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Archive, 2023-04

2 Metagenomic analysis of ecological niche overlap and community collapse in microbiome dynamics
Fujita, H.; Ushio, M.; Suzuki, K.; Abe, M. S.; Yamamichi, M.; Okazaki, Y.; Canarini, A.; Hayashi, I.; Fukushima, K.; Fukuda, S.; Kiers, T.; Toju, H.
10.1101/2023.01.17.524457 — microbiology — Posted on 2023-04-30
3 FEMA: Fast and efficient mixed-effects algorithm for large sample whole-brain imaging data
Parekh, P.; Fan, C. C.; Frei, O.; Palmer, C. E.; Smith, D. M.; Makowski, C.; Iverson, J.; Pecheva, D.; Holland, D.; Loughnan, R.; Nedelec, P.; Thompson, W. K.; Hagler, D.; Andreassen, O.; Jernigan, T. L.; Nichols, T.; Dale, A. M.
10.1101/2021.10.27.466202 — neuroscience — Posted on 2023-04-30
5 A megaprotein brake for aging and insulin-mTOR signaling
Pandey, T.; Wang, B.; Wang, C.; Zu, J.; Deng, H.; Shen, K.; Vale, G.; McDonald, J. G.; Ma, D. K.
10.1101/2023.02.14.528431 — physiology — Posted on 2023-04-30
7 Large genetic variability of maize leaf palatability to european corn borer : metabolic insights
Sanane, I.; Nicolas, S.; Bauland, C.; Marion-Pol, F.; Nous, C.; Legrand, J.; Dillmann, C.
10.1101/2023.04.12.536551 — genetics — Posted on 2023-04-30
14 Plasma membrane association and resistosome formation of plant helper immune receptors
Wang, Z.; Liu, X.; Yu, J.; Yin, S.; Cai, W.-J.; Kim, N. H.; Kasmi, F. E.; Dangl, J. L.; Wan, L.
10.1101/2023.01.23.525201 — plant biology — Posted on 2023-04-30
15 VEGF-C expressing Tumor-Associated Macrophages decrease hematogenous metastatic dissemination and normalizes the tumor vasculature
Ferreira, S. d. S.; Wallmann, T.; Kerzel, T.; Wallerius, M.; Landwehr, L. S.; Agardy, D. A.; Bergh, J.; Bartish, M.; Hartman, J.; Squadrito, M. L.; Rolny, C.
10.1101/2022.01.26.468593 — cancer biology — Posted on 2023-04-30
16 A benchmark study on current GWAS models in admixed populations
Yang, Z.; Huaman, B.; Reyes-Dumeyer, D.; Montesinos, R.; Soto-Anari, M.; Custodio, N.; Tosto, G.
10.1101/2023.04.27.538299 — bioinformatics — Posted on 2023-04-30
17 Branched chain amino acid synthesis is coupled to TOR activation early in the cell cycle in yeast
Blank, H. M.; Reuse, C.; Schmidt-Hohagen, K.; Hammer, S. E.; Hiller, K.; Polymenis, M.
10.1101/2023.01.10.523468 — biochemistry — Posted on 2023-04-30
21 Chemotherapy-induced intestinal injury promotes Galectin-9-driven modulation of T cell function
Coffer, P. J.; Lindemans, C. A.; Cutilli, A.; Jansen, S. A.; de Koning, C. C.; van Hoesel, M.; Nierkens, S.; Mokry, M.; Nieuwenhuis, E. E.; Mocholi, E.; Hanash, A.
10.1101/2023.04.30.538862 — immunology — Posted on 2023-04-30
23 An end-to-end pipeline for succinic acid production at an industrially relevant scale using Issatchenkia orientalis
Tran, V. G.; Mishra, S.; Bhagwat, S. S.; Shafaei, S.; Shen, Y.; Allen, J. L.; Crosly, B. A.; Tan, S.-I.; Fatma, Z.; Rabinowitz, J.; Guest, J. S.; Singh, V.; Zhao, H.
10.1101/2023.04.30.538856 — synthetic biology — Posted on 2023-04-30
31 The LRRK2 kinase substrates Rab8a and Rab10 contribute complementary but distinct disease-relevant phenotypes in human neurons
Mamais, A.; Sanyal, A.; Fajfer, A.; Zykoski, C. G.; Guldin, M.; Riley-DiPaolo, A.; Subrahmanian, N.; Gibbs, W. S.; Lin, S.; LaVoie, M. J.
10.1101/2023.04.30.538317 — neuroscience — Posted on 2023-04-30
32 Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease
Fowler, S. L.; Behr, T. S.; Turkes, E.; Maglio-Cauhy, P.; Foiani, M. S.; Schaler, A.; Crowley, G.; Bez, S.; Ficulle, E.; Tsefou, E.; O'Brien, D. P.; Fischer, R.; Geary, B.; Gaur, P.; Miller, C.; D'Acunzo, P.; Levy, E.; Duff, K. E.; Ryskeldi-Falcon, B.
10.1101/2023.04.30.537820 — neuroscience — Posted on 2023-04-30
36 Bioelectronic Zeitgebers: targeted neuromodulation to re-establish circadian rhythms.
Deli, A.; Zamora, M.; Fleming, J.; Zand, A. P. D.; Benjaber, M.; Green, A. L.; Denison, T.
10.1101/2023.04.30.538861 — bioengineering — Posted on 2023-04-30
43 Development of a nucleoside-modified mRNA vaccine against clade 2.3.4.4b H5 highly pathogenic avian influenza virus
Furey, C.; Ye, N.; Kercher, L.; DeBeauchamp, J.; Crumpton, J. C.; Jeevan, T.; Patton, C.; Franks, J.; Alameh, M.-G.; Fan, S. H. Y.; Phan, A. T.; Hunter, C. A.; Webby, R. J.; Weissman, D.; Hensley, S. E.
10.1101/2023.04.30.538854 — microbiology — Posted on 2023-04-30
44 The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic Trypanosoma brucei infection
Quintana Alcala, J. F.; Sinton, M. C.; Chandrasegaran, P.; Dubey, L. K.; Ogunsola, J.; Samman, M. A.; Haley, M.; McConnell, G.; Kuispond Swar, N. R.; Ngoyi, D. M.; Mabbott, N. A.; MacLeod, A.
10.1101/2023.04.30.538710 — immunology — Posted on 2023-04-30
48 Cell-autonomous BMP signalling plays a key role in the maintenance of tumour cell EMT and migration programs in human ovarian carcinoma
Joun, G.; Zolghadr, F.; Chakraborty, P.; Thi Yen, L. L.; J.H. Chong, J.; Bowtell, D.; DeFazio, A.; Jolly, M. K.; Seyedasli, N.
10.1101/2023.04.30.538847 — cancer biology — Posted on 2023-04-30
49 Serial Lift-Out - Sampling the Molecular Anatomy of Whole Organisms
Schioetz, O. H.; Kaiser, C. J. O.; Klumpe, S.; Morado, D. R.; Poege, M.; Schneider, J.; Beck, F.; Thompson, C.; Plitzko, J. M.
10.1101/2023.04.28.538734 — biophysics — Posted on 2023-04-30
58 Epigenetic fidelity in complex biological systems and implications for ageing
Duffield, T.; Csuka, L.; Akalan, A.; Vega Magdaleno, G.; Palmer, D.; de Magalhaes, J. P.
10.1101/2023.04.29.538716 — genomics — Posted on 2023-04-30
63 SINGLE CELL RESOLUTION SPATIAL MAPPING OF HUMAN HEMATOPOIESIS REVEALS AGING-ASSOCIATED TOPOGRAPHIC REMODELING
Sarachakov, A.; Svekolkin, V.; Varlamova, A.; Galkin, I.; Valencia, I.; Unkenholz, C.; Pannellini, T.; Akaeva, A.; Smirnova, S.; Ovcharov, P.; Polyakova, M.; Tabakov, D.; Postovalova, E.; Sethi, I.; Shin, N.; Bagaev, A.; Itkin, T.; Crane, G.; Kluk, M. J.; Geyer, J.; Inghirami, G.; Patel, S.
10.1101/2023.04.28.538715 — systems biology — Posted on 2023-04-30
66 Segmentation of 3D blood vessel networks using unsupervised deep learning
Sweeney, P. W.; Hacker, L.; Lefebvre, T. L.; Brown, E. L.; Gröhl, J.; Bohndiek, S. E.
10.1101/2023.04.30.538453 — biophysics — Posted on 2023-04-30
67 A novel biomechanical indicator for impaired ankle dorsiflexion function during walking in individuals with chronic stroke
Srivastava, S.; Kindred, J. H.; Seamon, B. A.; Charalambous, C. C.; Boan, A. D.; Kautz, S. A.; Bowden, M. G.
10.1101/2023.04.28.538758 — bioengineering — Posted on 2023-04-30
68 5-hydroxymethylcytosine profiling of cell-free DNA identifies bivalent genes that are prognostic of survival in high-risk neuroblastoma.
Chennakesavalu, M.; Moore, K.; Chaves, G.; Veeravalli, S.; Terhaar, R.; Wu, T.; Lyu, R.; Chlenski, A.; He, C.; Piunti, A.; Applebaum, M. A.
10.1101/2023.04.27.538309 — genomics — Posted on 2023-04-30
69 Emergence of new enhancers at late DNA replicating regions
Cornejo-Paramo, P.; Petrova, V.; Zhang, X.; Young, R.; Wong, E.
10.1101/2022.12.22.521323 — genomics — Posted on 2023-04-30
72 Alternative splicing decouples local from global PRC2 activity
Arecco, N.; Mocavini, I.; Blanco, E.; Ballare, C.; Bonnal, S.; Irimia, M.; Di Croce, L.
10.1101/2023.04.30.538846 — molecular biology — Posted on 2023-04-30
75 A Gold Standard for Transcription Factor-Gene Regulatory Interactions in Escherichia coli K-12: Architecture of the Evidence Types
Lara, P.; Gama-Castro, S.; Salgado, H.; Rioualen, C.; Muniz-Rascado, L. J.; Garcia-Sotelo, J. S.; Tierrafria, V. H.; Collado-Vides, J.
10.1101/2023.02.25.530038 — genomics — Posted on 2023-04-30
80 EGGNet, a generalizable geometric deep learning framework for protein complex pose scoring
Wang, Z.; Brand, R.; Adolf-Bryfogle, J.; Grewal, J.; Qi, Y.; Combs, S. A.; Golovach, N.; Alford, R.; Rangwala, H.; Clark, P. M.
10.1101/2023.03.22.533800 — synthetic biology — Posted on 2023-04-29
82 Genome-scale and pathway engineering for the sustainable aviation fuel precursor isoprenol production in Pseudomonas putida
Banerjee, D.; Yunus, I. S.; Wang, X.; Kim, J.; Srinivasan, A.; Menchavez, R.; Chen, Y.; Gin, J. W.; Petzold, C. J.; Garcia Martin, H.; Adams, P. D.; Mukhopadhyay, A.; Kim, J.; Lee, T. S.
10.1101/2023.04.29.538800 — synthetic biology — Posted on 2023-04-29
85 The outer membrane and peptidoglycan layer form a single mechanical device balancing turgor
Deghelt, M.; Cho, S.-H.; Govers, S. K.; Janssens, A.; Dachsbeck, A.; Remaut, H.; Collet, J.-F.
10.1101/2023.04.29.538579 — microbiology — Posted on 2023-04-29
91 Alveolar repair following lipopolysaccharide-induced injury requires cell-extracellular matrix interactions
Sucre, J. M. S.; Bock, F.; Negretti, N. M.; Benjamin, J. T.; Gulleman, P. M.; Dong, X.; Ferguson, K. T.; Jetter, C. S.; Han, W.; Liu, Y.; Kook, S.; Gokey, J.; Guttentag, S. H.; Kropski, J. A.; Blackwell, T. S.; Zent, R.; Plosa, E. J.
10.1101/2022.08.05.502988 — cell biology — Posted on 2023-04-29
92 A single-cell atlas of the aging murine ovary
Isola, J.; Ocanas, S. R.; Hubbart, C.; Ko, S.; Ali Mondal, S.; Hense, J.; Schneider, A.; Kovats, S.; Freeman, W. M.; Stout, M.
10.1101/2023.04.29.538828 — cell biology — Posted on 2023-04-29
93 iPSC-derived healthy human astrocytes selectively load miRNAs targeting neuronal genes into extracellular vesicles
Gordillo-Sampedro, S.; Antounians, L.; Wei, W.; Mufteev, M.; Lendemeijer, B.; Kushner, S. A.; de Vrij, F.; Zani, A.; Ellis, J.
10.1101/2023.04.29.538761 — molecular biology — Posted on 2023-04-29
96 Cortical parvalbumin neurons are responsible for homeostatic sleep rebound through CaMKII activation
Kon, K.; Ode, K. L.; Mano, T.; Fujishima, H.; Tone, D.; Shimizu, C.; Shiono, S.; Yada, S.; Garcon, J. Y.; Kaneko, M.; Shinohara, Y.; Takahashi, R. R.; Yamada, R. G.; Shi, S.; Sumiyama, K.; Kiyonari, H.; Susaki, E. A.; Ueda, H. R.
10.1101/2023.04.29.537929 — neuroscience — Posted on 2023-04-29
98 Exosomal microRNA signature from plasma-derived extracellular vesicles in gastric cancer
Rincon-Riveros, A.; Quintero Motta, N. S.; Villegas, V. E.; Lopez Kleine, L.; Rodriguez, J. A.
10.1101/2023.04.28.538562 — cancer biology — Posted on 2023-04-29
101 A balance between pro-inflammatory and pro-reparative macrophages is observed in regenerative D-MAPS
Liu, Y.; Suarez-Arnedo, A.; Shetty, S.; Schneider, M.; Collier, J. H.; Segura, T.; Wu, Y.
10.1101/2022.08.17.504283 — bioengineering — Posted on 2023-04-29
106 Descending GABAergic Neurons of the RVM That Mediate Widespread Bilateral Antinociception
Ganley, R. P.; Magalhaes de Sousa, M.; Ranucci, M.; Werder, K.; Öztürk, T.; Wildner, H.; Zeilhofer, H. U.
10.1101/2023.04.29.538824 — neuroscience — Posted on 2023-04-29
112 Pooled effector library screening in protoplasts rapidly identifies novel Avr genes
Arndell, T.; Chen, J.; Sperschneider, J.; Updhyaya, N. M.; Blundell, C.; Niesner, N.; Wang, A.; Swain, S.; Luo, M.; Ayliffe, M. A.; Figueroa, M.; Vanhercke, T.; Dodds, P. N.
10.1101/2023.04.28.538616 — plant biology — Posted on 2023-04-29
115 Identification of B56alpha, B56gamma; and BAP1 as PRR14L binding partners
Chase, A. J.; Carreno-Tarragona, G.; Lin, F.; Yapp, S.; Score, J.; Bryant, C. A.; Cross, N.
10.1101/2023.04.29.538809 — cancer biology — Posted on 2023-04-29
116 Bispecific antibody shuttles targeting CD98hc mediate efficient and long-lived brain delivery of IgGs
Pornnoppadol, G.; Bond, L. G.; Lucas, M. J.; Zupancic, J. M.; Kuo, Y.-H.; Zhang, B.; Greineder, C. F.; Tessier, P. M.
10.1101/2023.04.29.538811 — bioengineering — Posted on 2023-04-29
118 High-throughput functional mapping of variants in an arrhythmia gene, KCNE1, reveals novel biology
Muhammad, A.; Calandranis, M. E.; Li, B.; Yang, T.; Blackwell, D. J.; Harvey, M. L.; Smith, J. E.; Chew, A. E.; Capra, J. A.; Matreyek, K. A.; Fowler, D. M.; Roden, D. M.; Glazer, A. M.
10.1101/2023.04.28.538612 — genomics — Posted on 2023-04-29
123 Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation.
Freitas-Andrade, M.; Comin, C. H.; Van Dyken, P. C.; Ouellette, J.; Raman-Nair, J.; Blakeley, N.; Liu, Q. Y.; Leclerc, S.; Pan, Y.; Liu, Z.; Carrier, M.; Thakur, K.; Savard, A.; Rurak, G. M.; Tremblay, M.-E.; Salmaso, N.; Costa, L. D. F.; Coppola, G.; Lacoste, B.
10.1101/2023.04.29.538807 — developmental biology — Posted on 2023-04-29
126 Rational development of a small-molecule activator of CK1γ2 that decreases C99 and beta-amyloid levels
Bustos, V.; Sunkari, Y.; Sinha, A.; Pulina, M.; Bispo, A.; Hopkins, M.; Lam, A.; Feinstein, S.; Mui, E.; Chang, E.; Jedlicki, A.; Rosenthal, H.; Flajolet, M.; Greengard, P.; Sinha, S.
10.1101/2023.04.28.538773 — pharmacology and toxicology — Posted on 2023-04-29
128 Acetyl transferase EP300 deficiency leads to chronic replication stress mediated by defective fork protection at stalled replication forks
Barreto-Galvez, A.; Niljikar, M.; Gagliardi, J.; Zhang, R.; Juwarwala, A.; Pradeep, A.; Kumar, V.; Tiwari, P.; Shaikh, A.; Sharma, K.; Gerhardt, J.; Cao, J.; Kataoka, K.; Durbin, A.; Qi, J.; Ye, B. H.; Madireddy, A.
10.1101/2023.04.29.538781 — cancer biology — Posted on 2023-04-29
130 Conformational dynamics of the μ-opioid receptor determine ligand intrinsic efficacy
Zhao, J.; Elgeti, M.; O'Brien, E.; Sar, C.; El Daibani, A.; Heng, J.; Sun, X.; Che, T.; Hubbell, W. L.; Kobilka, B.; Chen, C.
10.1101/2023.04.28.538657 — biochemistry — Posted on 2023-04-29
132 The bacterial community of the European spruce bark beetle in space and time
Moussa, A.; Nones, S.; Vannucchi, P. E.; Shahzad, G.-R.; Dittmer, J.; Corretto, E.; Schebeck, M.; Faccoli, M.; Battisti, A.; Stauffer, C.; Schuler, H.
10.1101/2023.04.28.538755 — ecology — Posted on 2023-04-29
133 Stromule geometry allows optimal spatial regulation of organelle interactions in the quasi-2D cytoplasm
Erickson, J.; Prautsch, J.; Reynvoet, F.; Niemeyer, F.; Hause, G.; Johnston, I.; Schattat, M. H.
10.1101/2023.04.27.538610 — plant biology — Posted on 2023-04-29
135 Bacterial colony size growth estimation by deep learning
Nagy, S. A.; Makrai, L.; Csabai, I.; Tozser, D.; Szita, G.; Solymosi, N.
10.1101/2023.04.25.538361 — bioinformatics — Posted on 2023-04-29
137 Seryl-butyrate: a prodrug that enhances butyrate's oral bioavailability and suppresses autoimmune arthritis and experimental autoimmune encephalomyelitis
Cao, S.; Budina, E.; Raczy, M. M.; Solanki, A.; Nguyen, M.; Hultgren, K.; Ang, P.; Reda, J. W.; Shores, L. S.; Pillai, I.; Wallace, R. P.; Dhar, A.; Watkins, E.; Hubbell, J. A.
10.1101/2023.04.28.538720 — bioengineering — Posted on 2023-04-29
144 Expansion of Disease Specific Cardiac Macrophages in Immune Checkpoint Inhibitor Myocarditis
Ma, P.; Liu, J.; Qin, J.; Lai, L.; Heo, G. S.; Luehmann, H.; Sultan, D.; Bredemeyer, A.; Bajpai, G.; Feng, G.; Jimenez, J.; Parks, A.; Amrute, J.; Villanueva, A.; Liu, Y.; Lin, C.-Y.; Mack, M.; Amancherla, K.; Moslehi, J.; Lavine, K.
10.1101/2023.04.28.538426 — immunology — Posted on 2023-04-29
147 Thermoprotection by a cell membrane-localized metacaspase in a green alga
Zou, Y.; Sabljic, I.; Horbach, N.; Dauphinee, A.; Asman, A.; Temino, L. S.; Drag, M.; Stael, S.; Poreba, M.; Stahlberg, J.; Bozhkov, P.
10.1101/2023.04.28.538660 — plant biology — Posted on 2023-04-29
148 Zooarchaeological investigation of the Hoabinhian exploitation of reptiles and amphibians in Thailand and Cambodia with a focus on the Yellow-Headed tortoise (Indotestudo elongata (Blyth, 1854))
Bochaton, C.; Chantasri, S.; Maneechote, M.; Claude, J.; Griggo, C.; Naksri, W.; Forestier, H.; Sophady, H.; Auertrakulvit, P.; Bowonsachoti, J.; Zeitoun, V.
10.1101/2023.04.27.538552 — paleontology — Posted on 2023-04-29
152 Identification of transcription factor co-binding patterns with non-negative matrix factorization
Rauluseviciute, I.; Launay, T.; Barzaghi, G.; Nikumbh, S.; Lenhard, B.; Krebs, A. R.; Castro-Mondragon, J. A.; Mathelier, A.
10.1101/2023.04.28.538684 — bioinformatics — Posted on 2023-04-29
153 The Influence of Brain MRI Defacing Algorithms on Brain-Age Predictions via 3D Convolutional Neural Networks
Cali, R. J.; Bhatt, R.; Thomopoulos, S. I.; Gadewar, S.; Gari, I. B.; Chattopadhyay, T.; Jahanshad, N.; Thompson, P.
10.1101/2023.04.28.538724 — bioinformatics — Posted on 2023-04-29
154 CTNS mRNA as a potential treatment for nephropathic cystinosis
Bondue, T.; Berlingerio, S. P.; Siegerist, F.; Sendino-Garvi, E.; Schindler, M.; Cairoli, S.; Goffredo, B. M.; Arcolino, F. O.; Dieker, J.; Janssen, M.; Endlich, N.; Brock, R.; Gijsbers, R.; van den Heuvel, L.; Levtchenko, E.
10.1101/2023.04.28.538106 — genetics — Posted on 2023-04-29
155 Temperature and day length drive local adaptation in the Patagonian foundation tree species Nothofagus pumilio
Sekely, J. T.; Marchelli, P.; Arana, M. V.; Dauphin, B.; Mattera, M. G.; Pastorino, M. J.; Scotti, I.; Soliani, C.; Heer, K.; Opgenoorth, L.
10.1101/2023.04.28.538677 — genetics — Posted on 2023-04-29
158 The dynamic interaction between predator and prey drives mesopredator movement and foraging ecology
Florko, K. R.; Ross, T. R.; Ferguson, S. H.; Northrup, J. M.; Obbard, M. E.; Thiemann, G. W.; Yurkowski, D. J.; Auger-Methe, M.
10.1101/2023.04.27.538582 — ecology — Posted on 2023-04-29
159 Collecting-Gathering Biophysics of the Blackworm L. variegatus
Tuazon, H.; Nguyen, C.; Kaufman, E.; Tiwari, I.; Bermudez, J.; Chudasama, D.; Peleg, O.; Bhamla, M. S.
10.1101/2023.04.28.538726 — ecology — Posted on 2023-04-29
161 Rare SH2B3 coding variants identified in lupus patients impair B cell tolerance and predispose to autoimmunity
Zhang, Y.; Morris, R.; Lorenzo, A. M. D.; Meng, X.; Kershaw, N. J.; Kiridena, P.; Brown, G. J.; Burgio, G.; Cappello, J. Y.; Shen, Q.; Wang, H.; Turnbull, C. M.; Lea-Henry, T.; Stanley, M.; Yu, Z.; Ballard, F.; Chuah, A.; Lee, J. C.; Hatch, A.-M.; Headley, A. P.; Trnka, P.; Mallon, D.; Fletcher, J. T.; Walters, G. D.; Sestan, M.; Jelusic, M.; Cook, M. C.; Athanasopoulos, V.; Fulcher, D. A.; Babon, J. J.; Vinuesa, C. G.; Ellyard, J. I.
10.1101/2023.04.27.538529 — immunology — Posted on 2023-04-29
163 Post-translational modification of SPATULA by SECRET AGENT and SPINDLY promotes organ symmetry transition at the gynoecium apex
Jiang, Y.; Curran-French, S.; Koh, S. W. H.; Jamil, I.; Argiro, L.; Lopez, S.; Martins, C.; Saalbach, G.; Moubayidin, L.
10.1101/2023.04.28.538690 — plant biology — Posted on 2023-04-29
167 Vessel normalization and maturation promotes nanoparticle delivery to solid tumors while minimizing metastases.
Izci, M.; Maksoudian, C.; Goncalves, F.; Chu, T.; Rios Luci, C.; Bolea Fernandez, E.; Vanhaecke, F.; Manshian, B. B.; Soenen, S. J.
10.1101/2023.04.27.538559 — pharmacology and toxicology — Posted on 2023-04-29
168 Paracetamol/acetaminophen hepatotoxicity: new markers for monitoring the elimination of the reactive N-Acetyl-p-benzoquinone imine
Gorrochategui, E.; Le Vee, M.; Selmi, H.; Gerard, A.; Chaker, J.; Krais, A. M.; Lindh, C.; Fardel, O.; Chevrier, C.; Le Cann, P.; Miller, G. W.; Barouki, R.; Jegou, B.; Gicquel, T.; Kristensen, D.; David, A.
10.1101/2023.04.28.538718 — pharmacology and toxicology — Posted on 2023-04-29
169 An RNA Damage Response Network Mediates the Lethality of 5-FU in Clinically Relevant Tumor Types
Chen, J.-K.; Merrick, K. A.; Kong, Y. W.; Izrael-Tomasevic, A.; Eng, G.; Handly, E. D.; Patterson, J. C.; Suarez-Lopez, L.; Hosios, A. M.; Dinh, A.; Kirkpatrick, D. S.; Yu, K.; Rose, C. M.; Hernandez, J. M.; Hwangbo, H.; Palmer, A. C.; Vander Heiden, M.; Yilmaz, O. H.; Yaffe, M. B.
10.1101/2023.04.28.538590 — cancer biology — Posted on 2023-04-29
170 Neoepitope-specific vaccination of a patient with diffuse midline glioma targeting H3K27M induces polyclonal B and T cell responses across diverse HLA alleles
Boschert, T.; Kromer, K.; Lerner, T.; Lindner, K.; Haltenhof, G.; Tan, C. L.; Jahne, K.; Poschke, I.; Bunse, L.; Grassl, N.; Mildenberger, I.; Sahm, K.; Platten, M.; Lindner, J. M.; Green, E. W.
10.1101/2023.04.28.538672 — cancer biology — Posted on 2023-04-29
171 Targeted spectroscopy in the eye fundus
Lapointe, N.; Akitegetse, C.; Poirier, J.; Picard, M.; Sauvageau, P.; Sauvageau, D.
10.1101/2023.04.27.538643 — biophysics — Posted on 2023-04-29
172 Magnetic resonance biomarkers for timely diagnostic of radiation dose-rate effects
Zagrean-Tuza, C.; Suditu, M.; Popescu, R.; Bacalum, M.; Negut, D.; Vasilca, S.; Hanganu, A. M.; Fidel, I.; Serafin, D.; Tesileanu, O.; Chiricuta, I. C.; Sadet, A.; Voda, A. M.; Vasos, P.
10.1101/2023.04.28.538667 — biophysics — Posted on 2023-04-29
178 Development of two mouse strains conditionally expressing bright luciferases with distinct emission spectra as new tools for in vivo imaging
Nakashiba, T.; Ogoh, K.; Iwano, S.; Sugiyama, T.; Iijima-Mizuno, S.; Nakashima, K.; Mizuno, S.; Sugiyama, F.; Yoshiki, A.; Miyawaki, A.; Abe, K.
10.1101/2023.04.28.538499 — bioengineering — Posted on 2023-04-29
184 Genetic context controls early microglia-synaptic interactions in mouse models of Alzheimers disease
Heuer, S. E.; Keezer, K. J.; Hewes, A. A.; Onos, K. D.; Graham, K. C.; Howell, G. R.; Bloss, E. B.
10.1101/2023.04.28.538728 — neuroscience — Posted on 2023-04-29
185 Behavioral strategy shapes activation of the Vip-Sst disinhibitory circuit in visual cortex
Piet, A.; Ponvert, N.; Ollerenshaw, D.; Garrett, M.; Groblewski, P. A.; Olsen, S.; Koch, C.; Arkhipov, A.
10.1101/2023.04.28.538575 — neuroscience — Posted on 2023-04-29
186 Neural Signatures of Evidence Accumulation Encode Subjective Perceptual Confidence
Dou, W.; Martinez Arango, L. J.; Castaneda, O. G.; Arellano, L.; Mcintyre, E.; Yballa, C.; Samaha, J.
10.1101/2023.04.28.538782 — neuroscience — Posted on 2023-04-29
187 The adhesion GPCR Adgrd1 is a prion protein receptor and a mediator of prion cytotoxicity
Lakkaraju, A. K.; Tejero, O.; Guixa-Gonzalez, R.; De Cecco, E.; Jungo, M.; Tsai, C.-J.; Mastromartino, R.; Marino, J.; Deupi, X.; Hornemann, S.; Schertler, G. F. X.; Aguzzi, A.
10.1101/2023.04.29.538801 — neuroscience — Posted on 2023-04-29
188 Longitudinal brain structure changes in Parkinson's disease: a replication study
Sokolowski, A.; Bhagwat, N.; Chatelain, Y.; Dugre, M.; Hanganu, A.; Monchi, O.; McPherson, B.; Wang, M.; Poline, J.-B.; Sharp, M.; Glatard, T.
10.1101/2023.04.28.538743 — neuroscience — Posted on 2023-04-29
189 Microbes as part of ancestral neuronal circuits: Bacterial produced signals affect neurons controlling eating behavior in Hydra
Giez, C.; Pinkle, D.; Giencke, Y.; Wittlieb, J.; Herbst, E.; Spratte, T.; Lachnit, T.; Klimovich, A.; Selhuber-Unkel, C.; Bosch, T. C. G.
10.1101/2023.04.28.538719 — animal behavior and cognition — Posted on 2023-04-29
190 Hyper-Cryptic Radiation of a Tropical Montane Plant Lineage
Olivares, I.; Tusso, S.; Sanin, M. J.; Kessler, M.; Shimizu, K. K.
10.1101/2023.04.26.538369 — evolutionary biology — Posted on 2023-04-29
194 Do try this at home: Age prediction from sleep and meditation with large-scale low-cost mobile EEG
Banville, H.; Abou Jaoude, M.; Wood, S. U. N.; Aimone, C.; Holst, S. C.; Gramfort, A.; Engemann, D.-A.
10.1101/2023.04.29.538328 — neuroscience — Posted on 2023-04-29
201 Mechanism of ozone alleviation of malignant ascites in hepatocellular carcinoma through inhibition of NETs
Han, F.; Mu, C. M.; Bian, K.; Mu, Z.; Duan, Q.; Guo, J. Y.; Ma, J.; Jin, L.; Liu, W.; Chen, F.
10.1101/2023.04.26.538380 — cancer biology — Posted on 2023-04-29
203 APOE-NOTCH Axis Governs Elastogenesis During Human Cardiac Valve Remodeling
Liu, Z.; Liu, Y.; Yu, Z.; Pek, N.; ODonnell, A.; Glass, I.; Winlaw, D. S.; Guo, M.; Chen, Y.-W.; Wu, J. C.; Yutzey, K. E.; Miao, Y.; Gu, M.
10.1101/2023.04.26.538443 — bioinformatics — Posted on 2023-04-29
206 Integrated analysis of spatial multi-omics with SpatialGlue
Long, Y.; Ang, K. S.; Liao, S.; Sethi, R.; Heng, Y.; Zhong, C.; Xu, H.; Husna, N.; Jian, M.; Ng, L. G.; Chen, A.; Gascoigne, N. R.; Xu, X.; Chen, J.
10.1101/2023.04.26.538404 — bioinformatics — Posted on 2023-04-29
208 Gene Expression and Splicing QTL Analysis of Blood Cells in African American Participants from the Jackson Heart Study
Wen, J.; Sun, Q.; Huang, L.; Zhou, L.; Doyle, M. F.; Ekunwe, L.; Olson, N. C.; Reiner, A. P.; Li, Y.; Raffield, L. M.
10.1101/2023.04.26.538455 — genetics — Posted on 2023-04-29
212 Characterization of the small Arabidopsis thaliana GTPase and ADP-ribosylation factor-like 2 protein TITAN5
Mohr, I.; Mirzaiebadizi, A.; Sanyal, S.; Chuenban, P.; Ahmadian, M. R.; Ivanov, R.; Bauer, P.
10.1101/2023.04.27.538563 — plant biology — Posted on 2023-04-29
213 Small ADP-ribosylation factor-like GTPase TITAN5 (TTN5/ARL2) is linked with the dynamic regulation of IRON-REGULATED TRANSPORTER1
Mohr, I.; Eutebach, M.; Schommen, N.; Gratz, R.; Angrand, K.; Genders, L.; Brumbarova, T.; Bauer, P.; Ivanov, R.
10.1101/2023.04.27.538571 — plant biology — Posted on 2023-04-29
214 A Zika virus protein expression screen in Drosophila to investigate targeted host pathways during development
Link, N.; Harnish, J. M.; Hull, B.; Gibson, S.; Dietze, M.; Mgbike, U. E.; Medina-Balcazar, S.; Shah, P. S.; Yamamoto, S.
10.1101/2023.04.28.538736 — developmental biology — Posted on 2023-04-29
215 APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size
Windham, I. A.; Ragusa, J. V.; Wallace, E. D.; Wagner, C. H.; White, K. K.; Cohen, S.
10.1101/2023.04.28.538740 — cell biology — Posted on 2023-04-29
216 Endothelial cells secrete small extracellular vesicles bidirectionally containing distinct cargo to uniquely reprogram vascular cells in the circulation and vessel wall
Raju, S.; Botts, S. R.; Blaser, M. C.; Prajapati, K.; Ho, T. W. W.; Ching, C.; Galant, N. J.; Fiddes, L.; Wu, R.; Clift, C. L.; Pham, T.; Lee, W. L.; Singh, S. A.; Aikawa, E.; Fish, J. E.; Howe, K. L.
10.1101/2023.04.28.538787 — cell biology — Posted on 2023-04-29
218 Base editing strategies to convert CAG to CAA diminish the disease-causing mutation in Huntington's disease
Choi, D. E.; Shin, J. W.; Zeng, S.; Hong, E. P.; Jang, J.-H.; Loupe, J. M.; Wheeler, V. C.; Stutzman, H. E.; Kleinstiver, B. P.; Lee, J.-M.
10.1101/2023.04.28.538700 — genetics — Posted on 2023-04-28
223 A manifold neural population code for space in hippocampal coactivity dynamics independent of place fields
Levy, E. R. J.; Carrillo-Segura, S.; Redman, W. T.; Park, E. H.; Hurtado, J.; Fenton, A. A.
10.1101/2021.07.26.453856 — neuroscience — Posted on 2023-04-28
225 A transposase-derived gene required for human brain development
Jubierre Zapater, L.; Rodriguez Fos, E.; Planas-Felix, M.; Lewis, S.; Cameron, D.; Demarest, P.; Nabila, A.; Zhao, J.; Bergin, P.; Reed, C.; Yamada, M.; Socci, N.; Hayes, M.; Rabadan, R.; Torrents, D.; Kruer, M. C.; Toth, M.; Kentsis, A.
10.1101/2023.04.28.538770 — neuroscience — Posted on 2023-04-28
230 Myelodysplastic syndromes disable human CD271+VCAM1+CD146+ niches supporting normal hematopoietic stem/progenitor cells
kawano, Y.; Kawano, H.; Ghoneim, D.; Fountaine, T. J.; Byun, D. K.; LaMere, M. W.; Mendler, J. H.; Ho, T.-C.; Salama, N. A.; Myers, J. R.; Hussein, S. E.; Frisch, B. J.; Ashton, J. M.; Azadniv, M.; Liesveld, J. L.; Kfoury, Y.; Scadden, D. T.; Becker, M. W.; Calvi, L. M.
10.1101/2023.04.09.536176 — cancer biology — Posted on 2023-04-28
232 Optogenetic dissection of transcriptional repression in a multicellular organism
Zhao, J.; Lammers, N. C.; Alamos, S.; Kim, Y. J.; Martini, G.; Garcia, H. G.
10.1101/2022.11.20.517211 — biophysics — Posted on 2023-04-28
233 NIAGADS Alzheimer's GenomicsDB: A resource for exploring Alzheimer's Disease genetic and genomic knowledge
Greenfest-Allen, E.; Valladares, O.; Kuksa, P.; Gangadharan, P.; Lee, W.-P.; Cifello, J.; Katanic, Z.; Kuzma, A.; Wheeler, N.; Bush, W. S.; Leung, Y. Y.; Schellenberg, G.; Stoeckert, C. J.; Wang, L.-S.
10.1101/2020.09.23.310276 — bioinformatics — Posted on 2023-04-28
238 Nano-structured Hydrotrope-Caged Cytochrome c with Boosted Stability in Harsh Environments: A Molecular Insight
Bharadwaj, P.; Sarkar, D. K.; Bisht, M.; Shet, S. M.; Nataraj, S. K.; Lokesh, V.; Franklin, G.; Brezovsky, J.; Mondal, D.
10.1101/2023.02.05.527166 — biochemistry — Posted on 2023-04-28
240 Identification of two novel heterodimeric ABC transporters in melanoma: ABCB5β/B6 and ABCB5β/B9
Gerard, L.; Duvivier, L.; Fourrez, M.; Salazar, P.; Sprimont, L.; Xia, D.; Ambudkar, S. V.; Gottesman, M. M.; Gillet, J.-P.
10.1101/2022.10.21.513191 — biochemistry — Posted on 2023-04-28
241 A high-quality pseudo-phased genome for Melaleuca quinquenervia shows allelic diversity of NLR-type resistance genes
Chen, S. H.; Martino, A. M.; Luo, Z.; Schwessinger, B.; Jones, A.; Tolessa, T.; Bragg, J. G.; Tobias, P. A.; Edwards, R. J.
10.1101/2023.04.27.538497 — genomics — Posted on 2023-04-28
242 Targeted genomic sequencing of avian influenza viruses in wetlands sediment from wild bird habitats
Kuchinski, K.; Coombe, M.; Mansour, S. C.; Cortez, G. A. P.; Kalhor, M.; Himsworth, C. G.; Prystajecky, N. A.
10.1101/2023.03.30.534984 — genomics — Posted on 2023-04-28
243 An allelic series rare variant association test for candidate gene discovery
McCaw, Z. R.; O'Dushlaine, C.; Somineni, H.; Bereket, M.; Klein, C.; Karaletsos, T.; Casale, F. P.; Koller, D.; Soare, T. W.
10.1101/2022.12.23.521658 — genetics — Posted on 2023-04-28
245 Incomplete dosage balance and dosage compensation in the ZZ/ZW Gila monster (Heloderma suspectum) revealed by de novo genome assembly
Webster, T. H.; Vannan, A.; Pinto, B. J.; Denbrock, G.; Morales, M.; Dolby, G. A.; Fiddes, I. T.; DeNardo, D. F.; Wilson, M. A.
10.1101/2023.04.26.538436 — evolutionary biology — Posted on 2023-04-28
247 Transcriptomic profiling of tissue environments critical for post-embryonic patterning and morphogenesis of zebrafish skin
Aman, A. J.; Saunders, L. M.; Carr, A. A.; Srivatsan, S. R.; Eberhard, C.; Carrington, B.; Watkins-Chow, D. E.; Pavan, W.; Trapnell, C.; Parichy, D. M.
10.1101/2021.05.12.443782 — developmental biology — Posted on 2023-04-28
248 Ciliary ARL13B inhibits developmental kidney cystogenesis in mouse
Van Sciver, R. E.; Long, A. B.; Katz, H. G.; Gigante, E. D.; Caspary, T.
10.1101/2023.02.08.527739 — developmental biology — Posted on 2023-04-28
252 Knockout of GMC-oxidoreductase genes reveals functional redundancy in mimivirus
Alempic, J.-M.; Bisio, H.; Villalta, A.; Santini, S.; Lartigue, A.; Schmitt, A.; Bugnot, C.; Notaro, A.; BELMUDES, L.; Adrait, A.; Poirot, O.; Ptchelkine, D.; De Castro, C.; Coute, Y.; Abergel, C.
10.1101/2023.04.28.538727 — microbiology — Posted on 2023-04-28
253 Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasome
Kroken, A. R.; Klein, K. A.; Mitchell, P. S.; Nieto, V.; Jedel, E. J.; Evans, D. J.; Fleiszig, S. M. J.
10.1101/2023.02.13.528260 — microbiology — Posted on 2023-04-28
254 Variability and Bias in Microbiome Metagenomic Sequencing: an Interlaboratory Study Comparing Experimental Protocols
Forry, S. P.; Servetas, S. L.; Kralj, J. G.; Soh, K.; Hadjithomas, M.; Carlin, M.; de Amorim, M. G.; Bartelli, T. F.; Bustamante, J. P.; Cassol, I.; Chalita, M.; Dias-Neto, E.; Gohl, D.; Kazantseva, J.; Menzel, P.; Moda, B. S.; Neuberger-Castillo, L.; Nunes, D.; Peralta, R. D.; Saliou, A.; Schwarzer, R.; Takenaka, I. K. T. M.; Wang, J.; Knight, R.; Jackson, S. A.
10.1101/2023.04.28.538741 — microbiology — Posted on 2023-04-28
255 Antibody landscape of C57BL/6 mice cured of B78 melanoma via immunotherapy
Hoefges, A.; McIlwain, S. J.; Erbe, A. K.; Mathers, N. N.; Xu, A. E.; Melby, D.; Tetreault, K.; Le, T. Q.; Kim, K.; Pinapati, R. S.; Garcia, B.; Patel, J.; Heck, M.; Feils, A.; Tsarovsky, N.; Hank, J. A.; Morris, Z. S.; Ong, I. M.; Sondel, P. M.
10.1101/2023.02.24.529012 — immunology — Posted on 2023-04-28
256 The influence of environment geometry on subiculum boundary vector cells in adulthood and early development
Muessig, L.; Ribeiro Rodrigues, F.; Bjerknes, T.; Towse, B.; Barry, C.; Burgess, N.; Moser, E. I.; Moser, M.-B.; Cacucci, F.; Wills, T. J.
10.1101/2023.04.13.536690 — neuroscience — Posted on 2023-04-28
259 VIP interneurons regulate cortical size tuning and visual perception
Ferguson, K. A.; Salameh, J.; Alba, C.; Selwyn, H.; Barnes, C.; Lohani, S.; Cardin, J. A.
10.1101/2023.03.14.532664 — neuroscience — Posted on 2023-04-28
262 Multivariate models of animal sex: breaking binaries leads to a better understanding of ecology and evolution
McLaughlin, J. F.; Brock, K. M.; Gates, I.; Pethkar, A.; Piattoni, M.; Rossi, A.; Lipshutz, S.
10.1101/2023.01.26.525769 — zoology — Posted on 2023-04-28
263 Translation in a Box: Orthogonal Evolution in the Saccharomyces cerevisiae Mitochondrion
Rothschild-Mancinelli, B.; Alvarez-Carreno, C.; Guo, W.; Ito, C.; Costa, A.; Petrov, A. S.; Lobachev, K.; Williams, L. D.
10.1101/2023.04.28.538752 — synthetic biology — Posted on 2023-04-28
264 scRNA-seq analysis of colon and esophageal tumors uncovers abundant microbial reads in myeloid cells undergoing proinflammatory transcriptional alterations
Robinson, W.; Stone, J. K.; Schischlik, F.; Gasmi, B.; Kelly, M. C.; Seibert, C.; Dadkhah, K.; Gertz, E. M.; Lee, J. S.; Zhu, K.; Ma, L.; Wang, X. W.; Sahinalp, C.; Patro, R.; Leiserson, M. D.; Harris, C. C.; Schäffer, A. A.; Ruppin, E.
10.1101/2020.05.14.096230 — cancer biology — Posted on 2023-04-28
267 Role of the NO-GC/cGMP signaling pathway in platelet biomechanics
Rodriguez, J. G.; Balmes, A.; Seifert, J.; Pinto-Quintero, D.; Khawaja, A. A.; Boffito, M.; Frye, M.; Friebe, A.; Emerson, M.; Seta, F.; Feil, R.; Feil, S.; Schaffer, T. E.
10.1101/2023.04.28.538670 — biochemistry — Posted on 2023-04-28
268 Exposure to childhood maltreatment is associated with changes in sperm small non-coding RNA and DNA methylation profiles
Tuulari, J. J.; Bourgery, M.; Ahonen, A.; Ahmedani, A.; Iversen, J.; Koefoed, T. G.; Kataja, E.-L.; Karlsson, L.; Barres, R.; Karlsson, H.; Kotaja, N.
10.1101/2023.04.27.538231 — molecular biology — Posted on 2023-04-28
269 Meat without vegetables: An ancient ecotype of Helicobacter pylori found in Indigenous populations and animal adapted lineages.
Tourrette, E.; Torres, R. C.; Svensson, S. L.; Matsumoto, T.; Fauzia, K. A.; Alfaray, R. I.; Vilaichone, R.-K.; Tuan, V. P.; HelicobacterGenomicsConsortium, ; Yadegar, A.; Olsson, L.; Zhou, Z.; Yamaoka, Y.; Thorell, K.; Falush, D.
10.1101/2023.04.28.538659 — microbiology — Posted on 2023-04-28
280 Proteomic analysis of peripheral nerve myelin during murine aging
Helbing, D. L.; Kirkpatrick, J. M.; Reuter, M.; Bischoff, J.; Stockdale, A. C.; Carlstedt, A.; Cirri, E.; Bauer, R.; Morrison, H.
10.1101/2023.04.26.538413 — neuroscience — Posted on 2023-04-28
281 Brain2GAN: Feature-disentangled neural coding of visual perception in the primate brain
Dado, T.; Papale, P.; Lozano, A.; Le, L.; Wang, F.; van Gerven, M.; Roelfsema, P.; Güclütürk, Y.; Güclü, U.
10.1101/2023.04.26.537962 — neuroscience — Posted on 2023-04-28
287 KOunt - A reproducible KEGG orthologue abundance workflow
Mattock, J.; Martinez-Alvaro, M.; Cleveland, M. A.; Roehe, R.; Watson, M.
10.1101/2023.04.27.538265 — bioinformatics — Posted on 2023-04-28
290 BRCA2-HSF2BP Oligomeric Ring Disassembly by BRME1 Promotes Homologous Recombination
Ghouil, R.; Miron, S.; Sato, K.; Ristic, D.; van Rossum-Fikkert, S. E.; Legrand, P.; Ouldali, M.; Winter, J.-M.; Ropars, V.; David, G.; Arteni, A.-A.; Wyman, C.; Knipscheer, P.; Kanaar, R.; Zelensky, A. N.; Zinn-Justin, S.
10.1101/2023.04.27.538421 — biochemistry — Posted on 2023-04-28
291 Meiotic recombination dynamics in plants with repeat-based holocentromeres shed light on the primary drivers of crossover patterning
Castellani, M.; Zhang, M.; Thangavel, G.; Mata Sucre, Y.; Campoy, J. A.; Lux, T.; Marek, M.; Huettel, B.; Sun, H.; Mayer, K. F. X.; Schneeberger, K.; Marques, A.
10.1101/2023.04.28.538594 — genomics — Posted on 2023-04-28
292 5-hydroxymethylcytosine profiling of cell-free DNA identifies bivalent genes that are prognostic of survival in high-risk neuroblastoma.
Chennakesavalu, M.; Moore, K.; Chaves, G.; Veeravalli, S.; Terhaar, R.; Wu, T.; Lyu, R.; Chlenski, A.; He, C.; Piunti, A.; Applebaum, M. A.
10.1101/2023.04.27.538309 — genomics — Posted on 2023-04-28
294 Integrated Spatial Transcriptomic and Proteomic Analysis of Fresh Frozen Tissue Based on Stereo-seq
Liao, S.; Heng, Y.; Liu, W.; Xiang, J.; Ma, Y.; Chen, L.; Feng, X.; Jia, D.; Liang, D.; Huang, C.; Zhang, J.; Jian, M.; Su, K.; Li, M.; Loh, Y. H.; Chen, A.; Xu, X.
10.1101/2023.04.28.538364 — molecular biology — Posted on 2023-04-28
296 Prophage acquisition by Staphylococcus aureus contributes to the expansion of Staphylococcal immune evasion
Nepal, R.; Houtak, G.; Bouras, G.; Ramezanpour, M.; Feizi, S.; Shaghayegh, G.; Shearwin, K.; Psaltis, A. J.; Wormald, P.-J.; Vreugde, S.
10.1101/2023.04.27.538627 — microbiology — Posted on 2023-04-28
298 Connectome embedding in multidimensional graph-invariant spaces
Mach, M.; Amico, E.; Liegeois, R.; Preti, M. G.; Griffa, A.; Van De Ville, D.; Pedersen, M.
10.1101/2023.04.25.538320 — neuroscience — Posted on 2023-04-28
299 Synthetic neuromelanin as a trigger of inflammation in the brain, new mouse model of Parkinson's disease
Tejchman-Skrzyszewska, A.; Strzelec, M.; Kot, M.; Chlebanowska, P.; Badyra, B.; Sobocinska, M.; Zecca, L.; Majka, M.
10.1101/2023.04.28.538536 — neuroscience — Posted on 2023-04-28
300 A Ray of Light Against Age Related Neurodegeneration
Fear, E. J.; Kennerey, A. J.; Chen, K.-J.; Scott, M.; Jeffery, G.; Torkelsen, F. H.; Baseler, H.
10.1101/2023.04.25.538307 — neuroscience — Posted on 2023-04-28
305 Plasma-free samples for transcriptomic analysis: a potential alternative to whole blood samples
Chen, Q.; Guo, X.; Wang, H.; Sun, S.; Jiang, H.; Zhang, P.; Shang, E.; Zhang, R.; Cao, Z.; Niu, Q.; Zhang, C.; Liu, Y.; Zheng, Y.; Yu, Y.; Hou, W.; Shi, L.
10.1101/2023.04.27.538178 — bioinformatics — Posted on 2023-04-28
306 A benchmark study on current GWAS models in admixed populations
Yang, Z.; Huaman, B.; Reyes-Dumeyer, D.; Montesinos, R.; Soto-Anari, M.; Custodio, N.; Tosto, G.
10.1101/2023.04.27.538299 — bioinformatics — Posted on 2023-04-28
309 False discovery rates of qpAdm-based screens for genetic admixture
Yüncü, E.; Isıldak, U.; Williams, M. P.; Huber, C. D.; Vyazov, L. A.; Changmai, P.; Flegontov, P.
10.1101/2023.04.25.538339 — genetics — Posted on 2023-04-28
313 Long-Term Oral Tamoxifen Administration Decreases Brain Derived Neurotrophic Factor in the Hippocampus of Female Long-Evans Rats
Been, L. E.; Halliday, A. R.; Blossom, S. M.; Bien, E. M.; Bernhard, A. G.; Roth, G. E.; Domenech Rosario, K. I.; Pollock, K. B.; Abramenko, P. E.; Behbehani, L. M.; Pascal, G. J.; Kelly, M. E.
10.1101/2023.04.26.538155 — neuroscience — Posted on 2023-04-28
316 Sensorimotor Confidence for Tracking Eye Movements
Goettker, A.; Locke, S. M.; Gegenfurtner, K. R.; Mamassian, P.
10.1101/2023.04.28.538675 — neuroscience — Posted on 2023-04-28
317 Removal of a genomic duplication by double-nicking CRISPR restores synaptic transmission and behavior in the MyosinVA mutant mouse Flailer.
Bustos, F. J.; Pandian, S.; Haensgen, H.; Zhao, J.-P.; Strouf, H.; Heidenreich, M.; Swiech, L.; Deverman, B.; Gradinaru, V.; Zhang, F.; Constantine-Paton, M.
10.1101/2023.04.28.538685 — neuroscience — Posted on 2023-04-28
318 Rit2 loss in dopaminergic neurons drives a progressive Parkinsonian phenotype
Kearney, P. J.; Zhang, Y.; Tan, Y.; Kahuno, E.; Conklin, T.; Fagan, R. R.; Yue, Z.; Melikian, H. E.; Shaffer, S. A.; Pavchinskiy, R. G.
10.1101/2023.04.26.538430 — neuroscience — Posted on 2023-04-28
320 Prospective role of PAK6 and 14-3-3 gamma as biomarkers for Parkinson's disease
Giusto, E.; Maistrello, L.; Iannotta, L.; Giusti, V.; Iovino, L.; Bandopadhyay, R.; Antonini, A.; Bubacco, L.; Barresi, R.; Plotegher, N.; Greggio, E.; Civiero, L.
10.1101/2023.04.28.538525 — neuroscience — Posted on 2023-04-28
323 Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis
Zhang, T.; Li, S.; Tan, A. Y.; Na, J.; Chen, Z.; Damle, P.; Chen, X.; Choi, S.; Mishra, B.; Wang, D.; Grossman, S. R.; Jiang, X.; Li, Y.; Chen, Y.-T.; Xiang, J. Z.; Du, N.
10.1101/2023.04.26.538373 — cancer biology — Posted on 2023-04-28
325 STAPLER: Efficient learning of TCR-peptide specificity prediction from full-length TCR-peptide data
Kwee, B. P. Y.; Messemaker, M.; Marcus, E.; Oliveira, G.; Scheper, W.; Wu, C.; Teuwen, J.; Schumacher, T.
10.1101/2023.04.25.538237 — bioinformatics — Posted on 2023-04-28
332 Lack of mTORC2 signaling in CD11c+ myeloid cells inhibits their migration and ameliorates experimental colitis
Ignacio, A.; Cipelli, M.; Takiishi, T.; Aguiar, C. F.; Terra, F. F.; Ghirotto, B.; Silva, E. M.; Castoldi, A.; Magalhaes, Y. T.; Antonio, T.; Hiyane, M. I.; Andrade-Oliveira, V.; Forti, F. L.; Camara, N. O. S.
10.1101/2023.04.26.537895 — immunology — Posted on 2023-04-28
333 Exploration of T-cell immune responses by expression of a dominant-negative SHP1 and SHP2
Taylor, J.; Bulek, A.; Gannon, I.; Robson, M.; Kokalaki, E.; Grothier, T.; McKenzie, C.; El-Kholy, M.; Stavrou, M.; Traynor-White, C.; Lim, W. C.; Panagiotou, P.; Srivastava, S.; Baldan, V.; Sillibourne, J.; Ferrari, M.; Pule, M.; Thomas, S.
10.1101/2023.04.26.538403 — immunology — Posted on 2023-04-28
334 Mitochondrial fitness influences neuronal excitability of dopaminergic neurons from patients with idiopathic form of Parkinson's disease
Chlebanowska, P.; Szlaga, A.; Tejchman-Skrzyszewska, A.; Kot, M.; Konieczny, P.; Skrzypek, K.; Muszynska, A.; Sobocinska, M.; Golebiowska, K.; Labaj, P.; Blasiak, A.; Majka, M.
10.1101/2023.04.28.538698 — neuroscience — Posted on 2023-04-28
336 A Brain Model of Disturbed Self-Appraisal in Social Anxiety Disorder
Jamieson, A. J.; Harrison, B. J.; Delahoy, R.; Schmaal, L.; Felmingham, K.; Phillips, L.; Davey, C.
10.1101/2023.04.26.537105 — neuroscience — Posted on 2023-04-28
337 Site effects depth denoising and signal enhancement using dual-projection based ICA model
Hao, Y.; Xu, H.; Xia, M.; Yan, C.; Zhang, Y.; Zhou, D.; Karkkainen, T.; Nickerson, L. D.; Li, H.; Cong, F.
10.1101/2023.04.26.538366 — neuroscience — Posted on 2023-04-28
339 Organization of orbitofrontal-auditory pathways in the Mongolian gerbil
Ying, R.; Hamlette, L.; Nikoobakht, L.; Balaji, R.; Miko, N.; Caras, M. L.
10.1101/2023.04.25.538296 — neuroscience — Posted on 2023-04-28
341 Highly Potent Peptide Therapeutics To Prevent Protein Aggregation In Huntington s Disease
Khan, A.; Yuca, E.; Ozcelik, C. E.; Begli, O.; Oguz, O.; Kasirga, S.; Seker, U. O. S.
10.1101/2023.04.27.538016 — neuroscience — Posted on 2023-04-28
343 Statistical learning in epilepsy: Behavioral, anatomical, and causal mechanisms in the human brain
Aljishi, A.; Sherman, B. E.; Huberdeau, D. M.; Obaid, S.; Sivaraju, A.; Turk-Browne, N. B.; Damisah, E. C.
10.1101/2023.04.25.538321 — neuroscience — Posted on 2023-04-28
348 Machine Learning Identifies Plasma Proteomic Signatures of Descending Thoracic Aortic Disease
Momenzadeh, A.; Kreimer, S.; Guo, D.; Ayres, M.; Berman, D.; Chyu, K.-Y.; Shah, P. K.; Milewicz, D.; Azizzadeh, A.; Meyer, J. G.; Parker, S.
10.1101/2023.04.26.538468 — systems biology — Posted on 2023-04-28
350 Mtfp1 ablation enhances mitochondrial respiration and protects against hepatic steatosis
Patitucci, C.; Hernandez Camacho, J. D.; Vimont, E.; Cokelaer, T.; Chaze, T.; Giai Giainetto, Q.; Matondo, M.; Gazi, A.; Nemazanyy, I.; Stroud, D. A.; Hock, D. H.; Donnarumma, E.; Wai, T.
10.1101/2023.04.26.538374 — physiology — Posted on 2023-04-28
351 Improving the solubility of pseudo-hydrophobic Alzheimer's Disease medicinal chemicals through co-crystal formulation
Tse, A.; Janilkarn-Urena, I.; Lin, J.; Chang, X.; Efthymiou, C.; Idrissova, A.; Zhang, M.; Williams, C. K.; Magaki, S. D.; Vinters, H. V.; Davies, D. L.; Gonen, T.; Gukasyan, H.; Seidler, P. M.
10.1101/2023.04.25.538327 — pharmacology and toxicology — Posted on 2023-04-28
357 Evaluation and optimization of sequence-based gene regulatory deep learning models
Rafi, A. M.; Penzar, D.; Nogina, D.; Lee, D.; Vaishnav, E. D.; Lee, D.; Kim, N.; Kim, S.; Meshcheryakov, G.; Lando, A.; Yadollahpour, P.; Zinkevich, A.; Kim, D.; Shin, Y.; Kwak, I.-Y.; Kim, B.-C.; Lee, J.; DREAM Challenge Consortium, R. P.; Kim, S.; Regev, A.; Albrecht, J.; Gong, W.; Kulakovskiy, I. V.; Meyer, P.; de Boer, C.
10.1101/2023.04.26.538471 — genomics — Posted on 2023-04-28
358 Improved gene annotation of the fungal wheat pathogen Zymoseptoria tritici based on combined Iso-Seq and RNA-Seq evidence
Lapalu, N.; Lamothe, L.; Petit, Y.; Genissel, A.; Delude, C.; Feurtey, A.; Abraham, L. N.; Smith, D.; King, R.; Renwick, A.; Appertet, M.; Sucher, J.; Steindorff, A. S.; Goodwin, S. B.; Grigoriev, I. V.; Hane, J.; Rudd, J.; Stukenbrock, E.; Croll, D.; Scalliet, G.; Lebrun, M.-H.
10.1101/2023.04.26.537486 — genomics — Posted on 2023-04-28
361 Chimeric Antigen Receptor Macrophages Target and Resorb Amyloid Plaques in a Mouse Model of Alzheimer's Disease
Pan, Q.; Yan, P.; Kim, A. B.; Xiao, Q.; Haecker, H.; Epelman, S.; Grajales-Reyes, G. E.; Diwan, A.; Lee, J.-M.; DeSelm, C. J.
10.1101/2023.04.28.538637 — immunology — Posted on 2023-04-28
362 Gut microbiota and metabolites drive chronic sickle cell disease pain
Sadler, K. E.; Atkinson, S. N.; Ehlers, V. L.; Waltz, T. B.; Hayward, M.; Rodriguez Garcia, D. M.; Salzman, N. H.; Stucky, C. L.; Brandow, A. M.
10.1101/2023.04.25.538342 — neuroscience — Posted on 2023-04-28
364 Targeting Transferrin Receptor to Transport Antisense Oligonucleotides Across the Blood-Brain Barrier
Barker, S. J.; Thayer, M. B.; Kim, C.; Tatarakis, D.; Simon, M.; Dial, R. L.; Nilewski, L.; Wells, R. C.; Zhou, Y.; Afetian, M.; Chappell, A.; Chew, K. S.; Chow, J.; Clemens, A.; Discenza, C. B.; Dugas, J. C.; Dwyer, C.; Earr, T.; Ha, C.; Huynh, D.; Jayaraman, S.; Kwan, W.; Mahon, C.; Pizzo, M.; Roche, E.; Sanders, L.; Stergioulis, A.; Tong, R.; Tran, H.; Zuchero, J.; Estrada, A. A.; Gadkar, K.; Koth, C. M.; Sanchez, P. E.; Thorne, R. G.; Watts, R. J.; Sandmann, T.; Kane, L. A.; Rigo, F.; Dennis, M. S.; Lewcock, J. W.; DeVos, S. L.
10.1101/2023.04.25.538145 — neuroscience — Posted on 2023-04-28
365 Lightning Pose: improved animal pose estimation via semi-supervised learning, Bayesian ensembling, and cloud-native open-source tools
Biderman, D.; Whiteway, M. R.; Hurwitz, C.; Greenspan, N. R.; Lee, R. S.; Vishnubhotla, A.; Schartner, M.; Huntenburg, J. M.; Khanal, A.; Meijer, G. T.; Noel, J.-P.; Pan-Vazquez, A.; Socha, K. Z.; Urai, A. E.; The International Brain Laboratory, ; Warren, R.; Noone, D.; Pedraja, F.; Cunningham, J.; Sawtell, N. B.; Paninski, L.
10.1101/2023.04.28.538703 — neuroscience — Posted on 2023-04-28
368 African rice (Oryza glaberrima) genomic introgressions impacting upon panicle architecture in Asian rice (O. sativa) lead to the identification of key QTLs
Adam, h.; Gutierrez, A.; Coudert, M.; Sabot, F.; Ntakirutimana, F.; Serret, J.; Orjuela, J.; Tregear, J.; Jouannic, S.; Lorieux, M.
10.1101/2023.04.25.538245 — plant biology — Posted on 2023-04-28
370 Synovial macrophage activation mediates pain experiences in experimental knee osteoarthritis
Blackler, G.; Lai-Zhao, Y.; Klapak, J.; Philpott, H. T.; Pitchers, K. K.; Maher, A. R.; Fiset, B.; Walsh, L. A.; Gillies, E. R.; Appleton, C. T.
10.1101/2023.04.25.538261 — physiology — Posted on 2023-04-28
371 Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 that Exhibits Antiviral Efficacy in SARS-CoV-2 Infected African Green Monkeys
Mackman, R. L.; Kalla, R.; Babusis, D.; Pitts, J.; Barrett, K. T.; Chun, K.; Du Pont, V.; Rodriguez, L.; Moshiri, J.; Xu, Y.; Lee, M.; Lee, G.; Bleier, B.; Nguyen, A.-Q.; O'Keefe, B. M.; Ambrosi, A.; Cook, M.; Yu, J.; Dempah, K. E.; Bunyan, E.; Riola, N. C.; Lu, X.; Liu, R.; Davie, A.; Hsiang, T.-Y.; Gale, M.; Niedziela-Majka, A.; Feng, J. Y.; Hedskog, C.; Bilello, J. P.; Subramanian, R.; Cihlar, T.
10.1101/2023.04.28.538473 — pharmacology and toxicology — Posted on 2023-04-28
372 The potential of Senicapoc, a KCNN4 inhibitor, for the prevention and treatment of breast cancer
Chenevix-Trench, G.; Britt, K.; Xiao, C.; Miranda, M.; Shi, W.; Beesley, J.; Saunus, J.; Civitarese, A.; Black, D.; Ruppert, M.; Perreira, M.; Jackson, S.; Teale, Z.; Carter-Cusack, D.; Kalinowski, L.; McCart Reed, A.; Handoko, H.; Chen, X.; Bessette, D.; MacDonald, K.; Lakhani, S.; Al-Ejeh, F.
10.1101/2023.04.25.538345 — cancer biology — Posted on 2023-04-28
375 Learning the Language of Antibody Hypervariability
Singh, R.; Im, C.; Sorenson, T.; Qiu, Y.; Wendt, M.; Nanfack, Y.; Bryson, B. D.; Berger, B.
10.1101/2023.04.26.538476 — bioinformatics — Posted on 2023-04-28
376 Clade-Specific MPXV PCR Assays
Negron, D. A.; Tolli, N.; Guertin, S.; Wollen-Roberts, S.; Mitchell, S.; Haas, J.; Pratt, C.; Jennings, K.; Abramson, B.; Brinkac, L.; Ashford, D.
10.1101/2023.04.24.538151 — bioinformatics — Posted on 2023-04-28
381 Amphiphilic particle-stabilized nanoliter droplet reactors with a multi-modal portable reader for distributive biomarker quantification
Shah, V.; Yang, X.; Arnheim, A.; Udani, S.; Tseng, D.; Luo, Y.; Ouyang, M.; Destgeer, G.; Garner, O.; Koydemir, H. C.; Ozcan, A.; Di Carlo, D.
10.1101/2023.04.24.538181 — bioengineering — Posted on 2023-04-28
382 Computational Mechanobiology Model Evaluating Healing of Postoperative Cavities Following Breast-Conserving Surgery
Harbin, Z. J.; Sohutskay, D. O.; Vanderlaan, E.; Fontaine, M. A.; Mendenhall, C.; Fisher, C. S.; Voytik-Harbin, S. L.; Buganza Tepole, A.
10.1101/2023.04.26.538467 — bioengineering — Posted on 2023-04-28
384 Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape
Ratnasinghe, B. D.; Haque, N.; Wagenknecht, J. B.; Jensen, D. R.; Esparza, G. V.; Leverence, E. N.; Milech de Assuncao, T.; Mathison, A. J.; Lomberk, G. A.; Smith, B. C.; Volkman, B. F.; Urrutia, R.; Zimmermann, M. T.
10.1101/2023.04.28.536249 — genomics — Posted on 2023-04-28
385 Phylogenomic Analyses Reveal Widespread Gene Flow During the Early Radiation of Oaks and Relatives (Fagaceae: Quercoideae)
Liu, S.; Yang, Y.; Tian, Q.; Yang, Z.; Li, S.; Valdes, P. J.; Farnsworth, A.; Kates, H. R.; Siniscalchi, C. M.; Guralnick, R. P.; Soltis, D. E.; Soltis, P. S.; Stull, G. W.; Folk, R. A.; Yi, T.
10.1101/2023.04.25.538215 — evolutionary biology — Posted on 2023-04-28
386 Not one, but multiple radiations underlie the biodiversity of Madagascar's endangered lemurs
Everson, K. M.; Pozzi, L.; Barrett, M. A.; Blair, M. E.; Donohue, M. E.; Kappeler, P. M.; Kitchener, A. C.; Lemmon, A. R.; Lemmon, E. M.; Pavon-Vazquez, C. J.; Radespiel, U.; Randrianambinina, B.; Rasoloarison, R. M.; Rasoloharijaona, S.; Roos, C.; Salmona, J.; Yoder, A. D.; Zenil-Ferguson, R.; Zinner, D.; Weisrock, D. W.
10.1101/2023.04.26.537867 — evolutionary biology — Posted on 2023-04-28
387 The duplication of genomes and gene regulatory networks and its potential for evolutionary adaptation and survival
Ebadi, M.; Bafort, Q.; Mizrachi, E.; Audenaert, P.; Simoens, P.; Van Montagu, M.; Bonte, D.; Van de Peer, Y.
10.1101/2023.04.28.538696 — evolutionary biology — Posted on 2023-04-28
389 Gut microbiota and maternal immune transfer at birth influence pre-allergic clinical outcome.
Villette, R.; Traore, D.; Dhilly, E.; Foucault, P.; Parisel, E.; Sauce, D.; Gorochov, G.; Kayem, G.; Schuhmacher, M.; Annesi-Maesano, I.; Larsen, M.; EarlyFOOD study group,
10.1101/2023.04.25.537372 — immunology — Posted on 2023-04-28
390 Group 2 innate lymphoid cells constrain type 3/17 lymphocytes in shared stromal niches to restrict liver fibrosis
Sbierski-Kind, J.; Cautivo, K. M.; Wagner, J.; Dahlgren, M. W.; Nilsson, J.; Krasilnikov, M.; Mroz, N. M.; Lizama, C. O.; Gan, A. L.; Matatia, P. R.; Taruselli, M. T.; Chang, A. A.; Caryotakis, S.; O'Leary, C.; Kotas, M.; Mattis, A. N.; Peng, T.; Locksley, R. M.; Molofsky, A. B.
10.1101/2023.04.26.537913 — immunology — Posted on 2023-04-28
391 A SREBF2-dependent gene program drives an immunotolerant dendritic cell population during cancer progression
Plebanek, M. P.; Xue, Y.; Nguyen, Y.-V.; DeVito, N.; Wang, X.; Holtzhausen, A.; Beasley, G.; Yarla, N.; Theivanthiran, B.; Hanks, B. A.
10.1101/2023.04.26.538456 — immunology — Posted on 2023-04-28
392 WNK1 enforces macrophage lineage fidelity
Trzeciak, A. J.; Rojas, W. S.; Liu, Z.-L.; Krebs, A. S.; Wang, Z.; Saavedra, P. H. V.; Miranda, I. C.; Lipshutz, A.; Xie, J.; Huang, C.-L.; Overholtzer, M.; Glickman, M. S.; Parkhurst, C. N.; Vierbuchen, T.; Lucas, C. D.; Perry, J. S. A.
10.1101/2023.04.26.538482 — immunology — Posted on 2023-04-28
393 A Common Cause for Nystagmus in Different Congenital Stationary Night Blindness Mouse Models
Holzel, M.-B.; Winkelman, B. H. J.; Howlett, M. H. C.; Kamermans, W.; De Zeeuw, C. I.; Kamermans, M.
10.1101/2023.04.24.538135 — neuroscience — Posted on 2023-04-28
394 Leakage beyond the primary infarction: A temporal analysis of cerebrovascular dysregulation at sites of hippocampal secondary neurodegeneration following cortical photothrombotic stroke
Hood, R. J.; Sanchez Bezanilla, S.; Beard, D. J.; Rust, R.; Turner, R. J.; Stuckey, S. M.; Collins-Praino, L. E.; Walker, F. R.; Nilsson, M.; Ong, L. K.
10.1101/2023.04.24.538047 — neuroscience — Posted on 2023-04-28
397 Dorsal peduncular cortex activity modulates affective behaviors in mice
Botterill, J. J.; Khlaifia, A.; Appings, R.; Premachandran, H.; Cruz-Sanchez, A.; Arruda-Carvalho, M.
10.1101/2023.04.25.538301 — neuroscience — Posted on 2023-04-28
398 Leveraging the power of 3D brain-wide imaging and mapping tools for brain injury research in murine models
Anwer, M.; LeDue, J.; Wang, Z.; Wang, S.; Cheng, W. H.; Burdyniuk, M.; Cheung, H.; Fan, J.; Barron, C.; Cripton, P. A.; Cembrowski, M. S.; Rossi, F.; Murphy, T. H.; Wellington, C.
10.1101/2023.04.27.537761 — neuroscience — Posted on 2023-04-28
400 Perfusion estimation using MRI-based measurements and a porous media flow model
Lorentzen, R. J.; Naevdal, G.; Saevareid, O.; Hodneland, E.; Hanson, E. A.; Munthe-Kaas, A.
10.1101/2023.04.25.538213 — systems biology — Posted on 2023-04-28
405 Imetelstat-Mediated Alterations in Fatty Acid Metabolism To Induce Ferroptosis As Therapeutic Strategy for Acute Myeloid Leukemia
Bruedigam, C.; Porter, A. H.; Song, A.; Vroeg in de Wei, G.; Stoll, T.; Straube, J.; Cooper, L.; Cheng, G.; Kahl, V. F. S.; Sobinoff, A. P.; Ling, V. Y.; Jebaraj, B. M. C.; Janardhanan, Y.; Haldar, R.; Bray, L. J.; Bullinger, L.; Heidel, F. H.; Kennedy, G. A.; Hill, M. M.; Pickett, H. A.; Abdel-Wahab, O.; Hartel, G.; Lane, S. W.
10.1101/2023.04.25.538357 — cancer biology — Posted on 2023-04-28
406 Raynals, an online tool for the analysis of dynamic light scattering
Burastero, O.; Draper-Barr, G.; Raynal, B.; Chevreuil, M.; England, P.; Garcia-Alai, M. M.
10.1101/2023.04.25.538274 — biophysics — Posted on 2023-04-28
411 EnGens: a computational framework for generation and analysis of representative protein conformational ensembles
Conev, A.; Rigo, M. M.; Devaurs, D.; Fonseca, A. F.; Kalavadwala, H.; de Freitas, M. V.; Clementi, C.; Zanatta, G.; Antunes, D. A.; Kavraki, L.
10.1101/2023.04.24.538094 — bioinformatics — Posted on 2023-04-28
414 Longitudinal Investigation of Aortic Dissection in Mice with Computational Fluid Dynamics
Baeumler, K.; Phillips, E. H.; Gutierrez, N. G.; Fleischmann, D.; Marsden, A. L.; Goergen, C. J.
10.1101/2023.04.24.538163 — bioengineering — Posted on 2023-04-28
415 Precision pharmacological reversal of genotype-specific diet-induced metabolic syndrome in mice informed by transcriptional regulation
Wulfridge, P.; Davidovich, A.; Salvador, A. C.; Manno, G. C.; Tryggvadottir, R.; Idrizi, A.; Huda, M. N.; Bennett, B. J.; Adams, L. G.; Hansen, K. D.; Threadgill, D. W.; Feinberg, A. P.
10.1101/2023.04.25.538156 — genetics — Posted on 2023-04-28
417 Identifying the multiple drivers of Cactus diversification
Thompson, J. B.; Hernandez-Hernandez, T.; Keeling, G.; Priest, N. K.
10.1101/2023.04.24.538150 — evolutionary biology — Posted on 2023-04-28
420 A novel resistance reversion mechanism in a vancomycin-variable Enterococcus faecium strain
McInnes, R. S.; Snaith, A. E.; Dunn, S. J.; Papangeli, M.; Hardy, K. J.; Hussain, A.; van Schaik, W.
10.1101/2023.04.28.538149 — microbiology — Posted on 2023-04-28
421 Interdependence of primary and secondary somatosensory cortices for plasticity and texture discrimination learning
Pandey, A.; Kang, S.; Pacchiarini, N.; Wyszynska, H.; Grewal, A.; Griffiths, A. M.; Healy-Millett, I. M.; Masseri, Z.; Hardingham, N. R.; O'Neill, J.; Honey, R. C.; Fox, K. D.
10.1101/2023.04.25.538217 — neuroscience — Posted on 2023-04-28
422 Electrophysiological signatures of anxiety in Parkinson's disease
Yassine, S.; Almarouk, S.; Gschwandtner, U.; Auffret, M.; Hassan, M.; Verin, M.; Fuhr, P.
10.1101/2023.04.25.538260 — neuroscience — Posted on 2023-04-28
426 Metabolic consequences of non-severe burn injury are associated with increased plasma markers of inflammation and cardiovascular disease risk.
Ryan, M. J.; Raby, E.; Masuda, R.; Lodge, S.; Nitschke, P.; Maker, G. L.; Wist, J.; Holmes, E.; Whiley, L.; Wood, F. M.; Nicholson, J. K.; Fear, M. W.; Gray, N.
10.1101/2023.04.24.537960 — systems biology — Posted on 2023-04-28
428 Receptor-like cytoplasmic kinases belonging to different subfamilies mediate immune responses downstream of the Cf-4 resistance protein in Nicotiana benthamiana
Huang, W. R. H.; Braam, C.; Kretschmer, C.; Liu, H.; Ferik, F.; van der Burgh, A. M.; Pluis, M.; Hagan, A. O.; Landeo Villanueva, S.; Wu, J.; van Loosbroek, A.; Wang, Y.; Seidl, M. F.; Stuttmann, J.; Joosten, M. H.
10.1101/2023.04.25.538242 — plant biology — Posted on 2023-04-28
430 Cell based dATP delivery as a therapy for chronic heart failure.
Mhatre, K. N.; Mathieu, J.; Martinson, A.; Flint, G.; Blakley, L. P.; Tabesh, A.; Reinecke, H.; Yang, X.; Guan, X.; Murali, E.; Klaiman, J. M.; Odom, G. L.; Brown, M. B.; Tian, R.; Hauschka, S. D.; Raftery, D.; Moussavi-Harami, F.; Regnier, M.; Murry, C. E.
10.1101/2023.04.24.538108 — pathology — Posted on 2023-04-28
432 Spatial transcriptomics reveal pitfalls and opportunities for the detection of rare high-plasticity breast cancer subtypes
Coutant, A.; Cockenpot, V.; Muller, L.; Degletagne, C.; Pommier, R.; Tonon, L.; Ardin, M.; Michallet, M.-C.; Caux, C.; Laurent, M.; Morel, A.-P.; Saintigny, P.; Puisieux, A.; Ouzounova, M.; Martinez, P.
10.1101/2023.04.24.538061 — cancer biology — Posted on 2023-04-28
433 Metabolic Reprogramming by Histone Deacetylase Inhibition Selectively Targets NRF2-activated tumors.
Karagiannis, D.; Wu, W.; Li, A.; Hayashi, M.; Chen, X.; Yip, M.; Mangipudi, V.; Xu, X.; Sanchez-Rivera, F. J.; Soto-Feliciano, Y. M.; Ye, J.; Papagiannakopoulos, T.; Lu, C.
10.1101/2023.04.24.538118 — cancer biology — Posted on 2023-04-28
434 The mitochondrial Ca2+ channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation
Fernandez Garcia, E.; Paudel, U.; Noji, M. C.; Bowman, C. E.; Pitarresi, J. R.; Rustgi, A. K.; Wellen, K. E.; Arany, Z.; Weissenrieder, J. S.; Foskett, J. K.
10.1101/2023.04.26.538295 — cancer biology — Posted on 2023-04-28
435 Assessment of Total Oocyte Transcripts Representation through Single Ooplasm Biopsy in Bovine with High Reliability
Ambrizi, D. R.; Nociti, R. P.; De Bem, T. H. C.; Paixao, J. V. P.; Therrien, J.; De Matos, E. C.; Ferraz, J. B. S.; Chiaratti, M. R.; Sangalli, J.; Da Silveira, J. C.; Perecin, F.; Smith, L. C.; Meirelles, F. V.
10.1101/2023.04.24.538116 — bioinformatics — Posted on 2023-04-28
445 Rapid Synthesis of Cryo-ET Data for Training Deep Learning Models
Purnell, C.; Heebner, J.; Swulius, M. T.; Hylton, R.; Kabonick, S.; Grillo, M.; Grigoryev, S.; Heberle, F. A.; Waxham, N.; Swulius, M. T.
10.1101/2023.04.28.538636 — cell biology — Posted on 2023-04-28
446 Spatially-resolved profiling of the T-cell receptor repertoire in archival clinical specimens using FUME-TCRseq
Baker, A.-M.; Nageswaran, G.; Nenclares, P.; Ronel, T.; Smith, K.; Kimberley, C.; Lacle, M. M.; Bhide, S.; Harrington, K. J.; Melcher, A.; Rodriguez-Justo, M.; Chain, B.; Graham, T. A.
10.1101/2023.04.24.538037 — immunology — Posted on 2023-04-28
447 Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold
Qi, C.; Verheijen, B. M.; Kokubo, Y.; Shi, Y.; Tetter, S.; Murzin, A. G.; Nakahara, A.; Morimoto, S.; Vermulst, M.; Sasaki, R.; Aronica, E.; Hirokawa, Y.; Oyanagi, K.; Kakita, A.; Ryskeldi-Falcon, B.; Yoshida, M.; Hasegawa, M.; Scheres, S. H. W.; Goedert, M.
10.1101/2023.04.26.538417 — neuroscience — Posted on 2023-04-28
450 Immunogenicity and safety in pigs of PHH-1V, a SARS-CoV-2 RBD fusion heterodimer vaccine candidate
Moros, A.; Prefaneta, A.; Barreiro, A.; Perozo, E.; Fernandez, A.; Canete, M.; Gonzalez, L.; Garriga, C.; Pradenas, E.; Marfil, S.; Blanco, J.; Cebollada-Rica, P.; Sistere-Oro, M.; Meyerhans, A.; Prat Cabanas, T.; March, R.; Ferrer, L.
10.1101/2023.01.19.524684 — immunology — Posted on 2023-04-28
451 Concurrent infection of human brain with multiple species of Lyme disease spirochetes
Golovchenko, M.; Opelka, J.; Vancova, M.; Sehadova, H.; Kralikopva, V.; Dobias, M.; Raska, M.; Krupka, M.; Sloupenska, K.; Rudenko, N.
10.1101/2023.04.27.538619 — microbiology — Posted on 2023-04-28
453 Chimeric protein EWS-FLI1 drives cell proliferation in Ewing Sarcoma via overexpression of KCNN1.
Dupuy, M.; Gueguinou, M.; Postec, A.; Brion, R.; Tesfaye, R.; Mullard, M.; Regnier, L.; Amiaud, J.; Potier-Cartereau, M.; Chantome, A.; Brounais-Le Royer, B.; Baud'huin, M.; Georges, S.; Lamoureux, F.; Ory, B.; Delattre, O.; Redini, F.; Vandier, C.; Verrecchia, F.
10.1101/2023.04.24.538050 — cancer biology — Posted on 2023-04-28
454 Selective effects of estradiol on human corneal endothelial cells
Han, S.; Mueller, C.; Wuebbolt, C.; Kilcullen, S.; Nayyar, V.; Calle Gonzalez, B.; Mahdavi Fard, A.; Floss, J.; Morales, M. J.; Patel, S. P.
10.1101/2023.04.27.538629 — cell biology — Posted on 2023-04-28
456 The Alzheimer's disease risk gene BIN1 modulates neural network activity via the regulation of L-type calcium channel expression in human-induced neurons
Saha, O.; Melo de Farias, A. R.; Pelletier, A.; Siedlecki-Wullich, D.; Gadaut, J.; Landeira, B. M. S.; Carrier, A.; Vreulx, A.-C.; Guyot, K.; Bonnefond, A.; Amouyel, P.; Queiroz, C. M.; Kilinc, D.; Delahaye, F.; Lambert, J.-C.; Costa, M. R.
10.1101/2022.01.18.476601 — neuroscience — Posted on 2023-04-28
462 ENGRAILED-1 transcription factor exerts a paracrine neurotrophic activity on adult spinal cord α-motoneurons.
Leboeuf, M.; Vargas-Abonce, S. E.; Peze-Hedsieck, E.; Dupont, E.; Jimenez-Alonso, L.; Moya, K. L.; Prochiantz, A.
10.1101/2022.08.16.504081 — neuroscience — Posted on 2023-04-28
463 LSM14B is essential for mitochondrial clustering in the oocyte meiosis
Wan, Y.; Yang, S.; Li, T.; Cai, Y.; Zhang, M.; Huang, T.; Lv, Y.; Lu, G.; Li, J.; Sha, Q.; Chen, Z.-J.; Liu, H.
10.1101/2023.04.24.538190 — developmental biology — Posted on 2023-04-28
465 p53 promotes revival stem cells in the regenerating intestine after severe radiation injury
Morral, C.; Ayyaz, A.; Kuo, H.-C.; Fink, M.; Verginadis, I.; Daniel, A. R.; Burner, D. N.; Driver, L. M.; Satow, S.; Hasapis, S.; Ghinnagow, R.; Luo, L.; Ma, Y.; Attardi, L. D.; Koumenis, C.; Minn, A. J.; Wrana, J. L.; Lee, C.-L.; Kirsch, D. G.
10.1101/2023.04.27.538576 — cell biology — Posted on 2023-04-28
466 Flexing fish: cell surface plasticity in response to shape change in the whole organism
Hall, T. E.; Ariotti, N.; Lo, H. P.; Ferguson, C. E.; Martel, N.; Lim, Y.-W.; Giacomotto, J.; Parton, R. G.
10.1101/2023.04.28.538646 — cell biology — Posted on 2023-04-28
467 Fission yeast CK1 promotes DNA double-strand break repair through both homologous recombination and non-homologous end joining
Cullati, S. N.; Zhang, E.; Shan, Y.; Guillen, R. X.; Chen, J.-S.; Navarrete-Perea, J.; Elmore, Z. C.; Ren, L.; Gygi, S. P.; Gould, K. L.
10.1101/2023.04.27.538600 — cell biology — Posted on 2023-04-28
468 Receptor endocytosis orchestrates the spatiotemporal bias of β-arrestin signaling
Toth, A. D.; Szalai, B.; Kovacs, O. T.; Garger, D.; Prokop, S.; Balla, A.; Inoue, A.; Varnai, P.; Turu, G.; Hunyady, L.
10.1101/2023.04.27.538587 — cell biology — Posted on 2023-04-28
473 Modulatory dynamics of periodic and aperiodic activity in respiration-brain coupling
Kluger, D. S.; Forster, C.; Abbasi, O.; Chalas, N.; Villringer, A.; Gross, J.
10.1101/2022.07.14.500026 — neuroscience — Posted on 2023-04-28
475 Molecular basis and validation of the interactions of neuronal Mintproteins with Munc18-1 and their cellular interactome predicted byAlphaFold2
Weeratunga, S.; Gormal, R.; Liu, M.; Eldershaw, D.; Livingstone, E.; Malapaka, A.; Wallis, T.; Bademosi, A.; Jiang, A.; Healy, M.; Meunier, F.; Collins, B.
10.1101/2023.02.20.529329 — biochemistry — Posted on 2023-04-28
476 Abundant capped RNAs are derived from mRNA cleavage at 3'UTR G-Quadruplexes
Haberman, N.; Digby, H.; Faraway, R.; Cheung, R.; Jobbins, A. M.; Parr, C.; Yasuzawa, K.; Kasukawa, T.; Yip, C. W.; Kato, M.; Takahashi, H.; Carninci, P.; Vernia, S.; Ule, J.; Sibley, C. R.; Martinez-sanchez, A.; Lenhard, B.
10.1101/2023.04.27.538568 — molecular biology — Posted on 2023-04-28
481 Evaluating possible maternal effect lethality of Naa10 knockout mice, and modulation of phenotypes for embryonic and neonatal lethality by genetic background and environment
Lyon, G.; Longo, J.; Garcia, A.; Inusa, F.; Marchi, E.; Shi, D.; Doerfel, M.; Arnesen, T.; Aldabe, R.; Lyons, S. K.; Nashat, M.; Bolton, D.
10.1101/2023.04.27.538618 — genetics — Posted on 2023-04-27
482 RhoA GEF Mcf2lb regulates rosette integrity during collective cell migration
Olson, H. M.; Maxfield, A.; Calistri, N. L.; Heiser, L. M.; Nechiporuk, A. V.
10.1101/2023.04.19.537573 — developmental biology — Posted on 2023-04-27
483 Abundant capped RNAs are derived from mRNA cleavage at 3'UTR G-Quadruplexes
Haberman, N.; Digby, H.; Faraway, R.; Cheung, R.; Jobbins, A. M.; Parr, C.; Yasuzawa, K.; Kasukawa, T.; Yip, C. W.; Kato, M.; Takahashi, H.; Carninci, P.; Ule, J.; Sibley, C. R.; Martinez-sanchez, A.; Lenhard, B.; Vernia, S.
10.1101/2023.04.27.538568 — molecular biology — Posted on 2023-04-27
485 Characterization of an Australian outbreak Japanese Encephalitis virus genotype 4 isolate in mice and human cortical brain organoids
Nguyen, W.; Tang, B.; Stewart, R.; Yan, K.; Larcher, T.; Bishop, C. R.; Gyawali, N.; Devine, G.; Suhrbier, A.; Rawle, D. J.
10.1101/2023.04.26.538504 — microbiology — Posted on 2023-04-27
488 Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift
Song, G.; Yuan, M.; Liu, H.; Capozzola, T.; Lin, R. N.; Torres, J. L.; He, W.-t.; Musharrafieh, R.; Dueker, K.; Zhou, P.; Callaghan, S.; Mishra, N.; Yong, P.; Anzanello, F.; Avillion, G.; Vo, A. L.; Li, X.; Makhdoomi, M.; Feng, Z.; Zhu, X.; Peng, L.; Nemazee, D.; Safonova, Y.; Briney, B.; Ward, A. B.; Burton, D. R.; Wilson, I. A.; Andrabi, R.
10.1101/2023.04.26.538488 — immunology — Posted on 2023-04-27
489 Extracellular release of damaged mitochondria induced by cytotoxic conditioning exacerbates GVHD
Vijayan, V.; Yan, H.; Lohmeyer, J. K.; Prentiss, K. A.; Patil, R. V.; Barbarito, G.; Lopez, I.; Elezaby, A.; Peterson, K.; Baker, J.; Ostberg, N. P.; Bertaina, A.; Negrin, R. S.; Mochly-Rosen, D.; Weinberg, K.; Haileselassie, B.
10.1101/2023.04.24.538141 — immunology — Posted on 2023-04-27
490 Enhancing CAR T cell therapy using Fab-Based Constitutively Heterodimeric Cytokine Receptors
Righi, M.; Gannon, I.; Robson, M.; Srivastava, S.; Kokalaki, E.; Grothier, T.; Nannini, F.; Allen, C.; Yuchen, B.; Sillibourne, J.; Cordoba, S. P.; Thomas, S.; Pule, M.
10.1101/2023.04.24.538039 — immunology — Posted on 2023-04-27
492 Sizes, Conformational fluctuations, and SAXS profiles for Intrinsically Disordered Proteins
Mugnai, M. L.; Chakraborty, D.; Kumar, A.; Nguyen, H. T.; Zeno, W.; Stachowiak, J. C.; Straub, J. E.; Thirumalai, D.
10.1101/2023.04.24.538147 — biophysics — Posted on 2023-04-27
493 On the dynamic contact angle of capillary-driven microflows in open channels
Tokihiro, J. C.; Berthier, J.; McManamen, A. M.; Phan, D. N.; Thongpang, S.; Theberge, A. B.
10.1101/2023.04.24.537941 — bioengineering — Posted on 2023-04-27
494 Designer DNA NanoGripper
Zhou, L.; Xiong, Y.; Cooper, L.; Shepherd, S.; Song, T.; Dwivedy, A.; Rong, L.; Wang, T.; Cunningham, B.; Wang, X.
10.1101/2023.04.26.538490 — bioengineering — Posted on 2023-04-27
496 Identification of allele-specific KIV-2 repeats and impact on Lp(a) measurements for cardiovascular disease risk
Behera, S.; Belyeu, J.; Chen, X.; Paulin, L. F.; Nguyen, N. Q.; Newman, E.; Mahmoud, M.; Menon, V. K.; Qi, Q.; Joshi, P.; Marcovina, S.; Rossi, M.; Roller, E.; Han, J.; Onuchic, V.; Avery, C. L.; Ballantyne, C. M.; Rodriguez, C. J.; Kaplan, R. C.; Muzny, D. M.; Metcalf, G. A.; Gibbs, R.; Yu, B.; Boerwinkle, E.; Eberle, M. A.; Sedlazeck, F. J.
10.1101/2023.04.24.538128 — genomics — Posted on 2023-04-27
497 Epigenetic control of myogenic identity of human muscle stem cells in Duchenne Muscular Dystrophy
Massenet, J.; Weiss-Gayet, M.; Bandukwala, H.; Magnan, M.; Hubas, A.; Nusbaum, P.; Desguerre, I.; Gitiaux, C.; Dilworth, F. J.; Chazaud, B.
10.1101/2023.04.26.538414 — genomics — Posted on 2023-04-27
504 Migratory pattern of zoonotic Toxocara cati and T. canis in experimentally infected pigs
Poulsen, C. S.; Yoshida, A.; Wellbrant, T. T.; Leifsson, P. S.; Skallerup, P.; Thamsborg, S. M.; Nejsum, P.
10.1101/2023.04.27.538522 — microbiology — Posted on 2023-04-27
505 HlyF, an underestimated virulence factor of uropathogenic Escherichia coli
Chagneau, C. V.; Payros, D.; Goman, A.; Goursat, C.; David, L.; Okuno, M.; Bordignon, P.-J.; Seguy, C.; Massip, C.; Branchu, P.; Ogura, Y.; Nougayrede, J.-P.; Marenda, M.; Oswald, E.
10.1101/2023.04.27.538512 — microbiology — Posted on 2023-04-27
507 Butyrate enhances Clostridioides difficile sporulation in vitro
Baldassare, M. A.; Bhattacharjee, D.; Coles, J. D.; Nelson, S.; McCollum, C. A.; Seekatz, A. M.
10.1101/2023.04.27.538596 — microbiology — Posted on 2023-04-27
509 Understanding the Mechanisms of Salmonella Typhimurium resistance to Cannabidiol
Ibrahim, I.; Ayariga, J. A.; Xu, J.; Abugri, D. A.; Robertson, B.; Ajayi, O. S.
10.1101/2023.04.27.538601 — microbiology — Posted on 2023-04-27
510 Ancient methicillin-resistant Staphylococcus aureus: expanding current knowledge using molecular epidemiological characterization of a Swiss legacy collection
Benvenga, V.; Cuenod, A.; Purushothaman, S.; Dasen, G.; Weisser, M.; Bassetti, S.; Roloff, T.; Siegemund, M.; Heininger, U.; Bielicki, J. A.; Wehrli, M.; Friderich, P.; Frei, R.; Widmer, A.; Herzog, K.; Fankhauser, H.; Nolte, O.; Bodmer, T.; Risch, M.; Dubuis, O.; Pranghofer, S.; Calligaris-Maibach, R.; Graf, S.; Tschudin-Sutter, S.; Perreten, V.; Seth-Smith, H. M. B.; Egli, A.
10.1101/2023.04.27.538514 — microbiology — Posted on 2023-04-27
511 Geographical Survey of the Mycobiome and Microbiome of Southern California Glassy-winged Sharpshooters
Ettinger, C. L.; Wu-Woods, J.; Kurbessoian, T. L.; Brown, D. J.; Pacheco, I. d. S.; Vindiola, B. G.; Walling, L. L.; Atkinson, P. W.; Byrne, F. J.; Redak, R.; Stajich, J. E.
10.1101/2023.04.27.538478 — microbiology — Posted on 2023-04-27
518 Label-free Identification of Protein Aggregates Using Deep Learning
Ibrahim, K. A.; Grussmayer, K. S.; Riguet, N.; Feletti, L.; Lashuel, H. A.; Radenovic, A.
10.1101/2023.04.21.537833 — bioengineering — Posted on 2023-04-27
520 Differential Regulation of Retinoic Acid Metabolism in Fanconi Anemia
Blaize, J.; Noori, B.; Hunter, K.; Henrikson, K.; Atoyan, J.; Ardito, A.; Donovan, F.; Chandrasekharappa, S.; Schindler, D.; Howlett, N. G.
10.1101/2023.04.06.535759 — biochemistry — Posted on 2023-04-27
521 Comprehensive locus-specific L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites.
Lanciano, S.; Philippe, C.; Sarkar, A.; Pratella, D.; Domrane, C.; Doucet, A. J.; van Essen, D.; Saccani, S.; Ferry, L.; Defossez, P.-A.; Cristofari, G.
10.1101/2023.01.03.522582 — genomics — Posted on 2023-04-27
528 Non-invasive stimulation of the human striatum disrupts reinforcement learning of motor skills
Vassiliadis, P.; Beanato, E.; Popa, T.; Windel, F.; Morishita, T.; Neufeld, E.; Duque, J.; Derosiere, G.; Wessel, M. J.; Hummel, F. C.
10.1101/2022.11.07.515477 — neuroscience — Posted on 2023-04-27
529 Moonlight synchronous flights across three western palearctic swifts mirror size dependent prey preferences
Hufkens, K.; Meier, C. M.; Evens, R.; Aran Paredes, J.; Karaardic, H.; Vercauteren, S.; Van Gysel, A.; Fox, J. W.; Pacheco, C. M.; da Silva, L. P.; Fernandes, S.; Henriques, P.; Elias, C.; Costa, L. T.; Poot, M.; Kearsley, L.
10.1101/2023.04.25.538243 — animal behavior and cognition — Posted on 2023-04-27
530 Dispersal in Kentish plovers (Charadrius alexandrinus): Adult females perform furthest movements
Cimiotti, D. V.; Eberhart-Phillips, L. J.; Audevard, A.; Joan Garcias Salas, P. J. G. S.; Gelinaud, G.; Günther, K.; Rocha, A.; Schulz, R.; van der Winden, J.; Schmaljohann, H.; Küpper, C.
10.1101/2023.04.27.538510 — animal behavior and cognition — Posted on 2023-04-27
533 HIV-1 infection of genetically engineered iPSC-derived central nervous system-engrafted microglia in a humanized mouse model
Akbarian, S.; Min, A. K.; Chen, B. K.; Swartz, T. H.; de Witte, L.; Marro, S.; Doanman, D.; Durens, M.; St. Vil, S.; Masih, Z.; Graziani, M.; Javidfar, B.; Missall, R.; Mordelt, A.
10.1101/2023.04.26.538461 — neuroscience — Posted on 2023-04-27
534 Spinal Cord Injury regulates circular RNA expression in axons
Siddiq, M. M.; Toro, C. A.; Johnson, N. P.; Hansen, J.; Xiong, Y.; Mellado, W.; Tolentino, R. E.; Johnson, K.; Jayaraman, G.; Suhail, Z.; Harlow, L.; Beaumont, K. G.; Sebra, R. G.; Willis, D. E.; Cardozo, C. P.; Iyengar, R.
10.1101/2023.04.26.538466 — neuroscience — Posted on 2023-04-27
535 Protective effects of polyphenol-rich extracts against neurotoxicity elicited by paraquat or rotenone in cellular models of Parkinson's disease
Tambe, M. A.; Jacquet, A. d. R.; Strathearn, K. E.; Yousef, G. G.; Grace, M. H.; Ferruzzi, M. G.; Wu, Q.; Simon, J. E.; Lila, M. A.; Rochet, J.-C.
10.1101/2023.04.26.538474 — neuroscience — Posted on 2023-04-27
540 Endothelial structure contributes to heterogeneity in brain capillary diameter
Sargent, S. M.; Bonney, S. K.; Li, Y.; Stamenkovic, S.; Takeno, M.; Coelho-Santos, V.; Shih, A. Y.
10.1101/2023.04.26.538503 — neuroscience — Posted on 2023-04-27
542 Psychedelic Concentrations of Nitrous Oxide Reduce Functional Differentiation in Frontoparietal and Somatomotor Cortical Networks
Dai, R.; Huang, Z.; Larkin, T. E.; Tarnal, V.; Picton, P.; Vlisides, P. E.; Janke, E.; McKinney, A.; Hudetz, A. G.; Harris, R. E.; Mashour, G. A.
10.1101/2023.04.26.538483 — neuroscience — Posted on 2023-04-27
547 Transcriptomic Analysis Of The Ocular Posterior Segment Completes A Cell Atlas Of The Human Eye
Monaverfeshani, A.; Yan, W.; Pappas, C.; Odenigbo, K. A.; He, Z.; van Zyl, T.; Segre, A.; Hageman, G.; Sanes, J. R.
10.1101/2023.04.26.538447 — cell biology — Posted on 2023-04-27
549 PALS1 is a key regulator of the lateral distribution of tight junction proteins in renal epithelial cells.
Groh, A.-C.; Kleimann, S.; Nedvestky, P.; Behrens, M.; Moeller-Kerutt, A.; Hoeffken, V.; Ghosh, S.; Hansen, U.; Krahn, M. P.; Ludwig, A.; Ebnet, K.; Pavenstaedt, H.; Weide, T.
10.1101/2023.04.27.538411 — cell biology — Posted on 2023-04-27
550 Live-cell super-resolution nanoscopy reveals modulation of cristae dynamics in bioenergetically compromised mitochondria
Golombek, M.; Tsigaras, T.; Schaumkessel, Y.; Haensch, S.; Weidtkamp-Peters, S.; Anand, R.; Reichert, A. S.; Kondadi, A. K.
10.1101/2023.04.27.538553 — cell biology — Posted on 2023-04-27
552 MYPT1 is a non-canonical AKAP that tethers PKA to the MLCP signaling node
Khalil, J. S.; Saldanha, P. A.; Blair, C. M.; Ling, J.; Ji, W.; Baillie, G. S.; Naseem, K. M.; Nikitenko, L. L.; Rivero, F.
10.1101/2023.04.27.538407 — cell biology — Posted on 2023-04-27
553 Quantifying cell viability through organelle ratiometric probing
Chen, R.; Qiu, K.; Han, G.; Kundu, B. K.; Ding, G.; Sun, Y.; Diao, J.
10.1101/2023.04.26.538448 — cell biology — Posted on 2023-04-27
555 Development of Constrained Peptide Inhibitors Targeting an Oncogenic E3 Ubiquitin Ligase
Zenkeviciute, G.; Xu, W.; Iegre, J.; Seki, H.; Tan, Y. S.; Rowling, P. J.; Ferrer, F.; Verma, C. S.; Spring, D.; Laman, H.; Itzhaki, L.
10.1101/2023.04.27.535981 — cancer biology — Posted on 2023-04-27
556 Ferroptosis-Protective Membrane Domains in Quiescence
Megarioti, A. H.; Athanasopoulos, A.; Koulouris, D.; Esch, B. M.; Makridakis, M.; Lygirou, V.; Samiotaki, M.; Zoidakis, J.; Sophianopoulou, V.; Andre, B.; Froehlich, F.; Gournas, C.
10.1101/2023.04.27.538084 — cell biology — Posted on 2023-04-27
557 Local Monomer Levels and Established Filaments Potentiate Non-Muscle Myosin 2 Assembly
Quintanilla, M. A.; Patel, H.; Wu, H.; Sochacki, K. A.; Akamatsu, M.; Rotty, J. D.; Korobova, F.; Bear, J. E.; Taraska, J. W.; Oakes, P. W.; Beach, J. R.
10.1101/2023.04.26.538303 — cell biology — Posted on 2023-04-27
558 TorsinA is essential for the timing and localization of neuronal nuclear pore complex biogenesis
Kim, S.; Phan, S.; Shaw, T. R.; Ellisman, M. H.; Veatch, S. L.; Barmada, S. J.; Pappas, S. S.; Dauer, W. T.
10.1101/2023.04.26.538491 — cell biology — Posted on 2023-04-27
560 The Novel Role of Midbody-Associated mRNAs in Regulating Abscission
Farmer, T.; Vaeth, K.; Han, K.-J.; Goering, R.; Taliaferro, M.; Prekeris, R.
10.1101/2022.10.27.514111 — cell biology — Posted on 2023-04-27
561 On stability of Canonical Correlation Analysis and Partial Least Squares with application to brain-behavior associations
Helmer, M.; Warrington, S. D.; Mohammadi-Nejad, A.-R.; Ji, J. L.; Howell, A.; Rosand, B.; Anticevic, A.; Sotiropoulos, S. N.; Murray, J. D.
10.1101/2020.08.25.265546 — neuroscience — Posted on 2023-04-27
562 The effect of pulse shape in theta-burst stimulation: monophasic vs biphasic TMS
Wendt, K.; Memarian Sorkhabi, M.; Stagg, C. J.; Fleming, M. K.; Denison, T.; O'Shea, J.
10.1101/2023.03.06.531158 — neuroscience — Posted on 2023-04-27
565 Chaotic aging: Intrinsically disordered proteins in aging-related processes
Manyilov, V. D.; Ilyinsky, N. S.; Nesterov, S. V.; Saqr, B. M. G. A.; Dayhoff, G. W.; Zinovev, E. V.; Matrenok, S. S.; Fonin, A. V.; Kuznetsova, I. M.; Turoverov, K. K.; Ivanovich, V.; Uversky, V. N.
10.1101/2023.04.22.537928 — bioinformatics — Posted on 2023-04-27
567 Towards universal synthetic heterotrophy using a metabolic coordinator
Sullivan, S. F.; Shetty, A.; Bharadwaj, T.; Krishna, N.; Trivedi, V. D.; Endalur Gopinarayanan, V.; Chappell, T. C.; Sellers, D. M.; Kumar R, P.; Nair, N. U.
10.1101/2022.11.02.514957 — synthetic biology — Posted on 2023-04-27
568 Integration of metabolism and regulation reveals rapid adaptability to growth on non-native substrates.
Trivedi, V. D.; Sullivan, S. F.; Choudhury, D.; Endalur Gopinarayanan, V.; Hart, T.; Nair, N. U.
10.1101/2022.05.21.492926 — synthetic biology — Posted on 2023-04-27
569 Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin
Teixeira-Nunes, M.; Retailleau, P.; Raoux-Barbot, D.; Comisso, M.; Missinou, A. A.; Velours, C.; Plancqueel, S.; Ladant, D.; Mechold, U.; Renault, L.
10.1101/2023.01.13.523968 — biochemistry — Posted on 2023-04-27
570 Elevated temperature alters microbial communities, but not decomposition rates, during three years of in-situ peat decomposition
Roth, S. W.; Griffiths, N. A.; Kolka, R. K.; Oleheiser, K. C.; Carrell, A. A.; Klingeman, D. M.; Seibert, A.; Chanton, J.; Hanson, P. J.; Schadt, C. W.
10.1101/2023.04.13.536719 — ecology — Posted on 2023-04-27
571 Glucocorticoids negatively relate to body mass on the short-term in a free-ranging ungulate
Lalande, L. D.; Gilot-Fromont, E.; Carbillet, J.; Debias, F.; Duhayer, J.; Gaillard, J.-M.; Lemaitre, J.-F.; Palme, R.; Pardonnet, S.; Pellerin, M.; Rey, B.; Vuarin, P.
10.1101/2022.09.15.508076 — ecology — Posted on 2023-04-27
572 Functional specialization of hippocampal somatostatin-expressing interneurons
Chamberland, S.; Grant, G.; Machold, R. P.; Nebet, E. R.; Tian, G.; Hanani, M.; Kullander, K.; Tsien, R. W.
10.1101/2023.04.27.538511 — neuroscience — Posted on 2023-04-27
574 Frontal mechanisms underlying primate calls recognition by humans
Ceravolo, L.; Debracque, C.; Pool, E.; Gruber, T.; Grandjean, D.
10.1101/2023.02.13.528425 — neuroscience — Posted on 2023-04-27
583 An AI-based segmentation and analysis pipeline for high-field MR monitoring of cerebral organoids
Deininger, L.; Jung-Klawitter, S.; Richter, P.; Fischer, M.; Karimian-Jazi, K.; Breckwoldt, M.; Bendszus, M.; Heiland, S.; Kleesiek, J.; Mikut, R.; Huebschmann, D.; Schwarz, D.
10.1101/2023.04.07.535822 — developmental biology — Posted on 2023-04-27
584 Longitudinal Survey of Astrovirus infection in different bat species in Zimbabwe: Evidence of high genetic Astrovirus diversity
Chidoti, V.; De Nys, H.; Abdi, M.; Mashura, G.; Pinarello, V.; Chiweshe, N.; Matope, G.; Guerrini, L.; Pfulenyi, D.; Cappelle, J.; Mwandiringana, E.; Misse, D.; Elizabeth, G.; Bourgarel, M.; Liegeois, F.
10.1101/2023.04.14.536987 — molecular biology — Posted on 2023-04-27
585 Genetic evidence of a functional linkage between the RNA-dependent RNA polymerase and the highly structured S fragment located at the 5' end of the genome of foot-and-mouth disease virus.
Ward, J. C.; Lasecka-Dykes, L.; Dobson, S. J.; Gold, S.; Kingston, N. J.; Herod, M. R.; King, D. P.; Tuthill, T. J.; Rowlands, D. J.; Stonehouse, N. J.
10.1101/2023.04.26.538422 — molecular biology — Posted on 2023-04-27
586 BOUNTI: Brain vOlumetry and aUtomated parcellatioN for 3D feTal MRI
Uus, A. U.; Kyriakopoulou, V.; Makropoulos, A.; Fukami-Gartner, A.; Cromb, D.; Davidson, A.; Cordero-Grande, L.; Price, A. N.; Grigorescu, I.; Williams, L. Z. J.; Robinson, E. C.; Lloyd, D.; Pushparajah, K.; Story, L.; Hutter, J.; Counsell, S. J.; Edwards, A. D.; Rutherford, M. A.; Hajnal, J. V.; Deprez, M.
10.1101/2023.04.18.537347 — neuroscience — Posted on 2023-04-27
591 GWAS identifies candidate regulators of in planta regeneration in Populus trichocarpa
Nagle, M. F.; Yuan, J.; Kaur, D.; Ma, C.; Peremyslova, E.; Jiang, Y.; Nino de Rivera, A.; Jawdy, S.; Chen, J.-G.; Feng, K.; Yates, T. B.; Tuskan, G. A.; Muchero, W.; Li, F.; Strauss, S. H.
10.1101/2022.06.08.495082 — plant biology — Posted on 2023-04-27
594 Evidence of the simultaneous replications of active viruses in specimens positive for multiple respiratory viruses
Kawase, M.; Suwa, R.; Sugimoto, S.; Kakizaki, M.; Kume, Y.; Chishiki, M.; Ono, T.; Okabe, H.; Norito, S.; Ujike, M.; Hosoya, M.; Hashimoto, K.; Shirato, K.
10.1101/2023.04.26.538472 — microbiology — Posted on 2023-04-26
595 CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions
Li, E.; Benitez, C.; Boggess, S. C.; Koontz, M.; Rose, I. V. L.; Draeger, N.; Teter, O. M.; Samelson, A. J.; Ullian, E. M.; Kampmann, M.
10.1101/2023.04.26.538498 — neuroscience — Posted on 2023-04-27
600 Genomic epidemiology and multilevel genome typing of Bordetella pertussis
Payne, M.; Xu, Z.; Hu, D.; Kaur, S.; Octavia, S.; Sintchenko, V.; Lan, R.
10.1101/2023.04.26.538362 — microbiology — Posted on 2023-04-26
601 Shortwave infrared (SWIR) fluorescence imaging of peripheral organs in awake and freely moving mice
Arus, B. A.; Cosco, E. D.; Yiu, J.; Balba, I.; Bischof, T. S.; Sletten, E. M.; Bruns, O. T.
10.1101/2023.04.26.538387 — bioengineering — Posted on 2023-04-26
604 Structure determination of a DNA crystal by MicroED
Haymaker, A.; Bardin, A. A.; Gonen, T.; Martynowycz, M. W.; Nannenga, B. L.
10.1101/2023.04.25.538338 — biochemistry — Posted on 2023-04-26
605 Ketone bodies in Right Ventricular Failure: A Unique Therapeutic Opportunity
Blake, M.; Puchalska, P.; Kazmirczak, F.; Thenappan, T.; Crawford, P.; Prins, K.
10.1101/2023.04.26.538410 — biochemistry — Posted on 2023-04-26
607 Genome structure and population genomics of the canine heartworm Dirofilaria immitis
Gandasegui, J.; Power, R. I.; Curry, E.; Lau, D. C.-W.; O'Neill, C. M.; Wolstenholme, A.; Prichard, R.; Slapeta, J.; Doyle, S.
10.1101/2023.04.25.538225 — genomics — Posted on 2023-04-26
610 Analysis of DNA transposition by DNA transposases in human cells
Bigot, Y.; Yamadam, M.; Mueller, H.; Morell, V.; Alves, S.; Lecomte, T.; Kentsis, A.
10.1101/2023.04.26.538406 — molecular biology — Posted on 2023-04-26
611 Evidence of the simultaneous replications of active viruses in specimens positive for multiple respiratory viruses
Kawase, M.; Suwa, R.; Sugimoto, S.; Kakizaki, M.; Kume, Y.; Chishiki, M.; Ono, T.; Okabe, H.; Norito, S.; Ujike, M.; Hosoya, M.; Hashimoto, K.; Shirato, K.
10.1101/2023.04.26.538472 — microbiology — Posted on 2023-04-26
613 A pyridyl-furan series developed from Open Global Health Library blocks red blood cell invasion and protein trafficking in Plasmodium falciparum through potential inhibition of the parasites PI4KIIIb enzyme.
Ling, D. B.; Nguyen, W.; Looker, O.; Razook, Z.; McCann, K.; Barry, A. E.; Scheurer, C.; Wittlin, S.; Bullen, H. E.; Crabb, B. S.; Sleebs, B. E.; Gilson, P. R.
10.1101/2023.04.25.538349 — microbiology — Posted on 2023-04-26
614 Exploring Microbial Diversity and Functional Potential along the Bay of Bengal Coastline in Bangladesh: Insights from Amplicon Sequencing and Shotgun Metagenomics
Akter, S.; Rahman, M. S.; Ali, H.; Minch, B.; Mehzabin, K.; Siddique, M. M.; Galib, S. M.; Yasmin, F.; Azmuda, N.; Adnan, N.; Hasan, N. A.; Rahman, S. R.; Moniruzzaman, M.; Ahmed, M. F.
10.1101/2023.04.26.538428 — microbiology — Posted on 2023-04-26
617 The conformational landscape of a serpin N-terminal subdomain facilitates folding and in-cell quality control
Kaur, U.; Kihn, K. C.; Ke, H.; Kuo, W.; Gierasch, L. M.; Hebert, D. N.; Wintrode, P. L.; Deredge, D.; Gershenson, A.
10.1101/2023.04.24.537978 — biophysics — Posted on 2023-04-26
618 Assessment of three-dimensional RNA structure prediction in CASP15
Das, R.; Kretsch, R. C.; Simpkin, A. J.; Mulvaney, T.; Pham, P.; Rangan, R.; Bu, F.; Keegan, R.; Topf, M.; Rigden, D.; Miao, Z.; Westhof, E.
10.1101/2023.04.25.538330 — biophysics — Posted on 2023-04-26
620 Lesion-specific suppression of YAP/TAZ by biomimetic nanodrug ameliorates atherosclerosis development
Huang, H.-C.; Wang, T.-Y.; Rousseau, J.; Mungaray, M.; Michaud, C.; Plaisier, C.; Chen, Z. B.; Wang, K.-C.
10.1101/2023.04.24.537992 — bioengineering — Posted on 2023-04-26
621 Structure-Property-Processing Correlations of Graphene Bioscaffolds for Proliferation and Differentiation of C2C12 Cells
Karriem, L.; Eixenberger, J.; Frahs, S.; Convertino, D.; Webb, T.; Pandhi, T.; McLaughlin, K.; Enrriques, A.; Davis, P.; Subbaraman, H.; Coletti, C.; Oxford, J.; Estrada, D.
10.1101/2023.04.25.538356 — bioengineering — Posted on 2023-04-26
623 An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor
Aguirre, T.; Hostachy, S.; Dornan, G. L.; Neuenschwander, M.; Seyffarth, C.; Haucke, V.; Schuetz, A.; von Kries, J. P.; Fiedler, D.
10.1101/2023.04.26.538378 — biochemistry — Posted on 2023-04-26
630 Evidence for microbially-mediated tradeoffs between growth and defense throughout coral evolution
Epstein, H. E.; Brown, T.; Akinrinade, A. O.; McMinds, R.; Pollock, F. J.; Sonett, D.; Smith, S.; Bourne, D. G.; Carpenter, C. S.; Knight, R.; Willis, B. L.; Medina, M.; Lamb, J. B.; Thurber, R. V.; Zaneveld, J. R.
10.1101/2023.04.26.538152 — microbiology — Posted on 2023-04-26
632 The nuclear import receptor Kapβ2 protein modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD
cicardi, M. e.; Kankate, V.; Sriramoji, S.; Krishnamurthy, K.; ShamamandriMarkandaiah, S.; Verdone-Morris, B.; Girdhar, A.; Nelson, A. T.; Rivas, L. B.; Boehringer, A.; Haeusler, A.; Pasinelli, P.; Guo, L.; Trotti, D.
10.1101/2022.09.30.510384 — neuroscience — Posted on 2023-04-26
639 D-SPIN constructs gene regulatory network models from multiplexed scRNA-seq data revealing organizing principles of cellular perturbation response
Jiang, J.; Chen, S.; Tsou, T.; McGinnis, C. S.; Khazaei, T.; Zhu, Q.; Park, J. H.; Strazhnik, I.-M.; Hanna, J.; Chow, E. D.; Sivak, D. A.; Gartner, Z. J.; Thomson, M.
10.1101/2023.04.19.537364 — bioinformatics — Posted on 2023-04-26
642 Direction-dependent neural control of finger dexterity in humans
Rajchert, O.; Ofir-Geva, S.; Melul, Y.; Khoury-Mireb, M.; Wonderman Bar-Sela, O.; Granot, O.; Caspi, T.; Frenkel-Toledo, S.; Soroker, N.; Mawase, F.
10.1101/2023.04.25.538234 — neuroscience — Posted on 2023-04-26
643 Sensory innervation of masseter, temporal and lateral pterygoid muscles in common marmosets
Hovhannisyan, A. H.; Lindquist, K.; Belugin, S.; Mecklenburg, J.; Ibrahim, T.; Tram, M.; Corey, T.; Salmon, A.; Ruparel, S.; Ruparel, S.; Akopian, A.
10.1101/2023.02.10.528062 — neuroscience — Posted on 2023-04-26
645 Tumor cell heterogeneity drives spatial organization of the intratumoral immune response in squamous cell skin carcinoma
Tanaka, M.; Lum, L.; Hu, K. H.; Ledezma-Soto, C.; Superville, D. A.; Ng, K. M.; Adams, Z.; Kersten, K. H.; Fong, L.; Krummel, M. F.; Reeves, M. Q.
10.1101/2023.04.25.538140 — cancer biology — Posted on 2023-04-26
646 VirtualFlow 2.0 - The Next Generation Drug Discovery Platform Enabling Adaptive Screens of 69 Billion Molecules
Gorgulla, C.; Nigam, A.; Koop, M.; Cinaroglu, S. S.; Secker, C.; Haddadnia, M.; Kumar, A.; Malets, Y.; Hasson, A.; Levin-Konigsberg, R.; Radchenko, D.; Kumar, A.; Gehev, M.; Tang, M.; Li, M.; Aquilanti, P.-Y.; Gabb, H.; Alhossary, A.; Wagner, G.; Aspuru-Guzik, A.; Moroz, Y. S.; Fackeldey, K.; Arthanari, H.
10.1101/2023.04.25.537981 — bioinformatics — Posted on 2023-04-26
647 Epigenetically-regulated RNA-binding proteins signify malaria hypnozoite dormancy
Toenhake, C. G.; Voorberg-van der Wel, A.; Wu, H.; Kanyal, A.; Nieuwenhuis, I. G.; van der Werff, N. M.; Hofman, S.; Zeeman, A.-M.; Kocken, C. H. M.; Bartfai, R.
10.1101/2023.04.25.537952 — systems biology — Posted on 2023-04-26
648 De Novo Design of κ-Opioid Receptor Antagonists Using a Generative Deep Learning Framework
Salas-Estrada, L.; Provasi, D.; Qiu, X.; Kaniskan, H. U.; Huang, X.-P.; DiBerto, J.; Marcelo Lamim Ribeiro, J.; Jin, J.; Roth, B. L.; Filizola, M.
10.1101/2023.04.25.537995 — bioinformatics — Posted on 2023-04-26
649 Annelid adult cell type diversity and their pluripotent cellular origins
Alvarez-Campos, P.; Garcia-Castro, H.; Emili, E.; Perez-Posada, A.; Salamanca-Diaz, D. A.; Mason, V.; Metzger, B.; Bely, A. E.; Kenny, N.; Özpolat, B. D.; Solana, J.
10.1101/2023.04.25.537979 — genomics — Posted on 2023-04-26
651 Surveillance of Vermont wildlife in 2021-2022 reveals no detected SARS-CoV-2 viral RNA
Despres, H. W.; Mills, M. G.; Schmidt, M. M.; Gov, J.; Perez, Y.; Jindrich, M.; Crawford, A. M. L.; Kohl, W. T.; Rosenblatt, E.; Kubinski, H. C.; Simmons, B. C.; Nippes, M. C.; Goldenberg, A. J.; Murtha, K. E.; Nicoloro, S.; Harris, M. J.; Feeley, A. C.; Gelinas, T. K.; Cronin, M. K.; Frederick, R. S.; Thomas, M.; Johnson, M. E.; Murphy, J.; Lenzini, E. B.; Carr, P. A.; Berger, D. H.; Mehta, S. P.; Floreani, C. J.; Koval, A. C.; Young, A. L.; Fish, J. H.; Wallace, J.; Chaney, E.; Ushay, G.; Waterman, M.; Ross, R. S.; Vostal, E. M.; Thisner, M. C.; Gonet, K. E.; Deane, O. C.; Kari, P. R.; Rocka
10.1101/2023.04.25.538264 — microbiology — Posted on 2023-04-26
652 Intranasal VLP-RBD vaccine adjuvanted with BECC470 confers immunity against Delta SARS-CoV-2 challenge in K18-hACE2-mice
Damron, F. H.; Lee, K. S.; Rader, N. A.; Miller-Stump, O. A.; Cooper, M.; Wong, T. Y.; Amin, M. S.; Barbier, M.; Bevere, J. R.; Ernst, R. K.
10.1101/2023.04.25.538294 — immunology — Posted on 2023-04-26
653 Distinct blood CD3+ CD14+ T Cell-Monocyte complexes harbor HIV and are dynamic, glucose-dependent, and increased in individuals with glucose intolerance
Wanjalla, C. N.; Simmons, J.; Oakes, J.; Zhang, X.; Nochowivz, C.; Priest, S.; Bailin, S. S.; Watten, C. M.; Mashayekhi, M.; Beasley, H. K.; Wang, J.; Meenderink, L. M.; Sheng, Q.; Stolze, J.; Gangula, R.; Chopra, A.; Gabriel, C. L.; Temu, T.; Pakala, S.; Wilfong, E. M.; Gianella, S.; Phillips, E. J.; Harrison, D. G.; Hinton, A.; Kalams, S. A.; Mallal, S. A.; Koethe, J. R.
10.1101/2023.04.24.538020 — immunology — Posted on 2023-04-26
655 Regulation of adaptive growth decisions via phosphorylation of the TRAPPII complex in Arabidopsis
Wiese, C.; Abele, M.; Al, B.; Altmann, M.; Steiner, A.; Kalbfuss, N.; Strohmayr, A.; Ravikumar, R.; Park, C. H.; Brunschweiger, B.; Meng, C.; Facher, E.; Ehrhardt, D. W.; Falter-Braun, P.; Wang, Z.; Ludwig, C.; Assaad, F. F.
10.1101/2023.04.24.537966 — plant biology — Posted on 2023-04-26
656 Legionella pneumophila macrophage infectivity potentiator protein appendage domains modulate protein dynamics and inhibitor binding
Wiedemann, C.; Whittaker, J. J.; Perez Carrillo, V. H.; Goretzki, B.; Dajka, M.; Tebbe, F.; Harder, J.-M.; Krajczy, P.; Joseph, B.; Hausch, F.; Guskov, A.; Hellmich, U. A.
10.1101/2023.04.24.538046 — biophysics — Posted on 2023-04-26
658 Spatio-temporal X-linked gene reactivation and site-specific retention of epigenetic silencing in the in vivo germline.
Roidor, C.; Syx, L.; Beyne, E.; Zielinski, D.; Teissandier, A.; Lee, C.; Walter, M.; Servant, N.; Chebli, K.; Bourc'his, D.; Surani, M. A.; Borensztein, M.
10.1101/2023.04.25.532252 — developmental biology — Posted on 2023-04-26
659 A farnesyl-dependent structural role for CENP-E in expansion of the fibrous corona
Wu, J.; Raas, M. W. D.; Alcaraz, P. S.; Vos, H. R.; Tromer, E. C.; Snel, B.; Kops, G. J.
10.1101/2023.04.26.538394 — cell biology — Posted on 2023-04-26
661 New molecular signatures defining the differential proteostasis response in ALS-resistant and -sensitive motor neurons
Fiore, A. Z.; Maity, S.; Iannitelli, D. E.; Disi, A.; Rendleman, J.; Choi, H.; Mazzoni, E. O.; Vogel, C.
10.1101/2022.04.10.487765 — systems biology — Posted on 2023-04-26
662 Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia
Malyukova, A.; Lahnalampi, M.; Falques-Costa, T.; Polonen, P.; Sipola, M.; Mehtonen, J.; Teppo, S.; Viiliainen, J.; Lohi, O.; Hagstrom-Andersson, A.; Heinaniemi, M.; Sangfelt, O.
10.1101/2023.03.27.534308 — cancer biology — Posted on 2023-04-26
663 How far are we from personalized gene expression prediction using sequence-to-expression deep neural networks?
Sasse, A.; Ng, B.; Spiro, A.; Tasaki, S.; Bennett, D.; Gaiteri, C.; De Jager, P. L.; Chikina, M.; Mostafavi, S.
10.1101/2023.03.16.532969 — bioinformatics — Posted on 2023-04-26
674 A familial natural short sleep mutation promotes healthy aging and extends lifespan in Drosophila
Pandey, P.; Wall, P. K.; Lopez, S. R.; Dubuisson, O. S.; Zunica, E. R. M.; Dantas, W. S.; Kirwan, J. P.; Axelrod, C. L.; Johnson, A. E.
10.1101/2023.04.25.538137 — cell biology — Posted on 2023-04-26
675 Tension sensing by FAK governs nuclear mechanotransduction, endothelial transcriptome and fate
Akhter, M. Z.; Yazbeck, P.; Tauseef, M.; Anwar, M.; Hossen, F.; Datta, S.; Vellingiri, V.; Joshi, J. C.; Srivastava, N.; Lenzini, S.; Zhou, G.; Lee, J.; Jain, M. K.; Shin, J.-W.; Mehta, D.
10.1101/2023.04.24.538195 — cell biology — Posted on 2023-04-26
678 Target-identification and mechanism-of-action studies of indole terpenoid mimics reveal that proper spindle microtubule assembly is essential for Cdh1-mediated proteolysis of CENP-A
Peng, Y.; Zhang, Y.; Fang, R.; Jiang, H.; Lan, G.; Liu, Y.; Nie, Z.; Zhang, S.-D.; Ma, Y.; Yang, P.; Wang, F.; Ge, H.-H.; Zhang, W.-D.; Luo, C.; Li, A.; He, W.
10.1101/2023.04.25.538200 — cell biology — Posted on 2023-04-26
679 Characterization of Pro-Fibrotic Signaling Pathways using Human Hepatic Organoids
Guan, Y.; Fang, Z.; Hu, A.; Roberts, S.; Johansson, P. K.; Heilshorn, S. C.; Enejder, A.; Peltz, G.
10.1101/2023.04.25.538102 — cell biology — Posted on 2023-04-26
683 Discovery of microRNA-derived RNAs and proteins in human cells
Wu, H.; Huang, X.; Zhong, W.; Li, W.; Liu, Z.; Zhao, M.; Xi, X.; Cao, B.; Pu, Y.; Kong, X.; Zhao, H.; Zhang, R.; Lai, K.; Lv, X.; Lv, Y.; Bao, J.; Wang, M.; Xiong, Y.; Dong, L.; Zhang, J.; Zhang, G.; Hu, Y.; Xu, J.; Chen, Y. E.; Chen, S.
10.1101/2023.04.24.538138 — cell biology — Posted on 2023-04-26
685 DISCOVER-EEG: an open, fully automated EEG pipeline for biomarker discovery in clinical neuroscience
Gil Avila, C.; Bott, F. S.; Tiemann, L.; Hohn, V. D.; May, E. S.; Nickel, M. M.; Zebhauser, P. T.; Gross, J.; Ploner, M.
10.1101/2023.01.20.524897 — neuroscience — Posted on 2023-04-26
687 Pathogenic Mutations in the C2A Domain of Dysferlin form Amyloid that Activates the Inflammasome.
Scott, I. L.; Dominguez, M. J.; Snow, A.; Harsini, F. M.; Williams, J.; Fuson, K. L.; Thapa, R.; Bhattacharjee, P.; Cornwall, G. A.; Keyel, P. A.; Sutton, R. B.
10.1101/2023.04.24.538129 — biophysics — Posted on 2023-04-26
691 mRNA Location and Translation Rate Determine Protein Targeting to Dual Destinations
Gasparski, A. N.; Moissoglu, K.; Pallikkuth, S.; Meydan, S.; Guydosh, N. R.; Mili, S.
10.1101/2023.04.24.538105 — cell biology — Posted on 2023-04-26
692 Competition between transcription and loop extrusion modulates promoter and enhancer dynamics
Platania, A.; Erb, C.; Barbieri, M.; Molcrette, B.; Grandgirard, E.; de Kort, M. A.; Meaburn, K.; Taylor, T.; Shchuka, V. M.; Kocanova, S.; Monteiro Oliveira, G.; Mitchell, J. A.; Soutoglou, E.; Lenstra, T. L.; Molina, N.; Papantonis, A.; Bystricky, K.; Sexton, T.
10.1101/2023.04.25.538222 — cell biology — Posted on 2023-04-26
693 Ebola Virus Sequesters IRF3 in Viral Inclusion Bodies to Evade Host Antiviral Immunity
Zhu, L.; Jin, J.; Wang, T.; Hu, Y.; Liu, H.; Gao, T.; Dong, Q.; Jin, Y.; Li, P.; Liu, Z.; Liu, X.; Cao, C.
10.1101/2023.04.20.537734 — microbiology — Posted on 2023-04-26
695 Exercise improved P2Y12-regulated microglial dynamics during stroke via endocannabinoid signaling
He, X.-f.; Zhao, Y.; Li, G.; Luo, J.; Xu, J.-h.; Zheng, H.-q.; Zhang, L.-y.; Hu, X.-q.
10.1101/2023.04.24.538065 — neuroscience — Posted on 2023-04-26
696 Large Data on the Small Brain: Population-wide Cerebellar Growth Models of Children and Adolescents
Gaiser, C.; van der Vliet, R.; de Boer, A. A. A.; Donchin, O.; Berthet, P.; Devenyi, G. A.; Chakravarty, M.; Diedrichsen, J.; Marquand, A. F.; Frens, M. A.; Muetzel, R. L.
10.1101/2023.04.26.538263 — neuroscience — Posted on 2023-04-26
697 Brain network flexibility as a predictor of skilled musical performance
Uehara, K.; Yasuhara, M.; Koguchi, J.; Oku, T.; Shiotani, S.; Morise, M.; Furuya, S.
10.1101/2023.04.26.538360 — neuroscience — Posted on 2023-04-26
698 REVEILLE2 Thermosensitive Splicing: A Molecular Basis for the Integration of Nocturnal Temperature Information by the Arabidopsis Circadian Clock
James, A. B.; Sharples, C.; Laird, J.; Armstrong, E. M.; Guo, W.; Tzioutziou, N.; Zhang, R.; Brown, J. W.; Nimmo, H. G.; Jones, M. A.
10.1101/2023.04.24.538045 — plant biology — Posted on 2023-04-26
699 Chemotactic interactions drive migration of membraneless active droplets
Dindo, M.; Bevilacqua, A.; Soligo, G.; Monti, A.; Rosti, M.; Laurino, P.
10.1101/2023.04.25.538216 — biochemistry — Posted on 2023-04-26
700 Phylogenomics reveals incomplete lineage sorting and ancient hybrid drove the radiation of macaques
Tan, X.; Qi, J.; Liu, Z.; Fan, P.; Liu, G.; Zhang, L.; Shen, Y.; Li, J.; Roos, C.; Zhou, X.; Li, M.
10.1101/2023.01.09.523240 — evolutionary biology — Posted on 2023-04-26
701 Molecular insight into the enzymatic macrocyclization of multiply backbone N-methylated peptides
Matabaro, E.; Song, H.; Gherlone, F.; Sonderegger, L.; Giltrap, A.; Liver, S.; Gossert, A.; Künzler, M.; Naismith, J. H.
10.1101/2022.07.21.500988 — biochemistry — Posted on 2023-04-26
704 TemStaPro: protein thermostability prediction using sequence representations from protein language models
Pudziuvelyte, I.; Olechnovic, K.; Godliauskaite, E.; Sermokas, K.; Urbaitis, T.; Gasiunas, G.; Kazlauskas, D.
10.1101/2023.03.27.534365 — bioinformatics — Posted on 2023-04-26
705 Mobilisation and analyses of publicly available SARS-CoV-2 data for pandemic responses
Rahman, N.; O'Cathail, C.; Zyoud, A.; Sokolov, A.; Oude Munnink, B.; Grüning, B. A.; Cummins, C.; Amid, C.; Nieuwenhuijse, D. F.; Visontai, D.; Yuan, D. Y.; Gupta, D.; Prasad, D.; Gulyas, G. M.; Rinck, G.; McKinnon, J.; Rajan, J.; Knaggs, J.; Skiby, J. E.; Steger, J.; Szarvas, J.; Gueye, K.; Papp, K.; Hoek, M.; Kumar, M.; Ventouratou, M. A.; Bouquieaux, M.-C.; Koliba, M.; Mansurova, M.; Haseeb, M.; Worp, N.; Harrison, P. W.; Leinonen, R.; Thorne, R.; Selvakumar, S.; Hunt, S.; Venkataraman, S.; Jayathilaka, S.; Cezard, T.; Maier, W.; Waheed, Z.; Iqbal, Z.; Aarestrup, F. M.; Csabai, I.; Koopman
10.1101/2023.04.19.537514 — bioinformatics — Posted on 2023-04-26
706 Selection on many loci drove the origin and spread of a key innovation
Stankowski, S.; Zagrodzka, Z. B.; Garlovsky, M. D.; Pal, A.; Shipilina, D.; Garcia Castillo, D. F.; Le Moan, A.; Leder, E.; Reeve, J.; Johannesson, K.; Westram, A.; Butlin, R. K.
10.1101/2023.02.13.528213 — evolutionary biology — Posted on 2023-04-26
709 Neurogenomic landscape of status-dependent cooperative behavior
Bolton, P. E.; Ryder, T. B.; Dakin, R.; Houtz, J. L.; Moore, I. T.; Balakrishnan, C. N.; Horton, B. M.
10.1101/2022.10.05.510848 — evolutionary biology — Posted on 2023-04-26
711 Regulation of Store-Operated Ca2+ Entry by IP3 Receptors Independent of Their Ability to Release Ca2+
Chakraborty, P.; Deb, B. K.; Arige, V.; Musthafa, T.; Malik, S.; Yule, D. I.; Taylor, C. W.; Hasan, G.
10.1101/2022.04.12.488111 — cell biology — Posted on 2023-04-26
715 Root branching in salt requires auxin-independent modulation of LBD16 function
Zhang, Y.; Li, Y.; De Zeeuw, T.; Duijts, K.; Kawa, D.; Lamers, J.; Munzert, K. S.; Li, H.; Zou, Y.; Meyer, A. J.; Yan, J.; Verstappen, F.; Wang, Y.; Gijsberts, T.; Wang, J.; Gigli-Bisceglia, N.; Engelsdorf, T.; van Dijk, A. D. J.; Testerink, C.
10.1101/2023.04.25.538210 — plant biology — Posted on 2023-04-26
717 Introgression underlies phylogenetic uncertainty but not parallel plumage evolution in a recent songbird radiation
Rancilhac, L.; Enbody, E. D.; Harris, R.; Saitoh, T.; Irestedt, M.; Liu, Y.; Lei, F.; Andersson, L.; Alstrom, P.
10.1101/2023.04.25.538255 — evolutionary biology — Posted on 2023-04-26
723 A Nanoparticle RIG-I Agonist for Cancer Immunotherapy
Wang-Bishop, L.; Wehbe, M.; Pastora, L. E.; Yang, J.; Garland, K. M.; Becker, K. W.; Carson, C. S.; Gibson-Corley, K. N.; Ulkoski, D.; Krishnamurthy, V.; Fedorova, O.; Richmond, A.; Pyle, A. M.; Wilson, J. T.
10.1101/2023.04.25.537919 — bioengineering — Posted on 2023-04-25
724 Primary Ciliary Dyskinesia patient specific hiPSC-derived airway epithelium in Air Liquid Interface culture recapitulates disease specific phenotypes in vitro
von Schledorn, L.; Martin, D. P.; Cleve, N.; Zoellner, J.; Roth, D.; Staar, B. O.; Hegermann, J.; Ringshausen, F.; Nawroth, J. C.; Martin, U.; Olmer, R.
10.1101/2023.04.25.538316 — bioengineering — Posted on 2023-04-25
725 Chemotactic interactions drive migration ofmembraneless active droplets
Dindo, M.; Bevilacqua, A.; Soligo, G.; Monti, A.; rosti, m.; Laurino, P.
10.1101/2023.04.25.538216 — biochemistry — Posted on 2023-04-25
728 Novel Chromatin Insulating Activities Uncovered upon Eliminating KnownInsulators in vivo
Ortabozkoyun, H.; Huang, P.-Y.; Cho, H.; Mazzoni, E.; Tsirigos, A.; Reinberg, D.
10.1101/2023.04.25.538167 — genetics — Posted on 2023-04-25
729 A machine vision guided robot for fully automated embryonic microinjection
Alegria, A. D.; Joshi, A. S.; Mendana, J. B.; Khosla, K.; Smith, K.; Auch, B. T.; Donovan, M.; Bischof, J.; Gohl, D.; Kodandaramaiah, S. B.
10.1101/2023.04.25.538280 — genetics — Posted on 2023-04-25
731 Boosting N-terminally anchored yeast surface display via structural insights into S. cerevisiae Pir proteins
Martinic Cezar, T.; Lozancic, M.; Novacic, A.; Maticevic, A.; Matijevic, D.; Vallee, B.; Mrsa, V.; Teparic, R.; Zunar, B.
10.1101/2023.04.25.538238 — molecular biology — Posted on 2023-04-25
735 ZBP1-mediated macrophage necroptosis inhibits ASFV replication
Zhang, K.; Hao, Y.; Yang, B.; Yang, J.; Zhang, D.; Yang, X.; Shi, X.; Zhao, D.; Chen, L.; Yan, W.; Ru, Y.; Zhu, Z.; Qin, X.; Liu, H.-N.; Yang, F.; Li, D.; Tian, H.; Feng, T.; Guo, J.; He, J.; Liu, X.-T.; Zheng, H.
10.1101/2023.04.25.538262 — microbiology — Posted on 2023-04-25
736 Synaptopodin is necessary for Shigella flexneri intercellular spread
Vickery, J. M.; Toperzer, J. D.; Raab, J. E.; Lenz, L. L.; Colgan, S. P.; Russo, B. C.
10.1101/2023.04.25.537990 — microbiology — Posted on 2023-04-25
737 Superior Efficacy of Combination Antibiotic Therapy versus Monotherapy in a Mouse Model of Lyme Disease
Embers, M. E.; Alruwaili, Y.; Hasenkampf, N. R.; Jacobs, M. B.; Tardo, A. C.; McDaniel, C.
10.1101/2023.04.25.538305 — microbiology — Posted on 2023-04-25
738 Quantifying Rift Valley fever virus transmission efficiency in a lamb-mosquito-lamb model
Bron, G.; Wichgers-Schreur, P.; de Jong, M. C. M.; van Keulen, L.; Vloet, R. P. M.; Koenraadt, C. J. M.; Kortekaas, J.; ten Bosch, Q.
10.1101/2023.04.25.538218 — microbiology — Posted on 2023-04-25
739 B cells from aged mice do not have intrinsic defects in affinity maturation
Lee, J. L.; Innocentin, S.; Silva-Cayetano, A.; Guillaume, S.; Linterman, M. A.
10.1101/2023.04.24.538044 — immunology — Posted on 2023-04-25
743 AadT, a new weapon in Acinetobacters fight against antibiotics
Naidu, V. N.; Shah, B.; Maher, C.; Paulsen, I. T.; Hassan, K. A.
10.1101/2023.01.03.522653 — microbiology — Posted on 2023-04-25
748 Decoding optimal ligand design for multicomponent condensates
Galagedera, S. K. K.; Dao, T. P.; Enos, S. E.; Chaudhuri, A.; Schmit, J. D.; Castaneda, C. A.
10.1101/2023.03.13.532222 — biophysics — Posted on 2023-04-25
749 Delineating mouse β-cell identity during lifetime and in diabetes with a single cell atlas
Hrovatin, K.; Bastidas-Ponce, A.; Bakhti, M.; Zappia, L.; Buttner, M.; Sallino, C.; Sterr, M.; Bottcher, A.; Migliorini, A.; Lickert, H.; Theis, F. J.
10.1101/2022.12.22.521557 — bioinformatics — Posted on 2023-04-25
750 3D structural human interactome reveals proteome-wide perturbations by disease mutations
Xiong, D.; Zhao, J.; Qiu, Y.; Zhou, Y.; Lee, D.; Gupta, S.; Lu, W.; Liang, S.; Kang, J. J.; Eng, C.; Loscalzo, J.; Cheng, F.; Yu, H.
10.1101/2023.04.24.538110 — bioinformatics — Posted on 2023-04-25
753 A high-performance speech neuroprosthesis
Willett, F. R.; Kunz, E.; Fan, C.; Avansino, D.; Wilson, G.; Choi, E. Y.; Kamdar, F.; Hochberg, L. R. H.; Druckmann, S.; Shenoy, K.; Henderson, J.
10.1101/2023.01.21.524489 — neuroscience — Posted on 2023-04-25
758 The ins and outs of membrane bending by intrinsically disordered proteins
Yuan, F.; Lee, C. T.; Sangani, A.; Houser, J.; Wang, L.; Lafer, E.; Rangamani, P.; Stachowiak, J.
10.1101/2022.12.17.520884 — biophysics — Posted on 2023-04-25
760 CellNeighborEX: Deciphering Neighbor-Dependent Gene Expression from Spatial Transcriptomics Data
Kim, H.; Lövkvist, C.; Palma, A. M.; Martin, P. C. N.; Kim, J.; Kumar, A.; Peixoto, M. L.; Madan, E.; Gogna, R.; Won, K. J.
10.1101/2022.02.16.480673 — bioinformatics — Posted on 2023-04-25
761 The vascularised chamber device significantly enhances the survival of transplanted liver organoids
Shi, D. D.; Makris, E.; Gerrand, Y.-W.; Lo, P.-H.; Yeoh, G. C.; Morrison, W. A.; Mitchell, G. M.; Yap, K. K.
10.1101/2023.04.24.538062 — bioengineering — Posted on 2023-04-25
773 LoxCode in vivo clonal barcoding resolves mammalian epiblast contribution to fetal organs
Weber, T. S.; Biben, C.; Miles, D. C.; Glaser, S.; Tomei, S.; Zhang, S.; Tam, P.; Taoudi, S.; Naik, S. H.
10.1101/2023.01.02.522501 — developmental biology — Posted on 2023-04-25
775 SARS-CoV-2 Spike Protein Reduces Burst Activities in Neurons Measured by Micro-Electrode Arrays
Salvador, M.; Tseng, N.; Park, C.; Williams, G.; Vethan, A.; Thomas, G.; Baker, J.; Hemry, J.; Hammond, E.; Freeburg, P.; Chou, G.-W.; Taylor, N.; Lu, Y.-F.
10.1101/2023.04.24.538161 — microbiology — Posted on 2023-04-25
782 Class I histone deacetylase complex: structure and functional correlates
Wang, X.; Wang, Y.; Liu, S.; Zhang, Y.; Xu, K.; Ji, L.; Kornberg, R.; Zhang, H.
10.1101/2023.04.24.538028 — biophysics — Posted on 2023-04-25
787 Chaotic aging: Intrinsically disordered proteins in aging-related processes
Manyilov, V. D.; Ilyinsky, N. S.; Nesterov, S. V.; Saqr, B. M. G. A.; Dayhoff, G. W.; Zinovev, E. V.; Matrenok, S. S.; Fonin, A. V.; Kuznetsova, I. M.; Turoverov, K. K.; Gordeliy, V. I.; Uversky, V. N.
10.1101/2023.04.22.537928 — bioinformatics — Posted on 2023-04-25
792 How Do Deer Respiratory Epithelial Cells Weather The Initial Storm of SARS-CoV-2?
Davila, K. M. S.; Nelli, R. K.; Phadke, K. S.; Ruden, R. M.; Sang, Y.; Bellaire, B. H.; Gimenez-Lirola, L. G.; Miller, L. C.
10.1101/2023.04.24.538130 — genomics — Posted on 2023-04-25
793 A multiplexed RT-PCR Assay for Nanopore Whole Genome Sequencing of Tilapia lake virus (TiLV)
Delamare-Deboutteville, J.; Watcharachai, M.; Gan, H. M.; Mohan, C. V.; Dong, H. T.; Senapin, S.
10.1101/2023.04.24.537954 — genomics — Posted on 2023-04-25
794 Migration in uncertain times
Jaggi, H.; Steinsaltz, D.; Tuljapurkar, S.
10.1101/2023.04.23.537980 — ecology — Posted on 2023-04-25
799 Contribution of the IGCR1 regulatory element and the 3'Igh CBEs to Regulation of Igh V(D)J Recombination
Liang, Z.; Zhao, L.; Ye, A. Y.; Lin, S. G.; Zhang, Y.; Guo, C.; Dai, H.-Q.; Ba, Z.; Alt, F. W.
10.1101/2023.04.21.537836 — immunology — Posted on 2023-04-25
800 Non-canonical D1-D2 rearrangements are bimodal and represent a conservative hidden stage of VDJ recombination in TCR beta locus
Smirnova, A. O.; Miroshnichenkova, A. M.; Belyaeva, L. D.; Kelmanson, I. V.; Lebedev, Y. B.; Mamedov, I. Z.; Chudakov, D. M.; Komkov, A. Y.
10.1101/2023.04.21.537904 — immunology — Posted on 2023-04-25
801 IL-15 priming alters IFN-γ regulation in murine NK cells
Cimpean, M.; Keppel, M. P.; Gainullina, A.; Fan, C.; Schedler, N. C.; Swain, A.; Kolicheski, A.; Shapiro, H.; Young, H. A.; Wang, T.; Artyomov, M.; Cooper, M. A.
10.1101/2023.04.23.537947 — immunology — Posted on 2023-04-25
802 Inosine Induces Stemness Features in CAR T cells and Enhances Potency
Klysz, D. D.; Fowler, C.; Malipatlolla, M.; Stuani, L.; Freitas, K. A.; Meier, S.; Daniel, B.; Sandor, K.; Xu, P.; Huang, J.; Labanieh, L.; Leruste, A.; Bashti, M.; Keerthi, V.; Mata-Alcazar, J.; Gkitsas, N.; A. Guerrero, J.; Fisher, C.; Patel, S.; Asano, K.; Patel, S.; L. Davis, K.; Satpathy, A. T.; Feldman, S. A.; Sotillo, E.; Mackall, C. L.
10.1101/2023.04.21.537859 — immunology — Posted on 2023-04-25
803 The stem cell-type transcriptome of bioenergy sorghum reveals the spatial regulation of secondary cell wall networks
Fu, J.; McKinley, B.; James, B.; Chrisler, W.; Markillie, L. M.; Gaffrey, M. J.; Mitchell, H. D.; Orr, G.; Swaminathan, K.; Mullet, J.; Marshall-Colon, A.
10.1101/2023.04.22.537921 — plant biology — Posted on 2023-04-25
809 Retrospective model utilizing biopsies, granulosa cells, and polar body to predict oocyte competence in bovine
Ambrizi, D. R.; Camara De Bem, T. H.; Nociti, R. P.; Puttini Paixao, J. V.; Chiaratti, M. R.; Sangalli, J. R.; Da Silveira, J. C.; Perecin, F.; de Mattos Oliveira, E. C.; Sterman Ferraz, J. B.; Therrien, J.; Smith, L. C.; Meirelles, F. V.
10.1101/2023.04.23.537973 — genomics — Posted on 2023-04-25
810 A mechanism that integrates microtubule motors of opposite polarity at the kinetochore corona
Cmentowski, V.; D'Amico, E.; Ciossani, G.; Wohlgemuth, S.; Owa, M.; Dynlacht, B. D.; Musacchio, A.
10.1101/2023.04.25.538277 — cell biology — Posted on 2023-04-25
812 An energy costly architecture of neuromodulators for human brain evolution and cognition
Castrillon, G.; Epp, S.; Bose, A.; Fraticelli, L.; Hechler, A.; Belenya, R.; Ranft, A.; Yakushev, I.; Utz, L.; Sundar, L. K. S.; Rauschecker, J.; Preibisch, C.; Kurcyus, K.; Riedl, V.
10.1101/2023.04.25.538209 — neuroscience — Posted on 2023-04-25
814 Direction-dependent neural control of finger dexterity in humans
Rajchert, O.; Ofir-Geva, S.; Melul, Y.; Khoury-Mireb, M.; Wonderman Bar-Sela, O.; Granot, O.; Caspi, T.; Frenkel-Toledo, S.; Soroker, N.; Mawase, F.
10.1101/2023.04.25.538234 — neuroscience — Posted on 2023-04-25
817 The Cyclimids: Degron-inspired cereblon binders for targeted protein degradation
Ichikawa, S.; Payne, N. C.; Xu, W.; Chang, C.-F.; Vallavoju, N.; Frome, S.; Flaxman, H. A.; Mazitschek, R.; Woo, C. M.
10.1101/2023.04.22.537935 — biochemistry — Posted on 2023-04-25
821 Root branching in salt requires auxin-independent modulation of LBD16 function
Zhang, Y.; Li, Y.; De Zeeuw, T.; Duijts, K.; Kawa, D.; Lamers, J.; Munzert, K. S.; Li, H.; Zou, Y.; Meyer, A. J.; Yan, J.; Verstappen, F.; Wang, Y.; Gijsberts, T.; Wang, J.; Gigli-Bisceglia, N.; Engelsdorf, T.; van Dijk, A. D. J.; Testerink, C.
10.1101/2023.04.25.538210 — plant biology — Posted on 2023-04-25
824 Turicibacterales protect mice from severe Citrobacter rodentium infection
Hoek, K. L.; McClanahan, K. G.; Latour, Y. L.; Shealy, N.; Piazuelo, M. B.; Vallance, B. A.; Byndloss, M. X.; Olivares-Villagomez, D.; Wilson, K. T.
10.1101/2023.04.25.538270 — microbiology — Posted on 2023-04-25
827 Genomic mechanisms and consequences of diverse postzygotic barriers between monkeyflower species
Sotola, V. A.; Berg, C. S.; Samuli, M.; Chen, H.; Mantel, S. J.; Beardsley, P. A.; Yuan, Y.-W.; Sweigart, A.; Fishman, L.
10.1101/2023.04.21.537885 — genetics — Posted on 2023-04-25
829 Microbiome diversity: A barrier to the environmental spread of antimicrobial resistance?
Klümper, U.; Gionchetta, G.; Catao, E. C.; Bellanger, X.; Dielacher, I.; Fang, P.; Galazka, S.; Goryluk-Salmonowicz, A.; Kneis, D.; Okoroafor, U.; Radu, L.-E.; Szadziul, M.; Szekeres, E.; Teban-Man, A.; Coman, C.; Kreuzinger, N.; Popowska, M.; Vierheilig, J.; Walsh, F.; Woegerbauer, M.; Bürgmann, H.; Merlin, C.; Berendonk, T. U.
10.1101/2023.03.30.534382 — microbiology — Posted on 2023-04-25
830 Optimized replication of arrayed bacterial mutant libraries increase access to biological resources
Willett, J.; Barnes, A. M.; Brunson, D. N.; Lecomte, A.; Robertson, E. B.; Dunny, G. M.
10.1101/2023.04.25.537918 — microbiology — Posted on 2023-04-25
831 ATR2Cala2 from Arabidopsis-infecting downy mildew requires 4 TIR-NLR immune receptors for full recognition
Kim, D. S.; Woods-Tör, A.; Cevik, V.; Furzer, O. J.; Li, Y.; Ma, W.; Tör, M.; Jones, J. D.
10.1101/2023.04.25.538220 — plant biology — Posted on 2023-04-25
833 A spatially resolved single cell genomic atlas of the adult human breast
Kumar, T.; Nee, K.; Wei, R.; He, S.; Nguyen, Q.; Bai, S.; Blake, K.; Pein, M.; Gong, Y.; Sei, E.; Hu, M.; Casasent, A.; Thennavan, A.; Li, J.; Tran, T.; Chen, K.; Nilges, B.; Kashikar, N.; Braubach, O.; Cheikh, B.; Nikulina, N.; Chen, H.; Teshome, M.; Menegaz, B.; Javaid, H.; Nagi, C.; Montalvan, J.; Lev, T.; Tifrea, D.; Edwards, R.; Lin, E.; Parajuli, R.; Hanson, S.; Winocour, S.; Thompson, A.; Lim, B.; Lawson, D.; Kessenbrock, K.; Navin, N.
10.1101/2023.04.22.537946 — genomics — Posted on 2023-04-25
834 Life history diversity in a large group of chloroviruses
Lievens, E. J.; Agarkova, I. V.; Dunigan, D. D.; Van Etten, J. L.; Becks, L.
10.1101/2022.03.13.484168 — evolutionary biology — Posted on 2023-04-25
835 Cryo-electron tomography of NLRP3-activated ASC complexes reveals organelle co-localization
Liu, Y.; Zhai, H.; Alemayehu, H.; Boulanger, J.; Hopkins, L. J.; Borgeaud, A. C.; Heroven, C.; Howe, J. D.; Leigh, K. E.; Bryant, C. E.; Modis, Y.
10.1101/2021.09.20.461078 — immunology — Posted on 2023-04-25
836 Is resting state fMRI better than individual characteristics at predicting cognition?
Omidvarnia, A.; Sasse, L.; Larabi, D. I.; Raimondo, F.; Hoffstaedter, F.; Kasper, J.; Dukart, J.; Petersen, M.; Cheng, B.; Thomalla, G.; Eickhoff, S. B.; Patil, K. R.
10.1101/2023.02.18.529076 — neuroscience — Posted on 2023-04-25
840 Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation
Juyoux, P.; Galdadas, I.; Gobbo, D.; von Velsen, J.; Pelosse, M.; Tully, M.; Vadas, O.; Gervasio, F. L.; Pellegrini, E.; Bowler, M. W.
10.1101/2022.07.04.498667 — biophysics — Posted on 2023-04-25
842 The unique synaptic circuitry of specialized olfactory glomeruli in Drosophila melanogaster
Gruber, L.; Cantera, R.; Pleijzier, M. W.; Steinert, M.; Pertsch, T.; Hansson, B. S.; Rybak, J.
10.1101/2022.09.30.510181 — neuroscience — Posted on 2023-04-25
843 Multi-Omics Data of Perturbation Studies are Determined by Memory Effects from Subculture
Bortel, P.; Hagn, G.; Skos, L.; Bileck, A.; Paulitschke, V.; Paulitschke, P.; Gleiter, L.; Mohr, T.; Gerner, C.; Meier-Menches, S.
10.1101/2023.02.13.528316 — systems biology — Posted on 2023-04-25
844 The E-cadherin-ESR1-GRPR axis defines a sex-specific metastatic pathway in melanoma
Raymond, J. H.; Schonau, M.; Petit, V.; Aktary, Z.; Luciani, F.; Wehbe, M.; Davidson, I.; Tomasetto, C.-L.; Mahuteau-Betzer, F.; Vergier, B.; Larue, L.; Delmas, V.
10.1101/2022.12.02.518844 — cancer biology — Posted on 2023-04-25
846 Transcription bodies regulate gene expression by sequestering CDK9
Ugolini, M.; Kuznetsova, K.; Oda, H.; Kimura, H.; Vastenhouw, N. L.
10.1101/2022.11.21.517317 — cell biology — Posted on 2023-04-25
847 PRE-INJURY MECHANORECEPTOR ABLATION REDUCES NOCICEPTOR-DRIVEN SPINAL CORD INJURY-INDUCED NEUROPATHIC PAIN
Sliwinski, C.; Heutehaus, L.; Taberner, F. J.; Weiss, L.; Kampanis, V.; Tolou-Dabbaghian, B.; Cheng, X.; Motsch, M.; Heppenstall, P. A.; Kuner, R.; Franz, S.; Lechner, S. G.; Weidner, N.; Puttagunta, R.
10.1101/2022.12.18.520950 — neuroscience — Posted on 2023-04-25
848 Transcriptome Analysis Reveals Organ-Specific Effects of 2-Deoxyglucose Treatment in Healthy Mice
Wells, A. E.; Wilson, J. J.; Sears, J. D.; Wei, J.; Heuer, S.; Pandey, R.; Costa, M. W.; Roopenian, D. C.; Chang, C.-H.; Carter, G. W.
10.1101/2023.04.24.537717 — systems biology — Posted on 2023-04-25
850 Dynamics of the epigenetic landscape during development and in response to drought stress in sorghum
Hu, Y.; He, C.; Shen, Y.; Zeng, G.; Bi, S.; Huang, Q.; Qin, X.; Deng, Z.; He, Z.; Shen, X.
10.1101/2023.04.24.537601 — plant biology — Posted on 2023-04-25
853 DLL4-Notch3-WNT5B axis is a novel mediator of bi-directional pro-metastatic crosstalk between melanoma and lymphatic endothelial cells
Alve, S.; Gramolelli, S.; Jukonen, J.; Juteau, S.; Pink, A.; Manninen, A.; Monto, E.; Lackman, M. H.; Carpen, O.; Karaman, S.; Saharinen, P.; Vaahtomeri, K.; Ojala, P. M.
10.1101/2023.04.21.537773 — cancer biology — Posted on 2023-04-25
855 Evaluating the efficiency and accuracy of a commercial test for estimating genetic risk of bovine congestive heart failure
Carlson, J. M.; Heaton, M. P.; Allison, N.; Hangman, A.; Petrik, D.; Piscatelli, H.; Vander Ley, B. L.
10.1101/2023.04.24.536588 — genetics — Posted on 2023-04-25
856 A major myna problem; invasive predator removal benefits female survival and population growth of a translocated island endemic
Brown, T. J.; Hellicar, M.; Accouche, W.; van de Woude, J.; Dugdale, H.; Komdeur, J.; Richardson, D. S.
10.1101/2023.04.22.537650 — ecology — Posted on 2023-04-25
861 TUMOR ENDOTHELIAL CELL AUTOPHAGY IS A KEY VASCULAR-IMMUNE CHECKPOINT IN MELANOMA
Verhoeven, J.; Jacobs, K. A.; Rizzollo, F.; Lodi, F.; Hua, Y.; Pozniak, J.; Srinvasan, A. N.; Houbaert, D.; Shankar, G.; More, S.; Schaaf, M. B.; Dubroja Lakic, N.; Ganne, M.; Lamote, J.; Van Weyenbergh, J.; Boon, L.; Bechter, O.; Bosisio, F.; Bertrand, M.; Marine, J. C.; Lambrechts, D.; Bergers, G.; Agrawal, M.; Agostinis, P.
10.1101/2023.04.21.537799 — cancer biology — Posted on 2023-04-25
862 Inhibitor-based modulation of huntingtin aggregation reduces fibril toxicity
Jain, G.; Trombetta-Lima, M.; Matlahov, I.; Taborda Ribas, H.; Dolga, A. M.; van der Wel, P. C. A.
10.1101/2023.04.24.537565 — biophysics — Posted on 2023-04-25
867 hipFG: High-throughput harmonization and integration pipeline for functional genomics data
Cifello, J.; Kuksa, P. P.; Saravanan, N.; Valladares, O.; Leung, Y. Y.; Wang, L.-S.
10.1101/2023.04.21.537695 — bioinformatics — Posted on 2023-04-25
868 At-home saliva sampling in healthy adults using CandyCollect, a lollipop-inspired device
Tu, W.-c.; McManamen, A. M.; Su, X.; Jeacopello, I.; Takezawa, M. G.; Hieber, D. L.; Hassan, G. W.; Lee, U. N.; Anana, E. V.; Locknane, M. P.; Stephenson, M. W.; Shinkawa, V. A. M.; Wald, E. R.; DeMuri, G. P.; Adams, K.; Berthier, E.; Thongpang, S.; Theberge, A. B.
10.1101/2023.01.14.524039 — biochemistry — Posted on 2023-04-25
870 Genomic Changes During the Evolution of the Coxiella Genus Along the Parasitism-Mutualism Continuum.
Santos-Garcia, D.; Morel, O.; Henri, H.; El Filali, A.; Buysse, M.; Noël, V.; McCoy, K. D.; Gottlieb, Y.; Klasson, L.; Zenner, L.; Duron, O.; Vavre, F.
10.1101/2022.10.26.513839 — microbiology — Posted on 2023-04-25
872 Next Generation Nanopore Sensors for Enhanced Detection of Nanoparticles
Confederat, S.; Lee, S.; Vang, D.; Soulias, D.; Marcuccio, F.; Peace, T. I.; Edwards, M. A.; Strobbia, P.; Samanta, D.; Walti, C.; Actis, P.
10.1101/2023.03.31.534385 — biophysics — Posted on 2023-04-25
877 PhIP-Seq uncovers novel autoantibodies and unique endotypes in interstitial lung disease
Upadhyay, V.; Yoon, Y. m.; Vazquez, S. E.; Velez, T. E.; Jones, K. D.; Lee, C. T.; Law, C. S.; Wolters, P. J.; Lee, S.; Yang, M. M.; Farrand, E.; Noth, I.; Strek, M. E.; Anderson, M.; DeRisi, J.; Sperling, A. I.; Shum, A. K.
10.1101/2023.04.24.538091 — molecular biology — Posted on 2023-04-24
878 Integrated multi-omics approach reveals the role of SPEG in skeletal muscle biology including its relationship with myospryn complex
Li, Q.; Lin, J.; Luo, S.; Schmitz-Abe, K.; Agrawal, R.; Meng, M.; Moghadaszadeh, B.; Beggs, A. H.; Liu, X.; Perrella, M. A.; Agrawal, P. B.
10.1101/2023.04.24.538136 — molecular biology — Posted on 2023-04-24
879 Interferon-gamma Elicits Pathological Hallmarks of ALS in Human Motor Neurons
Chun, C.; Lee, J. H.; Bothwell, M.; Nghiem, P.; Smith, A. S. T.; Mack, D. L.
10.1101/2022.11.18.517141 — neuroscience — Posted on 2023-04-25
880 Dysregulated expression of Hoxa1 isoforms in hematopoietic stem and progenitor cells causes myelodysplastic syndromes.
Tan, S. Y.; Joseph, C.; Chalk, A.; Hendy, J.; Fabb, S.; Schleibs, K.; Lee, S.; Tjin, G.; Grace, C.; Madugalle, V.; Smeets, M. F.; Maluenda, A.; Rice, K.; Baker, E.; Nandurkar, H.; Slape, C.; Parker, M.; Unnikrishnan, A.; Mufti, G.; Tobiasson, M.; Hellstrom-Lindberg, E.; Pimanda, J.; Gudas, L.; Holien, J.; Walkley, C.; Wall, M.; Purton, L.
10.1101/2023.04.24.538176 — cancer biology — Posted on 2023-04-24
881 Disease associated mutations in tau encode for changes in aggregate structure conformation
Sun, K.; Patel, T.; Kang, S.-G.; Yarahmady, A.; Julien, O.; Heras, J.; Mok, S.-A.
10.1101/2023.04.24.537889 — biochemistry — Posted on 2023-04-24
882 A crucial role for dynamic expression of components encoding the negative arm of the circadian clock
Wang, B.; Zhou, X.; Kettenbach, A. N.; Mitchell, H. D.; Markillie, L. M.; Loros, J. J.; Dunlap, J. C.
10.1101/2023.04.24.538162 — biochemistry — Posted on 2023-04-24
883 Isoform-specific C-terminal phosphorylation drives autoinhibition of Casein Kinase 1
Harold, R. L.; Tulsian, N. K.; Narasimamurthy, R.; Yaitanes, N.; Hernandez, M. G. A.; Lee, H.-W.; Virshup, D. M.; Partch, C. L.
10.1101/2023.04.24.538174 — biochemistry — Posted on 2023-04-24
885 A guide to the in vitro reconstitution of Cdc42 GTPase activity and its regulation
Tschirpke, S.; van Opstal, F.; van der Valk, R.; Daalman, W. K.-G.; Laan, L.
10.1101/2023.04.24.538075 — biochemistry — Posted on 2023-04-24
895 Rapid dissemination of host-metabolism-manipulating transposon-like entities via integrative and conjugative elements
Colombi, E.; Bertels, F.; Doulcier, G.; McConnell, E.; Pichugina, T.; Sohn, K. H.; Straub, C.; McCann, H.; Rainey, P. B.
10.1101/2023.04.24.538000 — microbiology — Posted on 2023-04-24
896 Identification of FacZ as a division site placement factor in Staphylococcus aureus
Bartlett, T. M.; Sisley, T. A.; Mychack, A.; Walker, S.; Baker, R. W.; Rudner, D. Z.; Bernhardt, T. G.
10.1101/2023.04.24.538170 — microbiology — Posted on 2023-04-24
899 c-di-AMP determines the hierarchical organization of bacterial RCK proteins
Rocha, R.; Jorge, J. M. P.; Teixeira-Duarte, C. M.; Figueiredo-Costa, I. R.; Herzberg, C.; Stuelke, J.; Morais-Cabral, J. H.
10.1101/2023.04.24.538052 — microbiology — Posted on 2023-04-24
900 Emergence of resistance to succinate dehydrogenase inhibitor fungicides in Pyrenophora teres f. teres and P. teres f. maculata in Australia
Mair, W. J.; Wallwork, H.; Garrard, T. A.; Haywood, J.; Sharma, N.; Dodhia, K. N.; Oliver, R. P.; Lopez-Ruiz, F. J.
10.1101/2023.04.23.537974 — microbiology — Posted on 2023-04-24
902 Integration of microbial and chemical synthesis for the efficient production of plitidepsin, a promising anticancer and antiviral agent
Zhang, H.; Hui, Z.; Cai, M.; Huang, S.; Shi, W.; Liang, M.; Lin, Y.; Shen, J.; Sui, M.; Li, X.; Lai, Q.; Dou, J.; Ge, Y.; Zheng, M.; Shao, Z.; Lou, X.; Tang, X.
10.1101/2023.04.24.537896 — synthetic biology — Posted on 2023-04-24
903 Mechanism of the Covalent Inhibition of Human Transmembrane Protease Serine 2 as an Original Antiviral Strategy
Spinello, A.; D'Anna, L.; Bignon, E.; Miclot, T.; Grandemange, S.; Terenzi, A.; Barone, G.; Barbault, F.; MONARI, A.
10.1101/2023.04.23.537985 — biophysics — Posted on 2023-04-24
904 The enigma of the SARS-CoV-2 microcirculation dysfunction: evidence for modified endothelial junctions.
Bouillet, L.; Benmarce, M.; Guerin, C.; Bouvet, L.; Garnier, O.; Martin, D.; Vilgrain, I.
10.1101/2023.04.24.538100 — biochemistry — Posted on 2023-04-24
905 SARS-CoV-2 Nonstructural Proteins 3 and 4 tune the Unfolded Protein Response
Davies, J. P.; Sivadas, A.; Keller, K. R.; Wojcikiewicz, R. J.; Plate, L.
10.1101/2023.04.22.537917 — biochemistry — Posted on 2023-04-24
906 Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity
Lei, Y.; Vanportfliet, J. J.; Chen, Y.-F.; Bryant, J. D.; Li, Y.; Fails, D.; Torres Odio, S.; Ragan, K. B.; Deng, J.; Mohan, A.; Wang, B.; Brahms, O.; Yates, S.; Spencer, M.; Tong, C. W.; Bosenberg, M. W.; West, L. C.; Shadel, G. S.; SHUTT, T.; Upton, J. W.; Li, P.; West, A. P.
10.1101/2022.05.30.493783 — immunology — Posted on 2023-04-24
909 Comammox and Unknown Candidate AOBs Contribute to Nitrite Accumulation in An Integrated A-B stage process that Incorporates Side-stream EBPR (S2EBPR)
Yan, Y.; Lee, J.; Han, I.; Wang, Z.; Li, G.; McCullough, K.; Klaus, S.; Kang, D.; Wang, D.; Patel, A.; McQuarrie, J.; Stinson, B. M.; deBarbadillo, C.; Dombrowski, P.; Bott, C.; Gu, A. Z.
10.1101/2023.03.29.534650 — bioengineering — Posted on 2023-04-24
910 Distinct states of nucleolar stress induced by anti-cancer drugs
Potapova, T. A.; Unruh, J. R.; Conkright-Fincham, J. J.; Banks, C. A. S.; Florens, L.; Schneider, D. A.; Gerton, J. L.
10.1101/2022.11.18.517150 — cell biology — Posted on 2023-04-24
911 Metabolic interplay between Proteus mirabilis and Enterococcus faecalis facilitates polymicrobial biofilm formation and invasive disease
Hunt, B. C.; Brix, V.; Vath, J.; Guterman, L. B.; Taddei, S. M.; Learman, B. S.; Brauer, A. L.; Shen, S.; Qu, J.; Armbruster, C. E.
10.1101/2023.03.17.533237 — microbiology — Posted on 2023-04-24
912 Does ipsilateral remapping following hand loss impact motor control of the intact hand?
Tucciarelli, R.; Ejaz, N.; Wesselink, D. B.; Kolli, V.; Hodgetts, C. J.; Diedrichsen, J.; Makin, T.
10.1101/2023.04.19.537443 — neuroscience — Posted on 2023-04-24
915 Next Generation Nanopore Sensors for Enhanced Detection of Nanoparticles
Confederat, S.; Lee, S.; Wang, D.; Soulias, D.; Marcuccio, F.; Peace, T. I.; Edwards, M. A.; Strobbia, P.; Samanta, D.; Walti, C.; Actis, P.
10.1101/2023.03.31.534385 — biophysics — Posted on 2023-04-24
917 Prioritized polycystic kidney disease drug targets and repurposing candidates from pre-cystic and cystic mouse Pkd2 model gene expression reversion
Wilk, E. J.; Howton, T. C.; Fisher, J. L.; Oza, V. H.; Brownlee, R. T.; McPherson, K. C.; Cleary, H. L.; Yoder, B. K.; George, J. F.; Mrug, M.; Lasseigne, B. N.
10.1101/2022.12.02.518863 — genomics — Posted on 2023-04-24
919 Insights for disease modeling from single cell transcriptomics of iPSC-derived Ngn2-induced neurons and astrocytes across differentiation time and co-culture
Das, D.; Sonthalia, S.; Stein-O'Brien, G. G.; Wahbeh, M.; Feuer, K.; Goff, L.; Colantuoni, C.; Machairaki, V.; Avramopoulos, D.
10.1101/2022.06.15.495952 — genetics — Posted on 2023-04-24
921 Isthmus progenitor cells contribute to homeostatic cellular turnover and support regeneration following intestinal injury
Malagola, E.; Vasciaveo, A.; Ochiai, Y.; Kim, W.; Middelhoff, M.; Nienhuser, H.; Belin, B.; LaBella, J.; Zamechek, L.; Wong, M.; Li, L.; Guha, C.; Yan, K.; Califano, A.; Wang, T.
10.1101/2022.04.26.489611 — developmental biology — Posted on 2023-04-24
930 Myocardial IGF2R is a critical mediator of inflammation and fibrosis after ischemia-reperfusion injury
Wu, Z.; Huang, W.; He, X.; Dutta, S.; Paul, C.; Fan, G.-C.; Kanisicak, O.; Xu, M.; Liang, J.; Wang, Y.
10.1101/2023.04.21.537835 — cell biology — Posted on 2023-04-24
931 IGF2BP1/IMP1 deletion enhances a facultative stem cell state via regulation of MAP1LC3B
Parham, L. R.; Williams, P. A.; Chatterji, P.; Acheampong, K.; Danan, C. H.; Katada, K.; Ma, X.; Simon, L. A.; Naughton, K. E.; Mizuno, R.; Karakasheva, T.; McMillan, E. A.; Whelan, K. A.; Brady, D. C.; Shaffer, S. M.; Hamilton, K. E.
10.1101/2022.02.28.482365 — cell biology — Posted on 2023-04-24
932 Disrupting microglial TGF-β signaling triggers region-specific pathology in the spinal cord
Zhu, K.; Min, J.-H.; Joshua, V.; Liu, Y.; Pieber, M.; Suerth, V.; Sarlus, H.; Harris, R.; Lund, H.
10.1101/2023.04.24.538074 — neuroscience — Posted on 2023-04-24
934 standR: a Bioconductor package for analysing transcriptomic Nanostring GeoMx DSP data
Liu, N.; Bhuva, D. D.; Mohamed, A.; Bokelund, M.; Kulasinghe, A.; Tan, C. W.; Davis, M. J.
10.1101/2023.04.23.538017 — bioinformatics — Posted on 2023-04-24
935 BEERS2: RNA-Seq simulation through high fidelity in silico modeling
Brooks, T. G.; Lahens, N. F.; Mrcela, A.; Sarantapoulou, D.; Nayak, S.; Naik, A.; Sengupta, S.; Choi, P. S.; Grant, G. R.
10.1101/2023.04.21.537847 — bioinformatics — Posted on 2023-04-24
937 A spatially resolved single cell genomic atlas of the adult human breast
Kumar, T.; Nee, K.; Wei, R.; He, S.; Nguyen, Q.; Bai, S.; Blake, K.; Pein, M.; Gong, Y.; Sei, E.; Hu, M.; Casasent, A.; Thennavan, A.; Li, J.; Tran, T.; Chen, K.; Nilges, B.; Kashikar, N.; Braubach, O.; Cheikh, B.; Nikulina, N.; Chen, H.; Teshome, M.; Menegaz, B.; Javaid, H.; Nagi, C.; Montalvan, J.; Lev, T.; Tifrea, D.; Edwards, R.; Lin, E.; Parajuli, R.; Hanson, S.; Winocour, S.; Thompson, A.; Lim, B.; Lawson, D.; Kessenbrock, K.; Navin, N.
10.1101/2023.04.22.537946 — genomics — Posted on 2023-04-24
939 On growth and form of the mammary gland: Epithelial-mesenchymal interactions in embryonic mammary gland development
Lan, Q.; Trela, E.; Lindstrom, R.; Satta, J.; Christensen, M. M.; Holzenberger, M.; Jernvall, J.; Mikkola, M. L.
10.1101/2023.04.24.538064 — developmental biology — Posted on 2023-04-24
941 Superior colliculus cell types bidirectionally modulate choice activity in frontal cortex
Thomas, A. M.; Yang, W.; Wang, C.; Tipparaju, S. L.; Chen, G.; Sullivan, B. J.; Swiekatowski, K.; Tatam, M.; Gerfen, C. R.; Li, N.
10.1101/2023.04.22.537884 — neuroscience — Posted on 2023-04-24
942 Neural stem and progenitor cells support and protect adult hippocampal function via vascular endothelial growth factor secretion.
Denninger, J. K.; Miller, L. N.; Walters, A. E.; Hosawi, M.; Sebring, G.; Rieskamp, J. D.; Ding, T.; Rindani, R.; Chen, K. S.; Senthilvelan, S.; Volk, A.; Zhao, F.; Askwith, C.; Kirby, E. D.
10.1101/2023.04.24.537801 — neuroscience — Posted on 2023-04-24
945 State-dependent role of interhemispheric pathway for motor recovery in primates
Mitsuhashi, M.; Yamguchi, R.; Kawasaki, T.; Ueno, S.; Sun, Y.; Isa, K.; Takahashi, J.; Kobayashi, K.; Onoe, H.; Takahashi, R.; Isa, T.
10.1101/2023.04.23.538021 — neuroscience — Posted on 2023-04-24
949 Pathways that affect anterior morphogenesis in C. elegans embryos
Boopathi, B.; Topalidou, I.; Kelley, M.; Meadows, S. M.; Funk, O.; Ailion, M.; Fay, D. S.
10.1101/2023.04.23.537986 — developmental biology — Posted on 2023-04-24
950 Deoxyhypusine synthase is required for the translational regulation of pancreatic beta cell maturation
Connors, C. T.; Anderson-Baucum, E. K.; Rosario, S. R.; Villaca, C. B. P.; Rutan, C. D.; Childress, P. J.; Padgett, L. R.; Robertson, M. A.; Mastracci, T. L.
10.1101/2023.04.24.537996 — developmental biology — Posted on 2023-04-24
953 Learning shapes neural geometry in the prefrontal cortex
Wojcik, M. J.; Stroud, J. P.; Wasmuht, D. F.; Kusunoku, M.; Kadohisa, M.; Myers, N. E.; Hunt, L. T.; Duncan, J.; Stokes, M. G.
10.1101/2023.04.24.538054 — neuroscience — Posted on 2023-04-24
955 Cannabinoid type 2 receptor inhibition enhances the antidepressant and proneurogenic effects of physical exercise after chronic stress
Rodrigues, R. S.; Moreira, J. B.; Vaz, S. H.; Barateiro, A.; Paulo, S. L.; Mateus, J. M.; Lourenco, D. M.; Ribeiro, F. F.; Loureiro-Campos, E.; Bielefeld, P.; Fernandes, A.; Sebastiao, A. M. P.; Pinto, L.; Fitzsimons, C. P.; Xapelli, S.
10.1101/2023.04.24.538087 — neuroscience — Posted on 2023-04-24
956 Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology
Castano, A.; Silvestre, M.; Wells, C. I.; Sanderson, J. L.; Ferrer, C. A.; Ong, H. W.; Lang, Y.; Richardson, W.; Silvaroli, J. A.; Bashore, F. M.; Smith, J. L.; Genereux, I. M.; Dempster, K.; Drewry, D. H.; Pabla, N. S.; Bullock, A. N.; Benke, T. A.; Ultanir, S.; Axtman, A. D.
10.1101/2023.04.24.538049 — neuroscience — Posted on 2023-04-24
958 Leptin activation of dorsal raphe neurons inhibits feeding behavior
Maxwell, N. D.; Smiley, C. E.; Sadek, A. T.; Loyo-Rosado, F. Z.; Giles, D. C.; Macht, V. A.; Woodruff, J. L.; Taylor, D. L.; Wilson, S. P.; Fadel, J. R.; Reagan, L. P.; Grillo, C. A.
10.1101/2023.04.24.538086 — neuroscience — Posted on 2023-04-24
959 Layer 5a Corticostriatal Projection Neurons are Selectively Vulnerable in Huntington's Disease
Pressl, C.; Mätlik, K.; Kus, L.; Darnell, P.; Luo, J.-D.; Weiss, A. R.; Liguore, W.; Carroll, T.; Davis, D. A.; McBride, J.; Heintz, N.
10.1101/2023.04.24.538096 — neuroscience — Posted on 2023-04-24
964 An single oscillating proto-hypothalamic neuron gates taxis behavior in the primitive chordate Ciona
Smith, W.; Chung, J.; Newman-Smith, E.; Kourakis, M. J.; Miao, Y.; Borba, C.; Medina, J.; Laurent, T.; Gallean, B.; Faure, E.
10.1101/2023.04.24.538092 — neuroscience — Posted on 2023-04-24
966 Conserved neural dynamics and computations across species in olfaction
Ling, D.; Hanson Moss, E.; Smith, C. L.; Kroeger, R.; Reimer, J. L.; Raman, B.; Arenkiel, B. R.
10.1101/2023.04.24.538157 — neuroscience — Posted on 2023-04-24
969 Excitatory neuron-specific suppression of the integrated stress response pathway contributes to autism-related phenotypes in a mouse model of fragile X syndrome
Hooshmandi, M.; Sharma, V.; Perez, C. T.; Sood, R.; Simbriger, K.; Wong, C.; Lister, K. C.; Guzman, A. U.; Bartley, T. D.; Rocha, C.; Maussion, G.; Nadler, E.; Roque, P. M.; Gantois, I.; Popic, J.; Levesque, M.; Kaufman, R. J.; Avoli, M.; Sanz, E.; Nader, K.; Hagerman, R. J.; Durcan, T. M.; Costa-Mattioli, M.; Lacaille, J.-C.; Martinez-Cerdeno, V.; Gibson, J. R.; Huber, K.; Sonenberg, N.; Gkogkas, C. G.; Khoutorsky, A.
10.1101/2023.04.24.538123 — neuroscience — Posted on 2023-04-24
970 Response to photic stimulation as a measure of cortical excitability in epilepsy patients
Vranic-Peters, M. J.; O'brien, P.; Seneviratne, U.; Reynolds, A.; Lai, A.; Grayden, D. B.; Cook, M.; Peterson, A.
10.1101/2023.04.23.537976 — neuroscience — Posted on 2023-04-24
972 Infant Left Amygdala Volume Is Negatively Associated with Fecal Microbiota Diversity
Aatsinki, A.-K.; Tuulari, J. J.; Munukka, E. J.; Lahti, L.; Keskitalo, A.; Kailanto, H.-M.; Nolvi, S.; Scheinin, N. M.; Saunavaara, J.; Parkkola, R.; Lewis, J. D.; Hashempour, N.; Shulist, S. J.; Karlsson, L.; Karlsson, H.
10.1101/2023.04.23.537273 — neuroscience — Posted on 2023-04-24
974 DeepComBat: A Statistically Motivated, Hyperparameter-Robust, Deep Learning Approach to Harmonization of Neuroimaging Data
Hu, F.; Lucas, A.; Chen, A. A.; Coleman, K.; Horng, H.; Ng, R. W. S.; Tustison, N. J.; Davis, K. A.; Shou, H.; Li, M.; Shinohara, R. T.
10.1101/2023.04.24.537396 — neuroscience — Posted on 2023-04-24
976 Contextual modulation is a stable feature of the neural code in auditory cortex of awake mice
Akritas, M.; Armstrong, A. G.; Lebert, J. M.; Meyer, A. F.; Sahani, M.; Linden, J. F.
10.1101/2023.04.22.537782 — neuroscience — Posted on 2023-04-24
979 S:D614G and S:H655Y are gateway mutations that act epistatically to promote SARS-CoV-2 variant fitness
Yurkovetskiy, L.; Egri, S.; Kurhade, C.; Diaz-Salinas, M. A.; Jaimes, J. A.; Nyalile, T.; Xie, X.; Choudhary, M. C.; Dauphin, A.; Li, J. Z.; Munro, J. B.; Shi, P.-Y.; Shen, K.; Luban, J.
10.1101/2023.03.30.535005 — microbiology — Posted on 2023-04-24
980 SARS-CoV-2 Infects Peripheral and Central Neurons Before Viremia, Facilitated by Neuropilin-1
Joyce, J. D.; Moore, G. A.; Goswami, P.; Harrell, T. L.; Taylor, T. M.; Hawks, S. A.; Green, J. C.; Jia, M.; Yallayi, N.; Leslie, E. H.; Duggal, N. K.; Thompson, C. K.; Bertke, A. S.
10.1101/2022.05.20.492834 — neuroscience — Posted on 2023-04-24
981 Computationally restoring the potency of a clinical antibody against SARS-CoV-2 Omicron subvariants
Desautels, T. A.; Arrildt, K. T.; Zemla, A. T.; Lau, E. Y.; Zhu, F.; Ricci, D.; Cronin, S.; Zost, S.; Binshtein, E.; Scheaffer, S. M.; Dadonaite, B.; Petersen, B. K.; Engdahl, T. B.; Chen, E.; Handal, L. S.; Hall, L.; Goforth, J. W.; Vashchenko, D.; Nguyen, S.; Weilhammer, D. R.; Lo, J. K.-Y.; Rubinfeld, B.; Saada, E. A.; Weisenberger, T.; Lee, T.-H.; Whitener, B.; Case, J. B.; Ladd, A.; Silva, M. S.; Haluska, R. M.; Grzesiak, E. A.; Earnhart, C. G.; Hopkins, S. A.; Bates, T. W.; Thackray, L. B.; Segelke, B. W.; Lillo, A. M.; Sundaram, S.; Bloom, J. D.; Diamond, M. S.; Crowe, J. E.; Carnahan,
10.1101/2022.10.21.513237 — microbiology — Posted on 2023-04-24
982 Simulating structurally variable Nuclear Pore Complexes for Microscopy
Theiss, M.; Heriche, J.-K.; Russell, C.; Helekal, D.; Soppitt, A.; Ries, J.; Ellenberg, J.; Brazma, A.; Uhlmann, V.
10.1101/2022.05.17.492295 — bioinformatics — Posted on 2023-04-24
984 Extensive re-modelling of the cell wall during the development of Staphylococcus aureus bacteraemia
Douglas, E. J. A.; Palk, N.; Brignoli, T.; Altwiley, D.; Boura, M.; Laabei, M.; Recker, M.; Cheung, G. C.; Liu, R.; Hseih, R. C.; Otto, M.; O'Brien, E.; McLoughlin, R. M.; Massey, R. C.
10.1101/2023.02.23.529713 — microbiology — Posted on 2023-04-24
985 CNC Knitting Micro-Resolution Mosquito Bite Blocking Textiles
Holt, B.; Oswalt, K.; England, A.; Murphy, R.; Owens, I.; Finney, M.; Wong, N.; Adhikari, S.; McCann, J.; Beckmann, J. F.
10.1101/2023.04.21.537869 — bioengineering — Posted on 2023-04-24
986 Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution
Duffet, L.; Williams, E. T.; Gresch, A.; Chen, S.; Bhat, M. A.; Benke, D.; Hartrampf, N.; Patriarchi, T.
10.1101/2023.02.14.528498 — biochemistry — Posted on 2023-04-24
987 Cortical cellular encoding of thermotactile integration
Schnepel, P.; Paricio-Montesinos, R.; Ezquerra-Romano, I.; Haggard, P.; Poulet, J. F. A.
10.1101/2023.04.23.537915 — neuroscience — Posted on 2023-04-24
989 Structural genomic variation and migratory behavior in wild songbirds
Delmore, K.; Van Doren, B. M.; Ullrich, K.; Curk, T.; van der Jeugd, H. P.; Liedvogel, M.
10.1101/2023.04.24.538030 — evolutionary biology — Posted on 2023-04-24
993 Cortical Plasticity is associated with Blood-Brain-Barrier Modulation
Swissa, E.; Monsonego, U.; Yang, L. T.; Schori, L.; Kamintsky, L.; Mirloo, S.; Burger, I.; Uzzan, S.; Patel, R.; Sudmant, P. H.; Prager, O.; Kaufer, D.; Friedman, A.
10.1101/2023.04.23.537964 — neuroscience — Posted on 2023-04-24
995 Sulfate reducing bacteria are active and co-occur with diatoms during a spring phytoplankton bloom
Siebers, R.; Schultz, D.; Farza, S. M.; Brauer, A.; Zuehlke, D.; Hoff, K.; Muecke, P. A.; Francis, T. B.; Bernhardt, J.; Teeling, H.; Becher, D.; Riedel, K.; Urich, T.; Bengtsson, M. M.
10.1101/2022.05.31.494182 — ecology — Posted on 2023-04-24
996 Oxygen concentration modulates colibactin production
Bossuet, N.; Guyonnet, C.; Chagneau, C.; Tang-Fichaux, M.; Penary, M.; Loubet, D.; Branchu, P.; Oswald, E.; Nougayrede, J.-P.
10.1101/2022.06.20.496773 — microbiology — Posted on 2023-04-24
1000 Evidence for a role of human blood-borne factors in mediating age-associated changes in molecular circadian rhythms
Schwarz, J. E.; Mrcela, A.; Lahens, N. F.; Li, Y.; Hsu, C.; Grant, G.; Skarke, C.; Zhang, S. L.; Sehgal, A.
10.1101/2023.04.19.537477 — molecular biology — Posted on 2023-04-24
1002 Preimplantation Embryos Amplify Sperm-Derived miRNA Levels to Mediate Transgenerational Epigenetic Inheritance
Champroux, A.; Yang, T.; Dickson, D. A.; Meng, A.; Harrington, A.; Liaw, L.; Marzi, M.; Nicassio, F.; Schlaeger, T.; Feig, L.
10.1101/2023.04.21.537854 — genetics — Posted on 2023-04-24
1005 Metagenomics uncovers dietary adaptations for chitin digestion in the gut microbiota of convergent myrmecophagous mammals
Teullet, S.; Tilak, M.-K.; Magdeleine, A.; Schaub, R.; Weyer, N. M.; Panaino, W.; Fuller, A.; Loughry, W. J.; Avenant, N. L.; de Thoisy, B.; Borrel, G.; Delsuc, F.
10.1101/2023.04.21.537829 — evolutionary biology — Posted on 2023-04-24
1006 GAN-MAT: Generative Adversarial Network-based Microstructural Profile Covariance Analysis Toolbox
Park, Y. J.; Lee, M. J.; Yoo, S.; Kim, C. Y.; Namgung, J. Y.; Park, Y.; Park, H.; Lee, E.-C.; Yun, Y. D.; Paquola, C.; Bernhardt, B.; Park, B.-y.
10.1101/2023.04.20.537642 — neuroscience — Posted on 2023-04-24
1008 ESCRT disruption provides evidence against signaling functions for synaptic exosomes
Dresselhaus, E. C.; Harris, K. P.; Koles, K.; Pescosolido, M. F.; Ermanoska, B.; Rozencwaig, M.; Soslowsky, R. C.; Stewart, B. A.; Rodal, A. A.
10.1101/2023.04.22.537920 — cell biology — Posted on 2023-04-24
1009 Iterative immunostaining combined with expansion microscopy and image processing reveals nanoscopic network organization of nuclear lamina
Mantyla, E.; Montonen, T.; Azzari, L.; Mattola, S.; Hannula, M.; Vihinen-Ranta, M.; Hyttinen, J.; Vippola, M.; Foi, A.; Nymark, S.; Ihalainen, T. O.
10.1101/2022.09.27.509734 — molecular biology — Posted on 2023-04-24
1011 Treatment with sodium butyrate induces autophagy resulting in therapeutic benefits for spinocerebellar ataxia-3
Watchon, M.; Robinson, K. J.; Luu, L.; Yuan, K.; Plenderleith, S. K.; Cheng, F.; Don, E. K.; Nicholson, G.; Lee, A.; Laird, A. S.
10.1101/2021.04.30.442119 — neuroscience — Posted on 2023-04-24
1012 The WW domain of IQGAP1 binds directly to the p110α catalytic subunit of PI 3-kinase
Bardwell, A. J.; Paul, M.; Yoneda, K. C.; Andrade-Ludena, M. D.; Nguyen, O. T.; Fruman, D. A.; Bardwell, L.
10.1101/2022.09.24.509339 — biochemistry — Posted on 2023-04-24
1016 Phylogeny, morphology, virulence, ecology, and host range of Ordospora pajunii (Ordosporidae),a microsporidian symbiont of Daphnia spp.
Dziuba, M. K.; McIntire, K. M.; Seto, K.; Davenport, E. S.; Rogalski, M. A.; Gowler, C. D.; Baird, E.; Vaandrager, M.; Huerta, C.; Jaye, R.; Corcoran, F. E.; Withrow, A.; Ahrendt, S.; Salamov, A.; Nolan, M.; Tejomurthula, S.; Barry, K.; Grigoriev, I.; James, T.; Duffy, M. A.
10.1101/2023.04.21.537887 — ecology — Posted on 2023-04-24
1018 Abnormal intrinsic neural timescale and reduced grey matter volume in Parkinson's disease
Wei, Y.; Zhang, C.; Peng, Y.; Chen, C.; Han, S.; Wang, W.; Zhang, Y.; Lu, H.; Cheng, J.
10.1101/2022.09.17.508074 — neuroscience — Posted on 2023-04-24
1020 Effects of sensorineural hearing loss on formant-frequency discrimination: Measurements and models
Carney, L. H.; Cameron, D. A.; Kinast, K. B.; Feld, C. E.; Schwarz, D. M.; Leong, U.-C.; McDonough, J. M.
10.1101/2022.10.26.513920 — neuroscience — Posted on 2023-04-24
1021 Mena and VASP are required for vascular smooth muscle relaxation
Ulrich, L.; Gliem, C.; Groneberg, D.; Froemel, T.; Schuh, K.; Fleming, I.; Benz, P. M.
10.1101/2023.04.21.537622 — physiology — Posted on 2023-04-24
1030 Learning from the expert: studying Salicornia to understand salinity tolerance
Salazar, O. R.; Chen, K.; Melino, V. J.; Reddy, M. P.; Hribova, E.; Cizkova, J.; Berankova, D.; Aranda, M.; Jaremko, L.; Jaremko, M.; Fedoroff, N. V.; Tester, M.; Schmöckel, S. M.
10.1101/2023.04.21.537482 — plant biology — Posted on 2023-04-23
1031 Maize COI1 quadruple-knockout mutants exhibit elevated DELLA protein accumulation, stunted growth, and reduced photosynthetic efficiency
Feiz, L.; Shyu, C.; Wu, S.; Ahern, K. R.; Gull, I.; Artymowicz, C. J.; Pineros, M. A.; Fei, Z.; Brutnell, T. P.; Jander, G.
10.1101/2023.04.21.537853 — plant biology — Posted on 2023-04-23
1033 Label-free Identification of Protein Aggregates Using Deep Learning
Ibrahim, K. A.; Grussmayer, K. S.; Riguet, N.; Feletti, L.; Lashuel, H.; Radenovic, A.
10.1101/2023.04.21.537833 — bioengineering — Posted on 2023-04-23
1034 Codon affinity in mitochondrial DNA shapes evolutionary and somatic fitness
Lareau, C. A.; Yin, Y.; Gutierrez, J. C.; Dhindsa, R. S.; Gribling-Burrer, A.-S.; Hsieh, Y.-H.; Nitsch, L.; Buquicchio, F. A.; Abay, T.; Zielinski, S.; Stickels, R. R.; Ulirsch, J. C.; Yan, P.; Wang, F.; Miao, Z.; Sandor, K.; Daniel, B.; Liu, V.; Wang, Q.; Hu, F.; Smith, K. R.; Deevi, S. V. V.; Maschmeyer, P.; Petrovski, S.; Smyth, R. P.; Greenleaf, W. J.; Kundaje, A.; Munschauer, M.; Ludwig, L. S.; Satpathy, A. T.
10.1101/2023.04.23.537997 — genetics — Posted on 2023-04-23
1035 A comparative analysis of the antiviral response in two bat species reveals conserved and divergent innate immune pathways
Schneor, L.; Kaltenbach, S.; Fridman, S.; Nissan, Y.; Shuler, G.; Fraimovitch, E.; Weinberg, M.; Kolodziejczyk, A. A.; Donati, G.; Teeling, E. C.; Yovel, Y.; Hagai, T.
10.1101/2023.04.23.537989 — evolutionary biology — Posted on 2023-04-23
1036 A Key Piece of the Puzzle: The central tetramer of the Saccharomyces cerevisiae septin protofilament and Its Implications for Self-Assembly
Marques da Silva, R.; dos Reis Saladino, G. C.; Leonardo, D. A.; D'Muniz Pereira, H.; Sculaccio, S. A.; Ulian de Araujo, A. P.; Garratt, R. C.
10.1101/2023.04.22.537027 — molecular biology — Posted on 2023-04-23
1040 Neuronal Population Encoding of Identity in Primate Prefrontal Cortex
Sharma, K. K.; Diltz, M.; Lincoln, T.; Albuquerque, E. R.; Romanski, L. M.
10.1101/2022.06.26.497629 — neuroscience — Posted on 2023-04-23
1041 Gibberellin transport affects (lateral) root growth through HY5 during Far-Red light enrichment.
van Gelderen, K. v.; van der Velde, K.; Kang, C.-K.; Hollander, J.; Petropoulos, O.; Akyuz, T.; Pierik, R.
10.1101/2023.04.21.537844 — plant biology — Posted on 2023-04-23
1043 CNC Knitting Micro-Resolution Mosquito Bite Blocking Textiles
Beckmann, J. F.; Holt, B.; Oswalt, K.; England, A.; Murphy, R.; Owens, I.; Finney, M.; Wong, N.; Adhikari, S.; McCann, J.
10.1101/2023.04.21.537869 — bioengineering — Posted on 2023-04-23
1045 Blood and cerebellar abundance of ATXN3 splice variants in spinocerebellar ataxia type 3/Machado-Joseph disease
Raposo, M.; Hubener-Schmid, J.; Tagett, R.; Ferreira, A. F.; Vieira Melo, A. R.; Vasconcelos, J.; Pires, P.; Kay, T.; Garcia-Moreno, H.; Giunti, P.; Santana, M. M.; Pereira de Almeida, L.; Infante, J.; van de Warrenburg, B. P.; de Vries, J. J.; Faber, J.; Klockgether, T.; Casadei, N.; Admard, J.; Schols, L.; Riess, O.; European Spinocerebellar ataxia type 3/Machado-Joseph disease Initiative (ESMI) study group, ; Costa, M. d. C.; Lima, M.
10.1101/2023.04.22.537936 — genetics — Posted on 2023-04-23
1046 Mouse Homolog of Human IRF8G388S Mutation Provides Novel Insight into Osteoclastogenesis and Tooth Root Resorption
Das, A.; Yesupatham, S. K.; Allison, D.; Tanwar, H.; Gnanasekaran, J.; Kear, B.; Wang, X.; Wang, S.; Zachariadou, C.; Abbasi, Y.; Chung, M.-K.; Ozato, K.; Liu, C.; Foster, B. L.; Math, V. T.
10.1101/2023.04.23.537931 — genetics — Posted on 2023-04-23
1047 Genomic and Radiocarbon Insights into the Mystery of Mouse Mummies on the Summits of >6000 m Andean Volcanoes
Storz, J. F.; Liphardt, S.; Quiroga-Carmona, M.; Bautista, N. M.; Opazo, J. C.; Wheeler, T. B.; D'Elia, G.; Good, J. M.
10.1101/2023.04.22.537927 — evolutionary biology — Posted on 2023-04-23
1049 Massive expansion of the pig gut virome based on global metagenomic mining
Mi, J.; Jing, X.; Ma, C.; Yang, Y.; Li, Y.; Zhang, Y.; Long, R.; Zheng, H.
10.1101/2023.04.22.537307 — microbiology — Posted on 2023-04-23
1051 Long-term labeling and imaging of synaptically-connected neuronal networks in vivo using nontoxic, double-deletion-mutant rabies viruses
Jin, L.; Sullivan, H. A.; Zhu, M.; Lavin, T. K.; Matsuyama, M.; Fu, X.; Lea, N. E.; Xu, R.; Hou, Y.; Rutigliani, L.; Pruner, M. T.; Babcock, K. R.; Ip, J. P. K.; Hu, M.; Daigle, T. L.; Zeng, H.; Sur, M.; Feng, G.; Wickersham, I. R.
10.1101/2021.12.04.471186 — neuroscience — Posted on 2023-04-23
1053 CDK7 is a Novel Therapeutic Vulnerability in Fibrolamellar Carcinoma
Nukaya, M.; Cafferty, C.; Zahed, K.; Yun, I.; Al-Adra, D. P.; Kazim, N. A.; Farghli, A. R.; Chan, M.; Kratz, J. D.; Berres, M. E.; Yen, A.; Gujral, T.; Sethupathy, P.; Bradfield, C. A.; Ronnekleiv-Kelly, S. M.
10.1101/2023.04.22.537934 — cancer biology — Posted on 2023-04-23
1055 Active Transcription and Epigenetic Reactions Synergistically RegulateMeso-Scale Genomic Organization
Kant, A.; Guo, Z.; Vinayak, V.; Neguembor, M. V.; Li, W. S.; Agrawal, V.; Pujadas, E.; Almassalha, L. M.; Backman, V.; Lakadamyali, M.; Cosma, M. P.; Shenoy, V.
10.1101/2023.04.21.537822 — biophysics — Posted on 2023-04-23
1060 The Cyclimids: Degron-inspired cereblon binders for targeted protein degradation
Ichikawa, S.; Payne, N. C.; Xu, W.; Chang, C.-F.; Vallavoju, N.; Frome, S.; Flaxman, H. A.; Mazitschek, R.; Woo, C. M.
10.1101/2023.04.22.537935 — biochemistry — Posted on 2023-04-23
1061 Global determinants of insect genetic diversity
French, C. M.; Bertola, L. D.; Carnaval, A. C.; Economo, E. P.; Kass, J. M.; Lohman, D. J.; Marske, K. A.; Meier, R.; Overcast, I.; Rominger, A. J.; Staniczenko, P.; Hickerson, M. J.
10.1101/2022.02.09.479762 — evolutionary biology — Posted on 2023-04-23
1062 Derivation of trophoblast stem cells unveils unrestrained potential of mouse ESCs and epiblast
Jana, D.; Sailasree, P.; Singh, P.; Srivastava, M.; Vishnu, V. V.; Kale, H. T.; Lakshmi, B. J.; Srinivas, G.; Sowpati, D. T.; Shekar, P. C.
10.1101/2023.04.19.537518 — developmental biology — Posted on 2023-04-23
1064 Longitudinal Survey of Astrovirus infection in different bat species in Zimbabwe: Evidence of high genetic Astrovirus diversity
Chidoti, V.; De Nys, H.; Abdi, M.; Mashura, G.; Pinarello, V.; Chiweshe, N.; Matope, G.; Guerrini, L.; Pfulenyi, D.; Cappelle, J.; Mwandiringana, E.; Misse, D.; Elizabeth, G.; Bourgarel, M.; Liegeois, F.
10.1101/2023.04.14.536987 — molecular biology — Posted on 2023-04-23
1066 Quantifying Evoked Responses through Information-Theoretical Measures
Fuhrer, J.; Glette, K.; Llorens, A.; Endestad, T.; Solbakk, A.-K.; Blenkmann, A.
10.1101/2022.11.11.516096 — neuroscience — Posted on 2023-04-23
1067 A DRG genetic toolkit reveals molecular, morphological, and functional diversity of somatosensory neuron subtypes
Qi, L.; Iskols, M.; Shi, D.; Reddy, P.; Walker, C.; Lezgiyeva, K.; Voisin, T.; Pawlak, M.; Kuchroo, V. K.; Chiu, I.; Ginty, D. D.; Sharma, N.
10.1101/2023.04.22.537932 — neuroscience — Posted on 2023-04-23
1069 Long-term labeling and imaging of synaptically-connected neuronal networks in vivo using nontoxic, double-deletion-mutant rabies viruses
Jin, L.; Sullivan, H. A.; Zhu, M.; Lavin, T. K.; Matsuyama, M.; Fu, X.; Lea, N. E.; Xu, R.; Hou, Y.; Rutigliani, L.; Pruner, M. T.; Babcock, K. R.; Ip, J. P. K.; Hu, M.; Daigle, T. L.; Zeng, H.; Sur, M.; Feng, G.; Wickersham, I. R.
10.1101/2021.12.04.471186 — neuroscience — Posted on 2023-04-22
1072 Role of GD2 and its biosynthetic enzyme GD3 synthase in prostate cancer tumorigenesis
Bhat, A. M.; Mohapatra, B. C.; Luan, H.; Mushtaq, I.; Chakraborty, S.; Dutta, S.; Stock, M. D.; Meza, J. L.; Lele, S. M.; Lin, M.-F.; Cook, L. M.; Corey, E.; Morrissey, C.; Coulter, D. W.; Rowley, J.; Datta, K.; Band, V.; Band, H.
10.1101/2023.03.18.533299 — cancer biology — Posted on 2023-04-22
1073 in vivo quantitative FRET small animal imaging: intensity versus lifetime-based FRET
Smith, J. T.; Sinsuebphon, N.; Rudkouskaya, A.; Michalet, X.; Intes, X.; Barroso, M.
10.1101/2023.01.24.525411 — biophysics — Posted on 2023-04-22
1075 OME-Zarr: a cloud-optimized bioimaging file format with international community support
Moore, J.; Basurto-Lozada, D.; Besson, S.; Bogovic, J.; Bragantini, J.; Brown, E. M.; Burel, J.-M.; Casas Moreno, X.; de Medeiros, G.; Diel, E. E.; Gault, D.; Ghosh, S. S.; Gold, I.; Halchenko, Y. O.; Hartley, M.; Horsfall, D.; Keller, M. S.; Kittisopikul, M.; Kovacs, G.; Küpcü Yoldas, A.; Kyoda, K.; le Tournoulx de la Villegeorges, A.; Li, T.; Liberali, P.; Lindner, D.; Linkert, M.; Lüthi, J.; Maitin-Shepard, J.; Manz, T.; Marconato, L.; McCormick, M.; Lange, M.; Mohamed, K.; Moore, W.; Norlin, N.; Özdemir, B.; Palla, G.; Pape, C.; Pelkmans, L.; Pietzsch, T.; Preibisch, S.; Prete, M.; Rze
10.1101/2023.02.17.528834 — bioinformatics — Posted on 2023-04-22
1079 Isoform-specific translational control is evolutionarily conserved in primates
Draper, J. M.; Philipp, J.; Neeb, Z. T.; Thomas, R.; Katzman, S.; Salama, S.; Haussler, D.; Sanford, J.
10.1101/2023.04.21.537863 — molecular biology — Posted on 2023-04-22
1080 Progesterone is an Inducement of Heritable Pulmonary Arterial Hypertension with BMPR2 Mutation
Hu, W.; Zhang, S.-J.; Ding, Y.-J.; Fang, J.; Zhou, L.; Xie, S.; Ge, X.; Fu, L.; Li, Q.-Y.; Qu, J.; Li, S.; Liu, D.
10.1101/2023.04.21.537897 — molecular biology — Posted on 2023-04-22
1081 WNT2B Deficiency Causes Increased Susceptibility to Colitis in Mice and Impairs Intestinal Epithelial Development in Humans
O'Connell, A. E.; Raveenthiraraj, S.; Adegboye, C.; Qi, W.; Khetani, R. S.; Singh, A.; Sundaram, N.; Emeonye, C.; Lin, J.; Goldsmith, J. D.; Thiagarajah, J. R.; Carlone, D.; Turner, J. R.; Agrawal, P. B.; Helmrath, M.; Breault, D. T.
10.1101/2023.04.21.537894 — molecular biology — Posted on 2023-04-22
1084 A TNF-IL-1 circuit controls Yersinia within intestinal granulomas
Matsuda, R.; Sorobetea, D.; Zhang, J.; Peterson, S. T.; Grayczyk, J. P.; Herrmann, B.; Yost, W.; O'Neill, R.; Bohrer, A. C.; Lanza, M.; Assenmacher, C.-A.; Mayer-Barber, K. D.; Shin, S.; Brodsky, I. E.
10.1101/2023.04.21.537749 — immunology — Posted on 2023-04-22
1085 Identification of a new pharyngeal mucosal lymphoid organ in zebrafish and other teleosts: tonsils in fish?
RESSEGUIER, J.; NGUYEN-CHI, M.-E.; WOHLMANN, J.; RIGAUDEAU, D.; SALINAS, I.; OEHLERS, S. H.; WIEGERTJES, G. F.; JOHANSEN, F.-E.; QIAO, S.-W.; KOPPANG, E. O.; VERRIER, B.; BOUDINOT, P.; GRIFFITHS, G.
10.1101/2023.03.13.532382 — immunology — Posted on 2023-04-22
1087 A FLOWERING LOCUS T ortholog is associated with photoperiod-insensitive flowering in hemp (Cannabis sativa L.)
Dowling, C. A.; Shi, J.; Toth, J. A.; Quade, M. A.; Smart, L. B.; McCabe, P. F.; Melzer, R.; Schilling, S.
10.1101/2023.04.21.537862 — plant biology — Posted on 2023-04-22
1090 Structure of a dimeric ABC transporter
Bickers, S. C.; Benlekbir, S.; Rubinstein, J. L.; Kanelis, V.
10.1101/2023.04.21.537812 — biochemistry — Posted on 2023-04-22
1092 Development of genomic resources for cattails (Typha), a globally important macrophyte genus
Aleman, J. A.; Dorken, M. E.; Shafer, A.; Patel, T.; Volkova, P. A.; Freeland, J. R.
10.1101/2023.04.21.537876 — molecular biology — Posted on 2023-04-22
1093 Early-life obesogenic environment integrates immunometabolic and epigenetic signatures governing neuroinflammation
Ontiveros-Angel, P.; Vega-Torres, J. D.; Simon, T. B.; Williams, V.; Inostroza-Nives, Y.; Alvarado-Crespo, N.; Vega Gonzalez, Y.; Pompolius, M.; Katzka, W.; Lou, J.; Sharafeddin, F.; De La Pena, I.; Dong, T.; Gupta, A.; Viet, C. T.; Febo, M.; Obenaus, A.; Figueroa, J. D.
10.1101/2023.04.21.537874 — neuroscience — Posted on 2023-04-22
1099 Spatiotemporal transcriptome atlas of human embryos after gastrulation
Pan, J.; Li, Y.; Lin, Z.; Lan, Q.; Chen, H.; Zhai, M.; Sui, S.; Zhang, G.; Cheng, Y.; Tang, Y.; Wang, Q.; Zhang, Y.; Ma, F.; Xu, Y.; Mao, Y.; Chen, Q.; Guan, Y.; Meng, N.; Lu, H.; Li, X.; Zheng, T.; Yao, X.; Qin, Q.; Jiang, B.; Ren, Y.; Luo, M.; Nacuo, J.; Jin, X.; Sheng, J.; Xu, C.; Liu, X.; Wu, Y.; Xu, C.; Zhao, L.; Yang, H.; Gao, Y.; Ding, G.; Xu, X.; Huang, H.
10.1101/2023.04.22.537909 — developmental biology — Posted on 2023-04-22
1100 Association of inflammation and tissue damage inducedbiological processes in masseter muscle with the resolution of chronic myalgia
Lindquist, K. A.; Shein, S. A.; Hovhannisyan, A. H.; Mecklenburg, J.; Zou, Y.; Lai, Z.; Tumanov, A. V.; Akopian, A. N.
10.1101/2023.04.21.537828 — neuroscience — Posted on 2023-04-22
1102 Transcriptional dissection of symptomatic profiles across the brain of men and women with depression
mansouri, s.; Pessoni, A. M.; Rivera, A. M.; Tamminga, C. A.; Parise, E.; Turecki, G.; Nestler, E. J.; Chen, T.-H.; Labonte, B.
10.1101/2023.04.21.537733 — neuroscience — Posted on 2023-04-22
1103 Whole-genome sequencing across 449 samples spanning 47 ethnolinguistic groups provides insights into genetic diversity in Nigeria
Joshi, E.; Biddanda, A.; Popoola, J.; Yakubu, A.; Osakwe, O.; Attipoe, D.; 54gene Team, ; NCD-GHS Consortium, ; Dogbo, E.; Salako, B.; Nash, O.; Salako, O.; Oyedele, O.; Eze-Echesi, G.; Fatumo, S.; Ene-Obong, A.; O'Dushlaine, C.
10.1101/2022.12.09.519178 — genomics — Posted on 2023-04-22
1105 Renal Cl-/H+ antiporter ClC-5 regulates collagen production and release in Dent Disease models
Duran, M.; Ariceta, G.; Semidey, M. E.; Castells-Esteve, C.; Lu, B.; Meseguer, A.; Cantero, G.
10.1101/2023.04.21.537823 — cell biology — Posted on 2023-04-22
1106 Mitochondrial genome editing: a possible interplay of atherosclerosis-associated mutation m.15059G>A with defective mitophagy
Khotina, V. A.; Kalmykov, V. A.; Zhuravlev, A. D.; Sinyov, V. V.; Sobenin, I.; Orekhov, A. N.; Sukhorukov, V. N.
10.1101/2023.04.21.537899 — cell biology — Posted on 2023-04-22
1107 A metabolically controlled contact site between lipid droplets and vacuoles
Diep, D. T. V.; Collado, J.; Hugenroth, M.; Wälte, M.; Schmidt, O.; Fernandez-Busnadiego, R.; Bohnert, M.
10.1101/2023.04.21.537652 — cell biology — Posted on 2023-04-22
1108 CHAF1A promotes the translesion DNA synthesis pathway in response to DNA replication stress
Wen, B.; Zheng, H.-X.; Deng, D.-X.; Zhang, Z.-D.; Heng, J.-H.; Liao, L.-D.; Xu, L.-Y.; Li, E.-M.
10.1101/2023.04.21.537900 — cell biology — Posted on 2023-04-22
1109 Tbx5 maintains atrial identity by regulating an atrial enhancer network
Sweat, M. E.; Cao, Y.; Zhang, X.; Burnicka-Turek, O.; Perez-Cervantes, C.; Akerberg, B. N.; Ma, Q.; Wakimoto, H.; Gorham, J. M.; Song, M. K.; Trembley, M. A.; Wang, P.; Lu, F.; Gianeselli, M.; Prondzynski, M.; Bortolin, R. H.; Seidman, J. G.; Seidman, C.; Moskowitz, I. P.; Pu, W. T.
10.1101/2023.04.21.537535 — cell biology — Posted on 2023-04-22
1111 Towards a Foundation Model of the Mouse Visual Cortex
Wang, E. Y.; Fahey, P. G.; Ponder, K.; Ding, Z.; Chang, A.; Muhammad, T.; Patel, S.; Ding, Z.; Tran, D. T.; Fu, J.; Papadopoulos, S.; Franke, K.; Ecker, A. S.; Reimer, J.; Pitkow, X.; Sinz, F. H.; Tolias, A. S.
10.1101/2023.03.21.533548 — neuroscience — Posted on 2023-04-22
1113 The genome of Talinum fruticosum
Brilhaus, D.; Denton, A. K.; Maleckova, E.; Reichel-Deland, V.; Weber, A. P. M.
10.1101/2023.04.20.537669 — plant biology — Posted on 2023-04-22
1114 A Human Breast Cell Atlas Mapping the Homeostatic Cellular Shifts in the Adult Breast
Reed, A. D.; Pensa, S.; Steif, A.; Stenning, J.; Kunz, D.; He, P.; Twigger, A.-J.; Kania, K.; Barrow, R.; Goulding, I.; Gomm, J.; Jones, L.; Marioni, J.; Khaled, W. T.
10.1101/2023.04.21.537845 — cancer biology — Posted on 2023-04-22
1118 Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts
Zhou, W.; Karan, K. R.; Gu, W.; Klein, H.-U.; Sturm, G.; De Jager, P. L.; Bennett, D. A.; Hirano, M.; Picard, M.; Mills, R. E.
10.1101/2023.02.03.527065 — genomics — Posted on 2023-04-21
1119 Parallel shifts in flight-height associated with altitude across incipient Heliconius species
Rivas-Sanchez, D. F.; Gantiva-Q, C. H.; Pardo-Diaz, C.; Salazar, C.; Montgomery, S. H.; Merrill, R. M.
10.1101/2023.04.12.536626 — evolutionary biology — Posted on 2023-04-21
1120 Diverse and Abundant Viruses Exploit Conjugative Plasmids
Quinones-Olvera, N.; Owen, S. V.; McCully, L. M.; Marin, M. G.; Rand, E. A.; Fan, A. C.; Dosumu, O. J. M.; Paul, K.; Castano, C. E. S.; Petherbridge, R.; Paull, J. S.; Baym, M.
10.1101/2023.03.19.532758 — microbiology — Posted on 2023-04-21
1121 A two-hit epistasis model prevents core genome disharmony in recombining bacteria
Taylor, A. J.; Yahara, K.; Pascoe, B.; Mageiros, L.; Mourkas, E.; Calland, J. K.; Puranen, S.; Hitchings, M. D.; Jolley, K. A.; Kobras, C. M.; Bayliss, S. C.; Williams, N. J.; van Vliet, A. H.; Parkhill, J.; Maiden, M. C.; Corander, J.; Hurst, L. D.; Falush, D.; Keim, P.; Didelot, X.; Kelly, D. J.; Sheppard, S. K.
10.1101/2021.03.15.435406 — microbiology — Posted on 2023-04-21
1122 Venom protection by broadly neutralizing antibody from a snakebite subject
Glanville, J.; Andrade, J. C.; Bellin, M.; Kim, S.; Pletnev, S.; Tsao, D.; Verardi, R.; Bedi, R.; Liao, S.; Newland, R.; Bayless, N. L.; Youssef, S.; Tully, E.; Zhang, B.; Bylund, T.; Kim, S.; Liu, T.; Kwong, P. D.
10.1101/2022.09.26.507364 — immunology — Posted on 2023-04-21
1124 NAD homeostasis maintained by NMNAT2 supports vesicular glycolysis and fuels fast axonal transport in distal axons of cortical glutamatergic neurons in mice
Yang, S.; Niou, Z.-X.; Enriquez, A.; LaMar, J.; Huang, J.-Y.; Ling, K.; Jafar-Nejad, P.; Gilley, J.; Coleman, M. P.; Tennessen, J.; Rangaraju, V.; Lu, H.-C.
10.1101/2022.02.06.479307 — neuroscience — Posted on 2023-04-21
1130 Genetic contributions of noncognitive skills to academic development
Malanchini, M.; Allegrini, A. G.; Nivard, M. G.; Biroli, P.; Rimfeld, K.; Cheesman, R.; von Stumm, S.; Demange, P. A.; van Bergen, E.; Grotzinger, A. D.; Raffington, L.; de la Fuente, J.; Pingault, J.-B.; Harden, K. P.; Tucker-Drob, E. M.; Plomin, R.
10.1101/2023.04.03.535380 — genetics — Posted on 2023-04-21
1132 Spatial transcriptome profiling uncovers metabolic regulation of left-right patterning
Yagi, H.; Cui, C.; Saydmohammed, M.; Gabriel, G.; Baker, C.; Devine, W.; Wu, Y.; Lin, J.-h.; Malek, M.; Bais, A.; Murray, S.; Aronow, B. J.; Tsang, M. J.; Kostka, D.; Lo, C. W.
10.1101/2023.04.21.537827 — developmental biology — Posted on 2023-04-21
1133 Intestinal transit amplifying cells require METTL3 for growth factor signaling, KRAS expression, and cell survival
Danan, C. H.; Naughton, K. E.; Hayer, K. E.; Vellapan, S.; McMillan, E. A.; Zhou, Y.; Matsuda, R.; Nettleford, S. K.; Katada, K.; Parham, L. R.; Ma, X.; Chowdhury, A.; Wilkins, B. J.; Shah, P.; Weitzman, M. D.; Hamilton, K. E.
10.1101/2023.04.06.535853 — cell biology — Posted on 2023-04-21
1134 Human olfactory neuronal cells through nasal biopsy: molecular characterization and utility in brain science
Yang, K.; Ishizuka, K.; Lane, A. P.; Narita, Z.; Lema, Y. Y.; Tomoda, T.; Kamiya, A.; Ma, M.; Geman, D.; Younes, L.; Sawa, A.
10.1101/2022.09.23.509290 — molecular biology — Posted on 2023-04-21
1135 MAVS signaling is required for clearance of chikungunya heart infection and prevention of chronic inflammation in vascular tissue
Noval, M. G.; Spector, S. N.; Bartnicki, E.; Izzo, F.; Narula, N.; Yeung, S. T.; Damani-Yokota, P.; Dewan, M. Z.; Mezzano, V.; Rodriguez-Rodriguez, B. A.; Loomis, C.; Khanna, K. M.; Stapleford, K. A.
10.1101/2022.05.27.493768 — microbiology — Posted on 2023-04-21
1139 Sub-second striatal dopamine dynamics assessed by simultaneous fast-scan cyclic voltammetry and fluorescence biosensor
Salinas, A. G.; Lee, J. O.; Augustin, S. M.; Zhang, S.; Patriarchi, T.; Tian, L.; Morales, M.; Mateo, Y.; Lovinger, D. M.
10.1101/2022.01.09.475513 — neuroscience — Posted on 2023-04-21
1140 Targeted V1 comodulation supports task-adaptive sensory decisions
Haimerl, C.; Ruff, D. A.; Cohen, M. R.; Savin, C.; Simoncelli, E. P.
10.1101/2021.02.23.432351 — neuroscience — Posted on 2023-04-21
1143 Exploring the Interdependence of TKS4 and CD2AP: Implications for EMT Process and Early Detection in Colon Cancer
Kurilla, A.; Laszlo, L.; Takacs, T.; Tilajka, A.; Lukacs, L.; Novak, J.; Pancsa, R.; Buday, L.; Vas, V.
10.1101/2023.01.13.523903 — cancer biology — Posted on 2023-04-21
1149 Cardiac-Gated Spectroscopic Photoacoustic Imaging for Ablation-Induced Necrotic Lesion Visualization: In Vivo Demonstration in a Beating Heart
Gao, S.; Ashikaga, H.; Suzuki, M.; Mansi, T.; Kim, Y.-H.; Ghesu, F.-C.; Kang, J.; Boctor, E. M.; Halperin, H. R.; Zhang, H. K.
10.1101/2022.05.23.492682 — bioengineering — Posted on 2023-04-21
1150 Intracellular biotransformation and disposal mechanisms of magnetosomes in macrophages and cancer cells
Gandarias, L.; G. Gubieda, A.; Gorni, G.; Mathon, O.; Olivi, L.; Abad-Diaz-de-Cerio, A.; Fdez-Gubieda, M. L.; Muela, A.; Garcia-Prieto, A.
10.1101/2023.03.15.532722 — biochemistry — Posted on 2023-04-21
1153 Early prediction of declining health in small ruminants with accelerometers and machine learning
Montout, A. X.; Bhamber, R. S.; Lange, D. S.; Ndlovu, D. Z.; Morgan, E. R.; Ioannou, C. C.; Terrill, T. H.; Van Wyk, J. A.; Burghardt, T.; Dowsey, A. W.
10.1101/2020.08.03.234203 — animal behavior and cognition — Posted on 2023-04-21
1155 LDO proteins and Vac8 form a vacuole-lipid droplet contact site required for lipophagy in response to starvation
Alvarez-Guerra, I.; Block, E.; Broeskamp, F.; Gabrijelcic, S.; de Ory, A.; Habernig, L.; Andreasson, C.; Levine, T.; Höög, J. L.; Büttner, S.
10.1101/2023.04.21.537797 — cell biology — Posted on 2023-04-21
1156 Genomic Changes During the Evolution of the Coxiella Genus Along the Parasitism-Mutualism Continuum.
Santos-Garcia, D.; Morel, O.; Henri, H.; El Filali, A.; Buysse, M.; Noël, V.; McCoy, K. D.; Gottlieb, Y.; Klasson, L.; Zenner, L.; Duron, O.; Vavre, F.
10.1101/2022.10.26.513839 — microbiology — Posted on 2023-04-21
1158 Tuning the potency and therapeutic window of ImmTAC molecules by affinity modulation
Robertson, I. B.; Mulvaney, R. M.; Dieckmann, N.; Vantellini, A.; Canestraro, M.; Amicarella, F.; O'Dwyer, R.; Cole, D. K.; Harper, S.; Dushek, O.; Kirk, P.
10.1101/2022.11.03.511676 — immunology — Posted on 2023-04-21
1162 Hematopoietic Transfer of the Anti-Cancer and Lifespan-Extending Capabilities of A Genetically Engineered Blood System
Wang, J.-P.; Hung, C.-H.; Liou, Y.-H.; Liu, C.-C.; Yeh, K.-H.; Wang, K.-Y.; Lai, Z.-S.; Hsu, T.-C.; Lee, T.-L.; Shyu, Y.-C.; Hsiao, P.-W.; Chen, L.-Y.; Chuang, T.-J.; Yu, C.-H. A.; Liao, N.-S.; Shen, C.-K. J.
10.1101/2023.04.21.537849 — cancer biology — Posted on 2023-04-21
1163 Correcting 4sU induced quantification bias in nucleotide conversion RNA-seq data
Berg, K.; Lodha, M.; Garcia, Y. C.; Hennig, T.; Wolf, E.; Prusty, B.; Erhard, F.
10.1101/2023.04.21.537786 — bioinformatics — Posted on 2023-04-21
1166 Genetic tools for the study of the mangrove killifish, Kryptolebias marmoratus, an emerging vertebrate model for phenotypic plasticity
Li, C.-Y.; Boldt, H.; Parent, E.; Ficklin, J.; James, A.; Anlage, T. J.; Boyer, L. M.; Pierce, B. R.; Siegfried, K.; Harris, M. P.; Haag, E. S.
10.1101/2023.04.21.537589 — developmental biology — Posted on 2023-04-21
1167 Myocardial IGF2R is a critical mediator of inflammation and fibrosis after ischemia-reperfusion injury
Wu, Z.; Huang, W.; He, X.; Dutta, S.; Paul, C.; Fan, G.-C.; Kanisicak, O.; Xu, M.; Liang, J.; Wang, Y.
10.1101/2023.04.21.537835 — cell biology — Posted on 2023-04-21
1168 DNA damage-induced interaction between a lineage addiction oncogenic transcription factor and the MRN complex shapes a tissue-specific DNA Damage Response and cancer predisposition
Binet, R.; Lambert, J.-P.; Tomkova, M.; Tischfield, S.; Baggiolini, A.; Picaud, S.; Sarkar, S.; Louphrasitthiphol, P.; Dias, D.; Carreira, S.; Humphrey, T. C.; Filippakopoulos, P.; White, R.; Goding, C. R.
10.1101/2023.04.21.537819 — molecular biology — Posted on 2023-04-21
1170 White matter plasticity during second language learning within and across hemispheres
Wei, X.; Gunter, T. C.; Adamson, H.; Schwendemann, M.; Friederici, A. D.; Goucha, T.; Anwander, A.
10.1101/2023.04.21.537810 — neuroscience — Posted on 2023-04-21
1172 Regulating microbiome metabolic stability for stable indigenous liquor fermentation
Tan, Y.; Zhu, Y.; wijffels, R.; scott, W.; Xu, Y.; Martins dos Santos, V. A. P.
10.1101/2023.04.21.537800 — systems biology — Posted on 2023-04-21
1174 Functional analysis of Salix purpurea genes support roles for ARR17 and GATA15 as master regulators of sex determination
Hyden, B.; Carper, D. L.; Abraham, P. E.; Yuan, G.; Yao, T.; Baumgart, L.; Zhang, Y.; Chen, C.; O'Malley, R.; Chen, J.-G.; Yang, X.; Hettich, R. L.; Tuskan, G. A.; Smart, L. B.
10.1101/2023.04.21.537837 — plant biology — Posted on 2023-04-21
1176 A Human Breast Cell Atlas Mapping the Homeostatic Cellular Shifts in the Adult Breast
Khaled, W. T.; Reed, A. D.; Pensa, S.; Steif, A.; Stenning, J.; Kunz, D.; He, P.; Twigger, A.-J.; Kania, K.; Barrow, R.; Goulding, I.; Gomm, J.; Jones, L.; Marioni, J.
10.1101/2023.04.21.537845 — cancer biology — Posted on 2023-04-21
1177 Protein family annotation for the Unified Human Gastrointestinal Proteome by DPCfam clustering
Barone, F.; Russo, E. T.; Villegas Garcia, E. N.; Punta, M.; Cozzini, S.; Ansuini, A.; Cazzaniga, A.
10.1101/2023.04.21.537802 — bioinformatics — Posted on 2023-04-21
1179 Mammary microvessels are sensitive to menstrual cycle sex hormones
Moccia, C.; Cherubini, M.; Fortea Guillamon, M.; Akinbote, A.; Padmanaban, P.; Beltran, V.; Haase, K.
10.1101/2023.04.21.537664 — bioengineering — Posted on 2023-04-21
1186 An in vitro experimental pipeline to characterize the binding specificity of SARS-CoV-2 neutralizing antibodies
Atanasoff, K. E.; Brambilla, L.; Adelsberg, D. C.; Kowdle, S. S.; Stevens, C. S.; Hung, C.-t.; Fu, Y.; Lim, R.; Tran, L.; Allen, R.; Duty, J. A.; Bajic, G.; Lee, B.; Tortorella, D.
10.1101/2023.04.20.537738 — microbiology — Posted on 2023-04-21
1187 Spatial enrichment of the type 1 interferon signature in the brain of a neuropsychiatric lupus murine model
Aw, E.; Lin, S. L.; Zhang, Y.; Herrmann, U.; Yalcin, E.; Langston, K.; Castrillion, C.; Ma, M.; Moffitt, J. R.; Carroll, M. C.
10.1101/2023.04.21.537814 — immunology — Posted on 2023-04-21
1188 Translating deep learning to neuroprosthetic control
Deo, D. R.; Willett, F. R.; Avansino, D. T.; Hochberg, L. R.; Henderson, J. M.; Shenoy, K. V.
10.1101/2023.04.21.537581 — neuroscience — Posted on 2023-04-21
1190 Multidimensional analysis of matched primary and recurrent glioblastoma identifies Fcgamma receptors upregulation on microglia as a contributor of tumor recurrence.
Shekarian, T.; Hogan, S.; Martins, T. A.; Schmassmann, P.; Gerber, A.; Roux, J.; Kaymak, D.; Durano, C.; Burger, B.; Matter, M.; Ritz, M.-F.; Hutter, G. A.
10.1101/2023.04.21.537308 — cancer biology — Posted on 2023-04-21
1193 Mapping host-microbe transcriptional interactions by dual perturb-seq
Butterworth, S.; Kordova, K.; Chandrasekaran, S.; Thomas, K. K.; Torelli, F.; Lockyer, E. J.; Edwards, A.; Goldstone, R.; Koshy, A. A.; Treeck, M.
10.1101/2023.04.21.537779 — molecular biology — Posted on 2023-04-21
1196 TUMOR ENDOTHELIAL CELL AUTOPHAGY IS A KEY VASCULAR-IMMUNE CHECKPOINT IN MELANOMA
Verhoeven, J.; Jacobs, K. A.; Rizzollo, F.; Lodi, F.; Hua, Y.; Pozniak, J.; Srinvasan, A. N.; Houbaert, D.; Shankar, G.; More, S.; Schaaf, M. B.; Dubroja Lakic, N.; Ganne, M.; Lamote, J.; Van Weyenbergh, J.; Boon, L.; Bechter, O.; Bosisio, F.; Bertrand, M.; Marine, J. C.; Lambrechts, D.; Bergers, G.; Agrawal, M.; Agostinis, P.
10.1101/2023.04.21.537799 — cancer biology — Posted on 2023-04-21
1206 COMPLETE GENOME SEQUENCE OF VIBRIO SYNGNATHI SP. NOV., A FISH PATHOGEN, ISOLATED FROM THE KIEL FJORD
Chibani, C. M.; Hertel, R.; Neumann-Schaal, M.; Goehlich, H.; Wagner, K.; Bunk, B.; Sproeer, C.; Overmann, J.; Hoppert, M.; Marten, M.; Roth, O.; Liesegang, H.; Wendling, C. C.
10.1101/2023.04.21.537764 — microbiology — Posted on 2023-04-21
1207 Visuomotor experience induces functional and structural plasticity of chandelier cells
Seignette, K.; Jamann, N.; Papale, P.; Terra, H.; Porneso, R. P. O.; de Kraker, L.; van der Togt, C.; van der Aa, M.; Neering, P.; Ruimschotel, E.; Roelfsema, P. R.; Montijn, J. S.; Self, M. W.; Kole, M. H. P.; Levelt, C. N.
10.1101/2023.04.21.537780 — neuroscience — Posted on 2023-04-21
1209 A Logic-incorporated Gene Regulatory Network Deciphers Principles in Cell Fate Decisions
Xue, G.; Zhang, X.; Li, W.; Zhang, L.; Zhang, Z.; Zhou, X.; Zhang, D.; Zhang, L.; Li, Z.
10.1101/2023.04.21.537440 — systems biology — Posted on 2023-04-21
1215 Compartmentation of photosynthesis gene expression between mesophyll and bundle sheath cells of C4 maize is dependent on time of day
Borba, R.; Reyna-Llorens, I.; Dickinson, P. J.; Steed, G.; Gouveia, P.; Gorska, A.; Gomes, C.; Kromdijk, J.; Webb, A. A.; Saibo, N.; Hibberd, J. M.
10.1101/2023.04.21.537465 — plant biology — Posted on 2023-04-21
1216 An isoform-resolution transcriptomic atlas of colorectal cancer from long-read single-cell sequencing
Li, Z.; Zhang, B.; Chan, J. J.; Tabatabaeian, H.; Tong, Q. Y.; Chew, X. H.; Fan, X.; Driguez, P.; Chan, C.; Cheong, F.; Wang, S.; Siew, B. E.; Tan, I. J.-W.; Lee, K. Y.; Lieske, B.; Cheong, W.-K.; Kappei, D.; Tan, K.-K.; Gao, X.; Tay, Y.
10.1101/2023.04.21.536771 — cancer biology — Posted on 2023-04-21
1217 Alternative splicing impacts microRNA regulation within coding regions
Hackl, L. M.; Fenn, A.; Louadi, Z.; Baumbach, J.; Kacprowski, T.; List, M.; Tsoy, O.
10.1101/2023.04.20.536398 — bioinformatics — Posted on 2023-04-21
1219 mitoSplitter: A mitochondrial variants-based method for efficient demultiplexing of pooled single-cell RNA-seq
Lin, X.; Chen, Y.; Lin, L.; Yin, K.; Cheng, R.; Wang, X.; Guo, Y.; Wu, Z.; Zhang, Y.; Li, J.; Yang, C.; Song, J.
10.1101/2023.04.16.537058 — bioinformatics — Posted on 2023-04-21
1221 Nociception in chicken embryos, Part III: Analysis of movements before and after application of a noxious stimulus
Suess, S. C.; Werner, J.; Saller, A. M.; Weiss, L.; Reiser, J.; Ondracek, J. M.; Zablotski, Y.; Kollmansperger, S.; Anders, M.; Schusser, B.; Fenzl, T.; Baumgartner, C.
10.1101/2023.04.20.537674 — animal behavior and cognition — Posted on 2023-04-21
1222 Enhancer evolution as a driving force for lineage-specific paralog usage in the central nervous system.
Fujimori, C.; Sugimoto, K.; Ishida, M.; Yang, C.; Kayo, D.; Tomihara, S.; Sano, K.; Akazome, Y.; Oka, Y.; Kanda, S.
10.1101/2023.04.20.537653 — evolutionary biology — Posted on 2023-04-21
1223 BATF relieves hepatic steatosis by inhibiting PD1 and promoting energy metabolism
Zhang, Z.; Liao, Q.; Pan, T.; Yu, L.; Luo, Z.; Su, S.; Liu, S.; Hou, M.; Li, Y.; Damba, T.; Liang, Y.; Zhou, L.
10.1101/2023.04.18.537352 — molecular biology — Posted on 2023-04-21
1224 Genetically diverse mouse models of SARS-CoV-2 infection reproduce clinical variation in type I interferon and cytokine responses in COVID-19
Robertson, S.; Bedard, O.; McNally, K.; Shaia, C.; Clancy, C.; Lewis, M.; Broeckel, R.; Chiramel, A.; Shannon, J. G.; Sturdevant, G.; Rosenke, R.; Anzick, S. L.; Forte, E.; Preuss, C.; Baker, C.; Harder, J.; Brunton, C.; Munger, S. C.; Bruno, D. P.; Lack, J. B.; Leung, J. M.; Shamsaddini, A.; Gardina, P.; Sturdevant, D.; Sun, J.; Martens, C.; Holland, S.; Rosenthal, N.; Best, S.
10.1101/2021.09.17.460664 — microbiology — Posted on 2023-04-21
1225 Relationship of maternal cytomegalovirus-specific antibody responses and viral load to vertical transmission risk following primary maternal infection in a rhesus macaque model
Otero, C. E.; Barfield, R.; Scheef, E.; Nelson, C. S.; Rodgers, N.; Wang, H.-Y.; Moström, M.; Manuel, T. D.; Sass, J.; Schmidt, K.; Taher, H.; Papen, C.; Sprehe, L.; Kendall, S.; Davalos, A.; Barry, P. A.; Früh, K.; Pollara, J.; Malouli, D.; Chan, C.; Kaur, A.; Permar, S. R.
10.1101/2023.04.21.537769 — immunology — Posted on 2023-04-21
1226 A multi-scale digital twin for adiposity-driven insulin resistance in humans: diet and drug effects
Herrgardh, T.; Simonsson, C.; Ekstedt, M.; Lundberg, P.; Stenkula, K. G.; Nyman, E.; Gennemark, P.; Cedersund, G.
10.1101/2023.04.20.537480 — systems biology — Posted on 2023-04-21
1228 Heat stress impairs centromere structure and segregation of meiotic chromosomes in Arabidopsis
Crhak Khaitova, L.; Mikulkova, P.; Pecinkova, J.; Kalidass, M.; Heckmann, S.; Lermontova, I.; Riha, K.
10.1101/2023.04.19.537519 — plant biology — Posted on 2023-04-21
1229 Characterization of Tryptophan Oxidation Affecting D1 Degradation by FtsH in the Photosystem II Quality Control of Chloroplasts
Kato, Y.; Kuroda, H.; Ozawa, S.-I.; Saito, K.; Dogra, V.; Scholz, M.; Zhang, G.; de Vitry, C.; Ishikita, H.; Kim, C.; Hippler, M.; Takahashi, Y.; Sakamoto, W.
10.1101/2023.04.20.537607 — plant biology — Posted on 2023-04-21
1230 Regulation of apico-basolateral trafficking polarity of homologous Copper-ATPases ATP7A and ATP7B
Gupta, A.; Ruturaj, ; Mishra, M.; Saha, S.; Maji, S.; Rodriguez-Boulan, E.; Schreiner, R.
10.1101/2023.04.19.537613 — cell biology — Posted on 2023-04-21
1232 Pharmacological Induction of mesenchymal-epithelial transition chemosensitizes breast cancer cells and prevents metastatic progression
Bagheri, M.; Mohamed, G. A.; Mohamed Saleem, M. A.; Ognjenovic, N. B.; Lu, H.; Kolling, F. W.; Wilkins, O. M.; Das, S.; LaCroix, I. S.; Nagaraj, S. H.; Muller, K. E.; Gerber, S. A.; Miller, T. W.; Pattabiraman, D. R.
10.1101/2023.04.19.537586 — cancer biology — Posted on 2023-04-21
1242 Establishment of a screening platform based on human coronavirus OC43 for the identification of microbial natural products with antiviral activity
Martinez-Arribas, B.; Annang, F. B.; Diaz-Gonzalez, R.; Perez-Moreno, G.; Martin, J.; Mackenzie, T. A.; Castillo, F.; Reyes, F.; Genilloud, O.; Ruiz-Perez, L. M.; Vicente, F.; Ramos, M. C.; Gonzalez-Pacanowska, D.
10.1101/2023.04.20.537680 — microbiology — Posted on 2023-04-21
1244 GLYCOLYTIC REPROGRAMMING FUELS MYELOID CELL-DRIVEN HYPERCOAGULABILITY
Rehill, A. M.; Leon, G.; McCluskey, S.; Schoen, I.; Hernandez-Santana, Y.; Annett, S. L.; Klavina, P.; Robson, T.; Curtis, A. M.; Renne, T.; Hussey, S.; O'Donnell, J. S.; Walsh, P. T.; Preston, R. J.
10.1101/2023.04.20.537683 — immunology — Posted on 2023-04-21
1245 Unpacking the functional heterogeneity of the Emotional Face Matching Task: a normative modelling approach
Savage, H. S.; Mulders, P. C. R.; van Eijndhoven, P. F. P.; van Oort, J.; Tendolkar, I.; Vrijsen, J. N.; Beckmann, C. F.; Marquand, A. F.
10.1101/2023.03.27.534351 — neuroscience — Posted on 2023-04-21
1247 Galectin-3 Mediates Vascular Dysfunction in Obesity by Regulating NADPH Oxidase 1
Padgett, C. A.; Batori, R. K.; Speese, A. C.; Rosewater, C. L.; Bush, W. B.; Derella, C. C.; Haigh, S.; Sellers, H. G.; Corley, Z. L.; West, M. A.; Mintz, J. D.; Ange, B.; Harris, R. A.; Brands, M. W.; Fulton, D. J. R.; Stepp, D. W.
10.1101/2023.04.19.537592 — physiology — Posted on 2023-04-21
1248 Circulating neutrophils from patients with early breast cancer have distinct subtype-dependent phenotypes
Ramessur, A.; Ambasager, B.; Aramburu, I. V.; Peakman, F.; Gleason, K.; Lehmann, C.; Papayannopoulos, V.; Coombes, C.; Malanchi, I.
10.1101/2023.04.19.537022 — cancer biology — Posted on 2023-04-21
1249 A core Nrf2 gene set defined through comprehensive transcriptomic analysis predicts drug resistance and poor multi-cancer prognosis
Luo, G.; Kumar, H.; Alridge, K.; Rieger, S.; Jiang, E.; Chan, E. R.; Soliman, A.; Mahdi, H.; Letterio, J. J.
10.1101/2023.04.20.537691 — cancer biology — Posted on 2023-04-21
1250 p73 activates transcriptional signatures of basal lineage identity and ciliogenesis in pancreatic ductal adenocarcinoma
Hur, S. K.; Somerville, T. D. D.; Wu, X. S.; Maia-Silva, D.; Demerdash, O. E.; Tuveson, D. A.; Notta, F.; Vakoc, C. R.
10.1101/2023.04.20.537667 — cancer biology — Posted on 2023-04-21
1251 ATOMDANCE: interpretable kernel-based learning for denoising functional and evolutionary comparisons of protein dynamics
Babbitt, G. A.; Rajendran, M.; Lynch, M. L.; Asare-Bediako, R.; Mouli, L. T.; Ryan, C. J.; Srivastava, H.; Phadke, K.; Reed, M. L.; Moore, N.; Ferran, M. C.; Fokoue, E. P.
10.1101/2023.04.20.537698 — biophysics — Posted on 2023-04-21
1256 Multiplexed Sequential Imaging in Living Cells with Orthogonal Fluorogenic RNA Aptamer/Dye Pairs
Zheng, R.; Wu, R.; Liu, Y.; Sun, Z.; Bagheri, Y.; Xue, Z.; Mi, L.; Tian, Q.; Pho, R.; Siddiqui, S.; Ren, K.; You, M.
10.1101/2023.04.20.537750 — bioengineering — Posted on 2023-04-21
1263 The distribution, phenology, host range and pathogen prevalence of Ixodes ricinus in France: a systematic map and narrative review
Perez, G.; Bournez, L.; Boulanger, N.; Fite, J.; Livoreil, B.; McCoy, K. D.; Quillery, E.; Rene-Martellet, M.; Bonnet, S. I.
10.1101/2023.04.18.537315 — ecology — Posted on 2023-04-21
1265 Vertical transmission of maternal mitochondrial DNA through extracellular vesicles modulates embryo bioenergetics
Bolumar, D.; Moncayo-Arlandi, J.; Gonzalez-Fernandez, J.; Ochando, A.; Moreno, I.; Marin, C.; Diez, A.; Fabra, P.; Checa, M. A.; Espinos, J. J.; Gardner, D. K.; Simon, C.; Vilella, F.
10.1101/2023.04.21.537765 — developmental biology — Posted on 2023-04-21
1266 The Role of MAP3K1 in the Development of the Female Reproductive Tract
Kimura, E.; Mongan, M.; Xiao, B.; Wang, J.; Carreira, V. S.; Bolon, B.; Zhang, X.; Burns, K. A.; Biesiada, J.; Medvedovic, M.; Puga, A.; Xia, Y.
10.1101/2023.04.20.537715 — developmental biology — Posted on 2023-04-21
1267 Pannexin-1 channels promote CD8+ T cell effector and memory responses through distinct intracellular pathways
Vardam-Kaur, T.; Banuelos, A.; Gabaldon-Parish, M.; Wanhainen, K. M.; Zhou, M. H.; van Dijk, S.; Macedo, B. G.; Salgado, C. L.; Santiago-Carvalho, I.; Peng, C.; Jameson, S. C.; Borges da Silva, H.
10.1101/2023.04.19.537580 — immunology — Posted on 2023-04-21
1268 Altered X-chromosome inactivation predisposes to autoimmune manifestations in mice
Huret, C.; David, A.; Mohamed, M.; Valentin, N.; Charlotte, F.; Goodhardt, M.; Rougeulle, C.; Morey, C.
10.1101/2023.04.20.537662 — immunology — Posted on 2023-04-21
1269 Antagonistic nanobodies reveal mechanism of GSDMD pore formation and unexpected therapeutic potential
Schiffelers, L. D. J.; Normann, S.; Binder, S. C.; Hagelauer, E.; Kopp, A.; Alon, A.; Geyer, M.; Ploegh, H. L.; Schmidt, F. I.
10.1101/2023.04.20.537718 — immunology — Posted on 2023-04-21
1270 Nucleus accumbens neurons dynamically encode positive and aversive associative learning
Deseyve, C.; Domingues, A. V.; Carvalho, T. T. A.; Vieitas-Gaspar, N.; Pinto, L.; Sousa, N.; Coimbra, B.; Rodrigues, A. J.; Soares-Cunha, C.
10.1101/2023.04.21.537763 — neuroscience — Posted on 2023-04-21
1271 Exogenous TGFβ1 and its mimic HpTGM attenuate the heart's inflammatory response to ischaemic injury and improve long term cardiac outcomes
Redgrave, R. E.; Singh, E.; Tual-Chalot, S.; Park, C.; Hall, D.; Bannaceur, K.; Smyth, D.; Maizels, R. M.; Spyridopoulos, I.; Arthur, H. M.
10.1101/2023.04.18.537417 — pathology — Posted on 2023-04-21
1272 Dosimetric and biologic intercomparison between electron and proton FLASH beams
Almeida, A.; Togno, M.; Ballesteros-Zebadua, P.; Franco-Perez, J.; Geyer, R.; Schaefer, R.; Petit, B.; Grilj, V.; Meer, D.; Safai, S.; Lomax, T.; Weber, D. C.; Bailat, C.; Psoroulas, S.; Vozenin, M.-c.
10.1101/2023.04.20.537497 — cancer biology — Posted on 2023-04-21
1274 Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas
Hariharan, S.; Whitfield, B. T.; Pirozzi, C. J.; Waitkus, M. S.; Brown, M. C.; Bowie, M. L.; Irvin, D. M.; Roso, K.; Fuller, R.; Hostettler, J.; Dharmaiah, S.; Gibson, E. A.; Briley, A.; Mangoli, A.; Fraley, C.; Shobande, M.; Stevenson, K.; Zhang, G.; Malgulwar, P. B.; Roberts, H.; Roskoski, M.; Spasojevic, I.; Keir, S. T.; He, Y.; Castro, M. G.; Huse, J. T.; Ashley, D. M.
10.1101/2023.04.20.537594 — cancer biology — Posted on 2023-04-21
1275 A minimal physical model for curvotaxis driven by curved protein complexes at the cell's leading edge
Sadhu, R. K.; Luciano, M.; Xi, W.; Torres, C. M.; Schroder, M.; Blum, C.; Tarantola, M.; Penic, S.; Iglic, A.; Beta, C.; Steinbock, O.; Bodenschatz, E.; Ladoux, B.; GABRIELE, S.; Gov, N.
10.1101/2023.04.19.537490 — biophysics — Posted on 2023-04-21
1277 CellHeap: A scRNA-seq workflow for large-scalebioinformatics data analysis
Castro, M. C.; Silva, V. S.; Costa, M. O.; Silva, H. S.; Walter, M. E.; Melo, A.; Ocana, K.; dos Santos, M. T.; Nicolas, M. F.; Carvalho, A. C.; Pons, A. H.; Silva, F. A. B.
10.1101/2023.04.19.537508 — bioinformatics — Posted on 2023-04-21
1279 The Promise and Pitfalls of Prophages
McKerral, J. C.; Nalagampalli Papudeshi, B.; Inglis, L. K.; Roach, M. J.; Decewicz, P.; McNair, K.; Luque, A.; Dinsdale, E. A.; Edwards, R. A.
10.1101/2023.04.20.537752 — bioinformatics — Posted on 2023-04-21
1282 Kronos: A computational tool to facilitate biological rhythmicity analysis
Bastiaanssen, T. F. S.; Leigh, S.-J.; Tofani, G. S. S.; Gheorghe, C. E.; Clarke, G.; Cryan, J. F.
10.1101/2023.04.21.537503 — bioinformatics — Posted on 2023-04-21
1283 Fibertools: fast and accurate DNA-m6A calling using single-molecule long-read sequencing
Jha, A.; Bohaczuk, S. C.; Mao, Y.; Ranchalis, J.; Mallory, B. J.; Min, A. T.; Hamm, M. O.; Swanson, E.; Finkbeiner, C.; Li, T.; Whittington, D.; Noble, W. S.; Stergachis, A. B.; Vollger, M. R.
10.1101/2023.04.20.537673 — bioinformatics — Posted on 2023-04-21
1284 D-SPIN constructs gene regulatory network models from multiplexed scRNA-seq data revealing organizing principles of cellular perturbation response
Jiang, J.; Chen, S.; Tsou, T.; McGinnis, C. S.; Khazaei, T.; Zhu, Q.; Park, J. H.; Strazhnik, I.-M.; Hanna, J.; Chow, E. D.; Sivak, D. A.; Gartner, Z. J.; Thomson, M.
10.1101/2023.04.19.537364 — bioinformatics — Posted on 2023-04-21
1286 Feature-Based 3D+t Descriptors of Hyperactivated Human Sperm Beat Patterns
Hernandez-Avina, H. O.; Montoya, F.; Hernandez-Herrera, P.; Diaz-Guerrero, D. S.; Olveres, J.; Darszon, A.; Escalante-Ramirez, B.; CORKIDI, G.
10.1101/2023.04.20.537721 — bioengineering — Posted on 2023-04-21
1290 Tailored chemical reactivity probes for systemic imaging of aldehydes in fibroproliferative diseases
Ma, H.; Zhou, I. Y.; Chen, Y. I.; Rotile, N. J.; Ay, I.; Akam, E.; Wang, H.; Knipe, R.; Hariri, L. P.; Zhang, C.; Drummond, M.; Pantazopoulos, P.; Moon, B. F.; Boice, A. T.; Zygmont, S. E.; Werigand-Whittier, J.; Sojoodi, M.; Gonzalez-Villalobos, R. A.; Hansen, M. K.; Tanabe, K. K.; Caravan, P.
10.1101/2023.04.20.537707 — biochemistry — Posted on 2023-04-21
1291 Multiparametric domain insertional profiling of Adeno-Associated Virus VP1
Hoffmann, M. D.; Zdechlik, A. C.; He, Y.; Nedrud, D.; Aslanidi, G.; Gordon, W.; Schmidt, D.
10.1101/2023.04.19.537549 — biochemistry — Posted on 2023-04-21
1292 Structural rather than catalytic role for mitochondrial respiratory chain supercomplexes
Brischigliaro, M.; Cabrera-Orefice, A.; Arnold, S.; Viscomi, C.; Zeviani, M.; Fernandez-Vizarra, E.
10.1101/2023.04.19.537447 — biochemistry — Posted on 2023-04-21
1294 Extreme structural heterogeneity rewires glioblastoma chromosomes to sustain patient-specific transcriptional programs
Xie, T.; Danieli-Mackay, A.; Buccarelli, M.; Barbieri, M.; Papadionysiou, I.; D'Alessandris, G.; Uebelmesser, N.; Vinchure, O. S.; Lauretti, L.; Fotia, G.; Wang, X.; Ricci-Vitiani, L.; Gopalakrishnan, J.; Pallini, R.; Papantonis, A.
10.1101/2023.04.20.537702 — genomics — Posted on 2023-04-21
1295 Nanoparticle Enrichment Mass-Spectrometry Proteomics Identifies Protein Altering Variants for Precise pQTL Mapping
Suhre, K.; Venkataraman, G. R.; Guturu, H.; Halama, A.; Stephan, N.; Thareja, G.; Sarwath, H.; Motamedchaboki, K.; Donovan, M.; Siddiqui, A.; Batzoglou, S.; Schmidt, F.
10.1101/2023.04.20.537640 — genomics — Posted on 2023-04-21
1299 Genetic basis of aposematic coloration in a mimetic radiation of poison frogs
Linderoth, T.; Aguilar-Gomez, D.; White, E.; Twomey, E.; Stuckert, A.; Bi, K.; Ko, A.; Graham, N.; Rocha, J. L.; Chang, J.; MacManes, M. D.; Summers, K.; Nielsen, R.
10.1101/2023.04.20.537757 — evolutionary biology — Posted on 2023-04-21
1300 Functional and historical drivers of leaf shape evolution in Palms (Arecaceae)
Jimenez, M. F. T.; Chazot, N.; Emilio, T.; Fredin, J. U.; Antonelli, A.; Faurby, S.; Bacon, C. D.
10.1101/2021.10.26.465896 — evolutionary biology — Posted on 2023-04-21
1301 Comparative genome microsynteny illuminates the fast evolution of nuclear mitochondrial segments (NUMTs) in mammals
Uvizl, M.; Puechmaille, S. J.; Power, S.; Pippel, M.; Carthy, S.; Haerty, W.; Myers, E. W.; Teeling, E. C.; Huang, Z.
10.1101/2023.04.20.537758 — evolutionary biology — Posted on 2023-04-21
1304 Data-driven prediction of colonization outcomes for complex microbial communities
Wu, L.; Wang, X.-W.; Tao, Z.; Wang, T.; Zuo, W.; Zeng, Y.; Liu, Y.-Y.; Dai, L.
10.1101/2023.04.19.537502 — ecology — Posted on 2023-04-21
1305 Camera trap methods and drone thermal surveillance provide reliable, comparable density estimates of large, free-ranging ungulates
Baldwin, R. W.; Beaver, J. T.; Messinger, M.; Muday, J.; Windsor, M.; Larsen, G. D.; Silman, M. R.; Anderson, T. M.
10.1101/2023.04.20.537687 — ecology — Posted on 2023-04-21
1306 Time, Space and Single-Cell Resolved Molecular Trajectory of Cell Populations and the Laterality of the Body Plan at Gastrulation
Wang, R.; Yang, X.; Chen, J.; Zhang, L.; Griffiths, J. A.; Cui, G.; Chen, Y.; Qian, Y.; Peng, G.; Li, J.; Wang, L.; Marioni, J.; Tam, P.; Jing, N.
10.1101/2023.04.19.537134 — developmental biology — Posted on 2023-04-21
1308 DCBLD1 modulates angiogenesis by regulating of the VEGFR-2 endocytosis in endothelial cells
Feng, Q.; Guo, L.; Yu, C.; Liu, X.; Lin, Y.-L. Y.; Li, C.; Zhang, W.; Zong, Y.; Yang, W.; Ma, Y.; Wang, R.; Li, L.; Pei, Y.; Wang, H.-F.; Liu, D.; Han, M.; Niu, H.; Nie, L.
10.1101/2023.04.20.537746 — molecular biology — Posted on 2023-04-21
1309 Disease Tolerance Acquired Through Repeated Plasmodium Infection Involves Epigenetic Reprogramming of Innate Immune Cells
Nideffer, J.; Ty, M.; Donato, M.; Rek, J.; Kajubi, R.; Ji, X.; Maecker, H.; Nankya, F.; Musinguzi, K.; Press, K.; Greenhouse, B.; Kamya, M.; Feeney, M. E.; Dorsey, G.; Utz, P.; Pulendran, B.; Khatri, P.; Jagannathan, P.
10.1101/2023.04.19.537546 — immunology — Posted on 2023-04-21
1310 Virally induced lipid droplets are a platform for innate immune signalling complexes
Monson, E. A.; Laws, J. L.; Telikani, Z.; Milligan, A. J.; Rozario, A. M.; Amarasinghe, I.; Smith, M. L.; Tran, V.; Dinh, Q.; Williamson, N. A.; Mechler, A.; Johnson, C.; Hofer, M. J.; Nie, S.; Whelan, D. R.; Helbig, K. J.
10.1101/2023.04.20.537741 — immunology — Posted on 2023-04-21
1311 Metabolic Reprogramming via targeting ACOD1 promotes polarization and anti-tumor activity of human CAR-iMACs in solid tumors
Wang, X.; Su, S.; Zhu, Y.; Cheng, X.; Chen, C.; Chen, L.; Lei, A.; Zhang, L.; Xu, Y.; Li, W.; Zhang, Y.; Ye, D.; ZHANG, J.
10.1101/2023.04.20.537647 — immunology — Posted on 2023-04-21
1312 Alterations in cortical excitability during pain: A combined TMS-EEG Study
Chowdhury, N. S.; Chiang, A. K.; Millard, S. K.; Skippen, P.; Chang, W.-J.; Seminowicz, D. A.; Schabrun, S. M.
10.1101/2023.04.20.537735 — neuroscience — Posted on 2023-04-21
1313 Cues for predictive eye movements in naturalistic scenes
Goettker, A.; Borgerding, N.; Leeske, L.; Gegenfurnter, K. R.
10.1101/2023.04.21.537766 — neuroscience — Posted on 2023-04-21
1315 Age-dependent ventilator-induced lung injury: Mathematical modeling, experimental data, and statistical analysis
Hay, Q.; Grubb, C.; Minucci, S.; Valentine, M. S.; Van Mullekom, J.; Heise, R. L.; Reynolds, A. M.
10.1101/2023.04.20.537614 — systems biology — Posted on 2023-04-21
1319 The genome of Talinum fruticosum
Brilhaus, D.; Denton, A. K.; Maleckova, E.; Reichel-Deland, V.; Weber, A. P. M.
10.1101/2023.04.20.537669 — plant biology — Posted on 2023-04-21
1322 Nfe2l1-mediated proteasome function controls muscle energy metabolism in obesity
Lemmer, I. L.; Haas, D. T.; Willemsen, N.; Kotschi, S.; Toksoez, I.; Gjika, E.; Khani, S.; Rohm, M.; Diercksen, N.; Nguyen, P. B. H.; Menden, M. P.; Egu, D. T.; Waschke, J.; Larsen, S.; Ma, T.; Gerhart-Hines, Z.; Herzig, S.; Dyar, K.; Krahmer, N.; Bartelt, A.
10.1101/2023.04.20.537611 — physiology — Posted on 2023-04-21
1323 Validating a low-cost, open-source, locally manufactured workstation and computational pipeline for automated histopathology evaluation using deep learning
Choudhury, D.; Dolezal, J.; Dyer, E.; Kochanny, S.; Ramesh, S.; Howard, F. M.; Margalus, J. R.; Schroeder, A.; Schulte, J. J.; Garassino, M. C.; Kather, J. N.; Pearson, A. T.
10.1101/2023.04.19.537544 — pathology — Posted on 2023-04-21
1324 CRACD suppresses neuroendocrinal plasticity of lung adenocarcinoma
Kim, B.; Zhang, S.; Huang, Y.; Ko, K.-P.; Zou, G.; Zhang, J.; Jun, S.; Kim, K.-B.; Jung, Y.-S.; PARK, K.-S.; Park, J.-I.
10.1101/2023.04.19.537576 — cancer biology — Posted on 2023-04-21
1325 Retinoids and EZH2 inhibitors cooperate to orchestrate cytotoxic effects on bladder cancer cells
Ozgun, G.; Yaras, T.; Landman, N.; Karakulah, G.; van Lohuizen, M. M. S.; Senturk, S.; Erkek Ozhan, S.
10.1101/2023.04.19.537500 — cancer biology — Posted on 2023-04-21
1327 Vimentin intermediate filaments structure and mechanically support microtubules in cells
Blob, A.; Ventzke, D.; Nies, G.; Dühmert, J. N.; Schmitzer, B.; Munk, A.; Schaedel, L.; Köster, S.
10.1101/2023.04.19.537509 — biophysics — Posted on 2023-04-21
1328 Energetic driving force for LHCII clustering in plant membranes
Manna, P.; Hoffmann, M.; Davies, T.; Richardson, K. H.; Johnson, M. P.; Schlau-Cohen, G. S.
10.1101/2023.04.19.537479 — biophysics — Posted on 2023-04-21
1332 Immune cells employ traction forces to overcome steric hindrance in 3D biopolymer networks
Czerwinski, T.; Bischof, L.; Böhringer, D.; Kara, S.; Wittmann, E.; Winterl, A.; Gerum, R.; Nusser, G.; Wiesinger, M.; Budday, S.; Lux, A.; Voskens, C.; Fabry, B.; Mark, C.
10.1101/2023.04.20.537658 — biophysics — Posted on 2023-04-21
1335 Scoary2: Rapid association of phenotypic multi-omics data with microbial pan-genomes
Roder, T.; Pimentel, G.; Fuchsmann, P.; Tena Stern, M.; von Ah, U.; Vergeres, G.; Peischl, S.; Brynildsrud, O.; Bruggmann, R.; Baur, C.
10.1101/2023.04.19.537353 — bioinformatics — Posted on 2023-04-21
1340 A novel injectable radiopaque hydrogel with potent properties for multicolor CT imaging in the context of brain and cartilage regenerative therapy
Said, M.; Tavakoli, C.; Dumot, C.; Toupet, K.; Dong, Y. C.; Collomb, N.; Auxenfans, C.; Moisan, A.; Favier, B.; Chovelon, B.; Barbier, E. L.; Jorgensen, C.; Cormode, D. P.; Noel, D.; Brun, E.; Elleaume, H.; Wiart, M.; Detante, O.; Rome, C.; Auzely-Velty, R.
10.1101/2023.04.20.537520 — bioengineering — Posted on 2023-04-21
1341 Stitching flexible electronics into the brain
Lee, J. M.; Lin, D.; Pyo, Y.-W.; Kim, H.-R.; Park, H.-G.; Lieber, C. M.
10.1101/2023.04.20.537740 — bioengineering — Posted on 2023-04-21
1343 DECODING COMPLEXITY IN BIOMOLECULAR RECOGNITION OF DNA I-MOTIFS
Yazdani, K.; Seshadri, S.; Tillo, D.; Vinson, C.; Schneekloth, J. S.
10.1101/2023.04.19.537548 — biochemistry — Posted on 2023-04-21
1345 A chromosome scale genome assembly and evaluation of mtDNA variation in the willow leaf beetle Chrysomela aeneicollis
Bracewell, R. R.; Stillman, J.; Dahlhoff, E.; Smeds, E.; Chatla, K.; Bachtrog, D.; Williams, C.; Rank, N.
10.1101/2023.04.19.537531 — genomics — Posted on 2023-04-21
1346 Altered neutrophil extracellular traps in response to Mycobacterium tuberculosis in persons living with HIV with no previous TB and negative TST and IGRA
Kroon, E. E.; Correa de Macedo, W.; Evans, R.; Seeger, A.; Engelbrecht, L.; Kriel, J.; Loos, B.; Okugbeni, N.; Orlova, M. O.; Cassart, P.; Kinnear, C.; Tromp, G.; Moller, M.; Wilkinson, R. J.; Coussens, A. K.
10.1101/2023.04.19.537498 — genetics — Posted on 2023-04-21
1348 LeishMANIAdb: a comparative resource for Leishmania proteins
Tusnady, G. E.; Zeke, A.; Kalman, Z. E.; Fatoux, M.; Ricard-Blum, S.; Gibson, T. J.; Dobson, L.
10.1101/2023.03.08.531706 — bioinformatics — Posted on 2023-04-21
1351 Decoding human in vitro terminal erythropoiesis originating from umbilical cord blood mononuclear cells and pluripotent stem cells
Wang, X.; Zhang, W.; Zhao, S.; Yan, H.; Xin, Z.; Cui, T.; Zang, R.; Zhao, L.; Wang, H.; Zhou, J.; Li, X.; Yue, W.; Xi, J.; Zhang, Z.; Fang, X.; Pei, X.
10.1101/2023.04.20.537628 — cell biology — Posted on 2023-04-21
1354 Mixed selectivity coding of content-temporal detail by dorsomedial posterior parietal neurons
Wang, L.; Zhou, X.; Zeng, F.; Cao, M.; Zuo, S.; Yang, J.; Kusunoki, M.; Wang, H.; Zhou, Y.-d.; Chen, A.; Kwok, S. C.
10.1101/2022.07.16.500237 — neuroscience — Posted on 2023-04-21
1355 Modelling human KCNT1-epilepsy in Drosophila: a seizure phenotype and drug responses
Hussain, R.; Lim, C. X.; Shaukat, Z.; Islam, A.; Caseley, E.; Lippiat, J. D.; Rychkov, G.; Ricos, M. G.; Dibbens, L. M.
10.1101/2023.04.11.536495 — neuroscience — Posted on 2023-04-21
1357 Arabidopsis thaliana subclass I ACTIN DEPOLYMERIZING FACTORs regulate nuclear organization and gene expression
Matsumoto, T.; Higaki, T.; Takatsuka, H.; Kutsuna, N.; Ogata, Y.; Hasezawa, S.; Umeda, M.; Inada, N.
10.1101/2023.04.19.537409 — cell biology — Posted on 2023-04-21
1358 ER structural remodeling requires TAK1/ATAT1-induced microtubule acetylation
Ortiz, H. R.; Flores, P. C.; Ramonett, A.; Ahmed, T.; Ellis, N. A.; Langlais, P. R.; Karthikeyan, M.; Lee, N. Y.
10.1101/2023.04.20.537623 — cell biology — Posted on 2023-04-21
1359 Mapping rhodopsin trafficking in rod photoreceptors with quantitative super-resolution microscopy
Haggerty, K. N.; Eshelman, S. C.; Sexton, L. A.; Frimpong, E.; Rogers, L. M.; Agosto, M. A.; Robichaux, M. A.
10.1101/2023.04.20.537413 — cell biology — Posted on 2023-04-21
1360 The spectral underpinnings of pathogen spread on animal networks
Fountain-Jones, N. M.; Silk, M.; Appaw, R.; Hamede, R.; Rushmore, J.; VanderWaal, K.; Craft, M. E. M.; Carver, S.; Charleston, M.
10.1101/2022.07.28.501936 — ecology — Posted on 2023-04-20
1362 Pyroptosis inhibiting nanobodies block Gasdermin D pore formation
Kopp, A.; Hagelueken, G.; Jamitzky, I.; Moecking, J.; Schiffelers, L. D. J.; Schmidt, F. I.; Geyer, M.
10.1101/2023.04.20.537705 — biochemistry — Posted on 2023-04-20
1363 Conservation of chromatin organization within human and primate centromeres
Dubocanin, D.; Cortes, A. E. S.; Hartley, G. A.; Ranchalis, J. E.; Agarwal, A.; Logsdon, G.; Munson, K. M.; Real, T. D.; Mallory, B. J.; Eichler, E. E.; O'Neill, R. J.; Stergachis, A. B.
10.1101/2023.04.20.537689 — genomics — Posted on 2023-04-20
1369 Suprabasal cells retaining stem cell identity programs drive basal cell hyperplasia in eosinophilic esophagitis
Clevenger, M. H.; Karami, A. L.; Carlson, D.; Kahrilas, P.; Gonsalves, N.; Pandolfino, J.; Winter, D.; Whelan, K. A.; Tetreault, M.-P.
10.1101/2023.04.20.537495 — molecular biology — Posted on 2023-04-20
1370 Transcription promotes the restoration of chromatin following DNA replication.
Bandau, S.; Alvarez, V.; Jiang, H.; Graff, S.; Sundaramoorthy, R.; Toman, M.; Owen-Hughes, T.; Sidoli, S.; Lamond, A. I.; Alabert, C.
10.1101/2023.04.19.537523 — molecular biology — Posted on 2023-04-20
1371 Convergence of multiple RNA-silencing pathways on GW182/TNRC6
Welte, T.; Goulois, A.; Stadler, M. B.; Hess, D.; Soneson, C.; Neagu, A.; Azzi, C.; Lübke, M. J.; Seebacher, J.; Schmidt, I.; Estoppey, D.; Nigsch, F.; Reece-Hoyes, J.; Hoepfner, D.; Grosshans, H.
10.1101/2023.04.20.537632 — molecular biology — Posted on 2023-04-20
1372 Single cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, ageing and disease
Kilfeather, P.; Khoo, J. H.; Wagner, K.; Liang, H.; Caiazza, M.-C.; An, Y.; Zhang, X.; Chen, X.; Connor-Robson, N.; Shang, Z.; Wade-Martins, R.
10.1101/2023.04.20.537553 — molecular biology — Posted on 2023-04-20
1373 Myosin Light Chain Dephosphorylation by PPP1R12C Promotes Atrial Hypocontractility in Atrial Fibrillation
McCauley, M. D.; Perike, S.; Gonzalez-Gonzalez, F. J.; Abu-Taha, I.; Damen, F.; Lizama, K. S.; Aboonabi, A.; Capote, A. E.; Aguilar-Torres, Y.; Levin, B.; Han, Z.; Sridhar, A.; Grand, J.; Martin, J.; Akar, J. G.; Warren, C. M.; Solaro, R. J.; Ong, S.-G.; Darbar, D.; Goergen, C. J.; Wolska, B. M.; Dobrev, D.; Wehrens, X. H.
10.1101/2023.04.19.537590 — molecular biology — Posted on 2023-04-20
1375 Sialoglycan binding triggers spike opening in a human coronavirus
Pronker, M. F.; Creutznacher, R.; Drulyte, I.; Hulswit, R. J. G.; Li, Z.; van Kuppeveld, F. J. M.; Snijder, J.; Lang, Y.; Bosch, B.-J.; Boons, G.-J.; Frank, M.; de Groot, R. J.; Hurdiss, D. L.
10.1101/2023.04.20.536837 — microbiology — Posted on 2023-04-20
1376 Genomic markers of drug resistance in Mycobacterium tuberculosis populations with minority variants
Zhang, X.; Lam, C.; Martinez, E.; Sim, E.; Crighton, T.; Marais, B. J.; Sintchenko, V.
10.1101/2023.04.19.537555 — microbiology — Posted on 2023-04-20
1380 Dynamic calcium-mediated stress response and recovery signatures in the fungal pathogen, Candida albicans
Giuraniuc, C. V.; Parkin, C.; Cruz Almeida, M.; Fricker, M.; Shadmani, P.; Nye, S.; Wehmeier, S.; Chawla, S.; Bedekovic, T.; Lehtovirta-Morley, L.; Richards, D.; Gow, N. A. R.; Brand, A. C.
10.1101/2023.04.20.537637 — microbiology — Posted on 2023-04-20
1381 Simultaneous tracking of near-isogenic bacterial strains in synthetic Arabidopsis microbiota by chromosomally-integrated barcodes
Ordon, J.; Thouin, J.; Nakano, R. T.; Ma, K.-W.; Zhang, P.; Huettel, B.; Garrido-Oter, R.; Schulze-Lefert, P.
10.1101/2023.04.20.537712 — microbiology — Posted on 2023-04-20
1382 Structure and assembly of a bacterial gasdermin pore
Johnson, A. G.; Mayer, M. L.; Schaefer, S. L.; McNamara-Bordewick, N. K.; Hummer, G.; Kranzusch, P. J.
10.1101/2023.04.20.537723 — microbiology — Posted on 2023-04-20
1384 Single-cell transcriptomics of resected human traumatic brain injury tissues reveals acute activation of endogenous retroviruses in oligodendroglia
Garza, R.; Sharma, Y.; Atacho, D.; Thiruvalluvan, A.; Hamdeh, S. A.; Jonsson, M. E.; Horvath, V.; Ingelsson, M.; Jern, P.; Hammell, M. G.; Englund, E.; Kirkeby, A.; Jakobsson, J.; Marklund, N.
10.1101/2022.09.07.506982 — neuroscience — Posted on 2023-04-20
1385 Revealing the Grammar of Small RNA Secretion Using Interpretable Machine Learning
Zirak, B.; Naghipourfar, M.; Saberi, A.; Pouyabahar, D.; Zarezadeh, A.; Luo, L.; Fish, L.; Huh, D.; Navickas, A.; Sharifi-Zarchi, A.; Goodarzi, H.
10.1101/2023.04.04.535452 — systems biology — Posted on 2023-04-20
1386 BayFlux: A Bayesian method to quantify metabolic Fluxes and their uncertainty at the genome scale
Backman, T. W. H.; Schenk, C.; Radivojevic, T.; Ando, D.; Singh, J.; Czajka, J. J.; Costello, Z.; Keasling, J. D.; Tang, Y.; Akhmatskaya, E.; Garcia Martin, H.
10.1101/2023.04.19.537435 — systems biology — Posted on 2023-04-20
1387 The Circadian Clock is Disrupted in Pancreatic Cancer
Schwartz, P. B.; Nukaya, M.; Berres, M.; Rubinstein, C. D.; Wu, G.; Hogenesch, J.; Bradfield, C.; Ronnekleiv-Kelly, S.
10.1101/2022.11.01.514735 — cancer biology — Posted on 2023-04-20
1389 Reduction of Paraoxonase expression followed by inactivation across independent semiaquatic mammals suggests stepwise path to pseudogenization
Graham, A. M.; Jamison, J. M.; Bustos, M.; Cournoyer, C.; Michaels, A.; Presnell, J. S.; Richter, R.; Crocker, D. E.; Fustukjian, A.; Hunter, M. E.; Rea, L. D.; Furlong, C. E.; Meyer, W. K.; Clark, N. L.
10.1101/2022.09.29.510191 — evolutionary biology — Posted on 2023-04-20
1390 A major 6 Mb superlocus is involved in pyrethroid resistance in the common bed bug Cimex lectularius
Haberkorn, C.; David, J.-P.; Henri, H.; Delpuech, J.-M.; Lasseur, R.; Vavre, F.; Varaldi, J.
10.1101/2023.01.06.522975 — evolutionary biology — Posted on 2023-04-20
1394 Zika viruses encode multiple upstream open reading frames in the 5' viral region with a role in neurotropism
Lefevre, C.; Cook, G. M.; Dinan, A. M.; Torii, S.; Stewart, H.; Gibbons, G.; Nicholson, A. S.; Echavarria-Consuegra, L.; Meredith, L. W.; Lulla, V.; Kenyon, J. C.; Goodfellow, I. G.; Deane, J. E.; Graham, S. C.; Lakatos, A.; Lambrechts, L.; Brierley, I.; Irigoyen, N.
10.1101/112904 — microbiology — Posted on 2023-04-20
1395 Combined inhibition of homologous PTPN1 and PTPN2 is synergistic in enhancing CD8 T cell effector functions.
Perez-Quintero, L. A.; Martinez-Cordoba, Z.; Carli, C.; Poirier, A.; Kamyabiazar, S.; Feng, C.-H.; Pacis, A.; Zolotarov, Y.; Pike, K.-A.; Delisle, J.-S.; Tremblay, M. L.
10.1101/2023.04.17.537264 — immunology — Posted on 2023-04-20
1396 Emotional Vocalizations Alter Behaviors and Neurochemical Release into the Amygdala
Ghasemahmad, Z.; Mrvelj, A.; Panditi, R.; Sharma, B.; Perumal, K. D.; Wenstrup, J. J.
10.1101/2022.07.02.498564 — neuroscience — Posted on 2023-04-20
1398 Reactive Inhibitory Control Precedes Stuttering Events
Orpella, J.; Flick, G.; Assaneo, F.; Pylkkanen, L.; Poeppel, D.; Jackson, E. S.
10.1101/2022.08.02.501857 — neuroscience — Posted on 2023-04-20
1399 Reliability of resting-state functional connectivity in the human spinal cord: assessing the impact of distinct noise sources
Kaptan, M.; Horn, U.; Vannesjo, S. J.; Mildner, T.; Weiskopf, N.; Finsterbusch, J.; Brooks, J. C.; Eippert, F.
10.1101/2022.12.23.521768 — neuroscience — Posted on 2023-04-20
1403 TOR coordinates Cytokinin and Gibberellin signals mediating development and defense
Marash, I.; Gupta, R.; Anand, G.; Leibman-Markus, M.; Lindner, N.; Israeli, A.; Nir, D.; Avni, A.; Bar, M.
10.1101/2022.03.07.483332 — plant biology — Posted on 2023-04-20
1404 A community driven GWAS summary statistics standard
Hayhurst, J.; Buniello, A.; Harris, L.; Mosaku, A.; Chang, C.; Gignoux, C. R.; Hatzikotoulas, K.; Karim, M. A.; Lambert, S. A.; Lyon, M.; McMahon, A.; Okada, Y.; Pirastu, N.; Rayner, N. W.; Schwartzentruber, J.; Vaughan, R.; Verma, S.; Wilder, S. P.; Cunningham, F.; Hindorff, L.; Wiley, K.; Parkinson, H.; Barroso, I.
10.1101/2022.07.15.500230 — bioinformatics — Posted on 2023-04-20
1411 A robust and flexible deep-learning workflow for animal tracking
Dutta, A.; Perez-Campanero, N.; Taylor, G. K.; Zisserman, A.; Newport, C.
10.1101/2023.04.20.537633 — animal behavior and cognition — Posted on 2023-04-20
1414 Actin polymerization drives lumen formation in a human epiblast model
Indana, D.; Zakharov, A.; Lim, Y.; Dunn, A. R.; Bhutani, N.; Shenoy, V.; Chaudhuri, O.
10.1101/2023.04.20.537711 — developmental biology — Posted on 2023-04-20
1416 Influence of Alzheimer's disease related neuropathology on local microenvironment gene expression in the human inferior temporal cortex
Kwon, S. H.; Parthiban, S.; Tippani, M.; Divecha, H. R.; Eagles, N. J.; Lobana, J. S.; Williams, S. R.; Mark, M.; Bharadwaj, R. A.; Kleinman, J. E.; Hyde, T. M.; Page, S. C.; Hicks, S. C.; Martinowich, K.; Maynard, K. R.; Collado-Torres, L.
10.1101/2023.04.20.537710 — neuroscience — Posted on 2023-04-20
1419 Design of effective personalised perturbation strategies for enhancing cognitive intervention in Alzheimer's disease
Vohryzek, J.; Cabral, J.; Perl, Y. S.; Demirtas, M.; Falcon, C.; Gispert, D.; Bosch, B.; Balasa, M.; Kringelbach, M. L.; Sanchez, R.; Ruffini, G.; Deco, G.
10.1101/2023.04.20.537688 — neuroscience — Posted on 2023-04-20
1421 Contrasting walking styles map to discrete neural substrates in the mouse brainstem
Worley, A.; Kirby, A.; Luks, S.; Samardzic, T.; Ellison, B.; Broom, L.; Latremoliere, A.; VanderHorst, V. g.
10.1101/2023.04.19.537568 — neuroscience — Posted on 2023-04-20
1422 Cooperation and deception through stigmergic interactions in human groups
Bassanetti, T.; Cezera, S.; Delacroix, M.; Escobedo, R.; Blanchet, A.; Sire, C.; Theraulaz, G.
10.1101/2023.04.20.537511 — animal behavior and cognition — Posted on 2023-04-20
1425 RhoA GEF Mcf2lb regulates rosette integrity during collective cell migration
Olson, H. M.; Maxfield, A.; Calistri, N. L.; Heiser, L. M.; Nechiporuk, A. V.
10.1101/2023.04.19.537573 — developmental biology — Posted on 2023-04-20
1426 Increased activity of IRE1 improves the clinical presentation of EAE
Bracchi-Ricard, V.; Nguyen, K.; Ricci, D.; Gaudette, B.; Henao-Meija, J.; Brambilla, R.; Martynyuk, T.; Gidalevitz, T.; Allman, D.; Bethea, J. R.; Argon, Y.
10.1101/2023.04.19.537391 — neuroscience — Posted on 2023-04-20
1428 Electrophysiological correlates of attention in the locus coeruleus - anterior cingulate cortex circuit during the rodent continuous performance test
Hallock, H. L.; Adiraju, S.; Miranda-Barrientos, J.; McInerney, J. M.; Oh, S.; DeBrosse, A. C.; Li, Y.; Carr, G.; Martinowich, K.
10.1101/2023.04.19.537406 — neuroscience — Posted on 2023-04-20
1431 Persistently increased post-stress activity of paraventricular thalamic neurons is essential for the emergence of stress-induced maladaptive behavior
Jasz, A.; Biro, L.; Buday, Z.; Kiraly, B.; Szalardy, O.; Horvath, K.; Komlosi, G.; Bodizs, R.; Kovacs, K. J.; Diana, M. A.; Hangya, B.; Acsady, L.
10.1101/2023.04.20.537629 — neuroscience — Posted on 2023-04-20
1433 Early-life stress exposure impacts the hippocampal synaptic proteome in a mouse model of Alzheimer's disease: age- and pathology-dependent effects on mitochondrial proteins
Kotah, J. M.; Kater, M. S. J.; Hoeijmakers, L.; Brosens, N.; Lesuis, S.; Tandari, R.; Marchetto, L.; Yusaf, E.; Smit, A.; Lucassen, P.; Krugers, H.; Verheijen, M.; Korosi, A.
10.1101/2023.04.20.537660 — neuroscience — Posted on 2023-04-20
1436 Changes to Astrocyte-associated Protein Expression at Different Timepoints of Cuprizone Treatment
Frankle, L.; Riley, A.; Tomor, R.; Lee, H.; Jarzembak, K.; Benedict, O.; Sternbach, S.; Shelestak, J.; McDonough, J.; Clements, R.
10.1101/2023.04.20.537627 — neuroscience — Posted on 2023-04-20
1439 Mobilisation and analyses of publicly available SARS-CoV-2 data for pandemic responses
Rahman, N.; O'Cathail, C.; Zyoud, A.; Sokolov, A.; Oude Munnink, B.; Grüning, B. A.; Cummins, C.; Amid, C.; Nieuwenhuijse, D. F.; Visontai, D.; Yuan, D. Y.; Gupta, D.; Prasad, D.; Gulyas, G. M.; Rinck, G.; McKinnon, J.; Knaggs, J.; Skiby, J. E.; Steger, J.; Szarvas, J.; Gueye, K.; Papp, K.; Hoek, M.; Kumar, M.; Ventouratou, M. A.; Bouquieaux, M.-C.; Koliba, M.; Mansurova, M.; Haseeb, M.; Worp, N.; Harrison, P. W.; Leinonen, R.; Thorne, R.; Selvakumar, S.; Hunt, S.; Venkataraman, S.; Jayathilaka, S.; Cezard, T.; Maier, W.; Waheed, Z.; Iqbal, Z.; Aarestrup, F. M.; Csabai, I.; Koopmans, M.; Burd
10.1101/2023.04.19.537514 — bioinformatics — Posted on 2023-04-20
1440 Contigs directed gene annotation (ConDiGA) for accurate protein sequence database construction in metaproteomics
Wu, E.; Mallawaarachchi, V.; Zhao, J.; Yang, Y.; Liu, H.; Wang, X.; Shen, C.; Lin, Y.; Qiao, L.
10.1101/2023.04.19.537311 — bioinformatics — Posted on 2023-04-20
1441 Machine learning detection of SARS-CoV-2 high-risk variants
Li, L.; Li, C.; Li, N.; Zou, D.; Zhao, W.; Xue, Y.; Zhang, Z.; Bao, Y.; Song, S.
10.1101/2023.04.19.537460 — bioinformatics — Posted on 2023-04-20
1442 An autoinhibited state of 53BP1 revealed by chemical probes and protein engineering
Cui, G.; Botuyan, M. V.; Drane, P.; Hu, Q.; Bragantini, B.; Thompson, J. R.; Schuller, D. J.; Perfetti, M. T.; James, L. I.; Frye, S. V.; Chowdhury, D.; Mer, G.
10.1101/2023.04.20.534960 — biochemistry — Posted on 2023-04-20
1443 Alternative mRNA splicing controls the functions of the histone H3K27 demethylase UTX/KDM6A
Fotouhi, O.; Nizamuddin, S.; Schilling, O.; Knuechel-Clarke, R.; Manke, T.; Biniossek, M. L.; Timmers, H. T. M.; Falk, S.
10.1101/2023.04.20.536794 — biochemistry — Posted on 2023-04-20
1445 Conserved enhancer logic controls the notochord expression of vertebrate Brachyury
Kemmler, C. L.; Smolikova, J.; Moran, H. R.; Mannion, B. J.; Knapp, D.; Lim, F.; Czarkwiani, A.; Hermosilla Aguayo, V.; Rapp, V.; Fitch, O. E.; Boetschi, S.; Selleri, L.; Farley, E.; Braasch, I.; Yun, M.; Visel, A.; Osterwalder, M.; Mosimann, C.; Kozmik, Z.; Burger, A.
10.1101/2023.04.20.536761 — genetics — Posted on 2023-04-20
1446 TAR Syndrome-associated Rbm8a deficiency causes hematopoietic defects and attenuates Wnt/PCP signaling
Kocere, A.; Chiavacci, E.; Mendez-Acevedo, K. M.; Soneson, C.; Hiltabidle, M. S.; Raghunath, A.; MacGowan, J. S.; Shavit, J. A.; Panakova, D.; Williams, M. L. K.; Robinson, M. D.; Mosimann, C.; Burger, A.
10.1101/2023.04.12.536513 — developmental biology — Posted on 2023-04-20
1448 Dietary environmental factors shape the immune defence against infection with Cryptosporidium
Maradana, M. R.; Marzook, N. B.; Diaz Perez, O.; Mkandawire, T.; Diny, N. L.; Li, Y.; Liebert, A.; Shah, K.; Tolaini, M.; Kvac, M.; Stockinger, B.; Sateriale, A.
10.1101/2023.03.30.534739 — immunology — Posted on 2023-04-20
1450 Pharmacologically targeting KRASG12D in PDAC models:tumor cell intrinsic and extrinsic impact
Kumarasamy, V.; Frangou, C.; Wang, J.; Wan, Y.; Dynka, A.; Rosenheck, H.; Dey, P.; Abel, E. V.; Knudsen, E.; Witkiewicz, A.
10.1101/2023.03.18.533261 — cancer biology — Posted on 2023-04-20
1455 Longitudinal Survey of Astrovirus infection in different bat species in Zimbabwe: Evidence of high genetic Astrovirus diversity
Chidoti, V.; De Nys, H.; Abdi, M.; Mashura, G.; Pinarello, V.; Chiweshe, N.; Matope, G.; Guerrini, L.; Pfulenyi, D.; Cappelle, J.; Mwandiringana, E.; Misse, D.; Elizabeth, G.; Bourgarel, M.; Liegeois, F.
10.1101/2023.04.14.536987 — molecular biology — Posted on 2023-04-20
1456 Evidence accumulation rate moderates the relationship between enriched environment exposure and age-related response speed declines.
Brosnan, M. B.; O'Neill, M. H.; Loughnane, G. M.; Pearce, D. J.; Fleming, B.; Zhou, S. H.; Chong, T. T. J.; Nobre, A. C.; O'Connell, R. G.; Bellgrove, M. A.
10.1101/2021.10.28.466233 — neuroscience — Posted on 2023-04-20
1457 Engineering genetic circuits in receiver cells for diffusion-based molecular data communications
Durmaz, M. G.; Tulluk, N.; Aksoy, R. D.; Yilmaz, H. B.; Yang, B.; Wipat, A.; Pusane, A. E.; Mısırlı, G.; Tugcu, T.
10.1101/2023.04.18.536609 — synthetic biology — Posted on 2023-04-20
1458 Incorporating environmental heterogeneity and observation effort to predict host distribution and viral spillover from a bat reservoir.
Ribeiro, R.; Matthiopoulos, J.; Lindgren, F.; Tello, C.; Zariquiey, C. M.; Valderrama, W.; Rocke, T. E.; Streicker, D. G.
10.1101/2023.04.04.535562 — ecology — Posted on 2023-04-20
1461 BayFlux: A Bayesian method to quantify metabolic Fluxes and their uncertainty at the genome scale
Backman, T. W. H.; Schenk, C.; Radivojevic, T.; Ando, D.; Singh, J.; Czajka, J. J.; Costello, Z.; Keasling, J. D.; Tang, Y.; Akhmatskaya, E.; Garcia Martin, H.
10.1101/2023.04.19.537435 — systems biology — Posted on 2023-04-20
1467 Grubraw, a chemogenetic generator of mitochondrial pyruvate, reveals new mechanisms of mitochondrial metabolic control that underlie the Warburg effect
Potekhina, E. S.; Bass, D. Y.; Ivanenko, A. V.; Moshchenko, A. A.; Korzhenevskiy, D. A.; Karnaeva, A. E.; Zakirova, N. F.; Ivanov, A. V.; Shimolina, L. E.; Shirmanova, M. V.; Lyang, O. V.; Patsap, O. I.; Bogeski, I.; Nesterenko, A. M.; Belousov, V.
10.1101/2023.04.18.537329 — cancer biology — Posted on 2023-04-20
1468 Predicting neoadjuvant treatment response in triple-negative breast cancer using machine learning
Bhattarai, S.; Saini, G.; Li, H.; Duanmu, H.; Seth, G.; Fisher, T. B.; Janssen, E. A. M.; Kiraz, U.; Kong, J.; Aneja, R.
10.1101/2023.04.17.536459 — cancer biology — Posted on 2023-04-20
1469 In vivo metabolomics identifies CD38 as an emergent vulnerability in LKB1-mutant lung cancer
Deng, J.; Peng, D. H.; Fenyo, D.; Hao, Y.; Lopez, A.; Levin, D.; Meynardie, M.; Quinteros, M.; Ranieri, M.; Sahu, S.; Lau, S.; Shum, E.; Velcheti, V.; Punekar, S. R.; Rekhtman, N.; Dowling, C. M.; Weerasekara, V.; Xue, Y.; Ji, h.; Siu, Y.; Johns, D.; Hata, A.; Shimamura, T.; Poirier, J.; Rudin, C. M.; Hattori, T.; Koide, S.; Papagiannakopoulos, T.; Neel, B.; Bardeesy, N.; Wong, K.-K.
10.1101/2023.04.18.537350 — cancer biology — Posted on 2023-04-20
1471 Intermediate antiparallel beta structure in amyloid plaques revealed by infrared spectroscopic imaging
Holcombe, B.; Foes, A.; Banerjee, S.; Yeh, K.; Wang, S.-H. J.; Bhargava, R.; Ghosh, A.
10.1101/2023.04.18.537414 — biophysics — Posted on 2023-04-20
1474 Exhaustive benchmarking of de novo assembly methods for eukaryotic genomes
Southwood, D.; Rane, R. V.; Lee, S. F.; Oakeshott, J. G.; Ranganathan, S.
10.1101/2023.04.18.537422 — bioinformatics — Posted on 2023-04-20
1478 A Comprehensive Benchmark Study on Biomedical Text Generation and Mining with ChatGPT
Chen, Q.; Sun, H.; Liu, H.; Jiang, Y.; Ran, T.; Jin, X.; Xiao, X.; Lin, Z.; Niu, Z.; Chen, H.
10.1101/2023.04.19.537463 — bioinformatics — Posted on 2023-04-20
1481 Targeting Sex Determination to Suppress Mosquito Populations
Li, M.; Kandul, N. P.; Sun, R.; Yang, T.; Benetta, E. D.; Brogan, D. J.; Antoshechkin, I.; Sanchez C., H. M.; Zhan, Y.; DeBeaubien, N. A.; Loh, Y. M.; Su, M. P.; Montell, C.; Marshall, J. M.; Akbari, O. S.
10.1101/2023.04.18.537404 — bioengineering — Posted on 2023-04-20
1484 Cell state-dependent chromatin targeting in NUT carcinoma
Kuroda, M. I.; Alekseyenko, A. A.; Zee, B. M.; Dhoondia, Z.; Kang, H.; Makofske, J. L.
10.1101/2023.04.18.537367 — genomics — Posted on 2023-04-20
1489 Exploring the impact of read clustering thresholds on RADseq-based systematics: an empirical example from European amphibians.
Rancilhac, L.; Sylvestre, F.; Hutter, C. R.; Arntzen, J. W.; Babik, W.; Crochet, P.-A.; Deso, G.; Duguet, R.; Galan, P.; Pabijan, M.; Policain, M.; Priol, P.; Sabino-Pinto, J.; Capstick, M.; Elmer, K. R.; Dufresnes, C.; Vences, M.
10.1101/2023.04.19.537466 — evolutionary biology — Posted on 2023-04-20
1491 Evolution of ancient satellite DNAs in extant alligators and caimans (Crocodylia, Reptilia)
Sales-Oliveira, V. C.; dos Santos, R. Z.; Goes, C. A. G.; Calegari, R. M.; Garrido-Ramos, M. A.; Altmanova, M.; Ezaz, T.; Liehr, T.; Porto-Foresti, F.; Utsunomia, R.; Cioffi, M. B.
10.1101/2023.04.18.537305 — evolutionary biology — Posted on 2023-04-20
1492 Purifying Selection and Persistent Polymorphism among Nuclei in the Multinucleate Arbuscular Mycorrhizal (AM) Fungi
Manyara, D.; Sanchez-Garcia, M.; Thoren, M. H.; Montoliu-Nerin, M.; Cheng, G.; Bever, J. D.; Johannesson, H.; Rosling, A.
10.1101/2023.04.18.537338 — evolutionary biology — Posted on 2023-04-20
1494 Molecular physiology of Antarctic diatom natural assemblages reveals multiple strategies contributing to their ecological success
Moreno, C. M.; Bernish, M.; Meyer, M. G.; Li, Z.; Waite, N.; Cohen, N. R.; Schofield, O.; Marchetti, A.
10.1101/2023.04.19.537459 — ecology — Posted on 2023-04-20
1495 The distribution, phenology, host range and pathogen prevalence of Ixodes ricinus in France: a systematic map and narrative review
Perez, G.; Bournez, L.; Boulanger, N.; Fite, J.; Livoreil, B.; McCoy, K. D.; Quillery, E.; Rene-Martellet, M.; Bonnet, S. I.
10.1101/2023.04.18.537315 — ecology — Posted on 2023-04-20
1496 The Sterile Insect Technique can efficiently reduce the reproduction of the spotted wing drosophila (Drosophila suzukii) in strawberry
Gard, B.; Panel, A.; Labbetoul, A.; Bosshard, N.; Xuereb, A.; Cariou, B.; Debelle, A.; Oliva, C.; Fellous, S.
10.1101/2023.04.18.537326 — ecology — Posted on 2023-04-20
1497 Monocyte-derived Dll4 is a novel contributor to persistent systemic inflammation in HIV patients
Wang, S.; Singh, M. V.; Yang, H.; Morrell, C. N.; Awad Mohamad, L.; Xu, J. J.; Nguyen, T. T.; Ture, S. K.; Tyrell, A.; Maggirwar, S. B.; Schifitto, G.; Pang, J.
10.1101/2023.04.18.537330 — molecular biology — Posted on 2023-04-20
1499 Dietary fibers benefits on glucose homeostasis require type 2 conventional dendritic cells in mice fed a high-fat diet
Gelineau, A.; Marcelin, G.; Ouhachi, M.; Dussaud, S.; Voland, L.; Baba, I.; Rouault, C.; Yvan-Charvet, L.; Clement, K.; Tussiwand, R.; Huby, T.; Gautier, E. L.
10.1101/2023.04.19.537402 — immunology — Posted on 2023-04-20
1504 GABA, glucose and insulin orchestrate CD4+ T cells effector functions
Jin, Z.; Hammoud, H.; Bhandage, A. K.; Korol, S. V.; Trujeque-Ramos, O.; Koreli, S.; Chowdhury, A. I.; Sandbaumhuter, F. A.; Jansson, E.; Bergstein, P.; Andren, P.; Kamali-Moghaddam, M.; Birnir, B.
10.1101/2023.04.18.537327 — physiology — Posted on 2023-04-20
1506 Pyro: A Comprehensive Pipeline for Eukaryotic Genome Assembly
Southwood, D.; Rane, R. V.; Lee, S. F.; Oakeshott, J. G.; Ranganathan, S.
10.1101/2023.04.18.537425 — bioinformatics — Posted on 2023-04-20
1508 C-di-AMP levels modulate Staphylococcus aureus cell wall thickness as well as virulence and contribute to antibiotic resistance and tolerance
Dengler Haunreiter, V.; Tarnutzer, A.; Baer, J.; von Matt, M.; Hertegonne, S.; Andreoni, F.; Vulin, C.; Künzi, L.; Menzi, C.; Kiefer, P.; Christen, P.; Vorholt, J. A.; Zinkernagel, A. S.
10.1101/2023.04.18.537236 — microbiology — Posted on 2023-04-20
1510 Loss of myeloid cannabinoid CB1 receptor confers atheroprotection by reducing macrophage proliferation and immunometabolic reprogramming
Wang, Y.; Li, G.; Chen, B.; Shakir, G.; Volz, M.; van der Vorst, E.; Maas, S.; Muley, C.; Bartelt, A.; Li, Z.; Sachs, N.; Maegdefessel, L.; Nazari Jahantigh, M.; Hristov, M.; Lacy, M.; Lutz, B.; Weber, C.; Herzig, S.; Guillamat Prats, R.; Steffens, S.
10.1101/2023.04.06.535832 — immunology — Posted on 2023-04-20
1511 Enhanced survival and low proliferation marks multifunctional virus specific memory CD4 T cells
Westerhof, L. M.; Noonan, J.; Hargrave, K. E.; Chimbayo, E. T.; Cheng, Z.; Purnell, T.; Jackson, M. R.; Borcherding, N.; MacLeod, M. K.
10.1101/2022.12.13.520219 — immunology — Posted on 2023-04-20
1512 Modular, cement-free, customized headpost and connector-chamber implants for macaques
Psarou, E.; Vezoli, J.; Schölvinck, M. L.; Ferracci, P.-A.; Zhang, Y.; Grothe, I.; Roese, R.; Fries, P.
10.1101/2022.11.09.515849 — neuroscience — Posted on 2023-04-20
1513 Cardiac gene therapy with PDE2A limits remodeling and arrhythmias in mouse models of heart failure induced by catecholamines
Kamel, R.; Bourcier, A.; Margaria, J. P.; Varin, A.; Hivonnait, A.; Mercier-Nome, F.; Mika, D.; Ghigo, A.; Charpentier, F.; Algalarrondo, V.; Hirsch, E.; Fischmeister, R.; Vandecasteele, G.; Leroy, J.
10.1101/2023.04.17.537274 — physiology — Posted on 2023-04-20
1514 Biased activation of the receptor tyrosine kinase HER2
Catapano, C.; Rahm, J. V.; Omer, M.; Teodori, L.; Kjems, J.; Dietz, M. S.; Heilemann, M.
10.1101/2022.12.04.519064 — biophysics — Posted on 2023-04-20
1518 Symmetry breaking organizes the brain's resting state manifold
Fousek, J.; Rabuffo, G.; Gudibanda, K.; Sheheitli, H.; Jirsa, V.; Petkoski, S.
10.1101/2022.01.03.474841 — neuroscience — Posted on 2023-04-20
1520 Surface-guided computing to analyze subcellular morphology and membrane-associated signals in 3D
Zhou, F. Y.; Weems, A.; Gihana, G. M.; Chen, B.; Chang, B.-J.; Driscoll, M.; Danuser, G.
10.1101/2023.04.12.536640 — bioinformatics — Posted on 2023-04-20
1526 Dextromethorphan inhibits collagen transport in the endoplasmic reticulum eliciting an anti-fibrotic response in ex-vivo and in vitro models of pulmonary fibrosis
Khan, M. M.; Zukowska, J.; Jung, J.; Galea, G.; Tuechler, N.; Halavatyi, A.; Tischer, C.; Haberkant, P.; Stein, F.; Jung, F.; Landry, J.; Khan, A. M.; Oorschot, V.; Becher, I.; Neumann, B.; Muley, T.; Winter, H.; Duerr, J.; Mall, M.; Savitski, M.; Pepperkok, R.
10.1101/2023.04.19.537530 — cell biology — Posted on 2023-04-19
1528 Partitioning to ordered membrane domains regulates the kinetics of secretory traffic
Castello-Serrano, I.; Heberle, F. A.; Diaz-Rohrer, B.; Ippolito, R.; Shurer, C. R.; Lujan, P.; Campelo, F.; Levental, K. R.; Levental, I.
10.1101/2023.04.18.537395 — cell biology — Posted on 2023-04-19
1529 Design principles of Cdr2 node patterns in fission yeast cells
Opalko, H. E.; Geng, S.; Hall, A. R.; Vavylonis, D.; Moseley, J. B.
10.1101/2023.04.19.537536 — cell biology — Posted on 2023-04-19
1534 Pharmacological inhibition of CLK2 activates YAP by promoting alternative splicing of AMOTL2
Bulos, M. L.; Grzelak, E. M.; Li-Ma, C.; Chen, E.; Hull, M.; Johnson, K. A.; Bollong, M. J.
10.1101/2023.04.19.537449 — cell biology — Posted on 2023-04-19
1537 Development and calibration of the FSPM CPlantBox to represent the interactions between water and carbon fluxes in the soil-plant-atmosphere continuum
Giraud, M.; Le Gall, S.; Harings, M.; Javaux, M.; Leitner, D.; Meunier, F.; Rothfuss, Y.; van Dusschoten, D.; Vanderborght, J.; Vereecken, H.; Lobet, G.; Schnepf, A.
10.1101/2023.04.18.537289 — plant biology — Posted on 2023-04-19
1538 Selection on visual opsin genes in diurnal Neotropical frogs and loss of the SWS2 opsin in poison frogs
Wan, Y. C.; Navarrete, M. J.; O'Connell, L. A.; Uricchio, L. H.; Roland, A. B.; Maan, M. E.; Ron, S. R.; Betancourth-Cundar, M.; Pie, M. R.; Howell, K. A.; Richards-Zawacki, C. L.; Cummings, M. E.; Cannatella, D. C.; Santos, J. C.; Tarvin, R. D.
10.1101/2022.10.18.510514 — evolutionary biology — Posted on 2023-04-19
1539 Deficiency of macrophage-derived Dnase1L3 causes lupus-like phenotypes in mice
Engavale, M.; Hernandez, C. J.; Infante, A.; LeRoith, T.; Radovan, E.; Evans, L.; Villarreal, J.; Reilly, C. M.; Sutton, R. B.; Keyel, P. A.
10.1101/2023.04.17.537232 — immunology — Posted on 2023-04-19
1540 CRISPR-Cas9 mediated endogenous utrophin upregulation improves Duchenne Muscular Dystrophy
Guiraud, S.; Dastidar, S.; Mazed, F.; Amor, F.; Ralu, M.; de Cian, A.; Richard, I.; Ronzitti, G.; Tedesco, F. S.; Amendola, M.
10.1101/2023.04.18.536394 — molecular biology — Posted on 2023-04-19
1541 Latent inter-organ mechanism of idiopathic pulmonary fibrosis unveiled by a generative computational approach
Kozawa, S.; Tejima, K.; Takagi, S.; Kuroda, M.; Nogami-Itoh, M.; Kitamura, H.; Niwa, T.; Ogura, T.; Natsume-Kitatani, Y.; Sato, T. N.
10.1101/2023.04.18.537146 — pathology — Posted on 2023-04-19
1542 Allosteric coupling asymmetry mediates paradoxical activation of BRAF
Rasmussen, D. M.; Semonis, M. M.; Muretta, J. M.; Thompson, A. R.; Thomas, D. D.; Pomerantz, W. C. K.; Levinson, N. M.
10.1101/2023.04.18.536450 — biophysics — Posted on 2023-04-19
1543 BrainTACO: An Explorable Multi-Scale Multi-Modal Brain Transcriptomic And Connectivity Data Resource
Ganglberger, F. J.; Toepfer, M.; Kargl, D.; Hernandez-Lallement, J.; Lawless, N.; Fernandez-Albert, F.; Haubensak, W.; Buehler, K.
10.1101/2023.04.18.537294 — bioinformatics — Posted on 2023-04-19
1546 A Multi-omic Analysis of the Human Lung Reveals Distinct Cell Specific Aging and Senescence Molecular Programs
De Man, R.; McDonough, J. E.; Adams, T. S.; Manning, E. P.; Myers, G.; Vos, R.; Ceulemans, L.; Dupont, L.; Vanaudenaerde, B. M.; Wuyts, W.; Rosas, I. O.; Hagood, J. S.; Ambalavanan, N.; Niklason, L.; Hansen, K. C.; Yan, X.; Kaminski, N.
10.1101/2023.04.19.536722 — genomics — Posted on 2023-04-19
1547 Hybridization and its impact on the ontogenetic allometry of skulls in macaques
Ito, T.; Kimura, R.; Wakamori, H.; Tanaka, M.; Tezuka, A.; Nagano, A. J.; Hamada, Y.; kawamoto, Y.
10.1101/2023.04.19.536293 — evolutionary biology — Posted on 2023-04-19
1548 THE OLFACTORY RECEPTOR Olfr78 REGULATES DIFFERENTIATION OF ENTEROCHROMAFFIN CELLS IN THE MOUSE COLON
Garcia, M.-I.; Dinsart, G.; Leprovots, M.; Lefort, A.; Libert, F.; Quesnel, Y.; Veiten, A.; Vassart, G.; Huysseune, S.; Parmentier, M.
10.1101/2023.04.19.536389 — cell biology — Posted on 2023-04-19
1549 Novel protein interaction network of human calcitonin receptor-like receptor revealed by label-free quantitative proteomics
Manolis, D.; Hasan, S.; Ettelaie, C.; Maraveyas, A.; O'Brien, D. P.; Kessler, B. M.; Kramer, H. B.; Nikitenko, L. L.
10.1101/2023.04.18.537143 — cell biology — Posted on 2023-04-19
1552 An ex vivo human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy
Zhang, X.; Pechous, R. D.; Malaviarachchi, P. A.; Banerjee, S. K.; Byrum, S.; Alkam, D.; Ghaffarieh, A.; Kurten, R. C.; Kennedy, J. L.
10.1101/2023.04.18.537373 — microbiology — Posted on 2023-04-19
1553 Resin acids play key roles in shaping microbial communities during degradation of spruce bark
Ristinmaa, A. S.; Tafur Rangel, A.; Idström, A.; Valenzuela, S.; Kerkhoven, E. J.; Pope, P.; Hasani, M.; Larsbrink, J.
10.1101/2023.04.19.537524 — microbiology — Posted on 2023-04-19
1556 Antivirals against monkeypox infections
Chiem, K.; Nogales, A.; Lorenzo, M. M.; Morales Vasquez, D.; Xiang, Y.; Gupta, Y.; Blasco, R.; de la Torre, J. C.; Martinez-Sobrido, L.
10.1101/2023.04.19.537483 — microbiology — Posted on 2023-04-19
1559 Complete Genome Sequences and Characteristics of Seven Novel Mycobacteriophages
Weiss, S. M.; Happy, K. K.; Baliraine, F. W.; Beach, A. K.; Brobston, S. M.; Martinez, C. P.; Menard, K. J.; Orton, S. M.; Salazar, A. L.; Frederick, G. D.; Baliraine, F. N.
10.1101/2023.04.18.537415 — microbiology — Posted on 2023-04-19
1561 Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents infection of Omicron lineages
Marcotte, H.; Cao, Y.; Zuo, F.; Simonelli, L.; Sammartino, J. C.; Pedotti, M.; Sun, R.; Cassaniti, I.; Hagbom, M.; Piralla, A.; Yang, J.; Du, L.; Percivalle, E.; Bertoglio, F.; Schubert, M.; Abolhassani, H.; Sherina, N.; Guerra, C.; Borte, S.; Razaei, N.; Kumagai-Braesch, M.; Xue, Y.; Gronwall, C.; Klareskog, L.; Calzolai, L.; Cavalli, A.; Wang, Q.; Robbiani, D. F.; Hust, M.; Shi, Z.; Feng, L.; Svensson, L.; Chen, L.; Bao, L.; Baldanti, F.; Qin, C.; Xiao, J.; Hammarstrom, L.; Yang, X. L.; Varani, L.; Sunney Xie, X.; Pan-Hammarstrom, Q.
10.1101/2023.04.17.536908 — microbiology — Posted on 2023-04-19
1564 Functional connectomics spanning multiple areas of mouse visual cortex
The MICrONs Consortium, ; Bae, J. A.; Baptiste, M.; Bishop, C. A.; Bodor, A. L.; Brittain, D.; Buchanan, J.; Bumbarger, D. J.; Castro, M. A.; Celii, B.; Cobos, E.; Collman, F.; da Costa, N. M.; Dorkenwald, S.; Elabbady, L.; Fahey, P. G.; Fliss, T.; Froudarakis, E.; Gager, J.; Gamlin, C.; Gray-Roncal, W. R.; Halageri, A.; Hebditch, J.; Jia, Z.; Jordan, C.; Joyce, E.; Joyce, J.; Kapner, D.; Kemnitz, N.; Kinn, S.; Kitchell, L. M.; Koolman, S.; Kuehner, K.; Lee, K.; Li, K.; Lu, R.; Macrina, T.; Mahalingam, G.; Matelsky, J.; McReynolds, S.; Miranda, E.; Mitchell, E.; Mondal, S. S.; Moore, M.; Mu,
10.1101/2021.07.28.454025 — neuroscience — Posted on 2023-04-19
1567 Generalization of contextual fear is sex-specifically affected by high salt intake
Beaver, J. N.; Weber, B. L.; Ford, M. T.; Anello, A. E.; Ruffin, K. M.; Kassis, S. K.; Gilman, L.
10.1101/2022.09.20.508397 — neuroscience — Posted on 2023-04-19
1568 Changes in brain metabolite levels across childhood
Perdue, M. V.; DeMayo, M. M.; Bell, T.; Boudes, E.; Bagshawe, M.; Harris, A. D.; Lebel, C.
10.1101/2022.11.30.518618 — neuroscience — Posted on 2023-04-19
1571 Long-term evolution of proliferating cells using the eVOLVER platform
Garcia-Ruano, D.; Jain, A.; Heins, Z. J.; Wong, B. G.; Wolle, E. Y.; Khalil, A. S.; Coudreuse, D.
10.1101/2023.03.28.534552 — evolutionary biology — Posted on 2023-04-19
1575 5-ASA can functionally replace Clostridia to prevent a post-antibiotic bloom of Candida albicans by maintaining epithelial hypoxia
Savage, H. P.; Bays, D. J.; Gonzalez, M. A. F.; Bejarano, E. J.; Nguyen, H.; Masson, H. L. P.; Carvalho, T. P.; Santos, R. L.; Thompson, G.; Bäumler, A. J.
10.1101/2023.04.17.537218 — microbiology — Posted on 2023-04-19
1576 Metagenome-derived virus-microbe ratios across ecosystems
Lopez-Garcia, P.; Gutierrez-Preciado, A.; Krupovic, M.; Ciobanu, M.; Deschamps, P.; Jardillier, L.; Lopez-Perez, M.; Rodriguez-Valera, F.; Moreira, D.
10.1101/2021.02.17.431581 — microbiology — Posted on 2023-04-19
1577 The representational geometry of cognitive maps under dynamic cognitive control
Park, S. A.; Zolfaghar, M.; Russin, J.; Miller, D. S.; O'Reilly, R. C.; Boorman, E. D.
10.1101/2023.02.04.527142 — neuroscience — Posted on 2023-04-19
1582 Fetal manipulation of maternal metabolism is a critical function of Igf2 imprinting
Lopez-Tello, J.; Yong, H. E.; Sandovici, I.; Christoforou, E. R.; Salazar-Petres, E.; Boyland, R.; Napso, T.; Constancia, M.; Sferruzzi-Perri, A. N.
10.1101/2023.04.19.537510 — developmental biology — Posted on 2023-04-19
1583 Derivation of trophoblast stem cells unveils unrestrained potential of mouse ESCs and epiblast
Jana, D.; Sailasree, P.; Singh, P.; Srivastava, M.; Vishnu, V. V.; Kale, H. T.; Lakshmi, B. J.; Srinivas, G.; Sowpati, D. T.; Shekar, P. C.
10.1101/2023.04.19.537518 — developmental biology — Posted on 2023-04-19
1589 The influence of axonal beading and undulation on axonal diameter mapping
Lee, H.-H.; Tian, Q.; Sheft, M.; Coronado-Leija, R.; Ramos Llorden, G.; Abdollahzadeh, A.; Fieremans, E.; Novikov, D. S.; Huang, S. Y.
10.1101/2023.04.19.537494 — neuroscience — Posted on 2023-04-19
1591 Does ipsilateral remapping following hand loss impact motor control of the intact hand?
Tucciarelli, R.; Ejaz, N.; Wesselink, D. B.; Kolli, V.; Hodgetts, C. J.; Diedrichsen, J.; Makin, T.
10.1101/2023.04.19.537443 — neuroscience — Posted on 2023-04-19
1592 Magnetic actuation of otoliths allows behavioral and brain-wide neuronal exploration of vestibulo-motor processing in larval zebrafish.
Beiza-Canelo, N.; Moulle, H.; Pujol, T.; Panier, T.; Migault, G.; Le Goc, G.; Tapie, P.; Desprat, N.; Straka, H.; Debregeas, G.; Bormuth, V.
10.1101/2023.04.18.537408 — neuroscience — Posted on 2023-04-19
1596 Radical fringe facilitates NOTCH1 and JAG1 cis interactions to sustain Hematopoietic stem cell fate
Thambyrajah, R.; Maqueda, M.; Neo, W. H.; Imbach, K. J.; Guillen, Y.; Grases, D.; Fadlullah, Z.; Gambera, S.; Matteini, F.; Wang, X.; Calero-Nieto, F. J.; Esteller, M.; Florian, M. C.; Porta, E.; Benedito, R.; Gottgens, B.; Lacaud, G.; Espinosa, L.; Bigas, A.
10.1101/2023.04.19.537430 — developmental biology — Posted on 2023-04-19
1597 Subchronic alteration of vestibular hair cells in mice: implications for multisensory gaze stabilization
Schenberg, L.; Palou, A.; Simon, F.; Bonnard, T.; Barton, C.-E.; Fricker, D.; Tagliabue, M.; Llorens, J.; Beraneck, M.
10.1101/2023.04.19.535725 — neuroscience — Posted on 2023-04-19
1599 A reproducible benchmark of resting-state fMRI denoising strategies using fMRIPrep and Nilearn
Wang, H.-T.; Meisler, S. L.; Sharmarke, H.; Clarke, N.; Gensollen, N.; Markiewicz, C. J.; Paugam, F.; Thirion, B.; Bellec, P.
10.1101/2023.04.18.537240 — neuroscience — Posted on 2023-04-19
1601 D-Serine agonism of GluN1-GluN3 NMDA receptors regulates the activity of enteric neurons and coordinates gut motility
Osorio, N.; Martineau, M.; Fortea, M.; Rouget, C.; Penalba, V.; Lee, C. J.; Boesmans, W.; Rolli-Derkinderen, M.; Patel, A. V.; Mondielli, G.; Conrod, S.; Labat-Gest, V.; Papin, A.; Sasabe, J.; Sweedler, J. V.; Vanden Berghe, P.; Delmas, P.; MOTHET, J.-P.
10.1101/2023.04.19.537136 — neuroscience — Posted on 2023-04-19
1602 How can graph theory inform the dual-stream model of speech processing? a resting-state fMRI study of post-stroke aphasia
Zhu, H.; Fitzhugh, M. C.; Keator, L. M.; Johnson, L.; Rorden, C.; Bonilha, L.; Fridriksson, J.; Rogalsky, C.
10.1101/2023.04.17.537216 — neuroscience — Posted on 2023-04-19
1605 A parabrachial-hypothalamic parallel circuit governs cold defense in mice
Yang, W. Z.; Xie, H.; Du, X.; Zhou, Q.; Xiao, Y.; Zhao, Z.; Jia, X.; Xu, J.; Zhang, W.; Li, Z.; Fu, X.; Hua, R.; Cai, J.; Chang, S.; Sun, J.; Sun, H.; Shen, Q.; Xu, Q.; Ni, X.; Tu, H.; Zheng, R.; Xu, X.; Wang, H.; Fu, Y.; Wang, L.; Li, X.; Yang, H.; Yao, Q.; Shen, W. L.
10.1101/2023.04.19.537288 — neuroscience — Posted on 2023-04-19
1607 Neural Extracellular Matrix Remodeling Signatures in Genetic and Acquired Mouse Models of Epilepsy
Blondiaux, A.; Jia, S.; Annamneedi, A.; Caliskan, G.; Schulze, J.; Montenegro-Venegas, C.; Wykes, R. C.; Fejtova, A.; Walker, M.; Stork, O.; Gundelfinger, E. D.; Dityatev, A.; Seidenbecher, C. I.
10.1101/2023.04.19.537468 — neuroscience — Posted on 2023-04-19
1609 Auditory hemispheric asymmetry as a specialization for actions and objects
Robert, P.; Zatorre, R.; Gupta, A.; Sein, J.; Anton, J.-L.; Belin, P.; Thoret, E.; Morillon, B.
10.1101/2023.04.19.537361 — neuroscience — Posted on 2023-04-19
1611 LeishMANIAdb: a comparative resource for Leishmania proteins
Tusnady, G. E.; Zeke, A.; Kalman, Z. E.; Fatoux, M.; Ricard-Blum, S.; Gibson, T. J.; Dobson, L.
10.1101/2023.03.08.531706 — bioinformatics — Posted on 2023-04-19
1613 Trans regulation of an odorant binding protein by a proto-Y chromosome affects male courtship in house fly
Delclos, P. J.; Adhikari, K.; Mai, A. B.; Hassan, O.; Oderhowho, A. A.; Sriskantharajah, V.; Trinh, T.; Meisel, R. P.
10.1101/2021.06.22.447776 — evolutionary biology — Posted on 2023-04-19
1615 Inner hair cell synapse density influences auditory processing
Ji, L.; Borges, B. C.; Martel, D. T.; Wu, C.; Liberman, M. C.; Shore, S. E.; Corfas, G.
10.1101/2022.05.02.490340 — neuroscience — Posted on 2023-04-19
1616 Combining fusion of cells with CRISPR-Cas9 editing for the cloning of large DNA fragments or complete bacterial genomes in yeast.
GUESDON, G.; GOURGUES, G.; RIDEAU, F.; IPOUTCHA, T.; MANSO-SILVAN, L.; JULES, M.; SIRAND-PUGNET, P.; BLANCHARD, A.; LARTIGUE, C.
10.1101/2023.03.14.531922 — synthetic biology — Posted on 2023-04-19
1617 Optimized path planning surpasses human efficiency in cryo-EM imaging
Li, Y.; Fan, Q.; Xu, Z.; Lee, E. R.; Cohn, J.; Demers, V.; Lee, J. Y.; Yip, L.; Cianfrocco, M. A.; Vos, S. M.
10.1101/2022.06.17.496614 — biophysics — Posted on 2023-04-19
1621 Timing of root barriers controls soil-to-shoot integration of rhizosphere status
Shen, D.; Wippel, K.; Remmel, S.; Zhang, P.; Kuertoes, N.; Neumann, U.; Kopriva, S.; Andersen, T. G.
10.1101/2023.04.19.537470 — plant biology — Posted on 2023-04-19
1624 AtMYB50 regulates root cell elongation by upregulating PECTIN METHYLESTERASE INHIBITOR 8 in Arabidopsis thaliana
Mase, K.; Mizuno, H.; Nakamichi, N.; Suzuki, T.; Kojima, T.; Kamiya, S.; Takeuchi, T.; Kondo, C.; Yamashita, H.; Sakaoka, S.; Morikami, A.; Tsukagoshi, H.
10.1101/2023.04.19.537493 — plant biology — Posted on 2023-04-19
1625 Efficient estimation of time-dependent functional connectivity using Structural Connectivity constraints
Hernandez, H.; Araya, D.; Gonzalez, L. L.; Roman, C.; Trujillo-Barreto, N.; Guevara, P.; El-Deredy, W.
10.1101/2022.09.21.508847 — bioinformatics — Posted on 2023-04-19
1626 FMRP regulates neuronal migration via MAP1B
Messaoudi, S.; Stoufflet, J.; Fouquet, C.; Doulazmi, M.; Allam, A.; Paillard, T.; Trembleau, A.; Caille, I.
10.1101/2023.03.06.530447 — neuroscience — Posted on 2023-04-19
1627 Development and calibration of the FSPM CPlantBox to represent the interactions between water and carbon fluxes in the soil-plant-atmosphere continuum
Giraud, M.; Le Gall, S.; Harings, M.; Javaux, M.; Leitner, D.; Meunier, F.; Rothfuss, Y.; van Dusschoten, D.; Vanderborght, J.; Vereecken, H.; Lobet, G.; Schnepf, A.
10.1101/2023.04.18.537289 — plant biology — Posted on 2023-04-19
1628 Deep imaging revealed dynamics and signaling in one-to-one pollen tube guidance
Mizuta, Y.; Sakakibara, D.; Nagahara, S.; Kaneshiro, I.; Nagae, T. T.; Kurihara, D.; Higashiyama, T.
10.1101/2023.04.19.537439 — plant biology — Posted on 2023-04-19
1629 Leukemic stem cells hijack lineage inappropriate signalling pathways to promote their growth
Kellaway, S. G.; Potluri, S.; Keane, P.; Blair, H.; Chin, P. S.; Ptasinska, A.; Worker, A.; Ames, L.; Adamo, A.; Coleman, D. J.; Khan, N.; Assi, S.; Krippner-Heidenreich, A.; Raghavan, M.; Cockerill, P. N.; Heidenreich, O.; Bonifer, C.
10.1101/2023.03.10.532081 — cancer biology — Posted on 2023-04-19
1630 Tamoxifen Response at Single Cell Resolution in Estrogen Receptor-Positive Primary Human Breast Tumors
Kim, H.; Whitman, A. A.; Wisniewska, K.; Kakati, R. T.; Garcia-Recio, S.; Calhoun, B. C.; Franco, H. L.; Perou, C. M.; Spanheimer, P. M.
10.1101/2023.04.01.535159 — cancer biology — Posted on 2023-04-19
1635 cAMP binding to closed pacemaker ion channels is cooperative
Kuschke, S.; Thon, S.; Schwabe, T.; Benndorf, K.; Schmauder, R.
10.1101/2023.04.18.537331 — biophysics — Posted on 2023-04-19
1636 Enhanced cell viscosity: a new phenotype associated withlamin A/C alterations
Jebane, C.; Varlet, A.-A.; Karnat, M.; Hernandez-Cedillo, L. M.; Lecchi, A.; Bedu, F.; Desgrouas, C.; Vigouroux, C.; Vantyghem, M.-C.; Viallat, A.; Rupprecht, J.-F.; Helfer, E.; Badens, C.
10.1101/2022.07.18.500411 — biophysics — Posted on 2023-04-19
1639 WNT activity reveals context-specific genetic effects on gene regulation in neural progenitors
Matoba, N.; Le, B. D.; Valone, J. M.; Wolter, J. M.; Mory, J.; Liang, D.; Aygun, N.; Broadaway, K. A.; Bond, M. L.; Mohlke, K. L.; Zylka, M. J.; Love, M. I.; Stein, J. L.
10.1101/2023.02.07.527357 — genetics — Posted on 2023-04-19
1640 Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants
de Melo, G. D.; Perraud, V.; Alvarez, F.; Vieites-Prado, A.; Kim, S.; Kergoat, L.; Coleon, A.; Trueb, B. S.; Tichit, M.; Piazza, A.; Thierry, A.; Hardy, D.; Wolff, N.; Munier, S.; Koszul, R.; Simon-Loriere, E.; Thiel, V.; Lecuit, M.; Lledo, P.-M.; Renier, N.; Larrous, F.; Bourhy, H.
10.1101/2022.08.31.505985 — neuroscience — Posted on 2023-04-19
1643 P2X7-dependent exchange of extracellular microparticles and mitochondria by mouse microglia
Falzoni, S.; Chiozzi, P.; Vultaggio-Poma, V.; Tarantini, M.; Adinolfi, E.; Boldrini, P.; Giuliani, A. L.; Gorecki, D. C.; Di Virgilio, F.
10.1101/2023.04.18.537325 — cell biology — Posted on 2023-04-19
1651 ApoE isoforms differentially regulate neuronal membrane proteasomes to shift the threshold for pathological aggregation of endogenous Tau
Paradise, V.; Sabu, M.; Bafia, J.; Sharif, N. A.; Nguyen, C.; Dhanraj Mukim, R.; Konrad-Vicario, K. D.; Wang, X.; Corjuc, B. T.; Fu, J.; Maldonado, G.; Ndubisi, J.; Strickland, M.; Figueroa, H.; Almeida, D. L.; Hyman, B. T.; Holtzman, D. M.; Nuriel, T.; Ramachandran, K. V.
10.1101/2022.11.29.518293 — neuroscience — Posted on 2023-04-19
1652 Variational Log-Gaussian Point-Process Methods for Grid Cells
Rule, M. E.; Vayalambrone, P. C.; Krstulovic, M.; Bauza, M.; Krupic, J.; O'Leary, T.
10.1101/2023.03.18.533177 — neuroscience — Posted on 2023-04-19
1655 ZygosityPredictor
Rheinnecker, M.; Froehlich, M.; Ruebsam, M.; Paramasivam, N.; Heilig, C. E.; Froehling, S.; Schlenk, R. F.; Hutter, B.; Huebschmann, D.
10.1101/2023.03.09.531877 — bioinformatics — Posted on 2023-04-19
1658 Topographic barriers drive the pronounced genetic subdivision of a range-limited fossorial rodent
Reuber, V. M.; Westbury, M. V.; Rey-Iglesia, A.; Asefa, A.; Farwig, N.; Miehe, G.; Opgenoorth, L.; Sumbera, R.; Wraase, L. M.; Wube, T.; Lorenzen, E. D.; Schabo, D. G.
10.1101/2023.04.06.535856 — evolutionary biology — Posted on 2023-04-19
1661 Conservation and diversification of the molecular functions of YTHDF proteins
Flores-Tellez, D.; Tankmar, M. D.; von Büllow, S.; Chen, J.; Lindorff-Larsen, K.; Brodersen, P.; Arribas-Hernandez, L.
10.1101/2022.10.19.512826 — molecular biology — Posted on 2023-04-19
1662 In Vitro Modeling of CD8 T Cell Exhaustion Enables CRISPR Screening to Reveal a Role for BHLHE40
Wu, J. E.; Manne, S.; Ngiow, S. F.; Baxter, A. E.; Huang, H.; Freilich, E.; Clark, M. L.; Lee, J. H.; Chen, Z.; Khan, O.; Staupe, R. P.; Huang, Y. J.; Shi, J.; Giles, J. R.; Wherry, E. J.
10.1101/2023.04.17.537229 — immunology — Posted on 2023-04-19
1664 Ultrastructure of the nebenkern during spermatogenesis in the praying mantid Hierodula membranacea
Köckert, M.; Okafornta, C. W.; Hill, C.; Ryndyk, A.; Striese, C.; Müller-Reichert, T.; Paliulis, L.; Fabig, G.
10.1101/2023.04.16.537100 — cell biology — Posted on 2023-04-19
1665 ER-dependent membrane repair of mycobacteria-induced vacuole damage
Anand, A.; Mazur, A.-C.; Rosell-Arevalo, P.; Franzkoch, R.; Breitsprecher, L.; Listian, S. A.; Hüttel, S. V.; Müller, D.; Schäfer, D. G.; Vormittag, S.; Hilbi, H.; Maniak, M.; Gutierrez, M.; Barisch, C.
10.1101/2023.04.17.537276 — cell biology — Posted on 2023-04-19
1672 Proteomes Reveal Metabolic Capabilities of Yarrowia lipolytica for Biological Upcycling of Polyethylene into High-Value Chemicals
Walker, C.; Mortensen, M.; Poudel, B.; Cotter, C.; Okekeogbu, I.; Ryu, S.; Khomami, B.; Giannone, R. J.; Laursen, S.; Trinh, C. T.
10.1101/2023.04.17.537167 — systems biology — Posted on 2023-04-18
1673 An accurate and interpretable model to predict antimicrobial resistance in One Health settings
Chung, H. C.; Foxx, C. L.; Hicks, J. A.; Stuber, T. P.; Friedberg, I.; Dorman, K. S.; Harris, B. N.
10.1101/2023.04.18.537400 — bioinformatics — Posted on 2023-04-18
1677 BATF relieves hepatic steatosis by inhibiting PD1 and promoting energy metabolism
Zhang, Z.; Liao, Q.; Pan, T.; Yu, L.; Luo, Z.; Su, S.; Liu, S.; Hou, M.; Li, Y.; Damba, T.; Liang, Y.; Zhou, L.
10.1101/2023.04.18.537352 — molecular biology — Posted on 2023-04-18
1679 Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis
COULIS, G.; Jaime, D.; Guerrero-Juarez, C.; Kastenschmidt, J.; Farahat, P.; Nguyen, Q.; Pervolarakis, N.; McLinden, K.; Thurlow, L.; Movahedi, S.; Hughes, B.; Duarte, J.; Sorn, A.; Montoya, E.; Mozaffar, I.; Dragan, M.; Othy, S.; Joshi, T.; Hans, C.; Kimonis, V.; MacLean, A.; Nie, Q.; Wallace, L.; Harper, S.; Mozaffar, T.; Hogarth, M.; Bhattacharya, S.; Jaiswal, J.; Golann, D.; Su, Q.; Kessenbrock, K.; Stec, M.; Spencer, M.; Zamudio, J.; Villalta, A.
10.1101/2023.04.18.537253 — immunology — Posted on 2023-04-18
1680 Class imbalance should not throw you off balance: Choosing the right classifiers and performance metrics for brain decoding with imbalanced data
Thölke, P.; Mantilla-Ramos, Y.-J.; Abdelhedi, H.; Maschke, C.; Dehgan, A.; Harel, Y.; Kemtur, A.; Berrada, L. M.; Sahraoui, M.; Young, T.; Bellemare, A.; El Khantour, C.; Landry, M.; Pascarella, A.; Hadid, V.; Combrisson, E.; O'Byrne, J.; Jerbi, K.
10.1101/2022.07.18.500262 — neuroscience — Posted on 2023-04-18
1681 Integrated Multi-Omics Analysis of Brain Aging in Female Nonhuman Primates Reveals Altered Signaling Pathways Relevant to Age-Related Disorders
Cox, L. A.; Puppala, S.; Chan, J.; Zimmerman, K.; Hamid, Z.; Ampong, I.; Huber, H. F.; Li, G.; Jadhav, A. Y.; Wang, B.; Li, C.; Baxter, M. G.; Shively, C.; Clarke, G.; Register, T. C.; Nathanielsz, P. W.; Olivier, M.
10.1101/2022.11.01.514742 — systems biology — Posted on 2023-04-18
1682 Assembling membraneless organelles from de novo designed proteins
Hilditch, A. T.; Romanyuk, A.; Cross, S. J.; Obexer, R.; McManus, J. J.; Woolfson, D. N.
10.1101/2023.04.18.537322 — synthetic biology — Posted on 2023-04-18
1688 The hagfish genome and the evolution of vertebrates
Marletaz, F.; Timoshevskaya, N.; Timoshevskiy, V.; Simakov, O.; Parey, E.; Gavriouchkina, D.; Suzuki, M.; Kubokawa, K.; Brenner, S.; Smith, J.; Rokhsar, D. S.
10.1101/2023.04.17.537254 — genomics — Posted on 2023-04-18
1689 Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics
Chan, T. F.; Rui, X.; Conti, D. V.; Fornage, M.; Graff, M.; Haessler, J.; Haiman, C.; Highland, H. M.; Jung, S. Y.; Kenny, E.; Kooperberg, C.; Le Marchland, L.; North, K. E.; Tao, R.; Wojcik, G.; Gignoux, C. R.; PAGE Consortium, ; Chiang, C. W.; Mancuso, N.
10.1101/2023.04.10.536252 — genetics — Posted on 2023-04-18
1690 In Vivo mRNA Hacking with Staple Oligomers Prevents Myocardial Hypertrophy
Katsuda, Y.; Kamura, T.; Kida, T.; Saeki, T.; Itsuki, Y.; Kato, Y.; Nakamura, T.; Nishida, M.; Kitamura, Y.; Ihara, T.; Hagihara, M.; Sato, S.-i.
10.1101/2023.04.18.537290 — molecular biology — Posted on 2023-04-18
1692 A palmitoyl transferase chemical genetic system to map ZDHHC-specific S-acylation
Ocasio, C. A.; Baggelaar, M. P.; Sipthorp, J.; Losada de la Lastra, A.; Volaric, J.; Soudy, C.; Storck, E. M.; Palma-Duran, S. A.; MacRae, J. I.; Tomic, G.; Carr, L.; Downward, J.; Eggert, U.; Tate, E. W.
10.1101/2023.04.18.537386 — molecular biology — Posted on 2023-04-18
1694 Artificial intelligence redefines RNA virus discovery
Hou, X.; He, Y.; Fang, P.; Mei, S.-Q.; Xu, Z.; Wu, W.-C.; Tian, J.-H.; Zhang, S.; Zeng, Z.-Y.; Gou, Q.-Y.; Xin, G.-Y.; Le, S.-J.; Xia, Y.-Y.; Zhou, Y.-L.; Hui, F.-M.; Pan, Y.-F.; Eden, J.-S.; Yang, Z.-H.; Han, C.; Shu, Y.-L.; Guo, D.; Li, J.; Holmes, E. C.; Li, Z.-R.; Shi, M.
10.1101/2023.04.18.537342 — microbiology — Posted on 2023-04-18
1699 Folding kinetics of an entangled protein
Salicari, L.; Baiesi, M.; Orlandini, E.; Trovato, A.
10.1101/2023.04.17.537117 — biophysics — Posted on 2023-04-18
1702 A biophysical rationale for the selective inhibition of PTP1B over TCPTP by nonpolar terpenoids
Friedman, A. J.; Padgette, H. M.; Kramer, L.; Liechty, E. T.; Donovan, G. W.; Fox, J. M.; Shirts, M. R.
10.1101/2023.04.17.537234 — bioengineering — Posted on 2023-04-18
1705 Integrating gene annotation with orthology inference at scale
Kirilenko, B. M.; Munegowda, C.; Osipova, E.; Jebb, D.; Sharma, V.; Blumer, M.; Morales, A.; Ahmed, A.-W.; Kontopoulos, D.-G.; Hilgers, L.; Lindblad-Toh, K.; Karlsson, E. K.; Zoonomia Consortium, ; Hiller, M.
10.1101/2022.09.08.507143 — genomics — Posted on 2023-04-18
1706 Sex-specific Associations in the Hybrid Mouse Diversity Panel help define genetic architecture
Miller, A. K.; Pan, C.; Lusis, A. J.; Crawford, D. C.; Williams, S. M.; Buchner, D. A.
10.1101/2022.09.28.509932 — genetics — Posted on 2023-04-18
1709 Spatial phylogenetics of Fagales: Investigating the history of temperate forests
Folk, R. A.; Siniscalchi, C. M.; Doby, J.; Kates, H.; Manchester, S. R.; Soltis, P. S.; Soltis, D. E.; Guralnick, R. P.; Belitz, M.
10.1101/2023.04.17.537249 — evolutionary biology — Posted on 2023-04-18
1710 The genomic landscape of adaptation to a new host plant
Nilsson, K. J.; Steward, R. A.; Ortega Gimenez, J.; Nolen, Z. J.; Yan, C.; Huang, Y.; Ayala Lopez, J.; Runemark, A.
10.1101/2023.04.17.537225 — evolutionary biology — Posted on 2023-04-18
1711 Climate, host and geography shape insect and fungal communities of trees
Franic, I.; Allan, E.; Prospero, S.; Adamson, K.; Attorre, F.; Auger-Rozenberg, M. A.; Augustin, S.; Avtzis, D.; Baert, W.; Barta, M.; Bauters, K.; Bellahirech, A.; Boron, P.; Braganca, H.; Brestovanska, T.; Brurberg, M. B.; Burgess, T.; Burokiene, D.; Cerny, K.; Cleary, M.; Corley, J.; Coyle, D. R.; Csoka, G.; Davydenko, K.; de Groot, M.; Diez, J. J.; Dogmus Lehtijarvi, H. T.; Drenkhan, R.; Edwards, J.; Elsafy, M.; Eotvos, C. B.; Falko, R.; Fan, J.; Feddern, N.; Furjes-Miko, A.; Gossner, M.; Grad, B.; Hartmann, M.; Havrdova, L.; Horakova, M. K.; Hrabetova, M.; Justesen, M. J.; Kacprzyk, M.; K
10.1101/2023.04.17.537195 — ecology — Posted on 2023-04-18
1712 Engineering Nme2Cas9 Adenine Base Editors with Improved Activity and Targeting Scope
Bamidele, N.; Zhang, H.; Dong, X.; Gaston, N.; Cheng, H.; Kelly, K.; Watts, J. K.; Xie, J.; Gao, G.; Sontheimer, E. J.
10.1101/2023.04.14.536905 — molecular biology — Posted on 2023-04-18
1713 Universal recording of cell-cell contacts in vivo for interaction-based transcriptomics
Nakandakari-Higa, S.; Canesso, M. C. C.; Walker, S.; Chudnovskiy, A.; Bilanovic, J.; Jacobsen, J. T.; Parigi, S. M.; Fiedorczuk, K.; Fuchs, E.; Bilate, A. M.; Pasqual, G.; Mucida, D.; Pritykin, Y.; Victora, G. D.
10.1101/2023.03.16.533003 — immunology — Posted on 2023-04-18
1714 Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-typespecific vulnerabilities in human brain organoids
Pak, C.; Sebastian, R.; Jin, K.; Pavon, N.; Bansal, R.; Potter, A.; Song, Y.; Babu, J.; Gabriel, R.; Sun, Y.; Aronow, B. J.
10.1101/2022.08.24.505165 — neuroscience — Posted on 2023-04-18
1715 pGG-PIP: A GreenGate (GG) entry vector collection with Plant Immune system Promoters (PIP)
Calabria, J.; Rast-Somssich, M. I.; Wang, L.; Chen, H.-W.; Watt, M.; Idnurm, A.; Persson, S.; Somssich, M.
10.1101/2022.12.20.521163 — plant biology — Posted on 2023-04-18
1717 Efficient and Robust Search of Microbial Genomes via Phylogenetic Compression
Brinda, K.; Lima, L.; Pignotti, S.; Quinones-Olvera, N.; Salikhov, K.; Chikhi, R.; Kucherov, G.; Iqbal, Z.; Baym, M.
10.1101/2023.04.15.536996 — bioinformatics — Posted on 2023-04-18
1718 BayesDeBulk: A Flexible Bayesian Algorithm for the Deconvolution of Bulk Tumor Data
Petralia, F.; Krek, A.; Calinawan, A. P.; Charytonowicz, D.; Sebra, R.; Feng, S.; Gosline, S. J.; Pugliese, P.; Kennedy, J. J.; Paulovich, A. G.; Ceccarelli, M.; Wang, P.
10.1101/2021.06.25.449763 — bioinformatics — Posted on 2023-04-18
1720 Telomouse - a mouse model with human-length telomeres generated by a single amino acid change in RTEL1
Smoom, R.; Lee May, C.; Ortiz, V.; Tigue, M.; Kolev, H.; Rowe, M.; Reizel, Y.; Morgan, A.; Egyes, N.; Lichtental, D.; Skordalakes, E.; Kaestner, K. H.; Tzfati, Y.
10.1101/2021.06.06.447246 — genetics — Posted on 2023-04-18
1721 Female reed warblers in social pairs with low MHC dissimilarity achieve higher MHC compatibility through random extra-pair matings
Halupka, L.; O'Connor, E. A.; Strandh, M.; Sztwiertnia, H.; Klimczuk, E.; Hasselquist, D.; Westerdahl, H.
10.1101/2023.04.17.537178 — ecology — Posted on 2023-04-18
1722 Staying in control: characterising the mechanisms underlying cognitive control in high and low arousal states
Alameda, C.; Avancini, C.; Sanabria, D.; Bekinschtein, T. A.; Canales-Johnson, A.; Ciria, L. F.
10.1101/2023.04.17.536548 — neuroscience — Posted on 2023-04-18
1723 Human fetal virtual histology with X-ray phase contrast imaging
Verot, P.-L.; Charnay, L.; Tavakoli, C.; Singh, S.; Quenot, L.; Sole Cruz, E.; Barnat, M.; Humbert, S.; Dommergues, M.; Durr, A.; Piolat, C.; Rabattu, P. Y.; Brun, E.
10.1101/2023.04.18.537316 — developmental biology — Posted on 2023-04-18
1724 Large-scale brain signatures of fluid dynamics and responsiveness linked to consciousness
Breyton, M.; Fousek, J.; Rabuffo, G.; Sorrentino, P.; Kusch, L.; Massimini, M.; Petkoski, S.; Jirsa, V.
10.1101/2023.04.18.537321 — neuroscience — Posted on 2023-04-18
1725 Plasma endocannabinoids in cocaine dependence and their interaction with cocaine craving and metabotropic glutamate receptor 5 density in the human brain
Kroll, S. L.; Hulka, L. M.; Kexel, A.-K.; Vonmoos, M.; Preller, K. H.; Treyer, V.; Ametamey, S.; Baumgartner, M. R.; Boost, C.; Pahlisch, F.; Rohleder, C.; Leweke, F. M.; Quednow, B. B.
10.1101/2023.04.18.537293 — neuroscience — Posted on 2023-04-18
1726 Depletion of neurocan in the prefrontal cortex impairs temporal order recognition, cognitive flexibility and perisomatic GABAergic innervation
Baidoe-Ansah, D.; Mirzapourdelavar, H.; Carceller, H.; Perez, M.; Strackeljan, L.; Garcia, B.; Seidenbecher, C. I.; Kaushik, R.; Nacher, J.; Dityatev, A.
10.1101/2023.04.18.537277 — neuroscience — Posted on 2023-04-18
1728 Measuring the perception and metacognition of time
Cropper, S. J.; Little, D. R.; Xu, L.; Bruno, A.; Johnston, A.
10.1101/2023.04.18.537334 — neuroscience — Posted on 2023-04-18
1729 BOUNTI: Brain vOlumetry and aUtomated parcellatioN for 3D feTal MRI
Uus, A. U.; Kyriakopoulou, V.; Makropoulos, A.; Fukami-Gartner, A.; Cromb, D.; Davidson, A.; Cordero-Grande, L.; Price, A. N.; Grigorescu, I.; Williams, L. Z. J.; Robinson, E. C.; Lloyd, D.; Pushparajah, K.; Story, L.; Hutter, J.; Counsell, S. J.; Edwards, A. D.; Rutherford, M. A.; Hajnal, J. V.; Deprez, M.
10.1101/2023.04.18.537347 — neuroscience — Posted on 2023-04-18
1733 Computational design of non-porous, pH-responsive antibody nanoparticles
Yang, E. C.; Divine, R.; Miranda, M. C.; Borst, A. J.; Sheffler, W.; Zhang, J. Z.; Decarreau, J.; Sarajovi, A.; Abedi, M.; Goldbach, N.; Ahlrichs, M.; Dobbins, C.; Hand, A.; Cheng, S.; Lamb, M.; Levine, P. M.; Chan, S.; Skotheim, R.; Fallas, J.; Ueda, G.; Lubner, J.; Somiya, M.; Khmelinskaia, A.; King, N. P.; Baker, D.
10.1101/2023.04.17.537263 — bioengineering — Posted on 2023-04-18
1736 Genetic drift and genome reduction in the plant pathogen Candidatus Liberibacter solanacearum shapes a new enzyme in lysine biosynthesis.
Gilkes, J. M.; Frampton, R. A.; Board, A. J.; Hudson, A. O.; Price, T.; Crittenden, D. L.; Muscroft-Taylor, A. C.; Sheen, C. R.; Smith, G. R.; Dobson, R. C. J.
10.1101/2023.04.17.537279 — evolutionary biology — Posted on 2023-04-18
1737 Metabolic complexity increases adaptability
Fritzemeier, C. J.; Ghaffarinasab, S.; Lieder, F.; Szappanos, B.; Jarre, F.; Papp, B.; Pal, C.; Lercher, M. J.
10.1101/2023.04.17.537065 — evolutionary biology — Posted on 2023-04-18
1738 Cell Type-Specific Regulation by a Heptad of Transcription Factors in Human Hematopoietic Stem and Progenitor Cells
Subramanian, S.; Thoms, J.; Huang, Y.; Cornejo, P.; Koch, F. C.; Jacquelin, S.; Shen, S.; Song, E.; Joshi, S.; Brownlee, C.; Woll, P. S.; Fajardo, D. C.; Beck, D.; Curtis, D. J.; Yehson, K.; Antonenas, V.; O'Brien, T.; Trickett, A.; Powell, J. A.; Lewis, I. D.; Pitson, S. M.; Gandhi, M. K.; Lane, S. W.; Vafaee, F.; Wong, E.; Gottgens, B.; Rokny, H. A.; Wong, J. W. H.; Pimanda, J. E.
10.1101/2023.04.18.537282 — developmental biology — Posted on 2023-04-18
1739 A quantitative characterization of early neuron generation in the developing zebrafish telencephalon.
Casas Gimeno, G.; Dvorianinova, E.; Lembke, C.-S.; Dijkstra, E. S.; Abbas, H.; Liu, Y.; Paridaen, J. T. M. L.
10.1101/2023.04.18.537159 — developmental biology — Posted on 2023-04-18
1742 Combined inhibition of homologous PTPN1 and PTPN2 is synergistic in enhancing CD8 T cell effector functions.
Perez-Quintero, L. A.; Martinez-Cordoba, Z.; Carli, C.; Poirier, A.; Kamyabiazar, S.; Feng, C.-H.; Pacis, A.; Zolotarov, Y.; Pike, K.-A.; Delisle, J.-S.; Tremblay, M. L.
10.1101/2023.04.17.537264 — immunology — Posted on 2023-04-18
1743 Sentence superiority in the reading brain
Dufau, S. E.; Yeaton, J. D.; Badier, J.-M.; Chen, S.; Holcomb, P. J.; Grainger, J.
10.1101/2023.04.17.534292 — neuroscience — Posted on 2023-04-18
1744 RGS6 mediates exercise-induced recovery of hippocampal neurogenesis, learning, and memory in an Alzheimer's mouse model
Spicer, M. M.; Yang, J.; Fu, D. A.; DeVore, A. N.; Lauffer, M.; Sayar-Atasoy, N.; Atasoy, D. M.; Fisher, R. A.
10.1101/2023.04.17.537272 — neuroscience — Posted on 2023-04-18
1747 Impact of light pollution at night on male reproductive success in Japanese medaka (Oryzias latipes)
Closs, L. E.; Royan, M. R.; Sayyari, A.; Mayer, I.; Weltzien, F.-A.; Baker, D. M.; Fontaine, R.
10.1101/2023.04.17.536935 — zoology — Posted on 2023-04-18
1749 NFκB nuclear dynamics orchestrate inflammatory aging
Tabata, S.; Matsuda, K.; Nagai, K.; Izumi, Y.; Takahashi, M.; Motomura, Y.; Nagasato, A. I.; Shimma, S.; Moro, K.; Bamba, T.; Okada, M.
10.1101/2023.04.18.536673 — systems biology — Posted on 2023-04-18
1750 Engineering genetic circuits in receiver cells for diffusion-based molecular data communications
Durmaz, M. G.; Tulluk, N.; Aksoy, R. D.; Yilmaz, H. B.; Yang, B.; Wipat, A.; Pusane, A. E.; Mısırlı, G.; Tugcu, T.
10.1101/2023.04.18.536609 — synthetic biology — Posted on 2023-04-18
1751 Amyloplast sedimentation repolarizes LAZYs to achieve gravity sensing in plants
Chen, J.; Yu, R.; Li, N.; Deng, Z.; Zhang, X.; Zhao, Y.; Qu, C.; Yuan, Y.; Pan, Z.; Zhou, Y.; Li, K.; Wang, J.; Chen, Z.; Wang, X.; Wang, X.; Dong, J.; Deng, X. W.; Chen, H.
10.1101/2023.04.17.537121 — plant biology — Posted on 2023-04-18
1753 Genetic Mapping of SNP Markers and Candidate Genes Associated with Day-Neutral Flowering in Cannabis sativa L.
Garfinkel, A. R.; Wilkerson, D. G.; Chen, H.; Smart, L. B.; Rojas, B. M.; Getty, B. A.; Michael, T. P.; Crawford, S.
10.1101/2023.04.17.537043 — plant biology — Posted on 2023-04-18
1755 MCU gain- and loss-of-function models define the duality of mitochondrial calcium uptake in heart failure
Garbincius, J. F.; Luongo, T. S.; Lambert, J. P.; Mangold, A. S.; Murray, E. K.; Hildebrand, A. N.; Jadiya, P.; Elrod, J. W.
10.1101/2023.04.17.537222 — physiology — Posted on 2023-04-18
1756 Metformin Impairs Intestinal Fructose Metabolism
Tong, W.; Hannou, S. A.; Sargsyan, A.; Zhang, G.-F.; Grimsrud, P. A.; Astapova, I.; Herman, M. A.
10.1101/2023.04.17.537251 — physiology — Posted on 2023-04-18
1758 Pharmacological activation of constitutive androstane receptor induces female-specific modulation of hepatic metabolism
Huillet, M.; Lasserre, F.; Gratacap, M.-P.; Engelmann, B.; Bruse, J.; Polizzi, A.; Fougeray, T.; Martin, C. M. P.; Rives, C.; Fougerat, A.; Naylies, C.; Lippi, Y.; Garcia, G.; Rousseau-Bacquie, E.; Canlet, C.; Debrauwer, L.; Rolle-Kampczyk, U.; Von Bergen, M.; Payrastre, B.; Boutet-Robinet, E.; Gamet-Payrastre, L.; Guillou, H.; Loiseau, N.; Ellero-Simatos, S.
10.1101/2023.04.17.537169 — pharmacology and toxicology — Posted on 2023-04-18
1759 Growth Hormone Accelerates Recovery From Acetaminophen-Induced Murine Liver Injury
Everton, E.; del Rio Moreno, M.; Villacorta-Martin, C.; Singh Bawa, P.; Lindstrom-Vautrin, J.; Muramatsu, H.; Rizvi, F.; Smith, A. R.; Tam, Y.; Pardi, N.; Kineman, R.; Waxman, D. J.; Gouon-Evans, V.
10.1101/2023.04.17.537197 — pathology — Posted on 2023-04-18
1760 VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis
Rizvi, F.; Lee, Y.-R.; Diaz-Aragon, R.; So, J.; Florentino, R. M.; Smith, A. R.; Everton, E.; Ostrowska, A.; Jung, K.; Tam, Y.; Muramatsu, H.; Pardi, N.; Weissman, D.; Soto-Gutierrez, A.; Shin, D.; Gouon-Evans, V.
10.1101/2023.04.17.537186 — pathology — Posted on 2023-04-18
1761 Ca2+/Calmodulin Dependent Protein Kinase Kinase-2 (CaMKK2) promotes Protein Kinase G (PKG)-dependent actin cytoskeletal assembly to increase tumor metastasis
Mukherjee, D.; Previs, R. A.; Haines, C. N.; Al Abo, M.; Juras, P. K.; Strickland, K. C.; Chakraborty, B.; Artham, S.; Whitaker, R.; Hebert, K. L.; Fontenot, J.; Patierno, S. R.; Freedman, J. A.; Lau, F. H.; Burow, M.; Chang, C.-Y.; McDonnell, D. P.
10.1101/2023.04.17.536051 — cancer biology — Posted on 2023-04-18
1765 Barley HvNIP2;1 aquaporin permeates water, metalloids, saccharides, and ion pairs due to structural plasticity and diversification
Venkataraghavan, A.; Kim, H.; Schwerdt, J. G.; Gulyuk, A. V.; Singh, A.; Yingling, Y. G.; Tyerman, S. D.; Hrmova, M.
10.1101/2023.04.17.537278 — biophysics — Posted on 2023-04-18
1774 Single worm long read sequencing reveals genome diversity in free-living nematodes
Lee, Y.-C.; Lee, H.-H.; Ke, H.-M.; Liu, Y.-C.; Wang, M.-C.; Tseng, Y.-C.; Kikuchi, T.; Tsai, I. J.
10.1101/2023.04.17.537128 — genomics — Posted on 2023-04-18
1775 Nucleosome reorganisation in breast cancer tissues
Jacob, D. R.; Guiblet, W. M.; Mamayusupova, H.; Shtumpf, M.; Ruje, L.; Ciuta, I.; Gretton, S.; Correa, C.; Dellow, E.; Agrawal, S. P.; Shafiei, N.; Drobysevskaja, A.; Armstrong, C. M.; Lam, J. D. G.; Vainshtein, Y.; Clarkson, C. T.; Thorn, G. J.; Sohn, K.; Madapura, P. B.; Chandrasekharan, S.; Brooke, G. N.; Klenova, E.; Zhurkin, V. B.; Teif, V. B.
10.1101/2023.04.17.537031 — genomics — Posted on 2023-04-18
1777 Sperm Whales Demographics in the Gulf of Alaska and Bering Sea/Aleutian Islands: An Overlooked Female Habitat
Posdaljian, N.; Solsona-Berga, A.; Hildebrand, J. A.; Soderstjerna, C.; Wiggins, S. M.; Lenssen, K.; Baumann-Pickering, S.
10.1101/2023.04.16.537097 — ecology — Posted on 2023-04-18
1778 Biotic interactions explain seasonal dynamics of the alpine soil microbiome
Fiore-Donno, A. M.; Freudenthal, J.; Borg Dahl, M.; Rixen, C.; Urich, T.; Bonkowski, M.
10.1101/2023.04.17.537150 — ecology — Posted on 2023-04-18
1781 Variability in donor lung culture and relative humidity impact the stability of 2009 pandemic H1N1 influenza virus on nonporous surfaces
Qian, Z.; Morris, D. H.; Avery, A.; Kormuth, K.; Valerie, L. S. M.; Myerburg, M. M.; Lloyd-Smith, J. O.; Marr, L.; Lakdawala, S.
10.1101/2023.04.17.537242 — microbiology — Posted on 2023-04-18
1782 Loss-of-function mutation in Omicron variants reduces spike protein expression and attenuates SARS-CoV-2 infection
Vu, M. N.; Morris, D. R.; Alvarado, R. E.; Lokugamage, K. G.; Zhou, Y.; Estes, L. K.; McLeland, A. M.; Schindewolf, C.; Plante, J. A.; Ahearn, Y. P.; Morgan, A. L.; Meyers, W. M.; Murray, J. T.; Weaver, S.; Walker, D. H.; Russell, W. K.; Routh, A. L.; Plante, K. S.; Menachery, V. D.
10.1101/2023.04.17.536926 — microbiology — Posted on 2023-04-18
1783 A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication and pathogenesis in vivo
Taha, T. Y.; Suryawanshi, R. K.; Chen, I. P.; Correy, G. J.; O'Leary, P. C.; Jogalekar, M. P.; McCavitt-Malvido, M.; Diolaiti, M.; Kimmerly, G. R.; Tsou, C.-L.; Martinez-Sobrido, L.; Krogan, N. J.; Ashworth, A.; Fraser, J. S.; Ott, M.
10.1101/2023.04.18.537104 — microbiology — Posted on 2023-04-18
1784 Adenovirus protein VII binds the A-box of HMGB1 to repress interferon responses.
Arnold, E. A.; Kaai, R. J.; Leung, K.; Brinkley, M. R.; Kelnhofer-Millevolte, L. E.; Guo, M. S.; Avgousti, D. C.
10.1101/2023.04.17.537247 — microbiology — Posted on 2023-04-18
1785 Oncolytic Newcastle disease virus enhanced apoptosis in colorectal cancer cell lines
Ginting, T. E.; Hidayat, N. R.; Cornelia, V.; Larasati, Y. O.; Zarkasie, K.; Yusuf, I.
10.1101/2023.04.16.537098 — immunology — Posted on 2023-04-18
1786 Topographical analysis of immune cell interactions reveals a biomechanical signature for immune cytolysis
de Jesus, M.; Settle, A. H.; Vorselen, D.; Gaetjens, T. K.; Galiano, M.; Wong, Y. Y.; Fu, T.-M.; Santosa, E.; Winer, B. Y.; Tamzalit, F.; Wang, M. S.; Bao, Z.; Sun, J. C.; Shah, P.; Theriot, J. A.; Abel, S. M.; Huse, M.
10.1101/2023.04.16.537078 — immunology — Posted on 2023-04-18
1788 Transformers enable accurate prediction of acute and chronic chemical toxicity in aquatic organisms
Gustavsson, M.; Kall, S.; Svedberg, P.; Inda-Diaz, J. S.; Molander, S.; Coria, J.; Backhaus, T.; Kristiansson, E.
10.1101/2023.04.17.537138 — pharmacology and toxicology — Posted on 2023-04-18
1789 Folding kinetics of an entangled protein
Salicari, L.; Baiesi, M.; Orlandini, E.; Trovato, A.
10.1101/2023.04.17.537117 — biophysics — Posted on 2023-04-18
1790 Investigation of refractive index dynamics during embryo development using digital holographic microscopy
Dwapanyin, G. O.; Chow, D. J. X.; Tan, T. C. Y.; Dubost, N. S.; Morizet, J. M.; Dunning, K. R.; Dholakia, K.
10.1101/2023.04.17.537152 — biophysics — Posted on 2023-04-18
1793 nELISA: A high-throughput, high-plex platform enables quantitative profiling of the secretome
Dagher, M.; Ongo, G.; Robichaud, N.; Kong, J.; Rho, W.; Teahulos, I.; Tavakoli, A.; Bovaird, S.; Merjaneh, S.; Tan, A.; Edwardson, K.; Scheepers, C.; Ng, A.; Hajjar, A.; Lee, A.; DeCorwin-Martin, P.; Rasool, S.; Huang, J.; Han, Y.; Chandrasekaran, S. N.; Miller, L.; Kost-Alimova, M.; Skepner, A.; Singh, S.; Munzar, J.; Carpenter, A. E.; Juncker, D.
10.1101/2023.04.17.535914 — bioengineering — Posted on 2023-04-18
1794 GWAS and genomic selection for marker-assisted development of sucrose enriched soybean cultivars
Riaz, A.; Raza, Q.; Kumar, A.; Dean, D.; Chiwina, K.; Phiri, T. M.; Thomas, J.; Shi, A.
10.1101/2023.04.16.537083 — genomics — Posted on 2023-04-18
1796 Stray cats and dogs carrying zoonotic Enterocytozoon bieneusi genotype D in China: a public health concern
Zhang, Y.; Zhang, Y.; Mi, R.; Xia, L.; Han, H.; Ma, T.; Gong, H.; Huang, Y.; Han, X.; Chen, Z.
10.1101/2023.04.17.537122 — genetics — Posted on 2023-04-18
1797 Horizontal Transfer of Histone H3 by Mammalian Cells
Sulkowski, P. L.; Nicholson, H. E.; Li, M. Z.; Perrimon, N.; Liu, Z.; Kaelin, W. G.
10.1101/2021.06.30.450524 — cell biology — Posted on 2023-04-18
1800 Granulins rescue inflammation, lysosome dysfunction, and neuropathology in a mouse model of progranulin deficiency.
Root, J.; Mendsaikhan, A.; Nandy, S.; Taylor, G.; Wang, M.; Troiano Araujo, L.; Merino, P.; Ryu, D.; Holler, C.; Thompson, B. M.; Astarita, G.; Blain, J.-F.; Kukar, T.
10.1101/2023.04.17.536004 — neuroscience — Posted on 2023-04-18
1803 Cryo-EM structure of the folded-back state of human β-cardiac myosin
Grinzato, A.; Auguin, D.; Kikuti, C.; Nandwani, N.; Moussaoui, D.; Pathak, D.; Kandiah, E.; Ruppel, K. M.; Spudich, J. A.; Houdusse, A.; Robert-Paganin, J.
10.1101/2023.04.15.536999 — biophysics — Posted on 2023-04-18
1804 mitoSpliter: a mitochondrial RNA variants-based method for single-cell RNA-seq analysis of multiplexed samples
Lin, X.; Chen, Y.; Lin, L.; Yin, K.; Wang, X.; Guo, Y.; Wu, Z.; Zhang, Y.; Li, J.; Yang, C.; Song, J.
10.1101/2023.04.16.537058 — bioinformatics — Posted on 2023-04-18
1808 Home security cameras as a tool for behavior observations and science equity
Goolsby, B. C.; Fischer, M.-T.; Pareja-Mejia, D.; Lewis, A. R.; Raboisson, G.; O'Connell, L. A.
10.1101/2023.04.17.537238 — animal behavior and cognition — Posted on 2023-04-18
1810 Dominance between self-incompatibility alleles determines the mating system of Capsella allopolyploids
Duan, T.; Zhang, Z.; Genete, M.; Poux, C.; Sicard, A.; Lascoux, M.; Castric, V.; Vekemans, X.
10.1101/2023.04.17.537155 — evolutionary biology — Posted on 2023-04-18
1811 Netrin-1 directs vascular patterning and maturity in the developing kidney
Honeycutt, S. E.; N'Guetta, P.-E. Y.; Hardesty, D. M.; Xiong, Y.; Cooper, S. L.; O'Brien, L. L.
10.1101/2023.04.14.536975 — developmental biology — Posted on 2023-04-18
1812 Elucidation of the antiviral mechanism of natural therapeutic molecules Herbacetin and Caffeic acid phenethyl ester against Chikungunya and Dengue virus
Bhutkar, M.; Rani, R.; Pathak, A.; Kothiala, A.; Mahajan, S.; Waghmode, B.; Kumar, R.; Singh, V.; Sircar, D.; Kumar, P.; Tomar, S.
10.1101/2022.05.31.494145 — microbiology — Posted on 2023-04-18
1817 Fluid restrictive resuscitation with high molecular weight hyaluronan infusion in early peritonitis-sepsis
Barrueta Tenhunen, A.; van der Heijden, J.; Skorup, P.; Maccarana, M.; Larsson, A.; Larsson, A.; Perchiazzi, G.; Tenhunen, J.
10.1101/2023.04.14.536966 — pharmacology and toxicology — Posted on 2023-04-18
1818 Gemcitabine plus nab-paclitaxel preserves skeletal and cardiac mass and function in a murine model of pancreatic cancer cachexia
Narasimhan, A.; Jengelley, D.; Huot, J.; Umberger, T.; Doud, E.; Mosley, A. L.; Wang, M.; Zhong, X.; Counts, B.; Rupert, J.; Young, A.; Bonetto, A.; Horan, D.; Robling, A. G.; Fishel, M.; Kelley, M.; Koniaris, L.; Zimmers, T.
10.1101/2023.04.15.536434 — cancer biology — Posted on 2023-04-18
1820 Humic substances mitigate adverse effects of elevated temperature with potentially critical repercussions for coral reef resilience
Stuij, T. M.; Cleary, D. F. R.; de Voogd, N. J.; Rocha, R. J. M.; Polonia, A. R. M.; Silva, D. A. M.; Frommlet, J. C.; Louvado, A.; Huang, Y. M.; van der Windt, N.; Gomes, N. C. M.
10.1101/2023.04.14.536861 — ecology — Posted on 2023-04-18
1821 An Aging-Susceptible Circadian Rhythm Controls Cutaneous Antiviral Immunity
Kirchner, S.; Lei, V.; Kim, P.; Patel, M.; Shannon, J.; Corcoran, D.; Hughes, D.; Waters, D.; Dzirasa, K.; Erdmann, D.; Coers, J.; MacLeod, A.; Zhang, J.
10.1101/2023.04.14.536934 — immunology — Posted on 2023-04-18
1822 The integrity of dopaminergic and noradrenergic brain regions is associated with different aspects of late-life memory performance
Dahl, M. J.; Bachman, S. L.; Dutt, S.; Duezel, S.; Bodammer, N. C.; Lindenberger, U.; Kuehn, S.; Werkle-Bergner, M.; Mather, M.
10.1101/2022.10.12.511748 — neuroscience — Posted on 2023-04-18
1825 Mesenchymal stromal cells affect CD8 naive to memory subsets polarization by down-modulating IL12beta1 and IL2Ralpha signaling pathways
Papait, A.; Vertua, E.; Bonassi Signoroni, P.; Cargnoni, A.; Magatti, M.; Stefani, F. R.; Romoli, J.; Silini, A. R.; Parolini, O.
10.1101/2023.02.28.530378 — immunology — Posted on 2023-04-18
1827 Exploring the Interdependence of TKS4 and CD2AP: Implications for EMT Process and Early Detection in Colon Cancer
Kurilla, A.; Laszlo, L.; Takacs, T.; Tilajka, A.; Lukacs, L.; Novak, J.; Pancsa, R.; Buday, L.; Vas, V.
10.1101/2023.01.13.523903 — cancer biology — Posted on 2023-04-18
1828 Modeling Braf-induced thyroid cancer development and drug screening using pluripotent stem cell-derived organoids
Lasolle, H.; Schiavo, A. A.; Tourneur, A.; Gillotay, P.; da Fonseca, B. d. F.; Ceolin, L.; Monestier, O.; Aganahi, B.; Chomette, L.; Kizys, M. M. L.; Haenebalcke, L.; Pieters, T.; Goossens, S.; Haigh, J.; Detours, V.; Maia, A. L.; Costagliola, S.; Romitti, M.
10.1101/2023.03.30.534915 — cancer biology — Posted on 2023-04-18
1830 Phenotype prediction using biologically interpretable neural networks on multi-cohort multi-omics data
van Hilten, A.; van Rooij, J.; BIOS consortium, ; Ikram, M. A.; Niessen, W. J.; van Meurs, J. B. J.; Roshchupkin, G. V.
10.1101/2023.04.16.537073 — genomics — Posted on 2023-04-18
1833 Migratory herbivorous waterfowl couple the seed wave and the green wave during spring migration
Xu, F.; Wu, W.; Wei, J.; Xin, Q.; Wielstra, B.; La Sorte, F. A.; Ma, Z.; Lei, G.; Lei, J.; Wu, W.; Yang, Y.; Gong, P.; Xu, B.; Si, Y.
10.1101/2023.04.14.536842 — ecology — Posted on 2023-04-18
1834 The formation and closure of macropinocytic cups in a model system
Lutton, J.; Coker, H.; Paschke, P.; Munn, C.; King, J. S.; Kay, R.; Bretschneider, T.
10.1101/2022.10.07.511330 — cell biology — Posted on 2023-04-18
1838 Single-cell DNA Methylome and 3D Multi-omic Atlas of the Adult Mouse Brain
Liu, H.; Zeng, Q.; Zhou, J.; Bartlett, A.; Wang, B.-A.; Berube, P.; Tian, W.; Kenworthy, M.; Altshul, J.; Nery, J. R.; Chen, H.; Castanon, R. G.; Zu, S.; Li, Y. E.; Lucero, J.; Osteen, J. K.; Pinto-Duarte, A.; Lee, J.; Rink, J.; Cho, S.; Emerson, N.; Nunn, M.; O'Connor, C.; Yao, Z.; Tasic, B.; Smith, K. A.; Zeng, H.; Luo, C.; Dixon, J. R.; Ren, B.; Behrens, M. M.; Ecker, J. R.
10.1101/2023.04.16.536509 — genomics — Posted on 2023-04-18
1839 Associations between in vitro, in vivo and in silico cell classes in mouse primary visual cortex
Wei, Y.; Nandi, A.; Jia, X.; Siegle, J.; Denman, D.; Lee, S. Y.; Buchin, A.; Van Geit, W.; Mosher, C. P.; Olsen, S.; Anastassiou, C. A.
10.1101/2023.04.17.532851 — neuroscience — Posted on 2023-04-18
1840 Using rare genetic mutations to revisit structural brain asymmetry
Kopal, J.; Kumar, K.; Shafighi, K.; Saltoun, K.; Modenato, C.; Moreau, C. A.; Huguet, G.; Jean-Louis, M.; Martin, C.-O.; Saci, Z.; Younis, N.; Douard, E.; Jizi, K.; Beauchamp-Chatel, A.; Kushan, L.; Silva, A. I.; van den Bree, M. B. M.; Linden, D. E. J.; Owen, M. J.; Hall, J.; Lippe, S.; Draganski, B.; Sonderby, I. E.; Andreassen, O. A.; Glahn, D. C.; Thompson, P. M.; Bearden, C. E.; Zatorre, R.; Jacquemont, S.; Bzdok, D.
10.1101/2023.04.17.537199 — neuroscience — Posted on 2023-04-18
1841 Neural speech tracking benefit of lip movements predicts behavioral deterioration when the speaker's mouth is occluded
Reisinger, P.; Gillis, M.; Suess, N.; Vanthornhout, J.; Haider, C. L.; Hartmann, T.; Hauswald, A.; Schwarz, K.; Francart, T.; Weisz, N.
10.1101/2023.04.17.536524 — neuroscience — Posted on 2023-04-18
1842 Redefining normal breast cell populations using long noncoding RNAs
Bitar, M.; Rivera, I. S.; Pimentel de Almeida, I.; Shi, W.; Ferguson, K.; Beesley, J.; Lakhani, S.; Edwards, S.; French, J. D.
10.1101/2022.09.06.506112 — cell biology — Posted on 2023-04-18
1843 Inhibition of microtubule detyrosination by parthenolide facilitates functional CNS axon regeneration
Leibinger, M.; Zeitler, C.; Paulat, M.; Gobrecht, P.; Hilla, A.; Andreadaki, A.; Guthoff, R.; Fischer, D.
10.1101/2023.04.05.535722 — neuroscience — Posted on 2023-04-18
1848 The Drosophila MIC10 orthologue has a propensity to polymerize into cristae-shaping filaments
Stephan, T.; Stoldt, S.; Barbot, M.; Carney, T. D.; Lange, F.; Bates, M.; Bou Dib, P.; Shcherbata, H.; Meinecke, M.; Riedel, D.; Dennerlein, S.; Rehling, P.; Jakobs, S.
10.1101/2023.04.17.537183 — cell biology — Posted on 2023-04-17
1849 Focal adhesions are controlled by microtubules through local contractility regulation
Aureille, J.; Barnett, S.; Arnal, I.; Lafanechere, L.; Low, B. C.; Kanchanawong, P.; Mogilner, A.; Bershadsky, A.
10.1101/2023.04.17.535593 — cell biology — Posted on 2023-04-17
1850 Serum from pregnant donors induces human beta cell proliferation and insulin secretion
Sylvester-Armstrong, K. R.; Reeder, C. F.; Powell, A.; Becker, M. W.; Hagan, D. W.; Chen, J.; Mathews, C. E.; Wasserfall, C. H.; Atkinson, M. A.; Egerman, R.; Phelps, E. A.
10.1101/2023.04.17.537214 — cell biology — Posted on 2023-04-17
1852 Disulfiram Exerts anti-pulmonary Fibrosis Effect by Activating PGE2 Synthesis
Pei, X.; Zheng, F.; Li, Y.; Lin, Z.; Zhang, Y.; Han, X.; Feng, Y.; Li, F.; Yang, J.; Li, T.; Tian, Z.; Cao, K.; Ren, D.; Li, C.
10.1101/2023.04.16.537099 — cell biology — Posted on 2023-04-17
1853 Proteomic Investigation of Neural Stem Cell to Oligodendrocyte Precursor Cell Differentiation Reveals Phosphorylation-Dependent Dclk1 Processing
Hardt, R.; Dehghani, A.; Schoor, C.; Goedderz, M.; Cengiz Winter, N.; Ahmadi, S.; Sharma, R.; Schork, K.; Eisenacher, M.; Gieselmann, V.; Winter, D.
10.1101/2023.04.17.537129 — cell biology — Posted on 2023-04-17
1854 Aspergillus SUMOylation mutants have normal dynein function but exhibit chromatin bridges
Zhang, J.; Qiu, R.; Bieger, B. D.; Oakley, E.; Oakley, B. R.; Egan, M. J.; Xiang, X.
10.1101/2023.04.16.537086 — cell biology — Posted on 2023-04-18
1863 Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing
Hatanaka, F.; Suzuki, K.; Shojima, K.; Yu, J.; Takahashi, Y.; Sakamoto, A.; Prieto, J.; Shokhirev, M.; Esteban, C. R.; Nunez-Delicado, E.; Belmonte, J. C. I.
10.1101/2023.04.06.535786 — bioengineering — Posted on 2023-04-17
1867 Agricultural land use and lake morphology explain substantial variation in water quality across Canada
Sanchez Schacht, J. R.; MacKeigan, P. W.; Taranu, Z. E.; Huot, Y.; Gregory-Eaves, I.
10.1101/2022.08.29.505280 — ecology — Posted on 2023-04-17
1876 A spatiotemporal map of the aging mouse brain reveals white matter tracts as vulnerable foci
Hahn, O.; Foltz, A. G.; Atkins, M.; Kedir, B.; Moran-Losada, P.; Guldner, I. H.; Munson, C.; Kern, F.; Palovics, R.; Lu, N.; Kaur, A.; Hull, J.; Huguenard, J.; Groenke, S.; Lehallier, B.; Partridge, L.; Keller, A.; Wyss-Coray, T.
10.1101/2022.09.18.508419 — neuroscience — Posted on 2023-04-17
1877 mEMbrain: an interactive deep learning MATLAB tool for connectomic segmentation on commodity desktops
Pavarino, E. C.; Yang, E.; Dhanyasi, N.; Wang, M.; Bidel, F.; Lu, X.; Yang, F.; Park, C. F.; Bangalore Renuka, M.; Drescher, B.; Samuel, A. D. T.; Hochner, B.; Katz, P. S.; Zhen, M.; Lichtman, J. W.; Meirovitch, Y.
10.1101/2023.04.17.537196 — neuroscience — Posted on 2023-04-17
1879 Engineered autocrine signaling eliminates muscle cell FGF2 requirements for cultured meat production
Stout, A. J.; Zhang, X.; Letcher, S. M.; Rittenberg, M. L.; Shub, M.; Chai, K. M.; Kaul, M.; Kaplan, D. L.
10.1101/2023.04.17.537163 — bioengineering — Posted on 2023-04-17
1880 Cooperative breeding in a plural breeder: the vulturine guineafowl (Acryllium vulturinum)
Nyaguthii, B.; Dehnen, T.; Klarevas-IRby, J. A.; Papageorgiou, D.; Kosgey, J.; Farine, D. R.
10.1101/2022.11.23.517633 — animal behavior and cognition — Posted on 2023-04-17
1881 CD45 limits Natural Killer cell development from common lymphoid progenitors
Meza Guzman, L. G.; Hyland, C. D.; Bidgood, G. M.; Leong, E.; Shen, Z.; Goh, W.; Kratina, T.; Rautela, J.; Vince, J.; Nicholson, S.; Huntington, N.
10.1101/2023.04.17.537109 — cell biology — Posted on 2023-04-17
1882 Structure-function Analyses Reveal Key Molecular Determinants of HIV-1 CRF01_AE Resistance to the Entry Inhibitor Temsavir
Pazgier, M.; Prevost, J.; Chen, Y.; Zhou, F.; Tolbert, W. D.; Gasser, R.; Medjahed, H.; Gottumukkala, S.; Hessell, A.; Rao, V. B.; Pozharski, E.; Huang, R.; Motthies, D.; Finzi, A.
10.1101/2023.04.17.537181 — molecular biology — Posted on 2023-04-17
1886 PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma
Duchatel, R. J.; Jackson, E. R.; Parackal, S. G.; Sun, C.; Daniel, P.; Mannan, A.; Findlay, I. J.; Staudt, D.; Germon, Z. P.; Laternser, S.; Kiltschewskij, D.; Kearney, P. S.; Jamaluddin, M. F. B.; Douglas, A. M.; Beitaki, T.; Perrson, M.; Manning, E. E.; Murray, H. C.; Verrills, N. M.; Skerrett-Byrne, D. A.; Nixon, B.; Hua, S.; Valdes Mora, F.; Tsoli, M.; Ziegler, D. S.; Cairns, M. J.; Raabe, E. H.; Vitanza, N. A.; Koschmann, C.; Alvaro, F.; Dayas, C. V.; Tinkle, C.; Eisenstat, D.; Firestein, R.; Mueller, S.; Nazarian, J.; Cain, J.; Dun, M. D.
10.1101/2023.04.17.537256 — cancer biology — Posted on 2023-04-17
1887 Fluid-Structure Interactions of Peripheral Arteries Using a Coupled in silico and in vitro Approach
Schoenborn, S.; Lorenz, T.; Kuo, K.-C.; Fletcher, D. F.; Woodruff, M. A.; Pirola, S.; Allenby, M. C.
10.1101/2023.04.17.537257 — bioengineering — Posted on 2023-04-17
1888 The RNA helicase DDX1 associates with the nuclear RNA exosome and modulates R-loops
de Amorim, J. L.; Leung, S. W.; Haji-Seyed-Javadi, R.; Hou, Y.; Yu, D. S.; Ghalei, H.; Khoshnevis, S.; Yao, B.; Corbett, A. H.
10.1101/2023.04.17.537228 — biochemistry — Posted on 2023-04-17
1889 Histone divergence in Trypanosoma brucei results in unique alterations to nucleosome structure
Deak, G.; Wapenaar, H.; Sandoval, G.; Chen, R.; Taylor, M. R.; Burdett, H.; Watson, J. A.; Tuijtel, M. W.; Webb, S.; Wilson, M. D.
10.1101/2023.04.17.536592 — biochemistry — Posted on 2023-04-17
1890 The structure of a hibernating ribosome in a Lyme disease pathogen
Sharma, M. R.; Manjari, S. R.; Agrawal, E. K.; Keshavan, P.; Koripella, R. K.; Majumdar, S.; Marcinkiewicz, A. L.; Lin, Y.-P.; Agrawal, R. K.; Banavali, N. K.
10.1101/2023.04.16.537070 — biochemistry — Posted on 2023-04-17
1892 Ancient diversity in host-parasite interaction genes in a model parasitic nematode
Stevens, L.; Martinez-Ugalde, I.; King, E.; Wagah, M.; Absolon, D.; Bancroft, R.; Gonzalez de la Rosa, P.; Hall, J. L.; Kieninger, M.; Kloch, A.; Pelan, S.; Robertson, E.; Pedersen, A. B.; Abreu-Goodger, C.; Buck, A. H.; Blaxter, M.
10.1101/2023.04.17.535870 — evolutionary biology — Posted on 2023-04-17
1894 A chromatin-associated regulator of RNA Polymerase III assembly at tRNA genes revealed by locus-specific proteomics
van Breugel, M. E.; van Kruijsbergen, I.; Mittal, C.; Lieftink, C.; Brouwer, I.; van den Brand, T.; Kluin, R. J. C.; Menezes, R.; van Welsem, T.; Cortona, A. D.; Malik, M.; Beijersbergen, R.; Lenstra, T.; Verstrepen, K.; Pugh, F.; van Leeuwen, F.
10.1101/2023.04.17.534528 — molecular biology — Posted on 2023-04-17
1895 RNA editing of AZIN1 coding sites is catalyzed by ADAR1 p150 after splicing
Xing, Y.; Nakahama, T.; Wu, Y.; Inoue, M.; Kim, J. I.; Todo, H.; Shibuya, T.; Kato, Y.; Kawahara, Y.
10.1101/2023.04.17.537126 — molecular biology — Posted on 2023-04-17
1896 5-ASA can functionally replace Clostridia to prevent a post-antibiotic bloom of Candida albicans by maintaining epithelial hypoxia
Savage, H. P.; Bays, D. J.; Gonzalez, M. A. F.; Bejarano, E. J.; Nguyen, H.; Masson, H. L. P.; Carvalho, T. P.; Santos, R. L.; Thompson, G.; Bäumler, A. J.
10.1101/2023.04.17.537218 — microbiology — Posted on 2023-04-17
1899 Microbiome variability of mosquito lines is consistent over time and across environments
Accoti, A.; Quek, S.; Vulcan, J.; Cansado-Utrilla, C.; Anderson, E.; Alsing, J.; Narra, H. P.; Khanipov, K.; Hughes, G.; Dickson, L.
10.1101/2023.04.17.537119 — microbiology — Posted on 2023-04-17
1900 Trypanosoma cruzi VDU deubiquitinase mediates surface protein trafficking and infectivity
Souza-Melo, N.; Brito-Silva, N.; Malvezzi, A. M.; dos Santos, G. P.; Alcantara, L. M.; Alcantara, C. d. L.; Cunha e Silva, N. L. d.; Zoltner, M.; Field, M. C.; Schenkman, S.
10.1101/2023.04.17.537123 — microbiology — Posted on 2023-04-17
1901 Metabolic specialization drives reduced pathogenicity in Pseudomonas aeruginosa CF clinical isolates
Pedersen, B. H.; Simoes, F.; Pogrebnyakov, I.; Welch, M.; Johansen, H. K.; Molin, S.; La Rosa, R.
10.1101/2023.04.17.537125 — microbiology — Posted on 2023-04-17
1904 A weaponized phage suppresses competitors in historical and modern metapopulations of pathogenic bacteria
Backman, N.; Latorre, S. M.; Eads, L.; Som, S.; Belnap, D.; Manuel, A. M.; Burbano, H. A.; Karasov, T.
10.1101/2023.04.17.536465 — microbiology — Posted on 2023-04-17
1907 The ontogeny of individual specialization
Hertel, A. G.; Albrecht, J.; Selva, N.; Sergiel, A.; Hobson, K. A.; Janz, D. M.; Mulch, A.; Kindberg, J.; Hansen, J. E.; Frank, S. C.; Zedrosser, A.; Mueller, T.
10.1101/2023.04.17.537142 — ecology — Posted on 2023-04-17
1908 SARS-CoV-2 occurrence in white-tailed deer throughout their range in the conterminous United States
Bevins, S.; Chipman, R. B.; Beckerman, S. F.; Bergman, D. L.; Collins, D. T.; Deliberto, T. J.; Eckery, J. P.; Ellis, J. W.; Gosser, A. L.; Heale, J. D.; Klemm, J. M.; Lantz, K.; Linder, T. J.; Oswald, M.; Pleszewski, R.; Quintanal, C. A.; Ringenberg, J. M.; Weir, K. R.; Torchetti, M. K.; Lenoch, J. B.; Chandler, J. C.; Shriner, S. A.
10.1101/2023.04.14.533542 — ecology — Posted on 2023-04-17
1909 Human airway ex vivo models: new tools to study the airway epithelial cell response to SARS-CoV-2 infection
Assou, S.; Ahmed, E.; Morichon, L.; Nasri, A.; Foisset, F.; Bourdais, C.; Gros, N.; Wong, S.; Petit, A. F.; Vachier, I.; Muriaux, D.; Bourdin, A.; De Vos, J.
10.1101/2023.04.15.536998 — cell biology — Posted on 2023-04-17
1910 SARS-CoV-2 shifts transcription of host gene to increase Spike acylation and boost infectivity
Mesquita, F. S.; Abrami, L.; Bracq, L.; Panyain, N.; Mercier, V.; Kunz, B.; Chuat, A.; Carlevaro-Fita, J.; Trono, D.; van der Goot, F. G.
10.1101/2023.04.15.537011 — cell biology — Posted on 2023-04-17
1912 A role for myeloid miR-155 in regulating hypoxia induced seizures in neonatal C57BL/J6 mice
Dahiya, D.; Smith, J.; Strickland, T.; Morris, D.; Reschke, C.; Engel, T.; Henshall, D.; McCoy, C. E.; Dowling, J. K.
10.1101/2022.09.22.508924 — neuroscience — Posted on 2023-04-17
1914 mEMbrain: an interactive deep learning MATLAB tool for connectomic segmentation on commodity desktops
Pavarino, E. C.; Yang, E.; Dhanyasi, N.; Wang, M.; Bidel, F.; Lu, X.; Yang, F.; Park, C. F.; BR, M.; Drescher, B.; Samuel, A. D. T.; Hochner, B.; Katz, P. S.; Zhen, M.; Lichtman, J. W.; Meirovitch, Y.
10.1101/2023.04.17.537196 — neuroscience — Posted on 2023-04-17
1917 Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system
Datta, M. S.; Chen, Y.; Chauhan, S.; Zhang, J.; De La Cruz, E. D.; Gong, C.; Tomer, R.
10.1101/2023.04.12.536506 — neuroscience — Posted on 2023-04-17
1918 Human thalamic recordings reveal that epileptic spikes block sleep spindle production during non-rapid eye movement sleep
Wodeyar, A.; Chinappen, D.; Mylonas, D.; Baxter, B.; Manoach, D. S.; Eden, U. T.; Kramer, M. A.; Chu, C. J.
10.1101/2023.04.17.537191 — neuroscience — Posted on 2023-04-17
1921 PTEN knockout using retrogradely transported AAVs restores locomotor abilities in both acute and chronic spinal cord injury.
Stewart, A. N.; Kumari, R.; Bailey, W. M.; Glaser, E. P.; Hammers, G. V.; Wireman, O. H.; Gensel, J. C.
10.1101/2023.04.17.537179 — neuroscience — Posted on 2023-04-17
1925 Staying in control: characterising the mechanisms underlying cognitive control in high and low arousal states
Alameda, C.; Avancini, C.; Sanabria, D.; Bekinschtein, T. A.; Canales-Johnson, A.; Ciria, L. F.
10.1101/2023.04.17.536548 — neuroscience — Posted on 2023-04-17
1928 Dual spatio-temporal regulation of axon growth and microtubule dynamics by RhoA signaling pathways
Wojnacki, J.; Quassollo, G.; Bordenave, M. D.; Unsain, N.; Martinez, G. F.; Szalai, A. M.; Pertz, O.; Gundersen, G. G.; Bartolini, F.; Stefani, F. D.; Caceres, A.; Bisbal, M.
10.1101/2023.04.17.537156 — neuroscience — Posted on 2023-04-17
1929 Peripersonal tracking accuracy is limited by the speed and phase of locomotion
Davidson, M. J.; Keys, R.; Szekely, B.; MacNeilage, P. J.; Verstraten, F.; Alais, D.
10.1101/2023.04.17.537137 — neuroscience — Posted on 2023-04-17
1930 Neural extracellular matrix regulates visual sensory motor integration
Reinhard, J.; Mueller-Buehl, C.; Wiemann, S.; Roll, L.; Luft, V.; Shabani, H.; Rathbun, D. L.; Gan, L.; Kuo, C.-C.; Franzen, J.; Joachim, S. C.; Faissner, A.
10.1101/2023.04.17.537074 — neuroscience — Posted on 2023-04-17
1931 High-efficiency base editing for Stargardt disease in mice, non-human primates, and human retina tissue
Muller, A.; Sullivan, J.; Schwarzer, W.; Wang, M.; Park-Windhol, C.; Klingler, B.; Matsell, J.; Hostettler, S.; Galliker, P.; Duman, M.; Hou, Y.; Balmer, P.; Virag, T.; Barrera, L. A.; Xu, Q.; Magda, D. P.; Kilin, F.; Khadka, A.; Quinodoz, M.; Hasler, P. W.; Moreau, P.-H.; Fellmann, L.; Azoulay, T.; Cattaneo, M.; Picelli, S.; Grison, A.; Cowan, C. S.; Janeschitz-Kriegl, L.; Kusnyerik, A.; Renner, M.; Nagy, Z. Z.; Szabo, A.; Rivolta, C.; Scholl, H. P. N.; Bryson, D.; Ciaramella, G.; Roska, B.; György, B.
10.1101/2023.04.17.535579 — neuroscience — Posted on 2023-04-17
1936 On-demand low-frequency stimulation for seizure control: efficacy and behavioral implications
Paschen, E.; Kleis, P.; Vieira, D. M.; Heining, K.; Boehler, C.; Egert, U.; Haeussler, U.; Haas, C. A.
10.1101/2023.04.17.537172 — neuroscience — Posted on 2023-04-17
1937 Oncolytic vesicular stomatitis virus is safe and provides a survival benefit for dogs with naturally occurring osteosarcoma
Makielski, K. M.; Sarver, A. L.; Henson, M. S.; Stuebner, K. M.; Borgatti, A.; Suksanpaisan, L.; Preusser, C.; Tabaran, A.-F.; Cornax, I.; O'Sullivan, M. G.; Chehadeh, A.; Groschen, D.; Bergsrud, K.; Pracht, S.; Winter, A.; Mills, L. J.; Schwabenlander, M. D.; Wolfe, M.; Farrar, M. A.; Cutter, G. R.; Koopmeiners, J. S.; Russell, S. J.; Modiano, J. F.; Naik, S.
10.1101/2023.04.16.533664 — cancer biology — Posted on 2023-04-17
1938 FAO-supported OxPhos leukemic stem cells are sensitive to cold.
Griessinger, E.; Pereira-Martins, D.; Nebout, M.; Bosc, C.; Saland, E.; Boet, E.; Sahal, A.; Chiche, J.; Debayle, D.; Fleuriot, L.; Pruis, M.; De Mas, V.; Vergez, F.; Recher, C.; Huls, G.; Sarry, J.-E.; Schuringa, J. J.; Peyron, J.-F.
10.1101/2023.04.17.537132 — cancer biology — Posted on 2023-04-17
1941 Integrin beta4 promotes DNA damage drug resistance in triple-negative breast cancer via TNFAIP2/IQGAP1/Rac1
Fang, H.; Ren, W.; Cui, Q.; Liang, H.; Yang, C.; Liu, W.; Wang, X.; Liu, X.; Shi, Y.; Feng, J.; Chen, C.
10.1101/2023.04.17.537130 — cancer biology — Posted on 2023-04-17
1942 Neural correlates of object-extracted relative clause processing across English and Chinese
Dunagan, D.; Stanojevic, M.; Coavoux, M.; Zhang, S.; Bhattasali, S.; Li, J.; Brennan, J.; Hale, J. T.
10.1101/2022.09.12.507571 — neuroscience — Posted on 2023-04-17
1944 Longitudinal map of transcriptome changes in the Lyme pathogen Borrelia burgdorferi during tick-borne transmission
Sapiro, A. L.; Hayes, B. M.; Volk, R. F.; Zhang, J. Y.; Brooks, D. M.; Martyn, C.; Radkov, A.; Zhao, Z.; Kinnersley, M.; Secor, P. R.; Zaro, B. W.; Chou, S.
10.1101/2022.11.09.515847 — microbiology — Posted on 2023-04-17
1946 SHARPIN enhances ferroptosis in synovial sarcoma cells via NF-κB- and PRMT5-mediated PGC1α reduction
Tamiya, H.; Urushihara, N.; Shizuma, K.; Ogawa, H.; Nakai, S.; Wakamatsu, T.; Takenaka, S.; Kakunaga, S.
10.1101/2023.04.16.537061 — cancer biology — Posted on 2023-04-17
1947 Emerging variants of SARS-CoV-2 NSP10 highlight strong functional conservation of its binding to two non-structural proteins, NSP14 and NSP16
Wang, H.; Rizvi, S. R. A.; Dong, D.; Lou, J.; Wang, Q.; Sopipong, W.; Su, Y.; Najar, F.; Agarwal, P.; Kozielski, F. G.; Haider, S.
10.1101/2022.12.23.521761 — biophysics — Posted on 2023-04-17
1949 Scalable, flexible carbon fiber electrode thread arrays for three-dimensional spatial profiling of neurochemical activity in deep brain structures of rodents
Xia, M.; Agca, B. N.; Yoshida, T.; Choi, J.; Amjad, U.; Bose, K.; Keren, N.; Zukerman, S.; Cima, M. J.; Graybiel, A. M.; Schwerdt, H. N.
10.1101/2023.04.15.537033 — bioengineering — Posted on 2023-04-17
1951 How best to co-deploy insecticides to minimise selection for resistance.
Jones, S.; South, A.; Richardson, J.; Rees, S.; Sherrard-Smith, E.; Small, G.; Nimmo, D.; Hastings, I.
10.1101/2023.04.15.536881 — genetics — Posted on 2023-04-17
1952 Ecological genomics in the Northern krill uncovers loci for local adaptation across ocean basins
Unneberg, P.; Larsson, M.; Olsson, A.; Wallerman, O.; Petri, A.; Bunikis, I.; Vinnere Pettersson, O.; Papetti, C.; Gislason, A.; Glenner, H.; Cartes, J. E.; Blanco-Bercial, L.; Eriksen, E.; Meyer, B.; Wallberg, A.
10.1101/2023.04.15.537050 — evolutionary biology — Posted on 2023-04-17
1954 Bird communities in a selectively logged tropical montane forest are dominated by small, low-elevation species
Chanda, R.; Rai, S.; Tamang, B.; Munda, B.; Pradhan, D.; Rai, M.; Biswakarma, A.; Srinivasan, U.
10.1101/2023.04.15.537021 — ecology — Posted on 2023-04-17
1956 Multidimensional responses of ecological stability to eutrophication in grasslands
Chen, Q.; Wang, S.-P.; Borer, E. T.; Bakker, J. D.; Seabloom, E. W.; Harpole, W. S.; Eisenhauer, N.; Lekberg, Y.; Buckley, Y. M.; Catford, J. A.; Roscher, C.; Donohue, I.; Power, S. A.; Daleo, P.; Ebeling, A.; Knops, J. M. H.; Martina, J. P.; Eskelinen, A.; Morgan, J. W.; Risch, A. C.; Caldeira, M. C.; Bugalho, M. N.; Virtanen, R.; Barrio, I. C.; Niu, Y.; Jentsch, A.; Stevens, C. J.; Alberti, J.; Hautier, Y.
10.1101/2023.04.16.537045 — ecology — Posted on 2023-04-17
1958 EGFR+ lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth
Kuhlmann-Hogan, A.; Cordes, T.; Xu, Z.; Traina, K.; Robles-Oteiza, C.; Ayeni, D.; Kwong, E. M.; Levy, S.; Nobari, M.; Cheng, G. Z.; Shaw, R. J.; Leibel, S. L.; Metallo, C.; Politi, K.; Kaech, S. M.
10.1101/2023.04.15.536974 — immunology — Posted on 2023-04-17
1959 Systematic evaluation of intratumoral and peripheral BCR repertoires in three cancers
Krasik, S. V.; Bryushkova, E. A.; Sharonov, G. V.; Myalik, D. S.; Shurganova, E. V.; Komarov, D. V.; Shagina, I. A.; Shpudeiko, P. S.; Turchaninova, M. A.; Vakhitova, M. T.; Samoylenko, I. V.; Marinov, D. T.; Demidov, L. V.; Zagainov, V. E.; Chudakov, D. M.; Serebrovskaya, E. O.
10.1101/2023.04.16.537028 — immunology — Posted on 2023-04-17
1960 Modeling EEG Resting-State Brain Dynamics: A proof of concept for clinical studies
Kotz, S. A.; Astudillo, A.; Araya, D.; Dalla Bella, S.; Trujillo-Barreto, N.; El-Deredy, W.
10.1101/2023.04.15.536991 — neuroscience — Posted on 2023-04-17
1965 Nociception in chicken embryos, Part I: Analysis of cardiovascular responses to a mechanical noxious stimulus
Weiss, L.; Saller, A. M.; Werner, J.; Suess, S. C.; Reiser, J.; Kollmansperger, S.; Anders, M.; Fenzl, T.; Schusser, B.; Baumgartner, C.
10.1101/2023.04.14.536899 — physiology — Posted on 2023-04-17
1966 Incongruence between transcriptional and vascular pathophysiological cell states
Fernandez-Chacon, M.; Muhleder, S.; Regano, A.; Garcia-Ortega, L.; Torroja, C.; Lytvyn, M.; Sanchez-Munoz, M. S.; Casquero-Garcia, V.; Camafeita, E.; Vazquez, J.; Benguria, A.; Dopazo, A.; Sanchez-Cabo, F.; Carter, H.; Benedito, R.
10.1101/2023.04.16.537057 — physiology — Posted on 2023-04-17
1967 Spt5 interacts genetically with Myc and is limiting for brain tumor growth in Drosophila
Hofstetter, J.; Ogunleye, A.; Kutschke, A.; Buchholz, L. M.; Wolf, E.; Raabe, T.; Gallant, P.
10.1101/2023.04.14.536839 — cancer biology — Posted on 2023-04-17
1968 Molecular, metabolic and functional CD4 T cell paralysis impedes tumor control
Guo, M.; Abd-Rabbo, D.; Bertol, B.; Carew, M.; Lukhele, S.; Snell, L.; Xu, W.; Boukhaled, G.; Elsaesser, H.; Halaby, M. J.; Hirano, N.; McGaha, T.; Brooks, D.
10.1101/2023.04.15.536946 — cancer biology — Posted on 2023-04-17
1969 Somatic protospacer adjacent motifs are numerous and selectively targetable in cancers
Teh, S. S. K.; Bowland, K.; Bennett, A.; Halper-Stromberg, E.; Skaist, A.; Pallavajjala, A.; Tang, J.; Cai, F.; Macoretta, A.; Liang, H.; Wheelan, S.; Lin, M.-T.; Hruban, R. H.; Scharpf, R. B.; Roberts, N. J.; Eshleman, J. R.
10.1101/2023.04.15.537042 — cancer biology — Posted on 2023-04-17
1970 Advances on sparse Dynamic Scanning in Spectromicroscopy through Compressive Sensing
Kourousias, G.; Bille, F.; Ippoliti, M.; Guzzi, F.; Bonanni, V.; Gianoncelli, A.
10.1101/2023.04.14.536967 — biophysics — Posted on 2023-04-17
1972 GraphPart: Homology partitioning for biological sequence analysis
Teufel, F.; Gislason, M. H.; Almagro Armenteros, J. J.; Johansen, A. R.; Winther, O.; Nielsen, H.
10.1101/2023.04.14.536886 — bioinformatics — Posted on 2023-04-17
1973 Assisting and Accelerating NMR Assignment with Restrainted Structure Prediction
Liu, S.; Chu, H.; Xie, Y.; Wu, F.; Ni, N.; Wang, C.; Mu, F.; Wei, J.; Zhang, J.; Chen, M.; Li, J.; Yu, F.; Fu, H.; Wang, S.; Tian, C.; Wang, Z.; Gao, Y. Q.
10.1101/2023.04.14.536890 — bioinformatics — Posted on 2023-04-17
1976 PANGEA: A New Gene Set Enrichment Tool for Drosophila and Common Research Organisms
Hu, Y.; Comjean, A.; Attrill, H.; Antonazzo, G.; Thurmond, J.; Li, F.; Chao, T.; Mohr, S.; Brown, N. H.; Perrimon, N.
10.1101/2023.02.20.529262 — bioinformatics — Posted on 2023-04-17
1981 Migratory herbivorous waterfowl couple the seed wave and the green wave during spring migration
Xu, F.; Wu, W.; Wei, J.; Xin, Q.; Wielstra, B.; La Sorte, F. A.; Ma, Z.; Lei, G.; Lei, J.; Wu, W.; Yang, Y.; Gong, P.; Xu, B.; Si, Y.
10.1101/2023.04.14.536842 — ecology — Posted on 2023-04-17
1984 Auditory confounds can drive online effects of transcranial ultrasonic stimulation in humans
Kop, B. R.; Shamli Oghli, Y.; Grippe, T. C.; Nandi, T.; Lefkes, J.; Meijer, S. W.; Farboud, S.; Engels, M.; Hamani, M.; Null, M.; Radetz, A.; Hassan, U.; Darmani, G.; Chetverikov, A.; den Ouden, H. E. M.; Bergmann, T. O.; Chen, R.; Verhagen, L.
10.1101/2023.02.22.527901 — neuroscience — Posted on 2023-04-17
1985 Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes
Paudel, B. B.; Tan, S.-F.; Fox, T. E.; Ung, J.; Shaw, J.; Dunton, W.; Lee, I.; Sharma, A.; Viny, A. D.; Barth, B. M.; Tallman, M. S.; Cabot, M.; Garrett-Bakelman, F. E.; Levine, R. L.; Kester, M.; Claxton, D.; Feith, D. J.; Janes, K. A.; Loughran, T. P.
10.1101/2023.04.13.536805 — systems biology — Posted on 2023-04-17
1988 BRG1 generates subnucleosomes that expand OCT4 binding and function beyond DNA motifs at enhancers
Nocente, M. C.; Mesihovic, A.; Drouineau, E.; Albawardi, W.; Dulary, C.; Ribierre, F.; Picaud, H.; Alibert, O.; Acker, J.; Aude, J.-C.; Gilbert, N.; Ochsenbein, F.; Chantalat, S.; Gerard, M.
10.1101/2022.09.15.507958 — genomics — Posted on 2023-04-17
1990 An Aging-Susceptible Circadian Rhythm Controls Cutaneous Antiviral Immunity
Kirchner, S.; Lei, V.; Kim, P.; Patel, M.; Shannon, J.; Corcoran, D.; Hughes, D.; Waters, D.; Dzirasa, K.; Erdmann, D.; Coers, J.; Zhang, J.
10.1101/2023.04.14.536934 — immunology — Posted on 2023-04-17
1992 Nociception in chicken embryos, Part II: Embryonal development of electroencephalic neuronal activity in ovo as a prerequisite for nociception
Kollmansperger, S.; Anders, M.; Werner, J.; Saller, A. M.; Weiss, L.; Suess, S. C.; Reiser, J.; Schneider, G.; Schusser, B.; Baumgartner, C.; Fenzl, T.
10.1101/2023.04.14.536947 — neuroscience — Posted on 2023-04-17
1993 Discovery and Validation of Novel LonP1 and Proteasome Inhibitor in IDH1-R132H Malignant Astrocytoma Models
Douglas, C. R.; Lomeli, N.; Lepe, J.; Di, K.; Nandwana, N. K.; Vu, T.; Pham, J.; Kenney, M. C.; Das, B.; Bota, D.
10.1101/2023.04.13.536816 — cancer biology — Posted on 2023-04-17
1996 Charting spatial ligand-target activity using Renoir
Rao, N.; Pai, R.; Mishra, A.; Ginhoux, F.; Chan, J.; Sharma, A.; Zafar, H.
10.1101/2023.04.14.536833 — bioinformatics — Posted on 2023-04-17
1998 Mapping lineage-traced cells across time points with moslin
Lange, M.; Piran, Z.; Klein, M.; Spanjaard, B.; Klein, D.; Junker, J. P.; Theis, F. J.; Nitzan, M.
10.1101/2023.04.14.536867 — bioinformatics — Posted on 2023-04-17
1999 SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state
Sebastian-Perez, R.; Nakagawa, S.; Tu, X.; Aranda, S.; Pesaresi, M.; Gomez-Garcia, P. A.; Alcoverro-Bertran, M.; Gomez-Vazquez, J. L.; Carnevali, D.; Borras, E.; Sabido, E.; Martin, L.; Nissim-Rafinia, M.; Meshorer, E.; Neguembor, M. V.; Di Croce, L.; Cosma, M. P.
10.1101/2023.04.15.537018 — developmental biology — Posted on 2023-04-17
2000 A transient dermal niche and dual epidermal programs underlie sweat gland development
Dingwall, H. L.; Tomizawa, R. R.; Aharoni, A.; Hu, P.; Qiu, Q.; Kokalari, B.; Martinez, S. M.; Donahue, J. C.; Aldea, D.; Mendoza, M.; Glass, I. A.; Birth Defects Research Laboratory, ; Wu, H.; Kamberov, Y. G.
10.1101/2023.04.15.537037 — developmental biology — Posted on 2023-04-17
2001 The lncRNA Malat1 Inhibits miR-15/16 to Enhance Cytotoxic T Cell Activation and Memory Cell Formation
Wheeler, B. D.; Gagnon, J. D.; Zhu, W. S.; Munoz-Sandoval, P.; Wong, S. K.; Simeonov, D. S.; Li, Z.; Debarge, R.; Spitzer, M.; Marson, A.; Ansel, K. M.
10.1101/2023.04.14.536843 — immunology — Posted on 2023-04-17
2006 Characterizing the monomer-dimer equilibrium of UbcH8/Ube2L6: A combined SAXS and NMR study
Kahraman, K.; Robson, S. A.; Gocenler, O.; Yenici, C. M.; Tozkoparan, C. D.; Klein, J. M.; Haas, A. L.; Ziarek, J. J.; Dag, C.
10.1101/2023.04.13.536743 — biochemistry — Posted on 2023-04-17
2007 Initiation of fibronectin fibrillogenesis is an enzyme-dependent process
Melamed, S.; Zaffryar-Eilot, S.; Nadjar-Boger, E.; Aviram, R.; Zhao, H.; Yaseen-Badarne, W.; Kalev-Altman, R.; Sela-Donenfeld, D.; Lewinson, O.; Astrof, S.; Hasson, P.; Wolfenson, H.
10.1101/2022.11.16.516843 — cell biology — Posted on 2023-04-17
2008 DEK oncoprotein participates in heterochromatin replication via SUMO-dependent nuclear bodies
Pierzynska-Mach, A.; Czada, C.; Vogel, C.; Gwosch, E.; Osswald, X.; Bartoschek, D.; Diaspro, A.; Kappes, F.; Ferrando-May, E.
10.1101/2023.03.09.529154 — cell biology — Posted on 2023-04-17
2012 Spatial architecture of high-grade glioma reveals tumor heterogeneity within distinct domains
Moffet, J. J. D.; Fatunla, O. E.; Freytag, L.; Jones, J. J.; Roberts-Thomson, S. J.; Pavenko, A.; Scoville, D. K.; Zhang, L.; Liang, Y.; Morokoff, A. P.; Whittle, J. R.; Freytag, S.; Best, S. A.
10.1101/2023.03.13.531204 — cancer biology — Posted on 2023-04-16
2014 Efficient and Robust Search of Microbial Genomes via Phylogenetic Compression
Brinda, K.; Lima, L.; Pignotti, S.; Quinones-Olvera, N.; Salikhov, K.; Chikhi, R.; Kucherov, G.; Iqbal, Z.; Baym, M.
10.1101/2023.04.15.536996 — bioinformatics — Posted on 2023-04-16
2018 A data-driven approach for enhancing forest productivity by accounting for indirect genetic effects
Ferreira, F. M.; Chaves, S. F.; Bhering, L. L.; Alves, R. S.; Takahashi, E. K.; Resende, M. D.; Souza, J. E.; Gezan, S. A.; Viana, J. M. S.; Fernandes, S. B.; Dias, K. O. G.
10.1101/2023.04.14.536978 — genetics — Posted on 2023-04-16
2019 Defining the mechanisms of action and resistance to the anti-PD-1+LAG-3 and anti-PD-1+CTLA-4 combinations in melanoma flank and brain models
Phadke, M.; Li, J.; Chen, Z.; Rodriguez, P. C.; Mandula, J. K.; Karapetyan, L.; Forsyth, P. A.; Chen, A.; Smalley, K. S.
10.1101/2023.04.14.536907 — immunology — Posted on 2023-04-16
2020 An Aging-Susceptible Circadian Rhythm Controls Cutaneous Antiviral Immunity
Kirchner, S.; Lei, V.; Kim, P.; Patel, M.; Shannon, J.; Corcoran, D.; Hughes, D.; Waters, D.; Dzirasa, K.; Coers, J.; Zhang, J.
10.1101/2023.04.14.536934 — immunology — Posted on 2023-04-16
2021 Type I IFN expression is inhibited during cell division by CDK4/6
Sumner, R. P.; Ellis, A.; Lant, S.; Ashby, H.; Towers, G. J.; Maluquer de Motes, C.
10.1101/2023.04.15.537049 — immunology — Posted on 2023-04-16
2022 Tuning Minimum-Norm regularization parameters for optimal MEG connectivity estimation
Vallarino, E.; Hincapie, A. S.; Jerbi, K.; Leahyf, R.; Pascarella, A.; Sorrentino, A.; Sommariva, S.
10.1101/2023.04.15.537017 — neuroscience — Posted on 2023-04-16
2026 A rapid ELISA platform with no sample preparation requirement
Maganzini, N.; Reschke, A.; Cartwright, A.; Gidi, Y.; Thompson, I. A. P.; Hariri, A. A.; Dory, C.; Rosenberg-Hasson, Y.; Pan, J.; Eisenstein, M.; Cornell, T.; Soh, H. T.
10.1101/2023.04.14.536923 — bioengineering — Posted on 2023-04-16
2030 Information storage across a microbial community using universal RNA memory
Kalvapalle, P. B.; Staubus, A.; Dysart, M. J.; Gambill, L.; Reyes Gamas, K.; Chieh Lu, L.; Silberg, J. J.; Stadler, L. B.; Chappell, J.
10.1101/2023.04.16.536800 — synthetic biology — Posted on 2023-04-16
2031 ENOD93 interacts with cytochrome c oxidase altering respiratory ATP production and root growth in plants
Lee, C. P.; Le, X. H.; Gawryluk, R. M.; Casaretto, J. A.; Rothstein, S. J.; Millar, A. H.
10.1101/2023.04.15.535782 — plant biology — Posted on 2023-04-16
2033 Four additional natural 7-deazaguanine derivatives in phages and how to make them
Cui, L.; Balamkundu, S.; Liu, C. F.; Ye, H.; Hourihan, J.; Rausch, A.; Hauss, C.; Nilsson, E.; Hötzinger, M.; Holmfeldt, K.; Zhang, W.; Martinez-Alvarez, L.; Peng, X.; Tremblay, D.; Moinau, S.; Solonenko, N.; Sullivan, M. B.; Lee, Y.-J.; Mulholland, A.; Weigele, P.; de Crecy-Lagard, V.; Dedon, P. C.; Hutinet, G.
10.1101/2023.04.13.536721 — genomics — Posted on 2023-04-16
2035 Marine transmissible cancer navigates urbanised waters, threatening to spillover
Hammel, M.; Touchard, F.; Burioli, E. A. V.; Paradis, L.; Cerqueira, F.; Chailler, E.; Bernard, I.; Cochet, H.; Simon, A.; Thomas, F.; Destoumieux-Garzon, D.; Charriere, G. M.; Bierne, N.
10.1101/2023.04.14.536605 — ecology — Posted on 2023-04-16
2036 Sex biased human thymic architecture guides T cell development through spatially defined niches
Stankiewicz, L. N.; Rossi, F. M.; Zandstra, P. W.; Salim, K.; Flaschner, E. A.; Wang, Y. X.; Edgar, J. M.; Lin, B. Z.; Bingham, G. C.; Major, M. C.; Jones, R. D.; Blau, H.; Rideout, E.; Levings, M. K.
10.1101/2023.04.13.536804 — immunology — Posted on 2023-04-16
2037 Acid enhances salt taste by activating the epithelial sodium channel
Collier, D. M.; Peterson, Z. J.; Ryan, A. J.; Williford, N. N.; Benson, C. J.; Snyder, P. M.
10.1101/2023.04.14.536795 — physiology — Posted on 2023-04-16
2038 Data-Driven Modelling of Gene Expression States in Breast Cancer and their Prediction from Routine Whole Slide Images
Dawood, M.; Eastwood, M.; Jahanifar, M.; Young, L.; Ben-Hur, A.; Branson, K.; Jones, L.; Rajpoot, N.; Minhas, F. u. A. A.
10.1101/2023.04.14.536756 — pathology — Posted on 2023-04-16
2040 Fibronectin, DHPS and SLC3A2 Signaling Cooperate to Control Tumor Spheroid Growth, Subcellular eIF5A1/2 Distribution and CDK4/6 Inhibitor Resistance
Geller, C.; Maddela, J.; Tuplano, R.; Runa, F.; Adamian, Y.; Guth, R.; Soto, G. O.; Tomaneng, L.; Cantor, J.; Kelber, J. A.
10.1101/2023.04.13.536765 — cancer biology — Posted on 2023-04-16
2041 Electrostatic interactions control the adsorption of extracellular vesicles onto supported lipid bilayers
Ridolfi, A.; Cardellini, J.; Gashi, F.; van Herwijnen, M. J. C.; Trulsson, M.; Campos-Teran, J.; Wauben, M. H. M.; Berti, D.; Nylander, T.; Stenhammar, J.
10.1101/2023.04.14.536633 — biophysics — Posted on 2023-04-16
2044 Biomechanics Characterization of Autonomic and Somatic Nerves by High Dynamic Closed-Loop MEMS force sensing
Gonzalez-Gonzalez, M. A.; Alemansour, H.; Maroufi, M.; Coskun, M. B.; Lloyd, D.; Moheimani, S. O. R.; Romero-Ortega, M. I.
10.1101/2023.04.13.536752 — bioengineering — Posted on 2023-04-16
2045 Characterizing the monomer-dimer equilibrium of UbcH8/Ube2L6: A combined SAXS and NMR study
Kahraman, K.; Robson, S. A.; Gocenler, O.; Tozkoparan, C. D.; Klein, J. M.; Yenici, C. M.; Haas, A. L.; Ziarek, J. J.; Dag, C.
10.1101/2023.04.13.536743 — biochemistry — Posted on 2023-04-16
2048 Disruption of desmoplastic stroma overcomes restrictions to T cell extravasation, immune exclusion and immunosuppression in solid tumors
Xiao, Z.; Lu, Z.; Tood, L.; Huang, L.; Kopp, M.; Huang, L.; Zhong, W.; Li, Y.; Guo, W.; Schollor, J.; June, C. H.; Albelda, S. M.; Pure, E.
10.1101/2023.04.13.536777 — immunology — Posted on 2023-04-16
2050 Complex spikes perturb movements, revealing the sensorimotor map of Purkinje cells
Muller, S. Z.; Pi, J. S.; Hage, P.; Fakharian, M. A.; Sedaghat-Nejad, E.; Shadmehr, R.
10.1101/2023.04.16.537034 — neuroscience — Posted on 2023-04-16
2051 Integrative identification of non-coding regulatory regions driving metastatic prostate cancer
Woo, B. J.; Moussavi-Baygi, R.; Karner, H.; Karimzadeh, M.; Garcia, K.; Joshi, T.; Yin, K.; Navickas, A.; Gilbert, L. A.; Wang, B.; Asgharian, H.; Feng, F. Y.; Goodarzi, H.
10.1101/2023.04.14.535921 — cancer biology — Posted on 2023-04-16
2054 A Machine Learning-optimized system for on demand, pulsatile, photo- and chemo-therapeutic treatment using near-infrared responsive MoS2-based microparticles in a breast cancer model
Kanelli, M.; Bardhan, N. M.; Sarmadi, M.; Alsaiari, S.; Rothwell, W. T.; Pardeshi, A. R.; De Fiesta, D. C.; Mak, H.; Spanoudaki, V.; Henning, N.; Han, J.; Belcher, A.; Langer, R. S.; Jaklenec, A.
10.1101/2023.04.16.536750 — bioengineering — Posted on 2023-04-16
2055 Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome
Singh, V.; Moran, J. C.; Itoh, Y.; Soto, I. C.; Fontanesi, F.; Couvillion, M.; Huynen, M.; Churchman, S.; Barrientos, A.; Amunts, A.
10.1101/2022.06.20.496763 — biochemistry — Posted on 2023-04-16
2056 A Draft Reference Genome for Hirudo verbana, the Medicinal Leech
Paulsen, R. T.; Agany, D. D. M.; Petersen, J.; Davis, C. M.; Ehli, E. A.; Gnimpieba, E.; Burrell, B. D.
10.1101/2020.12.08.416024 — genomics — Posted on 2023-04-16
2057 Complex spikes perturb movements, revealing the sensorimotor map of Purkinje cells
Muller, S. Z.; Pi, J. S.; Hage, P.; Fakharian, M. A.; Sedaghat-Nejad, E.; Shadmehr, R.
10.1101/2023.04.16.537034 — neuroscience — Posted on 2023-04-16
2060 Driving and suppressing the human language network using large language models
Tuckute, G.; Sathe, A.; Srikant, S.; Taliaferro, M.; Wang, M.; Schrimpf, M.; Kay, K.; Fedorenko, E.
10.1101/2023.04.16.537080 — neuroscience — Posted on 2023-04-16
2062 Gap junctions in Turing-type periodic feather pattern formation
Tseng, C.-C.; Woolley, T. E.; Jiang, T.-X.; Wu, P.; Maini, P. K.; Widelitz, R. B.; Chuong, C.-M.
10.1101/2023.04.15.537019 — developmental biology — Posted on 2023-04-16
2063 Xenopus Ssbp2 is required for embryonic pronephros morphogenesis and terminal differentiation
Cervino, A. S.; Collodel, M. G.; Lopez, I. A.; Hochbaum, D.; Hukriede, N. A.; Cirio, M. C.
10.1101/2023.04.15.537039 — developmental biology — Posted on 2023-04-16
2065 Synergistic Screening of Peptide-Based Biotechnological Drug Candidates for Neurodegenerative Diseases using Yeast Display and Phage Display
Ozcelik, C. E.; Begli, O.; Hincer, A.; Ahan, R. E.; Oguz, O.; Kesici, M. S.; Ozcubukcu, S.; Kasirga, T. S.; Seker, U. O. S.
10.1101/2023.04.14.536742 — neuroscience — Posted on 2023-04-16
2067 A neural basis of choking under pressure
Smoulder, A. L.; Marino, P. J.; Oby, E. R.; Snyder, S. E.; Miyata, H.; Pavlovsky, N. P.; Bishop, W. E.; Yu, B. M.; Chase, S. M.; Batista, A. P.
10.1101/2023.04.16.537007 — neuroscience — Posted on 2023-04-16
2068 LSD microdosing attenuates the impact of temporal priors in time perception.
Sadibolova, R.; Murray-Lawson, C.; Family, N.; Williams, L. T. J.; Luke, D. P.; Terhune, D. B.
10.1101/2023.04.14.536983 — neuroscience — Posted on 2023-04-16
2069 Multipotent Progenitors Instruct Ontogeny of the Superior Colliculus
Cheung, G.; Pauler, F. M.; Koppensteiner, P.; Krausgruber, T.; Streicher, C.; Schrammel, M.; Gutmann-Oezgen, N.; Ivec, A. E.; Bock, C.; Shigemoto, R.; Hippenmeyer, S.
10.1101/2023.04.16.537059 — neuroscience — Posted on 2023-04-16
2074 6mA-Sniper: Quantifying 6mA Sites in Eukaryotes at Single-Nucleotide Resolution
Zhang, J.; Peng, Q.; Ma, C.; Wang, J.; Xiao, C.; Li, T.; Liu, X.; Zhou, L.; Zhou, W.-Z.; Ding, W.; An, N. A.; Zhang, L.; Liu, Y.; Li, C.-Y.
10.1101/2023.03.16.530559 — genomics — Posted on 2023-04-16
2076 Mechanism of glucocorticoid receptor activation regulated expression of thrombospondin-1
Zhang, G.-X.; Wang, Y.-Y.; Song, Y.-Y.; Jiang, W.-Y.; Zhang, H.-T.; Chen, J.-W.; Murao, K.; Sun, W.-P.
10.1101/2023.04.13.536820 — pathology — Posted on 2023-04-16
2078 Systematic mining and functional analysis of factors regulating wheat spike development for breeding selection
Lin, X.; Xu, Y.; Wang, D.; Yang, Y.; Zhang, X.; Bie, X.; Wang, H.; Jiang, J.; Chen, Z.; Gui, L.; Ding, Y.; Che, Y.; Li, A.; Zhang, X.; Lu, F.; Zhao, X.; Zhang, X.; Fu, X.; Xiao, J.
10.1101/2022.11.11.516122 — plant biology — Posted on 2023-04-16
2079 Learning induces unique transcriptional landscapes in the auditory cortex
Graham, G.-E.; Chimenti, M. S.; Knudtson, K.; Grenard, D. N.; Co, L.; Sumner, M.; Tchou, T.; Bieszczad, K. M.
10.1101/2023.04.15.536914 — neuroscience — Posted on 2023-04-15
2081 Mll1 pioneers histone H3K4me3 deposition and promotes formation of CD8+ T stem cell memory
Getzler, A. J.; Frederick, M. A.; Milner, J. J.; Venables, T.; Diao, H.; Toma, C.; Nagaraja, S.; Albao, D.; Belanger, S.; Tsuda, S. M.; Kim, J.; Crotty, S.; Goldrath, A.; Pipkin, M. E.
10.1101/2023.01.18.524461 — immunology — Posted on 2023-04-15
2082 β1 integrin signaling governs necroptosis via the chromatin remodeling factor CHD4
Sun, Z.; Cernilogar, F. M.; Horvatic, H.; Yeroslaviz, A.; Abdullah, Z.; Schotta, G.; Hornung, V.
10.1101/2023.04.14.536920 — immunology — Posted on 2023-04-15
2084 Structural and mechanistic insights into the MCM8/9 helicase complex
Weng, Z.; Zheng, J.; Zhou, Y.; Lu, Z.; Wu, Y.; Xu, D.; Li, H.; Liang, H.; Liu, Y.
10.1101/2022.01.26.477944 — biophysics — Posted on 2023-04-15
2086 Why the brown ghost chirps at night
Oboti, L.; Pedraja, F.; Ritter, M.; Lohse, M.; Klette, L.; Krahe, R.
10.1101/2022.12.29.522225 — animal behavior and cognition — Posted on 2023-04-15
2088 Chromatin structure and context-dependent sequence features control prime editing efficiency
Kim, S.; Yuan, J. B.; Woods, W. S.; Newton, D. A.; Perez-Pinera, P.; Song, J. S.
10.1101/2023.04.15.536944 — genomics — Posted on 2023-04-15
2090 Asymmetrical gene flow between coastal and inland dunes in a threatened digger wasp
Batsleer, F.; Gallin, M.; Delafonteyne, M.; Dekeukeleire, D.; T'Jollyn, F.; Vantieghem, P.; Vanden Broeck, A.; Mergeay, J.; Maes, D.; Bonte, D.
10.1101/2022.09.20.508247 — ecology — Posted on 2023-04-15
2092 Sterile Soil as Prebiotics Mitigate Intergenerational Loss of Gut Microbial Diversity and Anxiety-Like Behavior Induced by Antibiotics in mice
Li, N.; Xiao, X.; Zhang, H.; Bai, Z.; Li, M.; Sun, J.; Dong, Y.; Zhu, W.; Sun, X.; Fei, Z.; Xiao, P.; Gao, Y.; Zhou, D.
10.1101/2023.04.15.536315 — microbiology — Posted on 2023-04-15
2094 Plasma cells are formed in waning germinal centers via an affinity-independent process
Sutton, H. J.; Parker, B. J.; Lofgren, M.; Dacon, C.; Chatterjee, D.; Gao, X.; Kelly, H. G.; Seder, R. A.; Tan, J.; Idris, A. H.; Neeman, T.; Cockburn, I. A.
10.1101/2023.04.13.536825 — immunology — Posted on 2023-04-15
2095 Long timescale anti-directional rotation in Drosophila optomotor behavior
Mano, O.; Choi, M.; Tanaka, R.; Creamer, M. S.; Castelo Branco Matos, N.; Shomar, J.; Badwan, B. A.; Clandinin, T. R.; Clark, D. A.
10.1101/2023.01.06.523055 — neuroscience — Posted on 2023-04-15
2098 Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity
Chitraju, C.; Fischer, A. W.; Ambaw, Y. A.; Wang, K.; Yuan, B.; Hui, S. T.; Walther, T. C.; Farese, R.
10.1101/2022.05.05.490833 — physiology — Posted on 2023-04-15
2099 RNF43 mutations facilitate colorectal cancer metastasis via formation of a tumour-intrinsic niche
Bugter, J. M.; El Bouazzaoui, L.; Kucukkose, E.; Hong, Y.; Sprangers, J.; Jordens, I.; Fenderico, N.; Gonzalez, D. M.; van Boxtel, R.; Suijkerbuijk, S. J. E.; Tejpar, S.; Snippert, H. J. G.; Kranenburg, O.; Maurice, M. M.
10.1101/2022.12.22.521159 — cancer biology — Posted on 2023-04-15
2105 Structural Organization of the Cell Wall of Halophilic Fungi
Fernando, L. D.; Perez-Llano, Y.; Dickwella Widanage, M. C.; Martinez-Avila, L.; Lipton, A. S.; Gunde-Cimerman, N.; Latge, J.-P.; Batista-Garcia, R. A.; Wang, T.
10.1101/2023.04.15.537024 — biophysics — Posted on 2023-04-15
2109 Deep Neural Networks Predict MHC-I Epitope Presentation and Transfer Learn Neoepitope Immunogenicity
Albert, B. A.; Yang, Y.; Shao, X. M.; Singh, D.; Smith, K. N.; Anagnostou, V.; Karchin, R.
10.1101/2022.08.29.505690 — bioinformatics — Posted on 2023-04-15
2112 Structure and function of a hexameric cyanophycin synthetase 2
Markus, L. M. D.; Sharon, I.; Munro, K.; Grogg, M.; Hilvert, D.; Strauss, M.; Schmeing, M.
10.1101/2023.04.15.537035 — biochemistry — Posted on 2023-04-15
2114 A novel and highly specific Forssman antigen-binding protein from sheep polyomavirus
Rustmeier, N. H.; Silva, L. M.; Di Maio, A.; Müller, J. C.; Herrmann, A.; Feizi, T.; Liu, Y.; Stehle, T.
10.1101/2023.04.10.536218 — biochemistry — Posted on 2023-04-15
2115 High-resolution genome-wide mapping of chromosome-arm-scale truncations induced by CRISPR-Cas9 editing
Lazar, N. H.; Celik, S.; Chen, L.; Fay, M.; Irish, J. C.; Jensen, J.; Tillinghast, C. A.; Urbanik, J.; Bone, W. P.; Roberts, G. H. L.; Gibson, C. C.; Haque, I. S.
10.1101/2023.04.15.537038 — genomics — Posted on 2023-04-15
2116 Novel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and is required for male fertility and flagellum function.
Dacheux, D.; Martinez, G.; Broster Reix, C. E.; Beurois, J.; Tounkara, M.; Dupuy, J.-W.; Robinson, D. R.; Loeuillet, C.; Lambert, E.; Wehbe, Z.; Amiri-Yekta, A.; Daneshipour, A.; Hosseini, S.-H.; Zouari, R.; Fourati Ben Mustapha, S.; Halouani, L.; Jiang, X.; Shen, Y.; Liu, C.; Thierry-Mieg, N.; Septier, A.; Bidart, M.; Satre, V.; Cazin, C.; Kherraf, Z.-E.; Arnoult, C.; Ray, P. F.; Toure, A.; Bonhivers, M.; Coutton, C.
10.1101/2023.03.07.531490 — genetics — Posted on 2023-04-15
2118 A step towards measuring connectivity in the deep-sea: elemental fingerprints of mollusk larval shells discriminate hydrothermal sites
Mouchi, V.; Pecheyran, C.; Claverie, F.; Cathalot, C.; Matabos, M.; Germain, Y.; Rouxel, O.; Jollivet, D.; Broquet, T.; Comtet, T.
10.1101/2023.01.03.522618 — ecology — Posted on 2023-04-15
2121 PARK15/FBXO7 is dispensable for PINK1/Parkin-dependent mitophagy in iNeuron and HeLa cell systems
Kraus, F.; Goodall, E. A.; Smith, I. R.; Jiang, Y.; Paoli, J. C.; Adolf, F.; Zhang, J.; Paulo, J. A.; Schulman, B. A.; Harper, J. W.
10.1101/2022.11.02.514817 — cell biology — Posted on 2023-04-15
2122 Longitudinal Survey of Astrovirus infection in different bat species in Zimbabwe: Evidence of high genetic Astrovirus diversity
Chidoti, V.; De Nys, H.; Abdi, M.; Mashura, G.; Pinarello, V.; Chiweshe, N.; Matope, G.; Guerrini, L.; Pfulenyi, D.; Cappelle, J.; Mwandiringana, E.; Misse, D.; Elizabeth, G.; Bourgarel, M.; Florian, L.
10.1101/2023.04.14.536987 — molecular biology — Posted on 2023-04-15
2123 ResFinderFG v2.0: a database of antibiotic resistance genes obtained by functional metagenomics
Gschwind, R.; Ugarcina Perovic, S.; Weiss, M.; Petitjean, M.; Lao, J.; Coelho, L. P.; Ruppe, E.
10.1101/2022.10.19.512667 — microbiology — Posted on 2023-04-15
2124 Initiation of neutralizing antibody response probed using synthetic virus-like structures
Wholey, W.-Y.; Meyer, A. R.; Yoda, S.-T.; Chackerian, B.; Zikherman, J.; Cheng, W.
10.1101/2023.02.20.529089 — microbiology — Posted on 2023-04-15
2129 Identification of merozoite secreted repertoire and immuno-pharmacological inhibition of a novel host-parasite interaction to block malarial infection
Singh, N.; Munjal, A.; Kunari, G.; Kaushik, S.; Kahlon, A. K.; Gupta, S.; Chaurasiya, A.; Anam, Z.-e.-; Maurya, M. k.; Srivastava, P.; Singhal, J.; Marothia, M.; Joshi, P.; Jain, R.; Rex, D. A. B.; T S, K. P.; Mundae, M.; Malhotra, P.; Ranganathan, A.; Singh, S.
10.1101/2023.04.15.537002 — microbiology — Posted on 2023-04-15
2130 Dietary environmental factors shape the immune defence against infection with Cryptosporidium
Maradana, M. R.; Marzook, N. B.; Diaz Perez, O.; Mkandawire, T.; Diny, N. L.; Li, Y.; Liebert, A.; Shah, K.; Tolaini, M.; Kvac, M.; Stockinger, B.; Sateriale, A.
10.1101/2023.03.30.534739 — immunology — Posted on 2023-04-15
2136 An unsupervised learning approach uncovers divergent mesenchymal-like gene expression programs across human neuroblastoma tumors, preclinical models, and chemotherapy-exposed tumors.
Chapple, R. H.; Liu, X.; Natarajan, S.; Alexander, M. I. M.; Kim, Y.; Patel, A. G.; LaFlamme, C. W.; Pan, M.; Wright, W. C.; Lee, H.-M.; Zhang, Y.; Lu, M.; Koo, S. C.; Long, C.; Harper, J.; Savage, C.; Johnson, M. D.; Confer, T.; Akers, W. J.; Dyer, M. A.; Sheppard, H.; Easton, J.; Geeleher, P.
10.1101/2023.04.13.536639 — cancer biology — Posted on 2023-04-15
2138 Netrin-1 directs vascular patterning and maturity in the developing kidney
Honeycutt, S. E.; N'Guetta, P.-E. Y.; Hardesty, D. M.; Xiong, Y.; Cooper, S. L.; O'Brien, L. L.
10.1101/2023.04.14.536975 — developmental biology — Posted on 2023-04-15
2142 Natural Forgetting is Modulated by Experience
O'Leary, J. D.; Bruckner, R.; Autore, L.; Ryan, T. J.
10.1101/2023.04.15.537013 — neuroscience — Posted on 2023-04-15
2145 Visualization of trans homophilic interaction of clustered protocadherin in neurons
Hoshino, N.; Kanadome, T.; Itoh, M.; Kaneko, R.; Inoue, Y. U.; Inoue, T.; Hirabayashi, T.; Watanabe, M.; Takeharu, N.; Tarusawa, E.; Yagi, T.
10.1101/2023.04.14.536980 — neuroscience — Posted on 2023-04-15
2149 Light modulates task-dependent thalamo-cortical connectivity during an auditory attentional task
Paparella, I.; Campbell, I.; Sharifpour, R.; Beckers, E.; Berger, A.; Balda Aizpurua, J. F.; Koshmanova, E.; Mortazavi, N.; Talwar, P.; Degueldre, C.; Lamalle, L.; Sherif, S.; Phillips, C.; Maquet, P.; Vandewalle, G.
10.1101/2023.04.15.536992 — neuroscience — Posted on 2023-04-15
2151 Multiple behavioral mechanisms shape social behavioral development in a highly social cichlid fish
Harmon, I. P.; McCabe, E. A.; Graves, H. L.; Vergun, M. R.; Weinstein, J.; Boldt, C. M.; Lee, J.; Maurice, J. M.; Shah, M.; Solomon-Lane, T. K.
10.1101/2023.04.14.536957 — animal behavior and cognition — Posted on 2023-04-15
2152 Whole-brain deactivations precede uninduced mind-blanking reports
Boulakis, P. A.; Mortaheb, S.; Van Calster, L.; Majerus, S.; Demertzi, A.
10.1101/2023.04.14.536362 — neuroscience — Posted on 2023-04-15
2153 Nociception in chicken embryos, Part II: Embryonal development of electroencephalic neuronal activity in ovo as a prerequisite for nociception
Kollmansperger, S.; Anders, M.; Werner, J.; Saller, A. M.; Weiss, L.; Suess, S. C.; Reiser, J.; Schusser, B.; Baumgartner, C.; Schneider, G.; Fenzl, T.
10.1101/2023.04.14.536947 — neuroscience — Posted on 2023-04-15
2156 Upregulated GIRK2 counteracts ethanol-induced changes in excitability and respiration in human neurons
Prytkova, I. A.; Liu, Y.; Fernando, M. B.; Gameiro-Ros, I.; Popova, D.; Kamarajan, C.; Xuei, X.; Chorlian, D. B.; Edenberg, H. J.; Tischfield, J. A.; Porjesz, B.; Pang, Z. P.; Hart, R. P.; Goate, A. M.; Slesinger, P. A.
10.1101/2023.03.22.533236 — neuroscience — Posted on 2023-04-15
2157 Loss of Mitochondrial Enoyl CoA Reductase causes elevated ceramide levels and impairs iron metabolism
Dutta, D.; Kanca, O.; Byeon, S. K.; Marcogliese, P. C.; Zuo, Z.; Shridharan, R. V.; Park, J. H.; Undiagnosed Diseases Network, ; Lin, G.; Ge, M.; Heimer, G.; Kohler, J. N.; Wheeler, M. T.; Kaipparettu, B. A.; Pandey, A.; Bellen, H. J.
10.1101/2023.04.14.536458 — neuroscience — Posted on 2023-04-15
2160 Hypercholesterolemia aggravates in-stent restenosis in rabbits: a mitigating effect of stent surface modification with CD47-derived peptide
Fishbein, I.; Inamdar, V. V.; Alferiev, I. S.; Bratinov, G.; Zviman, M. M.; Yekhilevsky, A.; Nagaswami, C.; Gardiner, K. L.; Levy, R. J.; Stachelek, S. J.
10.1101/2023.02.27.530304 — bioengineering — Posted on 2023-04-15
2161 Biogeography and the evolution of acoustic communication in the polyploid North American gray treefrog complex
Booker, W. W.; Lemmon, E. M.; Lemmon, A. R.; Ptacek, M. B.; Hassinger, A. T.; Schul, J.; Gerhardt, H. C.
10.1101/2023.04.03.535469 — evolutionary biology — Posted on 2023-04-15
2166 Severe Central Nervous System Demyelination in Sanfilippo Disease
Taherzadeh, M.; Zhang, E.; Londono, I.; Song, S.-K.; Wang, S.; Cooper, J. D.; Kennedy, T. E.; Morales, C. R.; Chen, Z.; Lodygensky, G. A.; Pshezhetsky, A. V.
10.1101/2023.04.12.536631 — neuroscience — Posted on 2023-04-15
2169 Dynamic superresolution by Bayesian nonparametric image processing
Sgouralis, I.; Jalihal, A. P.; Xu, L. W. Q.; Walter, N. G.; Presse, S.
10.1101/2023.04.03.535459 — biophysics — Posted on 2023-04-15
2172 Spatial chromatin accessibility sequencing resolves high-order spatial interactions of epigenomic markers
Xie, Y.; Ruan, F.; Li, Y.; Luo, M.; Zhang, C.; Chen, Z.; Xie, Z.; Weng, Z.; Chen, W.; Chen, W.; Fang, Y.; Sun, Y.; Guo, M.; Wang, J.; Xu, S.; Wang, H.; Tang, C.
10.1101/2022.04.21.489011 — genomics — Posted on 2023-04-15
2176 The circulating phageome reflects bacterial infections
Haddock, N. L.; Barkal, L. J.; Ram-Mohan, N.; Kaber, G.; Chiu, C. Y.; Bhatt, A. S.; Yang, S.; Bollyky, P.
10.1101/2022.08.15.504009 — microbiology — Posted on 2023-04-15
2182 Genomic hallmarks and therapeutic implications of G0 cell cycle arrest in cancer
Wiecek, A. J.; Cutty, S. J.; Kornai, D.; Parreno-Centeno, M.; Gourmet, L. E.; Malagoli Tagliazucchi, G.; Jacobson, D. H.; Zhang, P.; Xiong, L.; Bond, G. L.; Barr, A. R.; Secrier, M.
10.1101/2021.11.12.468410 — cancer biology — Posted on 2023-04-15
2185 Benchmarking cassette-based deep mutagenesis by Golden Gate assembly
Daffern, N.; Baumer, Z. T.; Francino-Urdaniz, I. M.; Whitehead, T. A.
10.1101/2023.04.13.536781 — bioengineering — Posted on 2023-04-15
2187 Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin
Teixeira-Nunes, M.; Retailleau, P.; Raoux-Barbot, D.; Comisso, M.; Missinou, A. A.; Velours, C.; Plancqueel, S.; Ladant, D.; Mechold, U.; Renault, L.
10.1101/2023.01.13.523968 — biochemistry — Posted on 2023-04-15
2189 An improved genome assembly of the saguaro cactus (Carnegiea gigantea (Engelm.) Britton & Rose).
Copetti, D.; Burquez, A.; Shimizu, K. K.; Wing, R. A.; Sanderson, M. J.; Wojciechowski, M. F.
10.1101/2023.04.11.536419 — genomics — Posted on 2023-04-15
2197 Analysis of SARS-CoV-2 Recombinant Lineages XBC and XBC.1 in the Philippines and Evidence for Delta-Omicron Co-infection as a Potential Origin
Pangilinan, E. A. R.; Egana, J. M. C.; Mantaring, R. J. Q.; Telles, A. J. E.; Tablizo, F. A.; Lapid, C. M.; Yangzon, M. S. L.; Endozo, J. J. S.; Padilla, K. S. A. R.; Nipales, J. E.; Carandang, L. C. D. L.; Enriquez, Z. M. R.; Barot, T. A. U.; Manlimos, R. A.; Mangonon, K. N. P.; Plantig, M. E. L.; Araiza, S. M. M.; Llames, J.-H. S.; Punayan, K. P.; Serrano, R. P.; Drueco, A. M.; Lagnas, H. T.; Bistayan, P. A.; Aguilar, A. C.; Charisse Apo, J. G.; Austria, Y. V. D.; Bustamante, N. F. M.; Caelian, A. J. R.; Fernandez, R. E.; Galilea, X. A.; Gamboa, M. M.; Gervacio, C. J. A.; Mollejon, Z. V.; Pi
10.1101/2023.04.12.534029 — genetics — Posted on 2023-04-15
2198 Evolution of chemosensory tissues and cells across ecologically diverse Drosophilids
Bontonou, G.; Saint-Leandre, B.; Kafle, T.; Baticle, T.; Hassan, A.; Sanchez-Alcaniz, J. A.; Arguello, J. R.
10.1101/2023.04.14.536691 — evolutionary biology — Posted on 2023-04-15
2199 The 'Stem' and the 'Workers' of the mtDNA population of the cell. Evidence from mutational analysis.
Cote-L'Heureux, A.; Franco, M.; Maithania, Y. N. K.; Popadin, K.; Woods, D. C.; Tilly, J.; Khrapko, K.
10.1101/2023.04.14.536897 — genomics — Posted on 2023-04-15
2201 The Genetic Heterogeneity of Multimodal Human Brain Age
WEN, J.; Zhao, B.; Yang, Z.; Erus, G.; Skampardoni, I.; mamourian, e.; cui, y.; hwang, g.; bao, j.; boquet-pujadas, a.; zhou, z.; Veturi, Y.; Ritchie, M. D.; Thompson, P.; Shou, H.; Shen, L.; Toga, A. W.; davatzikos, c. O.
10.1101/2023.04.13.536818 — genetics — Posted on 2023-04-15
2206 Viral pIC-pocketing: RSV sequestration of eIF4F Initiation Complexes into bi-phasic biomolecular condensates
Jobe, F.; Kelly, J. T.; Simpson, J.; Wells, J.; Armstrong, S. D.; Spick, M.; Lacey, E.; Logan, L.; Geifman, N.; Hawes, P.; Bailey, D.
10.1101/2023.04.14.536931 — microbiology — Posted on 2023-04-15
2208 Spatial Multi-omics of Arterial Regions from Cardiac Allograft Vasculopathy Rejected Grafts
Nevarez-Mejia, J.; Pickering, H. C.; Sosa, R. A.; Fishbein, G. A.; Baldwin, W. M.; Fairchild, R. L.; Reed, E. F.
10.1101/2023.04.12.536667 — immunology — Posted on 2023-04-15
2209 A human in vitro neuronal model for studying homeostatic plasticity at the network level
Yuan, X.; Puvogel, S.; van Rhijn, J.-R.; Esteve-Codina, A.; Meijer, M.; Rouschop, S.; J.H. van Hugte, E.; Oudakker, A.; Schoenmaker, C.; Schubert, D.; Franke, B.; Nadif Kasri, N.
10.1101/2023.04.14.536851 — neuroscience — Posted on 2023-04-15
2211 Endocardial HDAC3 is required for myocardial trabeculation
Jang, J.; Bentsen, M.; Kim, Y. J.; Kim, E.; Garg, V.; Cai, C.-L.; Looso, M.; Li, D.
10.1101/2023.04.12.536668 — developmental biology — Posted on 2023-04-15
2212 Building functional circuits in multispecies brains.
Throesch, B.; Imtiaz, M. K.; Munoz-Castaneda, R.; Sakurai, M.; James, K. N.; Rodriguez, A.; Martin, G. S.; Lippi, G.; Kuprianov, S.; Wu, Z.; Osten, P.; Belmonte, J. C. I.; Wu, J.; Baldwin, K. K.
10.1101/2023.04.13.536815 — developmental biology — Posted on 2023-04-15
2213 Total Chemical Synthesis of Glycosylated TREM2 Ectodomain
Wijegunawardena, G.; Castillo, E.; Henrickson, B.; Davis, R.; Condello, C.; Wu, H.
10.1101/2023.04.14.536909 — biochemistry — Posted on 2023-04-14
2219 Engineering Nme2Cas9 Adenine Base Editors with Improved Activity and Targeting Scope
Bamidele, N.; Zhang, H.; Dong, X.; Gaston, N.; Cheng, H.; Kelly, K.; Watts, J. K.; Xie, J.; Gao, G.; Sontheimer, E. J.
10.1101/2023.04.14.536905 — molecular biology — Posted on 2023-04-14
2221 Gut microbiome-based prediction of autoimmune neuroinflammation
Steimle, A.; Neumann, M.; Grant, E.; Willieme, S.; De Sciscio, A.; Parrish, A.; Ollert, M.; Miyauchi, E.; Soga, T.; Fukuda, S.; Ohno, H.; Desai, M. S.
10.1101/2023.04.14.536901 — microbiology — Posted on 2023-04-14
2222 Targeting the catalytic activity of HDAC1 in T cells protects against experimental autoimmune encephalomyelitis
Zhu, C.; Stolz, V.; Simonovic, N.; Al-Rubaye, O.; Vcelkova, T.; Moos, V.; Hess, L.; Hagelkrueys, A.; Madern, M.; Reiter, W.; Meixner, A.; Bock, C.; Hartl, M.; Ellmeier, W.; Seiser, C.
10.1101/2023.04.14.536700 — immunology — Posted on 2023-04-14
2223 Paired yeast one-hybrid assays to detect DNA-binding cooperativity and antagonism across transcription factors
Berenson, A.; Lane, R.; Soto, L.; Patel, M.; Ciausu, C.; Chen, Y.; Shah, S.; Santoso, C.; Liu, X.; Spirohn, K.; Hao, T.; Hill, D. E.; Vidal, M.; Fuxman Bass, J. I.
10.1101/2023.04.14.536894 — systems biology — Posted on 2023-04-14
2226 In vivo structure probing of RNA in Archaea: Novel insights into the ribosome structure of Methanosarcina acetivorans
Williams, A. M.; Jolley, E.; Santiago-Martinez, M. G.; Chan, C. X.; Gutell, R.; Ferry, J. G.; Bevilacqua, P. C.
10.1101/2023.04.14.536875 — biochemistry — Posted on 2023-04-14
2229 Lepidoptera genomics based on 88 chromosomal reference sequences informs population genetic parameters for conservation
Bortoluzzi, C.; Wright, C. J.; Lee, S.; Cousins, T.; Genez, T. A. L.; Thybert, D.; Martin, F. J.; Haggerty, L.; The Darwin Tree of Life Project Consortium, ; Blaxter, M.; Durbin, R.
10.1101/2023.04.14.536868 — genomics — Posted on 2023-04-14
2230 Origin and early divergence of tandem duplicated sorbitol transporter genes in Rosaceae
Yang, F.; Luo, J.; Guo, W.; Zhang, Y.; Liu, Y.; Yu, Z.; Sun, Y.; Li, M.; Ma, F.; Zhao, T.
10.1101/2023.04.13.536778 — genomics — Posted on 2023-04-14
2231 Myosin inhibitor reverses hypertrophic cardiomyopathy in pediatric iPSC-cardiomyocytes to mirror variant correction
Kinnear, C.; Said, A.; Meng, G.; Zhao, Y.; Wang, E. Y.; Parmar, N.; Wei, W.; Billia, F.; Simmons, C. A.; Radisic, M.; Ellis, J.; Mital, S.
10.1101/2023.04.14.536782 — genetics — Posted on 2023-04-14
2232 Rapid bacteria-phage coevolution drives the emergence of multi-scale networks
Borin, J. M.; Lee, J. J.; Lucia-Sanz, A.; Gerbino, K. R.; Weitz, J. M.; Meyer, J. R.
10.1101/2023.04.13.536812 — evolutionary biology — Posted on 2023-04-14
2234 A maturation defective HIV-1 activates cGAS
Sumner, R. P.; Blest, H.; Lin, M.; Maluquer de Motes, C.; Towers, G. J.
10.1101/2023.04.14.536845 — microbiology — Posted on 2023-04-14
2236 Signal-amplification for cell-free biosensors, an analog-to-digital converter
Franco, R. A. L.; Brenner, G.; Zocca, V. F. B.; de Paiva, G. B.; Lima, R. N.; Rech, E. L.; Lins, M. R. d. C. R.; Pedrolli, D. B.
10.1101/2023.04.14.536885 — synthetic biology — Posted on 2023-04-14
2239 Osmolar modulation drives reversible cell cycle exit and human pluripotent cell differentiation via NF-κB and WNT signaling
Chui, J. S.-H.; Izuel-Idoype, T.; Qualizza, A.; Pires de Almeida, R.; van der Veer, B. K.; Vanmarcke, G.; Athanasouli, P.; Boon, R.; Vriens, J.; Koh, K. P.; van Grunsven, L. A.; Verfaillie, C.; Lluis, F.
10.1101/2023.04.14.536882 — developmental biology — Posted on 2023-04-14
2241 Impact of prenatal synthetic glucocorticoid exposure on the adolescent brain
Magalhes, R.; Goncalves, N.; Sousa, R.; Coelho, A.; Soares-Cunha, C.; Moreira, P.; Marques, P.; Tuulari, J. J.; Scheinin, N. M.; Karlsson, L.; Karlsson, H.; Sousa, N.; Rodrigues, A. J.
10.1101/2023.04.14.536872 — neuroscience — Posted on 2023-04-14
2247 Recursive self-embedded vocal motifs in wild orangutans
Lameira, A. R.; Hardus, M. E.; Ravignani, A.; Raimondi, T.; Gamba, M.
10.1101/2023.04.14.536836 — animal behavior and cognition — Posted on 2023-04-14
2250 Identification of multiple transcription factor genes potentially involved in the development of electrosensory versus mechanosensory lateral line organs
Minarik, M.; Modrell, M. S.; Gillis, J. A.; Campbell, A. S.; Fuller, I.; Lyne, R.; Micklem, G.; Gela, D.; Psenicka, M.; Baker, C. V. H.
10.1101/2023.04.14.536701 — developmental biology — Posted on 2023-04-14
2252 NEURAL BASIS OF SOUND-SYMBOLIC PSEUDOWORD-SHAPE CORRESPONDENCES
Barany, D. A.; Lacey, S.; Matthews, K. L.; Nygaard, L. C.; Sathian, K.
10.1101/2023.04.14.536865 — neuroscience — Posted on 2023-04-14
2253 Human visual cortex and deep convolutional neural network care deeply about object background
Loke, J.; Seijdel, N.; Snoek, L.; Sörensen, L. K. A.; van de Klundert, R.; van der Meer, M.; Quispel, E.; Cappaert, N.; Scholte, H. S.
10.1101/2023.04.14.536853 — neuroscience — Posted on 2023-04-14
2254 Reversal of cell, circuit and seizure phenotypes in a mouse model of DNM1 epileptic encephalopathy
Bonnycastle, K.; Dobson, K. L.; Blumrich, E.-M.; Gajbhiye, A.; Davenport, E. C.; Pronot, M.; Steinruecke, M.; Trost, M.; Gonzalez-Sulser, A.; Cousin, M. A.
10.1101/2023.04.14.536870 — neuroscience — Posted on 2023-04-14
2256 Ultraconformable cuff implants for long-term bidirectional interfacing of peripheral nerves at sub-nerve resolutions
Carnicer-Lombarte, A.; Boys, A.; Guemes, A.; Gurke, J.; Velasco-Bosom, S.; Hilton, S.; Barone, D. G.; Malliaras, G. G.
10.1101/2023.04.14.536862 — neuroscience — Posted on 2023-04-14
2258 Predicting hERG repolarization power at 37°C from recordings at room temperature
Ribeiro, B.; Alameh, M.; Montnach, J.; Ollivier, B.; Gibaud, S.; Feliciangeli, S.; Lesage, F.; Charpentier, F.; Loussouarn, G.; De Waard, M.; Baro, I.
10.1101/2023.04.13.536707 — physiology — Posted on 2023-04-14
2260 Circulating tumor extracellular vesicles to monitor metastatic prostate cancer genomics and transcriptomic evolution
Casanova-Salas, I.; Cordoba-Terreros, S.; Aguilar, D.; Agundez, L.; Brandariz, J.; Herranz, N.; Gonzalez, M.; Morales-Barrera, R.; Sierra, A.; Soriano-Navarro, M.; Cresta, P.; Simonetti, S.; Rodrigues, G.; Arce-Gallego, S.; Delgado, L.; Agusti, I.; Castellano-Sanz, E.; Mast, R.; de Albert, M.; Celma, A.; Santamaria, A.; Gonzalez, L.; Castro, N.; Suanes, M. d. M.; Hernandez-Losa, J.; Nonell, L.; Peinado, H.; Carles, J.; Mateo, J.
10.1101/2023.04.14.536404 — cancer biology — Posted on 2023-04-14
2261 In vivo CRISPR screen identifies KRAS-induced COX-2 as a driver of immune evasion and immunotherapy resistance in lung cancer
Boumelha, J.; de Castro, A.; Bah, N.; Cha, H.; de Carne Trecesson, S.; Rana, S.; Anastasiou, P.; Mugarza, E.; Moore, C.; Goldstone, R.; East, P.; Litchfield, K.; Lee, S.-H.; Molina-Arcas, M.; Downward, J.
10.1101/2023.04.13.536740 — cancer biology — Posted on 2023-04-14
2264 No general effects of advancing male age on ejaculates: a meta-analysis across the animal kingdom
Sanghvi, K.; Vega-Trejo, R.; Nakagawa, S.; Gascoigne, S. J. L.; Johnson, S.; Salguero-Gomez, R.; Pizzari, T.; Sepil, I.
10.1101/2023.04.14.536443 — evolutionary biology — Posted on 2023-04-14
2266 Determination of the factors responsible for host tropism of SARS-CoV-2-related bat coronaviruses
Fujita, S.; Kosugi, Y.; Kimura, I.; Tokunaga, K.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Ito, J.; Sato, K.
10.1101/2023.04.13.536832 — microbiology — Posted on 2023-04-14
2269 The Impact of Chronic Phthalate Exposure on Rodent Anxiety and Cognition
Yu, Z.; Iyer, L.; Swiercz, A. P.; Paronett, E.; Ramadan, M.; Marvar, P. J.; Posnack, N. G.
10.1101/2023.04.13.536567 — pharmacology and toxicology — Posted on 2023-04-14
2274 SEL1L-HRD1 ER-associated degradation is a new ataxia gene
Lin, L. L.; Torres, M.; Pederson, B.; Wang, H. H.; Wei, X.; Li, Z. J.; Liu, X.; Mao, H.; Hanzel, M.; Govek, E. E.; Lu, Y.; Wang, H.; Zhao, Z.; Hatten, M. E.; Sun, S. E.; Qi, L.
10.1101/2023.04.13.536796 — cell biology — Posted on 2023-04-14
2275 Do NSm virulence factors in the Bunyavirales order originate from Gn gene duplication?
Lefebvre, V.; Leon Foun Lin, R.; Cole, L.; Cosset, F.-L.; Fogeron, M.-L.; Bockmann, A.
10.1101/2023.04.13.536692 — bioinformatics — Posted on 2023-04-14
2276 Elevated temperature alters microbial communities, but not decomposition rates, during three years of in-situ peat decomposition
Roth, S. W.; Griffiths, N. A.; Kolka, R. K.; Oleheiser, K. C.; Carrell, A. A.; Klingeman, D. M.; Seibert, A.; Chanton, J.; Hanson, P. J.; Schadt, C. W.
10.1101/2023.04.13.536719 — ecology — Posted on 2023-04-14
2279 Mechanisms of carbon dioxide detection in the earthworm Dendrobaena veneta.
Smith, E. J.; Ryan, J. L.; Lopresti, S. A.; Haghnazari, D. B.; Anderson, K. A.; Lipson, S. J.; Johnson, E. C.; Silver, W. L.; Saunders, C. J.
10.1101/2023.04.12.536649 — physiology — Posted on 2023-04-14
2280 A CRISPR-drug perturbational map for identifying new compounds to combine with commonly used chemotherapeutics.
Lee, H.-M.; Wright, W. C.; Pan, M.; Low, J.; Currier, D.; Fang, J.; Singh, S.; Nance, S.; Delahunty, I.; Kim, Y.; Chapple, R. H.; Zhang, Y.; Liu, X.; Steele, J. A.; Qi, J.; Pruett-Miller, S. M.; Easton, J.; Chen, T.; Yang, J.; Durbin, A. D.; Geeleher, P.
10.1101/2023.04.12.536612 — cancer biology — Posted on 2023-04-14
2284 A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats
de Jong, T. V.; Pan, Y.; Rastas, P.; Munro, D.; Tutaj, M.; Akil, H.; Benner, C.; Chitre, A. S.; Chow, W.; Colonna, V.; Dalgard, C. L.; Demos, W. M.; Doris, P. A.; Garrison, E.; Geurts, A.; Gunturkun, H. M.; Guryev, V.; Hourlier, T.; Howe, K.; Huang, J.; Kalbfleisch, T.; Kim, P.; Li, L.; Mahaffey, S.; Martin, F. J.; Mohammadi, P.; Ozel, A. B.; Polesskaya, O.; Pravenec, M.; Prins, P.; Sebat, J.; Smith, J. R.; Solberg Woods, L. C.; Tabakoff, B.; Tracey, A.; Uliano-Silva, M.; Villani, F.; Wang, H.; Sharp, B. M.; Telese, F.; Jiang, Z.; Saba, L.; Wang, X.; Murphy, T. D.; Palmer, A. A.; Kwitek, A. E.
10.1101/2023.04.13.536694 — genomics — Posted on 2023-04-14
2288 Wide scope analysis of bioactive lipids, including steroids, bile acids, and polyunsaturated fatty acid metabolites, in human plasma by LC/MS/MS
Nakatani, K.; Izumi, Y.; Umakoshi, H.; Yokomoto-Umakoshi, M.; Nakaji, T.; Kaneko, H.; Nakao, H.; Ogawa, Y.; Ikeda, K.; Bamba, T.
10.1101/2023.04.13.536679 — systems biology — Posted on 2023-04-14
2290 Spatial autocorrelation dimension as a potential determinant for the temporal persistence of human atrial and ventricular fibrillation.
Dharmaprani, D.; Jenkins, E. V.; Tiver, K.; Quah, J. X.; Mitchell, L.; Tung, M.; Ahmad, W.; Stoyanov, N.; Aguilar, M.; Nash, M. P.; Clayton, R. H.; Nattel, S.; Ganesan, A. N.
10.1101/2023.04.12.536515 — physiology — Posted on 2023-04-14
2291 Biomaterial based implants caused remote liver fatty deposition through activated blood-derived Kupffer cells
Peng, Z.; Xie, C.; Jin, S.; Hu, J.; Yao, X.; Ye, J.; Zhang, X.; Lim, J. X.; Wu, B.; Wu, H.; Liang, R.; Wen, Y.; Huang, J.; Zou, X.; Hongwei, O.
10.1101/2023.04.12.536663 — pharmacology and toxicology — Posted on 2023-04-14
2292 Combinatorial genetic strategy accelerates the discovery of cancer genotype-phenotype associations
Li, S.; Wong, A.; Sun, H.; Bhatia, V.; Javier, G.; Jana, S.; Mongomery, R. B.; Wright, J. L.; Lam, H.-M.; Hsieh, A. C.; Faltas, B. M.; Haffner, M. C.; Lee, J. K.
10.1101/2023.04.12.536652 — cancer biology — Posted on 2023-04-14
2293 Surface-guided computing to analyze subcellular morphology and membrane-associated signals in 3D
Zhou, F. Y.; Weems, A.; Gihana, G. M.; Chen, B.; Chang, B.-J.; Driscoll, M.; Danuser, G.
10.1101/2023.04.12.536640 — bioinformatics — Posted on 2023-04-14
2294 Identification of Mirror Repeats in Viral Genomes using FPCB Analysis
Yadav, P.; Kumari, J.; Yadav, P.; Yadav, R.; Yadav, S.; Sharma, D.; Singh, A.; Sehrawat, B.; Yadav, M.; Yadav, S.
10.1101/2023.04.13.536685 — bioinformatics — Posted on 2023-04-14
2297 Generalized mutualisms promote range expansion in both plant and ant partners
Nathan, P.; Guenard, B.; Economo, E. P.; Simonsen, A.; Frederickson, M.
10.1101/2023.04.12.536632 — ecology — Posted on 2023-04-14
2301 Characterizing the monomer-dimer equilibrium of UbcH8/Ube2L6: A combined SAXS and NMR study
Kahraman, K.; Robson, S. A.; Gocenler, O.; Tozkoparan, C. D.; Klein, J. M.; Yenici, C. M.; Haas, A. L.; Ziarek, J. J.; Dag, C.
10.1101/2023.04.13.536743 — biochemistry — Posted on 2023-04-14
2302 CRISPR/Cas9-based repeat depletion for the high-throughput genotyping of complex plant genomes
Rossato, M.; Marcolungo, L.; De Antoni, L.; Lopatriello, G.; Bellucci, E.; Cortinovis, G.; Frascarelli, G.; Nanni, L.; Bitocchi, E.; Di Vittori, V.; Vincenzi, L.; Lucchini, F.; Bett, K.; Ramsay, L.; Konkin, D. J.; Delledonne, M.; Papa, R.
10.1101/2022.11.22.517518 — genomics — Posted on 2023-04-14
2303 Understanding inter-individual social networks in mixed-species bird flocks
Bharadwaj, A.; Thapa, A.; Bhat, A.; Biswakarma, A.; Tamang, B.; Munda, B.; Biswakarma, B.; Pradhan, D. K.; Tamang, D.; Pradhan, K.; K Rai, M.; Chamling Rai, P.; Rai, R.; Rai, S.; Srinivasan, U.
10.1101/2023.04.13.536662 — ecology — Posted on 2023-04-14
2305 The ASC inflammasome adapter controls the severity of inflammation-related AA amyloidosis
Losa, M.; Emmenegger, M.; De Rossi, P.; Schuerch, P. M.; Serdiuk, T.; Pengo, N.; Capron, D.; Bieli, D.; Rupp, N. J.; Carta, M. C.; Frontzek, K. J.; Lysenko, V.; Reimann, R.; Lakkaraju, A. K.; Nuvolone, M.; Westermark, G. T.; Nilsson, K. P.; Polymenidou, M.; Theocharides, A. P.; Hornemann, S.; Picotti, P.; Aguzzi, A.
10.1101/2021.05.01.442282 — molecular biology — Posted on 2023-04-14
2306 SARS-CoV-2 NSP5 Antagonizes MHC II Expression by Subverting Histone Deacetylase 2
Taefehshokr, N.; Lac, A.; Vrieze, A. M.; Dickson, B. H.; Guo, P. N.; Jung, C.; Blythe, E. N.; Fink, C.; Dikeakos, J. D.; Dekaban, G. A.; Heit, B.
10.1101/2023.02.10.528032 — immunology — Posted on 2023-04-14
2307 NAD+ metabolism is a key modulator of bacterial respiratory epithelial infections
Klabunde, B.; Wesener, A.; Bertrams, W.; Beinborn, I.; Paczia, N.; Surmann, K.; Blankenburg, S.; Wilhelm, J.; Serrania, J.; Knoops, K.; Elsayed, E. M.; Laakmann, K.; Jung, A. L.; Kirschbaum, A.; Abu Mraheil, M.; Becker, A.; Volker, U.; Vollmeister, E.; Benedikter, B. J.; Schmeck, B.
10.1101/2023.04.13.536709 — immunology — Posted on 2023-04-14
2309 Recent O-antigen diversification masks highly pathogenic STEC O104:H4
Lang, C.; Fruth, A.; Campell, I. W.; Jenkins, C.; Smith, P.; Strockbine, N.; Weill, F.-X.; Nübel, U.; Grad, Y. H.; Waldor, M. K.; Flieger, A.
10.1101/2022.09.15.508078 — microbiology — Posted on 2023-04-14
2311 Competence for transcellular infection in the root cortex involves a post-replicative, cell-cycle exit decision in Medicago truncatula
Batzenschlager, M.; Lace, B.; Zhang, N.; Su, C.; Egli, S.; Krohn, P.; Salfeld, J.; Ditengou, F. A.; Laux, T.; Ott, T.
10.1101/2023.03.28.534635 — plant biology — Posted on 2023-04-14
2312 Dynamic molecular mechanism of the nuclear pore complex permeability barrier
Kozai, T.; Fernandez-Martinez, J.; van Eeuwen, T.; Gallardo, P.; Kapinos, L. E.; Mazur, A.; Zhang, W.; Tempkin, J.; Panatala, R.; Delgado-Izquierdo, M.; Raveh, B.; Sali, A.; Chait, B. T.; Veenhoff, L. M.; Rout, M. P.; Lim, R. Y. H.
10.1101/2023.03.31.535055 — biophysics — Posted on 2023-04-14
2314 Optimal HLA imputation of admixed population with dimension reduction
Douillard, V.; dos Santos Brito Silva, N.; Bourguiba-Hachemi, S.; Naslavsky, M. S.; Scliar, M. O.; Duarte, Y. A. O.; Zatz, M.; Passos-Bueno, M. R.; Limou, S.; Gourraud, P.-A.; Launay, E.; Castelli, E. C.; SNP-HLA Reference Consortium (SHLARC), ; Vince, N.
10.1101/2023.04.12.536582 — genomics — Posted on 2023-04-14
2316 FBXL4 deficiency promotes mitophagy by elevating NIX.
Elcocks, H.; Brazel, A. J.; McCarron, K. R.; Kaulich, M.; Husnjak, K.; Mortiboys, H. J.; Clague, M. J.; Urbe, S.
10.1101/2022.10.11.511735 — cell biology — Posted on 2023-04-14
2317 Strain-dependent induction of primary bile acid 7-dehydroxylation by cholic acid
Vico Oton, E.; Volet, C.; Jacquemin, N. L. M.; Dong, Y.; Hapfelmeier, S.; Meibom, K. L.; Bernier-Latmani, R.
10.1101/2022.02.15.480494 — microbiology — Posted on 2023-04-14
2320 An unsupervised learning approach uncovers divergent mesenchymal-like gene expression programs across human neuroblastoma tumors, preclinical models, and chemotherapy-exposed tumors.
Chapple, R. H.; Liu, X.; Natarajan, S.; Alexander, M. I. M.; Kim, Y.; Patel, A.; LaFlamme, C.; Pan, M.; Wright, W. C.; Lee, H.-M.; Zhang, Y.; Lu, M.; Koo, S. C.; Long, C.; Harper, J.; Savage, C.; Johnson, M. D.; Confer, T.; Akers, W. J.; Dyer, M. A.; Sheppard, H.; Geeleher, P.
10.1101/2023.04.13.536639 — cancer biology — Posted on 2023-04-14
2323 A novel high-throughput assay identifies small molecules with activity against persister cells
Petersen, M. E.; Hansen, L. K.; Kelley, N. M.; Wood, T. K.; Pedersen Jorgensen, N.; Ostergaard, L. J.; Meyer, R. L.
10.1101/2023.04.13.536681 — microbiology — Posted on 2023-04-14
2325 Genetic and karyotype divergence between parents affect clonality and sterility in hybrids
Marta, A.; Tichopad, T.; Bartos, O.; Klima, J.; shah, M.; Bohlen, V. S.; Bohlen, J.; Halacka, K.; Choleva, L.; Stöck, M.; Dedukh, D.; Janko, K.
10.1101/2023.04.11.536494 — evolutionary biology — Posted on 2023-04-14
2326 Compilation of all known protein changes in the human Alzheimer's disease brain
Askenazi, M.; Kavanagh, T.; Pires, G.; Ueberheide, B.; Wisniewski, T.; Drummond, E.
10.1101/2023.04.13.536828 — neuroscience — Posted on 2023-04-14
2327 TDP 2 modulates the expression of estrogen-responsive oncogenes
Manguso, N.; Kim, M.; Joshi, N.; Al Mahmud, R.; Cortes-Ledesma, F.; Cui, X.; Yamada, S.; Ito, J.; Takeda, S.; Giuliano, A. E.; You, S.; Tanaka, H.
10.1101/2022.06.01.494417 — molecular biology — Posted on 2023-04-14
2334 Jaccard dissimilarity in stochastic community models based on the species-independence assumption
Iritani, R.; Ontiveros, V. L. J.; Alonso, D.; Capitan, J. A.; Godsoe, W.; Tatsumi, S.
10.1101/2022.12.13.520233 — ecology — Posted on 2023-04-14
2338 The super-enhancer landscape reflects molecular subgroups of adrenocortical carcinoma
Gunz, S.; Kerdivel, G.; Meirer, J.; Shapiro, I.; Regazzon, B.; Amrouche, F.; Calmejane, M.-A.; Hamroune, J.; Sigala, S.; Berruti, A.; Bertherat, J.; Assie, G.; Hantel, C.; Boeva, V.
10.1101/2023.04.05.535576 — cancer biology — Posted on 2023-04-14
2340 Reinstating targeted protein degradation with DCAF1 PROTACs in CRBN PROTAC resistant settings
Schroeder, M.; Renatus, M.; Liang, X.; Meili, F.; Ferrand, S.; Gauter, F.; Li, X.; Sigoillot, F.; Gleim, S.; Stachyra, M.-T.; Thomas, J.; Schirle, M.; Zoller, T.; Begue, D.; Lefeuvre, P.; Chung, B.; Ma, R.; Carbonneau, S.; Pinch, B.; Schmiedeberg, N.; Imbach, P.; Hofmann, A.; Rey, R.; Gorses, D.; Calkins, K.; Bauer-Probst, B.; Maschlej, M.; Niederst, M.; Maher, R.; Henault, M.; Alford, J.; Ahrne, E.; Hollingworth, G.; Thomae, N. H.; Vulpetti, A.; Radimerski, T.; Holzer, P.; Thoma, C. R.
10.1101/2023.04.09.536153 — biochemistry — Posted on 2023-04-14
2343 A spatial map of hepatic mitochondria uncovers functional heterogeneity shaped by nutrient-sensing signaling
Kang, S. W. S.; Cunningham, R. P.; Miller, C. B.; Cultraro, C. M.; Hernandez, J.; Jenkins, L. M.; Lobanov, A.; Cam, M.; Porat-Shliom, N.
10.1101/2023.04.13.536717 — cell biology — Posted on 2023-04-13
2344 Amoeboid cells undergo durotaxis with soft end polarized NMIIA
Yi, X.; Chen, P.; Kang, C.; Li, D.; Yang, Y.; Cai, H.; Li, B.; Wu, C.
10.1101/2023.04.13.536664 — cell biology — Posted on 2023-04-13
2349 Characterizing the monomer-dimer equilibrium of UbcH8/Ube2L6: A combined SAXS and NMR study
Kahraman, K.; Robson, S. A.; Gocenler, O.; Tozkoparan, C. D.; Klein, J. M.; Yenici, C. M.; Haas, A. L.; Ziarek, J. J.; Dag, C.
10.1101/2023.04.13.536743 — biochemistry — Posted on 2023-04-13
2350 Optimization of Cas12a for multiplexed genome-scale transcriptional activation
Griffith, A. L.; Zheng, F.; McGee, A. V.; Miller, N.; Szegletes, Z. M.; Reint, G.; Gademann, F.; Nwolah, I.; Hegde, M.; Liu, Y. V.; Goodale, A.; Doench, J. G.
10.1101/2023.04.13.536783 — genomics — Posted on 2023-04-13
2351 Redefining rock doves, Columba livia, using historical whole genome sequences
Hernandez Alonso, G.; Ramos-Magridal, J.; Pacheco, G.; van Grouw, H.; Cavill, E. L.; Ciucani, M. M.; Sinding, M.-H. S.; Gopalakrishnan, S.; Gilbert, M. T. P.
10.1101/2023.04.12.536150 — evolutionary biology — Posted on 2023-04-13
2352 Disturbance increases functional diversity but decreases phylogenetic diversity of an arboreal tropical ant community
Hoenle, P. O.; Plowman, N.; Matos-Maravi, P.; de Bello, F.; Bishop, T. R.; Libra, M.; Idigel, C.; Rimandai, M.; Klimes, P.
10.1101/2023.04.13.536723 — ecology — Posted on 2023-04-13
2354 Benchmarking cassette-based deep mutagenesis by Golden Gate assembly
Whitehead, T. A.; Daffern, N.; Baumer, Z. T.; Francino-Urdaniz, I. M.
10.1101/2023.04.13.536781 — bioengineering — Posted on 2023-04-13
2355 Genome editing in the mouse brain with minimally immunogenic Cas9 RNPs
Stahl, E. C.; Sabo, J. K.; Kang, M. H.; Allen, R.; Applegate, E.; Kim, S. E.; Kwon, M.; Seth, A.; Lemus, N.; Salinas-Rios, V.; Soczek, K.; Trinidad, M.; Vo, L. T.; Jeans, C.; Wozniak, A.; Morris, T.; Kimberlin, A.; Foti, T.; Savage, D. F.; Doudna, J. A.
10.1101/2023.04.13.536294 — bioengineering — Posted on 2023-04-13
2356 Base Editor Scanning Reveals Activating Mutations of DNMT3A
Garcia, E. M.; Lue, N. Z.; Liang, J. K.; Lieberman, W. K.; Hwang, D. D.; Woods, J.; Liau, B.
10.1101/2023.04.12.536656 — biochemistry — Posted on 2023-04-13
2357 Selenium reduction of ubiquinone via SQOR suppresses ferroptosis
Lee, N.; Park, S. J.; Lange, M.; Tseyang, T.; Doshi, M. B.; Kim, T.; Song, Y.; Kim, D.; Greer, P. L.; Olzmann, J. A.; Spinelli, J.; Kim, D.
10.1101/2023.04.13.535674 — biochemistry — Posted on 2023-04-13
2363 Transcriptomic profiling of nuclei from PFA-fixed and FFPE brain tissues
Guo, Y.; Ma, J.; Dang, K.; Li, Z.; Ge, Q.; Huang, Y.; Wang, G.-Z.; Zhao, X.
10.1101/2023.04.13.536693 — molecular biology — Posted on 2023-04-13
2365 Volatile profiling distinguishes Streptococcus pyogenes from other respiratory streptococcal species
Berna, A. Z.; Merriman, J. A.; Mellet, L.; Parchment, D. K.; Caparon, M. G.; Odom John, A.
10.1101/2023.04.13.536753 — microbiology — Posted on 2023-04-13
2367 Dual functioning by the PhoR sensor is a key determinant to Mycobacterium tuberculosis virulence
Singh, P. R.; Goar, H.; Paul, P.; Mehta, K.; Bamniya, B.; Anil Kumar, V.; Bansal, R.; Khan, H.; Karthikeyan, S.; SARKAR, D.
10.1101/2023.04.13.536687 — microbiology — Posted on 2023-04-13
2370 More than just an Eagle Killer: The freshwater cyanobacterium Aetokthonos hydrillicola produces highly toxic dolastatin derivatives
Schwark, M.; Martinez Yerena, J. A.; Roehrborn, K.; Hrouzek, P.; Divoka, P.; Stenclova, L.; Delawska, K.; Enke, H.; Vorreiter, C.; Wiley, F.; Sippl, W.; Sobotka, R.; Saha, S.; Wilde, S. B.; Mares, J.; Niedermeyer, T. H. J.
10.1101/2023.04.12.536103 — microbiology — Posted on 2023-04-13
2371 A cell-free strategy for profiling intracellular antibiotic sensitivity and resistance
Chengan, K.; Hind, C.; Nagappa, L.; Wand, M. E.; Hanson, T.; Escolano, R. M.; Tsaousis, A.; Bengoechea, J. A.; Sutton, J. M.; Smales, C. M.; Moore, S. J.
10.1101/2023.04.13.536698 — microbiology — Posted on 2023-04-13
2373 Design of a stem cell-based therapy for ependymal repair in hydrocephalus associated with germinal matrix hemorrhages
Rodriguez-Perez, L. M.; Ojeda-Perez, B.; Garcia-Bonilla, M.; Lopez-de-San-Sebastian, J.; Gonzalez-Garcia, M.; Fernandez-Munoz, B.; Sanchez-Pernaute, R.; Garcia-Martin, M. L.; Dominguez-Pino, D.; Cardenas-Garcia, C.; Jimenez-Lara, A. J.; Paez-Gonzalez, P.
10.1101/2023.04.13.536749 — neuroscience — Posted on 2023-04-13
2376 Interspecies blastocyst complementation generates functional rat cell-derived forebrain tissues in mice
Huang, J.; He, B.; Yang, X.; Long, X.; Wei, Y.; Gao, Y.; Fang, Y.; Ying, W.; Wang, Z.; Li, C.; Zhou, Y.; Li, S.; Shi, L.; Guo, F.; Zhou, H.; Yang, H.; Wu, J.
10.1101/2023.04.13.536774 — developmental biology — Posted on 2023-04-13
2377 The influence of environment geometry on subiculum boundary vector cells in adulthood and early development
Muessig, L.; Ribeiro Rodrigues, F.; Bjerknes, T.; Towse, B.; Barry, C.; Burgess, N.; Moser, E. I.; Moser, M.-B.; Cacucci, F.; Wills, T. J.
10.1101/2023.04.13.536690 — neuroscience — Posted on 2023-04-13
2378 Impact of inflammatory preconditioning on murine microglial proteome response induced by focal ischemic brain injury
Helbing, D. L.; Haas, F.; Cirri, E.; Rahnis, N.; Dau, T. T. D.; Sacramento, E. K.; Oraha, N.; Boehm, L.; Morrison, H.; Bauer, R.
10.1101/2023.04.13.536755 — neuroscience — Posted on 2023-04-13
2379 Regulation of the circadian clock in C. elegans by clock gene homologs kin-20 and lin-42
Lamberti, M. L.; Spangler, R. K.; Cerdeira, V.; Ares, M.; Rivollet, L.; Ashley, G. E.; Coronado, A. R.; Tripathi, S.; Spiousas, I.; Ward, J. D.; Partch, C. L.; Benard, C. Y.; Goya, M. E.; Golombek, D. A.
10.1101/2023.04.13.536481 — neuroscience — Posted on 2023-04-13
2380 GluK2 is a target for gene therapy in drug-resistant Temporal Lobe Epilepsy
Boileau, C.; Deforges, S.; Peret, A.; Scavarda, D.; Bartholomei, F.; Giles, A.; Partouche, N.; Gautron, J.; Viotti, J.; Janowitz, H.; Penchet, G.; Marchal, C.; Lagarde, S.; Trebuchon, A.; Villeneuve, N.; Rumi, J.; Marissal, T.; Khazipov, R.; Khalilov, I.; Martineau, F.; Marechal, M.; Lepine, A.; Milh, M.; Figarella-Branger, D.; Dougy, E.; Tong, S.; Appay, R.; Baudouin, S.; Mercer, A.; Smith, J. B.; Danos, O.; Porter, R.; Mulle, C.; Crepel, V.
10.1101/2023.04.13.536748 — neuroscience — Posted on 2023-04-13
2383 Global neuronal activity drives cerebrospinal fluid motion mediated by brain blood volume changes in humans
Zimmermann, J.; Boudriot, C.; Eipert, C.; Hoffmann, G.; Nuttall, R.; Schneider, S.; Schmitzer, L.; Kufer, J.; Kaczmarz, S.; Hedderich, D.; Ranft, A.; Golkowski, D.; Priller, J.; Zimmer, C.; Ilg, R.; Schneider, G.; Preibisch, C.; Sorg, C.; Zott, B.
10.1101/2023.04.13.536674 — neuroscience — Posted on 2023-04-13
2385 SARS-CoV-2 selectively induces the expression of unproductive splicing isoforms of interferon, class I MHC and splicing machinery genes
Lüscher Dias, T.; Mamede Costa Andrade da Conceicao, I.; Toledo, N. E.; Queiroz, L. R.; de Castro, I. M. S.; Polidoro, R. B.; Del-Bem, L.-E.; Nakaya, H.; Franco, G. R.
10.1101/2023.04.12.536671 — bioinformatics — Posted on 2023-04-13
2388 Cell specificity of adeno-associated virus (AAV) serotypes in human cortical organoids
Stanton, M. M.; Hariani, H. N.; Sorokin, J.; Taylor, P. M.; Modan, S.; Rash, B. G.; Rao, S. B.; Enriquez, L.; Quang, D.; Hsu, P.-K.; Paek, J.; Owango, D.; Castrillo, C.; Nicola, J.; Ramkumar, P.; Lash, A.; Flanzer, D.; Shah, K.; Kato, S.; Skibinski, G.
10.1101/2023.04.13.536491 — neuroscience — Posted on 2023-04-13
2389 Sex-specific developmental changes in spinal cord pain pathways following neonatal inflammation
Hedley, K. E.; Cuskelly, A.; Quinn, R. K.; Callister, R. J.; Hodgson, D. M.; Tadros, M. A.
10.1101/2023.04.12.536647 — neuroscience — Posted on 2023-04-13
2390 Validation of Tau Antibodies for Use in Western Blotting and Immunohistochemistry
Ellis, M. J.; Lekka, C.; Tulmin, H.; O'Brien, D. P.; Dhayal, S.; Zeissler, M.-L.; Knudsen, J. G.; Kessler, B. M.; Morgan, N. G.; Todd, J. A.; Richardson, S. J.; Stefana, I. M.
10.1101/2023.04.13.536711 — neuroscience — Posted on 2023-04-13
2391 Parallel shifts in flight-height associated with altitude across incipient Heliconius species
Rivas-Sanchez, D. F.; Gantiva-Q, C. H.; Pardo-Diaz, C.; Salazar, C.; Montgomery, S. H.; Merrill, R. M.
10.1101/2023.04.12.536626 — evolutionary biology — Posted on 2023-04-13
2394 SARS-CoV-2 spike antigen-specific B cell and antibody responses in pre-vaccination period COVID-19 convalescent males and females with or without post-covid condition
Limoges, M.-A.; Quenum, A. J. I.; Chowdhury, M. M. H.; Rexhepi, F.; Namvarpour, M.; Akbari, S. A.; Rioux-Perreault, C.; Nandi, M.; Lucier, J.-F.; Lemaire-Paquette, S.; Premkumar, L.; Durocher, Y.; Cantin, A.; Levesque, S.; Menendez, A.; Dionne, I. J.; Ilangumaran, S.; Allard-Chamard, H.; Piche, A.; Ramanathan, S.
10.1101/2023.04.13.535896 — immunology — Posted on 2023-04-13
2396 Suppressed vascular Rho-kinase activation is a protective cardiovascular mechanism in obese female mice
Barbosa, G. S.; Costa, R. M.; Awata, W. M.; Singh, S.; Alves, J. V.; Bruder-Nascimento, A.; Correa, C. R.; Bruder-Nascimento, T.
10.1101/2023.04.12.536489 — physiology — Posted on 2023-04-13
2399 An Exploratory Multi-Session Study of Learning High-Dimensional Body-Machine Interfacing for Assistive Robot Control
Lee, J. M.; Gebrekristos, T.; De Santis, D.; Javaremi, M. N.; Gopinath, D.; Parikh, B.; Mussa-Ivaldi, F. A.; Argall, B. D.
10.1101/2023.04.12.536624 — bioengineering — Posted on 2023-04-13
2402 Proteasome gene expression is controlled by the coordinated functions of multiple transcription factors
Gilda, J. E.; Nahar, A.; Kasiviswanathan, D.; Tropp, N.; Gilinski, T.; Lahav, T.; Mandel-Gutfreund, Y.; Park, S.; Cohen, S.
10.1101/2023.04.12.536627 — cell biology — Posted on 2023-04-13
2403 Inhibition of Type I PRMTs Reforms Muscle Stem Cell Identity Enhancing their Therapeutic Capacity
Dominici, C.; Villarreal, O. D.; Dort, J.; Heckel, E.; Wang, Y. C.; Ragoussis, I.; Joyal, J.-S.; Dumont, N.; Richard, S.
10.1101/2023.01.03.522550 — molecular biology — Posted on 2023-04-13
2406 Unlocking the potential of miR-19b in the regulation of temozolomide response in glioblastoma patients via targeting PPP2R5E, a subunit of the protein phosphatase 2A complex
Kashani, E.; Hlavackova, K.; Haemmig, S.; Sadowski, M. C.; Phour, J.; Baumgartner, U.; Mueller-Wirth, N.; Trefny, C.; Sharf Den Abu Fakher, B.; Nydegger, C.; Maragkou, T.; Schucht, P.; Perren, A.; Zinn, P.; Luedi, M.; Marti, T. M.; Krebs, P.; Vassella, E.
10.1101/2023.01.16.524069 — cancer biology — Posted on 2023-04-13
2407 Unzipped assemblies of polyploid root-knot nematode genomes reveal new kinds of unilateral composite telomeric repeats
Zotta Mota, A. P.; Koutsovoulos, G. D.; Perfus-Barbeoch, L.; Despot-Slade, E.; Labadie, K.; Aury, J.-M.; Robbe-Sermesant, K.; Bailly-Bechet, M.; Belser, C.; Pere, A.; Rancurel, C.; Kozlowski, D. K.; Hassanaly-Goulamhoussen, R.; Da Rocha, M.; Noel, B.; Mestrovic-Radan, N.; Wincker, P.; Danchin, E. G.
10.1101/2023.03.29.534350 — genomics — Posted on 2023-04-13
2408 Selection on many loci drove the origin and spread of a key innovation
Stankowski, S.; Zagrodzka, Z. B.; Garlovsky, M. D.; Pal, A.; Shipilina, D.; Garcia Castillo, D. F.; Le Moan, A.; Leder, E.; Reeve, J.; Johannesson, K.; Westram, A.; Butlin, R. K.
10.1101/2023.02.13.528213 — evolutionary biology — Posted on 2023-04-13
2410 Ontogeny of superorganisms:Social control of queen specialization in ants
Majidifar, V.; Psalti, M. N.; Coulm, M.; Fetzer, E.; Teggers, E.-M.; Rotering, F.; Gruenewald, J.; Mannella, L.; Reuter, M.; Unte, D.; Libbrecht, R.
10.1101/2022.03.08.483434 — evolutionary biology — Posted on 2023-04-13
2411 TAR Syndrome-associated Rbm8a deficiency causes hematopoietic defects and attenuates Wnt/PCP signaling
Kocere, A.; Chiavacci, E.; Mendez-Acevedo, K. M.; Soneson, C.; Hiltabidle, M. S.; MacGowan, J. S.; Panakova, D.; Williams, M. L. K.; Robinson, M. D.; Mosimann, C.; Burger, A.
10.1101/2023.04.12.536513 — developmental biology — Posted on 2023-04-13
2412 Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT
Al Khatib, I.; Deng, J.; Lei, Y.; Torres-Odio, S.; Rojas, G. R.; Newman, L. E.; Chung, B. K.; Symes, S. A.; Zhang, H.; Huang, S.-y. N.; Pommier, Y.; Khan, A.; Shadel, G. S.; West, P.; Gibson, W.; Shutt, T.
10.1101/2022.03.08.483326 — cell biology — Posted on 2023-04-13
2413 Landscape drives zoonotic malaria prevalence in non-human primates
Johnson, E.; Sunil Kumar Sharma, R.; Ruiz Cuenca, P.; Byrne, I.; Salgado-Lynn, M.; Suraya Shahar, Z.; Col Lin, L.; Zulkifli, N.; Dilaila Mohd Saidi, N.; Drakeley, C.; Matthiopoulos, J.; Nelli, L.; Fornace, K.
10.1101/2022.06.17.496284 — ecology — Posted on 2023-04-13
2414 A descending inhibitory mechanism of nociception mediated by an evolutionarily conserved neuropeptide system in Drosophila
Oikawa, I.; Kondo, S.; Hashimoto, K.; Yoshida, A.; Hamajima, M.; Tanimoto, H.; Furukubo-Tokunaga, K.; Honjo, K.
10.1101/2022.03.08.483420 — neuroscience — Posted on 2023-04-13
2416 Modelling human KCNT1-epilepsy in Drosophila: a seizure phenotype and drug responses
Hussain, R.; Lim, C. X.; Shaukat, Z.; Islam, A.; Caseley, E.; Lippiat, J. D.; Rychkov, G.; Ricos, M. G.; Dibbens, L. M.
10.1101/2023.04.11.536495 — neuroscience — Posted on 2023-04-13
2417 Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions
Tai, Y.-H.; Engels, D.; Locatelli, G.; Emmanouilidis, I.; Fecher, C.; Theodorou, D.; Mueller, S. A.; Licht-Mayer, S.; Kreutzfeldt, M.; Wagner, I.; Prudente de Mello, N.; Gkotzamani, S.-N.; Trovo, L.; Kendirli, A.; Aljovic, A.; Breckwoldt, M. O.; Naumann, R.; Bareyre, F. M.; Perocchi, F.; Mahad, D.; Merkler, D.; Lichtenthaler, S. F.; Kerschensteiner, M.; Misgeld, T.
10.1101/2023.04.03.535354 — neuroscience — Posted on 2023-04-13
2418 Cryo-EM structures of tau filaments from SH-SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration
Tarutani, A.; Lövestam, S.; Zhang, X.; Kotecha, A.; Robinson, A. C.; Mann, D. M. A.; Saito, Y.; Murayama, S.; Tomita, T.; Goedert, M.; Scheres, S.; Hasegawa, M.
10.1101/2023.04.13.536725 — neuroscience — Posted on 2023-04-13
2419 Nectophore coordination and kinematics by physonect siphonophores
Strock, S.; Costello, J. H.; Daniels, J.; Katija, K.; Colin, S.
10.1101/2023.04.12.536580 — zoology — Posted on 2023-04-13
2421 Carcinoma-associated fibroblast-like tumor cells remodel the Ewing sarcoma tumor microenvironment
Wrenn, E. D.; Apfelbaum, A. A.; Rudzinski, E. R.; Deng, X.; Jiang, W.; Sud, S.; Van Noord, R. A.; Newman, E. A.; Garcia, N. M.; Hoglund, V. J.; Bhise, S. S.; Kanaan, S. B.; Waltner, O. G.; Furlan, S. N.; Lawlor, E. R.
10.1101/2023.04.12.536619 — cancer biology — Posted on 2023-04-13
2422 Cancer heterogeneity is defined by normal cellular trade-offs
Weistuch, C.; Murgas, K. A.; Zhu, J.; Norton, L.; Dill, K. A.; Deasy, J. O.; Tannenbaum, A. R.
10.1101/2023.04.12.536595 — cancer biology — Posted on 2023-04-13
2424 Non-specific recognition of histone modifications by H3K9bhb antibody
Tsusaka, T.; Oses-Prieto, J. A.; Lee, C.; DeFelice, B.; Burlingame, A.; Goldberg, E. L.
10.1101/2023.04.12.536655 — biochemistry — Posted on 2023-04-13
2426 HIV reservoirs are dominated by genetically younger and clonally enriched proviruses
Kinloch, N. N.; Shahid, A.; Dong, W.; Kirkby, D.; Jones, B. R.; Beelen, C. J.; MacMillan, D. N.; Lee, G. Q.; Mota, T. M.; Sudderuddin, H.; Barad, E.; Harris, M.; Brumme, C. J.; Jones, R. B.; Brockman, M. A.; Joy, J. B.; Brumme, Z. L.
10.1101/2023.04.12.536611 — genetics — Posted on 2023-04-13
2429 Association between the skin microbiome and MHC class II diversity in an amphibian
Cortazar-Chinarro, M.; Richter-Boix, A.; Rodin-Morch, P.; Halvarsson, P.; Logue, J. B.; Hoglund, J.; Laurila, A.
10.1101/2023.04.12.536591 — evolutionary biology — Posted on 2023-04-13
2430 DNA-targeting and cell-penetrating antibody-drug conjugate
Shirali, A.; Dubljevic, V.; Cao, F.; Nishimura, R. N.; Ebens, A.; Campbell, J. A.; Hansen, J. E.
10.1101/2023.04.12.536500 — immunology — Posted on 2023-04-13
2432 Sidestream bio-P and mainstream anammox in a BNR process with upstream carbon capture
McCullough, K.; Klaus, S.; Wilson, C.; Vanrolleghem, P. A.; Gu, A. Z.; Bott, C. B.
10.1101/2023.04.11.536442 — systems biology — Posted on 2023-04-13
2437 A GH81-type β-glucan-binding protein facilitates colonization by mutualistic fungi in barley
Wanke, A.; van Boerdonk, S.; Mahdi, L. K.; Wawra, S.; Neidert, M.; Chandrasekar, B.; Saake, P.; Saur, I. M. L.; Derbyshire, P.; Holton, N.; Menke, F. L. H.; Brands, M.; Pauly, M.; Acosta, I. F.; Zipfel, C.; Zuccaro, A.
10.1101/2023.04.12.536646 — plant biology — Posted on 2023-04-13
2438 FGF-21 Conducts a Liver-Brain-Kidney Axis to Promote Renal Cell Carcinoma
Li, Z.; Zhang, X.; Zhu, W.; Zhang, C.; Sadak, K.; Halberstam, A. A.; Brown, J. R.; Perry, C. J.; Bunn, A.; Braun, D. A.; Adeniran, A.; Lee, S.; Wang, A.; Perry, R. J.
10.1101/2023.04.12.536558 — physiology — Posted on 2023-04-13
2443 GTP signaling links metabolism, DNA repair, and responses to genotoxic stress
Zhou, W.; Zhao, Z.; Lin, A.; Yang, J.; Xu, J.; Wilder-Romans, K.; Yang, A.; Li, J.; Solanki, S.; Speth, J.; Walker, N.; Scott, A. J.; Kothari, A. U.; Yao, Y.; Peterson, E. R.; Korimerla, N.; Werner, C. K.; Liang, J.; Jacobson, J.; Palavalasa, S.; Obrien, A.; Elaimy, A. L.; Ferris, S. P.; Zhao, S. G.; Sarkaria, J. N.; Gyorrfy, B.; Zhang, S.; Wajd, A.-H.; Umemura, Y.; Morgan, M. A.; Lawrence, T. S.; Lyssiotis, C. A.; Peters-Golden, M.; Shah, Y. M.; Wahl, D. R.
10.1101/2023.04.12.536297 — cancer biology — Posted on 2023-04-13
2444 Ion-mediated condensation controls the mechanics of mitotic chromosomes
Witt, H.; Harju, J.; Chameau, E. M.; Bruinsma, C. M.; Clement, T. V.; Nielsen, C. F.; Hickson, I. D.; Peterman, E. J.; Broedersz, C. P.; Wuite, G. J.
10.1101/2023.04.11.536423 — biophysics — Posted on 2023-04-13
2445 New paradigms in actomyosin energy transduction: critical evaluation of non-traditional models for orthophosphate release
Mansson, A.; Usaj, M.; Moretto, L.; Matusovsky, O. S.; Velayuthan, L. P.; Friedmann, R.; Rassier, D. E.
10.1101/2023.04.12.535196 — biophysics — Posted on 2023-04-13
2448 Flexibility and sensitivity in gene regulation out of equilibrium
Mahdavi, S.; Salmon, G. L.; Daghlian, P.; Garcia, H. G.; Phillips, R.
10.1101/2023.04.11.536490 — biophysics — Posted on 2023-04-13
2451 Automated Protein Affinity Optimization using a 1D-CNN Deep Learning Model
McWhirter, J. L.; Mukhopadhyay, A.; Farber, P.; Lakatos, G.; Dixit, S.
10.1101/2023.04.12.536512 — bioengineering — Posted on 2023-04-13
2452 Biology of Coital Behavior: Looking Through the Lens of Mathematical Genomics
Sil, M.; Nawn, D.; Hassan, S. S.; Chakraborty, S.; Goswami, A.; Basu, P.; Roopesh, L.; Wu, E.; Lundstrom, K.; Uversky, V. N.
10.1101/2023.04.12.536521 — genomics — Posted on 2023-04-13
2453 ME-Bayes SL: Enhanced Bayesian Polygenic Risk Prediction Leveraging Information across Multiple Ancestry Groups
Jin, J.; Zhan, J.; Zhang, J.; Zhao, R.; O'Connell, J.; Jiang, Y.; 23andMe Research Team, ; Buyske, S.; Gignoux, C. R.; Haiman, C. A.; Kenny, E.; Kooperberg, C.; North, K. E.; Koelsch, B. L.; Wojcik, G. L.; Zhang, H.; Chatterjee, N.
10.1101/2023.04.12.536510 — genetics — Posted on 2023-04-13
2457 Identification of differentially recognized T cell epitopes in the spectrum of Mtb infection
Panda, S.; Morgan, J.; Cheng, C.; Saito, M.; Gilman, R. H.; Ciobanu, N.; Crudu, V.; Catanzaro, D. G.; Catanzaro, A.; Rodwell, T.; Perera, J. S.; Chathuranga, T.; Gunasena, B.; DeSilva, A. D.; Peters, B.; Sette, A.; Lindestam Arlehamn, C. S.
10.1101/2023.04.12.536550 — immunology — Posted on 2023-04-13
2458 Dietary protein shapes the profile and repertoire of intestinal CD4+ T cells
Lockhart, A.; Reed, A.; de Castro, T. B. R.; Herman, C.; Canesso, M. C. C.; Mucida, D.
10.1101/2023.04.11.536475 — immunology — Posted on 2023-04-13
2461 Cancer Immunotherapy through Tissue Adhering Polymers
Borthwick, N. J.; Maikawa, C. L.; Weller, S.; Andresen, T. L.; Hansen, A. E.; Autzen, A. A. A.
10.1101/2023.03.23.533909 — cancer biology — Posted on 2023-04-13
2462 Engineering GliaTrap: a biodegradable non-swelling hydrogel with tuned release of CXCL12 to attract migrating glioblastoma cells
Suita, Y.; Miriyala, S.; Merih-Toruner, D.; Yue, W.; Xie, L.; Akobundu, B.; Perch, N.; Fiser, A.; Fajardo, E.; Shen, J.; Tapinos, N.
10.1101/2023.04.12.536581 — cancer biology — Posted on 2023-04-13
2463 Conformational dynamics of lipid transfer domains provide a general framework to decode their functional mechanism.
Srinivasan, S.; DiLuca, A.; Peter, A. T. J.; Gehin, C.; Lone, M. A.; Hornemann, T. A.; D'Angelo, G.; Vanni, S.
10.1101/2023.04.11.536463 — biophysics — Posted on 2023-04-13
2468 PGSbuilder: An end-to-end platform for human genome association analysis and polygenic risk score predictions
Lee, K.-H.; Lee, Y.-L.; Hsieh, T.-T.; Chang, Y.-C.; Wang, S.-S.; Fann, G.-Z.; Lin, W.-C.; Chen, T.-F.; Li, P.-H.; Kuo, Y.-L.; Chen, P.-L.; Juan, H.-F.; Tsai, H.-K.; Chen, C.-Y.; Huang, J.-H.
10.1101/2023.04.12.536584 — bioinformatics — Posted on 2023-04-13
2470 Optimal HLA imputation of admixed population with dimension reduction
Douillard, V.; dos Santos Brito Silva, N.; Bourguiba-Hachemi, S.; Naslavsky, M. S.; Scliar, M. O.; Duarte, Y. A. O.; Zatz, M.; Passos-Bueno, M. R.; Limou, S.; Gourraud, P.-A.; Launay, E.; Castelli, E. C.; SNP-HLA Reference Consortium (SHLARC), ; Vince, N.
10.1101/2023.04.12.536582 — genomics — Posted on 2023-04-13
2472 Universal baleen whale microsatellite panel for individual identification and power to detect parentage
Suarez-Menedez, M.; Berube, M.; Bachmann, L.; Best, P.; Heide-Jorgensen, M. P.; Lesage, V.; Oosting, T.; Prieto, R.; Ramp, C.; Robbins, J.; Sears, R.; Silva, M. A.; Tollis, M.; Vermeulen, E.; Vikingsson, G. A.; Wiig, O.; Palsboll, P. J.
10.1101/2023.04.12.536337 — genetics — Posted on 2023-04-13
2473 Deletion of Pax1 scoliosis-associated regulatory elements leads to a female-biased tail abnormality
Ushiki, A.; Sheng, R. R.; Zhang, Y.; Zhao, J.; Nobuhara, M.; Murray, E.; Ruan, X.; Rios, J. J.; Wise, C. A.; Ahituv, N.
10.1101/2023.04.12.536497 — genetics — Posted on 2023-04-13
2477 Genetic sex determination in three closely related hydrothermal vent gastropods, one of which has intersex individuals
Castel, J.; Pradillon, F.; Cueff, V.; Daguin-Thiebaut, C.; Ruault, S.; Mary, J.; Hourdez, S.; Jollivet, D.; Broquet, T.
10.1101/2023.04.11.536409 — evolutionary biology — Posted on 2023-04-13
2479 Impact of repeated short light exposures on sustained pupil responses in an fMRI environment
Beckers, E.; Campbell, I.; Sharifpour, R.; Paparella, I.; Berger, A.; Balda, F.; Koshmanova, E.; Mortazavi, N.; Talwar, P.; Sherif, S.; Jacobs, H.; Vandewalle, G.
10.1101/2023.04.12.536600 — neuroscience — Posted on 2023-04-13
2481 Transcriptomic and metabolomic characterization of antibacterial activity of Melastoma dodecandrum
Poh, W. H.; Ruhazat, N. S.; Yang, L. K.; Shivhare, D.; Lim, P. K.; Kanagasundaram, Y.; Rice, S. A.; Mutwil, M.
10.1101/2023.04.10.536307 — plant biology — Posted on 2023-04-13
2482 Reduced male fertility of an Antarctic mite following extreme heat stress could prompt localized population declines
Benoit, J. B.; Finch, G.; Ankrum, A. L.; Niemantsverdriet, J.; Paul, B.; Kelley, M.; Gantz, J. D.; Lee, R. E.; Denlinger, D. L.
10.1101/2023.04.11.535735 — physiology — Posted on 2023-04-13
2485 Ensemble-GNN: federated ensemble learning with graph neural networks for disease module discovery and classification
Pfeifer, B.; Chereda, H.; Martin, R.; Saranti, A.; Clemens, S.; Hauschild, A.-C.; Beissbarth, T.; Holzinger, A.; Heider, D.
10.1101/2023.03.22.533772 — bioinformatics — Posted on 2023-04-13
2486 Analysis of SARS-CoV-2 Recombinant Lineages XBC and XBC.1 in the Philippines and Evidence for Delta-Omicron Co-infection as a Potential Origin
Pangilinan, E. A. R.; Egana, J. M. C.; Mantaring, R. J. Q.; Telles, A. J. E.; Tablizo, F. A.; Lapid, C. M.; Yangzon, M. S. L.; Endozo, J. J. S.; Padilla, K. S. A. R.; Nipales, J. E.; Carandang, L. C. D. L.; Enriquez, Z. M. R.; Barot, T. A. U.; Manlimos, R. A.; Mangonon, K. N. P.; Plantig, M. E. L.; Araiza, S. M. M.; Llames, J.-H. S.; Punayan, K. P.; Serrano, R. P.; Drueco, A. M.; Lagnas, H. T.; Bistayan, P. A.; Aguilar, A. C.; Charisse Apo, J. G.; Austria, Y. V. D.; Bustamante, N. F. M.; Caelian, A. J. R.; Fernandez, R. E.; Galilea, X. A.; Gamboa, M. M.; Gervacio, C. J. A.; Mollejon, Z. V.; Pi
10.1101/2023.04.12.534029 — genetics — Posted on 2023-04-13
2489 Feedback information sharing in the human brain reflects bistable perception in the absence of report
Canales-Johnson, A.; Beerendonk, L.; Chennu, S.; Davidson, M. J.; Ince, R. A. A.; van Gaal, S.
10.1101/2021.11.02.466729 — neuroscience — Posted on 2023-04-13
2490 Impact of light on task-evoked pupil responses during cognitive tasks.
Campbell, I.; Beckers, E.; Sharifpour, R.; Berger, A.; Paparella, I.; Balda Aizpurua, J. F.; Koshmanova, E.; Mortazavi, N.; Sherif, S.; Vandewalle, G.
10.1101/2023.04.12.536570 — neuroscience — Posted on 2023-04-13
2491 Comprehensive Characterization of Endogenous Phospholamban Proteoforms Enabled by Photocleavable Surfactant and Top-down Proteomics
Rogers, H. T.; Roberts, D. S.; Larson, E. J.; Melby, J. A.; Rossler, K. J.; Carr, A. V.; Brown, K. A.; Ge, Y.
10.1101/2023.04.12.536120 — biochemistry — Posted on 2023-04-13
2494 Efficient self-organization of blastoids solely from mouse ESCs is facilitated by transient reactivation of 2C gene network
Jana, D.; Singh, P.; Sailasree, P.; Kumar, N.; Vijay, V.; Kale, H.; Lakshmi, J.; Kumari, A.; Sowpati, D. T.; Shekar, C.
10.1101/2023.04.12.536583 — developmental biology — Posted on 2023-04-13
2496 Unique proteomic signature of JCPyV-infected human astrocytes: from cells to extracellular vesicles
Oberholster, L.; Mathias, A.; Perriot, S.; Blaser, E.; Canales, M.; Jones, S.; Culebras, L.; Gimenez, M.; Kaynor, G. C.; Sapozhnik, A.; Richetin, K.; Goelz, S.; Du Pasquier, R.
10.1101/2023.04.11.536379 — neuroscience — Posted on 2023-04-13
2500 Spatial proteomics of human diabetic kidney disease, from health to class III
Kondo, A.; McGrady, M.; Nallapothula, D.; Ali, H.; Trevino, A. E.; Lam, A.; Preska, R.; D'Angio, H. B.; Wu, Z.; Lopez, L. N.; Badhesha, H. K.; Vargas, C. R.; Ramesh, A.; Wiegley, N.; Han, S. S.; Dall'Era, M.; Jen, K.-Y.; Mayer, A.; Afkarian, M.
10.1101/2023.04.12.534028 — molecular biology — Posted on 2023-04-13
2503 Severe Central Nervous System Demyelination in Sanfilippo Disease
Taherzadeh, M.; Zhang, E.; Londono, I.; Song, S.-K.; Wang, S.; Cooper, J. D.; Kennedy, T. E.; Morales, C. R.; Chen, Z.; Lodygensky, G. A.; Pshezhetsky, A. V.
10.1101/2023.04.12.536631 — neuroscience — Posted on 2023-04-12
2507 Disulfide bridge-dependent dimerization triggers FGF2 membrane translocation into the extracellular space
Lolicato, F.; Steringer, J.; Saleppico, R.; Beyer, D.; Fernandez-Sobaberas, J.; Unger, S.; Klein, S.; Riegerova, P.; Wegehingel, S.; Mueller, H.-M.; Freund, C.; Hof, M.; Sachl, R.; Chlanda, P.; Vattulainen, I.; Nickel, W.
10.1101/2023.04.12.536539 — biochemistry — Posted on 2023-04-12
2509 Large genetic variability of maize leaf palatability to european corn borer : metabolic insights
Sanane, I.; Nicolas, S.; Bauland, C.; Marion-Pol, F.; Nous, C.; Legrand, J.; Dillmann, C.
10.1101/2023.04.12.536551 — genetics — Posted on 2023-04-12
2510 Senescence-specific translation dysregulation desensitizes cells to stress by inhibiting activation of the integrated stress response
Payea, M. J.; Dar, S. A.; Anerillas, C. A.; Martindale, J. L.; Belair, C.; Munk, R.; Malla, S.; Fan, J.; Piao, Y.; Yang, X.; Rehman, A.; Banskota, N.; Abdelmohsen, K.; Gorospe, M.; Maragkakis, M.
10.1101/2023.04.12.536613 — molecular biology — Posted on 2023-04-12
2511 Capsules and their traits shape phage susceptibility and plasmid conjugation efficiency
Haudiquet, M.; Nucci, A.; Le Bris, J.; Bonnin, R. A.; Domingo-Calap, P.; Rendueles, O.; Rocha, E. P. C.
10.1101/2023.04.12.536574 — microbiology — Posted on 2023-04-12
2513 Learning from pre-pandemic data to forecast viral escape
Thadani, N. N.; Gurev, S.; Notin, P.; Youssef, N.; Rollins, N. J.; Sander, C.; Gal, Y.; Marks, D.
10.1101/2022.07.21.501023 — immunology — Posted on 2023-04-12
2519 Spatial proteomics of human diabetic kidney disease, from health to class III
Kondo, A.; McGrady, M.; Nallapothula, D.; Ali, H.; Trevino, A. E.; Lam, A.; Preska, R.; D'Angio, H. B.; Wu, Z.; Lopez, L. N.; Badhesha, H. K.; Vargas, C. R.; Ramesh, A.; Wiegley, N.; Han, S. S.; Dall'Era, M.; Jen, K.-Y.; Mayer, A.; Afkarian, M.
10.1101/2023.04.12.534028 — molecular biology — Posted on 2023-04-12
2520 Chromatin context-dependent regulation and epigenetic manipulation of prime editing
Li, X.; Chen, W.; Martin, B. K.; Calderon, D.; Lee, C.; Choi, J.; Chardon, F. M.; McDiarmid, T.; Kim, H.; Lalanne, J.-B.; Nathans, J. F.; Shendure, J.
10.1101/2023.04.12.536587 — molecular biology — Posted on 2023-04-12
2523 Plasmodium falciparum exploits CD44 as a co-receptor for erythrocyte invasion
Baro, B.; Kim, C. Y.; Lin, C.; Kongsomboonvech, A. K.; Tetard, M.; Salinas, N. D.; Tolia, N. H.; Egan, E. S.
10.1101/2023.04.12.536503 — microbiology — Posted on 2023-04-12
2526 Oligodendrocyte calcium signaling sculpts myelin sheath morphology
Iyer, M.; Kantarci, H.; Ambiel, N.; Novak, S. W.; Andrade, L. R.; Lam, M.; Munch, A. E.; Yu, X.; Khakh, B. S.; Manor, U. S.; Zuchero, J. B.
10.1101/2023.04.11.536299 — neuroscience — Posted on 2023-04-12
2528 An Azapeptide Platform in Conjunction with Covalent Warheads to Uncover High-Potency Inhibitors for SARS-CoV-2 Main Protease
Khatua, K.; Alugubelli, Y. R.; Yang, K.; Reddy, V.; Blankenship, L.; Coleman, D.; Atla, S.; Chaki, S.; Geng, Z.; Ma, X.; Xiao, J.; Chen, P.-H.; Cho, C.-C.; Vatansever, E. C.; Ma, Y.; Yu, G.; Neuman, B.; Xu, S.; Liu, W. R.
10.1101/2023.04.11.536467 — biochemistry — Posted on 2023-04-12
2529 G-quadruplexe as a structural modulator of Intron Retention upon viral infection
Lejault, P.; Terrier, M.-p.; Vannutelli, A.; Brand, C.; Bisaillon, M.; Perreault, J.-P.
10.1101/2023.04.12.536615 — biochemistry — Posted on 2023-04-12
2530 Activation and substrate specificity of the human P4-ATPase ATP8B1
Dieudonne, T.; Kummerer, F.; Juknaviciute Laursen, M.; Stock, C.; Kock Flygaard, R.; Khalid, S.; Lenoir, G.; Lyons, J. A.; Lindorff-Larsen, K.; Nissen, P.
10.1101/2023.04.12.536557 — biochemistry — Posted on 2023-04-12
2531 Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain
Harris, N. J.; Jenkins, M. L.; Nam, S.-E.; Rathinaswamy, M. K.; Parson, M. A.; Ranga-Prasad, H.; Dalwadi, U.; Moeller, B. E.; Sheeky, E.; Hansen, S. D.; Yip, C. K.; Burke, J. E.
10.1101/2023.04.12.536585 — biochemistry — Posted on 2023-04-12
2532 Analysis of SARS-CoV-2 Recombinant Lineages XBC and XBC.1 in the Philippines and Evidence for Delta-Omicron Co-infection as a Potential Origin
Pangilinan, E. A. R.; Egana, J. M. C.; Mantaring, R. J. Q.; Telles, A. J. E.; Tablizo, F. A.; Lapid, C. M.; Yangzon, M. S. L.; Endozo, J. J. S.; Padilla, K. S. A. R.; Nipales, J. E.; Carandang, L. C. D. L.; Enriquez, Z. M. R.; Barot, T. A. U.; Manlimos, R. A.; Mangonon, K. N. P.; Plantig, M. E. L.; Balucio, J. E. B.; Lustria, J. M. B.; Araiza, S. M. M.; Llames, J.-H. S.; Punayan, K. P.; Serrano, R. P.; Drueco, A. M.; Lagnas, H. T.; Bistayan, P. A.; Aguilar, A. C.; Charisse Apo, J. G.; Austria, Y. V. D.; Bustamante, N. F. M.; Caelian, A. J. R.; Fernandez, R. E.; Galilea, X. A.; Gamboa, M. M.; G
10.1101/2023.04.12.534029 — genetics — Posted on 2023-04-12
2534 Astrovirus replication is dependent on induction of double membrane vesicles through a PI3K-dependent, LC3-independent pathway
Bub, T.; Hargest, V.; Tan, S.; Smith, M.; Vazquez-Pagan, A.; Flerlage, T.; Brigleb, P. H.; Meliopoulos, V. A.; Lindenbach, B. D.; Cortez, V.; Crawford, J. C.; Schultz-Cherry, S.
10.1101/2023.04.11.536492 — microbiology — Posted on 2023-04-12
2535 Functional whole genome screen of nutrient-starved Mycobacterium tuberculosis identifies genes involved in antibiotic tolerance
Matern, W. M.; Harris, H. T.; Danchik, C.; McDonald, M.; Patel, G.; Srivastava, A.; Ioerger, T. R.; Bader, J.; Karakousis, P. C.
10.1101/2023.04.12.536593 — microbiology — Posted on 2023-04-12
2537 Evolution and Genetic Characterization of Seoul Virus in Wild Rats Rattus Norvegicus from an urban park in Lyon, France 2020-2022
Alburkat, H.; smura, t.; Bouilloud, M.; Pradel, J.; ANFRAY, G.; berthier, k.; Dutra, L.; loiseau, A.; Niamsap, T.; Olander, V.; sepulveda, d.; Venkat, V.; Charbonnel, N.; Castel, G.; Sironen, T.
10.1101/2023.04.12.536564 — microbiology — Posted on 2023-04-12
2542 CETP inhibitor evacetrapib enters mouse brain tissue
Phenix, J.; Cote, J.; Dieme, D.; Recinto, S. J.; Oestereich, F.; Efrem, S.; Haddad, S.; Bouchard, M.; Munter, L. M.
10.1101/2023.02.21.529381 — pharmacology and toxicology — Posted on 2023-04-12
2544 LENS - Landscape of Effective Neoantigens Software
Vensko, S. P.; Olsen, K.; Bortone, D. S.; Smith, C. C.; Chai, S.; Beckabir, W.; Fini, M.; Jadi, O.; Rubinsteyn, A.; Vincent, B.
10.1101/2022.04.01.486738 — cancer biology — Posted on 2023-04-12
2548 Identification of 1600 replication origins in S. cerevisiae
Foss, E. J.; Lichauco, C.; Gatbonton-Schwager, T.; Lofts, B.; Lao, U.; Bedalov, A.
10.1101/2023.04.11.536402 — genetics — Posted on 2023-04-12
2551 High-resolution cryo-electron microscopy of the human CDK-activating kinase for structure-based drug design
Cushing, V. I.; Koh, A. F.; Feng, J.; Jurgaityte, K.; Bahl, A. K.; Ali, S.; Kotecha, A.; Greber, B. J.
10.1101/2023.04.07.536029 — molecular biology — Posted on 2023-04-12
2552 Preterm birth accelerates the maturation of spontaneous and resting activity in the visual cortex
Witteveen, I.; McCoy, E.; Holsworth, T.; Shen, C.; Chang, W.; Nance, M.; Belkowitz, A.; Dougald, A.; Puglia, M.; Ribic, A.
10.1101/2023.01.20.524993 — neuroscience — Posted on 2023-04-12
2555 The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4,5-bisphosphate
Araya-Secchi, R.; Bugge, K.; Seiffert, P.; Petry, A.; Haxholm, G. W.; Lindorff-Larsen, K.; Pedersen, S. F.; Arleth, L.; Kragelund, B. B.
10.1101/2022.11.23.517650 — biophysics — Posted on 2023-04-12
2558 Modelling human KCNT1-epilepsy in Drosophila: a seizure phenotype and drug responses
Dibbens, L. M.; Ricos, M. G.; Hussain, R.; Shaukat, Z.; Lim, C. X.; Rychkov, G.; Islam, A.; Lippiat, J. D.; Caseley, E.
10.1101/2023.04.11.536495 — neuroscience — Posted on 2023-04-12
2559 Why flying insects gather at artificial light
Fabian, S. T.; Sondhi, Y.; Allen, P.; Theobald, J. C.; Lin, H.-T.
10.1101/2023.04.11.536486 — animal behavior and cognition — Posted on 2023-04-12
2560 TAR Syndrome-associated Rbm8a deficiency causes hematopoietic defects and attenuates Wnt/PCP signaling
Kocere, A.; Chiavacci, E.; Mendez-Acevedo, K. M.; Soneson, C.; Hiltabidle, M. S.; MacGowan, J. S.; Panakova, D.; Williams, M. L. K.; Robinson, M. D.; Mosimann, C.; Burger, A.
10.1101/2023.04.12.536513 — developmental biology — Posted on 2023-04-12
2561 Impact of light on task-evoked pupil responses during cognitive tasks.
Campbell, I.; Beckers, E.; Sharifpour, R.; Berger, A.; Paparella, I.; Balda Aizpurua, J. F.; Koshmanova, E.; Mortazavi, N.; Sherif, S.; Vandewalle, G.
10.1101/2023.04.12.536570 — neuroscience — Posted on 2023-04-12
2564 Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system
Datta, M. S.; Chen, Y.; Chauhan, S.; Zhang, J.; De La Cruz, E. D.; Gong, C.; Tomer, R.
10.1101/2023.04.12.536506 — neuroscience — Posted on 2023-04-12
2566 SorLA restricts TNFalpha release from microglia to shape glioma-supportive brain microenvironment
Kaminska, P.; Ovesen, P. L.; Jakiel, M.; Obrebski, T.; Schmidt, V.; Bieniek, M.; Anink, J.; Paterczyk, B.; Draminski, M.; Jensen, A. M. G.; Piatek, S.; Andersen, O. M.; Aronica, E.; Willnow, T. E.; Kaminska, B.; Dabrowski, M. J.; Malik, A. R.
10.1101/2023.04.12.536447 — neuroscience — Posted on 2023-04-12
2568 Color appearance of iridescent objects
Doerschner, K.; Ennis, R.; Boerner, P.; Maile, F. J.; Gegenfurtner, K.
10.1101/2023.04.12.535824 — neuroscience — Posted on 2023-04-12
2569 CB1R blockade unmasks TRPV1-mediated contextual fear generalization in female, but not male rats
Huckleberry, K. A.; Calitri, R.; Li, A. J.; Mejdell, M.; Singh, A.; Bhutani, V.; Laine, M. A.; Nastase, A. S.; Morena, M.; Hill, M.; Shansky, R. M.
10.1101/2023.04.12.536625 — neuroscience — Posted on 2023-04-12
2570 Evidence for Involvement of WDPCP Gene in Alcohol Consumption, Lipid Metabolism, and Liver Cirrhosis
OFarrell, F.; Aleyakpo, B.; Mustafa, R.; Jiang, X.; Pinto, R. C.; Elliott, P.; Tzoulaki, I.; Dehghan, A.; Loh, S. H. Y.; Barclay, J. W.; Martins, L. M.; Pazoki, R.
10.1101/2023.04.11.536418 — genetics — Posted on 2023-04-12
2571 Intracranial electroencephalography reveals effector-independent evidence accumulation dynamics in multiple human brain regions
Gherman, S.; Markowitz, N.; Tostaeva, G.; Espinal, E.; Mehta, A. D.; O'Connell, R. G.; Kelly, S. P.; Bickel, S.
10.1101/2023.04.10.536314 — neuroscience — Posted on 2023-04-12
2574 Differential neural circuit vulnerability to β-amyloid and tau pathologies in novel Alzheimer disease mice
Capilla-Lopez, M. D.; Deprada, A.; Andrade-Talavera, Y.; Martinez-Gallego, I.; Coatl-Cuaya, H.; Rodriguez-Alvarez, J.; Rodriguez-Moreno, A.; Parra-Damas, A.; Saura, C. A.
10.1101/2023.04.12.536603 — neuroscience — Posted on 2023-04-12
2575 Impact of repeated short light exposures on sustained pupil responses in an fMRI environment
Beckers, E.; Campbell, I.; Sharifpour, R.; Paparella, I.; Berger, A.; Balda, F.; Koshmanova, E.; Mortazavi, N.; Talwar, P.; Sherif, S.; Jacobs, H.; Vandewalle, G.
10.1101/2023.04.12.536600 — neuroscience — Posted on 2023-04-12
2576 Eupatilin improves cilia defects in human CEP290 ciliopathy models
Corral Serrano, J. C.; Sladen, P. E.; Ottaviani, D.; Rezek, O. F.; Jovanovic, K.; Athanasiou, D.; van der Spuy, J.; Mansfield, B. C.; Cheetham, M. E.
10.1101/2023.04.12.536565 — neuroscience — Posted on 2023-04-12
2578 Comparative Clustering (CompaCt) of eukaryote complexomes identifies novel interactions and sheds light on protein complex evolution
van Strien, J.; Evers, F.; Lutikurti, M.; Berendsen, S. L.; Garanto, A.; van Gemert, G.-J.; Cabrera-Orefice, A.; Rodenburg, R. J.; Brandt, U.; Kooij, T. W. A.; Huynen, M. A.
10.1101/2023.04.10.536322 — bioinformatics — Posted on 2023-04-12
2579 Annotation of the non-canonical translatome reveals that CHO cell microproteins are a new class of mAb drug product impurity
Castro-Rivadeneyra, M.; Tzani, I.; Kelly, P.; Strasser, L.; Guapo, F.; Tierney, C.; Chain, M.; Zhang, L.; Clynes, M.; Karger, B. L.; Barron, N.; Bones, J.; Clarke, C.
10.1101/2022.01.20.475618 — genomics — Posted on 2023-04-12
2580 A potential patient stratification biomarker for Parkinson's disease based on LRRK2 kinase-mediated centrosomal alterations in peripheral blood-derived cells
Naaldijk, Y.; Fernandez, B.; Fasiczka, R.; Fdez, E.; Leghay, C.; Croitoru, I.; Kwok, J. B.; Boulesnane, Y.; Vizeneux, A.; Mutez, E.; Calvez, C.; Destee, A.; Taymans, J.-M.; Vinagre Aragon, A.; Bergareche Yarza, A.; Padmanabhan, S.; Delgado, M.; Alcalay, R. N.; Chatterton, Z.; Dzamko, N.; Halliday, G.; Ruiz-Martinez, J.; Chartier-Harlin, M.-C.; Hilfiker, S.
10.1101/2023.04.11.536367 — neuroscience — Posted on 2023-04-12
2581 Modelling dementia in Drosophila uncovers shared and specific targets of TDP-43 proteinopathy across ALS and FTD relevant circuits
Godfrey, R. K.; Bjork, R. T.; Alsop, E.; Chauhan, B. S.; Ruvalcaba, H. C.; Antone, J.; Michael, A. F.; Williams, C.; Hala'ufia, G.; Blythe, A. D.; Hall, M.; Van Keuren-Jensen, K.; Zarnescu, D. C.
10.1101/2022.11.16.516763 — neuroscience — Posted on 2023-04-12
2582 TEAD1 regulates ITGA1 and ITGA2 to control prostate cancer progression
Cruz, S. P.; Zhang, Q.; Devarajan, R.; Paia, C.; Luo, B.; Zhang, K.; Xia, J.; Ahtikoski, A.; Vaarala, M. H.; Wenta, T.; Wei, G.-H.; Manninen, A.
10.1101/2023.04.12.536554 — cancer biology — Posted on 2023-04-12
2583 De-novo genome assembly of the invasive mosquito species Aedes japonicus and Aedes koreicus
Catapano, P. L.; Falcinelli, M.; Damiani, C.; Cappelli, A.; Koukouli, D.; Rossi, P.; Ricci, I.; Napolioni, V.; Favia, G.
10.1101/2023.04.12.534102 — genomics — Posted on 2023-04-12
2584 Identification of 1600 replication origins in S. cerevisiae
Foss, E. J.; Lichauco, C.; Gatbonton-Schwager, T.; Lofts, B.; Lao, U.; Bedalov, A.
10.1101/2023.04.11.536402 — genetics — Posted on 2023-04-12
2586 Comparison of commercially available differentiation media on morphology, function, and virus-host interaction in conditionally reprogrammed human bronchial epithelial cells
Awatade, N. T.; Reid, A. T.; Nichol, K. S.; Budden, K. F.; Veerati, P. C.; Pathinayake, P. S.; Grainge, C. L.; Hansbro, P. M.; Wark, P. A.
10.1101/2023.04.12.536514 — cell biology — Posted on 2023-04-12
2587 RAD52 prevents accumulation of Polalpha-dependent replication gaps at perturbed replication forks in human cells
Di Biagi, L.; Malacaria, E.; Aiello, F. A.; Valenzisi, P.; Marozzi, G.; Franchitto, A.; Pichierri, P.
10.1101/2023.04.12.536536 — cell biology — Posted on 2023-04-12
2589 Interspecies generation of functional muscle stem cells
Domenig, S. A.; Lenardic, A.; Zvick, J.; Tarnowska-Sengul, M.; Bundschuh, N.; Bacchin, G.; Ghosh, A.; Bar-Nur, O.
10.1101/2023.04.12.536533 — cell biology — Posted on 2023-04-12
2590 A gene-expression module in circulating immune cells is associated with cell migration during immune diseases.
Laurent, T.; Sinha, D.; Fourgeux, C.; Letellier, T.; Ville, S.; Bouchet-Delbos, L.; Branchereau, J.; Kerleau, C.; Brouard, S.; Blancho, G.; Giral, M.; Degauque, N.; Roquilly, A.; Josien, R.; Danger, R.; Poschmann, J.
10.1101/2023.04.11.536347 — immunology — Posted on 2023-04-12
2592 Cryo-EM structure of the human cardiac myosin filament
Dutta, D.; Nguyen, V.; Campbell, K.; Padron, R.; Craig, R.
10.1101/2023.04.11.536274 — biophysics — Posted on 2023-04-12
2596 DiscoGen: Learning to Discover Gene Regulatory Networks
Ke, N. R.; Dunn, S.-J.; Bornschein, J.; Chiappa, S.; Rey, M.; Lespiau, J.-B.; Cassirer, A.; Wang, J.; Weber, T.; Barrett, D.; Botvinick, M.; Goyal, A.; Mozer, M.; Rezende, D.
10.1101/2023.04.11.536361 — genomics — Posted on 2023-04-12
2597 Highly sensitive spatial transcriptomics using FISHnCHIPs of multiple co-expressed genes
ZHOU, X.; SEOW, W. Y.; Ha, N.; Cheng, T. H.; Jiang, L.; Boonruangkan, J.; Goh, J. J. L.; Prabhakar, S.; Chou, N.; Chen, K. H.
10.1101/2023.04.11.536345 — genomics — Posted on 2023-04-12
2601 ARDitox: platform for the prediction of TCRs potential off-target binding
Murcia Pienkowski, V.; Boschert, T.; Skoczylas, P.; Sanecka-Duin, A.; Jasinski, M.; Krol-Jozaga, B.; Mazzocco, G.; Stachura, S.; Bunse, L.; Kaczmarczyk, J.; Green, E. W.; Blum, A.
10.1101/2023.04.11.536336 — immunology — Posted on 2023-04-12
2603 LabEmbryoCam: An opensource phenotyping system for developing aquatic animals
Ibbini, Z.; Bruning, M.; Alili, S.; Holmes, L.; Tully, E.; McCoy, J.; Spicer, J. I.; Tills, O.
10.1101/2023.04.11.536373 — systems biology — Posted on 2023-04-12
2604 Myosin in autoinhibited off state(s), stabilized by mavacamten, can be recruited via inotropic effectors
Ma, W.; del Rio, C. L.; Qi, L.; Prodanovic, M.; Mijailovich, S.; Zambataro, C.; Gong, H.; Shimkunas, R.; Gollapudi, S.; Nag, S.; Irving, T.
10.1101/2023.04.10.536292 — physiology — Posted on 2023-04-12
2606 Reducing the mitochondrial oxidative burden alleviates lipid-induced insulin resistance in human skeletal muscle
Fiorenza, M.; Onslev, J.; Henriquez-Olguin, C.; Jensen, T. E.; Wojtaszewski, J. F. P.; Hostrup, M.; Bangsbo, J.
10.1101/2023.04.10.535538 — physiology — Posted on 2023-04-12
2607 Inhibition of somatostatin enhances the long-term metabolic outcomes of sleeve gastrectomy in mice
Kleiman, D.; Arad, Y.; Azulai, S.; Baker, A.; Bergel, M.; Elad, A.; Hefetz, L.; Israeli, H.; Littor, M.; Permyakova, A.; Samuel, I.; Tam, J.; Ben-Haroush Schyr, R.; Ben-Zvi, D.
10.1101/2023.04.11.536368 — physiology — Posted on 2023-04-12
2612 Maturation-dependent changes in the structure and seeding capacity of Aβ42 amyloid fibrils
Miller, A. M.; Chia, S.; Klimont, E.; Knowles, T.; Vendruscolo, M.; Ruggeri, F. S.
10.1101/2023.04.11.536374 — biophysics — Posted on 2023-04-12
2613 Alignment of spatial transcriptomics data using diffeomorphic metric mapping
Clifton, K.; Anant, M.; Aimiuwu, O. K.; Kebschull, J. M.; Miller, M. I.; Tward, D.; Fan, J.
10.1101/2023.04.11.534630 — bioinformatics — Posted on 2023-04-12
2614 Intravital Two-Photon Microscopy of the Native Thymus
Seyedhassantehrani, N.; Burns, C. S.; Verrinder, R.; Okafor, V.; Abbasizadeh, N.; Spencer, J. A.
10.1101/2023.04.10.536267 — bioengineering — Posted on 2023-04-12
2618 Immunoproteasomal Processing of Isolevuglandin Adducts in Hypertension
de la Visitacion, N.; Chen, W.; Krishnan, J.; Van Beusecum, J. P.; Amarnath, V.; Hennen, E. M.; Zhao, S.; Saleem, M.; Ao, M.; Harrison, D. G.; Patrick, D. M.
10.1101/2023.04.10.536054 — immunology — Posted on 2023-04-12
2619 Optogenetic-Induced Muscle Loading Leads to Mechanical Adaptation of the Achilles Tendon Enthesis in Mice
Ganji, E.; Lamia, S. N.; Stepanovich, M.; Whyte, N.; Goulet, R. W.; Abraham, A. C.; Killian, M. L.
10.1101/2023.04.11.536376 — bioengineering — Posted on 2023-04-12
2621 Caecilian genomes reveal molecular basis of adaptation and convergent evolution of limblessness in snakes and caecilians.
Ovchinnikov, V.; Uliano-Silva, M.; Wilkinson, M.; Wood, J.; Smith, M.; Oliver, K.; Sims, Y.; Torrance, J.; Suh, A.; McCarthy, S.; Durbin, R.; O'Connell, M. J.
10.1101/2022.02.23.481419 — evolutionary biology — Posted on 2023-04-12
2622 Ubiquitin-like cGAS chain formation by a super enzyme activates anti-phage response
Yan, Y.; Xiao, J.; Huang, F.; Yu, B.; Cheng, R.; Wu, H.; Lu, X.; Wang, X.; Oyejobi, G. K.; Robinson, C. V.; Wu, H.; Wu, D.; Wang, L.; Zhu, B.
10.1101/2022.05.25.493364 — microbiology — Posted on 2023-04-12
2625 A community driven GWAS summary statistics standard
Hayhurst, J.; Buniello, A.; Harris, L.; Mosaku, A.; Chang, C.; Gignoux, C. R.; Hatzikotoulas, K.; Karim, M. A.; Lambert, S. A.; Lyon, M.; McMahon, A.; Okada, Y.; Pirastu, N.; Rayner, N. W.; Schwartzentruber, J.; Vaughan, R.; Verma, S.; Wilder, S. P.; Cunningham, F.; Hindorff, L.; Wiley, K.; Parkinson, H.; Barroso, I.
10.1101/2022.07.15.500230 — bioinformatics — Posted on 2023-04-12
2627 Legacy effects of precipitation and land use impact maize growth and microbiome assembly under drought stress
Swift, J. F.; Kolp, M. R.; Carmichael, A.; Ford, N. E.; Hansen, P. M.; Sikes, B. A.; Kleiner, M.; Wagner, M. R.
10.1101/2023.04.11.536405 — plant biology — Posted on 2023-04-12
2633 Frizzled2 receives the WntA morphogen during butterfly wing pattern formation
Hanly, J. J.; Loh, L. S.; Mazo-Vargas, A.; Rivera-Miranda, T. S.; Livraghi, L.; Tendolkar, A.; Day, C. R.; Liutikaite, N.; Earls, E. A.; Corning, O. B.; D'Souza, N.; Hermina-Perez, J. J.; Mehta, C.; Ainsworth, J. A.; Rossi, M.; McMillan, W. O.; Perry, M. W.; Martin, A.
10.1101/2023.04.11.536469 — developmental biology — Posted on 2023-04-12
2634 Cooperative Motility, Force Generation and Mechanosensing in a Foraging Non-Photosynthetic Diatom
Zheng, P.; Kumadaki, K.; Quek, C.; Lim, Z. H.; Ashenafi, Y.; Yip, Z. T.; Newby, J.; Alverson, A. J.; Jedd, G.
10.1101/2023.03.27.533254 — cell biology — Posted on 2023-04-12
2635 Flowers are leakier than leaves but cheaper to build
Roddy, A.; Guilliams, M.; Fine, P.; Mambelli, S.; Dawson, T.; Simonin, K.
10.1101/2023.04.11.536372 — plant biology — Posted on 2023-04-12
2638 Physcomitrium patens SMXL homologs are PpMAX2-dependent negative regulators of growth
Guillory, A.; Lopez-Obando, M.; Bouchenine, K.; Le Bris, P.; Lecureuil, A.; Pillot, J.-P.; Steinmetz, V.; Boyer, F.-D.; Rameau, C.; de Saint Germain, A.; Bonhomme, S.
10.1101/2023.04.11.536386 — plant biology — Posted on 2023-04-12
2639 Lattice-Boltzmann Modelling for Inertial Particle Microfluidics Applications -- A Tutorial Review
Owen, B.; Kechagidis, K.; Bazaz, S. R.; Enjalbert, R.; Essman, E.; Mallorie, C.; Mirghaderi, F.; Schaaf, C.; Thota, K.; Vernekar, R.; Zhou, Q.; Warkiani, M. E.; Stark, H.; Krueger, T.
10.1101/2023.04.10.536205 — biophysics — Posted on 2023-04-12
2640 Erythroid differentiation intensifies RNA mis-splicing in SF3B1-mutant myelodysplastic syndromes with ring sideroblasts
Moura, P. L.; Mortera-Blanco, T.; Hofman, I. J. F.; Todisco, G.; Kretzschmar, W. W.; Bjorklund, A.-C.; Creignou, M.; Hagemann-Jensen, M.; Ziegenhain, C.; Granados, D. C.; Barbosa, I.; Walldin, G.; Jansson, M.; Ashley, N.; Mead, A. J.; Lundin, V.; Dimitriou, M.; Yoshizato, T.; Woll, P. S.; Ogawa, S.; Sandberg, R.; Jacobsen, S. E. W.; Hellstrom-Lindberg, E.
10.1101/2023.04.11.536355 — cancer biology — Posted on 2023-04-12
2642 Comparative Clustering (CompaCt) of eukaryote complexomes identifies novel interactions and sheds light on protein complex evolution
van Strien, J.; Evers, F.; Lutikurti, M.; Berendsen, S. L.; Garanto, A.; van Gemert, G.-J.; Cabrera-Orefice, A.; Rodenburg, R. J.; Brandt, U.; Kooij, T. W. A.; Huynen, M. A.
10.1101/2023.04.10.536322 — bioinformatics — Posted on 2023-04-12
2643 SpatialCTD: a large-scale TME spatial transcriptomic dataset to evaluate cell type deconvolution for immuno-oncology
Ding, J.; Venegas, J.; Lu, Q.; Wang, Y.; Wu, L.; Jin, W.; Wen, H.; Liu, R.; Tang, W.; Li, Z.; Zuo, W.; Chang, Y.; Lei, Y.; Danaher, P.; Xie, Y.; Tang, J.
10.1101/2023.04.11.536333 — bioinformatics — Posted on 2023-04-12
2647 Human pluripotent stem cells-derived Inner ear organoids recapitulate otic development in vitro.
Doda, D.; Alonso Jimenez, S.; Rehrauer, H.; Carreno, J. F.; Valsamides, V.; Di Santo, S.; Widmer, H. R.; Edge, A.; Locher, H.; van der Valk, W. H.; Zhang, J.; Koehler, K. R.; Roccio, M.
10.1101/2023.04.11.536448 — developmental biology — Posted on 2023-04-12
2649 Palmitoylethanolamide shows limited efficacy in controlling cerebral cryptococcosis in vivo
Munzen, M. E.; Reguera Gomez, M.; Hamed, M.; Enriquez, V.; Charles-Nino, C. L.; Dores, M. R.; Alvina, K.; Martinez, L. R.
10.1101/2023.04.10.536237 — microbiology — Posted on 2023-04-12
2651 An automated proximity proteomics pipeline for subcellular proteome and protein interaction mapping
Huttenhain, R.; Krogan, N. J.; Eckhardt, M.; von Zastrow, M.; Roth, B.; Foussard, H.; Marley, A.; Xu, J.; Vartak, R.; DiBerto, J. F.; Patil, T.; Polacco, B. J.; Zhong, X.; Li, Q.
10.1101/2023.04.11.536358 — systems biology — Posted on 2023-04-12
2653 Computational ranking-assisted identification of Plexin-B2 in homotypic and heterotypic clustering of circulating tumor cells in breast cancer metastasis
Schuster, E. J.; Dashzeveg, N. K.; Jia, Y.; Golam, K.; Zhang, T.; Hoffman, A. D.; Zhang, Y.; Zheng, C.; Ramos, E. K.; Taftaf, R.; El-Shennawy, L.; Scholten, D.; Adorno-Cruz, V.; Reduzzi, C.; Xu, R.; Siziopikou, K. P.; Plantanias, L. C.; Shah, A.; Gradishar, W.; Cristofanilli, M.; Tsai, C.-F.; Shi, T.; Liu, H.; Kitata, R. B.; Spahija, S.
10.1101/2023.04.10.536233 — cancer biology — Posted on 2023-04-12
2654 The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis
Coleman, J. C.; Tattersall, L.; Yianni, V.; Knight, L.; Yu, H.; Hallett, S.; Johnson, P.; Caetano, A. J.; Cosstick, C.; Ridley, A.; Gartland, A.; Conte, M. R.; Grigoriadis, A. E.
10.1101/2023.04.11.536377 — cancer biology — Posted on 2023-04-12
2655 Engrailed-1 Promotes Pancreatic Cancer Metastasis
Xu, J.; Roe, J. S.; Lee, E.; Tonelli, C.; Somerville, T.; Yao, M.; Milazzo, J.; Tiriac, H.; Kolarzyk, A.; Lee, E.; Grem, J.; Lazenby, A.; Grunkemeyer, J.; Hollingsworth, M.; Borowsky, A. D.; Park, Y.; Vakoc, C.; Tuveson, D.; Hwang, C.-i.
10.1101/2023.04.10.536259 — cancer biology — Posted on 2023-04-12
2657 Rewiring of master transcription factor cistromes during high-grade serous ovarian cancer development
Nameki, R.; Chang, H.; Yu, P. H.; Abbasi, F.; Lin, X.; Reddy, J.; Haro, M.; Fonseca, M.; Freedman, M. L.; Drapkin, R.; Corona, R.; Lawrenson, K.
10.1101/2023.04.11.536378 — cancer biology — Posted on 2023-04-12
2658 PITAR, a DNA damage-inducible Cancer/Testis long noncoding RNA, inactivates p53 by binding and stabilizing TRIM28 mRNA
Jana, S.; Mondal, M.; Mahale, S.; Gupta, B.; Prasasvi, K. R.; Kandasami, L.; Jha, N.; Chowdhury, A.; Santosh, V.; Kanduri, C.; Somasundaram, K.
10.1101/2023.04.11.536370 — cancer biology — Posted on 2023-04-12
2667 Nonlinearities and Timescales in Temporal Interference Stimulation
Plovie, T.; Schoeters, R.; Tarnaud, T.; Martens, L.; Joseph, W.; Tanghe, E.
10.1101/2022.02.04.479138 — neuroscience — Posted on 2023-04-12
2668 Working memory performance is tied to stimulus complexity
Pusch, R.; Packheiser, J.; Azizi, A. H.; Sevincik, C. S.; Rose, J.; Cheng, S.; Stuettgen, M. C.; Guentuerkuen, O.
10.1101/2021.09.10.459776 — neuroscience — Posted on 2023-04-12
2669 Transsynaptic labeling and transcriptional control of zebrafish neural circuits
Coomer, C.; Naumova, D.; Talay, M.; Zolyomi, B.; Snell, N.; Sorkac, A.; Chanchu, J.-M.; Cheng, J.; Roman, I.; Li, J.; Robson, D.; Barnea, G.; Halpern, M. E.
10.1101/2023.04.03.535421 — neuroscience — Posted on 2023-04-12
2670 MAP kinase ERK5 modulates cancer cell sensitivity to extrinsic apoptosis induced by death-receptor agonists and Natural Killer cells
Espinosa-Gil, S.; Ivanova, S.; Alari-Pahissa, E.; Denizli, M.; Villafranca-Magdalena, B.; Vinas-Casas, M.; Bolinaga-Ayala, I.; Gamez-Garcia, A.; Colas, E.; Lopez-Botet, M.; Zorzano, A.; Lizcano, J. M.
10.1101/2023.03.22.533738 — cancer biology — Posted on 2023-04-12
2673 Genome assembly of the hybrid grapevine Vitis Chambourcin
Patel, S.; Harris, Z. N.; Londo, J.; Miller, A.; Fennell, A.
10.1101/2023.01.18.524616 — bioinformatics — Posted on 2023-04-12
2674 Pangenome Graph Construction from Genome Alignment with Minigraph-Cactus
Hickey, G.; Monlong, J.; Ebler, J.; Novak, A.; Eizenga, J. M.; Gao, Y.; Human Pangenome Reference Consortium, ; Marschall, T.; Li, H.; Paten, B.
10.1101/2022.10.06.511217 — bioinformatics — Posted on 2023-04-12
2680 Embracing firefly flash pattern variability with data-driven species classification
Martin, O. L.; Nguyen, C.; Sarfati, R.; Chowdhury, M.; Iuzzolino, M. L.; Nguyen, D. M. T.; Layer, R. M.; Peleg, O.
10.1101/2023.03.08.531653 — ecology — Posted on 2023-04-12
2682 Plasmodium exoerythrocytic parasites redirect trafficking of human proteins to the parasitophorous vacuole
Calla, J.; Mittal, N.; LaMonte, G.; Liffner, B.; Godinez-Macias, K.; Carolino, K.; Walker, G. T.; Zou, B. Y.; Paytas, E.; Guerra, L.; Tong-Rios, C.; Campo, B.; Vinetz, J. M.; Gamboa, D.; Raffatellu, M.; Absalon, S.; Winzeler, E.
10.1101/2022.11.22.517223 — cell biology — Posted on 2023-04-12
2684 Temporal Dynamics of Genetically Heterogeneous Extended-Spectrum Cephalosporin Resistant Escherichia coli Bloodstream Infections
Shropshire, W. C.; Strope, B.; Selvaraj Anand, S.; Bremer, J.; McDaneld, P.; Bhatti, M. M.; Flores, A. R.; Kalia, A.; Shelburne, S. A.
10.1101/2023.02.07.527510 — microbiology — Posted on 2023-04-12
2685 The promiscuous development of an unconventional Qa1b-restricted T cell population
Manoharan Valerio, M. A.; Arana, K.; Guan, J.; Wei Chan, S.; Yang, X.; Kurd, N. S.; Lee, A.; Shastri, N.; Coscoy, L.; Robey, E.
10.1101/2022.09.26.509583 — immunology — Posted on 2023-04-12
2687 Dynamics of cortical contrast adaptation predict perception of signals in noise.
Angeloni, C. F.; Mlynarski, W.; Piasini, E.; Williams, A. M.; Wood, K. C.; Garami, L.; Hermundstad, A.; Geffen, M. N.
10.1101/2021.08.11.455845 — neuroscience — Posted on 2023-04-12
2689 Greengenes2 enables a shared data universe for microbiome studies
McDonald, D.; Jiang, Y.; Balaban, M.; Cantrell, K.; Zhu, Q.; Gonzalez, A.; Morton, J. T.; Nicolaou, G.; Parks, D.; Karst, S. M.; Albertsen, M.; Hugenholtz, P.; DeSantis, T.; Mirarab, S.; Song, S. J.; Bartko, A.; Havulinna, A. S.; Jousilahti, P.; Cheng, S.; Inouye, M.; Niiranen, T.; Jain, M.; Salomaa, V.; Lahti, L.; Knight, R.
10.1101/2022.12.19.520774 — bioinformatics — Posted on 2023-04-11
2691 A single-cell atlas of the free-living miracidium larva of Schistosoma mansoni
Attenborough, T.; Rawlinson, K. A.; Soria, C. L. D.; Ambridge, K.; Sankaranarayanan, G.; Graham, J.; Doyle, S. R.; Rinaldi, G.; Berriman, M.
10.1101/2023.03.27.533868 — genomics — Posted on 2023-04-11
2693 MAPT expression is mediated by long-range interactions with cis-regulatory elements
Rogers, B. B.; Anderson, A. G.; Lauzon, S. N.; Davis, M. N.; Hauser, R. M.; Roberts, S. C.; Rodriguez-Nunez, I.; Trausch-Lowther, K.; Barinaga, E. A.; Taylor, J. W.; Mackiewicz, M.; Roberts, B. S.; Cooper, S. J.; Rizzardi, L. F.; Myers, R. M.; Cochran, J. N.
10.1101/2023.03.07.531520 — genomics — Posted on 2023-04-12
2696 When cheating turns into a stabilizing mechanism of mutualistic networks
Duchenne, F.; Aubert, S.; Barreto, E.; Brenes, E.; Maglianesi, M. A.; Santander, T.; Guevara, E. A.; Graham, C. H.
10.1101/2023.03.31.533549 — ecology — Posted on 2023-04-12
2697 An introduction to predictive distribution modelling for conservation to welcome novel perspectives
MacPherson, M.; Burgio, K. R.; DeSaix, M.; Freeman, B.; Herbert, J.; Herman, R.; Jirinec, V.; Shonfield, J.; Slager, D.; van Rees, C.; Jankowski, J.
10.1101/2021.05.26.445867 — ecology — Posted on 2023-04-12
2698 Birth, cell fate and behavior of progenitors at the origin of the cardiac mitral valve
Fahrat, B.; Bordeu, I.; Jagla, B.; Blanc, H.; Loulier, K.; Simons, B. D.; Beaurepaire, E.; Livet, J.; Puceat, M.
10.1101/2022.08.06.503022 — developmental biology — Posted on 2023-04-12
2699 3D environment modulates persistent lamin distribution and the biomechanical signature of the nucleus.
Gonzalez-Novo, R.; Zamora Carreras, H.; De Lope-Planelles, A.; Lopez-Menendez, H.; Roda-Navarro, p.; Monroy, F.; Wang, L.; Toseland, C. P.; Redondo-Munoz, J.
10.1101/2023.04.10.536202 — cell biology — Posted on 2023-04-12
2702 Evolution within a given virulence phenotype (pathotype) is driven by changes in aggressiveness: a case study of French wheat leaf rust populations
FONTYN, C.; MEYER, K. J.; BOIXEL, A.-L.; DELESTRE, G.; PIAGET, E.; PICARD, C.; SUFFERT, F.; MARCEL, T. C.; GOYEAU, H.
10.1101/2022.08.29.505401 — microbiology — Posted on 2023-04-12
2703 Voltammetry in the spleen assesses real-time anti-inflammatory norepinephrine release elicited by autonomic neurostimulation
Mughrabi, I. T.; Gerber, M.; Jayaprakash, N.; Palandira, S. P.; Al-Abed, Y.; Datta-Chaudhuri, T.; Smith, C.; Pavlov, V. A.; Zanos, S.
10.1101/2022.04.26.489592 — neuroscience — Posted on 2023-04-11
2706 Distinct beta frequencies reflect categorical decisions
Rassi, E.; Zhang, Y.; Mendoza, G.; Mendez, J. C.; Merchant, H.; Haegens, S.
10.1101/2022.10.17.512497 — neuroscience — Posted on 2023-04-11
2707 Regional vulnerability in a neurodegenerative disease: Delineating SCA1 CNS and muscle therapeutic targets using a conditional mutant ATXN1 mouse
Duvick, L.; Southern, W. M.; Benzow, K.; Handler, H. P.; Mitchell, J. S.; Kuivinen, H.; Gadiparthi, U. K.; Yang, P.; Soles, A.; Scheeler, C.; Rainwater, O.; Serres, S.; Larson, E.; Nichols-Meade, T.; You, Y.; Zoghbi, H. Y.; Ervasti, J. M.; Cvetanovic, M.; Koob, M. D.; Orr, H. T.
10.1101/2023.02.08.527710 — neuroscience — Posted on 2023-04-11
2709 Trends in self-citation rates in Neuroscience literature
Rosenblatt, M.; Mehta, S.; Peterson, H.; Dadashkarimi, J.; Rodriguez, R. X.; Foster, M. L.; Adkinson, B. D.; Liang, Q.; Kimble, V. M.; Ye, J.; McCusker, M. C.; Farruggia, M. C.; Rolison, M.; Westwater, M. L.; Jiang, R.; Noble, S.; Scheinost, D.
10.1101/2022.09.27.509533 — neuroscience — Posted on 2023-04-11
2711 Calcineurin inhibitor nephrotoxicity revisited: perspectives emerging from differential impact on renal compartments
Demirci, H.; Popovic, S.; Dittmayer, C.; Yilmaz, D. E.; El-Shimy, I. A.; Mülleder, M.; Hinze, C.; Mutig, K.; Bachmann, S.
10.1101/2023.04.05.535688 — pathology — Posted on 2023-04-11
2712 Cristae formation is a mechanical buckling event controlled by the inner membrane lipidome
Venkatraman, K.; Lee, C. T.; Garcia, G. C.; Mahapatra, A.; Perkins, G.; Kim, K.-Y.; Pasolli, H. A.; Phan, S.; Lippincott-Schwartz, J.; Ellisman, M.; Rangamani, P.; Budin, I.
10.1101/2023.03.13.532310 — biophysics — Posted on 2023-04-11
2715 Long-term evolution of proliferating yeast cells using the eVOLVER platform
Garcia-Ruano, D.; Jain, A.; Heins, Z. J.; Wong, B. G.; Wolle, E. Y.; Khalil, A. S.; Coudreuse, D.
10.1101/2023.03.28.534552 — evolutionary biology — Posted on 2023-04-11
2716 DNA Repair Function Scores for 2172 Variants in the BRCA1 Amino-Terminus
Diabate, M.; Islam, M. M.; Nagy, G.; Banerjee, T.; Dhar, S.; Smith, N.; Adamovich, A. I.; Starita, L. M.; Parvin, J. D.
10.1101/2023.04.10.536331 — cancer biology — Posted on 2023-04-11
2717 Dimerisation of European robin cryptochrome 4a
Hanic, M.; Antill, L. M.; Gehrckens, A. S.; Schmidt, J.; Gortemaker, K.; Bartolke, R.; El-Baba, T. J.; Xu, J.; Koch, K. W.; Mouritsen, H.; Benesch, J. L.; Hore, P. J.; Solov'yov, I. A.
10.1101/2023.04.11.536350 — biochemistry — Posted on 2023-04-11
2720 Targeting ABCB4 using mRNA-LNP for the treatment of rare liver diseases
Alsuraih, M.; LaViolette, B. M.; Lin, G.-Y.; Kovi, R.; Daurio, N.; Cheng, C.; Ahn, Y.; Sun, X.; Jiang, Z.; Wang, Y.; Li, S.; Cheng, Y.; Fan, X.; Haskins, J.; Ortiz, R.; Hunter, A.; Hirenallur Shanthappa, D.; Wu, Y.; Holsti, M.; Stewart, M.; Tadin Strapps, M.; Chiang, S.-H.
10.1101/2023.04.11.535868 — molecular biology — Posted on 2023-04-11
2721 The anti-cancer compound JTE-607 reveals hidden sequence specificity of the mRNA 3' processing machinery
Liu, L.; Yu, A. M.; Wang, X.; Soles, L. V.; Chen, Y.; Yoon, Y.; Sarkan, K. S. K.; Valdez, M. C.; Linder, J.; Marazzi, I.; Yu, Z.; Qiao, F.; Li, W.; Seelig, G.; Shi, Y.
10.1101/2023.04.11.536453 — molecular biology — Posted on 2023-04-11
2729 Computationally Engineered CRISPR-SpyCas9 High-Fidelity Variants with Improved Specificity and Reduced Non-specific DNA Damage
Rabinowitz, R.; Shor, O.; Zerbib, J.; Herman, S.; Zelikson, N.; Madiwale, S.; Yom-Tov, N.; Ben-David, U.; Benninger, F.; Offen, D.
10.1101/2023.04.11.536265 — bioengineering — Posted on 2023-04-11
2730 The Circulation of Metabolites in the Outer Retina
Hass, D. T.; Giering, E.; Bisbach, C. M.; Robbings, B. M.; Mundinger, T. O.; Hurley, J. B.
10.1101/2023.04.10.536306 — biochemistry — Posted on 2023-04-11
2732 In situ structures from relaxed cardiac myofibrils reveal the organization of the muscle thick filament
Tamborrini, D.; Wang, Z.; Wagner, T.; Tacke, S.; Stabrin, M.; Grange, M.; Kho, A. L.; Rees, M.; Bennett, P.; Gautel, M.; Raunser, S.
10.1101/2023.04.11.536387 — biochemistry — Posted on 2023-04-11
2734 Cooperative dynamics of DNA grafted magnetic nanoparticles optimize magnetic biosensing and coupling to DNA origami
Lak, A.; Wang, Y.; Kolbeck, P. J.; Pauer, C.; Chowdhury, M. S.; Cassani, M.; Ludwig, F.; Viereck, T.; Selbach, F.; Tinnefeld, P.; Schilling, M.; Liedl, T.; Tavacoli, J.; Lipfert, J.
10.1101/2023.04.11.536349 — biochemistry — Posted on 2023-04-11
2742 A bioorthogonal antibody-based chemically-induced-dimerization switch for therapeutic application
Martinko, A. J.; Tran, H. L.; Simonds, E. F.; Cooke, A. L.; Huang, Z.; Raguveer, S.; Agullet, J. P.; Prasad, S.; Going, C.; Marshall, L.; Park, T.; Banerjee, S.; Macdonald, R.; Jian, M.; Ng, K.; Palakodaty, A.; Kaur, M.; Ponce, A.; Tabrizi, M.; Hill, Z. B.
10.1101/2023.04.11.536272 — synthetic biology — Posted on 2023-04-11
2743 Non-Human Peptides Revealed in Blood Reflect the Composition of Small Intestine Microbiota
Arapidi, G. P.; Urban, A. S.; Osetrova, M. S.; Shender, V. O.; Butenko, I. O.; Bukato, O. N.; Kuznetsov, A. A.; Saveleva, T. M.; Nos, G. A.; Ivanova, O. M.; Lopukhov, L. V.; Laikov, A. V.; Sharova, N. I.; Nikonova, M. F.; Mitin, A. N.; Martinov, A. I.; Grigorieva, T. V.; Ilina, E. N.; Ivanov, V. T.; Govorun, V. M.
10.1101/2023.04.11.536435 — biochemistry — Posted on 2023-04-11
2745 Contribution of cortical layers to human dynamic functional connectivity
Pais-Roldan, P.; Yun, S. D.; Ramkiran, S.; Veselinovic, T.; Neuner, I.; Zimmermann, M.; Felder, J.; Shah, J. N.
10.1101/2023.04.11.536354 — neuroscience — Posted on 2023-04-11
2747 An improved genome assembly of the saguaro cactus (Carnegiea gigantea (Engelm.) Britton & Rose).
Copetti, D.; Burquez, A.; Shimizu, K. K.; Wing, R. A.; Sanderson, M. J.; Wojciechowski, M. F.
10.1101/2023.04.11.536419 — genomics — Posted on 2023-04-11
2750 Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts
Arslan, F. N.; Hannezo, E.; Merrin, J.; Loose, M.; Heisenberg, C.-P.
10.1101/2023.04.11.536411 — cell biology — Posted on 2023-04-11
2752 A system of feed-forward cerebellar circuits that extend and diversify sensory signaling
Hariani, H. N.; Algstam, A. B.; Candler, C. T.; Witteveen, I. F.; Sidhu, J. K.; Balmer, T. S.
10.1101/2023.04.11.536335 — neuroscience — Posted on 2023-04-11
2756 Validation of σ2R/TMEM97 as a neuropathic pain target: Specificity, human expression and mechanism of action.
Yousuf, M. S.; Sahn, J. J.; David, E. T.; Shiers, S.; Royer, D. M.; Garcia, C. D.; Zhang, J.; Hong, V. M.; Ahmad, A.; Kolber, B. J.; Liebl, D. J.; Martin, S. F.; Price, T. J.
10.1101/2023.04.11.536439 — neuroscience — Posted on 2023-04-11
2757 Chromatin Reprogramming of In Vitro Fertilized and Somatic Cell Nuclear Transfer Bovine Embryos During Embryonic Genome Activation
Grow, E. J.; Liu, Y.; Fan, Z.; Perisse, I.; Patrick, T.; Regouski, M.; Shadle, S.; Polejaeva, I.; Cairns, B.; White, K.
10.1101/2023.04.10.536281 — developmental biology — Posted on 2023-04-11
2762 A shared pathogenic mechanism for valproic acid and SHROOM3 knockout in a brain organoid model of neural tube defects
Takla, T. N.; Luo, J.; Sudyk, R.; Huang, J.; Walker, J. C.; Vora, N. L.; Sexton, J. Z.; Parent, J. M.; Tidball, A. M.
10.1101/2023.04.11.536245 — neuroscience — Posted on 2023-04-11
2767 Oligodendrocyte calcium signaling regulates myelin sheath morphology
Iyer, M.; Kantarci, H.; Ambiel, N.; Novak, S. W.; Andrade, L. R.; Lam, M.; Munch, A. E.; Yu, X.; Khakh, B. S.; Manor, U. S.; Zuchero, J. B.
10.1101/2023.04.11.536299 — neuroscience — Posted on 2023-04-11
2768 The landscape of biomedical research
Gonzalez-Marquez, R.; Schmidt, L.; Schmidt, B. M.; Berens, P.; Kobak, D.
10.1101/2023.04.10.536208 — scientific communication and education — Posted on 2023-04-11
2769 A rapid and bidirectional reporter of neural activity reveals neural correlates of social behaviors in Drosophila
Bonheur, M.; Swartz, K. J.; Metcalf, M. G.; Zhukovskaya, A.; Mehta, A.; Connors, K. E.; Barasch, J. G.; Wen, X.; Jamieson, A. R.; Martin, K. C.; Axel, R.; Hattori, D.
10.1101/2023.04.10.536242 — neuroscience — Posted on 2023-04-11
2770 Divergent pattern of development in rats and humans.
Campos, W.; Iorii, T. A.; Presti, A.; Grimson, R.; Vazquez, P.
10.1101/2023.04.11.536227 — neuroscience — Posted on 2023-04-11
2772 Molecular profiling of high-level athlete skeletal muscle after acute exercise - a systems biology approach
Reitzner, S. M.; Emanuelsson, E. B.; Arif, M.; Kaczkowski, B.; Kwon, A. T.-J.; Mardinoglu, A.; Arner, E.; Chapman, M. A.; Sundberg, C. J.
10.1101/2023.04.11.535671 — physiology — Posted on 2023-04-11
2778 RTEL1 is required for silencing and epigenome stability
Olivier, M.; Hesketh, A.; Pouch-Pelissier, M.-N.; Pelissier, T.; Huang, Y.; Latrasse, D.; Benhamed, M.; Mathieu, O.
10.1101/2023.04.11.535823 — genomics — Posted on 2023-04-11
2779 Methane formation driven by light and heat prior to the origin of life
Ernst, L.; Barayeu, U.; Haedeler, J.; Dick, T. P.; Klatt, J. M.; Keppler, F.; Rebelein, J. G.
10.1101/2023.04.11.535677 — evolutionary biology — Posted on 2023-04-11
2780 ATP synthase evolution on a cross-braced dated tree of life
Mahendrarajah, T. A.; Moody, E. R. R.; Schrempf, D.; Szantho, L. L.; Dombrowski, N.; Davin, A. A.; Pisani, D.; Donoghue, P.; Szollosi, G. J.; Williams, T. A.; Spang, A.
10.1101/2023.04.11.536006 — evolutionary biology — Posted on 2023-04-11
2781 Tree diversity increases productivity through enhancing structural complexity across mycorrhizal types
Ray, T.; Delory, B.; Bruelheide, H.; Eisenhauer, N.; Ferlian, O.; Quosh, J.; Oheimb, G. v.; Fichtner, A.
10.1101/2023.04.11.536229 — ecology — Posted on 2023-04-11
2783 Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike protein
Waki, K.; Tani, H.; Saga, Y.; Shimada, T.; Yamazaki, E.; Koike, S.; Okada, N.; Isobe, M.; Kurosawa, N.
10.1101/2023.04.10.536311 — immunology — Posted on 2023-04-11
2784 Cellular Senescence is a Double-Edged Sword in Regulating Aged Immune Responses to Influenza
Torrance, B. L.; Panier, H. A.; Cadar, A. N.; Martin, D. E.; Lorenzo, E. C.; Jellison, E. R.; Bartley, J. M.; Haynes, L.
10.1101/2023.04.10.536027 — immunology — Posted on 2023-04-11
2787 Spatiotemporal Genomic Profiling of Intestinal Metaplasia Reveals Clonal Dynamics of Gastric Cancer Progression
Huang, K. K.; Ma, H.; Uchihara, T.; Sheng, T.; Chong, R. H. H.; Zhu, F.; Srivastava, S.; Tay, S. T.; Sundar, R.; Tan, A. L. K.; Ong, X.; Lee, M.; Ho, S. W. T.; Lesluyes, T.; Van Loo, P.; Chua, J. S.; Ramnarayanan, K.; Ang, T. L.; Khor, C.; Lee, J. W. J.; Tsao, S. K. K.; Teh, M.; Chung, H.; So, J. B. Y.; Yeoh, K. G.; Tan, P.
10.1101/2023.04.10.536195 — cancer biology — Posted on 2023-04-11
2790 Fecal metagenomics to identify biomarkers of food intake in healthy adults: Findings from randomized, controlled, nutrition trials
Shinn, L. M.; Mansharamani, A.; Baer, D. J.; Novotny, J. A.; Charron, C. S.; Khan, N. A.; Zhu, R.; Holscher, H. D.
10.1101/2023.04.10.536271 — bioinformatics — Posted on 2023-04-11
2793 Fully-primed slowly-recovering vesicles mediate presynaptic LTP at neocortical neurons
Weichard, I.; Taschenberger, H.; Gsell, F.; Bornschein, G.; Ritzau-Jost, A.; Schmidt, H.; Kittel, R. J.; Eilers, J.; Neher, E.; Hallermann, S.; Nerlich, J.
10.1101/2023.04.11.535831 — neuroscience — Posted on 2023-04-11
2794 Bento: A toolkit for subcellular analysis of spatial transcriptomics data
Mah, C. K.; Ahmed, N.; Lopez, N.; Lam, D.; Monell, A.; Kern, C.; Han, Y.; Prasad, G.; Cesnik, A. J.; Lundberg, E.; Zhu, Q.; Carter, H. W.; Yeo, G. W.
10.1101/2022.06.10.495510 — bioinformatics — Posted on 2023-04-11
2797 A Predictive Coding Model of the N400
Eddine, S. N.; Brothers, T. A.; Wang, L.; Spratling, M.; Kuperberg, G.
10.1101/2023.04.10.536279 — neuroscience — Posted on 2023-04-11
2798 Coexistence of state, choice, and sensory integration coding in barrel cortex LII/III
Garderes, P.-M.; Ganea, D. A.; Le Gal, S.; Rousseau, C. V.; Mamane, A.; Haiss, F.
10.1101/2023.04.10.536289 — neuroscience — Posted on 2023-04-11
2802 Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses
Lubow, J.; Levoir, L. M.; Ralph, D. K.; Belmont, L.; Contreras, M.; Cartwright-Acar, C. H.; Kikawa, C.; Kannan, S.; Davidson, E.; Doranz, B. J.; Duran, V.; Sanchez, D. E.; Sanz, A. M.; Rosso, F.; Einav, S.; Matsen, F. A.; Goo, L.
10.1101/2023.04.09.536175 — microbiology — Posted on 2023-04-11
2803 α-Melanocyte-Stimulating Hormone Regulates Pathological Cardiac Remodeling by Activating Melanocortin 5 Receptor in Cardiomyocytes
Suominen, A. M.; Saldo Rubio, G.; Ruohonen, S.; Szabo, Z.; Pohjolainen, L.; Ghimire, B.; Ruohonen, S. T.; Saukkonen, K.; Ijas, J.; Skarp, S.; Kaikkonen, L.; Cai, M.; Wardlaw, S. L.; Ruskoaho, H.; Talman, V.; Savontaus, E.; Kerkelä, R.; Rinne, P.
10.1101/2023.04.06.535956 — physiology — Posted on 2023-04-11
2804 A late Neanderthal reveals genetic isolation in their populations before extinction
Slimak, L.; Vimala, T.; Seguin-Orlando, A.; Metz, L.; Zanolli, C.; Joannes-Boyau, R.; Frouin, M.; Arnold, L. J.; Demuro, M.; Deviese, T.; Comeskey, D.; Buckley, M.; Camus, H.; Muth, X.; Lewis, J.; Bocherens, H.; Yvorra, P.; Tenailleau, C.; Duployer, B.; Coqueugniot, H.; Dutour, O.; Higham, T.; Sikora, M.
10.1101/2023.04.10.536015 — genomics — Posted on 2023-04-10
2806 Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics
Chan, T. F.; Rui, X.; Conti, D. V.; Fornage, M.; Graff, M.; Haessler, J.; Haiman, C.; Highland, H. M.; Jung, S. Y.; Kenny, E.; Kooperberg, C.; Le Marchland, L.; North, K. E.; Tao, R.; Wojcik, G.; Gignoux, C. R.; PAGE Consortium, ; Chiang, C. W.; Mancuso, N.
10.1101/2023.04.10.536252 — genetics — Posted on 2023-04-10
2813 Perirhinal Cortex Learns A Predictive Map of The Task Environment
Lee, D. G.; McLachlan, C. A.; Nogueira, R.; Kwon, O.; Carey, A.; House, G.; Lagani, G. D.; LaMay, D.; Fusi, S.; Chen, J. L.
10.1101/2023.03.17.532214 — neuroscience — Posted on 2023-04-10
2816 Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranes
Mudumbi, K. C.; Burns, E. A.; Schodt, D. J.; Petrova, Z. O.; Kiyatkin, A.; Kim, L. W.; Mangiacapre, E. M.; Ortiz-Caraveo, I.; Ortiz, H. R.; Hu, C.; Ashtekar, K. D.; Lidke, K. A.; Lidke, D.; Lemmon, M. A.
10.1101/2023.04.10.536273 — biophysics — Posted on 2023-04-10
2817 A novel and highly specific Forssman antigen-binding protein from sheep polyomavirus
Rustmeier, N. H.; Silva, L. M.; Di Maio, A.; Müller, J. C.; Herrmann, A.; Feizi, T.; Liu, Y.; Stehle, T.
10.1101/2023.04.10.536218 — biochemistry — Posted on 2023-04-10
2820 Rewiring of RNA methylation by the oncometabolite fumarate in renal cell carcinoma
Fitzsimmons, C. M.; Mandler, M. D.; Lunger, J. C.; Chan, D.; Maligireddy, S. S.; Schmiechen, A. C.; Gamage, S. T.; Link, C.; Jenkins, L. M.; Crooks, D. R.; Meier, J. L.; Linehan, W. M.; Batista, P. J.
10.1101/2023.04.10.536262 — molecular biology — Posted on 2023-04-10
2821 Probe capture enrichment sequencing of amoA genes discloses diverse ammonia-oxidizing archaeal and bacterial populations
Hiraoka, S.; Ijichi, M.; Takeshima, H.; Kumagai, Y.; Yang, C.-C.; Makabe-Kobayashi, Y.; Fukuda, H.; Yoshizawa, S.; Iwasaki, W.; Kogure, K.; Shiozaki, T.
10.1101/2023.04.10.536224 — microbiology — Posted on 2023-04-10
2822 Impact of Zinc Pre-exposure on de novo Antibiotic Resistance Development
Suprenant, M. P.; Ching, C.; Sutradhar, I.; Gross, N.; Anderson, J. E.; El Sherif, N.; Zaman, M. H.
10.1101/2023.04.10.536219 — microbiology — Posted on 2023-04-10
2825 The soil-borne white root rot pathogen Rosellinia necatrix expresses antimicrobial proteins during host colonization
Chavarro, E.; Snelders, N.; Torres, D.; Kraege, A.; Lopez-Moral, A.; Petti, G.; Punt, W.; Wieneke, J.; Garcia-Velasco, R.; Lopez-Herrera, C.; Seidl, M. F.; Thomma, B.
10.1101/2023.04.10.536216 — plant biology — Posted on 2023-04-10
2827 Direct monitoring of the thermodynamics and kinetics of DNA and RNA dinucleotide dehybridization from gaps and overhangs
Ashwood, B.; Jones, M. S.; Radakovic, A.; Khanna, S.; Lee, Y.; Sachleben, J. R.; Szostak, J. W.; Ferguson, A. L.; Tokmakoff, A.
10.1101/2023.04.10.536266 — biophysics — Posted on 2023-04-10
2828 Ionic polyphosphorylation of histidine repeat proteins by inorganic polyphosphate
Neville, N.; Lehotsky, K.; Yang, Z.; Klupt, K. A.; Denoncourt, A.; Downey, M.; Jia, Z.
10.1101/2023.04.10.536149 — biochemistry — Posted on 2023-04-10
2830 Single Cell Transcriptomics-informed Induced Pluripotent Stem Cells Differentiation to Tenogenic Lineage
Papalamprou, A.; Yu, V.; Jiang, W.; Sheyn, J.; Stefanovic, T.; Chen, A.; Castaneda, C.; Chavez, M.; Sheyn, D.
10.1101/2023.04.10.536240 — developmental biology — Posted on 2023-04-10
2832 Clostridium butyricum and Clostridium tyrobutyricum: angle or devil for Necrotizing enterocolitis?
Wei, Z. H.; Tao, R.; Zong, G. F.; Pan, Y. H.; Li, H. X.; Chen, P.; Deng, R.; Chen, W.; Wang, A.; Xia, S. S.; Tang, W. B.; Lu, Y.
10.1101/2023.04.10.536220 — microbiology — Posted on 2023-04-10
2833 Methylome-dependent transformation of emm1 group A streptococci
Alves, J.; Rand, J. D.; Johnston, A. B.; Bowen, C.; Lynskey, N. N.
10.1101/2023.04.10.536284 — microbiology — Posted on 2023-04-10
2834 Nutrient Limitation Sensitizes Pseudomonas aeruginosa to Vancomycin
Chan, D. C. K.; Dykema, K.; Fatima, M.; Harvey, H.; Qaderi, I.; Burrows, L. L.
10.1101/2023.04.10.536232 — microbiology — Posted on 2023-04-10
2837 Geochemical constraints on bacteriophage infectivity in terrestrial environments
Carlson, H. K.; Piya, D.; Moore, M. L.; Magar, R. T.; Elisabeth, N. H.; Deutschbauer, A. M.; Arkin, A. P.; Mutalik, V. K.
10.1101/2023.04.10.536276 — microbiology — Posted on 2023-04-10
2838 How individual P. aeruginosa cells with diverse stator distributions collectively form a heterogeneous macroscopic swarming population
de Anda, J.; Kuchma, S.; Webster, S. S.; Boromand, A.; Lewis, K. A.; Lee, C.; Contreras, M.; Medeiros Pereira, V. F.; Hogan, D. A.; O'Hern, C.; O'Toole, G. A.; Wong, G. C. L.
10.1101/2023.04.10.536285 — microbiology — Posted on 2023-04-10
2840 Quantitative MHC class-I/-II gene expression levels in CDK12 mutated prostate cancer reveal intratumorally T cell adaptive immune response in tumors
Lautert-Dutra, W.; Melo, C. M.; Chavez, L. P.; Crozier, C.; Saggioro, F. P.; dos Reis, R. B.; Bayani, J.; Bonatto, S.; Squire, J. A.
10.1101/2022.04.16.487364 — cancer biology — Posted on 2023-04-10
2843 Egg size variation and breeding phenology in a long-lived sequentially polygamous shorebird
Eberhart-Hertel, L. J.; Falcao Rodrigues, L.; Krietsch, J.; Eberhart-Hertel, A. G.; Cruz-Lopez, M.; Vazquez-Rojas, K. A.; Gonzalez-Medina, E.; Schroeder, J.; Küpper, C.
10.1101/2020.08.07.240150 — evolutionary biology — Posted on 2023-04-10
2847 High-throughput phenogenotyping of Mycobacteria tuberculosis clinical strains reveals bacterial determinants of treatment outcomes
Stanley, S.; Spaulding, C. N.; Liu, Q.; Chase, M. R.; Ha, D. T. M.; Thai, P. V. K.; Lan, N. H.; Thu, D. D. A.; Quang, N. L.; Brown, J.; Hicks, N. D.; Wang, X.; Marin, M.; Howard, N. C.; Vickers, A. J.; Karpinski, W. M.; Chao, M. C.; Farhat, M. R.; Caws, M.; Dunstan, S. J.; Thuong, N. T. T.; Fortune, S. M.
10.1101/2023.04.09.536166 — microbiology — Posted on 2023-04-10
2849 High-fidelity reproduction of visual signals by electrical stimulation in the central primate retina
Gogliettino, A. R.; Madugula, S. S.; Grosberg, L. E.; Vilkhu, R. S.; Brown, J.; Nguyen, H.; Kling, A.; Hottowy, P.; Dabrowski, W.; Sher, A.; Litke, A. M.; Chichilnisky, E. J.
10.1101/2022.05.24.493162 — neuroscience — Posted on 2023-04-10
2851 Trafficking dynamics of VEGFR1, VEGFR2, and NRP1 in human endothelial cells
Sarabipour, S.; Kinghorn, K.; Quigley, K. M.; Kovacs-Kasa, A.; Annex, B. H.; Bautch, V. L.; Mac Gabhann, F.
10.1101/2022.09.30.510412 — systems biology — Posted on 2023-04-10
2853 Myelodysplastic syndromes disable human CD271+VCAM1+CD146+ niches supporting normal hematopoietic stem/progenitor cells
kawano, Y.; Kawano, H.; Ghoneim, D.; Fountaine, T. J.; Byun, D. K.; LaMere, M. W.; Mendler, J. H.; Ho, T.; Salama, N. A.; Myers, J. R.; Hussein, S. E.; Frisch, B. J.; Ashton, J. M.; Azadniv, M.; Liesveld, J. L.; Kfoury, Y.; Scadden, D. T.; Becker, M. W.; Calvi, L. M.
10.1101/2023.04.09.536176 — cancer biology — Posted on 2023-04-10
2855 Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder-Robinson syndrome: mechanism of action and therapeutic potential
Stewart, T. R. M.; Foley, J. R.; Holbert, C. E.; Khomutov, M. A.; Rastkari, N.; Tao, X.; Khomutov, A. R.; Zhai, R. G.; Casero, R. A.
10.1101/2023.03.30.534977 — biochemistry — Posted on 2023-04-10
2857 NULISA: a novel proteomic liquid biopsy platform with attomolar sensitivity and high multiplexing
Feng, W.; Beer, J.; Hao, Q.; Ariyapala, I. S.; Sahajan, A.; Komarov, A.; Cha, K.; Moua, M.; Qiu, X.; Xu, X.; Iyengar, S.; Yoshimura, T.; Nagaraj, R.; Wang, L.; Yu, M.; Engel, K.; Zhen, L.; Xue, W.; Lee, C.-j.; Park, C. H.; Peng, C.; Zhang, K.; Grzybowski, A.; Hahm, J.; Schmidt, S. V.; Odainic, A.; Spitzer, J.; Bonn COVIMMUNE Consortium, ; Buddika, K.; Kuo, D.; Fang, L.; Zhang, B.; Chen, S.; Latz, E.; Yin, Y.; Luo, Y.; Ma, X.-J.
10.1101/2023.04.09.536130 — genomics — Posted on 2023-04-10
2859 The time integral of BMP signaling determines fate in a stem cell model for early human development
Teague, S.; Primavera, G.; Chen, B.; Freeburne, E.; Khan, H. A.; Jo, K.; Johnson, C. N.; Heemskerk, I.
10.1101/2023.04.10.536068 — developmental biology — Posted on 2023-04-10
2862 Protective effect of pre-existing natural immunity in a nonhuman primate reinfection model of congenital cytomegalovirus infection
Mostrom, M. J.; Yu, S.; Tran, D.; Saccoccio, F.; Versoza, C. J.; Malouli, D. J.; Mirza, A.; Valencia, S.; Gilbert, M.; Blair, R. V.; Hansen, S. G.; Barry, P. A.; Fruh, K.; Jensen, J. D.; Pfeifer, S. P.; Kowalik, T. F.; Permar, S. R.; Kaur, A.
10.1101/2023.04.10.536057 — immunology — Posted on 2023-04-10
2863 Corticotropin Releasing Factor in the Bed Nucleus of the Stria Terminalis modulates the behavioral consequences of unpredictable threat
Hon, O. J.; Flanigan, M.; Roland, A.; Caira, C.; Sides, T.; D'Ambrosio, S.; Lee, S.; Simpson, Y.; Buccini, M.; Machinski, S.; Yu, W.; Boyt, K.; Kash, T.
10.1101/2023.04.10.535848 — neuroscience — Posted on 2023-04-10
2866 Antibodies that neutralize all current SARS-CoV-2 variants of concern by conformational locking
Liu, L.; Casner, R. G.; Guo, Y.; Wang, Q.; Iketani, S.; Chan, J. F.-W.; Yu, J.; Dadonaite, B.; Nair, M. S.; Mohri, H.; Reddem, E. R.; Yuan, S.; Poon, V. K.-M.; Chan, C. C.-S.; Yuen, K.-Y.; Sheng, Z.; Huang, Y.; Bloom, J. D.; Shapiro, L.; Ho, D. D.
10.1101/2023.04.08.536123 — microbiology — Posted on 2023-04-10
2867 Effect of temperature on mosquito olfaction
Lahondere, C.; Vinauger, C.; Liaw, J. E.; Tobin, K. K. S.; Joiner, J. M.; Riffell, J. A.
10.1101/2023.04.10.535894 — neuroscience — Posted on 2023-04-10
2868 SARS-CoV-2's evolutionary capacity is mostly driven by host antiviral molecules
Lamb, K. D.; Luka, M. M.; Saathoff, M.; Orton, R.; Phan, M.; Cotten, M.; Yuan, K.; Robertson, D. L.
10.1101/2023.04.07.536037 — genomics — Posted on 2023-04-10
2870 Fine-scale sampling uncovers the complexity of migrations in 5th-6th century Pannonia
Vyas, D. N.; Koncz, I.; Modi, A.; Mende, B. G.; Tian, Y.; Francalacci, P.; Lari, M.; Vai, S.; Straub, P.; Gallina, Z.; Szeniczey, T.; Hajdu, T.; Radzeviciute, R.; Hofmanova, Z.; Evinger, S.; Bernert, Z.; Pohl, W.; Caramelli, D.; Vida, T.; Geary, P. J.; Veeramah, K. R.
10.1101/2022.09.26.509582 — genetics — Posted on 2023-04-10
2873 Comprehensive insight into the alterations in the gut microbiome and the intestinal barrier as a consequence of iron deficiency anaemia
Soriano-Lerma, A.; Garcia-Burgos, M.; Barton, W.; Munoz Alferez, M. J.; Crespo-Perez, J. V.; Soriano, M.; Lopez-Aliaga, I.; Cotter, P. D.; Garcia-Salcedo, J. A.
10.1101/2023.04.10.536197 — pathology — Posted on 2023-04-10
2875 PMIpred: A physics-informed web server for quantitative Protein-Membrane Interaction prediction
van Hilten, N.; Verwei, N.; Methorst, J.; Nase, C.; Bernatavicius, A.; Risselada, H. J.
10.1101/2023.04.10.536211 — biophysics — Posted on 2023-04-10
2876 ReCom: A semi-supervised approach to ultra-tolerant database search for improved identification of modified peptides
Laguillo-Gomez, A.; Calvo, E.; Martin-Cofreces, N.; Lozano-Prieto, M.; Sanchez-Madrid, F.; Vazquez, J.
10.1101/2023.04.10.535358 — bioinformatics — Posted on 2023-04-10
2879 Glycopolymer-conjugated antigens as an inverse vaccine platform prevent anaphylaxis in a pre-clinical model of food allergy
Cao, S.; Maulloo, C. D.; Raczy, M. M.; Sabados, M.; Slezak, A. J.; Nguyen, M.; Solanki, A.; Wallace, R. P.; Shim, H.-N.; Wilson, D. S.; Hubbell, J. A.
10.1101/2023.03.23.534004 — bioengineering — Posted on 2023-04-10
2882 The exosome degrades chromatin-associated RNAs genome-wide and maintains chromatin homeostasis
Planells, J.; Jordan Pla, A.; Jain, S.; Guadalupe, J. J.; Proux-Wera, E.; von Euler, A.; Pelechano, V.; Visa, N.
10.1101/2023.04.10.536209 — genomics — Posted on 2023-04-10
2883 Universal method for generating knockout mice in multiple genetic backgrounds using zygote electroporation
Tamari, T.; Ikeda, Y.; Morimoto, K.; Kobayashi, K.; Mizuno-Iijima, S.; Ayabe, S.; Kuno, A.; Mizuno, S.; Yoshiki, A.
10.1101/2023.04.10.536207 — genetics — Posted on 2023-04-10
2887 Sexually dimorphic dynamics of the microtubule network in medaka (Oryzias latipes) germ cells
Kikuchi, M.; Yoshimoto, M.; Nishimura, T.; Ishikawa, T.; Kanda, Y.; Mori, K.; Tanaka, M.
10.1101/2023.04.09.536194 — developmental biology — Posted on 2023-04-10
2888 3D environment modulates persistent lamin distribution and the biomechanical signature of the nucleus.
Gonzalez-Novo, R.; Zamora Carreras, H.; De Lope-Planelles, A.; Lopez-Menendez, H.; Roda-Navarro, p.; Monroy, F.; Wang, L.; Toseland, C. P.; Redondo-Munoz, J.
10.1101/2023.04.10.536202 — cell biology — Posted on 2023-04-10
2890 High-throughput phenogenotyping of Mycobacteria tuberculosis clinical strains reveals bacterial determinants of treatment outcomes
Stanley, S.; Spaulding, C. N.; Liu, Q.; Chase, M. R.; Ha, D. T. M.; Thai, P. V. K.; Lan, N. H.; Thu, D. D. A.; Quang, N. L.; Brown, J.; Hicks, N. D.; Wang, X.; Marin, M.; Howard, N. C.; Vickers, A. J.; Karpinski, W. M.; Chao, M. C.; Farhat, M. R.; Caws, M.; Dunstan, S. J.; Thuong, N. T. T.; Fortune, S. M.
10.1101/2023.04.09.536166 — microbiology — Posted on 2023-04-10
2894 A neural mass model for the EEG in ischemia
Kalia, M.; Ligtenstein, S. L. B.; Meijer, H. G. E.; van Putten, M. J. A. M.
10.1101/2023.04.07.535995 — neuroscience — Posted on 2023-04-10
2895 Glial Draper signaling triggers cross-neuron plasticity in bystander neurons after neuronal cell death
Wang, Y.; Zhang, R.; Huang, S.; Valverde, P. T.-T.; Lobb-Rabe, M.; Ashley, J.; Venkatasubramanian, L.; Carrillo, R. A.
10.1101/2023.04.09.536190 — neuroscience — Posted on 2023-04-10
2896 Adolescent morphine exposure impairs cognitive flexibility in female but not male mice.
Wakhlu, A.; Engelhardt, A.; Andersion, E.; Grafelman, E.; Ouimet, A.; Hearing, M.
10.1101/2023.04.09.536177 — neuroscience — Posted on 2023-04-10
2897 Cocaine Seeking And Taking Are Oppositely Regulated By Dopamine
Burgeno, L. M.; Farero, R. D.; Murray, N. L.; Panayi, M. C.; Steger, J. S.; Evans, S. B.; Sandberg, S. G.; Willuhn, I.; Zweifel, L. S.; Phillips, P. E. M.
10.1101/2023.04.09.536189 — neuroscience — Posted on 2023-04-10
2900 Clathrin Light Chains are essential in negative regulation of cell death and immunity in Arabidopsis through interacting with autophagy pathway
Lan, H.-J.; Ran, J.; Zhang, L.; Wu, N.-N.; Wang, W.-X.; Ni, M.; Cheng, N.; Nakata, P. A.; Pan, J.; Whitham, S.; Liu, J.
10.1101/2023.04.09.535952 — plant biology — Posted on 2023-04-10
2902 A critical role for PLCG1 in RAS activation by BCR-ABL1 and FLT3-ITD
Szeto, M. Y.; Mase, A.; Kulhanek, K.; Banerjee, S.; Rubio, I.; Roose, J.; Shah, N. P.
10.1101/2023.04.07.536070 — cancer biology — Posted on 2023-04-10
2903 Lattice-Boltzmann Modelling for Inertial Particle Microfluidics Applications -A Tutorial Review
Owen, B.; Kechagidis, K.; Bazaz, S. R.; Enjalbert, R.; Essman, E.; Malorie, C.; Mirghaderi, F.; Schaaf, C.; Thota, K.; Vernekar, R.; Zhou, Q.; Warkiani, M. E.; Stark, H.; Krueger, T.
10.1101/2023.04.10.536205 — biophysics — Posted on 2023-04-10
2904 GALBA: Genome Annotation with Miniprot and AUGUSTUS
Bruna, T.; Li, H.; Guhlin, J.; Honsel, D.; Herbold, S.; Stanke, M.; Nenasheva, N.; Ebel, M.; Gabriel, L.; Hoff, K. J.
10.1101/2023.04.10.536199 — bioinformatics — Posted on 2023-04-10
2905 HSP70 binds to specific non-coding RNA and regulates human RNA Polymerase III
Leone, S.; Srivastava, A.; Hummel, B.; Tittel, L.; Aprile-Garcia, F.; Herrero-Ruiz, A.; Rawat, P.; Willis, A. E.; Sawarkar, R.
10.1101/2023.04.10.536203 — biochemistry — Posted on 2023-04-10
2907 Activation of the P2RX7/IL-18 pathway in immune cells attenuates lung fibrosis
Janho dit Hreich, S.; Juhel, T.; Leroy, S.; Brau, F.; Hofman, V.; Hofman, P.; Vouret-Craviari, V.
10.1101/2022.12.15.520590 — immunology — Posted on 2023-04-10
2909 Estimating the cumulative impact and zone of influence of anthropogenic features on biodiversity
Niebuhr, B. B.; van Moorter, B.; Stien, A.; Tveraa, T.; Strand, O.; Langeland, K.; Sandström, P.; Alam, M.; Skarin, A.; Panzacchi, M.
10.1101/2022.06.14.495994 — ecology — Posted on 2023-04-10
2914 Lessons from relatives: C4 photosynthesis enhances CO2 assimilation during the low-light phase of fluctuations.
Arce Cubas, L.; Rodrigues Gabriel Sales, C.; Vath, R. L.; Bernardo, E. L.; Burnett, A. C.; Kromdijk, J.
10.1101/2023.04.03.535443 — plant biology — Posted on 2023-04-10
2915 A dopaminergic memory circuit controls acute valence
Mohammad, F.; Mai, Y.; Ho, J.; Zhang, X.; Ott, S.; Stewart, J. C.; Claridge-Chang, A.
10.1101/2022.11.23.517775 — animal behavior and cognition — Posted on 2023-04-10
2917 Astrocytic LRRK2 Controls Synaptic Connectivity through ERM Phosphorylation
Wang, S.; Sivadasan Bindu, D.; Tan, C. X.; Sakers, K.; Takano, T.; Rodriguez Salazar, M. P.; Dimond, K.; Soderling, S. H.; La Spada, A. R.; Eroglu, C.
10.1101/2023.04.09.536178 — neuroscience — Posted on 2023-04-10
2918 Lidocaine Induces Apoptosis in Head and Neck Squamous Cell Carcinoma Cells Through Activation of Bitter Taste Receptor T2R14
Miller, Z. A.; Mueller, A.; Jolivert, J. F.; Ma, R. Z.; Muthuswami, S.; Park, A.; McMahon, D. B.; Carey, R. M.; Lee, R. J.
10.1101/2022.11.22.517413 — cancer biology — Posted on 2023-04-09
2924 A modular metagenomics analysis system for integrated multi-step data exploration
Mak, L.; Tierney, B.; Ronkowski, C.; Toomey, M.; Martinez, J. S. A.; Zimmerman, S.; Fu, C.; Kopbayeva, M.; Noyvert, A.; Farthing, B.; Tang, S.; Mason, C.; Hajirasouliha, I.
10.1101/2023.04.09.536171 — bioinformatics — Posted on 2023-04-09
2925 Discovery and Engineering of the L-Threonine Aldolase from Neptunomonas Marine for Efficient Synthesis of β-Hydroxy-α-Amino Acids via C-C Formation
He, Y.; Li, S.; Wang, J.; Yang, X.; Zhu, J.; Zhang, Q.; Cui, L.; Tan, Z.; Zhang, Y.; Yan, W.; Tang, L.; Da, L.-t.; Feng, Y.
10.1101/2023.04.09.536162 — biochemistry — Posted on 2023-04-09
2926 Evolutionary trajectories of secondary replicons in multipartite genomes
Dranenko, N. O.; Rodina, A. D.; Demenchuk, Y. V.; Gelfand, M. S.; Bochkareva, O. O.
10.1101/2023.04.09.536151 — genomics — Posted on 2023-04-09
2929 A PCR-RFLP method for the detection of CRISPR-induced indels
Angelopoulou, L.; Stylianopoulou, E.; Tegopoulos, K.; Farmakioti, I.; Grigoriou, M. E.; Skavdis, G.
10.1101/2023.04.09.535589 — molecular biology — Posted on 2023-04-09
2930 Boosting BDNF in muscle rescues impaired in vivo axonal transport in a mouse model of DI-CMTC peripheral neuropathy
Rhymes, E. R.; Simkin, R. L.; Surana, S. N.; Tong, Y.; Villarroel-Campos, D.; Yang, X.-L.; Schiavo, G.; Sleigh, J. N.
10.1101/2023.04.09.536152 — neuroscience — Posted on 2023-04-09
2932 Simultaneous representation of multiple time horizons by entorhinal grid cells and CA1 place cells
Chaudhuri-Vayalambrone, P.; Rule, M. E.; Bauza, M.; Krstulovic, M.; Kerekes, P.; Burton, S.; O'Leary, T.; Krupic, J.
10.1101/2023.04.09.536160 — neuroscience — Posted on 2023-04-09
2933 Do perineuronal nets stabilize the engram of a synaptic circuit?
Lev-Ram, V.; Palida, S.; Deerinck, T. J.; Bushong, E. A.; Toyoma, B. H.; Perez, A.; McClatchy, D. B.; Prichard, D. R.; Savas, J. N.; Ellisman, M. H.; Yates, J. R.; Tsien, R. Y.
10.1101/2023.04.09.536164 — neuroscience — Posted on 2023-04-09
2936 Myelodysplastic syndromes disable human CD271+VCAM1+CD146+ niches supporting normal hematopoietic stem/progenitor cells
kawano, Y.; Kawano, H.; Ghoneim, D.; Fountaine, T. J.; Byun, D. K.; LaMere, M. W.; Mendler, J. H.; Ho, T.; Salama, N. A.; Myers, J. R.; Hussein, S. E.; Frisch, B. J.; Ashton, J. M.; Azadniv, M.; Liesveld, J. L.; Kfoury, Y.; Scadden, D. T.; Becker, M. W.; Calvi, L. M.
10.1101/2023.04.09.536176 — cancer biology — Posted on 2023-04-09
2938 Photoswitchable Molecular Glues Enable Optical Control of Transcription Factor Degradation
Arp, C. J.; Reynders, M.; Sreekanth, V.; Kokkonda, P.; Pagano, M.; Choudhary, A.; Trauner, D.
10.1101/2023.04.09.536172 — biochemistry — Posted on 2023-04-09
2939 mps1 and mad mutations reduce Cryptococcus neoformans titan cell viability
Aktar, K.; Davies, T.; Leontiou, I.; Clark, I.; Spanos, C.; Wallace, E.; Tuck, L.; Jeyaprakash, A. A.; Hardwick, K.
10.1101/2023.04.09.536157 — cell biology — Posted on 2023-04-09
2940 Caenorhabditis elegans models for striated muscle disorders caused by missense variants of human LMNA
Gregory, E. F.; Kalra, S.; Brock, T.; Bonne, G.; Luxton, G. G.; Hopkins, C.; Starr, D. A.
10.1101/2023.04.09.536174 — cell biology — Posted on 2023-04-09
2942 Diverse Gut Pathogens Exploit the Host Engulfment Pathway via a Conserved Mechanism
Anandachar, M. S.; Agyekum, B.; Sinha, S.; Roy, S.; Ibeawuchi, S.-R.; Gementera, H.; Amamoto, A.; Katkar, G. D.; Ghosh, P.
10.1101/2023.04.09.536168 — immunology — Posted on 2023-04-09
2943 Tissue-specific vulnerability to apoptosis in Machado-Joseph disease
Ferreira, A. F.; Raposo, M.; Shaw, E. D.; Ashraf, N. S.; Medeiros, F.; Brilhante, M. d. F.; Perkins, M.; Vasconcelos, J.; Kay, T.; Costa, M. d. C.; Lima, M.
10.1101/2023.04.09.536069 — neuroscience — Posted on 2023-04-09
2944 Pervasive Transcriptome Interactions of Protein-Targeted Drugs
Fang, L.; Velema, W. A.; Lee, Y.; Xiao, L.; Mohsen, M. G.; Kietrys, A. M.; Kool, E. T.
10.1101/2022.07.18.500496 — pharmacology and toxicology — Posted on 2023-04-09
2949 Dynamic oxygen-enhanced MRI of the lung at 3 T: feasibility, repeatability and reproducibility
Kim, M.; Naish, J. H.; Needleman, S. H.; Tibiletti, M.; Taylor, Y.; O'Connor, J. P. B.; Parker, G. J. M.
10.1101/2023.04.09.536144 — biophysics — Posted on 2023-04-09
2950 Dose-response relationship for the resistance of human insulin to degradation by insulin-degrading enzyme
Okumura, M.; Kuramochi, T.; Lin, Y.; Furukawa, R.; Mizutani, K.; Yokoyama, T.; Kim, M.; Lim, M. H.; Yi, H.-S.; Arai, K.; Yamaguchi, H.; Hojo, H.; Iwaoka, M.; Tanaka, Y.; Park, S.-Y.; Inaba, K.; Kanemura, S.; Lee, Y.-H.
10.1101/2023.04.08.536135 — biochemistry — Posted on 2023-04-09
2951 Distinct roles of PV and Sst interneurons in visually-induced gamma oscillations
Onorato, I.; Tzanou, A.; Schneider, M.; Uran, C.; Broggini, A. C.; Vinck, M.
10.1101/2023.04.08.535291 — neuroscience — Posted on 2023-04-09
2955 Darapladib, an inhibitor of Lp-PLA2, sensitizes cancer cells to ferroptosis by remodeling lipid metabolism
Oh, M.; Jang, S. Y.; Lee, J.-Y.; Kim, J. W.; Jung, Y.; Seo, J.; Han, T.-S.; Jang, E.; Son, H. Y.; Kim, D.; Kim, M. W.; Song, K.-H.; Oh, K.-J.; Kim, W. K.; Bae, K.-H.; Huh, Y.-M.; Han, B.-S.; Lee, S. C.; Hwang, G.-S.; Lee, E.-W.
10.1101/2023.04.08.536136 — cancer biology — Posted on 2023-04-09
2956 Reinstating targeted protein degradation with DCAF1 PROTACs in CRBN PROTAC resistant settings
Schroeder, M.; Renatus, M.; Liang, X.; Meili, F.; Ferrand, S.; Gauter, F.; Li, X.; Sigoillot, F.; Gleim, S.; Stachyra, M.-T.; Thomas, J.; Schirle, M.; Zoller, T.; Begue, D.; Lefeuvre, P.; Chung, B.; Ma, R.; Carbonneau, S.; Pinch, B.; Schmiedeberg, N.; Imbach, P.; Hofmann, A.; Rey, R.; Gorses, D.; Calkins, K.; Bauer-Probst, B.; Maschlej, M.; Niederst, M.; Maher, R.; Henault, M.; Alford, J.; Ahrne, E.; Hollingworth, G.; Thomae, N. H.; Vulpetti, A.; Radimerski, T.; Holzer, P.; Thoma, C. R.
10.1101/2023.04.09.536153 — biochemistry — Posted on 2023-04-09
2957 Latent taste diversity revealed by a vertebrate-wide catalogue of T1R receptors
Nishihara, H.; Toda, Y.; Kuramoto, T.; Kamohara, K.; Goto, A.; Hoshino, K.; Okada, S.; Kuraku, S.; Okabe, M.; Ishimaru, Y.
10.1101/2023.04.08.532961 — evolutionary biology — Posted on 2023-04-09
2958 Spatial and Temporal Origin of The Third SARS-Cov-2 Outbreak in Taiwan
Tai, J.-H.; Low, Y. K.; Wang, S. C.-L.; Lin, H.-F.; Wang, T.-Y.; Lin, Y.-Y.; Foster, C.; van Hal, S. J.; Lai, Y.-Y.; Yeh, S.-H.; Chang, S.-Y.; Chen, P.-J.; Chaw, S.-M.
10.1101/2022.07.04.498645 — evolutionary biology — Posted on 2023-04-09
2961 Virological characteristics of the SARS-CoV-2 Omicron XBB.1.16 variant
Yamasoba, D.; Uriu, K.; Plianchaisuk, A.; Kosugi, Y.; Pan, L.; Zahradnik, J.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Ito, J.; Sato, K.
10.1101/2023.04.06.535883 — microbiology — Posted on 2023-04-09
2962 Primary Somatosensory Cortex Bidirectionally Modulates Sensory Gain and Nociceptive Behavior in a Layer-Specific Manner
Ziegler, K.; Folkard, R.; Gonzalez, A.; Burghardt, J.; Antharvedi-Goda, S.; Martin-Cortecero, J.; Isaias-Camacho, E.; Kaushalya, S.; Tan, L. L.; Kuner, T.; Acuna, C.; Kuner, R.; Mease, R.; Groh, A.
10.1101/2022.08.02.502350 — neuroscience — Posted on 2023-04-09
2971 Tree-based QTL mapping with expected local geneticrelatedness matrices
Link, V.; Schraiber, J. G.; Fan, C.; Dinh, B.; Mancuso, N.; Chiang, C. W. K.; Edge, M. D.
10.1101/2023.04.07.536093 — genetics — Posted on 2023-04-08
2972 GATA1 knockout in human pluripotent stem cells generates enhanced neutrophils to investigate extracellular trap formation
Harper, T. C.; Oberlick, E. M.; Smith, T. J.; Nunes, D. E.; Bray, M. A.; Park, S.; Driscoll, C. D.; Mowbray, S. F.; Antczak, C.
10.1101/2023.02.08.526339 — immunology — Posted on 2023-04-08
2974 A statistical framework for quantifying the nuclear export rate of influenza viral mRNAs.
Miura, M.; Kiuchi, N.; Lau, S.-Y.; Mok, B. W.-Y.; Ushirogawa, H.; Naito, T.; Chen, H.; Saito, M.
10.1101/2023.04.07.536075 — systems biology — Posted on 2023-04-08
2981 Comparative single cell epigenomic analysis of gene regulatory programs in the rodent and primate neocortex
Zemke, N. R.; Armand, E. J.; Wang, W.; Lee, S.; Zhou, J.; Li, Y. E.; Liu, H.; Tian, W.; Nery, J. R.; Castanon, R. G.; Bartlett, A.; Osteen, J. K.; Li, D.; Zhuo, X.; Xu, V.; Miller, M.; Krienen, F. M.; Zhang, Q.; Taskin, N.; Ting, J.; Feng, G.; McCarroll, S. A.; Callaway, E. M.; Wang, T.; Behrens, M.; Lein, E. S.; Ecker, J. R.; Ren, B.
10.1101/2023.04.08.536119 — genomics — Posted on 2023-04-08
2983 Analysis of the Combined Effect of rs699 and rs5051 on Angiotensinogen Expression and Hypertension
Powell, N. R.; Shugg, T.; Leighty, J.; Martin, M.; Kreutz, R. P.; Eadon, M. T.; Lai, D.; Lu, T.; Skaar, T. C.
10.1101/2023.04.07.536073 — genetics — Posted on 2023-04-08
2991 Dose-dependent progression of multiple low dose streptozotocin-induced diabetes in mice
Bauer, B. M.; Bhattacharya, S.; Bloom-Saldana, E.; Irimia, J. M.; Fueger, P. T.
10.1101/2023.04.08.536122 — physiology — Posted on 2023-04-08
2994 Pan-cancer analysis of the ion permeome reveals functional regulators of glioblastoma aggression
Bahcheli, A. T.; Min, H.-K.; Bayati, M.; Dong, W.; Fortuna, A.; Zhao, H.; Dzneladze, I.; Chan, J.; Chen, X.; Guevara-Hoyer, K.; Dirks, P. B.; Huang, X.; Reimand, J.
10.1101/2023.04.07.536030 — cancer biology — Posted on 2023-04-08
2995 Inhibition of serotonin biosynthesis in neuroendocrine neoplasm suppressestumor growth in vivo
Tow, D. H.; Tran, C. G.; Borbon, L. C.; Ridder, M.; Li, G.; Kaemmer, C. A.; Abusada, E.; Mahalingam, A. H.; Sadanandam, A.; Chandrasekharan, C.; Dillon, J.; Spitz, D. R.; Quelle, D. E.; Chan, C. H. F.; Bellizzi, A. M.; Howe, J. R.; Ear, P. H.
10.1101/2023.04.07.536013 — cancer biology — Posted on 2023-04-08
3002 Independently evolved pollution resistance in four killifish populations is largely explained by few variants of large effect
Miller, J. T.; Clark, B. W.; Reid, N. M.; Karchner, S. I.; Roach, J. L.; Hahn, M. E.; Nacci, D.; Whitehead, A.
10.1101/2023.04.07.536079 — evolutionary biology — Posted on 2023-04-08
3003 DEVELOPMENTAL ULTRASTRUTCTURE MICROSCOPY IN DRUG DISCOVERY FROM DIOSCOREA SPECIES
Odimegwu, J. I.; Sangwan,, N. S.; Chanotiya, C. S.; Ogbonnia, S. O.; Odukoya, O. A.
10.1101/2023.04.07.535999 — developmental biology — Posted on 2023-04-08
3005 Predictive links between petal color and pigment quantities in natural Penstemon hybrids
Stevens, J. T. E.; Wheeler, L. C.; Williams, N. H.; Norton, A. M.; Wessinger, C. A.
10.1101/2023.04.06.535869 — systems biology — Posted on 2023-04-08
3008 Targeting MCL1-driven anti-apoptotic pathways to overcome hypomethylating agent resistance in RAS-mutated chronic myelomonocytic leukemia
Montalban-Bravo, G.; Ma, F.; Thongon, N.; Yang, H.; Ganan-Gomez, I.; Rodriguez-Sevilla, J. J.; Adema, V.; Wildeman, B.; Lockyer, P. P.; Kim, Y. J.; Tanaka, T.; Darbaniyan, F.; Pancholy, S.; Zhang, G.; Al-Atrash, G.; Dwyer, K.; Takahashi, K.; Garcia-Manero, G.; Kantarjian, H.; Colla, S.
10.1101/2023.04.07.535928 — cancer biology — Posted on 2023-04-08
3012 Archaeal self-activating GPN-loop GTPases involve a lock-switch-rock mechanism for GTP hydrolysis
Korf, L.; Ye, X.; Vogt, M. S.; Steinchen, W.; Watad, M.; Tourte, M.; Sivabalasarma, S.; Albers, S.-V.; Essen, L.-O.
10.1101/2023.04.08.536109 — biochemistry — Posted on 2023-04-08
3013 The origin of a mountain biota: hyper-aridity shaped reptile diversity in an Arabian biodiversity hotspot
Burriel-Carranza, B.; Tejero-Cicuendez, H.; Carne, A.; Riano, G.; Talavera, A.; Al Saadi, S.; Els, J.; Smid, J.; Tamar, K.; Tarroso, P.; Carranza, S.
10.1101/2023.04.07.536010 — evolutionary biology — Posted on 2023-04-08
3014 Shifts in the coral microbiome in response to in situ experimental deoxygenation
Howard, R. D.; Schul, M.; Rodriguez Bravo, L. M.; Altieri, A.; Meyer, J. L.
10.1101/2023.04.06.535971 — ecology — Posted on 2023-04-08
3016 Experimental Factors Influence Diversity Metrics of the Gut Microbiome in Laboratory Mice
R Muralitharan, R.; Nakai, M.; Snelson, M.; Zheng, T.; Dinakis, E.; Xie, L.; Jama, H.; Paterson, M.; Shihata, W.; Wassef, F.; Vinh, A.; Drummond, G. R.; Kaye, D. M.; Mackay, C. R.; Marques, F. Z.
10.1101/2023.04.08.536089 — microbiology — Posted on 2023-04-08
3018 The Chromatin Landscape of Pathogenic Transcriptional Cell States in Rheumatoid Arthritis
Weinand, K.; Sakaue, S.; Nathan, A.; Jonsson, A. H.; Zhang, F.; Watts, G. F. M.; Zhu, Z.; Accelerating Medicines Partnership Program: RA and SLE Network, ; Rao, D. A.; Anolik, J. H.; Brenner, M. B.; Donlin, L. T.; Wei, K.; Raychaudhuri, S.
10.1101/2023.04.07.536026 — immunology — Posted on 2023-04-08
3023 Δ246p53 is a new p53 isoform that responds to DNA damage and regulates tumour growth
Parkar, S. N.; Lopez-Iniesta, M. J.; Ramalho, A. C.; Kimura, K.; Zhao, J.; da Silva Rita, F.; Romao, L.; Candeias, M. M.
10.1101/2023.04.07.536059 — cancer biology — Posted on 2023-04-08
3024 A Weighted Two-stage Sequence Alignment Framework to Identify DNA Motifs from ChIP-exo Data
Li, Y.; Wang, Y.; Wang, C.; Fennel, A.; Ma, A.; Jiang, J.; Liu, Z.; Ma, Q.; Liu, B.
10.1101/2023.04.06.535915 — bioinformatics — Posted on 2023-04-08
3027 Genetic variation in Loudetia simplex supports the presence of ancient grasslands in Madagascar
Tiley, G. P.; Crowl, A. A.; Almary, T. O.; Luke, W. R.; Solofondranohatra, C. L.; Besnard, G.; Lehmann, C. E.; Yoder, A. D.; Vorontsova, M. S.
10.1101/2023.04.07.536094 — evolutionary biology — Posted on 2023-04-08
3028 Systematic mapping of chemoreceptor specificities for Pseudomonas aeruginosa
Xu, W.; Cerna-Vargas, J. P.; Tajuelo, A.; Montoya, A. L.; Kivoloka, M.; Krink, N.; Monteagudo-Cascales, E.; Matilla, M. A.; Krell, T.; Sourjik, V.
10.1101/2023.04.04.535651 — microbiology — Posted on 2023-04-08
3031 Exploiting rodent cell blocks for intrinsic resistance to HIV-1 gene expression in human T cells
Behrens, R. T.; Rajashekar, J. K.; Bruce, J.; Evans, E. L.; Hansen, A. M.; Salazar-Quiroz, N.; Simons, L. M.; Ahlquist, P.; Hultquist, J. F.; Kumar, P.; Sherer, N. M.
10.1101/2023.04.08.536105 — microbiology — Posted on 2023-04-08
3034 Multiple brain activation patterns for the same task
Nakuci, J.; Yeon, J.; Kim, J.-H.; Kim, S.-P.; Rahnev, D.
10.1101/2023.04.08.536107 — neuroscience — Posted on 2023-04-08
3037 Broad functional profiling of fission yeast proteins using phenomics and machine learning
Rodriguez-Lopez, M.; Bordin, N.; Lees, J.; Scholes, H.; Hassan, S.; Saintain, Q.; Kamrad, S.; Orengo, C.; Bähler, J.
10.1101/2023.04.05.535764 — genetics — Posted on 2023-04-08
3040 Rats emit aversive 44-kHz ultrasonic vocalizations during prolonged Pavlovian fear conditioning
Olszynski, K. H.; Polowy, R.; Wardak, A. D.; Laska, I. A.; Grymanowska, A. W.; Pulawski, W.; Gawrys, O.; Kolinski, M.; Filipkowski, R. K.
10.1101/2023.04.06.535936 — neuroscience — Posted on 2023-04-08
3041 Obstructive Sleep Apnea Improves with Non-invasive Hypoglossal Nerve Stimulation using Temporal Interference
MISSEY, F.; Ejneby, M. S.; Ngom, I.; Donahue, M. J.; Trajlinek, J.; ACERBO, E.; Botzanowski, B.; Cassara, A.; Neufeld, E.; Glowacki, E. D.; Shangold, L.; Hanes, W. M.; Williamson, A.
10.1101/2023.04.06.535917 — neuroscience — Posted on 2023-04-08
3042 A longitudinal resource for population neuroscience of school-age children and adolescents in China
Fan, X.-R.; Wang, Y.-S.; Chang, D.; Yang, N.; Rong, M.-J.; Zhang, Z.; He, Y.; Hou, X.; Zhou, Q.; Gong, Z.-Q.; Cao, L.-Z.; Dong, H.-M.; Nie, J.-J.; Chen, L.-Z.; Zhang, Q.; Zhang, J.-X.; Li, H.-J.; Bao, M.; Chen, A.; Chen, J.; Chen, X.; Ding, J.; Dong, X.; Du, Y.; Feng, C.; Feng, T.; Fu, X.; Ge, L.-K.; Hong, B.; Hu, X.; Huang, W.; Jiang, C.; Li, L.; Li, Q.; Li, S.; Liu, X.; Mo, F.; Qiu, J.; Su, X.-Q.; Wei, G.-X.; Wu, Y.; Xia, H.; Yan, C.-G.; Yan, Z.-X.; Yang, X.; Zhang, W.; Zhao, K.; Zhu, L.; Lifespan Brain Chart Consortium, ; Chinese Color Nest Consortium, ; Zuo, X.-N.
10.1101/2023.04.07.535977 — neuroscience — Posted on 2023-04-08
3046 Evolution of neuronal cell classes and types in the vertebrate retina
Hahn, J.; Monavarfeshani, A.; Qiao, M.; Kao, A.; Kölsch, Y.; Kumar, A.; Kunze, V. P.; Rasys, A. M.; Richardson, R.; Baier, H.; Lucas, R. J.; Li, W.; Meister, M.; Trachtenberg, J. T.; Yan, W.; Peng, Y.-R.; Sanes, J.; Shekhar, K.
10.1101/2023.04.07.536039 — neuroscience — Posted on 2023-04-08
3048 An AI-based segmentation and analysis pipeline for high-field MR monitoring of cerebral organoids
Deininger, L.; Jung-Klawitter, S.; Richter, P.; Fischer, M.; Karimian-Jazi, K.; Breckwoldt, M.; Bendszus, M.; Heiland, S.; Kleesiek, J.; Mikut, R.; Huebschmann, D.; Schwarz, D.
10.1101/2023.04.07.535822 — developmental biology — Posted on 2023-04-07
3049 Gasdermin D promotes influenza virus-induced mortality through neutrophil amplification of inflammation
Speaks, S.; Zani, A.; Solstad, A.; Kenney, A.; McFadden, M.; Zhang, L.; Eddy, A. C.; Amer, A. O.; Robinson, R.; Cai, C.; Ma, J.; Hemann, E.; Forero, A.; Yount, J.
10.1101/2023.03.08.531787 — immunology — Posted on 2023-04-08
3050 Virological characteristics of the SARS-CoV-2 Omicron XBB.1.16 variant
Yamasoba, D.; Uriu, K.; Plianchaisuk, A.; Kosugi, Y.; Pan, L.; Zahradnik, J.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Ito, J.; Sato, K.
10.1101/2023.04.06.535883 — microbiology — Posted on 2023-04-08
3052 Cortical activity emerges in region-specific patterns during early brain development
Suarez, R.; Bluett, T.; McCullough, M.; Avitan, L.; Black, D.; Paolino, A.; Fenlon, L.; Goodhill, G.; Richards, L. J.
10.1101/2023.02.18.529078 — neuroscience — Posted on 2023-04-08
3054 Comparison of shear stress patterns by the established and advanced reconstruction method incorporating side branches to predict plaque progression
Ramasamy, A.; Räber, L.; Tanboga, I. h.; Safi, H.; Hadjiandreou, M.; Sakellarios, A.; Kitslaar, P. H.; Dijkstra, J.; Biccire, F. G.; Crake, T.; Michalis, L. K.; Fotiadis, D.; Windecker, S.; Zhang, Y.-J.; Mathur, A.; Baumbach, A.; Torii, R.; Bourantas, C. V.
10.1101/2023.04.05.535789 — bioengineering — Posted on 2023-04-08
3055 Mechanistic basis for oxidative stress protection of the human tRNA ligase complex by the oxidoreductase PYROXD1
Loeff, L.; Kroupova, A.; Asanovic, I.; Boneberg, F. M.; Pfleiderer, M. M.; Ferdigg, A.; Ackle, F.; Martinez, J.; Jinek, M.
10.1101/2023.04.06.535761 — biochemistry — Posted on 2023-04-08
3056 Hagfish genome illuminates vertebrate whole genome duplications and their evolutionary consequences
Yu, D.; Ren, Y.; Uesaka, M.; Beavan, A. J. S.; Muffato, M.; Shen, J.; Li, Y.; Sato, I.; Wan, W.; Clark, J. W.; Keating, J. N.; Carlisle, E. M.; Dearden, R. P.; Giles, S.; Randle, E.; Sansom, R. S.; Feuda, R.; Fleming, J. F.; Sugahara, F.; Cummins, C.; Patricio, M.; Akanni, W.; D'Aniello, S.; Bertolucci, C.; Irie, N.; Alev, C.; Sheng, G.; de Mendoza, A.; Maeso, I.; Irimia, M.; Fromm, B.; Peterson, K. J.; Das, S.; Hirano, M.; Rast, J. P.; Cooper, M. D.; Paps, J.; Pisani, D.; Kuratani, S.; Martin, F. J.; Wang, W.; Donoghue, P. C. J.; Zhang, Y. E.; Pascual-Anaya, J.
10.1101/2023.04.08.536076 — genomics — Posted on 2023-04-08
3057 Broad functional profiling of fission yeast proteins using phenomics and machine learning
Rodriguez-Lopez, M.; Bordin, N.; Lees, J.; Scholes, H.; Hassan, S.; Saintain, Q.; Kamrad, S.; Orengo, C.; Bähler, J.
10.1101/2023.04.05.535764 — genetics — Posted on 2023-04-08
3059 Systematic mapping of chemoreceptor specificities for Pseudomonas aeruginosa
Sourjik, V.; Xu, W.; Cerna-Vargas, J. P.; Tajuelo, A.; Montoya, A. L.; Kivoloka, M.; Krink, N.; Monteagudo-Cascales, E.; Matilla, M. A.; Krell, T.
10.1101/2023.04.04.535651 — microbiology — Posted on 2023-04-08
3061 A new tractable method for generating Human Alveolar Macrophage Like cells in vitro to study lung inflammatory processes and diseases
Pahari, S.; Arnett, E.; Simper, J.; Azad, A.; Guerrero-Arguero, I.; Ye, C.; Zhang, H.; Cai, H.; Wang, Y.; Lai, Z.; Jarvis, N.; Lumbreras, M.; Maselli-Caceres, D. J.; Peters, J. I.; Torrelles, J. B.; Mart ínez-Sobrido, L.; Schlesinger, L. S.
10.1101/2023.04.05.535806 — immunology — Posted on 2023-04-08
3065 Doxorubicin inhibits phosphatidylserine decarboxylase and confers broad-spectrum antifungal activity
Zhou, Y.; Zhao, J.; Yang, L.; Bi, R.; Qin, Z.; Sun, P.; Li, R.; Zhao, M.; Wang, Y.; Chen, G.; Wan, H.; Zheng, L.; Wang, G.; Chen, X.-L.; Li, Q.; Li, G.
10.1101/2023.04.07.535992 — pathology — Posted on 2023-04-08
3067 Discovering functionally important sites in proteins
Cagiada, M.; Bottaro, S.; Lindemose, S.; Schenstrom, S. M.; Stein, A.; Hartmann-Petersen, R.; Lindorff-Larsen, K.
10.1101/2022.07.14.500015 — biophysics — Posted on 2023-04-08
3068 Protein homeostasis imprinting across evolution
Koutsandreas, T.; Felden, B.; Chevet, E.; Chatziioannou, A.
10.1101/2020.07.19.210591 — bioinformatics — Posted on 2023-04-08
3069 Magnetically Controlled Cyclic Microscale Deformation of in vitro Cancer Invasion Models
Asgeirsson, D. O.; Mehta, A.; Hesse, N.; Scheeder, A.; Ward, R.; Li, F.; Christiansen, M. G.; De Micheli, A.; Ildiz, E. S.; Aceto, N.; Schuerle, S.
10.1101/2023.03.30.534990 — bioengineering — Posted on 2023-04-08
3071 Finite Sample Adjustments for Average Equivalence Testing
Boulaguiem, Y.; Quartier, J.; Lapteva, M.; Kalia, Y. N.; Victoria-Feser, M.-P.; Guerrier, S.; Couturier, D.-L.
10.1101/2023.03.11.532179 — pharmacology and toxicology — Posted on 2023-04-08
3072 Topographic barriers drive the pronounced genetic subdivision of a range-limited fossorial rodent
Reuber, V. M.; Westbury, M. V.; Rey-Iglesia, A.; Asefa, A.; Farwig, N.; Miehe, G.; Opgenoorth, L.; Sumbera, R.; Wraase, L. M.; Wube, T.; Lorenzen, E. D.; Schabo, D. G.
10.1101/2023.04.06.535856 — evolutionary biology — Posted on 2023-04-07
3073 Gene interaction network analysis in multiple myeloma detects complex immune dysregulation associated with shorter survival
Simhal, A. K.; Maclachlan, K. H.; Elkin, R. H.; Zhu, J.; Norton, L.; Deasy, J. O.; Oh, J. H.; Usmani, S. Z.; Tannenbaum, A. R.
10.1101/2023.04.05.535155 — cancer biology — Posted on 2023-04-07
3075 Mitigating a TDP-43 proteinopathy using RNA-targeting CRISPR effector proteins
Zeballos C., M. A.; Moore, H. J.; Powell, J. E.; Smith, T. J.; Zhang, S.; Gaj, T.
10.1101/2023.04.07.536072 — bioengineering — Posted on 2023-04-08
3077 Reply to Barton et al: signatures of natural selection during the Black Death
Vilgalys, T. P.; Klunk, J.; Demeure, C. E.; Cheng, X.; Shiratori, M.; Madej, J.; Beau, R.; Elli, D.; Patino, M. I.; Redfern, R.; DeWitte, S. N.; Gamble, J.; Boldsen, J. L.; Carmichael, A.; Varlik, N.; Eaton, K.; Grenier, J.-C.; Golding, G. B.; Devault, A.; Rouillard, J.-M.; Yotova, V.; Sindeaux, R.; Ye, C. J.; Bikaran, M.; Dumaine, A.; Brinkworth, J. F.; Missiakas, D.; Rouleau, G. A.; Steinrücken, M.; Pizarro-Cerda, J.; Poinar, H.; Barreiro, L. B.
10.1101/2023.04.06.535944 — genomics — Posted on 2023-04-07
3078 Coding of time with non-linear mixed selectivity in Prefrontal Cortex ensembles
Mikkelsen, C.; Charczynski, S. J.; Warden, M. R.; Miller, E. K.; Howard, M.
10.1101/2023.04.07.535754 — neuroscience — Posted on 2023-04-07
3080 Alzheimer's disease-specific cytokine secretion suppresses neuronal mitochondrial metabolism
Kuhn, M. K.; Fleeman, R. M.; Beidler, L. M.; Snyder, A. M.; Chan, D. C.; Proctor, E. A.
10.1101/2023.04.07.536014 — neuroscience — Posted on 2023-04-07
3081 Photoreceptor disc incisures form as an adaptive mechanism ensuring the completion of disc enclosure
Lewis, T. R.; Phan, S.; Castillo, C. M.; Kim, K.-Y.; Coppenrath, K.; Thomas, W.; Hao, Y.; Skiba, N. P.; Horb, M. E.; Ellisman, M. H.; Arshavsky, V. Y.
10.1101/2023.04.06.535932 — cell biology — Posted on 2023-04-07
3082 Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon
Deng, P.; Tan, S.; Yang, Q.-Y.; Zhu, H.-Z.; Sun, L.; Bao, Z.; Lin, Y.; Cliff Zhang, Q.; Wang, J.; Liu, J.-J. G.
10.1101/2023.04.07.536001 — molecular biology — Posted on 2023-04-07
3084 Validation of a murine proteome-wide phage display library for the identification of autoantibody specificities
Rackaityte, E.; Proekt, I.; Miller, H. S.; Ramesh, A.; Brooks, J. F.; Kung, A. F.; Mandel-Brehm, C.; Yu, D.; Zamecnik, C.; Bair, R.; Vazquez, S. E.; Sunshine, S.; Abram, C. L.; Lowell, C. A.; Rizzuto, G.; Wilson, M. R.; Zikherman, J.; Anderson, M. S.; DeRisi, J. L.
10.1101/2023.04.07.535899 — immunology — Posted on 2023-04-07
3085 Interferon epsilon restricts Zika virus infection in the female reproductive tract
Xu, C.; Wang, A.; Ebraham, L.; Sullivan, L.; Tasker, C.; Pizutelli, V.; Couret, J.; Hernandez, C.; Deb, P. Q.; Fritzky, L.; Subbian, S.; Gao, N.; Lo, Y.; Salvatore, M.; Rivera, A.; Lemenze, A.; Fitzgerald-Bocarsly, P.; Tyagi, S.; Lu, W.; Beaulieu, A.; Chang, T. L.
10.1101/2023.04.06.535968 — immunology — Posted on 2023-04-07
3086 Uncovering circadian rhythm disruptions of synaptic proteome signaling in prefrontal cortex and nucleus accumbens associated with opioid use disorder
Puig, S.; Xue, X.; Salisbury, R.; Shelton, M. A.; Kim, S.-M.; Hildebrand, M. A.; Glausier, J. R.; Freyberg, Z.; Tseng, G. C.; Yocum, A. K.; Lewis, D. A.; Seney, M. L.; MacDonald, M. L.; Logan, R. W.
10.1101/2023.04.07.536056 — neuroscience — Posted on 2023-04-07
3088 A brain atlas of the camouflaging dwarf cuttlefish, Sepia bandensis
Montague, T. G.; Rieth, I. J.; Gjerswold-Selleck, S.; Garcia-Rosales, D.; Aneja, S.; Elkis, D.; Zhu, N.; Kentis, S.; Rubino, F. A.; Nemes, A.; Wang, K.; Hammond, L. A.; Emiliano, R.; Ober, R. A.; Guo, J.; Axel, R.
10.1101/2022.01.23.477393 — neuroscience — Posted on 2023-04-07
3089 Automated tumor immunophenotyping predicts clinical benefit from anti-PD-L1 immunotherapy
Li, X.; Eastham, J.; Giltnane, J. M.; Zou, W.; Zijlstra, A.; Tabatsky, E.; Banchereau, R.; Chang, C.-W.; Nabet, B.; Patil, N.; Molinero, L.; Chui, S.; Peterson, M.; Lau, S.; Rangell, L.; Waumans, Y.; Kockx, M.; Orlova, D.; Koeppen, H.
10.1101/2023.04.03.535467 — pathology — Posted on 2023-04-07
3090 Anti-tumor Efficacy of in situ Vaccination Using Bacterial Outer Membrane Vesicles
Caproni, E.; Corbellari, R.; Tomasi, M.; Isaac, S. J.; Tamburini, S.; Zanella, I.; Grigolato, M.; Gagliardi, A.; Benedet, M.; Baraldi, C.; Croia, L.; Di Lascio, G.; Valensin, S.; Bellini, E.; Parri, M.; Grandi, A.; Grandi, G.
10.1101/2023.04.07.536036 — cancer biology — Posted on 2023-04-07
3091 Real-time tracking of drug binding to Influenza A M2 reveals a high energy barrier
Tekwani Movellan, K.; Wegstroth, M.; Overkamp, K.; Leonov, A.; Becker, S.; Andreas, L. B.
10.1101/2023.04.07.536045 — biophysics — Posted on 2023-04-07
3093 Targeted RNA Condensation in Living Cells via Genetically Encodable Triplet Repeat Tags
Xue, Z.; Ren, K.; Wu, R.; Sun, Z.; Zheng, R.; Tian, Q.; Ali, A. A.; Mi, L.; You, M.
10.1101/2023.04.07.536084 — bioengineering — Posted on 2023-04-07
3094 Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics
Wallace, R. P.; Refvik, K. C.; Antane, J. T.; Brünggel, K.; Tremain, A. C.; Raczy, M. R.; Alpar, A. T.; Nguyen, M.; Solanki, A.; Slezak, A. J.; Watkins, E. A.; Lauterbach, A. L.; Wilson, D. S.; Hubbell, J. A.
10.1101/2023.04.07.534593 — bioengineering — Posted on 2023-04-07
3095 Mitigating a TDP-43 proteinopathy using RNA-targeting CRISPR effector proteins
Gaj, T.; Zeballos C., M. A.; Powell, J. E.; Smith, T. J.; Moore, H. J.; Zhang, S.
10.1101/2023.04.07.536072 — bioengineering — Posted on 2023-04-07
3097 Stepwise design of pseudosymmetric protein hetero-oligomers
Kibler, R. D.; Lee, S.; Kennedy, M. A.; Wicky, B. I. M.; Lai, S. M.; Kostelic, M. M.; Li, X.; Chow, C. M.; Carter, L.; Wysocki, V. H.; Stoddard, B. L.; Baker, D.
10.1101/2023.04.07.535760 — biochemistry — Posted on 2023-04-07
3099 bettercallsal: better calling of Salmonella serotypes from enrichment cultures using shotgun metagenomic profiling and its application in an outbreak setting.
Konganti, K.; Reed, E.; Mammel, M.; Kayikcioglu, T.; Binet, R.; Jarvis, K.; Ferreira, C.; Bell, R.; Zheng, J.; Windsor, A. M.; Ottesen, A.; Grim, C.; Ramachandran, P.
10.1101/2023.04.06.535929 — genomics — Posted on 2023-04-07
3101 The BTB-ZF gene Bm-mamo regulate pigmentation in caterpillars
Wu, S.; Tong, X.; Peng, C.; Lu, K.; Luo, J.; Li, C.; Zhang, C.; Ding, X.; Lu, Y.; Duan, X.; Hu, H.; Tan, D.; Dai, F.
10.1101/2023.04.07.536007 — genetics — Posted on 2023-04-07
3104 DRMY1 promotes robust morphogenesis by sustaining translation of a hormone signaling protein
Kong, S.; Zhu, M.; Scarpin, M. R.; Pan, D.; Jia, L.; Martinez, R. E.; Alamos, S.; Vadde, V. L.; Garcia, H. G.; Qian, S.-B.; Brunkard, J. O.; Roeder, A. H. K.
10.1101/2023.04.07.536060 — developmental biology — Posted on 2023-04-07
3105 Fatty links between multisystem proteinopathy and Small VCP-Interacting Protein
Ramzan, F.; Abrar, F.; Kumar, A.; Liao, L. M. Q.; Campbell, Z. E.; Gray, R. V.; Akanni, O.; Guyn, C. M.; Martin, D. D. O.
10.1101/2023.03.31.531359 — cell biology — Posted on 2023-04-07
3109 Rapid-kinetics degron benchmarking reveals off-target activities and mixed agonism-antagonism of MYB inhibitors
Harada, T.; Perez, M. W.; Kalfon, J.; Dievenich Braes, F.; Batley, R.; Eagle, K.; Nabet, B.; Leifer, B.; Kruell, J.; Paralkar, V. R.; Stegmaier, K.; Koehler, A. N.; Orkin, S. H.; Pimkin, M.
10.1101/2023.04.07.536032 — molecular biology — Posted on 2023-04-07
3110 High-resolution cryo-electron microscopy of the human CDK-activating kinase for structure-based drug design
Cushing, V. I.; Koh, A. F.; Feng, J.; Jurgaityte, K. T.; Bahl, A. K.; Ali, S.; Kotecha, A.; Greber, B. J.
10.1101/2023.04.07.536029 — molecular biology — Posted on 2023-04-07
3111 Emergence and rapid dissemination of highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b in wild birds, Chile.
Ariyama, N.; Pardo Roa, C.; Munoz, G.; Aguayo, C.; Avila, C.; Mathieu, C.; Brito, B.; Medina, R.; Johow, M.; Neira-Ramirez, V.
10.1101/2023.04.07.535949 — microbiology — Posted on 2023-04-07
3115 A correlative study of the genomic underpinning of virulence traits and drug tolerance of Candida auris
Yang, B.; Vaisvil, B.; Schmitt, D.; Collins, J. H.; Young, E. M.; Kapatral, V.; Rao, R. P.
10.1101/2023.04.07.536049 — microbiology — Posted on 2023-04-07
3118 Loss of Gasdermin D is protective against influenza virus-induced inflammation and mortality
Speaks, S.; Zani, A.; Solstad, A.; Kenney, A.; McFadden, M.; Zhang, L.; Eddy, A. C.; Amer, A. O.; Robinson, R.; Cai, C.; Ma, J.; Hemann, E.; Forero, A.; Yount, J.
10.1101/2023.03.08.531787 — immunology — Posted on 2023-04-07
3120 Bridging Big Data: Procedures for Combining Non-equivalent Cognitive Measures from the ENIGMA Consortium
Kennedy, E.; Vadlamani, S.; Lindsey, H. M.; Lei, P.-W.; Pugh, M. J.; Adamson, M.; Alda, M.; Alonso-Lana, S.; Ambrogi, S.; Anderson, T. J.; Arango, C.; Asarnow, R.; Avram, M.; Ayesa-Arriola, R.; Babikian, T.; Banaj, N.; Bird, L. J.; Borgwardt, S.; Brodtmann, A.; Brosch, K.; Caeyenberghs, K.; Calhoun, V. D.; Chiaravalloti, N. D.; Cifu, D. X.; Crespo-Facorro, B.; Dalrymple-Alford, J. C.; Dams-O'Connor, K.; Dannlowski, U.; Darby, D.; Davenport, N.; DeLuca, J.; Diaz-Caneja, C. M.; Disner, S. G.; Dobryakova, E.; Ehrlich, S.; Esopenko, C.; Ferrarelli, F.; Frank, L. E.; Franz, C.; Fuentes-Claramonte,
10.1101/2023.01.16.524331 — neuroscience — Posted on 2023-04-07
3122 The pGinger family of expression plasmids
Pearson, A. N.; Thompson, M.; Kirkpatrick, L.; Ho, C.; Vuu, K. M.; Waldburger, L.; Keasling, J. D.; Shih, P. M.
10.1101/2023.01.23.524619 — synthetic biology — Posted on 2023-04-07
3124 Decoding the Cure-all Effects of Ginseng
Loo, S.; Kam, A.; Dutta, B.; Zhang, X.; Feng, N.; Sze, S. K.; Liu, C.-F.; Wang, X.; Tam, J. P.
10.1101/2023.04.05.535784 — pharmacology and toxicology — Posted on 2023-04-07
3126 Computational Scoring and Experimental Evaluation of Enzymes Generated by Neural Networks
Johnson, S. R.; Fu, X.; Viknander, S.; Goldin, C.; Monaco, S.; Zelezniak, A.; Yang, K. K.
10.1101/2023.03.04.531015 — biochemistry — Posted on 2023-04-07
3127 The central nervous system is a potential reservoir and possible origin of drug resistance in HBV
Xu, L.; Zhou, M.; Peng, X.; Xu, Y.; Huang, F.; Wang, L.; peng, x.; Yang, Z.; Tao, R.; Lang, G.; Cao, Q.; Li, M.; Huang, Y.; Zhu, B.; Xu, Y.
10.1101/2023.04.05.535804 — evolutionary biology — Posted on 2023-04-07
3131 Phytohormone profiling in an evolutionary framework
Schmidt, V.; Skokan, R.; Kurtovic, K.; Vosolsobe, S.; Filepova, R.; Haluska, S.; Dobrev, P.; Motyka, V.; Petrasek, J.
10.1101/2023.04.06.534998 — plant biology — Posted on 2023-04-07
3132 A resampling-based approach to share reference panels
Cavinato, T.; Rubinacci, S.; Malaspinas, A.-S.; Delaneau, O.
10.1101/2023.04.07.535812 — bioinformatics — Posted on 2023-04-07
3134 High-density microbioreactor process designed for automated point-of-care manufacturing of CAR T cells
Sin, W.-X.; Jagannathan, N. S.; Teo, D. B. L.; Kairi, F.; Sandikin, D.; Cheung, K.-W.; Lee, Y. H.; Ram, R. J.; Tucker-Kellogg, L.; Birnbaum, M. E.
10.1101/2023.04.07.535939 — bioengineering — Posted on 2023-04-07
3135 Systematic visualisation of molecular QTLs reveals variant mechanisms at GWAS loci
Kerimov, N.; Tambets, R.; Hayhurst, J. D.; Rahu, I.; Kolberg, P.; Raudvere, U.; Kuzmin, I.; Chowdhary, A.; Vija, A.; Teras, H. J.; Kanai, M.; Ulirsch, J.; Ryten, M.; Hardy, J.; Guelfi, S.; Trabzuni, D.; Kim-Hellmuth, S.; Rayner, W.; Finucane, H.; Peterson, H.; Mosaku, A.; Parkinson, H.; Alasoo, K.
10.1101/2023.04.06.535816 — genomics — Posted on 2023-04-07
3136 Gut barrier defects, increased intestinal innate immune response, and enhanced lipid catabolism drive lethality in N-glycanase 1 deficient Drosophila
Pandey, A.; Galeone, A.; Han, S. Y.; Story, B. A.; Consonni, G.; Mueller, W. F.; Steinmetz, L. M.; Vaccari, T.; Jafar-Nejad, H.
10.1101/2023.04.07.536022 — developmental biology — Posted on 2023-04-07
3137 Detailed Social Network Interactions and Gut Microbiome Strain-Sharing Within Isolated Honduras Villages
Pullman, J.; Beghini, F.; Alexander, M.; Vishnempet Shridhar, S.; Prinster, D.; Brito, I. L.; Christakis, N. A.
10.1101/2023.04.06.535875 — microbiology — Posted on 2023-04-07
3138 Silymarin Inhibits In Vitro SARS-CoV-2 Infection In Vero E6 Cells
Nnadi, N. E.; Luka, P. D.; Omale, S.; Shehu, N. Y.; Aguiyi, J. C.
10.1101/2023.04.07.535766 — microbiology — Posted on 2023-04-07
3142 Low-dose cytokine immunotherapy of solid cancers enabled by phagocytic-competent protein co-crystals
Jones, M. H.; Quispe Calla, N. E.; Smith, R.; Talbot Cooper, C.; Rudge, S.; Kusano, H.; Shiomi, T.; Ishikawa, Y.; Zeng, H.; Best, J. D.
10.1101/2023.04.06.534711 — cancer biology — Posted on 2023-04-07
3144 Microalgae as a novel biofactory for biocompatible and bioactive extracellular vesicles
Adamo, G.; Santonicola, P.; Picciotto, S.; Gargano, P.; Nicosia, A.; Longo, V.; Aloi, N.; Romancino, D. P.; Paterna, A.; Rao, E.; Raccosta, S.; Noto, R.; Salamone, M.; Costa, S.; Di Sano, C.; Zampi, G.; Colombo, P.; Wei, M.; Touzet, N.; Manno, M.; Di Schiavi, E.; Bongiovanni, A.
10.1101/2023.04.04.535547 — cell biology — Posted on 2023-04-07
3146 Control of working memory maintenance by theta-gamma phase amplitude coupling of human hippocampal neurons
Daume, J.; Kaminski, J.; Schjetnan, A. G. P.; Salimpour, Y.; Khan, U.; Reed, C. M.; Anderson, W. S.; Valiante, T. A.; Mamelak, A. N.; Rutishauser, U.
10.1101/2023.04.05.535772 — neuroscience — Posted on 2023-04-07
3147 High-THC Cannabis smoke impairs working memory capacity in spontaneous tests of novelty preference for objects and odors in rats
Barnard, I. L.; Onofrychuk, T. J.; Toderash, A. D.; Patel, V. N.; Glass, A. E.; Adrian, J. C.; Laprairie, R. B.; Howland, J. G.
10.1101/2023.04.06.535880 — neuroscience — Posted on 2023-04-07
3148 Monosynaptic inputs to ventral tegmental area glutamate and GABA co-transmitting neurons
Prevost, E. D.; Phillips, A.; Lauridsen, K.; Enserro, G.; Rubinstein, B.; Alas, D.; McGovern, D. J.; Ly, A.; Banks, M.; McNulty, C. J.; Kim, Y. S.; Fenno, L. E.; Ramakrishnan, C. H.; Deisseroth, K.; Root, D. H.
10.1101/2023.04.06.535959 — neuroscience — Posted on 2023-04-07
3149 Primary Somatosensory Cortex Bidirectionally Modulates Sensory Gain and Nociceptive Behavior in a Layer-Specific Manner
Ziegler, K.; Burghardt, J.; Folkard, R.; Gonzalez, A.; Antharvedi-Goda, S.; Martin-Cortecero, J.; Isaias-Camacho, E.; Kaushalya, S.; Tan, L. L.; Kuner, T.; Acuna, C.; Kuner, R.; Mease, R.; Groh, A.
10.1101/2022.08.02.502350 — neuroscience — Posted on 2023-04-07
3152 A rapid, low cost, and highly sensitive SARS-CoV-2 diagnostic based on whole genome sequencing
Adastra, P. A.; Durand, N. C.; Mitra, N.; Godinez, S.; Mahajan, R.; Blackburn, A.; Colaric, Z.; Theisen, J. W.; Weisz, D.; Dudchenko, O.; Gnirke, A.; Rao, S. S. P.; Kaur, P.; Aiden, E.; Aiden, A.
10.1101/2020.04.25.061499 — genomics — Posted on 2023-04-07
3154 RIF1 regulates replication origin activity and early replication timing in B cells
Malzl, D.; Peycheva, M.; Rahjouei, A.; Gnan, S.; Klein, K.; Nazarova, M.; Schoeberl, U. E.; Gilbert, D. M.; Buonomo, S. C. B.; Di Virgilio, M.; Neumann, T.; Pavri, R.
10.1101/2023.03.31.535086 — genetics — Posted on 2023-04-07
3156 Methotrexate-modulated talin-dynamics drives cellular mechanical phenotypes via YAP signalling
Chowdhury, D.; Dhabal, S.; Bhatt, M.; Maity, D.; Chakraborty, S.; Priyadarshi, S.; Haldar, S.
10.1101/2023.04.07.535979 — cell biology — Posted on 2023-04-07
3157 Emerging Antifungal Resistance in Falco Species: A Novel Model for Human Medicine
Das, S.; Christu, S. D.; Silvanose, C.; Binoy, A.; Azmanis, P.; Di Somma, A.; Gladston, J. V.
10.1101/2023.03.22.533837 — microbiology — Posted on 2023-04-07
3160 Overactivated epithelial NF-κB disrupts lung development in human and nitrofen CDH
Dylong, F.; Riedel, J.; Amonkar, G. M.; Peukert, N.; Lieckfeldt, P.; Sturm, K.; Hoexter, B.; Tse, W. H.; Miyake, Y.; Mayer, S.; Keijzer, R.; Lacher, M.; Ai, X.; Gosemann, J. H.; Wagner, R.
10.1101/2023.04.07.536002 — developmental biology — Posted on 2023-04-07
3164 Comparative 3D ultrastructure of Plasmodium falciparum gametocytes
Evers, F.; Roverts, R.; Boshoven, C.; Kea-te Lindert, M.; Verhoef, J. M.; Sinden, R. E.; Akiva, A.; Kooij, T. W. A.
10.1101/2023.03.10.531920 — microbiology — Posted on 2023-04-07
3167 Global analysis of suppressor mutations that rescue human genetic defects
Ünlü, B.; Pons, C.; Ho, U. L.; Batte, A.; Aloy, P.; van Leeuwen, J.
10.1101/2022.11.09.515781 — genomics — Posted on 2023-04-07
3168 The BOD1L subunit of the mammalian SETD1A complex sustains the expression of DNA damage repair genes despite restraining H3K4 trimethylation
Ciotta, G.; Singh, S.; Gupta, A.; Torres, D. C.; Fu, J.; Choudhury, R.; Chu, W. K.; Choudhary, C.; Gahurova, L.; Al-Fatlawi, A.; Schroeder, M.; Aasland, R.; Poetsch, A. R.; Anastassiadis, K.; Stewart, A. F.
10.1101/2023.04.06.535882 — cell biology — Posted on 2023-04-07
3170 Elevated CD153 Expression on Aged T Follicular Helper Cells is Vital for B cell Responses
Thomas, A. L.; Wayman, J. A.; Almanan, M.; Bejjani, A. T.; Miraldi, E.; Chougnet, C. A.; Hildeman, D.
10.1101/2023.03.17.533214 — immunology — Posted on 2023-04-07
3171 Brainstem fMRI signaling of surprise across different types of deviant stimuli
Mazancieux, A.; Mauconduit, F.; Amadon, A.; de Gee, J. W.; Donner, T.; Meyniel, F.
10.1101/2022.07.25.501374 — neuroscience — Posted on 2023-04-07
3174 Cell polarity linked to gravity sensing is generated by protein translocation from statoliths to the plasma membrane.
Nishimura, T.; Mori, S.; Shikata, H.; Nakamura, M.; Hashiguchi, Y.; Abe, Y.; Hagihara, T.; Yoshikawa, H. Y.; Toyota, M.; Higaki, T.; Morita, M. T.
10.1101/2023.03.31.534658 — plant biology — Posted on 2023-04-07
3175 Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation
Juyoux, P.; Galdadas, I.; Gobbo, D.; von Velsen, J.; Pelosse, M.; Tully, M.; Vadas, O.; Gervasio, F. L.; Pellegrini, E.; Bowler, M. W.
10.1101/2022.07.04.498667 — biophysics — Posted on 2023-04-07
3177 StocSum: stochastic summary statistics for whole genome sequencing studies
Wang, N.; Yu, B.; Jun, G.; Qi, Q.; Durazo-Arvizu, R. A.; Lindstrom, S.; Morrison, A.; Kaplan, R. C.; Boerwinkle, E.; Chen, H.
10.1101/2023.04.06.535886 — genetics — Posted on 2023-04-07
3179 Emergence of belief-like representations through reinforcement learning
Hennig, J.; Romero Pinto, S. A.; Yamaguchi, T.; Linderman, S. W.; Uchida, N.; Gershman, S. J.
10.1101/2023.04.04.535512 — neuroscience — Posted on 2023-04-07
3182 Characterization of walking locomotion in aged C57BL/10 mice: a comprehensive gait analysis
Rizzi, J. S.; Almeida, C. d. B.; Requena, L. S.; de Almeida, V. D.; Mininel, T. V.; da Silva, G. L. L.; de Oliveira, P. F.; de Castro e Horta Junior, J. d. A.; Matsumura, C. Y.; Ferretti, R.
10.1101/2023.04.04.535545 — animal behavior and cognition — Posted on 2023-04-07
3183 Lessons from relatives: C4 photosynthesis enhances CO2 assimilation during the low-light phase of fluctuations.
Kromdijk, J.; Arce Cubas, L.; Rodrigues Gabriel Sales, C.; Vath, R. L.; Bernardo, E. L.; Burnett, A. C.
10.1101/2023.04.03.535443 — plant biology — Posted on 2023-04-07
3184 A rapid microglial metabolic response controls metabolism and improves memory
Drougard, A.; Ma, E. H.; Wegert, V.; Sheldon, R.; Panzeri, I.; Vatsa, N.; Apostle, S.; Fagnocchi, L.; Schaf, J.; Gossens, K.; Völker, J.; Pang, S.; Bremser, A.; Dror, E.; Giacona, F.; Sagar, ; Henderson, M. X.; Prinz, M.; Jones, R. G.; Pospisilik, J. A.
10.1101/2023.04.03.535373 — physiology — Posted on 2023-04-07
3187 The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 Gamma variant
Pegg, C. L.; Modhiran, N.; Parry, R.; Liang, B.; Amarilla, A. A.; Khromykh, A.; Burr, L.; Young, P.; Chappell, K.; Schulz, B. L.; Watterson, D.
10.1101/2023.04.03.535004 — biochemistry — Posted on 2023-04-07
3188 ApoA-I Protects Pancreatic β-cells from Cholesterol-induced Mitochondrial Damage and Restores their Ability to Secrete Insulin
Manandhar, B.; Pandzic, E.; Deshpande, N.; Chen, S.-Y.; Wasinger, V.; Kockx, M.; Glaros, E. N.; Ong, K. L.; Thomas, S. R.; Wilkins, M.; Whan, R.; Cochran, B. J.; Rye, K.-A.
10.1101/2023.04.03.535492 — cell biology — Posted on 2023-04-07
3189 Longitudinal study of humoral immunity against SARS-CoV-2 of health professionals in Brazil: the impact of booster dose and reinfection on antibody dynamics
Franco-Luiz, A. P.; Fernandes, N. M. G. S.; Silva, T. B. d. S.; Bernardes, W. P. d. O. S.; Westin, M. R.; Santos, T. G.; Fernandes, G. R.; Simoes, T. C.; Fernandes e Silva, E.; Gava, S. G.; Alves, B. M.; Melo, M. d. C.; Silva-Pereira, R. A. d.; Alves, P. A.; Toscano Fonseca, C.
10.1101/2023.04.03.535504 — microbiology — Posted on 2023-04-07
3190 Glycolytic imprinting of monocytes impairs HIF1α-driven migration of dendritic cells in tuberculosis
Maio, M.; Joly, M.; Vahlas, Z.; Barros, J.; Marin Franco, J. L.; Genoula, M.; Monard, S.; Vecchione, M. B.; Fuentes, F.; Gonzalez Polo, V.; Quiroga, M. F.; Vermeulen, M.; Argüello, R. J.; Inwentarz, S.; Musella, R.; Ciallella, L.; Gonzalez Montaner, P.; Palmero, D.; Lugo Villarino, G.; Sasiain, M. d. C.; Neyrolles, O.; Verolle, C.; Balboa, L.
10.1101/2023.04.03.535400 — immunology — Posted on 2023-04-07
3191 Multicellular, IVT-derived, unmodified human transcriptome for nanopore direct RNA analysis
McCormick, C. A.; Akeson, S.; Tavakoli, S.; Bloch, D.; Klink, I. N.; Jain, M.; Rouhanifard, S. H.
10.1101/2023.04.06.535889 — genomics — Posted on 2023-04-07
3194 Tools and methods for high-throughput single-cell imaging with the mother machine
Thiermann, R.; Sandler, M.; Ahir, G.; Sauls, J. T.; Schroeder, J. W.; Brown, S. D.; Le Treut, G.; Si, F.; Li, D.; Wang, J.; Jun, S.
10.1101/2023.03.27.534286 — systems biology — Posted on 2023-04-07
3195 euka: Robust detection of eukaryotic taxa from modern and ancient environmental DNA using pangenomic reference graphs.
Vogel, N. A.; Rubin, J. D.; Swartz, M.; Vlieghe, J.; Sackett, P. W.; Pedersen, A. G.; Pedersen, M. W.; Renaud, G.
10.1101/2023.04.04.535531 — bioinformatics — Posted on 2023-04-07
3198 The Achromobacter Type 3 secretion system drives pyroptosis and immunopathology via independent activation of NLRC4 and NLRP3 inflammasomes
Turton, K.; Parks, H.; Zarodkiewicz, P.; Hamad, M. A.; Dwane, R.; Parau, G.; Ingram, R. J.; Coll, R. C.; Bryant, C. E.; Valvano, M. A.
10.1101/2023.04.06.535904 — microbiology — Posted on 2023-04-06
3199 TREM2 mediates MHCII-associated CD4+ T cell response against gliomas
Zheng, J.; Wang, L.; Zhao, S.; Zhang, W.; Chang, Y.; Dheer, A.; Gao, S.; Xu, S.; Ayasoufi, K.; Al-kharboosh, R.; Xie, M.; Johnson, A. J.; Dong, H.; Quinones-Hinojosa, A.; Wu, L.-J.
10.1101/2023.04.05.535697 — neuroscience — Posted on 2023-04-06
3200 FMRP regulates neuronal migration via MAP1B
Messaoudi, S.; Stoufflet, J.; Fouquet, C.; Doulazmi, M.; Allam, A.; Paillard, T.; Trembleau, A.; Caille, I.
10.1101/2023.03.06.530447 — neuroscience — Posted on 2023-04-06
3201 Precise Spatial Tuning of Visually Driven Alpha Oscillations in Human Visual Cortex
Yuasa, K.; Groen, I. I. A.; Piantoni, G.; Montenegro, S.; Flinker, A.; Devore, S.; Devinsky, O.; Doyle, W.; Dugan, P.; Friedman, D.; Ramsey, N.; Petridou, N.; Winawer, J.
10.1101/2023.02.11.528137 — neuroscience — Posted on 2023-04-06
3202 Stablization of Interdomain Interactions in G protein αi Subunits Determines Gαi Subtype Signaling Specificity
Lefevre, T.; Wei, W.; Mukhaleva, E.; Venkata, S. P. M.; Chandan, N. R.; Abraham, S.; Li, Y.; Dessauer, C. W.; Vaidehi, N.; Smrcka, A.
10.1101/2023.03.10.532072 — pharmacology and toxicology — Posted on 2023-04-06
3203 A Rapid, Functional sgRNA Screening Method for Generating Murine RET and NTRK1 Fusion Oncogenes
Heasley, L. E.; Schubert, L.; Le, A. T.; Hinz, T. K.; Navarro, A.; Nelson-Taylor, S. K.; Nemenoff, R. A.; Doebele, R. C.
10.1101/2023.04.06.535912 — cancer biology — Posted on 2023-04-06
3205 Sequence-encoded grammars determine material properties and physical aging of protein condensates
Alshareedah, I.; Borcherds, W. M.; Cohen, S. R.; Farag, M.; Singh, A.; Bremer, A.; Pappu, R. V.; Mittag, T.; Banerjee, P. R.
10.1101/2023.04.06.535902 — biophysics — Posted on 2023-04-06
3206 Septins Provide Microenvironment Sensing and Cortical Actomyosin Partitioning in Motile Amoeboid T Lymphocytes
Zhovmer, A. S.; Manning, A.; Smith, C.; Saez, P. J.; Ma, X.; Tsygankov, D.; Cartagena-Rivera, A. X.; Singh, R. K.; Tabdanov, E. D.
10.1101/2022.01.18.476840 — biophysics — Posted on 2023-04-06
3207 Data driven and cell specific determination of nuclei-associated actin structure
Nikitina, N.; Bursa, N.; Goelzer, M.; Goldfeldt, M.; Crandall, C.; Howard, S.; Rubin, J.; Satici, A.; Uzer, G.
10.1101/2023.04.06.535937 — bioengineering — Posted on 2023-04-06
3208 Butyrate prevents visceral adipose tissue inflammation and metabolic alterations in a mouse model of Friedreich's ataxia
TURCHI, R.; SCIARRETTA, F.; TIBERI, M.; AUDANO, M.; PEDRETTI, S.; PANEBIANCO, C.; NESCI, V.; PAZIENZA, V.; FERRI, A.; CAROTTI, S.; CHIURCHIU', V.; MITRO, N.; LETTIERI-BARBATO, D.; AQUILANO, K.
10.1101/2023.04.06.535845 — biochemistry — Posted on 2023-04-06
3211 Correcting PCR amplification errors in unique molecular identifiers to generate absolute numbers of sequencing molecules.
Sun, J.; Philpott, M.; Loi, D.; Li, S.; Monteagudo-Mesas, P.; Hoffman, G.; Robson, J.; Mehta, N.; Gamble, V.; Brown, T.; Brown, T.; Canzar, S.; Oppermann, U.; Cribbs, A. P.
10.1101/2023.04.06.535911 — genomics — Posted on 2023-04-06
3214 Juvenile hormones direct primordial germ cell migration to the embryonic gonad
Barton, L.; Sanny, J.; Dawson, E. P.; Nouzova, M.; Noriega, F. G.; Stadtfeld, M.; Lehmann, R.
10.1101/2021.09.30.462471 — developmental biology — Posted on 2023-04-06
3215 METTL3 is essential for small intestinal epithelial proliferation via regulation of growth factor signaling including KRAS
Danan, C. H.; Naughton, K. E.; Hayer, K. E.; Vellapan, S.; McMillan, E. A.; Zhou, Y.; Matsuda, R.; Nettleford, S. K.; Katada, K.; Parham, L. R.; Ma, X.; Chowdhury, A.; Wilkins, B. J.; Shah, P.; Weitzman, M. D.; Hamilton, K. E.
10.1101/2023.04.06.535853 — cell biology — Posted on 2023-04-06
3216 Identification of LMAN1 and SURF4 dependent secretory cargoes
Tang, V. T.; Abbineni, P. S.; da Veiga Leprevost, F.; Basrur, V.; Emmer, B. T.; Nesvizhskii, A.; Ginsburg, D.
10.1101/2023.04.06.535922 — cell biology — Posted on 2023-04-06
3219 Virological characteristics of the SARS-CoV-2 Omicron XBB.1.16 variant
Yamasoba, D.; Uriu, K.; Plianchaisuk, A.; Kosugi, Y.; Pan, L.; Zahradnik, J.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Ito, J.; Sato, K.
10.1101/2023.04.06.535883 — microbiology — Posted on 2023-04-06
3220 The microbiota and immune system non-genetically affect offspring phenotypes transgenerationally
Harris, J. C.; Trigg, N. A.; Goshu, B.; Yokoyama, Y.; Dohnalova, L.; White, E. K.; Harman, A.; Thaiss, C. A.; Grice, E. A.; Conine, C. C.; Kambayashi, T.
10.1101/2023.04.06.535940 — microbiology — Posted on 2023-04-06
3222 Parallelized screening of virus accessory genes reveals diverse defense and counter-defense mechanisms
Silas, S.; Carion, H.; Makarova, K. S.; Laderman, E.; Godinez, D. S.; Johnson, M.; Fossati, A.; Swaney, D.; Bocek, M.; Koonin, E. V.; Bondy-Denomy, J.
10.1101/2023.04.06.535777 — microbiology — Posted on 2023-04-06
3225 Interferon-gamma is Quintessential for NOS and COX Expression in ER- Breast Tumors that Lead to Poor Outcome
Cheng, R. Y.; Ridnourl, L. A.; Wink, A. L.; Gonzalez, A. L.; Femino, E. L.; Rittscher, H.; Somasundarum, V.; Heinz, W. F.; Coutinho, L.; Rangel, C.; Edmondson, E. f.; Butcher, D.; Kinders, R. J.; Li, X.; Wong, S. T.; McVicar, D. W.; Anderson, S. K.; Pore, M.; Hewitt, S. M.; Billiar, T. R.; Glynn, S.; Chang, J. C.; Lockett, S. J.; Ambs, S.; Wink, D. A.
10.1101/2023.04.06.535916 — cancer biology — Posted on 2023-04-06
3226 Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing
Hatanaka, F.; Suzuki, K.; Shojima, K.; Yu, J.; Takahashi, Y.; Sakamoto, A.; Prieto, J.; Shokhirev, M.; Esteban, C. R.; Nunez-Delicado, E.; Belmonte, J. C. I.
10.1101/2023.04.06.535786 — bioengineering — Posted on 2023-04-06
3227 SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in mice
Alhammad, Y. M.; Parthasarathy, S.; Ghimire, R.; O'Connor, J. J.; Kerr, C. M.; Pfannenstiel, J. J.; Chanda, D.; Miller, C. A.; Unckless, R.; Zuniga, S.; Enjuanes, L.; More, S.; Channappanavar, R.; Fehr, A.
10.1101/2023.04.06.535927 — microbiology — Posted on 2023-04-06
3228 Strain-specific changes in nucleus accumbens transcriptome and motivation for food reward in mice exposed to maternal separation
Henry, M.; Fneich, S.; Mathou, A.; Xia, L.; Foury, A.; Benoit, S.; Jouin, M.; Junien, C.; Capuron, L.; Jouneau, L.; Moisan, M.-P.; Delpierre, C.; Gabory, A.; Darnaudery, M.
10.1101/2023.04.06.535855 — neuroscience — Posted on 2023-04-06
3229 Time-of-day-dependent variation of the hepatic transcriptome and metabolome is disrupted in non-alcoholic fatty liver disease patients
JOHANNS, M.; HAAS, J. T.; RAVERDY, V.; VANDEL, J.; CHEVALIER-DUBOIS, J.; GUILLE, L.; DERUDAS, B.; LEGENDRE, B.; CAIAZZO, R.; VERKINDT, H.; GNEMMI, V.; LETEURTRE, E.; DERHOUDI, M.; BONNEFOND, A.; FROGUEL, P.; Eeckhoute, J.; LASSAILLY, G.; MATHURIN, P.; PATTOU, F.; Staels, B.; LEFEBVRE, P.
10.1101/2023.04.05.535334 — genomics — Posted on 2023-04-06
3230 Multi-omic analysis of CIC's functional networks reveals novel interaction partners and a potential role in mitotic fidelity
Takemon, Y.; LeBlanc, V. G.; Song, J.; Chan, S. Y.; Lee, S. D.; Trinh, D. L.; Ahmad, S. T.; Brothers, W. R.; Corbett, R. D.; Gagliardi, A.; Moradian, A.; Cairncross, J. G.; Yip, S.; Aparicio, S. A.; Chan, J. A.; Hughes, C. S.; Morin, G. B.; Gorski, S. M.; Chittaranjan, S.; Marra, M. A.
10.1101/533323 — cancer biology — Posted on 2023-04-06
3231 Human USP18 protects diverse cancer lineages from Type I Interferon independently of its canonical catalytic function
Jove, V.; Wheeler, H.; Lee, C. W.; Healy, D. R.; Levine, K.; Ralph, E. C.; Yang, B.; Giddabasappa, A.; Loria, P.; Yamaguchi, M.; Casimiro-Garcia, A.; Kessler, B. M.; Pinto-Fernandez, A.; Frattini, V.; Wes, P. D.; Wang, F.
10.1101/2023.03.23.533924 — cancer biology — Posted on 2023-04-06
3233 Metabolic signatures of cardiorenal dysfunction in plasma from sickle cell patients, as a function of therapeutic transfusion and hydroxyurea treatment
D'Alessandro, A.; Nouraie, M.; Zhang, Y.; Cendali, F.; Gamboni, F.; Reisz, J. A.; Zhang, X.; Bartsch, K. W.; Galbraith, M. D.; Espinosa, J. M.; Gordeuk, V. R.; Gladwin, M. T.
10.1101/2023.04.05.535693 — biochemistry — Posted on 2023-04-06
3234 The Allen Ancient DNA Resource (AADR): A curated compendium of ancient human genomes
Mallick, S.; Micco, A.; Mah, M.; Ringbauer, H.; Lazaridis, I.; Olalde, I.; Patterson, N. J.; Reich, D. E.
10.1101/2023.04.06.535797 — genomics — Posted on 2023-04-06
3238 Learning from unexpected events in the neocortical microcircuit
Gillon, C. J.; Pina, J. E.; Lecoq, J.; Ahmed, R.; Billeh, Y. N.; Caldejon, S.; Groblewski, P.; Henley, T. M.; Kato, I.; Lee, E.; Luviano, J.; Mace, K.; Nayan, C.; Nguyen, T. V.; North, K.; Perkins, J.; Seid, S.; Valley, M. T.; Williford, A.; Bengio, Y.; Lillicrap, T. P.; Richards, B. A.; Zylberberg, J.
10.1101/2021.01.15.426915 — neuroscience — Posted on 2023-04-06
3240 Control of working memory maintenance by theta-gamma phase amplitude coupling of human hippocampal neurons
Daume, J.; Kaminski, J.; Schjetan, A. G. P.; Salimpour, Y.; Khan, U.; Reed, C.; Anderson, W.; Valiante, T. A.; Mamelak, A. N.; Rutishauser, U.
10.1101/2023.04.05.535772 — neuroscience — Posted on 2023-04-06
3243 Amphiphiles formed from synthetic DNA-nanomotifs mimic the step-wise dispersal of transcriptional clusters in the cell nucleus
Tschurikow, X.; Gadzekpo, A.; Tran, M. P.; Chatterjee, R.; Sobucki, M.; Zaburdaev, V.; Goepfrich, K.; Hilbert, L.
10.1101/2023.01.29.525851 — synthetic biology — Posted on 2023-04-06
3245 On the evolution of the plant phytochrome chromophore biosynthesis
Frascogna, F.; Ledermann, B.; Hartmann, J.; Perez Patallo, E.; Zeqiri, F.; Hofmann, E.; Frankenberg-Dinkel, N.
10.1101/2022.08.22.504806 — plant biology — Posted on 2023-04-06
3246 Impaired intracellular Ca2+ signaling contributes to age-related cerebral small vessel disease in Col4a1 mutant mice
Yamasaki, E.; Thakore, P.; Ali, S.; Solano, A. S.; Wang, X.; Gao, X.; Labelle-Dumais, C.; Chaumeil, M. M.; Gould, D. B.; Earley, S.
10.1101/2022.08.24.505186 — pathology — Posted on 2023-04-06
3248 StocSum: stochastic summary statistics for whole genome sequencing studies
Wang, N.; Yu, B.; Jun, G.; Qi, Q.; Durazo-Arvizu, R. A.; Lindstroem, S.; Morrison, A.; Kaplan, R. C.; Boerwinkle, E.; Chen, H.
10.1101/2023.04.06.535886 — genetics — Posted on 2023-04-06
3250 The BOD1L subunit of the mammalian SETD1A complex sustains the expression of DNA damage repair genes despite restraining H3K4 trimethylation
Ciotta, G.; Singh, S.; Gupta, A.; Torres, D. C.; Fu, J.; Choudhury, R.; Chu, W. K.; Choudhary, C.; Gahurova, L.; Al-Fatlawi, A.; Schroeder, M.; Aasland, R.; Poetsch, A.; Anastassiadis, K.; Stewart, A. F.
10.1101/2023.04.06.535882 — cell biology — Posted on 2023-04-06
3253 Resistance Training Diminishes Mitochondrial Adaptations to Subsequent Endurance Training
Mesquita, P. H. C.; Godwin, J. S.; Ruple, B. A.; Sexton, C. L.; McIntosh, M. C.; Mueller, B. J.; Osburn, S. C.; Mobley, C. B.; Libardi, C. A.; Young, K. C.; Gladden, L. B.; Roberts, M. D.; Kavazis, A. N.
10.1101/2023.04.06.535919 — molecular biology — Posted on 2023-04-06
3255 Vibrio aestuarianus Clade A and Clade B isolates are associated with Pacific oyster (Crassostrea gigas) disease outbreaks across Ireland
Coyle, N. M.; O'Tool, C.; Thomas, J. C. L.; Ryder, D.; Feil, E. J.; Geary, M.; Bean, T. P.; Joseph, A. W.; Waine, A.; Cheslett, D.; Verner-Jeffreys, D. W.
10.1101/2023.04.06.535062 — microbiology — Posted on 2023-04-06
3258 Defining the molecular identity and morphology of glia limitans superficialis astrocytes in mouse and human
Hasel, P.; Cooper, M. L.; Marchildon, A. E.; Rufen-Blanchette, U.; Kim, R. D.; Ma, T. C.; Kang, U. J.; Chao, M. V.; Liddelow, S. A.
10.1101/2023.04.06.535893 — neuroscience — Posted on 2023-04-06
3259 Expression of DNA repair genes is modulated during differentiation of olfactory sensory neurons
Rowies, F. T.; Batalha, C. M. P. F.; Nakahara, T. S.; Malnic, B.; de Souza-Pinto, N. C.
10.1101/2023.04.06.535865 — neuroscience — Posted on 2023-04-06
3260 The hepatokine FGL1 regulates hepcidin and iron metabolism during the recovery from hemorrhage-induced anemia in mice
Sardo, U.; Perrier, P.; Cormier, K.; Sotin, M.; Desquesnes, A.; Cannizzo, L.; Ruiz Martinez, M.; Thevenin, J.; Billore, B.; Jung, G.; Abboud, E.; Peyssonnaux, C.; Nemeth, E.; Ginzburg, Y.; Ganz, T.; Kautz, L.
10.1101/2023.04.06.535920 — physiology — Posted on 2023-04-06
3262 Building pangenome graphs
Garrison, E.; Guarracino, A.; Heumos, S.; Villani, F.; Bao, Z.; Tattini, L.; Hagmann, J.; Vorbrugg, S.; Marco-Sola, S.; Kubica, C.; Ashbrook, D. G.; Thorell, K.; Rusholme-Pilcher, R. L.; Liti, G.; Rudbeck, E.; Nahnsen, S.; Yang, Z.; Moses, M. N.; Nobrega, F. L.; Wu, Y.; Chen, H.; de Ligt, J.; Sudmant, P. H.; Soranzo, N.; Colonna, V.; Williams, R. W.; Prins, P.
10.1101/2023.04.05.535718 — bioinformatics — Posted on 2023-04-06
3265 Probing Altered Receptor Specificities of Antigenically Drifting Human H3N2 Viruses by Chemoenzymatic Synthesis, NMR and Modeling
Unione, L.; Ammerlaan, A. N. A.; Bosman, G. P.; Broszeit, F.; van der Woude, R.; Liu, Y.; Ma, S.; Liu, L.; Diercks, T.; Arda, A.; de Vries, R. P.; Boons, G.-J.
10.1101/2023.04.05.535696 — biochemistry — Posted on 2023-04-06
3266 Genomic Changes During the Evolution of the Coxiella Genus Along the Parasitism-Mutualism Continuum.
Santos-Garcia, D.; Morel, O.; Henri, H.; El Filali, A.; Buysse, M.; Noël, V.; McCoy, K. D.; Gottlieb, Y.; Klasson, L.; Zenner, L.; Duron, O.; Vavre, F.
10.1101/2022.10.26.513839 — microbiology — Posted on 2023-04-06
3267 Plasma concentrations of anti-inflammatory cytokine TGF-β are associated with hippocampal structure related to explicit memory performance in older adults
Raschick, M.; Richter, A.; Fischer, L.; Knopf, L.; Schult, A.; Yakupov, R.; Behnisch, G.; Guttek, K.; Düzel, E.; Dunay, I. R.; Seidenbecher, C. I.; Schraven, B.; Reinhold, D.; Schott, B. H.
10.1101/2022.12.21.521442 — neuroscience — Posted on 2023-04-06
3271 The GlycoPaSER prototype as a real-time N-glycopeptide identification tool based on the PaSER parallel computing platform
Armony, G.; Brehmer, S.; Srikumar, T.; Pfennig, L.; Zijlstra, F.; Trede, D.; Kruppa, G.; Lefeber, D.; van Gool, A. J.; Wessels, H. J. C. T.
10.1101/2023.03.09.531912 — bioinformatics — Posted on 2023-04-06
3274 Why the brown ghost chirps at night
Oboti, L.; Pedraja, F.; Ritter, M.; Lohse, M.; Klette, L.; Krahe, R.
10.1101/2022.12.29.522225 — animal behavior and cognition — Posted on 2023-04-06
3277 Genetic diversity and demographic history of the leopard seal: a Southern Ocean top predator
Bender, A. N.; Krause, D. J.; Goebel, M. E.; Hoffman, J. I.; Lewallen, E. A.; Carolina, B.
10.1101/2023.04.05.535769 — genetics — Posted on 2023-04-06
3278 Functional redundancy of WDR31 with GTPase-activating proteins ELMOD and RP2 in regulating IFT trains via BBSome
Cevik, S.; Peng, X.; Beyer, T.; Pir, M. S.; Yenisert, F.; Woerz, F.; Hoffmann, F.; Altunkaynak, B.; Pir, B.; Boldt, K.; Karaman, A.; Cakiroglu, M.; Oner, S. S.; Cao, Y.; Ueffing, M.; Kaplan, O. I.
10.1101/2021.06.10.445528 — genetics — Posted on 2023-04-06
3285 Early consequences of the phospholamban mutation PLN-R14del+/- in a transgenic mouse model
Maniezzi, C.; Eskandr, M.; Florindi, C.; Ferrandi, M.; Barassi, P.; Sacco, E.; Pasquale, V.; Maione, A. S.; Pompilio, G.; Oliveira Nunes Teixeira, V.; de Boer, R. A.; Sillje, H. H. W.; Lodola, F.; Zaza, A.
10.1101/2023.04.05.535536 — physiology — Posted on 2023-04-06
3287 N-linked glycosylation of the M-protein variable region: Glycoproteogenomics reveals a new layer of personalized complexity in multiple myeloma.
Langerhorst, P.; Baerenfaenger, M.; Kulkarni, P.; Nadal, S.; Wijnands, C.; Post, M. A.; Noori, S.; vanDuijn, M. M.; Joosten, I.; Dejoie, T.; van Gool, A. J.; Gloerich, J.; Lefeber, D. J.; Wessels, H. J.; Jacobs, J. F. M.
10.1101/2023.04.05.535540 — cancer biology — Posted on 2023-04-06
3288 NanoMOFs with Encapsulated Photosensitizer: Accumulation in Chlamydia trachomatis Inclusions and Antimicrobial Effects
Qi, X.; Grafskaia, E.; Yu, Z.; Shen, N.; Fedina, E.; Masyutin, A.; Erokhina, M.; Lepoitevin, M.; Lazarev, V.; Zigangirova, N.; Serre, C.; Durymanov, M.
10.1101/2023.04.04.535539 — biophysics — Posted on 2023-04-06
3289 Development of subunit selective substrates for Trichomonas vaginalis proteasome
Fajtova, P.; Hurysz, B.; Miyamoto, Y.; Serafim, M.; Jiang, Z.; Trujillo, D. F.; Liu, L. J.; Somani, U.; Almaliti, J.; Myers, S.; Caffrey, C.; Gerwick, W. H.; Kirk, C. J.; Boura, E.; Eckmann, L.; O'Donoghue, A. J.
10.1101/2023.04.05.535794 — biochemistry — Posted on 2023-04-06
3290 Insights into the ISG15 transfer cascade by the UBE1L activating enzyme
Wallace, I.; Baek, K.; Prabu, J. R.; Vollrath, R.; von Gronau, S.; Schulman, B. A.; Swatek, K. N.
10.1101/2023.04.06.535837 — biochemistry — Posted on 2023-04-06
3292 Genetic modifiers of APOBEC-induced mutagenesis
Mertz, T. M.; Rice-Reynolds, E.; Nguyen, L.; Wood, A.; Bray, N.; Mitchell, D.; Lobachev, K.; Roberts, S.
10.1101/2023.04.05.535598 — genomics — Posted on 2023-04-06
3293 Evaluating drought tolerance stability in soybean by theresponse of irrigation change captured from time-seriesmultispectral data
Sakurai, K.; Toda, Y.; Hamazaki, K.; Ohmori, Y.; Yamasaki, Y.; Takahashi, H.; Takanashi, H.; Tsuda, M.; Tsujimoto, H.; Kaga, A.; Nakazono, M.; Fujiwara, T.; Iwata, H.
10.1101/2023.04.05.535659 — genetics — Posted on 2023-04-06
3296 Molecular mechanisms of microbiome modulation by the eukaryotic secondary metabolite azelaic acid
Shibl, A. A.; Ochsenkuhn, M. A.; Mohamed, A. R.; Isaac, A.; Coe, L. S. Y.; Yun, Y.; Skrzypek, G.; Raina, J.-B.; Seymour, J. R.; Afzal, A. J.; Amin, S. A.
10.1101/2022.04.08.487398 — ecology — Posted on 2023-04-06
3298 Patient-derived glioblastoma neurosphere cultures differentially express nicotinic acetylcholine receptors depending on ambient choline
Gondarenko, E. A.; Mazur, D. V.; Masliakova, M.; Riabukha, Y.; Kasheverov, I.; Tsetlin, V.; Kudryavtsev, D. S.; Antipova, N. V.
10.1101/2023.04.06.535046 — molecular biology — Posted on 2023-04-06
3299 Fitness cost associated with cell phenotypic switching drives population diversification dynamics and controllability
Henrion, L.; Martinez Alvarez, J. A.; Vandenbroucke, V.; Delvenne, M.; Telek, S.; Zicler, A.; Grunberger, A.; Frank, D.
10.1101/2023.04.06.535654 — microbiology — Posted on 2023-04-06
3300 Mrs4 loss of function in fungi during adaptation to the cystic fibrosis lung
Murante, D.; Demers, E.; Kurbessoian, T.; Ruzic, M.; Ashare, A.; Stajich, J. E.; Hogan, D. A.
10.1101/2023.04.05.535776 — microbiology — Posted on 2023-04-06
3305 Calcineurin inhibitor nephrotoxicity revisited: perspectives emerging from differential impact on renal compartments
Demirci, H.; Popovic, S.; Dittmayer, C.; Yilmaz, D. E.; El-Shimy, I. A.; Mülleder, M.; Hinze, C.; Mutig, K.; Bachmann, S.
10.1101/2023.04.05.535688 — pathology — Posted on 2023-04-06
3306 An experimental comparison of the Digital Spatial Profiling and Visium spatial transcriptomics technologies for cancer research
Wang, T.; Harvey, K.; Reeves, J.; Roden, D. L.; Bartonicek, N.; Yang, J.; Al-Eryani, G.; Kaczorowski, D.; Chan, C.-L.; Powell, J.; O'Toole, S.; Lim, E.; Swarbrick, A.
10.1101/2023.04.06.535805 — cancer biology — Posted on 2023-04-06
3307 Triggering receptor expressed on myeloid cells 2 (TREM2) regulates phagocytosis in glioblastoma
Peshoff, M. M.; Gupta, P.; Trivedi, R.; Oberai, S.; Chakrapani, P.; Dang, M.; Milam, N. K.; Maynard, M. E.; Vaillant, B. D.; Huse, J. T.; Wang, L.; Clise-Dwyer, K.; Bhat, K. P.
10.1101/2023.04.05.535792 — cancer biology — Posted on 2023-04-06
3309 MRI-Guided Focused Ultrasound Blood-Brain Barrier Opening Increases Drug Delivery and Efficacy in a Diffuse Midline Glioma Mouse Model
Martinez, P. J.; Nault, G.; Steiner, J.; Wempe, M. F.; Pierce, A.; Brunt, B.; Slade, M.; Mongin, A.; Song, J. J.; Song, K.-H.; Ellens, N.; Serkova, N.; Green, A.; Borden, M. A.
10.1101/2023.04.05.534448 — bioengineering — Posted on 2023-04-06
3312 Differential regulation of Retinoic Acid Metabolism in Fanconi Anemia
Blaize, J.; Noori, B.; Hunter, K.; Henrikson, K.; Atoyan, J.; Ardito, A.; Donovan, F.; Chandrasekharappa, S.; Schindler, D.; Howlett, N. G.
10.1101/2023.04.06.535759 — biochemistry — Posted on 2023-04-06
3316 Multiomics of human aortic endothelial cells reveals cell subtypes with heterogeneous responses to canonical endothelial-to-mesenchymal perturbations
Adelus, M. L.; Ding, J.; Tran, B. T.; Conklin, A. C.; Golebiewski, A. K.; Stolze, L. K.; Whalen, M. B.; Cusanovich, D.; Romanoski, C. E.
10.1101/2023.04.03.535495 — genomics — Posted on 2023-04-06
3317 Enriched zones of embedded ribonucleotides are associated with DNA replication and coding sequences in the human mitochondrial genome
Xu, P.; Yang, T.; Kundnani, D. L.; Sun, M.; Marsili, S.; Gombolay, A. L.; Jeon, Y.; Newnam, G.; Balachander, S.; Bazzani, V.; Baccarani, U.; Park, V. S.; Tao, S.; Lori, A.; Schinazi, R. F.; Kim, B.; Pursell, Z. F.; Tell, G. F.; Vascotto, C.; Storici, F.
10.1101/2023.04.05.535745 — genomics — Posted on 2023-04-06
3318 Cell division can accelerate the loss of a heteroplasmic mitochondrial DNA mutation in a mouse model of mitochondrial disease
Su, T.; Gomes, T. M.; Smith, A. L.; Whitehall, J. C.; Blain, A. P.; Simard, M.-L.; Scholten, L.; Stewart, J. B.; Turnbull, D. M.; Lawless, C.; Greaves, L. C.
10.1101/2023.04.06.535821 — genetics — Posted on 2023-04-06
3319 Arsenite methyltransferase 3 regulates hepatic energy metabolism which dictates the hepatic response to arsenic exposure
Delaney, P. M.; Khan, N. S.; OConnor, M. J.; Ambrosio, E. M.; Garcia-Sabate, A. S.; Teo, J. C. M.; Pergantis, S. A.; Ober, E.; Sadler, K. C.
10.1101/2023.04.05.535637 — genetics — Posted on 2023-04-06
3325 SPATIO-TEMPORAL DYNAMICS OF EARLY SOMITE SEGMENTATION IN THE CHICKEN EMBRYO
Maia-Fernandes, A. C.; Martins-Jesus, A.; Pais-de-Azevedo, T.; Magno, R.; Duarte, I.; Andrade, R. P.
10.1101/2023.04.05.535703 — developmental biology — Posted on 2023-04-06
3326 A cell atlas of the human outflow tract of the heart and its adult derivatives
Leshem, R.; Murtuza Baker, S.; Mallen, J.; Wang, L.; Dark, J.; Bamforth, S.; Bobola, N.
10.1101/2023.04.05.535627 — developmental biology — Posted on 2023-04-06
3331 A fluorescent reporter model for the visualization and characterization of TDC
Fiore, A.; Sala, E.; Laura, C.; Riba, M.; Nelli, M.; Fumagalli, V.; Oberrauch, F.; Mangione, M.; Cristofani, C.; Provero, P.; Iannacone, M.; Kuka, M.
10.1101/2023.04.06.535573 — immunology — Posted on 2023-04-06
3332 Host-cell Interactions of Engineered T cell Micropharmacies
Bourne, C.; Wallisch, P.; Dacek, M.; Gardner, T.; Pierre, S.; Vogt, K.; Corless, B.; Bah, M.; Romero-Pichardo, J.; Charles, A.; Kurtz, K.; Tan, D.; Scheinberg, D. A.
10.1101/2023.04.05.535717 — immunology — Posted on 2023-04-06
3333 Loss of myeloid cannabinoid CB1 receptor confers atheroprotection by reducing macrophage proliferation and immunometabolic reprogramming
Wang, Y.; Li, G.; Chen, B.; Shakir, G.; Volz, M.; van der Vorst, E.; Maas, S.; Li, Z.; Maegdefessel, L.; Hristov, M.; Lacy, M.; Lutz, B.; Weber, C.; Herzig, S.; Guillamat Prats, R.; Steffens, S.
10.1101/2023.04.06.535832 — immunology — Posted on 2023-04-06
3335 Non-Hebbian plasticity produces long-lasting associative memories
Faress, I.; Khalil, V.; Hou, W.-H.; Moreno, A.; Andersen, N.; Fonseca, R.; Piriz, J.; Capogna, M.; Nabavi, S.
10.1101/2023.04.06.535862 — neuroscience — Posted on 2023-04-06
3336 Control of working memory maintenance by theta-gamma phase amplitude coupling of human hippocampal neurons
Daume, J.; Kaminski, J.; Schjetan, A. G. P.; Salimpour, Y.; Khan, U.; Reed, C.; Andersen, W.; Valiante, T. A.; Mamelak, A. N.; Rutishauser, U.
10.1101/2023.04.05.535772 — neuroscience — Posted on 2023-04-06
3338 Spinal motoneurons respond aberrantly to serotonin in a rabbit model of cerebral palsy
Reedich, E. J.; Genry, L. T.; Steele, P. R.; Mena Avila, E.; Dowaliby, L.; Drobyshevsky, A.; Manuel, M.; Quinlan, K. A.
10.1101/2023.04.05.535691 — neuroscience — Posted on 2023-04-06
3339 TREM2 mediates MHCII-associated CD4+ T cell response against gliomas
Zheng, J.; Wang, L.; Zhao, S.; Zhang, W.; Chang, Y.; Dheer, A.; Gao, S.; Xu, S.; Ayasoufi, K.; Al-kharboosh, R.; Xie, M.; Johnson, A. J.; Dong, H.; Wu, L.-J.
10.1101/2023.04.05.535697 — neuroscience — Posted on 2023-04-06
3344 Revealing the Grammar of Small RNA Secretion Using Interpretable Machine Learning
Zirak, B.; Naghipourfar, M.; Saberi, A.; Pouyabahar, D.; Zarezadeh, A.; Fish, L.; Luo, L.; Huh, D.; Sharifi-Zarchi, A.; Goodarzi, H.
10.1101/2023.04.04.535452 — systems biology — Posted on 2023-04-06
3345 Cellular energy regulates mRNA translation and degradation in a codon-specific manner
Tomaz da Silva, P.; Zhang, Y.; Theodorakis, E.; Martens, L. D.; Yepez, V. A.; Pelechano, V.; Gagneur, J.
10.1101/2023.04.06.535836 — systems biology — Posted on 2023-04-06
3348 Biological characterization of an emergent virus infecting vegetables in diversified production systems: physostegia chlorotic mottle virus
Temple, C.; Blouin, A. G.; Boezen, D.; Botermans, M.; Durant, L.; De Jonghe, K.; de Koning, P.; Goedefroit, T.; Minet, L.; Steyer, S.; Verdin, E.; Zwart, M. P.; Massart, S.
10.1101/2023.04.03.535357 — plant biology — Posted on 2023-04-06
3349 Strigolactones optimise plant water usage by modulating vessel formation
Zhao, J.; Shi, D.; Kaeufer, K.; Song, C.; Xu, X.; Luzzietti, L.; Bennett, T.; Kaufmann, K.; Greb, T.
10.1101/2023.04.05.535530 — plant biology — Posted on 2023-04-06
3350 A single amino acid substitution in MdLAZY1A dominantly impairs shoot gravitropism in Malus
Dougherty, L.; Borejsza-Wysocka, E.; Miaule, A.; Wang, P.; Zheng, D.; Jansen, M.; BROWN, S. K.; Pineros, M. A.; Dardick, C. D.; Xu, K.
10.1101/2023.04.05.535771 — plant biology — Posted on 2023-04-06
3353 Untangling the mechanisms of pulmonary hypertension-induced right ventricular stiffening in a large animal model
Kakaletsis, S.; Malinowski, M.; Mathur, M.; Sugerman, G. P.; Luci, J. J.; Snider, C.; Jazwiec, T.; Bersi, M. R.; Timek, T. A.; Rausch, M. K.
10.1101/2023.04.03.535491 — physiology — Posted on 2023-04-06
3355 Decoding the Cure-all Effects of Ginseng
Loo, S.; Kam, A.; Dutta, B.; Zhang, X.; Feng, N.; Sze, S. K.; Liu, C.-F.; Wang, X.; Tam, J. P.
10.1101/2023.04.05.535784 — pharmacology and toxicology — Posted on 2023-04-06
3356 Chromogenic detection of telomere lengths in situ aids the identification of precancerous lesions in the prostate
Ertunc, O.; Smearman, E.; Zheng, Q.; Hicks, J. L.; Brosnan-Cashman, J. A.; Jones, T.; Gomes-Alexandre, C.; Trabzonlu, L.; Meeker, A. K.; De Marzo, A. M.; Heaphy, C. M.
10.1101/2023.04.04.535575 — pathology — Posted on 2023-04-06
3357 Increased response to immune checkpoint inhibitors with dietary methionine restriction
Morehead, L. C.; Garg, S.; Wallis, K. F.; Siegel, E. R.; Tackett, A. J.; Miousse, I. R.
10.1101/2023.04.05.535695 — cancer biology — Posted on 2023-04-06
3360 The super-enhancer landscape reflects molecular subgroups of adrenocortical carcinoma
Gunz, S.; Kerdivel, G.; Meirer, J.; Shapiro, I.; Regazzon, B.; Amrouche, F.; Calmejane, M.-A.; Hamroune, J.; Sigala, S.; Berruti, A.; Bertherat, J.; Assie, G.; Hantel, C.; Boeva, V.
10.1101/2023.04.05.535576 — cancer biology — Posted on 2023-04-06
3361 Therapeutic interventions on human xenografts promote systemic dissemination of oncogenes
Raghuram, G. V.; Pal, K.; Sriram, G.; Khan, A.; Joshi, R.; Jadhav, V.; Shinde, S.; Sheikh, A.; Rane, B.; Kangne, H.; Mittra, I.
10.1101/2023.04.06.535826 — cancer biology — Posted on 2023-04-06
3367 Uncovering and engineering the mechanical properties of the adhesion GPCR ADGRG1 GAIN domain
Dumas, L.; Marfoglia, M.; Yang, B.; Hijazi, M.; Larabi, A.; Lau, K.; Pojer, F.; Nash, M.; BARTH, P.
10.1101/2023.04.05.535724 — biophysics — Posted on 2023-04-06
3369 GENI: a web server to identify gene set enrichments in tumor samples
Hayashi, A.; Ruppo, S.; Heilbrun, E. E.; Mazzoni, C.; Adar, S.; Yassour, M.; Abu Rmaileh, A.; Shaul, Y. D.
10.1101/2023.04.05.535584 — bioinformatics — Posted on 2023-04-06
3375 The ENCODE Uniform Analysis Pipelines
Hitz, B. C.; Lee, J.-W.; Jolanki, O.; Kagda, M. S.; Graham, K.; Sud, P.; Gabdank, I.; Strattan, J. S.; Sloan, C. A.; Dreszer, T.; Rowe, L. D.; Podduturi, N. R.; Malladi, V. S.; Chan, E. T.; Davidson, J. M.; Ho, M.; Miyasato, S.; Simison, M.; Tanaka, F.; Luo, Y.; Whaling, I.; Lin, K.; Jou, J.; Hong, E. L.; Lee, B. T.; Sandstrom, R.; Rynes, E.; Nelson, J.; Nishida, A.; Ingersoll, A.; Buckley, M.; Frerker, M.; Kim, D. S.; Boley, N.; Trout, D.; Dobin, A.; Rahmanian, S.; Wyman, D.; Balderrama-Gutierrez, G.; Reese, F.; Durand, N. C.; Dudchenko, O.; Weisz, D.; Rao, S. S. P.; Blackburn, A.; Gkountarou
10.1101/2023.04.04.535623 — bioinformatics — Posted on 2023-04-06
3377 Simple decoding of behavior from a complicated neural manifold
Perkins, S. M.; Cunningham, J. P.; Wang, Q.; Churchland, M. M.
10.1101/2023.04.05.535396 — bioengineering — Posted on 2023-04-06
3380 Echoes from the last Green Sahara: whole genome analysis of Fulani, a key population to unveil the genetic evolutionary history of Africa
D'Atanasio, E.; Risi, F.; Ravasini, F.; Montinaro, F.; Hajiesmaeil, M.; Bonucci, B.; Pistacchia, L.; Amoako-Sakyi, D.; Bonito, M.; Onidi, S.; Colombo, G.; Semino, O.; Destro Bisol, G.; Anagnostou, P.; Metspalu, M.; Tambets, K.; Trombetta, B.; Cruciani, F.
10.1101/2023.04.06.535569 — genetics — Posted on 2023-04-06
3383 Biogeography and the evolution of acoustic communication in the polyploid North American gray treefrog complex
Booker, W. W.; Lemmon, E. M.; Lemmon, A. R.; Ptacek, M. B.; Hassinger, A. T.; Schul, J.; Gerhardt, H. C.
10.1101/2023.04.03.535469 — evolutionary biology — Posted on 2023-04-06
3384 Neutral Drift and Threshold Selection Promote Phenotypic Variation
Erdogan, A. N.; Dasmeh, P.; Socha, R. D.; Chen, J. Z.; Life, B. E.; Jun, R.; Kiritchkov, L.; Kehila, D.; Serohijos, A. W. R.; Tokuriki, N.
10.1101/2023.04.05.535609 — evolutionary biology — Posted on 2023-04-06
3386 Role of pollen flavonoids in the heather-bumble bee-parasite interactions
Tourbez, C.; Semay, I.; Michel, A.; Michez, D.; Gerbaux, P.; Gekiere, A.; Vanderplanck, M.
10.1101/2023.04.06.535809 — ecology — Posted on 2023-04-06
3394 Spatial analysis of human lung cancer reveals organized immune hubs enriched for stem-like CD8 T cells and associated with immunotherapy response
Chen, J. H.; Nieman, L. T.; Spurrell, M.; Jorgji, V.; Richieri, P. M.; Xu, K. H.; Madhu, R.; Parikh, M.; Zamora, I.; Mehta, A.; Nabel, C. S.; Freeman, S. S.; Pirl, J. D.; Lu, C.; Meador, C. B.; Barth, J.; Sakhi, M.; Tang, A. L.; Sarkizova, S.; Price, C.; Yizhak, K.; Hofree, M.; Shih, A.; Sade-Feldman, M.; Boland, G. M.; Pelka, K.; Aryee, M. J.; Korsunsky, I.; Mino-Kenudson, M.; Gainor, J.; Hacohen, N.
10.1101/2023.04.04.535379 — immunology — Posted on 2023-04-06
3395 Chromatin conformation dynamics during CD4+ T cell activation implicates autoimmune disease-associated genes and regulatory elements
Pahl, M. C.; Sharma, P.; Thomas, R. M.; Thompson, Z.; Mount, Z.; Pippin, J.; Morawski, P. A.; Su, C.; Campbell, D. J.; Grant, S. F.; WELLS, A. D.
10.1101/2023.04.05.535731 — immunology — Posted on 2023-04-06
3396 Prelimbic neuron calcium activity predicts perceived hedonic value across drinking solutions and ethanol dependent states in mice
Rinker, J. A.; Hoffman, M.; Knapp, J.; Wukitsch, T. J.; Kutlu, M. G.; Calipari, E. S.; McMahan, C. S.; Baker, G. H.; Woodward, J. J.; Mulholland, P. J.
10.1101/2023.04.04.535635 — neuroscience — Posted on 2023-04-06
3397 3D architecture and a bi-cellular mechanism of touch detection in mechanosensory corpuscle
Nikolaev, Y. A.; Ziolkowski, L. H.; Pang, S.; Li, W.-P.; Feketa, V. V.; Xu, C. S.; Gracheva, E. O.; Bagriantsev, S. N.
10.1101/2023.04.05.535701 — neuroscience — Posted on 2023-04-06
3399 Typical neural adaptation for familiar images in autistic adolescents
Westner, B. U.; Bosch, E.; Utzerath, C.; Buitelaar, J.; de Lange, F. P.
10.1101/2023.04.05.535670 — neuroscience — Posted on 2023-04-06
3401 Inhibition of microtubule detyrosination by parthenolide facilitates functional CNS axon regeneration
Leibinger, M.; Zeitler, C.; Paulat, M.; Gobrecht, P.; Hilla, A.; Andreadaki, A.; Guthoff, R.; Fischer, D.
10.1101/2023.04.05.535722 — neuroscience — Posted on 2023-04-06
3403 Human motor neurons are rare and can be transcriptomically divided into known subtypes
Gautier, O.; Blum, J. A.; Maksymetz, J.; Chen, D.; Schweingruber, C.; Mei, I.; Hermann, A.; Hackos, D. H.; Hedlund, E.; Ravits, J.; Gitler, A. D.
10.1101/2023.04.05.535689 — neuroscience — Posted on 2023-04-06
3404 Dysfunctional Hippocampal-Prefrontal Connectivity without Neuronal Loss Underlies Psychotic-Like Behaviors Following Early-Life Seizure
Ruggiero, R. N.; Marques, D. B.; Rossignoli, M. T.; De Ross, J. B.; Prizon, T.; Beraldo, I. J. S.; Bueno-Junior, L. S.; Kandratavicius, L.; Peixoto-Santos, J. E.; Aguiar, C. L.; Leite, J. P.
10.1101/2022.12.21.521438 — neuroscience — Posted on 2023-04-06
3408 Both CD8 and CD4 T cells contribute to immunosurveillance preventing the development of neoantigen-expressing autochthonous sarcomas
Himes, J. E.; Wisdom, A. J.; Wang, L.; Shepard, S. J.; Daniel, A. R.; Williams, N.; Luo, L.; Ma, Y.; Mowery, Y. M.; Kirsch, D. G.
10.1101/2023.04.04.535550 — cancer biology — Posted on 2023-04-06
3410 Combination CDC-like kinase inhibition (CLK)/Dual-specificity tyrosine-regulated kinase (DYRK) and taxane therapy in CTNNB1-mutated endometrial cancer
Corr, B. R.; Moroney, M. R.; Woodruff, E. R.; Watson, Z. L.; Jordan, K. R.; Danhorn, T.; Bailey, C.; Wolsky, R. J.; Bitler, B. G.
10.1101/2023.04.04.535570 — cancer biology — Posted on 2023-04-06
3414 Advancing Antibiotic Resistance Classification with Deep Learning Using Protein Sequence and Structure
Qabel, A.; Ennadir, S.; Nikolentzos, G.; Lutzeyer, J. F.; Chatzianastasis, M.; Bostrom, H.; Vazirgiannis, M.
10.1101/2022.10.06.511103 — bioinformatics — Posted on 2023-04-06
3416 Assessment of the normal cell contamination impact on tumour samples analysed with SNP arrays: The signal confusion nightmare.
Poulet, C. B.; Swingland, J.; Botta, V.; Robe, P.; Herens, C.; Rogister, B.; Turkheimer, F. E.; Bours, V.
10.1101/2023.04.04.534870 — bioinformatics — Posted on 2023-04-06
3417 Genomics to Notebook (g2nb): extending the electronic notebook to address the challenges of bioinformatics analysis
Reich, M. M.; Tabor, T.; Liefeld, T.; joshi, j.; Kim, F.; Thorvaldsdottir, H.; Blankenberg, D.; Mesirov, J. P.
10.1101/2023.04.04.535621 — bioinformatics — Posted on 2023-04-06
3422 tauFisher accurately predicts circadian time from a single sample of bulk and single-cell transcriptomic data
Duan, J.; Ngo, M. N.; Karri, S. S.; Tsoi, L. C.; Gudjonsson, J. E.; Shahbaba, B.; Lowengrub, J.; Andersen, B.
10.1101/2023.04.04.535473 — bioinformatics — Posted on 2023-04-06
3423 Implementation considerations for deep learning with diffusion MRI streamline tractography
Cai, L. Y.; Lee, H. H.; Newlin, N. R.; Kim, M. E.; Moyer, D.; Rheault, F.; Schilling, K. G.; Landman, B. A.
10.1101/2023.04.03.535465 — bioengineering — Posted on 2023-04-06
3424 A practical method to improve the efficiency of pollination in maize breeding and genetics research
Schoemaker, D. L.; McFarland, F.; Martinell, B.; Michel, K. J.; Mathews, L.; O'Brien, D.; de Leon, N.; Kaeppler, H. F.; Kaeppler, S. M.
10.1101/2023.04.04.535612 — genetics — Posted on 2023-04-06
3425 Comparative Phylogenomics and Phylotranscriptomics Provide Insights into the Genetic Complexity of Nitrogen Fixing Root Nodule Symbiosis
Zhang, Y.; Fu, Y.; Xian, W.; Li, X.; Feng, Y.; Bu, F.; Shi, Y.; Chen, S.; Velzen, R. v.; Berry, A. M.; Salgado, M. G.; Liu, H.; Yi, T.; Fournier, P.; Alloisio, N.; Pujic, P.; Boubakri, H.; Schranz, M. E.; Delaux, P.-M.; Wong, G. K.-s.; Hocher, V.; Svistoonoff, S.; Gherbi, H.; Wang, E.; Kohlen, W.; Wall, L. G.; Parniske, M.; Pawlowski, K.; Philippe, N.; Doyle, J. J.; Cheng, S.
10.1101/2023.04.03.535273 — evolutionary biology — Posted on 2023-04-06
3427 Site-specific length-biomass relationships of arctic arthropod families are critical for accurate ecological inferences
Versluijs, T. S. L.; Zhemchuzhnikov, M. K.; Kutcherov, D.; Roslin, T.; Schmidt, N. M.; van Gils, J. A.; Reneerkens, J.
10.1101/2023.04.04.534924 — ecology — Posted on 2023-04-06
3429 Identifying the limits where variation in consumer stable isotope values reflect variation in diet
Arnoldi, J.-F.; Bortoluzzi, J. R.; Rowland, H.; Harrod, C.; Parnell, A. C.; Payne, N.; Donohue, I.; Jackson, A. L.
10.1101/2023.04.04.535564 — ecology — Posted on 2023-04-06
3432 Circulating exosomes from Alzheimer's disease suppress VE-cadherin expression and induce barrier dysfunction in recipient brain microvascular endothelial cell
Bei, J.; Miranda-Morales, E. G.; Gan, Q.; Qiu, Y.; Husseinzadeh, S.; Liew, J. Y.; Chang, Q.; Krishnan, B.; Gaitas, A.; Yuan, S.; Felicella, M.; Qiu, W.; Fang, X.; Gong, B.
10.1101/2023.04.03.535441 — neuroscience — Posted on 2023-04-06
3434 Uncursing winner's curse: on-line monitoring of directed evolution convergence
Nemoto, T.; Ocari, T.; Planul, A.; Tekinsoy, M.; Zin, E. A.; Dalkara, D.; Ferrari, U.
10.1101/2023.01.03.522172 — bioinformatics — Posted on 2023-04-06
3435 Widespread readthrough events in plants reveal unprecedented plasticity of stop codons
Zhang, Y.; Li, H.; Shen, Y.; Wang, S.; Tian, L.; Yin, H.; Shi, J.; Xing, A.; Zhang, J.; Ali, U.; Sami, A.; Chen, X.; Gao, C.; Zhao, Y.; Lyu, Y.; Wang, X.; Chen, Y.; Tian, Z.; Wu, S.-B.; Wu, L.
10.1101/2023.03.20.533458 — plant biology — Posted on 2023-04-06
3436 Domestication of different varieties in the cheese-making fungus Geotrichum candidum
Bennetot, B.; Vernadet, J. P.; Perkins, V.; Hautefeuille, S.; Rodriguez de la Vega, R. C.; O'Donnell, S.; Snirc, A.; Grondin, C.; Lessard, M.-H.; Peron, A.-C.; Labrie, S.; Landaud, S.; Giraud, T.; Ropars, J.
10.1101/2022.05.17.492043 — genetics — Posted on 2023-04-06
3444 Hepatocyte Dedifferentiation Profiling In Alcohol-Related Liver Disease Identifies CXCR4 As A Driver Of Cell Reprogramming
Aguilar-Bravo, B.; Arino, S.; Blaya, D.; Pose, E.; Martinez Garcia de la Torre, R. A.; Latasa, M. U.; Martinez-Sanchez, C.; Zanatto, L.; Sererols-Vinas, L.; Cantallops, P.; Affo, S.; Coll, M.; Thillen, X.; Dubuquoy, L.; Avila, M. A.; Argemi, J. M.; Lamas Paz, A.; Nevzorova, Y. A.; Cubero, J.; Bataller, R.; Lozano, J. J.; Gines, P.; Mathurin, P.; Sancho-Bru, P.
10.1101/2023.04.04.535566 — cell biology — Posted on 2023-04-06
3445 RhoB promotes Salmonella survival by regulating autophagy
Kirchenwitz, M.; Halfen, J.; von Peinen, K.; Prettin, S.; Kollasser, J.; Brakebusch, C. H.; Rottner, K.; Steffen, A.; Stradal, T.
10.1101/2023.04.05.535690 — cell biology — Posted on 2023-04-06
3446 Dynein-Powered Cell Locomotion Guides Metastasis of Breast Cancer
Tagay, Y.; Kheirabadi, S.; Ataie, Z.; Singh, R.; Prince, O.; Nguyen, A.; Zhovmer, A. S.; Ma, X.; Sheikhi, A.; Tsygankov, D.; Tabdanov, E. D.
10.1101/2023.04.04.535605 — cell biology — Posted on 2023-04-06
3448 Protein homeostasis imprinting across evolution
Koutsandreas, T.; Felden, B.; Chevet, E.; Chatziioannou, A.
10.1101/2020.07.19.210591 — bioinformatics — Posted on 2023-04-06
3450 Vocal complexity in the long calls of Bornean orangutans
Erb, W. M.; Ross, W.; Kazanecki, H.; Setia, T. M.; Madusudhana, S.; Clink, D. J.
10.1101/2023.04.05.535487 — animal behavior and cognition — Posted on 2023-04-06
3451 A single-cell transcriptional timelapse of mouse embryonic development, from gastrula to pup
Qiu, C.; Martin, B. K.; Welsh, I. C.; Daza, R. M.; Le, T.-M.; Huang, X.; Nichols, E. K.; Taylor, M. L.; Fulton, O.; O'Day, D. R.; Gomes, A. R.; Ilcisin, S.; Srivatsan, S.; Deng, X.; Disteche, C. M.; Noble, W. S.; Hamazaki, N.; Moens, C. B.; Kimelman, D.; Cao, J.; Schier, A. F.; Spielmann, M.; Murray, S. A.; Trapnell, C.; Shendure, J.
10.1101/2023.04.05.535726 — developmental biology — Posted on 2023-04-05
3453 Self-supervised denoising for structured illumination microscopy enables long-term super-resolution live-cell imaging
Chen, X.; Qiao, C.; Jiang, T.; Liu, J.; Meng, Q.; Zeng, Y.; Chen, H.; Zhang, Y.; Li, X.; Zhang, G.; Li, Y.; Qiao, H.; Wu, J.; Tan, S.; Li, D.; Dai, Q.
10.1101/2023.04.05.535684 — cell biology — Posted on 2023-04-05
3454 Quantification of extracellular matrix components in immunolabeled tissue samples
Rebollo, E.; Rubi-Sans, G.; Cler, M.; Valls-Lacalle, L.; Nyga, A.; Perez-Amodio, S.; Mateos-Timoneda, M. A.; Engel, E.
10.1101/2023.04.04.535641 — cell biology — Posted on 2023-04-05
3455 Suppression of ferroptosis by vitamin A or antioxidants is essential for neuronal development
Tschuck, J.; Padmanabhan Nair, V.; Galhoz, A.; Ciceri, G.; Rothenaigner, I.; Tchieu, J.; Tai, H.-M.; Stockwell, B. R.; Studer, L.; Menden, M. P.; Vincendeau, M.; Hadian, K.
10.1101/2023.04.05.535746 — cell biology — Posted on 2023-04-05
3457 The recycling endosome biogenesis machinery coordinates BACE1 endosomal sorting and amyloid-Beta production
Brault, J.-B.; Liu, Z.; Bardin, S.; Ladarre, D.; Fraisier, V.; Tchenio, A.; Lenkei, Z.; Salamero, J.; Delevoye, C.; Goud, B.; Miserey, S.
10.1101/2023.04.05.535676 — cell biology — Posted on 2023-04-06
3458 Therapeutic immunization with a whole cell vaccine reduces pneumococcal nasopharyngeal density, shedding, and middle ear infection in mice
Manning, J.; Manna, S.; Dunne, E. M.; Bongcaron, V.; Pell, C.; Patterson, N. L.; Kuil, S. D.; Dhar, P.; Goldblatt, D.; Mulholland, E. K.; Licciardi, P. V.; Robins-Browne, R. M.; Malley, R.; Wijburg, O.; Satzke, C.
10.1101/2023.04.05.534641 — microbiology — Posted on 2023-04-05
3459 Correlated signatures of social behavior in cerebellum and anterior cingulate cortex
Hur, S. W.; Safaryan, K.; Yang, L.; Blair, H. T.; Masmanidis, S. C.; Mathews, P. J.; Aharoni, D.; Golshani, P.
10.1101/2023.04.05.535750 — neuroscience — Posted on 2023-04-05
3460 Dynamic superresolution by Bayesian nonparametric image processing
Sgouralis, I.; Jalihal, A. P.; Xu, L. W. Q.; Walter, N. G.; Presse, S.
10.1101/2023.04.03.535459 — biophysics — Posted on 2023-04-05
3464 Synthetic microbial sensing and biosynthesis of amaryllidaceae alkaloids
d'Oelsnitz, S.; Diaz, D. J.; Acosta, D. J.; Schechter, M. W.; Minus, M. B.; Howard, J. R.; Do, H.; Loy, J.; Alper, H.; Ellington, A. D.
10.1101/2023.04.05.535710 — synthetic biology — Posted on 2023-04-05
3465 A photoreceptor-based hydrogel with red light-responsive reversible sol-gel transition as transient cellular matrix
Hoerner, M.; Bohnert, R.; Becker, J.; Muehlhaeuser, V.; Haerrer, D.; Wong, T. W.; Meier, M.; Weber, W.
10.1101/2023.04.04.535523 — synthetic biology — Posted on 2023-04-05
3467 Drug discovery for heart failure targeting myosin-binding protein C
Bunch, T. A.; Guhathakurta, P.; Thompson, A.; Lepak, V. C.; Carter, A. L.; Thomas, J. J.; Thomas, D. D. D.; Colson, B. A.
10.1101/2023.04.03.535496 — biophysics — Posted on 2023-04-05
3468 TALLSorts: a T-cell acute lymphoblastic leukaemia subtype classifier using RNA-seq expression data
Gu, A. Z.; Schmidt, B.; Lonsdale, A.; Brown, L. M.; Sadras, T.; Ekert, P. G.; Oshlack, A.
10.1101/2023.04.05.535648 — bioinformatics — Posted on 2023-04-05
3470 Hierarchical TAF1-dependent co-translational assembly of the basal transcription factor TFIID
Bernardini, A.; Mukherjee, P.; Scheer, E.; Kamenova, I.; Antonova, S.; Sanchez, P. K. M.; Yayli, G.; Morlet, B.; Timmers, H. T. M.; Tora, L.
10.1101/2023.04.05.535704 — molecular biology — Posted on 2023-04-05
3471 Methotrimeprazine exerts antiviral and neuroprotective effects in Japanese encephalitis virus infection through activation of adaptive ER stress and autophagy
Prajapat, S. K.; Mishra, L.; Khera, S.; Owusu, S. D.; Ahuja, K.; Sharma, P.; Singh, R.; Mahajan, D.; Banerjee, A.; Motiani, R. K.; Vrati, S.; Kalia, M.
10.1101/2023.04.05.535645 — microbiology — Posted on 2023-04-05
3474 Resolvin D2-GPR18 Signaling on Myeloid Cells Limits Plaque Necrosis
Fredman, G.; Lipscomb, M.; Walis, S.; Marinello, M.; Mena, H. A.; Spite, M.
10.1101/2023.04.03.535493 — immunology — Posted on 2023-04-05
3475 Immune Profiling of Dermatologic Adverse Events from Checkpoint Blockade using Tissue Cyclic Immunofluorescence
Maliga, Z.; Kim, D. Y.; Bui, A.-T. N.; Lin, J.-R.; Dewan, A. K.; Murphy, G. F.; Nirmal, A. J.; Lian, C. G.; Sorger, P. K.; LeBoeuf, N. R.
10.1101/2023.04.03.535435 — immunology — Posted on 2023-04-05
3477 TGF-β induces matrisome pathological alterations and EMT in patient-derived prostate cancer tumoroids
Fernandes, S.; Oliver-De La Cruz, J.; Cassani, M.; Morazzo, S.; Durikova, H.; Caravella, A.; Fiore, P.; Azzato, G.; De Marco, G.; Lauria, A.; Izzi, V.; Bosakova, V.; Fric, J.; Filipensky, P.; Forte, G.
10.1101/2023.04.03.534859 — cancer biology — Posted on 2023-04-05
3478 Secondary Structure Detection Through Direct Nanopore RNA Sequencing
Shaw, A.; Craig, J. M.; Amiri, H.; Kim, J.; Upton, H. E.; Pimentel, S. C.; Huang, J. R.; Marqusee, S.; Gundlach, J. H.; Collins, K.; Bustamante, C. J.
10.1101/2023.04.05.535757 — biophysics — Posted on 2023-04-05
3480 Probing Altered Receptor Specificities of Antigenically Drifting Human H3N2 Viruses by Chemoenzymatic Synthesis, NMR and Modeling
Unione, L.; Ammerlaan, A. N. A.; Bosman, G. P.; Broszeit, F.; van der Woude, R.; Liu, Y.; Ma, S.; Liu, L.; Diercks, T.; Arda, A.; de Vries, R. P.; Boons, G.-J.
10.1101/2023.04.05.535696 — biochemistry — Posted on 2023-04-05
3483 Extended regulation interface coupled to the allosteric network and disease mutations in the PP2A-B56δ holoenzyme
Wu, C.-G.; Balakrishnan, V. K.; Parihar, P. S.; Konovolov, K.; Chen, Y.-C.; Merrill, R. A.; Wei, H.; Carragher, B.; Sundaresan, R.; Cui, Q.; Wadzinski, B. E.; Swingle, M. R.; Musiyenko, A.; Honkanen, R.; Chung, W. K.; Suzuki, A.; Strack, S.; Huang, X.; Xing, Y.
10.1101/2023.03.09.530109 — biochemistry — Posted on 2023-04-05
3484 Whole-genome sequencing confirms multiple species of Galapagos giant tortoises
Gaughran, S. J.; Gray, R.; Jones, M.; Fusco, N.; Ochoa, A.; Miller, J. M.; Poulakakis, N.; de Queiroz, K.; Caccone, A.; Jensen, E. L.
10.1101/2023.04.05.535692 — evolutionary biology — Posted on 2023-04-05
3488 Functional characterization of five triterpene synthases through De-novo assembly and transcriptome analysis of Euphorbia grantii and Euphorbia tirucalli
Kumar, A.; Mulge, D. S.; Thakar, K. J.; Pandreka, A.; Warhekar, A. D.; Ramkumar, S.; Sharma, P.; Upadrasta, S.; Shanmugam, D.; Thulasiram, H.
10.1101/2023.04.05.535548 — molecular biology — Posted on 2023-04-05
3489 Safe delivery of AAV vectors to the liver of small weaned pigs by ultrasound guided percutaneous transhepatic portal vein injection
Rothgangl, T.; Hruzova, M.; Gnannt, R.; Aeberhard, N.; Kissling, L.; Grisch, H. M.; Klassa, S.; Rimann, N.; Marquart, K. K.; Ioannidi, E.; Wolf, A.; Kupatt, C.; Sidler, X.; Haeberle, J.; Schwank, G.; Thony, B.
10.1101/2023.04.05.535660 — molecular biology — Posted on 2023-04-05
3490 Characterization of methionine dependence in melanoma cells
Garg, S.; Morehead, L. C.; Bird, J. T.; Graw, S.; Gies, A.; Storey, A. J.; Tackett, A. J.; Edmondson, R. D.; Mackintosh, S. G.; Byrum, S. D.; Miousse, I. R.
10.1101/2023.04.05.535723 — molecular biology — Posted on 2023-04-05
3492 The purinergic receptor P2X7 and the NLRP3 inflammasome are druggable host factors required for SARS-CoV-2 infection
Lecuyer, D.; Nardacci, R.; Tannous, D.; Gutierrez-Mateyron, E.; Deva-Nathan, A.; Subra, F.; Di Primio, C.; Quaranta, P.; Petit, V.; Richetta, C.; Mostefa-Kara, A.; Del Nonno, F.; Falasca, L.; Marlin, R.; Maisonnasse, P.; Delahousse, J.; Pascaud, J.; Deprez, E.; Naigeon, M.; Chaput, N.; Paci, A.; Saada, V.; Ghez, D.; Mariette, X.; Costa, M.; Pistello, M.; Allouch, A.; Delelis, O.; Piacentini, M.; Le Grand, R.; Perfettini, J.-L.
10.1101/2023.04.05.531513 — microbiology — Posted on 2023-04-05
3496 SARS-CoV-2 Spike Protein Accumulation in the Skull-Meninges-Brain Axis: Potential Implications for Long-Term Neurological Complications in post-COVID-19
Rong, Z.; Mai, H.; Kapoor, S.; Puelles, V.; Czogalla, J.; Schaedler, J.; Vering, J.; Delbridge, C.; Steinke, H.; Frenzel, H.; Schmidt, K.; Caliskan, O. S.; Wettengel, J. M.; Cherif, F.; Ali, M.; Kolabas, Z. I.; Ulukaya, S.; Horvath, I.; Zhao, S.; Krahmer, N.; Tahirovic, S.; Yildirim, A. O.; Huber, T.; Ondruschka, B.; Bechmann, I.; Ebert, G.; Protzer, U.; Bhatia, H. S.; Hellal, F.; Erturk, A.
10.1101/2023.04.04.535604 — neuroscience — Posted on 2023-04-05
3497 Automated tumor immunophenotyping predicts clinical benefit from anti-PD-L1 immunotherapy
Li, X.; Eastham, J.; Giltnane, J. M.; Zou, W.; Zijlstra, A.; Tabatsky, E.; Banchereau, R.; Chang, C.-W.; Nabet, B.; Patil, N.; Molinero, L.; Chui, S.; Peterson, M.; Lau, S.; Rangell, L.; Waumans, Y.; Kockx, M.; Orlova, D.; Koeppen, H.
10.1101/2023.04.03.535467 — pathology — Posted on 2023-04-05
3498 In vitro lymph node-mimicking 3D model displays long-term T cell-dependent CLL proliferation and survival
Haselager, M. V.; Van Driel, B.; Perelear, E.; De Rooij, D.; Lashgari, D.; Loos, R.; Kater, A.; Moerland, P.; Eldering, E.
10.1101/2023.04.03.535388 — cancer biology — Posted on 2023-04-05
3501 Melanin enhances metastatic melanoma colonization by inhibiting ferroptosis
Groenewoud, A.; Zhou, G.; Gelmi, M. C.; Yin, J.; Lamers, G. E. M.; van Doorn, R.; Verdijk, R. M.; Jager, M. J.; Engel, F. B.; Snaar, E. B.
10.1101/2023.04.03.535376 — cancer biology — Posted on 2023-04-05
3503 Conditional Generative Learning for Medical Image Imputation
Raad, R.; Ray, D.; Varghese, B.; Hwang, D.; Gill, I.; Duddalwar, V.; Oberai, A. A.
10.1101/2023.04.03.535422 — cancer biology — Posted on 2023-04-05
3507 Cell Painting-based bioactivity prediction boosts high-throughput screening hit-rates and compound diversity
Fredin Haslum, J.; Lardeau, C.-H.; Karlsson, J.; Turkki, R.; Leuchowius, K.-J.; Smith, K.; Mullers, E.
10.1101/2023.04.03.535328 — bioinformatics — Posted on 2023-04-05
3510 Detecting Anomalous Proteins Using Deep Representations
Michael-Pitschaze, T.; Cohen, N.; Ofer, D.; Hoshen, Y.; Linial, M.
10.1101/2023.04.03.535457 — bioinformatics — Posted on 2023-04-05
3512 Chromosome-scale genome assembly of the African spiny mouse (Acomys cahirinus)
Nguyen, E. D.; Nikoonejad Fard, V.; Kim, B.; Collins, S.; Galey, M.; Nelson, B. R.; Wakenight, P.; Gable, S. M.; McKenna, A.; Bammler, T. K.; MacDonald, J.; Okamura, D. M.; Shendure, J.; Beier, D. R.; Marino Ramirez, J.; Majesky, M. W.; Millen, K. J.; Tollis, M.; Miller, D. E.
10.1101/2023.04.03.535372 — genomics — Posted on 2023-04-05
3515 Fatty acid amide hydrolase drives luminal cell differentiation in the adult mammary gland
Tundidor, I.; Seijo-Vila, M.; Blasco-Benito, S.; Rubert-Hernandez, M.; Moreno-Bueno, G.; Bindila, L.; Guzman, M.; Sanchez-Garcia, C.; Perez-Gomez, E.
10.1101/2023.04.03.535417 — developmental biology — Posted on 2023-04-05
3516 Acute irradiation causes persistently altered heterogeneity among medullary thymic epithelial cells
Horie, K.; Miyauchi, M.; Ishikawa, T.; Hayama, M.; Maruyama, Y.; Miyao, T.; Murata, S.; Akiyama, N.; Akiyama, T.
10.1101/2023.04.03.535248 — immunology — Posted on 2023-04-05
3518 ALDH2 dysfunction accelerates ESCC pathogenesis
Flashner, S.; Shimonosono, M.; Matsuura, N.; Ohashi, S.; Klein-Szanto, A. J.; Diehl, J. A.; Chen, C.-H.; Nakagawa, H.
10.1101/2023.04.03.534985 — cancer biology — Posted on 2023-04-05
3519 Melanoma clonal subline analysis uncovers heterogeneity-driven immunotherapy resistance mechanisms
Gruen, C.; Yang, H. H.; Sassano, A.; Wu, E.; Gopalan, V.; Marie, K. L.; Castro, A.; Mehrabadi, F. R.; Wu, C. H.; Church, I.; Needle, G. A.; Smith, C.; Chin, S.; Ebersole, J.; Marcelus, C.; Fon, A.; Liu, H.; Malikic, S.; Sahinalp, C.; Carter, H.; Hannenhalli, S.; Day, C.-P.; Lee, M. P.; Merlino, G.; Perez-Guijarro, E.
10.1101/2023.04.03.535074 — cancer biology — Posted on 2023-04-05
3520 DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation
Mullen, N. J.; Shukla, S. K.; Thakur, R.; Kollala, S. S.; Wang, D.; Chaika, N.; LaBreck, D. A.; Mallareddy, J. R.; Price, D.; Natarajan, A.; Mehla, K.; Sykes, D. B.; Hollingsworth, M. A.; Singh, P. K.
10.1101/2023.04.03.535399 — cancer biology — Posted on 2023-04-05
3521 Mechanism of delayed cell death following simultaneous CRISPR-Cas9 targeting in pancreatic cancers
Teh, S. S. K.; Halper-Stromberg, E.; Morsberger, L.; Bennett, A.; Bowland, K.; Skaist, A.; Cai, F.; Liang, H.; Hruban, R. H.; Roberts, N. J.; Scharpf, R. B.; Zou, Y. S.; Eshleman, J. R.
10.1101/2023.04.03.535384 — cancer biology — Posted on 2023-04-05
3522 Characterization of mitotic phenotypes associated with a MYC synthetic lethal compound
Shi, Q.; Liu, X.; Kalashova, J.; Yang, C.; Li, H.; Long, Y.; Zhang, T.; Zhang, S.; Lv, G.; Huang, J.; Liu, H.; Zhang, J.; Allen, T. D.; Yang, D.
10.1101/2023.04.03.535438 — cancer biology — Posted on 2023-04-05
3523 Spatio-temporal dynamics of the proton motive force on single bacterial cells
Biquet-Bisquert, A.; Carrio, B.; Meyer, N.; Fernandes, T. F. D.; Abkarian, M.; Seduk, F.; Magalon, A.; Nord, A. L.; Pedaci, F.
10.1101/2023.04.03.535353 — biophysics — Posted on 2023-04-05
3525 Coordination of host and endosymbiont gene expression governs endosymbiont growth and elimination in the cereal weevil Sitophilus spp.
Galvao Ferrarini, M.; Vallier, A.; Vincent-Monegat, C.; Dell'Aglio, E.; Gillet, B.; Hughes, S.; Hurtado, O.; Condemine, G.; Zaidman-Remy, A.; Rebollo, R.; Parisot, N.; Heddi, A.
10.1101/2023.04.03.535335 — bioinformatics — Posted on 2023-04-05
3526 DrBERT: A Robust Pre-trained Model in French for Biomedical and Clinical domains
Labrak, Y.; Bazoge, A.; Dufour, R.; Rouvier, M.; Morin, E.; Daille, B.; Gourraud, P.-A.
10.1101/2023.04.03.535368 — bioinformatics — Posted on 2023-04-05
3529 Colorectal cancer detection and treatment with engineered probiotics
Gurbatri, C. R.; Radford, G.; Vrbanac, L.; Coker, C.; Im, J.; Taylor, S. R.; Jang, Y.; Sivan, A.; Rhee, K.; Saleh, A. A.; Chien, T.; Zandkarimi, F.; Lia, I.; Lannagan, T. R.; Wang, T.; Wright, J. A.; Thomas, E.; Kobayashi, H.; Ng, J. Q.; Lawrence, M.; Sammour, T.; Thomas, M.; Lewis, M.; Papanicolas, L.; Perry, J.; Fitzsimmons, T.; Kaazan, P.; Lim, A.; Marker, J.; Ostroff, C.; Rogers, G.; Arpaia, N.; Worthley, D. L.; Woods, S. L.; Danino, T.
10.1101/2023.04.03.535370 — bioengineering — Posted on 2023-04-05
3533 Impact of diet on jejunal microbiota composition during broiler development with special focus on Enterococcus hirae and Enterococcus faecium
Stege, P. B.; Schokker, D.; Harders, F.; Kar, S. K.; Stockhofe, N.; Perricone, V.; Rebel, J. M. J.; de Jong, I.; Bossers, A.
10.1101/2023.04.05.532946 — microbiology — Posted on 2023-04-05
3534 Cell fitness is an omniphenotype
Jacobs, N. C.; Park, J.; Saccone, N. L.; Peterson, T. R.
10.1101/487157 — systems biology — Posted on 2023-04-05
3535 Self-organized intracellular twisters
Dutta, S.; Farhadifar, R.; Lu, W.; kabacaoglu, G.; Blackwell, R.; Stein, D. B.; Lakonishok, M.; Gelfand, V. I.; Shvartsman, S.; Shelley, M.
10.1101/2023.04.04.534476 — biophysics — Posted on 2023-04-05
3537 Tracking Early Mammalian Organogenesis - Prediction and Validation of Differentiation Trajectories at Whole Organism Scale
Imaz Rosshandler, I.; Rode, C.; Guibentif, C.; Ton, M.-L. N.; Dhapola, P.; Keitley, D.; Argelaguet, R.; Calero-Nieto, F. J.; Nichols, J.; Marioni, J. C.; de Bruijn, M.; Gottgens, B.
10.1101/2023.03.17.532833 — developmental biology — Posted on 2023-04-05
3538 Turicibacter strains differentially modify bile acids and host lipids
Lynch, J. B.; Gonzalez, E. L.; Choy, K.; Faull, K. F.; Jewell, T.; Arellano, A.; Liang, J.; Yu, K. B.; Paramo, J.; Hsiao, E. Y.
10.1101/2022.06.27.497673 — microbiology — Posted on 2023-04-05
3540 Complex chemical signals dictate Ah receptor activation through the gut-lung axis
Dong, F.; Murray, I. A.; Annalora, A.; Coslo, D.; Desai, D.; Gowda, K.; Yang, J.; Wang, D.; Koo, I.; Hao, F.; Amin, S. G.; Patterson, A. D.; Marcus, C.; Perdew, G. H.
10.1101/2023.02.22.529529 — biochemistry — Posted on 2023-04-05
3541 Precise Spatial Tuning of Visually Driven Alpha Oscillations in Human Visual Cortex
Yuasa, K.; Groen, I. I. A.; Piantoni, G.; Montenegro, S.; Flinker, A.; Devore, S.; Devinsky, O.; Doyle, W.; Dugan, P.; Friedman, D.; Ramsey, N.; Petridou, N.; Winawer, J.
10.1101/2023.02.11.528137 — neuroscience — Posted on 2023-04-05
3544 Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation
Kolmogorov, M.; Billingsley, K. J.; Mastoras, M.; Meredith, M.; Monlong, J.; Lorig-Roach, R.; Asri, M.; Alvarez Jerez, P.; Malik, L.; Dewan, R.; Reed, X.; Genner, R. M.; Daida, K.; Behera, S.; Shafin, K.; Pesout, T.; Prabakaran, J.; Carnevali, P.; North American Brain Expression Consortium (NABEC), ; Yang, J.; Rhie, A.; Scholz, S. W.; Traynor, B. J.; Miga, K. H.; Jain, M.; Timp, W.; Phillippy, A. M.; Chaisson, M.; Sedlazeck, F. J.; Blauwendraat, C.; Paten, B.
10.1101/2023.01.12.523790 — bioinformatics — Posted on 2023-04-05
3547 Genome instability footprint under rapamycin and hydroxyurea treatments
Li, J.; Stenberg, S.; Yue, J.-X.; Thompson, D.; Mikhalev, E.; Warringer, J.; Liti, G.
10.1101/2023.02.28.530484 — genomics — Posted on 2023-04-05
3549 Rapid detection of DNA and RNA shrimp viruses using CRISPR-based diagnostics
Major, S. R.; Harke, M. J.; Dhar, A. K.; Cruz-Flores, R.; Bodnar, A. G.; Wanamaker, S. A.
10.1101/2022.12.14.520450 — molecular biology — Posted on 2023-04-05
3551 Keypoint-MoSeq: parsing behavior by linking point tracking to pose dynamics
Weinreb, C.; Osman, M. A. M.; Zhang, L.; Lin, S.; Pearl, J.; Annapragada, S.; Conlin, E.; Gillis, W. F.; Jay, M.; Ye, S.; Mathis, A.; Mathis, M. W.; Pereira, T.; Linderman, S. W.; Datta, S. R.
10.1101/2023.03.16.532307 — neuroscience — Posted on 2023-04-05
3552 Distinct roles of Bdnf I and Bdnf IV transcript variant expression in hippocampal neurons
Bach, S. V.; Bauman, A. J.; Hosein, D.; Tuscher, J. J.; Ianov, L.; Greathouse, K. M.; Henderson, B. W.; Herskowitz, J. H.; Martinowich, K.; Day, J. J.
10.1101/2023.04.05.535694 — neuroscience — Posted on 2023-04-05
3554 From breast cancer cell homing to the onset of early bone metastasis: dynamic bone (re)modeling as a driver of metastasis
Young, S. A. E.; Heller, A.-D.; Garske, D. S.; Rummler, M.; Qian, V.; Ellinghaus, A.; Duda, G. N.; Willie, B.; Grueneboom, A.; Cipitria, A.
10.1101/2023.01.24.525352 — bioengineering — Posted on 2023-04-05
3556 Genetic contributions of noncognitive skills to academic development
Malanchini, M.; Allegrini, A. G.; Nivard, M. G.; Biroli, P.; Rimfeld, K.; Cheesman, R.; von Stumm, S.; Demange, P. A.; van Bergen, E.; Grotzinger, A. D.; Raffington, L.; de la Fuente, J.; Pingault, J.-B.; Harden, K. P.; Tucker-Drob, E. M.; Plomin, R.
10.1101/2023.04.03.535380 — genetics — Posted on 2023-04-05
3557 A high-impact COL6A3 mutation alters the response of chondrocytes in neo-cartilage organoids to hyper-physiologic mechanical loading
Bloks, N. G. C.; Harissa, Z.; Adkar, S. S.; Dicks, A.; Hajmousa, G.; Steward, N.; Koning, R. I.; Mulder, A.; de Koning, B. B. R.; Kloppenburg, M.; Coutinho de Almeida, R.; Ramos, Y. F. M.; Guilak, F.; Meulenbelt, I.
10.1101/2022.12.19.520461 — molecular biology — Posted on 2023-04-05
3559 Diverging asymmetry of intrinsic functional organization in autism
Wan, B.; Hong, S.-J.; Bethlehem, R. A. I.; Floris, D. L.; Bernhardt, B. C.; Valk, S. L.
10.1101/2023.04.05.535683 — neuroscience — Posted on 2023-04-05
3560 Cortical gradient perturbation in attention deficit hyperactivity disorder correlates with neurotransmitter-, cell type-specific and chromosome- transcriptomic signatures
Chen, Z.; Xu, T.; Liu, X.; Becker, B.; Li, W.; Miao, K.; Gong, Z.; Zhang, R.; Huo, Z.; Hu, B.; Tang, Y.; Xiao, Z.; Feng, Z.; Chen, J.; Feng, T.
10.1101/2023.04.05.535657 — neuroscience — Posted on 2023-04-05
3561 The genetic legacy of the expansion of Bantu-speaking peoples in Africa
Fortes-Lima, C. A.; Burgarella, C.; Hammaren, R.; Eriksson, A.; Vicente, M.; Jolly, C.; Semo, A.; Gunnink, H.; Pacchiarotti, S.; Mundeke, L.; Matonda, I.; Muluwa, J. K.; Coutros, P.; Nyambe, T. S.; Cikomola, C.; Coetzee, V.; de Castro, M.; Ebbesen, P.; Delanghe, J.; Stoneking, M.; Barham, L.; Lombard, M.; Meyer, A.; Steyn, M.; Malmstrom, H.; Rocha, J.; Soodyall, H.; Pakendorf, B.; Bostoen, K.; Schlebusch, C. M.
10.1101/2023.04.03.535432 — evolutionary biology — Posted on 2023-04-05
3562 Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision
Vromman, M.; Anckaert, J.; Bortoluzzi, S.; Buratin, A.; Chen, C.-Y.; Chu, Q.; Chuang, T.-J.; Dehghannasiri, R.; Dieterich, C.; Dong, X.; Flicek, P.; Gaffo, E.; Gu, W.; He, C.; Hoffmann, S.; Izuogu, O.; Jackson, M. S.; Jakobi, T.; Lai, E. C.; Nuytens, J.; Salzman, J.; Santibanez-Koref, M.; Stadler, P.; Thas, O.; Vanden Eynde, E.; Verniers, K.; Wen, G.; Westholm, J.; Yang, L.; Ye, C.-Y.; Yigit, N.; Yuan, G.-H.; Zhang, J.; Zhao, F.; Vandesompele, J.; Volders, P.-J.
10.1101/2022.12.06.519083 — genomics — Posted on 2023-04-05
3563 Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscle
Voisin, S.; Seale, K.; Jacques, M.; Landen, S.; Harvey, N. R.; Haupt, L. M.; Griffiths, L. R.; Ashton, K. J.; Coffey, V. G.; Thompson, J.-L. M.; Doering, T. M.; Lindholm, M. E.; Walsh, C.; Davison, G.; Irwin, R.; McBride, C.; Hansson, O.; Asplund, O.; Heikkinen, A. E.; Piirila, P.; Pietilainen, K.; Ollikainen, M.; Blocquiaux, S.; Thomis, M.; Coletta, D. K.; Sharples, A. P.; Eynon, N.
10.1101/2022.12.27.522062 — molecular biology — Posted on 2023-04-05
3564 Coregulation of extracellular vesicle production and fluconazole susceptibility in Cryptococcus neoformans
Rizzo, J.; Trottier, A.; Moyrand, F.; Coppee, J.-Y.; Maufrais, C.; Zimbres, A. C. G.; Dang, T. T. V.; Alanio, A.; Desnos-Ollivier, M.; Mouyna, I.; PEHAU-ARNAUDET, G.; Commere, P.-H.; Novault, S.; Ene, I. V.; Nimrichter, L.; Rodrigues, M.; Janbon, G.
10.1101/2023.01.30.526212 — microbiology — Posted on 2023-04-05
3567 A secreted protease-like protein in Zymoseptoria tritici is responsible for avirulence on Stb9 resistance gene in wheat
Amezrou, R.; Audeon, C.; Compain, J.; Gelisse, S.; Ducasse, A.; Saintenac, C.; Lapalu, N.; Louet, C.; Orford, S.; Croll, D.; Amselem, J.; Fillinger, S.; Marcel, T. C.
10.1101/2022.10.31.514577 — plant biology — Posted on 2023-04-05
3569 Assessing bias and robustness of social network metrics using GPS based radio-telemetry data
Kaur, P.; Ciuti, S.; Ossi, F.; Cagnacci, F.; Morellet, N.; Loison, A.; Atmeh, K.; McLoughlin, P.; Reinking, A. K.; Beck, J. L.; Ortega, A. C.; Kauffman, M.; Boyce, M. S.; Salter-Townshend, M.
10.1101/2023.03.30.534779 — animal behavior and cognition — Posted on 2023-04-05
3570 Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer's disease via MFG-E8
Tzioras, M.; Daniels, M. J.; Davies, C.; Baxter, P.; King, D.; McKay, S.; Varga, B. V.; Popovic, K.; Hernandez, M.; Stevenson, A. J.; Barrington, J.; Drinkwater, E.; Borella, J. A.; Holloway, R. K.; Tulloch, J.; Latta, C.; Kandasamy, J.; Sokol, D.; Smith, C.; Miron, V.; Karadottir, R. T.; Hardingham, G.; Henstridge, C. M.; Brennan, P.; McColl, B. W.; Spires-Jones, T. L.
10.1101/795930 — neuroscience — Posted on 2023-04-05
3574 SAM68-regulated ALE selection of Pcdh15 maintains proper synapse development and function
Darwish, M.; Ito, M.; Takase, A.; Ayukawa, N.; Suzuki, S.; Tanaka, M.; Iijima, Y.; Iijima, T.
10.1101/2023.04.04.535307 — neuroscience — Posted on 2023-04-05
3580 Mast fruiting in a large tropical African legume tree provides evidence for the nutrient resource limitation hypothesis
Newbery, D. M.; Schwan, S.; Chuyong, G. B.; Neba, G. A.; Etta, C. E.; Norghauer, J. M.; Worbes, M.
10.1101/2023.04.03.535348 — ecology — Posted on 2023-04-05
3583 A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture
Andradi-Brown, C.; Wichers-Misterek, J. S.; von Thien, H.; Hoeppner, Y. D.; Scholz, J. A. M.; Smedegaard Hansson, H.; Filtenborg Hocke, E.; Gilberger, T. W.; Duffy, M.; Lavstsen, T.; Baum, J.; Otto, T. D.; Cunnington, A. J.; Bachmann, A.
10.1101/2023.03.21.533599 — bioinformatics — Posted on 2023-04-05
3586 Genetic erosion reduces biomass temporal stability in wild fish populations.
Prunier, J. G.; Chevalier, M.; Raffard, A.; Loot, G.; Poulet, N.; Blanchet, S.
10.1101/2019.12.20.884734 — ecology — Posted on 2023-04-05
3588 Extracellular Domains of CAR Reprogram T-Cell Metabolism Without Antigen Stimulation
Lakhani, A.; Chen, X.; Chen, L. C.; Khericha-Gandhi, M.; Chen, Y. Y.; Park, J. O.
10.1101/2023.04.03.533021 — systems biology — Posted on 2023-04-04
3592 Comparing chromatin contact maps at scale: methods and insights
Gunsalus, L. M.; McArthur, E.; Gjoni, K.; Kuang, S.; Pittman, M.; Capra, J. A.; Pollard, K. S.
10.1101/2023.04.04.535480 — bioinformatics — Posted on 2023-04-04
3593 Using macromolecular electron densities to improve the enrichment of active compounds in virtual screening
Ma, W.; Zhang, W.; Le, Y.; Shi, X.; Xu, Q.; Xiao, Y.; Dou, Y.; Wang, X.; Zhou, W.; Peng, W.; Zhang, H.; Huang, B.
10.1101/2023.04.04.535535 — bioinformatics — Posted on 2023-04-04
3594 Phables: from fragmented assemblies to high-quality bacteriophage genomes
Mallawaarachchi, V.; Roach, M. J.; Papudeshi, B.; Giles, S. K.; Grigson, S. R.; Decewicz, P.; Bouras, G.; Hesse, R. D.; Inglis, L. K.; Hutton, A. L.; Dinsdale, E. A.; Edwards, R. A.
10.1101/2023.04.04.535632 — bioinformatics — Posted on 2023-04-04
3595 The complete mitochondrial genome of Spurilla braziliana MacFarland 1909 (Nudibranchia, Aeolidiidae).
Mizobata, H.; Hayashi, K.; Yonezawa, R.; Lanza, A.; Kinoshita, S.; Yoshitake, K.; Asakawa, S.
10.1101/2023.04.04.535430 — genomics — Posted on 2023-04-04
3596 Systematic comparison of high throughput Single-Cell RNA-Seq platforms in complex tissues
Colino Sanguino, Y.; Rodriguez de la Fuente, L.; Gloss, B.; Law, A. M.; Handler, K.; Pajic, M.; Salomon, R.; Gallego Ortega, D.; Valdes Mora, F.
10.1101/2023.04.04.535585 — genomics — Posted on 2023-04-04
3600 A framework for linking hemispheric, full annual cycle prioritizations to local conservation actions for migratory birds
Deluca, W. V.; Seavy, N. E.; Grand, J.; Velasquez-Tibat, J.; Taylor, L.; Bowler, C.; Deppe, J. L.; Knight, E. J.; Lentijo, G. M.; Meehan, T. D.; Michel, N. L.; Saunders, S. P.; Schillerstrom, N.; Smith, M. A.; Witko, C.; Wilsey, C. B.
10.1101/2023.04.03.534556 — ecology — Posted on 2023-04-04
3603 Stricturing Crohn's disease single-cell RNA sequencing reveals fibroblast heterogeneity and intercellular interactions
Mukherjee, P. K.; Nguyen, Q. T.; Li, J.; Zhao, S.; Christensen, S. M.; West, G. A.; Chandra, J.; Gordon, I. O.; Lin, S.; Wang, J.; Mao, R.; Czarnecki, D.; Rayan, C.; Kotak, P.; Plesec, T.; Lal, S.; Fabre, T.; Asano, S.; Bound, K.; Hart, K.; Park, C.; Martinez, R.; Dower, K.; Wynn, T. A.; Hu, S.; Naydenov, N.; Decaris, M.; Turner, S.; Holubar, S. D.; Steele, S. R.; Fiocchi, C.; Ivanov, A. I.; Kravarik, K. M.; Rieder, F.
10.1101/2023.04.03.534781 — immunology — Posted on 2023-04-04
3606 A second unveiling: haplotig masking of the eastern oyster genome improves population-level inference
Puritz, J. B.; Guo, X.; Hare, M. P.; He, Y.; Hillier, L.; Liu, M.; Lotterhos, K. E.; Minx, P.; Modak, T.; Proestou, D.; Rice, E. S.; Tomlison, C.; Warren, W. C.; Witkop, E.; Zhao, H.; Gomez-Chiarri, M.
10.1101/2022.08.29.505626 — genomics — Posted on 2023-04-04
3607 Incorporating environmental heterogeneity and observation effort to predict host distribution and viral spillover from a bat reservoir.
Ribeiro, R.; Matthiopoulos, J.; Lindgren, F.; Tello, C.; Zariquiey, C. M.; Valderrama, W.; Rocke, T. E.; Streicker, D. G.
10.1101/2023.04.04.535562 — ecology — Posted on 2023-04-04
3608 Tristetraprolin promotes survival of mammary progenitor cells by restraining TNFα levels
Stedile, M.; Lara Montero, A.; Garcia Sola, M.; Goddio, M. V.; Beckerman, I.; Bogni, E. S.; Ayre, M.; Naguila, Z.; Coso, O.; Kordon, E. C.
10.1101/2023.04.04.532205 — developmental biology — Posted on 2023-04-04
3611 Targeted IS-element sequencing uncovers transposition dynamics during selective pressure in enterococci
Kirsch, J. M.; Ely, S.; Stellfox, M. E.; Hullahalli, K.; Luong, P.; Palmer, K. L.; Van Tyne, D.; Duerkop, B. A.
10.1101/2022.08.24.505136 — microbiology — Posted on 2023-04-04
3612 Isolation of Actinomyces cricetomyis sp. nov from orocervicofacial abscesses of African giant pouched rats (Cricetomys ansorgei)
Franklin-Guild, R. J.; Labitt, R. N.; McQueary, H. C.; Llanos-Soto, S.; Mitchell, P. K.; Tallmadge, R. L.; Anderson, R. R.; Flint, J. F.; Ophir, A. G.; Thachil, A.; Singh, B.; Goodman, L. B.
10.1101/2023.04.04.535624 — microbiology — Posted on 2023-04-04
3613 Spatial and temporal metagenomics of river compartments reveals viral community dynamics in an urban impacted stream
Rodriguez-Ramos, J. A.; Oliverio, A.; Borton, M. A.; Danczak, R. E.; Mueller, B. M.; Schulz, H.; Ellenbogen, J.; Flynn, R. M.; Daly, R. A.; Schopflin, L.; Shaffer, M.; Goldman, A.; Lewandowski, J.; Stegen, J.; Wrighton, K.
10.1101/2023.04.04.535500 — microbiology — Posted on 2023-04-04
3614 Activation of a Vibrio cholerae CBASS anti-phage system by quorum sensing and folate depletion
Severin, G. B.; Ramliden, M. S.; Ford, K. C.; Van Alst, A. J.; Sanath-Kumar, R.; Decker, K. A.; Hsueh, B. Y.; Yoon, S. H.; Demey, L. M.; O'Hara, B. J.; Rhoades, C. R.; DiRita, V. J.; Ng, W. L.; Waters, C. M.
10.1101/2023.04.04.535582 — microbiology — Posted on 2023-04-04
3615 Activation mechanism and activity of globupain, a thermostable C11 protease from the Arctic Mid-Ocean Ridge hydrothermal system
Royseth, V.; Hurysz, B. M.; Kaczorowska, A.; Dorawa, S.; Fedoy, A.-E.; Arsin, H.; Serafim, M.; Werbowy, O.; Kaczorowski, T.; Stokke, R.; O'Donoghue, A. J.; Steen, I. H.
10.1101/2023.04.04.535519 — microbiology — Posted on 2023-04-04
3617 Activity and diversity of prophages harbored by wheat phyllosphere bacteria
Dougherty, P. E.; Nielsen, T. K.; Riber, L.; Lading, H. H.; Forero-Junco, L. M.; Kot, W.; Raaijmakers, J.; Hansen, L. H.
10.1101/2023.04.04.535595 — microbiology — Posted on 2023-04-04
3618 Three-dimensional chromatin organization promotes genome evolution in a fungal plant pathogen
Torres, D.; Kramer, M.; Tracanna, V.; Lorencini Fiorin, G.; Cook, D.; Seidl, M. F.; Thomma, B.
10.1101/2023.04.04.535574 — microbiology — Posted on 2023-04-04
3619 CDH1 loss defines distinct diffuse-gastric cancer subtype with T cell exhaustion and EZH2 regulon activation
Zou, G.; Huang, Y.; Zhang, S.; Ko, K.-P.; Kim, B. J.; Zhang, J.; Pizzi, M. P.; Jun, S.; Niu, N.; Wang, H.; Song, S.; Ajani, J. A.; Park, J.-I.
10.1101/2023.03.23.533976 — cancer biology — Posted on 2023-04-04
3620 Tamoxifen Response at Single Cell Resolution in Estrogen Receptor-Positive Primary Human Breast Tumors
Kim, H.; Whitman, A. A.; Wisniewska, K.; Kakati, R. T.; Garcia-Recio, S.; Calhoun, B. C.; Franco, H. L.; Perou, C. M.; Spanheimer, P. M.
10.1101/2023.04.01.535159 — cancer biology — Posted on 2023-04-04
3621 Early life exposure to cigarette smoke primes lung function changes and DNA methylation changes at Cyp1a1 upon exposure later in life
Onuzulu, C. D.; Lee, S.; Basu, S.; Comte, J.; Hai, Y.; Hizon, N.; Chadha, S.; Fauni, M. S.; Kahnamoui, S.; Xiang, B.; Halayko, A. J.; Dolinsky, V. W.; Pascoe, C. D.; Jones, M. J.
10.1101/2023.03.03.530858 — genetics — Posted on 2023-04-04
3623 Formulation development and comparability studies with an aluminum-salt adjuvanted SARS-CoV-2 Spike ferritin nanoparticle vaccine antigen produced from two different cell lines
Kumru, O.; Sanyal, M.; Friedland, N.; Hickey, J.; Joshi, R.; Weidenbacher, P.; Do, J.; Cheng, Y.-C.; Kim, P. S.; Joshi, S. B.; Volkin, D. B.
10.1101/2023.04.03.535447 — immunology — Posted on 2023-04-04
3624 Multifunctional requirements for ERK1/2 signaling in the development of ganglionic eminence derived glia and cortical inhibitory neurons
Knowles, S. J.; Holter, M. C.; Li, G.; Bjorklund, G. R.; Rees, K. P.; Martinez-Fuentes, J. S.; Nishimura, K. J.; Afshari, A. E.; Fry, N.; Stafford, A. M.; Vogt, D.; Mangone, M.; Anderson, T.; Newbern, J. M.
10.1101/2022.08.02.502073 — neuroscience — Posted on 2023-04-04
3625 Somatotopic organization among parallel sensory pathways that promote a grooming sequence in Drosophila
Eichler, K.; Hampel, S.; Alejandro, A.; Calle, S.; Santana, A.; Kmecova, L.; Blagburn, J. M.; Hoopfer, E. D.; Seeds, A. M.
10.1101/2023.02.11.528119 — neuroscience — Posted on 2023-04-04
3626 Rapid Audiovisual Integration Guides Predictive Actions
Kreyenmeier, P.; Schroeger, A.; Canal-Bruland, R.; Raab, M.; Spering, M.
10.1101/2022.12.09.519832 — neuroscience — Posted on 2023-04-04
3627 Transsynaptic labeling and transcriptional control of zebrafish neural circuits
Coomer, C.; Naumova, D.; Talay, M.; Zolyomi, B.; Snell, N.; Sorkac, A.; Chanchu, J.-M.; Cheng, J.; Roman, I.; Li, J.; Robson, D.; Barnea, G.; Halpern, M. E.
10.1101/2023.04.03.535421 — neuroscience — Posted on 2023-04-04
3628 ApTOLL, a new therapeutic aptamer for cytoprotection and (re)myelination after Multiple Sclerosis.
Fernandez-Gomez, B.; Marchena, M. A.; Pineiro, D.; Gomez-Martin, P.; Sanchez, E.; Lao, Y.; Valencia, G.; Nocera, S.; Benitez-Fernandez, R.; Castano-Leon, A. M.; Lagares, A.; Hernandez-Jimenez, M.; de Castro, F.
10.1101/2023.01.22.524916 — neuroscience — Posted on 2023-04-04
3629 Pumping Iron: A Multi-omics Analysis of Two Extremophilic Algae Reveals Iron Economy Management
Davidi, L.; Gallaher, S. D.; Ben-David, E.; Purvine, S. O.; Fillmore, T. L.; Nicora, C. D.; Craig, R. J.; Schmollinger, S.; Roje, S.; Blaby-Haas, C. E.; Auber, R. P.; Wisecaver, J.; Merchant, S. S.
10.1101/2023.02.09.527888 — systems biology — Posted on 2023-04-04
3631 Bias in FGFR1 signaling in response to FGF4, FGF8, and FGF9
Karl, K. A.; Hristova, K.; Krejci, P.; Del Piccolo, N.; Light, T.; Roy, T.; Dudeja, P.; Ursachi, V.-C.; Fafilek, B.
10.1101/2022.01.06.475273 — biophysics — Posted on 2023-04-04
3632 Shear Stress Induces a Pro-Inflammatory Phenotype in Human Monocyte-Derived Macrophages
Jui, E.; Kingsley, G.; Pham, H. K.; Singampalli, K.; Birla, R.; Connell, J.; Keswani, S.; Grande-Allen, K. J.
10.1101/2022.12.08.519590 — bioengineering — Posted on 2023-04-04
3633 Differentiation trajectories of the Hydra nervous system reveal transcriptional regulators of neuronal fate
Primack, A. S.; Cazet, J. F.; Morris Little, H.; Mühlbauer, S.; Cox, B. D.; David, C. N.; Farrell, J. A.; Juliano, C.
10.1101/2023.03.15.531610 — developmental biology — Posted on 2023-04-04
3635 Improvements in task performance after practice are associated with scale-free dynamics of brain activity
Kardan, O.; Stier, A. J.; Layden, E. A.; Choe, K. W.; Lyu, M.; Zhang, X.; Beilock, S. L.; Rosenberg, M. D.; Berman, M. G.
10.1101/2020.05.25.114959 — neuroscience — Posted on 2023-04-04
3636 Time as a supervisor: temporal regularity and auditory object learning
DiTullio, R. W.; Parthiban, C.; Piasini, E.; Chaudhari, P.; Balasubramanian, V.; Cohen, Y. E.
10.1101/2022.11.10.515986 — neuroscience — Posted on 2023-04-04
3637 ST3Gal1 synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer
Garnham, R.; Geh, D.; Nelson, R.; Ramon-Gil, E.; Wilson, L.; Schmidt, E. N.; Walker, L.; Adamson, B.; Buskin, A.; Hepburn, A.; Hodgson, K.; Kendall, H.; Frame, F. M.; Maitland, N. J.; Coffey, K.; Robson, C. N.; Elliott, D. J.; Heer, R.; Macauley, M. S.; Munkley, J.; Gaughan, L.; Leslie, J.; Scott, E.
10.1101/2023.04.03.535346 — cancer biology — Posted on 2023-04-04
3639 Computational design of N-linked glycans for high throughput epitope profiling
Greisen, P. J.; Yi, L.; Zhou, R.; Zhou, J.; Johansson, E.; Dong, T.; Liu, H.; Johnsen, L. B.; Lund, S.; Svensson, L. A.; Zhu, H.; Thomas, N.; Yang, Z.; Ostergaard, H.
10.1101/2023.04.04.535514 — bioengineering — Posted on 2023-04-04
3641 Validation of Flavivirus Infectious Clones Carrying Fluorescent Markers for Antiviral Drug Screening and Replication Studies
Cherkashchenko, L.; Gros, N.; Trausch, A.; Neyret, A.; Henaut, M.; Dubois, G.; Villeneuve, M.; Chable-Bessia, C.; Lyonnais, S.; Merits, A.; Muriaux, D. M.
10.1101/2023.04.03.535319 — molecular biology — Posted on 2023-04-04
3642 Functional genomics identifies extension of complex N-glycans as a mechanism to evade lysis by natural killer cells
Zhuang, X.; Woods, J.; Ji, Y.; Scheich, S.; Mo, F.; Voss, M.; Urlaub, H.; Pan, K.-T.; Long, E. O.
10.1101/2023.04.03.535404 — immunology — Posted on 2023-04-04
3644 Harmonized diffusion MRI data and white matter measures from the baseline Adolescent Brain Cognitive Development (ABCD) study
Cetin-Karayumak, S.; Zhang, F.; Billah, T.; Zekelman, L.; Makris, N.; Pieper, S.; O'Donnell, L. J.; Rathi, Y.
10.1101/2023.04.04.535587 — neuroscience — Posted on 2023-04-04
3647 Passive exposure to task-relevant stimuli enhances categorization learning
Schmid, C.; Haziq, M.; Baese-Berk, M. M.; Murray, J. M.; Jaramillo, S.
10.1101/2023.04.04.535463 — neuroscience — Posted on 2023-04-04
3653 Objective assessment of visual attention in toddlerhood
Braithwaite, E.; Kyriakopoulou, V.; Mason, L.; Davidson, A.; Nora, T.; Harper, N.; Earl, M.; Datoo-Partridge, S.; Young, A.; Chew, A.; Falconer, S.; Hajnal, J. V.; Johnson, M. H.; Nosarti, C.; Edwards, D.; Jones, E. J.
10.1101/2023.04.04.534573 — neuroscience — Posted on 2023-04-04
3654 A single base pair duplication in SLC33A1 gene causes fetal losses and neonatal lethality in Manech Tete Rousse dairy sheep
Ben Braiek, M.; Szymczak, S.; Andre, C.; Bardou, P.; Fidelle, F.; Granado-Tajada, I.; Plisson-Petit, F.; Sarry, J.; Woloszyn, F.; Moreno-Romieux, C.; Fabre, S.
10.1101/2023.03.13.532360 — genomics — Posted on 2023-04-04
3657 Acute kidney injury-induced circulating TNFR1/2 elevations correlate with persistent kidney injury and progression to fibrosis
Arthanarisami, A.; Komaru, Y.; Katsouridi, C.; Schumacher, J.; Verges, D. K.; Ning, L.; Abdelmageed, M. M.; Herrlich, A.; Kefaloyianni, E.
10.1101/2023.04.03.534558 — physiology — Posted on 2023-04-04
3658 Chromosomal instability can favor macrophage-mediated immune response and induce a broad, vaccination-like anti-tumor IgG response
Hayes, B. H.; Wang, M.; Zhu, H.; Phan, S. H.; Andrechak, J. C.; Chang, A. H.; Dooling, L. J.; Tobin, M. P.; Marchena, T.; Discher, D.
10.1101/2023.04.02.535275 — cancer biology — Posted on 2023-04-04
3660 A mixed mechano-olfactory code for sniff-invariant odor representations
A. Dehaqani, A.; Michelon, F.; Petrucco, L.; Patella, P.; Piasini, E.; Iurilli, G.
10.1101/2023.04.04.535405 — neuroscience — Posted on 2023-04-04
3662 SEQUENCE VS. STRUCTURE: DELVING DEEP INTO DATA DRIVEN PROTEIN FUNCTION PREDICTION
Tian, X.; Wang, Z.; Yang, K. K.; Su, J.; Du, H.; Zheng, Q.; Guo, G.; Yang, M.; Yang, F.; Yuan, F.
10.1101/2023.04.02.534383 — bioinformatics — Posted on 2023-04-04
3663 Cross-species regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes
Xiang, G.; He, X.; Giardine, B. M.; Weaver, K. J.; Taylor, D. J.; McCoy, R. C.; Jansen, C.; Keller, C. A.; Wixom, A. Q.; Cockburn, A.; Miller, A.; Qi, Q.; He, Y.; Li, Y.; Lichtenberg, J.; Heuston, E. F.; Anderson, S. M.; Luan, J.; Vermunt, M. W.; Yue, F.; Sauria, M. E. G.; Schatz, M. C.; Taylor, J.; Gottgens, B.; Hughes, J. R.; Higgs, D. R.; Weiss, M. J.; Cheng, Y.; Blobel, G. A.; Bodine, D.; Zhang, Y.; Li, Q.; Mahony, S.; Hardison, R. C.
10.1101/2023.04.02.535219 — genomics — Posted on 2023-04-04
3664 The genomic architecture of a continuous color polymorphism in the European barn owl (Tyto alba)
Cumer, T.; Machado, A. P.; San-Jose, L. M.; Ducrest, A.-L.; Simon, C.; Roulin, A.; Goudet, J.
10.1101/2023.04.03.535036 — genomics — Posted on 2023-04-04
3665 A Rab6 to Rab11 transition is required for dense-core granule and exosome biogenesis in Drosophila secondary cells
Wells, A.; Mendes, C. C.; Castellanos, F.; Mountain, P.; Wright, T.; Wainwright, S. M.; Stefana, M. I.; Harris, A. L.; Goberdhan, D. C. I.; Wilson, C.
10.1101/2023.04.04.535541 — cell biology — Posted on 2023-04-04
3667 Identifying determinants of synaptic specificity by integrating connectomes and transcriptomes
Yoo, J.; Dombrovski, M.; Mirshahidi, P.; Nern, A.; LoCascio, S. A.; Zipursky, S. L.; Kurmangaliyev, Y. Z.
10.1101/2023.04.03.534791 — neuroscience — Posted on 2023-04-04
3672 Dividing out quantification uncertainty allows efficient assessment of differential transcript expression
Baldoni, P. L.; Chen, Y.; Hediyeh-zadeh, S.; Liao, Y.; Dong, X.; Ritchie, M. E.; Shi, W.; Smyth, G. K.
10.1101/2023.04.02.535231 — bioinformatics — Posted on 2023-04-04
3676 Genomics-Driven Discovery of Myxopyromides, a Class of Polyketidic Amides Associated with Predation of Myxococcus sp. SDU36
Niu, L.; Hu, W.-F.; Zhang, W.-J.; Lin, Z.-M. Z.; Wang, J.-J.; Zhu, L.-L.; Hu, J.-Q.; Wang, C.-Y.; Li, R.-J.; Li, Y.-Z.; Wu, C.
10.1101/2023.04.01.535179 — biochemistry — Posted on 2023-04-04
3677 A minimally-invasive method for ancient DNA sampling of Prehistoric bone and antler tools and hunting weapons
Tejero, J.-M.; Cheronet, O.; Gelabert, P.; Zagorc, B.; Alvarez-Fernandez, E.; Averbouh, A.; Bar-Oz, G.; Belfer-Cohen, A.; Bosch, M. D.; Bruck, F.; Cueto, M.; Dockner, M.; Fullola, J. M.; Garate, D.; Giannakoulis, M.; Gonzalez, C.; Jakeli, N.; Mangado, X.; Meshveliani, T.; Neruda, P.; Nigst, P. R.; Simkova, P.; Tapia, J.; Sanchez de la Torre, M.; Schwab, C.; Weber, G.; Pinhasi, R.
10.1101/2023.04.02.535282 — genomics — Posted on 2023-04-04
3678 Single-cell long-read mRNA isoform regulation is pervasive across mammalian brain regions, cell types, and development
Joglekar, A.; Hu, W.; Zhang, B.; Narykov, O.; Diekhans, M.; Balacco, J.; Ndhlovu, L.; Milner, T. A.; Fedrigo, O.; Jarvis, E. D.; Sheynkman, G. M.; Korkin, D.; Ross, M. E.; Tilgner, H. U.
10.1101/2023.04.02.535281 — genetics — Posted on 2023-04-04
3679 Genome size, genetic diversity, and phenotypic variability imply the effect of genetic variation instead of ploidy on trait plasticity in the cross-pollinated tree species ofmulberry
Gnanesh, B. N.; Mondal, R.; Arunakumar, G.; Manojkumar, H.; Singh, P.; Bhavya, M.; Sowbhagya, P.; Burji, S. M.; Mogili, T.; Sivaprasad, V.
10.1101/2023.04.02.535280 — genetics — Posted on 2023-04-04
3684 Microalgae as a novel biofactory for biocompatible and bioactive extracellular vesicles
Adamo, G.; Santonicola, P.; Picciotto, S.; Gargano, P.; Nicosia, A.; Longo, V.; Aloi, N.; Romancino, D. P.; Paterna, A.; Rao, E.; Raccosta, S.; Noto, R.; Salamone, M.; Costa, S.; Alfano, C.; Zampi, G.; Colombo, P.; Wei, M.; Touzet, N.; Manno, M.; Di Schiavi, E.; Bongiovanni, A.
10.1101/2023.04.04.535547 — cell biology — Posted on 2023-04-04
3685 Piezo inhibition prevents and rescues scarring by targeting the adipocyte to fibroblast transition
Griffin, M.; Talbott, H.; Guardino, N.; Guo, J.; Spielman, A.; Chen, K.; Mascharak, S.; Parker, J.; Henn, D.; Liang, N.; King, M.; Cotterell, A.; Bauer-Rowe, K.; Abbas, D.; Deleon, N. M. D.; Fahy, E.; Sivaraj, D.; Downer, M.; Akras, D.; Berry, C.; Cook, J.; Quarto, N.; Klein, O. D.; Lorenz, P.; Gurtner, G.; Januszyk, M.; Wan, D. C.; Longaker, M. T.
10.1101/2023.04.03.535302 — cell biology — Posted on 2023-04-04
3687 IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1beta secretion
Dinarello, A.; May, M.; Amo-Aparicio, J.; Azam, T.; Gaballa, J. M.; Marchetti, C.; Tesoriere, A.; Ghirardo, R.; Redzic, J. S.; Webber, W.; Atif, S. M.; Li, S.; Eisenmesser, E. Z.; de Graaf, D. M.; Dinarello, C. A.
10.1101/2023.04.04.535251 — cell biology — Posted on 2023-04-04
3688 Rapid Quantification of First and Second Phase Insulin Secretion Dynamics using In vitro Platform for Improving Insulin Therapy
Thoduvayil, S.; Weerakkody, J. S.; Topper, M.; Bera, M.; Coleman, J.; Li, X.; Mariappan, M.; Ramakrishnan, S.
10.1101/2023.04.03.535481 — cell biology — Posted on 2023-04-04
3689 Systemic Metabolic and Mitochondrial Defects in Rett Syndrome Models
Zlatic, S. A.; Werner, E.; Surapaneni, V.; Lee, C. E.; Gokhale, A.; Singleton, K.; Duong, D.; Crocker, A.; Gentile, K.; Middleton, F.; Patgiri, A.; Tarquinio, D.; Carpenter, R.; Faundez, V.
10.1101/2023.04.03.535431 — neuroscience — Posted on 2023-04-04
3690 Sex-dependent contributions of ventrolateral orbitofrontal cortex and basolateral amygdala to learning under uncertainty
Aguirre, C. G.; Woo, J. H.; Romero-Sosa, J.-L.; Munier, J. J.; Perez, J.; Goldfarb, M.; Das, K.; Gomez, M.; Ye, T.; Pannu, J.; Evans, K.; O'Neill, P. R.; Spigelman, I.; Soltani, A.; Izquierdo, A.
10.1101/2023.04.03.535471 — neuroscience — Posted on 2023-04-04
3693 Caleosin 1 contributes to seed lipid droplet degradation by interaction with autophagy-related protein ATG8
Miklaszewska, M.; Zienkiewicz, K.; Klugier-Borowska, E.; Rygielski, M.; Feussner, I.; Zienkiewicz, A.
10.1101/2023.04.04.535563 — plant biology — Posted on 2023-04-04
3694 Convergence of resistance and evolutionary responses in Escherichia coli and Salmonella enterica co-inhabiting chicken farms in China
Baker, M.; Zhang, X.; Maciel-Guerra, A.; Babaarslan, K.; Dong, Y.; Wang, W.; Hu, Y.; Renney, D.; Liu, L.; Li, H.; Tong, Z.; Pearcy, N.; Zhang, M.; Geng, Y.; Zhao, L.; Hao, Z.; Chen, J.; Peng, Z.; Li, F.; Dottorini, T.
10.1101/2023.03.22.533846 — genomics — Posted on 2023-04-04
3695 Homozygous haplotype deficiency in Manech Tete Rousse dairy sheep revealed a nonsense variant in MMUT gene affecting newborn lamb viability
Ben Braiek, M.; Moreno-Romieux, C.; Andre, C.; Astruc, J.-M.; Bardou, P.; Bordes, A.; Debat, F.; Fidelle, F.; Granado-Tajada, I.; Hoze, C.; Plisson-Petit, F.; Rivemale, F.; Sarry, J.; Tadi, N.; Woloszyn, F.; Fabre, S.
10.1101/2023.03.10.531894 — genomics — Posted on 2023-04-04
3696 Cas9-targeted Nanopore sequencing rapidly elucidates the transposition preferences and DNA methylation profiles of mobile elements in plants
Merkulov, P.; Gvaramiya, S.; Komakhin, R.; Omarov, M.; Dudnikov, M.; Kocheshkova, A.; Konstantinov, Z.; Soloviev, A.; Karlov, G.; Divashuk, M.; Kirov, I.
10.1101/2021.06.11.448052 — genomics — Posted on 2023-04-04
3699 2'-Fucosyllactose helps butyrate producers outgrow competitors in infant gut simulations
Versluis, D. M.; Schoemaker, R.; Looijesteijn, E.; Geurts, J. M. W.; Merks, R. M. H.
10.1101/2023.03.10.532059 — systems biology — Posted on 2023-04-04
3700 Importance of Leaf Age in Grapevines Under Salt Stress
Lupo, Y.; Prashanth, K.; Lazarovitch, N.; Fait, A.; Rachmilevitch, S.
10.1101/2023.04.02.535264 — plant biology — Posted on 2023-04-04
3706 Disruption of the rice 4-DEOXYOROBANCHOL HYDROXYLASE unravels specific functions of canonical strigolactones
Chen, G.-T. E.; Wang, J. Y.; Votta, C.; Braguy, J.; Jamil, M.; Kirschner, G.; Fiorilli, V.; Berqdar, L.; Balakrishna, A.; Blilou, I.; Lanfranco, L.; Al-Babili, S.
10.1101/2023.04.03.535333 — plant biology — Posted on 2023-04-04
3707 Modification of amyloplast size in wheat endosperm through mutation of PARC6 affects starch granule morphology
Esch, L.; Ngai, Q. Y.; Barclay, J. E.; McNelly, R.; Hayta, S.; Smedley, M.; Smith, A. M.; Seung, D.
10.1101/2023.04.03.535339 — plant biology — Posted on 2023-04-04
3708 The DEAD-box helicase RCF1 plays roles in miRNA biogenesis and RNA splicing in Arabidopsis
Xu, C.; Zhang, Z.; He, J.; Bai, Y.; Liu, L.; Tang, J.; Tang, G.; Chen, X.; Mo, B.
10.1101/2023.04.03.535409 — plant biology — Posted on 2023-04-04
3711 Biological characterization of an emergent virus infecting vegetables in diversified production systems: physostegia chlorotic mottle virus
Temple, C.; Blouin, A. G.; Boezen, D.; Botermans, M.; Durant, L.; De Jonghe, K.; De Koning, P.; Goedefroit, T.; Minet, L.; Steyer, S.; Verdin, E.; Zwart, M. P.; Massart, S.
10.1101/2023.04.03.535357 — plant biology — Posted on 2023-04-04
3712 Self-Healable Spider Dragline Silk Materials
Chen, W.-C.; Wang, R.-C.; Yu, S.-K.; Chen, J.-L.; Kao, Y.-H.; Wang, T.-Y.; Chang, P.-Y.; Sheu, H.-S.; Chen, S. C. C.; Liu, W.-R.; Yang, T.-I.; Wu, H.-C.
10.1101/2023.04.01.535237 — bioengineering — Posted on 2023-04-04
3714 Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes
Yu, K.; Basu, A.; Yau, C.; Wolf, D. M.; Goodarzi, H.; Bandyopadhyay, S.; Korkola, J. E.; Hirst, G. L.; Asare, S.; I-SPY 2 TRIAL, ; Demichele, A.; Hylton, N.; Yee, D.; Esserman, L.; van 't Veer, L.; Sirota, M.
10.1101/2023.03.30.534178 — cell biology — Posted on 2023-04-04
3717 A class of antibodies that overcome a steric barrier to cross-group neutralization of influenza viruses
Simmons, H. C.; Watanabe, A.; Oguin, T. H.; Sempowski, G. D.; Kuraoka, M.; Kelsoe, G. H.; McCarthy, K. R.
10.1101/2023.04.01.535242 — microbiology — Posted on 2023-04-04
3718 Cross-species communication via agr controls phage susceptibility in Staphylococcus aureus
Yang, J.; Bowring, J. Z.; Krusche, J.; Bejder, B. S.; Silva, S. F.; Bojer, M. S.; Grunert, T.; Peschel, A.; Ingmer, H.
10.1101/2023.04.03.535347 — microbiology — Posted on 2023-04-04
3720 Integrated Phenomics and Genomics reveals genetic loci associated with inflorescence growth in Brassica napus
Williams, K.; Hepworth, J.; Nichols, B. S.; Corke, F. M. K.; Woolfenden, H. C.; Paajanen, P.; Steuernagel, B.; Ostergaard, L.; Morris, R. J.; Doonan, J. H.; Wells, R.
10.1101/2023.03.31.535149 — plant biology — Posted on 2023-04-04
3721 MAVISp: Multi-layered Assessment of VarIants by Structure for proteins
Arnaudi, M.; Beltrame, L.; Degn, K.; Utichi, M.; Scrima, S.; Sanchez Izquierdo, P.; Maselli, F.; Krzesinska, K.; Dorcakov, T.; Safer, J.; Meldgard, K.; Bruun Brockhoff, J.; Drud Nielsen, A.; Pettenella, A.; Vinhas, J.; Sackett, P. W.; Cava, C.; Iqbal, S.; Lambrughi, M.; Tiberti, M.; Papaleo, E.
10.1101/2022.10.22.513328 — bioinformatics — Posted on 2023-04-04
3723 Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations
Lauterbur, M. E.; Cavassim, M. I. A.; Gladstein, A. L.; Gower, G.; Pope, N. S.; Tsambos, G.; Adrion, J.; Belsare, S.; Biddanda, A.; Caudill, V.; Cury, J.; Echevarria, I.; Haller, B. C.; Hasan, A. R.; Huang, X.; Iasi, L. N. M.; Noskova, E.; Obsteter, J.; Pavinato, V. A. C.; Pearson, A.; Peede, D.; Perez, M. F.; Rodrigues, M. F.; Smith, C. C. R.; Spence, J. P.; Teterina, A.; Tittes, S.; Unneberg, P.; Vazquez, J. M.; Waples, R. K.; Wohns, A. W.; Wong, Y.; Baumdicker, F.; Cartwright, R. A.; Gorjanc, G.; Gutenkunst, R. N.; Kelleher, J.; Kern, A. D.; Ragsdale, A. P.; Ralph, P. L.; Schrider, D. R.; G
10.1101/2022.10.29.514266 — bioinformatics — Posted on 2023-04-04
3724 Sedimentary DNA can reveal the past population dynamics of a pelagic copepod
Nakane, K.; Liu, X.; Doi, H.; Dur, G.; Kuwae, M.; Ban, S.; Tsugeki, N.
10.1101/2022.09.09.506697 — ecology — Posted on 2023-04-04
3726 Modelling the viral dynamics of the SARS-CoV-2 Delta and Omicron variants in different cell types
McCormack, C. P.; Yan, A. W. C.; Brown, J. C.; Sukhova, K.; Peacock, T. P.; Barclay, W. S.; Dorigatti, I.
10.1101/2023.03.15.529513 — microbiology — Posted on 2023-04-04
3732 Engineering a material-genetic interface as safety switch for embedded therapeutic cells
Jerez-Longres, C.; Gomez-Matos, M.; Becker, J.; Horner, M.; Wieland, F.-G.; Timmer, J.; Weber, W.
10.1101/2023.04.03.535359 — synthetic biology — Posted on 2023-04-03
3733 Directed evolution of piperazic acid incorporation by a nonribosomal peptide synthetase
Stephan, P.; Langley, C.; Winkler, D.; Basquin, J.; Caputi, L.; O'Connor, S. E.; Kries, H.
10.1101/2023.04.03.535426 — synthetic biology — Posted on 2023-04-03
3737 Interrogation of dynamic glucose-enhanced MRI and fluorescence-based imaging reveals a perturbed glymphatic network in Huntington disease
Liu, H.; Chen, L.; Zhang, C.; Liu, C.; Li, Y.; Cheng, L.; Wei, Z.; Zhang, Z.; Lu, H.; van Zijl, P. C. M.; Iliff, J. J.; Xu, J.; Duan, W.
10.1101/2023.04.03.535397 — neuroscience — Posted on 2023-04-03
3738 Effects of Aging on Cortical Representations of Continuous Speech
Karunathilake, I. M. D.; Dunlap, J. L.; Perera, J.; Presacco, A.; Decruy, L.; Anderson, S.; Kuchinsky, S. E.; Simon, J. Z.
10.1101/2022.08.22.504825 — neuroscience — Posted on 2023-04-03
3741 Noncanonical interactions and conformational dynamics in cargo-Pex5-Pex14 ternary complex for peroxisomal import
Sonani, R. R.; Blat, A.; Jemiola-Rzeminska, M. R.; Lipinski, O.; Patel, S. N.; Sood, T.; Dubin, G.
10.1101/2023.04.03.535445 — biochemistry — Posted on 2023-04-03
3744 Identification of a novel MCR-1 variant displaying low level of co-resistance to β-lactam antibiotics that uncovers a potential novel antimicrobial peptide
Liang, L.; Zhong, L.-L.; Wang, L.; Zhou, D.; Li, Y.; Li, J.; Chen, Y.; Liang, W.; Wei, W.; Zhang, C.; Zhao, H.; Lyu, L.; Stoesser, N.; Doi, Y.; Paterson, D. L.; Feng, S.; Tian, G.-B.
10.1101/2023.04.03.535341 — microbiology — Posted on 2023-04-03
3745 The characterisation of antimicrobial resistant Escherichia coli from dairy calves
Mwenifumbo, M.; Cookson, A. L.; Zhao, S.; Fayaz, A.; Benschop, J.; Burgess, S. A.
10.1101/2023.04.03.533045 — microbiology — Posted on 2023-04-03
3748 Endosome dysfunction leads to gain-of-function TLR7 and human lupus
Mishra, H.; Schlack-Leigers, C.; Lim, E. L.; Thieck, O.; Magg, T.; Raedler, J.; Wolf, C.; Klein, C.; Ewers, H.; Lee-Kirsch, M. A.; Meierhofer, D.; Hauck, F.; Majer, O.
10.1101/2023.04.03.535356 — immunology — Posted on 2023-04-03
3750 Deep mutational scanning highlights a new role for cytosolic regions in Hrd1 function
Peterson, B. G.; Hwang, J.; Russ, J. E.; Schroeder, J.; Freddolino, P. L.; Baldridge, R. D.
10.1101/2023.04.03.535444 — biochemistry — Posted on 2023-04-03
3751 Semi-synthetic CoA-alpha-Synuclein Constructs Trap N-terminal Acetyltransferase NatB for Binding Mechanism Studies
Pan, B.; Gardner, S.; Schultz, K.; Perez, R.; Deng, S.; Shimogawa, M.; Sato, K.; Rhoades, E.; Marmorstein, R.; Petersson, E. J.
10.1101/2023.04.03.535351 — biochemistry — Posted on 2023-04-03
3752 Chemo-phosphoproteomic profiling with ATR inhibitors berzosertib and gartisertib uncovers new biomarkers and DNA damage response regulators
Jadav, R. S.; Weiland, F.; Noordermeer, S. M.; Carroll, T.; Gao, Y.; Wang, J.; Zhou, H.; Lamoliatte, F.; Munoz, I.; Toth, R.; Macartney, T.; Brown, F.; Hastie, C. J.; Alabert, C.; van Attikum, H.; Zenke, F.; Masson, J.-Y.; Rouse, J.
10.1101/2023.04.03.535285 — biochemistry — Posted on 2023-04-03
3753 Distributable, Metabolic PET Reporting of Tuberculosis
Khan, R. M. N.; Ahn, Y.-M.; Marriner, G. A.; Via, L. E.; D'Hooge, F.; Lee, S. S.; Yang, N.; Basuli, F.; White, A. G.; Tomko, J. A.; Frye, L. J.; Scanga, C. A.; Weiner, D. M.; Sutphen, M. L.; Schimel, D. M.; Dayao, E.; Piazza, M. K.; Gomez, F.; Dieckmann, W.; Herscovitch, P.; Mason, N. S.; Swenson, R.; Kiesewetter, D. O.; Backus, K. M.; Geng, Y.; Raj, R.; Anthony, D. C.; Flynn, J. L.; Barry, C. E.; Davis, B. G.
10.1101/2023.04.03.535218 — biochemistry — Posted on 2023-04-03
3756 Ribosomal protein RPL39L is an efficiency factor in the cotranslational folding ofproteins with alpha helical domains
Banerjee, A.; Ataman, M.; Smialek, M. J.; Mookherjee, D.; Rabl, J.; Mironov, A.; Mues, L.; Enkler, L.; Coto-Llerena, M.; Schmidt, A.; Boehringer, D.; Piscuoglio, S.; Spang, A.; Mittal, N.; Zavolan, M.
10.1101/2023.04.03.535332 — molecular biology — Posted on 2023-04-03
3763 A dirofilariasis mouse model for heartworm preclinical research
Marriott, A. E.; Dagley, J. L.; Hegde, S.; Steven, A.; Fricks, C.; DiCosty, U.; Mansour, A.; Campbell, E. J.; Wilson, C. M.; Gusovsky, F.; Ward, S. A.; Hong, W. D.; O'Neill, P.; Moorhead, A.; McCall, S.; McCall, J. W.; Taylor, M. J.; Turner, J. D.
10.1101/2023.04.03.535321 — microbiology — Posted on 2023-04-03
3764 Differences in vertical and horizontal transmission dynamics shape plasmid distribution in clinical enterobacteria
Alonso-del Valle, A.; Toribio-Celestino, L.; Quirant, A.; Tardio Pi, C.; DelaFuente, J.; Canton, R.; Rocha, E.; Ubeda, C.; Pena-Miller, R.; San Millan, A.
10.1101/2023.04.03.535338 — microbiology — Posted on 2023-04-03
3767 Bidirectional transcription at the PPP2R2B gene locus in spinocerebellar ataxia type 12
Zhou, C.; Liu, H. B.; Bakhsh, F. J.; Wu, B.; Ying, M.; Margolis, R. L.; Li, P. P.
10.1101/2023.04.02.535298 — neuroscience — Posted on 2023-04-03
3768 The structural basis of mRNA recognition and binding by eukaryotic pseudouridine synthase PUS1
Gruenberg, S.; Doyle, L. A.; Wolf, E. J.; Dai, N.; Correa, I. R.; Yigit, E.; Stoddard, B. L.
10.1101/2021.12.08.471817 — biophysics — Posted on 2023-04-03
3770 Purification of Human β and γ-actin from Budding Yeast
Haarer, B. K.; Pimm, M. L.; deJong, E. P.; Amberg, D.; Henty-Ridilla, J. L.
10.1101/2022.08.17.504301 — biochemistry — Posted on 2023-04-03
3772 Comparative transcriptomics reveals divergent paths of chitinase evolution underlying dietary convergence in ant-eating mammals
Allio, R.; Teullet, S.; Lutgen, D.; Magdeleine, A.; Koual, R.; Tilak, M.-K.; de Thoisy, B.; Emerling, C. A.; Lefebure, T.; Delsuc, F.
10.1101/2022.11.29.518312 — evolutionary biology — Posted on 2023-04-03
3779 Human Surfactant Protein A Alleviates SARS-CoV-2 Infectivity in Human Lung Epithelial Cells
Jacob, I. B.; Gemmiti, A.; Xiong, W.; Reynolds, E.; Nicholas, B.; Thangamani, S.; Jia, H.; Wang, G.
10.1101/2023.04.03.535215 — molecular biology — Posted on 2023-04-03
3780 An atlas of gene regulatory networks for memory CD4+ T cells in youth and old age
Wayman, J. A.; Thomas, A.; Bejjani, A. T.; Katko, A.; Almanan, M.; Godarova, A.; Korinfskaya, S.; Cazares, T. A.; Yukawa, M.; Kottyan, L. C.; Barski, A.; Chougnet, C. A.; Hildeman, D. A.; Miraldi, E. R.
10.1101/2023.03.07.531590 — immunology — Posted on 2023-04-03
3781 Target of selective auditory attention can be robustly followed with MEG
Kurmanaviciute, D.; Kataja, H.; Jas, M.; Valila, A.; Parkkonen, L.
10.1101/588491 — neuroscience — Posted on 2023-04-03
3784 Gut bacteria translocation to the brain after ischaemic stroke occurs via the sympathetic nervous system
Peh, A.; Dinakis, E.; Nakai, M.; Muralitharan, R. R.; Rupasinghe, S.; Wilson, J. L.; Wong, C. H. Y.; Jama, H.; Barker, C. M. O.; Modarresi, M.; Kemp-Harper, B. K.; Zheng, T.; Marques, F. Z.; Broughton, B. R. S.
10.1101/2023.04.03.535309 — neuroscience — Posted on 2023-04-03
3786 Serotonergic Modulation of Spinal Circuitry Restores Motor Function after Chronic Spinal Cord Injury
Walvekar, S.; Robinson, R. B.; Chadwick, H. M.; Burch, R. M.; Ding, H.; Perlmutter, S. I.; Moorjani, S.
10.1101/2022.10.04.510858 — neuroscience — Posted on 2023-04-03
3788 Impaired intracellular Ca2+ signaling contributes to age-related cerebral small vessel disease in Col4a1 mutant mice
Yamasaki, E.; Thakore, P.; Ali, S.; Solano, A. S.; Wang, X.; Gao, X.; Labelle-Dumais, C.; Chaumeil, M. M.; Gould, D. B.; Earley, S.
10.1101/2022.08.24.505186 — pathology — Posted on 2023-04-03
3790 Causal identification of single-cell experimental perturbation effects with CINEMA-OT
Dong, M.; Wang, B.; Wei, J.; Fonseca, A. H. d. O.; Perry, C.; Frey, A.; Ouerghi, F.; Foxman, E. F.; Ishizuka, J. J.; Dhodapkar, R. M.; van Dijk, D.
10.1101/2022.07.31.502173 — bioinformatics — Posted on 2023-04-03
3793 Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a NO-CCL2-CCR2 pathway
Ye, Q.; Jo, J.; Wang, C.-Y.; Oh, H.; Choy, T.; Kim, K.; D'Alessandro, A.; Reshetnyak, Y. K.; Jung, S. Y.; Chen, Z.; Marrelli, S. P.; Lee, H. K.
10.1101/2023.04.03.535167 — neuroscience — Posted on 2023-04-03
3795 Astrocyte-Secreted Neurocan Controls Inhibitory Synapse Formation and Function
Irala, D.; Wang, S.; Sakers, K.; Nagendren, L.; Ulloa-Severino, F. P.; Bindu, D. S.; Eroglu, C.
10.1101/2023.04.03.535448 — neuroscience — Posted on 2023-04-03
3799 Transsynaptic labeling and transcriptional control of zebrafish neural circuits
Coomer, C.; Naumova, D.; Talay, M.; Zolyomi, B.; Snell, N.; Sorkac, A.; Chanchu, J.-M.; Cheng, J.; Roman, I.; Li, J.; Robson, D.; Halpern, M. E.; Barnea, G.
10.1101/2023.04.03.535421 — neuroscience — Posted on 2023-04-03
3800 Analytical solutions for the short-term plasticity
Protachevicz, P. R.; Batista, A. M.; Caldas, I. L.; Baptista, M. d. S.
10.1101/2023.04.03.535315 — neuroscience — Posted on 2023-04-03
3805 Age-associated changes in lineage composition of the enteric nervous system regulate gut health and disease
Kulkarni, S.; Saha, M.; Slosberg, J.; Singh, A.; Nagaraj, S.; Becker, L. S.; Zhang, C.; Bukowski, A.; Wang, Z.; Liu, G.; Leser, J.; Kumar, M.; Bakhshi, S.; Anderson, M. J.; Lewandoski, M.; Vincent, E.; Goff, L.; Pasricha, P. J.
10.1101/2020.08.25.262832 — neuroscience — Posted on 2023-04-03
3806 Multi-resolution deep learning characterizestertiary lymphoid structures in solid tumors
van Rijthoven, M.; Obahor, S.; Pagliarulo, F.; van den Broek, M.; Schraml, P.; Moch, H.; van der Laak, J.; Ciompi, F.; Silina, K.
10.1101/2023.04.03.535381 — pathology — Posted on 2023-04-03
3808 Paradoxical increases in anterior cingulate cortex activity during nitrous oxide-induced analgesia reveal a signature of pain affect
Weinrich, J. A.; Liu, C. D.; Jewell, M. E.; Andolina, C. R.; Bernstein, M. X.; Benitez, J.; Rodriguez-Rosado, S.; Braz, J. M.; Maze, M.; Nemenov, M. I.; Basbaum, A. I.
10.1101/2023.04.03.534475 — neuroscience — Posted on 2023-04-03
3809 Human Connectomes Are Heritable
Chung, J.; Bridgeford, E. W.; Powell, M.; Vogelstein, J. T.
10.1101/2023.04.02.532875 — neuroscience — Posted on 2023-04-03
3810 Experimentally induced active and quiet sleep engage non-overlapping transcriptomes in Drosophila
Anthoney, N.; Tainton-Heap, L.; Luong, H.; Notaras, E.; Zhao, Q.; Perry, T.; Batterham, P.; Shaw, P.; van Swinderen, B.
10.1101/2023.04.03.535331 — neuroscience — Posted on 2023-04-03
3812 A zinc finger transcription factor tunes social behaviors by controlling transposable elements and immune response in prefrontal cortex
Truby, N. L.; Kim, R. K.; Silva, G. M.; Qu, X.; Picone, J. A.; Alemu, R.; Neve, R. L.; Cui, X.; Liu, J.; Hamilton, P. J.
10.1101/2023.04.03.535374 — neuroscience — Posted on 2023-04-03
3813 SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration
Hartmann, J.; Bajaj, T.; Otten, J.; Klengel, C.; Gellner, A.-K.; Junglas, E.; Hafner, K.; Anderzhanova, E. A.; Tang, F.; Missig, G.; Rexrode, L.; Li, K.; Poehlmann, M. L.; Heinz, D. E.; Lardenoije, R.; Dedic, N.; McCullough, K. M.; Prochnicki, T.; Rhomberg, T.; Martinelli, S.; Payton, A.; Robinson, A. C.; Stein, V.; Latz, E.; Carlezon, W. A.; Schmidt, M. V.; Murgatroyd, C.; Berretta, S.; Klengel, T.; Pantazopoulos, H.; Ressler, K. J.; Gassen, N. C.
10.1101/2023.04.03.534570 — neuroscience — Posted on 2023-04-03
3815 Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions
Tai, Y.-H.; Engels, D.; Locatelli, G.; Fecher, C.; Theodorou, D.; Mueller, S. A.; Licht-Mayer, S.; Kreutzfeldt, M.; Wagner, I.; Emmanouilidis, I.; Gkotzamani, S.-N.; Trovo, L.; Kendirli, A.; Aljovic, A.; Breckwoldt, M. O.; Naumann, R.; Bareyre, F. M.; Mahad, D.; Merkler, D.; Lichtenthaler, S. F.; Kerschensteiner, M.; Misgeld, T.
10.1101/2023.04.03.535354 — neuroscience — Posted on 2023-04-03
3818 Stochastic modeling of the dynamics of Salmonella infection of epithelial cells
Hannig, J.; Beygi, A.; Ackermann, J.; Amstein, L.; Welsch, C.; Dikic, I.; Koch, I.
10.1101/2023.04.02.535247 — systems biology — Posted on 2023-04-03
3820 Modulation of SLFN11 induces changes in DNA Damage response
Raynaud, C. M.; Ahmed, E. I.; Jabeen, A.; Sanchez, A.; Sherif, S.; Carneiro-Lobo, T. C.; Awad, A.; Awartani, D.; Naik, A.; Thomas, R.; Decock, J.; Zoppoli, G.; Bedognetti, D.; Hendrickx, W.
10.1101/2023.04.02.535254 — cancer biology — Posted on 2023-04-03
3821 Gelation of Uniform Interfacial Diffusant in Embedded 3D Printing
Shin, S.; Brunel, L. G.; Cai, B.; Kilian, D.; Roth, J. G.; Seymour, A. J.; Heilshorn, S. C.
10.1101/2023.04.02.535250 — bioengineering — Posted on 2023-04-03
3822 Pro-inflammatory macrophages impair skeletal muscle regeneration in ischemic-damaged limbs by inducing precocious differentiation of satellite cells
Southerland, K. W.; Xu, Y.; Peters, D. T.; Wei, X.; Lin, X.; Xiang, Y.; Fei, K.; Olivere, L. A.; Morowitz, J. M.; Otto, J.; Kontos, C. D.; Diao, Y.
10.1101/2023.04.01.535211 — genomics — Posted on 2023-04-03
3824 EGR1 regulates oral epithelial cell responses to Candida albicans via the EGFR- ERK1/2 pathway
Dickenson, R. E.; Pellon, A.; Ponde, N.; Hepworth, O.; Daniels-Gatward, L. F.; Naglik, J. R.; Moyes, D. L.
10.1101/2023.03.31.535186 — immunology — Posted on 2023-04-03
3829 Blocking Interleukin-1β transiently limits left ventricular dilation and modulates cardiac lymphangiogenesis in a mouse pressure-overload model
Heron, C.; Lemarcis, T.; Laguerre, O.; Valet, M.; Michel, J.-B.; Mulder, P.; Tardif San Martin, V.; Brakenhielm, E.
10.1101/2023.04.01.535056 — physiology — Posted on 2023-04-03
3831 Pharmacokinetic considerations for optimizing inhaled spray-dried pyrazinoic acid formulations
Yeshwante, S. B.; Hanafin, P.; Miller, B.; Rank, L.; Murcia, S.; Xander, C.; Annis, A.; Baxter, V.; Anderson, E.; Jermain, B.; Konicki, R.; Schmalstig, A.; Stewart, I.; Braunstein, M.; Hickey, A.; Rao, G. G.
10.1101/2023.04.01.534965 — pharmacology and toxicology — Posted on 2023-04-03
3832 The antipsychotic medications aripiprazole, brexpiprazole and cariprazine are off-target respiratory chain complex I inhibitors
Hardy, R. E.; Chung, I.; Yu, Y.; Loh, S. H. Y.; Morone, N.; Soleilhavoup, C.; Travaglio, M.; Serreli, R.; Panman, L.; Cain, K.; Hirst, J.; Martins, L. M.; MacFarlane, M.; Pryde, K. R.
10.1101/2023.04.02.535223 — pharmacology and toxicology — Posted on 2023-04-03
3833 Tamoxifen Response at Single Cell Resolution in Estrogen Receptor-Positive Primary Human Breast Tumors
Kim, H.; Whitman, A. A.; Wisniewska, K.; Kakati, R. T.; Garcia-Recio, S. M.; Calhoun, B. C.; Franco, H.; perou, c.; Spanheimer, P. M.
10.1101/2023.04.01.535159 — cancer biology — Posted on 2023-04-03
3834 Opto-lipidomics of tissues
Jensen, M.; Liu, S.; Stepula, E.; Martella, D.; Birjandi, A. A.; Farrell-Dillon, K.; Chan, K. L. A.; Parsons, M.; Chiappini, C.; Chapple, S. J.; Mann, G. E.; Vercauteren, T.; Abbate, V.; Bergholt, M. S.
10.1101/2023.04.01.534702 — bioengineering — Posted on 2023-04-03
3835 Spatially selective open loop control of magnetic microrobots for drug delivery
Mirkhani, N.; Christiansen, M. G.; Gwisai, T.; Menghini, S.; Schuerle, S.
10.1101/2023.03.31.535118 — bioengineering — Posted on 2023-04-03
3838 Circular RNAs in the human brain are tailored to neuron identity and neuropsychiatric disease
Dong, X.; Bai, Y.; Liao, Z.; Gritsch, D.; Liu, X.; Wang, T.; Borges-Monroy, R.; Ehrlich, A.; Serano, G. E.; Feany, M. B.; Beach, T. G.; Scherzer, C. R.
10.1101/2023.04.01.535194 — genomics — Posted on 2023-04-03
3839 Slide-tags: scalable, single-nucleus barcoding for multi-modal spatial genomics
Russell, A. J. C.; Weir, J. A.; Nadaf, N. M.; Shabet, M.; Kumar, V.; Kambhampati, S.; Raichur, R.; Marrero, G. J.; Liu, S.; Balderrama, K. S.; Vanderburg, C. R.; Shanmugam, V.; Tian, L.; Wu, C. J.; Yoon, C. H.; Macosko, E. Z.; Chen, F.
10.1101/2023.04.01.535228 — genomics — Posted on 2023-04-03
3848 Seasonal variation in great tit (Parus major) energy requirements: reallocation versus increased demand
Pacioni, C.; Sentis, M.; Hambly, C.; Speakman, J.; Kerimov, A.; Bushuev, A.; Lens, L.; Strubbe, D.
10.1101/2023.04.01.535061 — ecology — Posted on 2023-04-03
3849 A broadly protective CHO cell expressed recombinant spike protein subunit based vaccine (IMT-CVAX) against SARS-CoV-2
Jitender, ; Kumar, B. V.; Singh, S.; Verma, G.; Kumar, R.; Mishra, P. M.; Kumar, S.; Nagaraj, S. K.; Nag, J.; Joy, C. M.; Nikam, B.; Singh, D.; Pooja, ; Kalidas, N.; Singh, S.; Mumtaz, ; Bhardwaj, A. K.; Mankotia, D. S.; Ringe, R. P.; Gupta, N.; Tripathi, S.; Mishra, R. P.
10.1101/2023.04.03.534161 — microbiology — Posted on 2023-04-03
3850 Brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke
Garcia-Bonilla, L.; Shahanoor, Z.; Sciortino, R.; Nazarzoda, O.; Racchumi, G.; Iadecola, C.; Anrather, J.
10.1101/2023.03.31.535150 — immunology — Posted on 2023-04-03
3855 nanoCLAMP potently neutralizes SARS-CoV-2 and protects K18-hACE2 mice from infection
Pagneux, Q.; Garnier, N.; Fabregue, M.; Sharkaoui, S.; Mazzoli, S.; Engelmann, I.; Boukherroub, R.; Strecker, M.; Cruz, E.; Ducos, P.; Zarubica, A.; Suderman, R.; Szunerits, S.
10.1101/2023.04.03.535401 — bioengineering — Posted on 2023-04-03
3856 Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing
Cui, L.; Yang, B.; Xiao, S.; Gao, J.; Baud, A.; Graham, D.; McBride, M.; Dominiczak, A.; Schafer, S.; Lopez Aumatell, R.; Mont, C.; Fernandez Teruel, A.; Hubner, N.; Flint, J.; Mott, R.; Huang, L.
10.1101/2023.03.31.535109 — genetics — Posted on 2023-04-03
3859 Species abundances often conform to 'abundant-centre' patterns depending on dispersal capabilities
Panter, C. T.; Bachman, S.; Baines, O.; Bruelheide, H.; Kambach, S.; Sporbert, M.; Field, R.; Schrodt, F.
10.1101/2023.03.31.535106 — ecology — Posted on 2023-04-03
3860 FSHβ links photoperiodic signalling to seasonal reproduction in Japanese quail
Majumdar, G.; Liddle, T. A.; Stewart, C.; Marshall, C. J.; Bain, M.; Stevenson, T.
10.1101/2023.03.30.534954 — zoology — Posted on 2023-04-03
3863 PRMT1 is a critical dependency in clear cell renal cell carcinoma through its role in post-transcriptional regulation of DNA damage response genes
Walton, J.; Ng, A. S.; Arevalo, K.; Apostoli, A.; Meens, J.; Karamboulas, C.; St-Germain, J.; Prinos, P.; Dmytryshyn, J.; Chen, E.; Arrowsmith, C. H.; Raught, B.; Ailles, L.
10.1101/2023.03.30.534936 — cancer biology — Posted on 2023-04-03
3865 Nanopore Sensors for Enhanced Detection of Nanoparticles
Confederat, S.; Lee, S.; Wang, D.; Soulias, D.; Marcuccio, F.; Peace, T. I.; Edwards, M. A.; Strobbia, P.; Samanta, D.; Walti, C.; Actis, P.
10.1101/2023.03.31.534385 — biophysics — Posted on 2023-04-03
3866 The adaptability of the ion binding site by the Ag(I)/Cu(I) periplasmic chaperone SilF.
Lithgo, R.; Hanzevacki, M.; Harris, G.; Kamps, J.; Holden, E.; Benesch, J. L.; Jager, C.; Croft, A.; Hobman, J.; Orville, A.; Quigley, A.; Carr, S.; Scott, D.
10.1101/2023.03.31.534560 — biophysics — Posted on 2023-04-03
3869 Ongoing introgression of a secondary sexual plumage trait in a stable avian hybrid zone
Long, K. M.; Rivera-Colon, A. G.; Bennett, K. F.; Catchen, J. M.; Braun, M. J.; Brawn, J. D.
10.1101/2023.03.30.535000 — evolutionary biology — Posted on 2023-04-03
3870 When cheating turns into a stabilizing mechanism of mutualistic networks
Duchenne, F.; Aubert, S.; Barreto, E.; Brenes, E.; Maglianesi, M. A.; Santander, T.; Guevara, E. A.; Graham, C. H.
10.1101/2023.03.31.533549 — ecology — Posted on 2023-04-03
3871 Eating an elephant, one bite at a time: predator interactions at carrion bonanzas
Morris, A. W.; Smith, I.; Chakrabarti, S.; Lala, F.; Nyagah, S.; Bump, J.
10.1101/2023.03.31.535158 — ecology — Posted on 2023-04-03
3872 Peptidoglycan from Bacillus anthracis Inhibits Human Macrophage Efferocytosis in Part by Reducing Cell Surface Expression of MERTK and TIM-3
Mytych, J. S.; Pan, Z.; Lopez-Davis, C.; Redinger, N.; Lawrence, C.; Ziegler, J.; Popescu, N.; James, J. A.; Farris, A. D.
10.1101/2023.03.30.535001 — immunology — Posted on 2023-04-03
3873 Heat-inactivated mycobacteria activate the Toll-like receptor 2 and 4 pathways in the zebrafish model of tuberculosis
Ferreras Colino, E.; Contreras, M.; Risalde, M. A.; Sevilla, I.; Delgado, E.; Dominguez, L.; Gortazar, C.; de la Fuente, J.
10.1101/2023.03.31.535083 — immunology — Posted on 2023-04-03
3875 Systems analysis of miR-199a/b-5p and multiple miR-199a/b-5p targets during chondrogenesis
Patel, K.; Barter, M. J.; Soul, J.; Proctor, C. J.; Clark, I. M.; Young, D.; Shanley, D. P.
10.1101/2023.03.31.535081 — systems biology — Posted on 2023-04-03
3877 Sex-specific effect of antenatal Zika virus infection on murine fetal growth, placental nutrient transporters, and nutrient sensor signaling pathways
Pereira-Carvalho, D.; Valim, A. C. C.; Andrade, C. B. V.; Bloise, E.; Dias, A. F.; Nascimento, V. M. O.; da Silveira, F. L. B.; Medeiros, I.; Coelho, S. V. A.; Arruda, L. B.; Todeschini, A. R.; Dias, W. B.; Ortiga-Carvalho, T. M.
10.1101/2023.03.30.534997 — physiology — Posted on 2023-04-03
3881 A comprehensive transcriptional signature in pancreatic ductal adenocarcinoma reveals new insights into the immune and desmoplastic microenvironment
Perez-Diez, I.; Andreu, Z.; Hidalgo, M. R.; Perpina-Clerigues, C.; Fantin, L.; Fernandez-Serra, A.; de la Iglesia-Vaya, M.; Lopez-Guerrero, J. A.; Garcia-Garcia, F.
10.1101/2023.03.31.535058 — cancer biology — Posted on 2023-04-03
3882 Dynamic molecular mechanism of the nuclear pore complex permeability barrier
Kozai, T.; Fernandez-Martinez, J.; van Eeuwen, T.; Gallardo, P.; Kapinos, L. E.; Mazur, A.; Zhang, W.; Tempkin, J.; Delgado-Izquierdo, M.; Raveh, B.; Sali, A.; Chait, B. T.; Veenhoff, L. L.; Rout, M. P.; Lim, R. Y. H.
10.1101/2023.03.31.535055 — biophysics — Posted on 2023-04-03
3883 Cell-derived ECM loaded electrospun Polycaprolactone/Chitosan nanofibrous scaffolds for periodontal regeneration
Santos, M. S.; Cordeiro, R.; Moura, C. S.; Cabral, J. M. S.; Ferreira, F. C.; Silva, J. C.; Carvalho, M. S.
10.1101/2023.03.30.534964 — bioengineering — Posted on 2023-04-03
3884 Magnetically Controlled Cyclic Microscale Deformation of in vitro Cancer Invasion Models
Asgeirsson, D. O.; Mehta, A.; Hesse, N.; Scheeder, A.; Ward, R.; Li, F.; Christiansen, M. G.; De Micheli, A.; Ildiz, E. S.; Aceto, N.; Schuerle, S.
10.1101/2023.03.30.534990 — bioengineering — Posted on 2023-04-03
3886 3D-Printed LEGO(R)-inspired Titanium Scaffolds for Patient-Specific Regenerative Medicine
Lee, S. S.; Du, X.; Smit, T.; Bissacco, E. G.; Seiler, D.; de Wild, M.; Ferguson, S. J.
10.1101/2023.03.30.534953 — bioengineering — Posted on 2023-04-03
3889 Distribution of the invasive Anisandrus maiche (Coleoptera: Scolytinae) in Switzerland, first record in Europe of its ambrosia fungus Ambrosiella cleistominuta, and its new association with Xylosandrus crassiusculus
Ribeiro-Correia, J. P.; Prospero, S.; Beenken, L.; Biedermann, P. H. W.; Blaser, S.; Chittaro, Y.; Frey, D.; Hölling, D.; Kaya, S. O.; Knizek, M.; Mittelstrass, J.; Branco, M.; Ruffner, B.; Sanchez, A.; Brockerhoff, E. G.
10.1101/2023.03.30.534995 — ecology — Posted on 2023-04-03
3891 Uncovering the history of recombination and population structure in western Canadian stripe rust populations through mating-type alleles
Holden, S.; Bakkeren, G.; Hubensky, J.; Bamrah, R.; Abbasi, M.; Qutob, D.; de Graaf, M.-L.; Kim, S. H.; Kutcher, H. R.; McCallum, B.; Randhawa, H. S.; Iqbal, M.; Uloth, K.; Burlakoti, R.; Brar, G. S.
10.1101/2023.03.30.534825 — genomics — Posted on 2023-04-03
3893 TopBP1 utilises a bipartite GINS binding mode to activate the replicative helicase
Day, M.; Tetik, B.; Parlak, M.; Almeida-Hernandez, Y.; Raeschle, M.; Kaschani, F.; Siegert, H.; Marko, A.; Sanchez-Garcia, E.; Kaiser, M.; Barker, I.; Pearl, L. H.; Oliver, A.; Boos, D.
10.1101/2023.03.31.535063 — molecular biology — Posted on 2023-04-03
3895 Widespread readthrough events in plants reveal unprecedented plasticity of stop codons
Wu, L.; Wu, S.-B.; Tian, Z.; Zhang, Y.; Li, H.; Shen, Y.; Wang, S.; Tian, L.; Yin, H.; Shi, J.; Xing, A.; Zhang, J.; Ali, U.; Sami, A.; Chen, X.; Gao, C.; Zhao, Y.; Lyu, Y.; Wang, X.; Chen, Y.
10.1101/2023.03.20.533458 — plant biology — Posted on 2023-04-03
3897 Selection and adaptive introgression guided the complex evolutionary history of the European common bean
Bellucci, E.; Benazzo, A.; Xu, C.; Bitocchi, E.; Rodriguez, M.; Alseekh, S.; Di Vittori, V.; Gioia, T.; Neumann, K.; Cortinovis, G.; Frascarelli, G.; Murube, E.; Trucchi, E.; Nanni, L.; Ariani, A.; Logozzo, G.; Shin, J. H.; Liu, C.; Jiang, L.; Ferreira, J. J.; Campa, A.; Attene, G.; Morrell, P. L.; Bertorelle, G.; Graner, A.; Gepts, P.; Fernie, A. R.; Jackson, S. A.; Papa, R.
10.1101/2022.09.28.509856 — genomics — Posted on 2023-04-03
3899 PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle
Benzarti, M.; Oudin, A.; Viry, E.; Gargiulo, E.; Schmoetten, M.; Neises, L.; Pulido, C.; Lorenz, N. I.; Ronellenfitsch, M. W.; Sumpton, D.; Warmoes, M.; Jaeger, C.; Lesur, A.; Paggetti, J.; Moussay, E.; Niclou, S. P.; Letellier, E.; Meiser, J.
10.1101/2023.01.23.525168 — cancer biology — Posted on 2023-04-03
3901 The negative adipogenesis regulator DLK1 is transcriptionally regulated by TIS7 (IFRD1) and translationally by its orthologue SKMc15 (IFRD2)
Vietor, I.; Cikes, D.; Piironen, K.; Vasakou, T.; Heimdoerfer, D.; Gstir, R.; Erlacher, M. D.; Tancevski, I.; Eller, P.; Demetz, E.; Hess, M.; Kuhn, V.; Degenhart, G.; Rozman, J.; Klingenspor, M.; Hrabe de Angelis, M.; Valovka, T.; Huber, L. A.
10.1101/719922 — cell biology — Posted on 2023-04-03
3905 Unzipped assemblies of polyploid root-knot nematode genomes reveal new kinds of unilateral composite telomeric repeats
Zotta Mota, A. P.; Koutsovoulos, G. D.; Perfus-Barbeoch, L.; Despot-Slade, E.; Labadie, K.; Aury, J.-M.; Robbe-Sermesant, K.; Bailly-Bechet, M.; Belser, C.; Pere, A.; Rancurel, C.; Kozlowski, D. K.; Hassanaly-Goulamhoussen, R.; Da Rocha, M.; Noel, B.; Mestrovic-Radan, N.; Wincker, P.; Danchin, E. G.
10.1101/2023.03.29.534350 — genomics — Posted on 2023-04-03
3906 Proton and alpha radiation-induced mutational profiles in human cells
Delhomme, T. M.; Munteanu, M.; Buonanno, M.; Grilj, V.; Biayna, J.; Supek, F.
10.1101/2022.07.29.501997 — genetics — Posted on 2023-04-03
3909 The unique synaptic circuitry of specialized olfactory glomeruli in Drosophila melanogaster
Gruber, L.; Cantera, R.; Pleijzier, M. W.; Steinert, M.; Pertsch, T.; Hansson, B. S.; Rybak, J.
10.1101/2022.09.30.510181 — neuroscience — Posted on 2023-04-03
3911 Unzipped assemblies of polyploid root-knot nematode genomes reveal new kinds of unilateral complex telomeric repeats
Zotta Mota, A. P.; Koutsovoulos, G. D.; Perfus-Barbeoch, L.; Despot-Slade, E.; Labadie, K.; Aury, J.-M.; Robbe-Sermesant, K.; Bailly-Bechet, M.; Belser, C.; Pere, A.; Rancurel, C.; Kozlowski, D. K.; Hassanaly-Goulamhoussen, R.; Da Rocha, M.; Noel, B.; Mestrovic-Radan, N.; Wincker, P.; Danchin, E. G.
10.1101/2023.03.29.534350 — genomics — Posted on 2023-04-03
3912 Ciliary protein CEP290 regulates focal adhesion via microtubule system in non-ciliated cells
Matsuo, K.; Nakajima, Y.; Shigeta, M.; Kobayashi, D.; Sakaki, S.; Inoue, S.; Takeshita, N.; Ueyama, A.; Nishikawa, K.; Saba, R.; Yokoyama, T.; Yashiro, K.
10.1101/2023.04.02.535304 — cell biology — Posted on 2023-04-03
3913 Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation
Latour, S.; Minet, N.; Boschat, A.-C.; Lane, R.; Laughton, D.; Beer, P.; Asnagli, H.; Soudais, C.; Bourne, T.; Fischer, A.; Martin, E.
10.1101/2023.03.29.534741 — cell biology — Posted on 2023-04-03
3914 ATP13A4 upregulation drives the elevated polyamine transport system in the breast cancer cell line MCF7
van Veen, S.; Kourti, A.; Ausloos, E.; Van Asselberghs, J.; Van den Haute, C.; Baekelandt, V.; Eggermont, J.; Vangheluwe, P.
10.1101/2023.03.31.534207 — cell biology — Posted on 2023-04-03
3915 Novel non hot spot modification in Fks1 of Candida auris confers echinocandin resistance
Kordalewska, M.; Cancino-Prado, G.; Nobrega de Almeida, J.; Brasil Brandao, I.; Tigulini de Souza Peral, R.; Lopes Colombo, A.; Perlin, D. S.
10.1101/2023.03.29.534846 — microbiology — Posted on 2023-04-03
3916 Attractant and repellent induce opposing changes in the chemoreceptor four-helix bundle ligand-binding domain
Guo, L.; Wang, Y.-H.; Cui, R.; Huang, Z.; Hong, Y.; Qian, J.-W.; Ni, B.; Xu, A.-M.; Jiang, C.; Zhulin, I.; Liu, S.-J.; Li, D.-F.
10.1101/2023.03.29.534785 — microbiology — Posted on 2023-04-03
3918 Deletion of arrestin-3 does not alter compulsive morphine-seeking behavior in an oral operant self-administration paradigm
Felth, L.; Gooding, S.; Foxall, R.; Rosa, Z.; Ireton, K.; Sall, I. J.; Gipoor, J.; Gaur, A.; King, M.; Dirks, N.; Whistler, C. A.; Whistler, J. A.
10.1101/2023.03.30.534994 — animal behavior and cognition — Posted on 2023-04-03
3919 Single-cell phenomics reveals behavioural and mechanical heterogeneities underpinning collective migration during mouse anterior patterning
Stower, M.; Zhou, F.; Hathrell, H.; Yeung, J.; Thowfeequ, S.; Godwin, J.; Schneider, F.; Lagerholm, C.; Fritzsche, M.; Thiyagalingam, J.; Lu, X.; Rittscher, J.; Srinivas, S.
10.1101/2023.03.31.534937 — developmental biology — Posted on 2023-04-03
3921 A Trisomy 21 Lung Cell Atlas
Bhattacharya, S.; Cherry, C.; Deutsch, G.; Birth Defects Research Laboratory, ; Glass, I.; Mariani, T.; Al Alam, D.; Danopoulos, S.
10.1101/2023.03.30.534839 — developmental biology — Posted on 2023-04-03
3922 The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms
Bui, D. L. H.; Roach, A.; Li, J.; Bandekar, S. J.; Orput, E.; Raghavan, R.; Arac, D.; Sando, R.
10.1101/2023.04.02.535287 — cell biology — Posted on 2023-04-03
3923 Mitochondrial GTP Metabolism Regulates Reproductive Aging
Lee, Y.-T.; Savini, M.; Chen, T.; Yang, J.; Zhao, Q.; Ding, L.; Gao, S. M.; Senturk, M.; Sowa, J.; Wang, J. D.; Wang, M. C.
10.1101/2023.04.02.535296 — cell biology — Posted on 2023-04-03
3924 An extended Tudor domain within Vreteno interconnects Gtsf1L and Ago3 for piRNA biogenesis in Bombyx mori
Bronkhorst, A. W.; Lee, C.; Moeckel, M.; Ruegenberg, S.; de Jesus Domingues, A.; Sadouki, S.; Sumiyoshi, T.; Siomi, M. C.; Stelzl, L.; Luck, K.; Ketting, R. F.
10.1101/2023.03.23.533951 — molecular biology — Posted on 2023-04-03
3926 QCT-based computational bone strength assessment updated with MRI derived 'hidden' microporosity
McPhee, S.; Kershaw, L. E.; Daniel, C. R.; Pena Fernandez, M.; Cillan-Garcia, E.; Taylor, S. E.; Wolfram, U.
10.1101/2023.03.30.534902 — bioengineering — Posted on 2023-04-02
3927 Adaptive evolution in virulence effectors of the rice blast fungus Pyricularia oryzae
Le Naour--Vernet, M.; Charriat, F.; Gracy, J.; Cros-Arteil, S.; Ravel, S.; Veillet, F.; Meusnier, I.; Padilla, A.; Kroj, T.; Cesari, S.; Gladieux, P.
10.1101/2023.03.16.532886 — evolutionary biology — Posted on 2023-04-03
3929 Periostin facilitates ovarian cancer recurrence by enhancing cancer stemness
Huang, Z.; Byrd, O.; Tan, S.; Knight, B.; Lo, G.; Taylor, L.; Berchuck, A.; Murphy, S. K.
10.1101/2023.03.30.534465 — cancer biology — Posted on 2023-04-02
3931 A Database of Restriction Maps to Expand the Utility of Bacterial Artificial Chromosomes
Winden, E.; Alejandro Vasquez-Echeverri, A.; Calle-Casteneda, S.; Lian, Y.; Hernandez-Ortiz, J. P.; Schwartz, D. C.
10.1101/2023.03.31.535162 — genomics — Posted on 2023-04-02
3938 Modeling Braf-induced thyroid cancer development and drug screening using pluripotent stem cell-derived organoids
Lassole, H.; Schiavo, A. A.; Tourneur, A.; Gilotay, P.; da Fonseca, B. d. F.; Ceolin, L.; Monestier, O.; Aganahi, B.; Chomette, L.; Polisel, M. K.; Haenabalcke, L.; Pieters, T.; Goossens, S.; Haigh, J.; Detours, V.; Maia, A. L.; Costagliola, S.; Romitti, M.
10.1101/2023.03.30.534915 — cancer biology — Posted on 2023-04-02
3940 Revisiting the role of Acinetobacter sp. in EBPR systems
Yan, Y.; Han, I.; Lee, J.; Li, G.; Srinivasan, V.; McCullough, K.; Klaus, S.; Kang, D.; Wang, D.; Patel, A.; McQuarrie, J.; Stinson, B. M.; deBarbadillo, C.; Dombrowski, P.; Bott, C.; Gu, A. Z.
10.1101/2023.04.01.535225 — bioengineering — Posted on 2023-04-02
3942 SLC26A2-mediated sulfate metabolism is essential for the tooth development
Yoshida, Y.; Inubushi, T.; Yokoyama, M.; Nag, P.; Oka, A.; Murotani, T.; Kani, R.; Shiraishi, Y.; Kurosaka, H.; Takahata, Y.; Nishimura, R.; Papagerakis, P.; Yamashiro, T.
10.1101/2023.03.30.534919 — developmental biology — Posted on 2023-04-02
3943 Programmable enveloped delivery vehicles for human genome engineering in vivo
Hamilton, J. R.; Chen, E.; Perez, B. S.; Sandoval Espinoza, C. R.; Kang, M. H.; Trinidad, M.; Doudna, J. A.
10.1101/2022.08.24.505004 — genomics — Posted on 2023-04-02
3948 Uncovering the Environmental Conditions Required for Phyllachora maydis Infection and Tar Spot Development on Corn in the United States for Use as Predictive Models for Future Epidemics
Webster, R. W.; Nicolli, C.; Allen, T. W.; Bish, M. D.; Bissonette, K.; Check, J. C.; Chilvers, M. I.; Duffeck, M. R.; Kleczewski, N.; Luis, J. M.; Mueller, B. D.; Price, P. P.; Paul, P.; Robertson, A. E.; Ross, T. J.; Schmidt, C.; Schmidt, R.; Schmidt, T.; Shim, S.; Telenko, D. E. P.; Wise, K.; Smith, D. L.
10.1101/2023.03.18.533264 — plant biology — Posted on 2023-04-02
3951 gUMI-BEAR, a modular, unsupervised population barcoding method to track variants and evolution at high resolution
Rezenman, S.; Knafo, M.; Tsigalnitski, I.; Barad, S.; Jona, G.; Levi, D.; Dym, O.; Reich, Z.; kapon, r.
10.1101/2022.09.01.506035 — evolutionary biology — Posted on 2023-04-02
3954 Carbon Burial in Sediments below Seaweed Farms
Duarte, C. C.; Delgado-Huertas, A. A.; Marti, E. E.; Gasser, B. B.; San Martin, I. I.; Cousteau, A. A.; Neumeyer, F. F.; Reilly-Cayten, M. M.; Boyce, J. J.; Kuwae, T. T.; Hori, M. M.; Miyajima, T. T.; Price, N. N.; Arnold, S. S.; Martinez-Ricart, A. A.; Davis, S. S.; Surugau, N. N.; Abdul, A.-J. A.; Wu, J. J.; Xi, X. X.; Chung, I. K. I.; Choi, C. G. C.; Sondak, C. F. A. C.; Albasri, H. H.; Krause-Jensen, D. D.; Bruhn, A. A.; Boderskov, T. T.; Hancke, K. K.; Funderud, J. J.; Borrero, A. A.; Pascal, F. F.; Joanne, P. P.; Ranivoarivelo, L. L.; Collins, W. T. W.; Gutierrez, J. F. J.; Riquelme, R.
10.1101/2023.01.02.522332 — ecology — Posted on 2023-04-02
3962 α-synuclein expression in response to bacterial ligands and metabolites in gut enteroendocrine cells
Hurley, M. J.; Menozzi, E.; Koletsi, S.; Bates, R.; Gegg, M. E.; Chau, K.-Y.; Blottiere, H. M.; Macnaughtan, J.; Schapira, A. H. V.
10.1101/2023.04.02.535274 — neuroscience — Posted on 2023-04-02
3964 Development and Validation of a Novel Instrument to Capture Companion Dog Mortality Data: The Dog Aging Project End of Life Survey
McNulty, K. E.; Creevy, K. E.; Fitzpatrick, A. L.; Wilkins, V.; Barnett, B. G.; Dog Aging Project Consortium, ; Ruple, A.
10.1101/2023.04.01.535178 — animal behavior and cognition — Posted on 2023-04-02
3966 Immunoproteasome deficiency results in accelerated brain aging and epilepsy
Leister, H.; Krause, F. F.; Gil, B.; Prus, R.; Prus, I.; Hellhund-Zingel, A.; Mitra, M.; Da Rosa Gerbatin, R.; Delanty, N.; Beausang, A.; Brett, F. M.; Farrell, M. A.; Cryen, J.; O'Brien, D. F.; Henshall, D.; Helmprobst, F.; Pagenstecher, A.; Steinhoff, U.; Visekruna, A.; Engel, T.
10.1101/2023.03.30.534913 — neuroscience — Posted on 2023-04-02
3967 A single neuron in C. elegans orchestrates multiple motor outputs through parallel modes of transmission
Huang, Y.-C.; Luo, J.; Huang, W.; Baker, C. M.; Gomes, M. A.; Byrne, A. B.; Flavell, S. W.
10.1101/2023.04.02.532814 — neuroscience — Posted on 2023-04-02
3969 Induced neural phase precession through exogeneous electric fields
Wischnewski, M.; Tran, H.; Zhao, Z.; Shirinpour, S.; Haigh, Z. J.; Rotteveel, J.; Alekseichuk, I.; Zimmermann, J.; Opitz, A.
10.1101/2023.03.31.535073 — neuroscience — Posted on 2023-04-02
3971 Neuronal and Astrocyte Insulin-like Growth Factor-1 Signaling Differentially Modulates Ischemic Stroke Damage
Hayes, C.; Morgan, N. I.; Thomas, K.; Pushie, M. J.; Vijayasankar, A.; Ashmore, B.; Wontor, K.; De Leon, M.; Ashpole, N.
10.1101/2023.04.02.535245 — neuroscience — Posted on 2023-04-02
3980 Defective Schwann cell lipid metabolism alters plasma membrane dynamics in Charcot-Marie-Tooth disease 1A
Prior, R.; Silva, A.; Vangansewinkel, T.; Idkowiak, J.; Kumar Tharkeshwar, A.; Hellings, T. P.; Michailidou, I.; Vreijling, J.; Loos, M.; Koopmans, B.; Vlek, N.; Straat, N.; Agaser, C.; Kuipers, T.; Michiels, C.; Rossaert, E.; Verschoren, S.; Vermeire, W.; de Laat, V.; Dehairs, J.; Eggermont, K.; van den Biggelaar, D.; Bademosi, A. T.; Meunier, F. A.; vandeVen, M.; Van Damme, P.; Mei, H.; Swinnen, J. V.; Lambrichts, I.; Baas, F.; Fluiter, K.; Wolfs, E.; Van Den Bosch, L.
10.1101/2023.04.02.535224 — neuroscience — Posted on 2023-04-02
3983 A Suite of Mouse Reagents for Studying Amelogenesis
Wald, T.; Verma, A.; Cooley, V.; Marangoni, P.; Cazares, O.; Sharir, A.; Sandoval, E. J.; Sung, D.; Najibi, H.; Drennon, T. Y.; Bush, J. O.; Joester, D.; Klein, O. D.
10.1101/2023.03.30.534992 — cell biology — Posted on 2023-04-02
3987 The carboxyl-terminal sequence of PUMA binds to both anti-apoptotic proteins and membranes.
Pemberton, J. M.; Osterlund, E. J.; Schoormann, W.; Pogmore, J.; Nguyen, D.; Leber, B.; Andrews, D.
10.1101/2023.04.02.535249 — cell biology — Posted on 2023-04-02
3988 Frustrated Microphase Separation Produces Interfacial Environment within Biological Condensates
Latham, A. P.; Zhu, L.; Sharon, D. A.; Ye, S.; Willard, A. P.; Zhang, X.; Zhang, B.
10.1101/2023.03.30.534967 — biophysics — Posted on 2023-04-02
3991 Protein language models can capture protein quaternary state
Avraham, O.; Tsaban, T.; Ben-Aharon, Z.; Tsaban, L.; Schueler-Furman, O.
10.1101/2023.03.30.534955 — bioinformatics — Posted on 2023-04-02
3992 Selective inhibition of OSBP blocks retrograde trafficking by inducing partial Golgi degradation
He, N.; Depta, L.; Rossetti, C.; Cigler, M.; Michon, M.; Dan, O. R.; Hoock, J. G. F.; Barbier, J.; Gillet, D.; Forrester, A.; Winter, G. E.; Laraia, L.
10.1101/2023.04.01.534865 — cell biology — Posted on 2023-04-02
3993 A survey of Rare Disease awareness among healthcare professionals and researchers in India
Vashishta, L.; Bapat, P.; Battacharya, Y.; Chakarborty, M.; Chirmule, N.; D'Costa, S.; Jindani, S.; Rao, M.; Sheth, S.
10.1101/2023.03.31.534989 — scientific communication and education — Posted on 2023-04-02
3998 CilioGenics: an integrated method and database for predicting novel ciliary genes
Pir, M. S.; Yenisert, F.; Karaman, A.; Begar, E.; Tsiropoulou, S.; Firat-Karalar, E. N.; Blacque, O. E.; Oner, S. S.; Doluca, O.; Cevik, S.; Kaplan, O. I.
10.1101/2023.03.31.535034 — bioinformatics — Posted on 2023-04-02
3999 A Bayesian method to infer copy number clones from single-cell RNA and ATAC sequencing
Patruno, L.; Milite, S.; Bergamin, R.; Calonaci, N.; D'Onofrio, A.; Anselmi, F.; Antoniotti, M.; Graudenzi, A.; Caravagna, G.
10.1101/2023.04.01.535197 — bioinformatics — Posted on 2023-04-02
4003 AI-based novel-chemotype GPCRs drugs: introducing ligand type classifiers and systems biology
Gossen, J.; Ribeiro, R. P.; Bier, D.; Neumaier, B.; Carloni, P.; Giorgetti, A.; Rossetti, G.
10.1101/2023.03.31.535043 — bioinformatics — Posted on 2023-04-02
4004 Alloreactivity and autoreactivity converge to support B cell epitope targeting in transplant rejection
Killian, J. T.; King, R. G.; Kizziah, J. L.; Fucile, C. F.; Diaz-Avalos, R.; Qiu, S.; Silva-Sanchez, A.; Mousseau, B. J.; Macon, K. J.; Callahan, A. R.; Yang, G.; Hossain, M. E.; Akther, J.; Houp, J. A.; Rosenblum, F. D.; Porrett, P. M.; Ong, S. C.; Kumar, V.; Mobley, J.; Saphire, E. O.; Kearney, J. F.; Randall, T. D.; Rosenberg, A. F.; Green, T. J.; Lund, F. E.
10.1101/2023.03.31.534734 — immunology — Posted on 2023-04-02
4005 Cell polarity linked to gravity sensing is generated by protein translocation from statoliths to the plasma membrane.
Nishimura, T.; Mori, S.; Shikata, H.; Nakamura, M.; Hashiguchi, Y.; Abe, Y.; Hagihara, T.; Yoshikawa, H. Y.; Toyota, M.; Higaki, T.; Morita, M. T.
10.1101/2023.03.31.534658 — plant biology — Posted on 2023-04-02
4007 Spatially Resolved Transcriptomics Mining in 3D and Virtual Reality Environments with VR-Omics
Bienroth, D.; Charitakis, N.; Jaeger-Honz, S.; Garkov, D.; Elliot, D.; Porrello, E. R.; Klein, K.; Nim, H. T.; Schreiber, F.; Ramialison, M.
10.1101/2023.03.31.535025 — bioinformatics — Posted on 2023-04-02
4008 PanKmer: k-mer based and reference-free pangenome analysis
Aylward, A. J.; Petrus, S.; Mamerto, A.; Hartwick, N. T.; Michael, T. P.
10.1101/2023.03.31.535143 — bioinformatics — Posted on 2023-04-02
4011 Connectivity-based Meta-Bands: A new approach for automatic frequency band identification in connectivity analyses
Rodriguez-Gonzalez, V.; Nunez, P.; Gomez, C.; Shigihara, Y.; Hoshi, H.; Tola-Arribas, M. A.; Cano, M.; Guerrero, A.; Garcia-Azorin, D.; Hornero, R.; Poza, J.
10.1101/2023.03.30.534879 — bioinformatics — Posted on 2023-04-02
4015 Integrated Phenomics and Genomics reveals genetic loci associated with inflorescence growth in Brassica napus
Williams, K.; Hepworth, J.; Nichols, B. S.; Corke, F. M. K.; Woolfenden, H. C.; Paajanen, P.; Steuernagel, B.; Ostergaard, L.; Morris, R. J.; Doonan, J. H.; Wells, R.
10.1101/2023.03.31.535149 — plant biology — Posted on 2023-04-02
4017 Rescue of blood coagulation Factor VIII exon-16 mis-splicing by antisense oligonucleotides
Tse, V.; Chacaltana, G.; Gutierrez, M.; Nicholas, F. M.; Jimenez, A. G.; Tao, H.; Do, P. H.; Oh, C.; Chary, P.; Quesada, I.; Hamrick, A.; Lee, S.; Stone, M. D.; Sanford, J. R.
10.1101/2023.03.31.535160 — molecular biology — Posted on 2023-04-01
4018 Bradykinin receptor expression and bradykinin-mediated sensitization of human sensory neurons
Yi, J.; Bertels, Z.; Del Rosario, J. S.; Widman, A. J.; Slivicki, R. A.; Payne, M.; Susser, H. M.; Copits, B. A.; Gereau, R. W.
10.1101/2023.03.31.534820 — neuroscience — Posted on 2023-04-01
4019 Phencyclidine disrupts neural coordination and cognitive control by dysregulating translation
Park, E.; Kao, H.-Y.; Jourdi, H.; van Dijk, M.; Carrillo-Segura, S.; Tunnell, K. W.; Gutierrez, J.; Wallace, E. J.; Troy-Regier, M.; Radwan, B.; Lesburgueres, E.; Alarcon, J. M.; Fenton, A. A.
10.1101/2022.11.18.517075 — neuroscience — Posted on 2023-04-01
4020 Autophagy in maternal tissues contributes to Arabidopsis thaliana seed development.
Erlichman, O.; Weiss, S.; Abu-Arkia, M.; Khaner, M. A.; Soroka, Y.; Jasinska, W.; Rosental, L.; Brotman, Y.; Avin-Wittenberg, T.
10.1101/2023.02.27.530228 — plant biology — Posted on 2023-04-01
4021 A rapid alkalinization factor-like peptide EaF82 impairs tapetum degeneration during pollen development through induced ATP deficiency
Hung, C.-Y.; Kittur, F.; Wharton, K.; Umstead, M.; Burwell, D.; Thomas, M.; Qi, Q.; Zhang, J.; Oldham, C. E.; Burkey, K. O.; Chen, J.; Xie, J. J.
10.1101/2022.08.11.503650 — plant biology — Posted on 2023-04-01
4023 Structural insights into the complex of oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator
Tariq, M.; Ikeya, T.; Togashi, N.; Fairall, L.; Bueno-Alejo, C.; Kamei, S.; Romartinez-Alonso, B.; Muro Campillo, M. A.; Hudson, A. J.; Ito, Y.; Schwabe, J. W.; Dominguez, C.; Tanaka, K.
10.1101/2022.10.10.511529 — biochemistry — Posted on 2023-04-01
4028 Single-cell multi-omic analysis of thymocyte development reveals drivers of CD4/CD8 lineage commitment
Steier, Z.; Aylard, D. A.; McIntyre, L. L.; Baldwin, I.; Kim, E. J. Y.; Lutes, L. K.; Ergen, C.; Huang, T.-S.; Robey, E. A.; Yosef, N.; Streets, A.
10.1101/2021.07.12.452119 — immunology — Posted on 2023-04-01
4031 Dysregulated Wnt and NFAT signaling in a Parkinson's disease LRRK2 G2019S knock-in model
Wetzel, A.; Lei, S. H.; Liu, T.; Hughes, M. P.; Peng, Y.; McKay, T.; Waddington, S. N.; Granno, S.; Rahim, A. A.; Harvey, K.
10.1101/2023.03.31.535090 — neuroscience — Posted on 2023-04-01
4035 Expanding the coverage of regulons from high-confidence prior knowledge for accurate estimation of transcription factor activities
Mueller-Dott, S.; Tsirvouli, E.; Vazquez, M.; Ramirez Flores, R. O.; Badia-i-Mompel, P.; Fallegger, R.; Lagreid, A.; Saez-Rodriguez, J.
10.1101/2023.03.30.534849 — bioinformatics — Posted on 2023-04-01
4036 A broad-spectrum family GH13 α-glucosidase from Marinovum sp., a member of the Roseobacter clade
Li, J.; Mui, J. W.- Y.; da Silva, B. M.; Pires, D. E. V.; Ascher, D. B.; Madiedo Soler, N.; Goddard-Borger, E. D.; Williams, S. J.
10.1101/2023.03.31.535182 — biochemistry — Posted on 2023-04-01
4037 A role for cytoglobin in regulating intracellular hydrogen peroxide and redox signals in the vasculature
Mathai, C.; Jourd'heuil, F. L.; Pham, L. G. C.; Gilliard, K.; Balnis, J.; Jen, A.; Overmyer, K. A.; Coon, J. J.; Jaitovich, A.; Boivin, B.; Jourd'heuil, D.
10.1101/2023.03.31.535146 — biochemistry — Posted on 2023-04-01
4040 Impact of pathogen genetics on clinical phenotypes in a population of Talaromyces marneffei from Vietnam
Sephton-Clark, P.; Nguyen, T.; Hoa, N. T.; Ashton, P.; van Doorn, R.; Ly, V. T.; Le, T.; Cuomo, C. A.
10.1101/2023.03.30.534926 — genomics — Posted on 2023-04-01
4041 An integrated map of genetic variation from 1,062 wheat genomes
Bi, A.; Xu, D.; Kang, L.; Guo, Y.; Song, X.; Zhao, X.; Zhang, J.; Zhang, Z.; Li, Y.; Yin, C.; Wang, J.; Lu, F.
10.1101/2023.03.31.535022 — genomics — Posted on 2023-04-01
4042 Microtomographic investigation of a large corpus of cichlids
Haberthür, D.; Law, M.; Ford, K.; Häsler, M.; Seehausen, O.; Hlushchuk, R.
10.1101/2023.03.30.534917 — ecology — Posted on 2023-04-01
4043 Spatial consistency of cell growth direction during organ morphogenesis requires CELLULOSE-SYNTHASE INTERACTIVE1
Mollier, C.; Skrzydeł, J.; Borowska-Wykret, D.; Majda, M.; Bayle, V.; Battu, V.; Totozafy, J.-C.; Dulski, M.; Fruleux, A.; Wrzalik, R.; Mouille, G.; Smith, R.; Moneger, F.; Kwiatkowska, D.; Boudaoud, A.
10.1101/2022.07.27.501687 — developmental biology — Posted on 2023-04-01
4048 Vangl2 suppresses NF-κB signaling and ameliorates sepsis by targeting p65 for NDP52-mediated autophagic degradation
Lu, J.; Zhang, J.; Jiang, H.; Hu, Z.; He, L.; Yang, J.; Xie, Y.; Wu, D.; Li, H.; Zeng, K.; Tan, P.; Xiao, Q.; Song, Z.; Bai, X.; Yu, X.
10.1101/2023.03.30.534894 — immunology — Posted on 2023-04-01
4051 Analysis of Arabidopsis venosa4-0 supports the role of VENOSA4 in dNTP homeostasis
Sarmiento-Manus, R.; Gonzalez-Bayon, R.; Fontcuberta-Cervera, S.; Hannah, M. A.; Alvarez-Martinez, F. J.; Barrajon-Catalan, E.; Micol, V.; Quesada, V.; Ponce, M. R.; Micol, J. L.
10.1101/2023.03.30.534755 — plant biology — Posted on 2023-04-01
4053 Advancing Understanding of DNA-BfiI Restriction Endonuclease Cis and Trans Interactions through smFRET Technology
Tutkus, M.; Ivanovaite, S.; Paksaite, J.; Kopustas, A.; Karzaite, G.; Rutkauskas, D.; Silanskas, A.; Sasnauskas, G.; Zaremba, M.; Jones, S. K.
10.1101/2023.03.31.535070 — biophysics — Posted on 2023-04-01
4055 Regulation of Human PINK1 ubiquitin kinase by Serine167, Serine228 and Cysteine412 phosphorylation
Waddell, A.; Ojha, H.; Agarwal, S.; Clarke, C.; Terriente-Felix, A.; Zhou, H.; Kakade, P.; Knebel, A.; Shaw, A.; Gourlay, R.; Varghese, J.; Soares, R.; Toth, R.; Macartney, T.; Eyers, P.; Morrice, N.; Bayliss, R.; Whitworth, A. J.; Eyers, C.; Muqit, M.
10.1101/2023.03.31.534916 — biochemistry — Posted on 2023-04-01
4056 Structure of the human Bre1 complex bound to the nucleosome
Onishi, S.; Uchiyama, K.; Sato, K.; Okada, C.; Kobayashi, S.; Nishizawa, T.; Nureki, O.; Ogata, K.; Sengoku, T.
10.1101/2023.03.31.535082 — biochemistry — Posted on 2023-04-01
4057 The small mycobacterial ribosomal protein, bS22, modulates aminoglycoside accessibility to its 16S rRNA helix-44 binding site
Majumdar, S.; Deep, A.; Sharma, M. R.; Canestrari, J.; Stone, M.; Smith, C.; Koripella, R. K.; Keshavan, P.; Banavali, N. K.; Wade, J.; Gray, T. A.; Derbyshire, K. M.; Agrawal, R. K.
10.1101/2023.03.31.535098 — biochemistry — Posted on 2023-04-01
4058 DNA sequence context and the chromatin landscape differentiate sequence-specific transcription factor binding in the human malaria parasite, Plasmodium falciparum
Bonnell, V. A.; Zhang, Y.; Brown, A. S.; Horton, J.; Josling, G. A.; Chiu, T.-P.; Rohs, R.; Mahony, S.; Gordan, R.; Llinas, M.
10.1101/2023.03.31.535174 — genomics — Posted on 2023-04-01
4062 Characterization of regeneration initiating cells during Xenopus laevis tail regeneration
Sindelka, R.; Abaffy, P.; Zucha, D.; Naraine, R.; Kraus, D.; Netusil, J.; Smetana, K.; Lukas, L.; Endaya, B. B.; Neuzil, J.; Psenicka, M.; Kubista, M.
10.1101/2023.03.30.534908 — developmental biology — Posted on 2023-04-01
4065 Dissecting the Ca2+ dependence of Mycobacterium tuberculosis DesA1 function
Savanagouder, M.; Mukku, R. P.; Kiran, U.; Yeruva, C. V.; Nagarajan, N.; Sharma, Y.; Raghunand, T. R.
10.1101/2023.03.31.535087 — microbiology — Posted on 2023-04-01
4066 Inflammation and bacteriophages affect DNA inversion states and functionality of the gut microbiota
Carasso, S.; Zaatry, R.; Hajjo, H.; Kadosh-Kariti, D.; Ben-Assa, N.; Naddaf, R.; Mandelbaum, N.; Pressman, S.; Chowers, Y.; Gefen, T.; Jeffrey, K. L.; Jofre, J.; Coyne, M. J.; Comstock, L. E.; Sharon, I.; Geva-Zatorsky, N.
10.1101/2023.03.31.535104 — microbiology — Posted on 2023-04-01
4067 Dynamic microfluidic single-cell screening identifies pheno-tuning compounds to potentiate tuberculosis therapy
Mistretta, M.; Cimino, M.; Campagne, P.; Volant, S.; Kornobis, E.; Hebert, O.; Rochais, C.; Dallemagne, P.; Lecoutey, C.; Tisnerat, C.; Lepailleur, A.; Ayotte, Y.; LaPlante, S. R.; Gangneux, N.; Zahorszka, M.; Kordulakova, J.; Vichier-Guerre, S.; Bonhomme, F.; Pokorny, L.; Albert, M.; Tinevez, J.-Y.; Manina, G.
10.1101/2023.03.31.535085 — microbiology — Posted on 2023-04-01
4068 Assessing Microbial Diversity in Soil Samples Along the Potomac River: Implications for Environmental Health
Taraboletti, A. A.; King, A.; Dixon, Y.; Orr, O.; Parnell, C.; Watson, Y.; Nash, B.; Esimai, C.; Ude, G.
10.1101/2023.03.31.535185 — microbiology — Posted on 2023-04-01
4069 Staphylococcus aureus biofilm secreted factors cause mucosal damage, mast cell infiltration and goblet cell hyperplasia in a rat rhinosinusitis model
Houtak, G.; Nepal, R.; Bouras, G.; Shaghayegh, G.; Bennett, C.; Finnie, J.; Fenix, K.; Psaltis, A. J.; Wormald, P.-J.; Vreugde, S.
10.1101/2023.03.29.534842 — immunology — Posted on 2023-04-01
4070 Dietary environmental factors shape the defence against infection with Cryptosporidium
Sateriale, A.; Maradana, M. R.; Marzook, N. B.; Diaz Perez, O.; Mkandawire, T.; Diny, N. L.; Li, Y.; Liebert, A.; Shah, K.; Tolaini, M.; Kvac, M.; Stockinger, B.
10.1101/2023.03.30.534739 — immunology — Posted on 2023-04-01
4071 Genetic impacts on DNA methylation help elucidate regulatory genomic processes
Villicana, S.; Castillo-Fernandez, J.; Hannon, E.; Christiansen, C.; Tsai, P.-C.; Maddock, J.; Kuh, D.; Suderman, M.; Power, C.; Relton, C.; Ploubidis, G.; Wong, A.; Hardy, R.; Goodman, A.; Ong, K. K.; Bell, J. T.
10.1101/2023.03.31.535045 — genomics — Posted on 2023-04-01
4078 SERPINB3 induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer
Ohara, Y.; Tang, W.; Liu, H.; Yang, S.; Dorsey, T. H.; Cawley, H.; Moreno, P.; Azizian, A.; Gaedcke, J.; Ghadimi, B. M.; Hanna, N.; Ambs, S.; Hussain, S. P.
10.1101/2023.03.29.534766 — cancer biology — Posted on 2023-04-01
4079 Characterization of uranyl ion binding to amyloid beta (Aβ) peptides: effects on Aβ structure and aggregation
Berntsson, E.; Vosough, F.; Noormagi, A.; Padari, K.; Asplund, F.; Gielnik, M.; Paul, S.; Jarvet, J.; Tougu, V.; Roos, P. M.; Kozak, M.; Graslund, A.; Barth, A.; Pooga, M.; Palumaa, P.; Warmlander, S. K. T. S.
10.1101/2023.03.29.534802 — biophysics — Posted on 2023-04-01
4086 A high-throughput multiplex array for antigen-specific serology with automated analysis.
Rosenberg, A. F.; Killian, J. T.; Green, T. J.; Akther, J.; Hossain, E.; Qiu, S.; Randall, T. D.; Lund, F. E.; King, R. G.
10.1101/2023.03.29.534777 — immunology — Posted on 2023-04-01
4090 Distinct mesenchymal cell states mediate prostate cancer progression
Pakula, H.; Omar, M.; Carelli, R.; Pederzoli, F.; Fanelli, G. N.; Pannellini, T.; Van Emmenis, L.; Rodrigues, S.; Fidalgo-Ribeiro, C.; Nuzzo, P. V.; Brady, N. J.; Jere, M.; Unkenholz, C.; Alexanderani, M. K.; Khani, F.; de Almeida, F. N.; Abate-Shen, C.; Greenblatt, M. B.; Rickman, D. S.; Barbieri, C. E.; Robinson, B. D.; Marchionni, L.; Loda, M.
10.1101/2023.03.29.534769 — cancer biology — Posted on 2023-04-01
4091 Assessing Random Forest self-reproducibility for optimal short biomarker signature discovery
Poulet, C.; Debit, A.; Josse, C.; Jerusalem, G.; Azencott, C.-A.; Bours, V.; Van Steen, K.
10.1101/2023.03.29.534695 — bioinformatics — Posted on 2023-04-01
4092 Split-Transformer Impute (STI): Genotype Imputation Using a Transformer-Based Model
Mowlaei, M. E.; Li, C.; Chen, J.; Jamialahmadi, B.; Kumar, S.; Rebbeck, T. R.; Shi, X.
10.1101/2023.03.05.531190 — genomics — Posted on 2023-04-01
4093 Molecular basis of sulfolactate synthesis by sulfolactaldehyde dehydrogenase from Rhizobium leguminosarum
Li, J.; Sharma, M.; Meek, R. W.; Alhifthi, A.; Armstrong, Z.; Madiedo Soler, N.; Goddard-Borger, E. D.; Blaza, J. N.; Davies, G. J.; Williams, S. J.
10.1101/2023.03.13.532361 — biochemistry — Posted on 2023-04-01
4094 Membrane-induced 2D phase separation of focal adhesion proteins
Litschel, T.; Kelley, C. F.; Cheng, X.; Babl, L.; Mizuno, N.; Case, L. B.; Schwille, P.
10.1101/2023.03.31.535113 — cell biology — Posted on 2023-04-01
4095 Metastatic breast cancer cells have reduced calcium and actin response after ATP-P2Y2 signaling
Mull, M. L.; Pratt, S. J. P.; Thompson, K. N.; Annis, D. A.; Gad, A. A.; Lee, R. M.; Chang, K. T.; Stemberger, M. B.; Ju, J. A.; Gilchrist, D. E.; Boyman, L.; Vitolo, M. I.; Lederer, W. J.; Martin, S. S.
10.1101/2023.03.31.533191 — cancer biology — Posted on 2023-04-01
4097 An Image-Guided Microfluidic System for Single-Cell Lineage Tracking
Aslan, M. K.; Fourneaux, C.; Yilmaz, A.; Stavros, S.; Parmentier, R.; Paldi, A.; Gonin-Giraud, S.; deMello, A. J.; Gandrillon, O.
10.1101/2023.03.31.535033 — cell biology — Posted on 2023-04-01
4098 Vimentin cysteine 328 modifications finely tune network organization and influence actin remodeling under oxidative and electrophilic stress
Gonzalez-Jimenez, P.; Duarte, S.; Martinez, A. E.; Navarro-Carrasco, E.; Lalioti, V.; Pajares, M. A.; Perez-Sala, D.
10.1101/2023.03.30.534617 — cell biology — Posted on 2023-04-01
4101 Stress-induced clustering of the UPR sensor IRE1 is driven by disordered regions within its ER lumenal domain
Kettel, P.; Marosits, L.; Spinetti, E.; Rechberger, M.; Radler, P.; Niedermoser, I.; Fischer, I.; Versteeg, G. A.; Loose, M.; Covino, R.; Karagoz, G. E.
10.1101/2023.03.30.534746 — cell biology — Posted on 2023-04-01