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Archive, 2023-05

2 ChromaX: a fast and scalable breeding program simulator
Younis, O. G.; Turchetta, M.; Ariza Suarez, D.; Yates, S.; Studer, B.; Athanasiadis, I. N.; Krause, A.; Buhmann, J. M.; Corinzia, L.
10.1101/2023.05.29.542709 — bioinformatics — Posted on 2023-05-31
6 The slow evolving genome of the xenacoelomorph worm Xenoturbella bocki
Schiffer, P. H.; Natsidis, P.; Leite, D. J.; Robertson, H.; Lapraz, F.; Marletaz, F.; Fromm, B.; Baudry, L.; Simpson, F.; Hoye, E.; Zakrzewski, A.-C.; Kapli, P.; Hoff, K. J.; Mueller, S.; Marbouty, M.; Marlow, H.; Copley, R. H.; Koszul, R.; Sarkies, P.; Telford, M. J.
10.1101/2022.06.24.497508 — evolutionary biology — Posted on 2023-05-31
7 Common evolutionary origins of the bacterial glycyl tRNA synthetase and alanyl tRNA synthetase
Alvarez-Carreno, C.; Arciniega, M.; Ribas de Pouplana, L.; Petrov, A. S.; Hernandez-Gonzalez, A.; Valencia-Sanchez, M. I.; Williams, L. D.; Torres-Larios, A.
10.1101/2023.05.29.542759 — evolutionary biology — Posted on 2023-05-31
9 Heterogeneous genomic architecture of skeletal armour traits in sticklebacks
Yi, X.; Kemppainen, P.; Reid, K.; Chen, Y.; Rastas, P.; Fraimout, A.; Merilae, J.
10.1101/2023.05.28.542672 — evolutionary biology — Posted on 2023-05-31
14 Overcoming donor variability and risks associated with fecal microbiota transplants through bacteriophage-mediated treatments
Rasmussen, T. S.; Forster, S.; Larsen, S. B.; von Munchow, A.; Tranaes, K. D.; Brunse, A.; Castro-Mejia, J. L.; Adamberg, S.; Hansen, A. K.; Adamberg, K.; Hansen, C. H. F.; Nielsen, D. S.
10.1101/2023.03.17.532897 — microbiology — Posted on 2023-05-31
16 Cellular contributions to ictal population signals
Lau, L. A.; Zhao, Z.; Gomperts, S. N.; Staley, K. J.; Lillis, K. P.
10.1101/2022.07.08.499193 — neuroscience — Posted on 2023-05-31
20 Lyssa excreta: Defining parameters for fecal samples as a rabies virus surveillance method
Walker, F. M.; Upton, J. R.; Erickson, D.; Barrand, Z. A.; Brock, B.; Valentine, M.; Federman, E. L.; Froehlich, E. M.; Van Pelt, L. I.; Hastings, L.; Bergman, D. L.; Engelthaler, D. M.; Hepp, C. M.
10.1101/2023.05.27.542586 — pathology — Posted on 2023-05-31
24 High Throughput Single Cell Proteomic Analysis of Organ Derived Heterogeneous Cell Populations by Nanoflow Dual Trap Single Column Liquid Chromatography
Kreimer, S.; Binek, A.; Chazarin, B.; Cho, J. H.; Haghani, A.; Hutton, A.; Marban, E.; Mastali, M.; Meyer, J. G.; Mesquita, T.; Song, Y.; Van Eyk, J.; Parker, S. J.
10.1101/2023.01.06.522908 — biochemistry — Posted on 2023-05-31
25 Arpin deficiency increases actomyosin contractility and vascular permeability
Montoya-Garcia, A.; Guerrero-Fonseca, I. M.; Chanez-Paredes, S. D.; Hernandez-Almaraz, K. B.; Leon-Vega, I. I.; Silva-Olivares, A.; Betanzos, A.; Mondragon-Castelan, M.; Mondragon-Flores, R.; Salinas-Lara, C.; Vargas-Robles, H.; Schnoor, M.
10.1101/2023.05.29.542762 — cell biology — Posted on 2023-05-31
28 Genetic validation of PfFKBP35 as an antimalarial drug target
Thommen, B. T.; Dziekan, J. M.; Achcar, F.; Tjia, S.; Passecker, A.; Buczak, K.; Gumpp, C.; Schmidt, A.; Rottmann, M.; Gruering, C.; Marti, M.; Bozdech, Z.; Brancucci, N. M. B.
10.1101/2022.12.09.519720 — molecular biology — Posted on 2023-05-31
29 THE PALISADE LAYER OF THE POXVIRUS CORE IS COMPOSED OF FLEXIBLE A10-TRIMERS
Liu, J.; Corroyer-Dulmont, S.; Prazak, V.; Khusainov, I.; Bahrami, K.; Welsch, S.; Vasishtan, D.; Obarska-Kosinska, A.; Thorkelsson, S. R.; Grünewald, K.; Quemin, E. R. J.; Turonova, B.; Krijnse Locker, J.
10.1101/2023.05.24.542031 — molecular biology — Posted on 2023-05-31
31 Assessment of infant outgrowth of cow's milk allergy in relation to the faecal microbiome and metaproteome
Hendrickx, D. M.; An, R.; Boeren, S.; Mutte, S. K.; PRESTO study team, ; Lambert, J. M.; Belzer, C.
10.1101/2022.11.03.514997 — microbiology — Posted on 2023-05-31
33 Somatostatin peptide signaling dampens cortical circuits and promotes exploratory behavior
Brockway, D. F.; Griffith, K. R.; Aloimonos, C. M.; Clarity, T.; Moyer, J. B.; Smith, G. C.; Dao, N. C.; Hossain, M. S.; Drew, P. J.; Gordon, J. A.; Kupferschmidt, D. A.; Crowley, N. A.
10.1101/2022.07.18.499817 — neuroscience — Posted on 2023-05-31
34 Low-dose carbon monoxide is neuroprotective in rodent models of Parkinson's disease
Rose, K. N.; Zorlu, M.; Xue, X.; Cai, W.; Lin, S.; Schwarzschild, M.; Chen, X.; Gomperts, S. N.
10.1101/2023.05.27.542565 — neuroscience — Posted on 2023-05-31
35 Mapping the Organization and Morphology of Calcitonin Gene-Related Peptide (CGRP)-IR Axons in the Whole Mouse Stomach
Ma, J.; Nguyen, D.; Madas, J.; Bizanti, A.; Mistareehi, A.; Kwiat, A. M.; Chen, J.; Lin, M.; Christie, R.; Hunter, P.; Heal, M.; Baldwin, S.; Tappan, S.; Furness, J. B.; Powley, T. L.; Cheng, Z. J.
10.1101/2023.05.23.541811 — neuroscience — Posted on 2023-05-31
38 Representation and quantification Of Module Activity from omics data with rROMA
Najm, M.; Cornet, M.; Albergante, L.; Zinovyev, A.; Sermet-Gaudelus, I.; Stoven, V.; Calzone, L.; MARTIGNETTI, L.
10.1101/2022.10.24.513448 — systems biology — Posted on 2023-05-31
41 Microwell-enhanced optical rapid antibiotic susceptibility testing of single bacteria
Roslon, I.; Japaridze, A.; Rodenhuis, S.; Hamoen, L.; Ghatkesar, M.; Steeneken, P.; Dekker, C.; Alijani, F.
10.1101/2023.02.20.529233 — bioengineering — Posted on 2023-05-31
43 The oncogene cyclin D1 promotes bipolar spindle integrity under compressive force
Sutanto, R.; Neahring, L.; Marques, A. S.; Kilinc, S.; Goga, A.; Dumont, S.
10.1101/2023.05.30.542893 — cell biology — Posted on 2023-05-31
46 Purinergic P2Y2 Receptor-Induced Activation of Endothelial TRPV4 Channels Mediates Lung Ischemia-Reperfusion Injury
Kuppusamy, M.; Ta, H. Q.; Davenport, H. N.; Bazaz, A.; Kulshrestha, A.; Daneva, Z.; Chen, Y.-L.; Carrott, P. W.; Laubach, V. E.; Sonkusare, S. K.
10.1101/2023.05.29.542520 — physiology — Posted on 2023-05-31
51 EWS::FLI1-DHX9 interaction promotes Ewing sarcoma sensitivity to DNA topoisomerase 1 poisons by altering R-loop metabolism
Olmedo-Pelayo, J.; Granado-Calle, E. L.; Delgado-Bellido, D.; Lobo-Selma, L.; Jordan-Perez, C.; Monteiro-Amaral, A. T.; Ehlers, A. C.; Ohmura, S.; Carcaboso, A. M.; Alonso, J.; Machado, I.; Llombart-Bosch, A.; Grunewald, T. G. P.; Gomez-Herreros, F.; de Alava, E.
10.1101/2023.05.30.542894 — cancer biology — Posted on 2023-05-31
52 Transcription Factor EB (TFEB) activity increases resistance of TNBC stem cells to metabolic stress
Van Den Berg, C. L.; Soleimani, M.; Goyal, R.; Somma, A.; Kaoud, T.; Dalby, K. N.; Kowalski, J.; Eckhardt, S. G.
10.1101/2023.05.30.542913 — cancer biology — Posted on 2023-05-31
53 The Nbeta motif of NaTrxh directs secretion as an endoplasmic reticulum transit peptide and variations might result in different cellular targeting
Juarez-Diaz, J. A.; Zaragoza-Gomez, A.; Garcia-Caffarel, E.; Cruz-Zamora, Y.; Gonzalez, J.; Anaya-Munoz, V. H.; Cruz-Garcia, F.
10.1101/2023.05.31.543037 — cell biology — Posted on 2023-05-31
56 A new vulnerability to BET inhibition due to enhanced autophagy in BRCA2 deficient pancreatic cancer
Lee, E.; Archasappawat, S.; Ji, K.; Pena, J.; Fernandez-Vega, V.; Gangaraju, R.; Beesabathuni, N. S.; Kim, M.; Tian, Q.; Shah, P.; Scampavia, L.; Spicer, T.; Hwang, C.-i.
10.1101/2023.05.30.542934 — cancer biology — Posted on 2023-05-31
58 Rescue of secretion of a rare-disease associated mis-folded mutant glycoprotein in UGGT1 knock-out mammalian cells
Tax, G.; Guay, K. P.; Solde, T.; Hitchman, C. J.; Hill, J. C.; Vasilievic, S.; Lia, A.; Modenutti, C. P.; Straatman, K. R.; Molinari, M.; Santino, A.; Hebert, D. N.; Zitzmann, N.; Roversi, P.; Trerotola, M.
10.1101/2023.05.30.542711 — cell biology — Posted on 2023-05-31
60 Essential role of the Conserved Oligomeric Golgi complex in Toxoplasma gondii
Marsilia, C.; Batra, M.; Pokrovskaya, I. D.; Wang, C.; Chaput, D.; Naumova, D. A.; Lupashin, V. V.; Suvorova, E. S.
10.1101/2023.05.30.542952 — cell biology — Posted on 2023-05-31
62 Human plasma-like medium facilitates metabolic tracing and enables upregulation of immune signaling pathways in glioblastoma explants
El Shami, M.; Savani, M. R.; Gattie, L. C.; Smith, B.; Hicks, W. H.; Rich, J. N.; Richardson, T. E.; McBrayer, S. K.; Abdullah, K. G.
10.1101/2023.05.29.542774 — cancer biology — Posted on 2023-05-31
63 Structural basis of substrate progression through the chaperonin cycle
Gardner, S.; Darrow, M. C.; Lukoyanova, N.; Thalassinos, K.; Saibil, H. R.
10.1101/2023.05.29.542693 — biophysics — Posted on 2023-05-31
64 Illuminating Dark Chemical Matter using the Cell Painting Assay
Pahl, A.; Liu, J.; Patil, S.; Rezaei Adariani, S.; Scholermann, B.; Bonowski, J.; Koska, S.; Sievers, S.; Warmers, J.; Ziegler, S.; Waldmann, H.
10.1101/2023.05.31.542818 — cell biology — Posted on 2023-05-31
65 Unique interactions and functions of the mitochondrial small Tims in Trypanosoma brucei
Quinones Guillen, L. S.; Gonzalez, F. S.; Darden, C.; Khan, M.; Tripathi, A.; Smith, J.; Cooley, A.; Paromov, V.; Davis, J.; Misra, S.; Chaudhuri, M.
10.1101/2023.05.29.542777 — cell biology — Posted on 2023-05-31
66 Recalibration of protein interactions in Martini 3
Thomasen, F. E.; Skaalum, T.; Kumar, A.; Srinivasan, S.; Vanni, S.; Lindorff-Larsen, K.
10.1101/2023.05.29.542689 — biophysics — Posted on 2023-05-31
67 Lipid Bilayer Strengthens the Cooperative Network of a Membrane-Integral Enzyme
Muhammednazaar, S.; Yao, J.; Guo, R.; Rhee, M. S.; Kim, K. H.; Kang, S.-g.; Hong, H.
10.1101/2023.05.30.542905 — biophysics — Posted on 2023-05-31
68 Bioluminescence imaging of Cyp1a1-luciferase reporter mice demonstrates prolonged activation of the aryl hydrocarbon receptor in the lung
Veland, N.; Gleneadie, H. J.; Brown, K. E.; Sardini, A.; Pombo, J.; Dimond, A.; Burns, V.; Sarkisyan, K.; Schiering, C.; Webster, Z.; Merkenschlager, M.; Fisher, A. G.
10.1101/2023.05.30.542862 — cell biology — Posted on 2023-05-31
76 Quantitative Determination of Protein Concentration in Living Cells
Brinkenfeldt, N.; Dias, A.; Moreno-Pescador, G.; Bendix, P. M.; Martinez, K. L.
10.1101/2023.05.31.542874 — biophysics — Posted on 2023-05-31
77 Particle-based phasor-FLIM-FRET resolves protein-protein interactions inside single viral particles
Coucke, Q.; Parveen, N.; Fernandez, G. S.; Qian, C.; Hofkens, J.; Debyser, Z.; Hendrix, J.
10.1101/2023.05.31.543036 — biophysics — Posted on 2023-05-31
78 Denaturing mass photometry for straightforward optimization of protein-protein cross-linking reactions at single-molecule level
Gizardin-Fredon, H.; Santo, P. E.; Chagot, M.-E.; Charpentier, B.; Bandeiras, T. M.; Manival, X.; Hernandez-Alba, O.; Cianferani, S.
10.1101/2023.05.30.542861 — biophysics — Posted on 2023-05-31
82 Are fungi capacitors?
Szacilowski, K.; Beasley, A. E.; Mech, K.; Adamatzky, A.
10.1101/2023.05.28.542674 — biophysics — Posted on 2023-05-31
85 Epigenetics Insights from Perceived Facial Aging
Vladimir, K.; Perisic, M. M.; Storga, M.; Mostashari, A.; Khanin, R.
10.1101/2023.05.29.542727 — genomics — Posted on 2023-05-31
86 A Spatiotemporal Notch Interaction Map from Membrane to Nucleus
Martin, A. P.; Bradshaw, G. A.; Eisert, R. J.; Egan, E. D.; Tveriakhina, L.; Rogers, J. M.; Dates, A. N.; Scanavachi, G.; Aster, J. C.; Kirchhausen, T.; Kalocsay, M.; Blacklow, S. C.
10.1101/2022.12.21.521435 — molecular biology — Posted on 2023-05-30
87 Rapid cloning-free mutagenesis of new SARS-CoV-2 variants using a novel reverse genetics platform
Kipfer, E. T.; Hauser, D.; Lett, M. J.; Otte, F.; Urda, L.; Zhang, Y.; Lang, C. M. R.; Chami, M.; Mittelholzer, C.; Klimkait, T.
10.1101/2023.05.11.540343 — molecular biology — Posted on 2023-05-30
91 Large Scale Foundation Model on Single-cell Transcriptomics
Hao, M.; Gong, J.; Zeng, X.; Liu, C.; Guo, Y.; Cheng, X.; Wang, T.; Ma, J.; Song, L.; Zhang, X.
10.1101/2023.05.29.542705 — bioinformatics — Posted on 2023-05-31
94 Deciphering deep-sea chemosynthetic symbiosis by single-nucleus RNA-sequencing
Wang, H.; He, K.; Zhang, H.; Zhang, Q.; Cao, L.; Li, J.; Zhong, Z.; Chen, H.; Zhou, L.; Lian, C.; Wang, M.; Chen, K.; Qian, P.-Y.; Li, C.
10.1101/2023.05.29.542712 — ecology — Posted on 2023-05-31
95 Isolation of Biologically Active Extracellular Vesicles-Associated AAVs for Gene Delivery to the Brain by Size Exclusion Chromatography
Henriques, C.; Lopes, M. M.; Albuquerque, P.; Rufino-Ramos, D.; Gaspar, L. S.; Lobo, D.; Leandro, K.; Silva, A. C.; Baganha, R.; Duarte, S.; Maguire, C. A.; Santana, M.; Pereira de Almeida, L.; Nobre, R. J.
10.1101/2023.05.30.542901 — molecular biology — Posted on 2023-05-30
96 Wnt binding to Coatomer proteins directs secretion on exosomes independently of palmitoylation
Gurriaran-Rodriguez, U.; Datzkiw, D.; Radusky, L.; Esper, M.; Xiao, F.; Ming, H.; Fisher, S.; Rojas, M. J.; De Repentigny, Y.; Kothary, R.; Rojas, A. L.; Serrano, L.; Hierro, A.; Rudnicki, M. A.
10.1101/2023.05.30.542914 — molecular biology — Posted on 2023-05-30
100 Chronic high-sugar diet in adulthood protects Caenorhabditis elegans from 6-OHDA induced dopaminergic neurodegeneration
Morton, K. S.; Hartman, J. S.; Heffernan, N.; Ryde, I.; Kenny-Ganzert, I. W.; Meng, L.; Sherwood, D. R.; Meyer, J. N.
10.1101/2023.05.29.542737 — pharmacology and toxicology — Posted on 2023-05-31
101 ChromaX: a fast and scalable breeding program simulator
Younis, O. G.; Turchetta, M.; Ariza Suarez, D.; Yates, S.; Studer, B.; Athanasiadis, I. N.; Krause, A.; Buhmann, J. M.; Corinzia, L.
10.1101/2023.05.29.542709 — bioinformatics — Posted on 2023-05-31
102 Genetically Encodable in situ Gelation Redox-Responsive Collagen-Like Protein Hydrogel for Accelerating Diabetic Wound Healing
Jia, S.; Wang, J.; Wang, X.; Liu, X.; Li, S.; Li, Y.; Li, J.; Wang, J.; Man, S.; Guo, Z.; Sun, Y.; Jia, Z.; Wang, L.; Li, X.
10.1101/2023.05.29.542680 — bioengineering — Posted on 2023-05-31
103 Pseudouridine guides germline small RNA transport and epigenetic inheritance
Herridge, R. P.; Dolata, J.; Migliori, V.; de Santis Alves, C.; Borges, F.; Van Ex, F.; Lin, A.; Bajczyk, M.; Leonardi, T.; Hendrick, A.; Schorn, A. J.; Kouzarides, T.; Martienssen, R. A.
10.1101/2023.05.27.542553 — genetics — Posted on 2023-05-31
104 HUWE1 Amplifies Ubiquitin Modifications to Broadly Stimulate Clearance of Proteins and Aggregates
Zhou, M.; Fang, R.; Colson, L.; Donovan, K.; Hunkeler, M.; Chen, S.; Song, Y.; Zhang, C.; Lee, D.-h.; Bradshaw, G.; Eisert, R.; Ye, Y.; Kalocsay, M.; Goldberg, A.; Fischer, E. S.; Lu, Y.
10.1101/2023.05.30.542866 — molecular biology — Posted on 2023-05-30
105 A quantitative and site-specific atlas of the in vivo citrullinome reveals widespread existence of citrullination
Rebak, A.; Hendriks, I. A.; Buch-Larsen, S. C.; Elsborg, J. D.; Kirsch, R.; Doncheva, N. T.; Jensen, L. J.; Christophorou, M. A.; Nielsen, M. L.
10.1101/2022.12.22.521572 — molecular biology — Posted on 2023-05-31
106 The carbapenem inoculum effect provides insight into the molecular mechanisms underlying carbapenem resistance in Enterobacterales
Cartagena, A. J.; Taylor, K. L.; Smith, J. T.; Manson, A. L.; Earl, A. M.; Pierce, V. M.; Bhattacharyya, R. P.
10.1101/2023.05.23.541813 — microbiology — Posted on 2023-05-30
107 Transcriptomic analysis of sorted lung cells revealed a proviral activity of the NF- κB pathway towards SARS-CoV-2
Bhargava, A.; Szachnowski, U.; Chazal, M.; Foretek, D.; Aicher, S.-M.; Pipoli da Fonseca, J.; Jeannin, P.; Beauclair, G.; Monot, M.; Morillon, A.; Jouvenet, N.
10.1101/2022.02.25.481978 — microbiology — Posted on 2023-05-30
108 HMGB1 acts as an agent of host defense at the gut mucosal barrier
Overstreet, A.-M. C.; Anderson, B.; Burge, M.; Zhu, X.; Tao, Y.; Cham, C.; Michaud, B.; Horam, S.; Sangwan, N.; Dwidar, M.; Liu, X.; Santos, A.; Finney, C.; Dai, Z.; Leone, V.; Messer, J. S.
10.1101/2023.05.30.542477 — microbiology — Posted on 2023-05-30
109 The appearance of sugI mixed loci in three individuals during treatment for MDR-TB, supports the involvement of sugI in Mycobacterium tuberculosis d-cycloserine resistance in vivo.
Anthony, R. M.; Molemans, M.; Akkwerman, O.; Sturkenboom, M. G. G.; Mulder, A.; de Zwaan, R.; van Soolingen, D.; Alffenaar, J.-W.; van Leth, F. C. M.; Ghimire, S.; Yastskevich, N.; Skrahina, A.; Ciobanu, N.; Turcan, N.; Crudu, V.
10.1101/2023.05.30.542839 — microbiology — Posted on 2023-05-30
110 INTRA- AND INTER-HOST EVOLUTION OF HUMAN NOROVIRUS IN HEALTHY ADULTS
Ramani, S.; Javornik Cregeen, S. J.; Surathu, A.; Neill, F. H.; Muzny, D. M.; Doddapaneni, H.; Menon, V. K.; Hoffman, K. L.; Ross, M. C.; Metcalf, G.; Opekun, A. R.; Graham, D. Y.; Gibbs, R. A.; Petrosino, J. F.; Estes, M. K.; Atmar, R. L.
10.1101/2023.05.30.542907 — microbiology — Posted on 2023-05-30
115 Assessing the validity of a calcifying oral biofilm model as a suitable proxy for dental calculus
Bartholdy, B. P.; Velsko, I. M.; Gur-Arieh, S.; Fagernäs, Z.; Warinner, C.; Henry, A. G.
10.1101/2023.05.23.541904 — microbiology — Posted on 2023-05-30
119 Host subversion of bacterial metallophore usage drives copper intoxication
Hossain, S.; Morey, J. R.; Neville, S. L.; Ganio, K.; Radin, J. N.; Norambuena, J.; Boyd, J. M.; McDevitt, C. A.; Kehl-Fie, T. E.
10.1101/2023.05.30.542972 — microbiology — Posted on 2023-05-31
123 Antibodies against SARS-CoV-2 control complement-induced inflammatory responses to SARS-CoV-2
Bermejo-Jambrina, M.; van der Donk, L. E. H.; van Hamme, J. L.; Wilflingseder, D.; de Bree, G.; Prins, M.; de Jong, M.; Nieuwkerk, P.; van Gils, M. J.; Kootstra, N. A.; Geijtenbeek, T.
10.1101/2023.05.29.542735 — immunology — Posted on 2023-05-30
126 Lymphoid tissues contribute to viral clonotypes present in plasma at early post-ATI in SIV-infected rhesus macaques
Solis-Leal, A.; Boby, N.; Mallick, S.; Cheng, Y.; Wu, F.; De La Torre, G.; Dufour, J.; Alvarez, X.; Shivanna, V.; Liu, Y.; Fennessey, C. M.; Lifson, J. D.; Li, Q.; Keele, B. F.; Ling, B.
10.1101/2023.05.30.542512 — immunology — Posted on 2023-05-30
127 OCA-B/Pou2af1 is sufficient to promote CD4+ T cell memory and prospectively identifies memory precursors
Sun, W.; Hughes, E. P.; Kim, H.; Perovanovic, J.; Charley, K. R.; Du, J.; Ibarra, A.; Hale, J. S.; Williams, M. A.; Tantin, D.
10.1101/2022.09.21.508912 — immunology — Posted on 2023-05-30
130 Chemogenetic approaches reveal dual functions of microglia in epilepsy
Dheer, A.; Bosco, D. B.; Zheng, J.; Wang, L.; Zhao, S.; Haruwaka, K.; Yi, M.-H.; Barath, A.; Tian, D.; Wu, L.-J.
10.1101/2023.05.28.542660 — neuroscience — Posted on 2023-05-31
133 Forward and backward blocking in statistical learning
Nazli, I.; Ferrari, A.; Huber-Huber, C.; de Lange, F. P.
10.1101/2022.02.07.479428 — neuroscience — Posted on 2023-05-31
134 Using the visual cliff assay to assess binocular deficits in amblyopic mice
De Jesus-Cortes, H.; Bowen, D. A.; Reilly-Andujar, F.; Lu, S.; Gaier, E. D.; Bear, M. F.
10.1101/2023.05.29.542767 — neuroscience — Posted on 2023-05-31
135 Genomewide paired DNA-RNAseq analyses to discover intronic splice mutation hotspots in neurological disorders
Wang, Y.; van Dijk, C.; Timpanaro, I.; Hop, P. J.; Kenna, B.; Kooyman, M.; Aronica, E.; Pasterkamp, R. J.; van den Berg, L.; Cooper-Knock, J.; Project MinE ALS sequencing consortium, ; NYGC ALS consortium, ; Veldink, J.; Kenna, K.
10.1101/2023.05.30.542855 — bioinformatics — Posted on 2023-05-31
136 Synaptic architecture of leg and wing motor control networks in Drosophila
Lesser, E.; Azevedo, A. W.; Phelps, J. S.; Elabbady, L.; Cook, A. P.; Mark, B.; Kuroda, S.; Sustar, A.; Moussa, A. J.; Dallmann, C. J.; Agrawal, S.; Lee, S.-Y. J.; Pratt, B. G.; Skutt-Kakari, K.; Gerhard, S.; Lu, R.; Kemnitz, N.; Lee, K.; Halageri, A.; Castro, M.; Ih, D.; Gager, J.; Tammam, M.; Dorkenwald, S.; Collman, F. C.; Schneider-Mizell, C. M.; Brittain, D.; Jordan, C. S.; Seung, H. S.; Macrina, T.; Dickinson, M. H.; Lee, W.-C. A.; Tuthill, J. C.
10.1101/2023.05.30.542725 — neuroscience — Posted on 2023-05-31
137 Poly(ADP-ribose) mediates bioenergetic defects and redox imbalance in neurons following oxygen and glucose deprivation
Hossain, M. I.; Lee, J. H.; Gagne, J.-P.; Khan, J.; Poirier, G. G.; Dawson, V. L.; Dawson, T. M.; Anadrabi, S. A.
10.1101/2023.05.30.542910 — neuroscience — Posted on 2023-05-31
138 Functional identification of cis-regulatory long noncoding RNAs at controlled false-discovery rates
Chouvardas, P.; Dhaka, B.; Zimmerli, M.; Hanhart, D.; Moser, M.; Guillen-Ramirez, H. A.; Mishra, S.; Esposito, R.; Polidori, T.; Widmer, M.; Garcia-Perez, R.; Kruithof-de Julio, M.; Pervouchine, D. D.; Mele, M.; Johnson, R.
10.1101/2022.09.18.508380 — genomics — Posted on 2023-05-31
139 Progressive excitability changes in the medial entorhinal cortex in the 3xTg mouse model of Alzheimer's disease pathology
Chen, L.; Christenson Wick, Z.; Vetere, L. M.; Vaughan, N.; Jurkowski, A.; Galas, A.; Diego, K. S.; Philipsberg, P.; Cai, D. J.; Shuman, T.
10.1101/2023.05.30.542838 — neuroscience — Posted on 2023-05-30
141 Using the visual cliff assay to assess binocular deficits in amblyopic mice
De Jesus-Cortes, H.; Bowen, D. A.; Reilly-Andujar, F.; Lu, S.; Gaier, E. D.; Bear, M. F.
10.1101/2023.05.29.542767 — neuroscience — Posted on 2023-05-30
142 A dual hit of α-synuclein internalization and immune challenge leads to formation and maintenance of Lewy body-like inclusions in human dopaminergic neurons
Bayati, A.; Ayoubi, R.; Zorca, C. E.; Aguila, A.; Han, C.; Banks, E.; Nguyen-Renou, E.; Luo, W.; shlaifer, i.; Del Cid-Pellitero, E.; Yaqubi, M.; Fon, E. A.; Stratton, J. A.; Durcan, T.; Nahirney, P.; McPherson, P. S.
10.1101/2023.05.29.542776 — neuroscience — Posted on 2023-05-30
145 Maintenance of pig brain function under extracorporeal pulsatile circulatory control (EPCC)
Shariff, M.; Dobariya, A.; Albaghdadi, O.; Awkal, J.; Moussa, H.; Reyes, G.; Syed, M.; Hart, R.; Longfellow, C.; Douglass, D.; El Ahmadieh, T. Y.; Good, L. B.; Jakkamsetti, V.; Kathote, G.; Angulo, G.; Ma, Q.; Brown, R.; Dunbar, M.; Shelton, J. M.; Evers, B. M.; Patnaik, S.; Hoffmann, U.; Hackmann, A.; Mickey, B.; Peltz, M.; Jessen, M. E.; Pascual, J. M.
10.1101/2023.05.28.542663 — neuroscience — Posted on 2023-05-30
149 Structural evidence for MADS-box type I family expansion seen in new assemblies of A. arenosa and A. lyrata
Bramsiepe, J.; Krabberod, A. K.; Bjerkan, K. N.; Alling, R. M.; Johannessen, I. M.; Hornslien, K. S.; Miller, J. R.; Brysting, A. K.; Grini, P. E.
10.1101/2023.05.30.542816 — plant biology — Posted on 2023-05-31
153 Rank-based deep learning from citizen-science data to model plant communities
Brun, P.; Karger, D. N.; Zurell, D.; Descombes, P.; de Witte, L.; de Lutio, R.; Wegner, J. D.; Zimmermann, N. E.
10.1101/2023.05.30.542843 — ecology — Posted on 2023-05-31
154 Visual deprivation during mouse critical period reorganizes network-level functional connectivity
Chen, S.; Rahn, R. M.; Bice, A. R.; Gaines, S. H.; Hengen, K. B.; Dougherty, J. D.; Culver, J. P.
10.1101/2023.05.30.542957 — neuroscience — Posted on 2023-05-31
156 Altered methionine metabolism impacts phenylpropanoid production and plant development in Arabidopsis thaliana
Shin, D.; Perez, V. C.; Dickinson, G. K.; Zhao, H.; Dai, R.; Tomiczek, B. M.; Cho, K. H.; Zhu, N.; Koh, J.; Grenning, A.; Kim, J.
10.1101/2023.05.29.542770 — plant biology — Posted on 2023-05-31
157 Caspase-2 is essential for proliferation and self-renewal of nucleophosmin-mutated acute myeloid leukemia.
Sakthivel, D.; Brown-Suedel, A. N.; Keane, F.; Huang, S.; Mc Sherry, K.; Charendoff, C. I.; Dunne, K. P.; Robichaux, D. J.; Le, B.; Shin, C. S.; Carisey, A. F.; Flanagan, J. M.; Bouchier-Hayes, L.
10.1101/2023.05.29.542723 — cancer biology — Posted on 2023-05-30
159 The variation and evolution of complete human centromeres
Logsdon, G. A.; Rozanski, A. N.; Ryabov, F.; Potapova, T.; Shepelev, V. A.; Mao, Y.; Rautiainen, M.; Koren, S.; Nurk, S.; Porubsky, D.; Lucas, J. K.; Hoekzema, K.; Munson, K. M.; Gerton, J. L.; Phillippy, A. M.; Alexandrov, I. A.; Eichler, E. E.
10.1101/2023.05.30.542849 — genomics — Posted on 2023-05-31
162 ABCB1 overexpression through locus amplification represents an actionable target to combat paclitaxel resistance in pancreatic cancer cells
Bergonzini, C.; Gregori, A.; Hagens, T. M. S.; van der Noord, V. E.; van de Water, B.; Zweemer, A. J. M.; Capula, M.; Mantini, G.; Botto, A.; Finamore, F.; Garajova, I.; McDonnell, L. A.; Schmidt, T.; Giovannetti, E.; Danen, E. H. J.
10.1101/2023.05.30.542412 — cancer biology — Posted on 2023-05-30
170 The genomic and cellular basis of biosynthetic innovation in rove beetles
Kitchen, S. A.; Naragon, T. H.; Bruckner, A.; Ladinsky, M. S.; Quinodoz, S. A.; Badroos, J. M.; Viliunas, J. W.; Wagner, J. M.; Miller, D. R.; Yousefelahiyeh, M.; Antoshechkin, I. A.; Eldredge, K. T.; Pirro, S.; Guttman, M.; Davis, S. R.; Aardema, M. L.; Parker, J.
10.1101/2023.05.29.542378 — evolutionary biology — Posted on 2023-05-30
171 Neuropsychology of cognitive aging in rhesus monkeys
Baxter, M. G.; Roberts, M. T.; Roberts, J. A.; Rapp, P. R.
10.1101/2023.05.30.542956 — neuroscience — Posted on 2023-05-30
173 Characterizing the quality metric in genotype imputation
Shi, M.; Tanikawa, C.; Munter, H. M.; Akiyama, M.; Koyama, S.; Tomizuka, K.; Matsuda, K.; Lathrop, G. M.; Terao, C.; Koido, M.; Kamatani, Y.
10.1101/2023.05.30.542466 — bioinformatics — Posted on 2023-05-30
176 The developmental gene disco regulates diel-niche evolution in adult moths
Sondhi, Y.; Messcher, R. L.; Bellantuano, A. J.; Storer, C. G.; Cinel, S. D.; Godfrey, R. K.; Glass, D.; St. Laurent, R. A.; Hamilton, C. A.; Earl, C.; Brislawn, C. J.; Kitching, I. J.; Bybee, S. M.; Theobald, J. C.; Kawahara, A. Y.
10.1101/2023.05.28.542320 — evolutionary biology — Posted on 2023-05-30
187 New strategy for bioplastic and exopolysaccharides production: Enrichment of field microbiomes with cyanobacteria
Altamira-Algarra, B.; Rueda, E.; Lage, A.; San Leon, D.; Martinez-Blanch, J. F.; Nogales, J.; Garcia, J.; Gonzalez-Flo, E.
10.1101/2023.05.30.542819 — bioengineering — Posted on 2023-05-30
188 Engineering a highly durable adeno-associated virus receptor for analytical applications
Yoshida, K.; Tsunekawa, Y.; Kurihara, K.; Watanabe, K.; Makino, Y.; Tanaka, T.; Ide, T.; Okada, T.
10.1101/2023.05.29.542019 — bioengineering — Posted on 2023-05-30
192 Uncovering structural features that control substrate specificity in a Lactobacillus chlorogenic acid esterase
Omori, K. K.; Okumura, T. L. S.; Carl, N. B.; Dinn, B. T.; Ly, D.; Sacapano, K. N.; Tajii, A.; Owens, C. P.
10.1101/2023.05.30.542953 — biochemistry — Posted on 2023-05-30
193 Small Molecule in situ Resin Capture - A Compound First Approach to Natural Product Discovery.
Bogdanov, A.; Salib, M. N.; Chase, A. B.; Hammerlindl, H.; Muskat, M. N.; Luedtke, S.; Barbosa Da Silva, E.; O'Donoghue, A. J.; Wu, L. F.; Altschuler, S. J.; Molinski, T. F.; Jensen, P. R.
10.1101/2023.03.02.530684 — biochemistry — Posted on 2023-05-30
195 Gene expression QTL mapping in stimulated iPSC-derived macrophages provides insights into common complex diseases.
Panousis, N. I.; Garwany, O. E.; Knights, A.; Rop, J. C.; Kumasaka, N.; Imaz, M.; Vilarino, L. B.; Tsingene, A.; Barnett, A.; Gomez, C.; Anderson, C.; Gaffney, D. J.
10.1101/2023.05.29.542425 — genomics — Posted on 2023-05-30
198 Common evolutionary origins of the bacterial glycyl tRNA synthetaseand alanyl tRNA synthetase
Alvarez-Carreno, C.; Arciniega, M.; Ribas de Pouplana, L.; Petrov, A. S.; Hernandez-Gonzalez, A.; Valencia-Sanchez, M. I.; Williams, L. D.; Torres-Larios, A.
10.1101/2023.05.29.542759 — evolutionary biology — Posted on 2023-05-30
205 Extrastriate activity reflects the absence of local retinal input
Urale, P. W. B.; Zhu, L.; Gough, R.; Arnold, D. H.; Schwarzkopf, D. S.
10.1101/2023.05.15.540895 — neuroscience — Posted on 2023-05-30
207 Genetically engineering endothelial niche in human kidney organoids enables multilineage maturation, vascularization, and de novo cell types
Maggiore, J. C.; LeGraw, R.; Przepiorski, A.; Velazquez, J.; Chaney, C.; Streeter, E.; Silva-Barbosa, A.; Franks, J.; Hislop, J.; Hill, A.; Wu, H.; Pfister, K.; Howden, S. E.; Watkins, S. C.; Little, M.; Humphreys, B.; Watson, A.; Stolz, D. B.; Kiani, S.; Davidson, A. J.; Carroll, T. J.; Cleaver, O. J.; Sims-Lucas, S.; Ebrahimkhani, M. R.; Hukriede, N. A.
10.1101/2023.05.30.542848 — bioengineering — Posted on 2023-05-30
210 Kit Ligand and Kit receptor tyrosine kinase sustain synaptic inhibition of Purkinje Cells
Zaman, T.; Vogt, D.; Prokop, J.; Alsabia, Q. A.; Simms, G.; Stafford, A.; Luikart, B.; Williams, M. R.
10.1101/2023.05.30.542885 — neuroscience — Posted on 2023-05-30
215 Cell specification and functional interactions in the pig blastocyst inferred from single cell transcriptomics
Dufour, A.; Kurilo, C.; Stockl, J. B.; Laloe, D.; Bailly, Y.; Manceau, P.; Martins, F.; Turhan, A. G.; Ferchaud, S.; Pain, B.; Frohlich, T.; Foissac, S.; Artus, J.; Acloque, H.
10.1101/2023.05.30.542847 — developmental biology — Posted on 2023-05-30
217 Similarity index of ex-Gaussian reaction time signatures
Manjarrez, E.; DeLuna-Castruita, A.; Lizarraga-Cortes, V.; Flores, A.
10.1101/2023.05.29.542684 — neuroscience — Posted on 2023-05-30
220 Inhibition of cAMP signaling prevents congenital heart defects counteracting oxidative stress in Pde2A deficient embryos
Pellegrini, M.; Cardarelli, S.; Naro, F.; DeAngelis, L.; Biglietto, M.; Orsini, T.; Fustaino, V.; monaco, L.; de Oliveira doRego, A. G.; Liccardo, F.; Masciarelli, S.; Fazi, F.
10.1101/2023.05.29.542779 — developmental biology — Posted on 2023-05-30
222 Genetic identification of novel medullary neurons underlying congenital central hypoventilation syndrome
Cui, K.; Xia, Y.; Patnaik, A.; Lowenstein, E. D.; Isik, E. G.; Knorz, A. L.; Airaghi, L.; Crotti, M.; Studer, M.; Rijli, F. M.; Nothwang, H. G.; Hernandez-Miranda, L. R.
10.1101/2023.05.29.542652 — neuroscience — Posted on 2023-05-30
223 VEGF-C promotes brain-derived fluid drainage, confers neuroprotection, and improves stroke outcomes
Simoes Braga Boisserand, L.; Bouchart, J.; Geraldo, L. H. M.; Lee, S.; Sanganahalli Ganganna, B.; Parent, M.; Zhang, S.; Xue, Y.; Skarica, M.; Guegan, J.; Li, M.; Liu, X.; Poulet, M.; Askanase, M.; Osherov, A.; Spajer, M.; El Kamouh, M.-R.; Eichmann, A.; Alitalo, K. K.; Zhou, J.; Sestan, N.; Sansing, L.; Benveniste, H.; Hyder, F.; thomas, j.-l.
10.1101/2023.05.30.542708 — neuroscience — Posted on 2023-05-30
224 Multiple myeloma long-term survivors display sustained immune alterations decades after first line therapy
Lutz, R.; Gruenschlaeger, F.; Simon, M.; Bauer, M.; Yousefian, S.; Beumer, N.; Jopp-Saile, L.; Awwad, M.; Steinbuss, G.; Sedlmeier, A.; Boch, T.; Vonficht, D.; Baertsch, M.-A.; Durie, B.; Weinhold, N.; Raab, M.; Wickenhauser, C.; Trumpp, A.; Mueller-Tidow, C.; Huebschmann, D.; Brors, B.; Goldschmidt, H.; Imbusch, C.; Hundemer, M.; Haas, S.
10.1101/2023.05.27.542555 — cancer biology — Posted on 2023-05-30
226 Low-dose carbon monoxide therapy is neuroprotective in rodent models of Parkinson's disease
Rose, K. N.; Zorlu, M.; Xue, X.; Cai, W.; Lin, S.; Schwarzschild, M.; Chen, X.; Gomperts, S. N.
10.1101/2023.05.27.542565 — neuroscience — Posted on 2023-05-30
227 FOXK2 amplification and overexpression promotes breast cancer development and chemoresistance
Yu, Y.; Cao, W.-M.; Cheng, F.; Shi, Z.; Han, L.; Yi, J.-L.; da Silva, E. M.; Dopeso, H.; Chen, H.; Yang, J.; Wang, X.; Zhang, C.; Zhang, H.
10.1101/2023.05.28.542643 — cancer biology — Posted on 2023-05-30
229 A non-image-forming visual circuit mediates the innate fear of heights
Shang, W.; Xie, S.; Feng, W.; Jia, J.; Cao, X.; Li, Z.; Li, J.; Gu, Y.; Shi, H.; Lin, L.; Yuan, X.; Pan, Y.-H.
10.1101/2023.05.27.542556 — neuroscience — Posted on 2023-05-30
232 Glaucoma-associated Optineurin mutations increase transmitophagy in a vertebrate optic nerve
Jeong, Y.; Davis, c.-h.; Muscarella, A.; Deshpande, V.; Kim, K.-Y.; Ellisman, M.; Marsh-Armstrong, N.
10.1101/2023.05.26.542507 — neuroscience — Posted on 2023-05-30
237 Imaging the microscopic viscoelastic anisotropy in living cells
Keshmiri, H.; Cikes, D.; Samalova, M.; Schindler, L.; Appel, L.-M.; Urbanek, M.; Yudushkin, I.; Slade, D.; Weninger, W. J.; Peaucelle, A.; Penninger, J.; Elsayad, K.
10.1101/2023.05.28.542585 — biophysics — Posted on 2023-05-30
238 A 3D-printed flow-cell for on-grid purification of electron microscopy samples directly from lysate
Ramlaul, K.; Feng, Z.; Canavan, C.; de Martin Garrido, N.; Carreno, D.; Crone, M.; Jensen, K. E.; Li, B.; Barnet, H.; Riglar, D. T.; Freemont, P. S.; Miller, D.; Aylett, C. H. S.
10.1101/2023.03.17.533159 — biophysics — Posted on 2023-05-30
241 Genetics of skeletal proportions in two different populations
Bartell, E.; Lin, K.; Tsuo, K.; Gan, W.; Vedantam, S.; Cole, J. B.; Baronas, J. M.; Yengo, L.; Marouli, E.; Amariuta, T.; Chen, Z.; Li, L.; GIANT Consortium, ; Renthal, N. E.; Jacobsen, C. M.; Salem, R.; Walters, R. G.; Hirschhorn, J. N.
10.1101/2023.05.22.541772 — genetics — Posted on 2023-05-30
242 Using drivers and transmission pathways to identify SARS-like coronavirus spillover risk hotspots
Muylaert, R. L.; Wilkinson, D. A.; Kingston, T.; D`Odorico, P.; Rulli, M. C.; Galli, N.; John, R. S.; Alviola, P.; Hayman, D. T. S.
10.1101/2022.12.08.518776 — ecology — Posted on 2023-05-30
243 Dual-color GRAB sensors for monitoring spatiotemporal serotonin release in vivo
Deng, F.; Wan, J.; Li, G.; Dong, H.; Xia, X.; Wang, Y.; Li, X.; Zhuang, C.; Zheng, Y.; Liu, L.; Yan, Y.; Feng, J.; Zhao, Y.; Xie, H.; Li, Y.
10.1101/2023.05.27.542566 — neuroscience — Posted on 2023-05-30
245 In-silico testing of new pharmacology for restoring inhibition and human cortical function in depression
Guet-McCreight, A.; Moradi-Chameh, H.; Mazza, F.; Prevot, T. D.; Valiante, T. A.; Sibille, E.; Hay, E.
10.1101/2023.02.22.529541 — neuroscience — Posted on 2023-05-30
246 Detection and identification of transposable element transcripts using Long Read RNA-seq in Drosophila germline tissues
Rebollo, R.; Cumunel, E.; Mary, A.; Sabot, F.; Burlet, N.; Gillet, B.; Hughes, S.; Siqueira Oliveira, D.; Goubert, C.; Fablet, M.; Vieira, C.; Lacroix, V.
10.1101/2023.05.27.542554 — bioinformatics — Posted on 2023-05-30
251 Site-Specific Phosphorylation of ZYG-1 Regulates ZYG-1 Stability and Centrosome Number
Medley, J. C.; Yim, N.; DiPanni, J.; Schaffou, B.; Sebou, B.; Cramer, E.; Wu, C.; Kabara, M.; Song, M. H.
10.1101/2023.05.07.539463 — cell biology — Posted on 2023-05-30
254 Adaptor protein complex 2 in the orbitofrontal cortexpredicts alcohol use disorder
Mulholland, P. J.; Berto, S.; Wilmarth, P.; McMahan, C.; Ball, L.; Woodward, J.
10.1101/2023.05.28.542637 — neuroscience — Posted on 2023-05-30
255 Mapping the daily rhythmic transcriptome in the diabetic retina
Silk, R. P.; Winter, H. R.; Dkhissi-Benyahya, O.; Evans-Molina, C.; Stitt, A. W.; Tiwari, V. K.; Simpson, D. A.; Beli, E.
10.1101/2023.05.27.542572 — bioinformatics — Posted on 2023-05-30
257 Evolution towards simplicity in bacterial small heat shock protein system
Karas, P.; Kochanowicz, K.; Pitek, M.; Domanski, P.; Obuchowski, I.; Tomiczek, B.; Liberek, K.
10.1101/2023.05.18.541272 — biochemistry — Posted on 2023-05-30
259 Large differences in collateral blood vessel abundance among individuals arise from multiple genetic variants
Faber, J. E.; Zhang, H.; Xenakis, J. G.; Bell, T. A.; Hock, P.; de Villena, F. P.-M.; Ferris, M. T.; Rzechorzek, W.
10.1101/2023.05.28.542633 — genetics — Posted on 2023-05-30
260 Delay of human early development via in vitro diapause
Iyer, D.; van der Weijden, V.; Heidari Khoei, H.; McCarthy, A.; Rayon, T.; Simon, C.; Dunkel, I.; Wamaitha, S.; Schulz, E.; Niakan, K.; Rivron, N. C.; Bulut-Karslioglu, A.
10.1101/2023.05.29.541316 — developmental biology — Posted on 2023-05-30
262 Neuronal Tau Pathology Worsens Late Phase White Matter Degeneration After Traumatic Brain Injury in Transgenic Mice
Yu, F.; Iacono, D.; Perl, D. P.; Lai, C.; Gill, J.; Le, T. Q.; Lee, P.; Sukumar, G.; Armstrong, R. C.
10.1101/2023.05.27.542567 — neuroscience — Posted on 2023-05-30
264 Consecutive treatments of methamphetamine promote the 4 development of cardiac pathological symptoms in zebrafish
Zhang, J.; Nguyen, H. A.; Jilani, D.; Torres, R. S. T.; Schmiess-Heine, L.; Le, T. N.; Xia, X.; Cao, H.
10.1101/2023.05.28.542664 — physiology — Posted on 2023-05-30
266 PXPermute: Unveiling staining importance in multichannel fluorescence microscopy
Boushehri, S. S.; Kornivetc, A.; Waibel, D.; Kazeminia, S.; Schmich, F.; Marr, C.
10.1101/2023.05.28.542646 — bioinformatics — Posted on 2023-05-30
268 STEM: A Method for Mapping Single-cell and Spatial Transcriptomics Data with Transfer Learning
Hao, M.; Luo, E.; Chen, Y.; Wu, Y.; Li, C.; Chen, S.; Gao, H.; Bian, H.; Wei, L.; Zhang, X.
10.1101/2022.09.23.509186 — bioinformatics — Posted on 2023-05-30
273 Neurophysiology of Reciprocal Influence of Cognition and Emotion in Pianistic Performances
Higuchi, M. K. K.; Sanchez, T. A.; Ramos, L. R.; Fornari, J. E.; de Araujo, D. B.; Leite, J. P.
10.1101/2023.05.28.542541 — neuroscience — Posted on 2023-05-30
275 Knowledge, attitudes and biosecurity practices among the small-scale dairy farmers in Sylhet District, Bangladesh
Chowdhury, T.; Ahmed, J.; Hossain, M. T.; Roy, M. C.; Zaman, M. A.-U.; Uddin, M. N.; Rahman, M. M.; Kabir, M. G.; Hossain, F. M. A.
10.1101/2023.05.28.542608 — scientific communication and education — Posted on 2023-05-30
278 Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels
Giese, A. P. J.; Weng, W.-H.; Kindt, K. S.; Chang, V. H. H.; Montgomery, J. S.; Ratzan, E. M.; Beirl, A. J.; Aponte Rivera, R.; Lotthammer, J. M.; Walujkar, S.; Foster, M. P.; Zobeiri, O. A.; Holt, J. R.; Riazuddin, S.; Cullen, K. E.; Sotomayor, M.; Ahmed, Z. M.
10.1101/2023.05.26.542533 — neuroscience — Posted on 2023-05-30
282 Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT)
Joodaki, M.; Shaigan, M.; Parra, V.; D. Buelow, R.; Kuppe, C.; L. Holscher, D.; Cheng, M.; S. Nagai, J.; Bouteldja, N.; Tesar, V.; Barratt, J.; Roberts, I. S. D.; Coppo, R.; Kramann, R.; Boor, P.; G. Costa, I.
10.1101/2022.12.16.520739 — bioinformatics — Posted on 2023-05-30
284 Optimizing Cell Therapy by Sorting Cells with High Extracellular Vesicle Secretion
Koo, D.; Cheng, X.; Udani, S.; Zhu, D.; Li, J.; Hall, B.; Tsubamoto, N.; Hu, S.; Ko, J.; Cheng, K.; Di Carlo, D.
10.1101/2023.05.29.542772 — bioengineering — Posted on 2023-05-30
286 Insights into the genomic features, lifestyle and therapeutic potential of B1 sub-cluster mycobacteriophages
Das, R.; Arora, R.; Nadar, K.; Saroj, S.; Singh, A. K.; Patil, S. A.; Raman, S. K.; Misra, A.; Bajpai, U.
10.1101/2023.05.30.542743 — microbiology — Posted on 2023-05-30
288 Glyceroglycolipids are essential for Burkholderia cenocepacia intracellular survival by preventing phagolysosome acidification
Shropshire, H.; Guillonneau, R.; Han, Z.; Jones, R.; Ahmed, S.; Garcia Romero, I.; Aberdeen, I.; Nezis, I.; Valvano, M. A.; Scanlan, D.; Chen, Y.
10.1101/2023.05.30.542800 — microbiology — Posted on 2023-05-30
289 Non-Markovian memory and emergent simplicities in the stochastic and plastic adaptation of individual cells to dynamic environments
Joshi, K.; Ziegler, K. F.; Roy, S.; Wright, C. S.; Gandhi, R.; Stonecipher, J.; Biswas, R. R.; Iyer-Biswas, S.
10.1101/2023.05.27.542601 — biophysics — Posted on 2023-05-30
291 Red blood cell-derived extracellular vesicles with miR-204 mimic loading for pediatric neuroblastoma treatment
Chiangjong, W.; Panachan, J.; Keadsanti, S.; Newburg, D. S.; Morrow, A. L.; Hongeng, S.; Chutipongtanate, S.
10.1101/2023.05.29.542704 — bioengineering — Posted on 2023-05-30
293 Understanding ATP binding to DosS catalytic domain with a short ATP-lid
Larson, G.; Windsor, P.; Smithwick, E.; Shi, K.; Aihara, H.; Rama Damodaran, A.; Bhagi-Damodaran, A.
10.1101/2023.05.29.542785 — biochemistry — Posted on 2023-05-30
294 Improved gene annotation of the fungal wheat pathogen Zymoseptoria tritici based on combined Iso-Seq and RNA-Seq evidence
Lapalu, N.; Lamothe, L.; Petit, Y.; Genissel, A.; Delude, C.; Feurtey, A.; Abraham, L. N.; Smith, D.; King, R.; Renwick, A.; Appertet, M.; Sucher, J.; Steindorff, A. S.; Goodwin, S. B.; Kema, G. H. J.; Grigoriev, I. V.; Hane, J.; Rudd, J.; Stukenbrock, E.; Croll, D.; Scalliet, G.; Lebrun, M.-H.
10.1101/2023.04.26.537486 — genomics — Posted on 2023-05-30
297 Oxidation-reduction imaging of myoglobin unveils two-phase oxidation in the reperfused myocardium.
BIDAUX, G.; Badawi, S.; Leboullenger, C.; Chourrout, M.; Gouriou, Y.; Paccalet, A.; Pillot, B.; Augeul, L.; Bolbos, R.; bongiovani, a.; Mewton, N.; Bochaton, T.; Ovize, M.; tardivel, m.; Kurdi, M.; Canet-Soulas, E.; Crola Da Silva, C.
10.1101/2023.05.26.542538 — pathology — Posted on 2023-05-30
299 A 3D cell-free bone model shows collagen mineralization is driven and controlled by the matrix
Van der Meijden, R. H. M.; Daviran, D.; Rutten, L.; Walboomers, F.; Macias-Sanchez, E.; Sommerdijk, N.; Akiva, A.
10.1101/2022.10.24.513466 — biochemistry — Posted on 2023-05-30
302 The apicoplast is important for the viability and persistence of Toxoplasma gondii bradyzoites
Sanchez, S. G.; Bassot, E.; Cerutti, A.; Nguyen, H. M.; Aïda, A.; Blanchard, N.; Besteiro, S.
10.1101/2023.01.13.523885 — microbiology — Posted on 2023-05-30
304 Lyssa excreta: Defining parameters for fecal samples as a rabies virus surveillance method
Walker, F. M.; Upton, J. R.; Erickson, D.; Barrand, Z.; Brock, B.; Valentine, M.; Federman, E. L.; Froehlich, E. M.; Van Pelt, L. I.; Hastings, L.; Bergman, D. L.; Engelthaler, D. M.; Hepp, C. M.
10.1101/2023.05.27.542586 — pathology — Posted on 2023-05-30
306 DNA-guided transcription factor cooperativity shapes face and limb mesenchyme
Kim, S.; Morgunova, E.; Naqvi, S.; Bader, M.; Koska, M.; Popov, A.; Luong, C.; Pogson, A.; Claes, P.; Taipale, J.; Wysocka, J.
10.1101/2023.05.29.541540 — genomics — Posted on 2023-05-29
311 Pseudouridine guides germline small RNA transport and epigenetic inheritance
Herridge, R. P.; Dolata, J.; Migliori, V.; de Santis Alves, C.; Borges, F.; Van Ex, F.; Lin, A.; Bajczyk, M.; Leonardi, T.; Hendrick, A.; Schorn, A. J.; Kouzarides, T.; Martienssen, R. A.
10.1101/2023.05.27.542553 — genetics — Posted on 2023-05-30
313 Direct Entorhinal Control of CA1 Temporal Coding
Guardamagna, M.; Chadney, O. M. T.; Stella, F.; Zhang, Q.; Kentros, C.; Battaglia, F. P.
10.1101/2023.05.27.542579 — neuroscience — Posted on 2023-05-29
315 A marker chromosome in psychosis identifies glycine decarboxylase (GLDC) as a novel regulator of neuronal and synaptic function in the hippocampus
Kambali, M.; Li, Y.; Unichenko, P.; Pliego, J. F.; Yadav, R.; Liu, J.; McGuinness, P.; Cobb, J. G.; Wang, M.; Nagarajan, R.; Lyu, J.; Vongsouthi, V.; Jackson, C. J.; Engin, E.; Coyle, J.; Shin, J.; Talkowski, M. E.; Homanics, G. E.; Bolshakov, V.; Henneberger, C.; Rudolph, U.
10.1101/2023.05.29.542745 — neuroscience — Posted on 2023-05-29
316 Phase-encoded fMRI tracks down brainstorms of natural language processing with sub-second precision
Lei, V. L. C.; Leong, T. I.; Leong, C. T.; Liu, L.; Choi, C. U.; Sereno, M. I.; Li, D.; Huang, R.-S.
10.1101/2023.05.29.542546 — neuroscience — Posted on 2023-05-29
317 Classifying high-dimensional phenotypes with ensemble learning
Devine, J.; Kurki, H. K.; Epp, J. R.; Gonzalez, P. N.; Claes, P.; Hallgrimsson, B.
10.1101/2023.05.29.542750 — bioinformatics — Posted on 2023-05-29
318 Single cell spatial analysis and biomarker discovery in Hodgkin lymphoma
Xu, A. M.; Jiang, A.; Aoki, T.; Gamboa, A.; Chong, L.; Colombo, A. R.; Yin, Y.; Lownik, J.; Takata, K.; Hav, M.; Steidl, C.; Merchant, A.
10.1101/2023.05.24.542195 — cancer biology — Posted on 2023-05-29
326 Allosteric site variants affect GTP hydrolysis on RAS
Johnson, C. W.; Fetics, S. K.; Davis, K. P.; Rodrigues, J. A.; Mattos, C.
10.1101/2023.05.29.542740 — biochemistry — Posted on 2023-05-29
327 A Framework for Designing Efficient Deep Learning-Based Genomic Basecallers
Singh, G.; Alser, M.; Khodamoradi, A.; Denolf, K.; Firtina, C.; Cavlak, M. B.; Corporaal, H.; Mutlu, O.
10.1101/2022.11.20.517297 — genomics — Posted on 2023-05-29
329 Chikungunya virus glycoproteins transform macrophages into productive viral dissemination vessels.
Li, M. M. H.; Yao, Z.; Ramachandran, S.; Huang, S.; Jami-Alahmadi, Y.; Wohlschlegel, J. A.
10.1101/2023.05.29.542714 — microbiology — Posted on 2023-05-29
330 CARD-like domains mediate anti-phage defense in bacterial gasdermin systems
Wein, T.; Johnson, A. G.; Millman, A.; Lange, K.; Yirmiya, E.; Hadary, R.; Garb, J.; Steinruecke, F.; Hill, A. B.; Kranzusch, P. J.; Sorek, R.
10.1101/2023.05.28.542683 — microbiology — Posted on 2023-05-29
332 The role of the cerebellum in learning to predict reward: evidence from cerebellar ataxia
Nicholas, J.; Amlang, C.; Lin, C.-Y.; Montaser-Kouhsari, L.; Desai, N.; Pan, M.-K.; Kuo, S.-H.; Shohamy, D.
10.1101/2022.11.04.515251 — neuroscience — Posted on 2023-05-29
340 Small immunological clocks identified by Deep Learning and Gradient Boosting
Kalyakulina, A.; Yusipov, I.; Kondakova, E.; Bacalini, M. G.; Franceschi, C.; Vedunova, M.; Ivanchenko, M.
10.1101/2022.10.28.514283 — bioinformatics — Posted on 2023-05-29
342 Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter
Tang, Q.; Sinclair, M.; Hasdemir, H.; Stein, R. A.; Karakas, E.; Tajkhorshid, E.; Mchaourab, H.
10.1101/2023.05.29.541986 — biophysics — Posted on 2023-05-29
343 Signaling mechanisms and agricultural applications of (Z)-3-Hexenyl Butyrate-mediated stomatal closure
Paya, C.; Belda-Palazon, B.; Vera-Sirera, F.; Perez-Perez, J.; Jorda, L.; Rodrigo, I.; Belles, J.; Lopez-Gresa, M. P.; Lison, P.
10.1101/2023.05.26.542418 — molecular biology — Posted on 2023-05-29
344 Development of a SARS-COV-2 monoclonal antibody panel and its applicability as a reagent in high-throughput fluorescence reduction neutralization and immunohistochemistry assays
Mattoso, G.; Cataneo, A.; Raboni, S. M.; Nogueira, M. B.; Vaz de Paula, C.; Almeida, A. C.; Rogerio, V.; Zanchin, N.; de Noronha, L.; Zanluca, C.; Duarte dos Santos, C. N.
10.1101/2023.05.29.542720 — microbiology — Posted on 2023-05-29
345 Bowel dysmotility and enteric neuron degeneration in lysosomal storage disease mice is prevented by gene therapy
Jansen, M. J.; Williams, L. L.; Wang, S.; Eultgen, E. M.; Takahashi, K.; Nelvagal, H. R.; Sharma, J.; Sardiello, M.; DeBosch, B. J.; Anderson, J. B.; Sax, S. E.; Wright, C. M.; Makita, T.; Grider, J. R.; Sands, M. S.; Heuckeroth, R.; Cooper, J. D.
10.1101/2023.05.26.542524 — neuroscience — Posted on 2023-05-29
346 No Replication of Direct Neuronal Activity-related (DIANA) fMRI in Anesthetized Mice
Choi, S.-H.; Im, G. H.; Choi, S.; Yu, X.; Bandettini, P. A.; Menon, R. S.; Kim, S.-G.
10.1101/2023.05.26.542419 — neuroscience — Posted on 2023-05-29
347 Enhanced late blight resistance by engineering an EpiC2B-insensitive immune protease
Schuster, M.; Eisele, S.; Armas Egas, L.; Kessenbrock, T.; Kourelis, J.; Kaiser, M.; van der Hoorn, R. A. L.
10.1101/2023.05.29.541874 — plant biology — Posted on 2023-05-29
353 Biochemical, biomarker, and behavioral characterization of the GrnR493X mouse model of frontotemporal dementia
Smith, D. M.; Aggarwal, G.; Niehoff, M. L.; Jones, S. A.; Banerjee, S.; Farr, S. A.; Nguyen, A. D.
10.1101/2023.05.27.542495 — neuroscience — Posted on 2023-05-29
355 The variable domain from the mitochondrial fission mechanoenzyme Drp1 promotes liquid-liquid phase separation
Posey, A. E.; Bagheri, M.; Ross, K. A.; Lanum, E. N.; Khan, M. A.; Jennings, C. M.; Harwig, M. C.; Kennedy, N. W.; Hilser, V. J.; Harden, J. L.; Hill, R. B.
10.1101/2023.05.29.542732 — biophysics — Posted on 2023-05-29
356 Dissection of anterior mesendoderm segregation at single cell level in zebrafish
Cheng, T.; Liu, X.; Dong, Y.; Xing, Y.-Y.; Liu, C.; Li, Y.-F.; Huang, Y.; Luan, J.-Y.; Liang, H.; Xu, P.-F.
10.1101/2023.05.29.542713 — developmental biology — Posted on 2023-05-29
357 Exomap1 mouse: a transgenic model for in vivo studies of exosome biology
Fordjour, F. K.; Abuelreich, S.; Hong, X.; Chatterjee, E.; Lallai, V.; Ng, M.; Saftics, A.; Deng, F.; Carnel-Amar, N.; Wakimoto, H.; Shimizu, K.; Anh Phu, T.; Vu, N. K.; Geiger, P. C.; Raffai, R. L.; Fowler, C. D.; Shimizu, K.; Das, S.; Christenson, L. K.; Jovanovic-Talisman, T.; Gould, S.
10.1101/2023.05.29.542707 — cell biology — Posted on 2023-05-29
358 The RNA-binding protein Imp specifies olfactory navigation circuitry and behavior in Drosophila
Hamid, A.; Gattuso, H.; Caglar, A. N.; Pillai, M.; Steele, T.; Gonzalez, A.; Nagel, K.; Syed, M.
10.1101/2023.05.26.542522 — neuroscience — Posted on 2023-05-29
362 Delay of human early development via in vitro diapause
Bulut-Karslioglu, A.; Iyer, D.; van der Weijden, V.; Heidari Khoei, H.; McCarthy, A.; Rayon, T.; Simon, C.; Dunkel, I.; Wamaitha, S.; Schulz, E.; Niakan, K.; Rivron, N. C.
10.1101/2023.05.29.541316 — developmental biology — Posted on 2023-05-29
364 Parabrachial nucleus activity in nociception and pain in awake mice
Smith, J.; Ji, Y.; Lorsung, R.; Breault, M.; Koenig, J.; Cramer, N. P.; Masri, R.; Keller, A.
10.1101/2023.03.22.533230 — neuroscience — Posted on 2023-05-29
365 The Tgf-β family member Gdf6Y determines the male sex in Nothobranchius furzeri by suppressing oogenesis-inducing genes
Richter, A.; Mörl, H.; Thielemann, M.; Kleemann, M.; Geissen, R.; Schwarz, R.; Albertz, C.; Koch, P.; Petzold, A.; Groth, M.; Hartmann, N.; Herpin, A.; Englert, C.
10.1101/2023.05.26.542338 — molecular biology — Posted on 2023-05-29
366 Direct prediction of intrinsically disordered protein conformational properties from sequence
Lotthammer, J. M.; Ginell, G. M.; Griffith, D.; Emenecker, R. J.; Holehouse, A. S.
10.1101/2023.05.08.539824 — biophysics — Posted on 2023-05-29
367 Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications
Singh, V.; Itoh, Y.; Del'Olio, S.; Hassan, A.; Naschberger, A.; Flygaard, R. K.; Nobe, Y.; Izumikawa, K.; Aibara, S.; Andrell, J.; Whitford, P.; Barrientos, A.; Taoka, M.; Amunts, A.
10.1101/2023.05.24.542018 — biochemistry — Posted on 2023-05-29
370 Pseudo-grading of tumor subclones using phenotype algebra
Bhattacharya, N.; Rockstroh, A.; Deshpande, S. S.; Thomas, S. K.; Chawla, S.; Solomon, P.; Fourgeux, C.; Ahuja, G.; Hollier, B.; Kumar, H.; Roquilly, A.; Poschmann, J.; Lehman, M.; Nelson, C. C.; Sengupta, D.
10.1101/2022.12.28.522060 — bioinformatics — Posted on 2023-05-29
372 Mapping memories: pulse-chase labeling reveals AMPA receptor dynamics during memory formation
Kim, D.; Park, P.; Li, X. T.; Wong-Campos, J. D.; Tian, H.; Moult, E. M.; Grimm, J. B.; Lavis, L.; Cohen, A. E.
10.1101/2023.05.26.541296 — neuroscience — Posted on 2023-05-29
377 Rab7 dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis
Gaur, P.; Rajendran, Y.; Srivastava, B.; Markandey, M.; Fishbain-Yoskovitz, V.; Mohapatra, G.; Suhail, A.; Chaudhary, S.; Tyagi, S.; Yadav, S. C.; Pandey, A. K.; Merbl, Y.; Bajaj, A.; Ahuja, V.; Srikanth, C.
10.1101/2023.02.13.528320 — cell biology — Posted on 2023-05-29
383 HSV-1 miRNAs are posttranscriptionaly edited in latently infected human ganglia
Zubkovic, A.; Gomez-Martin, C.; Parchure, A. A.; Cesarec, M.; Ferencic, A.; Rokic, F.; Jakovac, H.; Whitford, A. L.; Dochnal, S. A.; Cliffe, A. R.; Cuculic, D.; Gallo, A.; Vugrek, O.; Hackenberg, M.; Jurak, I.
10.1101/2023.05.26.542484 — microbiology — Posted on 2023-05-29
389 Breakdown in seasonal dynamics of subtropical ant communities with land-cover change
Kass, J. M.; Yoshimura, M.; Ogasawara, M.; Suwabe, M.; Hita Garcia, F.; Fischer, G.; Dudley, K. L.; Donohue, I.; Economo, E. P.
10.1101/2023.01.17.523860 — ecology — Posted on 2023-05-29
394 Ghrelin signalling in AgRP neurons links metabolic state to the sensory regulation of AgRP neural activity.
So, W. L.; Hu, J.; Jeffs, L.; Dempsey, H.; Lockie, S.; Zigman, J.; Stark, R.; Reichenbach, A.; Andrews, Z. B.
10.1101/2023.05.28.542625 — neuroscience — Posted on 2023-05-28
395 Schwann cell release of p11 induces sensory neuron hyperactivity in Fabry disease.
Waltz, T. B.; Chao, D.; Prodoehl, E. K.; Ehlers, V. L.; Dharanikota, B. S.; Dahms, N. M.; Isaeva, E.; Hogan, Q. H.; Pan, B.; Stucky, C. L.
10.1101/2023.05.26.542493 — neuroscience — Posted on 2023-05-28
398 Fluorescent protein lifetimes report increased local densities and phases of nuclear condensates during embryonic stem cell differentiation
Joron, K.; Viegas, J. O.; Haas-Neill, L.; Bier, S.; Drori, P.; Dvir, S.; Lim, P. S. L.; Rauscher, S.; Meshorer, E.; Lerner, E.
10.1101/2023.01.12.523769 — biophysics — Posted on 2023-05-28
401 Sequential Switching Through IgG1 is Redundant for Allergic Reactivity and Memory to Allergens
Koenig, J. F.; Wade-Vallance, A. K.; Jimenez-Saiz, R.; Bruton, K.; Gadkar, S.; Grydziuszko, E.; Walker, T.; Gordon, M. E.; Waserman, S.; Jordana, M.
10.1101/2023.05.27.542563 — immunology — Posted on 2023-05-28
405 Ocean-scale variation in migration schedules of a long-distance migratory seabird is fully compensated upon return to the breeding site
van Bemmelen, R. S. A.; Moe, B.; Schekkerman, H.; Hansen, S. A.; Snell, K. R. S.; Humphreys, E. M.; Mantyla, E.; Hallgrimsson, G. T.; Gilg, O.; Ehrich, D.; Calladine, J.; Hammer, S.; Harris, S. J.; Lang, J.; Vignisson, S. R.; Kolbeinsson, Y.; Nuotio, K.; Sillanpaa, M.; Sittler, B.; Sokolov, A.; Klaassen, R. H. G.; Phillips, R. A.; Tulp, I.
10.1101/2023.05.27.542544 — ecology — Posted on 2023-05-28
407 Targeting retrovirus-derived Rtl8a and 8b causes late onset obesity and neurodevelopmental defects
Fujioka, Y.; Shiura, H.; Ishii, M.; Ono, R.; Endo, T.; Kiyonari, H.; Hirate, Y.; Ito, H.; Kanai-Azuma, M.; Kohda, T.; Kaneko-Ishino, T.; Ishino, F.
10.1101/2023.05.28.542606 — molecular biology — Posted on 2023-05-28
408 No Wolbachia protection against Plasmodium falciparum infection in the major malaria mosquito Anopheles moucheti
Mouillaud, T.; Berger, A.; Buysse, M.; Rahola, N.; Daron, J.; Agbor, J.-P.; Nsango, S. N.; Neafsey, D. E.; Duron, O.; Ayala, D.
10.1101/2023.05.28.542560 — microbiology — Posted on 2023-05-28
409 α-Synuclein oligomers form by secondary nucleation
Xu, C. K.; Meisl, G.; Andrzejewska, E.; Krainer, G.; Dear, A. J.; Cruz, M. C.; Turi, S.; Jacquat, R.; Arter, W. E.; Vendruscolo, M.; Linse, S.; Knowles, T. P.
10.1101/2023.05.28.542651 — biophysics — Posted on 2023-05-28
412 False positive glycopeptide identification via in-FAIMS fragmentation
Rangel-Angarita, V.; Mahoney, K. E.; Kwon, C.; Sarker, R.; Lucas, T. M.; Malaker, S. A.
10.1101/2023.05.28.542648 — biochemistry — Posted on 2023-05-28
413 The Genetic Landscape of a Metabolic Interaction
Nguyen, T. N.; Ingle, C.; Thompson, S.; Reynolds, K. A.
10.1101/2023.05.28.542639 — biochemistry — Posted on 2023-05-28
414 Study of Glucometer Precision and Antimalarial Therapy Interference on Glucose Readings in Nigeria
Ugochukwu, E. J.; Mosanya, A. U.; Nweze, V. N.; Chukwu, M. I.; Ubaka, C. M.; Alawami, M.
10.1101/2023.05.28.542634 — biochemistry — Posted on 2023-05-28
418 A predatory gastrula leads to symbiosis-independent settlement in Aiptasia
Maegele, I.; Rupp, S.; Oezbek, S.; Guse, A.; Hambleton, E. A.; Holstein, T. W.
10.1101/2023.05.26.542442 — zoology — Posted on 2023-05-28
420 SOX7: Novel Autistic Gene Identified by Analysis of Multi-Omics Data
Gonzales, S.; Zhao, J. Z.; Choi, N. Y.; Acharya, P.; Jeong, S.; Lee, M.-Y.
10.1101/2023.05.26.542456 — bioinformatics — Posted on 2023-05-28
421 The developmental gene disco regulates diel-niche evolution in adult moths
Sondhi, Y.; Messcher, R. L.; Bellantuano, A. J.; Storer, C. G.; Cinel, S. D.; Godfrey, R. K.; Glass, D.; St. Laurent, R. A.; Hamilton, C. A.; Earl, C.; Brislawn, C. J.; Kitching, I. J.; Bybee, S. M.; Theobald, J. C.; Kawahara, A. Y.
10.1101/2023.05.28.542320 — evolutionary biology — Posted on 2023-05-28
422 The distribution of global tidal marshes from earth observation data
Worthington, T. A.; Spalding, M.; Landis, E.; Maxwell, T. L.; Navarro, A.; Smart, L. S.; Murray, N. J.
10.1101/2023.05.26.542433 — ecology — Posted on 2023-05-28
424 The histone lysine demethylase KDM5C fine-tunes gene expression to regulate dendritic cell heterogeneity and function
Guak, H.; Weiland, M. J.; VanderArk, A. R.; Zhai, L.; Lau, K.; Mabvakure, B.; Corrado, M.; Davidson, P.; Compton, S.; DeCamp, L.; Jones, R. M.; Nowinski, S.; Krawczyk, C. M.
10.1101/2023.05.28.542441 — immunology — Posted on 2023-05-28
425 Modeling Antigen-Specific T Cell Dynamics Following Hepatitis B Vaccination indicates differences between conventional and regulatory T cell dynamics
Besbassi, H.; Elias, G.; Souquette, A.; Meysman, P.; Jansens, H.; Laukens, K.; Van Damme, P.; Thomas, P.; Hens, N.; Beutels, P.; Ogunjimi, B.
10.1101/2023.05.27.542434 — immunology — Posted on 2023-05-28
427 Evidence for a competitive relationship between executive functions and statistical learning
Pedraza, F.; Farkas, B. C.; Vekony, T.; Haesebaert, F.; Phelipon, R.; Mihalecz, I.; Janacsek, K.; Anders, R.; Tillmann, B.; Plancher, G.; Nemeth, D.
10.1101/2023.01.19.524710 — neuroscience — Posted on 2023-05-28
428 Defying Gravity: WEEP promotes negative gravitropism in Prunus persica (peach) shoots and roots by establishing asymmetric auxin gradients
Kohler, A. R.; Scheil, A.; Hill, J. L.; Allen, J. R.; Al-Haddad, J. M.; Goeckeritz, C. Z.; Strader, L. C.; Telewski, F. W.; Hollender, C. A.
10.1101/2023.05.26.542472 — plant biology — Posted on 2023-05-28
429 Dilated cardiomyopathy variant R14del increases phospholamban pentamer stability, blunting dynamic regulation of cardiac calcium handling
Cleary, S. R.; Teng, A. C.; Deyawe Kongmeneck, A.; Fang, X.; Phillips, T. A.; Cho, E. E.; Kekenes-Huskey, P. M.; Gramolini, A. O.; Robia, S. L.
10.1101/2023.05.26.542463 — physiology — Posted on 2023-05-28
434 Balancing Memorization and Generalization in RNNsfor High Performance Brain-Machine Interfaces
Costello, J. T.; Temmar, H.; Cubillos, L. H.; Mender, M. J.; Wallace, D. M.; Willsey, M. S.; Patil, P. G.; Chestek, C. A.
10.1101/2023.05.28.542435 — bioengineering — Posted on 2023-05-28
435 Convergent evolution of noxious heat sensing by TRPA5, a novel class of heat sensor in Rhodnius prolixus
Lienard, M. A.; Baez-Nieto, D.; Tsai, C.-C.; Valencia-Montoya, W. A.; Werin, B.; Johanson, U.; Lassance, J.-M.; Pan, J. Q.; Yu, N.; Pierce, N. E.
10.1101/2023.05.26.542450 — evolutionary biology — Posted on 2023-05-28
436 Nutrient addition impacts grassland productivity responses to dry and wet climate extremes despite functional diversity loss
Chen, Q.; Wang, S.-P.; Seabloom, E. W.; Isbell, F.; Borer, E. T.; Bakker, J. D.; Bharath, s.; Roscher, C.; Peri, P. L.; Power, S. A.; Donohue, I.; Stevens, C.; Ebeling, A.; Nogueira, C.; Caldeira, M. C.; MacDougall, A.; Moore, J.; Bagchi, S.; Jentsch, A.; Tedder, M.; Kirkman, K.; Alberti, J.; Hautier, Y.
10.1101/2022.09.16.508233 — ecology — Posted on 2023-05-28
439 Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during chronic infection
Zheng, W.; Chang, I.-C.; Limberis, J.; Budzik, J. M.; Zha, B. S.; Howard, Z.; Chen, L.; Ernst, J. D.
10.1101/2023.01.19.524758 — immunology — Posted on 2023-05-28
440 Systemic Metabolic and Mitochondrial Defects in Rett Syndrome Models
Zlatic, S. A.; Werner, E.; Surapaneni, V.; Lee, C. E.; Gokhale, A.; Singleton, K.; Duong, D.; Crocker, A.; Gentile, K.; Middleton, F.; Dalloul, J. M.; Liu, W. L.-Y.; Patgiri, A.; Tarquinio, D.; Carpenter, R.; Faundez, V.
10.1101/2023.04.03.535431 — neuroscience — Posted on 2023-05-28
441 Mapping the Organization and Morphology of Calcitonin Gene-Related Peptide (CGRP)-IR Axons in the Whole Mouse Stomach
Ma, J.; Nguyen, D.; Madas, J.; Bizanti, A.; Mistareehi, A.; Kwiat, A. M.; Chen, J.; Lin, M.; Christie, R.; Hunter, P.; Heal, M.; Baldwin, S.; Tappan, S.; Furness, J. B.; Powley, T. L.; Cheng, Z. J.
10.1101/2023.05.23.541811 — neuroscience — Posted on 2023-05-28
442 Salt-inducible kinase inhibition promotes the adipocyte thermogenic program and adipose tissue browning
Shi, F.; de Fatima Silva, F.; Liu, D.; Patel, H. U.; Xu, J.; Zhang, W.; Turk, C.; Kruger, M.; Collins, S.
10.1101/2022.10.27.514130 — physiology — Posted on 2023-05-28
445 Does stress make males? An experiment on the role of glucocorticoids in anuran sex reversal
Bokony, V.; Kalina, C.; Ujhegyi, N.; Miko, Z.; Lefler, K. K.; Vili, N.; Gal, Z.; Gabor, C. R.; Hoffmann, O. I.
10.1101/2023.05.27.541969 — physiology — Posted on 2023-05-28
448 Droplet-based bisulfite sequencing for high-throughput profiling of single-cell DNA methylomes
Zhang, Q.; Ma, S.; Liu, Z.; Zhu, B.; Zhou, Z.; Li, G.; Meana, J. J.; Gonzalez-Maeso, J.; Lu, C.
10.1101/2023.05.26.542421 — genomics — Posted on 2023-05-28
449 Divergent evolution of sleep functions
Joyce, M.; Falconio, F. A.; Blackhurst, L.; Prieto-Godino, L. L.; French, A. S.; Gilestro, G. F.
10.1101/2023.05.27.541573 — evolutionary biology — Posted on 2023-05-28
453 Elevated sleep need in a stress-resilient Drosophila species
Yano, J.; Nave, C.; Larratt, K.; Honey, P.; Jingco, C.; Roberts, M.; Trotter, D.; He, X.; Elezi, G.; Whitelegge, J. P.; Wasserman, S.; Donlea, J. M.
10.1101/2023.05.27.542279 — neuroscience — Posted on 2023-05-28
454 Nitrogen source and Nod factor signaling map out the assemblies of Lotus japonicus root bacterial communities
Tao, K.; Jensen, I. T.; Zhang, S.; Villa-Rodriguez, E.; Blahovska, Z.; Salomonsen, C. L.; Martyn, A.; Bjorgvinsdottir, T. N.; Kelly, S.; Janss, L.; Glasius, M.; Waagepetersen, R.; Radutoiu, S.
10.1101/2023.05.27.542319 — plant biology — Posted on 2023-05-28
455 ADORE: A benchmark dataset for machine learning in ecotoxicology
Schuer, C.; Gasser, L.; Perez-Cruz, F.; Schirmer, K.; Baity-Jesi, M.
10.1101/2023.05.27.542160 — bioinformatics — Posted on 2023-05-28
457 EXTRACELLULAR PERINEXAL SEPARATION IS A PRINCIPAL DETERMINANT OF CARDIAC CONDUCTION
Adams, W. P.; Raisch, T. B.; Zhao, Y.; Davalos, R.; Barrett, S.; King, D. R.; Bain, C. B.; Colucci, K.; Blair, G. A.; Lozano, A. J.; Hanlon, A. L.; Veeraraghavan, R.; Wan, X.; Deschenes, I.; Smyth, J.; Hoeker, G. S.; Gourdie, R. G.; Poelzing, S.
10.1101/2023.05.25.542366 — biophysics — Posted on 2023-05-28
458 Fluorescent protein lifetimes report increased local densities and phases of nuclear condensates during embryonic stem cell differentiation
Joron, K.; Viegas, J. O.; Haas-Neill, L.; Bier, S.; Drori, P.; Dvir, S.; Lim, P. S. L.; Rauscher, S.; Meshorer, E.; Lerner, E.
10.1101/2023.01.12.523769 — biophysics — Posted on 2023-05-28
459 Reducing microtubule detyrosination improves heart function in HCM mice and human iPSC-engineered heart tissues
Pietsch, N.; Chen, C. Y.; Kupsch, S.; Bacmeister, L.; Geertz, B.; Herera-Rivero, M.; Voss, H.; Krämer, E.; Braren, I.; Westermann, D.; Schlüter, H.; Mearini, G.; Schlossarek, S.; van der Velden, J.; Caporizzo, M. A.; Lindner, D.; Prosser, B. L.; Carrier, L.
10.1101/2023.05.25.542365 — physiology — Posted on 2023-05-28
461 MISATO - Machine learning dataset of protein-ligand complexes for structure-based drug discovery
Siebenmorgen, T.; Menezes, F.; Benassou, S.; Merdivan, E.; Kesselheim, S.; Piraud, M.; Theis, F. J.; Sattler, M.; Popowicz, G. M.
10.1101/2023.05.24.542082 — bioinformatics — Posted on 2023-05-28
464 Intratumoral administration of recombinant murine interleukin-12 prevents tumor progression and bone invasion
Uchihashi, T.; Kasahara, S.; Inubushi, T.; Kurioka, K.; Sugauchi, A.; Miyagawa, K.; Kogo, M.; Tanaka, S.
10.1101/2023.05.26.542415 — cancer biology — Posted on 2023-05-27
465 FluoMALDI microscopy: matrix co-crystallization simultaneously enhances fluorescence and MALDI imaging
Yang, E.; Shen, X. E.; West-Foyle, H.; Brown, D. R.; Johnson, C. C.; Kim, J. H.; Roker, L. A.; Tressler, C. M.; Barman, I.; Kuo, S. C.; Glunde, K.
10.1101/2023.05.27.542340 — biochemistry — Posted on 2023-05-27
466 Pathogenic variants in CRX have distinct cis-regulatory effects on enhancers and silencers in photoreceptors
Shepherdson, J. L.; Friedman, R. Z.; Zheng, Y.; Sun, C.; Oh, I. Y.; Granas, D. M.; Cohen, B. A.; Chen, S.; White, M. A.
10.1101/2023.05.27.542576 — genomics — Posted on 2023-05-27
467 Association of an estrogen-sensitive Pax1-Col11a1-Mmp3 signaling axis with adolescent idiopathic scoliosis
Wise, C.; Yu, H.; Khanshour, A. M.; Ushiki, A.; Otomo, N.; Koike, Y.; Einarsdottir, E.; Fan, Y.; Antunes, L.; Kidane, Y. H.; Sheng, R.; Zhang, Y.; Pei, J.; Grishin, N. V.; Evers, B. M. V.; Cheung, J. P. Y.; Herring, J. A.; Terao, C.; Song, Y.-Q.; Gurnett, C.; Gerdhem, P.; Ikegawa, S.; Rios, J. J.; Ahituv, N.
10.1101/2023.05.26.542293 — genetics — Posted on 2023-05-27
468 Wnt4a is indispensable for genital duct elongation but not for gonadal sex differentiation in the medaka Oryzias latipes
Kanamori, A.; Kitani, R.; Oota, A.; Hirano, K.; Myosho, T.; Kobayashi, T.; Kawamura, K.; Kato, N.; Ansai, S.; Kinoshita, M.
10.1101/2023.05.26.542371 — developmental biology — Posted on 2023-05-27
470 A new MAPK13-guided inhibitor for respiratory inflammation and mucus production
Keeler, S. P.; Wu, K.; Zhang, Y.; Mao, D.; Li, M.; Iberg, C. A.; Austin, S. R.; Glaser, S. A.; Yantis, J.; Podgorny, S.; Brody, S. L.; Chartock, J. R.; Han, Z.; Byers, D. E.; Romero, A. G.; Holtzman, M. J.
10.1101/2023.05.26.542451 — immunology — Posted on 2023-05-27
471 BIG participates in the Arg/N-degron pathways and the hypoxia response in Arabidopsis thaliana.
Zhang, H.; Rundle, C.; Winter, N.; Miricescu, A.; Mooney, B. C.; Bachmair, A.; Graciet, E.; Theodoulou, F. L.
10.1101/2023.05.26.542459 — plant biology — Posted on 2023-05-27
472 ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion.
Menolfi, D.; Lee, B. J.; Zhang, H.; Jiang, W.; Brown, N. E.; Wang, Y.; Zhao, J.; Holmes, A.; Gershik, S.; Rabadan, R.; Kim, B.; Zha, S.
10.1101/2023.05.26.542515 — genetics — Posted on 2023-05-27
473 Cancer phylogenetic tree inference at scale from 1000s of single cell genomes
Salehi, S.; Dorri, F.; Chern, K.; Kabeer, F.; Rusk, N.; Funnell, T.; Williams, M. J.; Lai, D.; Andronescu, M.; Campbell, K. R.; McPherson, A.; Aparicio, S.; Roth, A.; Shah, S. P.; Bouchard-Cote, A.
10.1101/2020.05.06.058180 — bioinformatics — Posted on 2023-05-27
476 Gene editing without ex vivo culture evades genotoxicity in human hematopoietic stem cells
Zeng, J.; Nguyen, M. A.; Liu, P.; Ferreira da Silva, L.; Lin, L. Y.; Justus, D. G.; Petri, K.; Clement, K.; Porter, S. N.; Verma, A.; Neri, N. R.; Rosanwo, T.; Ciuculescu, M.-F.; Abriss, D.; Mintzer, E.; Maitland, S. A.; Demirci, S.; Tisdale, J. F.; Williams, D. A.; Zhu, L. J.; Pruett-Miller, S. M.; Pinello, L.; Joung, J. K.; Pattanayak, V.; Manis, J. P.; Armant, M.; Pellin, D.; Brendel, C.; Wolfe, S. A.; Bauer, D. E.
10.1101/2023.05.27.542323 — genetics — Posted on 2023-05-27
477 Symbiotic bacteria, immune-like sentinel cells, and the response to pathogens in a social amoeba
Scott, T. J.; Larsen, T. J.; Brock, D. A.; Uhm, S. Y. S.; Queller, D. C.; Strassmann, J. E.
10.1101/2023.05.27.542568 — ecology — Posted on 2023-05-27
478 CD5L is a canonical component of circulatory IgM
Oskam, N.; den Boer, M. A.; Lukassen, M. V.; Ooijevaar-de Heer, P.; Veth, T. S.; van Mierlo, G.; Lai, S.-H.; Derksen, N. I.; Yin, V. C.; Streutker, M.; Franc, V.; Siborova, M.; Damen, M.; Kos, D.; Barendregt, A.; Bondt, A.; van Goudoever, J. B.; Haas, C. J.; Aerts, P. C.; Muts, R. M.; Rooijakkers, S. H.; Vidarsson, G.; Rispens, T.; Heck, A. J.
10.1101/2023.05.27.542462 — molecular biology — Posted on 2023-05-27
482 SARS-CoV-2 lineage assignments using phylogenetic placement/UShER are superior to pangoLEARN machine learning method
de Bernardi Schneider, A.; Su, M.; Hinrichs, A. S.; Wang, J.; Amin, H.; Bell, J.; Wadford, D. A.; O'Toole, A.; Scher, E.; Perry, M. D.; Turakhia, Y.; De Maio, N.; Hughes, S.; Corbett-Detig, R.
10.1101/2023.05.26.542489 — bioinformatics — Posted on 2023-05-27
486 Improved imaging and preservation of lysosome dynamics using silver nanoparticle-enhanced fluorescence
Soha, S. A.; Santhireswaran, A.; Huq, S.; Casimir-Powell, J.; Jenkins, N.; Hodgson, G. K.; Sugiyama, M.; Antonescu, C. N.; Impellizzeri, S.; Botelho, R. J.
10.1101/2022.04.26.489585 — cell biology — Posted on 2023-05-27
492 SpliceMutr enables pan-cancer analysis of splicing-derived neoantigen burden in tumors
Palmer, T.; Kessler, M. D.; Shao, X. M.; Balan, A.; Yarchoan, M.; Zaidi, N.; Lopez-Vidal, T. Y.; Saeed, A.; Gore, J.; Azad, N.; Jaffee, E.; Favorov, A. V.; Anagnostou, V.; Karchin, R.; Gaykalova, D.; Danilova, L.; Fertig, E. J.
10.1101/2023.05.26.542165 — cancer biology — Posted on 2023-05-27
494 Age- and caste-independent piRNAs in the germline and miRNA profiles linked to caste and fecundity in the ant Temnothorax rugatulus
Seistrup, A.-S.; Choppin, M.; Govind, S.; Feldmeyer, B.; Kever, M.; Karaulanov, E.; Seguret, A.; Karunanithi, S.; Almeida, M. V.; Ketting, R. F.; Foitzik, S.
10.1101/2023.05.21.541611 — ecology — Posted on 2023-05-27
495 The landscape of drug sensitivity and resistance in sarcoma
Al Shihabi, A.; Tebon, P. J.; Nguyen, H. T. L.; Chantharasamee, J.; Sartini, S.; Davarifar, A.; Jensen, A. Y.; Diaz-Infante, M.; Cox, H.; Enrique-Gonzalez, A.; Swearingen, S.; Tavanaie, N.; Dry, S.; Singh, A.; Chmielowski, B.; Crompton, J. G.; Kalbasi, A.; Eilber, F. C.; Hornicek, F.; Bernthal, N.; Nelson, S. D.; Boutros, P. C.; Federman, N.; Yanagawa, J.; Soragni, A.
10.1101/2023.05.25.542375 — cancer biology — Posted on 2023-05-26
497 SpliceMutr enables pan-cancer analysis of splicing-derived neoantigen burden in tumors
Palmer, T.; Kessler, M. D.; Shao, X. M.; Balan, A.; Yarchoan, M.; Zaidi, N.; Lopez-Vidal, T. Y.; Saeed, A.; Gore, J.; Azad, N.; Favorov, A. V.; Anagnostou, V.; Karchin, R.; Gaykalova, D.; Danilova, L.; Fertig, E. J.
10.1101/2023.05.26.542165 — cancer biology — Posted on 2023-05-26
499 Tumor-specific neutrophils originating from meninges promote glioblastoma
Zhao, J.; Wu, D.; Liu, J.; Zhang, Y.; Cao, P.; Li, C.; Wu, S.; Li, M.; Cui, Y.; Sun, Y.; Yang, E.; Ji, N.; Yang, J.; Chen, J.
10.1101/2023.05.23.542010 — cancer biology — Posted on 2023-05-26
505 Polarized Mechanosensitive Signaling Domains Protect Arterial Endothelial Cells Against Inflammation
Hong, S.-G.; Ashby, J. W.; Kennelly, J. P.; Wu, M.; Chattopadhyay, E.; Foreman, R.; Tontonoz, P.; Turowski, P.; Gallagher-Jones, M.; Mack, J. J.
10.1101/2023.05.26.542500 — cell biology — Posted on 2023-05-26
506 Syntenin and CD63 Promote Exosome Biogenesis from the Plasma Membrane by Blocking Cargo Endocytosis
Ai, Y.; Guo, C.; Garcia-Contreras, M.; Sanchez, L. S.; Saftics, A.; Shodubi, O.; Raghunandan, S.; Xu, J.; Tsai, S.-J.; Dong, Y.; Li, R.; Jovanovic-Talisman, T.; Gould, S.
10.1101/2023.05.26.542409 — cell biology — Posted on 2023-05-27
509 Multimodal gradients of human basal forebrain connectivity
Chakraborty, S.; Haast, R. A.; Kanel, P.; Khan, A. R.; Schmitz, T. W.
10.1101/2023.05.26.541324 — neuroscience — Posted on 2023-05-26
510 Mapping memories: pulse-chase labeling reveals AMPA receptor dynamics during memory formation
Kim, D.; Park, P.; Li, X. T.; Wong-Campos, J. D.; Tian, H.; Grimm, J. B.; Lavis, L.; Cohen, A. E.
10.1101/2023.05.26.541296 — neuroscience — Posted on 2023-05-26
516 Single cell spatial analysis and biomarker discovery in Hodgkin lymphoma
Xu, A. M.; Jiang, A. M.; Aoki, T.; Gamboa, A.; Chong, L.; Colombo, A. R.; Yin, Y.; Lownik, J.; Takata, K.; Hav, M.; Steidl, C.; Merchant, A.
10.1101/2023.05.24.542195 — cancer biology — Posted on 2023-05-26
518 Changes in Active Site Loop Conformation Relate to the Transition toward a Novel Enzymatic Activity
Jacquet, P.; Billot, R.; Shimon, A.; Hoekstra, N.; Bergonzi, C.; Jenks, A.; Chabriere, E.; Daude, D.; Elias, M.
10.1101/2023.05.22.541809 — biochemistry — Posted on 2023-05-26
519 Cross-species transcriptomic analysis identifies mitochondrial dysregulation as a functional consequence of the schizophrenia-associated 3q29 deletion
Purcell, R. H.; Sefik, E.; Werner, E.; King, A. T.; Mosley, T. J.; Merritt-Garza, M. E.; Chopra, P.; McEachin, Z. T.; Karne, S.; Raj, N.; Vaglio, B. J.; Sullivan, D.; Firestein, B. L.; Tilahun, K.; Robinette, M. I.; Warren, S. T.; Wen, Z.; Faundez, V.; Sloan, S. A.; Bassell, G. J.; Mulle, J. G.
10.1101/2023.01.27.525748 — genomics — Posted on 2023-05-26
523 ABI1 regulates transcriptional activity of Androgen Receptor by novel DNA and AR binding mechanism
Porter, B. A.; Li, X.; Arya, N.; Zhang, F.; Kung, S. H. Y.; Fazli, L.; Zarni Oo, H.; Li, Y.; Marincin, K.; Kukkonen, K.; Urhonen, H.; Ortiz, M. A.; Kemraj, A. P.; Corey, E.; Dong, X.; Kuznetsov, V. A.; Nykter, M.; Gleave, M. E.; Bratslavsky, G.; Urbanucci, A.; Frueh, D.; Bah, A.; Kotula, L.
10.1101/2023.05.26.542350 — cancer biology — Posted on 2023-05-26
524 SIX4 Controls STING Expression Enhancing anti-PD-1 Efficacy
Liang, B.; Zhang, E. H.; Ye, Z.; Storts, H.; Jin, W.; Zheng, X.; Zaleski, O.; Xing, X.; Wang, J. J.
10.1101/2023.05.26.542458 — cancer biology — Posted on 2023-05-26
525 Newly repopulated spinal cord microglia exhibit a unique transcriptome and correlate with pain resolution
Donovan, L. J.; Bridges, C. M.; Nippert, A. R.; Wang, M.; Wu, S.; Forman, T. E.; Haight, E. S.; Huck, N. A.; Bond, S. F.; Jordan, C. E.; Gardner, A. S.; Nair, R. V.; Tawfik, V. L.
10.1101/2022.12.20.521295 — neuroscience — Posted on 2023-05-26
530 Near-perfect precise on-target editing of human hematopoietic stem and progenitor cells
Cloarec-Ung, F.-M.; Beaulieu, J.; Suthananthan, A.; Lehnertz, B.; Sauvageau, G.; Sheppard, H. M.; Knapp, D. J.
10.1101/2023.05.26.542436 — bioengineering — Posted on 2023-05-26
531 Self-Assembly of a Repeatable DNA Nanohinge System Supporting Higher Order Structure Formation
Law, M.; Sushams, C.; Mackay, D.; Nguyen, S.; Nicholas, R.; Tsai, M. R. G.; Rajkumar, E.; Inaba, F.; Maheden, K.; Abdi, I.; Ho, J. C. H.; Kieft, B.; Hallam, S. J.
10.1101/2023.05.26.542516 — bioengineering — Posted on 2023-05-26
532 Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo
Yamada, K.; Hariharan, V. N.; Caiazzi, J.; Miller, R.; Ferguson, C.; Sapp, E.; Fakih, H.; Tan, Q.; Yamada, N.; Furgal, R.; Paquette, J.; Bramato, B.; McHugh, N.; Summer, A.; Lochmann, C.; Godinho, B.; Hildebrand, S.; Echeverria, D.; Hassler, M.; Alterman, J.; DiFiglia, M.; Aronin, N.; Khvorova, A.
10.1101/2023.05.26.542506 — biochemistry — Posted on 2023-05-26
533 Tet-dependent 5-hydroxymethyl-Cytosine modification of mRNA regulates axon guidance genes in Drosophila
Singh, B. N.; Tran, H.; Kramer, J.; Kirichenko, E.; Changela, N.; Wang, F.; Feng, Y.; Kumar, D.; Tu, M.; Lan, J.; Bizet, M.; Fuks, F.; Steward, R.
10.1101/2023.01.03.522592 — genomics — Posted on 2023-05-26
534 The Tgf-β family member Gdf6Y determines the male sex in Nothobranchius furzeri by suppressing oogenesis-inducing genes
Richter, A.; Mörl, H.; Thielemann, M.; Kleemann, M.; Geissen, R.; Schwarz, R.; Albertz, C.; Koch, P.; Petzold, A.; Groth, M.; Hartmann, N.; Herpin, A.; Englert, C.
10.1101/2023.05.26.542338 — molecular biology — Posted on 2023-05-26
535 TPR domain assigns versatility of BcTir/Tpr system against viral infection
Liu, Y.; Zhang, C.; Khudaverdyan, N.; Wang, J.; Zhang, L.; Golovko, M.; Golovko, S.; Guo, A.; Song, J.; Wu, M.; Combs, C.
10.1101/2023.05.26.542521 — microbiology — Posted on 2023-05-26
536 Variational Log-Gaussian Point-Process Methods for Grid Cells
Rule, M. E.; Vayalambrone, P. C.; Krstulovic, M.; Bauza, M.; Krupic, J.; O'Leary, T.
10.1101/2023.03.18.533177 — neuroscience — Posted on 2023-05-26
538 Dilated cardiomyopathy variant R14del increases phospholamban pentamer stability, blunting dynamic regulation of cardiac calcium handling
Cleary, S. R.; Teng, A. C.; Deyawe Kongmeneck, A.; Fang, X.; Phillips, T. A.; Cho, E. E.; Kekenes-Huskey, P. M.; Gramolini, A. O.; Robia, S. L.
10.1101/2023.05.26.542463 — physiology — Posted on 2023-05-26
540 cAMP binding to closed pacemaker ion channels is cooperative
Kuschke, S.; Thon, S.; Schwabe, T.; Benndorf, K.; Schmauder, R.
10.1101/2023.04.18.537331 — biophysics — Posted on 2023-05-26
543 Protein-mediated genome folding allosterically enhances site-specific integration of foreign DNA into CRISPRs
Santiago-Frangos, A.; Henriques, W. S.; Wiegand, T.; Gauvin, C. C.; Buyukyoruk, M.; Graham, A. B.; Wilkinson, R. A.; Triem, L.; Neselu, K.; Eng, E. T.; Lander, G. C.; Wiedenheft, B.
10.1101/2023.05.26.542337 — biochemistry — Posted on 2023-05-26
545 Transcriptomic landscape of posterior regeneration in the annelid Platynereis dumerilii
Pare, L.; Bideau, L.; Baduel, L.; Dalle, C.; Benchouaia, M.; Schneider, S. Q.; Laplane, L.; Clement, Y.; Vervoort, M.; Gazave, E.
10.1101/2023.05.26.542455 — genomics — Posted on 2023-05-26
549 Assessing the role of trypsin in quantitative plasma- and single-cell proteomics towards clinical application
Woessmann, J.; Petrosius, V.; Uresin, N.; Kotol, D.; Aragon-Fernandez, P.; Hober, A.; auf dem Keller, U.; Edfors, F.; Schoof, E. M.
10.1101/2023.05.26.542422 — molecular biology — Posted on 2023-05-26
550 KMT2C knockout generates ASD-like behaviors in mice.
Brauer, B.; Merino-Veliz, N.; Ahumada-Marchant, C.; Arriagada, G.; Bustos, F. J.
10.1101/2023.05.26.542423 — molecular biology — Posted on 2023-05-26
551 Viral modulation of type II interferon increases T cell adhesion and virus spread
Juergens, C.; Ssebyatika, G.; Beyer, S.; Plueckebaum, N.; Kropp, K.; Gonzalez-Motos, V.; Ritter, B.; Boening, H.; Nikolouli, E.; Kinchington, P. R.; Lachmann, N.; Depledge, D.; Krey, T.; Viejo-Borbolla, A.
10.1101/2023.05.26.542397 — microbiology — Posted on 2023-05-26
552 Sorgoleone degradation by sorghum-associated bacteria; an opportunity for enforcing plant growth promotion
Oda, Y.; Elmore, J. R.; Nelson, W. C.; Wilson, A.; Farris, Y.; Shrestha, R.; Garcia, C. F.; Pettinga, D.; Ogden, A. J.; Baldino, H.; Alexander, W. G.; Deutschbauer, A.; Hurtado, C. V.; McDermott, J. E.; Guss, A. M.; Coleman-Derr, D.; McClure, R.; Harwood, C. S.; Egbert, R.
10.1101/2023.05.26.542311 — microbiology — Posted on 2023-05-26
553 Trypanosoma brucei bloodstream form mitochondrion is capable of ATP production by substrate phoshorylation
Taleva, G.; Husova, M.; Panicucci, B.; Hierro-Yap, C.; Pineda, E.; Biran, M.; Moos, M.; Simek, P.; Bringaud, F.; Zikova, A.
10.1101/2023.05.26.542429 — microbiology — Posted on 2023-05-26
554 Metabolic disruption impacts tick fitness and microbial relationships
Samaddar, S.; O'Neal, A. J.; Marnin, L.; Rolandelli, A.; Singh, N.; Wang, X.; Butler, L. R.; Rangghran, P.; Laukaitis, H. J.; Cabrera Paz, F. E.; Fiskum, G. M.; Polster, B. M.; Pedra, J. H.
10.1101/2023.05.26.542501 — microbiology — Posted on 2023-05-26
555 Intra-V1 functional networks predict observed stimuli
Ontivero-Ortega, M.; Iglesias-Fuster, J.; Perez-Hidalgo, J.; Marinazzo, D.; Valdes-Sosa, M. J.; Valdes-Sosa, P. A.
10.1101/2022.10.20.513108 — neuroscience — Posted on 2023-05-26
556 Tau seeding and spreading in vivo is supported by both AD-derived fibrillar and oligomeric tau
Mate de Gerando, A.; Welikovitch, L. A.; Khasnavis, A.; Commins, C.; Glynn, C.; Chun, J. E.; Perbet, R.; Hyman, B. T.
10.1101/2023.03.28.534418 — neuroscience — Posted on 2023-05-26
557 Mouse models of SYNGAP1-related intellectual disability
Araki, Y.; Gerber, E. E.; Rajkovich, K. E.; Hong, I.; Johnson, R. C.; Lee, H.-K.; Kirkwood, A.; Huganir, R. L.
10.1101/2023.05.25.542312 — neuroscience — Posted on 2023-05-26
561 splicekit: a comprehensive toolkit for splicing analysis from short-read RNA-seq
Rot, G.; Wehling, A.; Schmucki, R.; Berntenis, N.; Zhang, J. D.; Ebeling, M.
10.1101/2023.05.25.542256 — bioinformatics — Posted on 2023-05-26
574 MINI-AC: Inference of plant gene regulatory networks using bulk or single-cell accessible chromatin profiles
Manosalva Perez, N.; Ferrari, C.; Engelhorn, J.; Depuydt, T.; Nelissen, H.; Hartwig, T.; Vandepoele, K.
10.1101/2023.05.26.542269 — bioinformatics — Posted on 2023-05-26
576 Electrostatically regulated active site assembly governs reactivity in non-heme iron halogenases
Smithwick, E. R.; Wilson, R. H.; Chatterjee, S.; Pu, Y.; Dalluge, J. J.; Rama Damodaran, A.; Bhagi-Damodaran, A.
10.1101/2023.05.25.542349 — biochemistry — Posted on 2023-05-26
577 What can New Zealand bats tell us about Coronaviruses?
Tortosa, P.; McInnes, K.; O'Donnell, C. F. J.; Pryde, M.; Gomard, Y.; Lebarbenchon, C.; Poulin, R.
10.1101/2023.05.26.542035 — ecology — Posted on 2023-05-26
580 Mitochondrial calcium signaling mediated transcriptional regulation of keratin filaments is a critical determinant of melanogenesis
Tanwar, J.; Ahuja, K.; Sharma, A.; Sehgal, P.; Ranjan, G.; Sultan, F.; Priya, A.; Venkatesan, M.; Yenamandra, V. K.; Singh, A. K.; Madesh, M.; Sivasubbu, S.; Motiani, R. K.
10.1101/2023.05.26.542250 — cell biology — Posted on 2023-05-26
581 m6A mRNA Methylation in Brown Adipose Tissue Regulates Systemic Insulin Sensitivity via an Inter-Organ Prostaglandin Signaling Axis
Xiao, L.; De Jesus, D. F.; Ju, C.-W.; Wei, J.-B.; Hu, J.; DiStefano-Forti, A.; Tsuji, T.; Cero, C.; Mannisto, V.; Manninen, S. M.; Wei, S.-Y.; Ijaduola, O.; Blueher, M.; Cypess, A. M.; Pihlajamaki, J.; Tseng, Y.-H.; He, C.; Kulkarni, R. N.
10.1101/2023.05.26.542169 — cell biology — Posted on 2023-05-26
582 Histone lactylation antagonizes senescence and skeletal muscle aging via facilitating gene expression reprogramming
Zhang, X.; Meng, F.; Lyu, W.; He, J.; Wei, R.; Du, Z.; Zhang, C.; Guan, Y.; Huang, X.; Lyu, G.; Tian, X.-L.; Zhang, L.; Tao, W.
10.1101/2023.05.26.542348 — cell biology — Posted on 2023-05-26
591 Mapping oak wilt disease using phenological observations from space
Guzman Q., J. A.; Pinto-Ledezma, J. N.; Frantz, D.; Townsend, P. A.; Juzwik, J.; Cavender-Bares, J.
10.1101/2023.05.25.542318 — ecology — Posted on 2023-05-26
592 GTPBP8 is required for mitoribosomal biogenesis and mitochondrial translation
Wang, L.; Hilander, T.; Liu, X.; Tsang, H.; Eriksson, O.; Jackson, C. B.; Varjosalo, M.; Zhao, H.
10.1101/2023.05.26.542385 — cell biology — Posted on 2023-05-26
594 DNA replication is not a limiting factor for the rapid growth of Vibrio natriegens
Ramming, L.; Stukenberg, D.; Sanchez Olmos, M. d. C.; Becker, A.; Schindler, D.
10.1101/2023.05.26.541695 — microbiology — Posted on 2023-05-26
595 Multi-omic Profiling Reveals Early Immunological Indicators for Identifying COVID-19 Progressors
Drake, K. A.; Talantov, D.; Tong, G.; Lin, J. T.; Verheijden, S.; Katz, S.; Leung, J. M.; Yuen, B.; Krishna, V.; Wu, M. J.; Sutherland, A.; Short, S.; Kheradpour, P.; Mumbach, M. R.; Franz, K. M.; Trifonov, V.; Lucas, M. V.; Merson, J.; Kim, C. C.; The PRESCO Study Group,
10.1101/2023.05.25.542297 — immunology — Posted on 2023-05-26
596 Serotonergic reinforcement of a complete swallowing circuit
Schoofs, A.; Miroschnikow, A.; Schlegel, P.; Zinke, I.; Schneider-Mizell, C. M.; Cardona, A. M.; Pankratz, M. J.
10.1101/2023.05.26.542464 — neuroscience — Posted on 2023-05-26
598 Prominent elevation of extracellular matrix molecules in intracerebral hemorrhage
Li, H.; Ghorbanigazar, S.; Zhang, R.; Ebacher, V.; Stephenson, E. L.; Yong, V. W.; Xue, M.
10.1101/2023.05.26.542446 — neuroscience — Posted on 2023-05-26
599 Cholecystokinin is the follicle-stimulating hormone (FSH)-releasing hormone
Uehara, S. K.; Nishiike, Y.; Maeda, K.; Karigo, T.; Kuraku, S.; Okubo, K.; Kanda, S.
10.1101/2023.05.26.542428 — neuroscience — Posted on 2023-05-26
600 An intra-oral flavor discrimination task in freely moving mice
Shiotani, K.; Tanisumi, Y.; Osako, Y.; Murata, K.; Hirokawa, J.; Sakurai, Y.; Manabe, H.
10.1101/2023.05.26.542382 — neuroscience — Posted on 2023-05-26
609 Voltage dynamics of dendritic integration and back-propagation in vivo
Wong-Campos, J. D.; Park, P.; Davis, H. C.; Qi, Y.; Tian, H.; Itkis, D. G.; Kim, D.; Grimm, J. B.; Plutkis, S. E.; Lavis, L.; Cohen, A. E.
10.1101/2023.05.25.542363 — neuroscience — Posted on 2023-05-26
610 Contrasting synaptic roles of MDGA1 and MDGA2
Bemben, M. A.; Sandoval, M. A.; Le, A. A.; Won, S.; Chau, V. N.; Lauterborn, J. C.; Incontro, S.; Li, K. H.; Burlingame, A. L.; Roche, K. W.; Gall, C. M.; Nicoll, R. A.; Diaz-Alonso, J.
10.1101/2023.05.25.542333 — neuroscience — Posted on 2023-05-26
611 Intact reinforcement learning in healthy ageing
Lin, W.-H.; Clarke, A.; Pilz, K. S.; Herzog, M. H.; Kunchulia, M.
10.1101/2023.05.25.542104 — neuroscience — Posted on 2023-05-26
615 Deep Learning models for retinal cell classification
Kostalkowski, M.; Kordecka, K.; Placzkiewicz, J.; Posluszny, A.; Foik, A.
10.1101/2023.05.26.542384 — neuroscience — Posted on 2023-05-26
617 Development of a genetically-encoded sensor for probing endogenous nociceptin opioid peptide release
Zhou, X.; Stine, C.; Prada, P. O.; Fusca, D.; Assoumou, K.; Dernic, J.; Bhat, M. A.; Achanta, A. S.; Johnson, J. C.; Jadhav, S.; Bader, C. A.; Steuernagel, L.; Ravotto, L.; Benke, D.; Weber, B.; Stoeber, M.; Kloppenburg, P.; Bruening, J. C.; Bruchas, M. R.; Patriarchi, T.
10.1101/2023.05.26.542102 — neuroscience — Posted on 2023-05-26
619 The Crucial Role of CTCF in Mitotic Progression during Early Development of Sea Urchin.
Watanabe, K.; Fujita, M.; Okamoto, K.; Yoshioka, H.; Moriwaki, M.; Tagashira, H.; Yamamoto, T.; Sakamoto, N.
10.1101/2023.05.26.542381 — developmental biology — Posted on 2023-05-26
621 Microbes with higher metabolic independence are enriched in human gut microbiomes under stress
Veseli, I.; Chen, Y. T.; Schechter, M. S.; Vanni, C.; Fogarty, E. C.; Watson, A. R.; Jabri, B. A.; Blekhman, R.; Willis, A. D.; Yu, M. K.; Fernandez-Guerra, A.; Fussel, J.; Eren, A. M.
10.1101/2023.05.10.540289 — microbiology — Posted on 2023-05-26
622 Age, sex, and social environmental effects on immune cell composition in a free-ranging non-human primate.
Rosado, M. R. S.; Marzan-Rivera, N.; Watowich, M. M.; Negron-Del Valle, A. D.; Pantoja, P.; Pavez-Fox, M. A.; Siracusa, E. R.; Negron-Del Valle, J. E.; Phillips, D.; Ruiz-Lambides, A.; Cayo Biobank Research Unit, ; Martinez, M. I.; Montague, M. J.; Platt, M. L.; Higham, J. P.; Brent, L. J. N.; Sariol, C. A.; Snyder-Mackler, N.
10.1101/2021.12.06.471383 — immunology — Posted on 2023-05-26
625 Identification of post-transcriptional modifications in nucleic acid sequences using purpose-designed molecular beacons
Sahu, P.; Pereira, G.; Wang, J.; Dokholyan, N.; Szeliski, K.; tran, V.; Korneck, M.; Tigges, J.; Jones, J.; Ghiran, I.
10.1101/2023.05.25.542360 — molecular biology — Posted on 2023-05-26
627 Hijacking of internal calcium dynamics by intracellularly residing rhodopsins
Eria-Oliveira, A.-S.; Folacci, M.; Chassot, A. A.; Fedou, S.; Theze, N.; Zabelskii, D.; Alekseev, A.; Bamberg, E.; Gordeliy, V.; Sandoz, G.; Vivaudou, M.
10.1101/2023.05.25.542240 — physiology — Posted on 2023-05-26
628 Actomyosin remodeling regulates biomineral formation, growth and morphology during eukaryote skeletogenesis
Hijaze, E.; Gildor, T.; Seidel, R.; Layous, M.; Winter, M.; Bertinetti, L.; Politi, Y.; de-Leon, S. B.-T.
10.1101/2022.12.21.521381 — developmental biology — Posted on 2023-05-26
630 A simple mechanism for integration of quorum sensing and cAMP signalling in V. cholerae
Walker, L.; Haycocks, J. R.; van Kessel, J.; Dalia, T. N.; Dalia, A. B.; Grainger, D. C.
10.1101/2023.02.08.527633 — microbiology — Posted on 2023-05-26
633 MDM2 acts as a timer reporting the length of mitosis
Fulcher, L.; Sobajima, T.; Gibbs-Seymour, I.; Barr, F. A.
10.1101/2023.05.26.542398 — cell biology — Posted on 2023-05-26
634 Population context drives cell-to-cell variability in interferon response in epithelial cells
Metz-Zumaran, C.; Doldan, P.; Muraca, F.; Keser, Y.; Lukas, P.; Kuropka, B.; Küchenhoff, L.; Rastgou Talemi, S.; Hoefer, T.; Freund, C.; Cavalcanti-Adam, E. A.; Graw, F.; Stanifer, M. L.; Boulant, S.
10.1101/2023.05.22.541682 — immunology — Posted on 2023-05-26
635 A Multi-Epitope/CXCL11 Prime/Pull Coronavirus Mucosal Vaccine Boosts the Frequency and the Function of Lung-Resident CD4+ and CD8+ Memory T Cells and Protects Against COVID-19-like Symptoms and Death Caused by SARS-CoV-2 infection
Zayou, L.; Prakash, S.; Dhanushkodi, N. R.; Quadiri, A.; Ibraim, I. C.; Singer, M.; Salem, A.; Shaik, A. M.; Suzer, B.; Chilukuri, A.; Tran, J.; Nguyen, P. C.; Sun, M.; Hormi-Carver, K. K.; Belmouden, A.; Vahed, H.; Ulmer, J. B.; BENMOHAMED, L.
10.1101/2023.05.23.542024 — immunology — Posted on 2023-05-26
636 Generation and therapeutic efficacy of the novel Fc-modified cross-neutralizing human monoclonal antibodies against dengue virus
Injampa, S.; Benjathummarak, S.; Keadsanti, S.; Puangmanee, W.; Yamanaka, A.; Sasaki, T.; Ikuta, K.; Ramasoota, P.; Pitaksajjakul, P.
10.1101/2023.05.25.542225 — immunology — Posted on 2023-05-26
638 Systems analysis of miR-199a/b-5p and multiple miR-199a/b-5p targets during chondrogenesis
Patel, K.; Barter, M. J.; Soul, J.; Clark, P.; Proctor, C. J.; Clark, I. M.; Young, D.; Shanley, D. P.
10.1101/2023.03.31.535081 — systems biology — Posted on 2023-05-26
641 The sequestration of miR-642a-3p by a complex formed by HIV-1 Gag and human Dicer increases AFF4 expression and viral production
Alpuche-Lazcano, S. P.; Dunkley, O. R.; Scarborough, R. J.; Daniels, S. M.; Daher, A.; Truchi, M.; Estable, M. C.; Mari, B.; J. Mouland, A.; Gatignol, A.
10.1101/2023.05.24.542197 — microbiology — Posted on 2023-05-26
645 IntAct: a non-disruptive internal tagging strategy to study actin isoform organization and function
van Zwam, M. C.; Dhar, A.; Bosman, W.; van Straaten, W.; Weijers, S.; Seta, E.; Joosten, B.; Palani, S.; van den Dries, K.
10.1101/2021.10.25.465733 — cell biology — Posted on 2023-05-26
647 IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic Trypanosoma brucei infection
Sinton, M. C.; Chandrasegaran, P.; Capewell, P.; Cooper, A.; Girard, A.; Ogunsola, J.; Perona-Wright, G.; Ngoyi, D.; Kuispond, N.; BUCHETON, B.; Camara, M.; Kajimura, S.; Benezech, C.; MacLeod, A.; Quintana Alcala, J. F.
10.1101/2022.09.23.509158 — immunology — Posted on 2023-05-26
648 Two human brain systems micro-structurally associated with obesity
Kitzbichler, M. G.; Martins, D. G.; Bethlehem, R. A. I.; Dear, R.; Romero-Garcia, R.; Warrier, V.; Seidlitz, J.; Dipasquale, O.; Turkheimer, F. E.; Cercignani, M.; Bullmore, E. T.; Harrison, N. A.
10.1101/2022.11.25.517981 — neuroscience — Posted on 2023-05-26
649 Injury risk functions for the four primary knee ligaments
Nusia, J.; Xu, J. C.; Knälmann, J.; Sjöblom, R.; Kleiven, S.
10.1101/2021.07.30.454445 — bioengineering — Posted on 2023-05-26
650 Beyond variance: simple random distributions are not a good proxy for intraspecific variability in systems with environmental structure
Girard-Tercieux, C.; Vieilledent, G.; Clark, A. T.; Clark, J. S.; Courbaud, B.; Fortunel, C.; Kunstler, G.; Pelissier, R.; Rueger, N.; Marechaux, I.
10.1101/2022.08.06.503032 — ecology — Posted on 2023-05-26
652 Goal-directed vocal planning in a songbird
Zai, A. T.; Stepien, A. E.; Giret, N.; Hahnloser, R. H. R.
10.1101/2022.09.27.509747 — neuroscience — Posted on 2023-05-26
653 Two neuronal models of TDP-43 proteinopathy display reduced axonal translation, increased oxidative stress, and defective exocytosis.
Pisciottani, A.; Croci, L.; Lauria, F.; Marullo, C.; Savino, E.; Ambrosi, A.; Podini, P.; Marchioretto, M.; Casoni, F.; Cremona, O.; Taverna, S.; Quattrini, A.; Cioni, J.-M.; Viero, G.; Codazzi, F.; Consalez, G. G.
10.1101/2023.05.17.540919 — neuroscience — Posted on 2023-05-26
654 Gastrointestinal transit mathematical model in mice treated with antibiotics
Maskawa, R.; Takayasu, L.; Takayasu, H.; Watanabe, K.; Takemine, S.; Kakimoto, T.; Takeshita, K.; Narushima, S.; Suda, W.; Takayasu, M.
10.1101/2023.05.05.539495 — physiology — Posted on 2023-05-26
656 Massive genome reduction occurred prior to the origin of coral algal symbionts
Shah, S.; Dougan, K. E.; Chen, Y.; Lo, R.; Laird, G.; Fortuin, M. D. A.; Rai, S. K.; Murigneux, V.; Bellantuono, A. J.; Rodriguez-Lanetty, M.; Bhattacharya, D.; Chan, C. X.
10.1101/2023.03.24.534093 — genomics — Posted on 2023-05-25
657 Short-range interactions between fibrocytes and CD8+ T cells in COPD bronchial inflammatory response
Eyraud, E.; Maurat, E.; Sac-Epee, J.-M.; Henrot, P.; Zysman, M.; Esteves, P.; Trian, T.; Dupuy, J.-W.; Leipold, A.; Saliba, A.-E.; Begueret, H.; Girodet, P.-O.; Thumerel, M.; Hustache-Castaing, R.; Marthan, R.; Levet, F.; Vallois, P.; Contin-Bordes, C.; Berger, P.; Dupin, I.
10.1101/2022.10.21.513138 — pathology — Posted on 2023-05-26
659 Structural insights into inherited anemia CDA-I: disease-associated mutations disrupt CDIN1-Codanin1 complex
Stojaspal, M.; Brom, T.; Janovic, T.; Necasova, I.; Veverka, P.; Uhrik, L.; Hernychova, L.; Hofr, C.
10.1101/2023.05.25.542057 — biochemistry — Posted on 2023-05-26
665 Archaic introgression contributed to shape the adaptive modulation of angiogenesis and nitric oxide induction in human high-altitude populations from the Himalayas
Ferraretti, G.; Abondio, P.; Alberti, M.; Dezi, A.; Sherpa, P. T.; Cocco, P.; Tiriticco, M.; Di Marcello, M.; Gnecchi-Ruscone, G. A.; Natali, L.; Corcelli, A.; Marinelli, G.; Peluzzi, D.; Sarno, S.; Sazzini, M.
10.1101/2023.05.23.540768 — evolutionary biology — Posted on 2023-05-25
667 Discovery of reactive peptide inhibitors of human papillomavirus oncoprotein E6
Ye, X.; Zhang, P.; Tao, J.; Wang, J. C. K.; Mafi, A.; Grob, N. M.; Quartararo, A. J.; Baddock, H. T.; Foe, I.; Loas, A.; Eaton, D. L.; Hao, Q.; Nile, A. H.; Pentelute, B. L.
10.1101/2023.05.25.542341 — molecular biology — Posted on 2023-05-25
668 Identification of post-transcriptional modifications in nucleic acid sequences using propose-designed molecular beacons
Sahu, P.; Pereira, G.; Wang, J.; Dokholyan, N.; Szeliski, K.; tran, V.; Korneck, M.; Tigges, J.; Jones, J.; Ghiran, I.
10.1101/2023.05.25.542360 — molecular biology — Posted on 2023-05-25
674 Commensal protists in reptiles display flexible host range and adaptation to ectothermic hosts
Gerrick, E. R.; DeSchepper, L. B.; Mechler, C. M.; Joubert, L.-M.; Dunker, F.; Colston, T. J.; Howitt, M. R.
10.1101/2023.05.25.542353 — microbiology — Posted on 2023-05-25
679 Cation permeability and pore dynamics in TRPV1 ion channels
Garcia-Avila, M.; Tello Marmolejo, J.; Rosenbaum, T.; Islas, L. D.
10.1101/2023.05.25.542342 — biophysics — Posted on 2023-05-25
680 Improving few-shot learning-based protein engineering with evolutionary sampling
Jawaid, M. Z.; Yeo, R. W.; Gautam, A.; Gainous, T. B.; Hart, D. O.; Daley, T. P.
10.1101/2023.05.23.541997 — bioinformatics — Posted on 2023-05-25
685 An Alzheimer's disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons
Cukier, H. N.; Duarte, C. L.; Laverde-Paz, M. J.; Simon, S. A.; Van Booven, D. J.; Miyares, A. T.; Whitehead, P. L.; Hamilton-Nelson, K. L.; Adams, L. D.; Carney, R. M.; Cuccaro, M. L.; Vance, J. M.; Pericak-Vance, M. A.; Griswold, A. J.; Dykxhoorn, D. M.
10.1101/2023.05.25.542316 — genetics — Posted on 2023-05-25
686 Massive invasion of organellar DNA drives nuclear genome evolution in Toxoplasma
Namasivayam, S.; Sun, C.; Bah, A. B.; Oberstaller, J.; Pierre-Louis, E.; Etheridge, R. D.; Feschotte, C.; Pritham, E. J.; Kissinger, J. C.
10.1101/2023.05.22.539837 — evolutionary biology — Posted on 2023-05-25
688 Direct androgen receptor regulation of sexually dimorphic gene expression in the mammalian kidney
Xiong, L.; Liu, J.; Han, S. Y.; Koppitch, K.; Guo, J.-J.; Rommelfanger, M.; Gao, F.; Hallgrimsdottir, I. B.; Pachter, L.; Kim, J.; MacLean, A. L.; McMahon, A.
10.1101/2023.05.06.539585 — developmental biology — Posted on 2023-05-25
689 Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids
Huang, B.; Zeng, Z.; Li, H.; Li, Z.; Chen, X.; Guo, J.; Zhang, C. C.; Schreiber, M. E.; Vonk, A.; Xiang, T.; Patel, T.; Li, Y.; Parvez, R.; Der, B.; Chen, J. H.; Liu, Z.; Thornton, M. E.; Grubbs, B. H.; Diao, Y.; Dou, Y.; Gnedeva, K.; Lindstrom, N. O.; Ying, Q.-L.; Pastor-Soler, N. M.; Fei, T.; Hallows, K. R.; McMahon, A. P.; Li, Z.
10.1101/2023.05.25.542343 — developmental biology — Posted on 2023-05-25
692 Internal Ribosome Entry Sites act as Effector Domain in linear and circular antisense long non-coding SINEUP RNAs
Sabrina, D.; Tettey-Matey, A.; Volpe, M.; Pierattini, B.; Ansaloni, F.; Lau, P.; Bon, C.; Peruzzo, O.; Braccia, C.; Armirotti, A.; Scarpato, M.; Damiani, D.; Di Carlo, V.; Broglia, L.; Bechara, E.; Tartaglia, G. G.; Carninci, P.; Santoro, C.; Persichetti, F.; Pandolfini, L.; Espinoza, S.; Zucchelli, S.; Sanges, R.; Gustincich, S.
10.1101/2023.05.25.542260 — molecular biology — Posted on 2023-05-25
693 Three genes controlling streptomycin susceptibility in Agrobacterium fabrum
Howarth, R. E.; Pattillo, C. M.; Griffitts, J. S.; Calvopina-Chavez, D. G.
10.1101/2023.05.25.542317 — microbiology — Posted on 2023-05-25
695 Longitudinal host transcriptional responses to SARS-CoV-2 infection in adults with extremely high viral load
Avadhanula, V.; Creighton, C. J.; Ferlic-Stark, L.; Sucgang, R.; Zhang, Y.; Nagaraj, D.; Nicholson, E. G.; Rajan, A.; Menon, V. K.; Doddapaneni, H.; Muzny, D. M.; Metcalf, G. A.; Cregeen, S. J. J.; Hoffman, K. L.; Gibbs, R. A.; Petrosino, J. J.; Piedra, P. A.
10.1101/2023.05.24.542181 — microbiology — Posted on 2023-05-25
696 Colonization and Dissemination of Klebsiella pneumoniae is Dependent on Dietary Carbohydrates
Hecht, A. L.; Harling, L. C.; Friedman, E. S.; Tanes, C.; Lee, J.; Firrman, J.; Tu, V.; Liu, L.; Bittinger, K.; Goulian, M.; Wu, G. D.
10.1101/2023.05.25.542283 — microbiology — Posted on 2023-05-25
699 Vascular Endothelial-derived SPARCL1 Exacerbates Viral Pneumonia Through Pro-Inflammatory Macrophage Activation
Zhao, G.; Gentile, M. E.; Xue, L.; Cosgriff, C. V.; Weiner, A. I.; Adams-Tzivelekidis, S.; Wong, J.; Li, X.; Kass-Gergi, S.; Holcomb, N. P.; Basil, M. C.; Steward, K. M.; Planer, J. D.; Cantu, E.; Christi, J. D.; Crespo, M. M.; Mitchell, M. J.; Meyer, N. J.; Vaughan, A. E.
10.1101/2023.05.25.541966 — immunology — Posted on 2023-05-25
700 Dichotomy of neutralizing antibody, B cell and T cell responses to SARS-CoV-2 vaccination and protection in healthy adults
Carr, E. J.; Townsley, H.; Wu, M. Y.; Wilkinson, K. A.; Hobson, P. S.; Levi, D.; Namjou, S.; Mears, H. V.; Hobbs, A.; Ragno, M.; Herman, L. S.; Harvey, R.; Bailey, C.; Fowler, A. S.; Hatipoglu, E.; Ngai, Y.; Clayton, B.; Miah, M.; Bawumia, P.; Miranda, M.; Smith, C.; Sawyer, C.; Kelly, G.; Mahalingasivam, V.; Zheng, B.; Evans, S. J.; Libri, V.; Riddell, A.; Nicod, J.; O'Reilly, N.; Howell, M.; Williams, B.; Wilkinson, R. J.; Kassiotis, G.; Swanton, C.; Gandhi, S.; Beale, R. C.; Bauer, D. L.; Wall, E. C.
10.1101/2023.05.24.541920 — immunology — Posted on 2023-05-25
705 Pathogenic Mutations in the C2A Domain of Dysferlin form Amyloid that Activates the Inflammasome.
Scott, I. L.; Dominguez, M. J.; Snow, A.; Harsini, F. M.; Williams, J.; Fuson, K. L.; Thapa, R.; Bhattacharjee, P.; Cornwall, G. A.; Keyel, P. A.; Sutton, R. B.
10.1101/2023.04.24.538129 — biophysics — Posted on 2023-05-25
707 Absolute quantification of photoreceptor outer segment proteins
Skiba, N. P.; Lewis, T. R.; Spencer, W. J.; Castillo, C. M.; Shevchenko, A.; Arshavsky, V. Y.
10.1101/2023.01.19.524794 — biochemistry — Posted on 2023-05-25
708 Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis
Jarysta, A.; Tadenev, A. L. D.; Day, M.; Krawchuk, B.; Low, B. E.; Wiles, M. V.; Tarchini, B.
10.1101/2023.05.25.542257 — developmental biology — Posted on 2023-05-25
712 Differentiation of related events in hippocampus supports memory reinstatement in development
Varga, N. L.; Roome, H. E.; Molitor, R. J.; Martinez, L.; Hipskind, E. M.; Mack, M. L.; Preston, A. R.; Schlichting, M. L.
10.1101/2023.05.25.541743 — neuroscience — Posted on 2023-05-25
713 Micromagnetic Stimulation (μMS) Controls Dopamine Release: An in vivo Study Using WINCS Harmoni
Saha, R.; Goyal, A.; Yuen, J.; Oh, Y.; Bloom, R. P.; Benally, O. J.; Wu, K.; Netoff, T. I.; Low, W. C.; Bennet, K. E.; Lee, K. H.; Wang, J.-P.
10.1101/2023.05.25.542334 — neuroscience — Posted on 2023-05-25
714 Mouse models of SYNGAP1-related intellectual disability
Araki, Y.; Gerber, E. E.; Rajkovich, K. E.; Hong, I.; Johnson, R. C.; Lee, H.-K.; Kirkwood, A.; Huganir, R. L.
10.1101/2023.05.25.542312 — neuroscience — Posted on 2023-05-25
715 Projectome-defined subtypes and modular intra-hypothalamic subnetworks of peptidergic neurons
Jiao, Z.; Gao, T.; Wang, X.; Zhang, W.; Biglari, N.; Boxer, E. E.; Steuernagel, L.; Ding, X.; Yu, Z.; Li, M.; Hao, M.; Zhou, H.; Cao, X.; Li, S.; Jiang, T.; Qi, J.; Jia, X.; Feng, Z.; Ren, B.; Chen, Y.; Shi, X.; Wang, D.; Wang, X.; Han, L.; Liang, Y.; Wang, C.; Li, E.; Hu, Y.; Tao, Z.; Li, H.; Xiang, Y.; Xu, M.; Chang, H.-C.; Zhang, Y.; Xu, H.-t.; Yan, J.; Li, A.; Luo, Q.; Stoop, R.; Sternson, S.; Bruning, J. C.; Poo, M.-m.; Anderson, D. J.; Gong, H.; Sun, Y.; Xu, X.-H.
10.1101/2023.05.25.542241 — neuroscience — Posted on 2023-05-25
717 A mechanistically novel peptide agonist of the IL-7 receptor that addresses limitations of IL-7 cytokine therapy
Dower, W. J.; Park, A. I.; Bakker, A. V.; Cwirla, S. E.; Pongtornpipat, P.; Williams, B. M.; Joshi, P.; Baxter, B. A.; Needels, M. C.; Barrett, R. W.
10.1101/2023.05.24.542196 — immunology — Posted on 2023-05-25
718 The epigenomic landscape of single vascular cells reflects developmental origin and identifies disease risk loci
Weldy, C. S.; Cheng, P. P.; Gu, W.; Pedroza, A. J.; Dalal, A. R.; Worssam, M. D.; Sharma, D.; Nguyen, T.; Kundu, R. K.; Fischbein, M. P.; Quertermous, T.
10.1101/2022.05.18.492517 — genomics — Posted on 2023-05-25
722 Genomic language model predicts protein co-regulation and function
Hwang, Y.; Cornman, A. L.; Kellogg, E.; Ovchinnikov, S.; Girguis, P.
10.1101/2023.04.07.536042 — bioinformatics — Posted on 2023-05-25
723 A comparative genomics approach reveals a local genetic signature of Leishmania tropica in Morocco
Talimi, H.; Daoui, O.; Bussotti, G.; Mhaidi, I.; Boland, A.; Deleuze, J.-F.; Fissoune, R.; Spaeth, G. F.; Lemrani, M.
10.1101/2023.05.25.542267 — genomics — Posted on 2023-05-25
724 Regional Gene Expression in the Retina, Optic Nerve Head, and Optic Nerve of Mice with Experimental Glaucoma and Optic Nerve Crush
Keuthan, C. J.; Schaub, J.; Wei, M.; Fang, W.; Quillen, S.; Kimball, E.; Johnson, T. V.; Ji, H.; Zack, D. J.; Quigley, H. A.
10.1101/2023.02.21.529410 — molecular biology — Posted on 2023-05-25
725 Sociodemographic effects on immune cell composition in a free-ranging non-human primate.
Rosado, M. R. S.; Marzan-Rivera, N.; Watowich, M. M.; Negron-Del Valle, A. D.; Pantoja, P.; Pavez-Fox, M. A.; Siracusa, E. R.; Negron-Del Valle, J. E.; Phillips, D.; Ruiz-Lambides, A.; Cayo Biobank Research Unit, ; Martinez, M. I.; Montague, M. J.; Platt, M. L.; Higham, J. P.; Brent, L. J. N.; Sariol, C. A.; Snyder-Mackler, N.
10.1101/2021.12.06.471383 — immunology — Posted on 2023-05-25
726 The hippocampus of the common marmoset is a GPS, but G is for gaze
Piza, D. B.; Corrigan, B. W.; Gulli, R. A.; Do Carmo, S.; Cuello, A. C.; Muller, L.; Martinez-Trujillo, J. C.
10.1101/2023.05.24.542209 — neuroscience — Posted on 2023-05-25
727 Hippocampal neurons code individual episodic memories in humans
Kolibius, L. D.; Roux, F.; Parish, G. M.; ter Wal, M. J.; Van Der Plas, M.; Chelvarajah, R.; Sawlani, V.; Rollings, D.; Lang, J.; Gollwitzer, S.; Walther, K.; Hopfengaertner, R.; Kreiselmeyer, G.; Hamer, H.; Staresina, B. P.; Wimber, M.; Bowman, H.; Hanslmayr, S.
10.1101/2021.06.28.450149 — neuroscience — Posted on 2023-05-25
728 DISE contributes to neurotoxicity in Alzheimer's disease
Paudel, B.; Jeong, S.-Y.; Martinez, C. P.; Rickman, A.; Haluck-Kangas, A.; Bartom, E. T.; Frederiksen, K.; Affaneh, A.; Kessler, J. A.; Mazzulli, J. R.; Murmann, A. E.; Rogalski, E.; Geula, C.; Ferreira, A.; Heckmann, B. L.; Green, D. R.; Sadleir, K. R.; Vassar, R.; Peter, M. E.
10.1101/2022.09.08.507157 — neuroscience — Posted on 2023-05-25
730 The landscape of biomedical research
Gonzalez-Marquez, R.; Schmidt, L.; Schmidt, B. M.; Berens, P.; Kobak, D.
10.1101/2023.04.10.536208 — scientific communication and education — Posted on 2023-05-25
731 Oxaliplatin-induced cardiotoxicity in mice is connected to the changes in energy metabolism in the heart tissue
Du, J.; Sudlow, L. C.; Shahverdi, K.; Zhou, H.; Michie, M.; Schindler, T. H.; Mitchell, J. D.; Mollah, S.; Berezin, M. Y.
10.1101/2023.05.24.542198 — pharmacology and toxicology — Posted on 2023-05-25
733 Genetic Determinants Underlying the Progressive Phenotype of Beta-lactam/Beta-lactamase Inhibitor Resistance in Escherichia coli
Shropshire, W. C.; Amiji, H.; Bremer, J.; Selvaraj Anand, S.; Strope, B.; Sahasrabhojane, P.; Gohel, M.; Aitken, S.; Spitznogle, S.; Zhan, X.; Kim, J.; Greenberg, D. E.; Shelburne, S. A.
10.1101/2023.05.24.542208 — genomics — Posted on 2023-05-25
737 Comprehensive map of ribosomal 2'-O-methylation and C/D box snoRNAs in Drosophila melanogaster
Sklias, A.; Cruciani, S.; Marchand, V.; Spagnuolo, M.; Lavergne, G.; Bourguignon, V.; Dreos, R.; Novoa, E. M.; Motorin, Y.; Roignant, J.-Y.
10.1101/2023.05.25.542231 — molecular biology — Posted on 2023-05-25
739 Vaccination with Helicobacter pylori attachment proteins protects against gastric cancer
Boren, T.; Bugaytsova, J. A.; Piddubnyi, A.; Tkachenko, I.; Rakhimova, L.; Olofsson Edlund, J.; Thorell, K.; Marcotte, H.; Lundquist, A.; Schon, K.; Suerbaum, S.; Schulz, C.; Malfertheiner, P.; Hansen, L. M.; Solnick, J. V.; Moskalenko, R.; Hammarstrom, L.
10.1101/2023.05.25.542131 — immunology — Posted on 2023-05-25
742 Rapid intracellular acidification is a novel plant defense response countered by the brown planthopper
Jiang, Y.; Zhang, X.-Y.; Li, S.; Xie, Y.-C.; Li, Z.; Jin, D.; Yang, Y.; Pu, Z.; Zhang, L.; Lu, J.-B.; Huang, H.-J.; Zhang, C.-X.; He, S. Y.
10.1101/2023.05.24.542203 — plant biology — Posted on 2023-05-25
743 Hijacking of internal calcium dynamics by intracellularly residing rhodopsins
Eria-Oliveira, A.-S.; Folacci, M.; Chassot, A. A.; Fedou, S.; Theze, N.; Zabelskii, D.; Alekseev, A.; Bamberg, E.; Gordeliy, V.; Sandoz, G.; Vivaudou, M.
10.1101/2023.05.25.542240 — physiology — Posted on 2023-05-25
744 Tyramine promotes colon cancer risk and development by inducing DNA damage and inflammation
Glymenaki, M.; Curio, S.; Shrestha, S.; El-Bahrawy, M. A.; Wang, Y.; Gooderham, N.; Guerra, N.; Li, J. V.
10.1101/2023.05.25.542254 — cancer biology — Posted on 2023-05-25
745 The mechanical response of vinculin
Liu, X.; Wang, Y.; Yao, M.; Baker, K. B.; Klapholz, B.; Brown, N. H. T.; Goult, B. T.; Yan, J.
10.1101/2023.05.25.542235 — biophysics — Posted on 2023-05-25
748 Comparing sparse inertial sensor setups for sagittal-plane walking and running reconstructions
Dorschky, E.; Nitschke, M.; Mayer, M.; Weygers, I.; Gassner, H.; Seel, T.; Eskofier, B.; Koelewijn, A.
10.1101/2023.05.25.542228 — bioengineering — Posted on 2023-05-25
749 Contrasting functions of ATP hydrolysis by MDA5 and LGP2 in viral RNA sensing
Singh, R.; Wu, Y.; Herrero del Valle, A.; Leigh, K. E.; Cheng, M. T. K.; Ferguson, B. J.; Modis, Y.
10.1101/2023.05.25.542247 — biochemistry — Posted on 2023-05-25
750 Beclin1-Deficient Adipocytes Promote Tumor Progression by YAP/TAZ-dependent Adipocyte Transformation
Song, Y.; Na, H.; Lee, S. E.; Nam, T.; Kim, Y. M.; Ji, Y.; Jin, Y.; Park, J.-H.; Cho, S. C.; Hwang, D.; Ha, S.-J.; Park, H. W.; Kim, J. B.; Lee, H. W.; Moon, J.
10.1101/2023.05.25.542253 — biochemistry — Posted on 2023-05-25
753 Applying genomic approaches to identify historic population declines in European forest bats
Razgour, O.; Montauban, C.; Festa, F.; Whitby, D.; Juste, J.; Ibanez, C.; Rebelo, H.; Afonso, S.; Bekaert, M.; Jones, G.; Williams, C.; Boughey, K.
10.1101/2023.05.24.542071 — genomics — Posted on 2023-05-25
756 Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal development
Yue, T.; Guo, Y.; Qi, X.; Zheng, W.; Zhang, H.; Wang, B.; Zhou, B.; Zeng, X.; Ouzhuluobu, ; He, Y.; Su, B.
10.1101/2023.05.24.542081 — evolutionary biology — Posted on 2023-05-25
758 Extensive DNA methylome rearrangement during early lamprey embryogenesis
Angeloni, A.; Fissette, S.; Kaya, D.; Hammond, J. M.; Gamaarachchi, H.; Deveson, I. W.; Klose, R. J.; Li, W.; Zhang, X.; Bogdanovic, O.
10.1101/2023.05.25.542242 — developmental biology — Posted on 2023-05-25
760 NSC95397 is a Novel HIV Latency Reversing Agent
Nichols Doyle, R.; Yang, V.; Damoiseaux, R.; Fregoso, O. I.
10.1101/2023.05.24.542213 — microbiology — Posted on 2023-05-25
761 Microbiota produced indole metabolites disrupt host cell mitochondrial energy production and inhibit Cryptosporidium parvum growth
Funkhouser-Jones, L.; Xu, R.; Wilke, G.; Fu, Y.; Shriefer, L. A.; Makimaa, H.; Rodgers, R.; Kennedy, E. A.; VanDussen, K.; Stappenbeck, T.; Baldridge, M. T.; Sibley, L. D.
10.1101/2023.05.25.542157 — microbiology — Posted on 2023-05-25
763 Changes in the gut mycobiome are associated with Type 2 diabetes mellitus and metformin treatment across populations
Van Syoc, E.; Nixon, M. P.; Silverman, J. D.; Luo, Y.; Gonzalez, F. J.; Elbere, I.; Klovins, J.; Patterson, A. D.; Rogers, C. J.; Ganda, E.
10.1101/2023.05.25.542255 — microbiology — Posted on 2023-05-25
764 The tumor microbiome as a predictor of outcomes in patients with metastatic melanoma treated with immune checkpoint inhibitors
Wheeler, C. E.; Coleman,, S. S.; Hoyd, R.; Denko, L.; Chan, C. H. F.; Churchman, M. L.; Denko, N.; Dodd, R. D.; Eljilany, I.; Hardikar, S.; Husain, M.; Ikeguchi, A. P.; Jin, N.; Ma, Q.; McCarter, M. D.; Osman, A. E. G.; Robinson, L. A.; Singer, E. A.; Tinoco, G.; Ulrich, C. M.; Zakharia, Y.; Spakowicz, D.; Tarhini, A. A.; Tan, A. C.
10.1101/2023.05.24.542123 — immunology — Posted on 2023-05-25
765 Tempered IL-2 Signals Program PD-1 Checkpoint Blockade-Responsive Stem-like Exhausted T Cells During Priming
Kalia, V.; Reed, J.; Khanna, A.; Toumi, R.; Xiao, H.; Pulliam, T.; Deo, R.; Nghiem, P.; Sarkar, S.
10.1101/2023.05.25.541936 — immunology — Posted on 2023-05-25
766 The hippocampus of the common marmoset is a GPS, but G is for gaze
Piza, D. B.; Corrigan, B. W.; Gulli, R. A.; Do Carmo, S.; Cuello, A. C.; Muller, L.; Martinez-Trujillo, J. C.
10.1101/2023.05.24.542209 — neuroscience — Posted on 2023-05-25
770 Prenatal experience with language shapes the brain
Mariani, B.; Nicoletti, G.; Barzon, G.; Barajas, M. C. O.; Shukla, M.; Guevara, R.; Suweis, S.; Gervain, J.
10.1101/2023.05.25.542259 — neuroscience — Posted on 2023-05-25
771 Local contribution to the somatosensory evoked potentials in rat's thalamus
Sredniawa, W.; Borzymowska, Z.; Kondrakiewicz, K.; Jurgielewicz, P.; Mindur, B.; Wojcik, D. K.; Kublik, E.
10.1101/2023.05.25.541803 — neuroscience — Posted on 2023-05-25
773 Imaging Mass Cytometry-Driven Spatial Analysis and Biomarker Discovery in Hodgkin Lymphoma
Xu, A. M.; Jiang, A. M.; Aoki, T.; Gamboa, A.; Chong, L.; Colombo, A. R.; Yin, Y.; Lownik, J.; Takata, K.; Hav, M.; Steidl, C.; Merchant, A.
10.1101/2023.05.24.542195 — cancer biology — Posted on 2023-05-25
774 Various Cell Types in the Bone Marrow sustain Primary B-Cell Precursor Acute Lymphoblastic Leukemia
Smeets, M. W. E.; van de Ven, C.; Orsel, J.; Reichert, C. E. J.; Boeree, A.; Boer, J. M.; den Boer, M. L.
10.1101/2023.05.25.542080 — cancer biology — Posted on 2023-05-25
775 Spatial relationships in the urothelial and head and neck tumor microenvironment predict response to combination immune checkpoint inhibitors
Gil-Jimenez, A.; van Dijk, N.; Vos, J. L.; Lubeck, Y.; van Montfoort, M. L.; Peters, D.; Hooijberg, E.; Broeks, A.; Zuur, C. L.; van Rhijn, B.; Vis, D. J.; van der Heijden, M. S.; Wessels, L. F. A.
10.1101/2023.05.25.542236 — cancer biology — Posted on 2023-05-25
776 Designing patient-oriented combination therapies for acute myeloid leukemia based on efficacy/toxicity integration and bipartite network modeling
Mirzaie, M.; Gholizadeh, E.; Miettinen, J. J.; Ruokoranta, T.; Ianevsk, P.; Saarela, J.; Manninen, M.; Miettinen, S.; Heckman, C. A.; Jafari, M.
10.1101/2023.05.25.542238 — cancer biology — Posted on 2023-05-25
777 Water will find a way: transport through narrow tunnels in hydrolases
Sequeiros-Borja, C.; Thirunavukarasu, A. S.; Dongmo Foumthuim, C. J.; Brezovsky, J.
10.1101/2023.05.24.542065 — bioinformatics — Posted on 2023-05-25
779 FuzzyPPI: Human Proteome at Fuzzy Semantic Space
Halder, A. K.; Bandyopadhyay, S. S.; Jedrzejewsk, W.; Basu, S.; Sroka, J.
10.1101/2023.05.24.541959 — bioinformatics — Posted on 2023-05-25
781 An all-atom protein generative model
Chu, A. E.; Cheng, L.; El Nesr, G.; Xu, M.; Huang, P.-S.
10.1101/2023.05.24.542194 — bioengineering — Posted on 2023-05-25
782 Efficient and accurate prediction of protein structure using RoseTTAFold2
Baek, M.; Anishchenko, I.; Humphreys, I.; Cong, Q.; Baker, D.; DiMaio, F.
10.1101/2023.05.24.542179 — biochemistry — Posted on 2023-05-25
785 Cell type deconvolution of bulk blood RNA-Seq to reveal biological insights of neuropsychiatric disorders
Boltz, T.; Schwarz, T.; Bot, M.; Hou, K.; Caggiano, C.; Lapinska, S.; Duan, C.; Boks, M. P.; Kahn, R. S.; Zaitlen, N.; Pasaniuc, B.; Ophoff, R. A.
10.1101/2023.05.24.542156 — genomics — Posted on 2023-05-25
792 Learning virus genotype-fitness landscape in embedding space
Liu, Y.; Luo, Y.; Lu, X.; Gao, H.; He, R.; Zhang, X.; Zhang, X.; Li, Y.
10.1101/2023.02.09.527693 — evolutionary biology — Posted on 2023-05-25
793 A combination of convergent extension and differential adhesion explains the shapes of elongating gastruloids
de Jong, M. A.; Adegeest, E.; Berenger-Currias, N. M. L. P.; Mircea, M.; Merks, R. M. H.; Semrau, S.
10.1101/2023.05.24.541949 — developmental biology — Posted on 2023-05-25
794 A single cell transcriptomic fingerprint of stressed premature, imbalanced differentiation of embryonic stem cells.
Ruden, X.; Singh, A.; Marben, T.; Tang, W.; Awonuga, A.; Ruden, D. M.; Puscheck, E.; Feng, H.; Rappolee, D.
10.1101/2023.05.23.541952 — developmental biology — Posted on 2023-05-25
796 The phosphoinositide signature guides the final step of plant cytokinesis
Lebecq, A.; Golgy, C.; Fangain, A.; Gascon, E.; Belcram, K.; Pastuglia, M.; Bouchez, D.; Caillaud, M.-C.
10.1101/2022.12.18.520917 — cell biology — Posted on 2023-05-25
797 Phase separation of Treacle is indispensable for ribosomal transcription and DNA repair.
Velichko, A. K.; Kovina, A. P.; Luzhin, A. V.; Petrova, N. V.; Deriglazov, D. A.; Kazakov, E. P.; Kireev, I. I.; Shender, V. O.; Arapidi, G. P.; Razin, S. V.; Kantidze, O. L.
10.1101/2023.05.11.540311 — cell biology — Posted on 2023-05-25
798 Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic metabolism to fuel growth.
Kesvari, S.; Masson, J.; Ferrari-Cestari, M.; Bodea, L.-G.; Nooru-Mohamed, F.; Tse, B.; Sokolowski, K.; Batoon, L.; Patkar, O.; Sullivan, M.; Ebersbach, H.; Stutz, C.; Parton, R.; Pettit, A.; Hume, D.; Irvine, K. M.
10.1101/2023.05.17.538022 — immunology — Posted on 2023-05-25
800 Regulation of hippocampal mossy fiber-CA3 synapse function by a Bcl11b/C1ql2/Nrxn3(25b+) pathway
Britsch, S.; Koumoundourou, A.; Rannap, M.; De Bruyckere, E.; Nestel, S.; Reissner, C.; Egorov, A.; Liu, P.; Missler, M.; Heimrich, B.; Draguhn, A.
10.1101/2023.05.23.541921 — neuroscience — Posted on 2023-05-25
803 GASOLINE: detecting germline and somatic structural variants from long-reads data.
Magi, A.; Mattei, G.; Mingrino, A.; Caprioli, C.; Ronchini, C.; Frige, G.; Semeraro, R.; Bolognini, D.; Colombo, E.; Mazzarella, L.; Pelicci, P. G.
10.1101/2023.05.22.541558 — bioinformatics — Posted on 2023-05-25
804 Disease associated human TCR characterization by deep-learning framework TCR-DeepInsight
Xue, Z.; Wu, L.; Tian, R.; Liu, Z.; Bai, Y.; Sun, D.; Guo, Y.; Chen, P.; Zhao, Y.; He, B.; Wang, L.; Yao, J.; Lu, L.; Liu, W.
10.1101/2023.05.22.541406 — bioinformatics — Posted on 2023-05-25
808 Synaptic alterations associated with disrupted sensory encoding in a mouse model of tauopathy
Meftah, S.; Cavallini, A.; Murray, T. K.; Jankowski, L.; Bose, S.; Ashby, M. C.; Brown, J. T.; Witton, J.
10.1101/2023.05.24.542163 — neuroscience — Posted on 2023-05-25
809 Oxaliplatin-induced cardiotoxicity in mice is connected to the changes in energy metabolism in the heart tissue
Du, J.; Sudlow, L. C.; Shahverdi, K.; Zhou, H.; Michie, M.; Schindler, T. H.; Mitchell, J. D.; Berezin, M. Y.
10.1101/2023.05.24.542198 — pharmacology and toxicology — Posted on 2023-05-25
810 RAPSYN-Mediated Neddylation of BCR-ABL Alternatively Determines the Fate of Philadelphia Chromosome-positive Leukemia
Zhao, m.; Dai, B.; Li, X.; Zhang, Y.; Qiao, C.; Qin, Y.; Li, Z.; Li, Q.; Wang, S.; Yang, Y.; Chen, Y.
10.1101/2023.05.24.542110 — cancer biology — Posted on 2023-05-25
811 Noncanonical TRAIL Signaling Facilitates Tumor Immunosuppression and Cholangiocarcinoma Growth via Myeloid-Derived Suppressor Cells
Loeuillard, E.; Li, B.; Stumpf, H. E.; Yang, J.; Tomlinson, J. L.; Graham, R. P.; Smoot, R. L.; Dong, H.; Ilyas, S. I.
10.1101/2023.05.24.541931 — cancer biology — Posted on 2023-05-25
813 Alterations in the preneoplastic breast microenvironment of BRCA1/2 mutation carriers revealed by spatial transcriptomics
Caputo, A.; Vipparthi, K.; Bazeley, P.; Downs-Kelly, E.; McIntire, P.; Ni, Y.; Hu, B.; Keri, R. A.; Karaayvaz, M.
10.1101/2023.05.24.542078 — cancer biology — Posted on 2023-05-25
815 Liquid plug propagation in computer-controlled microfluidic airway-on-a-chip with semi-circular microchannels
Viola, H.; Vasani, V.; Washington, K.; Lee, J. H.; Selva, C.; Li, A.; Llorente, C. J.; Murayama, Y.; Grotberg, J. B.; Romano, F.; Takayama, S.
10.1101/2023.05.24.542177 — bioengineering — Posted on 2023-05-25
816 Growth factor-free, peptide-functionalized gelatin hydrogel promotes arteriogenesis and attenuates tissue damage in a murine model of critical limb ischemia
Curry, C. W.; Sturgeon, S. M.; O'Grady, B. J.; Yates, A. K.; Kjar, A.; Paige, H. A.; Mowery, L. S.; Katdare, K. A.; Patel, R. V.; Mlouk, K.; Stiefbold, M. R.; Vafaie-Partin, S.; Kawabata, A.; McKee, R. M.; Moore-Lotridge, S.; Hawkes, A.; Kusunose, J.; Gibson-Corley, K. N.; Schmeckpeper, J.; Schoenecker, J. G.; Caskey, C. F.; Lippmann, E. S.
10.1101/2023.05.24.542150 — bioengineering — Posted on 2023-05-25
817 Validation of hypermethylated DNA regions found in colorectal cancers as potential aging-independent biomarkers of precancerous colorectal lesions
Sajibu, S.; Sonder, E.; Tiwari, A.; Orjuela, S.; Parker, H. R. D.; The Frans, O.; Gubler, C.; Marra, G.; Robinson, M. D.
10.1101/2023.05.24.542159 — genomics — Posted on 2023-05-25
819 Genetic Determinants Underlying the Progressive Phenotype of Beta-lactam/Beta-lactamase Inhibitor Resistance in Escherichia coli
Shropshire, W. C.; Amiji, H.; Bremer, J.; Selvaraj Anand, S.; Strope, B.; Sahasrabhojane, P.; Gohel, M.; Aitken, S.; Spitznogle, S.; Zhan, X.; Kim, J.; Greenberg, D. E.; Shelburne, S. A.
10.1101/2023.05.24.542208 — genomics — Posted on 2023-05-25
821 In vivo functional phenotypes from a computational epistatic model of evolution
Alvarez, S.; Nartey, C. M.; Mercado, N.; de la Paz, A.; Huseinbegovic, T.; Morcos, F.
10.1101/2023.05.24.542176 — evolutionary biology — Posted on 2023-05-25
822 REGENERATIVE GENE THERAPY IN THE HYPOTHALAMUS PROLONGS FERTILITY IN FEMALE RATS
Gallardo, M. D.; Girard, M.; Bigres, A.; Lehmann, M.; Rodriguez, S. S.; Goya, R.
10.1101/2023.05.24.542027 — neuroscience — Posted on 2023-05-25
823 Endogenous recapitulation of Alzheimers disease neuropathology through human 3D direct neuronal reprogramming
Sun, Z.; Kwon, J.-S.; Ren, Y.; Chen, S.; Cates, K.; Lu, X.; Walker, C. K.; Karahan, H.; Sviben, S.; Fitzpatrick, J. A.; Valdez, C.; Houlden, H.; Karch, C. M.; Bateman, R. J.; Sato, C.; Mennerick, S. J.; Diamond, M. I.; Kim, J.; Tanzi, R. E.; Holtzman, D. M.; Yoo, A. S.
10.1101/2023.05.24.542155 — neuroscience — Posted on 2023-05-25
826 Sessile alveolar macrophage connexin-43 determines mechano-immunity in the lung
Mthunzi, L.; Gusarova, G. A.; Islam, M. N.; Bhattacharya, S.; Bhattacharya, J.
10.1101/2023.05.24.541735 — physiology — Posted on 2023-05-25
828 Compression strategies for large-scale electrophysiology data
Buccino, A. P.; Winter, O.; Bryant, D.; Feng, D.; Svoboda, K.; Siegle, J. H.
10.1101/2023.05.22.541700 — neuroscience — Posted on 2023-05-25
831 Transcriptional reprogramming by IL-2 variant generates metabolically active stem-like T cells
Ortiz Miranda, Y.; Masid, M.; Jimenez-Luna, C.; Montalvo Bereau, G. M.; Muller, T.; Rayroux, N.; Cribioli, E.; Corria-Osorio, J.; Carrasco Hope, H.; Vuillefroy de Silly, R.; Seijo, B.; Ginefra, P.; Leon, K.; Vannini, N.; Ho, P.-C.; Crespo, I.; Hatzimanikatis, V.; Irving, M.; Coukos, G.
10.1101/2023.05.24.541283 — systems biology — Posted on 2023-05-24
832 Genetic basis of lineage-specific evolution of fruit traits in hexaploid persimmon
Horiuchi, A.; Masuda, K.; Shirasawa, K.; Onoue, N.; Matsuzaki, R.; Tao, R.; KUBO, Y.; Ushijima, K.; Akagi, T.
10.1101/2023.05.23.542005 — plant biology — Posted on 2023-05-24
834 Revealing the Oligomerization of Channelrhodopsin-2 in the Cell Membrane using Photo-Activated Localization Microscopy
Bestsennaia, E.; Maslov, I.; Balandin, T.; Alekseev, A.; Yudenko, A.; Shamseye, A. A.; Zabelskii, D.; Baumann, A.; Catapano, C.; Karathanasis, C.; Gordeliy, V.; Heilemann, M.; Gensch, T.; Borshchevskiy, V.
10.1101/2023.05.24.542088 — biophysics — Posted on 2023-05-24
838 Phylogenetic and spatial determinants of leaf endophyte microbiomes in the flowering plant genus Heuchera (Saxifragaceae)
Pantinople, D. J.; Conner, R.; Sutton-Dauber, S.; Broussard, K.; Siniscalchi, C. M.; Engle-Wrye, N. J.; Jordan, H. R.; Folk, R. A.
10.1101/2023.05.23.541975 — ecology — Posted on 2023-05-24
839 Mutation Patterns Predict Drug Sensitivity in Acute Myeloid Leukemia
Qin, G.; Dai, J.; Chien, S.; Martins, T. J.; Loera, B.; Nguyen, Q.; Oakes, M. L.; Tercan, B.; Aguilar, B.; Hagen, L.; McCune, J.; Gelinas, R.; Monnat, R. J.; Shmulevich, I.; Becker, P. S.
10.1101/2023.05.24.541944 — cell biology — Posted on 2023-05-24
840 Hierarchical Modelling of Crossing Fibres in the White Matter
Rafipoor, H.; Lange, F. J.; Arthofer, C.; Cottaar, M.; Jbabdi, S.
10.1101/2023.05.24.542138 — neuroscience — Posted on 2023-05-25
841 HNF4α mediated QPRT expression in the kidney facilitates resilience against acute kidney injury
Clark, A. J.; Saade, M. C.; Vemireddy, V.; Vu, K. Q.; Flores, B. M.; Etzrodt, V.; Ciampa, E. J.; Huang, H. J.; Takakura, A.; Zandi-Nejad, K.; Zsengeller, Z. K.; Parikh, S. M.
10.1101/2023.05.23.541987 — physiology — Posted on 2023-05-24
842 The Duality of Adiponectin and the Role of Sex in Atherosclerosis
Cullen, A. E.; Centner, A. M.; Deitado, R.; Ukhanov, V.; Ismaeel, A.; Koutakis, P.; Muller-Delp, J.; Salazar, G.
10.1101/2023.05.23.541764 — physiology — Posted on 2023-05-24
843 Serine synthesis pathway upregulated by E-cadherin is essential for the proliferation and metastasis of breast cancers
Lee, G.; Wong, C.; Cho, A.; West, J. J.; Crawford, A. J.; Russo, G. C.; Si, B. R.; Kim, J.; Hoffner, L.; Jang, C.; Jung, M.; Leone, R. D.; Konstantopoulos, K.; Ewald, A. J.; Wirtz, D.; Jeong, S.
10.1101/2023.05.24.541452 — cancer biology — Posted on 2023-05-24
844 Tumor-resident regulatory T cells in pancreatic cancer express the αvβ5 integrin as a targetable activation marker
Suzuki, K.; Kunisada, Y.; Miyamura, N.; Eikawa, S.; Hurtado de Mendoza, T.; Mose, E. S.; Lu, C.; Kuroda, Y.; Ruoslahti, E.; Lowy, A. M.; Sugahara, K. N.
10.1101/2023.05.24.542137 — cancer biology — Posted on 2023-05-24
846 RNA structures and dynamics with A resolution revealed by x-ray free electron lasers
Zielinski, K. A.; Sui, S.; Pabit, S. A.; Rivera, D. A.; Wang, T.; Hu, Q.; Kashipathy, M. M.; Lisova, S.; Schaffer, C. B.; Mariani, V.; Hunter, M. S.; Kupitz, C. J.; Moss, F. R.; Poitevin, F. P.; Grant, T. D.; Pollack, L.
10.1101/2023.05.24.541763 — biophysics — Posted on 2023-05-24
848 A bioinformatics tool for identifying intratumoral microbes from the ORIEN dataset
Wang, C.; Ma, A.; McNutt, M. E.; Hoyd, R.; Wheeler, C. E.; Robinson, L. A.; Chan, C. H. F.; Zakharia, Y.; Dodd, R. D.; Ulrich, C. M.; Hardikar, S.; Churchman, M. L.; Tarhini, A. A.; Singer, E. A.; Ikeguchi, A. P.; McCarter, M. D.; Denko, N.; Tinoco, G.; Husain, M.; Jin, N.; Osman, A. E. G.; Eljilany, I.; Tan, A. C.; Coleman,, S. S.; Denko, L.; Riedlinger, G.; Schneider, B. P.; Spakowicz, D.; Ma, Q.
10.1101/2023.05.24.541982 — bioinformatics — Posted on 2023-05-24
850 Improving few-shot learning-based protein engineering with evolutionary sampling
Jawaid, M. Z.; Yeo, R. W.; Gautam, A.; Gainous, T. B.; Hart, D. O.; Daley, T. P.
10.1101/2023.05.23.541997 — bioinformatics — Posted on 2023-05-24
853 Urbanisation generates multiple trait syndromes for terrestrial taxa worldwide
Hahs, A. K.; Fournier, B.; Aronson, M. F. J.; Nilon, C. H.; Herrera-Montes, A.; Salisbury, A.; Threlfall, C. G.; Rega-Brodsky, C. C.; Lepczyk, C. A.; La Sorte, F. A.; MacGregor-Fors, I.; MacIvor, J. S.; Jung, K.; Piana, M. R.; Williams, N. S. G.; Knapp, S.; Acevedo, A. A.; Gainsbury, A. M.; Rainho, A.; Hamer, A. J.; Shwartz, A.; Voigt, C. C.; Lewanzik, D.; Lowenstein, D. M.; O'Brien, D.; Tommasi, D.; Pineda, E.; Sita Carpenter, E.; Belskaya, E.; Lovei, G.; Makinson, J. C.; Castaneda-Oviedo, J.; Coleman, J.; Sadler, J. P.; Shroyer, J.; Shapiro, J. T.; Baldock, K. C. R.; Ksiazek-Mikenas, K.; Mat
10.1101/2023.05.24.541105 — ecology — Posted on 2023-05-24
854 Differential early-life survival underlies the adaptive significance of temperature-dependent sex determination in a long-lived reptile
Bock, S.; Loera, Y.; Johnson, J.; Smaga, C.; Haskins, D. L.; Tuberville, T.; Singh, R.; Rainwater, T.; Wilkinson, P.; Parrott, B. B.
10.1101/2023.05.24.542140 — ecology — Posted on 2023-05-24
855 A combination of convergent extension and differential adhesion explains the shapes of elongating gastruloids
de Jong, M. A.; Adegeest, E.; Berenger-Currias, N. M. L. P.; Mircea, M.; Merks, R. M. H.; Semrau, S.
10.1101/2023.05.24.541949 — developmental biology — Posted on 2023-05-24
856 The Notch-Pdgfr beta axis suppresses brown adipocyte progenitor differentiation in early postnatal mice
Shi, Z.; Xiong, S.; Hu, R.; Wang, Z.; Park, J.; Qian, Y.; Wang, J.; Bhalla, P.; Velupally, N.; Song, Q.; Song, Z.; Layden, B. T.; Jiang, Y.
10.1101/2023.05.24.541839 — developmental biology — Posted on 2023-05-24
857 Mass-immigration shapes the antibiotic resistome of wastewater treatment plants
Zhang, L.; Adyari, B.; Hou, L.; Yang, X.; Gad, M.; Wang, Y.; Ma, C.; Sun, Q.; Tang, Q.; Zhang, Y.; Yu, C.-P.; Hu, A.
10.1101/2023.02.27.530348 — microbiology — Posted on 2023-05-24
858 Antigen spacing on protein nanoparticles influences antibody responses to vaccination
Ellis, D.; Dosey, A.; Boyoglu-Barnum, S.; Park, Y.-J.; Gillespie, R.; Syeda, H.; Tsybovsky, Y.; Murphy, M.; Pettie, D.; Matheson, N.; Chan, S.; Ueda, G.; Fallas, J.; Carter, L.; Graham, B.; Veesler, D.; Kanekiyo, M.; King, N. P.
10.1101/2023.05.23.541980 — immunology — Posted on 2023-05-24
859 Triphasic production of IFNγ by innate and adaptive lymphocytes following influenza A virus infection
Finney, G. E.; Hargrave, K. E.; Pingen, M.; Purnell, T.; Todd, D.; MacDonald, F.; Worrell, J. C.; MacLeod, M. K.
10.1101/2023.05.23.541923 — immunology — Posted on 2023-05-24
860 Combinatorial immune refocusing within the influenza hemagglutinin head elicits cross-neutralizing antibody responses
Dosey, A.; Ellis, D.; Boyoglu-Barnum, S.; Syeda, H.; Saunders, M.; Watson, M.; Kraft, J. C.; Pham, M. N.; Guttman, M.; Lee, K. K.; Kanekiyo, M.; King, N. P.
10.1101/2023.05.23.541996 — immunology — Posted on 2023-05-24
863 The Striatal Heterodimers A2AR-D2Rs Are Linked To Ergogenic Effects Of Caffeine
Alves, A. C. d. B.; Aguiar, A. S.; Santos, N. d. S.; Tavares, A. P.; Panatta, G.
10.1101/2023.05.24.541930 — neuroscience — Posted on 2023-05-24
864 Mapping the Organization and Morphology of Calcitonin Gene-Related Peptide (CGRP)-IR Axons in the Whole Mouse Stomach
Ma, J.; Nguyen, D.; Madas, J.; Bizanti, A.; Mistareehi, A.; Kwiat, A. M.; Chen, J.; Lin, M.; Christie, R.; Hunter, P.; Heal, M.; Baldwin, S.; Tappan, S.; Furness, J. B.; Powley, T. L.; Cheng, Z. J.
10.1101/2023.05.23.541811 — neuroscience — Posted on 2023-05-24
865 Emotional association enhances perceptual memory through amygdalo-cortical inputs during NREM sleep
Saito, Y.; Osako, Y.; Odagawa, M.; Oisi, Y.; Matsubara, C.; Kato, S.; Kobayashi, K.; Morita, M.; Johansen, J. P.; Murayama, M.
10.1101/2023.05.23.541852 — neuroscience — Posted on 2023-05-24
866 Endogenous pathology in tauopathy mice progresses via brain networks
Ramirez, D. M.; Whitesell, J. D.; Bhagwat, N.; Thomas, T. L.; Ajay, A. D.; Nawaby, A.; Delatour, B.; Bay, S.; Lafaye, P.; Knox, J. E.; Harris, J. A.; Meeks, J. P.; Diamond, M. I.
10.1101/2023.05.23.541792 — neuroscience — Posted on 2023-05-24
868 Quantitative Geometric Modeling of Blood Cells from X-ray Histotomograms of Whole Zebrafish Larvae
Yakovlev, M. A.; Liang, K.; Zaino, C. R.; Vanselow, D. J.; Sugarman, A. L.; Lin, A. Y.; La Riviere, P. J.; Zheng, Y.; Silverman, J. D.; Liechty, J. C.; Huang, S. X.; Cheng, K. C.
10.1101/2023.05.23.541939 — systems biology — Posted on 2023-05-24
871 Overexpression of an apple broad range agglutinating lectin does not promote in planta resistance to fire blight and bacterial wilt.
Bodelot, A.; Chavonet, E.; Brisset, M.-N.; Dousset, N.; Ravon, E.; Heintz, C.; Berthome, R.; Zaffuto, M.; Kempf, M.; Foulon, M.; Marion, E.; Vergne, E.; Degrave, A.
10.1101/2023.05.23.541687 — plant biology — Posted on 2023-05-24
873 The digestive system of a cricket pulverizes polyethylene microplastics
Ritchie, M. W.; Provencher, J.; Allison, J. E.; Muzzatti, M. J.; MacMillan, H. A.
10.1101/2023.05.23.541961 — physiology — Posted on 2023-05-24
874 Pharmaceutical agent cetylpyridinium chloride inhibits immune mast cell function by interfering with calcium mobilization
Obeng, B.; Potts, C. M.; West, B. E.; Burnell, J. E.; Fleming, P. J.; Shim, J. K.; Kinney, M. S.; Ledue, E. L.; Sangroula, S.; Vazquez, A. Y. B.; Gosse, J. A.
10.1101/2023.05.23.541979 — pharmacology and toxicology — Posted on 2023-05-24
877 Acoustically-Targeted Measurement of Transgene Expression in the Brain
Seo, J. P.; Trippett, J. S.; Huang, Z.; Wang, R.; Lee, S.; Szablowski, J. O.
10.1101/2023.05.23.541868 — bioengineering — Posted on 2023-05-24
878 Sex Differences in Human Music Perception are Negligible
Bertolo, M.; Müllensiefen, D.; Peretz, I.; Woolley, S. C.; Sakata, J.; Mehr, S.
10.1101/2023.05.23.541970 — animal behavior and cognition — Posted on 2023-05-24
880 G6PC2 controls glucagon secretion by defining the setpoint for glucose in pancreatic α-cells
Bahl, V.; Waite, E.; Rifkind, R.; Hamdan, Z.; May, C. L.; Manduchi, E.; Voight, B. F.; Lee, M. Y. Y.; Tigue, M.; Manuto, N.; Glaser, B.; Avrahami, D.; Kaestner, K. H.
10.1101/2023.05.23.541901 — genetics — Posted on 2023-05-24
882 Pupil size predicts the onset of exploration in brain and behavior.
Shourkeshti, A.; Marrocco, G.; Jurewicz, K.; Moore, T.; Ebitz, R. B.
10.1101/2023.05.24.541981 — neuroscience — Posted on 2023-05-24
883 Atypical connectome topography and signal flow in temporal lobe epilepsy
Xie, K.; Royer, J.; Lariviere, S.; Rodriguez-Cruces, R.; Frassle, S.; Cabalo, D. G.; Ngo, A.; DeKraker, J.; Auer, H.; Tavakol, S.; Weng, Y.; Abdallah, C.; Horwood, L.; Frauscher, B.; Caciagli, L.; Bernasconi, A.; Bernasconi, N.; Zhang, Z.; Concha, L.; Bernhardt, B.
10.1101/2023.05.23.541934 — neuroscience — Posted on 2023-05-24
885 Differential Contribution of Sensorimotor Cortex and Subthalamic Nucleus to Unimanual and Bimanual Hand Movements
Merrick, C. M.; Doyle, O. N.; Gallegos, N. E.; Irwin, Z. T.; Olson, J. W.; Gonzalez, C. L.; Knight, R. T.; Ivry, R. B.; Walker, H. C.
10.1101/2023.05.23.542003 — neuroscience — Posted on 2023-05-24
888 Global Protein-Turnover Quantification in Escherichia coli Reveals Cytoplasmic Recycling under Nitrogen-Limitation
Gupta, M.; Johnson, A.; Cruz, E.; Costa, E.; Guest, R. L.; Li, S. H.-J.; Hart, E. M.; Nguyen, T.; Stadlmeier, M.; Bratton, B. P.; Silhavy, T. J.; Wingreen, N. S.; Gitai, Z.; Wuhr, M.
10.1101/2022.08.01.502339 — systems biology — Posted on 2023-05-24
893 Vocal-visual combinations in wild chimpanzees
Mine, J. G.; Wilke, C.; Zulberti, C.; Bejhati, M.; Stoll, S.; Machanda, Z.; Manser, A.; Slocombe, K.; Townsend, S. W.
10.1101/2023.05.24.541909 — animal behavior and cognition — Posted on 2023-05-24
894 Fgf10 mutant newts can regenerate normal limbs despite severe developmental hindlimb defects
Suzuki, M.; Okumrura, A.; Shibata, Y.; Endo, T.; Teramoto, M.; Chihara, A.; Agata, K.; Bronner, M. E.; Suzuki, K.-i. T.
10.1101/2023.05.23.541496 — developmental biology — Posted on 2023-05-24
896 PKCδ regulates chromatin remodeling and DNA repair through SIRT6
Affandi, T.; Haas, A.; Ohm, A. M.; Wright, G. M.; Black, J. C.; Reyland, M. E.
10.1101/2023.05.24.541991 — molecular biology — Posted on 2023-05-24
898 LXR-inducible host E3 ligase IDOL targets a human cytomegalovirus reactivation determinant
Mlera, L.; Collins-McMillen, D. K.; Zeltzer, S.; Buehler, J.; Moy, M.; Zarrella, K.; Caviness, K.; Cicchini, L.; Tafoya, D. J.; Goodrum, F.
10.1101/2022.11.15.516687 — microbiology — Posted on 2023-05-24
899 Differential intra-host infection kinetics in Aedes aegypti underlie superior transmissibility of African relative to Asian Zika virus
Phengchat, R.; Pakparnich, P.; Pethrak, C.; Pengon, J.; Sartsanga, C.; Chotiwan, N.; Uppakara, K.; Suksirisawat, K.; Lambrechts, L.; Jupatanakul, N.
10.1101/2023.05.24.542190 — microbiology — Posted on 2023-05-24
901 Full-length single-cell BCR sequencing paired with RNA sequencing reveals convergent responses to vaccination
Morgan, D. M.; Zhang, Y.; Kim, J.-H.; Murillo, M.; Singh, S.; Loschko, J.; Surendran, N.; Patil, S. U.; Kanevsky, I.; Chorro, L.; Love, J. C.
10.1101/2023.05.23.541927 — immunology — Posted on 2023-05-24
902 A mechanistically novel peptide agonist of the IL-7 receptor that addresses limitations of IL-7 cytokine therapy
Dower, W. J.; Park, A. I.; Bakker, A. V.; Cwirla, S. E.; Pongtornpipat, P.; Williams, B. M.; Joshi, P.; Baxter, B. A.; Needels, M. C.; Barrett, R. W.
10.1101/2023.05.24.542196 — immunology — Posted on 2023-05-24
903 Cross-Protection Induced by Highly Conserved Human B, CD4+, and CD8+ T Cell Epitopes-Based Coronavirus Vaccine Against Severe Infection, Disease, and Death Caused by Multiple SARS-CoV-2 Variants of Concern
Prakash, S. F.; Dhanushkodi, N. R.; Zayou, L.; Ibraim, I. C.; Quadiri, A.; Coulon, P. G.; Tifrea, D. F.; Suzler, B.; Amin, M.; Chilukuri, A.; Edwards, R. A.; Vahed, H.; Nesburn, A. B.; Kuppermann, B. D.; Ulmer, J. B.; Gil, D.; Jones, T. M.; BenMohamed, L.
10.1101/2023.05.24.541850 — immunology — Posted on 2023-05-24
904 Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function
Thomas, R. M.; Pahl, M. C.; Wang, L.; Grant, S. F.; Hancock, W. W.; WELLS, A. D.
10.1101/2023.05.23.541951 — immunology — Posted on 2023-05-24
905 Pelvic irradiation induces behavioral and neuronal damage through gut dysbiosis in a rat model
Venkidesh, B. S.; Narasimhamurthy, R. K.; Jnana, A.; Reghunathan, D.; Sharan, K.; Chandraguthi, S. G.; Murali, T. S.; Mumbrekar, K. D.
10.1101/2023.05.21.541625 — neuroscience — Posted on 2023-05-24
907 Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer's disease.
Chartampila, E.; Elayouby, K. S.; Leary, P.; LaFrancois, J. J.; Alcantara-Gonzalez, D.; Jain, S.; Gerencer, K.; Botterill, J. J.; Ginsberg, S. D.; Scharfman, H.
10.1101/2023.05.12.540428 — neuroscience — Posted on 2023-05-24
909 Setdb1-loss induces type-I interferons and immune clearance of melanoma
McGeary, M. K.; Damsky, W.; Daniels, A.; Song, E.; Micevic, G.; Calderwood, C.; Lou, H. J.; Paradkar, S.; Kaech, S.; Calderwood, D. A.; Turk, B. E.; Iwasaki, A.; Bosenberg, M. W.
10.1101/2023.05.23.541922 — cancer biology — Posted on 2023-05-24
910 Human hnRNPA1 reorganizes telomere-bound Replication Protein A
Granger, S. L.; Sharma, R.; Kaushik, V.; Razzaghi, M.; Honda, M.; Bhat, D. S.; Wlodarski, M.; Antony, E.; Spies, M.
10.1101/2023.05.09.540056 — biophysics — Posted on 2023-05-24
913 Expansion of novel biosynthetic gene clusters from diverse environments using SanntiS
Sanchez Fragoso, J. S.; Rogers, J. D.; Rogers, A. B.; Nassar, M.; McEntyre, J.; Welch, M.; Hollfelder, F.; Finn, R. D.
10.1101/2023.05.23.540769 — bioinformatics — Posted on 2023-05-24
916 GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway
Hoppe, N.; Harrison, S.; Hwang, S.-H.; Chen, Z.; Karelina, M.; Deshpande, I.; Suomivuori, C.-M.; Palicharla, V. R.; Berry, S. P.; Tschaikner, P.; Regele, D.; Covey, D. F.; Stefan, E.; Marks, D. S.; Reiter, J.; Dror, R. O.; Evers, A. S.; Mukhopadhyay, S.; Manglik, A.
10.1101/2023.05.23.540554 — biochemistry — Posted on 2023-05-24
917 Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications
Singh, V.; Itoh, Y.; Del'Olio, S.; Hassan, A.; Naschberger, A.; Flygaard, R. K.; Nobe, Y.; Izumikawa, K.; Aibara, S.; Andrell, J.; Whitford, P.; Barrientos, A.; Taoka, M.; Amunts, A.
10.1101/2023.05.24.542018 — biochemistry — Posted on 2023-05-24
918 Telomere-to-telomere genome assembly of an allotetraploid pernicious weed, Echinochloa phyllopogon
Sato, M. P.; Iwakami, S.; Fukunishi, K.; Sugiura, K.; Yasuda, K.; Isobe, S.; Shirasawa, K.
10.1101/2023.05.23.541891 — genomics — Posted on 2023-05-24
919 Untangling an insect virome from its endogenous viral elements
Rozo-Lopez, P.; Brewer, W. T.; Kafer, S.; Martin, M. M.; Parker, B. J.
10.1101/2023.05.23.541933 — genomics — Posted on 2023-05-24
921 A primary microcephaly-associated sas-6 mutation perturbs centrosome duplication, dendrite morphogenesis, and ciliogenesis in Caenorhabditis elegans
Bergwell, M.; Smith, A.; Smith, E.; Dierlam, C.; Duran, R.; Haastrup, E.; Napier-Jameson, R.; Seidel, R.; Potter, W.; Norris, A.; Iyer, J.
10.1101/2022.11.25.518003 — genetics — Posted on 2023-05-24
925 Epidermal Eg5 promotes X-ROS dependent paclitaxel neurotoxicity
Diaz, A. C.; Cirrincione, A. M.; Schmidt, N. A.; Ugo, M. J.; Sanchez, M. C. A.; Reimonn, C. A.; Wuchty, S.; Pellegrini, A. D.; Rude, L. R.; Pappalardo, L. G.; Regan, D. P.; Howell, C.; Hrstka, S.; Dasari, S.; Lisse, T. S.; Harrison, B. J.; Xu, M. X.; Staff, N. P.; Rieger, S.
10.1101/2023.05.22.541784 — cell biology — Posted on 2023-05-24
926 EFA6R suppresses ovarian cancer cell migration and invasion
Tamaddon-Jahromi, S.; Murphy, K.; Walker, W.; Kanamarlapudi, V.
10.1101/2022.01.21.477266 — cell biology — Posted on 2023-05-24
929 TLK1-mediated RAD54 phosphorylation spatio-temporally regulates Homologous Recombination Repair
Ghosh, I.; Kwon, Y.; Badamchi Shabestari, A.; Chikhale, R.; Chen, J.; Wiese, C.; Sung, P.; DeBenedetti, A.
10.1101/2022.09.19.508551 — molecular biology — Posted on 2023-05-24
930 THE PALISADE LAYER OF THE POXVIRUS CORE IS COMPOSED OF FLEXIBLE A10-TRIMERS
Liu, J.; Corroyer-Dulmont, S.; Prazak, V.; Khusainov, I.; Bahrami, K.; Welsch, S.; Vasishtan, D.; Obarska-Kosinska, A.; Thorkelsson, S. R.; Grünewald, K.; Quemin, E. R. J.; Turonova, B.; Krijnse Locker, J.
10.1101/2023.05.24.542031 — molecular biology — Posted on 2023-05-24
932 The impact of RSV/SARS-CoV-2 co-infection on clinical disease and viral replication: insights from a BALB/c mouse model
Morris, D. R.; Qu, Y.; Thomason, K. S.; Haas de Mello, A.; Preble, R.; Menachery, V. D.; Casola, A.; Garofalo, R. P.
10.1101/2023.05.24.542043 — microbiology — Posted on 2023-05-24
933 A programmed response precedes cell lysis and death in a mat-forming cyanobacterium
Zorz, J.; Paquette, A. J.; Gillis, T.; Kouris, A.; Khot, V.; Demirkaya, C.; De La Hoz Siegler, H.; Strous, M.; Vadlamani, A.
10.1101/2022.10.17.512555 — microbiology — Posted on 2023-05-24
934 Inhibitors of cannabinoid receptor 1 suppress the cellular entry of Lujo virus
Kimura, M.; Matsuoka, R.; Taniguchi, S.; Maruyama, J.; Paessler, S.; Oka, S.; Yamashita, A.; Fukuhara, T.; Matsuura, Y.; Tani, H.
10.1101/2023.05.24.542186 — microbiology — Posted on 2023-05-24
935 Comparative electric and ultrastructural studies of cable bacteria reveal new components of conduction machinery
Digel, L.; Justesen, M. L.; Bonne, R.; Fransaert, N.; Wouters, K.; Jensen, P. B.; Plum-Jensen, L. E.; Marshall, I. P. G.; Nicolas-Asselineau, L.; Drace, T.; Boggild, A.; Hansen, J. L.; Schramm, A.; Bojesen, E. D.; Nielsen, L. P.; Manca, J. V.; Boesen, T.
10.1101/2023.05.24.541955 — microbiology — Posted on 2023-05-24
936 Inhibition of potassium ion channels reduces Semliki Forest virus genome replication
Russell, T.; O'Brien, C.; Gangotia, D.; Fulford, S.; Kenny, R.; Alkhamees, a.; Premchand-Branker, S.; Fragkoudis, R.; Scholz, D.; Barry, G.
10.1101/2023.05.24.541985 — microbiology — Posted on 2023-05-24
937 Direct mass spectrometry-based detection and antibody sequencing of Monoclonal Gammopathy of Undetermined Significance from patient serum - a case study.
Peng, W.; den Boer, M. A.; Tamara, S.; Mokiem, N. J.; van der Lans, S. P. A.; Schulte, D.; Haas, P.-J.; Minnema, M. C.; Rooijakkers, S. H. M.; van Zuilen, A. D.; Heck, A. J. R.; Snijder, J.
10.1101/2023.05.22.541697 — immunology — Posted on 2023-05-24
938 Establishment of CD1b-restricted immunity to lipid antigens in the pulmonary response to Mycobacterium tuberculosis infection
Harris, M. C.; Gary, H. E.; Cooper, S. K.; Ackart, D.; DiLisio, J. E.; Basaraba, R. J.; Cheng, T.-Y.; van Rhijn, I.; Moody, D. B.; Podell, B. K.
10.1101/2023.05.23.541963 — immunology — Posted on 2023-05-24
939 Helicobacter pylori attachment-blocking antibodies protect against duodenal ulcer disease
Boren, T.; Bugaytsova, J. A.; Moonens, K.; Piddubnyi, A.; Schmidt, A.; Edlund, J. O.; Lisiutin, G.; Brannstrom, K.; Chernov, Y. A.; Thorell, K.; Tkachenko, I.; Sharova, O.; Vikhrova, I.; Butsyk, A.; Shubin, P.; Chyzhma, R.; Johansson, D. X.; Marcotte, H.; Sjostrom, R.; Shevtsova, A.; Bylund, G.; Rakhimova, L.; Lundquist, A.; Berhilevych, O.; Kasianchuk, V.; Loboda, A.; Ivanytsia, V.; Hultenby, K.; Persson, M. A. A.; Gomes, J.; Matos, R.; Gartner, F.; Reis, C. A.; Whitmire, J. M.; Merrell, D. S.; Pan-Hammarstrom, Q.; Landstrom, M.; Oscarson, S.; DElios, M. M.; Agreus, L.; Ronkainen, J.; Aro, P.
10.1101/2023.05.24.542096 — immunology — Posted on 2023-05-24
940 Extracellular Delivery of Functional Mitochondria Rescues the Dysfunction of CD4+ T Cells in Aging.
Headley, C. A.; Gautam, S.; Olmo-Fontanez, A. M.; Garcia-Vilanova, A. M.; Dwivedi, V.; Akhter, A.; Schami, A.; Chiem, K.; Ault, R.; Zhang, H.; Cai, H.; Whigham, A. A.; Delgado, J. A.; Hicks, A. A.; Tsao, P.; Gelfond, J. A. L.; Martinez-Sobrido, L.; Wang, Y.; Torrelles, J. B.; Turner, J.
10.1101/2021.02.21.432151 — immunology — Posted on 2023-05-24
943 Functional Organization of Auditory and Reward Systems in Aging
Belden, A.; Quinci, M. A.; Geddes, M. R.; Hanser, S. B.; Donovan, N. J.; Loui, P.
10.1101/2023.01.01.522417 — neuroscience — Posted on 2023-05-24
945 Exploration of Mechanisms of Drug Resistance in a Microfluidic Device and Patient Tissues
Lim, W.; Hwang, I.; Zhang, J.; Chen, Z.; Han, J.; Jeon, J.; Koo, B.-K.; Kim, S.; Lee, J. E.; Pienta, K. J.; Amend, S. R.; Austin, R. H.; Ahn, J.-Y.; Park, S.
10.1101/2022.11.14.515727 — cancer biology — Posted on 2023-05-24
946 KAT5 regulates neurodevelopmental states associated with G0-like populations in glioblastoma
Mihalas, A.; Arora, S.; O'Connor, S.; Feldman, H.; Cucinotta, C. E.; Mitchell, K.; Bassett, J.; Kim, D.; Jin, K.; Hoellerbauer, P.; Delegard, J.; Ling, M.; Jenkins, W.; Kufeld, M.; Corrin, P.; Carter, L.; Tsukiyama, T.; Aronow, B. J.; Plaisier, C. J.; Patel, A.; PADDISON, P.
10.1101/2022.03.17.484768 — cancer biology — Posted on 2023-05-24
955 MISATO - Machine learning dataset for structure-based drug discovery
Siebenmorgen, T.; Menezes, F.; Benassou, S.; Merdivan, E.; Kesselheim, S.; Piraud, M.; Theis, F. J.; Sattler, M.; Popowicz, G. M.
10.1101/2023.05.24.542082 — bioinformatics — Posted on 2023-05-24
956 Integration of HLA-DR linkagedisequilibrium to MHC class II predictions
Boge Pedersen, M.; Rosenberg Asmussen, S.; Malou Sarfelt, F.; Brix Saksager, A.; Wad Sackett, P.; Nielsen, M.; Barra, C.
10.1101/2023.05.24.542040 — bioinformatics — Posted on 2023-05-24
959 THE PALISADE LAYER OF THE POXVIRUS CORE IS COMPOSED OF FLEXIBLE A10-TRIMERS
Liu, J.; Corroyer-Dulmont, S.; Prazak, V.; Khusainov, I.; Bahrami, K.; Welsch, S.; Vasishtan, D.; Obarska-Kosinska, A.; Thorkelsson, S. R.; Grünewald, K.; Quemin, E. R. J.; Turonova, B.; Krijnse Locker, J.
10.1101/2023.05.24.542031 — molecular biology — Posted on 2023-05-24
968 Cell cycle plasticity underlies fractional resistance to palbociclib in ER+/HER2- breast tumor cells
Zikry, T. M.; Wolff, S. C.; Ranek, J. S.; Davis, H.; Naugle, A.; Whitman, A. A.; Kosorok, M. R.; Spanheimer, P. M.; Purvis, J. E.
10.1101/2023.05.22.541831 — cancer biology — Posted on 2023-05-24
969 A pancreatic cancer mouse model with human immunity
Miyamura, N.; Suzuki, K.; Friedman, R. A.; Floratos, A.; Kunisada, Y.; Masuda, K.; Lowy, A. M.; Tsuji, M.; Sugahara, K. N.
10.1101/2023.05.24.542127 — cancer biology — Posted on 2023-05-24
970 Environmental stiffness restores mechanical homeostasis in vimentin-depleted cells
Grolleman, J.; Engeland, N. v.; Raza, M.; Azimi Rashti, S.; Conte, V.; Sahlgren, C.; Bouten, C.
10.1101/2023.05.23.541876 — biophysics — Posted on 2023-05-24
973 Environment and taxonomy shape the genomic signature of prokaryotic extremophiles
Millan Arias, P.; Butler, J.; Randhawa, G. S.; Soltysiak, M. P. M.; Hill, K. A.; Kari, L.
10.1101/2023.05.24.542097 — bioinformatics — Posted on 2023-05-24
975 PfAP2-MRP DNA-binding protein is a master regulator of parasite pathogenesis during malaria parasite blood stages
Pain, A.; Subudhi, A. K.; Green, J.; Satyam, R.; Lenz, T.; Salunke, R. P.; Shuaib, M.; Isaioglou, I.; Abel, S.; Gupta, M.; Esau, L.; Mourier, T.; Mfarrej, S.; Sivapurkar, R.; Stead, Z.; Ben-Rached, F.; Otswal, Y.; Sougrat, R.; Dada, A.; Kadamany, A. F.; Fishle, W.; Merzaban, J.; Knuepfer, E.; Ferguson, D. J. P.; Gupta, I.; Le Roch, K. G.; Holder, A. A.
10.1101/2023.05.23.541898 — genomics — Posted on 2023-05-24
978 Narwhal (Monodon monoceros) echolocation click rates to support cue counting passive acoustic density estimation
Marques, C. S.; Marques, D. A.; Blackwell, S. B.; Heide-Jorgensen, M. P. P.; Malinka, C. E.; Marques, T. A.
10.1101/2023.05.23.541771 — ecology — Posted on 2023-05-24
980 Liver Receptor Homolog-1 (LRH-1/NR5A2) orchestrates hepatic inflammation and TNF-induced cell death
Lambrecht, R.; Delgado, M. E.; Gloe, V.; Schuetz, K.; Plazzo, A. P.; Franke, B.; Phan, T. S.; Fleming, J. R.; Mayans, O.; Brunner, T.
10.1101/2023.05.24.542039 — cell biology — Posted on 2023-05-24
981 Group B Streptococcus Cas9 variants provide insight into programmable gene repression and CRISPR-Cas transcriptional effects
Gopalakrishna, K. P.; Hillebrand, G. H.; Bhavana, V. H.; Elder, J. L.; D'Mello, A.; Tettelin, H.; Hooven, T. A.
10.1101/2023.05.24.542094 — microbiology — Posted on 2023-05-24
983 Mesenchymal stem cells ameliorate inflammation in an experimental model of Crohn's disease via the mesentery
Dave, M.; Dev, A.; Somoza, R. A.; Zhao, N.; Viswanath, S.; Mina, P. R.; Chirra, P.; Obmann, V. C.; Mahabeleshwar, G. H.; Menghini, P.; Johnson, B. D.; Nolta, J. A.; Soto, C.; Osme, A.; Khuat, L. T.; Murphy, W.; Caplan, A. I.; Cominelli, F.
10.1101/2023.05.22.541829 — immunology — Posted on 2023-05-24
984 Multi-Scale Label-free Human Brain Imaging with Integrated Serial Sectioning Polarization Sensitive Optical Coherence Tomography and Two-Photon Microscopy
Chang, S.; Yang, J.; Novoseltseva, A.; Fu, X.; Li, C.; Chen, S.-C.; Augustinack, J. C.; Magnain, C.; Fischl, B.; McKee, A. C.; Boas, D. A.; Chen, I. A.; Wang, H.
10.1101/2023.05.22.541785 — neuroscience — Posted on 2023-05-24
986 Dorsal and median raphe neuronal firing dynamics characterized by non-linear metrics
Pascovich Rognoni, C.; Serantes, D.; Rodriguez, A.; Mateos, D. M.; Gonzalez, J.; Gallo, D.; Rivas, M.; Devera, A.; Lagos, P.; Rubido, N.; Torterolo, P.
10.1101/2023.05.23.541902 — neuroscience — Posted on 2023-05-24
990 PEP444c encoded within the MIR444c gene regulates microRNA444c accumulation in barley
Chojnacka, A.; Smoczynska, A.; Bielewicz, D.; Pacak, A.; Hensel, G.; Kumlehn, J.; Karlowski, W. M.; Grabsztunowicz, M.; Sobieszczuk-Nowicka, E.; Jarmolowski, A.; Szweykowska-Kulinska, Z.
10.1101/2023.05.24.542045 — plant biology — Posted on 2023-05-24
991 The adiponectin analogue ALY688-SR attenuates diaphragm fibrosis, atrophy and mitochondrial stress in a mouse model of Duchenne muscular dystrophy
Bellissimo, C. A.; Gandhi, S.; Castellani, L. N.; Murugathasan, M.; Delfinis, L. J.; Thuhan, A.; Garibotti, M. C.; Seo, Y.; Rebalka, I. A.; Sweeney, G.; Hawke, T. J.; Abdul-Sater, A. A.; Perry, C. G.
10.1101/2023.05.22.541826 — physiology — Posted on 2023-05-24
993 CCR9 overexpression promotes T-ALL progression by enhancing cholesterol biosynthesis
Jamal, M.; Lei, Y.; He, H.; Zeng, X.; Wei, Z.; Xiao, D.; Liang, S.; Zhou, F.; Zhang, Q.
10.1101/2023.05.24.542034 — cancer biology — Posted on 2023-05-24
996 Modulation of functional phosphorylation sites by basic residues in the Unique domain of c-Src
Lang, A.; Fernandez, A.; Diaz-Lobo, M.; Vilanova, M.; Cardenas, F.; Gairi, M.; Pons, M.
10.1101/2023.05.23.541872 — biophysics — Posted on 2023-05-24
998 The Structural Role of N170 in Substrate-assisted Deacylation in KPC-2 β-Lactamase
Parwana, D.; Gu, J.; Wang, Q.; Bethel, C.; Marshall, E. K.; Hujer, A. M.; Bonomo, R. A.; Haider, S.
10.1101/2023.05.22.541848 — biophysics — Posted on 2023-05-24
999 Design of optimal labeling patterns for optical genome mapping via information theory
Nogin, Y.; Bar-Lev, D.; Hanania, D.; Detinis Zur, T.; Ebenstein, Y.; Yaakobi, E.; Weinberger, N.; Shechtman, Y.
10.1101/2023.05.23.541882 — bioinformatics — Posted on 2023-05-24
1004 AlphaFold2 captures the conformational landscape of the HAMP signaling domain
Winski, A.; Ludwiczak, J.; Orlowska, M.; Madaj, R.; Kaminski, K.; Dunin-Horkawicz, S.
10.1101/2023.05.23.541686 — bioinformatics — Posted on 2023-05-24
1008 Construction and optimization of multi-platform precision pathways for precision medicine
Tran, A.; Wang, A.; Mickaill, J.; Strbenac, D.; Larance, M.; Vernon, S.; Grieve, S.; Figtree, G.; Patrick, E.; Yang, J. Y. H.
10.1101/2023.05.23.541873 — bioinformatics — Posted on 2023-05-24
1009 Sound-based assembly of three-dimensional cellularized and acellularized constructs
Tognato, R.; Parolini, R.; Alini, M.; Richards, R. G.; Ma, J.; Jahangir, S.; Florczak, S.; Levato, R.; Serra, T.
10.1101/2023.05.23.541870 — bioengineering — Posted on 2023-05-24
1010 Characterizing glucokinase variant mechanisms using a multiplexed abundance assay
Gersing, S.; Schulze, T. K.; Cagiada, M.; Stein, A.; Roth, F. P.; Lindorff-Larsen, K.; Hartmann-Petersen, R.
10.1101/2023.05.24.542036 — biochemistry — Posted on 2023-05-24
1011 Identification of the Intracellular Protein Targets of a Bio-active Clickable Half-Sandwich Iridium Complex by Chemical Proteomics
Ramos, R.; Karaiskou, A.; Botuha, C.; Trichet, M.; Dingli, F.; Forte, J.; Lam, F.; Canette, A.; Chaumeton, C.; Salome, M.; Chenuel, T.; Bergonzi, C.; Meyer, P.; Bohic, S.; Loew, D.; Salmain, M.; Sobczak-Thepot, J.
10.1101/2023.05.24.542041 — biochemistry — Posted on 2023-05-24
1012 Mitochondrial temperature homeostasis resists external metabolic stresses
Terzioglu, M.; Veeroja, K.; Montonen, T.; Ihalainen, T. O.; Salminen, T. S.; Benit, P.; Rustin, P.; Chang, Y.-T.; Takeharu, N.; Jacobs, H. T.
10.1101/2023.05.24.542069 — biochemistry — Posted on 2023-05-24
1020 Shortcut barcoding and early pooling for scalable multiplex single-cell reduced-representation CpG methylation sequencing at single nucleotide resolution
Mai, L.; Wen, Z.; Zhang, Y.; Gao, Y.; Lin, G.; Lian, Z.; Yang, X.; Zhou, J.; Lin, X.; Luo, C.; Peng, W.; Chen, C.; Liu, D.; Zhang, J.; Marjani, S. L.; Tao, Q.; Wu, X.; Weissman, S. M.; Pan, X.
10.1101/2023.05.22.541674 — genomics — Posted on 2023-05-24
1021 Inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative manner.
Shao, Z.; Lee, B. J.; Zhang, H.; Lin, X.; Li, C.; Jiang, W.; Chirathivat, N.; Gershik, S.; Shen, M. M.; Baer, R.; Zha, S.
10.1101/2023.05.23.542022 — genetics — Posted on 2023-05-24
1023 On the cusp of adaptive change: the hierarchical radiation of phyllostomid bats
Grossnickle, D. M.; Sadier, A. A.; Patterson, E.; Cortes-Viruet, N. N.; Jimenez Rivera, S.; Sears, K. E.; Santana, S.
10.1101/2023.05.23.541856 — evolutionary biology — Posted on 2023-05-24
1024 Spatio-temporal variation of bacterial community structure in two intertidal sediment types of Jiaozhou Bay
Chen, X.; Zhang, X.; Yu, H.; Han, M.; Sun, J.; Liu, G.; Ji, Y.; Zhai, C.; Zhu, L.; Shao, H.; Liang, Y.; McMinn, A.; Wang, M.
10.1101/2023.05.24.542048 — ecology — Posted on 2023-05-24
1026 Building the vector in? Construction practices contribute to the invasion and persistence of Anopheles stephensi in Jigjiga, Ethiopia
Yared, S.; Gebresilassie, A.; Aklilu, E.; Abdulahi, E.; Kirstein, O. D.; Gonzalez-Olvera, G.; Che-Mendoza, A.; Bibiano-Marin, W.; Waymire, E.; Lines, J.; Lenhart, A.; Kitron, U.; Carter, T.; Manrique-Saide, P.; Vazquez-Prokopec, G.
10.1101/2023.05.23.541906 — ecology — Posted on 2023-05-24
1027 Evolutionary conservation of embryonic DNA methylome remodelling in distantly related teleost species
Ross, S. E.; Vazquez-Marin, J.; Gert, K. R. B.; Gonzalez-Rajal, A.; Dinger, M. E.; Pauli, A.; Martinez-Morales, J. R.; Bogdanovic, O.
10.1101/2023.05.24.542066 — developmental biology — Posted on 2023-05-24
1031 Development and validation of a high throughput screening platform to enable target identification in skeletal muscle cells from Duchenne Muscular Dystrophy (DMD) patients
Hariharan, S.; Lorintiu, O.; Lee, C. W.; Duchemin-Pelletier, E.; Li, X.; Healy, A.; Doyonnas, R.; Selig, L.; Poydenot, P.; Ventre, E.; Weston, A.; Owens, J.; Christoforou, N.
10.1101/2023.05.24.542079 — cell biology — Posted on 2023-05-24
1032 Analysis of cortical cell polarity by imaging flow cytometry
Jespersen, J. H.; Harazin, A.; Bohn, A. B.; Christensen, A.; Lorentzen, E.; Lorentzen, A.
10.1101/2023.05.24.542074 — cell biology — Posted on 2023-05-24
1033 Antibiotic prophylaxis and hospitalization of horses subjected to median laparotomy: gut microbiota trajectories and abundance increase of Escherichia
Kauter, A.; Brombach, J.; Luebke-Becker, A.; Kannapin, D.; Bang, C.; Franzenburg, S.; Stoeckle, S. D.; Mellmann, A.; Effelsberg, N.; Koeck, R.; Guenther, S.; Wieler, L. H.; Gehlen, H.; Semmler, T.; Wolf, S. A.; Walther, B.
10.1101/2023.05.24.542119 — microbiology — Posted on 2023-05-24
1036 All-optical interrogation of brain-wide activity in freely swimming larval zebrafish
Chai, Y.; Qi, K.; Wu, Y.; Li, D.; Tan, G.; Guo, Y.; Chu, J.; Mu, Y.; Shen, C.; Wen, Q.
10.1101/2023.05.24.542114 — neuroscience — Posted on 2023-05-24
1037 ATP-Gated Potassium Channels Contribute to Ketogenic Diet-Mediated Analgesia in Mice.
Enders, J. D.; Thomas, S.; Lynch, P.; Jack, J.; Ryals, J.; Puchalska, P.; Crawford, P. A.; Wright, D. E.
10.1101/2023.05.22.541799 — neuroscience — Posted on 2023-05-24
1042 Interaction of multiple future movement plans in sequential reaching
Kashefi, M.; Reschechtko, S.; Ariani, G.; Shahbazi, M.; Diedrichsen, J.; Pruszynski, J. A.
10.1101/2023.05.24.542099 — neuroscience — Posted on 2023-05-24
1045 Comparison of histological delineations of medial temporal lobe cortices by four independent neuroanatomy laboratories
Wuestefeld, A.; Baumeister, H.; Adams, J. N.; de Flores, R.; Hodgetts, C.; Mazloum-Farzaghi, N.; Olsen, R. K.; Puliyadi, V.; Tran, T. T.; Bakker, A.; Canada, K. L.; Dalton, M. A.; Daugherty, A. M.; La Joie, R.; Wang, L.; Bedard, M.; Buendia, E.; Denning, A.; Irwin, D. J.; Ittyerah, R.; Lee, E. B.; Lim, S.; Iniguez de Onzono Martin, M. M.; Munoz Lopez, M.; Schuck, T.; Trotman, W.; Vela, A.; Yushkevich, P.; Amunts, K.; Augustinack, J. C.; Ding, S.-L.; Insausti, R.; Kedo, O.; Berron, D.; Wisse, L. E. M.
10.1101/2023.05.24.542054 — neuroscience — Posted on 2023-05-24
1051 A genome catalog of the early-life human skin microbiome
Shen, Z.; Robert, L.; Stolpman, M.; Che, Y.; Walsh, A.; Saffery, R.; Allen, K. J.; Eckert, J.; Young, A.; Deming, C.; Chen, Q.; Conlan, S.; Laky, K.; Li, J. M.; Chatman, L.; Kashaf, S. S.; NISC Comparative Sequencing Program, ; VITALITY team, ; Kong, H. H.; Frischmeyer-Guerrerio, P. A.; Perrett, K. P.; Segre, J. A.
10.1101/2023.05.22.541509 — genomics — Posted on 2023-05-24
1054 Novel TRPM7 inhibitors with potent anti-inflammatory effects in vivo
Busey, G. W.; Manjegowda, M. C.; Huang, T.; Iobst, W. H.; Naphade, S. S.; Kennedy, J. A.; Doyle, C. A.; Seegren, P. V.; Lynch, K. R.; Desai, B. N.
10.1101/2023.05.22.541802 — immunology — Posted on 2023-05-24
1056 Reduction of retinal ganglion cell death in mouse models of familial dysautonomia using AAV-mediated gene therapy and splicing modulators
Schultz, A.; Cheng, S.-Y.; Kirchner, E.; Costello, S.; Miettinen, H.; Chaverra, M.; King, C.; George, L.; Zhao, X.; Narasimhan, J.; Weetall, M.; Slaugenhaupt, S.; Morini, E.; Punzo, C.; Lefcort, F.
10.1101/2023.05.22.541535 — neuroscience — Posted on 2023-05-24
1060 Acute resistance exercise induces mitophagy and mitophagomes on subsarcolemmal clefts in human skeletal muscle: Focus on BNIP3L/NIX40 as a mitophagy flux marker
Diaz-Castro, F.; Tunon-Suarez, M.; Quezada, N.; Rivera, P.; Cancino, J.; Zbinden-Foncea, H.; Morselli, E.; Castro-Sepulveda, M.
10.1101/2023.05.22.541782 — physiology — Posted on 2023-05-24
1064 A CRISPR-induced DNA break can trigger crossover, chromosomal loss and chromothripsis-like rearrangements
Samach, A.; Mafessoni, F.; Gross, O.; Melamed-Bessudo, C.; Filler Hayut, S.; Dahan-Meir, T.; Amsellem, Z.; Pawlowski, W. P.; Levy, A. A.
10.1101/2023.05.22.541757 — genetics — Posted on 2023-05-24
1066 Compression strategies for large-scale electrophysiology data
Buccino, A. P.; Winter, O.; Bryant, D.; Feng, D.; Svoboda, K.; Siegle, J. H.
10.1101/2023.05.22.541700 — neuroscience — Posted on 2023-05-24
1071 Dissecting endocytic mechanisms reveals new molecular targets to enhance sodium iodide symporter activity with clinical relevance to radioiodide therapy
Read, M. L.; Brookes, K.; Zha, L.; Manivannan, S.; Kim, J.; Kocbiyik, M.; Fletcher, A.; Gorvin, C. M.; Firth, G.; Fruhwirth, G. O.; Nicola, J. P.; Jhiang, S.; Ringel, M. D.; Campbell, M. J.; Sunassee, K.; Blower, P. J.; Boelaert, K.; Nieto, H. R.; Smith, V. E.; McCabe, C. J.
10.1101/2023.05.22.541733 — cancer biology — Posted on 2023-05-24
1073 pH-responsive upconversion mesoporous silica nanospheres for combined multimodal diagnostic imaging and targeted photodynamic and photothermal cancer therapy
Palanikumar, L.; Kalmouni, M.; Houhou, T.; Abdullah, O.; Ali, L.; Pasricha, R.; Thomas, S.; Afzal, A.; Barrera, F. N.; Magzoub, M.
10.1101/2023.05.22.541491 — bioengineering — Posted on 2023-05-24
1076 Imputation Efficacy Across Global Human Populations
Cahoon, J. L.; Rui, X.; Tang, E.; Simons, C.; Langie, J.; Chen, M.; Lo, Y.-C.; Chiang, C. W. K.
10.1101/2023.05.22.541241 — genetics — Posted on 2023-05-24
1080 Synchrony of Bird Migration with Avian Influenza Global Spread; Implications for Vulnerable Bird Orders
Yang, Q.; Wang, B.; Lemey, P.; Dong, L.; Mu, T.; Wiebe, R. A.; Guo, F.; Trovao, N. S.; Park, S. W.; Lewis, N.; Tsui, J.; Bajaj, S.; Cheng, Y.; Yang, L.; Haba, Y.; Li, B.; Zhang, G.; Pybus, O. G.; Tian, H.; Grenfell, B. T.
10.1101/2023.05.22.541648 — ecology — Posted on 2023-05-24
1081 Basolateral Amygdala Corticotrophin Releasing Factor Receptor 2 Interacts with Nonmuscle Myosin II to Destabilize Memory
Hafenbreidel, M.; Briggs, S. B.; Arza, M.; Bonthu, S.; Fisher, C.; Tiller, A.; Hall, A. B.; Reed, S.; Mayorga, N.; Lin, L.; Khan, S.; Cameron, M. D.; Rumbaugh, G.; Miller, C. A.
10.1101/2023.05.22.541732 — neuroscience — Posted on 2023-05-24
1083 Rational screening for cooperativity in small-molecule inducers of protein-protein associations
Liu, S.; Tong, B.; Mason, J. W.; Ostrem, J. M.; Tutter, A.; Hua, B. K.; Tang, S. A.; Bonazzi, S.; Briner, K.; Berst, F.; Zecri, F. J.; Schreiber, S. L.
10.1101/2023.05.22.541439 — biophysics — Posted on 2023-05-24
1085 Structural principles of peptide-centric Chimeric Antigen Receptor recognition guide therapeutic expansion
Sun, Y.; Florio, T. J.; Gupta, S.; Young, M. C.; Marshall, Q. F.; Garfinkle, S. E.; Papadaki, G. F.; Truong, H. V.; Mycek, E.; Li, P.; Farrel, A.; Church, N. L.; Jabar, S.; Beasley, M. D.; Kiefel, B. R.; Yarmarkovich, M.; Mallik, L.; Maris, J. M.; Sgourakis, N. G.
10.1101/2023.05.24.542108 — biochemistry — Posted on 2023-05-24
1088 Multiple mechanisms contribute to isolation-by-environment in the redheaded pine sawfly, Neodiprion lecontei
Bagley, R. K.; Hurst, M. N.; Frederick, J.; Wolfe, J.; Terbot, J. W.; Frost, C. J.; Linnen, C. R.
10.1101/2023.05.22.541587 — evolutionary biology — Posted on 2023-05-24
1091 Bat cellular immunity varies by year and dietary habit in an increasingly fragmented landscape
DeAnglis, I. K.; Andrews, B. R.; Lock, L. R.; Dyer, K. E.; Volokhov, D. V.; Fenton, M. B.; Simmons, N. B.; Downs, C. J.; Becker, D. J.
10.1101/2023.05.22.541709 — ecology — Posted on 2023-05-24
1097 Toxins in plastic: Evidence for the cardiodepressive effects of di-2-ethylhexylphthalate (DEHP)
Swift, L. M.; Roberts, A.; Pressman, J.; Guerrelli, D.; Allen, S.; Haq, K.; Reisz, J.; D'Alessandro, A.; Posnack, N. G.
10.1101/2023.05.22.541729 — pharmacology and toxicology — Posted on 2023-05-24
1098 H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours
Dibitetto, D.; Liptay, M.; Vivalda, F.; Gogola, E.; Dogan, H.; Fernandez, M. G.; Duarte, A.; Schmid, J. A.; Durant, S. T.; Forment, J. V.; Klebic, I.; Siffert, M.; de Brujin, R.; Kousholt, A. N.; Marti, N. A.; Dettwiler, M.; Sorensen, C. S.; Lopes, M.; Sartori, A. A.; Jonkers, J.; Rottenberg, S.
10.1101/2023.05.22.541781 — cancer biology — Posted on 2023-05-24
1099 Inflammation in the COVID-19 airway is due to inhibition of CFTR signaling by the SARS-CoV-2 Spike protein
Caohuy, H.; Eidelman, O.; Chen, T.; Yang, Q.; Pollard, B. S.; Walton, N. I.; Pollard, H. B.
10.1101/2022.01.18.476803 — microbiology — Posted on 2023-05-24
1103 Evolutionary rescue and reintroduction of resistant frogs allows recovery in the presence of a lethal fungal disease
Knapp, R. A.; Wilber, M. Q.; Byrne, A. Q.; Joseph, M. B.; Smith, T. C.; Rothstein, A. P.; Grasso, R. L.; Rosenblum, E. B.
10.1101/2023.05.22.541534 — ecology — Posted on 2023-05-24
1105 The transcription factor bZIP11 acts antagonistically with trehalose 6-phosphate to inhibit shoot branching
Hellens, A.; Kreisz, P.; Humphreys, J. L.; Feil, R.; Lunn, J. E.; Droge-Laser, W.; Beveridge, C. A.; Fichtner, F.; Weiste, C.; Barbier, F. F.
10.1101/2023.05.23.542007 — plant biology — Posted on 2023-05-24
1106 S1 basic leucine zipper transcription factors shape plant architecture by controlling C/N partitioning to apical and lateral organs
Kreisz, P.; Hellens, A. M.; Froeschel, C.; Krischke, M.; Maag, D.; Feil, R.; Wildenhain, T.; Draken, J.; Braune, G.; Erdelitsch, L.; Cecchino, L.; Wagner, T. C.; Mueller, M. J.; Becker, D.; Lunn, J. E.; Hanson, J.; Beveridge, C. A.; Fichtner, F.; Barbier, F. F.; Weiste, C.
10.1101/2023.05.23.541964 — plant biology — Posted on 2023-05-24
1108 Transposon dynamics in the emerging oilseed crop Thlaspi arvense
Contreras-Garrido, A.; Galanti, D.; Movilli, A.; Becker, C.; Bossdorf, O.; Drost, H.-G.; Weigel, D.
10.1101/2023.05.24.542068 — genomics — Posted on 2023-05-24
1110 Direct mass spectrometry-based detection and antibody sequencing of Monoclonal Gammopathy of Undetermined Significance from patient serum - a case study.
Peng, W.; den Boer, M. A.; Tamara, S.; Mokiem, N. J.; van der Lans, S. P. A.; Schulte, D.; Haas, P.-J.; Minnema, M.; Rooijakkers, S. H. M.; van Zuilen, A. D.; Heck, A. J. R.; Snijder, J.
10.1101/2023.05.22.541697 — immunology — Posted on 2023-05-24
1112 EEG resting state alpha dynamics predict individual proneness to auditory hallucinations
Honcamp, H.; Duggirala, S. X.; Rodino Climent, J.; Astudillo, A.; Trujillo-Barreto, N. J.; Schwartze, M.; Linden, D. E. J.; Amelsvoort, T.; El-Deredy, W.; Kotz, S. A.
10.1101/2023.05.22.541696 — neuroscience — Posted on 2023-05-24
1113 Age-related phenotypes in breast cancer: a population- based study
Svanoe, A.; Humlevik, R.; Knutsvik, G.; Sele, A. K. M.; Askeland, C.; Ingebriktsen, L. M.; Hugaas, U.; Kvamme, A. B.; Tegnander, A. F.; Kruger, K.; Davidsen, B.; Hoivik, E. A.; Aas, T.; Stefansson, I. M.; Akslen, L. A.; Wik, E.
10.1101/2023.05.22.541427 — pathology — Posted on 2023-05-24
1116 Disease associated human TCR characterization by deep-learning framework TCR-DeepInsight
Xue, Z.; Wu, L.; Tian, R.; Liu, Z.; Bai, Y.; Sun, D.; Guo, Y.; Chen, P.; Zhao, Y.; He, B.; Wang, L.; Yao, J.; Lu, L.; Liu, W.
10.1101/2023.05.22.541406 — bioinformatics — Posted on 2023-05-24
1117 GASOLINE: detecting germline and somatic structural variants from long-reads data.
Magi, A.; Mattei, G.; Mingrino, A.; Caprioli, C.; Ronchini, C.; Frige, G.; Semeraro, R.; Bolognini, D.; Colombo, E.; Mazzarella, L.; Pelicci, P. G.
10.1101/2023.05.22.541558 — bioinformatics — Posted on 2023-05-24
1119 Ensemble of deep learning language models to support the creation of living systematic reviews for the COVID-19 literature
Knafou, J.; Haas, Q.; Borissov, N.; Counotte, M. J.; Low, N.; Imeri, H.; Ipekci, A. M.; Buitrago-Garcia, D.; Heron, L.; Amini, P.; Teodoro, D.
10.1101/2023.01.18.524571 — bioinformatics — Posted on 2023-05-24
1123 Disrupted memory T cell expansion in HIV-exposed uninfected infants is preceded by premature skewing of T cell receptor clonality.
Dzanibe, S.; Wilk, A. J.; Canny, S.; Ranganath, T.; Alinde, B.; Rubelt, F.; Huang, H.; Davis, M.; Holmes, S. P.; Jaspan, H. B.; Blish, C. A.; Gray, C. M.
10.1101/2023.05.19.540713 — immunology — Posted on 2023-05-24
1127 The transcription factor OsbZIP48 governs rice responses to zinc deficiency
Zheng, L.; Hu, S.; Du, B.; Mu, G.; jiang, Z.; Li, H.; Song, Y.; Zhang, B.; Xia, J.; Rouached, H.
10.1101/2023.05.18.541251 — plant biology — Posted on 2023-05-24
1128 H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in paediatric high-grade glioma cells
Leszczynska, K. B.; Pereira de Freitas, A.; Jayaprakash, C.; Dzwigonska, M.; Wojnicki, K.; Gielniewski, B.; Szadkowska, P.; Kaza, B.; Ciolkowski, M. K.; Trubicka, J.; Grajkowska, W.; Kaminska, B.; Mieczkowski, J.
10.1101/2023.05.15.540760 — cancer biology — Posted on 2023-05-24
1130 Has recombination changed during the recent evolution of the guppy Y chromosome?
Charlesworth, D.; Qiu, S.; Bergero, R.; Gardner, J.; Keegan, K.; Konczal, M.
10.1101/2023.05.17.541215 — genetics — Posted on 2023-05-24
1131 P53 and BCL-2 family proteins PUMA and NOXA define competitive fitness in Pluripotent Cells
Valverde, J. A.; Li-Bao, L.; Diaz-Diaz, C.; Sierra, R.; Santos, E.; Giovinazo, G.; Torres, M.
10.1101/2023.05.21.541667 — developmental biology — Posted on 2023-05-24
1132 ChAdOx1 COVID vaccines express RBD open prefusion SARS-CoV-2 spikes on the cell surface
Zhang, P.; Gilbert, S.; Radecke, J.; Ni, T.; Mendonca, L.; Zhu, Y.; Howe, A.; Shah, P. M.; Sheng, Y.; Krebs, A.-S.; Duyvesteyn, H. M. E.; Allen, E.; Lambe, T.; Bissett, C.; Morris, S.; Spencer, A.; Stuart, D. I.
10.1101/2023.05.22.541685 — microbiology — Posted on 2023-05-24
1133 Functional and metagenomic level diversities of human gut symbiont-derived glycolipids
Yoo, J.-S.; Goh, B.; Heo, K.; Jung, D.-J.; Zheng, W.; Lee, C. C.; Geva-Zatorsky, N.; Wu, M.; Park, S. B.; Kasper, D. L.; Oh, S. F.
10.1101/2023.05.23.541633 — microbiology — Posted on 2023-05-24
1134 Generation of a Plasmodium falciparum reporter line for studies of parasite biology throughout the life cycle
Suarez-Cortes, P.; Costa, G.; Andres, M.; Eyermann, D.; Kreschel, C.; Spohr, L.; Goosmann, C.; Brinkmann, V.; Levashina, E. A.
10.1101/2023.05.23.542002 — microbiology — Posted on 2023-05-24
1142 Characterizing fibrinolysis under flow conditions: a simplified mesoscale 3D model
Petkantchin, R.; Rousseau, A.; Eker, O.; Boudjeltia, K. Z.; Raynaud, F.; Chopard, B.
10.1101/2023.05.09.539942 — biophysics — Posted on 2023-05-24
1143 Assisting and Accelerating NMR Assignment with Restrained Structure Prediction
Liu, S.; Chu, H.; Xie, Y.; Wu, F.; Ni, N.; Wang, C.; Mu, F.; Wei, J.; Zhang, J.; Chen, M.; Li, J.; Yu, F.; Fu, H.; Wang, S.; Tian, C.; Wang, Z.; Gao, Y. Q.
10.1101/2023.04.14.536890 — bioinformatics — Posted on 2023-05-24
1145 High-throughput phenotyping of single nucleotide variants by linking transcriptomes to genotypes in single cells
Cooper, S. E.; Coelho, M. A.; Strauss, M. E.; Gontarczyk, A. M.; Wu, Q.; Garnett, M. J.; Marioni, J.; Bassett, A. R.
10.1101/2023.05.22.541777 — genetics — Posted on 2023-05-24
1147 Epitranscriptomics m6A analyses reveal distinct m6A marks under tumor necrosis α (TNF-α)-induced apoptotic conditions in HeLa cells
Alasar, A. A.; Tuncel, O.; Saglam, B.; Gazaloglu, Y.; Atbinek, M.; Cagiral, U.; Iscan, E.; Ozhan, G.; Akgul, B.
10.1101/2023.05.20.541583 — cell biology — Posted on 2023-05-24
1150 Age-maintained human neurons demonstrate a developmental loss of intrinsic neurite growth ability
Lear, B. P.; Thompson, E. A. N.; Rodriguez, K.; Arndt, Z. P.; Khullar, S.; Klosa, P. C.; Lu, R. J.; Morrow, C. S.; Risgaard, R.; Peterson, E. R.; Teefy, B. B.; Bhattacharyya, A.; Sousa, A. M. M.; Wang, D.; Benayoun, B. A.; Moore, D. L.
10.1101/2023.05.23.541995 — neuroscience — Posted on 2023-05-24
1154 Mechanistic target of rapamycin (mTOR) pathway in Sertoli cells regulates age-dependent changes in sperm DNA methylation
Amir, S.; Arowolo, O.; Mironova, E.; McGaunn, J.; Oluwayiose, O.; Sergeyev, O.; Pilsner, J. R.; Suvorov, A.
10.1101/2023.05.23.541978 — developmental biology — Posted on 2023-05-23
1155 Tight junctions regulate lumen morphology via hydrostatic pressure and junctional tension
Mukenhirn, M.; Wang, C.-H.; Guyomar, T.; Bovyn, M. J.; Staddon, M. F.; Maraspini, R.; Lu, L.; Martin-Lemaitre, C.; Sano, M.; Hiraiwa, T.; Riveline, D.; Honigmann, A.
10.1101/2023.05.23.541893 — cell biology — Posted on 2023-05-23
1157 Real Time In vivo Analysis of Pancreatic Beta-cell Autophagic Flux Reveals Impairment Before Onset of Autoimmune Diabetes
Melnyk, O.; Muralidharan, C.; Duffett, B.; Novak, A. N.; Perez-Aviles, G.; Martinez, M. M.; Crowder, J. J.; Linnemann, A. K.
10.1101/2023.05.23.541935 — cell biology — Posted on 2023-05-23
1159 Cardiomyocyte-restricted expression of IL11 causes cardiac fibrosis, inflammation, and dysfunction.
Sweeney, M. D.; O'Fee, K.; Villanueva-Hayes, C.; Rahman, E.; Lee, M.; Andrew, I.; Vanezis, K.; Lim, W.-W.; Widjaja, A. A.; Barton, P. J.; Cook, S. A.
10.1101/2023.05.23.541928 — molecular biology — Posted on 2023-05-24
1162 Cardiomyocyte-restricted expression of IL11 causes cardiac fibrosis, inflammation, and dysfunction.
Sweeney, M. D.; O'Fee, K.; Villanueva-Hayes, C.; Rahman, E.; Lee, M.; Andrew, I.; Vanezis, K.; Lim, W.-W.; Widjaja, A. A.; Barton, P. J.; Cook, S. A.
10.1101/2023.05.23.541928 — molecular biology — Posted on 2023-05-23
1165 Ecological monitoring using Collembola metabarcoding with extremely low bycatch amplification.
Pedro, P. M.; Cullen, L.; Prado, F.; Uezu, A.; Piper, R.; Faria, C.; Knogge, C.; Razzolini, M. T.; Paiva, M.; Dropa, M.; Silva, M.; Rech, T.; Thomas, P.
10.1101/2023.05.23.541478 — molecular biology — Posted on 2023-05-23
1166 Proteasomal regulation of ASK family kinases dictates cell fate under hyperosmotic stress
Zhou, X.; Watanabe, K.; Morishita, K.; Hamazaki, J.; Murata, S.; Naguro, I.; Ichijo, H.
10.1101/2023.05.23.541899 — molecular biology — Posted on 2023-05-23
1169 Cataloging the Phylogenetic Diversity of Human Bladder Bacterial Isolates
Wolfe, A.; Du, J.; Khemmani, M.; Halverson, T.; Ene, A.; Limeira, R.; Tinawi, L.; Hochstedler-Kramer, B. R.; Noronha, M. F.; Putonti, C.
10.1101/2023.05.23.541916 — microbiology — Posted on 2023-05-23
1170 Functional and metagenomic level diversities of human gut symbiont-derived glycolipids
Oh, S. F.; Yoo, J.-S.; Goh, B.; Heo, K.; Jung, D.-J.; Zheng, W.; Lee, C. C.; Geva-Zatorsky, N.; Wu, M.; Park, S. B.; Kasper, D. L.
10.1101/2023.05.23.541633 — microbiology — Posted on 2023-05-23
1172 Mapping Niche-specific Two-Component System Requirements in Uropathogenic Escherichia coli
Brannon, J. R.; Reasoner, S.; Bermudez, T.; Dunigan, T. L.; Wiebe, M. A.; Beebout, C. J.; Ross, T. L.; Bamidele, A.; Hadjifrangiskou, M.
10.1101/2023.05.23.541942 — microbiology — Posted on 2023-05-23
1174 Simultaneous carbon catabolite repression governs sugar and aromatic co-utilization in Pseudomonas putida M2
Shrestha, S.; Awasthi, D.; Chen, Y.; Gin, J. W.; Petzold, C. J.; Adams, P. D.; Simmons, B. A.; Singer, S.
10.1101/2023.05.23.541960 — microbiology — Posted on 2023-05-23
1175 The carbapenem inoculum effect provides insight into the molecular mechanisms underlying carbapenem resistance in Enterobacterales
Cartagena, A. J.; Taylor, K. L.; Smith, J. T.; Manson, A. L.; Earl, A. M.; Pierce, V. M.; Bhattacharyya, R. P.
10.1101/2023.05.23.541813 — microbiology — Posted on 2023-05-23
1176 A Standardized Antiviral Pipeline for Human Norovirus in Human Intestinal Enteroids Demonstrates No Antiviral Activity of Nitazoxanide
Lewis, M. A.; Cortes-Penfield, N. W.; Ettayebi, K.; Patil, K.; Kaur, G.; Neill, F. H.; Atmar, R. L.; Ramani, S.; Estes, M. K.
10.1101/2023.05.23.542011 — microbiology — Posted on 2023-05-23
1179 Ferroptosis induced by phenolic compound-iron complex
Sui, X.; Wang, J.; Zhao, Z.; Liu, B.; Liu, M.; Liu, M.; Shi, C.; Feng, X.; Fu, Y.; Shi, D.; Li, S.; Qi, Q.; Xian, M.; Zhao, G.
10.1101/2023.05.23.541885 — microbiology — Posted on 2023-05-23
1180 Live tracking of a plant pathogen outbreak reveals rapid and successive, multidecade episome reduction
Roman-reyna, V.; Sharma, A.; Toth, H.; Konkel, Z.; Omiotek, N.; Murthy, S.; Faith, S.; Slot, J.; Hand, F. P.; Goss, E.; Jacobs, J. M.
10.1101/2023.05.23.541994 — microbiology — Posted on 2023-05-23
1181 Accelerated prime-and-trap vaccine regimen in mice using repRNA-based CSP malaria vaccine
MacMillen, Z.; Hatzakis, K.; Simpson, A.; Shears, M. J.; Watson, F.; Erasmus, J.; Khandhar, A. P.; Wilder, B. K.; Murphy, S. C.; Reed, S. G.; Davie, J. W.; Avril, M.
10.1101/2023.05.23.541932 — immunology — Posted on 2023-05-23
1182 Conditional control of universal CAR T cells by cleavable OFF-switch adaptors.
Kvorjak, M.; Ruffo, E.; Tivon, Y.; So, V.; parikh, a.; Deiters, A.; Lohmueller, J.
10.1101/2023.05.22.541664 — synthetic biology — Posted on 2023-05-23
1184 A robotic system for automated genetic manipulation and analysis of Caenorhabditis elegans
Li, Z.; Fouad, A. D.; Bowlin, P.; Fan, Y.; He, S.; Chang, M.-C.; Du, A.; Teng, C.; Kassouni, A.; Ji, H.; Raizen, D. M.; Fang-Yen, C.
10.1101/2022.11.18.517134 — bioengineering — Posted on 2023-05-23
1185 Oxamniquine Derivatives Overcome Praziquantel Treatment Limitations for Schistosomiasis
Alwan, S. N.; Taylor, A. B.; Rhodes, J.; Tidwell, M.; McHardy, S. F.; LoVerde, P. T.
10.1101/2023.05.23.541778 — biochemistry — Posted on 2023-05-23
1188 Exploring the Chain Release Mechanism from an Atypical Apicomplexan Polyketide Synthase
Keeler, A. M.; Petruzziello, P. E.; Boger, E. G.; D'Ambrosio, H. K.; Derbyshire, E. R.
10.1101/2023.05.23.541938 — biochemistry — Posted on 2023-05-23
1189 Seasonal Variation in Bacterial Community Structures of Mangrove Sediments
Wang, N.; Liu, L.; Guo, Z.; Xu, S.; Zhang, R.; Zhong, C.; Shi, S.; He, Z.
10.1101/2023.05.23.541861 — ecology — Posted on 2023-05-23
1190 Steamed broccoli sprouts alleviate DSS-induced inflammation and retain gut microbial biogeography in mice.
Holman, J. M.; Colucci, L.; Baudewyns, D.; Balkan, J.; Hunt, T.; Hunt, B.; Kinney, M.; Holcomb, L.; Chen, G.; Moses, P. L.; Mawe, G. M.; Zhang, T.; Li, Y.; Ishaq, S. L.
10.1101/2023.01.27.522641 — microbiology — Posted on 2023-05-23
1193 Disrupted memory T cell expansion in HIV-exposed uninfected infants is preceded by premature skewing of T cell receptor clonality.
Dzanibe, S.; Wilk, A. J.; Canny, S.; Ranganath, T.; Alinde, B.; Rubelt, F.; Huang, H.; Davis, M.; Holmes, S. P.; Jaspan, H. B.; Blish, C. A.; Gray, C. M.
10.1101/2023.05.19.540713 — immunology — Posted on 2023-05-23
1194 Molecular recording of calcium signaling via calcium-dependent protein proximity labeling
Kim, J. W.; Yong, A. J. H.; Aisenberg, E. E.; Dawson, T. M.; Dawson, V. L.; Jan, Y.-N.; Ingolia, N. T.; Wang, W.; Gao, R.; Bateup, H. S.
10.1101/2022.07.14.500122 — neuroscience — Posted on 2023-05-23
1195 Prediction of cancer treatment response from histopathology images through imputed transcriptomics
Hoang, D.-T.; Dinstag, G.; Hermida, L. C.; Ben-Zvi, D. S.; Elis, E.; Caley, K.; Sammut, S.-J.; Sinha, S.; Sinha, N.; Dampier, C. H.; Stossel, C.; Patil, T.; Rajan, A.; Lassoued, W.; Strauss, J.; Bailey, S.; Allen, C.; Redman, J.; Beker, T.; Jiang, P.; Golan, T.; Wilkinson, S.; Sowalsky, A. G.; Pine, S. R.; Caldas, C.; Gulley, J. L.; Aldape, K.; Aharonov, R.; Stone, E. A.; Ruppin, E.
10.1101/2022.06.07.495219 — cancer biology — Posted on 2023-05-23
1197 Retrieved Sequence Augmentation for Protein Representation Learning
Ma, C.; Zhao, H.; Zheng, L.; Xin, J.; Li, Q.; Wu, L.; Deng, Z.; Lu, Y.; Liu, Q.; Kong, L.
10.1101/2023.02.22.529597 — bioinformatics — Posted on 2023-05-23
1198 Early life exposure to cigarette smoke primes lung function changes and DNA methylation changes at Cyp1a1 upon exposure later in life
Onuzulu, C. D.; Lee, S.; Basu, S.; Comte, J.; Hai, Y.; Hizon, N.; Chadha, S.; Fauni, M. S.; Kahnamoui, S.; Xiang, B.; Halayko, A. J.; Dolinsky, V. W.; Pascoe, C. D.; Jones, M. J.
10.1101/2023.03.03.530858 — genetics — Posted on 2023-05-23
1199 The path to "femmes fatales": the evolution of toxin resistance in predatory fireflies.
Yang, L.; Borne, F.; Aardema, M. L.; Zhen, Y.; Peng, J.; Wu, M.; Visconti, R.; Betz, A.; Roland, B. P.; Talsma, A. D.; Palladino, M.; Petschenka, G.; Andolfatto, P.
10.1101/2023.03.08.531760 — evolutionary biology — Posted on 2023-05-23
1211 Recovery of a learned behavior despite partial restoration of neuronal dynamics after chronic inactivation of inhibitory neurons
Torok, Z.; Luebbert, L.; Feldman, J.; Duffy, A.; Nevue, A.; Wongso, S.; Mello, C.; Fairhall, A.; Pachter, L.; Gonzalez, W. G.; Lois, C.
10.1101/2023.05.17.541057 — neuroscience — Posted on 2023-05-23
1212 A transposase-derived gene required for human brain development
Jubierre Zapater, L.; Rodriguez Fos, E.; Planas-Felix, M.; Lewis, S.; Cameron, D.; Demarest, P.; Nabila, A.; Zhao, J.; Bergin, P.; Reed, C.; Yamada, M.; Pagnozzi, A.; Nava, C.; Bourel-Ponchel, E.; Neilson, D. E.; Dursun, A.; Ozgul, R. K.; Tuna Akar, H.; Socci, N.; Hayes, M.; Rabadan, R.; Torrents, D.; Kruer, M. C.; Toth, M.; Kentsis, A.
10.1101/2023.04.28.538770 — neuroscience — Posted on 2023-05-23
1213 Multi-view learning to unravel the different levels underlying hepatitis B vaccine response
Affaticati, F.; Bartholomeus, E.; Mullan, K.; Van Damme, P.; Beutels, P.; Ogunjimi, B.; Laukens, K.; Meysman, P.
10.1101/2023.02.23.529670 — systems biology — Posted on 2023-05-23
1214 A scalable framework for high-throughput identification of functional origins of replication in non-model bacteria
Gilbert, C.; Brumwell, S. L.; Crits-Christoph, A.; Kang, S. C.; Martin-Moldes, Z.; Alsharif, W.; Esmurria, A.; Nguyen, M.-A.; Lee, H. H.; Ostrov, N.
10.1101/2023.05.19.541510 — synthetic biology — Posted on 2023-05-23
1215 Thermoprotection by a cell membrane-localized metacaspase in a green alga
Zou, Y.; Sabljic, I.; Horbach, N.; Dauphinee, A.; Asman, A.; Temino, L. S.; Drag, M.; Stael, S.; Poreba, M.; Stahlberg, J.; Bozhkov, P.
10.1101/2023.04.28.538660 — plant biology — Posted on 2023-05-23
1216 Spatial autocorrelation dimension as a potential determinant for the temporal persistence of human atrial and ventricular fibrillation.
Dharmaprani, D.; Jenkins, E. V.; Tiver, K.; Quah, J. X.; Mitchell, L.; Tung, M.; Ahmad, W.; Stoyanov, N.; Aguilar, M.; Nash, M. P.; Clayton, R. H.; Nattel, S.; Ganesan, A. N.
10.1101/2023.04.12.536515 — physiology — Posted on 2023-05-23
1217 Inference of annealed protein fitness landscapes with AnnealDCA
Sesta, L.; Pagnani, A.; Fernandez-de-Cossio-Diaz, J.; Uguzzoni, G.
10.1101/2023.05.19.541442 — biophysics — Posted on 2023-05-23
1219 Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain
Harris, N. J.; Jenkins, M. L.; Nam, S.-E.; Rathinaswamy, M. K.; Parson, M. A.; Ranga-Prasad, H.; Dalwadi, U.; Moeller, B. E.; Sheeky, E.; Hansen, S. D.; Yip, C. K.; Burke, J. E.
10.1101/2023.04.12.536585 — biochemistry — Posted on 2023-05-23
1222 Evolutionary dynamics of genome size and content during the adaptive radiation of Heliconiini butterflies
Cicconardi, F.; Milanetti, E.; Pinheiro de Castro, E. C.; Mazo-Vargas, A.; Belleghem, S. M.; Ruggieri, A. A.; Rastas, P.; Hanly, J. J.; Evans, E.; Jiggins, C. D.; McMillan, W. O.; Papa, R.; di Marino, D.; Martin, A.; Montgomery, S. H.
10.1101/2022.08.12.503723 — evolutionary biology — Posted on 2023-05-23
1223 Nitrogen niche partitioning between tropical legumes and grasses strengthens under elevated CO2
Churchill, A. C.; Zhang, H.; Kim, G. w.; Catunda, K. L. M.; Anderson, I. C.; Isbell, F. I.; Moore, B.; Pendall, E.; Plett, J. M.; Powell, J.; Power, S. A.
10.1101/2023.01.16.524162 — ecology — Posted on 2023-05-23
1224 Novel determinants of NOTCH1 trafficking and signaling in breast epithelial cells
Kobia, F. M.; Castro e Almeida, L.; Carminati, F.; Andronache, A.; Lavezzari, F.; Wade, M.; Vaccari, T.
10.1101/2023.03.05.531156 — cell biology — Posted on 2023-05-23
1226 Suppression of tumor cell lactate-generating signaling pathways eradicates murine PTEN/p53-deficient aggressive-variant prostate cancer via macrophage phagocytosis
Chaudagar, K. K.; Hieromnimon, H.; Kelley, A.; Labadie, B.; Shafran, J.; Rameshbabu, S.; Drovetsky, C.; Bynoe, K.; Solanki, A.; Markiewicz, E.; Fan, X.; Loda, M.; Patnaik, A.
10.1101/2023.05.23.540590 — cancer biology — Posted on 2023-05-23
1228 BioModelsML: Building a FAIR and reproducible collection of machine learning models in life sciences and medicine for easy reuse
Tiwari, D. D.; Hoffmann, N.; Didi, K.; Deshpande, S.; Ghosh, S.; Nguyen, T. V. N.; Raman, K.; Hermjakob, H.; Malik Sheriff, R. S.
10.1101/2023.05.22.540599 — bioinformatics — Posted on 2023-05-23
1233 Nighthawk: acoustic monitoring of nocturnal bird migration in the Americas
Van Doren, B. M.; Farnsworth, A.; Stone, K.; Osterhaus, D. M.; Drucker, J.; Van Horn, G.
10.1101/2023.05.22.541336 — ecology — Posted on 2023-05-23
1234 Antimicrobial peptide glatiramer acetate targets Pseudomonas aeruginosa lipopolysaccharides to breach membranes without altering lipopolysaccharide modification
Murphy, R. A.; Pizzato, J.; Cuthbertson, L.; Sabnis, A. A.; Edwards, A. M.; Nolan, L. M.; Vorup-Jensen, T.; Larrouy-Maumus, G.; Davies, J. C.
10.1101/2023.05.23.541429 — microbiology — Posted on 2023-05-23
1235 Vaccine-mediated protection against merbecovirus and sarbecovirus challenge in mice
Martinez, D.; Schaefer, A. R.; Gavitt, T.; Mallory, M.; Lee, E.; Catanzaro, N.; Chen, H.; Gully, K.; Scobey, T. D.; Korategere, P.; Brown, A.; Smith, L.; Parks, R.; Barr, M.; Newman, A.; Bowman, C.; Powers, J. M.; Mansouri, K.; Edwards, R. J.; Baric, R. S.; Haynes, B.; Saunders, K. O.
10.1101/2023.05.22.540829 — immunology — Posted on 2023-05-23
1236 Saxitoxin potentiates Zika virus-induced cell death in human neurons but not in neural progenitors and astrocytes
Souza, L. R. Q.; Pedrosa, C. D. S. G.; Pijuan, T. P.; Santos, C. d. S. d.; Vitoria, G. L.; Higa, L.; TANURI, A.; Guimaraes, M. Z.; Rehen, S. K.
10.1101/2023.05.22.541218 — neuroscience — Posted on 2023-05-23
1237 Integrating stereotypes and factual evidence in interpersonal communication
Koch, S. B. J.; Tyborowska, A.; Niermann, H. C. M.; Cillessen, A. H. N.; Roelofs, K.; Basnakova, J.; Stolk, A.
10.1101/2023.05.23.540979 — neuroscience — Posted on 2023-05-23
1240 Distinct accessory roles of Arabidopsis VEL proteins in Polycomb silencing
Franco-Echevarria, E.; Nielsen, M.; Schulten, A.; Cheema, J.; Morgan, T.; Bienz, M.; Dean, C.
10.1101/2023.05.22.541744 — plant biology — Posted on 2023-05-23
1242 Nutritional and genetic variations within foxtail millet (Setaria italica) landraces collected from indigenous communities across the Philippines
EREFUL, N. C.; Reyes, J. A. O.; Cardona, D. E. M.; Alonday, R. C. S.; Mateo, N. O. B.; Jones, H.; Boyd, L.; Delfin, E. F.
10.1101/2023.05.22.541853 — plant biology — Posted on 2023-05-23
1243 SEPALLATA-driven MADS transcription factor tetramerization is required for inner whorl floral organ development
Hugouvieux, V. G.; Blanc-Mathieu, R.; Paul, M.; Janeau, A.; Xu, X.; Lucas, J.; Lai, X.; Galien, A.; Yan, W.; Nanao, M. H.; Kaufmann, K.; Parcy, F.; Zubieta, C.
10.1101/2023.05.23.541941 — plant biology — Posted on 2023-05-23
1244 Soybean-SCN duel: Novel insight into Soybean's Resistant Responses to Heterodera glycines
Torabi, S.; Seifi, S.; Geddes-McAlister, J.; Tenuta, A.; Wally, O.; Torkamaneh, D.; Eskandari, M.
10.1101/2023.05.22.541756 — plant biology — Posted on 2023-05-23
1246 Cynipid wasps systematically reprogram host metabolism and restructure cell walls in developing galls
Markel, K.; Novak, V.; Bowen, B.; Tian, Y.; Chen, Y.-C.; Sirirungruang, S.; Zhou, A.; Louie, K.; Northen, T.; Eudes, A.; Scheller, H.; Shih, P.
10.1101/2023.05.22.540048 — plant biology — Posted on 2023-05-23
1249 Sex- and Age-dependent Skin Mechanics - A Detailed Look in Mice
Lin, C.-Y.; Sugerman, G. P.; Kakaletsis, S.; Meador, W. D.; Tepole, A. B.; Rausch, M. K.
10.1101/2023.03.08.531781 — biophysics — Posted on 2023-05-23
1252 Wildlife exposure to SARS-CoV-2 across a human use gradient
Goldberg, A. R.; Langwig, K. E.; Marano, J. M.; Rai, P.; Sharp, A. K.; Brown, K. L.; Ceci, A.; Kailing, M. J.; Briggs, R.; Roby, C.; Brown, A. M.; Weger-Lucarelli, J.; Finkielstein, C. V.; Hoyt, J. R.
10.1101/2022.11.04.515237 — ecology — Posted on 2023-05-23
1253 Staining and resin embedding of whole Daphnia samples for micro-CT imaging
Ngu, M. S.; Vanselow, D. J.; Zaino, C. R.; Sugarman, A. Q.; Yakovlev, M. A.; Cheng, K. C.; Ang, K. C.
10.1101/2023.05.21.541654 — zoology — Posted on 2023-05-23
1260 A redox switch allows binding of ferrous and ferric ions in the cyanobacterial iron binding protein FutA from Prochlorococcus
Bolton, R.; Machelett, M. M.; Stubbs, J.; Axford, D.; Caramello, N.; Catapano, L.; Maly, M.; Rodrigues, M. J.; Cordery, C.; Tizzard, G. J.; MacMillan, F.; Engilberge, S.; von Stetten, D.; Tosha, T.; Sugimoto, H.; Worrall, J. A.; Webb, J. S.; Zubkov, M.; Coles, S.; Mathieu, E.; Steiner, R. A.; Murshudov, G. N.; Schrader, T. E.; Orville, A. M.; Royant, A.; Evans, G.; Hough, M. A.; Owen, R.; Tews, I.
10.1101/2023.05.23.541926 — biophysics — Posted on 2023-05-23
1262 Chondroitin sulfate, dermatan sulfate, and hyaluronic acid differentially modify the biophysical properties of collagen-based hydrogels
Cortes-Medina, M.; Bushman, A. R.; Beshay, P. E.; Adorno, J. J.; Menyhert, M. M.; Hildebrand, R. M.; Agarwal, S. S.; Avendano, A.; Song, J. W.
10.1101/2023.05.22.541626 — bioengineering — Posted on 2023-05-23
1263 Discovery of the apiosyltransferase, celery UGT94AX1 that catalyzes the biosynthesis of a flavone glycoside, apiin
Yamashita, M.; Fujimori, T.; An, S.; Iguchi, S.; Takenaka, Y.; Kajiura, H.; Yoshizawa, T.; Matsumura, H.; Kobayashi, M.; Ono, E.; Ishimizu, T.
10.1101/2023.05.22.541790 — biochemistry — Posted on 2023-05-23
1265 Pelvic irradiation induces behavioral and neuronal damage through gut dysbiosis in a rat model
Venkidesh, B. S.; Narasimhamurthy, R. K.; Jnana, A.; Reghunathan, D.; Sharan, K.; Chandraguthi, S. G.; Mumbrekar, K. D.
10.1101/2023.05.21.541625 — neuroscience — Posted on 2023-05-23
1267 New vistas for epileptogenic zone (EZ) localization and interpretation
Wang, S. H.; Arnulfo, G.; Nobili, L.; Myrov, V.; Ferrari, P.; Ciuciu, P.; Palva, S.; Palva, J. M.
10.1101/2023.05.21.541570 — physiology — Posted on 2023-05-23
1268 Machine-learning guided Venom Induced Dermonecrosis Analysis tooL: VIDAL
Laprade, W. M.; Bartlett, K. E.; Christensen, C. R.; Kazandjian, T. D.; Patel, R. N.; Crittenden, E.; Dawson, C. A.; Mansourvar, M.; Wolff, D. S.; Fryer, T. J.; Laustsen, A. H.; Casewell, N. R.; Gutierrez, J. M.; Hall, S. R.; Jenkins, T. P.
10.1101/2023.05.21.541619 — pharmacology and toxicology — Posted on 2023-05-23
1272 Rapid cloning-free mutagenesis of new SARS-CoV-2 variants using a novel reverse genetics platform
Kipfer, E. T.; Hauser, D.; Lett, M. J.; Otte, F.; Urda, L.; Zhang, Y.; Lang, C. M. R.; Chami, M.; Mittelholzer, C.; Klimkait, T.
10.1101/2023.05.11.540343 — molecular biology — Posted on 2023-05-23
1275 Unexpected Kif4a functions in adult regeneration encompass a dual role in neurons and in proliferative repair Schwann cells.
Correia, P. D.; de Sousa, B. M.; Astrain, J. C.; de Faria, J. P.; Estrada, V.; Relvas, J. B.; Müller, H. W.; Carriel, V.; Bosse, F.; Vieira, S. I.
10.1101/2023.05.21.541636 — neuroscience — Posted on 2023-05-23
1278 Hydraulic retention time drives changes in energy production and the anodic microbiome of a microbial fuel cell (MFC)
Castellano-Hinojosa, A.; Gallardo-Altamirano, M. J.; Pozo, C.; Gonzalez-Martinez, A.; Gonzalez-Lopez, J.
10.1101/2023.05.21.541624 — bioengineering — Posted on 2023-05-23
1279 Dynamic Expedition of Leading Mutations in SARS-CoV-2 Spike Glycoproteins
Hasan, M.; He, Z.; Jia, M.; Leung, A. C. F.; Natarajan, K.; Xu, W.; Yap, S. Q.; Zhou, F.; Chen, S.; Su, H.; Zhu, K.; Su, H.
10.1101/2021.12.29.474427 — evolutionary biology — Posted on 2023-05-23
1281 Biodiversity responses to forest cover loss: taxonomy and metrics matter
de Araujo Martins, C.; Pays, O.; Souza, F. L.; Renaud, P. C.; Valente Neto, F.; Silveira, M.; Ochoa Quintero, J. M.; Provete, D. B.; Cavalcante Santos, C.; Melo, I.; Rodrigues, M. E.; Duleba, S.; Valle Nunes, A.; Ceballos Rivera, O. d. J.; de Oliveira Roque, F.
10.1101/2023.05.21.541657 — ecology — Posted on 2023-05-23
1282 Epidermal Eg5 promotes X-ROS dependent paclitaxel neurotoxicity
Diaz, A. C.; Cirrincione, A. M.; Schmidt, N. A.; Ugo, M. J.; Sanchez, M. C. A.; Reimonn, C. A.; Wuchty, S.; Pellegrini, A. D.; Rude, L. R.; Pappalardo, L. G.; Regan, D. P.; Howell, C.; Hrstka, S.; Dasari, S.; Lisse, T. S.; Harrison, B. J.; Xu, M. X.; Staff, N. P.; Rieger, S.
10.1101/2023.05.22.541784 — cell biology — Posted on 2023-05-23
1283 Peroxisomal tail-anchored proteins do not reach peroxisomes via ER, instead mitochondria can be involved.
Somborac, T.; Bal, G. L.; Fatima, K.; Vihinen, H.; Paatero, A.; Jokitalo, E.; Paavilainen, V. O.; Konovalova, S.
10.1101/2023.05.22.541719 — cell biology — Posted on 2023-05-23
1284 Breakthrough infections by SARS-CoV-2 variants boost cross-reactive hybrid immune responses in mRNA-vaccinated Golden Syrian Hamsters
Garcia-Bernalt Diego, J.; Singh, G.; Jangra, S.; Handrejk, K.; Laporte, M.; Chang, L. A.; El Zahed, S. S.; Pache, L.; Chang, M. W.; Warang, P.; Aslam, S.; Mena, I.; Webb, B. T.; Benner, C.; Garcia-Sastre, A.; Schotsaert, M.
10.1101/2023.05.22.541294 — microbiology — Posted on 2023-05-23
1285 A framework for ultra-low input spatial tissue proteomics
Makhmut, A.; Qin, D.; Fritzsche, S.; Nimo, J.; Koenig, J.; Coscia, F.
10.1101/2023.05.13.540426 — systems biology — Posted on 2023-05-23
1286 Somatic hypermutation patterns in immunoglobulin variable regions are established independently of the local transcriptional landscape
Schoeberl, U. E.; Fitz, J.; Froussios, K.; Valieris, R.; Makharova, M.; Ourailidis, I.; Bauer, B.; Neumann, T.; Wiedemann, E.-M.; Steininger, M.; Garcia, A. C.; Mastrovito, M.; Mouquet, H.; Silva, I.; Pavri, R.
10.1101/2022.05.21.492925 — immunology — Posted on 2023-05-23
1287 Dnmt3a1 regulates hippocampus-dependent memory via the downstream target Nrp1
Kupke, J.; Klimmt, J.; Mudlaff, F.; Schwab, M.; Sticht, C.; Oliveira, A. M. M.
10.1101/2023.05.22.541739 — neuroscience — Posted on 2023-05-23
1288 Leading Basic Modes of Spontaneous Activity Drive Individual Functional Connectivity Organization in the Resting Human Brain
Chen, X.; Ren, H.; Tang, Z.; Zhou, K.; Zhou, l.; Zuo, Z.; Cui, X.; Chen, X.; Liu, Z.; He, Y.; Liao, X.
10.1101/2023.05.23.541862 — neuroscience — Posted on 2023-05-23
1292 Novel Curcuphenol Analogues Possess Anti-Metastatic Biologic Activity
Ellis, S. L. S.; Nohara, L. L.; Dada, S.; Saranchova, I.; Munro, L.; Choi, K. B.; Garrovillas, E.; Pfeifer, C. G.; Williams, D. E.; Cheng, P.; Andersen, R. J.; Jefferies, W.
10.1101/2023.05.15.540833 — biochemistry — Posted on 2023-05-23
1295 A photoreceptor-based hydrogel with red light-responsive reversible sol-gel transition as transient cellular matrix
Hoerner, M.; Becker, J.; Bohnert, R.; Banos, M.; Jerez-Longres, C.; Muehlhaeuser, V.; Haerrer, D.; Wong, T. W.; Meier, M.; Weber, W.
10.1101/2023.04.04.535523 — synthetic biology — Posted on 2023-05-23
1298 cellsnake: a user-friendly tool for single cell RNA sequencing analysis
Umu, S. U.; Rapp Vander-Elst, K.; Karlsen, V. T.; Chouliara, M.; Baekkevold, E. S.; Jahnsen, F. L.; Domanska, D.
10.1101/2023.05.03.539204 — bioinformatics — Posted on 2023-05-23
1300 Evolutionary dynamics of genome size and content during the adaptive radiation of Heliconiini butterflies
Cicconardi, F.; Milanetti, E.; Pinheiro de Castro, E. C.; Mazo-Vargas, A.; Belleghem, S. M.; Ruggieri, A. A.; Rastas, P.; Hanly, J. J.; Evans, E.; Jiggins, C. D.; McMillan, W. O.; Papa, R.; di Marino, D.; Martin, A.; Montgomery, S. H.
10.1101/2022.08.12.503723 — evolutionary biology — Posted on 2023-05-23
1301 RIPK3 promotes brain region-specific interferon signaling and restriction of tick-borne flavivirus infection
Lindman, M.; Angel, J. P.; Estevez, I.; Chang, N. P.; Chou, T.-W.; McCourt, M.; Atkins, C.; Daniels, B. P.
10.1101/2023.01.23.525284 — immunology — Posted on 2023-05-23
1303 Modeling and Simulation of Neocortical Micro- and Mesocircuitry. Part II: Physiology and Experimentation
Isbister, J. B.; Ecker, A.; Pokorny, C.; Bolanos-Puchet, S.; Egas Santander, D.; Arnaudon, A.; Awile, O.; Barros-Zulaica, N.; Blanco Alonso, J.; Boci, E.; Chindemi, G.; Courcol, J.-D.; Damart, T.; Delemontex, T.; Dietz, A.; Ficarelli, G.; Gevaert, M.; Herttuainen, J.; Ivaska, G.; Ji, W.; Keller, D.; King, J.; Kumbhar, P.; Lapere, S.; Litvak, P.; Mandge, D.; Muller, E. B.; Pereira, F.; Planas, J.; Ranjan, R.; Reva, M.; Romani, A.; Rössert, C.; Schürmann, F.; Sood, V.; Teska, A.; Tuncel, A.; Van Geit, W.; Wolf, M.; Markram, H.; Ramaswamy, S.; Reimann, M. W.
10.1101/2023.05.17.541168 — neuroscience — Posted on 2023-05-23
1305 Diverse task-driven modeling of macaque V4 reveals functional specialization towards semantic tasks
Cadena, S. A.; Willeke, K. F.; Restivo, K.; Denfield, G.; Sinz, F. H.; Bethge, M.; Tolias, A. S.; Ecker, A. S.
10.1101/2022.05.18.492503 — neuroscience — Posted on 2023-05-23
1308 Genetics of skeletal proportions in two different populations
Bartell, E.; Lin, K.; Tsuo, K.; Gan, W.; Vedantam, S.; Cole, J. B.; Baronas, J. M.; Yengo, L.; Marouli, E.; Amariuta, T.; GIANT Consortium, ; Renthal, N. E.; Jacobsen, C. M.; Salem, R.; Walters, R. G.; Hirschhorn, J. N.
10.1101/2023.05.22.541772 — genetics — Posted on 2023-05-23
1309 Using developmental rules to align microevolutionwith macroevolution
Machado, F. A.; Mongle, C. S.; Slater, G.; Penna, A.; Wisniewski, A.; Soffin, A.; Dutra, V.; Uyeda, J. C.
10.1101/2022.08.19.504140 — evolutionary biology — Posted on 2023-05-23
1311 Genomic Analysis of Blomia tropicalis Identifies Novel Allergens for Component-Resolved Diagnosis of Mite Allergy
XIONG, Q.; Liu, X.; Wan, A. T.-Y.; Malainual, N.; Xiao, X.; Tang, M.-F.; Ng, J. K.-W.; Shin, S.-K.; Sio, Y. Y.; WANG, M.; Sun, B.; Leung, T.-F.; Chew, F. T.; Tungtrongchitr, A.; Tsui, S. K.-W.
10.1101/2023.02.09.527948 — immunology — Posted on 2023-05-23
1312 Inflammation durably imprints memory CD4+ T cells
Gray-Gaillard, S. L.; Solis, S.; Chen, H.; Monteiro, C.; Ciabattoni, G.; Samanovic, M. I.; Cornelius, A. R.; Williams, T.; Geesey, E.; Rodriguez, M.; Ortigoza, M. B.; Ivanova, E. N.; Koralov, S. B.; Mulligan, M. J.; Herati, R. S.
10.1101/2022.11.15.516351 — immunology — Posted on 2023-05-23
1314 Identifying cellular markers of focal cortical dysplasia type II with cell-type deconvolution and single-cell signatures
Galvao, I. C.; Kandratavicius, L.; Messias, L. A.; Athie, M. C. P.; Assis-Mendonca, G. R.; Alvim, M. K. M.; Ghizoni, E.; Tedeschi, H.; Yasuda, C. L.; Cendes, F.; Vieira, A. S.; Rogerio, F.; Lopes-Cendes, I.; Veiga, D. F. T.
10.1101/2023.05.22.541770 — neuroscience — Posted on 2023-05-23
1317 Discovery of a carbonic anhydrase-Rubisco complex within the alpha-carboxysome
Blikstad, C.; Dugan, E. J.; Laughlin, T. G.; Turnsek, J. B.; Liu, M. D.; Shoemaker, S. R.; Vogiatzi, N.; Remis, J. P.; Savage, D. F.
10.1101/2021.11.05.467472 — biochemistry — Posted on 2023-05-23
1322 Mitochondrial citrate carrier SLC25A1 is a dosage-dependent regulator of metabolic reprogramming and morphogenesis in the developing heart
Ohanele, C.; Peoples, J. N.; Karlstaedt, A.; Geiger, J. T.; Gayle, A. D.; Ghazal, N.; Sohani, F.; Brown, M. E.; Davis, M. E.; Porter, G. A.; Faundez, V.; Kwong, J. Q.
10.1101/2023.05.22.541833 — developmental biology — Posted on 2023-05-22
1324 Phosphatidylinositol 4-kinase III alpha governs cytoskeletal organization for invasiveness of liver cancer cells
Tran, C. S.; Kersten, J.; Breinig, M.; Yan, J.; Poth, T.; Colasanti, O.; Riedl, T.; Faure-Dupuy, S.; Diehl, S.; Verhoye, L.; Li, T.-F.; Lingemann, M.; Schult, P.; Ahlen, G.; Frelin, L.; Kuehnel, F.; Breuhahn, K.; Vondran, F. W. R.; Meuleman, P.; Heikenwaelder, M.; Schirmacher, P.; Saellberg, M.; Bartenschlager, R.; Laketa, V.; Tschaharganeh, D. F.; Lohmann, V.
10.1101/2023.05.22.541742 — cell biology — Posted on 2023-05-22
1325 Cbl and Cbl-b Ubiquitin Ligases are Essential for Intestinal Epithelial Stem Cell Maintenance
Zutshi, N.; Mohapatra, B. C.; Mondal, P.; An, W.; Goetz, B. T.; Wang, S.; Li, S.; Storck, M. D.; Mercer, D.; Black, A. R.; Thayer, S. P.; Black, J.; Lin, C.; Band, V.; Band, H.
10.1101/2023.05.17.541154 — cell biology — Posted on 2023-05-23
1326 Targeted insertion and reporter transgene activity at a gene safe harbor of the human blood fluke, Schistosoma mansoni
Tanno, W. I.; Moescheid, M. F.; Chaparro, C.; Mann, V. H.; Quack, T.; Rodpai, R.; Miller, A. N.; Wistiphongpun, P.; Buakaew, W.; Mentink-Kane, M.; Miller, L.; Schmid, S.; Popratiloff, A.; Grevelding, C.; Grunau, C.; Brindley, P. J.
10.1101/2022.09.02.506379 — molecular biology — Posted on 2023-05-22
1328 Non-canonical D1-D2 recombination produces two types of rearrangements and represents a conservative hidden stage of T-cell receptor beta chain generation
Smirnova, A. O.; Miroshnichenkova, A. M.; Belyaeva, L. D.; Kelmanson, I. V.; Lebedev, Y. B.; Mamedov, I. Z.; Chudakov, D. M.; Komkov, A. Y.
10.1101/2023.04.21.537904 — immunology — Posted on 2023-05-23
1335 Gene-level alignment of single cell trajectories informs the progression of in vitro T cell differentiation
Sumanaweera, D.; Suo, C.; Cujba, A.-M.; Muraro, D.; Dann, E.; Polanski, K.; Steemers, A. S.; Lee, W.; Oliver, A. J.; Park, J.-E.; Meyer, K. B.; Dumitrascu, B.; Teichmann, S. A.
10.1101/2023.03.08.531713 — bioinformatics — Posted on 2023-05-22
1337 Phytocystatin 6 is a context-dependent, tight-binding inhibitor of Arabidopsis thaliana legumain isoform β
Santos, N. P.; Soh, W. T.; Demir, F.; Tenhaken, R.; Briza, P.; Huesgen, P. F.; Brandstetter, H.; Dall, E.
10.1101/2023.05.22.541692 — biochemistry — Posted on 2023-05-22
1338 Stability Oracle: A Structure-Based Graph-Transformer for Identifying Stabilizing Mutations
Diaz, D. J.; Gong, C.; Ouyang-Zhang, J.; Loy, J. M.; Wells, J. T.; Yang, D.; Ellington, A. J.; Dimakis, A.; Klivans, A. R.
10.1101/2023.05.15.540857 — biochemistry — Posted on 2023-05-22
1339 Cross-species transcriptomic analysis identifies mitochondrial dysregulation as a functional consequence of the schizophrenia-associated 3q29 deletion
Purcell, R. H.; Sefik, E.; Werner, E.; King, A. T.; Mosley, T. J.; Merritt-Garza, M. E.; Chopra, P.; McEachin, Z. T.; Karne, S.; Raj, N.; Vaglio, B. J.; Sullivan, D.; Firestein, B. L.; Tilahun, K.; Robinette, M. I.; Warren, S. T.; Wen, Z.; Faundez, V.; Sloan, S. A.; Bassell, G. J.; Mulle, J. G.
10.1101/2023.01.27.525748 — genomics — Posted on 2023-05-22
1340 Ecological genomics in the Northern krill uncovers loci for local adaptation across ocean basins
Unneberg, P.; Larsson, M.; Olsson, A.; Wallerman, O.; Petri, A.; Bunikis, I.; Vinnere Pettersson, O.; Papetti, C.; Gislason, A.; Glenner, H.; Cartes, J. E.; Blanco-Bercial, L.; Eriksen, E.; Meyer, B.; Wallberg, A.
10.1101/2023.04.15.537050 — evolutionary biology — Posted on 2023-05-22
1341 Gene Novelties in Amphioxus Illuminate the Early Evolution of Deuterostomes
Xiong, Q.; Yang, K. Y.; Zeng, X.; Wang, M.; Ng, P. K.-S.; Zhou, J.-W.; Ng, J. K.-W.; Law, C. T.-Y.; Du, Q.; Xu, K.; Falkenberg, L. J.; Mao, B.; Chen, J.-Y.; Tsui, S. K.-W.
10.1101/2022.05.18.492404 — evolutionary biology — Posted on 2023-05-22
1344 Endodermal BRD4 mediates epithelial-mesenchymal crosstalk during lung development
Liberti, D.; Wen, H.; Quansah, K. K.; Chandrasekaran, P.; Pankin, J.; Michki, N. S.; Jin, A.; Lu, M.; Neiuwburgh, M. P. D.; Young, L. R.; Jain, R.; Frank, D. B.
10.1101/2023.05.21.541621 — developmental biology — Posted on 2023-05-22
1345 p90RSK2, a new MLCK, rescues contractility in myosin light chain kinase null smooth muscle
Kalra, J. K.; Artamonov, M.; Wang, H.; Franke, A.; Markowska, Z.; Li, J.; Derewenda, Z. S.; Ayon, R. J.; Somlyo, A. V.
10.1101/2023.05.22.541840 — cell biology — Posted on 2023-05-22
1346 Single Cell RNA Sequencing Reveals Emergent Notochord-Derived Cell Subpopulations in the Postnatal Nucleus Pulposus
Zhang, C.; Zhong, L.; Lau, Y. K.; Wu, M.; Yao, L.; Schaer, T. P.; Mauck, R. L.; Malhotra, N. R.; Qin, L.; Smith, L. J.
10.1101/2023.05.21.541589 — cell biology — Posted on 2023-05-22
1348 Stem cells tightly regulate dead cell clearance to maintain tissue fitness
Stewart, K. S.; Gonzales, K. A.; Yuan, S.; Tierney, M. T.; Bonny, A. R.; Yang, Y.; Infarinato, N. R.; Cowley, C. J.; Levorse, J. M.; Pasolli, H. A.; Ghosh, S.; Rothlin, C. V.; Fuchs, E.
10.1101/2023.05.22.541773 — cell biology — Posted on 2023-05-22
1350 p90RSK2, a new MLCK, rescues contractility in myosin light chain kinase null smooth muscle
Kalra, J. K.; Artamonov, M.; Wang, H.; Franke, A.; Markowska, Z.; Li, J.; Derewenda, Z. S.; Ayon, R. J.; Somlyo, A. V.
10.1101/2023.05.22.541840 — cell biology — Posted on 2023-05-22
1351 Anopheles salivary apyrase regulates blood meal hemostasis and drives malaria parasite transmission
Pala, Z. R.; Alves e Silva, T. L.; Minai, M.; Crews, B.; Patino-Martinez, E.; Carmona-Rivera, C.; Valenzuela-Leon, P. C.; Martin-Martin, I.; Flores-Garcia, Y.; Cachau, R. E.; Srivastava, N.; Moore, I. N.; Alves, D. A.; Kaplan, M. J.; Fischer, E.; Calvo, E.; Vega-Rodriguez, J.
10.1101/2023.05.22.541827 — microbiology — Posted on 2023-05-22
1352 Convergent mutations in phage virion assembly proteins enable evasion of Type I CBASS immunity
Richmond-Buccola, D.; Hobbs, S. J.; Garcia, J. M.; Toyoda, H.; Gao, J.; Shao, S.; Lee, A. S.; Kranzusch, P. J.
10.1101/2023.05.21.541620 — microbiology — Posted on 2023-05-22
1353 Conserved features of eye movement related eardrum oscillations (EMREOs) across humans and monkeys
Lovich, S. N.; King, C. D.; Murphy, D. L. K.; Abbasi, H.; Bruns, P.; Shera, C. A.; Groh, J. M.
10.1101/2023.03.08.531768 — neuroscience — Posted on 2023-05-22
1357 Large-scale genomic rearrangements boost SCRaMbLE in Saccharomyces cerevisiae
Li, T.; Zhao, S.; Cheng, L.; Hou, S.; Luo, Z.; Xu, J.; Yu, W.; Jiang, S.; Monti, M.; Schindler, D.; Zhang, W.; Hou, C.; Ma, Y.; Cai, Y.; Boeke, J. D.; Dai, J.
10.1101/2023.05.21.541650 — synthetic biology — Posted on 2023-05-22
1358 Rapid local and systemic jasmonate signalling drives initiation and establishment of plant systemic immunity
Gaikwad, T.; Breen, S.; Breeze, E.; Hussain, R. M. F.; Kulasekaran, S.; de Torres-Zabala, M.; Horsell, D.; Frigerio, L.; Grant, M.
10.1101/2023.05.22.541689 — plant biology — Posted on 2023-05-22
1360 Vimentin filaments integrate low complexity domains in a highly complex helical structure
Eibauer, M.; Weber, M. S.; Kronenberg-Tenga, R.; Beales, C. T.; Boujemaa-Paterski, R.; Turgay, Y.; Sivagurunathan, S.; Kraxner, J.; Koester, S.; Goldman, R. D.; Medalia, O.
10.1101/2023.05.22.541714 — biochemistry — Posted on 2023-05-22
1361 Structural Basis for the Phase Separation of the Chromosome Passenger Complex
Bryan, N. W.; Niedzialkowska, E.; Mayne, L.; Stukenberg, P. T.; Black, B. E.
10.1101/2023.05.22.541822 — biochemistry — Posted on 2023-05-22
1362 Structure of the connexin-43 gap junction channel in a putative closed state
Qi, C.; Acosta-Gutierrez, S.; Lavriha, P.; Othman, A.; Lopez-Pigozzi, D.; Bayraktar, E.; Schuster, D.; Picotti, P.; Zamboni, N.; Bortolozzi, M.; Gervasio, F. L.; Korkhov, V. M.
10.1101/2022.03.26.485947 — biochemistry — Posted on 2023-05-22
1363 Genetic bases of resistance to the rice hoja blanca disease deciphered by a QTL approach
Silva, A.; Montoya, M. E.; Quintero, C.; Cuasquer, J.; Tohme, J.; Graterol, E.; Cruz, M.; Lorieux, M.
10.1101/2022.11.07.515427 — genetics — Posted on 2023-05-22
1366 Lineage-specific genes are clustered with allorecognition loci and respond to GxE factors regulating the switch from asexual to sexual reproduction in Neurospora
Wang, Z.; Wang, Y.; Kasuga, T.; Wang, Y.-W.; Lopez-Giraldez, F.; Zhang, Y.; Zhang, Z.; Dong, C.; Sil, A.; Trail, F.; Yarden, O.; Townsend, J. P.
10.1101/2022.06.10.495464 — evolutionary biology — Posted on 2023-05-22
1368 Rescue of proteotoxic stress and neurodegeneration by the Zn2+ transporter ZIP7
GUO, X.; Mutch, M.; Torres, A. Y.; Nano, M.; McDonald, D.; Chen, Z.; Montell, C.; Dai, W.; Montell, D.
10.1101/2023.05.22.541645 — cell biology — Posted on 2023-05-22
1373 Abrupt permafrost thaw triggers microbial bloom and grazer succession
Scheel, M.; Zervas, A.; Rijkers, R.; Tveit, A. T.; Ekelund, F.; Jimenez, F. C.; Jacobsen, C. S.; Christensen, T. R.
10.1101/2022.08.09.499897 — microbiology — Posted on 2023-05-22
1375 BOLD response is more than just magnitude: improving detection sensitivity through capturing hemodynamic profiles
Chen, G.; Taylor, P. A.; Reynolds, R. C.; Leibenluft, E.; Pine, D. S.; Brotman, M. A.; Pagliaccio, D.; Haller, S. P.
10.1101/2023.02.13.528362 — neuroscience — Posted on 2023-05-22
1376 Bioenergetic-Related Gene Expression in the Hippocampus Predicts Internalizing vs. Externalizing Behavior in a F2 Cross of Selectively-Bred Rats
Hebda-Bauer, E. K.; Hagenauer, M. H.; Blandino, P.; Meng, F.; Chitre, A. S.; Ozel, A. B.; Arakawa, K.; Flagel, S. B.; Watson, S. J.; Palmer, A. A.; Li, J.; Akil, H.
10.1101/2022.07.14.500129 — neuroscience — Posted on 2023-05-22
1378 Reducing the mitochondrial oxidative burden alleviates lipid-induced muscle insulin resistance in humans
Fiorenza, M.; Onslev, J.; Henriquez-Olguin, C.; Persson, K. W.; Hesselager, S. A.; Jensen, T. E.; Wojtaszewski, J. F. P.; Hostrup, M.; Bangsbo, J.
10.1101/2023.04.10.535538 — physiology — Posted on 2023-05-22
1379 Bacterial deamidases modulate ubiquitin structure and dynamics to dysregulate ubiquitin signaling
Agrata, R.; Mohanty, P.; Ravichandran, A.; Kumari, S.; Varshney, N.; GS, A.; Chauhan, K.; Li, J.; Chakrabarti, K.; Byrd, R. A.; Das, R.
10.1101/2023.05.22.541748 — biochemistry — Posted on 2023-05-22
1381 Metabolite Profiling and Phytochemical Investigation of Cytoconstituents of Seneciobiafrae Oliv. & Hiern (Compositae)
Oriyomi, O. V.; ORIYOMI, O. V.; ADEKOLA, M. B.; OGUNDELE, S. B.; AGBEDAHUNSI, M. J.; BABALOLA, O. O.
10.1101/2023.05.21.541662 — biochemistry — Posted on 2023-05-22
1382 Changes in Active Site Loop Conformation Relate to the Transition toward a Novel Enzymatic Activity
Jacquet, P.; Billot, R.; Shimon, A.; Hoekstra, N.; Bergonzi, C.; Jenks, A.; Chabriere, E.; Daude, D.; Elias, M.
10.1101/2023.05.22.541809 — biochemistry — Posted on 2023-05-22
1383 SLC12A9 is a lysosome-detoxifying ammonium - chloride co-transporter
Levin-Konigsberg, R.; Mitra, K.; Nigam, A.; Spees, K.; Hivare, P.; Liu, K.; Kundaje, A.; Krishnan, Y.; Bassik, M.
10.1101/2023.05.22.541801 — cell biology — Posted on 2023-05-22
1385 Extracellular G-quadruplex and Z-DNA protect biofilms from DNase I and forms a DNAzyme with peroxidase activity
Minero, G. A. S.; Moellebjerg, A.; Thiesen, C.; Johansen, M. I.; Joergensen, N. P.; Birkedal, V.; Otzen, D.; Meyer, R. L.
10.1101/2023.05.22.541711 — microbiology — Posted on 2023-05-22
1386 Dynamic enhancer interactome promotes senescence and aging
Wang, L.; Donahue, G.; Zhang, C.; Havas, A.; Lei, X.; Xu, C.; Wang, W.; Vahedi, G.; Adams, P. D.; Berger, S. L.
10.1101/2023.05.22.541769 — molecular biology — Posted on 2023-05-22
1387 Discovery of new deaminase functions by structure-based protein clustering
Huang, J.; Lin, Q.; Fei, H.; He, Z.; Xu, H.; Li, Y.; Qu, K.; Han, P.; Gao, Q.; Li, B.; Liu, G.; Zhang, L.; Hu, J.; Zhang, R.; Zuo, E.; Luo, Y.; Ran, Y.; Qiu, J.-L.; Zhao, K. T.; Gao, C.
10.1101/2023.05.21.541555 — molecular biology — Posted on 2023-05-22
1388 N4-acetylcytidine (ac4C) promotes mRNA localization to stress granules
Kudrin, P.; Singh, A.; Meierhofer, D.; Kusnierczyk, A.; Vang Orom, U. A.
10.1101/2023.05.22.541693 — molecular biology — Posted on 2023-05-22
1389 Development of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic strategy for Alzheimer's disease.
Du, Y.; Bradshaw, W. J.; Leisner, T. M.; Annor-Gyamfi, J. K.; Qian, K.; Bashore, F. M.; Sikdar, A.; Nwogbo, F. O.; Ivanov, A. A.; Frye, S. V.; Gileadi, O.; Brennan, P. E.; Levey, A. I.; the Emory-Sage-SGC TREAT-AD Center, ; Axtman, A. D.; Pearce, K. H.; Fu, H.; Katis, V. L.
10.1101/2023.05.22.541727 — molecular biology — Posted on 2023-05-22
1392 Identification of an anti-CRISPR protein that inhibits the CRISPR-Cas type I-B system in Clostridioides difficile
Muzyukina, P.; Shkaruta, A.; Guzman, N. M.; Andreani, J.; Borges, A. L.; Bondy-Denomy, J.; Maikova, A.; Semenova, E.; Severinov, K.; SOUTOURINA, O.
10.1101/2023.05.22.541795 — microbiology — Posted on 2023-05-22
1394 High prevalence of Bovine Tuberculosis reported in Cattle and Buffalo of Eastern Nepal
Upadhyaya, N.; Shrestha, N.; Dahal, R.; Yadav, S. K.; Thakur, R.; Aryal, D.; Pokharel, S.; Luitel, B.; Rajbhandari, R.; Balseiro, A. M.; de la Fuente, J.; Gortazar, C.; Karmacharya, D.
10.1101/2023.05.21.541660 — microbiology — Posted on 2023-05-22
1400 Massive invasion of organellar DNA drives nuclear genome evolution in Toxoplasma
Namasivayam, S.; Sun, C.; Bah, A. B.; Oberstaller, J.; Pierre-Louis, E.; Etheridge, R. D.; Feschotte, C.; Pritham, E. J.; Kissinger, J. C.
10.1101/2023.05.22.539837 — evolutionary biology — Posted on 2023-05-22
1401 Small extracellular vesicles but not microvesicles from Opisthorchis viverrini promote cell proliferation in human cholangiocytes.
Chaiyadet, S.; Sotillo, J.; Smout, M.; Cooper, M.; Doolan, D.; Waardenberg, A.; Eichenberger, R.; Field, M. A.; Laha, T.; Loukas, A.
10.1101/2023.05.22.540805 — microbiology — Posted on 2023-05-22
1402 Breakthrough infections by SARS-CoV-2 variants boost cross-reactive hybrid immune responses in mRNA-vaccinated Golden Syrian Hamsters
Garcia-Bernalt Diego, J.; Singh, G.; Jangra, S.; Handrejk, K.; Laporte, M.; Chang, L. A.; El Zahed, S. S.; Pache, L.; Chang, M. W.; Warang, P.; Aslam, S.; Mena, I.; Webb, B. T.; Benner, C.; Garcia-Sastre, A.; Schotsaert, M.
10.1101/2023.05.22.541294 — microbiology — Posted on 2023-05-22
1404 Focusing perceptual attention in the past constrains outcome-based learning in the future by adjusting cortico-cortical interactions
Vasilev, D.; Safaee, N.; Iwai, R.; Bahmani, H.; Zouridis, I. S.; Watanabe, M.; Logothetis, N. K.; Totah, N. K.
10.1101/2022.01.22.477334 — neuroscience — Posted on 2023-05-22
1411 Locus coeruleus activity fluctuations set a non-reducible timeframe for mammalian NREM-REM sleep cycles
Osorio-Forero, A.; Foustoukos, G.; Cardis, R.; Cherrad, N.; Devenoges, C.; Fernandez, L. M.; Luthi, A.
10.1101/2023.05.20.541586 — neuroscience — Posted on 2023-05-22
1415 Loss of E3 ligase HvST1 function substantially increases recombination
Orr, J. N.; Mittmann, S. U.; Ramsay, L.; Lewandowska, D.; Barakate, A.; Macaulay, M.; McCallum, N.; Waugh, R.; Colas, I.
10.1101/2023.05.19.541444 — plant biology — Posted on 2023-05-22
1416 Naked mole rats have distinctive cardiometabolic and genetic adaptations to their underground low-oxygen lifestyles
Faulkes, C. G.; Eykyn, T. R.; Miljkovic, J. L.; Charles, R. L.; Prag, H. A.; Patel, N.; Hart, D.; Murphy, M. P.; Bennett, N. C.; Aksentijevic, D.
10.1101/2023.05.19.541451 — physiology — Posted on 2023-05-22
1417 Ablation of Sam50 is associated with fragmentation and alterations in metabolism in human myotubes
Vue, Z.; Vang, C.; Neikirk, K.; Garza-Lopez, E.; Shao, J.-q.; Mungai, M.; Vang, L.; Beasley, H. K.; Marshall, A. G.; Crabtree, A.; Stephens, D. C.; McReynolds, M.; Murray, S. A.; Katti, P.; Gaddy, J. A.; Damo, S. M.; Hinton, A.
10.1101/2023.05.20.541602 — physiology — Posted on 2023-05-22
1418 FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis
Wu, J.; Subbaiah, K. C. V.; Hedaya, O.; Chen, S.; Munger, J.; Tang, W. H. W.; Yan, C.; Yao, P.
10.1101/2023.05.20.541585 — pathology — Posted on 2023-05-22
1419 The spatially resolved tumor microenvironment predicts treatment outcome in relapsed/refractory Hodgkin lymphoma
Aoki, T.; Jiang, A.; Xu, A.; Yin, Y.; Gamboa, A.; Milne, K.; Takata, K.; Miyata-Takata, T.; Wu, S.; Warren, M.; Strong, C.; Goodyear, T.; Morris, K.; Chong, L. C.; Hav, M.; Colombo, A. R.; Telenius, A.; Merrill, B.; Ben-Neriah, S.; Power, M.; Gerrie, A. S.; Weng, A. P.; Karsan, A.; Roth, A.; Farinha, P.; Scott, D. W.; Savage, K. J.; Nelson, B. H.; Merchant, A.; Steidl, C.
10.1101/2023.05.19.541331 — cancer biology — Posted on 2023-05-22
1420 Calorie Restriction Outperforms Bariatric Surgery in a Murine Model of Obesity and Triple-Negative Breast Cancer
Coleman, M. F.; Camp, K. K.; McFarlane, T. L.; Doerstling, S. S.; Khatib, S. A.; Rezeli, E. T.; Lewis, A. G.; Pfeil, A. J.; Smith, L. A.; Fouladi, F.; Gong, W.; Glenny, E. M.; Parker, J. S.; Milne, G. L.; Carroll, I. M.; Fodor, A. A.; Seeley, R.; Hursting, S. D.
10.1101/2023.05.19.541484 — cancer biology — Posted on 2023-05-22
1421 Kaempferide induces apoptosis in cervical cancer by attenuating the HPV oncoproteins, E6 and E7
Nath, L. R.; Alex, V. V.; Aiswarya, S. U.; Rayginia, T. P.; Haritha, N. H.; Keerthana, C. K.; Thulasidasan, A. K. T.; Swetha, M.; Lankalapalli, R. S.; Anto, R. J.
10.1101/2023.05.19.541414 — cancer biology — Posted on 2023-05-22
1428 Telomere-to-telomere genome of the model plant Physcomitrium patens
Bi, G.; Zhao, S.; Yao, J.; Wang, H.; Zhao, M.; Sun, Y.; Hou, X.; Jiao, Y.; Ma, Y.; Yan, J.; Dai, J.
10.1101/2023.05.19.541548 — genomics — Posted on 2023-05-22
1429 Unsupervised Machine Learning Identifies Chromatin Accessibility Regulatory Networks that Define Cell State Transitions in Pluripotency
Arthur, T. D.; Nguyen, J. P.; D'Antonio-Chronowska, A.; Matsui, H.; Silva, N.; Joshua, I. N.; iPSCORE Consortium, ; Young Greenwald, W. W.; D'Antonio, M.; Pera, M. F.; Frazer, K. A.
10.1101/2023.05.20.541447 — genomics — Posted on 2023-05-22
1431 Fibroblasts as an in vitro model of circadian genetic and genomic studies
Francia, M.; Bot, M.; Boltz, T.; De La Hoz, J. F.; Boks, M.; Kahn, R.; Ophoff, R.
10.1101/2023.05.19.541494 — genomics — Posted on 2023-05-22
1433 HYPERURICAEMIA DOES NOT INTERFERE WITH AORTOPATHY IN A MURINE MODEL OF MARFAN SYNDROME
Rodriguez-Rovira, I.; Lopez-Sainz, A.; Palomo-Buitrago, M. E.; Perez, B.; Jimenez-Altayo, F.; Campuzano, V.; Egea, G.
10.1101/2023.05.21.541606 — genetics — Posted on 2023-05-22
1435 Age- and caste-independent piRNAs in the germline and miRNA profiles linked to caste and fecundity in the ant Temnothorax rugatulus
Seistrup, A.-S.; Choppin, M.; Govind, S.; Feldmeyer, B.; Kever, M.; Karaulanov, E.; Seguret, A.; Karunanithi, S.; Ketting, R. F.; Foitzik, S.
10.1101/2023.05.21.541611 — ecology — Posted on 2023-05-22
1438 Genome-wide neighbor effects predict genotype pairs that reduce herbivory in mixed planting
Sato, Y.; Shimizu-Inatsugi, R.; Takeda, K.; Schmid, B.; Nagano, A. J.; Shimizu, K. K.
10.1101/2023.05.19.541411 — ecology — Posted on 2023-05-22
1439 Accelerated Nitrogen Cycling on Seagrass Leaves in a High-CO2 World
Berlinghof, J.; Montilla, L. M.; Peiffer, F.; Quero, G. M.; Marzocchi, U.; Meador, T. B.; Margiotta, F.; Abagnale, M.; Wild, C.; Cardini, U.
10.1101/2023.05.19.541481 — ecology — Posted on 2023-05-22
1440 Tailoring evidence into action: using a codesign approach for biodiversity information in the Tropical Andes
Valdez, J. W.; Pereira, H. M.; Morejon, G. F.; Acosta-Munoz, C.; Bonet Garcia, F. J.; Castro Vergara, L.; Claros, X. R.; Gill, M. J.; Josse, C.; Lafuente-Cartagena, I.; Langstroth, R.; Sheppard, S. N.; Orihuela, G.; Prieto-Albuja, F. J.; Quillahuaman, N.; Teran, M. F.; Zambrana-Torrelio, C. M.; Navarro, L. M.; Fernandez, M.
10.1101/2023.05.20.541564 — ecology — Posted on 2023-05-22
1441 Brain Connectivity Correlates of Breathing and Cardiac Irregularities in SUDEP: A Resting-State fMRI Study
Kassinopoulos, M.; Rolandi, N.; Alphan, L.; Harper, R. M.; Oliveira, J.; Scott, C.; Kozak, L. R.; Guye, M.; Lemieux, L.; Diehl, B.
10.1101/2023.05.19.541412 — neuroscience — Posted on 2023-05-22
1447 The Secondary Somatosensory Cortex Gates Mechanical and Thermal Sensitivity
Taub, D. G.; Jiang, Q.; Pietrafesa, F.; Su, J.; Greene, C.; Blanchard, M. R.; Jain, A.; El-Rifai, M.; Callen, A.; Yager, K.; Chung, C.; He, Z.; Chen, C.; Woolf, C. J.
10.1101/2023.05.19.541449 — neuroscience — Posted on 2023-05-22
1448 Kv7 Channel Opener Retigabine Reduces Self-Administration of Cocaine but Not Sucrose in Rats
Urena, E. S.; Diezel, C. C.; Serna, M.; Halaufia, G.; Majuta, L.; Barber, K. R.; Vanderah, T. W.; Riegel, A. C.
10.1101/2023.05.18.541208 — neuroscience — Posted on 2023-05-22
1451 Exercise modulates human hippocampal-cortical ripple dynamics
Cardenas, A. R.; Ramirez-Villegas, J. F.; Kovach, C. K.; Gander, P. E.; Cole, R. C.; Grossbach, A. J.; Kawasaki, H.; Greenlee, J. D.; Howard, M. A.; Nourski, K. V.; Banks, M. I.; Voss, M. W.
10.1101/2023.05.19.541461 — neuroscience — Posted on 2023-05-22
1452 Human co-ripples facilitate neuronal interactions between cortical locations.
Verzhbinsky, I. A.; Rubin, D. B.; Kajfez, S.; Bu, Y.; Hochberg, L. R.; Cash, S. S.; Halgren, E.
10.1101/2023.05.20.541588 — neuroscience — Posted on 2023-05-22
1454 Foveated metamers of the early visual system
Broderick, W. F.; Rufo, G.; Winawer, J.; Simoncelli, E.
10.1101/2023.05.18.541306 — neuroscience — Posted on 2023-05-22
1456 Do cortical co-ripples bind lines, letters, words, meanings, strategy and action in reading?
Garrett, J. C.; Verzhbinsky, I. A.; Kaestner, E.; Carlson, C.; Doyle, W. K.; Devinsky, O.; Thesen, T.; Halgren, E.
10.1101/2023.05.20.541597 — neuroscience — Posted on 2023-05-22
1461 Novel mechanism of MYC deregulation in Multiple Myeloma
Rahmat, M.; Clement, K.; Alberge, J.-B.; Sklavenitis-Pistofidis, R.; Kodgule, R.; Fulco, C.; Heilpern-Mallory, D.; Nilsson, K.; Dorfman, D.; Engreitz, J.; Getz, G.; Pinello, L.; Ryan, R.; Ghobrial, I. M.
10.1101/2023.05.19.541506 — cancer biology — Posted on 2023-05-22
1462 IL-1β promotes MPN disease initiation by favoring early clonal expansion of JAK2-mutant hematopoietic stem cells
Rai, S.; Zhang, Y.; Grockowiak, E.; Kimmerlin, Q.; Hansen, N.; Stoll, C. B.; Usart, M.; Hao-Shen, H.; Bader, M. S.; Passweg, J.; Dirnhofer, S.; Farady, C. J.; Schroeder, T.; Mendez-Ferrer, S.; Skoda, R. C.
10.1101/2023.05.21.541610 — cancer biology — Posted on 2023-05-22
1465 A chromatinized origin reduces ORC mobility and spatially constrains MCM
Sanchez, H.; Liu, Z.; van Veen, E.; van Laar, T.; Solano, B.; Diffley, J. F. X.; Dekker, N. H.
10.1101/2023.05.18.541303 — biophysics — Posted on 2023-05-22
1467 Reciprocal polarization imaging of complex media.
Xie, Z.; Huang, G.; Lin, W.; Jin, X.; Qian, X.; Xu, M.
10.1101/2023.05.19.541234 — biophysics — Posted on 2023-05-22
1469 Inference of annealed protein fitness landscapes with AnnealDCA
Uguzzoni, G.; Sesta, L.; Pagnani, A.; Fernandez-de-Cossio-Diaz, J.
10.1101/2023.05.19.541442 — biophysics — Posted on 2023-05-22
1470 scTIE: data integration and inference of gene regulation using single-cell temporal multimodal data
Lin, Y.; Wu, T.-Y.; Chen, X.; Wan, S.; Chao, B.; Xin, J.; Yang, J. Y. H.; Wong, W. H.; Wang, Y. X. R.
10.1101/2023.05.18.541381 — bioinformatics — Posted on 2023-05-22
1472 WebAtlas pipeline for integrated single cell and spatial transcriptomic data
Li, T.; Horsfall, D.; Basurto-Lozada, D.; Roberts, K.; Prete, M.; Lawrence, J. E. G.; He, P.; Tuck, E.; Moore, J.; Ghazanfar, S.; Teichmann, S.; Haniffa, M.; Bayraktar, O. A.
10.1101/2023.05.19.541329 — bioinformatics — Posted on 2023-05-22
1477 MyeloDB: A multi-omics resource for Multiple Myeloma
Kumar, A.; Kumar, K. V.; Kundal, K.; Sengupta, A.; R, K.; Kumar, R.
10.1101/2023.05.18.541396 — genomics — Posted on 2023-05-22
1479 Expression, not sequence, distinguishes miR-238 from its miR-239ab sister miRNAs in promoting longevity in Caenorhabditis elegans
Chipman, L. B.; Luc, S.; Nicastro, I. A.; Hulahan, J. J.; Dann, D. C.; Bodas, D. M.; Pasquinelli, A. E.
10.1101/2023.05.18.541360 — genetics — Posted on 2023-05-22
1482 Listening to tropical forest soils
Metcalf, O. C.; Baccaro, F.; Barlow, J.; Berenguer, E.; Bradfer-Lawrence, T.; Chessini Rossi, L.; Marinho do Vale, E.; Lees, A. C.
10.1101/2023.05.19.541323 — ecology — Posted on 2023-05-22
1485 Ampk activation by glycogen expenditure primes the exit of naive pluripotency
Kim, S.-M.; Kwon, E.-J.; Oh, J.-Y.; Kim, H. S.; Park, S.; Jang, G.; Do, J. T.; Kim, K.-T.; Cha, H.-J.
10.1101/2023.05.19.541467 — developmental biology — Posted on 2023-05-22
1487 Single cell transcriptomics reveals cell type specific features of developmentally regulated responses to lipopolysaccharide between birth and 5 years.
Read, J. F.; Serralha, M.; Armitage, J.; Iqbal, M. M.; Cruickshank, M. N.; Saxena, A.; Strickland, D. H.; Waithman, J.; Holt, P. G.; Bosco, A.
10.1101/2023.05.18.541356 — immunology — Posted on 2023-05-22
1488 Neurophysiological trajectories in Alzheimer's disease progression
Kudo, K.; Ranasinghe, K. G.; Morise, H.; Syed, F.; Sekihara, K.; Rankin, K. P.; Miller, B. L.; Kramer, J.; Rabinovici, G.; Vossel, K.; Kirsch, H. E.; Nagarajan, S.
10.1101/2023.05.18.541379 — neuroscience — Posted on 2023-05-22
1489 Characterization of predictive power of extracellular signal recordings in a cerebral ischemia animal model
Matinyan, S.; Hovhannisyan, L.; Hakobyan, A.; Khamperyan, A.; Hayrapetyan, L.; Yenkoyan, K.
10.1101/2023.05.19.541417 — neuroscience — Posted on 2023-05-22
1493 Proton motive force dissipation drives flavodiiron proteins to the thylakoid membrane for ferredoxin-powered O2 photoreduction
Nikkanen, L.; Vakal, S.; Santana-Sanchez, A.; Hubacek, M.; Wang, Y.; Boehm, M.; Gutekunst, K.; Salminen, T. A.; Allahverdiyeva, Y.
10.1101/2023.05.19.541409 — plant biology — Posted on 2023-05-22
1497 GPX4-VIM equates a proliferating DTP state in TNBC subtypes with converged vulnerabilities to autophagy and glutathione inhibition.
Chaudhary, N.; Choudhary, B. S.; Patra, S.; Malvankar, S.; Shivashankar, A.; Jog, E.; Kailaje, V. K.; Khanna, S.; Manna, S.; Sahoo, S.; R, S.; Jolly, M. K.; Dalal, S. N.; Verma, N.
10.1101/2023.05.18.541287 — cancer biology — Posted on 2023-05-22
1498 Honeycomb-inspired SERS nano-bowls for rapid capture and analysis of extracellular vesicles and liposomes in suspension
Das, S.; Tinguely, J.-C.; Obuobi, S. A. O.; Guerreiro, E. M.; Skalko-Basnet, N.; Snir, O.; Saxena, K.; Ahluwalia, B. S.; Mehta, D. S.
10.1101/2023.05.18.541353 — biophysics — Posted on 2023-05-22
1505 Repeated Omicron infection alleviates SARS-CoV-2 immune imprinting
Yisimayi, A.; Song, W.; Wang, J.; Jian, F.; Yu, Y.; Chen, X.; Xu, Y.; Yang, S.; Niu, X.; Xiao, T.; Wang, J.; An, R.; Zhang, N.; Wang, Y.; Wang, P.; Zhao, L.; Sun, H.; Yu, L.; Gu, Q.; Shao, F.; Jin, R.; Shen, Z.; Xie, X. S.; Wang, Y.; Cao, Y.
10.1101/2023.05.01.538516 — immunology — Posted on 2023-05-22
1507 Parsing the effect of co-culture with brain organoids on Diffuse Intrinsic Pontine Glioma (DIPG) using quantitative proteomics
Prior, V.; Maksour, S.; Miellet, S.; Hulme, A.; Chen, Y.; Mirzaei, M.; Wang, Y.; Dottori, M.; O'Neill, G.
10.1101/2023.05.19.541551 — cancer biology — Posted on 2023-05-22
1509 An RNA origami robot that traps and releases a fluorescent aptamer
Sampedro Vallina, N.; McRae, E. K. S.; Geary, C.; Andersen, E. S.
10.1101/2023.05.19.541473 — bioengineering — Posted on 2023-05-22
1511 Extraocular muscle stem cells exhibit distinct cellular properties associated with non-muscle molecular signatures
Di Girolamo, D.; Benavente-Diaz, M.; Grimaldi, A.; Thomas Lopes, P.; Murolo, M.; Evano, B.; Gioftsidi, S.; Laville, V.; Mella, S.; Tajbakhsh, S.; Comai, G.
10.1101/2023.03.10.532049 — developmental biology — Posted on 2023-05-22
1514 Optimizing In Situ Proximity Ligation Assays for Mitochondria, ER, or MERC Markers in Skeletal Muscle Tissue and Cells
Stephens, D. C.; Crabtree, A.; Beasley, H. K.; Garza-Lopez, E.; Neikirk, K.; Mungai, M.; Vang, L.; Vue, Z.; Vue, N.; Marshall, A. G.; Turner, K.; Shao, J.-q.; Murray, S. A.; Gaddy, J. A.; Wanjalla, C.; Davis, J.; Damo, S. M.; Hinton, A.
10.1101/2023.05.20.541599 — cell biology — Posted on 2023-05-22
1515 Components of Isolated Skeletal Muscle Differentiated Through Antibody Validation
Stephens, D. C.; Mungai, M.; Crabtree, A.; Beasley, H. K.; Garza-Lopez, E.; Vang, L.; Neikirk, K.; Vue, Z.; Vue, N.; Marshall, A. G.; Turner, K.; Shao, J.-q.; Sarker, B.; Murray, S. A.; Gaddy, J. A.; Davis, J.; Damo, S. M.; Hinton, A.
10.1101/2023.05.20.541600 — cell biology — Posted on 2023-05-22
1516 Creating Optimal Conditions for OPA1 isoforms by Western Blot in Muscle Tissue
Stephens, D. C.; Crabtree, A.; Beasley, H. K.; Garza-Lopez, E.; Mungai, M.; Neikirk, K.; Vang, L.; Vue, Z.; Vue, N.; Marshall, A. G.; Turner, K.; Shao, J.-q.; Murray, S. A.; Gaddy, J. A.; Wanjalla, C.; Davis, J.; Damo, S. M.; Hinton, A.
10.1101/2023.05.20.541601 — cell biology — Posted on 2023-05-22
1517 Shell protein composition specified by NEAT1 domains dictates the formation of paraspeckles as distinct membraneless organelles
Takakuwa, H.; Yamazaki, T.; Souquere, S.; Adachi, S.; Yoshino, H.; Fujiwara, N.; Yamamoto, T.; Tohru, N.; Nakagawa, S.; Pierron, G.; Hirose, T.
10.1101/2023.05.21.541661 — cell biology — Posted on 2023-05-22
1518 Multicellular PD Control in Microbial Consortia
Martinelli, V.; Salzano, D.; Fiore, D.; di Bernardo, M.
10.1101/2023.03.22.533755 — synthetic biology — Posted on 2023-05-22
1520 CENTRE: A gradient boosting algorithm for Cell-type-specific ENhancer-Target pREdiction
Rapakoulia, T.; Lopez Ruiz de Vargas, S.; Omgba, P. A.; Laupert, V.; Ulitsky, I.; Vingron, M.
10.1101/2023.05.16.541035 — bioinformatics — Posted on 2023-05-22
1522 Long live the host! Proteomic analysis reveals possible strategies for parasitic manipulation of its social host
Hartke, J.; Ceron-Noriega, A.; Stoldt, M.; Sistermans, T.; Kever, M.; Fuchs, J.; Butter, F.; Foitzik, S.
10.1101/2022.12.23.521666 — evolutionary biology — Posted on 2023-05-22
1524 HDAC-6 inhibition ameliorates the early neuropathology in a mouse model of Krabbe disease
Braz, S. O.; Morgado, M. M.; Pereira, M. I.; Monteiro, A. C.; Golonzhka, O.; Jarpe, M.; Brites, P.; Sousa, M. M.; Nogueira-Rodrigues, J.
10.1101/2023.05.01.538924 — neuroscience — Posted on 2023-05-22
1526 Molecular Evolution and Interaction of 14-3-3 Proteins with H+-ATPases in Plant Abiotic Stresses
Jiang, W.; He, J.; Babla, M.; Wu, T.; Tong, T.; Riaz, A.; Zeng, F.; Qin, Y.; Chen, G.; Deng, F.; Chen, Z.-H.
10.1101/2023.05.18.541295 — plant biology — Posted on 2023-05-22
1527 GATA2 haploinsufficiency causes an epigenetic feedback mechanism resulting in myeloid and erythroid dysplasia
Gioacchino, E.; Zhang, W.; Koyunlar, C.; Zink, J.; de Looper, H.; Gussinklo, K. J.; Hoogenboezem, R.; Bosch, D.; Bindels, E.; Touw, I. P.; de Pater, E.
10.1101/2021.10.29.466416 — cancer biology — Posted on 2023-05-22
1533 Ancient and ongoing hybridization in the Oreochromis cichlid fishes
Ciezarek, A. G.; Mehta, T. K.; Man, A.; Ford, A.; Dorcas Kavembe, G.; Kasozi, N.; Ngatunga, B. P.; Shechonge, A. H.; Tamatamah, R.; Cnaani, A.; Di Palma, F.; Turner, G. F.; Genner, M. J.; Haerty, W.
10.1101/2023.05.19.541459 — evolutionary biology — Posted on 2023-05-22
1534 Changes in Cortical Directional Connectivity during Difficult Listening in Younger and Older Adults
Soleimani, B.; Karunathilake, I. M. D.; Das, P.; Kuchinsky, S. E.; Babadi, B.; Simon, J. Z.
10.1101/2023.05.19.541500 — neuroscience — Posted on 2023-05-22
1535 The Heritability of Human Connectomes: a Causal Modeling Analysis
Chung, J.; Bridgeford, E. W.; Powell, M.; Pisner, D.; Vogelstein, J. T.
10.1101/2023.04.02.532875 — neuroscience — Posted on 2023-05-22
1537 Altered grid-like coding in early blind people
Sigismondi, F.; Xu, Y.; Silvestri, M.; Bottini, R.
10.1101/2023.05.19.541468 — neuroscience — Posted on 2023-05-22
1538 StereoSiTE: A framework to spatially and quantitatively profile the cellular neighborhood organized iTME
Liu, X.; Qu, C.; Liu, C.; Zhu, N.; Huang, H.; Teng, F.; Huang, C.; Luo, B.; Liu, X.; Xu, Y.; Xie, M.; Xi, F.; Li, M.; Wu, L.; Li, Y.; Chen, A.; Xu, X.; Liao, S.; Zhang, J.
10.1101/2022.12.31.522366 — cancer biology — Posted on 2023-05-21
1543 Disentangling reference frames in the neural compass.
Dutriaux, L.; Xu, Y.; Sartorato, N.; Lhuillier, S.; Bottini, R.
10.1101/2023.05.21.541641 — neuroscience — Posted on 2023-05-21
1545 A cross-species proteomic map reveals neoteny of human synapse development
Wang, L.; Pang, K.; Zhou, L.; Cebrian-Silla, A.; Gonzalez-Granero, S.; Wang, S.; Bi, Q.; White, M. L.; Ho, B.; Li, J.; Li, T.; Perez, Y.; Huang, E. J.; Winkler, E. A.; Paredes, M. F.; Kovner, R.; Sestan, N.; Pollen, A. A.; Liu, P.; Li, J.; Piao, X.; Garcia-Verdugo, J. M.; Alvarez-Buylla, A.; Liu, Z.; Kriegstein, A. R.
10.1101/2022.10.24.513541 — neuroscience — Posted on 2023-05-22
1547 Optimized design and in vivo application of optogenetically functionalized Drosophila dopamine receptors
Zhou, F.; Tichy, A.-M.; Imambocus, B. N.; Rodriguez Jimenez, F. J.; Gonzalez Martinez, M.; Jahan, I.; Habib, M.; Wilhelmy, N.; Bräuler, V.; Lömker, T.; Sauter, K.; Helfrich-Förster, C.; Pielage, J.; Grunwald Kadow, I. C.; Janovjak, H.; Soba, P.
10.1101/2023.05.20.541404 — neuroscience — Posted on 2023-05-21
1548 SNAP25 disease mutations change the energy landscape for synaptic exocytosis due to aberrant SNARE interactions
Kadkova, A.; Murach, J.; Pedersen, M.; Malsam, A.; Malsam, J.; Soellner, T. H.; Sorensen, J. B.
10.1101/2023.05.21.541607 — neuroscience — Posted on 2023-05-21
1552 SQANTI3: curation of long-read transcriptomes for accurate identification of known and novel isoforms
Conesa, A.; Pardo-Palacios, F.; Arzalluz-Luque, A.; Kondratova, L.; Salguero, P.; Mestre-Tomas, J.; Amorin, R.; Liu, T.; Nanni, A.; McIntyre, L. M.; Tseng, E.
10.1101/2023.05.17.541248 — bioinformatics — Posted on 2023-05-21
1555 Oncogenic reactivation of young L1s is a hallmark of colon cancer
Neu, D.; Hung, S.; Bartels, C. F.; Faber, Z. J.; Lovrenert, K.; Pontius, W. D.; Morgan, L.; Chakraborty, M.; Liao, W.; Chin, D.; Hong, E. S.; Gray, J.; Moreno, V.; Kalady, M.; Peters, U.; Gryder, B.; Sallari, R. C.; Scacheri, P. C.
10.1101/2023.05.17.541189 — genomics — Posted on 2023-05-21
1558 Commonly used Bayesian diversification-rate models produce biologically meaningful differences on empirical phylogenies
Martinez-Gomez, J.; Song, M. J.; Tribble, C. M.; Kopperud, B. T.; Höhna, S.; Freyman, W. A.; Specht, C. D.; Rothfels, C. J.
10.1101/2023.05.17.541228 — evolutionary biology — Posted on 2023-05-21
1561 A complete morphological characterization of all life stages of the phorid fly M. scalaris
Pallavi, J.; Snehal, H.; Salazar, D.; Hanbar, M.; Chiramel, L. B.; Jha, K. A.; Kolipakala, R. S.; Venkatesh, S. B. L.; Shetty, T. D.; Madhusudan, N.; Mohan, A.; John, A.; D'souza, N. D.; Sheet, P.; Nagarajan, D.
10.1101/2023.05.18.541282 — zoology — Posted on 2023-05-21
1566 Cardiomyocyte-specific deletion of PTP1B protects against HFD-induced cardiomyopathy through direct regulation of cardiac metabolic signaling
Sun, Y.; Kontaridis, M. I.; Gao, Y.; Nelson, K.; Chanrasekhar, V.; Kamli-Salino, S.; Delibegovic, M.; Kessinger, C. W.; Tang, P.; Abel, E. D.
10.1101/2023.05.19.541546 — molecular biology — Posted on 2023-05-21
1568 Genomic, effector protein and culture-based analysis of Cyclaneusma minus in New Zealand provides evidence for multiple morphotypes
Tarallo, M.; Dobbie, K.; Nunes Leite, L.; Waters, T.; Gillard, K.; Sen, D.; McDougal, R. L.; Mesarich, C. H.; Bradshaw, R. E.
10.1101/2023.05.21.541640 — molecular biology — Posted on 2023-05-21
1571 Convergent mutations in phage virion assembly proteins enable evasion of Type I CBASS immunity
Richmond-Buccola, D.; Hobbs, S. J.; Garcia, J. M.; Toyoda, H.; Gao, J.; Shao, S.; Lee, A. S.; Kranzusch, P. J.
10.1101/2023.05.21.541620 — microbiology — Posted on 2023-05-21
1572 Reversing olorofim activity reveals multifactorial drug tolerance in Aspergillus fumigatus
Valero, C.; Mcmanus, M.; Ram Anna Durai, A.; Tindale, J.; Gago, S.; Bromley, M. J.
10.1101/2023.05.20.539046 — microbiology — Posted on 2023-05-21
1573 Disrupted memory T cell expansion in HIV-exposed uninfected infants is preceded by premature skewing of T cell receptor clonality.
Dzanibe, S.; Wilk, A. J.; Canny, S.; Ranganath, T.; Alinde, B.; Rubelt, F.; Huang, H.; Davis, M.; Holmes, S. P.; Jaspan, H. B.; Blish, C. A.; Gray, C. M.
10.1101/2023.05.19.540713 — immunology — Posted on 2023-05-21
1574 Aryl Hydrocarbon Receptor Suppresses Eosinophilic Esophagitis Responses through OVOL1 and SPINK7
Azouz, N. P.; Klingler, A. M.; Rochman, M.; Paul, M.; Caldwell, J. M.; Brusilovsky, M.; Dwyer, A. T.; Chen, X. P.; Miller, D.; Lynch, A.; Forney, C.; Kottyan, L.; Weirauch, M. T.; Rothenberg, M. E.
10.1101/2023.05.17.541192 — immunology — Posted on 2023-05-21
1577 On the role of melanistic coloration on thermoregulation in the crepuscular gecko Eublepharis macularius
Hastings, B. T.; Melnyk, A.; Ghyabi, M.; White, E.; Barroso, F. M.; Carretero, M. A.; Lattanzi, D.; Claude, J.; Chiari, Y.
10.1101/2023.05.18.541382 — zoology — Posted on 2023-05-21
1584 Multiplexed Volumetric CLEM enabled by antibody derivatives provides new insights into the cytology of the mouse cerebellar cortex
Han, X.; Lu, X.; Li, P. H.; Wang, S.; Schalek, R.; Meirovitch, Y.; Lin, Z.; Adhinarta, J.; Berger, D.; Wu, Y.; Fang, T.; Meral, E. S.; Asraf, S.; Ploegh, H.; Pfister, H.; Wei, D.; Jain, V.; Trimmer, J. S.; Lichtman, J. W.
10.1101/2023.05.20.540091 — neuroscience — Posted on 2023-05-21
1585 Recovery of a learned behavior despite partial restoration of neuronal dynamics after chronic inactivation of inhibitory neurons
Torok, Z.; Luebbert, L.; Feldman, J.; Duffy, A.; Nevue, A.; Wongso, S.; Mello, C.; Fairhall, A.; Pachter, L.; Gonzalez, W. G.; Lois, C.
10.1101/2023.05.17.541057 — neuroscience — Posted on 2023-05-21
1586 Latitudinal scaling of aggregation with abundance and its consequences for coexistence in species rich forests
Wiegand, T.; Wang, X.; Fischer, S.; Kraft, N. J. B.; Bourg, N. A.; Brockelman, W. Y.; Cao, M.; Chanthorn, W.; Chu, C.; Davies, S.; Ediriweera, S.; Gunatilleke, C. V. S.; Gunatilleke, I. A. U. N.; Hao, Z.; Howe, R.; Jiang, M.; Jin, G.; Kress, W. J.; Li, B.; Lian, J.; Lin, L.; Liu, F.; Ma, K.; McShea, W.; Mi, X.; Myers, J. A.; Nathalang, A.; Orwig, D. A.; Shen, G.; Su, S.-H.; Sun, I.-F.; Wang, X.; Wolf, A.; Yan, E.; Ye, W.; Zhu, Y.; Huth, A.
10.1101/2023.05.18.541254 — ecology — Posted on 2023-05-21
1587 Short- and long-term effects of continuous compost amendment on soil microbiome community
Cohen, J.; Zolti, A.; Rotbart, N.; Bar-Tal, A.; Laor, Y.; Medina, S.; Shawahna, R.; Saadi, I.; Raviv, M.; Green, S. J.; Yermiyahu, U.; Minz, D.
10.1101/2023.02.21.529350 — microbiology — Posted on 2023-05-21
1592 Win-paired cues modulate the effect of dopamine neuron sensitization on decision making and cocaine self-administration: divergent effects across sex
Hynes, T.; Chernoff, C.; Hrelja, K.; Tse, M.; Avarmidis, D.; Lysenko-Martin, M.; Calderhead, L.; Kaur, S.; Floresco, S.; Winstanley, C.
10.1101/2023.05.19.541413 — animal behavior and cognition — Posted on 2023-05-21
1594 Few temporally distributed brain connectivity states predict human cognitive abilities
Wehrheim, M. H.; Faskowitz, J.; Sporns, O.; Fiebach, C.; Kaschube, M.; Hilger, K.
10.1101/2022.12.23.521743 — neuroscience — Posted on 2023-05-21
1595 Mitochondrial Sodium/Calcium Exchanger (NCLX) Regulates Basal and Starvation-Induced Autophagy Through Calcium Signaling
de Miranda Ramos, V.; Serna, J. D.; Vilas-Boas, E. A.; Cabral-Costa, J. V.; da Cunha, F. M.; Kataura, T.; Korolchuk, V. I.; Kowaltowski, A. J.
10.1101/2023.03.17.533187 — cell biology — Posted on 2023-05-21
1600 Fast centromeric repeat turnover provides a glimpse into satellite DNA evolution in Nothobranchius annual killifishes
Volenikova, A.; Luksikova, K.; Mora, P.; Pavlica, T.; Altmanova, M.; Stundlova, J.; Pelikanova, S.; Simanovsky, S. A.; Jankasek, M.; Reichard, M.; Nguyen, P.; Sember, A.
10.1101/2023.03.23.534043 — genetics — Posted on 2023-05-21
1601 A local ATR-dependent checkpoint pathway is activated by a site-specific replication fork block in human cells
Ahmed-Seghir, S.; Jalan, M.; Grimsley, H. E.; Sharma, A.; Twayana, S.; Kosiyatrakul, S. T.; Thompson, C.; Schildkraut, C. L.; Powell, S. N.
10.1101/2023.03.26.534293 — molecular biology — Posted on 2023-05-21
1602 Multiplexed Volumetric CLEM enabled by antibody derivatives provides new insights into the cytology of the mouse cerebellar cortex
Han, X.; Lu, X.; Li, P. H.; Wang, S.; Schalek, R.; Meirovitch, Y.; Lin, Z.; Adhinarta, J.; Berger, D.; Wu, Y.; Fang, T.; Meral, E. S.; Asraf, S.; Ploegh, H.; Pfister, H.; Wei, D.; Jain, V.; Trimmer, J. S.; Lichtman, J. W.
10.1101/2023.05.20.540091 — neuroscience — Posted on 2023-05-21
1605 Distinct brain network features predict internalizing and externalizing traits in children and adults
Qu, Y. L.; Chen, J.; Tam, A.; Ooi, L. Q. R.; Dhamala, E.; Cocuzza, C.; Lawhead, C.; Yeo, B. T. T.; Holmes, A.
10.1101/2023.05.20.541490 — neuroscience — Posted on 2023-05-21
1607 CRISPR-based engineering of RNA viruses
Nemudryi, A.; Nemudraia, A.; Nichols, J. E.; Scherffius, A. M.; Zahl, T.; Wiedenheft, B. A.
10.1101/2023.05.19.541219 — molecular biology — Posted on 2023-05-20
1608 SF3B1-dependent alternative splicing is critical for maintaining endometrial homeostasis and the establishment of pregnancy
POPLI, P.; Chadchan, S. B.; Dias, M.; Deng, X.; Gunderson, S. J.; Jimenez, P.; Yalamanchili, H.; KOMMAGANI, R.
10.1101/2023.05.20.541590 — molecular biology — Posted on 2023-05-20
1612 Rat microbial biogeography and age-dependent lactic acid bacteria in healthy lungs
Zhao, L.; Cunningham, C.; Andruska, A. M.; Schimmel, K.; Ali, M. K.; Kim, D.; Gu, S.; Chang, J.; Spiekerkoetter, E.; Nicolls, M. R.
10.1101/2023.05.19.541527 — microbiology — Posted on 2023-05-20
1613 A scalable framework for high-throughput identification of functional origins of replication in non-model bacteria
Gilbert, C.; Brumwell, S. L.; Crits-Christoph, A.; Kang, S. C.; Martin-Moldes, Z.; Alsharif, W.; Esmurria, A.; Nguyen, M.-A.; Lee, H. H.; Ostrov, N.
10.1101/2023.05.19.541510 — synthetic biology — Posted on 2023-05-20
1615 The structure of NAD+ consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations.
Klontz, E.; Obi, J. O.; Wang, Y.; Glendening, G.; Carr, J.; Tsibouris, C.; Buddula, S.; Nallar, S.; Soares, A.; Beckett, D.; Redzic, J. S.; Eisenmesser, E.; Palm, C.; Schmidt, K.; Scudder, A.; Obiorah, T.; Essuman, K.; Milbrandt, J.; Diantonio, A.; Ray, K.; Snyder, M. L.; Deredge, D.; Snyder, G. A.
10.1101/2023.05.19.541320 — biochemistry — Posted on 2023-05-20
1619 Epitranscriptomics m6A analyses reveal distinct m6A marks under tumor necrosis α (TNF-α)-induced apoptotic conditions in HeLa cells
Alasar, A. A.; Tuncel, O.; Saglam, B.; Gazaloglu, Y.; Atbinek, M.; Cagiral, U.; Iscan, E.; Ozhan, G.; Akgul, B.
10.1101/2023.05.20.541583 — cell biology — Posted on 2023-05-20
1620 The regulation of Insulin/IGF-1 signaling by miR-142-3p associated with human longevity
Wang, X.; Jung, H. J.; Milholland, B.; Cui, J.; Tazearslan, C.; Atzmon, G.; Wang, X.; Yang, J.; Guo, Q.; Barzilai, N.; Robbins, P. D.; Suh, Y.
10.1101/2023.05.19.541542 — molecular biology — Posted on 2023-05-20
1621 Application of polystyrene sulfonate (PSS) for inhibiting toxicity of ALS/FTD-linked dipeptide repeats
Bratek-Skicki, A.; Ahmed, J.; Peeters, E.; Jonckheere, K.; Heeren, K.; Volkov, O.; Hendrix, J.; Batys, P.; Bosch, L. V. D.; Tompa, P.
10.1101/2023.05.19.541518 — molecular biology — Posted on 2023-05-20
1624 Iron Memory in E. coli
Bhattacharyya, S.; Bhattarai, N.; Pfannenstiel, D. M.; Wilkins, B.; Singh, A.; Harshey, R. M.
10.1101/2023.05.19.541523 — microbiology — Posted on 2023-05-20
1625 Engineering Programmable Material-To-Cell Pathways Via Synthetic Notch Receptors To Spatially Control Cellular Phenotypes In Multi-Cellular Constructs
Garibyan, M.; Hoffman, T.; Makaske, T.; Do, S.; March, A. R.; Cho, N.; Pedroncelli, N.; Lima, R. E.; Soto, J.; Jackson, B. A.; Khademhosseini, A.; Li, S.; McCain, M.; Morsut, L.
10.1101/2023.05.19.541497 — synthetic biology — Posted on 2023-05-20
1627 Cancer cells co-evolve with retrotransposons to mitigate viral mimicry
Sun, S.; Hong, J.; You, E.; Tsanov, K. M.; Chacon-Barahona, J.; Gioacchino, A. D.; Hoyos, D.; Li, H.; Jiang, H.; Ly, H.; Marhon, S. A.; Murali, R.; Chanda, P.; Karacay, A.; Vabret, N.; Carvalho, D. D.; LaCava, J.; Lowe, S. W.; Ting, D. T.; Iacobuzio-Donahue, C. A.; Solovyov, A.; Greenbaum, B. D.
10.1101/2023.05.19.541456 — cancer biology — Posted on 2023-05-20
1630 Cytosolic iron-sulfur protein assembly system identifies clients by a C-terminal tripeptide
Marquez, M. D.; Greth, C.; Buzuk, A.; Liu, Y.; Blinn, C. M.; Beller, S.; Leiskau, L.; Hushka, A.; Wu, K.; Nur, K.; Netz, D. J. A.; Perlstein, D. L.; Pierik, A. J.
10.1101/2023.05.19.541488 — biochemistry — Posted on 2023-05-20
1631 Nucleosome reorganisation in breast cancer tissues
Jacob, D. R.; Guiblet, W. M.; Mamayusupova, H.; Shtumpf, M.; Ruje, L.; Ciuta, I.; Gretton, S.; Correa, C.; Dellow, E.; Agrawal, S. P.; Shafiei, N.; Drobysevskaja, A.; Armstrong, C. M.; Lam, J. D. G.; Vainshtein, Y.; Clarkson, C. T.; Thorn, G. J.; Sohn, K.; Madapura, P. B.; Chandrasekharan, S.; Brooke, G. N.; Klenova, E.; Zhurkin, V. B.; Teif, V. B.
10.1101/2023.04.17.537031 — genomics — Posted on 2023-05-20
1632 Conserving a threatened North American walnut: a chromosome-scale reference genome for butternut (Juglans cinerea)
Guzman-Torres, C. R.; Trybulec, E.; LeVasseur, H.; Akella, H.; Amee, M.; Strickland, E.; Pauloski, N.; Williams, M.; Romero-Severson, J.; Hoban, S.; Woeste, K.; Pike, C.; Fetter, K. C.; Webster, C. N.; Neitzey, M. L.; O'Neill, R.; Wegrzyn, J. L.
10.1101/2023.05.12.539246 — genomics — Posted on 2023-05-20
1634 Flagellin is essential for initial attachment to mucosal surfaces by Clostridioides difficile
Sidner, B.; Lerma, A. I.; Biswas, B.; Ronish, L. A.; McCullough, H.; Auchtung, J. M.; Piepenbrink, K. H.
10.1101/2023.05.19.541533 — microbiology — Posted on 2023-05-20
1635 Origin of biogeographically distinct ecotypes during laboratory evolution
Baliga, N. S.; Valenzuela, J. J.; Immanuel, S. R. C.; Wilson, J.; Turkarslan, S.; Ruiz, M.; Gibbons, S. M.; Hunt, K. A.; Auer, M.; Zemla, M.; Stahl, D. A.
10.1101/2023.05.19.541524 — microbiology — Posted on 2023-05-20
1636 Infant and Adult Human Intestinal Enteroids are Morphologically and Functionally Distinct
Adeniyi-Ipadeola, G. O.; Hankins, J. D.; Kambal, A.; Zeng, X.-L.; Patil, K.; Poplaski, V.; Bomidi, C.; Nguyen-Phuc, H.; Grimm, S. L.; Coarfa, C.; Crawford, S. E.; Blutt, S. E.; Speer, A. L.; Estes, M. K.; Ramani, S.
10.1101/2023.05.19.541350 — microbiology — Posted on 2023-05-20
1638 Chemoenzymatic syntheses of fluorine-18-labeled disaccharides from FDG yield potent sensors of living bacteria in vivo
Sorlin, A.; Lopez Alvarez, M.; Rabbitt, S.; Alanizi, A.; Shuere, B.; Bobba, K. N.; Blecha, J.; Sakhamuri, S.; Evans, M.; Bayles, K. J.; Flavell, R.; Rosenberg, O.; Sriram, R.; Desmet, T.; Nidetzky, B.; Engel, J.; Ohliger, M.; Fraser, J.; Wilson, D. M.
10.1101/2023.05.20.541529 — microbiology — Posted on 2023-05-20
1639 Atypical B cells consist of subsets with distinct effector functions
Reyes, R. A.; Batugedara, G.; Dutta, P.; Reers, A.; Garza, R.; Ssewanyana, I.; Jagannathan, P.; Feeney, M. E.; Greenhouse, B.; Bol, S.; Ay, F.; Bunnik, E. M.
10.1101/2022.09.28.509955 — immunology — Posted on 2023-05-20
1644 Crystal ribcage: a platform for probing real-time lung function at cellular resolution in health and disease
Banerji, R.; Grifno, G. N.; Shi, L.; Smolen, D.; LeBourdais, R.; Muhvich, J.; Eberman, C.; Hiller, B.; Lee, J.; Regan, K.; Zheng, S.; Zhang, S. S.; Jiang, J.; Raslan, A. A.; Breda, J. C.; Pihl, R.; Traber, K.; Mazzilli, S.; Ligresti, G.; Mizgerd, J. P.; Suki, B.; Nia, H. T.
10.1101/2022.10.28.514251 — bioengineering — Posted on 2023-05-20
1647 13C tracer analysis reveals the landscape of metabolic checkpoints in human CD8+ T cell differentiation
Kirchmair, A.; Nemati, N.; Lamberti, G.; Trefny, M. P.; Krogsdam, A.; Siller, A.; Hörtnagl, P.; Schumacher, P.; Sopper, S.; Sandbichler, A. M.; Zippelius, A.; Ghesquiere, B.; Trajanoski, Z.
10.1101/2023.05.18.541159 — immunology — Posted on 2023-05-20
1648 Disrupted memory T cell expansion in HIV-exposed uninfected infants is preceded by premature skewing of T cell receptor clonality.
Dzanibe, S.; Wilk, A. J.; Canny, S.; Ranganath, T.; Alinde, B.; Rubelt, F.; Huang, H.; Davis, M.; Holmes, S. P.; Jaspan, H. B.; Blish, C. A.; Gray, C. M.
10.1101/2023.05.19.540713 — immunology — Posted on 2023-05-20
1649 Energy Guided Diffusion for Generating Neurally Exciting Images
Pierzchlewicz, P. A.; Willeke, K. F.; Nix, A. F.; Elumalai, P.; Restivo, K.; Shinn, T.; Nealley, C.; Rodriguez, G.; Patel, S.; Franke, K.; Tolias, A. S.; Sinz, F. H.
10.1101/2023.05.18.541176 — neuroscience — Posted on 2023-05-20
1650 Predicting gene level sensitivity to JAK-STAT signaling perturbation using a mechanistic-to-machine learning framework
Cheemalavagu, N.; Shoger, K. E.; Cao, Y. M.; Michalides, B. A.; Botta, S. A.; Faeder, J. R.; Gottschalk, R. A.
10.1101/2023.05.19.541151 — systems biology — Posted on 2023-05-20
1652 Noisy delay denoises biochemical oscillators
Song, Y.; Campbell, S.; Shiau, L.; Kim, J. K.; Ott, W.
10.1101/2023.05.17.541178 — systems biology — Posted on 2023-05-20
1653 Particulate matter composition drives differential molecular and morphological responses in lung epithelial cells
Engels, S. M.; Kamat, P.; Pafilis, G. S.; Li, Y.; Agrawal, A.; Haller, D. J.; Phillip, J. M.; Contreras, L. M.
10.1101/2023.05.17.541204 — systems biology — Posted on 2023-05-20
1654 Longitudinal analysis of a dietary mouse model of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH)
Saenz, M. M.; McDonough, J. C.; Bloom-Saldana, E.; Irimia, J. M.; Cauble, E. L.; Castillo, A.; Fueger, P. T.; Trevino, L. S.
10.1101/2023.05.19.540989 — physiology — Posted on 2023-05-20
1659 Enhancer status in the primitive endoderm supports unrestricted lineage plasticity in regulative development
Linneberg-Agerholm, M.; Sell, A. C.; Redo-Riveiro, A.; Proks, M.; Knudsen, T. E.; Perera, M.; Brickman, J. M.
10.1101/2023.05.20.540779 — developmental biology — Posted on 2023-05-20
1660 Regulation of RNA methylation by therapy treatment, promotes tumor survival
Bukhari, S. I. A.; Truesdell, S. S.; Datta, C.; Choudhury, P.; Wu, K. Q.; Shrestha, J.; Maharjan, R.; Plotsker, E.; Elased, R.; Laisa, S.; Bhambhani, V.; Lin, Y.; Kreuzer, J.; Morris, R.; Koh, S.-B.; Ellisen, L. W.; Haas, W.; Ly, A.; Vasudevan, S.
10.1101/2023.05.19.540602 — molecular biology — Posted on 2023-05-20
1663 Establishment of hairy root culture and its genetic transformation of Stephania tetrandra S. Moore for production of BIAs
Zhang, X.; Bu, J.; Zhao, Y.; Li, Q.; Li, X.; Ma, Y.; Tang, J.; Wang, J.; Lai, C.; Cui, G.; Guo, J.; Huang, L.
10.1101/2023.05.17.541101 — plant biology — Posted on 2023-05-20
1664 On-farm hatching and contact with adult hen post hatch induce sex-dependent effects on performance and welfare in broiler chickens
Guilloteau, L. A.; Bertin, A.; Crochet, S.; Bagnard, C.; Hondelatte, A.; Ravon, L.; Schouler, C.; Germain, K.; Collin, A.
10.1101/2023.05.17.541117 — physiology — Posted on 2023-05-20
1667 DNA hypermethylation and condensed chromatin correlate with chromosome-specific rRNA gene silencing in Arabidopsis
Mohannath, G.; McKinlay, A.; Enganti, R.; Puppala, N. V.; Saradadevi, G. P.; Pikaard, C.; Blevins, T.
10.1101/2023.02.03.526984 — plant biology — Posted on 2023-05-20
1668 Nanoscale engagement and clusterization of Programmed death ligand 1 (PD-L1) in the membrane lipid rafts of Non-Small Cell Lung Cancer cells
Ruglioni, M.; Civita, S.; Salvadori, T.; Cristiani, S.; Carnicelli, V.; Barachini, S.; Petrini, I.; Nepita, I.; Castello, M.; Diaspro, A.; Bianchini, P.; Storti, B.; Bizzarri, R.; Fogli, S.; Danesi, R.
10.1101/2022.08.09.503318 — biophysics — Posted on 2023-05-20
1673 Sex-specific effect of antenatal Zika virus infection on murine fetal growth, placental nutrient transporters, and nutrient sensor signaling pathways
Pereira-Carvalho, D.; Valim, A. C. C.; Andrade, C. B. V.; Bloise, E.; Dias, A. F.; Nascimento, V. M. O.; Silva Alves, R. K.; Lopes Brum, F.; Medeiros, I. G.; Coelho, S. V. A.; Arruda, L. B.; Todeschini, A. R.; Dias, W. B.; Ortiga-Carvalho, T. M.
10.1101/2023.03.30.534997 — physiology — Posted on 2023-05-20
1674 Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids
Lasolle, H.; Schiavo, A. A.; Tourneur, A.; Gillotay, P.; da Fonseca, B. d. F.; Ceolin, L.; Monestier, O.; Aganahi, B.; Chomette, L.; Kizys, M. M. L.; Haenebalcke, L.; Pieters, T.; Goossens, S.; Haigh, J.; Detours, V.; Maia, A. L.; Costagliola, S.; Romitti, M.
10.1101/2023.03.30.534915 — cancer biology — Posted on 2023-05-20
1676 Amplitude modulation pattern of rat distress vocalisations during fear conditioning
Gonzalez-Palomares, E.; Boulanger-Bertolus, J.; Dupin, M.; Mouly, A.-M.; Hechavarria, J. C.
10.1101/2023.01.18.524509 — animal behavior and cognition — Posted on 2023-05-20
1677 Generalized mutualisms promote range expansion in both plant and ant partners
Nathan, P.; Guenard, B.; Economo, E. P.; Simonsen, A.; Frederickson, M.
10.1101/2023.04.12.536632 — ecology — Posted on 2023-05-20
1678 Touch receptor end-organ innervation and function requires sensory expression of the transcription factor Meis2.
Desiderio, S.; Schwaller, F.; Tartour, K.; Padmanabhan, K.; Lewin, G. R.; Carroll, P.; Marmigere, F.
10.1101/2022.04.28.489889 — developmental biology — Posted on 2023-05-20
1679 A multifunctional Wnt regulator underlies the evolution of coat pattern in African striped mice
Johnson, M. R.; Li, S.; Guerrero-Juarez, C. F.; Miller, P.; Brack, B. J.; Mereby, S.; Feigin, C. Y.; Gaska, J.; Ploss, A.; Nie, Q.; Rivera-Perez, J. A.; Shvartsman, S. Y.; Mallarino, R.
10.1101/2022.12.12.520043 — developmental biology — Posted on 2023-05-20
1680 Circadian ribosome profiling reveals a role for the Period2 upstream open reading frame in sleep
Millius, A.; Yamada, R.; Fujishima, H.; Maeda, K.; Standley, D. M.; Sumiyama, K.; Perrin, D.; Ueda, H. R.
10.1101/2022.08.09.503391 — cell biology — Posted on 2023-05-20
1681 Toxin/Antitoxin Systems Induce Persistence and Work in Concert with Restriction/Modification Systems to Inhibit Phage
Fernandez-Garcia, L.; Song, S.; Kirigo, J.; Battisti, M. E.; Huelgas-Mendez, D.; Garcia-Contreras, R.; Petersen, M. E.; Tomas, M.; Wood, T. K.
10.1101/2023.02.25.529695 — molecular biology — Posted on 2023-05-20
1683 Antibiotics promote intestinal growth of carbapenem-resistant Enterobacteriaceae by enriching nutrients and depleting microbial metabolites
Yip, A. Y. G.; King, O. G.; Omelchenko, O.; Kurkimat, S.; Horrocks, V.; Mostyn, P.; Danckert, N.; Ghani, R.; Satta, G.; Jauneikaite, E.; Davies, F. J.; Clarke, T. B.; Mullish, B. H.; Marchesi, J. R.; McDonald, J. A. K.
10.1101/2023.03.25.533086 — microbiology — Posted on 2023-05-20
1684 TREM2 is downregulated by HSV1 in microglia and involved in antiviral defense in the brain
Fruhwurth, S.; Reinert, L.; Oberg, C.; Sakr, M.; Henricsson, M.; Zetterberg, H.; Paludan, S.
10.1101/2023.03.16.532882 — immunology — Posted on 2023-05-20
1685 Altered glucose utilization and disrupted mitochondrial homeostasis in CD4+ T cells from HIV-positive women on combination anti-retroviral therapy
Akiso, M.; Ameka, M.; Naidoo, K.; Langat, R.; Kombo, J.; Sikuku, D.; Ndung'u, T.; Altfeld, M.; Anzala, O.; Mureithi, M.
10.1101/2023.05.17.541113 — immunology — Posted on 2023-05-20
1686 The mitochondrial matrix protein cyclophilin D contributes to deficits in parvalbumin interneurons in schizophrenia
O'Brien, J. T.; Jalilvand, S. P.; Suji, N. A.; Phensy, A.; Jupelly, R. K.; Mwirigi, J. M.; Elahi, H.; Price, T. J.; Kroener, S.
10.1101/2023.05.19.541499 — neuroscience — Posted on 2023-05-20
1687 Planning to revisit: neural activity in refixation precursors
Nikolaev, A. R.; Ehinger, B. V.; Meghanathan, R. N.; van Leeuwen, C.
10.1101/660308 — neuroscience — Posted on 2023-05-20
1688 An atlas and database of neuropeptide gene expression in the adult zebrafish forebrain
Hiraki-Kajiyama, T.; Miyasaka, N.; Ando, R.; Wakisaka, N.; Itoga, H.; Onami, S.; Yoshihara, Y.
10.1101/2023.03.29.534505 — neuroscience — Posted on 2023-05-20
1689 Recovery of a learned behavior despite partial restoration of neuronal dynamics after chronic inactivation of inhibitory neurons
Torok, Z.; Luebbert, L.; Feldman, J.; Duffy, A.; Nevue, A.; Wongso, S.; Mello, C.; Fairhall, A.; Pachter, L.; Gonzalez, W. G.; Lois, C.
10.1101/2023.05.17.541057 — neuroscience — Posted on 2023-05-20
1690 Intense light unleashes male-male courtship behaviorin wild-type Drosophila
Ueda, A.; Berg, A.; Khan, T.; Ruzicka, M.; Li, S.; Cramer, E.; Iyengar, A.; Wu, C.-F.
10.1101/2022.07.12.499756 — neuroscience — Posted on 2023-05-20
1691 Experience-Dependent Plasticity in Nucleus Laminaris of the Barn Owl
Carr, C. E.; Wang, T.; Kraemer, I.; Capshaw, G.; Ashida, G.; Koeppl, C.; Kempter, R.; Kuokkanen, P. T.
10.1101/2023.02.02.526884 — neuroscience — Posted on 2023-05-20
1693 Tomato CYP94C1 terminates jasmonate signaling during fruit ripening by inactivating bioactive jasmonoyl-L-isoleucine
Yang, T.; Deng, L.; Sun, C.; Ali, M.; Wu, F.; Zhai, H.; Xu, Q.; Xin, P.; Chu, J.; Huang, T.; Li, C.-B.; Li, C.
10.1101/2023.05.17.541065 — plant biology — Posted on 2023-05-19
1695 Phosphate starvation response precedes abscisic acid response under progressive mild drought in plants
Nagatoshi, Y.; Ikazaki, K.; Kobayashi, Y.; Mizuno, N.; Sugita, R.; Takebayashi, Y.; Kojima, M.; Sakakibara, H.; Kobayashi, N. I.; Tanoi, K.; Fujii, K.; Baba, J.; Ogiso-Tanaka, E.; Ishimoto, M.; Yasui, Y.; Oya, T.; Fujita, Y.
10.1101/2021.07.28.453724 — plant biology — Posted on 2023-05-20
1697 Drosophila AHR limits tumor growth and stem cell proliferation in the intestine
Tsai, M.; Sun, J.; Alexandre, C.; Shapiro, M.; Franchet, A.; Li, Y.; Gould, A. P.; Vincent, J.-P.; Stockinger, B.; Diny, N. L.
10.1101/2023.05.17.538815 — cancer biology — Posted on 2023-05-19
1698 D-SPIN constructs gene regulatory network models from multiplexed scRNA-seq data revealing organizing principles of cellular perturbation response
Jiang, J.; Chen, S.; Tsou, T.; McGinnis, C. S.; Khazaei, T.; Zhu, Q.; Park, J. H.; Strazhnik, I.-M.; Hanna, J.; Chow, E. D.; Sivak, D. A.; Gartner, Z. J.; Thomson, M.
10.1101/2023.04.19.537364 — bioinformatics — Posted on 2023-05-20
1699 Multivariate adaptive shrinkage improves cross-population transcriptome prediction for transcriptome-wide association studies in underrepresented populations
Araujo, D. S.; Nguyen, C.; Hu, X.; Mikhaylova, A. V.; Gignoux, C.; Ardlie, K. G.; Taylor, K. D.; Durda, P.; Liu, Y.; Papanicolaou, G.; Cho, M. H.; Rich, S. S.; Rotter, J. I.; NHLBI TOPMed Consortium, ; Im, H. K.; Manichaikul, A. W.; Wheeler, H. E.
10.1101/2023.02.09.527747 — genomics — Posted on 2023-05-20
1701 Native extracellular matrix promotes human neuromuscular organoid morphogenesis and function.
Auletta, B.; Rossi, L.; Cecchinato, F.; Barbato, G.; Lauroja, A.; Chiolerio, P.; Cecconi, G.; Maghin, E.; Easler, M.; Raffa, P.; Angiolillo, S.; Qin, W.; Calabro, S.; Villa, C.; Gagliano, O.; Laterza, C.; Cacchiarelli, D.; Cescon, M.; Giomo, M.; Torrente, Y.; Luni, C.; Piccoli, M.; Elvassore, N.; Urciuolo, A.
10.1101/2023.05.19.541464 — cell biology — Posted on 2023-05-20
1702 Importin 13-dependent Axon Diameter Growth Regulates Conduction Speeds along Myelinated CNS Axons
Bin, J. M.; Suminaite, D.; Benito--Kwiecinski, S.; Kegel, L.; Rubio-Brotons, M.; Early, J. J.; Soong, D.; Livesey, M. R.; Poole, R. J.; Lyons, D.
10.1101/2023.05.19.541431 — neuroscience — Posted on 2023-05-19
1704 Analysis of the Confidence in the Prediction of the Protein Folding by Artificial Intelligence
Tejera-Nevado, P.; Serrano, E.; Gonzalez-Herrero, A.; Bermejo-Moreno, R.; Rodriguez-Gonzalez, A.
10.1101/2023.05.17.540933 — bioinformatics — Posted on 2023-05-19
1705 DNA methylation-environment interactions in the human genome
Johnston, R. A.; Aracena, K. A.; Barreiro, L. B.; Lea, A. J.; Tung, J.
10.1101/2023.05.19.541437 — genomics — Posted on 2023-05-19
1708 Severe enamel defects in wild Japanese macaques
Towle, I.; Loch, C.; Martinez de Pinillos, M.; Modesto-Mata, M.; Hlusko, L. J.
10.1101/2023.05.18.541087 — ecology — Posted on 2023-05-19
1709 A Hypothalamic Circuit Underlying the Dynamic Control of Social Homeostasis
Liu, D.; Rahman, M.; Johnson, A.; Tsutsui-Kimura, I.; Pena, N.; Talay, M.; Logeman, B. L.; Finkbeiner, S.; Choi, S.; Capo-Battaglia, A.; Abdus-Saboor, I.; Ginty, D. D.; Uchida, N.; Watabe-Uchida, M.; Dulac, C.
10.1101/2023.05.19.540391 — neuroscience — Posted on 2023-05-19
1710 Functional brain connectivity during social attention predicts individual differences in social skill
Brindley, S. R.; Skyberg, A. M.; Graves, A. J.; Connelly, J. J.; Puglia, M. H.; Morris, J. P.
10.1101/2023.05.19.541349 — neuroscience — Posted on 2023-05-19
1711 The CaliAli tool for long-term tracking of neuronal population dynamics in calcium imaging
Vergara, P.; Wang, Y.; Srinivasan, S.; Cherasse, Y.; Naoi, T.; Sugaya, Y.; Sakurai, T.; Kano, M.; Sakaguchi, M.
10.1101/2023.05.19.540935 — neuroscience — Posted on 2023-05-19
1715 Subtype-specific circadian clock dysregulation modulates breast cancer biology, invasiveness, and prognosis.
Hammarlund, J. A.; Li, S.-Y.; Wu, G.; Lian, J.-W.; Howell, S. J.; Clarke, R.; Adamson, A.; Goncalves, C. F.; Hogenesch, J. B.; Meng, Q.-J. A.; Anafi, R. C.
10.1101/2023.05.17.540386 — cancer biology — Posted on 2023-05-19
1718 Virtual reality empowered deep learning analysis of brain activity
Kaltenecker, D.; Al-Maskari, R.; Negwer, M.; Hoeher, L.; Kofler, F.; Zhao, S.; Todorov, M. T.; Paetzold, J. C.; Wiestler, B.; Geppert, J.; Morigny, P.; Rohm, M.; Menze, B. H.; Herzig, S.; Berriel Diaz, M.; Erturk, A.
10.1101/2023.05.18.540970 — bioinformatics — Posted on 2023-05-19
1721 Autoreactive B cells in rheumatoid arthritis consist of activated CXCR3+ memory B cells and plasmablasts
Reijm, S.; Kwekkeboom, J. C.; Blomberg, N. J.; Suurmond, J.; van der Woude, D.; Toes, R. E.; Scherer, H. U.
10.1101/2023.05.19.538699 — immunology — Posted on 2023-05-19
1722 Incorporating uncertainty within dynamic interoceptive learning
Brand, K.; Wise, T.; Hess, A. J.; Russell, B. R.; Stephan, K. E.; Harrison, O. K.
10.1101/2023.05.19.538717 — neuroscience — Posted on 2023-05-19
1728 Genomic and metabolic plasticity drive alternative scenarios for adapting Pseudomonas putida to non-native substrate D-xylose.
Dvorak, P.; Buryskova, B.; Popelarova, B.; Ebert, B. E.; Botka, T.; Bujdos, D.; Sanchez-Pascuala, A.; Schoettler, H.; Hayen, H.; de Lorenzo, V.; Blank, L. M.; Benesik, M.
10.1101/2023.05.19.541448 — bioengineering — Posted on 2023-05-19
1729 Prime editing of the beta-1 adrenoceptor in the brain reprograms mouse behavior
Boeck, D.; Tidecks, L.; Wilhelm, M.; Weber, Y.; Ioannidi, E.; Mumenthaler, J.; Rothgangl, T.; Schmidheini, L.; Janjuha, S.; Patriarchi, T.; Schwank, G.
10.1101/2023.05.19.541410 — genetics — Posted on 2023-05-19
1730 Characterisation of the genetic determinants of context specific DNA methylation in primary monocytes
Gilchrist, J. P.; Fang, H.; Danielli, S.; Tomkova, M.; Nassiri, I.; Ng, E.; Tong, O.; Taylor, C. A.; Al-Mossawi, H. H.; Lau, E. K.; Neville, M. J.; Schuster-Bockler, B.; Knight, J. C.; Fairfax, B. P.
10.1101/2023.05.17.541041 — genetics — Posted on 2023-05-19
1731 Praziquantel inhibits Caenorhabditis elegans development and species-wide differences might be cct-8-dependent
Wit, J.; Dilks, C. M.; Zhang, G.; Guisbert, K. S. K.; Zdraljevic, S.; Guisbert, E.; Andersen, E. C.
10.1101/2023.05.17.541211 — genetics — Posted on 2023-05-19
1735 Mutant Ppbbx24-del gene positively regulates light-induced anthocyanin accumulation in the red pear
Li, S.; Ou, C.; Wang, F.; Zhang, Y.; Ismail, O.; Abd Elaziz, Y. S. G.; Edris, S.; Jiang, S.; Li, H.
10.1101/2023.05.19.541476 — molecular biology — Posted on 2023-05-19
1739 Antigenic mapping of the hemagglutinin of the H9 subtype influenza A viruses using sera from Japanese quail (Coturnix c. japonica).
Carnaccini, S.; Caceres, C. J.; Gay, L. C.; Ferreri, L.; Skepner, E.; Burke, D. F.; Brown, I. H.; Geiger, G.; Obadan, A.; Rajao, D. S.; Lewis, N. S.; Perez, D. R.
10.1101/2023.05.18.541344 — microbiology — Posted on 2023-05-19
1740 Homeostatic, repertoire and transcriptional relationships between colon T regulatory cell subsets
Ramanan, D.; Chowdhary, K.; Candeias, S. M.; Sassone-Corsi, M.; Mathis, D.; Benoist, C.
10.1101/2023.05.17.541199 — immunology — Posted on 2023-05-19
1741 Shaping Synthetic Multicellular and Complex Multimaterial Tissues via Embedded Extrusion Volumetric Printing of Microgels
Ribezzi, D.; Gueye, M.; Florczak, S.; Dusi, F.; de Vos, D.; Manente, F.; Hierholzer, A.; Fussenegger, M.; Caiazzo, M.; Blunk, T.; Malda, J.; Levato, R.
10.1101/2023.05.17.541111 — bioengineering — Posted on 2023-05-19
1742 Engineering 3D neuronal networks with directional endogenous neuronal plasticity pathways
Pagan Diaz, G. J.; Kilacarslan, E. A.; Wester, M.; Rahman, S.; Aydin, O.; Gapinske, L.; Kim, Y.; Buoros, D.; Saif, M. T. A.; Bashir, R.
10.1101/2023.05.17.540876 — bioengineering — Posted on 2023-05-19
1743 Sterols from cholesterol synthesis control distinct gene regulatory pathways
Skubic, C.; Trcek, H.; Nassib, P.; Walakira, A.; Pohar, K.; Petek, S.; Rezen, T.; Ihan, A.; Rozman, D.
10.1101/2023.05.19.538399 — biochemistry — Posted on 2023-05-19
1744 Molecular archaeology: individual human DNA and infection profiles from 100 year old mosquitoes
Crombe, F.; Nagi, S. C.; Tomas, E. V.; Charlwood, J. D.; Donnelly, M. J.; Weetman, D.
10.1101/2023.05.19.541455 — genetics — Posted on 2023-05-19
1746 The emergence and diversification of a zoonotic pathogen from within the microbiota of intensively farmed pigs
Murray, G. G. R.; Hossain, A. S. M. M.; Miller, E.; Bruchmann, S.; Balmer, A. J.; Matuszewska, M.; Herbert, J.; Hadjirin, N. F.; Mugabi, R.; Li, G.; Ferrando, M. L.; Fernades de Oliveira, I. M.; Nguyen, T.; Yen, P. L. K.; Moe, A. Z.; Wai, T. S.; Gottschalk, M.; Aragon, V.; Valentin-Weigand, P.; Heegaard, P. M. H.; Vrieling, M.; Maw, M. T.; Myint, H. T.; Win, Y. T.; Hoa, N. T.; Bentley, S. D.; Clavijo, M. J.; Wells, J. M.; Tucker, A. D.; Weinert, L. A.
10.1101/2023.05.17.540811 — evolutionary biology — Posted on 2023-05-19
1747 A severe bottleneck impacted the genomic structure of egg-eating cichlids
Imamoto, M.; Nakamura, H.; Aibara, M.; Hatashima, R.; Itoh, T.; Nikaido, M.
10.1101/2023.05.17.541056 — evolutionary biology — Posted on 2023-05-19
1751 Global diversity of enterococci and description of 18 novel species
Schwartzman, J. A.; Lebreton, F.; Salamzade, R.; Martin, M. J.; Schaufler, K.; Urhan, A.; Abeel, T.; Camargo, I. L. B. C.; Sgardioli, B. F.; Prichula, J.; Frazzon, A. P. G.; Van Tyne, D.; Treinish, G.; Innis, C. J.; Wagenaar, J. A.; Whipple, R. M.; Manson, A. L.; Earl, A. M.; Gilmore, M. S.
10.1101/2023.05.18.540996 — microbiology — Posted on 2023-05-19
1752 Uracil-DNA Glycosylase of Murine Gammaherpesvirus 68 Binds Cognate Viral Replication Factors Independently of its Catalytic Residues
Smith, K. R.; Paul, S.; Dong, Q.; Anannya, O.; Oldenburg, D. G.; Forrest, J. C.; McBride, K. M.; Krug, L. T.
10.1101/2023.05.19.541466 — microbiology — Posted on 2023-05-19
1754 Fascin-induced bundling protects actin filaments from disassembly by cofilin
Chikireddy, J.; Lengagne, L.; Le Borgne, R.; Wioland, H.; Romet-Lemonne, G.; Jegou, A.
10.1101/2023.05.19.541460 — biochemistry — Posted on 2023-05-19
1756 Tissue-intrinsic Wnt signals antagonize Nodal-driven AVE differentiation
Schumacher, S.; Fernkorn, M.; Marten, M.; Kim, Y. S.; Bedzhov, I.; Schroter, C.
10.1101/2023.05.19.541432 — developmental biology — Posted on 2023-05-19
1757 Native extracellular matrix promotes human neuromuscular organoid morphogenesis and function.
Urciuolo, A.; Auletta, B.; Rossi, L.; Cecchinato, F.; Barbato, G.; Lauroja, A.; Chiolerio, P.; Cecconi, G.; Maghin, E.; Easler, M.; Raffa, P.; Angiolillo, S.; Qin, W.; Calabro, S.; Villa, C.; Gagliano, O.; Laterza, C.; Cacchiarelli, D.; Cescon, M.; Giomo, M.; Torrente, Y.; Luni, C.; Piccoli, M.; Elvassore, N.
10.1101/2023.05.19.541464 — cell biology — Posted on 2023-05-19
1760 Lactylation-driven FTO-mediated m6A modification of CDK2 aggravates diabetic microvascular anomalies
Chen, X.; Sun, R.-X.; Wang, J.-N.; Zhang, Y.-R.; Qin, B.; Zhang, Y.-C.; Dai, Y.-X.; Zhu, H.-J.; Wang, Y.; Zhao, J.-X.; Zhang, W.-W.; Ji, J.; Yuan, S.-T.; Shen, Q.-D.; Liu, Q.-H.
10.1101/2023.05.19.541470 — cell biology — Posted on 2023-05-19
1761 Highly structured genomic sequences mediate the function of a RNA virus polymerase.
Ward, J. C.; Lasecka-Dykes, L.; Dobson, S. J.; Gold, S.; Kingston, N. J.; Herod, M. R.; King, D. P.; Tuthill, T. J.; Rowlands, D. J.; Stonehouse, N. J.
10.1101/2023.04.26.538422 — molecular biology — Posted on 2023-05-19
1765 AlphaFold predictions are valuable hypotheses, and accelerate but do not replace experimental structure determination
Terwilliger, T. C.; Leibschner, D. L.; Croll, T.; Williams, C. J.; McCoy, A. J.; Poon, B. K.; Afonine, P.; Oeffner, R. D.; Richardson, J. S.; Read, R. J.; Adams, P. D.
10.1101/2022.11.21.517405 — biochemistry — Posted on 2023-05-19
1766 Models to Estimate Genetic Gain of Soybean Seed Yield from Annual Multi-Environment Field Trials
Dalsente Krause, M.; Piepho, H.-P.; Dias Olimpio das Gracas, K.; Singh, A. K.; Beavis, W. D.
10.1101/2023.05.13.540664 — genetics — Posted on 2023-05-19
1769 Molecular Determinants of Calcitriol Signaling and Sensitivity in Glioma Stem-like Cells
Rehbein, S.; Possmayer, A.-L.; Bozkurt, S.; Lotsch, C.; Gerstmeier, J.; Burger, M.; Momma, S.; Maletzki, C.; Classen, C.-F.; Freiman, T. M.; Dubinski, D.; Lamszus, K.; Day, B. W.; Stringer, B. W.; Herold-Mende, C.; Münch, C.; Kögel, D.; Linder, B.
10.1101/2023.05.16.540926 — cancer biology — Posted on 2023-05-19
1772 Acidification-dependent suppression of C. difficile by enterococci in vitro
Smith, H. R.; Wood, A. K.; Johnson, A.; Stern, A. Z.; Sikander, Z.; Gutierrez, L.-H.; Agosto, A. A.; McKenney, P. T.
10.1101/2023.05.16.541032 — microbiology — Posted on 2023-05-19
1774 Uncovering strain- and age-dependent differences in innate immune response to SARS-CoV-2 infection in nasal epithelia using 10X single-cell sequencing
Chang, J. J.-Y.; Grimley, S.; Tran, B.; Deliyannis, G.; Tumpach, C.; Steinig, E. J.; Wong, S. L.; Waters, S. A.; Stinear, T. P.; Pitt, M. E.; Purcell, D. F. J.; Vincan, E.; Coin, L. J. M.
10.1101/2023.03.04.531075 — immunology — Posted on 2023-05-19
1775 Enhanced Airway Epithelial Response to SARS-CoV-2 Infection in Children is Critically Tuned by the Cross-Talk Between Immune and Epithelial Cells
Goncalves Magalhaes, V.; Lukassen, S.; Drechsler, M.; Loske, J.; Burkart, S. S.; Wüst, S.; Jacobsen, E.-M.; Röhmel, J.; Mall, M. A.; Debatin, K.-M.; Eils, R.; Autenrieth, S.; Janda, A.; Lehmann, I.; Binder, M.
10.1101/2023.05.17.541103 — immunology — Posted on 2023-05-19
1776 TREM2 promotes glioma progression and angiogenesis mediated by microglia/brain macrophages
Chen, X.; Zhao, Y.; Huang, Y.; Zhu, K.; Zeng, F.; Zhao, J.; Zhang, H.; Zhu, X.; Kettenmann, H.; Xiang, X.
10.1101/2023.05.18.540621 — neuroscience — Posted on 2023-05-19
1777 Novel Pan-RAS Inhibitor ADT-007 Induces Tumor Regression in Mouse Models of GI Cancer
Foote, J.; Mattox, T. E.; Keeton, A. B.; Smith, F. T.; Berry, K. L.; Ward, A. B.; Yoon, K. J.; Sarvesh, S.; Nagaraju, G. P.; Maxuitenko, Y.; Chen, X.; Valiyaveettil,, J.; Carstens, J. L.; Yang, J.; Yang, J.; Buchsbaum, D. J.; Zhou, G.; Nurmmedov, E.; Babic, I.; Gaponenko, V.; Abdelkarim, H.; Boyd, M. R.; El-Rayes, B. F.; Piazza, G. A.
10.1101/2023.05.17.541233 — cancer biology — Posted on 2023-05-19
1779 Living cell mTORC1 inhibition reporter mTIR reveals nutrient-sensing targets of histone deacetylase inhibitor
Xie, X.; Li, C.; Ouyang, Y.; Lu, C.; Chen, F.; Yi, Y.; Peng, S.; Wang, Y.; Chen, X.; Yan, X.; Li, S.; Feng, L.
10.1101/2023.05.19.541400 — cell biology — Posted on 2023-05-19
1780 Senescent cells in Giant Cell Arteritis have inflammatory phenotype participating in tissue injury via IL-6 dependent pathways
Veroutis, D.; Argyropoulou, O. D.; Goules, A. V.; Kambas, K.; Palamidas, D. A.; Evangelou, K.; Havaki, S.; Polyzou, A.; Xingi, E.; Karatza, E.; Kyriaki, B. A.; Cavazza, A.; Kittas, C.; Thanos, D.; Ricordi, C.; Marvisi, C.; Muratore, F.; Galli, E.; Croci, S.; Salvarani, C.; Gorgoulis, V. G.; Tzioufas, A. G.
10.1101/2023.05.19.541093 — cell biology — Posted on 2023-05-19
1781 Adaptive Pathfinding by Nucleokinesis during Amoeboid Migration
Kroll, J.; Hauschild, R.; Stefanowski, K.; Hermann, M. D.; Merrin, J.; Shafeek, L.; Mueller-Taubenberger, A.; Renkawitz, J.
10.1101/2023.05.19.540965 — cell biology — Posted on 2023-05-19
1784 Key Genetic Determinants Driving Esophageal Squamous Cell Carcinoma Initiation and Immune Evasion
Ko, K.-P.; Huang, Y.; Zhang, S.; Zou, G.; Kim, B.; Zhang, J.; Jun, S.; Martin, C.; Dunbar, K. J.; Efe, G.; Rustgi, A. K.; Nakagawa, H.; Park, J.-I.
10.1101/2022.10.13.512143 — cancer biology — Posted on 2023-05-18
1790 PCBP1 regulates alternative splicing of AARS2 in congenital cardiomyopathy
Lu, Y. W.; Liang, Z.; Guo, H.; Fernandes, T.; Espinoza-Lewis, R. A.; Wang, T.; Li, K.; Li, X.; Singh, G. B.; Wang, Y.; Cowan, D. B.; Mably, J. D.; Philpott, C. C.; Chen, H.; Wang, D.-Z.
10.1101/2023.05.18.540420 — developmental biology — Posted on 2023-05-18
1794 CRB3 navigates Rab11 trafficking vesicles to promote γTuRC assembly during ciliogenesis
Wang, B.; Liang, Z.; Tan, T.; Zhang, M.; Jiang, Y.; Shang, Y.; Gao, X.; Song, S.; Wang, R.; Chen, H.; Liu, J.; Li, J.; Ren, Y.; Liu, P.
10.1101/2023.02.15.528649 — cell biology — Posted on 2023-05-18
1796 Correlating Deep Learning-Based Automated Reference Kidney Histomorphometry with Patient Demographics and Creatinine
Ginley, B.; Lucarelli, N.; Zee, J.; Jain, S.; Han, S. S.; Rodrigues, L.; Ozrazgat-Baslanti, T.; Wong, M. L.; Nadkarni, G.; Jen, K.-Y.; Sarder, P.
10.1101/2023.05.18.541348 — cell biology — Posted on 2023-05-18
1799 Distinct Local and Global Functions of Aβ Low-Threshold Mechanoreceptors in Mechanical Pain Transmission
Gautam, M.; Yamada, A.; Yamada, A. I.; Wu, Q.; Kridsada, K.; Ling, J.; Yu, H.; Dong, P.; Ma, M.; Gu, J.; Luo, W.
10.1101/2023.05.16.540962 — neuroscience — Posted on 2023-05-18
1800 Neural dynamics and geometry for transitive inference
Kay, K.; Biderman, N.; Khajeh, R.; Beiran, M.; Cueva, C. J.; Shohamy, D.; Jensen, G.; Wei, X.-X.; Ferrera, V. P.; Abbott, L. F.
10.1101/2022.10.10.511448 — neuroscience — Posted on 2023-05-18
1802 Music Affects State Anxiety and Brain Connectivity
Pedersen, M.; Shepherd, D.; Vashista, G.; Kercher, A.; Hautus, M. J.
10.1101/2023.05.18.541357 — neuroscience — Posted on 2023-05-18
1803 A Unifying Principle for the Functional Organization of Visual Cortex
Margalit, E.; Lee, H.; Finzi, D.; DiCarlo, J. J.; Grill-Spector, K.; Yamins, D. L. K.
10.1101/2023.05.18.541361 — neuroscience — Posted on 2023-05-18
1804 Maize integrates light and volatile cues from neighboring plants into stronger defense responses
Escobar-Bravo, R.; Schimmel, B. C.; Zhang, Y.; Wang, L.; Robert, C. A.; Glauser, G.; Ballare, C. L.; Erb, M.
10.1101/2022.09.12.507519 — plant biology — Posted on 2023-05-18
1807 Neural population dynamics reveals disruption of spinal sensorimotor computations during electrical stimulation of sensory afferents
Katic Secerovic, N.; Balaguer, J.-M.; Gorskii, O.; Pavlova, N.; Liang, L.; Ho, J.; Grigsby, E.; Gerszten, P. C.; Karal-ogly, D.; Bulgin, D.; Orlov, S.; Pirondini, E.; Musienko, P.; Raspopovic, S.; Capogrosso, M.
10.1101/2021.11.19.469209 — neuroscience — Posted on 2023-05-18
1810 Microsecond dynamics control the HIV-1 envelope conformation
Bennett, A. L.; Edwards, R. J.; Kosheleva, I.; Saunders, C.; Bililign, Y.; Williams, A.; Manosouri, K.; Saunders, K. O.; Haynes, B. F.; Acharya, P.; Henderson, R.
10.1101/2023.05.17.541130 — biophysics — Posted on 2023-05-18
1811 Evaluation of a deuterated triarylmethyl spin probe for in vivo R2*-based EPR oximetric imaging with enhanced dynamic range
Kishimoto, S.; Devasahayam, N.; Chandramouli, G. V.; Murugesan, R.; Otowa, Y.; Yamashita, K.; Yamamoto, K.; Brender, J. R.; Krishna, M. C.
10.1101/2023.05.18.541366 — biophysics — Posted on 2023-05-18
1812 Identification of the bacteriophage nucleus protein interaction network
Enustun, E.; Deep, A.; Gu, Y.; Nguyen, K. T.; Chaikeeratisak, V.; Armbruster, E.; Ghassemian, M.; Villa, E.; Pogliano, J.; Corbett, K. D.
10.1101/2023.05.18.541317 — biochemistry — Posted on 2023-05-18
1813 The nuclear receptor Nr2f6 represses skeletal muscle oxidative metabolism and force production.
Guimaraes, D. S. P. S. F.; Barrios, N. M. F.; de Oliveira, A. G.; Rizo-Roca, D.; Jollet, M.; Smith, J. A. B.; Araujo, T. R.; da Cruz, M. V.; Vieira, A. S.; Hirabara, S. M.; Marconato, E.; Krook, A.; Zierath, J. R.; Silveira, L. d. R.
10.1101/2023.05.17.540900 — biochemistry — Posted on 2023-05-18
1814 Covalent Targeting of Glutamate Cysteine Ligase to Inhibit Glutathione Synthesis
Zhang, L.; Tang, M.; Tao, X.; Shao, Q.; Thomas, V.; Shimizu, S.; Kasano, M.; Ishikawa, Y.; Inukai, T.; Nomura, D. K.
10.1101/2023.05.18.541312 — biochemistry — Posted on 2023-05-18
1815 Examining intra-host genetic variation of RSV by short read high-throughput sequencing
Henke, D. M.; Piedra, F.-A.; Avadhanula, V.; doddapaneni, h. v.; muzny, d. m.; Menon, V.; Hoffman, K.; Ross, M. C.; Javornik Cregeen, S. J.; Metcalf, G.; Gibbs, R. A.; Petrosino, J. F.; Piedra, P.
10.1101/2023.05.17.541198 — genomics — Posted on 2023-05-18
1816 NAC61 regulates late- and post-ripening associated processes in grapes involving a NAC60-dependent regulatory network
Foresti, C.; Orduna, L.; Matus, J. T.; Vandelle, E. G. G.; Danzi, D.; Bellon, O.; Tornielli, G.; Amato, A.; Zenoni, S.
10.1101/2023.05.17.541132 — genetics — Posted on 2023-05-18
1817 Longevity-associated SMAD3 non-coding centenarian variant impairs a cell-type specific enhancer to reduce inflammation
Yang, J.; Tare, A.; Zhang, L.; Kim, S.; Ryu, S.; Guo, Q.; Zhu, Y.; Wang, X.; Wang, X.; Hudgins, A. D.; Guan, D.; Jin, C.; Chang, H.-K.; Atzmon, G.; Milman, S.; Barzilai, N.; Vijg, J.; Niedernhofer, L.; Robbins, P. D.; Suh, Y.
10.1101/2023.05.17.540984 — genetics — Posted on 2023-05-18
1819 Primary production dynamics during the decline phase of the North Atlantic annual spring bloom
Meyer, M. G.; Brzezinski, M.; Cohn, M. R.; Kramer, S. J.; Paul, N.; Sharpe, G. C.; Niebergall, A. K.; Gifford, S. M.; Cassar, N.; Marchetti, A.
10.1101/2023.05.18.541304 — ecology — Posted on 2023-05-18
1820 Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier
Thomas, J. R.; Frye, W. J. E.; Robey, R. W.; Warner, A. C.; Butcher, D.; Matta, J. L.; Morgan, T. C.; Edmondson, E. F.; Gottesman, M. M.
10.1101/2023.05.18.539313 — cell biology — Posted on 2023-05-18
1821 Rapid, efficient auxin-inducible protein degradation in Candida pathogens
Milholland, K. L.; Gregor, J. B.; Hoda, S.; Piriz-Antunez, S.; Duenas-Santero, E.; Vu, B. G.; Patel, K. P.; Moye-Rowley, W. S.; Vazguez de Aldana, C. R.; Correa-Bordes, J.; Briggs, S. D.; Hall, M. C.
10.1101/2023.05.17.541235 — molecular biology — Posted on 2023-05-18
1822 A Recombinant Antibody For Tracking Murine Gammaherpesvirus 68 Uracil DNA Glycosylase Expression.
Mu, Y.; Plummer, J. B.; Zelazowska, M. A.; Paul, S.; Dong, Q.; Chen, Z.; Krug, L. T.; McBride, K. M.
10.1101/2023.05.17.541089 — molecular biology — Posted on 2023-05-18
1825 Heavy Metal Pollution From a Major Earthquake and Tsunami in Chile Is Associated With Geographic Divergence of Clinical Isolates of Methicillin-Resistant Staphylococcus aureus in Latin America
Martinez, J. R.; Alcalde-Rico, M.; Jara-Videla, E.; Rios, R.; Moustafa, A. M.; Hanson, B.; Rivas, L.; Carvajal, L. P.; Rincon, S.; Diaz, L.; Reyes, J.; Quesille-Villalobos, A.; Riquelme-Neira, R.; Undurraga, E. A.; Olivares-Pacheco, J.; Garcia, P.; Araos, R.; Planet, P. J.; Arias, C. A.; Munita, J. M.
10.1101/2023.05.18.541300 — microbiology — Posted on 2023-05-18
1828 Functional and genetic adaptations contributing to Enterococcus faecalis persistence in the female urinary tract
Sharon, B. M.; Arute, A. P.; Nguyen, A.; Tiwari, S.; Bonthu, S. S. R.; Hulyalkar, N. V.; Neugent, M. L.; Araya, D. P.; Dillon, N. A.; Zimmern, P. E.; Palmer, K. L.; De Nisco, N. J.
10.1101/2023.05.18.541374 — microbiology — Posted on 2023-05-18
1829 PenTag, a Versatile Platform for Covalent Bioconjugation, Purification, and Tagging of Proteins Towards the Development of Novel Biohybrid Material Systems
Mohsenin, H.; Pacheco, J.; Kemmer, S.; Wagner, H.; Hoefflin, N.; Bergmann, T.; Baumann, T.; Ripp, A.; Jork, N.; Jessen, H. J.; Koehn, M.; Weber, W.
10.1101/2023.05.18.541264 — synthetic biology — Posted on 2023-05-18
1830 Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2
Li, H. Z.; Pike, A. C. W.; Chi, G.; Hansen, J. S.; Lee, S. G.; Rodstrom, K. E. J.; Bushell, S. R.; Speedman, D.; Evans, A.; Wang, D.; He, D.; Shrestha, L.; Nasrallah, C.; Burgess-Brown, N. A.; Dafforn, T. R.; Carpenter, E. P.; Sauer, D. B.
10.1101/2023.05.17.541173 — biophysics — Posted on 2023-05-18
1831 p300 Is an Obligate Integrator of Combinatorial Transcription Factor Inputs
Ferrie, J. J.; Karr, J. P.; Graham, T. G.; Dailey, G. M.; Zhang, G.; Tjian, R.; Darzacq, X.
10.1101/2023.05.18.541220 — biophysics — Posted on 2023-05-18
1832 Evolution towards simplicity in bacterial small heat shock protein system
Karas, P.; Kochanowicz, K.; Pitek, M.; Domanski, P.; Obuchowski, I.; Tomiczek, B.; Liberek, K.
10.1101/2023.05.18.541272 — biochemistry — Posted on 2023-05-18
1835 Pan-transcriptome reveals a large accessory genome contribution to gene expression variation in yeast
Caudal, E.; Loegler, V.; Dutreux, F.; Vakirlis, N.; Teyssonniere, E.; Caradec, C.; Friedrich, A.; HOU, J.; Schacherer, J.
10.1101/2023.05.17.541122 — genomics — Posted on 2023-05-18
1836 The FIGNL1-FIRRM complex is required to complete meiotic recombination in the mouse and prevents massive DNA damage-independent RAD51 and DMC1 loading
Zainu, A.; Dupaigne, P.; Bouchouika, S.; Cau, J.; Clement, J. A. J.; Auffret, P.; Ropars, V.; Charbonnier, J.-B.; de Massy, B.; Kumar, R.; Baudat, F.
10.1101/2023.05.17.541096 — genetics — Posted on 2023-05-18
1839 Rotten to the core - a neurofunctional signature of subjective core disgust generalizes to socio-moral contexts
Gan, X.; Zhou, F.; Xu, T.; Liu, X.; Zhang, R.; Zheng, Z.; Yang, X.; Zhou, X.; Yu, F.; Li, J.; Cui, R.; Wang, L.; Yuan, J.; Yao, D.; Becker, B.
10.1101/2023.05.18.541259 — neuroscience — Posted on 2023-05-18
1840 Dual-topology of collagen XV and tenascin C acts in concert to guide and shape developing motor axons
Nemoz-Billet, L.; Balland, M.; Gilquin, L.; Gillet, B.; Stevant, I.; Guillon, E.; Hughes, S.; Carpentier, G.; Vaganay, E.; Gonzalez-Melo, M.-J.; Koch, M.; Ghavi-Helm, Y.; Ruggiero, F.; Bretaud, S.
10.1101/2023.05.18.541309 — developmental biology — Posted on 2023-05-18
1846 Leveraging longitudinal diffusion MRI data to quantify differences in white matter microstructural decline in normal and abnormal aging
Archer, D. B.; Schilling, K.; Shashikumar, N.; Jasodanand, V.; Moore, E.; Pechman, K.; Bilgel, M.; Beason-Held, L.; An, Y.; Shafer, A.; Ferrucci, L.; Risacher, S. L.; Gifford, K.; Landman, B.; Landman, B. A.; Jefferson, A.; Saykin, A. J.; Resnick, S. M.; Hohman, T.; Alzheimer's Disease Neuroimaging Initiative,
10.1101/2023.05.17.541182 — neuroscience — Posted on 2023-05-18
1850 Infant attachment behaviors reflect the parenting style of individual caregiver in common marmosets
Yano-Nashimoto, S.; Truzzi, A.; Shinozuka, K.; Murayama, A.; Kurachi, T.; Moriya-Ito, K.; Tokuno, H.; Miyazawa, E.; Esposito, G.; Okano, H.; Nakamura, K.; Saito, A.; Kuroda, K. O.
10.1101/2023.05.18.541258 — animal behavior and cognition — Posted on 2023-05-18
1851 VirB, a key transcriptional regulator of Shigella virulence, requires a CTP ligand for its regulatory activities
Gerson, T. M.; Ott, A. M.; Karney, M. M.; Socea, J. N.; Ginete, D. R.; Iyer, L. M.; Aravind, L.; Gary, R. K.; Wing, H. J.
10.1101/2023.05.16.541010 — microbiology — Posted on 2023-05-18
1854 Human Herpesvirus 8 ORF57 protein is able to reduce TDP-43 pathology: Network analysis Identifies Interacting Pathways
Webber, C. J.; Murphy, C. N.; Rondon-Ortiz, A. N.; van der Spek, S. J.; Kelly, E. X.; Lampl, N. M.; Chiesa, G.; Khalil, A. S.; Emili, A.; Wolozin, B.
10.1101/2023.05.18.540717 — neuroscience — Posted on 2023-05-18
1860 Cbl and Cbl-b Ubiquitin Ligases are Essential for Intestinal Epithelial Stem Cell Maintenance
Zutshi, N.; Mohapatra, B. C.; Mondal, P.; An, W.; Goetz, B. T.; Wang, S.; Li, S.; Storck, M. D.; Mercer, D.; Black, A. R.; Thayer, S. P.; Black, J.; Lin, C.; Band, V.; Band, H.
10.1101/2023.05.17.541154 — cell biology — Posted on 2023-05-18
1861 Unraveling cellular complexity with unlimited multiplexed super-resolution imaging
Schueder, F.; Rivera-Molina, F.; Su, M.; Kidd, P.; Rothman, J. E.; Toomre, D.; Bewersdorf, J.
10.1101/2023.05.17.541061 — cell biology — Posted on 2023-05-18
1862 Telocytes are a critical source of Wnts essential for hair follicle regeneration
Canella, M.; Nalick, S.; Corem, N.; Gharbi, A.; Ben-Porath, I.; Shoshkes Carmel, M.
10.1101/2023.05.17.541070 — cell biology — Posted on 2023-05-18
1864 The cholesterol pathway of the Golgi stress response induces cell death and transcription of Golgi-related genes through metabolic dysregulation of phosphatidylinositol-4-phosphate
Sasaki, K.; Adachi, T.; Morishita, F.; Toide, M.; Watanabe, Y.; Sakurai, H. T.; Wakabayashi, S.; Kusumi, S.; Yamaji, T.; Sakurai, K.; Koga, D.; Hanada, K.; Yohda, M.; Yoshida, H.
10.1101/2023.05.18.541279 — cell biology — Posted on 2023-05-18
1869 An integrative multi-omics approach to draft gene regulatory networks at a cell type resolution
Voronov, D.; Paganos, P.; Magri, M. S.; Cuomo, C.; Maeso, I.; Gomez-Skarmeta, J. L.; Arnone, M. I.
10.1101/2023.05.12.540495 — developmental biology — Posted on 2023-05-18
1870 Rme-6 integrates EGFR trafficking and signalling to regulate ERK1/2 signalosome dynamics
Smythe, E.; Alshahrani, F.; Zhu, Z.; Ferreira, F.; McComb, A.; Maib, H.; Pruzina, S.; Robinson, D.; Murray, D. H.
10.1101/2023.05.05.539436 — cell biology — Posted on 2023-05-18
1871 PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
Chessa, T. A. M.; Jung, P.; Suire, S.; Anwar, A.; Anderson, K. E.; Barneda, D.; Kielkowska, A.; Sadiq, B. A.; Oxley, D.; Felisbino, S.; Spensberger, D.; Segonds-Pichon, A.; Wilson, M.; Walker, S.; Okkenhaug, H.; Cosulich, S.; Hawkins, P. T.; Stephens, L. R.
10.1101/2023.05.18.541123 — cell biology — Posted on 2023-05-18
1872 Myeloid Cell-Derived IL1β Contributes to Pulmonary Vascular Remodeling in Heart Failure with Preserved Ejection Fraction
Agrawal, V.; Kropski, J. A.; Gokey, J. J.; Kobeck, E.; Murphy, M. B.; Murray, K. T.; Fortune, N. L.; Moore, C. S.; Meoli, D. F.; Monahan, K.; Su, Y. R.; Blackwell, T.; Gupta, D. K.; Talati, M. H.; Carrier, E. J.; West, J. D.; Hemnes, A. R.
10.1101/2023.05.18.541302 — cell biology — Posted on 2023-05-18
1874 The NQR complex regulates the immunomodulatory function of Bacteroides thetaiotaomicron
Engelhart, M. J.; Glowacki, R. W.; Till, J. M.; Harding, C. V.; Martens, E. C.; Ahern, P. P.
10.1101/2022.10.21.513251 — microbiology — Posted on 2023-05-18
1875 Neural effects of TMS trains on the human prefrontal cortex
Ross, J. M.; Cline, C. C.; Sarkar, M.; Truong, J.; Keller, C. J.
10.1101/2023.01.30.526374 — neuroscience — Posted on 2023-05-18
1877 Repair oligodendrocytes demyelinating and disintegrating damaged axons after injury
Nocera, G.; Vaquie, A.; Hertzog, N.; Steil, K.; Canon Duque, S. L.; Miedema, J. M.; Bagin, C.; Tevosian, M.; Lutz, B.; Sharifi-Aghili, A.; Hegner, K.; Vollmer, D.; Bang, S.; Lee, S.-R.; Jeon, N. L.; Keyse, S. M.; Raigon Lopez, S.; Jacob, C.
10.1101/2023.05.18.541273 — neuroscience — Posted on 2023-05-18
1881 Limited oxygen availability in standard cell culture alters metabolism and function in terminally-differentiated cells
Tan, J.; Virtue, S.; Norris, D. M.; Conway, O. J.; Yang, M.; Gribben, C.; Lutgu, F.; Krycer, J. R.; Mills, R. J.; Kamzolas, I.; Pereira, C.; Dale, M.; Shun-Shion, A. S.; Baird, H. J.; Horscroft, J. A.; Sowton, A. P.; Ma, M.; Carobbio, S.; Petsalaki, E.; Murray, A. J.; Gershlick, D. C.; Hudson, J. E.; Vallier, L.; Fisher-Wellman, K. H.; Frezza, C.; Vidal-Puig, A.; Fazakerley, D. J.
10.1101/2022.11.29.516437 — cell biology — Posted on 2023-05-18
1884 Reproducibility of in-vivo electrophysiological measurements in mice
The International Brain Laboratory, ; Banga, K.; Benson, J.; Bhagat, J.; Biderman, D.; Birman, D.; Bonacchi, N.; Bruijns, S. A.; Campbell, R. A.; Carandini, M.; Chapuis, G. A.; Churchland, A. K.; Davatolhagh, M. F.; Lee, H. D.; Faulkner, M.; Gercek, B.; Hu, F.; Huntenburg, J. M.; Hurwitz, C.; Khanal, A.; Krasniak, C.; Meijer, G. T.; Miska, N. J.; Mohammadi, Z.; Noel, J.-P.; Paninski, L.; Pan-Vazquez, A.; Roth, N.; Schartner, M.; Socha, K.; Steinmetz, N. A.; Svoboda, K.; Taheri, M.; Urai, A. E.; Wells, M.; West, S. J.; Whiteway, M. R.; Winter, O.; Witten, I. B.
10.1101/2022.05.09.491042 — neuroscience — Posted on 2023-05-18
1885 Single nuclei transcriptomics of human and monkey striatum implicates DNA damage, neuroinflammation, and neurodegeneration signaling in opioid use disorder
Phan, B. N.; Ray, M. H.; Xue, X.; Fenster, R. J.; Kohut, S. J.; Bergman, J.; Haber, S. N.; Mccullough, K. M.; Kuppe-Fish, M. K.; Glausier, J. R.; Su, Q.; Tipton, A. E.; Lewis, D. A.; Freyberg, Z.; Tseng, G. C.; Ressler, K. J.; Russek, S. J.; Alekseyev, Y.; Seney, M. L.; Pfenning, A. R.; Logan, R. W.
10.1101/2023.05.17.541145 — neuroscience — Posted on 2023-05-18
1886 Tractable and Expressive Generative Models of Genetic Variation Data
Dang, M.; Liu, A.; Wei, X.; Sankararaman, S.; Van den Broeck, G.
10.1101/2023.05.16.541036 — genetics — Posted on 2023-05-18
1889 iFlpMosaics: A method for the ratiometric induction and high-throughput comparative analysis of mutant and wildtype cells
Garcia-Gonzalez, I.; Gambera, S.; Regano, A.; Rocha, S. F.; Garcia-Ortega, L.; Lytvyn, M.; Sanchez-Munoz, M. S.; Garcia-Cabero, A.; Zagorac, I.; Luo, W.; Fernandez-Chacon, M.; Casquero-Garcia, V.; Lunella, F. F.; Benedito, R.
10.1101/2023.05.09.540000 — cell biology — Posted on 2023-05-18
1890 Global genomic analysis reveals the genetic origin and secondary invasion of fall armyworm in the Eastern hemisphere
Zhang, L.; Li, Z.; Peng, Y.; Liang, X.; Wilson, K.; Chipabika, G.; Karangwa, P.; Uzayisenga, B.; Mensah, B. A.; Kachigamba, D. L.; Xiao, Y.
10.1101/2022.09.16.508260 — molecular biology — Posted on 2023-05-18
1895 Recovery of a learned behavior despite partial restoration of neuronal dynamics after chronic inactivation of inhibitory neurons
Torok, Z.; Luebbert, L.; Feldman, J.; Duffy, A.; Nevue, A.; Wongso, S.; Mello, C.; Fairhall, A.; Pachter, L.; Gonzalez, W. G.; Lois, C.
10.1101/2023.05.17.541057 — neuroscience — Posted on 2023-05-18
1896 Chronic activation of the aryl hydrocarbon receptor in muscle exacerbates ischemic pathology in chronic kidney disease
Balestrieri, N.; Palzkill, V.; Pass, C. G.; Tan, J.; Salyers, Z. R.; Moparthy, C.; Murillo, A.; Kim, K.; Thome, T.; Yang, Q.; O'Malley, K.; Berceli, S. A.; Yue, F.; Scali, S. T.; Ferreira, L. F.; Ryan, T. E.
10.1101/2023.05.16.541060 — physiology — Posted on 2023-05-18
1897 Single-cell spatial atlas of tertiary lymphoid structures in ovarian cancer
Sarkkinen, J.; Junquera Mencia, A.; Anttila, E.; Szabo, A.; Perez, F.; Launonen, I.-M.; Laury, A.; Casado, J.; Kekalainen, E.; Farkkila, A.
10.1101/2023.05.16.540946 — cancer biology — Posted on 2023-05-18
1903 A central helical hairpin in SPD-5 enables centrosome strength and assembly
Rios, M. U.; Ryder, B. D.; Familiari, N.; Joachimiak, Łukasz A.; Woodruff, J. B.
10.1101/2023.05.16.540868 — cell biology — Posted on 2023-05-18
1904 Host-parasite interactions in perpetual darkness: macroparasite diversity in the cavefish Astyanax mexicanus
Santacruz, A.; Hernandez-Mena, D.; Miranda-Gamboa, R.; Perez-Ponce de Leon, G.; Ornelas-Garcla, C. P.
10.1101/2023.05.16.540976 — zoology — Posted on 2023-05-18
1907 Simple droplet microfluidics platform for drug screening on cancer spheroids
Parent, C.; Raj Melayil, K.; Zhou, Y.; Aubert, V.; Surdez, D.; Delattre, O.; Wilhelm, C.; Viovy, J.-L.
10.1101/2023.05.16.540960 — cancer biology — Posted on 2023-05-18
1911 Deep learning and host variable embedding augment microbiome-based simultaneous detection of multiple diseases
Wu, S.; Li, Z.; Chen, Y.; Zhang, M.; Sun, Y.; Xing, J.; Zhao, F.; Huang, S.; Knight, R.; Su, X.
10.1101/2023.05.16.541058 — bioinformatics — Posted on 2023-05-18
1913 CENTRE: A gradient boosting algorithm for Cell-type-specific ENhancer-Target pREdiction
Rapakoulia, T.; Lopez, S. R. d. V.; Omgba, P. A.; Laupert, V.; Ulitsky, I.; Vingron, M.
10.1101/2023.05.16.541035 — bioinformatics — Posted on 2023-05-18
1914 Investigating mitochondrial gene expression patterns in Drosophila melanogaster using network analysis to understand aging mechanisms
Mangoni, M.; Petrizzelli, F.; Liorni, N.; Bianco, S. D.; Biagini, T.; Napoli, A.; Adinolfi, M.; Guzzi, P. H.; Novelli, A.; Caputo, V.; Mazza, T.
10.1101/2023.05.16.540914 — bioinformatics — Posted on 2023-05-18
1915 RealSeq2: a software integrated with UMI identification, error correction, and methylation modifications storing
Wang, K.; Song, M.; Li, M.; Cui, T.; Liu, Z.; Yu, E.; Fang, H.; Gao, X.; Xia, X.; Wang, J.; Guan, Y.; Liu, T.; Yi, X.
10.1101/2023.05.16.539668 — bioinformatics — Posted on 2023-05-18
1916 Visible-Light Optical Coherence Tomography Fibergraphy of the Tree Shrew Retinal Ganglion Cell Axon Bundles
Miller, D.; Grannonico, M.; Liu, M.; Savier, E.; McHaney, K.; Erisir, A.; Netland, P.; Liu, X.; Zhang, H. F.
10.1101/2023.05.16.541062 — bioengineering — Posted on 2023-05-18
1917 Novel Curcuphenol Analogues Possess Anti-Metastatic Biologic Activity
Ellis, S. L. S.; Nohara, L. L.; Dada, S.; Saranchova, I.; Munro, L.; Choi, K. B.; Garrovillas, E.; Pfeifer, C. G.; Williams, D. E.; Cheng, P.; Andersen, R. J.; Jefferies, W.
10.1101/2023.05.15.540833 — biochemistry — Posted on 2023-05-18
1918 A chromosome-level reference genome for the common octopus, Octopus vulgaris (Cuvier, 1797)
Destanovic, D.; Schultz, D. T.; Styfhals, R.; Cruz, F.; Gomez-Garrido, J.; Gut, M.; Gut, I.; Fiorito, G.; Simakov, O.; Alioto, T. S.; Ponte, G.; Seuntjens, E.
10.1101/2023.05.16.540928 — genomics — Posted on 2023-05-18
1920 Novel and improved Caenorhabditis briggsae gene models generated by community curation
Moya, N. D.; Stevens, L.; Miller, I. R.; Galindo, J. L.; Bardas, A. D.; Yeo, C.; Rozenich, A. J.; Xu, M.; Koh, E. S. H.; Andersen, E. C.
10.1101/2023.05.16.541014 — genomics — Posted on 2023-05-18
1921 What can Ribo-seq and proteomics tell us about the non-canonical proteome?
Prensner, J. R.; Abelin, J. G.; Kok, L. W.; Clauser, K. R.; Mudge, J. M.; Ruiz-Orera, J.; Bassani-Sternberg, M.; Deutsch, E. W.; van Heesch, S.
10.1101/2023.05.16.541049 — genomics — Posted on 2023-05-18
1922 CRISPR-based diagnostics detects invasive insect pests
Shashank, P. R.; Parker, B. M.; Rananaware, s.; Plotkin, D.; Couch, C.; Yang, L. G.; Nguyen, L. T.; Prasannakumar, N. R.; Braswell, W. E.; Jain, P. K.; Kawahara, A. Y.
10.1101/2023.05.16.541004 — genetics — Posted on 2023-05-18
1926 Adipocytes regulate fibroblast function, and their loss contributes to fibroblast dysfunction in inflammatory diseases
Faust, H.; Cheng, T.-Y.; Korsunsky, I.; Watts, G. F. M.; Gal-Oz, S. T.; Trim, W.; Kongthong, K.; Jonsson, A. H.; Simmons, D. P.; Zhang, F.; Padera, R.; Chubinskaya, S.; Accelerating Medicines Partnership Program, ; Wei, K.; Raychaudhuri, S.; Lynch, L.; Moody, B.; Brenner, M. B.
10.1101/2023.05.16.540975 — cell biology — Posted on 2023-05-18
1927 New permanent stem cell niche for development and regeneration in a chordate
Vanni, V.; Caicci, F.; Peronato, A.; Martello, G.; Asnicar, D.; Gasparini, F.; Ballarin, L.; Manni, L.
10.1101/2023.05.15.540819 — cell biology — Posted on 2023-05-18
1928 Multivalent coiled-coil interactions enable full-scale centrosome assembly and strength
Rios, M. U.; Bagnucka, M. A.; Ryder, B. D.; Gomes, B. F.; Familiari, N.; Yaguchi, K.; Amato, M.; Joachimiak, Łukasz A.; Woodruff, J. B.
10.1101/2023.05.15.540834 — cell biology — Posted on 2023-05-18
1929 T-FINDER: A highly sensitive, pan-HLA platform for functional T cell receptor and ligand discovery
Schmid, T.; Cetin, M.; Pinamonti, V.; Fuentes, A. M.; Kromer, K.; Lerner, T.; Zhang, J.; Boschert, T.; Herzig, Y.; Ehlert, C.; Fisch, L.; Dragan, V.; Kouwenhoven, A.; Van Schoubroeck, B.; Wils, H.; Van Hove, C.; Platten, M.; Green, E. W.; Stevenaert, F.; Felix, N.; Lindner, J. M.
10.1101/2023.05.16.540992 — immunology — Posted on 2023-05-18
1930 Indirect Correlative Light and Electron Microscopy (iCLEM): A Novel Pipeline for Multiscale Quantification of Structure from Molecules to Organs
Struckman, H. L.; Moise, N.; Vanslembrouck, B.; Rothacker, N.; Chen, Z.; van Hengel, J.; Weinberg, S. H.; Veeraraghavan, R.
10.1101/2023.05.15.540853 — systems biology — Posted on 2023-05-18
1932 Controlled expression of avian migratory fattening influences innate immune responses
Tobolka, M.; Zielinska, Z.; Fusani, L.; Huber, N.; Maggini, I.; Pola, G.; Marasco, V.
10.1101/2023.05.15.540777 — physiology — Posted on 2023-05-18
1934 Optimization of 3-Cyano-7-cyclopropylamino-pyrazolopyrimidines Toward the Development of an In Vivo Chemical Probe for CSNK2
Yang, X.; Ong, H. W.; Dickmander, R. J.; Smith, J. L.; Brown, J. W.; Tao, W.; Chang, E.; Moorman, N. J.; Axtman, A. D.; Willson, T. M.
10.1101/2023.05.15.540828 — pharmacology and toxicology — Posted on 2023-05-18
1936 Novel psilocin prodrugs with altered pharmacological properties as candidate therapies for treatment-resistant anxiety disorders
Raithatha, S. A.; Hagel, J. M.; Matinkhoo, K.; Yu, L.; Press, D.; Cook, S. G.; Sharma, G.; Dhananjaya, D.; Jensen, G.; Lee, J. B.; Cai, C.; Gallant, J.; Bains, J. S.; Tucker, J. E.; Facchini, P. J.
10.1101/2023.05.16.540994 — pharmacology and toxicology — Posted on 2023-05-18
1937 ERG-driven prostate cancer emerges from basal-luminal hybrid cells
Feng, W.; Ladewig, E.; Salsabeel, N.; Zhao, H.; Lee, Y. S.; Gopalan, A.; Luo, H.; Kang, W.; Fan, N.; Rosiek, E.; Masilionis, I.; Chaligne, R.; De Stanchina, E.; Chen, Y.; Carver, B. S.; Leslie, C. S.; Sawyers, C.
10.1101/2023.05.15.540839 — cancer biology — Posted on 2023-05-18
1939 Multiomic Single Cell Sequencing Identifies Stemlike Nature of Mixed Phenotype Acute Leukemia and Provides Novel Risk Stratification
Peretz, C. A. C.; Kennedy, V. E.; Walia, A.; Delley, C. L.; Koh, A.; Tran, E.; Clark, I.; Hayford, C. E.; D'Amato, C.; Xue, Y.; Fontanez, K. M.; Roy, R.; Logan, A. C.; Perl, A. E.; Abate, A.; Olshen, A.; Smith, C. C.
10.1101/2023.05.15.540305 — cancer biology — Posted on 2023-05-18
1940 Patient-derived xenografts and single-cell sequencing identifies three subtypes of tumor-reactive lymphocytes in uveal melanoma metastases
Karlsson, J. W.; Sah, V. R.; Olofsson Bagge, R.; Iqba, M.; Alsen, S.; Stenqvist, S.; Saxena, A.; Ny, L.; Nilsson, L.; Nilsson, J. A.
10.1101/2023.05.16.540908 — cancer biology — Posted on 2023-05-18
1942 Overcoming the speed limit of four-way DNA branch migration with bulges in toeholds
Smith, F.; Sengar, A.; Stan, G.-B. V.; Ouldridge, T. E.; Stevens, M.; Goertz, J.; Bae, W.
10.1101/2023.05.15.540824 — biophysics — Posted on 2023-05-18
1943 Deciphering the interplay between biology and physics: finite element method-implemented vertex organoid model raises the challenge
LAUSSU, J.; Michel, D.; Magne, L.; Segonds, S.; Marguet, S.; Hamel, D.; Quaranta-Nicaise, M.; Barreau, F.; Mas, E.; VELAY, V.; BUGARIN, F.; FERRAND, A.
10.1101/2023.05.15.540870 — biophysics — Posted on 2023-05-18
1955 A common gene signature of the right ventricle in failing rat and human hearts
Jurida, L.; Werner, S.; Knapp, F.; Niemann, B.; Li, L.; Gruen, D.; Wirth, S.; Weber, A.; Beuerlein, K.; Liebetrau, C.; Wiedenroth, C. B.; Guth, S.; Kojonazarov, B.; Jafari, L.; Weissmann, N.; Guenther, S.; Braun, T.; Rohrbach, S.; Kracht, M.
10.1101/2023.05.16.540913 — genomics — Posted on 2023-05-18
1958 Interruption of the Intratumor CD8:Treg Crosstalk Improves the Efficacy of PD-1 Immunotherapy
Geels, S. N.; Moshensky, A.; Sousa, R. S.; Walker, B. L.; Singh, R.; Gutierrez, G.; Hwang, M.; Mempel, T. R.; Nie, Q.; Othy, S.; Marangoni, F.
10.1101/2023.05.15.540889 — immunology — Posted on 2023-05-18
1962 Repetitive Sulfur Dioxide Exposure in Mice Models Post-Deployment Respiratory Syndrome
Gutor, S. S.; Salinas, R. I.; Nichols, D. S.; Bazzano, J. M. R.; Han, W.; Gokey, J. J.; Vasiukov, G.; West, J. D.; Newcomb, D. C.; Dikalova, A. E.; Richmond, B. W.; Dikalov, S. I.; Blackwell, T. S.; Polosukhin, V. V.
10.1101/2023.05.15.540867 — pathology — Posted on 2023-05-18
1963 Enteric pharmacokinetics of monomeric and multimeric camelid nanobody single-domain antibodies
Debatis, M.; Danz, H.; Tremblay, J. M.; Gaspie, K.; Kudej, R.; Vigdorovich, V.; Sather, N.; Jaskiewicz, J.; Tzipori, S.; Shoemaker, C. B.
10.1101/2023.05.15.540785 — bioengineering — Posted on 2023-05-18
1964 Tumor Cytokine-Induced Hepatic Gluconeogenesis Contributes to Cancer Cachexia: Insights from Full Body Single Nuclei Sequencing
Liu, Y.; Dantas, E.; Ferrer, M.; Liu, Y.; Comjean, A.; Davidson, E. E.; Hu, Y.; Goncalves, M. D.; Janowitz, T.; Perrimon, N.
10.1101/2023.05.15.540823 — genetics — Posted on 2023-05-18
1967 Cutin-Derived Oligomers Act as Damage-Associated Molecular Patterns in Arabidopsis thaliana
Moreira, C. J.; Escorcio, R.; Bento, A.; Bjornson, M.; Tome, A. S.; Martins, C.; Fanuel, M.; Martins, I.; Bakan, B.; Zipfel, C.; Silva Pereira, C.
10.1101/2023.05.16.540997 — plant biology — Posted on 2023-05-18
1968 Concurrent measurement of O2 and isoprene production during photosynthesis: pros, cons, and metabolic implications
Som, S.; Gallo, L. B.; Sunder, A.; Demus, J.; Domingues, T. F.; Wistrom, C. M.; Gu, L.; Tcherkez, G. G. B.; Jardine, K.
10.1101/2023.05.15.540825 — plant biology — Posted on 2023-05-18
1969 Design of multi-epitope vaccine candidate against Brucella type IV secretion system (T4SS)
Yin, Z.; Li, M.; Niu, C.; Yu, M.; Xie, X.; Haimiti, G.; Guo, W.; Shi, J.; He, Y.; Ding, J.; Zhang, F.
10.1101/2023.05.16.540940 — bioinformatics — Posted on 2023-05-18
1970 Comparative analysis of drug-like EP300/CREBBP acetyltransferase inhibitors
Crawford, M. C.; Tripu, D. R.; Barritt, S. A.; Jing, Y.; Gallimore, D.; Kales, S. C.; Bhanu, N. V.; Xiong, Y.; Fang, Y.; Butler, K. A. T.; LeClair, C. A.; Coussens, N. P.; Simeonov, A.; Garcia, B. A.; Dibble, C. C.; Meier, J. L.
10.1101/2023.05.15.540887 — biochemistry — Posted on 2023-05-18
1972 Divergent host innate immune response to the smooth-to-rough M. abscessus adaptation to chronic infection
Malcolm, K. C.; Wheeler, E. A.; Lenhart-Pendergrass, P. M.; Rrysavy, N. M.; Poch, K. R.; Caceres, S. M.; Calhoun, K. M.; Serban, K. A.; Nick, J. A.
10.1101/2023.05.15.540822 — immunology — Posted on 2023-05-18
1973 Benchmarking long-read RNA-sequencing analysis tools using in silico mixtures
Dong, X.; Du, M. R. M.; Gouil, Q.; Tian, L.; Jabbari, J. S.; Bowden, R.; Baldoni, P. L.; Chen, Y.; Smyth, G. K.; Amarasinghe, S. L.; Law, C. W.; Ritchie, M. E.
10.1101/2022.07.22.501076 — bioinformatics — Posted on 2023-05-18
1975 Inference of cell type-specific gene regulatory networks on cell lineages from single cell omic datasets
Zhang, S.; Pyne, S.; Pietrzak, S.; Halberg, S.; McCalla, S. G.; Siahpirani, A. F.; Sridharan, R.; Roy, S.
10.1101/2022.07.25.501350 — bioinformatics — Posted on 2023-05-18
1978 Elucidating polymorphs of crystal structures with intensity-based hierarchical clustering analysis on multiple diffraction datasets
Matsuura, H.; Sakai, N.; Toma-Fukai, S.; Muraki, N.; Hayama, K.; Kamikubo, H.; Aono, S.; Kawano, Y.; Yamamoto, M.; Hirata, K.
10.1101/2022.09.13.507775 — molecular biology — Posted on 2023-05-18
1979 Spatial proteomics in neurons at single-protein resolution
Unterauer, E. M.; Boushehri, S. S.; Jevdokimenko, K.; Masullo, L. A.; Ganji, M.; Sograte-Idrissi, S.; Kowalewski, R.; Strauss, S.; Reinhardt, S. C.; Perovic, A.; Marr, C.; Opazo, F.; Fornasiero, E. F.; Jungmann, R.
10.1101/2023.05.17.541210 — neuroscience — Posted on 2023-05-18
1980 Folding of the cerebellar cortex is clade-specific in form, but universal in degree
York, A. R.; Sherwood, C. C.; Manger, P. R.; Kaas, J. H.; Mota, B.; Herculano-Houzel, S.
10.1101/2023.05.17.541232 — neuroscience — Posted on 2023-05-18
1982 Recovery of a learned behavior despite partial restoration of neuronal dynamics after chronic inactivation of inhibitory neurons
Torok, Z.; Luebbert, L.; Feldman, J.; Duffy, A.; Nevue, A.; Wongso, S.; Mello, C.; Fairhall, A.; Pachter, L.; Gonzalez, W.; Lois, C.
10.1101/2023.05.17.541057 — neuroscience — Posted on 2023-05-18
1985 Direct inference and control of genetic population structure from RNA sequencing data
Fachrul, M.; Karkey, A.; Shakya, M.; Judd, L. M.; Harshegyi, T.; Sim, K. S.; Tonks, S.; Dongol, S.; Shrestha, R.; Salim, A.; STRATAA study group, ; Baker, S.; Pollard, A. J.; Khor, C. C.; Dolecek, C.; Basnyat, B.; Dunstan, S. J.; Holt, K. E.; Inouye, M.
10.1101/2022.09.16.508259 — bioinformatics — Posted on 2023-05-18
1989 Epigenome Editing Durability Varies Widely Across Cardiovascular Disease Target Genes
Whittaker, M. N.; Testa, L. C.; Quigley, A.; Jindal, I.; Cortez-Alvarado, S.; Qu, P.; Yang, Y.; Alameh, M.-G.; Musunuru, K.; Wang, X.
10.1101/2023.05.17.541156 — genomics — Posted on 2023-05-17
1990 Single-cycle SARS-CoV-2 vaccine elicits high protection and sterilizing immunity in hamsters
Lett, M. J.; Otte, F.; Hauser, D.; Schoen, J.; Kipfer, E. T.; Hoffmann, D.; Halwe, N. J.; Ulrich, L.; Zhang, Y.; Cmiljanovic, V.; Wylezich, C.; Urda, L.; Lang, C.; Beer, M.; Mittelholzer, C.; Klimkait, T.
10.1101/2023.05.17.541127 — molecular biology — Posted on 2023-05-17
1991 Reorganization of Pancreas Circadian Transcriptome with Aging
Sharma, D.; Wessel, C. R.; Mahdavinia, M.; Preuss, F.; Bishehsari, F.
10.1101/2023.05.17.541196 — molecular biology — Posted on 2023-05-17
1992 Belgian Culex pipiens pipiens are competent vectors for West Nile virus but not Usutu virus
Soto, A.; De Coninck, L.; Devlies, A.-S.; Van De Wiele, C.; Rosas, A. L. R.; Wang, L.; Matthijnssens, J.; Delang, L.
10.1101/2023.05.17.541091 — microbiology — Posted on 2023-05-17
1993 Unraveling human, rodent and snake Kolmioviridae replication to anticipate cross-species transmission
Majzoub, K.; Khalfi, P.; Denis, Z.; Merolla, G.; Chavey, C.; Ursic-Bedoya, J.; Soppa, L.; Szirovicza, L.; Hetzel, U.; Dufourt, J.; Leyrat, C.; Goldmann, N.; Goto, K.; Verrier, E.; Baumert, T. F.; Glebe, D.; Courgnaud, V.; Gregoire, D.; Hepojoki, J.
10.1101/2023.05.17.541162 — microbiology — Posted on 2023-05-17
1995 Sex-dependent improvement in traumatic brain injury outcomes after liposomal delivery of dexamethasone in mice.
Baudo, G.; Flinn, H.; Holcomb, M.; Tiwari, A.; Soriano, S.; Taraballi, F.; Zinger, A.; Godin, B.; Villapol, S.
10.1101/2023.05.16.541045 — neuroscience — Posted on 2023-05-17
1997 Neuropeptide Y signaling regulates recurrent excitation in the auditory midbrain
Silveira, M. A.; Drotos, A. C.; Pirrone, T. M.; Versalle, T. S.; Bock, A.; Roberts, M. T.
10.1101/2023.05.16.540954 — neuroscience — Posted on 2023-05-17
1999 Discovery of Novel Allosteric Sites of SARS-CoV-2 Papain-Like Protease (PLpro)
Al Adem, K.; Ferreira, J. C.; Fadl, S.; Villanueva, A. J.; Alzyoud, L.; Ghattas, M. A.; Rabeh, W. M.
10.1101/2023.05.16.540953 — biochemistry — Posted on 2023-05-17
2003 VirB, a key transcriptional regulator of Shigella virulence, requires a CTP ligand for its regulatory activities
Gerson, T. M.; Ott, A. M.; Karney, M. M.; Socea, J. N.; Ginete, D. R.; Iyer, L. M.; Aravind, L.; Gary, R. K.; Wing, H. J.
10.1101/2023.05.16.541010 — molecular biology — Posted on 2023-05-17
2005 Genomic surveillance of antimicrobial-resistant Escherichia coli in fecal sludge and sewage in Uganda
Gomi, R.; Matsumura, Y.; Yamamoto, M.; Tanaka, M.; Komakech, A. J.; Matsuda, T.; Harada, H.
10.1101/2023.05.17.540885 — microbiology — Posted on 2023-05-17
2008 The Azotobacter vinelandii AlgU Regulon During Vegetative Growth and Encysting Conditions: A Proteomic Approach
Chowdhury-Paul, S.; Martinez-Ortiz, I. C.; Pando-Robles, V.; Moreno, S.; Espin, G.; Merino, E.; Nunez, C.
10.1101/2023.05.17.541114 — microbiology — Posted on 2023-05-17
2010 Spatial transcriptomics reveals molecular dysfunction associated with Lewy pathology
Goralski, T.; Meyerdirk, L.; Breton, L.; Brasseur, L.; Kurgat, K.; DeWeerd, D.; Turner, L.; Becker, K.; Adams, M.; Newhouse, D.; Henderson, M. X.
10.1101/2023.05.17.541144 — neuroscience — Posted on 2023-05-17
2011 RNA- and ATAC-sequencing Reveals a Unique CD83+ Microglial Population Focally Depleted in Parkinson's Disease
Chatila, Z. K.; Yadav, A.; Mares, J.; Flowers, X. E.; Yun, T. D.; Rashid, M.; Talcoff, R.; Pelly, Z.; Zhang, Y.; De Jager, P. L.; Teich, A. F.; Costa, R. M.; Gomez, E. A.; Martins, G. J.; Alcalay, R. N.; Vonsattel, J. P.; Menon, V.; Bradshaw, E. M.; Przedborski, S.
10.1101/2023.05.17.540842 — neuroscience — Posted on 2023-05-17
2015 Identification of Novel Scaffold Proteins for Improved Endogenous Engineering of Extracellular Vesicles
Zheng, W.; Radler, J.; Sork, H.; Niu, Z.; Roudi, S.; Bost, J.; Gorgens, A.; Zhao, Y.; Mamand, D.; Liang, X.; Wiklander, O.; Lehto, T.; Gupta, D.; Nordin, J.; EL Andaloussi, S.
10.1101/2023.05.17.541095 — synthetic biology — Posted on 2023-05-17
2018 Ghost fragment ions in structure and site-specific glycoproteomics analysis
Campos, D.; Girgis, M. A. Y.; Yang, Q.; Zong, G.; Goldman, R.; Wang, L.-X.; Sanda, M.
10.1101/2023.05.17.541150 — biochemistry — Posted on 2023-05-17
2019 mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome
Low, J. K.; Patel, K.; Solomon, P.; Norman, A.; Pachl, P.; Jones, N.; Payne, R. J.; Passioura, T.; Suga, H.; Walport, L. J.; Mackay, J.
10.1101/2023.05.17.541126 — biochemistry — Posted on 2023-05-17
2023 Are circadian amplitudes and periods correlated? A new twist in the story
del Olmo, M.; Schmal, C.; Mizaikoff, C.; Grabe, S.; Gabriel, C.; Kramer, A.; Herzel, H.
10.1101/2023.05.17.541139 — molecular biology — Posted on 2023-05-17
2024 Environmental Persistence and Disinfection of Lassa Virus
Shaffer, M.; Fischer, R.; Gallogly, S.; Ginn, O.; Munster, V.; Bibby, K.
10.1101/2023.05.17.541161 — microbiology — Posted on 2023-05-17
2025 Neo-functionalization in Saccharomyces cerevisiae: A Novel Nrg1-Rtg3 chimeric transcriptional modulator is essential to maintain mitochondrial DNA integrity
Campero-Basaldua, C.; Gonzalez, J.; Garcia-Rodriguez, J.; Ramirez, E.; Hernandez, H.; Aguirre, B.; Torres-Ramirez, N.; Marquez, D.; Sanchez, N. S.; Gomez-Hernandez, N.; Riego-Ruiz, L.; Scazzocchio, C.; Gonzalez, A.
10.1101/2023.05.17.541047 — microbiology — Posted on 2023-05-17
2029 Longitudinal analysis of memory T follicular helper cells and antibody response following CoronaVac vaccination
Zhou, P.; Cao, C.; Ji, T.; Zheng, T.; Dai, Y.; Liu, M.; Jiang, J.; Sun, D.; Bai, Z.; Lu, X.; Gong, F.
10.1101/2023.05.16.541033 — immunology — Posted on 2023-05-17
2033 Modeling and Simulation of Neocortical Micro- and Mesocircuitry. Part II: Physiology and Experimentation
Isbister, J. B.; Ecker, A.; Pokorny, C.; Bolanos-Puchet, S.; Egas Santander, D.; Arnaudon, A.; Awile, O.; Barros-Zulaica, N.; Blanco Alonso, J.; Boci, E.; Chindemi, G.; Courcol, J.-D.; Damart, T.; Delemontex, T.; Dietz, A.; Ficarelli, G.; Gevaert, M.; Herttuainen, J.; Ivaska, G.; Ji, W.; Keller, D.; King, J.; Kumbhar, P.; Lapere, S.; Litvak, P.; Mandge, D.; Muller, E. B.; Pereira, F.; Planas, J.; Ranjan, R.; Reva, M.; Romani, A.; Rössert, C.; Schürmann, F.; Sood, V.; Teska, A.; Tuncel, A.; Van Geit, W.; Wolf, M.; Markram, H.; Ramaswamy, S.; Reimann, M. W.
10.1101/2023.05.17.541168 — neuroscience — Posted on 2023-05-17
2034 Information Geometry of the Retinal Representation Manifold
Ding, X.; Lee, D.; Melander, J. B.; Sivulka, G.; Ganguli, S.; Baccus, S. A.
10.1101/2023.05.17.541206 — neuroscience — Posted on 2023-05-17
2035 Community-based Reconstruction and Simulation of a Full-scale Model of Region CA1 of Rat Hippocampus
Romani, A.; Antonietti, A.; Bella, D.; Budd, J.; Giacalone, E.; Kurban, K.; Saray, S.; Abdellah, M.; Arnaudon, A.; Boci, E.; Colangelo, C.; Courcol, J.-D.; Delemontex, T.; Ecker, A.; Falck, J.; Favreau, C.; Gevaert, M.; Hernando, J. B.; Herttuainen, J.; Ivaska, G.; Kanari, L.; Kaufmann, A.-K.; King, J. G.; Kumbhar, P.; Lange, S.; Lu, H.; Lupascu, C. A.; Migliore, R.; Petitjean, F.; Planas, J.; Rai, P.; Ramaswamy, S.; Reimann, M. W.; Riquelme, J. L.; Guerrero, N. R.; Shi, Y.; Sood, V.; Sy, M. F.; Van Geit, W.; Vanherpe, L.; Freund, T.; Mercer, A.; Muller, E.; Schurmann, F.; Thomson, A. M.; Migl
10.1101/2023.05.17.541167 — neuroscience — Posted on 2023-05-17
2036 Unravelling a novel role for Cannabidivarin in the modulation of subventricular zone postnatal neurogenesis
Lourenco, D. M.; Soares, R.; Santos, S. S.; Mateus, J. M.; Rodrigues, R. S.; Moreira, J. B.; Vaz, S. H.; Sebastiao, A. M.; Sola, S.; Xapelli, S.
10.1101/2023.05.16.540990 — neuroscience — Posted on 2023-05-17
2038 On the results of causal optogenetic engram manipulations
Jou, C.; Hurtado, J. R.; Carrillo-Segura, S.; PARK, E. H.; Fenton, A. A.
10.1101/2023.05.15.540888 — neuroscience — Posted on 2023-05-17
2039 SARS-CoV-2 infection leads to Tau pathological signature in neurons
Di Primio, C.; Quaranta, P.; Mignanelli, M.; Siano, G.; Bimbati, M.; Piazza, C. R.; Spezia, P. G.; Perrera, P.; Basolo, F.; Poma, A. M.; Costa, M.; Pistello, M.; Cattaneo, A.
10.1101/2023.05.17.541098 — neuroscience — Posted on 2023-05-17
2040 Chronic stress triggers seeking of a starvation-like state in anxiety-prone female mice
Kucukdereli, H.; Pottala, T.; Amsalem, O.; Lim, M.; Potgieter, L.; Hasbrouck, A.; Lutas, A.; Andermann, M. L.
10.1101/2023.05.16.541013 — neuroscience — Posted on 2023-05-17
2041 Modular subgraphs in large-scale connectomes underpin spontaneous co-fluctuation "events" in mouse and human brains
Ragone, E.; Tanner, J.; Jo, Y.; Zamani Esfahlani, F.; Faskowitz, J.; Pope, M.; Coletta, L.; Gozzi, A.; Betzel, R.
10.1101/2023.05.17.538593 — neuroscience — Posted on 2023-05-17
2042 Infection-induced epilepsy is caused by increased expression of chondroitin sulfate proteoglycans in hippocampus and amygdala
Patel, D. C.; Swift, N.; Tewari, B. P.; Browning, J. L.; Prim, C.; Chaunsali, L.; Kimbrough, I.; Olsen, M. L.; Sontheimer, H.
10.1101/2023.05.16.541066 — neuroscience — Posted on 2023-05-17
2043 Curiosity as an amplifier of reward-related feedback processing
Rueterbories, T.; Mecklinger, A.; Eschmann, K. C. J.; Crivelli-Decker, J.; Ranganath, C.; Gruber, M. J.
10.1101/2023.05.17.540372 — neuroscience — Posted on 2023-05-17
2045 Extrastriate activity reflects the absence of local retinal input
Urale, P. W. B.; Zhu, L.; Gough, R.; Arnold, D. H.; Schwarzkopf, D. S.
10.1101/2023.05.15.540895 — neuroscience — Posted on 2023-05-17
2046 Xylazine co-self-administration suppresses fentanyl consumption during self-administration and induces a unique sex-specific withdrawal syndrome that is not altered by naloxone in rats
Khatri, S. N.; Sadek, S.; Kendrick, P. T.; Bondy, E. O.; Hong, M.; Pauss, S.; Luo, D.; Prisinzano, T.; Dunn, K. E.; Marusich, J. A.; Beckmann, J.; Hinds, T.; Gipson, C. D.
10.1101/2023.05.17.541158 — animal behavior and cognition — Posted on 2023-05-17
2048 Bayesian hierarchical modeling of size spectra
Wesner, J. S.; Pomeranz, J. P. F.; Junker, J. R.; Gjoni, V.
10.1101/2023.02.14.528491 — ecology — Posted on 2023-05-17
2050 Comparative single-cell analyses identify shared and divergent features of human and mouse kidney development
Kim, S.; Koppitch, K.; Parvez, R. K.; Guo, J.; Achieng, M.; Schnell, J.; Lindstrom, N. O.; McMahon, A. P.
10.1101/2023.05.16.540880 — developmental biology — Posted on 2023-05-17
2051 The cellular basis of feeding-dependent body size plasticity in sea anemones
Garschall, K.; Garcia-Pascual, B.; Pascual-Carreras, E.; Filimonova, D.; Guse, A.; Johnston, I. G.; Steinmetz, P. R. H.
10.1101/2023.05.15.540851 — developmental biology — Posted on 2023-05-17
2053 Apical-driven cell sorting optimised for tissue geometry ensures robust patterning
Moghe, P.; Belousov, R.; Ichikawa, T.; Iwatani, C.; Tsukiyama, T.; Graner, F.; Erzberger, A.; Hiiragi, T.
10.1101/2023.05.16.540918 — developmental biology — Posted on 2023-05-17
2054 The emergence of human gastrulation upon in vitro attachment
De Santis, R.; Rice, E.; Croft, G.; Yang, M.; Rosado-Olivieri, E. A.; Brivanlou, A. H.
10.1101/2023.05.16.541017 — developmental biology — Posted on 2023-05-17
2055 Gap junction-dependent amino acid transfer promotes germ cell growth
Vachias, C.; Tourlonias, C.; Grelee, L.; Gueguen, N.; Renaud, Y.; Richard, G.; Venugopal, P.; Pouchin, P.; Brasset, E.; Mirouse, V.
10.1101/2023.05.15.540837 — developmental biology — Posted on 2023-05-17
2057 A Novel Homeostatic Mechanism Tunes PI(4,5)P2-dependent Signaling at the Plasma Membrane
Wills, R. C.; Doyle, C. P.; Zewe, J. P.; Pacheco, J.; Hansen, S. D.; Hammond, G. R.
10.1101/2022.06.30.498262 — cell biology — Posted on 2023-05-17
2058 The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery
Li, Y.; Wang, F.; Li, X.; Wang, L.; Yang, Z.; You, Z.; Peng, A.
10.1101/2023.02.22.529521 — cell biology — Posted on 2023-05-17
2059 Evidence that ultrafast non-quantal transmission underlies short-latency vestibular evoked potentials.
Pastras, C. J.; Curthoys, I. S.; Asadnia, M.; McAlpine, D.; Rabbitt, R. D.; Brown, D. J.
10.1101/2023.05.15.540767 — neuroscience — Posted on 2023-05-17
2061 Two neuronal models of TDP-43 proteinopathy display reduced axonal translation, increased oxidative stress, and defective exocytosis.
Pisciottani, A.; Croci, L.; Lauria, F.; Marullo, C.; Savino, E.; Ambrosi, A.; Podini, P.; Marchioretto, M.; Casoni, F.; Cremona, O.; Taverna, S.; Quattrini, A.; Cioni, J.-M.; Viero, G.; Codazzi, F.; Consalez, G. G.
10.1101/2023.05.17.540919 — neuroscience — Posted on 2023-05-17
2064 SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration
Thumu, S. C. R.; Jain, M.; Soman, S.; Das, S.; Verma, V.; Nandi, A.; Gutmann, D. H.; Jayaprakash, B.; Nair, D.; Clement, J. P.; Marathe, S.; Ramanan, N.
10.1101/2023.05.17.541074 — neuroscience — Posted on 2023-05-17
2065 The subjective amplitude of the diurnal rhythm matters - chronobiological insights for neuroimaging studies
Zareba, M. R.; Scislewska, P.; Fafrowicz, M.; Marek, T.; Oginska, H.; Szatkowska, I.; Beldzik, E.; Domagalik, A.
10.1101/2023.05.17.541153 — neuroscience — Posted on 2023-05-17
2066 Acute effect of transcranial direct current stimulation (tDCS) on postural control of trained athletes: a randomized controlled trial
Giancatarina, M.; Grandperrin, Y.; Nicolier, M.; Gimenez, P.; Vidal, C.; Tio, G.; Haffen, E.; Bennabi, D.; Grospretre, S.
10.1101/2023.05.17.541119 — neuroscience — Posted on 2023-05-17
2067 Distinct Local and Global Functions of Aβ Low-Threshold Mechanoreceptors in Mechanical Pain Transmission
Gautam, M.; Yamada, A.; Yamada, A. I.; Wu, Q.; Kridsada, K.; Ling, J.; Yu, H.; Dong, P.; Ma, M.; Gu, J.; Luo, W.
10.1101/2023.05.16.540962 — neuroscience — Posted on 2023-05-17
2068 Pathological Tau transmission initiated by binding lymphocyte-activation gene 3
Chen, C.; Kumbhar, R. R.; Wang, H.; Yang, X.; Gadhave, K.; Rastegar, C.; Kimura, Y.; Behensky, A.; Katakam, S.; Jeong, D.; Wang, L.; Wang, A.; Chen, R.; Zhang, S.; Jin, L.; Workman, C. J.; Vignali, D. A. A.; Pletinkova, O.; Nauen, D. W.; Wong, P. C.; Troncoso, J.; Ying, M.; Dawson, V. L.; Dawson, T.; Mao, X.
10.1101/2023.05.16.541015 — neuroscience — Posted on 2023-05-17
2073 Effects of lithium on locomotor activity and circadian rhythm of honey bees
Erdem, B.; Arslan, O. C.; Sevin, S.; Gozen, A. G.; Agosto, J. L.; Giray, T.; Alemdar, H.
10.1101/2023.05.17.541141 — neuroscience — Posted on 2023-05-17
2074 Vagus nerve stimulation rescues persistent pain following orthopedic surgery in adult mice.
Wu, P. Y.; Caceres, A. I.; Chen, J.; Sokoloff, J.; Huang, M.; Baht, G. S.; Nackley, A. G.; Jordt, S. E.; Terrando, N.
10.1101/2023.05.16.540949 — neuroscience — Posted on 2023-05-17
2075 Single nucleus transcriptomics of human and monkey striatum implicates DNA damage, neuroinflammation, and neurodegeneration signaling in opioid use disorder
Phan, B. N.; Ray, M. H.; Xue, X.; Fenster, R. J.; Kohut, S. J.; Bergman, J.; Haber, S. N.; Mccullough, K. M.; Kuppe-Fish, M. K.; Glausier, J. R.; Su, Q.; Tipton, A. E.; Lewis, D. A.; Freyberg, Z.; Tseng, G. C.; Ressler, K. J.; Russek, S. J.; Alekseyev, Y.; Seney, M. L.; Pfenning, A. R.; Logan, R. W.
10.1101/2023.05.17.541145 — neuroscience — Posted on 2023-05-17
2077 Estrogen receptor alpha mutations regulate gene expression and cell growth in breast cancer through microRNAs
Arnesen, S.; Polaski, J. T.; Blanchard, Z.; Osborne, K. S.; Welm, A. L.; O'Connell, R. M.; Gertz, J.
10.1101/2022.10.07.511340 — cancer biology — Posted on 2023-05-17
2079 Computational validation of clonal and subclonal copy number alterations from bulk tumour sequencing
Antonello, A.; Bergamin, R.; Calonaci, N.; Househam, J.; Milite, S.; Williams, M. J.; Anselmi, F.; d'Onofrio, A.; Sundaram, V.; Sosinsky, A.; Cross, W. C. H.; Caravagna, G.
10.1101/2021.02.13.429885 — bioinformatics — Posted on 2023-05-17
2082 Genome editing in the mouse brain with minimally immunogenic Cas9 RNPs
Stahl, E. C.; Sabo, J. K.; Kang, M. H.; Allen, R.; Applegate, E.; Kim, S. E.; Kwon, Y.; Seth, A.; Lemus, N.; Salinas-Rios, V.; Soczek, K.; Trinidad, M.; Vo, L. T.; Jeans, C.; Wozniak, A.; Morris, T.; Kimberlin, A.; Foti, T.; Savage, D. F.; Doudna, J. A.
10.1101/2023.04.13.536294 — bioengineering — Posted on 2023-05-17
2084 Near-chromosome level genome assembly of devil firefish, Pterois miles
Kitsoulis, C. V.; Papadogiannis, V.; Kristoffersen, J. B.; Kaitetzidou, E.; Sterioti, A.; Tsigenopoulos, C. S.; Manousaki, T.
10.1101/2023.01.10.523469 — genomics — Posted on 2023-05-17
2085 Towards the biogeography of butyrate-producing bacteria
Brame, J. E.; Liddicoat, C.; Abbott, C. A.; Edwards, R. A.; Robinson, J. M.; Gauthier, N. E.; Breed, M. F.
10.1101/2022.10.07.510278 — ecology — Posted on 2023-05-17
2086 Single cell transcriptomics of human prenatal anterior foregut-derived organs identifies distinct developmental signatures directing commitment and specialization of the thymic epithelial stroma
Mohammed, A.; Slepicka, P. F.; Solomon, B.; Hubka, K. M.; Nguyen, H. D.; Chavez, M. G.; Yeh, C. Y.; Winn, V. D.; Gifford, C. A.; Khatri, P.; Gentles, A.; Weinacht, K. G.
10.1101/2022.10.02.510339 — developmental biology — Posted on 2023-05-17
2088 Dkk2 interacts with Pax9 in palate mesenchyme to pattern and tune osteogenesis
Oliver Pina, J.; Roth, D. M.; Raju, R.; Winchester, E. W.; Chattaraj, P.; Kidwai, F. K.; Faucz, F. R.; Iben, J.; Padilla, C.; Cotney, J. L.; D'Souza, R. N.
10.1101/2023.05.16.541037 — developmental biology — Posted on 2023-05-17
2090 Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human primary intestinal epithelial cells
Bergsten, E.; Mestivier, D.; Donnadieu, F.; Pedron, T.; Barau, C.; Tsoumtsa, L.; Mettouchi, A.; Lemichez, E.; Gorgette, O.; Chamaillard, M.; Vaysse, A.; Volant, S.; Doukani, A.; Sansonetti, P. J.; Sobhani, I.; Nigro, G.
10.1101/2022.05.14.491935 — microbiology — Posted on 2023-05-17
2091 Allochthonous groundwater microorganisms affect coastal seawater microbial abundance, activity and diversity
Yanuka-Golub, K.; Belkin, N.; Weber, N.; Mayyani, M.; Levy, Y.; Reznik, I. J.; Rubin-Blum, M.; Rahav, E.; Kiro, Y.
10.1101/2023.05.14.540660 — microbiology — Posted on 2023-05-17
2093 An in vitro neurogenetics platform for precision disease modeling in the mouse
CORTES, D. E.; ESCUDERO, M.; MITRA, A.; KORGAN, A. C.; EDWARDS, A.; Aydin, S. C.; Munger, S. C.; O'CONNELL, K. M. S.; Reinholdt, L. G.; PERA, M. F.
10.1101/2022.01.21.477242 — neuroscience — Posted on 2023-05-17
2098 Power generation by a myosin-1 essential for endocytosis: implications for biological mechanism
Pedersen, R. T.; Snoberger, A.; Pyrpassopoulos, S.; Safer, D.; Drubin, D. G.; Ostap, E. M.
10.1101/2023.03.21.533689 — cell biology — Posted on 2023-05-17
2100 Novel Curcuphenol Analogues Possess Anti-Metastatic Biologic Activity
Ellis, S. L. S.; Nohara, L. L.; Dada, S.; Saranchova, I.; Munro, L.; Choi, K. B.; Garrovillas, E.; Pfeifer, C. G.; Williams, D. E.; Cheng, P.; Andersen, R. J.; Jefferies, W.
10.1101/2023.05.15.540833 — biochemistry — Posted on 2023-05-17
2106 CRACD loss promotes small cell lung cancer tumorigenesis via EZH2-mediated immune evasion
Zhang, S.; Kim, K.-B.; Huang, Y.; Kim, D.-W.; Kim, B.; Ko, K.-P.; Zou, G.; Zhang, J.; Jun, S.; Kirk, N. A.; Hwang, Y. E.; Ban, Y. H.; Chan, J. M.; Rudin, C. M.; Park, K.-S.; Park, J.-I.
10.1101/2023.02.15.528365 — cancer biology — Posted on 2023-05-17
2107 Native-state proteomics of Parvalbumin interneurons identifies novel molecular signatures and metabolic vulnerabilities to early Alzheimer's disease pathology
Kumar, P.; Goettemoeller, A. M.; Espinosa-Garcia, C.; Tobin, B. R.; Tfaily, A.; Nelson, R. S.; Natu, A.; Dammer, E. B.; Santiago, J. V.; Malepati, S.; Cheng, L.; Xiao, H.; Duong, D. D.; Seyfried, N. T.; Wood, L. B.; Rowan, M.; Rangaraju, S.
10.1101/2023.05.17.541038 — neuroscience — Posted on 2023-05-17
2109 Excitation creates a distributed pattern of cortical suppression due to varied recurrent input
O'Rawe, J. F.; Zhou, Z.; Li, A. J.; LaFosse, P. K.; Goldbach, H. C.; Histed, M. H.
10.1101/2022.08.31.505844 — neuroscience — Posted on 2023-05-17
2111 Single cell transcriptomics of human prenatal anterior foregut-derived organs identifies distinct developmental signatures directing commitment and specialization of the thymic epithelial stroma
Mohammed, A.; Slepicka, P. F.; Solomon, B.; Hubka, K. M.; Nguyen, H. D.; Chavez, M. G.; Yeh, C. Y.; Winn, V. D.; Gifford, C. A.; Khatri, P.; Gentles, A.; Weinacht, K. G.
10.1101/2022.10.02.510339 — developmental biology — Posted on 2023-05-17
2112 Temporal scaling of dopamine neuron firing and dopamine release by distinct ion channels shape behavior
Juarez, B.; Kong, M.-S.; Jo, Y. S.; Elum, J. E.; Yee, J. X.; Ng-Evans, S.; Cline, M.; Hunker, A. C.; Quinlan, M. A.; Baird, M. A.; Elerding, A. J.; Johnson, M.; Ban, D.; Mendez, A.; Goodwin, N.; Soden, M. E.; Zweifel, L.
10.1101/2021.08.27.457972 — neuroscience — Posted on 2023-05-17
2114 Overlapping representations of food and social stimuli in VTA dopamine neurons
Willmore, L.; Minerva, A.; Engelhard, B.; McMannon, B.; Oak, N.; Thiberge, S.; Murugan, M.; Pena, C. J.; Witten, I.
10.1101/2023.05.17.541104 — neuroscience — Posted on 2023-05-17
2115 Anticodon-like loop-mediated dimerization in the crystal structures of HDV- like CPEB3 ribozymes
Przytula-Mally, I.; Engilberge, S.; Johannsen, S.; Olieric, V.; Masquida, B.; Sigel, R. K. O.
10.1101/2022.09.22.508989 — biophysics — Posted on 2023-05-17
2117 Vasoactive Endothelial Growth Factor and Heat Shock Protein Gene Expression Response in Kawasaki Disease Associated Coronary Arteritis
Rashid, A.; Alkhzaimi, H.; Benakatti, G.; Malik, Z.; Sharma, V.; Sharma, A.; Malik, R.; Quraishi, N.; Shaikh, G.; Al-Dubai, A.; Hussain, A.
10.1101/2022.09.26.508411 — genomics — Posted on 2023-05-17
2121 SODAR: managing multi-omics study data and metadata
Nieminen, M.; Stolpe, O.; Kuhring, M.; Weiner, J.; Pett, P.; Beule, D.; Holtgrewe, M.
10.1101/2022.08.19.504516 — bioinformatics — Posted on 2023-05-17
2122 Aneurysmal Growth in Type-B Aortic Dissection: Assessing the Impact of Patient-Specific Inlet Conditions on Key Haemodynamic Indices
Stokes, C.; Ahmed, D.; Lind, N.; Haupt, F.; Becker, D.; Hamilton, J.; Muthurangu, V.; von Tengg-Kobligk, H.; Papadakis, G.; balabani, s.; Diaz, V.
10.1101/2023.02.12.528194 — bioengineering — Posted on 2023-05-17
2123 CK1δ homeostasis by activity-dependent shuttling and degradation of orphan kinase
Serrano, F. E.; Marzoll, D.; Ruppert, B.; Diernfellner, A. C. R.; Brunner, M.
10.1101/2023.02.13.528286 — biochemistry — Posted on 2023-05-17
2131 Hyperphosphorylated Tau Inflicts Intracellular Stress Responses That Are Mitigated by Apomorphine
Song, Z.; Wang, K.-W.; Hagar, H.-T. C.; Chen, H.-R.; Kuan, C.-Y.; Zhang, K.; Kuo, M.-H.
10.1101/2023.05.13.540661 — biochemistry — Posted on 2023-05-17
2133 Neural effects of TMS trains on the human prefrontal cortex
Ross, J. M.; Cline, C. C.; Sarkar, M.; Truong, J.; Keller, C. J.
10.1101/2023.01.30.526374 — neuroscience — Posted on 2023-05-17
2134 CyuR is a Dual Regulator for L-Cysteine Dependent Antimicrobial Resistance in Escherichia coli
Rodionova, I. A.; Lim, H.; Rodionov, D. A.; Hutchison, Y.; Dalldorf, C.; Gao, Y.; Monk, J.; Palsson, B. O.
10.1101/2023.05.16.541025 — systems biology — Posted on 2023-05-16
2135 Default Values And Read-Across Proposal For Dermal Absorption Based On Human Skin In Vitro Studies Dataset With Pesticides
Sarti, D. A.; Wagner, J.; Palma, F.; Kalvan, H.; Giachini, M. F.; Lautenschalaeger, D.; Lupianhez, V.; Pires, J. C.; Sales, M.; de Faria, P. M.; Bertomeu, L. C.; Le Bras, M.
10.1101/2023.05.11.540395 — pharmacology and toxicology — Posted on 2023-05-17
2136 FET fusion oncoproteins disrupt physiologic DNA repair networks in cancer
Menon, S.; Breese, M. R.; Lin, Y. P.; Allegakoen, H.; perati, s.; Heslin, A.; Horlbeck, M.; Weissman, J. S.; Sweet-Cordero, A.; Bivona, T.; Tulpule, A.
10.1101/2023.04.30.538578 — cancer biology — Posted on 2023-05-16
2137 Multiomic Profiling Reveals Metabolic Alterations Mediating Aberrant Platelet Activity and Inflammation in Myeloproliferative Neoplasms
He, F.; Laranjeira, A. B. A.; kong, t.; Liu, A.; Bark, K.; Lasky, N. M.; Fisher, D. A. C.; Cox, M. J.; Fulbright, M.; Heck, L. A.; Yu, L.; Sykes, S. M.; DAlessandro, A.; Di Paola, J.; Oh, S.
10.1101/2022.12.08.519689 — cancer biology — Posted on 2023-05-17
2138 Crumpled polymer with loops recapitulates key features of chromosome organization
Polovnikov, K. E.; Slavov, B.; Belan, S.; Imakaev, M.; Brandao, H.; Mirny, L. A.
10.1101/2022.02.01.478588 — biophysics — Posted on 2023-05-16
2143 Reciprocal discoidin domain receptor signaling strengthens integrin adhesion to connect adjacent tissues
Park, K.; Jayadev, R.; Payne, S. G.; Kenny-Ganzert, I. W.; Chi, Q.; Costa, D. S.; Ramos-Lewis, W.; Balachandar Thendral, S.; Sherwood, D. R.
10.1101/2023.03.14.532639 — developmental biology — Posted on 2023-05-17
2144 p53 controls choice between apoptotic and non-apoptotic death following DNA damage
Honeywell, M. E.; Isidor, M. S.; Harper, N. W.; Fontana, R. E.; Cruz-Gordillo, P.; Porto, S. A.; Fraser, C. S.; Sarosiek, K. A.; Guertin, D. A.; Spinelli, J. B.; Lee, M. J.
10.1101/2023.01.17.524444 — cell biology — Posted on 2023-05-17
2145 Comprehensively defining cellular specializations for initiating parallel auditory pathways in the mouse cochlear nucleus
Jing, J.; Hu, M.; Ngodup, T.; Ma, Q.; Lau, S. N. N.; Ljungberg, C.; McGinley, M. J.; Trussell, L. O.; Jiang, X.
10.1101/2023.05.15.539065 — neuroscience — Posted on 2023-05-16
2146 Prediction of Stroke Outcome in Mice Based on Non-Invasive MRI and Behavioral Testing
Knab, F.; Koch, S. P.; Major, S.; Farr, T. D.; Mueller, S.; Euskirchen, P.; Eggers, M.; Kuffner, M. T. C.; Walter, J.; Berchtold, D.; Knauss, S.; Dreier, J. P.; Meisel, A.; Endres, M.; Dirnagl, U.; Wenger, N.; Hoffmann, C.; Boehm-Sturm, P.; Harms, C.
10.1101/2022.05.13.491869 — neuroscience — Posted on 2023-05-16
2147 Reducing brain kynurenic acid synthesis precludes kynurenine-induced sleep disturbances
Rentschler, K. M.; Milosavljevic, S.; Baratta, A. M.; Wright, C. J.; Piroli, M. V.; Tentor, Z.; Valafar, H.; Pocivavsek, A.
10.1101/2022.11.21.517377 — neuroscience — Posted on 2023-05-17
2149 Pangenome analysis reveals the genetic basis for taxonomic classification of the Lactobacillaceae family
Rajput, A.; Chauhan, S. M.; Mohite, O. S.; Hyun, J. C.; Ardalani, O.; Jahn, L. J.; Sommer, M. O.; Palsson, B. O.
10.1101/2023.05.16.541042 — systems biology — Posted on 2023-05-16
2150 In silico design of DNA sequences for in vivo nucleosome positioning
Routhier, E.; Pierre, E.; Joubert, A.; Lancrey, A.; Boule, J.-B.; Mozziconacci, J.
10.1101/2023.05.15.540782 — synthetic biology — Posted on 2023-05-16
2152 Structural insights into human TFIIIC promoter recognition
Seifert Davila, W. H.; Girbig, M.; Hauptmann, L.; Hoffmann, T.; Eustermann, S.; Mueller, C.
10.1101/2023.05.16.540835 — molecular biology — Posted on 2023-05-16
2157 Stimulator of interferon genes is required for Toll-Like Receptor-8 induced interferon response
Garcia-Martinez, K. Y.; Chen, J.; Jones, J.; Woo, A.; Aucapina, E.; Brito, I. L.; Leifer, C. A.
10.1101/2023.05.15.540812 — immunology — Posted on 2023-05-16
2158 Synergistic activity of IL-2 mutein with tolerogenic ImmTOR nanoparticles leads to massive expansion of antigen-specific Tregs and protection against autoimmune disease
Kishimoto, T. K.; Fournier, M.; Michaud, A.; Rizzo, G.; Roy, C.; Capela, T.; Nukolova, N.; Li, N.; Doyle, L.; Fu, F.-n.; VanDyke, D.; Traber, P. G.; Spangler, J. B.; Leung, S. S.; Ilyinskii, P. O.
10.1101/2023.05.15.540840 — immunology — Posted on 2023-05-16
2159 Human light meromyosin mutations linked to skeletal myopathies disrupt the coiled coil structure and myosin head sequestration
Carrington, G.; Hau, A.; Kosta, S.; Dugdale, H.; Muntoni, F.; D'Amico, A.; Van den Bergh, P.; Romero, N.; Malfatti, E.; Vilchez, J. J.; Oldfors, A.; Pajusalu, S.; Ounap, K.; Giralt-Pujol, M.; Zanoteli, E.; Campbell, K.; Iwamoto, H.; Peckham, M.; Ochala, J.
10.1101/2023.05.15.540775 — physiology — Posted on 2023-05-16
2161 Structural basis of TFIIIC-dependent RNA Polymerase III transcription initiation
Talyzina, A.; Han, Y.; Banerjee, C.; Fishbain, S.; Reyes, A.; Vafabakhsh, R.; He, Y.
10.1101/2023.05.16.540967 — biophysics — Posted on 2023-05-16
2164 Analysis of lncRNA, miRNA, mRNA-associated ceRNA networks in Autism
Tabatabaie Azad, S. A.; Mehrabi, M.-R.; Zarinzad, Y.; Noori, A.; Nemati, H.; Shahbazi, A.; Badameh, P.; Mohammadnezad kenari, S. R.; Arabzadeh, P.; Javanmard, A.-R.
10.1101/2023.05.14.540737 — bioinformatics — Posted on 2023-05-16
2168 Cell source-derived variabilities in human juvenile chondrocyte-derived cell sheet cartilage regenerative effects in a nude rat chondral defect implantation model
Matsukura, K.; Kondo, M.; Metzler, N. F.; Ford, A. J.; Maak, T. G.; Hutchinson, D. T.; Wang, A. A.; Sato, M.; Grainger, D. W.; Okano, T.
10.1101/2023.05.16.540535 — bioengineering — Posted on 2023-05-16
2169 A synthetic delivery vector for mucosal vaccination
Billet, A.; Hadjerci, J.; Tran, T.; Kessler, P.; Ulmer, J.; Mourier, G.; Ghazarian, M.; Gonzalez, A.; Thai, R.; Urquia, P.; Vanbaelen, A.-C.; Meola, A.; Fernandez, I.; Deville-Foillard, S.; MacDonald, E.; Paolini, L.; Schmidt, F.; Rey, F. A.; Kay, M. S.; Tartour, E.; Servent, D.; Johannes, L.
10.1101/2023.05.15.540756 — biochemistry — Posted on 2023-05-16
2170 CoCl2 triggered pseudohypoxic stress induces proteasomal degradation of SIRT4 via polyubiquitination of lysines K78 and K299
Hampel, N.; Georgy, J.; Mehrabipour, M.; Lang, A.; Scheller, J.; Ahmadian, M. R.; Floss, D. M.; Piekorz, R. P.
10.1101/2023.05.16.540489 — biochemistry — Posted on 2023-05-16
2171 Exonuclease assisted mapping of protein-RNA interactions (ePRINT)
Hawkins, S.; Mondaini, A.; Namboori, S. C.; Javed, A.; Bhinge, A.
10.1101/2023.05.16.540978 — genomics — Posted on 2023-05-16
2172 The ENCODE4 long-read RNA-seq collection reveals distinct classes of transcript structure diversity
Reese, F.; Williams, B.; Balderrama-Gutierrez, G.; Wyman, D.; Celik, M. H.; Rebboah, E.; Rezaie, N.; Trout, D.; Razavi-Mohseni, M.; Jiang, Y.; Borsari, B.; Morabito, S.; Liang, H. Y.; McGill, C. J.; Rahmanian, S.; Sakr, J.; Jiang, S.; Zeng, W.; Carvalho, K.; Weimer, A. K.; Dionne, L. A.; McShane, A.; Bedi, K.; Elhajjajy, S. I.; Upchurch, S.; Jou, J.; Youngworth, I.; Gabdank, I.; Sud, P.; Jolanki, O.; Strattan, J. S.; Kagda, M. S.; Snyder, M. P.; Hitz, B. C.; Moore, J. E.; Weng, Z.; Bennett, D.; Reinholdt, L.; Ljungman, M.; Beer, M. A.; Gerstein, M. B.; Pachter, L.; Guigo, R.; Wold, B. J.; Mort
10.1101/2023.05.15.540865 — genomics — Posted on 2023-05-16
2176 Expression of transcription factors KLF2 and KLF4 is induced by the mammalian Golgi stress response
Sasaki, K.; Sakamoto, M.; Miyake, I.; Tanaka, R.; Tanaka, R.; Tanaka, A.; Terami, M.; Komori, R.; Taniguchi, M.; Wakabayashi, S.; Sakurai, H. T.; Yoshida, H.
10.1101/2023.05.16.541051 — cell biology — Posted on 2023-05-16
2178 Automated model building and protein identification in cryo-EM maps
Jamali, K.; Kall, L.; Zhang, R.; Brown, A.; Kimanius, D.; Scheres, S.
10.1101/2023.05.16.541002 — molecular biology — Posted on 2023-05-16
2179 UBL3 interaction with α-synuclein is downregulated by silencing MGST3
Yan, J.; Zhang, H.; Chen, B.; Ping, Y.; Islam, M. S.; Tomochika, Y.; Aramaki, S.; Sato, T.; Nagashima, Y.; Nakamura, T.; Kahyo, T.; Kaneda, D.; Ogawa, K.; Yoshida, M.; Setou, M.
10.1101/2023.05.15.540904 — molecular biology — Posted on 2023-05-16
2180 Amino acid supplementation confers protection to red blood cells prior to Plasmodium falciparum bystander stress
Binns, H. C.; Alipour, E.; Nahid, D. S.; Whitesides, J. F.; Cox, A. O.; Furdui, C. M.; Marrs, G. S.; Kim-Shapiro, D. B.; Cordy, R. J.
10.1101/2023.05.16.540951 — microbiology — Posted on 2023-05-16
2181 Transcriptome profiling of human colonic cells exposed to the gut pathobiont Streptococcus gallolyticus subsp. gallolyticus.
Pasquereau-Kotula, E.; du Merle, L.; Sismeiro, O.; Pietrosemoli, N.; Varet, H.; Legendre, R.; Trieu-Cuot, P.; Dramsi, S.
10.1101/2023.05.16.540927 — microbiology — Posted on 2023-05-16
2188 Urbanization and fragmentation interact to drive mutualism breakdown and the rise of unstable pathogenic communities in forest soil
Tatsumi, C.; Atherton, K. F.; Garvey, S.; Conrad-Rooney, E.; Morreale, L. L.; Hutyra, L. R.; Templer, P. H.; Bhatnagar, J.
10.1101/2023.05.16.540503 — ecology — Posted on 2023-05-16
2189 Assessment of Landbird Population Change in the Southeastern United States
Michel, N. L.; Demarest, D.; Jones-Farrand, T.; Gleason, J.; McKnight, K.; Wilson, R.
10.1101/2023.05.16.540449 — ecology — Posted on 2023-05-16
2190 Defining distinct RNA-protein interactomes of SARS-CoV-2 genomic and subgenomic RNAs
Whitworth, I. T.; Knoener, R.; Puray Chavez, M.; Halfmann, P.; Romero, S.; Baddouh, M.; Scalf, M.; Kawaoka, Y.; Kutluay, S. B.; Smith, L. M.; Sherer, N. M.
10.1101/2023.05.15.540806 — molecular biology — Posted on 2023-05-16
2193 Growth and tension in explosive fruit
Mosca, G.; Eng, R.; Adibi, M.; Yoshida, S.; Lane, B.; Bergheim, L.; Weber, G.; Smith, R. S.; Hay, A.
10.1101/2023.05.15.540759 — plant biology — Posted on 2023-05-16
2194 CpG island turnover events predict evolutionary changes in enhancer activity
Kocher, A. A.; Dutrow, E. V.; Uebbing, S.; Yim, K. M.; Larios, M. F. R.; Baumgartner, M.; Nottoli, T.; Noonan, J. P.
10.1101/2023.05.09.540063 — genetics — Posted on 2023-05-16
2197 Determinants of Motor Neuron Functional Subtypes Important for Locomotor Speed
D'Elia, K. P.; Hameedy, H.; Goldblatt, D.; Frazel, P.; Kriese, M.; Zhu, Y.; Hamling, K. R.; Kawakami, K.; Liddelow, S. A.; Schoppik, D.; Dasen, J. S.
10.1101/2022.12.23.521820 — neuroscience — Posted on 2023-05-16
2198 Cell-type-specific nuclear morphology predicts genomic instability and prognosis in multiple cancer types
Abel, J.; Jain, S.; Rajan, D.; Padigela, H.; Leidal, K.; Prakash, A.; Conway, J.; Nercessian, M.; Kirkup, C.; Javed, S. A.; Egger, R.; Trotter, B.; Gerardin, Y.; Brosnan-Cashman, J. A.; Dhoot, A.; Montalto, M. C.; Wapinski, I.; Khosla, A.; Drage, M. G.; Yu, L.; Taylor-Weiner, A.
10.1101/2023.05.15.539600 — cancer biology — Posted on 2023-05-16
2200 Interchromosomal segmental duplication drives translocation and loss of P. falciparum histidine-rich protein 3
Hathaway, N. J.; Kim, I. E.; Young, N. W.; Hui, S. T.; Crudale, R.; Giesbrecht, D.; Liang, E. Y.; Nixon, C. P.; Juliano, J. J.; Parr, J. B.; Bailey, J. A.
10.1101/2022.12.07.519189 — genomics — Posted on 2023-05-16
2201 Stable expression of Helicobacter pylori cagA oncoprotein in brinjal
Mehran, M. J.; Barzigar, R.; Basaralu Yadurappa, S. K.; Haraprasad, N.; Fakrudin, B.; Paul, S.; Ramasamy, R. K.; Malla, S.
10.1101/2023.05.12.540570 — molecular biology — Posted on 2023-05-16
2205 Progress in elementary school reading linked to growthof cortical responses to familiar letter combinationswithin visual word forms
Wang, F.; Kaneshiro, B.; Toomarian, E. Y.; Gosavia, R. S.; Hasak, L. R.; Moron, S.; Nguyen, Q. T. H.; Norcia, A. M.; McCandliss, B.
10.1101/2022.11.08.515712 — scientific communication and education — Posted on 2023-05-16
2206 Default Values And Read-Across Proposal For Dermal Absorption Based On Human Skin In Vitro Studies Dataset With Pesticides
Sarti, D. A.; Wagner, J.; Palma, F.; Kalvan, H.; Giachini, M. F.; Lautenschalaeger, D.; Lupianhez, V.; Pires, J. C.; Sales, M.; de Faria, P. M.; Bertomeu, L. C.; Le Bras, M.
10.1101/2023.05.11.540395 — pharmacology and toxicology — Posted on 2023-05-16
2207 In vivo seamless genetic engineering via CRISPR-triggered single-strand annealing
Aguilar, G.; Bauer, M.; Vigano, M. A.; Schnider, S. T.; Brugger, L.; Jimenez-Jimenez, C.; Guerrero, I.; Affolter, M.
10.1101/2022.06.17.496589 — genetics — Posted on 2023-05-16
2208 No fitness impact of the knockout of the two main components of mimivirus genomic fiber and fibril layer
Alempic, J.-M.; Bisio, H.; Villalta, A.; Santini, S.; Lartigue, A.; Schmitt, A.; Bugnot, C.; Notaro, A.; BELMUDES, L.; Adrait, A.; Poirot, O.; Ptchelkine, D.; De Castro, C.; Coute, Y.; Abergel, C.
10.1101/2023.04.28.538727 — microbiology — Posted on 2023-05-16
2209 Interaction of amisulpride with GLUT1 at the blood-brain barrier. Relevance to Alzheimer's disease
Boyanova, S. T.; LLoyd-Morris, E.; Corpe, C.; Rahman, K. M.; Farag, D. B.; Page, L.; Wang, H.; Fleckney, A. L.; Gatt, A.; Troakes, C.; Vizcay-Barrena, G.; Fleck, R.; Reeves, S. J.; Thomas, S. A.
10.1101/2023.05.15.540749 — neuroscience — Posted on 2023-05-16
2211 Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model
Martin-Flores, N.; Podpolny, M.; McLeod, F.; Workman, I.; Crawford, K.; Ivanov, D.; Leonenko, G.; Escott-Price, V.; Salinas, P. C.
10.1101/2022.06.16.495307 — neuroscience — Posted on 2023-05-16
2212 Antimicrobial wound care in an ant society
Frank, E. T.; Kesner, L.; Liberti, J.; Helleu, Q.; LeBoeuf, A.; Dascalu, A.; Sponsler, D.; Azuma, F.; Economo, E.; Waridel, P.; Engel, P.; Schmitt, T.; Keller, L.
10.1101/2022.04.26.489514 — animal behavior and cognition — Posted on 2023-05-16
2216 Loss of genome maintenance accelerates podocyte damage
Braun, F.; Mandel, A. M.; Blomberg, L.; Wong, M. N.; Chatzinikolaou, G.; Nair, V.; Akbar-Hase, R. A.; Puelles, V. G.; Meyer, D. H.; McCown, P. J.; Haas, F.; Rahmatollahi, M.; Fermin, D.; Slaats, G.; Bork, T.; Schell, C.; Koehler, S.; Brinkkoetter, P.; Lindenmeyer, M. T.; Cohen, C.; Kann, M.; Bloch, W.; Sampson, M. G.; Dolle, M. E.; Kretzler, M.; Garinis, G. A.; Huber, T. B.; Schermer, B.; Benzing, T.; Schumacher, B.; Kurschat, C. E.
10.1101/2020.09.13.295303 — cell biology — Posted on 2023-05-16
2217 Unidirectional protein recruitment is essential for viral latency
Lavi, I.; Bhattacharya, S.; Awase, A.; Orgil, O.; Avital, N.; Journo, G.; Gurevich, V.; Shamay, M.
10.1101/2021.10.10.463816 — microbiology — Posted on 2023-05-16
2218 MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type-I IFN responses via Brd4 and is involved in ALS
Perez-Cabello, J. A.; Silvera-Carrasco, L.; Franco, J. M.; Capilla-Gonzalez, V.; Armaos, A.; Gomez-Lima, M.; Garcia-Garcia, R.; Yap, X. W.; Leal-Lasarte, M. M.; Lall, D.; Baloh, R. H.; Martinez, S.; Miyata, Y.; Tartaglia, G. G.; Sawarkar, R.; Garcia-Dominguez, M.; Pozo, D.; Roodveldt, C.
10.1101/2023.01.23.524851 — neuroscience — Posted on 2023-05-16
2219 HISTONE DEACETYLASE 19 REGULATES SHOOT MERISTEMLESS EXPRESSION IN THE CARPEL MARGIN MERISTEM CONTRIBUTING TO OVULE NUMBER DETERMINATION AND TRANSMITTING TRACT DIFFERENTIATION
Manrique, S.; Cavalleri, A.; Guazzotti, A.; Villarino, G. H.; Simonini, S.; Bombarely, A.; Higashiyama, T.; Grossniklaus, U.; Mizzotti, C.; Pereira, A. M.; Coimbra, S.; Sankaranarayanan, S.; Onelli, E.; Masiero, S.; Franks, R. G.; Colombo, L.
10.1101/2023.05.08.537343 — plant biology — Posted on 2023-05-16
2221 Dietary fibre reverses adverse post-stroke outcomes in mice via short-chain fatty acids and its sensing receptors GPR41, GPR43 and GPR109A
Peh, A.; Dinakis, E.; Jama, H.; Anderson, D.; Creek, D. J.; Zheng, G.; Veer, M. d.; Mackay, C. R.; Zheng, T.; Kemp-Harper, B. K.; Broughton, B. R. S.; Marques, F. Z.
10.1101/2023.05.15.540735 — neuroscience — Posted on 2023-05-16
2224 Revealing the spacetime hierarchical whole-brain dynamics of auditory predictive coding
Bonetti, L.; Fernandez-Rubio, G.; Carlomagno, F.; Pantazis, D.; Vuust, P.; Kringelbach, M. L.
10.1101/2022.11.19.517195 — neuroscience — Posted on 2023-05-16
2228 Deciphering molecular heterogeneity and dynamics of neural stem cells in human hippocampal development, aging, and injury
Yao, J.; Dai, S.; Zhu, R.; Tan, J.; Zhao, Q.; Yin, Y.; Sun, J.; Du, X.; Ge, L.; Xu, J.; Hou, C.; Li, N.; Li, J.; Ji, W.; Zhu, C.; Zhang, R.; Li, T.
10.1101/2023.05.15.540723 — neuroscience — Posted on 2023-05-16
2229 SARS-CoV-2 evolution in the absence of selective immune pressures, results in antibody resistance, interferon suppression and phenotypic differences by lineage
Willett, J. D. S.; Gravel, A.; Dubuc, I.; Gudimard, L.; dos Santos Pereira Andrade, A. C.; Lacasse, E.; Fortin, P.; Liu, J.-L.; Cervantes, J. A.; Galvez, J. H.; Djambazian, H.; Zwaig, M.; Roy, A.-M.; Lee, S.; Chen, S.-H.; Ragoussis, I.; Flamand, L.
10.1101/2023.01.16.523994 — genetics — Posted on 2023-05-16
2232 Diffusion Tensor Imaging: Influence of segmentation on fiber tracking in the supraspinatus muscle - an inter-operator reliability analysis
Vetter, S.; Köhler, H.-P.; Hepp, P.; Steinke, H.; Schleifenbaum, S.; Theopold, J.; Kiem, S.; Witt, M.; Henkelmann, J.; Roth, C.
10.1101/2023.05.15.540752 — physiology — Posted on 2023-05-16
2233 A progesterone derivative linked to a stable phospholipid activates breast cancer cell response without leaving the cell membrane
Font-Mateu, J.; Sanllehi, P.; Sot, J.; Abad, B.; Mateos, N.; Torreno-Pina, J. A.; Ferrari, R.; Wright, R. H. G.; Garcia-Parajo, M. F.; Joglar, J.; Goni, F. M.; Beato, M.
10.1101/2023.05.14.540708 — genomics — Posted on 2023-05-16
2234 Interaction of amisulpride with GLUT1 at the blood-brain barrier. Relevance to Alzheimer's disease
Boyanova, S. T.; LLoyd-Morris, E.; Corpe, C.; Rahman, K. M.; Farag, D. B.; Page, L.; Wang, H.; Fleckney, A. L.; Gatt, A.; Troakes, C.; Vizcay-Barrena, G.; Fleck, R.; Reeves, S. J.; Thomas, S. A.
10.1101/2023.05.15.540749 — neuroscience — Posted on 2023-05-16
2238 When Do Visual Category Representations Emerge in Infants' Brains?
Yan, X.; Tung, S.; Fascendini, B.; Chen, Y. D.; Norcia, A. M.; Grill-Spector, K.
10.1101/2023.05.11.539934 — neuroscience — Posted on 2023-05-16
2241 A eukaryote-specific factor mediates an early step in the assembly of plant photosystem II
Armbruster, U.; Keller, J.-M.; Frieboes, M. J.; Jödecke, L.; Kappel, S.; Rindfleisch, T.; Sandoval-Ibanez, O.; Gerlach, I.; Thiele, W.; Bock, R.; Eirich, J.; Finkemeier, I.; Schünemann, D.; Zoschke, R.; Schöttler, M. A.
10.1101/2023.05.12.540541 — plant biology — Posted on 2023-05-16
2242 Vitamin D induces SIRT1 activation through K610 deacetylation in colon cancer
Garcia-Martinez, J. M.; Chocarro-Calvo, A.; Martinez-Useros, J.; Fernandez-Acenero, M. J.; Fiuza, M. C.; Caceres-Rentero, J.; De la Vieja, A.; Barbachano, A.; Munoz, A.; Larriba, M. J.; Garcia Jimenez, C.
10.1101/2023.02.22.529558 — cancer biology — Posted on 2023-05-16
2243 Axis convergence in C. elegans embryos
Bhatnagar, A.; Nestler, M.; Gross, P.; Kramar, M.; Leaver, M.; Voigt, A.; Grill, S. W.
10.1101/2023.03.27.534329 — biophysics — Posted on 2023-05-16
2244 CAAStools, a toolbox to identify and test Convergent Amino Acid Substitutions.
Barteri, F.; Valenzuela, A.; Farre, X.; Juan, D.; Muntane, G.; Esteve-Altava, B.; Navarro, A.
10.1101/2022.12.14.520422 — bioinformatics — Posted on 2023-05-16
2247 Profiling ubiquitin signaling with UBIMAX reveals DNA damage- and SCFβTRCP-dependent ubiquitylation of the actin-organizing protein Dbn1
Colding-Christensen, C. S.; Kakulidis, E. S.; Arroyo-Gomez, J.; Hendriks, I. A.; Arkinson, C.; Fabian, Z.; Gambus, A.; Mailand, N.; Duxin, J.; Nielsen, M. L.
10.1101/2023.05.15.540799 — molecular biology — Posted on 2023-05-16
2248 Immune Digital Twin Blueprint: A Comprehensive Simulatable Model of the Human Immune System
Moore, R.; Amin, R.; Aghamiri, S.; Mohammed, A.; La Fleur, A.; Puniya, B. L.; Helikar, T.
10.1101/2020.03.11.988238 — systems biology — Posted on 2023-05-16
2249 Metabolic consequences of non-severe burn injury are associated with increased plasma markers of inflammation and cardiovascular disease risk.
Ryan, M. J.; Raby, E.; Masuda, R.; Lodge, S.; Nitschke, P.; Maker, G. L.; Wist, J.; Holmes, E.; Whiley, L.; Wood, F. M.; Nicholson, J. K.; Fear, M. W.; Gray, N.
10.1101/2023.04.24.537960 — systems biology — Posted on 2023-05-16
2250 A megaprotein brake for aging and insulin-mTOR signaling
Pandey, T.; Wang, B.; Wang, C.; Zu, J.; Deng, H.; Shen, K.; Vale, G.; McDonald, J. G.; Ma, D. K.
10.1101/2023.02.14.528431 — physiology — Posted on 2023-05-16
2251 Differences in 5'untranslated regions highlight the importance of translational regulation of dosage sensitive genes
Wieder, N.; D'Souza, E. N.; Martin-Geary, A. C.; Lassen, F. H.; Talbot-Martin, J.; Fernandes, M.; Chothani, S. P.; Rackham, O. J. L.; Schafer, S.; Aspden, J. L.; MacArthur, D. G.; Davies, R. W.; Whiffin, N.
10.1101/2023.05.15.540809 — genomics — Posted on 2023-05-15
2252 A comprehensive catalog of 3D genome organization in diverse human genomes facilitates understanding of the impact of structural variation on chromatin structure
Li, C.; Bonder, M. J.; Syed, S.; Human Genome Structural Variation Consortium (HGSVC), ; HGSVC Functional Analysis Working Group, ; Zody, M. C.; Chaisson, M. J. P.; Talkowski, M. E.; Marschall, T.; Korbel, J. O.; Eichler, E. E.; Lee, C.; Shi, X.
10.1101/2023.05.15.540856 — genomics — Posted on 2023-05-15
2255 Hierarchical syntax models of music predict theta power during music listening
Herff, S. A.; Bonetti, L.; Cecchetti, G.; Vuust, P.; Kringelbach, M. L.; Rohrmeier, M. A.
10.1101/2023.05.15.540878 — neuroscience — Posted on 2023-05-15
2256 On the Quina side: A Neanderthal bone industry at Chez-Pinaud site, France
Baumann, M.; Plisson, H.; Maury, S.; Renou, S.; Coqueugniot, H.; Vanderesse, N.; Kolobova, K. A.; Shnaider, S.; Rots, V.; Guerin, G.; Rendu, W.
10.1101/2023.05.15.540772 — paleontology — Posted on 2023-05-15
2259 The p97/VCP adapter UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions
Braxton, J. R.; Altobelli, C. R.; Tucker, M. R.; Tse, E.; Thwin, A. C.; Arkin, M. R.; Southworth, D. R.
10.1101/2023.05.15.540864 — biochemistry — Posted on 2023-05-15
2264 A new antibiotic from an uncultured bacterium binds to an immutable target
Shukla, R.; Peoples, A. J.; Ludwig, K. C.; Maity, S.; Derks, M. G. N.; Krueger, A. M.; de Benedetti, S.; Vermeulen, B. J. A.; Honorato, R. V.; Grein, F.; Lavore, F.; Bonvin, A. M. J. J.; Kubitscheck, U.; Breukink, E.; Achorn, C.; Nitti, A.; Schwalen, C. J.; Spoering, A. L.; Ling, L. L.; Hughes, D.; Lelli, M.; Roos, W. H.; Lewis, K.; Schneider, T.; Weingarth, M.
10.1101/2023.05.15.540765 — microbiology — Posted on 2023-05-15
2265 A Virus-like particle-based bivalent PCSK9 vaccine lowers LDL-cholesterol levels in Non-Human Primates
Fowler, A.; Van Rompay, K. K. A.; Sampson, M.; Leo, J.; Watanabe, J. K.; Usachenko, J. L.; Immareddy, R.; Lovato, D. M.; Schiller, J. T.; Remaley, A. T.; Chackerian, B.
10.1101/2023.05.15.540560 — immunology — Posted on 2023-05-15
2268 Generalizing Stepping Concepts To Non-Straight Walking
Dingwell, J. B.; Render, A. C.; Desmet, D. M.; Cusumano, J. P.
10.1101/2023.05.15.540644 — neuroscience — Posted on 2023-05-15
2269 Cell-type-specific nuclear morphology predicts genomic instability and prognosis in multiple cancer types
Abel, J.; Jain, S.; Rajan, D.; Padigela, H.; Leidal, K.; Prakash, A.; Conway, J.; Nercessian, M.; Kirkup, C.; Javed, S. A.; Egger, R.; Trotter, B.; Gerardin, Y.; Brosnan-Cashman, J. A.; Dhoot, A.; Montalto, M. C.; Wapinski, I.; Khosla, A.; Drage, M. G.; Yu, L.; Taylor-Weiner, A.
10.1101/2023.05.15.539600 — cancer biology — Posted on 2023-05-15
2270 Capturing the mechanosensitivity of cell proliferation in models of epithelium
Hollring, K.; Nuic, L.; Rogic, L.; Kaliman, S.; Gehrer, S.; Wollnik, C.; Rehfeldt, F.; Hubert, M.; Smith, A.-S.
10.1101/2023.01.31.526438 — biophysics — Posted on 2023-05-15
2271 Annotating Macromolecular Complexes in the Protein Data Bank: Improving the FAIRness of Structure Data
Appasamy, S. D.; Berrisford, J.; Gaborova, R.; Nair, S.; Anyango, S.; Grudinin, S.; Deshpande, M.; Armstrong, D.; Pidruchna, I.; Ellaway, J. I. J.; Leines, G. D.; Gupta, D.; Harrus, D.; Varadi, M.; Velankar, S.
10.1101/2023.05.15.540692 — bioinformatics — Posted on 2023-05-15
2275 Chemobiosis reveals tardigrade tun formation is dependent on reversible cysteine oxidation
Smythers, A. L.; Joseph, K. M.; O'Dell, H. M.; Clark, T. A.; Crislip, J. R.; Flinn, B. B.; Daughtridge, M. H.; Stair, E. R.; Mubarek, S. N.; Lewis, H. C.; Kolling, D. R.; Hicks, L. M.
10.1101/2023.05.15.540801 — biochemistry — Posted on 2023-05-15
2277 The Prolonged Terminal Phase of Human Life Induces Survival Response in the Skin Transcriptome
Abouhashem, A. S.; Singh, K.; Srivastava, R.; Liu, S.; Mathew-Steiner, S. S.; Gu, X.; Kacar, S.; Hagar, A.; Sandusky, G. E.; Roy, S.; Wan, J.; Sen, C. K.
10.1101/2023.05.15.540715 — genomics — Posted on 2023-05-15
2284 Cardiopharyngeal Mesoderm specification into cardiac and skeletal muscle lineages in gastruloids.
Argiro, L.; Chevalier, C.; Choquet, C.; Nandkishore, N.; Ghata, A.; Baudot, A.; Zaffran, S.; Lescroart, F.
10.1101/2023.05.15.540476 — developmental biology — Posted on 2023-05-15
2286 Dysfunctional Mitochondria in Cardiac Fibers of a Williams-Beuren Syndrome Mouse Model
Abdalla, N.; Tobias-Baraja, E.; Gonzalez, A.; Garrabou, G.; Egea, G.; Campuzano, V.
10.1101/2023.05.15.540778 — molecular biology — Posted on 2023-05-15
2287 Functional Exploration of Conserved Sequences in the Distal Face of Angiotensinogen
Amioka, N.; Wu, C.-H.; Sawada, H.; Ito, S.; Pettey, A.; Wu, C.; Moorleghen, J. J.; Howatt, D. A.; Graf, G.; Kooi, C. W. V.; Daugherty, A.; Lu, H. S.
10.1101/2022.12.22.521618 — molecular biology — Posted on 2023-05-15
2288 Differentiating Agonists and Competitive Antagonists of the Serotonin Type 3A (5-HT3A) Receptor
Davolio, A. J.; Jankowski, W. J.; Varnai, C.; Irwin, B. W. J.; Payne, M. C.; Chau, P. L.
10.1101/2023.05.15.540789 — molecular biology — Posted on 2023-05-15
2289 Lipase-mediated detoxification of host-derived antimicrobial fatty acids by Staphylococcus aureus
Kengmo Tchoupa, A.; Elsherbini, A. M. A.; Fu, X.; Ghaneme, O.; Seibert, L.; Boecker, M. A.; Lebtig, M.; Camus, J.; Papadopoulos Lambidis, S.; Schittek, B.; Kretschmer, D.; Laemmerhofer, M.; Peschel, A.
10.1101/2023.05.15.540481 — microbiology — Posted on 2023-05-15
2290 HIC1 interacts with FOXP3 multi-protein complex: a novel mechanism to regulate human regulatory T cell differentiation and function
Andrabi, S. B. A.; Batkulwar, K.; Bhosale, S. D.; Moulder, R.; Khan, M. H.; Buchacher, T.; Khan, M. M.; Rasool, O.; Kalim, U. U.; Lahesmaa, R.
10.1101/2023.05.15.540505 — immunology — Posted on 2023-05-15
2291 Enhancers that regulate TNF gene transcription in human macrophages in response to TLR3 stimulation
Gao, J.; Li, Y.; Zhao, D.; Guan, X.; Motsinger, K.; Scott-Browne, J.; Chu, H. W.; Huang, H.
10.1101/2022.06.13.496019 — immunology — Posted on 2023-05-15
2292 TREM2 limits necrotic core formation during atherogenesis by controlling macrophage survival and efferocytosis
Piollet, M.; Porsch, F.; Rizzo, G.; Kapser, F.; Schulz, D. J.; Kiss, M. G.; Schlepckow, K.; Morenas-Rodriguez, E.; Sen, M. O.; Gropper, J.; Roesch, M.; Goederle, L.; Hladik, A.; Knapp, S.; Colonna, M.; Martini, R.; Haass, C.; Zernecke, A.; Binder, C. J.; Cochain, C.
10.1101/2023.05.15.539977 — immunology — Posted on 2023-05-15
2296 Optogenetic spatial patterning of cooperation in yeast populations
Le Bec, M.; Pouzet, S.; Cordier, C.; Barral, S.; Scolari, V.; Sorre, B.; Banderas, A.; Hersen, P.
10.1101/2023.05.15.540783 — synthetic biology — Posted on 2023-05-15
2298 Robust biomarker discovery through multiplatform multiplex image analysis of breast cancer clinical cohorts
Eng, J. R.; Bucher, E.; Hu, Z.; Sanders, M.; Chakravarthy, B.; Gonzalez, P.; Pietenpol, J. A.; Gibbs, S. L.; Sears, R. C.; Chin, K.
10.1101/2023.01.31.525753 — cancer biology — Posted on 2023-05-15
2300 Microtubules under mechanical pressure can breach dense actin networks
Gelin, M.; Schaeffer, A.; Gaillard, J.; Guerin, C.; Vianay, B.; Orhant-Prioux, M.; Braun, M.; Leterrier, C.; Blanchoin, L.; THERY, M.
10.1101/2023.05.15.540482 — biophysics — Posted on 2023-05-15
2303 Complete Synthesis and Stereochemical Assignment of Novel Curcuphenol Analogues Possessing Anti-Metastatic Cancer Biological Activity
Ellis, S. L. S.; Nohara, L. L.; Dada, S.; Saranchova, I.; Munro, L.; Choi, K. B.; Garrovillas, E.; Pfeifer, C. G.; Williams, D. E.; Cheng, P.; Andersen, R. J.; Jefferies, W.
10.1101/2023.05.15.540833 — biochemistry — Posted on 2023-05-15
2305 Stability Oracle: A Structure-Based Graph-Transformer for Identifying Stabilizing Mutations
Diaz, D. J.; Gong, C.; Ouyang-Zhang, J.; Loy, J. M.; Wells, J. T.; Yang, D.; Ellington, A. J.; Dimakis, A.; Klivans, A. R.
10.1101/2023.05.15.540857 — biochemistry — Posted on 2023-05-15
2307 In vivo seamless genetic engineering via CRISPR-triggered single-strand annealing
Aguilar, G.; Bauer, M.; Vigano, M. A.; Schnider, S. T.; Brugger, L.; Jimenez-Jimenez, C.; Guerrero, I.; Affolter, M.
10.1101/2022.06.17.496589 — genetics — Posted on 2023-05-15
2308 Pyrethroid susceptibility reversal in Aedes aegypti: a longitudinal study in Tapachula, Mexico
Penilla-Navarro, P.; Solis-Santoyo, F.; Lopez-Solis, A.; Rodriguez, A. D.; Vera-Maloof, F.; Lozano, S.; Contreras-Mejia, E.; Vazquez-Samayoa, G.; Torreblanca-Lopez, R.; Perera, R.; Black, W. C.; Saavedra-Rodriguez, K.
10.1101/2023.05.11.540334 — evolutionary biology — Posted on 2023-05-15
2309 Colonisation debt: when invasion history impacts current range expansion
Morel-Journel, T.; Haond, M.; Duan, L.; Mailleret, L.; Vercken, E.
10.1101/2022.11.13.516255 — ecology — Posted on 2023-05-15
2310 Disentangling top-down drivers of mortality underlying diel population dynamics of Prochlorococcus in the North Pacific Subtropical Gyre
Beckett, S. J.; Demory, D.; Coenen, A. R.; Casey, J. R.; Dugenne, M.; Follett, C. L.; Connell, P.; Carlson, M. C. G.; Hu, S. K.; Wilson, S. T.; Muratore, D.; Rodriguez-Gonzalez, R. A.; Peng, S.; Becker, K. W.; Mende, D. R.; Armbrust, E. V.; Caron, D. A.; Lindell, D.; White, A. E.; Ribalet, F.; Weitz, J. S.
10.1101/2021.06.15.448546 — ecology — Posted on 2023-05-15
2311 Ciliary ARL13B inhibits developmental kidney cystogenesis in mouse
Van Sciver, R. E.; Long, A. B.; Katz, H. G.; Gigante, E. D.; Caspary, T.
10.1101/2023.02.08.527739 — developmental biology — Posted on 2023-05-15
2312 Contact sites between endoplasmic reticulum sheets and mitochondria regulate mitochondrial DNA replication and segregation
Ilamathi, H. S.; Benhammouda, S.; Lounas, A.; Al-Naemi, K.; Desrochers-Goyette, J.; Lines, M. A.; Richard, F.; Vogel, J.; Germain, M.
10.1101/2021.12.09.472002 — cell biology — Posted on 2023-05-15
2314 Antagonism and selective modulation of the human glucocorticoid receptor both reduce recruitment of p300/CBP and the Mediator complex
Van Moortel, L.; Verhee, A.; Houtman, R.; Melchers, D.; Delhaye, L.; Thommis, J.; Gevaert, K.; Eyckerman, S.; De Bosscher, K.
10.1101/2023.05.15.540854 — molecular biology — Posted on 2023-05-15
2315 UBL3 Interacts with Alpha-synuclein in Cells and the Interaction is Downregulated by the EGFR Pathway Inhibitor Osimertinib
Chen, B.; Hasan, M.; Zhang, H.; Zhai, Q.; WALIULLAH, A. S. M.; Ping, Y.; Zhang, C.; Oyama, S.; Afsana, M. M.; Tomochika, Y.; Nagashima, Y.; Nakamura, T.; Kahyo, T.; Ogawa, K.; Kaneda, D.; Yoshida, M.; Setou, M.
10.1101/2023.05.15.540732 — molecular biology — Posted on 2023-05-15
2317 KIS counteracts PTBP2 and regulates alternative exon usage in neurons
Moreno-Aguilera, M.; Mendoza, M. B.; Neher, A. M.; Dodel, M.; Mardakheh, F. K.; Ortiz, R.; Gallego, C.
10.1101/2023.05.15.540804 — molecular biology — Posted on 2023-05-15
2318 Profiling ubiquitin signaling with UBIMAX reveals DNA damage- and SCFβTRCP-dependent ubiquitylation of the actin-organizing protein Dbn1
Colding-Christensen, C. S.; Kakulidis, E. S.; Arroyo-Gomez, J.; Hendriks, I. A.; Arkinson, C.; Fabian, Z.; Gambus, A.; Mailand, N.; Duxin, J.; Nielsen, M. L.
10.1101/2023.05.15.540799 — molecular biology — Posted on 2023-05-15
2319 Microbes with higher metabolic independence are enriched in human gut microbiomes under stress
Veseli, I.; Chen, Y. T.; Schechter, M. S.; Vanni, C.; Fogarty, E. C.; Watson, A. R.; Jabri, B. A.; Blekhman, R.; Willis, A. D.; Yu, M. K.; Fernandez-Guerra, A.; Fussel, J.; Eren, A. M.
10.1101/2023.05.10.540289 — microbiology — Posted on 2023-05-15
2320 Combining Bacteriophage and Vancomycin is Efficacious Against MRSA biofilm-like Aggregates Formed in Synovial Fluid
Taha, M.; Arnaud, T.; Theriault, S. S.; Peters, D.; Wang, L.; Chen, W.; Lightly, T.; Cook, B. W. M.; Abdelbary, H.
10.1101/2023.05.15.540793 — microbiology — Posted on 2023-05-15
2322 A Study of Microbial Diversity in a Biofertilizer Consortium
Hernandez-Alvarez, C.; Peimbert, M.; Rodriguez-Martin, P.; Trejo-Aguilar, D.; Alcaraz, L. D.
10.1101/2023.05.15.540786 — microbiology — Posted on 2023-05-15
2325 Comprehensively defining cellular specializations for initiating parallel auditory pathways in the mouse cochlear nucleus
Jing, J.; Hu, M.; Ngodup, T.; Ma, Q.; Lau, S. N. N.; Ljungberg, C.; McGinley, M. J.; Trussell, L. O.; Jiang, X.
10.1101/2023.05.15.539065 — neuroscience — Posted on 2023-05-15
2326 Metformin Impairs Intestinal Fructose Metabolism
Tong, W.; Hannou, S. A.; Sargsyan, A.; Zhang, G.-F.; Grimsrud, P. A.; Astapova, I.; Herman, M. A.
10.1101/2023.04.17.537251 — physiology — Posted on 2023-05-15
2330 Molecular and evolutionary basis of O-antigenic polysaccharide driven phage sensitivity in environmental pseudomonads
Vacheron, J.; Heiman, C. M.; Garneau, J. R.; Kupferschmied, P.; deJonge, R.; Garrido-Sanz, D.; Keel, C.
10.1101/2023.05.15.539993 — microbiology — Posted on 2023-05-15
2331 Dual control of host actin polymerization by a Legionella effector pair
Pillon, M.; Michard, C.; Baïlo, N.; Bougnon, J.; Picq, K.; Dubois, O.; Andrea, C.; Attaiech, L.; Daubin, V.; Jarraud, S.; Kay, E.; Doublet, P.
10.1101/2023.05.15.540800 — microbiology — Posted on 2023-05-15
2337 Decreasing the flexibility of the TELSAM-target protein linker and omitting the cleavable fusion tag improves crystal order and diffraction limits
Gajjar, P.; Pedroza-Romo, M. J.; Litchfield, C.; Callahan, M.; Redd, N.; Nawarathnage, S. D.; Soleimani, S.; Averett, J.; Wilson, E.; Lewis, A.; Stewart, C.; Tseng, Y. J.; Doukov, T.; Lebedev, A.; Moody, J. D.
10.1101/2023.05.12.540586 — biochemistry — Posted on 2023-05-15
2341 In vivo Ontogeny of human forebrain neural progenitor cell grafts in adult rats: an immunohistological study
Liu, C.; Lin, A.; Xing, Q.; Zhang, D.; Meng, W.; Wu, R.; Shi, H.; Huang, W.; Huang, X.; Qin, D.; Wang, X.; Zhong, X.; Guo, Y.
10.1101/2023.05.15.539796 — cell biology — Posted on 2023-05-15
2342 Surface exclusion of IncC conjugative plasmids and their relatives
Rivard, N.; Humbert, M.; Huguet, K. T.; Perez Bucio, C.; Quirion, E.; Burrus, V.
10.1101/2023.05.15.540745 — microbiology — Posted on 2023-05-15
2343 Revealing the lipidome and proteome of Arabidopsis thaliana plasma membrane
Bahammou, D.; Recorbet, G.; Mamode Cassim, A.; Robert, F.; Balliau, T.; Van Delf, P.; Haddad, Y.; Mounier, A.; Mongrand, S.; Fouillen, L.; Simon-Plas, F.
10.1101/2023.05.14.540643 — plant biology — Posted on 2023-05-15
2346 In vivo screening of tumor-hepatocyte interactions identifies Plexin B2 as a gatekeeper of liver metastasis
Borrelli, C.; Roberts, M.; Eletto, D.; Lafzi, A.; Kretz, J. A.; Fazilaty, H.; Hussherr, M.-D.; Guido Vinzoni, E.; Handler, K.; Michler, J.; Adivarahan, S.; Piscuoglio, S.; Ficht, X.; Moor, A. E.
10.1101/2023.05.15.540681 — cancer biology — Posted on 2023-05-15
2350 The direction of local adaptation on pathogen exploitation rates reverses with environmental context
Visher, E.; Ali, A.; Barajas, J.; Masud, S.; McBride, A.; Ramos, E.; Sui, M.; Villalobos-Heredia, C.; Walzer, N.; White, P. S.; Boots, M.
10.1101/2023.05.12.540593 — evolutionary biology — Posted on 2023-05-15
2351 Alpha-synuclein pre-formed fibrils injected into prefrontal cortex primarily spread to cortical and subcortical structures and lead to isolated behavioral symptoms
Weber, M. A.; Kerr, G.; Thangavel, R.; Conlon, M. M.; Abdelmotilib, H. A.; Halhouli, O.; Zhang, Q.; Geerling, J. C.; Narayanan, N. S.; Aldridge, G. M.
10.1101/2023.01.31.526365 — animal behavior and cognition — Posted on 2023-05-15
2354 Atlas of Plasmodium falciparum intraerythrocytic development using expansion microscopy
Liffner, B.; Cepeda Diaz, A. K.; Blauwkamp, J.; Anaguano, D.; Frolich, S.; Muralidharan, V.; Wilson, D. W.; Dvorin, J.; Absalon, S.
10.1101/2023.03.22.533773 — cell biology — Posted on 2023-05-15
2356 Characterizing endogenous delta oscillations in human MEG
Gunasekaran, H.; Azizi, L.; van Wassenhove, V.; Herbst, S. K.
10.1101/2022.12.15.520554 — neuroscience — Posted on 2023-05-15
2359 Immunosuppression with Cyclosporine versus Tacrolimus shows distinctive nephrotoxicity profiles within renal compartments
Demirci, H.; Popovic, S.; Dittmayer, C.; Yilmaz, D. E.; El-Shimy, I. A.; Mülleder, M.; Hinze, C.; Persson, P. B.; Mutig, K.; Bachmann, S.
10.1101/2023.04.05.535688 — pathology — Posted on 2023-05-15
2360 Sequencing accuracy and systematic errors of nanopore direct RNA sequencing
Liu-Wei, W.; van der Toorn, W.; Bohn, P.; Hölzer, M.; Smyth, R.; von Kleist, M.
10.1101/2023.03.29.534691 — bioinformatics — Posted on 2023-05-15
2361 RawHash: Enabling Fast and Accurate Real-Time Analysis of Raw Nanopore Signals for Large Genomes
Firtina, C.; Ghiasi, N. M.; Lindegger, J.; Singh, G.; Cavlak, M. B.; Mao, H.; Mutlu, O.
10.1101/2023.01.22.525080 — bioinformatics — Posted on 2023-05-15
2362 Novel insights into the cold resistance of Hevea brasiliensis through coexpression networks
Silva, C. C.; Bajay, S. K.; Aono, A. H.; Francisco, F. R.; Junior, R. B.; de Souza, A. P.; Mantello, C. C.; Vicentini dos Santos, R.
10.1101/2021.11.02.466997 — genomics — Posted on 2023-05-15
2363 Nfe2l1-mediated proteasome function controls muscle energy metabolism in obesity
Lemmer, I. L.; Haas, D. T.; Willemsen, N.; Kotschi, S.; Toksoez, I.; Gjika, E.; Khani, S.; Rohm, M.; Diercksen, N.; Nguyen, P. B. H.; Menden, M. P.; Egu, D. T.; Waschke, J.; Larsen, S.; Ma, T.; Gerhart-Hines, Z.; Herzig, S.; Dyar, K.; Krahmer, N.; Bartelt, A.
10.1101/2023.04.20.537611 — physiology — Posted on 2023-05-15
2364 Variation in temperature of peak trait performance will constrain adaptation of arthropod populations to climatic warming.
Pawar, S.; Huxley, P.; Smallwood, T.; Nesbit, M.; Chan, A.; Shocket, M.; Johnson, L. R.; Kontopoulos, D. - G.; Cator, L.
10.1101/2023.01.18.524448 — ecology — Posted on 2023-05-15
2365 Elevated glycolytic metabolism of monocytes limits the generation of HIF-1α-driven migratory dendritic cells in tuberculosis
Maio, M.; Joly, M.; Vahlas, Z.; Barros, J.; Marin Franco, J. L.; Genoula, M.; Monard, S.; Vecchione, M. B.; Fuentes, F.; Gonzalez Polo, V.; Quiroga, M. F.; Vermeulen, M.; Argüello, R. J.; Inwentarz, S.; Musella, R.; Ciallella, L.; Gonzalez Montaner, P.; Palmero, D.; Lugo Villarino, G.; Sasiain, M. d. C.; Neyrolles, O.; Verolle, C.; Balboa, L.
10.1101/2023.04.03.535400 — immunology — Posted on 2023-05-15
2368 Hi-Fi fMRI: High-resolution, fast-sampled and sub-second whole-brain functional MRI at 3T in humans
Franceschiello, B.; Rumac, S.; Hilbert, T.; Nau, M.; Dziadosz, M.; Degano, G.; Roy, C. W.; Gaglianese, A.; Petri, G.; Yerly, J.; Stuber, M.; Kober, T.; van Heeswijk, R. B.; Murray, M. M.; Fornari, E.
10.1101/2023.05.13.540663 — neuroscience — Posted on 2023-05-15
2369 Local gradient analysis of human brain function using the Vogt-Bailey Index
Farrugia, C.; Galdi, P.; Arenzana Irazu, I.; Scerri, K.; Bajada, C. J.
10.1101/2022.10.14.511925 — neuroscience — Posted on 2023-05-15
2372 The adhesion capability of S. aureus cells is heterogeneously distributed over the cell envelope
Spengler, C.; Maikranz, E.; Glatz, B. A.; Klatt, M. A.; Heintz, H.; Bischoff, M.; Santen, L.; Fery, A.; Jacobs, K.
10.1101/2021.01.05.425282 — biophysics — Posted on 2023-05-15
2377 No fitness impact of the knockout of the two main components of mimivirus genomic fiber and fibril layer
Alempic, J.-M.; Bisio, H.; Villalta, A.; Santini, S.; Lartigue, A.; Schmitt, A.; Bugnot, C.; Notaro, A.; BELMUDES, L.; Adrait, A.; Poirot, O.; Ptchelkine, D.; De Castro, C.; Coute, Y.; Abergel, C.
10.1101/2023.04.28.538727 — microbiology — Posted on 2023-05-15
2379 Default Values And Read-Across Proposal For Dermal Absorption Based On Human Skin In Vitro Studies Dataset With Pesticides
Sarti, D. A.; Wagner, J.; Palma, F.; Kalvan, H.; Giachini, M. F.; Lautenschalaeger, D.; Lupianhez, V.; Pires, J. C.; Sales, M.; de Faria, P. M.; Bertomeu, L. C.; Le Bras, M.
10.1101/2023.05.11.540395 — pharmacology and toxicology — Posted on 2023-05-15
2380 Acute irradiation alters the heterogeneity among medullary thymic epithelial cells 2
Horie, K.; Namiki, K.; Miyauchi, M.; Ishikawa, T.; Hayama, M.; Maruyama, Y.; Miyao, T.; Murata, S.; Akiyama, N.; Akiyama, T.
10.1101/2023.04.03.535248 — immunology — Posted on 2023-05-15
2382 Pyrethroid susceptibility reversal in Aedes aegypti: a longitudinal study in Tapachula, Mexico
Saavedra-Rodriguez, K.; Penilla-Navarro, P.; Solis-Santoyo, F.; Lopez-Solis, A.; Rodriguez, A. D.; Vera-Maloof, F.; Lozano, S.; Contreras-Mejia, E.; Vazquez-Samayoa, G.; Perera, R.; Black, W. C.; Torreblanca-Lopez, R.
10.1101/2023.05.11.540334 — evolutionary biology — Posted on 2023-05-15
2383 PROX1 inhibits PDGF-B expression to prevent myxomatous degeneration of heart valves
Ho, Y.-C.; Geng, X.; O'Donnell, A.; Ibarrola, J.; Fernandez-Celis, A.; Varshney, R.; Subramani, K.; Azartash-Namin, Z. J.; Kim, J.; Silasi, R.; Wylie-Sears, J.; Alvandi, Z.; Chen, L.; Cha, B.; Chen, H.; Xia, L.; Zhou, B.; Lupu, F.; Burkhart, H.; Aikawa, E.; Olson, L.; Ahamed, J.; Lopez-Andres, N.; Bischoff, J.; Yutzey, K. E.; Srinivasan, R. S.
10.1101/2023.05.10.540284 — developmental biology — Posted on 2023-05-15
2384 DNA damage primes hematopoietic stem cells for direct megakaryopoiesis
Garyn, C. M.; Bover, O.; Murray, J. W.; Jing, M.; Salas Briceno, K. J.; Ross, S. R.; Snoeck, H.-W.
10.1101/2023.05.13.540665 — cell biology — Posted on 2023-05-15
2385 Engineering Ca2+-dependent DNA polymerase activity
Biggs, B. W.; de Paz, A. M.; Bhan, N. J.; Cybulski, T. R.; Church, G. M.; Tyo, K. E. J.
10.1101/2023.05.11.540423 — synthetic biology — Posted on 2023-05-15
2386 A eukaryote-specific factor mediates an early step in the assembly of plant photosystem II
Armbruster, U.; Keller, J.-M.; Frieboes, M. J.; Jödecke, L.; Kappel, S.; Rindfleisch, T.; Sandoval-Ibanez, O.; Gerlach, I.; Thiele, W.; Bock, R.; Eirich, J.; Finkemeier, I.; Schunemann, D.; Zoschke, R.; Schöttler, M. A.
10.1101/2023.05.12.540541 — plant biology — Posted on 2023-05-15
2392 Hi-Fi fMRI: High-resolution, fast-sampled and sub-second whole-brain functional MRI at 3T in humans
Franceschiello, B.; Rumac, S.; Hilbert, T.; Nau, M.; Dziadosz, M.; Degano, G.; Roy, C. W.; Gaglianese, A.; Petri, G.; Yerly, J.; Stuber, M.; Kober, T.; van Heeswijk, R. B.; Murray, M. M.; Fornari, E.
10.1101/2023.05.13.540663 — neuroscience — Posted on 2023-05-15
2393 Development of compact transcriptional effectors using high-throughput measurements in diverse contexts
Tycko, J.; Van, M.; Aradhana, ; DelRosso, N.; Yao, D.; Xu, X.; Ludwig, C.; Spees, K.; Liu, K.; Hess, G. T.; Gu, M.; Mukund, A. X.; Suzuki, P. H.; Kamber, R. A.; Qi, L. S.; Bintu, L.; Bassik, M. C.
10.1101/2023.05.12.540558 — systems biology — Posted on 2023-05-14
2394 Sex-dependent Differences in the Genomic Profile of Lingual Sensory Neurons in Naive and Tongue-Tumor Bearing Mice
Ibrahim, T.; Wu, P.; Wang, L.-J.; Fang-Mei, C.; Murillo, J.; Merlo, J.; Tumanov, A.; Lai, Z.; Weldon, K.; Chen, Y.; Ruparel, S.
10.1101/2023.01.14.524011 — neuroscience — Posted on 2023-05-14
2395 Sleep-insomnia superposition: opposing brain signatures of sleep in task-based and resting-state conditions
Abdelhack, M.; Zhukovsky, P.; Milic, M.; Harita, S.; Griffiths, J. D.; Hill, S. L.; Felsky, D.
10.1101/2023.05.13.540646 — neuroscience — Posted on 2023-05-14
2397 Tumor-derived biomarkers beyond antigen expression enhance efficacy of CD276/B7H3 antibody-drug conjugate in metastatic prostate cancer
Agarwal, S.; Fang, L.; McGowen, K.; Yin, J.; Bowman, J.; Alilin, A. N.; Ku, A. T.; Corey, E.; Roudier, M.; True, L.; Dumpit, R.; Coleman, I.; Lee, J.; Nelson, P. S.; Capaldo, B. J.; Mariani, A.; Hoover, C.; Senatorov, I. S.; Beshiri, M.; Sowalsky, A. G.; Hurt, E. M.; Kelly, K.
10.1101/2022.04.19.488784 — cancer biology — Posted on 2023-05-14
2399 Regulation of shelterin proteins TERF2IP and TRF2 by H3K4me3-p65 axis drives hyperglycemia dependent endothelial senescence
Thakar, S.; Bhattacharya, R.; Katakia, Y. T.; Chakraborty, S.; Ramakrishnan, S.; Thakkar, N. P.; Dey, S.; Chowdhury, S.; Majumder, S.
10.1101/2023.05.12.540614 — biochemistry — Posted on 2023-05-14
2401 Predicting predator-prey interactions in terrestrial endotherms using random forest
Llewelyn, J.; Strona, G.; Dickman, C. R.; Greenville, A.; Wardle, G.; Lee, M. S. Y.; Doherty, S.; Shabani, F.; Saltre, F.; Bradshaw, C. J. A.
10.1101/2022.09.02.506446 — ecology — Posted on 2023-05-14
2402 Domain loss enabled evolution of novel functions in a gene superfamily
Koludarov, I.; Senoner, T.; Jackson, T. N. W.; Dashevsky, D.; Heinzinger, M.; Aird, S. D.; Rost, B.
10.1101/2022.12.15.520616 — molecular biology — Posted on 2023-05-14
2405 Genome-wide CRISPRi knockdown to map gene essentiality landscape in coliphages {lambda} and P1
Piya, D.; Nolan, N.; Moore, M. L.; Ramirez Hernandez, L. A.; Cress, B. F.; Young, R.; Arkin, A. P.; Mutalik, V. K.
10.1101/2023.05.14.540688 — microbiology — Posted on 2023-05-14
2406 Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-associated mutations
Hussein, Y.; Tripathi, U.; Choudhary, A.; Nayak, R.; Peles, D.; Rosh, I.; Rabinski, T.; Djamus, J.; Vatine, G.; Spiegel, R.; Garin-Shkolnik, T.; Stern, S.
10.1101/2022.11.02.514882 — neuroscience — Posted on 2023-05-14
2408 A Drosophila glial cell atlas reveals a mismatch between detectable transcriptional diversity and morphological diversity
Lago-Baldaia, I.; Cooper, M.; Seroka, A. P.; Trivedi, C.; Powell, G. T.; Wilson, S. W.; Ackerman, S. D.; Fernandes, V. M.
10.1101/2022.08.01.502305 — neuroscience — Posted on 2023-05-14
2409 Transcriptomic profiling of reward and sensory brain areas in perinatal fentanyl exposed juvenile mice
Olusakin, J.; Kumar, G.; Basu, M.; Calarco, C. A.; Fox, M. E.; Alipio, J. B.; Haga, C.; Turner, M. D.; Keller, A.; Ament, S. A.; Lobo, M. K.
10.1101/2022.11.18.517129 — neuroscience — Posted on 2023-05-14
2410 Cardiac competence of the paraxial head mesoderm fades concomitant with a shift towards the head skeletal muscle programme
Alzamrooni, A. M. A. M.; Mendes Vieira, P. J.; Murciano, N.; Wolton, M.; Schubert, F. R.; Robson, S. C.; Dietrich, S.
10.1101/759506 — developmental biology — Posted on 2023-05-14
2413 Synaptic and dendritic architecture of two types of hippocampal somatostatin interneurons
Takacs, V.; Bardoczi, Z.; Orosz, A.; Major, A.; Tar, L.; Berki, P.; Papp, P.; Mayer, M. I.; Zsolt, L.; Sos, K. E.; Kali, S.; Freund, T. F.; Nyiri, G.
10.1101/2023.05.14.540675 — neuroscience — Posted on 2023-05-14
2414 Transcriptomic Evaluation of Stress Vulnerability Network using Single Cell RNA-Seq in mouse Prefrontal Cortex
Hing, B.; Mitchell, S. B.; Eberle, M.; Filali, Y.; Matkovich, M.; Kasturirangan, M.; Hultman, I.; Wyche, W.; Jimenez, A.; Velamuri, R.; Johnson, M.; Srivastava, S.; Hultman, R.
10.1101/2023.05.14.540705 — neuroscience — Posted on 2023-05-14
2419 Mapping the functional impact of non-coding regulatory elements in primary T cells through single-cell CRISPR screens
Alda-Catalinas, C.; Ibarra-Soria, X.; Flouri, C.; Esparza-Gordillo, J.; Cousminer, D.; Hutchinson, A.; Krejci, A.; Cortes, A.; Acevedo, A.; Malla, S.; Fishwick, C.; Drewes, G.; Rapiteanu, R.
10.1101/2023.05.14.540711 — genomics — Posted on 2023-05-14
2422 Diving efficiency at depth and pre-breeding foraging effort increase with hemoglobin levels in gentoo penguins
McComb-Turbitt, S. P.; Crossin, G. T.; Tierney, M.; Brickle, P.; Trathan, P.; Williams, T.; Auger-Methe, M.
10.1101/2023.05.14.539907 — ecology — Posted on 2023-05-14
2424 ADBP-1 regulates ADR-2 nuclear localization to control editing substrate selection
Eliad, B.; Schneider, N.; Ben-Naim Zgayer, O.; Amichan, Y.; Erdmann, E. A.; Hundley, H. A.; Lamm, A.
10.1101/2023.05.14.540679 — cell biology — Posted on 2023-05-14
2426 Allochthonous groundwater microorganisms affect coastal seawater microbial abundance, activity and diversity
Yanuka-Golub, K.; Belkin, N.; Weber, N.; Mayyani, M.; Levy, Y.; Reznik, I. J.; Rubin-Blum, M.; Rahav, E.; Kiro, Y.
10.1101/2023.05.14.540660 — microbiology — Posted on 2023-05-14
2427 Genome-wide CRISPRi knockdown to map gene essentiality landscape in coliphages {lambda} and P1
Mutalik, V. K.; Piya, D.; Nolan, N.; Moore, M. L.; Ramirez Hernandez, L. A.; Cress, B. F.; Young, R.; Arkin, A. P.
10.1101/2023.05.14.540688 — microbiology — Posted on 2023-05-14
2428 Early cellular and molecular signatures correlate with severity of West Nile Virus infection
Lee, H.-J.; Zhao, Y.; Fleming, I.; Mehta, S.; Wang, X.; Vander Wyk, B.; Ronca, S. E.; Kang, H.; Chou, C.-H.; Fatou, B.; Smolen, K. K.; Levy, O.; Clish, C. B.; Xavier, R. J.; Steen, H.; Hafler, D. A.; Love, J. C.; Shalek, A. K.; Guan, L.; Murray, K. O.; Kleinstein, S. H.; Montgomery, R. R.
10.1101/2023.05.14.540642 — immunology — Posted on 2023-05-14
2430 Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models
Martinez, A.; Sanchez-Martinez, A.; Pickering, J. T.; Twyning, M. J.; Terriente-Felix, A.; Chen, P.-L.; CHEN, C.-H.; Whitworth, A. J.
10.1101/2023.05.14.540700 — neuroscience — Posted on 2023-05-14
2431 Inhibition of LRRK2 kinase activity rescues deficits in striatal dopamine dynamics in VPS35 p.D620N knock-in mice
Bu, M.; Follett, J.; Tatarnikov, I.; Wall, S. C.; Guenther, D. T.; Deng, I. B.; Wimsatt, G.; Milnerwood, A.; Moehle, M.; Khoshbouei, H.; Farrer, M. J.
10.1101/2023.05.14.540654 — neuroscience — Posted on 2023-05-14
2437 STimage:robust, confident and interpretable models for predicting gene markers from cancer histopathological images
Tan, X.; Mulay, O.; MacDonald, S.; Kim, T.; Werry, J.; Simpson, P. T.; Roosta, F.; Trzaskowski, M.; Nguyen, Q.
10.1101/2023.05.14.540710 — bioinformatics — Posted on 2023-05-14
2442 P-tau Inflicts Intracellular Stress Responses That Are Mitigated by Apomorphine
Song, Z.; Wang, K.-W.; Hagar, H.-T. C.; Chen, H.-R.; Kuan, C.-Y.; Zhang, K.; Kuo, M.-H.
10.1101/2023.05.13.540661 — biochemistry — Posted on 2023-05-14
2444 The Loss of the H1.4 Linker Histone Impacts Nascent Transcription and Chromatin Accessibility
Gokey, N. G.; Ward, J. M.; Milliman, E. J.; Deterding, L. J.; Trotter, K. W.; Archer, T. K.
10.1101/2023.05.14.540702 — genomics — Posted on 2023-05-14
2445 Extensive Copy Number Variation Explains Genome Size Variation in the Unicellular Zygnematophycean Alga, Closterium peracerosum-strigosum-littorale Complex
Kawaguchi, Y. W.; Tsuchikane, Y.; Tanaka, K.; Taji, T.; Suzuki, Y.; Toyoda, A.; Ito, M.; Watano, Y.; Nishiyama, T.; Sekimoto, H.; Tsuchimatsu, T.
10.1101/2023.05.13.540557 — evolutionary biology — Posted on 2023-05-14
2448 Global substrate identification and high throughput in vitro dephosphorylation reactions uncover PP1 and PP2A-B55 specificity principles
Hein, J. B.; Nguyen, H. T.; Garvanska, D.; Nasa, I.; Feng, Y.; Lopez-Mendez, B.; Davey, N. E.; Kettenbach, A.; Fordyce, P. M.; Nilsson, J.
10.1101/2023.05.14.540683 — cell biology — Posted on 2023-05-14
2451 Warming During Embryogenesis Induces a Lasting Transcriptomic Signature in Fishes
Ripley, D. M.; Garner, T.; Hook, S. A.; Verissimo, A.; Grunow, B.; Moritz, T.; Clayton, P.; Shiels, H. A.; Stevens, A.
10.1101/2021.12.07.470713 — developmental biology — Posted on 2023-05-14
2459 Sleep-insomnia superposition: opposing brain signatures of sleep in task-based and resting-state conditions
Abdelhack, M.; Zhukovsky, P.; Milic, M.; Harita, S.; Griffiths, J. D.; Hill, S. L.; Felsky, D.
10.1101/2023.05.13.540646 — neuroscience — Posted on 2023-05-14
2460 Invariant neural dynamics drive commands to control different movements
Athalye, V. R.; Khanna, P.; Gowda, S.; Orsborn, A. L.; Costa, R. M.; Carmena, J. M.
10.1101/2021.08.27.457931 — neuroscience — Posted on 2023-05-14
2463 Defining Mitochondrial Cristae Morphology Changes Induced by Aging in Brown Adipose Tissue
Crabtree, A.; Neikirk, K.; Marshall, A.; Vang, L.; Stephens, D.; Shao, B.; Garza-Lopez, E.; Lam, J.; Rodriguez, B.; Mungai, M.; Stanley, J.; Dean, D.; Gaddy, J.; Scudese, E.; Sweetwyne, M.; Davis, J.; Zaganjor, E.; Murray, S.; Katti, P.; Damo, S.; Vue, Z.; Hinton, A.
10.1101/2023.05.12.540609 — biophysics — Posted on 2023-05-14
2465 Towards Computing Attributions for DimensionalityReduction Techniques
Scicluna, M. C.; Grenier, J.-C.; Poujol, R.; Lemieux, S.; Hussin, J.
10.1101/2023.05.12.540592 — bioinformatics — Posted on 2023-05-14
2466 Resolving the unsolved: Comprehensive assessment of tandem repeats at scale
Dolzhenko, E.; English, A.; Dashnow, H.; De Sena Brandine, G.; Mokveld, T.; Rowell, W. J.; Karniski, C.; Kronenberg, Z.; Danzi, M. C.; Cheung, W. A.; Bi, C.; Farrow, E.; Wenger, A.; Martinez-Cerdeno, V.; Bartley, T. D.; Jin, P.; Nelson, D.; Zuchner, S.; Pastinen, T.; Quinlan, A. R.; Sedlazeck, F. J.; Eberle, M. A.
10.1101/2023.05.12.540470 — genomics — Posted on 2023-05-14
2467 Giants among Cnidaria: large nuclear genomes and rearranged mitochondrial genomes in siphonophores
Ahuja, N.; Cao, X.; Schultz, D. T.; Picciani, N.; Lord, A.; Shao, S.; Burdick, D. R.; Haddock, S. H. D.; Li, Y.; Dunn, C. W.
10.1101/2023.05.12.540511 — evolutionary biology — Posted on 2023-05-14
2470 The role of structural vs cellular remodeling in arrhythmogenesis: personalized computer models of atrial fibrillation.
Pikunov, A. V.; Syunyaev, R. A.; Ali, R.; Prakosa, A.; Boyle, P. M.; Steckmeister, V.; Kutschka, I.; Rytkin, E.; Voigt, N.; Trayanova, N.; Efimov, I. R.
10.1101/2023.05.13.540632 — physiology — Posted on 2023-05-14
2471 The androgen receptor does not directly regulate the transcription of DNA damage response genes
Hasterok, S.; Scott, T. G.; Roller, D. G.; Spencer, A.; Dutta, A. B.; Sathyan, K. M.; Frigo, D. E.; Guertin, M. J.; Gioeli, D.
10.1101/2023.05.13.540653 — cancer biology — Posted on 2023-05-14
2474 REPIC -- an ensemble learning methodology for cryo-EM particle picking
Cameron, C. J.; Seager, S. J.; Sigworth, F. J.; Tagare, H. D.; Gerstein, M. B.
10.1101/2023.05.13.540636 — bioinformatics — Posted on 2023-05-14
2475 MethPhaser: methylation-based haplotype phasing of human genomes
Fu, Y.; Aganezov, S.; Mahmoud, M.; Beaulaurier, J.; Juul, S.; Treangen, T. J.; Sedlazeck, F. J.
10.1101/2023.05.12.540573 — bioinformatics — Posted on 2023-05-14
2478 Quantitative flow cytometric selection of tau conformational nanobodies specific for pathological aggregates
Zupancic, J. M.; Smith, M. D.; Trzeciakiewicz, H.; Skinner, M. E.; Ferris, S. P.; Makowski, E. K.; Lucas, M. J.; McArthur, N.; Kane, R. S.; Paulson, H. L.; Tessier, P. M.
10.1101/2023.05.13.540640 — bioengineering — Posted on 2023-05-14
2479 Genomic epidemiology of Treponema pallidum and circulation of strains with diminished tprK antigen variation capability in Seattle, 2021-2022
Lieberman, N. A.; Avendano, C.; Mohamed Bakhash, S. A.; Nunley, E.; Xie, H.; Giacani, L.; Berzkalns, A.; Soge, O. O.; Reid, T. B.; Golden, M. R.; Greninger, A. L.
10.1101/2023.05.12.540601 — genomics — Posted on 2023-05-14
2480 Multiplex PCR detection and Nanopore-based rapid genotyping of tilapia (Oreochromis spp.) pathogens.
Delamare-Deboutteville, J.; Meetmetta, W.; Pimsannil, K.; Gan, H. M.; Kayansamruaj, P.; Khor Li Imm, L.; Chadag Mohan, V.; Dong, H. T.; Senapin, S.
10.1101/2023.05.13.540096 — genomics — Posted on 2023-05-14
2481 Resolving genotype-phenotype discrepancies of the Kidd blood group using nanopore sequencing
Gueuning, M.; Thun, G. A.; Schneider, L.; Trost, N.; Sigurdardottir, S.; Engström, C.; Rizzi, G.; Merki, Y.; Neuenschwander, K.; Frey, B. M.; Mattle-Greminger, M. P.; Meyer, S.
10.1101/2023.05.13.540649 — genetics — Posted on 2023-05-14
2482 Models to Estimate Genetic Gain of Soybean Seed Yield from Annual Multi-Environment Field Trials
Dalsente Krause, M.; Piepho, H.-P.; Dias Olimpio das Gracas, K.; Singh, A. K.; Beavis, W. D.
10.1101/2023.05.13.540664 — genetics — Posted on 2023-05-14
2484 Influence of oceanography and geographic distance on genetic structure: how varying the sampled domain influences conclusions in Laminaria digitata
Fouqueau, L.; Reynes, L.; Tempera, F.; Bajjouk, T.; Blanfune-Thibaut, A.; Chevalier, C.; Laurans, M.; Mauger, S.; Sourisseau, M.; Assis, J.; Leveque, L.; Valero, M.
10.1101/2023.05.11.540379 — evolutionary biology — Posted on 2023-05-14
2487 Spatial connectivity increases ecosystem resilience towards an ongoing regime shift
Olin, A. B.; Bergström, U.; Bodin, O.; Sundblad, G.; Eriksson, B. K.; Erlandsson, M.; Fredriksson, R.; Eklöf, J.
10.1101/2023.05.12.540484 — ecology — Posted on 2023-05-14
2489 Tectonic Complex Impedes Diffusion through the Ciliary Transition Zone to Ensure Proper Sorting of Membrane Proteins
Truong, H. M.; Cruz-Colon, K. O.; Martinez-Marquez, J. Y.; Willer, J. R.; Travis, A. M.; Biswas, S. K.; Lo, W.-K.; Bolz, H. J.; Pearring, J. N.
10.1101/2023.05.13.540647 — cell biology — Posted on 2023-05-14
2490 Skp1 proteins are structural components of the synaptonemal complex in C. elegans
Blundon, J.; Cesar, B.; Bae, J. W.; Cavka, I.; Haversat, J.; Ries, J.; Koehler, S.; Kim, Y.
10.1101/2023.05.13.540652 — cell biology — Posted on 2023-05-14
2492 A Hydroponic-Based Bioassay to Facilitate Plasmodiophora brassicae Phenotyping
Salih, R.; Brochu, A.-S.; Labbe, C.; Strelkov, S.; Franke, C.; Belanger, R.; Perez-Lopez, E.
10.1101/2023.05.13.540618 — microbiology — Posted on 2023-05-14
2493 Peripheral serotonergic neurons regulate anxiety-like behavior and intestinal barrier immunity
Waldor, M. K.; Zhang, H.; Hasegawa, Y.; Leitner, D.; Zhang, T.; Suzuki, M.; Jackson, R.
10.1101/2023.05.12.540588 — immunology — Posted on 2023-05-14
2494 Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326)
Ferguson, M.; Delgado, K. N.; McBride, S.; Orbe, I. C.; LaVake, C. J.; Caimano, M. J.; Mendez, Q.; Moraes, T. F.; Schryvers, A. B.; Moody, M. A.; Radolf, J. D.; Weiner, M.; Hawley, K. L.
10.1101/2023.05.13.540667 — immunology — Posted on 2023-05-14
2495 NAIP-NLRC4 Inflammasome Activation in Tuft Cells Activates a PGD2-ILC3 Signaling Circuit that Protects Against Enteric Infection.
Churchill, M. J.; Bauer, R.; Honodel, R.; Christopher, T.; Smita, S.; Warner, L.; Mooney, B. M.; Wojno, E. D. T.; Rauch, I.
10.1101/2023.05.11.540443 — immunology — Posted on 2023-05-14
2501 Pichia pastoris growth - coupled heme biosynthesis analysis using metabolic modelling
Pentjuss, A.; Bolmanis, E.; Suleiko, A.; Didrihsone, E.; Suleiko, A.; Dubencovs, K.; Liepins, J.; Kazaks, A.; Vanags, J.
10.1101/2023.05.13.540629 — systems biology — Posted on 2023-05-14
2502 A framework for ultra-low input spatial tissue proteomics
Makhmut, A.; Qin, D.; Fritzsche, S.; Nimo, J.; Koenig, J.; Coscia, F.
10.1101/2023.05.13.540426 — systems biology — Posted on 2023-05-14
2504 Pregnancy and postpartum dynamics revealed by an atlas of millions of lab tests
Bar, A.; Mendelson Cohen, N.; Korem Kohanim, Y.; Mayo, A.; Toledano, Y.; Alon, U.
10.1101/2023.05.11.540359 — physiology — Posted on 2023-05-14
2505 Paneth and Paneth-like cells undergoing necroptosis fuel intestinal epithelial cell proliferation following IFN-γ stimulation.
Nava, P.; Encarnacion-Garcia, M. R.; De la Torre-Baez, R.; Hernandez-Cueto, M. A.; Velazquez-Villegas, L. A.; Candelario-Martinez, A.; Horta-Lopez, P. H.; Montoya-Garcia, A.; Jaimes-Ortega, G. A.; Lopez-Bailon, L.; Piedra-Quintero, Z.; Carrasco-Torres, G.; De Ita, M.; Figueroa-Corona, M. d. P.; Munoz-Medina, J. E.; Sanchez-Uribe, M.; Meraz-Rios, M. A.; Villa-Trevino, S.; Garcia-Sierra, F.; Cisneros, B.; Schnoor, M.; Ortiz-Navarrete, V. F.; Villegas-Sepulveda, N.; Valle-Rios, R.; Medina-Contreras, O.; Noriega, L. G.
10.1101/2023.05.13.540666 — physiology — Posted on 2023-05-14
2507 Targeted inhibition of SCF-SKP2 confers anti-tumor activities resulting in a survival benefit in osteosarcoma
Wang, J.; Ferrena, A.; Singh, S.; Viscarret, V.; Al-Hardan, W.; Aldahamsheh, O.; Borjihan, H.; Singla, A.; Yaguare, S.; Tingling, J.; Zi, X.; Lo, Y.; Gorlick, R.; Schwartz, E. L.; Zhao, H.; Yang, R.; Geller, D. S.; Zheng, D.; Hoang, B. H.
10.1101/2023.05.13.540637 — cancer biology — Posted on 2023-05-14
2508 In depth profiling of the cancer proteome from the flowthrough of standard RNA-preparation kits for precision oncology
Mundt, F.; Nielsen, A. B.; Duel, J. K.; Yde, C. W.; Eriksen, M. A.; Lassen, U.; Nielsen, F. C.; Rohrberg, K.; Mann, M.
10.1101/2023.05.12.540582 — cancer biology — Posted on 2023-05-14
2509 RIP140 regulates HES1 oscillatory expression and mitogenic activity in colon cancer cells
Sfeir, N.; Kajdan, M.; Jalaguier, S.; Bonnet, S.; Teyssier, C.; Pyrdziak, S.; Yuan, R.; Bousquet, E.; Maraver, A.; Bernex, F.; Pirot, N.; Boissiere, F.; Castet-Nicolas, A.; Lapierre, M.; Cavailles, V.
10.1101/2023.05.13.539637 — cancer biology — Posted on 2023-05-14
2511 Cardiac Effects of a Novel pH-Insensitive Sodium-Calcium Exchanger Mouse
Zhang, R.; Wu, X.; Kim, B.; Xie, C.; Gonzalez, D.; Norris, R.; Chin, N.; Li, L.; John, S.; Philipson, K.; Ottolia, M.; Goldhaber, J. I.
10.1101/2023.05.11.540465 — biophysics — Posted on 2023-05-14
2518 Drug Repositioning using Consilience of Knowledge Graph Completion Methods
Tu, R.; Sinha, M.; Gonzalez-Cavazos, A. C.; Hu, E.; Dhuliawala, S. Z.; McCallum, A.; Su, A. I.
10.1101/2023.05.12.540594 — bioinformatics — Posted on 2023-05-14
2519 AnnoPRO: an innovative strategy for protein function annotation based on image-like protein representation and multimodal deep learning
Zheng, L.; Shi, S.; Fang, P.; Zhang, H.; Pan, Z.; Huang, S.; Xia, W.; Li, H.; Zeng, Z.; Zhang, S.; Chen, Y.; Lu, M.; Li, Z.; Zhu, F.
10.1101/2023.05.13.540619 — bioinformatics — Posted on 2023-05-14
2520 The Computational Analysis of Plasmodium falciparum Heat Shock Proteins Reveals an Interplay with Polyamines
Makhoba, X. H.; Godlo, S.; Maxam, N.; Mthembu, Y.; Mpumza, A.; Makumire, S.; Mkwetshana, N.; Govender, K. K.
10.1101/2023.05.11.540332 — bioinformatics — Posted on 2023-05-14
2522 Towards substitution of invasive telemetry: An integrated home cage concept for unobstrusive monitoring of objective physiological parameters in rodents
Mösch, L.; Kunzcik, J. F.; Breuer, L.; Merhof, D.; Gass, P.; Potschka, H.; Zechner, D.; Vollmar, B.; Tolba, R.; Häger, C.; Bleich, A.; Czaplik, M.; Pereira, C. B.
10.1101/2023.05.12.540546 — bioengineering — Posted on 2023-05-14
2524 Systemic evaluation of protein-small molecule hybrids on the yeast surface
Huang, M.; Rueda-Garcia, M.; Harthorn, A.; Hackel, B. J.; Van Deventer, J. A.
10.1101/2023.05.12.540568 — bioengineering — Posted on 2023-05-14
2526 A common flanking variant is associated with enhanced meiotic stability of the FGF14-SCA27B locus
Pellerin, D.; Del Gobbo, G.; Couse, M.; Dolzhenko, E.; Dicaire, M.-J.; Rebelo, A.; Roth, V.; Wandzel, M.; Bonnet, C.; Ashton, C.; Lamont, P. J.; Laing, N. G.; Renaud, M.; Ravenscroft, G.; Houlden, H.; Synofzik, M.; Eberle, M. A.; Boycott, K. M.; Pastinen, T.; Brais, B.; Zuchner, S.; Danzi, M. C.
10.1101/2023.05.11.540430 — genetics — Posted on 2023-05-14
2528 Primary nasal viral infection rewires the tissue-scale memory response
Kazer, S. W.; Match, C. M.; Langan, E. M.; LaSalle, T. J.; Marbourg, J.; Naughton, K.; O'Leary, E.; von Andrian, U. H.; Ordovas-Montanes, J.
10.1101/2023.05.11.539887 — immunology — Posted on 2023-05-14
2529 Co-engagement of TIGIT+ immune cells to PD-L1+ tumours by a bispecific antibody potentiates T-cell response and tumour control
Cui, X.; Yu, H.; Zhu, X.; Xu, J.; Wei, X.; Chen, S.; Wang, Y.; Chen, X.; Feng, Y.; Ren, X.; Fei, L.; Xie, B.; Li, M.; Li, X.; Jia, H.; Xie, S.; Chen, L.; Cheng, Y.; Zhang, L.; Li, H.; Zhu, X.; Zhan, Y.
10.1101/2023.05.11.540461 — immunology — Posted on 2023-05-14
2530 An ex vivo model of interactions between extracellular vesicles and peripheral mononuclear blood cells in whole blood
Rodriguez, B. V.; Wen, Y.; Shirk, E. N.; Vazquez, S.; Gololobova, O.; Maxwell, A.; Plunkard, J.; Castell, N. V.; Carlson, B.; Queen, S. E.; Izzi, J. M.; Driedonks, T. A. P.; Witwer, K. W.
10.1101/2023.05.11.540421 — immunology — Posted on 2023-05-14
2531 Macrophage innate immune gene expression requires dynamic regulation of the nuclear paraspeckle
Azam, S.; Armijo, K. S.; Weindel, C. G.; Devigne, A.; Nakagawa, S.; Hirose, T.; Carpenter, S. L.; Watson, R. O.; Patrick, K. L.
10.1101/2023.05.11.540384 — immunology — Posted on 2023-05-14
2532 Coordinated Chemokine Expression Defines Macrophage Subsets Across Tissues
Li, X.; Mara, A. B.; Musial, S.; Rawat, K.; King, W. T.; Kolling, F. W.; Gerebtsov, N.; Jakubzick, C. V.
10.1101/2023.05.12.540435 — immunology — Posted on 2023-05-14
2533 Late- life shift in caloric intake affects fly longevity and metabolism
Li, M.; Macro, J.; Meadows, K.; Mishra, D.; Martin, D.; Olson, S.; Huggins, B. J.; Graveley, B.; Li, J. Y. H.; Rogina, B.
10.1101/2023.05.11.540262 — physiology — Posted on 2023-05-14
2534 SEPTIN 7 INTERACTS WITH NUMB TO PRESERVE SARCOMERE STRUCTURAL ORGANIZATION AND MUSCLE CONTRACTILE FUNCTION.
De Gasperi, R.; Csernoch, L.; Dienes, B.; Gonczi, M.; Chakrabarty, J. K.; Goeta, S.; Aslan, A.; Toro, C. A.; Karasik, D.; Brown, L. M.; Brotto, M.; Cardozo, C. P.
10.1101/2023.05.11.540467 — physiology — Posted on 2023-05-14
2535 NRF2 activation in the heart induces glucose metabolic reprogramming and mediates cardioprotection via upregulation of the pentose phosphate pathway.
Zoccarato, A.; Smyrnias, I.; Reumiller, C. M.; Hafstad, A. D.; Chong, M.; Richards, D. A.; Santos, C. X.; Visnagri, A.; Bromage, D. I.; Zhang, X.; Sawyer, G.; Thompson, R.; Shah, A. M.
10.1101/2023.05.12.540342 — physiology — Posted on 2023-05-14
2536 Default Values And Read-Across Proposal For Dermal Absorption Based On Human Skin In Vitro Studies Dataset With Pesticides
Sarti, D. A.; Wagner, J.; Palma, F.; Kalvan, H.; Giachini, M. F.; Lautenschalaeger, D.; Lupianhez, V.; Pires, J. C.; Sales, M.; de Faria, P. M.; Bertomeu, L. C.; Le Bras, M.
10.1101/2023.05.11.540395 — pharmacology and toxicology — Posted on 2023-05-14
2540 Serialized On-grid Lift-In Sectioning for Tomography (SOLIST)
Erdmann, P. S.; Nguyen, T.-D. H.; Perone, G.; Vazzana, R.; Don, F. K.; Silva, M.; Sorrentino, S.; Swuec, P.; Leroux, F.; Kalebic, N.; Coscia, F.
10.1101/2023.05.11.540146 — biophysics — Posted on 2023-05-14
2541 Foldy: a web application for interactive protein structure analysis
Roberts, J. B.; Nava, A. A.; Pearson, A. N.; Incha, M. R.; Valencia, L. E.; Ma, M.; Rao, A.; Keasling, J. D.
10.1101/2023.05.11.540333 — bioinformatics — Posted on 2023-05-14
2547 Deep learning for rapid and reproducible histology scoring of lung injury in a porcine model
Neves Da Silva, I. A.; Kazemi Rashed, S.; Hedlund, L.; Lidfeldt, A.; Gvazava, N.; Stegmayr, J.; Skoryk, V.; Aits, S.; Wagner, D. E.
10.1101/2023.05.12.540340 — bioinformatics — Posted on 2023-05-14
2551 txci-ATAC-seq, a massive-scale single-cell technique to profile chromatin accessibility
Zhang, H.; Mulqueen, R. M.; Iannuzo, N.; Farrera, D. O.; Polverino, F.; Galligan, J. J.; Ledford, J. G.; Adey, A. C.; Cusanovich, D. A.
10.1101/2023.05.11.540245 — genomics — Posted on 2023-05-14
2552 SMYD5 is a novel epigenetic gatekeeper of the mild hypothermia response
Rafnsdottir, S.; Jang, K.; Halldorsdottir, S. T.; Tomasdottir, A.; Vinod, M.; Moller, K.; Reynisdottir, T.; Atladottir, L. H.; Allison, K. E.; He, J.; Zhang, L.; Northington, F. J.; Chavez-Valdez, R.; Anderson, K. J.; Bjornsson, H.
10.1101/2023.05.11.540170 — genetics — Posted on 2023-05-14
2553 Whole Transcriptome and Functional Analyses Identify Novel Genes Involved in Meiosis and Fertility in Drosophila melanogaster
Sun, S.; Defosse, T.; Boyd, A.; Sop, J.; Verderose, F.; Surray, D.; Aziz, M.; Howland, M.; Wu, S.; Changela, N.; Jang, J.; Schindler, K.; Xing, J.; McKim, K.
10.1101/2023.05.12.540472 — genetics — Posted on 2023-05-14
2555 Chromosome evolution in Lepidoptera
Wright, C. J.; Stevens, L.; Mackintosh, A.; Lawniczak, M.; Blaxter, M.
10.1101/2023.05.12.540473 — evolutionary biology — Posted on 2023-05-14
2559 Initiation phase cellular reprogramming ameliorates DNA damage in the ERCC1 mouse model of premature aging.
Paine, P. T.; Rechsteiner, C.; Morandini, F.; Desdin Mico, G.; Mrabti, C.; Parras, A.; Haghani, A.; Brooke, R.; Horvath, S.; Seluanov, A.; Gorbunova, V.; Ocampo, A.
10.1101/2023.05.12.540500 — cell biology — Posted on 2023-05-14
2560 Diet-induced obesity dysregulates chromatin oxygen sensing regulating efferocytosis in macrophages
Takahashi, K.; Liu, J.; Jackson, J. R.; Thiruppathi, M.; Benevolenskaya, E. V.; Koh, T. J.; Urao, N.
10.1101/2023.05.12.540252 — cell biology — Posted on 2023-05-14
2561 Towards a human brain EV atlas: Characteristics of EVs from different brain regions, including small RNA and protein profiles
Huang, Y.; Arab, T.; Russell, A. E.; Mallick, E. R.; Nagaraj, R.; Gizzie, E.; Redding-Ochoa, J.; Troncoso, J. C.; Pletnikova, O.; Turchinovich, A.; Routenberg, D. A.; Witwer, K. W.
10.1101/2023.05.06.539665 — neuroscience — Posted on 2023-05-14
2563 The conserved protein CBA1 is required for vitamin B12 uptake in different algal lineages
Sayer, A. P.; Llavero-Pasquina, M.; Geisler, K.; Holzer, A.; Bunbury, F.; Mendoza-Ochoa, G. I.; Lawrence, A.; Warren, M. J.; Mehrshahi, P.; Smith, A. G.
10.1101/2023.03.24.534157 — biochemistry — Posted on 2023-05-14
2564 Structural basis and functional roles for Toll-like receptor binding to Latrophilin adhesion-GPCR in embryo development
Carmona-Rosas, G.; Li, J.; Smith, J. J.; Cheng, S.; Baltrusaitis, E.; Nawrocka, W. I.; Zhao, M.; Kratsios, P.; Arac, D.; Özkan, E.
10.1101/2023.05.04.539414 — biochemistry — Posted on 2023-05-14
2565 Characterizing the microbial metagenome of calcareous stromatolite formations in the San Felipe Creek in Anza Borrego Desert
Stancheva, R.; Sethuraman, A.; Khadivar, H.; Archambeau, J.; Caughran, E.; Chang, A.; Hunter, B.; Ihenyen, C.; Onwukwe, M.; Palacios, D.; La Prairie, C.; Read, N.; Tsang, J.; Vega, B.; Velasquez, C.; Zhang, X.; Becket, E.; Read, B.
10.1101/2023.05.12.540589 — genomics — Posted on 2023-05-13
2569 Early warning signals are hampered by a lack of critical transitions in empirical lake data
O'Brien, D. A.; Deb, S.; Gal, G.; Thackeray, S. J.; Dutta, P. S.; Matsuzaki, S.-i. S.; May, L.; Clements, C. F.
10.1101/2023.05.11.540304 — ecology — Posted on 2023-05-13
2570 Highly pathogenic avian influenza causes mass mortality in Sandwich tern (Thalasseus sandvicensis) breeding colonies across northwestern Europe
Knief, U.; Bregnballe, T.; Alfarwi, I.; Ballmann, M.; Brenninkmeijer, A.; Bzoma, S.; Chabrolle, A.; Dimmlich, J.; Engel, E.; Fijn, R.; Fischer, K.; Haelterlein, B.; Haupt, M.; Herrmann, C.; in 't Veld, R.; Kirchhoff, E.; Kristersson, M.; Kuehn, S.; Larsson, K.; Hennig, V.; Larsson, R.; Lawton, N.; Leopold, M.; Lilipaly, S.; Lock, L.; Marty, R.; Matheve, H.; Meissner, W.; Morisson, P.; Newton, S.; Olofsson, P.; Packmor, F.; Pedersen, K. T.; Redfern, C.; Scarton, F.; Schenk, F.; Scher, O.; Serra, L.; Smith, W.; Smith, J.; Sterup, J.; Stienen, E.; Strassner, V.; Valle, R. G.; van Bemmelen, R.; Ve
10.1101/2023.05.12.540367 — ecology — Posted on 2023-05-13
2573 TCRen: predicting TCR recognition of unseen epitopes based on residue-level pairwise statistical potential
Karnaukhov, V. K.; Shcherbinin, D. S.; Chugunov, A. O.; Chudakov, D. M.; Efremov, R. G.; Zvyagin, I. V.; Shugay, M.
10.1101/2022.02.15.480516 — immunology — Posted on 2023-05-13
2577 Diazo-carboxyl click chemistry enables rapid and sensitive quantification of carboxylic acid metabolites
Chen, Z.; Quan, L.; Li, C.; Cheng, K.; Zhao, Q.; Jin, L.; Wang, X.; Liufu, T.; Zhao, X.; Li, X.; Wang, X.; Lyu, J.; Huang, D.; Li, P.; Wang, Z.; Chen, X.-W.; Hu, X.
10.1101/2023.05.11.540288 — systems biology — Posted on 2023-05-13
2578 Mutual antagonism between glucocorticoid and canonical Wnt signaling pathways in B-cell acute lymphoblastic leukemia
Bergeron, B. P.; Barnett, K. R.; Bhattarai, K. R.; Mobley, R. J.; Hansen, B. S.; Brown, A.; Kodali, K.; High, A. A.; Jeha, S.; Pui, C.-H.; Peng, J.; Pruett-Miller, S. M.; Savic, D.
10.1101/2023.01.20.524798 — cancer biology — Posted on 2023-05-13
2579 Exact distribution of the quantal content in synaptic transmission
Rijal, K.; Müller, N. I. C.; Friauf, E.; Singh, A.; Prasad, A.; Das, D.
10.1101/2022.12.28.522121 — biophysics — Posted on 2023-05-13
2586 Persistent hepatitis B virus and HIV coinfections in dually humanized mice engrafted with human liver and immune system
Hogan, G.; Winer, B. Y.; Ahodantin, J.; Sellau, J.; Huang, T. S.; Douam, F.; Funaki, M.; Chiriboga, L.; Su, L.; Ploss, A.
10.1101/2023.05.13.540563 — microbiology — Posted on 2023-05-13
2588 Neuregulin-1 protects against respiratory viral induced mortality
Hussain, S.-R. A.; Rohlfing, M.; Santoro, J.; Resiliac, J.; Chen, P.; Peeples, M. E.; Grayson, M. H.
10.1101/2023.05.10.540232 — immunology — Posted on 2023-05-13
2590 The Bouma law accounts for crowding in fifty observers
Kurzawski, J. W.; Burchell, A.; Thapa, D.; Winawer, J. A.; Majaj, N. J.; Pelli, D. G.
10.1101/2021.04.12.439570 — neuroscience — Posted on 2023-05-13
2591 Attention network drives cortical maturation linked to childhood cognition
Dong, H.; Zhang, X.-H.; Labache, L.; Zhang, S.; Ooi, L. Q. R.; Yeo, B. T. T.; Holmes, A.; Zuo, X.-N.
10.1101/2022.04.12.488101 — neuroscience — Posted on 2023-05-13
2593 Chronic exposure of mice to phthalates enhances TGF beta signaling and promotes uterine fibrosis
Shukla, R.; Mahmuda, A.; Laws, M. J.; Flaws, J. A.; BAGCHI, M. K.; Wagoner Johnson, A. J.; BAGCHI, I. C.
10.1101/2023.05.10.540240 — physiology — Posted on 2023-05-13
2594 OPTIMIZING THERAPEUTIC TARGETS FOR BREAST CANCER USING BOOLEAN NETWORK MODELS
Sgariglia, D.; Goncalves Carneiro, F. R.; Vidal de Carvalho, L. A.; Pedreira, C. E.; Carels, N.; Barbosa da Silva, F. A.
10.1101/2023.05.10.540187 — cancer biology — Posted on 2023-05-13
2595 Antimitotic Activity of Samanea saman Leaf Extract in the In Vitro Development of Tripneustes gratilla Embryo
Lam, J. R.; Casimpan, G.; Villaruel, J. A.; Cuesta, J. Y.; Mabelin, M. K. A.; Rama, J. M.; Cebedo, M. F.; Pepito, M. G.; Climaco, Z.; Simporios, D. J.; Gervacio, J.; Batoy, C.; Grapa, J. B.
10.1101/2023.05.10.540278 — cancer biology — Posted on 2023-05-13
2597 The adhesion capability of S. aureus cells is heterogeneously distributed over the cell envelope
Spengler, C.; Maikranz, E.; Glatz, B. A.; Bischoff, M.; Klatt, M. A.; Santen, L.; Fery, A.; Jacobs, K.
10.1101/2021.01.05.425282 — biophysics — Posted on 2023-05-13
2600 Visualization of the Cdc48 AAA+ ATPase protein unfolding pathway
Cooney, I.; Schubert, H. L.; Cedeno, K.; Lin, H.-J. L.; Price, J. C.; Hill, C. P.; Shen, P. S.
10.1101/2023.05.13.540638 — biochemistry — Posted on 2023-05-13
2601 Centromere Innovations Within a Mouse Species
Gambogi, C. W.; Pandey, N.; Dawicki-McKenna, J. M.; Arora, U. P.; Liskovykh, M. A.; Ma, J.; Lamelza, P.; Larionov, V.; Lampson, M. A.; Logsdon, G. A.; Dumont, B. L.; Black, B. E.
10.1101/2023.05.11.540353 — genomics — Posted on 2023-05-13
2602 Cytoplasmic polyadenylation is an ancestral hallmark of early development in animals
Rouhana, L.; Edgar, A.; Hugosson, F.; Dountcheva, V.; Martindale, M. Q.; Ryan, J. F.
10.1101/2023.05.10.540224 — evolutionary biology — Posted on 2023-05-13
2603 Microbiome ssRNA as an environmental cue to activate TLR13-dependent tissue-protective programs in CD5Lhi hepatic macrophages
Sato, R.; Liu, K.; Shibata, T.; Hoshino, K.; Yamaguchi, K.; Miyazaki, T.; Hiranuma, R.; Fukui, R.; Motoi, Y.; Fukuda-Ohta, Y.; Zhang, Y.; Reuter, T.; Ishida, Y.; Kondo, T.; Chiba, T.; Asahara, H.; Taoka, M.; Yamauchi, Y.; Isobe, T.; Kaisho, T.; Furukawa, Y.; Latz, E.; MIYAKE, K.
10.1101/2023.05.11.540294 — immunology — Posted on 2023-05-13
2607 The renal capsule: a vibrant and adaptive cell environment of the kidney in homeostasis, disease and aging
Korin, B.; Avraham, S.; Moncada, R.; Ho, T.; Tleugabulova, M. C.; Menon, H.; Darmanis, S.; Liang, Y.; Modrusan, Z.; Chalouni, C.; Victoria, C.; Rangell, L.; Havnar, C.; Ewart, W.; Jones, C.; Jiang, J.; Dunlap, D.; Dohse, M.; McKay, A.; Webster, J. D.; Durinck, S.; Shaw, A. S.
10.1101/2023.05.11.540033 — immunology — Posted on 2023-05-13
2608 A network-based model of Aspergillus fumigatus elucidates regulators of development and defensive natural products of an opportunistic pathogen
Carrera Carriel, C. X.; Pyne, S.; Halberg-Spencer, S. A.; Park, S. C.; Seo, H.-w.; Schmidt, A.; Calise, D. G.; Ane, J.-M.; Keller, N. P.; Roy, S.
10.1101/2023.05.11.538573 — systems biology — Posted on 2023-05-13
2609 Neuro-Regenerative Behavior of Adipose-Derived Stem Cells in Aligned Collagen I Hydrogels
Lewis, M.; David, G.; Jacobs, D.; Woessner, A. E.; Kuczwara, P.; Kim, J.-W.; Quinn, K. P.; Song, Y.
10.1101/2023.05.12.539636 — bioengineering — Posted on 2023-05-13
2610 Custom-engineered hydrogels for delivery of human iPSC-derived neurons into the injured cervical spinal cord
Doulames, V. M.; Marquardt, L. M.; Hefferon, M. E.; Baugh, N. J.; Suhar, R. A.; Wang, A. T.; Dubbin, K.; Weimann, J. M.; Palmer, T. D.; Plant, G. W.; Heilshorn, S. C.
10.1101/2023.05.10.540225 — bioengineering — Posted on 2023-05-13
2611 Conserving a threatened North American walnut: a chromosome-scale reference genome for butternut (Juglans cinerea)
Guzman-Torres, C. R.; Trybulec, E.; LeVasseur, H.; Akella, H.; Amee, M.; Strickland, E.; Pauloski, N.; Williams, M.; Romero-Severson, J.; Hoban, S.; Woeste, K.; Pike, C.; Fetter, K. C.; Webster, C. N.; Neitzey, M. L.; O'Neill, R.; Wegrzyn, J. L.
10.1101/2023.05.12.539246 — genomics — Posted on 2023-05-13
2612 It All Rolls Downstream: Upstream Control of Physical Activity Regulation
Breidenbach, B. M.; Liu, L.; La, T.; Castro-Padovani, T. N.; Keller, N.; Pescatello, L. S.; Robinson, M. M.; Kelly, S. A.; Gerrish, K.; Lightfoot, J. T.
10.1101/2023.05.10.540028 — genetics — Posted on 2023-05-13
2615 Ex-Lactobacillus Strains with Intrinsic Propensity to Stabilize Pickering Oil-in-Water Emulsions
Muhammed, M. K.; Jiang, X.; Shekarforoush, E.; Whitehead, K.; Vogensen, F. K.; Risbo, J.; Arneborg, N.
10.1101/2023.05.13.540633 — microbiology — Posted on 2023-05-13
2619 Regulation of shelterin proteins TERF2IP and TRF2 by H3K4me3-p65 axis drives hyperglycemia dependent endothelial senescence
Thakar, S.; Bhattacharya, R.; Katakia, Y. T.; Chakraborty, S.; Ramakrishnan, S.; Thakkar, N. P.; Dey, S.; Chowdhury, S.; Majumder, S.
10.1101/2023.05.12.540614 — biochemistry — Posted on 2023-05-13
2621 Molecular Basis for Maternal Inheritance of Human Mitochondrial DNA
Lee, W.; Zamudio-Ochoa, A.; Buchel, G.; Podlesniy, P.; Marti Gutierrez, N.; Puigros, M.; Calderon, A.; Koski, A.; Tang, H.-Y.; Li, L.; Trullas, R.; Mitalipov, S.; Temiakov, D.
10.1101/2023.05.12.540615 — molecular biology — Posted on 2023-05-13
2625 Modulation of infraslow oscillation in the dentate gyrus during Non-REM sleep
Turi, G. F.; Chen, X.; Teng, S.; Lim, E. C.; Dias, C.; Hu, R.; Zhen, F.; Peng, Y.
10.1101/2023.05.12.540575 — neuroscience — Posted on 2023-05-13
2626 Hierarchical gradient of timescales in the mammalian forebrain
Song, M.; Shin, E. J.; Seo, H.; Soltani, A.; Steinmetz, N. A.; Lee, D.; Jung, M. W.; Paik, S.-B.
10.1101/2023.05.12.540610 — neuroscience — Posted on 2023-05-13
2628 Sex differences in binge alcohol drinking and the behavioral consequences of protracted withdrawal in C57BL/6J mice
Rivera-Irizarry, J. K.; Zallar, L. J.; Levine, O. B.; Skelly, M. J.; Boyce, J. E.; Barney, T.; Kopyto, R.; Pleil, K. E.
10.1101/2023.05.12.540565 — animal behavior and cognition — Posted on 2023-05-13
2631 Intermediate basal cell population in prostate homeostasis and cancer initiation
Guo, W.; Zhang, X.; Li, L.; Shao, P.; Zhang, H.; Liu, K.; Liang, C.; Wang, S.; Peng, Y.; Ju, Y.; Yu, C.; Chen, L.; Zhou, B.; Gao, D.
10.1101/2023.05.12.540502 — developmental biology — Posted on 2023-05-13
2632 LRP10 as a novel α-synuclein regulator in Lewy body diseases
Carreras Mascaro, A.; Grochowska, M. M.; Boumeester, V.; Dits, N. F. J.; Bilgic, E. N.; Breedveld, G. J.; Vergouw, L.; de Jong, F. J.; van Royen, M. E.; Bonifati, V.; Mandemakers, W.
10.1101/2023.05.12.540510 — neuroscience — Posted on 2023-05-13
2633 Integrative single-nucleus multi-omics analysis prioritizes candidate cis and trans regulatory networks and their target genes in Alzheimers disease brains
Gamache, J. E.; Gingerich, D. C.; Shwab, E. K.; Barrera, J. A.; Garrett, M. E.; Hume, C.; Crawford, G. E.; Ashley-Koch, A. E.; Chiba-Falek, O.
10.1101/2023.05.12.540037 — neuroscience — Posted on 2023-05-13
2635 Decentralized Mixed Effects Modeling in COINSTAC
Basodi, S.; Raja, R.; Gazula, H.; Romero, J. T.; Panta, S.; Maullin-Sapey, T. J.; Nichols, T. E.; Calhoun, V. D.
10.1101/2023.05.12.540598 — neuroscience — Posted on 2023-05-13
2636 Hippocampome.org v2.0: a knowledge base enabling data-driven spiking neural network simulations of rodent hippocampal circuits
Wheeler, D. W.; Kopsick, J. D.; Sutton, N.; Tecuatl, C.; Komendantov, A. O.; Nadella, K.; Ascoli, G. A.
10.1101/2023.05.12.540597 — neuroscience — Posted on 2023-05-13
2637 Deep learning-driven characterization of single cell tuning in primate visual area V4 unveils topological organization
Willeke, K. F.; Restivo, K.; Franke, K.; Nix, A. F.; Cadena, S. A.; Shinn, T.; Nealley, C.; Rodriguez, G.; Patel, S.; Ecker, A. S.; Sinz, F. H.; Tolias, A. S.
10.1101/2023.05.12.540591 — neuroscience — Posted on 2023-05-13
2641 Inactivating Negative Regulators of Cortical Branched Actin Enhances Persistence of Single Cell Migration
Fokin, A. I.; Boutillon, A.; James, J.; Courtois, L.; Vacher, S.; Simanov, G.; Wang, Y.; Polesskaya, A.; Bieche, I.; David, N. B.; Gautreau, A. M.
10.1101/2023.05.13.540631 — cell biology — Posted on 2023-05-13
2642 Functional Characterization of Calmodulin-like Proteins, CML13 and CML14, as Novel Light Chains of Arabidopsis Class VIII Myosins
Symonds, K.; Teresinski, H. J.; Hau, B.; Sadot, E.; Dwivedi, V.; Belausov, E.; Bar-Sinai, S.; Tominaga, M.; Haraguchi, T.; Ito, K.; Snedden, W.
10.1101/2023.05.12.540561 — plant biology — Posted on 2023-05-13
2643 Transcription-directed membrane association organizes the chloroplast nucleoid structure
Palomar, V. M.; Fujii, S.; Rothi, M. H.; Jaksich, S.; Coke, A. N.; Wang, J.; Wierzbicki, A. T.
10.1101/2023.05.12.540520 — plant biology — Posted on 2023-05-13
2649 A Robust Deep Learning Approach for Joint Nuclei Detection and Cell Classification in Pan-Cancer Histology Images
Walia, V.; Kotte, S.; Sivadasan, N.; Sharma, H.; Joseph, T.; Varma, B.; Mukherjee, G.; V.G, S.
10.1101/2023.05.10.540156 — pathology — Posted on 2023-05-12
2652 Advancing multi-day ex vivo kidney perfusion using spatially resolved metabolomics
de Haan, M. J. A.; Witjas, F. M. R.; de Graaf, A. M. A.; Jacobs, M. E.; Sanchez-Lopez, E.; Kostidis, S.; Giera, M. A.; Maanaoui, M.; Hubert, T.; Kerr-Conte, J.; Pattou, F.; de Vries, D. K.; Kers, J.; Alwayn, I. P. J.; van Kooten, C.; Heijs, B. P. A. M.; Wang, G.; Engelse, M. A.; Rabelink, T. J.
10.1101/2023.05.10.540143 — bioengineering — Posted on 2023-05-12
2653 Development of genomic markers associated to production traits in lumpfish (Cyclopterus lumpus)
Gutierrez, A. P.; Counter Selly, S.-L.; Taggart, J. B.; Kokkinias, P.; Cavrois-Rogacki, T.; Jimenez Fernandez, E.; Migaud, H.; Lein, I.; Davie, A.; Bekaert, M.
10.1101/2023.05.10.540148 — genomics — Posted on 2023-05-12
2658 The gut microbiome mediates adaptation to scarce food in Coleoptera
Moldovan, O.; Carrell, A.; Bulzu, P.; Levei, E.; Bucur, R.; Sitar, C.; Faur, L.; Mirea, I.; Senila, M.; Cadar, O.; Podar, M. A.
10.1101/2023.05.12.540564 — ecology — Posted on 2023-05-12
2660 Spatial and functional arrangement of Ebola virus polymerase inside phase-separated viral factories
Fang, J.; Castillon, G.; Phan, S.; McArdle, S.; Hariharan, C.; Adams, A.; Ellisman, M. H.; Deniz, A. A.; Saphire, E. O.
10.1101/2022.12.27.522024 — microbiology — Posted on 2023-05-12
2662 Analysis of in-patient evolution of Escherichia coli reveals potential links to relapse of bone and joint infections
Thiriet Rupert, S.; Josse, J.; Perez Pascual, D.; Tasse, J.; Andre, C.; Abad, L.; Lebeaux, D.; Ghigo, J.-M.; Laurent, F.; Beloin, C.
10.1101/2023.05.10.540183 — microbiology — Posted on 2023-05-12
2663 The chicken chorioallantoic membrane model for isolation of CRISPR/cas9-based HSV-1 mutant expressing tumor suppressor p53
Kelishadi, M.; Shahsavarani, H.; Tabarraei, A.; Shokrgozar, M. A.; Teimoori-Toolabi, L.; Azadmanesh, K.
10.1101/2023.05.12.540548 — microbiology — Posted on 2023-05-12
2664 Mutational scanning pinpoints distinct binding sites of key ATGL regulators in lipolysis
Kohlmayr, J. M.; Grabner, G. F.; Nusser, A.; Hoell, A.; Halwachs, B.; Jany-Luig, E.; Engelke, H.; Zimmermann, R.; Stelzl, U.
10.1101/2023.05.10.540188 — systems biology — Posted on 2023-05-12
2666 Leveraging genetic correlation structure to target discrete signaling mechanisms across metabolic tissues
Zhou, M.; Van, C.; Molendijk, J.; Chang, I. Y.-Y.; Johnson, C.; Velez, L. M.; Yeo, R.; Bae, H.; Le, J.; Larson, N.; Pulido, R.; Nascimento-Filho, C.; Hevener, A. L.; Sparks, L.; Justice, J.; Kershaw, E.; Marazzi, I.; Pannunzio, N.; Nicholas, D.; Parker, B. L.; Jang, C.; Masri, S.; Seldin, M. M.
10.1101/2023.05.10.540142 — physiology — Posted on 2023-05-12
2667 KLIPP - a precision CRISPR approach to target structural variant junctions in cancer
Yang, H.; Hulbatte, R. S.; Kellher, A.; Gratsch, N.; Wang, Y.; Palmbos, P.; Ljungman, M.
10.1101/2023.05.10.540176 — cancer biology — Posted on 2023-05-12
2669 Crosstalk between the glucocorticoid and mineralocorticoid receptor boosts glucocorticoid-induced killing of multiple myeloma cells
Clarisse, D.; Prekovic, S.; Vlummens, P.; Staessens, E.; Van Wesemael, K.; Thommis, J.; Fijalkowska, D.; Acke, G.; Zwart, W.; Beck, I. M.; Offner, F.; De Bosscher, K.
10.1101/2023.05.10.540157 — cancer biology — Posted on 2023-05-12
2673 Conformational changes in the essential E. coli septal cell wall synthesis complex suggest an activation mechanism
Britton, B. M.; Yovanno, R. A.; Costa, S. F.; McCausland, J.; Lau, A. Y.; Xiao, J.; Hensel, Z.
10.1101/2022.11.27.518129 — biophysics — Posted on 2023-05-12
2675 circRNA-sponging: a pipeline for extensive analysis of circRNA expression and their role in miRNA sponging
Hoffmann, M.; Schwartz, L.; Ciora, O.-A.; Trummer, N.; Willruth, L.-L.; Jankowski, J.; Lee, H. K.; Baumbach, J.; Furth, P. A.; Hennighausen, L.; List, M.
10.1101/2023.01.19.524495 — bioinformatics — Posted on 2023-05-12
2676 Deconvolution of ex-vivo drug screening data and bulk tissue expression predicts the abundance and viability of cancer cell subpopulations
Alexandre, C.; Forey, R.; Bejar Haro, B.; Martins, F.; Carlevaro-Fita, J.; Sheppard, S.; Offner, S. E.; La Manno, G.; Obozinski, G.; Trono, D.
10.1101/2023.05.10.540140 — bioinformatics — Posted on 2023-05-12
2677 Predicting T Cell Receptor Functionality against Mutant Epitopes
Dorigatti, E.; Drost, F.; Straub, A.; Hilgendorf, P.; Wagner, K. I.; Bischl, B.; Busch, D.; Schober, K.; Schubert, B.
10.1101/2023.05.10.540189 — bioinformatics — Posted on 2023-05-12
2678 Designing molecular RNA switches with Restricted Boltzmann machines
Fernandez-de-Cossio-Diaz, J.; Hardouin, P.; Lyonnet du Moutier, F.-X.; Di Gioacchino, A.; Marchand, B.; Ponty, Y.; Sargueil, B.; Monasson, R.; Cocco, S.
10.1101/2023.05.10.540155 — bioinformatics — Posted on 2023-05-12
2683 A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X
Jowhar, Z.; Xu, A.; Venkataramanan, S.; Hoye, M. L.; Silver, D. L.; Floor, S. N.; Calviello, L.
10.1101/2023.05.11.540322 — genomics — Posted on 2023-05-12
2684 The Host Adapted Fungal Pathogens of Pneumocystis Genus Utilize Genic Regional Centromeres
Cisse, O. H.; Curran, S.; Folco, H. D.; Liu, Y.; Bishop, L.; Wang, H.; Fischer, E. R.; Davis, A. S.; Babb-Biernacki, S.; Doyle, V. P.; Richards, J. K.; Hassan, S. A.; Dekker, J. P.; Khil, P. P.; Brenchley, J. M.; Grewal, S.; Cushion, M.; Ma, L.; Kovacs, J. A.
10.1101/2023.05.12.540427 — genomics — Posted on 2023-05-12
2686 Striking allelic diversity despite structural homogeneity of ace-1 duplications in Anopheles mosquitoes
CLARET, J.-L.; Di-Liegro, M.; Namias, A.; Assogba, B. S.; Makoundou, P.; Koffi, A.; Pennetier, C.; Weill, M.; Milesi, P.; Labbe, P.
10.1101/2023.05.10.539957 — evolutionary biology — Posted on 2023-05-12
2688 Sonic Hedgehog Activates Prostaglandin Signaling to Stabilize Primary Cilium Length
Ansari, S. S.; Dillard, M. E.; Zhang, Y.; Austria, M. A.; Boatwright, N.; Shelton, E. L.; Johnson, A.; Young, B. M.; Rankovic, Z.; Schuetz, J. D.; Robinson, C. G.; Ogden, S. K.
10.1101/2022.05.06.490951 — cell biology — Posted on 2023-05-12
2689 Clinorotation inhibits myotube formation by fluid motion, not by simulated microgravity
Mansour, J.; Berwanger, C.; Jung, M.; Eichinger, L.; Fabry, B.; Clemen, C. S.
10.1101/2023.02.10.527979 — cell biology — Posted on 2023-05-12
2690 ADSC-EVs modulate primary human macrophages to an anti-inflammatory phenotype in vitro
Symonds, E. K. C.; Black, B.; Brown, A.; Meredith, I.; Currie, M.; Hally, K. E.; Danielson, K. M.
10.1101/2023.05.11.540448 — molecular biology — Posted on 2023-05-12
2691 High number of HPAI H5 Virus Infections and Antibodies in Wild Carnivores in the Netherlands, 2020-2022
Chestakova, I.; van der Linden, A.; Bellido Martin, B.; Caliendo, V.; Vuong, O.; Thewessen, S.; Hartung, T.; Bestebroer, T.; Dekker, J.; Jonge Poerink, B.; Grone, A.; Koopmans, M.; Fouchier, R.; van den Brand, J.; Sikkema, R. S.
10.1101/2023.05.12.540493 — microbiology — Posted on 2023-05-12
2694 A new fluorescence-based approach for direct visualization of coat formation during sporulation in Bacillus cereus
Lablaine, A.; Chamot, S.; Serrano, M.; Billaudeau, C.; Bornard, I.; Carballido-Lopez, R.; Carlin, F.; Henriques, A. O.; Broussolle, V.
10.1101/2023.05.12.540479 — microbiology — Posted on 2023-05-12
2696 SMRT-AgRenSeq-d in potato (Solanum tuberosum) identifies candidates for the nematode resistance Gpa5
Wang, Y.; Brown, L. H.; Adams, T. M.; Cheung, Y. W.; Li, J.; Young, V.; Todd, D. T.; Armstrong, M. R.; Neugebauer, K.; Kaur, A.; Harrower, B.; Oome, S.; Wang, X.; Bayer, M.; Hein, I.
10.1101/2022.12.08.519582 — plant biology — Posted on 2023-05-12
2697 Mechanism-guided quantification of LINE-1 reveals p53 regulation of both retrotransposition and transcription
Solovyov, A.; Behr, J. M.; Hoyos, D.; Banks, E. M.; Drong, A. W.; Zhong, J. Z.; Garcia-Rivera, E.; McKerrow, W.; Chu, C.; Zaller, D. M.; Fromer, M.; Greenbaum, B. D.
10.1101/2023.05.11.539471 — cancer biology — Posted on 2023-05-12
2699 PhosphoLingo: protein language models for phosphorylation site prediction
Zuallaert, J.; Ramasamy, P.; Bouwmeester, R.; Callewaert, N.; Degroeve, S.
10.1101/2022.11.28.518163 — bioinformatics — Posted on 2023-05-12
2701 Anionic phospholipids stimulate the proton pumping activity of the plant plasma membrane P-type H+-ATPase
Paweletz, L. C.; Holtbrügge, S. L.; Löb, M.; De Vecchis, D.; Schäfer, L. V.; Günther Pomorski, T.; Justesen, B. H.
10.1101/2023.05.12.540525 — biochemistry — Posted on 2023-05-12
2702 Thioflavin T In-gel Stain to Study Protein Misfolding in Frozen Tissue Specimens
Oldam, J.; Tchernyshyov, I.; Van Eyk, J.; Troncoso, J.; Glabe, C. G.; Agnetti, G.
10.1101/2023.05.12.540528 — biochemistry — Posted on 2023-05-12
2704 Mix-and-extrude: high-viscosity sample injection towards time-resolved protein crystallography
Vakili, M.; Han, H.; Schmidt, C.; Wrona, A.; Kloos, M.; de Diego, I.; Dorner, K.; Geng, T.; Kim, C.; Koua, F.; Melo, D.; Rappas, M.; Round, A.; Round, E.; Sikorski, M.; Valerio, J.; Zhou, T.; Lorenzen, K.; Schulz, J.
10.1101/2022.11.23.517685 — biochemistry — Posted on 2023-05-12
2705 FUS binding to RNA prevents R-loops
Thompson, V. F.; Wieland, D. R.; Mendoza-Leon, V.; Janis, H. I.; Lay, M. A.; Harrell, L. M.; Schwartz, J. C.
10.1101/2022.08.11.503633 — biochemistry — Posted on 2023-05-12
2707 Transposon elements shape population divergence of rice blast fungus Magnaporthe oryzae
Zheng, H.; Lin, L.; Sun, T.; Guo, J.; Lin, L.; Chen, M.; Wang, Z.; Bao, J.-D.; Norvienyeku, J.; Han, Y.; Lu, G.; Rensing, C.; Zhong, Z.; Wang, Z.
10.1101/2023.05.12.540556 — genomics — Posted on 2023-05-12
2708 Calling pangenes from plant genome alignments confirms presence-absence variation
Contreras-Moreira, B.; Saraf, S.; Naamati, G.; Casas, A. M.; Amberkar, S. S.; Flicek, P.; Jones, A. R.; Dyer, S.
10.1101/2023.01.03.520531 — genomics — Posted on 2023-05-12
2710 Quantifying the relationship between cell proliferation and morphology during development of the face
Green, R. M.; Lo Vercio, L.; Dauter, A.; Barretto, E. C.; Devine, J.; Vidal Garcia, M.; Marchini, M.; Robertson, S.; Zhao, X.; Mahika, A.; Shakir, M. B.; Guo, S.; Boughner, J. C.; Dean, W.; Lander, A. D.; Marcucio, R. S.; Forkert, N. D.; Hallgrimsson, B.
10.1101/2023.05.12.540515 — developmental biology — Posted on 2023-05-12
2711 Transient expression of Helicobacter pylori cagA oncoprotein in brinjal
Mehran, M. J.; Barzigar, R.; Basaralu Yadurappa, S. K.; Haraprasad, N.; Fakrudin, B.; Paul, S.; Ramasamy, R. K.; Malla, S.
10.1101/2023.05.12.540570 — molecular biology — Posted on 2023-05-12
2712 Can BioSAXS Detect Ultrastructural Changes Of Antifungal Compounds In Candida Albicans? - An Exploratory Study
Hilpert, K.; Rumancev, C.; Gani, J.; Collis, D. W. P.; Lopez-Perez, P. M.; Garamus, V. M.; Mikut, R.; Rosenhahn, A.
10.1101/2023.05.12.540542 — microbiology — Posted on 2023-05-12
2717 Antimicrobial Resistance Profiles of Bacterial Contaminants from a Tertiary Hospital in Kenya: An Urgent Call for Action Against the Global Threat of Antimicrobial Resistance.
Kolek, C.; Kavulavu, B. M.; Okalebo, F.; Singa, B.; Masheti, M.; Omuom, I.; Odhoch, O.; Oduol, C.; Tigoi, C.; Musyimi, R.; Tickell, K. D.
10.1101/2023.05.11.540441 — microbiology — Posted on 2023-05-12
2719 Transcription coactivator OCA-B/Pou2af1 is sufficient to promote T cell-intrinsic CD4 memory and prospectively identifies memory precursors
Sun, W.; Kim, H.; Hughes, E. P.; Perovanovic, J.; Charley, K. R.; Du, J.; Ibarra, A.; Hale, J. S.; Williams, M. A.; Tantin, D.
10.1101/2022.09.21.508912 — immunology — Posted on 2023-05-12
2720 PKR-mediated Stress Response Enhances Dengue and Zika Virus Replication
Ricciardi-Jorge, T.; Lummertz da Rocha, E.; Gonzalez-Kozlova, E.; Rodrigues-Luiz, G. F.; Ferguson, B. J.; Sweeney, T.; Irigoyen, N.; Mansur, D. S.
10.1101/2021.04.08.439069 — immunology — Posted on 2023-05-12
2724 A ubiquitous spectrolaminar motif of local field potential power across the primate cortex
Mendoza-Halliday, D.; Major, A. J.; Lee, N.; Lichtenfeld, M.; Carlson, B.; Mitchell, B.; Meng, P. D.; Xiong, Y.; Westerberg, J. A.; Maier, A.; Desimone, R.; Miller, E. K.; Bastos, A. M.
10.1101/2022.09.30.510398 — neuroscience — Posted on 2023-05-12
2729 Transcriptome Analysis Reveals Organ-Specific Effects of 2-Deoxyglucose Treatment in Healthy Mice
Wells, A. E.; Wilson, J. J.; Sears, J. D.; Wei, J.; Heuer, S.; Pandey, R.; Costa, M. W.; Kaczorowski, C. C.; Roopenian, D. C.; Chang, C.-H.; Carter, G. W.
10.1101/2023.04.24.537717 — systems biology — Posted on 2023-05-12
2732 Mapping cells through time and space with moscot
Klein, D.; Palla, G.; Lange, M.; Klein, M.; Piran, Z.; Gander, M.; Meng-Papaxanthos, L.; Sterr, M.; Bastidas-Ponce, A.; Tarquis-Medina, M.; Lickert, H.; Bakhti, M.; Nitzan, M.; Cuturi, M.; Theis, F. J.
10.1101/2023.05.11.540374 — bioinformatics — Posted on 2023-05-12
2733 nucMACC: An optimized MNase-seq pipeline measures genome-wide nucleosome accessibility and stability
Wernig-Zorc, S.; Kugler, F.; Schmutterer, L.; Raess, P.; Hausmann, C.; Holzinger, S.; Laengst, G.; Schwartz, U.
10.1101/2022.12.29.521985 — bioinformatics — Posted on 2023-05-12
2737 Spatial scenario of tropical deforestation and carbon emissions for the 21st century
Vieilledent, G.; Vancutsem, C.; Bourgoin, C.; Ploton, P.; Achard, F.; Verley, P.
10.1101/2022.03.22.485306 — ecology — Posted on 2023-05-12
2740 An integrative multi-omics approach to draft gene regulatory networks at a cell type resolution
Voronov, D.; Paganos, P.; Magri, M. S.; Cuomo, C.; Maeso, I.; Gomez-Skarmeta, J. L.; Arnone, M. I.
10.1101/2023.05.12.540495 — developmental biology — Posted on 2023-05-12
2741 The action of physiological and synthetic steroids on the calcium channel CatSper in human sperm
Wehrli, L.; Galdadas, I.; Voirol, L.; Smiesko, M.; Cambet, Y.; Jaquet, V.; Guerrier, S.; Gervasio, F.; Nef, S.; Rahban, R.
10.1101/2023.05.10.540165 — cell biology — Posted on 2023-05-12
2742 Rapid cloning-free mutagenesis of new SARS-CoV-2 variants using a novel reverse genetics platform
Kipfer, E. T.; Hauser, D.; Lett, M. J.; Otte, F.; Urda, L.; Zhang, Y.; Lang, C. M. R.; Chami, M.; Mittelholzer, C.; Klimkait, T.
10.1101/2023.05.11.540343 — molecular biology — Posted on 2023-05-12
2745 Antibodies Raised Against an Aβ Oligomer Mimic Recognize Pathological Features in Alzheimer's Disease and Associated Amyloid-Disease Brain Tissue
Kreutzer, A. G.; Parrocha, C. M. T.; Haerianardakani, S.; Guaglianone, G.; Nguyen, J. T.; Diab, M. N.; Yong, W.; Perez-Rosendahl, M.; Head, E.; Nowick, J. S.
10.1101/2023.05.11.540404 — neuroscience — Posted on 2023-05-12
2747 Metabolic response of microglia to amyloid deposition during Alzheimer's disease progression in a mouse model
Marino, K. M.; Squirrell, J. M.; Chacko, J. V. M.; Watters, J. J.; Eliceiri, K. W.; Ulland, T.
10.1101/2023.05.12.540407 — neuroscience — Posted on 2023-05-12
2748 Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer's disease.
Chartampila, E.; Elayouby, K. S.; Leary, P.; LaFrancois, J. J.; Alcantara-Gonzalez, D.; Jain, S.; Gerencer, K.; Botterill, J. J.; Ginsberg, S. D.; Scharfman, H.
10.1101/2023.05.12.540428 — neuroscience — Posted on 2023-05-12
2750 Fluctuation of lysosomal protein degradation in neural stem cells of postnatal mouse brain
Kobayashi, T.; Zhang, H.; Ishii, K.; Shibata, T.; Ishii, S.; Hirao, M.; Lu, Z.; Takamura, R.; Kitano, S.; Miyachi, H.; Kageyama, R.; Itakura, E.
10.1101/2023.05.12.540513 — neuroscience — Posted on 2023-05-12
2751 Circadian rhythms in the gut microbiota shape sex differences in host gene expression and metabolism
Munyoki, S. K.; Goff, J. P.; Kolobaric, A.; Long, A.; Mullett, S. J.; Burns, J. K.; Jenkins, A. K.; DePoy, L. M.; Wendell, S. G.; McClung, C. A.; Morrison, K. E.; Jasarevic, E.
10.1101/2022.09.15.508006 — systems biology — Posted on 2023-05-12
2754 Epithelial-Mesenchymal Transition: An Organizing Principle of Mammalian Regeneration
Bedelbaeva, K.; Cameron, B.; Latella, J.; Aslanukov, A.; Gourevitch, D.; Davuluri, R. V.; Heber-Katz, E.
10.1101/2023.05.11.539303 — developmental biology — Posted on 2023-05-12
2755 Near-field potentials index local neural computations more accurately than population spiking
Tovar, D. A.; Westerberg, J. A.; Cox, M. A.; Dougherty, K.; Wallace, M.; Bastos, A. M.; Maier, A.
10.1101/2023.05.11.540026 — neuroscience — Posted on 2023-05-12
2758 Effect of ketamine on early synaptic mistuning and emotional behavior deficits in AppNL-F mouse model of Alzheimer's disease.
Portal, B.; Sodergren, M.; Pares i Borrell, T.; Metzendorf, N.; Hultqvist, G.; Nilsson, P.; Lindskog, M.
10.1101/2023.05.12.540486 — neuroscience — Posted on 2023-05-12
2759 Network and State Specificity in Connectivity-Based Predictions of Individual Behavior
Kraljevic, N.; Langner, R.; Küppers, V.; Raimondo, F.; Patil, K. R.; Eickhoff, S. B.; Müller, V. I.
10.1101/2023.05.11.540387 — neuroscience — Posted on 2023-05-12
2761 Elevated nuclear TDP-43 induces constitutive exon skipping
Carmen-Orozco, R. P.; Tsao, W.; Ye, Y.; Sinha, I. R.; Chang, K.; Trinh, V.; Chung, W.; Bowden, K. D.; Troncoso, J. C.; Blackshaw, S.; Hayes, L. R.; Sun, S.; Wong, P. C.; Ling, J. P.
10.1101/2023.05.11.540291 — neuroscience — Posted on 2023-05-12
2762 Activity of brain stem glucagon neurons are modulated by energy state and encode sex and frequency-dependent negative valence and anxiety.
Lopez, C. B.; Duran, M.; Virkus, S. A.; Yadav, E.; McMichen, K.; Singh, J.; Ramsey, V.; Stocking, S.; Habegger, K. M.; Hardaway, J. A.
10.1101/2023.05.11.540425 — neuroscience — Posted on 2023-05-12
2763 Reliability of resting-state EEG modulation by continuous and intermittent theta burst stimulation of the primary motor cortex: A sham-controlled study
Rodionov, A.; Ozdemir, R. A.; Benwell, C. S. Y.; Fried, P. J.; Boucher, P.; Momi, D.; Ross, J. M.; Santarnecchi, E.; Pascual-Leone, A.; Shafi, M. M.
10.1101/2023.05.12.540024 — neuroscience — Posted on 2023-05-12
2767 Multi-site identification and generalization of clusters of walking impairment in individuals with chronic stroke
Sanchez, N.; Schweighofer, N.; Mulroy, S.; Roemmich, R. T.; Kesar, T. M.; Torres-Oviedo, G.; Fisher, B. E.; Finley, J.; Winstein, C. J.
10.1101/2023.05.11.540385 — neuroscience — Posted on 2023-05-12
2771 Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/Stat3 attenuation
Balcioglu, O.; Gates, B. L.; Freeman, D. W.; Hagos, B. M.; Mehrabad, E. M.; Ayala-Talavera, D.; Spike, B. T.
10.1101/2023.05.10.540211 — cancer biology — Posted on 2023-05-12
2775 Thrombocytopenia Independently Leads to Monocyte Immune Dysfunction
Li, C.; Ture, S. K.; Nieves, B.; Blick-Nitko, S. K.; Maurya, P.; Livada, A. C.; Stahl, T.; Kim, M.; Pietropaoli, A.; Morrell, C. N.
10.1101/2023.05.10.540214 — immunology — Posted on 2023-05-12
2778 Respiratory Complex I Regulates Dendritic Cell Maturation in Explant Model of Human Tumor Immune Microenvironment
Turpin, R.; Liu, R.; Munne, P.; Peura, A.; Rannikko, J. H.; Philips, G.; Boeckx, B.; Salmelin, N.; Hurskainen, E.; Suleymanova, I.; Vuorinen, E. M.; Lehtinen, L.; Mutka, M.; Kovanen, P. E.; Niinikoski, L.; Meretoja, T.; Mattson, J.; Mustjoki, S.; Saavalainen, P.; Goga, A.; Lambrechts, D.; Pouwels, J.; Hollmen, M.; Klefstrom, J.
10.1101/2023.05.10.539944 — cancer biology — Posted on 2023-05-12
2779 A GALLIUM-68-LABELED PEPTIDE RADIOTRACER FOR CD38-TARGETED IMAGING IN MULTIPLE MYELOMA WITH PET
Sharma, A. K.; Gupta, K.; Mishra, A.; Lofland, G.; Marsh, I.; Kumar, D.; Ghiaur, G.; Imus, P.; Hobbs, R. F.; Gocke, C.; Nimmagadda, S.
10.1101/2023.05.09.540036 — cancer biology — Posted on 2023-05-12
2780 KLIPP - a precision CRISPR approach to target structural variant junctions in cancer
Yang, H.; Hulbatte, R. S.; Kellher, A.; Gratsch, N.; Wang, Y.; Palmbos, P.; Ljungman, M.
10.1101/2023.05.10.540176 — cancer biology — Posted on 2023-05-12
2782 Prostate-derived circulating microRNAs add prognostic value to prostate cancer risk calculators
Nonn, L.; Zenner, M. L.; Kirkpatrick, B.; Leonardo, T. R.; Schlicht, M. J.; Saldana, A. C.; Loitz, C.; Valyi-Nagy, K.; Maienschein-Cline, M.; Gann, P. H.; Abern, M.
10.1101/2023.05.10.540236 — cancer biology — Posted on 2023-05-12
2786 In silico mechanics and TGF-β expression of stem cells intramyocardially transplanted with a biomaterial injectate for treatment of myocardial infarction
Motchon, Y. D.; Sack, K. L.; Sirry, M. S.; Nchejane, N. J.; Abdalrahman, T.; Nagawa, J.; Kruger, M.; Pauwels, E.; Van Loo, D.; De Muynck, A.; Van Hoorebeke, L.; Davies, N. H.; Franz, T.
10.1101/2023.05.10.540185 — bioengineering — Posted on 2023-05-12
2789 17 β-estradiol impedes aortic root dilation and rupture in male Marfan mice
Saddic, L.; Escopete, S.; Zilberberg, L.; Kalsow, S.; Gupta, D.; Parker, S.
10.1101/2023.05.09.540071 — genetics — Posted on 2023-05-12
2791 Exact calculation of the expected SFS in structured populations
Arredondo, A.; Corujo, J.; Nous, C.; Boitard, S.; Chikhi, L.; Mazet, O.
10.1101/2023.05.10.540112 — genetics — Posted on 2023-05-12
2794 Morphological limitations imposed on lizards facing urbanization
Row, K. W.; Villasana-Espinosa, O.; Perez, J.; Urbina, G.; Frishkoff, L. O.
10.1101/2023.05.09.540039 — ecology — Posted on 2023-05-12
2795 Role of lipid nanodomains for inhibitory FcγRIIb function
Spiegel, F.; Trollmann, M. F. W.; Kara, S.; Pöhnl, M.; Brandner, A. F.; Nimmerjahn, F. A.; Lux, A.; Böckmann, R. A.
10.1101/2023.05.09.540011 — immunology — Posted on 2023-05-12
2796 TRiPPing the sensors: The osmosensing pathway of Polycystin 2
Marquez-Nogueras, K. M.; Knutila, R. M.; Vuchkovska, V.; Kuo, I. Y.
10.1101/2023.05.09.540007 — physiology — Posted on 2023-05-12
2797 SKP2 knockout in Rb1/p53 deficient mouse models of osteosarcoma induces immune infiltration and drives a transcriptional program with a favorable prognosis
Ferrena, A.; Wang, J.; Zhang, R.; Karadal-Ferrena, B.; al-Hardan, W.; Singh, S.; Borjihan, H.; Schwartz, E.; Zhao, H.; Yang, R.; Geller, D.; Hoang, B.; Zheng, D.
10.1101/2023.05.09.540053 — cancer biology — Posted on 2023-05-12
2803 In-section Click-iT detection and super-resolution CLEM: Shedding light on nucleolar ultrastructure and S-phase progression in plants.
Franek, M.; Koptasikova, L.; Miksatko, J.; Pospisil, J.; Liebl, D.; Esner, M.; Macickova, E.; Dvorackova, M.; Fajkus, J.
10.1101/2023.05.10.540144 — plant biology — Posted on 2023-05-12
2804 Sequence-Dependent Material Properties of Biomolecular Condensates
Devarajan, D. S.; Wang, J.; Nikoubashman, A.; Kim, Y. C.; Mittal, J.
10.1101/2023.05.09.540038 — biophysics — Posted on 2023-05-12
2806 An SMR cell-cycle inhibitor inducible by a carotenoid metabolite resets root development and drought tolerance in Arabidopsis
Braat, J.; Jaonina, M.; David, P.; Leschevin, M.; Legeret, B.; D'Alessandro, S.; Beisson, F.; Havaux, M.
10.1101/2023.05.12.540478 — plant biology — Posted on 2023-05-12
2812 p53 controls choice between apoptotic and non-apoptotic death following DNA damage
Honeywell, M. E.; Isidor, M. S.; Harper, N. W.; Fontana, R. E.; Cruz-Gordillo, P.; Porto, S. A.; Fraser, C. S.; Sarosiek, K. A.; Guertin, D. A.; Spinelli, J. B.; Lee, M. J.
10.1101/2023.01.17.524444 — cell biology — Posted on 2023-05-12
2814 The MAPK/ERK channel capacity exceeds 6 bit/hour
Nalecz-Jawecki, P.; Gagliardi, P. A.; Kochanczyk, M.; Dessauges, C.; Pertz, O.; Lipniacki, T.
10.1101/2022.03.17.484713 — systems biology — Posted on 2023-05-11
2816 Molecular crosstalk between plant translation initiation complexes influences the outcome of virus infection
Zafirov, D.; Giovinazzo, N.; Lecampion, C.; Field, B.; Ducassou, J. N.; Coute, Y.; Browning, K. S.; Robaglia, C.; Gallois, J.-L.
10.1101/2023.05.12.540471 — plant biology — Posted on 2023-05-12
2820 Endoplasmic-Reticulum stress controls PIN-LIKES abundance and thereby growth adaptation
Waidmann, S.; Beziat, C.; Ferreira Da Silvia Santos, J.; Feraru, E.; Feraru, M. I.; Sun, L.; Noura, S.; Boutte, Y.; Kleine-Vehn, J.
10.1101/2023.05.12.540474 — plant biology — Posted on 2023-05-12
2821 Checkpoint activation by Spd1: a competition-based system relying on tandem disordered PCNA binding motifs
Olsen, J. G.; Prestel, A.; Kassem, N.; Broendum, S. S.; Shamim, H. M.; Simonsen, S.; Grysbaek, M.; Mortensen, J.; Rytkjaer, L. L.; Haxholm, G. W.; Marabini, R.; Carr, A.; Crehuet, R.; Nielsen, O.; Kragelund, B. B.
10.1101/2023.05.11.540346 — biophysics — Posted on 2023-05-12
2826 Lipid-anchored Proteasomes Control Membrane Protein Homeostasis
Zhang, R.; Pan, S.; Zheng, S.; Liao, Q.; Jiang, Z.; Wang, D.; Li, X.; Hu, A.; Li, X.; Zhu, Y.; Shen, X.; Zhang, X.; Huang, L.; Lei, J.; Zhong, S.; Wang, X.; Huang, L.; Shen, L.; Song, B.-L.; Zhao, J.; Wang, Z.; Yang, B.; Guo, X.
10.1101/2023.05.12.540509 — biochemistry — Posted on 2023-05-12
2832 Clinical, socio-demographic, and parental correlates of early autism traits in a community cohort
Gale-Grant, O.; Chew, A.; Falconer, S.; Franca, L. G. S.; Fenn-Moltu, S.; Hadaya, L.; Harper, N.; Ciarrusta, J.; Charman, T.; Murphy, D.; Arichi, T.; McAlonan, G.; Nosarti, C.; Edwards, D.; Batalle, D.
10.1101/2022.09.26.508121 — neuroscience — Posted on 2023-05-12
2833 Tetrameric UvrD helicase is located at the E. coli replisome due to frequent replication blocks
Wollman, A. J.; Syeda, A.; Howard, J.; Payne-Dwyer, A.; Leech, A.; Guy, C.; McGlynn, P.; Hawkins, M.; Leake, M. C.
10.1101/2021.02.22.432310 — biophysics — Posted on 2023-05-12
2834 Human hnRNPA1 reorganizes telomere-bound Replication Protein A
Granger, S. L.; Sharma, R.; Kaushik, V.; Razzaghi, M.; Honda, M.; Bhat, D. S.; Wlodarski, M.; Antony, E.; Spies, M.
10.1101/2023.05.09.540056 — biophysics — Posted on 2023-05-12
2835 Broad and Durable Humoral Responses Following Single Hydrogel Immunization of SARS-CoV-2 Subunit Vaccine
Ou, B. S.; Saouaf, O. M.; Yan, J.; Bruun, T. U. J.; Baillet, J.; Zhou, X.; King, N. P.; Appel, E.
10.1101/2022.12.12.520166 — bioengineering — Posted on 2023-05-12
2836 One-shot design elevates functional expression levels of a voltage-gated potassium channel
Weinstein, J. J.; Saikia, C.; Karbat, I.; Goldenzweig, A.; Reuveny, E.; Fleishman, S. J.
10.1101/2022.12.28.522065 — biochemistry — Posted on 2023-05-12
2837 Gene expression genetics of the striatum of Diversity Outbred mice
Philip, V.; He, H.; Saul, M. C.; Dickson, P. E.; Bubier, J. A.; Chesler, E. J.
10.1101/2023.05.11.540390 — genetics — Posted on 2023-05-12
2838 When Do Visual Category Representations Emerge in Infants' Brains?
Yan, X.; Tung, S.; Fascendini, B.; Chen, Y. D.; Norcia, A. M.; Grill-Spector, K.
10.1101/2023.05.11.539934 — neuroscience — Posted on 2023-05-12
2840 Phase transition of maternal RNAs during vertebrate oocyte-to-embryo transition
Hwang, H.; Chen, S.; Ma, M.; Divyanshi, ; Fan, H.-C.; Borwick, E.; Böke, E.; Mei, W.; Yang, J.
10.1101/2023.05.11.540463 — developmental biology — Posted on 2023-05-12
2841 Phase separation of Treacle is indispensable for ribosomal transcription and DNA repair.
Velichko, A. K.; Kovina, A. P.; Luzhin, A. V.; Petrova, N. V.; Deriglazov, D. A.; Kazakov, E. P.; Kireev, I. I.; Shender, V. O.; Arapidi, G. P.; Razin, S. V.; Kantidze, O. L.
10.1101/2023.05.11.540311 — cell biology — Posted on 2023-05-12
2843 Does ipsilateral remapping following hand loss impact motor control of the intact hand?
Tucciarelli, R.; Ejaz, N.; Wesselink, D. B.; Kolli, V.; Hodgetts, C. J.; Diedrichsen, J.; Makin, T.
10.1101/2023.04.19.537443 — neuroscience — Posted on 2023-05-12
2845 AT7867 promotes pancreatic progenitor differentiation of human iPSCs and accelerates diabetes reversal
Cuesta-Gomez, N.; Verhoeff, K.; Dadheech, N.; Pawlick, R.; Marfil-Garza, B.; Razavy, H.; Shapiro, J. A.
10.1101/2023.05.11.538780 — developmental biology — Posted on 2023-05-12
2847 Clustering Protein Binding Pockets and Identifying Potential Drug Interactions: A Novel Ligand-based Featurization Method
Stevenson, G. A.; Kirshner, D.; Bennion, B. J.; Yang, Y.; Zhang, X.; Zemla, A.; Torres, M. W.; Epstein, A.; Jones, D.; Kim, H.; Bennett, W. F. D.; Wong, S.; Allen, J. E.; Lightstone, F. C.
10.1101/2023.05.11.538979 — synthetic biology — Posted on 2023-05-11
2848 Discovery and Validation of Context-Dependent Synthetic Mammalian Promoters
Zahm, A. M.; Owens, W. S.; Himes, S. R.; Rondem, K. E.; Fallon, B. S.; Gormick, A. N.; Bloom, J. S.; Kosuri, S.; Chan, H.; English, J. G.
10.1101/2023.05.11.539703 — synthetic biology — Posted on 2023-05-11
2849 Improving xylose consumption in Rhodotorula toruloides through heterologous expression of xylose reductase and xylulokinase
de Oliveira, P. M.; Pinheiro, M. J.; De Biaggi, J. S.; Tsitserin, A.; Tammekivi, E.; Herodes, K.; Bonturi, N.; Lahtvee, P.-J.
10.1101/2023.05.10.540254 — synthetic biology — Posted on 2023-05-11
2853 Nuclear cytoglobin associates with HMGB2 and regulates DNA damage and genome-wide transcriptional output in the vasculature
Mathai, C.; Jourd'heuil, F.; Pham, L. G. C.; Gilliard, K.; Howard, D.; Balnis, J.; Jaitovich, A.; Chittur, S.; Riley, M.; Peredo-Wende, R.; Ibrahim, A.; Shin, S.; Barroso, M.; Barra, J.; Shishkova, E.; Coon, J.; Lopez Soler, R.; Jourd'heuil, D.
10.1101/2023.05.10.540045 — cell biology — Posted on 2023-05-11
2854 Loss of Skeletal Muscle Pyruvate Dehydrogenase Induces Lactic Acidosis and Adaptive Anaplerotic Compensation via Pyruvate-Alanine Cycling and Glutaminolysis
Gopal, K.; Abdualkader, A. M.; Li, X.; Greenwell, A. A.; Karwi, Q. G.; Saed, C.; Uddin, G. M.; Darwesh, A. M.; Jamieson, K. L.; Altamimi, T. R.; Kim, R.; Eaton, F.; Seubert, J. M.; Lopaschuk, G. D.; Ussher, J. R.; Al Batran, R.
10.1101/2023.05.10.540277 — cell biology — Posted on 2023-05-11
2856 Defining a core configuration for human centromeres during mitosis
Gupta, A. S.; Seidel, C.; Tsuchiya, D.; McKinney, S. A.; Yu, Z.; Smith, S. E.; Unruh, J.; Gerton, J.
10.1101/2023.05.10.539634 — cell biology — Posted on 2023-05-12
2859 CLEM-Reg: An automated point cloud based registration algorithm for correlative light and volume electron microscopy
Krentzel, D.; Elphick, M.; Domart, M.-C.; Peddie, C. J.; Laine, R. F.; Henriques, R.; Collinson, L. M.; Jones, M. L.
10.1101/2023.05.11.540445 — cell biology — Posted on 2023-05-12
2861 Enhlink infers distal and context-specific enhancer-promoter linkages
Poirion, O. B.; Zuo, W.; Spruce, C.; Daigle, S. L.; Olson, A.; Skelly, D. A.; Chesler, E. J.; Baker, C. L.; White, B. S.
10.1101/2023.05.11.540453 — bioinformatics — Posted on 2023-05-11
2865 Upregulated pexophagy limits the capacity of selective autophagy
Germain, K.; So, R. W. L.; Watts, J.; Bandsma, R. H. J.; Kim, P. K.
10.1101/2023.05.10.540213 — cell biology — Posted on 2023-05-11
2867 A Ciliary SMOOTHENED-GRK2-PKA Signaling Pathway Initiates Hedgehog Signal Transduction
Walker, M. F.; Zhang, J.; Steiner, W.; Ku, P.-I.; Zhu, J.-F.; Michaelson, Z.; Yen, Y.-C.; Long, A. B.; Casey, M. J.; Poddar, A.; Nelson, I. B.; Arveseth, C. D.; Nagel, F.; Clough, R.; LaPotin, S.; Kwan, K. M.; Schulz, S.; Stewart, R. A.; Tesmer, J. J. G.; Caspary, T.; Subramanian, R.; Ge, X.; Myers, B. R.
10.1101/2023.05.10.540226 — cell biology — Posted on 2023-05-11
2869 Neural Correlates and Reinstatement of Recent and Remote Memory: A Comparison Between Children and Young Adults
Schommartz, I.; Lembcke, P. F.; Ortiz-Tudela, J.; Bauer, M.; Kaindl, A. M.; Buss, C.; Shing, Y. L.
10.1101/2023.05.11.540422 — neuroscience — Posted on 2023-05-11
2872 Mapping cells through time and space with moscot
Klein, D.; Palla, G.; Lange, M.; Klein, M.; Piran, Z.; Gander, M.; Meng-Papaxanthos, L.; Sterr, M.; Bastidas-Ponce, A.; Tarquis-Medina, M.; Lickert, H.; Bakhti, M.; Nitzan, M.; Cuturi, M.; Theis, F. J.
10.1101/2023.05.11.540374 — bioinformatics — Posted on 2023-05-11
2877 Circadian PERIOD complex regulates TC-DSB repair through anchoring to the nuclear envelope
Le Bozec, B.; Guitton-Sert, L.; Collins, S.; Rocher, V.; Guillou, E.; Payrault, C.; Arnould, C.; Guenole, A.; Aguirrebengoa, M.; Finoux, A.-L.; Mangeat, T.; Puget, N.; Legube, G.
10.1101/2023.05.11.540338 — molecular biology — Posted on 2023-05-11
2878 Multi-omics analysis of a Bacteroides fragilis isolate from an ulcerative colitis patient defines genetic determinants of fitness in bile
Fiebig, A.; Schnizlein, M.; Pena-Rivera, S.; Trigodet, F.; Dubey, A.; Hennessy, M.; Basu, A.; Pott, S.; Dalal, S.; Rubin, D.; Sogin, M.; Eren, A. M.; Chang, E.; Crosson, S.
10.1101/2023.05.11.540287 — microbiology — Posted on 2023-05-11
2879 Visualizing and identifying selfish bacteria: a hunting guide
Reintjes, G.; Giljan, G. C.; Fuchs, B. M.; Arnosti, C.; Amann, R.
10.1101/2023.05.10.540300 — microbiology — Posted on 2023-05-11
2881 Local compression of the root in a microfluidic device triggers a calcium signal
Audemar, V.; Guerringue, Y.; Frederick, J.; Melogno, I.; Vinet, P.; Babataheri, A.; Legue;, V.; Thomine, S.; Frachisse, J.-M.
10.1101/2023.05.11.540308 — plant biology — Posted on 2023-05-11
2882 The NPH3-domain protein NRL5 is a plant specific type of GTPase essential for drought resistance
UPADHYAY-TIWARI, N.; Huang, X.-J.; Lee, Y.-C.; Singh, S. K.; Hsu, C.-C.; Huang, S.-S.; Verslues, P. E.
10.1101/2023.05.10.540297 — plant biology — Posted on 2023-05-11
2884 DNA methylation responses to stress across different plant species
Van Antro, M.; Ivanovic, S.; Postuma, M.; McIntyre, L.; van der Putten, W.; Vergeer, P.; Verhoeven, K.
10.1101/2023.05.10.540154 — plant biology — Posted on 2023-05-11
2886 Transition to self-compatibility associated with dominant S-allele in a diploid Siberian progenitor of allotetraploid Arabidopsis kamchatica revealed by Arabidopsis lyrata genomes
Kolesnikova, U.; Scott, A. D.; Van de Velde, J. D.; Burns, R.; Tikhomirov, N. P.; Pfordt, U.; Clarke, A. C.; Yant, L.; Seregin, A. P.; Vekemans, X.; Laurent, S.; Novikova, P. Y.
10.1101/2022.06.24.497443 — plant biology — Posted on 2023-05-11
2892 Exposing the molecular heterogeneity of glycosylated biotherapeutics
Schachner, L. F.; Mullen, C.; Phung, W.; Hinkle, J. D.; Beardsley, M. I.; Bentley, T.; Day, P.; Tsai, C.; Sukumaran, S.; Baginski, T.; DiCara, D.; Agard, N.; Masureel, M.; Gober, J.; ElSohly, A.; Syka, J. E. P.; Huguet, R.; Marty, M. T.; Sandoval, W.
10.1101/2023.05.10.540271 — biochemistry — Posted on 2023-05-11
2893 Electron transport inhibition increases cellular dependence on purine transport and salvage
Wu, Z.; Bezwada, D.; Harris, R. C.; Pan, C.; Nguyen, P. T.; Faubert, B.; Cai, L.; Cai, F.; Vu, H. S.; Chen, H.; Martin-Sandoval, M.; Do, D.; Gu, W.; Zhang, Y.; Ko, B.; Brooks, B.; Kelekar, S.; Zhang, Y.; Zacharias, L. G.; Oaxaca, K. C.; Mathews, T. P.; Garcia-Bermudez, J.; Ni, M.; DeBerardinis, R. J.
10.1101/2023.05.11.540429 — biochemistry — Posted on 2023-05-11
2894 Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex
Elkholi, I. E.; Boulais, J.; Thibault, M.-P.; Phan, H.-D.; Robert, A.; Lai, L. B.; Faubert, D.; Smith, M. J.; Gopalan, V.; Cote, J.-F.
10.1101/2023.05.11.540416 — biochemistry — Posted on 2023-05-11
2895 De novo distillation of thermodynamic affinity from deep learning regulatory sequence models of in vivo protein-DNA binding
Alexandari, A. M.; Horton, C. A.; Shrikumar, A.; Shah, N.; Li, E.; Weilert, M.; Pufall, M. A.; Zeitlinger, J.; Fordyce, P. M.; Kundaje, A.
10.1101/2023.05.11.540401 — genomics — Posted on 2023-05-11
2897 Torsion of the heart tube by shortage of progenitor cells : identification of Greb1l as a genetic determinant of criss-cross heart in mice
Bernheim, S.; Borgel, A.; Le Garrec, J. F.; Perthame, E.; Desgrange, A.; Krezel, W.; Raimondi, F.; Bonnet, D.; Houyel, L.; Meilhac, S.
10.1101/2023.05.11.540418 — developmental biology — Posted on 2023-05-11
2898 Transcript errors generate a continuous stream of amyloid and prion-like proteins in human cells
Chung, C.; Kou, Y.; Shemtov, S. `; Verheijen, B. M.; Flores, I.; Love, K.; del Dosso, A.; Thorwald, M. A.; Liu, Y.; Toney, R. G.; Carrillo, L.; Nguyen, M. M.; Biao, H.; Jin, Y.; Jauregui, A. M.; Quiroz, J. D.; Moore, D. L.; Simpson, S.; Thomas, K.; Coba, M.; Li, Z.; Benayoun, B. A.; Rosenthal, J.; Kennedy, S. R.; Quadrato, G.; Gout, J.-F.; Chen, L.; Vermulst, M.
10.1101/2023.05.11.540433 — molecular biology — Posted on 2023-05-11
2900 L. pneumophila resists its self-harming metabolite HGA via secreted factors and collective peroxide scavenging
Holland, M.; Farinella, D. N.; Cruz-Lorenzo, E.; Laubscher, M. I.; Doakes, D. A.; Ramos, M. A.; Kubota, N.; Levin, T.
10.1101/2023.05.11.540380 — microbiology — Posted on 2023-05-11
2902 RAD51-mediated R-loop formation acts to repair transcription-associated DNA breaks driving antigenic variation in Trypanosoma brucei
Girasol, M. J.; Krasilnikova, M.; Marques, C. A.; Damasceno, J. D.; Lapsley, C.; Lemgruber, L.; Burchmore, R.; Beraldi, D.; Carruthers, R.; Briggs, E. M.; McCulloch, R.
10.1101/2023.05.11.540369 — microbiology — Posted on 2023-05-11
2904 A PI(3,4,5)P3-dependent allosteric switch controls antigenic variation in trypanosomes
Touray, A. O.; Rajesh, R.; Isebe, T.; Sternlieb, T.; Loock, M.; Kutova, O.; Cestari, I.
10.1101/2023.05.11.540368 — microbiology — Posted on 2023-05-11
2906 Age-dependent Powassan Virus Lethality and Neuropathogenesis in Mice
Mladinich, M.; Himmler, G.; Conde, J. N.; Gorbunova, E.; Schutt, W. R.; Tsirka, S.; Kim, H. K.; Mackow, E. R.
10.1101/2023.05.11.540417 — microbiology — Posted on 2023-05-11
2907 Guild and Niche Determination Enable Targeted Alteration of the Microbiome
Moyne, O.; Al-Bassam, M. M.; Lieng, C.; Thiruppathy, D.; Norton, G. J.; Kumar, M.; Haddad, E.; Zaramela, L. S.; Zengler, K.
10.1101/2023.05.11.540389 — microbiology — Posted on 2023-05-11
2908 Phage activity against Staphylococcus aureus is impaired in plasma and synovial fluid.
Mutti, M.; Saez Moreno, D.; Restrepo-Cordoba, M.; Visram, Z.; Resch, G.; Corsini, L.
10.1101/2023.05.11.540358 — microbiology — Posted on 2023-05-11
2909 Within-host rhinovirus evolution in upper and lower respiratory tract highlights capsid variability and mutation-independent compartmentalization
Makhsous, N.; Goya, S.; Avendano, C.; Rupp, J.; Kuypers, J.; Jerome, K. R.; Boeckh, M.; Waghmare, A.; Greninger, A. L.
10.1101/2023.05.11.540440 — microbiology — Posted on 2023-05-11
2910 Temporal dynamics of gut microbiomes in non-industrialized urban Amazonia
Schaan, A. P.; Vidal, A.; Zhang, A.-N.; Poyet, M.; Alm, E. J.; Groussin, M.; Ribeiro-dos-Santos, A.
10.1101/2023.05.11.540371 — microbiology — Posted on 2023-05-11
2912 Metabolic alterations unravel the materno fetal immune responses with disease severity in pregnant women infected with SARS-CoV-2
Hora, S.; Pahwa, P.; Siddqui, H.; Saxena, A.; Kashyap, M.; Sevak, J. K.; Singh, R.; Javed, M.; Yadav, P.; Kale, P.; Ramakrishna, G.; Rathore, A.; Maras, J. S.; Tyagi, S.; Sarin, S. K.; Trehanpati, N.
10.1101/2023.05.10.540101 — immunology — Posted on 2023-05-11
2914 Development and Biophysical Characterization of a Humanized FSH-Blocking Monoclonal Antibody Therapeutic Formulated at an Ultra-High Concentration
Rojekar, S.; Pallapati, A. R.; Gimenez-Roig, J.; Korkmaz, F.; Sultana, F.; Sant, D.; Haeck, C. M.; Macdonald, A.; Kim, S.-M.; Rosen, C. J.; Barak, O.; Meseck, M.; Caminis, J.; Lizneva, D.; Yuen, T.; Zaidi, M.
10.1101/2023.05.11.540323 — bioengineering — Posted on 2023-05-11
2915 Small Molecule Activators of B56-PP2A Restore 4E-BP Expression and Function to Suppress Cap-dependent Translation in Cancer Cells
Lum, M. A.; Jonas-Breckenridge, K. A.; Black, A. R.; Woods, N. T.; O'Connor, C. M.; Avelar, R. A.; DiFeo, A.; Narla, G.; Black, J. D.
10.1101/2022.05.24.493272 — cancer biology — Posted on 2023-05-11
2917 Genetic manipulation of candidate phyla radiation bacteria provides functional insights into microbial dark matter
Wang, Y.; Gallagher, L. A.; Andrade, P. A.; Liu, A.; Humphreys, I. R.; Turkarslan, S.; Cutler, K. J.; Arrieta-Ortiz, M. L.; Li, Y.; Radey, M. C.; McLean, J. S.; Cong, Q.; Baker, D.; Baliga, N. S.; Peterson, S. B.; Mougous, J. D.
10.1101/2023.05.02.539146 — microbiology — Posted on 2023-05-11
2919 Direct prediction of intrinsically disordered protein conformational properties from sequence
Lotthammer, J. M.; Ginell, G. M.; Griffith, D.; Emenecker, R. J.; Holehouse, A. S.
10.1101/2023.05.08.539824 — biophysics — Posted on 2023-05-11
2920 Near-chromosome level genome assembly of devil firefish, Pterois miles
Kitsoulis, C. V.; Papadogiannis, V.; Kristoffersen, J. B.; Kaitetzidou, E.; Sterioti, A.; Tsigenopoulos, C. S.; Manousaki, T.
10.1101/2023.01.10.523469 — genomics — Posted on 2023-05-11
2921 Histone variants shape the chromatin states in Arabidopsis
Jamge, B.; Lorkovic, Z. J.; Axelsson, E.; Osakabe, A.; Shukla, V.; Yelagandula, R.; Akimcheva, S.; Khuen, A. L.; Berger, F.
10.1101/2023.03.08.531698 — genomics — Posted on 2023-05-11
2922 Purkinje-Enriched snRNA-seq in SCA7 Cerebellum Reveals Zebrin Identity Loss as a Central Feature of Polyglutamine Ataxias
Bartelt, L. C.; Switonski, P. M.; Adamek, G.; Carvalho, J.; Duvick, L. A.; Jarrah, S. I.; McLoughlin, H. S.; Scoles, D. R.; Pulst, S. M.; Orr, H. T.; Hull, C.; Lowe, C. B.; La Spada, A. R.
10.1101/2023.03.19.533345 — genomics — Posted on 2023-05-11
2924 Transcriptomic responses of sponge holobionts to in situ, seasonal anoxia and hypoxia
Strehlow, B. W.; Schuster, A.; Francis, W. R.; Eckford-Soper, L.; Kraft, B.; McAllen, R.; Nielsen, R.; Mandrup, S.; Canfield, D. E.
10.1101/2023.02.27.530229 — ecology — Posted on 2023-05-11
2925 Effects of fire regime on the bird community in an Amazonian savanna
Coelho, L. A.; Ritter, C. d.; Lima, A.; Cintra, R.; Magnusson, W.; Sanaiotti, T.
10.1101/2022.08.01.502386 — ecology — Posted on 2023-05-11
2926 iFlpMosaics: A method for the ratiometric induction and high-throughput comparative analysis of mutant and wildtype cells
Garcia-Gonzalez, I.; Gambera, S.; Regano, A.; Rocha, S. F.; Garcia-Ortega, L.; Lytvyn, M.; Sanchez-Munoz, M. S.; Garcia-Cabero, A.; Zagorac, I.; Luo, W.; Fernandez-Chacon, M.; Casquero-Garcia, V.; Lunella, F. F.; Benedito, R.
10.1101/2023.05.09.540000 — cell biology — Posted on 2023-05-11
2927 Single-nucleus analysis characterizes non-enhancing region of recurrent high-grade glioma
Patel, K. S.; Tessema, K. K.; Kawaguchi, R.; Alvarado, A. G.; Muthukrishnan, S. D. D.; Hagiwara, A.; Swarup, V.; Liau, L. M.; Wang, A. C.; Yong, W.; Geschwind, D.; Nakano, I.; Goldman, S.; Everson, R.; Ellingson, B.; Kornblum, H.
10.1101/2022.10.10.511639 — neuroscience — Posted on 2023-05-11
2928 Universal method for the gentle isolation of intact microvessels from frozen tissue: a multiomic investigation into the neurovasculature
Wakid, M.; Almeida, D.; Aouabed, Z.; Rahimian, R.; Davoli, M. A.; Yerko, V.; Leonova-Erko, E.; Richard, V.; Zahedi, R.; Borchers, C.; Turecki, G.; Mechawar, N.
10.1101/2023.05.10.540076 — neuroscience — Posted on 2023-05-11
2930 CDK7 is a Novel Therapeutic Vulnerability in Fibrolamellar Carcinoma
Nukaya, M.; Cafferty, C.; Zahed, K.; Yun, I.; Al-Adra, D. P.; Kazim, N. A.; Farghli, A. R.; Chan, M.; Kratz, J. D.; Berres, M. E.; Yen, A.; Gujral, T.; Sethupathy, P.; Bradfield, C. A.; Ronnekleiv-Kelly, S. M.
10.1101/2023.04.22.537934 — cancer biology — Posted on 2023-05-11
2931 Interplay between VSD, pore and membrane lipids in electromechanical coupling in HCN channels
Elbahnsi, A.; Cowgill, J.; Burtscher, V.; Wedemann, L.; Zeckey, L.; Chanda, B.; Delemotte, L.
10.1101/2022.05.20.492765 — biophysics — Posted on 2023-05-11
2933 DMRT1 is a Testis Determining Gene in Rabbits and is Also Essential for Female Fertility
Dujardin, E.; Andre, M.; Dewaele, A.; Mandon-Pepin, B.; Poulat, F.; Frambourg, A.; Thepot, D.; Jouneau, L.; Jolivet, G.; Pailhoux, E.; Pannetier, M.
10.1101/2023.01.13.523925 — developmental biology — Posted on 2023-05-11
2935 Upregulated NF-κB pathway proteins may underlie APOE4 associated astrocyte phenotypes in sporadic Alzheimer's disease
Pryce Roberts, A.; Dec, K.; McAllister, B.; Tyrrell, V.; O'Donnell, V. B.; Harwood, A. J.; Williams, J.
10.1101/2023.04.19.537428 — cell biology — Posted on 2023-05-11
2939 Goal-seeking compresses neural codes for space in the human hippocampus and orbitofrontal cortex
Muhle-Karbe, P. S.; Sheahan, H.; Pezzulo, G.; Spiers, H. J.; Chien, S.; Schuck, N. W.; Summerfield, C.
10.1101/2023.01.12.523762 — neuroscience — Posted on 2023-05-11
2940 A spatial code for temporal cues is necessary for sensory learning
Bagur, S.; Bourg, J.; Kempf, A.; Tarpin, T.; Bergaoui, K.; Guo, Y.; Ceballo, S.; Schwenkgrub, J.; Verdier, A.; Puel, J.-L.; Bourien, J.; Bathellier, B.
10.1101/2022.12.14.520391 — neuroscience — Posted on 2023-05-11
2943 A novel enhancer-AAV approach selectively targeting dentate granule cells
Banks, E.; Gutekunst, C.-A.; Vargish, G. A.; Eaton, A.; Pelkey, K. A.; McBain, C. J.; Zheng, J. Q.; Olah, V. J.; Rowan, M.
10.1101/2023.02.03.527045 — neuroscience — Posted on 2023-05-11
2944 Deficient synaptic neurotransmission results in a persistent sleep-like cortical activity across vigilance states in mice
Guillaumin, M. C. C.; Harding, C. D.; Krone, L. B.; Yamagata, T.; Kahn, M. C.; Blanco-Duque, C.; Banks, G. T.; Nolan, P. M.; Peirson, S. N.; Vyazovskiy, V. V.
10.1101/2023.05.11.540034 — neuroscience — Posted on 2023-05-11
2945 Home security cameras as a tool for behavior observations and science equity
Goolsby, B. C.; Fischer, M.-T.; Pareja-Mejia, D.; Lewis, A. R.; Raboisson, G.; O'Connell, L. A.
10.1101/2023.04.17.537238 — animal behavior and cognition — Posted on 2023-05-11
2946 Enhanced capillary pumping using open-channel capillary trees with integrated paper pads
Tokihiro, J. C.; Tu, W.-c.; Berthier, J.; Lee, J. J.; Dostie, A. M.; Khor, J. W.; Theberge, A. B.; Berthier, E.
10.1101/2022.07.15.500252 — bioengineering — Posted on 2023-05-11
2949 The influence of the larval microbiome on susceptibility to Zika virus is mosquito genotype dependent
Accoti, A.; Multini, L. C.; Diouf, B.; Becker, M.; Vulcan, J.; Sylla, M.; Yap, D. a. Y.; Khanipov, K.; Weaver, S.; Diallo, M.; Gaye, A.; Dickson, L. B.
10.1101/2023.05.10.540191 — microbiology — Posted on 2023-05-11
2950 FUME-TCRseq: Sensitive and accurate sequencing of the T-cell receptor from limited input of degraded RNA
Baker, A.-M.; Nageswaran, G.; Nenclares, P.; Ronel, T.; Smith, K.; Kimberley, C.; Lacle, M. M.; Bhide, S.; Harrington, K. J.; Melcher, A.; Rodriguez-Justo, M.; Chain, B.; Graham, T. A.
10.1101/2023.04.24.538037 — immunology — Posted on 2023-05-11
2952 Enhancing Collaborative Neuroimaging Research: Introducing COINSTAC Vaults for Federated Analysis and Reproducibility
Martin, D.; Basodi, S.; Panta, S.; Rootes-Murdy, K.; Prae, P.; Sarwate, A.; Kelly, R.; Romero, J.; T Baker, B.; Gazula, H.; Bockholt, J.; Turner, J.; B Esper Franco, N.; R Franco, A.; Plis, S.; Calhoun, V.
10.1101/2023.05.08.539852 — neuroscience — Posted on 2023-05-11
2955 An Excitatory Projection from the Basal Forebrain to the Ventral Tegmental Area Underlying Anorexia-like Phenotypes
Cai, J.; Xu, Y.; Jiang, Z.; Jiang, Y.; Young, C.; Li, H.; Otiz-Guzman, J.; Zhuo, Y.; Li, Y.; Xu, Y.; Arenkiel, B. R.; Tong, Q.
10.1101/2023.05.05.539422 — neuroscience — Posted on 2023-05-11
2956 Genetic and dietary modulators of the inflammatory response in the gastro-intestinal tract of the BXD mouse genetic reference population
Li, X.; Morel, J.-D.; Benegiamo, G.; Poisson, J.; Bachmann, A.; Rapin, A.; Sulc, J.; Williams, E. G.; Perino, A.; Schoonjans, K.; Bou Sleiman, M. S.; Auwerx, J.
10.1101/2023.03.22.533818 — systems biology — Posted on 2023-05-11
2957 Glioblastoma extracellular vesicles influence glial cell hyaluronic acid deposition to promote invasiveness
Norman, J. C.; Koessinger, D.; Novo, D.; Birch, J.; Mitchell, L.; Moore, M.; Zerbst, D.; Chalmers, A.; Koessinger, A.; Stevenson, K.; Nielson, M.
10.1101/2022.02.11.480036 — cancer biology — Posted on 2023-05-11
2960 Like mother, like daughter? Phenotypic plasticity, environmental covariation, and heritability of size in a parthenogenetic wasp
Tovar, A.; Monahan, S.; Kristan, A.; Welch, W.; Dettmers, R.; Arce, C.; Buck, T.; Ruben, M.; Rothenberg, A.; Saisho, R.; Cartmill, R.; Skaggs, T.; Reyes, R.; Lee, M.; Obrycki, J. J.; Kristan, W.; Sethuraman, A.
10.1101/2022.12.02.518902 — evolutionary biology — Posted on 2023-05-11
2963 Sensitivity-enhanced magnetic resonance reveals hydrogen intermediates during active -hydrogenase catalysis
Kaltschnee, L.; Pravdivtsev, A. N.; Gehl, M.; Huang, G.; Stoychev, G. L.; Riplinger, C.; Keitel, M.; Neese, F.; Hövener, J.-B.; Auer, A. A.; Griesinger, C.; Shima, S.; Glöggler, S.
10.1101/2023.05.10.540199 — biophysics — Posted on 2023-05-11
2965 Ariadne: Synthetic Long Read Deconvolution Using Assembly Graphs
Mak, L.; Meleshko, D.; Danko, D. C.; Barakzai, W. N.; Maharjan, S.; Belchikov, N.; Hajirasouliha, I.
10.1101/2021.05.09.443255 — genomics — Posted on 2023-05-11
2973 Anatomical registration of intracranial electrodes. Robust model-based localization and deformable smooth brain-shift compensation methods
Blenkmann, A. O.; Leske, S. L.; Llorens, A.; Lin, J. J.; Chang, E.; Brunner, P.; Schalk, G.; Ivanovic, J.; Larsson, P. G.; Knight, R. T.; Endestad, T.; Solbakk, A.-K.
10.1101/2023.05.08.539503 — bioinformatics — Posted on 2023-05-11
2974 A protease and a lipoprotein jointly modulate the conserved ExoR-ExoS-ChvI signaling pathway critical in Sinorhizobium meliloti for symbiosis with legume hosts
Bustamante, J. A.; Ceron, J. S.; Gao, I. T.; Ramirez, H. A.; Aviles, M. V.; Bet Adam, D.; Brice, J. R.; Cuellar, R.; Dockery, E.; Jabagat, M. K.; Karp, D. G.; Lau, J. K.-O.; Li, S.; Lopez-Magana, R.; Moore, R. R.; Morin, B. K. R.; Nzongo, J.; Rezaeihaghighi, Y.; Sapienza-Martinez, J.; Tran, T. T. K.; Huang, Z.; Duthoy, A. J.; Barnett, M. J.; Long, S.; Chen, J. C.
10.1101/2023.05.09.539952 — microbiology — Posted on 2023-05-11
2978 A wound-induced differentiation trajectory for neurons
Hulett, R. E.; Gehrke, A. R.; Gompers, A.; Rivera-Lopez, C.; Srivastava, M.
10.1101/2023.05.10.540286 — developmental biology — Posted on 2023-05-11
2980 Neuronal lipofuscinosis caused by Kufs disease/CLN4 DNAJC5 mutations but not by a CSPα/DNAJC5 deficiency
Lopez-Begines, S.; Lavado-Roldan, A.; Mesa-Cruz, C.; Mavillard, F.; Borjini, N.; Wiersma, V.; Aguado, C.; Lujan, R.; Scheper, W.; Nieto-Gonzalez, J. L.; Fernandez-Chacon, R.
10.1101/2023.05.10.540177 — neuroscience — Posted on 2023-05-11
2981 Syndecan-1 as specific cerebrospinal fluid biomarker of multiple sclerosis
Hinsinger, G.; Du Trieu de Terdonck, L.; Urbach, S.; Salvetat, N.; Rival, M.; Galoppin, M.; Ripoll, C.; Cezar, R.; Laurent-Chabalier, S.; Demattei, C.; Agherbi, H.; Castelnovo, G.; Lehmann, S.; Rigau, V.; Marin, P.; Thouvenot, E.
10.1101/2023.05.10.540204 — neuroscience — Posted on 2023-05-11
2982 Universal method for the gentle isolation of intact microvessels from frozen tissue: a multiomic investigation into the neurovasculature
Wakid, M.; Almeida, D.; Aouabed, Z.; Rahimian, R.; Davoli, M. A.; Yerko, V.; Leonova-Erko, E.; Richard, V.; Zahedi, R.; Turecki, G.; Mechawar, N.
10.1101/2023.05.10.540076 — neuroscience — Posted on 2023-05-11
2983 Enhanced mitochondrial fusion during a critical period of synaptic plasticity in adult-born neurons
Kochan, S. M. V.; Malo, M. C.; Jevtic, M.; Jahn, H. M.; Wani, G. A.; Gaedke, F.; Schaeffner, I.; Lie, D. C.; Schauss, A.; Bergami, M.
10.1101/2023.05.11.540324 — neuroscience — Posted on 2023-05-11
2985 Lactobacillus maintains IFNγ homeostasis to promote behavioral stress resilience.
Merchak, A. R.; Wachamo, S.; Brown, L. C.; Takur, A.; Moreau, G. B.; Brown, R. M.; Rivet-Noor, C.; Raghavan, T. P.; Gaultier, A.
10.1101/2023.05.10.540223 — neuroscience — Posted on 2023-05-11
2987 Ketosis regulates K+ ion channels, strengthening brain-wide signaling disrupted by age.
van Nieuwenhuizen, H.; Chesebro, A. G.; Polizu, C.; Clarke, K.; Strey, H. H.; Weistuch, C.; Mujica-Parodi, L. R.
10.1101/2023.05.10.540257 — neuroscience — Posted on 2023-05-11
2988 DDHD2 interacts with STXBP1 to mediate long-term memory via the generation of myristic acid
Akefe, I. O.; Matthews, B.; Saber, S. H.; Venkatesh, B. G.; Gormal, R.; Blackmore, D. G.; Sierecki, E.; Gambin, Y.; Bertran-Gonzalez, J.; Michaels, A. A.; Xue, M.; Cravatt, B. F.; Joensuu, M.; Wallis, T.; Meunier, F. A.
10.1101/2023.05.11.540316 — neuroscience — Posted on 2023-05-11
2990 Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
Tan, J. Z. A.; Jang, S. E.; Batallas-Borja, A.; Bhembre, N.; Chandra, M.; Zhang, L.; Guo, H.; Ringuet, M. T.; Widagdo, J.; Collins, B. M.; Anggono, V.
10.1101/2023.05.10.540298 — neuroscience — Posted on 2023-05-11
2991 Deficient synaptic neurotransmission results in a persistent sleep-like cortical activity across vigilance states in mice
Guillaumin, M. C. C.; Harding, C. D.; Krone, L. B.; Yamagata, T.; Kahn, M. C.; Blanco-Duque, C.; Banks, G. T.; Nolan, P. M.; Peirson, S. N.; Vyazovskiy, V. V.
10.1101/2023.05.11.540034 — neuroscience — Posted on 2023-05-11
2994 Generalized fear following acute stress is caused by change in co-transmitter identity of serotonergic neurons
Li, H.-q. L.; Jiang, W.; Ling, L.; Gupta, V.; Chen, C.; Pratelli, M.; Godavarthi, S. K.; Spitzer, N. C.
10.1101/2023.05.10.540268 — neuroscience — Posted on 2023-05-11
2995 Chondrogenic Enhancer Landscape of Limb and Axial Skeleton Development
Darbellay, F.; Ramisch, A.; Lopez-Delisle, L.; Kosicki, M.; Visel, A.; Andrey, G.
10.1101/2023.05.10.539849 — genomics — Posted on 2023-05-11
3001 Side-Chain Dynamics of the α1B-Adrenergic Receptor determined by NMR via Methyl Relaxation
Baumann, C.; Chiang, W.-C.; Valsecchi, R.; Jurt, S.; Deluigi, M.; Schuster, M.; Plueckthun, A.; Zerbe, O.
10.1101/2023.05.09.539984 — biophysics — Posted on 2023-05-10
3008 Diversity and Evolution of an Abundant ICEclc-Family of Integrative and Conjugative Elements in Pseudomonas aeruginosa
Benigno, V.; Carraro, N.; Sarton-Loheac, G.; Romano-Bertrand, S.; Blanc, D. S.; van der Meer, J. R.
10.1101/2023.05.10.540162 — microbiology — Posted on 2023-05-10
3010 Phosphoribulokinase abundance is not limiting the Calvin-Benson-Bassham cycle in Chlamydomonas reinhardtii
Boisset, N. D.; Favoino, G.; Meloni, M.; Jomat, L.; Cassier-Chauvat, C.; Zaffagnini, M.; Lemaire, S. D.; Crozet, P.
10.1101/2023.05.10.540127 — synthetic biology — Posted on 2023-05-10
3011 De novo synthesis of a conjugative system from human gut metagenomic data for targeted delivery of Cas9 antimicrobials
Hamilton, T. A.; Joris, B. R.; Shrestha, A.; Browne, T. S.; Rodrigue, S.; Karas, B. J.; Gloor, G. B.; Edgell, D. R.
10.1101/2023.05.10.540216 — synthetic biology — Posted on 2023-05-10
3013 YidC from Escherichia coli forms an ion-conducting pore upon activation by ribosomes.
Knyazev, D. G.; Winter, L.; Vogt, A.; Posch, S.; Siligan, C.; Goessweiner-Mohr, N.; Hagleitner-Ertugrul, N.; Koch, H.-G.; Pohl, P.
10.1101/2023.05.10.540180 — biophysics — Posted on 2023-05-10
3014 Elongator is a microtubule polymerase selective for poly-glutamylated tubulin
Planelles-Herrero, V. J.; Genova, M.; Bittleston, A.; McNally, K. E.; Degliesposti, G.; Magiera, M. M.; Janke, C.; Derivery, E.
10.1101/2023.05.10.540202 — biochemistry — Posted on 2023-05-10
3018 In vitro methylation of the U7 snRNP subunits Lsm11 and SmE by the PRMT5/MEP50/pICln methylosome
Yang, X.-c.; Desotell, A.; Lin, M.-H.; Paige, A. S.; Malinowska, A.; Sun, Y.; Aik, W. S.; Dadlez, M.; Tong, L.; Dominski, Z.
10.1101/2023.05.10.540203 — biochemistry — Posted on 2023-05-10
3019 At-home saliva sampling in healthy adults using CandyCollect, a lollipop-inspired device
Tu, W.-c.; McManamen, A. M.; Su, X.; Jeacopello, I.; Takezawa, M. G.; Hieber, D. L.; Hassan, G. W.; Lee, U. N.; Anana, E. V.; Locknane, M. P.; Stephenson, M. W.; Shinkawa, V. A. M.; Wald, E. R.; DeMuri, G. P.; Adams, K.; Berthier, E.; Thongpang, S.; Theberge, A. B.
10.1101/2023.01.14.524039 — biochemistry — Posted on 2023-05-10
3020 Downregulation of CYP7B1 caused by lipotoxicity associates with the progression of non-alcoholic steatohepatitis
Watanabe, Y.; Kinoshita, K.; Dumrongkulchart, N.; Sasaki, T.; Shimizu, M.; Yamauchi, Y.; Sato, R.
10.1101/2023.05.10.539979 — biochemistry — Posted on 2023-05-10
3021 Extended family with an inherited pathogenic variant in polymerase delta provides strong evidence for recessive effect of proofreading deficiency in human cells
Andrianova, M. A.; Seplyarskiy, V. B.; Terradas, M.; Sanchez-Heras, A. B.; Mur, P.; Soto, J. L.; Aiza, G.; Kondrashov, F. A.; Kondrashov, A. S.; Bazykin, G. A.; Valle, L.
10.1101/2022.07.20.500591 — genetics — Posted on 2023-05-10
3028 Molecular mechanisms for activation of the 26S proteasome
Lu, Y.; Goldberg, A.; Colson, L.; Lee, D.; Zhu, Y.; Wang, X.; Huang, L.; Chen, S.; Ouyang, Q.; Tkacik, E.
10.1101/2023.05.09.540094 — molecular biology — Posted on 2023-05-10
3029 Cardiomyocyte Targeting Peptide to Deliver Amiodarone
Zahid, M.; Gabris-Weber, B. A.; Yurko, R.; Islam, K.; Agrawal, V.; Lopuszynski, J.; Yagi, H.; Salama, G.
10.1101/2023.05.10.540206 — molecular biology — Posted on 2023-05-10
3030 SETDB1 Triple Tudor Domain Ligand, (R,R)-59, Promotes Methylation of Akt1 in Cells
Uguen, M.; Deng, Y.; Li, F.; Shell, D. J.; Norris-Drouin, J. L.; Stashko, M. A.; Ackloo, S.; Arrowsmith, C. H.; James, L. I.; Liu, P.; Pearce, K. H.; Frye, S. V.
10.1101/2023.05.10.539986 — molecular biology — Posted on 2023-05-10
3032 Predicting Blomia tropicalis allergens using a multiomics approach
Hubert, J.; Vrtala, S.; Sopko, B.; Dowd, S. E.; He, Q.; Klimov, P. B.; Harant, K.; Thalacko, P.; Erban, T.
10.1101/2023.05.10.540119 — molecular biology — Posted on 2023-05-10
3033 Genome streamlining in CPR bacteria transitioning from soil to groundwater
Chaudhari, N. M.; Perez-Carrascal, O. M.; Overholt, W. A.; Totsche, K. U.; Kuesel, K.
10.1101/2023.05.10.540099 — microbiology — Posted on 2023-05-10
3035 Novel taxonomic and functional diversity of bacteria from the upper digestive tract of chicken
Galicia, B. R.; Saenz, J. S.; Yergaliyev, T.; Roth, C.; Camarinha-Silva, A.; Seifert, J.
10.1101/2023.05.10.540237 — microbiology — Posted on 2023-05-10
3036 The influence of the larval microbiome on susceptibility to Zika virus is mosquito genotype dependent
Accoti, A.; Multini, L. C.; Diouf, B.; Becker, M.; Vulcan, J.; Sylla, M.; Yap, D. a. Y.; Khanipov, K.; Weaver, S.; Diallo, M.; Gaye, A.; Dickson, L. B.
10.1101/2023.05.10.540191 — microbiology — Posted on 2023-05-10
3039 Analysis of in-patient evolution of Escherichia coli reveals potential links to relapse of bone and joint infections
Thiriet Rupert, S.; Josse, J.; Perez Pascual, D.; Tasse, J.; Andre, C.; Abad, L.; Lebeaux, D.; Ghigo, J.-M.; Laurent, F.; Beloin, C.
10.1101/2023.05.10.540183 — microbiology — Posted on 2023-05-10
3040 Molecular motor tug-of-war regulates elongasome cell wall synthesis dynamics in Bacillus subtilis
Middlemiss, S.; Roberts, D. M.; Grimshaw, J.; Edwards, J. M.; Sun, Z.; Whitley, K. D.; Blu, T.; Strahl, H.; Holden, S.
10.1101/2023.05.10.540107 — microbiology — Posted on 2023-05-10
3044 Aberrant brain criticality as a neural basis of preclinical Alzheimer's disease
Javed, E.; Saurez-Mendez, I.; Susi, G.; Verdejo-Roman, J.; Palva, J. M.; Maestu, F.; Palva, S.
10.1101/2022.12.22.521549 — neuroscience — Posted on 2023-05-10
3045 Comprehensive proteomic analysis of JC polyomavirus-infected human astrocytes and their excreted vesicles
Oberholster, L.; Mathias, A.; Perriot, S.; Blaser, E.; Canales, M.; Jones, S.; Culebras, L.; Gimenez, M.; Kaynor, G. C.; Sapozhnik, A.; Richetin, K.; Goelz, S.; Du Pasquier, R.
10.1101/2023.04.11.536379 — neuroscience — Posted on 2023-05-10
3047 Item-specific memory reactivation during sleep supports memory consolidation in humans
Liu, J.; Xia, T.; Chen, D.; Yao, Z.; Zhu, M.; Antony, J. W.; Lee, T. M.; Hu, X.
10.1101/2023.01.25.525599 — neuroscience — Posted on 2023-05-10
3049 The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies
Yu, D. S.; Outram, M. A.; Smith, A.; McCombe, C. L.; Khambalkar, P. B.; Rima, S. A.; Sun, X.; Ma, L.; Ericsson, D. J.; Jones, D. A.; Williams, S. J.
10.1101/2021.12.14.472499 — plant biology — Posted on 2023-05-10
3055 Is tumor mutational burden predictive of response to immunotherapy?
Gurjao, C.; Tsukrov, D.; Imakaev, M.; Luquette, L. J.; Mirny, L. A.
10.1101/2020.09.03.260265 — genomics — Posted on 2023-05-10
3057 Population demographic history and evolutionary rescue: influence of a bottleneck event
Olazcuaga, L.; Lincke, B.; Delacey, S.; Durkee, L. F.; Melbourne, B. A.; Hufbauer, R. A.
10.1101/2023.01.11.523672 — evolutionary biology — Posted on 2023-05-10
3058 How density dependence, genetic erosion, and the extinction vortex impact evolutionary rescue
Nordstrom, S. W.; Hufbauer, R. A.; Olazcuaga, L.; Durkee, L. F.; Melbourne, B. A.
10.1101/2022.10.29.514126 — ecology — Posted on 2023-05-10
3059 Common scab disease: structural basis of elicitor recognition in pathogenic Streptomyces species
Kerff, F.; Jourdan, S.; Francis, I. M.; Deflandre, B.; Ribeiro Monteiro, S.; Stulanovic, N.; Loria, R.; Rigali, S.
10.1101/2023.05.10.540135 — microbiology — Posted on 2023-05-10
3060 Single-cell transcriptome landscape of circulating CD4+ T cell populations in human autoimmune diseases
Yasumizu, Y.; Takeuchi, D.; Morimoto, R.; Takeshima, Y.; Okuno, T.; Kinoshita, M.; Morita, T.; Kato, Y.; Wang, M.; Motooka, D.; Okuzaki, D.; Nakamura, Y.; Mikami, N.; Arai, M.; Zhang, X.; Kumanogoh, A.; Mochizuki, H.; Ohkura, N.; Sakaguchi, S.
10.1101/2023.05.09.540089 — immunology — Posted on 2023-05-10
3063 Squigulator: simulation of nanopore sequencing signal data with tunable noise parameters
Gamaarachchi, H.; Ferguson, J. M.; Samarakoon, H.; Liyanage, K.; Deveson, I. W.
10.1101/2023.05.09.539953 — bioinformatics — Posted on 2023-05-10
3064 Population genomics reveals extensive inbreeding and purging of mutational load in wild Amur tigers
Lan, T.; Li, H.; Zhang, L.; Shi, M.; Liu, B.; Cui, L.; Dussex, N.; Wang, Q.; Ma, Y.; Liu, D.; Kong, W.; Wang, J.; Lu, H.; Zhang, S.; Yu, J.; Wang, X.; Wu, Y.; Niu, X.; Fan, J.; Zhao, Y.; Dalen, L.; Jiang, G.; Liu, H.; Xu, Y.
10.1101/2023.05.09.539923 — genomics — Posted on 2023-05-10
3067 Identification of cytokine predominant immunosuppressive class and prognostic risk signatures in glioma
Tian, Z.; Yang, Z.; Jin, M.; Ding, R.; Wang, Y.; Chai, Y.; Wu, J.; Yang, M.; Weimin, Z.
10.1101/2023.05.09.539946 — immunology — Posted on 2023-05-10
3071 High-resolution molecular atlas of a lung tumor in 3D
Pentimalli, T. M.; Schallenberg, S.; Leon-Perinan, D.; Legnini, I.; Theurillat, I.; Thomas, G.; Boltengagen, A.; Fritzsche, S.; Nimo, J.; Ruff, L.; Dernbach, G.; Jurmeister, P.; Murphy, S.; Gregory, M.; Liang, Y.; Cordenonsi, M.; Piccolo, S.; Coscia, F.; Woehler, A.; Karaiskos, N.; Klauschen, F.; Rajewsky, N.
10.1101/2023.05.10.539644 — systems biology — Posted on 2023-05-10
3073 Dysbiosis of a leaf microbiome is caused by enzyme secretion of opportunistic Xanthomonas strains
Pfeilmeier, S.; Werz, A.; Ote, M.; Bortfeld-Miller, M.; Kirner, P.; Keppler, A.; Hemmerle, L.; Gaebelein, C. G.; Pestalozzi, C. M.; Vorholt, J. A.
10.1101/2023.05.09.539948 — plant biology — Posted on 2023-05-10
3075 Immunomodulatory Leptin Receptor+ Sympathetic Perineurial Cells Protect Against Obesity by Facilitating Neuroendocrine-Mediated Brown Adipose Tissue Thermogenesis
Haberman, E. R.; Sarker, G.; Arus, B. A.; Yilmaz-Ozcan, S.; Martinez-Sanchez, N.; Freibergerova, E.; Fernandez-Gonzalez, I.; Zentai, C.; O'Brien, C. J. O.; Grainger, D. E.; Chakarov, S.; Raimondi, A.; Iannacone, M.; Lopez, M.; Ginhoux, F.; Domingos, A. I.
10.1101/2023.05.09.539963 — physiology — Posted on 2023-05-10
3079 Raman spectra and gene expression correspondences reveal global stoichiometry conservation architecture in cells
Kamei, K.-i. F.; Kobayashi-Kirschvink, K. J.; Nozoe, T.; Nakaoka, H.; Umetani, M.; Wakamoto, Y.
10.1101/2023.05.09.539921 — genomics — Posted on 2023-05-10
3082 Birds escape the oxidative stress costs of high blood glucose levels
Vagasi, C. I.; Vincze, O.; Adamkova, M.; Kauzalova, T.; Lendvai, A. Z.; Patras, L.; Penzes, J.; Pap, P. L.; Albrecht, T.; Tomasek, O.
10.1101/2023.05.09.539961 — evolutionary biology — Posted on 2023-05-10
3084 Extracellular glutamate and GABA transients at the transition from interictal spiking to seizures
Shimoda, Y.; Leite, M.; Graham, R. T.; Marvin, J. S.; Hasseman, J. P.; Kolb, I.; Looger, L. L.; Magloire, V.; Kullmann, D. M.
10.1101/2020.11.13.381707 — neuroscience — Posted on 2023-05-10
3085 Fiberoptic Probe For Hemodynamic Spectroscopy in Freely Moving Mice Shows Cerebrovascular Dysregulation In Alzheimers and Glioma Models
Gareau, D. S.; Snuderl, M.; Thomas, C.; Bayin, N. S.; Placantonakis, D.; Zou, J.; Yaroslavsky, A.; Dietz, M. P.; Jacques, S. L.; Strickland, S.; Krueger, J. G.; Ahn, H. J.
10.1101/2021.05.17.444224 — neuroscience — Posted on 2023-05-10
3086 EphrinB2 knockdown in spinal cord astrocytes preserves diaphragm innervation in a mutant SOD1 mouse model of ALS
Urban, M. W.; Charsar, B. A.; Heinsinger, N. M.; Markandaiah, S. S.; Sprimont, L.; Zhou, W.; Henderson, N. T.; Ghosh, B.; Cain, R. E.; Trotti, D.; Pasinelli, P.; Wright, M. C.; Dalva, M. B.; Lepore, A. C.
10.1101/2023.05.10.538887 — neuroscience — Posted on 2023-05-10
3088 Foxj1 controls olfactory ciliogenesis and differentiation program of the olfactory sensory neurons
Rayamajhi, D.; Ege, M.; Ukhanov, K.; Ringers, C.; Zhang, Y.; Jeong, I.; D'Gama, P. P.; Li, S. S.; Cosacak, M. I.; Kizil, C.; Park, H.-C.; Yaksi, E.; Martens, J. R.; Brody, S. L.; Jurisch-Yaksi, N.; Roy, S.
10.1101/2023.05.10.540158 — neuroscience — Posted on 2023-05-10
3091 B-Cell Precursor Acute Lymphoblastic Leukemia elicits an Interferon-α/β response in Bone Marrow-derived Mesenchymal Stroma.
Smeets, M. W. E.; Steeghs, E. M. P.; Orsel, J.; Stalpers, F.; Vermeeren, M. M. P.; Veltman, C. H. J.; Nierkens, S.; van de Ven, C.; den Boer, M. L.
10.1101/2023.05.09.539232 — cancer biology — Posted on 2023-05-10
3093 De novo amyloid peptides with subtle sequence variations differ in their self-assembly and nanomechanical properties
Abernathy, H. G.; Saha, J.; Kemp, L. K.; Wadhwani, P.; Clemons, T. D.; Morgan, S. E.; Rangachari, V.
10.1101/2023.05.08.539858 — biophysics — Posted on 2023-05-10
3094 A deep catalog of protein-coding variation in 985,830 individuals
Sun, K. Y.; Bai, X.; Chen, S.; Bao, S.; Kapoor, M.; Backman, J.; Joseph, T.; Maxwell, E.; Mitra, G.; Gorovits, A.; Mansfield, A.; Boutkov, B.; Gokhale, S.; Habegger, L.; Marcketta, A.; Locke, A.; Kessler, M.; Sharma, D.; Staples, J.; Bovjin, J.; Gelfman, S.; Gioia, A. D.; Rajagopal, V.; Lopez, A.; Varela, J. R.; Alegre-Diaz, J.; Berumen, J.; Tapia-Conyer, R.; Kuri-Morales, P.; Torres, J.; Emberson, J.; Collins, R.; Regeneron Genetics Center, ; RGC-ME Cohort Partners, ; Cantor, M.; Thornton, T.; Kang, H. M.; Overton, J.; Shuldiner, A.; Cremona, M. L.; Nafde, M.; Baras, A.; Abecasis, G.; March
10.1101/2023.05.09.539329 — genetics — Posted on 2023-05-10
3096 Hot-wiring dynein-2 uncovers roles for IFT-A in retrograde train assembly and motility
Goncalves-Santos, F.; De-Castro, A. R. G.; Rodrigues, D. R. M.; De-Castro, M. J. G.; Gassmann, R.; Abreu, C. M. C.; Dantas, T. J.
10.1101/2023.05.10.539247 — cell biology — Posted on 2023-05-10
3097 HEATR5B associates with dynein-dynactin and selectively promotes motility of AP1-bound endosomal membranes
Madan, V.; Albacete Albacete, L.; Jin, L.; Scaturro, P.; Watson, J. L.; Muschalik, N.; Begum, F.; Boulanger, J.; Bauer, K.; Kiebler, M. A.; Derivery, E.; Bullock, S. L.
10.1101/2023.03.14.532574 — cell biology — Posted on 2023-05-10
3098 Confidence-based Prediction of Antibiotic Resistance at the Patient-level Using Transformers
Inda-Diaz, J. S.; Johnning, A.; Hessel, M.; Sjoberg, A.; Lokrantz, A.; Helldal, L.; Jirstrand, M.; Svensson, L.; Kristiansson, E.
10.1101/2023.05.09.539832 — microbiology — Posted on 2023-05-10
3099 Dynamics of macrophage polarization support Salmonella persistence in a whole living organism
Leiba, J.; Sipka, T.; Begon-Pescia, C.; Bernardello, M.; Tairi, S.; Bossi, L.; Gonzalez, A.-A.; Mialhe, X.; Gualda, E.; Loza-Alvarez, P.; Blanc-Potard, A.; Lutfalla, G.; Nguyen-Chi, M.
10.1101/2023.05.09.539693 — immunology — Posted on 2023-05-10
3100 Hippocampal place cell remapping occurs with memory storage of aversive experiences
Blair, G. J.; Guo, C.; Wang, S.; Fanselow, M.; Golshani, P.; Aharoni, D.; Blair, H. T.
10.1101/2022.05.26.493592 — neuroscience — Posted on 2023-05-10
3101 Radiotherapy induces persistent innate immune reprogramming of microglia into a primed state
Voshart, D. C.; Oshima, T.; Jiang, Y.; van der Linden, G. P.; Ainslie, A. P.; Reali Nazario, L.; van Buuren-Broek, F.; Scholma, A. C.; Brouwer, N.; Sewdihal, J.; Brouwer, U.; Coppes, R. P.; Holtman, I. R.; Eggen, B. J. L.; Kooistra, S. M.; Barazzuol, L.
10.1101/2023.05.10.539581 — neuroscience — Posted on 2023-05-10
3103 Joint Generation of Protein Sequence and Structure with RoseTTAFold Sequence Space Diffusion
Lisanza, S. L.; Gershon, J. M.; Tipps, S. W. K.; Arnoldt, L.; Hendel, S.; Sims, J. N.; Li, X.; Baker, D.
10.1101/2023.05.08.539766 — biochemistry — Posted on 2023-05-10
3107 Evolution of the ribbon-like organization of the Golgi apparatus in animal cells
Benvenuto, G.; Leone, S.; Astoricchio, E.; Bormke, S.; Jasek, S.; D'Aniello, E.; Kittelmann, M.; McDonald, K.; Hartenstein, V.; Baena, V.; Escriva, H.; Bertrand, S.; Schierwater, B.; Burkhardt, P.; Ruiz-Trillo, I.; Jekely, G.; Ullrich-Lüter, J.; Lüter, C.; D'Aniello, S.; Arnone, M. I.; Ferraro, F.
10.1101/2023.02.16.528797 — cell biology — Posted on 2023-05-10
3109 Neural and behavioral correlates of edible cannabis-induced poisoning: characterizing a novel preclinical model
Amissah, R. Q.; Kayir, H.; Talhat, M. A.; Hassan, A.; Gu, Y.; Johnson, R.; Urban, K.; Khokhar, J. Y.
10.1101/2023.03.15.532815 — neuroscience — Posted on 2023-05-10
3110 ECLiPSE: A Versatile Classification Technique for Structural and Morphological Analysis of Super-Resolution Microscopy Data
Hugelier, S.; Kim, H.; Gyparaki, M. T.; Bond, C.; Tang, Q.; Santiago-Ruiz, A. N.; Porta, S.; Lakadamyali, M.
10.1101/2023.05.10.540077 — biophysics — Posted on 2023-05-10
3114 Curbing zoonotic disease spread in multi-host-species systems will require integrating novel data streams and analytical approaches: evidence from a scoping review of bovine tuberculosis
Conteddu, K.; English, H. M.; Byrne, A. W.; Amin, B.; Griffin, L. L.; Kaur, P.; Morera-Pujol, V.; Murphy, K. J.; Salter-Townshend, M.; Smith, A. F.; Ciuti, S.
10.1101/2023.05.08.539893 — ecology — Posted on 2023-05-10
3115 Glucocorticoids negatively relate to body mass on the short-term in a free-ranging ungulate
Lalande, L. D.; Gilot-Fromont, E.; Carbillet, J.; Debias, F.; Duhayer, J.; Gaillard, J.-M.; Lemaitre, J.-F.; Palme, R.; Pardonnet, S.; Pellerin, M.; Rey, B.; Vuarin, P.
10.1101/2022.09.15.508076 — ecology — Posted on 2023-05-10
3117 Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation
Pikkupeura, L.; Bressan, R.; Guiu, J.; Chen, Y.; Maimets, M.; Mayer, D.; Schweiger, P.; Hansen, S.; Maciag, G.; Larsen, H.; Lohmussaar, K.; Pedersen, M.; Teves, J.; Lange, J.; Benes, V.; Sandelin, A.; Jensen, K.
10.1101/2023.05.10.540120 — developmental biology — Posted on 2023-05-10
3118 The E3 Ubiquitin Ligase Nedd4L Acts as a Checkpoint Against Activation in Quiescent Muscle Stem Cells
Blackburn, D.; Sahinyan, K.; Hernnandez Corchado, A.; Lazure, F.; Richard, V.; Raco, L.; Zahedi, R.; Borchers, C.; Lepper, C.; Kawabe, H.; Jahani-asl, A.; Najafabadi, H. S.; Soleimani, V. D.
10.1101/2023.05.10.540205 — cell biology — Posted on 2023-05-10
3119 RecA levels modulate biofilm development in Acinetobacter baumannii
Ching, C.; Brychcy, M.; Nguyen, B.; Muller, P.; Reverdy, A.; Downs, M.; Regan, S.; Isley, B.; Fowle, W.; Chai, Y.; Godoy, V. G.
10.1101/809392 — microbiology — Posted on 2023-05-10
3120 Peptidoglycan from Bacillus anthracis Inhibits Human Macrophage Efferocytosis in Part by Reducing Cell Surface Expression of MERTK and TIM-3
Mytych, J. S.; Pan, Z.; Lopez-Davis, C.; Redinger, N.; Lawrence, C.; Ziegler, J.; Popescu, N.; James, J. A.; Farris, A. D.
10.1101/2023.03.30.535001 — immunology — Posted on 2023-05-10
3121 Neurotransmitter Classification from Electron Microscopy Images at Synaptic Sites in Drosophila Melanogaster
Eckstein, N.; Bates, A. S.; Champion, A.; Du, M.; Yin, Y.; Schlegel, P.; Lu, A. K.-Y.; Rymer, T.; Finley-May, S.; Paterson, T.; Parekh, R.; Dorkenwald, S.; Matsliah, A.; Yu, S.-C.; McKellar, C.; Sterling, A.; Eichler, K.; Costa, M.; Seung, S.; Murthy, M.; Hartenstein, V.; Jefferis, G. S. X. E.; Funke, J.
10.1101/2020.06.12.148775 — neuroscience — Posted on 2023-05-10
3122 Deficits in neural encoding of speech in preterm infants
Novitskiy, N.; Chan, P. H. Y.; Chan, M.; Lai, C. M.; Leung, T. Y.; Leung, T. F.; Bornstein, M. H.; Lam, H. S.; Wong, P. C. M.
10.1101/2023.05.09.539966 — neuroscience — Posted on 2023-05-10
3123 Medication-Invariant Resting Aperiodic and Periodic Neural Activity in Parkinson's Disease
McKeown, D. J.; Jones, M.; Pihl, C.; Finley, A.; Kelley, N.; Baumann, O.; Schinazi, V.; Moustafa, A. A.; Cavanagh, J. F.; Angus, D. J.
10.1101/2023.05.08.539920 — neuroscience — Posted on 2023-05-10
3124 The spatiotemporal richness of hummingbird wing deformations
Skandalis, D. A.; Baliga, V. B.; Goller, B.; Altshuler, D. L.
10.1101/2023.05.08.539717 — zoology — Posted on 2023-05-10
3125 Phenology and social status of the endemic Sable Island Sweat Bee, Lasioglossum sablense
Richards, M. H.; Lucas, Z.; Proulx, A. N.; Corbin, L. A.-J.; Jacks, F.; Kehler, D.
10.1101/2023.05.08.539913 — zoology — Posted on 2023-05-10
3127 Hybrid vesicle and reaction-diffusion modeling with STEPS
Hepburn, I.; Lallouette, J.; Chen, W.; Gallimore, A. R.; Nagasawa, S. Y.; De Schutter, E.
10.1101/2023.05.08.539782 — systems biology — Posted on 2023-05-10
3129 "When I talk about it, my eyes light up!" Impacts of a national laboratory internship on community college student success
Cote, L. E.; Van Doren, S.; Zamora, A. N.; Jaramillo Salcido, J.; Law, E. W.; Otero Munoz, G.; Manocha, A.; Flood, C. L.; Baranger, A. M.
10.1101/2023.05.08.539924 — scientific communication and education — Posted on 2023-05-10
3131 Liraglutide protects against diastolic dysfunction and improves ventricular protein translation
Rutledge, C.; Enriquez, A.; Redding, K.; Lopez, M.; Mullett, S.; Wendell, S.; Jurczak, M.; Goetzman, E.; Kaufman, B.
10.1101/2022.08.23.504997 — physiology — Posted on 2023-05-10
3132 Conformational dynamics and DNA recognition by human MutSbeta
Lee, J.-H.; Thomsen, M.; Daub, H.; Steinbacher, S. C.; Sztyler, A.; Thieulin-Pardo, G.; Neudegger, T.; Plotnikov, N. V.; Iyer, R. R.; Wilkinson, H. A.; Monteagudo, E.; Felsenfeld, D. P.; Haque, T. S.; Finley, M.; Dominguez, C.; Vogt, T. F.; Prasad, B. C.
10.1101/2023.05.08.539930 — biophysics — Posted on 2023-05-10
3135 Characterizing fibrinolysis under flow conditions: a simplified mesoscale 3D model
Petkantchin, R.; Rousseau, A.; Eker, O.; Boudjeltia, K. Z.; Raynaud, F.; Chopard, B.
10.1101/2023.05.09.539942 — biophysics — Posted on 2023-05-10
3136 aaHash: recursive amino acid sequence hashing
Wong, J.; Kazemi, P.; Coombe, L.; Warren, R. L.; Birol, I.
10.1101/2023.05.08.539909 — bioinformatics — Posted on 2023-05-10
3138 mitoSplitter: A mitochondrial variants-based method for efficient demultiplexing of pooled single-cell RNA-seq
Lin, X.; Chen, Y.; Lin, L.; Yin, K.; Cheng, R.; Wang, X.; Guo, Y.; Wu, Z.; Zhang, Y.; Li, J.; Yang, C.; Song, J.
10.1101/2023.04.16.537058 — bioinformatics — Posted on 2023-05-10
3139 Multiple behavioral mechanisms shape development in a highly social cichlid fish
Harmon, I. P.; McCabe, E. A.; Vergun, M. R.; Weinstein, J.; Graves, H. L.; Boldt, C. M.; Bradley, D.; Lee, J.; Maurice, J. M.; Solomon-Lane, T. K.
10.1101/2023.04.14.536957 — animal behavior and cognition — Posted on 2023-05-10
3142 Anatomical and behavioral correlates of auditory perception in developmental dyslexia
Qi, T.; Mandelli, M. L.; Watson Pereira, C. L.; Wellman, E.; Bogley, R.; Licata, A. E.; Chang, E. F.; Oganian, Y.; Gorno-Tempini, M. L.
10.1101/2023.05.09.539936 — neuroscience — Posted on 2023-05-10
3143 Reward contingency gates selective cholinergic suppression of amygdala neurons
Kimchi, E. Y.; Burgos-Robles, A.; Matthews, G. A.; Chakoma, T.; Patarino, M.; Weddington, J. C.; Siciliano, C. A.; Yang, W.; Foutch, S.; Simons, R.; Fong, M.-f.; jing, m.; Li, Y.; Polley, D. B.; Tye, K. M.
10.1101/2022.02.04.479188 — neuroscience — Posted on 2023-05-10
3145 Gene networks reveal stem-cell state convergence during preneoplasia and progression to malignancy in multistage skin carcinogenesis
Taylor, M. A.; Kandyba, E.; Halliwell, K.; Del Rosario, R.; Khoroshkin, M. S.; Goodarzi, H.; Quigley, D.; Li, Y. R.; Wu, D.; Bollam, S.; Mirzoeva, O.; Akhurst, R.; Balmain, A.
10.1101/2023.05.08.539863 — cancer biology — Posted on 2023-05-10
3146 Ivermectin resistance in dung beetles exposed for multiple generations
Tokman, D. G.; Torres, A. A.; Baena-Diaz, F.; Bustos, C.; Martinez M, I.
10.1101/2023.05.08.539900 — ecology — Posted on 2023-05-10
3147 The action of physiological and synthetic steroids on the calcium channel CatSper in human sperm
Wehrli, L.; Galdadas, I.; Voirol, L.; Smiesko, M.; Cambet, Y.; Jaquet, V.; Guerrier, S.; Gervasio, F.; Nef, S.; Rahban, R.
10.1101/2023.05.10.540165 — cell biology — Posted on 2023-05-10
3149 Detection of a geminate photoproduct of bovine cytochrome c oxidase by time-resolved serial femtosecond crystallography
Yeh, S.-R.; Ishigami, I.; Rousseau, D. L.; Carbajo, S.; Zatsepin, N.; Coe, J.; Hikita, M.; Seaberg, M. H.; Sierra, R. G.; Hunter, M. S.; Fromme, P.; Fromme, R.; Nelson, G.; Grant, T.; Basu, S.; Conrad, C.
10.1101/2023.05.08.539888 — biophysics — Posted on 2023-05-10
3152 Histone H3.3 lysine 9 and 27 control repressive chromatin states at cryptic cis-regulatory elements and bivalent promoters in mouse embryonic stem cells
Trovato, M.; Bunina, D.; Yildiz, U.; Marx, N. F.-N.; Uckelmann, M.; Levina, V.; Kori, Y.; Janeva, A.; Garcia, B.; Davidovich, C.; Zaugg, J. B.; Noh, K.-M.
10.1101/2023.05.08.539859 — genomics — Posted on 2023-05-10
3153 Curbing zoonotic disease spread in multi-host-species systems will require integrating novel data streams and analytical approaches: evidence from a scoping review of bovine tuberculosis
Conteddu, K.; English, H. M.; Byrne, A. W.; Amin, B.; Griffin, L. L.; Kaur, P.; Morera-Pujol, V.; Murphy, K. J.; Salter-Townshend, M.; Smith, A. F.; Ciuti, S.
10.1101/2023.05.08.539893 — ecology — Posted on 2023-05-10
3155 Life cycle-coupled evolution of mitosis in close relatives of animals
Shah, H.; Olivetta, M.; Bhickta, C.; Ronchi, P.; Trupinic, M.; Tromer, E. C.; Tolic, I. M.; Schwab, Y.; Dudin, O.; Dey, G.
10.1101/2023.05.10.540163 — cell biology — Posted on 2023-05-10
3156 Distinct spatial patterns of neural and physiology-related activity in the human periaqueductal grey during anticipatory social stress.
Theriault, J. E.; Fischbach, A. K.; Kragel, P. A.; Wager, T. D.; Wald, L. L.; Bianciardi, M.; Choi, J.-K.; Zhang, J.; Quigley, K. S.; Barrett, L. F.; Satpute, A. B.
10.1101/2022.12.29.522243 — neuroscience — Posted on 2023-05-10
3161 Adrenergic signaling stimulates body-wide stem cell activation for limb regeneration
Payzin-Dogru, D.; Wilson, S. E.; Blair, S. J.; Savage, A. M.; Kriukov, E.; Cat, V.; Cammarata, L. V.; Erdogan, B.; Hossain, S.; Lopez, N.; Losner, J.; Velazquez Matos, J. C.; Min, S.; Dooling, K.; Groves, B.; Wong, A. Y.; Baranov, P.; Singer, H.; Chiu, I. M.; Haas, B. J.; Whited, J. L.
10.1101/2021.12.29.474455 — developmental biology — Posted on 2023-05-10
3162 Single-cell transcriptomics reveal distinctive patterns of fibroblast activation in murine heart failure with preserved ejection fraction
Lanzer, J. D.; Wienecke, L. M.; Ramirez-Flores, R. O.; Zylla, M. M.; Hartmann, N.; Sicklinger, F.; Schultz, J. H.; Frey, N.; Saez-Rodriguez, J.; Leuschner, F.
10.1101/2023.05.09.539983 — cell biology — Posted on 2023-05-10
3164 Quantitative Comparison of Presenilin Protein Expression Reveals Greater Activity of PS2-gamma-Secretase.
Eccles, M. K.; Main, N.; Sabale, M.; Roberts-Mok, B.; Agostino, M.; Groth, D.; Fraser, P. E.; Verdile, G.
10.1101/2023.05.09.540102 — cell biology — Posted on 2023-05-10
3165 TGFβ controls alveolar type 1 epithelial cell plasticity and alveolar matrisome gene transcription
Callaway, D. A.; Penkala, I. J.; Zhou, S.; Cardenas-Diaz, F.; Babu, A.; Morley, M. P.; Lopes, M.; Garcia, B.; Morrisey, E.
10.1101/2023.05.09.540035 — cell biology — Posted on 2023-05-10
3166 Melanocytes Exhibit Distinct Cell States Governed by A Gene Regulatory Network Under Stochastic Influence
AGGARWAL, A.; Nasreen, A.; Sahoo, S.; Faruq, M.; Pandey, R.; Jolly, M. K.; Singh, A.; Gokhale, R. S.; Natarajan, V. T.
10.1101/2023.05.10.540111 — cell biology — Posted on 2023-05-10
3167 New parameters for the in vitro development of cell lines from fish species
Furo, I. d. O.; Nogueira, L. S.; de Sousa, R. P. C.; Oliveira, G. C. S.; da Silva, D. M. d. S.; Malaquias, A. C.; de Oliveira, E. H. C.
10.1101/2023.05.09.539854 — cell biology — Posted on 2023-05-10
3168 Metabolic flux regulates growth transitions and antibiotic tolerance in uropathogenic Escherichia coli
Morrison, J. J.; Banas, D. A.; Madden, E. K.; DiBiasio, E. C.; Rowley, D. C.; Cohen, P. S.; Camberg, J. L.
10.1101/2023.05.09.540013 — cell biology — Posted on 2023-05-10
3169 MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisation
Pantier, R.; Brown, M.; Han, S.; Paton, K.; Meek, S.; Montavon, T.; McHugh, T.; Kelly, D. A.; Hochepied, T.; Libert, C.; Jenuwein, T.; Burdon, T.; Bird, A.
10.1101/2023.05.09.539985 — cell biology — Posted on 2023-05-10
3171 SARS-CoV-2 spike-induced syncytia are senescent and contribute to exacerbated heart failure
Wan, L.; Li, H.; Liu, M.; Ma, E.; Huang, L.; Yang, Y.; Li, Q.; Fang, Y.; Li, J.; Han, B.; Zhang, C.; Sun, L.; Hou, X.; Li, H.; Sun, M.; Qian, S.; Duan, X.; Zhao, R.; Yang, X.; Chen, Y.; Wu, S.; Zhang, X.; Zhang, Y.; Cheng, G.; Chen, G.; Gao, Q.; Xu, J.; Hou, L.; Wei, C.; Zhong, H.
10.1101/2022.10.10.511541 — cell biology — Posted on 2023-05-10
3172 iFlpMosaics: A method for the ratiometric induction and high-throughput comparative analysis of mutant and wildtype cells
Garcia-Gonzalez, I.; Gambera, S.; Regano, A.; Rocha, S. F.; Garcia-Ortega, L.; Lytvyn, M.; Sanchez-Munoz, M. S.; Garcia-Cabero, A.; Zagorac, I.; Luo, W.; Fernandez-Chacon, M.; Casquero-Garcia, V.; Lunella, F. F.; Benedito, R.
10.1101/2023.05.09.540000 — cell biology — Posted on 2023-05-10
3173 Leveraging RAS-mSIN1 Interaction to Selectively Inhibit mTORC2 Employing Competitive RAS Binding Peptide: Implications in Breast Cancer Metastasis
Miyan, J.; Kumar, N.; Malik, S. A.; Moinuddin, ; Akif, U. M.; Kumar, J.; Hameed, R.; Dubey, P.; Singh, M.; Vishwakarma, J.; Tripathi, S.; Ramachandran, R.; Siddiqi, M. I.; Kumar, V.; Bhatt, M. L. B.; Nazir, A.; Arora, A.; Bhadauria, S.
10.1101/2023.05.06.539669 — cancer biology — Posted on 2023-05-10
3177 Structural connectome architecture shapes the maturation of cortical morphology from childhood to adolescence
Liang, X.; Sun, L.; Liao, X.; Lei, T.; Xia, M.; Duan, D.; Zeng, Z.; Li, Q.; Xu, Z.; Men, W.; Wang, Y.; Tan, S.; Gao, J.-H.; Qin, S.; Tao, S.; Dong, Q.; Zhao, T.; He, Y.
10.1101/2022.12.15.520527 — neuroscience — Posted on 2023-05-10
3182 A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication and pathogenesis in vivo
Taha, T. Y.; Suryawanshi, R. K.; Chen, I. P.; Correy, G. J.; O'Leary, P. C.; Jogalekar, M. P.; McCavitt-Malvido, M.; Diolaiti, M.; Kimmerly, G. R.; Tsou, C.-L.; Martinez-Sobrido, L.; Krogan, N. J.; Ashworth, A.; Fraser, J. S.; Ott, M.
10.1101/2023.04.18.537104 — microbiology — Posted on 2023-05-10
3183 Discovery of pan-ErbB inhibitors protecting from SARS-CoV-2 replication, inflammation, and lung injury by a drug repurposing screen
Saul, S.; Karim, M.; Huang, P.-T.; Ghita, L.; Chiu, W.; Kumar, S.; Bhalla, N.; Leyssen, P.; Cohen, C. A.; Huie, K. E.; Tindle, C.; Sibai, M.; Pinsky, B. A.; Das, S.; Ghosh, P.; Dye, J.; Solow-Cordero, D. E.; Jin, J.; Jochmans, D.; Neyts, J.; Narayanan, A.; De Jonghe, S.; Einav, S.
10.1101/2021.05.15.444128 — microbiology — Posted on 2023-05-10
3185 Type I interferon expression requires transcriptional activation of IRF7 by the RNA binding protein SRSF7
Scott, H. M.; Smith, M. H.; Coleman, A. K.; Wagner, A. R.; Watson, R. O.; Patrick, K. L.
10.1101/2023.05.09.540055 — immunology — Posted on 2023-05-09
3186 Altered calcium signaling in Bergmann glia contributes to Spinocerebellar ataxia type-1
Noriega-Prieto, J. A.; Nanclares, C.; Labrada-Moncada, F. E.; Cvetanovic, M.; Araque, A.; Kofuji, P.
10.1101/2023.05.09.539932 — neuroscience — Posted on 2023-05-09
3189 CpG island turnover events predict evolutionary changes in enhancer activity
Kocher, A. A.; Dutrow, E. V.; Uebbing, S.; Yim, K. M.; Larios, M. F. R.; Baumgartner, M.; Nottoli, T.; Noonan, J. P.
10.1101/2023.05.09.540063 — genetics — Posted on 2023-05-09
3190 Simultaneous enhancement of multiple functional properties using evolution-informed protein design
Fram, B.; Truebridge, I.; Su, Y.; Riesselman, A. J.; Ingraham, J. B.; Passera, A.; Napier, E.; Thadani, N. N.; Lim, S.; Roberts, K.; Kaur, G.; Stiffler, M.; Marks, D. S.; Bahl, C. D.; Kahn, A. R.; Sander, C.; Gauthier, N. P.
10.1101/2023.05.09.539914 — synthetic biology — Posted on 2023-05-09
3191 Host genetic background regulates the capacity for anti-tumor antibody-dependent phagocytosis
Glassbrook, J. E.; Hackett, J. B.; Muniz, M. C.; Bross, M.; Dyson, G.; Movahhedin, N.; Ullrich, A.; Gibson, H. M.
10.1101/2023.05.09.540046 — cancer biology — Posted on 2023-05-09
3192 Extreme genome scrambling in cryptic Oikopleura dioica species
Plessy, C.; Mansfield, M. J.; Bliznina, A.; Masunaga, A.; West, C.; Tan, Y.; Liu, A.; Grasic, J.; del Rio Pisula, M. S.; Sanchez-Serna, G.; Fabrega-Torrus, M.; Ferrnandez-Roldan, A.; Roncalli, V.; Navratilova, P.; Thompson, E. M.; Onuma, T.; Nishida, H.; Canestro, C.; Luscombe, N. M.
10.1101/2023.05.09.539028 — genomics — Posted on 2023-05-09
3193 Ectopically expressed Airn lncRNA deposits Polycomb with a potency that rivals Xist
Trotman, J. B.; Braceros, A. K.; Bischoff, S. R.; Murvin, M. M.; Boyson, S. P.; Cherney, R. E.; Eberhard, Q. E.; Abrash, E. W.; Calabrese, M.
10.1101/2023.05.09.539960 — molecular biology — Posted on 2023-05-09
3195 Strain and temperature dependent aggregation of Candida auris is attenuated by inhibition of surface amyloid proteins
Malavia-Jones, D.; Farrer, R. A.; Stappers, M.; Edmondson, M. B.; Borman, A. M.; Johnson, E. M.; Lipke, P. N.; Gow, N. A. R.
10.1101/2023.05.09.540062 — microbiology — Posted on 2023-05-09
3196 Metagenomic analysis of milk microbiota in the bovine subclinical mastitis
Alessandri, G.; Sangalli, E.; Facchi, M.; Fontana, F.; Mancabelli, L.; Donofrio, G.; Ventura, M.
10.1101/2023.05.09.539964 — microbiology — Posted on 2023-05-09
3199 Building synthetic chromosomes from natural DNA
Coradini, A. L. V.; Ne ville, C.; Krieger, Z.; Roemer, J.; Hull, C.; Yang, S.; Lusk, D.; Ehrenreich, I.
10.1101/2023.05.09.540074 — synthetic biology — Posted on 2023-05-09
3201 Spatiotemporal dynamics of single-stranded DNA intermediates in Escherichia coli
Cherry, M. E.; Dubiel, K.; Henry, C.; Wood, E. A.; Revitt-Mills, S. A.; Keck, J.; Cox, M. M.; van Oijen, A. M.; Ghodke, H.; Robinson, A.
10.1101/2023.05.08.539320 — biophysics — Posted on 2023-05-09
3206 Ischemia/Reperfusion Injury and Oxidative Stress Impair Cardiac Desmin Proteostasis
Li, Z.; Jun, S.; Singh, K. K.; Calhoun, P. J.; Keceli, G.; Patel, K.; Kadioglu, H.; Paolocci, N.; Agnetti, G.
10.1101/2023.05.09.540017 — biochemistry — Posted on 2023-05-09
3208 Computational Framework for Statistical Epistasis Supports XOR Penetrance Function in a Living System
Batista, S.; Madar, V.; Freda, P. J.; Bhandary, P.; Ghosh, A.; Chitre, A. S.; Palmer, A. A.; Moore, J. H.
10.1101/2023.05.09.539940 — genetics — Posted on 2023-05-09
3211 Linking bacterial tetrabromopyrrole biosynthesis to coral metamorphosis
Alker, A.; Farrell, M.; Demko, A.; Purdy, T.; Adak, S.; Moore, B.; Sneed, J.; Paul, V.; Shikuma, N. J.
10.1101/2023.05.08.539906 — microbiology — Posted on 2023-05-09
3213 A protease and a lipoprotein jointly modulate the conserved ExoR-ExoS-ChvI signaling pathway critical in Sinorhizobium meliloti for symbiosis with legume hosts
Bustamante, J. A.; Ceron, J. S.; Gao, I. T.; Ramirez, H. A.; Aviles, M. V.; Bet Adam, D.; Brice, J. R.; Cuellar, R.; Dockery, E.; Jabagat, M. K.; Karp, D. G.; Lau, J. K.-O.; Li, S.; Lopez-Magana, R.; Moore, R. R.; Morin, B. K. R.; Nzongo, J.; Rezaeihaghighi, Y.; Sapienza-Martinez, J.; Tran, T. T. K.; Huang, Z.; Duthoy, A. J.; Barnett, M. J.; Long, S.; Chen, J.
10.1101/2023.05.09.539952 — microbiology — Posted on 2023-05-09
3217 Pseudorabies virus hijacks DDX3X, initiating an addictive 'mad itch' and immune suppression, to facilitate viral spread.
Cronin, S. J. F.; Tejeda, M. A.; Song, R.; Laval, K.; Cikes, D.; Ji, M.; Brai, A.; Stadlmann, J.; Novatchikova, M.; Perlot, T.; Ali, O. H.; Botta, L.; Decker, T.; Lazovic, J.; Hagelkruys, A.; Enquist, L.; Rao, S.; Koyuncu, O. O.; Penninger, J. M.
10.1101/2023.05.09.539956 — neuroscience — Posted on 2023-05-09
3220 Temporally organized representations of reward and risk in the human brain
Man, V.; Cockburn, J.; Flouty, O.; Gander, P. E.; Sawada, M.; Kovach, C. K.; Kawasaki, H.; Oya, H.; Howard, M. A.; O'Doherty, J. P.
10.1101/2023.05.09.539916 — neuroscience — Posted on 2023-05-09
3226 Multi-omic analysis of bat versus human fibroblasts reveals altered central metabolism
Jagannathan, N. S.; Koh, J. Y. P.; Lee, Y.; Sobota, R. M.; Irving, A. T.; Wang, L.-F.; Itahana, Y.; Itahana, K.; Tucker-Kellogg, L. C.
10.1101/2023.05.08.537600 — systems biology — Posted on 2023-05-09
3227 Vitamin D constrains inflammation by modulating the expression of key genes on Chr17q12-21.1
Kılıc, A.; Halu, A.; De Marzio, M.; Maiorino, E.; Duvall, M. G.; Brüggemann, T. R.; Rojas Quintero, J. J.; Chase, R.; Mirzakhani, H.; Özge Sungur, A.; Koepke, J.; Nakano, T.; Peh, H. Y.; Krishnamoorthy, N.; Abdulnour, R.-E.; Georgopoulos, K.; Litonjua, A. A.; Demay, M. B.; Renz, H.; Levy, B. D.; Weiss, S. T.
10.1101/2022.05.22.491886 — systems biology — Posted on 2023-05-09
3228 Gibberellin and the miRNA156-targeted SlSBPs synergistically regulate tomato floral meristem activity and fruit patterning
Ferigolo, L. F.; Vicente, M. H.; Correa, J. P.; Barrera-Rojas, C. H.; Silva, E. M.; Silva, G. F.; Carvalho, A.; Peres, L. E.; Ambrosano, G. B.; Margarido, G. R.; Sablowski, R.; Nogueira, F. T.
10.1101/2023.05.08.539891 — plant biology — Posted on 2023-05-09
3232 MscS is a critical component for osmotic survival of Vibrio cholerae
Ramsey, K.; Britt, M.; Maramba, J.; Ushijima, B.; Moller, E.; Anishkin, A.; Hase, C.; Sukharev, S.
10.1101/2023.05.08.539864 — biophysics — Posted on 2023-05-09
3233 Computational design of soluble analogues of integral membrane protein structures
Goverde, C. A.; Pacesa, M.; Dornfeld, L. J.; Georgeon, S.; Rosset, S.; Dauparas, J.; Shellhaas, C.; Kozlov, S.; Baker, D.; Ovchinnikov, S.; Correia, B.
10.1101/2023.05.09.540044 — bioinformatics — Posted on 2023-05-09
3234 ENDO-LYSOSOME-TARGETED NANOPARTICLE DELIVERY OF ANTIVIRAL THERAPY FOR CORONAVIRUS INFECTIONS
Petcherski, A.; Tingley, B.; Martin, A.; Adams, S.; Brownstein, A.; Steinberg, R.; Shabane, B.; Garcia, G.; Veliova, M.; Arumugaswami, V.; Colby, A.; Shirihai, O.; Grinstaff, M.
10.1101/2023.05.08.539898 — bioengineering — Posted on 2023-05-09
3235 SeMOE allows for quantitative glycan perception and exhibits anti-cancer potentiality
Tian, X.; Zheng, L.; Wang, C.; Han, Y.; Li, Y.; Cui, T.; Liu, J.; Liu, C.; Jia, G.; Yang, L.; Zeng, C.; Ding, L.; Wang, C.; Cheng, B.; Wang, M.; Xie, R.
10.1101/2023.05.08.539922 — bioengineering — Posted on 2023-05-09
3241 A phylogeny-informed characterization of global tetrapod traits addresses data gaps and biases
Moura, M. R.; Ceron, K.; Guedes, J. J. M.; Sica, Y. V.; Hart, J.; Dorman, W.; Gonzalez del Pliego, P.; Ranipeta, A.; Catenazzi, A.; Werneck, F.; Toledo, L. F.; Upham, N. S.; Tonini, J. F. R.; Colston, T. J.; Guralnick, R. P.; Bowie, R. C. K.; Pyron, R. A.; Jetz, W.
10.1101/2023.03.04.531098 — ecology — Posted on 2023-05-09
3242 Evidence for a Male Bias in Atlantic Blue Crab Pot-Based Sampling
Brunson, J. F.; Sitta, K. A.; Kendrick, M. R.; Kingsley-Smith, P. R.
10.1101/2023.05.09.538440 — ecology — Posted on 2023-05-09
3243 Transmission mode shapes host specialization of the phyllosphere microbiome
Meyer, K. M.; Muscettola, I. E.; Vasconcelos, A. L. S.; Sherman, J. K.; Metcalf, C. J. E.; Lindow, S. E.; Koskella, B.
10.1101/2023.05.08.539874 — ecology — Posted on 2023-05-09
3246 Molecular signatures associated with successful implantation of the human blastocyst
Cook-Andersen, H.; Chousal, J. N.; Srinivasan, S.; Lee, K.; To, C.; Cho, K.; Zhang, W.; Yeo, A. L.; Garzo, V. G.; Parast, M. M.; Laurent, L. C.
10.1101/2023.05.09.539763 — developmental biology — Posted on 2023-05-09
3247 Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves
Queen, R.; Crosier, M.; Eley, L.; Kerwin, J.; Turner, J. E.; Yu, J.; Dhanaseelan, T.; Overman, L.; Soetjoadi, H.; Baldock, R.; Coxhead, J.; Boczonadi, V.; Laude, A.; Cockell, S. J.; Kane, M. A.; Lisgo, S.; Henderson, D.
10.1101/2023.05.09.539950 — developmental biology — Posted on 2023-05-09
3248 Stability of mpox (monkeypox) virus in bodily fluids and wastewater
Yinda, C. K.; Morris, D. H.; Fischer, R.; Gallogly, S.; Weishampel, Z.; Port, J. R.; Bushmaker, T.; Schulz, J. E.; Bibby, K.; van Doremalen, N.; Lloyd-Smith, J. O.; Munster, V.
10.1101/2023.05.09.540015 — microbiology — Posted on 2023-05-09
3249 Dissecting the impact of somatic hypermutation on SARS-CoV-2 neutralization and viral escape
Korenkov, M.; Zehner, M.; Cohen-Dvashi, H.; Borenstein-Katz, A.; Kottege, L.; Janicki, H.; Vanshylla, K.; Weber, T.; Gruell, H.; Koch, M.; Diskin, R.; Kreer, C.; Klein, F.
10.1101/2023.05.09.539943 — immunology — Posted on 2023-05-09
3250 Toll-like receptor 7 (TLR7)-mediated antiviral response protects mice from lethal SARS-CoV-2 infection
Ghimire, R.; Shrestha, R.; Amaradhi, R.; Patton, T.; Whitley, C.; Chanda, D.; Liu, L.; More, S.; Ganesh, T.; Channappanavar, R.
10.1101/2023.05.08.539929 — immunology — Posted on 2023-05-09
3251 Systematic characterization of a non-transgenic Amyloid-beta1-42 amyloidosis model: synaptic plasticity and memory deficits in female and male mice
Jimenez-Herrera, R.; Contreras, A.; Jeremic, D.; Iborra-Lazaro, G.; Djebari, S.; Navarro-Lopez, J. D.; Jimenez-Diaz, L. D.
10.1101/2023.05.09.539973 — neuroscience — Posted on 2023-05-09
3256 Evolving spike-protein N-glycosylation in SARS-CoV-2 variants
Baboo, S.; Diedrich, J. K.; Torres, J. L.; Copps, J.; Singh, B.; Garrett, P. T.; Ward, A. B.; Paulson, J. C.; Yates, J. R.
10.1101/2023.05.08.539897 — biochemistry — Posted on 2023-05-09
3258 Enhancing associative learning in rats with a computationally designed training protocol
Zhang, X. O.; Zhang, Y.; Cho, C. E.; Engelke, D. S.; Smolen, P.; Byrne, J. H.; Do Monte, F. H.
10.1101/2022.06.08.495364 — neuroscience — Posted on 2023-05-09
3259 Building flexible and robust analysis frameworks for molecular subtyping of cancers
Pedersen, C. B.; Campos, B.; Krishnan, N. M.; Panda, B.; Vitting-Seerup, K.; Rossing, M. C.; Bagger, F. O.; Olsen, L. R.
10.1101/2023.05.01.538907 — bioinformatics — Posted on 2023-05-09
3260 Three million images and morphological profiles of cells treated with matched chemical and genetic perturbations
Chandrasekaran, S. N.; Cimini, B. A.; Goodale, A.; Miller, L.; Kost-Alimova, M.; Jamali, N.; Doench, J. G.; Fritchman, B.; Skepner, A.; Melanson, M.; Arevalo, J.; Haghighi, M.; Caicedo, J.; Kuhn, D.; Hernandez, D.; Berstler, J.; Shafqat-Abbasi, H.; Root, D.; Swalley, S. E.; Garg, S.; Singh, S.; Carpenter, A. E.
10.1101/2022.01.05.475090 — bioinformatics — Posted on 2023-05-09
3261 A single-cell strategy for the identification of intronic variants related to mis-splicing in pancreatic cancer
Duman, E. T.; Sitte, M.; Conrads, K.; Mackay, A.; Ludewig, F.; Stroebel, P.; Ellenrieder, V.; Hessmann, E.; Papantonis, A.; Salinas, G.
10.1101/2023.05.08.539836 — genomics — Posted on 2023-05-09
3263 Integrated multimodal cell atlas of Alzheimer's disease
Gabitto, M. I.; Travaglini, K. J.; Rachleff, V. M.; Kaplan, E. S.; Long, B.; Ariza, J.; Ding, Y.; Mahoney, J. T.; Dee, N.; Goldy, J.; Melief, E. J.; Brouner, K.; Campos, J.; Campos, J.; Carr, A. J.; Casper, T.; Chakrabarty, R.; Clark, M.; Cool, J.; Dalley, R.; Darvas, M.; Dolbeare, T.; Ding, S.-L.; Egdorf, T.; Esposito, L.; Ferrer, R.; Gala, R.; Gary, A.; Gloe, J.; Guilford, N.; Guzman, J.; Hirschstein, D.; Ho, W.; Jarksy, T.; Johansen, N.; Kalmbach, B. E.; Keene, L. M.; Khawand, S.; Kilgore, M.; Kirkland, A.; Kunst, M.; Lee, B. R.; Mac Donald, C. L.; Malone, J.; Maltzer, Z.; Martin, N.; McCue
10.1101/2023.05.08.539485 — genomics — Posted on 2023-05-09
3266 Levamisole suppresses activation and proliferation of human T cells by the induction of a p53-dependent DNA damage response
Khan, G. H.; Veltkamp, F.; Scheper, M.; Hoebe, R. A.; Claessen, N.; Butter, L.; Bouts, A. H. M.; Florquin, S.; Guikema, J. E.
10.1101/2023.05.08.539819 — immunology — Posted on 2023-05-09
3267 Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling
Cadinu, P.; Sivanathan, K. N.; Misra, A.; Xu, R. J.; Mangani, D.; Yang, E.; Rone, J. M.; Tooley, K.; Kye, Y.-C.; Bod, L.; Geistlinger, L.; Lee, T.; Ono, N.; Wang, G.; Sanmarco, L.; Quintana, F. J.; Anderson, A. C.; Kuchroo, V. K.; Moffitt, J. R.; Nowarski, R.
10.1101/2023.05.08.539701 — immunology — Posted on 2023-05-09
3268 Expression analysis of Huntington disease mouse models reveals robust striatum disease signatures
Obenauer, J. C.; Chen, J.; Andreeva, V.; Aaronson, J. S.; Lee, R.; Caricasole, A.; Rosinski, J.
10.1101/2022.02.04.479180 — neuroscience — Posted on 2023-05-09
3270 HISTONE DEACETYLASE 19 REGULATES SHOOT MERISTEMLESS EXPRESSION IN THE CARPEL MARGIN MERISTEM CONTRIBUTING TO OVULE NUMBER DETERMINATION AND TRANSMITTING TRACT DIFFERENTIATION
Manrique, S.; Cavalleri, A.; Guazzotti, A.; Villarino, G. H.; Simonini, S.; Bombarely, A.; Higashiyama, T.; Grossniklaus, U.; Mizzotti, C.; Pereira, A. M.; Coimbra, S.; Onelli, E.; Masiero, S.; Franks, R. G.; Colombo, L.
10.1101/2023.05.08.537343 — plant biology — Posted on 2023-05-09
3271 Topography of mutational signatures in human cancer
Otlu-Saritas, B.; Diaz-Gay, M.; Vermes, I.; Bergstrom, E. N.; Zhivagui, M.; Barnes, M.; Alexandrov, L. B.
10.1101/2022.05.29.493921 — cancer biology — Posted on 2023-05-09
3272 De novo amyloid peptides with subtle sequence variations differ in their self-assembly and nanomechanical properties
Abernathy, H. G.; Saha, J.; Kemp, L. K.; Wadhwani, P.; Clemons, T. D.; Morgan, S. E.; Rangachari, V.
10.1101/2023.05.08.539858 — biophysics — Posted on 2023-05-09
3274 Phage display assisted discovery of a pH-dependent anti-alpha-cobratoxin antibody from a natural variable domain library
Ej Efternavn, T.; Pedersen, R. W.; Rimbault, C.; Ahmadi, S.; Ledsgaard, L.; Bohn, M.-F.; Ljungars, A.; Voldborg, B. G.; Ruso-Julve, F.; Andersen, J. T.; Laustsen, A. H.
10.1101/2023.05.08.539834 — bioengineering — Posted on 2023-05-09
3275 Evolution of High-Molecular-Mass Hyaluronic Acid is Associated with Subterranean Lifestyle
Zhao, Y.; Zheng, Z.; Zhang, Z.; Hillpot, E.; Lin, Y. S.; Zakusilo, F. T.; Lu, J. Y.; Ablaeva, J.; Miller, R. A.; Nevo, E.; Seluanov, A.; Gorbunova, V.
10.1101/2023.05.08.539764 — evolutionary biology — Posted on 2023-05-09
3276 Biochemistry-informed design selects potent siRNAs against SARS-CoV-2
Houbron, E.; Mockly, S.; Rafasse, S.; Gros, N.; Muriaux, D.; Seitz, H.
10.1101/2022.12.08.519651 — molecular biology — Posted on 2023-05-09
3277 Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia
Weinberger, T.; Messerer, D.; Joppich, M.; Fischer, M.; Garcia, C.; Kumaraswami, K.; Wimmler, V.; Ablinger, S.; Räuber, S.; Fang, J.; Liu, L.; Liu, W. H.; Winterhalter, J.; Lichti, J.; Tomas, L.; Esfandyari, D.; Percin, G.; Salamanca, S. M.; Hidalgo, A.; Waskow, C.; Engelhardt, S.; Todica, A.; Zimmer, R.; Pridans, C.; Gomez-Perdiguero, E.; Schulz, C.
10.1101/2023.05.08.539799 — immunology — Posted on 2023-05-09
3278 A novel virus-induced cyclic dinucleotide, 2'3'-c-di-GMP, mediates STING-dependent antiviral immunity in Drosophila
Cai, H.; Li, L.; Slavik, K.; Huang, J.; Yin, T.; Hedelin, L.; Xiang, Z.; Yang, Y.; Li, X.; Chen, Y.; Wei, Z.; Deng, H.; Chen, D.; Jiao, R.; Martins, N.; Meignin, C.; Kranzusch, P. J.; Imler, J.-L.
10.1101/2023.05.08.539652 — immunology — Posted on 2023-05-09
3280 Attenuation of muscle spindle firing with artificially increased series compliance during stretch of relaxed muscle
Abbott, E. M.; Stephens, J. D.; Simha, S. N.; Wood, L.; Nardelli, P.; Cope, T. C.; Ting, L. H.; Sawicki, G. S.
10.1101/2023.05.08.539853 — physiology — Posted on 2023-05-09
3281 Comprehensive characterization of the neurogenic and neuroprotective action of a novel TrkB agonist using mouse and human stem cell models of Alzheimer's Disease
Charou, D.; Rogdakis, T.; Latorrata, A.; Valcarcel, M.; Papadogiannis, V.; Athanasiou, C.; Tsengenes, A.; Papadopoulou, M. A.; Lypitkas, D.; Lavigne, M. D.; Katsila, T.; Wade, R. C.; Cader, Z. M.; Calogeropoulou, T.; Gravanis, A.; Charalampopoulos, I.
10.1101/2023.05.08.539797 — pharmacology and toxicology — Posted on 2023-05-09
3282 Pseudoirreversible inhibition elicits persistent efficacy of a sphigosine-1-phosphate receptor-1 antagonist
Maruyama, Y.; Ohsawa, Y.; Suzuki, T.; Yamauchi, Y.; Ohno, K.; Inoue, H.; Yamamoto, A.; Hayashi, M.; Okuhara, Y.; Miyauchi, M.; Miyao, T.; Ishikawa, T.; Horie, K.; Hayama, M.; Akiyama, N.; Hirokawa, T.; Akiyama, T.
10.1101/2023.05.08.539826 — pharmacology and toxicology — Posted on 2023-05-09
3285 Anatomical registration of intracranial electrodes. Robust model-based localization and deformable smooth brain-shift compensation methods
Blenkmann, A. O.; Leske, S. L.; Llorens, A.; Lin, J. J.; Chang, E.; Brunner, P.; Schalk, G.; Ivanovic, J.; Larsson, P. G.; Knight, R. T.; Endestad, T.; Solbakk, A.-K.
10.1101/2023.05.08.539503 — bioinformatics — Posted on 2023-05-09
3287 Adopting Duplex Sequencing Technology for Genetic Toxicity Testing: A Proof-of-Concept Mutagenesis Experiment with N-Ethyl-N-Nitrosourea (ENU)-Exposed Rats
Smith-Roe, S. L.; Hobbs, C. A.; Hull, V.; Auman, J. T.; Recio, L.; Streicker, M.; Rivas, M. V.; Pratt, G. A.; Lo, F. Y.; Higgins, J. E.; Schmidt, E. K.; Williams, L. N.; Nachmanson, D.; Valentine, C. C.; Salk, J. J.; Witt, K. L.
10.1101/2023.05.08.539833 — genomics — Posted on 2023-05-09
3289 Auranofin Inhibition of Thioredoxin Reductase in a Preclinical Model of Small Cell Lung Cancer
Johnson, S. S.; Liu, D.; Ewald, J. T.; Robles-Planells, C.; Bayanbold, K.; Wels, B. R.; Solst, S. R.; ODorisio, M. S.; Allen, B. G.; Menda, Y.; Spitz, D. R.; Fath, M.
10.1101/2023.05.07.539772 — cancer biology — Posted on 2023-05-09
3290 Anaplerotic nutrient stress drives synergy of angiogenesis inhibitors with therapeutics targeting tumor metabolism
Khadka, S.; Lin, Y.-H.; Ackroyd, J. J.; Chen, Y.-A.; Sheng, Y.; Qian, W.; Guo, S.; Chen, Y.; Behr, E. I.; Barekatin, Y.; Uddin, M. N.; Arthur, K.; Yan, V. C.; Chang, E.; Poral, A.; Tran, T.; Hsu, W.-H.; Chaurasiya, S.; Georgiou, D. K.; Asara, J. M.; Barthel, F. P.; Millward, S. W.; DePinho, R. A.; Muller, F. L.
10.1101/2023.05.07.539744 — cancer biology — Posted on 2023-05-09
3293 A near-complete genome sequence of einkorn wheat provides insight into the evolution of wheat A subgenomes
Wang, X.; Li, H.; Shen, T.; Wang, X.; Yi, S.; Meng, T.; Sun, J.; Wang, X.; Qu, X.; Chen, S.; Guo, L.
10.1101/2023.05.07.539731 — genomics — Posted on 2023-05-09
3294 High-resolution spatial multi-omics reveals cell-type specific nuclear compartments
Takei, Y.; Yang, Y.; White, J.; Yun, J.; Prasad, M.; Ombelets, L. J.; Schindler, S.; Cai, L.
10.1101/2023.05.07.539762 — genomics — Posted on 2023-05-09
3295 The evolution of RNA interference among Metazoa
Formaggioni, A.; Cavalli, G.; Hamada, M.; Sakamoto, T.; Plazzi, F.; Passamonti, M.
10.1101/2023.05.08.538551 — evolutionary biology — Posted on 2023-05-09
3296 Neuronal IL-17 controls C. elegans developmental diapause through CEP-1/p53
Godthi, A.; Min, S.; Srijit, D.; Cruz-Corchado, J.; Deonarine, A.; Misel-Wuchter, K.; Issuree, P. D.; Prahlad, V.
10.1101/2022.11.22.517560 — developmental biology — Posted on 2023-05-09
3297 Genomic and transcriptomic characterization of Delta SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus)
Kotwa, J. D.; Lobb, B.; Masse, A.; Gagnier, M.; Aftanas, P.; Banerjee, A.; Banete, A.; Blais-Savoie, J.; Bowman, J.; Buchanan, T.; Chee, H.-Y.; Kruczkiewicz, P.; Maguire, F.; McGeer, A. J.; Nirmalarajah, K.; Soos, C.; Yip, L.; Lindsay, L. R.; Doxey, A. C.; Lung, O.; Pickering, B.; Mubareka, S.
10.1101/2022.01.20.476458 — microbiology — Posted on 2023-05-09
3306 YAP controls cell migration and invasion through a Rho-GTPase switch
Shah, S. R.; Ren, C.; Tippens, N. D.; Park, J.; Mohyeldin, A.; Wang, S.; Vela, G.; Martinez-Gutierrez, J. C.; Margolis, S. S.; Schmidt, S.; Xia, S.; Quinones-Hinojosa, A.; Levchenko, A.
10.1101/602052 — cancer biology — Posted on 2023-05-09
3307 Signal recovery in single cell batch integration
Zhang, Z.; Mathew, D.; Lim, T.; Huang, S.; Wherry, E. J.; Minn, A. J.; Ma, Z.; Zhang, N. R.
10.1101/2023.05.05.539614 — bioinformatics — Posted on 2023-05-09
3308 Near-chromosome level genome assembly of devil firefish, Pterois miles
Kitsoulis, C. V.; Papadogiannis, V.; Kristoffersen, J. B.; Kaitetzidou, E.; Sterioti, A.; Tsigenopoulos, C. S.; Manousaki, T.
10.1101/2023.01.10.523469 — genomics — Posted on 2023-05-09
3312 Succinylation of a KEAP1 sensor lysine promotes NRF2 activation
Ibrahim, L.; Stanton, C.; Nutsch, K.; Nguyen, T.; Li-Ma, C.; Ko, Y.; Lander, G. C.; Wiseman, L.; Bollong, M. J.
10.1101/2023.05.08.539908 — cell biology — Posted on 2023-05-09
3314 A Yersinia effector activates JAK-STAT signaling in human macrophages
Berneking, L.; Bekere, I.; Schnapp, M.; Huang, J.; Ruckdeschel, K.; Aepfelbacher, M.
10.1101/2023.05.08.539843 — cell biology — Posted on 2023-05-09
3316 The Pgbd5 DNA transposase is required for mouse cerebral cortex development through DNA double-strand breaks formation
Simi, A.; Ansaloni, F.; Damiani, D.; Codino, A.; Mangoni, D.; Lau Poui Cheung, P.; Vozzi, D.; Pandolfini, L.; Sanges, R.; Gustincich, S.
10.1101/2023.05.09.539730 — neuroscience — Posted on 2023-05-09
3317 Bursting with potential: How sensorimotor beta bursts develop from infancy to adulthood
Rayson, H.; Szul, M. J.; Khoueiry, P.; Debnath, R.; Gautier-Martins, M.; Ferrari, P. F.; Fox, N.; Bonaiuto, J. J.
10.1101/2023.05.09.539976 — neuroscience — Posted on 2023-05-09
3319 NRF2 connects Src tyrosine kinase to ferroptosis resistance in glioblastoma
Barila, D.; Cirotti, C.; Taddei, I.; Contadini, C.; Pepe, G.; De Bardi, M.; Borsellino, G.; Helmer-Citterich, M.
10.1101/2023.05.08.539792 — cancer biology — Posted on 2023-05-09
3322 Sprouty4 is required for Mdm2 regulation of invasion, focal adhesion formation and metastasis in cells lacking p53.
de Queiroz, R. M.; Efe, G.; Guzman, A.; Hashimoto, N.; Kawashima, Y.; Tanaka, T.; Rutsgi, A. K.; Prives, C.
10.1101/2023.05.08.539890 — cancer biology — Posted on 2023-05-09
3323 Haploinsufficiency of ZNF251 causes DNA-PKcs-dependent resistance to PARP inhibitors in BRCA1-mutated cancer cells
Li, H.; Chatla, S.; Liu, X.; Walt, M.; Kim, D.; Lian, Z.; Morton, G.; Feng, Z.; Yang, D.; Liu, H.; Sullivan-Reed, K.; Childers, W.; Yu, X.; Madzo, J.; Chitrala, K. N.; Skorski, T.; Huang, J.
10.1101/2022.09.29.510119 — cancer biology — Posted on 2023-05-09
3325 Dynamic PRC1-CBX8 stabilizes a porous structure of chromatin condensates
Uckelmann, M.; Levina, V.; Taveneau, C.; Ng, X. H.; Pandey, V.; Zhang, Q.; Flanigan, S.; Li, M.; Das, P. P.; de Marco, A.; Davidovich, C.
10.1101/2023.05.08.539931 — biophysics — Posted on 2023-05-09
3326 Characterizing fibrinolysis under flow conditions: a simplified mesoscale 3D model
Petkantchin, R.; Rousseau, A.; Eker, O.; Boudjeltia, K. Z.; Raynaud, F.; Chopard, B.
10.1101/2023.05.09.539942 — biophysics — Posted on 2023-05-09
3328 Unravelling the relationship between isolated bone matrix vesicles and forming mineral at the nanometer scale
Eufrasio Cruz, M. A.; Rutten, L.; Martens, M.; Arntz, O.; van de Loo, F.; Macias Sanchez, E.; Akiva, A.; Ciancaglini, P.; Ramos, A. P.; Sommerdijk, N.
10.1101/2023.05.09.539570 — biophysics — Posted on 2023-05-09
3332 Interplay of macromolecular interactions during assembly of human DNA polymerase δ holoenzymes and initiation of DNA synthesis
Norris, J. L.; Rogers, L. O.; Pytko, K. G.; Dannenberg, R. L.; Perreault, S.; Kaushik, V.; Kuppa, S.; Antony, E.; Hedglin, M.
10.1101/2023.05.09.539896 — biochemistry — Posted on 2023-05-09
3333 An Atypical E3 Ligase Module in UBR4 Mediates Destabilization of N-degron Substrates
Barnsby-Greer, L.; Mabbitt, P. D.; Dery, M.-A.; Squair, D. R.; Wood, N. T.; Lange, S.; Virdee, S.
10.1101/2023.05.08.539884 — biochemistry — Posted on 2023-05-09
3338 Dual agonistic and antagonistic roles of ZC3H18 provides for co-activation of distinct nuclear RNA decay pathways
Polak, P.; Garland, W.; Schmid, M.; Salerno-Kochan, A.; Jakobsen, L.; Gockert, M.; Rathore, O.; Gerlach, P.; Silla, T.; Andersen, J. S.; Conti, E.; Jensen, T. H.
10.1101/2023.05.09.539743 — molecular biology — Posted on 2023-05-09
3340 Distinct Th17 effector cytokines differentially promote microglial and blood-brain barrier inflammatory responses during post-infectious encephalitis
Wayne, C. R.; Bremner, L. I.; Faust, T. E.; Duran-Laforet, V.; Ampatey, N.; Ho, S. J.; Feinberg, P. A.; Arvanitis, P.; Ciric, B.; Ruan, C.; Elyaman, W.; Delaney, S. L.; Vargas, W. S.; Swedo, S.; Menon, V.; Schafer, D. P.; Cutforth, T.; Agalliu, D.
10.1101/2023.03.10.532135 — neuroscience — Posted on 2023-05-09
3341 Intracellular mechanics and TBX3 expression jointly dictate the spreading mode of melanoma cells in 3D environments
Higgins, G.; Higgins, F.; Peres, J.; Lang, D. M.; Abdalrahman, T.; Zaman, M.; Prince, S.; Franz, T.
10.1101/2022.06.09.495509 — biophysics — Posted on 2023-05-09
3345 Human Arm Redundancy - A New Approach for the Inverse Kinematics Problem
Barliya, A.; Krausz, N.; Naaman, H.; Chiovetto, E.; Giese, M. A.; Flash, T.
10.1101/2023.02.20.528995 — neuroscience — Posted on 2023-05-09
3348 Slit-independent guidance of longitudinal axons by Drosophila Robo3
Carranza, A.; Howard, L. J.; Brown, H. E.; Ametepe, A. S.; Evans, T. A.
10.1101/2023.05.08.539901 — developmental biology — Posted on 2023-05-09
3352 Metabolic crosstalk between hydroxylated monoterpenes and salicylic acid in tomato defence response against Pseudomonas syringae pv tomato
Perez-Perez, J.; Minguillon, S.; Kabbas-Pinango, E.; Paya, C.; Campos, L.; Rodriguez-Concepcion, M.; Rodrigo, I.; Belles, J. M.; Lopez-Gresa, M. P.; Lison, P.
10.1101/2023.05.05.539605 — plant biology — Posted on 2023-05-09
3353 Analysis of intracellular transport dynamics using quantitative phase imaging and FRET-based calcium sensors
Highland, R. E.; Rancu, A.; Price, H.; Parker, S. M.; Reynolds, M.; Hoffman, B. D.; Wax, A.
10.1101/2023.05.05.539565 — biophysics — Posted on 2023-05-09
3354 Tunable DNMT1 degradation reveals cooperation of DNMT1 and DNMT3B in regulating DNA methylation dynamics and genome organization
Scelfo, A.; Barra, V.; Abdennur, N.; Spracklin, G.; Busato, F.; Salinas-Luypaert, C.; Bonaiti, E.; Velasco, G.; Chipont, A.; Guerin, C.; Tijhuis, A.; Spierings, D. C. J.; Francastel, C.; Fooijer, F.; Tost, J.; Mirny, L. A.; Fachinetti, D.
10.1101/2023.05.04.539406 — molecular biology — Posted on 2023-05-09
3356 Anti-tau antibodies targeting a conformation-dependent epitope selectively bind seeds
HITT, B. D.; Gupta, A.; Singh, R.; Yang, T.; Beaver, J. D.; Shang, P.; White, C. L. L.; Joachimiak, L. A.; Diamond, M. I.
10.1101/2023.05.04.539475 — neuroscience — Posted on 2023-05-09
3359 Crucial neuroprotective roles of the metabolite BH4 in dopaminergic neurons
Cronin, S. J. F.; Yu, W.; Hale, A.; Crabtree, M.; Korecka, J.; Sealey, M.; Licht-Mayer, S.; Turnes, B.; da Luz Scheffer, D.; Somlyay, M.; Cikes, D.; Nagy, V.; Wolf, A.; Reither, H.; Weidinger, A.; Chabloz, A.; Kavirayani, A.; Rao, S.; Andrews, N.; Latremoliere, A.; Costigan, M.; Kozlov, A.; Douglas, G.; Freitas, F. C.; Pifl, C.; Konrat, R.; Mahad, D. J.; Bagby, S.; Isacson, O.; Walz, R.; Hallett, P.; Latini, A.; Woolf, C. J.; Je, S.; Channon, K.; Penninger, J.; Tretiakov, E.; Onji, M.; An, M.; Fox, J.; Gomez-Diaz, C.; Harkany, T.
10.1101/2023.05.08.539795 — neuroscience — Posted on 2023-05-09
3360 Short term effect of tetrahydrocurcumin on adipose angiogenesis in very high-fat diet-induced obesity mouse model
Yoysungnoen, B.; Srisawat, U.; Piyabhan, P.; Sookprasert, N.; Duansak, N.; Mathuradavong, N.; Poomipark, N.; Munkong, N.; Changtam, C.
10.1101/2023.05.05.539564 — physiology — Posted on 2023-05-09
3361 Unveiling the role of osteosarcoma-derived secretome in premetastatic lung remodeling
Almeida, S.; Santos, L.; Ribeiro, G.; Ferreira, H.; Lima, N.; Caetano, R.; Abreu, M.; Zuzarte, M.; Ribeiro, A. S.; Paiva, A.; Martins-Marques, T.; Teixeira, P.; Almeida, R.; Casanova, J.; Girao, H.; Abrunhosa, A.; Gomes, C.
10.1101/2023.05.06.539690 — cancer biology — Posted on 2023-05-09
3363 Lack of paternal silencing and ecotype-specific expression in head and body lice hybrids.
Marshall, H.; de la Filia, A. G.; Cavalieri, R.; Mallon, E. B.; Clark, J. M.; Ross, L.
10.1101/2023.05.07.539726 — evolutionary biology — Posted on 2023-05-09
3364 The Mechanical Influence of Densification on Initial Epithelial Architecture
Cammarota, C. M.; Dawney, N. S.; Bellomio, P. M.; Jung, M.; Fletcher, A. G.; Finegan, T. M.; Bergstralh, D. T.
10.1101/2023.05.07.539758 — cell biology — Posted on 2023-05-09
3365 The cervical microbiota of Hispanics living in Puerto Rico is highly volatile and dominated by L. iners regardless of HPV status
Vargas Robles, D.; Romaguera, J.; Alvarado-Velez, I.; Tosado-Rodriguez, E.; Dominicci-Maura, A.; Sanchez, M.; Wiggin, K.; Martinez-Ferrer, M.; Gilbert, J. A.; Forney, L. J.; Godoy-Vitorino, F.
10.1101/2023.05.05.539619 — microbiology — Posted on 2023-05-09
3366 CTCF barrier breaking by ZFP661 promotes protocadherin diversity in mammalian brains
Jin, J.; Ralls, S.; Wu, E.; Wolf, G.; Sun, M.-A.; Springer, D.; Cosby, R. L.; Senft, A. D.; Macfarlan, T. S.
10.1101/2023.05.08.539838 — genomics — Posted on 2023-05-08
3367 Using CRISPR/Cas9 to identify genes required for mechanosensory neuron development and function
Johnson, C. J.; Kulkarni, A.; Buxton, W. J.; Hui, T. Y.; Kayastha, A.; Khoja, A. A.; Leandre, J.; Mehta, V.; Ostrowski, L.; Pareizs, E. G.; Scotto, R. L.; Vargas, V.; Vellingiri, R. M.; Verzino, G.; Vohra, R.; Wakade, S. C.; Winkeljohn, V. M.; Winkeljohn, V. M.; Rotterman, T. M.; Stolfi, A.
10.1101/2023.05.08.539861 — developmental biology — Posted on 2023-05-08
3370 RNase H genes cause distinct impacts on RNA:DNA hybrid formation and mutagenesis genome-wide
Schroeder, J. W.; Hurto, R. L.; Randall, J. R.; Wozniak, K. J.; Timko, T. A.; Nye, T. M.; Wang, J. D.; Freddolino, P. L.; Simmons, L. A.
10.1101/2023.05.08.539860 — genetics — Posted on 2023-05-08
3372 Dehydration stress and Mayaro virus vector competence in Aedes aegypti
Manzano-Alvarez, J.; Terradas, G.; Holmes, C. J.; Benoit, J. B.; Rasgon, J. L.
10.1101/2023.05.08.539876 — microbiology — Posted on 2023-05-08
3373 IL-10 constrains sphingolipid metabolism via fatty acid desaturation to limit inflammation
York, A. G.; Skadow, M. H.; Qu, R. G.; Oh, J.; Mowel, W. K.; Brewer, J. R.; Kaffe, E.; Williams, K. J.; Kluger, Y.; Crawford, J. M.; Smale, S. M.; Bensinger, S. J.; Flavell, R. A.
10.1101/2023.05.07.539780 — immunology — Posted on 2023-05-08
3374 SGRN: A Cas12a-driven Synthetic Gene Regulatory Network System
Kang, H.; Fitch, J. C.; Varghese, R. P.; Thorne, C. A.; Cusanovich, D. A.
10.1101/2023.05.08.539911 — synthetic biology — Posted on 2023-05-08
3377 Site-Specific Introduction of Alanines for the NMR Investigation of Low-Complexity Regions and Large Biomolecular Assemblies
Elena-Real, C. A.; Urbanek, A.; Imbert, L.; Morato, A.; Fournet, A.; Allemand, F.; Sibille, N.; BOISBOUVIER, J.; Bernado, P.
10.1101/2023.05.08.539737 — biochemistry — Posted on 2023-05-08
3386 Jumbo phages are active against extensively-drug-resistant eyedrop-associated Pseudomonas aeruginosa infections.
Cobian-Guemes, A. G.; Ghatbale, P.; Blanc, A. N.; Morgan, C. J.; Garcia, A.; Leonard, J.; Huang, L.; Kovalick, G.; Proost, M.; Chiu, M.; Kuo, P.; Oh, J.; Karthikeyan, S.; Knight, R.; Pogliano, J.; Schooley, R.; Pride, D.
10.1101/2023.05.08.539869 — microbiology — Posted on 2023-05-08
3387 Mutualism reduces the severity of gene disruptions in predictable ways across microbial communities.
Martinson, J. N. V.; Chacon, J. M.; Smith, B. A.; Villarreal, A. R.; Hunter, R. C.; Harcombe, W. R.
10.1101/2023.05.08.539835 — microbiology — Posted on 2023-05-08
3388 Cell behaviors underlying Myxococcus xanthus aggregate coarsening
Murphy, P.; Comstock, J.; Khan, T.; Zhang, J.; Welch, R. D.; Igoshin, O. A.
10.1101/2023.05.08.539855 — microbiology — Posted on 2023-05-08
3389 Dimeric Transmembrane Structure of the SARS-CoV-2 E Protein
Zhang, R.; Qin, H.; Prasad, R.; Fu, R.; Zhou, H.-X.; Cross, T. A.
10.1101/2023.05.07.539752 — biophysics — Posted on 2023-05-08
3390 Robust identification of perturbed cell types in single-cell RNA-seq data
Nicol, P. B.; Paulson, D.; Qian, G.; Liu, X. S.; Irizarry, R. A.; Sahu, A. D.
10.1101/2023.05.06.539326 — bioinformatics — Posted on 2023-05-08
3391 A multiadjuvant polysaccharide-amino acid-lipid (PAL) subunit nanovaccine generates robust systemic and lung-specific mucosal immune responses against SARS-CoV-2 in mice
Pandey, B.; Wang, Z.; Jimenez, A.; Bhatia, E.; Jain, R.; Beach, A.; Maniar, D.; Hosten, J.; O'Farrell, L.; Vantucci, C.; Hur, D.; Noel, R. K.; Ringquist, R. M.; Smith, C.; Ochoa, M. A.; Roy, K.
10.1101/2023.05.05.539395 — bioengineering — Posted on 2023-05-08
3393 CD38 regulates ovarian function and fecundity via NAD+ metabolism
Perrone, R.; Ashok Kumaar, P. V.; Haky, L.; Hahn, C.; Riley, R.; Balough, J.; Zaza, G.; Soygur Kaya, B.; Hung, K.; Prado, L.; Kasler, H. G.; Tiwari, R.; Matsui, H.; Vega Hormazabal, G.; Duncan, F. E.; Verdin, E.
10.1101/2023.05.08.539779 — developmental biology — Posted on 2023-05-08
3394 Host inducible-HSP70A1A is an irresistible drug target to combat SARS-CoV-2 infection and pathogenesis
Joshi, P.; Garg, S.; Mani, S.; Jakhar, K.; Marothia, M.; Shoaib, R.; Biswas, S.; Singhal, J.; Behl, A.; Kahlon, A. K.; Shevtsov, M.; Garg, P.; Singh, S.; Ranganathan, A.
10.1101/2023.05.05.539661 — microbiology — Posted on 2023-05-08
3395 Rectal and vaginal challenge with mpox virus increases virus dissemination and contact transmission compared to skin challenge in the multimammate rat (Mastomys natalensis)
Port, J. R.; Riopelle, J. C.; Smith, S. G.; Myers, L.; Lewis, M. C.; Gallogly, S.; Okumura, A.; Schukz, J. E.; Rosenke, R.; Prado-Smith, J.; Carmody, A.; Bane, S.; Smith, B. J.; Saturday, G.; Feldmann, H.; Rosenke, K.; Munster, V. J.
10.1101/2023.05.07.539622 — microbiology — Posted on 2023-05-08
3396 Connectome-wide structure-function coupling models implicate polysynaptic alterations in autism
Park, B.-y.; Benkarim, O.; Weber, C. F.; Kebets, V.; Fett, S.; Yoo, S.; Di Martino, A.; Milham, M. P.; Misic, B.; Hong, S.-J.; Bernhardt, B.
10.1101/2023.05.08.539817 — neuroscience — Posted on 2023-05-08
3397 Prefrontal cortex proteomic alteration after social instability stress in adolescents rats
Santos, E.; Terceiro, A. F.; Vitorino, R.; Lopes, I. M.; Alves, R.; Relvas, J. B.; Summavielle, T.; Magalhaes, A.
10.1101/2023.05.08.539806 — neuroscience — Posted on 2023-05-08
3399 Enhancing Collaborative Neuroimaging Research: Introducing COINSTAC Vaults for Federated Analysis and Reproducibility
Panta, S.; Martin, D.; Basodi, S.; Rootes-Murdy, K.; Prae, P.; T Baker, B.; Kelly, R.; Romero, J.; Plis, S.; Calhoun, V.; Bockholt, J.; Sarwate, A.; B Esper Franco, N.; R Franco, A.; Gazula, H.; Turner, J.
10.1101/2023.05.08.539852 — neuroscience — Posted on 2023-05-08
3404 Optogenetic determination of dynamic and cell-type-specific chloride equilibrium potentials
Burman, R. J.; Diviney, T.; Calin, A.; Gothard, G.; Jouhanneau, J.-S. M.; Poulet, J. F. A.; Sen, A.; Akerman, C. J.
10.1101/2023.05.08.539831 — neuroscience — Posted on 2023-05-08
3407 Short- and long-term high-fat diet exposure differentially alters phasic and tonic GABAergic signalling onto lateral orbitofrontal pyramidal neurons
Seabrook, L. T.; Peterson, C.; Noble, D.; Tayyab, T.; Kenney, T.; Judge, A. K.; Armstrong, M.; Lin, S.; Borgland, S. L.
10.1101/2023.05.08.539875 — neuroscience — Posted on 2023-05-08
3408 A Mechanism Underpinning the Bioenergetic Metabolism-Regulating Function of Gold Nanocatalysts
Wang, Z.; Henriques, A.; Rouviere, L.; Callizot, N.; Tan, L.; Hotchkin, M. T.; Rossignol, R.; Mortenson, M. G.; Ho, K. S.; Wang, H.
10.1101/2023.05.08.539856 — neuroscience — Posted on 2023-05-08
3409 Patterned Metal Grids for Flexible and Transparent Neural Microelectrode Arrays
Trepo, I.; Pinto, J. V.; Santa, A.; Pereira, M. E.; Calmeiro, T.; Coelho, B.; Henriques, C.; Martins, R.; Fortunato, E.; Carey, M. R.; Marques, H. G.; Barquinha, P.; Neto, J. P.
10.1101/2023.05.08.539822 — neuroscience — Posted on 2023-05-08
3410 Monomethylation of Lysine 27 at Histone 3 Confers Lifelong Susceptibility to Stress
Torres-Berrio, A.; Estill, M.; Ramakrishnan, A.; Kronman, H.; Patel, V.; Minier-Toribio, A.; Issler, O.; Browne, C. J.; Parise, E.; van der Zee, Y.; Walker, D.; Martinez-Rivera, F. J.; Lardner, C. K.; Durand, R.; Russo, S.; Shen, L.; Sidoli, S.; Nestler, E. J.
10.1101/2023.05.08.539829 — neuroscience — Posted on 2023-05-08
3411 Structural and functional damage to neuronal nuclei caused by extracellular tau oligomers
Sun, X.; Eastman, G.; Shi, Y.; Saibaba, S.; Oliveira, A. K.; Lukens, J. R.; Norambuena, A.; Mandell, J. W.; Bloom, G. S.
10.1101/2023.05.08.539873 — neuroscience — Posted on 2023-05-08
3414 Nutrient-driven dedifferentiation of enteroendocrine cells promotes adaptive intestinal growth
Nagai, H.; Nagai, L. A. E.; Tasaki, S.; Nakato, R.; Umetsu, D.; Kuranaga, E.; Miura, M.; Nakajima, Y.
10.1101/2023.05.08.539820 — developmental biology — Posted on 2023-05-08
3415 Optogenetic inhibition of Gα signalling alters and regulates circuit functionality and early circuit formation
Lockyer, J. L.; Reading, A.; Vicenzi, S.; Delandre, C.; Marshall, O. J.; Gasperini, R.; Foa, L.; Lin, J. Y.-l.
10.1101/2023.05.06.539674 — neuroscience — Posted on 2023-05-08
3416 Transplanted Autologous Neural Stem Cells Show Promise in Restoring Motor Function in Monkey Spinal Cord Injury
Jaberi, R.; Jabbari, R.; Hajinasrollah, M.; Mirsadeghi, S.; Rahmani, S.; Zarei-Khairabadi, M.; Rezaei, O.; Nabavi, S.-M.; Kiani, s.
10.1101/2023.05.06.539673 — neuroscience — Posted on 2023-05-08
3419 Exploration biases how forelimb reaches to a spatial target are learned
Mosberger, A. C.; Sibener, L. J.; Chen, T. X.; Rodrigues, H. F.; Hormigo, R.; Ingram, J. N.; Athalye, V. R.; Tabachnik, T.; Wolpert, D. M.; Murray, J. M.; Costa, R. M.
10.1101/2023.05.08.539291 — neuroscience — Posted on 2023-05-08
3420 Asymmetric control of food intake by left and right vagal sensory neurons
M de Araujo, A.; Braga, I.; Leme, G.; Singh, A.; McDougle, M.; Yang, M.; Smith, J.; Vergara, M.; Lin, M.; Khoshbouei, H.; Krasue, E.; Oliveira, A. G.; de Lartigue, G.
10.1101/2023.05.08.539627 — neuroscience — Posted on 2023-05-08
3421 The AGNOSTIC MRS Benchmark Dataset: Deep Learning for Out-of-voxel Artifacts
Gudmundson, A. T.; Davies-Jenkins, C. W.; Ozdemir, I.; Murali-Manohar, S.; Zollner, H. J.; Song, Y.; Hupfeld, K. E.; Schnitzler, A.; Oeltzschner, G.; Stark, C. E. L.; Edden, R. A. E.
10.1101/2023.05.08.539813 — neuroscience — Posted on 2023-05-08
3422 Lipidome unsaturation affects the morphology and proteome of the Drosophila eye.
Kumar, M.; Has, C.; Lam-Kamath, K.; Ayciriex, S.; Dewett, D.; Bashir, M.; Poupault, C.; Schuhmann, K.; Knittelfelder, O.; Raghuraman, B. K.; Ahrends, R.; Rister, J.; Shevchenko, A.
10.1101/2023.05.07.539765 — neuroscience — Posted on 2023-05-08
3424 NF-κB c-REL-OTUD4 axis regulates B-cell receptor in B-cell lymphoma
Katab, E.; Kumar, A. J.; Steiger, K.; Mergner, J.; Azkargorta, M.; Yeroslaviz, A.; Elortza, F.; Fernandez-Saiz, V.
10.1101/2023.05.06.539691 — cancer biology — Posted on 2023-05-08
3425 Local haplotype visualization for trait association analysis with crosshap
Marsh, J. I.; Petereit, J.; Johnston, B. A.; Bayer, P. E.; Tay Fernandez, C. G.; Al-Mamun, H. A.; Batley, J.; Edwards, D.
10.1101/2023.05.07.539781 — bioinformatics — Posted on 2023-05-08
3426 Direct measurements of collagen fiber recruitment in the posterior pole of the eye
Lee, P.-Y.; Fryc, G.; Gnalian, J.; Hua, Y.; Waxman, S.; Zhong, F.; Yang, B.; Sigal, I. A.
10.1101/2023.05.07.539784 — bioengineering — Posted on 2023-05-08
3428 Functional interrogation of twenty type 2 diabetesassociated genes using isogenic hESC-derived β-like cells
Xue, D.; Narisu, N.; Taylor, D. L.; Zhang, M.; Grenko, C.; Taylor, H. J.; Yan, T.; Tang, X.; Sinha, N.; Zhu, J.; Vandana, J. J.; Chong, A. C. N.; Lee, A.; Mansell, E. C.; Swift, A. J.; Erdos, M. R.; Zhou, T.; Bonnycastle, L. L.; Zhong, A.; Chen, S.; Collins, F. S.
10.1101/2023.05.07.539774 — genetics — Posted on 2023-05-08
3432 Probing the mechanism of Cbl-b inhibition by a small-molecule inhibitor
Kimani, S.; Perveen, S.; Szewczyk, M.; Zeng, H.; Dong, A.; Li, F.; Ghiabi, P.; Li, Y.; Chau, I.; Arrowsmith, C.; Barsyte-Lovejoy, D.; Santhakumar, V.; Vedadi, M.; Halabelian, L.
10.1101/2023.05.05.539612 — immunology — Posted on 2023-05-08
3433 Apposed networks of interacting TCRs and BCRs exhibiting mosaicked CDR3 sequences made of fixed junctional motifs
Ahmed, R.; Majety, N.; Chan, K. C.; Giwa, A.; Heinemann, J.; Zhang, H.; Margolick, J.; Al-Hallaf, R.; Paul, P.; Bell, D. R.; Song, Y.; Lee, S.; Zhou, R.; Wolfe, R. M.; Donner, T.; Jie, C.; Hamad, A. R. A.
10.1101/2023.05.06.539704 — immunology — Posted on 2023-05-08
3434 SHORT-TERM CALORIC RESTRICTION IN MICE PROMOTES RESOLUTION OF ATHEROSCLEROSIS, WHILE WEIGHT REGAIN ACCELERATES ITS PROGRESSION
Scolaro, B.; Brown, E. J.; Krautter, F.; Petitjean, M.; Donahoe, C.; Pena, S.; Garabedian, M. L.; Nikain, C. A.; Laskou, M.; Tufanli, O.; Hannemann, C.; Aouadi, M.; Weinstock, A.; Fisher, E.
10.1101/2023.05.07.539777 — immunology — Posted on 2023-05-08
3436 Towards a human brain EV atlas: Characteristics of EVs from different brain regions, including small RNA and protein profiles
Huang, Y.; Arab, T.; Russell, A. E.; Mallick, E. R.; Nagaraj, R.; Gizzie, E.; Redding, J.; Troncoso, J. C.; Pletnikova, O.; Turchinovich, A.; Routenberg, D. A.; Witwer, K. W.
10.1101/2023.05.06.539665 — neuroscience — Posted on 2023-05-08
3437 SanPy: A whole-cell electrophysiology analysis pipeline.
Guarina, L.; Le, J. T.; Griffith, T.; Santana, L. F.; Cudmore, R. H.
10.1101/2023.05.06.539660 — neuroscience — Posted on 2023-05-08
3438 eIF2B Activator Rescues Neonatal Lethality of an eIF2Bα Sugar Phosphate Binding Mutation Associated with Vanishing White Matter Disease
Lee, J. J.; Ly, N.; Kunjamma, R. B.; Robb, H. M.; Mohler, E. G.; Sridar, J.; Hao, Q.; Zavala-Solorio, J.; Zhang, C.; Kolumam, G.; Bruggen, N. v.; Connelly, C. F.; Sidrauski, C.
10.1101/2023.05.06.539602 — neuroscience — Posted on 2023-05-08
3439 Cortical cerebrovascular and metabolic perturbations in the 5xFAD mouse model of Alzheimer's disease
Jullienne, A.; Szu, J. I.; Quan, R.; Trinh, M. V.; Norouzi, T.; Noarbe, B. P.; Bedwell, A. A.; Eldridge, K.; Persohn, S. C.; Territo, P. R.; Obenaus, A.
10.1101/2023.05.05.539629 — neuroscience — Posted on 2023-05-08
3440 Insights from a survey of mentorship experiences by graduate and postdoctoral researchers
Sarabipour, S.; Niemi, N. M.; Burgess, S. J.; Smith, C. T.; Bisson Filho, A. W.; Ibrahim, A.; Clark, K.
10.1101/2023.05.05.539640 — scientific communication and education — Posted on 2023-05-08
3443 Functional effect of indole-3 carbinol in the viability and invasive properties of cultured cancer cells.
Baez-Gonzalez, A. S.; Carrazco-Carrillo, J. A.; Figueroa-Gonzalez, G.; Quintas-Gaanados, L. I.; Padilla-Benavides, T.; Reyes-Hernandez, O. D.
10.1101/2023.05.06.539692 — cancer biology — Posted on 2023-05-08
3444 EMP3 sustains oncogenic EGFR/CDK2 signaling by restricting receptor degradation in glioblastoma
Martija, A. A.; Krauss, A.; Baechle, N.; Doth, L.; Christians, A.; Krunic, D.; Schneider, M.; Helm, D.; Will, R.; Hartmann, C.; Herold-Mende, C.; von Deimling, A.; Pusch, S.
10.1101/2023.05.06.539678 — cancer biology — Posted on 2023-05-08
3445 Leveraging RAS-mSIN1 Interaction to Selectively Inhibit mTORC2 Employing Competitive RAS Binding Peptide: Implications in Breast Cancer Metastasis
Miyan, J.; Kumar, N.; Malik, S. A.; Moinuddin, ; Akif, U. M.; Kumar, J.; Hameed, R.; Dubey, P.; Singh, M.; Vishwakarma, J.; Tripathi, S.; Ramachandran, R.; Siddiqi, M. I.; Kumar, V.; Bhatt, M. L. B.; Nazir, A.; Arora, A.; Bhadauria, S.
10.1101/2023.05.06.539669 — cancer biology — Posted on 2023-05-08
3446 SpatialData: an open and universal data framework for spatial omics
Marconato, L.; Palla, G.; Yamauchi, K. A.; Virshup, I.; Heidari, E.; Treis, T.; Toth, M.; Shrestha, R.; Vöhringer, H.; Huber, W.; Gerstung, M.; Moore, J.; Theis, F. J.; Stegle, O.
10.1101/2023.05.05.539647 — bioinformatics — Posted on 2023-05-08
3448 Endogenous fine-mapping of functional regulatory elements in complex genetic loci
Zhao, K.; Zhou, Y.; Wu, C.; Wang, J.; Yao, H.; Cheng, X.; Zhao, L.; Wang, W.; Chu, X.; Yi, X.; Chen, Y.; Li, M.; Lu, W.; Chen, K.; Sham, P. C.; Li, M. J.
10.1101/2023.05.06.539696 — genomics — Posted on 2023-05-08
3451 The CD4 transmembrane GGXXG and juxtamembrane (C/F)CV+C motifs mediate pMHCII-specific signaling independently of CD4-Lck interactions
Lee, M. S.; Tuohy, P. J.; Kim, C. Y.; Yost, P. P.; Lichauco, K.; Parrish, H. L.; Van Doorslaer, K.; Kuhns, M. S.
10.1101/2023.05.05.539613 — immunology — Posted on 2023-05-08
3453 Screening effects of HCN channel blockers on sleep/wake behavior in zebrafish
Doldur Balli, F.; Keenan, B.; Zimmerman, A. J.; Veatch, O. J.; Smieszek, S. P.; Pack, A. I.
10.1101/2023.05.05.539631 — pharmacology and toxicology — Posted on 2023-05-08
3454 DNA repair and anti-cancer mechanisms in the longest-living mammal: the bowhead whale
Firsanov, D.; Zacher, M.; Tian, X.; Zhao, Y.; George, J. C.; Sformo, T. L.; Tombline, G.; Biashad, S. A.; Gilman, A.; Hamilton, N.; Patel, A.; Straight, M.; Lee, M.; Lu, J. Y.; Haseljic, E.; Williams, A.; Miller, N.; Gladyshev, V. N.; Zhang, Z.; Vijg, J.; Seluanov, A.; Gorbunova, V.
10.1101/2023.05.07.539748 — cancer biology — Posted on 2023-05-08
3456 Allosteric inhibition of the epidermal growth factor receptor through disruption of transmembrane interactions
Rybak, J. A.; Sahoo, A. R.; Kim, S.; Pyron, R. J.; Pitts, S. B.; Guleryuz, S.; Smith, A. W.; Buck, M.; Barrera, F. N.
10.1101/2022.10.31.514582 — cell biology — Posted on 2023-05-08
3457 Association between Prevalent Flagellated Bacteria in Gut Microbiota and Cardiovascular Benefits in Humans
Yiu, J. H. C.; Cai, J.; Cheung, S. W.; Chin, K. T. C.; Chan, C. F.; Ma, E. S. C.; Sharma, R.; Dorweiler, B.; Woo, C. W. H.
10.1101/2023.05.04.539500 — systems biology — Posted on 2023-05-08
3460 SKOOTS: Skeleton oriented object segmentation for mitochondria
Buswinka, C. J.; Nitta, H.; Osgood, R. T.; Indzhykulian, A. A.
10.1101/2023.05.05.539611 — neuroscience — Posted on 2023-05-08
3463 Signal recovery in single cell batch integration
Zhang, Z.; Mathew, D.; Lim, T.; Huang, S.; Wherry, E. J.; Minn, A. J.; Ma, Z.; Zhang, N. R.
10.1101/2023.05.05.539614 — bioinformatics — Posted on 2023-05-08
3465 Genome mining yields new disease-associated ROMK variants with distinct defects
Nguyen, N. H.; Sarangi, S.; McChesney, E. M.; Sheng, S.; Porter, A. W.; Kleyman, T. R.; Pitluk, Z. W.; Brodsky, J. L.
10.1101/2023.05.05.539609 — genetics — Posted on 2023-05-08
3467 TGF-β Ligand Interactions in the Response of Caenorhabditis elegans to Bacterial Pathogens
Ciccarelli, E. J.; Wing, Z.; Bendelstein, M.; Johal, R. K.; Singh, G.; Monas, A.; Savage-Dunn, C.
10.1101/2023.05.05.539606 — physiology — Posted on 2023-05-08
3469 NON-TOXIC ACID-FREE GLYOXAL FIXATIVE FOR VETERINARY HISTOPATHOLOGY, IMMUNOHISTOCHEMISTRY AND MOLECULAR ANALYSIS
Zappulli, V.; Torrigiani, F.; Moccia, V.; Detillo, P.; Gola, C.; Minoli, L.; Morello, E. M.; Ferraris, E. I.; Rigillo, A.; Caicci, F.; Dalla Rovere, G.; De Biase, D.; Riccio, L.; Rondena, M.; Iussich, S.; Bussolati, B.
10.1101/2023.05.05.539541 — pathology — Posted on 2023-05-08
3473 Skin permeable polymer for noninvasive transdermal insulin delivery
Wei, Q.; He, Z.; Xiang, J.; Piao, Y.; Huang, J.; Geng, Y.; Zhu, H.; Li, Z.; Zeng, J.; Zhang, Y.; Lu, H.; Zhou, Q.; Shao, S.; Tang, J.; Zhou, Z.; Zhou, R.; Shen, Y.
10.1101/2023.05.05.539551 — bioengineering — Posted on 2023-05-08
3474 Altered Brain Dynamics in idiopathic REM sleep behavior disorder: Implications for a continuum from prodromal to overt alpha-synucleinopathies
Roascio, M.; Wang, S. H.; Myrov, V.; Siebenhuhner, F.; Tro', R. D.; Mattioli, P.; Fama', F.; Morbelli, S. D.; Pardini, M.; Palva, J. M.; Arnaldi, D.; Arnulfo, G.
10.1101/2023.05.05.539548 — bioengineering — Posted on 2023-05-08
3476 Theranostic gold in a gold cage nanoparticle for photothermal ablation and photoacoustic imaging of skin and oral infections
Hajfathalian, M.; de Vries, C. R.; Hsu, J. C.; Amirshaghaghi, A.; Dong, Y. C.; Ren, Z.; Liu, Y.; Huang, Y.; Li, Y.; Knight, S.; Jonnalagadda, P.; Zlitni, A.; Grice, E.; Bollyky, P. L.; Koo, H.; Cormode, D. P.
10.1101/2023.05.05.539604 — bioengineering — Posted on 2023-05-08
3479 Predicting the timing of ecological phenomena across regions using citizen science data
Capinha, C.; Ceia-Hasse, A.; de-Miguel, S.; Vila-Vicosa, C.; Porto, M.; Jaric, I.; Tiago, P.; Fernandez, N.; Valdez, J.; McCallum, I.; Pereira, H. M.
10.1101/2023.05.05.539567 — ecology — Posted on 2023-05-08
3481 Intermediate Filaments Associate with Aggresome-like Structures in Proteostressed C. elegans Neurons and Influence Large Vesicle Extrusions as Exophers
Arnold, M. L.; Cooper, J. F.; Androwski, R.; Ardeshna, S.; Melentijevic, I.; Smart, A. J.; Guasp, R. J.; Nguyen, K. C.; Bai, G.; Hall, D. H.; Grant, B. D.; Driscoll, M.
10.1101/2022.08.03.501714 — cell biology — Posted on 2023-05-08
3482 Prior flavivirus immunity skews the yellow fever vaccine response to expand cross-reactive antibodies with increased risk of antibody dependent enhancement of Zika and dengue virus infection
Santos-Peral, A.; Luppa, F.; Goresch, S.; Nikolova, E.; Zaucha, M.; Lehmann, L.; Dahlstroem, F.; Karimzadeh, H.; Kummerer, B. M.; Thorn-Seshold, J.; Winheim, E.; Dobler, G.; Hoelscher, M.; Endres, S.; Krug, A. B.; Pritsch, M.; Barba-Spaeth, G.; Rothenfusser, S.
10.1101/2023.05.07.539594 — immunology — Posted on 2023-05-08
3485 HIV-1 Vpu protein forms stable oligomers in aqueous solution via its transmembrane domain self-association
Majeed, S.; Dang, L.; Islam, M. M.; Ishola, O.; Borbat, P. P.; Ludtke, S. J.; Georgieva, E. R.
10.1101/2023.05.08.539839 — biophysics — Posted on 2023-05-08
3489 Structural polymorphisms within a common powdery mildew effector scaffold as a driver of co-evolution with cereal immune receptors
Cao, Y.; Kuemmel, F.; Logemann, E.; Gebauer, J. M.; Lawson, A. W.; Yu, D.; Uthoff, M.; Keller, B.; Jirschitzka, J.; Baumann, U.; Tsuda, K.; Chai, J.; Schulze-Lefert, P.
10.1101/2023.05.05.539654 — plant biology — Posted on 2023-05-08
3490 PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 2 localizes to the Golgi
Fuchs, P.; Feixes, E.; Arruda, P.; Feitosa-Araujo, E.; Fernie, A. R.; Grefen, C.; Lichtenauer, S.; Linka, N.; de Godoy Maia, I.; Meyer, A. J.; Schilasky, S.; Sweetlove, L. J.; Wege, S.; Weber, A. P. M.; Millar, A. H.; Keech, O.; Florez-Sarasa, I.; Barreto, P.; Schwarzländer, M.
10.1101/2023.05.06.539686 — plant biology — Posted on 2023-05-08
3492 tRNASer overexpression induces adaptive mutations in NSCLC tumors
Ferreira, M.; Pinheiro, M.; Reis, A.; Andre, A.; Rocha, S.; Santos, M. A. S.; Santos, M.; Oliveira, C.
10.1101/2023.05.06.539672 — cancer biology — Posted on 2023-05-08
3493 Cellular visualization of G-quadruplex RNA via fluorescence lifetime imaging microscopy
Robinson, J.; Stenspil, S. G.; Maleckaite, K.; Di Antonio, M.; Vilar, R.; Kuimova, M.
10.1101/2023.05.07.539224 — biophysics — Posted on 2023-05-08
3494 Direct prediction of intrinsically disordered protein conformational properties from sequence
Lotthammer, J. M.; Ginell, G. M.; Griffith, D.; Emenecker, R. J.; Holehouse, A. S.
10.1101/2023.05.08.539824 — biophysics — Posted on 2023-05-08
3497 Deep ultraviolet-excited fluorescence histology with fibre optic illumination for tissue microtopography and quantitative mapping
Yong, A. S. K.; Tan, K. H.; Ang, J. L. Y.; Tan, C. W. X.; Kng, J. S. J.; Tan, C. J. J.; Soh, R. H. K.; Liang, K.
10.1101/2022.12.28.521919 — bioengineering — Posted on 2023-05-08
3498 From breast cancer cell homing to the onset of early bone metastasis: dynamic bone (re)modeling as a driver of metastasis
Young, S. A. E.; Heller, A.-D.; Garske, D. S.; Rummler, M.; Qian, V.; Ellinghaus, A.; Duda, G. N.; Willie, B.; Grueneboom, A.; Cipitria, A.
10.1101/2023.01.24.525352 — bioengineering — Posted on 2023-05-08
3500 Bacterial Cytochrome P450-catalyzed Post-translational Macrocyclization
He, B.-B.; Cheng, Z.; Liu, J.; Zhong, Z.; Gao, Y.; Liu, H.; Li, Y.-X.
10.1101/2023.05.08.539676 — biochemistry — Posted on 2023-05-08
3502 Isoform-specific translational control is evolutionarily conserved in primates
Draper, J. M.; Philipp, J.; Neeb, Z. T.; Thomas, R.; Katzman, S.; Salama, S.; Haussler, D.; Sanford, J.
10.1101/2023.04.21.537863 — molecular biology — Posted on 2023-05-08
3503 Alpha-1-antitrypsin and its variant-dependent role in COVID-19 pathogenesis
Stevens, C. S.; Oguntuyo, K. Y.; Kowdle, S.; Gowlikar, A.; Siddiquey, M. N.; Acklin, J. A.; Haas, G.; Schilke, R. M.; Woolard, M. D.; Zhang, H.; Brambilla, L.; Ikegame, S.; Hung, C.-t.; Lim, J. K.; Cross, R. W.; Geisbert, T. W.; Ivanov, S. S.; Kamil, J. P.; Lee, B.
10.1101/2020.08.14.248880 — microbiology — Posted on 2023-05-08
3504 Linking hubness, embryonic neurogenesis, transcriptomics and diseases in human brain networks
Diez, I.; Moreno, F. G.; Sainz, N. C.; Stramaglia, S.; Reyes, A. N.; D'Amato, M.; Cortes, J. M.; Bonifazi, P.
10.1101/2022.04.01.486541 — neuroscience — Posted on 2023-05-08
3509 Biosynthesis of gibberellin-related compounds modulates far-red light responses in the liverwort Marchantia polymorpha
Sun, R.; Okabe, M.; Miyazaki, S.; Ishida, T.; Mashiguchi, K.; Inoue, K.; Yoshitake, Y.; Yamaoka, S.; Nishihama, R.; Kawaide, H.; Nakajima, M.; Yamaguchi, S.; Kohchi, T.
10.1101/2023.05.04.539458 — plant biology — Posted on 2023-05-08
3510 Efficient reliability analysis of spatially resolved transcriptomics at varying resolutions using SpaSEG
Bai, Y.; Guo, X.; Liu, K.; Zheng, B.; Wang, Y.; Luo, Q.; Yin, J.; Wu, L.; Li, Y.; Zhang, Y.; Chen, A.; Xu, X.; Jin, X.
10.1101/2022.11.16.516728 — bioinformatics — Posted on 2023-05-08
3511 Assessment of Storm Impact on Coral Reef Structural Complexity
Yuval, M.; Pearl, N.; Tchernov, D.; Martinez, S.; Loya, Y.; Bar-Massada, A.; Treibitz, T.
10.1101/2022.12.04.519015 — ecology — Posted on 2023-05-08
3513 Downregulation of the silent potassium channel Kv8.1 increases ALS motor neuron vulnerability
Huang, X.; Lee, S.; Kawaguchi, R.; Wiskow, O.; Ghosh, S.; Frost, D.; Perrault, L.; Pandey, R.; Chen, K.; Klim, J. R.; Boivin, B.; Hermawan, C.; Livak, K. J.; Geschwind, D.; Wainger, B. J.; Eggan, K.; Bean, B. P.; Woolf, C.
10.1101/2023.05.07.539778 — neuroscience — Posted on 2023-05-08
3515 scifAI: Explainable machine learning for profiling the immunological synapse and functional characterization of therapeutic antibodies
Shetab Boushehri, S.; Essig, K.; Chlis, N.-K.; Herter, S.; Bacac, M.; Theis, F. J.; Glasmacher, E.; Marr, C.; Schmich, F.
10.1101/2022.10.24.513494 — bioinformatics — Posted on 2023-05-08
3518 A direct fiber approach to model sclera collagen architecture and biomechanics
Ji, F.; Bansal, M.; Wang, B.; Hua, Y.; Islam, M. R.; Matuschke, F.; Axer, M.; Sigal, I. A.
10.1101/2022.11.20.517259 — bioengineering — Posted on 2023-05-08
3520 Dysfunctional effector memory CD8 T cells in the bronchoalveolar compartment of people living with HIV
Mthembu, M.; Claassen, H.; Khuzwayo, S.; Voillet, V.; Naidoo, A.; Nyamande, K.; Khan, D. F.; Maharaj, P.; Mitha, M.; Mhlane, Z.; Karim, F.; Andersen-Nissen, E.; Ndung'u, T.; Pollara, G.; Wong, E. B.
10.1101/2023.05.05.539571 — immunology — Posted on 2023-05-08
3521 Multi-Omics Regulatory Network Inference in the Presence of Missing Data
Henao, J. D.; Lauber, M.; Azevedo, M.; Grekova, A.; Theis, F. J.; List, M.; Ogris, C.; Schubert, B.
10.1101/2022.04.14.488153 — systems biology — Posted on 2023-05-08
3525 Genome-scale analysis of interactions between genetic perturbations and natural variation
Hale, J. J.; Matsui, T.; Goldstein, I.; Mullis, M.; Roy, K. R.; Ville, C. N.; Miller, D.; Wang, C.; Reynolds, T.; Steinmetz, L. M.; Levy, S. F.; Ehrenreich, I.
10.1101/2023.05.06.539663 — genetics — Posted on 2023-05-07
3528 Aggregating network inferences: towards useful networks
CHAMPION, C.; MOMAL, R.; Le Chatelier, E.; Mariadassou, M.; Berland, M.
10.1101/2023.05.05.539529 — bioinformatics — Posted on 2023-05-07
3529 Site-Specific Phosphorylation of ZYG-1 Regulates ZYG-1 Stability and Centrosome Number
Medley, J. C.; Yim, N.; DiPanni, J.; Schaffou, B.; Sebou, B.; Cramer, E.; Wu, C.; Kabara, M.; Song, M. H.
10.1101/2023.05.07.539463 — cell biology — Posted on 2023-05-07
3530 DNA double-strand break-capturing nuclear envelope tubules drive DNA repair
Shokrollahi, M.; Stanic, M.; Hundal, A.; Chan, J. N. Y.; Urman, D.; Hakem, A.; Garcia, R. E.; Hao, J.; Maass, P. G.; Dickson, B. C.; Hande, M. P.; Pujana, M. A.; Hakem, R.; Mekhail, K.
10.1101/2023.05.07.539750 — molecular biology — Posted on 2023-05-07
3533 An Excitatory Projection from the Basal Forebrain to the Ventral Tegmental Area Underlying Anorexia-like Phenotypes
Cai, J.; Xu, Y.; Jiang, Z.; Jiang, Y.; Young, C.; Li, H.; Otiz-Guzman, J.; Zhuo, Y.; Li, Y.; Xu, Y.; Arenkiel, B. R.; Tong, Q.
10.1101/2023.05.05.539422 — neuroscience — Posted on 2023-05-07
3534 The Association between Commensal Flagellated Bacteria and Cardiovascular Benefits in Humans
Yiu, J. H. C.; Cai, J.; Cheung, S. W.; Chin, K. T. C.; Chan, C. F.; Ma, E. S. C.; Sharma, R.; Dorweiler, B.; Woo, C. W. H.
10.1101/2023.05.04.539500 — systems biology — Posted on 2023-05-07
3536 Gastrointestinal transit mathematical model in mice treated with antibiotics
Maskawa, R.; Takayasu, L.; Takayasu, H.; Watanabe, K.; Takemine, S.; Kakimoto, T.; Takeshita, K.; Narushima, S.; Suda, W.; Takayasu, M.
10.1101/2023.05.05.539495 — physiology — Posted on 2023-05-07
3537 Deconvolution Of Hematopoietic Stem/Progenitor Cell Signaling Predicts Inflammatory Niche Remodeling To Be A Determinant Of Tissue Failure And Outcome In Human AML
Chen, L.; Pronk, E.; van Dijk, C.; Bian, Y.; Feyen, J.; van Tienhoven, T.; Yildirim, M.; Pisterzi, P.; de Jong, M.; Bastidas, A.; Hoogenboezem, R.; Wevers, C.; Bindels, E.; Lowenberg, B.; Cupedo, T.; Sanders, M. A.; Raaijmakers, M.
10.1101/2023.05.05.539525 — cancer biology — Posted on 2023-05-07
3539 A Comparative Study of Protein Structure Prediction Tools for Challenging Targets: Snake Venom Toxins
Kalogeropoulos, K.; Bohn, M.-F.; Jenkins, D. E.; Ledergerber, J.; Soerensen, C. V.; Hofmann, N.; Wade, J.; Fryer, T. J.; Nguyen, G. T. T.; auf dem Keller, U.; Laustsen, A. H.; Jenkins, T. P.
10.1101/2023.05.05.539526 — bioinformatics — Posted on 2023-05-07
3541 RaMALDI: enabling simultaneous Raman and MALDI imaging of the same tissue section
Yang, E.; Kim, J. H.; Tressler, C. M.; Shen, X. E.; Brown, D. R.; Johnson, C. C.; Barman, I.; Glunde, K.
10.1101/2023.05.07.539107 — bioengineering — Posted on 2023-05-07
3542 The Interplay between Mutagenesis and Extrachromosomal DNA Shapes Urothelial Cancer Evolution
Nguyen, D. D.; Hooper, W. F.; Chu, T. R.; Geiger, H.; Shelton, J. M.; Shah, M.; Goldstein, Z. R.; Winterkorn, L.; Sigouros, M.; Manohar, J.; Moyer, J.; Wilkes, D.; Singh, R. R.; Liu, W.; Sboner, A.; Tagawa, S. T.; Nanus, D. M.; Nauseef, J. T.; Sternberg, C. N.; Molina, A. M.; Scherr, D. S.; Inghirami, G. G.; Mosquera, J. M.; Elemento, O.; Robine, N.; Faltas, B. M.
10.1101/2023.05.07.538753 — genomics — Posted on 2023-05-07
3544 Maintaining long-term genetic gain using a segment-stacking algorithm
Villiers, K.; Voss-Fels, K. P.; Dinglasan, E.; Jacobs, B.; Hickey, L.; Hayes, B. J.
10.1101/2023.05.05.539510 — genetics — Posted on 2023-05-07
3548 Increased hyaluronan by naked mole-rat HAS2 extends lifespan in mice
Zhang, Z.; Tian, X.; Lu, J. Y.; Boit, K.; Ablaeva, J.; Zakusilo, F. T.; Emmrich, S.; Firsanov, D.; Rydkina, E.; Biashad, S. A.; Lu, Q.; Tyshkovskiy, A.; Gladyshev, V. N.; Horvath, S.; Seluanov, A.; Gorbunova, V.
10.1101/2023.05.04.539405 — physiology — Posted on 2023-05-07
3549 Diving dinosaurs? Caveats on the use of bone compactness and pFDA for inferring lifestyle
Myhrvold, N. P.; Sereno, P. C.; Baumgart, S. L.; Vidal, D.; Fish, F. E.; Henderson, D. M.; Saitta, E. T.
10.1101/2023.05.04.539484 — paleontology — Posted on 2023-05-07
3559 Synergistic computational and experimental studies of a phosphoglycosyltransferase membrane/ligand ensemble
Majumder, A.; Vuksanovic, N.; Ray, L. C.; Bernstein, H. M.; Allen, K. N.; Imperiali, B.; Straub, J. E.
10.1101/2023.05.07.539694 — biochemistry — Posted on 2023-05-07
3560 A Machine Learning One-Class Logistic Regression Model to Predict Stemness in Single Cell Transcriptomics and Spatial Omics Datasets
Segato, F. D.; Marcao, M.; Ben-Cheikh, B.; Nikulina, N.; Omotoso, A.; Burnett, D.; Coelho, P.; Badal, S.; Hurley, J.; Gomez, C.; Phan-Everson, T.; Ong, G.; Martelotto, L.; Lewis, Z. R.; George, S.; Braubach, O.; Malta, T.; Plummer, J. T.
10.1101/2023.05.04.539461 — genomics — Posted on 2023-05-07
3561 Reduced frequency of clonal hematopoiesis in Parkinson's disease
Sun, S.; Sproviero, D.; Payan-Gomez, C.; Huang, Z.; Hoeijmakers, J. H. J.; Maslov, A. Y.; Mastroberardino, P. G.; Vijg, J.
10.1101/2023.05.04.539397 — genetics — Posted on 2023-05-07
3564 Serum iron and hepatic transferrin receptor expression are circadian-regulated
Bennett, C.; Pettikiriarachchi, A.; McLean, A. R. D.; Harding, R.; Blewitt, M. E.; Seillet, C.; Pasricha, S.-R.
10.1101/2023.05.07.539729 — molecular biology — Posted on 2023-05-07
3565 A transmission chain linking Mycobacterium ulcerans with Aedes notoscriptus mosquitoes, possums and human Buruli ulcer cases in southeastern Australia
Mee, P. T.; Buultjens, A. H.; Oliver, J.; Brown, K.; Crowder, J. C.; Porter, J. L.; Hobbs, E. C.; Judd, L. M.; Taiaroa, G.; Puttharak, N.; Williamson, D. A.; Blasdell, K. R.; Tay, E. L.; Feldman, R.; Muzari, M. O.; Sanders, C.; Larsen, S.; Crouch, S. R.; Johnson, P. P.; Wallace, J. R.; Price, D. J.; Hoffmann, A. A.; Gibney, K. B.; Stinear, T. P.; Lynch, S. E.
10.1101/2023.05.07.539718 — microbiology — Posted on 2023-05-07
3566 Pantailocins: Phage-derived Bacteriocins from Pantoea ananatis and Pantoea stewartii subsp. indologenes
Stice, S.; Jan, H.-H.; Chen, H.-C.; Nwosu, L.; Shin, G. Y.; Weaver, S.; Coutinho, T.; Kvitko, B.; Baltrus, D. A.
10.1101/2023.05.07.539753 — microbiology — Posted on 2023-05-07
3568 A digital twin of bacterial metabolism during cheese production
Lecomte, M.; Cao, W.; Aubert, J.; Sherman, D. J.; Falentin, H.; Frioux, C.; Labarthe, S.
10.1101/2023.05.05.539417 — bioinformatics — Posted on 2023-05-07
3569 CREID- A ChemoReceptor-Effector Interaction Database
Peta, V. J.; Hartman, T.; Aryal, S.; Gurung, B. S.; Singh, R.; Haas, S.; Bomgni, A.; Do, T.; Dhiman, S. J.; Gadhamshetty, V.; Gnimpieba, E.
10.1101/2023.05.04.539426 — bioengineering — Posted on 2023-05-07
3570 Conformation-specific synthetic antibodies discriminate multiple functional states of the ion channel CorA
Erramilli, S. K.; Dominik, P. K.; Deneka, D.; Tokarz, P. P.; Kim, S. S.; Reddy, B. G.; Skrobek, B. M.; Dalmas, O.; Perozo, E.; Kossiakoff, A. A.
10.1101/2023.05.07.539746 — biochemistry — Posted on 2023-05-07
3571 Sea-ice melt determines seasonal phytoplankton dynamics and delimits the habitat of temperate Atlantic taxa as the Arctic Ocean atlantifies
Oldenburg, E.; Popa, O.; Wietz, M.; von Appen, W.-J.; Torres-Valdes, S.; Bienhold, C.; Ebenhoeh, O.; Metfies, K.
10.1101/2023.05.04.539293 — ecology — Posted on 2023-05-07
3572 Signatures of antibiotic tolerance and persistence in response to divergent stresses
Wang, H.; McElfresh, G.; Wijesuriya, N.; Podgorny, A.; Hecht, A. D.; Ray, C. J.
10.1101/2023.02.05.527212 — microbiology — Posted on 2023-05-07
3573 Multiomics Analyses Reveal Dynamic Bioenergetic Pathways and Functional Remodeling of the Heart During Intermittent Fasting
Arumugam, T. V.; Alli-Shaik, A.; Liehn, E. A.; Selvaraji, S.; Poh, L.; Rajeev, V.; Cho, Y.; Cho, Y.; Kim, J.; Kim, J.; Swa, H. L. F.; Hao, D. T. Z.; Ratttanasopa, C.; Fann, D. Y.-W.; Mayan, D. C.; Ng, G. Y.-Q.; Baik, S.-H.; Mallilankaraman, K.; Gelderblom, M.; Drummond, G. R.; Sobey, C. G.; Kennedy, B. K.; Singaraja, R. R.; Mattson, M. P.; Jo, D.-G.; Gunaratne, J.
10.1101/2021.03.04.433999 — systems biology — Posted on 2023-05-07
3574 Critical role of down-regulated in adenoma bicarbonate transporter in linaclotide stimulated intestinal bicarbonate secretion
Sarthi, J. B.; Trumbull, A. M.; Abazari, S. M.; van Unen, V.; Chan, J. E.; Joo, N. S.; Jiang, Y.; Kuo, C.; Sellers, Z. M.
10.1101/2023.05.05.539132 — physiology — Posted on 2023-05-07
3575 Overlapping stimulons arising in response to divergent stresses in Escherichia coli
Wang, H.; McElfresh, G.; Wijesuriya, N.; Podgorny, A.; Hecht, A. D.; Ray, J. C. J.
10.1101/2021.12.17.473201 — bioinformatics — Posted on 2023-05-07
3576 German-wide Malaise trap metabarcoding estimates over 33,000 insect species
Buchner, D.; Beermann, A. J.; Hoerren, T. P. B.; Enss, J.; Frenzel, M.; Li, Y.; Mueller, J.; Pauls, S. U.; Sorg, M.; LTER-D consortium, ; Haase, P.; Leese, F.
10.1101/2023.05.04.539402 — ecology — Posted on 2023-05-07
3577 The temporal progression of immune remodeling during metastasis.
McGinnis, C. S.; Mao, Z.; Reticker-Flynn, N. E.; Winkler, J.; Satpathy, A. T.
10.1101/2023.05.04.539153 — immunology — Posted on 2023-05-07
3578 Linked CD4+/CD8+ T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression
Dolina, J. S.; Lee, J.; Brightman, S. E.; McArdle, S.; Hall, S. M.; Thota, R. R.; Lanka, M.; Premlal, A. L. R.; Greenbaum, J. A.; Cohen, E. E. W.; Peters, B.; Schoenberger, S. P.
10.1101/2023.05.06.539290 — immunology — Posted on 2023-05-07
3579 Soluble antigen arrays improve the efficacy and safety of peptide-based tolerogenic immunotherapy
Firdessa Fite, R.; Johnson, S. N.; Leon, M. A.; Sestak, J. O.; Berkland, C.; Creusot, R. J.
10.1101/2023.05.05.539161 — immunology — Posted on 2023-05-07
3582 Inferring secretory and metabolic pathway activity from omic data with secCellFie
Masson, H. O.; Samoudi, M.; Robinson, C. M.; Kuo, C.-C.; Weiss, L.; Shams Ud Doha, K.; Campos, A.; Tejwani, V.; Dahodwala, H.; Menard, P.; Voldborg, B. G.; Sharfstein, S.; Lewis, N.
10.1101/2023.05.04.539316 — systems biology — Posted on 2023-05-07
3586 Maize COI1 quadruple-knockout mutants exhibit elevated DELLA protein accumulation, stunted growth, and reduced photosynthetic efficiency
Feiz, L.; Shyu, C.; Wu, S.; Ahern, K. R.; Gull, I.; Rong, Y.; Artymowicz, C. J.; Pineros, M. A.; Fei, Z.; Brutnell, T. P.; Jander, G.
10.1101/2023.04.21.537853 — plant biology — Posted on 2023-05-07
3587 Genetic profiling of Plasmodium ovale wallikeri relapses with microsatellite markers and whole-genome sequencing
Joste, V.; Colard-Itte, E.; Guillochon, E.; Ariey, F.; Coppee, R.; Clain, J.; Houze, S.; French National Reference Center for Imported Malaria Study Group,
10.1101/2023.02.01.526392 — microbiology — Posted on 2023-05-07
3589 OME-Zarr: a cloud-optimized bioimaging file format with international community support
Moore, J.; Basurto-Lozada, D.; Besson, S.; Bogovic, J.; Bragantini, J.; Brown, E. M.; Burel, J.-M.; Casas Moreno, X.; de Medeiros, G.; Diel, E. E.; Gault, D.; Ghosh, S. S.; Gold, I.; Halchenko, Y. O.; Hartley, M.; Horsfall, D.; Keller, M. S.; Kittisopikul, M.; Kovacs, G.; Küpcü Yoldas, A.; Kyoda, K.; le Tournoulx de la Villegeorges, A.; Li, T.; Liberali, P.; Lindner, D.; Linkert, M.; Lüthi, J.; Maitin-Shepard, J.; Manz, T.; Marconato, L.; McCormick, M.; Lange, M.; Mohamed, K.; Moore, W.; Norlin, N.; Ouyang, W.; Özdemir, B.; Palla, G.; Pape, C.; Pelkmans, L.; Pietzsch, T.; Preibisch, S.; Pr
10.1101/2023.02.17.528834 — bioinformatics — Posted on 2023-05-07
3595 Evolution in abiotic environments shapes coexistence between two spider mite species
Fragata, I.; Godinho, D. P.; Rodrigues, L. R.; Cruz, M. A.; Zele, F.; Godoy, O.; Magalhaes, S.
10.1101/2023.05.06.539716 — evolutionary biology — Posted on 2023-05-07
3597 A disease-associated gene desert orchestrates macrophage inflammatory responses via ETS2
Stankey, C. T.; Bourges, C.; Turner-Stokes, T.; Piedade, A. P.; Palmer-Jones, C.; Papa, I.; Silva dos Santos, M.; Randzavola, L. O.; Speidel, L.; Parkes, E. C.; Edwards, W.; Rochford, A. P.; Murray, C.; MacRae, J. I.; Skoglund, P.; Wallace, C.; Cader, M. Z.; Thomas, D. C.; Lee, J. C.
10.1101/2023.05.05.539522 — immunology — Posted on 2023-05-07
3601 Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
Hofman, D. A.; Ruiz-Orera, J.; Yannuzzi, I.; Murugesan, R.; Brown, A.; Clauser, K. R.; Condurat, A. L.; van Dinter, J. T.; Engels, S. A. G.; Goodale, A.; van der Lugt, J.; Abid, T.; Wang, L.; Zhou, K. N.; Vogelzang, J.; Ligon, K. L.; Phoenix, T. N.; Roth, J. A.; Root, D. E.; Hubner, N.; Golub, T. R.; Bandopadhayay, P.; van Heesch, S.; Prensner, J. R.
10.1101/2023.05.04.539399 — cancer biology — Posted on 2023-05-06
3602 Lactate and Immunomagnetic-purified iPSC-derived Cardiomyocytes Generate Comparable Engineered Cardiac Tissue Constructs
Rossler, K. J.; de Lange, W.; Mann, M. W.; Aballo, T. J.; Melby, J. A.; Zhang, J.; Kim, G.; Bayne, E. F.; Zhu, Y.; Farrell, E. T.; Kamp, T. J.; Ralphe, J. C.; Ge, Y.
10.1101/2023.05.05.539642 — molecular biology — Posted on 2023-05-06
3604 Mapping the Morphology of DNA on Carbon Nanotube-Based Sensors in Solution using X-ray Scattering Interferometry
Rosenberg, D. J.; Cunningham, F. J.; Hubbard, J. D.; Goh, N. S.-Y.; Wang, J. W.-T.; Hayman, E. B.; Hura, G. L.; Landry, M. P.; Pinals, R. L.
10.1101/2023.05.04.539504 — biophysics — Posted on 2023-05-06
3605 Conserved cardiolipin-mitochondrial ADP/ATP carrier interactions assume distinct structural and functional roles that are clinically relevant
Senoo, N.; Chinthapalli, D. K.; Baile, M. G.; Golla, V. K.; Saha, B.; Ogunbona, O. B.; Saba, J. A.; Munteanu, T.; Valdez, Y.; Whited, K.; Chorev, D.; Alder, N.; May, E. R.; Robinson, C. V.; Claypool, S. M.
10.1101/2023.05.05.539595 — biochemistry — Posted on 2023-05-06
3608 Human macroH2A1 drives nucleosome dephasing and genome instability in histone-humanized yeast
Haase, M. A. B.; Lazar Stefanita, L.; Olafsson, G.; Wudzinska, A.; Shen, M. J.; Truong, D. M.; Boeke, J. D.
10.1101/2023.05.06.538725 — genetics — Posted on 2023-05-06
3610 B. subtilis MutS2 splits stalled ribosomesinto subunits without mRNA cleavage
Park, E.; Mackens-Kiani, T.; Berhane, R.; Esser, H.; Erdenebat, C.; Burroughs, A. M.; Berninghausen, O.; Aravind, L.; Beckmann, R.; Green, R.; Buskirk, A. R.
10.1101/2023.05.05.539626 — molecular biology — Posted on 2023-05-06
3612 Apoptotic signaling clears engineered Salmonella in an organ-specific manner
Abele, T. J.; Billman, Z. P.; Li, L.; Harvest, C. K.; Bryan, A. K.; Magalski, G. R.; Lopez, J. P.; Larson, H. N.; Yin, X.-M.; Miao, E. A.
10.1101/2023.05.06.539681 — immunology — Posted on 2023-05-06
3613 A longitudinal single-cell therapeutic atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease
Thomas, T.; Rich-Griffin, C.; Pohin, M.; Friedrich, M.; Aschenbrenner, D.; Pakpoor, J.; Jainarayanan, A.; Voda, A.-I.; Sanches Peres, R.; Nee, E.; Sathananthan, D.; Kotliar, D.; Turner, J.; Nayar, S.; Zhang, F.; Jonsson, A.; Brenner, M.; Raychaudhuri, S.; Kulicke, R.; Ramsdell, D.; Stransky, N.; Pagliarini, R.; Belecki, P.; Spies, N.; Wagner, A.; Walsh, A.; Coles, M.; Jostins-Dean, L.; Powrie, F.; Filer, A.; Travis, S.; Uhlig, H.; Dendrou, C.; Buckley, C.
10.1101/2023.05.05.539635 — immunology — Posted on 2023-05-06
3616 CRISPR/Cas9-mediated mutagenesis of the Asian Citrus Psyllid, Diaphorina citri
Chaverra-Rodriguez, D.; Bui, M.; Gilleland, C. L.; Rasgon, J. L.; Akbari, O.
10.1101/2023.05.05.539615 — bioengineering — Posted on 2023-05-06
3619 Driving and suppressing the human language network using large language models
Tuckute, G.; Sathe, A.; Srikant, S.; Taliaferro, M.; Wang, M.; Schrimpf, M.; Kay, K.; Fedorenko, E.
10.1101/2023.04.16.537080 — neuroscience — Posted on 2023-05-06
3620 A quantitative theory for genomic offset statistics
Gain, C.; Rhone, B.; CUBRY, P.; Salazar, I.; Forbes, F.; Vigouroux, y.; Jay, F.; Francois, O.
10.1101/2023.01.02.522469 — evolutionary biology — Posted on 2023-05-06
3621 The distribution, phenology, host range and pathogen prevalence of Ixodes ricinus in France: a systematic map and narrative review
Perez, G.; Bournez, L.; Boulanger, N.; Fite, J.; Livoreil, B.; McCoy, K. D.; Quillery, E.; Rene-Martellet, M.; Bonnet, S. I.
10.1101/2023.04.18.537315 — ecology — Posted on 2023-05-06
3624 Calcium-triggered DNA-mediated membrane fusion in synthetic cells
Hsu, Y.-Y.; Chen, S. J.; Bernal-Chanchavac, J.; Moghimianavval, H.; Stephanopoulos, N.; Liu, A. P.
10.1101/2023.05.06.539684 — synthetic biology — Posted on 2023-05-06
3626 Protein interactome homeostasis through an N-recognin E3 ligase is a vulnerability in aneuploid cancer
Kathiresan, M.; Animesh, S.; Morris, R.; Kreuzer, J.; Krushna, P.; Shi, L.; Merritt, J.; Yin, X.; Benes, C. H.; Bardeesy, N.; Haas, W.
10.1101/2023.05.04.539299 — cancer biology — Posted on 2023-05-06
3627 Direct androgen receptor regulation of sexually dimorphic gene expression in the mammalian kidney
Xiong, L.; Liu, J.; Han, S. Y.; Koppitch, K.; Guo, J.-J.; Rommelfanger, M.; Gao, F.; Hallgrimsdottir, I. B.; Pachter, L.; Kim, J.; MacLean, A. L.; McMahon, A.
10.1101/2023.05.06.539585 — developmental biology — Posted on 2023-05-06
3631 Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated from natural crystals using MHz-SFX
Williamson, L. J.; Galchenkova, M.; Best, H. L.; Bean, R. J.; Munke, A.; Awel, S.; Pena, G.; Knoska, J.; Schubert, R.; Doerner, K.; Park, H.-W.; Bideshi, D. K.; Henkel, A.; Kremling, V.; Klopprogge, B.; Lloyd-Evans, E.; Young, M.; Valerio, J.; Kloos, M.; Sikorski, M.; Mills, G.; Bielecki, J.; Kirkwood, H.; Kim, C.; de Wijn, R.; Lorenzen, K.; Xavier, P. L.; Rahmani, A.; Gelisio, L.; Yefanov, O.; Mancuso, A. P.; Federici, B.; Chapman, H. N.; Crickmore, N.; Rizkallah, P. J.; Berry, C.; Oberthur, D.
10.1101/2022.01.14.476343 — biochemistry — Posted on 2023-05-06
3636 Local changes in potassium ions modulate dendritic integration
Nordentoft, M. S.; Papoutsi, A.; Takahashi, N.; Heltberg, M. S.; Jensen, M. H.; Rasmussen, R. N.
10.1101/2023.05.06.539205 — neuroscience — Posted on 2023-05-06
3638 ASTK: a machine learning-based integrative software for alternative splicing analysis
Huang, S.; He, J.; Yu, L.; Guo, J.; Sun, Z.; Cheng, L.; Chen, X.; Ji, X.; Zhang, Y.
10.1101/2023.01.03.522470 — bioinformatics — Posted on 2023-05-05
3639 Up-regulation of cholesterol synthesis pathways and limited neurodegeneration in a knock-in Sod1 mutant mouse model of ALS.
Dominov, J. A.; Madigan, L. A.; Whitt, J. P.; Rademacher, K. L.; Webster, K. M.; Zhang, H.; Banno, H. A.; Tang, S.; Zhang, Y.; Wightman, N.; Shychuck, E. M.; Page, J.; Weiss, A.; Kelly, K.; Kucukural, A. A.; Brodsky, M. H.; Jaworski, A.; Fallon, J. R.; Lipscombe, D.; Brown, R. H.
10.1101/2023.05.05.539444 — neuroscience — Posted on 2023-05-05
3641 Refinement of Multiconformer Ensemble Models from Multi-temperature X-ray Diffraction Data
Du, S.; Wankowicz, S. A.; Yabukarski, F.; Doukov, T.; Herschlag, D.; Fraser, J. S.
10.1101/2023.05.05.539620 — biophysics — Posted on 2023-05-05
3642 Protein Engineering for Thermostability through Deep Evolution
Chu, H.; Tian, Z.; Hu, L.; Zhang, H.; Chang, H.; Bai, J.; Liu, D.; Cheng, J.; Jiang, H.
10.1101/2023.05.04.539497 — bioinformatics — Posted on 2023-05-05
3644 Nanomolar range of FAM237B can activate receptor GPR83
Li, H.-Z.; Wang, Y.-F.; Hu, W.-F.; Liu, Y.-L.; Xu, Z.-G.; Guo, Z.-Y.
10.1101/2023.05.04.539513 — biochemistry — Posted on 2023-05-05
3645 Optimization of Cas12a for multiplexed genome-scale transcriptional activation
Griffith, A. L.; Zheng, F.; McGee, A. V.; Miller, N.; Szegletes, Z. M.; Reint, G.; Gademann, F.; Nwolah, I.; Hegde, M.; Liu, Y. V.; Goodale, A.; Doench, J. G.
10.1101/2023.04.13.536783 — genomics — Posted on 2023-05-05
3646 Discordant calls across genotype discovery approaches elucidate variants with systematic errors
Atkinson, E. G.; Artomov, M.; Loboda, A. A.; Rehm, H. L.; MacArthur, D. G.; Karczewski, K. J.; Neale, B. M.; Daly, M. J.
10.1101/2022.03.24.485707 — genomics — Posted on 2023-05-05
3647 Climate Change Factors Interactively Shift Peatland Functional Microbial Composition in an Ecosystem Warming Experiment
Kilner, C. L.; Carrell, A. A.; Wieczynski, D. J.; Votzke, S.; DeWitt, K.; Yammine, A.; Shaw, J.; Pelletier, D. A.; Weston, D. J.; Gibert, J. P.
10.1101/2023.03.06.531192 — ecology — Posted on 2023-05-05
3650 Context transcription factors establish cooperative environments and mediate enhancer communication
Kribelbauer, J. F.; Pushkarev, O.; Gardeux, V.; Russeil, J.; van Mierlo, G.; Deplancke, B.
10.1101/2023.05.05.539543 — molecular biology — Posted on 2023-05-05
3651 A novel bacterial signal transduction system specifically senses and responds to peptidoglycan damage
Yin, J.; Xu, C.; Hu, X.; Zhang, T.; Liang, Y.; Sun, Y.; Zhen, X.; Zhu, Y.; Luo, Y.; Shen, P.; Cheng, D.; Sun, Y.; Cai, J.; Meng, Q.; Zhu, T.; Wan, F.; Gao, H.; Yu, Z.
10.1101/2023.05.05.539549 — microbiology — Posted on 2023-05-05
3652 Shigella O-specific polysaccharide functional IgA responses mediate protection against shigella infection in an endemic high-burden setting
Bernshtein, B.; Kelly, M.; Cizmeci, D.; Zhiteneva, J. A.; Macvicar, R.; Kamruzzaman, M.; Bhuiyan, T. R.; Chowdhury, F.; Khan, A. I.; Qadri, F.; Charles, R. C.; Xu, P.; Kovac, P.; Kaminski, R. W.; Alter, G.; Ryan, E. T.
10.1101/2023.05.04.539451 — immunology — Posted on 2023-05-05
3653 Dysfunctional effector memory CD8 T cells in the bronchoalveolar compartment of people living with HIV
Mthembu, M.; Claassen, H.; Khuzwayo, S.; Voillet, V.; Naidoo, A.; Nyamande, K.; Khan, D. F.; Maharaj, P.; Mitha, M.; Mhlane, Z.; Karim, F.; Andersen-Nissen, E.; Ndung'u, T.; Pollara, G.; Wong, E. B.
10.1101/2023.05.05.539571 — immunology — Posted on 2023-05-05
3655 The infralimbic and prelimbic cortical areas bidirectionally regulate safety learning during normal and stress conditions.
Felix-Ortiz, A. C.; Terrell, J. M.; Gonzalez, C.; Msengi, H. D.; Ramos, A. R.; Boggan, M. B.; Lopez-Pesina, S. M.; Magalhaes, G.; Burgos-Robles, A.
10.1101/2023.05.05.539516 — neuroscience — Posted on 2023-05-05
3658 PROTEOMICS OF HYPOTHERMIC ADAPTATION REVEALS THAT RBM3 ENHANCES MITOCHONDRIAL METABOLISM AND MUSCLE STEM-CELL DIFFERENTIATION
Ramanathan, A.; Dey, P.; Rajalaxmi, S.; Thakur, P. S.; Hashmi, M. A.; Lal, H.; Saini, N.; Muralidharan, S.; Math, R. G. H.; Saha, P.; Pundlik, S. S.; Singh, N.
10.1101/2023.05.05.539524 — biochemistry — Posted on 2023-05-05
3660 Characterizing the landscape of gene expression variance in humans
Wolf, S.; Melo, D.; Garske, K. M.; Pallares, L. F.; Lea, A. J.; Ayroles, J. F.
10.1101/2022.11.15.516646 — genomics — Posted on 2023-05-05
3661 Socio-cultural practices may have affected sexual dimorphism in stature in Early Neolithic Europe
Cox, S. L.; Nicklisch, N.; Francken, M.; Wahl, J.; Meller, H.; Haak, W.; Alt, K. W.; Rosenstock, E.; Mathieson, I.
10.1101/2023.02.21.529406 — genetics — Posted on 2023-05-05
3669 Impairments in hippocampal oscillations accompany the loss of LTP induced by GIRK activity blockade
Contreras, A.; Djebari, S.; Temprano, S.; Munera, A.; Gruart, A. D.; Delgado-Garcia, J. M.; Jimenez-Diaz, L.; Navarro-Lopez, J. D.
10.1101/2023.05.05.539539 — neuroscience — Posted on 2023-05-05
3670 Predicting Parkinson's disease progression using MRI-based white matter radiomic biomarker and machine learning: a reproducibility and replicability study
Arafe, M.; Bhagwat, N. P.; Chatelain, Y.; Dugre, M.; Sokolowski, A.; Wang, M.; Xiao, Y.; Sharp, M.; Poline, J.-B.; Glatard, T.
10.1101/2023.05.05.539590 — neuroscience — Posted on 2023-05-05
3672 Evolutionary adaptation from hydrolytic to oxygenolytic catalysis
Bui, S.; Gil-Guerrero, S.; van der Linden, P.; Carpentier, P.; Ceccarelli, M.; Jambrina, P. G.; Steiner, R. A.
10.1101/2023.05.05.539528 — biochemistry — Posted on 2023-05-05
3674 Opposing roles for TGFbeta and BMP-signaling during nascent alveolar differentiation in the developing human lung
Frum, T.; Hsu, P. P.; Hein, R. F. C.; Conchola, A. S.; Zhang, C. J.; Utter, O. R.; Anand, A.; Zhang, Y.; Clark, S. G.; Glass, I.; Sexton, J. Z.; Spence, J. R.
10.1101/2023.05.05.539573 — developmental biology — Posted on 2023-05-05
3677 Neuro-Environmental Interactions: a time sensitive matter
Invernizzi, A.; Renzetti, S.; Rechtman, E.; Ambrosi, C.; Mascaro, L.; Corbo, D.; Gasparotti, R.; Tang, C. Y.; Smith, D. R.; Lucchini, R. G.; Wright, R. O.; Placidi, D.; Horton, M. K.; Curtin, P.
10.1101/2023.05.04.539456 — neuroscience — Posted on 2023-05-05
3678 Ribosomal dysregulation: A conserved pathophysiological mechanism in human depression and mouse chronic stress.
Zhang, X.; Eladawi, M. A.; Ryan, W. G.; Fan, X.; Prevoznik, S.; Devale, T.; Ramnani, B.; Krishnamurthy, M. A.; Sibille, E.; McCullumsmith, R.; Tomoda, T.; Shukla, R.
10.1101/2023.05.04.539419 — neuroscience — Posted on 2023-05-05
3680 Sex similarities and dopaminergic differences in interval timing
Stutt, H. R.; Weber, M. A.; Cole, R. C.; Bova, A. S.; Ding, X.; McMurrin, M. S.; Narayanan, N.
10.1101/2023.05.05.539584 — neuroscience — Posted on 2023-05-05
3682 Three-dimensional characterization of medium spiny neuron heterogeneity in the adult mouse striatum
Gayden, J.; Puig, S.; Srinivasan, C.; Buck, S. A.; Gamble, M. C.; Glausier, J. R.; Tejeda, H. A.; Dong, Y.; Pfenning, A. R.; Logan, R.; Freyberg, Z.
10.1101/2023.05.04.539488 — neuroscience — Posted on 2023-05-05
3683 Dimensional clinical phenotyping using post-mortem brain donor medical records: Association with neuropathology
Vogelgsang, J. S.; Dan, S.; Lally, A. P.; Chatigny, M.; Vempatia, S.; Abston, J.; Durning, P. T.; Oakley, D. H.; McCoy, T. H.; Klengel, T.; Berretta, S.
10.1101/2023.05.04.539430 — neuroscience — Posted on 2023-05-05
3684 When population growth intensifies intergroup competition, female colobus monkeys free-ride less
Arseneau-Robar, T. J. M.; Teichroeb, J.; Macintosh, A.; Saj, T.; Glotfelty, E.; Lucci, S.; Sicotte, P.; Wikberg, E.
10.1101/2023.05.05.539387 — animal behavior and cognition — Posted on 2023-05-05
3685 Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury
Veniaminova, N. A.; Jia, Y.; Hartigan, A. M.; Huyge, T. J.; Tsai, S.-Y.; Grachtchouk, M.; Nakagawa, S.; Dlugosz, A. A.; Atwood, S. X.; Wong, S. Y.
10.1101/2023.05.05.539454 — developmental biology — Posted on 2023-05-05
3687 Sleep is required for neural network plasticity in the jellyfish Cassiopea
Abrams, M. J.; Zhang, L.; von Emster, K.; Lee, B. H.; Zeigler, H.; Jain, T.; Jafri, A.; Chen, Z.; Harland, R. J.
10.1101/2023.05.04.538973 — neuroscience — Posted on 2023-05-05
3690 Resilient functioning after childhood adversity is associated with altered structural brain network topology in adolescence.
Gonzalez-Garcia, N.; Buimer, E. E.; Moreno-Lopez, L.; Sallie, S. N.; Vasa, F.; Lim, S.; Romero-Garcia, R.; Scheuplein, M.; Whitaker, K.; Jones, P. B.; Dolan, R.; NSPN consortium, ; Fonagy, P.; Goodyer, I.; Bullmore, E.; van Harmelen, A.-L.
10.1101/2023.05.05.538901 — neuroscience — Posted on 2023-05-05
3693 Computational principles of adaptive multisensory combination in the Drosophila larva
Wong, P.; Braun, A.; Malagarriga, D.; Moehlis, J.; Moreno Bote, R.; Pouget, A.; Louis, M.
10.1101/2023.05.04.539474 — neuroscience — Posted on 2023-05-05
3696 Can motional dynamics account for the cytotoxicity of beta amyloid oligomers?
Yeh, C.-T.; Chang, H.-W.; Hsu, W.-H.; Huang, S.-J.; Wu, M.-H.; Tu, L.-H.; Lee, M.-C.; Chan, C. C. J.
10.1101/2023.05.04.539338 — biophysics — Posted on 2023-05-05
3700 netMUG: a novel network-guided multi-view clustering workflow for dissecting genetic and facial heterogeneity
Li, Z.; Melograna, F.; Hoskens, H.; Duroux, D.; Marazita, M. L.; Walsh, S.; Weinberg, S. M.; Shriver, M. D.; Müller-Myhsok, B.; Claes, P.; Van Steen, K.
10.1101/2023.05.04.539350 — bioinformatics — Posted on 2023-05-05
3703 Evaluation of a set of eggplant (Solanum melongena) lines with introgressions of S. incanum under water stress conditions
Flores-Saavedra, M.; Gramazio, P.; Vilanova, S.; Mircea, D. M.; Ruiz-Gonzalez, M. X.; Vicente, O.; Prohens, J.; Plazas, M.
10.1101/2023.05.04.539376 — genetics — Posted on 2023-05-05
3710 Sea-ice melt determines seasonal phytoplankton dynamics and delimits the habitat of temperate Atlantic taxa as the Arctic Ocean atlantifies
Oldenburg, E.; Popa, O.; Wietz, M.; von Appen, W.-J.; Torres-Valdes, S.; Bienhold, C.; Ebenhoeh, O.; Metfies, K.
10.1101/2023.05.04.539293 — ecology — Posted on 2023-05-05
3713 SUMOylation of MFF is required for stress-induced mitochondrial fission
Seager, R.; Shree Ramesh, N.; Cross, S.; Guo, C.; Wilkinson, K.; Henley, J.
10.1101/2023.05.05.539603 — cell biology — Posted on 2023-05-05
3714 Keratin isoform shifts modulate motility signals during wound healing
Nanes, B. A.; Bhatt, K.; Azarova, E.; Rajendran, D.; Isogai, T.; Dean, K. M.; Danuser, G.
10.1101/2023.05.04.538989 — cell biology — Posted on 2023-05-05
3715 Effects of TP63 Mutations on Keratinocyte Adhesion and Migration
Salois, M. N.; Gugger, J. A.; Webb, S.; Sheldon, C. E.; Parraga, S. P.; Lewitt, G. M.; Grange, D. K.; Koch, P. J.; Koster, M. I.
10.1101/2023.05.04.539104 — cell biology — Posted on 2023-05-05
3716 Circulating Microparticles: Optimization and Standardization of Isolation Protocols and Reassessment of Their Characteristics and Functions
ZHANG, C.; Hu, J.; SHI, Y.; FENG, Y.; LI, Z.; ZHANG, T.; HONG, L.; DONG, Z.; TANG, Y.; WANG, Z.; NING, G.; Huang, G.-R.
10.1101/2023.05.04.539499 — cell biology — Posted on 2023-05-05
3717 Oct4 is a gatekeeper of epithelial identity by regulating cytoskeletal dynamics in skin keratinocytes
Christofidou, E.; Tomazou, M.; Voutouri, C.; Michael, C.; Stylianopoulos, T.; Spyrou, G. M.; Strati, K.
10.1101/2023.05.05.539557 — cell biology — Posted on 2023-05-05
3720 Rapamycin-sensitive mechanisms confine the growth of fission yeast below the temperatures detrimental to cell physiology
Morozumi, Y.; Mahayot, F.; Nakase, Y.; Soong, J. X.; Yamawaki, S.; Sofyantoro, F.; Imabata, Y.; Oda, A. H.; Tamura, M.; Kofuji, S.; Akikusa, Y.; Ohta, K.; Shiozaki, K.
10.1101/2023.05.04.539340 — cell biology — Posted on 2023-05-05
3721 MskAge - An Epigenetic Biomarker of Musculoskeletal Age Derived from a Genetic Algorithm Islands Model
Green, D. C.; Reynard, L.; Henstock, J.; Reppe, S.; Gutvik, K.; Peffers, M.; Shanley, D.; Clegg, P. D.; Canty-Laird, E. G.
10.1101/2023.05.04.539347 — cell biology — Posted on 2023-05-05
3722 Coordination of actin plus-end dynamics by IQGAP1, formin, and capping protein
Pimm, M. L.; Marcin, A. G.; Haarer, B. K.; Eligio, M. A.; Henty-Ridilla, J. L.
10.1101/2023.05.04.539490 — cell biology — Posted on 2023-05-05
3723 Rme-6 integrates EGFR trafficking and signalling to regulate ERK1/2 signalosome dynamics
Smythe, E.; Alshahrani, F.; Zhu, Z.; Ferreira, F.; Maib, H.; Pruzina, S.; Robinson, D.; Murray, D. H.; McComb, A.
10.1101/2023.05.05.539436 — cell biology — Posted on 2023-05-05
3724 ILC2 cells promote lung cancer and accumulate in tumors concomitantly with immune-suppressive cells in humans and mice
Bahhar, I.; Es, Z.; Kose, O.; Turna, A.; Gunluoglu, M. Z.; Cakir, A.; Durali, D.; magnusson, f. c.
10.1101/2023.05.04.539356 — immunology — Posted on 2023-05-05
3726 Diversity of the bacterial and viral communities in the tropical horse tick, Dermacentor nitens in Colombia
Holguin-Rocha, A. F.; Calle-Tobon, A.; Vasquez, G. M.; Astete, H.; Fisher, M. L.; Tobon-Castano, A.; Velez-Tobon, G.; Maldonado-Ruiz, L. P.; Silver, K.; Park, Y.; Londono, B.
10.1101/2023.05.04.539352 — bioinformatics — Posted on 2023-05-05
3727 Behavioral Paradigm for the Evaluation of Stimulation-Evoked Somatosensory Perception Thresholds in Rats
Smith, T. J.; Wu, Y.; Cheon, C.; Khan, A. A.; Srinivasan, H.; Capadona, J. R.; Cogan, S. F.; Pancrazio, J. J.; Engineer, C. T.; Hernandez-Reynoso, A. G.
10.1101/2023.05.04.537848 — neuroscience — Posted on 2023-05-05
3729 Classification of bacterial nanowire proteins using Machine Learning and Feature Engineering model
Raya, D.; Peta, V. J.; Bomgni, A.; Duc Do, T.; Kalimuthu, J.; Salem, D. R.; Gadhamshetty, V.; Gnimpieba, E. Z.; Dhiman, S.
10.1101/2023.05.03.539336 — systems biology — Posted on 2023-05-05
3731 Molecular basis for Gβγ-mediated activation ofphosphoinositide 3-kinase γ
Chen, C.-l.; Syahirah, R.; Ravala, S.; Yen, Y.-C.; Klose, T.; Deng, Q.; Tesmer, J. J. G.
10.1101/2023.05.04.539492 — biophysics — Posted on 2023-05-05
3732 Aging Fly Cell Atlas Identifies Exhaustive Aging Features at Cellular Resolution
Lu, T.-C.; Brbic, M.; Park, Y.-J.; Jackson, T.; Chen, J.; Kolluru, S. S.; Qi, Y.; Katheder, N. S.; Cai, X. T.; Lee, S.; Chen, Y.-C.; Auld, N.; Liang, C.-Y.; Ding, S. H.; Welsch, D.; D'Souza, S.; Pisco, A. O.; Jones, R. C.; Leskovec, J.; Lai, E. C.; Bellen, H. J.; Luo, L.; Jasper, H.; Quake, S. R.; Li, H.
10.1101/2022.12.06.519355 — developmental biology — Posted on 2023-05-05
3733 Transsynaptic labeling and transcriptional control of zebrafish neural circuits
Coomer, C.; Naumova, D.; Talay, M.; Zolyomi, B.; Snell, N.; Sorkac, A.; Chanchu, J.-M.; Cheng, J.; Roman, I.; Li, J.; Robson, D.; Barnea, G.; Halpern, M. E.
10.1101/2023.04.03.535421 — neuroscience — Posted on 2023-05-05
3734 Genetic basis of expression and splicing underlying spike architecture in wheat (Triticum aestivum L.)
Yang, G.; Pan, Y.; Cui, L.; Chen, M.; Zeng, Q.; Pan, W.; Zhe, L.; Edwards, D.; Batley, J.; Han, D.; Deng, P.; Yu, H.; Henry, R. J.; Song, W.; Nie, X.
10.1101/2023.05.04.539218 — plant biology — Posted on 2023-05-05
3738 Cloud gazing: demonstrating paths for unlocking the value of cloud genomics through cross-cohort analysis
Deflaux, N.; Selvaraj, M. S.; Condon, H. R.; Mayo, K.; Haidermota, S.; Basford, M. A.; Lunt, C.; Philippakis, A. A.; Roden, D. M.; Denny, J. C.; Musick, A.; Collins, R.; Allen, N.; Effingham, M.; Glazer, D.; Natarajan, P.; Bick, A. G.
10.1101/2022.11.29.518423 — genetics — Posted on 2023-05-05
3742 Mitochondrial Sodium/Calcium Exchanger (NCLX) Regulates Basal and Starvation-Induced Autophagy Through Calcium Signaling
de Miranda Ramos, V.; Serna, J. D.; Vilas-Boas, E. A.; Cabral-Costa, J. V.; da Cunha, F. M.; Kataura, T.; Korolchuk, V. I.; Kowaltowski, A. J.
10.1101/2023.03.17.533187 — cell biology — Posted on 2023-05-05
3744 Neural responses to reconstructed target pursuits
Ogawa, Y.; Nicholas, S.; Thyselius, M.; Nowotny, T.; Knight, J. C.; Nordstrom, K.
10.1101/2023.05.03.539331 — neuroscience — Posted on 2023-05-05
3745 Functional geometry of auditory cortical resting state networks derived from intracranial electrophysiology
Banks, M. I.; Krause, B. M.; Berger, D. G.; Campbell, D. I.; Boes, A. D.; Bruss, J. E.; Kovach, C. K.; Kawasaki, H.; Steinschneider, M.; Nourski, K. V.
10.1101/2022.02.06.479292 — neuroscience — Posted on 2023-05-05
3748 Rational development of a small-molecule activator of CK1γ2 that decreases C99 and beta-amyloid levels
Bustos, V. H.; Sunkari, Y. K.; Sinha, A.; Pulina, M.; Bispo, A.; Hopkins, M.; Lam, A.; Kriegsman, S. F.; Mui, E.; Chang, E.; Jedlicki, A.; Rosenthal, H.; Flajolet, M.; Greengard, P.; Sinha, S.
10.1101/2023.04.28.538773 — pharmacology and toxicology — Posted on 2023-05-05
3749 Global and single-cell proteomics view of the co-evolution between neural progenitors and breast cancer cells in a co-culture model
Bjoernstad, O. V.; Fernandez, M. C.; Finne, K.; Winge, I.; Askeland, C.; Arnes, J. B.; Knutsvik, G.; Kleftogiannis, D.; Paulo, J. A.; Akslen, L. A.; Vethe, H.
10.1101/2023.05.03.539050 — cancer biology — Posted on 2023-05-05
3752 Reverse Engineering DNA Origami Nanostructure Designs from Raw Scaffold and Staple Sequence Lists
Shirt-Ediss, B.; Connolly, J.; Elezgaray, J.; Torelli, E.; Navarro, S. A.; Bacardit, J.; Krasnogor, N.
10.1101/2023.05.03.539261 — bioinformatics — Posted on 2023-05-05
3755 Targeted rRNA depletion enables efficient mRNA sequencing in diverse bacterial species and complex co-cultures
Heom, K. A.; Wangsanuwat, C.; Butkovich, L. V.; Tam, S. C.; Rowe, A. R.; O'Malley, M. A.; Dey, S. S.
10.1101/2023.05.04.539346 — genomics — Posted on 2023-05-05
3756 Ecological genomics in the Northern krill uncovers loci for local adaptation across ocean basins
Unneberg, P.; Larsson, M.; Olsson, A.; Wallerman, O.; Petri, A.; Bunikis, I.; Vinnere Pettersson, O.; Papetti, C.; Gislason, A.; Glenner, H.; Cartes, J. E.; Blanco-Bercial, L.; Eriksen, E.; Meyer, B.; Wallberg, A.
10.1101/2023.04.15.537050 — evolutionary biology — Posted on 2023-05-05
3758 Necrosulfonamide causes ubiquitination of PCM1 and impairs Ciliogenesis and Autophagy
Alves Nicolau, C.; Renaud, C.; Maghe, C.; Trillet, K.; Jardine, J.; Escot, S.; David, N. B.; Gavard, J.; Bidere, N.
10.1101/2023.05.05.539527 — cell biology — Posted on 2023-05-05
3759 CD28-Selective Inhibition Prolongs Non-Human Primate Kidney Transplant Survival
Lovasik, B. P.; Kim, S. C.; Higginbotham, L.; Wakwe, W.; Mathews, D. V.; Breeden, C. P.; Farris, A. B.; Larsen, C. P.; Ford, M. L.; Nadler, S.; Adams, A. B.
10.1101/2023.05.03.539333 — immunology — Posted on 2023-05-05
3760 Intranasal self-amplifying RNA SARS-CoV-2 vaccine produces protective respiratory and systemic immunity and prevents viral transmission
Jennewein, M. F.; Schultz, M. D.; Beaver, S.; Battisti, P.; Bakken, J.; Hanson, D.; Akther, J.; Mohamath, R.; Singh, J.; Cross, N.; Reed, S.; Kalange, D.; Foote, J. B.; King, R. G.; Silva-Sanchez, A.; Botta, D.; Gerhardt, A.; Casper, C.; Randall, T. D.; Lund, F. E.; Voigt, E. A.
10.1101/2022.11.10.515993 — immunology — Posted on 2023-05-05
3762 Human cortex development is shaped by molecular and cellular brain systems
Lotter, L. D.; Saberi, A.; Hansen, J. Y.; Misic, B.; Barker, G. J.; Bokde, A. L. W.; Desrivieres, S.; Flor, H.; Grigis, A.; Garavan, H.; Gowland, P.; Heinz, A.; Bruehl, R.; Martinot, J.-L.; Paillere, M.-L.; Artiges, E.; Papadopoulos Orfanos, D.; Paus, T.; Poustka, L.; Hohmann, S.; Froehner, J. H.; Smolka, M. N.; Vaidya, N.; Walter, H.; Whelan, R.; Schumann, G.; IMAGEN Consortium, ; Nees, F.; Banaschewski, T.; Eickhoff, S. B.; Dukart, J.
10.1101/2023.05.05.539537 — neuroscience — Posted on 2023-05-05
3765 Small ADP-ribosylation factor-like GTPase TITAN5 (TTN5/ARL2) is linked with the dynamic regulation of IRON-REGULATED TRANSPORTER1
Mohr, I.; Eutebach, M.; Schommen, N.; Gratz, R.; Angrand, K.; Genders, L.; Brumbarova, T.; Bauer, P.; Ivanov, R.
10.1101/2023.04.27.538571 — plant biology — Posted on 2023-05-05
3766 Orphan Drugs and Rare Diseases: Unveiling Biological Patterns through Drug Repurposing
Otero-Carrasco, B.; Romero-Brufau, S.; Alvarez-Perez, A.; Ayuso-Munoz, A.; Prieto-Santamaria, L.; Hernandez, J. P. C.-V.; Rodriguez-Gonzalez, A.
10.1101/2023.05.03.539318 — bioinformatics — Posted on 2023-05-05
3767 Spatially-resolved single-cell atlas of ascidian endostyle provides insights into the origin of vertebrate pharyngeal organs
Jiang, A.; Han, K.; Wei, J.; Su, X.; Wang, R.; Zhang, W.; Liu, X.; Qiao, J.; Liu, P.; Liu, Q.; Zhang, J.; Zhang, N.; Ge, Y.; Zhuang, Y.; Yu, H.; Wang, S.; Chen, K.; Xu, X.; Yang, H.; Fan, G.; Dong, B.
10.1101/2023.05.03.539335 — evolutionary biology — Posted on 2023-05-05
3768 Diet Induced Obesity and Diabetes Enhance Mortality and Reduces Vaccine Efficacy for SARS-CoV-2
Johnson, R.; Ardunay, J.; Hammond, H.; Logue, J.; Jackson, L.; Baracco, L.; McGrath, M.; Dillen, C.; Patel, N.; Smith, G.; Frieman, M.
10.1101/2022.10.15.512291 — microbiology — Posted on 2023-05-05
3770 Inhibition of dopamine neurons prevents incentive value encoding of a reward cue:With revelations from deep phenotyping
Iglesias, A. G.; Chiu, A. S.; Wong, J.; Campus, P.; Li, F.; Liu, Z.; Patel, S. A.; Deisseroth, K.; Akil, H.; Burgess, C. R.; Flagel, S.
10.1101/2023.05.03.539324 — neuroscience — Posted on 2023-05-05
3771 Characterization of the small Arabidopsis thaliana GTPase and ADP-ribosylation factor-like 2 protein TITAN5
Mohr, I.; Mirzaiebadizi, A.; Sanyal, S.; Chuenban, P.; Ahmadian, M. R.; Ivanov, R.; Bauer, P.
10.1101/2023.04.27.538563 — plant biology — Posted on 2023-05-05
3772 Pathogen protein modularity enables elaborate mimicry of a host phosphatase
Li, H.; Wang, J.; Kuan, T.; Tang, B.; Feng, L.; Wang, J.; Cheng, Z.; Sklenar, J.; Derbyshire, P.; Hulin, M.; Li, Y.; Zhai, Y.; Hou, Y.; Menke, F.; Wang, Y.; Ma, W.
10.1101/2023.05.05.539533 — plant biology — Posted on 2023-05-05
3775 Growth Signaling Autonomy in Circulating Tumor Cells Aids Metastatic Seeding
Sinha, S.; Farfel, A.; Luker, K. E.; Parker, B. A.; Yeung, K.; Luker, G. D.; Ghosh, P.
10.1101/2022.12.02.518910 — cancer biology — Posted on 2023-05-05
3780 Biosynthesis of gibberellin-related compounds modulates far-red light responses in the liverwort Marchantia polymorpha
Sun, R.; Okabe, M.; Miyazaki, S.; Ishida, T.; Mashiguchi, K.; Inoue, K.; Yoshitake, Y.; Yamaoka, S.; Nishihama, R.; Kawaide, H.; Nakajima, M.; Yamaguchi, S.; Kohchi, T.
10.1101/2023.05.04.539458 — plant biology — Posted on 2023-05-05
3781 Lack of detection of SARS-CoV-2 in British wildlife 2020-21 and first description of a stoat (Mustela erminea) Minacovirus
Apaa, T.; Withers, A.; McKenzie, L.; Staley, C. E.; Blanchard, A. M.; Bennett, M.; Bremner-Harrison, S.; Chadwick, E.; Hailer, F.; Harrison, S.; Lambin, X.; Loose, M.; Mathews, F.; Tarlinton, R. E.
10.1101/2023.04.28.538769 — microbiology — Posted on 2023-05-05
3782 Post-translational regulation of photosynthetic activity via the TOR kinase in plants.
D'Alessandro, S.; Velay, F.; Lebrun, R.; Mehrez, M.; Romand, S.; Saadouni, R.; Forzani, C.; Citerne, S.; Montane, M.-h.; Robaglia, C.; Menand, B.; Meyer, C.; Field, B.
10.1101/2023.05.05.539554 — plant biology — Posted on 2023-05-05
3784 Functional GPCR expression in eukaryotic LEXSY system
Luginina, A.; Maslov, I.; Khorn, P.; Volkov, O.; Khnykin, A.; Kuzmichev, P.; Shevtsov, M.; Belousov, A.; Dashevskii, D.; Kornilov, D.; Bestsennaia, E.; Hofkens, J.; Hendrix, J.; Gensch, T.; Cherezov, V.; Ivanovich, V.; Mishin, A.; Borshchevskiy, V. I.
10.1101/2023.05.04.539202 — biophysics — Posted on 2023-05-05
3789 Macrophages allocate before apoptosis initiation and produce reactive oxygen species during interdigital phagocytosis
Hernandez-Garcia, D.; Garcia-Melendrez, C.; Hernandez-Martinez, R.; Collazo-Navarrete, O.; Covarrubias, L.
10.1101/2023.05.04.539494 — developmental biology — Posted on 2023-05-04
3791 Histone monoaminylation dynamics are regulated by a single enzyme and promote neural rhythmicity
Zheng, Q.; Bastle, R. M.; Zhao, S.; Kong, L.; Vostal, L.; Ramakrishnan, A.; Shen, L.; Fulton, S. L.; Wang, H.; Zhang, B.; Upad, A.; Thompson, R. E.; Molina, H.; Stransky, S.; Sidoli, S.; Muir, T. W.; Li, H.; David, Y.; Maze, I.
10.1101/2022.12.06.519310 — molecular biology — Posted on 2023-05-04
3792 Graded functional changes in ATL reflect both semantic content and process.
Krieger-Redwood, K.; Wang, X.; Souter, N. E.; Alam, T. R. d. J. G.; Smallwood, J.; Jackson, R.; Jefferies, E.
10.1101/2023.05.04.539459 — neuroscience — Posted on 2023-05-04
3793 Schema cell formation in orbitofrontal cortex is suppressed by hippocampal output
Zong, W.; Zhou, J.; Gardner, M. P. H.; Zhang, Z.; Costa, K. M.; Schoenbaum, G.
10.1101/2023.05.03.539307 — neuroscience — Posted on 2023-05-04
3795 ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex
Fulton, S. L.; Bendl, J.; Gameiro-Ros, I.; Fullard, J. F.; Al-Kachak, A.; Lepack, A. E.; Stewart, A. F.; Singh, S.; Poller, W. C.; Bastle, R. M.; Hauberg, M. E.; Fakira, A. K.; Chen, M.; Durand-de Cuttoli, R.; Cathomas, F.; Ramakrishnan, A.; Gleason, K.; Shen, L.; Tamminga, C. A.; Milosevic, A.; Russo, S. J.; Swirski, F.; Blitzer, R. D.; Slesinger, P. A.; Roussos, P.; Maze, I.
10.1101/2023.05.04.539425 — neuroscience — Posted on 2023-05-04
3796 Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress-induced gene expression and behavior
Al-Kachak, A.; Fulton, S. L.; Farrelly, L. A.; Lepack, A. E.; Bastle, R. M.; Kong, L.; Cathomas, F.; Newman, E. L.; Menard, C.; Ramakrishnan, A.; Chan, J. C.; Safovich, P.; Lyu, Y.; Covington, H. E.; Shen, L.; Gleason, K.; Tamminga, C. A.; Russo, S. J.; Maze, I.
10.1101/2023.05.04.539464 — neuroscience — Posted on 2023-05-04
3799 Single Cell Resolution Spatial Mapping of Human Hematopoiesis Reveals Aging-Associated Topographic Remodeling
Sarachakov, A.; Svekolkin, V.; Varlamova, A.; Galkin, I.; Valencia, I.; Unkenholz, C.; Pannellini, T.; Akaeva, A.; Smirnova, S.; Ovcharov, P.; Polyakova, M.; Tabakov, D.; Postovalova, E.; Sethi, I.; Shin, N.; Bagaev, A.; Itkin, T.; Crane, G.; Kluk, M. J.; Geyer, J.; Inghirami, G.; Patel, S.
10.1101/2023.04.28.538715 — systems biology — Posted on 2023-05-04
3800 KDM4A promotes the progression of neuroendocrine prostate cancer
Mak, C. S. L.; Zhu, M.; Liang, X.; Wang, F.; Yuan, F.; Hoang, A. G.; Song, X.; Shepherd, P.; Liang, D.; Suh, J.; Pradhan, B.; Park, J.; Zhang, M.; Metzger, E.; Schule, R.; Jain, A. K.; Foster, B. A.; Lee, M. G.; Corn, P.; Logothetis, C. J.; Aparicio, A.; Navone, N.; Troncoso, P.; Tan, Z.; Zhang, J.; Lin, S.-H.; Wang, G.
10.1101/2022.05.14.491739 — cancer biology — Posted on 2023-05-04
3801 Passive endocytosis in model protocells
Zhang, S. J.; Lowe, L. A.; Anees, P.; Krishnan, Y.; Fai, T. G.; Szostak, J. W.; Wang, A.
10.1101/2023.01.07.522792 — biophysics — Posted on 2023-05-04
3803 A unified model for the dynamics of ATP-independent ultrafast contraction
Floyd, C.; Molines, A. T.; Lei, X.; Honts, J. E.; Chang, F.; Elting, M. W.; Vaikuntanathan, S.; Dinner, A. R.; Bhamla, M. S.
10.1101/2022.10.14.512304 — biophysics — Posted on 2023-05-04
3805 An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability
Jain, K.; Marunde, M. R.; Burg, J. M.; Gloor, S. L.; Joseph, F. M.; Poncha, K. F.; Gillespie, Z. B.; Rodriguez, K. L.; Popova, I. K.; Hall, N. W.; Vaidya, A.; Howard, S. A.; Taylor, H. F.; Mukhsinova, L.; Onuoha, U. C.; Patteson, E. F.; Cooke, S. W.; Taylor, B. C.; Weinzapfel, E. N.; Cheek, M. A.; Meiners, M. J.; Fox, G. C.; Namitz, K. E. W.; Cowles, M. W.; Krajewski, K.; Sun, Z.-W.; Cosgrove, M. S.; Young, N. L.; Keogh, M.-C.; Strahl, B. D.
10.1101/2022.02.28.482307 — biochemistry — Posted on 2023-05-04
3806 Whole-genome long-read sequencing downsampling and its effect on variant calling precision and recall
Harvey, W. T.; Ebert, P.; Ebler, J.; Audano, P. A.; Munson, K. M.; Hoekzema, K.; Porubsky, D. E.; Beck, C. R.; Marschall, T. R.; Garimella, K. V.; Eichler, E. E.
10.1101/2023.05.04.539448 — genomics — Posted on 2023-05-04
3807 Novel regulatory variant in ABO intronic RUNX1 binding site inducing A3 phenotype
Thun, G. A.; Gueuning, M.; Sigurdardottir, S.; Meyer, E.; Gourri, E.; Schneider, L.; Merki, Y.; Trost, N.; Neuenschwander, K.; Engstroem, C.; Frey, B. M.; Meyer, S.; Mattle-Greminger, M. P.
10.1101/2023.05.04.539366 — genetics — Posted on 2023-05-04
3811 Phosphorylation of 53BP1 by ATM enforce neurodevelopmental programs in cortical organoids
Lim, B.; Djekidel, M. N.; Matsui, Y.; Jun, S.; Yuan, Z.-F.; Wang, X.; Yang, X.; Pilehroud, A. S.; Pan, H.; Wang, F.; Pruett-Miller, S.; Kavidia, K.; Pagala, V.; Fan, Y.; Peng, J.; Xu, B.; Peng, J. C.
10.1101/2023.05.04.539457 — developmental biology — Posted on 2023-05-04
3812 Interplay between PLEKHG3-regulated actin dynamics and lysosomal trafficking in cell motility
Ettelt, R.; Vucak, G.; Didusch, S.; Riemelmoser, B.; Ehrenreiter, K.; Hartl, M.; Huber, L.; Baccarini, M.
10.1101/2023.02.01.526449 — cell biology — Posted on 2023-05-04
3813 Shock drives a highly coordinated transcriptional and DNA methylation response in the endothelium
Ramos, R. B.; Martino, N.; Chuy, D. S.; Lu, S.; Balasubramanian, U.; Di John Portela, I.; Vincent, P. A.; Adam, A. P.
10.1101/2022.08.01.502384 — cell biology — Posted on 2023-05-04
3814 Submitochondrial Protein Translocation Upon Stress Inhibits Thermogenic Energy Expenditure
Haczeyni, F.; Steensels, S.; Stein, B. D.; Jordan, J.; Li, L.; Dartigue, V.; Sarklioglu, S.; Qiao, J.; Zhou, X. K.; Dannenberg, A. J.; Iyengar, N.; Yu, H.; Cantley, L. C.; Ersoy, B. A.
10.1101/2023.05.04.539294 — molecular biology — Posted on 2023-05-04
3816 A parabrachial-hypothalamic parallel circuit governs cold defense in mice
Yang, W. Z.; Xie, H.; Du, X.; Zhou, Q.; Xiao, Y.; Zhao, Z.; Jia, X.; Xu, J.; Zhang, W.; Li, Z.; Fu, X.; Hua, R.; Cai, J.; Chang, S.; Sun, J.; Sun, H.; Xu, Q.; Ni, X.; Tu, H.; Zheng, R.; Xu, X.; Wang, H.; Fu, Y.; Wang, L.; Li, X.; Yang, H.; Yao, Q.; Yu, T.; Shen, Q.; Shen, W. L.
10.1101/2023.04.19.537288 — neuroscience — Posted on 2023-05-04
3817 Large-scale high-density brain-wide neural recording in nonhuman primates
Trautmann, E. M.; Hesse, J. K.; Stine, G. M.; Xia, R.; Shude Zhu, S.; O'Shea, D. J.; Karsh, B.; Colonell, J.; Lanfranchi, F.; Vyas, S.; Zimnik, A.; Steinemann, N. A.; Wagenaar, D. A.; Andrei, A.; Mora Lopez, C.; OCallaghan, J. M.; Putzeys, J.; Raducanu, B. C.; Welkenhuysen, M.; Churchland, M.; Moore, T.; Shadlen, M. N.; Shenoy, K. V.; Tsao, D.; Dutta, B.; Harris, T.
10.1101/2023.02.01.526664 — neuroscience — Posted on 2023-05-04
3818 Ethanol's interaction with BK channel α subunit residue K361 does not mediate behavioral responses to alcohol in mice
Okhuarobo, A.; Kreifeldt, M.; Gandhi, P. J.; Lopez, C.; Martinez, B.; Bajo, M.; Bhattacharyya, P.; Dopico, A. M.; Roberto, M.; Roberts, A. J.; Homanics, G. E.; Contet, C.
10.1101/2020.10.29.360107 — neuroscience — Posted on 2023-05-04
3822 Self-assembly of DNA nanostructures in different cations
Rodriguez, A.; Gandavadi, D.; Mathivanan, J.; Song, T.; Madhanagopal, B. R.; Talbot, H.; Sheng, J.; Wang, X.; Chandrasekaran, A. R.
10.1101/2023.05.04.539416 — synthetic biology — Posted on 2023-05-04
3824 Engineered cytokine/antibody fusion proteins improve delivery of IL-2 to pro-inflammatory cells and promote antitumor activity
Leonard, E. K.; Tomala, J.; Gould, J. R.; Leff, M. I.; Lin, J.-X.; Lin, P.; Porter, M. J.; Johansen, E. R.; Thompson, L.; Cao, S. D.; Henclova, T.; Huliciak, M.; Vanek, O.; Kovar, M.; Leonard, W. J.; Spangler, J. B.
10.1101/2023.05.03.539272 — bioengineering — Posted on 2023-05-04
3825 Visualizing the chaperone-mediated folding trajectory of the G protein β5 β-propeller
Wang, S.; Sass, M. I.; Kwon, Y.; Ludlam, W. G.; Smith, T. M.; Carter, E. J.; Gladden, N. E.; Riggi, M.; Iwasa, J. H.; Willardson, B. M.; Shen, P. S.
10.1101/2023.05.04.539424 — biochemistry — Posted on 2023-05-04
3826 Structural basis and functional roles for Toll-like receptor binding to Latrophilin adhesion-GPCR in embryo development
Rosas, G. C.; Li, J.; Smith, J. J.; Cheng, S.; Baltrusaitis, E.; Nawrocka, W.; Zhao, M.; Kratsios, P.; Arac, D.; Ozkan, E.
10.1101/2023.05.04.539414 — biochemistry — Posted on 2023-05-04
3827 Structural and biochemical characterisation of the N-Carbamoyl-beta-Alanine Amidohydrolases from Rhizobium radiobacter MDC 8606
Paloyan, A.; Sargsyan, A.; Karapetyan, M. D.; Hambardzumyan, A.; Kocharov, S.; Panosyan, H.; Dukova, K. D.; Kinosyan, M.; Krueger, A.; Piergentili, C.; Stanley, W. A.; Basle, A.; Antranikian, G.; Marles-Wright, J.
10.1101/2023.05.04.538398 — biochemistry — Posted on 2023-05-04
3828 Long-read sequencing and profiling of RNA-binding proteins reveals the pathogenic mechanism of aberrant splicing of an SCN1A poison exon in epilepsy
Happ, H. C.; Schneider, P. N.; Hong, J. H.; Goes, E.; Bandouil, M.; Biar, C. G.; Ramamurthy, A.; Reese, F.; Engel, K.; Weckhuysen, S.; Scheffer, I. E.; Mefford, H. C.; Calhoun, J. D.; Carvill, G. L.
10.1101/2023.05.04.538282 — genetics — Posted on 2023-05-04
3830 TLR priming licenses NAIP inflammasome activation by immunoevasive ligands
Grayczyk, J. P.; Egan, M. S.; Liu, L.; Aunins, E.; Wynosky-Dolfi, M. A.; Canna, S.; Minn, A. J.; Shin, S.; Brodsky, I. E.
10.1101/2023.05.04.539437 — molecular biology — Posted on 2023-05-04
3831 Draft genome sequence of Microbacterium fakhimi sp. nov., a novel bacterium associated with the alga Chlamydomonas reinhardtii
Fakhimi, N.; Torres, M. J.; Delgado-Luque, J.; Fernandez, E.; Galvan, A.; Dubini, A.; Gonzalez-Ballester, D.
10.1101/2023.05.04.539371 — microbiology — Posted on 2023-05-04
3834 Structural and functional characterization of the NF-κB-targeting toxin AIP56 from Photobacterium damselae subsp. piscicida reveals a novel mechanism for membrane interaction and translocation
Lisboa, J.; Pereira, C.; Pinto, R. D.; Rodrigues, I. S.; Pereira, L. M. G.; Pinheiro, B.; Oliveira, P.; Pereira, P. J. B.; Azevedo, J. E.; Durand, D.; Benz, R.; Vale, A. d.; dos Santos, N. M. S.
10.1101/2023.05.04.539443 — microbiology — Posted on 2023-05-04
3835 Intercellular interaction between FAP fibroblasts and CD150 inflammatory monocytes mediates fibro-stenosis in Crohn's disease
Ke, B.-J.; Abdurahiman, S.; Biscu, F.; Dragoni, G.; Santhosh, S.; De Simone, V.; Zouzaf, A.; van Baarle, L.; Stakenborg, M.; Bosakova, V.; Van Rymenant, Y.; Verhulst, E.; Verstockt, S.; Bislenghi, G.; Wolthuis, A.; Fric, J.; Breynaert, C.; D'Hoore, A.; Van Der Veken, P.; De Meester, I.; Verstockt, B.; de Hertogh, G.; Vermeire, S.; Matteoli, G.
10.1101/2023.05.04.539383 — immunology — Posted on 2023-05-04
3839 CTCF-mediated insulation and chromatin environment modulate Car5b escape from X inactivation
Fang, H.; Tronco, A. R.; Bonora, G.; Nguyen, T.; Thakur, J.; Berletch, J. B.; Filippova, G. N.; Henikoff, S.; Shendure, J.; Noble, W. S.; Disteche, C. M.; Deng, X.
10.1101/2023.05.04.539469 — genomics — Posted on 2023-05-04
3840 The microbiota of Amblyomma americanum reflects known westward expansion.
Villegas, L. E. M.; Lado, P.; Klompen, H.; Wang, S.; Cummings, C.; Pesapane, R.; Short, S. M.
10.1101/2023.05.04.539455 — ecology — Posted on 2023-05-04
3842 Human Smc5/6 recognises transcription-generated positive DNA supercoils
Diman, A.; Panis, G.; Castrogiovanni, C.; Prados, J.; Baechler, B.; Strubin, M.
10.1101/2023.05.04.539344 — molecular biology — Posted on 2023-05-04
3843 Pulmonary Matrix Derived Hydrogels from Patients with Idiopathic Pulmonary Fibrosis Induce a Proinflammatory State in Lung Fibroblasts In Vitro
Fernandez Davila, J. G.; Moore, D. W.; Kim, J.; Khan, J. A.; Singh, A. K.; Lemma, M.; King, C. S.; Nathan, S. D.; Rodriguez, L. R.; Grant, G. M.; Moran, J. L.
10.1101/2023.05.03.539323 — molecular biology — Posted on 2023-05-04
3844 A bivalent ChAd nasal vaccine protects against SARS-CoV-2 BQ.1.1 and XBB.1.5 infection and disease in mice and hamsters
Ying, B.; Darling, T. L.; Desai, P.; Liang, C.-Y.; Dmitriev, I. P.; Soudani, N.; Bricker, T. L.; Kashentseva, E. A.; Harastani, H. H.; Schmidt, A. G.; Curiel, D. T.; Boon, A. C. M.; Diamond, M. S.
10.1101/2023.05.04.539332 — microbiology — Posted on 2023-05-04
3848 Broad-Spectrum Heavily Mutated Monoclonal Antibody Isolated from COVID-19 Convalescent Vaccinee with Capacity to Neutralize SARS-CoV2 Variants Ranging from B.1 to BQ.1.1
Choudhary, A. K.; Calianese, D.; Honnen, W.; Kolloli, A.; Dikdan, R. J.; Jaijyan, D.; Song, G.; Capozzola, T.; Akkaraju, V.; Mattappallil, A.; Rosania, A.; Khan, S.; Lerman, M.; Afzal, N.; Subbian, S.; Chou, T. C.; Andrabi, R.; Burton, D.; Pinter, A.
10.1101/2023.05.04.539267 — immunology — Posted on 2023-05-04
3849 EXTRANEURAL RABIES VIRUS INFECTION LEADS TO TISSUE DAMAGE AND CELL DEATH IN MICE
Leal Rodrigues, E. D.; Pacheco da Silva, V.; Bastos Chaves, V. G.; de Sousa Moraes, C. N.; de Souza Pereira, S.; Nogueira Lima, A. L.; Fernandes Barbosa Coelho, T.; da Costa Vasconcelos, P. F.; Ribeiro Cruz, A. C.; Medeiros Neves Casseb, L.
10.1101/2023.05.04.539354 — immunology — Posted on 2023-05-04
3850 Destabilization of neuromuscular junctions and deregulation of activity-dependent signalling pathways in Myotonic Dystrophy type I
Falcetta, D.; Quirim, S.; Cocchiararo, I.; Cornut, M.; Theodore, M.; Stiefvater, A.; Lin, S.; Tintignac, L.; Ivanek, R.; Kinter, J.; Ruegg, M. A.; Sinnreich, M.; Castets, P.
10.1101/2023.03.08.531688 — physiology — Posted on 2023-05-04
3853 Structure of the N-terminal didomain d1_d2 of the Thrombospondin type-1 domain-containing 7A
Bochel, A.; Mortensen, S. A.; Seifert, L.; Hengel, F. E.; Jeffries, C. M.; Chojnowski, G.; Kretz, O.; Huber, T. B.; Tomas, N. M.; Wilmanns, M.
10.1101/2023.05.03.539264 — biophysics — Posted on 2023-05-04
3855 Enhancing drug repurposing on graphs by integrating drug molecular structure as feature
Ayuso-Munoz, A.; Prieto-Santamaria, L.; Alvarez-Perez, A.; Otero-Carrasco, B.; Serrano, E.; Rodriguez-Gonzalez, A.
10.1101/2023.05.03.539227 — bioinformatics — Posted on 2023-05-04
3857 Non-cell-adhesive hydrogel promotes formation of human blastoid from primed human pluripotent stem cells.
Imamura, S.; Wen, X.; Terada, S.; Yamamoto, A.; Mutsuda-Zapater, K.; Sawada, K.; Yoshimoto, K.; Tanaka, M.; Kamei, K.-i.
10.1101/2022.06.23.497328 — bioengineering — Posted on 2023-05-04
3858 Multiplexed fluorescence and scatter detection with single cell resolution using on-chip fiber optics for droplet microfluidic applications
Gupta, P.; Mohan, A.; Mishra, A.; Nair, A.; Chowdhury, N.; Balekai, D.; Rai, K.; Mehta, P.; Prabhakar, A.; Saiyed, T.
10.1101/2023.05.03.539123 — bioengineering — Posted on 2023-05-04
3861 Direct quantification of chemogenetic H2O2 production in live human cells.
den Toom, W. T. F.; van Soest, D. M. K.; Polderman, P. E.; van Triest, M. H.; Bruurs, L. J. M.; Burgering, B. M. T.; De Henau, S.; Dansen, T. B.
10.1101/2023.05.03.539306 — cell biology — Posted on 2023-05-04
3862 Ornithodoros maritimus as a vector of Babesia sp. YLG in Yellow-legged gull (Larus michahellis) nests
Bonsergent, C.; Vittecoq, M.; Leray, C.; Jouglin, M.; Buysse, M.; McCoy, K.; Malandrin, L.
10.1101/2023.03.24.534071 — microbiology — Posted on 2023-05-04
3864 The glucocorticoid dexamethasone impairs the expression of anti-viral mediators in activated macrophages by inhibiting both expression and function of interferon beta.
O'Neil, J. D.; Bolimowska, O. O.; Clayton, S. A.; Tang, T.; Daley, K. K.; Lara-Reyna, S.; Warner, J.; Martin, C. S.; Mahida, R. Y.; Hardy, R. S.; Arthur, S.; Clark, A. R.
10.1101/2023.05.03.539212 — immunology — Posted on 2023-05-04
3867 Genome assembly and analysis of Lactuca virosa: implications for lettuce breeding
Xiong, W.; van Workum, D.-J. M.; Berke, L.; Bakker, L. V.; Schijlen, E.; Becker, F. F. M. F. M.; van de Geest, H.; Peters, S.; Michelmore, R.; van Treuren, R.; Jeuken, M. J. W.; Smit, S.; Schranz, M. E.
10.1101/2023.05.03.539295 — plant biology — Posted on 2023-05-04
3868 A time-resolved meta-analysis of consensus gene expression profiles during human T-cell activation
Rade, M.; Boehlen, S.; Neuhaus, V.; Loeffler, D.; Blumert, C.; Koehl, U.; Dehmel, S.; Sewald, K.; Reiche, K.
10.1101/2023.05.03.538418 — bioinformatics — Posted on 2023-05-04
3869 Reverse Engineering DNA Origami Nanostructure Designs from Raw Scaffold and Staple Sequence Lists
Shirt-Ediss, B.; Connolly, J.; Elezgaray, J.; Torelli, E.; Navarro, S. A.; Bacardit, J.; Krasnogor, N.
10.1101/2023.05.03.539261 — bioinformatics — Posted on 2023-05-04
3870 Engineered cytokine/antibody fusion proteins improve delivery of IL-2 to pro-inflammatory cells and promote antitumor activity
Leonard, E. K.; Tomala, J.; Leff, M. I.; Lin, J.-X.; Lin, P.; Porter, M. J.; Johansen, E. R.; Thompson, L.; Cao, S. D.; Henclova, T.; Huliciak, M.; Vanek, O.; Kovar, M.; Leonard, W. J.; Spangler, J. B.
10.1101/2023.05.03.539272 — bioengineering — Posted on 2023-05-04
3872 Scalable Mesenchymal Stem Cells Enrichment from Bone Marrow Aspirate using Deterministic Lateral Displacement (DLD) Microfluidics Sorting
Tan, N.; Kwek, K. Z.; Teo, K. L.; Loberas, M.; Lee, J. L.; Goh, C. R.; Yang, D.; Oh, S.; Hui, J.; Cool, S.; Wei Hou, H.; Han, J.
10.1101/2023.05.03.539013 — bioengineering — Posted on 2023-05-04
3877 Mechanical Dissociation of Tissues for Single Cell Analysis Using a Simple Motorized Device
Amosu, M.; Gregory, A. J.; Murtagh, J. D.; Pavin, N.; Meyers, C. T.; Grano de Oro Fernandez, J.; Moore, K.; Maisel, K.
10.1101/2023.05.03.539271 — cell biology — Posted on 2023-05-04
3879 K29-linked unanchored polyubiquitin chains disrupt ribosome biogenesis and direct ribosomal proteins to the Intranuclear Quality control compartment (INQ)
Garadi Suresh, H.; Bonneil, E.; Albert, B.; Dominique, C.; Costanzo, M.; Pons, C.; Masinas, M. P. D.; Shuteriqi, E.; Shore, D.; Henras, A. K.; Thibault, P.; Boone, C.; Andrews, B. J.
10.1101/2023.05.03.539259 — cell biology — Posted on 2023-05-04
3881 A novel subset of colonocytes targeted by Citrobacter rodentium elicits epithelial MHCII-restricted help from CD4 T cells
Zindl, C.; Wilson, C. G.; Chadha, A.; Cai, B.; Harbour, S.; Nagaoka-Kamata, Y.; Hatton, R.; Gao, M.; Figge, D.; Weaver, C.
10.1101/2023.05.03.539269 — immunology — Posted on 2023-05-04
3886 CAF variants control the tumor-immune microenvironment and predict skin cancer malignancy
Forsthuber, A.; Korosec, A.; Jacob, T.; Aschenbrenner, B.; Annusver, K.; Frech, S.; Purkhauser, K.; Krajic, N.; Lipp, K.; Werner, F.; Nguyen, V.; Griss, J.; Bauer, W.; Cardona, A. S.; Weber, B.; Weninger, W.; Gesslbauer, B.; Staud, C.; Nedomansky, J.; Radtke, C.; Wagner, S. N.; Petzelbauer, P.; Kasper, M.; Lichtenberger, B. M.
10.1101/2023.05.03.539213 — cancer biology — Posted on 2023-05-04
3888 Connexin 43 mediated collective cell migration is independent of Golgi orientation
Sharma, M.; Mukherjee, S.; Shaw, A. K.; Mondal, A.; Behera, A.; Das, J.; Bose, A.; Sinha, B.; DasSarma, J.
10.1101/2023.05.03.539214 — biophysics — Posted on 2023-05-04
3894 cellsnake: a user-friendly tool for single cell RNA sequencing analysis
Umu, S. U.; Rapp Vander-Elst, K.; Karlsen, V. T.; Chouliara, M.; Baekkevold, E. S.; Jahnsen, F. L.; Domanska, D.
10.1101/2023.05.03.539204 — bioinformatics — Posted on 2023-05-04
3895 HiPhase: Jointly phasing small and structural variants from HiFi sequencing
Holt, J. M.; Saunders, C. T.; Rowell, W. J.; Kronenberg, Z.; Wenger, A. M.; Eberle, M.
10.1101/2023.05.03.539241 — bioinformatics — Posted on 2023-05-04
3897 Extreme mitochondrial reduction in a novel group of free-living metamonads.
Williams, S. K.; Jerlstom-Hultqvist, J.; Eglit, Y.; Salas-Leiva, D. E.; Curtis, B.; Orr, R. J. S.; Stairs, C. W.; Simpson, A. G. B.; Roger, A. J.
10.1101/2023.05.03.539051 — genomics — Posted on 2023-05-04
3899 Generation of a human Tropomyosin 1 knockout iPSC line
Wilken, M. B.; Maguire, J. A.; Dungan, L. V.; Gagne, A.; Osorio-Quintero, C.; Waxman, E. A.; Chou, S. T.; Gadue, P.; French, D. L.; Thom, C. S.
10.1101/2023.05.03.539242 — cell biology — Posted on 2023-05-04
3901 Engineering of a biosensor for intracellular aspartate
Hellweg, L.; Pfeifer, M.; Chang, L.; Tarnawski, M.; Bergner, A.; Kress, J.; Hiblot, J.; Reinhardt, J.; Johnsson, K.; Leippe, P.
10.1101/2023.05.04.537313 — cell biology — Posted on 2023-05-04
3902 Composition of nasopharyngeal microbiota in individuals with SARS-CoV-2 infection across three COVID-19 waves in India
Bose, T.; Wasimuddin, ; Acharya, V.; Pinna, N. K.; Kaur, H.; Ranjan, M.; Jandhyala, S.; Nagabandi, T.; Varma, B.; Tallapaka, K. B.; Sowpati, D. T.; Haque, M. M.; Dutta, A.; Siva, A. B.; Mande, S. S.
10.1101/2023.01.02.522449 — microbiology — Posted on 2023-05-04
3905 Shared requirement for MYC upstream super-enhancer region in tissue regeneration and cancer
Sur, I. K.; Zhao, W.; Zhang, J.; Kling Pilstrom, M.; Rozell, B.; Webb, A.; Cheng, H.; Ristimaki, A.; Katajisto, P.; Enge, M.; Rannikmae, H.; de la Roche, M. A.; Taipale, J.
10.1101/2022.11.04.515076 — cancer biology — Posted on 2023-05-04
3906 Sexual differentiation of neural mechanisms of stress sensitivity during puberty
Wright, E. C.; Zakharenkov, H. C.; Godoy, A. S.; Lake, A. A.; Prince, Z. D.; Sekar, S.; Culkin, H. I.; Luo, P. X.; Ramirez, A. V.; Dwyer, T.; Kapoor, A.; Corbett, C.; Tian, L.; Fox, A. S.; Trainor, B. C.
10.1101/2020.12.02.408526 — neuroscience — Posted on 2023-05-04
3907 Compensatory mechanisms upon Gata2b haploinsufficiency cause aberrant transcriptional regulatory signatures in HSPCs resulting in myeloid and erythroid dysplasia in zebrafish
Gioacchino, E.; Zhang, W.; Koyunlar, C.; Zink, J.; de Looper, H.; Gussinklo, K. J.; Hoogenboezem, R.; Bosch, D.; Bindels, E.; Touw, I. P.; de Pater, E.
10.1101/2021.10.29.466416 — cancer biology — Posted on 2023-05-04
3912 ARID1B controls transcriptional programs of axon projection in the human corpus callosum
Martins-Costa, C.; Pham, V. A.; Wiegers, A.; Sidhaye, J.; Doleschall, B.; Novatchkova, M.; Lendl, T.; Piber, M.; Peer, A.; Moeseneder, P.; Stuempflen, M.; Chow, S. Y. A.; Seidl, R.; Prayer, D.; Hoeftberger, R.; Kasprian, G.; Ikeuchi, Y.; Corsini, N.; Knoblich, J. A.
10.1101/2023.05.04.539362 — neuroscience — Posted on 2023-05-04
3914 Vibrio cholerae's ToxRS Bile Sensing System
Gubensaek, N.; Sagmeister, T.; Buhlheller, C.; Geronimo, B. D.; Wagner, G. E.; Petrowitsch, L.; Graewert, M. A.; Rotzinger, M.; Berger, T. I.; Schäfer, J.; Uson, I.; Reidl, J.; Sanchez-Murcia, P. A.; Zangger, K.; Pavkov-Keller, T.
10.1101/2023.05.02.539094 — biochemistry — Posted on 2023-05-04
3915 Genomic screening of 16 UK native bat species through conservationist networks uncovers coronaviruses with zoonotic potential
Tan, C.; Trew, J.; Peacock, T. P.; Mok, K.; Hart, C.; Lau, K.; Ni, D.; Orme, D.; Ransome, E.; Pearse, W.; Coleman, C.; Bailey, D.; Thakur, N.; Quantrill, J.; Sukhova, K.; Richard, D.; Kahane, L.; Woodward, G.; Bell, T.; Worledge, L.; Nunez-Mino, J.; Barclay, W. S.; van Dorp, L.; Balloux, F.; Savolainen, V.
10.1101/2023.01.17.524183 — genomics — Posted on 2023-05-04
3918 Proteasome gene expression is controlled by the coordinated functions of multiple transcription factors
Gilda, J. E.; Nahar, A.; Kasiviswanathan, D.; Tropp, N.; Gilinski, T.; Lahav, T.; Mandel-Gutfreund, Y.; Park, S.; Cohen, S.
10.1101/2023.04.12.536627 — cell biology — Posted on 2023-05-04
3925 β-ionone regulates Arabidopsis thaliana transcriptome and increases its resistance against Botrytis cinerea
Felemban, A.; Moreno Beltran, J. C.; Mi, J.; Ali, S.; Sham, A.; AbuQamar, S. F.; Al-Babili, S.
10.1101/2023.05.02.539130 — plant biology — Posted on 2023-05-04
3926 Exercise Mitigates Flow Recirculation and Activates Mechanosensitive Transcriptome to Uncover Endothelial SCD1-Catalyzed Anti-Inflammatory Metabolites
Cavallero, S.; Roustaei, M.; Satta, S.; Cho, J. M.; Phan, H.; Baek, K. I.; Blazquez-Medela, A. M.; Gonzalez-Ramos, S.; Vu, K.; Park, S.-K.; Yokota, T.; Sumner, J. A.; Mack, J.; Sigmund, C. D.; Reddy, S.; Li, R.; Hsiai, T. K.
10.1101/2023.05.02.539172 — physiology — Posted on 2023-05-04
3927 The D84G mutation in STIM1 causes nuclear envelope dysfunction and myopathy in mice
Bryson, V.; Wang, C.; Zhou, Z. A.; Singh, K.; Volin, N.; Yildirim, E.; Rosenberg, P.
10.1101/2023.05.03.539279 — physiology — Posted on 2023-05-04
3929 Label-free and high-throughput removal of residual undifferentiated cells from iPSC-derived spinal-cord progenitor cells
Nguyen, T. D.; Chooi, W. H.; Jeon, H.; Chen, J.; Roxby, D. N.; Tan, J.; Yi-Pin Lee, C.; Ng, S.-Y.; Chew, S. Y.; Han, J.
10.1101/2022.12.16.520699 — bioengineering — Posted on 2023-05-04
3930 Activation and substrate specificity of the human P4-ATPase ATP8B1
Dieudonne, T.; Kummerer, F.; Juknaviciute Laursen, M.; Stock, C.; Kock Flygaard, R.; Khalid, S.; Lenoir, G.; Lyons, J. A.; Lindorff-Larsen, K.; Nissen, P.
10.1101/2023.04.12.536557 — biochemistry — Posted on 2023-05-04
3931 Interplay between pollution and avian influenza virus infection risk in shorebirds and waterfowl
Ross, T. A.; Zhang, J.; Wille, M.; Asimakopoulos, A. G.; Jaspers, V.; Klaassen, M.
10.1101/2023.02.23.529812 — ecology — Posted on 2023-05-04
3932 Assessment of contaminants, health and survival of migratory shorebirds in natural versus artificial wetlands - the potential of wastewater treatment plants as alternative habitats
Ross, T.; Zhang, J.; Wille, M.; Ciesielski, T. M.; Asimakopoulos, A. G.; Lemesle, P.; Skaalvik, T. G.; Atkinson, R.; Jessop, R.; Victorian Wader Study Group, ; Jaspers, V. L. B.; Klaassen, M.
10.1101/2023.02.15.528752 — ecology — Posted on 2023-05-04
3933 Role of SARS-CoV-2 mutations in the evolution of the COVID-19 pandemic
Colson, P.; Chaudet, H.; Delerce, J.; Pontarotti, P.; Levasseur, A.; Fantini, J.; La Scola, B.; Devaux, C. A.; Raoult, D.
10.1101/2023.05.01.538506 — microbiology — Posted on 2023-05-04
3939 Schema cell formation in orbitofrontal cortex is suppressed by hippocampal output
Zong, W.; Zhou, J.; Gardner, M. P. H.; Costa, K. M.; Zhang, Z.; Schoenbaum, G.
10.1101/2023.05.03.539307 — neuroscience — Posted on 2023-05-03
3944 Mechanism and evolutionary origins of Alanine-tail C-degron recognition by E3 ligases Pirh2 and CRL2-KLHDC10
Patil, P. R.; Burroughs, A. M.; Misra, M.; Cerullo, F.; Dikic, I.; Aravind, L.; Joazeiro, C. A. P.
10.1101/2023.05.03.539038 — molecular biology — Posted on 2023-05-03
3948 The soluble guanylyl cyclase pathway is inhibited to evade androgen deprivation-induced senescence and enable progression to castration resistance
Rai, P.; Zhang, L.; Troccoli, C. I.; Mateo-Victoriano, B.; Misiara, L.; Jackson, E. N.; Shu, P.; Plastini, T. M.; Tao, W.; Kwon, D.; Chen, X.; Sharma, J.; Jorda, M.; Gulley, J. L.; Bilusic, M.; Lockhart, A. C.; Beuve, A.
10.1101/2023.05.03.537252 — cancer biology — Posted on 2023-05-03
3951 Natural and engineered isoforms of the inflammasome adaptor ASC form non-covalent, pH-responsive hydrogels
Gaspar-Morales, E. A.; Waterston, A.; Diaz-Parga, P.; Smith, A. M.; Sadqi, M.; Gopinath, A.; Andresen Eguiluz, R. C.; de Alba, E.
10.1101/2023.05.03.539154 — bioengineering — Posted on 2023-05-03
3954 Role of the inner membrane cytochrome ImcH in Geobacter extracellular electron transfer and energy conservation
Duarte, A. G.; Pereira, I. A. C.; Salgueiro, C. A.; Edwardas, M. J.; Clarke, T. A.; Morgado, L.; Paquete, C. M.; Pimenta, A. I.
10.1101/2023.05.03.539133 — biochemistry — Posted on 2023-05-03
3957 Common Analysis of Direct RNA SequencinG CUrrently Leads to Misidentification of 5-Methylcytosine Modifications at GCU Motifs
Watson, K.; Bromley, R.; Sparklin, B. C.; Gasser, M.; Bhattacharya, T.; Lebov, J. F.; Tyson, T.; Teigen, L.; Graf, K. T.; Michalski, M.; Bruno, V. M.; Lindsey, A. R. I.; Hardy, R. W.; Newton, I. L. G.; Dunning Hotopp, J. C.
10.1101/2023.05.03.539298 — genomics — Posted on 2023-05-03
3958 Cross-feeding affects the target of resistance evolution to an antifungal drug
Durand, R.; Jalbert-Ross, J.; Fijarczyk, A.; Dube, A. K.; Landry, C. R.
10.1101/2023.05.03.539243 — genomics — Posted on 2023-05-03
3959 MSH2 stimulates interfering and inhibits non-interfering crossovers in response to genetic polymorphism
Dluzewska, J.; Dziegielewski, W.; Szymanska-Lejman, M.; Gazecka, M.; Henderson, I. R.; Higgins, J. D.; Ziolkowski, P. A.
10.1101/2023.05.03.539183 — genetics — Posted on 2023-05-03
3960 Populating a Continent: Phylogenomics Reveal the Timing of Australian Frog Diversification
Brennan, I. G.; Lemmon, A. R.; Lemmon, E.; Hoskin, C. J.; Donnellan, S. C.; Keogh, J. S.
10.1101/2023.05.03.539251 — evolutionary biology — Posted on 2023-05-03
3961 Cities as parasitic burden? Malaria prevalence and diversity along an urbanization gradient in great tits
Caizergues, A. E.; Robira, B.; Perrier, C.; Jeanneau, M.; Berthomieu, A.; Perret, S.; Gandon, S.; Charmantier, A.
10.1101/2023.05.03.539263 — ecology — Posted on 2023-05-03
3962 Drosophila FMRP recruits the miRISC to target mRNAs to repress translation
Kaul, N.; Pradhan, S. J.; Boin, N. G.; Mason, M. M.; Rosales, J.; Starke, E. L.; Wilkinson, E. C.; Chapman, E. G.; Barbee, S. A.
10.1101/2023.05.03.539280 — molecular biology — Posted on 2023-05-03
3964 Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis
Min, K.; Yenilmez, B.; Kelly, M.; Echeverria, D.; Elleby, M.; Lifshitz, L. M.; Raymond, N.; Tsagkaraki, E.; Harney, S. M.; DiMarzio, C.; McHugh, N.; Bramato, B.; Morrison, B.; Rothstein, J. D.; Khvorova, A.; Czech, M. P.
10.1101/2023.05.03.539244 — molecular biology — Posted on 2023-05-03
3971 Structure of the N-terminal didomain d1_d2 of the Thrombospondin type-1 domain-containing 7A
Bochel, A.; Mortensen, S. A.; Seifert, L.; Hengel, F. E.; Jeffries, C. M.; Chojnowski, G.; Kretz, O.; Huber, T. B.; Tomas, N. M.; Wilmanns, M.
10.1101/2023.05.03.539264 — biophysics — Posted on 2023-05-03
3974 Variability and Bias in Microbiome Metagenomic Sequencing: an Interlaboratory Study Comparing Experimental Protocols
Forry, S. P.; Servetas, S. L.; Kralj, J. G.; Soh, K.; Hadjithomas, M.; Cano, R.; Carlin, M.; de Amorim, M. G.; Auch, B.; Bakker, M. G.; Bartelli, T. F.; Bustamante, J. P.; Cassol, I.; Chalita, M.; Dias-Neto, E.; Duca, A. D.; Gohl, D.; Haruna, M. T.; Kazantseva, J.; Menzel, P.; Moda, B. S.; Neuberger-Castillo, L.; Nunes, D.; Patel, I. R.; Peralta, R. D.; Saliou, A.; Schwarzer, R.; Sevilla, S.; Takenaka, I. K. T. M.; Wang, J.; Knight, R.; Gevers, D.; Jackson, S. A.
10.1101/2023.04.28.538741 — microbiology — Posted on 2023-05-03
3975 Emergence and suppressive function of Tr1 cells in glomerulonephritis
Soukou-Wargalla, S.; Kilian, C.; Velasquez, L.; Machicote, A.; Stumme, F.; Bedke, T.; Giannou, A.; Kempski, J.; Sabihi, M.; Song, N.; Paust, H.-J.; Borchers, A.; Perez, L. G.; Pelczar, P.; Liu, B.; Ergen, C.; Steglich, B.; Muscate, F.; Huber, T. B.; Panzer, U.; Gagliani, N.; Krebs, C. F.; Huber, S.
10.1101/2023.02.07.527417 — immunology — Posted on 2023-05-03
3976 Origins of proprioceptor feature selectivity and topographic maps in the Drosophila leg
Mamiya, A.; Sustar, A.; Siwanowicz, I.; Qi, Y.; Lu, T.-C.; Gurung, P.; Chen, C.; Phelps, J. S.; Kuan, A. T.; Pacureanu, A.; Lee, W.-C. A.; Li, H.; Mhatre, N.; Tuthill, J. C.
10.1101/2022.08.08.503192 — neuroscience — Posted on 2023-05-03
3978 Spatiotemporal regulation of GIPR signaling impacts glucose homeostasis as revealed in studies of a common GIPR variant.
Yammine, L.; Picatoste, B.; Abdullah, N.; Leahey, R.; Gomez-Banoy, N.; Rosselot, C.; Wen, J.; Goncalves, M. D.; Lo, J. C.; Garcia-Ocana, A.; McGraw, T. E.
10.1101/2020.05.12.091025 — physiology — Posted on 2023-05-03
3979 Disseminating cells in human tumours acquire an EMT cancer stem cell state that is predictive of metastasis
Youssef, G.; Gammon, L.; Ambler, L.; Lunetto, S.; Scemama, A.; Cottom, H.; Piper, K.; Mackenzie, I. C.; Philpott, M. P.; Biddle, A.
10.1101/2020.04.07.029009 — cancer biology — Posted on 2023-05-03
3981 Creating an Ignorance-Base: Exploring Known Unknowns in the Scientific Literature
Boguslav, M. R.; Salem, N. M.; White, E. K.; Sullivan, K. J.; Araki, S. P.; Bada, M.; Hernandez, T. L.; Leach, S. M.; Hunter, L. E.
10.1101/2022.12.08.519634 — bioinformatics — Posted on 2023-05-03
3983 Tyramine and its AmTYR1 receptor modulate attention in honey bees (Apis mellifera)
Latshaw, J. S.; Mazade, R. E.; Petersen, M.; Mustard, J. A.; Sinakevitch, I.; Wissler, L.; Guo, X.; Cook, C. N.; Lei, H.; Gadau, J.; Smith, B. H.
10.1101/2022.09.02.506392 — animal behavior and cognition — Posted on 2023-05-03
3985 Chimeric Antigen Receptor Macrophages Target and Resorb Amyloid Plaques in a Mouse Model of Alzheimer's Disease
Pan, Q.; Yan, P.; Kim, A. B.; Xiao, Q.; Pandey, G.; Haecker, H.; Epelman, S.; Diwan, A.; Lee, J.-M.; DeSelm, C. J.
10.1101/2023.04.28.538637 — immunology — Posted on 2023-05-03
3987 Kappa Opioid Receptor Antagonism Rescues Genetic Perturbation of Dopamine Homeostasis: Molecular, Physiological and Behavioral Consequences
Mayer, F. P.; Stewart, A.; Varman, D. R.; Moritz, A. E.; Foster, J. D.; Owens, A. W.; Areal, L. B.; Gowrishankar, R.; Velez, M.; Wickham, K.; Phelps, H.; Katamish, R.; Rabil, M. J.; Jayanthi, L. D.; Vaughan, R. A.; Daws, L. C.; Blakely, R.; Ramamoorthy, S.
10.1101/2023.05.03.539310 — neuroscience — Posted on 2023-05-03
3988 BIBSNet: A Deep Learning Baby Image Brain Segmentation Network for MRI Scans
Hendrickson, T. J.; Reiners, P.; Moore, L. A.; Perrone, A. J.; Alexopoulos, D.; Lee, E. G.; Styner, M.; Kardan, O.; Chamberlain, T. A.; Mummaneni, A.; Caldas, H. A.; Bower, B.; Stoyell, S.; Martin, T.; Sung, S.; Fair, E.; Uriarte-Lopez, J.; Rueter, A. R.; Yacoub, E.; Rosenberg, M. D.; Smyser, C. D.; Elison, J. T.; Graham, A.; Fair, D. A.; Feczko, E.
10.1101/2023.03.22.533696 — neuroscience — Posted on 2023-05-03
3990 Parallel genome-scale CRISPR screens distinguish pluripotency and self-renewal
Rosen, B. P.; Li, Q. V.; Cho, H.; Liu, D.; Yang, D.; Graff, S.; Yan, J.; Luo, R.; Verma, N.; Damodaran, J. R.; Beer, M. A.; Sidoli, S.; Huangfu, D.
10.1101/2023.05.03.539283 — developmental biology — Posted on 2023-05-03
3993 Inverse blebs operate as hydraulic pumps during mouse blastocyst formation
Schliffka, M. F.; Dumortier, J. G.; Pelzer, D.; Mukherjee, A.; Maitre, J.-L.
10.1101/2023.05.03.539105 — developmental biology — Posted on 2023-05-03
3994 Establishment of a CPER Reverse Genetics System for Powassan Virus Defines Attenuating NS1 Glycosylation Sites and an Infectious NS1-GFP11 Reporter Virus
Conde, J. N.; Himmler, G. E.; Mladinich, M. C.; Setoh, Y. X.; Amarilla, A. A.; Schutt, W. R.; Saladino, N.; Gorbunova, E. E.; Salamango, D. J.; Wimmer, E.; Kim, H. K.; Mackow, E. R.
10.1101/2023.05.03.539311 — microbiology — Posted on 2023-05-03
3995 Identification of the conserved iol gene cluster involved in rhizosphere competence in Pseudomonas
Sanchez-Gil, J. J.; Poppeliers, S. W. M.; Vacheron, J. J.; Zhang, H.; Odijk, B. S.; Keel, C.; de Jonge, R.
10.1101/2023.05.03.538910 — microbiology — Posted on 2023-05-03
4003 Ribosomal protein L24 modulates mammalian microRNA processing and transfer RNA fragment production
Tzur, Y.; Dubnov, S.; Madrer, N.; Bar, A.; Nadorp, B.; Mishra, N.; Heppenstall, P. A.; Bennett, E. R.; Greenberg, D. S.; Winek, K.; Soreq, H.
10.1101/2023.05.03.539194 — molecular biology — Posted on 2023-05-03
4005 Plant inositol transport influences bacterial colonization phenotypes
O'Banion, B. S.; Jones, P.; Demetros, A. A.; Kelley, B. R.; Wagner, A. S.; Chen, J.-G.; Muchero, W.; Reynolds, T. B.; Jacobson, D.; Lebeis, S. L.
10.1101/2023.05.03.538913 — microbiology — Posted on 2023-05-03
4008 An elastic proteinaceous envelope encapsulates the early Arabidopsis embryo
Harnvanichvech, Y.; Borassi, C.; Daghma, D.; van der Kooij, H.; Sprakel, J.; Weijers, D.
10.1101/2023.05.03.539186 — plant biology — Posted on 2023-05-03
4014 Single-cell mutation rate of turnip crinkle virus (-)-strand replication intermediates
Carvalho, C. P.; Han, J.; Khemson, K.; Ren, R.; Camargo, L. E. A.; Miyashita, S.; Qu, F.
10.1101/2023.05.03.539190 — evolutionary biology — Posted on 2023-05-03
4015 Cognitive outcome and its neural correlates after cardiorespiratory arrest in childhood
Geva, S.; Hoskote, A.; Saini, M.; Clark, C. A.; Banks, T.; Chong, K. W. K.; Baldeweg, T.; de Haan, M.; Vargha-Khadem, F.
10.1101/2023.05.02.539098 — neuroscience — Posted on 2023-05-03
4020 Host-Microbiome Associations in Saliva Predict COVID-19 Severity
Alqaderi, H.; Altabtbaei, K.; Espinoza, J. L.; Bin-Hasan, S.; Alghounaim, M.; Alawady, A.; Altabtabae, A.; AlJamaan, S.; Devarajan, S.; AlShammari, T.; Eid, M. B.; Matsuoka, M.; Jang, H.; Dupont, C.; Freire, M.
10.1101/2023.05.02.539155 — immunology — Posted on 2023-05-03
4021 Chronic alcohol consumption dysregulates innate immune response to SARS-CoV-2 in the lung
Lewis, S. A.; Cinco, I. R.; Doratt, B. M.; Blanton, M. B.; Hoagland, C.; Davies, M.; Grant, K. A.; Messaoudi, I.
10.1101/2023.05.02.539139 — immunology — Posted on 2023-05-03
4022 The Hsf1-sHsp cascade has pan-antiviral activity in mosquitoes
Qu, J.; Schinkel, M.; Chiggiato, L.; Rosendo Machado, S.; Overheul, G. J.; Miesen, P.; van Rij, R. P.
10.1101/2023.02.21.529413 — microbiology — Posted on 2023-05-03
4024 Flow-induced mechanical coupling between perinuclear actin cap and nucleus governs spatiotemporal regulation of YAP transport
Ma, T.; Liu, X.; Su, H.; He, Y.; Wu, F.; Gao, C.; Li, K.; Liang, Z.; Zhang, D.; Zhang, X.; Hu, K.; Li, S.; Wang, L.; Wang, M.; Yue, S.; Hong, W.; Chen, X.; Zhang, J.; Deng, X.; Wang, P.; Fan, Y.
10.1101/2022.11.15.516697 — biophysics — Posted on 2023-05-03
4025 Ribosomal Frameshifting Selectively Modulates the Biosynthesis, Assembly, and Function of a Misfolded CFTR Variant
Carmody, P.; Roushar, F. J.; Tedman, A.; Herwig, M.; Kim, M.; McDonald, E. F.; Wong-Roushar, J.; Poirier, J.-L.; Zelt, N.; Pockrass, B.; McKee, A. G.; Kuntz, C. P.; Plate, L.; Penn, W. D.; Schlebach, J. P.
10.1101/2023.05.02.539166 — biochemistry — Posted on 2023-05-03
4029 Bacterial DNA on the skin surface overrepresents the viable skin microbiome
Acosta, E. M.; Little, K. A.; Bratton, B. P.; Lopez, J. G.; Mao, X.; Payne, A. S.; Donia, M. S.; Devenport, D.; Gitai, Z.
10.1101/2021.08.16.455933 — microbiology — Posted on 2023-05-03
4030 DrugMechDB: A Curated Database of Drug Mechanisms
Gonzalez-Cavazos, A. C.; Tanska, A.; Mayers, M. D.; Carvalho-Silva, D.; Sridharan, B.; Rewers, P. A.; Sankarlal, U.; Jagannathan, L.; Su, A. I.
10.1101/2023.05.01.538993 — bioinformatics — Posted on 2023-05-03
4033 Distributed representations of prediction error signals across the cortical hierarchy are synergistic
Gelens, F.; Aijala, J.; Komatsu, M.; Uran, C.; Jensen, M. A.; Miller, K. J.; Ince, R. A. A.; Vinck, M.; Canales-Johnson, A.
10.1101/2023.01.12.523735 — neuroscience — Posted on 2023-05-03
4034 Bumblebee mouthparts exhibit poor acuity for the detection of pesticides in nectar
Parkinson, R. H.; Scott, J.; Jones, H.; Dorling, A. L.; McDermott-Roberts, A. E.; Haslam, M.; Wright, G. A.
10.1101/2023.02.03.526956 — neuroscience — Posted on 2023-05-03
4035 SNP discovery by exome capture and resequencing in a pea genetic resource collection
AUBERT, G.; Kreplak, J.; Leveugle, M.; Duborjal, H.; Klein, A.; Boucherot, K.; Vieille, E.; Chabert-Martinello, M.; Cruaud, C.; Bourion, V.; Lejeune-Henaut, I.; Pilet-Nayel, M.-L.; Bouchenak-Khelladi, Y.; Francillonne, N.; Tayeh, N.; Pichon, J.-P.; Riviere, N.; Burstin, J.
10.1101/2022.08.03.502586 — genomics — Posted on 2023-05-03
4036 Developmental biomechanics and age polyethism in leaf-cutter ants
Pueffel, F.; Meyer, L.; Imirzian, N.; Roces, F.; Johnston, R. E.; Labonte, D.
10.1101/2023.02.13.528272 — developmental biology — Posted on 2023-05-03
4038 The functional specificity of CDC42 isoforms is caused by their distinct sub cellular localization
Ravichandran, Y.; Hanisch, J.; Murray, K.; Roca, V.; Dingli, F.; Loew, D.; Sabatet, V.; Boeda, B.; Stradal, T.; Etienne-Manneville, S.
10.1101/2023.02.27.528078 — cell biology — Posted on 2023-05-03
4039 A brainstem to hypothalamic arcuate nucleus GABAergic circuit drives feeding
Martinez de Morentin, P. B.; Gonzalez, J. A.; Martynova, Y.; Sylantyev, S.; Heisler, L. K.
10.1101/2023.05.03.538908 — neuroscience — Posted on 2023-05-03
4040 Autophagy is a cell-intrinsic driver of neural stem cell quiescence in hippocampal dentate gyrus development
Calatayud-Baselga, I.; Casares-Crespo, L.; Franch-Ibanez, C.; Guijarro-Nuez, J.; Sanz, P.; Mira, H.
10.1101/2023.05.03.539225 — neuroscience — Posted on 2023-05-03
4043 Common synaptic inputs and persistent inward currents of vastus lateralis motor units are reduced in older age
Guo, Y.; Jones, E. J.; Skarabot, J.; Inns, T.; Phillips, B. E.; Atherton, P. J.; Piasecki, M.
10.1101/2023.02.03.526933 — physiology — Posted on 2023-05-03
4044 Endothelial-specific reduction in Arf6 impairs insulin-stimulated vasodilation and skeletal muscle blood flow resulting in systemic insulin resistance
Islam, M. T.; Cai, J.; Allen, S.; Bramwell, R. C.; Mitton, J.; Horn, A. G.; Zhu, W.; Donato, A. J.; Holland, W. L.; Lesniewski, L. A.; Moreno, D. G.; Bloom, S. I.
10.1101/2023.05.02.539173 — physiology — Posted on 2023-05-03
4045 Scalable Log-ratio Lasso Regression Enhances Microbiome Feature Selection for Predictive Models
Fei, T.; Funnell, T.; Waters, N.; Raj, S. S.; Devlin, S. M.; Dai, A.; Miltiadous, O.; Shouval, R.; Lv, M.; Peled, J. U.; Ponce, D. M.; Perales, M.-A.; Gönen, M.; van den Brink, M. R. M.
10.1101/2023.05.02.538599 — bioinformatics — Posted on 2023-05-03
4046 A primary microcephaly-associated sas-6 mutation perturbs centrosome duplication, dendrite morphogenesis, and ciliogenesis in Caenorhabditis elegans
Bergwell, M.; Smith, A.; Smith, E.; Dierlam, C.; Duran, R.; Haastrup, E.; Napier-Jameson, R.; Seidel, R.; Potter, W.; Norris, A.; Iyer, J.
10.1101/2022.11.25.518003 — genetics — Posted on 2023-05-03
4048 Uncovering the multi-step process of stable microtubule bundle formation upon entry into quiescence
Laporte, D.; Massoni-Laporte, A.; LEfranc, C.; Dompierre, J.; Mauboules, D.; Nsamba, E. T.; Royou, A.; Gal, L.; Schuldiner, M.; Gupta, M.; Sagot, I.
10.1101/2023.05.02.539064 — cell biology — Posted on 2023-05-03
4051 Genetic manipulation of candidate phyla radiation bacteria provides functional insights into microbial dark matter
Wang, Y.; Gallagher, L. A.; Andrade, P. A.; Liu, A.; Humphreys, I. R.; Turkarslan, S.; Cutler, K. J.; Arrieta-Ortiz, M. L.; Li, Y.; Radey, M. C.; Cong, Q.; Baker, D.; Baliga, N. S.; Peterson, S. B.; Mougous, J. D.
10.1101/2023.05.02.539146 — microbiology — Posted on 2023-05-03
4053 Colon resident CD8+ T cells from people with HIV on antiretroviral therapy exhibit mitochondrial dysfunction and impaired responses
Das Adhikari, U.; Shah, P. V.; Froehle, L. M.; Linder, A. H.; Flagg, M.; Crawlings, C.; Junca, M. R.; Folarin, L.; Karim, F.; Li, J. Z.; Kloverpris, H.; Kwon, D. S.
10.1101/2023.05.02.539176 — immunology — Posted on 2023-05-03
4055 Modeling the cell-type specific mesoscale murine connectome with anterograde tracing experiments
Koelle, S.; Mastrovito, D.; Whitesell, J. D.; Hirokawa, K. E.; Zeng, H.; Meila, M.; Harris, J. A.; Mihalas, S.
10.1101/2023.05.02.539079 — neuroscience — Posted on 2023-05-03
4061 Preclinical evaluation of PHH-1V vaccine candidate against SARS-CoV-2 in non-human primates
Prenafeta, A.; Bech-Sabat, G.; Moros, S.; Barreiro, A.; Fernandez, A.; Canete, M.; Roca, M.; Gonzalez, L.; Garriga, C.; Confais, J.; Toussenot, M.; Contamin, H.; Pizzorno, A.; Rosa-Calatrava, M.; Pradenas, E.; Marfil, S.; Blanco, J.; Cebollada Rica, P.; Sistere-Oro, M.; Meyerhans, A.; Lorca, C.; Segales, J.; Prat, T.; March, R.; Ferrer, L.
10.1101/2022.12.13.520255 — immunology — Posted on 2023-05-03
4063 Adaptive planning depth in human problem solving
Eluchans, M.; Lancia, G. L.; Maselli, A.; D'Alessandro, M.; Gordon, J.; Pezzulo, G.
10.1101/2023.05.02.539099 — neuroscience — Posted on 2023-05-03
4065 Selective Enhancer Dependencies in MYC-Intact and MYC-Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma
Iyer, A. R.; Gurumurthy, A.; Kodgule, R.; Aguilar, A. R.; Saari, T.; Ramzan, A.; Rausch, D.; Gupta, J.; Hall, C. N.; Runge, J. S.; Weiss, M. B.; Rahmat, M.; Anyoha, R.; Fulco, C. P.; Ghobrial, I. M.; Engreitz, J. M.; Cieslik, M. P.; Ryan, R. J.
10.1101/2023.05.02.538892 — cancer biology — Posted on 2023-05-03
4068 Europe PMC Annotated Full-text Corpus for Gene/Proteins, Diseases and Organisms
Yang, X.; Saha, S.; Venkatesan, A.; Tirunagari, S.; Vartak, V.; McEntyre, J.
10.1101/2023.02.20.529292 — bioinformatics — Posted on 2023-05-03
4072 Single cell transcriptomics of the human parasite Schistosoma mansoni first intra-molluscan stage reveals tentative tegumental and stem cell regulators.
Soria, C. L. D.; Attenborough, T.; Lu, Z.; Graham, J.; Hall, C.; Thompson, S.; Andrews, T. G.; Rawlinson, K. A.; Berriman, M.; Rinaldi, G.
10.1101/2023.05.02.538881 — developmental biology — Posted on 2023-05-03
4074 Repeated Omicron infection alleviates SARS-CoV-2 immune imprinting
Yisimayi, A.; Song, W.; Wang, J.; Jian, F.; Yu, Y.; Chen, X.; Xu, Y.; Yang, S.; Niu, X.; Xiao, T.; Wang, J.; An, R.; Zhang, N.; Wang, Y.; Wang, P.; Zhao, L.; Sun, H.; Yu, L.; Gu, Q.; Shao, F.; Jin, R.; Shen, Z.; Xie, X. S.; Wang, Y.; Cao, Y.
10.1101/2023.05.01.538516 — immunology — Posted on 2023-05-03
4077 Ribosomal Frameshifting Selectively Modulates the Biosynthesis, Assembly, and Function of a Misfolded CFTR Variant
Carmody, P.; Roushar, F. J.; Tedman, A.; Herwig, M.; Kim, M.; McDonald, E. F.; Wong-Roushar, J.; Poirier, J.-L.; Zelt, N.; Pockrass, B.; McKee, A. G.; Kuntz, C. P.; Plate, L.; Penn, W. D.; Schlebach, J. P.
10.1101/2023.05.02.539166 — biochemistry — Posted on 2023-05-03
4080 Post-glacial expansion dynamics, not refugial isolation, shaped the genetic structure of a migratory bird, the yellow warbler
Miller, E. F.; Leonardi, M.; Xue, Z.; Beyer, R.; Krapp, M.; Somveille, M.; Somma, G. L.; Delser, P. M.; Manica, A.
10.1101/2021.05.10.443405 — evolutionary biology — Posted on 2023-05-03
4081 FORGEdb: a tool for identifying candidate functional variants and uncovering target genes and mechanisms for complex diseases.
Breeze, C. E.; Haugen, E.; Gutierrez-Arcelus, M.; Yao, X.; Teschendorff, A.; Beck, S.; Dunham, I.; Stamatoyannopoulos, J.; Franceschini, N.; Machiela, M.; Berndt, S.
10.1101/2022.11.14.516365 — genomics — Posted on 2023-05-03
4088 On the interpretation of transcriptome-wide association studies
de Leeuw, C.; Werme, J.; Savage, J.; Peyrot, W. J.; Posthuma, D.
10.1101/2021.08.15.456414 — genetics — Posted on 2023-05-03
4091 The landscape of tolerated genetic variation in humans and primates
Gao, H.; Hamp, T.; Ede, J.; Schraiber, J.; McRae, J.; Berk, M.; Yang, Y.; Dietrich, A.; Fiziev, P.; Kuderna, L.; Sundaram, L.; Wu, Y.; Adhikari, A.; Field, Y.; Chen, C.; Batzoglou, S.; Aguet, F.; Lemire, G.; Reimers, R.; Balick, D.; Janiak, M.; Kuhlwilm, M.; Orkin, J.; Manu, S.; Valenzuela, A.; Bergman, J.; Rousselle, M.; Silva, F.; Agueda, L.; Blanc, J.; Gut, M.; de Vries, D.; Goodhead, I.; Harris, R. A.; Raveendran, M.; Jensen, A.; Chuma, I.; Horvath, J.; Hvilsom, C.; Juan, D.; Frandsen, P.; Melo, F.; Bertuol, F.; Byrne, H.; Sampaio, I.; Farias, I.; Valsecchi, J.; Messias, M.; Silva, M.; Tri
10.1101/2023.05.01.538953 — genomics — Posted on 2023-05-02
4093 GABA, glutamatergic dynamics and BOLD contrast concurrently assessed using functional MR spectroscopy during a cognitive task
Craven, A. R.; Dwyer, G.; Ersland, L.; Kazimierczak, K.; Noeske, R.; Sandoy, L. B.; Johnsen, E.; Hugdahl, K.
10.1101/2023.05.02.539017 — neuroscience — Posted on 2023-05-02
4094 High-density volumetric super-resolution microscopy
Daly, S.; Ferreira Fernandes, J.; Bruggeman, E.; Handa, A.; Peters, R.; Benaissa, S.; Zhang, B.; Beckwith, J. S.; Sanders, E. W.; Sims, R. R.; Klenerman, D.; Davis, S. J.; O'Holleran, K.; Lee, S. F.
10.1101/2023.05.02.539032 — biophysics — Posted on 2023-05-02
4096 Structural Insights into the Iron Nitrogenase Complex
Schmidt, F. V.; Schulz, L.; Zarzycki, J.; Oehlmann, N. N.; Prinz, S.; Erb, T. J.; Rebelein, J. G.
10.1101/2023.05.02.539077 — biochemistry — Posted on 2023-05-02
4097 A global catalog of whole-genome diversity from 233 primate species
Kuderna, L. F. K.; Gao, H.; Janiak, M. C.; Kuhlwilm, M.; Orkin, J. D.; Bataillon, T.; Manu, S.; Valenzuela, A.; Bergman, J.; Rouselle, M.; Silva, F. E.; Agueda, L.; Blanc, J.; Gut, M.; de Vries, D.; Goodhead, I.; Harris, R. A.; Raveendran, M.; Jensen, A.; Chuma, I. S.; Horvath, J.; Hvilsom, C.; Juan, D.; Frandsen, P.; Schraiber, J. G.; de Melo, F. R.; Bertuol, F.; Byrne, H.; Sampaio, I.; Farias, I.; Valsecchi do Amaral, J.; Messias, M.; da Silva, M. N. F.; Trivedi, M.; Rossi, R.; Hrbek, T.; Andriaholinirina, N.; Rabarivola, C. J.; Zaramody, A.; Jolly, C. J.; Phillips-Conroy, J.; Wilkerson, G.;
10.1101/2023.05.02.538995 — genomics — Posted on 2023-05-02
4098 Genetic and Environmental interactions contribute to immune variation in rewilded mice
Oyesola, O. O.; Downie, A. E.; Howard, N.; Barre, R. S.; Kiwanuka, K. N.; Chen, Y.-H.; Menezes, A.; Lee, S. C.; Devlin, C.; Mondragon-Palomino, O.; Silva Souza, C. O.; Herrmann, C.; Koralov, S. B.; Cadwell, K.; Graham, A. L. B.; Loke, P.
10.1101/2023.03.17.533121 — immunology — Posted on 2023-05-02
4100 A novel biopolymer for mucosal adjuvant against respiratory pathogens
Hoover, A. R.; More, S.; Liu, K.; West, C. L.; Valerio, T. I.; Yu, N.; Villalva, C.; Kumar, A.; Alleruzzo, L.; Lam, S. S. K.; Hode, T.; Zhao, M.; Papin, J. F.; Chen, W. R.
10.1101/2022.09.07.506979 — bioengineering — Posted on 2023-05-02
4104 A leaky integrate-and-fire computational model based on the connectome of the entire adult Drosophila brain reveals insights into sensorimotor processing
Shiu, P. K.; Sterne, G. R.; Spiller, N.; Franconville, R.; Sandoval, A.; Zhou, J.; Simha, N.; Kang, C. H.; Yu, S.; Kim, J. S.; Dorkenwald, S.; Matsliah, A.; Schlegel, P.; Yu, S.-c.; McKellar, C. E.; Sterling, A.; Costa, M.; Eichler, K.; Jefferis, G. S. X. E.; Murthy, M.; Bates, A. S.; Eckstein, N.; Funke, J.; Bidaye, S. S.; Hampel, S.; Seeds, A. M.; Scott, K.
10.1101/2023.05.02.539144 — neuroscience — Posted on 2023-05-02
4108 Controlled tumor heterogeneity in a co-culture system by 3D bio-printed tumor-on-chip model
Moghimi, N.; Hosseini, S. A.; Dalan, A. B.; Mohammadizadeh, D.; Goldman, A.; Kohandel, M.
10.1101/2023.05.02.539106 — bioengineering — Posted on 2023-05-02
4109 Synergistic Binding of the Halide and Cationic Prime Substrate of the L-Lysine 4-Chlorinase, BesD, in Both Ferrous and Ferryl States
Slater, J. W.; Neugebauer, M. E.; McBride, M. J.; Sil, D.; Lin, C.-Y.; Katch, B. J.; Boal, A. K.; Chang, M. C.; Silakov, A.; Krebs, C.; Bollinger, J. M.
10.1101/2023.05.02.539147 — biochemistry — Posted on 2023-05-02
4111 Phenotypic Differences in Adult and Fetal Dermal Fibroblast Responses to Mechanical Tension
Short, W. D.; Parikh, U. M.; Templeman, N.; Olutoye, O. O.; Blum, A.; Colchado, D.; Padon, B.; Kaul, A.; Li, H.; Vangapandu, H. V.; Jung, O. S.; Bommekal, P.; Kogan, P.; Fahrenholtz, M. M.; Coarfa, C.; Balaji, S.
10.1101/2020.09.30.319749 — molecular biology — Posted on 2023-05-02
4113 Unique genomic sequences in a novel Mycobacterium avium subsp. hominissuis lineage enable fine scale transmission route tracing during pig movement
Komatsu, T.; Ohya, K.; Ota, A.; Nishiuchi, Y.; Yano, H.; Matsuo, K.; Odoi, J. O.; Suganuma, S.; Sawai, K.; Hasebe, A.; Asai, T.; Yanai, T.; Fukushi, H.; Wada, T.; Yoshida, S.; Arikawa, K.; Ito, T.; Kawai, M.; Ato, M.; Baughn, A. D.; Iwamoto, T.; MARUYAMA, F.
10.1101/2022.04.04.487006 — microbiology — Posted on 2023-05-02
4115 Parallel Evolution of Linezolid Resistant Staphylococcus aureus in Patients with Cystic Fibrosis
Pitcher, N. J.; Feder, A.; Bolden, N.; Zirbes, C. F.; Pamatmat, A. J.; Boyken, L. D.; Hill, J. J.; Thurman, A.; Reeb, V.; Porterfield, H. S.; Moustafa, A. M.; Planet, P. J.; Fischer, A. J.
10.1101/2023.05.02.539145 — microbiology — Posted on 2023-05-02
4117 Lipopolysaccharide integrity primes bacterial sensitivity to a cell wall-degrading intermicrobial toxin
Trotta, K. L.; Hayes, B. M.; Schneider, J. P.; Wang, J.; Todor, H.; Rockefeller Grimes, P.; Zhao, Z.; Hatleberg, W.; Silvis, M. R.; Kim, R.; Koo, B.-M.; Basler, M.; Chou, S.
10.1101/2023.01.20.524922 — microbiology — Posted on 2023-05-02
4118 Toxic anti-phage defense proteins inhibited by intragenic antitoxin proteins
Zhong, A.; Jiang, X.; Hickman, A. B.; Klier, K.; Teodoro, G. I. C.; Dyda, F.; Laub, M. T.; Storz, G.
10.1101/2023.05.02.539157 — microbiology — Posted on 2023-05-02
4121 Integrated analysis of spatial multi-omics with SpatialGlue
Long, Y.; Ang, K. S.; Liao, S.; Sethi, R.; Heng, Y.; Zhong, C.; Xu, H.; Husna, N.; Jian, M.; Ng, L. G.; Chen, A.; Gascoigne, N. R.; Xu, X.; Chen, J.
10.1101/2023.04.26.538404 — bioinformatics — Posted on 2023-05-02
4122 DrugMechDB: A Curated Database of Drug Mechanisms
Gonzalez-Cavazos, A. C.; Tanska, A.; Mayers, M. D.; Sridharan, B.; Rewers, P. A.; Sankarlal, U.; Jagannathan, L.; Carvalho-Silva, D.; Su, A. I.
10.1101/2023.05.01.538993 — bioinformatics — Posted on 2023-05-02
4124 Biosynthetic Enzyme-guided Disease Correlation Connects Gut Microbial Metabolites Sulfonolipids to Inflammatory Bowel Disease Involving TLR4 Signaling
Older, E. A.; Zhang, J.; Ferris, Z. E.; Xue, D.; Zhong, Z.; Mitchell, M. K.; Madden, M.; Wang, Y.; Chen, H.; Nagarkatti, P.; Nagarkatti, M.; Fan, D.; Ellermann, M.; LI, Y.; Li, J.
10.1101/2023.03.16.533047 — biochemistry — Posted on 2023-05-02
4131 Desmosomal cell cohesion and epidermal differentiation are modulated by dolichol phosphate mannosyltransferase 1 (DPM1) through SERPINB5-dependent mechanisms
Rathod, M.; Franz, H.; Beyersdorfer, V.; Wanuske, M.-T.; Fischer, K. L.; Hanns, P.; Stüdle, C.; Zimmermann, A.; Buczak, K.; Schinner, C.; Spindler, V.
10.1101/2022.12.28.522133 — cell biology — Posted on 2023-05-02
4132 Clr4SUV39H1 ubiquitination and non-coding RNA mediate transcriptional silencing via heterochromatic phase transitions
Kim, H.-S.; Roche, B.; Bhattacharjee, S.; Todeschini, L.; Chang, A.-Y.; Hammell, C.; Verdel, A.; Martienssen, R. A.
10.1101/2021.01.08.425919 — molecular biology — Posted on 2023-05-02
4133 Variability and Bias in Microbiome Metagenomic Sequencing: an Interlaboratory Study Comparing Experimental Protocols
Forry, S. P.; Servetas, S. L.; Kralj, J. G.; Soh, K.; Hadjithomas, M.; Carlin, M.; de Amorim, M. G.; Auch, B.; Bakker, M. G.; Bartelli, T. F.; Bustamante, J. P.; Cassol, I.; Chalita, M.; Dias-Neto, E.; Gohl, D.; Haruna, M. T.; Kazantseva, J.; Menzel, P.; Moda, B. S.; Neuberger-Castillo, L.; Nunes, D.; Patel, I. R.; Peralta, R. D.; Saliou, A.; Schwarzer, R.; Sevilla, S.; Takenaka, I. K. T. M.; Wang, J.; Knight, R.; Gevers, D.; Jackson, S. A.
10.1101/2023.04.28.538741 — microbiology — Posted on 2023-05-02
4134 Harmonized diffusion MRI data and white matter measures from the Adolescent Brain Cognitive Development Study
Cetin-Karayumak, S.; Zhang, F.; Billah, T.; Zekelman, L.; Makris, N.; Pieper, S.; O'Donnell, L. J.; Rathi, Y.
10.1101/2023.04.04.535587 — neuroscience — Posted on 2023-05-02
4135 Brain state and cortical layer-specific mechanisms underlying perception at threshold
Morton, M. P.; Denagamage, S.; Blume, I. J.; Reynolds, J. H.; Jadi, M. P.; Nandy, A. S.
10.1101/2021.11.16.468866 — neuroscience — Posted on 2023-05-02
4136 Experience-Dependent Plasticity in Nucleus Laminaris of the Barn Owl
Carr, C. E.; Wang, T.; Kraemer, I.; Capshaw, G.; Ashida, G.; Koeppl, C.; Kempter, R.; Kuokkanen, P. T.
10.1101/2023.02.02.526884 — neuroscience — Posted on 2023-05-02
4137 Neural interactions in the human frontal cortex dissociate reward and punishment learning
Combrisson, E.; Basanisi, R.; Gueguen, M.; Rheims, S.; Kahane, P.; Bastin, J.; Brovelli, A.
10.1101/2023.05.02.539138 — neuroscience — Posted on 2023-05-02
4138 High-content microscopy reveals a morphological signature of bortezomib resistance
Kelley, M. E.; Berman, A. Y.; Stirling, D. R.; Cimini, B. A.; Han, Y.; Singh, S.; Carpenter, A. E.; Kapoor, T. M.; Way, G. P.
10.1101/2023.05.02.539137 — cancer biology — Posted on 2023-05-02
4141 Collection of Biospecimens from the Inspiration4 Mission Establishes the Standards for the Space Omics and Medical Atlas (SOMA)
Overbey, E. G.; Ryon, K.; Kim, J.; Tierney, B.; Klotz, R.; Ortiz, V.; Mullane, S.; Schmidt, J. C.; MacKay, M.; Damle, N.; Najjar, D.; Matei, I.; Patras, L.; Medina, J. S. G.; Kleinman, A.; Hirschberg, J. W.; Proszynski, J.; Narayanan, S. A.; Schmidt, C. M.; Afshin, E. E.; Innes, L.; Saldarriaga, M. M.; Schmidt, M. A.; Granstein, R. D.; Shirah, B.; Yu, M.; Lyden, D.; Mateus, J.; Mason, C. E.
10.1101/2023.05.02.539108 — molecular biology — Posted on 2023-05-02
4142 Persistent delay in maturation of the developing gut microbiota in infants with cystic fibrosis
Salerno, P. E.; Verster, A. J.; Valls, R. A.; Barrack, K. E.; Price, C. E.; Madan, J. C.; O'Toole, G. A.; Ross, B. D.
10.1101/2023.05.02.539134 — microbiology — Posted on 2023-05-02
4143 Evaluation of Expanded 2-Aminobenzothiazole Library for Inhibition of Pseudomonas aeruginosa Virulence Phenotypes
Fihn, C.; Lembke, H.; Gaulin, J.; Bouchard, P.; Penningroth, M. R.; Crone, K.; Vogt, G.; Gilbertsen, A.; Ayotte, Y.; CouthinodeOliveira, L.; Serrano-Wu, M.; Drouin, N.; Hung, D.; Hunter, R. C.; Carlson, E. E.
10.1101/2023.05.02.539119 — microbiology — Posted on 2023-05-02
4144 Diverging maternal and infant cord antibody functions from SARS-CoV-2 infection and vaccination in pregnancy
Adhikari, E. H.; Lu, P.; Kang, Y. J.; McDonald, A. R.; Pruszynski, J. E.; Bates, T. A.; McBride, S. K.; Trank-Greene, M.; Tafesse, F. G.; Lu, L. L.
10.1101/2023.05.01.538955 — immunology — Posted on 2023-05-02
4147 Single Cell Resolution Spatial Mapping of Human Hematopoiesis Reveals Aging-Associated Topographic Remodeling
Sarachakov, A.; Svekolkin, V.; Varlamova, A.; Galkin, I.; Valencia, I.; Unkenholz, C.; Pannellini, T.; Akaeva, A.; Smirnova, S.; Ovcharov, P.; Polyakova, M.; Tabakov, D.; Postovalova, E.; Sethi, I.; Shin, N.; Bagaev, A.; Itkin, T.; Crane, G.; Kluk, M. J.; Geyer, J.; Inghirami, G.; Patel, S.
10.1101/2023.04.28.538715 — systems biology — Posted on 2023-05-02
4149 Discovery and characterization of highly potent and selective covalent inhibitors of SARS-CoV-2 PLpro
Wu, J.; Vaid, T.; Kim, H.; Lu, J.; Demissie, R.; Lee, H.; Fung, L. W.- M.; Chen, J.; Xi, C.; Yang, Z.; Huang, Y.; Zhang, Z.; Zhang, J.; Yan, F.; Johnson, M. E.; Li, M.
10.1101/2023.05.02.539082 — pharmacology and toxicology — Posted on 2023-05-02
4152 MDverse: Shedding Light on the Dark Matter of Molecular Dynamics Simulations
Tiemann, J. K. S.; Szczuka, M.; Bouarroudj, L.; Oussaren, M.; Garcia, S.; Howard, R. J.; Delemotte, L.; Lindahl, E.; Baaden, M.; Lindorff-Larsen, K.; Chavent, M.; Poulain, P.
10.1101/2023.05.02.538537 — bioinformatics — Posted on 2023-05-02
4153 Backscattering Amplitude in Ultrasound Localization Microscopy
Renaudin, N.; Pezet, S.; Ialy-Radio, N.; Demene, C.; Tanter, M.
10.1101/2023.04.27.538586 — bioengineering — Posted on 2023-05-02
4155 Genome-wide coancestry reveals details of ancient and recent male-driven reticulation in baboons
Sorensen, E. F.; Harris, R. A.; Zhang, L.; Raveendran, M.; Kuderna, L. F. K.; Walker, J. A.; Storer, J. M.; Kuhlwilm, M.; Fontsere, C.; Seshadri, L.; Bergey, C. M.; Burrell, A. S.; Bergmann, J.; Phillips-Conroy, J. E.; Shiferaw, F.; Chiou, K. L.; Chuma, I. S.; Keyyu, J. D.; Fischer, J.; Gingras, M.-C.; Salvi, S.; Doddapaneni, H.; Schierup, M. H.; Batzer, M. A.; Jolly, C. J.; Knauf, S.; Zinner, D.; Farh, K. K.- H.; Marques-Bonet, T.; Munch, K.; Roos, C.; Rogers, J.
10.1101/2023.05.02.539112 — evolutionary biology — Posted on 2023-05-02
4156 How environmental drivers of spatial synchrony interact
Reuman, D. C.; Castorani, M. C.; Cavanaugh, K. C.; Sheppard, L. W.; Walter, J. A.; Bell, T. W.
10.1101/2023.05.02.539141 — ecology — Posted on 2023-05-02
4158 Specification of distinct cell types in a sensory-adhesive organ for metamorphosis in the Ciona larva
Johnson, C. J.; Razy-Krajka, F.; Zeng, F.; Piekarz, K. M.; Biliya, S.; Rothbacher, U.; Stolfi, A.
10.1101/2023.05.02.539060 — developmental biology — Posted on 2023-05-02
4159 Isoform Specific Regulation of Adenylyl Cyclase 5 by Gβγ
Yen, Y.-C.; Li, Y.; Chen, C.-L.; Klose, T.; Watts, V. J.; Dessauer, C. W.; Tesmer, J. J. G.
10.1101/2023.05.02.539090 — biophysics — Posted on 2023-05-02
4161 RenSeq of Silphium integrifolium Reveals a Biotic Gradient for Disease Resistance
Keepers, K. G.; Peterson, K.; Raduski, A. R.; Turner, K. M.; van Tassel, D.; Smith, K. P.; Harkess, A.; Bever, J. D.; Brandvain, Y.
10.1101/2023.05.02.539110 — evolutionary biology — Posted on 2023-05-02
4165 Cellular Dynamics of Skeletal Muscle Regeneration
Collins, B. C.; Shapiro, J. B.; Scheib, M. M.; Musci, R. V.; Verma, M.; Kardon, G.
10.1101/2023.05.02.538744 — cell biology — Posted on 2023-05-02
4168 Tetraspanin CD82 maintains HTLV-1 biofilm polarization and is required for efficient viral transmission
Arone, C.; Martial, S.; Burlaud-Gaillard, J.; Thoulouze, M.-I.; Roingeard, P.; Dutartre, H.; Muriaux, D.
10.1101/2023.05.02.538526 — microbiology — Posted on 2023-05-02
4171 Repeated Omicron infection alleviates SARS-CoV-2 immune imprinting
Yisimayi, A.; Song, W.; Wang, J.; Jian, F.; Yu, Y.; Chen, X.; Xu, Y.; Yang, S.; Niu, X.; Xiao, T.; Wang, J.; An, R.; Zhang, N.; Wang, Y.; Wang, P.; Zhao, L.; Sun, H.; Yu, L.; Gu, Q.; Shao, F.; Jin, R.; Shen, Z.; Xie, X. S.; Wang, Y.; Cao, Y.
10.1101/2023.05.01.538516 — immunology — Posted on 2023-05-02
4172 Puromycin reveals a distinct conformation of neuronal ribosomes
Anadolu, M. N.; Sun, J.; Li, J. T.-Y.; Graber, T.; Ortega, J.; Sossin, W. S.
10.1101/2023.05.02.539124 — neuroscience — Posted on 2023-05-02
4177 Ghrelin delays premature aging in Hutchinson-Gilford progeria syndrome
Ferreira-Marques, M.; Carvalho, A.; Franco, A. C.; Leal, A.; Botelho, M.; Carmo-Silva, S.; Aguas, R.; Cortes, L.; Lucas, V.; Real, A. C.; Lopez-Otin, C.; Nissan, X.; Pereira de Almeida, L.; Cavadas, C.; Aveleira, C. A.
10.1101/2023.05.02.539084 — physiology — Posted on 2023-05-02
4178 Sperm Toolbox - A selection of small molecules to study human spermatozoa
Gruber, F. S.; Richardson, A.; Johnston, Z. C.; Myles, R.; Norcross, N.; Day, D.; Georgiou, I.; Sesma Sanz, L.; Wilson, C.; Read, K. D.; Martins da Silva, S.; Barratt, C. L.; Gilbert, I. H.; Swedlow, J. R.
10.1101/2023.05.02.539126 — pharmacology and toxicology — Posted on 2023-05-02
4179 Age-related increases in fibroblasts-secreted IGFBP2 increase melanoma cell invasion and lipid synthesis.
Alicea, G. M.; Portuallo, M. E.; Patel, P.; Fane, M. E.; Carey, A.; Speicher, D. W.; Kossenkov, A.; Rebecca, V. W.; Wirtz, D.; Weeraratna, A. T.
10.1101/2023.05.02.539059 — cancer biology — Posted on 2023-05-02
4185 A Narrow Range of Transcript-error Rates Across the Tree of Life
Li, W.; Baehr, S.; Marasco, M.; Reyes, L.; Brister, D.; Pikaard, C.; Gout, J.-F.; Vermulst, M.; Lynch, M.
10.1101/2023.05.02.538944 — evolutionary biology — Posted on 2023-05-02
4189 DNA Combing versus DNA Spreading and the Separation of Sister Chromatids
Meroni, A.; Wells, S.; Fonseca, C.; Ray Chaudhuri, A.; Caldecott, K.; Vindigni, A.
10.1101/2023.05.02.539129 — molecular biology — Posted on 2023-05-02
4190 Direct translation of incoming retroviral RNA genomes
Koppke, J.; Keller, L.-E.; Stuck, M.; Arnow, N. D.; Bannert, N.; Cingoz, O.
10.1101/2023.05.02.539066 — microbiology — Posted on 2023-05-02
4191 Uncovering the temporal dynamics and regulatory networks of thermal stress response in a hyperthermophile using transcriptomics and proteomics
Gruenberger, F.; Schmid, G.; El-Ahmad, Z.; Fenk, M.; Vogl, K.; Reichelt, R.; Hausner, W.; Urlaub, H.; Lenz, C.; Grohmann, D.
10.1101/2023.05.02.539125 — microbiology — Posted on 2023-05-02
4194 High carbohydrate to protein ratio promotes changes in intestinal microbiota and host metabolism in rainbow trout (Oncorhynchus mykiss) fed plant-based diet.
Defaix, R.; Lokesh, J.; Ghislain, M.; Le Bechec, M.; Marchand, M.; Veron, V.; Surget, A.; Biasutti, S.; Terrier, F.; Pigot, T.; Panserat, S.; RICAUD, K.
10.1101/2023.05.02.539058 — molecular biology — Posted on 2023-05-02
4195 Meta-learning in head fixed mice navigating in virtual reality: A Behavioral Analysis
Zhao, X.; Gattoni, R.; Kozlosky, A.; Jacobs, A.; Morrow, C.; Lindo, S.; Spruston, N.
10.1101/2023.05.01.538936 — neuroscience — Posted on 2023-05-02
4196 Towards Preclinical Validation of Arbaclofen (R-baclofen) Treatment for 16p11.2 Deletion Syndrome
Gundersen, B. B.; O'Brien, W. T.; Schaffler, M. D.; Schultz, M. N.; Tsukahara, T.; Lorenzo, S. M.; Nalesso, V.; Clayton, A. H. L.; Abel, T.; Crawley, J. N.; Datta, S. R.; Herault, Y.
10.1101/2023.05.01.538987 — neuroscience — Posted on 2023-05-02
4197 The astrocyte alpha 1-adrenoreceptor is a key component of the neuromodulatory system in mouse visual cortex.
Wahis, J.; Akkaya, C.; Kirunda, A. M.; Mak, A.; Zeise, K.; Verhaert, J.; Gasparyan, H.; Hovhannisyan, S.; Holt, M. G.
10.1101/2023.05.02.538934 — neuroscience — Posted on 2023-05-02
4199 Upregulation of steroidogenesis is associated with coma in human cerebral malaria
Abdrabou, W.; Gupta, H.; Sahu, P. K.; Mohanty, A. K.; Pattnaik, R.; Hoffman, A.; Mohanty, S.; Wassmer, S.; Idaghdour, Y.
10.1101/2023.05.01.538900 — systems biology — Posted on 2023-05-02
4204 Mechanisms of Resistance to CAR-T cell Immunotherapy: Insights from a Mathematical Model
Santurio, D. S.; Paixao, E. A.; Barros, L. R. C.; Almeida, R. C.; Fassoni, A. C.
10.1101/2023.05.01.538974 — cancer biology — Posted on 2023-05-02
4205 Beyond Alternans: Detection of Higher-Order Periodicity in Ex-Vivo Human Ventricles Before Induction of Ventricular Fibrillation
Iravanian, S.; Uzelac, I.; Shah, A.; Toye, M. J.; Lloyd, M.; Burke, M. A.; Daneshmand, M. A.; Attia, T. S.; Vega, J. D.; Merchant, F. M.; Cherry, E. M.; Bhatia, N. K.; Fenton, F. H.
10.1101/2023.05.01.539003 — biophysics — Posted on 2023-05-02
4206 DrugMechDB: A Curated Database of Drug Mechanisms
Su, A. I.; Gonzalez-Cavazos, A. C.; Tanska, A.; Mayers, M. D.; Sridharan, B.; Rewers, P. A.; Sankarlal, U.; Jagannathan, L.; Carvalho-Silva, D.
10.1101/2023.05.01.538993 — bioinformatics — Posted on 2023-05-02
4210 Chromatin context-dependent effects of epigenetic drugs on CRISPR-Cas9 editing
Schep, R.; Trauernicht, M.; Morris, B.; Vergara, X.; Beijersbergen, R.; van Steensel, B.
10.1101/2023.05.02.539047 — genomics — Posted on 2023-05-02
4211 Genome dynamics across the evolutionary transition to endosymbiosis
Siozios, S.; Nadal Jimenez, P.; Azagi, T.; Sprong, H.; Frost, C. L.; Parratt, S. R.; Taylor, G.; Brettell, L.; Liew, K. C.; Croft, L.; King, K. C.; Brockhurst, M. A.; Hypsa, V.; Novakova, E.; Darby, A. C.; Hurst, G. D. D.
10.1101/2023.05.02.539033 — genomics — Posted on 2023-05-02
4213 Habitat fragmentation selects for low dispersal in an ant species
Finand, B.; Loeuille, N.; Bocquet, C.; Federici, P.; Ledamoisel, J.; Monnin, T.
10.1101/2023.05.02.539042 — evolutionary biology — Posted on 2023-05-02
4216 Strong breeding colony fidelity in northern gannets following High Pathogenicity Avian Influenza Virus (HPAIV) outbreak
Gremillet, D.; Ponchon, A.; Provost, P.; Gamble, A.; Abed-Zahar, M.; Bernard, A.; Courbin, N.; Delavaud, G.; Deniau, A.; Fort, J.; Hamer, K. C.; Jeavons, R.; Lane, J. V.; Langley, L.; Matthiopoulos, J.; Poupart, T.; Prudor, A.; Stephens, N.; Trevail, A.; Wanless, S.; Votier, S. C.; Jeglinski, J. W. E.
10.1101/2023.05.02.539030 — ecology — Posted on 2023-05-02
4220 The endoplasmic reticulum stress sensor IRE1 regulates collagen secretion through the enforcement of the proteostasis factor P4HB/PDIA1 contributing to liver damage and fibrosis
Hazari, Y.; Urra, H.; Lopez, V. A. G.; Diaz, J.; Tamburini, G.; Milani, M.; Pihan, P.; Durand, S.; Aprahamia, F.; Baxter, R.; Huang, M.; Dong, X. C.; Vihinen, H.; Gonzalez, A. B.; Godoy, P.; Criollo, A.; Ratziu, V.; Foufelle, F.; Hengstler, J. G.; Jokitalo, E.; Maitre, B. B.; Maiers, J. L.; Plate, L.; Kroemer, G.; Hetz, C.
10.1101/2023.05.02.538835 — cell biology — Posted on 2023-05-02
4226 Tricontinental detection of Streptococcus pyogenes M1UK: A call for wider research and active surveillance.
Vieira, A.; Soo, V. W.; Li, H. K.; Zhi, X.; Reeves, L.; Huse, K. K.; Mok, K. Y.; Cowen, O.; Jauneikaite, E.; Coelho, J.; Sriskandan, S.
10.1101/2023.04.30.538858 — microbiology — Posted on 2023-05-02
4232 Neighborhood air pollution is negatively associated with neurocognitive maturation in early adolescence
Kardan, O.; Sereeyothin, C.; Schertz, K. E.; Angstadt, M.; Weigard, A.; Berman, M. G.; Rosenberg, M. D.
10.1101/2023.04.28.538763 — neuroscience — Posted on 2023-05-02
4234 Inferring control objectives in a virtual balancing task in humans and monkeys
Sadeghi, M.; Sharif Razavian, R.; Bazzi, S.; Chowdhury, R. H.; Batista, A. P.; Loughlin, P. J.; Sternad, D.
10.1101/2023.05.02.539055 — neuroscience — Posted on 2023-05-02
4238 Spatial transcriptomic analysis of adult hippocampal neurogenesis in the human brain
Simard, S.; Rahimian, R.; Davoli, M. A.; Theberge, S.; Matosin, N.; Turecki, G.; Nagy, C.; Mechawar, N.
10.1101/2023.05.02.539011 — neuroscience — Posted on 2023-05-02
4239 Establishment and application of unbiased in vitro drug screening assays for the identification of compounds against Echinococcus granulosus s.s.
Kaethner, M.; Preza, M.; Kaempfer, T.; Zumstein, P.; Tamponi, C.; Varcasia, A.; Hemphill, A.; Brehm, K.; Lundström-Stadelmann, B.
10.1101/2023.05.02.539024 — pharmacology and toxicology — Posted on 2023-05-02
4240 mTOR Inhibition Suppresses Salinomycin-Induced Ferroptosis in Breast Cancer Stem Cells by Ironing Out Mitochondrial Dysfunctions
Cosialls, E.; Pacreau, E.; Ceccacci, S.; Elhage, R.; Duruel, C.; Desterke, C.; Roger, K.; Guerrera, C.; Ducloux, R.; Souquere, S.; Pierron, G.; Nemazanyy, I.; Kelly, M.; Dalmas, E.; Chang, Y.; Goffin, V.; Mehrpour, M.; Hamai, A.
10.1101/2023.05.02.539040 — cancer biology — Posted on 2023-05-02
4242 Renal tubular function and morphology revealed in kidney without labeling using three-dimensional dynamic optical coherence tomography
Mukherjee, P.; Fukuda, S.; Lukmanto, D.; Tran, T. H.; Okada, K.; Makita, S.; El-Sadek, I. A.; Lim, Y.; Yasuno, Y.
10.1101/2023.05.01.539010 — bioengineering — Posted on 2023-05-02
4243 Sulfur oxidation and reduction are coupled to nitrogen fixation in the roots of a salt marsh foundation plant species
Rolando, J. L.; Kolton, M.; Song, T.; Liu, Y.; Pinamang, P.; Conrad, R. E.; Morris, J. T.; Konstantinidis, K. T.; Kostka, J. E.
10.1101/2023.05.01.538948 — microbiology — Posted on 2023-05-02
4245 Secreted long non-coding RNAs Gadlor1 and Gadlor2 aggravate cardiac remodelling during pressure overload by affecting multiple cardiac cell types
Keles, M.; Grein, S.; Froese, N.; Wirth, D.; Trogisch, F. A.; Wardman, R.; Hemanna, S.; Weinzierl, N.; Reiners-Koch, P.-S.; Uhlig, S.; Lomada, S.; Dittrich, G. M.; Szaroszyk, M.; Haustein, R.; Hegermann, J.; Martin Garrido, A.; Bauersachs, J.; Frank, D.; Frey, N.; Bieback, K.; Cordero, J.; Dobreva, G.; Wieland, T.; Heineke, J.
10.1101/2022.09.19.508486 — systems biology — Posted on 2023-05-02
4246 Dynamic multi-OMICs of glioblastoma reveal sensitivity to neddylation inhibition dependent on nuclear PTEN and DNA replication pathways
Ferdosi, S. R.; Taylor, B.; Lee, M.; Peng, S.; Tang, N.; Bybee, R.; Reid, G.; Hartmen, L.; Garcia-Mansfield, K.; Sharma, R.; Pirrotte, P.; Furnari, F.; Dhruv, H. D.; Berens, M. E.
10.1101/2020.07.21.212571 — cancer biology — Posted on 2023-05-02
4248 The landscape of tolerated genetic variation in humans and primates
Gao, H.; Hamp, T.; Ede, J.; Schraiber, J.; McRae, J.; Berk, M.; Yang, Y.; Dietrich, A.; Fiziev, P.; Kuderna, L.; Sundaram, L.; Wu, Y.; Adhikari, A.; Field, Y.; Chen, C.; Batzoglou, S.; Aguet, F.; Lemire, G.; Reimers, R.; Balick, D.; Janiak, M.; Kuhlwilm, M.; Orkin, J.; Manu, S.; Valenzuela, A.; Bergman, J.; Rousselle, M.; Silva, F.; Agueda, L.; Blanc, J.; Gut, M.; de Vries, D.; Goodhead, I.; Harris, R. A.; Raveendran, M.; Jensen, A.; Chuma, I.; Horvath, J.; Hvilsom, C.; Juan, D.; Frandsen, P.; Melo, F.; Bertuol, F.; Byrne, H.; Sampaio, I.; Farias, I.; Valsecchi, J.; Messias, M.; Silva, M.; Tri
10.1101/2023.05.01.538953 — genomics — Posted on 2023-05-02
4255 SIRT1 regulates DNA damage signaling through the PP4 phosphatase complex
Rasti, G.; Becker, M.; Vazquez, B. N.; Espinosa-Alcantud, M.; Fernandez-Duran, I.; Gamez-Garcia, A.; Gonzalez-Nieto, J.; Bosch-Presegue, L.; Marazuela-Duque, A.; Segura-Bayona, S.; Ianni, A.; Bech-Serra, J.-J.; Scher, M.; Serrano, L.; Shankavaram, U.; Erdjument-Bromage, H.; Tempst, P.; Reinberg, D.; Olivella, M.; Stracker, T.; de la Torre, C.; Vaquero, A.
10.1101/2022.09.29.510108 — molecular biology — Posted on 2023-05-02
4257 Organic cation transporter 2 contributes to SSRI antidepressant efficacy by controlling tryptophan availability in the brain
Orrico-Sanchez, A.; Guiard, B.; Manta, S.; Callebert, J.; Launay, J.-M.; Louis, F.; Paccard, A.; Gruszczynski, C.; Betancur, C.; Vialou, V.; Gautron, S. L.
10.1101/2023.02.14.528444 — neuroscience — Posted on 2023-05-02
4258 Puberty and motherhood promote region-specific maturation of doublecortin cells in olfactory circuits of mice
Esteve-Perez, R.; Prina, M.; Navarro-Moreno, C.; Abellan-Alvaro, M.; Barneo-Munoz, M.; Lanuza, E.; Sanchez-Catalan, M. J.; Martinez-Garcia, F.; Agustin-Pavon, C.; Torres-Perez, J. V.
10.1101/2023.02.08.527694 — neuroscience — Posted on 2023-05-02
4260 The response to drought-stressed host plants varies among herbivorous mite populations from a climate gradient
Migeon, A.; Auger, P.; Fossati-Gaschigard, O.; Hufbauer, R. A.; Miranda, M.; Zriki, G.; Navajas, M.
10.1101/2021.10.21.465244 — zoology — Posted on 2023-05-02
4261 Rapid protein stability prediction using deep learning representations
Blaabjerg, L. M.; Kassem, M. M.; Good, L. L.; Jonsson, N.; Cagiada, M.; Johansson, K. E.; Boomsma, W.; Stein, A.; Lindorff-Larsen, K.
10.1101/2022.07.14.500157 — biophysics — Posted on 2023-05-02
4262 Variance Analysis of LC-MS Experimental Factors and Their Impact on Machine Learning
Rehfeldt, T. G.; Krawczyk, K.; Echers, S. G.; Marcatili, P.; Palczynski, P.; Roettger, R.; Schwaemmle, V.
10.1101/2023.05.01.538996 — bioinformatics — Posted on 2023-05-02
4267 Imitation performance in primary school children
Ottoboni, G.; Toraldo, A.; Proietti, R.; Cangelosi, A.; Tessari, A.
10.1101/2022.04.27.489190 — animal behavior and cognition — Posted on 2023-05-02
4268 Collagen of ancient bones gives an indication of endogenous DNA preservation based on the next generation sequencing technology
Nakamura, Y.; Waku, D.; Wakiyama, Y.; Watanabe, Y.; Koganebuchi, K.; Nagaoka, T.; Hirata, K.; Ohashi, J.; Takahashi, R.; Yoneda, M.; Oota, H.
10.1101/2023.05.02.538509 — genomics — Posted on 2023-05-02
4270 Duplications of human longevity-associated genes across placental mammals
Huang, Z.; Jiang, C.; Gu, J.; Uvizl, M.; Power, S.; Douglas, D.; Kacprzyk, J.
10.1101/2023.05.02.539026 — evolutionary biology — Posted on 2023-05-02
4271 Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos
Regin, M.; Lei, Y.; De Deckersberg, E. C.; Guns, Y.; Verdyck, P.; Verheyen, G.; Van de Velde, H.; Sermon, K.; Spits, C.
10.1101/2022.08.31.506009 — developmental biology — Posted on 2023-05-02
4273 PACAP-mediated gating of anxiety-controlling circuits
Li, Y.; Andero, R.; Luchkina, N. V.; Suh, J.; Ross, R. A.; Lowell, B. B.; Carlezon, W. A.; Ressler, K. J.; Bolshakov, V.
10.1101/2023.05.01.539007 — neuroscience — Posted on 2023-05-02
4274 Evidence for conservation of a primordial 12-hour ultradian gene program in humans
Zhu, B.; Liu, S.; David, N. L.; Dion, W.; Doshi, N. K.; Siegel, L. B.; Amorim, T.; Andrews, R. E.; Kumar, G. N.; Irfan, S.; Pesaresi, T.; Sharma, A. X.; Sun, M.; Fazeli, P. K.; Steinhauser, M. L.
10.1101/2023.05.02.539021 — systems biology — Posted on 2023-05-02
4276 Phenotypic innovation in one tooth induced concerted developmental evolution in another
Semon, M.; Gueguen, L.; Steklikova, K.; Mouginot, M.; Peltier, M.; Veber, P.; Pantalacci, S.
10.1101/2020.04.22.043422 — evolutionary biology — Posted on 2023-05-02
4281 Unconventional Initiation of PINK1/Parkin Mitophagy by Optineurin
Nguyen, T. N.; Sawa-makarska, J.; Khuu, G.; Lam, W. K.; Adriaenssens, E.; Fracchiolla, D.; Shoebridge, S.; Padman, B. S.; Skulsuppaisarn, M.; Lindblom, R. S. J.; Martens, S.; Lazarou, M.
10.1101/2022.08.14.503930 — cell biology — Posted on 2023-05-02
4282 Sensory Schwann cells set perceptual thresholds for touch and selectively regulate mechanical nociception
Ojeda-Alonso, J.; Calvo-Enrique, L.; Paricio-Montesinos, R.; Kumar, R.; Dong-Zhang, M.; Poulet, J. F. A.; Ernfors, P.; Lewin, G. R.
10.1101/2022.02.04.477749 — neuroscience — Posted on 2023-05-02
4283 Automatic cell type harmonization and integration across Human Cell Atlas datasets
Xu, C.; Prete, M.; Webb, S.; Jardine, L.; Stewart, B.; Hoo, R.; He, P.; Teichmann, S.
10.1101/2023.05.01.538994 — bioinformatics — Posted on 2023-05-01
4284 Rational development of a small-molecule activator of CK1γ2 that decreases C99 and beta-amyloid levels
Bustos, V. H.; Sunkari, Y. K.; Sinha, A.; Pulina, M.; Bispo, A.; Hopkins, M.; Lam, A.; Feinstein, S.; Mui, E.; Chang, E.; Jedlicki, A.; Rosenthal, H.; Flajolet, M.; Greengard, P.; Sinha, S.
10.1101/2023.04.28.538773 — pharmacology and toxicology — Posted on 2023-05-01
4285 Seroprevalence and risk factors associated with brucellosis in goats in Nyagatare district, Rwanda.
Habimana, J. P.; Ntivuguruzwa, J. B.; Uwimana, A. L.; Ugirabe, A.; Gasana, E.; van Heerden, H.
10.1101/2023.05.01.538860 — microbiology — Posted on 2023-05-01
4287 Microsporidia dressing up: the spore polaroplast transport through the polar tube and transformation into the sporoplasm membrane
Lv, Q.; Chen, Y.; Qi, L.; Hong, L.; Xie, Z.; Liao, H.; He, X.; Li, C.; Meng, X.; Chen, J.; Han, B.; Shen, Q.; Weiss, L. M.; Zhou, Z.; Long, M.; Pan, G.
10.1101/2023.05.01.538940 — pathology — Posted on 2023-05-01
4289 Loss of IRF5 increases ribosome biogenesis leading to alterations in mammary gland architecture and metastasis
Brune, Z.; Li, D.; Song, S.; Li, D. I.; Castro, I.; Rasquinha, R.; Rice, M.; Guo, Q.; Kampta, K.; Moss, M.; Lallo, M.; Pimenta, E.; Somerville, C.; Lapan, M.; Nelson, V.; Dos Santos, C.; Blanc, L.; Pruitt, K.; Barnes, B. J. J.
10.1101/2023.05.01.538998 — cancer biology — Posted on 2023-05-01
4290 Probing macromolecular crowding at the lipid membrane interface with genetically-encoded sensors
Loewe, M.; Haensch, S.; Hachani, E.; Schmitt, L.; Weidtkamp-Peters, S.; Kedrov, A.
10.1101/2023.05.01.538982 — biophysics — Posted on 2023-05-01
4291 Increased intracellular crowding during hyperosmotic stress
Kitamura, A.; Oasa, S.; Kawaguchi, H.; Osaka, M.; Vukojevic, V.; Kinjo, M.
10.1101/2022.12.30.522363 — biophysics — Posted on 2023-05-01
4296 WEGS: a cost-effective sequencing method for genetic studies combining high-depth whole exome and low-depth whole genome
Bherer, C.; Eveleigh, R.; Trajanoska, K.; St-Cyr, J.; Paccard, A.; Nadukkalam Ravindran, P.; Caron, E.; Bader Asbah, N.; Wei, C.; Baumgartner, I.; Schindewolf, M.; Döring, Y.; Perley, D.; Lefebvre, F.; Lepage, P.; Bourgey, M.; Bourque, G.; Ragoussis, J.; Mooser, V.; Taliun, D.
10.1101/2023.04.27.538531 — genomics — Posted on 2023-05-01
4298 Phages overcome bacterial immunity via diverse anti-defense proteins
Yirmiya, E.; Leavitt, A.; Lu, A.; Avraham, C.; Osterman, I.; Garb, J.; Antine, S. P.; Mooney, S. E.; Hobbs, S. J.; Kranzusch, P. J.; Amitai, G.; Sorek, R.
10.1101/2023.05.01.538930 — genetics — Posted on 2023-05-01
4301 Synergistic effects of predation and parasitism on competition between edible and inedible phytoplankton
Kasada, M.; Thongthaisong, P.; Wollrab, S.; Van den Wyngaert, S.; Kiel, C.; Berger, S. A.; Grossart, H.-P.
10.1101/2023.05.01.538997 — ecology — Posted on 2023-05-01
4303 GPCR binding and JNK3 activation by arrestin-3 have different structural requirements
Zheng, C.; Weinstein, L. D.; Nguyen, K. K.; Grewal, A.; Gurevich, E. V.; Gurevich, V. V.
10.1101/2023.05.01.538990 — cell biology — Posted on 2023-05-01
4304 Regulation of lipolysis by 14-3-3 proteins on human adipocyte lipid droplets.
Yang, Q.; Yang Loureiro, Z.; Desai, A.; DeSouza, T.; Li, K.; Wang, H.; Nicoloro, S. M.; Solivan-Rivera, J.; Corvera, S.
10.1101/2023.05.01.538914 — cell biology — Posted on 2023-05-01
4307 Lack of detection of SARS-CoV-2 in British wildlife 2020-21 and first description of a stoat (Mustela erminea) Minacovirus
Apaa, T.; Withers, A.; Mckenzie, L.; Staley, C. E.; Blanchard, A. M.; Bennett, M.; Bremner-Harrison, S.; Chadwick, E.; Hailer, F.; Harrison, S.; Lambin, X.; loose, M.; Mathews, F.; Tarlinton, R. E.
10.1101/2023.04.28.538769 — microbiology — Posted on 2023-05-01
4308 Sulfur oxidation and reduction are coupled to nitrogen fixation in the roots of a salt marsh foundation plant species
Rolando, J. L.; Kolton, M.; Song, T.; Liu, Y.; Kostka, J. E.; Pinamang, P.; Conrad, R. E.; Morris, J. T.; Konstantinidis, K. T.
10.1101/2023.05.01.538948 — microbiology — Posted on 2023-05-01
4310 Structural basis of Gabija anti-phage defense and viral immune evasion
Antine, S. P.; Johnson, A. G.; Mooney, S. E.; Leavitt, A.; Mayer, M.; Yirmiya, E.; Amitai, G.; Sorek, R.; Kranzusch, P.
10.1101/2023.05.01.538945 — microbiology — Posted on 2023-05-01
4311 Lupus autoantibodies initiate a maladaptive equilibrium sustained by HMGB1:RAGE signaling and reversed by LAIR-1:C1q signaling
Carroll, K.; Mizrachi, M.; Simmons, S.; Toz, B.; Wingard, J.; Tehrani, N.; Zarfeshani, A.; Kello, N.; Kowal, C.; Levin, J. Z.; Volpe, B.; Diamond, B.
10.1101/2023.05.01.538935 — immunology — Posted on 2023-05-01
4312 SIV clearance from neonatal macaques following transient CCR5 depletion
Deere, J. D.; Merriam, D.; Leggat, K. M.; Lu, W.; Mendez-Lagares, G.; Kieu, H.; Dutra, J.; Fontaine, J.; Lu, W.; Chin, N.; Chen, C.; Tran, B. C.-T.; Salinas, J.; Miller, C. N.; Deeks, S. G.; Lifson, J. D.; Engelman, K.; Magnani, D.; Reimann, K.; Stevenson, M.; Hartigan-O'Connor, D. J.
10.1101/2023.05.01.533682 — immunology — Posted on 2023-05-01
4313 HDAC-6 inhibition ameliorates the early neuropathology in a mouse model of Krabbe disease
Braz, S. O.; Morgado, M. M.; Pereira, M. I.; Monteiro, A. C.; Jarpe, M.; Brites, P.; Sousa, M. M.; Nogueira-Rodrigues, J.
10.1101/2023.05.01.538924 — neuroscience — Posted on 2023-05-01
4318 Characterization of the SARS-CoV-2 BA.5.5 and BQ.1.1 Omicron Variants in Mice and Hamsters
Case, J. B.; Scheaffer, S. M.; Darling, T. L.; Bricker, T. L.; Adams, L. J.; Harastani, H. H.; Trende, R.; Sanapala, S.; Fremont, D. H.; Boon, A. C. M.; Diamond, M. S.
10.1101/2023.04.28.538747 — microbiology — Posted on 2023-05-01
4320 MCell4 with BioNetGen: A Monte Carlo Simulator of Rule-Based Reaction-Diffusion Systems with Python Interface
Husar, A.; Ordyan, M.; Garcia, G. C.; Yancey, J. G.; Saglam, A. S.; Faeder, J.; Bartol, T. M.; Sejnowski, T. J.
10.1101/2022.05.17.492333 — biophysics — Posted on 2023-05-01
4321 Diversity-oriented synthesis encoded by deoxyoligonucleotides
Hudson, L.; Mason, J. W.; Westphal, M. V.; Richter, M. J. R.; Thielman, J. R.; Hua, B. K.; Gerry, C. J.; Xia, G.; Osswald, H. L.; Knapp, J. M.; Tan, Z. Y.; Kokkonda, P.; Tresco, B. I. C.; Liu, S.; Reidenbach, A. G.; Lim, K. S.; Poirier, J.; Capece, J.; Bonazzi, S.; Gampe, C. M.; Smith, N. J.; Bradner, J. E.; Coley, C. W.; Clemons, P. A.; Melillo, B.; Hon, C. S.-Y.; Ottl, J.; Dumelin, C. E.; Schaefer, J. V.; Faust, A. M. E.; Berst, F.; Schreiber, S. L.; Zecri, F. J.; Briner, K.
10.1101/2022.10.16.512431 — biochemistry — Posted on 2023-05-01
4323 Balancing selection at a wing pattern locus is associated with major shifts in genome-wide patterns of diversity and gene flow in a butterfly
Rodriguez de Cara, M. A.; Jay, P.; Rougemont, Q.; Chouteau, M.; Whibley, A.; Huber, B.; Piron-Prunier, F.; Ramos, R. R.; Freitas, A. V. L.; Salazar, C.; Silva-Brandao, K. L.; Torres, T. T.; Joron, M.
10.1101/2021.09.29.462348 — evolutionary biology — Posted on 2023-05-01
4325 TRPM5+ microvillous tuft cells regulate neuroepithelial intrinsic olfactory stem cell proliferation.
Ualiyeva, S.; Lemire, E. R.; Boyd, A.; Wong, C.; Aviles, E. C.; Perniss, A.; Minichetti, D.; Maxfield, A.; Roditi, R.; Barett, N.; Barett, N.; Bucheit, K. M.; Laidlaw, T. M.; Boyce, J. A.; Bankova, L. G.; Haber, A. L.
10.1101/2022.09.26.509561 — immunology — Posted on 2023-05-01
4327 Skeletal Muscle Proteostasis Promotes Central Nervous System Function and Reduces Neuroinflammation during Aging and Neurodegenerative Disease
Matthews, I.; Birnbaum, A.; Gromova, A.; Coutinho, K.; McGraw, M.; Patterson, D.; Banks, M. T.; Nobles, A.; Nguyen, N.; Miranda, H. C.; La Spada, A. R.; Cortes, C. J.
10.1101/2022.03.07.482891 — neuroscience — Posted on 2023-05-01
4329 Rational development of a small-molecule activator of CK1γ2 that decreases C99 and beta-amyloid levels
Bustos, V.; Sunkari, Y.; Sinha, A.; Pulina, M.; Bispo, A.; Hopkins, M.; Lam, A.; Feinstein, S.; Mui, E.; Chang, E.; Jedlicki, A.; Rosenthal, H.; Flajolet, M.; Greengard, P.; Sinha, S.
10.1101/2023.04.28.538773 — pharmacology and toxicology — Posted on 2023-05-01
4330 Complex genotype-phenotype relationships shape the response to treatment of Down Syndrome Childhood Acute Lymphoblastic Leukaemia
Lutz, C.; Turati, V. A.; Clifford, R.; Woll, P. S.; Stiehl, T.; Castor, A.; Clark, S. A.; Ferry, H.; Buckle, V.; Trumpp, A.; Ho, A.; Marciniak-Czochra, A.; Herrero, J.; Schuh, A.; Jacobsen, S. E. W.; Enver, T.
10.1101/2022.02.06.479302 — cancer biology — Posted on 2023-05-01
4333 Molecular early burst associated with the diversification of birds at the K-Pg boundary
Berv, J. S.; Singhal, S.; Field, D. J.; Walker-Hale, N.; McHugh, S. W.; Shipley, J. R.; Miller, E. T.; Kimball, R. T.; Braun, E. L.; Dornburg, A.; Parins-Fukuchi, C. T.; Prum, R. O.; Winger, B. M.; Friedman, M.; Smith, S. A.
10.1101/2022.10.21.513146 — evolutionary biology — Posted on 2023-05-01
4335 Machine learning classification by fitting amplicon sequences to existing OTUs
Armour, C. R.; Sovacool, K. L.; Close, W. L.; Topcuoglu, B. D.; Wiens, J.; Schloss, P. D.
10.1101/2022.09.01.506299 — microbiology — Posted on 2023-05-01
4336 HIV-2 Immature Particle Morphology Provides Insights into Gag Lattice Stability and Virus Maturation
Talledge, N.; Yang, H.; Shi, K.; Coray, R.; Yu, G.; Arndt, W. G.; Meng, S.; Baxter, G. C.; Mendonca, L.; Castano-Dlez, D.; Aihara, H.; Mansky, L. M.; Zhang, W.
10.1101/2022.02.01.478508 — microbiology — Posted on 2023-05-01
4337 Host-cell Interactions of Engineered T cell Micropharmacies
Bourne, C.; Wallisch, P.; Dacek, M.; Gardner, T.; Pierre, S.; Vogt, K.; Corless, B.; Bah, M.; Romero-Pichardo, J.; Charles, A.; Kurtz, K.; Tan, D.; Scheinberg, D. A.
10.1101/2023.04.05.535717 — immunology — Posted on 2023-05-01
4338 Comparison of Anatomical and Diffusion MRI for detecting Parkinson's Disease using Deep Convolutional Neural Network
Chattopadhyay, T.; Singh, A.; Laltoo, E.; Boyle, C. P.; Owens-Walton, C.; Chen, Y.-L.; Cook, P.; McMillan, C.; Tsai, C.-C.; Wang, J.-J.; Wu, Y.-R.; van der Werf, Y.; Thompson, P. M.
10.1101/2023.05.01.538952 — neuroscience — Posted on 2023-05-01
4342 Adrenomedullin promotes interneuron migration in a dual human model for hypoxic interneuronopathy of prematurity.
Michno, W. M.; Puno, A.; Li, L.; Everitt, A.; McCluskey, K.; Birey, F.; Htun, S.; Nagar, D.; Dai, Y.; Gurwitz, E.; Willsey, J.; Pasca, A. M.
10.1101/2023.05.01.538334 — neuroscience — Posted on 2023-05-01
4343 Astrocytic Foxo1 regulates hippocampal spinogenesis and synaptic plasticity to enhance fear memory
Viana, J. F.; Guerra-Gomes, S.; Abreu, D. S.; Machado, J. L.; Barsanti, S.; Goncalves, M.; Martin-Monteagudo, C.; Sardinha, V.; Nascimento, D.; Tavares, G.; Irmler, M.; Beckers, J.; Korostynski, M.; Sousa, N.; Navarrete, M.; Teixeira-Castro, A.; Pinto, L.; Oliveira, J. F.
10.1101/2023.05.01.538923 — neuroscience — Posted on 2023-05-01
4344 Brain-wide Correspondence Between Neuronal Epigenomics and Long-Distance Projections
Zhou, J.; Zhang, Z.; Wu, M.; Liu, H.; Pang, Y.; Bartlett, A.; Rivkin, A. C.; Lagos, W. N.; Williams, E.; Lee, C.-T.; Miyazaki, P. A.; Aldridge, A. I.; Zeng, Q.; Salinda, J. L. A.; Claffey, N.; Liem, M.; Fitzpatrick, C.; Boggeman, L.; Yao, Z.; Smith, K. A.; Tasic, B.; Altshul, J.; Kenworthy, M. A.; Valadon, C.; Nery, J. R.; Castanon, R. G.; Patne, N. S.; Vu, M.; Rashid, M.; Jacobs, M. W.; Ito-Cole, T.; Osteen, J.; Emerson, N.; Lee, J.; Cho, S.; Rink, J.; Huang, H.-H.; Pinto-Duartec, A.; Dominguez, B.; Smith, J. B.; O'Connor, C.; Zeng, H.; Lee, K.-F.; Mukamel, E. A.; Jin, X.; Behrens, M. M.; Eck
10.1101/2023.05.01.538832 — neuroscience — Posted on 2023-05-01
4347 Open-loop lab-on-a-chip technology enables remote computer science training in Latinx life sciences students
Sano, T.; Sampad, M. J. N.; Gonzalez-Ferrer, J.; Hernandez, S.; Vera-Choqqueccota, S.; Vargas, P. A.; Urcuyo, R.; Montellano Duran, N.; Teodorescu, M.; Haussler, D.; Schmidt, H.; Mostajo-Radji, M. A.
10.1101/2023.04.28.538776 — scientific communication and education — Posted on 2023-05-01
4350 High pathogenicity avian influenza (H5N1) in Northern Gannets: Global spread, clinical signs, and demographic consequences
Lane, J. V.; Jeglinski, J. W.; Avery-Gomm, S.; Ballstaedt, E.; Banyard, A. C.; Barychka, T.; Brown, I.; Brugger, B.; Burt, T. V.; Careen, N.; Castenschoid, J. H. F.; Christensen-Dalsgaard, S.; Clifford, S.; Collins, S. M.; Cunningham, E.; Danielsen, J.; Daunt, F.; d'Entremont, K.; Doiron, P.; Duffy, S.; English, M. D.; Falchieri, M.; Giacinti, J.; Gjerset, B.; Granstad, S.; Gremillet, D.; Guillemette, M.; Hallgrimsson, G. T.; Hamer, K. C.; Hammer, S.; Harrison, K.; Hart, J. D.; Hatsell, C.; Humpidge, R.; James, J.; Jenkinson, A.; Jessopp, M.; Jones, M.; Lair, S.; Lewis, T.; Malinowska, A. A.;
10.1101/2023.05.01.538918 — ecology — Posted on 2023-05-01
4353 Meta-analysis and Open-source Database for In Vivo Brain Magnetic Resonance Spectroscopy Studies of Health and Disease
Gudmundson, A. T.; Koo, A.; Virovka, A.; Amirault, A. L.; Soo, M.; Cho, J. H.; Oeltzschner, G. T.; Edden, R. A.; Stark, C. E.
10.1101/2023.02.10.528046 — neuroscience — Posted on 2023-05-01
4355 Glutamate Transporters are Involved in Direct Inhibitory Synaptic Transmission in the Vertebrate Retina
Niklaus, S.; Glasauer, S. M. K.; Kovermann, P.; Farshori, K. F.; Cadetti, L.; Fruh, S.; Rieser, N. N.; Gesemann, M.; Fahkle, C.; Neuhauss, S. C.
10.1101/2023.05.01.538911 — neuroscience — Posted on 2023-05-01
4356 Building flexible and robust analysis frameworks for molecular subtyping of cancers
Pedersen, C. B.; Campos, B.; Krishnan, N. M.; Panda, B.; Vitting-Seerup, K.; Rossing, M. C.; Bagger, F. O.; Olsen, L. R.
10.1101/2023.05.01.538907 — bioinformatics — Posted on 2023-05-01
4360 Orchid seed germination through auto-activation of mycorrhizal symbiosis signaling regulated by gibberellin
Miura, C.; Furui, Y.; Yamamoto, T.; Kanno, Y.; Honjo, M.; Yamaguchi, K.; Suetsugu, K.; Yagame, T.; Seo, M.; Shigenobu, S.; Yamato, M.; Kaminaka, H.
10.1101/2023.04.26.538379 — plant biology — Posted on 2023-05-01
4361 Hemin-driven chromatin remodelling by atherosclerotic risk gene SMARCA4 switches human blood-derived macrophages from leukocyte disposal to erythrocyte disposal
Cave, L.; Lodge, K. M.; Chiappo, D.; Sinha, S.; Chugtai, F.; Tsao, A.; Mason, J. C.; Haskard, D. O. J.; Humphries, S. E.; Boyle, J. J.
10.1101/2023.05.01.538808 — pathology — Posted on 2023-05-01
4362 FET fusion oncoproteins disrupt physiologic DNA repair networks and induce ATR synthetic lethality in cancer
Tulpule, A.; Menon, S.; Breese, M. R.; Lin, Y. P.; Allegakoen, H.; perati, s.; Heslin, A.; Horlbeck, M.; Weissman, J. S.; Sweet-Cordero, A.; Bivona, T.
10.1101/2023.04.30.538578 — cancer biology — Posted on 2023-05-01
4363 An inverse agonist of orphan receptor GPR61 reveals a novel allosteric mechanism
Lees, J. A.; Dias, J. M.; Rajamohan, F.; Fortin, J.-P.; O'Connor, R.; Kong, J. X.; Hughes, E.; Fisher, E. L.; Tuttle, J. B.; Lovett, G.; Kormos, B. L.; Unwalla, R. J.; Zhang, L.; Dechert Schmidt, A.-M.; Zhou, D.; Stevens, K. A.; Fennell, K. F.; Varghese, A. H.; Maxwell, A.; Cote, E. E.; Zhang, Y.; Han, S.
10.1101/2023.05.01.538732 — biophysics — Posted on 2023-05-01
4364 Only three principal components account for inter-embryo variability of the spindle length over time.
Le Cunff, Y.; Chesneau, L.; Pastezeur, S.; Pinson, X.; Soler, N.; Fairbrass, D.; Mercat, B.; Rodriguez Garcia, R.; Alayan, Z.; Abdouni, A.; de Neidhardt, G.; Costes, V.; Anjubault, M.; Bouvrais, H.; Heligon, C.; Pecreaux, J.
10.1101/2023.05.01.538870 — bioinformatics — Posted on 2023-05-01
4365 Camouflaging Endovascular Stents with an Endothelial Coat Using CD31 Domain 1-mimetic Peptides
Senemaud, J.; Skarbek, C.; Song, T.; Pan, Z.; Lefevre, I.; Bianchi, E.; Castier, Y.; Nicoletti, A.; Bureau, C.; Caligiuri, G.
10.1101/2023.05.01.538569 — bioengineering — Posted on 2023-05-01
4367 Structural insights into γH2Ax containing nucleosomes
Panigrahi, R.; Edwards, R.; Islam, M. T.; Lu, J.; Kulepa, A.; Kim, T. H.; Glover, J. N. M.
10.1101/2023.04.30.538894 — biochemistry — Posted on 2023-05-01
4370 Orthogonal CRISPR screens to identify transcriptional and epigenetic regulators of human CD8 T cell function
McCutcheon, S.; Swartz, A.; Brown, M.; Barrera, A.; McRoberts Amador, C.; Siklenka, K.; Humayun, L.; Isaacs, J.; Reddy, T. E.; Nair, S.; Antonia, S.; Gersbach, C. A.
10.1101/2023.05.01.538906 — genomics — Posted on 2023-05-01
4371 Exploring life-long tissue homeostasis through lineage tracing and cell transplantation
Rozenberg, I.; Atlan, T.; Franek, R.; Moses, E.; Oron-Gottesman, A.; Chrzanowski, H.; Harel, I.
10.1101/2023.05.01.538839 — genetics — Posted on 2023-05-01
4376 A human omentum-specific mesothelial-like stromal population inhibits adipogenesis through IGFBP2 secretion
Ferrero, R.; Rainer, P.; Russeil, J.; Zachara, M.; Pezoldt, J.; van Mierlo, G.; Gardeux, V.; Saelens, W.; Alpern, D.; Favre, L.; Mantziari, S.; Zingg, T.; Pitteloud, N.; Suter, M.; Matter, M.; Canto, C.; Deplancke, B.
10.1101/2023.05.01.538871 — cell biology — Posted on 2023-05-01
4379 Molecular and morphological characterisation of four new ancyromonad genera and proposal for an updated taxonomy of the Ancyromonadida
Yubuki, N.; Torruella, G.; Galindo, L. J.; Heiss, A. A.; Ciobanu, M. C.; Shiratori, T.; Ishida, K.-i.; Blaz, J.; Kim, E.; Moreira, D.; Lopez-Garcia, P.; Eme, L.
10.1101/2023.04.29.538795 — microbiology — Posted on 2023-05-01
4381 Multimodal engineering of extracellular vesicles for efficient intracellular protein delivery
Liang, X.; Gupta, D.; Xie, J.; Wonterghem, E. V.; Hoecke, L. V.; Hean, J.; Niu, Z.; Wiklander, O. P. B.; Zheng, W.; Wiklander, R. J.; He, R.; Mamand, D. R.; Bost, J.; Zhou, G.; Zhou, H.; Roudi, S.; Zickler, A. M.; Gorgens, A.; Hagey, D.; de Jong, O. G.; Uy, A. G.; Zong, Y.; Mager, I.; Perez, C. M.; Roberts, T. C.; Vader, P.; Vandenbroucke, R. E.; Nordin, J. Z.; EL Andaloussi, S.
10.1101/2023.04.30.535834 — bioengineering — Posted on 2023-05-01
4382 Convergent adaptation of true crabs (Decapoda: Brachyura) to a gradient of terrestrial environments
Wolfe, J. M.; Ballou, L.; Luque, J.; Watson-Zink, V. M.; Ahyong, S. T.; Barido-Sottani, J.; Chan, T.-Y.; Chu, K. H.; Crandall, K. A.; Daniels, S. R.; Felder, D. L.; Mancke, H.; Martin, J. W.; Ng, P. K. L.; Ortega-Hernandez, J.; Palacios Theil, E.; Pentcheff, N. D.; Robles, R.; Thoma, B. P.; Tsang, L. M.; Wetzer, R.; Windsor, A. M.; Bracken-Grissom, H. D.
10.1101/2022.12.09.519815 — evolutionary biology — Posted on 2023-05-01
4385 CTNS mRNA as a potential treatment for nephropathic cystinosis
Bondue, T.; Berlingerio, S. P.; Siegerist, F.; Sendino-Garvi, E.; Schindler, M.; Cairoli, S.; Goffredo, B. M.; Arcolino, F. O.; Dieker, J.; Janssen, M.; Endlich, N.; Brock, R.; Gijsbers, R.; van den Heuvel, L.; Levtchenko, E.
10.1101/2023.04.28.538106 — genetics — Posted on 2023-05-01
4387 Inhibition of proline-rich-tyrosine kinase 2 restores cardioprotection by remote ischemic preconditioning in type 2 diabetes mellitus
Erkens, R.; Duse, D. A.; Brum, A.; Chadt, A.; Becher, S.; Siragusa, M.; Quast, C.; Muessig, J.; Roden, M.; Cortese-Krott, M.; Lammert, E.; Fleming, I.; Jung, C.; Al-Hasani, H.; Heusch, G.; Kelm, M.
10.1101/2023.04.25.538211 — physiology — Posted on 2023-05-01
4388 Hypoxia-induced circSTT3A maintains Breast Cancer Stem Cell formation by Stabilizing PGK1 protein
Ming, X.; Sun, Y.; Zhou, X.; Qin, Y.; Yang, L.; Wen, S.; Qiu, Y.; Jin, T.; Chen, S.; Tang, R.; Guo, Y.; Mranran, L.
10.1101/2023.04.28.538664 — cancer biology — Posted on 2023-05-01
4392 Ghost admixture in eastern gorillas
Pawar, H.; Rymbekova, A.; Cuadros, S.; Huang, X.; de Manuel, M.; van der Valk, T.; Lobon, I.; Alvarez-Estape, M.; Haber, M.; Dolgova, O.; Han, S.; Esteller-Cucala, P.; Juan, D.; Ayub, Q.; Bautista, R.; Kelley, J. L.; Cornejo, O. E.; Lao, O.; Andres, A. M.; Guschanski, K.; Ssebide, B.; Cranfield, M.; Tyler-Smith, C.; Xue, Y.; Prado-Martinez, J.; Marques-Bonet, T.; Kuhlwilm, M.
10.1101/2022.12.19.521012 — evolutionary biology — Posted on 2023-05-01
4394 Bile acids accumulate norovirus-like particles and enhance binding to and entry into human enteric epithelial cells
Palm, E.; Danskog, K.; Nord, S.; Becker, M.; Tanner, H.; Sandblad, L.; Öhlund, D.; Lenman, A.; Arnberg, N.
10.1101/2023.04.28.538707 — microbiology — Posted on 2023-05-01
4396 Cultivation of Melilotus officinalis as a source of bioactive compounds in association with soil recovery practices
Nogues, I.; Passatore, L.; Bustamante, M. A.; Pallozzi, E.; Luz, J.; Traquete, F.; Ferreira, A. E.; Sousa Silva, M.; Cordeiro, C.
10.1101/2023.04.24.538143 — plant biology — Posted on 2023-05-01
4399 Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma
Finotto, L.; Cole, B.; Giese, W.; Baumann, E.; Claeys, A.; Vanmechelen, M.; Decraene, B.; Derweduwe, M.; Dubroja Lakic, N.; Shankar, G.; Nagathihalli Kantharaju, M.; Albrecht, J. P.; Geudens, I.; Stanchi, F.; Ligon, K. L.; Boeckx, B.; Lambrechts, D.; Harrington, K.; Van Den Bosch, L.; De Vleeschouwer, S.; De Smet, F.; Gerhardt, H.
10.1101/2023.04.27.538517 — cancer biology — Posted on 2023-05-01
4400 Transcriptomic Characterization Reveals Disrupted Medium Spiny Neuron Trajectories in Huntington's Disease and Possible Therapeutic Avenues
Galicia Aquirre, C.; Tshilenge, K.-T.; Battistoni, E.; Lopez-Ramirez, A.; Naphade, S.; Perez, K.; Song, S.; Mooney, S. D.; Melov, S.; Ehrlich, M. E.; Ellerby, L. M.
10.1101/2023.04.30.538872 — neuroscience — Posted on 2023-05-01