020.10.07.327486 — plant biology — Posted on 2020-10-08
3351 Human USP18 is regulated by miRNAs via the 3'UTR, a sequence duplicated in lincRNA genes residing in chr22q11.21
Rubino, E.; Cruciani, M.; Tchitchek, N.; Le Tortorec, A.; Rolland, A.; Veli, O.; Vallet, L.; Gaggi, G.; Michel, F.; Dejucq-Rainsford, N.; Pellegrini, S.
10.1101/2020.10.07.328385 — immunology — Posted on 2020-10-08
3355 Single-nucleus transcriptome analysis reveals cell type-specific molecular signatures across reward circuitry in the human brain
Tran, M. N.; Maynard, K. R.; Spangler, A.; Collado Torres, L.; Sadashivaiah, V.; Tippani, M.; Barry, B. K.; Hancock, D. B.; Hicks, S. C.; Kleinman, J. E.; Hyde, T. M.; Martinowich, K.; Jaffe, A. E.
10.1101/2020.10.07.329839 — neuroscience — Posted on 2020-10-08
3357 LED light gradient as a screening tool for light quality responses in model plant species
Lejeune, P.; Fratamico, A.; Bouche, F.; Huerga-Fernandez, S.; Tocquin, P.; Perilleux, C.
10.1101/2020.10.08.320002 — plant biology — Posted on 2020-10-08
3358 Pharmacological inhibition of the ALK axis elicits therapeutic potential in Consensus Molecular Subtype 1 colon cancer patients
Mazzeschi, M.; Sgarzi, M.; Romaniello, D.; Gelfo, V.; Cavallo, C.; Santi, S.; Fiorentino, M.; D'Uva, G.; Gyorffy, B.; Palmer, R.; Lauriola, M.
10.1101/2020.10.07.307991 — cancer biology — Posted on 2020-10-08
3360 Phosphoproteomics identifies PI3K inhibitor-selective adaptive responses in pancreatic cancer cell therapy and resistance
Cintas, C.; Douche, T.; Dantes, Z.; Mouton-Barbosa, E.; Bousquet, M.-P.; Therville, N.; Pont, F.; Cayron, C.; Ramos-Delgado, F.; Thibault, B.; Garmy-Susini, B.; Cappello, P.; Burlet-Schiltz, O.; Hirsch, E.; Gomez-Brouchet, A.; Reichert, M.; Guillermet-Guibert, J.
10.1101/2020.10.08.313833 — cancer biology — Posted on 2020-10-08
3361 Creating Clear and Informative Image-based Figures for Scientific Publications
Jambor, H.; Antonietti, A.; Alicea, B. J.; Audisio, T. L.; Auer, S.; Bhardwaj, V.; Burgess, S. J.; Ferling, I.; Gazda, M. A.; Hoeppner, L. H.; Ilangovan, V.; Lo, H.; Olson, M.; Mohamed, S. Y.; Sarabipour, S.; Varma, A.; Walavalkar, K.; Wissink, E.; Weissgerber, T. L.
10.1101/2020.10.08.327718 — bioinformatics — Posted on 2020-10-08
3362 Deep-LUMEN Assay - Human lung epithelial spheroid classification from brightfield images using deep learning
Abdul, L.; Rajasekar, S.; S.Y. Lin, D.; Venkatasubramania Raja, S.; Sotra, A.; Feng, Y.; Liu, A.; Zhang, B.
10.1101/2020.10.07.328005 — bioengineering — Posted on 2020-10-08
3364 Ancestral dietary change alters development of Drosophila larvae through MAPK signalling
Towarnicki, S. G.; Youngson, N. A.; Corley, S. M.; St John, J. C.; Turner, N.; Morris, M. J.; Ballard, J. W. O.
10.1101/2020.10.07.327478 — developmental biology — Posted on 2020-10-08
3365 De novo structural mutation rates and gamete-of-origin biases revealed through genome sequencing of 2,396 families
Belyeu, J. R.; Brand, H.; Wang, H.; Zhao, X.; Pedersen, B. S.; Feusier, J.; Gupta, M.; Nicholas, T. J.; Baird, L.; Devlin, B.; Sanders, S. J.; Jorde, L. B.; Talkowski, M. E.; Quinlan, A. R.
10.1101/2020.10.06.329011 — genomics — Posted on 2020-10-08
3368 Applying Machine Learning to Increase Efficiency and Accuracy of Meta-Analytic Review
Gorelik, A. J.; Gorelik, M. G.; Ridout, K. K.; Nimarko, A. F.; Peisch, V.; Kuramkote, S. R.; Low, M.; Pan, T.; Singh, S.; Nrusimha, A.; Singh, M. K.
10.1101/2020.10.06.314245 — neuroscience — Posted on 2020-10-08
3369 Stock market fluctuations impact the emotional brain on a population level.
Lebedev, A. V.; Abe, C.; Acar, K.; Thompson, W. H.; Ingvar, M.; Petrovic, P.
10.1101/2020.10.07.329201 — neuroscience — Posted on 2020-10-08
3373 EMPress enables tree-guided, interactive, and exploratory analyses of multi-omic datasets
Cantrell, K.; Fedarko, M. W.; Rahman, G.; McDonald, D.; Yang, Y.; Zaw, T.; Gonzalez, A.; Janssen, S.; Estaki, M.; Haiminen, N.; Beck, K. L.; Zhu, Q.; Sayyari, E.; Morton, J.; Tripathi, A.; Gauglitz, J. M.; Marotz, C.; Matteson, N. L.; martino, c.; Sanders, J. G.; Carrieri, A. P.; Song, S. J.; Swafford, A. D.; Dorrestein, P.; Andersen, K. G.; PARIDA, L.; Kim, H.-C.; Vazquez-Baeza, Y.; Knight, R.
10.1101/2020.10.06.327080 — bioinformatics — Posted on 2020-10-08
3374 A hierarchical point process model for spatial capture-recapture data
Zhang, W.; Chipperfield, J. D.; Illian, J. B.; Dupont, P.; Milleret, C.; de Valpine, P.; Bischof, R.
10.1101/2020.10.06.325035 — ecology — Posted on 2020-10-08
3375 A virulence associated siderophore importer causes antimicrobial efflux in Klebsiella pneumoniae
Farzand, R.; Rajakumar, K.; Barer, M. R.; Freestone, P. P. E.; Mukamolova, G.; Oggioni, M. R.; O'Hare, H.
10.1101/2020.10.07.329581 — microbiology — Posted on 2020-10-08
3378 Acute exposure to sublethal doses of neonicotinoid insecticides increases heat tolerance in honey bees
GONZALEZ, V. H.; Hranitz, J. M.; McGonigle, M. B.; Manweiler, R. E.; Smith, D. R.; Barthell, J. F.
10.1101/2020.10.07.329482 — physiology — Posted on 2020-10-08
3381 BiSulfite Bolt: A BiSulfite Sequencing Analysis Platform
Farrell, C.; Thompson, M.; Tosevska, A.; Oyetunde, A.; Pellegrini, M.
10.1101/2020.10.06.328559 — bioinformatics — Posted on 2020-10-08
3382 Effects of face masks on acoustic analysis and speech perception: Implications for peri-pandemic protocols
Magee, M.; Lewis, C.; Noffs, G.; Reece, H.; Chan, J. C. S.; Zaga, C. J.; Paynter, C.; Birchall, O.; Rojas Azocar, S.; Ediriweera, A.; Caverle, M. W.; Schultz, B. G.; Vogel, A. P.
10.1101/2020.10.06.327452 — bioengineering — Posted on 2020-10-08
3383 Natural variation of the cardiac transcriptome in humans
Domitrovic, T.; Moreira, M. H.; Carneiro, R. L.; Ribeiro-Alves, M.; Palhano, F.
10.1101/2020.10.06.328591 — genomics — Posted on 2020-10-08
3384 Automated CUT&Tag profiling of chromatin heterogeneity in mixed-lineage leukemia
Janssens, D.; Meers, M. P.; Wu, S. J.; Babaeva, E.; Meshinchi, S.; Sarthy, J. F.; Ahmad, K.; Henikoff, S.
10.1101/2020.10.06.328948 — genomics — Posted on 2020-10-08
3385 Estimating genetic nurture with summary statistics of multi-generational genome-wide association studies
Wu, Y.; Zhong, X.; Lin, Y.; Zhao, Z.; Chen, J.; Zheng, B.; Li, J. J.; Fletcher, J. M.; Lu, Q.
10.1101/2020.10.06.328724 — genetics — Posted on 2020-10-08
3387 Multiplane Mesoscope reveals distinct cortical interactions following expectation violations
Orlova, N.; Tsyboulski, D.; Najafi, F.; Seid, S.; Kivikas, S.; Kato, I.; Griffin, F.; Leon, A.; L'Heureux, Q.; North, K.; Swapp, J.; Nayan, C.; Hancock, N.; Ahmed, R.; Gelfand, E.; Cho, A.; Mace, K.; Howard, R.; Casal, L.; Lambert, S.; Lee, E. K.; Caldejon, S.; Waughman, X.; Williford, A.; Garrett, M.; Ollerenshaw, D.; Olsen, S. R.; Groblewski, P.; Lecoq, J.; Saggau, P.
10.1101/2020.10.06.328294 — neuroscience — Posted on 2020-10-08
3390 Optimal Adaptive Electrode Selection to Maximize Simultaneously Recorded Neuron Yield
Choi, J.; Kumar, K.; Khazali, M.; Wingel, K.; Choudhury, M.; Charles, A.; Pesaran, B.
10.1101/2020.10.06.328526 — neuroscience — Posted on 2020-10-08
3392 Physiological synaptic activity and recognition memory are fueled by astroglial glutamine
Cheung, G.; Bataveljic, D.; Kumar, N.; Moulard, J.; Dallerac, G.; Visser, J.; Rollenhagen, A.; Mongin, C.; Chever, O.; Bemelmans, A.; Lubke, J.; Leray, I.; Rouach, N.
10.1101/2020.10.06.328823 — neuroscience — Posted on 2020-10-08
3396 Ablation of Proliferating Osteoblast Lineage Cells After Fracture Leads to Atrophic Nonunion in a Mouse Model
Hixon, K. R.; Sykes, D. A.; Yoneda, S.; Hensley, A.; Buettmann, E. G.; Skouteris, D.; McKenzie, J. A.; Miller, A. N.; Silva, M. J.
10.1101/2020.10.06.327288 — bioengineering — Posted on 2020-10-08
3397 Compensation for the absence of the catalytically active half of DNA polymerase ε in yeast by positively selected mutations in CDC28 gene
Stepchenkova, E. I.; Zhuk, A. S.; Cui, J.; Tarakhovskaya, E. R.; Barbari, S. R.; Shcherbakova, P. V.; Polev, D. E.; Fedorov, R.; Poliakov, E.; Rogozin, I. B.; Lada, A. G.; Pavlov, Y. I.
10.1101/2020.08.27.269241 — genetics — Posted on 2020-10-08
3400 Selective translation of epigenetic modifiers drives the developmental clock of neural stem cells
Wu, Q.; Shichino, Y.; Abe, T.; Suetsugu, T.; Omori, A.; Kiyonari, H.; Iwasaki, S.; Matsuzaki, F.
10.1101/2020.10.08.330852 — developmental biology — Posted on 2020-10-08
3401 Circuit mechanisms for chemical modulation of cortex-wide network interactions and exploration behavior
Pfeffer, T.; Ponce-Alvarez, A.; Meindertsma, T.; Gahnstrom, C.; van den Brink, R. L.; Nolte, G.; Tsetsos, K.; Engel, A. K.; Deco, G.; Donner, T. H.
10.1101/2020.06.25.171199 — neuroscience — Posted on 2020-10-08
3402 Developmental effects of oxytocin neurons on social affiliation and processing of social information
Nunes, A. R.; Gliksberg, M.; Varela, S. A. M.; Teles, M.; Wircer, E.; Blechman, J.; Petri, G.; Levkowitz, G.; Oliveira, R. F.
10.1101/2020.10.08.330993 — neuroscience — Posted on 2020-10-08
3409 Evolutionary history of the Galapagos Rail revealed by ancient mitogenomes and modern samples
Chaves, J. A.; Martinez-Torres, P. J.; Depino, E. A.; Espinoza-Ulloa, S.; Garcia-Loor, J.; Beichman, A.; Stervander, M.
10.1101/2020.10.07.326983 — evolutionary biology — Posted on 2020-10-08
3411 Bacteriophage Resistance Affects Flavobacterium columnare Virulence Partly via Mutations in Genes Related to Gliding Motility and Type IX Secretion System
Kunttu, H. M.; Runtuvuori-Salmela, A.; Sundell, K.; Wiklund, T.; Middelboe, M.; Landor, L.; Ashrafi, R.; Hoikkala, V.; Sundberg, L.-R.
10.1101/2020.10.02.323337 — microbiology — Posted on 2020-10-08
3414 Microbiome-Gut-Brain-Axis communication influences metabolic switch in the mosquito Anopheles culicifacies
De, T. D.; Sharma, P.; Tevatiya, S.; Chauhan, C.; Kumari, S.; Singla, D.; Srivastava, V.; Rani, J.; Hasija, Y.; Pandey, K.; Dixit, R.
10.1101/774430 — animal behavior and cognition — Posted on 2020-10-08
3415 Single-Cell Transcriptomic Analysis Reveals Molecular Diversity of Human Oligodendrocyte Progenitor Cells
Chamling, X.; Kallman, A.; Berlinicke, C.; Devkota, P.; Mertz, J. L.; Chang, C.; Kaushik, A.; Chen, L.; Calabresi, P.; Mao, H.-Q.; Wang, J. T.-H.; Zack, D.
10.1101/2020.10.07.328971 — neuroscience — Posted on 2020-10-08
3416 Landscape of allele-specific transcription factor binding in the human genome
Abramov, S.; Boytsov, A.; Bykova, D.; Penzar, D. D.; Yevshin, I.; Kolmykov, S. K.; Fridman, M. V.; Favorov, A. V.; Vorontsov, I. E.; Baulin, E.; Kolpakov, F.; Makeev, V. J.; Kulakovskiy, I. V.
10.1101/2020.10.07.327643 — genetics — Posted on 2020-10-08
3417 The cis-regulatory effects of modern human-specific variants
Weiss, C. V.; Harshman, L.; Inoue, F.; Fraser, H. B.; Petrov, D. A.; Ahituv, N.; Gokhman, D.
10.1101/2020.10.07.330761 — evolutionary biology — Posted on 2020-10-08
3419 Anterior cingulate cortex hypofunction causes anti-social aggression in mice
van Heukelum, S.; Tulva, K.; Geers, F.; van Dulm, S.; Ruisch, H.; Mill, J.; Viana, J. F.; Beckmann, C. F.; Buitelaar, J. K.; Poelmans, G.; Glennon, J. C.; Vogt, B. A.; Havenith, M. N.; Franca, A. S. C.
10.1101/2020.10.07.328765 — neuroscience — Posted on 2020-10-08
3420 Neurophysiological network dynamics of pitch change detection.
Samiee, S.; Vuvan, D.; Florin, E.; Albouy, P.; Peretz, I.; Baillet, S.
10.1101/2020.10.07.328450 — neuroscience — Posted on 2020-10-08
3421 Evidence of hippocampal learning in human infants
Ellis, C. T.; Skalaban, L. J.; Yates, T. S.; Bejjanki, V. R.; Córdova, N. I.; Turk-Browne, N. B.
10.1101/2020.10.07.329862 — neuroscience — Posted on 2020-10-08
3422 Tractography dissection variability: what happens when 42 groups dissect 14 white matter bundles on the same dataset?
Schilling, K. G.; Rheault, F.; Petit, L.; Hansen, C. B.; Nath, V.; Yeh, F.-C.; Girard, G.; Barakovic, M.; Rafael-Patino, J.; Yu, T.; Fischi-Gomez, E.; Pizzolato, M.; Ocampo-Pineda, M.; Schiavi, S.; Canales-Rodriguez, E. J.; Daducci, A.; Granziera, C.; Innocenti, G.; Thiran, J.-P.; Mancini, L.; Wastling, S.; Cocozza, S.; Petracca, M.; Pontillo, G.; Mancini, M.; Vos, S. B.; Vakharia, V. N.; Duncan, J. S.; Melero, H.; Manzanedo, L.; Sanz-Morales, E.; Pena-Melian, A.; Calamante, F.; Attye, A.; Cabeen, R. P.; Korobova, L.; Toga, A. W.; Ambili Vijayakumari, A.; Parker, D.; Verma, R.; Radwan, A.; Sun
10.1101/2020.10.07.321083 — neuroscience — Posted on 2020-10-08
3423 A cross-species link between mTOR-related synaptic pathology and functional hyperconnectivityin autism
Pagani, M.; Bertero, A.; Trakoshis, S.; Ulysse, L.; Locarno, A.; Miseviciute, I.; De Felice, A.; Canella, C.; Supekar, K.; Galbusera, A.; Menon, V.; Tonini, R.; Deco, G.; Lombardo, M. V.; Pasqualetti, M.; Gozzi, A.
10.1101/2020.10.07.329292 — neuroscience — Posted on 2020-10-08
3424 Profiling Active Enzymes for Polysorbate Degradation in Biotherapeutics by Activity-Based Protein Profiling
Li, X.; Chandra, D.; Letarte, S.; Adam, G.; Welch, J.; Yang, R.-S.; Bodea, S.; Dow, A.; Chi, A.; Strulson, C.; Richardson, D.
10.1101/2020.10.07.330076 — bioengineering — Posted on 2020-10-08
3427 Epistasis, aneuploidy, and gain-of-function mutations underlie the evolution ofresistance to induced microtubule depolymerization
Pavani, M.; Bonaiuti, P.; Chiroli, E.; Gross, F.; Natali, F.; Macaluso, F.; Poti, A.; Pasqualato, S.; Pompei, S.; Cosentino Lagomarsino, M.; Rancati, G.; Szuts, D.; Ciliberto, A.
10.1101/2020.10.07.327759 — cell biology — Posted on 2020-10-07
3428 Polo-like kinase 1 independently controls microtubule-nucleating capacity and size of the centrosome
Ohta, M.; Zhao, Z.; Wu, D.; Wang, S.; Harrison, J. L.; Gomez-Cavazos, J. S.; Desai, A.; Oegema, K.
10.1101/2020.10.07.328740 — cell biology — Posted on 2020-10-07
3429 Abscission Checkpoint Bodies Reveal a New Facet of Abscission Checkpoint Control
Williams, L. K.; Mackay, D. R.; Whitney, M. A.; Sundquist, W. I.; Ullman, K. S.
10.1101/2020.10.07.330290 — cell biology — Posted on 2020-10-07
3431 Endoplasmic reticulum stress induces a novel Ca2+ signalling system initiated by Ca2+ microdomains
Feliziani, C.; Quassollo, G.; Holstein, D. M.; Fernadez, M.; Paton, J. C.; Paton, A. W.; Lechleiter, J. D.; Bollo, M.
10.1101/2020.10.07.328849 — cell biology — Posted on 2020-10-07
3432 Three-dimensional FIB-SEM reconstruction ofmicrotubule-organelle interaction in wholeprimary mouse beta cells
Mueller, A.; Schmidt, D.; Xu, C. S.; Pang, S.; D'Costa, J. V.; Kretschmar, S.; Muenster, C.; Kurth, T.; Jug, F.; Weigert, M.; Hess, H. F.; Solimena, M.
10.1101/2020.10.07.329268 — cell biology — Posted on 2020-10-08
3433 Depletion of voltage-dependent anion channel (VDAC) of Toxoplasma gondii affects multiple mitochondrial functions, but not calcium signalling.
Mallo, N.; dos Santos Martins Duarte, E. S.; Baehr, S. C.; Biddau, M.; Ovciarikova, J.; Wilde, M.-L.; Uboldi, A. D.; Lemgruber, L.; Tonkin, C. J.; Wideman, J. G.; Harding, C. R.; Sheiner, L.
10.1101/2020.10.07.330423 — cell biology — Posted on 2020-10-08
3434 EVALUATION OF ANTIMICROBIAL AND ANTIPROLIFERATIVE ACTIVITIES OF ACTINOBACTERIA ISOLATED FROM THE SALINE LAGOONS OF NORTHWEST PERU
Flores Clavo, R.; Ruiz Quinones, N.; Tasca Hernandez, A.; Tasca Gois Ruiz, A. L.; de Oliveira Braga, L. E.; Arce Gil, Z. L.; Serquen Lopez, L. M.; Henrique Costa, J.; Pacheco Fill, T.; Jose Salvador, M.; Fantinatti Garboggini, F.
10.1101/2020.10.07.329441 — molecular biology — Posted on 2020-10-07
3445 Miro recruits VPS13D to mitochondria
Guillen-Samander, A.; Leonzino, M.; De Camilli, P.
10.1101/2020.10.07.328906 — cell biology — Posted on 2020-10-07
3446 Genetic population subdivision of Blue Swimming Crab (Portunus pelagicus) across Indonesia inferred from mitochondrial DNA: implication to sustainable fishery
Madduppa, H.; Martaulina, R.; Zairion, Z. H.; Renjani, R. M.; Kawaroe, M.; Anggraini, N. P.; Subhan, B.; Verawati, I.; Sani, L. M. I.
10.1101/2020.10.07.329508 — molecular biology — Posted on 2020-10-07
3447 Genetic and metabolite biomarkers reveal actinobacteria-mediated estrogen biodegradation in urban estuarine sediment
Hsiao, T.-H.; Chen, Y.-L.; Meng, M.; Chuang, M.-R.; Horinouchi, M.; Hayashi, T.; Wang, P.-H.; Chiang, Y.-R.
10.1101/2020.10.07.329094 — microbiology — Posted on 2020-10-07
3449 The gut virome of healthy children during the first year of life is diverse and dynamic
Arias, C. F.; Taboada, B.; Moran, P.; Isa, P.; Serrano-Vazquez, A.; Rojas-Velazquez, L.; Perez-Juarez, H.; Lopez, S.; Torres, J.; Ximenez, C.
10.1101/2020.10.07.329565 — microbiology — Posted on 2020-10-07
3450 Miro1-dependent Mitochondrial Dynamics in Parvalbumin Interneurons
Kontou, G.; Antonoudiou, P.; Podpolny, M.; Arancibia-Carcamo, I. L.; Higgs, N. F.; Szulc, B. R.; Lopez-Domenech, G.; Salinas, P. C.; Mann, E. O.; Kittler, J. T.
10.1101/2020.10.06.328534 — neuroscience — Posted on 2020-10-07
3455 Mass spectrometry imaging of phosphatidylcholine metabolism in lungs administered with therapeutic surfactants and isotopic tracers
Ellis, S. R.; Halll, E.; Panchal, M.; Flinders, B.; Madsen, J.; Koster, G.; Heeren, R. M. A.; Clark, H. W.; Postle, A. D.
10.1101/2020.10.07.330530 — biochemistry — Posted on 2020-10-07
3458 Antisense oligonucleotide-based treatment of retinitis pigmentosa caused by USH2A exon 13 mutations
Slijkerman, R.; van Diepen, H.; Dona, M.; Venselaar, H.; Zang, J.; Neuhauss, S.; Peters, T.; Broekman, S.; Pennings, R.; Kremer, H.; Adamson, P.; de Vrieze, E.; van Wijk, E.
10.1101/2020.10.06.320499 — genetics — Posted on 2020-10-07
3461 BATHYARCHAEOTA OCCURRENCE IN SHALLOW MARINE METHANE-RICH SEDIMENTS (SACO DO MAMANGUA, RIO DE JANEIRO, BRAZIL)
Romano, R. G.; Bendia, A. G.; Franco, D. C.; Signori, C. N.; Yu, T.; Wang, F.; Jovane, L.; Pellizari, V. H.
10.1101/2020.10.07.329656 — microbiology — Posted on 2020-10-07
3466 Genetic requirements for cell division in a genomically minimal cell
Pelletier, J. F.; Sun, L.; Wise, K. S.; Assad-Garcia, N.; Karas, B. J.; Deerinck, T. J.; Ellisman, M. H.; Mershin, A.; Gershenfeld, N.; Chuang, R.-Y.; Glass, J. I.; Strychalski, E. A.
10.1101/2020.10.07.326892 — synthetic biology — Posted on 2020-10-07
3467 Targeting hypoxic habitats with hypoxia pro-drug evofosfamide in preclinical models of sarcoma
Jardim Perassi, B. V.; Mu, W.; Huang, S.; Tomaszewski, M. R.; Poleszczuk, J.; Abdalah, M. A.; Budzevich, M. M.; Dominguez-Viqueira, W.; Reed, D. R.; Bui, M. M.; Johnson, J. O.; Martinez, G. V.; Gillies, R. J.
10.1101/2020.10.06.326934 — cancer biology — Posted on 2020-10-07
3468 Spatially resolved optical monitoring of spinal cord blood flow with a minimally invasive, multi-level epidural probe
Busch, D. R.; Lin, W.; Goh, C. C.; Gao, F.; Larson, N. G.; Wahl, J.; Bilfinger, T.; Yodh, A. G.; Floyd, T. F.
10.1101/2020.10.06.326900 — bioengineering — Posted on 2020-10-07
3469 Detection of a bedaquiline / clofazimine resistance reservoir in Mycobacterium tuberculosis predating the antibiotic era
van Dorp, L.; Nimmo, C.; Torres Ortiz, A.; Pang, J.; Acman, M.; Tan, C. C.; Millard, J.; Padayatchi, N.; Grant, A.; O'Donnell, M. R.; Pym, A.; Brynildsrud, O. B.; Eldholm, V.; Grandjean, L.; Didelot, X.; Balloux, F.
10.1101/2020.10.06.328799 — genomics — Posted on 2020-10-07
3470 Thousands of previously unknown phages discovered in whole-community human gut metagenomes
Benler, S.; Yutin, N.; Antipov, D.; Raykov, M.; Shmakov, S. A.; Gussow, A. B.; Pevzner, P. A.; Koonin, E. V.
10.1101/2020.10.07.330464 — microbiology — Posted on 2020-10-07
3471 MiSiC, a general deep learning-based method for the high-throughput cell segmentation of complex bacterial communities
Panigrahi, S.; Murat, D.; Le Gall, A.; Martineau, E.; Goldlust, K.; Fiche, J.-B.; Rombouts, S.; Nollmann, M.; Espinosa, L.; Mignot, T.
10.1101/2020.10.07.328666 — microbiology — Posted on 2020-10-07
3472 Meta-transcriptomic identification of divergent Amnoonviridae in fish
Turnbull, O. M. H.; Ortiz-Baez, A. S.; Eden, J.-S.; Shi, M.; Williamson, J. E.; Gaston, T. F.; Zhang, Y.-Z.; Holmes, E. C.; Geoghegan, J. L.
10.1101/2020.10.06.329003 — microbiology — Posted on 2020-10-07
3473 Blocking of EGFR Signaling is a Latent Strategy for the Improvement of Prognosis of HPV Induced Cancer
Qiu, J.; Hu, F.; Shao, T.; Guo, Y.; Dai, Z.; Nie, H.; Olasunkanmi, O. I.; Chen, Y.; Lin, L.; Zhao, W.; Zhong, Z.; Wang, Y.
10.1101/2020.10.06.329110 — microbiology — Posted on 2020-10-07
3474 Deploying and in vitro gut model to assay the impact of a mannan-oligosaccharide prebiotic, Bio-MOS(R) on the Atlantic salmon (Salmo salar) gut microbiome.
Kazlauskaite, R.; Cheaib, B.; Humble, J.; Heys, C.; Ijaz, U. Z.; Connelly, S.; Sloan, W. T.; Russell, J.; Martinez-Rubio, L.; Sweetman, J.; Kitts, A.; McGinnity, P.; Lyons, P.; Llewellyn, M.
10.1101/2020.10.07.328427 — microbiology — Posted on 2020-10-07
3475 A pair of effectors encoded on a conditionally dispensable chromosome of Fusarium oxysporum suppress host-specific immunity
Ayukawa, Y.; Asai, S.; Gan, P.; Tsushima, A.; Ichihashi, Y.; Shibata, A.; Komatsu, K.; Houterman, P. M.; Rep, M.; Shirasu, K.; Arie, T.
10.1101/2020.10.06.329052 — microbiology — Posted on 2020-10-07
3476 Umbilical cord blood derived microglia-like cells to model COVID-19 exposure
Perlis, R. H.; Edlow, A. G.; Sheridan, S. D.; Thanos, J. M.; De Guzman, R. M.; McCrea, L. T.; Horng, J. E.; Fu, T.; Sellgren, C. M.
10.1101/2020.10.07.329748 — neuroscience — Posted on 2020-10-07
3478 Peptide-based Inhibitors of Protein-Protein Interactions of Src Homology 2 Domain-Containing Phosphatase 2
Bobone, S.; Pannone, L.; Biondi, B.; Solman, M.; Flex, E.; Canale, V.; Calligari, P.; De Faveri, C.; Gandini, T.; Quercioli, A.; Torini, G.; Venditti, M.; Lauri, A.; Fasano, G.; Hoeksma, J.; Santucci, V.; Cattani, G.; Bocedi, A.; Carpentieri, G.; Tirelli, V.; Sanchez, M.; Peggion, C.; Formaggio, F.; Den Hertog, J.; Martinelli, S.; Bocchinfuso, G.; Tartaglia, M.; Stella, L.
10.1101/2020.08.28.271809 — biophysics — Posted on 2020-10-07
3480 NSP 11 of SARS-CoV-2 is an Intrinsically Disordered Protein
Gadhave, K.; Kumar, P.; Kumar, A.; Bhardwaj, T.; Garg, N.; Giri, R.
10.1101/2020.10.07.330068 — biochemistry — Posted on 2020-10-07
3482 Swimming direction of the glass catfish is responsive to magnetic stimulation
Hunt, R. D.; Ashbaugh, R. C.; Reimers, M.; Udpa, L.; Saldana De Jimenez, G.; Moore, M.; Gilad, A. A.; Pelled, G.
10.1101/2020.08.13.250035 — animal behavior and cognition — Posted on 2020-10-07
3484 Gene-rich X chromosomes implicate intragenomic conflict in the evolution of bizarre genetic systems
Anderson, N.; Jaron, K. S.; Hodson, C. N.; Couger, M. B.; Sevcik, J.; Pirro, S.; Ross, L.; Roy, S. W.
10.1101/2020.10.04.325340 — evolutionary biology — Posted on 2020-10-07
3485 Toward a Monte Carlo Approach to Selecting Climate Variables in MaxEnt: A Case Study Using Cassin's Sparrow (Peucaea cassinii)
Schnase, J. L.; Carroll, M. L.; Gill, R. L.; Tamkin, G. S.; Li, J.; Strong, S. L.; Maxwell, T. P.; Aronne, M. E.
10.1101/2020.07.15.202945 — ecology — Posted on 2020-10-07
3486 A mathematical framework for dissecting the normative foundations of conservation decisions
Latombe, G.; Lenzner, B.; Schertler, A.; Dullinger, S.; Glaser, M.; Jaric, I.; Pauchard, A.; Wilson, J. R. U.; Essl, F.
10.1101/2020.09.04.282947 — ecology — Posted on 2020-10-07
3487 Human Naive Epiblast Cells Possess Unrestricted Lineage Potential
Guo, G.; Stirparo, G. G.; Strawbridge, S.; Spindlow, D.; Yang, J.; Clarke, J.; Dattani, A.; Yanagida, A.; Li, M. A.; Myers, S.; Ozel, B. N.; Nichols, J.; Smith, A.
10.1101/2020.02.04.933812 — developmental biology — Posted on 2020-10-07
3488 Architecture of the Tuberous Sclerosis Protein Complex
Ramlaul, K.; Fu, W.; Li, H.; de Martin Garrido, N.; He, L.; Cui, W.; Aylett, C. H. S.; Wu, G.
10.1101/2020.09.29.319707 — cell biology — Posted on 2020-10-07
3489 Bacterial Swarmers exhibit a Protective Response to Intestinal Stress
Chen, W.; De, A.; Li, H.; Wright, J. R.; Lamendella, R.; Lukin, D. J.; Szymczak, W.; Sun, K.; Kelly, L.; Ghosh, S.; Kearns, D. B.; He, Z.; Jobin, C.; Luo, X.; Byju, A.; Chatterjee, S.; Yeoh, B. S.; Vijay-Kumar, M.; Tang, J. X.; Mani, S.
10.1101/759886 — microbiology — Posted on 2020-10-07
3490 Aβ induces acute oxidative stress leading to brain glucose hypometabolism and hyperactivity in Alzheimer's disease pathogenesis
Malkov, A.; Popova, I.; Ivanov, A.; Jang, S.-S.; Yoon, S. Y.; Osipov, A.; Huang, Y.; Zilberter, Y.; Zilberter, M.
10.1101/2020.08.12.248492 — neuroscience — Posted on 2020-10-07
3495 Convergent and distributed effects of the schizophrenia-associated 3q29 deletion on the human neural transcriptome
Sefik, E.; Purcell, R. H.; The Emory 3q29 Project, ; Walker, E. F.; Bassell, G. J.; Mulle, J. G.
10.1101/2020.05.25.111351 — genetics — Posted on 2020-10-07
3496 Eukaryotic virus composition can predict the efficiency of carbon export in the global ocean
Kaneko, H.; Blanc-Mathieu, R.; Endo, H.; Chaffron, S.; Delmont, T. O.; Gaia, M.; Henry, N.; Hernandez Velazquez, R.; Nguyen, C. H.; Mamitsuka, H.; Forterre, P.; Jaillon, O.; de Vargas, C.; Sullivan, M. B.; Suttle, C. A.; Guidi, L.; Ogata, H.
10.1101/710228 — ecology — Posted on 2020-10-07
3500 Generalization in data-driven models of primary visual cortex
Lurz, K.-K.; Bashiri, M.; Willeke, K. F.; Jagadish, A. K.; Wang, E.; Walker, E. Y.; Cadena, S.; Muhammad, T.; Cobos, E.; Tolias, A.; Ecker, A.; Sinz, F.
10.1101/2020.10.05.326256 — neuroscience — Posted on 2020-10-07
3503 Targeting the SHP2 phosphatase promotes vascular damage and inhibition of tumor growth
Wang, Y.; Salvucci, O.; Ohnuki, H.; Tran, A. D.; Ha, T.; Feng, J.-X.; DiPrima, M.; Kwak, H.; Wang, D.; Kruhlak, M.; Tosato, G.
10.1101/2020.10.06.327882 — cancer biology — Posted on 2020-10-07
3507 Otx2 stimulates adult retinal ganglion cell regeneration.
Torero-Ibad, R.; Quenech'du, N.; Prochiantz, A.; Moya, K. L.
10.1101/2020.10.06.327999 — neuroscience — Posted on 2020-10-07
3510 Phase-locking of resting-state brain networks with the gastric basal electrical rhythm
Choe, A. S.; Tang, B.; Smith, K. R.; Honari, H.; Lindquist, M. A.; Caffo, B. S.; Pekar, J. J.
10.1101/2020.10.06.328054 — neuroscience — Posted on 2020-10-07
3513 Variable optical properties of light-harvesting complex II revisited
Iwai, M.; Chen, J.-J.; Park, S.; Yoneda, Y.; Schmid, E. M.; Fletcher, D. A.; Fleming, G. R.; Niyogi, K. K.
10.1101/2020.10.05.312405 — plant biology — Posted on 2020-10-07
3515 Formation of flavone-based wooly fibres by glandular trichomes of Dionysia tapetodes.
Bourdon, M.; Gaynord, J.; Muller, K.; Evans, G.; Wallis, S.; Aston, P.; Spring, D. R.; Wightman, R.
10.1101/2020.10.06.320911 — plant biology — Posted on 2020-10-07
3519 MultiPhATE2: Code for Functional Annotation and Comparison of Bacteriophage Genomes
Zhou, C. E.; Kimbrel, J.; Edwards, R. A.; McNair, K.; Souza, B. A.; Malfatti, S.
10.1101/2020.10.05.324566 — bioinformatics — Posted on 2020-10-07
3528 Temperature increases soil respiration across ecosystem types and soil development, but soil properties determine the magnitude of this effect
Dacal, M.; Delgado-Baquerizo, M.; Barquero, J.; Berhe, A. A.; Gallardo, A.; Maestre, F. T.; Garcia-Palacios, P.
10.1101/2020.10.06.327973 — ecology — Posted on 2020-10-07
3529 The short and long-range RNA-RNA Interactome of SARS-CoV-2
Ziv, O.; Price, J.; Shalamova, L.; Kamenova, T.; Goodfellow, I.; Weber, F.; Miska, E. A.
10.1101/2020.07.19.211110 — molecular biology — Posted on 2020-10-07
3530 Dynamic and reversible remapping of network representations in an unchanging environment
Low, I. I. C.; Williams, A. H.; Campbell, M. G.; Linderman, S. W.; Giocomo, L. M.
10.1101/2020.10.05.326942 — neuroscience — Posted on 2020-10-07
3532 Modulating the Blood-Brain Barrier by Light Stimulation of Molecular-Targeted Nanoparticles
Li, X.; Vemireddy, V.; Cai, Q.; Xiong, H.; Kang, P.; Li, X.; Giannotta, M.; Hayenga, H.; Pan, E.; Sirsi, S.; Mateo, C.; Kleinfeld, D.; Greene, C.; Campbell, M.; Dejana, E.; Bachoo, R.; Qin, Z.
10.1101/2020.10.05.326843 — neuroscience — Posted on 2020-10-07
3534 Distinctive alteration of presynaptic proteins in the outer molecular layer of the dentate gyrus in Alzheimer's disease
Haytural, H.; Jorda-Siquier, T.; Winblad, B.; Mulle, C.; Tjernberg, L. O.; Granholm, A.-C.; Frykman, S.; Barthet, G.
10.1101/2020.10.06.327833 — neuroscience — Posted on 2020-10-07
3538 MFG-E8 Signaling Promotes Elastolysis and Calcification in the Aging Aortic Wall
Kim, S. H.; Liu, L.; Ni, L.; Zhang, L.; Zhang, J.; Wang, Y.; McGraw, K. R.; Monticone, R. E.; Telljohann, R.; Lakatta, E. G.; Wang, M.
10.1101/2020.10.05.326728 — pathology — Posted on 2020-10-07
3539 Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes
Krichel, B.; Bylapudi, G.; Schmidt, C.; Blanchet, C.; Schubert, R.; Brings, L.; Koehler, M.; Zenobi, R.; Svergun, D.; Lorenzen, K.; Madhugiri, R.; Ziebuhr, J.; Uetrecht, C.
10.1101/2020.09.30.320762 — biophysics — Posted on 2020-10-07
3540 Steric Interactions at Gln154 in ZEITLUPE Induce Reorganization of the LOV Domain Dimer Interface
Pudasaini, A.; Green, R.; Song, Y. H.; Blumenfeld, A.; Karki, N.; Imaizumi, T.; Zoltowski, B. D.
10.1101/2020.10.05.326595 — biophysics — Posted on 2020-10-07
3541 Spike protein mutational landscape in India: Could Mullers ratchet be a future game-changer for COVID-19?
Banerjee, R.; Basak, K.; Ghosh, A.; Rajachandran, V.; Sureka, K.; Ganguly, D.; Chattopadhyay, S.
10.1101/2020.08.18.255570 — bioinformatics — Posted on 2020-10-07
3546 Selection on ancestral genetic variation fuels parallel ecotype formation in bottlenose dolphins
Louis, M.; Galimberti, M.; Archer, F.; Berrow, S.; Brownlow, A. C.; Fallon, R.; Nykanen, M.; O'Brien, J.; Robertson, K. M.; Rosel, P. E.; Simon-Bouhet, B.; Wegmann, D.; Fontaine, M. C.; Foote, A. D.; Gaggiotti, O. E.
10.1101/2020.10.05.325159 — evolutionary biology — Posted on 2020-10-07
3547 Model-based ordination for species with unequal niche widths
van der Veen, B.; Hui, F. K. C.; Hovstad, K. A.; Solbu, E. B.; O'Hara, R. B.
10.1101/2020.10.05.326199 — ecology — Posted on 2020-10-07
3551 Making the invisible enemy visible
Croll, T.; Diederichs, K.; Fischer, F.; Fyfe, C.; Gao, Y.; Horrell, S.; Joseph, A. P.; Kandler, L.; Kippes, O.; Kirsten, F.; Müller, K.; Nolte, K.; Payne, A.; Reeves, M. G.; Richardson, J.; Santoni, G.; Stäb, S.; Tronrud, D.; Williams, C.; Thorn, A.
10.1101/2020.10.07.307546 — molecular biology — Posted on 2020-10-07
3553 Extremely potent human monoclonal antibodies from convalescent Covid-19 patients
Andreano, E.; Nicastri, E.; Paciello, I.; Pileri, P.; Manganaro, N.; Piccini, G.; Manenti, A.; Pantano, E.; Kabanova, A.; Troisi, M.; Vacca, F.; Cardamone, D.; De Santi, C.; Benincasa, L.; Agrati, C.; Capobianchi, M. R.; Castilletti, C.; Emiliozzi, A.; Fabbiani, M.; Montagnani, F.; Depau, L.; Brunetti, J.; Bracci, L.; Montomoli, E.; Sala, C.; Ippolito, G.; Rappuoli, R.
10.1101/2020.10.07.328302 — immunology — Posted on 2020-10-07
3554 Automated Reconstruction of a Serial-Section EM Drosophila Brain with Flood-Filling Networks and Local Realignment
Li, P. H.; Lindsey, L. F.; Januszewski, M.; Zheng, Z.; Bates, A. S.; Taisz, I.; Tyka, M.; Nichols, M.; Li, F.; Perlman, E.; Maitin-Shepard, J.; Blakely, T.; Leavitt, L.; Jefferis, G. S. X. E.; Bock, D.; Jain, V.
10.1101/605634 — neuroscience — Posted on 2020-10-07
3556 SARS-CoV-2 Simulations Go Exascale to Capture Spike Opening and Reveal Cryptic Pockets Across the Proteome
Zimmerman, M. I.; Porter, J. R.; Ward, M. D.; Singh, S.; Vithani, N.; Meller, A.; Mallimadugula, U. L.; Kuhn, C. E.; Borowsky, J. H.; Wiewiora, R. P.; Hurley, M. F. D.; Harbison, A. M.; Fogarty, C. A.; Coffland, J. E.; Fadda, E.; Voelz, V. A.; Chodera, J. D.; Bowman, G. R.
10.1101/2020.06.27.175430 — biophysics — Posted on 2020-10-07
3557 MAJORA: Continuous integration supporting decentralised sequencing for SARS-CoV-2 genomic surveillance
Nicholls, S. M.; Poplawski, R.; Bull, M. J.; Underwood, A.; Chapman, M.; Abu-Dahab, K.; Taylor, B.; Jackson, B.; Rey, S.; Amato, R.; Livett, R.; Goncalves, S.; Harrison, E. M.; Peacock, S. J.; Aanensen, D. M.; Rambaut, A.; Connor, T. R.; Loman, N. J.; The COVID-19 Genomics UK Consortium (COG-UK),
10.1101/2020.10.06.328328 — bioinformatics — Posted on 2020-10-07
3559 Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2
Azouz, N. P.; Klingler, A. M.; Callahan, V.; Akhrymuk, I. V.; Elez, K.; Raich, L.; Henry, B. M.; Benoit, J. L.; Benoit, S. W.; Noe, F.; Kehn-Hall, K.; Rothenberg, M. E.
10.1101/2020.05.04.077826 — microbiology — Posted on 2020-10-07
3560 Single-Cell Analysis of Hyperthermic Intraperitoneal Chemotherapy Treated Tumors Reveals Distinct Cellular and Molecular Responses
Horowitz, M. P.; Alali, Z.; Alban, T.; Hong, C.; Esakov, E.; Hwang, T. H.; Lathia, J.; Michener, C. M.; DeBernardo, R.; Reizes, O.
10.1101/2020.10.05.326710 — cancer biology — Posted on 2020-10-07
3562 Taxonomic hypotheses and the biogeography of speciation in the Tiger Whiptail complex (Aspidoscelis tigris: Squamata, Teiidae)
Chafin, T. K.; Douglas, M. R.; Anthonysamy, W. J. B.; Sullivan, B. K.; Walker, J. M.; Cordes, J. E.; Douglas, M. E.
10.1101/2020.10.05.327270 — evolutionary biology — Posted on 2020-10-07
3563 Diffusion MRI Changes in the Healthy Aging Canine Brain
Barry, E. F.; Loftus, J. P.; Luh, W.-M.; de Leon, M. J.; Niogi, S. N.; Johnson, P. J.
10.1101/2020.10.05.327205 — neuroscience — Posted on 2020-10-07
3564 In vivo human whole-brain Connectom diffusion MRI dataset at 760 μm isotropic resolution
Wang, F.; Dong, Z.; Tian, Q.; Liao, C.; Fan, Q.; Hoge, W. S.; Keil, B.; Polimeni, J. R.; Wald, L. L.; Huang, S. Y.; Setsompop, K.
10.1101/2020.10.05.327395 — neuroscience — Posted on 2020-10-07
3567 Moving toward generalizable NZ-1 labeling for 3D structure determination with optimized epitope tag insertion
Tamura-Sakaguchi, R.; Aruga, R.; Hirose, M.; Ekimoto, T.; Miyake, T.; Hizukuri, Y.; Oi, R.; Kaneko, M. K.; Kato, Y.; Akiyama, Y.; Ikeguchi, M.; Iwasaki, K.; Nogi, T.
10.1101/2020.10.06.325969 — biophysics — Posted on 2020-10-07
3568 Dimerization of a membrane transporter is driven by differential energetics of lipid solvation of dissociated and associated states
Chadda, R.; Bernhardt, N.; Kelley, E. G.; Teixeira, S. C. M.; Griffith, K.; Gil-Ley, A.; Ozturk, T. N.; Hughes, L. E.; Forsythe, A.; Krishnamani, V.; Faraldo-Gomez, J.; Robertson, J. L.
10.1101/2020.10.05.327239 — biophysics — Posted on 2020-10-07
3569 Glycan-induced protein dynamics in human norovirus P dimers depend on virus strain and deamidation status
Duelfer, J.; Yan, H.; Brodmerkel, M. N.; Creutznacher, R.; Mallagaray, A.; Peters, T.; Caleman, C.; Marklund, E. G.; Uetrecht, C.
10.1101/2020.10.07.329623 — biophysics — Posted on 2020-10-07
3573 Dominant monoallelic variant in the PAK2 gene causes Knobloch syndrome type 2
Antonarakis, S. E.; Holoubek, A.; Rapti, M.; Rademaker, J.; Meylan, J.; Iwaszkiewicz, J.; Zoete, V.; Ansar, M.; BOREL, C. c.; Menzel, O.; Kuzelova, K.; Santoni, F. A.
10.1101/2020.10.06.328419 — genetics — Posted on 2020-10-07
3575 The Species-specific Acquisition and Diversification of a Novel Family of Killer Toxins in Budding Yeasts of the Saccharomycotina.
Fredericks, L. R.; Lee, M. D.; Crabtree, A. M.; Boyer, J. M.; Kizer, E. A.; Taggart, N. T.; Hunter, S. S.; Kennedy, C. B.; Willmore, C. G.; Tebbe, N. M.; Harris, J. S.; Brocke, S. N.; Rowley, P. A.
10.1101/2020.10.05.322909 — genetics — Posted on 2020-10-07
3576 The transcription factor BCL11A defines a distinctive subset of dopamine neurons in the developing and adult midbrain
Tolve, M.; Ulusoy, A.; Islam, K. U. S.; Bodea, G. O.; Öztürk, E.; Broske, B.; Mentani, A.; Wagener, A.; van Loo, K.; Britsch, S.; Liu, P.; T. Khaled, W.; Baader, S. L.; Di Monte, D. A.; Blaess, S.
10.1101/2020.10.06.327940 — developmental biology — Posted on 2020-10-07
3579 Salmonella enterica serovar Typhimurium SPI-1 and SPI-2 shape the transcriptional landscape of epithelial cells in a human intestinal organoid model system
Lawrence, A.-L. E.; Abuaita, B. H.; Berger, R. P.; Hill, D. R.; Huang, S.; Yadagiri, V. K.; Bons, B.; Fields, C.; Wobus, C. E.; Spence, J. R.; Young, V. B.; O'Riordan, M.
10.1101/2020.10.05.327551 — microbiology — Posted on 2020-10-07
3580 Microscopy-based assay for semi-quantitative detection of SARS-CoV-2 specific antibodies in human sera
Pape, C.; Remme, R.; Wolny, A.; Olberg, S.; Wolf, S.; Cerrone, L.; Cortese, M.; Klaus, S.; Lucic, B.; Ullrich, S.; Anders-Össwein, M.; Wolf, S.; Berati, C.; Neufeldt, C. J.; Ganter, M.; Schnitzler, P.; Merle, U.; Lusic, M.; Boulant, S.; Stanifer, M.; Bartenschlager, R.; Hamprecht, F. A.; Kreshuk, A.; Tischer, C.; Kräusslich, H.-G.; Müller, B.; Laketa, V.
10.1101/2020.06.15.152587 — microbiology — Posted on 2020-10-07
3582 Spatial distribution of neuropathology and neuroinflammation elucidate the biomechanics of fluid percussion injury
Beitchman, J. A.; Lifshitz, J.; Harris, N. G.; Thomas, T. C.; Lafrenaye, A. D.; Hanell, A.; Dixon, C. E.; Povlishock, J. T.; Rowe, R. K.
10.1101/2020.10.05.325514 — neuroscience — Posted on 2020-10-07
3583 A novel female-specific circadian clock mechanism regulating metabolism
Mekbib, T.; Suen, T.-C.; Rollins-Hairston, A.; Smith, K.; Armstrong, A.; Gray, C.; Baba, K.; Baggs, J.; Ehlen, J. C.; Tosini, G.; DeBruyne, J.
10.1101/2020.10.05.326652 — physiology — Posted on 2020-10-07
3585 Dissecting phenotypic transitions in metastatic disease via photoconversion-based isolation
Sela, Y.; Li, J.; Kuri, P.; Merrell, A.; Li, N.; Lengner, C.; Rompolas, P.; Stanger, B.
10.1101/2020.10.05.327213 — cancer biology — Posted on 2020-10-07
3587 Causal evidence for the adaptive benefits of social foraging in the wild
Snijders, L.; Krause, S.; Tump, A. N.; Breuker, M.; Ortiz, C.; Rizzi, S.; Ramnarine, I. W.; Krause, J.; Kurvers, R. H. J. M.
10.1101/2020.08.17.254250 — animal behavior and cognition — Posted on 2020-10-07
3588 Sex differences in the human brain transcriptome of cases with schizophrenia
Hoffman, G. E.; Ma, Y.; Montgomery, K. S.; Bendl, J.; Jaiswal, M. K.; Kozlenkov, A. K.; CommonMind Consortium, ; Peters, M. A.; Dracheva, S.; Fullard, J. F.; Chess, A.; Devlin, B.; Sieberts, S. K.; Roussos, P.
10.1101/2020.10.05.326405 — genomics — Posted on 2020-10-07
3590 System-level analyses of keystone genes required for mammalian tooth development
Hallikas, O.; Das Roy, R.; Christensen, M. M.; Renvoise, E.; Sulic, A.-M.; Jernvall, J.
10.1101/869065 — developmental biology — Posted on 2020-10-07
3592 Endogenous Rab29 does not impact basal or nigericin and monensin stimulated LRRK2 pathway activity
Kalogeropulou, A. F.; Freemantle, J. B.; Lis, P.; Vides, E. G.; Polinski, N. K.; Alessi, D. R.
10.1101/2020.06.08.139675 — neuroscience — Posted on 2020-10-07
3593 Ectoderm to mesoderm transition by downregulation of actomyosin contractility
Kashkooli, L.; Rozema, D.; Espejo-Ramirez, L.; Lasko, P.; Fagotto, F.
10.1101/870444 — cell biology — Posted on 2020-10-07
3596 A mouse model of Bardet-Biedl Syndrome has impaired fear memory, which is rescued by lithium treatment
Pak, T. K.; Carter, C. S.; Zhang, Q.; Huang, S. C.; Searby, C.; Hsu, Y.; Taugher, R.; Vogel, T.; Cychosz, C. C.; Genova, R.; Moreira, N.; Stevens, H.; Wemmie, J.; Pieper, A. A.; Wang, K. K.; Sheffield, V. C.
10.1101/2020.10.06.322883 — animal behavior and cognition — Posted on 2020-10-07
3599 Persistence as an optimal hedging strategy
Browning, A. P.; Sharp, J. A.; Mapder, T.; Baker, C. M.; Burrage, K.; Simpson, M. J.
10.1101/2019.12.19.883645 — systems biology — Posted on 2020-10-07
3600 Characters of neoantigens in cancer immunotherapy
Bai, P.; Li, Y.; Zhou, Q.; Xia, J.; Wu, M.; Deng, H.; Kappler, J. W.; Marrack, P.; Zhou, Y.; Yin, L.
10.1101/700732 — cancer biology — Posted on 2020-10-07
3601 The role of cytosolic polyadenylation element binding protein 2 alternative splicing in hypoxia
Mayo, E. M.; Stevens, S. C.; Ali, A. N.; Moss, C. J.; Lund, S. P.; Nazario-Munoz, G. S.; Chalfant, C. E.; Park, M. A.
10.1101/2020.10.05.325290 — cell biology — Posted on 2020-10-06
3603 APEX-Gold: A genetically-encoded particulate marker for robust 3D electron microscopy
Rae, J.; Ferguson, C.; Ariotti, N.; Webb, R.; Cheng, H.-H.; Mead, J.; Riches, J.; Hunter, D.; Martel, N.; Baltos, J.; Christopoulos, A.; Bryce, N.; Cagigas, M.; Fonseka, S.; Hardeman, E.; Gunning, P.; Gambin, Y.; Hall, T. E.; Parton, R. G.
10.1101/2020.10.06.328831 — cell biology — Posted on 2020-10-06
3605 Structure of the Mammalian Mediator
Zhao, H.; Young, N.; Kalchschmidt, J.; Lieberman, J.; El Khattabi, L.; Casellas, R.; Asturias, F. J.
10.1101/2020.10.05.326918 — cell biology — Posted on 2020-10-06
3613 The guidance and adhesion protein FLRT2 dimerizes in cis via dual Small-X3-Small transmembrane motifs
Jackson, V.; Hermann, J.; Tynan, C. J.; Rolfe, D. J.; Kalli, A. C.; Duncan, A. L.; Jones, E. Y.; Sansom, M.; Martin-Fernandez, M. L.; Seiradake, E.; Chavent, M.
10.1101/2020.10.06.328401 — biophysics — Posted on 2020-10-06
3615 Sub-second heat inactivation of coronavirus
Jiang, Y.; Zhang, H.; Wippold, J. A.; Gupta, J.; Dai, J.; de Figueiredo, P.; Leibowitz, J. L.; Han, A.
10.1101/2020.10.05.327528 — bioengineering — Posted on 2020-10-06
3619 Plectin Ensures Intestinal Epithelial Integrity and Protects Colon Against Colitis
Krausova, A.; Buresova, P.; Sarnova, L.; Oyman-Eyrilmez, G.; Skarda, J.; Wohl, P.; Bajer, L.; Sticova, E.; Bartonova, L.; Pacha, J.; Koubkova, G.; Prochazka, J.; Spoerrer, M.; Duerrbeck, C.; Stehlikova, Z.; Vit, M.; Ziolkowska, N.; Sedlacek, R.; Jirak, D.; Kverka, M.; Wiche, G.; Fabry, B.; Korinek, V.; Gregor, M.
10.1101/2020.10.06.323493 — molecular biology — Posted on 2020-10-06
3620 Globally defining the effects of mutations in a picornavirus capsid
Mattenberger, F.; Latorre, V.; Tirosh, O.; Stern, A.; Geller, R.
10.1101/2020.10.06.327916 — microbiology — Posted on 2020-10-06
3621 A three-dimensional Air-Liquid Interface Culture Model for the Study of Epstein-Barr virus Infection in the Nasopharynx
Ziegler, P.; Bai, Y.; Tian, Y.; Abrahamsson, S.; Green, A.; Moore, J.; Lee, S. E.; Myerburg, M. M.; Park, H. J.; Tang, K.-W.; Shair, K. H. Y.
10.1101/2020.08.31.272096 — microbiology — Posted on 2020-10-06
3624 SARS-CoV-2 infection damages airway motile cilia and impairs mucociliary clearance
Robinot, R.; Hubert, M.; Dias de Melo, G.; Lazarini, F.; Bruel, T.; Smith, N.; Levallois, S.; Larrous, F.; Fernandes, J.; Gellenoncourt, S.; Rigaud, S.; Gorgette, O.; Thouvenot, C.; Trebeau, C.; Dumenil, G.; Mallet, A.; Gobaa, S.; Etournay, R.; Lledo, P.-M.; Lecuit, M.; Bourhy, H.; Duffy, D.; Michel, V.; Schwartz, O.; Chakrabarti, L. A.
10.1101/2020.10.06.328369 — microbiology — Posted on 2020-10-06
3625 Vaccination reshapes the virus-specific T cell repertoire in unexposed adults
Pan, Y.-G.; Aiamkitsumrit, B.; Bartolo, L.; Wang, Y.; Lavery, C.; Marc, A.; Holec, P. V.; Rappazzo, C. G.; Eilola, T.; Gimotty, P. A.; Hensley, S. E.; Antia, R.; Zarnitsyna, V. I.; Birnbaum, M. E.; Su, L. F.
10.1101/2020.10.01.322958 — immunology — Posted on 2020-10-06
3627 The mouse cortico-basal ganglia-thalamic network
Foster, N. N.; Korobkova, L.; Garcia, L.; Gao, L.; Becerra, M.; Sherafat, Y.; Peng, B.; Li, X.; Choi, J.-H.; Gou, L.; Zingg, B.; Azam, S.; Lo, D.; Khanjani, N.; Zhang, B.; Stanis, J.; Bowman, I.; Cotter, K.; Cao, C.; Yamashita, S.; Tugangui, A.; Li, A.; Jiang, T.; Jia, X.; Feng, Z.; Aquino, S.; Dan, G.; Fayzullina, M.; Mun, H.-S.; Ustrell, S.; Boesen, T.; Santarelli, A.; Zhu, M.; Benavidez, N. L.; Song, M.; Johnson, D. L.; Xu, H.; Bienkowski, M. S.; Yang, X. W.; Gong, H.; Wickersham, I.; Luo, Q.; Lim, B. K.; Zhang, L. I.; Hintiryan, H.; Dong, H.
10.1101/2020.10.06.326876 — neuroscience — Posted on 2020-10-06
3631 PHENSIM: Phenotype Simulator
Alaimo, S.; Rapicavoli, R. V.; Marceca, G. P.; La Ferlita, A.; Serebrennikova, O. B.; Tsichlis, P. N.; Mishra, B.; Pulvirenti, A.; Ferro, A.
10.1101/2020.01.20.912279 — bioinformatics — Posted on 2020-10-06
3637 Structural basis for repurposing a 100-years-old drug suramin for treating COVID-19
Yin, W.; Luan, X.; Li, Z.; Zhang, L.; Zhou, Z.; Gao, M.; Wang, X.; Zhou, F.; Shi, J.; You, E.; Liu, M.; Wang, Q.; Wang, Q.; Jiang, Y.; Jiang, H.; Xiao, G.; Yu, X.; Zhang, S.; Xu, H. E.
10.1101/2020.10.06.328336 — molecular biology — Posted on 2020-10-06
3638 Edition of complex gene families in tobacco with GoldenBraid 4.0, a multipurpose web-based platform for plant genome engineering
Vazquez-Vilar, M.; Garcia-Carpintero, V.; Selma, S.; Bernabe-Orts, J. M.; Sanchez-Vicente, J.; Salazar-Sarasua, B.; Ressa, A.; de Paola, C.; Ajenjo, M.; Fernandez-del-Carmen, A.; Granell, A.; Orzaez, D.
10.1101/2020.10.06.327841 — molecular biology — Posted on 2020-10-06
3640 LncRNAs interacting with the translation machinery contribute to human neuronal differentiation.
Douka, K.; Birds, I.; Wang, D.; Clayton, S.; Byford, A.; Vasconcelos, E. J. R.; O'Connell, M. J.; Deuchars, J.; Whitehouse, A.; Aspden, J. L.
10.1101/2020.10.01.321919 — molecular biology — Posted on 2020-10-06
3642 Ethylenediaminetetraacetic acid promotes the accumulation of nitric oxide
Zhang, S.; Liu, S.; Xiao, S.; Li, M.; Huang, J.; Yan, K.; Yang, G.; Zheng, C.; Wu, C.
10.1101/2020.10.05.326413 — molecular biology — Posted on 2020-10-06
3643 Archaeal SepF is essential for cell division in Haloferax volcanii
Nussbaum, P.; Gerstner, M. K.; Dingethal, M.; Erb, C.; Albers, S.-V.
10.1101/2020.10.06.327809 — microbiology — Posted on 2020-10-06
3644 Experimental Reptarenavirus Infection of Boa constrictor and Python regius
Hetzel, U.; Korzyukov, Y.; Keller, S.; Szirovicza, L.; Pesch, T.; Vapalahti, O.; Kipar, A.; Hepojoki, J.
10.1101/2020.10.05.327502 — microbiology — Posted on 2020-10-06
3645 Airway bacterial and fungal microbiome in chronic obstructive pulmonary disease
Liu, H.; Liang, Z.; Cao, N.; Tan, X.-l.; Liu, Z.; Wang, F.; Yang, Y.; Li, C.; He, Y.; Su, J.; Chen, R.; Wang, Z.; Zhou, H.-W.
10.1101/2020.10.05.327536 — microbiology — Posted on 2020-10-06
3647 SepF is the FtsZ-anchor in Archaea: implications for cell division in the Last Universal Common Ancestor
Pende, N.; Sogues, A.; Megrian, D.; Palabikyan, H.; Sartori-Rupp, A.; Graña, M.; Rittmann, S. K.- M. R.; Wehenkel, A. M.; Alzari, P.; Gribaldo, S.
10.1101/2020.10.06.328377 — microbiology — Posted on 2020-10-06
3648 Protoplast fusion in Bacillus species produces frequent, unbiased, genome-wide homologous recombination
Burdick, L.; Streich, J.; Vasileva, D.; Klingeman, D. M.; Chhetri, H.; Ellis, J.; Close, D.; Jacobson, D.; Michener, J. K.
10.1101/2020.10.06.328625 — microbiology — Posted on 2020-10-06
3650 Time-dependent modulation of gut microbiome in response to systemic antifungal agents
Udawatte, N. S.; Wook, K. S.; Wang, Y.; Manzanero, S.; Arumugam, T. V.; Seneviratne, C. J.
10.1101/2020.10.05.315184 — microbiology — Posted on 2020-10-06
3651 Development of a three-compartment in vitro simulator of the Atlantic Salmon GI tract and associated microbial communities: SalmoSim
Kazlauskaite, R.; Cheaib, B.; Heys, C.; Ijaz, U. Z.; Connelly, S.; Sloan, W. T.; Russell, J.; Martinez-Rubio, L.; Sweetman, J.; Kitts, A.; McGinnity, P.; Lyons, P.; Llewellyn, M.
10.1101/2020.10.06.327858 — microbiology — Posted on 2020-10-06
3652 Multi-Clonal Live SARS-CoV-2 In Vitro Neutralization by Antibodies Isolated from Severe COVID-19 Convalescent Donors
Mor, M.; Werbner, M.; Alter, J.; Safra, M.; Chomsky, E.; Hada-Neeman, S.; Polonsky, K.; Nowell, C.; Clark, A.; Roitburd-Berman, A.; Ben-Shalom, N.; Navon, M.; Rafael, D.; Sharim, H.; Kiner, E.; Griffis, E.; Gershoni, J. M.; Kobiler, O.; Leibel, S. L.; Zimhony, O.; Carlin, A. F.; Yaari, G.; Dassau, M.; Gal-Tanamy, M.; Hagin, D.; Croker, B. A.; Freund, N.
10.1101/2020.10.06.323634 — immunology — Posted on 2020-10-06
3653 Cortical Organoids Model Early Brain Development Disrupted by 16p11.2 Copy Number Variants in Autism
Urresti, J.; Zhang, P.; Moran-Losada, P.; Yu, N.-K.; Negraes, P. D.; Trujillo, C. A.; Antaki, D.; Amar, M.; Chau, K.; Pramod, A. B.; Diedrich, J.; Tejwani, L.; Romero, S.; Sebat, J.; Yates, J. R.; Muotri, A. R.; Iakoucheva, L. M.
10.1101/2020.06.25.172262 — neuroscience — Posted on 2020-10-06
3654 Superior Colliculus-Projecting GABAergic Retinal Ganglion Cells Mediate Looming-Evoked Flight Response
Luo, X.; Cai, D.; Shen, K.; Deng, Q.; Lei, X.; Jin, S.; Zeng, W.-B.; Li, H.; Xu, F.; Huang, L.; Ren, C.; Luo, M.-H.; Xie, T.; Shen, Y.
10.1101/2020.05.14.090167 — neuroscience — Posted on 2020-10-06
3655 Brain Angiopathy and Impaired Glucose Metabolism in Model Mice with Psychiatric-Related Phenotypes
Hirai, S.; Miwa, H.; Tanaka, T.; Toriumi, K.; Kunii, Y.; Sakamoto, T.; Hino, M.; Izumi, R.; Nagaoka, A.; Yabe, H.; Nakamachi, T.; Shioda, S.; Dan, T.; Miyata, T.; Nishito, Y.; Shimbo, H.; Suzuki, K.; Miyashita, M.; Itokawa, M.; Arai, M.; Okado, H.
10.1101/2020.02.14.939546 — neuroscience — Posted on 2020-10-06
3659 GNS561 exhibits potent in vitro antiviral activity against SARS-CoV-2 through autophagy inhibition
Halfon, P.; Bestion, E.; Zandi, K.; Andreani, J.; Baudoin, J.-P.; LA SCOLA, B.; Mege, J.-L.; Mezouar, S.; Schinazi, R. F.
10.1101/2020.10.06.327635 — pathology — Posted on 2020-10-06
3660 Helicobacter pylori accelerates KRAS-dependent gastric dysplasia
O'Brien, V. P.; Koehne, A.; Dubrulle, J.; Rodriguez, A.; Leverich, C.; Kong, P.; Campbell, J.; Pierce, R.; Goldenring, J.; Choi, E.; Salama, N.
10.1101/2020.10.06.328518 — cancer biology — Posted on 2020-10-06
3662 Single depolymerizing and transport kinesins stabilize microtubule ends
Ciorita, A.; Bugiel, M.; Sudhakar, S.; Schaeffer, E.; Jannasch, A.
10.1101/2020.10.05.326330 — biophysics — Posted on 2020-10-06
3665 Subcutaneous nanotherapy repurposes the immunosuppressive mechanism of rapamycin to enhance allogeneic islet graft viability
Burke, J.; Zhang, X.; Bobbala, S.; Frey, M.; Fuentes, C.; Haddad, H.; Allen, S.; Richardson, R.; Ameer, G.; Scott, E. A.
10.1101/2020.09.03.281923 — bioengineering — Posted on 2020-10-06
3667 Benchmarking non-targeted metabolomics using yeast derived libraries
Rampler, E.; Hermann, G.; Grabmann, G.; Abiead, Y. E.; Schoeny, H.; Baumgartinger, C.; Koecher, T.; Koellensperger, G.
10.1101/2020.10.06.319160 — biochemistry — Posted on 2020-10-06
3670 Polygenic prediction of school performance in children with and without psychiatric disorders
Rajagopal, V. M.; Trabjerg, B. B.; Grove, J.; Horsdal, H. T.; Petersen, L. V.; Bulik, C.; Bybjerg-Grauholm, J.; Baekvad-Hansen, M.; Hougaard, D. M.; Mors, O.; Nordentoft, M.; Werge, T.; Mortensen, P. B.; Agerbo, E.; Borglum, A. D.; Demontis, D.
10.1101/2020.07.15.203661 — genetics — Posted on 2020-10-06
3676 The smORF-containing gene mille-pattes is required for moulting and Trypanosoma cruzi metacyclogenesis in the Chagas disease vector Rhodnius prolixus
Azevedo, C.; Rodrigues, B.; Alves, S.; Ribeiro, L.; Logullo, C.; Nepomuceno, J.; Roberto-Silva, J.; Mury, F.; Nunes-da-Fonseca, R.
10.1101/2020.10.06.324897 — molecular biology — Posted on 2020-10-06
3677 Systematic discovery and functional interrogation of SARS-CoV-2 viral RNA-host protein interactions during infection
Flynn, R. A.; Belk, J. A.; Qi, Y.; Yasumoto, Y.; Schmitz, C. O.; Mumbach, M. R.; Limaye, A.; Wei, J.; Alfajaro, M. M.; Parker, K. R.; Chang, H. Y.; Horvath, T. L.; Carette, J. E.; Bertozzi, C.; Wilen, C. B.; Satpathy, A. T.
10.1101/2020.10.06.327445 — microbiology — Posted on 2020-10-06
3679 RegTools: Integrated analysis of genomic and transcriptomic data for the discovery of splicing variants in cancer
Cotto, K. C.; Feng, Y.-Y.; Ramu, A.; Skidmore, Z. L.; Kunisaki, J.; Richters, M.; Freshour, S.; Lin, Y.; Chapman, W.; Uppaulri, R.; Govindan, R.; Griffith, O. L.; Griffith, M.
10.1101/436634 — bioinformatics — Posted on 2020-10-06
3681 Model-based inference of neutralizing antibody avidities against influenza virus
Linnik, J.; Syedbasha, M.; Hollenstein, Y.; Halter, J.; Egli, A.; Stelling, J.
10.1101/2020.10.05.326215 — immunology — Posted on 2020-10-06
3686 Coronavirus infection and PARP expression dysregulate the NAD Metabolome: an actionable component of innate immunity
Heer, C. D.; Sanderson, D. J.; Voth, L. S.; Alhammad, Y. M. O.; Schmidt, M. S.; Trammell, S. A. J.; Perlman, S.; Cohen, M. S.; Fehr, A. R.; Brenner, C.
10.1101/2020.04.17.047480 — microbiology — Posted on 2020-10-06
3687 Design of a highly thermotolerant, immunogenic SARS-CoV-2 spike fragment
Malladi, S. K.; Singh, R.; Pandey, S.; Gayathri, S.; Kanjo, K.; Ahmed, S.; Khan, M. S.; Kalita, P.; Girish, N.; Upadhyaya, A.; Reddy, P.; Pramanick, I.; Bhasin, M.; Mani, S.; Bhattacharyya, S.; Joseph, J.; Thankamani, K.; Raj, V. S.; Dutta, S.; Singh, R.; Nadig, G.; Varadarajan, R.
10.1101/2020.08.15.252437 — biophysics — Posted on 2020-10-06
3689 Divergent sensory processing converges in frontal cortex for a planned motor response
Esmaeili, V.; Tamura, K.; Muscinelli, S. P.; Modirshanechi, A.; Boscaglia, M.; Lee, A. B.; Oryshchuk, A.; Foustoukos, G.; Liu, Y.; Crochet, S.; Gerstner, W.; Petersen, C. C. H.
10.1101/2020.10.06.326678 — neuroscience — Posted on 2020-10-06
3690 Extensive Intratumor Proteogenomic Heterogeneity Revealed by Multiregion Sampling in High-Grade Serous Ovarian Tumor Specimens
Hunt, A. L.; Bateman, N. W.; Barakat, W.; Makohon-Moore, S.; Hood, B. L.; Conrads, K. A.; Zhou, M.; Calvert, V.; Pierobon, M.; Loffredo, J.; Litzi, T. J.; Oliver, J.; Mitchell, D.; Gist, G.; Rojas, C.; Blanton, B.; Robinson, E. L.; Odunsi, K.; Sood, A. K.; Casablanca, Y.; Shriver, C. D.; Darcy, K. M.; Petricoin, E. F.; Rao, U. N.; Maxwell, G. L.; Conrads, T. P.
10.1101/761155 — cancer biology — Posted on 2020-10-06
3693 Bayesian segmentation of spatially resolved transcriptomics data
Petukhov, V.; Khodosevich, K.; Soldatov, R. A.; Kharchenko, P. V.
10.1101/2020.10.05.326777 — bioinformatics — Posted on 2020-10-06
3694 LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection
Jones, B. E.; Brown-Augsburger, P. L.; Corbett, K. S.; Westendorf, K.; Davies, J.; Cujec, T. P.; Wiethoff, C. M.; Blackbourne, J. L.; Heinz, B. A.; Foster, D.; Higgs, R. E.; Balasubramaniam, D.; Wang, L.; Bidshahri, R.; Kraft, L.; Hwang, Y.; Zentelis, S.; Jepson, K. R.; Goya, R.; Smith, M. A.; Collins, D. W.; Hinshaw, S. J.; Tycho, S. A.; Pellacani, D.; Xiang, P.; Muthuraman, K.; Sobhanifar, S.; Piper, M. H.; Triana, F. J.; Hendle, J.; Pustilnik, A.; Adams, A. C.; Berens, S. J.; Baric, R. S.; Martinez, D. R.; Cross, R. W.; Geisbert, T. W.; Borisevich, V.; Abiona, O.; Belli, H. M.; de Vries, M.
10.1101/2020.09.30.318972 — immunology — Posted on 2020-10-06
3696 Evaluating CRISPR-based Prime Editing for cancer modeling and CFTR repair in intestinal organoids
Geurts, M. H.; de Poel, E.; Pleguezuelos-Manzano, C.; Carrillo, L.; Andersson-Rolf, A.; Boretto, M. G.; Beekman, J.; Clevers, H. C.
10.1101/2020.10.05.325837 — genetics — Posted on 2020-10-06
3697 Metformin alleviates aging-associated cellular senescence of human adipose stem cells and derived adipocytes
Mantecon, M.; Le Pelletier, L.; Gorwood, J.; Auclair, M.; Atlan, M.; Feve, B.; Capeau, J.; Lagathu, C.; Bereziat, V.
10.1101/2020.10.05.326546 — cell biology — Posted on 2020-10-06
3699 Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration
Begley, V.; Jordan-Pla, A.; Penate, X.; Garrido-Godino, A. I.; Challal, D.; Cuevas-Bermudez, A.; Mitjavila, A.; Barucco, M.; Gutierrez, G.; Singh, A.; Alepuz, P.; Navarro, F.; Libri, D.; Perez-Ortin, J. E.; Chavez, S.
10.1101/2020.06.02.129171 — genomics — Posted on 2020-10-06
3703 Ranking microbial metabolomic and genomic links in the NPLinker framework using complementary scoring functions
Hjorleifsson Eldjarn, G.; Ramsey, A.; van der Hooft, J. J. J.; Duncan, K. R.; Soldatou, S.; Rousu, J.; Daly, R.; Wandy, J.; Rogers, S.
10.1101/2020.06.12.148205 — systems biology — Posted on 2020-10-06
3705 Multimodal 3D atlas of the macaque monkey motor and premotor cortex
Rapan, L.; Froudist-Walsh, S.; Niu, M.; Xu, T.; Funck, T.; Zilles, K.; Palomero-Gallagher, N.
10.1101/2020.10.05.326579 — neuroscience — Posted on 2020-10-06
3708 Putamen volume predicts real-time fMRI neurofeedback learning success across paradigms and neurofeedback target regions
Zhao, Z.; Yao, S.; Zweerings, J.; Zhou, X.; Zhou, F.; Chen, H.; Kendrick, K. M.; Mathiak, K.; Becker, B.
10.1101/2020.10.05.327262 — neuroscience — Posted on 2020-10-06
3719 Chromosomes distribute randomly to, but not within, human neutrophil nuclear lobes
Keenan, C. R.; Mlodzianoski, M. J.; Coughlan, H. D.; Bediaga, N. G.; Naselli, G.; Lucas, E. C.; Wang, Q.; de Graaf, C. A.; Hilton, D. J.; Harrison, L. C.; Smyth, G. K.; Rogers, K. L.; Boudier, T.; Allan, R. S.; Johanson, T. M.
10.1101/2020.10.05.326009 — immunology — Posted on 2020-10-05
3721 Genetic Variance for Fusarium Crown Rot Tolerance in Durum Wheat
Kadkol, G. P.; Meza, J.; Simpfendorfer, S.; Harden, S.; Cullis, B.
10.1101/2020.10.05.326058 — plant biology — Posted on 2020-10-05
3722 Metabolomic profiling identifies complex lipid species associated with response to weight loss interventions
Bihlmeyer, N. A.; Kwee, L. C.; Clish, C. B.; Deik, A. A.; Gerszten, R. E.; Pagidipati, N. J.; Laferrere, B.; Svetkey, L. P.; Newgard, C. B.; Kraus, W. E.; Shah, S. H.
10.1101/2020.10.05.326025 — physiology — Posted on 2020-10-05
3726 Nano-particles carried by multiple dynein motors: A Self-Regulating Nano-Machine
Fayer, I.; Halbi, G.; Aranovich, D.; Gat, S.; Bar, S.; Erukhimovitch, V.; Granek, R.; Bernheim, A.
10.1101/2020.07.09.194720 — biophysics — Posted on 2020-10-05
3728 Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model
Shibata, T.; Nagano, K.; Ueyama, M.; Ninomiya, K.; Tetsuro, H.; Nagai, Y.; Ishikawa, K.; Kawai, G.; Nakatani, K.
10.1101/2020.10.05.323261 — biochemistry — Posted on 2020-10-05
3729 Genetic Adaptation in New York City Rats
Harpak, A.; Garud, N.; Rosenberg, N. A.; Petrov, D. A.; Combs, M.; Pennings, P. S.; Munshi-South, J.
10.1101/2020.02.07.938969 — evolutionary biology — Posted on 2020-10-05
3730 Evolutionary history of Carnivora (Mammalia, Laurasiatheria) inferred from mitochondrial genomes
Hassanin, A.; Veron, G.; Ropiquet, A.; Jansen van Vuuren, B.; Lecu, A.; Goodman, S.; Haider, J.; Nguyen, T. T.
10.1101/2020.10.05.326090 — evolutionary biology — Posted on 2020-10-05
3733 Regional Differences in the Ghrelin-Growth Hormone Secretagogue Receptor Signalling System in Human Heart Disease
Sullivan, R.; Randhawa, V.; Lalonde, T.; Yu, T.; Kiaii, B.; Luyt, L.; Wisenberg, G.; Dhanvantari, S.
10.1101/2020.07.13.201319 — molecular biology — Posted on 2020-10-05
3734 Glycine acylation and trafficking of a new class of bacterial lipoprotein by a composite secretion system
Icke, C.; Hodges, F.; Pullela, K.; McKeand, S.; Bryant, J. A.; Cunningham, A. F.; Cole, J. A.; Henderson, I. R.
10.1101/2020.09.23.310854 — microbiology — Posted on 2020-10-05
3736 Music-selective neural populations arise without musical training
Boebinger, D. L.; Norman-Haignere, S. V.; McDermott, J. H.; Kanwisher, N.
10.1101/2020.01.10.902189 — neuroscience — Posted on 2020-10-05
3737 PapRIV, a BV-2 microglial cell activating quorum sensing peptide
Janssens, Y.; Debunne, N.; De Spiegeleer, A.; Wynendaele, E.; Planas, M.; Feliu, L.; Quarta, A.; Claes, C.; Van Dam, D.; De Deyn, P. P.; Ponsaerts, P.; Blurton-Jones, M.; De Spiegeleer, B.
10.1101/2020.10.05.327148 — neuroscience — Posted on 2020-10-05
3738 Arabidopsis inositol polyphosphate kinases regulate COP9 signalosome functions in phosphate-homeostasis
Walia, Y.; Ingole, K. D.; Kasera, M.; Peddiraju, S.; Laha, D.; Schaaf, G.; BHATTACHARJEE, S.
10.1101/2020.10.02.323584 — plant biology — Posted on 2020-10-05
3741 Precision targeting of the Plasminogen Activator Inhibitor-1 mechanism increases efficacy of fibrinolytic therapy in empyema.
Florova, G.; Girard, R. A.; Azghani, A. O.; Sarva, K.; Buchanan, A.; Karandashova, S.; DeVera, C. J.; Hill, D.; Chamiso, M.; Koenig, K.; Cines, D. B.; Idell, S.; Komissarov, A. A.
10.1101/2020.10.05.325688 — biochemistry — Posted on 2020-10-05
3744 Enhancing biological signals and detection rates in single-cell RNA-seq experiments with cDNA library equalization
Bacher, R.; Chu, L.-F.; Argus, C.; Bolin, J. M.; Knight, P.; Thomson, J. A.; Stewart, R.; Kendziorski, C.
10.1101/2020.10.05.326553 — genomics — Posted on 2020-10-05
3745 Functional interpretation of ATAD3A variants in neuro-mitochondrial phenotypes
Yap, Z. Y.; Park, Y.; Wortmann, S. B.; Gunning, A. C.; Lee, S.; Duraine, L.; Wilichowski, E.; Wilson, K.; Mayr, J. A.; Wagner, M.; Li, H.; Kini, U.; Black, E. D.; Lupski, J. R.; Ellard, S.; Westphal, D. S.; Harel, T.; Yoon, W. H.
10.1101/2020.10.05.318519 — genetics — Posted on 2020-10-05
3747 Cargo-specific recruitment in clathrin and dynamin-independent endocytosis
Moreno-Layseca, P.; Jäntti, N. Z.; Godbole, R.; Sommer, C.; Jacquemet, G.; Al-Akhrass, H.; Kronqvist, P.; Kallionpaa, R. E.; Oliveira-Ferrer, L.; Cervero, P.; Linder, S.; Aepfelbacher, M.; Rae, J.; Parton, R. G.; Disanza, A.; Scita, G.; Mayor, S.; Selbach, M.; Veltel, S.; Ivaska, J.
10.1101/2020.10.05.323295 — cell biology — Posted on 2020-10-05
3749 CRISPR/Cas9-engineered inducible gametocyte producer lines as a novel tool for basic and applied research on Plasmodium falciparum malaria transmission stages
Boltryk, S. D.; Passecker, A.; Alder, A.; van de Vegte-Bolmer, M.; Sauerwein, R. W.; Brancucci, N. M. B.; Beck, H.-P.; Gilberger, T.-W.; Voss, T. S.
10.1101/2020.10.05.326868 — microbiology — Posted on 2020-10-05
3751 Hepatic FGF21 mediates tissue tolerance during bacterial inflammation by preserving cardiac function
Huen, S. C.; Wang, A.; Feola, K.; Desrouleaux, R.; Luan, H. H.; Hogg, R.; Zhang, C.; Zhang, Q.-J.; Liu, Z.-P.; Medzhitov, R.
10.1101/2020.10.05.310508 — immunology — Posted on 2020-10-05
3755 Role of 5-HT2C receptors in zebrafish alarm reactions and post-exposure behavior
do Carmo Silva, R. X.; do Nascimento, B. G.; Gomes, G. C. V.; Holanda da Silva, N. A.; Pinheiro, J. S.; da Silva Chaves, S. N.; Pimentel, A. F. N.; Costa, B. P. D.; Herculano, A. M.; Lima-Maximino, M.; Maximino, C.
10.1101/2020.10.04.324202 — neuroscience — Posted on 2020-10-05
3756 The lncRNA MARS modulates the epigenetic reprogramming of the marneral cluster in response to ABA
Roule, T.; Ariel, F.; Hartmann, C.; Gutierrez-Marcos, J.; Hussain, N.; Crespi, M.; Blein, T.
10.1101/2020.08.10.236562 — plant biology — Posted on 2020-10-05
3758 Hormonal regulation of Semaphorin 7a in ER+ breast cancer drives therapeutic resistance
Crump, L. S.; Wyatt, G. L.; Rutherford, T. R.; Richer, J. K.; Porter, W. W.; Lyons, T. R.
10.1101/650135 — cancer biology — Posted on 2020-10-05
3759 Single depolymerizing and transport kinesins stabilize microtubule ends
Ciorita, A.; Bugiel, M.; Sudhakar, S.; Schaeffer, E.; Jannasch, A.
10.1101/2020.10.05.326330 — biophysics — Posted on 2020-10-05
3761 Genome analysis of Salmonella enterica serovar Typhimurium bacteriophage L, indicator for StySA (StyLT2III) restriction-modification system action
Zaworski, J.; McClung, C.; Ruse, C.; Weigele, P. R.; Hendrix, R. W.; Ko, C.-C.; Edgar, R.; Hatfull, G.; Casjens, S.; Raleigh, E. A.
10.1101/2020.10.05.325894 — genetics — Posted on 2020-10-05
3762 Immune Fingerprinting through Repertoire Similarity
Dupic, T.; Bensouda Koraichi, M.; Minervina, A.; Pogorelyy, M.; Mora, T.; Walczak, A. M.
10.1101/2020.06.24.168484 — genetics — Posted on 2020-10-05
3764 Multiplexing Mutation Rate Assessment: Determining Pathogenicity of Msh2 Variants in S. cerevisiae
Ollodart, A. R.; Yeh, C.-L. C.; Miller, A. W.; Shirts, B. H.; Gordon, A. S.; Dunham, M. J.
10.1101/2020.10.05.325902 — genetics — Posted on 2020-10-05
3767 Coding variants identified in diabetic patients alter PICK1 BAR domain function in insulin granule biogenesis
Andersen, R. C.; Lycas, M. D.; Schmidt, J. H.; Christensen, N. R.; Lund, V. K.; Rombach, J.; Stoklund, M.; Stapleton, D.; Noes-Holt, G.; Keller, M. P.; Jansen, A. M.; Herlo, R.; Kjaerulff, O.; Holst, B.; Attie, A. D.; Gether, U.; Madsen, k. L.
10.1101/2020.10.05.325951 — cell biology — Posted on 2020-10-05
3769 Phospho-regulated auto-inhibition of Cnn controls microtubule nucleation during cell division
Tovey, C. A.; Tsuji, C.; Egerton, A.; Bernard, F.; Guichet, A.; de la Roche, M. A.; Conduit, P. T.
10.1101/2020.10.05.326587 — cell biology — Posted on 2020-10-05
3770 SMARCAD1 Mediated Active Replication Fork Stability Maintains Genome Integrity
Lo, C.; van Toorn, M.; Gaggioli, V.; Paes Dias, M.; Zhu, Y.; Maria Manolika, E.; Zhao, W.; van der Does, M.; Mukherjee, C.; Souto Goncalves, J.; van Royen, M.; French, P.; Demmers, J.; Smal, I.; Lans, H.; Wheeler, D.; Jonkers, J.; Ray Chaudhuri, A.; Marteijn, J.; Taneja, N.
10.1101/2020.10.05.326223 — cell biology — Posted on 2020-10-05
3772 Obtaining deeper insights into microbiome diversity using a simple method to block host and non-targets in amplicon sequencing
Mayer, T.; Mari, A.; Almario, J.; Murillo-Roos, M.; Abdullah, M.; Dombrowski, N.; Hacquard, S.; Kemen, E. M.; Agler, M. T.
10.1101/2020.10.05.322305 — microbiology — Posted on 2020-10-05
3774 Model-based inference of neutralizing antibody avidities against influenza virus
Linnik, J.; Syedbasha, M.; Hollenstein, Y.; Halter, J.; Egli, A.; Stelling, J.
10.1101/2020.10.05.326215 — immunology — Posted on 2020-10-05
3775 Targeting transcriptional coregulator OCA-B/Pou2af1 blocks activated autoreactive T cells in the pancreas and type-1 diabetes
Kim, H.; Perovanovic, J.; Shakya, A.; Shen, Z.; German, C. N.; Ibarra, A.; Jafek, J. L.; Lin, N.-P.; Evavold, B. D.; Chou, D. H.- C.; Jensen, P. E.; He, X.; Tantin, D.
10.1101/2020.02.06.937839 — immunology — Posted on 2020-10-05
3782 Harnessing machine learning to unravel protein degradation in Escherichia coli
Pupko, T.; Nagar, N.; Ecker, N.; Loewenthal, G.; Avram, O.; Ben-Meir, D.; Biran, D.; Ron, E.
10.1101/2020.10.04.325795 — microbiology — Posted on 2020-10-05
3783 Composition and stage dynamics of mitochondrial complexes in Plasmodium falciparum
Evers, F.; Cabrera-Orefice, A.; Elurbe, D. M.; Kea-te Lindert, M.; Boltryk, S. D.; Voss, T. S.; Huynen, M.; Brandt, U.; Kooij, T. W. A.
10.1101/2020.10.05.326496 — microbiology — Posted on 2020-10-05
3784 Novel inhibitors of E. coli lipoprotein diacylglyceryl transferase are insensitive to resistance caused by lpp deletion
Diao, J.; Komura, R.; Sano, T.; Pantua, H.; Storek, K. M.; Inaba, H.; Ogawa, H.; Noland, C. L.; Peng, Y.; Gloor, S. L.; Yan, D.; Kang, J.; Katakam, A. K.; Nickerson, N. N.; Austin, C. D.; Murray, J.; Rutherford, S. T.; Reichelt, M.; Xu, Y.; Xu, M.; Yanagida, H.; Nishikawa, J.; Reid, P. C.; Cunningham, C.; Kapadia, S. B.
10.1101/2020.10.04.325589 — microbiology — Posted on 2020-10-05
3786 Evidence and urgency-related EEG signals during dynamic decision-making in humans
Yau, Y.; Hinault, T. T.; Taylor, M.; Cisek, P.; Fellows, L. K.; Dagher, A.
10.1101/2020.10.02.323683 — neuroscience — Posted on 2020-10-05
3787 Environmental flexibility does not explain metabolic robustness
Libiseller-Egger, J.; Coltman, B.; Gerstl, M. P.; Zanghellini, J.
10.1101/2020.10.04.325407 — systems biology — Posted on 2020-10-05
3789 RESCRIPt: Reproducible sequence taxonomy reference database management for the masses
Robeson, M. S.; O'Rourke, D. R.; Kaehler, B. D.; Ziemski, M.; Dillon, M. R.; Foster, J. T.; Bokulich, N. A.
10.1101/2020.10.05.326504 — bioinformatics — Posted on 2020-10-05
3790 CancerMIRNome: a web server for interactive analysis and visualization of cancer miRNome data
Li, R.; Qu, H.; Wang, S.; Wang, X.; Cui, Y.; Yu, L.; Chater, J. M.; Zhou, R.; Jia, Q.; Traband, R.; Yuan, D.; Zhu, J.; Zhong, W.-D.; Jia, Z.
10.1101/2020.10.04.325670 — bioinformatics — Posted on 2020-10-05
3791 NAP-CNB: Bioinformatic pipeline to predict MHC-I-restricted T cell epitopes in mice
Wert-Carvajal, C.; Sanchez-Garcia, R.; Macias, J. R.; Sanz-Pamplona, R.; Mendez Perez, A.; Alemany, R.; Veiga Chacon, E.; Sorzano, C. O. S.; Munoz-Barrutia, A.
10.1101/2020.10.05.327015 — bioinformatics — Posted on 2020-10-05
3793 β-Amyloid peptides tailor switching behaviors of Donor-Acceptor Stenhouse Adducts
Zheng, C.; Yu, Y.; Kuang, S.; Zhu, B.; Zhou, H.; zhang, s.-q.; Yang, J.; Shi, L.; Ran, C.
10.1101/2020.10.04.325696 — biochemistry — Posted on 2020-10-05
3794 Hsf1 is SUMOylated in the activated trimeric state
Kmiecik, S. W.; Drzewicka, K.; Melchior, F.; Mayer, M. P.
10.1101/2020.10.05.327064 — biochemistry — Posted on 2020-10-05
3796 High-throughput phenotypic characterization of zebrafish CRISPR mutants of DNA repair genes
Shin, U.; Nakhro, K.; Oh, C.-K.; Carrington, B.; Song, H.; Varshney, G. K.; Kim, Y.; Song, H.; Jeon, S.; Robbins, G.; Kim, S.; Yoon, S.; Choi, Y.; Park, S.; Kim, Y. J.; Burgess, S. M.; Kang, S.; Sood, R.; Lee, Y.; Myung, K.
10.1101/2020.10.04.325621 — developmental biology — Posted on 2020-10-05
3797 DOT1L methyltransferase regulates the calcium influx in erythroid progenitor cells in response to erythropoietin
Feng, Y.; Borosha, S.; Ratri, A.; Housami, S. M.; Chakravarthi, V. P.; Wang, H.; Vivian, J. L.; Fields, T. A.; Kinsey, W. H.; Rumi, M. A.; Fields, P. E.
10.1101/2020.10.04.325746 — developmental biology — Posted on 2020-10-05
3799 A novel juxtamembrane basolateral targeting motif regulates TGF-β receptor signaling in Drosophila
Peterson, A. J.; Murphy, S. J.; Mundt, M. G.; Shimell, M.; Leof, E. B.; O'Connor, M. B.
10.1101/2020.10.05.327056 — cell biology — Posted on 2020-10-05
3801 Phenomenon of music-induced opening of the blood-brain barrier in healthy mice
Semyachkina-Glushkovskaya, O. V.; Sharif Esmat, E.; Bragin, D.; Bragina, O.; Shirokov, A.; Navolokin, N.; Yirong, Y.; Abdurashitov, A.; Khorovodov, A.; Terskov, A.; Klimova, M.; Mamedova, A.; Fedosov, I.; Tuchin, V.; Kurths, J.
10.1101/2020.10.03.324699 — neuroscience — Posted on 2020-10-05
3808 Exploring heteroaromatic rings as a replacement for the labile amide of antiplasmodial pantothenamides
Guan, J.; Spry, C.; Tjhin, E.; Yang, P.; Kittikool, T.; Howieson, V.; Ling, H.; Starrs, L.; Burgio, G.; Saliba, K. J.; Auclair, K.
10.1101/2020.10.02.324079 — pharmacology and toxicology — Posted on 2020-10-05
3812 Automatic Recognition of Auditory Brainstem Response Characteristic Waveform based on BiLSTM
Chen, C.; Zhan, L.; Pan, X.; Wang, Z.; Guo, X.; Qin, H.; Xiong, F.; Shi, W.; Shi, M.; Ji, F.; Wang, Q.; Yu, N.; Xiao, R.
10.1101/2020.10.03.324665 — bioinformatics — Posted on 2020-10-05
3814 New targets acquired: improving locus recovery from the Angiosperms353 probe set
McLay, T. G.; Gunn, B. F.; Ning, W.; Tate, J. A.; Nauheimer, L.; Joyce, E. M.; Simpson, L.; Schmidt-Lebuhn, A. N.; Baker, W. J.; Forest, F.; Jackson, C. J.
10.1101/2020.10.04.325571 — bioinformatics — Posted on 2020-10-05
3816 Reconstructing the diet, trophic level, and migration pattern of Mysticete whales based on baleen isotopic composition.
Riekenberg, P. M.; Camalich, J.; Svensson, E.; IJsseldijk, L. L.; Brasseur, S. M. J. M.; Witbaard, R.; Leopold, M. F.; Rebolledo, E. B.; Middelburg, J. J.; van der Meer, M.; Sinninghe Damste, J. S.; Schouten, S.
10.1101/2020.10.04.301341 — ecology — Posted on 2020-10-05
3817 Biogeographical and ecological factors associated with kill rates of an apex predator
Cristescu, B.; Elbroch, L. M.; Dellinger, J. A.; Binder, W.; Wilmers, C. C.; Wittmer, H. U.
10.1101/2020.10.04.325779 — ecology — Posted on 2020-10-05
3818 EslB is required for cell wall biosynthesis and modification in Listeria monocytogenes
Rismondo, J.; Schulz, L. M.; Yacoub, M.; Wadhawan, A.; Hoppert, M.; Dionne, M. S.; Gründling, A.
10.1101/2020.02.03.932061 — microbiology — Posted on 2020-10-05
3822 Neuroinflammation characterizes the earliest changes in Alzheimer's disease pathology and associated subjective cognitive impairment in adult hydrocephalus biopsies
Huang, W.; Bartosch, A. M.; Xiao, H.; Flowers, X.; Leskinen, S.; Tomljanovic, Z.; Iodice, G.; Boyett, D.; Spinazzi, E.; Menon, V.; McGovern, R. A.; McKhann, G. M.; Teich, A. F.
10.1101/2020.10.01.322511 — neuroscience — Posted on 2020-10-05
3824 How motivational signals disrupt metacognitive signals in the human VMPFC.
Hoven, M.; Brunner, G.; de Boer, N. S.; Goudriaan, A. E.; Denys, D.; van Holst, R. J.; Luigjes, J.; Lebreton, M.
10.1101/2020.10.02.323550 — neuroscience — Posted on 2020-10-05
3825 In vitro efficacy of Artemisinin-based treatments against SARS-CoV-2
Gilmore, K.; Zhou, Y.; Ramirez, S.; Pham, L. V.; Fahnoe, U.; Feng, S.; Offersgaard, A.; Trimpert, J.; Bukh, J.; Osterrieder, K.; Gottwein, J.; Seeberger, P. H.
10.1101/2020.10.05.326637 — pharmacology and toxicology — Posted on 2020-10-05
3827 Proteolytic activation of the SARS-CoV-2 spike S1/S2 site: a re-evaluation of furin cleavage
Tang, T.; Jaimes, J. A.; Bidon, M. K.; Straus, M. R.; Daniel, S.; Whittaker, G. R.
10.1101/2020.10.04.325522 — microbiology — Posted on 2020-10-05
3828 Comprehensive characterization of migration profiles of murine cerebral cortical neurons during development using FlashTag labeling
Yoshinaga, S.; Shin, M.; Kitazawa, A.; Ishii, K.; Tanuma, M.; Kasai, A.; Hashimoto, H.; Kubo, K.-i.; Nakajima, K.
10.1101/2020.10.05.317925 — neuroscience — Posted on 2020-10-05
3830 Evolution of molecular determinants for SUMO-activating enzyme subcellular localization in plants
Mas, A.; Castano-Miquel, L.; Carretero-Paulet, L.; Colome, N.; Canals, F.; Lois, L. M.
10.1101/2020.10.05.326249 — biochemistry — Posted on 2020-10-05
3831 The contribution of PARP1, PARP2 and poly(ADP-ribosyl)ation to base excision repair in the nucleosomal context
Kutuzov, M.; Belousova, E.; Kurgina, T.; Ukraintsev, A.; Vasil'eva, I.; Khodyreva, S.; Lavrik, O.
10.1101/2020.10.05.325944 — biochemistry — Posted on 2020-10-05
3832 TopBP1 assembles nuclear condensates to switch on ATR signalling.
Frattini, C.; Promonet, A.; Alghoul, E.; Vidal Eychenie, S.; Lamarque, M.; Blanchard, M.-P.; Urbach, S.; Basbous, J.; Constantinou, A.
10.1101/2020.10.05.326181 — cell biology — Posted on 2020-10-05
3833 CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels
Gonçalves, A. B.; Joensen, B. B.; Hasselbalch, S. K.; Martens, P.; Ohlsen, S. K.; Quinodoz, M.; Nikopoulus, K.; Jeppesen, M. P. D.; Weiss, C.; Christensen, S. T.; Patzke, S.; Rivolta, C.; Andersen, J. S.; Farinelli, P.; Pedersen, L. B.
10.1101/2020.10.05.325936 — cell biology — Posted on 2020-10-05
3835 Genome wide analysis of gene dosage in 24,092 individuals shows that 10,000 genes modulate cognitive ability
Huguet, G.; Schramm, C.; Douard, E. A.; Tamer, P.; Main, A.; Monin, P.; England, J.; Jizi, K.; Renne, T.; Poirier, M.; Nowak, S.; Martin, C.-O.; Younis, N.; Knoth, I. S.; Jean Louis, M.; Saci, Z.; Auger, M.; Tihy, F.; Mathonnet, G.; Maftei, C.; Leveille, F.; Porteous, D.; Davies, G.; Redmond, P.; Harris, S. E.; Lemyre, E.; Schumann, G.; Bourgeron, T.; Pausova, Z.; Paus, T.; Karama, S.; Lippe, S.; Deary, I.; Almasy, L.; Labbe, A.; Glahn, D.; Greenwood, C. M.; Jacquemont, S.
10.1101/2020.04.03.024554 — genetics — Posted on 2020-10-05
3837 A cutting-edge approach unravels a novel role for CDK6 in leukemic progenitor cells
Doma, E.; Mayer, I. M.; Brandstoetter, T.; Maurer, B.; Grausenburger, R.; Menzl, I.; Zojer, M.; Hoelbl-Kovacic, A.; Carlsson, L.; Heller, G.; Kollmann, K.; Sexl, V.
10.1101/2020.10.05.325886 — cancer biology — Posted on 2020-10-05
3841 Ab-Ligity: Identifying sequence-dissimilar antibodies that bind to the same epitope
Wong, W. K.; Robinson, S. A.; Bujotzek, A.; Georges, G.; Lewis, A. P.; Shi, J.; Snowden, J.; Taddese, B.; Deane, C.
10.1101/2020.03.24.004051 — bioinformatics — Posted on 2020-10-05
3844 Insect herbivory on urban trees: Complementary effects of tree neighbours and predation
Stemmelen, A.; Paquette, A.; Benot, M.-L.; Kadiri, Y.; Jactel, H.; Castagneyrol, B.
10.1101/2020.04.15.042317 — ecology — Posted on 2020-10-05
3847 Signal separability in integrated neurophotonics
Yatsenko, D.; Moreaux, L. C.; Choi, J.; Tolias, A.; Shepard, K. L.; Roukes, M. L.
10.1101/2020.09.27.315556 — neuroscience — Posted on 2020-10-05
3848 The effects of age on resting-state BOLD signal variability is explained by cardiovascular and cerebrovascular factors
Tsvetanov, K. A.; Henson, R. N.; Jones, P. S.; Mutsaerts, H.-J.; Fuhrmann, D.; Tyler, L. K.; Cambridge Centre for Ageing and Neuroscience, Cam-CAN, ; Rowe, J. B.
10.1101/836619 — neuroscience — Posted on 2020-10-05
3854 Standardized and reproducible measurement of decision-making in mice
The International Brain Laboratory, ; Aguillon, V.; Angelaki, D.; Bayer, H. M.; Bonacchi, N.; Carandini, M.; Cazettes, F.; Churchland, A. K.; Chapuis, G.; Dan, Y.; Dewitt, E.; Faulkner, M.; Hamish, F.; Haetzel, L.; Hausser, M.; Hofer, S.; Hu, F.; Khanal, A.; Krasniak, C.; Laranjeira, I.; Mainen, Z.; Meijer, G.; Miska, N.; Mrsic-Flogel, T.; Noel, J.-P.; Pan Vazquez, A.; Sanders, J.; Socha, K.; Terry, R.; Urai, A.; Vergara, H. M.; Wells, M.; Wilson, C.; Witten, I.; Wool, L.; Zador, A.
10.1101/2020.01.17.909838 — neuroscience — Posted on 2020-10-04
3855 Statistical Pitfalls in Brain Age Analyses
Butler, E. R.; Chen, A. A.; Ramadan, R.; Le, T. T.; Ruparel, K.; Moore, T. M.; Satterthwaite, T. D.; Zhang, F.; Shou, H.; Gur, R. C.; Nichols, T. E.; Shinohara, R. T.
10.1101/2020.06.21.163741 — neuroscience — Posted on 2020-10-04
3856 Somatic chromosomal number alterations affecting driver genes inform in-vitro and clinical drug response in high-grade serous ovarian cancer
Correia Martins, F.; Couturier, D.-L.; Santiago, I.; Sauer, C.; Vias, M.; Angelova, M.; Sanders, D.; Piskorz, A.; Hall, J.; Hosking, K.; Amirthanayagam, A.; Cosulich, S.; Carnevalli, L.; Davies, B.; Watkins, T. B. K.; Funingana, G.; Bolton, H.; Haldar, K.; Latimer, J.; Baldwin, P.; Crawford, R.; Eldridge, M.; Basu, B.; Jimenez-Linan, M.; McGranahan, N.; Litchfield, K.; Shah, S.; McNeish, I.; Caldas, C.; Evan, G.; Swanton, C.; Brenton, J. D.
10.1101/2020.10.04.325365 — cancer biology — Posted on 2020-10-04
3857 Preneoplastic lesions fimbria pan-proteomic studies establish the fimbriectomy benefit for BRCA1/2 patients and identify early diagnosis markers of HGSC
Wisztorski, M.; saudemont, P.; aboulouard, s.; cardon, t.; narducci, f.; robin, y.-m.; Lemaire, A.-s.; Bertin, D.; Kobeissy, F.; Leblanc, E.; Fournier, I.; Salzet, M.
10.1101/2020.10.04.325100 — cancer biology — Posted on 2020-10-04
3860 Gene-rich X chromosomes implicate intragenomic conflict in the evolution of bizarre genetic systems
Anderson, N.; Jaron, K. S.; Hodson, C. N.; Couger, M. B.; Sevcik, J.; Pirro, S.; Ross, L.; Roy, S. W.
10.1101/2020.10.04.325340 — evolutionary biology — Posted on 2020-10-04
3862 The Endoplasmic Reticulum Proteostasis Regulator ATF6 is Essential for Human Cone Photoreceptor Development
Kroeger, H.; Grandjean, J. M.; Chiang, W.-C. J.; Bindels, D.; Mastey, R.; Okalova, J.; Nguyen, A.; Powers, E. T.; Kelly, J. W.; Grimsey, N. J.; Michaelides, M.; Carroll, J.; Wiseman, L.; Lin, J.
10.1101/2020.10.04.325019 — developmental biology — Posted on 2020-10-04
3864 An affinity-matured human monoclonal antibody targeting fusion loop epitope of dengue virus with in vivo therapeutic potency
Kotaki, T.; Kurosu, T.; Grinyo, A.; Davidson, E.; Churrotin, S.; Okabayashi, T.; Puiprom, O.; Mulyatno, K. C.; Sucipto, T. H.; Doranz, B.; Ono, K.-i.; Soegijanto, S.; Kameoka, M.
10.1101/2020.10.03.324731 — microbiology — Posted on 2020-10-04
3865 CXCL10+ peripheral activation niches couple preferred sites of Th1 entry with optimal APC encounter
Prizant, H.; Patil, N.; Negatu, S.; McGurk, A.; Leddon, S. A.; Hughson, A.; McRae, T. D.; Gao, Y.; Livingstone, A. M.; Groom, J. R.; Luster, A. D.; Fowell, D. J.
10.1101/2020.10.04.324525 — immunology — Posted on 2020-10-04
3867 Peripheral kappa opioid receptor activation drives cold hypersensitivity in mice
Madasu, M. K.; Thang, L. V.; Chilukuri, P.; Palanisamy, S.; Arackal, J. S.; Sheahan, T. D.; Foshage, A. M.; Houghten, R. A.; McLaughlin, J. P.; McCall, J. G.; Al-Hasani, R.
10.1101/2020.10.04.325118 — neuroscience — Posted on 2020-10-04
3869 Discovery of tREP-18, a novel class of tRNA encoded peptide with potent leishmanicidal activity
Chakrabarti, A.; Kaushik, M.; Khan, J.; Soota, D.; Kalairasan, P.; Saini, S.; Manvati, S.; Singhal, J.; Ranganathan, A.; Pati, S.; Dhar, P.; Singh, S.
10.1101/2020.10.04.325217 — synthetic biology — Posted on 2020-10-04
3870 Benchmarking ensemble docking methods as a scientific outreach project
Gan, J. L.; Kumar, D.; Chen, C.; Taylor, B. C.; Jagger, B. R.; Amaro, R. E.; Lee, C. T.
10.1101/2020.10.02.324343 — scientific communication and education — Posted on 2020-10-04
3874 A polymer gel index-matched to water enables diverse applications in fluorescence microscopy
Han, X.; Su, Y.; White, H.; O'Neill, K. M.; Morgan, N. Y.; Christensen, R.; Potarazu, D.; Vishwasrao, H. D.; Xu, S.; Sun, Y.; Huang, S.-y.; Moyle, M. W.; Dai, Q.; Pommier, Y.; Giniger, E.; Albrecht, D. R.; Probst, R.; Shroff, H.
10.1101/2020.10.04.324996 — bioengineering — Posted on 2020-10-04
3877 Efficient culture of SARS-CoV-2 in human hepatoma cells enhances viability of the virus in human lung cancer cell lines permitting the screening of antiviral compounds
Ramirez, S.; Fernandez-Antunez, C.; Pham, L. V.; Ryberg, L. A.; Feng, S.; Pedersen, M. S.; Mikkelsen, L. S.; Belouzard, S.; Dubuisson, J.; Gottwein, J. M.; Fahnoe, U.; Bukh, J.
10.1101/2020.10.04.325316 — microbiology — Posted on 2020-10-04
3880 Role of 5-HT2C receptors in zebrafish alarm reactions and post-exposure behavior
do Carmo Silva, R. X.; do Nascimento, B. G.; da Silva Chaves, S. N.; Herculano, A. M.; Lima-Maximino, M.; Maximino, C.
10.1101/2020.10.04.324202 — neuroscience — Posted on 2020-10-04
3881 Omnitemporal choreographies of IP3R and all five STIM/Orai underlie the complexity of mammalian Ca2+ signaling
Emrich, S. M.; Yoast, R. E.; Xin, P.; Arige, V.; Wagner, L. E.; Hempel, N.; Gill, D. L.; Sneyd, J.; Yule, D. I.; Trebak, M.
10.1101/2020.10.04.325480 — physiology — Posted on 2020-10-04
3882 High-Throughput Analysis of Lung Immune Cells in a Murine Model of Rheumatoid Arthritis-Associated Lung Disease
Gaurav, R.; Mikuls, T. R.; Thiele, G. M.; Nelson, A. J.; Niu, M.; Guda, C.; Eudy, J. D.; Barry, A. E.; Wyatt, T. A.; Romberger, D. J.; Duryee, M. J.; England, B. R.; Poole, J. A.
10.1101/2020.10.02.323394 — immunology — Posted on 2020-10-04
3883 Development of Optically-Controlled "Living Electrodes" with Long-Projecting Axon Tracts for a Synaptic Brain-Machine Interface
Adewole, D. O.; Struzyna, L. A.; Burrell, J. C.; Harris, J. P.; Nemes, A. D.; Petrov, D.; Kraft, R. H.; Chen, H. I.; Serruya, M. D.; Wolf, J. A.; Cullen, D. K.
10.1101/333526 — bioengineering — Posted on 2020-10-04
3886 Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity
Specht, H.; Emmott, E.; Petelski, A.; Huffman, R. G.; Perlman, D. H.; Serra, M.; Kharchenko, P.; Koller, A.; Slavov, N.
10.1101/665307 — immunology — Posted on 2020-10-04
3888 Fast oscillations >40Hz localize the epileptogenic zone: an electrical source imaging study using high-density electroencephalography
Avigdor, T.; Abdallah, C.; von Ellenrieder, N.; Rubino, A.; Lo Russo, G.; Hedrich, T.; Bernhardt, B.; Nobili, L.; Grova, C.; Frauscher, B.
10.1101/2020.03.02.973602 — neuroscience — Posted on 2020-10-04
3889 Strengthening of marine amphipod DNA barcode libraries for environmental monitoring
PrasannaKumar, C.; Manikantan, G.; Vijaylaxmi, J.; Gunalan, B.; Manokaran, S.; Pugazhvendan, S. R.
10.1101/2020.08.26.268896 — zoology — Posted on 2020-10-04
3890 Asprosin Neutralizing Antibodies as a Treatment for Metabolic Syndrome
Mishra, I.; Duerrschmid, C.; Ku, Z.; Xie, W.; Silva, E. S.; Hoffman, J.; Xin, W.; Zhang, N.; An, Z.; Chopra, A.
10.1101/2020.09.15.298489 — physiology — Posted on 2020-10-04
3894 Role for the Na+/K+ ATPase α 3 subunit in folding and lamination of the human neocortex
Smith, R. S.; Florio, M.; Akula, S.; Neil, J.; Wang, Y.; Hill, R. S.; Goldman, M.; Mullally, C.; Reed, N.; Bello-Espinosa, L.; Sarnat, L. F.; Monteiro, F.; Erasmo, C.; Pinto e Vairo, F.; Morava, E.; Barkovich, A. J.; Gonzalez-Heydrich, J.; Brownstein, C.; McCarroll, S.; Walsh, C. A.
10.1101/2020.10.03.319137 — neuroscience — Posted on 2020-10-04
3896 Dynamic characteristics rather than static hubs are important in biological networks
Kühlwein, S. D.; Ikonomi, N.; Schwab, J. D.; Kraus, J. M.; Rudolph, K. L.; Pfister, A.; Schuler, R.; Kühl, M.; Kestler, H. A.
10.1101/2020.09.30.320259 — bioinformatics — Posted on 2020-10-04
3897 A patient-designed tissue-engineered model of the infiltrative glioblastoma microenvironment
Cornelison, R. C.; Yuan, J. X.; Tate, K. M.; Petrosky, A.; Beeghly, G. F.; Bloomfield, M.; Schwager, S. R.; Berr, A. L.; Cimini, D.; Bafakih, F. F.; Mandell, J. W.; Purow, B. W.; Horton, B. J.; Munson, J.
10.1101/2020.10.02.322735 — bioengineering — Posted on 2020-10-04
3898 Neurogenetic and genomic approaches reveal roles for Dpr/DIP cell adhesion molecules in Drosophila reproductive behavior
Arbeitman, M.; Brovero, S. G.; Fortier, J. C.; Hu, H.; Lovejoy, P. C.; Newell, N. R.; Palmateer, C.; Tzeng, R.-Y.; Lee, P.-T.; Zinn, K.
10.1101/2020.10.02.323477 — genomics — Posted on 2020-10-04
3899 Diversity and asynchrony in soil microbial communities stabilizes ecosystem functioning
Wagg, C.; Hautier, Y.; Pellkofer, S.; Banerjee, S.; Schmid, B.; van der Heijden, M.
10.1101/2020.10.02.324012 — ecology — Posted on 2020-10-04
3900 Strong functional divergence of tropical reef fish assemblages along the global diversity gradient
Parravicini, V.; Bender, M.; Villeger, S.; Leprieur, F.; Donati, G.; Pellissier, L.; Floeter, S.; Rezende, E.; Mouillot, D.; Kulbicki, M.
10.1101/2020.09.18.303008 — ecology — Posted on 2020-10-04
3904 Inhibitory synaptic vesicles have unique dynamics and exocytosis properties
Park, C.; Chen, X.; Tian, C.-L.; Park, G. N.; Chenouard, N.; Lee, H.; Yeo, X. Y.; Jung, S.; Bi, G.; Tsien, R. W.; Park, H.
10.1101/2020.09.21.289314 — neuroscience — Posted on 2020-10-04
3905 Variability in the diet diversity of catfish highlighted through DNA barcoding
PrasannaKumar, C.; Iyyapparajanarasimapallavan, G.; Ashiq Ur Rahman, M.; Mohanchander, P.; Sudhakar, T.; Kadharsha, K.; Feroz Khan, K.; Vijaylaxmi, J.; Prasanthi, N.; Manokaran, S.
10.1101/2020.09.18.268888 — zoology — Posted on 2020-10-04
3907 THE MODEL OF PPARγ DOWNREGULATED SIGNALING IN PSORIASIS
Sobolev, V.; Nesterova, A.; Soboleva, A.; Dvoriankova, E.; Piruzyan, A.; Mildzikhova, D.; Korsunskaya, I.; Svitich, O.
10.1101/2020.09.01.274753 — bioinformatics — Posted on 2020-10-04
3914 Strain Level Microbial Detection and Quantification with Applications to Single Cell Metagenomics
Zhu, K.; Robinson, W.; Schaffer, A. A.; Xu, J.; Ruppin, E.; Ergun, F.; Ye, Y.; Sahinalp, C.
10.1101/2020.06.12.149245 — bioinformatics — Posted on 2020-10-04
3915 Birth timing after the long feeding migration in elephant seals
Condit, R.; Beltran, R. S.; Robinson, P. W.; Crocker, D. E.; Costa, D. P.
10.1101/2020.10.02.324210 — animal behavior and cognition — Posted on 2020-10-04
3920 Leptin-receptor neurons in the dorsomedial hypothalamus regulate the timing of circadian rhythms in feeding and metabolism in mice
Faber, C. L.; Deem, J.; Phan, B. A.; Doan, T. P.; Ogimoto, K.; Mirzadeh, Z.; Schwartz, M. W.; Morton, G. J.
10.1101/2020.10.03.324871 — neuroscience — Posted on 2020-10-04
3921 Bayes Estimate of Primary Threshold in Cluster-wise fMRI Inferences
Ge, Y.; Hare, S.; Chen, G.; Waltz, J.; Kochunov, P.; Hong, E.; Chen, S.
10.1101/2020.10.03.324962 — neuroscience — Posted on 2020-10-04
3922 Spatial representations in macaque hippocampal formation
Mao, D.; Avila, E.; Caziot, B.; Laurens, J.; Dickman, D.; Angelaki, D.
10.1101/2020.10.03.324848 — neuroscience — Posted on 2020-10-04
3925 A transposon surveillance mechanism that safeguards plant male fertility during stress
Gutierrez-Marcos, J.; Lee, Y.-S.; Maple, R.; Durr, J.; Dawson, A.; Tamim, S.; Meyers, B. C.; del Genio, C.; Papareddy, R.; Luo, A.; Lamb, J.; Sylvester, A. W.; Birchler, J. A.; Nodine, M. D.; Rouster, J.
10.1101/2020.10.03.324764 — plant biology — Posted on 2020-10-04
3932 Decolonizing Psocopteran Systematics: Holarctic Lineages Cannot Inform Diversity and Evolution in Tropics
Sarria-Rodriguez, V.; Gonzalez-Obando, R.; Rivera-Franco, N.; Cardenas-Henao, H.; Roman-Palacios, C.
10.1101/2020.10.02.324277 — evolutionary biology — Posted on 2020-10-04
3937 Sedimentation rate and organic matter dynamics shape microbiomes across a continental margin
Bhattacharya, S.; Mapder, T.; Fernandes, S.; Roy, C.; Sarkar, J.; Rameez, M. J.; Mandal, S.; Sar, A.; Chakraborty, A. K.; Mondal, N.; Dam, B.; Peketi, A.; Chakraborty, R.; Mazumdar, A.; Ghosh, W.
10.1101/2020.10.03.324590 — microbiology — Posted on 2020-10-03
3940 A single cell view of the transcriptome during lateral root initiation in Arabidopsis thaliana
Gala, H. P.; Lanctot, A. P.; Jean-Baptiste, K.; Guiziou, S.; Chu, J. C.; Zemke, J. E.; George, W.; Queitsch, C.; Cuperus, J.; Nemhauser, J.
10.1101/2020.10.02.324327 — plant biology — Posted on 2020-10-03
3942 Genetic mapping of the early responses to salt stress in Arabidopsis thaliana
Awlia, M.; Alshareef, N.; Saber, N.; Korte, A.; Oakey, H.; Panzarova, K.; Trtilek, M.; Negrao, S.; Tester, M.; Julkowska, M. M.
10.1101/2020.10.02.324178 — plant biology — Posted on 2020-10-03
3944 On-tissue spatially-resolved glycoproteomics guided by N-glycan imaging reveal global dysregulation of canine glioma glycoproteomic landscape
Malaker, S. A.; Quanico, J.; Raffo Romero, A.; Kobeissy, F.; Aboulouard, S.; Bertozzi, C. R.; Fournier, I.; Salzet, M.
10.1101/2020.10.02.324434 — cancer biology — Posted on 2020-10-03
3948 The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals
Torrence, M. E.; MacArthur, M. R.; Hosios, A. M.; Valvezan, A.; Asara, J. M.; Mitchell, J. R.; Manning, B. D.
10.1101/2020.10.03.324186 — cell biology — Posted on 2020-10-03
3949 Proteomic analysis of microtubule inner proteins (MIPs) in Rib72 null Tetrahymena cells reveals functional MIPs
Fabritius, A. S.; Bayless, B. A.; Li, S.; Stoddard, D.; Heydeck, W.; Ebmeier, C. C.; Anderson, L.; Gunnels, T.; Nachiappan, C.; Whittall, J. B.; Old, W.; Agard, D.; Nicastro, D.; Winey, M.
10.1101/2020.10.02.324467 — molecular biology — Posted on 2020-10-03
3954 Malignant astrocyte swelling and impaired glutamate clearance drive the expansion of injurious spreading depolarization foci
Menyhart, A.; Frank, R.; Farkas, A. E.; Sule, Z.; Varga, V. E.; Nyul-Toth, A.; Meiller, A.; Ivankovits-Kiss, O.; Lemale, C. L.; Szabo, I.; Toth, R.; Zolei-Szenasi, D.; Woitzik, J.; Marinesco, S.; Krizbai, I. A.; Bari, F.; Dreier, J. P.; Farkas, E.
10.1101/2020.10.02.324103 — neuroscience — Posted on 2020-10-03
3957 Generating new FANCA-deficient HNSCC cell lines by genomic editing recapitulate the cellular phenotypes of Fanconi anemia
Errazquin, R.; Sieiro, E.; Moreno, P.; Ramirez, M. J.; Lorz, C.; Peral, J.; Casado, J. A.; Roman-Rodriguez, F. J.; Hanenber, H.; Rio, P.; Surralles, J.; Segrelles, C.; Garcia-Escudero, R.
10.1101/2020.10.03.324921 — cancer biology — Posted on 2020-10-03
3958 Actin crosslinker competition and sorting drive emergent GUV size-dependent actin network architecture
Bashirzadeh, Y.; Redford, S. A.; Lorpaiboon, C.; Groaz, A.; Litschel, T.; Schwille, P.; Hocky, G. M.; Dinner, A.; Liu, A. P.
10.1101/2020.10.03.322354 — biophysics — Posted on 2020-10-03
3963 Loss of α-actinin-3 during human evolution provides superior cold resilience and muscle heat generation
Wyckelsma, V. L.; Venckunas, T.; Houweling, P. J.; Schlittler, M.; Lauschke, V. M.; Tiong, C. F.; Wood, H.; Ivarsson, N.; Paulauskas, H.; Eimantas, N.; Andersson, D. C.; North, K. N.; Brazaitis, M.; Westerblad, H.
10.1101/2020.10.03.323964 — genetics — Posted on 2020-10-03
3964 High Throughput RNA Sequencing of Mice Retina Reveals Metabolic Pathways Involved in the Gut-Retina Axis
Nadeem, U.; Xie, B.; Movahedan, A.; D'Souza, M.; Barba, H.; Deng, N.; Leonne, V.; Chang, E. B.; Sulakhe, D.; Skondra, D.
10.1101/2020.10.01.318949 — molecular biology — Posted on 2020-10-03
3965 CIGAR-seq, a CRISPR/Cas-based method for unbiased screening of novel mRNA modification regulators
Fang, L.; Wang, W.; Li, G.; Zhang, L.; Li, J.; Gan, D.; Yang, J.; Tang, Y.; Ding, Z.; Zhang, M.; Zhang, W.; Deng, D.; Song, Z.; Zhu, Q.; Cui, H.; Hu, Y.; Chen, W.
10.1101/2020.10.03.324715 — molecular biology — Posted on 2020-10-03
3966 Differential Disease Severity and Whole Genome Sequence Analysis for Human Influenza A/H1N1pdm Virus in 2015-2016 Influenza Season
Liu, H.; Gong, Y.-N.; Shaw-Saliba, K.; Mehoke, T.; Evans, J.; Liu, Z.-Y.; Lewis, M.; Sauer, L.; Thielen, P.; Rothman, R.; Chen, K.-F.; Pekosz, A.
10.1101/2020.02.20.957068 — microbiology — Posted on 2020-10-03
3967 Spermidine and spermine are the natural substrates of the Acinetobacter baumannii AmvA multidrug efflux pump
Short, F. L.; Liu, Q.; Ashwood, H. E.; Naidu, V.; Li, L.; Mabbutt, B. C.; Hassan, K. A.; Paulsen, I. T.
10.1101/2020.10.02.324624 — microbiology — Posted on 2020-10-03
3968 Modulation of early host innate immune response by a Fowlpox virus (FWPV) lateral body protein
Giotis, E. S.; Laidlaw, S. M.; Bidgood, S. R.; Albrecht, D.; Burden, J. J.; Robey, R. C.; Mercer, J.; Skinner, M. A.
10.1101/2020.10.02.324418 — microbiology — Posted on 2020-10-03
3969 Identifying persistent structures in multiscale 'omics data
Zheng, F.; Zhang, S.; Churas, C.; Pratt, D.; Bahar, I.; Ideker, T.
10.1101/2020.06.16.151555 — systems biology — Posted on 2020-10-03
3972 Natural selection and the advantage of recombination
Gerrish, P. J.; Galeota-Sprung, B.; Cordero, F.; Sniegowski, P. D.; Colato, A.; Hengartner, N. W.; Vejalla, V.; Chevalier, J.; Ycart, B.
10.1101/2020.08.28.271486 — evolutionary biology — Posted on 2020-10-03
3975 Differential encoding in prefrontal cortex projection neuron classes across cognitive tasks
Lui, J. H.; Nguyen, N. D.; Grutzner, S. M.; Darmanis, S.; Peixoto, D.; Wagner, M. J.; Allen, W. E.; Kebschull, J. M.; Richman, E. B.; Ren, J.; Newsome, W. T.; Quake, S. R.; Luo, L.
10.1101/2020.03.14.991018 — neuroscience — Posted on 2020-10-03
3980 The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis
Menon, S. L.; Goldfarb, D.; Ho, C. T.; Cloer, E. W.; Boyer, N. P.; Hardie, C.; Bock, A. J.; Johnson, E. C.; Anil, J.; Major, M.; Gupton, S. L.
10.1101/2020.10.02.323980 — cell biology — Posted on 2020-10-03
3983 ScRNA-seq reveals tumor microenvironment remodeling induced by local intervention-based immunotherapy
Hoover, A. R.; Liu, K.; Devette, C. I.; Krawic, J. R.; West, C. L.; Medcalf, D.; Welm, A. L.; Sun, X.-H.; Hildebrand, W. H.; Chen, W. R.
10.1101/2020.10.02.323006 — cell biology — Posted on 2020-10-03
3984 The branching code: a model of actin-driven dendrite arborisation
Stürner, T.; Castro, A. F.; Philipps, M.; Cuntz, H.; Tavosanis, G.
10.1101/2020.10.01.322750 — neuroscience — Posted on 2020-10-03
3985 Testcrosses are an efficient strategy for identifying cis regulatory variation: Bayesian analysis of allele specific expression (BASE)
Miller, B.; Morse, A.; Borgert, J. E.; Liu, Z.; Sinclair, K.; Gamble, G.; Zou, F.; Newman, J.; Leon-Novelo, L.; Marroni, F.; McIntyre, L.
10.1101/2020.10.01.322362 — bioinformatics — Posted on 2020-10-03
3986 Single Cell Analysis of Regions of Interest (SCARI) using a novel photoswitchable tag
van der Leun, A. M.; Hoekstra, M. E.; Reinalda, L.; Scheele, C. L.; Toebes, M.; van de Graaff, M. J.; Li, H.; Bercovich, A.; Lubling, Y.; David, E.; Thommen, D. S.; Tanay, A.; van Rheenen, J.; Amit, I.; van Kasteren, S. I.; Schumacher, T. N.
10.1101/2020.10.02.291096 — bioengineering — Posted on 2020-10-03
3987 Identification of genetic heterogeneity in a South Indian family affected by primary open-angle glaucoma.
Mohd, H. S.; Kumaran, M.; Chermakani, P.; Abdul Kader, M.; R, R.; Subbiah., K. R.; Devarajan, B.; Periasamy, S.
10.1101/2020.09.21.306191 — genomics — Posted on 2020-10-03
3989 Emerging strains of watermelon mosaic virus in Southeastern France: model-based estimation of the dates and places of introduction
Roques, L.; Desbiez, C.; Berthier, K.; Soubeyrand, S.; Walker, E.; Klein, E. K.; Garnier, J.; Moury, B.; Papaix, J.
10.1101/2020.10.01.322693 — ecology — Posted on 2020-10-03
3991 Widespread agrochemicals differentially affect zooplankton biomass and community structure
Hebert, M.-P.; Fugere, V.; Beisner, B.; Barbosa da Costa, N.; Barrett, R.; Bell, G.; Shapiro, J.; Yargeau, V.; Gonzalez, A.; Fussmann, G.
10.1101/2020.10.01.322370 — ecology — Posted on 2020-10-03
3995 A standardized and reproducible method to measure decision-making in mice
The International Brain Laboratory, ; Aguillon, V.; Angelaki, D.; Bayer, H. M.; Bonacchi, N.; Carandini, M.; Cazettes, F.; Churchland, A. K.; Chapuis, G.; Dan, Y.; Dewitt, E.; Faulkner, M.; Hamish, F.; Haetzel, L.; Hausser, M.; Hofer, S.; Hu, F.; Khanal, A.; Krasniak, C.; Laranjeira, I.; Mainen, Z.; Meijer, G.; Miska, N.; Mrsic-Flogel, T.; Noel, J.-P.; Pan Vazquez, A.; Sanders, J.; Socha, K.; Terry, R.; Urai, A.; Vergara, H. M.; Wells, M.; Wilson, C.; Witten, I.; Wool, L.; Zador, A.
10.1101/2020.01.17.909838 — neuroscience — Posted on 2020-10-03
3996 Neural tube patterning: from a minimal model for rostrocaudal patterning towards an integrated 3D model
Brambach, M.; Ernst, A.; Nolbrant, S.; Drouin-Ouellet, J.; Kirkeby, A.; Parmar, M.; Olariu, V.
10.1101/2020.10.02.323535 — systems biology — Posted on 2020-10-02
3999 TOR coordinates with transcriptional and chromatin machinery to regulate thermotolerance and thermomemory
Sharma, M.; K, M. J.; Shukla, B. N.; Sharma, M.; Awasthi, P.; Mahtha, S. K.; Yadav, G.; Laxmi, A.
10.1101/2020.07.28.224634 — plant biology — Posted on 2020-10-03
4010 Development and validation of nanobodies specific to the oncogenic phosphatase Protein Tyrosine Phosphatase 4A3 (PTP4A3 or PRL-3)
Smith, C. N.; Wei, M.; Williamson, Z. A.; Chernyavskyay, Y.; Chow, K. M.; Hersh, L. B.; Korotkov, K. V.; Blackburn, J. S.
10.1101/2020.10.02.311787 — biochemistry — Posted on 2020-10-03
4012 South Asian patient population genetics reveal strong founder effects and high rates of homozygosity - new resources for precision medicine
Wall, J.; Sathirapongsasuti, J. F.; Gupta, R.; Barik, A.; Rai, R. K.; Rasheed, A.; Radha, V.; Belsare, S.; Menon, R.; Phalke, S.; Mittal, A.; Fang, J.; Tanneeru, D.; Robinson, J.; Chaudhary, R.; Fuchsberger, C.; Forer, L.; Schoenherr, S.; Bei, Q.; Bhangale, T.; Tom, J.; Gadde, S. G. K.; V, P. B.; Naik, N. K.; Wang, M.; Kwok, P.-Y.; Khera, A. V.; Lakshmi, B. R.; Butterworth, A.; Danesh, J.; Seshagiri, S.; Kathiresan, S.; Ghosh, A.; Mohan, V.; Chowdhury, A.; Saleheen, D.; Stawiski, E.; Peterson, A. S.
10.1101/2020.10.02.323238 — genomics — Posted on 2020-10-02
4017 The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis
Gupton, S. L.; Goldfarb, D.; Ho, T.; Cloer, E. W.; Boyer, N. P.; Hardie, C.; Bock, A. J.; Johnson, E. C.; Anil, J.; Major, M.; Gupton, S. L.
10.1101/2020.10.02.323980 — cell biology — Posted on 2020-10-02
4018 Transposable element expression at unique loci in single cells with CELLO-seq
Marioni, J. C.; Berrens, R. V.; Yang, A.; Lun, A. T.; Laumer, C. E.; Lan, G.; Bieberich, F.; Law, C.-T.; Imaz, M.; Gaffney, D.
10.1101/2020.10.02.322073 — molecular biology — Posted on 2020-10-02
4019 High Throughput RNA Sequencing of Mice Retina Reveals Metabolic Pathways Involved in the Gut-Retinal Axis
Nadeem, U.; Skondra, D.; Xie, B.; Movahedan, A.; D'Souza, M.; Barba, H.; Deng, N.; Leonne, V.; Chang, E. B.; Sulakhe, D.
10.1101/2020.10.01.318949 — molecular biology — Posted on 2020-10-02
4020 Flash properties of Gaussia Luciferase are the result of covalent inhibition after a limited number of cycles
Dijkema, F. M.; Nordentoft, M. K.; Didriksen, A. K.; Corneliussen, A. S.; Willemoës, M.; Winther, J. R.
10.1101/2020.10.01.322248 — molecular biology — Posted on 2020-10-02
4022 Two independent approaches converge to the cloning of a new Leptosphaeria maculans avirulence effector gene, AvrLmS-Lep2
Neik, T. X.; Ghanbarnia, K.; Ollivier, B.; Scheben, A.; Severn-Ellis, A.; Larkan, N. J.; Haddadi, P.; Fernando, D. G.; Rouxel, T.; Batley, J.; Borhan, H. M.; Balesdent, M.-H.
10.1101/2020.10.02.322479 — molecular biology — Posted on 2020-10-03
4023 Comparative analysis of temporal transcriptome reveals the relationship between pectin degradation and pathogenicity of defoliating Verticillium dahliae to Upland cotton (Gossypium hirsutum)
Zhang, F.; Zhang, J.; Chen, W.; Liu, X.; Li, C.; Cao, Y.; Zhao, T.; Lu, D.; Hui, Y.; Zhang, Y.; Chen, J.; Zhang, J.; Pepper, A. E.; Yu, J. Z.; Zhu, S.
10.1101/2020.10.02.323402 — microbiology — Posted on 2020-10-03
4024 Accurate Microbiome Sequencing with Synthetic Long Read Sequencing
Chung, N.; Van Goethem, M. W.; Preston, M. A.; Lhota, F.; Cerna, L.; Garcia-Pichel, F.; Fernandes, V. M. C.; Giraldo-Silva, A.; Kim, H. S.; Hurowitz, E.; Balamotis, M.; Wu, I.; Ben Yehezkel, T.
10.1101/2020.10.02.324038 — microbiology — Posted on 2020-10-03
4025 Monocyte-derived alveolar macrophages mediate resistance to migrating helminths through depletion of arginine availability
Chen, F.; El Naccache, D. W.; Ponessa, J.; Lemenze, A.; Espinosa, V.; Wu, W.; Lothstein, K.; Jin, L.; Rivera, A.; Siracusa, M.; Gause, W.
10.1101/2020.10.02.322388 — immunology — Posted on 2020-10-02
4028 Cellular Anatomy of the Mouse Primary Motor Cortex
Munoz-Castaneda, R.; Zingg, B.; Matho, K. S.; Wang, Q.; Chen, X.; Foster, N. N.; Narasimhan, A.; Li, A.; Hirokawa, K. E.; Huo, B.; Banerjee, S.; Korobkova, L.; Park, C. S.; Park, Y.-G.; Bienkowski, M. S.; Chon, U.; Wheeler, D. W.; Li, X.; Wang, Y.; Kelly, K.; An, X.; Attili, S. M.; Bowman, I.; Bludova, A.; Cetin, A.; Ding, L.; Drewes, R.; D'Orazi, F.; Elowsky, C.; Fischer, S.; Galbavy, W.; Gao, L.; Gillis, J.; Groblewski, P. A.; Gou, L.; Hahn, J. D.; Hatfield, J. T.; Hintiryan, H.; Huang, J.; Kondo, H.; Kuang, X.; Lesnar, P.; Li, X.; Li, Y.; Lin, M.; Liu, L.; Lo, D.; Mizrachi, J.; Mok, S.; Nae
10.1101/2020.10.02.323154 — neuroscience — Posted on 2020-10-02
4029 Aberrant ventral dentate gyrus structure and function in individuals susceptible to post-traumatic stress disorder
Dirven, B. C. J.; van der Geugten, D.; van Bodegom, M.; Madder, L.; van Agen, L.; Homberg, J. R.; Kozicz, T.; Henckens, M. J. A. G.
10.1101/2020.10.01.321893 — neuroscience — Posted on 2020-10-02
4030 The underlying mechanisms of improved balance aftershort- and long-term training in older adults
Alizadehsaravi, L.; Koster, R.; Muijres, W.; Maas, H.; Bruijn, S. M.; van Dieen, J. H.
10.1101/2020.10.01.322313 — neuroscience — Posted on 2020-10-02
4037 Dwarf open reading frame (DWORF) peptide is a direct activator of the sarcoplasmic reticulum calcium pump SERCA.
Fisher, M. E.; Bovo, E.; Cho, E. E.; Pribadi, M. P.; Dalton, M. P.; Lemieux, M. J.; Rathod, N.; Aquayo-Ortiz, R.; Espinoza-Fonseca, L. M.; Robia, S. L.; Zima, A. V.; Young, H. S.
10.1101/2020.10.01.322610 — biophysics — Posted on 2020-10-02
4043 Molecular Parallelisms and Divergences Between Human and Canine Mammary Cancer
Lu, X.; Ambreen, S.; Hou, Y.; Guanhan, L.; Zhao, B.; Bao, G.; Song, Y.; Lin, D.; Wu, D.
10.1101/2020.10.01.318188 — genomics — Posted on 2020-10-02
4044 New evidence concerning the genome designations of the AC(DC) tetraploid Avena species
Yan, H.; Ren, Z.; Deng, D.; Yang, K.; Yang, C.; Zhou, P.; Wight, C. P.; Ren, C.; Peng, Y.
10.1101/2020.10.02.323345 — genetics — Posted on 2020-10-02
4054 Temporal expectation hastens decision onset but does not affect evidence quality
van den Brink, R. L.; Murphy, P. R.; Desender, K.; de Ru, N.; Nieuwenhuis, S.
10.1101/2020.01.30.926337 — neuroscience — Posted on 2020-10-02
4056 White matter microstructural changes in short-term learning of a continuous visuomotor sequence
Tremblay, S. A.; Jager, A.-T.; Huck, J.; Giacosa, C.; Beram, S.; Schneider, U.; Grahl, S.; Villringer, A.; Tardif, C. L.; Bazin, P.-L.; Steele, C. J.; Gauthier, C. J.
10.1101/2020.10.02.324004 — neuroscience — Posted on 2020-10-02
4058 A Generative Approach toward Precision Antimicrobial Peptide Design
Ferrell, J. B.; Remington, J. M.; Van Oort, C. M.; Sharafi, M.; Aboushousha, R.; Janssen-Heininger, Y.; Schneebeli, S. T.; Wargo, M. J.; Wshah, S.; Li, J.
10.1101/2020.10.02.324087 — biophysics — Posted on 2020-10-02
4063 The evolutionary dynamics of genetic incompatibilities introduced by duplicated genes in Arabidopsis thaliana
Jiao, W.-B.; Patel, V.; Klasen, J.; Liu, F.; Pecinkova, P.; Ferrand, M.; Gy, I.; Camilleri, C.; Effgen, S.; Koornneef, M.; Pecinka, A.; Loudet, O.; Schneeberger, K.
10.1101/2020.09.21.306035 — evolutionary biology — Posted on 2020-10-02
4067 Molecular analyses reveal consistent food web structure with elevation in rainforest Drosophila - parasitoid communities
Jeffs, C. T.; Terry, J. C. D.; Higgie, M.; Jandova, A.; Konvickova, H.; Brown, J. J.; Lue, C.-H.; Schiffer, M.; O'Brien, E. K.; Bridle, J.; Hrcek, J.; Lewis, O. T.
10.1101/2020.07.21.213678 — ecology — Posted on 2020-10-02
4068 Morphine alleviates pain after heart cryoinjury in zebrafish without impeding regeneration
Lelek, S.; Simoes, M.; Hu, B.; Alameldeen, A. M. A.; Czajkowski, M. T.; Meyer, A. M.; Ferrara, F.; Junker, J. P.; Panakova, D.
10.1101/2020.10.01.322560 — developmental biology — Posted on 2020-10-02
4070 Characterization of the antimicrobial activity of the cell-penetrating peptide TAT-RasGAP317-326
Georgieva, M.; Heinonen, T.; Vitale, A.; Hargraves, S.; Causevic, S.; Pillonel, T.; Eberl, L.; Widmann, C.; Jacquier, N.
10.1101/2020.10.02.321802 — microbiology — Posted on 2020-10-02
4073 Sexually dimorphic influence of the circadian clock gene Bmal1 in the striatum on alcohol intake
de Zavalia, N.; Schottner, K.; Goldsmith, J. A.; Solis, P.; Ferraro, S.; Parent, G.; Amir, S.
10.1101/2020.09.16.299842 — neuroscience — Posted on 2020-10-02
4074 Separable influences of reward on visual processing and choice
Soltani, A.; Rakhshan, M.; Schafer, R. J.; Burrows, B.; Moore, T.
10.1101/2020.04.07.029942 — neuroscience — Posted on 2020-10-02
4075 Relationship between Regional White Matter Hyperintensities and Alpha Oscillations in Older Adults
Kumral, D.; Cesnaite, E.; Beyer, F.; Hofmann, S. M.; Hensch, T.; Sander, C.; Hegerl, U.; Haufe, S.; Villringer, A.; Witte, V.; Nikulin, V.
10.1101/2020.09.04.283200 — neuroscience — Posted on 2020-10-02
4077 Testing theoretical minimal genomes using whole-cell models
Rees-Garbutt, J.; Rightmyer, J.; Chalkley, O.; Marucci, L.; Grierson, C.
10.1101/2020.03.26.010363 — synthetic biology — Posted on 2020-10-02
4078 Purification, characterization and influence on membrane properties of the plant-specific sphingolipids GIPC
Mamode Cassim, A.; Navon, Y.; Gao, Y.; Decossas, M.; Fouillen, L.; Grelard, A.; Nagano, M.; Lambert, O.; Bahammou, D.; van Delft, P.; Maneta-Peyret, L.; Simon-Plas, F.; Heux, L.; Fragneto, G.; Mortimer, J.; Deleu, M.; Lins, L.; Mongrand, S.
10.1101/2020.10.01.313304 — plant biology — Posted on 2020-10-02
4079 Splice-switching of the insulin receptor in rhabdomyosarcoma: Rescuing the IR-B isoform for better treatment options.
Khurshid, S.; Montes, M.; Comiskey, D. F.; Shane, B.; Matsa, E.; Brown, C.; Bid, H. K.; Wang, R.; Houghton, P.; Rigo, F.; Chandler, D.
10.1101/2020.10.02.324053 — cancer biology — Posted on 2020-10-02
4080 Human hypertrophic cardiomyopathy mutation R712L suppresses the working stroke of cardiac myosin and can be rescued by omecamtiv mecarbil
Snoberger, A.; Barua, B.; Atherton, J. L.; Shuman, H.; Forgacs, E.; Goldman, Y. E.; Winkelmann, D. A.; Ostap, E. M.
10.1101/2020.10.02.323782 — biophysics — Posted on 2020-10-02
4086 Rational Tuning of CAR Tonic Signaling Yields Superior T-Cell Therapy for Cancer
Chen, X.; Khericha, M.; Lakhani, A.; Meng, X.; Salvestrini, E.; Chen, L. C.; Shafer, A.; Alag, A.; Ding, Y.; Nicolaou, D.; Park, J. O.; Chen, Y. Y.
10.1101/2020.10.01.322990 — bioengineering — Posted on 2020-10-02
4087 RNA matchmaking remodels lncRNA structure and promotes PRC2 activity
Balas, M. M.; Hartwick, E. W.; Barrington, C.; Roberts, J. T.; Wu, S. K.; Bettcher, R.; Griffin, A. M.; Kieft, J. S.; Johnson, A. M.
10.1101/2020.04.13.040071 — biochemistry — Posted on 2020-10-02
4091 Trophectoderm differentiation to invasive syncytiotrophoblast is induced by endometrial epithelial cells during human embryo implantation
Ruane, P. T.; Garner, T.; Parsons, L.; Babbington, P. A.; Kimber, S. J.; Stevens, A.; Westwood, M.; Brison, D. R.; Aplin, J. D.
10.1101/2020.10.02.323659 — developmental biology — Posted on 2020-10-02
4095 ROS-dependent innate immune mechanisms control Staphylococcus aureus MRSA virulence in the Drosophila larval model
Ramond, E.; Jamet, A.; Ding, X.; Bouvier, C.; Lallemant, L.; He, X.; Arbibe, L.; Coureuil, M.; Charbit, A.
10.1101/2020.10.02.323444 — microbiology — Posted on 2020-10-02
4096 Fine scale sampling unveils diazotroph patchiness in the South Pacific Ocean
Benavides, M.; Conradt, L.; Bonnet, S.; Berman-Frank, I.; Barrillon, S.; Petrenko, A.; Doglioli, A. M.
10.1101/2020.10.02.323808 — microbiology — Posted on 2020-10-02
4097 Bacteriophage Resistance Affects Flavobacterium columnare Virulence Partly via Mutations in Genes Related to Gliding Motility and Type IX Secretion System
Kunttu, H. M.; Runtuvuori-Salmela, A.; Sundell, K.; Wiklund, T.; Middelboe, M.; Landor, L.; Ashrafi, R.; Hoikkala, V.; Sundberg, L.-R.
10.1101/2020.10.02.323337 — microbiology — Posted on 2020-10-02
4098 Intestinal epithelium-derived high density lipoprotein restrains liver injury via the portal vein
Han, Y.-H.; Onufer, E. J.; Huang, L. H.; Czepielewski, R. S.; Warner, B. W.; Randolph, G. J.
10.1101/2020.10.01.322925 — immunology — Posted on 2020-10-02
4099 Genetic or toxicant induced disruption of vesicular monoamine storage and global metabolic profiling in Caenorhabditis elegans
bradner, j.; Kalia, V.; Lau, F.; Sharma, M.; Bucher, M.; Johnson, M.; Chen, M.; Walker, D.; Jones, D.; Miller, G.
10.1101/2020.10.02.324095 — neuroscience — Posted on 2020-10-02
4100 Heat Stress Interferes with Formation of Double-Strand Breaks and Homology Synapsis in Arabidopsis thaliana
Ning, Y.; Liu, Q.; Wang, C.; Qin, E.; Wu, Z.; Wang, M.; Yang, K.; Elesawi, I. E.; Chen, C.; Liu, H.; Qin, R.; Liu, B.
10.1101/2020.10.02.324269 — plant biology — Posted on 2020-10-02
4102 Aged Breast Extracellular Matrix Drives Mammary Epithelial Cells to an Invasive and Cancer-Like Phenotype
Bahcecioglu, G.; Yue, X.; Howe, E.; Guldner, I.; Stack, M. S.; Nakshatri, H.; Zhang, S.; Zorlutuna, P.
10.1101/2020.09.30.320960 — cancer biology — Posted on 2020-10-02
4103 scAAVengr: Single-cell transcriptome-based quantification of engineered AAVs in non-human primate retina
Ozturk, B. E.; Johnson, M. E.; Kleyman, M.; Turunc, S.; He, J.; Jabalameli, S.; Xi, Z.; Visel, M.; Dufour, V. L.; Iwabe, S.; Pompeo Marinho, F.; Aguirre, G. D.; Sahel, J.-A.; Schaffer, D. V.; Pfenning, A. R.; Flannery, J. G.; Beltran, W. A.; Stauffer, W. R.; Byrne, L. C.
10.1101/2020.10.01.323196 — bioengineering — Posted on 2020-10-02
4104 The Phaeodactylum tricornutum Diaminopimelate Decarboxylase was Acquired via Horizontal Gene Transfer from Bacteria and Displays Substrate Promiscuity
Bielinski, V. A.; Brunson, J. K.; Ghosh, A.; Moosburner, M. A.; Garza, E. A.; Fussy, Z.; Bai, J.; McKinnie, S. M. K.; Moore, B.; Allen, A. E.; Almo, S. C.; Dupont, C. L.
10.1101/2020.10.01.322594 — biochemistry — Posted on 2020-10-02
4108 Intrusive Experiences In Post-Traumatic Stress Disorder: Treatment Response Induces Changes In The Effective Connectivity Of The Anterior Insula
Leroy, A.; Very, E.; Birmes, P.; Szaffarczyk, S.; Lopes, R.; Faure, C.; Duhem, S.; Grandgenevre, P.; Warembourg, F.; Vaiva, G.; Jardri, R.
10.1101/2020.10.01.319269 — neuroscience — Posted on 2020-10-02
4109 A Hilbert-based method for processing respiratory timeseries
Harrison, S. J.; Bianchi, S.; Heinzle, J.; Stephan, K. E.; Iglesias, S.; Kasper, L.
10.1101/2020.09.30.321562 — neuroscience — Posted on 2020-10-02
4111 The maize Aliphatic Suberin Feruloyl Transferase genes affect leaf water movement but are dispensable for bundle sheath CO2 concentration
Mertz, R. A.; Ellsworth, P. Z.; Ellsworth, P. V.; Tausta, S. L.; von Caemmerer, S.; Berg, R. H.; Nelson, T.; Carpita, N. C.; Brutnell, T. P.; Cousins, A. B.
10.1101/2020.09.30.321265 — plant biology — Posted on 2020-10-02
4112 The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma
Wu, M.; Hanly, A.; Gibson, F.; Kuang, K. H.; Kalin, J.; Nocco, S.; Collard, M.; Cole, M. W.; Xiao, A.; Agus, F.; Labadorf, A.; Cole, P. A.; Alani, R. M.
10.1101/2020.09.30.320580 — cancer biology — Posted on 2020-10-02
4116 Benefits of crop diversification for biodiversity and ecosystem services
Beillouin, D.; Ben-Ari, T.; Malezieux, E.; Seufert, V.; Makowski, D.
10.1101/2020.09.30.320309 — ecology — Posted on 2020-10-02
4119 Astrocytes close the critical period for visual plasticity
Ribot, J.; Breton, R.; Calvo, C. F.; Moulard, J.; Ezan, P.; Zapata, J.; Samama, K.; Bemelmans, A. P.; Sabatet, V.; Dingli, F.; Loew, D.; Milleret, C.; Billuart, P.; Dallerac, G.; Rouach, N.
10.1101/2020.09.30.321497 — neuroscience — Posted on 2020-10-02
4122 Cross species multi-omics reveals cell wall sequestration and elevated global transcription as mechanisms of boron tolerance in plants
Wang, G.; DiTusa, S. F.; Oh, D.-H.; Herrmann, A. D.; Mendoza-Cozatl, D. G.; O'Neill, M. A.; Smith, A. P.; Dassanayake, M.
10.1101/2020.10.01.321760 — plant biology — Posted on 2020-10-02
4125 The DOE JGI Metagenome Workflow
Clum, A.; Huntemann, M.; Bushnell, B.; Foster, B.; Foster, B.; Roux, S.; Hajek, P.; Varghese, N.; Mukherjee, S.; Reddy, T. B. K.; Daum, C.; Yoshinaga, Y.; Seshadri, R.; Kyrpides, N.; Eloe-Fadrosh, E.; Chen, I.-M. A.; Copeland, A.; Ivanova, N.
10.1101/2020.09.30.320929 — bioinformatics — Posted on 2020-10-02
4127 Nabo - a framework to define leukemia-initiating cells and differentiation in single-cell RNA-sequencing data
Dhapola, P.; Eldeeb, M.; Ugale, A.; Olofzon, R.; Erlandsson, E.; Soneji, S.; Bryder, D.; Karlsson, G.
10.1101/2020.09.30.321216 — bioinformatics — Posted on 2020-10-02
4128 ezGeno: An Automatic Model Selection Package for Genomic Data Analysis
Lin, J.-L.; Hsieh, T.-T.; Tung, Y.-A.; Chen, X.-J.; Hsiao, Y.-C.; Yang, C.-L.; Liu, T.-L.; Chen, C.-Y.
10.1101/2020.09.30.319996 — bioinformatics — Posted on 2020-10-02
4131 Differing total mRNA expression shapes the molecular and clinical phenotype of cancer
Cao, S.; Wang, J. R.; Ji, S.; Yang, P.; Chen, J.; Montierth, M. D.; Shen, J. P.; Lee, J. J.; Guerrero, P. A.; Yu, K.; Livingstone, J.; Bhandari, V.; Hubert, S. M.; Daw, N. C.; Futreal, A.; Efstathiou, E.; Lim, B.; Viale, A.; Zhang, J.; Maitra, A.; Kopetz, S.; Campbell, P.; Speed, T. P.; Boutros, P. C.; Urbanucci, A.; Zhu, H.; Demeulemeester, J.; Van Loo, P.; Wang, W.
10.1101/2020.09.30.306795 — genomics — Posted on 2020-10-02
4132 Genome-wide SNP genotyping of DNA pools identifies untapped landraces and genomic regions that could enrich the maize breeding pool
Arca, M.; Gouesnard, B.; Mary-Huard, T.; Le Paslier, M.-C.; Bauland, C.; Madur, D.; Combes, V.; Charcosset, A. D.; Nicolas, S. D.
10.1101/2020.09.30.321018 — genetics — Posted on 2020-10-02
4136 A time-lagged association between the gut microbiome, nestling growth and nestling survival in wild great tits
Davidson, G. L.; Somers, S. E.; Wiley, N.; Johnson, C. N.; Reichert, M. S.; Ross, R. P.; Stanton, C.; Quinn, J. L.
10.1101/2020.09.30.320804 — ecology — Posted on 2020-10-02
4139 Macrophage metallothioneins participate in the antileishmanial activity of antimonials
Vargas, D. A.; Gregory, D. J.; Koren, R. N.; Zilberstein, D.; Belew, A. T.; El-Sayed, N. M.; Gomez, M. A.
10.1101/2020.09.30.321471 — molecular biology — Posted on 2020-10-02
4140 Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy
Verweij, M.; Hansen, S. G.; Iyer, R.; John, N.; Malouli, D.; Morrow, D.; Scholz, I.; Womack, J.; Abdulhaqq, S.; Gilbride, R. M.; Hughes, C. M.; Ventura, A. B.; Ford, J. C.; Selseth, A. N.; Oswald, K.; Shoemaker, R.; Berkemeier, B.; Borsche, W. J.; Hull, M.; Shao, J.; Sacha, J.; Axthelm, M. K.; Edlefsen, P.; Lifson, J. D.; Picker, L. J.; Früh, K.
10.1101/2020.09.30.321158 — immunology — Posted on 2020-10-02
4141 Circulating Clonally Expanded T Cells Reflect Functions of Tumor Infiltrating T Cells
Lucca, L. E.; Axisa, P.-P.; Lu, B.; Harnett, B.; Jessel, S.; Zhang, L.; Raddassi, K.; Zhang, L.; Olino, K.; Clune, J.; Singer, M.; Kluger, H.; Hafler, D. A.
10.1101/2020.09.30.321240 — immunology — Posted on 2020-10-02
4143 Automatic Measurement of Inner Ear in Different Mammals
Du, Y.; Qin, H.; Liu, C.; Liu, D.; Yuan, S.-l.; Jiang, Q.; Jun Yang, ; Gang Li, ; Honglan Xie, ; Jianguo Zhao, ; Yu, N.; Yang, S.
10.1101/2020.09.30.317941 — neuroscience — Posted on 2020-10-02
4144 Sensory experience selectively reorganizes the late component of evoked responses
Bermudez Contreras, E.; Gomez Palacio-Schjetnan, A.; Luczak, A.; Mohajerani, M. H.
10.1101/2020.09.30.321547 — neuroscience — Posted on 2020-10-02
4146 Ontogenetic Oxycodone Exposure Affects Early-Life Communicative Behaviors, Sensorimotor Reflexes, and Weight Trajectory in Mice
Minakova, E.; Sarafinovska, S.; Mikati, M. O.; Barclay, K. M.; McCullough, K. B.; Dougherty, J. D.; Al-Hasani, R.; Maloney, S. E.
10.1101/2020.09.30.321372 — neuroscience — Posted on 2020-10-02
4156 Potent mouse monoclonal antibodies that block SARS-CoV-2 infection
Guo, Y.; Kawaguchi, A.; Takeshita, M.; Sekiya, T.; Hirohama, M.; Yamashita, A.; the Keio Donner Project, ; Siomi, H.; Murano, K.
10.1101/2020.10.01.323220 — microbiology — Posted on 2020-10-02
4157 Safe and effective two-in-one replicon-and-VLP minispike vaccine for COVID-19
Hennrich, A. A.; Banda, D. H.; Oberhuber, M.; Schopf, A.; Pfaffinger, V.; Wittwer, K.; Sawatsky, B.; Riedel, C.; Pfaller, C. K.; Conzelmann, K.-K.
10.1101/2020.10.02.324046 — microbiology — Posted on 2020-10-02
4158 SARS-CoV-2 infected cells present HLA-I peptides from canonical and out-of-frame ORFs
Weingarten-Gabbay, S.; Klaeger, S.; Sarkizova, S.; Pearlman, L. R.; Chen, D.-Y.; Bauer, M. R.; Taylor, H. B.; Conway, H. L.; Tomkins-Tinch, C. H.; Finkel, Y.; Nachshon, A.; Gentili, M.; Rivera, K. D.; Keskin, D. B.; Rice, C. M.; Clauser, K. R.; Hacohen, N.; Carr, S. A.; Abelin, J. G.; Saeed, M.; Sabeti, P. C.
10.1101/2020.10.02.324145 — immunology — Posted on 2020-10-02
4159 A Multiscale Coarse-grained Model of the SARS-CoV-2 Virion
Yu, A.; Pak, A. J.; He, P.; Monje-Galvan, V.; Casalino, L.; Gaieb, Z.; Dommer, A. C.; Amaro, R. E.; Voth, G. A.
10.1101/2020.10.02.323915 — biophysics — Posted on 2020-10-02
4160 GraphDTA: Predicting drug-target binding affinity with graph neural networks
Nguyen, T.; Le, H.; Quinn, T. P.; Nguyen, T.; Le, T.; Venkatesh, S.
10.1101/684662 — bioinformatics — Posted on 2020-10-02
4164 ER-embedded UBE2J1/RNF26 ubiquitylation complex in spatio-temporal control of the endolysosomal pathway
Cremer, T.; Jongsma, M. L. M.; Trulsson, F.; Vertegaal, A. C. O.; Neefjes, J.; Berlin, I.
10.1101/2020.10.02.323576 — cell biology — Posted on 2020-10-02
4167 Highly responsive single-fluorophoreindicator to explore lactate dynamics in high calcium environments
Galaz, A.; Sandoval, P. Y.; Soto, I.; Hertenstein, H.; Schweizer, J.; Schirmeier, S.; Barros, L. F.; San Martin, A.
10.1101/2020.10.01.322404 — cell biology — Posted on 2020-10-02
4168 Transferrin receptor (Tfr1) ablation in satellite cells impacts skeletal muscle regeneration through the activation of ferroptosis
Ding, H.; Chen, S.; Pan, X.; Dai, X.; Pan, G.; Li, Z.; Mai, X.; Tian, Y.; Zhang, S.; Liu, B.; Cao, G.; Yao, Z.; Yao, X.; Gao, L.; Yang, L.; Chen, X.; Sun, J.; Chen, H.; Han, M.; Yin, Y.; Xu, G.; Li, H.; Wu, W.; Chen, Z.; Lin, J.; Xiang, L.; Lu, Y.; Zhu, X.; Xie, L.
10.1101/2020.10.02.323469 — cell biology — Posted on 2020-10-02
4169 SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface
Bertoglio, F.; Meier, D.; Langreder, N.; Steinke, S.; Rand, U.; Simonelli, L.; Heine, P. A.; Ballmann, R.; Schneider, K.-T.; Roth, K. D. R.; Ruschig, M.; Riese, P.; Eschke, K.; Kim, Y.; Schaeckermann, D.; Pedotti, M.; Kuhn, P.; Zock-Emmenthal, S.; Woehrle, J.; Kilb, N.; Herz, T.; Becker, M.; Grashoff, M.; Wenzel, E. V.; Russo, G.; Kroeger, A.; Brunotte, L.; Ludwig, S.; Fuehner, V.; Kraemer, S. D.; Duebel, S.; Varani, L.; Roth, G.; Cicin-Sain, L.; Schubert, M.; Hust, M.
10.1101/2020.06.05.135921 — biochemistry — Posted on 2020-10-02
4171 A human monoclonal antibody targeting a conserved pocket in the SARS-CoV-2 receptor-binding domain core
Fedry, J.; Hurdiss, D. L.; Wang, C.; Li, W.; Obal, G.; Drulyte, I.; Howes, S. C.; van Kuppeveld, F. J. M.; Förster, F.; Bosch, B. J.
10.1101/2020.09.30.318261 — immunology — Posted on 2020-10-02
4172 Model-guided design of mammalian genetic programs
Muldoon, J. J.; Kandula, V.; Hong, M.; Donahue, P. S.; Boucher, J.; Bagheri, N.; Leonard, J. N.
10.1101/2020.09.30.320853 — synthetic biology — Posted on 2020-10-02
4173 Sex differences in lifespan trajectories and variability of human sulcal and gyral morphology
Diaz-Caneja, C. M.; Alloza, C.; Gordaliza, P. M.; Fernandez Pena, A.; de Hoyos, L.; Santonja, J.; Buimer, E. E. L.; van Haren, N. E. M.; Cahn, W.; Arango, C.; Kahn, R. S.; Hulshoff Pol, H. E.; Schnack, H. G.; Janssen, J.
10.1101/2020.10.02.323592 — neuroscience — Posted on 2020-10-02
4174 Multiscale communication in cortico-cortical networks
Bazinet, V.; Vos de Wael, R.; Hagmann, P.; Bernhardt, B. C.; Misic, B.
10.1101/2020.10.02.323030 — neuroscience — Posted on 2020-10-02
4178 MetaGraph: Indexing and Analysing Nucleotide Archives at Petabase-scale
Karasikov, M.; Mustafa, H.; Danciu, D.; Zimmermann, M.; Barber, C.; Ratsch, G.; Kahles, A.
10.1101/2020.10.01.322164 — bioinformatics — Posted on 2020-10-02
4179 NT-mini, a recombinant tool for the study of Neurotrypsin functionality
Canciani, A.; Capitanio, C.; Stanga, S.; Faravelli, S.; Kienlen-Campard, P.; Forneris, F.
10.1101/2020.10.01.322396 — biochemistry — Posted on 2020-10-02
4180 The history and evolution of the Denisovan-EPAS1 haplotype in Tibetans
Zhang, X.; Witt, K. E.; Ko, A.; Yuan, K.; Xu, S.; Nielsen, R.; Huerta-Sanchez, E.
10.1101/2020.10.01.323113 — evolutionary biology — Posted on 2020-10-02
4182 Chicken cGAS senses fowlpox virus infection and regulates macrophage effector function
Oliveira, M.; Rodrigues, D. R.; Guillory, V.; Kut, E.; Giotis, E. S.; Skinner, M. A.; Guabiraba, R.; Bryant, C. E.; Ferguson, B. J.
10.1101/2020.10.01.321422 — immunology — Posted on 2020-10-02
4183 Autobiographical memory reactivation in empathy: EEG and fMRI evidence
Meconi, F.; Linde-Domingo, J.; Ferreira, C. S.; Michelmann, S.; Staresina, B.; Apperly, I. I.; Hanslmayr, S.
10.1101/715276 — neuroscience — Posted on 2020-10-01
4184 Arabidopsis ACINUS is O-glycosylated and regulates transcription and alternative splicing of regulators of reproductive transitions
Bi, Y.; Deng, Z.; Ni, W.; Shrestha, R.; Savage, D.; Hartwig, T.; Patil, S.; Hong, S. H.; Oses-Prieto, J. A.; Li, K. H.; Quail, P. H.; Burlingame, A.; xu, S.-L.; Wang, Z.-Y.
10.1101/2020.10.01.322347 — molecular biology — Posted on 2020-10-01
4185 GABA quantification in human anterior cingulate cortex
Weis, J.; Persson, J.; Frick, A.; Ahs, F.; Versluis, M.; Alamidi, D.
10.1101/2020.10.01.322008 — neuroscience — Posted on 2020-10-01
4189 Detection of differentially abundant cell subpopulations discriminates biological states in scRNA-seq data
Zhao, J.; Jaffe, A.; Li, H.; Lindenbaum, O.; Sefik, E.; Jackson, R.; Cheng, X.; Flavell, R.; Kluger, Y.
10.1101/711929 — bioinformatics — Posted on 2020-10-01
4190 On-site eDNA detection of species using ultra-rapid mobile PCR
Doi, H.; Watanabe, T.; Nishizawa, N.; Saito, T.; Nagata, H.; Kameda, Y.; Ikeda, K.; Maki, N.; Fukuzawa, T.
10.1101/2020.09.28.314625 — ecology — Posted on 2020-10-01
4193 Snx14 proximity labeling reveals a role in saturated fatty acid metabolism and ER homeostasis defective in SCAR20 disease
Datta, S.; Bowerman, J.; Hariri, H.; Ugrankar, R.; Eckert, K.; Corley, C.; Vale, G.; McDonald, J. G.; Henne, M. M.
10.1101/2020.05.31.126441 — cell biology — Posted on 2020-10-01
4194 Perilipin2 down-regulation in beta cells impairs insulin secretion under nutritional stress and damages mitochondria
Mishra, A.; Liu, S.; Promes, J.; Harata, M.; Sivitz, W.; Fink, B.; Bhardwaj, G.; O'Neill, B.; Kang, C.; Sah, R.; Strack, S.; Stephens, S.; King, T.; Jackson, L.; Greenberg, A.; Anokye-Danso, F.; Ahima, R.; Ankrum, J. A.; Imai, Y.
10.1101/2020.10.01.322974 — molecular biology — Posted on 2020-10-01
4195 Sequence- and structure-specific cytosine-5 mRNA methylation by NSUN6
Selmi, T.; Hussain, S.; Dietmann, S.; Heiss, M.; Carter, J.-M.; Dennison, R.; Flad, S.; Huang, Y.-L.; Kellner, S.; Borneloev, S.; Frye, M.
10.1101/2020.10.01.320036 — molecular biology — Posted on 2020-10-01
4196 Phenotypic Differences in Adult and Fetal Dermal Fibroblast Responses to Mechanical Tension
Parikh, U. M.; Short, W. D.; Templeman, N.; Blum, D.; Colchado, D.; Strang, H.; Kaul, A.; Li, H.; Wang, X.; Fahrenholtz, M. M.; Balaji, S.
10.1101/2020.09.30.319749 — molecular biology — Posted on 2020-10-01
4197 Ex vivo Immune Profiling in Patient Blood enables Quantification of innate immune Effector Functions
Lehnert, T.; Leonhardt, I.; Timme, S.; Thomas-Rüddel, D.; Bloos, F.; Sponholz, C.; Kurzai, O.; Figge, M. T.; Hünniger, K.
10.1101/2020.10.01.322032 — immunology — Posted on 2020-10-01
4198 The restricted nature of protein glycosylation in the mammalian brain
Williams, S. W.; Noel, M.; Lehoux, S. D.; Cetinbas, M.; Xavier, R. J.; Sadreyev, R.; Scolnick, E. M.; Smoller, J. W.; Cummings, R. D.; Mealer, R. G.
10.1101/2020.10.01.322537 — neuroscience — Posted on 2020-10-01
4199 Single cell transcriptional and functional analysis of human dopamine neurons in 3D fetal ventral midbrain organoid like cultures
Birtele, M.; Sharma, Y.; Storm, P.; Kajtez, J.; Sozzi, E.; Nilsson, F.; Nelander Wahlestedt, J.; Stott, S.; L He, X.; Mattsson, B.; Rylander Ottosson, D.; Barker, R. A.; Fiorenzano, A.; Parmar, M.
10.1101/2020.10.01.322495 — neuroscience — Posted on 2020-10-01
4201 Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice
Rydze, R. T.; Patton, B.; Torralba, H. S.; Briley, S.; Gipson, G.; James, R.; Rajkovic, A.; Thompson, T. B.; Pangas, S.
10.1101/2020.10.01.322818 — physiology — Posted on 2020-10-01
4211 Torsin ATPases influence chromatin interaction of the Torsin regulator LAP1
Luithle, N.; uit de Bos, J.; Hovius, R.; Maslennikova, D.; Lewis, R.; Ungricht, R.; Fierz, B.; Kutay, U.
10.1101/2020.10.01.321869 — cell biology — Posted on 2020-10-01
4212 Phages weaponize their bacteria with biosynthetic gene clusters
Dragos, A.; Andersen, A. J. C.; Lozano-Andrade, C. N.; Kempen, P. J.; Kovacs, A. T.; Lenz Strube, M.
10.1101/2020.10.01.322628 — microbiology — Posted on 2020-10-01
4214 Cytomegaloviral determinants of CD8+ T cell programming and RhCMV/SIV vaccine efficacy
Malouli, D.; Hansen, S. G.; Hancock, M. H.; Hughes, C. M.; Ford, J. C.; Gilbride, R. M.; Ventura, A. B.; Morrow, D.; Taher, H.; Uebelhoer, L. S.; McArdle, M. R.; Papen, C. R.; Espinosa Trethewy, R.; Oswald, K.; Shoemaker, R.; Berkemeier, B.; Bosche, W.; Hull, M.; Green, J.; Axthelm, M. K.; Shao, J.; Edlefsen, P.; Grey, F.; Nelson, J. A.; Lifson, J. D.; Streblow, D. N.; Sacha, J.; Früh, K.; Picker, L. J.
10.1101/2020.09.30.321349 — immunology — Posted on 2020-10-01
4215 Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing
HU, C.; CHU, C.; LIU, L.; jin, s.; yang, r.; rung, s.; li, j.; QU, Y.; MAN, Y.
10.1101/2020.08.10.243659 — immunology — Posted on 2020-10-01
4220 Aβinduces acute oxidative stress leading to brain glucose hypometabolism and hyperactivity in Alzheimer's disease pathogenesis
Malkov, A.; Popova, I.; Ivanov, A.; Jang, S.-S.; Yoon, S. Y.; Osipov, A.; Huang, Y.; Zilberter, Y.; Zilberter, M.
10.1101/2020.08.12.248492 — neuroscience — Posted on 2020-10-01
4221 Distinct higher-order representations of natural sounds in human and ferret auditory cortex
Landemard, A.; Bimbard, C.; Demene, C.; Shamma, S.; Norman-Haignere, S. V.; Boubenec, Y.
10.1101/2020.09.30.321695 — neuroscience — Posted on 2020-10-01
4222 Inhibiting the mitochondrial pyruvate carrier does not ameliorate synucleinopathy in the absence of inflammation or metabolic deficits
Peelaerts, W.; Bergkvist, L.; George, S.; Johnson, M. E.; Meyerdirk, l.; Kuhn, E.; Steiner, J.; Madaj, Z.; Ma, J.; Becker, K.; Nilsson, P. R.; Colca, J.; Brundin, P.
10.1101/2020.10.01.322115 — neuroscience — Posted on 2020-10-01
4223 Wiring diagram of the oxytocin system in the mouse brain
Son, S.; Manjila, S. B.; Newmaster, K. T.; Wu, Y.-t.; Vanselow, D. J.; Ciarletta, M.; Cheng, K. C.; Kim, Y.
10.1101/2020.10.01.320978 — neuroscience — Posted on 2020-10-01
4228 Multi Locus View: An Extensible Web Based Tool for the Analysis of Genomic Data
Sergeant, M.; Hughes, J. R.; Hentges, L.; Lunter, G.; Downes, D.; Taylor, S.
10.1101/2020.06.15.151837 — bioinformatics — Posted on 2020-10-01
4229 Scaffold pore geometry influences bone-like tissue formation in dynamic cell culture conditions
Rubert, M.; Vetsch, J. R.; Lehtoviita, I.; Sommer, M.; Zhao, F.; Studart, A. R.; Mueller, R.; Hofmann, S.
10.1101/2020.04.24.060525 — bioengineering — Posted on 2020-10-01
4231 Psychosocial experiences modulate asthma-associated genes through gene-environment interactions
Resztak, J. A.; Farrell, A. K.; Mair-Meijers, H.; Alazizi, A.; Wen, X.; Wildman, D. E.; Zilioli, S.; Slatcher, R. B.; Pique-Regi, R.; Luca, F.
10.1101/2020.07.16.206912 — genomics — Posted on 2020-10-01
4232 Altered oligodendroglia and astroglia in chronic traumatic encephalopathy
Chancellor, K. B.; Chancellor, S. E.; Duke-Cohan, J. E.; Huber, B. R.; Stein, T. D.; Alvarez, V. E.; Okaty, B. W.; Dymecki, S. M.; McKee, A. C.
10.1101/2020.05.13.089086 — genomics — Posted on 2020-10-01
4236 Changes in arthropod community but not plant quality benefit a specialist herbivore on plant under reduced water availability
Lin, P.-A.; Liu, C.-M.; Ou, J.-A.; Sun, C.-H.; Chuang, W.-P.; Ho, C.-K.; Kinoshita, N.; Felton, G. W.
10.1101/2020.05.25.115519 — ecology — Posted on 2020-10-01
4239 The Role of DOT1L Methyltransferase Activity in Fetal Hematopoiesis
Malcom, C. A.; Piaseka-Srader, J.; Chakravarthi, V. P.; Borosha, S.; Ratri, A.; Alvarez, N.; Vivian, J. L.; Fields, T. A.; Rumi, M. A.; Fields, P. E.
10.1101/2020.09.30.319889 — developmental biology — Posted on 2020-10-01
4241 Endogenous Galectin-3 is Required for Skeletal Muscle Repair
Cerri, D. G.; Rodrigues, L. C.; Alves, V. M.; Machado, J.; Bastos, V. A. F.; Kettelhut, I. d. C.; Alberici, L. C.; Stowell, S. R.; Costa, M. C. R.; Cummings, R. D.; Baruffi, M. D.
10.1101/2020.10.01.322461 — cell biology — Posted on 2020-10-01
4242 Opposing functions for retromer and Rab11 in extracellular vesicle cargo traffic at presynaptic terminals
Walsh, R. B.; Becalska, A. N.; Zunitch, M. J.; Lemos, T.; Dresselhaus, E. C.; Lee, S. M.; Wang, S.; Isaac, B.; Yeh, A.; Koles, K.; Rodal, A. A.
10.1101/645713 — cell biology — Posted on 2020-10-01
4246 Single Cell Analysis Reveals Multi-faceted miR-375 Regulation of the Intestinal Crypt
Shanahan, M. T.; Kanke, M.; Singh, A. P.; Villanueva, J. W.; McNairn, A. J.; Oyesola, O. O.; Bonfini, A.; Hung, Y.-H.; Sheahan, B.; Bloom, J. C.; Cubitt, R. L.; Curry, E. G.; Pitman, W. A.; Rinaldi, V. D.; Dekaney, C. M.; Ding, S.; Peck, B. C. E.; Schimenti, J. C.; Dow, L. E.; Buchon, N.; Tait-Wojno, E. D.; Sethupathy, P.
10.1101/2020.10.01.321612 — molecular biology — Posted on 2020-10-01
4247 The replicative amplification of MITEs and their impact on rice trait variability
Castanera, R.; Vendrell-Mir, P.; Bardil, A.; Carpentier, M. C.; Panaud, O.; Casacuberta, J.
10.1101/2020.10.01.322784 — molecular biology — Posted on 2020-10-01
4248 Megasphaera in the stool microbiota is negatively associated with diarrheal cryptosporidiosis
Carey, M. A.; Medlock, G. L.; Alam, M.; Kabir, M.; Uddin, M. J.; Nayak, U.; Papin, J. A.; Faruque, A. S. G.; Haque, R.; Petri, W. A.; Gilchrist, C. A.
10.1101/2020.10.01.323147 — microbiology — Posted on 2020-10-01
4250 Conserved human effector Treg signature is reflected in transcriptomic and epigenetic landscape
Mijnheer, G.; Lutter, L.; Mokry, M.; van der Wal, M.; Fleskens, V.; Scholman, R.; Pandit, A.; Tao, W.; Wekking, M.; Vervoort, S.; Roberts, C.; Petrelli, A.; Peeters, J.; Knijff, M.; de Roock, S.; Vastert, S.; Taams, L.; van Loosdregt, J.; van Wijk, F.
10.1101/2020.09.30.319962 — immunology — Posted on 2020-10-01
4251 GM-CSF differentiation of human monocytes stabilizes macrophage state via oxidative signaling
Itoh, C. Y.; Gunnarson, C.; Babunovic, G. H.; Nibasumba, A.; Akilimali, N. A.; Wadsworth, M. H.; Hughes, T. H.; Solomon, S. L.; Hie, B.; Berger, B.; Shalek, A. K.; Fortune, S. M.; Bryson, B. D.
10.1101/2020.09.29.318352 — immunology — Posted on 2020-10-01
4254 Shape-invariant perceptual encoding of dynamic facial expressions across species
Taubert, N.; Stettler, M.; Siebert, R.; Spadacenta, S.; Sting, L.; Dicke, P.; Thier, P.; Giese, M.
10.1101/2020.07.10.195941 — neuroscience — Posted on 2020-10-01
4255 Crowdsourcing neuroscience: inter-brain coupling during face-to-face interactions outside the laboratory
Dikker, S.; Michalareas, G.; Oostrik, M.; Serafimaki, A.; Kahraman, H. M.; Struiksma, M. E.; Poeppel, D.
10.1101/822320 — neuroscience — Posted on 2020-10-01
4259 Genome-wide association study reveals the genetic architecture of 27 yield-related traits in tomato
Ye, J.; Wang, X.; Wang, W.; Yu, H.; Ai, G.; Li, C.; Sun, P.; Wang, X.; Li, H.; Ouyang, B.; Zhang, J.; Zhang, Y.; Giovannoni, J.; Fei, Z.; Ye, Z.
10.1101/2020.10.01.322214 — plant biology — Posted on 2020-10-01
4261 The hepatic compensatory response to elevated systemic sulfide promotes diabetes
Carter, R. N.; Gibbins, M. T. G.; Barrios-Llerena, M. E.; Wilkie, S. E.; Freddolino, P. L.; Libiad, M.; Vitvitsky, V.; Emerson, B.; Le Bihan, T.; Brice, M.; Su, H.; Denham, S. G.; Homer, N. Z. M.; Mc Fadden, C.; Tailleux, A.; Faresse, N.; Sulpice, T.; Briand, F.; Gillingwater, T.; Ahn, K. H.; Singha, S.; McMaster, C.; Hartley, R. C.; Staels, B.; Gray, G. A.; Finch, A. J.; Selman, C.; Banerjee, R.; Morton, N. M.
10.1101/2020.04.27.064287 — physiology — Posted on 2020-10-01
4262 Development and Characterization of Patient-Derived Xenografts from Non-Small Cell Lung Cancer Brain Metastases
Baschnagel, A. M.; Kaushik, S.; Durmaz, A.; Goldstein, S.; Ong, I. M.; Abel, L.; Clark, P. A.; Leal, T.; Buehler, D.; Iyer, G.; Scott, J. G.; Kimple, R. J.
10.1101/2020.06.02.130062 — cancer biology — Posted on 2020-10-01
4265 OrganoidTracker: efficient cell tracking using machine learning and manual error correction
Kok, R. N. U.; Hebert, L.; Huelsz-Prince, G.; Goos, Y. J.; Zheng, X.; Bozek, K.; Stephens, G. J.; Tans, S. J.; van Zon, J. S.
10.1101/2020.03.18.996421 — bioinformatics — Posted on 2020-10-01
4266 Proteoglycan 4 (PRG4) expression and functionin dry eye associated inflammation
Menon, N. G.; Goyal, R.; Lema, C.; Woods, P.; Jay, G. D.; Shapiro, L. H.; Redfern, R. L.; Ghosh, M.; Schimdt, T. A.
10.1101/2020.10.01.318576 — biochemistry — Posted on 2020-10-01
4267 Harnessing Ionic Selectivity In Acetyltransferase Chemoproteomic Probes
Jing, Y.; Montano, J. L.; Levy, M. J.; Lopez, J.; Kung, P.-P.; Richardson, P.; Krajewski, K.; Florens, L.; Washburn, M.; Meier, J. L.
10.1101/2020.09.24.311530 — biochemistry — Posted on 2020-10-01
4270 Identification and characterization of key long non-coding RNAs in the mouse cochlea
Koffler-Brill, T.; Taiber, S.; Anaya, A.; Bordeynik-Cohen, M.; Rosen, E.; Kolla, L.; Messika-Gold, N.; Elkon, R.; Kelley, M. W.; Ulitsky, I.; Avraham, K. B.
10.1101/2020.07.10.197251 — genomics — Posted on 2020-10-01
4271 LDpred2: better, faster, stronger
Prive, F.; Arbel, J.; Vilhjalmsson, B. J.
10.1101/2020.04.28.066720 — genetics — Posted on 2020-10-01
4274 Epigenetic clock and DNA methylation analysis of porcine models of aging and obesity
Schachtschneider, K. M.; Schook, L. B.; Meudt, J. J.; Shanmuganayagam, D.; Zoller, J. A.; Haghani, A.; Li, C. Z.; Zhang, J.; Yang, A.; Raj, K.; Horvath, S.
10.1101/2020.09.29.319509 — developmental biology — Posted on 2020-10-01
4275 DDX3X and DDX3Y are redundant in protein synthesis
Venkataramanan, S.; Calviello, L.; Wilkins, K.; Floor, S. N.
10.1101/2020.09.30.319376 — molecular biology — Posted on 2020-10-01
4276 Bacterial glycocalyx integrity drives multicellular swarm biofilm dynamism
Saidi, F.; Jolivet, N. Y.; Lemon, D. J.; Nakamura, A.; Garza, A. G.; Veyrier, F. J.; Islam, S. T.
10.1101/2020.09.30.318626 — microbiology — Posted on 2020-10-01
4278 A conserved cell division protein directly regulates FtsZ dynamics in filamentous and unicellular actinobacteria
Schlimpert, S.; Ramos-Leon, F.; Bush, M. J.; McCormick, J. R.; Richardson, J.; Findlay, K.; Sallmen, J. W.
10.1101/2020.10.01.322578 — microbiology — Posted on 2020-10-01
4280 Novel taxa of Acidobacteriota involved in seafloor sulfur cycling
Flieder, M.; Buongiorno, J.; Herbold, C.; Hausmann, B.; Rattei, T.; Lloyd, K. G.; Loy, A.; Wasmund, K.
10.1101/2020.10.01.322446 — microbiology — Posted on 2020-10-01
4281 Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment
Pauken, K. E.; Shahid, O.; Lagattuta, K. A.; Mahuron, K. M.; Luber, J. M.; Lowe, M. M.; Huang, L.; Delaney, C.; Long, J. M.; Fung, M. E.; Newcomer, K.; Tsai, K. K.; Chow, M.; Guinn, S.; Kuchroo, J. R.; Burke, K. P.; Schenkel, J. M.; Rosenblum, M. D.; Daud, A. I.; Sharpe, A. H.; Singer, M.
10.1101/2020.09.30.294959 — immunology — Posted on 2020-10-01
4284 Epithelial HVEM promotes basement membrane synthesis and intraepithelial T cell survival and migration
Takahashi, D.; Wang, Q.; Seo, G.-Y.; Shui, J.-W.; Mikulski, Z.; Marcovecchio, P.; Takahashi, M.; Surh, C. D.; Cheroutre, H.; Kronenberg, M.
10.1101/2020.09.30.317628 — immunology — Posted on 2020-10-01
4285 Immunization by exposure to live virus (SIVmne/HIV-2287) during antiretroviral drug prophylaxis reduces risk of subsequent viral challenge
Frenkel, L. M.; Kuller, L.; Beck, I. A.; Tsai, C.-C.; Joy, J. P.; Mulvania, T. M.; Montefiori, D. C.; Anderson, D. M.
10.1101/2020.09.30.320820 — immunology — Posted on 2020-10-01
4289 The role of cation diffusion facilitator CDF-1 in lipid metabolism in Caenorhabditis elegans
Hu, Y.; Zhang, J.; Sheng, J.; Wang, Y.; Wang, X.; Wu, X.; Fu, L.; Liu, X.; Wen, Y.
10.1101/2020.09.30.320986 — zoology — Posted on 2020-10-01
4293 Bisphenol-S and Bisphenol-F alter mouse pancreatic β-cell ion channel expression and activity and insulin release through an estrogen receptor ERβ mediated pathway
Marroqui, L.; Martinez-Pinna, J.; Castellano-Munoz, M.; Dos Santos, R. S.; Medina-Gali, R. M.; Soriano, S.; Quesada, I.; Gustafsson, J.-A.; Encinar, J. A.; Nadal, A.
10.1101/2020.09.30.319988 — pharmacology and toxicology — Posted on 2020-10-01
4294 Enhanced Anticoagulation Activity of Functional RNA Origami
Krissanaprasit, A.; Key, C. M.; Froehlich, K.; Pontula, S.; Mihalko, E.; Dupont, D. M.; Andersen, E. S.; Kjems, J.; Brown, A. C.; LaBean, T. H.
10.1101/2020.09.29.319590 — bioengineering — Posted on 2020-10-01
4297 Leptin receptor expression in the dorsomedial hypothalamus stimulates breathing during NREM sleep in db/db mice
Pho, H.; Berger, S.; Freire, C.; Kim, L.; Shin, M.-k.; Streeter, S.; Hosamane, N.; Cabassa, M.; Anokye-Danso, F.; Dergacheva, O.; Amorim, M.; Fleury-Curado, T.; Jun, J.; Schwartz, A.; Ahima, R.; Mendelowitz, D.; Polotsky, V.
10.1101/2020.09.29.318758 — physiology — Posted on 2020-10-01
4299 Multiple early introductions of SARS-CoV-2 into a global travel hub in the Middle East
Abou Tayoun, A.; Loney, T.; Khansaheb, H.; Ramaswamy, S.; Harilal, D.; Deesi, Z.; Varghese, R.; Al Suwaidi, H.; Alkhajeh, A.; AlDabal, L.; Uddin, M.; Senok, A.; Hamoudi, R.; Halwani, R.; Hamid, Q.; Nowotny, N.; Alsheikh-Ali, A.
10.1101/2020.05.06.080606 — genomics — Posted on 2020-10-01
4300 Mutational landscape and in silico structure models of SARS-CoV-2 Spike Receptor Binding Domain reveal key molecular determinants for virus-host interaction
Nelson-Sathi, S.; Umasankar, P. K.; Easwaran, S.; Nair, R. R.; Joseph, I.; Nori, S. R. C.; Philip, J. S.; Prasad, R.; Navyasree, K. V.; Ramesh, S.; Pillai, H.; Gosh, S.; TR, S. K.; Pillai, M. R.
10.1101/2020.05.02.071811 — evolutionary biology — Posted on 2020-10-01
4304 Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T cell memory formation after mild COVID-19 infection
Minervina, A. A.; Komech, E. A.; Titov, A.; Bensouda Koraichi, M.; Rosati, E.; Mamedov, I. Z.; Franke, A.; Efimov, G. A.; Chudakov, D. M.; Mora, T.; Walczak, A. M.; Lebedev, Y. B.; Pogorelyy, M. V.
10.1101/2020.05.18.100545 — immunology — Posted on 2020-10-01
4306 ToxVec: Deep Language Model-Based Representation Learning for Venom Peptide Classification
Ahmadi, M.; Jahed-Motlagh, M. R.; Asgari, E.; Torkaman Rahmani, A.; McHardy, A. C.
10.1101/2020.09.29.319046 — bioinformatics — Posted on 2020-10-01
4307 A small interfering RNA (siRNA) database for SARS-CoV-2
Medeiros, I. G.; Khayat, A. S.; Stransky, B.; dos Santos, S. E. B.; Assumpcao, P. P.; de Souza, J. E. S.
10.1101/2020.09.30.321596 — bioinformatics — Posted on 2020-10-01
4309 Thiopurines activate an antiviral unfolded protein response that blocks viral glycoprotein accumulation in cell culture infection model
Slaine, P. D.; Kleer, M.; Duguay, B.; Pringle, E. S.; Kadijk, E.; Ying, S.; Balgi, A. D.; Roberge, M.; McCormick, C.; Khaperskyy, D. A.
10.1101/2020.09.30.319863 — microbiology — Posted on 2020-10-01
4310 SARS-CoV-2 viral budding and entry can be modeled using virus-like particles
Plescia, C. B.; David, E. A.; Patra, D.; Sengupta, R.; Amiar, S.; Su, Y.; Stahelin, R. V.
10.1101/2020.09.30.320903 — microbiology — Posted on 2020-10-01
4311 SARS-CoV-2 Spike protein promotes hyper-inflammatory response that can be ameliorated by Spike-antagonistic peptide and FDA-approved ER stress and MAP kinase inhibitors in vitro
Hsu, A. C.-Y.; Wang, G.; Reid, A. T.; Veerati, P. C.; Pathinayake, P. S.; Daly, K.; Mayall, J. R.; Hansbro, P. M.; Horvat, J. C.; Wang, F.; Wark, P. A.
10.1101/2020.09.30.317818 — immunology — Posted on 2020-10-01
4312 LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection
Jones, B. E.; Brown-Augsburger, P. L.; Corbett, K. S.; Westerndorf, K.; Davies, J.; Cujec, T. P.; Wiethoff, C. M.; Blackbourne, J. L.; Heinz, B. A.; Foster, D.; Higgs, R. E.; Balasubramaniam, D.; Wang, L.; Bidshahri, R.; Kraft, L.; Hwang, Y.; Zentelis, S.; Jepson, K. R.; Goya, R.; Smith, M. A.; Collins, D. W.; Hinshaw, S. J.; Tycho, S. A.; Pellacani, D.; Xiang, P.; Muthuraman, K.; Sobhanifar, S.; Piper, M. H.; Triana, F. J.; Hendle, J.; Pustilnik, A.; Adams, A. C.; Berens, S. J.; Baric, R. S.; Martinez, D. R.; Cross, R. W.; Geisbert, T. W.; Borisevich, V.; Abiona, O.; Belli, H. M.; de Vries, M
10.1101/2020.09.30.318972 — immunology — Posted on 2020-10-01
4313 Sexually divergent cortical control of affective-autonomic integration
Wallace, T.; Schaeuble, D.; Pace, S. A.; Schackmuth, M. K.; Hentges, S. T.; Chicco, A. J.; Myers, B.
10.1101/2020.09.29.319210 — neuroscience — Posted on 2020-10-01
4319 Evaluating spiny mice (Acomys) as a model for cardiac research
Shindo, K.; Peng, H.; Donahue, R. R.; Ahern, B. M.; Levitan, B. M.; Satin, J.; Seifert, A. W.; Abdel-Latif, A.
10.1101/2020.09.29.317388 — developmental biology — Posted on 2020-10-01
4320 Cardiac Sex Differences are Established Prior to Gonad Formation
Shi, W.; Sheng, X.; Dorr, K. M.; Hutton, J. E.; Davies, H. A.; Andrade, T. D.; Greco, T. M.; Hashimoto, Y.; Federspiel, J. D.; Robbe, Z. L.; Chen, X.; Arnold, A. P.; Ileana M Cristea, I. M.; Conlon, F.
10.1101/2020.09.29.319194 — developmental biology — Posted on 2020-10-01
4321 APEX2 proximity biotinylation reveals protein dynamics triggered by B cell receptor activation
Awoniyi, L. O.; Sustar, V.; Hernandez-Perez, S.; Vainio, M.; Sarapulov, A. V.; Petrov, P.; Mattila, P. K.
10.1101/2020.09.29.318766 — immunology — Posted on 2020-10-01
4325 Reversal of visual feedback modulates somatosensory plasticity
Goldenkoff, E. R.; McGregor, H. R.; Mergos, J.; Bridenstine, J.; Brown, M. J.; Vesia, M.
10.1101/2020.09.29.319350 — neuroscience — Posted on 2020-10-01
4326 QSM Reconstruction Challenge 2.0 Part 1: A Realistic in silico Head Phantom for MRI data simulation and evaluation of susceptibility mapping procedures
Marques, J. P.; Meineke, J.; Milovic, C.; Bilgic, B.; Chan, K.-S.; Hedouin, R.; vand der Zwaag, W.; Langkammer, C.; Schweser, F.
10.1101/2020.09.29.316836 — neuroscience — Posted on 2020-10-01
4333 Determination of Bacterial Surface Charge Density Via Saturation of Adsorbed Ions
Wilhelm, M. J.; Sharifian Gh., M.; Chang, C.-M.; Wu, T.; Li, Y.; Ma, J.; Dai, H.-L.
10.1101/2020.09.29.318840 — biophysics — Posted on 2020-10-01
4338 The Nature of Espeletia Species
Pineda, Y. M.; Cortes, A. J.; Madrinan, S.; Jimenez, I.
10.1101/2020.09.29.318865 — evolutionary biology — Posted on 2020-10-01
4344 A high fat anti-inflammatory diet improves widespread allodynia despite worsening metabolic outcomes in adult mice exposed to neonatal maternal separation
Eller, O. C.; Foright, R. M.; Brake, A. D.; Winter, M. K.; Bantis, L. E.; Morris, E. M. M.; Thyfault, J. P.; Christianson, J. A.
10.1101/2020.09.29.317297 — physiology — Posted on 2020-10-01
4346 The Role of DOT1L Methyltransferase Activity in Fetal Hematopoiesis
Malcom, C. A.; Piaseka-Srader, J.; Chakravarthi, V. P.; Borosha, S.; Ratri, A.; Alvarez, N.; Vivian, J. L.; Fields, T. A.; Rumi, M. A.; Fields, P. E.
10.1101/2020.09.30.319889 — developmental biology — Posted on 2020-10-01
4348 GNS561, a clinical-stage PPT1 inhibitor, has powerful antitumor activity against hepatocellular carcinoma via modulation of lysosomal functions
BRUN, S.; Raymond, E.; Bassissi, F.; Jilkova, Z. M.; Mezouar, S.; Rachid, M.; Novello, M.; Tracz, J.; Hamai, A.; Lalmanach, G.; Vanderlynden, L.; Bestion, E.; Legouffe, R.; Stauber, J.; Schubert, T.; Plach, M. G.; Courcambeck, J.; Drouot, C.; Jacquemot, G.; Serdjebi, C.; Roth, G.; Baudoin, J.-P.; Ansaldi, C.; Decaens, T.; Halfon, P.
10.1101/2020.09.30.320010 — cancer biology — Posted on 2020-10-01
4352 Brazilin Removes Toxic alpha-Synuclein and Seeding Competent Assemblies from Parkinson Brain by Altering Conformational Equilibrium
Nahass, G. R.; Sun, Y.; Xu, Y.; Batchelor, M.; Reilly, M.; Benilova, I.; Kedia, N.; Spehar, K.; Sobott, F.; Sessions, R. B.; Caughey, B.; Radford, S. E.; Jat, P.; Collinge, J.; Bieschke, J.
10.1101/2020.09.29.318220 — biochemistry — Posted on 2020-10-01
4354 Lipid-bound ApoE3 self-assemble into elliptical disc-shaped particles
Larsen, A. H.; Johansen, N. T.; Gajhede, M.; Arleth, L.; Midtgaard, S. R.
10.1101/2020.09.30.319905 — biochemistry — Posted on 2020-10-01
4355 Epistasis on the stability landscape of de novo TIM barrels explored by a modular design approach
Romero-Romero, S.; Costas, M.; Silva, D.-A.; Kordes, S.; Rojas-Ortega, E.; Guerra, Y.; Tapia, C.; Shanmugaratnam, S.; Rodriguez-Romero, A.; Baker, D.; Höcker, B.; Fernandez-Velasco, D. A.
10.1101/2020.09.29.319103 — biochemistry — Posted on 2020-10-01
4356 TransMPRA: A framework for assaying the role of many trans-acting factors at many enhancers
Calderon, D.; Ellis, A.; Daza, R.; Martin, B.; Tome, J.; Chen, W.; Chardon, F.; Leith, A.; Lee, C.; Martin, B.; Trapnell, C.; Shendure, J.
10.1101/2020.09.30.321323 — genomics — Posted on 2020-10-01
4358 Characterization and analysis of the transcriptome in Arapaima gigas using multi-tissue RNA-sequencing
Martins, D. L.; Campos, L. R. S.; Ribeiro-dos-Santos, A. M.; Coelho, A. C. M. F.; Cavalcante, R.; Sobrinho, P. A. A.; Sakamoto, T.; Vidal, A. F.; Vinasco-Sandoval, G. T.; Assumpcao, P. P.; Santos, A. K. C. R.; Dalmolin, R. J. S.; de Souza, S. J.; dos Santos, S. E. B.; De Souza, J. E. S.
10.1101/2020.09.29.317222 — genomics — Posted on 2020-10-01
4360 Polyamines Mediate Folding of Primordial Hyper-Acidic Helical Proteins
Despotovic, D.; Longo, L. M.; Aharon, E.; Kahana, A.; Scherf, T.; Gruic-Sovulj, I.; Tawfik, D. S.
10.1101/2020.10.01.321877 — evolutionary biology — Posted on 2020-10-01
4363 Accessing mitochondrial protein import in living cells by protein microinjection
Bogorodskiy, A.; Okhrimenko, I.; Maslov, I.; Maliar, N.; Burkatovskiy, D.; von Ameln, F.; Schulga, A.; Jakobs, P.; Altschmied, J.; Haendeler, J.; Katranidis, A.; Mishin, A.; Gordeliy, V.; Bueldt, G.; Voos, W.; Gensch, T.; Borshchevskiy, V.
10.1101/2020.09.30.317412 — cell biology — Posted on 2020-10-01
4365 Early growth response 2 (EGR2) is a novel regulator of the senescence program
Tyler, E. J.; Gutierrez Del Arroyo, A.; Wallis, R.; Hughes, B. K.; Garbe, J. C.; Stampfer, M. R.; Koh, J.; Lowe, R.; Philpott, M. P.; Bishop, C. L.
10.1101/2020.09.30.321190 — cell biology — Posted on 2020-10-01
4369 GM-CSF differentiation of human monocytes stabilizes macrophage state via oxidative signaling
Bryson, B. D.; Itoh, C. Y.; Gunnarson, C.; Babunovic, G. H.; Nibasumba, A.; Akilimali, N. A.; Wadsworth, M. H.; Hughes, T. H.; Solomon, S. L.; Hie, B.; Berger, B.; Shalek, A. K.; Fortune, S. M.
10.1101/2020.09.29.318352 — immunology — Posted on 2020-10-01
4371 New insights into large tropical tree mass and structure from direct harvest and terrestrial lidar
Burt, A.; Boni Vicari, M.; da Costa, A. C. L.; Coughlin, I.; Meir, P.; Rowland, L.; Disney, M.
10.1101/2020.09.29.317198 — ecology — Posted on 2020-10-01
4374 Architecture of the Tuberous Sclerosis Protein Complex
Ramlaul, K.; Fu, W.; Li, H.; de Martin Garrido, N.; He, L.; Cui, W.; Aylett, C. H. S.; Wu, G.
10.1101/2020.09.29.319707 — cell biology — Posted on 2020-10-01
4375 Mitochondria fragment and reassemble to initiate the formation and development of the nucleus
Hou, B.; Xu, Y.; Li, E.; Cao, P.; Liu, S.; Xi, Z.; Yang, H.; Huo, Y.; Che, Y.; Jiang, X.
10.1101/2020.09.29.319723 — cell biology — Posted on 2020-10-01
4376 REEP4 is recruited to the inner nuclear membrane by ELYS and promotes nuclear pore complex formation
Golchoubian, B.; Brunner, A.; Bragulat-Teixidor, H.; Akarlar, B. A.; Ozlu, N.; Schlaitz, A.-L.
10.1101/2020.09.30.320333 — cell biology — Posted on 2020-10-01
4379 Reproductive resilience but not root architecture underpin yield improvement in maize
Messina, C.; Cooper, M.; McDonald, D.; Poffenbarger, H.; Clark, R.; Salinas, A.; Fang, Y.; Gho, C.; Tang, T.; Graham, G.
10.1101/2020.09.30.320937 — plant biology — Posted on 2020-10-01
4381 An improved experimental pipeline for preparing circular ssDNA viruses for next-generation sequencing
Aimone, C. D.; Hoyer, J. S.; Dye, A. E.; Deppong, D. O.; Duffy, S.; Carbone, I.; Hanley-Bowdoin, L.
10.1101/2020.09.30.321224 — plant biology — Posted on 2020-10-01
4385 Dynamics of brain function in chronic pain patients assessed by microstate analysis of resting-state electroencephalography
May, E.; Gil Avila, C.; Ta Dinh, S.; Heitmann, H.; Hohn, V.; Nickel, M.; Tiemann, L.; Toelle, T.; Ploner, M.
10.1101/2020.09.29.318246 — neuroscience — Posted on 2020-10-01
4389 Modeling multifunctionality of genes with secondary gene co-expression networks in human brain provides novel disease insights
Sanchez, J. A.; Gil-Martinez, A. L.; Cisterna, A.; Garcia-Ruiz, S.; Gomez, A.; Reynolds, R. H.; Nalls, M. A.; Hardy, J.; Ryten, M.; Botia, J. A.
10.1101/2020.09.29.317305 — bioinformatics — Posted on 2020-10-01
4390 Robust and independent metabolic transcriptional components in 34,494 patient-derived samples and cell lines: a resource for translational cancer research
Leeuwenburgh, V. C.; Urzua-Traslavina, C. G.; Bhattacharya, A.; Walvoort, M. T. C.; Jalving, M.; de Jong, S.; Fehrmann, R. S. N.
10.1101/2020.10.01.321950 — bioinformatics — Posted on 2020-10-01
4391 RNAi gene knockdown in the poultry red mite, Dermanyssus gallinae (De Geer 1778), a tool for functional genomics
Chen, W.; Bartley, K.; Nunn, F.; Bowman, A. S.; Sternberg, J. M.; Burgess, S.; Nisbet, A. J.; Price, D. R. G.
10.1101/2020.09.28.316380 — genomics — Posted on 2020-10-01
4395 Within-species floral odor variation is maintained by spatial and temporal heterogeneity in pollinator communities
Szenteczki, M. A.; Godschalx, A. L.; Galman, A.; Espindola, A.; Gibernau, M.; Alvarez, N.; Rasmann, S.
10.1101/2020.09.29.318089 — ecology — Posted on 2020-10-01
4400 Brain Connectivity and Behavioral Changes in aSpaceflight Analog Environment with Elevated CO2
McGregor, H. R.; Lee, J.; Mulder, E.; De Dios, Y. E.; Beltran, N. E.; Kopfman, I.; Bloomberg, J. J.; Mulavara, A. P.; Seidler, R.
10.1101/2020.09.28.317404 — neuroscience — Posted on 2020-10-01
4404 Combining epiGBS markers with long read transcriptome sequencing to assess differentiation associated with habitat in Reynoutria (aka Fallopia)
Robertson, M. H.; Alvarez, M. F.; van Gurp, T. P.; Wagemaker, N. C. A. M.; Yu, F.; Moraga Amador, D.; Farmerie, W. G.; Verhoeven, K.; Richards, C. L.
10.1101/2020.09.30.317966 — plant biology — Posted on 2020-10-01
4405 PYL8 ABA receptors of Phoenix dactylifera play a crucial role in response to abiotic stress and are stabilized by ABA
Garcia-Maquilon, I.; Coego, A.; Lozano-Juste, J.; Messere, M.; de Ollas, C.; Julian, J.; Ruiz-Partida, R.; Pizzio, G.; Belda-Palazon, B.; Gomez-Cadenas, A.; Mayer, K. F.; Geiger, D.; Alquraish, S. A.; Alrefae, A. F.; Ache, P.; Hedrich, R.; Rodriguez, P. L.
10.1101/2020.09.29.318170 — plant biology — Posted on 2020-10-01
4407 Expression of a human cDNA in moss results in spliced mRNAs and fragmentary protein isoforms
Top, O.; Milferstaedt, S. W. L.; van Gessel, N.; Hoernstein, S. N. W.; Oezdemir, B.; Decker, E. L.; Reski, R.
10.1101/2020.09.30.320721 — plant biology — Posted on 2020-10-01
4408 Social Network Analysis of the Genealogy of Strawberry: Retracing the Wild Roots of Heirloom and Modern Cultivars
Pincot, D. D. A.; Ledda, M.; Feldmann, M.; Hardigan, M. A.; Poorten, T. J.; Runcie, D.; Heffelfinger, C.; Dellaporta, S. L.; Cole, G. S.; Knapp, S. J.
10.1101/2020.09.30.320689 — plant biology — Posted on 2020-10-01
4409 Momilactone B inhibits Arabidopsis growth and development via disruption of ABA and auxin signaling
Wu, J.; Long, J.; Lin, X.; Chang, Z.; Baerson, S. R.; Ding, C.; Wu, X.; Pan, Z.; Song, Y.; Zeng, R.
10.1101/2020.09.30.320655 — plant biology — Posted on 2020-10-01
4410 DET1-mediated COP1 regulation avoids HY5 activity over second-site targets to tune plant photomorphogenesis
Canibano, E.; Bourbousse, C.; Garcia-Leon, M.; Wolff, L.; Garcia-Baudino, C.; Barneche, F.; Rubio, V.; Fonseca, S.
10.1101/2020.09.30.318253 — plant biology — Posted on 2020-10-01
4413 The DNA methylation landscape of multiple myeloma shows extensive inter- and intrapatient heterogeneity that fuels transcriptomic variability
Derrien, J.; Guerin-Charbonnel, C.; Gaborit, V.; Campion, L.; Devic, M.; Douillard, E.; Roi, N.; Avet-Loiseau, H.; Decaux, O.; Facon, T.; Mallm, J.-P.; Eils, R.; Munshi, N. C.; Moreau, P.; Herrmann, C.; Magrangeas, F.; Minvielle, S.
10.1101/2020.10.01.321943 — cancer biology — Posted on 2020-10-01
4415 Regulation of kinase activity by combined action of juxtamembrane and C-terminal regions of receptors
Lin, C.-C.; Wieteska, L.; Poncet-Montange, G.; Suen, K. M.; Arold, S. T.; ahmed, z.; Ladbury, J. E.
10.1101/2020.10.01.322123 — biochemistry — Posted on 2020-10-01
4416 Making sense of the linear genome, gene function and TADs
Long, H. S.; Powell, G.; Greenaway, S.; Mallon, A.-M.; Lindgren, C. M.; Simon, M. M.
10.1101/2020.09.28.316786 — genomics — Posted on 2020-10-01
4418 Cellular Protrusions Engage Viral Infection Enhancing EF-C Peptide Nanofibrils
Schuetz, D.; Rode, S.; Read, C.; Mueller, J.; Glocker, B.; Sparrer, K. M.; Fackler, O.; Walther, P.; Muench, J.
10.1101/2020.10.01.321810 — cell biology — Posted on 2020-10-01
4420 LncRNAs interacting with the translation machinery contribute to human neuronal differentiation.
Douka, K.; Birds, I.; Wang, D.; Clayton, S.; Byford, A.; Vasconcelos, E. J. R.; O'Connell, M. J.; Deuchars, J.; Whitehouse, A.; Aspden, J. L.
10.1101/2020.10.01.321919 — molecular biology — Posted on 2020-10-01
4423 Hierarchical integration across multiple timescales in human auditory cortex
Norman-Haignere, S. V.; Long, L. K.; Devinsky, O.; Doyle, W.; Irobunda, I.; Merricks, E.; Feldstein, N. A.; McKhann, G. M. V.; Schevon, C.; Flinker, A.; Mesgarani, N.
10.1101/2020.09.30.321687 — neuroscience — Posted on 2020-10-01