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Archive, 2020-03

3 Specialisation and plasticity in a primitively social insect
Patalano, S.; Alsina, A.; Gregorio-Rodriguez, C.; Bachman, M.; Dreier, S.; Hernando-Herraez, I.; Nana, P.; Balasubramanian, S.; Sumner, S.; Reik, W.; Rulands, S.
10.1101/2020.03.31.007492 — biophysics — Posted on 2020-03-31
4 Intra-articular AAV-PHP.S mediated chemogenetic targeting of knee-innervating dorsal root ganglion neurons alleviates inflammatory pain in mice.
Chakrabarti, S.; Pattison, L. A.; Doleschall, B.; Rickman, R.; Blake, H.; Callejo, G.; Heppenstall, P. A.; Smith, E. S. J.
10.1101/2020.02.08.939066 — neuroscience — Posted on 2020-03-31
7 Genome architecture and transcription data reveal allelic bias during the cell cycle
Lindsly, S. M.; Jia, W.; Chen, H.; Ronquist, S.; Chen, C.; Wen, X.; Li, S. C.; Wicha, M.; Rehemtulla, A.; Muir, L.; Rajapakse, I.
10.1101/2020.03.15.992164 — bioinformatics — Posted on 2020-03-31
10 A way to break bones? The weight of intuitiveness
Vettese, D.; Stavrova, T.; Borel, A.; Marin, J.; Moncel, M.-H.; Arzarello, M.; Daujeard, C.
10.1101/2020.03.31.011320 — paleontology — Posted on 2020-03-31
13 Centrality of the XBP1-ERN1 axis in transplacental innate immune training via a microbial-derived immunomodulator
Mincham, K. T.; Jones, A. C.; Bodinier, M.; Scott, N. M.; Lauzon-Joset, J.-F.; Stumbles, P. A.; Bosco, A.; Holt, P. G.; Strickland, D. H.
10.1101/848242 — immunology — Posted on 2020-03-31
22 Emotional responsiveness task in emotional distress: correlated of functional neuroimaging in anorexia and bulimia
D'Agata, F.; Caroppo, P.; Spalatro, A.; Lavagnino, L.; Abbate Daga, G.; Boghi, A.; Bergui, M.; Cicerale, A.; Vitiello, B.; Fassino, S.; Derntl, B.; Amianto, F.
10.1101/2020.03.31.018424 — neuroscience — Posted on 2020-03-31
24 Gut microbial genes are associated with neurocognition and brain development in healthy children
Bonham, K. S.; Bruchhage, M. M. K.; Rowland, S.; Volpe, L.; Dyer, K.; RESONANCE Consortium, ; D'Sa, V.; Huttenhower, C.; Deoni, S.; Klepac-Ceraj, V.
10.1101/2020.02.13.944181 — microbiology — Posted on 2020-03-31
28 A recombinant gp145 Env glycoprotein from HIV-1 expressed in two different cell lines: effects on glycosylation and antigenicity
Gonzalez-Feliciano, J. A.; Akamine, P. Y.; Capo-Velez, C. M.; Delgado-Velez, M.; Dussupt, V.; Krebs, S. J.; Wojna, V.; Polonis, V. R.; Baerga-Ortiz, A.; Lasalde-Dominicci, J. A.
10.1101/2020.03.31.018408 — biochemistry — Posted on 2020-03-31
30 A neural code for egocentric spatial maps in the human medial temporal lobe
Kunz, L.; Brandt, A.; Reinacher, P. C.; Staresina, B. P.; Reifenstein, E. T.; Weidemann, C. T.; Herweg, N. A.; Tsitsiklis, M.; Kempter, R.; Kahana, M. J.; Schulze-Bonhage, A.; Jacobs, J.
10.1101/2020.03.03.973131 — neuroscience — Posted on 2020-03-31
34 Polygenic adaptation of rosette growth variation in Arabidopsis thaliana populations
de Meaux, J.; Wieters, B.; Steige, K.; He, F.; Koch, E.; Ramos-Onsins, S.; Gu, H. Y.; Guo, Y.; Sunyaev, S.
10.1101/2020.03.31.018341 — evolutionary biology — Posted on 2020-03-31
35 Live imaging defines the dynamics and molecular basis of in vivo mitophagy
Wrighton, P. J.; Shwartz, A.; Heo, J.-M.; Quenzer, E. D.; LaBella, K. A.; Harper, J. W.; Goessling, W.
10.1101/2020.03.26.010405 — cell biology — Posted on 2020-03-31
37 Cortical stiffness of keratinocytes measured by lateral indentation with optical tweezers
Zemljic Jokhadar, S.; Stojkovic, B.; Vidak, M.; Liovic, M.; Gouveia, M.; Travasso, R. D. M.; Derganc, J.
10.1101/2020.03.31.018473 — biophysics — Posted on 2020-03-31
39 Chemical composition and larvicidal activity against Aedes mosquitoes of flower extracts from Clitoria Ternatea
Ravi, R.; Mohd Amin, M. F.; Said, A. R.; Ishak, I. H.; Srikumar, S.; Rajendran, D.; Mat Rasat, M. S.; Ramaiah, P.; Bharathithasan, M.; Ravindran, D. R.; As stated in manuscript,
10.1101/2020.03.31.018465 — biochemistry — Posted on 2020-03-31
40 RNA editing enzyme APOBEC3A promotes pro-inflammatory (M1) macrophage polarization
Alqassim, E. Y.; Sharma, S.; Khan, A. N. H.; Emmons, T.; Cortes-Gomez, E.; Singel, K.; Mark, J.; Davidson, B. A.; McGray, A. R.; Litchy, B. D.; Moysich, K.; Wang, J.; Odunsi, K.; Segal, B. H.; Baysal, B. E.
10.1101/2020.03.20.988980 — immunology — Posted on 2020-03-31
43 ULTRASOUND-ASSISTED MAGNETIC NANOPARTICLE-BASED GENE DELIVERY
Chen, J.; Zhang, W.; Abdelrasoul, G.; Savchenko, O.; Abdrabou, A.; Wang, Z.
10.1101/2020.03.31.018440 — bioengineering — Posted on 2020-03-31
46 Uptake of exogenous serine is important to maintain sphingolipid homeostasis in Saccharomyces cerevisiae
Esch, B. M.; Limar, S.; Bogdanowski, A.; Gournas, C.; More, T.; Sundag, C.; Walter, S.; Heinisch, J. J.; Ejsing, C. S.; Andre, B.; Fröhlich, F.
10.1101/2020.03.30.016220 — genetics — Posted on 2020-03-31
47 Unlocking the potential of historical abundance datasets to study biomass change in flying insects
Kinsella, R. S.; Thomas, C. D.; Crawford, T. J.; Hill, J. K.; Mayhew, P. J.; Macgregor, C. J.
10.1101/695635 — ecology — Posted on 2020-03-31
48 S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling
Geng, X.; Yanagida, K.; Akwii, R.; Choi, D.; Chen, L.; Ho, Y.; Cha, B.; Mahamud, M. R.; de Ruiz, K. B.; Ichise, H.; Chen, H.; Wythe, J.; Mikelis, C.; Hla, T.; Srinivasan, R. S.
10.1101/2020.02.27.968594 — developmental biology — Posted on 2020-03-31
49 Deep analysis of the USP18-dependent ISGylome and proteome unveils important roles for USP18 in tumour cell antigenicity and radiosensitivity
Pinto-Fernandez, A.; Salio, M.; Partridge, T.; Chen, J.; Vere, G.; Greenwood, H.; Olie, C. S.; Damianou, A.; Scott, H. C.; Diaz-Saez, L.; Smith, P.; Gonzalez-Lopez, C.; Huber, K.; Muschel, R.; Borrow, P.; Cerundolo, V.; Kessler, B. M.
10.1101/2020.03.31.005629 — cancer biology — Posted on 2020-03-31
50 Longitudinal cancer evolution from single cells
Ramazzotti, D.; Angaroni, F.; Maspero, D.; Ascolani, G.; Castiglioni, I.; Piazza, R.; Antoniotti, M.; Graudenzi, A.
10.1101/2020.01.14.906453 — bioinformatics — Posted on 2020-03-31
52 Functional ultrasound speckle decorrelation-based velocimetry of the brain
Tang, J.; Postnov, D. D.; Kilic, K.; Erdener, S. E.; Lee, B.; Szabo, T. L.; Boas, D. A.
10.1101/686774 — bioengineering — Posted on 2020-03-31
55 RNF213 variation, a broader role in neurovascular disease in Caucasian and Japanese populations
Lorenzo Betancor, O.; Blackburn, P. R.; Farrugia, L.; Soto-Beasley, A. I.; Walton, R. L.; Edwards, E.; Tawk, R. G.; Klee, E. W.; Freeman, W. D.; Miller, D.; Meschia, J.; Ross, O. A.
10.1101/2020.03.31.013078 — neuroscience — Posted on 2020-03-31
57 Whole-chromosome fusions in the karyotype evolution of Sceloporus (Iguania, Reptilia) are more intense in sex chromosomes than autosomes
Lisachov, A.; Tishakova, K.; Romanenko, S.; Molodtseva, A.; Prokopov, D.; Pereira, J.; Ferguson-Smith, M.; Borodin, P.; Trifonov, V.
10.1101/2020.03.31.011619 — genomics — Posted on 2020-03-31
61 New and improved GRAB fluorescent sensors for monitoring dopaminergic activity in vivo
Sun, F.; Zhou, J.; Dai, B.; Qian, T.; Zeng, J.; Li, X.; Zhuo, Y.; Zhang, Y.; Tan, K.; Feng, J.; Dong, H.; Qian, C.; Lin, D.; Cui, G.; Li, Y.
10.1101/2020.03.28.013722 — neuroscience — Posted on 2020-03-31
62 The Crohn's disease-related AIEC strain LF82 assembles a biofilm-like matrix to protect intracellular microcolonies from phagolysosomal attack
Prudent, V.; Demarre, G.; Vazeille, E.; Wery, M.; Ravet, A.; Quenech Du, N.; Dauverd Girault, J.; Bringer, M.-A.; Descrimes, M.; Barnich, N.; Rimsky, S.; Morillon, A.; Espeli, O.
10.1101/2020.03.31.014175 — microbiology — Posted on 2020-03-31
63 Deep learning at base-resolution reveals cis-regulatory motif syntax
Avsec, Z.; Weilert, M.; Shrikumar, A.; Krueger, S.; Alexandari, A.; Dalal, K.; Fropf, R.; McAnany, C.; Gagneur, J.; Kundaje, A.; Zeitlinger, J.
10.1101/737981 — genomics — Posted on 2020-03-31
67 Evaluation the accuracy of a smartphone-based artificial intelligence system, PlantVillage Nuru, in identifying the viral diseases of cassava
Mrisho, L. M.; Mbilinyi, N.; Ndalahwa, M.; Ramcharan, A. M.; Kehs, A.; McCloskey, P.; Murithi, H.; Hughes, D. P.; Legg, J. P.
10.1101/2020.01.26.919449 — plant biology — Posted on 2020-03-31
68 Spatial accumulation of salicylic acid is regulated by RBOHD in potato immunity against viruses
Lukan, T.; Pompe-Novak, M.; Baebler, S.; Tusek-Znidaric, M.; Kladnik, A.; Kriznik, M.; Blejec, A.; Zagorscak, M.; Stare, K.; Dusak, B.; Coll, A.; Pollmann, S.; Morgiewicz, K.; Hennig, J.; Gruden, K.
10.1101/2020.01.06.889998 — plant biology — Posted on 2020-03-31
74 Conservation Genomic Analyses of African and Asiatic Cheetahs (Acinonyx jubatus) Across Their Current and Historic Species Range.
Prost, S.; Machado, A. P.; Zumbroich, J.; Preier, L.; Mahtani-Williams, S.; Guschanski, K.; Brealey, J. C.; Fernandes, C.; Vercammen, P.; Godsall-Bottriell, L.; Bottriell, P.; Dalton, D. L.; Kotze, A.; Burger, P. A.
10.1101/2020.02.14.949081 — evolutionary biology — Posted on 2020-03-31
75 FLASH irradiation enhances the therapeutic index of abdominal radiotherapy for the treatment of ovarian cancer
Levy, K.; Natarajan, S.; Wang, J.; Chow, S.; Eggold, J. T.; Loo, P.; Manjappa, R.; Lartey, F. M.; Schüler, E.; Skinner, L.; Rafat, M.; Ko, R.; Kim, A.; Al Rawi, D.; von Eyben, R.; Dorigo, O.; Casey, K. M.; Graves, E. E.; Bush, K.; Yu, A. S.; Koong, A. C.; Maxim, P. G.; Loo, B. W.; Rankin, E. B.
10.1101/2019.12.12.873414 — cancer biology — Posted on 2020-03-31
76 De novo reconstruction of microbial haplotypes by integrating statistical and physical linkage
Cao, C.; He, J.; Mak, L.; Perera, D.; Kwok, D.; Wang, J.; Li, M.; Mourier, T.; Gavriliuc, S.; Greenberg, M.; Morrissy, S.; Sycuro, L.; Yang, G.; Jeffares, D. C.; Long, Q.
10.1101/2020.03.29.014704 — bioinformatics — Posted on 2020-03-31
77 De novo reconstruction of microbial haplotypes by integrating statistical and physical linkage
Cao, C.; He, J.; Mak, L.; Perera, D.; Kwok, D.; Wang, J.; Li, M.; Mourier, T.; Gavriliuc, S.; Greenberg, M.; Morrissy, S.; Sycuro, L.; Yang, G.; Jeffares, D. C.; Long, Q.
10.1101/2020.03.29.014704 — bioinformatics — Posted on 2020-03-31
78 Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner
Pal, A.; Al-Shaer, A. E.; Guesdon, W.; Torres, M. J.; Armstrong, M.; Quinn, K.; Davis, T.; Reisdorph, N.; Neufer, P. D.; Spangenburg, E. E.; Carroll, I.; Bazinet, R. P.; Halade, G. V.; Claria, J.; Shaikh, S. R.
10.1101/848093 — biochemistry — Posted on 2020-03-31
79 Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner
Pal, A.; Al-Shaer, A. E.; Guesdon, W.; Torres, M. J.; Armstrong, M.; Quinn, K.; Davis, T.; Reisdorph, N.; Neufer, P. D.; Spangenburg, E. E.; Carroll, I.; Bazinet, R. P.; Halade, G. V.; Claria, J.; Shaikh, S. R.
10.1101/848093 — biochemistry — Posted on 2020-03-31
80 DNA Encoded Glycan Libraries as a next-generation tool for the study of glycan-protein interactions
Kondengaden, S. M.; Zhang, J.; Zhang, H.; Parameswaran, A.; Kondengadan, S. M.; Pawar, S.; Puthengot, A.; Sunderraman, R.; Song, J.; Polizzi, S. J.; Wen, L.; Wang, P. G.
10.1101/2020.03.30.017012 — synthetic biology — Posted on 2020-03-31
82 Decoding Odor Mixtures in the Dog Brain: An Awake fMRI Study
Prichard, A.; Chhibber, R.; King, J.; Athanassiades, K.; Spivak, M.; Berns, G. S.
10.1101/754374 — neuroscience — Posted on 2020-03-31
85 Prion protein lowering is a disease-modifying therapy across prion strains, disease stages, and endpoints
Minikel, E. V.; Zhao, H. T.; Le, J.; O'Moore, J.; Pitstick, R.; Graffam, S.; Carlson, G. A.; Kriz, J.; Kim, J. B.; Ma, J.; Wille, H.; Aiken, J.; McKenzie, D.; Doh-ura, K.; Beck, M.; O'Keefe, R.; Stathopoulos, J.; Caron, T.; Schreiber, S. L.; Carroll, J. B.; Kordasiewicz, H. B.; Cabin, D. E.; Vallabh, S. M.
10.1101/2020.03.27.011940 — neuroscience — Posted on 2020-03-31
87 A memory of RPS25 loss drives resistance phenotypes
Johnson, A. G.; Flynn, R. A.; Lapointe, C. P.; Ooi, Y. S.; Zhao, M. L.; Richards, C. M.; Qiao, W.; Yamada, S. B.; Couthouis, J.; Gitler, A. D.; Carette, J. E.; Puglisi, J. D.
10.1101/805663 — molecular biology — Posted on 2020-03-31
88 COVID-19 Vaccine Candidates: Prediction and Validation of 174 SARS-CoV-2 Epitopes
Prachar, M.; Justesen, S.; Steen-Jensen, D. B.; Thorgrimsen, S. P.; Jurgons, E.; Winther, O.; Bagger, F. O.
10.1101/2020.03.20.000794 — immunology — Posted on 2020-03-31
89 Brain microRNAs among social and solitary bees
Kapheim, K. M.; Jones, B. M.; Sovik, E.; Stolle, E.; Waterhouse, R. M.; Bloch, G.; Ben-Shahar, Y.
10.1101/730317 — genomics — Posted on 2020-03-31
90 Predicting cell-type-specific non-coding RNA transcription from genome sequence
Koido, M.; Hon, C.-C.; Koyama, S.; Kawaji, H.; Murakawa, Y.; Ishigaki, K.; Ito, K.; Sese, J.; Kamatani, Y.; Carninci, P.; Terao, C.
10.1101/2020.03.29.011205 — genomics — Posted on 2020-03-31
92 Phenotypic variation in mitochondrial function across New Zealand snail populations
Greimann, E. S.; Fahrner, S.; Woodell, J. D.; Hennessey, S. K.; Kline, M. R.; Moreno, J. A.; Peters, M. R.; Cruise, J. L.; Montooth, K. L.; Neiman, M.; Sharbrough, J.
10.1101/230979 — evolutionary biology — Posted on 2020-03-31
97 Sierra: Discovery of differential transcript usage from polyA-captured single-cell RNA-seq data
Patrick, R.; Humphreys, D. T.; Janbandhu, V.; Oshlack, A.; Ho, J. W. K.; Harvey, R. P.; Lo, K. K.
10.1101/867309 — bioinformatics — Posted on 2020-03-31
98 Telomere length and chromosomal instability for predicting individual radiosensitivity and risk via machine learning
Luxton, J. J.; McKenna, M. J.; Lewis, A. M.; Taylor, L. E.; Jhavar, S. G.; Swanson, G. P.; Bailey, S. M.
10.1101/2020.03.27.009043 — bioinformatics — Posted on 2020-03-31
99 Dissecting heterogeneous cell-populations across drug and disease conditions with PopAlign
Chen, S.; Park, J. H.; Tsou, T.; Rivaud, P.; Charles, E.; Haliburton, J.; Pichiorri, F.; Thomson, M.
10.1101/421354 — bioinformatics — Posted on 2020-03-31
100 Multiscale ATUM-FIB microscopy enables targeted ultrastructural analysis at isotropic resolution
Kislinger, G.; Gnaegi, H.; Kerschensteiner, M.; Simons, M.; Misgeld, T.; Schifferer, M.
10.1101/2020.03.30.015727 — neuroscience — Posted on 2020-03-31
104 Abundance and localization of human UBE3A protein isoforms
Sirois, C. L.; Bloom, J. E.; Fink, J. J.; Gorka, D.; Keller, S.; Germain, N. D.; Levine, E. S.; Chamberlain, S. J.
10.1101/2020.03.30.016857 — genetics — Posted on 2020-03-31
106 The role of historical contingency in shaping geographic pattern of deleterious mutation load in a broadly distributed Pacific Salmon
Rougemont, Q.; Moore, J.-S.; Leroy, T.; Normandeau, E.; Rondeau, E.; Withler, R.; Van Doornik, D.; Crane, P.; Naish, K.; Garza, J.-C.; Beacham, T. D.; Koop, B.; Bernatchez, L.
10.1101/732750 — evolutionary biology — Posted on 2020-03-31
110 Single-cell Bottlenecks and Dead-ends During Glioma Premalignancy
Sutcliffe, M.; Galvao, R.; Wang, L.; Kim, J.; Singh, S.; Zong, H.; Janes, K.
10.1101/2020.03.30.017228 — cancer biology — Posted on 2020-03-31
112 Generalization of the minimum covariance determinant algorithm for categorical and mixed data types
Beaton, D.; Sunderland, K. M.; ADNI, ; Levine, B.; Mandzia, J.; Masellis, M.; Swartz, R. H.; Troyer, A. K.; ONDRI, ; Binns, M. A.; Abdi, H.; Strother, S. C.
10.1101/333005 — bioinformatics — Posted on 2020-03-31
116 Allelic polymorphism shapes community function in evolving Pseudomonas aeruginosa populations
Azimi, S.; Roberts, A. E.; Peng, S.; Weitz, J. S.; McNally, A.; Brown, S. P.; Diggle, S. P.
10.1101/644724 — microbiology — Posted on 2020-03-31
121 Facilitative priority effects drive parasite assembly under coinfection
Halliday, F. W.; Penczykowski, R. M.; Barres, B.; Eck, J. L.; Numminen, E.; Laine, A.-L.
10.1101/2020.03.30.015495 — ecology — Posted on 2020-03-31
124 Nutritional inter-dependencies and a carbazole-dioxygenase are key elements of a bacterial consortium relying on a Sphingomonas for the degradation of the fungicide thiabendazol
Vasileiadis, S.; Perruchon, C.; Scheer, B.; Adrian, L.; Steinbach, N.; Trevisan, M.; Plaza-Bolanos, P.; Aguera, A.; Chatzinotas, A.; Karpouzas, D. G.
10.1101/2020.03.30.015693 — systems biology — Posted on 2020-03-31
125 Eco-evo-devo implications and archaeobiological perspectives of wild and domesticated grapevines fruits covariating traits
Bonhomme, V.; Picq, S.; Ivorra, S.; Evin, A.; Pastor, T.; Bacilieri, R.; Lacombe, T.; Figueiral, I.; Terral, J.-F.; Bouby, L.
10.1101/513036 — plant biology — Posted on 2020-03-31
126 Revealing the functions of supra-temporal and insular auditory responsive areas in humans
Wang, Q.; Luo, L.; Xu, N.; Wang, J.; Gao, Y.; Li, S.; Wang, M.; Teng, P.; Guan, Y.; Zhou, J.; Tian, X.; Luan, G.
10.1101/2020.03.30.015289 — neuroscience — Posted on 2020-03-31
127 A new mutant mouse model lacking mitochondrial-associated CB1 receptor
Pagano Zottola, A.; Soria-Gomez, E.; Bonilla-del-Rio, I.; Muguruza, C.; Terral, G.; Robin, L. M.; Oliveira da Cruz, J. F.; Redon, B.; Leste-Lassere, T.; Tolentino-Cortes, T.; Puente, N.; Barreda-Gomez, G.; Chaouloff, F.; Callado, L. F.; Grandes, P.; Marsicano, G.; Bellocchio, L.
10.1101/2020.03.30.009472 — neuroscience — Posted on 2020-03-31
131 Dopamine Signaling in the Dorsomedial Striatum Promotes Compulsive Behavior
Seiler, J. L.; Cosme, C. V.; Sherathiya, V. N.; Bianco, J. M.; Lerner, T. N.
10.1101/2020.03.30.016238 — neuroscience — Posted on 2020-03-31
132 HTCC as a highly effective polymeric inhibitor of SARS-CoV-2 and MERS-CoV
Milewska, A.; Chi, Y.; Szczepanski, A.; Barreto-Duran, E.; Liu, K.; Liu, D.; Guo, X.; Ge, Y.; Li, J.; Cui, L.; Ochman, M.; Urlik, M.; Rodziewicz-Motowidlo, S.; Zhu, F.; Szczubialka, K.; Nowakowska, M.; Pyrc, K.
10.1101/2020.03.29.014183 — microbiology — Posted on 2020-03-31
133 Combined prophylactic and therapeutic use maximizes hydroxychloroquine anti-SARS-CoV-2 effects in vitro
Clementi, N.; Criscuolo, E.; Diotti, R. A.; Ferrarese, R.; Castelli, M.; Burioni, R.; Clementi, M.; Mancini, N.
10.1101/2020.03.29.014407 — microbiology — Posted on 2020-03-31
135 Epitope-based chimeric peptide vaccine design against S, M and E proteins of SARS-CoV-2 etiologic agent of global pandemic COVID-19: an in silico approach
Rahman, M. S.; Hoque, M. N.; Islam, M. R.; Akter, S.; Rubayet-Ul-Alam, A. S. M.; Siddique, M. A.; Saha, O.; Rahaman, M. M.; Sultana, M.; Hossain, M. A.
10.1101/2020.03.30.015164 — microbiology — Posted on 2020-03-31
136 Potent neutralizing antibodies in the sera of convalescent COVID-19 patients are directed against conserved linear epitopes on the SARS-CoV-2 spike protein
Poh, C. M.; Carissimo, G.; Bei, W.; Amrun, S. N.; Lee, C. Y.-P.; Chee, R. S.-L.; Yeo, N. K.-W.; Lee, W.-H.; Leo, Y.-S.; Chen, M. I.-C.; Tan, S.-Y.; Chai, L. Y. A.; Kalimuddin, S.; Thien, S.-Y.; Young, B. E.; Lye, D. C.; Wang, C.-I.; Renia, L.; Ng, L. F.
10.1101/2020.03.30.015461 — immunology — Posted on 2020-03-31
137 Sequence analysis of SARS-CoV-2 genome reveals features important for vaccine design
Kames, J.; Holcomb, D. D.; Kimchi, O.; DiCuccio, M.; Hamasaki-Katagiri, N.; Wang, T.; Komar, A. A.; Alexaki, A.; Kimchi-Sarfaty, C.
10.1101/2020.03.30.016832 — bioinformatics — Posted on 2020-03-31
139 Fully human single-domain antibodies against SARS-CoV-2
Wu, Y.; Li, C.; Xia, S.; Tian, X.; Wang, Z.; Kong, Y.; Gu, C.; Zhang, R.; Tu, C.; Xie, Y.; Lu, L.; Jiang, S.; Ying, T.
10.1101/2020.03.30.015990 — microbiology — Posted on 2020-03-31
143 Lectin-like Intestinal Defensin Inhibits 2019-nCoV Spike binding to ACE2
Wang, C.; Wang, S.; Li, D.; Zhao, X.; Han, S.; Wang, T.; Zhao, G.; Chen, Y.; Chen, F.; Zhao, J.; Wang, L.; Sun, W.; Huang, Y.; Su, Y.; Wei, D.; Zhao, J.; Wang, J.
10.1101/2020.03.29.013490 — microbiology — Posted on 2020-03-31
145 Re-insights into origin and adaptation of SARS-CoV-2
Tagliamonte, M. S.; Adid, N.; Chillemi, G.; Salemi, M.; Mavian, C. N.
10.1101/2020.03.30.015685 — evolutionary biology — Posted on 2020-03-31
146 Structural analysis of SARS-CoV-2 andprediction of the human interactome
Vandelli, A.; Monti, M.; Milanetti, E.; Delli Ponti, R.; Tartaglia, G. G.
10.1101/2020.03.28.013789 — bioinformatics — Posted on 2020-03-31
147 Sequence variation among SARS-CoV-2 isolates in Taiwan
Gong, Y.-N.; Tsao, K.-C.; Hsiao, M.-J.; Huang, C.-G.; Huang, P.-N.; Huang, P.-W.; Lee, K.-M.; Liu, Y.-C.; Yang, S.-L.; Kuo, R.-L.; Liu, M.-T.; Yang, J.-R.; Chiu, C.-H.; Yang, C.-T.; Shih, S.-R.; Chen, G.-W.
10.1101/2020.03.29.014290 — genetics — Posted on 2020-03-31
149 Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic
Boni, M. F.; Lemey, P.; Jiang, X.; Lam, T. T.-Y.; Perry, B.; Castoe, T.; Rambaut, A.; Robertson, D. L.
10.1101/2020.03.30.015008 — evolutionary biology — Posted on 2020-03-31
151 In silico analysis of DNA re-replication across a complete genome reveals cell-to-cell heterogeneity and genome plasticity
Rapsomaniki, M. A.; Maxouri, S.; Ramirez Garrastacho, M.; Nathanailidou, P.; Giakoumakis, N. N.; Taraviras, S.; Lygeros, J.; Lygerou, Z.
10.1101/2020.03.30.016576 — systems biology — Posted on 2020-03-31
152 Overexpression of the chloroplastic 2-oxoglutarate/malate transporter in rice disturbs carbon and nitrogen homeostasis
Zamani Nour, S.; Lin, H.-C.; Walker, B. J.; Mettler-Altmann, T.; Khoshravesh, R.; Karki, S. P.; Bagunu, E. D.; Sage, T. L.; Quick, P.; Weber, A. P.
10.1101/2020.03.31.018226 — plant biology — Posted on 2020-03-31
156 Inhibition of the av integrin-TGF-b axis improves natural killer cell function against glioblastoma stem cells
Shaim, H.; Hernandez Sanabria, M.; Basar, R.; Wang, F.; Daher, M.; Zamler, D.; Gumin, J.; Gabrusiewicz, K.; Miao, Q.; Dou, J.; Alsuliman, A.; Kerbauy, L.; Acharya, S.; Mohanty, V.; Banerjee, P.; Mendt, M.; Li, S.; Lu, J.; Wei, J.; Fowlkes, N. W.; Gokdemir, E.; Ensley, E. L.; Kaplan, M.; Uprety, N.; Kassab, C.; Li, L.; Ozcan, G.; Shen, Y.; Gilbert, A. L.; Bdiwi, M.; Nunez Cortes, A. K.; Liu, E.; Yu, J.; Imahashi, N.; Muniz-Feliciano, L.; Hu, J.; Draetta, G.; Marin, D.; Yu, D.; Mielke, S.; Eyrich, M.; Champlin, R.; Chen, K.; Lang, F. F.; Shpall, E.; Heimberger, A.; Rezvani, K.
10.1101/2020.03.30.016667 — immunology — Posted on 2020-03-31
160 Rare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia
Bieder, A.; Einarsdottir, E.; Matsson, H.; Nilsson, H. E.; Eisfeldt, J.; Dragomir, A.; Paucar, M.; Granberg, T.; Li, T.-Q.; Lindstrand, A.; Kere, J.; Tapia-Paez, I.
10.1101/2020.03.30.011783 — genetics — Posted on 2020-03-31
162 Optoregulated force application to cellular receptors using molecular motors
Zheng, Y.; Han, M. K. L.; Zhao, R.; Blass, J.; Zhang, J.; Zhou, D. W.; Colard-Itte, J.-R.; Dattler, D.; Giuseppone, N.; Hoth, M.; Garcia, A. J.; Qu, B.; Bennewitz, R.; del Campo, A.
10.1101/2020.03.31.015198 — cell biology — Posted on 2020-03-31
166 SCHNEL: Scalable clustering of high dimensional single-cell data
Abdelaal, T.; de Raadt, P.; Lelieveldt, B. P. F.; Reinders, M. J. T.; Mahfouz, A.
10.1101/2020.03.30.015925 — bioinformatics — Posted on 2020-03-31
172 Mutual regulation between GDF11 and TET2 prevents senescence of mesenchymal stem cells
Gao, J.; Wang, H.; Shen, J.; Liu, X.; Zhu, X.; Zhao, E.; Li, G.; Sun, Y.; Yin, F.; Liu, Z.; Sun, Y. E.; Liu, H.
10.1101/2020.03.30.008722 — cell biology — Posted on 2020-03-31
176 Induction of hyperandrogenism and insulin resistance differentially modulates ferroptosis in uterine and placental tissues of pregnant rats
Zhang, Y.; Hu, M.; Jia, W.; Liu, G.; Zhang, J.; Wang, B.; Li, J.; Cui, P.; Li, X.; Lager, S.; Sferruzzi-Perri, A. N.; Han, Y.; Liu, S.; Wu, X.; Brannstrom, M.; Shao, L. R.; Billig, H.
10.1101/2020.03.30.015529 — physiology — Posted on 2020-03-31
181 CD8+ T-cell transcription and DNA methylation show age specific differences and lack correlation with clinical outcome in pediatric Inflammatory Bowel Disease
Gasparetto, M.; Payne, F.; Nayak, K.; Kraiczy, J.; Glemas, C.; Philip-McKenzie, Y.; Ross, A.; Edgar, R. D.; Zerbino, D.; Salvestrini, C.; Torrente, F.; Sarkies, P.; Heuschkel, R.; Zilbauer, M.
10.1101/2020.03.30.015446 — immunology — Posted on 2020-03-31
182 Molecular phylogeny of historical micro-invertebrate specimens using de novo sequence assembly
Orr, R. J. S.; Sannum, M. M.; Boessenkool, S.; Di Martino, E.; Gordon, D. P.; Mello, H.; Obst, M.; Ramsfjell, M. H.; Smith, A. M.; Liow, L. H.
10.1101/2020.03.30.015669 — evolutionary biology — Posted on 2020-03-31
183 On the accuracy of molecular simulation-based predictions of koff values: a Metadynamics study
Capelli, R.; Lyu, W.; Bolnykh, V.; Meloni, S.; Olsen, J. M. H.; Rothlisberger, U.; Parrinello, M.; Carloni, P.
10.1101/2020.03.30.015396 — biophysics — Posted on 2020-03-31
186 Dr AFC: Drug Repositioning Through Anti-Fibrosis Characteristic
Wu, D.; Gao, W.; Li, X.; Tian, C.; Jiao, N.; Fang, S.; Xiao, J.; Xu, Z.; Zhu, L.; Zhang, G.; Zhu, R.
10.1101/2020.03.30.015123 — bioinformatics — Posted on 2020-03-31
187 A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation
Yao, Z.; Nguyen, T. N.; van Velthoven, C. T. J.; Goldy, J.; Sedeno-Cortes, A. E.; Baftizadeh, F.; Bertagnolli, D.; Casper, T.; Crichton, K.; Ding, S.-L.; Fong, O.; Garren, E.; Glandon, A.; Gray, J.; Graybuck, L. T.; Hirschstein, D.; Kroll, M.; Lathia, K.; Levi, B.; McMillen, D.; Mok, S.; Pham, T.; Ren, Q.; Rimorin, C.; Shapovalova, N.; Sulc, J.; Sunkin, S. M.; Tieu, M.; Torkelson, A.; Tung, H.; Ward, K.; Dee, N.; Smith, K. A.; Tasic, B.; Zeng, H.
10.1101/2020.03.30.015214 — neuroscience — Posted on 2020-03-31
188 Essential roles of plexin-B3+ oligodendrocyte precursor cells in the pathogenesis of Alzheimer's disease
Nihonmatsu-Kikuchi, N.; Yu, X.-J.; Matsuda, Y.; Ozawa, N.; Ito, T.; Satou, K.; Kaname, T.; Takashima, A.; Toru, S.; Hirokawa, K.; Hasegawa, M.; Uchihara, T.; Tatebayashi, Y.
10.1101/2020.03.30.015297 — neuroscience — Posted on 2020-03-31
189 Folliculin variants linked to Birt-Hogg-Dube syndrome are targeted for proteasomal degradation
Clausen, L.; Stein, A.; Gronbaek-Thygesen, M.; Nygaard, L.; Soltoft, C. L.; Nielsen, S. V.; Lisby, M.; Ravid, T.; Lindorff-Larsen, K.; Hartmann-Petersen, R.
10.1101/2020.03.30.015248 — molecular biology — Posted on 2020-03-31
191 Loss of mutant TP53 does not impair the sustained proliferation, survival ormetastasis of diverse cancer cells
Wang, Z.; Vailllant, F.; Chang, C.; Riffkin, C.; Lieschke, E.; Diepstraten, S.; Huang, D.; Visvader, J. E.; Herold, M. J.; Kelly, G.; Strasser, A.
10.1101/2020.03.30.015263 — cancer biology — Posted on 2020-03-31
201 Uptake of endogenous serine is important to maintain sphingolipid homeostasis in Saccharomyces cerevisiae
Fröhlich, F.; Esch, B. M.; Limar, S.; Bogdanowski, A.; Gournas, C.; More, T.; Sundag, C.; Walter, S.; Heinisch, J. J.; Ejsing, C. S.; Andre, B.
10.1101/2020.03.30.016220 — genetics — Posted on 2020-03-30
203 The Regulation of Developmental Diapause is Coordinated with Molting and Olfaction
Carstensen, H. R.; Villalon, R.; Vertiz, J.; Banerjee, N.; Hallem, E. A.; Hong, R. L.
10.1101/2020.03.30.016311 — developmental biology — Posted on 2020-03-30
206 HIV-1 promoter is gradually silenced when integrated into BACH2
Inderbitzin, A.; Kok, Y. L.; Jörimann, L.; Kelley, A.; Neumann, K.; Heinzer, D.; Cathomen, T.; Metzner, K. J.
10.1101/2020.03.30.011395 — microbiology — Posted on 2020-03-30
212 SARS-CoV-2 receptor ACE2 and TMPRSS2 are predominantly expressed in a transient secretory cell type in subsegmental bronchial branches
Lukassen, S.; Chua, R. L.; Trefzer, T.; Kahn, N. C.; Schneider, M. A.; Muley, T.; Winter, H.; Meister, M.; Veith, C.; Boots, A. W.; Hennig, B. P.; Kreuter, M.; Conrad, C.; Eils, R.
10.1101/2020.03.13.991455 — genomics — Posted on 2020-03-30
213 The drought-responsive ZmFDL1 gene regulates cuticle biosynthesis and cuticle-dependent leaf permeability
Castorina, G.; Domergue, F.; Chiara, M.; Zilio, M.; Persico, M.; Ricciardi, V.; Horner, D. S.; Consonni, G.
10.1101/2020.03.30.014332 — plant biology — Posted on 2020-03-30
216 Interpretative guides for interacting with tissue atlas and digital pathology data using the Minerva browser
Rashid, R.; Chen, Y.-A.; Hoffer, J.; Muhlich, J. L.; Lin, J.-R.; Krueger, R.; Pfister, H.; Mitchell, R.; Santagata, S.; Sorger, P.
10.1101/2020.03.27.001834 — scientific communication and education — Posted on 2020-03-30
221 Inhibition of mTOR during a postnatal sensitive window rescues deficits in GABAergic PV cell connectivity and social behavior caused by loss of TSC1.
Choudhury, M.; Amegandjin, C. A.; Jadhav, V.; Nunes-Carrico, J.; Quintal, A.; Berryer, M.; Snapyan, M.; Chattopadhyaya, B.; Saghatelyan, A.; Di Cristo, G.
10.1101/2020.03.29.014563 — neuroscience — Posted on 2020-03-30
222 Alzheimer's disease risk gene BIN1 induces Tau-dependent network hyperexcitability
Voskobiynyk, Y.; Roth, J. R.; Cochran, J. N.; Rush, T.; Carullo, N. V. N.; Mesina, J. S.; Waqas, M.; Vollmer, R. M.; Day, J. J.; McMahon, L. L.; Roberson, E. D.
10.1101/2020.03.29.014720 — neuroscience — Posted on 2020-03-30
225 Ocular conjunctival inoculation of SARS-CoV-2 can cause mild COVID-19 in Rhesus macaques
Deng, W.; Bao, L.; Gao, H.; Xiang, Z.; Qu, Y.; Song, Z.; Gong, S.; Liu, J.; Liu, J.; Yu, P.; Qi, F.; Xu, Y.; Li, F.; Xiao, C.; Lv, Q.; Xue, J.; Wei, Q.; Liu, M.; Wang, G.; Wang, S.; Yu, H.; Liu, X.; Zhao, W.; Han, Y.; Qin, C.
10.1101/2020.03.13.990036 — microbiology — Posted on 2020-03-30
229 Cardio-centric hemodynamic management improves spinal cord oxygenation and mitigates hemorrhage in acute spinal cord injury
Williams, A. M.; Manouchehri, N.; Erskine, E.; Tauh, K.; So, K.; Streijger, F.; Shortt, K.; Kim, K.-T.; Kwon, B. K.; West, C. R.
10.1101/2020.03.29.014498 — neuroscience — Posted on 2020-03-30
231 In vivo photopharmacology enabled by multifunctional fibers
Frank, J. A.; Antonini, M.-J.; Chiang, P.-H.; Canales, A.; Konrad, D.; Garwood, I.; Rajic, G.; Koehler, F.; Fink, Y.; Anikeeva, P.
10.1101/2020.03.28.012567 — neuroscience — Posted on 2020-03-30
236 MORFEE: a new tool for detecting and annotating single nucleotide variants creating premature ATG codons from VCF files
Aissi, D.; Soukarieh, O.; Proust, C.; Jaspard-Vinassa, B.; Fautrad, P.; Ibrahim-Kosta, M.; Leal-Valentim, F.; Roux, M.; Bacq-Daian, D.; Olaso, R.; Deleuze, J.-F.; Morange, P.-E.; Tregouet, D.-A.
10.1101/2020.03.29.012054 — bioinformatics — Posted on 2020-03-30
239 Human keratinocyte (HaCaT) stimulation and healing effect of the methanol fraction from the decoction from leaf from Sideroxylon obtusifolium (Roem. & Schult.) T.D. Penn on experimental burn wound model
Souza, T. d. F. G. d.; Pierdona, T. M.; Macedo, F. S.; de Aquino, P. E. A.; Rangel, G. d. F. P.; Duarte, R. S.; Viana, G. S. d. B.; Alves, A. P. N. N.; Montenegro, R. C.; Wilke, D. V.; Silveira, E. R.; Alencar, N. M. N. d.
10.1101/2020.03.29.013839 — pharmacology and toxicology — Posted on 2020-03-30
240 CIS checkpoint deletion enhances the fitness of cord blood derived natural killer cells transduced with a chimeric antigen receptor
Rezvani, K.; Daher, M.; Basar, R.; Gokdemir, E.; Baran, N.; Uprety, N.; Mendt, M.; Kerbauy, L.; Hernandez Sanabria, M.; Imahashi, N.; Nunez, A.; Li, L.; Fathi, M.; Rezvan, A.; Mohanty, V.; Banerjee, P.; Shaim, H.; Lu, J.; Ozcan, G.; Ensley, E.; Kaplan, M.; Nandivada, V.; Xi, Y.; Mak, D.; Liu, E.; Ang, S.; Muniz-Feliciano, L.; Wang, J.; Kordasti, S.; Petrov, N.; Varadarajan, N.; Marin, D.; Brunetti, L.; Skinner, R.; Lyu, S.; Silva, L.; Schubert, M.; Rettig, G.; Turk, R.; Behlke, M.; McNeill, M. S.; Kurgan, G.; Fowlkes, N. W.; Li, H.; Chen, K.; Konopleva, M.; Champlin, R.; Shpall, E. J.; Wei Inn
10.1101/2020.03.29.014472 — immunology — Posted on 2020-03-30
242 Orthogonal genome-wide screenings in bat cells identify MTHFD1 as a target of broad antiviral therapy
Anderson, D. E.; Cui, J.; Ye, Q.; Huang, B.; Zu, W.; Gong, J.; Liu, W.; Kim, S. Y.; Yan, B. G.; Sigmundsson, K.; Lim, X. F.; Ye, F.; Niu, P.; Zhou, X.; Tan, W.; Wang, L.-F.; Tan, X.
10.1101/2020.03.29.014209 — microbiology — Posted on 2020-03-30
243 A Histoplasma capsulatum lipid metabolic map identifies antifungal targets and virulence factors
Zamith-Miranda, D.; Heyman, H. M.; Burnet, M. C.; Couvillion, S. P.; Zheng, X.; Munoz, N.; Kyle, J. E.; Zink, E. M.; Weitz, K. K.; Bloodsworth, K. J.; Clair, G. C.; Zucker, J. D.; Teuton, J. R.; Payne, S. H.; Kim, Y.-M.; Reyes Gil, M.; Baker, E. S.; Bredeweg, E. L.; Nosanchuk, J. D.; Nakayasu, E. S.
10.1101/2020.03.02.973412 — microbiology — Posted on 2020-03-30
244 SARS-CoV-2 detection from nasopharyngeal swab samples without RNA extraction
Beltran-Pavez, C.; Marquez, C. L.; Munoz, G.; Valiente-Echeverria, F.; Gaggero, A.; Soto-Rifo, R.; Barriga, G. P.
10.1101/2020.03.28.013508 — molecular biology — Posted on 2020-03-30
245 Functional connectivity changes with rapid remission from severe major depressive disorder
Xiao, X.; Bentzley, B.; Cole, E. J.; Tischler, C.; Stimpson, K. H.; Duvio, D.; Bishop, J. H.; DeSouza, D. D.; Schatzberg, A.; Keller, C.; Sudheimer, K.; Williams, N. R.
10.1101/672154 — clinical trials — Posted on 2020-03-30
246 Framing the potential of public frameshift peptides as immunotherapy targets in colon cancer
Spaanderman, I. T.; Peters, F. S.; Jongejan, A.; Redeker, E. J.; Punt, C. J. A.; Bins, A. D.
10.1101/2020.03.26.010231 — cancer biology — Posted on 2020-03-30
248 Noncoding regions underpin avian bill shape diversification at macroevolutionary scales
Yusuf, L.; Heatley, M. C.; Palmer, J. P.; Barton, H. J.; Cooney, C. R.; Gossmann, T. I.
10.1101/844951 — evolutionary biology — Posted on 2020-03-30
249 Improving replicability in single-cell RNA-Seq cell type discovery with Dune
Roux de Bezieux, H.; Street, K.; Fischer, S.; Van den Berge, K.; Chance, R.; Risso, D.; Gillis, J.; Ngai, J.; Purdom, E.; Dudoit, S.
10.1101/2020.03.03.974220 — bioinformatics — Posted on 2020-03-30
250 Comparative Genomic Analysis of Rapidly Evolving SARS CoV-2 Viruses Reveal Mosaic Pattern of Phylogeographical Distribution
Kumar, R.; Verma, H.; Singhvi, N.; Sood, U.; Gupta, V.; Singh, M.; Sharma, R.; Hira, P.; Nagar, S.; Talwar, C.; Nayyar, N.; Anand, S.; Rawat, C. D.; Verma, M.; Negi, R. K.; Singh, Y.; Lal, R.
10.1101/2020.03.25.006213 — microbiology — Posted on 2020-03-30
251 SCITO-seq: single-cell combinatorial indexed cytometry sequencing
Hwang, B.; Lee, D. S.; Tamaki, W.; Sun, Y.; Ogorodnikov, A.; Hartoularos, G.; Winters, A.; Song, Y. S.; Chow, E. D.; Spitzer, M. H.; Ye, C. J.
10.1101/2020.03.27.012633 — genomics — Posted on 2020-03-30
253 Multimodal brain imaging study of 19,825 participants reveals adverse effects of moderate drinking
Daviet, R.; Aydogan, G.; Jagannathan, K.; Spilka, N.; Koellinger, P.; Kranzler, H. R.; Nave, G.; Wetherill, R.
10.1101/2020.03.27.011791 — neuroscience — Posted on 2020-03-30
257 Renewable Fatty Acid Ester Production in Clostridium
Feng, J.; Zhang, J.; Wang, P.; Jimenez-Bonilla, P.; Gu, Y.; Zhou, J.; Cao, M.; Shao, Z.; Borovok, I.; Wang, Y.
10.1101/2020.03.29.014746 — bioengineering — Posted on 2020-03-30
266 NAD+ prevents septic shock by non-canonical inflammasome blockade and IL-10
Iske, J.; EL Fatimy, R.; Nian, Y.; Eskandari, S.; Rodriguez Cetina Biefer, H.; Vasudevan, A.; Elkhal, A.
10.1101/2020.03.29.013649 — immunology — Posted on 2020-03-30
270 Antimicrobial peptide induced-stress renders Staphylococcus aureus susceptible to toxic nucleoside analogues
Rodriguez-Rojas, A.; Nath, A.; El Shazely, B.; Santi, G.; Kim, J. J.; Kuropka, B.; Weise, C.; Rolff, J.
10.1101/2020.03.30.015206 — microbiology — Posted on 2020-03-30
271 Non-retroviral endogenous viral element limits cognate virus replication in Aedes aegypti ovaries
Suzuki, Y.; Baidaliuk, A.; Miesen, P.; Frangeul, L.; Crist, A. B.; Merkling, S. H.; Fontaine, A.; Lequime, S.; Moltini-Conclois, I.; Blanc, H.; van Rij, R. P.; Lambrechts, L.; Saleh, M.-C.
10.1101/2020.03.28.013441 — microbiology — Posted on 2020-03-30
272 Subtilase activity in the intrusive cells mediates haustorium maturation in parasitic plants
Ogawa, S.; Wakatake, T.; Spallek, T.; Ishida, J. K.; Sano, R.; Kurata, T.; Demura, T.; Yoshida, S.; Ichihashi, Y.; Schaller, A.; Shirasu, K.
10.1101/2020.03.30.015149 — plant biology — Posted on 2020-03-30
273 Host-parasite tissue adhesion by a secreted type of β-1,4-glucanase in the parasitic plant Phtheirospermum japonicum
Kurotani, K.-i.; Wakatake, T.; Ichihashi, Y.; Okayasu, K.; Sawai, Y.; Ogawa, S.; Suzuki, T.; Shirasu, K.; Notaguchi, M.
10.1101/2020.03.29.014886 — plant biology — Posted on 2020-03-30
275 How well do crop modeling groups predict wheat phenology, given calibration data from the target population?
Wallach, D.; Palosuo, T.; Thorburn, P.; Gourdain, E.; Asseng, S.; Basso, B.; Buis, S.; Crout, N.; Dibari, C.; Dumont, B.; Ferrise, R.; Gaiser, T.; Garcia, C.; Gayler, S.; Ghahramani, A.; Hochman, Z.; Hoek, S.; Horan, H.; Hoogenboom, G.; Huang, M.; Jabloun, M.; Jing, Q.; Justes, E.; Kersebaum, K. C.; Klosterhalfen, A.; Launay, M.; Luo, Q.; Maestrini, B.; Mielenz, H.; Moriondo, M.; Nariman Zadeh, H.; Olesen, J. E.; Poyda, A.; Priesack, E.; Pullens, J. W. M.; Budong, Q.; Schuetze, N.; Shelia, V.; Souissi, A.; Specka, X.; Srivastava, A. K.; Stella, T.; Streck, T.; Trombi, G.; Wallor, E.; Wang, J.;
10.1101/708578 — plant biology — Posted on 2020-03-30
276 A novel antiviral formulation inhibits a range of enveloped viruses.
Fletcher, N. F.; Meredith, L. W.; Tidswell, E. L.; Bryden, S. R.; Goncalves-Carneiro, D.; Chaudhry, Y.; Shannon-Lowe, C.; Folan, M. A.; Lefteri, D. A.; Pingen, M.; Bailey, D.; McKimmie, C. S.; Baird, A. W.
10.1101/2020.03.29.009464 — microbiology — Posted on 2020-03-30
281 Ibrutinib blocks YAP1 activation and reverses BRAFi resistance in melanoma cells
Misek, S. A.; Newbury, P. A.; Chekalin, E.; Paithankar, S.; Doseff, A. I.; Chen, B.; Gallo, K. A.; Neubig, R. R.
10.1101/2020.03.25.006916 — cancer biology — Posted on 2020-03-30
282 Telomere length and chromosomal instability for predicting individual radiosensitivity and risk via machine learning
Luxton, J. J.; McKenna, M. J.; Lewis, A. M.; Taylor, L. E.; Jhavar, S. G.; Swanson, G. P.; Bailey, S. M.
10.1101/2020.03.27.009043 — bioinformatics — Posted on 2020-03-30
287 A single-cell and single-nucleus RNA-seq toolbox for fresh and frozen human tumors
Slyper, M.; Porter, C. B. M.; Ashenberg, O.; Waldman, J.; Drokhlyansky, E.; Wakiro, I.; Smillie, C.; Smith-Rosario, G.; Wu, J.; Dionne, D.; Vigneau, S.; Jane-Valbuena, J.; Napolitano, S.; Su, M.-J.; Patel, A. G.; Karlstrom, A.; Gritsch, S.; Nomura, M.; Waghray, A.; Gohil, S. H.; Tsankov, A. M.; Jerby-Arnon, L.; Cohen, O.; Klughammer, J.; Rosen, Y.; Gould, J.; Li, B.; Nguyen, L.; Wu, C. J.; Izar, B.; Haq, R.; Hodi, F. S.; Yoon, C. H.; Hata, A. N.; Baker, S. J.; Suva, M. L.; Bueno, R.; Stover, E. H.; Matulonis, U. A.; Clay, M. R.; Dyer, M. A.; Collins, N. B.; Wagle, N.; Rotem, A.; Johnson, B. E.
10.1101/761429 — genomics — Posted on 2020-03-30
288 The HPA stress axis shapes aging rates in long-lived, social mole-rats
Sahm, A.; Hoffmann, S.; Koch, P.; Henning, Y.; Bens, M.; Groth, M.; Burda, H.; Begall, S.; Ting, S.; Goetz, M.; Van Daele, P.; Staniszewska, M.; Klose, J.; Costa, P. F.; Platzer, M.; Szafranski, K.; Dammann, P.
10.1101/2020.02.22.961011 — genomics — Posted on 2020-03-30
289 Disease-specific variant pathogenicity prediction significantly improves variant interpretation in inherited cardiac conditions
Zhang, X.; Walsh, R.; Whiffin, N.; Buchan, R.; Midwinter, W.; Wilk, A.; Govind, R.; Li, N.; Ahmad, M.; Mazzarotto, F.; Roberts, A.; Theotokis, P.; Mazaika, E.; Allouba, M.; de Marvao, A.; Pua, C. J.; Day, S. M.; Ashley, E.; Colan, S. D.; Michels, M.; Pereira, A. C.; Jacoby, D.; Ho, C. Y.; Olivotto, I.; Gunnarsson, G. T.; Jefferies, J.; Semsarian, C.; Ingles, J.; O'Regan, D. P.; Aguib, Y.; Yacoub, M. H.; Cook, S.; Barton, P. J. R.; Bottolo, L.; Ware, J. S.
10.1101/2020.03.27.010736 — genetics — Posted on 2020-03-30
292 Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL
Sloan, J.; Hankenjos, J.; Gebert, M.; Ermakova, O.; Gumiero, A.; Stier, G.; Wild, K.; Sinning, I.; Lohmann, J. U.
10.1101/2020.03.26.009761 — plant biology — Posted on 2020-03-30
293 Motor planning modulates neural activity patterns in early human auditory cortex
Gale, D. J.; Areshenkoff, C. N.; Honda, C. T.; Johnsrude, I. S.; Flanagan, J. R.; Gallivan, J. P.
10.1101/682609 — neuroscience — Posted on 2020-03-30
294 Distinct Regulation of Bioenergetics and Translation by Gp I mGluR and NMDAR
Ghosh Dastidar, S.; Sharma, S. D.; Chakraborty, S.; Chattarji, S.; Bhattacharya, A.; Muddashetty, R.
10.1101/552638 — neuroscience — Posted on 2020-03-30
296 Isolation and characterization of two bacterial strains from textile effluents having Malachite Green dye degradation ability
Roy, D. C.; Sheam, M. M.; Hasan, M. R.; Saha, A. K.; Roy, A. K.; Haque, M. E.; Rahman, M. M.; Swee-Seong, T.; Biswas, S. K.
10.1101/2020.03.29.014274 — microbiology — Posted on 2020-03-30
299 Genetically encoded live cell sensor for tyrosinated microtubules
Kesarwani, S.; Lama, P.; Chandra, A.; Reddy, P. P.; Jijumon, A.; Bodakuntla, S.; Rao, B. M.; Janke, C.; Das, R.; Sirajuddin, M.
10.1101/2020.03.29.013250 — cell biology — Posted on 2020-03-30
300 Misoprostol Attenuates Cardiomyocyte Proliferation in the Neonatal Heart Through Bnip3 and Perinuclear Calcium Signaling
Martens, M. D.; Field, J. T.; Seshadri, N.; Day, C.; Chapman, D.; Keijzer, R.; Doucette, C. R.; Hatch, G. M.; West, A. R.; Ivanco, T. L.; Gordon, J. W.
10.1101/681692 — cell biology — Posted on 2020-03-30
301 De novo reconstruction of microbial haplotypes by integrating statistical and physical linkage
cao, c.; he, j.; mak, l.; Perera, D.; Kwok, D.; Wang, J.; Li, M.; Mourier, T.; Gavriliuc, S.; Greenberg, M.; Morrissy, S.; Sycuro, L.; yang, g.; Jeffares, D. C.; Long, Q.
10.1101/2020.03.29.014704 — bioinformatics — Posted on 2020-03-30
304 Cell-free biogenesis of bacterial division proto-rings that can constrict liposomes
Godino, E.; Noguera Lopez, J.; Zarguit, I.; Doerr, A.; Jimenez, M.; Rivas, G.; Danelon, C.
10.1101/2020.03.29.009639 — synthetic biology — Posted on 2020-03-30
307 DNA methylation classification in diffuse glioma shows little spatial heterogeneity after adjusting for tumor purity
Verburg, N.; Barthel, F. P.; Anderson, K. J.; Johnson, K. C.; Koopman, M.; Yaqub, M.; Hoekstra, O.; Lammertsma, A.; Barkhof, F.; Pouwels, P.; Reijneveld, J. C.; Rozemuller, A.; Boellaard, R.; Taylor, M. D.; Das, S.; Costello, J. F.; Vandertop, W. P.; Wesseling, P.; De Witt Hamer, P. C.; Verhaak, R. G.
10.1101/2020.03.28.012732 — cancer biology — Posted on 2020-03-29
311 Dynamic inhibition of sensory responses mediated by an olfactory corticofugal system
Medinaceli Quintela, R.; Bauer, J.; Wallhorn, L.; Brunert, D.; Rothermel, M.
10.1101/2020.03.29.014571 — neuroscience — Posted on 2020-03-29
312 Estrogen and sex-dependent loss of the vocal learning system in female zebra finches
Choe, H. N.; Tewari, J.; Zhu, K. W.; Davenport, M.; Matsunami, H.; Jarvis, E. D.
10.1101/2020.03.28.011932 — neuroscience — Posted on 2020-03-29
313 Monitoring phagocytic uptake of amyloid β into glial cell lysosomes in real time
Prakash, P.; Jethava, K. P.; Korte, N.; Izquierdo, P.; Favuzzi, E.; Rose, I.; Guttenplan, K. A.; Dutta, S.; Rochet, C.; Fishell, G.; Liddelow, S.; Attwell, D.; Chopra, G.
10.1101/2020.03.29.002857 — neuroscience — Posted on 2020-03-29
314 Knowledge synthesis from 100 million biomedical documents augments the deep expression profiling of coronavirus receptors
Venkatakrishnan, A.; Puranik, A.; Anand, A.; Zemmour, D.; Yao, X.; Wu, X.; Chilaka, R.; Murakowski, D. K.; Standish, K.; Raghunathan, B.; Wagner, T.; Garcia-Rivera, E.; Solomon, H.; Garg, A.; Barve, R.; Anyanwu-Ofili, A.; Khan, N.; Soundararajan, V.
10.1101/2020.03.24.005702 — genomics — Posted on 2020-03-29
315 CReSCENT: CanceR Single Cell ExpressioN Toolkit
Mohanraj, S.; Diaz-Mejia, J. J.; Pham, M.; Elrick, H.; Husic, M.; Rashid, S.; Luo, P.; Bal, P.; Lu, K.; Patel, S.; Mahalanabis, A.; Naidas, A.; Christensen, E.; Croucher, D.; Richards, L.; Shooshtari, P.; Brudno, M.; Ramani, A.; Pugh, T. J.
10.1101/2020.03.27.012740 — bioinformatics — Posted on 2020-03-29
317 Durable Changes to Airway Mucus and Fluid Secretion Following Cholinergic Challenge
Liao, Y.-S. J.; Collins, E. N.; Guevara, M. V.; Schurmann, V.; Atanasova, K. R.; Bravo, L.; Sponchiado, M.; Hoegger, M. J.; Reznikov, L. R.
10.1101/2020.03.27.012575 — physiology — Posted on 2020-03-29
318 Inhalation: A means to explore and optimize nintedanib's pharmacokinetic/pharmacodynamic relationship
Epstein-Shochet, G.; Pham, S.; Beck, S.; Naiel, S.; Mekhael, O.; Revill, S.; Hayat, A.; Vierhout, M.; Bardestein-Wald, B.; Shitrit, D.; Ask, K.; Montgomery, A. B.; Kolb, M.; Surber, M.
10.1101/2020.03.27.012401 — pharmacology and toxicology — Posted on 2020-03-29
322 Brain structures associated with reading and their abnormalities in dyslexia: a wholebrainanalysis
Kujala, T.; Thiede, A.; Palo-oja, P.; Virtala, P.; Laasonen, M.; Numminen, J.; Sihvonen, A. J.
10.1101/2020.03.27.011577 — neuroscience — Posted on 2020-03-29
323 Anthrax Toxin as a Molecular Platform to Target Nociceptive Neurons and Modulate Pain
Yang, N. J.; Isensee, J.; Neel, D.; Liu, S. M.; Zhang, H. X. B.; Belu, A.; Palan, S.; Kennedy-Curran, A.; Röderer, P.; Nitzsche, A.; Lu, M.; Pentelute, B. L.; Brüstle, O.; Tripathi, V.; Park, J. M.; Collier, R. J.; Foster, K. A.; Bean, B. P.; Leppla, S. H.; Hucho, T.; Chiu, I. M.
10.1101/2020.03.28.004150 — neuroscience — Posted on 2020-03-29
324 In Vivo Localization of Deep Brain Implants in Mice
Kiraly, B.; Balazsfi, D.; Horvath, I.; Solari, N.; Sviatko, K.; Lengyel, K.; Birtalan, E.; Mathe, D.; Szigeti, K.; Hangya, B.
10.1101/2020.03.28.011858 — neuroscience — Posted on 2020-03-29
327 Telomere length and chromosomal instability for predicting individual radiosensitivity and risk via machine learning
Luxton, J. J.; McKenna, M. J.; Lewis, A. M.; Taylor, L. E.; Jhavar, S. G.; Swanson, G. P.; Bailey, S. M.
10.1101/2020.03.27.009043 — bioinformatics — Posted on 2020-03-29
329 Integrating spatial capture-recapture models with variable individual identifiability
Ruprecht, J.; Eriksson, C.; Forrester, T. D.; Clark, D. A.; Wisdom, M.; Rowland, M. M.; Johnson, B. K.; Levi, T.
10.1101/2020.03.27.010850 — ecology — Posted on 2020-03-29
334 What and When Local Predictors Drive Tadpole Diversity in Subtropical Temporary Ponds?
Dalmolin, D. A.; dos Santos, T. G.; Tozetti, A. M.; Ramos Pereira, M. J. V. d. C.
10.1101/2020.03.27.978338 — ecology — Posted on 2020-03-29
335 Framing the potential of public frameshift peptides as immunotherapy targets in colon cancer
Spaanderman, I. T.; Peters, F. S.; Jongejan, A.; Redeker, E. J.; Punt, C. J. A.; Bins, A. D.
10.1101/2020.03.26.010231 — cancer biology — Posted on 2020-03-29
337 Tracing the in vivo fate of nanoparticles with a "non-self" biological identity
Mohammad-Beigi, H.; Scavenius, C.; Jensen, P. B.; Kjaer-Sorensen, K.; Oxvig, C.; Boesen, T.; Enghild, J. J.; Sutherland, D. S.; Hayashi, Y.
10.1101/2020.03.27.012146 — pharmacology and toxicology — Posted on 2020-03-29
339 Prion protein lowering is a disease-modifying therapy across prion strains, disease stages, and endpoints
Minikel, E. V.; Zhao, H. T.; Le, J.; O'Moore, J.; Pitstick, R.; Graffam, S.; Carlson, G. A.; Kriz, J.; Kim, J. B.; Ma, J.; Wille, H.; Aiken, J.; McKenzie, D.; Doh-ura, K.; Beck, M.; O'Keefe, R.; Stathopoulos, J.; Caron, T.; Schreiber, S. L.; Carroll, J. B.; Kordasiewicz, H. B.; Cabin, D. E.; Vallabh, S. M.
10.1101/2020.03.27.011940 — neuroscience — Posted on 2020-03-29
348 A two-stage ECG signal denoising method based on deep convolutional network
Qiu, L.; Cai, W.; Yu, J.; Zhong, J.; Wang, Y.; Li, W.; Chen, Y.; Wang, L.
10.1101/2020.03.27.012831 — bioengineering — Posted on 2020-03-29
351 Quantifying myelin content in brain tissue using color spatial light interference microscopy (cSLIM)
Popescu, G.; Caputo, M.; Lee, Y.-J.; Rund, L.; Best, C.; Kandel, M.; Johnson, R.; Das, T.; Kuchan, M.; Fanous, M.
10.1101/2020.03.27.012229 — neuroscience — Posted on 2020-03-29
353 Comparative performance of four nucleic acid amplification tests for SARS-CoV-2 virus
Xiong, Y.; Li, Z.-Z.; Zhuang, Q.; Chao, Y.; Li, F.; Ge, Y.-Y.; Wang, Y.; Ke, P.-F.; Huang, X.
10.1101/2020.03.26.010975 — molecular biology — Posted on 2020-03-29
356 A systematic, unbiased mapping of CD8+ and CD4+ T cell epitopes in Yellow Fever vaccinees
Stryhn, A.; Kongsgaard, M.; Rasmussen, M.; Harndahl, M. N.; Osterbye, T.; Bassi, M. R.; Thybo, S.; Gabriel, M.; Hansen, M. B.; Nielsen, M.; Christensen, J. P.; Thomsen, A. R.; Buus, S.
10.1101/2020.03.28.012468 — immunology — Posted on 2020-03-29
357 A novel full-reduced HMGB1 and kartogenin-containing bio-active scaffold for meniscus regeneration
Xu, H.; Dai, Z.; Zou, X.; Xia, P.; ABOUDI, M. A.; Wang, J.; Lam Sung Foon, W. A.; Huang, H.
10.1101/2020.03.26.010108 — bioengineering — Posted on 2020-03-29
359 Soybean Yellow Stripe-like7 is a symbiosome membrane peptide transporter essential for nitrogen fixation
Gavrin, A.; Loughlin, P. C.; Brear, E.; Griffith, O. W.; Bedon, F.; Suter Grotemeyer, M.; Escudero, V.; Reguera, M.; Qu, Y.; Mohd-Noor, S. N.; Chen, C.; Orsorio, M. B.; Rentsch, D.; Gonzalez-Guerrero, M.; Day, D. A.; Smith, P. M. C.
10.1101/2020.03.27.011973 — plant biology — Posted on 2020-03-29
365 Antimicrobial Resistance Profile and mcr-1 gene Detection in Salmonella Isolates from Poultry in Bangladesh: Molecular and Bioinformatics Characterization
Uddin, M. B.; Hossain, S. B.; Hasan, M.; Alam, M. N.; Debnath, M.; Begum, R.; Roy, S.; Harun-Al-Rashid, A.; Chowdhury, M. S. R.; Rahman, M. M.; Hossain, M. M.; Chowdhury, M. Y. E.; Ahmed, S. S. U.
10.1101/2020.03.27.012948 — microbiology — Posted on 2020-03-29
366 Bifidobacterium breve UCC2003 induces a distinct global transcriptomic programme in neonatal murine intestinal epithelial cells
Kiu, R.; Treveil, A.; Harnisch, L. C.; Caim, S.; Leclaire, C.; van Sinderen, D.; Korcsmaros, T.; Hall, L. J.
10.1101/2020.03.27.011692 — immunology — Posted on 2020-03-29
367 Brain capillary pericytes exert a substantial but slow influence on blood flow
Hartmann, D. A.; Berthiaume, A.-A.; Grant, R. I.; Harill, S. A.; Noonan, T.; Costello, J.; Tieu, T.; McDowell, K.; Faino, A.; Kelly, A.; Shih, A. Y.
10.1101/2020.03.26.008763 — neuroscience — Posted on 2020-03-29
369 Behavioral, physiological, and neural signatures of surprise during naturalistic sports viewing
Antony, J. W.; Hartshorne, T. H.; Pomeroy, K.; Gureckis, T. M.; Hasson, U.; McDougle, S. D.; Norman, K. A.
10.1101/2020.03.26.008714 — neuroscience — Posted on 2020-03-29
371 Purine metabolism regulates DNA repair and therapy resistance in glioblastoma
Zhou, W.; Yao, Y.; Scott, A. J.; Romans, K. W.; Dresser, J. J.; Werner, C. K.; Sun, H.; Pratt, D.; Sajjakulnukit, P.; Zhao, S. G.; Davis, M.; Morgan, M. A.; Rehemtualla, A.; Nelson, B. S.; Halbrook, C. J.; Zhang, L.; Gatto, F.; Xiong, J.; Castro, M.; Lowenstein, P. R.; Chandrasekaran, S.; Lawrence, T. S.; Lyssiotis, C. A.; Wahl, D. R.
10.1101/2020.03.26.010140 — neuroscience — Posted on 2020-03-29
373 Shared and distinct patterns of atypical cortical morphometry in children with autism and anxiety
Yin, S.; Hong, S.-J.; Di Martino, A.; Milham, M.; Park, B.-Y.; Benkarim, O.; Bethlehem, R. A. I.; Bernhardt, B.; Paquola, C.
10.1101/2020.03.26.010272 — neuroscience — Posted on 2020-03-29
375 Hypoxic gene expression in chronic hepatitis B infected patients is not observed in state-of-art in vitro and mouse infection models
Liu, P. J.; Harris, J. M.; Marchi, E.; D'Arienzo, V.; Michler, T.; Wing, P. A.; Magri, A.; Otega-Prieto, A.; Van de Klundert, M.; Wettengel, J.; Durantel, D.; Dorner, M.; Klenerman, P.; Protzer, U.; Giotis, S.; McKeating, J. A.
10.1101/2020.03.27.011841 — microbiology — Posted on 2020-03-29
376 APOBEC3C tandem domain proteins create super restriction factors against HIV-1
McDonnell, M. M.; Crawford, K. H.; Dingens, A. S.; Bloom, J. D.; Emerman, M.
10.1101/2020.03.27.012963 — microbiology — Posted on 2020-03-29
382 Genomic evidence for recurrent genetic admixture during domestication mediterranean olive trees (Olea europaea).
Julca, I.; Marcet-Houben, M.; Cruz, F.; Gomez-Garrido, J.; Gaut, B. S.; Diez, C. M.; Gut, I. G.; Alioto, T. S.; Vargas, P.; Gabaldon, T.
10.1101/2020.03.28.013227 — evolutionary biology — Posted on 2020-03-29
383 Drivers of change and ecosystem status in a temperate lake over the last Post-Glacial period from 14.5 kyr
Tonno, I.; Freiberg, R.; Talas, L.; Kisand, A.; Belle, S.; Stivrins, N.; Alliksaar, T.; Heinsalu, A.; Veski, S.; Kisand, V.
10.1101/2020.03.27.011502 — ecology — Posted on 2020-03-29
388 Pyocin efficacy in a murine model of Pseudomonas aeruginosa sepsis
Six, A.; Mosbahi, K.; Barge, M.; Kleanthous, C.; Evans, T.; Walker, D.
10.1101/2020.03.27.011908 — microbiology — Posted on 2020-03-29
389 Secreted TAL effectors protect symbiotic bacteria from entrapment within fungal hyphae
Richter, I.; Uzum, Z.; Stanley, C. E.; Moebius, N.; Stinear, T. P.; Pidot, S. S.; Ferling, I.; Hillmann, F.; Hertweck, C.
10.1101/2020.03.28.013177 — microbiology — Posted on 2020-03-29
394 Loss of Activating Transcription Factor 3 prevents KRAS-mediated pancreatic cancer
Azizi, N.; Toma, J.; Martin, M.; Khalid, M. F.; Steele, N.; Shi, J.; Pasca Di Magliano, M.; Pin, C. L.
10.1101/2020.03.27.011601 — cancer biology — Posted on 2020-03-29
396 A Reference Feature based method for Quantification and Identification of LC-MS based untargeted metabolomics
luan, e.; cheng, k.; long, q.; li, d.; li, z.; liu, b.; wang, y.; li, w.; guo, b.; tan, f.; yi, x.; feng, l.; song, j.; zheng, h.
10.1101/2020.03.26.010769 — bioinformatics — Posted on 2020-03-29
399 Cell-cell adhesion in plant grafting is facilitated by β-1,4-glucanases
Notaguchi, M.; Kurotani, K.-i.; Sato, Y.; Tabata, R.; Kawakatsu, Y.; Okayasu, K.; Sawai, Y.; Okada, R.; Asahina, M.; Ichihashi, Y.; Shirasu, K.; Suzuki, T.; Niwa, M.; Higashiyama, T.
10.1101/2020.03.26.010744 — plant biology — Posted on 2020-03-29
401 Disarrangement of Endoplasmic reticulum-mitochondria communication impairs Ca2+ homeostasis in FRDA
Rodriguez, L. R.; Calap-Quintana, P.; Lapena-Luzon, T.; Pallardo, F. V.; Schneuwly, S.; Navarro Langa, J. A.; Gonzalez-Cabo, P.
10.1101/2020.03.27.011528 — neuroscience — Posted on 2020-03-29
402 Zika virus replicates in skeletal muscle contributing to peripheral viral amplification prior to reach neural tissue
Gavino-Leopoldino, D.; Figueiredo, C. M.; Barcellos, L. G.; Silva, M. O. L. d.; Araujo, S. M. B.; Neris, R. L. d. S.; Miranda, L. D.; Ladislau, L.; Benjamin, C. F.; Da Poian, A. T.; Clark, J. R.; Figueiredo, C. P.; Assuncao-Miranda, I.
10.1101/2020.03.26.010389 — microbiology — Posted on 2020-03-29
406 A Comprehensive Multi-Center Cross-platform Benchmarking Study of Single-cell RNA Sequencing Using Reference Samples
FDA SEQC-2 Single-cell Sequencing Consortium, ; Chen, W.; Zhao, Y.; Chen, X.; Xu, X.; Yang, Z.; Bi, Y.; Chen, V.; Li, J.; Choi, H.; Ernest, B.; Tran, B.; Mehta, M.; Moos, M.; Farmer, A.; Mir, A.; Kumar, P.; Mehra, U.; Li, J.-L.; Xiao, W.; Wang, C.
10.1101/2020.03.27.010249 — genomics — Posted on 2020-03-29
408 Evolutionarily conserved non-protein-coding regions in the chicken genome harbor functionally important variation
Gross, C.; Bortoluzzi, C.; de Ridder, D.; Megens, H.-J.; Groenen, M.; Reinders, M.; Bosse, M.
10.1101/2020.03.27.012005 — genomics — Posted on 2020-03-29
410 The Forensic Landscape and the Population Genetic Analyses of Hainan Li Based on Massively Parallel Sequencing DNA Profiling
Fan, H.; Du, Z.; Wang, F.; Wang, X.; Wen, S.-Q.; Wang, L.; Du, P.; Liu, H.; Cao, S.; Luo, Z.; Han, B.; Huang, P.; Zhu, B.; Qiu, P.
10.1101/2020.03.27.011064 — genetics — Posted on 2020-03-29
413 Frisky CALF outruns LASSO
Jeffries, C. D.; Ford, J. R.; Tilson, J. L.; Perkins, D. O.; Bost, D.; Filer, D.; Wilhelmsen, K. C.
10.1101/2020.03.27.011700 — bioinformatics — Posted on 2020-03-29
417 Recent loss of the Dim2 cytosine DNA methyltransferase impacts mutation rate and evolution in a fungal plant pathogen
Moeller, M.; Habig, M.; Lorrain, C.; Feurtey, A.; Haueisen, J.; Fagundes, W. C.; Alizadeh, A.; Freitag, M.; Stukenbrock, E. H.
10.1101/2020.03.27.012203 — genetics — Posted on 2020-03-29
418 Individualized System for Augmenting Ventilator Efficacy (iSAVE):A Rapidly deployable system to expand ventilator capacity
Srinivasan, S.; Ramadi, K.; Vicario, F.; Gwynne, D.; Hayward, A.; Langer, R.; Frassica, J.; Baron, R.; Traverso, G.
10.1101/2020.03.28.012617 — physiology — Posted on 2020-03-29
420 A novel germline mutation in the POT1 gene predisposes to familial non-medullary thyroid cancer
Srivastava, A.; Miao, B.; Skopelitou, D.; Kumar, V.; Kumar, A.; Paramasivam, N.; Bonora, E.; Hemminki, K.; Försti, A.; Bandapalli, O. R.
10.1101/2020.03.23.004663 — genomics — Posted on 2020-03-29
425 Disease-specific variant pathogenicity prediction significantly improves variant interpretation in inherited cardiac conditions
Zhang, X.; Walsh, R.; Whiffin, N.; Buchan, R.; Midwinter, W.; Wilk, A.; Govind, R.; Li, N.; Ahmad, M.; Mazzarotto, F.; Roberts, A.; Theotokis, P.; Mazaika, E.; Allouba, M.; de Marvao, A.; Pua, C. J.; Day, S. M.; Ashley, E.; Colan, S. D.; Michels, M.; Pereira, A. C.; Jacoby, D.; Ho, C. Y.; Olivotto, I.; Gunnarsson, G. T.; Jefferies, J.; Semsarian, C.; Ingles, J.; O'Regan, D. P.; Aguib, Y.; Yacoub, M. H.; Cook, S.; Barton, P. J. R.; Bottolo, L.; Ware, J. S.
10.1101/2020.03.27.010736 — genetics — Posted on 2020-03-29
426 Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins
Saha, P.; Shumate, J. L.; Caldwell, J. G.; Elghobashi-Meinhardt, N.; Lu, A.; Zhang, L.; Olsson, N.; Elias, J. E.; Pfeffer, S. R.
10.1101/2020.03.26.009217 — biochemistry — Posted on 2020-03-29
428 Detection of deleterious on-target effects after HDR-mediated CRISPR editing
Weisheit, I.; Kroeger, J. A.; Malik, R.; Klimmt, J.; Crusius, D.; Dannert, A.; Dichgans, M.; Paquet, D.
10.1101/2020.03.27.012104 — genomics — Posted on 2020-03-29
431 tructural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL
Sloan, J.; Hankenjos, J.; Gebert, M.; Ermakova, O.; Gumiero, A.; Stier, G.; Wild, K.; Sinning, I.; Lohmann, J. U.
10.1101/2020.03.26.009761 — plant biology — Posted on 2020-03-29
432 Anticipatory responses along motion trajectories in awake monkey area V1
Benvenuti, G.; Chemla, S.; Boonman, A.; Perrinet, L.; Masson, G. S.; Chavane, F.
10.1101/2020.03.26.010017 — neuroscience — Posted on 2020-03-29
434 Non-invasive surveys of mammalian viruses using environmental DNA
Alfano, N.; Dayaram, A.; Axtner, J.; Tsangaras, K.; Kampmann, M.-L.; Mohamed, A.; Wong, S. T.; Gilbert, M. T. P.; Wilting, A.; Greenwood, A. D.
10.1101/2020.03.26.009993 — molecular biology — Posted on 2020-03-29
436 Dissecting the toxicity and mitigating the impact of harmful Prymnesium blooms in the UK waters of the Norfolk Broads
Wagstaff, B. A.; Pratscher, J.; Rivera, P. P. L.; Hems, E. S.; Brooks, E.; Rejzek, M.; Todd, J. D.; Murrell, J. C.; Field, R. A.
10.1101/2020.03.26.010066 — microbiology — Posted on 2020-03-29
440 CRISPR/Cas9 mediated mutations as a new tool for studying taste in honeybees
Degirmenci, L.; Geiger, D.; Roge Ferreira, F.; Keller, A.; Krischke, B.; Beye, M.; Steffan-Dewenter, I.; Scheiner, R.
10.1101/2020.03.26.009696 — genetics — Posted on 2020-03-29
442 Engineered chemotaxis core signaling units indicate a constrained kinase-off state
Muok, A.; Khiang Chua, T.; Srivastava, M.; Yang, W.; Maschmann, Z.; Borbat, P. P.; Chong, J.; Zhang, S.; Freed, J. H.; Briegel, A.; Crane, B. R.
10.1101/2020.03.27.011866 — biochemistry — Posted on 2020-03-29
445 Evaluating the transcriptional fidelity of cancer models
Peng, D.; Gleyzer, R.; Tai, W.-H.; Kumar, P.; Bian, Q.; Issacs, B.; Lummertz da Rocha, E.; Cai, S.; DiNapoli, K.; Cahan, P.
10.1101/2020.03.27.012757 — bioinformatics — Posted on 2020-03-29
448 Developmental atlas of white lupin cluster roots
Gallardo, C.; Hufnagel, B.; Soriano, A.; Divol, F.; Marques, L.; Doumas, P.; Peret, B.
10.1101/2020.03.26.009910 — plant biology — Posted on 2020-03-29
451 An optogenetic switch for the Set2 methyltransferase provides evidence for rapid transcription-dependent and independent dynamics of H3K36 methylation
Lerner, A. M.; Hepperla, A. J.; Meriesh, H.; Keele, G. R.; Yumerefendi, H.; Restrepo, D.; Zimmerman, S.; Bear, J.; Kuhlman, B.; Davis, I. J.; Strahl, B. D.
10.1101/2020.03.28.013706 — molecular biology — Posted on 2020-03-29
452 Sterol-response pathways mediate alkaline survival in diverse fungi
Brown, H. E.; Telzrow, C. L.; Saelens, J. W.; Fernandes, L.; Alspaugh, J. A.
10.1101/2020.03.26.010983 — microbiology — Posted on 2020-03-29
453 Mechano-bactericidal nanopillars require external forces to effectively kill bacteria
Valiei, A.; Lin, N.; Bryche, J.-F.; McKay, G.; Canva, M.; Charette, P.; Nguyen, D.; Moraes, C.; Tufenkji, N.
10.1101/2020.03.27.012153 — microbiology — Posted on 2020-03-29
454 Molecular and functional diversity of distinct subpopulations of extracellular vesicles from stressed pancreatic beta cells: implications for autoimmunity
Giri, K. R.; De Beaurepaire, L.; Jegou, D.; Lavy, M.; Mosser, M.; Dupont, A.; Fleurisson, R.; Dubreil, L.; Collot, M.; Van Endert, P.; Bach, J.-M.; Mignot, G.; Bosch, S.
10.1101/2020.03.26.003145 — immunology — Posted on 2020-03-29
455 A novel rare c. -39C>T mutation in the PROS1 5'UTR causing PS deficiency by creating a new upstream translation initiation codon and inhibiting the production of the natural protein.
Labrouche-Colomer, S.; Soukarieh, O.; Proust, C.; Mouton, C.; Huguenin, Y.; Roux, M.; Besse, C.; Boland, A.; Olaso, R.; Constans, J.; Deleuze, J.-F.; Morange, P.-E.; Jaspard-Vinassa, B.; Tregouet, D.-A.
10.1101/2020.03.28.007328 — genetics — Posted on 2020-03-29
460 Competitive learning suggests circulating miRNA profiles for cancers decades prior to diagnosis
Keller, A.; Fehlmann, T.; Backes, C.; Kern, F.; Gislefoss, R.; Langseth, H.; Rounge, T. B.; Ludwig, N.; Meese, E.
10.1101/2020.03.26.009597 — cancer biology — Posted on 2020-03-29
462 Ultrasensitive small molecule fluorogenic probe for human heparanase
Liu, J.; Schleyer, K. A.; Bryan, T. L.; Xie, C.; Seabra, G.; Xu, Y.; Kafle, A.; Cui, C.; Wang, Y.; Yin, K.; Fetrow, B.; Henderson, P. K. P.; Fatland, P. Z.; Liu, J.; Li, C.; Guo, H.; Cui, L.
10.1101/2020.03.26.008730 — biochemistry — Posted on 2020-03-29
468 Genetic profiling of Vietnamese population from large-scale genomic analysis of non-invasive prenatal testing data
Tran, N. H.; Vo, T. B.; Nguyen, V. T.; Tran, N. T.; Trinh, T.-H. N.; Pham, H.-A. T.; Dao, H. T.; Nguyen, N. M.; Van, Y.-L. T.; Tran, V. U.; Vu, H. G.; Bui, Q.-T. N.; Vo, P.-A. N.; Nguyen, H. N.; Nguyen, Q.-T. T.; Do, T.-T. T.; Cao Thi Ngoc, P.; Truong, D. K.; Nguyen, H.-N.; Giang, H.; Phan, M.-D.
10.1101/868588 — genomics — Posted on 2020-03-29
470 CyclinD1 controls development of cerebellar granule cell progenitors through phosphorylation and stabilization of ATOH1
Miyashita, S.; Owa, T.; Seto, Y.; Yamashita, M.; Aida, S.; Nishioka, T.; Kaibuchi, K.; Kawaguchi, Y.; Taya, S.; Hoshino, M.
10.1101/2020.03.27.010926 — developmental biology — Posted on 2020-03-29
471 Structure of Mpro from COVID-19 virus and discovery of its inhibitors
Jin, Z.; Du, X.; Xu, Y.; Deng, Y.; Liu, M.; Zhao, Y.; Zhang, B.; Li, X.; Zhang, L.; Peng, C.; Duan, Y.; Yu, J.; Wang, L.; Yang, K.; Liu, F.; Jiang, R.; Yang, X.; You, T.; Liu, X.; Yang, X.; Bai, F.; Liu, H.; Liu, X.; Guddat, L. W.; Xu, W.; Xiao, G.; Qin, C.; Shi, Z.; Jiang, H.; Rao, Z.; Yang, H.
10.1101/2020.02.26.964882 — biochemistry — Posted on 2020-03-29
472 Molecular determinants of β-arrestin coupling to formoterol-bound β1-adrenoceptor
Lee, Y.; Warne, T.; Nehme, R.; Pandey, S.; Chaturvedi, M.; Dwivedi-Agnihotri, H.; Edwards, P.; Garcia-Nafria, J.; Leslie, A.; SHUKLA, A. K.; Tate, C. G.
10.1101/2020.03.27.011585 — molecular biology — Posted on 2020-03-29
473 Codon usage and evolutionary rates of the 2019-nCoV genes
Dilucca, M.; Pavlopoulou, A.; Forcelloni, S.; GIANSANTI, A.; Georgakilas, A. G.
10.1101/2020.03.25.006569 — genomics — Posted on 2020-03-29
477 Differential diffusional properties in loose and tight docking prior to membrane fusion
Witkowska, A.; Spindler, S.; Gholami Mahmoodabadi, R.; Sandoghdar, V.; Jahn, R.
10.1101/2020.03.28.013482 — biophysics — Posted on 2020-03-29
478 Transiently structured head domains control intermediate filament assembly
zhou, x.; Lin, Y.; Liszczak, G.; Sysoev, V.; Sutherland, L.; Mori, E.; Murray, D.; Kato, M.; Tycko, R.; McKnight, S. L.
10.1101/2020.03.27.012112 — biochemistry — Posted on 2020-03-29
481 TDP-43 and HSP70 phase separate into anisotropic, intranuclear liquid spherical annuli
Yu, H.; Lu, S.; Gasior, K.; Singh, D.; Tapia, O.; Vazquez-Sanchez, S.; Toprani, D.; Beccari, M.; Yates, J. R.; Da Cruz, S.; Newby, J.; Larfaga, M.; Gladfelter, A.; Villa, E.; Cleveland, D. W.
10.1101/2020.03.28.985986 — cell biology — Posted on 2020-03-29
482 A global Ramachandran score identifies protein structures with unlikely stereochemistry
Sobolev, O. V.; Afonine, P. V.; Moriarty, N. W.; Hekkelman, M. L.; Joosten, R. P.; Perrakis, A.; Adams, P. D.
10.1101/2020.03.26.010587 — biophysics — Posted on 2020-03-29
483 Left-handed DNA-PAINT for improved superresolution imaging in the nucleus.
Geertsema, H.; Aimola, G.; Fabricius, V.; Fuerste, J. P.; Kaufer, B.; Ewers, H.
10.1101/2020.03.28.010553 — biophysics — Posted on 2020-03-29
487 Molecular architecture of the luminal ring of the Xenopus laevis nuclear pore complex
Zhang, Y.; Li, S.; Zeng, C.; Huang, G.; Zhu, X.; Wang, Q.; Wang, K.; Zhou, Q.; Zhang, W.; Yang, G.; Liu, M.; Tao, Q.; Lei, J.; Shi, Y.
10.1101/2020.03.27.009381 — biophysics — Posted on 2020-03-29
488 Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail
Zhang, Y.; Inoue, M.; Tsutsumi, A.; Watanabe, S.; Nishizawa, T.; Nagata, K.; Kikkawa, M.; Inaba, K.
10.1101/2020.03.28.012849 — biochemistry — Posted on 2020-03-29
490 Identification and characterization of diverse OTU deubiquitinases in bacteria
Schubert, A. F.; Nguyen, J. V.; Franklin, T. G.; Geurink, P. P.; Roberts, C. G.; Sanderson, D. J.; Miller, L. N.; Ovaa, H.; Hofmann, K.; Pruneda, J. N.; Komander, D.
10.1101/2020.03.28.013474 — biochemistry — Posted on 2020-03-29
491 Identification of a Novel PP2A Regulator, WNK1, as Critical For Uterine Function
Chi, R.-p. A.; Wang, T.; Huang, C.-l.; Wu, S.-P.; Young, S. L.; Lydon, J. P.; DeMayo, F. J.
10.1101/2020.03.27.012039 — developmental biology — Posted on 2020-03-29
492 Induced Pluripotent Stem Cell-derived CAR-Macrophage Cells with Antigen-dependent Anti-Cancer Cell Functions for Liquid and Solid Tumors
Zhang, L.; Tian, L.; Dai, X.; Yu, H.; Wang, J.; Lei, A.; Zhao, W.; Zhu, Y.; Sun, Z.; Zhang, H.; Church, G.; Huang, H.; Weng, Q.; Zhang, J.
10.1101/2020.03.28.011270 — cell biology — Posted on 2020-03-29
493 Partnership between epigenetic reader BRD4 and transcription factor CEBPD
Wang, Q.; Zhang, M.; Urabe, G.; Wang, B.; Ozer, G.; Huang, Y.; Kent, K. C.; Guo, L.
10.1101/2020.03.27.012674 — cell biology — Posted on 2020-03-29
494 Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer
Cross, W.; Mossner, M.; Nowinski, S.; Cresswell, G.; Banerjee, A.; Williams, M.; Gay, L.; Baker, A.-M.; Kimberley, C.; Davis, H.; Martinez, P.; Traki, M.; Walther, V.; Smith, K.; Caravagna, G.; Amarasingam, S.; Elia, G.; Berner, A. M.; Choi, R. C.; Ramagiri, P.; Chauhan, R.; Matthews, N.; Murphy, J.; Antoniou, A.; Clark, S.; Aleong, J.-A. C.; Domingo, E.; Spiteri, I. S.; McDonald, S.; Shibata, D.; Lacle, M. M.; Wang, L. M.; Moorghen, M.; Tomlinson, I.; Novelli, M.; Jansen, M.; Watson, A.; Wright, N. A.; Bridgewater, J.; Rodriguez-Justo, M.; Kocher, H.; Leedham, S.; Sottoriva, A.; Graham, T. A.
10.1101/2020.03.26.007138 — cancer biology — Posted on 2020-03-29
495 Extended depth of focus multiphoton microscopy via incoherent pulse splitting
Chen, B.; Chakraborty, T.; Daetwyler, S.; Manton, J.; Dean, K.; Fiolka, R.
10.1101/2020.03.27.012260 — biophysics — Posted on 2020-03-29
498 Evolution of an interaction between disordered proteins resulted in increased heterogeneity of the binding transition state
Karlsson, E.; Paissoni, C.; Erkelens, A.; Tehranizadeh, Z. A.; Sorgenfrei, F. A.; Andersson, E.; Ye, W.; Camilloni, C.; Jemth, P.
10.1101/2020.03.27.012328 — biophysics — Posted on 2020-03-29
499 New and improved GRAB fluorescent sensors for monitoring dopaminergic activity in vivo
Sun, F.; Zhou, J.; Dai, B.; Qian, T.; Zeng, J.; Li, X.; Zhuo, Y.; Zhang, Y.; Tan, K.; Feng, J.; Dong, H.; Qian, C.; Lin, D.; Cui, G.; Li, Y.
10.1101/2020.03.28.013722 — neuroscience — Posted on 2020-03-28
500 Sexually Antagonistic Selection on Genetic Variation is Rare in Humans
Kasimatis, K. R.; Abraham, A.; Ralph, P. L.; Kern, A. D.; Capra, J. A.; Phillips, P. C.
10.1101/2020.03.26.009670 — evolutionary biology — Posted on 2020-03-28
504 Microscopic and mesoscopic effects of reward uncertainty in monkey fronto-parietal areas
Taghizadeh, B.; Foley, N. C.; Karimimehr, S.; Cohanpour, M.; Semework, M.; Sheth, S. A.; Lashgari, R.; Gottlieb, J.
10.1101/2019.12.17.879262 — neuroscience — Posted on 2020-03-28
505 Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1.
Szymanska, K.; Boldt, K.; Logan, C. V.; Adams, M.; Robinson, P. A.; Ueffing, M.; Zeqiraj, E.; Wheway, G.; Johnson, C. A.
10.1101/2020.01.08.897959 — molecular biology — Posted on 2020-03-28
508 DOCK3 is a dosage-sensitive regulator of skeletal muscle and Duchenne muscular dystrophy-associated pathologies.
Reid, A. L.; Wang, Y.; Samani, A.; Hightower, R. M.; Lopez, M. A.; Gilbert, S. R.; Ianov, L.; Crossman, D. K.; Dell Italia, L. J.; Millay, D. P.; van Groen, T.; Halade, G. V.; Alexander, M. S.
10.1101/2020.03.27.010223 — genetics — Posted on 2020-03-28
511 Pyk2 Overexpression in Postsynaptic Neurons Blocks Aβ1-42-induced Synaptotoxicity in a Microfluidic Co-Culture Model
Kilinc, D.; Vreulx, A.-C.; Mendes, T.; Flaig, A.; Marques-Coelho, D.; Verschoore, M.; Demiautte, F.; Amouyel, P.; Neuro-CEB Brain Bank, ; Eysert, F.; Dourlen, P.; Chapuis, J.; Costa, M. R.; Malmanche, N.; Checler, F.; Lambert, J.-C.
10.1101/2019.12.20.884205 — neuroscience — Posted on 2020-03-28
514 Characterizing and inferring quantitative cell cycle phase in single-cell RNA-seq data analysis
Hsiao, C. J.; Tung, P.; Blischak, J. D.; Burnett, J.; Barr, K. A.; Dey, K. K.; Stephens, M.; Gilad, Y.
10.1101/526848 — genomics — Posted on 2020-03-28
515 Insights on the taxonomy and ecogenomics of the Synechococcus collective
Salazar, V. W.; Thompson, C. C.; Tschoeke, D. A.; Swings, J.; Mattoso, M.; Thompson, F. L.
10.1101/2020.03.20.999532 — microbiology — Posted on 2020-03-28
518 The Nucleocapsid Protein of SARS-CoV-2 Abolished Pluripotency in Human Induced Pluripotent Stem Cells
Lin, Z.; Gao, Q.; Fang, Q.; Mai, J.; Zhou, L.; Lin, X.; Qian, Y.; Cai, T.; Chen, Z.; Wang, P.; Lin, B.
10.1101/2020.03.26.010694 — cell biology — Posted on 2020-03-28
519 Structure-Based Design, Synthesis and Biological Evaluation of Peptidomimetic Aldehydes as a Novel Series of Antiviral Drug Candidates Targeting the SARS-CoV-2 Main Protease
Dai, W.; Zhang, B.; Jiang, X.-M.; Su, H.; Li, J.; Zhao, Y.; Xie, X.; Jin, Z.; Peng, J.; Liu, F.; Li, C.; Li, Y.; Bai, F.; Wang, H.; Cheng, X.; Cen, X.; Hu, S.; Yang, X.; Wang, J.; Liu, X.; Xiao, G.; Jiang, H.; Rao, Z.; Zhang, L.; Xu, Y.; Yang, H.; Liu, H.
10.1101/2020.03.25.996348 — biochemistry — Posted on 2020-03-28
520 SARS-CoV-2 proteome microarray for mapping COVID-19 antibody interactions at amino acid resolution
Wang, H.; Hou, X.; Wu, X.; Liang, T.; Zhang, X.; Wang, D.; Teng, F.; Dai, J.; Duan, H.; Guo, S.; Li, Y.; Yu, X.
10.1101/2020.03.26.994756 — biochemistry — Posted on 2020-03-28
521 Structural Basis for Potent Neutralization of Betacoronaviruses by Single-domain Camelid Antibodies
Wrapp, D.; De Vlieger, D.; Corbett, K. S.; Torres, G. M.; Van Breedam, W.; Roose, K.; van Schie, L.; VIB-CMB COVID-19 Response Team, ; Hoffmann, M.; Pöhlmann, S.; Graham, B. S.; Callewaert, N.; Schepens, B.; Saelens, X.; McLellan, J. S.
10.1101/2020.03.26.010165 — microbiology — Posted on 2020-03-28
522 Site-specific analysis of the SARS-CoV-2 glycan shield
Watanabe, Y.; Allen, J. D.; Wrapp, D.; McLellan, J. S.; Crispin, M.
10.1101/2020.03.26.010322 — microbiology — Posted on 2020-03-28
523 SARS-CoV-2 and ORF3a: Non-Synonymous Mutations and Polyproline Regions
Issa, E.; Merhi, G.; Panossian, B.; Salloum, T.; Tokajian, S. T.
10.1101/2020.03.27.012013 — genomics — Posted on 2020-03-28
524 SARS-CoV-2 exhibits intra-host genomic plasticity and low-frequency polymorphic quasispecies
Karamitros, T.; Papadopoulou, G.; Bousali, M.; Mexias, A.; Tsiodras, S.; Mentis, A.
10.1101/2020.03.27.009480 — genomics — Posted on 2020-03-28
531 Inhibition of the SUV4-20 H1 histone methyltransferase increases frataxin expression in Friedreich's ataxia patient cells
Vilema-Enriquez, G.; Quinlan, R.; Kilfeather, P.; Mazzone, R.; Saqlain, S.; del Molino del Barrio, I.; Donato, A.; Corda, G.; Li, F.; Vedadi, M.; Nemeth, A. H.; Brennan, P. E.; Wade-Martins, R.
10.1101/2020.03.26.010439 — neuroscience — Posted on 2020-03-28
532 A second hybrid-binding domain modulates the activity of Drosophila ribonuclease H1
Gonzalez de Cozar, J. M.; Carretero-Junquera, M.; Ciesielski, G. L.; Miettinen, S.; Varjosalo, M.; Kaguni, L. S.; Dufour, E.; Jacobs, H. T.
10.1101/2020.03.26.010645 — molecular biology — Posted on 2020-03-28
533 Pancreatlas: a comprehensive and interactive image atlas of the human pancreas in health and disease
Saunders, D. C.; Messmer, J.; Kusmartseva, I.; Beery, M. L.; Yang, M.; Atkinson, M. A.; Powers, A. C.; Cartailler, J.-P.; Brissova, M.
10.1101/2020.03.27.006320 — cell biology — Posted on 2020-03-28
534 Redirected tropisms of extracellular vesicles and exomeres yield distinct biodistribution profiles
Wu, A. Y.-T.; Sung, Y.-C.; Chou, S. T.-Y.; Guo, V.; Chien, J. C.-Y.; Ko, J. J.-S.; Yang, A. L.; Chuang, J.-C.; Huang, H.-C.; Wu, Y.; Ho, M.-R.; Ericsson, M.; Lin, W.-W.; Cheung, C. H. Y.; Juan, H.-F.; Ueda, K.; Chen, Y.; Lai, C. P.-K.
10.1101/2020.03.27.012625 — cell biology — Posted on 2020-03-28
535 Primate naive pluripotent stem cells stall in the G1 phase of the cell cycle and differentiate prematurely during embryo colonization
Aksoy, I.; Rognard, C.; Moulin, A.; Marcy, G.; Masfaraud, E.; Wianny, F.; Cortay, V.; Bellemin-Menard, A.; Doerflinger, N.; Dirheimer, M.; Mayere, C.; Lynch, C.; Raineteau, O.; Joly, T.; Dehay, C.; Serrano, M.; Afanassieff, M.; Savatier, P.
10.1101/2020.03.27.011890 — cell biology — Posted on 2020-03-28
536 O-GlcNAc regulates gene expression by controlling detained intron splicing
Tan, Z.-W.; Fei, G. Q.; Paulo, J.; Bellaousov, S.; Martin, S. E. S.; Duveau, D.; Thomas, C.; Gygi, S.; Boutz, P.; Walker, S.
10.1101/2020.03.27.012781 — cell biology — Posted on 2020-03-28
537 Large-scale Phenotypic Drug Screen Identifies Neuroprotectants in Zebrafish and Mouse Models of Retinitis Pigmentosa
Zhang, L.; Chen, C.; Fu, J.; Lilley, B.; Berlinicke, C.; Hansen, B.; Ding, D.; Wang, G.; Wang, T.; Daniel, D.; Ye, Y.; Saxena, M. T.; Hall, K. R.; Sharrock, A. V.; Brandon, C.; Shim, J. S.; Hanes, J.; Ji, H.; Liu, J. O.; Qian, J.; Ackerley, D. F.; Rohrer, B.; Zack, D.; Mumm, J. S.
10.1101/2020.03.26.010009 — neuroscience — Posted on 2020-03-28
538 The transcription factor TRF2 has a unique function in regulating cell cycle and apoptosis
Kedmi, A.; Sloutskin, A.; Epstein, N.; Gasri-Plotnitsky, L.; Ickowicz, D.; Shoval, I.; Doniger, T.; Darmon, E.; Ideses, D.; Porat, Z.; Yaron, O.; Juven-Gershon, T.
10.1101/2020.03.27.011288 — molecular biology — Posted on 2020-03-28
539 Maternal DNMT3A-dependent de novo methylation of the zygotic paternal genome inhibits gene expression in the early embryo
Richard Albert, J.; Au Yeung, W. K.; Toriyama, K.; Kobayashi, H.; Hirasawa, R.; Brind'Amour, J.; Bogutz, A. B.; Sasaki, H.; Lorincz, M. C.
10.1101/2020.03.26.009977 — developmental biology — Posted on 2020-03-28
540 Structure of the Cytoplasmic Ring of the Xenopus laevis Nuclear Pore Complex
Huang, G.; Zhang, Y.; Zhu, X.; Zeng, C.; Wang, Q.; Zhou, Q.; Tao, Q.; Liu, M.; Lei, J.; Yan, C.; Shi, Y.
10.1101/2020.03.27.009407 — biophysics — Posted on 2020-03-28
549 Morphological peculiarities of DNA-protein complexes in dormant Escherichia coli cells, subjected to prolonged starvation
Krupyanskii, Y.; Loiko, N.; Danilova, Y.; Moiseenko, A.; Kovalenko, V.; Tereshkina, K.; El-REgistan, G.; Sokolova, O.
10.1101/2020.03.27.011494 — cell biology — Posted on 2020-03-27
551 EphA7 Isoforms Differentially Regulate Cortical Dendrite Development
Leonard, C. E.; Baydyuk, M.; Stepler, M. A.; Burton, D. A.; Donoghue, M. J.
10.1101/2020.03.27.011486 — neuroscience — Posted on 2020-03-27
553 Distinct Neuronal Populations Contribute to Trace Conditioning and Extinction Learning in the Hippocampal CA1
Mount, R.; Hansen, K. R.; Sridhar, S.; Mohammed, A. I.; Abdulkerim, M. E.; Kessel, R.; Nazer, B.; Gritton, H. J.; Han, X.
10.1101/2020.03.06.980854 — neuroscience — Posted on 2020-03-27
554 Geological degassing enhances microbial metabolism in the continental subsurface
Bornemann, T. L.; Adam, P. S.; Turzynski, V.; Schreiber, U.; Figueroa-Gonzalez, P. A.; Rahlff, J.; Koester, D.; Schmidt, T. C.; Schunk, R.; Krauthausen, B.; Probst, A. J.
10.1101/2020.03.07.980714 — microbiology — Posted on 2020-03-27
556 Megafauna decline have reduced pathogen dispersal which may have increased emergent infectious diseases
Doughty, C.; Prys-Jones, T.; Faurby, S.; Abraham, A.; Hepp, C.; Fofanov, V.; Leshyk, V.; Svenning, J.-C.; Galetti, M.
10.1101/2020.01.21.914531 — ecology — Posted on 2020-03-27
558 Defining totipotency using criteria of increasing stringency
Posfai, E.; Schell, J. P.; Janiszewski, A.; Rovic, I.; Murray, A.; Bradshaw, B.; Pardon, T.; El Bakkali, M.; Talon, I.; De Geest, N.; Kumar, P.; To, S. K.; Petropoulos, S.; Jurisicova, A.; Pasque, V.; Lanner, F.; Rossant, J.
10.1101/2020.03.02.972893 — cell biology — Posted on 2020-03-27
560 Binding of the motor protein SecA to the bacterial protein translocation channel SecYEG in the absence of ATP
Winkler, K.; Karner, A.; Horner, A.; Hannesschlaeger, C.; Knyazev, D.; Siligan, C.; Zimmermann, M.; Kuttner, R.; Pohl, P.; Preiner, J.
10.1101/799247 — biophysics — Posted on 2020-03-27
561 SCOUT: Single-cell outlier analysis in cancer
Onzi, G. R.; Faccioni, J. L.; Alvarado, A. G.; Bracco, P. A.; Kornblum, H. L.; Lenz, G.
10.1101/2020.03.25.007518 — bioinformatics — Posted on 2020-03-27
562 The Hrq1 helicase stimulates Pso2 translesion nuclease activity to promote DNA inter-strand crosslink repair
Rogers, C. M.; Lee, C.-Y.; Parkins, S.; Buehler, N. J.; Wenzel, S.; Martinez-Marquez, F.; Takagi, Y.; Myong, S.; Bochman, M. L.
10.1101/773267 — biochemistry — Posted on 2020-03-27
563 Mathematical modeling of plant cell fate transitions controlled by hormonal signals
Klawe, F. Z.; Stiehl, T.; Bastian, P.; Gaillochet, C.; Lohmann, J. U.; Marciniak-Czochra, A.
10.1101/830190 — systems biology — Posted on 2020-03-27
565 Establishment of Proximity-dependent Biotinylation Approaches in Different Plant Model Systems
Arora, D.; B. Abel, N.; Liu, C.; Van Damme, P.; Yperman, K.; Dai Vu, L.; Wang, J.; Tornkvist, A.; Impens, F.; Korbei, B.; Eeckhout, D.; Van Leene, J.; Goossens, A.; De Jaeger, G.; Ott, T.; Moschou, P.; Van Damme, D.
10.1101/701425 — plant biology — Posted on 2020-03-27
566 Genome sequences of both organelles of the grapevine rootstock cultivar 'Börner'
Frommer, B.; Holtgräwe, D.; Hausmann, L.; Viehöver, P.; Huettel, B.; Töpfer, R.; Weisshaar, B.
10.1101/2020.03.18.996405 — plant biology — Posted on 2020-03-27
567 Pulmonary acini exhibit complex changes during postnatal rat lung development
Haberthür, D.; Yao, E.; Barre, S. F.; Cremona, T. P.; Tschanz, S. A.; Schittny, J. C.
10.1101/786681 — physiology — Posted on 2020-03-27
569 The circadian dynamics of the hippocampal transcriptome and proteome is altered in experimental epilepsy
Debski, K.; Ceglia, N.; Ghestem, A.; Ivanov, A.; Brancati, G. E.; Broer, S.; Bot, A.; Muller, A.; Schoch, S.; Becker, A.; Loscher, W.; Guye, M.; Sassone-Corsi, P.; Lukasiuk, K.; Baldi, P.; Bernard, C.
10.1101/199372 — neuroscience — Posted on 2020-03-27
570 SynaptoPAC, an Optogenetic Tool for Induction of Presynaptic Plasticity
Oldani, S.; Moreno-Velasquez, L.; Stumpf, A.; Rosenmund, C.; Schmitz, D.; Rost, B. R.
10.1101/2020.03.27.011635 — neuroscience — Posted on 2020-03-27
572 Insulin-Like Growth Factor I Modulates Sleep Through Hypothalamic Orexin Neurons
Zegarra-Valdivia, J. A.; Pignatelli, J.; Fernandez de Sevilla, E.; Fernandez, A. M.; Munive, V. A.; Martinez-Rachadell, L.; Nunez, A.; Torres Aleman, I.
10.1101/2020.03.20.000000 — neuroscience — Posted on 2020-03-27
575 Direct visualization and characterization of the human zona incerta and surrounding structures
Lau, J. C.; Xiao, Y.; Haast, R. A.; Gilmore, G.; Uludag, K.; MacDougall, K. W.; Menon, R. R.; Parrent, A. G.; Peters, T. M.; Khan, A. R.
10.1101/2020.03.25.008318 — neuroscience — Posted on 2020-03-27
577 A sister lineage of the Mycobacterium tuberculosis complex discovered in the African Great Lakes region
Semuto Ngabonziza, J. C.; Loiseau, C.; Marceau, M.; Jouet, A.; Menardo, F.; Tzfadia, O.; Antoine, R.; Niyigena, E. B.; Mulders, W.; Fissette, K.; Diels, M.; Gaudin, C.; Duthoy, S.; Ssengooba, W.; Andre, E.; Kaswa, M. K.; Mucyo Habimana, Y.; Brites, D.; Affolabi, D.; Mazarati, J. B.; de Jong, B. C.; Rigouts, L.; Gagneux, S.; Meehan, C. J.; Supply, P. J.
10.1101/2020.01.20.912998 — microbiology — Posted on 2020-03-27
578 Antigen-presenting fibroblasts sustain anti-tumour CD4+ T cells in situ via MHCIIp-TCR and C1q-C1qbp binding.
Kerdidani, D.; Goudevenou, K.; Aerakis, E.; Verrou, K.-M.; Stamoulis, P.; Tzaferis, C.; Prados, A.; Vamvakaris, I.; Kaniaris, E.; Vachlas, K.; Sepsas, E.; Potaris, K.; Koutsopoulos, A.; Tsoumakidou, M.
10.1101/2020.03.24.005355 — immunology — Posted on 2020-03-27
580 How do invasion syndromes evolve? An experimental evolution approach using the ladybird Harmonia axyridis
Foucaud, J.; Hufbauer, R. A.; Ravigne, V.; Olazcuaga, L.; Loiseau, A.; Ausset, A.; Wang, S.; Zang, L.-S.; Lemenager, N.; Tayeh, A.; Weyna, A.; Gneux, P.; Bonnet, E.; Dreuilhe, V.; Poutout, B.; Estoup, A.; Facon, B.
10.1101/849968 — evolutionary biology — Posted on 2020-03-27
583 Diversification in evolutionary arenas -- assessment and synthesis
Nürk, N. M.; Linder, H. P.; Onstein, R. E.; Larcombe, M.; Hughes, C. E.; Pineiro Fernandez, L.; Schlüter, P. M.; Valente, L. M.; Beierkuhnlein, C.; Cutts, V.; Donoghue, M. J.; Edwards, E. J.; Field, R.; Flantua, S. G. A.; Higgins, S. I.; Jentsch, A.; Liede-Schumann, S.; Pirie, M. D.
10.1101/636803 — evolutionary biology — Posted on 2020-03-27
584 Accuracy and Reproducibility of Somatic Point Mutation Calling in Clinical-Type Targeted Sequencing Data
Karimnezhad, A.; Palidwor, G. A.; Thavorn, K.; Stewart, D. J.; Campbell, P. A.; Lo, B.; Perkins, T. J.
10.1101/2019.12.31.891952 — bioinformatics — Posted on 2020-03-27
590 Transcriptome-Wide Combinatorial RNA Structure Probing in Living Cells
Chan, D.; Feng, C.; England, W.; Wyman, D.; Flynn, R.; Wang, X.; Shi, Y.; Mortazavi, A.; Spitale, R.
10.1101/2020.03.24.006866 — biochemistry — Posted on 2020-03-27
591 The LRRC8A:C Heteromeric Channel Is a cGAMP Transporter and the Dominant cGAMP Importer in Human Vasculature Cells
Lahey, L. J.; Wen, X.; Mardjuki, R. E.; Böhnert, V.; Hess, G. T.; Ritchie, C.; Carozza, J. A.; Maduke, M.; Bassik, M. C.; Li, L.
10.1101/2020.02.13.948273 — biochemistry — Posted on 2020-03-27
592 Single-cell transcriptome analysis reveals cell-cell communication and thyrocyte diversity in the zebrafish thyroid gland
Gillotay, P.; Shankar, M. P.; Haerlingen, B.; Eski, S. E.; Pozo-Morales, M.; Suner, I. G.; Reinhardt, S.; Kraenkel, A.; Blaesche, J.; Petzold, A.; Ninov, N.; Kesavan, G.; Lange, C.; Brand, M.; Detours, V.; Costagliola, S.; Singh, S. P.
10.1101/2020.01.13.891630 — developmental biology — Posted on 2020-03-27
593 Learning 2-in-1: towards integrated EEG-fMRI-neurofeedback
Perronnet, L.; Lecuyer, A.; Mano, M.; Fleury, M.; Lioi, G.; Cury, C.; Clerc, M.; Lotte, F.; Barillot, C.
10.1101/397729 — bioengineering — Posted on 2020-03-27
594 Distinct extracellular-matrix remodeling events precede symptoms of inflammation
Shimshoni, E.; Adir, I.; Afik, R.; Solomonov, I.; Shenoy, A.; Adler, M.; Puricelli, L.; Ghini, V.; Mouhadeb, O.; Gluck, N.; Fishman, S.; Werner, L.; Shouval, D. S.; Varol, C.; Podesta, A.; Turano, P.; Geiger, T.; Milani, P.; Luchinat, C.; Alon, U.; Sagi, I.
10.1101/665653 — immunology — Posted on 2020-03-27
595 Non-parametric polygenic risk prediction using partitioned GWAS summary statistics
Chun, S.; Imakaev, M.; Hui, D.; Patsopoulos, N. A.; Neale, B. M.; Kathiresan, S.; Stitziel, N. O.; Sunyaev, S. R.
10.1101/370064 — genetics — Posted on 2020-03-27
598 Identification of genes required for enzalutamide resistance in castration-resistant prostate cancer cells in vitro
Kohrt, S. E.; Awadallah, W. N.; Phillips, R. A.; Case, T. C.; Jin, R.; Nanda, J. S.; Yu, X.; Clark, P. E.; Yi, Y.; Matusik, R. J.; Anderson, P. D.; Grabowska, M. M.
10.1101/2020.03.27.011825 — cancer biology — Posted on 2020-03-27
599 Markerless tracking of an entire insect colony
Bozek, K.; Hebert, L.; Portugal, Y. D.; Stephens, G. J.
10.1101/2020.03.26.007302 — bioinformatics — Posted on 2020-03-27
601 Inflated citations and metrics of journals discontinued from Scopus for publication concerns: the GhoS(t)copus Project
Cortegiani, A.; Ippolito, M.; Ingoglia, G.; Manca, A.; Cugusi, L.; Severin, A.; Strinzel, M.; Panzarella, V.; Campisi, G.; Lalu, M.; Einav, S.; Moher, D.; Giarratano, A.
10.1101/2020.03.26.007435 — scientific communication and education — Posted on 2020-03-27
602 Burkholderia pseudomallei clinical isolates are highly susceptible in vitro to cefiderocol, a novel siderophore cephalosporin
Burnard, D.; Robertson, G.; Henderson, A.; Falconer, C.; Bauer, M.; Cottrell, K.; Gassiep, I.; Norton, R.; Paterson, D. L.; Harris, P. N. A.
10.1101/2020.03.26.009134 — microbiology — Posted on 2020-03-27
603 DeeReCT-APA: Prediction of Alternative Polyadenylation Site Usage Through Deep Learning
Li, Z.; Li, Y.; Zhang, B.; Li, Y.; Long, Y.; Zhou, J.; Zou, X.; Zhang, M.; Hu, Y.; Chen, W.; Gao, X.
10.1101/2020.03.26.009373 — bioinformatics — Posted on 2020-03-27
606 Anaerobic metabolism of Foraminifera thriving below the seafloor
Orsi, W. D.; Morard, R.; Vuillemin, A.; Eitel, M.; Woerheide, G.; Milucka, J.; Kucera, M.
10.1101/2020.03.26.009324 — microbiology — Posted on 2020-03-27
608 Convective forces increase rostral delivery of intrathecal antisense oligonucleotides in the cynomolgus monkey nervous system
Sullivan, J. M.; Mazur, C.; Wolf, D. A.; Horky, L.; Currier, N.; Fitzsimmons, B.; Hesterman, J.; Pauplis, R.; Haller, S.; Powers, B.; Tayefeh, L.; DeBrosse-Serra, B.; Hoppin, J.; Kordasiewicz, H.; Swayze, E. E.; Verma, A.
10.1101/2020.03.26.008425 — neuroscience — Posted on 2020-03-27
612 In-cell destabilization of a homo-dimeric protein complex detected by DEER spectroscopy
Yang, Y.; Chen, S.-N.; Yang, F.; Li, X. Y.; Feintuch, A.; Su, X.-C.; Goldfarb, D.
10.1101/2020.03.27.011510 — biophysics — Posted on 2020-03-27
614 Membrane lipid requirements of the lysine transporter Lyp1 from Saccharomyces cerevisiae
Poolman, B.; van't Klooster, J.; Cheng, T.-Y.; Sikkema, H. R.; Jeucken, A.; Moody, D. B.
10.1101/2020.03.27.011031 — biochemistry — Posted on 2020-03-27
615 Ancestral function of Inhibitors-of-kappaB regulates Caenorhabditis elegans development
Brena, D.; Bertran, J.; Porta-de-la-Riva, M.; Guillen, Y.; Cornes, E.; Kukhtar, D.; Campos-Vicens, L.; Fernandez, L.; Pecharroman, I.; Garcia-Lopez, A.; Islam, K.; Marruecos, L.; Bigas, A.; Ceron, J.; Espinosa, L.
10.1101/2020.03.26.010355 — developmental biology — Posted on 2020-03-27
619 Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment
Lillebostad, P. A. G.; Raasakka, A.; Hjellbrekke, S. J.; Patil, S.; Rostbo, T.; Hollas, H.; Sakya, S. A.; Szigetvari, P. D.; Vedeler, A.; Kursula, P.
10.1101/2020.03.27.011445 — biochemistry — Posted on 2020-03-27
621 Accurate Identification of SARS-CoV-2 from Viral Genome Sequences using Deep Learning
Lopez-Rincon, A.; Tonda, A.; Mendoza-Maldonado, L.; Claassen, E.; Garssen, J.; Kraneveld, A. D.
10.1101/2020.03.13.990242 — bioinformatics — Posted on 2020-03-27
622 A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
Gordon, D. E.; Jang, G. M.; Bouhaddou, M.; Xu, J.; Obernier, K.; O'Meara, M. J.; Guo, J. Z.; Swaney, D. L.; Tummino, T. A.; Huttenhain, R.; Kaake, R. M.; Richards, A. L.; Tutuncuoglu, B.; Foussard, H.; Batra, J.; Haas, K.; Modak, M.; Kim, M.; Haas, P.; Polacco, B. J.; Braberg, H.; Fabius, J. M.; Eckhardt, M.; Soucheray, M.; Bennett, M. J.; Cakir, M.; McGregor, M. J.; Li, Q.; Naing, Z. Z. C.; Zhou, Y.; Peng, S.; Kirby, I. T.; Melnyk, J. E.; Chorba, J. S.; Lou, K.; Dai, S. A.; Shen, W.; Shi, Y.; Zhang, Z.; Barrio-Hernandez, I.; Memon, D.; Hernandez-Armenta, C.; Mathy, C. J. P.; Perica, T.; Pilla
10.1101/2020.03.22.002386 — systems biology — Posted on 2020-03-27
624 In-Silico evidence for two receptors based strategy of SARS-CoV-2
Milanetti, E.; Miotto, M.; Di Rienzo, L.; Monti, M.; Gosti, G.; Ruocco, G.
10.1101/2020.03.24.006197 — biophysics — Posted on 2020-03-27
628 Medicago truncatula Yellow Stripe-Like7 encodes a peptide transporter required for symbiotic nitrogen fixation
Castro-Rodriguez, R.; Reguera, M.; Escudero, V.; Gil-Diez, P.; Quintana, J.; Prieto, R. I.; Kumar, R. K.; Brear, E.; Grillet, L.; Wen, J.; Mysore, K. S.; Walker, E. L.; Smith, P. M.; Imperial, J.; Gonzalez-Guerrero, M.
10.1101/2020.03.26.009159 — plant biology — Posted on 2020-03-27
630 Topoisomerase III-beta is required for efficient replication of positive-sense RNA viruses
Prasanth, K. R.; Hirano, M.; Fagg, W. S.; McAnarney, E.; Chan, S.; Xie, X.; Hage, A.; Pietzsch, C.; Bukreyev, A.; Rajsbaum, R.; Shi, P.-Y.; Bedford, M.; Bradrick, S.; Menachery, V. D.; Garcia-Blanco, M. A.
10.1101/2020.03.24.005900 — microbiology — Posted on 2020-03-27
644 SRRF 'n' TIRF - FCS: Simultaneous spatiotemporal super-resolution microscopy
Sankaran, J.; Balasubramanian, H.; Tang, W. H.; Ng, X. W.; Röllin, A.; Wohland, T.
10.1101/2020.02.26.965905 — biophysics — Posted on 2020-03-27
645 Transcriptional output, cell types densities and normalization in spatial transcriptomics
Saiselet, M.; Rodrigues-Vitoria, J.; Tourneur, A.; Craciun, L.; Spinette, A.; Larsimont, D.; Andry, G.; Lundeberg, J.; Maenhaut, C.; Detours, V.
10.1101/503870 — genomics — Posted on 2020-03-27
646 Live imaging defines the dynamics and molecular basis of in vivo mitophagy
Wrighton, P. J.; Shwartz, A.; Heo, J.-M.; Quenzer, E. D.; LaBella, K. A.; Harper, J. W.; Goessling, W.
10.1101/2020.03.26.010405 — cell biology — Posted on 2020-03-27
647 mir-21 is associated with inactive low molecular weight Argonaute complexes in thyroid cancer cell lines
Powell, B. H.; Turchinovich, A.; Wang, Y.; Liao, Z.; Aasif Dar, M.; La Rocca, G.; Umanah, G. E.; Zeiger, M. A.; Umbricht, C. B.; Witwer, K. W.
10.1101/2020.03.24.006072 — molecular biology — Posted on 2020-03-26
648 Cross-Cancer Evaluation of Polygenic Risk Scores for 17 Cancer Types in Two Large Cohorts
Graff, R. E.; Cavazos, T. B.; Thai, K. K.; Kachuri, L.; Rashkin, S. R.; Hoffman, J. D.; Alexeeff, S. E.; Blatchins, M.; Meyers, T. J.; Leong, L.; Tai, C. G.; Emami, N. C.; Corley, D. A.; Kushi, L. H.; Ziv, E.; Van Den Eeden, S. K.; Jorgenson, E.; Hoffmann, T. J.; Habel, L. A.; Witte, J. S.; Sakoda, L. C.
10.1101/2020.01.18.911578 — genetics — Posted on 2020-03-26
651 CDeep3M-Preview: Online segmentation using the deep neural network model zoo
Haberl, M. G.; Wong, W.; Penticoff, S.; Je, J.; Madany, M.; Borchardt, A.; Boassa, D.; Peltier, S.; Ellisman, M. H.
10.1101/2020.03.26.010660 — neuroscience — Posted on 2020-03-26
652 Gamma-rhythmic input causes spike output
Lewis, C. M.; Ni, J.; Wunderle, T.; Jendritza, P.; Diester, I.; Fries, P.
10.1101/2020.03.26.010678 — neuroscience — Posted on 2020-03-26
653 Identifying optimal working points of individual Virtual Brains: A large-scale brain network modelling study
Triebkorn, P.; Zimmermann, J.; Stefanovski, L.; Roy, D.; Solodkin, A.; Jirsa, V.; Deco, G.; Breakspear, M.; McIntosh, A. R.; Ritter, P.
10.1101/2020.03.26.009795 — neuroscience — Posted on 2020-03-26
656 Universal and taxon-specific trends in protein sequences as a function of age
James, J. E.; Willis, S. M.; Nelson, P. G.; Weibel, C.; Kosinski, L. J.; Masel, J.
10.1101/2020.03.26.010728 — evolutionary biology — Posted on 2020-03-26
657 The potential SARS-CoV-2 entry inhibitor
Lung, J.; Lin, Y.-S.; Yang, Y.-H.; Chou, Y.-L.; Chang, G.-H.; Tsai, M.-S.; Hsu, C.-M.; Yeh, R.-A.; Shu, L.-H.; Cheng, Y.-C.; Te Liu, H.; Wu, C.-Y.
10.1101/2020.03.26.009803 — bioinformatics — Posted on 2020-03-26
662 Multiple phase-variable mechanisms, including capsular polysaccharides, modify bacteriophage susceptibility in Bacteroides thetaiotaomicron
Porter, N. T.; Hryckowian, A. J.; Merrill, B. D.; Fuentes, J. J.; Gardner, J. O.; Glowacki, R. W. P.; Singh, S.; Crawford, R. D.; Snitkin, E. S.; Sonnenburg, J. L.; Martens, E. C.
10.1101/521070 — microbiology — Posted on 2020-03-26
663 Experimental erosion of microbial diversity decreases soil CH4 consumption rates
Schnyder, E.; Bodelier, P. L. E.; Hartmann, M.; Henneberger, R.; Niklaus, P. A.
10.1101/2020.03.24.003657 — ecology — Posted on 2020-03-26
665 Capsid lattice destabilization leads to premature loss of the viral genome and integrase enzyme during HIV-1 infection
Eschbach, J. E.; Elliott, J. L.; Li, W.; Zadrozny, K. K.; Davis, K.; Mohammed, S.; Lawson, D. Q.; Pornillos, O.; Engelman, A. N.; Kutluay, S.
10.1101/2020.03.26.009902 — microbiology — Posted on 2020-03-26
666 Sugar feeding patterns of New York Aedes albopictus mosquitoes are affected by environmental dryness, flowers, and host seeking
Fikrig, K.; Peck, S.; Deckerman, P.; Dang, S.; St Fleur, K.; Goldsmith, H.; Qu, S.; Rosenthal, H.; Harrington, L. C.
10.1101/2020.03.26.009779 — ecology — Posted on 2020-03-26
667 Role for the flagellum attachment zone in the resolution of cell membrane morphogenesis during Leishmania cell division
Sunter, J.; Halliday, C.; Yanase, R.; Catta-Preta, C. M. C.; Moreira-Leite, F.; Myskova, J.; Pruzinova, K.; Volf, P.; Mottram, J. C.
10.1101/2020.03.26.009928 — cell biology — Posted on 2020-03-26
669 Crystal structure of β-L-arabinobiosidase belonging to glycoside hydrolase family 121
Saito, K.; Viborg, A. H.; Sakamoto, S.; Arakawa, T.; Yamada, C.; Fujita, K.; Fushinobu, S.
10.1101/2020.03.26.009860 — biochemistry — Posted on 2020-03-26
670 Changes in the blood plasma lipidome associated with response to atypical antipsychotic treatments in schizophrenia
de Almeida, V.; Alexandrino, G. L.; Aquino, A.; Gomes, A. F.; Murgu, M.; Guest, P. C.; Steiner, J.; de Souza, D. M.
10.1101/2020.03.25.008474 — biochemistry — Posted on 2020-03-26
676 Deficient ER acetyl-CoA import in acinar cells leads to chronic pancreatitis
Cooley, M.; Thomas, D.; Deans, K.; Peng, Y.; Lugea, A.; Pandol, S.; Puglielli, L.; Groblewski, G.
10.1101/2020.03.25.008557 — pathology — Posted on 2020-03-26
678 Resolving fate and transcriptome of hematopoietic stem cell clones
Pei, W.; Shang, F.; Wang, X.; Fanti, A.-K.; Greco, A.; Busch, K.; Klapproth, K.; Zhang, Q.; Quedenau, C.; Sauer, S.; Feyerabend, T. B.; Hofer, T.; Rodewald, H.-R.
10.1101/2020.03.25.008433 — immunology — Posted on 2020-03-26
679 Establishment of a pancreatic adenocarcinoma molecular gradient (PAMG) that predicts the clinical outcome of pancreatic cancer
Nicolle, R.; Blum, Y.; Duconseil, P.; Vanbrugghe, C.; Brandone, N.; Poizat, F.; Roques, J.; Bigonnet, M.; Gayet, O.; Rubis, M.; Elarouci, N.; Armenoult, L.; Ayadi, M.; Dereynies, A.; Giovannini, M.; Grandval, P.; Garcia, S.; Canivet, C.; Cros, J.; Bournet, B.; Buscail, L.; Moutardier, V.; Gilabert, M.; Iovanna, J. L.; Dusetti, N. J.
10.1101/2020.03.25.998138 — cancer biology — Posted on 2020-03-26
680 CD19-targeting CAR T cells potently redirected to kill solid tumor cells
Ambrose, C.; Su, L.; Wu, L.; Dufort, F. J.; Stanford, T.; Birt, A.; Hackel, B. J.; Hombach, A. A.; Abken, H.; Lobb, R. R.; Rennert, P. D.
10.1101/2020.03.25.007658 — cancer biology — Posted on 2020-03-26
683 Microbial and autoantibody immunogenic repertoires in TIF1γ autoantibody positive dermatomyositis
Megremis, S.; Walker, T.; He, X.; O'Sullivan, J.; Ollier, W. E. R.; Chinoy, H.; Pendleton, N.; Payton, A.; Hampson, L.; Hampson, I.; Lamb, J.
10.1101/2020.03.25.007534 — immunology — Posted on 2020-03-26
684 SCOUT: Single-cell outlier analysis in cancer
Onzi, G. R.; Faccioni, J. L.; Alvarado, A. G.; Bracco, P. A.; Kornblum, H. L.; Lenz, G.
10.1101/2020.03.25.007518 — bioinformatics — Posted on 2020-03-26
688 Forest condition in the Congo Basin for the assessment of ecosystem conservation status
Shapiro, A.; Grantham, H.; Aguilar-Amuchastegui, N.; Murray, N. J.; Gond, V.; Bonfils, D.; Rickenback, O.
10.1101/2020.03.25.008110 — ecology — Posted on 2020-03-26
689 Structural basis of ethnic-specific variants of PAX4 associated with type 2 diabetes
Hosoe, J.; Suzuki, K.; Kato, T.; Okada, Y.; Horikoshi, M.; Shojima, N.; Yamauchi, T.; Kadowaki, T.
10.1101/2020.03.24.006254 — genetics — Posted on 2020-03-26
691 Cell type-specific histone acetylation profiling of Alzheimer's Disease subjects and integration with genetics
Ramamurthy, E.; Welch, G.; Cheng, J.; Yuan, Y.; Gunsalus, L.; Bennett, D. A.; Tsai, L.-H.; Pfenning, A.
10.1101/2020.03.26.010330 — genetics — Posted on 2020-03-26
692 Protein QTL analysis of IGF-I and its binding proteins provides insights into growth biology
Bartell, E. R.; Fujimoto, M.; Khoury, J. C.; Khoury, P. R.; Vedantam, S.; Hirschhorn, J.; Dauber, A.
10.1101/2020.03.25.007724 — genetics — Posted on 2020-03-26
693 Splicing impact of deep exonic missense variants in CAPN3 explored systematically by minigene functional assay
Dionnet, E.; Defour, A.; Da Silva, N.; Salvi, A.; Levy, N.; Krahn, M.; Bartoli, M.; Puppo, F.; Gorokhova, S.
10.1101/2020.03.26.009332 — genetics — Posted on 2020-03-26
694 A rare MHC haplotype confers selective advantage in a free-living ruminant
Huang, W.; Dicks, k. L.; Hadfield, J. D.; Johnston, S. E.; Ballingall, K. T.; Pemberton, J. M.
10.1101/2020.03.25.008565 — evolutionary biology — Posted on 2020-03-26
696 Discriminating changes to protein structure using PTAD conjugation to tyrosine
Moinpour, M.; Barker, N. K.; Guzman, L. E.; Jewett, J. C.; Langlais, P. R.; Schwartz, J. C.
10.1101/2020.02.04.934406 — biochemistry — Posted on 2020-03-26
700 Summer drought decreases the predictability of local extinctions in a butterfly metapopulation
van Bergen, E.; Dallas, T.; DiLeo, M. F.; Kahilainen, A.; Mattila, A. L. K.; Luoto, M.; Saastamoinen, M.
10.1101/863795 — ecology — Posted on 2020-03-26
701 The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double strand break repair
Huang, T.; Yuan, S.; Gao, L.; Li, M.; Yu, X.; Zhang, J.; Yin, Y.; Liu, C.; Zhang, C.; Lu, G.; Li, W.; Liu, J.; Chen, Z.-J.; Liu, H.
10.1101/836023 — developmental biology — Posted on 2020-03-26
702 MAPK-induced miR-29 targets MAFG and suppresses melanoma progression
Vera, O.; Bok, I.; Jasani, N.; Nakamura, K.; Xu, X.; Mecozzi, N.; Karreth, F. A.
10.1101/2020.01.27.922153 — cancer biology — Posted on 2020-03-26
703 Genome-scale Model Constrained by Proteomics Reveals Metabolic Changes in Streptomyces coelicolor M1152 Compared to M145
Sulheim, S.; Kumelj, T.; van Dissel, D.; Salehzadeh-Yazdi, A.; Du, C.; van Wezel, G. P.; Nieselt, K.; Almaas, E.; Wentzel, A.; Kerkhoven, E. J.
10.1101/796722 — systems biology — Posted on 2020-03-26
704 Optogenetic control of gut bacterial metabolism to promote longevity
Hartsough, L. A.; Kotlajich, M. V.; Han, B.; Lin, C.-C. J.; Gambill, L.; Wang, M. C.; Tabor, J. J.
10.1101/2020.02.25.964866 — synthetic biology — Posted on 2020-03-26
708 Sources of Off-Target Effects of Vagus Nerve Stimulation Using the Helical Clinical Lead in Domestic Pigs
Nicolai, E. N.; Settell, M. L.; Knudsen, B. E.; McConico, A. L.; Gosink, B. A.; Trevathan, J. K.; Baumgart, I. W.; Ross, E. K.; Pelot, N. A.; Grill, W. M.; Gustafson, K. J.; Shoffstall, A. J.; Williams, J. C.; Ludwig, K. A.
10.1101/2020.01.15.907246 — neuroscience — Posted on 2020-03-26
716 Potential evolutionary body size reduction in a Malagasy primate (Propithecus verreauxi) in response to human size-selective hunting pressure
Sullivan, A. P.; Godfrey, L. R.; Lawler, R. R.; Randrianatoandro, H.; Eccles, L.; Culleton, B.; Ryan, T. M.; Perry, G. H.
10.1101/2020.03.23.004234 — evolutionary biology — Posted on 2020-03-26
720 Spatiotemporal dissection of the cell cycle with single-cell proteogenomics
Mahdessian, D.; Cesnik, A. J.; Gnann, C.; Danielsson, F.; Akesson, L.; Arif, M.; Zhang, C.; Schutten, R.; Backstrom, A.; Thul, P.; Cho, N.; Carja, O.; Uhen, M.; Mardinoglu, A.; Stadler, C.; Lindskog, C.; Ayoglu, B.; Leonetti, M.; Ponten, F.; Sullivan, D.; Lundberg, E.
10.1101/543231 — cell biology — Posted on 2020-03-26
721 Ab-Ligity: Identifying sequence-dissimilar antibodies that bind to the same epitope
Wong, W. K.; Robinson, S. A.; Bujotzek, A.; Georges, G.; Lewis, A. P.; Shi, J.; Snowden, J.; Taddese, B.; Deane, C.
10.1101/2020.03.24.004051 — bioinformatics — Posted on 2020-03-26
724 Different theta frameworks coexist in the hippocampus and are coordinated during memory-guided exploration and novelty detection
Lopez-Madrona, V. J.; Perez-Montoyo, E.; Alvarez-Salvado, E.; Moratal, D.; Herreras, O.; Pereda, E.; Mirasso, C. R.; Canals, S.
10.1101/418434 — neuroscience — Posted on 2020-03-26
725 Transient uterine hypercontractility causes fetal cerebral oxidative stress and enduring mitochondrial and behavioral abnormalities in adolescent male rat offspring
Palanisamy, A.; Giri, T.; Jiang, J.; Bice, A.; Quirk, J. D.; Conyers, S.; Maloney, S.; Raghuraman, N.; Bauer, A. Q.; Garbow, J. R.; Wozniak, D. F.
10.1101/689927 — neuroscience — Posted on 2020-03-26
728 The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis
Carrat, G. R.; Haythorne, E.; Tomas, A.; Haataja, L.; Mueller, A.; Arvan, P.; Piunti, A.; Cheng, K.; Huang, M.; Pullen, T.; Georgiadou, E.; Stylianides, T.; Amirruddin, N. S.; Salem, V.; Distaso, W.; Cakebread, A.; Heesom, K. J.; Lewis, P. A.; Hodson, D.; Briant, L. J.; Fung, A. C. H.; Sessions, R. B.; Alpy, F.; Kong, A. P. S.; Benke, P. I.; Torta, F.; Teo, A. K. K.; Leclerc, I.; Solimena, M.; Wigley, D. B.; Rutter, G. A.
10.1101/2020.03.25.007286 — cell biology — Posted on 2020-03-26
732 Direct visualization and characterization of the human zona incerta and surrounding structures
Lau, J. C.; Xiao, Y.; Haast, R. A.; Gilmore, G.; Uludag, K.; MacDougall, K. W.; Menon, R. R.; Parrent, A. G.; Peters, T. M.; Khan, A. R.
10.1101/2020.03.25.008318 — neuroscience — Posted on 2020-03-26
736 Exploiting prior knowledge about biological macromolecules in cryo-EM structure determination
Kimanius, D.; Zickert, G.; Nakane, T.; Adler, J.; Lunz, S.; Schonlieb, C.-B.; Oktem, O.; Scheres, S.
10.1101/2020.03.25.007914 — molecular biology — Posted on 2020-03-26
748 Spatiotemporal patterns of high-frequency activity (80-170 Hz) in long-term intracranial EEG
Chen, Z.; Grayden, D. B.; Burkitt, A. N.; Seneviratne, U.; D'Souza, W. J.; French, C.; Karoly, P. J.; Dell, K.; Cook, M. J.; Maturana, M. I.
10.1101/2020.03.26.999425 — neuroscience — Posted on 2020-03-26
750 Top-down coordination of local cortical state during selective attention
van Kempen, J.; Gieselmann, M. A.; Boyd, M.; Steinmetz, N. A.; Moore, T.; Engel, T.; Thiele, A.
10.1101/2020.03.26.009365 — neuroscience — Posted on 2020-03-26
751 A Novel Method for Calculating Beta Band Burst Durations in Parkinson's Disease Using a Physiological Baseline
Anderson, R. W.; Neuville, R. S.; Kehnemouyi, Y. M.; Anidi, C. M.; Petrucci, M. N.; Parker, J. E.; Velisar, A.; Bronte-Stewart, H. M.
10.1101/2020.03.25.008185 — neuroscience — Posted on 2020-03-26
754 POMC neurons functional heterogeneity relies on mTORC1 signaling
Saucisse, N.; Mazier, W.; Simon, V.; Binder, E.; Catania, C.; Bellocchio, L.; Romanov, R. A.; Matias, I.; Zizzari, P.; Leon, S.; Quarta, C.; Cannich, A.; Meece, K.; Gonzales, D.; Clark, S.; Becker, J. M.; Yeo, G. S. H.; Merkle, F. T.; Wardlaw, S. L.; Harkany, T.; Massa, F.; Marsicano, G.; Cota, D.
10.1101/2020.03.25.007765 — neuroscience — Posted on 2020-03-26
755 Action enhances predicted touch
Thomas, E. R.; Yon, D.; de Lange, F. P.; Press, C.
10.1101/2020.03.26.007559 — neuroscience — Posted on 2020-03-26
762 TERL: Classification of Transposable Elements by Convolutional Neural Networks
da Cruz, M. H. P.; Domingues, D. S.; Saito, P. T. M.; Paschoal, A. R.; Bugatti, P. H.
10.1101/2020.03.25.000935 — bioinformatics — Posted on 2020-03-26
764 Circulating immune cell phenotype dynamics reflect the strength of tumor-immune cell interactions in patients during immunotherapy
Griffiths, J. I.; Wallet, P.; Pflieger, L. T.; Stenehjem, D.; Liu, X.; Cosgrove, P. A.; Leggett, N. A.; McQuerry, J.; Shrestha, G.; Rossetti, M.; Sunga, G.; Moos, P. J.; Adler, F. R.; Chang, J. T.; Sharma, S.; Bild, A. H.
10.1101/2020.03.24.993923 — cancer biology — Posted on 2020-03-26
765 DDX5 targets tissue-specific RNAs to promote intestine tumorigenesis
Abbasi, N.; Long, T.; Li, Y.; Ma, E.; Yee, B. A.; Patel, P. R.; Sayed, I. M.; Varki, N.; Das, S.; Ghosh, P.; Yeo, G. W.; Huang, W. J. M.
10.1101/2020.03.25.006668 — cancer biology — Posted on 2020-03-26
766 Cancer associated talin point mutations disorganise cell adhesion and migration
Azizi, L.; Cowell, A.; Mykuliak, V. V.; Goult, B. T.; Turkki, P.; Hytonen, V. P.
10.1101/2020.03.25.008193 — cancer biology — Posted on 2020-03-26
768 Ibrutinib blocks YAP1 activation and reverses BRAFi resistance in melanoma cells
Misek, S. A.; Newbury, P. A.; Chekalin, E.; Paithankar, S.; Doseff, A. I.; Chen, B.; Gallo, K. A.; Neubig, R. R.
10.1101/2020.03.25.006916 — cancer biology — Posted on 2020-03-26
769 Effects of Controlled Dual Growth Factor Delivery on Bone Regeneration Following Composite Bone-Muscle Injury
Subbiah, R.; Cheng, A.; Ruehle, M. A.; Hettiaratchi, M. H.; Bertassoni, L. E.; Guldberg, R. E.
10.1101/2020.03.25.008813 — bioengineering — Posted on 2020-03-26
770 Chronic Interleukin-1 exposure triggers selective expansion of Cebpa-deficient multipotent hematopoietic progenitors
Higa, K. C.; Goodspeed, A.; Chavez, J. S.; Zaberezhnyy, V.; Rabe, J. L.; Tenen, D. G.; Pietras, E. M.; DeGregori, J.
10.1101/2020.03.25.008250 — cancer biology — Posted on 2020-03-26
771 Global computational alignment of tumor and cell line transcriptional profiles
Warren, A.; Jones, A.; Shibue, T.; Hahn, W. C.; Boehm, J. S.; Vazquez, F.; Tsherniak, A.; McFarland, J. M.
10.1101/2020.03.25.008342 — cancer biology — Posted on 2020-03-26
774 Bedrock radioactivity influences the rate and spectrum of mutation
Saclier, N.; Chardon, P.; Malard, F.; Konecny-Dupre, L.; Eme, D.; Bellec, A.; Breton, V.; Duret, L.; Lefebure, T.; Douady, C. J.
10.1101/2020.03.23.003616 — evolutionary biology — Posted on 2020-03-26
775 In vitro and In vivo Genetic Disease Modelling via NHEJ precise deletions using CRISPR/Cas9
Lopez-Manzaneda, S.; Ojeda-Perez, I.; Zabaleta, N.; Garcia-Torralba, A.; Alberquilla, O.; Torres, R.; Sanchez-Dominguez, R.; Torella, L.; Olivier, E.; Mountford, J.; Ramirez, J. C.; Bueren, J. A.; Gonzalez-Aseguinolaza, G.; Segovia, J. C.
10.1101/2020.03.25.007260 — bioengineering — Posted on 2020-03-26
778 A survey of rare epigenetic variation in 23,116 human genomes identifies disease-relevant epivariations and novel CGG expansions
Garg, P.; Jadhav, B.; Rodriguez, O. J.; Patel, N.; Martin-Trujillo, A.; Jain, M.; Metsu, S.; Olsen, H.; Paten, B.; Ritz, B.; Kooy, F.; Gecz, J.; Sharp, A. J.
10.1101/2020.03.25.007864 — genomics — Posted on 2020-03-26
780 Functional modeling of NMIHBA-causing PRUNE1 variants reveals a requirement for its exopolyphosphatase activity.
Nistala, H.; Dronzek, J.; Gonzaga-Jauregui, C.; Man Chim, S.; Rajamani, S.; Nuwayhid, S.; Delgado, D.; Burke, E.; Karaca, E.; Franklin, M. C.; Sarangapani, P.; Podgorski, M.; Tang, Y.; Dominguez, M. G.; Withers, M.; Deckelbaum, R. A.; Scheonherr, C. J.; Gahl, W. A.; Malicdan, M. C.; Zambrowicz, B.; Gale, N. W.; Gibbs, R. A.; Chung, W. K.; Lupski, J. R.; Economides, A. N.
10.1101/2020.03.02.973909 — genetics — Posted on 2020-03-26
781 Incorporation of a nucleoside analog maps genome repair sites in post-mitotic human neurons
Reid, D. A.; Reed, P. J.; Schlachetzki, J. C. M.; Chou, G.; Chandran, S.; Lu, A. T.; McClain, C. A.; Ooi, J. H.; Jones, J. R.; Linker, S. B.; Tsui, E. C.; Ricciardulli, A. S.; Lau, S.; Schafer, S. T.; Horvath, S.; Dixon, J. R.; Hah, N.; Glass, C. K.; Gage, F. H.
10.1101/2020.03.25.008490 — neuroscience — Posted on 2020-03-26
786 Systematic discovery of Short Linear Motifs decodes calcineurin phosphatase signaling
Wigington, C. P.; Roy, J.; Damle, N. P.; Yadav, V. K.; Blikstad, C.; Resch, E.; Wong, C. J.; Mackay, D. R.; Wang, J. T.; Krystkowiak, I.; Bradburn, D. A.; Tsekitsidou, E.; Hong, S. H.; Kaderali, M. A.; Xu, S.-l.; Stearns, T.; Gingras, A.-C.; Ullman, K. S.; Ivarsson, Y.; Davey, N. E.; Cyert, M. S.
10.1101/632547 — cell biology — Posted on 2020-03-26
787 A dynamic 6,000-year genetic history of Eurasia's Eastern Steppe
Jeong, C.; Wang, K.; Wilkin, S.; Taylor, W. T. T.; Miller, B.; Ulziibayar, S.; Stahl, R.; Chiovelli, C.; Bemmann, J. H.; Knolle, F.; Kradin, N.; Bazarov, B. A.; Miyagashev, D. A.; Konovalov, P. B.; Zhambaltarova, E.; Miller, A. V.; Haak, W.; Schiffels, S.; Krause, J.; Boivin, N.; Myagmar, E.; Hendy, J.; Warinner, C.
10.1101/2020.03.25.008078 — genomics — Posted on 2020-03-26
788 Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis
Kusnadi, E. P.; Trigos, A. S.; Cullinane, C.; Goode, D. L.; Larsson, O. S.; Devlin, J. R.; Chan, K. T.; DeSouza, D. P.; McConville, M. J.; McArthur, G. A.; Thomas, G.; Sanij, E.; Poortinga, G.; Hannan, R. D.; Hannan, K. M.; Kang, J.; Pearson, R. B.
10.1101/847723 — cancer biology — Posted on 2020-03-26
789 Potent human neutralizing antibodies elicited by SARS-CoV-2 infection
Ju, B.; Zhang, Q.; Ge, X.; Wang, R.; Yu, J.; Shan, S.; Zhou, B.; Song, S.; Tang, X.; Yu, J.; Ge, J.; Lan, J.; Yuan, J.; Wang, H.; Zhao, J.; Zhang, S.; Wang, Y.; Shi, X.; Liu, L.; Wang, X.; Zhang, Z.; Zhang, L.
10.1101/2020.03.21.990770 — immunology — Posted on 2020-03-26
790 Using structural connectivity to augment community structure in EEG functional connectivity
Glomb, K.; Mullier, E.; Carboni, M.; Rubega, M.; Iannotti, G.; Tourbier, S.; Seeber, M.; Vulliemoz, S.; Hagmann, P.
10.1101/831743 — neuroscience — Posted on 2020-03-26
791 The virulence of the Cryptococcus neoformans VNIa-5 lineage is highly plastic and associated with isolate background.
Trieu, H. P.; Thanh, T. L.; Duong, A. V.; Mai, T. N.; Huong, L. N. P.; Thwaites, G. E.; Johnson, E.; Vinh, C. N. V.; Baker, S.; Ashton, P.; Day, J. N.
10.1101/2020.02.24.962134 — microbiology — Posted on 2020-03-26
792 Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans
Hurdiss, D. L.; Drulyte, I.; Lang, Y.; Shamorkina, T. M.; Pronker, M. F.; van Kuppeveld, F. J. M.; Snijder, J.; de Groot, R. J.
10.1101/2020.03.25.998963 — microbiology — Posted on 2020-03-26
794 Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation
Devos, M.; Tanghe, G.; Gilbert, B.; Dierick, E.; Verheirstraeten, M.; Nemegeer, J.; de Reuver, R.; Lefebvre, S.; De Munck, J.; Rehwinkel, J.; Vandenabeele, P.; Declercq, W.; Maelfait, J.
10.1101/2020.03.25.007096 — immunology — Posted on 2020-03-26
795 The environmental stress response causes ribosome loss in aneuploid yeast cells.
Terhorst, A.; Sandikci, A.; Keller, A.; Whittaker, C. A.; Dunham, M. J.; Amon, A.
10.1101/2020.03.25.008540 — cell biology — Posted on 2020-03-26
797 Therapeutic genetic variation revealed in diverse Hsp104 homologs
March, Z.; Sweeney, K.; Kim, H.; Yan, X.; Castellano, L.; Jackrel, M.; Chuang, E.; Gomes, E.; Michalska, K.; Jedrzejczak, R.; Joachimiak, A.; Caldwell, K.; Caldwell, G.; Shalem, O.; Shorter, J.
10.1101/2020.03.25.008748 — biochemistry — Posted on 2020-03-26
800 Toxoplasmicidal in vitro effect of dehydroepiandrosterone on Toxoplasma gondii extracellular tachizoytes
Muniz-Hernandez, S.; Gomez-De Leon, C. T.; Luna-Nophal, A.; Dominguez-Ramirez, L.; Patron-Soberano, O. A.; Nava-Castro, K. E.; Ostoa-Saloma, P.; Morales-Montor, J.
10.1101/2020.03.23.004713 — microbiology — Posted on 2020-03-26
801 Dissecting Hes-centered transcriptional networks in neural stem cell maintenance and tumorigenesis in Drosophila
Magadi, S. S.; Voutyraki, C.; Anagnostopoulos, G.; Zacharioudaki, E.; Poutakidou, I. K.; Efraimoglou, C.; Stapountzi, M.; Theodorou, V.; Nikolaou, C.; Delidakis, C.
10.1101/2020.03.25.007187 — developmental biology — Posted on 2020-03-25
802 Regulation of caveolae through cholesterol-depletion dependent tubulation by PACSIN2/Syndapin II
Amir, A. G.; Takemura, K.; Hanawa-Suetsugu, K.; Oono-Yakura, K.; Yasuhara, K.; Kitao, A.; Suetsugu, S.
10.1101/2020.03.25.008854 — cell biology — Posted on 2020-03-25
803 In situ differentiation of iridophore crystallotypes underlies zebrafish stripe patterning
Gur, D.; Bain, E. J.; Johnson, K.; Aman, A. J.; Pasoili, A.; Flynn, J. D.; Allen, M. C.; Deheyn, D. D.; Lee, J. C.; Lippincott-Schwartz, J.; Parichy, D. M.
10.1101/2020.03.25.008664 — developmental biology — Posted on 2020-03-25
805 ER stress-mediated BK dysfunction in the DRG underlies pain in a model of multiple sclerosis
Yousuf, M. S.; Samtleben, S.; Lamothe, S. M.; Friedman, T.; Catuneanu, A.; Thorburn, K.; Desai, M.; Tenorio, G.; Schenk, G. J.; Ballanyi, K.; Kurata, H. T.; Simmen, T.; Kerr, B. J.
10.1101/2020.01.22.915546 — neuroscience — Posted on 2020-03-25
817 Insulin-like Growth Factor-1 Regulates the Mechanosensitivity of Chondrocytes by Modulating TRPV4
Trompeter, N. S.; Gardinier, J. D.; DeBarros, V. M.; Boggs, M.; Gangadharan, V.; Cain, W. J.; Hurd, L.; Duncan, R. L.
10.1101/2020.03.10.985713 — cell biology — Posted on 2020-03-25
818 Short-term exposure to intermittent hypoxia in mice leads to changes in gene expression seen in chronic pulmonary disease
Wu, G.; Lee, Y. Y.; Gulla, E. M.; Potter, A.; Kitzmiller, J.; Ruben, M. D.; Salomonis, N.; Whitsett, J. A.; Francey, L. J.; Hogenesch, J. B.; Smith, D. F.
10.1101/2020.03.06.981241 — pathology — Posted on 2020-03-25
819 Real-time suppression and amplification of neural oscillations using electrical stimulation and phase feedback
Escobar Sanabria, D.; Johnson, L. A.; Yu, Y.; Busby, Z.; Nebeck, S.; Zhang, J.; Harel, N.; Johnson, M. D.; Molnar, G. F.; Vitek, J. L.
10.1101/2020.02.09.940643 — neuroscience — Posted on 2020-03-25
823 Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation
Aslam, M. A.; Alemdehy, M. F.; Kwesi-Maliepaard, E. M.; Caganova, M.; Pardieck, I. N.; van den Brand, T.; Muhaimi, F. I.; van Welsem, T.; de Rink, I.; Song, J.-Y.; de Wit, E.; Arens, R.; Rajewsky, K.; Jacobs, H.; van Leeuwen, F.
10.1101/826370 — immunology — Posted on 2020-03-25
825 A full cycle anti-viral drug screen identifies a clinical compound against adenovirus infection
Georgi, F.; Kuttler, F.; Murer, L.; Andriasyan, V.; Witte, R.; Yakimovich, A.; Turcatti, G.; Greber, U. F.
10.1101/2020.03.24.006346 — microbiology — Posted on 2020-03-25
826 New pathogenic variants and insights into pathogenic mechanisms in GRK1-related Oguchi disease.
Poulter, J. A.; Gravett, M.; Taylor, R. L.; Fujinami, K.; De Zaeytijd, J.; Bellingham, J.; Rehman, A. U.; Hayashi, T.; Kondo, M.; Rehman, A.; Ansar, M.; Donnelly, D.; Toomes, C.; Ali, M.; UK Inherited Retinal Disease Consortium, ; Genomics England Research Consortium, ; De Baere, E.; Leroy, B. P.; Davies, N. P.; Henderson, R. H.; Webster, A. R.; Rivolta, C.; Mahroo, O. A.; Arno, G.; Black, G. C.; McKibbin, M.; Harris, S. A.; Khan, K. N.; Inglehearn, C. F.
10.1101/2020.02.20.936880 — genetics — Posted on 2020-03-25
829 Mitochondrial fission factor (MFF) is a critical regulator of peroxisome maturation
Passmore, J. B.; Carmichael, R. E.; Schrader, T. A.; Godinho, L. F.; Ferdinandusse, S.; Lismont, C.; Wang, Y.; Hacker, C.; Islinger, M.; Fransen, M.; Richards, D. M.; Freisinger, P.; Schrader, M.
10.1101/2020.01.08.898486 — cell biology — Posted on 2020-03-25
830 BiCoN: Network-constrained biclustering of patients and omics data
Lazareva, O.; Van Do, H.; Canzar, S.; Yuan, K.; Baumbach, J.; Tieri, P.; Kacprowski, T.; List, M.
10.1101/2020.01.31.926345 — bioinformatics — Posted on 2020-03-25
831 Improvement of cryo-EM maps by density modification
Terwilliger, T. C.; Ludtke, S. J.; Read, R. J.; Adams, P. D.; Afonine, P. V.
10.1101/845032 — biochemistry — Posted on 2020-03-25
835 A lipocalin mediates unidirectional haem biomineralization in malaria parasites
Matz, J. M.; Drepper, B.; Blum, T. B.; van Genderen, E.; Burrell, A.; Martin, P.; Stach, T.; Collinson, L.; Abrahams, J. P.; Matuschewski, K.; Blackman, M. J.
10.1101/2020.02.18.954289 — microbiology — Posted on 2020-03-25
836 Network-based metrics of ecological memory and resilience in lake ecosystems
Armstrong McKay, D. I.; Dyke, J. G.; Dearing, J. A.; Doncaster, C. P.; Wang, R.
10.1101/810762 — ecology — Posted on 2020-03-25
840 Pre-stress of actin cortices is important for the viscoelastic response of living cells
Cordes, A. M.; Witt, H.; Gallemi-Perez, A.; Brueckner, B. R.; Grimm, F.; Vache, M.; Oswald, T.; Floormann, D.; Lautenschlaeger, F.; Tarantola, M.; Janshoff, A.
10.1101/783613 — biophysics — Posted on 2020-03-25
843 Short and long-read genome sequencing methodologies for somatic variant detection; genomic analysis of a patient with diffuse large B-cell lymphoma
Roberts, H. E.; Lopopolo, M.; Pagnamenta, A. T.; Sharma, E.; Parkes, D.; Lonie, L.; Freeman, C.; Knight, S. J. L.; Lunter, G.; Dreau, H.; Lockstone, H.; Taylor, J. C.; Schuh, A.; Bowden, R.; Buck, D.
10.1101/2020.03.24.999870 — genetics — Posted on 2020-03-25
851 The mouse cortico-tectal projectome
Benavidez, N. L.; Bienkowski, M. S.; Khanjani, N.; Bowman, I.; Fayzullina, M.; Garcia, L.; Gao, L.; Korobkova, L.; Gou, L.; Cotter, K.; Becerra, M.; Aquino, S.; Cao, C.; Foster, N. N.; Song, M. Y.; Zhang, B.; Yamashita, S.; Zhu, M.; Lo, D.; Boesen, T.; Zingg, B.; Santarelli, A.; Wickersham, I. R.; Ascoli, G. A.; Hintiryan, H.; Dong, H.-W.
10.1101/2020.03.24.006775 — neuroscience — Posted on 2020-03-25
852 FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau fibers
Kaniyappan, S.; Tepper, K.; Biernat, J.; Chandupatla, R. R.; Huebschmann, S.; Irsen, S.; Bicher, S.; Klatt, C.; Mandelkow, E. M.; Mandelkow, E.
10.1101/2020.03.25.998831 — neuroscience — Posted on 2020-03-25
854 Sorting and cultivation of Faecalibacterium prausnitzii from fecal samples using flow cytometry in anaerobic conditions
Bellais, S.; Nehlich, M.; Duquenoy, A.; Ania, M.; van den Engh, G.; Baijer, J.; Belotserkovsky, I.; Thomas, V.
10.1101/2020.03.25.007047 — microbiology — Posted on 2020-03-25
856 Draft Genome Sequence of pyschrotolerant Clostridium sp. M14 Isolated from Spoiled Uncooked Venison.
Palevich, N.; Palevich, F. P.; Maclean, P.; Jauregui, R.; Altermann, E.; Mills, J.; Brightwell, G.
10.1101/2020.03.24.006783 — microbiology — Posted on 2020-03-25
857 scRNA-seq reveals ACE2 and TMPRSS2 expression in TROP2+ Liver Progenitor Cells: Implications in COVID-19 associated Liver Dysfunction
Seow, J. J. W.; Pai, R.; Mishra, A.; Shepherdson, E.; Lim, T. K. H.; Goh, B. K. P.; Chan, J. K.; Chow, P. K.; Ginhoux, F.; DasGupta, R.; Sharma, A.
10.1101/2020.03.23.002832 — genomics — Posted on 2020-03-25
858 Physical confinement impacts cellular phenotype within living materials
Priks, H.; Butelmann, T.; Illarionov, A.; Johnston, T. G.; Fellin, C.; Tamm, T.; Nelson, A.; Kumar, R.; Lahtvee, P.-J.
10.1101/2020.03.25.004887 — bioengineering — Posted on 2020-03-25
859 Altered specificity of 15-LOX-1 in the biosynthesis of 7S,14S-diHDHA implicates 15-LOX-2 in biosynthesis of resolvin D5
Perry, S. C.; Kalyanaraman, C.; Tourdot, B. E.; Conrad, W. S.; Akinkugbe, O.; Freedman, J. C.; Holinstat, M.; Jacobson, M. P.; Holman, T. R.
10.1101/2020.03.25.008573 — biochemistry — Posted on 2020-03-25
862 Swine Promyelocytic Leukemia Isoform II Inhibits Pseudorabies Virus Infection by Suppressing Viral Gene Transcription in PML-NBs
Yu, C.-l.; Xu, A.-t.; Lang, Y.; Qin, C.; Yuan, X.; Feng, W.-h.; Wang, M.-d.; Gao, C.; Chen, J.-w.; Zhang, R.; Tang, J.
10.1101/2020.03.23.004697 — immunology — Posted on 2020-03-25
866 Noxious effects of cell surface display glutamate sensors on plant growth and development
Castro-Rodriguez, V.; Kleist, T. J.; Gappel, N. M.; Okumoto, S.; Machado, M.; Denyer, T.; Timmermans, M. C. P.; Frommer, W. B.; Wudick, M. M.
10.1101/2020.03.24.005223 — plant biology — Posted on 2020-03-25
872 EASE: EM-Assisted Source Extraction from calcium imaging data
Zhou, P.; Reimer, J.; Zhou, D.; Pasarkar, A.; Kinsella, I. A.; Froudarakis, E.; Yatsenko, D.; Fahey, P.; Bodor, A.; Buchanan, J.; Bumbarger, D. J.; Mahalingam, G.; Torres, R.; Dorkenwald, S.; Ih, D.; Lee, K.; Liu, R.; Macrina, T.; Silversmith, W.; Wu, J.; Wong, W.; Macarico da Costa, N.; Reid, R. C.; Tolias, A.; Paninski, L.
10.1101/2020.03.25.007468 — neuroscience — Posted on 2020-03-25
875 Multiple known and a novel parvovirus associated with an outbreak of feline diarrhea and vomiting
Li, Y.; Gordon, E.; Idle, A.; Altan, E.; Seguin, M. A.; Estrada, M.; Deng, X.; Delwart, E.
10.1101/2020.03.24.005876 — microbiology — Posted on 2020-03-25
876 Evidence for a growth zone for deep subsurface microbial clades in near-surface anoxic sediments
Lloyd, K. G.; Bird, J. T.; Buongiorno, J.; Deas, E.; Kevorkian, R.; Noordhoek, T.; Rosalsky, J.; Roy, T.
10.1101/2020.03.24.005512 — microbiology — Posted on 2020-03-25
878 The length of lipoteichoic acid polymers controls Staphylococcus aureus cell size and envelope integrity
Hesser, A.; Matano, L. M.; Vickery, C. R.; Wood, B. M.; Santiago, A. G.; Morris, H. G.; Do, T.; Losick, R.; Walker, S.
10.1101/2020.03.23.004671 — microbiology — Posted on 2020-03-25
880 Antigen-presenting fibroblasts sustain anti-tumour CD4+ T cells in situ via MHCIIp-TCR and C1q-C1qbp binding.
Kerdidani, D.; Goudevenou, K.; Aerakis, E.; Verrou, K.-M.; Stamoulis, P.; Tzaferis, C.; Prados, A.; Vamvakaris, G.; Kaniaris, E.; Vachlas, K.; Sepsas, E.; Potaris, K.; Koutsopoulos, A.; Tsoumakidou, M.
10.1101/2020.03.24.005355 — immunology — Posted on 2020-03-25
881 Analysis of Serologic Cross-Reactivity Between Common Human Coronaviruses and SARS-CoV-2 Using Coronavirus Antigen Microarray
Khan, S.; Nakajima, R.; Jain, A.; de Assis, R. R.; Jasinskas, A.; Obiero, J. M.; Adenaiye, O.; Tai, S.; Hong, F.; Milton, D. K.; Davies, H.; Felgner, P. L.; Prometheus Study Group,
10.1101/2020.03.24.006544 — immunology — Posted on 2020-03-25
882 Severe and multifaceted systemic immunosuppression caused by experimental cancers of the central nervous system requires release of non-steroid soluble mediators
Ayasoufi, K.; Pfaller, C. K.; Evgin, L.; Khadka, R. H.; Tritz, Z. P.; Goddery, E. N.; Fain, C. E.; Yokanovich, L. T.; Himes, B. T.; Jin, F.; Zheng, J.; Schuelke, M. R.; Hansen, M. J.; Tung, W.; Pease, L. R.; Vile, R. G.; Johnson, A. J.
10.1101/2020.03.24.006825 — immunology — Posted on 2020-03-25
883 Multiple loci linked to inversions are associated with eye size variation in species of the Drosophila virilis phylad
Reis, M.; Wiegleb, G.; Claude, J.; Lata, R.; Horchler, B.; Ha, N.-T.; Reimer, C.; Vieira, C. P.; Vieira, J.; Posnien, N.
10.1101/2020.03.24.005413 — evolutionary biology — Posted on 2020-03-25
885 Conformational states of the cytoprotective protein Bcl-xL
Ryzhov, P.; Tian, Y.; Yao, Y.; Bobkov, A. A.; Im, W.; Marassi, F. M.
10.1101/2020.03.25.007740 — biophysics — Posted on 2020-03-25
886 Quality control of HLA-DR molecules by the lysosomal aspartyl protease, cathepsin D
Shah, N.; McDonald, S.; Parker, C. T. A.; Robinson, R. W. M.; Oomatia, A.; De Riva, A.; Deery, M. J.; Mellins, E. D.; Busch, R.
10.1101/2020.03.25.004101 — biochemistry — Posted on 2020-03-25
892 Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans
Hurdiss, D. L.; Drulyte, I.; Lang, Y.; Shamorkina, T. M.; Pronker, M. F.; van Kuppeveld, F. J. M.; Snijder, J.; de Groot, R. J.
10.1101/2020.03.25.998963 — microbiology — Posted on 2020-03-25
895 Capsular polysaccharides cross-regulation modulates Bacteroides thetaiotaomicron biofilm formation
BECHON, N.; MIHAJLOVIC, J.; VENDRELL-FERNANDEZ, S.; CHAIN, F.; LANGELLA, P.; BELOIN, C.; GHIGO, J.-M.
10.1101/2020.03.25.005728 — microbiology — Posted on 2020-03-25
898 Are there Physical Linkages between Genes that have Synergistic Fitness Effects?
Byrnes, J. F.; Sherwin, W.; Goldys, B.; Murray, J.; Tanaka, M.; Bellanto, A.; Cayetano, L.
10.1101/2020.03.23.004630 — evolutionary biology — Posted on 2020-03-25
899 Potential evolutionary body size reduction in a Malagasy primate (Propithecus verreauxi) in response to human size-selective hunting pressure
Sullivan, A. P.; Godfrey, L. R.; Lawler, R. R.; Randrianatoandro, H.; Eccles, L.; Culleton, B.; Ryan, T. M.; Perry, G. H.
10.1101/2020.03.23.004234 — evolutionary biology — Posted on 2020-03-25
902 FSD1: a plastidial, nuclear and cytoplasmic enzyme relocalizing to the plasma membrane under salinity
Dvorak, P.; Krasylenko, Y.; Ovecka, M.; Basheer, J.; Zapletalova, V.; Samaj, J.; Takac, T.
10.1101/2020.03.24.005363 — plant biology — Posted on 2020-03-25
903 Activity-dependent tuning of intrinsic excitability in mouse and human neurogliaform cells
Chittajallu, R.; Auville, K.; Mahadevan, V.; Lai, M.; Hunt, S.; Calvigioni, D.; Pelkey, K. A.; Zaghloul, K.; McBain, C. J.
10.1101/2020.03.24.004465 — neuroscience — Posted on 2020-03-25
904 Molecular Scale Spatio-Chemical Control of the Activating-Inhibitory Signal Integration in NK Cells
Toledo, E.; Le Saux, G.; Li, L.; Rosengenrg, M.; Keidar, Y.; Bhingradive, V.; Edri, A.; Hadad, U.; Di Primo, C.; Buffeteau, T.; Smith, A.-S.; Porgador, A.; Schvartzman, M.
10.1101/2020.03.24.004895 — immunology — Posted on 2020-03-25
907 The Genomic Formation of Human Populations in East Asia
Wang, C.-C.; Yeh, H.-Y.; Popov, A. N.; Zhang, H.-Q.; Matsumura, H.; Sirak, K.; Cheronet, O.; Kovalev, A.; Rohland, N.; Kim, A. M.; Bernardos, R.; Tumen, D.; Zhao, J.; Liu, Y.-C.; Liu, J.-Y.; Mah, M.; Mallick, S.; Wang, K.; Zhang, Z.; Adamski, N.; Broomandkhoshbacht, N.; Callan, K.; Culleton, B. J.; Eccles, L.; Lawson, A. M.; Michel, M.; Oppenheimer, J.; Stewardson, K.; Wen, S.; Yan, S.; Zalzala, F.; Chuang, R.; Huang, C.-J.; Shiung, C.-C.; Nikitin, Y. G.; Tabarev, A. V.; Tishkin, A. A.; Lin, S.; Sun, Z.-Y.; Wu, X.-M.; Yang, T.-L.; Hu, X.; Chen, L.; Du, H.; Bayarsaikhan, J.; Mijiddorj, E.; Erde
10.1101/2020.03.25.004606 — genomics — Posted on 2020-03-25
910 Neuron-glia Integrity: Functional Assessment, Molecular Underpinnings, and Implication for Higher Brain Functions
Zeng, H.; Zhang, X.; Wang, W.; Shen, Z.; Dai, Z.; Yu, Z.; Xu, S.; Yan, G.; Huang, Q.; Wu, R.; Chen, X.; Xu, H.
10.1101/2020.03.23.003681 — neuroscience — Posted on 2020-03-25
912 Brainstem development requires galactosylceramidase and is critical for the pathogenesis of Krabbe Disease
Weinstock, N. I.; Kreher, C.; Favret, J.; Bongarzone, E.; Wrabetz, L.; Feltri, M. L.; Shin, D.
10.1101/2020.03.25.007542 — neuroscience — Posted on 2020-03-25
917 The bacterial community structure dynamics in Meloidogyne incognita infected roots and its role in worm-microbiome interactions
Yergaliyev, T.; Alexander-Shani, R.; Dimeretz, H.; Pivonia, S.; Bird, D. M.; Rachmilevitch, S.; Szitenberg, A.
10.1101/2020.03.25.007294 — microbiology — Posted on 2020-03-25
919 Serotonergic drugs inhibit CHIKV infection at different stages of the cell entry pathway
Bouma, E. M.; van de Pol, D. P. I.; Sanders, I. D.; Rodenhuis-Zybert, I. A.; Smit, J. M.
10.1101/2020.03.24.005066 — microbiology — Posted on 2020-03-25
920 Revisiting giraffe photo-identification using deep learning and network analysis
Miele, V.; Dussert, G.; Spataro, B.; Chamaille-Jammes, S.; Allaine, D.; Bonenfant, C.
10.1101/2020.03.25.007377 — ecology — Posted on 2020-03-25
921 FEP-based screening prompts drug repositioning against COVID-19
Li, Z.; Li, X.; Huang, Y.-Y.; Wu, Y.; Zhou, L.; Liu, R.; Wu, D.; Zhang, L.; Liu, H.; Xu, X.; Zhang, Y.; Cui, J.; Wang, X.; Luo, H.-B.
10.1101/2020.03.23.004580 — biophysics — Posted on 2020-03-25
922 Current estimates of malaria basic reproduction number underestimate parasite transmission efficiency due to multiple blood feeding
Shaw, W. R.; Holmdahl, I. E.; Itoe, M. A.; Werling, K.; Marquette, M.; Paton, D. G.; Singh, N.; Buckee, C. O.; Childs, L. M.; Catteruccia, F.
10.1101/2020.03.24.991356 — microbiology — Posted on 2020-03-25
928 Machine learning pattern recognition and differential network analysis of gastric microbiome in the presence of proton pump inhibitor treatment or Helicobacter pylori infection
Ciucci, S.; Duran, C.; Palladini, A.; Ijaz, U. Z.; Sterbini, F. P.; Masucci, L.; Cammarota, G.; Ianiro, G.; Spuul, P.; Schroeder, M.; Grill, S. W.; Parsons, B. N.; Pritchard, M.; Posteraro, B.; Sanguinetti, M.; Gasbarrini, G.; Gasbarrini, A.; Cannistraci, C. V.
10.1101/2020.03.24.005587 — systems biology — Posted on 2020-03-25
929 The role of islet lipid composition remodeling in regulation of beta-cell death via ADP-ribosyl-acceptor glycohydrolase ARH3 signaling in insulitis
Nakayasu, E. S.; Guney, M.; Kyle, J.; Sarbaugh, D.; Deiter, C.; Yin, R.; Cui, Y.; Nicora, C.; Syed, F.; Juan-Mateu, J.; Mirmira, R. G.; Evans-Molina, C.; Eizirik, D. L.; Webb-Robertson, B.-J.; Burnum-Johnson, K.; Orr, G.; Laskin, J.; Metz, T. O.; Sussel, L.; Ansong, C.
10.1101/2020.03.23.004481 — systems biology — Posted on 2020-03-25
931 Variable expression quantitative trait loci analysis of breast cancer risk variants
Wiggins, G. A.; Black, M. A.; Dunbier, A.; Merriman, T.; Pearson, J.; Walker, L. C.
10.1101/2020.03.23.004366 — cancer biology — Posted on 2020-03-25
934 SerraNA: a program to infer elastic constants from local to global using nucleic acids simulation data
Velasco-Berrelleza, V.; Burman, M.; Shepherd, J. W.; Leake, M. C.; Golestanian, R.; Noy, A.
10.1101/2020.03.24.004945 — biophysics — Posted on 2020-03-25
935 AntiCP 2.0: An updated model for predicting anticancer peptides
Agrawal, P.; Bhagat, D.; Mahalwal, M.; Sharma, N.; Raghava, G. P. S.
10.1101/2020.03.23.003780 — bioinformatics — Posted on 2020-03-25
937 Structural insights into assembly and function of the RSC chromatin remodeling complex
Leschziner, A. E.; Baker, R. W.; Reimer, J. M.; Dominguez, R.; Carman, P. J.; Arakawa, T.
10.1101/2020.03.24.006361 — molecular biology — Posted on 2020-03-25
938 A full cycle anti-viral drug screen identifies a clinical compound against adenovirus infection
Georgi, F.; Kuttler, F.; Murer, L.; Andriasyan, V.; Witte, R.; Yakimovich, A.; Turcatti, G.; Greber, U. F.
10.1101/2020.03.24.006346 — microbiology — Posted on 2020-03-25
939 The Enterprise: A massive transposon carrying Spok meiotic drive genes
Vogan, A. A.; Ament-Velasquez, S. L.; Bastiaans, E.; Wallerman, O.; Saupe, S. J.; Suh, A.; Johannesson, H.
10.1101/2020.03.25.007153 — genomics — Posted on 2020-03-25
941 No room to roam: King Cobras reduce movement in agriculture
Marshall, B. M.; Crane, M.; Silva, I.; Strine, C. T.; Jones, M. D.; Hodges, C. W.; Suwanwaree, P.; Artchawakom, T.; Waengsothorn, S.; Goode, M.
10.1101/2020.03.24.006676 — ecology — Posted on 2020-03-25
942 m6A RNA methylation regulates the fate of endogenous retroviruses
Chelmicki, T.; Roger, E.; Teissandier, A.; Rucli, S.; Dossin, F.; Dura, M.; Fouassier, C.; Lameiras, S.; Bourc'his, D.
10.1101/2020.03.24.005488 — cell biology — Posted on 2020-03-25
946 The functional landscape of patient derived RNF43 mutations predicts Wnt inhibitor sensitivity
Yu, J.; Bt Mohamed Yuso, P. A.; Goh, P.; HARMSTON, N. P.; Epstein, D.; Virshup, D. M.; Madan, B.
10.1101/2020.03.25.006999 — cancer biology — Posted on 2020-03-25
947 Accelerating Maximal-Exact-Match Seeding with Enumerated Radix Trees
Subramaniyan, A.; Wadden, J.; Goliya, K.; Ozog, N.; Wu, X.; Narayanasamy, S.; Blaauw, D.; Das, R.
10.1101/2020.03.23.003897 — bioinformatics — Posted on 2020-03-25
948 miRSwitch: Detecting microRNA arm shift and switch events
Kern, F. M.; Amand, J.; Senatorov, I.; Isakova, A.; Backes, C.; Meese, E.; Keller, A.; Fehlmann, T.
10.1101/2020.03.25.007351 — bioinformatics — Posted on 2020-03-25
949 Role of endothelial microRNA-150 in pulmonary arterial hypertension
Russomanno, G.; Jo, K. B.; Abdul-Salam, V. B.; Morgan, C.; Alzaydi, M.; Wilkins, M. R.; Wojciak-Stothard, B.
10.1101/2020.03.25.007021 — physiology — Posted on 2020-03-25
950 Whole Genome De Novo Variant Identification with FreeBayes and Neural Network Approaches
Richter, F.; Morton, S.; Qi, H.; Kitaygorodksy, A.; Wang, J.; Homsy, J.; DePalma, S.; Patel, N.; Gelb, B. D.; Seidman, J. G.; Seidman, C. E.; Shen, Y.
10.1101/2020.03.24.994160 — genomics — Posted on 2020-03-25
952 Fibrinolytic niche is requested for alveolar type 2 cell-mediated alveologenesis and injury repair
Ali, G.; Zhao, R.; Zhang, M.; Jain, K. G.; Chang, J.; Komatsu, S.; Fang, X.; Zhou, B.; Liang, J.; Jiang, D.; Ikebe, M.; Matthay, M. A.; Ji, H.-L.
10.1101/2020.03.24.006270 — cell biology — Posted on 2020-03-25
953 Ab-Ligity: Identifying sequence-dissimilar antibodies that bind to the same epitope
Wong, W. K.; Robinson, S. A.; Bujotzek, A.; Georges, G.; Lewis, A. P.; Shi, J.; Snowden, J.; Taddese, B.; Deane, C.
10.1101/2020.03.24.004051 — bioinformatics — Posted on 2020-03-25
954 Towards CNN Representations for Small Mass Spectrometry Data Classification: From Transfer Learning to Cumulative Learning
Seddiki, K.; Saudemont, P.; Precioso, F.; Ogrinc, N.; Wisztorski, M.; Salzet, M.; Fournier, I.; Droit, A.
10.1101/2020.03.24.005975 — bioinformatics — Posted on 2020-03-25
957 Alternative splicing switches STIM1 targeting to specialized membrane contact sites and modifies SOCE
Knapp, M. L.; Förderer, K.; Alansary, D.; Jung, M.; Schwarz, Y.; Lis, A.; Niemeyer, B. A.
10.1101/2020.03.25.005199 — molecular biology — Posted on 2020-03-25
959 Common maternal and fetal genetic variants show expected polygenic effects on the probability of being born small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies
Beaumont, R. N.; Kotecha, S. J.; Wood, A. R.; Knight, B. A.; Sebert, S.; McCarthy, M. I.; Hattersley, A. T.; Jarvelin, M.-R.; Timpson, N. J.; Freathy, R. M.; Kotecha, S.
10.1101/2020.03.25.005660 — genetics — Posted on 2020-03-25
960 Wavelet Screening: a novel approach to analysing GWAS data
Denault, W. R. P.; Gjessing, H. K.; Juodakis, J.; Jacobsson, B.; Jugessur, A.
10.1101/2020.03.24.006163 — bioinformatics — Posted on 2020-03-25
963 Structure and mechanism of potent bifunctional β-lactam- and homoserine lactone-degrading enzymes from marine microorganisms
Selleck, C.; Monteiro Pedroso, M.; Wilson, L.; Krco, S.; Knaven, E. G.; Miraula, M.; Mitic, N.; Larrabee, J.; Bruck, T.; Clark, A.; Guddat, L.; Schenk, G.
10.1101/2020.03.24.006742 — biochemistry — Posted on 2020-03-25
964 Potent human neutralizing antibodies elicited by SARS-CoV-2 infection
Ju, B.; Zhang, Q.; Ge, X.; Wang, R.; Yu, J.; Shan, S.; Zhou, B.; Song, S.; Tang, X.; Yu, J.; Ge, J.; Lan, J.; Yuan, J.; Wang, H.; Zhao, J.; Zhang, S.; Wang, Y.; Shi, X.; Liu, L.; Wang, X.; Zhang, Z.; Zhang, L.
10.1101/2020.03.21.990770 — immunology — Posted on 2020-03-25
968 The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis
Carrat, G. R.; Haythorne, E.; Tomas, A.; Haataja, L.; Andreas, M.; Arvan, P.; Piunti, A.; Cheng, K.; Huang, M.; Pullen, T.; Georgiadou, E.; Stylianides, T.; Amirruddin, N. S.; Salem, V.; Distaso, W.; Cakebread, A.; Heesom, K. J.; Lewis, P. A.; Hodson, D.; Briant, L. J.; Fung, A. C. H.; Sessions, R. B.; Alpy, F.; Kong, A. P. S.; Benke, P. I.; Torta, F.; Teo, A. K. K.; Leclerc, I.; Solimena, M.; Wigley, D. B.; Rutter, G. A.
10.1101/2020.03.25.007286 — cell biology — Posted on 2020-03-25
969 COVID-19 Vaccine Candidates: Prediction and Validation of 174 SARS-CoV-2 Epitopes
Prachar, M.; Justesen, S.; Steen-Jensen, D. B.; Thorgrimsen, S. P.; Jurgons, E.; Winther, O.; Bagger, F. O.
10.1101/2020.03.20.000794 — immunology — Posted on 2020-03-25
971 Enhancing the Antiviral Efficacy of RNA-Dependent RNA Polymerase Inhibition by Combination with Modulators of Pyrimidine Metabolism
Liu, Q.; Gupta, A.; Okesli-Armlovich, A.; Qiao, W.; Fischer, C.; Smith, M.; Carette, J. E.; Bassik, M. C.; Khosla, C.
10.1101/2020.03.24.992230 — biochemistry — Posted on 2020-03-25
973 Regenerated Interneurons Integrate Into Locomotor Circuitry Following Spinal Cord Injury
Vasudevan, D.; Liu, Y.-C.; Barrios, J. P.; Wheeler, M. K.; Douglass, A. D.; Dorsky, R. I.
10.1101/2020.03.23.003806 — neuroscience — Posted on 2020-03-25
975 Integrated analysis of a compendium of RNA-Seq datasets for splicing factors
Yu, P.; Li, J.; Deng, S.-P.; Zhang, F.; Grozdanov, P. N.; Chin, E. W. M.; Martin, S. D.; Vergnes, L.; Islam, M. S.; Sun, D.; LaSalle, J. M.; McGee, S. L.; Goh, E.; MacDonald, C. C.; Jin, P.
10.1101/2020.03.24.006791 — bioinformatics — Posted on 2020-03-25
976 Human microglia upregulate cytokine signatures and accelerate maturation of neural networks
Schmunk, G.; Chang, K. N.; Soliman, S. S.; Keefe, M. G.; Bogdanoff, D.; Tejera, D.; Ziffra, R. S.; Shin, D.; Allen, D. E.; Chhun, B. B.; McGinnis, C. S.; Winkler, E. A.; Abla, A. A.; Chang, E. F.; Gartner, Z. J.; Mehta, S. B.; Piao, X.; Hengen, K. B.; Nowakowski, T. J.
10.1101/2020.03.24.006874 — developmental biology — Posted on 2020-03-25
977 FcRn, but not FcgRs, drives maternal-fetal transplacental transport of human IgGantibodies
Borghi, S.; Bournazos, S.; Thulin, N.; Li, C.; Gajewski, A.; Sherwood, R.; Zhang, S.; Harris, E.; Jagannathan, P.; Wang, L.-X.; Ravetch, J. V.; Wang, T. T.
10.1101/2020.03.22.999243 — immunology — Posted on 2020-03-25
978 Occurrence cubes: a new paradigm for aggregating species occurrence data
Oldoni, D.; Groom, Q.; Adriaens, T.; Davis, A. J. S.; Reyserhove, L.; Strubbe, D.; Vanderhoeven, S.; Desmet, P.
10.1101/2020.03.23.983601 — ecology — Posted on 2020-03-25
979 BatchServer: a web server for batch effect evaluation, visualization and correction
Zhu, T.; Chen, G.-B.; Yuan, C.; Sun, R.; Zhang, F.; Yi, X.; Zhou, S.; Guo, T.
10.1101/2020.03.23.996264 — bioinformatics — Posted on 2020-03-25
980 Evaluation of biodiversity in estuaries using environmental DNA metabarcoding
Ahn, H.; Kume, M.; Terashima, Y.; Ye, F.; Kameyama, S.; Miya, M.; Yamashita, Y.; Kasai, A.
10.1101/2020.03.22.997809 — ecology — Posted on 2020-03-25
981 Screening for functional circular RNAs using the CRISPR-Cas13 system
Li, S.; Li, X.; Xue, W.; Zhang, L.; Cao, S.-M.; Lei, Y.-N.; Yang, L.-Z.; Cao, S.-K.; Zhang, J.-L.; Gao, X.; Wei, J.; Li, J.; Yang, L.; Chen, L.-L.
10.1101/2020.03.23.002865 — molecular biology — Posted on 2020-03-25
982 Practical and effective diagnosis of animal anthrax in endemic low-resource settings
Aminu, O. R.; Lembo, T.; Zadoks, R. N.; Biek, R.; Lewis, S.; Kiwelu, I.; Mmbaga, B. T.; Mshanga, D.; Shirima, G.; Denwood, M.; Forde, T.
10.1101/2020.03.24.004382 — microbiology — Posted on 2020-03-25
983 Direct evidence of abortive lytic infection-mediated establishment of Epstein-Barr virus latency during B-cell infection
Inagaki, T.; Sato, Y.; Ito, J.; Takaki, M.; Okuno, Y.; Yaguchi, M.; Masud, H. M. A. A.; Watanabe, T.; Sato, K.; Iwami, S.; Murata, T.; Kimura, H.
10.1101/2020.03.23.004440 — microbiology — Posted on 2020-03-25
988 Full-length genome sequence of segmented RNA virus from ticks was obtained using small RNA sequencing data
Xu, X.; Bei, J.; Xuan, Y.; Chen, J.; Chen, D.; Barker, S. C.; Kelava, S.; He, B.; shan, g.; chen, z.
10.1101/2020.03.24.004796 — bioinformatics — Posted on 2020-03-25
990 WOX9 functions antagonistic to STF and LAM1 to regulate leaf blade expansion in Medicago truncatula and Nicotiana sylvestris
Wolabu, T. W.; Wang, H.; Tadesse, D. T.; Zhang, F.; Behzadirad, M.; Tvorogova, V. E.; Abdelmageed, H.; Liu, Y.; Chen, N.; Jianghua, C.; Allen, R. D.; Tadege, M.
10.1101/2020.03.23.003715 — plant biology — Posted on 2020-03-25
992 Chikungunya virus requires an intact microtubule network for efficient viral genome delivery
Hoornweg, T. E.; Bouma, E. M.; van de Pol, D. P. I.; Rodenhuis-Zybert, I. A.; Smit, J. M.
10.1101/2020.03.24.004820 — microbiology — Posted on 2020-03-25
994 HELLO: A hybrid variant calling approach
Ramachandran, A.; Lumetta, S. S.; Klee, E.; Chen, D.
10.1101/2020.03.23.004473 — bioinformatics — Posted on 2020-03-25
998 Improved segmentation of the intracranial and ventricular volumes in populations with cerebrovascular lesions and atrophy using 3D CNNs
Ntiri, E. E.; Holmes, M. F.; Mojiri, P.; Ramirez, J.; Gao, F.; Ozzoude, M.; Adamo, S.; Scott, C.; Dowlatshahi, D.; Lawrence-Dewar, J. M.; Kwan, D.; Lang, A. E.; Symons, S.; Bartha, R.; Strother, S.; Tardif, J.-C.; Masellis, M.; Swartz, R. H.; Moody, A.; Black, S.; Goubran, M.
10.1101/2020.03.23.000844 — neuroscience — Posted on 2020-03-25
1003 Characterization of amyloid β fibril formation under microgravity conditions
Yagi-Utsumi, M.; Yanaka, S.; Song, C.; Satoh, T.; Yamazaki, C.; Kasahara, H.; Shimazu, T.; Murata, K.; Kato, K.
10.1101/2020.03.23.004341 — biophysics — Posted on 2020-03-25
1004 Monodisperse drops templated by 3D-structured microparticles
Wu, C.-Y.; Wang, B.; de Rutte, J.; Ouyang, M.; Joo, A.; Jacobs, M.; Ha, K.; Bertozzi, A.; Di Carlo, D.
10.1101/2020.03.22.001065 — bioengineering — Posted on 2020-03-25
1005 Decoupling gene knockout effects from gene functions by evolutionary analyses
Liu, L.; Liu, M.; Zhang, D.; Deng, S.; Chen, P.; Yang, J.; Xie, Y.; He, X.
10.1101/688358 — genetics — Posted on 2020-03-25
1006 Elucidating another level of epigenetic regulation in osteoarthritis by identifying functional cis-acting long non-coding RNAs and their targets in articular cartilage
van Hoolwerff, M.; Metselaar, P. P. I.; Tuerlings, M.; Suchiman, E. H. E. D.; Lakenberg, N.; Ramos, Y. Y. F. M.; Cats, D.; Nelissen, R. R. G. H. H.; Broekhuis, D.; Mei, H.; Coutinho de Almeida, R.; Meulenbelt, I.
10.1101/2020.03.23.003020 — genomics — Posted on 2020-03-25
1010 Atypical brain asymmetry in autism - a candidate for clinically meaningful stratification
Floris, D. L.; Wolfer, T.; Zabihi, M.; Holz, N. E.; Zwiers, M. P.; Charman, T.; Tillmann, J.; Ecker, C.; Dell'Acqua, F.; Banaschewski, T.; Moessnang, C.; Baron-Cohen, S.; Holt, R.; Durston, S.; Loth, E.; Murphy, D. G. M.; Marquand, A.; Buitelaar, J. K.; Beckmann, C. F.
10.1101/2020.03.24.000349 — neuroscience — Posted on 2020-03-25
1011 Delineating the relationship between immune system aging and myogenesis in muscle repair
Tobin, S. W.; Alibhai, F. J.; Wlodarek, L.; Yeganeh, A.; Millar, S.; Wu, J.; Li, S.; Weisel, R. D.; Li, R.-K.
10.1101/2020.03.23.003160 — immunology — Posted on 2020-03-25
1013 Genome-wide locus sequence typing (GLST) of eukaryotic pathogens
Schwabl, P.; Maiguashca Sanchez, J.; Costales, J. A.; Ocana, S.; Segovia, M.; Carrasco, H. J.; Hernandez, C.; Ramírez, J. D.; Lewis, M. D.; Grijalva, M. J.; Llewellyn, M. S.
10.1101/2020.03.24.003590 — genetics — Posted on 2020-03-25
1015 Cellular senescence limits acute lung injury induced by mechanical ventilation
Blazquez-Prieto, J.; Huidobro, C.; Lopez-Alonso, I.; Amado-Rodriguez, L.; Martin-Vicente, P.; Lopez-Martinez, C.; Crespo, I.; Pantoja, C.; Fernandez-Marcos, P. J.; Serrano, M.; Sznajder, J. I.; Albaiceta, G. M.
10.1101/2020.03.24.005983 — cell biology — Posted on 2020-03-25
1017 Reaching to sounds in virtual reality: A multisensory-motor approach to re-learn sound localisation
Valzolgher, C.; Verdelet, G.; Salemme, R.; Lombardi, L.; Gaveau, V.; Farne, A.; Pavani, F.
10.1101/2020.03.23.003533 — neuroscience — Posted on 2020-03-25
1020 Knowledge-based classification of fine-grained immune cell types in single-cell RNA-Seq data with ImmClassifier
Liu, X.; Gosline, S. J.; Pflieger, L. T.; Wallet, P.; Iyer, A.; Guinney, J. J.; Bild, A.; Chang, J. T.
10.1101/2020.03.23.002758 — bioinformatics — Posted on 2020-03-25
1024 Recapitulating evolutionary divergence in a single regulatory element causes expression changes of the lens gene Tdrd7
Roscito, J. G.; Subramanian, K.; Naumann, R.; Sarov, M.; Shevchenko, A.; Bogdanova, A.; Kurth, T.; Forster, L.; Kreysing, M.; Hiller, M.
10.1101/2020.03.22.002535 — evolutionary biology — Posted on 2020-03-25
1026 Endosomal free fatty acid receptor 2 signaling is essential for propionate-induced anorectic gut hormone release
Caengprasath, N.; Gonzalez-Abuin, N.; Shchepinova, M.; Ma, Y.; Inoue, A.; Tate, E. W.; Frost, G.; Hanyaloglu, A.
10.1101/2020.03.24.004762 — cell biology — Posted on 2020-03-25
1033 Cooperative molecular networks drive a mammalian cell state transition
Lackner, A.; Sehlke, R.; Garmhausen, M.; Stirparo, G. G.; Huth, M.; Titz-Teixeira, F.; van der Lelij, P.; Ramesmayer, J.; Thomas, H. F.; Ralser, M.; Santini, L.; Sarov, M.; Stewart, A. F.; Smith, A. G.; Beyer, A.; Leeb, M.
10.1101/2020.03.23.000109 — systems biology — Posted on 2020-03-25
1035 Does gravity shape internal representations of space for human 3D perception?
Morfoisse, T.; Herrera Altamira, G.; Angelini, L.; Clement, G.; Beraneck, M.; McIntyre, J.; Tagliabue, M.
10.1101/2020.03.23.003061 — neuroscience — Posted on 2020-03-25
1036 Mechanism of action of HBV capsid assembly modulators predicted from binding to early assembly intermediates
Pavlova, A.; Bassit, L.; Cox, B.; Korablyov, M.; Chipot, C.; Verma, K.; Russell, O. O.; Schinazi, R. F.; Gumbart, J. C.
10.1101/2020.03.23.002527 — molecular biology — Posted on 2020-03-25
1037 Sex determination through X-Y heterogamety in Salix nigra
Sanderson, B. J.; Feng, G.; Hu, N.; Grady, J.; Carlson, C. H.; Smart, L. B.; Keefover-Ring, K.; Yin, T.; Ma, T.; Liu, J.; DiFazio, S.; Olson, M. S.
10.1101/2020.03.23.000919 — genomics — Posted on 2020-03-25
1040 Paternal exposure to DDT programs breast cancer development in daughters via sperm miRNA in a mouse model
da Cruz, R. S.; Cao, H.; Fontelles, C. C.; Nasir, A.; Krebs, A.; Cruz, M. I.; Jin, L.; de Assis, S.
10.1101/2020.03.23.004135 — cancer biology — Posted on 2020-03-25
1042 Ultra-Low-Cost Integrated Silicon-based Transducer for On-Site, Genetic Detection of Pathogens
Nunez-Bajo, E.; Kasimatis, M.; Cotur, Y.; Asfour, T.; Collins, A.; Tanriverdi, U.; Grell, M.; Kaisti, M.; Senesi, G.; Stevenson, K.; Guder, F.
10.1101/2020.03.23.002931 — bioengineering — Posted on 2020-03-25
1043 Channel Embedding for Informative Protein Identification from Highly Multiplexed Images
Magid, S. A.; Jang, W.-D.; Schapiro, D.; Wei, D.; Tompkin, J.; Sorger, P. K.; Pfister, H.
10.1101/2020.03.24.004085 — pathology — Posted on 2020-03-25
1044 Genetic and behavioral adaptation of Candida parapsilosis to the microbiome of hospitalized infants revealed by in situ genomics, transcriptomics and proteomics
West, P. T.; Peters, S. L.; Olm, M. R.; Yu, F. B.; Lou, Y. C.; Firek, B. A.; Baker, R.; Johnson, A. D.; Morowitz, M. J.; Hettich, R. L.; Banfield, J. F.
10.1101/2020.03.23.004093 — microbiology — Posted on 2020-03-25
1045 Genomic basis of parallel adaptation varies with divergence in Arabidopsis and its relatives
Bohutinska, M.; Vlcek, J.; Yair, S.; Leanen, B.; Konecna, V.; Fracassetti, M.; Slotte, T.; Kolar, F.
10.1101/2020.03.24.005397 — evolutionary biology — Posted on 2020-03-25
1049 Click-chemistry enabled directed evolution of glycosynthases for bespoke glycans synthesis
Agrawal, A.; Bandi, C. K.; Burgin, T.; Woo, Y.; Mayes, H. B.; Chundawat, S. P. S.
10.1101/2020.03.23.001982 — biochemistry — Posted on 2020-03-25
1050 Genetically Encoded, Multivalent Liquid Glycan Array (LiGA)
Sojitra, M.; Sarkar, S.; Maghera, J.; Rodrigues, E.; Carpenter, E. J.; Seth, S.; Vinals, D. F.; Bennett, N. J.; Reddy, R.; Khalil, A.; Xue, X.; Bell, M.; Zheng, R. B.; Zhang, P.; Ling, C. C.; Lowary, T. L.; Paulson, J. C.; Macauley, M. S.; Derda, R.
10.1101/2020.03.24.997536 — biochemistry — Posted on 2020-03-25
1051 Monoclonal antibody stability can be usefully monitored using the excitation-energy-dependent fluorescence edge-shift
Knight, M.; Woolley, R.; Kwok, A.; Parsons, S.; Jones, H.; Gulacsy, C.; Phaal, P.; Kassaar, O.; Dawkins, K.; Rodriguez, E.; Marques, A.; Bowsher, L.; Wells, S. A.; Watts, A.; van den Elsen, J. M.; Turner, A.; Ohara, J.; Pudney, C. R.
10.1101/2020.03.23.003608 — biochemistry — Posted on 2020-03-25
1052 Grain number and genotype drive nitrogen-dependent yield response in the C4 model Setaria italica (L.) P. Beauv.
Bandyopadhyay, T.; Swarbreck, S. M.; Jaiswal, V.; Gupta, R.; Bentley, A. R.; Griffiths, H.; Prasad, M.
10.1101/2020.03.23.003004 — plant biology — Posted on 2020-03-25
1054 Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging
Li, H.; Yang, J.; tian, C.; Diao, M.; Wang, Q.; Zhao, S.; Li, S.; Tan, F.; Tian, H.; Lin, Z.; Alexander Deska Gauthier, D.; Thompson, G.; Zhang, Y.; Wang, T.; Shui, W.; Liu, Z.; Zhong, G.
10.1101/2020.03.22.002642 — neuroscience — Posted on 2020-03-25
1056 Host-derived lipids from tuberculous pleurisy impair macrophage microbicidal-associated metabolic activity
Marin Franco, J. L.; Genoula, M.; Corral, D.; Duette, G.; Ferreyra, M.; Maio, M.; Dolotowicz, B.; Aparicio-Trejo, O. E.; Patino-Martinez, E.; Fuentes, F.; Soldan, V.; Morana, E. J.; Palmero, D.; Ostrowski, M.; Schierloh, P.; Sanchez-Torres, C.; Hernandez-Pando, R.; Pedraza-Chaverri, J.; Romboust, Y.; Layre, E.; Hudrisier, D.; Verollet, C.; Neyrolles, O.; Sasiain, M. d. C.; Lugo-Villarino, G.; Balboa, L.
10.1101/2020.03.23.001818 — immunology — Posted on 2020-03-25
1061 Three Essential Resources to Improve Differential Scanning Fluorimetry (DSF) Experiments
Wu, T.; Yu, J.; Gale-Day, Z.; Woo, A.; Suresh, A.; Hornsby, M.; Gestwicki, J. E.
10.1101/2020.03.22.002543 — biochemistry — Posted on 2020-03-25
1063 Transcriptome-Wide Combinatorial RNA Structure Probing in Living Cells
Spitale, R.; Chan, D.; Feng, C.; England, W.; Wyman, D.; Flynn, R.; Wang, X.; Shi, Y.; Mortazavi, A.
10.1101/2020.03.24.006866 — biochemistry — Posted on 2020-03-25
1065 High-Throughput 5' UTR Engineering for Enhanced Protein Production in Non-Viral Gene Therapies
Cao, J.; Maria Novoa, E.; Zhang, Z.; Chen, W. C.; Liu, D.; Choi, G. C.; Wong, A. S.; Wehrspaun, C.; Kellis, M.; Lu, T. K.
10.1101/2020.03.24.006486 — synthetic biology — Posted on 2020-03-25
1068 Integrative Epigenomic and Transcriptomic Analysis Reveals Robust Metabolic Switching in the Brain During Intermittent Fasting
Ng, G. Y.-Q.; Sheng, D. P. L. K.; Kang, S.-W.; Fann, D. Y.-W.; Kim, J.; Alli-Shaik, A.; Cho, Y.-S.; Han, J.; Sul, J.-H.; Karamyan, V.; Okun, E.; Dheen, T.; Hande, M. P.; Vemuganti, R.; Mallilankaraman, K.; Kennedy, B. K.; Drummond, G. R.; Sobey, C. G.; Gunaratne, J.; Mattson, M. P.; Foo, R. S.-Y.; Jo, D.-G.; Arumugam, T.
10.1101/2020.03.22.002725 — neuroscience — Posted on 2020-03-25
1069 mir-21 is associated with inactive low molecular weight Argonaute complexes in thyroid cancer cell lines
Powell, B. H.; Turchinovich, A.; Wang, Y.; Liao, Z.; Aasif Dar, M.; La Rocca, G.; Umanah, G. E.; Zeiger, M. A.; Umbricht, C. B.; Witwer, K. W.
10.1101/2020.03.24.006072 — molecular biology — Posted on 2020-03-25
1073 Genetic analysis identifies the Ostrea stentina/aupouria/equestris oyster species complex in Hawai'i, and resolves its lineage as the western Pacific O. equestris
Sutton, J. T.; Nishimoto, J.; Schrader, J.; Agonias, K.; Antonio, N.; Bautista, B.; Cabarloc, R.; Fakasieiki, M.; Gonong, N. A. M.; Ramangmou, T.; Uehara, L.; Wong, J.; Wilkie, D.; Littrell, D.; Rem-McGeachy, M.; Chandler-Iao, R.; Haws, M.
10.1101/2020.03.22.002444 — genetics — Posted on 2020-03-25
1075 Loss of Hem1 disrupts macrophage function and impacts on migration, phagocytosis and integrin-mediated adhesion
Stahnke, S.; Döring, H.; Kusch, C.; de Gorter, D. J. J.; Dütting, S.; Guledani, A.; Pleines, I.; Schnoor, M.; Sixt, M.; Geffers, R.; Rohde, M.; Müsken, M.; Kage, F.; Steffen, A.; Faix, J.; Nieswandt, B.; Rottner, K.; Stradal, T. E. B.
10.1101/2020.03.24.005835 — cell biology — Posted on 2020-03-25
1081 Glycoengineering of NK cells with glycan ligands of CD22 and selectins for B-cell lymphoma therapy
Hong, S.; Yu, C.; Wang, P.; Shi, Y.; Cheng, B.; CHEN, M.; Chapla, D. G.; Reigh, N.; Narimatsu, Y.; Chen, X.; Clausen, H.; Moremen, K. W.; Macauley, M. S.; Paulson, J. C.; Wu, P.
10.1101/2020.03.23.004325 — bioengineering — Posted on 2020-03-25
1083 A unifying structural and functional model of the coronavirus replication organelle: tracking down RNA synthesis
Snijder, E. J.; Limpens, R. W. A. L.; de Wilde, A. H.; de Jong, A. W. M.; Zevenhoven-Dobbe, J. C.; Maier, H. J.; Faas, F. G. A.; Koster, A. J.; Barcena, M.
10.1101/2020.03.24.005298 — microbiology — Posted on 2020-03-24
1091 Unilateral vocal nerve resection alters neurogenesis in the avian song system in a region-specific manner
Aronowitz, J. V.; Perez, A.; O'Brien, C.; Aziz, S.; Rodriguez, E.; Wasner, K.; Ribeiro, S.; Green, D.; Faruk, F.; Pytte, C.
10.1101/2020.03.24.005330 — neuroscience — Posted on 2020-03-24
1094 Cellular heterogeneity of the LH receptor and its significance for cyclic GMP signaling in mouse preovulatory follicles
Baena, V.; Owen, C. M.; Uliasz, T. F.; Lowther, K. M.; Yee, S.-P.; Terasaki, M.; Egbert, J.; Jaffe, L. A.
10.1101/2020.02.06.937995 — cell biology — Posted on 2020-03-24
1095 Spontaneous Cell Fusions as a Mechanism of Parasexual Recombination in Tumor Cell Populations
Miroshnychenko, D.; Baratchart, E.; Ferrall-Fairbanks, M.; Vander Velde, R.; Laurie, M. A.; Bui, M.; Altrock, P. M.; Basanta, D.; Marusyk, A.
10.1101/2020.03.09.984419 — cancer biology — Posted on 2020-03-24
1097 Enhanced donor heart preservation by therapeutic inhibition of acid sensing ion channel 1a
Redd, M.; Scheuer, S.; Saez, N.; Gao, L.; Hicks, M.; Villanueva, J.; Reichelt, M.; Peart, J.; See Hoe, L.; Chiu, H.; Chen, X.; Sun, Y.; Suen, J.; Hatch, R.; Rollo, B.; Alzubaidi, M.; Maljevic, S.; Qaiffe-Ryan, G. A.; Thomas, W.; Hudson, J. E.; Porrello, E.; Cuellar-Partida, G.; Fraser, J.; Petrou, S.; King, G.; MacDonald, P.; Palpant, N.
10.1101/869826 — physiology — Posted on 2020-03-24
1098 WDR90 is a centriolar microtubule wall protein important for centriole architecture integrity.
Steib, E.; Gambarotto, D.; Laporte, M. H.; Olieric, N.; Zheng, C.; Borgers, S.; Olieric, V.; Le Guennec, M.; Koll, F.; Tassin, A.-M.; Steinmetz, M. O.; Guichard, P.; Hamel, V.
10.1101/2020.02.15.950444 — cell biology — Posted on 2020-03-24
1102 The Latent Genetic Structure of Impulsivity and its Relation to Internalizing Psychopathology
Gustavson, D. E.; Friedman, N. P.; Fontanillas, P.; Elson, S. L.; 23andMe Research Team, ; Palmer, A. A.; Sanchez-Roige, S.
10.1101/2020.01.07.897231 — genetics — Posted on 2020-03-24
1106 Opponent regulation of action performance and timing by striatonigral and striatopallidal pathways
Bakhurin, K. I.; Li, X.; Friedman, A. D.; Lusk, N. A.; Watson, G. D.; Kim, N.; Yin, H. H.
10.1101/2019.12.26.889030 — neuroscience — Posted on 2020-03-24
1107 TMEM184B promotes pruriceptive neuron specification to facilitate itch sensitivity
Larsen, E. G.; Cho, T. S.; McBride, M. L.; Feng, J.; Manivannan, B.; Madura, C.; Klein, N. E.; Wright, E. B.; Garcia-Verdugo, H. D.; Jarvis, C.; Khanna, R.; Hu, H.; Largent-Milnes, T. M.; Bhattacharya, M. R. C.
10.1101/2020.01.25.919902 — neuroscience — Posted on 2020-03-24
1108 Atypical chemoreceptor arrays accommodate high membrane curvature
Muok, A. R.; Ortega, D. R.; Kurniyati, K.; Yang, W.; Sidi Mabrouk, A.; Li, C.; Crane, B. R.; Briegel, A.
10.1101/2020.03.11.986844 — microbiology — Posted on 2020-03-24
1109 AtacWorks: A deep convolutional neural network toolkit for epigenomics
Lal, A.; Chiang, Z. D.; Yakovenko, N.; Duarte, F. M.; Israeli, J.; Buenrostro, J. D.
10.1101/829481 — genomics — Posted on 2020-03-24
1110 In Silico Modeling of Metabolic State in Single Th17 Cells Reveals Novel Regulators of Inflammation and Autoimmunity
Wagner, A.; Wang, C.; DeTomaso, D.; Avila-Pacheco, J.; Zaghouani, S.; Fessler, J.; Eyzaguirre, S.; Akama-Garren, E.; Pierce, K.; Ron-Harel, N.; Douglas, V. P.; Haigis, M.; Sobel, R. A.; Clish, C.; Regev, A.; Kuchroo, V. K.; Yosef, N.
10.1101/2020.01.23.912717 — genomics — Posted on 2020-03-24
1114 A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress
Stephani, M.; Picchianti, L.; Gajic, A.; Beveridge, R.; Skarwan, E.; Sanchez de Medina Hernandez, V.; Mohseni, A.; Clavel, M.; Zeng, Y.; Naumann, C.; Matuszkiewicz, M.; Turco, E.; Loefke, C.; Li, B.; Durnberger, G.; Schutzbier, M.; Chen, H. T.; Abdrakhmanov, A.; Savova, A.; Chia, K.-S.; Djamei, A.; Schaffner, I.; Abel, S.; Jiang, L.; Mechtler, K.; Ikeda, F.; Martens, S.; Clausen, T.; Dagdas, Y.
10.1101/2020.03.18.995316 — cell biology — Posted on 2020-03-24
1117 VADR: validation and annotation of virus sequence submissions to GenBank
Schäffer, A. A.; Hatcher, E.; Yankie, L.; Shonkwiler, L.; Brister, J. R.; Karsch-Mizrachi, I.; Nawrocki, E. P.
10.1101/852657 — bioinformatics — Posted on 2020-03-24
1120 High-amplitude co-fluctuations in cortical activity drive functional connectivity
Zamani Esfahlani, F.; Jo, Y.; Faskowitz, J.; Byrge, L.; Kennedy, D.; Sporns, O.; Betzel, R.
10.1101/800045 — neuroscience — Posted on 2020-03-24
1121 Bacterial Swarmers exhibit a Protective Response to Intestinal Stress
Chen, W.; De, A.; Li, H.; Lukin, D. J.; Szymczak, W.; Sun, K.; Kelly, L.; Wright, J. R.; Lamendella, R.; Ghosh, S.; Kearns, D. B.; He, Z.; Jobin, C.; Luo, X.; Byju, A.; Chatterjee, S.; Yeoh, B. S.; Vijay-Kumar, M.; Tang, J. X.; Mani, S.
10.1101/759886 — microbiology — Posted on 2020-03-24
1122 A technology-agnostic long-read analysis pipeline for transcriptome discovery and quantification
Wyman, D.; Balderrama-Gutierrez, G.; Reese, F.; Jiang, S.; Rahmanian, S.; Forner, S.; Matheos, D.; Zeng, W.; Williams, B. A.; Trout, D.; England, W.; Chu, S.; Spitale, R. C.; Tenner, A. J.; Wold, B.; Mortazavi, A.
10.1101/672931 — genomics — Posted on 2020-03-24
1124 Nature based measures increase freshwater biodiversity in agricultural catchments
Williams, P. J.; Biggs, J.; Stoate, C.; Szczur, J.; Brown, C.; Bonney, S.
10.1101/672915 — ecology — Posted on 2020-03-24
1125 Structural basis for EPC1-mediated recruitment of MBTD1 into the NuA4/TIP60 acetyltransferase complex
zhang, h.; Devoucoux, M.; li, l.; Ayaz, G.; cheng, h.; Tempel, W.; dong, c.; Loppnau, P.; Cote, J.; min, j.; song, x.
10.1101/746180 — biochemistry — Posted on 2020-03-24
1126 Establishment of Proximity-dependent Biotinylation Approaches in Different Plant Model Systems
Arora, D.; B. Abel, N.; Liu, C.; Van Damme, P.; Yperman, K.; Dai Vu, L.; Wang, J.; Tornkvist, A.; Impens, F.; Korbei, B.; Eeckhout, D.; Van Leene, J.; Goossens, A.; De Jaeger, G.; Ott, T.; Moschou, P.; Van Damme, D.
10.1101/701425 — plant biology — Posted on 2020-03-24
1129 Iatrogenic Iron Promotes Neurodegeneration and Activates Self-protection of Neural Cells against Exogenous Iron Attacks
Xia, M.; Liang, S.; Li, S.; Li, Z.; Zhang, M.; Chen, B.; Dong, C.; Chen, B.; Ji, M.; Gong, W.; Guan, D.; Verkhratsky, A.; Li, B.
10.1101/2020.03.21.001925 — neuroscience — Posted on 2020-03-24
1131 A long noncoding RNA, LOC157273, is the effector transcript at the chromosome 8p23.1-PPP1R3B metabolic traits and type 2 diabetes risk locus
Manning, A. K.; Goustin, A. S.; Kleinbrink, E.; Thepsuwan, P.; Cai, J.; Ju, D.; Leong, A.; Udler, M.; Brown, J. B.; Goodarzi, M. O.; Rotter, J. I.; Sladek, R.; Meigs, J. B.; Lipovich, L.
10.1101/2020.03.24.000620 — genomics — Posted on 2020-03-24
1132 Neural processing genes are linked to divergence in visual mate preference in sympatric Heliconius butterflies
Rossi, M.; Thurman, T. J.; Hausmann, A. E.; Montgomery, S. H.; Papa, R.; Jiggins, C. D.; Mcmillan, W. O.; Merrill, R. M.
10.1101/2020.03.22.002121 — evolutionary biology — Posted on 2020-03-24
1134 Designing Topographically Textured Microparticles For Induction and Modulation of Osteogenesis in Mesenchymal Stem Cell Engineering
Amer, M. H.; Alvarez-Paino, M.; McLaren, J.; Pappalardo, F.; Trujillo, S.; Wong, J. Q.; Shrestha, S.; Abdelrazig, S.; Lee, J. B.; Stevens, L.; Kim, D. H.; Gonzalez-Garcia, C.; Needham, D.; Salmeron-Sanchez, M.; Shakesheff, K. M.; Alexander, M. R.; Alexander, C.; Rose, F. R.
10.1101/2020.03.22.002279 — bioengineering — Posted on 2020-03-24
1136 BCKDK regulates the TCA cycle through PDC to ensure embryonic development in the absence of PDK family
Heinemann-Yerushalmi, L.; Bentovim, L.; Felsenthal, N.; Michaeli, N.; Krief, S.; Haffner-Krausz, R.; Ben-Dor, S.; Itkin, M.; Malitsky, S.; Silberman, A.; Erez, A.; Zelzer, E.
10.1101/2020.03.22.002360 — molecular biology — Posted on 2020-03-24
1141 Governance networks around grasslands with contrasting management history
Manolache, S.; Nita, A.; Hartel, T.; Miu, I. V.; Ciocanea, C. M.; Rozylowicz, L.
10.1101/2020.03.22.002352 — ecology — Posted on 2020-03-24
1146 The O2-independent pathway of ubiquinone biosynthesis is essential for denitrification in Pseudomonas aeruginosa
Vo, C.-D.-T.; Michaud, J.; Elsen, S.; Faivre, B.; Bouveret, E.; Barras, F.; Fontecave, M.; Pierrel, F.; Lombard, M.; Pelosi, L.
10.1101/2020.03.22.002311 — biochemistry — Posted on 2020-03-24
1148 Chronic antidepressant treatments rescue reduced REM sleep theta power in a rat social defeat stress model of depression
Matsuda, Y.; Ozawa, N.; Shinozaki, T.; Aoki, K.; Nihonmatsu-Kikuchi, N.; Shinba, T.; Tatebayashi, Y.
10.1101/2020.03.21.001164 — neuroscience — Posted on 2020-03-24
1149 F5N : Nanopore Sequence Analysis Toolkit for Android Smartphones
Samarakoon, H.; Punchihewa, S.; Senanayake, A.; Ragel, R.; Gamaarachchi, H.
10.1101/2020.03.22.002030 — bioinformatics — Posted on 2020-03-24
1153 SARS-CoV-2 launches a unique transcriptional signature from in vitro, ex vivo, and in vivo systems
Blanco-Melo, D.; Nilsson-Payant, B.; Liu, W.-C.; Moeller, R.; Panis, M.; Sachs, D.; Albrecht, R.; tenOever, B. R.
10.1101/2020.03.24.004655 — microbiology — Posted on 2020-03-24
1154 Emergence of SARS-CoV-2 through Recombination and Strong Purifying Selection
Li, X.; Giorgi, E. E.; Marichann, M. H.; Foley, B.; Xiao, C.; Kong, X.-p.; Chen, Y.; Korber, B.; Gao, F.
10.1101/2020.03.20.000885 — microbiology — Posted on 2020-03-24
1156 A glucose-stimulated BOLD fMRI study of hypothalamic dysfunction in mice fed a high-fat and high-sucrose diet
Mohr, A. A.; Garcia-Serrano, A. M.; Vieira, J. P. P.; Skoug, C.; Davidsson, H.; Duarte, J. M. N.
10.1101/2020.03.21.001149 — neuroscience — Posted on 2020-03-24
1160 In response to Li et al.: Linker histones function in Drosophila embryogenesis
Carbonell, A.; Henn, L.; Perez-Roldan, J.; Tamirisa, S.; Szabo, A.; Boros, I. M.; Azorin, F.
10.1101/2020.03.21.001529 — molecular biology — Posted on 2020-03-24
1161 Novel mosaic mice with diverse applications
Chi, T.; Sun, J.; Chen, Y.; Mao, S.; Liu, B.; Jing, Z.; Zang, Y.; Xia, J.
10.1101/2020.03.21.001388 — genetics — Posted on 2020-03-24
1162 Why not record from every electrode with a CMOS scanning probe?
Dimitriadis, G.; Neto, J. P.; Aarts, A.; Alexandru, A.; Ballini, M.; Battaglia, F.; Calcaterra, L.; Chen, S.; David, F.; Fiath, R.; Frazao, J.; Geerts, J. P.; Gentet, L. J.; Helleputte, N. V.; Holzhammer, T.; Hoof, C. v.; Horvath, D.; Lopes, G.; Lopez, C. M.; Maris, E.; Marques-Smith, A.; Marton, G.; McNaughton, B. L.; Meszena, D.; Mitra, S.; Musa, S.; Neves, H.; Nogueira, J.; Orban, G. A.; Pothof, F.; Putzeys, J.; Raducanu, B.; Ruther, P.; Schroeder, T.; Singer, W.; Steinmetz, N. A.; Tiesinga, P.; Ulbert, I.; Wang, S.; Welkenhuysen, M.; Kampff, A. R.
10.1101/275818 — neuroscience — Posted on 2020-03-24
1164 Adaptable pulsatile flow generated by quantitative imaging of stem-cell derived cardiomyocytes for disease modeling
Qian, T.; Gil, D. A.; Contreras Guzman, E.; Gastfriend, B. D.; Tweed, K. E.; Palecek, S. P.; Skala, M. C.
10.1101/2020.03.20.000752 — bioengineering — Posted on 2020-03-24
1169 Cortico-motor control dynamics orchestrates visual sampling
Tomassini, A.; Maris, E.; Hilt, P.; Fadiga, L.; D'Ausilio, A.
10.1101/2020.03.23.003228 — neuroscience — Posted on 2020-03-23
1170 CRISPR/Cpf1 mediated genome editing enhances Bombyx mori resistance to BmNPV
Dong, Z.; Qin, Q.; Hu, Z.; Zhang, X.; Miao, J.; Huang, L.; Chen, P.; Lu, C.; Pan, M.
10.1101/2020.03.23.003368 — microbiology — Posted on 2020-03-23
1173 Shifts in evolutionary balance of microbial phenotypes under environmental changes
Kleshnina, M.; McKerral, J. C.; Gonzalez-Tokman, C.; Filar, J. A.; Mitchell, J. G.
10.1101/2020.03.23.003343 — microbiology — Posted on 2020-03-23
1174 System-wide biochemical analysis reveals ozonide antimalarials initially act by disrupting Plasmodium falciparum haemoglobin digestion
Giannangelo, C.; Siddiqui, G.; De Paoli, A.; Anderson, B. M.; Edgington-Mitchell, L. E.; Charman, S. A.; Creek, D. J.
10.1101/2020.03.23.003376 — microbiology — Posted on 2020-03-23
1176 Deletion of FUNDC2 and CMC4 on chromosome Xq28 is sufficient to cause hypergonadotropic hypogonadism in men
Deng, X.; Fang, H.; Pathak, A.; Zou, A. M.; Neufeld-Kaiser, W.; Malouf, E. A.; Failor, R. A.; Hisama, F. M.; Liu, Y. J.
10.1101/2020.03.23.004424 — genomics — Posted on 2020-03-23
1177 "The Heidelberg Five" Personality Dimensions: Genome-wide Associations, Polygenic Risk for Neuroticism, and Psychopathology 20 Years after Assessment
Heilbronner, U.; Papiol, S.; Budde, M.; Andlauer, T. F. M.; Strohmaier, J.; Streit, F.; Frank, J.; Degenhardt, F.; Heilmann-Heimbach, S.; Witt, S.; Forstner, A. J.; Loerbroks, A.; Amelang, M.; Stuermer, T.; Mueller-Myhsok, B.; Noethen, M. M.; Rietschel, M.; Schulze, T. G.
10.1101/2020.03.23.003889 — genomics — Posted on 2020-03-23
1178 CTCF Promotes Long-range Enhancer-promoter Interactions and Lineage-specific Gene Expression in Mammalian Cells
Kubo, N.; Ishii, H.; Xiong, X.; Bianco, S.; Meitinger, F.; Hu, R.; Hocker, J. D.; Conte, M.; Gorkin, D.; Yu, M.; Li, B.; Dixon, J.; Hu, M.; Nicodemi, M.; Zhao, H.; Ren, B.
10.1101/2020.03.21.001693 — genomics — Posted on 2020-03-23
1180 Whole Genome Sequencing of Plasmodium vivax Isolates Reveals Frequent Sequence and Structural Polymorphisms in Erythrocyte Binding Genes
Ford, A.; Kepple, D.; Abagero, B. R.; Connors, J.; Pearson, R.; Auburn, S.; Getachew, S.; Ford, C.; Gunalan, K.; Miller, L.; Janies, D.; Rayner, J.; Yan, G.; Yewhalaw, D.; Lo, E.
10.1101/2020.03.23.003293 — genomics — Posted on 2020-03-23
1182 Dmon1 and rab7 interact to regulate glutamate receptor GluRIIA levels at the larval Drosophila neuromuscular junction.
Basargekar, A. S.; Yogi, S.; Mushtaq, Z.; Deivasigamani, S.; Kumar, V.; Ratnaparkhi, G. S.; Ratnaparkhi, A.
10.1101/2020.03.21.999524 — genetics — Posted on 2020-03-23
1188 Epigenetic regulation of Neuregulin-1 tunes white adipose stem cell differentiation
Cordero, A. D.; Callihan, E. C.; Said, R.; Alowais, Y.; Paffhausen, E. S.; Bracht, J. R.
10.1101/2020.03.23.004275 — cell biology — Posted on 2020-03-24
1191 Hypersilencing of SRRM4 suppresses basal microexon inclusion and promotes tumor growth across cancers
Head, S. A.; Hernandez-Alias, X.; Yang, J.-S.; Beltran-Sastre, V.; Torres-Mendez, A.; Irimia, M.; Schaefer, M. H.; Serrano, L.
10.1101/2020.03.23.003574 — cancer biology — Posted on 2020-03-24
1196 Genome-wide prediction of topoisomerase IIβ binding by architectural factors and chromatin accessibility
Cortes-Ledesma, F.; Martinez-Garcia, P. M.; Garcia-Torres, M.; Divina, F.; Terron-Bautista, J.; Delgado-Sainz, I.; Gomez-Vela, F.
10.1101/2020.03.23.003277 — bioinformatics — Posted on 2020-03-23
1197 Benchmarking accuracy and precision of intensity-based absolute quantification of protein abundances in Saccharomyces cerevisiae
Sanchez, B. J.; Lahtvee, P.-J.; Campbell, K.; Kasvandik, S.; Yu, R.; Domenzain, I.; Zelezniak, A.; Nielsen, J.
10.1101/2020.03.23.998237 — bioinformatics — Posted on 2020-03-24
1198 A generative algorithm for de novo design of proteins with diverse pocket structures
Basanta, B.; Bick, M. J.; Bera, A. K.; Norn, C.; Chow, C. M.; Carter, L. P.; Goreshnick, I.; Dimaio, F.; Baker, D.
10.1101/2020.03.23.003913 — biochemistry — Posted on 2020-03-24
1201 Characterizing the Human Heart Rate Circadian Pacemaker through Widely Available Wearable Devices
Bowman, C.; Huang, Y.; Walch, O. J.; Fang, Y.; Frank, E.; Goldstein, C.; Sen, S.; Forger, D. B.
10.1101/2020.03.12.988899 — systems biology — Posted on 2020-03-24
1202 Clustering by phenotype and genome-wide association study in autism
Narita, A.; Nagai, M.; Mizuno, S.; Ogishima, S.; Tamiya, G.; Ueki, M.; Sakurai, R.; Makino, S.; Obara, T.; Ishikuro, M.; Yamanaka, C.; Matsubara, H.; Kuniyoshi, Y.; Murakami, K.; Ueno, F.; Noda, A.; Kobayashi, T.; Kobayashi, M.; Usuzaki, T.; Ohseto, H.; Hozawa, A.; Kikuya, M.; Metoki, H.; Kure, S.; Kuriyama, S.
10.1101/614958 — neuroscience — Posted on 2020-03-24
1204 Cross-species transcriptomic and epigenomic analysis reveals key regulators of injury response and neuronal regeneration in vertebrate retinas.
Hoang, T.; Wang, J.; Boyd, P.; Wang, F.; Santiago, C.; Jiang, L.; Lahne, M.; Todd, L.; Saez, C.; Yoo, S.; Keuthan, C.; Palazzo, I.; Squires, N.; Campbell, W.; Jia, M.; Rajaii, F.; Parayil, T.; Trinh, V.; Kim, D. W.; Wang, G.; Ash, J.; Fischer, A.; Hyde, D.; Qian, J.; Blackshaw, S.
10.1101/717876 — neuroscience — Posted on 2020-03-23
1205 Incipient resistance to an effective pesticide results from genetic adaptation and the canalization of gene expression
Yin, X.; Martinez, A. S.; Perkins, A.; Sparks, M. M.; Harder, A. M.; Willoughby, J. R.; Sepulveda, M. S.; Christie, M. R.
10.1101/2019.12.19.882860 — genetics — Posted on 2020-03-23
1210 The Role of Potassium and Host Calcium Signaling in Toxoplasma gondii egress
Vella, S. A.; Moore, C. A.; Li, Z.-H.; Hortua Triana, M. A.; Potapenko, E.; Moreno, S. N.
10.1101/2020.03.06.980508 — microbiology — Posted on 2020-03-23
1211 Testing Structural Models of Psychopathology at the Genomic Level
Waldman, I. D.; Poore, H. E.; Luningham, J. M.; Yang, J.
10.1101/502039 — genomics — Posted on 2020-03-23
1214 The immune vulnerability landscape of the 2019 Novel Coronavirus, SARS-CoV-2
Zhu, J.; Kim, J.; Xiao, X.; Wang, Y.; Luo, D.; Chen, R.; Xu, L.; Zhang, H.; Xiao, G.; Schoggins, J.; Zhan, X.; Wang, T.; Xie, Y.
10.1101/2020.02.08.939553 — bioinformatics — Posted on 2020-03-23
1216 A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
Gordon, D. E.; Jang, G. M.; Bouhaddou, M.; Xu, J.; Obernier, K.; O'Meara, M. J.; Guo, J. Z.; Swaney, D. L.; Tummino, T. A.; Huttenhain, R.; Kaake, R.; Richards, A. L.; Tutuncuoglu, B.; Foussard, H.; Batra, J.; Haas, K.; Modak, M.; Kim, M.; Haas, P.; Polacco, B. J.; Braberg, H.; Fabius, J. M.; Eckhardt, M.; Soucheray, M.; Brewer, M.; Cakir, M.; McGregor, M. J.; Li, Q.; Naing, Z. Z. C.; Zhou, Y.; Peng, S.; Kirby, I. T.; Melnyk, J. E.; Chorba, J. S.; Lou, K.; Dai, S. A.; Shen, W.; Shi, Y.; Zhang, Z.; Barrio-Hernandez, I.; Memon, D.; Hernandez-Armenta, C.; Mathy, C. J. P.; Perica, T.; Pilla, K. B.
10.1101/2020.03.22.002386 — systems biology — Posted on 2020-03-23
1221 Genomic Surveillance of Neisseria gonorrhoeae in the Philippines from 2013-2014
Villamin, A. S.; Argimon, S.; Jamoralin, M. C.; Boehme, K. D.; Masim, M. L.; Gayeta, J. M.; Lagrada, M. L.; Olorosa, A. M.; Cohen, V.; Hernandez, L. T.; Jeffrey, B.; Abudahab, K.; Hufano, C. M.; Sia, S. B.; Stelling, J.; Holden, M. T. G.; Aanensen, D. M.; Carlos, C. C.; on behalf of the Philippines Antimicrobial Resistance Surveillance Program,
10.1101/2020.03.19.998435 — genomics — Posted on 2020-03-23
1229 A new method of Bayesian causal inference in non-stationary environments
Shinohara, S.; Manome, N.; Suzuki, K.; Chung, U.-i.; Takahashi, T.; Okamoto, H.; Gunji, Y.; Nakajima, Y.; Mitsuyoshi, S.
10.1101/861096 — animal behavior and cognition — Posted on 2020-03-23
1231 Real brains in virtual worlds: Validating a novel oddball paradigm in virtual reality
Kuziek, J. W. P.; Tayem, A. R.; Burrell, J.; Redman, E. X.; Murray, J.; Reinan, J.; Sipolins, A.; Mathewson, K. E.
10.1101/749192 — neuroscience — Posted on 2020-03-23
1232 Temporal dynamics of visual representations in the infant brain
Bayet, L.; Zinszer, B. D.; Reilly, E.; Cataldo, J. K.; Pruitt, Z.; Cichy, R. M.; Nelson, C. A.; Aslin, R. N.
10.1101/2020.02.26.947911 — neuroscience — Posted on 2020-03-23
1233 Protrudin functions as a scaffold in the endoplasmic reticulum to support axon regeneration in the adult central nervous system
Petrova, V.; Pearson, C. S.; Tribble, J. R.; Solano, A. G.; Reid, E.; Geller, H. M.; Williams, P. A.; Eva, R.; Fawcett, J. W.
10.1101/2020.01.15.907550 — neuroscience — Posted on 2020-03-23
1236 Cortical cell stiffness is independent of substrate mechanics
Rheinlaender, J.; Dimitracopoulos, A.; Wallmeyer, B.; Kronenberg, N. M.; Chalut, K. J.; Gather, M. C.; Betz, T.; Charras, G. T.; Franze, K.
10.1101/829614 — biophysics — Posted on 2020-03-23
1238 Development of Nanobodies as first-in-class inhibitors for the NEDP1 deNEDDylating enzyme
Xirodimas, D.; Abidi, N.; Pugniere, M.; Muyldermans, S.; Trauchessec, H.; Hassanzadeh-Ghassabeh, G.
10.1101/2020.03.20.999326 — molecular biology — Posted on 2020-03-23
1239 celldeath: a tool for simple detection of cell death in transmitted light microscopy images by visual deep learning analysis
La Greca, A.; Perez, N.; Milone, P. M.; Castaneda, S.; Scarafia, M. A.; Möbbs, A. M.; Waisman, A.; Moro, L. N.; Sevlever, G.; Luzzani, C.; Miriuka, S. G.
10.1101/2020.03.22.002253 — cell biology — Posted on 2020-03-23
1241 CHOmics: a web-based tool for multi-omics data analysis and interactive visualization in CHO cell lines
Lin, D.; Yalamanchili, H.; Zhang, X.; Lewis, N. E.; Alves, C. S.; Groot, J.; Arnsdorf, J.; Peterson Bjorn, S.; Wulff, T.; Rude Voldborg, B. G.; Zhou, Y.; Zhang, B.
10.1101/2020.03.17.995290 — bioinformatics — Posted on 2020-03-23
1244 Left prefrontal impact links subthalamic stimulation with depressive symptoms
Irmen, F.; Horn, A.; Mosley, P.; Perry, A.; Petry-Schmelzer, J. N.; Dafsari, H.; Barbe, M.; Visser-Vandewalle, V.; Schneider, G.-H.; Li, N.; Kübler, D.; Wenzel, G.; Kühn, A. A.
10.1101/665976 — neuroscience — Posted on 2020-03-23
1248 A role for KIF9 in male fertility
Chen, K.; Cho, S. Y.; Zhang, Y.; Beck, A.; Segall, J. E.
10.1101/2020.03.21.001602 — developmental biology — Posted on 2020-03-23
1250 Senescent stromal cells promote cancer resistance through SIRT1 loss-potentiated overproduction of small extracellular vesicles
Han, L.; Long, Q.; Li, S.; Xu, Q.; Zhang, B.; Dou, X.; Qian, M.; Jiramongkol, Y.; Guo, J.; Cao, L.; Chin, E.; Lam, E.; Jiang, J.; Sun, Y.
10.1101/2020.03.22.002667 — cell biology — Posted on 2020-03-23
1252 Dynamic Sex Chromosome Expression in Drosophila Male Germ Cells
Mahadevaraju, S.; Fear, J. M.; Akeju, M.; Galletta, B. J.; Pinheiro, M. M.; Avelino, C. C.; Cabral-de-Mello, D. C.; Conlon, K.; Dell'Orso, S.; Demere, Z.; Mansuria, K.; Mendonca, C. A.; Palacios-Gimenez, O. M.; Ross, E.; Savery, M.; Yu, K.; Smith, H. E.; Sartorelli, V.; Rusan, N. M.; Vibranovski, M. D.; Matunis, E.; Oliver, B.
10.1101/2020.03.23.000356 — developmental biology — Posted on 2020-03-23
1258 In Silico Analysis of B3GALTL Gene Reveling 13 Novel Mutations Associated with Peters'-plus syndrome
abdelmoneim, a. h.; Satti, A. A.; Abdelmageed, M. I.; Murshed, N. S.; Elfadol, N. M.; Mustafa, M. I.; Makhawi, A. M.
10.1101/2020.03.21.000695 — bioinformatics — Posted on 2020-03-23
1260 Naturally occurring cobalamin (B12) analogs can function as cofactors for human methylmalonyl-CoA mutase
Sokolovskaya, O. M.; Plessl, T.; Bailey, H.; Mackinnon, S.; Baumgartner, M. R.; Yue, W. W.; Froese, D. S.; Taga, M. E.
10.1101/2020.03.20.997551 — biochemistry — Posted on 2020-03-23
1261 A comparative analysis reveals irreproducibility in searches of scientific literature
Pozsgai, G.; Lovei, G.; Vasseur, L.; Gurr, G.; Batary, P.; Korponai, J.; Littlewood, N. A.; Liu, J.; Mora, A.; Obrycki, J.; Reynolds, O.; Stockan, J. A.; VanVolkenburg, H.; Zhang, J.; Zhou, W.; You, M.
10.1101/2020.03.20.997783 — scientific communication and education — Posted on 2020-03-23
1262 Deletion of calcineurin from astrocytes reproduces proteome signature of Alzheimer's disease and epilepsy and predisposes to seizures
Tapella, L.; Dematteis, G.; Ruffinatti, F. A.; Ponzoni, L.; Fiordaliso, F.; Corbelli, A.; Albanese, E.; Pistolato, B.; Pagano, J.; Barberis, E.; Marengo, E.; Balducci, C.; Forloni, G.; Verpelli, C.; Sala, C.; Distasi, C.; Sala, M.; Genazani, A. A.; Manfredi, M.; Lim, D.
10.1101/2020.03.21.001321 — neuroscience — Posted on 2020-03-23
1268 Potentiating the anti-tumor response of tumor infiltrated T cells by NAD+ supplementation
Wang, Y.; Wang, F.; Wang, L.; Qiu, S.; Yao, Y.; Xiong, X.; Chen, X.; Ji, Q.; Cao, J.; Li, D.; Zhang, L.; Wang, R.; Wang, H.; Fan, G.
10.1101/2020.03.21.001123 — immunology — Posted on 2020-03-23
1269 High resolution spatial transcriptome analysis by photo-isolation chemistry
Honda, M.; Oki, S.; Harada, A.; Maehara, K.; Tanaka, K.; Meno, C.; Ohkawa, Y.
10.1101/2020.03.20.000984 — genomics — Posted on 2020-03-23
1270 Pyronaridine Tetraphosphate Efficacy Against Ebola Virus Infection in Guinea Pig
Lane, T. R.; Massey, C.; Comer, J. E.; Freiberg, A. N.; Zhou, H.; Dyall, J.; Holbrook, M.; Anantpadma, M.; Davey, R. A.; Madrid, P.; Ekins, S.
10.1101/2020.03.20.001081 — pharmacology and toxicology — Posted on 2020-03-23
1273 Mouse-specific but infection-unspecific IgM repertoire fingerprint following viral infection
Yermanos, A.; Krautler, N. J.; Pedrioli, A.; Menzel, U.; Greiff, V.; Stadler, T.; Oxenius, A.; Reddy, S. T.
10.1101/2020.03.20.000471 — immunology — Posted on 2020-03-23
1274 Convergence within divergence: insights of wheat adaptation from Triticum population sequencing
Zhou, Y.; Zhao, X.; Li, Y.; Xu, J.; Bi, A.; Kang, L.; Chen, H.; Wang, Y.; Wang, Y.-g.; Liu, S.; Jiao, C.; Lu, H.; Wang, J.; Yin, C.; Jiao, Y.; Lu, F.
10.1101/2020.03.21.001362 — genetics — Posted on 2020-03-23
1277 Diversified regulation of circadian clock gene expression following whole genome duplication
West, A. C.; Iversen, M.; Jorgensen, E. H.; Sandve, S. R.; Hazlerigg, D. G.; Wood, S. H.
10.1101/2020.03.22.002162 — physiology — Posted on 2020-03-23
1279 Insights on the taxonomy and ecogenomics of the Synechococcus collective
Salazar, V. W.; Thompson, C. C.; Tschoeke, D. A.; Swings, J.; Mattoso, M.; Thompson, F. L.
10.1101/2020.03.20.999532 — microbiology — Posted on 2020-03-23
1282 Structural determinants of persulfide-sensing specificity in a dithiol-based transcriptional regulator
Capdevila, D. A.; Walsh, B. J. C.; Zhang, Y.; Dietrich, C. M.; Gonzalez-Gutierrez, G.; Giedroc, D. P.
10.1101/2020.03.22.001966 — biochemistry — Posted on 2020-03-23
1284 A mechanism for sensing of and adaptation to K+ deprivation in plants
Wang, F.-L.; Tan, Y.-L.; Wallrad, L.; Du, X.-Q.; Eickelkamp, A.; Wang, Z.-F.; He, G.-F.; Han, J.-P.; Schmitz-Thom, I.; Wu, W.-H.; Kudla, J.; Wang, Y.
10.1101/2020.03.21.000570 — plant biology — Posted on 2020-03-23
1286 A functional non-coding RNA is produced from xbp-1 mRNA
Liu, X.; Beaudoin, J.-D.; Davison, C. A.; Kosmaczewski, S. G.; Meyer, B. I.; Giraldez, A. J.; Hammarlund, M.
10.1101/2020.03.20.000869 — neuroscience — Posted on 2020-03-23
1290 LPS induces GFAT2 expression to promote O-GlcNAcylation and attenuate inflammation in macrophages
Al-Mukh, H.; Baudoin, L.; Bouaboud, A.; Sanchez-Salgado, J.-L.; Maraqa, N.; Khair, M.; Pagesy, P.; Bismuth, G.; Niedergang, F.; Issad, T.
10.1101/2020.03.22.002303 — biochemistry — Posted on 2020-03-23
1291 Profiling virus-specific Tcf1+ T cell repertoires during acute and chronic viral infection
Yermanos, A.; Sandu, I.; Pedrioli, A.; Borsa, M.; Wagen, F.; Oetiker, N.; Welten, S. P. M.; Pallmer, K.; Reddy, S. T.; Oxenius, A.
10.1101/2020.03.20.000646 — immunology — Posted on 2020-03-23
1295 Remote Ischemic Preconditioning Ameliorates Anthracycline-induced Cardiotoxicity and Preserves Mitochondrial Integrity
Galan-Arriola, C.; Villena-Gutierrez, R.; Higuero-Verdejo, M. I.; Diaz-Rengifo, I. A.; Pizarro, G.; Lopez, G. J.; de Molina-Iracheta, A.; Perez-Martinez, C.; Garcia, R. D.; Gonzalez-Calle, D.; Lobo, M.; Sanchez, P. L.; Oliver, E.; Cordoba, R.; Fuster, V.; Sanchez-Gonzalez, J.; Ibanez, B.
10.1101/2020.03.20.000729 — molecular biology — Posted on 2020-03-23
1297 Limits to flow detection in pulsed gradient spin echo NMR
Williamson, N. H.; Komlosh, M. E.; Benjamini, D.; Basser, P. J.
10.1101/2020.03.20.000638 — biophysics — Posted on 2020-03-23
1298 IMPLICON: an ultra-deep sequencing method to uncover DNA methylation at imprinted regions
Klobucar, T.; Kreibich, E.; Krueger, F.; Arez, M.; Polvora-Brandao, D.; von Meyenn, F.; da Rocha, S. T.; Eckersley-Maslin, M. A.
10.1101/2020.03.21.000042 — molecular biology — Posted on 2020-03-23
1302 Genetic analyses identify widespread sex-differential participation bias
Pirastu, N.; Cordioli, M.; Nandakumar, P.; Mignogna, G.; Abdellaoui, A.; Hollis, B.; Kanai, M.; Rajagopal, V. M.; Della Briotta Parolo, P.; Baya, N.; Carey, C.; Karjalainen, J.; Als, T. D.; van der Zee, M. D.; Day, F. R.; Ong, K. K.; 23andMe Research Team, ; iPSYCH Consortium, ; Morisaki, T.; de Geus, E.; Bellocco, R.; Okada, Y.; Borglum, A.; Joshi, P. K.; Auton, A.; Hinds, D. K.; Neale, B.; Walters, R. K.; Nivard, M. G.; Perry, J.; Ganna, A.
10.1101/2020.03.22.001453 — genetics — Posted on 2020-03-23
1303 Translational adaptation to heat stress is mediated by 5-methylcytosine RNA modification in Caenorhabditis elegans
Navarro, I. C.; Tuorto, F.; Jordan, D.; Legrand, C.; Price, J.; Braukmann, F.; Hendrick, A.; Akay, A.; Kotter, A.; Helm, M.; Lyko, F.; Miska, E. A.
10.1101/2020.03.21.001735 — genetics — Posted on 2020-03-23
1306 Phylogenomic analysis clarifies the evolutionary origin of Coffea arabica L.
Bawin, Y.; Ruttink, T.; Staelens, A.; Haegeman, A.; Stoffelen, P.; Mwanga Mwanga, J.-C. I.; Roldan-Ruiz, I.; Honnay, O.; Janssens, S.
10.1101/2020.03.22.002337 — evolutionary biology — Posted on 2020-03-23
1310 BK polyomavirus evades innate immune sensing by disrupting the mitochondrial network and membrane potential and by promoting mitophagy
Manzetti, J.; Weissbach, F. H.; Unterstab, G.; Wernli, M.; Hopfer, H.; Drachenberg, C. B.; Rinaldo, C. H.; Hirsch, H. H.
10.1101/2020.03.19.994988 — microbiology — Posted on 2020-03-23
1312 Identification of antiviral drug candidates against SARS-CoV-2 from FDA-approved drugs
Jeon, S.; Ko, M.; Lee, J.; Choi, I.; Byun, S. Y.; Park, S.; Shum, D.; Kim, S.
10.1101/2020.03.20.999730 — microbiology — Posted on 2020-03-23
1313 Quality assessment of single-cell RNA sequencing data by coverage skewness analysis
Abugessaisa, I.; Noguchi, S.; Cardon, M.; Hasegawa, A.; Watanabe, K.; Takahashi, M.; Suzuki, H.; Katayama, S.; Kere, J.; Kasukawa, T.
10.1101/2019.12.31.890269 — genomics — Posted on 2020-03-23
1314 Improving tuberculosis surveillance by detecting international transmission using publicly available whole-genome sequencing data
Sanchini, A.; Jandrasits, C.; Tembrockhaus, J.; Kohl, T. A.; Utpatel, C.; Maurer, F. P.; Niemann, S.; Haas, W.; Renard, B. Y.; Kroeger, S.
10.1101/834150 — microbiology — Posted on 2020-03-23
1315 celldeath: a tool for simple detection of cell death in transmitted light microscopy images by visual deep learning analysis
La Greca, A.; Perez, N.; Milone, P. M.; Castaneda, S.; Scarafia, M. A.; Möbbs, A. M.; Waisman, A.; Moro, L. N.; Sevlever, G.; Luzzani, C.; Miriuka, S. G.
10.1101/2020.03.22.002253 — cell biology — Posted on 2020-03-23
1318 Automated cot-side tracking of functional brain age in preterm infants
Stevenson, N. J.; Oberdorfer, L.; Tataranno, M.-L.; Breakspear, M.; Colditz, P. B.; de Vries, L. S.; Benders, M. J.; Klebermass-Schrehof, K.; Vanhatalo, S.; Roberts, J. A.
10.1101/848218 — neuroscience — Posted on 2020-03-23
1319 Parsing multiomics landscape of activated synovial fibroblasts highlights drug targets linked to genetic risk of rheumatoid arthritis
Tsuchiya, H.; Ota, M.; Sumitomo, S.; Ishigaki, K.; Suzuki, A.; Sakata, T.; Tsuchida, Y.; Inui, H.; Hirose, J.; Kochi, Y.; Kadono, Y.; Shirahige, K.; Tanaka, S.; Yamamoto, K.; Fujio, K.
10.1101/861781 — immunology — Posted on 2020-03-23
1321 A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
Gordon, D. E.; Jang, G. M.; Bouhaddou, M.; Xu, J.; Obernier, K.; O'Meara, M. J.; Guo, J. Z.; Swaney, D. L.; Tummino, T. A.; Huttenhain, R.; Kaake, R.; Richards, A. L.; Tutuncuoglu, B.; Foussard, H.; Batra, J.; Haas, K.; Modak, M.; Kim, M.; Haas, P.; Polacco, B. J.; Braberg, H.; Fabius, J. M.; Eckhardt, M.; Soucheray, M.; Brewer, M.; Cakir, M.; McGregor, M. J.; Li, Q.; Naing, Z. Z. C.; Zhou, Y.; Peng, S.; Kirby, I. T.; Melnyk, J. E.; Chorba, J. S.; Lou, K.; Dai, S. A.; Shen, W.; Shi, Y.; Zhang, Z.; Barrio-Hernandez, I.; Memon, D.; Hernandez-Armenta, C.; Mathy, C. J. P.; Perica, T.; Pilla, K. B.
10.1101/2020.03.22.002386 — systems biology — Posted on 2020-03-22
1323 RNA editing enzyme APOBEC3A promotes pro-inflammatory (M1) macrophage polarization
Alqassim, E. Y.; Sharma, S.; Khan, A. N. H.; Emmons, T.; Cortes-Gomez, E.; Singel, K.; Mark, J.; Davidson, B. A.; McGray, A. R.; Litchy, B. D.; Moysich, K.; Wang, J.; Odunsi, K.; Segal, B. H.; Baysal, B. E.
10.1101/2020.03.20.988980 — immunology — Posted on 2020-03-22
1330 Emergence of SARS-CoV-2 through Recombination and Strong Purifying Selection
Li, X.; Giorgi, E. E.; Marichann, M. H.; Foley, B.; Xiao, C.; Kong, X.-p.; Chen, Y.; Korber, B.; Gao, F.
10.1101/2020.03.20.000885 — microbiology — Posted on 2020-03-22
1332 True S-cones are concentrated in the ventral mouse retina for color detection in the upper visual field
Li, W.; Nadal-Nicolas, F. M.; Kunze, V. P.; Ball, J. M.; Peng, B. T.; Krishnan, A.; Zhou, G.; Dong, L.
10.1101/2020.03.20.999979 — evolutionary biology — Posted on 2020-03-22
1335 Detection and skeletonization of single neurons and tracer injections using topological methods
Wang, D.; Magee, L.; Huo, B.-X.; Banerjee, S.; Li, X.; Jayakumar, J.; Lin, M. K.; Ram, K.; Wang, S.; Wang, Y.; Mitra, P. P.
10.1101/2020.03.21.000323 — neuroscience — Posted on 2020-03-22
1339 Analysis of Plasmodium vivax schizont transcriptomes from field isolates reveals heterogeneity of expression of genes involved in host-parasite interactions
Siegel, S. V.; Chappell, L.; Hostetler, J. B.; Amaratunga, C.; Suon, S.; Bohme, U.; Berriman, M.; Fairhurst, R. M.; Rayner, J. C.
10.1101/2020.03.20.998294 — genomics — Posted on 2020-03-22
1340 Metabolite Quantitative Trait Loci for flavonoids provide new insights into the genetic architecture of strawberry (Fragaria x ananassa) fruit quality
Labadie, M.; Vallin, G.; Petit, A.; Ring, L.; Hoffmann, T.; Gaston, A.; Potier, A.; Schwab, W.; Rothan, C.; Denoyes, B.
10.1101/2020.03.20.000455 — genetics — Posted on 2020-03-22
1343 Improving the accessibility and transferability of machine learning algorithms for identification of animals in camera trap images: MLWIC2
Tabak, M. A.; Norouzzadeh, M. S.; Wolfson, D. W.; Newton, E. J.; Boughton, R. K.; Ivan, J. S.; Odell, E. A.; Newkirk, E. S.; Conrey, R. Y.; Stenglein, J.; Iannarilli, F.; Erb, J.; Brook, R. K.; Davis, A. J.; Lewis, J.; Walsh, D. P.; Beasley, J. C.; VerCauteren, K. C.; Clune, J.; Miller, R. S.
10.1101/2020.03.18.997700 — ecology — Posted on 2020-03-22
1346 Altered structure and stability of bat-prey interaction networks in logged tropical forests revealed by metabarcoding
Hemprich-Bennett, D. R.; Kemp, V. A.; Blackman, J.; Struebig, M. J.; Lewis, O. T.; Rossiter, S. J.; Clare, E. L.
10.1101/2020.03.20.000331 — ecology — Posted on 2020-03-22
1349 Iodine staining as a useful probe for distinguishing amyloid fibril polymorphs
Hiramatsu, T.; Yamamoto, N.; Ha, S.; Masuda, Y.; Yasuda, M.; Ishigaki, M.; Yuzu, K.; Ozaki, Y.; Chatani, E.
10.1101/2020.03.21.001214 — biochemistry — Posted on 2020-03-22
1351 Selective inhibitors of SIRT2 regulate perinuclear α-tubulin acetylation, migration, and invasion of breast cancer cells
Nielsen, A. L.; Rajabi, N.; Kudo, N.; Larsen, K. L.; Fontenas, M.; Lucidi, A.; Madsen, A. S.; Yoshida, M.; Olsen, C. A.
10.1101/2020.03.20.000380 — biochemistry — Posted on 2020-03-22
1354 In vivo validation of spray-dried mesoporous bioactive glass microspheres acting as prolonged local release systems for BMP-2 to induce bone regeneration
Berkmann, J. C.; Herrera Martin, A. X.; Pontremoli, C.; Zheng, K.; Bucher, C. H.; Ellinghaus, A.; Boccaccini, A. R.; Fiorilli, S.; Vitale-Brovarone, C.; Duda, G. N.; Schmidt-Bleek, K.
10.1101/2020.03.21.001404 — cell biology — Posted on 2020-03-22
1355 Exploring Chromosomal Structural Heterogeneity AcrossMultiple Cell Lines
Cheng, R. R.; Contessoto, V.; Aiden, E. L.; Wolynes, P. G.; Di Pierro, M.; Onuchic, J. N.
10.1101/2020.03.21.001917 — biophysics — Posted on 2020-03-22
1356 BET inhibition induces an anti-apoptotic adaptive response and therapeutic vulnerability to MCL1 inhibitors in breast cancer
Yan, G.; Wang, H.; Luna, A.; Bozorgui, B.; Li, X.; Dereli, Z.; Chen, X.; Lu, Y.; Babur, O.; Sander, C.; Mills, G.; Korkut, A.
10.1101/711895 — cancer biology — Posted on 2020-03-21
1357 Population sequencing enhances understanding of tea plant evolution
Wang, X.; Feng, H.; Chang, Y.; Ma, C.; Wang, L.; Hao, X.; Li, A.; Cheng, H.; Wang, L.; Cui, P.; Jin, J.; Wang, X.; Wei, K.; Ai, C.; Wu, Z.; Zhao, S.; Li, Y.; Liu, B.; Wang, G.; Chen, L.; Ruan, J.; Yang, Y.
10.1101/2020.03.19.998393 — genomics — Posted on 2020-03-21
1360 A new FRET biosensor enlightens cAMP signalling in budding yeast
Botman, D.; O'Toole, T. G.; Goedhart, J.; Bruggeman, F.; van Heerden, J. H.; Teusink, B.
10.1101/831354 — microbiology — Posted on 2020-03-21
1361 Chemoreceptor pleiotropy facilitates the functional coupling of the synthesis and perception of mating pheromones
Zelle, K.; Vernier, C.; Leitner, N.; Liang, X.; Halloran, S.; Millar, J.; Ben-Shahar, Y.
10.1101/124305 — genetics — Posted on 2020-03-21
1362 Changes in perilesional V1 underlie training-induced recovery in cortically-blind patients
Barbot, A.; Das, A.; Melnick, M. D.; Cavanaugh, M. R.; Merriam, E. P.; Heeger, D. J.; Huxlin, K. R.
10.1101/2020.02.28.970285 — neuroscience — Posted on 2020-03-21
1369 First description of a herpesvirus infection in genus Lepus
Abade dos Santos, F. A.; Monteiro, M.; Pinto, A.; Carvalho, C. L.; Peleteiro, M. C.; Carvalho, P.; Mendonca, P.; Carvalho, T.; Duarte, M. D.
10.1101/2020.01.21.913723 — microbiology — Posted on 2020-03-21
1372 Brain computation by assemblies of neurons
Papadimitriou, C.; Vempala, S.; Mitropolsky, D.; Collins, M.; Maass, W.
10.1101/869156 — neuroscience — Posted on 2020-03-21
1374 Molecular characterization of SARS-CoV-2 in the first COVID-19 cluster in France reveals an amino-acid deletion in nsp2 (Asp268Del)
Bal, A.; Destras, G.; Gaymard, A.; Bouscambert-Duchamp, M.; Valette, M.; Escuret, V.; Frobert, E.; Billaud, G.; Trouillet-Assant, S.; Cheynet, V.; Brengel-Pesce, K.; Morfin, F.; Lina, B.; Josset, L.
10.1101/2020.03.19.998179 — microbiology — Posted on 2020-03-21
1375 Respiratory disease and virus shedding in rhesus macaques inoculated with SARS-CoV-2
Munster, V.; Feldmann, F.; Williamson, B.; van Doremalen, N.; Perez-Perez,, L.; Schultz, J.; Meade-White, K.; Okumura, A.; Callison, J.; Brumbaugh, B.; Avanzato, V.; Rosenke, R.; Hanley, P.; Saturday, G.; Scott, D.; Fischer, E.; de Wit, E.
10.1101/2020.03.21.001628 — microbiology — Posted on 2020-03-21
1378 Replication of SARS-CoV-2 in human respiratory epithelium
Milewska, A.; Kula-Pacurar, A.; Wadas, J.; Suder, A.; Szczepanski, A.; Dabrowska, A.; Owczarek, K.; Ochman, M.; Stacel, T.; Rajfur, Z.; Labaj, P. P.; Branicki, W.; Pyrc, K.
10.1101/2020.03.20.999029 — microbiology — Posted on 2020-03-21
1379 RT-qPCR DETECTION OF SARS-CoV-2 RNA FROM PATIENT NASOPHARYNGEAL SWAB USING QIAGEN RNEASY KITS OR DIRECTLY VIA OMISSION OF AN RNA EXTRACTION STEP
Bruce, E. A.; Tighe, S.; Hoffman, J. J.; Laaguiby, P.; Gerrard, D. L.; Diehl, S. A.; Leonard, D. G. B.; Huston, C. D.; Kirkpatrick, B. D.; Crothers, J. W.; Dragon, J.; Botten, J. W.
10.1101/2020.03.20.001008 — microbiology — Posted on 2020-03-21
1380 COVID-19 Vaccine Candidates: Prediction and Validation of 174 SARS-CoV-2 Epitopes
Prachar, M.; Justesen, S.; Steen-Jensen, D. B.; Thorgrimsen, S. P.; Jurgons, E.; Winther, O.; Bagger, F. O.
10.1101/2020.03.20.000794 — immunology — Posted on 2020-03-21
1381 Candidatus Ethanoperedens, a thermophilic genus of archaea mediating the anaerobic oxidation of ethane
Hahn, C. J.; Laso-Perez, R.; Volcano, F.; Vaziourakis, K.-M.; Stokke, R.; Steen, I. H.; Teske, A.; Boetius, A.; Liebeke, M.; Amann, R.; Knittel, K.; Wegener, G.
10.1101/2020.03.21.999862 — microbiology — Posted on 2020-03-21
1383 Ciliation of muscle stem cells is critical to maintain regenerative capacity and is lost during aging
Palla, A. R.; Hilgendorf, K. I.; Yang, A. V.; Kerr, J. P.; Hinken, A. C.; Demeter, J.; Kraft, P.; Mooney, N. A.; Yucel, N.; Jackson, P. K.; Blau, H. M.
10.1101/2020.03.20.000943 — cell biology — Posted on 2020-03-21
1384 The pathognomonic FOXL2 C134W mutation alters DNA binding specificity
Carles, A.; Trigo-Gonzalez, G.; Cao, R.; Cheng, S.- W. G.; Moksa, M.; Bilenky, M.; Morin, G. B.; Huntsman, D. G.; Hirst, M.
10.1101/2020.03.20.984476 — cancer biology — Posted on 2020-03-21
1385 Sulfopin, a selective covalent inhibitor of Pin1, blocks Myc-driven tumor initiation and growth in vivo
Dubiella, C.; Pinch, B. J.; Zaidman, D.; Manz, T. D.; Poon, E.; He, S.; Resnick, E.; Langer, E. M.; Daniel, C. J.; Seo, H.-S.; Chen, Y.; Ficarro, S. B.; Jamin, Y.; Lian, X.; Kibe, S.; Kozono, S.; Koikawa, K.; Doctor, Z. M.; Nabet, B.; Browne, C. M.; Yang, A.; Stoler-Barak, L.; Shah, R. B.; Vangos, N. E.; Geffken, E. A.; Oren, R.; Sidi, S.; Shulman, Z.; Wang, C.; Marto, J. A.; Dhe-Paganon, S.; Look, T.; Zhou, X. Z.; Lu, K. P.; Sears, R. C.; Chesler, L.; Gray, N. S.; London, N.
10.1101/2020.03.20.998443 — cancer biology — Posted on 2020-03-21
1387 Presynaptically silent synapses are modulated by the density of surrounding astrocytes
Oyabu, K.; Takeda, K.; Kawano, H.; Kubota, K.; Watanabe, T.; Harata, N. C.; Katsurabayashi, S.; Iwasaki, K.
10.1101/2020.03.20.000166 — neuroscience — Posted on 2020-03-21
1388 Insulin-Like Growth Factor I Modulates Sleep Through Hypothalamic Orexin Neurons
Zegarra-Valdivia, J. A.; Pignatelli, J.; Fernandez de Sevilla, E.; Fernandez, A. M.; Munive, V. A.; Martinez-Rachadell, L.; Nunez, A.; Torres Aleman, I.
10.1101/2020.03.20.000000 — neuroscience — Posted on 2020-03-21
1390 Mechanosensation Mediates Long-Range Spatial Decision-Making in an Aneural Organism
Murugan, N.; Kaltman, D.; Jin, H.; Chien, M.; Flores, R.; Nguyen, C.; Tuzoff, D.; Minabutdinov, A.; Kane, A.; Novak, R.; Ingber, D.; Levin, M.
10.1101/2020.03.20.985523 — animal behavior and cognition — Posted on 2020-03-21
1392 ZmCLA4 regulates leaf angle through multiple plant hormone-mediated signal pathways in maize
Chen, Y.; Dou, D.; Han, S.; Ku, L.; Liu, H.; Su, H.; Zhang, D.; Zeng, H.; Dong, Y.; Liu, Z.; Zhu, F.; Zhao, Q.; Xie, J.; Liu, Y.; Cheng, H.
10.1101/2020.03.20.999896 — molecular biology — Posted on 2020-03-21
1393 Impact of metastatic prostate cancer on human bone marrow
Baryawno, N.; Kfoury, Y.; Severe, N.; Mei, S.; Hirz, T.; Gustafsson, K. U.; Brouse, T.; Scadden, E.; Choi, B.; Barkas, N.; Shin, J.; Saylor, P.; Scadden, D.; Sykes, D.; Kharchenko, P.
10.1101/2020.03.19.998658 — cancer biology — Posted on 2020-03-21
1396 Evaluating institutional open access performance: Sensitivity analysis
Huang, C.-K.; Neylon, C.; Hosking, R.; Montgomery, L.; Wilson, K.; Ozaygen, A.; Brookes-Kenworthy, C.
10.1101/2020.03.19.998542 — scientific communication and education — Posted on 2020-03-21
1397 Evaluating institutional open access performance: Methodology, challenges and assessment
Huang, C.-K.; Neylon, C.; Hosking, R.; Montgomery, L.; Wilson, K.; Ozaygen, A.; Brookes-Kenworthy, C.
10.1101/2020.03.19.998336 — scientific communication and education — Posted on 2020-03-21
1398 Genomic Surveillance of Neisseria gonorrhoeae in the Philippines from 2013-2014
Villamin, A. S.; Argimon, S.; Jamoralin, M. C.; Boehme, K. D.; Masim, M. L.; Gayeta, J. M.; Lagrada, M. L.; Olorosa, A. M.; Cohen, V.; Hernandez, L. T.; Jeffrey, B.; Abudahab, K.; Hufano, C. M.; Sia, S. B.; Stelling, J.; Holden, M. T. G.; Aanensen, D. M.; Carlos, C. C.; on behalf of the Philippines Antimicrobial Resistance Surveillance Program,
10.1101/2020.03.19.998435 — genomics — Posted on 2020-03-21
1400 SSP: An R package to estimate sampling effort in studies of ecological communities
Guerra-Castro, E. J.; Cajas, J. C.; Dias Marques Simoes, F. N.; Cruz-Motta, J. J.; Mascaro, M.
10.1101/2020.03.19.996991 — ecology — Posted on 2020-03-21
1401 The Irish potato famine pathogen subverts host vesicle trafficking to channel starvation-induced autophagy to the pathogen interface
Pandey, P.; Leary, A. Y.; Tümtas, Y.; Savage, Z.; Dagvadorj, B.; Tan, E.; Khandare, V.; Duggan, C.; Yusunov, T.; Madalinski, M.; Gabriel Mirkin, F.; Schornack, S.; Dagdas, Y.; Kamoun, S.; Bozkurt, T. O.
10.1101/2020.03.20.000117 — plant biology — Posted on 2020-03-21
1403 Genomic Surveillance of Pseudomonas aeruginosa in the Philippines from 2013-2014
Chilam, J.; Argimon, S.; Limas, M. T.; Masim, M. L.; Gayeta, J. M.; Lagrada, M. L.; Olorosa, A. M.; Cohen, V.; Hernandez, L. T.; Jeffrey, B.; Abudahab, K.; Hufano, C.; Sia, S. B.; Holden, M. T. G.; Stelling, J.; Aanensen, D. M.; Carlos, C. C.; on behalf of the Philippines Antimicrobial Resistance Surveillance Program,
10.1101/2020.03.19.998229 — genomics — Posted on 2020-03-21
1404 Genomic Surveillance of Methicillin-Resistant Staphylococcus aureus in the Philippines from 2013-2014
Masim, M. M.; Argimon, S.; Espiritu, H. O.; Magbanua, M.; Lagrada, M. L.; Olorosa, A. M.; Cohen, V.; Gayeta, J. M.; Jeffrey, B.; Abudahab, K.; Hufano, C. M.; Sia, S. B.; Holden, M. T. G.; Stelling, J.; Aanensen, D. M.; Carlos, C. C.
10.1101/2020.03.19.998401 — genomics — Posted on 2020-03-21
1405 Conductance mechanisms of rapidly desensitizing cation channelrhodopsins from cryptophyte algae
Sineshchekov, O. A.; Govorunova, E. G.; li, H.; Wang, Y.; Melkonian, M.; Wong, G. K.-S.; Brown, L.; Spudich, J. L.
10.1101/2020.03.20.001099 — biochemistry — Posted on 2020-03-21
1407 The phylogenetic range of bacterial and viral pathogens of vertebrates
Shaw, L. P.; Wang, A. D.; Dylus, D.; Meier, M.; Pogacnik, G.; Dessimoz, C.; Balloux, F.
10.1101/670315 — ecology — Posted on 2020-03-21
1409 The structures of natively assembled clathrin coated vesicles
Paraan, M.; Mendez, J. H.; Sharum, S.; Kurtin, D.; He, H.; Stagg, S. M.
10.1101/2020.01.28.923128 — biophysics — Posted on 2020-03-21
1410 BNrich: A Bayesian network approach to the pathway enrichment analysis
Maleknia, S.; Sharifi-Zarchi, A.; Rezaei Tabar, V.; Namazi, M.; Kavousi, K.
10.1101/2020.01.13.905448 — bioinformatics — Posted on 2020-03-21
1411 Orbitofrontal control of visual cortex gain promotes visual associative learning
Liu, D.; Deng, J.; Zhang, Z.; Zhang, Z.-Y.; Sun, Y.-G.; Yang, T.; Yao, H.
10.1101/794958 — neuroscience — Posted on 2020-03-21
1413 K2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions
Lolicato, M.; Natale, A.; Aberemane-Ali, F.; Crottes, D.; Capponi, S.; Duman, R.; Wagner, A.; Rosenberg, J. M.; Grabe, M.; Minor, D. L.
10.1101/2020.03.20.000893 — biophysics — Posted on 2020-03-21
1414 The genetic structure of Norway
Mattingsdal, M.; Ebenesersdottir, S. S.; Moore, K. H. S.; Andreassen, O. A.; Hansen, T. F.; Werge, T.; Kockum, I.; Olsson, T.; Alfredsson, L.; Helgason, A.; Stefansson, K.; Hovig, E.
10.1101/2020.03.20.000299 — genetics — Posted on 2020-03-20
1418 The evolving systemic biomarker milieu in obese ZSF1 rat model of human cardiometabolic syndrome: Characterization of the model and cardioprotective effect of GDF15
Stolina, M.; Luo, X.; Dwyer, D.; Han, C.-Y.; Chen, R.; Zhang, Y.; Xiong, Y.; Chen, Y.; Yin, J.; Ason, B.; Hale, C.; Veniant, M. M.
10.1101/2020.03.20.000307 — physiology — Posted on 2020-03-20
1420 Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase
Chien, M.; Anderson, T. K.; Jockusch, S.; Tao, C.; Kumar, S.; Li, X.; Russo, J. J.; Kirchdoerfer, R.; Ju, J.
10.1101/2020.03.18.997585 — pharmacology and toxicology — Posted on 2020-03-20
1421 Identification of antiviral drug candidates against SARS-CoV-2 from FDA-approved drugs
Jeon, S.; Ko, M.; Lee, J.; Choi, I.; Byun, S. Y.; Park, S.; Shum, D.; Kim, S.
10.1101/2020.03.20.999730 — microbiology — Posted on 2020-03-20
1422 COMPOSITUM 1 (COM1) contributes to the architectural simplification of barley inflorescence via cell wall-mediated and meristem identity signals
Poursarebani, N.; Trautewig, C.; Melzer, M.; Nussbaumer, T.; Lundqvist, U.; Rutten, T.; Schmutzer, T.; Brandt, R.; Himmelbach, A.; Altschmied, L.; Koppolu, R.; Youssef, H. M.; Dalmais, M.; Bendahmane, A.; Stein, N.; Xin, Z.; Schnurbusch, T.
10.1101/2020.02.18.952705 — plant biology — Posted on 2020-03-20
1428 Loss of mu and delta opioid receptors on neurons expressing dopamine receptor D1 has no effect on reward sensitivity
Harda, Z.; Spyrka, J.; Jastrzebska, K.; Szumiec, L.; Bryksa, A.; Klimczak, M.; Polaszek, M.; Golda, S.; Zajdel, J.; Blasiak, A.; Rodriguez Parkitna, J. M.
10.1101/2020.03.18.996454 — neuroscience — Posted on 2020-03-20
1430 General DNA methylation patterns and environmentally-induced differential methylation in the eastern oyster (Crassostrea virginica)
Venkataraman, Y. R.; Downey-Wall, A.; Ries, J.; Westfield, I.; White, S. J.; Roberts, S.; Lotterhos, K. E.
10.1101/2020.01.07.897934 — genomics — Posted on 2020-03-20
1432 Mapping chromatin accessibility and active regulatory elements reveals new pathological mechanisms in human gliomas
Stepniak, K.; Machnicka, M. A.; Mieczkowski, J.; Macioszek, A.; Wojtas, B.; Gielniewski, B.; Krol, S. K.; Guzik, R.; Dabrowski, M. J.; Draminski, M.; Jardanowska, M.; Grabowicz, I.; Dziedzic, A.; Kranas, H.; Sienkiewicz, K.; Diamanti, K.; Kotulska, K.; Grajkowska, W.; Roszkowski, M.; Czernicki, T.; Marchel, A.; Komorowski, J.; Kaminska, B.; Wilczynski, B.
10.1101/867861 — cancer biology — Posted on 2020-03-20
1436 BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity
Bittner, Z. A.; Liu, X.; Dickhoefer, S.; Kalbacher, H.; Bosch, K.; Andreeva, L.; Shankar, S.; Marcu, A.; Shankar, S.; Stevanovic, S.; Mangan, M.; Duewell, P.; Lovotti, M.; Herster, F.; Loeffler, M. W.; Wolz, O. O.; Shilling, N. A.; Kuemmerle-Deschner, J.; Wagner, S.; Delor, A.; Grimbacher, B.; Wu, H.; Latz, E.; Weber, A. N.
10.1101/864702 — immunology — Posted on 2020-03-20
1437 BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity
Bittner, Z. A.; Liu, X.; Dickhoefer, S.; Kalbacher, H.; Bosch, K.; Andreeva, L.; Shankar, S.; Marcu, A.; Shankar, S.; Stevanovic, S.; Mangan, M.; Duewell, P.; Lovotti, M.; Herster, F.; Loeffler, M. W.; Wolz, O. O.; Shilling, N. A.; Kuemmerle-Deschner, J.; Wagner, S.; Delor, A.; Grimbacher, B.; Wu, H.; Latz, E.; Weber, A. N.
10.1101/864702 — immunology — Posted on 2020-03-20
1440 A mechanism to prevent transformation of the Whi3 mnemon into a prion.
Lau, Y.; Parfenova, I.; Saarikangas, J.; Nichols, R. A.; Barral, Y.; Caudron, F.
10.1101/2020.03.13.990119 — cell biology — Posted on 2020-03-20
1441 A mechanism to prevent transformation of the Whi3 mnemon into a prion.
Lau, Y.; Parfenova, I.; Saarikangas, J.; Nichols, R. A.; Barral, Y.; Caudron, F.
10.1101/2020.03.13.990119 — cell biology — Posted on 2020-03-20
1446 Actigraphy in brain-injured patients - A valid measurement for assessing circadian rhythms?
Angerer, M.; Schabus, M.; Raml, M.; Pichler, G.; Kunz, A. B.; Scarpatetti, M.; Trinka, E.; Blume, C.
10.1101/839472 — neuroscience — Posted on 2020-03-20
1450 Ancient MAPK ERK7 is regulated by an unusual inhibitory scaffold required for Toxoplasma apical complex biogenesis
Back, P. S.; O'Shaughnessy, W. J.; Moon, A. S.; Dewangan, P. S.; Wohlschlegel, J. L.; Sha, J.; Bradley, P.; Reese, M. L.
10.1101/2020.02.02.931089 — microbiology — Posted on 2020-03-20
1451 Virulence potential of a multidrug-resistant Escherichia coli strain belonging to the emerging clonal group ST101-B1 isolated from bloodstream infection
Gheller, A. C. d. M. S.; Silva, R. M.; Valiatti, T. B.; Santos-Neto, J. F.; Santos, F. F.; Cayo, R.; Streling, A. P.; Nodari, C. S.; Gales, A. C.; Nishiyama-Junior, M. Y.; Carvalho, E.; Gomes, T. A. T.
10.1101/797928 — microbiology — Posted on 2020-03-20
1452 A molecular cell atlas of the human lung from single cell RNA sequencing
Travaglini, K. J.; Nabhan, A. N.; Penland, L.; Sinha, R.; Gillich, A.; Sit, R. V.; Chang, S.; Conley, S. D.; Mori, Y.; Seita, J.; Berry, G. J.; Shrager, J. B.; Metzger, R. J.; Kuo, C. S.; Neff, N.; Weissman, I. L.; Quake, S. R.; Krasnow, M. A.
10.1101/742320 — genomics — Posted on 2020-03-20
1455 CryoSIM: super resolution 3D structured illumination cryogenic fluorescence microscopy for correlated ultra-structural imaging
Phillips, M. A.; Harkiolaki, M.; Pinto, D. M. S.; Parton, R. M.; Palanca, A.; Garcia-Moreno, M.; Kounatidis, I.; Sedat, J.; Stuart, D. I.; Castello, A.; Booth, M. J.; Davis, I.; Dobbie, I. M.
10.1101/2020.03.09.980334 — cell biology — Posted on 2020-03-20
1456 Secreted autotaxin through LPA suppresses chemotaxis and tumor infiltration of CD8+ T cells
Matas-Rico, E.; van der Haar Avila, I.; van Zon, M.; Morris, A. J.; Koster, J.; Salgado-Polo, F.; de Kivit, S.; de Rink, I.; Lanca, T.; Alba, J. M.; Johnson, Z.; Farrow, S.; Haanen, J.; Schumacher, T. N.; Perrakis, A.; Borst, J.; Verbrugge, I.; van den Berg, J.; Moolenaar, W. H.
10.1101/2020.02.26.966291 — cancer biology — Posted on 2020-03-20
1457 PICRUSt2: An improved and customizable approach for metagenome inference
Douglas, G. M.; Maffei, V. J.; Zaneveld, J.; Yurgel, S. N.; Brown, J. R.; Taylor, C. M.; Huttenhower, C.; Langille, M. G. I.
10.1101/672295 — bioinformatics — Posted on 2020-03-20
1459 Distinct metabolic states of a cell guide alternate fates of mutational buffering through altered proteostasis
Verma, K.; Saxena, K.; Donaka, R.; Chaphalkar, A.; Rai, M. K.; Shukla, A.; Zaidi, Z.; Dandage, R.; Shanmugam, D.; Chakraborty, K.
10.1101/540039 — biochemistry — Posted on 2020-03-20
1461 Sequential combinations of chemotherapeutic agents with BH3 mimetics to treat rhabdomyosarcoma and avoid resistance.
Alcon, C.; Manzano-Munoz, A.; Prada, E.; Mora, J.; Soriano, A.; Guillen, G.; Gallego, S.; Roma, J.; Samitier, J.; Villanueva, A.; Montero, J.
10.1101/2020.01.24.918532 — cancer biology — Posted on 2020-03-20
1466 MiR-146a controls age related bone loss
Saferding, V.; Hofmann, M.; Brunner, J. S.; Niederreiter, B.; Timmen, M.; Magilnick, N.; Hayer, S.; Heller, G.; Steiner, G.; Stange, R.; Boldin, M.; Schabbauer, G.; Weigl, M.; Hackl, M.; Grillari, J.; Smolen, J. S.; Blueml, S.
10.1101/2020.03.20.000174 — molecular biology — Posted on 2020-03-20
1467 The molecular structure of primary cilia revealed by cryo-electron tomography
Kiesel, P.; Alvarez Viar, G.; Tsoy, N.; Maraspini, R.; Honigmann, A.; Pigino, G.
10.1101/2020.03.20.000505 — molecular biology — Posted on 2020-03-20
1468 Accurate Identification of SARS-CoV-2 from Viral Genome Sequences using Deep Learning
Lopez-Rincon, A.; Tonda, A.; Mendoza-Maldonado, L.; Claassen, E.; Garssen, J.; Kraneveld, A. D.
10.1101/2020.03.13.990242 — bioinformatics — Posted on 2020-03-20
1469 The BBSome assembly is spatially controlled by BBS1 and BBS4 in human cells
Prasai, A.; Schmidt Cernohorska, M.; Ruppova, K.; Niederlova, V.; Andelova, M.; Draber, P.; Stepanek, O.; Huranova, M.
10.1101/2020.03.20.000091 — cell biology — Posted on 2020-03-20
1470 SGK1 Signaling Promotes Glucose Metabolism and Survival in Extracellular Matrix Detached Cells
Mason, J. A.; Cockfield, J. A.; Pape, D. J.; Meissner, H.; Sokolowski, M.; White, T. C.; Valentin Lopez, J. C.; Liu, J.; Liu, X.; Martinez-Reyes, I.; Chandel, N. S.; Locasale, J. W.; Schafer, Z. T.
10.1101/2020.03.20.000463 — cell biology — Posted on 2020-03-20
1471 IDH1 Mutations Induce Organelle Defects Via Dysregulated Phospholipids
Larion, M.; Lita, A.; Pliss, A.; Kuzmin, A.; Yamasaki, T.; Zhang, L.; Dowdy, T.; Burks, C.; de Val, N.; Celiku, O.; Ruiz-Rodado, V.; Nicoli, E.-R.; Kruhlak, M.; Andresson, T.; Das, S.; Yang, C.; Schmitt, R.; Herold-Mende, C.; Gilbert, M. R.; Prasad, P. N.
10.1101/2020.03.20.000414 — cancer biology — Posted on 2020-03-20
1472 Motor neurons involved in fine motor control are labeled by tracing Atoh1-lineage neurons in the spinal cord
Ogujiofor, O. W.; Pop, I. V.; Espinosa, F.; Durodoye, R. O.; Viacheslavov, M. L.; Jarvis, R.; Landy, M. A.; Fishell, G.; Machold, R. P.; Lai, H. C.
10.1101/2020.03.20.000588 — developmental biology — Posted on 2020-03-20
1474 Mutational synergy coordinately remodels chromatin accessibility, enhancer landscape and 3-Dimensional DNA topology to alter gene expression during leukemia induction
Yun, H.; Vohra, S.; Mupo, A.; Giotopoulos, G.; Sasca, D.; Horton, S. J.; Agrawal-Singh, S.; Meduri, E.; Basheer, F.; Marando, L.; Gozdecka, M.; Dovey, O. M.; Castillo-Venzor, A.; Wang, X.; Gallipoli, P.; Mueller-Tidow, C.; Osborne, C. S.; Vassiliou, G. S.; Huntly, B. J. P.
10.1101/2020.03.20.000059 — cancer biology — Posted on 2020-03-20
1475 An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 and multiple endemic, epidemic and bat coronavirus
Sheahan, T. P.; Sims, A. C.; Zhou, S.; Hill, C.; Leist, S. R.; Schaefer, A.; Agostini, M.; Pruijssers, A.; Brown, A. J.; Bluemling, G.; Natchus, M.; Saindane, M.; Kolykhalov, A.; Painter, G.; Swanstrom, R.; Dinnon, K.; Graham, R.; Harcourt, J.; Tamin, A.; Thornburg, N. J.; Montgomery, S. A.; Chappell, J.; Denison, M.; Baric, R. S.
10.1101/2020.03.19.997890 — microbiology — Posted on 2020-03-20
1476 The first-in-class peptide binder to the SARS-CoV-2 spike protein
Zhang, G.; Pomplun, S.; Loftis, A. R.; Loas, A.; Pentelute, B. L.
10.1101/2020.03.19.999318 — bioengineering — Posted on 2020-03-20
1477 ZeroCostDL4Mic: an open platform to simplify access and use of Deep-Learning in Microscopy
Chamier, L. v.; Jukkala, J.; Spahn, C.; Lerche, M.; Hernandez-perez, S.; Mattila, P.; Karinou, E.; Holden, S.; Can Solak, A.; Krull, A.; Buchholz, T.-O.; Jug, F.; Royer, L. A.; Heilemann, M.; Laine, R. F.; Jacquemet, G.; Henriques, R.
10.1101/2020.03.20.000133 — bioinformatics — Posted on 2020-03-20
1484 Ammonia-based enrichment and long-term propagation of zone I hepatocyte-like cells
Tsuneishi, R.; Saku, N.; Miyata, S.; Javaregowda, P. K.; Ite, K.; Toyoda, M.; Kimura, T.; Kuroda, M.; Nakazawa, A.; Kasahara, M.; Nonaka, H.; Kamiya, A.; Kiyono, T.; Yamauchi, J.; Umezawa, A.
10.1101/2020.03.20.999680 — cell biology — Posted on 2020-03-20
1488 Gaze-evoked deformations of the optic nerve head in thyroid eye disease
Fisher, L. K.; Wang, X.; Tun, T. A.; Chung, H.-W.; Milea, D.; Girard, M. J. A.
10.1101/2020.03.19.999706 — bioengineering — Posted on 2020-03-20
1489 AMPAR trafficking dependent LTP initiates cortical remapping and adaptive behaviors during sensory experience
Campelo, T.; Augusto, E.; Chenouard, N.; de Miranda, A.; Kouskoff, V.; Choquet, D.; Gambino, F.
10.1101/2020.03.19.999094 — neuroscience — Posted on 2020-03-20
1490 mRNA decapping machinery targets LBD3/ASL9 transcripts to authorize developmental reprogramming in Arabidopsis
Zuo, Z.; Roux, M. E.; Chevalier, J. R.; Dagdas, Y.; Yamashino, T.; hojgaard, s. d.; knight, e.; Ostergaard, L.; Petersen, M.
10.1101/834465 — plant biology — Posted on 2020-03-20
1491 Acarbose Protects From Central and Peripheral Metabolic Imbalance Induced by Benzene Exposure
Debarba, L. K.; Mulka, A.; Lima, J. B. M. d.; Didyuk, O.; Fakhoury, P.; Koshko, L.; Awada, A. A.; Zhang, K.; Klueh, U.; Sadagurski, M.
10.1101/2020.03.19.998567 — physiology — Posted on 2020-03-20
1493 HIV-1 Vpr-induced Proinflammatory Response and Apoptosis are Mediated through the Sur1-Trpm4 Channel in Astrocytes
Li, G.; Makar, T. K.; Gerzanich, V.; Kalakonda, S.; Ivanova, S.; Pereira, E. F. R.; Simard, J. M.; ZHAO, R. Y.
10.1101/2020.03.19.999268 — neuroscience — Posted on 2020-03-20
1494 Conversion of marginal land into switchgrass conditionally accrues soil carbon and reduces methane consumption
Bates, C. T.; Escalas, A.; Kuang, J.; Hale, L.; Wang, Y.; Herman, D.; Nuccio, E. E.; Wang, X.; Fu, Y.; Tian, R.; Wang, G.; Ning, D.; Yang, Y.; Wu, L.; Pett-Ridge, J.; Saha, M.; Craven, K.; Firestone, M. K.; Zhou, J.
10.1101/2020.03.18.997304 — molecular biology — Posted on 2020-03-20
1497 Host shifting and host sharing in a genus of specialist flies diversifying alongside their sunflower hosts
Hippee, A. C.; Beer, M. A.; Bagley, R. K.; Condon, M. A.; Kitchen, A.; Lisowski, E. A.; Norrbom, A. L.; Forbes, A. A.
10.1101/2020.03.18.995589 — evolutionary biology — Posted on 2020-03-20
1498 Intraspecific difference among herbivore lineages and their host-plant specialization drive the strength of trophic cascades
Sentis, A.; Bertram, R.; Dardenne, N.; Simon, J.-C.; Magro, A.; Pujol, B.; Danchin, E.; Hemptinne, J.-L.
10.1101/722140 — ecology — Posted on 2020-03-20
1499 Excessive E2F transcription in single cancer cells precludes transient cell cycle exit after DNA damage.
Segeren, H. S.; van Rijnberk, L. M.; Moreno, E.; Riemers, F. M.; Yuan, R.; Wubbolts, R.; de Bruin, A.; Westendorp, B.
10.1101/2020.03.19.998674 — cancer biology — Posted on 2020-03-20
1502 Improving the accessibility and transferability of machine learning algorithms for identification of animals in camera trap images: MLWIC2
Tabak, M. A.; Norouzzadeh, M. S.; Wolfson, D. W.; Newton, E. J.; Boughton, R. K.; Ivan, J. S.; Odell, E. A.; Newkirk, E. S.; Conrey, R. Y.; Stenglein, J.; Iannarilli, F.; Erb, J.; Brook, R. K.; Davis, A. J.; Lewis, J.; Walsh, D. P.; Beasley, J. C.; VerCauteren, K. C.; Clune, J.; Miller, R. S.
10.1101/2020.03.18.997700 — ecology — Posted on 2020-03-20
1504 Active Listening
Friston, K.; Sajid, N.; Quiroga-Martinez, D. R.; Parr, T.; Price, C. J.; Holmes, E.
10.1101/2020.03.18.997122 — neuroscience — Posted on 2020-03-20
1508 Selective antibiofilm properties and biocompatibility of nano-ZnO and nano-ZnO/Ag coated surfaces
Rosenberg, M.; Visnapuu, M.; Vija, H.; Kisand, V.; Kasemets, K.; Kahru, A.; Ivask, A.
10.1101/2020.03.18.996967 — microbiology — Posted on 2020-03-20
1509 Long read assembly of the pandemic strain of Austropuccinia psidii (myrtle rust) reveals an unusually large (gigabase sized) and repetitive fungal genome.
Tobias, P. A.; Schwessinger, B.; Deng, C. H.; Wu, C.; Dong, C. M.; Sperschneider, J.; Jones, A.; Smith, G. R.; Tibbits, J.; Chagne, D.; Park, R.
10.1101/2020.03.18.996108 — genomics — Posted on 2020-03-20
1510 An inverted Caveolin-1 topology defines a novel exosome secreted from prostate cancer cells
Ariotti, N.; Wu, Y.; Okano, S.; Gambin, Y.; Follett, J.; Rae, J.; Ferguson, C.; Teasdale, R. D.; Alexandrov, K.; Meunier, F. A.; Hill, M. M.; Parton, R. G.
10.1101/2020.03.19.999441 — cell biology — Posted on 2020-03-20
1512 Orally Bioavailable Endochin-like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts
Doggett, J. S.; Schultz, T. L.; Miller, A.; Bruzual, I.; Pou, S.; Winter, R. W.; Dodean, R.; Zakharov, L. N.; Nilsen, A.; Riscoe, M. K.; Carruthers, V. B.
10.1101/2020.03.19.999664 — pharmacology and toxicology — Posted on 2020-03-20
1513 The homeoprotein ENGRAILED-1 promotes motoneuron survival and motor functions
Vargas Abonce, S. E.; Leboeuf, M.; Moya, K. L.; Prochiantz, A. L.
10.1101/734020 — neuroscience — Posted on 2020-03-20
1514 Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity
Cui, L.; Chen, S.-Y.; Lerbs, T.; Lee, J.-W.; Domizi, P.; Gordon, S.; Kim, Y.-h.; Nolan, G. P.; Betancur, P.; Wernig, G.
10.1101/2020.03.18.997080 — immunology — Posted on 2020-03-20
1519 On the ecology and distribution of steelhead (Oncorhynchus mykiss) in California's Eel River
Kannry, S. H.; Thompson, S. A.; O'Rourke, S. M.; Harris, S. L.; Kelson, S. J.; Miller, M. R.
10.1101/2020.03.18.996934 — ecology — Posted on 2020-03-20
1521 CMTM6 drives cisplatin resistance in OSCC by regulating AKT mediated Wnt signaling
Mohapatra, P.; Shriwas, O.; Mohanty, S.; Kaushik, S. R.; Arya, R.; Rath, R.; Das Majumdar, S.; Muduly, D.; Nanda, R. K.; Dash, R.
10.1101/2020.03.18.993774 — cancer biology — Posted on 2020-03-20
1522 Cellular mRNA signals in human kidney tumors
Young, M. D.; Mitchell, T. J.; Custers, L. M.; Khabirova, E.; Oliver, T. R.; Comitani, F.; Piapi, A.; Blanco, E. B.; Thevanesan, C.; Roberts, K.; Braga, F. A. V.; Coorens, T. H.; Valle, I. D.; Wilbrey-Clark, A.; Mamanova, L.; Stewart, G. D.; Gnanapragasam, V. J.; Rampling, D.; Sebire, N.; Coleman, N.; Hook, L.; Warren, A.; Haniffa, M.; Kool, M.; Pfister, S. M.; Achermann, J. C.; He, X.; Barker, R. A.; Shlien, A.; Bayraktar, O. A.; Teichmann, S.; Meyer, K. B.; Drost, J.; Straathof, K.; Behjati, S.
10.1101/2020.03.19.998815 — cancer biology — Posted on 2020-03-20
1523 Maintenance of epithelial traits and resistance to mesenchymal reprogramming promote proliferation in metastatic breast cancer
Eichelberger, L.; Saini, M.; Moreno, H. D.; Klein, C.; Bartsch, J. M.; Falcone, M.; Reitberger, M.; Espinet, E.; Vogel, V.; Graf, E.; Schwarzmayr, T.; Strom, T.-M.; Lehmann, M.; Koenigshoff, M.; Pfarr, N.; Wuerth, R.; Donato, E.; Haas, S.; Spaich, S.; Suetterlin, M.; Schneeweiss, A.; Weichert, W.; Schotta, G.; Trumpp, A.; Sprick, M. R.; Scheel, C. H.
10.1101/2020.03.19.998823 — cancer biology — Posted on 2020-03-20
1524 Fast quantitative analysis of timsTOF PASEF data with MSFragger and IonQuant
Yu, F.; Haynes, S. E.; Teo, G. C.; Avtonomov, D. M.; Polasky, D. A.; Nesvizhskii, A. I.
10.1101/2020.03.19.999334 — bioinformatics — Posted on 2020-03-20
1525 Lab-on-a-graphene-FET detection of key molecular events underpinning influenza virus infection and effect of antiviral drugs
Ono, T.; Kamada, K.; Hayashi, R.; Piacenti, A. R.; Gabutt, C.; Sriwilaijaroen, N.; Hiramatsu, H.; Kanai, Y.; Inoue, K.; Nakakita, S.-i.; Kawahara, T.; Ie, Y.; Watanabe, Y.; Suzuki, Y.; Contera, S.; Matsumoto, K.
10.1101/2020.03.18.996884 — bioengineering — Posted on 2020-03-20
1527 Thioproline formation as a driver of formaldehyde toxicity in Escherichia coli
Patterson, J. A.; He, H.; Folz, J. S.; Lee, Q.; Wilson, M. A.; Fiehn, O.; Bruner, S. D.; Bar-Even, A.; Hanson, A. D.
10.1101/2020.03.19.981027 — biochemistry — Posted on 2020-03-20
1533 Fine-mapping and QTL tissue-sharing information improve causal gene identification and transcriptome prediction performance
Barbeira, A. N.; Liang, Y.; Bonazzola, R.; Wang, G.; Wheeler, H. E.; Melia, O. J.; Aguet, F.; The GTEx Consortium, ; Ardlie, K. G.; Wen, X.; Im, H. K.
10.1101/2020.03.19.997213 — genomics — Posted on 2020-03-20
1538 Lamin A redistribution mediated by nuclear deformation determines dynamic localization of YAP
Koushki, N.; Ghagre, A.; Kishore Srivastava, L.; Sitaras, C.; Yoshie, H.; Molter, C.; Ehrlicher, A.
10.1101/2020.03.19.998708 — biophysics — Posted on 2020-03-20
1539 In Silico Investigations on Curcuminoids from Curcuma longa as Positive Regulators of Wnt/β-catenin Signaling Pathway in Wound Healing
Reshad, R. A. I.; Alam, S.; Raihan, H. B.; Meem, K. N.; Rahman, F.; Zahid, F.; Rafid, M. I.; Rahman, S. M. O.; Ali, M. H.
10.1101/2020.03.19.998286 — bioinformatics — Posted on 2020-03-20
1540 parSMURF, a High Performance Computing tool for the genome-wide detection of pathogenic variants
Petrini, A.; Mesiti, M.; Schubach, M.; Frasca, M.; Danis, D.; Re, M.; Grossi, G.; Cappelletti, L.; Castrignano', T.; Robinson, P. N.; Valentini, G.
10.1101/2020.03.18.994079 — bioinformatics — Posted on 2020-03-20
1541 A Sec14-like Phosphatidylinositol Transfer Protein Paralog Defines a Novel Class of Heme-binding Proteins With An Unusual Heme Coordination Mechanism
Khan, D.; Lee, D.; Gulten, G.; Aggarwal, A.; Wofford, J.; Inna, K. V.; Tripathi, A.; Patrick, J. W.; Eckert, D. M.; Laganowsky, A.; Sacchettini, J. C.; Lindahl, P.; Bankaitis, V.
10.1101/2020.03.19.999003 — biochemistry — Posted on 2020-03-20
1545 Identification of an antiretroviral small molecule that appears to be a host-targeting inhibitor of HIV-1 assembly
Reed, J. C.; Solas, D.; Kitaygorodskyy, A.; Freeman, B.; Ressler, D. T. B.; Phuong, D. J.; Swain, J. V.; Lingappa, V. R.; Lingappa, J. R.
10.1101/2020.03.18.998088 — microbiology — Posted on 2020-03-20
1546 Computational vaccinology based development of multi-epitope subunit vaccine for protection against the Norovirus infections
Ahmad, I.; Ali, S. S.; Shah, I.; Khan, S.; Khan, M.; Ullah, S.; Ali, S.; Khan, J.; Ali, M.; Khan, A.; Wei, D.-Q.
10.1101/2020.03.18.997197 — immunology — Posted on 2020-03-20
1547 CitrusKB: A Comprehensive Knowledge Base for Transcriptome and Interactome of Citrus spp. Infected by Xanthomonas citri subsp. citri at Different Infection Stages
Ferrasa, A.; Murata, M. M.; Cofre, T. D. C. G.; Cavallini, J. S.; Peron, G.; Juliao, M. H. M.; Belasque, J.; Ferreira, H.; Ferro, M. I. T.; Leite, R. P.; Penha, H.; Carvalho, F. M. S.; Varani, A. M. H.; Herai, R. H.; Ferro, J. A.
10.1101/2020.03.19.997999 — genomics — Posted on 2020-03-20
1549 Transcriptional mediators of treatment resistance in lethal prostate cancer
He, M. X.; Cuoco, M. S.; Crowdis, J.; Bosma-Moody, A.; Zhang, Z.; Bi, K.; Kanodia, A.; Su, M.-J.; Rodman, C.; DelloStritto, L.; Shah, P.; Burke, K. P.; Izar, B.; Bakouny, Z.; Tewari, A. K.; Liu, D.; Camp, S. Y.; Vokes, N. I.; Park, J.; Vigneau, S.; Fong, L.; Rozenblatt-Rosen, O.; Regev, A.; Rotem, A.; Taplin, M.-E.; Van Allen, E. M.
10.1101/2020.03.19.998450 — genomics — Posted on 2020-03-20
1550 Regulatory Sharing Between Estrogen Receptor α Bound Enhancers
Carleton, J. B.; Ginley-Hidinger, M.; Berrett, K. C.; Layer, R. M.; Quinlan, A. R.; Gertz, J.
10.1101/2020.03.18.997403 — genetics — Posted on 2020-03-20
1551 Genetics of recombination rate variation in the pig
Johnsson, M.; Whalen, A.; Ros-Freixedes, R.; Gorjanc, G.; Chen, C.-Y.; Herring, W. O.; de Koning, D.-J.; Hickey, J. M.
10.1101/2020.03.17.995969 — genetics — Posted on 2020-03-20
1556 Evolution of an enzyme conformational ensemble guides design of an efficient biocatalyst
Broom, A.; Rakotoharisoa, R. V.; Thompson, M. C.; Zarifi, N.; Nguyen, E.; Mukhametzhanov, N.; Liu, L.; Fraser, J. S.; Chica, R. A.
10.1101/2020.03.19.999235 — biophysics — Posted on 2020-03-20
1558 OrganoidTracker: efficient cell tracking using machine learning and manual error correction
Kok, R. N. U.; Hebert, L.; Huelsz-Prince, G.; Goos, Y. J.; Zheng, X.; Bozek, K.; Stephens, G. J.; Tans, S. J.; van Zon, J. S.
10.1101/2020.03.18.996421 — bioinformatics — Posted on 2020-03-20
1560 Click-ExM enables expansion microscopy for all biomolecules
Sun, D.-e.; Fan, X.; Zhang, H.; Huang, Z.; Tang, Q.; Li, W.; Bai, J.; Lei, X.; Chen, X.
10.1101/2020.03.19.998039 — bioengineering — Posted on 2020-03-20
1561 Traceback of Core Transcription Factors for Soybean Root Growth Maintenance under Water Deficit
Lin, L.; De Velde, J.; Nguyen, N.; Meyer, R.; An, Y.-Q.; Song, L.; Valliyodan, B.; Prince, S.; Wan, J.; Murphy, M. C.; Kim, E.; Lee, I.; Pentecost, G.; Zhu, C.; Kushwaha, G.; Joshi, T.; Chen, W.; Patil, G.; Mutava, R.; Xu, D.; Vandepoele, K.; Nguyen, H. T.
10.1101/2020.03.19.999482 — plant biology — Posted on 2020-03-20
1563 SPHERE: A novel approach to 3D and active sound localization
Gaveau, v.; Coudert, A.; Salemme, R.; Koun, E.; Desoche, C.; Truy, E.; Farne, A.; Pavani, F.
10.1101/2020.03.19.998906 — neuroscience — Posted on 2020-03-20
1565 Revisiting the Association between Human Leukocyte Antigen and End-Stage Renal Disease
Noureen, N.; Shah, F. A.; Lisec, J.; Usman, H.; Khalid, M.; Munir, R.; Zaidi, N.
10.1101/2020.03.18.996330 — molecular biology — Posted on 2020-03-20
1566 DONSON and FANCM associate with different replisomes distinguished by replication timing and chromatin domain
Zhang, J.; Bellani, M. A.; James, R. C.; Pokharel, D.; Zhang, Y.; Reynolds, J. J.; McNee, G. S.; Jackson, A. P.; Stewart, G. S.; Seidman, M. M.
10.1101/2020.03.19.999102 — molecular biology — Posted on 2020-03-20
1571 CD56 regulates human NK cell cytotoxicity through Pyk2
Gunesch, J.; Dixon, A. L.; Ebrahim, T.; Berrien-Elliott, M.; Tatineni, S.; Kumar, T.; Solloa, E. H.; Fehniger, T. A.; Mace, E.
10.1101/2020.03.19.998427 — immunology — Posted on 2020-03-20
1572 Dynamin-related Irgm proteins modulate LPS-induced caspase-4 activation and septic shock
Finethy, R.; Dockterman, J.; Kutsch, M.; Orench-Rivera, N.; Wallace, G.; Piro, A.; Luoma, S.; Haldar, A.; Hwang, S.; Martinez, J.; Kuehn, M.; Taylor, G.; Coers, J.
10.1101/2020.03.18.997460 — immunology — Posted on 2020-03-20
1573 The histone variant H2A.W promotes heterochromatin accessibility for efficient DNA methylation in Arabidopsis
Bourguet, P.; Picard, C. L.; Yelagandula, R.; Pelissier, T.; Lorkovic, Z. J.; Pouch-Pelissier, M.-N.; Jacobsen, S. E.; Berger, F.; Mathieu, O.
10.1101/2020.03.19.998609 — genomics — Posted on 2020-03-20
1574 Population sequencing enhances understanding of tea plant evolution
Wang, X.; Feng, H.; Chang, Y.; Ma, C.; Wang, L.; Hao, X.; Li, A.; Cheng, H.; Wang, L.; Cui, P.; Jin, J.; Wang, X.; Wei, K.; Ai, C.; Wu, Z.; Zhao, S.; Li, Y.; Liu, B.; Wang, G.; Chen, L.; Ruan, J.; Yang, Y.
10.1101/2020.03.19.998393 — genomics — Posted on 2020-03-20
1576 Transcriptome-wide profiles of circular RNA and RNA binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression
Okholm, T. L. H.; Sathe, S.; Park, S. S.; Kamstrup, A. B.; Rasmussen, A. M.; Shankar, A.; Fristrup, N.; Nielsen, M. M.; Vang, S.; Dyrskjoet, L.; Aigner, S.; Damgaard, C. K.; Yeo, G.; Pedersen, J. S.
10.1101/2020.03.19.997478 — genomics — Posted on 2020-03-20
1578 Chromosomal resolution reveals symbiotic virus colonization of parasitic wasp genomes
Gauthier, J.; Boulain, H.; van Vugt, J. J. F. A.; Baudry, L.; Persyn, E.; Aury, J.-M.; Noel, B.; Bretaudeau, A.; Legeai, F.; Warris, S.; Chebbi, M. A.; Dubreuil, G.; Duvic, B.; Kremer, N.; Gayral, P.; Musset, K.; Josse, T.; Bigot, D.; Bressac, C.; Moreau, S.; Periquet, G.; Harry, M.; Montagne, N.; Boulogne, I.; Sabeti-Azad, M.; Maibeche, M.; Chertemps, T.; Hilliou, F.; Siaussat, D.; Amselem, J.; Luyten, I.; Capdevielle-Dulac, C.; Labadie, K.; Lais Merlin, B.; Barbe, V.; de Boer, J. G.; Marbouty, M.; Luis Consoli, F.; Dupas, S.; Hua Van, A.; Le Goff, G.; Bezier, A.; Jacquin-Joly, E.; Whitfield,
10.1101/2020.03.19.994459 — genomics — Posted on 2020-03-20
1582 Exercise promotes satellite cell contribution to myofibers in a load-dependent manner
Masschelein, E.; D'Hulst, G.; Zvick, J.; Hinte, L. C.; Soro-Arnaiz, I.; Gorski, T.; von Meyenn, F.; Bar-Nur, O.; De Bock, K.
10.1101/2020.03.19.998211 — cell biology — Posted on 2020-03-20
1583 Critical role for cold shock protein YB-1 in cytokinesis
Mehta, S.; Algie, M.; Al-Jabri, T.; McKinney, C.; Kannan, S.; Verma, C. S.; Ma, W.; Zhang, J.; Bartolec, T. K.; Masamsetti, V. P.; Parker, K.; Henderson, L.; Gould, M.; Bhatia, P.; Harfoot, R.; Chircop, M.; Kleffmann, T.; Cohen, S.; Woolley, A.; Cesare, A. J.; Braithwaite, A.
10.1101/2020.03.18.997817 — cell biology — Posted on 2020-03-20
1586 EFA6B regulates a stop signal for collective invasion in breast cancer
Fayad, R.; Vazquez Rojas, M.; Partisani, M.; Finetti, P.; Dib, S.; Virolle, V.; Cabaud, O.; Lopez, M.; Birnbaum, D.; Bertucci, F.; Franco, M.; Luton, F.
10.1101/2020.03.19.998575 — cancer biology — Posted on 2020-03-20
1589 Intracellular Delivery of Nanoparticles via Microelectrophoresis Technique: Feasibility demonstration
Han, M.; Zhao, J.; Fabian, J. M.; Mustafa, S.; Ruan, Y.; Wiederman, S.; Ebendorff-Heidepriem, H.
10.1101/2020.03.18.996173 — biochemistry — Posted on 2020-03-20
1591 Hormonal regulation of the BRC1-dependent strigolactone transcriptome involved in shoot branching responses
Kerr, S. C.; de Saint Germain, A.; Dissanayake, I. M.; Mason, M. G.; Dun, E. A.; Tanurdzic, M.; Beveridge, C. A.
10.1101/2020.03.19.999581 — plant biology — Posted on 2020-03-20
1594 Fidgetin-like 2 is a novel negative regulator of axonal growth and can be targeted to promote functional nerve regeneration after injury.
Baker, L. A.; Tar, M.; Villegas, G.; Charafeddine, R.; Kramer, A.; Vafaeva, O.; Nacharaju, P.; Friedman, J.; Davies, K.; Sharp, D.
10.1101/2020.03.19.999508 — neuroscience — Posted on 2020-03-20
1595 Neuron Type-Specific Translatomes in Spinal Cords of Naive and Neuropathic Mice
Das Gupta, R. R.; Scheurer, L.; Pelczar, P.; Ralvenius", W.; Wildner, H.; Zeilhofer, H. U.
10.1101/2020.03.19.996645 — neuroscience — Posted on 2020-03-20
1598 Revealing 29 sets of independently modulated genes in Staphylococcus aureus, their regulators and role in key physiological responses
Poudel, S.; Tsunemoto, H.; Seif, Y.; Sastry, A. V.; Szubin, R.; Xu, S.; Machado, H.; Olson, C.; Anand, A.; Pogliano, J.; Nizet, V.; Palsson, B.
10.1101/2020.03.18.997296 — microbiology — Posted on 2020-03-20
1604 PacBio SMRT-based full-length transcriptome data of Ascosphaera apis mycelium and spore
Du, Y.; Wang, J.; Chen, H.; Fan, X.; Zhu, Z.; Fan, Y.; Jiang, H.; Xiong, C.; Zhen, Y.; Chen, D.; Guo, R.
10.1101/2020.03.19.998625 — evolutionary biology — Posted on 2020-03-20
1607 Genomics of sex allocation in the parasitoid wasp Nasonia vitripennis
Pannebakker, B. A.; Cook, N.; van den Heuvel, J.; van de Zande, L.; Shuker, D. M.
10.1101/2020.03.18.997619 — evolutionary biology — Posted on 2020-03-20
1609 Single-cell transcriptome profiling an adult human cell atlas of 15 major organs
He, S.; Wang, L.; Liu, Y.; Li, Y.; Chen, H.; Xu, J.; Peng, W.; Lin, G.; Wei, P.; Li, B.; Xia, X.; Wang, D.; BEI, J.-X.; He, X.; Guo, Z.
10.1101/2020.03.18.996975 — cell biology — Posted on 2020-03-20
1611 Automated design and optimization of multitarget schizophrenia drug candidates by deep learning
Tan, X.; Jiang, X.; He, Y.; Zhong, F.; Li, X.; Xiong, Z.; Li, Z.; Liu, X.; Chen, C.; Zhao, Q.; Xie, Y.; Yang, F.; Wu, C.; Shen, J.; Wang, Z.; Jiang, H.; Zheng, M.
10.1101/2020.03.19.999615 — bioinformatics — Posted on 2020-03-20
1612 Convergent evolution of the Hedgehog/Intein fold in protein splicing
Beyer, H. M.; Virtanen, S. I.; Aranko, A. S.; Mikula, K. M.; Lountos, G. T.; Wlodawer, A.; Ollila, O. H. S.; Iwai, H.
10.1101/2020.03.19.998260 — biochemistry — Posted on 2020-03-20
1617 Anchoring the human olfactory system to a functional gradient
Waymel, A.; Friedrich, P.; Bastian, P.-A.; Forkel, S.; Thiebaut de Schotten, M.
10.1101/2020.03.19.998849 — neuroscience — Posted on 2020-03-20
1618 Mouth magnetoencephalography: A unique perspective on the human hippocampus
Tierney, T. M.; Levy, A.; Barry, D. N.; Meyer, S. S.; Shigihara, Y.; Everatt, M.; Mellor, S.; Lopez, J. D.; Bestmann, S.; Holmes, N.; Roberts, G.; Hill, R. M.; Boto, E.; Leggett, J.; Shah, V.; Brookes, M. J.; Bowtell, R.; Maguire, E. A.; Barnes, G. R.
10.1101/2020.03.19.998641 — neuroscience — Posted on 2020-03-20
1620 α-Synuclein strains that cause distinct pathologies differentially inhibit proteasome
Suzuki, G.; Imura, S.; Hosokawa, M.; Katsumata, R.; Nonaka, T.; Hisanaga, S.-I.; Saeki, Y.; Hasegawa, M.
10.1101/2020.03.19.999086 — neuroscience — Posted on 2020-03-20
1623 A Novel Small Animal Model of Norovirus Diarrhea
Roth, A. N.; Helm, E. W.; Mirabelli, C.; Kirsche, E.; Smith, J.; Eurell, L. B.; Ghosh, S.; Altan-Bonnet, N.; Wobus, C. E.; Karst, S. M.
10.1101/2020.03.19.999185 — microbiology — Posted on 2020-03-20
1624 From iron to antibiotics: Identification of conserved bacterial-fungal interactions across diverse partners
Pierce, E. C.; Morin, M.; Little, J. C.; Liu, R. B.; Tannous, J.; Keller, N. P.; Wolfe, B. E.; Sanchez, L. M.; Dutton, R. J.
10.1101/2020.03.19.999193 — microbiology — Posted on 2020-03-20
1625 CDK8 fine-tunes IL-6 transcriptional activities by limiting STAT3 resident time at the gene loci
Martinez-Fabregas, J.; Wang, L.; Pohler, E.; Cozzani, A.; Kazemian, M.; Mitra, S.; Moraga, I.
10.1101/2020.03.19.998351 — immunology — Posted on 2020-03-20
1629 p53 plays a central role in lymphatic anomalies
Mylavarapu, R.; Kulikauskas, M.; Dierkes, C.; Finlon, J.; Sobhani, N.; Stevens, W.; Mangette, M.; Arbab, F.; Box, N. F.; Muley, A.; Shawber, C.; Lovell, M.; Kiefer, F.; Tamburini, B.; Terzian, T.
10.1101/2020.03.18.992784 — developmental biology — Posted on 2020-03-20
1630 Functional analysis of the chromosomal passenger complex in Arabidopsis
Komaki, S.; Takeuchi, H.; Hamamura, Y.; Heese, M.; Hashimoto, T.; Schnittger, A.
10.1101/2020.03.19.998880 — cell biology — Posted on 2020-03-20
1631 Htr6 and Sstr3 ciliary targeting relies on both IC3 loops and C-terminal tails
Barbeito, P.; Tachibana, Y.; Martin-Morales, R.; Moreno, P.; Mykytyn, K.; Kobayashi, T.; Garcia-Gonzalo, F. R.
10.1101/2020.03.19.997262 — cell biology — Posted on 2020-03-20
1633 RRBP1 rewires cisplatin resistance in Oral Squamous Cell Carcinoma by regulating YAP-1
Shriwas, O.; Arya, R.; Mohanty, S.; Kumar, S.; Rath, R.; Kaushik, S. R.; Thakur, M. C.; Pahwa, F.; Majumdar, S. K. D.; Muduly, D. K.; Nanda, R.; Dash, R.
10.1101/2020.03.18.998070 — cancer biology — Posted on 2020-03-20
1635 Molecular Basis of Host-Adaptation Interactions between Influenza Virus Polymerase PB2 Subunit and ANP32A
Zarco, A. C.; Kalayil, S.; Maurin, D.; Salvi, N.; Delaforge, E.; Milles, S.; Jensen, M. R.; Hart, D. J.; Cusack, S.; Blackledge, M.
10.1101/2020.03.18.996579 — biophysics — Posted on 2020-03-20
1637 A Graphic User Interface (GUI) to build a 3D printed personalized Prosthetic Hand
Lazaro, J. M.; Garrido de Lazaro, K. M.; Sujumnong, N.; Miscione, J.; Wee, A.; gondokaryono, r.
10.1101/2020.03.18.997486 — bioengineering — Posted on 2020-03-20
1638 Dodecin as carrier protein for immunizations and bioengineering applications
Bourdeaux, F.; Kopp, Y.; Lautenschlaeger, J.; Goessner, I.; Besir, H.; Vabulas, R. M.; Grininger, M.
10.1101/2020.03.19.990861 — bioengineering — Posted on 2020-03-20
1641 YASS: Yet Another Spike Sorter applied to large-scale multi-electrode array recordings in primate retina
Lee, J.; Mitelut, C.; Shokri, H.; Kinsella, I.; Dethe, N.; Wu, S.; Li, K.; Reyes, E. B.; Turcu, D.; Batty, E.; Kim, Y. J.; Brackbill, N.; Kling, A.; Goetz, G.; Chichilnisky, E. J.; Carlson, D.; Paninski, L.
10.1101/2020.03.18.997924 — neuroscience — Posted on 2020-03-20
1647 BK polyomavirus evades innate immune sensing by disrupting the mitochondrial network and membrane potential and promotes mitophagy
Manzetti, J.; Weissbach, F. H.; Graf, F. E.; Unterstab, G.; Wernli, M.; Hopfer, H.; Drachenberg, C. B.; Rinaldo, C. H.; Hirsch, H. H.
10.1101/2020.03.19.994988 — microbiology — Posted on 2020-03-20
1648 Start codon disruption with CRISPR/Cas9 prevents murine Fuchs' endothelial corneal dystrophy
Uehara, H.; Zhang, X.; Pereira, F.; Narendran, S.; Choi, S.; Bhuvanagiri, S.; Liu, J.; Ravi Kumar, S.; Bohner, A.; Carroll, L.; Archer, B.; Zhang, Y.; Liu, W.; Gao, G.; Ambati, J.; Jun, A. S.; Ambati, B. K.
10.1101/2020.03.18.996728 — genomics — Posted on 2020-03-20
1649 The microRNA, miR-133b, functions to slow Duchenne muscular dystrophy pathogenesis
Taetzsch, T.; Shapiro, D.; Eldosougi, R.; Myers, T.; Settlage, R.; Valdez, G.
10.1101/2020.03.19.988519 — cell biology — Posted on 2020-03-20
1651 Global analysis of adenylate-forming enzymes reveals β-lactone biosynthesis pathway in pathogenic Nocardia
Robinson, S. L.; Terlouw, B. R.; Smith, M. D.; Pidot, S. J.; Stinear, T. P.; Medema, M. H.; Wackett, L. P.
10.1101/856955 — biochemistry — Posted on 2020-03-19
1653 Blunted Diurnal Firing in Lateral Habenula Projections to Dorsal Raphe Nucleus and Delayed Photoentrainment in Stress-Susceptible Mice.
Liu, H.; Rastogi, A.; Sabanovic, M.; Alhammadi, A. D.; Xu, Q.; Guo, L.; Cao, J.-L.; Zhang, H.; Narain, P.; Aqel, H.; Mlambo, V.; Rezgui, R.; Radwan, B.; Chaudhury, D.
10.1101/2020.03.19.998732 — neuroscience — Posted on 2020-03-19
1660 Single cell chromatin accessibility of the developmental cephalochordate
Chen, D.; Xu, X.; Huang, Z.; Ding, X.; Xu, Z.; Zhong, J.; Liang, L.; Xu, L.; Chai, C.; Wang, H.; Qiu, J.; Zhu, J.; wang, x.; Xiang, R.; Wu, W.; Ding, P.; Wang, F.; Feng, Q.; Zhou, S.; Yuan, Y.; Wu, W.; Yan, Y.; Zhou, Y.; Chen, D.; Li, G.; Zhu, S.; Chen, F.; Zhang, Q.; Wu, J.
10.1101/2020.03.17.994954 — developmental biology — Posted on 2020-03-19
1662 Repurposing cell growth-regulating compounds identifies kenpaullone which ameliorates pathologic pain via normalization of inhibitory neurotransmission
Yeo, M.; Chen, Y.; Jiang, C.; Chen, G.; Wang, K.; Bortsov, A.; Lioudino, M.; Zeng, Q.; Wang, Z.; Busciglio, J.; Ji, R.-R.; Liedtke, W.
10.1101/767681 — neuroscience — Posted on 2020-03-19
1663 TMAO, a seafood-derived molecule, produces diuresis and reduces mortality in heart failure rats
Gawrys-Kopczynska, M.; Konop, M.; Maksymiuk, K.; Kraszewska, K.; Derzsi, L.; Sozanski, K.; Holyst, R.; Pilz, M.; Samborowska, E.; Dobrowolski, L.; Jaworska, K.; Mogilnicka, I.; Ufnal, M.
10.1101/2020.03.18.986869 — physiology — Posted on 2020-03-19
1664 Profiling microglia from AD donors and non-demented elderly in acute human post-mortem cortical tissue
Alsema, A. M.; Jiang, Q.; Kracht, L.; Gerrits, E.; Dubbelaar, M. L.; Miedema, A.; Brouwer, N.; Woodbury, M.; Wachter, A.; Xi, H. S.; Moeller, T.; Biber, K. P.; Kooistra, S. M.; Boddeke, E. H. W. G. M.; Eggen, B. J. L.
10.1101/2020.03.18.995332 — neuroscience — Posted on 2020-03-19
1665 CHOmics: a web-based tool for multi-omics data analysis and interactive visualization in CHO cell lines
Lin, D.; Yalamanchili, H.; Zhang, X.; Lewis, N. E.; Alves, C. S.; Groot, J.; Arnsdorf, J.; Peterson Bjorn, S.; Wulff, T.; Rude Voldborg, B. G.; Zhou, Y.; Zhang, B.
10.1101/2020.03.17.995290 — bioinformatics — Posted on 2020-03-19
1666 Comparing quality of reporting between preprints and peer-reviewed articles in the biomedical literature
Carneiro, C. F. D.; Queiroz, V. G. S.; Moulin, T. C.; Carvalho, C. A. M.; Haas, C. B.; Rayee, D.; Henshall, D. E.; De-Souza, E. A.; Amorim, F. E.; Boos, F. Z.; Guercio, G. D.; Costa, I. R.; Hajdu, K. L.; van Egmond, L.; Modrak, M.; Tan, P. B.; Abdill, R. J.; Burgess, S. J.; Guerra, S. F. S.; Bortoluzzi, V. T.; Amaral, O. B.
10.1101/581892 — scientific communication and education — Posted on 2020-03-19
1669 Diet-induced loss of adipose Hexokinase 2 triggers hyperglycemia
Shimobayashi, M.; Shetty, S.; Frei, I. C.; Wölnerhanssen, B. K.; Weissenberger, D.; Dietz, N.; Thomas, A.; Ritz, D.; Meyer-Gerspach, A. C.; Maier, T.; Hay, N.; Peterli, R.; Rohner, N.; Hall, M. N.
10.1101/2019.12.28.887794 — physiology — Posted on 2020-03-19
1670 Towards the molecular architecture of the peroxisomal receptor docking complex
Lill, P.; Hansen, T.; Wendscheck, D.; Klink, B. U.; Jeziorek, T.; Miehling, J.; Bender, J.; Drepper, F.; Girzalsky, W.; Erdmann, R.; Warscheid, B.; Gatsogiannis, C.
10.1101/854497 — molecular biology — Posted on 2020-03-19
1671 Interrupting reactivation of immunological memory reprograms allergy and averts anaphylaxis
Bruton, K.; Spill, P.; Vohra, S.; Baribeau, O.; Manzoor, S.; Gadkar, S.; Davidson, M.; Walker, T. D.; Ellenbogen, Y.; Florescu, A.; Wen, J.; Chu, D. K.; Waserman, S.; Jimenez-Saiz, R.; Epelman, S.; Robbins, C.; Jordana, M.
10.1101/2020.03.04.975706 — immunology — Posted on 2020-03-19
1673 A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress
Stephani, M.; Picchianti, L.; Gajic, A.; Beveridge, R.; Skarwan, E.; Sanchez de Medina Hernandez, V.; Mohseni, A.; Clavel, M.; Zeng, Y.; Naumann, C.; Matuszkiewicz, M.; Turco, E.; Loefke, C.; Li, B.; Durnberger, G.; Schutzbier, M.; Chen, H. T.; Abdrakhmanov, A.; Savova, A.; Chia, K.-S.; Djamei, A.; Schaffner, I.; Abel, S.; Jiang, L.; Mechtler, K.; Ikeda, F.; Martens, S.; Clausen, T.; Dagdas, Y.
10.1101/2020.03.18.995316 — cell biology — Posted on 2020-03-19
1676 Automatic Detection of Synaptic Partners in a Whole-Brain Drosophila EM Dataset
Buhmann, J.; Sheridan, A.; Gerhard, S.; Krause, R.; Nguyen, T.; Heinrich, L.; Schlegel, P.; Lee, W.-C. A.; Wilson, R.; Saalfeld, S.; Jefferis, G. S. X. E.; Bock, D.; Turaga, S.; Cook, M.; Funke, J.
10.1101/2019.12.12.874172 — neuroscience — Posted on 2020-03-19
1679 See and Sequence: Integrating Whole-Genome Sequencing Within the National Antimicrobial Resistance Surveillance Program in the Philippines
Argimon, S.; Masim, M. A. L.; Gayeta, J. M.; Lagrada, M. L.; Macaranas, P. K. V.; Cohen, V.; Limas, M. T.; Espiritu, H. O.; Palarca, J. C.; Chilam, J.; Jamoralin, M. C.; Alfred, A. S.; Borlasa, J. B.; Olorosa, A. M.; Hernandez, L. F. T.; Boehme, K. D.; Jeffrey, B.; Abudahab, K.; Hufano, C. M.; Sia, S. B.; Stelling, J.; Holden, M. T. G.; Aanensen, D. M.; Carlos, C. C.; the Antimicrobial Resistance Surveillance Program,
10.1101/808378 — genomics — Posted on 2020-03-19
1680 Body weight at young adulthood and association with epigenetic aging and lifespan in the BXD murine family
Sandoval-Sierra, J. V.; Helbing, A. H.; Williams, E. G.; Ashbrook, D. G.; Roy, S.; Williams, R. W.; Mozhui, K.
10.1101/791582 — genomics — Posted on 2020-03-19
1682 Concurrence of Porin Loss and Modular Amplification of β-Lactamase Encoding Genes Drives Carbapenem Resistance in a Cohort of Recurrent Enterobacterales Bacteremia
Shropshire, W. C.; Aitken, S. L.; Pifer, R.; Kim, J.; Bhatti, M. M.; Li, X.; Kalia, A.; Galloway-Pena, J.; Sahasrabhojane, P.; Arias, C. A.; Greenberg, D. E.; Hanson, B. M.; Shelburne, S.
10.1101/616961 — genomics — Posted on 2020-03-19
1683 LC/MS-QToF Profiling, Anti-Diabetic and Anti-Adipogenic potential of Divya MadhuKalp: A Novel Herbo-mineral Formulation
Balkrishna, A.; Joshi, A.; Das, S. K.; Bisht, L.; Sakat, S.; Sharma, V.; Sharma, N.; Joshi, K.; Verma, S.; Sharma, V. K.; Joshi, C. S.
10.1101/2020.02.15.950865 — cell biology — Posted on 2020-03-19
1685 Understanding the role of urban design in disease spreading
Brizuela, N. G.; Garcia-Chan, N.; Gutierrez Pulido, H.; Chowell, G.
10.1101/766667 — systems biology — Posted on 2020-03-19
1686 Rhythms of Transcription in Field-Grown Sugarcane Are Highly Organ Specific
Dantas, L. L. B.; Almeida-Jesus, F. M.; de Lima, N. O.; Alves-Lima, C.; Nishiyama, M. Y.; Carneiro, M. S.; Souza, G. M.; Hotta, C. T.
10.1101/607002 — plant biology — Posted on 2020-03-19
1688 Is Oculudentavis a bird or even archosaur?
Li, Z.; Wang, W.; Hu, H.; Wang, M.; Yi, H.; Lu, J.
10.1101/2020.03.16.993949 — paleontology — Posted on 2020-03-19
1691 Cellular internalization of Godanti Bhasma (anhydrous CaSO4) induces massive cytoplasmic reversible vacuolation and survival response of mammalian cells.
Balkrishna, A.; Das, S. K.; Joshi, A.; Sharma, V.; Bisht, L.; Das, N.; Sharma, N.; Shukla, S.; Mehra, D.; Joshi, K.; Dhara, S.
10.1101/2020.02.01.930594 — cell biology — Posted on 2020-03-19
1693 Modeling Cell-Specific Dynamics and Regulation of the Common Gamma Chain Cytokines
Farhat, A. M.; Weiner, A. C.; Posner, C.; Kim, Z. S.; Orcutt-Jahns, B.; Carlson, S. M.; Meyer, A. S.
10.1101/778894 — immunology — Posted on 2020-03-19
1694 Mutant screen for reproduction unveils depression-associated Piccolo's control over reproductive behavior
A. Medrano, G.; Singh, M.; J. Plautz, E.; B. Good, L.; M. Chapman, K.; Chaudhary, J.; Jaichander, P.; M. Powell, H.; Pudasaini, A.; M. Shelton, J.; A. Richardson, J.; Xie, X.-J.; Ivics, Z.; Braun, C.; Ackermann, F.; C. Garner, C.; Izsvak, Z.; Hamra, F. K.
10.1101/405985 — genetics — Posted on 2020-03-19
1696 Multiple approaches for massively parallel sequencing of HCoV-19 (SARS-CoV-2) genomes directly from clinical samples
Xiao, M.; Liu, X.; Ji, J.; Li, M.; Li, J.; Yang, L.; Sun, W.; Ren, P.; Yang, G.; Zhao, J.; Liang, T.; Ren, H.; Chen, T.; Zhong, H.; Song, W.; Wang, Y.; Deng, Z.; Zhao, Y.; Ou, Z.; Wang, D.; Cai, J.; Cheng, X.; Feng, T.; Wu, H.; Gong, Y.; Yang, H.; Wang, J.; Xu, X.; Zhu, S.; Chen, F.; Zhang, Y.; Chen, W.; Li, Y.; Li, J.
10.1101/2020.03.16.993584 — genomics — Posted on 2020-03-19
1697 The giant sequoia genome and proliferation of disease resistance genes
Scott, A. D.; Zimin, A.; Puiu, D.; Workman, R.; Britton, M.; Zaman, S.; Caballero, M.; Read, A. C.; Bogdanove, A. J.; Burns, E.; Wegrzyn, J. L.; Timp, W.; Salzberg, S. L.; Neale, D. B.
10.1101/2020.03.17.995944 — genomics — Posted on 2020-03-19
1698 Single-cell transcriptomic analysis of the adult mouse spinal cord
Blum, J.; Klemm, S.; Nakayama, L.; Kathiria, A.; Guttenplan, K.; Hoang, P.; Shadrach, J.; Kaltschmidt, J.; Greenleaf, W.; Gitler, A. D.
10.1101/2020.03.16.992958 — neuroscience — Posted on 2020-03-19
1701 Enhancer and Promoter Usage in the Normal and Failed Human Heart
Gacita, A. M.; Dellefave-Castillo, L.; Page, P. G. T.; Barefield, D. Y.; Wasserstrom, A.; Puckelwartz, M. J.; Nobrega, M. A.; McNally, E. M.
10.1101/2020.03.17.988790 — genomics — Posted on 2020-03-19
1703 Molecular Typing of Human Respiratory Adenoviruses with Universal PCR and Sequencing Primers for Three Major Capsid Genes: Penton base, Hexon, and Fiber
Zhang, J.; Sridhar, S.; Lau, S. K. P.; Liu, J.; Ou, J.; Yan, Y.; Zhao, S.; Lan, W.; Guan, W.; Wu, J.; Woo, P. C. Y.; Seto, D.; Zhang, Q.
10.1101/2020.03.17.995373 — microbiology — Posted on 2020-03-19
1705 Dispersal ability of Neophilaenus campestris, a vector of Xylella fastidiosa, from olive groves to over-summering hosts
Clara, L.; Morente, M.; De las Heras-Bravo, D.; Marti-Campoy, A.; Rodriguez-Ballester, F.; Plaza, M.; Moreno, A.; FERERES, A.
10.1101/2020.03.17.995266 — ecology — Posted on 2020-03-19
1708 ODELAM: Rapid sequence-independent detection of drug resistance in clinical isolates of Mycobacterium tuberculosis
Herricks, T.; Donczew, M.; Mast, F.; Rustad, T.; Morrison, R.; Sterling, T. R.; Sherman, D.; Aitchison, J. D.
10.1101/2020.03.17.995480 — microbiology — Posted on 2020-03-19
1709 Membrane-Interactive Compounds from Pistacia lentiscus L. Thwart Pseudomonas aeruginosa Virulence
Tahrioui, A.; Ortiz, S.; Azuama, O. C.; Bouffartigues, E.; Benalia, N.; Tortuel, D.; Maillot, O.; Chemat, S.; Kritsanida, M.; Feuilloley, M.; Orange, N.; Michel, S.; Lesouhaitier, O.; Cornelis, P.; Grougnet, R.; Boutefnouchet, S.; Chevalier, S.
10.1101/2020.03.17.995043 — microbiology — Posted on 2020-03-19
1710 Changes in group size during resource shifts reveal drivers of sociality across the tree of life
Kao, A. B.; Hund, A. K.; Santos, F. P.; Young, J.-G.; Bhat, D.; Garland, J.; Oomen, R. A.; McCreery, H. F.
10.1101/2020.03.17.994343 — animal behavior and cognition — Posted on 2020-03-19
1712 YAP and TAZ promote periosteal osteoblast precursor expansion and differentiation for fracture repair
Kegelman, C. D.; Nijsure, M. P.; Moharrer, Y.; Pearson, H. B.; Dawahare, J. H.; Jordan, K. M.; Qin, L.; Boerckel, J. D.
10.1101/2020.03.17.995761 — developmental biology — Posted on 2020-03-19
1713 Codon bias determines sorting of ion channel protein
Thiel, G.; Kithil, M.; Engel, A. J.; Langhans, M.; Rauh, O.; Cartolano, M.; Van Etten, J. L.; Moroni, A.
10.1101/2020.03.17.994780 — cell biology — Posted on 2020-03-19
1714 CYCA3;4 Is a Post-Prophase Target of the APC/CCCS52A2 E3 Ligase Controlling Formative Cell Divisions in Arabidopsis
Willems, A.; Heyman, J.; Eekhout, T.; Achon, I.; Garcia, J. P.; Zhu, T.; Li, L.; Vercauteren, I.; Van den Daele, H.; van de Cotte, B.; De Smet, I.; De Veylder, L.
10.1101/2020.03.17.995506 — plant biology — Posted on 2020-03-19
1718 Genome sequences of both organelles of the grapevine rootstock cultivar 'Börner'
Frommer, B.; Holtgräwe, D. L.; Hausmann, L.; Viehöver, P.; Hüttel, B.; Töpfer, R.; Weisshaar, B.
10.1101/2020.03.18.996405 — plant biology — Posted on 2020-03-19
1721 HiCanu: accurate assembly of segmental duplications, satellites, and allelic variants from high-fidelity long reads
Nurk, S.; Walenz, B. P.; Rhie, A.; Vollger, M. R.; Logsdon, G. A.; Grothe, R.; Miga, K. H.; Eichler, E. E.; Phillippy, A. M.; Koren, S.
10.1101/2020.03.14.992248 — bioinformatics — Posted on 2020-03-19
1722 Chamaeleo: a robust library for DNA storage coding schemes
Ping, Z.; Zhang, H.; Chen, S.; Zhuang, Q.; Zhu, S.; Shen, Y.
10.1101/2020.01.02.892588 — bioinformatics — Posted on 2020-03-19
1724 White matter microstructure in attention-deficit/hyperactivity disorder: a systematic tractography study in 654 individuals
Damatac, C. G.; Zwiers, M.; Chauvin, R. J. M.; van Rooij, D.; Akkermans, S. E. A.; Naaijen, J.; Hoekstra, P. J.; Hartman, C. A.; Oosterlaan, J.; Franke, B.; Buitelaar, J. K.; Beckmann, C. F.; Sprooten, E.
10.1101/787713 — neuroscience — Posted on 2020-03-19
1726 Genetic variation and sex differences are missed opportunities for addiction biology.
Saul, M. C.; Bagley, J. R.; Bailey, L. S.; Datta, U.; Dickson, P. E.; Dodd, R.; Gagnon, L. H.; Kimble, V. M.; Leonardo, M.; Kim, S.-M.; Olson, A.; Roy, T.; Schoenrock, S. E.; Wilcox, T.; Jentsch, J. D.; Logan, R. W.; McClung, C. A.; Philip, V. M.; Reinholdt, L. G.; Rizzo, S. J. S.; Tarantino, L. M.; Chesler, E. J.
10.1101/2020.02.14.949784 — neuroscience — Posted on 2020-03-19
1727 Toward a unified connectomic target for deep brain stimulation in obsessive-compulsive disorder
Li, N.; Baldermann, J. C.; Kibleur, A.; Treu, S.; Akram, H.; Elias, G. J. B.; Boutet, A.; Lozano, A. M.; Al-Fatly, B.; Strange, B.; Barcia, J.; Zrinzo, L.; Joyce, E.; Chabardes, S.; Visser-Vandewalle, V.; Polosan, M.; Kuhn, J.; Kühn, A. A.; Horn, A.
10.1101/608786 — neuroscience — Posted on 2020-03-19
1728 Structure of population activity in primary motor cortex for single finger flexion and extension
Arbuckle, S. A.; Weiler, J.; Kirk, E. A.; Rice, C. L.; Schieber, M. H.; Pruszynski, J. A.; Ejaz, N.; Diedrichsen, J.
10.1101/2020.03.17.996124 — neuroscience — Posted on 2020-03-19
1730 Autism-linked gene FoxP1 selectively regulates the cultural transmission of learned vocalizations
Garcia-Oscos, F.; Koch, T.; Pancholi, H.; Trusel, M.; Daliparthi, V.; Ayhan, F.; Co, M.; Alam, D. H.; Holdway, J. E.; Konopka, G.; Roberts, T. F.
10.1101/2020.03.14.992016 — neuroscience — Posted on 2020-03-19
1731 Asparagine signals mitochondrial respiration and can be targeted to impair tumour growth
Krall, A. S.; Mullen, P. J.; Surjono, F.; Momcilovic, M.; Schmid, E. W.; Halbrook, C. J.; Thambundit, A.; Mittelman, S. D.; Lyssiotis, C. A.; Shackelford, D. B.; Knott, S. R.; Christofk, H. R.
10.1101/2020.03.17.995670 — cancer biology — Posted on 2020-03-19
1732 ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer
Shi, X.; Yokom, A. L.; Wang, C.; Young, L. N.; Youle, R. J.; Hurley, J. H.
10.1101/840009 — biochemistry — Posted on 2020-03-19
1733 From the roundabout of molecular events to nanomaterial-induced chronic inflammation prediction
Majaron, H.; Kokot, B.; Sebastijanovic, A.; Voss, C.; Podlipec, R.; Zawilska, P.; Berthing, T.; Ballester Lopez, C.; Danielsen, P. H.; Contini, C.; Ivanov, M.; Kriselj, A.; Cotar, P.; Zhou, Q.; Ponti, J.; Zhernovkov, V.; Schneemilch, M.; Manel Doumandji, Z.; Pusnik, M.; Umek, P.; Pajk, S.; Joubert, O.; Schmid, O.; Urbancic, I.; Irmler, M.; Beckers, J.; Lobaskin, V.; Halappanavar, S.; Quirke, N.; Lyubartsev, A.; Vogel, U.; Koklic, T.; Stoeger, T.; Strancar, J.
10.1101/2020.02.27.966036 — molecular biology — Posted on 2020-03-19
1734 Chromosight: A computer vision program for pattern detection in chromosome contact maps
Matthey-Doret, C.; Baudry, L.; Breuer, A.; Guiglielmoni, N.; Moreau, P.; Vigouroux, A.; Montagne, R.; Scolari, V.; Politis, L.; Meot, A.; Oriol, E.; Chanut, P.-H.; Campeas, A.; Jean, E.; Koszul, R.; Cournac, A.
10.1101/2020.03.08.981910 — bioinformatics — Posted on 2020-03-19
1735 Screening of FDA-approved drugs using a MERS-CoV clinical isolate from South Korea identifies potential therapeutic options for COVID-19
Ko, M.; Chang, S. Y.; Byun, S. Y.; Choi, I.; d'Alexandry d'Orengiani, A. L. P. H.; Shum, D.; Min, J.-Y.; Windisch, M. P.
10.1101/2020.02.25.965582 — microbiology — Posted on 2020-03-19
1737 High sensitivity detection of coronavirus SARS-CoV-2 using multiplex PCR and a multiplex-PCR-based metagenomic method
Li, C.; Debruyne, D. N.; Spencer, J.; Kapoor, V.; Liu, L. Y.; Zhou, B.; Lee, L.; Feigelman, R.; Burdon, G.; Liu, J.; Oliva, A.; Borcherding, A.; Tan, H.; Urban, A. E.; Liu, G.; Liu, Z.
10.1101/2020.03.12.988246 — genomics — Posted on 2020-03-19
1738 Prochlorococcus phage ferredoxin: structural characterization and interactions with cyanobacterial sulfite reductases
Campbell, I. J.; Olmos, J. L.; Xu, W.; Kahanda, D.; Atkinson, J. T.; Sparks, O. N.; Miller, M. D.; Phillips, G. N.; Bennett, G. N.; Silberg, J. J.
10.1101/2020.02.07.937771 — biochemistry — Posted on 2020-03-19
1740 Is Oculudentavis a bird or even archosaur?
Li, Z.; Wang, W.; Hu, H.; Wang, M.; Yi, H.; Lu, J.
10.1101/2020.03.16.993949 — paleontology — Posted on 2020-03-19
1743 Comparative population genetic structure of two Ixodidae ticks (Ixodes ovatus and Haemaphysalis flava) in Niigata Prefecture, Japan
Regilme, M. A. F.; Sato, M.; Tamura, T.; Arai, R.; Sato, M. O.; Ikeda, S.; Doi, M.; Tanaka, K.; Gamboa, M.; Monaghan, M. T.; Watanabe, K.
10.1101/862904 — genetics — Posted on 2020-03-19
1745 Midbody remnant inheritance is regulated by the ESCRT subunit CHMP4C
Casares Arias, J.; Gonzalez, M. U.; San Paulo, A.; Ventimiglia, L. N.; Sadler, J. B.; Miguez, D. G.; Labat-de-Hoz, L.; Rubio-Ramos, A.; Rangel, L.; Bernabe-Rubio, M.; Fernandez-Barrera, J.; Correas, I.; Martin-Serrano, J.; Alonso, M. A.
10.1101/810523 — cell biology — Posted on 2020-03-19
1749 Interpretable Machine Learning for Perturbation Biology
Yuan, B.; Shen, C.; Luna, A.; Korkut, A.; Marks, D.; Ingraham, J.; Sander, C.
10.1101/746842 — systems biology — Posted on 2020-03-19
1750 Orchard layout and plant traits influence fruit yield more strongly than pollinator behaviour and density in a dioecious crop
Peace, A.; Pattermore, D.; Broussard, M.; Fonseka, D.; Tomer, N.; Bosque-Perez, N. A.; Crowder, D.; Shaw, A. K.; Jesson, L.; Howlett, B.; Jochym, M.; Li, J.
10.1101/2020.03.18.996736 — plant biology — Posted on 2020-03-18
1754 Disentangling presentation and processing times in the brain
Caplette, L.; Ince, R. A. A.; Jerbi, K.; Gosselin, F.
10.1101/566042 — neuroscience — Posted on 2020-03-19
1755 Multivariate phenotypic divergence along an urbanization gradient
Santangelo, J. S.; Advenard, C.; Rivkin, L. R.; Thompson, K. A.
10.1101/699017 — evolutionary biology — Posted on 2020-03-19
1759 Data-driven detection of subtype-specific and differentially expressed genes
Chen, L.; Lu, Y.; Yu, G.; Clarke, R.; Van Eyk, J.; Herrington, D.; Wang, Y.
10.1101/517961 — bioinformatics — Posted on 2020-03-19
1761 Erosion of human X chromosome inactivation alters proteome expression from genes across the X chromosome and all autosomes
Brenes, A. J.; Yoshikawa, H.; Bensaddek, D.; Mirauta, B.; Seaton, D. D.; Hukelmann, J. L.; Jiang, H.; Stegle, O.; Lamond, A. I.
10.1101/2020.03.18.997049 — biochemistry — Posted on 2020-03-19
1762 Generation of neuronal diversity from common progenitors via Notch signaling in the cerebellum
Zhang, T.; Liu, T.; Mora, N.; Guegan, J.; Bertrand, M.; Contreras, X.; Hansen, A.; Streicher, C.; Anderle, M.; Tiberi, L.; Hippenmeyer, S.; Hassan, B. A.
10.1101/2020.03.18.997205 — developmental biology — Posted on 2020-03-19
1763 Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling
Fenech, E. J.; Lari, F.; Charles, P. D.; Fischer, R.; Laetitia-Thezenas, M.; Bagola, K.; Paton, A. W.; Paton, J. C.; Gyrd-Hansen, M.; Kessler, B. M.; Christianson, J. C.
10.1101/2020.03.18.993998 — cell biology — Posted on 2020-03-19
1764 A Novel Machine Learning Approach Uncovers New and Distinctive Inhibitors for Cyclin-Dependent Kinase 9
Assmann, M.; Bal, M.; Craig, M.; D'Oyley, J.; Phillips, L.; Triendl, H.; Bates, P. A.; Bashir, U.; Ruprah, P.; Shaker, N.; Stojevic, V.
10.1101/2020.03.18.996538 — bioinformatics — Posted on 2020-03-19
1766 Identifying dynamic protein and RNA proximity interaction networks of actinin reveals RNA-binding and metabolic regulatory mechanisms
Ladha, F. A.; Thakar, K.; Pettinato, A. M.; Legere, N.; Cohn, R.; Romano, R.; Meredith, E.; Chen, Y.-s.; Hinson, J. T.
10.1101/2020.03.18.994004 — cell biology — Posted on 2020-03-19
1767 A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress
Stephani, M.; Picchianti, L.; Gajic, A.; Beveridge, R.; Skarwan, E.; Sanchez de Medina Hernandez, V.; Mohseni, A.; Clavel, M.; Zeng, Y.; Naumann, C.; Matuszkiewicz, M.; Turco, E.; Loefke, C.; Li, B.; Durnberger, G.; Schutzbier, M.; Chen, H. T.; Abdrakhmanov, A.; Savova, A.; Chia, K.-S.; Djamei, A.; Schaffner, I.; Abel, S.; Jiang, L.; Mechtler, K.; Ikeda, F.; Martens, S.; Clausen, T.; Dagdas, Y.
10.1101/2020.03.18.995316 — cell biology — Posted on 2020-03-19
1768 Accurate 4Pi single-molecule localization using an experimental PSF model
Li, Y.; Buglakova, E.; Zhang, Y.; Thevathasan, J. V.; Bewersdorf, J.; Ries, J.
10.1101/2020.03.18.997163 — biophysics — Posted on 2020-03-19
1770 Non-Toxic Virucidal Macromolecules Show High Efficacy Against Influenza Virus Ex Vivo and In Vivo
Kocabiyik, O.; Cagno, V.; Sedano, L.; Bhide, Y.; Mettier, J.; Medaglia, C.; Da Costa, B.; Zhu, Y.; Constant, S.; Huang, S.; Kaiser, L.; Hinrichs, W.; Huckriede, A.; Le Goffic, R.; Tapparel, C.; Stellacci, F.
10.1101/2020.03.18.996678 — microbiology — Posted on 2020-03-18
1771 Plasmidome analysis of carbapenem-resistant Enterobacteriaceae isolated in Vietnam
Hirabayashi, A.; Yahara, K.; Mitsuhashi, S.; Nakagawa, S.; Imanishi, T.; Ha, V. T. T.; Nguyen, A. V.; Nguyen, S. T.; Shibayama, K.; Suzuki, M.
10.1101/2020.03.18.996710 — microbiology — Posted on 2020-03-18
1773 Trpm8 modulates thermogenesis in a sex-dependent manner without influencing cold-induced bone loss
Lelis Carvalho, A.; Treyball, A.; Brooks, D. J.; Costa, S.; Reagan, M. R.; Bouxsein, M. L.; Motyl, k.
10.1101/2020.03.18.996694 — physiology — Posted on 2020-03-18
1777 Analysis of circulating-microRNA expression in lactating Holstein cows under summer heat stress
Lee, J.; Lee, S.; Son, J.; Lim, H.; Kim, E.; Kim, D.; Ha, S.; Hur, T.; Lee, S.; Choi, I.
10.1101/2020.03.18.996777 — genomics — Posted on 2020-03-18
1778 APOL1 Variant-Expressing Endothelial Cells Exhibit Autophagic Dysfunction and Mitochondrial Stress
Blazer, A.; Qian, Y.; Schlegel, M. P.; Buyon, J.; Cadwell, K.; Cammer, M.; Heffron, S.; Liang, F.-X.; Mehta-Lee, S.; Niewold, T.; Rasmussen, S.; Clancy, R.
10.1101/2020.03.18.996702 — cell biology — Posted on 2020-03-18
1779 Prospective evaluation of renal function in dogs with chronic mitral valve disease
Martinelli, E.; Crosara, S.; Locatelli, C.; Zanaboni, A. M.; Brambilla, P.; Quintavalla, C.
10.1101/2020.03.18.996785 — pathology — Posted on 2020-03-18
1780 Opa1 overexpression protects from early onset Mpv17-/--related mouse kidney disease
Zeviani, M.; Luna-Sanchez, M.; Beninca, C.; Cerutti, R.; Yeats, A.; Scorrano, L.; Viscomi, C.; Brea Calvo, G.
10.1101/2020.03.18.996561 — pathology — Posted on 2020-03-18
1781 Molecular determinants of SR-B1-dependent Plasmodium sporozoite entry into hepatocytic cells.
Langlois, A.-C.; Manzoni, G.; Vincensini, L.; Coppee, R.; Marinach, C.; Guerin, M.; Huby, T.; Carriere, V.; Cosset, F.-L.; Dreux, M.; Rubinstein, E.; Silvie, O.
10.1101/2020.03.16.994731 — microbiology — Posted on 2020-03-18
1784 Structure of population activity in primary motor cortex for single finger flexion and extension
Arbuckle, S. A.; Weiler, J.; Kirk, E. A.; Rice, C. L.; Schieber, M. H.; Pruszynski, J. A.; Ejaz, N.; Diedrichsen, J.
10.1101/2020.03.17.996124 — neuroscience — Posted on 2020-03-18
1785 The utility of a metagenomics approach for marine biomonitoring
Singer, G. A. C.; Shekarriz, S.; McCarthy, A.; Fahner, N.; Hajibabaei, M.
10.1101/2020.03.16.993667 — ecology — Posted on 2020-03-18
1786 Stress-Induced Dinoflagellate Bioluminescence at the Single Cell Level
Jalaal, M.; Schramma, N.; Dode, A.; de Maleprade, H.; Raufaste, C.; Goldstein, R. E.
10.1101/2020.03.18.997544 — biophysics — Posted on 2020-03-18
1787 High-order interdependencies in the aging brain
Gatica, M.; Cofre, R.; Mediano, P. A. M.; Rosas, F. E.; Orio, P.; Diez, I.; Swinnen, S. P.; Cortes, J. M.
10.1101/2020.03.17.995886 — neuroscience — Posted on 2020-03-18
1789 Integrated lipidomics and proteomics network analysis highlights lipid and immunity pathways associated with Alzheimer's disease
Xu, J.; Bankov, G.; Kim, M.; Wretlind, A.; Lord, J.; Green, R.; Hodges, A.; Hye, A.; Aarsland, D.; Velayudhan, L.; Dobson, R.; Proitsi, P.; Legido-Quigley, C.; AddNeuroMed Consortium,
10.1101/2020.03.18.995464 — neuroscience — Posted on 2020-03-18
1790 A role for the cortex in sleep-wake regulation
Krone, L. B.; Yamagata, T.; Blanco-Duque, C.; Guillaumin, M. C. C.; Kahn, M. C.; Akerman, C. J.; Hoerder-Suabedissen, A.; Molnar, Z.; Vyazovskiy, V. V.
10.1101/2020.03.17.996090 — neuroscience — Posted on 2020-03-18
1793 Human patient SFPQ homozygous mutation is found deleterious for brain and motor development in a zebrafish model
Gordon, P. M.; Efthymiou, S.; Salpietro, V.; Fielding, T.; Borgione, E.; Scuderi, C.; Houlden, H.; Houart, C.
10.1101/2020.03.18.993634 — neuroscience — Posted on 2020-03-18
1794 Lipid metabolic stress in development defines which genetically-susceptible DYT-TOR1A mice develop disease
Cascalho, A.; Foroozandeh, J.; Rous, S.; Martinez Vizcaino, N.; Gallego, S.; Goodchild, R. E.
10.1101/2020.03.18.997247 — neuroscience — Posted on 2020-03-18
1797 Neural activity precedes conscious awareness of being in or out of a transient hallucinatory state
Hugdahl, K.; Craven, A. R.; Johnsen, E.; Ersland, L.; Stoyanov, D.; Kandilarova, S.; Brunvoll, L. S.; Kroken, R. A.; Loberg, E.-M.; Sommer, I. E.
10.1101/2020.03.17.995282 — neuroscience — Posted on 2020-03-18
1801 Subanesthetic ketamine reactivates adult cortical plasticity to restore vision from amblyopia
Grieco, S. F.; Qiao, X.; Zheng, X.; Liu, Y.; Chen, L.; Zhang, H.; Gavornik, J.; Lai, C.; Gandhi, S.; Holmes, T. C.; Xu, X.
10.1101/2020.03.16.994475 — neuroscience — Posted on 2020-03-18
1804 Spatial integration during active tactile sensation drives elementary shape perception
Brown, J.; Oldenburg, I. A.; Telian, G. I.; Griffin, S.; Voges, M.; Jain, V.; Adesnik, H.
10.1101/2020.03.16.994145 — neuroscience — Posted on 2020-03-18
1807 Robust HIV-1 Replication in the Absence of Integrase Function.
Irwan, I. D.; Karnowski, H. L.; Bogerd, H. P.; Tsai, K.; Cullen, B.
10.1101/2020.03.18.997023 — microbiology — Posted on 2020-03-18
1808 Assembly and Annotation of an Ashkenazi Human Reference Genome
Shumate, A.; Zimin, A. V.; Sherman, R. M.; Puiu, D.; Wagner, J. M.; Olson, N. D.; Pertea, M.; Salit, M. L.; Zook, J. M.; Salzberg, S. L.
10.1101/2020.03.18.997395 — genomics — Posted on 2020-03-18
1809 Comparison of long read methods for sequencing and assembly of a plant genome
Murigneux, V.; Rai, S. K.; Furtado, A.; Bruxner, T. J. C.; Tian, W.; Ye, Q.; Wei, H.; Yang, B.; Harliwong, I.; Anderson, E.; Mao, Q.; Drmanac, R.; Wang, O.; Peters, B.; Xu, M.; Wu, P.; Topp, B.; Coin, L. J. M.; Henry, R. J.
10.1101/2020.03.16.992933 — genomics — Posted on 2020-03-18
1815 A RNA-seq characterization of the porcine sperm microbiome.
Godia, M.; Ramayo-Caldas, Y.; Zingaretti, L.; Lopez, S.; Rodriguez-Gil, J. E.; Yeste, M.; Sanchez, A.; Clop, A.
10.1101/2020.03.16.994244 — genomics — Posted on 2020-03-18
1818 Brain network motifs are markers of loss and recovery of consciousness
Duclos, C.; Mahdid, Y.; Nadin, D.; Tarnal, V.; Picton, P.; Vanini, G.; Golmirzaie, G.; Janke, E.; Avidan, M. S.; Kelz, M. B.; Mashour, G. A.; Blain-Moraes, S.
10.1101/2020.03.16.993659 — neuroscience — Posted on 2020-03-18
1821 Anaerobic sulfur oxidation underlies adaptation of a chemosynthetic symbiont to oxic-anoxic interfaces
Bulgheresi, S.; Paredes, G. F.; Viehboek, T.; Lee, R.; Palatinszky, M.; Mausz, M.; Reipert, S.; Schintlmeister, A.; Volland, J.-M.; Hirschfeld, C.; Wagner, M.; Berry, D.; Markert, S.; Koenig, L.
10.1101/2020.03.17.994798 — microbiology — Posted on 2020-03-18
1822 Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death
Lu, K.-Y.; Pasaje, C. F. A.; Srivastava, T.; Loiselle, D. R.; Niles, J.; Derbyshire, E.
10.1101/2020.03.17.995050 — microbiology — Posted on 2020-03-18
1824 Expression of Bacillus cereus Virulence-Related Genes in an Ocular Infection-Related Environment
Coburn, P. S.; Miller, F. C.; Enty, M. A.; Land, C.; LaGrow, A. L.; Mursalin, H.; Callegan, M. C.
10.1101/2020.03.17.995753 — microbiology — Posted on 2020-03-18
1828 Sox2 controls neural stem cell self-renewal through a Fos-centered gene regulatory network
Pagin, M.; Giubbolini, S.; Barone, C.; Sambruni, G.; Zhu, Y.; Ottolenghi, S.; Wei, C.-L.; Nicolis, S. K.
10.1101/2020.03.17.995621 — genetics — Posted on 2020-03-18
1830 Loss of α7 nicotinic acetylcholine receptors in GABAergic interneurons causes sex-dependent impairments in postnatal neurogenesis and cognitive and social behavior
Nacer, S. A.; Otto, S.; Letsinger, A. C.; Strauss DeFilipp, J.; Stevanovic, K. D.; Riddick, N. V.; Nikolova, V.; Cushman, J. D.; Yakel, J. L.
10.1101/2020.03.16.994111 — animal behavior and cognition — Posted on 2020-03-18
1831 Single-cell RNA sequencing of human, macaque, and mouse testes uncovers conserved and divergent features of mammalian spermatogenesis
Shami, A.; Zheng, X.; Munyoki, S.; Ma, Q.; Manske, G.; Green, C.; Sukhwani, M.; Orwig, K.; Li, J.; Hammoud, S.
10.1101/2020.03.17.994509 — genetics — Posted on 2020-03-18
1837 Variation in developmental rates is not linked to environmental unpredictability in annual killifishes
Rowinski, P. K.; Sowersby, W.; Näslund, J.; Eckerström-Liedholm, S.; Gotthard, K.; Rogell, B.
10.1101/2020.03.16.993329 — evolutionary biology — Posted on 2020-03-18
1841 Astrocytes are necessary for blood-brain barrier maintenance in the adult mouse brain
Heithoff, B. P.; Robel, S.; George, K. K.; Phares, A. N.; Zuidhoek, I. A.; Munoz-Ballester, C.
10.1101/2020.03.16.993691 — neuroscience — Posted on 2020-03-18
1843 Neuron-specific cilia loss alters locomotor responses to amphetamine.
Ramos, C.; Roberts, J. B.; Jasso, K. R.; Ten Eyck, T. W.; Setlow, B.; McIntyre, j. C.
10.1101/2020.03.16.994087 — neuroscience — Posted on 2020-03-18
1845 Tau accumulates in Crohn's disease gut
Prigent, A.; Chapelet, G.; de Guilhem de Lataillade, A.; Oullier, T.; Durieu, E.; Bourreille, A.; Duchalais, E.; Hardonniere, K.; Neunlist, M.; Noble, W.; Kerdine-Romer, S.; Derkinderen, P.; Rolli-Derkinderen, M.
10.1101/2020.03.16.979534 — neuroscience — Posted on 2020-03-18
1848 Ebola virus requires phosphatidylserine scrambling activity for efficient budding and optimal infectivity
Acciani, M. D.; Lay-Mendoza, M. F.; Havranek, K. E.; Linn, O. L.; Duncan, A. M.; Iyer, H.; Brindley, M. A.
10.1101/2020.03.16.994012 — microbiology — Posted on 2020-03-18
1851 Sustained Release of IL-2 Using an Injectable Hydrogel Prevents Autoimmune Diabetes
Nagy, N.; Kaber, G.; Kratochvil, M.; Kuipers, H.; Ruppert, S.; Yadava, K.; Yang, J.; Heilshorn, S.; Long, A.; Pugliese, A.; Bollyky, P.
10.1101/2020.03.15.993063 — immunology — Posted on 2020-03-18
1853 Foundation species across a latitudinal gradient in China
Qiao, X.; Zhang, J.; Xu, Y.; Mi, X.; Cao, M.; Ye, W.; Jin, G.; Hao, Z.; Wang, X.; Wang, X.; Tian, S.; Li, X.; Xiang, W.; Liu, Y.; Shao, Y.; Xu, K.; Sang, W.; Zeng, F.; Jiang, M.; Ren, H.; Ellison, A. M.
10.1101/2020.03.15.986182 — ecology — Posted on 2020-03-18
1854 Loss of mu and delta opioid receptors on neurons expressing dopamine receptor D1 has no effect on reward sensitivity
Harda, Z.; Spyrka, J.; Jastrzebska, K.; Szumiec, L.; Bryksa, A.; Klimczak, M.; Polaszek, M.; Golda, S.; Zajdel, J.; Blasiak, A.; Rodriguez Parkitna, J. M.
10.1101/2020.03.18.996454 — neuroscience — Posted on 2020-03-18
1855 Characterization of the SARS-CoV-2 Spike in an Early Prefusion Conformation
Li, T.; Zheng, Q.; Yu, H.; Wu, D.; Xue, W.; Zhang, Y.; Huang, X.; Zhou, L.; Zhang, Z.; Zha, Z.; Chen, T.; Wang, Z.; Chen, J.; Sun, H.; Deng, T.; Wang, Y.; Chen, Y.; Zhao, Q.; Zhang, J.; Gu, Y.; Li, S.; Xia, N.
10.1101/2020.03.16.994152 — molecular biology — Posted on 2020-03-18
1857 Biomechanical properties of a buzz-pollinatedflower
Garcia de Brito, V. L.; Pereira Nunes, C. E.; Rocha Resende, C.; Montealegre-Zapata, F.; Vallejo-Marin, M.
10.1101/2020.03.17.995746 — plant biology — Posted on 2020-03-18
1858 LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate
Jin, R.; Klasfeld, S.; Garcia, M. F.; Xiao, J.; Han, S.-K.; Konkol, A.; Zhu, Y.; Wagner, D.
10.1101/2020.03.16.994418 — plant biology — Posted on 2020-03-18
1859 'Macrobot' - an automated segmentation-based system for powdery mildew disease quantification
Lueck, S.; Strickert, M.; Lorbeer, M.; Melchert, F.; Backhaus, A.; Kilias, D.; Seiffert, U.; Schweizer, P.; Djamei, A.; Douchkov, D.
10.1101/2020.03.16.993451 — plant biology — Posted on 2020-03-18
1862 OsNLP4 is required for nitrate assimilation gene expressions and nitrate-dependent growth in rice
Wang, M.; Hasegawa, T.; Hayashi, M.; Ohmori, Y.; Yano, K.; Teramoto, S.; Kamiya, T.; Fujiwara, T.
10.1101/2020.03.16.993733 — plant biology — Posted on 2020-03-18
1865 SARS-CoV-2 receptor ACE2 and TMPRSS2 are predominantly expressed in a transient secretory cell type in subsegmental bronchial branches
Lukassen, S.; Chua, R. L.; Trefzer, T.; Kahn, N. C.; Schneider, M. A.; Muley, T.; Winter, H.; Meister, M.; Veith, C.; Boots, A. W.; Hennig, B. P.; Kreuter, M.; Conrad, C.; Eils, R.
10.1101/2020.03.13.991455 — genomics — Posted on 2020-03-18
1867 The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans
Heissenberger, C.; Krammer, T. L.; Rollins, J. A.; Nagelreiter, F.; Stocker, I.; Wacheul, L.; Shpylovyi, A.; Snow, S.; Grillari, J.; Rogers, A.; Lafontaine, D. L.; Schosserer, M.
10.1101/2020.03.16.993469 — cell biology — Posted on 2020-03-18
1868 GAS6-AXL signaling triggers actin remodeling and macropinocytosis that drive cancer cell invasion
Zdzalik-Bielecka, D.; Poswiata, A.; Kozik, K.; Jastrzebski, K.; Schink, K. O.; Brewinska-Olchowik, M.; Piwocka, K.; Stenmark, H.; Miaczynska, M.
10.1101/2020.03.15.993147 — cell biology — Posted on 2020-03-18
1871 A tissue- and organ-based cell biological atlas of obesity-related human genes and cellular pathways
Tavassoly, I.; Barbieri, V.; van Hasselt, C.; Martinez, P.; Sobie, E. A.; Hansen, J.; Azeloglu, E.; Goldfarb, J.; Sanseau, P.; Rajpal, D. K.; Iyengar, R.
10.1101/2020.03.16.993824 — systems biology — Posted on 2020-03-18
1872 Blood vessel occlusion by Cryptococcus neoformans is a mechanism for hemorrhagic dissemination of infection
Gibson, J.; Bojarczuk, A.; Evans, R. J.; Kamuyango, A.; Hotham, R.; Lagendijk, A. K.; Hogan, B. M.; Ingham, P. W.; Renshaw, S.; Johnston, S.
10.1101/2020.03.17.995571 — pathology — Posted on 2020-03-18
1874 YAP orchestrates heterotypic endothelial cell communication via HGF/c-MET signaling in liver tumorigenesis
Thomann, S.; Weiler, S. M.; Marquard, S.; Ball, C. R.; Toth, M.; Wei, T.; Sticht, C.; de la Torre, C.; Ryschich, E.; Ermakova, O.; Mogler, C.; Kazdal, D. N.; Gretz, N.; Glimm, H.; Rempel, E.; Schirmacher, P.; Breuhahn, K.
10.1101/2020.03.17.995225 — cancer biology — Posted on 2020-03-18
1877 Quantitative properties of the creation and activation of a cell-intrinsic engram
Gallistel, C. R.; Johansson, F.; Jirenhed, D.-A.; Rasmussen, A.; Ricci, M.; Hesslow, G.
10.1101/2020.03.17.995258 — bioinformatics — Posted on 2020-03-18
1881 The landscape of longevity across phylogeny
Podolskiy, D. I.; Avanesov, A.; Tyshkovskiy, A.; Petrascheck, M.; Kaeberlein, M.; Gladyshev, V. N.
10.1101/2020.03.17.995993 — systems biology — Posted on 2020-03-18
1884 Microbial resource management for ex situ biomethanation of hydrogen at alkaline pH
Logrono, W.; Popp, D.; Kleinsteuber, S.; Sträuber, H.; Harms, H.; Nikolausz, M.
10.1101/2020.03.18.995811 — bioengineering — Posted on 2020-03-18
1885 Histone Acetyltransferase 1 is Required for DNA Replication Fork Function and Stability
Agudelo Garcia, P. A.; Lovejoy, C.; Nagarajan, P.; Park, D.; Popova, L. V.; Freitas, M. A.; Parthun, M. R.
10.1101/2020.03.17.989434 — biochemistry — Posted on 2020-03-18
1886 Alterations in the human plasma lipidome in response to Tularemia vaccination
Maner-Smith, K.; Ford, D. A.; Goll, J. B.; Khadka, M.; Jensen, T. L.; Colucci, J. K.; Gelber, C. E.; Albert, C. J.; Bosinger, S. E.; Franke, J. D.; Natrajan, M.; Rouphael, N.; Johnson, R. A.; Sanz, P.; Anderson, E. J.; Hoft, D. F.; Mulligan, M.; Ortlund, E. A.
10.1101/2020.03.16.994525 — biochemistry — Posted on 2020-03-18
1887 Asparagine signals mitochondrial respiration and can be targeted to impair tumour growth
Christofk, H. R.; Krall, A. S.; Mullen, P. J.; Surjono, F.; Momcilovic, M.; Schmid, E. W.; Halbrook, C. J.; Thambundit, A.; Mittelman, S. D.; Lyssiotis, C. A.; Shackelford, D. B.; Knott, S. R.
10.1101/2020.03.17.995670 — cancer biology — Posted on 2020-03-18
1888 An easily adopted murine model of distal pancreatectomy for investigating immunotherapy efficacy in resectable pancreatic adenocarcinoma
Baxter, K. E.; Tanese de Souza, C.; Tai, L.-H.; Yaghini, P.; Daneshmand, M.; Bell, J. C.; Lichty, B. D.; Kennedy, M. A.; Auer, R. C.
10.1101/2020.03.17.990903 — cancer biology — Posted on 2020-03-18
1889 Patient-derived xenografts and organoids model therapy response in prostate cancer
Karkampouna, S.; La Manna, F.; De Filippo, M. R.; Kiener, M.; De Menna, M.; Zoni, E.; Grosjean, J.; Klima, I.; Garofoli, A.; Bolis, M.; Theurillat, J.-P.; Genitsch, V.; Keller, D.; Booij, T.; Stirnimann, C.; Eng, K.; Sboner, A.; Ng, C. K.; Piscuoglio, S.; Gray, P. C.; Spahn, M.; Rubin, M. A.; Thalmann, G. N.; Kruithof-de Julio, M.
10.1101/2020.03.17.994350 — cancer biology — Posted on 2020-03-18
1890 miRNome profiling of clonal stem cells in Ph+ CML
Ruiz, M. S.; Sanchez, M. B.; Bonecker, S.; Furtado, C.; Koile, D.; Yankilevich, P.; Cranco, S.; Custidiano, M. d. R.; Freitas, J.; Moiraghi, B.; Perez, M. A.; Pavlovsky, C.; Varela, A. I.; Ventriglia, V.; Sanchez Avalos, J. C.; Larripa, I.; Zalcberg, I.; Mordoh, J.; Valent, P.; Bianchini, M.
10.1101/2020.03.16.989194 — cancer biology — Posted on 2020-03-18
1898 An 1,4-α-glucosyltransferase defines a new maltodextrin catabolism scheme in Lactobacillus acidophilus
Andersen, S.; Moeller, M. S.; Poulsen, J.-C. N.; Pichler, M. J.; Svensson, B.; Goh, Y.-J.; Lo Leggio, L.; Abou Hachem, M.
10.1101/2020.03.17.996314 — biochemistry — Posted on 2020-03-18
1901 Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP
Perederina, A.; Li, D.; Lee, H.; Bator, C.; Berezin, I.; Hafenstein, S. L.; Krasilnikov, A. S.
10.1101/2020.03.17.996132 — biochemistry — Posted on 2020-03-18
1902 Structure of human ferroportin reveals molecular basis of iron homeostasis
Billesboelle, C.; Azumaya, C.; Kretsch, R. C.; Powers, A. S.; Gonen, S.; Schneider, S.; Arvedson, T.; Dror, R.; Cheng, Y.; Manglik, A.
10.1101/2020.03.16.993006 — biochemistry — Posted on 2020-03-18
1905 Discovering biomarkers of chemotherapy resistance using in vitro evolution in haploid human cells
Jado, J. C.; Dow, M.; Fonseca, G.; Carolino, K.; Ideker, T.; Carter, H.; Winzeler, E.
10.1101/2020.03.17.982181 — cancer biology — Posted on 2020-03-18
1906 Development of a new class of liver receptor homolog-1 (LRH-1) agonists by photoredox conjugate addition
Cornelison, J. L.; Cato, M. L.; Johnson, A. M.; D'Agostino, E. H.; Melchers, D.; Patel, A. B.; Mays, S. G.; Houtman, R.; Ortlund, E. A.; Jui, N. T.
10.1101/2020.03.16.994400 — biochemistry — Posted on 2020-03-18
1907 The vesicular trafficking system component MIN7 is required for minimizing Fusarium graminearum infection
Machado Wood, A. K.; Panwar, V.; Grimwade-Mann, M.; Ashfield, T.; Hammond-Kosack, K. E.; Kanyuka, K.
10.1101/2020.03.16.994095 — plant biology — Posted on 2020-03-18
1910 Hybrid quantum dot - collagen extracellular matrices for in situ optical monitoring of cardiomyocyte activity by two photon fluorescence
Jooken, S.; de Coene, Y.; Deschaume, O.; Krylychkina, O.; Verbiest, T.; Clays, K.; Callewaert, G.; Bartic, C.
10.1101/2020.03.18.990846 — biophysics — Posted on 2020-03-18
1913 proABC-2: PRediction Of AntiBody Contacts v2 and its application to information-driven docking
Ambrosetti, F.; Olsed, T. H.; Olimpieri, P. P.; Jimenez-Garcia, B.; Milanetti, E.; Marcatilli, P.; Bonvin, A. M. J. J.
10.1101/2020.03.18.967828 — bioinformatics — Posted on 2020-03-18
1914 CHOmics: a web-based tool for multi-omics data analysis and interactive visualization in CHO cell lines
Lin, D.; Yalamanchili, H.; Zhang, X.; Lewis, N. E.; Alves, C. L.; Groot, J.; Arnsdorf, J.; Peterson Bjorn, S.; Wulff, T.; Rude Voldborg, B. G.; Zhou, Y.; Zhang, B.
10.1101/2020.03.17.995290 — bioinformatics — Posted on 2020-03-18
1917 Mating type specific transcriptomic response to sex inducing pheromone in the pennate diatom Seminavis robusta
Bilcke, G.; Van den Berge, K.; De Decker, S.; Bonneure, E.; Poulsen, N.; Bulankova, P.; Osuna-Cruz, C. M.; Dickenson, J.; Sabbe, K.; Pohnert, G.; Vandepoele, K.; Mangelinckx, S.; Clement, L.; De Veylder, L.; Vyverman, W.
10.1101/2020.03.16.987719 — molecular biology — Posted on 2020-03-18
1918 TRTools: a toolkit for genome-wide analysis of tandem repeats
Mousavi, N.; Margoliash, J.; Pusarla, N.; Saini, S.; Yanicky, R.; Gymrek, M.
10.1101/2020.03.17.996033 — bioinformatics — Posted on 2020-03-18
1919 Bio-upcycling of polyethylene terephthalate
Tiso, T.; Narancic, T.; Wei, R.; Pollet, E.; Beagan, N.; Schroeder, K.; Honak, A.; Jiang, M.; Kenny, S.; Wierckx, N.; Perrin, R.; Averous, L.; Zimmermann, W.; O'Connor, K. E.; Blank, L. M.
10.1101/2020.03.16.993592 — bioengineering — Posted on 2020-03-18
1920 Single-shot Mesoporous Silica Rods Scaffold for Induction of Humoral Responses Against Small Antigens
Dellacherie, M. O.; Li, A.; Lu, B. Y.; Verbeke, C. S.; Gu, L.; Stafford, A.; Doherty, E. J.; Mooney, D. J.
10.1101/2020.03.17.993808 — bioengineering — Posted on 2020-03-18
1922 Substrate deformation regulates DRM2-mediated DNA methylation in plants
Fang, J.; Leichter, S. M.; Jiang, J.; Biswal, M.; Lu, J.; Zhang, Z.-M.; Ren, W.; Zhai, J.; Cui, Q.; Zhong, X.; Song, J.
10.1101/2020.03.17.995522 — biochemistry — Posted on 2020-03-18
1923 Whole exome sequencing identifies novel DYT1 dystonia-associated genome variants as potential disease modifiers
Hu, C.-F.; Wu, S.-P.; Gant Luxton, G. W.; Lee, F.-C.; Hsu, C.-S.; Huang, S.-M.; Hong, J.-S.
10.1101/2020.03.15.993113 — genetics — Posted on 2020-03-18
1924 DNA methylation is indispensable for leukemia inhibitory factor dependent embryonic stem cells reprogramming
Bao, S.; Wu, B.; Li, Y.; Li, B.; Zhang, B.; Wang, Y.; Li, L.; Peng, G.; Fu, Y.; Li, S.; Tang, F.; Li, X.
10.1101/2020.03.17.994939 — cell biology — Posted on 2020-03-18
1925 Self-organized Toll-8/Cirl GPCR asymmetry drives planar polarized cell contractility
Lavalou, J.; Mao, Q.; Harmansa, S.; Kerridge, S.; Lellouch, A. C.; Philippe, J.-M.; Audebert, S.; Camoin, L.; Lecuit, T.
10.1101/2020.03.16.993758 — developmental biology — Posted on 2020-03-18
1927 Derivation of macaque trophoblast stem cells
Kropp Schmidt, J.; Meyer, M. G.; Wiepz, G. J.; Block, L. N.; Dusek, B. M.; Kroner, K. M.; Bertogliat, M. J.; Keding, L. T.; Koenig, M. R.; Mean, K. D.; Golos, T. G.
10.1101/2020.03.17.995407 — developmental biology — Posted on 2020-03-18
1928 A CTGF-YAP regulatory pathway is essential for angiogenesis and barriergenesis in the retina
Moon, S.; Lee, S.; Caesar, J.; Pruchenko, S.; Andrew, L.; Knowles, J. A.; Sinon, J.; Chaqour, B.
10.1101/2020.03.16.994293 — developmental biology — Posted on 2020-03-18
1930 Rational design and implementation of a chemically inducible hetero-trimerization system
Wu, H. D.; Kikuchi, M.; Dagliyan, O.; Aragaki, A. K.; Nakamura, H.; Dokholyan, N. V.; Umehara, T.; Inoue, T.
10.1101/2020.03.16.994277 — cell biology — Posted on 2020-03-18
1933 Boron induces osteogenesis by stimulating NaBC1 in cooperation with BMPR1A
Rico, P.; Rodrigo-Navarro, A.; Sanchez Perez, L.; Salmeron-Sanchez, M.
10.1101/2020.03.17.995001 — cell biology — Posted on 2020-03-18
1934 Rottlerin ameliorates DSS-induced colitis by improving intestinal barrier function via activation of the Epac-2/Rap-1 signaling pathway.
Song, X.; Zuo, L.; Wang, L.; Zhu, Z.; Tao, J.; Jiang, Y.; Wu, X.; Wang, Z.; Nian, J.; Xiang, P.; Zhang, X.; Zhao, H.; Yu, L.; Li, J.; Hu, J.
10.1101/2020.03.16.994582 — cell biology — Posted on 2020-03-18
1936 Drosophila Histone Locus Body assembly and function involves multiple interactions
Koreski, K. P.; Rieder, L. E.; McLain, L. M.; Marzluff, W. F.; Duronio, R. J.
10.1101/2020.03.16.994483 — cell biology — Posted on 2020-03-18
1937 Clusters of bacterial RNA polymerase are biomolecular condensates that assemble through liquid-liquid phase separation
Ladouceur, A.-M.; Parmar, B.; Biedzinski, S.; Wall, J.; Tope, S. G.; Cohn, D.; Kim, A.; Soubry, N.; REYES LAMOTHE, R.; Weber, S. C.
10.1101/2020.03.16.994491 — cell biology — Posted on 2020-03-18
1938 Prospects and limitations of expansion microscopy in chromatin ultrastructure determination
Kubalova, I.; Schmidt Cernohorska, M.; Huranova, M.; Weisshart, K.; Houben, A.; Schubert, V.
10.1101/2020.03.16.994186 — cell biology — Posted on 2020-03-18
1941 HiCanu: accurate assembly of segmental duplications, satellites, and allelic variants from high-fidelity long reads
Nurk, S.; Walenz, B. P.; Rhie, A.; Vollger, M. R.; Logsdon, G. A.; Grothe, R.; Miga, K. H.; Eichler, E. E.; Phillippy, A. M.; Koren, S.
10.1101/2020.03.14.992248 — bioinformatics — Posted on 2020-03-18
1942 Structure of a Single Chain H2A/H2B Dimer
Warren, C.; Bonanno, J. B.; Almo, S. C.; Shechter, D.
10.1101/2020.03.15.992685 — biochemistry — Posted on 2020-03-18
1943 Choroid plexus APP regulates adult brain proliferation and animal behavior
Arnaud, K.; Oliveira Moreira, V.; Vincent, J.; Dallerac, G.; Le Poupon, C.; Richter, M.; Müller, U. C.; Rond-Reig, L.; Prochiantz, A.; Di Nardo, A. A.
10.1101/734103 — neuroscience — Posted on 2020-03-18
1945 No one-size-fits-all solution to clean GBIF
Zizka, A.; Antunes Carvalho, F.; Calvente, A.; Rocio Baez-Lizarazo, M.; Cabral, A.; Ramos Coelho, J. F.; Colli-Silva, M.; Ramos Fantinati, M.; Ferreira Fernandes, M.; Ferreira-Araujo, T.; Gondim Lambert Moreira, F.; da Cunha Santos, N. M.; Borges Santos, T. A.; Clicia dos Santos-Costa, R.; Cabreirinha Serrano, F.; Alves da Silva, A. P.; Cavalcante de Souza, P. G.; Calisto Tomaz, E.; de Souza Soares, A.; Fonseca Vale, V.; Vieira, T. L.; Antonelli, A.
10.1101/2020.03.12.974543 — ecology — Posted on 2020-03-18
1949 Early-life microbial intervention reduces colitis risk promoted by antibiotic-induced gut dysbiosis
Miyoshi, J.; Miyoshi, S.; Delmont, T. O.; Cham, C.; Lee, S. T. M.; Sakatani, A.; Yang, K.; Shan, Y.; Kiefl, E.; Yousef, M.; Crosson, S.; Sogin, M.; Antonopoulos, D. A.; Eren, A. M.; Leone, V.; Chang, E. B.
10.1101/2020.03.11.987412 — microbiology — Posted on 2020-03-18
1950 Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning & reduces neurodegeneration
Ryan, V. H.; Perdikari, T. M.; Naik, M. T.; Saueressig, C. F.; Lins, J.; Dignon, G. L.; Mittal, J.; Hart, A. C.; Fawzi, N. L.
10.1101/2020.03.15.992768 — biochemistry — Posted on 2020-03-18
1951 Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning & reduces neurodegeneration
Ryan, V. H.; Perdikari, T. M.; Naik, M. T.; Saueressig, C. F.; Lins, J.; Dignon, G. L.; Mittal, J.; Hart, A. C.; Fawzi, N. L.
10.1101/2020.03.15.992768 — biochemistry — Posted on 2020-03-18
1953 Chemical modification of proteins by insertion of synthetic peptides using tandem protein trans-splicing
Khoo, K. K.; Galleano, I.; Gasparri, F.; Wieneke, R.; Harms, H.; Poulsen, M. H.; Chua, H. C.; Wulf, M.; Tampe, R.; Pless, S. A.
10.1101/2020.01.31.925495 — synthetic biology — Posted on 2020-03-18
1954 Reshaping of the Arabidopsis thaliana proteome landscape and co-regulation of proteins in development and immunity
Bassal, M.; Majovsky, P.; Thieme, D.; Herr, T.; Abukhalaf, M.; Ayash, M.; Al Shweiki, M. R.; Proksch, C.; Hmedat, A.; Ziegler, J.; Neumann, S.; Hoehenwarter, W.
10.1101/2020.03.09.978627 — plant biology — Posted on 2020-03-18
1956 Altered kinetics of circulating progenitor cells in cardiopulmonary bypass (CPB) associated vasoplegic patients: An observational study
Nandi, S.; Kumari, C.; Potunuru, U. R.; Nathan, A. A.; Gopal, J.; Menon, G. I.; Siddharthan, R.; Dixit, M.; Thangaraj, P. R.
10.1101/2020.03.11.987099 — physiology — Posted on 2020-03-18
1958 The dorsal striatum sets the sensitivity to effort
Jurado-Parras, M.-T.; Safaie, M.; Sarno, S.; Louis, J.; Karoutchi, C.; Berret, B.; Robbe, D.
10.1101/2020.03.13.991000 — neuroscience — Posted on 2020-03-18
1960 SARS-CoV-2 sensitive to type I interferon pretreatment.
Lokugamage, K. G.; Hage, A.; Schindewolf, C.; Rajsbaum, R.; Menachery, V. D.
10.1101/2020.03.07.982264 — microbiology — Posted on 2020-03-18
1962 A wave of embryonic bipotent T/lymphoid tissue inducer progenitors regulates the maturation of medullary thymic epithelial cells.
Elsaid, R.; Meunier, S.; Defranoux, O.; Soraes-da-Silva, F.; Perchet, T.; Iturri, L.; Freyer, L.; Vieira, P.; Pereira, P.; Golub, R.; Bandeira, A.; Gomez Perdiguero, E.; Cumano, A.
10.1101/791103 — immunology — Posted on 2020-03-18
1963 Identification of characteristic genomic markers in human hepatoma Huh7 and Huh7.5.1-8 cell lines
Kawamoto, M.; Yamaji, T.; Saito, K.; Endo, T.; Fukasawa, M.; Hanada, K.; Osada, N.
10.1101/2020.02.17.953281 — genomics — Posted on 2020-03-18
1965 Genomic signals of admixture and reinforcement between two closely related species of European sepsid flies
Giesen, A.; Blanckenhorn, W. U.; Schaefer, M. A.; Shimizu, K. K.; Shimizu-Inatsugi, R.; Misof, B.; Niehuis, O.; Podsiadlowski, L.; Lischer, H. E. L.; Aeschbacher, S.; Kapun, M.
10.1101/2020.03.11.985903 — evolutionary biology — Posted on 2020-03-18
1967 Insulin-like Growth Factor-1 Regulates the Mechanosensitivity of Chondrocytes by Modulating TRPV4
Trompeter, N. S.; Gardinier, J. D.; DeBarros, V. M.; Boggs, M.; Hurd, L.; Duncan, R. L.
10.1101/2020.03.10.985713 — cell biology — Posted on 2020-03-18
1968 Gut Microbiome Pattern Reflects Healthy Aging and Predicts Extended Survival in Humans
Wilmanski, T.; Diener, C.; Rappaport, N.; Patwardhan, S.; Wiedrick, J.; Lapidus, J.; Earls, J. C.; Zimmer, A.; Glusman, G.; Robinson, M.; Yurkovich, J. T.; Kado, D. M.; Cauley, J. A.; Zmuda, J.; Lane, N. E.; Magis, A. T.; Lovejoy, J. C.; Hood, L.; Gibbons, S. M.; Orwoll, E. S.; Price, N. D.
10.1101/2020.02.26.966747 — bioinformatics — Posted on 2020-03-18
1972 S-Trap eliminates cell culture media polymeric surfactants for effective proteomic analysis of mammalian cell bioreactor supernatants
Zacchi, L. F.; Roche Recinos, D.; Otte, E.; Aitken, C.; Hunt, T.; Sandford, V.; Lee, Y. Y.; Schulz, B. L.; Howard, C. B.
10.1101/2020.02.17.951798 — biochemistry — Posted on 2020-03-18
1975 Intraspecific difference among herbivore lineages and their host-plant specialization drive the strength of trophic cascades
Sentis, A.; Bertram, R.; Dardenne, N.; Simon, J.-C.; Magro, A.; Pujol, B.; Danchin, E.; Hemptinne, J.-L.
10.1101/722140 — ecology — Posted on 2020-03-18
1978 Drosophila PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity
Ghosh, A. C.; Tattikota, S. G.; Liu, Y.; Comjean, A.; Hu, Y.; Barrera, V.; Ho Sui, S. J.; Perrimon, N.
10.1101/2019.12.23.887059 — genetics — Posted on 2020-03-18
1979 A universal chromosome identification system for maize and wild Zea species
Tomaz Braz, G.; do Vale Martins, L.; Zhang, T.; S. Albert, P.; A. Birchler, J.; Jiang, J.
10.1101/2020.01.22.915942 — genetics — Posted on 2020-03-18
1981 Turnover modulates the need for a cost of resistance in adaptive therapy
Strobl, M. A. R.; West, J.; Viossat, Y.; Damaghi, M.; Robertson-Tessi, M.; Brown, J.; Gatenby, R.; Maini, P.; Anderson, A.
10.1101/2020.01.22.914366 — cancer biology — Posted on 2020-03-18
1984 Loss of prdm1a accelerates melanoma onset and progression
Iwanaga, R.; Truong, B.; Lambert, K.; Vyas, R.; Orlicky, D.; Shellman, Y.; Tan, A.-C.; Ceol, C.; Artinger, K.
10.1101/2019.12.20.884767 — cancer biology — Posted on 2020-03-18
1986 Chamaeleo: a robust library for DNA storage coding schemes
Ping, Z.; Zhang, H.; Chen, S.; Zhuang, Q.; Zhu, S.; Shen, Y.
10.1101/2020.01.02.892588 — bioinformatics — Posted on 2020-03-18
1989 Introgression across evolutionary scales suggests reticulation contributes to Amazonian tree diversity
Schley, R. J.; Pennington, T.; Perez-Escobar, O. A.; Helmstetter, A. J.; de la Estrella, M.; Larridon, I.; Sabino Kikuchi, I. A. B.; Barraclough, T. G.; Forest, F.; Klitgaard, B. B.
10.1101/2019.12.12.873927 — evolutionary biology — Posted on 2020-03-18
1992 Localizing components of shared transethnic genetic architecture of complex traits from GWAS summary data
Shi, H.; Burch, K. S.; Johnson, R.; Freund, M. K.; Kichaev, G.; Mancuso, N.; Manuel, A. M.; Dong, N.; Pasaniuc, B.
10.1101/858431 — genomics — Posted on 2020-03-18
1993 Relative genomic impacts of translocation history, hatchery practices, and farm selection in Pacific oyster Crassostrea gigas throughout the Northern Hemisphere
Sutherland, B. J. G.; Rycroft, C.; Ferchaud, A.-L.; Saunders, R.; Li, L.; Liu, S.; Chan, A. M.; Otto, S.; Suttle, C. A.; Miller, K. M.
10.1101/847467 — genetics — Posted on 2020-03-18
1994 Ecological and evolutionary drivers of hemoplasma infection and bacterial genotype sharing in a Neotropical bat community
Becker, D.; Speer, K.; Brown, A.; Fenton, M. B.; Washburne, A.; Altizer, S.; Streicker, D.; Plowright, R.; Chizhikov, V.; Simmons, N. B.; Volokhov, D.
10.1101/2019.12.21.885921 — ecology — Posted on 2020-03-18
1997 Developmental function and state transitions of a gene expression oscillator in C. elegans
Meeuse, M. W. M.; Hauser, Y. P.; Hendriks, G.-J.; Eglinger, J.; Bogaarts, G.; Tsiairis, C.; Grosshans, H.
10.1101/755421 — systems biology — Posted on 2020-03-18
2000 White matter microstructure in attention-deficit/hyperactivity disorder: a systematic tractography study in 654 individuals
Damatac, C. G.; Zwiers, M.; Chauvin, R. J. M.; van Rooij, D.; Akkermans, S. E. A.; Naaijen, J.; Hoekstra, P. J.; Hartman, C. A.; Oosterlaan, J.; Franke, B.; Buitelaar, J. K.; Beckmann, C. F.; Sprooten, E.
10.1101/787713 — neuroscience — Posted on 2020-03-18
2001 Mate discrimination among subspecies through a conserved olfactory pathway
Khallaf, M. A.; Auer, T. O.; Grabe, V.; Depetris-Chauvin, A.; Ammagarahalli, B.; Zhang, D.-D.; Lavista-Llanos, S.; Kaftan, F.; Weissflog, J.; Matzkin, L. M.; Rollmann, S.; Loefstedt, C.; Svatos, A.; Dweck, H. K.; Sachse, S.; Benton, R.; Hansson, B. S.; Knaden, M.
10.1101/854364 — neuroscience — Posted on 2020-03-18
2002 Cholesterol recognition motifs in the transmembrane domain of the tyrosine kinase receptor family: the case for TRKB
Cannarozzo, C.; Fred, S. M.; Girych, M.; Biojone, C.; Enkavi, G.; Rog, T.; Vattulainen, I.; Casarotto, P. C.; Castren, E.
10.1101/734012 — neuroscience — Posted on 2020-03-18
2003 Flexible coordinator and switcher hubs for adaptive task control
Cocuzza, C. V.; Ito, T.; Schultz, D. H.; Bassett, D. S.; Cole, M. W.
10.1101/822213 — neuroscience — Posted on 2020-03-18
2004 CRISPR-Cas9 generated Pompe knock-in murine model exhibits early-onset hypertrophic cardiomyopathy and skeletal muscle weakness
Huang, J. Y.; Kan, S.-H.; Sandfeld, E. K.; Dalton, N. D.; Rangel, A. D.; Chan, Y.; Davis-Turak, J.; Neumann, J.; Wang, R. Y.
10.1101/780320 — molecular biology — Posted on 2020-03-18
2008 Impacts of the Toba eruption and montane forest expansion on diversification in Sumatran parachuting frogs (Rhacophorus)
O'Connell, K. A.; Oaks, J. R.; Hamidy, A.; Shaney, K. J.; Kurniawan, N.; Smith, E. N.; Fujita, M. K.
10.1101/843664 — evolutionary biology — Posted on 2020-03-18
2009 Life history genomic regions explain differences in Atlantic salmon marine diet specialization
Aykanat, T.; Rasmussen, M.; Ozerov, M.; Niemela, E.; Paulin, L.; Vaha, J.-P.; Hindar, K.; Wennevik, V.; Pedersen, T.; Svenning, M.-A.; Primmer, C. R.
10.1101/754440 — ecology — Posted on 2020-03-18
2010 A process-based metacommunity framework linking local and regional scale community ecology
Thompson, P. L.; Guzman, L. M.; De Meester, L.; Horvath, Z.; Ptacnik, R.; Vanschoenwinkel, B.; Viana, D. S.; Chase, J.
10.1101/832170 — ecology — Posted on 2020-03-18
2011 TRAF6 controls spinogenesis instructing synapse density and neuronal activity through binding neuroplastin
Kumar Vemula, S.; Malci, A.; Junge, L.; Lehmann, A.-C.; Rama, R.; Hradsky, J.; Matute, R. A.; Weber, A.; Prigge, M.; Naumann, M.; Kreutz, M. R.; Seidenbecher, C. I.; Gundelfinger, E. D.; Herrera-Molina, R.
10.1101/768341 — cell biology — Posted on 2020-03-18
2014 Detecting regions of differential abundance betweenscRNA-Seq datasets
Zhao, J.; Jaffe, A.; Li, H.; Lindenbaum, O.; Cheng, X.; Flavell, R.; Kluger, Y.
10.1101/711929 — bioinformatics — Posted on 2020-03-18
2017 Metabolomics profiling reveals new aspects of dolichol biosynthesis in Plasmodium falciparum
Zimbres, F. M.; Valenciano, A. L.; Merino, E. F.; Holderman, N. R.; Florentin, A.; He, G.; Gawarecka, K.; Skorupinska-Tudek, K.; Fernandez-Murga, M. L.; Swiezewska, E.; Wang, X.; Muralidharan, V.; Cassera, M. B.
10.1101/698993 — biochemistry — Posted on 2020-03-18
2019 Dissociable mechanisms govern when and how strongly reward attributes affect decisions
Maier, S. U.; Raja Beharelle, A.; Polania, R.; Ruff, C. C.; Hare, T. A.
10.1101/434860 — neuroscience — Posted on 2020-03-18
2023 An intron proximal to a PTC enhances NMD in Saccharomyces cerevisiae
Wen, J.; He, M.; Petric, M.; Marzi, L.; Wang, J.; Piechocki, K.; McLeod, T.; Singh, A. K.; Dwivedi, V.; Brogna, S.
10.1101/149245 — molecular biology — Posted on 2020-03-18
2024 Tightly regulated, yet flexible, directional switching mechanism of a rotary motor
Afanzar, O.; Di Paolo, D.; Eisenstein, M.; Levi, K.; Plochowietz, A.; Kapanidis, A. N.; Berry, R. M.; Eisenbach, M.
10.1101/642140 — microbiology — Posted on 2020-03-18
2026 Estimating heritability and its enrichment in tissue-specific gene sets in admixed populations
Luo, Y.; Li, X.; Wang, X.; Gazal, S.; Mercader, J. M.; Neale, B.; Florez, J. C.; Auton, A.; Price, A.; Finucane, H. K.; Raychaudhuri, S.
10.1101/503144 — genetics — Posted on 2020-03-18
2029 The polyol pathway is a crucial glucose sensor in Drosophila
Sano, H.; Nakamura, A.; Yamane, M.; Niwa, H.; Nishimura, T.; Kojima, M.
10.1101/2020.03.16.993170 — physiology — Posted on 2020-03-17
2030 Mitochondrial dysfunction underlying sporadic inclusion body myositis is ameliorated by the mitochondrial homing drug MA-5
Oikawa, Y.; Izumi, R.; Koide, M.; Hagiwara, Y.; Kanzaki, M.; Suzuki, N.; Kikuchi, K.; Matsuhashi, T.; Akiyama, Y.; Ichijo, M.; Toyohara, T.; Suzuki, T.; Mishima, E.; Akiyama, Y.; Ogata, Y.; Suzuki, C.; Aoki, M.; Itoi, I.; Hayashi, K.-i.; Kure, S.; Abe, T.
10.1101/2020.03.17.995159 — neuroscience — Posted on 2020-03-17
2033 Comparative Pathogenesis Of COVID-19, MERS And SARS In A Non-Human Primate Model
Rockx, B.; Kuiken, T.; Herfst, S.; Bestebroer, T.; Lamers, M.; de Meulder, D.; van Amerongen, G.; van de Brand, J.; Okba, N.; Schipper, D.; van Run, P.; Leijten, L.; Verschoor, E.; Verstrepen, B.; Langermans, J.; Drosten, C.; Fentener van Vlissingen, M.; Fouchier, R.; de Swart, R. L.; Koopmans, M.; Haagmans, B.
10.1101/2020.03.17.995639 — microbiology — Posted on 2020-03-17
2034 Vaccine Elicitation of HIV Broadly Neutralizing Antibodies from Engineered B cells
Huang, D.; Tran, J. T.; Olson, A.; Vollbrecht, T.; Guryleva, M. V.; Tenuta, M.; Fuller, R. P.; Schiffner, T.; Abadejos, J. R.; Couvrette, L.; Blane, T. R.; Saye, K.; Li, W.; Landais, E.; Gonzalez-Martin, A.; Schief, W.; Murrell, B.; Burton, D. R.; Nemazee, D.; Voss, J. E.
10.1101/2020.03.17.989699 — immunology — Posted on 2020-03-17
2037 Effects of a blend of essential oils in milk replacer on performance, rumen fermentation, blood parameters and health scores of dairy heifers
Palhares Campolina, J.; Gesteira Coelhor, S.; Belli, A. L.; Samarini Machado, F.; R. Pereira, L. G.; R. Tomich, T.; A. Carvalho, W.; S. Silva, R. O.; L. Voorsluys, A.; V. Jacob, D.; Magalhaes Campos, M.
10.1101/2020.03.17.995209 — animal behavior and cognition — Posted on 2020-03-17
2039 Insulin dissociates by diverse mechanisms of coupled unfolding and unbinding
Antoszewski, A.; Feng, C.-J.; Vani, B.; Thiede, E. H.; Hong, L.; Weare, J.; Tokmakoff, A.; Dinner, A. R.
10.1101/2020.03.16.993931 — biophysics — Posted on 2020-03-17
2041 Stability and detection of nucleic acid from viruses and hosts in mosquito blood meals
Reddy, M. R.; Drummond, C.; Gebhardt, M. E.; Saenz Robles, M. T.; Carpi, G.; Hoyer, I.; Pastusiak, A.; Norris, D. E.; Pipas, J. M.; Jackson, E. K.
10.1101/2020.03.17.995126 — microbiology — Posted on 2020-03-17
2043 Single-cell transcriptomic analysis of the adult mouse spinal cord
Blum, J.; Nakayama, L.; Klemm, S.; Kathiria, A.; Guttenplan, K.; Hoang, P.; Shadrach, J.; Kaltschmidt, J.; Greenleaf, W.; Gitler, A. D.
10.1101/2020.03.16.992958 — neuroscience — Posted on 2020-03-17
2046 Accurate Diagnosis of Colorectal Cancer Based on Histopathology Images Using Artificial Intelligence
Wang, K.-S.; Yu, G.; Xu, C.; Meng, X.-H.; Zhou, J.; Zheng, C.; Deng, Z.; Shang, L.; Liu, R.; Su, S.; Zhou, X.; Li, Q.; Li, J.; Wang, J.; Ma, K.; Qi, J.; Hu, Z.; Tang, P.; Deng, J.; Qiu, X.; Li, B.-Y.; Shen, W.-D.; Quan, R.-P.; Yang, J.-T.; Huang, L.-Y.; Xiao, Y.; Yang, Z.-C.; Li, Z.; Wang, S.-C.; Ren, H.; Liang, C.; Guo, W.; Li, Y.; Xiao, H.; Gu, Y.; Yun, J.-P.; Huang, D.; Song, Z.; Fan, X.; Chen, L.; Yan, X.; Li, Z.; Huang, Z.-C.; Huang, J.; Luttrell, J.; Zhang, C.-Y.; Zhou, W.; Zhang, K.; Yi, C.; Shen, H.; Wang, Y.-P.; Xiao, H.; Deng, H.-W.
10.1101/2020.03.15.992917 — pathology — Posted on 2020-03-17
2048 Increased random exploration in schizophrenia is associated with inflammation
Cathomas, F.; Klaus, F.; Guetter, K.; Chung, H.-K.; Raja Beharelle, A.; Spiller, T.; Schlegel, R.; Seifritz, E.; Hartmann-Riemer, M.; Tobler, P. N.; Kaiser, S.
10.1101/2020.03.15.989483 — molecular biology — Posted on 2020-03-17
2049 Genome architecture and transcription data reveal allelic bias during the cell cycle
Lindsly, S. M.; Jia, W.; Chen, H.; Ronquist, S.; Chen, C.; Wen, X.; Li, S. C.; Wicha, M.; Rehemtulla, A.; Muir, L.; Rajapakse, I.
10.1101/2020.03.15.992164 — bioinformatics — Posted on 2020-03-17
2050 Quantitative prospective and retrospective mass spectrometry of lactoyl-CoA in mammalian cells and tissues
Varner, E. L.; Trefely, S.; Bartee, D.; von Krusenstiern, E.; Izzo, L.; Bekeova, C.; O'Connor, R. S.; Seifert, E. L.; Wellen, K.; Meier, J. L.; Snyder, N. W.
10.1101/2020.03.15.992859 — biochemistry — Posted on 2020-03-17
2051 Efficient inactivation of SARS-CoV-2 by WHO-recommended hand rub formulations and alcohols
Kratzel, A.; Todt, D.; V'kovski, P.; Steiner, S.; Gultom, M. L.; Thao, T. T. N.; Ebert, N.; Holwerda, M.; Steinmann, J.; Niemeyer, D.; Dijkman, R.; Kampf, G.; Drosten, C.; Steinmann, E.; Thiel, V.; Pfaender, S.
10.1101/2020.03.10.986711 — microbiology — Posted on 2020-03-17
2052 Detecting sample swaps in diverse NGS data types using linkage disequilibrium
Javed, N. M.; Farjoun, Y.; Fennell, T.; Epstein, C. B.; Bernstein, B. E.; Shoresh, N.
10.1101/2020.03.15.992750 — bioinformatics — Posted on 2020-03-17
2053 Population-wide Screening for Germline Variants of Hereditary Cancer Genes in 12K Unselected Japanese Colorectal Cancers and 27K Controls
Fujita, M.; Liu, X.; Iwasaki, Y.; Terao, C.; Takata, S.; Inai, C.; Aoi, T.; Maejima, K.; Hirata, M.; Murakami, Y.; Kamatani, Y.; Kubo, M.; Akagi, K.; Matsuda, K.; Nakagawa, H.; Momozawa, Y.
10.1101/2020.03.15.989947 — genetics — Posted on 2020-03-17
2054 MECHANISM OF ANTERIOR CRUCIATE LIGAMENT LOADING DURING DYNAMIC MOTOR TASKS
NASSERI, A.; Lloyd, D. G.; Bryant, A. L.; Headrick, J.; Sayer, T.; Saxby, D. J.
10.1101/2020.03.15.992370 — bioengineering — Posted on 2020-03-17
2059 Multimodal determinants of phase-locked dynamics across deep-superficial hippocampal sublayers during theta oscillations
Navas-Olive, A.; Valero, M.; Jurado-Parras, T.; de Salas-Quiroga, A.; Averkin, R. G.; Gambino, G.; Cid, E.; de la Prida, L. M.
10.1101/2020.03.15.991935 — neuroscience — Posted on 2020-03-17
2061 The Effect of Visual Uncertainty on Implicit Motor Adaptation
Tsay, J. S.; Avraham, G.; Kim, H. E.; Parvin, D. E.; Wang, Z.; Ivry, R. B.
10.1101/2020.03.15.992008 — neuroscience — Posted on 2020-03-17
2064 Multiple approaches for massively parallel sequencing of HCoV-19 genomes directly from clinical samples
Xiao, M.; Liu, X.; Ji, J.; Li, M.; Li, J.; Yang, L.; Sun, W.; Ren, P.; Yang, G.; Zhao, J.; Liang, T.; Ren, H.; Chen, T.; Zhong, H.; Song, W.; Wang, Y.; Deng, Z.; Zhao, Y.; Ou, Z.; Wang, D.; Cai, J.; Cheng, X.; Feng, T.; Wu, H.; Gong, Y.; Yang, H.; Wang, J.; Xu, X.; Zhu, S.; Chen, F.; Zhang, Y.; Chen, W.; Li, Y.; Li, J.
10.1101/2020.03.16.993584 — genomics — Posted on 2020-03-17
2065 Recapitulation of SARS-CoV-2 Infection and Cholangiocyte Damage with Human Liver Organoids
Zhao, B.; Ni, C.; Gao, R.; Wang, Y.; Yang, L.; Wei, J.; Lv, T.; Liang, J.; Zhang, Q.; Xu, W.; Xie, Y.; Wang, X.; Yuan, Z.; Liang, J.; Zhang, R.; Lin, X.
10.1101/2020.03.16.990317 — cell biology — Posted on 2020-03-17
2067 Bat coronavirus phylogeography in the western Indian Ocean
Joffrin, L.; Goodman, S. M.; Wilkinson, D. A.; Ramasindrazana, B.; Lagadec, E.; Gomard, Y.; Le Minter, G.; Dos Santos, A.; Schoeman, M. C.; Sookhareea, R.; Tortosa, P.; Julienne, S.; Gudo, E.; Mavingui, P.; Lebarbenchon, C.
10.1101/742866 — evolutionary biology — Posted on 2020-03-17
2071 A Cryptic Site of Vulnerability on the Receptor Binding Domain of the SARS-CoV-2 Spike Glycoprotein
Joyce, M. G.; Sankhala, R. S.; Chen, W.-H.; Choe, M.; Bai, H.; Hajduczki, A.; Yan, L.; Sterling, S. L.; Peterson, C.; Green, E. C.; Smith, C.; de Val, N.; Amare, M.; Scott, P.; Laing, E. D.; Broder, C. C.; Rolland, M.; Michael, N. L.; Modjarrad, K.
10.1101/2020.03.15.992883 — immunology — Posted on 2020-03-17
2072 Structure of RNA-dependent RNA polymerase from 2019-nCoV, a major antiviral drug target
Gao, Y.; Yan, L.; Huang, Y.; Liu, F.; Zhao, Y.; Cao, L.; Wang, T.; Sun, Q.; Ming, Z.; Zhang, L.; Ge, J.; Zheng, L.; Zhang, Y.; Wang, H.; Zhu, Y.; Zhu, C.; Hu, T.; Hua, T.; Zhang, B.; Yang, X.; Li, J.; Yang, H.; Liu, Z.; Xu, W.; Guddat, L. W.; Wang, Q.; Lou, Z.; Rao, Z.
10.1101/2020.03.16.993386 — biochemistry — Posted on 2020-03-17
2073 An emergent clade of SARS-CoV-2 linked to returned travellers from Iran
Eden, J.-S.; Rockett, R.; Carter, I.; Rahman, H.; de Ligt, J.; Hadfield, J.; Storey, M.; Ren, X.; Tulloch, R.; Basile, K.; Wells, J.; Byun, R.; Gliroy, N.; O'Sullivan, M. V.; Sintchenko, V.; Chen, S. C.; Maddocks, S.; Sorrell, T. C.; Holmes, E. C.; Dwyer, D. E.; Kok, J.
10.1101/2020.03.15.992818 — microbiology — Posted on 2020-03-17
2074 Cross-reactive antibody response between SARS-CoV-2 and SARS-CoV infections
Lv, H.; Wu, N. C.; Tsang, O. T.-Y.; Yuan, M.; Perera, R. A. P. M.; Leung, W. S.; So, R. T. Y.; Chan, J. M. C.; Yip, G. K.; Chik, T. S. H.; Wang, Y.; Choi, C. Y. C.; Lin, Y.; Ng, W. W.; Zhao, J.; Poon, L. L. M.; Peiris, J. S. M.; Wilson, I. A.; Mok, C. K. P.
10.1101/2020.03.15.993097 — microbiology — Posted on 2020-03-17
2078 Low variability of dynamical functional connectivity in cerebellar networks
Fernandez-Iriondo, I.; Jimenez-Marin, A.; Diez, I.; Bonifazi, P.; Swinnen, S. P.; Munoz, M. A.; Cortes, J.
10.1101/2020.03.16.989590 — neuroscience — Posted on 2020-03-17
2080 HiCanu: accurate assembly of segmental duplications, satellites, and allelic variants from high-fidelity long reads
Nurk, S.; Walenz, B. P.; Rhie, A.; Vollger, M. R.; Logsdon, G. A.; Grothe, R.; Miga, K. H.; Eichler, E. E.; Phillippy, A. M.; Koren, S.
10.1101/2020.03.14.992248 — bioinformatics — Posted on 2020-03-17
2084 Bacillus anthracis chain length, a virulence determinant, is regulated by a transmembrane Ser/Thr protein kinase PrkC
Gupta, M.; Singh, Y.; Dhasmana, N.; Kumar, N.; Gangwal, A.; keshavam, C. c.; Singh, L. K.; Sangwan, N.; nashier, P.; biswas, S.; Pomerantsev, A. P.; Leppla, S. H.
10.1101/2020.03.15.992834 — microbiology — Posted on 2020-03-17
2085 Functionally non-redundant paralogs spe-47 and spe-50 encode FB-MO associated proteins and interact with him-8
Clark, J. N.; Prajapati, G.; Aldaco, F. K.; Sokolich, T. J.; Keung, S. S.; Austin, S. P.; Valdes, A. A.; LaMunyon, C. W.
10.1101/2020.03.13.990366 — cell biology — Posted on 2020-03-17
2088 A bleb initiation model for chemotaxis suggests a role for myosin II clusters and cortex rupture
Asante-Asamani, E. O.; Grange, D.; Rawal, D.; Santiago, Z.; Loustau, J.; Brazill, D.
10.1101/2020.03.16.993238 — cell biology — Posted on 2020-03-17
2089 A dendritic-like microtubule network is organized from swellings of the basal fiber in neural progenitors
Coquand, L.; Victoria, G. S.; Tata, A.; Brault, J.-B.; Guimiot, F.; Fraisier, V.; Baffet, A. D.
10.1101/2020.03.16.993295 — cell biology — Posted on 2020-03-17
2092 Gain-of-function mutations amplify cytotoxic FAM111 protease activity in human genetic disorders
Hoffmann, S.; Pentakota, S.; Mund, A.; Haahr, P.; Coscia, F.; Gallo, M.; Mann, M.; Taylor, N. M. I.; Mailand, N.
10.1101/2020.03.16.993600 — cell biology — Posted on 2020-03-16
2095 Hypoxia-tolerant vascular endothelial growth factor-A (VEGF-A) and the genetic variations of VEGFA in Sherpa highlanders
Droma, Y.; Kinjo, T.; Nozawa, S.; Kobayashi, N.; Yasuo, M.; Kitaguchi, Y.; Ota, M.; Basnyat, B.; Hanaoka, M.
10.1101/2020.03.16.993568 — genetics — Posted on 2020-03-16
2096 Testing the efficacy of lionfish traps in the northern Gulf of Mexico
Harris, H. E.; Fogg, A. Q.; Gittings, S. R.; Ahrens, R. N. M.; Allen, M. S.; Patterson, W. F.
10.1101/2020.03.16.993543 — ecology — Posted on 2020-03-16
2099 Glycolytic metabolism of pathogenic T cells enables early detection of GvHD by 13C-MRI
Assmann, J. C.; Farthing, D. E.; Saito, K.; Maglakelidze, N.; Oliver, B.; Warrick, K. A.; Sourbier, C.; Ricketts, C. J.; Meyer, T. J.; Pavletic, S. Z.; Linehan, W. M.; Krishna, M. C.; Gress, R. E.; Buxbaum, N. P.
10.1101/2020.03.16.984609 — immunology — Posted on 2020-03-16
2103 Protein domain-based structural interfaces help interpret biologically-relevant interactions in the human interaction network.
Kilambi, K. P.; Xu, Q.; Kuthethur Gururaj, G.; Li, K.; Artavanis-Tsakonas, S.; Dunbrack, R. L.; Lehmann, A.
10.1101/2020.03.14.992149 — systems biology — Posted on 2020-03-16
2104 Multiplex single-molecule kinetics of nanopore-coupled polymerases
Palla, M.; Punthambaker, S.; Stranges, P. B.; Vigneault, F.; Nivala, J.; Wiegand, D. J.; Ayer, A.; Craig, T.; Gremyachinskiy, D.; Franklin, H.; Sun, S.; Pollard, J.; Trans, A.; Arnold, C.; Schwab, C.; Mcgaw, C.; Sarvabhowman, P.; Dalal, D.; Thai, E.; Amato, E.; Lederman, I.; Taing, M.; Kelley, S.; Qwan, A.; Fuller, C. W.; Roever, S.; Church, G. M.
10.1101/2020.03.15.993071 — synthetic biology — Posted on 2020-03-16
2105 Differential TAM receptor regulation of hepatic physiology and injury
Lemke, G. E.; Zagorska, A.; Traves, P. G.; Jimenez-Garcia, L.; Strickland, J. D.; Tapia, F. J.; Mayoral Monibas, R.; Burrola, P.; Copple, B. L.
10.1101/2020.03.13.990143 — physiology — Posted on 2020-03-16
2106 Autism-linked gene FoxP1 selectively regulates the cultural transmission of learned vocalizations
Garcia-Oscos, F.; Koch, T.; Pancholi, H.; Trusel, M.; Daliparthi, V.; Ayhan, F.; Co, M.; Alam, D. H.; Holdway, J. E.; Konopka, G.; Roberts, T. F.
10.1101/2020.03.14.992016 — neuroscience — Posted on 2020-03-16
2107 Learning to Control the Brain through Adaptive Closed-Loop Patterned Stimulation
Tafazoli, S.; MacDowell, C. J.; Che, Z.; Letai, K. C.; Steinhardt, C.; Buschman, T. J.
10.1101/2020.03.14.992198 — neuroscience — Posted on 2020-03-16
2110 Discrimination among Cryptococcus deneoformans, C. neoformans and interspecies hybrids using MALDI-TOF Mass Spectrometry
Zvezdanova, M. E.; Arroyo, M. J.; Mendez, G.; Guinea, J.; Mancera, L.; Munoz, P.; Rodriguez-Sanchez, B.; Escribano, P.
10.1101/2020.03.13.991661 — microbiology — Posted on 2020-03-16
2113 Fermented food metagenomics reveals substrate-associated differences in taxonomy, health-associated- and antibiotic resistance-determinants
Leech, J.; Cabrera-Rubio, R.; Walsh, A. M.; Macori, G.; Walsh, C. J.; Barton, W.; Finnegan, L.; Crispie, F.; O'Sullivan, O.; Claesson, M. J.; Cotter, P. D.
10.1101/2020.03.13.991653 — microbiology — Posted on 2020-03-16
2115 Targeting CXCR1 and CXCR2 to overcome radiotherapy resistance in PTEN-deficient prostate carcinoma
Armstrong, C. W. D.; Coulter, J. A.; Ong, C. W.; Maxwell, P. J.; Walker, S.; Butterworth, K. T.; Lyubomska, O.; Berlingeri, S.; Gallagher, R.; O'Sullivan, J. M.; Jain, S.; Mills, I. G.; Prise, K. M.; Bristow, R. G.; LaBonte, M. J.; Waugh, D. J. J.
10.1101/2020.03.16.993394 — cancer biology — Posted on 2020-03-16
2116 Dissection of prostate tumour, stroma and immune transcription reveals a key contribution by the microenvironment to disease progression
Mangiola, S.; McCoy, P.; Modrak, M.; Guimaraes, F. S. F.; Blashki, D.; Stuchbery, R.; Kerger, M.; Chow, K.; Nasa, C.; Le Page, M.; Lister, N.; Monard, S.; Peters, J.; Dundee, P.; Costello, A. J.; Pal, B.; Huntington, N. D.; Corcoran, N.; Papenfuss, A. T.; Hovens, C. M.
10.1101/2020.03.16.993162 — cancer biology — Posted on 2020-03-16
2117 RRE-Finder: A Genome-Mining Tool for Class-Independent RiPP Discovery
Kloosterman, A. M.; Shelton, K. E.; van Wezel, G.; Medema, M. H.; Mitchell, D. A.
10.1101/2020.03.14.992123 — bioinformatics — Posted on 2020-03-16
2119 A novel neural stem cell-derived immunocompetent mouse model of glioblastoma for preclinical studies
Costa, B.; Fletcher, M. N.; Boskovic, P.; Ivanova, E. L.; Eisemann, T.; Lohr, S.; Bunse, L.; Loewer, M.; Burchard, S.; Korshunov, A.; Liu, H.-K.; Platten, M.; Radlwimmer, B.; Angel, P.; Peterziel, H.
10.1101/2020.03.16.993196 — cancer biology — Posted on 2020-03-16
2120 Expression of Toll like Receptor 4 in the ductal epithelial cells of the Breast tumor microenvironment is correlated with the invasiveness of the tumor
MOIRANGTHEM, A.; MUKHERJEE, M.; BANDYOPADHYAY, B.; BONDHOPADHYAY, A.; MUKHERJEE, N.; KONAR, K.; Das, T.; DUTTA, P.; BASU, A.
10.1101/2020.03.15.993014 — cancer biology — Posted on 2020-03-16
2122 Asymmetric chromosome segregation and cell division in DNA damage-induced bacterial filaments
Raghunathan, S.; Chimthanawala, A.; Krishna, S.; Vecchiarelli, A.; Badrinarayanan, A.
10.1101/2020.03.16.993485 — microbiology — Posted on 2020-03-16
2124 Sex determining gene transposition as an evolutionary platform for chromosome turnover
Ayllon, F.; Solberg, M. F.; Besnier, F.; Fjelldal, P. G.; Hansen, T. J.; Edvarsen, R. B.; Wargelius, A.; Glover, K. A.
10.1101/2020.03.14.991026 — genetics — Posted on 2020-03-16
2125 De-novo purine biosynthesis is a major driver of chemoresistance in glioblastoma
Shireman, J. M.; Atashi, F.; Lee, G.; Ali, E.; Saathoff, M.; Park, C.; Baiswala, S.; Miska, J.; Lesniak, M.; David, J. C.; Stupp, R.; Kumthekar, P.; Horbinski, C.; Ben-Sahar, I.; Ahmed, A. U.
10.1101/2020.03.13.991125 — cancer biology — Posted on 2020-03-16
2126 Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules
Nabet, B.; Ferguson, F. M.; Seong, B. K. A.; Kuljanin, M.; Leggett, A. L.; Mohardt, M. L.; Robichaud, A.; Conway, A. S.; Buckley, D. L.; Mancias, J. D.; Bradner, J. E.; Stegmaier, K.; Gray, N. S.
10.1101/2020.03.13.980946 — cancer biology — Posted on 2020-03-16
2128 SNAPflex: a paper-and-plastic device for instrument-free RNA and DNA extraction from whole blood
Kolluri, N.; Albarran, N.; Fan, A.; Olson, A.; Sagar, M.; Young, A.; Gomez-Marquez, J.; Klapperich, C. M.
10.1101/2020.03.14.991893 — bioengineering — Posted on 2020-03-16
2129 Forensic microbial system for high-resolution object provenance
Qian, J.; Lu, Z.-x.; Mancuso, C. P.; Jhuang, H.-Y.; Barajas-Ornelas, R. d. C.; Boswell, S.; Ramirez-Guadiana, F. H.; Jones, V.; Sonti, A.; Sedlack, K.; Artzi, L.; Jung, G.; Arammash, M.; Melfi, M.; Lyon, L.; Owen, S. V.; Baym, M.; Khalil, A. S.; Silver, P. A.; Rudner, D.; Springer, M.
10.1101/2020.03.14.990804 — bioengineering — Posted on 2020-03-16
2131 Locus coeruleus MRI contrast is associated with cortical thickness in older adults
Bachman, S. L.; Dahl, M. J.; Werkle-Bergner, M.; Duezel, S.; Forlim, C. G.; Lindenberger, U.; Kuehn, S.; Mather, M.
10.1101/2020.03.14.991596 — neuroscience — Posted on 2020-03-16
2136 Directed Evolution of Adenine Base Editors with Increased Activity and Therapeutic Application
Gaudelli, N.; Lam, D. K.; Rees, H. A.; Sola-Esteves, N. M.; Barrera, L. A.; Born, D. A.; Edwards, A.; Gehrke, J. M.; Lee, S.-J.; Liquori, A. J.; Murray, R.; Packer, M. S.; Rinaldi, C.; Slaymaker, I. M.; Yen, J.; Young, L. E.; Ciaramella, G.
10.1101/2020.03.13.990630 — genomics — Posted on 2020-03-16
2137 CHD8 Suppression Impacts on Histone H3 Lysine 36 Trimethylation and Alters RNA Alternative Splicing.
Kerschbamer, E.; Tripathi, T.; Erdin, S.; Salviato, E.; Di Leva, F.; Sebestyen, E.; Arnoldi, M.; Benelli, M.; Gusella, J. F.; Piazza, S.; Demichelis, F.; Talkowski, M. E.; Ferrari, F.; Biagioli, M.
10.1101/2020.03.14.992032 — genetics — Posted on 2020-03-16
2140 Menthol in Electronic Cigarettes: A Contributor to Respiratory Disease?
Nair, V.; Tran, M.; Behar, R. Z.; Zhai, S.; Cui, X.; Phandthong, R.; Wang, Y.; Pan, S.; Luo, W.; Pankow, J. F.; Volz, D. C.; Talbot, P.
10.1101/2020.03.14.988006 — cell biology — Posted on 2020-03-16
2144 Two antagonistic effect genes mediate separation of sexes in a fully dioecious plant
Xue, L.; Wu, H.; Chen, Y.; Li, X.; Hou, J.; Lu, J.; Wei, S.; Dai, X.; Olson, M. S.; Liu, J.; Wang, M.; Charlesworth, D.; Yin, T.
10.1101/2020.03.15.993022 — plant biology — Posted on 2020-03-16
2145 NOSA, an analytical toolbox for multicellular optical electrophysiology
Oltmanns, S.; Abben, F. S.; Ender, A.; Aimon, S.; Kovacs, R.; Sigrist, S. J.; Storace, D. A.; Geiger, J. R. P.; Raccuglia, D.
10.1101/2020.03.15.992420 — neuroscience — Posted on 2020-03-16
2155 Oxytocin differentially modulates amygdala responses during top-down and bottom-up aversive anticipation
Xin, F.; Zhou, X.; Dong, D.; Zhao, Z.; Yang, X.; Wang, Q.; Gu, Y.; Kendrick, K. M.; Chen, A.; Becker, B.
10.1101/2020.03.14.992172 — neuroscience — Posted on 2020-03-16
2164 LZTR1 inactivation promotes MAPK/ ERK pathway activation in glioblastoma by stabilizing oncoprotein RIT1
Wang, Y.; Zhang, J.; Zhang, P.; Zhao, Z.; Huang, Q.; Yun, D.; Chen, J.; Chen, H.; Wang, C.; Lu, D.
10.1101/2020.03.14.989954 — cancer biology — Posted on 2020-03-15
2165 JNK signaling regulates oviposition in the malaria vector Anopheles gambiae
Peirce, M. J.; Mitchell, S. N.; Kakani, E. G.; Scarpelli, P.; South, A.; Shaw, W. R.; Werling, K. L.; Gabrieli, P.; Marcenac, P.; Bordoni, M.; Talesa, V. N.; Catteruccia, F.
10.1101/2020.03.14.990945 — animal behavior and cognition — Posted on 2020-03-15
2166 Development of A Novel Highly Selective TLR8 Agonist for Cancer Immunotherapy
Wang, Y.; Yang, H.; Li, H.; Zhao, S.; Zeng, Y.; Zhang, P.; Lin, X.; Sun, X.; Wang, L.; Fu, G.; Gao, Y.; Wang, P.; Gao, D.
10.1101/2020.03.14.991760 — pharmacology and toxicology — Posted on 2020-03-15
2168 Biochemical computation underlying behavioral decision-making
Thornquist, S. C.; Pitsch, M. J.; Auth, C. S.; Crickmore, M. A.
10.1101/2020.03.14.992057 — neuroscience — Posted on 2020-03-15
2170 Connexin 43 hemichannels mediate spatial and temporal disease spread in ALS
Almad, A. A.; Taga, A.; Joseph, J.; Welsh, C.; Patankar, A.; Gross, S. K.; Richard, J.-P.; Pokharel, A.; Lillo, M.; Dastgheyb, R.; Eggan, K.; Haughey, N.; Contreras, J. E.; Maragakis, N. J.
10.1101/2020.03.14.990747 — neuroscience — Posted on 2020-03-15
2172 Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning & reduces neurodegeneration
Ryan, V. H.; Perdikari, T. M.; Naik, M. T.; Saueressig, C. F.; Lins, J.; Dignon, G. L.; Mittal, J.; Hart, A. C.; Fawzi, N. L.
10.1101/2020.03.15.992768 — biochemistry — Posted on 2020-03-15
2176 Adaptive evolution of DNA methylation reshaped gene regulation in maize
Xu, G.; Lyu, J.; Li, Q.; Liu, H.; Wang, D.; Zhang, M.; Springer, N. M.; Ross-Ibarra, J.; Yang, J.
10.1101/2020.03.13.991117 — plant biology — Posted on 2020-03-15
2178 Greater male than female variability in regional brain structure across the lifespan
Wierenga, L. M.; Doucet, G. E.; Dima, D.; Agartz, I.; Aghajani, M.; Akudjedu, T. N.; Albajes-Eizagirre, A.; Alnaes, D.; Alpert, K. I.; Andreassen, O. A.; Anticevic, A.; Asherson, P.; Banaschewski, T.; Bargallo, N.; Baumeister, S.; Baur-Streubel, R.; Bertolino, A.; Bonvino, A.; Boomsma, D. I.; Borgwardt, S.; Bourque, J.; den Braber, A.; Brandeis, D.; Breier, A.; Brodaty, H.; Brouwer, R. M.; Buitelaar, J. K.; Busatto, G. F.; Calhoun, V. D.; Canales-Rodriguez, E. J.; Cannon, D.; Caseras, X.; Chaim-Avancini, T.; Castellanos, F. X.; Chaim-Avancini, T. M.; Ching, C. R.; Clark, V. P.; Conrod, P. J.;
10.1101/2020.02.17.952010 — neuroscience — Posted on 2020-03-15
2180 Rapid speciation of cichlids fishes may be explained by evolutionary divergence of novel open reading frames
Puntambekar, S.; Newhouse, R.; Navas, J. S. M.; Chauhan, R.; Vernaz, G.; Willis, T.; Wayland, M. T.; Urmania, Y.; Miska, E. A.; Prabakaran, S.
10.1101/2020.03.13.991182 — evolutionary biology — Posted on 2020-03-15
2181 Gli3 utilizes Hand2 to synergistically regulate tissue-specific transcriptional networks
Elliott, K. H.; Chen, X.; Salomone, J.; Chatuverdi, P.; Schultz, P. A.; Balchand, S. K.; Servetas, J. D.; Zuniga, A.; Zeller, R.; Gebelein, B.; Weirauch, M. T.; Peterson, K. A.; Brugmann, S. A.
10.1101/2020.03.13.990481 — developmental biology — Posted on 2020-03-15
2182 Lipid availability influences the metabolic maturation of human pluripotent stem cell-derived cardiomyocytes
Zhang, H.; Badur, M. G.; Spiering, S.; Divakaruni, A.; Meurs, N. E.; Yu, M. S.; Colas, A. R.; Murphy, A. N.; Mercola, M.; Metallo, C. M.
10.1101/2020.03.14.991927 — cell biology — Posted on 2020-03-15
2183 A conformational switch driven by phosphorylation regulates Ykt6 activity in macroautophagy
McGrath, K.; Dergai, M.; Agarwal, S.; Chung, D.; van Rossum, D. B.; Shevade, A.; Kuchin, S.; Zaichick, S.; Savas, J. N.; Fasshauer, D.; Caraveo, G.
10.1101/2020.03.15.992727 — cell biology — Posted on 2020-03-15
2185 Structural and developmental principles of neuropil assembly in C. elegans
Moyle, M. W.; Barnes, K. M.; Kuchroo, M.; Gonopolskiy, A.; Duncan, L. H.; Sengupta, T.; Shao, L.; Guo, M.; Santella, A.; Christensen, R.; Kumar, A.; Wu, Y.; Moon, K. R.; Wolf, G.; Krishnaswamy, S.; Bao, Z.; Shroff, H.; Mohler, W.; Colon-Ramos, D. A.
10.1101/2020.03.15.992222 — neuroscience — Posted on 2020-03-15
2186 Differentiation of human intestinal organoids with endogenous vascular endothelial cells
Holloway, E. M.; Wu, J. H.; Czerwinski, M.; Sweet, C. W.; Wu, A.; Tsai, Y.-H.; Huang, S.; Stoddard, A. E.; Capeline, M. M.; Glass, I.; Spence, J.
10.1101/2020.03.15.991950 — developmental biology — Posted on 2020-03-15
2189 Distinctive Gene and Protein Characteristics of Extremely Piezophilic Colwellia
Peoples, L. M.; Kyaw, T. S.; Ugalde, J. U.; Mullane, K. K.; Chastain, R. A.; Yayanos, A. A.; Kusube, M.; Methe, B. A.; Bartlett, D. H.
10.1101/2020.03.15.992594 — microbiology — Posted on 2020-03-15
2195 A novel HER2-targeted antibody-drug conjugate offers the possibility of clinical dosing at trastuzumab-equivalent exposure levels
Barfield, R. M.; Kim, Y. C.; Chuprakov, S.; Zhang, F.; Bauzon, M.; Ogunkoya, A. O.; Yeo, D.; Hickle, C.; Pegram, M. D.; Rabuka, D.; Drake, P. M.
10.1101/2020.03.13.991448 — pharmacology and toxicology — Posted on 2020-03-15
2196 Injectable Nanoelectrodes Enable Wireless Deep Brain Stimulation of Native Tissue in Freely Moving Mice
Kozielski, K. L.; Jahanshahi, A.; Gilbert, H. B.; Yu, Y.; Erin, O.; Francisco, D.; Alosaimi, F.; Temel, Y.; Sitti, M.
10.1101/2020.03.14.978676 — bioengineering — Posted on 2020-03-15
2198 Genetic disruption of the Blood Brain Barrier leads to protective barrier formation at the Glia Limitans
Hollier, P. L.; Guimbal, S.; Mora, P.; Diop, A.; Cornuault, L.; Couffinhal, T.; Gadeau, A. P.; Renault, M.-A.; Chapouly, C.
10.1101/2020.03.13.990762 — neuroscience — Posted on 2020-03-15
2200 The dorsal striatum sets the sensitivity to effort
Jurado-Parras, M.-T.; Safaie, M.; Sarno, S.; Louis, J.; Karoutchi, C.; Berret, B.; Robbe, D.
10.1101/2020.03.13.991000 — neuroscience — Posted on 2020-03-15
2202 Evidence for face selectivity in early vision
Campana, F.; Martin, J. G.; Bokeria, L.; Thorpe, S.; Jiang, X.; Riesenhuber, M.
10.1101/2020.03.14.987735 — neuroscience — Posted on 2020-03-15
2204 Human dorsal anterior cingulate neurons signal conflict by amplifying task-relevant information
Ebitz, B.; Smith, E.; Horga, G.; Schevon, C.; Yates, M.; McKhann, G.; Botvinick, M.; Sheth, S.; Hayden, B.
10.1101/2020.03.14.991745 — neuroscience — Posted on 2020-03-15
2206 Elucidating the pathogenic mechanisms of AD brain-derived tau-containing extracellular vesicles: Highly transmissible and preferential propagation to GABAergic neurons
Ruan, Z.; Pathak, D.; Kalavai, S. V.; Yoshii-Kitahara, A.; Muraoka, S.; Takamatsu-Yukawa, K.; Hu, J.; Wang, Y.; Hersh, S.; Gorantla, S.; Kayed, R.; Gendelman, H.; Ikezu, S.; Luebke, J. I.; Ikezu, T.
10.1101/2020.03.15.992719 — neuroscience — Posted on 2020-03-15
2207 psiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation
Strittmatter, L. M.; Capitanchik, C.; Newman, A. J.; Hallegger, M.; Norman, C. M.; Fica, S. M.; Oubridge, C.; Luscombe, N. M.; Ule, J.; Nagai, K.
10.1101/2020.03.15.992701 — molecular biology — Posted on 2020-03-15
2208 Rapidly predicting vancomycin resistance of Enterococcus faecium through MALDI-TOF MS spectra obtained in real-world clinical microbiology laboratory
Wang, H.-Y.; Lu, K.-P.; Chung, C.-R.; Tseng, Y.-J.; Lee, T.-Y.; Chang, T.-H.; Wu, M.-H.; Lin, T.-W.; Liu, T.-P.; Lu, J.-J.
10.1101/2020.03.13.990978 — microbiology — Posted on 2020-03-15
2209 A 2,000-year-old specimen with intraerythrocytic Bartonella quintana
Barbieri, R.; Mai, H. A. B.; Chenal, T.; Bassi, M.-L.; Gandia, D.; Camoin-Jau, L.; Lepidi, H.; Aboudharam, G.; Drancourt, M.
10.1101/2020.03.13.990580 — microbiology — Posted on 2020-03-15
2213 Five millennia of Bartonella quintana bacteremia.
Mai, H. A. B.; Barbieri, R.; Chenal, T.; Castex, D.; Jonvel, R.; Tanasi, D.; George-Zimmerman, P.; Dutour, O.; Drancourt, M.; Aboudharam, G.
10.1101/2020.03.13.990796 — microbiology — Posted on 2020-03-15
2214 Whole slide imaging to understand Candida biofilm growth and response to antifungals
Raas, M. W. D.; Silva, T. P.; Freitas, J. O. C.; Campos, L. M.; Fabri, R. L.; Melo, R. C.
10.1101/2020.03.15.992735 — microbiology — Posted on 2020-03-15
2216 ATM-deficient lung, prostate and pancreatic cancer cells are acutely sensitive to the combination of olaparib and the ATR inhibitor AZD6738
Jette, N. R.; Radhamani, S.; Ye, R.; Yu, Y.; Arthur, G.; Goutam, S.; Bizmar, T.; Kumar, M.; Bose, P.; Yip, S.; Kolinsky, M.; Lees-MIller, S. P.
10.1101/2020.03.13.991166 — cancer biology — Posted on 2020-03-15
2219 Structure of a Single Chain H2A/H2B Dimer
Warren, C.; Bonanno, J. B.; Almo, S. C.; Shechter, D.
10.1101/2020.03.15.992685 — biochemistry — Posted on 2020-03-15
2223 Synthesis of Glycoconjugates Utilizing the Regioselectivity of a Lytic Polysaccharide Monooxygenase
Westereng, B.; Kracun, S. K.; Leivers, S.; Arntzen, M.; Aachmann, F. L.; Eijsink, V. G. H.
10.1101/2020.03.13.990838 — biochemistry — Posted on 2020-03-15
2224 Efficient Generation of Isogenic Primary Human Myeloid Cells using CRISPR-Cas9 Ribonucleoproteins
Hiatt, J.; Cavero, D. A.; McGregor, M. J.; Gordon, D. E.; Zheng, W.; Budzik, J. M.; Roth, T. L.; Haas, K. M.; Rathore, U.; Meyer-Franke, A.; Bouzidi, M. S.; Hultquist, J. F.; Wojcechowskyj, J. A.; Fontaine, K. A.; Pillai, S. K.; Cox, J. S.; Ernst, J. D.; Krogan, N. J.; Marson, A.
10.1101/2020.03.13.991414 — genetics — Posted on 2020-03-15
2226 The maturity in fetal pigs using a multi-fluid metabolomic approach
Lefort, G.; Servien, R.; Quesnel, H.; Billon, Y.; Canario, L.; Iannuccelli, N.; Canlet, C.; Paris, A.; Vialaneix, N.; Liaubet, L.
10.1101/2020.03.13.990564 — developmental biology — Posted on 2020-03-15
2228 Human-derived NLS enhance the gene transfer efficiency of chitosan
Bitoque, D. B.; Morais, J.; Oliveira, A. V.; Sequeira, R. L.; Calado, S. M.; Fortunato, T. M.; Simao, S.; Rosa da Costa, A. M.; Silva, G. A.
10.1101/2020.03.13.990390 — bioengineering — Posted on 2020-03-15
2229 Decoding mRNA translatability and stability from 5'UTR
Jia, L.; Mao, Y.; Ji, Q.; Dersh, D.; Yewdell, J. W.; Qian, S.-B.
10.1101/2020.03.13.990887 — biochemistry — Posted on 2020-03-15
2230 In-depth characterization of Staurosporine induced proteome thermal stability changes
Chernobrovkin, A. L.; Lengqvist, J.; Cacares Korner, C.; Amadio, D.; Friman, T.; Molina, D. M.
10.1101/2020.03.13.990606 — molecular biology — Posted on 2020-03-15
2231 Human iPSC-based neurodevelopmental models of globoid cell leukodystrophy uncover patient- and cell type-specific disease phenotypes
Mangiameli, E.; Cecchele, A.; Morena, F.; Sanvito, F.; Matafora, V.; Della Volpe, L.; Gnani, D.; Paulis, M.; Susani, L.; Martino, S.; Di Micco, R.; Bachi, A.; Gritti, A.
10.1101/2020.03.13.990176 — genetics — Posted on 2020-03-15
2232 Reducing ecological complexity using the archetype approach - an application to natural pest control
Alexandridis, N.; Martin, E. A.; Marion, G.; Chaplin-Kramer, R.; Dainese, M.; Ekroos, J.; Grab, H.; Jonsson, M.; Karp, D. S.; Meyer, C.; O'Rourke, M. E.; Pontarp, M.; Poveda, K.; Seppelt, R.; Smith, H. G.; Clough, Y.
10.1101/2020.03.13.990531 — ecology — Posted on 2020-03-15
2233 Facets of individual-specific health signatures determined from longitudinal plasma proteome profiling
Dodig-Crnkovic, T.; Hong, M.-G.; Engel Thomas, C.; Häussler, R. S.; Bendes, A.; Dale, M.; Edfors, F.; Forsström, B.; Magnusson, P. K.; Schuppe-Koistinen, I.; Odeberg, J.; Fagerberg, L.; Gummesson, A.; Bergström, G.; Uhlen, M.; Schwenk, J.
10.1101/2020.03.13.988683 — biochemistry — Posted on 2020-03-15
2237 HflX controls hypoxia-induced non-replicating persistence in slow growing mycobacteria
NGAN, J. Y. G.; PASUNOOTI, S.; TSE, W.; MENG, W.; NGAN, S. F. C.; NG, S. W.; JAAFAR, M. T.; JIA, H.; CHO, S. L. S.; LIM, J.; KOH, H. Q. V.; ABDULGHANI, N.; PETHE, K.; Sze, K. S.; Lescar, J.; Alonso, S.
10.1101/2020.03.13.990168 — microbiology — Posted on 2020-03-15
2238 Evolution of genome structure in the Drosophila simulans species complex
Chakraborty, M.; Chang, C.-H.; Khost, D.; Vedanayagam, J.; Adrion, J. R.; Liao, Y.; Montooth, K. L.; Meiklejohn, C. D.; Larracuente, A. M.; Emerson, J. J.
10.1101/2020.02.27.968743 — genomics — Posted on 2020-03-15
2240 Self-antigen driven affinity maturation is required for pathogenic monovalent IgG4 autoantibody development
Fichtner, M. L.; Vieni, C.; Redler, R.; Kolich, L.; Jiang, R.; Takata, K.; Stathopoulos, P.; Suarez, P.; Nowak, R. J.; Burden, S. J.; Ekiert, D.; O'Connor, K. C.
10.1101/2020.03.14.988758 — immunology — Posted on 2020-03-15
2241 ATM-mediated DNA damage response in macrophages primes phagocytosis and immune checkpoint regulation
Bansal, A.; Neuhaus, R.; Izquierdo-Alvarez, E.; Nolte, H.; Vorholt, D.; Feldkoetter, H.; Lohneis, P.; Buettner, R.; Krueger, M.; Pallasch, C.; Schumacher, B.
10.1101/2020.03.14.987438 — immunology — Posted on 2020-03-15
2242 Dynamic changes in tRNA modifications and abundance during T-cell activation
Rak, R.; Polonsky, M.; Eizenberg, I.; Dahan, O.; Friedman, N.; Pilpel, Y. T.
10.1101/2020.03.14.991901 — genomics — Posted on 2020-03-15
2244 Unravelling the phylogenomic relationships of the most diverse African palm genus Raphia (Calamoideae, Arecaceae)
Helmstetter, A. J.; Mogue Kamga, S.; Bethune, K.; Lautenschläeger, T.; Zizka, A.; Bacon, C. D.; Wieringa, J. J.; Stauffer, F.; Antonelli, A.; Sonke, B.; Couvreur, T. L. P.
10.1101/2020.03.09.984351 — plant biology — Posted on 2020-03-15
2247 The architecture of SARS-CoV-2 transcriptome
Kim, D.; Lee, J.-Y.; Yang, J.-S.; Kim, J. W.; Kim, V. N.; Chang, H.
10.1101/2020.03.12.988865 — genomics — Posted on 2020-03-15
2249 High photon count rates improve the quality of super-resolution fluorescence fluctuation spectroscopy
Schneider, F.; Hernandez-Varas, P.; Lagerholm, B. C.; Shrestha, D.; Sezgin, E.; Roberti, J.; Ossato, G.; Hecht, F.; Eggeling, C.; Urbancic, I.
10.1101/783639 — biophysics — Posted on 2020-03-15
2250 Magnetoelectric materials for miniature, wireless neural stimulation at therapeutic frequencies
Singer, A.; Dutta, S.; Lewis, E.; Chen, Z.; Chen, J. C.; Verma, N.; Avants, B.; Feldman, A. K.; O'Malley, J.; Beierlein, M.; Kemere, C.; Robinson, J. T.
10.1101/461855 — bioengineering — Posted on 2020-03-15
2252 Peripheral Nerve Repair Using Tissue Engineered Living Scaffolds Comprised of Stretch-Grown Aligned Axonal Tracts Promotes Survival of Spinal Cord Motor Neurons
Maggiore, J. C.; Burrell, J. C.; Browne, K. D.; Katiyar, K. C.; Laimo, F. A.; Ali, Z.; Kaplan, H. M.; Rosen, J. M.; Cullen, D. K.
10.1101/847988 — bioengineering — Posted on 2020-03-15
2263 A molecular map of lymph node blood vascular endothelium at single cell resolution
Brulois, K.; Rajaraman, A.; Szade, A.; Nordling, S.; Bogoslowski, A.; Dermadi, D.; Rahman, M.; Kiefel, H.; O'Hara, E.; Koning, J. J.; Kawashima, H.; Zhou, B.; Vestweber, D.; Red-Horse, K.; Mebius, R.; Adams, R. H.; Kubes, P.; Pan, J.; Butcher, E. C.
10.1101/2020.03.13.991604 — immunology — Posted on 2020-03-14
2264 RNA sequencing reveals interacting key determinants of osteoarthritis acting in subchondral bone and articular cartilage.
Tuerlings, M.; van Hoolwerff, M.; Houtman, E.; Suchiman, E. H. E. D.; Lakenberg, N.; Mei, H.; van der Linden, E. H. M. J.; Nelissen, R. R. G. H. H.; Ramos, Y. Y. F. M.; de Almeida, R.; Meulenbelt, I.
10.1101/2020.03.13.969386 — genomics — Posted on 2020-03-14
2266 Mapping the influence of the gut microbiota on small molecules in the brain through mass spectrometry imaging
Wall, D. M.; Hulme, H.; Meikle, L. M.; Strittmatter, N.; Swales, J.; Hamm, G.; Brown, S. L.; Milling, S.; MacDonald, A. S.; Goodwin, R. J.; Burchmore, R.
10.1101/2020.03.13.987164 — microbiology — Posted on 2020-03-14
2269 The COMPASS-like complex modulates fungal development and pathogenesis by regulating H3K4me3-mediated targeted gene expression in Magnaporthe oryzae
wang, w.; zhou, s.; sun, w.; zhang, m.; yin, y.; pan, s.; zhao, x.; xu, y.; he, d.; shen, m.; yang, j.; liu, x.; zheng, q.
10.1101/2020.03.13.990218 — microbiology — Posted on 2020-03-14
2271 Genome-wide Screens Identify Lineage- and Tumor Specific-Genes Modulating MHC-I and MHC-II Immunosurveillance in Human Lymphomas
Dersh, D.; Phelan, J. D.; Gumina, M. E.; Wang, B.; Arbuckle, J. H.; Holly, J.; Kishton, R. J.; Markowitz, T. E.; Seedhom, M. O.; Fridlyand, N.; Wright, G. W.; Huang, D. W.; Ceribelli, M.; Thomas, C. J.; Lack, J. B.; Restifo, N. P.; Kristie, T. M.; Staudt, L. M.; Yewdell, J. W.
10.1101/2020.03.13.989558 — cancer biology — Posted on 2020-03-14
2272 Detection of M-Protein in Acetonitrile Precipitates of Serum using MALDI-TOF Mass Spectrometry
Mehra, N.; Gopisetty, G.; Subramani, J.; Rajamanickam, A.; Sundersingh, S.; Karunakaran, P.; Perumal Kalaiyarasi, J.; Kannan, K.; Radhakrishnan, V.; Tenali Gnana, S.; Thangarajan, R.
10.1101/2020.03.13.990192 — biochemistry — Posted on 2020-03-14
2275 Cytoplasmic incompatibility between Old and New World populations of a tramp ant
Ün, C.; Schultner, E.; Manzano-Marin, A.; Florez, L. V.; Seifert, B.; Heinze, J.; Oettler, J.
10.1101/2020.03.13.988675 — evolutionary biology — Posted on 2020-03-14
2276 Discovery of the world's highest-dwelling mammal
Storz, J. F.; Quiroga-Carmona, M.; Opazo, J. C.; Bowen, T.; Farson, M.; D'Elia, G.
10.1101/2020.03.13.989822 — evolutionary biology — Posted on 2020-03-14
2277 Large-scale Proteomic and Phosphoproteomic Analysis of Maize Seedling Leaves During De-etiolation
Gao, Z.-f.; Shen, Z.; Chao, Q.; Yan, Z.; Ge, X.-L.; Lu, T.; Zheng, H.; Qian, C.-R.; Wang, B.-c.
10.1101/2020.03.13.977843 — bioinformatics — Posted on 2020-03-14
2278 Differential responses of transplanted stem cells to the diseased environment unveiled by a single molecular NIR II cell tracker
Chen, H.; Yang, H.; Zhang, C.; Chen, S.; Zhao, X.; Zhu, M.; Wang, Z.; Zhang, X.; Wang, Y.; Wo, H.-t.; Li, K.; Cheng, Z.
10.1101/2020.03.12.988295 — bioengineering — Posted on 2020-03-14
2280 Different Proteins Mediate Step-wise Chromosome Architectures in Thermoplasma acidophilum and Pyrobaculum calidifontis
Maruyama, H.; Prieto, E. I.; Nambu, T.; Mashimo, C.; Kashiwagi, K.; Okinaga, T.; Atomi, H.; Takeyasu, K.
10.1101/2020.03.13.982959 — microbiology — Posted on 2020-03-14
2282 A Clock-Driven Neural Network Critical for Arousal
Bell, B. J.; Liu, Q.; Kim, D. W.; Lee, S. S.; Liu, Q.; Blum, I. D.; Wang, A.; Bedont, J. L.; Chang, A.; Issa, H.; Cohen, J. Y.; Blackshaw, S.; Wu, M. N.
10.1101/2020.03.12.989921 — neuroscience — Posted on 2020-03-14
2283 Purging of deleterious mutations during domestication in the predominant selfing crop soybean
Kim, M.-S.; Lozano, R.; Kim, J. H.; Bae, D. N.; Kim, S.-T.; Park, J.-H.; Choi, M. S.; Kim, J.; Ok, H. C.; Park, S.-K.; Gore, M. A.; Moon, J. K.; Jeong, S.-C.
10.1101/2020.03.12.989830 — genomics — Posted on 2020-03-14
2286 Differential encoding in prefrontal cortex projection neuron classes across cognitive tasks
Lui, J. H.; Nguyen, N. D.; Grutzner, S. M.; Darmanis, S.; Peixoto, D.; Wagner, M. J.; Allen, W. E.; Kebschull, J. M.; Richman, E. B.; Ren, J.; Newsome, W. T.; Quake, S. R.; Luo, L.
10.1101/2020.03.14.991018 — neuroscience — Posted on 2020-03-14
2289 CRISPR-TRAPSeq identifies the QKI RNA binding protein as important for astrocytic maturation and control of thalamocortical synapses.
Sakers, K.; Liu, Y.; Llaci, L.; Vasek, M. J.; Rieger, M. A.; Brophy, S. a.; Tycksen, E.; Lewis, R.; Maloney, S. E.; Dougherty, J.
10.1101/2020.03.13.991224 — neuroscience — Posted on 2020-03-14
2290 Sensitive spatial genome wide expression profiling at cellular resolution
Stickels, R. R.; Murray, E.; Kumar, P.; Li, J.; Marshall, J. L.; Di Bella, D.; Arlotta, P.; Macosko, E. Z.; Chen, F.
10.1101/2020.03.12.989806 — genomics — Posted on 2020-03-14
2291 Scalable method for micro-CT analysis enables large scale quantitative characterization of brain lesions and implants
Kastner, D. B.; Kharazia, V.; Nevers, R.; Astudillo Maya, D.; Williams, G. M.; Yang, Z.; Smyth, C.; Della Santina, L.; Parkinson, D. Y.; Frank, L. M.
10.1101/2020.03.12.989871 — neuroscience — Posted on 2020-03-14
2292 Global shortfalls in extinction risk assessments for endemic flora
Gallagher, R. V.; Allen, S.; Rivers, M.; Allen, A.; Butt, N.; Keith, D.; Auld, T. D.; Enquist, B. J.; Wright, I. J.; Possingham, H. P.; Espinosa-Ruiz, S.; Dimitrova, N.; Mifsud, J. C.; Adams, V. M.
10.1101/2020.03.12.984559 — ecology — Posted on 2020-03-14
2293 Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma
Zah, E.; Nam, E.; Bhuvan, V.; Tran, V. T. T.; Ji, B. Y.; Gosliner, S. B.; Wang, X.; Brown, C. E.; Chen, Y. Y.
10.1101/2020.03.12.989491 — bioengineering — Posted on 2020-03-14
2294 Establishing cell-intrinsic limitations in cell cycle progression controls graft growth and promotes differentiation of pancreatic endocrine cells
Sui, L.; Egli, D. M.; Xin, Y.; Georgieva, D. C.; Diedenhofen, G.; Haataja, L.; Su, Q.; Wang, Y.; Zuccaro, M.; Kim, J.; Fu, J.; Xing, Y.; Baum, D.; Arvan, P.; Barbetti, F.; Kleiner, S.; Oberholzer, J.; Goland, R.
10.1101/2020.03.13.990812 — cell biology — Posted on 2020-03-14
2295 Cholinergic basal forebrain degeneration due to obstructive sleep apnoeaincreases Alzheimer's pathology in mice
Qian, L.; Kasas, L.; Milne, M. M.; Rawashdeh, O.; Marks, N.; Sharma, A.; Bellingham, M. C.; Coulson, E. J.
10.1101/2020.03.12.989848 — neuroscience — Posted on 2020-03-14
2296 Selective gating of retinal information by arousal
Liang, L.; Fratzl, A.; El Mansour, O.; Reggiani, J. D. S.; Chen, C.; Andermann, M. L.
10.1101/2020.03.12.989913 — neuroscience — Posted on 2020-03-14
2297 Parallel social information processing circuits are differentially impacted in autism
Lewis, E. M.; Stein-O'Brien, G.; Patino, A.; Nardou, R.; Grossman, C. D.; Brown, M.; Bangamwabo, B.; Ndiaye, N.; Giovinazzo, D.; Dardani, I.; Jiang, C.; Goff, L.; Dolen, G.
10.1101/2020.03.13.990549 — neuroscience — Posted on 2020-03-14
2301 Signaling input from divergent pathways subverts malignant B-cell transformation
Chan, L. N.; Murakami, M. A.; Robinson, M. E.; Caeser, R.; Sadras, T.; Lee, J.; Cosgun, K. N.; Kume, K.; Khairnar, V.; Xiao, G.; Ahmed, M.; Aghania, E.; Deb, G.; Hurtz, C.; Shojaee, S.; Hong, C.; Polonen, P.; Nix, M. A.; Chen, Z.; Chen, C. W.; Chen, J.; Vogt, A.; Heinaniemi, M.; Lohi, O.; Wiita, A. P.; Izraeli, S.; Geng, H.; Weinstock, D. M.; Muschen, M.
10.1101/2020.03.12.989749 — cancer biology — Posted on 2020-03-14
2302 Analysis procedures for assessing recovery of high quality, complete, closed genomes from Nanopore long read metagenome sequencing
Arumugam, K.; Bessarab, I.; Haryono, M. A. S.; Liu, X.; Zuniga-Montanez, R. E.; Roy, S.; Qiu, G.; Moses, D. I.; Law, Y.; Wuertz, S.; Lauro, F. M.; Huson, D.; Williams, R. B. H.
10.1101/2020.03.12.974238 — bioinformatics — Posted on 2020-03-14
2304 Rhesus macaques can be effectively infected with SARS-CoV-2 via ocular conjunctival route
Deng, W.; Bao, L.; Gao, H.; Xiang, Z.; Qu, Y.; Song, Z.; Gong, S.; Liu, J.; Liu, J.; Yu, P.; Qi, F.; Xu, Y.; Li, F.; Xiao, C.; Lv, Q.; Xue, J.; Wei, Q.; Liu, M.; Wang, G.; Wang, S.; Yu, H.; Liu, X.; Zhao, W.; Han, Y.; Qin, C.
10.1101/2020.03.13.990036 — microbiology — Posted on 2020-03-14
2306 Nucleotide Analogues as Inhibitors of SARS-CoV Polymerase
Ju, J.; Li, X.; Kumar, S.; Jockusch, S.; Chien, M.; Tao, C.; Morozova, I.; Kalachikov, S.; Kirchdoerfer, R.; Russo, J. J.
10.1101/2020.03.12.989186 — pharmacology and toxicology — Posted on 2020-03-14
2307 SARS-CoV-2 invades host cells via a novel route: CD147-spike protein
Wang, K.; Chen, W.; Zhou, Y.-S.; Lian, J.-Q.; Zhang, Z.; Du, P.; Gong, L.; Zhang, Y.; Cui, H.-Y.; Geng, J.-J.; Wang, B.; Sun, X.-X.; Wang, C.-F.; Yang, X.; Lin, P.; Deng, Y.-Q.; Wei, D.; Yang, X.-M.; Zhu, Y.-M.; Zhang, K.; Zheng, Z.-H.; Miao, J.-L.; Guo, T.; Shi, Y.; Zhang, J.; Fu, L.; Wang, Q.-Y.; Bian, H.; Zhu, P.; Chen, Z.-N.
10.1101/2020.03.14.988345 — microbiology — Posted on 2020-03-14
2308 Development of CRISPR as a prophylactic strategy to combat novel coronavirus and influenza
Abbott, T. R.; Dhamdhere, G.; Liu, Y.; Lin, X.; Goudy, L. E.; Zeng, L.; Chemparathy, A.; Chmura, S.; Heaton, N.; Debs, R.; Pande, T.; Endy, D.; La Russa, M.; Lewis, D. B.; Qi, L. S.
10.1101/2020.03.13.991307 — bioengineering — Posted on 2020-03-14
2309 SARS-CoV-2 receptor ACE2 and TMPRSS2 are predominantly expressed in a transient secretory cell type in subsegmental bronchial branches
Lukassen, S.; Chua, R. L.; Trefzer, T.; Kahn, N. C.; Schneider, M. A.; Muley, T.; Winter, H.; Meister, M.; Veith, C.; Boots, A. W.; Hennig, B. P.; Kreuter, M.; Conrad, C.; Eils, R.
10.1101/2020.03.13.991455 — genomics — Posted on 2020-03-14
2310 Accurate Identification of SARS-CoV-2 from Viral Genome Sequences using Deep Learning
Lopez-Rincon, A.; Tonda, A.; Mendoza-Maldonado, L.; Claassen, E.; Garssen, J.; Kraneveld, A. D.
10.1101/2020.03.13.990242 — bioinformatics — Posted on 2020-03-14
2311 A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV
Yuan, M.; Wu, N. C.; Zhu, X.; Lee, C.-C. D.; So, R. T. Y.; Lv, H.; Mok, C. K. P.; Wilson, I. A.
10.1101/2020.03.13.991570 — microbiology — Posted on 2020-03-14
2312 The architecture of SARS-CoV-2 transcriptome
Kim, D.; Lee, J.-Y.; Yang, J.-S.; Kim, J. W.; Kim, V. N.; Chang, H.
10.1101/2020.03.12.988865 — genomics — Posted on 2020-03-14
2314 Endothelial mTOR maintains hematopoiesis during aging
Ramalingam, P.; Poulos, M. G.; Gutkin, M. C.; Katsnelson, L.; Freire, A. S.; Lazzari, E.; Butler, J. M.
10.1101/2020.03.13.990911 — cell biology — Posted on 2020-03-14
2315 Tales of 1,008 Small Molecules: Phenomic Profiling through Live-cell Imaging in a Panel of Reporter Cell Lines
Cox, M. J.; Jaensch, S.; Van de Waeter, J.; Cougnaud, L.; Seynaeve, D.; Benalla, S.; Koo, S. J.; Van Den Wyngaert, I.; Neefs, J.-M.; Malkov, D.; Bittremieux, M.; Steemans, M.; Peeters, P. J.; Wegner, J. K.; Ceulemans, H.; Gustin, E.; Chong, Y. T.; Göhlmann, H. W. H.
10.1101/2020.03.13.990093 — pharmacology and toxicology — Posted on 2020-03-14
2317 Flexibility and constraint in preimplantation gene regulation in mouse
Conine, C.; Krykbaeva, M.; Song, L.; Brewster, R.; Friedman, N.; Rando, O.
10.1101/2020.03.13.990275 — developmental biology — Posted on 2020-03-14
2318 AGO HITS-CLIP in Adipose Tissue Reveals miR-29 as a Post-Transcriptional Regulator of Leptin
O'Connor, S.; Murphy, E.; Szwed, S. K.; Kanke, M.; Marchildon, F.; Darnell, R. B.; Sethupathy, P.; Cohen, P.
10.1101/2020.03.13.991422 — cell biology — Posted on 2020-03-14
2322 Architecture and subunit dynamics of the mitochondrial TIM9·10·12 chaperone
Weinhäupl, K.; Wang, Y.; Hessel, A.; Brennich, M.; Lindorff-Larsen, K.; Schanda, P.
10.1101/2020.03.13.990150 — biophysics — Posted on 2020-03-14
2325 Reinfection could not occur in SARS-CoV-2 infected rhesus macaques
Bao, L.; Deng, W.; Gao, H.; Xiao, C.; Liu, J.; Xue, J.; Lv, Q.; Liu, J.; Yu, P.; Xu, Y.; Qi, F.; Qu, Y.; Li, F.; Xiang, Z.; Yu, H.; Gong, S.; Liu, M.; Wang, G.; Wang, S.; Song, Z.; Zhao, W.; Han, Y.; Zhao, L.; Liu, X.; Wei, Q.; Qin, C.
10.1101/2020.03.13.990226 — microbiology — Posted on 2020-03-14
2326 High sensitivity detection of SARS-CoV-2 using multiplex PCR and a multiplex-PCR-based metagenomic method
Li, C.; Debruyne, D.; Spencer, J.; Kapoor, V.; Liu, L. Y.; Zhang, B.; Lee, L.; Feigelman, R.; Burdon, G.; Liu, J.; Oliva, A.; Borcherding, A.; Xu, J.; Urban, A. E.; Liu, G.; Liu, Z.
10.1101/2020.03.12.988246 — genomics — Posted on 2020-03-14
2327 Identification of a molecular fingerprint for synaptic glia
Castro, R.; Taetzsch, T.; Vaughan, S.; Godbe, K.; Settlage, R.; Chappell, J.; Valdez, G.
10.1101/2020.03.13.991323 — neuroscience — Posted on 2020-03-14
2328 Metabolic life tables: the sockeye salmon example
Burger, J. R.; Hou, C.; Hall, C. A. S.; Brown, J. H.
10.1101/2020.03.13.990986 — ecology — Posted on 2020-03-14
2329 Rapid Fractionation and Characterisation of Alpha-Synuclein Oligomers in Solution
Arter, W. E.; Xu, C. K.; Castellana-Cruz, M.; Herling, T. W.; Krainer, G.; Saar, K. L.; Kumita, J. R.; Dobson, C. M.; Knowles, T. P.
10.1101/2020.03.10.985804 — biophysics — Posted on 2020-03-14
2330 GABAergic neurons and Nav1.1 channel hyperactivity: a novel neocortex-specific mechanism of cortical spreading depression.
Chever, O.; Zerimech, S.; Scalmani, P.; Lemaire, L.; Loucif, A.; Ayrault, M.; Krupa, M.; Desroches, M.; Duprat, F.; Cestele, S.; Mantegazza, M.
10.1101/2020.03.14.991158 — neuroscience — Posted on 2020-03-14
2333 IRF8 Governs Tumor-Associated Macrophage Control of T Cell Exhaustion
Nixon, B.; Kuo, F.; Liu, M.; Capistrano, K.; Do, M.; Franklin, R.; Wu, X.; Kansler, E.; Srivastava, R.; Purohit, T.; Sanchez, A.; Vuong, L.; Krishna, C.; Morse, H.; Hsieh, J.; Chan, T.; Murphy, K.; Moon, J.; Hakimi, A.; Li, M.
10.1101/2020.03.12.989731 — immunology — Posted on 2020-03-14
2334 Content and performance of the MiniMUGA genotyping array, a new tool to improve rigor and reproducibility in mouse research
Sigmon, J. S.; Blanchard, M.; Baric, R. S.; Bell, T. A.; Brennan, J.; Brockmann, G. A.; Burks, A. W.; Calabrese, M.; Caron, K. M.; Cheney, R. E.; Ciavatta, D.; Conlon, F.; Darr, D. B.; Faber, J.; Franklin, C.; Gershon, T. R.; Gralinski, L. E.; Gu, B.; Gaines, C. H.; Hagan, R. S.; Heimsath, E. G.; Heise, M. T.; Hock, P.; Ideraabdullah, F.; Jennette, J. C.; Kafri, T.; Kashfeen, A.; Kelada, S. N. P.; Kulis, M.; Kumar, V.; Linnertz, C. L.; Livraghi-Butrico, A.; Lloyd, K.; Loeser, R.; Lutz, C. M.; Lynch, R. M.; Magnuson, T.; Matsushima, G. K.; McMullan, R.; Miller, D.; Mohlke, K. L.; Moy, S. S.; Mu
10.1101/2020.03.12.989400 — genetics — Posted on 2020-03-14
2335 β-catenin Signaling Regulates Cell Fate Decisions at the Transition Zone of the Chondro-Osseous Junction During Fracture Healing
Wong, S. A.; Hu, D.; Shao, T.; Niemi, E.; Barruet, E.; Morales, B. M.; Boozarpour, O.; Miclau, T.; Hsiao, E. C.; Nakamura, M.; Bahney, C. S.; Marcucio, R.
10.1101/2020.03.11.986141 — developmental biology — Posted on 2020-03-14
2337 Targeting OCA-B/Pou2af1 blocks type-1 diabetes and reduces infiltration of activated, islet-reactive T cells
Kim, H.; Perovanovic, J.; Shakya, A.; Shen, Z.; German, C. N.; Ibarra, A.; Jafek, J. L.; Lin, N.-P.; Evavold, B. D.; Chou, D. H.- C.; Jensen, P. E.; He, X.; Tantin, D.
10.1101/2020.02.06.937839 — immunology — Posted on 2020-03-14
2338 Fast and flexible design of novel proteins using graph neural networks
Strokach, A.; Becerra, D.; Corbi-Verge, C.; Perez-Riba, A.; Kim, P. M.
10.1101/868935 — bioinformatics — Posted on 2020-03-14
2339 On generative models of T-cell receptor sequences
Isacchini, G.; Sethna, Z.; Elhanati, Y.; Nourmohammad, A.; Walczak, A. M.; Mora, T.
10.1101/857722 — immunology — Posted on 2020-03-14
2342 Perceptual detection depends on spike count integration
Cone, J. J.; Bade, M. L.; Masse, N. Y.; Page, E. A.; Freedman, D. J.; Maunsell, J. H.
10.1101/865410 — neuroscience — Posted on 2020-03-14
2344 Standardization and Harmonization of Distributed Multi-National Proteotype Analysis supporting Precision Medicine Studies
Xuan, Y.; Bateman, N. W.; Gallien, S.; Goetze, S.; Zhou, Y.; Navarro, P.; Hu, M.; Parikh, N.; Hood, B. L.; Conrads, K. A.; Loosse, C.; Kitata, R. B.; Piersma, S. R.; Chiasserini, D.; Zhu, H.; Hou, G.; Tahir, M.; Macklin, A.; Khoo, A.; Sun, X.; Crossett, B.; Sickmann, A.; Chen, Y.-J.; Jimenez, C. R.; Zhou, H.; Liu, S.; Larsen, M. R.; Kislinger, T.; Chen, Z.; Parker, B. L.; Cordwell, S. J.; Wollscheid, B.; Conrads, T. P.
10.1101/2020.03.12.988089 — molecular biology — Posted on 2020-03-14
2349 Changing the Waddington landscape to control mesendoderm competence
Valcourt, J. R.; Huang, R.; Kundu, S.; Venkatasubramanian, D.; Kingston, R. E.; Ramanathan, S.
10.1101/867010 — developmental biology — Posted on 2020-03-14
2351 A Gaussian process model of human electrocorticographic data
Owen, L. L. W.; Muntianu, T. A.; Heusser, A. C.; Daly, P.; Scangos, K. W.; Manning, J. R.
10.1101/121020 — neuroscience — Posted on 2020-03-14
2353 What is AIDS in the Amazon and the Guianas in the 90-90-90 era?
Nacher, M.; Adenis, A.; Guarmit, B.; Lucarelli, A.; Blanchet, D.; Demar, M.; Djossou, F.; Abboud, P.; Epelboin, L.; Couppie, P.
10.1101/2020.03.13.990473 — microbiology — Posted on 2020-03-13
2355 Malaria in Southern Venezuela: The Hottest Hotspot in Latin America
Grillet, M. E.; Moreno, J. E.; Hernandez, J. V.; Vincenti-Gonzalez, M. F.; Noya, O.; Tami, A.; Paniz-Mondolfi, A.; Llewellyn, M.; Lowe, R.; Escalante, A. A.; Conn, J. E.
10.1101/2020.03.13.990457 — ecology — Posted on 2020-03-13
2361 Dopamine D1 receptor signalling in dyskinetic Parkinsonian rats revealed by fiber photometry using FRET-based biosensors
Jones-Tabah, J.; Mohammad, H.; Hadj-Youssef, S.; Kim, L. E. H.; Martin, R. D.; Benaliouad, F.; Tanny, J. C.; Clarke, P. B. S.; Hebert, T. E.
10.1101/2020.03.12.989103 — neuroscience — Posted on 2020-03-13
2362 Hypoxic response regulators RHY-1 and EGL-9/PHD promote longevity through a VHL-1 independent transcriptional response.
Kruempel, J.; Miller, H.; Schaller, M. L.; Fretz, A.; Howington, M.; Sarker, M.; Huang, S.; Leiser, S.
10.1101/2020.03.12.989061 — genetics — Posted on 2020-03-13
2364 Global impact of phosphorylation on protein endurance
Wu, C.; Ba, Q.; Li, W.; Salovska, B.; Hou, P.; Mueller, T.; Rosenberger, G.; Gao, E.; Di, Y.; Liu, Y.
10.1101/2020.03.12.989467 — systems biology — Posted on 2020-03-13
2366 Tumor Necrosis Factor Receptor Signaling Modulates Carcinogenesis in a Mouse Model of Breast Cancer
He, L.; Bhat, K.; Duhacheck-Muggy, S.; Ioannidis, A.; Zhang, L.; Nguyen, N. T.; Moatamed, N. A.; Pajonk, F.
10.1101/2020.03.12.989335 — cancer biology — Posted on 2020-03-13
2369 Pten and Dicer1 loss causes poorly-differentiated endometrial adenocarcinoma in mice
Wang, X.; Wendel, J.; Emerson, R. E.; Broaddus, R. R.; Creighton, C. J.; Rusch, D.; Buechlein, A. M.; DeMayo, F. J.; Lydon, J. P.; Hawkins, S.
10.1101/2020.03.12.989087 — cancer biology — Posted on 2020-03-13
2370 A 'one-two punch' therapy strategy to target chemoresistance in ER+ breast cancer
Chi, F.; Liu, J.; Brady, S. W.; Cosgrove, P. A.; Nath, A.; McQuerry, J. A.; Majumdar, S.; Moos, P. J.; Chang, J. T.; Kahn, M.; Bild, A. H.
10.1101/2020.03.12.989251 — cancer biology — Posted on 2020-03-13
2374 Multi-Channel Whole-Head OPM-MEG: Helmet Design and a Comparison with a Conventional System
Hill, R. M.; Boto, E.; Rea, M.; Holmes, N.; Leggett, J.; Coles, L. A.; Papastavrou, M.; Everton, S.; Hunt, B.; Sims, D.; Osborne, J.; Shah, V.; Bowtell, R.; Brookes, M. J.
10.1101/2020.03.12.989129 — neuroscience — Posted on 2020-03-13
2375 An inability to maintain the ribonucleoprotein genomic structure is responsible for host detection of negative-sense RNA viruses
Blanco-Melo, D.; Nilsson-Payant, B. E.; Uhl, S.; Escudero, B.; Olschewski, S.; Thibault, P.; Panis, M.; Rosenthal, M.; Munoz-Fontela, C.; Lee, B.; tenOever, B.
10.1101/2020.03.12.989319 — microbiology — Posted on 2020-03-13
2376 A high-coverage Neandertal genome from Chagyrskaya Cave
Mafessoni, F.; Grote, S.; de Filippo, C.; Slon, V.; Kolobova, K. A.; Viola, B.; Markin, S.; Chintalapati, M.; Peyregne, S.; Skov, L.; Skoglund, P.; Krivoshapkin, A. I.; Derevianko, A. P.; Meyer, M.; Kelso, J.; Peter, B.; Prüfer, K.; Pääbo, S.
10.1101/2020.03.12.988956 — genomics — Posted on 2020-03-13
2377 Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome
Shaashua, L.; Eckerling, A.; Israeli, B.; Yanovich, G.; Rosenne, E.; Fichman-Horn, S.; Ben Zvi, I.; Sorski, L.; Satchi-Fainaro, R.; Geiger, T.; Sloan, E. K.; Ben-Eliyahu, S.
10.1101/2020.03.12.986992 — cancer biology — Posted on 2020-03-13
2378 Lipogenesis and innate immunity in hepatocellular carcinoma cells reprogrammed by an isoenzyme switch of hexokinases
Perrin-Cocon, L.; Vidalain, P.-O.; Jacquemin, C.; Aublin-Gex, A.; Olmstead, K.; Panthu, B.; Rautureau, G. J. P.; Andre, P.; Nyczka, P.; Hutt, M.-T.; Amoedo, N.; Rossignol, R.; Filipp, F. V.; Lotteau, V.; Diaz, O.
10.1101/2020.03.13.973321 — cancer biology — Posted on 2020-03-13
2379 Mutant p53 suppresses innate immune signaling to promote tumorigenesis
Ghosh, M.; Saha, S.; Bettke, J. A.; Nagar, R.; Parrales, A.; Iwakuma, T.; van der Velden, A. W. M.; Martinez, L. A.
10.1101/2020.03.12.989384 — cancer biology — Posted on 2020-03-13
2380 Lgr5-mediated restraint of β-catenin is essential for B-lymphopoiesis and leukemia-initiation
Cosgun, K. N.; Robinson, M. E.; Deb, G.; Yang, X.; Xiao, G.; Sadras, T.; Lee, J.; Chan, L. N.; Kume, K.; Winchester, J.; Chen, Z.; Yang, L.; Mueschen, M.
10.1101/2020.03.12.989277 — cancer biology — Posted on 2020-03-13
2382 The biomedical sensor Cell-Fit-HD4D, reveals individual tumor cell fate in response to microscopic ion deposition.
Niklas, M.; Schlegel, J.; Liew, H.; Walsh, D.; Zimmermann, F.; Dzyubachyk, O.; Holland-Letz, T.; Rahmanian, S.; Greilich, S.; Runz, A.; Debus, J.; Abdollahi, A.
10.1101/2020.03.12.987347 — cancer biology — Posted on 2020-03-13
2383 Carbon ion dosimetry on a fluorescent nuclear track detector using widefield microscopy
Walsh, D. W. M.; Liew, H.; Schlegel, J.; Mairani, A.; Abdollahi, A.; Niklas, M.
10.1101/2020.03.13.990325 — biophysics — Posted on 2020-03-13
2384 Microampere electric currents caused bacterial membrane damage and two-way leakage in short time
Krishnamurthi, V. R.; Rogers, A.; Peifer, J.; Niyonshuti, I. I.; Chen, J.; Wang, Y.
10.1101/2020.03.13.991067 — biophysics — Posted on 2020-03-13
2385 Anomalous Diffusion Characterization by Fourier-Transform FRAP with Patterned Illumination
Geiger, A. C.; Smith, C. J.; Takanti, N.; Harmon, D. M.; Carlsen, M. S.; Simpson, G. J.
10.1101/2020.03.13.990937 — biophysics — Posted on 2020-03-13
2386 Sexual dimorphism in the meiotic requirement for PRDM9: a mammalian evolutionary safeguard
Powers, N. R.; Dumont, B.; Emori, C.; Lawal, R. A.; Brunton, C.; Paigen, K.; Handel, M. A.; Bolcun-Filas, E. A.; Petkov, P. M.; Bhattacharyya, T.
10.1101/2020.03.10.985358 — genetics — Posted on 2020-03-13
2390 Synchronised oscillations in growing cell populations are explained by demographic noise
Gavagnin, E.; Vittadello, S. T.; Guanasingh, G.; Haass, N. K.; Simpson, M. J.; Rogers, T.; Yates, C. A.
10.1101/2020.03.13.987032 — cell biology — Posted on 2020-03-13
2393 Characterizing the Human Heart Rate Circadian Pacemaker through Widely Available Wearable Devices
Bowman, C.; Huang, Y.; Walch, O. J.; Fang, Y.; Frank, E.; Goldstein, C.; Sen, S.; Forger, D. B.
10.1101/2020.03.12.988899 — systems biology — Posted on 2020-03-13
2395 Glycolysis Fuels Phosphoinositide 3-Kinase Signaling to Bolster T Cell Immunity
Xu, K.; Yin, N.; Peng, M.; Stamatiades, E.; Shyu, A.; Li, P.; Zhang, X.; Do, M.; Wang, Z.; Capistrano, K.; Chou, C.; Levine, A.; Rudensky, A.; Li, M.
10.1101/2020.03.12.989707 — immunology — Posted on 2020-03-13
2397 Cell proliferation and migration explain pore bridging dynamics in 3D printed scaffolds of different pore size
Buenzli, P. R.; Lanaro, M.; Wong, C. S.; McLaughlin, M. P.; Allenby, M. C.; Woodruff, M. A.; Simpson, M. J.
10.1101/2020.03.12.989053 — bioengineering — Posted on 2020-03-13
2398 RhoBAST - A Rhodamine-Binding Aptamer for Super-Resolution RNA Imaging
Sunbul, M.; Lackner, J.; Martin, A.; Englert, D.; Hacene, B.; Nienhaus, K.; Nienhaus, G. U.; Jäschke, A.
10.1101/2020.03.12.988782 — cell biology — Posted on 2020-03-13
2399 Molecular resolution imaging by post-labeling expansion single molecule localization microscopy (Ex-SMLM)
Zwettler, F. U.; Reinhard, S.; Gambarotto, D.; Bell, T. D. M.; Hamel, V.; Guichard, P.; Sauer, M.
10.1101/2020.03.12.988923 — biophysics — Posted on 2020-03-13
2400 Establishment of a pig influenza challenge model for evaluation of monoclonal antibody delivery platforms
McNee, A.; Smith, T.; Holzer, B.; Becky, C.; Bessell, E.; Guibinga, G.; Brown, H.; Schultheis, K.; Fisher, P.; Ramos, S.; Nunez, A.; Bernard, M.; Martini, V.; Chrun, T.; Xiao, Y.; Kash, J. C.; Taubenberger, J. K.; Elliott, S.; Patel, A.; Beverley, P.; Rijal, P.; Weiner, D.; Townsend, A.; Broderick, K.; Tchilian, E.
10.1101/2020.03.12.988808 — immunology — Posted on 2020-03-13
2401 Biological activity of Ajuga iva extracts against the African cotton leafworm Spodoptera littoralis
Taha-Salaime, L.; Lebedev, G.; Abo-Nassar, J.; Marzouk, S.; Inbar, M.; Ghanim, M.; Aly, R.
10.1101/2020.03.12.988428 — plant biology — Posted on 2020-03-13
2403 Remyelination alters the pattern of myelin in the cerebral cortex
Orthmann-Murphy, J.; Call, C. L.; Molina-Castro, G. C.; Hsieh, Y. C.; Rasband, M. N.; Calabresi, P. A.; Bergles, D. E.
10.1101/2020.03.09.983569 — neuroscience — Posted on 2020-03-13
2404 Long-term synaptic depression triggers local biogenesis of autophagic vesicles in dendrites and requires autophagic degradation
Kallergi, E.; Daskalaki, A. D.; Ioannou, E.; Kolaxi, A.; Plataki, M.; Haberkant, P.; Stein, F.; Savitski, M. M.; Sidiropoulou, K.; Dalezios, Y.; Nikoletopoulou, V.
10.1101/2020.03.12.983965 — neuroscience — Posted on 2020-03-13
2405 Impaired adult hippocampal neurogenesis in Alzheimer's disease is mediated by microRNA-132 deficiency and can be restored by microRNA-132 replacement
Salta, E.; Walgrave, H.; Balusu, S.; Vanden Eynden, E.; Snoeck, S.; Craessaerts, K.; Thrupp, N.; Wolfs, L.; Horre, K.; Fourne, Y.; Ronisz, A.; Silajdzic, E.; Callaerts-Vegh, Z.; D Hooge, R.; Thal, D. R.; Zetterberg, H.; Thuret, S.; Fiers, M.; Sala Frigerio, C.; De Strooper, B.
10.1101/2020.03.12.988709 — neuroscience — Posted on 2020-03-13
2406 Perceived ambiguity of social interactions increases coupling between frontal and temporal nodes of the social brain
Ainsworth, M.; Sallet, J.; Joly, O.; Kriegeskorte, N.; Duncan, J.; Schüffelgen, U.; Rushworth, M. F.; Bell, A. H.
10.1101/2020.03.11.987792 — neuroscience — Posted on 2020-03-13
2407 Non-Negative Data-Driven Mapping of Structural Connections in the Neonatal Brain
Thompson, E.; Mohammadi-Nejad, A. R.; Robinson, E. C.; Glasser, M. F.; Jbabdi, S.; Bastiani, M.; Sotiropoulos, S. N.
10.1101/2020.03.09.965079 — neuroscience — Posted on 2020-03-13
2408 Rab27b regulates the release, autophagic clearance, and toxicity of alpha-synuclein
Underwood, R.; Wang, B.; Carico, C.; Whitaker, R. H.; Placzek, W. J.; Yacoubian, T.
10.1101/2020.03.09.984096 — neuroscience — Posted on 2020-03-13
2410 CRISPR-Csy4-mediated editing of rotavirus double-stranded RNA genome
Papa, G.; Venditti, L.; Braga, L.; Schneider, E.; Giacca, M.; Petris, G.; Burrone, O. R.
10.1101/2020.03.09.983262 — microbiology — Posted on 2020-03-13
2411 Powerful detection of polygenic selection and environmental adaptation in US beef cattle populations
Rowan, T. N.; Durbin, H. J.; Nilson, S. M.; Seabury, C. M.; Schnabel, R. D.; Decker, J. E.
10.1101/2020.03.11.988121 — genomics — Posted on 2020-03-13
2412 Major stages of vertebrate adaptive radiation are assembled from a disparate spatiotemporal landscape
Richards, E. J.; McGirr, J. A.; Wang, J.; St John, M. E.; Poelstra, J. W.; Solano, M. J.; O'Connell, D. C.; Turner, B. J.; Martin, C. H.
10.1101/2020.03.12.988774 — evolutionary biology — Posted on 2020-03-13
2413 LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium
Zwiggelaar, R.; Lindholm, H.; Fosslie, M.; Pedersen, M. T.; Ohta, Y.; Diez-Sanchez, A.; Martin-Alonso, M.; Ostrop, J.; Matano, M.; Parmar, N.; Kvaloy, E.; Spanjers, R.; Nazmi, K.; Rye, M. B.; Drablos, F.; Arrowsmith, C.; Dahl, J. A.; Jensen, K. B.; Sato, T.; Oudhoff, M. J.
10.1101/2020.02.20.958363 — developmental biology — Posted on 2020-03-13
2416 A dual-mechanism antibiotic targets Gram-negative bacteria and avoids drug resistance
Martin, J. K.; Wilson, M. Z.; Moore, G. M.; Sheehan, J. P.; Mateus, A.; Li, S. H.-J.; Bratton, B. P.; Kim, H.; Rabinowitz, J. D.; Typas, A.; Savitski, M. M.; Gitai, Z.
10.1101/2020.03.12.984229 — microbiology — Posted on 2020-03-13
2418 Exact mapping of Illumina blind spots in the Mycobacterium tuberculosis genome reveals platform-wide and workflow-specific biases
Modlin, S. J.; Robinhold, C.; Morrissey, C.; Mitchell, S. N.; Ramirez-Busby, S. M.; Shmaya, T.; Valafar, F.
10.1101/2020.03.11.987933 — bioinformatics — Posted on 2020-03-13
2421 Magnetotactic bacteria accumulate a large pool of iron distinct from their magnetite crystals
Amor, M.; Ceballos, A.; Wan, J.; Simon, C. P.; Aron, A. T.; Chang, C.; Hellman, F.; Komeili, A.
10.1101/2020.03.10.986679 — microbiology — Posted on 2020-03-13
2424 A transcriptomic continuum of differentiation arrest identifies myeloid interface acute leukemias with poor prognosis
Bond, J.; Krzywon, A.; Lhermitte, L.; Roumier, C.; Roggy, A.; Belhocine, M.; Kheirallah, A. K.; Villarese, P.; Hypolite, G.; Garnache-Ottou, F.; Castaigne, S.; Boissel, N.; Asnafi, V.; Preudhomme, C.; Dombret, H.; Laurenti, E.; Macintyre, E.
10.1101/2019.12.10.870121 — cancer biology — Posted on 2020-03-13
2426 Super-resolved spatial transcriptomics by deep data fusion
Bergenstrahle, L.; He, B.; Bergenstrahle, J.; Andersson, A.; Lundeberg, J.; Zou, J.; Maaskola, J.
10.1101/2020.02.28.963413 — bioinformatics — Posted on 2020-03-13
2427 Inhibition of IL34 unveils tissue-selectivity and is sufficient to reduce microglial proliferation in chronic neurodegeneration
Obst, J.; Simon, E.; Martin-Estebane, M.; Pipi, E.; Barkwill, L.; Gonzalez-Rivera, I.; Buchanan, F.; Prescott, A. R.; Faust, D.; Fox, S.; Brownlees, J.; Taylor, D.; Perry, V. H.; Nuthall, H.; Atkinson, P. J.; Karran, E.; Routledge, C.; Gomez-Nicola, D.
10.1101/2020.03.09.976118 — neuroscience — Posted on 2020-03-13
2428 Evolution of genome structure in the Drosophila simulans species complex
Chakraborty, M.; Chang, C.-H.; Khost, D.; Vedanayagam, J.; Adrion, J. R.; Liao, Y.; Montooth, K. L.; Meiklejohn, C. D.; Larracuente, A. M.; Emerson, J. J.
10.1101/2020.02.27.968743 — genomics — Posted on 2020-03-13
2431 Pregnancy and obesity modify the epithelial composition and hormone signaling state of the human breast
Murrow, L. M.; Weber, R. J.; Caruso, J.; McGinnis, C. S.; Gascard, P.; Borowsky, A. D.; Desai, T. A.; Thomson, M.; Tlsty, T. D.; Gartner, Z. J.
10.1101/430611 — systems biology — Posted on 2020-03-13
2433 Cell wall remodeling and vesicle trafficking mediate the root clock in Arabidopsis
Wachsman, G.; Zhang, J.; Moreno-Risueno, M. A.; Anderson, C. T.; Benfey, P. N.
10.1101/2020.03.10.985747 — plant biology — Posted on 2020-03-13
2435 Input connectivity reveals additional heterogeneity of dopaminergic reinforcement in Drosophila
Otto, N.; Pleijzier, M. W.; Morgan, I. C.; Edmonson-Stait, A. J.; Heinz, K. J.; Stark, I.; Dempsey, G.; Ito, M.; Kapoor, I.; Hsu, J.; Schlegel, P. M.; Bates, A. S.; Feng, L.; Costa, M.; Ito, K.; Bock, D. D.; Rubin, G. M.; Jefferis, G. S. X. E.; Waddell, S.
10.1101/2020.02.19.952648 — neuroscience — Posted on 2020-03-13
2436 Individual differences in successful self-regulation of the dopaminergicmidbrain
Hellrung, L.; Kirschner, M.; Sulzer, J.; Sladky, R.; Scharnowski, F.; Herdener, M.; Tobler, P. N.
10.1101/863639 — neuroscience — Posted on 2020-03-13
2438 Lutein restores synaptic functionality in a C. elegans model for mitochondrial complex I deficiency
Maglioni, S.; Schiavi, A.; Melcher, M.; Brinkmann, V.; Luo, Z.; Raimundo, N.; Laromaine, A.; Meyer, J.; Distelmaier, F.; Ventura, N.
10.1101/2020.02.20.957225 — neuroscience — Posted on 2020-03-13
2440 An unusual MHC molecule generates protective CD8+ T cell responses to chronic infection
Tsitsiklis, A.; Bangs, D. J.; Lutes, L. L.; Chan, S.-W.; Geiger, K.; Modzelewski, A. J.; Labarta-Bajo, L.; Wang, Y.; Zuniga, E. I.; Dai, S.; Robey, E. A.
10.1101/2020.02.03.932848 — immunology — Posted on 2020-03-13
2443 Only 40% of the world's forests are in good health
Grantham, H. S.; Duncan, A.; Evans, T. D.; Jones, K. R.; Beyer, H.; Schuster, R.; Walston, J.; Ray, J.; Robinson, J.; Callow, M.; Clements, T.; Costa, H.; DeGemmis, A.; Elsen, P. R.; Ervin, J.; Franco, P.; Goldman, E.; Goetz, S.; Hansen, A.; Hofsvang, E.; Jantz, P.; Jupiter, S.; Kang, A.; Langhammer, P.; Laurance, W. F.; Liberman, S.; Linkie, M.; Malhi, Y.; Maxwell, S. L.; Mendez, M.; Mittermeier, R.; Murray, N.; Possingham, H.; Radachowsky, J.; Samper, C.; Silverman, J.; Shapiro, A.; Strassburg, B.; Stevens, T.; Stokes, E.; Taylor, R.; Tear, T.; Tizard, R.; Venter, O.; Visconti, P.; Wang, S.;
10.1101/2020.03.05.978858 — ecology — Posted on 2020-03-13
2445 The structures of natively assembled clathrin coated vesicles
Paraan, M.; Mendez, J. H.; Sharum, S.; Kurtin, D.; He, H.; Stagg, S. M.
10.1101/2020.01.28.923128 — biophysics — Posted on 2020-03-13
2449 Single-cell chromatin accessibility in glioblastoma delineates cancer stem cell heterogeneity predictive of survival
Guilhamon, P.; Kushida, M. M.; Nikolic, A.; Singhal, D.; MacLeod, G.; Tonekaboni, S. A. M.; Cavalli, F. M.; Arlidge, C.; Rajakulendran, N.; Rastegar, N.; Hao, X.; Hassam, R.; Smith, L. J.; Whetstone, H.; Coutinho, F. J.; Nadorp, B.; Ellestad, K. I.; Luchman, A. H.; Chan, J. A.; Shoichet, M. S.; Taylor, M. D.; Haibe-Kains, B.; Weiss, S.; Angers, S.; Gallo, M.; Dirks, P.; Lupien, M.
10.1101/370726 — cancer biology — Posted on 2020-03-13
2450 Lysine & Arginine Protein Post-translational Modifications by Enhanced DIA Libraries: Quantification in Murine Liver Disease
Robinson, A. E.; Binek, A.; Venkatraman, V.; Searle, B. C.; Holewinski, R.; Rosenberger, G.; Parker, S. J.; Basisty, N.; Xie, X.; Lund, P. J.; Saxena, G.; Mato, J. M.; Garcia, B. A.; Schilling, B.; Lu, S. C.; Van Eyk, J. E.
10.1101/2020.01.17.910943 — systems biology — Posted on 2020-03-13
2451 ProGen: Language Modeling for Protein Generation
Madani, A.; McCann, B.; Naik, N.; Keskar, N. S.; Anand, N.; Eguchi, R. R.; Huang, P.; Socher, R.
10.1101/2020.03.07.982272 — synthetic biology — Posted on 2020-03-13
2458 PhenomeXcan: Mapping the genome to the phenome through the transcriptome
Pividori, M.; Rajagopal, P. S.; Barbeira, A. N.; Liang, Y.; Melia, O.; Bastarache, L.; Park, Y.; The GTEx Consortium, ; Wen, X.; Im, H. K.
10.1101/833210 — genetics — Posted on 2020-03-13
2459 PhenomeXcan: Mapping the genome to the phenome through the transcriptome
Pividori, M.; Rajagopal, P. S.; Barbeira, A. N.; Liang, Y.; Melia, O.; Bastarache, L.; Park, Y.; The GTEx Consortium, ; Wen, X.; Im, H. K.
10.1101/833210 — genetics — Posted on 2020-03-13
2460 Disentangling Sources of Gene Tree Discordance in Phylogenomic Datasets: Testing Ancient Hybridizations in Amaranthaceae s.l.
Morales-Briones, D. F.; Kadereit, G.; Tefarikis, D. T.; Moore, M.; Smith, S. A.; Brockington, S. F.; Timoneda, A.; Yim, W. C.; Cushman, J. C.; Yang, Y.
10.1101/794370 — evolutionary biology — Posted on 2020-03-13
2462 An interaction between Gβγ and RNA polymerase II regulates transcription in cardiac fibroblasts
Khan, S. M.; Martin, R. D.; Gora, S.; Bouazza, C.; Jones-Tabah, J.; Zhang, A.; MacKinnon, S.; Trieu, P.; Clarke, P. B.; Tanny, J. C.; Hebert, T. E.
10.1101/415935 — biochemistry — Posted on 2020-03-13
2463 An interaction between Gβγ and RNA polymerase II regulates transcription in cardiac fibroblasts
Khan, S. M.; Martin, R. D.; Gora, S.; Bouazza, C.; Jones-Tabah, J.; Zhang, A.; MacKinnon, S.; Trieu, P.; Clarke, P. B.; Tanny, J. C.; Hebert, T. E.
10.1101/415935 — biochemistry — Posted on 2020-03-13
2466 Laocoön: a tool for high-throughput automated cell counting
Lim, K. Y.; Louie, M.; La Torre, A.; Fairchild, C.; Korf, I.
10.1101/751073 — bioinformatics — Posted on 2020-03-13
2467 Unravelling the effects of methylphenidate on the dopaminergic and noradrenergic functional circuits
Dipasquale, O.; Martins, D.; Sethi, A.; Veronese, M.; Hesse, S.; Rullmann, M.; Sabri, O.; Turkheimer, F.; Harrison, N. A.; Mehta, M. A.; Cercignani, M.
10.1101/2020.03.09.983528 — neuroscience — Posted on 2020-03-13
2470 O-GlcNAcylation of SAMHD1 Indicating a Link between Metabolic Reprogramming and Anti-HBV Immunity
Hu, J.; Gao, Q.; Yang, Y.; Xia, J.; Zhang, W.; Chen, Y.; Zhou, Z.; Chang, L.; Hu, Y.; Zhou, H.; Liang, L.; Li, X.; Long, Q.; Wang, K.; Huang, A.; Tang, N.
10.1101/2020.03.09.983338 — microbiology — Posted on 2020-03-13
2471 Efficient and Flexible Integration of Variant Characteristics in Rare Variant Association Studies Using Integrated Nested Laplace Approximation
Susak, H.; Serra-Saurina, L.; Rabionet Janssen, R.; Domenech, L.; Bosio, M.; Muyas, F.; Estivill, X.; Escaramis, G.; Ossowsky, S.
10.1101/2020.03.12.988584 — bioinformatics — Posted on 2020-03-12
2474 Uncovering new drug properties in target-based drug-drug similarity networks
Udrescu, L.; Bogdan, P.; Chis, A.; Sirbu, I. O.; Topirceanu, A.; Varut, R.-M.; Udrescu, M.
10.1101/2020.03.12.988600 — bioinformatics — Posted on 2020-03-12
2475 Varicella zoster virus encodes a viral decoy RHIM to inhibit cell death
Steain, M.; Baker, M. O. D. G.; Pham, C. L. L.; Gambin, Y.; Sierecki, E.; McSharry, B. P.; Avdic, S.; Slobedman, B.; Sunde, M.; Abendroth, A.
10.1101/2020.03.12.988659 — microbiology — Posted on 2020-03-12
2478 A Combined Evidence Approach to Prioritize Nipah Virus Inhibitors
Bhardwaj, A.; Sharma, N.; Upadhyay, A.; Kalia, K.; Kumar, R.; Tuteja, K.; Paul, P. R.; Covernton, E.; Sharma, T.; Scaria, V.
10.1101/2020.03.12.977918 — bioinformatics — Posted on 2020-03-12
2481 Discovery of a 382-nt deletion during the early evolution of SARS-CoV-2
Su, Y.; Anderson, D.; Young, B.; Zhu, F.; Linster, M.; Kalimuddin, S.; Low, J.; Yan, Z.; Jayakumar, J.; Sun, L.; Yan, G.; Mendenhall, I.; Leo, Y.-S.; Lye, D.; Wang, L.-F.; Smith, G.
10.1101/2020.03.11.987222 — microbiology — Posted on 2020-03-12
2485 Progressive changes in hippocampal stem cell properties ensure lifelong neurogenesis
Harris, L.; Rigo, P.; Stiehl, T.; Gaber, Z.; Austin, S. H. L.; Masdeu, M. d. M.; Edwards, A.; Urban, N.; Marciniak-Czochra, A.; Guillemot, F.
10.1101/2020.03.12.987107 — developmental biology — Posted on 2020-03-12
2487 A regulatory interface on RIPK2 is required for XIAP binding and NOD signaling activity
Heim, V. J.; Dagley, L. F.; Stafford, C.; Hansen, F. M.; Clayer, E.; Bankovacki, A.; Webb, A. I.; Lucet, I. S.; Silke, J.; Nachbur, U.
10.1101/2020.03.12.988725 — cell biology — Posted on 2020-03-12
2488 Filtering Variables for Supervised Sparse Network Analysis
Towle-Miller, L. M.; Miecznikowski, J. C.; Zhang, F.; Tritchler, D. L.
10.1101/2020.03.12.985077 — bioinformatics — Posted on 2020-03-12
2489 A bottom-up approach for the de novo design of functional proteins
Yang, C.; Sesterhenn, F.; Bonet, J.; Aalen, E. v.; Scheller, L.; Abriata, L.; Cramer, J.; Wen, X.; Rosset, S.; Georgeon, S.; Jardetzky, T. S.; Krey, T.; Fussenegger, M.; Merkx, M.; Correia, B.
10.1101/2020.03.11.988071 — bioengineering — Posted on 2020-03-12
2490 Replacing the Calvin cycle with the reductive glycine pathway in Cupriavidus necator
Claassens, N. J.; Bordanaba-Florit, G.; Cotton, C. A. R.; de Maria, A.; Finger-Bou, M.; Friedeheim, L.; Giner-Laguarda, N.; Munar-Palmer, M.; Newell, W.; Scarinci, G.; Verbunt, J.; de Vries, S. T.; Yilmaz, S.; Bar-Even, A.
10.1101/2020.03.11.987487 — synthetic biology — Posted on 2020-03-12
2496 TrkB agonist antibody delivery to the brain using a TfR1 specific BBB shuttle provides neuroprotection in a mouse model of Parkinson's Disease
Clarke, E.; Sinclair, L.; Fletcher, E. J. R.; Krawczun-Rygmaczewska, A.; Duty, S.; Stocki, P.; Rutowski, J. L.; Doherty, P.; Walsh, F. S.
10.1101/2020.03.12.987313 — neuroscience — Posted on 2020-03-12
2502 Testing the two-step model of plant root microbiome acquisition under multiple plant species and soil sources
Barajas, H. R.; Martinez-Sanchez, S.; Romero, M. F.; Hernandez-Alvarez, C.; Servin-Gonzalez, L.; Peimbert, M.; Cruz-Ortega, R.; Garcia-Oliva, F.; Alcaraz, L. D.
10.1101/2020.03.11.988014 — microbiology — Posted on 2020-03-12
2506 Cell-based analysis of CAD variants identifies individuals likely to benefit from uridine therapy
Del Cano-Ochoa, F.; Ng, B. G.; Abedalthagafi, M.; Almannai, M.; Cohn, R. D.; Costain, G.; Elpeleg, O.; Houlden, H.; Ghayoor Karimiani, E.; Liu, P.; Manzini, M. C.; Maroofian, R.; Muriello, M.; Al-Otaibi, A.; Patel, H.; edvardson, S.; Sutton, V. R.; Toosi, M. B.; Wolfe, L. A.; Rosenfeld, J. A.; Freeze, H. H.; Ramon-Maiques, S.
10.1101/2020.03.11.987651 — genetics — Posted on 2020-03-12
2514 A Piezo1 open state reveals a multi-fenestrated ion permeation pathway
Jiang, W.; Del Rosario, J. S.; Botello-Smith, W. M.; Zhao, S.; Lin, Y.-C.; Zhang, H.; Lacroix, J. J.; Rohacs, T.; Luo, Y. L.
10.1101/2020.03.12.988378 — biophysics — Posted on 2020-03-12
2515 The role of the C2A domain of synaptotagmin 1 in asynchronous neurotransmitter release
Shields, M. C.; Bowers, M. R.; Kramer, H. L.; Fulcer, M. M.; Perinet, L. C.; Metz, M. J.; Reist, N. E.
10.1101/2020.03.11.973461 — neuroscience — Posted on 2020-03-12
2516 Standardization and Harmonization of Distributed Multi-National Proteotype Analysis supporting Precision Medicine Studies
Xuan, Y.; Bateman, N. W.; Gallien, S.; Goetze, S.; Zhou, Y.; Navarro, P.; Hu, M.; Parikh, N.; Hood, B. L.; Conrads, K. A.; Loosse, C.; Kitata, R. B.; Piersma, S. R.; Chiasserini, D.; Zhu, H.; Hou, G.; Tahir, M.; Macklin, A.; Khoo, A.; Sun, X.; Crossett, B.; Sickmann, A.; Chen, Y.-J.; Jimenez, C. R.; Zhou, H.; Liu, S.; Larsen, M. R.; Kislinger, T.; Chen, Z.; Parker, B. L.; Cordwell, S. J.; Wollscheid, B.; Conrads, T. P.
10.1101/2020.03.12.988089 — molecular biology — Posted on 2020-03-12
2518 Genomic signals of admixture and reinforcement between two closely related species of European sepsid flies
Giesen, A.; Blanckenhorn, W. U.; Schaefer, M. A.; Shimizu, K. K.; Shimizu-Inatsugi, R.; Misof, B.; Niehuis, O.; Wilbrandt, J.; Petersen, M.; Podsiadlowski, L.; Lischer, H. E. L.; Aeschbacher, S.; Kapun, M.
10.1101/2020.03.11.985903 — evolutionary biology — Posted on 2020-03-12
2520 Disruption of oncogenic targeting by ISWI via phosphorylation of a prion-like domain
Chen, M.; Foster, J. P.; Lock, I. C.; Leisenring, N. H.; Daniel, A. R.; Floyd, W.; Xu, E. S.; Davis, I. J.; Kirsch, D. G.
10.1101/2020.03.11.987750 — cancer biology — Posted on 2020-03-12
2527 Altered kinetics of circulating progenitor cells in cardiopulmonary bypass (CPB) associated vasoplegic patients: An observational study
Nandi, S.; Kumari, C.; Potunuru, U. R.; Nathan, A. A.; Gopal, J.; Menon, G. I.; Siddharthan, R.; Dixit, M.; Thangaraj, P. R.
10.1101/2020.03.11.987099 — physiology — Posted on 2020-03-12
2529 Confound modelling in UK Biobank brain imaging
Alfaro-Almagro, F.; McCarthy, P.; Afyouni, S.; Andersson, J. L. R.; Bastiani, M.; Miller, K. L.; Nichols, T.; Smith, S. M.
10.1101/2020.03.11.987693 — neuroscience — Posted on 2020-03-12
2532 Antibiotic hypersensitivity signatures identify targets for attack in the Acinetobacter baumannii cell envelope
Geisinger, E.; Mortman, N. J.; Dai, Y.; Cokol, M.; Syal, S.; Farinha, A.; Fisher, D.; Tang, A.; Lazinski, D. W.; Wood, S.; Anthony, J.; Opijnen, T.; Isberg, R. R.
10.1101/2020.03.11.987479 — microbiology — Posted on 2020-03-12
2533 Mitochondrial Complex II In Intestinal Epithelial Cells Regulates T-cell Mediated Immunopathology
Fujiwara, H.; Mathew, A. V.; Kovalneko, I.; Pal, A.; Lee, H.-J.; Peltier, D.; Kim, S.; Liu, C.; Oravecz-Wilson, K.; Li, L.; Sun, Y.; Byun, J.; Saunders, T.; Rehemtulla, A.; Lyssiotis, C. A.; Pennathur, S.; Reddy, P.
10.1101/2020.03.12.978692 — immunology — Posted on 2020-03-12
2535 Year-to-year crop shifts promote weed diversity in tropical permanent rainfed cultivation
Neyret, M.; de Rouw, A.; Colbach, N.; Robain, H.; Soulileuth, B.; Valentin, C.
10.1101/2020.03.12.988469 — ecology — Posted on 2020-03-12
2537 Feeding-dependent tentacle development in the sea anemone Nematostella vectensis
Ikmi, A.; Steenbergen, P. J.; Anzo, M.; McMullen, M. R.; Stokkermans, A.; Ellington, L. R.; Gibson, M. C.
10.1101/2020.03.12.985168 — developmental biology — Posted on 2020-03-12
2539 Split-TurboID enables contact-dependent proximity labeling in cells
Cho, K. F.; Branon, T. C.; Rajeev, S.; Svinkina, T.; Udeshi, N. D.; Thoudam, T.; Kwak, C.; Rhee, H.-W.; Lee, I.-K.; Carr, S. A.; Ting, A. Y.
10.1101/2020.03.11.988022 — cell biology — Posted on 2020-03-12
2540 Ursolic acid inhibits cell migration and promotes JNK-dependent lysosomal associated cell death in Glioblastoma multiforme cells
Conway, G. E.; Zizyte, D.; Mondala, J. R. M.; He, Z.; Lynam, L.; Lecourt, M.; Barcia, C.; Howe, O.; Curtin, J.
10.1101/2020.03.11.987578 — cancer biology — Posted on 2020-03-12
2543 Three-dimensional genome structure and chromatin accessibility reorganization during in vivo induction of human T cell tolerance
Li, R.; Guo, H.; Hou, Y.; Liu, S.; Wang, M.; Peng, T.; Zhao, X.; Lu, L.; Han, Y.; Shao, Y.; Chang, Y.-J.; Li, C.; Huang, X.
10.1101/2020.03.11.988253 — bioinformatics — Posted on 2020-03-12
2544 Long-read transcriptome data of bee fungal parasite, Nosema ceranae
Guo, R.; Chen, H.; Du, Y.; Fan, Y.; Jiang, H.; Zheng, Y.; Chen, D.
10.1101/2020.03.11.987271 — bioinformatics — Posted on 2020-03-12
2546 Development of a clostridia-based cell-free system for prototyping genetic parts and metabolic pathways
Kruger, A.; Mueller, A. P.; Rybnicky, G. A.; Engle, N. L.; Yang, Z. K.; Tschaplinski, T. J.; Simpson, S. D.; Koepke, M.; Jewett, M. C.
10.1101/2020.03.11.987826 — synthetic biology — Posted on 2020-03-12
2548 Innate sensitivity and plastic mechanisms in auditory cortex for reliable maternal behavior
Schiavo, J. K.; Valtcheva, S.; Bair-Marshall, C.; Song, S. C.; Martin, K. A.; Froemke, R.
10.1101/2020.03.11.987941 — neuroscience — Posted on 2020-03-12
2550 Ketamine restores escape behavior by re-engaging dopamine systems to drive cortical spinogenesis
Wu, M.; Minkowicz, S.; Dumrongprechachan, V.; Hamilton, P.; Xiao, L.; Kozorovitskiy, Y.
10.1101/2020.03.11.987818 — neuroscience — Posted on 2020-03-12
2552 Novel and potent inhibitors targeting DHODH, a rate-limiting enzyme in de novo pyrimidine biosynthesis, are broad-spectrum antiviral against RNA viruses including newly emerged coronavirus SARS-CoV-2
Xiong, R.; Zhang, L.; Li, S.; Sun, Y.; Ding, M.; Wang, Y.; Zhao, Y.; Wu, Y.; Shang, W.; Jiang, X.; Shan, J.; Shen, Z.; Tong, Y.; Xu, L.; Chen, Y.; Liu, Y.; Zou, G.; Lavillete, D.; Zhao, Z.; Wang, R.; Zhu, L.; Xiao, G.; Lan, K.; Li, H.; Xu, K.
10.1101/2020.03.11.983056 — microbiology — Posted on 2020-03-12
2554 Morphological profiling of tubercule bacilli identifies drug pathways of action
Smith, T. C.; Pullen, K. M.; Olson, M. C.; McNellis, M. E.; Richardson, I.; Hu, S.; Larkins-Ford, J.; Wang, X.; Freundlich, J. S.; Ando, D. M.; Aldridge, B.
10.1101/2020.03.11.987545 — microbiology — Posted on 2020-03-12
2556 3D Genome Analysis Identifies Enhancer Hijacking Mechanism for High-Risk Factors in Human T-Lineage Acute Lymphoblastic Leukemia
Yang, L.; Chen, F.; Zhu, H.; Chen, Y.; Dong, B.; Shi, M.; Wang, W.; Jiang, Q.; Zhang, L.; Huang, X.; Zhang, M. Q.; Wu, H.
10.1101/2020.03.11.988279 — genomics — Posted on 2020-03-12
2558 No one-size-fits-all solution to clean GBIF
Zizka, A.; Antunes Carvalho, F.; Calvente, A.; Rocio Baez-Lizarazo, M.; Cabral, A.; Ramos Coelho, J. F.; Colli-Silva, M.; Ramos Fantinati, M.; Ferreira Fernandes, M.; Ferreira-Araujo, T.; Gondim Lambert Moreira, F.; da Cunha Santos, N. M.; Borges Santos, T. A.; Clicia dos Santos-Costa, R.; Cabreirinha Serrano, F.; Alves da Silva, A. P.; Cavalcante de Souza, P. G.; Calisto Tomaz, E.; de Souza Soares, A.; Fonseca Vale, V.; Vieira, T. L.; Antonelli, A.
10.1101/2020.03.12.974543 — ecology — Posted on 2020-03-12
2563 From Farm to Pharmacy: Strawberry-Enabled Oral Delivery of Protein Drugs
Lamson, N. G.; Fein, K. C.; Gleeson, J. P.; Xian, S.; Newby, A.; Chaudhary, N.; Melamed, J. R.; Cochran, K.; Ball, R. L.; Suri, K.; Ahuja, V.; Zhang, A.; Berger, A.; Kolodieznyi, D.; Schmidt, B. F.; Silva, G. L.; Whitehead, K. A.
10.1101/2020.03.11.987461 — bioengineering — Posted on 2020-03-12
2564 How to navigate the myosin-V motor through the actin network
Spieler, P.; Oberhofer, A.; Zimmermann, D.; Brames, E.; Hume, A. N.; Oekten, Z.
10.1101/2020.03.11.987495 — biochemistry — Posted on 2020-03-12
2569 Early-life microbial intervention reduces colitis risk promoted by antibiotic-induced gut dysbiosis
Miyoshi, J.; Miyoshi, S.; Delmont, T. O.; Cham, C.; Lee, S. T. M.; Sakatani, A.; Yang, K.; Shan, Y.; Kiefl, E.; Yousef, M.; Crosson, S.; Sogin, M.; Antonopoulos, D. A.; Eren, A. M.; Leone, V.; Chang, E. B.
10.1101/2020.03.11.987412 — microbiology — Posted on 2020-03-12
2571 Extracellular Ca2+-sensitive fluorescent protein biosensor based on a collagen-binding domain
Okkelman, I. A.; McGarrigle, R.; O' Carroll, S.; Carvajal Berrio, D.; Schenke-Layland, K.; Hynes, J.; Dmitriev, R. I.
10.1101/2020.03.11.987446 — bioengineering — Posted on 2020-03-12
2573 Revealing the polarity of actin filaments in intact cells
Martins, B.; Sorrentino, S.; Chung, W.-L.; Tatli, M.; Medalia, O.; Eibauer, M.
10.1101/2020.03.11.987263 — cell biology — Posted on 2020-03-12
2575 Kernel integration by Graphical LASSO
Noergaard, S. K.; Linder-Steinlein, K.; Eliasen, A.; Stokholm, J.; Chawes, B. L.; Bonnelykke, K.; Bisgaard, H.; Smilde, A. K.; Rasmussen, M. A.
10.1101/2020.03.11.986968 — bioinformatics — Posted on 2020-03-12
2576 Autocrine IL11 cis-signaling in hepatocytes is an initiating nexus between lipotoxicity and non-alcoholic steatohepatitis
Dong, J.; Adami, E.; Chothani, S.; Viswanathan, S.; NG, B.; Lim, W.-W.; Singh, B. K.; Zhou, J.; Ko, N.; Shekeran, S. G.; Tan, J.; Lim, S. Y.; Wang, M.; Lio, P. M.; Yen, P. M.; Schafer, S.; Cook, S. A.; Widjaja, A. A.
10.1101/2020.03.11.986802 — molecular biology — Posted on 2020-03-12
2586 Identification of Candida glabrata Transcriptional Regulators that Govern Stress Resistance and Virulence
Filler, E. E.; Liu, Y.; Solis, N. V.; Diaz, L. F.; Edwards, J. E.; Filler, S. G.; Yeaman, M. R.
10.1101/2020.03.10.986703 — microbiology — Posted on 2020-03-12
2588 Optimization of an Experimental Vaccine to Prevent Escherichia coli Urinary Tract Infection
Forsyth, V. S.; Himpsl, S. D.; Smith, S. N.; Sarkissan, C. A.; Mike, L. A.; Stocki, J. A.; Sintsova, A.; Alteri, C.; Mobley, H. L. T.
10.1101/2020.03.10.986729 — microbiology — Posted on 2020-03-12
2589 Plasticity as an Underlying Mechanism of Tumor Heterogeneity in Breast Cancer
Akbar, M. W.; Isbilen, M.; Kuckkaraduman, B.; Demirkol Canli, S.; Dedeoglu, E.; Azizolli, S.; Cela, I.; Akcay, A. G.; Hakanoglu, H.; Gure, A. O.
10.1101/2020.03.11.987511 — cancer biology — Posted on 2020-03-12
2590 A single cell atlas reveals distinct immune landscapes in transplant and primary tumors that determine response or resistance to immunotherapy
Wisdom, A. J.; Mowery, Y. M.; Hong, C. S.; Qin, X.; Zhang, D.; Himes, J. E.; Chen, L.; Fradin, H.; Muise, E. S.; Xu, E. S.; Carpenter, D. J.; Kent, C. L.; Smythe, K. S.; Williams, N.; Luo, L.; Ma, Y.; Owzar, K.; Bradley, T.; Kirsch, D. G.
10.1101/2020.03.11.978387 — cancer biology — Posted on 2020-03-12
2592 A data-driven drug repositioning framework discovered a potential therapeutic agent targeting COVID-19
Ge, Y.; Tian, T.; Huang, S.; Wan, F.; Li, J.; Li, S.; Yang, H.; Hong, L.; Wu, N.; Yuan, E.; Cheng, L.; Lei, Y.; Shu, H.; Feng, X.; Jiang, Z.; Chi, Y.; Guo, X.; Cui, L.; Xiao, L.; Li, Z.; Yang, C.; Miao, Z.; Tang, H.; Chen, L.; Zeng, H.; Zhao, D.; Zhu, F.; Shen, X.; Zeng, J.
10.1101/2020.03.11.986836 — systems biology — Posted on 2020-03-12
2593 The inhaled corticosteroid ciclesonide blocks coronavirus RNA replication by targeting viral NSP15
Matsuyama, S.; Kawase, M.; Nao, N.; Shirato, K.; Ujike, M.; Kamitani, W.; Shimojima, M.; Fukushi, S.
10.1101/2020.03.11.987016 — microbiology — Posted on 2020-03-12
2594 Pathogenic LRRK2 R1441C mutation is associated with striatal alterations
Xenias, H.; Chen, C.; Kang, S.; Shanmugasundaram, B.; Cherian, S.; Situ, X.; Scesa, G.; Chan, C. S.; Parisiadou, L.
10.1101/2020.03.11.986455 — neuroscience — Posted on 2020-03-12
2595 A human monoclonal 1 antibody blocking SARS-CoV-2 infection
Wang, C.; Li, W.; Drabek, D.; Okba, N. M. A.; van Haperen, R.; Osterhaus, A. D. M. E.; van Kuppeveld, F. J. M.; Haagmans, B. L.; Grosveld, F.; Bosch, B.-J.
10.1101/2020.03.11.987958 — microbiology — Posted on 2020-03-12
2596 Age-dependent DNA methylation Parenclitic Networks in family-based cohort patients with Down Syndrome
Krivonosov, M.; Nazarenko, T.; Bacalini, M. G.; Franceschi, C.; Zaikin, A.; Ivanchenko, M.
10.1101/2020.03.10.986505 — bioinformatics — Posted on 2020-03-12
2597 SUMOylation of rice DELLA SLR1 modulates transcriptional responses and improves yield under salt stress
Goncalves, N. M.; Fernandes, T.; Nunes, C.; Rosa, M. T. G.; Matiolli, C. C.; Rodrigues, M. A. A.; Barros, P. M.; Oliveira, M. M.; Abreu, I. A.
10.1101/2020.03.10.986224 — plant biology — Posted on 2020-03-12
2601 Microbial function and genital inflammation in young South African women at high risk of HIV infection
Alisoltani, A.; Manhanzva, M. T.; Potgieter, M. G.; Balle, C.; Bell, L.; Ross, E.; Iranzadeh, A.; du Plessis, M.; Radzey, N.; McDonald, Z.; Calder, B.; Allali, I.; Mulder, N.; Dabee, S.; Barnabas, S.; Gamieldien, H.; Godzik, A.; Blackburn, J. M.; Tabb, D. L.; Bekker, L.-G.; Jaspan, H. B.; Passmore, J.-A. S.; Masson, L.
10.1101/2020.03.10.986646 — microbiology — Posted on 2020-03-12
2605 Methods for Extraction and Detection of Bacteriophage DNA from the Sputum of Patients with Cystic Fibrosis
Burgener, E. B.; Secor, P. R.; Tracy, M. C.; Sweere, J. M.; Bik, E. M.; Milla, C. E.; Bollyky, P.
10.1101/2020.03.10.986638 — microbiology — Posted on 2020-03-12
2609 APEX2 proximity proteomics resolves flagellum subdomains and identifies flagellum tip-specific proteins in Trypanosoma brucei
Velez-Ramirez, D. E.; Shimogawa, M. M.; Ray, S.; Lopez, A.; Rayatpisheh, S.; Langousis, G.; Gallagher-Jones, M.; Dean, S.; Wohlschlegel, J. A.; Hill, K. L.
10.1101/2020.03.09.984815 — microbiology — Posted on 2020-03-12
2610 Plastidic Δ6 Fatty-Acid Desaturases With Distinctive Substrate Specificity Regulate The Pool Of C18-PUFAs In The Ancestral Picoalga Ostreococcus tauri
Degraeve-Guilbault, C.; Gomez, R. E.; Lemoigne, C.; Pankasem, N.; Morin, S.; Tuphile, K.; Joubes, J.; Jouhet, J.; Gronnier, J.; Suzuki, I.; Domergue, F.; Corellou, F.
10.1101/2020.03.10.986216 — biochemistry — Posted on 2020-03-12
2613 Periodic propagating activation waves coordinate Rho GTPase network dynamics at the leading and trailing edges during cell migration
Bolado-Carrancio, A.; Rukhlenko, O. S.; Nikonova, E.; Tsyganov, M. A.; Wheeler, A.; Munoz, A. G.; Kolch, W.; von Kriegsheim, A.; Kholodenko, B. N.
10.1101/2020.03.09.984054 — systems biology — Posted on 2020-03-12
2616 Unravelling the phylogenomic relationships of the most diverse African palm genus Raphia (Calamoideae, Arecaceae)
Helmstetter, A. J.; Mogue Kamga, S.; Bethune, K.; Lautenschläeger, T.; Zizka, A.; Bacon, C. D.; Wieringa, J. J.; Stauffer, F.; Antonelli, A.; Sonke, B.; Couvreur, T. L. P.
10.1101/2020.03.09.984351 — plant biology — Posted on 2020-03-12
2618 Cognitive and brain development is independently influenced by socioeconomic status and polygenic scores for educational attainment.
Judd, N.; Sauce, B.; Wiedenhoeft, J.; Tromp, J.; Chaarani, B.; Schliep, A.; van Noort, B.; Penttila, J.; Grimmer, Y.; Insensee, C.; Becker, A.; Banaschewski, T.; Bokde, A.; Quinlan, E. B.; Desrivieres, S.; Flor, H.; Grigis, A.; Gowland, P.; Heinz, A.; Ittermann, B.; Martinot, J.-L.; Martinot, M.-L.; Artiges, E.; Nees, F.; Orfanos, D.; Paus, T.; Poustka, L.; Hohmann, S.; Millenet, S.; Frohner, J.; Smolka, M.; Walter, H.; Whelan, R.; Schumann, G.; Garavan, H.; Klingberg, T.
10.1101/866624 — neuroscience — Posted on 2020-03-12
2619 Distinct Neuronal Populations Contribute to Trace Conditioning and Extinction Learning in the Hippocampal CA1
Hansen, K. R.; Mount, R.; Sridhar, S.; Mohammed, A. I.; Abdulkerim, M. E.; Kessel, R.; Nazer, B.; Gritton, H. J.; Han, X.
10.1101/2020.03.06.980854 — neuroscience — Posted on 2020-03-12
2621 Calcium-independent astrocytic lipid release modulates neuronal activity through Kv channels
Wang, F.; Bradshaw, H. B.; Jablonska, B.; Pena, S. E.; Xavier, J.; Gong, S.; Li, B.; Chandler-Militello, D.; Bekar, L. K.; Smith, N. A.
10.1101/2020.01.12.903393 — neuroscience — Posted on 2020-03-12
2622 An Xist-dependent protein assembly mediates Xist localization and gene silencing
Pandya-Jones, A.; Markaki, Y.; Serizay, J.; Chitiashvili, T.; Mancia, W.; Damianov, A.; Chronis, K.; Papp, B.; Chen, C.-K.; McKee, R.; Wang, X.-J.; Chau, A.; Leonhardt, H.; Zheng, S.; Guttman, M.; Black, D. L.; Plath, K.
10.1101/2020.03.09.979369 — molecular biology — Posted on 2020-03-12
2624 Unlocking the genomic taxonomy of the Prochlorococcus collective
Tschoeke, D. A.; Vidal, L. M.; Campeao, M.; Salazar, V. W.; Swings, J.; Thompson, F. L.; Thompson, C. C.
10.1101/2020.03.09.980698 — microbiology — Posted on 2020-03-12
2625 Rapamycin-dependent delocalization as a novel tool to reveal protein-protein interactions in plants
Winkler, J.; Mylle, E.; De Meyer, A.; Pavie, B.; Merchie, J.; Grones, P.; Van Damme, D.
10.1101/2020.03.09.983270 — cell biology — Posted on 2020-03-12
2627 Nonalcoholic fatty liver disease is associated with decreased hepatocyte mitochondrial respiration but not mitochondrial number
Sinton, M. C.; Meseguer-Ripolles, J.; Lucendo-Villarin, B.; Lyall, M. J.; Carter, R. N.; Morton, N. M.; Hay, D. C.; Drake, A. J.
10.1101/2020.03.10.985200 — biochemistry — Posted on 2020-03-12
2628 Genome wide-association study identifies novel loci in the Primary Open-Angle African American Glaucoma Genetics (POAAGG) study
Gudiseva, H. V.; Verma, S. S.; Chavali, V. R. M.; Salowe, R.; Lucas, A.; Collins, D. W.; Rathi, S.; He, J.; Lee, R.; Merriam, S.; Bowman, A. S.; mchugh, c. p.; Zody, M. C.; Pistilli, M.; Khachatryan, N.; Ebenezer, D.; Windell, M.; Weiner, M.; Henderer, J.; Ross, A.; Cui, Q. N.; Addis, V.; Lehman, A.; Miller-Ellis, E.; Sankar, P.; Varma, R.; Williams, S. M.; Ying, G.-S.; Moore, J. H.; Ritchie, M. D.; O'Brien, J. M.
10.1101/2020.02.27.968156 — genetics — Posted on 2020-03-12
2629 An antimicrobial origin of targeting peptides to endosymbiotic organelles
Garrido, C. O.; Caspari, O. D.; Choquet, Y.; Wollman, F.-A.; Lafontaine, I.
10.1101/2020.03.04.974964 — evolutionary biology — Posted on 2020-03-12
2630 Heme A-containing oxidases evolved in the ancestors of iron oxidizing bacteria
Degli Esposti, M.; Garcia-Meza, V.; Ceniceros Gomez, A.; Moya-Beltran, A.; Quatrini, R.; Hederstedt, L.
10.1101/2020.03.01.968255 — evolutionary biology — Posted on 2020-03-12
2632 Population Structure in a Direct-Developing Marine Isopod
Pearman, W. S.; Wells, S. J.; Silander, O. K.; Freed, N. E.; Dale, J.
10.1101/2020.03.01.971333 — ecology — Posted on 2020-03-12
2635 Loss of Corneal Raver2 Expression in Aniridia Associated Keratopathy
Das, S. K.; Carroll, L.; Holt, D.; zhang, X.; Uehara, H.; Archer, B.; Ambati, J.; Ambati, B. K.
10.1101/2020.02.21.959585 — developmental biology — Posted on 2020-03-12
2639 Neural activity during a simple reaching task in macaques is counter to theories of basal ganglia-thalamic communication
Schwab, B. C.; Kase, D.; Zimnik, A.; Rosenbaum, R.; Codianni, M. G.; Rubin, J. E.; Turner, R. S.
10.1101/546598 — neuroscience — Posted on 2020-03-12
2641 Thresholds for post-rebound SHIV control after CCR5 gene-edited autologous hematopoietic cell transplantation
Cardozo-Ojeda, E. F.; Duke, E. R.; Peterson, C. W.; Reeves, D. B.; Mayer, B. T.; Kiem, H.-P.; Schiffer, J. T.
10.1101/629717 — microbiology — Posted on 2020-03-12
2643 A minimum reporting standard for multiple sequence alignments
Wong, T. K.; Kalyaanamoorthy, S.; Meusemann, K.; Yeates, D. K.; Misof, B.; Jermiin, L. S.
10.1101/2020.01.15.907733 — bioinformatics — Posted on 2020-03-12
2648 Machine learning guided association of adverse drug reactions with in vitro target-based pharmacology
Ietswaart, R.; Arat, S.; Chen, A. X.; Farahmand, S.; Kim, B.; DuMouchel, W.; Armstrong, D.; Fekete, A.; Sutherland, J. J.; Urban, L.
10.1101/750950 — pharmacology and toxicology — Posted on 2020-03-12
2649 A thalamic reticular circuit for head direction cell tuning and spatial navigation
Vantomme, G.; Rovo, Z.; Cardis, R.; Beard, E.; Katsioudi, G.; Guadagno, A.; Perrenoud, V.; Fernandez, L. M. J.; Luthi, A.
10.1101/804575 — neuroscience — Posted on 2020-03-12
2650 Sensitization of knee-innervating sensory neurons by tumor necrosis factor-α activated fibroblast-like synoviocytes: an in vitro, co-culture model of inflammatory pain
Chakrabarti, S.; Hore, Z.; Pattison, L. A.; Lalnunhlimi, S.; Bhebhe, C. N.; Callejo, G.; Bulmer, D. C.; Taams, L. S.; Denk, F.; Smith, E. S. J.
10.1101/791251 — neuroscience — Posted on 2020-03-12
2651 The psychological correlates of distinct neural states occurring during wakeful rest
Karapanagiotidis, T.; Vidaurre, D.; Quinn, A. J.; Vatansever, D.; Poerio, G. L.; Turnbull, A.; Ho, N.; Leech, R.; Bernhardt, B.; Jefferies, E.; Margulies, D. S.; Nichols, T.; Woolrich, M. W.; Smallwood, J.
10.1101/2019.12.21.885772 — neuroscience — Posted on 2020-03-12
2653 Somatic evolution in non-neoplastic IBD-affected colon
Olafsson, S.; McIntyre, R.; Coorens, T.; Butler, T. M.; Jung, H.; Robinson, P.; Lee-Six, H.; Sanders, M.; Arestang, K.; Dawson, C.; Tripathi, M.; Strongili, K.; Hooks, Y.; Stratton, M. R.; Parkes, M.; Martincorena, I.; Raine, T.; Campbell, P.; Anderson, C.
10.1101/832014 — genetics — Posted on 2020-03-12
2656 Transit-amplifying cells coordinate changes in intestinal epithelial cell-type composition
Sanman, L. E.; Chen, I. W.; Bieber, J. M.; Steri, V.; Hann, B.; Wu, L. F.; Altschuler, S. J.
10.1101/840371 — cell biology — Posted on 2020-03-12
2657 A clinically and genomically annotated nerve sheath tumor biospecimen repository.
Pollard, K.; Banerjee, J.; Doan, X.; Wang, J.; Guo, X.; Allaway, R. J.; Langmead, S.; Slobogean, B.; Meyer, C.; Loeb, D.; Morris, C.; Belzberg, A.; Blakeley, J. O.; Rodriguez, F.; Guinney, J.; Gosline, S. J.; Pratilas, C. A.
10.1101/2019.12.19.871897 — cancer biology — Posted on 2020-03-12
2661 RUNX1 mitotically bookmarks target genes that are important for the mammary epithelial-to-mesenchymal transition
Rose, J. T.; Moskovitz, E.; Boyd, J. R.; Gordon, J. A.; Bouffard, N. A.; Fritz, A. J.; Illendula, A.; Bushweller, J. H.; Lian, J. B.; Stein, J. L.; Stein, G. S.; Zaidi, S.
10.1101/511410 — cancer biology — Posted on 2020-03-12
2666 Rational design of novel fluorescent enzyme biosensors for direct detection of strigolactones
Chesterfield, R. J.; Whitfield, J. H.; Pouvreau, B.; Cao, D.; Beveridge, C. A.; Vickers, C. E.
10.1101/2020.03.10.986562 — synthetic biology — Posted on 2020-03-12
2669 Genomic and dietary transitions during the Mesolithic and Early Neolithic in Sicily
van de Loosdrecht, M. S.; Mannino, M. A.; Talamo, S.; Villalba-Mouco, V.; Posth, C.; Aron, F.; Brandt, G.; Burri, M.; Freund, C.; Radzeviciute, R.; Stahl, R.; Wissgott, A.; Klausnitzer, L.; Nagel, S.; Meyer, M.; Tagliacozzo, A.; Piperno, M.; Tusa, S.; Collina, C.; Schimmenti, V.; Di Salvo, R.; Prüfer, K.; Hublin, J.-J.; Schiffels, S.; Jeong, C.; Haak, W.; Krause, J.
10.1101/2020.03.11.986158 — genetics — Posted on 2020-03-12
2674 Striatin is required for hearing and affects inner hair cells and ribbon synapses
Nadar Ponniah, P.; Taiber, S.; Caspi, M.; Koffler-Brill, T.; Dror, A. A.; Rubinstein, M.; Lang, R. W.; Avraham, K. B.; Rosin-Arbesfeld, R.
10.1101/2020.03.11.987396 — cell biology — Posted on 2020-03-11
2675 Role of syndecan-1 in the interaction between dendritic cells and T cells
Kouwenberg, M.; Rops, A. L.; Bakker-van Bebber, M.; Diepeveen, L.; Götte, M.; Hilbrands, L.; van der Vlag, J.
10.1101/2020.03.11.987602 — immunology — Posted on 2020-03-11
2676 Erythropoietin production?by the kidney and the liver in response to severe hypoxia evaluated by Western blotting with deglycosylation
Yasuoka, Y.; Fukuyama, T.; Izumi, Y.; Nakayama, Y.; Inoue, H.; Yanagita, K.; Oshima, T.; Yamazaki, T.; Uematsu, T.; Kobayashi, N.; Shimada, Y.; Nagaba, Y.; Mukoyama, M.; Yamashita, T.; Sato, Y.; Kawahara, K.; Nonoguchi, H.
10.1101/2020.03.11.987586 — physiology — Posted on 2020-03-11
2680 Network Organisation and the Dynamics of Tubules in the Endoplasmic Reticulum
Perkins, H.; Ducluzaux, P.; Woodman, P. G.; Allan, V. J.; Waigh, T. A.
10.1101/2020.03.11.987891 — biophysics — Posted on 2020-03-11
2683 Glucose-dependent activation, activity, and deactivation of beta cell networks in acute mouse pancreas tissue slices
Dolensek, J.; Skelin Klemen, M.; Gosak, M.; Krizancic-Bombek, L.; Pohorec, V.; Slak Rupnik, M.; Stozer, A.
10.1101/2020.03.11.986893 — physiology — Posted on 2020-03-11
2688 Astrocyte to microglia cross-talk in acute and chronic neuroinflammation is shaped by SFRP1
Rueda-Carrasco, J.; Mateo, M. I.; Borroto, A.; Martin-Bermejo, M. J.; Kummer, M. P.; Schwartz, S.; Lopez-Atalaya, J. P.; Alarcon, B.; Heneka, M. T.; Esteve, P.; Bovolenta, P.
10.1101/2020.03.10.982579 — neuroscience — Posted on 2020-03-11
2689 Small Molecule Targeting IRES Domain Inhibits Enterovirus 71 Replication via an Allosteric Mechanism that Stabilizes a Ternary Complex
Davila-Calderon, J.; Patwardhan, N. N.; Chiu, L.-Y.; Sugarman, A. L.; Cai, Z.; Penutmutchu, S. R.; Li, M.-L.; Brewer, G.; Hargrove, A. E.; Tolbert, B. S.
10.1101/2020.03.10.981167 — biochemistry — Posted on 2020-03-11
2694 VarStack: a Web Tool for Data Retrieval to Interpret Somatic Variants in Cancer
Howard, M. F.; Kane, B.; Lepry, M.; Stey, P.; Ragavendran, A.; Gamsiz Uzun, E. D.
10.1101/2020.03.10.985952 — bioinformatics — Posted on 2020-03-11
2695 Machine learning approaches reveal genomic regions associated with sugarcane brown rust resistance
Aono, A. H.; Costa, E. A.; Rody, H. V. S.; Nagai, J. S.; Pimenta, R. J. G.; Mancini, M. C.; dos Santos, F. R. C.; Pinto, L. R.; Landell, M. G. d. A.; de Souza, A. P.; Kuroshu, R. M.
10.1101/2020.03.10.985960 — bioinformatics — Posted on 2020-03-11
2698 rePROBE: Workflow for Revised Probe Assignment and Updated Probe-Set Annotation in Microarrays
Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Murani, E.; Ponsuksili, S.; Wimmers, K.
10.1101/2020.03.10.985119 — bioinformatics — Posted on 2020-03-11
2700 Single cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia
Zheng, J.; Ru, W.; Adolacion, J. R.; Spurgat, M. S.; Liu, X.; Yuan, S.; Liang, R. X.; Dong, J.; Potter, A.; Potter, S. S.; Varadarajan, N.; Tang, S.-J.
10.1101/2020.03.10.985895 — neuroscience — Posted on 2020-03-11
2703 Filamentous Bacteriophage Delay Healing of Pseudomonas-Infected Wounds
Bach, M. S.; de Vries, C. R.; Sweere, J. M.; Popescu, M.; Van Belleghem, J. D.; Kaber, G.; Burgener, E. B.; Liu, D.; Tran, Q.-L.; Dharmaraj, T.; Birukova, M.; Sunkari, V.; Balaji, S.; Keswani, S.; Banaei, N.; Khona, D. K.; Nedelec, L.; Sen, C. K.; Chandra, V.; Secor, P. R.; Suh, G. A.; Bollyky, P. L.
10.1101/2020.03.10.985663 — microbiology — Posted on 2020-03-11
2704 ZENITH: A flow cytometry based method for functional profiling energy metabolism with single cell resolution
ARGUELLO, R. J.; COMBES, A. J.; CHAR, R.; BOUSIQUOT, E.; GIGAN, J. P.; CAMOSSETO, V.; SAMAD, B.; TSUI, J.; YAN, P.; BOISSONNEAU, S.; FIGARELLA-BRANGER, D.; TABOURET, E.; GATTI, E.; Krummel, M. F.; PIERRE, P.
10.1101/2020.03.10.985796 — immunology — Posted on 2020-03-11
2709 Belowground changes to community structure alter methane-cycling dynamics in Amazonia
Meyer, K. M.; Morris, A.; Webster, K.; Klein, A. M.; Kroeger, M. E.; Meredith, L.; Braendholt, A.; Nakamura, F.; Venturini, A.; Fonseca de Souza, L.; Shek, K. L.; Danielson, R.; Van Haren, J.; Barbosa de Camargo, P.; Tsai, S. M.; Dini-Andreote, F.; de Mauro, J. M. S.; Nusslein, K.; Saleska, S.; Rodrigues, J. L. M.; Bohannan, B. J. M.
10.1101/2020.03.10.984807 — ecology — Posted on 2020-03-11
2710 Non-canonical open reading frames encode functional proteins essential for cancer cell survival
Prensner, J. R.; Enache, O. M.; Luria, V.; Krug, K.; Clauser, K. R.; Dempster, J. M.; Karger, A.; Wang, L.; Stumbraite, K.; Wang, V. M.; Botta, G.; Lyons, N. J.; Goodale, A.; Kalani, Z.; Fritchman, B.; Brown, A.; Alan, D.; Green, T.; Yang, X.; Jaffe, J. D.; Roth, J. A.; Piccioni, F.; Kirschner, M. W.; Ji, Z.; Root, D. E.; Golub, T. R.
10.1101/2020.03.10.981001 — cancer biology — Posted on 2020-03-11
2712 Controlling the Growth of the Skin Commensal Staphylococcus epidermidis Using D-Alanine Auxotrophy
Whitfill, T. M.; Dodds, D.; Bose, J. L.; Dong, M.-D.; Dube, G.; Grossman, T.; Kaiser, A.; Kulkarni, K.; Leger, R.; Mootien-Boyd, S.; Munivar, A.; Oh, J.; Pestrak, M.; Rajpura, K.; Tikhonov, A.; Turecek, T.
10.1101/2020.03.10.985911 — microbiology — Posted on 2020-03-11
2713 The Demographic History of Micro-endemics: Have Rare Species Always Been Rare?
Helmstetter, A. J.; Cable, S.; Rakotonasolo, F.; Rabarijaona, R.; Rakotoarinivo, M.; Eiserhardt, W. L.; Baker, W. J.; Papadopulos, A. S. T.
10.1101/2020.03.10.985853 — evolutionary biology — Posted on 2020-03-11
2715 Complete genome sequence and analysis of nine Egyptian females with clinical information from different geographic regions in Egypt
ElHefnawi, M.; Hegazy, E.; ElFiky, A.; Jeon, Y.; Jeon, S.; Bhak, J.; Metwally, F.; Sugano, S.; Horiuchi, T.; Kazumi, A.; Blazyte, A.
10.1101/2020.03.10.985317 — bioinformatics — Posted on 2020-03-11
2719 Inhibition and down regulation of the serotonin transporter contribute to the progression of degenerative mitral regurgitation
Levy, R. J.; Fitzpatrick, E.; Castillero, E.; Shukla,, H. J.; Inamdar,, V. V.; Aghali, A. E.; Grau, J. B.; Rioux, N.; Salvati, E.; Keeney, S. J.; Nissim, I.; Gorman, R. C. C.; Rauova, L.; Stachelek, S. J.; Brown, C. R.; Krieger, A. M.; Ferrari, G.
10.1101/2020.03.10.985382 — physiology — Posted on 2020-03-11
2721 Ventral tegmental dopamine neurons control the impulse vector during motivated behavior
Hughes, R.; Bakhurin, K.; Petter, E.; Watson, G.; Kim, N.; Friedman, A.; Yin, H.
10.1101/2020.03.10.985879 — neuroscience — Posted on 2020-03-11
2722 Subventricular zone adult mouse neural stem cells and human glioblastoma stem cells require insulin receptor for self-renewal
Chidambaram, S.; Rothbard, D.; Deshpande, K.; Cajuste, Y.; Fiser, A.; Snyder, K.; Farjardo, E.; Tapinos, N.; Wood, T. L.; Levison, S. W.
10.1101/2020.03.10.985598 — neuroscience — Posted on 2020-03-11
2723 Gamma activity accelerates during prefrontal development
Bitzenhofer, S. H.; Poepplau, J. A.; Hanganu-Opatz, I. L.
10.1101/2020.03.10.986281 — neuroscience — Posted on 2020-03-11
2724 Groucho/TLE opposes axial to hypaxial motor neuron development
Salin-Cantegrel, A.; Dali, R.; Wang, J. W.; Beaulieu, M.; Deshmukh, M.; Tang, Y. M.; Stifani, S.
10.1101/2020.03.10.986323 — neuroscience — Posted on 2020-03-11
2728 Amplitude Analysis of Polarization Modulation Data and 3D-Polarization Demodulation (3D-SPoD)
Albrecht, A.; Pfennig, D.; Nowak, J.; Matis, R.; Schaks, M.; Hafi, N.; Rottner, K.; Walla, P. J.
10.1101/2020.03.10.986034 — biophysics — Posted on 2020-03-11
2731 Aging increases the systemic molecular degree of inflammatory perturbation in patients with tuberculosis
Oliveira-de-Souza, D.; Vinhaes, C. L.; Arriaga, M. B.; Pavan Kumar, N.; Queiroz, A. T. L.; Fukutani, K. F.; Babu, S.; Andrade, B. B.
10.1101/2020.03.10.985697 — immunology — Posted on 2020-03-11
2732 Moderate early-life stress improves adult zebrafish (Danio rerio) spatial short-term memory but does not affect social and anxiety-like responses
Dotto Fontana, B.; J. Gibbon, A.; Cleal, M.; Sudwarts, A.; Pritchett, D.; Miletto Petrazzini, M. E.; H Brennan, C.; Parker, M. O.
10.1101/2020.03.10.985945 — animal behavior and cognition — Posted on 2020-03-11
2735 Genome assembly and annotation of Macadamia tetraphylla
Niu, Y.-F.; Li, G.-H.; Ni, S.-B.; He, X.-Y.; Zheng, C.; Liu, Z.-Y.; Gong, L.-D.; Kong, G.-H.; Liu, J.
10.1101/2020.03.11.987057 — genomics — Posted on 2020-03-11
2736 Endogenous retroviruses drive species-specific germline transcriptomes in mammals
Sakashita, A.; Maezawa, S.; Alavattam, K. G.; Yukawa, M.; Barski, A.; Pavlicev, M.; Namekawa, S. H.
10.1101/2020.03.11.987230 — developmental biology — Posted on 2020-03-11
2738 Multiple midfrontal thetas revealed by sourceseparation of simultaneous MEG and EEG
Zuure, M. B.; Hinkley, L.; Tiesinga, P. H. E.; Nagarajan, S. S.; Cohen, M. X.
10.1101/2020.03.11.987040 — neuroscience — Posted on 2020-03-11
2739 Inhibition of KDM1A activity restores adult neurogenesis and improves hippocampal memory in a mouse model of Kabuki syndrome
Zhang, L.; Pilarowski, G. O.; Pich, E. M.; Nakatani, A.; Dunlop, J.; Baba, R.; Matsuda, S.; Daini, M.; Hattori, Y.; Matsumoto, S.; Ito, M.; Kimura, H.; Bjornsson, H. T.
10.1101/2020.03.11.986976 — genetics — Posted on 2020-03-11
2743 Super-enhancer switching drives a burst in germline gene expression at the mitosis-to-meiosis transition
Maezawa, S.; Yukawa, M.; Chen, X.; Sakashita, A.; Alavattam, K. G.; Weirauch, M. T.; Barski, A.; Namekawa, S. H.
10.1101/2020.03.11.987180 — developmental biology — Posted on 2020-03-11
2746 Genome-wide data inferring the evolution and population demography of the novel pneumonia coronavirus (SARS-CoV-2)
Fang, B.; Liu, L.; Yu, X.; Li, X.; Ye, G.; Xu, J.; Zhang, L.; Zhan, F.; Liu, G.; Pan, T.; Shu, Y.; Jiang, Y.
10.1101/2020.03.04.976662 — evolutionary biology — Posted on 2020-03-11
2747 Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites
Kang, S.; Yang, M.; Hong, Z.; Zhang, L.; Huang, Z.; Chen, X.; He, S.; Zhou, Z.; Zhou, Z.; Chen, Q.; Yan, Y.; Zhang, C.; Shan, H.; Chen, S.
10.1101/2020.03.06.977876 — molecular biology — Posted on 2020-03-11
2748 A novel bat coronavirus reveals natural insertions at the S1/S2 cleavage site of the Spike protein and a possible recombinant origin of HCoV-19
Zhou, H.; Chen, X.; Hu, T.; Li, J.; Song, H.; Liu, Y.; Wang, P.; Liu, D.; Yang, J.; Holmes, E. C.; Hughes, A. C.; Bi, Y.; Shi, W.
10.1101/2020.03.02.974139 — microbiology — Posted on 2020-03-11
2749 Cerebellar Purkinje cells can differentially modulate coherence between sensory and motor cortex depending on region and behavior
Lindeman, S.; Kros, L.; Hong, S.; Mejias, J. F.; Romano, V.; Negrello, M.; Bosman, L. W.; De Zeeuw, C. I.
10.1101/2020.03.11.986943 — neuroscience — Posted on 2020-03-11
2750 Enhanced activity of glycolytic enzymes in Drosophila and human cell models of Parkinson's disease based on DJ-1 deficiency
Solana-Manrique, C.; Sanz, F. J.; Ripollés, E.; Banó, M. C.; Munoz-Soriano, V.; Torres, J.; Paricio, N.
10.1101/2020.03.10.985135 — neuroscience — Posted on 2020-03-11
2751 Dissecting the role of Amerindian genetic ancestry and ApoE ε4 allele on Alzheimer disease in an admixed Peruvian population
Cornejo-Olivas, M.; Rajabli, F.; Marca Ysbel, M. V.; Whitehead, P. G.; Ortega Davilla, G. O.; Hofmann, N. K.; Milla-Neyra, A. K.; Veliz-Otani, D. M.; Custodio, N.; Montesinos, R.; Castro-Suarez, S.; Meza-Vega, M.; Adams, L. D.; Mena, P. R.; Isasi, R.; Cuccaro, M. L.; Vance, J. M.; Beecham, G. W.; Mazzetti Soler, P. E.; Pericak-Vance, M. A.
10.1101/2020.03.10.985846 — genetics — Posted on 2020-03-11
2752 An improved hgcAB primer set and direct high throughput sequencing expand Hg-methylator diversity in nature
Gionfriddo, C. M.; Wymore, A. M.; Jones, D. S.; Wilpiszeski, R. L.; Lynes, M. M.; Christensen, G. A.; Soren, A.; Gilmour, C. C.; Podar, M.; Elias, D.
10.1101/2020.03.10.983866 — molecular biology — Posted on 2020-03-11
2753 Linkage Analysis in Caribbean Hispanic Families with Puerto Rican Ancestry Idenitfies an Alzheimer Disease Locus on chromosome 9.
Rajabli, F.; Feliciano-Astacio, B. E.; Cukier, H. N.; Wang, L.; Griswold, A.; Hamilton-Nelson, K. L.; Adams, L. D.; Rodriguez, V. C.; Mena, P. R.; Tejada, S.; Celis, K.; Whitehead, P. G.; Van Booven, D. J.; Hofmann, N. K.; Bussies, P.; Prough, M.; Chinea, A.; Feliciano, N. I.; Acosta, H.; Dalgard, C. L.; Vance, J. M.; Cuccaro, M. C.; Beecham, G. W.; Pericak-Vance, M. A.
10.1101/2020.03.10.986083 — genetics — Posted on 2020-03-11
2756 Cytotoxic activity of CD4 T Cells during the early stage of autoimmune neuroinflammation
Farias, A. S.; Pradella, F.; Boldrini, V. O.; Marques, A. M.; Morais, G. D.; Francelin, C.; Cocenza, R. S.; Lima, V. C.; Bonora-Jr, M.; Brunetti, N. S.; Campos, B. B.; Fonseca, E. S. M.; Rocha-Parise, M.; Stella, C. R. V.; Damasceno, A.; von Glehn, F.; Longhini, A. L.; Santos, L. M. B.
10.1101/2020.03.10.985614 — immunology — Posted on 2020-03-11
2757 Cell wall remodeling and vesicle trafficking mediate the root clock in Arabidopsis
Wachsman, G.; Zhang, J.; Moreno-Risueno, M. A.; Anderson, C. T.; Benfey, P. N.
10.1101/2020.03.10.985747 — plant biology — Posted on 2020-03-11
2759 Engineered IL-10 variants elicit potent immuno-modulatory activities at therapeutic low ligand doses
Gorby, C.; Sotolongo Bellon, J.; Wilmes, S.; Warda, W.; Pohler, E.; Fyfe, P.; Cozzani, A.; FERRAND, C.; Walter, M.; MITRA, S.; Piehler, J.; Moraga, I.
10.1101/2020.03.10.985069 — immunology — Posted on 2020-03-11
2762 First complete genome sequences of Streptococcus pyogenes NCTC 8198T and CCUG 4207T, the type strain of the type species of the genus Streptococcus: 100% match in length and sequence identity between PacBio solo and Illumina plus Oxford Nanopore hybrid assemblies
Salva-Serra, F.; Jaen-Luchoro, D.; Jakobsson, H. E.; Gonzales-Siles, L.; Karlsson, R.; Busquets, A.; Gomila, M.; Bennasar-Figueras, A.; Russell, J. E.; Abbas Fazal, M.; Alexander, S.; Moore, E. R. B.
10.1101/2020.03.10.985267 — microbiology — Posted on 2020-03-11
2763 Nonalcoholic fatty liver disease is associated with decreased hepatocyte mitochondrial respiration but not mitochondrial number
Sinton, M. C.; Meseguer-Ripolles, J.; Lucendo-Villarin, B.; Lyall, M. J.; Carter, R. N.; Morton, N. M.; Hay, D. C.; Drake, A.
10.1101/2020.03.10.985200 — biochemistry — Posted on 2020-03-11
2766 The murine Microenvironment Cell Population counter method to estimate abundance of tissue-infiltrating immune and stromal cell populations in murine samples using gene expression
Petitprez, F.; Levy, S.; Sun, C.-M.; Meylan, M.; Linhard, C.; Becht, E.; Elarouci, N.; Roumenina, L. T.; Ayadi, M.; Sautes-Fridman, C.; Fridman, W. H.; de Reynies, A.
10.1101/2020.03.10.985176 — bioinformatics — Posted on 2020-03-11
2771 The chromatin remodeler LSH controls genome-wide cytosine hydroxymethylation
de Dieuleveult, M.; Bizet, M.; Colin, L.; Calonne, E.; Bachman, M.; Li, C.; Stancheva, I.; Fuks, F.; Deplus, R.
10.1101/2020.03.10.983148 — molecular biology — Posted on 2020-03-11
2774 Dopamine pathway characterization during the reproductive mode switch in the pea aphid
LE TRIONNAIRE, G.; HUDAVERDIAN, S.; RICHARD, G.; TANGUY, S.; GLEONNEC, F.; PRUNIER-LETERME, N.; GAUTHIER, J.-P.; TAGU, D.
10.1101/2020.03.10.984989 — developmental biology — Posted on 2020-03-11
2775 MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas
Oldrini, B.; Vaquero-Siguero, N.; Mu, Q.; Kroon, P.; Zhang, Y.; Galan-Ganga, M.; Bao, Z.; Wang, Z.; Liu, H.; Sa, J. K.; Zhao, J.; Kim, H.; Rodriguez-Perales, S.; Nam, D.-H.; Verhaak, R. G.; Rabadan, R.; Jiang, T.; Wang, J.; Squatrito, M.
10.1101/2020.03.10.985226 — cancer biology — Posted on 2020-03-11
2776 Rapid growth and fusion of protocells in surface-adhered membrane networks
Koksal, E. S.; Liese, S.; Xue, L.; Ryskulov, R.; Viitala, L.; Carlson, A.; Gozen, I.
10.1101/2020.03.10.980417 — biophysics — Posted on 2020-03-11
2779 Transcriptional repression of Myc underlies AGO1's tumour suppressor function
Zaytseva, O.; Mitchell, N. C.; Guo, L.; Marshall, O.; Parsons, L. M.; Hannan, R. D.; Levens, D. L.; Quinn, L. M.
10.1101/2020.03.10.984906 — developmental biology — Posted on 2020-03-11
2782 A quasi-paired cohort strategy reveals the impaired detoxifying function of microbes in the gut of autistic children
Zhang, M.; Chu, Y.; Meng, Q.; Ding, R.; Shi, X.; Wang, Z.; He, Y.; Zhang, J.; Liu, J.; Zhang, J.; Yu, J.; Kang, Y.; Wang, J.
10.1101/2020.03.10.984872 — microbiology — Posted on 2020-03-11
2783 Ancient and modern genomes reveal microsatellites maintain a dynamic equilibrium through deep time
McComish, B. J.; Charleston, M. A.; Parks, M.; Baroni, C.; Salvatore, M. C.; Li, R.; Zhang, G.; Millar, C. D.; Holland, B.; Lambert, D. M.
10.1101/2020.03.09.972364 — evolutionary biology — Posted on 2020-03-11
2784 The demographic decline of a sea lion population followed multi-decadal sea surface warming
Adame, K.; Elorriaga-Verplancken, F. R.; Beier, E.; Acevedo-Whitehouse, K.; Pardo, M. A.
10.1101/2020.03.09.984716 — ecology — Posted on 2020-03-11
2788 Nucleo-plastidic PAP8/pTAC6 couples chloroplast formation with photomorphogenesis
Liebers, M.; Gillet, F.-X.; Israel, a.; Pounot, K.; Chambon, L.; Chieb, M.; Chevalier, F.; Ruedas, R.; Favier, A.; Gans, P.; Boeri-Erba, E.; Cobessi, D.; Pfannschmidt, T.; Blanvillain, R.
10.1101/2020.03.10.985002 — plant biology — Posted on 2020-03-11
2790 The effect of acute sleep deprivation on skeletal muscle protein synthesis and the hormonal environment
Lamon, S.; Morabito, A.; Arentson-Lantz, E. J.; Knowles, O.; Vincent, G. E.; Condo, D.; Alexander, S. E.; Garnham, A.; Paddon-Jones, D. J.; Aisbett, B.
10.1101/2020.03.09.984666 — physiology — Posted on 2020-03-11
2791 Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33.
Schumacher, M. A.; Hsieh, J. J.; Liu, C. Y.; Appel, K. L.; Waddell, A.; Almohazey, D.; Katada, K.; Bernard, J. K.; Bucar, E. B.; Gadeock, S.; Maselli, K. M.; Washington, M. K.; Grikscheit, T. C.; Warburton, D.; Rosen, M. J.; Frey, M. R.
10.1101/2020.03.09.984369 — physiology — Posted on 2020-03-11
2794 Evidence for non-methanogenic metabolisms in globally distributed archaeal clades basal to the Methanomassiliicoccales
Zinke, L. A.; Evans, P. N.; Schroeder, A.; Parks, D. H.; Varner, R. K.; Rich, V.; Tyson, G.; Emerson, J. B.
10.1101/2020.03.09.984617 — microbiology — Posted on 2020-03-11
2795 Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Endosomal Sensing by Dendritic Cells in Psoriasis
Lou, F.; Sun, Y.; Xu, Z.; Niu, L.; Wang, Z.; Deng, S.; Liu, Z.; Zhou, H.; Bai, J.; Yin, Q.; Cai, X.; Sun, L.; Wang, H.; Wu, Z.; Chen, X.; Shi, Y.; Tao, W.; Ginhoux, F.; Wang, H.
10.1101/2020.03.09.984658 — immunology — Posted on 2020-03-11
2796 Increased APOEϵ4 expression is associated with reactive A1 astrocytes and the difference in Alzheimer Disease risk from diverse ancestral backgrounds
Griswold, A. J.; Celis, K.; Bussies, P.; Rajabli, F.; Whitehead, P.; Hamilton-Nelson, K.; Beecham, G. W.; Dykxhoorn, D. M.; Nuytemans, K.; Wang, L.; Gardner, O. K.; Dorfsman, D.; Bigio, E. H.; Mesulam, M.-M.; Weintraub, S.; Geula, C.; Gearing, M.; Martinez-McGrath, E.; Dalgard, C. L.; Scott, W. K.; Haines, J. L.; Pericak-Vance, M. A.; Young, J. I.; Vance, J. M.
10.1101/2020.03.09.983817 — genomics — Posted on 2020-03-11
2797 A new genome allows the identification of genes associated with natural variation in aluminium tolerance in Brachiaria grasses
Worthington, M.; Perez, J. G.; Mussurova, S.; Silva-Cordoba, A.; Castiblanco, V.; Jones, C.; Fernandez-Fuentes, N.; Skot, L.; Dyer, S.; Tohme, J.; Di Palma, F.; Arango, J.; Armstead, I.; De Vega, J. J.
10.1101/843870 — genomics — Posted on 2020-03-11
2798 Effects-sizes of deletions and duplications on autism risk across the genome
Douard, E.; Zeribi, A.; Schramm, C.; Tamer, P.; Loum, M. A.; Nowak, S.; Saci, Z.; Lord, M.-P.; Rodriguez-Herreros, B.; Jean-Louis, M.; MOREAU, C.; Loth, E.; Schumann, G.; Pausova, Z.; Elsabbagh, M.; Almasy, L.; Glahn, D. C.; Bourgeron, T.; Labbe, A.; Paus, T.; Mottron, L.; Greenwood, C. M.; Huguet, G.; Jacquemont, S.
10.1101/2020.03.09.979815 — genetics — Posted on 2020-03-11
2803 Diverse homeostatic and immunomodulatory roles of immune cells in the developing mouse lung revealed at single cell resolution
Domingo-Gonzalez, R.; Zanini, F.; Che, X.; Liu, M.; Jones, R. C.; Swift, M. A.; Quake, S. R.; Cornfield, D. N.; Alvira, C. M.
10.1101/2020.02.10.942359 — developmental biology — Posted on 2020-03-11
2804 DIP/Dpr interactions and the evolutionary design of specificity in protein families
Sergeeva, A. P.; Katsamba, P. S.; Cosmanescu, F.; Brewer, J. J.; Ahlsen, G.; Mannepalli, S.; Shapiro, L.; Honig, B.
10.1101/2020.01.13.899120 — biophysics — Posted on 2020-03-11
2805 A simple, scalable approach to building a cross-platform transcriptome atlas
Angel, P. W.; Rajab, N.; Deng, Y.; Pacheco, C. M.; Chen, T.; Le Cao, K.-A.; Choi, J.; Wells, C.
10.1101/2020.03.09.984468 — bioinformatics — Posted on 2020-03-11
2806 Stiffness of Nanoparticulate Mineralized Collagen Scaffolds Triggers Osteogenesis via Mechanotransduction and Canonical Wnt Signaling
Zhou, Q.; Lyu, S.; Bertrand, A. A.; Hu, A. C.; Chan, C. H.; Ren, X.; Dewey, M. J.; Tiffany, A. S.; Harley, B. A.; Lee, J. C.
10.1101/2020.03.09.982231 — bioengineering — Posted on 2020-03-11
2809 Mechanisms of γ-Secretase Activation and Substrate Processing
Bhattarai, A.; Devkota, S.; Bhattarai, S.; Wolfe, M. S.; Miao, Y.
10.1101/2020.03.09.984534 — biochemistry — Posted on 2020-03-11
2813 Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis
Guillotin, D.; Taylor, A.; Plate, M.; Mercer, P.; Edwards, L.; Haggart, R.; Miele, G.; McAnulty, R.; Maher, T.; Hynds, R. E.; Jamal-Hanjani, M.; Marshall, R.; Fisher, A.; Blanchard, A.; Chambers, R.
10.1101/2020.03.10.984955 — cell biology — Posted on 2020-03-11
2814 CryoSIM: super resolution 3D structured illumination cryogenic fluorescence microscopy for correlated ultra-structural imaging
Phillips, M. A.; Harkiolaki, M.; Pinto, D. M. S.; Parton, R. M.; Palanca, A.; Garcia-Moreno, M.; Sedat, J.; Stuart, D. I.; Castello, A.; Booth, M. J.; Davis, I.; Dobbie, I. M.
10.1101/2020.03.09.980334 — cell biology — Posted on 2020-03-11
2815 Evidence for Similar Structural Brain Anomalies in Youth and Adult Attention-Deficit/Hyperactivity Disorder: A Machine Learning Analysis
Zhang-James, Y.; Helminen, E.; Liu, J.; The ENIGMA-ADHD Working Group, ; Franke, B.; Hoogman, M.; Faraone, S. V.
10.1101/546671 — bioinformatics — Posted on 2020-03-11
2816 Designing Peptides on a Quantum Computer
Mulligan, V. K.; Melo, H.; Merritt, H. I.; Slocum, S.; Weitzner, B. D.; Watkins, A. M.; Renfrew, P. D.; Pelissier, C.; Arora, P. S.; Bonneau, R.
10.1101/752485 — bioengineering — Posted on 2020-03-11
2818 Primary myeloid cell proteomics and transcriptomics: importance of β tubulin isotypes for osteoclast function.
Guerit, D.; Marie, P.; Morel, A.; Maurin, J.; Verollet, C.; Raynaud-Messina, B.; Urbach, S.; BLANGY, A.
10.1101/800516 — cell biology — Posted on 2020-03-11
2820 Mitochondrial DNA Copy Number (mtDNA-CN) Can Influence Mortality and Cardiovascular Disease via Methylation of Nuclear DNA CpGs
Castellani, C. A.; Longchamps, R. J.; Sumpter, J. A.; Newcomb, C. E.; Lane, J. A.; Grove, M. L.; Bressler, J.; Brody, J. A.; Floyd, J. S.; Bartz, T. M.; Taylor, K. D.; Wang, P.; Tin, A.; Coresh, J.; Pankow, J. S.; Fornage, M.; Guallar, E.; O'Rourke, B.; Pankratz, N.; Liu, C.; Levy, D.; Sotoodehnia, N.; Boerwinkle, E.; Arking, D. E.
10.1101/673293 — genomics — Posted on 2020-03-11
2821 A limited set of transcriptional programs define major cell types
Breschi, A.; Munoz-Aguirre, M.; Wucher, V.; Davis, C. A.; Garrido-Martin, D.; Djebali, S.; Gillis, J.; Pervouchine, D. D.; Vlasova, A.; Dobin, A.; Zaleski, C.; Drenkow, J.; Danyko, C.; Scavelli, A.; Reverter, F.; Snyder, M. P.; Gingeras, T. R.; Guigo, R.
10.1101/857169 — genomics — Posted on 2020-03-11
2822 Embryo-like features in developing Bacillus subtilis biofilms
Futo, M.; Opasic, L.; Koska, S.; Corak, N.; Siroki, T.; Ravikumar, V.; Thorsell, A.; Kifer, D.; Domazet-Loso, M.; Vlahovicek, K.; Mijakovic, I.; Domazet-Loso, T.
10.1101/2020.03.09.983718 — evolutionary biology — Posted on 2020-03-11
2823 Metabolic rules of microbial community assembly
Estrela, S.; Vila, J. C.; Lu, N.; Bajic, D.; Rebolleda-Gomez, M.; Chang, C.-Y.; Sanchez, A.
10.1101/2020.03.09.984278 — ecology — Posted on 2020-03-11
2824 Sister-chromatid-sensitive Hi-C reveals the conformation of replicated human chromosomes
Mitter, M.; Gasser, C.; Takacs, Z.; Langer, C. H. C.; Tang, W.; Jessberger, G.; Beales, C. T.; Neuner, E.; Ameres, S. L.; Peters, J.-M.; Goloborodko, A.; Micura, R.; Gerlich, D. W.
10.1101/2020.03.10.978148 — cell biology — Posted on 2020-03-11
2826 Comparison of visualisation tools for single-cell RNAseq data
Cakir, B.; Prete, M.; Huang, N.; van Dongen, S.; Pir, P.; Kiselev, V. Y.
10.1101/2020.01.24.918342 — bioinformatics — Posted on 2020-03-11
2828 Comparing quality of reporting between preprints and peer-reviewed articles in the biomedical literature
Carneiro, C. F. D.; Queiroz, V. G. S.; Moulin, T. C.; Carvalho, C. A. M.; Haas, C. B.; Rayee, D.; Henshall, D. E.; De-Souza, E. A.; Amorim, F. E.; Boos, F. Z.; Guercio, G. D.; Costa, I. R.; Hajdu, K. L.; van Egmond, L.; Modrak, M.; Tan, P. B.; Abdill, R. J.; Burgess, S. J.; Guerra, S. F. S.; Bortoluzzi, V. T.; Amaral, O. B.
10.1101/581892 — scientific communication and education — Posted on 2020-03-11
2830 Genuine cross-frequency coupling networks in human resting-state electrophysiological recordings
Siebenhuehner, F.; Wang, S. H.; Arnulfo, G.; Lampinen, A.; Nobili, L.; Palva, J. M.; Palva, S.
10.1101/547638 — neuroscience — Posted on 2020-03-11
2833 TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control
Douse, C. H.; Tchasovnikarova, I. A.; Timms, R. T.; Protasio, A. V.; Seczynska, M.; Prigozhin, D. M.; Albecka, A.; Wagstaff, J.; Williamson, J. C.; Freund, S. M.; Lehner, P. J.; Modis, Y.
10.1101/2020.03.09.974832 — molecular biology — Posted on 2020-03-11
2834 Association of lanthipeptide genes with TnpAREP transposases in marine picocyanobacteria
Laurenceau, R.; Raho, N.; Cariani, Z.; Bliem, C.; Osman, M. A. M.; Chisholm, S. W.
10.1101/2020.03.09.984088 — microbiology — Posted on 2020-03-11
2835 Reciprocal transplant experiment reveals partial functional redundancy in the aquatic microbiome
Tandon, K.; Wan, M.-T.; Yang, C.-C.; Yang, S.-H.; Baatar, B.; Chiu, C.-Y.; Tsai, J.-W.; Liu, W.-C.; Ng, C. S.; Tang, S.-L.
10.1101/2020.02.01.930198 — ecology — Posted on 2020-03-11
2839 Parallel accumulation - serial fragmentation combined with data-independent acquisition (diaPASEF): Bottom-up proteomics with near optimal ion usage
Meier, F.; Brunner, A.-D.; Frank, M.; Ha, A.; Bludau, I.; Voytik, E.; Kaspar-Schoenefeld, S.; Lubeck, M.; Raether, O.; Aebersold, R.; Collins, B. C.; Rost, H. L.; Mann, M.
10.1101/656207 — systems biology — Posted on 2020-03-11
2840 Cell assemblies in the cortico-hippocampal-reuniens network during slow oscillations
Angulo-Garcia, D.; Ferraris, M.; Ghestem, A.; Nallet-Khosrofian, L.; Bernard, C.; Quilichini, P. P.
10.1101/474973 — neuroscience — Posted on 2020-03-11
2843 Metagenomic Insights into Microbial Metabolisms of a Sulfur-Influenced Glacial Ecosystem
Trivedi, C. B.; Stamps, B. W.; Lau, G. E.; Grasby, S. E.; Templeton, A.; Spear, J. R.
10.1101/2020.01.31.929786 — microbiology — Posted on 2020-03-11
2844 Detailed analysis of public RNAseq data and longnon-coding RNA: a proposed enhancement to mesenchymalstem cell characterisation
RIQUIER, S.; MATHIEU, M.; BOUREUX, A.; RUFFLE, F.; LEMAITRE, J.-M.; Djouad, F.; GILBERT, N.; COMMES, T.
10.1101/2020.03.09.976001 — genomics — Posted on 2020-03-11
2845 Genomic analysis of European Drosophila populations reveals major longitudinal structure, continent-wide selection, and unknown DNA viruses
Kapun, M.; Barron Aduriz, M. G.; Staubach, F.; Obbard, D.; Wiberg, R. A. W.; Vieira, J.; Goubert, C.; Rota Stabelli, O.; Kankare, M.; Bogaerts-Marquez, M.; Haudry, A.; Waidele, L.; Kozeretska, I.; Pasyukova, E.; Loeschcke, V.; Pascual, M.; Vieira, C. P.; Serga, S.; Montchamp-Moreau, C.; Abbott, J.; Gibert, P.; Porcelli, D.; Posnien, N.; Sanchez-Gracia, A.; Grath, S.; Sucena, E.; Bergland, A.; Garcia Guerreiro, M. P.; Onder, B. S.; Argyridou, E.; Guio, L.; Schou, M. F.; Deplancke, B.; Vieira, C.; Ritchie, M. G.; Zwaan, B.; Tauber, E.; Orengo, D.; Puerma, E.; Aguade, M.; Schmidt, P.; Parsch, J.;
10.1101/313759 — evolutionary biology — Posted on 2020-03-11
2847 γ-H2AX is present at mouse meiotic kinetochores
Guajardo, A.; Viera, A.; Parra, M. T.; Martinez Valdivia, M. J.; Rufas, J. S.; Suja, J. A.
10.1101/2020.03.10.986273 — cell biology — Posted on 2020-03-11
2848 Biophysical forces rewire cell metabolism to guide microtubule-dependent cell mechanics
TORRINO, S.; Audebert, S.; BELHADJ, I.; LACOUX, C.; ABELANET, S.; BRAU, F.; PISANO, S.; CHAN, S. Y.; MARI, B.; Oldham, W. M.; BERTERO, T.
10.1101/2020.03.10.985036 — cell biology — Posted on 2020-03-11
2849 A PEROXO-Tag enables rapid isolation of peroxisomes from human cells
Ray, G. J.; Boydston, E. A.; Shortt, E.; Wyant, G. A.; Lourido, S.; Chen, W. W.; Sabatini, D. M.
10.1101/2020.03.10.984948 — cell biology — Posted on 2020-03-11
2850 Id proteins promote a cancer stem cell phenotype in triple negative breast cancer via negative regulation of Robo1
Teo, W. S.; Holliday, H.; Karthikeyan, N.; Cazet, A. S.; Roden, D. L.; Harvey, K.; Konrad, C. V.; Murali, R.; Varghese, B. A.; T., A. P.; Chan, C.-L.; McFarland, A.; Junankar, S.; Ye, S.; Yang, J.; Nikolic, I.; Shah, J. S.; Baker, L. A.; Millar, E. K. A.; Naylor, M. J.; Ormandy, C. J.; Lakhani, S. R.; Kaplan, W.; Mellick, A. S.; O'Toole, S. A.; Swarbrick, A.; Nair, R.
10.1101/497313 — cancer biology — Posted on 2020-03-11
2851 Co-expression of calcium channels and delayed rectifier potassium channels protects the heart from proarrhythmic events
Ballouz, S.; Mangala, M. M.; Perry, M. D.; Heitmann, S.; Gillis, J. A.; Hill, A. P.; Vandenberg, J. I.
10.1101/659821 — biophysics — Posted on 2020-03-11
2852 Insulin-like Growth Factor-1 Regulates the Mechanosensitivity of Chondrocytes by Modulating TRPV4
Trompeter, N. S.; Gardinier, J. D.; DeBarros, V. M.; Boggs, M.; Hurd, L.; Duncan, R. L.
10.1101/2020.03.10.985713 — cell biology — Posted on 2020-03-11
2853 TimeTeller: a New Tool for Precision Circadian Medicine and Cancer Prognosis
Vlachou, D.; Bjarnason, G. A.; Giacchetti, S.; Levi, F.; Rand, D. A.
10.1101/622050 — cancer biology — Posted on 2020-03-11
2854 Macrophages utilize a bet-hedging strategy for antimicrobial activity in phagolysosomal acidification
Dragotakes, Q.; Stouffer, K.; Fu, M. S.; Sella, Y.; Youn, C.; Yoon, I.; Leon-Rodriguez, C. M.; Freij, J. B.; Bergman, A.; Casadevall, A.
10.1101/470617 — microbiology — Posted on 2020-03-11
2855 Engineered Heterochronic Parabiosis in 3D Microphysiological System for Identification of Muscle Rejuvenating Factors
Lee, Y.; Choi, J. J.; Ahn, S. I.; Lee, N. H.; Han, W. M.; Mohiuddin, M.; Shin, E. J.; Wood, L. B.; Park, K. D.; Kim, Y.; Jang, Y. C.
10.1101/2020.03.10.975482 — cell biology — Posted on 2020-03-11
2856 High-Throughput Image Analysis of Lipid-Droplet-Bound Mitochondria
Miller, N.; Wolf, D.; Alsabeeh, N.; Mahdaviani, K.; Segawa, M.; Liesa, M.; Shirihai, O. S.
10.1101/2020.03.10.985929 — cell biology — Posted on 2020-03-11
2857 Unravelling the phylogenomic relationships of the most diverse African palm genus Raphia (Calamoideae, Arecaceae)
Helmstetter, A. J.; Bethune, K.; Lautenschlaeger, T.; Bacon, C. D.; Stauffer, F.; Antonelli, A.; Sonke, B.; Couvreur, T. L. P.
10.1101/2020.03.09.984351 — plant biology — Posted on 2020-03-11
2858 Unlocking the genomic taxonomy of the Prochloroccus collective
Tschoeke, D. A.; Vidal, L. M.; Campeao, M.; Salazar, V. W.; Swings, J.; Thompson, F. L.; Thompson, C. C.
10.1101/2020.03.09.980698 — microbiology — Posted on 2020-03-11
2860 Histone modifications during the life cycle of the brown alga Ectocarpus
Bourdareau, S.; Tirichine, L.; Lombard, B.; Damarys, L.; Scornet, D.; Coelho, S. M.; Cock, J. M.
10.1101/2020.03.09.980763 — genomics — Posted on 2020-03-11
2862 Insects and recent climate change
Halsch, C. A.; Shapiro, A. M.; Fordyce, J. A.; Nice, C. C.; Thorne, J. H.; Waetjen, D. P.; Forister, M. L.
10.1101/2020.03.09.984328 — ecology — Posted on 2020-03-11
2863 Assessment of Potential Health and Genetic Impacts in Releasing Confiscated Paroaria coronata and Saltator similis
Cruz, C. E. F. d.; Funkler, G. R.; Zani, A. L. S.; Wagner, P. G. C.; Segura, L. N.; Andretta, I.; Fagundes, N. J. R.
10.1101/2020.03.10.985473 — zoology — Posted on 2020-03-10
2866 Effects of environmental variables on the distribution of juvenile cubomedusae Carybdea marsupialis in the coastal Western Mediterranean
Bordehore, C.; Fonfria, E. S.; Alonso, C.; Rubio-Tortosa, B.; Acevedo, M. J.; Canepa, A.; Falco, S.; Rodilla, M.; Fuentes, V.
10.1101/2020.03.10.985515 — ecology — Posted on 2020-03-10
2870 Disease Risk Analysis in sea turtles: A baseline study to inform conservation efforts
Mashkour, N.; Jones, K.; Hipolito, H. V.; Kophamel, S.; Ahasan, S.; Walker, G.; Jakob-Hoff, R.; Whittaker, M.; Hamann, M.; Bell, I.; Elliman, J.; Owens, L.; Saladin, C.; Crespo-Picazo, J. L.; Gardner, B.; Loganathan, A. L.; Bowater, R.; Young, E.; Barnes, A.; Robinson, D.; Baverstock, W.; Blyde, D.; March, D.; Eghbali, M.; Mohammadi, M.; Freggi, D.; Giliam, J.; Hale, M.; Nicolle, N.; Spiby, K.; Wrobel, D.; Parga, M.; Mobaraki, A.; Rajakaruna, R.; Hyland, K. P.; Read, M.; Ariel, E.
10.1101/2020.03.10.985432 — ecology — Posted on 2020-03-10
2875 Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses
Klingmüller, U.; Robichon, K.; Maiwald, T.; Schilling, M.; Schneider, A.; Willemsen, J.; Salopiata, F.; Teusel, M.; Kreutz, C.; Ehlting, C.; Huang, J.; Chakraborty, S.; Huang, X.; Damm, G.; Seehofer, D.; Lang, P. A.; Bode, J. G.; Binder, M.; Bartenschlager, R.; Timmer, J.
10.1101/2020.03.10.985390 — systems biology — Posted on 2020-03-10
2876 Aerodynamic Characteristics and RNA Concentration of SARS-CoV-2 Aerosol in Wuhan Hospitals during COVID-19 Outbreak
Liu, Y.; Ning, Z.; Chen, Y.; Guo, M.; Liu, Y.; Gali, N. K.; Sun, L.; Duan, Y.; Cai, J.; Westerdahl, D.; Liu, X.; Ho, K.-f.; Kan, H.; Fu, Q.; Lan, K.
10.1101/2020.03.08.982637 — microbiology — Posted on 2020-03-10
2878 Control of Mycobacterium tuberculosis Infection in Lungs is Associated with Recruitment of Antigen-Specific Th1 and Th17 cells Co-expressing CXCR3 and CCR6.
Shanmugasundaram, U.; Bucsan, A. N.; Ganatra, S. R.; Ibegbu, C.; Quezada, M.; Blair, R. V.; Alvarez, X.; Velu, V.; Kaushal, D.; Rengarajan, J.
10.1101/2020.03.09.981019 — immunology — Posted on 2020-03-10
2881 Dissecting cell type-specific metabolism in pancreatic ductal adenocarcinoma
Lau, A. N.; Li, Z.; Danai, L. V.; Westermark, A. M.; Darnell, A. M.; Ferreira, R.; Gocheva, V.; Sivanand, S.; Lien, E. C.; Sapp, K. M.; Mayers, J. R.; Biffi, G.; Chin, C. R.; Davidson, S. M.; Tuveson, D. A.; Jacks, T.; Matheson, N. J.; Yilmaz, O. H.; Vander Heiden, M.
10.1101/2020.03.09.984237 — cancer biology — Posted on 2020-03-10
2882 Periodic propagating activation waves coordinate Rho GTPase network dynamics at the leading and trailing edges during cell migration
Bolado-Carrancio, A.; Rukhlenko, O. S.; Nikonova, E.; Tsyganov, M. A.; Wheeler, A.; Munoz, A. G.; Kolch, W.; von Kriegsheim, A.; Kholodenko, B. N.
10.1101/2020.03.09.984054 — systems biology — Posted on 2020-03-10
2885 Communication through coherence by means of cross-frequency coupling
Gonzalez, J.; Mondino, A.; Cavelli, M.; Rubido, N.; Tort, A. B.; Torterolo, P.
10.1101/2020.03.09.984203 — neuroscience — Posted on 2020-03-10
2888 Detailed point cloud data on stem size and shape of Scots pine trees
Saarinen, N.; Kankare, V.; Yrttimaa, T.; Viljanen, N.; Honkavaara, E.; Holopainen, M.; Hyyppa, J.; Huuskonen, S.; Hynynen, J.; Vastaranta, M.
10.1101/2020.03.09.983973 — ecology — Posted on 2020-03-10
2891 Studying the dynamics of the gut microbiota using metabolically stable isotopic labeling and metaproteomics.
Smyth, P.; Zhang, X.; Ning, Z.; Mayne, J.; Moore, J. I.; Walker, K.; Lavallée-Adam, M.; Figeys, D.
10.1101/2020.03.09.982884 — microbiology — Posted on 2020-03-10
2892 Effect of Erufosine on Membrane Lipid Order in Breast Cancer Cell Models
Tzoneva, R.; Stoyanova, T.; Petrich, A.; Popova, D.; Momchilova, A.; Chiantia, S.
10.1101/2020.03.09.983874 — biophysics — Posted on 2020-03-10
2897 BonVision - an open-source software to create and control visual environments
Lopes, G.; Farrell, K.; Horrocks, E. A. B.; Lee, C.-Y.; Morimoto, M. M.; Muzzu, T.; Papanikolaou, A.; Rodrigues, F. R.; Wheatcroft, T.; Zucca, S.; Solomon, S. G.; Saleem, A. B.
10.1101/2020.03.09.983775 — neuroscience — Posted on 2020-03-10
2899 Dopaminergic Co-transmission with Sonic Hedgehog Inhibits Expression of Abnormal Involuntary Movements
Malave, L.; Zuelke, D. R.; Starikov, L.; Rebholz, H.; Friedman, E.; Quin, C.; Li, Q.; Bezard, E.; Kottmann, A. H.
10.1101/2020.03.09.983759 — neuroscience — Posted on 2020-03-10
2900 Mitochondria-mitochondria interaction networks show altered topological patterns in Parkinson's disease
Zanin, M.; Santos, B. F. R.; Antony, P. M. A.; Berenguer-Escuder, C.; Larsen, S. B.; Hanss, Z.; Barbuti, P.; Baumuratov, A. S.; Grossmann, D.; Capelle, C.; Weber, J.; Balling, R.; Ollert, M.; Krueger, R.; Diederich, N. J.; He, F. Q.
10.1101/2020.03.09.984195 — neuroscience — Posted on 2020-03-10
2901 Oscillatory and aperiodic neural activity jointly predict grammar learning
Cross, Z. R.; Corcoran, A. W.; Schlesewsky, M.; Kohler, M. J.; Bornkessel-Schlesewsky, I.
10.1101/2020.03.10.984971 — neuroscience — Posted on 2020-03-10
2904 Combined membrane potential imaging and connectome of behavioral circuits in an annelid worm
Ashaber, M.; Tomina, Y.; Kassraian-Fard, P.; Bushong, E. A.; Kristan, W. B.; Ellisman, M. H.; Wagenaar, D. A.
10.1101/2020.03.09.984013 — neuroscience — Posted on 2020-03-10
2907 Closed-loop stimulation of the medial septum terminates epileptic seizures
Takeuchi, Y.; Harangozo, M.; Pedraza, L.; Földi, T.; Gabor, K.; Berenyi, A.
10.1101/2020.03.09.982827 — neuroscience — Posted on 2020-03-10
2908 High-Dimensional mass cytometry analysis reveals systemic immune perturbations in paediatric cancer influenced by age
Syrimi, E.; Irish, J.; Khan, N.; Willcox, B.; Willcox, C.; Murray, P.; Haigh, T.; Masand, N.; Zuo, J.; Barone, S.; Kearns, P.; Taylor, G. S.
10.1101/2020.03.09.983288 — immunology — Posted on 2020-03-10
2910 Rapamycin-dependent delocalization as a novel tool to reveal protein-protein interactions in plants
Winkler, J.; Mylle, E.; De Meyer, A.; Pavie, B.; Merchie, J.; Grones, P.; Van Damme, D.
10.1101/2020.03.09.983270 — cell biology — Posted on 2020-03-10
2911 Evolutionary variation in MADS-box dimerization affects floral development and protein degradation dynamics
Abraham-Juarez, M. J.; Schrager-Lavelle, A.; Man, J.; Whipple, C. J.; Handakumbura, P.; Babbitt, C. C.; Bartlett, M.
10.1101/2020.03.09.984260 — plant biology — Posted on 2020-03-10
2914 A TgfβRI/Snai1-dependent developmental module at the core of vertebrate axial elongation
Dias, A.; Lozovska, A.; Wymeersch, F. J.; Novoa, A.; Binagui-Casas, A.; Sobral, D.; Martins, G. G.; Wilson, V.; Mallo, M.
10.1101/2020.03.09.983809 — developmental biology — Posted on 2020-03-10
2916 KCNQ gene family members act as both tumor suppressors and oncogenes in gastrointestinal cancers
Shorthouse, D.; Rahrmann, E.; Kosmidou, C.; Greenwood, B.; Hall, M. W. J.; Devonshire, G.; Gilbertson, R.; Fitzgerald, R.; Hall, B. A.
10.1101/2020.03.10.984039 — cancer biology — Posted on 2020-03-10
2917 Structural Basis for Ca2+-Dependent Activation of a Plant Metacaspase
Zhu, P.; Yu, X.-H.; Wang, C.; Zhang, Q.; Liu, W.; McSweeney, S.; Shanklin, J.; Lam, E.; Liu, Q.
10.1101/2020.03.09.983940 — biochemistry — Posted on 2020-03-10
2918 Sex Differences in Risk-based Decision Making
Islas-Preciado, D.; Wainwright, S.; Sniegocki, J.; Lieblich, S.; Yagi, S.; Floresco, S. B.; Galea, L.
10.1101/2020.03.09.981563 — neuroscience — Posted on 2020-03-10
2921 SPIN reveals genome-wide landscape of nuclear compartmentalization
Wang, Y.; Zhang, Y.; Zhang, R.; van Schaik, T.; Zhang, L.; Sasaki, T.; Peric-Hupkes, D.; Chen, Y.; Gilbert, D. M.; van Steensel, B.; Belmont, A. S.; Ma, J.
10.1101/2020.03.09.982967 — bioinformatics — Posted on 2020-03-10
2922 Spontaneous Cell Fusions as a Mechanism of Parasexual Recombination in Tumor Cell Populations
Myroshnychenko, D.; Baratchart, E.; Ferrall-Fairbanks, M.; Vander Velde, R.; Laurie, M. A.; Bui, M.; Altrock, P. M.; Basanta, D.; Marusyk, A.
10.1101/2020.03.09.984419 — cancer biology — Posted on 2020-03-10
2923 A role for keratins in supporting mitochondrial organization and function in skin keratinocytes
Steen, K.; Chen, D.; Wang, F.; Chen, S.; Kumar, S.; Lombard, D. B.; Weigert, R.; Zieman, A. G.; Parent, C. A.; Coulombe, P. A.
10.1101/822403 — cell biology — Posted on 2020-03-10
2925 Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei
Alghamdi, A.; Munday, J. C.; Campagnaro, G. D.; Gurvic, D.; Svensson, F.; Okpara, C. E.; Kumar, A.; Martin Abril, M. E.; Mili?, P.; Watson, L.; Paape, D.; Settimo, L.; Dimitriou, A.; Wielinska, J.; Smart, G.; Anderson, L. F.; Woodley, C. M.; Kelly, S. P. Y.; Ibrahim, H. M.; Hulpia, F.; Al-Salabi, M. I.; Eze, A. A.; Teka, I. A.; Gudin, S.; Dardonville, C.; Tidwell, R. R.; Carrington, M.; O'Neill, P.; Boykin, D. W.; Zachariae, U.; De Koning, H. P.
10.1101/2020.03.08.982751 — biochemistry — Posted on 2020-03-10
2926 Timing of organ initiation is crucial for robust organ size
Zhu, M.; Chen, W.; Mirabet, V.; Hong, L.; Bovio, S.; Strauss, S.; Schwarz, E. M.; Tsugawa, S.; Wang, Z.; Smith, R. S.; Li, C.-B.; Hamant, O.; Boudaoud, A.; Roeder, A. H. K.
10.1101/2020.03.08.982629 — plant biology — Posted on 2020-03-10
2929 A Systematic Protein Turnover Map for Decoding Protein Degradation
Christiano, R.; Kabatnik, S.; Mejhert, N.; Farese, R. V.; Walther, T. C.
10.1101/2020.03.09.983734 — systems biology — Posted on 2020-03-09
2930 Unraveling Oxidative Stress Resistance: Molecular Properties Govern Proteome Vulnerability
Chang, R. L.; Stanley, J. A.; Robinson, M. C.; Sher, J. W.; Li, Z.; Chan, Y. A.; Omdahl, A. R.; Wattiez, R.; Godzik, A.; Matallana-Surget, S.
10.1101/2020.03.09.983213 — systems biology — Posted on 2020-03-09
2933 Reshaping of the Arabidopsis thaliana proteome landscape and co-regulation of proteins in development and immunity
Bassal, M.; Majovsky, P.; Thieme, D.; Herr, T.; Abukhalaf, M.; Ayash, M.; Al Shweiki, M. R.; Proksch, C.; Hmedat, A.; Ziegler, J.; Neumann, S.; Hoehenwarter, W.
10.1101/2020.03.09.978627 — plant biology — Posted on 2020-03-09
2940 The Drosophila Amyloid Precursor Protein homologue mediates neuronal survival and neuro-glial interactions
Kessissoglou, I.; Langui, D.; Hasan, A.; Maral, M.; Dutta, S.; Hiesinger, P. R.; Hassan, B. A.
10.1101/2020.03.09.983353 — neuroscience — Posted on 2020-03-09
2941 An Xist-dependent protein assembly mediates Xist localization and gene silencing
Plath, K.; Black, D. L.; Pandya-Jones, A.; Markaki, Y.; Serizay, J.; Chitiashvili, T.; Mancia, W.; Damianov, A.; Chronis, K.; Papp, B.; Chen, C.-K.; McKee, R.; Wang, X.-J.; Chau, A.; Leonhardt, H.; Zheng, S.; Guttman, M.
10.1101/2020.03.09.979369 — molecular biology — Posted on 2020-03-09
2942 Naringenin as an antibacterial reagent controlling of biofilm formation and fatty acid metabolism in MRSA
Song, H.-S.; Bhatia, S. K.; Gurav, R.; Choi, T.-R.; Kim, H. J.; Park, Y.-L.; Han, Y.-H.; Park, J. Y.; Lee, S. m.; Park, S. L.; Lee, H. S.; Kim, W.; Kim, Y.-G.; Yang, Y.-H.
10.1101/2020.03.08.983049 — microbiology — Posted on 2020-03-09
2946 Transcriptomic characterization of tuberculous sputum reveals a host Warburg effect and microbial cholesterol catabolism
Lai, R. P.; Cortes, T.; Marais, S.; Rockwood, N.; Burke, M. L.; Garza-Garcia, A.; Horswell, S.; O'Garra, A.; Young, D. B.; Wilkinson, R. J.
10.1101/2020.03.09.983163 — microbiology — Posted on 2020-03-09
2947 Antibacterial efficacy of Jackfruit rag extract against clinically important pathogens and validation of its antimicrobial activity in Shigella dysenteriae infected Drosophila melanogaster infection model
V, D. N.; Mathew, S. E.; Baranwal, G.; Shivaram, S. B.; Katiyar, N.; Pramanik, N.; Jhunjhunwala, S.; B, S. H.; Nagegowda, D. A.; Kumar, R.; Shasany, A. K.; Biswas, R.; Shankarappa, S. A.
10.1101/2020.03.09.983015 — microbiology — Posted on 2020-03-09
2948 Reprogramming the endogenous type III-A CRISPR-Cas system for genome editing, RNA interference and CRISPRi screening in Mycobacterium tuberculosis
Rahman, K.; Jamal, M.; Chen, X.; Zhou, W.; Yang, B.; Zou, Y.; Xu, W.; Lei, Y.; Wu, C.; Cao, X.; Tyagi, R.; Naeem, M. A.; Lin, D.; Habib, Z.; Peng, N.; Fu, Z. F.; Cao, G.
10.1101/2020.03.09.983494 — microbiology — Posted on 2020-03-09
2952 Schistosoma Japonicum infection in Treg-specific USP21 knock-out mice
Zhang, Y.; Xu, G.; Zhang, B.; Zhang, S.; Li, Y.; Huang, Q.; Chen, S.; Zeng, F.; Li, B.; Qin, Z.; Zhang, Z.
10.1101/2020.03.09.983502 — immunology — Posted on 2020-03-09
2953 Systemic mutational rescue in Escherichia coli elicited by a valency dependent, high affinity protein DNA interaction
Hurd, P.; Al-Swailem, A. M.; Bin-Dukhyil, A.; Sheikh, Q. I.; Al-Ghanim, A.; Alfageih, L.; Matin, M.; Lu, Y. T.; Abdalgelel, A.; Florence, J.; Al-Shemirti, M.; Al Harbi, S.; Brown, P. E.; Hornby, D. P.
10.1101/2020.03.09.983320 — genomics — Posted on 2020-03-09
2958 The evolutionary history of Neandertal and Denisovan Y chromosomes
Petr, M.; Hajdinjak, M.; Fu, Q.; Essel, E.; Rougier, H.; Crevecoeur, I.; Semal, P.; Golovanova, L. V.; Doronichev, V. B.; Lalueza-Fox, C.; de la Rasilla, M.; Rosas, A.; Shunkov, M. V.; Kozlikin, M. B.; Derevianko, A. P.; Vernot, B.; Meyer, M.; Kelso, J.
10.1101/2020.03.09.983445 — evolutionary biology — Posted on 2020-03-09
2960 Episodic evolution of coadapted sets of amino acid sites in mitochondrial proteins
Neverov, A.; Fedonin, G.; Cheremukhin, E. A.; Klink, G.; Popova, A.; Bazykin, G.
10.1101/2020.03.09.983361 — evolutionary biology — Posted on 2020-03-09
2963 What happens to oak growth and survival when there is both competition and browsing?
Jensen, A. M.; Petersson, L. K.; Felton, A.; Löf, M.; Persson, M. A. M.
10.1101/2020.03.09.983437 — ecology — Posted on 2020-03-09
2966 Self-labeling of proteins with chemical fluorescent dyes in BY-2 cells and Arabidopsis seedlings
Frommer, W. B.; Iwatate, R.; Nakamura, M.; Yoshinari, A.; Yagi, N.; Yamaguschi, S.; Taki, M.; Komatsu, T.; Kamiya, M.; Ogasawara, H.; Grzybowski, M.
10.1101/2020.03.09.983924 — cell biology — Posted on 2020-03-09
2968 EOMES and IL-10 regulate anti-tumor activity of PD-1+ CD4+ T-cells in B-cell Non-Hodgkin lymphoma
Roessner, P. M.; LLaó Cid, L.; Lupar, E.; Roider, T.; Bordas, M.; Schifflers, C.; Gaupel, A.-C.; Kilpert, F.; Krötschel, M.; Arnold, S. J.; Sellner, L.; Stilgenbauer, S.; Dietrich, S.; Lichter, P.; Izcue, A.; Seiffert, M.
10.1101/2020.03.09.983098 — cancer biology — Posted on 2020-03-09
2969 SCLC_CellMiner: Integrated Genomics and Therapeutics Predictors of Small Cell Lung Cancer Cell Lines based on their genomic signatures
Tlemsani, C.; Pongor, L.; Girard, L.; Roper, N.; Elloumi, F.; Varma, S.; Luna, A.; Rajapakse, V. N.; Sebastian, R.; Kohn, K. W.; Krushkal, J.; Aladjem, M.; Teicher, B.; Meltzer, P. S.; Reinhold, W. C.; Minna, J. D.; Thomas, A.; Pommier, Y.
10.1101/2020.03.09.980623 — cancer biology — Posted on 2020-03-09
2970 Dual Energy X-ray Absorptiometry (DEXA) as a Longitudinal Outcome Measure of Cancer-Related Muscle Wasting in Mice
Cole, C. L.; Robinson, D.; Ye, J.; Mills, B.; Gerber, S. A.; Beck, C. A.; Schwarz, E. M.; Linehan, D.
10.1101/2020.03.09.983403 — cancer biology — Posted on 2020-03-09
2975 Identification of Conserved Evolutionary Trajectories in Tumors
Hodzic, E.; Shrestha, R.; Malikic, S.; Collins, C. C.; Litchfield, K.; Turajlic, S.; Sahinalp, C.
10.1101/2020.03.09.967257 — bioinformatics — Posted on 2020-03-09
2977 In-vivo Transcriptomic Profiling of Systemic Aging using Cell Encapsulation
Mashinchian, O.; Hong, X.; Migliavacca, E.; Boss, C.; De Franceschi, F.; Michaud, J.; Le Moal, E.; Collerette-Tremblay, J.; Isern, J.; Metairon, S.; Raymond, F.; Descombes, P.; Bouche, N.; Munoz-Canoves, P.; Feige, J. N.; Bentzinger, C. F.
10.1101/2020.03.09.979054 — bioengineering — Posted on 2020-03-09
2988 Fission yeast Pak1 phosphorylates anillin-like Mid1 for spatial control of cytokinesis
Magliozzi, J. O.; Sears, J.; Cressey, L.; Brady, M.; Opalko, H. E.; Kettenbach, A. N.; Moseley, J. B.
10.1101/722900 — cell biology — Posted on 2020-03-10
2991 RIG-I and PKR, but not stress granules, mediate the pro-inflammatory response to Yellow fever virus
Beauclair, G.; Streicher, F.; Bruni, D.; Gracias, S.; Bourgeau, S.; Sinigaglia, L.; Fujita, T.; Meurs, E. F.; Tangy, F.; jouvenet, n.
10.1101/2020.02.05.935486 — microbiology — Posted on 2020-03-10
2993 Drosophila models of pathogenic copy-number variant genes show global and non-neuronal defects during development
Yusuff, T.; Jensen, M.; Yennawar, S.; Pizzo, L.; Karthikeyan, S.; Gould, D. J.; Sarker, A.; Gedvilaite, E.; Matsui, Y.; Iyer, J.; Lai, Z.-C.; Girirajan, S.
10.1101/855338 — genomics — Posted on 2020-03-10
2994 Fingerprints of high-dimensional coexistence in complex ecosystems
Barbier, M.; de Mazancourt, C.; Loreau, M.; Bunin, G.
10.1101/652230 — ecology — Posted on 2020-03-10
2995 Her9/HES4 is required for retinal photoreceptor development, maintenance, and survival
Coomer, C. E.; Wilson, S. G.; Titialii-Torres, K. F.; Bills, J. D.; Krueger, L. A.; Petersen, R. A.; Turnbaugh, E. M.; Janesch, E. L.; Morris, A. C.
10.1101/833301 — developmental biology — Posted on 2020-03-10
2997 Cancer Stem Cell Enrichment and Metabolic Substrate Adaptability are Driven by Hydrogen Sulfide Suppression in Glioblastoma
Silver, D. J.; Roversi, G. A.; Bithi, N.; Neumann, C. K. A.; Troike, K. M.; Ahuja, G. K.; Reizes, O.; Brown, J. M.; Hine, C.; Lathia, J. D.
10.1101/2020.03.08.982116 — cancer biology — Posted on 2020-03-10
2999 A generalized machine-learning aided method for targeted identification of industrial enzymes from metagenome: a xylanase temperature dependence case study
Foroozandeh Shahraki, M.; Farhadyar, K.; Kavousi, K.; Azarabad, M. H.; Boroomand, A.; Ariaeenejad, S.; Hosseini Salekdeh, G.
10.1101/826040 — bioinformatics — Posted on 2020-03-10
3000 Structure of Mpro from COVID-19 virus and discovery of its inhibitors
Jin, Z.; Du, X.; Xu, Y.; Deng, Y.; Liu, M.; Zhao, Y.; Zhang, B.; Li, X.; Zhang, L.; Peng, C.; Duan, Y.; Yu, J.; Wang, L.; Yang, K.; Liu, F.; Jiang, R.; Yang, X.; You, T.; Liu, X.; Yang, X.; Bai, F.; Liu, H.; Liu, X.; Guddat, L. W.; Xu, W.; Xiao, G.; Qin, C.; Shi, Z.; Jiang, H.; Rao, Z.; Yang, H.
10.1101/2020.02.26.964882 — biochemistry — Posted on 2020-03-10
3001 Lipid Sponge Droplets as Programmable Synthetic Organelles
Bhattacharya, A.; Niederholtmeyer, H.; Podolsky, K. A.; Bhattacharya, R.; Song, J.-J.; Brea, R. J.; Tsai, C.-H.; Sinha, S. K.; Devaraj, N. K.
10.1101/2020.01.20.913350 — synthetic biology — Posted on 2020-03-10
3005 Biological data questions the support of the self inhibition required for pattern generation in the half center model.
Kohler, M.; Stratmann, P.; Roehrbein, F.; Knoll, A.; Alin Albu-Schaeffer, A.; Joerntell, H.
10.1101/851154 — neuroscience — Posted on 2020-03-10
3006 Prenatal exposure to perfluoroalkyl substances modulates neonatal serum phospholipids, increasing risk of type 1 diabetes
McGlinchey, A.; Sinioja, T.; Lamichhane, S.; Sen, P.; Bodin, J.; Siljander, H.; Dickens, A. M.; Geng, D.; Carlsson, C.; Duberg, D.; Ilonen, J.; Virtanen, S. M.; Dirven, H.; Bentsen, H. F.; Zimmer, K.; Nygaard, U. C.; Oresic, M.; Knip, M.; Hyotylainen, T.
10.1101/588350 — molecular biology — Posted on 2020-03-10
3008 Data-driven modelling of mutational hotspots and in-silico predictors in hypertrophic cardiomyopathy
Waring, A.; Harper, A.; Salatino, S.; Kramer, C.; Neubauer, S.; HCMR Investigators, ; Thomson, K.; Watkins, H.; Farrall, M.
10.1101/826164 — genetics — Posted on 2020-03-10
3009 Alanine tRNAs translate environment into behavior in Caenorhabditis elegans
Fernandes De Abreu, D. A.; Salinas-Giege, T.; Marechal-Drouard, L.; Remy, J.-J.
10.1101/289629 — evolutionary biology — Posted on 2020-03-10
3010 Beyond a single patch: local and regional processes explain diversity patterns in a seagrass epifaunal metacommunity
Stark, K. A.; Thompson, P. L.; Yakimishyn, J.; Lee, L.; Adamczyk, E. M.; Hessing-Lewis, M.; O'Connor, M. I.
10.1101/482406 — ecology — Posted on 2020-03-10
3011 Id proteins promote a cancer stem cell phenotype in triple negative breast cancer via negative regulation of Robo1
Teo, W. S.; Holliday, H.; Karthikeyan, N.; Cazet, A. S.; Roden, D. L.; Harvey, K.; Konrad, C. V.; Murali, R.; Varghese, B. A.; T., A. P.; Chan, C.-L.; McFarland, A.; Junankar, S.; Ye, S.; Yang, J.; Nikolic, I.; Shah, J. S.; Baker, L. A.; Millar, E. K. A.; Naylor, M. J.; Ormandy, C. J.; Lakhani, S. R.; Kaplan, W.; Mellick, A. S.; O'Toole, S. A.; Swarbrick, A.; Nair, R.
10.1101/497313 — cancer biology — Posted on 2020-03-10
3014 Divergent strategies for learning in males and females
Chen, C. S.; Ebitz, R. B.; Bindas, S.; Redish, A. D.; Hayden, B.; Grissom, N. M.
10.1101/852830 — animal behavior and cognition — Posted on 2020-03-10
3015 High-density lipoprotein characteristics and coronary heart disease: a Mendelian randomization study
Prats-Uribe, A.; Sayols-Baixeras, S.; Fernandez-Sanles, A.; Subirana, I.; Carreras-Torres, R.; Vilahur, G.; Civeira, F.; Marrugat, J.; Fito, M.; Hernaez, A.; Elosua, R.
10.1101/673939 — epidemiology — Posted on 2020-03-10
3016 Global cropland connectivity: A risk factor for invasion and saturation by emerging pathogens and pests
Xing, Y.; Hernandez Nopsa, J.; Andersen, K. F.; Andrade-Piedra, J.; Beed, F.; Blomme, G.; Carvajal Yepes, M.; Coyne, D.; Cuellar, W.; Forbes, G.; Kreuze, J.; Kroschel, J.; Kumar, L.; Legg, J.; Parker, M.; Schulte-Geldermann, E.; Sharma, K.; Garrett, K.
10.1101/106542 — ecology — Posted on 2020-03-10
3017 Estimating the rate of plasmid transfer in liquid mating cultures
Huisman, J. S.; Benz, F.; Duxbury, S. J. N.; de Visser, J. A. G. M.; Hall, A. R.; Fischer, E. A. J.; Bonhoeffer, S.
10.1101/2020.03.09.980862 — microbiology — Posted on 2020-03-09
3021 Evidence for a biological source of widespread, reproducible nighttime oxygen spikes in tropical reef ecosystems has implications for coral health
Calhoun, S. K.; Haas, A. F.; Takeshita, Y.; Johnson, M. D.; Fox, M. D.; Kelly, E. L. A.; Mueller, B.; Vermeij, M. J. A.; Kelly, L. W.; Nelson, C. E.; Price, N. N.; Roach, T. N. F.; Rohwer, F.; Smith, J. E.
10.1101/2020.03.08.982645 — ecology — Posted on 2020-03-09
3022 Chromatin-Bound PARP1 Correlates with Upregulation of Inflammatory Genes in Response to Long-Term Treatment with Veliparib
Alvarado-Cruz, I.; Mahmoud, M.; Khan, M.; Zhao, S.; Oeck, S.; Meas, R.; Clairmont, K.; Quintana, V.; Zhu, Y.; Porciuncula, A.; Wyatt, H.; Ma, S.; Shyr, Y.; Kong, Y.; LoRusso, P. M.; Laverty, D.; Nagel, Z. D.; Schalper, K. A.; Krauthammer, M.; Sweasy, J. B.
10.1101/2020.03.08.982785 — cancer biology — Posted on 2020-03-09
3030 Single-cell transcriptomics of allo-reactive CD4+ T cells over time reveals divergent fates during gut GVHD
Engel, J. A.; Lee, H. J.; Williams, C. G.; Kuns, R.; Olver, S.; Lansink, L. I. M.; Soon, M. S. F.; Andersen, S. B.; Powell, J. E.; Svensson, V.; Teichmann, S. A.; Hill, G. R.; Varelias, A.; Koyama, M.; Haque, A.
10.1101/2020.03.08.978239 — immunology — Posted on 2020-03-09
3035 Inhibition of IL34 unveils tissue-selectivity and is sufficient to reduce microglial proliferation in chronic neurodegeneration
Obst, J.; Simon, E.; Martin-Estebane, M.; Pipi, E.; Barkwill, L.; Gonzalez-Rivera, Y.; Buchanan, F.; Prescott, A. R.; Faust, D.; Fox, S.; Brownlees, J.; Taylor, D.; Perry, V. H.; Nuthall, H.; Atkinson, P. J.; Karran, E.; Routledge, C.; Gomez-Nicola, D.
10.1101/2020.03.09.976118 — neuroscience — Posted on 2020-03-09
3038 Rainforest-to-pasture conversion stimulates soil methanogenesis across the Brazilian Amazon
Kroeger, M. E.; Meredith, L. K.; Meyer, K. M.; Webster, K. D.; Barbosa de Camargo, P.; Fonseca de Souza, L.; Tsai, S. M.; van Haren, J.; Saleska, S.; Bohannan, B. J. M.; Rodrigues, J. L. M.; Nüsslein, K.
10.1101/2020.03.08.982587 — microbiology — Posted on 2020-03-09
3042 X-chromosome dosage compensation dynamics in human early embryos
Fan, G.; Zeng, Q.; Feng, Y.; Hu, Y.; An, Q.; Li, T.; Qin, L.-J.; Xue, Z.; Huang, K.; Liu, J.-y.
10.1101/2020.03.08.982694 — developmental biology — Posted on 2020-03-09
3044 A lipid atlas of human carotid atherosclerosis
Moerman, A. M.; Visscher, M.; Slijkhuis, N.; Van Gaalen, K.; Heijs, B.; Klein, T.; Burgers, P. C.; De Rijke, Y. B.; Van Beusekom, H. M.; Luider, T.; Verhagen, H. J.; Van der Steen, A. F.; Gijsen, F. J.; Van der Heiden, K.; Van Soest, G.
10.1101/2020.03.09.976043 — biochemistry — Posted on 2020-03-09
3046 Cancer Stem Cell Enrichment and Metabolic Substrate Adaptability are Driven by Hydrogen Sulfide Suppression in Glioblastoma
Silver, D. J.; Roversi, G. A.; Bithi, N.; Neumann, C. K. A.; Troike, K. M.; Reizes, O.; Brown, J. M.; Hine, C.; Lathia, J. D.
10.1101/2020.03.08.982116 — cancer biology — Posted on 2020-03-09
3047 Light-responsive monobodies for dynamic control of customizable protein binding
Carrasco-Lopez, C.; Zhao, E.; Gil, A. A.; Alam, N.; Toettcher, J. E.; Avalos, J. L.
10.1101/2020.03.08.831909 — biochemistry — Posted on 2020-03-09
3048 Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in Rheumatoid Arthritis.
Wang, Y.; Khan, A.; Antonopoulos, A.; Bouche, L.; Buckley, C. D.; Filer, A.; Raza, K.; Ping-Li, K.; Tolusso, B.; Gremese, E.; Kurowska-Stolarska, M.; Alivernini, S.; Dell, A.; Haslam, S. M.; Pineda, M. A.
10.1101/2020.03.08.970046 — immunology — Posted on 2020-03-09
3050 Synchronous Caregiving from Birth to Adulthood Tunes Humans' Social Brain
Ulmer Yaniv, A.; Salomon, R.; Waidergoren, S.; Shimon-Raz, O.; Djalovski, A.; Feldman, R.
10.1101/2020.03.09.974659 — neuroscience — Posted on 2020-03-09
3052 Conjugates of neuroprotective chaperone L-PGDS provide MRI contrast for detection of amyloid β-rich regions in live Alzheimer's Disease mouse model brain
Sharma, B.; Grandjean, J.; Phillips, M.; Kumar, A.; Mandino, F.; Yeow, L.-Y.; Nandwana, V.; Dravid, V. P.; Bengang, X.; Lim, S.; Pervushin, K.
10.1101/2020.03.08.982363 — biochemistry — Posted on 2020-03-09
3054 Assembly Mechanism of Mucin and von Willebrand Factor Polymers
Javitt, G.; Khmelnitsky, L.; Albert, L.; Elad, N.; Ilani, T.; Diskin, R.; Fass, D.
10.1101/2020.03.08.982447 — molecular biology — Posted on 2020-03-09
3055 African swine fever virus-like integrated elements in a soft tick genome - an ancient virus vector arms race?
Forth, J. H.; Forth, L. F.; Lycett, S. J.; Bell-Sakyi, L.; Keil, G. M.; Blome, S.; Calvignac-Spencer, S.; Wissgott, A.; Krause, J.; Hoeper, D.; Kampen, H.; Beer, M.
10.1101/2020.03.08.978106 — microbiology — Posted on 2020-03-09
3057 Protein induced membrane phase transition facilitates leishmania infection
Sannigrahi, A.; Jawed, J. J.; Majumdar, S.; Roy, S.; Karmakar, S.; Chattopadhyay, K.
10.1101/2020.03.08.982454 — biophysics — Posted on 2020-03-09
3059 Real-time Ratiometric Imaging of Micelles Assembly State in a Microfluidic Cancer-on-a-chip
Feiner-Gracia, N.; Glinkowska Mares, A.; Buzhor, M.; Rodriguez-Trujillo, R.; Samitier, J.; Amir, R.; Pujals, S.; Albertazzi, L.
10.1101/2020.03.08.978783 — bioengineering — Posted on 2020-03-09
3060 Improving the chromosome-level genome assembly of the Siamese fighting fish (Betta splendens) in a university Master's course.
Prost, S.; Petersen, M.; Grethlein, M.; Hahn, S. J.; Kuschik-Maczollek, N.; Olesiuk, M. E.; Reschke, J.-O.; Schmey, T. E.; Zimmer, C.; Gupta, D. K.; Schell, T.; Coimbra, R.; De Raad, J.; Lammers, F.; Winter, S.; Janke, A.
10.1101/2020.03.06.981332 — evolutionary biology — Posted on 2020-03-09
3062 Quantifying the Limits of Immunotherapies in Mice and Men
Brown, L. V.; Gaffney, E. A.; Ager, A.; Wagg, J.; Coles, M. C.
10.1101/759167 — cancer biology — Posted on 2020-03-09
3064 Altered Sensorimotor-to-Transmodal Hierarchical Organization in Schizophrenia
Dong, D.; Yao, D.; Wang, Y.; Hong, S.-J.; Genon, S.; Xin, F.; Jung, K.; He, H.; Chang, X.; Duan, M.; Bernhardt, B.; Margulies, D. S.; Sepulcre, J.; Eickhoff, S. B.; Luo, C.
10.1101/2020.03.06.980607 — neuroscience — Posted on 2020-03-09
3065 Plasmodium oocysts respond with dormancy to crowding and nutritional stress
Habtewold, T.; Sharma, A. A.; Masters, E. K. G.; Wyer, C. A. S.; Windbichler, N.; Christophides, G. K.
10.1101/2020.03.07.981951 — microbiology — Posted on 2020-03-09
3066 Differential B-cell receptor signaling requirement for adhesion of mantle cell lymphoma cells to stromal cells
Sadeghi, l.; Arvidsson, G.; Merrien, M.; Wasik, A. M.; Görgens, A.; Smith, E.; Sander, B.; Wright, A. P.
10.1101/2020.03.06.980235 — cancer biology — Posted on 2020-03-09
3068 Data-driven modelling of mutational hotspots and in-silico predictors in hypertrophic cardiomyopathy
Waring, A.; Harper, A.; Salatino, S.; Kramer, C.; Neubauer, S.; HCMR Investigators, ; Thomson, K.; Watkins, H.; Farrall, M.
10.1101/826164 — genetics — Posted on 2020-03-09
3069 Ruler elements in chromatin remodelers set nucleosome array spacing and phasing
Oberbeckmann, E.; Niebauer, V.; Watanabe, S.; Farnung, L.; Moldt, M.; Schmid, A.; Cramer, P.; Peterson, C. L.; Eustermann, S.; Hopfner, K.-P.; Korber, P.
10.1101/2020.02.28.969618 — biochemistry — Posted on 2020-03-09
3070 Application of high-resolution landmark-free morphometrics to a mouse model of Down Syndrome reveals a tightly localised cranial phenotype
Toussaint, N.; Redhead, Y.; Liu, W.; Fisher, E.; Hallgrimsson, B.; Tybulewicz, V.; Schnabel, J.; Green, J. B. A.
10.1101/711259 — genetics — Posted on 2020-03-09
3075 A novel allele of ASY3 promotes meiotic stability in autotetraploid Arabidopsis lyrata
Seear, P. J.; France, M. G.; Gregory, C. L.; Heavens, D.; Schmickl, R.; Yant, L.; Higgins, J. D.
10.1101/2019.12.25.888388 — evolutionary biology — Posted on 2020-03-09
3077 Optical flow analysis reveals that Kinesin-mediated advection impacts on the orientation of microtubules in the Drosophila oocyte
Drechsler, M.; Lang, L. F.; al-Khatib, L.; Dirks, H.; Burger, M.; Schoenlieb, C.-B.; Palacios, I. M.
10.1101/556043 — cell biology — Posted on 2020-03-09
3078 An Orthographic Prediction Error as the basis for efficient Visual Word Recognition
Gagl, B.; Sassenhagen, J.; Haan, S.; Gregorova, K.; Richlan, F.; Fiebach, C. J.
10.1101/431726 — neuroscience — Posted on 2020-03-09
3079 Geological degassing enhances microbial metabolism in the continental subsurface
Bornemann, T. L.; Adam, P. S.; Turzynski, V.; Schreiber, U.; Figueroa-Gonzalez, P. A.; Rahlff, J.; Koester, D.; Schmidt, T. C.; Schunk, R.; Krauthausen, B.; Probst, A. J.
10.1101/2020.03.07.980714 — microbiology — Posted on 2020-03-09
3080 Oxidative and non-oxidative active turnover of genomic methylcytosine in distinct pluripotent states
Spada, F.; Schiffers, S.; Kirchner, A.; Zhang, Y.; Arista, G.; Kosmatchev, O.; Korytiakova, E.; Rahimoff, R.; Ebert, C.; Carell, T.
10.1101/846584 — cell biology — Posted on 2020-03-09
3082 Removing unwanted variation between samples in Hi-C experiments
Fletez-Brant, K.; Qiu, Y.; Gorkin, D. U.; Hu, M.; Hansen, K. D.
10.1101/214361 — genomics — Posted on 2020-03-09
3083 A mathematical dissection of the adaptation of cell populations to fluctuating oxygen levels
Ardaseva, A.; Gatenby, R. A.; Anderson, A. R. A.; Byrne, H. M.; Maini, P. K.; Lorenzi, T.
10.1101/827980 — cancer biology — Posted on 2020-03-09
3084 Qtlizer: comprehensive QTL annotation of GWAS results
Munz, M.; Wohlers, I.; Simon, E.; Reinberger, T.; Busch, H.; Schaefer, A. S.; Erdmann, J.
10.1101/495903 — bioinformatics — Posted on 2020-03-09
3085 Interpretable multimodal deep learning for real-time pan-tissue pan-disease pathology search on social media
Schaumberg, A. J.; Juarez-Nicanor, W. C.; Choudhury, S. J.; Pastrian, L. G.; Pritt, B. S.; Prieto Pozuelo, M.; Sotillo Sanchez, R.; Ho, K.; Zahra, N.; Sener, B. D.; Yip, S.; Xu, B.; Annavarapu, S. R.; Morini, A.; Jones, K. A.; Rosado-Orozco, K.; Mukhopadhyay, S.; Miguel, C.; Yang, H.; Rosen, Y.; Ali, R. H.; Folaranmi, O. O.; Gardner, J. M.; Suleiman, D. E.; Rusu, C.; Stayerman, C.; Gross, J.; Sirintrapun, S. J.; Aly, M.; Fuchs, T. J.
10.1101/396663 — pathology — Posted on 2020-03-09
3087 Sfrp1 deficiency makes retinal photoreceptors prone to degeneration
Cisneros, E.; Di Marco, F.; Rueda-Carrasco, J.; LILLO, C.; Pereyra, G.; Martin-Bermejo, M. J.; Vargas, A.; Sanchez, R.; Sandonis, A.; Esteve, P.; Bovolenta, P.
10.1101/831479 — neuroscience — Posted on 2020-03-09
3088 Mechanistic macroecology: exploring the drivers of latitudinal variation in terrestrial body size in a General Ecosystem Model
Harfoot, M. B. J.; Abraham, A.; Tittensor, D. P.; Costa, G. C.; Faurby, S.; Feldman, A.; Itescu, Y.; Meiri, S.; Morales-Castilla, I.; Oliveira, B. F.; Purves, D.
10.1101/775957 — ecology — Posted on 2020-03-09
3091 Chromosome contact maps are bifractal
Pigolotti, S.; Jensen, M. H.; Zhan, Y.; Tiana, G.
10.1101/686279 — biophysics — Posted on 2020-03-09
3094 α-Synuclein-induced Kv4 channelopathy in mouse vagal motoneurons causes non-motor parkinsonian symptoms
Chiu, W.-H.; Kovacheva, L.; Musgrove, R. E.; Arien-Zakay, H.; Koprich, J. B.; Brotchie, J. M.; Yaka, R.; Ben-Zvi, D.; Hanani, M.; Roeper, J.; Goldberg, J. A.
10.1101/856070 — neuroscience — Posted on 2020-03-09
3095 Oxytocin Neurons Enable Social Transmission of Maternal Behavior
Carcea, I.; Lopez Caraballo, N.; Marlin, B.; Ooyama, R.; Riceberg, J.; Mendoza Navarro, J.; Opendak, M.; Diaz, V.; Schuster, L.; Alvarado Torres, M.; Lethin, H.; Ramos, D.; Minder, J.; Mendoza, S.; Hidema, S.; Falkner, A.; Lin, D.; Mar, A.; Wadghiri, Y.; Nishimori, K.; Kikusui, T.; Mogi, K.; Sullivan, R.; Froemke, R.
10.1101/845495 — neuroscience — Posted on 2020-03-09
3096 An Effective CTL Peptide Vaccine for Ebola Zaire Based on Survivors' CD8+ Targeting of a Particular Nucleocapsid Protein Epitope with Potential Implications for COVID-19 Vaccine Design
Herst, C. V.; Burkholz, S.; Sidney, J.; Sette, A.; Harris, P. E.; Massey, S.; Brasel, T.; Cunha-Neto, E.; Rosa, D. S.; Chao, W. C. H.; Carback, R. T.; Hodge, T.; Wang, L.; Ciotlos, S.; Lloyd, P.; Rubsamen, R. M.
10.1101/2020.02.25.963546 — immunology — Posted on 2020-03-09
3097 Discovery of novel functions of minor ZGA gene on heart and vascular regulation in Golden pompano genome provides clues for anti-cancer therapeutic strategies
LUo, H.; Zhang, Y.; Ji, C.; Zhao, Y.; Peng, J.; Chen, X.; Li, L.; Huang, Y.; Liu, Q.; He, P.; Feng, P.; Yang, C.; Wei, P.; Yu, H.; Zheng, H.; Lin, Y.; Chen, X.
10.1101/804609 — genomics — Posted on 2020-03-09
3099 Global & Temporal Patterns of Submicroscopic Plasmodium falciparum Malaria Infection
Whittaker, C.; Slater, H. C.; Bousema, T.; Drakeley, C.; Ghani, A.; Okell, L. C.
10.1101/554311 — epidemiology — Posted on 2020-03-09
3100 Conserved epigenetic regulatory logic infers genes governing cell identity
Shim, W. J.; Sinniah, E.; Xu, J.; Vitrinel, B.; Alexanian, M.; Andreoletti, G.; Shen, S.; Balderson, B.; Peng, G.; Jing, N.; Sun, Y.; Wang, Y.; Tam, P.; Smith, A.; Piper, M.; Christiaen, L.; Nguyen, Q.; Boden, M.; Palpant, N.
10.1101/635516 — cell biology — Posted on 2020-03-09
3102 Women's brain aging: effects of sex-hormone exposure, pregnancies, and genetic risk for Alzheimer's disease
de Lange, A.-M. G.; Barth, C.; Kaufmann, T.; Maximov, I.; van der Meer, D.; Agartz, I.; Westlye, L. T.
10.1101/826123 — neuroscience — Posted on 2020-03-09
3103 Promoter scanning during transcription initiation in Saccharomyces cerevisiae: Pol II in the "shooting gallery"
Qiu, C.; Jin, H.; Vvedenskaya, I.; Llenas, J. A.; Zhao, T.; Malik, I.; Visbisky, A. M.; Schwartz, S. L.; Cui, P.; Cabart, P.; Han, K. H.; Lai, W. K. M.; Metz, R. P.; Johnson, C. D.; Sze, S.-H.; Pugh, B. F.; Nickels, B. E.; Kaplan, C. D.
10.1101/810127 — molecular biology — Posted on 2020-03-09
3104 A pleiotropic chemoreceptor facilitates the coupling of pheromonal signal perception and production
Zelle, K.; Vernier, C.; Liang, X.; Halloran, S.; Millar, J.; Ben-Shahar, Y.
10.1101/124305 — genetics — Posted on 2020-03-09
3105 Robust Production of Uniform Human Cerebral Organoids from Pluripotent Stem Cells
Sivitilli, A.; Gosio, J.; Ghoshal, B.; Evstratova, A.; Trcka, D.; Ghiasighorveh, P.; Hernandez, J.; Beaulieu, M.; Wrana, J.; Attisano, L.
10.1101/2020.03.08.979013 — neuroscience — Posted on 2020-03-08
3107 Chromosight: A computer vision program for pattern detection in chromosome contact maps
Matthey-Doret, C.; Baudry, L.; Breuer, A.; Guiglielmoni, N.; Moreau, P.; Vigouroux, A.; Montagne, R.; Scolari, V.; Politis, L.; Meot, A.; Oriol, E.; Chanut, P.-H.; Campeas, A.; Jean, E.; Koszul, R.; Cournac, A.
10.1101/2020.03.08.981910 — bioinformatics — Posted on 2020-03-08
3108 Assessing trait driver theory along abiotic gradients in tropical plant communities
Lourenco, J.; Newman, E. A.; Dias Milanez, C. R.; Thomaz, L. D.; Enquist, B. J.
10.1101/2020.02.15.950139 — ecology — Posted on 2020-03-08
3111 Adaptation supports short-term memory in a visual change detection task
Hu, B.; Garrett, M. E.; Groblewski, P. A.; Ollerenshaw, D. R.; Shang, J.; Roll, K.; Manavi, S.; Koch, C.; Olsen, S. R.; Mihalas, S.
10.1101/2020.03.06.977512 — neuroscience — Posted on 2020-03-08
3117 Rbfox contributes to a conservative program of self-antigen splicing in thymic epithelial cells
Jansen, K.; Shikama-Dorn, N.; Attar, M.; Maio, S.; Lopopolo, M.; Buck, D.; Hollander, G. A.; Sansom, S. N.
10.1101/2020.03.06.980870 — immunology — Posted on 2020-03-08
3118 Converting lateral scanning into axial focusing to speed up 3D microscopy
Chakraborty, T.; Chang, B.-J.; Daetwyler, S.; Sapoznik, E.; Chen, B.; Dean, K. M.; Fiolka, R. P.
10.1101/2020.03.06.981472 — bioengineering — Posted on 2020-03-08
3120 Elevated temperatures impose transcriptional constraints on coffee genotypes and elicit intraspecific differences in thermoregulation
de Oliveira, R. R.; Ribeiro, T. H. C.; Cardon, C. H.; Fedenia, L.; Maia, V. A.; Barbosa, B. C. F.; Caldeira, C. F.; Klein, P. E.; Chalfun-Junior, A.
10.1101/2020.03.07.981340 — plant biology — Posted on 2020-03-08
3122 Evidence accumulation and associated error-related brain activity as computationally informed prospective predictors of substance use in emerging adulthood
Weigard, A. S.; Brislin, S. J.; Cope, L. M.; Hardee, J. E.; Martz, M. E.; Ly, A.; Zucker, R. A.; Sripada, C.; Heitzeg, M. M.
10.1101/2020.03.06.981035 — neuroscience — Posted on 2020-03-08
3125 DNA methyltransferase 1 (DNMT1) function is implicated in the age-related loss of cortical interneurons
Hahn, A.; Bayer, C.; Pensold, D.; Tittelmeier, J.; Marx-Bluemel, L.; Gonzalez-Bermudez, L.; Linde, J.; Gross, J.; Salinas-Riester, G.; von Maltzahn, J.; Spehr, M.; Pieler, T.; Urbach, A.; Zimmer-Bensch, G.
10.1101/2020.03.06.981290 — neuroscience — Posted on 2020-03-08
3131 Acute and long-term circuit-level effects in the auditory cortex after sound trauma
Jeschke, M.; Happel, P. D. M. F. K.; Tziridis, K.; Krauss, P.; Schilling, A.; Schulze, H.; Ohl, F. W.
10.1101/2020.03.06.980730 — neuroscience — Posted on 2020-03-08
3132 The mesolimbic dopamine signatures of relapse to alcohol-seeking
Liu, Y.; Jean Richard Dit Bressel, P.; Yau, J. O.-Y.; Willing, A.; Prasad, A. A.; Power, J. M.; Killcross, S.; Clifford, C. W. G.; McNally, G. P.
10.1101/2020.03.06.981605 — neuroscience — Posted on 2020-03-08
3133 Unprecedentedly efficient CUG initiation of an overlapping reading frame in POLG mRNA yields novel protein POLGARF
Loughran, G.; Zhdanov, A. V.; Mikhaylova, M. S.; Rozov, F. N.; Datskevich, P. N.; Kovalchuk, S. I.; Serebryakova, M. V.; Kiniry, S.; Michel, A. M.; O'Connor, P. B.; Papkovsky, D. B.; Atkins, J. F.; Baranov, P. V.; Shatsky, I. N.; Andreev, D. E.
10.1101/2020.03.06.980391 — molecular biology — Posted on 2020-03-08
3134 Contamination of Currency Notes with Kanamycin Resistant Shigella flexneri
Al-Hajj, E. M.; Mohamed, M. S.; Alfadil, N. A. A.; Altayb, H. N.; Idris, A. B.; El-Zaki, S.-E.; Hassan, M. A.
10.1101/2020.03.07.982017 — microbiology — Posted on 2020-03-08
3135 Plasmodium oocysts respond with dormancy to crowding and nutritional stress
Habtewold, T.; Sharma, A. A.; Masters, E. K. G.; Wyer, C. A. S.; Windbichler, N.; Christophides, G.
10.1101/2020.03.07.981951 — microbiology — Posted on 2020-03-08
3138 Long-term homeostatic T cell proliferation is driven by AMPK-dependent regulation of oxygen reactive species
Lepez, A.; Pirnay, T.; Denanglaire, S.; Perez-Morga, D.; Vermeersch, M.; Leo, O.; Andris, F.
10.1101/2020.03.06.978791 — immunology — Posted on 2020-03-08
3141 Landscape drivers and effectiveness of pest control by insectivorous birds in a landscape-dominant woody crop
Martinez-Nunez, C.; Rey, P. J.; Manzaneda, A. J.; Garcia, D.; Tarifa, R.; Molina, J. L.; Salido, M. T.
10.1101/2020.03.07.981845 — ecology — Posted on 2020-03-08
3142 Antibiotic-induced disturbances of the gut microbiota result in accelerated breast tumour growth via a mast cell-dependent pathway
Kirkup, B. M.; McKee, A. M.; Madgwick, M.; Price, C. A.; Dreger, S. A.; Makin, K. A.; Caim, S.; Le Gall, G.; Pavely, J.; Leclaire, C.; Dalby, M.; Alcon-Giner, C.; Andrusaite, A.; Di Modica, M.; Triulzi, T.; Tagliabue, E.; Milling, S. W.; Weilbaecher, K. N.; Korcsmaros, T. D.; Hall, L. J.; Robinson, S. D.
10.1101/2020.03.07.982108 — cancer biology — Posted on 2020-03-08
3146 Short-term exposure to intermittent hypoxia in mice leads to changes in gene expression seen in chronic pulmonary disease
Wu, G.; Lee, Y. Y.; Gulla, E. M.; Potter, A.; Kitzmiller, J.; Ruben, M. D.; Salomonis, N.; Whitsett, J. A.; Francey, L. J.; Hogenesch, J. B.; Smith, D. F.
10.1101/2020.03.06.981241 — pathology — Posted on 2020-03-08
3148 Positioning of nucleosomes containing γ-H2AXprecedes active DNA demethylation and transcription initiation
Dobersch, S.; Rubio, K.; Singh, I.; Guenther, S.; Graumann, J.; Cordero, J.; Castillo-Negrete, R.; Huynh, M. B.; Mehta, A.; Bruabach, P.; Cabrera-Fuentes, H.; Bernhagen, J.; Chao, C.-M.; Bellusci, S.; Guenther, A.; Preissner, K.; Dobreva, G.; Wygrecka, M.; Braun, T.; Papy-Garcia, D.; Barreto, G.
10.1101/2020.03.06.980912 — molecular biology — Posted on 2020-03-08
3149 Structure and function of virion RNA polymerase of crAss-like phage
Drobysheva, A. V.; Panafidina, S. A.; Kolesnik, M. V.; Klimuk, E. I.; Minakhin, L.; Yakunina, M. V.; Borukhov, S.; Nilsson, E.; Holmfeldt, K.; Yutin, N.; Makarova, K. S.; Koonin, E. V.; Severinov, K. V.; Leiman, P. G.; Sokolova, M. L.
10.1101/2020.03.07.982082 — molecular biology — Posted on 2020-03-08
3155 ProGen: Language Modeling for Protein Generation
Madani, A.; McCann, B.; Naik, N.; Keskar, N. S.; Anand, N.; Eguchi, R. R.; Huang, P.; Socher, R.
10.1101/2020.03.07.982272 — synthetic biology — Posted on 2020-03-08
3158 Patterns of functional and structural brain information are preserved over generations
Takagi, Y.; Okada, N.; Ando, S.; Yahata, N.; Morita, K.; Koshiyama, D.; Kawakami, S.; Sawada, K.; Koike, S.; Endo, K.; Yamasaki, S.; Nishida, A.; Kasai, K.; Tanaka, S. C.
10.1101/2020.03.06.981068 — neuroscience — Posted on 2020-03-08
3160 Parallel organization of cerebellar pathways to sensorimotor, associative, and modulatory forebrain
Pisano, T. J.; Dhanerawala, Z. M.; Kislin, M.; Bakshinskaya, D.; Engel, E. A.; Lee, J.; de Oude, N. L.; Umadevi Venkataraju, K.; Verpeut, J. L.; Boele, H.-J.; Wang, S. S.- H.
10.1101/2020.03.06.979153 — neuroscience — Posted on 2020-03-08
3161 A gut sensor for sugar preference
Buchanan, K. L.; Rupprecht, L. E.; Sahasrabudhe, A.; Kaelberer, M. M.; Klein, M. E.; Villalobos, J.; Liu, W. W.; Yang, A.; Gelman, J.; Park, S.; Anikeeva, P.; Bohorquez, D. V.
10.1101/2020.03.06.981365 — neuroscience — Posted on 2020-03-08
3163 Immunogenicity, safety and efficacy of sequential immunizations with an SIV-based IDLV expressing CH505 Envs
Blasi, M.; Negri, D.; Saunders, K. O.; Baker, E. J.; Stadtler, H.; LaBranche, C.; Mildenberg, B.; Morton, G.; Ciarla, A.; Shen, X.; Wang, Y.; Rountree, W.; Balakumaran, B.; Santra, S.; Haynes, B. F.; Moody, A. M.; Cara, A.; Klotman, M. E.
10.1101/2020.03.06.980680 — immunology — Posted on 2020-03-08
3169 Rapid mechanoenzymatic saccharification of lignocellulosic biomass without bulk water or chemical pre-treatment
Hammerer, F.; Ostadjoo, S.; Dietrich, K.; Dumont, M.-J.; Del Rio, L. F.; Friscic, T.; Auclair, K.
10.1101/2020.03.06.980631 — biochemistry — Posted on 2020-03-08
3170 Global Landscape of Native Protein Complexes in Synechocystis sp. PCC 6803
Xu, C.; Wang, B.; Yang, L.; Hu, L. Z.; Yi, L.; Wang, Y.; Chen, S.; Emili, A.; Wan, C.
10.1101/2020.03.07.980128 — biochemistry — Posted on 2020-03-08
3171 High-Throughput Stool Metaproteomics: Method and Application to Human Specimens
Gonzalez, C. G.; Wastyk, H. C.; Topf, M.; Gardner, C. D.; Sonnenburg, J. L.; Elias, J. E.
10.1101/2020.03.06.981712 — systems biology — Posted on 2020-03-08
3172 Distinct Neuronal Populations Contribute to Trace Conditioning and Extinction Learning in the Hippocampal CA1
Mount, R.; Gritton, H. J.; Han, X.; Mohammed, A. I.; Hansen, K. R.; Sridhar, S.; Abdulkerim, M. E.; Kessel, R.; Nazer, B.
10.1101/2020.03.06.980854 — neuroscience — Posted on 2020-03-08
3173 Altered Sensorimotor-to-Transmodal Hierarchical Organization in Schizophrenia
Dong, D.; Yao, D.; Wang, Y.; Hong, S.-J.; Genon, S.; Xin, F.; Jung, K.; He, H.; Chang, X.; Duan, M.; Bernhardt, B.; Margulies, D. S.; Sepulcre, J.; Eickhoff, S. B.; Luo, C.
10.1101/2020.03.06.980607 — neuroscience — Posted on 2020-03-08
3174 The lupus autoantigen La is an Xist-binding RNA chaperone involved in Xist folding and cloud formation
Ha, N.; Ding, N.; Hong, R.; Liu, R.; Roca, X.; Luo, Y.; Duan, X.; Wang, X.; Zhang, L.-F.; Chen, L.
10.1101/2020.03.07.981860 — molecular biology — Posted on 2020-03-08
3175 Role of Specialized mSWI/SNF Complexes in Prostate Cancer Lineage Plasticity
Cyrta, J.; Augspach, A.; de Filippo, M. R.; Prandi, D.; Thienger, P.; Benelli, M.; Cooley, V.; Bareja, R.; Wilkes, D.; Chae, S.-S.; Cavaliere, P.; Dephoure, N.; Uldry, A.-C.; Lagache, S. B.; Cohen, S.; Jaquet, M.; Brandt, L. P.; Alshalalfa, M.; Sboner, A.; Feng, F.; Wang, S.; Beltran, H.; Lotan, T.; Spahn, M.; Kruithof-de Julio, M.; Chen, Y.; Ballman, K. V.; Demichelis, F.; Piscuoglio, S.; Rubin, M.
10.1101/2020.03.06.949131 — cancer biology — Posted on 2020-03-08
3178 Porcupine: Rapid and robust tagging of physical objects using nanopore-orthogonal DNA strands
Doroschak, K. J.; Zhang, K.; Queen, M.; Mandyam, A.; Strauss, K.; Ceze, L. H.; Nivala, J.
10.1101/2020.03.06.981514 — synthetic biology — Posted on 2020-03-08
3183 Genotyping of Russian isolates of fungal pathogen Trichophyton rubrum, based on simple sequence repeat and single nucleotide polymorphism
Pchelin, I. M.; Mochalov, Y. V.; Azarov, D. V.; Romanyuk, S. A.; Chilina, G. A.; Vybornova, I. V.; Bogdanova, T. V.; Zlatogursky, V. V.; Apalko, S. V.; Vasilyeva, N. V.; Taraskina, A. E.
10.1101/2020.03.06.980839 — microbiology — Posted on 2020-03-08
3184 Geological degassing enhances microbial metabolism in the continental subsurface
Bornemann, T. L.; Adam, P. S.; Turzynski, V.; Schreiber, U.; Figueroa-Gonzalez, P. A.; Rahlff, J.; Koester, D.; Schmidt, T. C.; Schunk, R.; Krauthausen, B.; Probst, A. J.
10.1101/2020.03.07.980714 — microbiology — Posted on 2020-03-08
3186 Irgm2 and Gate-16 cooperatively dampen targeting of caspase-11 to Gram-negative bacterial products
Eren, E.; Planes, R.; Bagayoko, S.; Bordignon, P.-J.; Chaoui, K.; Hessel, A.; Santoni, K.; Pinilla, M.; Schiltz, O.; Howard, J. C.; Yamamoto, M.; Meunier, E.
10.1101/2020.03.06.980433 — immunology — Posted on 2020-03-08
3187 locStra: Fast analysis of regional/global stratification in whole genome sequencing (WGS) studies
Hahn, G.; Lutz, S. M.; Hecker, J.; Prokopenko, D.; Cho, M.; Silverman, E. K.; Weiss, S.; Lange, C.
10.1101/2020.03.06.981050 — genetics — Posted on 2020-03-08
3191 Network structure of the mouse brain connectome with voxel resolution
Coletta, L.; Pagani, M.; Whitesell, J. D.; Harris, J. A.; Bernhardt, B.; Gozzi, A.
10.1101/2020.03.06.973164 — neuroscience — Posted on 2020-03-08
3192 Evidence for oligodendrocyte progenitor cell heterogeneity in the adult mouse brain.
Beiter, R. M.; Fernandez-Castaneda, A.; Rivet-Noor, C.; Merchak, A.; Bai, R.; Slogar, E.; Seki, S. M.; Rosen, D. A.; overall, c. c.; Gaultier, A.
10.1101/2020.03.06.981373 — neuroscience — Posted on 2020-03-08
3194 Conjugative dissemination of plasmids in rapid sand filters: a trojan horse strategy to enhance pesticide degradation in groundwater treatment
Pinilla-Redondo, R.; Olsen, A. K.; Russel, J.; de Vries, L. E.; Christensen, L. D.; Musovic, S.; Nesme, J.; Soerensen, S. J.
10.1101/2020.03.06.980565 — microbiology — Posted on 2020-03-08
3197 Frequency-dependent interactions determine outcome of competition between two breast cancer cell lines
Freischel, A. R.; Damaghi, M.; Cunningham, J. J.; Ibrahim-Hashim, A.; Gillies, R. J.; Gatenby, R. A.; Brown, J. S.
10.1101/2020.03.06.979518 — cancer biology — Posted on 2020-03-08
3201 Deep learning-based adaptive detection of fetal nucleated red blood cells
Sun, C.; Wang, R.; Zhao, L.; Han, L.; Ma, S.; Liang, D.; Wang, L.; Tuo, X.; Zhong, D.; Li, Q.
10.1101/2020.03.06.980227 — pathology — Posted on 2020-03-08
3202 Genomic islands of differentiation in a rapid avian radiation have been driven by recent selective sweeps
Hejase, H. A.; Salman-Minkov, A.; Campagna, L.; Hubisz, M. J.; Lovette, I. J.; Gronau, I.; Siepel, A.
10.1101/2020.03.07.977694 — evolutionary biology — Posted on 2020-03-08
3204 Dynamics of protein binding to sites of nascent unscheduled DNA repair synthesis in non-proliferating cells
Scalera, C.; Dutto, I.; Barbazza, F.; Abou Khouzam, R.; Ticli, G.; Cazzalini, O.; Stivala, L. A.; Prosperi, E.
10.1101/2020.03.06.979039 — biochemistry — Posted on 2020-03-08
3207 Cytoskeletal tension forces mitohormesis
Tharp, K. M.; Higuchi-Sanabria, R.; Timblin, G.; Garzon-Coral, C.; Ford, B.; Schneider, C.; Muncie, J. M.; Stashko, C.; Daniele, J.; Frankino, P.; Manoli, S.; Shao, H.; Gestwicki, J.; Hellerstein, M.; Nomura, D. K.; Saijo, K.; Dunn, A.; Dillin, A.; Weaver, V. M.
10.1101/2020.03.06.979583 — cell biology — Posted on 2020-03-08
3210 Isoform cell type specificity in the mouse primary motor cortex
Booeshaghi, A. S.; Yao, Z.; Velthoven, C. v.; Smith, K.; Tasic, B.; Zeng, H.; Pachter, L.
10.1101/2020.03.05.977991 — neuroscience — Posted on 2020-03-08
3212 Missing-In-Metastasis / Metastasis Suppressor 1 modulates B cell receptor signaling, B cell metabolic potential and T cell-independent immune responses.
Sarapulov, A. V.; Petrov, P.; Hernandez-Perez, S.; Sustar, V.; Kuokkanen, E.; Vinod, R.; Vainio, M.; Cords, L.; Fritzsche, M.; Carrasco, Y.; Mattila, P.
10.1101/782276 — immunology — Posted on 2020-03-08
3213 The Division of Amyloid Fibrils - Systematic comparison of fibril fragmentation stability by linking theory with experiments
Beal, D. M.; Tournus, M.; Marchante, R.; Purton, T.; Smith, D. P.; Tuite, M. F.; Doumic, M.; Xue, W.-F.
10.1101/506386 — biophysics — Posted on 2020-03-08
3217 Interplay between historical and current features of the cityscape in shaping the genetic structure of the house mouse (Mus musculus domesticus) in Dakar (Senegal, West Africa)
Stragier, C.; Piry, S.; Loiseau, A.; Kane, M.; Sow, A.; Niang, Y.; Diallo, M.; Ndiaye, A.; Gauthier, P.; Borderon, M.; Granjon, L.; Brouat, C.; Berthier, K.
10.1101/557066 — ecology — Posted on 2020-03-08
3218 A neural m6A/YTHDF pathway is required for learning and memory in Drosophila
Kan, L.; Ott, S.; Joseph, B.; Park, E. S.; Dai, C.; Kleiner, R.; Claridge-Chang, A.; Lai, E. C.
10.1101/2020.03.07.982090 — animal behavior and cognition — Posted on 2020-03-07
3219 Putative ligand binding sites of two functionally characterized bark beetle odorant receptors
Yuvaraj, J. K.; Roberts, R. E.; Sonntag, Y.; Hou, X.; Grosse-Wilde, E.; Machara, A.; Hansson, B. S.; Johanson, U.; Lofstedt, C.; Andersson, M. N.
10.1101/2020.03.07.980797 — neuroscience — Posted on 2020-03-07
3220 Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites
Chen, S.; Kang, S.; Yang, M.; Hong, Z.; Zhang, L.; Huang, Z.; Chen, X.; He, S.; Zhou, Z.; Zhou, Z.; Chen, Q.; Yan, Y.; Zhang, C.; Shan, H.
10.1101/2020.03.06.977876 — molecular biology — Posted on 2020-03-07
3221 Monoclonal antibodies for the S2 subunit of spike of SARS-CoV cross-react with the newly-emerged SARS-CoV-2
Zheng, Z.; Monteil, V. M.; Maurer-Stroh, S.; Yew, C. W.; Leong, C.; Mohd-Ismail, N. K.; Arularasu, S. C.; Chow, V. T. K.; Lin, R. T. P.; Mirazimi, A.; Hong, W.; Tan, Y.-J.
10.1101/2020.03.06.980037 — microbiology — Posted on 2020-03-07
3222 LY6E impairs coronavirus fusion and confers immune control of viral disease
Pfaender, S.; Mar, K. B.; Michailidis, E.; Kratzel, A.; Hirt, D.; V'kovski, P.; Fan, W.; Ebert, N.; Stalder, H.; Kleine-Weber, H.; Hoffmann, M.; Hoffmann, H. H.; Saeed, M.; Dijkman, R.; Steinmann, E.; Wight-Carter, M.; Hanners, N. W.; Pohlmann, S.; Gallagher, T.; Todt, D.; Zimmer, G.; Rice, C. M.; Schoggins, J. W.; Thiel, V.
10.1101/2020.03.05.979260 — microbiology — Posted on 2020-03-07
3226 Direct RNA sequencing and early evolution of SARS-CoV-2
Taiaroa, G.; Rawlinson, D.; Featherstone, L.; Pitt, M.; Caly, L.; Druce, J.; Purcell, D.; Harty, L.; Tran, T.; Roberts, J.; Catton, M.; Williamson, D.; Coin, L.; Duchene, S.
10.1101/2020.03.05.976167 — microbiology — Posted on 2020-03-07
3227 MEK inhibition causes Bim stabilization and sensitivity to Bcl2 family member inhibitors in RAS-MAPK mutated neuroblastoma
Eleveld, T. F.; Vernooij, L.; Schild, L.; Koopmans, B.; Alles, L. K.; Ebus, M. E.; van Sluis, P. G.; Caron, H. N.; Koster, J.; Versteeg, R.; Dolman, E. M.; Molenaar, J. J.
10.1101/2020.02.12.945089 — cancer biology — Posted on 2020-03-07
3228 Bidirectional alterations in antibiotics susceptibility in Staphylococcus aureus - Pseudomonas aeruginosa dual-species biofilm
Kayumov, A. R.; Trizna, E. J.; Yarullina, M. N.; Akhatova, F. S.; Rozhina, E. V.; Fakhrullin, R. F.; Khabibrakhmanova, A. M.; Kurbangalieva, A. R.; Bogachev, M. I.
10.1101/334516 — microbiology — Posted on 2020-03-07
3229 Autoregulation clamps the synaptic membrane-remodeling machinery and promotes productive actin-dependent endocytosis
Del Signore, S. J.; Kelley, C. F.; Messelaar, E. M.; Lemos, T.; Marchan, M. F.; Mund, M.; Kaksonen, M.; Rodal, A. A.
10.1101/2020.03.06.981076 — cell biology — Posted on 2020-03-07
3230 Cytoskeletal tension forces mitohormesis
Tharp, K. M.; Higuchi-Sanabria, R.; Timblin, G.; Garzon-Coral, C.; Ford, B.; Schneider, C.; Muncie, J. M.; Stashko, C.; Daniele, J.; Frankino, P.; Manoli, S.; Shao, H.; Gestwicki, J.; Hellerstein, M.; Nomura, D. K.; Saijo, K.; Dunn, A.; Dillin, A.; Weaver, V. M.
10.1101/2020.03.06.979583 — cell biology — Posted on 2020-03-07
3232 Increased FOXL2 Expression Alters Uterine Structures and Functions
Li, R.; Wu, S.-P.; Zhou, L.; Nicol, B.; Lydon, J. P.; Yao, H. H.-C.; DeMayo, F. J.
10.1101/2020.03.06.981266 — developmental biology — Posted on 2020-03-07
3234 PIP3 depletion rescues myoblast fusion defects in human rhabdomyosarcoma cells
Lian, Y.-L.; Chen, K.-W.; Chou, Y.-T.; Ke, T.-L.; Chen, B.-C.; Lin, Y.-C.; Chen, L.
10.1101/2020.03.06.980706 — cell biology — Posted on 2020-03-07
3235 Mechanosensing through direct binding of tensed F-actin by LIM domains
Sun, X.; Phua, D. Y. Z.; Axiotakis, L.; Smith, M. A.; Blankman, E.; Gong, R.; Cail, R. C.; Espinosa de los Reyes, S.; Beckerle, M. C.; Waterman, C. M.; Alushin, G. M.
10.1101/2020.03.06.979245 — biophysics — Posted on 2020-03-07
3237 Heterogeneity of Neuroepithelial Cells and Radial Glia
Eze, U. C.; Bhaduri, A.; Nowakowski, T. J.; Kriegstein, A. R.
10.1101/2020.03.06.981423 — developmental biology — Posted on 2020-03-07
3241 Characterization of fluorescent proteins with intramolecular photostabilization
Henrikus, S.; Tassis, K.; Zhang, L.; Velde, J. v. d.; Gebhardt, C.; Herrmann, A.; Jung, G.; Cordes, T.
10.1101/2020.03.07.980722 — biophysics — Posted on 2020-03-07
3242 Targeting the water network in cyclin G associated kinase (GAK) with 4-anilino-quin(az)oline inhibitors
Asquith, C. R. M.; Tizzard, G. J.; Bennett, J. M.; Wells, C. I.; Elkins, J. M.; M. Willson, T. M.; Poso, A.; Laitinen, T.
10.1101/2020.03.06.976563 — biochemistry — Posted on 2020-03-07
3243 Mycobacterium tuberculosis Rv0991c is a redox-regulated molecular chaperone
Becker, S. H.; Ulrich, K.; Dhabaria, A.; Ueberheide, B.; Beavers, W. N.; Skaar, E. P.; Iyer, L. M.; Aravind, L.; Jakob, U.; Darwin, K. H.
10.1101/2020.03.05.980086 — microbiology — Posted on 2020-03-07
3246 Genome Report: De novo genome assembly and annotation for the Taita white-eye (Zosterops silvanus)
Engler, J. O.; Lawrie, Y.; Gansemans, Y.; van Nieuwerburgh, F.; Suh, A. O.; Lens, L.
10.1101/2020.03.06.980599 — genomics — Posted on 2020-03-07
3256 External mechanical cues reveal core molecular pathway behind tissue bending in plants
Baral, A.; Morris, E.; Aryal, B.; Jonsson, K.; Verger, S.; Xu, T.; Bennett, M. J.; Hamant, O.; Bhalerao, R. P.
10.1101/2020.03.05.978296 — plant biology — Posted on 2020-03-07
3258 Adult-born hippocampal neurons undergo extended development and are morphologically distinct from neonatally-born neurons
Cole, J. D.; Espinueva, D.; Seib, D. R.; Ash, A. M.; Cooke, M. B.; Cahill, S. P.; O'Leary, T.; Kwan, S. S.; Snyder, J. S.
10.1101/702746 — neuroscience — Posted on 2020-03-07
3260 The gliopeptide ODN, a ligand for the benzodiazepine site of GABAA receptors, boosts functional recovery after stroke
Lamtahri, R.; Hazime, M.; Gowing, E. K.; Nagaraja, R. Y.; Maucotel, J.; Quilichini, P.; Lehongre, K.; Lefranc, B.; Gach-Janczak, K.; Marcher, A.-B.; Mandrup, S.; Vaudry, D.; Clarkson, A.; Leprince, J.; Chuquet, J.
10.1101/2020.03.05.977934 — neuroscience — Posted on 2020-03-07
3261 Astrocytic striatal GABA transporter activity governs dopamine release and shows maladaptive downregulation in early parkinsonism
Roberts, B. M.; Doig, N. M.; Brimblecombe, K. R.; Lopes, E. F.; Siddorn, R. E.; Threlfell, S.; Connor-Robson, N.; Bengoa-Vergniory, N.; Pasternack, N.; Wade-Martins, R.; Magill, P. J.; Cragg, S. J.
10.1101/698274 — neuroscience — Posted on 2020-03-07
3263 Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients
D'Amato, A.; Di Cesare-Mannelli, L.; Lucarini, E.; Man, A. L.; Le Gall, G.; Branca, J. J. V.; Ghelardini, C.; Amedei, A.; Bertelli, E.; Regoli, M.; Pacini, A.; Luciani, G.; Gallina, P.; Altera, A.; Narbad, A.; Gulisano, M.; Hoyles, L.; Vauzour, D.; Nicoletti, C.
10.1101/866459 — neuroscience — Posted on 2020-03-07
3264 Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer
Apostolo, N.; Smukowski, S. N.; Vanderlinden, J.; Condomitti, G.; Rybakin, V.; ten Bos, J.; Trobiani, L.; Portegies, S.; Vennekens, K. M.; Gounko, N. V.; Comoletti, D.; Wierda, K. D.; Savas, J. N.; de Wit, J.
10.1101/846816 — neuroscience — Posted on 2020-03-07
3265 m6A RNA methylation regulates promoter proximal pausing of RNA Polymerase II
Akhtar, J.; Renaud, Y.; Albrecht, S.; Ghavi-Helm, Y.; Roignant, J.-Y.; Silies, M.; Junion, G.
10.1101/2020.03.05.978163 — molecular biology — Posted on 2020-03-07
3266 The dynamic surface proteomes of allergenic fungal conidia
Blango, M. G.; Pschibul, A.; Rivieccio, F.; Krueger, T.; Rafiq, M.; Jia, L.-J.; Zheng, T.; Goldmann, M.; Voltersen, V.; Li, J.; Panagiotou, G.; Kniemeyer, O.; Brakhage, A. A.
10.1101/2020.01.10.902015 — microbiology — Posted on 2020-03-07
3268 Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel, inducing DNA-dissociation via a transmission spine
Lara, J.; Diacovich, L.; Trajtenberg, F.; Larrieux, N.; Malchiodi, E. L.; Fernandez, M. M.; Gago, G.; Gramajo, H.; Buschiazzo, A.
10.1101/2020.03.05.978833 — microbiology — Posted on 2020-03-07
3270 Undinarchaeota illuminate the evolution of DPANN archaea
Dombrowski, N.; Williams, T. A.; Sun, J.; Woodcroft, B. J.; Lee, J.-H.; Minh, B. Q.; Rinke, C.; Spang, A.
10.1101/2020.03.05.976373 — evolutionary biology — Posted on 2020-03-07
3277 Collective interactions augment influenza A virus replication in a host-dependent manner
Phipps, K. L.; Ganti, K.; Jacobs, N. T.; Lee, C.-Y.; Carnacinni, S.; White, M. C.; Manandhar, M.; Pickett, B. E.; Tan, G. S.; Ferreri, L. M.; Perez, D. R.; Lowen, A. C.
10.1101/736108 — microbiology — Posted on 2020-03-07
3278 Leaderless short ORFs in mycobacteria comprise a translational regulon
Canestrari, J. G.; Lasek-Nesselquist, E.; Upadhyay, A.; Rofaeil, M.; Champion, M. M.; Wade, J. T.; Derbyshire, K. M.; Gray, T. A.
10.1101/834739 — microbiology — Posted on 2020-03-07
3281 Zebrafish mbnl mutants model physical and molecular phenotypes of myotonic dystrophy
Hinman, M. N.; Richardson, J. I.; Sockol, R. A.; Aronson, E. D.; Stednitz, S. J.; Murray, K. N.; Berglund, J. A.; Guillemin, K.
10.1101/665380 — molecular biology — Posted on 2020-03-07
3282 A TAL effector-like protein of symbiotic Mycetohabitans increases stress tolerance and alters the transcriptome of the fungal host Rhizopus microsporus
Carter, M. E.; Carpenter, S. C. D.; Dubrow, Z. E.; Sabol, M. R.; Rinaldi, F. C.; Lastovetsky, O. A.; Mondo, S. J.; Pawlowska, T. E.; Bogdanove, A. J.
10.1101/2020.03.04.968529 — microbiology — Posted on 2020-03-07
3286 "Sulcus Sink": A Compact Binary and Semi-Automated Inverse Dijkstra-based System for Describing Sulcal Trajectories
Pienaar, R.; Hasselgrove, C.; Im, K.; Kennedy, D.; Grant, P. E.; Boriel, D.; Tang, L.; Makris, N.
10.1101/2020.02.18.955096 — bioinformatics — Posted on 2020-03-07
3288 Training deep neural density estimators to identify mechanistic models of neural dynamics
Goncalves, P. J.; Lueckmann, J.-M.; Deistler, M.; Nonnenmacher, M.; Öcal, K.; Bassetto, G.; Chintaluri, C.; Podlaski, W. F.; Haddad, S. A.; Vogels, T. P.; Greenberg, D. S.; Macke, J. H.
10.1101/838383 — neuroscience — Posted on 2020-03-07
3290 The developing Human Connectome Project (dHCP) automated resting-state functional processing framework for newborn infants.
Fitzgibbon, S. P.; Harrison, S. J.; Jenkinson, M.; Baxter, L.; Robinson, E. C.; Bastiani, M.; Bozek, J.; Karolis, V.; Cordero Grande, L.; Price, A. N.; Hughes, E.; Makropoulos, A.; Passerat-Palmbach, J.; Schuh, A.; Gao, J.; Farahibozorg, S.-R.; O'Muircheartaigh, J.; Ciarrusta, J.; O'Keeffe, C.; Brandon, J.; Arichi, T.; Rueckert, D.; Hajnal, J. V.; Edwards, A. D.; Smith, S. M.; Duff, E.; Andersson, J.
10.1101/766030 — neuroscience — Posted on 2020-03-07
3291 Isolation and characterization of SARS-CoV-2 from the first US COVID-19 patient
Harcourt, J.; Tamin, A.; Lu, X.; Kamili, S.; Kumar Sakthivel, S.; Wang, L.; Murray, J.; Queen, K.; Lynch, B.; Whitaker, B.; Tao, Y.; Paden, C.; Zhang, J.; Li, Y.; Uehara, A.; Wang, H.; Goldsmith, C.; Bullock, H.; Gautam, R.; Schindewolf, C.; Lokugamage, K. G.; Scharton, D.; Plante, J.; Mirchandani, D.; Widen, S.; Narayanan, K.; Makino, S.; Ksiazek, T.; Plante, K. S.; Weaver, S.; Menachery, V. D.; Thornburg, N. J.
10.1101/2020.03.02.972935 — microbiology — Posted on 2020-03-07
3292 Non-lethal exposure to H2O2 boosts bacterial survival and evolvability against oxidative stress
Rodriguez Rojas, A.; Kim, J.; Johnston, P. R.; Makarova, O.; Eravci, M.; Weise, C.; Hengge, R.; Rolff, J.
10.1101/575134 — evolutionary biology — Posted on 2020-03-07
3296 Comparative proximity biotinylation implicates RAB18 in cholesterol mobilization and biosynthesis
Kiss, R. S.; Chicoine, J.; Khalil, Y.; Sladek, R.; Chen, H.; Pisaturo, A.; Martin, C.; Dale, J. D.; Brudenell, T. A.; Kamath, A.; Paci, E.; Clayton, P.; Wills, J. C.; von Kriegsheim, A.; Nilsson, T.; Sheridan, E.; Handley, M. T.
10.1101/871517 — cell biology — Posted on 2020-03-07
3299 Multistable and dynamic CRISPRi-based synthetic circuits
Santos-Moreno, J.; Tasiudi, E.; Stelling, J.; Schaerli, Y.
10.1101/756338 — synthetic biology — Posted on 2020-03-07
3300 The inflammasome of circulatory collapse: single cell analysis of survival on extracorporeal life support.
Kort, E. J.; Weiland, M.; Grins, E.; Eugster, E.; Milliron, H.-y.; Kelty, C.; Shrestha, N. M.; Timek, T.; Leacche, M.; Fitch, S.; Boeve, T.; Marco, G.; Dickinson, M.; Wilton, P.; Jovinge, S.
10.1101/568659 — genomics — Posted on 2020-03-07
3302 Dynamic localization of SPO11-1 and conformational changes of meiotic axial elements during recombination initiation of maize meiosis
Ku, J.-C.; Ronceret, A.; Golubovskaya, I.; Lee, D. H.; Wang, C.; Timofejeva, L.; Kao, Y.-H.; Angoa, A. K. G.; Kremling, K.; Williams-Carrier, R.; Meeley, R.; Barkan, A.; Cande, W. Z.; Wang, C.-J. R.
10.1101/489278 — cell biology — Posted on 2020-03-07
3304 CELLector: Genomics Guided Selection of Cancer in vitro Models
Najgebauer, H.; Yang, M.; Francies, H. E.; Pacini, C.; Stronach, E. A.; Garnett, M. J.; Saez-Rodriguez, J.; Iorio, F.
10.1101/275032 — bioinformatics — Posted on 2020-03-07
3305 Reactive oxygen species as important regulators of cell division
Qi, W.; Ma, L.; Wang, F.; wang, P.; Wu, J.; Wang, J.; Jin, J.; Sun, W.
10.1101/2020.03.06.980474 — plant biology — Posted on 2020-03-06
3309 The Role of Host Calcium Signaling in Toxoplasma gondii egress
Vella, S. A.; Moore, C. A.; Li, Z.-H.; Hortua Triana, M. A.; Potapenko, E.; Moreno, S. N.
10.1101/2020.03.06.980508 — microbiology — Posted on 2020-03-06
3310 Short-range, orientation-reversing template-switching events occur at a high frequency in the human and yeast genomes
Tremblay-Belzile, S.; Perez Di Giorgio, J. A.; Loubert-Hudon, A.; Verreault, A.; Brisson, N.; Omichinski, J. G.
10.1101/2020.03.06.980458 — genomics — Posted on 2020-03-06
3316 GTP-dependent formation of straight oligomers leads to nucleation of microtubules
Ayukawa, R.; Iwata, S.; Imai, H.; Kamimura, S.; Hayashi, M.; Ngo, K. X.; Minoura, I.; Uchimura, S.; Makino, T.; Shirouzu, M.; Shigematsu, H.; Sekimoto, K.; Gigant, B.; Muto, E.
10.1101/2020.03.05.979989 — biophysics — Posted on 2020-03-06
3319 Wide awake at bedtime? The effects of caffeine on sleep and circadian timing in teenagers - a randomized crossover trial
Reichert, C. F.; Veitz, S.; Buehler, M.; Gruber, G.; Rehm, S.; Rentsch, K.; Garbazza, C.; Meyer, M.; Slawik, H.; Lin, Y.-S.; Weibel, J.
10.1101/2020.03.06.980300 — neuroscience — Posted on 2020-03-06
3320 Tead1 reciprocally regulates adult β-cell proliferation and function
Lee, J.; Liu, R.; Kim, B.; Zhang, Y.; Li, F.; Jagannathan, R.; Yang, P.; Negi, V.; Perez-Garcia, E. M.; Saha, P.; Sabek, O.; Coarfa, C.; Creighton, C.; Huising, M.; Bottino, R.; Ma, K.; Moulik, M.; Yechoor, V.
10.1101/2020.03.05.979450 — molecular biology — Posted on 2020-03-06
3322 Integrating Genomic and Transcriptomic Data to Reveal Genetic Mechanisms Underlying Piao Chicken Rumpless Trait
Wang, Y.-M.; Khederzadeh, S.; Li, S.-R.; Otecko, N. O.; M Irwin, D.; Thakur, M.; Ren, X.-D.; Wang, M.-S.; Wu, D.-D.; Zhang, Y.-P.
10.1101/2020.03.05.978742 — genetics — Posted on 2020-03-06
3325 An Endocytic Capture Model for Skeletal Muscle T-tubule Formation
Hall, T. E.; Martel, N.; Ariotti, N.; Xiong, Z.; Lo, H. P.; Ferguson, C. E.; Rae, J.; Lim, Y.-W.; Parton, R. G.
10.1101/2020.03.05.979666 — cell biology — Posted on 2020-03-06
3326 The combination of mitogenic stimulation and cell cycle arrest induces senescence in equine and human cartilage explants
Copp, M. E.; Flanders, M. C.; Gagliardi, R.; Gilbertie, J. M.; Sessions, G. A.; Chubinskaya, S.; Loeser, R. F.; Schnabel, L. V.; Diekman, B. O.
10.1101/2020.03.05.979872 — cell biology — Posted on 2020-03-06
3328 AI boosted molecular MRI for apoptosis detection in oncolytic virotherapy
Perlman, O.; Ito, H.; Herz, K.; Shono, N.; Nakashima, H.; Zaiss, M.; Chiocca, E. A.; Cohen, O.; Rosen, M. S.; Farrar, C. T.
10.1101/2020.03.05.977793 — biophysics — Posted on 2020-03-06
3330 Axial Elongation of Caudalized Human Pluripotent Stem Cell Organoids Mimics Neural Tube Development
Libby, A. R. G.; Joy, D. A.; Elder, N. H.; Bulger, E. A.; Krakora, M. Z.; Gaylord, E. A.; Mendoza-Camacho, F.; McDevitt, T. C.
10.1101/2020.03.05.979732 — bioengineering — Posted on 2020-03-06
3331 Cell-free styrene biosynthesis at high titers
Grubbe, W. S.; Rasor, B. J.; Kruger, A.; Jewett, M. C.; Karim, A. S.
10.1101/2020.03.05.979302 — synthetic biology — Posted on 2020-03-06
3332 Ptr1 evolved convergently with RPS2 and Mr5 to mediate recognition of AvrRpt2 in diverse solanaceous species
Mazo-Molina, D. C.; Mainiero, S.; Haefner, B. J.; Bednarek, R.; Zhang, J.; Feder, A.; Shi, K.; Strickler, S.; Martin, G. B.
10.1101/2020.03.05.979484 — plant biology — Posted on 2020-03-06
3334 Optimization of psoriasis like mouse models: A comparative study
Karamani, C.; Antoniadou, I. T.; Dimou, A.; Andreou, E.; Kostakis, G.; Sideri, A.; Vitsos, A.; Gkavanozi, A.; Sfiniadakis, I.; Skaltsa, H.; Papaioannou, G. T.; Maibach, H.; Rallis, M.
10.1101/2020.03.05.978775 — pharmacology and toxicology — Posted on 2020-03-06
3335 A comprehensive proteomic SWATH-MS workflow for profiling blood extracellular vesicles: a new avenue for glioma tumour surveillance
Hallal, S.; Azimi, A.; Wei, H.; Ho, N.; Lee, M.; Sim, H.-W.; Sy, J.; Shivalingam, B.; Buckland, M. E.; Kaufman, K. L.
10.1101/2020.03.05.979716 — pathology — Posted on 2020-03-06
3336 Fronto-striatal projections regulate approach-avoidance conflict
Loewke, A. C.; Minerva, A. R.; Nelson, A. B.; Kreitzer, A. C.; Gunaydin, L. A.
10.1101/2020.03.05.979708 — neuroscience — Posted on 2020-03-06
3337 Neuron-specific increase in lamin B1 disrupts nuclear function in Huntington's disease
Alcala-Vida, R.; Garcia-Forn, M.; Creus-Muncunill, J.; Ito, Y.; Blanco, E.; Castany-Pladevall, C.; Crespi-Vazquez, K.; Parry, A.; Slater, G.; Samarajiwa, S.; Peiro, S.; Di Croce, L.; Narita, M.; Perez-Navarro, E.
10.1101/2020.03.06.979674 — neuroscience — Posted on 2020-03-06
3338 Choices Change the Temporal Weighting of Decision Evidence
Talluri, B. C.; Urai, A. E.; Bronfman, Z. Z.; Brezis, N.; Tsetsos, K.; Usher, M.; Donner, T. H.
10.1101/2020.03.06.979690 — neuroscience — Posted on 2020-03-06
3341 Mechanism of BceAB-type transporter: Resistance by lipid II flipping
Zaschke-Kriesche, J.; Unsleber, S.; Voitsekhovskaia, I.; Kulik, A.; Behrmann, L.; Overbeck, N.; Stuehler, K.; Stegmann, E.; Smits, S.
10.1101/2020.03.05.978734 — microbiology — Posted on 2020-03-06
3347 Population genetic structure in the insular Ryukyu flying fox, Pteropus dasymallus
Chen, S.-F.; Juan, C.-H.; Rossiter, S.; Kinjo, T.; Fukui, D.; Kawai, K.; Tsang, S. M.; Veluz, M. J.; Jang-Liaw, N.-H.; Osawa, K.; Ko, W.-Y.; Izawa, M.
10.1101/2020.03.05.979211 — ecology — Posted on 2020-03-06
3348 Platelet counts predict prognosis in IPF, but are not the main source of pulmonary TGFβ1
Chong, D. L. W.; Mikolasch, T. A.; Sahota, J.; Rebeyrol, C.; Garthwaite, H. S.; Booth, H. L.; Heightman, M.; Jose, R.; Khawaja, A. A.; Labelle, M.; Scotton, C. J.; Porter, J. C.
10.1101/2020.03.06.978874 — cell biology — Posted on 2020-03-06
3349 Molecular characterization of clonal human renal forming cells
Cohen-Zontag, O.; Gershon, R.; Harari-Steinberg, O.; Kanter, I.; Omer, D.; Pleniceanu, O.; Tam, G.; Oriel, S.; Ben-Hur, H.; Katz, G.; Zohar, D.; Kalisky, T.; Dekel, B.; Pode-Shakked, N.
10.1101/2020.03.05.978254 — cell biology — Posted on 2020-03-06
3351 Optimised use of Oxford Nanopore Flowcells for Hybrid Assemblies
Lipworth, S.; Pickford, H.; Sanderson, N. D.; Chau, K.; Kavanagh, J.; Barker, L.; Vaughan, A.; Swann, J.; Andersson, M.; Jeffery, K. J.; Morgan, M.; Peto, T. E.; Crook, D. W.; Stoesser, N.; Walker, A. S.
10.1101/2020.03.05.979278 — bioinformatics — Posted on 2020-03-06
3353 Bridging the gap: Using reservoir ecology and human serosurveys to estimate Lassa virus incidence in West Africa
Basinski, A. J.; Fichet-Calvet, E. J.; Sjodin, A. R.; Varrelman, T. J.; Remien, C.; Layman, N. C.; Bird, B. H.; Wolking, D. J.; Monagin, C.; Ghersi, B. M.; Barry, P. A.; Jarvis, M. A.; Gessler, P. E.; Nuismer, S. L.
10.1101/2020.03.05.979658 — ecology — Posted on 2020-03-06
3356 Discovery and Predictive Modeling of Urine Microbiome, Metabolite and Cytokine Biomarkers in Hospitalized Patients with Community Acquired Pneumonia
Pierre, J. F.; Akbilgic, O.; Smallwood, H.; Cao, X.; Fitzpatrick, E. A.; Pena, S.; Furmanek, S. P.; Ramirez, J. A.; Jonsson, C. B.
10.1101/2020.03.05.979427 — systems biology — Posted on 2020-03-06
3360 Tracking the outbreak. An optimized delimiting survey strategy for Xylella fastidiosa.
Lazaro, E.; Sese, M.; Lopez-Quilez, A.; Conesa, D.; Dalmau, V.; Ferrer-Matoses, A.; Vicent, A.
10.1101/2020.03.05.978668 — pathology — Posted on 2020-03-06
3362 Medial temporal atrophy in preclinical dementia: visual and automated assessment during six year follow-up
Mårtensson, G.; Håkansson, C.; Pereira, J. B.; Palmqvist, S.; Hansson, O.; van Westen, D.; Westman, E.
10.1101/2020.03.05.979229 — neuroscience — Posted on 2020-03-06
3364 A ventral striatal-orexin/hypocretin circuit modulates approach but not consumption of food.
Mitchell, C. S.; Fisher, S. D.; Yeoh, J. W.; Pearl, A. J.; Burton, N. J.; Bains, J. S.; McNally, G. P.; Andrews, Z. A.; Graham, B. A.; Dayas, C. V.
10.1101/2020.03.05.979468 — neuroscience — Posted on 2020-03-06
3366 Ankhd1 enhances polycystic kidney disease development via promoting proliferation and fibrosis.
Patera, F.; Hautbergue, G. M.; Wilson, P. D.; Evans, P. C.; Ong, A. C.; Fragiadaki, M.
10.1101/2020.03.04.977017 — molecular biology — Posted on 2020-03-06
3367 A porcine bimicrobial abscess model for testing interventional treatments
Wang, Y.-N.; Brayman, A. A.; Chan, K. T.; Richmond, K.; Monsky, W.; Matula, T.
10.1101/2020.03.05.979088 — microbiology — Posted on 2020-03-06
3368 Host population diversity as a driver of viral infection cycle in wild populations of green sulfur bacteria with long standing virus-host interactions
Berg, M.; Goudeau, D.; Olmsted, C.; McMahon, K. D.; Thweatt, J.; Bryant, D.; Eloe-Fadrosh, E. A.; Malmstrom, R. R.; Roux, S.
10.1101/2020.03.05.979559 — microbiology — Posted on 2020-03-06
3369 Only 40% of the world's forests are in good health
Grantham, H. S.; Duncan, A.; Evans, T. D.; Jones, K. R.; Beyer, H.; Schuster, R.; Walston, J.; Ray, J.; Robinson, J.; Callow, M.; Clements, T.; Costa, H.; DeGemmis, A.; Elsen, P. R.; Ervin, J.; Franco, P.; Goldman, E.; Goetz, S.; Hansen, A.; Hofsvang, E.; Jantz, P.; Jupiter, S.; Kang, A.; Langhammer, P.; Laurance, W. F.; Liberman, S.; Linkie, M.; Malhi, Y.; Maxwell, S. L.; Mendez, M.; Mittermeier, R.; Murray, N.; Possingham, H.; Radachowsky, J.; Samper, C.; Silverman, J.; Shapiro, A.; Strassburg, B.; Stevens, T.; Stokes, E.; Taylor, R.; Tear, T.; Tizard, R.; Venter, O.; Visconti, P.; Wang, S.;
10.1101/2020.03.05.978858 — ecology — Posted on 2020-03-06
3373 Ancestry adjustment improves genome-wide estimates of regional intolerance
hayeck, t. j.; Stong, N.; Baugh, E.; Dhindsa, R.; Turner, T. N.; Malakar, A.; Duan, Y.; Ionita-Laza, I.; Goldstein, D.; Andrew Allen, A. S.
10.1101/2020.03.05.979203 — genetics — Posted on 2020-03-06
3374 Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel, inducing DNA-dissociation via a transmission spine
Lara, J.; Diacovich, L.; Trajtenberg, F.; Larrieux, N.; Malchiodi, E. L.; Fernandez, M. M.; Gago, G.; Gramajo, H.; Buschiazzo, A.
10.1101/2020.03.05.978833 — microbiology — Posted on 2020-03-06
3376 Pex24 and Pex32 tether peroxisomes to the ER for organelle biogenesis, positioning and segregation
Wu, F.; de Boer, R.; Krikken, A. M.; Aksit, A.; Bordin, N.; Devos, D. P.; van der Klei, I. J.
10.1101/2020.03.05.977884 — cell biology — Posted on 2020-03-06
3377 Prolonged deficit of gamma oscillations in the peri-infarct cortex of mice after stroke
Hazime, M.; Alasoadura, M.; Lamtahri, R.; Quilichini, P.; Leprince, J.; Vaudry, D.; Chuquet, J.
10.1101/2020.03.05.978593 — neuroscience — Posted on 2020-03-06
3378 In vivo imaging of the kinetics of microglial self-renewal and maturation in the adult visual cortex
Mendes, M. S.; Atlas, J.; Brehm, Z.; Ladron de Guevara Ruiz, A.; McCall, M.; Majewska, A.
10.1101/2020.03.05.977553 — neuroscience — Posted on 2020-03-06
3379 The paradoxical effects of K+ channel gain-of-function are mediated by GABAergic neuron hypoexcitability and hyperconnectivity.
Shore, A. N.; Colombo, S.; Tobin, W. F.; Petri, S.; Cullen, E. R.; Dominguez, S.; Bostick, C.; Beaumont, M.; Williams, D.; Khodagholy, D.; Yang, M.; Lutz, C. M.; Peng, Y.; Gelinas, J. N.; Goldstein, D. B.; Boland, M. J.; Frankel, W. N.; Weston, M. C.
10.1101/2020.03.05.978841 — neuroscience — Posted on 2020-03-06
3380 Evaluating aroA gene essentiality and EPSP synthase vulnerability in Mycobacterium smegmatis under different nutritional conditions
Duque-Villegas, M. A.; Abbadi, B. L.; Romero, P. R.; Galina, L.; Dalberto, P. F.; Rodrigues-Junior, V. S.; Roth, C. D.; Rambo, R. S.; de Souza, E. V.; Perello, M. A.; Machado, P.; Basso, L. A.; Bizarro, C. V.
10.1101/2020.03.02.974360 — microbiology — Posted on 2020-03-06
3381 Functional delineation of tissue-resident CD8 T cell heterogeneity during infection and cancer
Milner, J. J.; Toma, C.; He, Z.; Kurd, N. S.; Nguyen, Q. P.; McDonald, B.; Quezada, L.; Widjaja, C. E.; Witherden, D. A.; Crowl, J. T.; Yeo, G. W.; Chang, J. T.; Omilusik, K. D.; Goldrath, A. W.
10.1101/2020.03.05.979146 — immunology — Posted on 2020-03-06
3383 The critical immunosuppressive effect of MDSC-derived exosomes in the tumor microenvironment.
Rashid, M. H.; Borin, T. F.; Ara, R.; Piranlioglu, R.; Achyut, B. R.; Korkaya, H.; Liu, Y.; Arbab, A. S.
10.1101/2020.03.05.979195 — cancer biology — Posted on 2020-03-06
3386 Space-time logic of liver gene expression at sublobular scale
Droin, C.; El Kholtei, J.; Bahar Halpern, K.; Hurni, C.; Rozenberg, M.; Muvkadi, S.; Itzkovitz, S.; Naef, F.
10.1101/2020.03.05.976571 — systems biology — Posted on 2020-03-06
3387 Model-based design and analysis of life table experiments for insect vectors
Erguler, K.; Demirok, M. C.; Gunay, F.; Petric, M.; Kavran, M.; Petric, D. V.; Alten, B.
10.1101/2020.03.05.978684 — ecology — Posted on 2020-03-06
3388 High throughput functional variant screens via in-vivo production of single-stranded DNA
Schubert, M. G.; Goodman, D. B.; Wannier, T. M.; Kaur, D.; Farzadfard, F.; Lu, T. K.; Shipman, S. L.; Church, G. M.
10.1101/2020.03.05.975441 — synthetic biology — Posted on 2020-03-06
3389 External mechanical cues reveal core molecular pathway behind tissue bending in plants
Baral, A.; Morris, E.; Aryal, B.; Jonsson, K.; Verger, S.; Xu, T.; Bennett, M. J.; Hamant, O.; Bhalerao, R. P.
10.1101/2020.03.05.978296 — plant biology — Posted on 2020-03-06
3392 Dentate gyrus population activity during immobility drives formation of precise memories
Pofahl, M.; Nikbakht, N.; Haubrich, A. N.; Nguyen, T.; Masala, N.; Braganza, O.; Macke, J. H.; Ewell, L. A.; Golcuk, K.; Beck, H.
10.1101/2020.03.05.978320 — neuroscience — Posted on 2020-03-06
3393 Active Vision in Immersive, 360° Real-World Environments
Haskins, A. J.; Mentch, J.; Botch, T. L.; Robertson, C. E.
10.1101/2020.03.05.976712 — neuroscience — Posted on 2020-03-06
3395 A functional RNA structure in the influenza A virus ribonucleoprotein complex for segment bundling
Takizawa, N.; Higashi, K.; Kawaguchi, R. K.; Gotoh, Y.; Suzuki, Y.; Hayashi, T.; Kurokawa, K.
10.1101/2020.03.05.975870 — microbiology — Posted on 2020-03-06
3396 Crude Necator americanus worm extract diminishes pancreatic islets destruction in diabetic non-obese mice (NOD)
Gaze, S.; Velikkakam, T.; Araujo, B. G.; Alves, E. A. R.; Fujiwara, R.; Bueno, L. L.; Fiuza, J. A.
10.1101/2020.03.03.975953 — immunology — Posted on 2020-03-06
3397 Exploring the evolution and adaptive role of mosaic aneuploidy in a clonal Leishmania donovani population using high throughput single-cell genome sequencing
Negreira, G. H.; Monsieurs, P.; Imamura, H.; Maes, I.; Kuk, N.; Yagoubat, A.; Van den Broeck, F.; Sterkers, Y.; Dujardin, J.-C.; Domagalska, M. A.
10.1101/2020.03.05.976233 — genomics — Posted on 2020-03-06
3398 Extreme phenotypes define epigenetic and metabolic signatures in cardiometabolic syndrome.
Seyres, D.; Cabassi, A.; Lambourne, J. J.; Burden, F.; Farrow, S.; McKinney, H.; Batista, J.; Kempster, C.; Pietzner, M.; Slingsby, O.; Cao, T. H.; Quinn, P.; Stefanucci, L.; Sims, M. C.; Rehnstrom, K.; Adams, C.; Frary, A.; Erguener, B.; Kreuzhuber, R.; Mocciaro, G.; Allison, M.; D'Amore, S.; Koulman, A.; Grassi, L.; Griffin, J. L.; Ng, L. L.; Park, A.; Savage, D. B.; Langenberg, C.; Bock, C.; Downes, K.; Vacca, M.; Kirk, P. D.; Frontini, M.
10.1101/2020.03.06.961805 — genomics — Posted on 2020-03-06
3399 mrMLM v4.0: An R Platform for Multi-locus Genome-wide Association Studies
Zhang, Y.-W.; Tamba, C. L.; Wen, Y.-J.; Li, P.; Ren, W.-L.; Ni, Y.-L.; Gao, J.; Zhang, Y.-M.
10.1101/2020.03.04.976464 — genetics — Posted on 2020-03-06
3401 Strong effect of Penicillium roqueforti populations on volatile and metabolic compounds responsible for aromas, flavour and texture in blue cheeses
Caron, T.; Le Piver, M.; Peron, A.-C.; Lieben, P.; Lavigne, R.; Brunel, S.; Roueyre, D.; Place, M.; Bonnarme, P.; Giraud, T.; Branca, A.; Landaud, S.; Chassard, C.
10.1101/2020.03.02.974352 — evolutionary biology — Posted on 2020-03-06
3404 Phenotype Prediction using a Tensor Representation and Deep Learning from Data Independent Acquisition Mass Spectrometry
Zhang, F.; Yu, S.; Wu, L.; Zang, Z.; Yi, X.; Zhu, J.; Lu, C.; Sun, P.; Sun, Y.; Selvarajan, S.; Chen, L.; Teng, X.; Zhao, Y.; Wang, G.; Xiao, J.; Huang, S.; Kon, O. L.; Iyer, G. N.; Li, S. Z.; Luan, Z.; Guo, T.
10.1101/2020.03.05.978635 — bioinformatics — Posted on 2020-03-06
3405 Quantifying flight aptitude variation in wild A. gambiae s.l. in order to identify long-distance migrants
Faiman, R.; Yaro, A. S.; Diallo, M.; Dao, A.; Samake, D.; Sanogo, Z. L.; Sullivan, M.; Krishna, A.; Krajacich, B. B.; Lehmann, T.
10.1101/2020.03.03.975243 — ecology — Posted on 2020-03-06
3407 The antitumoral activity of TLR7 ligands is corrupted by the microenvironment of pancreatic tumors
Rouanet, M.; Lulka, H.; Garcin, P.; Sramek, M.; Pagan, D.; Valle, C.; Sarot, E.; Pancaldi, V.; Lopez, F.; Buscail, L.; Cordelier, P.
10.1101/2020.03.05.978767 — cancer biology — Posted on 2020-03-06
3408 Resident and elicited macrophages differ in expression of their glycomes and lectins
Park, D. D.; Chen, J.; Kudelka, M.; Jia, N.; Haller, C.; Kosaraju, R.; Premji, A.; Galizzi, M.; Nairn, A.; Moreman, K.; Cummings, R. D.; Chaikof, E. L.
10.1101/2020.03.05.975763 — biochemistry — Posted on 2020-03-06
3409 Targeted Esterase induced Dye loading supports Calcium Imaging in Eukaryotic Cell-Free Systems
Dhandapani, P.; Dondapati, S. K.; Zemella, A.; Bräuer, D.; Wüstenhagen, D. A.; Kubick, S.
10.1101/2020.03.05.978247 — biochemistry — Posted on 2020-03-06
3412 Frontotemporal Coordination Predicts Working Memory Performance and its Local Neural Signatures
Rezayat, E.; Dehaqani, M.-R. A.; Clark, K. L.; Bahmani, Z.; Moore, T.; Noudoost, B.
10.1101/2020.03.05.976928 — neuroscience — Posted on 2020-03-06
3413 Differentiation drives widespread rewiring of the neural stem cell chaperone network
Vonk, W. I. M.; Rainbolt, T. K.; Dolan, P. T.; Webb, A. E.; Brunet, A.; Frydman, J.
10.1101/2020.03.05.976068 — molecular biology — Posted on 2020-03-06
3414 Contrasted gene decay in subterranean vertebrates: insights from cavefishes and fossorial mammals
Policarpo, M.; Fumey, J.; Lafargeas, P.; Naquin, D.; Thermes, C.; Naville, M.; Dechaud, C.; Volff, J.-N.; Cabau, C.; Klopp, C.; Rask Moller, P.; Bernatchez, L.; Garcia-Machado, E.; Retaux, S.; Casane, D.
10.1101/2020.03.05.978213 — evolutionary biology — Posted on 2020-03-06
3415 Differential roles of pyramidal and fast-spiking, GABAergic neurons in the control of glioma cell proliferation
Tantillo, E.; Vannini, E.; Cerri, C.; Spalletti, C.; Colistra, A.; Mazzanti, C. M.; Costa, M.; Caleo, M.
10.1101/2020.03.05.978825 — cancer biology — Posted on 2020-03-06
3417 Exploring the upper pH limits of nitrite oxidation: diversity, ecophysiology, and adaptive traits of haloalkalitolerant Nitrospira
Daebeler, A.; Kitzinger, K.; Koch, H.; Herbold, C. W.; Steinfeder, M.; Schwarz, J.; Zechmeister, T.; Karst, S. M.; Albertsen, M.; Nielsen, P. H.; Wagner, M.; Daims, H.
10.1101/2020.03.05.977850 — microbiology — Posted on 2020-03-06
3424 Organ-restricted vascular delivery of nanoparticles for lung cancer therapy
Bolukbas, D. A.; Datz, S.; Meyer-Schwickerath, C.; Morrone, C.; Doryab, A.; Goessl, D.; Vreka, M.; Yang, L.; Argyo, C.; van Rijt, S. H.; Lindner, M.; Eickelberg, O.; Stoeger, T.; Schmid, O.; Lindstedt, S.; Stathopoulos, G. T.; Bein, T.; Wagner, D. E.; Meiners, S.
10.1101/2020.03.05.969212 — pharmacology and toxicology — Posted on 2020-03-06
3425 Synergic effect of optogenetic stimulation and motor training boosts recovery of motor functionality after stroke supported by segregation of motor representation
Conti, E.; ALLEGRA mascaro, A. L.; Scaglione, A.; de Vito, G.; Calugi, F.; Pasquini, M.; Pizzorusso, T.; Micera, S.; Pavone, F. S.
10.1101/2020.03.05.974972 — neuroscience — Posted on 2020-03-06
3427 Intraepithelial T cells diverge by intestinal location as pigs age
Wiarda, J. E.; Trachsel, J. M.; Bond, Z. F.; Byrne, K. A.; Gabler, N. K.; Loving, C. L.
10.1101/2020.03.05.973248 — immunology — Posted on 2020-03-06
3428 Massively parallel single-cell genome sequencing enables high-resolution analysis of soil and marine microorganisms
Nishikawa, Y.; Kogawa, M.; Hosokawa, M.; Mineta, K.; Takahashi, K.; Sakanashi, C.; Behzad, H.; Gojobori, T.; Takeyama, H.
10.1101/2020.03.05.962001 — genomics — Posted on 2020-03-06
3429 An active chromatin interactome elucidates the biological mechanisms underlying genetic risk factors of dermatological conditions in disease relevant cell lines
Shi, C.; Ray-Jones, H.; Ding, J.; Duffus, K.; Fu, Y.; Gaddi, V. P.; Gough, O.; Hankinson, J.; Martin, P.; Mcgovern, A.; Yarwood, A.; Gaffney, P.; Eyre, S.; Rattray, M.; Warren, R.; Orozco, G.
10.1101/2020.03.05.973271 — genomics — Posted on 2020-03-06
3431 Virtual-SMLM, a virtual environment for real-time interactive SMLM acquisition
Griffie, J.; Pham, T.-A. M.; Sieben, C.; Lang, R.; Cevher, V.; Holden, S.; Unser, M.; Manley, S.; Sage, D.
10.1101/2020.03.05.967893 — biophysics — Posted on 2020-03-06
3432 Emergent behavioral organization in heterogeneous groups of a social insect
Ulrich, Y.; Kawakatsu, M.; Tokita, C. K.; Saragosti, J.; Chandra, V.; Tarnita, C. E.; Kronauer, D. J.
10.1101/2020.03.05.963207 — animal behavior and cognition — Posted on 2020-03-06
3436 Benchmarking of computational error-correction methods for next-generation sequencing data
Mitchell, K.; Brito, J.; Mandric, I.; Wu, Q.; Knyazev, S.; Chang, S.; Martin, L. S.; Karlsberg, A.; Gerasimov, E.; Littman, R.; Hill, B. L.; Wu, N. C.; Yang, H.; Hsieh, K.; Chen, L.; Littman, E.; Shabani, T.; Shabanets, G.; Yao, D.; Sun, R.; Schroeder, J.; Eskin, E.; Zelikovsky, A.; Skums, P.; Pop, M.; Mangul, S.
10.1101/642843 — bioinformatics — Posted on 2020-03-06
3439 More than a feeling: central amygdala mediates social transfer of information about proximity of danger
Andraka, K.; Kondrakiewicz, K.; Rojek-Sito, K.; Ziegart-Sadowska, K.; Meyza, K.; Nikolaev, T.; Hamed, A.; Kursa, M.; Wojcik, M.; Danielewski, K.; Wiatrowska, M.; Kublik, E.; Bekisz, M.; Lebitko, T.; Duque, D.; Jaworski, T.; Madej, H.; Konopka, W.; Boguszewski, P. M.; Knapska, E.
10.1101/2020.02.28.969113 — neuroscience — Posted on 2020-03-06
3440 Temporal learning among prefrontal and striatal ensembles
Emmons, E. B.; Chiuffa Tunes, G.; Choi, J.; Bruce, R. A.; Weber, M.; Kim, Y.; Narayanan, N.
10.1101/2020.02.28.970053 — neuroscience — Posted on 2020-03-06
3441 Isoform specificity in the mouse primary motor cortex
Booeshaghi, A. S.; Yao, Z.; Velthoven, C. v.; Smith, K.; Tasic, B.; Zeng, H.; Pachter, L.
10.1101/2020.03.05.977991 — neuroscience — Posted on 2020-03-06
3442 TET1-mediated DNA hydroxy-methylation regulates adult remyelination
Moyon, S.; Frawley, R.; Marshall-Phelps, K. L.; Kegel, L.; Bostrand, S. M.; Sadowski, B.; Huang, D.; Jiang, Y.-H.; Lyons, D.; Mobius, W.; Casaccia, P.
10.1101/819995 — neuroscience — Posted on 2020-03-06
3443 The tRNA pseudouridine synthase TruB1 regulates the maturation and function of let-7 miRNA
Kurimoto, R.; Chiba, T.; Ito, Y.; Matsushima, T.; Yano, Y.; Miyata, K.; Suzuki, T.; Tomita, K.; Asahara, H.
10.1101/2020.02.16.951954 — molecular biology — Posted on 2020-03-06
3444 The γ-herpesviral TATA box binding protein directly interacts with RNA Polymerase II to direct late gene transcription
Castaneda, A. F.; Didychuk, A. L.; Louder, R. K.; McCollum, C. O.; Davis, Z. H.; Nogales, E.; Glaunsinger, B.
10.1101/2020.01.28.922526 — molecular biology — Posted on 2020-03-06
3445 Streptococcus pyogenes M1T1 variants activate caspase-1 and induce an inflammatory neutrophil phenotype
Williams, J. G.; Ly, D.; Geraghty, N. J.; McArthur, J. D.; Vyas, H.; Gorman, J.; Tsatsaronis, J. A.; Sluyter, R.; Sanderson-Smith, M. L.
10.1101/2020.03.02.972240 — microbiology — Posted on 2020-03-06
3446 A novel bat coronavirus reveals natural insertions at the S1/S2 cleavage site of the Spike protein and a possible recombinant origin of HCoV-19
Zhou, H.; Chen, X.; Hu, T.; Li, J.; Song, H.; Liu, Y.; Wang, P.; Liu, D.; Yang, J.; Holmes, E. C.; Hughes, A. C.; Bi, Y.; Shi, W.
10.1101/2020.03.02.974139 — microbiology — Posted on 2020-03-06
3448 Functional pangenome analysis suggests inhibition of the protein E as a readily available therapy for COVID-2019.
Alam, I.; Kamau, A. K.; Kulmanov, M.; Arold, S. T.; Pain, A. T.; Gojobori, T.; Duarte, C. M.
10.1101/2020.02.17.952895 — genomics — Posted on 2020-03-06
3451 Plagues of Desert Locust: No invasion risk to China
Wang, Y.-P.; Wu, M.-F.; Lin, P.-J.; Wang, Y.; Chen, A.-D.; Jiang, Y.-Y.; Zhai, B.-P.; Chapman, J. W.; Hu, G.
10.1101/2020.03.03.973834 — ecology — Posted on 2020-03-06
3452 Exposure to Mites Sensitizes Intestinal Stem Cell Maintenance, Splenic Marginal Zone B Cell Homeostasis, And Heart Development to Notch Dosage and Cooperativity.
Kobia, F. M.; Preusse, K.; Dai, Q.; Weaver, N.; Chaturvedi, P.; Stein, S. J.; Pear, W.; Yuan, Z.; Kovall, R.; Kuang, Y.; Eafergen, N.; Sprinzak, D.; Gebelein, B.; Brunskill, E. W.; Kopan, R.
10.1101/2020.02.13.948224 — developmental biology — Posted on 2020-03-06
3455 Improvement of cryo-EM maps by density modification
Terwilliger, T. C.; Ludtke, S. J.; Read, R. J.; Adams, P. D.; Afonine, P. V.
10.1101/845032 — biochemistry — Posted on 2020-03-06
3460 Gut Microbiome Profiling of a Rural and Urban South African Cohort Reveals Biomarkers of a Population in Lifestyle Transition
Oduaran, O. H.; Tamburini, F. B.; Sahibdeen, V.; Brewster, R.; Gomez-Olive, F. X.; Kahn, K.; Norris, S. A.; Tollman, S. M.; Twine, R.; Wade, A. N.; Wagner, R. G.; Lombard, Z.; Bhatt, A. S.; Hazelhurst, S.
10.1101/2020.02.27.964023 — microbiology — Posted on 2020-03-06
3464 Inducible transgene expression in PDX models in vivo identifies KLF4 as therapeutic target for B-ALL
Liu, W.-H.; Mrozek-Gorska, P.; Herold, T.; Schwarzkopf, L.; Pich, D.; Völse, K.; Wirth, A.-K.; Melo-Narvaez, M. C.; Carlet, M.; Hammerschmidt, W.; Jeremias, I.
10.1101/737726 — cancer biology — Posted on 2020-03-06
3466 Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism
Gaubitz, C.; Liu, X.; Magrino, J.; Stone, N. P.; Landeck, J.; Hedglin, M.; Kelch, B. A.
10.1101/2020.02.18.953257 — biochemistry — Posted on 2020-03-06
3468 Extensive genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm
Doyle, S. R.; Tracey, A.; Laing, R.; Holroyd, N.; Bartley, D.; Bazant, W.; Beasley, H.; Beech, R.; Britton, C.; Brooks, K.; Chaudhry, U.; Maitland, K.; Martinelli, A.; Noonan, J. D.; Paulini, M.; Quail, M. A.; Redman, E.; Rodgers, F. H.; Salle, G.; Sankaranarayanan, G.; Shabbir, M. Z.; Wit, J.; Howe, K. L.; Sargison, N.; Devaney, E.; Berriman, M.; Gilleard, J. S.; Cotton, J. A.
10.1101/2020.02.18.945246 — genomics — Posted on 2020-03-06
3472 Small molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's disease
Heller, G. T.; Aprile, F. A.; Michaels, T. C.; Limbocker, R.; Perni, M.; Ruggeri, F. S.; Mannini, B.; Lohr, T.; Bonomi, M.; Camilloni, C.; De Simone, A.; Felli, I. C.; Pierattelli, R.; Knowles, T. P.; Dobson, C. M.; Vendruscolo, M.
10.1101/729392 — biophysics — Posted on 2020-03-06
3478 Naught all zeros in sequence count data are the same
Silverman, J. D.; Roche, K.; Mukherjee, S.; David, L. A.
10.1101/477794 — bioinformatics — Posted on 2020-03-06
3479 Identification of novel glycosylation events on human serum-derived Factor IX
Pegg, C. L.; Zacchi, L. F.; Roche Recinos, D.; Howard, C. B.; Schulz, B. L.
10.1101/567941 — biochemistry — Posted on 2020-03-06
3481 Undinarchaeota illuminate the evolution of DPANN archaea
Dombrowski, N.; Williams, T. A.; Sun, J.; Woodcroft, B. J.; Lee, J.-H.; Minh, B. Q.; Rinke, C.; Spang, A.
10.1101/2020.03.05.976373 — evolutionary biology — Posted on 2020-03-05
3486 Epizootic of highly pathogenic H7N3 Avian Influenza in an ecologic reserve in Mexico.
Valdez-Gomez, H. E.; Navarro-Lopez, R.; Solis-Hernandez, M.; Marquez-Ruiz, M. A.; Rosas-Tellez, A.; Guichard-Romero, C. A.; Cartas-Heredia, G. d. J.; Morales-Espinosa, R.; Afonso, C. L.
10.1101/2020.03.05.978502 — pathology — Posted on 2020-03-05
3487 Essential roles for deubiquitination in Leishmania life cycle progression
Damianou, A.; Burge, R. J.; Catta-Preta, C.; Geoghegan, V.; Nievas, Y. R.; Newling, K.; Brown, E.; Burchmore, R.; Rodenko, B.; Mottram, J. C.
10.1101/2020.03.05.978528 — microbiology — Posted on 2020-03-05
3488 Global Profiling of 2-hydroxyisobutyrylome in Common Wheat
Zhang, N.; Zhang, L.; Li, L.; Geng, J.; Zhao, L.; Ren, Y.; Dong, Z.; Chen, F.
10.1101/2020.03.05.978155 — plant biology — Posted on 2020-03-05
3492 Isoform specificity in the mouse primary motor cortex
Booeshaghi, A. S.; Yao, Z.; Velthoven, C. v.; Smith, K.; Tasic, B.; Zeng, H.; Pachter, L.
10.1101/2020.03.05.977991 — neuroscience — Posted on 2020-03-05
3493 m6A RNA methylation regulates promoter proximal pausing of RNA Polymerase II
Akhtar, J.; Renaud, Y.; Albrecht, S.; Ghavi-Helm, Y.; Roignant, J.-Y.; Silies, M.; Junion, G.
10.1101/2020.03.05.978163 — molecular biology — Posted on 2020-03-05
3500 A missense in HSF2BP causing Primary Ovarian Insufficiency affects meiotic recombination by its novel interactor C19ORF57/MIDAP
Felipe-Medina, N.; Caburet, S.; Sanchez-Saez, F.; Codezo, Y. B.; de Rooij, D. G.; Gomez-H, L.; Garcia-Valiente, R.; Todeschini, A. L.; Duque, P.; Shalev, S.; Sanchez-Martin, M. A.; Llano, E.; Veitia, R.; Pendas, A. M.
10.1101/2020.03.05.978007 — genetics — Posted on 2020-03-05
3510 Symmetrically substituted dichlorophenes inhibit N-acyl-phosphatidylethanolamine phospholipase D
Aggarwal, G.; Zarrow, J. E.; Mashhadi, Z.; Flynn, C. R.; Vinson, P.; Weaver, C. D.; Davies, S. S.
10.1101/2020.03.05.979567 — biochemistry — Posted on 2020-03-05
3512 Implementation of a pre- and in-scan system to minimize head motion in pediatric participants undergoing fMRI scans
Horien, C.; Fontenelle, S.; Joseph, K.; Powell, N.; Nutor, C.; Fortes, D.; Butler, M.; Powell, K.; Macris, D.; Lee, K.; McPartland, J. C.; Volkmar, F. R.; Scheinost, D.; Chawarska, K.; Constable, R. T.
10.1101/2020.03.04.975417 — neuroscience — Posted on 2020-03-05
3515 Interrupting reactivation of immunological memory reprograms allergy and averts anaphylaxis
Bruton, K.; Spill, P.; Vohra, S.; Baribeau, O.; Manzoor, S.; Gadkar, S.; Davidson, M.; Walker, T. D.; Ellenbogen, Y.; Florescu, A.; Wen, J.; Chu, D. K.; Waserman, S.; Jimenez-Saiz, R.; Epelman, S.; Robbins, C.; Jordana, M.
10.1101/2020.03.04.975706 — immunology — Posted on 2020-03-05
3516 Systematic prioritization of candidate genes in disease loci identifies TRAFD1 as a master regulator of IFNγ signalling in celiac disease
van der Graaf, A.; Zorro, M.; Claringbould, A.; Vosa, U.; Aguirre-Gamboa, R.; Li, C.; Mooiweer, J.; Ricano-Ponce, I.; Borek, Z.; Koning, F.; Kooy-Winkelaar, Y.; Sollid, L.; Wang Qiao, S.; BIOS Consortium, ; Kumar, V.; Li, Y.; Franke, L.; Withoff, S.; Wijmenga, C.; Sanna, S.; Jonkers, I.
10.1101/2020.03.04.973487 — genetics — Posted on 2020-03-05
3517 Learning from local to global - an efficient distributed algorithm for modeling time-to-event data
Duan, R.; Luo, C.; Schuemie, M. H.; Tong, J.; Liang, J. C.; Chang, H. H.; Boland, M. R.; Bian, J.; Xu, H.; Holmes, J. H.; Forrest, C. B.; Morton, S. C.; Berlin, J. A.; Moore, J. H.; Mahoney, K. B.; Chen, Y.
10.1101/2020.03.04.977298 — bioinformatics — Posted on 2020-03-05
3518 Converting networks to predictive logic models from perturbation signalling data with CellNOpt
Gjerga, E.; Trairatphisan, P.; Gabor, A.; Koch, H.; Chevalier, C.; Ceccarelli, F.; Dugourd, A.; Mitsos, A.; Saez-Rodriguez, J.
10.1101/2020.03.04.976852 — bioinformatics — Posted on 2020-03-05
3519 Evolution of a plant gene cluster in Solanaceae and emergence of metabolic diversity
Fan, P.; Wang, P.; Lou, Y.-R.; Leong, B. J.; Moore, B. J.; Schenck, C. A.; Combs, R.; Cao, P.; Brandizzi, F.; Shiu, S.-H.; Last, R. L.
10.1101/2020.03.04.977231 — plant biology — Posted on 2020-03-05
3523 A TAL effector-like protein of symbiotic Mycetohabitans increases stress tolerance and alters the transcriptome of the fungal host Rhizopus microsporus
Carter, M. E.; Carpenter, S. C. D.; Dubrow, Z. E.; Sabol, M. R.; Rinaldi, F. C.; Lastovetsky, O. A.; Mondo, S. J.; Pawlowska, T. E.; Bogdanove, A. J.
10.1101/2020.03.04.968529 — microbiology — Posted on 2020-03-05
3524 Bacteroides thetaiotaomicron-infecting bacteriophage isolates inform sequence-based host range prediction
Hryckowian, A. J.; Merrill, B. D.; Porter, N. T.; Van Treuren, W.; Nelson, E. J.; Garlena, R. A.; Russell, D. A.; Martens, E. C.; Sonnenburg, J. L.
10.1101/2020.03.04.977157 — microbiology — Posted on 2020-03-05
3531 Trends in animal model preference for preclinical drug testing for type-2 diabetes and future directions
Franco, N. H.; Miranda, S. F. B.; Kovacs, N.; Nagy, A.; Akinsolu, F. T.; Olsson, I. A. S.; Varga, O.
10.1101/2020.03.03.973230 — pharmacology and toxicology — Posted on 2020-03-05
3533 Creation of an Open Science Dataset from PREVENT-AD, a Longitudinal Cohort Study of Pre-symptomatic Alzheimer's Disease.
Tremblay-Mercier, J.; Madjar, C.; Das, S.; Dyke, S. O. M.; Etienne, P.; Lafaille-Magnan, M.-E.; Bellec, P.; Collins, D. L.; Rajah, M. N.; Bohbot, V. D.; Leoutsakos, J.-M.; Iturria-Medina, Y.; Kat, J.; Hoge, R. D.; Gauthier, S.; Chakravarty, M. M.; Poline, J.-B.; Rosa-Neto, P.; Villeneuve, S.; Evans, A. C.; Poirier, J.; Breitner, J. C. S.; the PREVENT-AD Research Group,
10.1101/2020.03.04.976670 — neuroscience — Posted on 2020-03-05
3535 Nascent transcript folding plays a major role in determining RNA polymerase elongation rates
Turowski, T. W.; Petfalski, E.; Goddard, B. D.; French, S. L.; Helwak, A.; Tollervey, D.
10.1101/2020.03.05.969709 — molecular biology — Posted on 2020-03-05
3537 Bacteroides uniformis enhances endurance exercise performance through gluconeogenesis
Morita, H.; Kano, C.; Ishii, C.; Kagata, N.; Ishikawa, T.; Uchiyama, Y.; Hara, S.; Nakamura, T.; Fukuda, S.
10.1101/2020.03.04.975730 — microbiology — Posted on 2020-03-05
3540 Public broadly neutralizing antibodies against hepatitis B virus in individuals with elite serologic activity
Wang, Q.; Michailidis, E.; Yu, Y.; Wang, Z.; Hurley, A. M.; Oren, D. A.; Mayer, C. T.; Gazumyan, A.; Liu, Z.; Zhou, Y.; Schoofs, T.; Yao, K.-h.; Nieke, J.; Wu, J.; Jiang, Q.; Zou, C.; Kabbani, M.; Quirk, C.; Oliveira, T.; Chhosphel, K.; Zhang, Q.; Schneider, W. M.; Jahan, C.; Ying, T.; Horowitz, J.; Caskey, M.; Jankovic, M.; Robbiani, D. F.; Wen, Y.; de Jong, Y. P.; Rice, C. M.; Nussenzweig, M. C.
10.1101/2020.03.04.976159 — immunology — Posted on 2020-03-05
3544 MosaicBase: A Knowledgebase of Postzygotic Mosaic Variants in Noncancer Diseases and Asymptomatic Human Individuals
Yang, X.; Yang, C.; Zheng, X.; Xiong, L.; Tao, Y.; Wang, M.; Ye, A. Y.; Wu, Q.; Dou, Y.; Luo, J.; Wei, L.; Huang, A. Y.
10.1101/2020.03.04.976803 — bioinformatics — Posted on 2020-03-05
3547 Co-occurrence, habitat use and activity pattern of carnivore species in a coastal area of Argentina
Caruso, N. C.; Luengos Vidal, E. M.; Manfredi, M. C.; Araujo, M. S.; Lucherini, M.; Casanave, E. B.
10.1101/2020.03.04.976415 — zoology — Posted on 2020-03-05
3548 The landscape of molecular chaperones across human tissues reveals a layered architecture of core and variable chaperones
Shemesh, N.; Jubran, J.; Abu-Qarn, M.; Simonovky, E.; Basha, O.; Hekselman, I.; Dror, S.; Vinogradov, E.; Carra, S.; Ben-Zvi, A.; Yeger-Lotem, E.
10.1101/2020.03.04.976720 — systems biology — Posted on 2020-03-05
3552 The m6A reader Ythdf restricts axonal growth in Drosophila through target selection modulation of the Fragile X mental retardation protein
Soldano, A.; Worpenberg, L.; Paolantoni, C.; Longhi, S.; Mulorz, M. M.; Lence, T.; Wessels, H.-H.; Aiello, G.; Notarangelo, M.; Sutandy, F. R.; Scheibe, M.; Edupuganti, R. R.; Busch, A.; Mockel, M. M.; Vermeulen, M.; Butter, F.; Konig, J.; Ohler, U.; Dieterich, C.; Quattrone, A.; Roignant, J.-Y.
10.1101/2020.03.04.976886 — molecular biology — Posted on 2020-03-05
3557 Metagenomic data reveal diverse fungal and algal communities associated with the lichen symbiosis
Smith, H.; dal Grande, F.; Muggia, L.; Keuler, R.; Divakar, P. K.; Grewe, F.; Schmitt, I.; Lumbsch, T.; Leavitt, S.
10.1101/2020.03.04.966853 — ecology — Posted on 2020-03-05
3558 Predicting the Environmental Suitability and Population at Risk of Podoconiosis in Africa
Deribe, K.; Simpson, H.; Pullan, R. L.; Jean Bosco, M.; Wanji, S.; Weaver, N. D.; Murray, C. J. L.; Newport, M. J.; Hay, S. I.; Davey, G.; Cano, J.
10.1101/2020.03.04.977827 — ecology — Posted on 2020-03-05
3559 Lipid membrane templated misfolding and self-assembly of intrinsically disordered tau protein
Chi, E. Y.; Majewski, J.; Jones, E.; Vander Zanden, C.; Biernat, J.; Mandelkow, E.
10.1101/2020.03.04.977421 — biophysics — Posted on 2020-03-05
3560 Pairwise and Higher-Order Epistatic Interactions Have a Significant Impact on Bronchodilator Drug Response in African American Youth with Asthma
Magana, J.; Contreras, M.; Keys, K.; Risse-Adams, O.; Goddard, P. C.; Zeiger, A. M.; Mak, A. C. Y.; Elhawary, J. R.; Samedy-Bates, L.-A.; Lee, E.; Thakur, N.; Hu, D.; Eng, C.; Salazar, S.; Huntsman, S.; Hu, T.; Burchard, E. G.; White, M. J.
10.1101/2020.03.04.977066 — bioinformatics — Posted on 2020-03-05
3564 Genetic elucidation of complex biochemical traits mediating maize innate immunity
Ding, Y.; Weckwerth, P. R.; Poretsky, E.; Murphy, K. M.; Sims, J.; Saldivar, E.; Christensen, S. A.; Char, S. N.; Yang, B.; Tong, A.-d.; Shen, Z.; Kremling, K.; Buckler, E. S.; Kono, T. J. Y.; Nelson, D. R.; Bohlmann, J.; Bakker, M. G.; Vaughan, M. M.; Khalil, A. S.; Betsiashvili, M.; Briggs, S.; Zerbe, P.; Schmelz, E. A.; Huffaker, A.
10.1101/2020.03.04.977355 — plant biology — Posted on 2020-03-05
3567 An Integrated Systems Biology Approach Identifies the Proteasome as a Critical Host Machinery for ZIKV and DENV Replication
Song, G.; Lee, E. M.; Pan, J.; Xu, M.; Rho, H.-S.; Cheng, Y.; Whitt, N.; Yang, S.; Kouznetsova, J.; Klumpp-Thomas, C.; Michael, S.; Moore, C.; Yoon, K.-J.; Christian, K.; Simeonov, A.; Huang, W.; Xia, M.; Huang, R.; Lal-Nag, M.; Tang, H.; Zheng, W.; Qian, J.; Song, H.; Ming, G.-l.; Zhu, H.
10.1101/2020.03.04.976548 — microbiology — Posted on 2020-03-05
3568 Competitive mapping allows to identify and exclude human DNA contamination in ancient faunal genomic datasets
Feuerborn, T. R.; Palkopoulou, E.; van der Valk, T.; von Seth, J.; Munters, A.; Pecnerova, P.; Dehasque, M.; Urena, I.; Ersmark, E.; Lagerholm, V. K.; Krzewinska, M.; Rodriguez-Varela, R.; Götherström, A.; Dalen, L.; Diez-del-Molino, D.
10.1101/2020.03.05.974907 — genomics — Posted on 2020-03-05
3569 The contribution of de novo tandem repeat mutations to autism spectrum disorders
Mitra, I.; Mousavi, N.; Ma, N.; Lamkin, M.; Yanicky, R.; Shleizer-Burko, S.; Gymrek, M.
10.1101/2020.03.04.974170 — genomics — Posted on 2020-03-05
3570 Alt-RPL36 downregulates the PI3K-AKT-mTOR signaling pathway by interacting with TMEM24
Cao, X.; Khitun, A.; Na, Z.; Phoodokmai, T.; Sappakhaw, K.; Olatunji, E.; Uttamapinant, C.; Slavoff, S. A.
10.1101/2020.03.04.977314 — genomics — Posted on 2020-03-05
3572 Risk of preeclampsia in patients with genetic predisposition to common medical conditions: a case-control study
Gray, K. J.; Kovacheva, V. P.; Mirzakhani, H.; Bjonnes, A. C.; Almoguera, B.; Wilson, M. L.; Ingles, S. A.; Lockwood, C. J.; Hakonarson, H.; McElrath, T. F.; Murray, J. C.; Norwitz, E. R.; Karumanchi, S. A.; Bateman, B. T.; Keating, B. J.; Saxena, R.
10.1101/2020.03.04.976472 — genetics — Posted on 2020-03-05
3577 Superabsorbent crosslinked bacterial cellulose biomaterials for chronic wound dressings
Ciecholewska-Jusko, D.; Zywicka, A.; Junka, A.; Drozd, R.; Sobolewski, P.; Migdal, P.; Kowalska, U.; Toporkiewicz, M.; Fijalkowski, K.
10.1101/2020.03.04.975003 — bioengineering — Posted on 2020-03-05
3585 A transcriptomic atlas of the mouse cerebellum reveals regional specializations and novel cell types
Kozareva, V.; Martin, C.; Osorno, T.; Rudolph, S.; Guo, C.; Vanderburg, C.; Nadaf, N. M.; Regev, A.; Regehr, W.; Macosko, E.
10.1101/2020.03.04.976407 — genomics — Posted on 2020-03-05
3589 An antimicrobial origin of targeting peptides to endosymbiotic organelles
Garrido, C. O.; Caspari, O. D.; Choquet, Y.; Wollman, F.-A.; Lafontaine, I.
10.1101/2020.03.04.974964 — evolutionary biology — Posted on 2020-03-05
3593 Great Expectations: A Critical Review of and Recommendations for the study of Reward Processing as a Cause and Predictor of Depression
Nielson, D. M.; Keren, H.; O'Callaghan, G.; Jackson, S. M.; Douka, I.; Zheng, C. Y.; Vidal-Ribas Belil, P.; Pornpattananangkul, N.; Camp, C. C.; Gorham, L. S.; Wei, C.; Kirwan, S.; Stringaris, A.
10.1101/2020.03.04.975136 — neuroscience — Posted on 2020-03-05
3594 Anti-inflammatory role of GM1 and modulatory effects of gangliosides on microglia functions
Galleguillos, D.; Wang, Q.; Steinberg, N.; Shrivastava, G.; Dhami, K.; Rubinstein, K.; Giuliani, F.; Churchward, M.; Power, C.; Todd, K.; Sipione, S.
10.1101/2020.03.04.975862 — neuroscience — Posted on 2020-03-05
3598 Molecular Ecology of Coral Reef Microorganisms in the Western Indian Ocean coast of Kenya
Wambua, S.; Gourle, H.; de Villiers, E.; Karlsson, O. E.; Wambiji, N.; Macdonald, A.; Bongcam-Rudloff, E.; de Villiers, S.
10.1101/2020.03.04.976431 — ecology — Posted on 2020-03-05
3600 Expanding the Coverage of the Metabolic Landscape in Cultivated Rice with Integrated Computational Approaches
Li, X.; Zhou, H.; Xiao, N.; Wu, X.; Shan, Y.; Chen, L.; Wang, C.; Wang, Z.; Huang, J.; Li, A.; Li, X.
10.1101/2020.03.04.976266 — bioinformatics — Posted on 2020-03-05
3602 Population Stratification at the Phenotypic Variance level and Implication for the Analysis of Whole Genome Sequencing Data from Multiple Studies
Sofer, T.; Zheng, X.; Laurie, C. A.; Gogarten, S. M.; Brody, J. A.; Conomos, M. P.; Bis, J. C.; Thornton, T. A.; Szpiro, A.; O'Connell, J. R.; Lange, E. M.; Gao, Y.; Cupples, L. A.; Psaty, B. M.; Trans-Omics for Precision Medicine (TOPMed) Consortium, ; Rice, K. M.
10.1101/2020.03.03.973420 — genetics — Posted on 2020-03-05
3608 Structure-function analysis of Arabidopsis TOPLESS reveals conservation of repression mechanisms across eukaryotes
Leydon, A. R.; Wang, W.; Juarez-Solis, S.; Zemke, J. E.; Zahler, M. L.; Zheng, N.; Nemhauser, J. L.
10.1101/2020.03.04.976134 — plant biology — Posted on 2020-03-05
3609 Marine snow as a habitat for microbial mercury methylators in the Baltic Sea
Capo, E.; Bravo, A. G.; Soerensen, A. L.; Bertilsson, S.; Pinhassi, J.; Feng, C.; Andersson, A. F.; Buck, M.; Bjorn, E. A.
10.1101/2020.03.04.975987 — microbiology — Posted on 2020-03-05
3610 Chromosomal-level reference genome of the incense tree Aquilaria sinensis
Nong, W.; Law, S. T. S.; Wong, A.; Baril, T.; Swale, T.; Chu, L. M.; Hayward, A.; Lau, D. T. W.; Hui, J. H. L.
10.1101/2020.03.03.972679 — genomics — Posted on 2020-03-05
3612 AIDeveloper: deep learning image classification in life science and beyond
Krater, M.; Abuhattum, S.; Soteriou, D.; Jacobi, A.; Kruger, T.; Guck, J.; Herbig, M.
10.1101/2020.03.03.975250 — bioinformatics — Posted on 2020-03-05
3614 GmVTL1 is an iron transporter on the symbiosome membrane of soybean with an important role in nitrogen fixation.
Brear, E. M.; Bedon, f.; Gavrin, A.; Kryvoruchko, I. S.; Torres-Jerez, I.; Udvardi, M.; Day, D. A.; Smith, P. M. C.
10.1101/2020.03.03.975805 — plant biology — Posted on 2020-03-05
3616 A novel bat coronavirus reveals natural insertions at the S1/S2 cleavage site of the Spike protein and a possible recombinant origin of HCoV-19
Zhou, H.; Chen, X.; Hu, T.; Li, J.; Song, H.; Liu, Y.; Wang, P.; Liu, D.; Yang, J.; Holmes, E. C.; Hughes, A. C.; Bi, Y.; Shi, W.
10.1101/2020.03.02.974139 — microbiology — Posted on 2020-03-05
3617 Non-CG methylation is superior to CG methylation in genome regulation
Domb, K.; Katz, A.; Yaari, R.; Kaisler, E.; Nguyen, V. H.; Hong, U. V. T.; Griess, O.; Gitin Heskiau, K.; Ohad, N.; Zemach, A.
10.1101/2020.03.04.971267 — genomics — Posted on 2020-03-05
3624 Developmental differentiation in a cytoplasm-dwelling obligate intracellular bacterium
Giengkam, S.; Wongsantichon, J.; Atwal, S.; Jaiyen, Y.; Goh, W. I.; Wright, G.; Chung, T.; Huh, H.; Lee, S.; Sobota, R.; Salje, J.
10.1101/2020.03.03.975011 — microbiology — Posted on 2020-03-05
3627 ICELLNET: a transcriptome-based framework to dissect intercellular communication
Noël, F.; Massenet-Regad, L.; Carmi-Levy, I.; Cappuccio, A.; Grandclaudon, M.; Trichot, C.; Kieffer, Y.; Mechta-Grigoriou, F.; Soumelis, V.
10.1101/2020.03.05.976878 — systems biology — Posted on 2020-03-05
3628 ppGpp influences protein protection, growth and photosynthesis in Phaeodactylum tricornutum
Avilan, L.; Lebrun, R.; Puppo, C.; Citerne, S.; Cuine, S.; Li-Beisson, Y.; Menand, B.; Field, B.; Gontero, B.
10.1101/2020.03.05.978130 — plant biology — Posted on 2020-03-05
3630 Age-related differences in auditory cortex activity during spoken word recognition
Rogers, C. S.; Jones, M. S.; McConkey, S.; Spehar, B.; Van Engen, K. J.; Sommers, M. S.; Peelle, J. E.
10.1101/2020.03.05.977306 — neuroscience — Posted on 2020-03-05
3631 Rerouting of ribosomal proteins into splicing in plant organelles
Wang, C.; Fourdin, R.; Quadrado, M.; Dargel-Graffin, C.; Tolleter, D.; Macherel, D.; Mireau, H.
10.1101/2020.03.03.974766 — molecular biology — Posted on 2020-03-05
3632 Rapid metagenomic characterization of a case of imported COVID-19 in Cambodia
Manning, J. E.; Bohl, J. A.; Lay, S.; Chea, S.; Ly, S.; Sengdoeurn, Y.; Heng, S.; Vuthy, C.; Kalantar, K.; Ahyong, V.; Tan, M.; Sheu, J.; Tato, C. M.; DeRisi, J.; Baril, L.; Dussart, P.; Duong, V.; Karlsson, E. A.
10.1101/2020.03.02.968818 — microbiology — Posted on 2020-03-05
3637 Myocardial damage induced by a single high dose of isoproterenol in C57BL/6J mice triggers a persistent adaptive immune response against the heart.
Forte, E.; Panahi, M.; Ng, F. S.; Boyle, J. J.; Branca, J.; Bedard, O.; Hasham, M. G.; Benson, L.; Harding, S. E.; Rosenthal, N.; Sattler, S.
10.1101/2020.02.27.962696 — immunology — Posted on 2020-03-05
3638 Mucosal delivery of a multistage subunit vaccine promotes development of lung-resident memory T cells and affords interleukin-17-dependant protection against pulmonary tuberculosis
Counoupas, C.; Ferrell, K.; Ashhurst, A.; Bhattacharyya, N. D.; Nagalingam, G.; Feng, C. G.; Petrovsky, N.; Britton, W. J.; Triccas, J. A.
10.1101/2020.02.25.964312 — immunology — Posted on 2020-03-05
3639 The architecture of brain co-expression reveals the brain-wide basis of disease susceptibility
Hartl, C. L.; Ramaswami, G.; Pembroke, W.; Saha, A.; Parsana, P.; Muller, S.; Pintacuda, G.; Lage, K.; Battle, A.; Geschwind, D. H.
10.1101/2020.03.05.965749 — genetics — Posted on 2020-03-05
3641 The gliopeptide ODN, a ligand for the benzodiazepine site of GABAA receptors, boosts functional recovery after stroke
Lamtahri, R.; Hazime, M.; Gowing, E. K.; Nagaraja, R. Y.; Maucotel, J.; Quilichini, P.; Lehongre, K.; Lefranc, B.; Gach-Janczak, K.; Marcher, A.-B.; Mandrup, S.; Vaudry, D.; Clarkson, A.; Leprince, J.; Chuquet, J.
10.1101/2020.03.05.977934 — neuroscience — Posted on 2020-03-05
3642 Aberrant Sensory Encoding in Patients with Autism
Noel, J.-P.; Zhang, L.-Q.; Stocker, A.; Angelaki, D.
10.1101/2020.03.04.976191 — neuroscience — Posted on 2020-03-05
3648 Early maturational emergence of adult-like emotional reactivity and anxiety after brief exposure to an obesogenic diet
Vega-Torres, J. D.; Azadian, M.; Rios-Orsini, R.; Reyes-Rivera, A. L.; Ontiveros-Angel, P.; Figueroa, J. D.
10.1101/2020.03.03.975789 — neuroscience — Posted on 2020-03-05
3649 Exifone is a Potent HDAC1 Activator with Neuroprotective Activity in Human Neuronal Models of Neurodegeneration
Patnaik, D.; Pao, P.-C.; Zhao, W.-N.; Silva, M. C.; Hylton, N. K.; Chindavong, P. S.; Pan, L.; Tsai, L.-H.; Haggarty, S. J.
10.1101/2020.03.02.973636 — biochemistry — Posted on 2020-03-05
3651 A neural code of egocentric spatial information in human medial temporal lobe
Kunz, L.; Brandt, A.; Reinacher, P. C.; Staresina, B. P.; Reifenstein, E. T.; Weidemann, C. T.; Herweg, N. A.; Tsitsiklis, M.; Kempter, R.; Kahana, M. J.; Schulze-Bonhage, A.; Jacobs, J.
10.1101/2020.03.03.973131 — neuroscience — Posted on 2020-03-05
3653 Analysis of structural brain asymmetries in Attention-Deficit/Hyperactivity Disorder in 39 datasets
Postema, M. C.; Hoogman, M.; ENIGMA ADHD Working Group, ; Glahn, D. C.; Jahanshad, N.; Medland, S.; Thompson, P. M.; Fisher, S. E.; Franke, B.; Francks, C.
10.1101/2020.03.03.974758 — neuroscience — Posted on 2020-03-05
3655 The Effect of a Virtual No-Step Zone on Balance Control in Walking
Fettrow, T.; DiBianca, S.; Vanderlinde dos Santos, F.; Reimann, H.; Jeka, J.
10.1101/2020.02.28.970152 — neuroscience — Posted on 2020-03-05
3659 Extended amygdala-parabrachial circuits alter threat assessment to regulate feeding
Bhatti, D. L.; Luskin, A. T.; Pedersen, C. E.; Mulvey, B.; Oden-Brunson, H.; Kimbell, K.; Sawyer, A.; Gereau, R. W.; Dougherty, J. D.; Bruchas, M. R.
10.1101/2020.03.03.975193 — neuroscience — Posted on 2020-03-05
3661 Children Developing Celiac Disease Have a Distinct and Proinflammatory Gut Microbiota in the First 5 Years of Life
Huang, Q.; Yang, Y.; Tolstikov, V.; Kiebish, M. A.; Ludvigsson, J. F.; Palm, N. W.; Ludvigsson, J.; ALTINDIS, E.
10.1101/2020.02.29.971242 — microbiology — Posted on 2020-03-05
3662 Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA
Wang, K.; Lin, R.-Z.; Hong, X.; Ng, A.; Lee, C.-N.; Neumeyer, J.; Wang, G.; Wang, X.; Ma, M.; Pu, W.; Church, G.; Melero-Martin, J.
10.1101/2020.03.02.973289 — cell biology — Posted on 2020-03-05
3663 Defining Strawberry Uniformity using 3D Imaging and Genetic Mapping
Li, B.; Cockerton, H. M.; Johnson, A. W.; Karlstrom, A.; stavridou, E.; Deakin, G.; Harrison, R. J.
10.1101/2020.03.01.972190 — bioinformatics — Posted on 2020-03-05
3664 Phosphorylation by Aurora B kinase regulates caspase-2 activity and function
Kumar, S.; Lim, Y.; De Bellis, D.; Sandow, J. J.; Capalbo, L.; D'Avino, P. P.; Murphy, J. M.; Webb, A. I.; Dorstyn, L.
10.1101/2020.03.05.978056 — cell biology — Posted on 2020-03-05
3665 CYP154C5 regioselectivity in steroid hydroxylation explored by substrate and protein engineering
Bracco, P.; Wijma, H. J.; Nicolai, B.; Rodriguez Buitrago, J. A.; Kluenemann, T.; Vila, A.; Schrepfer, P.; Blankenfeldt, W.; Janssen, D. B.; Schallmey, A.
10.1101/2020.03.04.972729 — biochemistry — Posted on 2020-03-05
3667 Mechanistic Determinants of Slow Axonal Transport and Presynaptic Targeting of Clathrin Packets
Ganguly, A.; Wernert, F.; Phan, S.; BOASSA, D.; Das, U.; Sharma, R.; Caillol, G.; Han, X.; Yates, J. R.; Ellisman, M.; Leterrier, C.; Roy, S.
10.1101/2020.02.20.958140 — neuroscience — Posted on 2020-03-05
3668 A novel Ataxin-3 knock-in mouse model mimics the human SCA3 disease phenotype including neuropathological, behavioral, and transcriptional abnormalities
Haas, E.; Incebacak, R. D.; Hentrich, T.; Maringer, Y.; Schmidt, T.; Zimmermann, F.; Casadei, N.; Mills, J. D.; Aronica, E.; Riess, O. H.; Schulze-Hentrich, J. M.; Huebener-Schmid, J.
10.1101/2020.02.28.968024 — neuroscience — Posted on 2020-03-05
3672 Adipose-tissue derived signals control bone remodelling.
Fu, H.; Madel, M.-B.; Pierroz, D.; Schiffrin, M.; Winkler, C.; Wilson, A.; Pochon, C.; Toffoli, B.; Jouzeau, J.-Y.; Gilardi, F.; Ferrari, S.; Bonnet, N.; BLIN-WAKKACH, C.; Desvergne, B.; MOULIN, D.
10.1101/2020.03.02.972711 — cell biology — Posted on 2020-03-05
3675 Plagues of Desert Locust: No invasion risk to China
Wang, Y.-P.; Wu, M.-F.; Lin, P.-J.; Wang, Y.; Chen, A.-D.; Jiang, Y.-Y.; Zhai, B.-P.; Chapman, J. W.; Hu, G.
10.1101/2020.03.03.973834 — ecology — Posted on 2020-03-05
3676 Sox2-dependent maintenance of mouse oligodendroglioma involves the Sox2-mediated downregulation of Cdkn2b, Ebf1, Zfp423 and Hey2
Barone, C.; Buccarelli, M.; Alessandrini, F.; Pagin, M.; Rigoldi, L.; Sambruni, I.; Favaro, R.; Ottolenghi, S.; Pallini, R.; Ricci-Vitiani, L.; Malatesta, P.; Nicolis, S. K.
10.1101/2020.03.04.976811 — cancer biology — Posted on 2020-03-05
3680 A lineage-tracing tool to map the fate of post-hypoxic H1299 NSCLC tumour cells
Vermeer, J. A. F.; Ient, J.; Markelc, B.; Kaeppler, J.; Barbeau, L. M. O.; Groot, A. J.; Muschel, R. J.; Vooijs, M. A.
10.1101/2020.03.03.974857 — cancer biology — Posted on 2020-03-05
3681 A unifying model to predict variable drug response for personalised medicine
van der Lee, M.; Allard, W. G.; Vossen, R. H. A. M.; Baak-Pablo, R. F.; Menafra, R.; Deiman, B. A. L. M.; Deenen, M. J.; Neven, P.; Johansson, I.; Gastaldello, S.; Ingelman-Sundberg, M.; Guchelaar, H.-J.; Swen, J. J.; Anvar, S. Y.
10.1101/2020.03.02.967554 — pharmacology and toxicology — Posted on 2020-03-05
3682 TGFβ Suppresses Type 2 Immunity to Cancer
Liu, M.; Kuo, F.; Capistrano, K.; Kang, D.; Nixon, B.; Shi, W.; Chou, C.; Do, M.; Li, S.; Stamatiades, E.; Chen, Y.; Hsieh, J.; Hakimi, A.; Taniuchi, I.; Chan, T.; Li, M.
10.1101/2020.03.04.977629 — immunology — Posted on 2020-03-05
3685 Viral Architecture of SARS-CoV-2 with Post-Fusion Spike Revealed by Cryo-EM
Liu, C.; Yang, Y.; Gao, Y.; Shen, C.; Ju, B.; Liu, C.; Tang, X.; Wei, J.; Ma, X.; Liu, W.; Xu, S.; Liu, Y.; Yuan, J.; Wu, J.; Liu, Z.; Zhang, Z.; Wang, P.; Liu, L.
10.1101/2020.03.02.972927 — microbiology — Posted on 2020-03-05
3686 Nrf2 represses ER stress-related ferroptosis in renal carcinoma cells via HO-1
Shen, Y.; Hu, Z.; Tian, J.; Gan, J.; Ke, C.; Yang, C.; Zeng, X.; Shen, G.
10.1101/2020.03.04.977769 — cancer biology — Posted on 2020-03-05
3687 Low expression of ANT1 confers oncogenic properties to rhabdomyosarcoma tumor cells via modulating metabolism and death pathways.
Vial, J.; Huchede, P.; Fagault, S.; Basset, F.; Rossi, M.; Geoffray, J.; Bisaccia, J.; Creveaux, M.; Neves, D.; Fauvelle, F.; Castets, P.; Carre, M.; Weber, K.; Castets, M.
10.1101/2020.03.03.973719 — cancer biology — Posted on 2020-03-05
3688 Histidine-Triad Hydrolases Provide Resistance to Peptide-Nucleotide Antibiotics
Yagmurov, E.; Tsibulskaya, D.; Livenskyi, A.; Serebryakova, M.; Wolf, Y. I.; Borukhov, S.; Severinov, K. V.; Dubiley, S.
10.1101/2020.03.04.977132 — biochemistry — Posted on 2020-03-05
3689 Genome-wide alterations of uracil distribution patterns in human DNA upon chemotherapeutic treatments
Palinkas, H. L.; Bekesi, A.; Rona, G.; Pongor, L.; Tihanyi, G.; Holub, E.; Poti, A.; Gemma, C.; Ali, S.; Morten, M. J.; Rothenberg, E.; Pagano, M.; Szuts, D.; Gyorffy, B.; Vertessy, B. G.
10.1101/2020.03.04.976977 — biochemistry — Posted on 2020-03-05
3690 Solanaceae specialized metabolism in a non-model plant: trichome acylinositol biosynthesis
Leong, B.; Hurney, S. M.; Fiesel, P. D.; Moghe, G. D.; Jones, A. D.; Last, R. L.
10.1101/2020.03.04.977181 — biochemistry — Posted on 2020-03-05
3691 Visual Biochemistry: modular microfluidics enables kinetic insight from time-resolved cryo-EM
Maeots, M.-E.; Lee, B.; Nans, A.; Jeong, S.-G.; Esfahani, M. M. N.; Smith, D. J.; Lee, C.-S.; Lee, S. S.; Peter, M.; Enchev, R. I.
10.1101/2020.03.04.972604 — biochemistry — Posted on 2020-03-05
3694 An In Vitro Vascularized Micro-Tumor Model of Human Colorectal Cancer Recapitulates In Vivo Drug Responses
Hachey, S. J.; Movsesyan, S.; Nguyen, Q. H.; Burton-Sojo, G.; Tankazyan, A.; Wu, J.; Hoang, T.; Hatch, M. M.; Zhao, D.; Celaya, E.; Gomez, S.; Chen, G. T.; Davis, R. T.; Nee, K.; Pervolarakis, N.; Lawson, D. A.; Kessenbrock, K.; Lee, A. P.; Waterman, M. L.; Hughes, C. C.
10.1101/2020.03.03.973891 — cancer biology — Posted on 2020-03-05
3696 Acoustofluidic Assembly of 3D Neurospheroids to Model Alzheimer's Disease
Cai, H.; Ao, Z.; Hu, L.; Moon, Y.; Wu, Z.; Lu, H.-C.; Kim, J.; Guo, F.
10.1101/2020.03.03.972299 — bioengineering — Posted on 2020-03-05
3698 The physical form of microbial ligands bypasses the need for dendritic cell migration to stimulate adaptive immunity
Borriello, F.; Spreafico, R.; Poli, V.; Chou, J.; Barrett, N.; Lacanfora, L.; Franco, M.; Marongiu, L.; Iwakura, Y.; Pucci, F.; Kruppa, M.; Ma, Z.; Williams, D.; Zanoni, I.
10.1101/2020.03.03.973727 — immunology — Posted on 2020-03-05
3700 LRP5 promotes adipose progenitor cell fitness and adipocyte insulin sensitivity
Loh, N. Y.; Vasan, S. K.; Verma, M.; Wesolowska-Andersen, A.; Neville, M. J.; Osmond, C.; Gregson, C. L.; Karpe, F. L.; Christodoulides, C.
10.1101/2020.03.04.976647 — cell biology — Posted on 2020-03-05
3702 An integrated transcriptomic and epigenomic atlas of mouse primary motor cortex cell types
Yao, Z.; Liu, H.; Xie, F.; Fischer, S.; Adkins, R. S.; Aldrige, A. I.; Ament, S. A.; Bartlett, A.; Behrens, M. M.; Van den Berge, K.; Bertagnolli, D.; Biancalani, T.; Booeshaghi, A. S.; Corrada Bravo, H.; Casper, T.; Colantuoni, C.; Crabtree, J.; Creasy, H.; Crichton, K.; Crow, M.; Dee, N.; Dougherty, E. L.; Doyle, W. I.; Dudoit, S.; Fang, R.; Felix, V.; Fong, O.; Giglio, M.; Goldy, J.; Hawrylycz, M.; Bezieux, H. R. d.; Herb, B. R.; Hertzano, R.; Hou, X.; Hu, Q.; Huang, Z. J.; Kancherla, J.; Kroll, M.; Lathia, K.; Li, Y. E.; Lucero, J. D.; Luo, C.; Mahurkar, A.; McMillen, D.; Nadaf, N. M.; Ner
10.1101/2020.02.29.970558 — neuroscience — Posted on 2020-03-05
3705 Chemokine receptor 2-targeted molecular imaging in pulmonary fibrosis
Brody, S. L.; Gunsten, S. P.; Luehmann, H. P.; Sultan, D. H.; Hoelscher, M.; Heo, G. S.; Pan, J.; Koenitzer, J. R.; Lee, E. C.; Huang, T.; Mpoy, C.; Guo, S.; Laforest, R.; Salter, A.; Russell, T. D.; Shifren, A.; Combadiere, C.; Lavine, K. J.; Kreisel, D.; Humphreys, B. D.; Rogers, B. E.; Grierada, D. S.; Byers, D. E.; Gropler, R. J.; Chen, D. L.; Atkinson, J. J.; Liu, Y.
10.1101/2020.03.04.960179 — cell biology — Posted on 2020-03-05
3707 Caloric Restriction recovers impaired β-cell-β-cell coupling, calcium oscillation coordination and insulin secretion in prediabetic mice
do Amaral, M. E. C.; Kravets, V.; Dwulet, J. M.; Farnsworth, N. L.; Piscopio, R.; Schleicher, W. E.; Miranda, J. G.; Benninger, R. K.
10.1101/2020.03.03.975961 — physiology — Posted on 2020-03-05
3710 Multimodal mapping of neural activity and cerebral blood flow reveals long-lasting neurovascular dissociations after small-scale strokes
He, F.; Sullender, C. T.; Zhu, H.; Williamson, M. R.; Li, X.; Zhao, Z.; Jones, T. A.; Xie, C.; Dunn, A. K.; Luan, L.
10.1101/2020.03.04.977322 — neuroscience — Posted on 2020-03-05
3711 Recombinant Protein IGF1-24 Stimulates Rat Cardiomyocytes Proliferation and Repairs Myocardial Injury
WANG, X.; Fu, M.; Yi, Q.; Feng, J.; Liao, Y.; Xu, X.; Chen, Y.; Zhang, L.; Sun, H.; Liu, P.; Liang, Y.; Tang, l.
10.1101/2020.03.04.976522 — developmental biology — Posted on 2020-03-05
3712 C-Eci: A Cubic-Eci Combined Clearing Method For 3D Follicular Content Analysis In The Fish Ovary
Lesage, M.; Thomas, M.; Bugeon, J.; Branthonne, A.; Gay, S.; Cardona, E.; Bobe, J.; Thermes, V.
10.1101/2020.03.05.978189 — developmental biology — Posted on 2020-03-05
3715 Cardiac CapZ regulation during acute exercise
Laskary, A.; Townsend, L. K.; Wright, D. C.; Pyle, W. G.
10.1101/2020.03.03.975185 — physiology — Posted on 2020-03-05
3717 Structure and mechanism of a primate ferroportin
Ren, Z.; Gao, S.; Shen, J.; Wang, L.; Xu, Z.; Yu, Y.; Bachina, P.; Zhang, H.; Laganowsky, A.; Yan, N.; Zhou, M.; Pan, Y.
10.1101/2020.03.04.975748 — biochemistry — Posted on 2020-03-05
3718 STK32A is a dual-specificity AGC kinase with a preference for acidic substrates
Sorrell, F. J.; Miranda, F.; Abdul Azeez, K. R.; Chaikuad, A.; Kettenbach, A. N.; Gerber, S.; Knapp, S.; Ahmed, A. A.; Elkins, J.
10.1101/2020.03.04.976555 — biochemistry — Posted on 2020-03-05
3719 Proteomics Reveals Extracellular Matrix Injury in the Glomeruli and Tubulointerstitium of Kidney Allografts with Early Antibody-Mediated Rejection
Clotet-Freixas, S.; McEvoy, C. M.; Batruch, I.; Van, J.; Pastrello, C.; Kotlyar, M.; Arambewela, M.; Boshart, A.; Farkona, S.; Niu, Y.; Li, Y.; Famure, O.; Bozovic, A.; Kulasingam, V.; Chen, P.; Kim, J.; Chan, E.; Moshkelgosha, S.; Martinu, T.; Juvet, S.; Jurisica, I.; Chruscinski, A.; John, R.; Konvalinka, A.
10.1101/2020.03.03.975672 — molecular biology — Posted on 2020-03-05
3720 Network potential identifies therapeutic miRNA cocktails in Ewings Sarcoma
Weaver, D. T.; Pishas, K. I.; Williamson, D.; Scarborough, J.; Lessnick, S. L.; Dhawan, A.; Scott, J. G.
10.1101/854695 — systems biology — Posted on 2020-03-05
3721 Escherichia coli NusG links the lead ribosome with the transcription elongation complex
Washburn, R.; Zuber, P. K.; Sun, M.; Hashem, Y.; Shen, B.; Li, W.; Harvey, S.; Knauer, S. H.; Frank, J.; Gottesman, M. E.
10.1101/871962 — molecular biology — Posted on 2020-03-05
3723 Thousands of novel unannotated proteins expand the MHC I immunopeptidome in cancer
Ouspenskaia, T.; Law, T.; Clauser, K. R.; Klaeger, S.; Sarkizova, S.; Aguet, F.; Li, B.; Christian, E.; Knisbacher, B. A.; Le, P. M.; Hartigan, C. R.; Keshishian, H.; Apffel, A.; Oliveira, G.; Zhang, W.; Chow, Y. T.; Ji, Z.; Jungreis, I.; Shukla, S. A.; Bachireddy, P.; Kellis, M.; Getz, G.; Hacohen, N.; Keskin, D. B.; Carr, S. A.; Wu, C. J.; Regev, A.
10.1101/2020.02.12.945840 — cancer biology — Posted on 2020-03-05
3725 TALC: Transcription-Aware Long Read Correction
Broseus, L.; Thomas, A.; Oldfield, A.; Sevrac, D.; Dubois, E.; Ritchie, W. J.
10.1101/2020.01.10.901728 — bioinformatics — Posted on 2020-03-05
3726 GPU accelerated partial order multiple sequencealignment for long reads self-correction
Peverelli, F.; Di Tucci, L.; Santambrogio, M. D.; Ding, N.; Hofmeyr, S.; Buluc, A.; Oliker, L.; Yelick, K.
10.1101/2020.02.14.946939 — bioinformatics — Posted on 2020-03-05
3727 DNA transistors switched by the Hofmeister effect
Hoog, T. G.; Pawlak, M. R.; Aufdembrink, L. M.; Bachan, B. R.; Galles, M. B.; Bense, N. B.; Adamala, K. P.; Engelhart, A. E.
10.1101/784561 — synthetic biology — Posted on 2020-03-05
3728 Normative Circuit Dynamics Across Human Cortex During Evidence Accumulation in Changing Environments
Murphy, P. R.; Wilming, N.; Hernandez-Bocanegra, D. C.; Prat Ortega, G.; Donner, T. H.
10.1101/2020.01.29.924795 — neuroscience — Posted on 2020-03-05
3731 Low-density Lipoprotein Receptor-related Protein 5 (LRP5)-deficient Rats Have Reduced Bone Mass and Abnormal Development of the Retinal Vasculature
Ubels, J. L.; Diegel, C. R.; Foxa, G. E.; Ethen, N. J.; Lensing, J. N.; Madaj, Z. B.; VARI Vivarium and Transgenics Core, ; Williams, B. O.
10.1101/2020.01.06.895797 — developmental biology — Posted on 2020-03-05
3733 Fragmentation of extracellular ribosomes and tRNAs shapes the extracellular RNAome
Tosar, J. P.; Segovia, M.; Gambaro, F.; Akiyama, Y.; Fagundez, P.; Costa, B.; Possi, T.; Hill, M.; Ivanov, P.; Cayota, A.
10.1101/2020.01.29.923714 — cell biology — Posted on 2020-03-05
3734 BAG3 Pro209 mutants associated with myopathy and neuropathy relocate chaperones of the CASA-complex to aggresomes
Adriaenssens, E.; Tedesco, B.; Mediani, L.; Asselbergh, B.; Crippa, V.; Antoniani, F.; Carra, S.; Poletti, A.; Timmerman, V.
10.1101/853804 — cell biology — Posted on 2020-03-05
3737 Scedar: a scalable Python package for single-cell RNA-seq exploratory data analysis
Zhang, Y.; Kim, M. S.; Reichenberger, E. R.; Stear, B.; Taylor, D. M.
10.1101/375196 — bioinformatics — Posted on 2020-03-05
3738 The interdomain helix between the kinase and RNase domains of IRE1α transmits the conformational change that underlies ER stress-induced activation.
Ricci, D.; Tutton, S.; Marrocco, I.; Ying, M.; Blumenthal, D.; Eletto, D.; Vargas, J.; Boyle, S.; Fazelinia, H.; Paton, J. C.; Paton, A. W.; Tang, C.-H. A.; Hu, C.-C. A.; Gidalevitz, T.; Argon, Y.
10.1101/2020.01.14.902395 — biochemistry — Posted on 2020-03-05
3739 MAP2 is hyperphosphorylated in schizophrenia, altering its function
Grubisha, M. J.; Sun, X.; MacDonald, M. L.; Garver, M.; Sun, Z.; DeGiosio, R. A.; Lewis, D. A.; Nates, N. A.; Camacho, C.; Homanics, G. E.; Ding, Y.; Sweet, R. A.
10.1101/683912 — neuroscience — Posted on 2020-03-05
3741 Do deep neural networks see the way we do?
Jacob, G.; R. T., P.; Katti, H.; Arun, S.
10.1101/860759 — neuroscience — Posted on 2020-03-05
3742 The Dopamine Receptor Antagonist TFP Prevents Phenotype Conversion and Improves Survival in Mouse Models of Glioblastoma
Bhat, K.; Saki, M.; Vlashi, E.; Cheng, F.; Duhachek-Muggy, S.; Alli, C.; Yu, G.; Medina, P.; He, L.; Damoiseaux, R.; Pellegrini, M.; Zemke, N. R.; Nghiemphu, P. L.; Cloughesy, T. F.; Liau, L. M.; Kornblum, H.; Pajonk, F.
10.1101/870394 — neuroscience — Posted on 2020-03-05
3743 Transposon mobilization in the human fungal pathogen Cryptococcus deneoformans is mutagenic during infection and promotes drug resistance in vitro
Gusa, A.; Williams, J. D.; Cho, J.-E.; Floyd-Averette, A.; Sun, S.; Shouse, E. M.; Heitman, J.; Alspaugh, A.; Jinks-Robertson, S.
10.1101/2020.01.29.924845 — microbiology — Posted on 2020-03-05
3745 Burden analysis of missense variants in 1,330 disease-associated genes on 3D provides insights into the mutation effects
Iqbal, S.; Jespersen, J. B.; Perez-Palma, E.; May, P.; Hoksza, D.; Heyne, H. O.; Ahmed, S. S.; Rifat, Z. T.; Rahman, M. S.; Lage, K.; Palotie, A.; Cottrell, J.; Wagner, F. F.; Daly, M. J.; Campbell, A. J.; Lal, D.
10.1101/693259 — genetics — Posted on 2020-03-05
3749 Comparative analysis of CPI-motif regulation of biochemical functions of actin capping protein
McConnell, P.; Mekel, M.; Kozlov, A. G.; Mooren, O. L.; Lohman, T. M.; Cooper, J. A.
10.1101/2020.02.06.936211 — biochemistry — Posted on 2020-03-05
3750 Altered stomatal patterning accompanies a trichome dimorphism in a natural population of Arabidopsis
Simon, N. M.; Sugisaka, J.; Honjo, M. N.; Aarseth Tunstad, S.; Tunna, G.; Kudoh, H.; Dodd, A. N.
10.1101/710889 — plant biology — Posted on 2020-03-05
3760 Benchmarking of computational error-correction methods for next-generation sequencing data
Mitchell, K.; Mandric, I.; Brito, J.; Wu, Q.; Knyazev, S.; Chang, S.; Martin, L.; Karlsberg, A.; Gerasimov, E.; Littman, R.; Hill, B. L.; Wu, N. C.; Yang, H.; Hsieh, K.; Chen, L.; Shabani, T.; Shabanets, G.; Yao, D.; Sun, R.; Schroeder, J.; Eskin, E.; Zelikovsky, A.; Skums, P.; Pop, M.; Mangul, S.
10.1101/642843 — bioinformatics — Posted on 2020-03-05
3762 Seven-year-olds recall non-adjacent dependencies after overnight retention
Schaadt, G.; Paul, M.; Muralikrishnan, R.; Männel, C.; Friederici, A. D.
10.1101/670257 — neuroscience — Posted on 2020-03-05
3767 ZFP423 regulates early patterning and multiciliogenesis in the hindbrain choroid plexus
Casoni, F.; Croci, L.; Vincenti, F.; Podini, P.; Massimino, L.; Cremona, O.; Consalez, G. G.
10.1101/2020.03.04.975573 — developmental biology — Posted on 2020-03-05
3768 Light-driven formation of high-valent manganese oxide by photosystem II supports evolutionary role in early bioenergetics
Chernev, P.; Fischer, S.; Hoffmann, J.; Oliver, N.; Burnap, R. L.; Zaharieva, I.; Nuernberg, D. J.; Haumann, M.; Dau, H.
10.1101/2020.03.03.975516 — biophysics — Posted on 2020-03-05
3769 Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites
Veenvliet, J. V.; Bolondi, A.; Kretzmer, H.; Haut, L.; Scholze-Wittler, M.; Schifferl, D.; Koch, F.; Pustet, M.; Heimann, S.; Buschow, R.; Wittler, L.; Timmermann, B.; Meissner, A.; Herrmann, B. G.
10.1101/2020.03.04.974949 — developmental biology — Posted on 2020-03-04
3770 Cargo crowding drives sorting stringency in COPII vesicles
Gomez-Navarro, N.; Melero, A.; Boulanger, J.; Kukulski, W.; Miller, E. A.
10.1101/2020.03.04.976183 — cell biology — Posted on 2020-03-04
3776 Comparative analysis of biological aspects of Leishmania infantum isolates
Paes, T.; Charret, K. d. S.; Ribeiro, M. R. d. S.; Rodrigues, R. F.; Leon, L. L.
10.1101/2020.03.04.977462 — pathology — Posted on 2020-03-04
3777 Translocating Mycobacterium ulcerans: an experimental model.
Hammoudi, N.; Fellag, M.; Militello, M.; Bouam, A.; Drancourt, M.
10.1101/2020.03.04.977447 — microbiology — Posted on 2020-03-04
3779 Cathepsin K is required for maintenance and regeneration of lymphopoiesis in vivo
Hausinger, R. I.; Hackl, M.; Jardon Alvarez, A.; Kehr, M.; Romero Marquez, S.; Hettler, F.; Kehr, C.; Grziwok, S.; Schreck, C.; Peschel, C.; Istvanffy, R.; Oostendorp, R.
10.1101/2020.03.04.977496 — cell biology — Posted on 2020-03-04
3780 Global gut content data synthesis and phylogeny delineate reef fish trophic guilds
Parravicini, V.; Casey, J. M.; Schiettekatte, N. M.; Brandl, S.; Pozas-Schacre, C.; Carlot, J.; Edgar, G.; Graham, N. A.; Harmelin-Vivien, M.; Kulbicki, M.; Strona, G.; Stuart-Smith, R.; Vii, J.
10.1101/2020.03.04.977116 — ecology — Posted on 2020-03-04
3781 A global barley panel revealing genomic signatures of breeding in modern cultivars
Hill, C. B.; Angessa, T. T.; Zhang, X.-Q.; Chen, K.; Zhou, G.; Tan, C.; Wang, P.; Westcott, S.; Li, C.
10.1101/2020.03.04.976324 — genomics — Posted on 2020-03-04
3782 RNA editing in inflorescences of wild grapevine unveils association to sex and development
Ramos, M. J. N.; Faisca-Silva, D.; Coito, J. L.; Cunha, J.; Silva, H. G.; Viegas, W.; Costa, M. M. R.; Amancio, S.; Rocheta, M.
10.1101/2020.03.03.974626 — plant biology — Posted on 2020-03-04
3788 Cell-type specific outcome representation in primary motor cortex
Lavzin, M.; Levy, S.; Benisty, H.; Dubin, U.; Brosh, Z.; Aeed, F.; Mensh, B.; Schiller, Y.; Meir, R.; Barak, O.; Talmon, R.; Hantman, A. W.; Schiller, J.
10.1101/2020.03.03.971077 — neuroscience — Posted on 2020-03-04
3789 Hsp27 reduces glycation-induced toxicity and aggregation of α-synuclein
Vicente Miranda, H.; Chegao, A.; Oliveira, M.; Fernandes Gomes, B.; Enguita, F. J.; Outeiro, T. F.
10.1101/2020.03.03.975037 — neuroscience — Posted on 2020-03-04
3795 A draft genome assembly of the eastern banjo frog Limnodynastes dumerilii dumerilii (Anura: Limnodynastidae)
Li, Q.; Guo, Q.; Zhou, Y.; Tan, H.; Bertozzi, T.; Zhu, Y.; Li, J.; Donnellan, S.; Zhang, G.
10.1101/2020.03.03.971721 — genomics — Posted on 2020-03-04
3797 Polygenic adaptation and negative selection across traits, years and environments in a long-lived plant species (Pinus pinaster Ait.)
de Miguel, M.; Rodriguez-Quilon, I.; Heuertz, M.; Hurel, A.; Grivet, D.; Jaramillo-Correa, J. P.; Vendramin, G. G.; Plomion, C.; Majada, J.; Alia, R.; Eckert, A. J.; Gonzalez-Martinez, S. C.
10.1101/2020.03.02.974113 — genetics — Posted on 2020-03-04
3798 Development of Wheat-Aegilops caudata Introgression Lines and Their Characterisation Using Genome-Specific KASP Markers
Grewal, S.; Othmeni, M.; Walker, J.; Hubbart-Edwards, S.; Yang, C.; Scholefield, D.; Ashling, S.; Isaac, P.; King, I.; King, J.
10.1101/2020.03.03.975326 — genetics — Posted on 2020-03-04
3799 Rapid & reversable mutations generate subclonal genetic diversity
Dan, L.; Li, Y.; Chen, S.; Liu, J.; Wang, Y.; Li, F.; He, X.; Carey, L. B.
10.1101/2020.03.03.972455 — genetics — Posted on 2020-03-04
3803 Reprogramming progressive cells display low CAG promoter activity
Hu, X.; Wu, Q.; Jian, Z.; Chen, X.; Hartman, A.; Eastman, A.; Guo, S.
10.1101/2020.03.03.975664 — cell biology — Posted on 2020-03-04
3805 The visual ecology of a color polymorphic reef fish: the role of aggressive mimicry.
Pierotti, M. E.; Wandycz, A.; Wandycz, P.; Rebelein, A.; Corredor, V. H.; Tashiro, J. H.; Castillo, A.; Wcislo, W. T.; McMillan, W. O.; Loew, E. R.
10.1101/2020.03.03.970988 — evolutionary biology — Posted on 2020-03-04
3808 3D printing of Microgel-loaded Modular LEGO-like Cages as Instructive Scaffolds for Tissue Engineering
Hipfinger, C.; Subbiah, R.; Tahayeri, A.; Athirasala, A.; Horsophonphong, S.; Thrivikraman, G.; Franca, C. M.; Cunha, D. A.; Mansoorifar, A.; Zahariev, A.; Jones, J. M.; Coelho, P. G.; Witek, L.; Xie, H.; Guldberg, R. E.; Bertassoni, L. E.
10.1101/2020.03.02.974204 — bioengineering — Posted on 2020-03-04
3814 Novel Human Kidney Cell Subsets Identified by Mux-Seq
Schroeder, A. W.; Sur, S.; Rashmi, P.; Damm, I.; Zarinsefat, A.; Kretzler, M.; Hodgin, J.; Hartoularos, G.; Sigdel, T.; Ye, C. J.; Sarwal, M.; Kidney Precision Medicine Project,
10.1101/2020.03.02.973925 — genomics — Posted on 2020-03-04
3815 Pollinator niche partitioning and asymmetric facilitation contribute to the maintenance of diversity
Wei, N.; Kaczorowski, R. L.; Arceo-Gomez, G.; O'Neill, E. M.; Hayes, R. A.; Ashman, T.-L.
10.1101/2020.03.02.974022 — ecology — Posted on 2020-03-04
3816 Sarcoptic mange; an emerging threat to Chilean wild mammals?
Montecino-Latorre, D.; Napolitano, C.; Briceno, C.; Uhart, M.
10.1101/2020.03.02.974188 — ecology — Posted on 2020-03-04
3819 Saturation of influenza virus neutralization and antibody consumption can both lead to bistable growth kinetics
Xu, S.; Yan, A. W. C.; Peck, H.; Gillespie, L.; Barr, I. G.; Yang, X.; Turner, S. J.; Donato, C. M.; Zhang, T.; Olshansky, M.; Dhanasekaran, V.
10.1101/2020.03.02.973958 — microbiology — Posted on 2020-03-04
3820 Increased Sensitivity and Signal-to-Noise Ratio in Diffusion-Weighted MRI using Multi-Echo Acquisitions
Eichner, C.; Paquette, M.; Mildner, T.; Schlumm, T.; Pleh, K.; Samuni, L.; Crockford, C.; Wittig, R. M.; Jäger, C.; Möller, H. E.; Friederici, A. D.; Anwander, A.
10.1101/2020.03.04.962191 — neuroscience — Posted on 2020-03-04
3821 CryoEM structure of the Vibrio cholerae Type IV competence pilus secretin PilQ
Weaver, S. J.; Sazinsky, M. H.; Dalia, T. N.; Dalia, A. B.; Jensen, G. J.
10.1101/2020.03.03.975896 — biophysics — Posted on 2020-03-04
3824 A unifying model to predict variable drug response for personalised medicine
van der Lee, M.; Allard, W. G.; Vossen, R. H. A. M.; Baak-Pablo, R. F.; Menafra, R.; Deiman, B. A. L. M.; Deenen, M. J.; Neven, P.; Johansson, I.; Gastaldello, S.; Ingelman-Sundberg, M.; Guchelaar, H.-J.; Swen, J. J.; Anvar, S. Y.
10.1101/2020.03.02.967554 — pharmacology and toxicology — Posted on 2020-03-04
3826 Sapphire Nanopores for Low-Noise DNA Sensing
Xia, P.; Zuo, J.; Paudel, P.; Choi, S.; Chen, X.; Song, W.; Im, J.; Wang, C.
10.1101/2020.03.02.973826 — bioengineering — Posted on 2020-03-04
3829 Fast oscillations localize the epileptogenic zone: an electrical source imaging study using high-density electroencephalography
Avigdor, T.; Abdallah, C.; von Ellenrieder, N.; Rubino, A.; Lo Russo, G.; Bernhardt, B.; Nobili, L.; Grova, C.; Frauscher, B.
10.1101/2020.03.02.973602 — neuroscience — Posted on 2020-03-04
3832 Improving replicability in single-cell RNA-Seq cell type discovery with Dune
Roux de Bezieux, H.; Street, K.; Fischer, S.; Van den Berge, K.; Chance, R.; Risso, D.; Gillis, J.; Ngai, J.; Purdom, E.; Dudoit, S.
10.1101/2020.03.03.974220 — bioinformatics — Posted on 2020-03-04
3835 Functional modeling of NMIHBA-causing PRUNE1 variants reveals a requirement for its exopolyphosphatase activity.
Nistala, H.; Dronzek, J.; Gonzaga-Jauregui, C.; Man Chim, S.; Rajamani, S.; Nuwayhid, S.; Delgado, D.; Burke, E.; Karaca, E.; Franklin, M. C.; Sarangapani, P.; Podgorski, M.; Tang, Y.; Dominguez, M. G.; Withers, M.; Deckelbaum, R. A.; Scheonherr, C. J.; Gahl, W. A.; Malicdan, M. C.; Zambrowicz, B.; Gale, N. W.; Gibbs, R. A.; Chung, W. K.; Lupski, J. R.; Economides, A. N.
10.1101/2020.03.02.973909 — genetics — Posted on 2020-03-04
3836 Genomic characterization of the adolescent idiopathic scoliosis associated transcriptome and regulome
Makki, N.; Zhao, J.; Liu, Z.; Eckalbar, W.; Ushiki, A.; Khanshour, A.; Wu, Z.; Rios, J.; Gray, R.; Wise, C.; Ahituv, N.
10.1101/2020.03.02.973735 — genetics — Posted on 2020-03-04
3839 Intragenic Complementation of Cellulose Synthase-Like D1 alleles in Root Hair Development
Karas, B.; Ross, L.; Novero, M.; Amyot, L.; Inada, S.; Nakano, M.; Sakai, T.; Sato, S.; Murray, J. D.; Bonfante, P.; Szczyglowski, K.
10.1101/2020.03.02.973545 — plant biology — Posted on 2020-03-04
3841 The INO80 remodeler couples premature termination of mRNA synthesis with transcription elongation
Luzzi, S.; Szachnowski, U.; Greener, S.; Han, K. H.; Darke, J.; Piccinno, R.; Lafon, A.; Pugh, B. F.; Morillon, A.; Papamichos-Chronakis, M.
10.1101/2020.03.02.973685 — molecular biology — Posted on 2020-03-04
3843 Molecular determinants and heterogeneity of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing
Kurd, N.; He, Z.; Milner, J.; Omilusik, K.; Louis, T.; Tsai, M.; Widjaja, C.; Kanbar, J.; Olvera, J.; Tysl, T.; Quezada, L.; Boland, B.; Huang, W.; Murre, C.; Goldrath, A.; Yeo, G.; Chang, J.
10.1101/2020.03.02.973578 — immunology — Posted on 2020-03-04
3845 Phylogenomics of piranhas and pacus (Serrasalmidae) uncovers how convergent diets obfuscate traditional morphological taxonomy.
Kolmann, M. A.; Hughes, L. C.; Hernandez, L. P.; Arcila, D.; Betancur-R., R.; Sabaj, M. H.; Lopez-Fernandez, H.; Orti, G.
10.1101/2020.03.02.973503 — evolutionary biology — Posted on 2020-03-04
3849 Bayesian Structural Time Series for Mobile Health and Sensor Data: A Flexible Modeling Framework for Evaluating Interventions
Liu, J.; Spakowicz, D. J.; Hoyd, R.; Ash, G. I.; Lou, S.; Lee, D.; Zhang, J.; Presley, C.; Greene, A.; Papachristos, A. V.; Gerstein, M.
10.1101/2020.03.02.973677 — bioinformatics — Posted on 2020-03-04
3850 Mechanosensitive activation of mTORC1 mediates ventilator induced lung injury during the acute respiratory distress syndrome
Lee, H.; Fei, Q.; Streicher, A.; Zhang, W.; Isabelle, C.; Patel, P.; Lam, H. C.; Pinilla-Vera, M.; Amador-Munoz, D.; Barragan-Bradford, D.; Higuera, A.; Putman, R. K.; Henske, E. P.; Bobba, C. M.; Higuita-Castro, N.; Hite, R. D.; Christman, J. W.; Ghadiali, S. N.; Baron, R. M.; Englert, J.
10.1101/2020.03.02.973081 — molecular biology — Posted on 2020-03-04
3851 Proteomics support the threespine stickleback egg coat as a protective oocyte envelope
Killingbeck, E. E.; Wilburn, D. B.; Merrihew, G. E.; MacCoss, M. J.; Swanson, W.
10.1101/2020.03.04.976316 — molecular biology — Posted on 2020-03-04
3853 Limited Environmental Serine Confers Sensitivity to PHGDH Inhibition in Brain Metastasis
Ngo, B.; Kim, E.; Osorio-Vasquez, V.; Doll, S.; Bustraan, S.; Luengo, A.; Davidson, S. M.; Ali, A.; Ferraro, G. D.; Kang, D.; Ni, J.; Liang, R.; Plasger, A.; Kastenhuber, E. R.; Eskandari, R.; Bacha, S.; Siriam, R. K.; Bakhoum, S. F.; Mullarky, E.; Snuderl, M.; Mainolfi, N.; Suri, V.; Friedman, A.; Manfredi, M.; Sabatini, D. M.; Jones, D.; Yu, M.; Zhao, J. J.; Jain, R. K.; Vander Heiden, M. G.; Hernando, E.; Mann, M.; Cantley, L. C.; Pacold, M. E.
10.1101/2020.03.03.974980 — cancer biology — Posted on 2020-03-04
3855 Motif analysis in co-expression networks reveals regulatory elements in plants: The peach as a model
Ksouri, N.; Castro-Mondragon, J. A.; Montardit-Tarda, F.; van Helden, J.; Contreras-Moreira, B.; Gogorcena, Y.
10.1101/2020.02.28.970137 — genomics — Posted on 2020-03-04
3856 SLC45A2 protein stability and regulation of melanosome pH determine melanocyte pigmentation
Marks, M. S.; Le, L.; Escobar, I. E.; Ho, T.; Lefkovith, A. J.; Latteri, E.; Haltaufderhyde, K. D.; Sviderskaya, E. V.; Bennett, D. C.; Oancea, E.; Dennis, M. K.
10.1101/2020.03.03.974881 — cell biology — Posted on 2020-03-04
3857 A metabolic shift to glycolysis promotes zebrafish tail regeneration through TGF-β dependent dedifferentiation of notochord cells to form the blastema
Sinclair, J. W.; Hoying, D. R.; Bresciani, E.; Dalle Nogare, D.; Needle, C. D.; Wu, W.; Bishop, K.; Elkahloun, A. G.; Chitnis, A.; Liu, P. P.; Burgess, S. M.
10.1101/2020.03.03.975318 — developmental biology — Posted on 2020-03-04
3859 CDKN2C homozygous loss identifies a distinct subtype of TP53/RB1-wildtype leiomyosarcoma with frequent CIC genomic alterations and 1p/19q-codeletion
Williams, E. A.; Sharaf, R.; Decker, B.; Werth, A. J.; Toma, H.; Montesion, M.; Sokol, E. S.; Pavlick, D. C.; Shah, N.; Venstrom, J. M.; Alexander, B. M.; Ross, J. S.; Albacker, L. A.; Lin, D. I.; Ramkissoon, S. H.; Elvin, J. A.
10.1101/2020.03.02.973305 — cancer biology — Posted on 2020-03-04
3862 Out-of-register parallel β-sheets and antiparallel β-sheets coexist in 150 kDa oligomers formed by Aβ(1-42)
Gao, Y.; Guo, C.; Watzlawik, J. O.; Lee, E. J.; Huang, D.; Zhou, H.-X.; Rosenberry, T. L.; Paravastu, A. K.
10.1101/2020.03.03.974394 — biochemistry — Posted on 2020-03-04
3864 CO2 reduction driven by a pH gradient
Hudson, R.; de Graaf, R.; Strandoo Rodin, M.; Ohno, A.; Lane, N.; McGlynn, S. E.; Yamada, Y. M. A.; Nakamura, R.; Barge, L. M.; Braun, D.; Sojo, V.
10.1101/2020.03.02.973982 — biochemistry — Posted on 2020-03-04
3865 Construction of habitat-specific training sets to achieve species-level assignment in 16S rRNA gene datasets
Escapa, I. F.; Huang, Y.; Chen, T.; Lin, M.; Kokaras, A.; Dewhirst, F. E.; Lemon, K. P.
10.1101/791574 — microbiology — Posted on 2020-03-04
3871 Flexible Modulation of Neural Variance Facilitates Neuroprosthetic Skill Learning
You, A. K.; Liu, B.; Singhal, A.; Gowda, S.; Moorman, H.; Orsborn, A.; Ganguly, K.; Carmena, J. M.
10.1101/817346 — neuroscience — Posted on 2020-03-04
3875 Dolosigranulum pigrum cooperation and competition in human nasal microbiota
Brugger, S. D.; Eslami, S. M.; Pettigrew, M. M.; Fernandez Escapa, I.; Henke, M. M.; Kong, Y.; Lemon, K. P.
10.1101/678698 — microbiology — Posted on 2020-03-04
3876 A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding
Akbar, R.; Robert, P. A.; Pavlovic, M.; Jeliazkov, J. R.; Snapkov, I.; Slabodkin, A.; Weber, C. R.; Scheffer, L.; Miho, E.; Haff, I. H.; Tryslew Haug, D. T.; Lund-Johansen, F.; Safonova, Y.; Sandve, G. K.; Greiff, V.
10.1101/759498 — immunology — Posted on 2020-03-04
3877 Collateral fitness effects of mutations
Mehlhoff, J. D.; Stearns, F. W.; Rohm, D.; Wang, B.; Tsou, E.-Y.; Dutta, N.; Hsiao, M.-H.; Gonzalez, C. E.; Rubin, A. F.; Ostermeier, M.
10.1101/820068 — evolutionary biology — Posted on 2020-03-04
3879 Clathrin light chain diversity regulates budding efficiency in vitro and synaptic vesicle formation in vivo
Redlingshoefer, L.; McLeod, F.; Camus, M. D.; Chen, Y.; Burden, J. J.; Palomer, E.; Briant, K.; Dannhauser, P. N.; Salinas, P. C.; Brodsky, F.
10.1101/815183 — cell biology — Posted on 2020-03-04
3880 MicrographCleaner: a python package for cryo-EM micrograph cleaning using deep learning
Sanchez-Garcia, R.; Segura, J.; Maluenda, D.; Sorzano, C. O. S.; Carazo, J. M.
10.1101/677542 — bioinformatics — Posted on 2020-03-04
3881 3D-printed moulds for image-guided surgical biopsies: an open source computational platform
Mireia, C.-O.; Gehrung, M.; Ursprung, S.; Gill, A. B.; Warren, A. Y.; Beer, L.; Gallagher, F. A.; Mitchell, T. J.; Mendichovszky, I. A.; Priest, A. N.; Stewart, G. D.; Sala, E.; Markowetz, F.
10.1101/658831 — bioengineering — Posted on 2020-03-04
3882 The Hex-Maze: A previous knowledge and schema task for mice
Alonso, A.; Bokeria, L.; van der Meij, J.; Samanta, A.; Eichler, R.; Spooner, P.; Navarro Lobato, I.; Genzel, L.
10.1101/441048 — animal behavior and cognition — Posted on 2020-03-04
3886 Identification of Adomavirus Virion Proteins
Welch, N. L.; Tisza, M. J.; Starrett, G. J.; Belford, A. K.; Pastrana, D. V.; Pang, Y.-Y. S.; Schiller, J. T.; An, P.; Cantalupo, P. G.; Pipas, J. M.; Koda, S.; Subramaniam, K.; Waltzek, T. B.; Bian, C.; Shi, Q.; Ruan, Z.; Ng, T. F. F.; Buck, C. B.
10.1101/341131 — microbiology — Posted on 2020-03-04
3889 Deep learning-based cross-classifications reveal conserved spatial behaviors within tumor histological images
Noorbakhsh, J.; Farahmand, S.; Foroughi pour, A.; Namburi, S.; Caruana, D.; Rimm, D.; Soltanieh-ha, M.; Zarringhalam, K.; Chuang, J. H.
10.1101/715656 — bioinformatics — Posted on 2020-03-04
3890 TCF7L2 regulates postmitotic differentiation programs and excitability patterns in the thalamus
Lipiec, M. A.; Kozinski, K.; Zajkowski, T.; Bem, J.; Urban-Ciecko, J.; Dabrowski, M.; Chakraborty, C.; Szewczyk, L. M.; Toval, A.; Ferran, J.; Nagalski, A.; Wisniewska, M. B.
10.1101/515874 — neuroscience — Posted on 2020-03-04
3891 Glucocorticoids and cortical decoding in the phobic brain
Schwab, S.; Federspiel, A.; Morishima, Y.; Nakataki, M.; Strik, W.; Wiest, R.; Heinrichs, M.; de Quervain, D.; Soravia, L. M.
10.1101/099697 — neuroscience — Posted on 2020-03-04
3892 Quantitative fluxomics of circulating metabolites
Hui, S. T.; Cowan, A. J.; Zeng, X.; Yang, L.; TeSlaa, T.; Li, X.; Bartman, C.; Zhang, Z.; Jang, C.; Wang, L.; Lu, W.; Rojas, J.; Baur, J.; Rabinowitz, J.
10.1101/2020.03.02.973669 — systems biology — Posted on 2020-03-03
3896 Role of RgsA in oxidative stress resistance in Pseudomonas aeruginosa
Hou, S.; Zhang, J.; Ma, X.; Hong, Q.; Fang, L.; Zheng, G.; Huang, J.; Gao, Y.; Xu, Q.; Zhuang, X.; Song, X.
10.1101/2020.03.03.974683 — microbiology — Posted on 2020-03-03
3897 Green Fabricated Zinc Oxide Nanoformulated Media Enhanced Callus Induction and Regeneration Dynamics of Panicum virgatum L.
Shafique, S.; Jabeen, N.; Ahmad, K. S.; Irum, S.; Anwaar, S.; Ahmad, N.; Alam, S.; Ilyas, M.; Khan, T. F.; Hussain, S. Z.
10.1101/2020.03.03.974675 — plant biology — Posted on 2020-03-03
3899 Ageing compromises mouse thymus function and remodels epithelial cell differentiation
Ponting, C. P.; Baran-Gale, J.; Morgan, M. D.; Maio, S.; Dhalla, F.; Calvo-Asensio, I.; Deadman, M.; Handel, A. E.; Maynard, A.; Chen, S.; Green, F.; Sit, R.; Neff, N.; Darmanis, S.; Tan, W.; May, A. P.; Marioni, J. C.; Holländer, G. A.
10.1101/2020.03.02.973008 — immunology — Posted on 2020-03-03
3900 A new role for histone demethylases in the maintenance of plant genome integrity
Antunez-Sanchez, J.; Naish, M.; Ramirez-Prado, J. S.; Ohno, S.; Huang, Y.; Dawson, A.; Manza-Mianza, D.; Ariel, F.; Raynaud, C.; Wibowo, A.; Daron, J.; Ueda, M.; Latrasse, D.; Slotkin, R. K.; Weigel, D.; Benhamed, M.; Gutierrez-Marcos, J.
10.1101/2020.03.02.972752 — plant biology — Posted on 2020-03-03
3901 Mechanical Regulation of the Cytotoxic Activity of Natural Killer Cells
Mordechay, L.; Edri, A.; Hadad, U.; Porgador, A.; Schvartzman, M.; Le Saux, G.
10.1101/2020.03.02.972984 — immunology — Posted on 2020-03-03
3905 Defining totipotency using criteria of increasing stringency
Posfai, E.; Schell, J. P.; Janiszewski, A.; Rovic, I.; Murray, A.; Bradshaw, B.; Pardon, T.; El Bakkali, M.; Talon, I.; De Geest, N.; Kumar, P.; To, S. K.; Petropoulos, S.; Jurisicova, A.; Pasque, V.; Lanner, F.; Rossant, J.
10.1101/2020.03.02.972893 — cell biology — Posted on 2020-03-03
3906 Identification and Optimization of cell active 4-anilino-quin(az)oline Inhibitors for Protein Kinase Novel 3 (PKN3)
Asquith, C. R. M.; Temme, L.; Laitinen, T.; Pickett, J.; Kwarcinski, F. E.; Sinha, P.; Wells, C. I.; Tizzard, G. J.; Zutshi, R.; Drewry, D. H.
10.1101/2020.03.02.972943 — pharmacology and toxicology — Posted on 2020-03-03
3909 Microbiological water quality of Managed Aquifer Recharge systems in the salinity-prone southwest coastal Bangladesh
Doza, S.; Naser, A. M.; Rahman, M. M.; Mondol, M. H.; Khan, G. K.; Uddin, M. N.; Gazi, M. S.; Alam, G. R.; Karim, M. R.; Ahmed, K. M.; Luby, S. P.; Clasen, T.; Unicomb, L.
10.1101/2020.03.02.972372 — microbiology — Posted on 2020-03-03
3910 A lipid metabolic map of the pathogenic fungus Histoplasma capsulatum
Zamith-Miranda, D.; Heyman, H. M.; Burnet, M. C.; Couvillion, S. P.; Zheng, X.; Munoz, N.; Kyle, J. E.; Zink, E. M.; Weitz, K. K.; Bloodsworth, K. J.; Clair, G. C.; Zucker, J. D.; Teuton, J. R.; Payne, S. H.; Kim, Y.-M.; Reyes Gil, M.; Baker, E. S.; Bredeweg, E. L.; Nosanchuk, J. D.; Nakayasu, E. S.
10.1101/2020.03.02.973412 — microbiology — Posted on 2020-03-03
3911 Streptococcus pyogenes M1T1 variants induce an inflammatory phenotype in neutrophils
Williams, J. G.; Ly, D.; Geraghty, N. J.; McArthur, J. D.; Vyas, H.; Gorman, J.; Tsatsaronis, J. A.; Sluyter, R.; Sanderson-Smith, M. L.
10.1101/2020.03.02.972240 — microbiology — Posted on 2020-03-03
3912 Transferrin-dependent crosstalk between the intestinal tract and commensal microbes contributes for immune tolerance
Tang, X.; Fang, M.; Xu, K.; Cheng, R.; Wang, G.; Liao, Z.; Zhang, Z.; Mwangi, J.; Lu, Q.; Lai, R.
10.1101/2020.03.02.972281 — immunology — Posted on 2020-03-03
3916 A framework to identify structured behavioral patterns within rodent spatial trajectories
Donnarumma, F.; Prevete, R.; Maisto, D.; Fuscone, A.; van der Meer, M.; Kemere, C.; Pezzulo, G.
10.1101/2020.03.02.967489 — animal behavior and cognition — Posted on 2020-03-03
3920 MiRNA and phasiRNAs-mediated regulation of TIR-NBS-LRR defense genes in Arabidopsis thaliana
Lopez-Marquez, D.; Del-Espino, A.; Lopez-Pagan, N.; Rodriguez-Negrete, E. A.; Rubio-Somoza, I.; Ruiz-Albert, J.; Bejarano, E. R.; Beuzon, C. R.
10.1101/2020.03.02.972620 — plant biology — Posted on 2020-03-03
3923 p38delta genetic ablation protects female mice from anthracycline cardiotoxicity
George, S. A.; Kiss, A.; Obaid, S. N.; Venegas, A.; Talapatra, T.; Wei, C.; Efimova, T.; Efimov, I. R.
10.1101/2020.03.02.973347 — physiology — Posted on 2020-03-03
3924 Meta-analysis of the effects of sleep deprivation on depression in patients and animals
Hu, B.; Ye, M.; Feng, D.; Ying, J.; Mou, T.; Luo, F.; Lv, T.; Jiang, L.; Qian, C.; Ding, Z.; Yu, C.; Gao, H.; Zhang, J.; Liu, Z.
10.1101/2020.03.02.971689 — neuroscience — Posted on 2020-03-03
3932 UC2 - A Versatile and Customizable low-cost 3D-printed Optical Open-Standard for microscopic imaging
Diederich, B.; Lachmann, R.; Carlstedt, S.; Marsikova, B.; Wang, H.; Uwurukundu, X.; Mosig, A.; Heintzmann, R.
10.1101/2020.03.02.973073 — bioengineering — Posted on 2020-03-03
3933 Mediator-Microorganism Interaction in Microbial Solar Cell: a Fluo-Electrochemical Insight
BEAUZAMY, L.; DELACOTTE, J.; BAILLEUL, B.; Tanaka, K.; NAKANISHI, S.; WOLLMAN, F.-A.; LEMAITRE, F.
10.1101/2020.03.01.970954 — biophysics — Posted on 2020-03-03
3934 Full quantum mechanical modeling of the enzyme-substrate system: how laccase detoxifies aflatoxin
Zaccaria, M.; Dawson, W.; Kish, D. R.; Reverberi, M.; Domin, M.; Dellafiora, L.; Nakajima, T.; Genovese, L.; Momeni, B.
10.1101/2020.03.02.973883 — biophysics — Posted on 2020-03-03
3936 The transcription and export complex THO/TREX contributes to transcription termination in plants
Khan, G. A.; Deforges, J.; Reis, R. S.; Hsieh, Y.-F.; Montpetit, J.; Antosz, W.; Santuari, L.; Hardtke, C. S.; Grasser, K.; Poirier, Y.
10.1101/2020.03.02.972356 — plant biology — Posted on 2020-03-03
3940 Essential PBP1-associated proteins of Trypanosoma brucei
Nascimento, L.; Terrao, M.; Marucha, K. K.; Liu, B.; Egler, F.; Clayton, C.
10.1101/2020.03.02.973057 — molecular biology — Posted on 2020-03-03
3941 Nonsense mediated RNA decay factor UPF1 is critical for post-transcriptional and translational gene regulation in Arabidopsis
Raxwal, V. K.; Simpson, C. G.; Gloggnitzer, J.; Entinze, J. C.; Guo, W.; Zhang, R.; Brown, J. W.; Riha, K.
10.1101/2020.03.02.971978 — molecular biology — Posted on 2020-03-03
3942 Isolation and characterization of SARS-CoV-2 from the first US COVID-19 patient
Harcourt, J.; Tamin, A.; Lu, X.; Kamili, S.; Kumar Sakthivel, S.; Wang, L.; Murray, J.; Queen, K.; Lynch, B.; Whitaker, B.; Tao, Y.; Paden, C.; Zhang, J.; Li, Y.; Uehara, A.; Wang, H.; Goldsmith, C.; Bullock, H.; Gautam, R.; Schindewolf, C.; Lokugamage, K. G.; Scharton, D.; Plante, J.; Mirchandani, D.; Widen, S.; Narayanan, K.; Makino, S.; Ksiazek, T.; Plante, K. S.; Weaver, S.; Menachery, V. D.; Thornburg, N. J.
10.1101/2020.03.02.972935 — microbiology — Posted on 2020-03-03
3946 A Microfluidic Platform for Functional Testing of Cancer Drugs on Intact Tumor Slices
Rodriguez, A. D.; Horowitz, L. F.; Castro, K.; Kenerson, H.; Bhattacharjee, N.; Gandhe, G.; Raman, A.; Monnat, R. J.; Yeung, R. S.; Rostomily, R. C.; Folch, A.
10.1101/2020.03.02.973818 — bioengineering — Posted on 2020-03-03
3947 Animal personality adds complexity to the processes of adaptive divergence and speciation.
Horta-Lacueva, Q. J.-B.; Benhaim, D.; Morrissey, M.; Snorrason, S. S.; Kapralova, K. H.
10.1101/2020.03.02.971614 — evolutionary biology — Posted on 2020-03-03
3948 Heme A-containing oxidases evolved in the ancestors of iron oxidizing bacteria
Degli Esposti, M.; Garcia-Meza, V.; Ceniceros Gomez, A.; Moya-Beltran, A.; Quatrini, R.; Hedersted, L.
10.1101/2020.03.01.968255 — evolutionary biology — Posted on 2020-03-03
3950 A computational framework to explore cellular response mechanisms from multi-omics datasets
Pino, J. C.; Lubbock, A. L. R.; Harris, L. A.; Gutierrez, D. B.; Farrow, M. A.; Muszynski, N.; Tsui, T.; Norris, J. L.; Caprioli, R. M.; Wikswo, J. P.; Lopez, C. F.
10.1101/2020.03.02.974121 — systems biology — Posted on 2020-03-03
3951 A transferrable and interpretable multiple instance learning model for microsatellite instability prediction based on histopathology images
Dong, Z.-Y.; Cao, R.; Yang, F.; Ma, S.-C.; Liu, L.; Wu, D.-H.; Li, Y.; Zhao, Y.; Wang, T.; Lu, W.-J.; Cai, W.-J.; Zhu, H.-B.; Guo, X.-J.; Lu, Y.-W.; Kuang, J.-J.; Huan, W.-J.; Tang, W.; Huang, J.; Yao, J.
10.1101/2020.02.29.971150 — bioengineering — Posted on 2020-03-03
3953 Salt tolerance QTL derived from the Bangladeshi landrace Horkuch
Haque, T.; Elias, S. M.; Razzaque, S.; Sudip Biswas, S.; Khan, S. F.; Jewel, N. A.; Rahman, S.; Juenger, T.; Seraj, Z. I.
10.1101/2020.03.01.971895 — plant biology — Posted on 2020-03-03
3955 Applying a gene-suite approach to examine the physiological status of wild-caught walleye (Sander vitreus)
Jeffrey, J. D.; Carlson, H.; Wrubleski, D.; Enders, E. C.; Treberg, J. R.; Jeffries, K. M.
10.1101/2020.02.29.971374 — physiology — Posted on 2020-03-03
3956 ABO blood group, glycosyltransferase activity and risk of Venous Thrombosis
IBRAHIM-KOSTA, M.; Bailly, P.; SILVY, M.; Saut, N.; Suchon, P.; MORANGE, P.; Chiaroni, J.; Tregouet, D.-A.; Goumidi, L.
10.1101/2020.03.01.971754 — pathology — Posted on 2020-03-03
3957 Intracranial recordings demonstrate medial temporal lobe engagement in visual search in humans
Slama, K.; Jimenez, R.; Saha, S.; King-Stephens, D.; Laxer, K. D.; Weber, P. B.; Endestad, T.; Larsson, P. G.; Solbakk, A.-K.; Lin, J. J.; Knight, R. T.
10.1101/2020.02.29.971341 — neuroscience — Posted on 2020-03-03
3962 Population-based body-brain mapping links brain morphology and body composition
Gurholt, T. P.; Kaufmann, T.; Frei, O.; Alnaes, D.; Haukvik, U. K.; van der Meer, D.; Moberget, T.; O'Connell, K. S.; Leinhard, O. D.; Linge, J.; Simon, R.; Smeland, O. B.; Sonderby, I. E.; Winterton, A.; Steen, N. E.; Westlye, L. T.; Andreassen, O. A.
10.1101/2020.02.29.970095 — neuroscience — Posted on 2020-03-03
3966 pAgo-induced DNA interference protects bacteria from invader DNA
Kuzmenko, A.; Oguienko, A.; Esyunina, D.; Yudin, D.; Petrova, M.; Kudinova, A.; Maslova, O.; Ninova, M.; Ryazansky, S.; Leach, D.; Aravin, A. A.; Kulbachinskiy, A.
10.1101/2020.03.01.971358 — molecular biology — Posted on 2020-03-03
3967 Colonization with heterologous bacteria reprograms a Caenorhabditis elegans nutritional phenotype
Sun, Q.; Vega, N. M.; Cervantes, B.; Mancuso, C.; Mao, N.; Taylor, M. N.; Collins, J. J.; Khalil, A. S.; Gore, J.; Lu, T. K.
10.1101/2020.03.01.972349 — microbiology — Posted on 2020-03-03
3969 The Vpu-interacting protein ATP6V0C regulates expression of tetherin and HIV-1 release
Waheed, A. A.; Swiderski, M.; Khan, A.; Gitzen, A.; Majadly, A.; Freed, E. O.
10.1101/2020.03.01.972125 — microbiology — Posted on 2020-03-03
3970 A rank-normalized archaeal taxonomy based on genome phylogeny resolves widespread incomplete and uneven classifications
Rinke, C.; Chuvochina, M.; Mussig, A. J.; Chaumeil, P.-A.; Waite, D. W.; Whitman, W. B.; Parks, D. H.; Hugenholtz, P.
10.1101/2020.03.01.972265 — microbiology — Posted on 2020-03-03
3971 Children Developing Celiac Disease Have a Distinct and Proinflammatory Gut Microbiota in the First 5 Years of Life
Huang, Q.; Yang, Y.; Tolstikov, V.; Kiebish, M. A.; ludvigsson, J. F.; Palm, N. W.; Ludvigsso, J.; ALTINDIS, E.
10.1101/2020.02.29.971242 — microbiology — Posted on 2020-03-03
3972 Spatial organization of the kelp microbiome at micron scales
Ramirez-Puebla, S. T.; Weigel, B. L.; Jack, L.; Schlundt, C.; Pfister, C. A.; Mark Welch, J. L.
10.1101/2020.03.01.972083 — microbiology — Posted on 2020-03-03
3973 Integrated role of microRNA-30e-5p through targeting negative regulators of innate immune pathways during HBV infection and SLE
Mishra, R.; Bhattacharya, S.; Rawat, B. S.; Kumar, A.; Kumar, A.; Niraj, K.; Chande, A.; Gandhi, P.; Khetan, D.; Aggarwal, A.; Sato, S.; Tailor, P.; Takaoka, A. T.; Kumar, H.
10.1101/2020.02.29.969014 — immunology — Posted on 2020-03-03
3979 Population Structure in a Direct-Developing Marine Isopod
Pearman, W. S.; Wells, S. J.; Silander, O. K.; Freed, N. E.; Dale, J.
10.1101/2020.03.01.971333 — ecology — Posted on 2020-03-03
3982 Cetaceans of the Black Sea: where did they survive glacial?
Dekanoidze, D.; Kopaliani, N.; Gurielidze, Z.; Ninua, L.; Devidze, N.; Tarkhnishvili, D.
10.1101/2020.03.02.972463 — ecology — Posted on 2020-03-03
3986 Assessing the effects of stand dynamics on stem growth allocation of individual Scots pine trees
Saarinen, N.; Kankare, V.; Yrttimaa, T.; Viljanen, N.; Honkavaara, E.; Holopainen, M.; Hyyppa, J.; Huuskonen, S.; Hynynen, J.; Vastaranta, M.
10.1101/2020.03.02.972521 — ecology — Posted on 2020-03-03
3991 Pod and seed trait QTL identification to assist breeding for peanut market preferences
Chavarro, C.; Chu, Y.; Holbrook, C. C.; Isleib, T.; Bertioli, D.; Hovav, R.; Butts, C.; Marshall, L.; Sorensen, R.; Jackson, S. A.; Ozias-Akins, P.
10.1101/738914 — plant biology — Posted on 2020-03-03
3992 Oil body formation in Marchantia polymorpha is controlled by MpC1HDZ and serves as a defense against arthropod herbivores
Romani, F.; Banic, E.; Florent, S. N.; Kanazawa, T.; Goodger, J. Q. D.; Mentink, R.; Dierschke, T.; Zachgo, S.; Ueda, T.; Bowman, J. L.; Tsiantis, M.; Moreno, J. E.
10.1101/2020.03.02.971010 — plant biology — Posted on 2020-03-03
3994 A Novel Non-hypermucoviscous ST11 Hypervirulent Carbapenem-resistant Klebsiella pneumoniae Lacking Classical Virulence Factors
Zhang, M.; Zhang, J.; Li, J.; Xu, S.; Hu, C.; Deng, Q.; Wu, X.; Xiao, L.; Liu, Z.; Yang, X.; Hu, X.; Zhang, W.; Wang, N.; Yang, L.; Liu, S.; Cui, R.; Hui, Z.; Zhong, Y.; Luo, Y.; Chen, H.; Wu, W.; Wu, J.; Lu, Y.; Liu, X.; Zou, Q.; Huang, W.
10.1101/2020.02.28.970863 — microbiology — Posted on 2020-03-03
3996 B cells engineered to express an anti-HIV antibody allow memory retention, class switch recombination and clonal selection in mice
Nahmad, A. D.; Raviv, Y.; Horovitz-Fried, M.; Sofer, I.; Akriv, T.; Nataf, D.; Dotan, I.; Burstein, D.; Wine, Y.; Benhar, I.; Barzel, A.
10.1101/2020.02.28.970822 — immunology — Posted on 2020-03-03
3997 Description and Validation of the Colorectal Cancer and Adenoma Incidence & Mortality (CRC-AIM) Microsimulation Model
Piscitello, A.; Saoud, L.; Matney, M.; Borah, B. J.; Fendrick, A. M.; Lich, K. H.; Rinde, H.; Limburg, P. J.
10.1101/2020.03.02.966838 — cancer biology — Posted on 2020-03-03
4003 Evidence for RNA editing in the transcriptome of 2019 Novel Coronavirus
Di Giorgio, S.; Martignano, F.; Torcia, M. G.; Mattiuz, G.; Conticello, S. G.
10.1101/2020.03.02.973255 — bioinformatics — Posted on 2020-03-03
4004 Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2
Kim, Y.; Jedrzejczak, R.; Maltseva, N. I.; Endres, M.; Godzik, A.; Michalska, K.; Joachimiak, A.
10.1101/2020.03.02.968388 — molecular biology — Posted on 2020-03-03
4006 Multi-epitope vaccine design using an immunoinformatics approach for 2019 novel coronavirus in China (SARS-CoV-2)
Feng, Y.; Qiu, M.; Zou, S.; Li, Y.; Luo, K.; Chen, R.; Sun, Y.; Wang, K.; Zhuang, X.; Zhang, S.; Chen, S.; Mo, F.
10.1101/2020.03.03.962332 — bioinformatics — Posted on 2020-03-03
4007 Validity of dynamical analysis to characterize heart rate and oxygen consumption during effort tests
Mongin, D.; Chabert, C.; Uribe Caparros, A.; Collado, A.; Hermand, E.; Hue, O.; Alvero Cruz, J. R.; Courvoisier, D. S.
10.1101/2020.02.29.971119 — bioinformatics — Posted on 2020-03-03
4009 A machine learning approach for Colles' fracture treatment diagnosis
Ngan, K. H.; d'Avila Garcez, A.; Knapp, K. M.; Appelboam, A.; Reyes-Aldasoro, C. C.
10.1101/2020.02.28.970574 — bioinformatics — Posted on 2020-03-03
4010 The complex relationship between effort and heart rate: a hint from dynamical analysis
Mongin, D.; Chabert, C.; Uribe Caparros, A.; Vico Guzman, J. F.; Hue, O.; Alvero Cruz, J. R.; Courvoisier, D. S.
10.1101/2020.03.01.971929 — bioinformatics — Posted on 2020-03-03
4011 Defining Strawberry Uniformity using 3D Imaging and Genetic Mapping
Li, B.; Cockerton, H. M.; Johnson, A. W.; Karlstrom, A.; stavridou, E.; Deakin, G.; Harrison, R. J.
10.1101/2020.03.01.972190 — bioinformatics — Posted on 2020-03-03
4014 The lateral hypothalamus and orexinergic transmission in the paraventricular thalamus promote the attribution of incentive salience to reward-associated cues
Haight, J. L.; Campus, P.; Maria-Rios, C. E.; Johnson, A. M.; Klumpner, M. S.; Kuhn, B. N.; Covelo, I. R.; Morrow, J. D.; Flagel, S.
10.1101/2020.03.01.972174 — neuroscience — Posted on 2020-03-03
4015 Charge-Altering Releasable Transporters enable specific phenotypic manipulation of resting primary natural killer cells
Wilk, A. J.; Benner, N. L.; Vergara, R.; Haabeth, O. A. W.; Levy, R.; Waymouth, R. M.; Wender, P. A.; Blish, C. A.
10.1101/2020.02.28.970491 — immunology — Posted on 2020-03-03
4018 Genes and pathways implicated in tetralogy of Fallot revealed by ultra-rare variant burden analysis in 231 genome sequences
Manshaei, R.; Merico, D.; Reuter, M. S.; Engchuan, W.; Mojarad, B. A.; Chaturvedi, R.; Heung, T.; Pellecchia, G.; Zarrei, M.; Nalpathamkalam, T.; Khan, R.; Okello, J. B. A.; Liston, E.; Curtis, M.; Yuen, R. K. C.; Marshall, C. R.; Jobling, R. K.; Scherer, S. W.; Kim, R. H.; Bassett, A. S.
10.1101/2020.03.02.972653 — genomics — Posted on 2020-03-03
4019 Endothelial cell response to Hedgehog ligands depends on their processing
Hollier, P.-L.; Chapouly, C.; Diop, A.; Guimbal, S.; Cornuault, L.; Gadeau, A.-P.; Renault, M.-A.
10.1101/2020.03.03.974444 — physiology — Posted on 2020-03-03
4021 Genomic diversity of Escherichia coli isolates from non-human primates in the Gambia
Foster-Nyarko, E.; Alikhan, N.-F.; Ravi, A.; Thilliez, G.; Thomson, N.; Cramer, J. D.; Baker, D.; Kay, G.; O'Grady, J.; Antonio, M.; PALLEN, M. J.
10.1101/2020.02.29.971309 — genomics — Posted on 2020-03-03
4022 Clinical extended-spectrum beta-lactamase antibiotic resistance plasmids have diverse transfer rates and can spread in the absence of antibiotic selection
Benz, F.; Huisman, J. S.; Bakkeren, E.; Herter, J. A.; Stadler, T.; Ackermann, M.; Diard, M.; Egli, A.; Hall, A. R.; Hardt, W.-D.; Bonhoeffer, S.
10.1101/796243 — microbiology — Posted on 2020-03-03
4023 HLA-class II specificity assessed by high-density peptide microarray interactions
Osterbye, T.; Nielsen, M.; Dudek, N. L.; Ramarathinam, S. H.; Purcell, A. W.; Schafer-Nielsen, C.; Buus, S.
10.1101/2020.02.28.969667 — immunology — Posted on 2020-03-03
4025 Within-patient evolution to piperacillin/tazobactam resistance in a clinical isolate of Escherichia coli due to IS26-mediated amplification of blaTEM-1B
Hubbard, A. T. M.; Mason, J.; Roberts, P.; Parry, C. M.; Corless, C. E.; van Aartsen, J.; Howard, A.; Fraser, A. J.; Adams, E. R.; Roberts, A. P.; Edwards, T.
10.1101/2020.02.28.969360 — microbiology — Posted on 2020-03-03
4026 Base-pairing requirements for small RNA-mediated gene silencing of recessive self-incompatibility alleles in Arabidopsis halleri.
Burghgraeve, N.; Simon, S.; Barral, S.; Fobis-Loisy, I.; Holl, A.-C.; Ponitzki, C.; Schmitt, E.; Vekemans, X.; Castric, V.
10.1101/370239 — genetics — Posted on 2020-03-03
4029 Structural and functional characterization of the Severe fever with thrombocytopenia syndrome virus L protein
Vogel, D.; Thorkelsson, S. R.; Quemin, E. R. J.; Meier, K.; Kouba, T.; Gogrefe, N.; Busch, C.; Reindl, S.; Guenther, S.; Cusack, S.; Gruenewald, K.; Rosenthal, M.
10.1101/2020.03.02.973065 — biochemistry — Posted on 2020-03-03
4030 Exifone is a Potent HDAC1 Activator with Neuroprotective Activity in Human Neuronal Models of Neurodegeneration
Patnaik, D.; Pao, P.-C.; Zhao, W.-N.; Silva, M. C.; Hylton, N. K.; Chindavong, P. S.; Pan, L.; Tsai, L.-H.; Haggarty, S. J.
10.1101/2020.03.02.973636 — biochemistry — Posted on 2020-03-03
4032 Combined analysis of single cell RNA-Seq and ATAC-Seq data reveals regulatory toggles operating in native and iPS-derived retina.
Georges, A.; Takeda, H.; Lavergne, A.; Mandai, M.; Lepiemme, F.; Karim, L.; Demeulenaere, L.; Schyns, M.; Nguyen, L.; Rakic, J.-M.; Takahashi, M.; Georges, M.
10.1101/2020.03.02.972497 — developmental biology — Posted on 2020-03-03
4033 A single-cell analysis of the molecular lineage of chordate embryogenesis
Zhang, T.; Xu, Y.; Imai, K.; Fei, T.; Wang, G.; Dong, B.; Yu, T.; Satou, Y.; Shi, W.; Bao, Z.
10.1101/2020.03.02.966440 — developmental biology — Posted on 2020-03-03
4034 Adipose-tissue derived signals control bone remodelling.
Fu, H.; Madel, M.-B.; Pierroz, D.; Schiffrin, M.; Winkler, C.; Wilson, A.; Pochon, C.; Toffoli, B.; Jouzeau, J.-Y.; Gilardi, F.; Ferrari, S.; Bonnet, N.; BLIN-WAKKACH, C.; Desvergne, B.; MOULIN, D.
10.1101/2020.03.02.972711 — cell biology — Posted on 2020-03-03
4035 Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA
Wang, K.; Lin, R.-Z.; Hong, X.; Ng, A.; Lee, C.-N.; Neumeyer, J.; Wang, G.; Wang, X.; Ma, M.; Pu, W.; Church, G.; Melero-Martin, J.
10.1101/2020.03.02.973289 — cell biology — Posted on 2020-03-03
4038 Stress-induced tyrosine phosphorylation of RtcB modulates IRE1 activity and signaling outputs.
Papaioannou, A.; Metais, A.; Maurel, M.; Negroni, L.; Gonzales-Quiroz, M.; Zare Golchesmeh, E.; Blondel, A.; Koong, A. C.; Hetz, C.; Pedeux, R.; Tremblay, M. L.; Eriksson, L. A.; chevet, e.
10.1101/2020.03.02.972950 — biochemistry — Posted on 2020-03-03
4039 Characterization of interstitial heterogeneity in the developing kidney
Fessler, A. R.; Chaney, C. P.; Das, A.; Patel, M.; Malewsak, A.; Armendariz, D.; Hon, G.; Strand, D.; Drake, K.; Carroll, T. J.
10.1101/2020.03.02.973966 — developmental biology — Posted on 2020-03-03
4041 Time-controlled Multichannel Dynamic Traction Imaging of Biaxially Stretched Adherent Cells
Horvath, A. N.; Ziegler, A. A.; Gerhard, S.; Holenstein, C. N.; Beyeler, B.; Snedeker, J. G.; Silvan, U.
10.1101/2020.03.02.972919 — cell biology — Posted on 2020-03-03
4044 Bulk-surface coupling reconciles Min-protein pattern formation in vitro and in vivo
Brauns, F.; Pawlik, G.; Halatek, J.; Kerssemakers, J. W. J.; Frey, E.; Dekker, C.
10.1101/2020.03.01.971952 — biophysics — Posted on 2020-03-03
4045 Differential tissue stiffness of body column facilitates locomotion of Hydra on solid substrates
Naik, S.; Unni, M. K.; Sinha, D.; Rajput, S. S.; Puli, C. R.; Chatterji, A.; Patil, S.; Galande, S.
10.1101/2020.02.29.971044 — biophysics — Posted on 2020-03-03
4047 Genomic re-assessment of the transposable element landscape of the potato genome
Zavallo, D.; Crescente, J. M.; Gantuz, M.; Leone, M.; Vanzetti, L.; Masuelli, R.; Asurmendi, S.
10.1101/701888 — plant biology — Posted on 2020-03-02
4048 Citric Acid water as an alternative to water scheduling in behaving mice
Urai, A. E.; Aguillon-Rodriguez, V.; Laranjeira, I.; Cazettes, F.; The International Brain Laboratory, ; Mainen, Z. F.; Churchland, A. K.
10.1101/2020.03.02.973016 — neuroscience — Posted on 2020-03-02
4049 CALCIUM-BINDING PROTEINS ARE ALTERED IN THE CEREBELLUM IN SCHIZOPHRENIA
Vidal-Domenech, F.; Riquelme, G.; Pinacho, R.; Rodriguez-Mias, R.; Vera, A.; Monje, A.; Ferrer, I.; Callado, L. F.; Meana, J. J.; Villen, J.; Ramos, B.
10.1101/2020.03.02.972810 — neuroscience — Posted on 2020-03-02
4054 HLA-class II specificity assessed by high-density peptide microarray interactions
Osterbye, T.; Nielsen, M.; Dudek, N. L.; Ramarathinam, S. H.; Purcell, A. W.; Schafer-Nielsen, C.; Buus, S.
10.1101/2020.02.28.969667 — immunology — Posted on 2020-03-02
4062 Shark movements in the Revillagigedo Archipelago and connectivity with the Eastern Tropical Pacific
Lara Lizardi, F.; Hoyos-Padilla, M.; Hearn, A.; Klimley, A. P.; Galvan-Magana, F.; Arauz, R.; Bessudo, S.; Castro, E.; Clua, E.; Espinoza, E.; Fischer, C.; Penaherrera-Palma, C.; Steiner, T.; Ketchum, J. T.
10.1101/2020.03.02.972844 — ecology — Posted on 2020-03-02
4067 Global Motion Detection and Censoring in High-Density Diffuse Optical Tomography
Sherafati, A.; Snyder, A. Z.; Eggebrecht, A. T.; Bergonzi, K. M.; Burns-Yocum, T. M.; Lugar, H. M.; Ferradal, S. L.; Robichaux-Viehoever, A.; Smyser, C. D.; Palanca, B. J.; Hershey, T.; Culver, J. P.
10.1101/2020.02.22.961219 — neuroscience — Posted on 2020-03-02
4069 In Arabidopsis, low blue light enhances phototropism by releasing cryptochrome 1-mediated inhibition of PIF4 expression
Fankhauser, C.; Boccaccini, A.; Martina, L.; Johanna, K.; Allenbach Petrolati, L.; Goyal, A.; Ampudia, C. G.; Vernoux, T.; Karayekov, E.; Casal, J. J.
10.1101/2020.02.28.969725 — plant biology — Posted on 2020-03-02
4071 Greater male than female variability in regional brain structure across the lifespan
Wierenga, L. M.; Doucet, G. E.; Dima, D.; Agartz, I.; Aghajani, M.; Akudjedu, T. N.; Albajes-Eizagirre, A.; Alnaes, D.; Alpert, K. I.; Andreassen, O. A.; Anticevic, A.; Asherson, P.; Banaschewski, T.; Bargallo, N.; Baumeister, S.; Baur-Streubel, R.; Bertolino, A.; Bonvino, A.; Boomsma, D. I.; Borgwardt, S.; Bourque, J.; den Braber, A.; Brandeis, D.; Breier, A.; Brodaty, H.; Brouwer, R. M.; Busatto, G. F.; Calhoun, V. D.; Canales-Rodriguez, E. J.; Cannon, D.; Caseras, X.; Chaim-Avancini, T.; Ching, C. R.; Conrod, P. J.; Conzelmann, A.; Crivello, F.; Davey, C. G.; Dickie, E. W.; Ehrlich, S.; van
10.1101/2020.02.17.952010 — neuroscience — Posted on 2020-03-02
4073 Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates
Cottrell, C. A.; van Schooten, J.; Bowman, C. A.; Yuan, M.; Oyen, D.; Shin, M.; Morpurgo, R.; van der Woude, P.; van Breemen, M.; Torres, J. L.; Patel, R.; Gross, J.; Sewall, L. M.; Copps, J.; Ozorowski, G.; Nogal, B.; Sok, D.; Rakasz, E. G.; Labranche, C.; Vigdorovich, V.; Christley, S.; Carnathan, D. G.; Sather, D. N.; Montefiori, D.; Silvestri, G.; Burton, D.; Moore, J. P.; Wilson, I. A.; Sanders, R. W.; Ward, A. B.; van Gils, M. J.
10.1101/2020.02.05.936096 — immunology — Posted on 2020-03-02
4075 Reciprocal transplant experiment reveals resolution dependent partial functional redundancy in aquatic microbiome
Tandon, K.; Wan, M.-T.; Yang, C.-C.; Yang, S.-H.; Baatar, B.; Chiu, C.-Y.; Tsai, J.-W.; Liu, W.-C.; Ng, C. S.; Tang, S.-L.
10.1101/2020.02.01.930198 — ecology — Posted on 2020-03-02
4078 E-TAN, a technology-enhanced platform with tangible objects for the assessment of visual neglect: a multiple single-case study
Cerrato, A.; Pacella, D.; Palumbo, F.; Beauvais, D.; Ponticorvo, M.; Miglino, O.; Bartolomeo, P.
10.1101/849505 — neuroscience — Posted on 2020-03-02
4079 Early-life social experience shapes social avoidance reactions in larval zebrafish
Groneberg, A. H.; Marques, J. C.; Martins, A. L.; de Polavieja, G. G.; Orger, M. B.
10.1101/2020.03.02.972612 — neuroscience — Posted on 2020-03-02
4083 Toxin-antitoxin gene pairs found in Tn3family transposons appear to be an integral part of the transposition module
Lima-Mendez, G.; Oliveira Alvarenga, D.; Ross, K.; Hallet, B. G.; Van Melderen, L.; Varani, A. M.; Chandler, M.
10.1101/848275 — microbiology — Posted on 2020-03-02
4084 CRISPR-based surveillance for COVID-19 using genomically-comprehensive machine learning design
Metsky, H. C.; Freije, C. A.; Kosoko-Thoroddsen, T.-S. F.; Sabeti, P. C.; Myhrvold, C.
10.1101/2020.02.26.967026 — genomics — Posted on 2020-03-02
4085 Genome-wide study identifies association between HLA-B*55:01 and penicillin allergy
Krebs, K.; Bovijn, J.; Lepamets, M.; Censin, J. C.; Jurgenson, T.; Sarg, D.; Luo, Y.; Skotte, L.; Geller, F.; Feenstra, B.; Wang, W.; Auton, A.; 23andMe Research Team, ; Raychaudhuri, S.; Esko, T.; Metspalu, A.; Laur, S.; Holmes, M. V.; Lindgren, C. M.; Magi, R.; Milani, L.; Fadista, J.
10.1101/2020.02.27.967497 — genetics — Posted on 2020-03-02
4087 A systematic, label-free method for identifying RNA-associated proteins in vivo provides insights into vertebrate ciliary beating
Drew, K.; Lee, C.; Cox, R. M.; Dang, V.; Devitt, C. C.; Papoulas, O.; Huizar, R. L.; Marcotte, E. M.; Wallingford, J. B.
10.1101/2020.02.26.966754 — developmental biology — Posted on 2020-03-02
4091 Design of multi epitope-based peptide vaccine against E protein of human COVID-19: An immunoinformatics approach
Abdelmageed, M. I.; Abdelmoneim, A. H.; Mustafa, M. I.; Elfadol, N. M.; Murshed, N. S.; Shantier, S. W.; Makhawi, A. M.
10.1101/2020.02.04.934232 — bioinformatics — Posted on 2020-03-02
4094 Antidepressants bind to cholesterol-interaction motif of TRKB neurotrophin receptor
Casarotto, P. C.; Girych, M.; Fred, S. M.; Moliner, R.; Enkavi, G.; Biojone, C.; Cannarozzo, C.; Brunello, C.; Winkel, F.; Steinzeig, A.; Patil, S.; Vestrig, S.; Serchov, T.; Kovaleva, V.; Diniz, C. R.; Laukkanen, L.; Cardon, I.; Antila, H.; Rog, T.; Saarma, M.; Bramham, C.; Normann, C.; Lauri, S.; Vattulainen, I.; Castren, E.
10.1101/757989 — neuroscience — Posted on 2020-03-02
4097 Assessment of Brain Glucose Metabolism Following Cardiac Arrest by FDG Positron Emission Tomography
Zhang, H. J.; Mitchell, S.; Fang, Y.-H.; Tsai, H.-M.; Piao, L.; Ousta, A.; Leoni, L.; Chen, C.-T.; Sharp, W. W.
10.1101/2020.01.08.899252 — neuroscience — Posted on 2020-03-02
4098 Microglia-to-astrocyte communication modulates synaptic and cerebrovascular functions following traumatic brain injury
Rosa, J. M.; Farre-Alins, V.; Navarrete, M.; Palomino-Antolin, A.; Fernandez-Lopez, E.; Narros-Fernandez, P.; Egea, J.
10.1101/2020.03.01.972158 — neuroscience — Posted on 2020-03-02
4099 Transcript expression-aware annotation improves rare variant discovery and interpretation
Cummings, B. B.; Karczewski, K. J.; Kosmicki, J. A.; Seaby, E. G.; Watts, N. A.; Singer-Berk, M.; Mudge, J. M.; Karjalainen, J.; Satterstrom, K. F.; ODonnell-Luria, A.; Poterba, T.; Seed, C.; Solomonson, M.; Alfoldi, J.; The Genome Aggregation Database Production Team, ; The Genome Aggregation Database Consortium, ; Daly, M. J.; MacArthur, D. G.
10.1101/554444 — genomics — Posted on 2020-03-02
4100 The K-Cl co-transporter 2 is a point of convergence for multiple autism spectrum disorder and epilepsy risk gene products.
Smalley, J. L.; Kontou, G.; Choi, C.; Ren, Q.; Albrecht, D.; Abiraman, K.; Rodriguez Santos, M. A.; Bope, C. E.; Deeb, T. Z.; Davies, P. A.; Brandon, N. J.; Moss, S. J.
10.1101/2020.03.02.973859 — neuroscience — Posted on 2020-03-02
4102 Internal state configures olfactory behavior and early sensory processing in Drosophila larva
Vogt, K.; Zimmerman, D.; Schlichting, M.; Hernandez Nunez, L. A.; Qin, S.; Malacon, K.; Rosbash, M.; Pehlevan, C.; Cardona, A.; Samuel, A.
10.1101/2020.03.02.973941 — neuroscience — Posted on 2020-03-02
4103 Spatiotemporal patterns of neocortical activity around hippocampal sharp-wave ripples
Karimi Abadchi, J.; Nazari-Ahangarkolaee, M.; Gattas, S.; Bermudez-Contreras, E.; Luczak, A.; McNaughton, B. L.; Mohajerani, M. H.
10.1101/787218 — neuroscience — Posted on 2020-03-02
4105 Minimally invasive classification of pediatric solid tumors using reduced representation bisulfite sequencing of cell-free DNA: a proof-of-principle study
Van Paemel, R.; De Koker, A.; Vandeputte, C.; van Zogchel, L.; Lammens, T.; Laureys, G.; Vandesompele, J.; Schleiermacher, G.; Chicard, M.; Van Roy, N.; Vicha, A.; Tytgat, G. A. M.; Callewaert, N.; De Preter, K.; De Wilde, B.
10.1101/795047 — genomics — Posted on 2020-03-02
4106 Dynamics of the 4D genome during lineage specification, differentiation and maturation in vivo
Oudelaar, A. M.; Beagrie, R. A.; Gosden, M.; De Ornellas, S.; Georgiades, E.; Kerry, J.; Hidalgo, D.; Carrelha, J.; Shivalingam, A.; El-Sagheer, A. H.; Telenius, J. M.; Brown, T.; Buckle, V. J.; Socolovsky, M.; Higgs, D. R.; Hughes, J. R.
10.1101/763763 — genomics — Posted on 2020-03-02
4107 Profiles of circulating histidine-rich glycoprotein associate with chronological age and risk of all-cause mortality
Hong, M.-G.; Dodig-Crnkovic, T.; Chen, X.; Drobin, K.; Lee, W.; Wang, Y.; Edfors, F.; Kotol, D.; Thomas, C. E.; Sjöberg, R.; Odeberg, J.; Hamsten, A.; Silveira, A.; Hall, P.; Nilsson, P.; Pawitan, Y.; Hägg, S.; Uhlen, M.; Pedersen, N. L.; Magnusson, P. K. E.; Schwenk, J. M.
10.1101/464909 — epidemiology — Posted on 2020-03-02
4109 Information and communication technology, mobile devices, and medical education
Rodriguez Rio, A.; Espinoza Tellez, G.; Martinez-Ezquerro, J. D.; Rendon-Macias, M. E.
10.1101/420281 — scientific communication and education — Posted on 2020-03-02
4111 KSHV lytic mRNA is efficiently translated in the absence of eIF4F
Pringle, E. S.; Robinson, C.-A.; Crapoulet, N.; Monjo, A. L.-A.; Bouzanis, K.; Leidal, A. M.; Lewis, S. M.; Gaston, D.; Uniacke, J.; McCormick, C.
10.1101/356162 — microbiology — Posted on 2020-03-02
4112 Uncyclized xanthommatin is a key ommochrome intermediate in invertebrate coloration
Figon, F.; Munsch, T.; Croix, C.; Viaud-Massuard, M.-C.; Lanoue, A.; Casas, J.
10.1101/666529 — biochemistry — Posted on 2020-03-02
4113 Identification of Adomavirus Virion Proteins
Welch, N. L.; Tisza, M. J.; Starrett, G. J.; Belford, A. K.; Pastrana, D. V.; Pang, Y.-Y. S.; Schiller, J. T.; An, P.; Cantalupo, P. G.; Pipas, J. M.; Koda, S.; Subramaniam, K.; Waltzek, T. B.; Bian, C.; Shi, Q.; Ruan, Z.; Ng, T. F. F.; Buck, C. B.
10.1101/341131 — microbiology — Posted on 2020-03-02
4114 The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding.
Mycroft-West, C. J.; Su, D.; Elli, S.; Guimond, S. E.; Miller, G. J.; Turnbull, J. E.; Yates, E. A.; Guerrini, M.; Fernig, D. G.; Andrade de Lima, M.; Skidmore, M. A.
10.1101/2020.02.29.971093 — biochemistry — Posted on 2020-03-02
4116 Structural basis of transcription-translation coupling and collision in bacteria.
Webster, M. W.; Takacs, M.; Zhu, C.; Vidmar, V.; Eduljee, A. D.; Abdelkareem, M.; Weixlbaumer, A.
10.1101/2020.03.01.971028 — biochemistry — Posted on 2020-03-02
4117 Origin of photosynthetic water oxidation at the dawn of life
Oliver, T.; Sanchez-Baracaldo, P.; Larkum, A. W.; Rutherford, A. W.; Cardona, T.
10.1101/2020.02.28.969766 — evolutionary biology — Posted on 2020-03-02
4119 Voluntary running does not increase capillary blood flow but promotes neurogenesis and short-term memory in the APP/PS1 mouse model of Alzheimers disease
Falkenhain, K.; Ruiz-Uribe, N. E.; Haft-Javaherian, M.; Ali, M.; contributor, S. C.; Michelucci, P. E.; Schaffer, C. B.; Bracko, O.
10.1101/2020.02.28.969840 — neuroscience — Posted on 2020-03-02
4121 Macrophage scavenger receptor 1 controls Chikungunya virus infection through autophagy
Yang, L.; Geng, T.; Yang, G.; Ma, J.; Wang, L.; Ketkar, H.; Yang, D.; Lin, T.; Hwang, J.; Zhu, S.; Wang, Y.; Dai, J.; You, F.; Cheng, G.; Vella, A.; Flavell, R. A.; Fikrig, E.; WANG, P.
10.1101/2020.02.28.969832 — microbiology — Posted on 2020-03-02
4123 Non-redundant roles of caspase-4 and caspase-5 in heme driven- IL-1β release and cell death
Bolivar, B. E.; Rohrman, B. A.; Charendoff, C. I.; Yazdani, V.; Belcher, J. D.; Vercellotti, G. M.; Flanagan, J. M.; Bouchier-Hayes, L.
10.1101/2020.02.28.969899 — immunology — Posted on 2020-03-02
4124 A haplotype-resolved, de novo genome assembly for the wood tiger moth (Arctia plantaginis) through trio binning
Yen, E. C.; McCarthy, S. A.; Galarza, J. A.; Generalovic, T. N.; Pelan, S.; Nguyen, P.; Meier, J. I.; Warren, I. A.; Mappes, J.; Durbin, R.; Jiggins, C. D.
10.1101/2020.02.28.970020 — genomics — Posted on 2020-03-02
4127 Vorpal: A Novel RNA Virus Feature-Extraction Algorithm Demonstrated Through Interpretable Genotype-to-Phenotype Linear Models
Davis, P.; Bagnoli, J.; Yarmosh, D.; Shteyman, A.; Presser, L.; Altmann, S.; Bradrick, S.; Russell, J. A.
10.1101/2020.02.28.969782 — bioinformatics — Posted on 2020-03-02
4131 Chromosome-Scale Genome Assembly Provides Insights into Speciation of Allotetraploid and Massive Biomass Accumulation of Elephant Grass (Pennisetum purpureum Schum.)
Zhang, S.; Xia, Z.; Zhang, W.; Li, C.; Wang, X.; Lu, X.; Zhao, X.; Ma, H.; Zhang, W.; Zhou, X.; Zhu, T.; Liu, P.; Liu, G.; Yang, H.; Arango, J.; Peters, M.; Wang, W.; Xia, T.
10.1101/2020.02.28.970749 — genomics — Posted on 2020-03-02
4132 Targeted high-resolution chromosome conformation capture at genome-wide scale.
Downes, D.; Gosden, M. E.; Telenius, J.; Carpenter, S. J.; Nussbaum, L.; De Ornellas, S.; Sergeant, M.; Eijsbouts, C. Q.; Schwessinger, R.; Kerry, J.; Roberts, N.; Shivalingam, A.; El-Sagheer, A.; Oudelaar, A. M.; Brown, T.; Buckle, V. J.; Davies, J. O. J.; Hughes, J. R.
10.1101/2020.03.02.953745 — genomics — Posted on 2020-03-02
4133 Switching secretory pathway direction for organelle acquisition in plants
Kanazawa, T.; Morinaka, H.; Ebine, K.; Shimada, T. L.; Ishida, S.; Minamino, N.; Yamaguchi, K.; Shigenobu, S.; Kohchi, T.; Nakano, A.; Ueda, T.
10.1101/2020.03.02.956961 — plant biology — Posted on 2020-03-02
4134 TipQAD: an automated tool for quantifying apical fluorescence dynamics in tip-growing cells
Tambo, A. L.; Bhanu, B.; Luo, N.; Rong, D.; Wang, F.; Craddock, C.; Lavagi, I.; Yang, Z.
10.1101/2020.03.01.960591 — plant biology — Posted on 2020-03-02
4135 Drivers of large-scale spatial demographic variation in a perennial plant
Roemer, G.; Christiansen, D. M.; de Buhr, H.; Hylander, K.; Jones, O. R.; Merinero, S.; Reitzel, K.; Ehrlen, J.; Dahlgren, J.
10.1101/2020.02.29.969428 — plant biology — Posted on 2020-03-02
4136 Temporal learning among prefrontal and striatal ensembles
Emmons, E. B.; Chiuffa Tunes, G.; Choi, J.; Bruce, R. A.; Weber, M.; Kim, Y.; Narayanan, N.
10.1101/2020.02.28.970053 — neuroscience — Posted on 2020-03-02
4138 Diversification of molecularly defined myenteric neuron classes revealed by single cell RNA-sequencing
Morarach, K.; Mikhailova, A.; Knoflach, V.; Memic, F.; Kumar, R.; Li, W.; Ernfors, P.; Marklund, U.
10.1101/2020.03.02.955757 — neuroscience — Posted on 2020-03-02
4139 An integrated transcriptomic and epigenomic atlas of mouse primary motor cortex cell types
Yao, Z.; Liu, H.; Xie, F.; Fischer, S.; Adkins, R. S.; Aldrige, A. I.; Ament, S. A.; Bartlett, A.; Behrens, M. M.; Van den Berge, K.; Bertagnolli, D.; Biancalani, T.; Booeshaghi, A. S.; Corrada Bravo, H.; Casper, T.; Colantuoni, C.; Crabtree, J.; Creasy, H.; Crichton, K.; Crow, M.; Dee, N.; Dougherty, E. L.; Doyle, W. I.; Dudoit, S.; Fang, R.; Felix, V.; Fong, O.; Giglio, M.; Goldy, J.; Hawrylycz, M.; Bezieux, H. R. d.; Herb, B. R.; Hertzano, R.; Hou, X.; Hu, Q.; Huang, Z. J.; Kancherla, J.; Kroll, M.; Lathia, K.; Li, Y. E.; Lucero, J. D.; Luo, C.; Mahurkar, A.; McMillen, D.; Nadaf, N. M.; Ner
10.1101/2020.02.29.970558 — neuroscience — Posted on 2020-03-02
4145 Vitamin D receptor and STAT3 cooperate to establish TET2-mediated tolerogenesis
Catala-Moll, F.; Li, T.; Ciudad, L.; Rodriguez-Ubreva, J.; Ballestar, E.
10.1101/2020.02.28.969634 — immunology — Posted on 2020-03-02
4146 The genomic landscapes of individual melanocytes from human skin
Tang, J.; Fewings, E.; Chang, D.; Zeng, H.; Liu, S.; Jorapur, A.; Belote, R.; McNeal, A.; Yeh, I.; Arron, S. T.; Judson-Torres, R. L.; Bastian, B. C.; Shain, A. H.
10.1101/2020.03.01.971820 — genomics — Posted on 2020-03-02
4147 Gene-environment interactions in Multiple Sclerosis: a UK Biobank study
Jacobs, B. M.; Noyce, A.; Bestwick, J. P.; Belete, D.; Giovannoni, G.; Dobson, R.
10.1101/2020.03.01.971739 — genetics — Posted on 2020-03-02
4154 Structural attributes and principles of the neocortical connectome in the marmoset monkey
Theodoni, P.; Majka, P.; Reser, D. H.; Wojcik, D. K.; Rosa, M. G. P.; Wang, X.-J.
10.1101/2020.02.28.969824 — neuroscience — Posted on 2020-03-02
4155 Validation of melomind(TM) signal quality: a proof of concept resting-state and ERPs study
Spinelli, G.; Odouard, A.; Nierat, M.-C.; Campion, S.; Bensoussan, M.; Grosselin, F.; Pandremmenou, K.; Breton, A.; Raux, M.; Attal, Y.; Similowski, T.; Navarro-Sune, X.
10.1101/2020.02.28.969808 — neuroscience — Posted on 2020-03-02
4156 Genomic diversity of Escherichia coli isolates from non-human primates in the Gambia
Foster-Nyarko, E.; Alikhan, N.-F. J.; Ravi, A.; Thilliez, G.; Thomson, N.; Cramer, J. D.; Baker, D.; Kay, G.; O'Grady, J.; Antonio, M.; PALLEN, M. J.
10.1101/2020.02.29.971309 — genomics — Posted on 2020-03-02
4160 Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors
Graves, A. R.; Roth, R.; Tan, H.; Zhu, Q.; Bygrave, A.; Lopez-Ortega, E.; Spiegel, A.; Hong, I.; Johnson, R.; Vogelstein, J.; Tward, D.; Miller, M.; Huganir, R. L.
10.1101/2020.03.01.972216 — neuroscience — Posted on 2020-03-02
4161 Structural basis of transcription-translation coupling
Wang, C.; Molodtsov, V.; Firlar, E.; Kaelber, J.; Blaha, G.; Su, M.; Ebright, R. H.
10.1101/2020.03.01.972380 — molecular biology — Posted on 2020-03-02
4162 Somatic cell-derived BMPs induce male germ cell meiosis initiation during embryonic stage via regulating Dazl expression
Gao, F.; Zhang, L.; Li, Y.; Hu, Y.; Lin, L.; Zhou, J.; Chen, M.; Qin, Y.; Zhou, Y.; Chen, M.; Cui, X.; Tang, F.
10.1101/2020.03.01.971937 — developmental biology — Posted on 2020-03-02
4163 Expression of the endocannabinoid system in the human airway epithelial cells: Impact of sex and chronic respiratory disease status
Fantauzzi, M. F.; Aguiar, J. A.; Tremblay, B. J.-M.; Yanagihara, T.; Chandiramohan, A.; Revill, S.; Ryu, M. H.; Carlsten, C.; Ask, K.; Stampfli, M.; Doxey, A. C.; Hirota, J. A.
10.1101/2020.03.01.971960 — cell biology — Posted on 2020-03-02
4175 Kallikrein 13: a new player in coronaviral infections.
Milewska, A.; Falkowski, K.; Kalinska, M.; Bielecka, E.; Naskalska, A.; Mak, P.; Lesner, A.; Ochman, M.; Urlik, M.; Potempa, J.; Kantyka, T.; Pyrc, K.
10.1101/2020.03.01.971499 — microbiology — Posted on 2020-03-02
4178 Mutations, Recombination and Insertion in the Evolution of 2019-nCoV
Wu, A.; Niu, P.; Wang, L.; Zhou, H.; Zhao, X.; Wang, W.; Wang, J.; Ji, C.; Ding, X.; Wang, X.; Lu, R.; Gold, S.; Aliyari, S.; Zhang, S.; Vikram, E.; Zou, A.; Lenh, E.; Chen, J.; Ye, F.; Han, N.; Peng, Y.; Guo, H.; Wu, G.; Jiang, T.; Tan, W.; Cheng, G.
10.1101/2020.02.29.971101 — microbiology — Posted on 2020-03-02
4180 Optimal tuning of weighted kNN- and diffusion-based methods for denoising single cell genomics data
Tjaernberg, A.; Mahmood, O.; Jackson, C. A.; Saldi, G.-A.; Cho, K.; Christiaen, L.; Bonneau, R.
10.1101/2020.02.28.970202 — bioinformatics — Posted on 2020-03-02
4182 CRISPR-based COVID-19 surveillance using a genomically-comprehensive machine learning approach
Metsky, H. C.; Freije, C. A.; Kosoko-Thoroddsen, T.-S. F.; Sabeti, P. C.; Myhrvold, C.
10.1101/2020.02.26.967026 — genomics — Posted on 2020-03-02
4183 Screening of FDA-approved drugs using a MERS-CoV clinical isolate from South Korea identifies potential therapeutic options for COVID-19
Ko, M.; Chang, S. Y.; Byun, S. Y.; Choi, I.; d'Alexandry d'Orengiani, A. L. P. H.; Shum, D.; Min, J.-Y.; Windisch, M. P.
10.1101/2020.02.25.965582 — microbiology — Posted on 2020-03-02
4186 Post-Transcriptional Circadian Regulation in Macrophages Organizes Temporally Distinct Immunometabolic States
Collins, E. J.; Cervantes-Silva, M. P.; Timmons, G. A.; O'Siorain, J. R.; Curtis, A. M.; Hurley, J. M.
10.1101/2020.02.28.970715 — molecular biology — Posted on 2020-03-02
4191 AtCIPK16 Mediates Salt Stress Through Phytohormones and Transcription Factors
Amarasinghe, S. L.; Huang, W.; Watson-Haigh, N. S.; Gilliham, M.; Roy, S. J.; Baumann, U.
10.1101/2020.02.17.953216 — plant biology — Posted on 2020-03-01
4192 Artificial diets modulate infection rates of Nosema ceranae in bumblebees
Gomez-Moracho, T.; Durand, T.; Pasquaretta, C.; Heeb, P.; Lihoreau, M.
10.1101/2020.02.27.967455 — physiology — Posted on 2020-03-01
4193 Dissociable roles of central striatum and anterior lateral motor area in initiating and sustaining naturalistic behavior
Corbit, V.; Piantadosi, S. C.; Wood, J. T.; Liu, G.; Choi, C. J. Y.; Witten, I.; Gittis, A. H.; Ahmari, S. E.
10.1101/2020.01.08.899070 — neuroscience — Posted on 2020-03-01
4200 Proteome-wide Prediction of Lysine Methylation Reveals Novel Histone Marks and Outlines the Methyllysine Proteome
Biggar, K. K.; Charih, F.; Liu, H.; Ruiz-Blanco, Y. B.; Stalker, L.; Chopra, A.; Connolly, J.; Adhikary, H.; Frensemier, K.; Galka, M.; Fang, Q.; Wynder, C.; Standford, W.; Green, J. R.; Li, S. S. C.
10.1101/274688 — biochemistry — Posted on 2020-03-01
4201 Tumor heterogeneity assessed by sequencing and fluorescence in situ hybridization (FISH) data
Lei, H.; Gertz, E. M.; Schäffer, A. A.; Fu, X.; Tao, Y.; Heselmeyer-Haddad, K.; Torres, I.; Shi, X.; Wu, K.; LI, G.; Xu, L.; Hou, Y.; Dean, M.; Ried, T.; Schwartz, R.
10.1101/2020.02.29.970392 — bioinformatics — Posted on 2020-03-01
4203 Yolk sac erythromyeloid progenitors sustain erythropoiesis throughout embryonic life
Soares-da-Silva, F.; Burlen-Defranoux, O.; Elsaid, R.; Iturri, L.; Freyer, L.; Sismeiro, O.; Pinto-do-O, P.; Gomez-Perdiguero, E.; Cumano, A.
10.1101/2020.02.27.968230 — developmental biology — Posted on 2020-03-01
4204 Manganese complex Br increases antibiotic sensitivity in multidrug resistant Streptococcus pneumoniae
Liakopoulos, A.; LaRagione, R.; Nagel, C.; Schatzschneider, U.; Rozen, D.; Betts, J. W.
10.1101/2020.02.27.969048 — microbiology — Posted on 2020-03-01