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Archive, 2022-10

3 Excitatory amino acid transporter 1 supports adult hippocampal neural stem cell self-renewal.
Rieskamp, J. D.; Rosado-Burgos, I.; Christofi, J. E.; Ansar, E.; Einstein, D.; Walters, A. E.; Valentini, V.; Bruno, J. P.; Kirby, E. D.
10.1101/2022.10.31.514562 — neuroscience — Posted on 2022-10-31
4 Schwann cells promote sensory neuron excitability during development
Kantarci, H.; Elvira, P. D.; Thottumkara, A. P.; Iyer, M.; Donovan, L. J.; Ambiel, N.; OConnell, E. M.; Granados, A.; Zeng, H.; Saw, N. L.; Lutz, A. B.; Sloan, S. A.; Gray, E. E.; Tran, K. V.; Vichare, A.; Yeh, A. K.; Munch, A. E.; Huber, M.; Agrawal, A.; Morri, M.; Shamloo, M.; Tawfik, V. L.; Du Bois, J.; Zuchero, J. B.
10.1101/2022.10.31.514415 — neuroscience — Posted on 2022-10-31
9 Cortico-thalamo-cortical interactions modulate electrically evoked EEG responses in mice
Claar, L. D.; Rembado, I.; Kuyat, J. R.; Russo, S.; Marks, L. C.; Olsen, S. R.; Koch, C.
10.1101/2022.07.22.501195 — neuroscience — Posted on 2022-10-31
10 Evolutionary-scale prediction of atomic level protein structure with a language model
Lin, Z.; Akin, H.; Rao, R.; Hie, B.; Zhu, Z.; Lu, W.; Smetanin, N.; Verkuil, R.; Kabeli, O.; Shmueli, Y.; dos Santos Costa, A.; Fazel-Zarandi, M.; Sercu, T.; Candido, S.; Rives, A.
10.1101/2022.07.20.500902 — synthetic biology — Posted on 2022-10-31
11 Spatiotemporal orchestration of multicellular transcriptional programs and communications in the early stage of spinal cord injury
Wang, Z.; Li, Z.; Luan, T.; Cui, G.; Shu, S.; Liang, Y.; Xiao, J.; Zhang, K.; Yu, W.; Cui, J.; Li, A.; Peng, G.; Fang, Y.
10.1101/2022.10.07.511269 — neuroscience — Posted on 2022-10-31
15 Cell-free, methylated DNA in blood samples reveals tissue-specific, cellular damage from radiation treatment
Barefoot, M. E.; Loyfer, N.; Kiliti, A. J.; Schmidt, M. O.; Shabi-Porat, S.; Jain, S.; Roth, S. M.; McDeed, A. P.; Shahrour, N.; Ballew, E.; Lin, Y.-T.; Li, H.-H.; Mays, A. D.; Rudra, S.; Riegel, A. T.; Unger, K.; Kaplan, T.; Wellstein, A.
10.1101/2022.04.12.487966 — cancer biology — Posted on 2022-10-31
19 Hsp47 Promotes Biogenesis of Multi-subunit Neuroreceptors in the Endoplasmic Reticulum
Wang, Y.-J.; Di, X.-J.; Han, D.-Y.; Nashmi, R.; Henderson, B. J.; Moss, F. J.; Mu, T.-W.
10.1101/2022.10.24.513629 — cell biology — Posted on 2022-10-31
27 Towards rainy high Arctic winters: how ice-encasement impacts tundra plant phenology, productivity and reproduction
Le Moullec, M.; Hendel, A.-L.; Petit Bon, M.; Jonsdottir, I. S.; Varpe, O.; van der Wal, R.; Beumer, L.; Layton-Matthews, K.; Isaksen, K.; Hansen, B. B.
10.1101/2021.06.10.447955 — plant biology — Posted on 2022-10-31
28 WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma
Mitchell, K.; Shakya, S.; Arora, S.; Sprowls, S. A.; Silver, D. J.; Goins, C. M.; Wallace, L.; Roversi, G.; Schafer, R.; Kay, K.; Miller, T. E.; Lauko, A.; Kashyap, A.; Kass, J. D.; Mulkearns-Hubert, E. E.; Johnson, S.; Alvarado, J.; Rich, J. N.; Paddison, P. J.; Patel, A. P.; Stauffer, S. R.; Hubert, C. G.; Lathia, J. D.
10.1101/2021.09.20.461125 — cancer biology — Posted on 2022-10-31
30 PEMT: A patent enrichment tool for drug discovery
Gadiya, Y.; Zaliani, A.; Gribbon, P.; Hofmann-Apitius, M.
10.1101/2022.07.28.501730 — bioinformatics — Posted on 2022-10-31
32 Aortic Shape Space Topology
Khabaz, K.; Sankary, S.; Yuan, K.; Pugar, J.; Kim, J.; Kang, J.; Nguyen, N.; Cao, K.; Pierce, N.; Lee, C. J.; Milner, R.; Kindlmann, G.; Pocivavsek, L.
10.1101/2022.09.19.508582 — bioengineering — Posted on 2022-10-31
33 Graphene Biointerface for Cardiac Arrhythmia Diagnosis and Treatment
Lin, Z.; Kireev, D.; Liu, N.; Gupta, S.; LaPaino, J.; Obaid, S.; Chen, Z.; Akinwande, D.; Efimov, I. R.
10.1101/2022.06.28.497825 — bioengineering — Posted on 2022-10-31
36 Unraveling Amazon tree community assembly using Maximum Information Entropy: a quantitative analysis of tropical forest ecology.
Pos, E.; de Souza Coelho, L.; de Andrade Lima Filho, D.; Salomco, R. P.; Amaral, I. L.; de Almeida Matos, F. D.; Castilho, C. V.; Phillips, O. L.; Guevara, J. E.; Carim, M. d. J. V.; Lopez, D. C.; Magnusson, W. E.; Wittmann, F.; Irume, M. V.; Martins, M. P.; Sabatier, D.; da Silva Guimarces, J. R.; Molino, J.-F.; Banki, O. S.; Fernandez Piedade, M. T.; Pitman, N. C. A.; Mendoza, A. M.; Ramos, J. F.; Hawes, J. E.; Almeida, E. J.; Barbosa, L. F.; Cavalheiro, L.; Vilela dos Santos, M. C.; Luize, B. G.; Moraes de Leco Novo, E. M.; Vargas, P. N.; Freire Silva, T. S.; Venticinque, E. M.; Manzatto, A
10.1101/2021.03.31.437717 — ecology — Posted on 2022-10-31
37 High overexploitation risk due to management shortfall in highly traded requiem sharks
Sherman, C. S.; Digel, E. D.; Zubick, P.; Eged, J.; Haque, A. B.; Matsushiba, J. H.; Simpfendorfer, C. A.; Sant, G.; Dulvy, N. K.
10.1101/2022.06.09.495558 — ecology — Posted on 2022-10-31
38 One gene - two proteins: The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration.
Petragnano, F.; Fasciani, I.; Wang, Z.; Edwards, R.; Telugu, N.; Pietrantoni, I.; Zabel, U.; Zauber, H.; Grieben, M.; Terzenidou, M. E.; Di Gregorio, J.; Pellegrini, C.; Santini, S.; Taddei, A. R.; Poehl, B.; Aringhieri, S.; Carli, M.; Aloisi, G.; Marampon, F.; Roman, A.; Diecke, S.; Flati, V.; Giorgi, F.; Scarselli, M.; Tobin, A. B.; Amicarelli, F.; Tokatlidis, K.; Rossi, M.; Lohse, M. J.; Annibale, P.; Maggio, R.
10.1101/2021.04.13.438299 — cell biology — Posted on 2022-10-31
41 Reversing gut microbiome-driven adipose tissue inflammation alleviates metabolic syndrome
Newman, N. K.; Zhang, Y.; Padiadpu, J.; Miranda, C.; Magana, A. A.; Hioki, K.; Pederson, J. W.; Li, Z.; Gurung, M.; Bruce, A. M.; Brown, K.; Bobe, G.; Sharpton, T. J.; Shulzhenko, N.; Maier, C.; Stevens, J. F.; Gombart, A. F.; Morgun, A.
10.1101/2022.10.28.514267 — systems biology — Posted on 2022-10-31
46 Prefrontal allopregnanolone mediates the adverse effects of acute stress in a mouse model of tic pathophysiology
Cadeddu, R.; Van Zandt, M.; Odeh, K.; Anderson, C. J.; Flanagan, D.; Nordkild, P.; Pittenger, C. J.; Bortolato, M.
10.1101/2022.10.29.514372 — animal behavior and cognition — Posted on 2022-10-31
49 Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales
Pouzet, S.; Cruz-Ramon, J.; Le Bec, M.; Cordier, C.; Banderas, A.; Barral, S.; Sorre, B.; Castano-Cerezo, S.; Lautier, T.; Truan, G.; Hersen, P.
10.1101/2022.10.31.514479 — synthetic biology — Posted on 2022-10-31
50 TRPV1-mediated sonogenetic neuromodulation of motor cortex in freely moving mice
Xu, K.; Yang, Y.; Hu, Z.; Yue, Y.; Cui, J.; Culver, J. P.; Bruchas, M. R.; Chen, H.
10.1101/2022.10.28.514307 — bioengineering — Posted on 2022-10-31
52 Internal Validation of the ForenSeq Kintelligence Kit for Application to Forensic Genetic Genealogy
Peck, M. A.; Koeppel, A. F.; Gorden, E. M.; Bouchet, J.; Heaton, M. C.; Russell, D. A.; Reedy, C. R.; Neal, C. M.; Turner, S. D.
10.1101/2022.10.28.514056 — genomics — Posted on 2022-10-31
54 The power of geohistorical boundaries for modeling the genetic background of human populations: the case of the rural Catalan Pyrenees
Fibla, J.; Maceda, I.; Laplana, M.; Guerrero, M.; Alvarez, M. M.; Burgueno, J.; Camps, A.; Fabrega, J.; Felisart, J.; Grane, J.; Remon, J. L.; Serra, J.; Moral, P.; Lao, O.
10.1101/2022.10.28.513229 — genetics — Posted on 2022-10-31
59 Augmenting TCR signal strength and ICOS costimulation results in metabolically fit and therapeutically potent human CAR Th17 cell therapy
Wyatt, M. M.; Huff, L. W.; Nelson, M. H.; Neal, L. R.; Medvec, A. R.; Rangel Rivera, G. O.; Smith, A. S.; Rivera Reyes, A. M.; Knochelmann, H. M.; Riley, J. L.; Lesinski, G. B.; Paulos, C. M.
10.1101/2022.10.28.514057 — immunology — Posted on 2022-10-31
62 Synthesis and Biological Evaluation of New Isoxazolyl Steroids as Anti-Prostate Cancer Agents
Rudovich, A. S.; Perina, M.; Krech, A. V.; Novozhilova, M. Y.; Tumilovich, A. M.; Shkel, T. V.; Grabovec, I. P.; Kvasnica, M.; Mada, L.; Zavialova, M. G.; Mekhtiev, A. R.; Jorda, R.; Zhabinskii, V. N.; Khripach, V. A.
10.1101/2022.10.28.513486 — pharmacology and toxicology — Posted on 2022-10-31
63 An Artificial Intelligence Framework for Optimal Drug Design
Ramey, G.; Vargas, S.; De Alwis, D.; Alexandrova, A. N.; Distefano, J.; Bloomingdale, P.
10.1101/2022.10.29.514379 — pharmacology and toxicology — Posted on 2022-10-31
64 Alveolar epithelial type 1 cells serve as a cell of origin for lung adenocarcinoma with distinct molecular and phenotypic presentation
Yang, M.; Shen, H.; Flodby, P.; Koss, M.; Bassiouni, R.; Liu, Y.; Jashashvilli, T.; Stueve, T. R.; Mullen, D. J.; Ryan, A. L.; Carpten, J.; Castaldi, A.; Wallace, W. D.; Zhou, B.; Borok, MD, Z.; Marconett, C. N.
10.1101/2022.10.29.514334 — cancer biology — Posted on 2022-10-31
65 Refining structural models of membrane proteins withdisordered domains in phospholipid nanodiscs
Pedersen, M. C.; Johansen, N. T.; Roche, J.; Jaarvaa, M.; Tornroth-Horsefield, S.; Arleth, L.
10.1101/2022.10.28.512841 — biophysics — Posted on 2022-10-31
66 Automated simulation-based membrane-protein refinement into cryo-EM data
Yvonnesdotter, L.; Rovsnik, U.; Blau, C.; Lycksell, M.; Howard, R. J.; Lindahl, E.
10.1101/2022.10.28.514175 — biophysics — Posted on 2022-10-31
69 Deep Learning vs Gradient Boosting in age prediction on immunology profile
Kalyakulina, A.; Yusipov, I.; Kondakova, E.; Bacalini, M. G.; Franceschi, C.; Vedunova, M.; Ivanchenko, M.
10.1101/2022.10.28.514283 — bioinformatics — Posted on 2022-10-31
70 Expanding the stdpopsim species catalog, and lessons learned forrealistic genome simulations
Lauterbur, M. E.; Cavassim, M. I. A.; Gladstein, A. L.; Gower, G.; Pope, N. S.; Tsambos, G.; Adrion, J.; Belsare, S.; Biddanda, A.; Caudill, V.; Cury, J.; Echevarria, I.; Haller, B. C.; Hasan, A. R.; Huang, X.; Iasi, L. N. M.; Noskova, E.; Obsteter, J.; Pavinato, V. A. C.; Pearson, A.; Peede, D.; Perez, M. F.; Rodrigues, M. F.; Smith, C. C. R.; Spence, J. P.; Teterina, A.; Tittes, S.; Unneberg, P.; Vazquez, J. M.; Waples, R. K.; Wohns, A. W.; Wong, Y.; Baumdicker, F.; Cartwright, R. A.; Gorjanc, G.; Gutenkunst, R. N.; Kelleher, J.; Kern, A. D.; Ragsdale, A. P.; Ralph, P. L.; Schrider, D. R.; G
10.1101/2022.10.29.514266 — bioinformatics — Posted on 2022-10-31
72 Identifying endogenous peptide receptors bycombining structure and transmembrane topologyprediction
Teufel, F.; Refsgaard, J. C.; Kasimova, M. A.; Madsen, C. T.; Stahlhut, C.; Gronborg, M.; Winther, O.; Madsen, D.
10.1101/2022.10.28.514036 — bioinformatics — Posted on 2022-10-31
73 In Silico, Brain Mesh Platform for Computing Topographic Dependent Internal Facets
Shaw, C.; Riviere-Cazaux, C.; Obrochta, D.; Otto, S.; Ray, L.; Strother, L.; Burns, T.; Khan, M. R.
10.1101/2022.10.27.514138 — bioengineering — Posted on 2022-10-31
74 Photonic-Plasmonic Coupling Enhanced Fluorescence Enabling Digital-Resolution Ultrasensitive Protein Detection
Barya, P.; Xiong, Y.; Shepherd, S.; Gupta, R.; Akin, L. D.; Tibbs, J.; Lee, H. K.; Singamaneni, S.; Cunningham, B. T.
10.1101/2022.10.29.514360 — bioengineering — Posted on 2022-10-31
76 A multi-omics analysis of glioma chemoresistance using a hybrid microphysiological model of glioblastoma
Shojaei, S.; Basso, J.; Amereh, M.; Alizadeh, J.; Dehesh, T.; Rosa, S. D. S.; Clark, C.; Hassan, M.; Tomczyk, M.; Cole, L.; Hatch, G.; Dolinsky, V.; Pasco, C.; Schibli, D.; Dhingra, S.; Srivastava, A.; Ravandi, A.; Vitorino, R.; Ghavami, S.; Akbari, M.
10.1101/2022.10.29.514383 — bioengineering — Posted on 2022-10-31
79 Genetic variants of human platelet antigens in the Indian population from 1029 whole genomes
Rophina, M.; Bhoyar, R. C.; Imran, M.; Senthivel, V.; Divakar, M. K.; Mishra, A.; Jolly, B.; Sivasubbu, S.; Scaria, V.
10.1101/2022.10.29.514338 — genomics — Posted on 2022-10-31
81 Heritability estimation of cognitive phenotypes in the ABCD Study using mixed models
Smith, D. M.; Loughnan, R. J.; Friedman, N. P.; Parekh, P.; Frei, O.; Thompson, W. K.; Andreassen, O.; Neale, M.; Jernigan, T. L.; Dale, A.
10.1101/2022.10.28.512918 — genetics — Posted on 2022-10-31
84 SUB-OPTIMAL ENVIRONMENTAL CONDITIONS PROLONG PHAGE EPIDEMICS IN BACTERIAL POPULATIONS
Goehlich, H.; Roth, O.; Sieber, M.; Chibani, C. M.; Poehlein, A.; Rajkov, J.; Liesegang, H.; Wendling, C. C.
10.1101/2022.10.28.514181 — evolutionary biology — Posted on 2022-10-31
86 Comparative Phylogenetic Analysis and Transcriptomic Profiling of Dengue (DENV-3 genotype I) Outbreak in 2021 in Bangladesh
Sarkar, M. M. H.; Rahman, M. S.; Islam, M. R.; Rahman, A.; Islam, M. S.; Banu, T. A.; Akter, S. -; Barna Goswami, B.; Jahan, I.; Habib, M. A.; Mohi Uddin, M.; Miah, M. I.; Shaikh, A. A.; Khan, M. S.
10.1101/2022.10.29.514352 — evolutionary biology — Posted on 2022-10-31
90 How density dependence, genetic erosion, and the extinction vortex impact evolutionary rescue
Nordstrom, S. W.; Hufbauer, R. A.; Olazcuaga, L.; Durkee, L. F.; Melbourne, B. A.
10.1101/2022.10.29.514126 — ecology — Posted on 2022-10-31
91 Using spatio-temporal information in weather radar data to detect and track communal bird roosts
Perez, G.; Zhao, W.; Cheng, Z.; Belotti, M.; Deng, Y.; Simons, V.; Tielens, E.; Kelly, J.; Horton, K.; Maji, S.; Sheldon, D.
10.1101/2022.10.28.513761 — ecology — Posted on 2022-10-31
92 Purkinje cardiomyocytes of the ventricular conduction system are highly diploid but not regenerative
Watanabe, H.; Tao, G.; Gan, P.; Westbury, B. C.; Cox, K. D.; Tjen, K.; Song, R.; Fishman, G. I.; Makita, T.; Sucov, H. M.
10.1101/2022.10.29.514354 — developmental biology — Posted on 2022-10-31
93 Different biological effects of exposure to far-UVC (222 nm) and near-UVC (254 nm) irradiation
Napoleao Tavares, R. S.; Adamoski, D.; Girasole, A.; Lima, E. N.; Justo-Junior, A. d. S.; Domingues, R. R.; Silveira, A. C. C.; Marques, R. E.; de Carvalho, M.; Ambrosio, A. L. B.; Paes Leme, A.; Dias, S. M. G.
10.1101/2022.10.28.514223 — cell biology — Posted on 2022-10-31
94 Single-cell transcriptomic atlas reveals increased regeneration in diseased human inner ears
Wang, T.; Ling, A. H.; Billings, S. E.; Hosseini, D. K.; Vaisbuch, Y.; Kim, G. S.; Atkinson, P. J.; Sayyid, Z. N.; Aaron, K. A.; Wagh, D.; Pham, N.; Scheibinger, M.; Ishiyama, A.; Santa Maria, P.; Blevins, N. H.; Jackler, R. K.; Heller, S.; Lopez, I. A.; Grillet, N.; Jan, T. A.; Cheng, A. G.
10.1101/2022.10.29.514378 — cell biology — Posted on 2022-10-31
97 Comprehensive investigation and regulatory function of lncRNAs engaged in western honey bee larval immune response to Ascosphaera apis invasion
yaping, Y.; xiaoxue, F.; qi, L.; jie, W.; zhang, w.; zongbing, C.; minghui, S.; xiaoyu, G.; peiyuan, Z.; dafu, C.; Guo, R.
10.1101/2022.10.28.514173 — pathology — Posted on 2022-10-31
98 PointVS: A Machine Learning Scoring Function that Identifies Important Binding Interactions
Scantlebury, J.; Vost, L.; Carbery, A.; Hadfield, T. E.; Turnbull, O. M.; Brown, N.; Chenthamarakshan, V.; Das, P.; Grosjean, H.; von Delft, F.; Deane, C. M.
10.1101/2022.10.28.511712 — bioinformatics — Posted on 2022-10-31
99 Probing lung function at high spatiotemporal resolution using a novel crystal ribcage
Banerji, R.; Grifno, G. N.; Shi, L.; Smolen, D.; LeBourdais, R.; Muhvich, J.; Eberman, C.; Hiller, B.; Lee, J.; Regan, K.; Zheng, S.; Zhang, S. S.; Pihl, R.; Traber, K.; Ligresti, G.; Mizgerd, J. P.; Suki, B.; Nia, H. T.
10.1101/2022.10.28.514251 — bioengineering — Posted on 2022-10-31
102 How do Vampires Suck Blood?
Gou, M.; Duan, X.; Li, J.; Wang, Y.; Li, Q.; Pang, Y.; Dong, Y.
10.1101/2022.10.31.514445 — biochemistry — Posted on 2022-10-31
105 SMDT1 variants impair EMRE-mediated mitochondrial calcium uptake in patients with muscle involvement
Bulthuis, E. P.; Adjobo-Hermans, M. J. W.; de Potter, B.; Hoogstraten, S.; Wezendonk, L. H. T.; Tutakhel, O. A. Z.; Wintjes, L. T.; van den Heuvel, L. P. W. J.; Willems, P. H. G. M.; Kamsteeg, E.-J.; Rubio Gozalbo, M. E.; Sallevelt, S. C. E. H.; Koudijs, S. M.; Nicolai, J.; de Bie, C. I.; Hoogendijk, J. E.; Koopman, W. J. H.; Rodenburg, R. J.
10.1101/2022.10.31.514480 — genetics — Posted on 2022-10-31
106 LSR Targets YAP to Modulate Intestinal Paneth Cell Differentiation
An, Y.; Wang, C.; Fan, B.; Li, Y.; Kong, F.; Zhou, C.; Cao, Z.; Liu, J.; Wang, M.; Sun, H.; Zhao, S.; Gong, Y.
10.1101/2022.10.30.514401 — cell biology — Posted on 2022-10-31
107 Lipid peroxidation increases membrane tension, Piezo1 gating and cation permeability to execute ferroptosis
Grinstein, S.; Hirata, Y.; Steinberg, B. E.; Volchuk, A.; matsuzawa, a.; Cai, R.; Freeman, S. A.
10.1101/2022.10.31.514557 — cell biology — Posted on 2022-10-31
108 Myoscaffolds demonstrate differential matrix components across muscular dystrophies
Long, A. M.; Kwon, J.; Reiser, N. L.; Vaught, L. A.; O'Brien, J. G.; Page, P. G. T.; Lee, G.; Hadhazy, M.; Reynolds, J. C.; Crosbie, R. H.; McNally, E. M.; Demonbreun, A. R.
10.1101/2022.10.31.514525 — molecular biology — Posted on 2022-10-31
109 First identification and investigation of piRNAs in the larval guts of Asian honey bee, Apis cerana
Long, Q.; Sun, M.; Fan, X.; Cai, Z.; Zhang, K.; Wang, S.; Zhang, J.; Gu, X.; Song, Y.; Chen, D.; Fu, Z.; Guo, R.; Niu, Q.
10.1101/2022.10.30.514393 — molecular biology — Posted on 2022-10-31
111 An Optimized Electrotransformation Protocol For Lactobacillus Jensenii.
Fristot, E.; Bessede, T.; Camacho Rufino, M.; Mayonove, P.; Chang, H.-J.; Zuniga, A.; Michon, A.-L.; Godreuil, S.; Bonnet, J.; Cambray, G.
10.1101/2022.10.31.514476 — microbiology — Posted on 2022-10-31
114 The molecular principles governing HCMV infection outcome
Schwartz, M.; Shnayder, M.; Nachshon, A.; Arazi, T.; Kitsberg, Y.; Levi Samia, R.; Lavi, M.; Kuint, R.; Tsabari, R.; Stern-Ginossar, N.
10.1101/2022.10.31.514490 — microbiology — Posted on 2022-10-31
115 Expression of terminal deoxynucleotidyl transferase (TdT) identifies lymphoid-primed progenitors in human bone marrow
Kim, Y.; Calderon, A. A.; Favaro, P.; Glass, D. R.; Tsai, A. G.; Borges, L.; Greenleaf, W. J.; Bendall, S. C.
10.1101/2022.10.30.514380 — immunology — Posted on 2022-10-31
116 The splicing switch of SLK controls tumor progression partially via different associations with occludin
Yang, Y.-Q.; Zhang, S.-R.; Hu, Y.; Li, J.; Guan, J.-W.; Zhang, W.-J.; Sun, Y.; Sun, J.; Yang, Y.; Wang, Z.; Wei, H.-H.
10.1101/2022.10.28.514146 — cancer biology — Posted on 2022-10-31
117 Structural basis for ion selectivity in potassium-selective channelrhodopsins
Tajima, S.; Kim, Y. S.; Fukuda, M.; Byrne, E. F. X.; Wang, P. Y.; Paggi, J. M.; Kishi, K. E.; Ramakrishnan, C.; Takaramoto, S.; Nagata, T.; Konno, M.; Sugiura, M.; Katayama, K.; Matsui, T. E.; Yamashita, K.; Ikeda, H.; Inoue, M.; Kandori, H.; Dror, R. O.; Inoue, K.; Deisseroth, K.; Kato, H. E.
10.1101/2022.10.30.514430 — biophysics — Posted on 2022-10-31
118 Toblerone: detecting exon deletion events in cancer using RNA-seq
Lonsdale, A.; Halman, A.; Brown, L.; Kosasih, H.; Ekert, P.; Oshlack, A.
10.1101/2022.10.27.514132 — bioinformatics — Posted on 2022-10-31
119 Transformer-based deep learning integrates multi-omic data with cancer pathways
Cai, Z.; Poulos, R. C.; Aref, A.; Robinson, P. J.; Reddel, R. R.; Zhong, Q.
10.1101/2022.10.27.514141 — bioinformatics — Posted on 2022-10-31
121 Simultaneous global labeling (SiGL) of 5-methylcytosine and 5-hydroxymethylcytosine by DNA alkylation with a synthetic cofactor and engineered methyltransferase
Avraham, S.; schuetz, L.; Kaever, L.; Dankers, A.; Margalit, S.; Michaeli, Y.; Zirkin, S.; Torchinsky, D.; Gilat, N.; Bahr, O.; Nifker, G.; Koren-Michowitz, M.; Weinhold, E.; Ebenstein, Y.
10.1101/2022.10.31.513813 — genetics — Posted on 2022-10-31
122 Regulatory effects of miRNA-19a on MAD2 expression and tumorigenesis in gastric cancer.
Bargiela Iparraguirre, J.; Melones Herrero, J.; Pajuelo Lozano, N.; Perez Martinez, M. d. M.; Cales Bourdet, M. d. C.; Perona Abellon, R.; Gomez Quiroga, A.; Sanchez-Perez, I.
10.1101/2022.10.31.514416 — molecular biology — Posted on 2022-10-31
123 Epigenetically silencing gluconeogenic enzyme PCK1 by EZH2 promotes renal tubulointerstitial fibrosis
Wu, M.; Chen, D.; Wang, Y.; Lin, P.; Yang, F.; Lin, J.; Tan, B.; Sheng, G.; Yang, X.; Huang, D.; Ye, C.
10.1101/2022.10.31.514497 — molecular biology — Posted on 2022-10-31
124 Genomic Sequencing from Sputum for Tuberculosis Disease Diagnosis, Lineage Determination and Drug Susceptibility Prediction
Nilgiriwala, K.; Rabodoarivelo, M.-S.; Hall, M. B.; Patel, G.; Mandal, A.; Mishra, S.; Andrianomanana, F. R.; Dingle, K.; Rodger, G.; George, S.; Crook, D. W.; Hoosdally, S.; Mistry, N.; Rakotosamimanana, N.; Iqbal, Z.; Grandjean Lapierre, S.; Walker, T. M.
10.1101/2022.10.31.514503 — microbiology — Posted on 2022-10-31
127 Platelets favor the outgrowth of established metastases
Garcia-Leon, M. J.; Lefebvre, O.; Follain, G.; Mouriaux, C.; Busnelli, I.; Larnicol, A.; Colin, F.; Mittelheisser, V.; Peralta, M.; Bourdon, C.; Samaniego, R.; Mangin, P. H.; GOETZ, J. G.
10.1101/2022.10.28.514195 — cancer biology — Posted on 2022-10-31
128 Development of a yeast whole-cell biocatalyst for MHET conversion into terephthalic acid and ethylene glycol
Loll-Krippleber, R.; Sajtovich, V.; Ferguson, M.; Ho, B.; Payliss, B.; Bellissimo, J.; Peters, S.; Wyatt, H. D. M.; Brown, G. W.
10.1101/2022.10.30.514423 — synthetic biology — Posted on 2022-10-31
129 Natural heteroclitic-like peptides are generated by SARS-CoV-2 mutations
Tiezzi, C.; Vecchi, A.; Rossi, M.; Cavazzini, D.; Bolchi, A.; Laccabue, D.; Sacchelli, L.; Brillo, F.; Meschi, T.; Ticinesi, A.; Nouvenne, A.; Donofrio, G.; Zanelli, P.; Benecchi, M.; Giuliodori, S.; Fisicaro, P.; Montali, I.; Urbani, S.; Pedrazzi, G.; Missale, G.; Telenti, A.; Corti, D.; Ottonello, S.; Ferrari, C.; Boni, C.
10.1101/2022.10.28.513849 — immunology — Posted on 2022-10-31
130 RAPTOR: A Five-Safes approach to a secure, cloud native and serverless genomics data repository
Shih, C. C.; Chen, J.; Lee, A. S.; Bertin, N.; Hebrard, M.; Khor, C. C.; Li, Z.; Tan, J. H. J.; Meah, W. Y.; Peh, S. Q.; Mok, S. Q.; Sim, K. S.; Liu, J.; Wang, L.; Wong, E.; Li, J.; Tin, A.; Cheng, C.-Y.; Heng, C.-K.; Yuan, J.-M.; Koh, W.-P.; Saw, S. M.; Friedlander, Y.; Sim, X.; Chai, J. F.; Chong, Y. S.; Davila, S.; Goh, L. L.; Lee, E. S.; Wong, T. Y.; Karnani, N.; Leong, K. P.; Yeo, K. K.; Chambers, J. C.; Lim, S. C.; Goh, R. S. M.; Tan, P.; Dorajoo, R.
10.1101/2022.10.27.514127 — genomics — Posted on 2022-10-31
131 Genotypic sex shapes maternal care in the African Pygmy mouse, Mus minutoides
Heitzmann, L. D.; Challe, M.; Perez, J.; Castell, L.; Galibert, E.; Martin, A.; Valjent, E.; Veyrunes, F.
10.1101/2022.04.05.487174 — evolutionary biology — Posted on 2022-10-31
132 The Vogt-Bailey index: a local gradient analysis
Farrugia, C.; Galdi, P.; Arenzana Irazu, I.; Scerri, K.; Bajada, C. J.
10.1101/2022.10.14.511925 — neuroscience — Posted on 2022-10-31
133 The plastidial protein MRC promotes starch granule initiation in wheat leaves but delays B-type granule initiation in the endosperm
Chen, J.; Chen, Y.; Watson-Lazowski, A.; Hawkins, E.; Barclay, J. E.; Fahy, B.; Denley-Bowers, R.; Corbin, K.; Warren, F. J.; Blennow, A.; Uauy, C.; Seung, D.
10.1101/2022.10.07.511297 — plant biology — Posted on 2022-10-31
134 Ubiquitination steers SRF3 plasma membrane nano-organization to specify signaling outputs
Platre, M. P.; Gleason, M. F.; Brent, L.; Cao, M.; Zhang, L.; Satbhai, S. B.; Neveu, J.; Vert, G.; Busch, W.
10.1101/2022.10.28.514292 — plant biology — Posted on 2022-10-31
139 Spinal premotor interneurons controlling antagonistic muscles are spatially intermingled
Ronzano, R.; Skarlatou, S.; Barriga, B. K.; Bannatyne, B. A.; Bhumbra, G. S.; Foster, J. D.; Moore, J.; Lancelin, C.; Pocratsky, A.; Ozyurt, M. G.; Smith, C. C.; Todd, A. J.; Maxwell, D. J.; Murray, A. J.; Pfaff, S. L.; Brownstone, R. M.; Zampieri, N.; Beato, M.
10.1101/2021.02.10.430608 — neuroscience — Posted on 2022-10-31
141 An energy-saving glasshouse film reduces seasonal, and cultivar dependent Capsicum yield due to light limited photosynthesis
Chavan, S. G.; He, X.; Maier, C.; ALAGOZ, Y.; Anwar, S.; Chen, Z.; Ghannoum, O.; Cazzonelli, C. I.; Tissue, D. T.
10.1101/2022.10.29.513818 — plant biology — Posted on 2022-10-31
148 The neuropeptidergic connectome of C. elegans
Sanchez, L. R.; Watteyne, J.; Sun, H.; Fernandez, R.; Taylor, S.; Weinreb, A.; Hammarlund, M.; Miller, D.; Hobert, O.; Beets, I.; Vertes, P.; Schafer, W.
10.1101/2022.10.30.514396 — neuroscience — Posted on 2022-10-31
150 Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution
Cao, Y.; Jian, F.; Wang, J.; Yu, Y.; Song, W.; Yisimayi, A.; Wang, J.; An, R.; Chen, X.; Zhang, N.; Wang, Y.; Wang, P.; Zhao, L.; Sun, H.; Yu, L.; Yang, S.; Niu, X.; Xiao, T.; Gu, Q.; Shao, F.; Hao, X.; Xu, Y.; Jin, R.; Shen, Z.; Wang, Y.; Xie, X. S.
10.1101/2022.09.15.507787 — immunology — Posted on 2022-10-30
153 An In Vivo Analysis of the Functional Motifs of DEAD-box RNA Helicase Me31B in Drosophila Fertility and Germline Development
Kara, E.; McCambridge, A. H.; Proffer, M.; Dilts, C.; Pumnea, B.; Eshak, J.; Smith, K. A.; Fielder, I.; Doyle, D. A.; Ortega, B. M.; Mukatash, Y.; Malik, N.; Mohammed, A. R.; Govani, D.; Niepielko, M. G.; Gao, M.
10.1101/2022.10.04.510704 — developmental biology — Posted on 2022-10-30
154 Optimised DNA isolation from marine sponges for natural sampler DNA (nsDNA) metabarcoding
Harper, L. R.; Neave, E. F.; Sellers, G. S.; Cunnington, A. V.; Arias, M. B.; Craggs, J.; MacDonald, B.; Riesgo, A.; Mariani, S.
10.1101/2022.07.11.499619 — molecular biology — Posted on 2022-10-30
156 A non-human primate model with Alzheimer's disease-like pathology induced by hippocampal overexpression of human tau
Jiang, Z.; Wang, J.; Luo, B.; Bai, F.; Qin, Y.; Wei, H.; Zhang, S.; Wei, J.; Ding, G.; Ma, L.; He, S.; Chen, R.; Wang, L.; Xu, H.; Wang, X.; Chen, G.; Lei, W.
10.1101/2022.10.26.513832 — neuroscience — Posted on 2022-10-30
157 The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies
Yu, D. S.; Outram, M. A.; Smith, A.; McCombe, C. L.; Khambalkar, P. B.; Rima, S. A.; Sun, X.; Ma, L.; Ericsson, D. J.; Jones, D. A.; Williams, S. J.
10.1101/2021.12.14.472499 — plant biology — Posted on 2022-10-30
160 MR-DoC2: bidirectional causal modeling with instrumental variables and data from relatives
Araujo, L. F.; Singh, M.; Zhou, Y. D.; Vinh, P.; Verhulst, B.; Dolan, C. V.; Neale, M. C.
10.1101/2022.03.14.484271 — genetics — Posted on 2022-10-30
165 Obox4 secures zygotic genome activation upon loss of Dux
Guo, Y.; Kitano, T.; Inoue, K.; Murano, K.; Hirose, M.; Li, T. D.; Sakashita, A.; Ishizu, H.; Ogonuki, N.; Matoba, S.; Sato, M.; Ogura, A.; Siomi, H.
10.1101/2022.07.04.498763 — molecular biology — Posted on 2022-10-30
166 Glycoengineered keratinocyte library reveals essential functions of specific glycans for all stages of HSV-1 life cycle
Bagdonaite, I.; Marinova, I. N.; Rudjord-Levann, A. M.; Pallesen, E. M.; King-Smith, S.; Roemer, T. B.; Chen, Y.-H.; Dabelsteen, S.; Wandall, H. H.
10.1101/2022.10.23.513399 — microbiology — Posted on 2022-10-30
167 Panoramic visual statistics shape retina-wide organization of receptive fields
Gupta, D.; Mlynarski, W.; Sumser, A.; Symonova, O.; Svaton, J.; Joesch, M.
10.1101/2022.01.11.475815 — neuroscience — Posted on 2022-10-30
171 Rho activation drives luminal collapse and eversion in epithelial acini
Narayanan, V.; Purkayastha, P.; Yu, B.; Pendyala, K.; Chukkapalli, S.; Cabe, J. I.; Dickinson, R. B.; Conway, D. E.; Lele, T. P.
10.1101/2022.07.06.499064 — biophysics — Posted on 2022-10-30
172 Extending the Boundaries of Cancer Therapeutic Complexity with Literature Data Mining
Niezni, D.; Taub-Tabib, H.; Harris, Y.; Sason-Bauer, H.; Amrusi, Y.; Azagury, D.; Avrashami, M.; Launer-Wachs, S.; Borchard, J.; Kusold, M.; Tiktinsky, A.; Hope, T.; Goldberg, Y.; Shamay, Y.
10.1101/2022.05.03.490286 — bioinformatics — Posted on 2022-10-30
182 Dissociation of reliability, predictability, and heritability in fine- and coarse-scale functional connectomes during development
Busch, E. L.; Rapuano, K. M.; Anderson, K. M.; Rosenberg, M. D.; Watts, R.; Casey, B.; Haxby, J. V.; Feilong, M.
10.1101/2022.05.24.493295 — neuroscience — Posted on 2022-10-30
184 Spatiotemporal coordination of stem cell behavior following alveolar injury
Chioccioli, M.; Magruder, S.; McDonough, J. E.; Nouws, J.; Gonzalez, D.; Borriello, L.; Traub, B.; Ye, X.; Hendry, C. E.; Entenberg, D.; Kaminski, N.; Krishnaswamy, S.; Sauler, M.
10.1101/2022.10.28.514255 — cell biology — Posted on 2022-10-30
185 Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids
Nguyen Ngoc, K. V.; Sai, S.; Jun, Y.; Bender, R. H. F.; Kravets, V.; Zhu, H.; Hatch, C. J.; Schlichting, M.; Gaetani, R.; Mallick, M.; Hachey, S. J.; Christman, K.; George, S. C.; Hughes, C. C.; Sander, M.
10.1101/2022.10.28.513298 — cell biology — Posted on 2022-10-30
187 Linking Choroid Plexus Enlargement with Plasma Analyte and Structural Phenotypes in Clinical High Risk for Psychosis: A Multisite Neuroimaging Study
Bannai, D.; Reuter, M.; Hegde, R.; Hoang, D.; Adhan, I.; Gandu, S.; Pong, S.; Zeng, A.; Raymond, N.; Zeng, V.; Chung, Y.; He, G.; Sun, D.; van Erp, T. G. M.; Addington, J.; Bearden, C. E.; Cadenhead, K.; Cornblatt, B.; Mathalon, D. H.; McGlashan, T.; Jeffries, C.; Stone, W.; Tsuang, M.; Walker, E.; Woods, S. W.; Cannon, T. D.; Perkins, D.; Keshavan, M.; Lizano, P.
10.1101/2022.10.28.514160 — neuroscience — Posted on 2022-10-30
189 Primary motor cortex drives expressive facial movements related to reward processing in mice
Li, W.; Nakano, T.; Mizutani, K.; Kawatani, M.; Matsubara, T.; Danjo, T.; Mukai, Y.; Yamanaka, A.; Ito, H.; Aizawa, H.; Petersen, C. C.; Yoshimoto, J.; Yamashita, T.
10.1101/2022.10.28.514159 — neuroscience — Posted on 2022-10-30
192 Functional Integration of 3D-Printed Cerebral Cortical Tissue into a Brain Lesion
Jin, Y.; Mikhailova, E.; Lei, M.; Cowley, S. A.; Sun, T.; Yang, X.; Zhang, Y.; Liu, K.; Catarino, D.; Soares, L. C.; Bandiera, S.; Szele, F. G.; Molnar, Z.; Zhou, L.; Bayley, H.
10.1101/2022.10.28.513987 — bioengineering — Posted on 2022-10-30
193 Distinct Wolbachia localization patterns in oocytes of diverse host species reveal multiple strategies of maternal transmission
Radousky, Y. A.; Hague, M. T. J.; Fowler, S.; Paneru, E.; Codina, A.; Rugamas, C.; Hartzog, G.; Cooper, B. S.; Sullivan, W.
10.1101/2022.10.28.514302 — cell biology — Posted on 2022-10-30
197 Whole Human-Brain Mapping of Single Cortical Neurons for Profiling Morphological Diversity and Stereotypy
Han, X.; Guo, S.; Ji, N.; Li, T.; Liu, J.; Ye, X.; Wang, Y.; Yun, Z.; Xiong, F.; Rong, J.; Liu, D.; Ma, H.; Wang, Y.; Huang, Y.; Zhang, P.; Wu, W.; Ding, L.; Hawrylycz, M.; Lein, E.; Ascoli, G. A.; Xie, W.; Liu, L.; Zhang, L.; Peng, H.
10.1101/2022.10.29.514375 — neuroscience — Posted on 2022-10-30
199 Poorer Sleep Health is Associated with Altered Cognitive Control Processing in Healthy Adults
Smevik, H.; Habli, S.; Saksvik, S. B.; Kliem, E.; Evensmoen, H. R.; Conde, V.; Petroni, A.; Asarnow, R. F.; Dennis, E. L.; Eikenes, L.; Kallestad, H.; Sand, T.; Thompson, P. M.; Saksvik-Lehouillier, I.; Haberg, A. K.; Olsen, A.
10.1101/2022.10.28.512671 — neuroscience — Posted on 2022-10-30
200 Role of mesolimbic endocannabinoid signaling in stress-driven cocaine use in rats
McReynolds, J. R.; Wolf, C. P.; Starck, D. M.; Schaps, R.; Krause, L. A.; Hillard, C. J.; Mantsch, J. R.
10.1101/2022.10.28.514315 — neuroscience — Posted on 2022-10-30
201 Disentangling the role of NAc D1 and D2 cells in hedonic eating
Guillaumin, M. C. C.; Viskaitis, P.; Bracey, E.; Burdakov, D.; Peleg-Raibstein, D.
10.1101/2022.10.29.514339 — neuroscience — Posted on 2022-10-30
204 Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial tauopathy
Sirkis, D. W.; Warly Solsberg, C.; Johnson, T. P.; Bonham, L. W.; Sturm, V. E.; Lee, S. E.; Rankin, K. P.; Rosen, H. J.; Boxer, A. L.; Seeley, W. W.; Miller, B. L.; Geier, E. G.; Yokoyama, J. S.
10.1101/2022.10.28.514304 — neuroscience — Posted on 2022-10-30
206 PNPO-PLP Axis Senses Prolonged Hypoxia by Regulating Lysosomal Activity
Sekine, H.; Takeda, H.; Kishino, A.; Anzawa, H.; Isagawa, T.; Ota, N.; Kato, N.; Kimura, S.; Liu, Z.; Kato, K.; Katsuoka, F.; Yamamoto, M.; Miura, F.; Ito, T.; Takahashi, M.; Izumi, Y.; Fujita, H.; Yamagata, H.; Takeda, N.; Bamba, T.; Suzuki, N.; Kinoshita, K.; Motohashi, H.
10.1101/2022.10.28.514185 — biochemistry — Posted on 2022-10-30
209 Distribution and survival strategies of diazotrophs in the Arctic Ocean revealed by global-scale metagenomic analysis
Shiozaki, T.; Nishimura, Y.; Yoshizawa, S.; Takami, H.; Hamasaki, K.; Fujiwara, A.; Nishino, S.; Harada, N.
10.1101/2022.10.28.514325 — ecology — Posted on 2022-10-30
210 Hormone-induced enhancer assembly requires an optimal level of hormone receptor multivalent interactions
Chen, L.; Zhang, Z.; Han, Q.; Rodrigues, L.; Zboril, E.; Adhikari, R.; Li, X.; Ko, S.-H.; Xue, P.; Smith, E.; Xu, K.; Wang, Q.; Huang, T. H.-M.; Chong, S.; Liu, Z.
10.1101/2022.10.28.514297 — molecular biology — Posted on 2022-10-30
212 Versatile methanotrophs form an active methane biofilter in the oxycline of a seasonally stratified coastal basin
Venetz, J.; Zygadłowska, O. M.; Lenstra, W. K.; Van Helmond, N. A. G. M.; Dalcin Martins, P.; Wallenius, A. J.; Nuijten, G. G. H. L.; Slomp, C. P.; Jetten, M. S. M.; Veraart, A. J.
10.1101/2022.10.28.513710 — microbiology — Posted on 2022-10-30
216 Vascular endothelial growth factor A contributes to the increasing of mammalian respiratory epithelial permeability induced by Pasteurella multocida infection
Lin, L.; Yang, J.; Zhang, D.; Lv, Q.; Wang, F.; Liu, P.; Wang, M.; Shi, C.; Huang, X.; Liang, W.; Tan, C.; Wang, X.; Chen, H.; Wilson, B. A.; Wu, B.; Peng, Z.
10.1101/2022.10.28.514333 — microbiology — Posted on 2022-10-30
220 G-PROTEIN COUPLED RECEPTOR 19 (GPR19) KNOCKOUT MICE DISPLAY SEX-DEPENDENT METABOLIC DYSFUNCTION
Mushala, B. A. S.; Xie, B.; Sipula, I.; Stoner, M. W.; Thapa, D.; Manning, J. R.; Bugga, P.; Vandevender, A. M.; Jurczak, M. J.; Scott, I.
10.1101/2022.10.29.514377 — physiology — Posted on 2022-10-30
221 Improving the sensitivity of in vivo CRISPR off-target detection with DISCOVER-Seq+
Zou, R. S.; Liu, Y.; Reyes Gaido, O. E.; Konig, M. F.; Mog, B. J.; Shen, L. L.; Aviles-Vazquez, F.; Marin-Gonzalez, A.; Ha, T.
10.1101/2022.10.29.514376 — bioengineering — Posted on 2022-10-30
227 Single-domain antibody delivery using an mRNA platform protects against lethal doses of botulinum neurotoxin A
Panova, E. A.; Kleymenov, D. A.; Shcheblyakov, D. V.; Bykonia, E. N.; Mazunina, E. P.; Dzharullaeva, A. S.; Zolotar, A. N.; Derkaev, A. A.; Esmagambetov, I. B.; Sorokin, I. I.; Usachev, E. V.; Ivanov, I. A.; Zatsepin, T. S.; Dmitriev, S. E.; Gushchin, V. A.; Logunov, D. Y.; Gintsburg, A. L.
10.1101/2022.10.29.514343 — molecular biology — Posted on 2022-10-30
228 GNL3 regulates replication origin firing and protects stalled replication forks
Lebdy, R.; Canut, M.; Patouillard, J.; Cadoret, J.-C.; Letessier, A.; Ammar, J.; Basbous, J.; Urbach, S.; Miotto, B.; Constantinou, A.; Abou Merhi, R.; Ribeyre, C.
10.1101/2022.10.27.514025 — molecular biology — Posted on 2022-10-30
229 Prophage taming by the adherent-invasive Escherichia coli LF82 upon macrophage infection
Misson, P.; Bruder, E.; Cornuault, J. K.; De Paepe, M.; Demarre, G.; Petit, M.-A.; Espeli, O.; Lecointe, F.
10.1101/2022.10.28.514194 — microbiology — Posted on 2022-10-30
231 Quorum sensing peptidic inhibitor rescue host immune system eradication: a novel QS infectivity mechanism
Yehuda, A.; Malach, E.; Slamti, L.; Shuan Kuo, S.; Z. Lau, J.; Whan Oh, M.; Adeoye, J.; Shlezinger, N.; Lau, G.; Lereclus, D.; Hayouka, Z.
10.1101/2022.10.28.514287 — microbiology — Posted on 2022-10-30
232 An alternative malonyl-CoA producing pathway in nature
Liu, B.; Zhang, Y.; Cui, Q.; Wu, S.; Tang, S.; Chen, Y.; Ma, Y.; Liu, W.; Tao, Y.
10.1101/2022.10.28.514148 — microbiology — Posted on 2022-10-30
233 Formation and three-dimensional architecture of Leishmania adhesion in the sand fly vector
Yanase, R.; Moreira-Leite, F.; Rea, E.; Wilburn, L.; Sadlova, J.; Vojtkova, B.; Pruzinova, K.; Taniguchi, A.; Nonaka, S.; Volf, P.; Sunter, J. D.
10.1101/2022.10.28.514187 — microbiology — Posted on 2022-10-30
234 Biogeographic Distribution of Five Antarctic Cyanobacteria Using Large-Scale k-mer Searching with sourmash branchwater
Lumian, J.; Sumner, D.; Grettenberger, C.; Jungblut, A. D.; Irber, L.; Pierce-Ward, N. T.; Brown, C. T.
10.1101/2022.10.27.514113 — microbiology — Posted on 2022-10-30
235 The E2F4/p130 repressor complex cooperates with oncogenic ΔNp73α to promote cell survival in human papillomavirus 38 E6/E7-transformed keratinocytes and in cancer cells
Taverniti, V.; Krynska, H.; Venuti, A.; Straub, M.-L.; Sirand, C.; Lohmann, E.; Romero-Medina, M. C.; Moro, S.; Robitaille, A.; Negroni, L.; Martinez-Zapien, D.; Masson, M.; Tommasino, M.; Zanier, K.
10.1101/2022.10.27.514150 — cancer biology — Posted on 2022-10-30
236 The BRAIN Initiative Cell Census Data Ecosystem: A User's Guide
BICCN Data Ecosytem Collaboration, ; Hawrylycz, M. J.; Martone, M. E.; Hof, P. R.; Lein, E. S.; Regev, A.; Ascoli, G. A. A.; Bjaalie, J. G.; Dong, H.-W.; Ghosh, S. S.; Gillis, J.; Hertzano, R.; Haynor, D. R.; Kim, Y.; Liu, Y.; Miller, J. A.; Mitra, P. P.; Mukamel, E.; Osumi-Sutherland, D.; Peng, H.; Ray, P. L.; Sanchez, R.; Ropelewski, A.; Scheuermann, R. H.; Tan, S. Z. K.; Tickle, T.; Tilgner, H.; Varghese, M.; Wester, B.; White, O.; Aevermann, B.; Allemang, D.; Ament, S.; Athey, T. L.; Baker, P. M.; Baker, C.; Baker, K. S.; Bandrowski, A.; Bishwakarma, P.; Carr, A.; Chen, M.; Choudhury, R.;
10.1101/2022.10.26.513573 — bioinformatics — Posted on 2022-10-30
238 A cold-blooded vertebrate shows integration of antimicrobial defenses and tissue repair through fever
Haddad, F.; Soliman, A. M.; Wong, M. E.; Albers, E. H.; Semple, S. L.; Torrealba, D.; Heimroth, R. D.; Nashiry, A.; Tierney, K. B.; Barreda, D. R.
10.1101/2022.10.27.513985 — immunology — Posted on 2022-10-30
239 Intratumoral heterogeneity and clonal evolution induced by HPV integration
Akagi, K.; Symer, D. E.; Mahmoud, M.; Jiang, B.; Goodwin, S.; Wangsa, D.; Li, Z.; Xiao, W.; Dunn, J. D.; Ried, T.; Coombes, K. R.; Sedlazeck, F. J.; Gillison, M. L.
10.1101/2022.08.11.503647 — cancer biology — Posted on 2022-10-30
240 Large effect loci have a prominent role in Darwin's finch evolution
Enbody, E. D.; Sendell-Price, A. T.; Sprehn, C. G.; Rubin, C.-J.; Visscher, P. M.; Grant, B. R.; Andersson, L.
10.1101/2022.10.29.514326 — evolutionary biology — Posted on 2022-10-30
242 Oligodendrocyte precursor cells stop sensory axons regenerating into the spinal cord
Kim, H.; Skuba, A.; Xia, J.; Han, S. B.; Zhai, J.; Hu, H.; Kang, S. H.; Son, Y.-J.
10.1101/2022.09.28.509944 — neuroscience — Posted on 2022-10-30
243 A spatiotemporal map of the aging mouse brain reveals white matter tracts as vulnerable foci
Hahn, O.; Foltz, A. G.; Atkins, M.; Kedir, B.; Moran-Losada, P.; Guldner, I. H.; Munson, C.; Kern, F.; Palovics, R.; Lu, N.; Kaur, A.; Hull, J.; Huguenard, J.; Keller, A.; Lehallier, B.; Wyss-Coray, T.
10.1101/2022.09.18.508419 — neuroscience — Posted on 2022-10-30
245 Aligning Distant Sequences to Graphs using Long Seed Sketches
Joudaki, A.; Meterez, A.; Mustafa, H.; Koerkamp, R. G.; Kahles, A.; Raetsch, G.
10.1101/2022.10.26.513890 — bioinformatics — Posted on 2022-10-30
246 High-resolution promoter interaction analysis in Type 3 Innate Lymphoid Cells implicates Batten Disease gene CLN3 in Crohn's Disease aetiology
Malysheva, V.; Ray-Jones, H.; Cazares, T. A.; Clay, O.; Ohayon, D.; Artemov, P.; Wayman, J. A.; Della Rosa, M.; Petitjean, C.; Booth, C.; Ellaway, J. I. J.; Orchard, W.; Chen, X.; Parameswaran, S.; Nagano, T.; Fraser, P.; Schoenfelder, S.; Weirauch, M.; Kottyan, L. C.; Smith, D. F.; Powell, N.; Weimer, J.; Wallace, C.; Miraldi, E. R.; Waggoner, S.; Spivakov, M.
10.1101/2022.10.19.512842 — genetics — Posted on 2022-10-29
249 Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
Berquez, M.; Chen, Z.; Festa, B. P.; Krohn, P.; Keller, S. A.; Parolo, S.; Laczko, E.; Domenici, E.; Devuyst, O.; Luciani, A.
10.1101/2022.08.28.505580 — cell biology — Posted on 2022-10-29
251 Three-dimensional imaging and single-cell transcriptomics of the human kidney implicate perturbation of lymphatics in alloimmunity
Jafree, D. J.; Stewart, B.; Kolatsi-Joannou, M.; Davis, B.; Mitchell, H.; Russell, L. G.; Marinas del Rey, L.; Mason, W. J.; Lee, B. I.; Heptinstall, L.; Pomeranz, G.; Moulding, D.; Wilson, L.; Wickenden, T.; Malik, S.; Holroyd, N.; Walsh, C.; Chandler, J. C.; Cao, K. X.; Winyard, P. J.; Price, K. L.; Woolf, A. S.; Busche, M. A.; Walker-Samuel, S.; Scambler, P. J.; Motallebzadeh, R.; Clatworthy, M. R.; Long, D. A.
10.1101/2022.10.28.514222 — immunology — Posted on 2022-10-29
254 Central Nervous System axonal regeneration by spatially targeted drug combinations
Siddiq, M. M.; Johnson, N. P.; Zorina, Y.; Yadaw, A.; Hansen, J.; Rabinovich, V.; Gregorich, S. M.; Xiong, Y.; Tolentino, R. E.; Hannila, S. S.; Kaplan, E.; Blitzer, R. D.; Filbin, M. T.; Passaglia, C. L.; Toro, C. A.; Cardozo, C. P.; Iyengar, R.
10.1101/157099 — neuroscience — Posted on 2022-10-29
260 Peptides Mimicking RS Repeats Modulate Phase Separation of SRSF1, Revealing a Reliance on Combined Stacking and Electrostatic Interactions
Fargason, T. E.; De Silva, N. I. U.; King, E. M.; Zhang, Z.; Paul, T. M.; Shariq, J. A.; Zaharias, S. M.; Zhang, J.
10.1101/2022.10.24.511151 — biochemistry — Posted on 2022-10-29
265 Potentiation of Adipogenesis by Reactive Oxygen Species is a Unifying Mechanism in the Pro-adipogenic Properties of Bisphenol A and its New Structural Analogues.
Singh, R. D.; Wager, J. L.; Scheidl, T. B.; Connors, L. T.; Easson, S.; Callaghan, M. A.; Alatorre-hinojosa, S.; Swift, L. H.; Colarusso, P.; Jadli, A.; SHUTT, T.; Patel, V.; Thompson, J.
10.1101/2022.09.08.507176 — molecular biology — Posted on 2022-10-29
266 Tryptophol acetate and tyrosol acetate, small molecule metabolites identified in a probiotic mixture, inhibit hyperinflammation
malka, o.; malishev, r.; bersudsky, m.; rajendran, m.; krishnamohan, m.; shaik, j.; chamovitz, d.; tikhonov, e.; sultan, e.; koren, o.; apte, r.; rosental, b.; voronov, e.; jelinek, r.
10.1101/2021.12.16.472991 — immunology — Posted on 2022-10-29
271 Early Path Dominance as a Principle for Neurodevelopment
Razban, R. M.; Pachter, J. A.; Dill, K. A.; Mujica-Parodi, L. R.
10.1101/2022.07.14.500044 — neuroscience — Posted on 2022-10-29
273 Cross Atlas Remapping via Optimal Transport (CAROT): Creating connectomes for any atlas when raw data is not available
Dadashkarimi, J.; Karbasi, A.; Liang, Q.; Rosenblatt, M.; Noble, S.; Foster, M.; Rodriguez, R.; Adkinson, B.; Ye, J.; Sun, H.; Camp, C.; Farruggia, M.; Tejavibulya, L.; Dai, W.; Jiang, R.; Pollatou, A.; Scheinost, D.
10.1101/2022.07.19.500642 — neuroscience — Posted on 2022-10-29
275 SMbiot: A Shared Latent Model for Microbiomes and their Hosts
Krishnamurthy, M.; Herron, L.; Susanti, D.; Volland-Munson, A.; Plata, G.; Dixit, P. D.
10.1101/2022.10.28.514090 — systems biology — Posted on 2022-10-29
277 Chronic Jetlag Accelerates Pancreatic Neoplasia in Conditional Kras-Mutant Mice
Schwartz, P. B.; Walcheck, M. T.; Nukaya, M.; Pavelec, D. M.; Matkowskyj, K. A.; Ronnekleiv-Kelly, S. M.
10.1101/2022.07.18.500370 — cancer biology — Posted on 2022-10-29
278 Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis
Luo, Z.; Xia, M.; Shi, W.; Zhao, C.; Wang, J.; Xin, D.; Dong, X.; Xiong, Y.; Zhang, F.; Berry, K.; Ogurek, S.; Liu, X.; Rao, R.; Xing, R.; Wu, L. M. N.; Cui, S.; Xu, L.; Lin, Y.; Ma, W.; Tian, S.; Xie, Q.; Zhang, L.; Xin, M.; Wang, X.; Yue, F.; Zheng, H.; Liu, Y.; Stevenson, C. B.; Blank, P. d.; Perentesis, J. P.; Gilbertson, R.; Ma, J.; Li, H.; Zhou, W.; Tayler, M. D.; Lu, R.
10.1101/2022.08.17.504304 — cancer biology — Posted on 2022-10-29
282 SalienceNet: an unsupervised Image-to-Image translation method for nuclei saliency enhancement in microscopy images
Bouilhol, E.; Lefevre, E.; Barry, T.; Levet, F.; Beghin, A.; Viasnoff, V.; Galindo, X.; Galland, R.; Sibarita, J.-B.; Nikolski, M.
10.1101/2022.10.27.514030 — bioinformatics — Posted on 2022-10-29
285 In Silico Analysis of Novel VHL Germline Mutations in Iranian RCH Patients
Naseripour, M.; Bagherzade, K.; Khakpoor, G.; Sedaghat, A.; Mirshahi, R.; Kasraee, H.; Kiaee, R. A.; Azimi, F.
10.1101/2022.10.26.513811 — genetics — Posted on 2022-10-29
286 Searching across-cohort relatives via encrypted genotype regression
Zhang, Q.-X.; Liu, T.; Guo, X.; Zhen, J.; Bao, K.; Yang, M.-y.; Khederzadeh, S.; Zhou, F.; Han, X.; Zheng, Q.; Jia, P.; Ding, X.; He, M.; Zou, X.; Zhang, H.; He, J.; Zhu, X.; Zou, Y.; Lu, S.; Lu, D.; Chen, H.; Zeng, C.; Liu, F.; Zheng, H.-F.; Liu, S.; Xu, H.; Chen, G.-B.
10.1101/2022.10.18.512407 — genetics — Posted on 2022-10-29
290 Plankton-infecting relatives of herpesviruses clarify the evolutionary trajectory of giant viruses
Gaia, M.; Meng, L.; Pelletier, E.; Forterre, P.; Vanni, C.; Fernendez-Guerra, A.; Jaillon, O.; Wincker, P.; Ogata, H.; Krupovic, M.; Delmont, T. O.
10.1101/2021.12.27.474232 — evolutionary biology — Posted on 2022-10-29
291 Mood variability during adolescent development and its relation to sleep and brain development
Toenders, Y. J.; van der Cruijsen, R.; Runze, J.; van de Groep, S.; Wierenga, L.; Crone, E. A.
10.1101/2022.08.23.505008 — developmental biology — Posted on 2022-10-29
293 ASO targeting temperature-controlled RBM3 poison exon splicing prevents neurodegeneration in vivo
Preussner, M.; Smith, H. L.; Zhang, M.; Hughes, D.; Emmerichs, A.-K.; Scalzitti, S.; Peretti, D.; Swinden, D.; Neumann, A.; Haltenhof, T.; Mallucci, G. R.; Heyd, F.
10.1101/2022.10.26.513170 — molecular biology — Posted on 2022-10-29
294 Large-scale phylogenomics of aquatic bacteria reveal molecular mechanisms for adaptation to salinity
Jurdzinski, K. T.; Mehrshad, M.; Delgado, L. F.; Deng, Z.; Bertilsson, S.; Andersson, A. F.
10.1101/2022.10.03.510577 — microbiology — Posted on 2022-10-29
296 Spinal premotor interneurons controlling antagonistic muscles are spatially intermingled
Ronzano, R.; Skarlatou, S.; Barriga, B. K.; Bannatyne, B. A.; Bhumbra, G. S.; Foster, J. D.; Moore, J.; Lancelin, C.; Pocratsky, A.; Ozyurt, M. G.; Smith, C. C.; Todd, A. J.; Maxwell, D. J.; Murray, A. J.; Pfaff, S. L.; Brownstone, R. M.; Zampieri, N.; Beato, M.
10.1101/2021.02.10.430608 — neuroscience — Posted on 2022-10-29
299 Within-animal comparison of microdialysis and fiber photometry in amphetamine-exposed mice
Ejdrup, A. L.; Wellbourne-Wood, J.; Dreyer, J. K.; Guldhammer, N.; Lycas, M. D.; Gether, U.; Hall, B. J.; Soerensen, G.
10.1101/2022.10.27.513984 — neuroscience — Posted on 2022-10-29
302 Highlight Results, Don't Hide Them: Enhance interpretation, reduce biases and improve reproducibility
Taylor, P. A.; Reynolds, R. C.; Calhoun, V.; Gonzalez-Castillo, J.; Handwerker, D. A.; Bandettini, P. A.; Mejia, A. F.; Chen, G.
10.1101/2022.10.26.513929 — neuroscience — Posted on 2022-10-29
303 Optimized detection of allelic imbalances specific for homologous recombination deficiency improves the prediction of clinical outcomes in cancer
Perez-Villatoro, F.; Oikkonen, J.; Casado, J.; Chernenko, A.; Gulhan, D. C.; Tumiati, M.; Li, Y.; Lavikka, K.; Hietanen, S.; Hynninen, J.; Haltia, U.-M.; Tyrmi, J. S.; Laivuori, H.; Konstantinopoulos, P.; Hautaniemi, S.; Kauppi, L.; Farkkila, A.
10.1101/2021.08.19.456809 — cancer biology — Posted on 2022-10-29
305 Peracetyl N-cyclobutanoyl-D-mannosamine enhances expression of sialyl-Lewis X (sLeX / CD15s) and adhesion of leukocytes
Tasneem, A.; Parashar, S.; Aittan, S.; Jain, T.; Chauhan, C.; Rautela, J.; Bhat, Z. A.; Raza, K.; Madhumalar, A.; Sampathkumar, S.-G.
10.1101/2021.12.22.473788 — biochemistry — Posted on 2022-10-29
307 Assessment of Sex Bias in Housekeeping Gene Expression in Adipose Tissue Through the Massive Analysis of Transcriptomics Data
Guaita-Cespedes, M.; Grillo-Risco, R.; Hidalgo, M. R.; Fernandez-Veledo, S.; Burks, D. J.; Gomez-Cabanes, B.; de la Iglesia-Vaya, M.; Galan, A.; Garcia-Garcia, F.
10.1101/2021.12.04.471124 — genomics — Posted on 2022-10-29
311 Heritable changes in chromatin contacts linked to transgenerational obesity
Chang, R. C.; Egusquiza, R. J.; Huang, Y.; Amato, A. A.; Joloya, E. M.; Wheeler, H. B.; Nguyen, A.; Shioda, K.; Odajima, J.; Shioda, T.; Blumberg, B.
10.1101/2022.10.27.514145 — developmental biology — Posted on 2022-10-29
314 AKIR-1 Regulates Proteasome Localization and Function in Caenorhabditis elegans
Pispa, J.; Mikkonen, E.; Arpalahti, L.; Jin, C.; Martinez-Fernandez, C.; Ceron, J.; Holmberg, C. I.
10.1101/2022.10.03.510264 — cell biology — Posted on 2022-10-29
315 Morphological Subprofile Analysis for Bioactivity Annotation of Small Molecules
Pahl, A.; Schoelermann, B.; Rusch, M.; Dow, M.; Hedberg, C.; Nelson, A.; Sievers, S.; Waldmann, H.; Ziegler, S.
10.1101/2022.08.15.503944 — cell biology — Posted on 2022-10-29
316 Intercellular crosstalk in adult dental pulp is mediated by heparin-binding growth factors Pleiotrophin and Midkine
Jiravejchakul, N.; Abe, G. L.; Loza, M.; Park, S.; Matangkasombut, P.; Sasaki, J.-I.; Imazato, S.; Diez, D.; Standley, D. M.
10.1101/2022.10.28.514178 — cell biology — Posted on 2022-10-29
317 Evolutionary Diversification of Methanotrophic Ca. Methanophagales (ANME-1) and Their Expansive Virome
Laso-Perez, R.; Wu, F.; Cremiere, A.; Speth, D. R.; Magyar, J. S.; Krupovic, M.; Orphan, V. J.
10.1101/2022.07.04.498658 — microbiology — Posted on 2022-10-29
318 Inulin prebiotic reinforces host cancer immunosurveillance via γδ T cell activation
Boucher, E.; Plazy, C.; Richard, M. L.; Suau, A.; Mangin, I.; Cornet, M.; Aldebert, D.; Toussaint, B.; Hannani, D.
10.1101/2022.10.13.512019 — immunology — Posted on 2022-10-29
319 Amygdalostriatal transition zone neurons encode sustained valence to direct conditioned behaviors
Mills, F.; Lee, C. R.; Howe, J. R.; Li, H.; Shao, S.; Keisler, M. N.; Lemieux, M. E.; Taschbach, F. H.; Keyes, L. R.; Borio, M. R.; Chen, H. S.; Patel, R. R.; Gross, A. L.; Delahanty, J.; Cazares, C.; Maree, L.; Wichmann, R.; Pereira, T. D.; Benna, M. K.; Root, C. M.; Tye, K. M.
10.1101/2022.10.28.514263 — neuroscience — Posted on 2022-10-29
322 Multiscale cosimulation design template for neuroscience applications
Kusch, L.; Diaz, S.; Klijn, W.; Sontheimer, K.; Bernard, C.; Morrison, A.; Jirsa, V.
10.1101/2022.07.13.499940 — neuroscience — Posted on 2022-10-29
325 Neural representations of the content and production of human vocalization
Voigtlaender, V. A.; Sandhaeger, F.; Hawellek, D. J.; Hage, S. R.; Siegel, M.
10.1101/2022.09.30.510259 — neuroscience — Posted on 2022-10-29
326 A conserved role for stomatin domain genes in olfactory behavior
Liang, X.; Taylor, M.; Napier-Jameson, R.; Calovich-Benne, C.; Norris, A. D.
10.1101/2022.09.26.508537 — neuroscience — Posted on 2022-10-29
327 Highlighter: an optogenetic actuator for light-mediated, high resolution gene expression control in plants
Larsen, B.; Hofmann, R.; Camacho, I. S.; Clarke, R. W.; Lagarias, J. C.; Jones, A. R.; Jones, A. M.
10.1101/2022.10.28.514161 — synthetic biology — Posted on 2022-10-29
331 Deep learning can predict multi-omic biomarkers from routine pathology images: A systematic large-scale study
Arslan, S.; Mehrotra, D.; Schmidt, J.; Geraldes, A.; Singhal, S.; Hense, J.; Li, X.; Bass, C.; Kather, J. N.; Pandya, P.; Raharja-Liu, P.
10.1101/2022.01.21.477189 — cancer biology — Posted on 2022-10-29
334 MetaFun: Unveiling sex differences in multiple omics studies through comprehensive functional meta-analysis
Malmierca-Merlo, P.; Sanchez-Garcia, R.; Grillo-Risco, R.; Perez-Diez, I.; Catala-Senent, J. F.; Gomez-Cabanes, B.; de la Iglesia-Vaya, M.; Hidalgo, M. R.; Garcia-Garcia, F.
10.1101/2021.07.13.451905 — bioinformatics — Posted on 2022-10-29
336 Distinct sequencing success at non-B-DNA motifs
Weissensteiner, M. H.; Cremona, M. A.; Guiblet, W.; Stoler, N.; Harris, R. S.; Cechova, M.; Eckert, K. A.; Chiaromonte, F.; Huang, Y.-F.; Makova, K. D.
10.1101/2022.06.13.495922 — genomics — Posted on 2022-10-29
337 Iterative remodeling of the mouse uterus requires Hedgehog signaling
Roberson, E. C.; Tran, N. K.; Godambe, A.; Rust, T.; Nguimtsop, M.; Mark, H.; Fitch, R.; Wallingford, J. B.
10.1101/2022.10.27.514107 — developmental biology — Posted on 2022-10-29
339 SMbiot: A Shared Latent Model for Microbiomes and their Hosts
Krishnamurthy, M.; Herron, L.; Susanti, D.; Volland-Munson, A.; Plata, G.; Dixit, P. D.
10.1101/2022.10.28.514090 — systems biology — Posted on 2022-10-28
342 Three-dimensional imaging and single-cell transcriptomics of the human kidney implicate perturbation of lymphatics in alloimmunity
Jafree, D. J.; Stewart, B.; Kolatsi-Joannou, M.; Davis, B.; Mitchell, H.; Russell, L. G.; Marinas del Rey, L.; Mason, W. J.; Lee, B. I.; Heptinstall, L.; Pomeranz, G.; Moulding, D.; Wilson, L.; Wickenden, T.; Malik, S.; Holroyd, N.; Walsh, C.; Chandler, J. C.; Cao, K. X.; Winyard, P. J.; Price, K. L.; Busche, M. A.; Walker-Samuel, S.; Scambler, P. J.; Motallebzadeh, R.; Clatworthy, M. R.; Long, D. A.
10.1101/2022.10.28.514222 — immunology — Posted on 2022-10-28
343 A Common Resequencing-Based Genetic Marker Dataset for Global Maize Diversity
Grzybowski, M. W.; Mural, R. V.; Xu, G.; Turkus, J.; Yang, J.; Schnable, J. C.
10.1101/2022.10.28.514203 — plant biology — Posted on 2022-10-28
344 Temporary knockdown of p53 during focal limb irradiation increases the development of sarcomas
Daniel, A. R.; Lee, C.-L.; Su, C.; Williams, N. T.; Li, Z.; Huang, J.; Lopez, O.; Luo, L.; Ma, Y.; Campos, L. D. S.; Selitsky, S. R.; Modliszewski, J. L.; Liu, S.; Mowery, Y. M.; Cardona, D. M.; Kirsch, D. G.
10.1101/2022.10.28.514234 — cancer biology — Posted on 2022-10-28
346 GENLIB: new function to simulate haplotype transmission in large complex genealogies
Rakesh, M.; Vezina, H.; Laprise, C.; Freeman, E.; Burkett, K.; Roy-Gagnon, M.-H.
10.1101/2022.10.28.514245 — bioinformatics — Posted on 2022-10-28
348 In Vitro Toxicity Profile of myblu™ electronic cigarette Aerosol Compared to Cigarette Smoke: the REPLICA project
Emma, R.; Fuochi, V.; Distefano, A.; Rust, S.; Zadjali, F.; Tobi, M. A.; Zadjali, R.; Alharthi, Z.; Pulvirenti, R.; Furneri, P. M.; Polosa, R.; Caruso, M.; Li Volti, G.
10.1101/2022.10.28.514205 — biochemistry — Posted on 2022-10-28
350 A multi-enhancer hub at the Ets1 locus controls T cell differentiation and allergic inflammation through 3D genome topology
Chandra, A.; Yoon, S.; Michieletto, M.; Goldman, N.; Ferrari, E.; Fasolino, M.; Joannas, L.; Kee, B.; Henao-Mejia, J.; Vahedi, G.
10.1101/2022.10.28.514213 — genomics — Posted on 2022-10-28
354 What is an urban bird? Trait-based predictions of urban tolerance for the world's birds are modulated by latitude and human population density
Neate-Clegg, M. H. C.; Tonelli, B. A.; Youngflesh, C.; Wu, J. X.; Montgomery, G. A.; Sekercioglu, C. H.; Tingley, M. W.
10.1101/2022.10.28.514262 — ecology — Posted on 2022-10-28
355 Comprehensive multi-omics characterization of gut microbiome extracellular vesicles reveals a connection to gut-brain axis signaling
Sultan, S.; Yousuf, B.; Yeo, J.; Ahmed, T.; Bouhlel, N. E.; Hassan, H.; Minic, Z.; Mottawea, W.; Hammami, R.
10.1101/2022.10.28.514259 — microbiology — Posted on 2022-10-28
356 A whole blood intracellular cytokine assay optimised for field site studies demonstrates polyfunctionality of CD4+ T cells in acute scrub typhus
Inthawong, M.; Pinthong, N.; Thaiprakhong, A.; Wangrangsimakul, T.; Sunyakumthorn, P.; Hill, J.; Sonthayanon, P.; Paris, D. H.; Dunachie, S.; Kronsteiner, B.
10.1101/2022.10.28.513456 — immunology — Posted on 2022-10-28
357 LTP-like noninvasive striatal brain stimulation enhances striatal activity and motor skill learning in humans
Wessel, M. J.; Beanato, E.; Popa, T.; Windel, F.; Vassiliadis, P.; Menoud, P.; Beliaeva, V.; Violante, I. R.; Abderrahmane, H.; Dzialecka, P.; Park, C.-H.; Maceira-Elvira, P.; Morishita, T.; Cassara, A.; Steiner, M.; Grossman, N.; Neufeld, E.; Hummel, F. C.
10.1101/2022.10.28.514204 — neuroscience — Posted on 2022-10-28
358 Matrix Metalloproteinase Activity During Methamphetamine Cued Relapse
Lewandowski, S. I.; Hodebourg, R.; Wood, S. K.; Carter, J. S.; Nelson, K.; Kalivas, P. W.; Reichel, C. M.
10.1101/2022.10.28.514236 — neuroscience — Posted on 2022-10-28
360 A two-pool mechanism of vesicle release in medial habenula terminals underlies GABAB receptor-mediated potentiation
Koppensteiner, P.; Bhandari, P.; Önal, C.; Borges-Merjane, C.; Le Monnier, E.; Nakamura, Y.; Sadakata, T.; Sanbo, M.; Hirabayashi, M.; Brose, N.; Jonas, P.; Shigemoto, R.
10.1101/2022.10.28.514202 — neuroscience — Posted on 2022-10-28
367 SEMPAI: a Self-Enhancing Multi-Photon Artificial Intelligence for prior-informed assessment of muscle function and pathology
Muehlberg, A.; Ritter, P.; Langer, S.; Goossens, C.; Nuebler, S.; Schneidereit, D.; Taubmann, O.; Denzinger, F.; Noerenberg, D.; Haug, M.; Goldmann, W.; Maier, A.; Friedrich, O.; Kreiss, L.
10.1101/2022.10.28.514253 — bioinformatics — Posted on 2022-10-28
368 Multiscale Hybrid Fabrication: Volumetric Printing Meets Two-Photon Ablation
Rizzo, R.; Ruetsche, D.; Liu, H.; Chansoria, P.; Wang, A.; Hasenauer, A.; Zenobi-Wong, M.
10.1101/2022.10.28.513651 — bioengineering — Posted on 2022-10-28
370 Co-option of the transcription factor SALL1 in mole ovotestis formation
Schindler, M.; Osterwalder, M.; Harabula, I.; Wittler, L.; Tzika, A. C.; Dechmann, D.; Vingron, M.; Visel, A.; Haas, S.; Real, F. M.
10.1101/2022.10.28.514220 — evolutionary biology — Posted on 2022-10-28
371 The gene expression landscape of the human locus coeruleus revealed by single-nucleus and spatially-resolved transcriptomics
Weber, L. M.; Divecha, H. R.; Tran, M. N.; Kwon, S. H.; Spangler, A.; Montgomery, K. D.; Tippani, M.; Bharadwaj, R.; Kleinman, J. E.; Page, S. C.; Hyde, T. M.; Collado-Torres, L.; Maynard, K. R.; Martinowich, K.; Hicks, S. C.
10.1101/2022.10.28.514241 — neuroscience — Posted on 2022-10-28
374 Protein aggregation and calcium dysregulation are the earliest hallmarks of synucleinopathy in human midbrain dopaminergic neurons
Virdi, G. S.; Choi, M. L.; Evans, J. R.; Yao, Z.; Athauda, D.; Strohbuecker, S.; Wernick, A. I.; Alrashidi, H.; Melandri, D.; Perez-lloret, J.; Stroh, P. R.; Sylantyev, S.; Eaton, S.; Heales, S.; Kunath, T.; Horrocks, M. H.; Abramov, A. Y.; Patani, R.; Gandhi, S.
10.1101/2022.10.28.514238 — neuroscience — Posted on 2022-10-28
383 Time of Sample Collection Critical for Microbiome Replicability
Allaband, C.; Lingaraju, A.; Ramos, S. F.; Kumar, T.; Javaheri, H.; Tiu, M. D.; Machado, A. C. D.; Richter, R. A.; Elijah, E.; Haddad, G. G.; Leone, V. A.; Dorrestein, P. C.; Knight, R.; Zarrinpar, A.
10.1101/2022.10.26.513817 — systems biology — Posted on 2022-10-28
386 Bacterial Strategies for Damage Management
Joshi, K.; Gandhi, R.; Krakauer, D.; Iyer-Biswas, S.; Kempes, C. P.
10.1101/2022.10.27.514133 — biophysics — Posted on 2022-10-28
389 RAPTOR: A Five-Safes approach to a secure, cloud native and serverless genomics data repository
Shih, C. C.; Chen, J.; Lee, A. S.; Bertin, N.; Hebrard, M.; Khor, C. C.; Li, Z.; Tan, J. H. J.; Meah, W. Y.; Peh, S. Q.; Mok, S. Q.; Sim, K. S.; Liu, J.; Wang, L.; Wong, E.; Li, J.; Tin, A.; Cheng, C.-Y.; Heng, C.-K.; Yuan, J.-M.; Koh, W.-P.; Saw, S. M.; Friedlander, Y.; Sim, X.; Chai, J. F.; Chong, Y. S.; Davila, S.; Goh, L. L.; Lee, E. S.; Wong, T. Y.; Karnani, N.; Leong, K. P.; Yeo, K. K.; Chambers, J. C.; Goh, R. S. M.; Tan, P.; Dorajoo, R.
10.1101/2022.10.27.514127 — genomics — Posted on 2022-10-28
390 Evaluating metabolic and genomic data for predicting grain traits under high night temperature stress in rice
Bi, Y.; Yassue, R. M.; Paul, P.; Dhatt, B. K.; Sandhu, J.; Do, T. P.; Walia, H.; Obata, T.; Morota, G.
10.1101/2022.10.27.514071 — genetics — Posted on 2022-10-28
395 Multi-omics Analysis Identifies IgG2b Class-Switching with ALCAM-CD6 Co-Stimulation in Lymph Nodes During Advanced Inflammatory-Erosive Arthritis
Kenney, H. M.; Rangel-Moreno, J.; Peng, Y.; Chen, K. L.; Bruno, J.; Embong, A.; Pritchett, E.; Fox, J. I.; Quataert, S.; Muthukrishnan, G.; Wood, R. W.; Korman, B. D.; Anolik, J. H.; Xing, L.; Ritchlin, C. T.; Schwarz, E. M.; Wu, C.-L.
10.1101/2022.10.27.514103 — immunology — Posted on 2022-10-28
397 Drug Reinforcement Impairs Cognitive Flexibility by Inhibiting Striatal Cholinergic Neurons
Gangal, H.; Xie, X.; Cheng, Y.; Wang, X.; Lu, J.; Zhuang, X.; Essoh, A.; Huang, Y.; Smith, L. N.; Smith, R. J.; Wang, J.
10.1101/2022.10.27.514125 — neuroscience — Posted on 2022-10-28
398 Ancestry-related differences in chromatin accessibility and gene expression of APOE4 are associated with Alzheimer disease risk
Celis, K.; Muniz Moreno, M. D.; Rajabli, F.; Whitehead, P.; Hamilton-Nelson, K.; Dykxhoorn, D. M.; Nuytemans, K.; Wang, L.; Dalgard, C. L.; Flanagan, M.; Weintraub, S.; Geula, C.; Gearing, M.; Bennett, D. A.; Schuck, T.; Jin, F.; Pericak-Vance, M. A.; Griswold, A. J.; Young, J. I.; Vance, J. M.
10.1101/2022.10.27.514114 — neuroscience — Posted on 2022-10-28
399 Integrated PET and confocal imaging informs a functional timeline for the dynamic process of vascular reconnection during grafting.
Frank, M.; Komarov, S.; Wang, Q.; Li, K.; Hecking, M.; Fowler, H.; Ravenburg, C.; Widmier, A.; Johnson, A.; Thomas, H.; Coneva, V.; Chitwood, D. H.; Tai, Y.-C.
10.1101/2022.10.27.513862 — plant biology — Posted on 2022-10-28
400 Non-Synonymous, Synonymous, and Non-Coding Nucleotide Variants Contribute to Recurrently Altered Biological Processes During Retinoblastoma Progression
Stachelek, K.; Harutyunyan, N.; Lee, S.; Beck, A.; Kim, J.; Xu, L.; Berry, J.; Nagiel, A.; Reynolds, C. P.; Murphree, A. L.; Lee, T.; Aparicio, J.; Cobrinik, D.
10.1101/2022.10.27.512289 — cancer biology — Posted on 2022-10-28
401 Discovery of prevalent, clinically actionable tumor neoepitopes via integrated biochemical and cell-based platforms
Gurung, H.; Heidersbach, A. J.; Darwish, M.; Chan, P.; Li, J.; Beresini, M.; Zill, O.; Wallace, A.; Tong, A.-J.; Hascall, D.; Torres, E.; Chang, A.; Lou, K.; Abdolazimi, Y.; Uche, U.; Laur, M.; Notturno, R.; Ebert, P. J. R.; Blanchette, C.; Haley, B.; Rose, C. M.
10.1101/2022.10.27.513529 — cancer biology — Posted on 2022-10-28
404 Comparing 10x Genomics single-cell 3' and 5' assay in short-and long-read sequencing
Hsu, J.; Jarroux, J.; Joglekar, A.; Romero, J. P.; Nemec, C.; Reyes, D.; Royall, A.; He, Y.; Belchikov, N.; Leo, K.; Taylor, S. E. B.; Tilgner, H. U.
10.1101/2022.10.27.514084 — bioinformatics — Posted on 2022-10-28
410 Demographically explicit scans for barriers to gene flow using gIMble
Laetsch, D. R.; Bisschop, G.; Martin, S. H.; Aeschbacher, S.; Setter, D.; Lohse, K.
10.1101/2022.10.27.514110 — evolutionary biology — Posted on 2022-10-28
411 Mechanical force induces DRP1-dependent asymmetrical mitochondrial fission for quality control
Liu, X.; Xu, L.; Song, Y.; Li, X.; Wong, C.-Y.; Rong, C.; Feng, J.; Chow, H.-M.; Yao, S.; Gao, S.; Liu, X.; Duan, L.
10.1101/2022.10.27.513965 — cell biology — Posted on 2022-10-28
412 The small non-coding RNA B11 regulates multiple facets of Mycobacterium abscessus virulence
Bar-Oz, M.; Martini, M. C.; Alonso, M. N.; Meir, M.; Lore, N. I.; Miotto, P.; Riva, C.; Xiao, J.; Masiello, C. S.; Misiakou, M.-A.; Sun, H.; Moy, J. K.; Johansen, H. K.; Cirillo, D. M.; Shell, S. S.; Barkan, D.
10.1101/2022.10.27.514065 — microbiology — Posted on 2022-10-28
416 The influence of familiarity on the neural coding of face sex
Foster, C.; Schultz, J.; Munzing, M.; Bülthoff, I.; Armann, R.
10.1101/2022.10.27.514076 — neuroscience — Posted on 2022-10-28
423 Long-Range Hopping Conductivity in Proteins
Krishnan, S.; Aksimentiev, A.; Lindsay, S.; Matyushov, D.
10.1101/2022.10.27.514097 — biophysics — Posted on 2022-10-28
424 Stereochemistry Determines Immune Cellular Responses to Polylactide Implants
Maduka, C. V.; Alhaj, M.; Ural, E.; Kuhnert, M. M.; Habeeb, O. M.; Schilmiller, A. L.; Hankenson, K. D.; Goodman, S. B.; Narayan, R.; Contag, C. H.
10.1101/2022.10.27.514118 — bioengineering — Posted on 2022-10-28
427 Equalizing epigenetically imprinted centromeres in early mammalian embryos
Manske, G.; Jorgensen, K.; Ma, B.; Aboelenain, M.; Tower, C.; Chakraborty, S.; Ranjan, R.; Das, A.; Lampson, M. A.; Black, B. E.; Schindler, K.; Chen, X.; Hammoud, S. S.
10.1101/2022.10.27.514094 — developmental biology — Posted on 2022-10-28
428 The class XIV myosin of Toxoplasma gondii, TgMyoA, is druggable in an animal model of infection
Kelsen, A.; Kent, R. S.; Snyder, A. K.; Wehri, E.; Bishop, S. J.; Stadler, R. V.; Powell, C.; Martorelli di Genova, B.; Rompikuntal, P. K.; Boulanger, M. J.; Warshaw, D. M.; Westwood, N. J.; Schaletzky, J.; Ward, G. E.
10.1101/2022.09.09.507210 — microbiology — Posted on 2022-10-28
429 Natural heteroclitic-like peptides are generated by SARS-CoV-2 mutations
Tiezzi, C.; Vecchi, A.; Rossi, M.; Cavazzini, D.; Bolchi, A.; Laccabue, D.; Sacchelli, L.; Brillo, F.; Meschi, T.; Ticinesi, A.; Nouvenne, A.; Donofrio, G.; Zanelli, P.; Benecchi, M.; Giuliodori, S.; Fisicaro, P.; Montali, I.; Urbani, S.; Pedrazzi, G.; Missale, G.; Telenti, A.; Corti, D.; Ottonello, S.; Ferrari, C.; Boni, C.
10.1101/2022.10.28.513849 — immunology — Posted on 2022-10-28
430 Tocilizumab treatment leads to early resolution of myeloid dysfunction and lymphopenia in patients hospitalized with COVID-19
Shivram, H.; Hackney, J. A.; Rosenberger, C. M.; Teterina, A.; Qamra, A.; Onabajo, O.; McBride, J.; Cai, F.; Bao, M.; Tsai, L.; Regev, A.; Rosas, I.; Bauer, R.
10.1101/2022.10.27.514096 — immunology — Posted on 2022-10-28
431 FrangiPANe, a tool for creating a panreference using left behind reads
Tranchant-Dubreuil, C.; Chenal, C.; Blaison, M.; Albar, L.; Klein, V.; Mariac, C.; Wing, R. A.; Vigouroux, y.; Sabot, F.
10.1101/2022.07.14.499848 — plant biology — Posted on 2022-10-28
432 A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients
Pita-Juarez, Y.; Karagkouni, D.; Kalavros, N.; Melms, J. C.; Niezen, S.; Delorey, T. M.; Essene, A. L.; Brook, O. R.; Pant, D.; Skelton-Badlani, D.; Naderi, P.; Huang, P.; Pan, L.; Hether, T.; Andrews, T. S.; Ziegler, C. G. K.; Reeves, J.; Myloserdnyy, A.; Chen, R.; Nam, A.; Phelan, S.; Liang, Y.; Amin, A. D.; Biermann, J.; Hibshoosh, H.; Veregge, M.; Kramer, Z.; Jacobs, C.; Yalcin, Y.; Phillips, D.; Slyper, M.; Subramanian, A.; Ashenberg, O.; Bloom-Ackermann, Z.; Tran, V. M.; Gomez, J.; Sturm, A.; Zhang, S.; Fleming, S. J.; Warren, S.; Beechem, J.; Hung, D.; Babadi, M.; Padera, R. F.; MacParl
10.1101/2022.10.27.514070 — genomics — Posted on 2022-10-28
437 Daily Artificial Gravity is Associated with Greater Neural Efficiency during Sensorimotor Adaptation
Tays, G.; Hupfeld, K.; McGregor, H.; Beltran, N.; Kofman, I.; DeDios, Y.; Mulder, E.; Bloomberg, J.; Mulavara, A.; Wood, S.; Seidler, R.
10.1101/2022.10.27.514043 — neuroscience — Posted on 2022-10-28
439 SalienceNet: an unsupervised Image-to-Image translation method for nuclei saliency enhancement in microscopy images
Bouilhol, E.; Lefevre, E.; Barry, T.; Levet, F.; Beghin, A.; Viasnoff, V.; Galindo, X.; Galland, R.; Sibarita, J.-B.; Nikolski, M.
10.1101/2022.10.27.514030 — bioinformatics — Posted on 2022-10-28
445 Elevated estradiol during a hormone simulated pseudopregnancy decreases sleep and increases hypothalamic activation in female Syrian hamsters
Irvine, A.; Gaffney, M. I.; Haughee, E. K.; Horton, M. A.; Morris, H. C.; Harris, K. C.; Corbin, J. E.; Merrill, C.; Perlis, M. L.; Been, L. E.
10.1101/2022.10.27.514063 — neuroscience — Posted on 2022-10-28
447 Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-specific Transcriptome and Molecular Subtype
Bahrambeigi, V.; Lee, J. J.; Branchi, V.; Henry, J. T.; Rajapakshe, K. I.; Stephens, B. M.; Dhebat, S.; Hurd, M. W.; Sun, R.; Yang, P.; Wang, W.; Kopetz, S. E.; MAITRA, A.; Guerrero, P. A.
10.1101/2022.10.27.514047 — cancer biology — Posted on 2022-10-28
449 Theta phase specific modulation of hippocampal memory neurons
Rahsepar, B.; Noueihed, J.; Norman, J. F.; Lahner, B.; Quick, M.; Ghaemi, K.; Pandya, A.; Fernandez, F. R.; Ramirez, S.; White, J. A.
10.1101/2022.10.27.513992 — neuroscience — Posted on 2022-10-28
454 Membrane-active peptides escape drug-resistance in cancer
Benfield, A. H.; Vernen, F.; Young, R. S. E.; Bufi, F. N.; Hammerlindl, H.; Craik, D. J.; Schaider, H.; Lawrence, N.; Blanksby, S. J.; Henriques, S. T.
10.1101/2022.10.27.513961 — cancer biology — Posted on 2022-10-28
456 Benchmarking solutions to the T-cell receptor epitope prediction problem: IMMREP22 workshop report
Meysman, P.; Barton, J.; Bravi, B.; Cohen-Lavi, L.; Karnaukhov, V.; Lilleskov, E.; Montemurro, A.; Nielsen, M.; Mora, T.; Pereira, P.; Postovskaya, A.; Rodriguez Martinez, M.; Fernandez-de-Cossio-Diaz, J.; Vujkovic, A.; Walczak, A.; Weber, A.; Yin, R.; Eugster, A.; Sharma, V.
10.1101/2022.10.27.514020 — bioinformatics — Posted on 2022-10-28
458 RecGraph: adding recombinations to sequence-to-graph alignments
Avila Cartes, J.; Bonizzoni, P.; Ciccolella, S.; Della Vedova, G.; Denti, L.; Monti, D.; Pirola, Y.; Porto, F.
10.1101/2022.10.27.513962 — bioinformatics — Posted on 2022-10-28
463 Overruled by nature: A plastic response to an ecological regime shift disconnects a gene and its trait
Besnier, F.; Skaala, O.; Wennevik, V.; Ayllon, F.; Utne, K.; Fjeldheim, P. t.; Andersen, K. C.; Knutar, S.; Glover, K. A.
10.1101/2022.10.27.514021 — genetics — Posted on 2022-10-28
466 Species Richness and Speciation Rates for all Terrestrial Animals Emerge from a Synthesis of Ecological Theories
Fernandes, L. D.; Hintzen, R. E.; Thompson, S. E. D.; Barychka, T.; Tittensor, D.; Harfoot, M.; Newbold, T.; Rosindell, J.
10.1101/2022.10.26.513952 — ecology — Posted on 2022-10-28
467 Gut microbiota assemblages of generalist predators are driven by local- and landscape-scale factors
saqib, H. S. A.; sun, l.; Pozsgai, G.; liang, p.; Goraya, M. U.; Akutse, K. S.; You, M.; Gurr, G. M.; you, s.
10.1101/2022.10.27.513979 — ecology — Posted on 2022-10-28
469 Characterization of undocumented CO2 hydrothermal vents in the Mediterranean Sea: implications for ocean acidification studies
D'Alessandro, M.; Gambi, M. C.; Caruso, C.; Di Bella, M.; Esposito, V.; Gattuso, A.; Giacobbe, S.; Kralj, M.; Italiano, F.; Lazzaro, G.; Sabatino, G.; de Vittor, C.
10.1101/2022.10.27.513997 — ecology — Posted on 2022-10-28
472 ISG15 is required for the dissemination of Vaccinia virus extracellular virions
Becares, M.; Albert, M.; Tarrega, C.; Coloma, R.; Falqui, M.; Luhmann, E.; Radoshevich, L.; Guerra, S.
10.1101/2022.10.27.514002 — immunology — Posted on 2022-10-28
473 A mind-body interface alternates with effector-specific regions in motor cortex
Gordon, E. M.; Chauvin, R. J.; Van, A. N.; Rajesh, A.; Nielsen, A.; Newbold, D. J.; Lynch, C. J.; Seider, N. A.; Krimmel, S. R.; Scheidter, K. M.; Monk, J.; Miller, R. L.; Metoki, A.; Montez, D. F.; Zheng, A.; Elbau, I.; Madison, T.; Nishino, T.; Myers, M. J.; Kaplan, S.; D'Andrea, C. B.; Demeter, D. V.; Feigelis, M.; Barch, D. M.; Smyser, C. D.; Rogers, C. E.; Zimmerman, J.; Botteron, K. N.; Pruett, J. R.; Willie, J. T.; Brunner, P.; Shimony, J. S.; Kay, B. P.; Marek, S.; Norris, S. A.; Gratton, C.; Sylvester, C. M.; Power, J. D.; Liston, C.; Greene, D. J.; Roland, J. L.; Petersen, S. E.; Rai
10.1101/2022.10.26.513940 — neuroscience — Posted on 2022-10-28
475 The endogenous modulation of visual plasticity in human adults
Chen, Y.; Gao, Y.; He, Z.; Sun, Z.; Mao, Y.; Hess, R. F.; Zhang, P.; Zhou, J.
10.1101/2022.10.27.513994 — neuroscience — Posted on 2022-10-28
476 Within-animal comparison of microdialysis and fiber photometry in amphetamine-exposed mice
Ejdrup, A. L.; Wellbourne-Wood, J.; Dreyer, J. K.; Guldhammer, N.; Lycas, M. D.; Gether, U.; Hall, B. J.; Soerensen, G.
10.1101/2022.10.27.513984 — neuroscience — Posted on 2022-10-28
478 Characterisation of organised smooth endoplasmic reticulum suggests a route towards synthetic compartmentalisation
Sandor, A.; Samalova, M.; Brandizzi, F.; Kriechbaumer, V.; Moore, I.; Fricker, M. D.; Sweetlove, L. J.
10.1101/2022.10.27.514093 — plant biology — Posted on 2022-10-28
479 A new gene encoding a cytosolic glutamine synthetase in pine is linked to developing tissues
Valderrama-Martin, J. M.; Ortigosa, F.; Aledo, J. C.; Avila, C.; Canovas, F. M.; Canas, R. A.
10.1101/2022.10.27.514046 — plant biology — Posted on 2022-10-28
483 A deficiency screen of the 3rd chromosome for dominant modifiers of the Drosophila ER integral membrane protein, Jagunal
Ascencio, G.; de Cruz, M. A.; Abuel, J.; Alvarado, S.; Arriaga, Y.; Conrad, E. A.; Castro, A.; Eichelberger, K.; Galvan, L.; Gundy, G.; Inojoza, J. A.; Jimenez, A. D.; Lu, N. T.; Lugar, C.; Marania, R.; Mendsaikhan, T.; Ortega, J.; Nand, N.; Rodrigues, N. S.; Shabazz, K.; Tam, C.; Valenciano, E.; Hayzelden, C.; Eritano, A. S.; Riggs, B.
10.1101/2022.10.26.513935 — genetics — Posted on 2022-10-28
484 Induction of telomerase in p21-positive cells counteracts capillaries rarefaction in aging mice lung
Lipskaia, L.; Breau, M.; Cayrou, C.; Churikov, D.; Braud, L.; Fouillade, C.; Curras-Alonso, S.; Bauwens, S.; Jourquin, F.; Fiore, F.; Castellano, R.; Josselin, E.; Sanchez-Ferrer, C.; Giovinazo, G.; Gilson, E.; Flores, I.; Londono-Vallejo, A.; Adnot, S.; Geli, V.
10.1101/2022.10.27.514005 — molecular biology — Posted on 2022-10-28
485 RIG-I activation primes and trains innate antiviral immune memory
Adamson, M. S.; Nesic, S.; Buness, A.; Bayrak, K.; Schmitz, S.; Soler, S.; Zillinger, T.; Marx, S.; Lambing, S.; Andryka-Cegielski, K.; Khan, F.; Schlee-Guimaraes, T. M.; Herberhold, S.; Proietti, M.; Placek, K.; Reading, P. C.; Cicin-Sain, L.; Schlee, M.; van den Boorn, J.; Hartmann, E.; Hartmann, G.; Bartok, E.
10.1101/2022.10.27.514004 — immunology — Posted on 2022-10-28
489 Prefrontal control of actions in freely moving macaques
Voloh, B.; Maisson, D. J.; Cervera, R. L.; Conover, I.; Zambre, M.; Hayden, B. Y.; Zimmermann, J.
10.1101/2022.10.26.513892 — neuroscience — Posted on 2022-10-28
492 Randomly incorporated genomic 6mA delays zygotic transcription initiation
Febrimarsa, ; Gornik, S.; Bareira, S. N.; Salinas-Saavedra, M.; Schnitzler, C.; Baxevanis, A.; Frank, U.
10.1101/2022.10.27.514014 — developmental biology — Posted on 2022-10-27
493 Activation of an injury-associated transient progenitor state in the epicardium is required for zebrafish heart regeneration
Xia, Y.; Duca, S.; Perder, B.; Dundar, F.; Zumbo, P.; Qiu, M.; Yao, J.; Cao, Y.; Harrison, M. R.; zangi, l.; Betel, D.; Cao, J.
10.1101/2022.10.26.513031 — developmental biology — Posted on 2022-10-28
496 Representational similarity learning reveals a graded multi-dimensional semantic space in the human anterior temporal cortex
Cox, C. R.; Rogers, T. T.; Shimotake, A.; Kikuchi, T.; Kunieda, T.; Miyamoto, S.; Takahashi, R.; Matsumoto, R.; Ikeda, A.; Ralph, M. A. L.
10.1101/2022.10.27.514039 — neuroscience — Posted on 2022-10-27
497 Hexanucleotide repeat expansions in C9orf72 alter microglial responses and prevent a coordinated glial reaction in ALS
Masrori, P.; Bijnens, B.; Davie, K.; Poovathingal, S. K.; Storm, A.; Hersmus, N.; Fumagalli, L.; Van Den Bosch, L.; Fiers, M.; Thal, D. R.; Mancuso, R.; Van Damme, P.
10.1101/2022.10.26.513909 — neuroscience — Posted on 2022-10-27
498 Lipid homeostasis is essential for a maximal ER stress response
Garcia, G.; Zhang, H.; Moreno, S.; Tsui, C. K.; Webster, B. M.; Higuchi-Sanabria, R.; Dillin, A.
10.1101/2022.10.27.513991 — cell biology — Posted on 2022-10-27
501 Urine-based detection of biomarkers indicative of chronic kidney disease in a patient cohort from Ghana
Wruck, W.; Boima, V.; Erichsen, L.; Thimm, C.; Koranteng, T.; Kwakyi, E.; Antwi, S.; Adu, D.; Adjaye, J.
10.1101/2022.10.27.513996 — molecular biology — Posted on 2022-10-27
502 TLR7/8 stress response drives histiocytosis in SLC29A3 disorders
Miyake, K.; Shibata, T.; Sato, R.; Taoka, M.; Saitoh, S.-I.; Komine, M.; Yamaguchi, K.; Goyama, S.; Motoi, Y.; Kitaura, J.; Izawa, K.; Yamauchi, Y.; Tsukamoto, Y.; Ichinohe, T.; Fujita, E.; Hiranuma, R.; Fukui, R.; Furukawa, Y.; Kitamura, T.; Takai, T.; Tojo, A.; Ohtsuki, M.; Ohto, U.; Shimizu, T.; Ozawa, M.; Yoshida, N.; Isobe, T.; Latz, E.; Mukai, K.; Taguchi, T.
10.1101/2022.10.27.513971 — immunology — Posted on 2022-10-27
503 Atypical cortical encoding of speech identifies children with Dyslexia versus Developmental Language Disorder
Araujo, J.; Simons, B. D.; Peter, V.; Mandke, K.; Kalashnikova, M.; Macfarlane, A.; Gabrielczyk, F.; Wilson, A.; Di Liberto, G. M.; Burnham, D.; Goswami, U.
10.1101/2022.10.26.513864 — neuroscience — Posted on 2022-10-27
511 MUC13 negatively regulates tight junction proteins and intestinal epithelial barrier integrity via Protein Kinase C
Segui-Perez, C.; Stapels, D.; Ma, Z.; Su, J.; Passchier, E.; Westendorp, B.; Wu, W.; van Putten, J. P.; Strijbis, K.
10.1101/2022.10.27.513982 — cell biology — Posted on 2022-10-27
513 Mechanism of targeted killing of P. aeruginosa by pyocins SX1 and SX2
Premsuriya, J.; Mosbahi, K.; Atanaskovic, I.; Kleanthous, C.; Walker, D.
10.1101/2022.10.27.514055 — microbiology — Posted on 2022-10-27
514 The functional and structural characterization of Xanthomonas campestris pv. campestris core effector XopP revealed a new kinase activity
Kotsaridis, K.; Michalopoulou, V. A.; Tsakiri, D.; Kotsifaki, D.; Kefala, A.; Koundourakis, N.; Celie, P. H. N.; Kokkinidis, M.; Sarris, P. F.
10.1101/2022.10.27.514000 — microbiology — Posted on 2022-10-27
515 Experimental Diets Dictate the Metabolic Benefits of Lactobacillus Strains in Obesity
Larsen, I. S.; Choi, B. S.- Y.; Foh, B.; Kristensen, N. N.; Ouellette, A.; Haller, R. F.; Olsen, P. B.; Saulnier, D.; Sina, C.; Jensen, B. A. H.; Marette, A.
10.1101/2022.10.27.514016 — microbiology — Posted on 2022-10-27
516 Proliferative Exhausted CD8 T Cells Exacerbate Long-lasting Anti-tumor Effects in Human Papillomavirus Positive Head and Neck Squamous Cell Carcinoma
Cheng, D.; Qiu, K.; Rao, Y.; Mao, M.; Li, L.; Wang, Y.; Song, Y.; Chen, J.; Yi, X.; Shao, X.; Huang, S. H.; Zhang, Y.; Chen, X.; Wu, S.; Yu, S.; Liu, J.; Wang, H.; Peng, X.; Li, D.; Yang, L.; Chen, L.; Ying, Z.; Zheng, Y.; Zheng, M.; Ying, B.; Zeng, X.; Xu, W.; Liu, G.; Chen, F.; Yu, H.; Zhao, Y.; Ren, J.
10.1101/2022.10.27.513993 — immunology — Posted on 2022-10-27
518 Antibody-lectin chimeras for glyco-immune checkpoint blockade
Stark, J. C.; Gray, M. A.; Wisnovsky, S.; Ibarlucea-Benitez, I.; Riley, N. M.; Ribi, M. K.; Lustig, M.; Errington, W. J.; Bruncsics, B.; Sarkar, C. A.; Valerius, T.; Ravetch, J. V.; Bertozzi, C. R.
10.1101/2022.10.26.513931 — biochemistry — Posted on 2022-10-27
519 Neurotrophic and immunomodulatory lanostane triterpenoids from wood-inhabiting Basidiomycota
Hassan, K.; Kemkuignou, B. M.; Kirchenwitz, M.; Wittstein, K.; Rascher, M.; Chepkirui, C.; Matasyoh, J. C.; Decock, C.; Koester, R.; Stradal, T. E. B.; Stadler, M.
10.1101/2022.10.27.513914 — biochemistry — Posted on 2022-10-27
520 Green synthesis of ZnO nanoparticles using Cocos nucifera leaf extract: Characterization, antimicrobial, antioxidant, and photocatalytic activity
Rahman, F.; Patwary, M. A. M.; Siddique, M. A. B.; Bashar, M. S.; Haque, M. A.; Akter, B.; Rashid, R.; Haque, M. A.; Uddin, A. K. M. R.
10.1101/2022.10.27.514023 — biochemistry — Posted on 2022-10-27
522 Mitochondrial dysfunction rapidly modulates the abundance and thermal stability of cellular proteins
Groh, C.; Haberkant, P.; Stein, F.; Filbeck, S.; Pfeffer, S.; Savitski, M. M.; Boos, F.; Herrmann, J. M.
10.1101/2022.10.27.514032 — biochemistry — Posted on 2022-10-27
524 Repurposing the CRISPR-Cas9 System for Targeted Chromatin O-linked β-N- acetylglucosamine Editing
Parker, M. P.; Dias, W. B.; Brautman, W.; Lowe, N.; Fedosyuk, H.; Peterson, K. R.; Slawson, C.
10.1101/2022.10.27.514044 — biochemistry — Posted on 2022-10-27
526 HNRNPH1 regulates the neuroprotective cold-shock protein RBM3 expression through poison exon exclusion
Lin, J. Q.; Khuperkar, D.; Pavlou, S.; Makarchuk, S.; Patikas, N.; Lee, F. C. Y.; Kang, J.; Field, S. F.; Zbiegly, J. M.; Freeman, J. L.; Ule, J.; Metzakopian, E.; Ruepp, M.-D.; Mallucci, G. R.
10.1101/2022.10.27.514062 — molecular biology — Posted on 2022-10-27
527 Translesion DNA synthesis polymerase kappa functions in the nucleolar stress response
Paul, S.; Rebok, A.; Cifani, P.; Paul, A.; Pappin, D.; Huang, T. T.; Spratt, T. E.
10.1101/2022.10.27.513845 — molecular biology — Posted on 2022-10-27
530 Intranasal virus-particle mimicking vaccine enhances SARS-CoV-2 clearance in the Syrian hamster model
Patel, D. R.; Minns, A. M.; Sims, D. G.; Field, C. J.; Kerr, A. E.; Heinly, T.; Luley, E. H.; Rossi, R. M.; Bator, C.; Mostafa, I. M.; Hafenstein, S. L.; Lindner, S. E.; Sutton, T. C.
10.1101/2022.10.27.514054 — immunology — Posted on 2022-10-27
532 One-Step PCR Amplicon Library Construction (OSPALC, version 1)
Ni, J.; Pan, J.; Wang, Y.; Chen, T.; Feng, X.; Li, Y.; Lin, T.; Lynch, M.; Long, H.; Li, W.
10.1101/2022.10.26.511284 — genomics — Posted on 2022-10-27
533 Complex changes in serum protein levels upon recovery from SARS-CoV2 infection
Pushalkar, S.; Wu, S.; Maity, S.; Pressler, M.; Rendleman, J.; Vitrinel, B.; Carlock, M. A.; Ross, T.; Choi, H.; Vogel, C.
10.1101/2022.10.26.513886 — immunology — Posted on 2022-10-27
534 Exploring the potential of using simulation games for engaging with sheep farmers about lameness recognition
Jones, M. L.; Barnish, M.; Hughes, R.; Murray, A.; Mansour, O.; Loni, T.; Vickery, H.; Evans, M. L.; Green, L.; Verdezoto, N.
10.1101/2022.10.26.513828 — scientific communication and education — Posted on 2022-10-27
536 Spatial organization of the 3D genome encodes gene co-expression programs in single cells
Dong, P.; Zhang, S.; Xie, L.; Wang, L.; Lemire, A. L.; Lander, A. D.; Chang, H. Y.; Liu, Z.
10.1101/2022.10.26.513917 — genomics — Posted on 2022-10-27
538 Sensitisation of colonic nociceptors by IL-13 is dependent on JAK and p38 MAPK activity
Barker, K. H.; Higham, J. P.; Pattison, L. A.; Chessell, I. P.; Welsh, F.; Smith, E. S. J.; Bulmer, D. C.
10.1101/2022.10.26.511877 — physiology — Posted on 2022-10-27
542 Taxonomic identification accuracy from BOLD and GenBank databases using over a thousand insect barcodes from Colombia
Baena-Bejarano, N.; Reina, C.; Martinez-Revelo, D. E.; Medina, C. A.; Tovar, E.; Uribe-Soto, S.; Neita-Moreno, J. C.; Gonzalez, M. A.
10.1101/2022.10.26.513939 — molecular biology — Posted on 2022-10-27
551 GPR84-Mediated Signal Transduction Promotes Brown Adipocyte Function
Sun, X.; An, Y. A.; Paschoal, V. A.; de Souza, C. O.; Wang, M.-y.; Vishvanath, L.; Arango, L.; Cobb, A.; Nieto Carrion, J. A.; Kidd, H.; Chen, S.; Li, W.-h.; Gupta, R. K.; Oh, D.
10.1101/2022.10.26.513863 — physiology — Posted on 2022-10-27
552 Single nucleus and spatially resolved intra-tumor subtype heterogeneity in bladder cancer
Lindskrog, S. V.; Schmokel, S. S.; Nordentoft, I.; Lamy, P.; Knudsen, M.; Prip, F.; Strandgaard, T.; Jensen, J. B.; Dyrskjot, L.
10.1101/2022.10.27.513983 — cancer biology — Posted on 2022-10-27
555 Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD)
Deganutti, G.; Pipito, L.; Rujan, R. M.; Weizmann, T.; Griffin, P.; Ciancetta, A.; Moro, S.; Reynolds, C. A.
10.1101/2022.10.26.513870 — bioinformatics — Posted on 2022-10-27
557 Design and characterization of a protein fold switching network
Ruan, B.; He, Y.; Chen, Y.; Choi, E. J.; Chen, Y.; Motabar, D.; Solomon, T.; Simmerman, R.; Kauffman, T.; Gallagher, D. T.; Orban, J. P.; Bryan, P. N.
10.1101/2022.10.26.513944 — biochemistry — Posted on 2022-10-27
570 Human T follicular helper clones seed the germinal center-resident regulatory pool
Le Coz, C.; Oldridge, D. A.; Herati, R. S.; De Luna, N.; Garifallou, J.; Cabrera, E. C.; Belman, J. P.; Pueschl, D.; Silva, L. V.; Knox, A. V. C.; Yoon, S.; Zur, K. B.; Handler, S. D.; Hakonarson, H.; Wherry, E. J.; Gonzalez, M.; Romberg, N.
10.1101/2022.10.26.513910 — immunology — Posted on 2022-10-27
572 Identification of dendritic cell-T cell interactions driving immune responses to food
Canesso, M. C. C.; Castro, T. B.; Nakandakari-Higa, S.; Lockhart, A.; Esterhazy, D.; Reis, B. S.; Victora, G. D.; Mucida, D.
10.1101/2022.10.26.513772 — immunology — Posted on 2022-10-27
575 A non-human primate model with Alzheimer's disease-like pathology induced by hippocampal overexpression of human tau
Jiang, Z.; Wang, J.; Luo, B.; Bai, F.; Qin, Y.; Wei, H.; Zhang, S.; Wei, J.; Ding, G.; Ma, L.; He, S.; Chen, R.; Wang, L.; Xu, H.; Wang, X.; Chen, G.; Lei, W.
10.1101/2022.10.26.513832 — neuroscience — Posted on 2022-10-27
576 Effects of sensorineural hearing loss on formant-frequency discrimination: Measurements and models
Carney, L. H.; Cameron, D. A.; Kinast, K. B.; Feld, C. E.; Schwarz, D. M.; Leong, U.-C.; McDonough, J. M.
10.1101/2022.10.26.513920 — neuroscience — Posted on 2022-10-27
579 Highlight Results, Don't Hide Them: Enhance interpretation, reduce biases and improve reproducibility
Taylor, P. A.; Reynolds, R. C.; Calhoun, V.; Gonzalez-Castillo, J.; Handwerker, D. A.; Bandettini, P. A.; Mejia, A. F.; Chen, G.
10.1101/2022.10.26.513929 — neuroscience — Posted on 2022-10-27
581 Transcription factor HSFA7b controls ethylene signaling and meristem maintenance at the shoot apical meristem during thermomemory
John, S.; Apelt, F.; Kumar, A.; Bents, D.; Annunziata, M. G.; Fichtner, F.; Mueller-Roeber, B.; Olas, J. J.
10.1101/2022.10.26.513826 — plant biology — Posted on 2022-10-27
583 Aligning Distant Sequences to Graphs using Long Seed Sketches
Joudaki, A.; Meterez, A.; Mustafa, H.; Koerkamp, R. G.; Kahles, A.; Raetsch, G.
10.1101/2022.10.26.513890 — bioinformatics — Posted on 2022-10-27
585 A pan-cancer PDX histology image repository with genomic and pathological annotations for deep learning analysis
White, B. S.; Woo, X.; Koc, S.; Sheridan, T.; Neuhauser, S. B.; Wang, S.; Evrard, Y. A.; Landua, J. D.; Mashl, R. J.; Davies, S. R.; Fang, B.; Raso, M. G.; Evans, K. W.; Bailey, M. H.; Chen, Y.; Xiao, M.; Rubinstein, J.; Foroughi pour, A.; Dobrolecki, L. E.; Fujita, M.; Fujimoto, J.; Xiao, G.; Fields, R. C.; Mudd, J. L.; Xu, X.; Hollingshead, M. G.; Jiwani, S.; PDXNet Consortium, ; Davis-Dusenbery, B.; Wallace, T. A.; Moscow, J. A.; Doroshow, J. H.; Mitsiades, N.; Kaochar, S.; Pan, C.-x.; Chen, M. S.; Carvajal-Carmona, L. G.; Welm, A. L.; Welm, B. E.; Govindan, R.; Li, S.; Davies, M. A.; Roth
10.1101/2022.10.26.512745 — bioinformatics — Posted on 2022-10-27
586 A Numerical Method to Compute Brain Injury Associated with Concussion
Bastien, C.; Scattina, A.; Neal-Sturgess, C. E.; Panno, R.; Shrinivas, V.
10.1101/2022.10.26.513868 — bioengineering — Posted on 2022-10-27
588 The function and decline of the female reproductive tract at single-cell resolution
Winkler, I.; Tolkachov, A.; Lammers, F.; Lacour, P.; Schneider, N.; Koch, M.-L.; Panten, J.; Gruenschlaeger, F.; Daugelaite, K.; Poth, T.; Haas, S.; Odom, D.; Goncalves, A.
10.1101/2022.10.26.513823 — genomics — Posted on 2022-10-27
589 GoldRush: A de novo long read genome assembler with linear time complexity
Wong, J.; Coombe, L.; Nikolic, V.; Zhang, E.; Nip, K. M.; Sidhu, P.; Warren, R. L.; Birol, I.
10.1101/2022.10.25.513734 — genomics — Posted on 2022-10-27
596 Visual awareness during the attentional blink is determined by representational similarity
Tang, M. F.; Shapiro, K. L.; Enns, J. T.; Visser, T. A. W.; Mattingley, J. B.; Arabzadeh, E.
10.1101/2022.10.25.513789 — neuroscience — Posted on 2022-10-27
598 Gradual cerebral hypoperfusion in a knock-in mouse model of Alzheimer's disease triggers cortical network dysfunctions
Singh, S.; Lacoursiere, S. G.; Mehla, J.; Nazari, M.; Sutherland, R. J.; McDonald, R. J.; Mohajerani, M. H.
10.1101/2022.10.25.513783 — neuroscience — Posted on 2022-10-27
599 Optogenetic manipulation of second messengers in neurons and cardiomyocytes with microbial rhodopsins and adenylyl cyclase
Hagio, H.; Hosaka, S.; Koyama, W.; Song, A. D.; Narantsatsral, J.; Matsuda, K.; Shimizu, T.; Hososhima, S.; Tsunoda, S. P.; Kandori, H.; Hibi, M.
10.1101/2022.10.25.513731 — neuroscience — Posted on 2022-10-27
601 Homotopic local-global parcellation of the human cerebral cortex from resting-state functional connectivity
Yan, X.; Kong, R.; Xue, A.; Yang, Q.; Orban, C.; An, L.; Holmes, A. J.; Qian, X.; Chen, J.; Zuo, X.-N.; Zhou, J. H.; Fortier, M. V.; Tan, A. P.; Gluckman, P.; Chong, Y. S.; Meaney, M.; Bzdok, D.; Eickhoff, S. B.; Yeo, B. T. T.
10.1101/2022.10.25.513788 — neuroscience — Posted on 2022-10-27
606 The temporal regulation inter-leaves from domesticated-tomato contrasts with timelessness of its wild ancestors
Siqueira, J. A.; Martins, A.; Wakin, T.; Silva, M. F.; Batista-Silva, W.; Brito, F.; Fernie, A. R.; Nunes-Nesi, A.; Araujo, W. L.
10.1101/2022.10.25.513690 — plant biology — Posted on 2022-10-27
608 A Unified Modular Framework to Incorporate Structural Dependency in Spatial Omics Data
Su, J.; Reynier, J.-B.; Fu, X.; Zhong, G.; Jiang, J.; Supo Escalante, R.; Wang, Y.; Izar, B.; Knowles, D. A.; Rabadan, R.
10.1101/2022.10.25.513785 — bioinformatics — Posted on 2022-10-27
610 A Robust Bayesian Approach to Bulk Gene Expression Deconvolution withNoisy Reference Signatures
Ghaffari, S.; Bouchonville, K. J.; Saleh, E.; Schmidt, R. E.; Offer, S. M.; Sinha, S.
10.1101/2022.10.25.513800 — bioinformatics — Posted on 2022-10-27
611 Multi-Mode Fiber-Based Speckle Contrast Optical Spectroscopy: Analysis of Speckle Statistics
Lin, C.-H. P.; Orukari, I.; Tracy, C.; Frisk, L. K.; Verma, M.; Chetia, S.; Durduran, T.; Trobaugh, J. W.; Culver, J. P.
10.1101/2022.10.25.513089 — bioengineering — Posted on 2022-10-27
614 A contamination focused approach for optimizing thesingle-cell RNA-seq experiment
Arceneaux, D.; Chen, Z.; Simmons, A.; Heiser, C. N.; Southard-Smith, A. N.; Brenan, M.; Yang, Y.; Chen, B.; Xu, Y.; Choi, E.; Campbell, J. D.; Liu, Q.; Lau, K.
10.1101/2022.10.25.513758 — genomics — Posted on 2022-10-27
616 Identification of plant-derived microRNAs in human kidney
Chen, X.; Xie, X.; Liu, L.; Chen, H.; Wang, B.; Li, Z.; Zeng, L.; Timko, M.; Chen, J.; Lin, W.; Fan, L.
10.1101/2022.10.25.513797 — genetics — Posted on 2022-10-27
617 In Silico Analysis of Novel VHL Germline Mutations in Iranian RCH Patients
Naseripour, M.; Bagherzade, K.; Khakpoor, G.; Sedaghat, A.; Mirshahi, R.; Kasraee, H.; Kiaee, R. A.; Azimi, F.
10.1101/2022.10.26.513811 — genetics — Posted on 2022-10-27
618 Optimizing and benchmarking polygenic risk scores with GWAS summary statistics
Zhao, Z.; Gruenloh, T.; Wu, Y.; Sun, Z.; Miao, J.; Wu, Y.; Song, J.; Lu, Q.
10.1101/2022.10.26.513833 — genetics — Posted on 2022-10-27
621 Natural hybridisation reduces vulnerability to climate change
Brauer, C.; Sandoval-Castillo, J. B.; Gates, K.; Hammer, M.; Unmack, P.; Bernatchez, L.; Beheregaray, L. B.
10.1101/2022.10.25.513775 — evolutionary biology — Posted on 2022-10-27
624 Lymph node expansion predicts magnitude of vaccine immune response
Najibi, A. J.; Lane, R. S.; Sobral, M. C.; Freedman, B. R.; Estupinan, J. G.; Elosegui-Artola, A.; Tringides, C. M.; Dellacherie, M. O.; Williams, K.; Müller, S.; Turley, S. J.; Mooney, D. J.
10.1101/2022.10.25.513749 — immunology — Posted on 2022-10-27
625 Optogenetic manipulation of Gq-and Gi/o-coupled receptor signaling in neurons and heart muscle cells
Hagio, H.; Koyama, W.; Hosaka, S.; Song, A. D.; Narantsatsral, J.; Matsuda, K.; Sugihara, T.; Shimizu, T.; Koyanagi, M.; Terakita, A.; Hibi, M.
10.1101/2022.10.25.513732 — neuroscience — Posted on 2022-10-27
626 Decision and response monitoring during working memory are sequentially represented in the human insula
Llorens, A.; Bellier, L.; Blenkmann, A. O.; Ivanovic, J.; Larsson, P. G.; Lin, J. J.; Endestad, T.; Solbakk, A.-K.; Knight, R. T.
10.1101/2022.10.25.513764 — neuroscience — Posted on 2022-10-27
629 A high-throughput 3D cantilever array to model airway smooth muscle hypercontractility in asthma
Beri, P.; Plunkett, C.; Barbara, J.; Shih, C.-c.; Barnes, S. W.; Ross, O.; Choconta, P.; Trinh, T.; Litvin, B.; Walker, J.; Qiu, M.; Hammack, S.; Toyama, E.
10.1101/2022.10.25.513767 — bioengineering — Posted on 2022-10-27
634 Accurate detection and identification of insects from camera trap images with deep learning
Bjerge, K.; Alison, J.; Dyrmann, M.; Frigaard, C. E.; Mann, H. M. R.; Hoye, T. T.
10.1101/2022.10.25.513484 — ecology — Posted on 2022-10-27
637 Functional geometry of auditory cortical resting state networks derived from intracranial electrophysiology
Banks, M. I.; Krause, B. M.; Berger, D. G.; Campbell, D. I.; Boes, A. D.; Bruss, J. E.; Kovach, C. K.; Kawasaki, H.; Steinschneider, M.; Nourski, K. V.
10.1101/2022.02.06.479292 — neuroscience — Posted on 2022-10-27
638 Gating interactions steer loop conformational changes in the active site of the L1 metallo-β-lactamase
Zhao, Z.; Shen, X.; Chen, S.; Gu, J.; Wang, H.; Mojica, M. F.; Samanta, M.; Bhowmik, D.; Vila, A. J.; Bonomo, R. A.; Haider, S.
10.1101/2022.10.25.513716 — biophysics — Posted on 2022-10-27
639 Structural insight into the stabilization of microtubules by taxanes
Prota, A. E.; Lucena-Agell, D.; Ma, Y.; Estevez-Gallego, J.; Li, S.; Bargsten, K.; Josa-Prado, F.; Andreu, J. M.; Altmann, K.-H.; Gaillard, N.; Kamimura, S.; Muehlethaler, T.; Oliva, M. A.; Steinmetz, M. O.; Fang, W.-S.; Diaz, J. F.
10.1101/2021.07.20.453061 — biophysics — Posted on 2022-10-27
640 Phosphate Starvation Signaling Increases Mitochondrial Membrane Potential through Respiration-independent Mechanisms
Ouyang, Y.; Cunningham, C. N.; Berg, J. A.; Toshniwal, A. G.; Hughes, C. E.; Van Vranken, J. G.; Jeong, M.-Y.; Cluntun, A. A.; Lam, G.; Winter, J. M.; Akdogan, E.; Dove, K. K.; Gygi, S. P.; Dunn, C. D.; Winge, D. R.; Rutter, J.
10.1101/2022.10.25.513802 — cell biology — Posted on 2022-10-27
642 An integrated cell barcoding and computational analysis pipeline for scalable analysis of differentiation at single-cell resolution
Shen, S.; Werner, T.; Sun, Y.; Shim, W. J.; Lukowski, S.; Andersen, S.; Chiu, H. S.; Xia, D.; Pham, D.; Su, Z.; Kim, D.; Yang, P.; Chen, X.; Tan, M. C.; Powell, J. E.; Tam, P. P. L.; Boden, M.; Ho, J. W. K.; Nguyen, Q.; Palpant, N. J.
10.1101/2022.10.12.511862 — genomics — Posted on 2022-10-27
644 Promoter sequence and architecture determine expression variability and confer robustness to genetic variants
Einarsson, H.; Salvatore, M.; Vaagenso, C.; Alcaraz, N.; Bornholdt Lange, J.; Rennie, S.; Andersson, R.
10.1101/2021.10.29.466407 — genomics — Posted on 2022-10-27
647 Disparate patterns of genetic divergence in three widespread corals across a pan-Pacific environmental gradient highlights species-specific adaptation trajectories.
Hume, B. C. C.; Voolstra, C. R.; Armstrong, E.; Mitushasi, G.; Porro, B.; Oury, N.; Agostini, S.; Boissin, E.; Poulain, J.; Carradec, Q.; Paz-Garcia, D. A.; Zoccola, D.; Magalon, H.; Moulin, C.; Bourdin, G.; Iwankow, G.; Romac, S.; Banaigs, B.; Boss, E.; Bowler, C.; de Vargas, C.; Douville, E.; Flores, M.; Furla, P.; Galand, P. E.; Gilson, E.; Lombard, F.; Pesant, S.; Reynaud, S.; Sullivan, M. B.; Shinichi, S.; Thomas, O.; Trouble, R.; Vega Thurber, R.; Wincker, P.; Planes, S.; Allemand, D.; Forcioli, D.
10.1101/2022.10.13.512013 — genetics — Posted on 2022-10-27
648 Epistasis between promoter activity and coding mutations shapes gene evolvability
Caballero, A. F. C.; Gagnon-Arsenault, I.; Dube, A. K.; Despres, P. C.; Kumar, P.; Lafontaine, K.; Pelletier, J. N.; Landry, C. R.
10.1101/2022.06.07.495002 — evolutionary biology — Posted on 2022-10-27
651 Tup1 is Critical for Transcriptional Repression in Quiescence in S. cerevisiae
Bailey, T. B.; Whitty, P. A.; Selker, E. U.; McKnight, J. N.; McKnight, L. E.
10.1101/2022.08.10.503497 — molecular biology — Posted on 2022-10-27
652 Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity
Rinaldi, C.; Waters, C. S.; Kumbier, K.; Rao, L.; Nichols, R. J.; Jacobson, M. P.; Wu, L. F.; Altschuler, S. J.
10.1101/2022.10.25.513743 — systems biology — Posted on 2022-10-27
653 Reclassification of probiotic Lactobacillus acidophilus NCIMB 30184 as Lactobacillus helveticus and Lactobacillus casei NCIMB 30185 as Lacticaseibacillus paracasei
Rodenes, A.; Casinos Ramo, B.; Alvarez Perez, B.; Martinez Blanch, J. F.; Vijayakumar, V.; Superti, G.; Day, R.; Chenoll Cuadros, E. M.
10.1101/2022.10.17.512536 — microbiology — Posted on 2022-10-27
654 Tumor-educated Gr1+CD11b+ cells instigate breast cancer metastasis by twisting cancer cells plasticity via OSM/IL6-JAK signaling
Peyvandi, S.; Bulliard, M.; Kauzlaric, A.; Coquoz, O.; Huang, Y.-t.; Duffey, N.; Gafner, L.; Lorusso, G.; Fournier, N.; Lan, Q.; Rüegg, C.
10.1101/2022.10.26.513889 — cancer biology — Posted on 2022-10-27
655 A PTP1B-Cdk3 signaling axis promotes cell cycle progression of human glioblastoma cells through an Rb-E2F dependent pathway
Villamar-Cruz, O.; Loza-Mejia, M. A.; Vivar-Sierra, A.; Saldivar-Ceron, H. I.; Patino-Lopez, G.; Olguin, J. E.; Terrazas, L. I.; Armas-Lopez, L.; Avila-Moreno, F.; Saha, S.; Chernoff, J.; Camacho-Arroyo, I.; Arias-Romero, L. E.
10.1101/2022.06.14.496178 — cancer biology — Posted on 2022-10-27
656 Novel EGFR-Mutant Mouse Models of Lung Adenocarcinoma Reveal Adaptive Immunity Requirement for Durable Osimertinib Response
Heasley, L. E.; Kleczko, E. K.; Le, A. T.; Hinz, T. K.; Nguyen, T. T.; Navarro, A.; Hu, C.-J.; Clambey, E. T.; Merrick, D. T.; Weiser-Evans, M.; Nemenoff, R. A.
10.1101/2022.10.26.513856 — cancer biology — Posted on 2022-10-27
658 Disrupting peroxisomes alters lipid metabolism in melanoma and uncovers a novel therapeutic vulnerability in combination with MAPK-targeted therapies
Huang, F.; Cai, F.; Dahabieh, M. S.; Gunawardena, K.; Talebi, A.; Dehairs, J.; El-Turk, F.; Park, J. Y.; Goncalves, C.; Gagnon, N.; Su, J.; Gaub, P.; Joyal, J.-S.; Mitchell, J. J.; Swinnen, J. V.; Miller, W. H.; del Rincon, S. V.
10.1101/2022.10.25.513718 — cancer biology — Posted on 2022-10-27
659 HY5 Regulates GLK and GNC Transcription Factors to Orchestrate Photomorphogenesis in Arabidopsis thaliana
Zhang, T.; Zhang, R.; Zeng, X.; Ye, L.; Tian, S.; Zhang, Y.; Zhou, W. B.; Zhu, X.-G.; Wang, P.
10.1101/2022.09.30.510343 — plant biology — Posted on 2022-10-27
663 A mathematical model of calcium signals around laser-induced epithelial wounds
Stevens, A. C.; O'Connor, J. T.; Pumford, A. D.; Page-McCaw, A.; Hutson, M. S.
10.1101/2022.08.24.505161 — biophysics — Posted on 2022-10-27
664 PIEZO1 discriminates mechanical stimuli
Ozkan, A. D.; Wijerathne, T. D.; Gettas, T.; Lacroix, J. J.
10.1101/2022.06.23.497409 — biophysics — Posted on 2022-10-27
665 Calcitic prisms of the giant seashell Pinna nobilis form light guide arrays
Amini, S.; Zhu, T.; Biswas, A.; Charsooghi, M. A.; Kim, K.; Reber, S.; Dauphin, Y.; Fratzl, P.
10.1101/2022.10.25.513698 — biophysics — Posted on 2022-10-27
666 JINXED: Just in time crystallization for easy structure determination of biological macromolecules
Henkel, A.; Galchenkova, M.; Maracke, J.; Yefanov, O.; Hakanpaeae, J.; Mesters, J. R.; Chapman, H. N.; Oberthuer, D.
10.1101/2022.10.26.513656 — biophysics — Posted on 2022-10-27
673 Bark beetles locate fungal symbionts by detecting volatile fungal metabolites of host tree resin monoterpenes
Kandasamy, D.; Zaman, R.; Nakamura, Y.; Zhao, T.; Hartmann, H.; Andersson, M. N.; Hammerbacher, A.; Gershenzon, J.
10.1101/2021.07.03.450988 — ecology — Posted on 2022-10-27
674 Estimating global variation in the maximum growth rates of eukaryotic microbes from cultures and metagenomes via codon usage patterns
Weissman, J.; Dimbo, E.-R. O.; Krinos, A. I.; Neely, C.; Yagues, Y.; Nolin, D.; Hou, S.; Laperriere, S.; Caron, D. A.; Tully, B. L.; Alexander, H.; Fuhrman, J. A.
10.1101/2021.10.15.464604 — microbiology — Posted on 2022-10-27
675 RALF peptides modulate immune response in the moss Physcomitrium patens
Mamaeva, A.; Lyapina, I.; Knyazev, A.; Golub, N.; Mollaev, T.; Chudinova, E.; Elansky, S.; Babenko, V.; Veselovsky, V.; Klimina, K.; Gribova, T.; Kharlampieva, D.; Lazarev, V.; Fesenko, I.
10.1101/2022.10.21.513210 — plant biology — Posted on 2022-10-27
677 The role of clearance in neurodegenerative diseases
Brennan, G. S.; Thompson, T. B.; Oliveri, H.; Rognes, M. E.; Goriely, A.
10.1101/2022.03.31.486533 — neuroscience — Posted on 2022-10-27
678 Adversarial Attacks on Protein Language Models
Carbone, G.; Cuturello, F.; Bortolussi, L.; Cazzaniga, A.
10.1101/2022.10.24.513465 — bioinformatics — Posted on 2022-10-27
679 Inferring cell diversity in single cell data using consortium-scale epigenetic data as a biological anchor for cell identity
Sun, Y.; Shim, W. J.; Shen, S.; Sinniah, E.; Pham, D.; Su, Z.; Mizikovsky, D.; White, M. D.; Ho, J. W. K.; Nguyen, Q.; Boden, M.; Palpant, N. J.
10.1101/2022.10.12.512003 — bioinformatics — Posted on 2022-10-27
680 Heterogeneity in the gene regulatory landscape of leiomyosarcoma.
Belova, T.; Biondi, N.; Hsieh, P.-H.; Lutsik, P.; Chudasama, P.; Kuijjer, M. L.
10.1101/2022.04.13.488196 — bioinformatics — Posted on 2022-10-27
682 Non-triplet genetic code in Euplotes ciliates is a result of neutral evolution
Gaydukova, S. A.; Moldovan, M. A.; Vallesi, A.; Heaphy, S.; Atkins, J. F.; Gelfand, M. S.; Baranov, P.
10.1101/2022.10.12.511967 — evolutionary biology — Posted on 2022-10-27
685 E2 ubiquitin conjugase Bendless is essential for PINK1-Park activity to regulate Mitofusin under mitochondrial stress
Cheramangalam, R. N.; Anand, T.; Pandey, P.; Balasubramaniyan, D.; Varghese, R.; Singhal, N.; Jaiswal, S. N.; Jaiswal, M.
10.1101/2022.10.24.513457 — cell biology — Posted on 2022-10-27
690 Subtilases turn on pectin methylesterase activity for a robust apoplastic immunity
Coculo, D.; Del Corpo, D.; Martinez, M. O.; Vera, P.; Piro, G.; De Caroli, M.; Lionetti, V.
10.1101/2022.07.28.501549 — plant biology — Posted on 2022-10-27
691 Chinese fir genome and the evolution of gymnosperms
Lin, S.-Z.; Chen, Y.; Wu, C.; Sun, W.-H.; Li, Z.; Chen, H.; Wang, J.; Ji, C.; Li, S.-B.; Wang, Z.-W.; Tsai, W.-C.; Ma, X.-Q.; Lan, S.-R.; Zhang, F.-P.; Xie, Y.-C.; Yao, L.; Zhang, Y.; Lv, M.-M.; Zhang, J.-J.; Zhang, D.-Y.; Ye, Y.-Q.; Yu, X.; Xu, S.-S.; Ma, Z.-H.; Ding, G.-C.; Cao, G.-Q.; He, Z.-M.; Wu, P.-F.; Lin, K.-M.; Liu, A.-Q.; Lin, Y.-Q.; Ruan, S.-N.; Liu, B.; Cao, S.-J.; Zhou, L.-L.; Li, M.; Shuai, P.; Hou, X.-L.; Wu, Y.-H.; Li, N.; Xiong, S.; Hao, Y.; Zhou, Z.; Liu, X.-D.; Zuo, D.-D.; Li, J.; Wang, P.; Zhang, J.; Liu, D.-K.; Chen, G.-Z.; Huang, J.; Huang, M.-Z.; Li, Y.; Zheng, Q.; Zhao
10.1101/2022.10.25.513437 — genomics — Posted on 2022-10-26
693 OVGP1 is an oviductal fluid factor essential particularly for early embryonic development in golden hamsters
Yamatoya, K.; Kurosawa, M.; Hirose, M.; Miura, Y.; Taka, H.; Nakano, T.; Hasegawa, A.; Kagami, K.; Yoshitake, H.; Goto, K.; Ueno, T.; Fujiwara, H.; Shinkai, Y.; Kan, F. W. K.; Ogura, A.; Araki, Y.
10.1101/2022.10.25.513711 — developmental biology — Posted on 2022-10-27
694 Pleiotropic effects of BAFF on the senescence-associated secretome and growth arrest
Rossi, M.; Anerillas, C.; Idda, M. L.; Munk, R.; Shin, C. H.; Donega, S.; Tsitsipatis, D.; Herman, A. B.; Martindale, J. L.; Yang, X.; Piao, Y.; Mazan-Mamczarz, K.; Fan, J.; Ferrucci, L.; De, S.; Abdelmohsen, K.; Gorospe, M.
10.1101/2022.10.25.513730 — cell biology — Posted on 2022-10-27
696 Closed genomes uncover a saltwater species of Candidatus Electronema and shed new light on the boundary between marine and freshwater cable bacteria
Sereika, M.; Petriglieri, F.; Jensen, T. B. N.; Sannikov, A.; Hoppe, M.; Nielsen, P. H.; Marshall, I. P. G.; Schramm, A.; Albertsen, M.
10.1101/2022.10.26.513921 — microbiology — Posted on 2022-10-26
697 The protist ubiquitin ligase effector PbE3-2 targets RD21A to impede plant immunity
Chen, T.; Li, C.; Luo, S.; Feng, L.; Wang, Q.; Cheng, J.; Xie, J.; Lin, Y.; Fu, Y.; Jiang, D.
10.1101/2022.10.26.513834 — microbiology — Posted on 2022-10-26
698 CXCL4 signaling and gene induction in human monocytes involve a TLR4 response divergent from LPS
YANG, C.; Yuan, R.; Mishra, B.; Bill, R. D.; Zhang, Y.; Du, Y.; Ah Kioon, M. D.; Barrat, F. J.; Ivashkiv, L. B.
10.1101/2022.10.26.513860 — immunology — Posted on 2022-10-26
699 SETD2 safeguards the genome against isochromosome formation
Mason, F.; Kounlavong, E. S.; Tebeje, A. T.; Dahiya, R.; Guess, T.; Vlach, L.; Norris, S. R.; Lovejoy, C. A.; Dere, R.; Ohi, R.; Ly, P.; Walker, C. L.; Rathmell, W. K.
10.1101/2022.10.25.513694 — cancer biology — Posted on 2022-10-26
705 Fast and versatile sequence-independent protein docking for nanomaterials design using RPXDock
Sheffler, W.; Yang, E. C.; Dowling, Q.; Hsia, Y.; Fries, C. N.; Stanislaw, J.; Langowski, M.; Brandys, M.; Khmelinskaia, A.; King, N. P.; Baker, D.
10.1101/2022.10.25.513641 — bioengineering — Posted on 2022-10-26
707 Multi-species analysis of inflammatory response elements reveals ancient and lineage-specific contributions of transposable elements to NF-κB binding
Wang, L.; Alizada, A.; Rathnakumar, K.; Khyzha, N.; Taylor, T.; Campitelli, L.; Patel, Z. M.; Antounians, L.; Hughes, T.; Roy, S.; Mitchell, J. A.; Fish, J. E.; Wilson, M. D.
10.1101/2022.10.25.513724 — genomics — Posted on 2022-10-26
708 Examining the early distribution of the artemisinin-resistant Plasmodium falciparum kelch13 R561H mutation in Rwanda
Kirby, R.; Giesbrecht, D.; Karema, C.; Watson, O.; Lewis, S.; Munyaneza, T.; Butera, J. d. D.; Juliano, J.; Bailey, J.; Mazarati, J. B.
10.1101/2022.10.26.513523 — genomics — Posted on 2022-10-26
711 The functional impact of 1,570 SNP-accessible missense variants in human OTC
Lo, R. S.; Cromie, G. A.; Tang, M.; Teng, K.; Owens, K.; Sirr, A.; Kutz, J. N.; McLaughlin, R. N.; Morizono, H.; Caldovic, L.; Mew, N. A.; Gropman, A.; Dudley, A. M.
10.1101/2022.10.26.513893 — genetics — Posted on 2022-10-26
712 Targeting IRS-1/2 in uveal melanoma inhibits in vitro cell growth, survival and migration, and in vivo tumor growth.
chattopadhyay, c.; Bhattacharya, R.; Roszik, J.; Khan, F.; Wells, G. A.; Villanueva, H.; Qin, Y.; Bhattacharya, R.; Patel, S.; Grimm, E. A.
10.1101/2022.10.26.513928 — cell biology — Posted on 2022-10-26
713 ASO targeting temperature-controlled RBM3 poison exon splicing prevents neurodegeneration in vivo
Preussner, M.; Smith, H. L.; Zhang, M.; Hughes, D.; Emmerichs, A.-K.; Scalzitti, S.; Peretti, D. A.; Swinden, D.; Neumann, A.; Haltenhof, T.; Mallucci, G. R.; Heyd, F.
10.1101/2022.10.26.513170 — molecular biology — Posted on 2022-10-26
715 Genomic Changes During the Evolution of the Coxiella Genus Along the Parasitism-Mutualism Continuum.
Santos-Garcia, D.; Morel, O.; Henri, H.; El Filali, A.; Buysse, M.; Noël, V.; McCoy, K. D.; Gottlieb, Y.; Klasson, L.; Zenner, L.; Duron, O.; Vavre, F.
10.1101/2022.10.26.513839 — microbiology — Posted on 2022-10-26
720 Augmenting CAR NK cell Anti-tumor Activity by Synapse Tuning
Chockley, P.; Ibanez, J.; Krenciute, G.; Talbot, L.; Gottschalk, S.
10.1101/2022.10.26.512898 — immunology — Posted on 2022-10-26
721 Role of 14-3-3 proteins in human cardiac sodium channel Nav1.5 regulation
Iamshanova, O.; Hämmerli, A.-F.; Ramaye, E.; Seljmani, A.; Ross-Kaschitza, D.; Schärz, N.; Essers, M.; Guichard, S.; Rougier, J.-S.; Abriel, H.
10.1101/2022.10.26.513875 — biophysics — Posted on 2022-10-26
722 Tropomyosin 1-I/C co-ordinates kinesin-1 and dynein motors during oskar mRNA transport
Heber, S.; McClintock, M. A.; Simon, B.; Hennig, J.; Bullock, S. L.; Ephrussi, A.
10.1101/2022.10.26.513919 — biochemistry — Posted on 2022-10-26
724 Dissecting the genetic architecture of sunflower head diameter using genome-wide association study
Delen, Y.; Mural, R. V.; XU, G.; Palali Delen, S.; Schnable, J. C.; Yang, J.; Dweikat, I.
10.1101/2022.10.24.513623 — genomics — Posted on 2022-10-26
725 Extreme genome diversity and cryptic speciation in a harmful algal bloom forming eukaryote
Wisecaver, J. H.; Auber, R. P.; Pendleton, A. L.; Watervoort, N. F.; Fallon, T. R.; Riedling, O. L.; Moore, B. S.; Driscoll, W. W.
10.1101/2022.10.25.513657 — evolutionary biology — Posted on 2022-10-26
726 Consistent Under-reporting of Task Details in Motor Imagery Research
Van Caenegem, E. E.; Hamoline, G.; Waltzing, B. M.; Hardwick, R. M.
10.1101/2022.10.25.513501 — neuroscience — Posted on 2022-10-26
727 Ratio-based quantitative multiomics profiling using universal reference materials empowers data integration
Zheng, Y.; Liu, Y.; Yang, J.; Dong, L.; Zhang, R.; Tian, S.; Yu, Y.; Ren, L.; Hou, W.; Zhu, F.; Mai, Y.; Han, J.; Zhang, L.; Jiang, H.; Lin, L.; Lou, J.; Li, R.; Lin, J.; Liu, H.; Kong, Z.; Wang, D.; Dai, F.; Bao, D.; Cao, Z.; Chen, Q.; Chen, Q.; Chen, X.; Gao, Y.; Jiang, H.; Li, B.; Li, B.; Li, J.; Liu, R.; Qing, T.; Shang, E.; Shang, J.; Sun, S.; Wang, H.; Wang, X.; Zhang, N.; Zhang, P.; Zhang, R.; Zhu, S.; Scherer, A.; Wang, J.; Wang, J.; Xu, J.; Hong, H.; Xiao, W.; Liang, X.; Jin, L.; The Quartet Project Team, ; Tong, W.; Ding, C.; Li, J.; Fang, X.; Shi, L.
10.1101/2022.10.24.513612 — systems biology — Posted on 2022-10-26
730 THE RELATIONSHIP BETWEEN TERROIR AND THE PHENOLOGY OF BAROSSA SHIRAZ
Bonada, M.; Victor, S. O.; Thomas, D.; Collins, C.; Schmidtke, L.; Phogat, V.; Petrie, P. R.
10.1101/2022.10.25.513684 — plant biology — Posted on 2022-10-26
733 The structure of pathogenic huntingtin exon-1 defines the bases of its aggregation propensity
Elena-Real, C. A.; Sagar, A.; Urbanek, A.; Popovic, M.; Morato, A.; Estana, A.; Fournet, A.; Lund, X. L.; Shi, Z.-D.; Costa, L.; Thureau, A.; Allemand, F.; Swenson, R. E.; Milhiet, P.-E.; Barducci, A.; Cortes, J.; Sinnaeve, D.; Sibille, N.; Bernado, P.
10.1101/2022.10.25.513661 — biophysics — Posted on 2022-10-26
734 SurvivalML: an integrative platform for the discovery and exploration of prognostic models in multi-center cancer cohorts
Liu, Z.; Xu, H.; Liu, L.; Weng, S.; Xing, Z.; Ren, Y.; Ge, X.; Wang, L.; Guo, C.; Chen, S.; Cheng, Q.; Luo, P.; Zhang, J.; Han, X.
10.1101/2022.10.25.513678 — bioinformatics — Posted on 2022-10-26
738 Antagonistic roles of canonical and alternative RPA in tandem CAG repeat diseases
Gall-Duncan, T.; Luo, J.; Jurkovic, C.-M.; Fischer, L.; Fujita, K.; Leib, D.; Li, V.; Harding, R. J.; Tran, S.; Chen, R.; Tanaka, H.; Deshmukh, A. L.; Mason, A. G.; Levesque, D.; Khan, M.; Lanni, S.; Sato, N.; Caron, M.-C.; Masson, J.-Y.; Panigrahi, G. B.; Prasolava, T.; Wang, P.; Lau, R.; Tippett, L.; Turner, C.; La Spada, A. R.; Campos, E. I.; Curtis, M. A.; Boisvert, F.-M.; Faull, R. L.; Davidson, B. L.; Okazawa, H.; Wold, M. S.; Pearson, C. E.
10.1101/2022.10.24.513561 — genetics — Posted on 2022-10-26
740 Hsp47 Promotes Biogenesis of Multi-subunit Neuroreceptors in the Endoplasmic Reticulum
Wang, Y.-J.; Di, X.-J.; Han, D.-Y.; Nashmi, R.; Henderson, B. J.; Moss, F. J.; Mu, T.-W.
10.1101/2022.10.24.513629 — cell biology — Posted on 2022-10-26
742 Quantitative super-resolution imaging of platelet degranulation reveals differential release of VWF and VWF propeptide from alpha-granules
Swinkels, M.; Hordijk, S.; Bürgisser, P. E.; Slotman, J. A.; Carter, T.; Leebeek, F. W. G.; Jansen, A. J. G.; Voorberg, J.; Bierings, R.
10.1101/2022.10.25.513669 — cell biology — Posted on 2022-10-26
743 A Taxonomy of Seizure Spread Patterns, Speed of Spread, and Associations With Structural Connectivity
Revell, A. Y.; Pattnaik, A. R.; Conrad, E.; Sinha, N.; Scheid, B. H.; Lucas, A.; Bernabei, J. M.; Beckerle, J.; Stein, J. M.; Das, S. R.; Litt, B.; Davis, K. A.
10.1101/2022.10.24.513577 — neuroscience — Posted on 2022-10-26
744 Metabolic robustness to growth temperature of cold adapted bacterium
Riccardi, C.; Calvanese, M.; Ghini, V.; Alonso-Vasquez, T.; Perrin, E.; Turano, P.; Giurato, G.; Weisz, A.; Parrilli, E.; Tutino, M. L.; Fondi, M.
10.1101/2022.10.25.513664 — systems biology — Posted on 2022-10-26
746 HSPB1 facilitates chemoresistance through inhibiting ferroptotic cancer cell death and regulating NF-κB signaling pathway in breast cancer
Liang, Y.; Wang, Y.; Zhang, Y.; Ye, F.; Luo, D.; Li, Y.; Jin, Y.; Han, D.; Wang, Z.; Chen, B.; Zhao, W.; Wang, L.; Chen, X.; Ma, T.; Kong, X.; Yang, Q.
10.1101/2022.10.25.513668 — cancer biology — Posted on 2022-10-26
748 Oncogenic context shapes the fitness landscape of tumor suppression
Blair, L. M.; Juan, J. M.; Sebastian, L.; Tran, V. B.; Nie, W.; Wall, G. D.; Gerceker, M.; Lai, I. K.; Apilado, E. A.; Grenot, G.; Amar, D.; Foggetti, G.; Do Carmo, M.; Ugur, Z.; Deng, D.; Chenchik, A.; Paz Zafra, M.; Dow, L. E.; Politi, K.; MacQuitty, J. J.; Petrov, D. A.; Winslow, M. M.; Rosen, M. J.; Winters, I. P.
10.1101/2022.10.24.511787 — cancer biology — Posted on 2022-10-26
750 The role of hydrodynamic flow in the self-assembly of dragline spider silk proteins
Herrera Rodriguez, A. M.; Dasanna, A. K.; Daday, C.; Cruz-Chu, E. R.; Aponte Santamaria, C.; Schwarz, U. S.; Graeter, F.
10.1101/2022.10.25.513683 — biophysics — Posted on 2022-10-26
753 Ultra-fast joint-genotyping with SparkGOR
Gudbjartsson, H.; Isleifsson, H. b.; Ragnarsson, B.; Guimaraes, R.; Wu, H.; Olafsdottir, H.; Stefasson, S. K.
10.1101/2022.10.25.513331 — bioinformatics — Posted on 2022-10-26
755 Development of Scaffold-free 3D Cholangiocyte Organoids to Study the Progression of Primary Sclerosing Cholangitis
Zhang, W.; Kyritsi, K.; Isidan, A.; Park, Y.; Li, P.; Cross-Najafi, A. A.; Lopez, K.; Kennedy, L.; Sato, K.; Glaser, S.; Francis, H.; Alpini, G.; Ekser, B.
10.1101/2022.10.24.513594 — bioengineering — Posted on 2022-10-26
756 Overproduction of Native and Click-able Colanic Acid Slime from Engineered Escherichia coli
Sadler, J. C.; Brewster, R. C.; Gonzalez, A. F.; Nirkko, J. S.; Varzandeh, S.; Wallace, S.
10.1101/2022.10.25.513687 — bioengineering — Posted on 2022-10-26
757 Echolocating bats prefer a high risk-high gain foraging strategy to increase prey profitability
Stidsholt, L.; Hubancheva, A.; Greif, S.; Goerlitz, H. R.; Johnson, M. P.; Yovel, Y.; Madsen, P. T.
10.1101/2022.10.25.513681 — animal behavior and cognition — Posted on 2022-10-26
758 Assembly of the 81.6 Mb centromere of pea chromosome 6 elucidates the structure and evolution of metapolycentric chromosomes
Macas, J.; Avila Robledillo, L.; Kreplak, J.; Novak, P.; Koblizkova, A.; Vrbova, I.; Burstin, J.; Neumann, P.
10.1101/2022.10.25.513671 — genomics — Posted on 2022-10-26
760 A SNP affects Wnt4 expression in endometrial stroma, with antagonistic implications for pregnancy, endometriosis and reproductive cancers
Pavlicev, M.; McDonough-Godlstein, C.; Moset Zupan, A.; Muglia, L.; Hu, Y.-C.; Kong, F.; Monangi, N.; Dagdas, G.; Zupancic, N.; Maziarz, J.; Sinner, D.; Wagner, G.; Muglia, L.
10.1101/2022.10.25.513653 — genetics — Posted on 2022-10-26
761 Spatially resolved human kidney multi-omics single cell atlas highlights the key role of the fibrotic microenvironment in kidney disease progression
Abedini, A.; Ma, Z.; Frederick, J.; Dhillon, P.; S. Balzer, M.; Shrestha, R.; Liu, H.; Vitale, S.; Devalaraja-Narashimha, K.; Grandi, P.; Bhattacharyya, T.; Hu, E.; S. Pullen, S.; M Boustany-Kari, C.; Guarnieri, P.; Karihaloo, A.; Yan, H.; Coleman, K.; Palmer, M.; Sarov-Blat, L.; Morton, L.; A. Hunter, C.; Li, M.; Susztak, K.
10.1101/2022.10.24.513598 — genetics — Posted on 2022-10-26
762 Design and performance of a long-read sequencing panel for pharmacogenomics
van der Lee, M.; Busscher, L.; Menafra, R.; Zhai, Q.; van den Berg, R. R.; Kingan, S. B.; Gonzaludo, N.; Hon, T.; Han, T.; Arbiza, L.; Numanagic, I.; Kloet, S. L.; Swen, J. J.
10.1101/2022.10.25.513646 — genetics — Posted on 2022-10-26
766 YAP condensates are highly organized hubs for YAP/TEAD transcription
Hao, S.; Fuehrer, H.; Flores, E.; Demmerle, J.; Lippincott-Schwartz, J.; Liu, Z.; Sukenik, S.; Cai, D.
10.1101/2022.10.24.513621 — cell biology — Posted on 2022-10-26
769 A SOD1-dependent mitotic DNA damage checkpoint
Gatenby, R. J.; Li, N.; Lata, P.; Walne, T.; Tufail, A.; Breitweiser, A.; Thompson, R. H.
10.1101/2022.10.26.513831 — molecular biology — Posted on 2022-10-26
772 Label-free adaptive optics single-molecule localization microscopy for whole animals
Park, S.; Jo, Y.; Kang, M.; Hong, J. H.; Ko, S.; Kim, S.; Park, S.; Park, H.-C.; Shim, S.-H.; Choi, W.
10.1101/2021.11.18.469175 — biophysics — Posted on 2022-10-26
776 SARS-CoV-2 S1 Subunit Booster Vaccination Elicits Robust Humoral Immune Responses in Aged Mice
Kim, E.; Khan, M. S.; Ferrari, A.; Huang, S.; Sammartino, J. C.; Percivalle, E.; Kenniston, T. W.; Cassaniti, I.; Baldanti, F.; Gambotto, A.
10.1101/2022.10.25.513090 — microbiology — Posted on 2022-10-26
777 Intratumor Childhood Vaccine-Specific CD4+ T cell Recall Coordinates Antitumor CD8+ T cells and Eosinophils
Brown, M. C.; McKay, Z. P.; Yang, Y.; Beasley, G. M.; Ashley, D. M.; Bigner, D. D.; Nair, S. K.; Gromeier, M.
10.1101/2022.03.14.484260 — immunology — Posted on 2022-10-26
778 A rose flavor compound activating the NRF2 pathway in dendritic cells ameliorates contact hypersensitivity in mice
Kodama, N.; Okada, H.; Hachisu, M.; Ando, M.; Ito, N.; Nagata, K.; Yasuda, Y.; Hiroki, I.; Yashiro, T.; Ichihara, G.; Yamamoto, M.; Nishiyama, C.
10.1101/2022.02.08.479651 — immunology — Posted on 2022-10-26
780 Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics
Tian, S.; Zhan, D.; Yu, Y.; Liu, M.; Wang, Y.; Song, L.; Qin, Z.; Li, X.; Liu, Y.; Li, Y.; Ji, S.; Li, Y.; Li, L.; Wang, S.; Massive Analysis and Quality Control Consortium, ; Zheng, Y.; He, F.; Qin, J.; Ding, C.
10.1101/2022.10.25.513670 — molecular biology — Posted on 2022-10-26
781 Temporal integration is a robust feature of perceptual decisions
Hyafil, A.; de la Rocha, J.; Pericas, C.; Katz, L. N.; Huk, A. C.; Pillow, J. W.
10.1101/2022.10.25.513647 — neuroscience — Posted on 2022-10-26
782 Auxin-independent effects of apical dominance induce temporal changes in phytohormones
Cao, D.; Barbier, F.; Dun, E. A.; Fichtner, F.; Dong, L.; Kerr, S. C.; Beveridge, C. A.
10.1101/2022.10.24.513542 — plant biology — Posted on 2022-10-26
784 Precise temporal control of neuroblast migration through combined regulation and feedback of a Wnt receptor
C. Korswagen, H.; Schild, E. S.; Gupta, S.; Dubois, C.; Fernandes Povoa, E. E.; Felix, M.-A.; Mugler, A.
10.1101/2022.10.25.513666 — developmental biology — Posted on 2022-10-26
785 Characterization of Three Variants of SARS-CoV-2 in vivo Shows Host-Dependent Pathogenicity in Hamsters
Toomer, G.; Burns, W.; Melendez, M.; Garcia, L.; Henry, G.; Biancofiori, A.; Geroge, A.; Duffy, C.; Chu, J.; Sides, M.; Munoz, M.; Garcia, K.; Nikolai-Yogerst, A.; Peng, X.; Westfall, L.; Baker, R. O.
10.1101/2022.10.24.513632 — microbiology — Posted on 2022-10-26
786 Serum Amyloid A proteins reduce bone mass during mycobacterial infections
Cordeiro Gomes, A.; Sousa, D. M.; Oliveira, T. C.; Fonseca, O.; Pinto, R.; Silverio, D. F.; Fernandes, A. I.; Moreira, A. C.; Silva, T.; Teles, M. J.; Pereira, L.; Saraiva, M.; Lamghari, M.; Gomes, M. S.
10.1101/2022.10.24.513637 — immunology — Posted on 2022-10-26
787 Expansion Spatial Transcriptomics
Fan, Y.; Andrusivova, Z.; Wu, Y.; Chai, C.; Larsson, L.; He, M.; Luo, L.; Lundeberg, J.; Wang, B.
10.1101/2022.10.25.513696 — genomics — Posted on 2022-10-26
788 Two opposing gene expression patterns within ATRX aberrant neuroblastoma
van Gerven, M. R.; Schild, L.; van Arkel, J.; Koopmans, B.; Broeils, L. A.; Meijs, L. A. M.; van Oosterhout, R.; van Noesel, M. M.; Koster, J.; van Hooff, S. R.; Molenaar, J. J.; van den Boogaard, M.
10.1101/2022.10.25.513663 — cancer biology — Posted on 2022-10-26
790 A Bayesian model for human directional localization of broadband and static sound sources
Barumerli, R.; Majdak, P.; Geronazzo, M.; Avanzini, F.; Meijer, D.; Baumgartner, R.
10.1101/2022.10.25.513770 — neuroscience — Posted on 2022-10-25
792 Social memory in female mice is rapidly modulated by 17β-estradiol through ERK and Akt modulation of synapse formation
Sheppard, P. A. S.; Chandramohan, D.; Lumsden, A.; Vellone, D.; Denley, M. C. S.; Srivastava, D. P.; Choleris, E.
10.1101/2022.10.25.512385 — neuroscience — Posted on 2022-10-25
794 Cell types in the mouse amygdala and their transcriptional response to fear conditioning
Hochgerner, H.; Tibi, M.; Netser, S.; Ophir, O.; Reinhardt, N.; Singh, S.; Lin, Z.; Wagner, S.; Zeisel, A.
10.1101/2022.10.25.513733 — neuroscience — Posted on 2022-10-25
795 Tackling the challenges of group network inference from intracranial EEG data
Pidnebesna, A.; Sanda, P.; Kalina, A.; Hammer, J.; Marusic, P.; Vlcek, K.; Hlinka, J.
10.1101/2022.10.25.513590 — neuroscience — Posted on 2022-10-25
796 iPSC Motor Neurons with Familial ALS Mutations Capture Gene Expression Changes in Postmortem Sporadic ALS Motor Neurons
Held, A.; Adler, M.; Marques, C.; Kavuturu, A. S.; Quadros, A. R. A. A.; Ndayambaje, I. S.; Lara, E.; Ward, M.; Lagier-Tourenne, C.; Wainger, B. J.
10.1101/2022.10.25.513780 — neuroscience — Posted on 2022-10-25
797 oskar acts with the transcription factor Creb to regulate long-term memory in crickets
Kulkarni, A.; Ewen-Campen, B. S.; Terao, K.; Matsumoto, Y.; Li, Y.; Watanabe, T.; Kao, J.; Parhad, S. S.; Ylla, G.; Mizunami, M.; Extavour, C. G.
10.1101/2022.10.24.513429 — animal behavior and cognition — Posted on 2022-10-25
798 Gap-free nuclear and mitochondrial genomes of Ustilaginoidea virens strain JS60-2, a fungal pathogen causing rice false smut
Wang, Y.; Yang, L.; Yang, Q.; Dong, J.; Wang, Y.; Duan, Y.; Yin, W.-X.; Zheng, L.; Sun, W.; Fan, J.; Luo, C.; Li, G.
10.1101/2022.10.25.513643 — genomics — Posted on 2022-10-25
799 A ZTF-7/RPS-2 complex mediates the cold-warm response in C. elegans
Xu, T.; Liao, S.; Zhu, C.; Jin, Q.; Xu, D.; Fu, C.; Chen, X.; Feng, X.; Guang, S.
10.1101/2022.10.24.513624 — genetics — Posted on 2022-10-25
802 Gut Mycobiome Dysbiosis Is Linked to Hypertriglyceridemia among Home Dwelling Elderly Danes
AHMAD, H. F.; Castro Mejia, J. L.; Krych, L.; Khakimov, B.; Kot, W.; Bechshoft, R. L.; Reitelseder, S.; Hojfeldt, G. W.; Engelsen, S. B.; Holm, L.; Faust, K.; Nielsen, D. S.
10.1101/2020.04.16.044693 — microbiology — Posted on 2022-10-25
805 A HUMANIZED FCRN TRANSGENIC MOUSE FOR PRECLINICAL PHARMACOKINETICS STUDIES
Conner, C. M.; van Fossan, D.; Read, K.; Cowley, D. O.; Alvarez, O.; Xu, S. X.-R.; Webb, D. R.; Jarnagin, K.
10.1101/2022.10.24.513622 — immunology — Posted on 2022-10-25
810 Lmx1a is a master regulator of the cortical hem.
Iskusnykh, I. Y.; Fattakhov, N.; Li, Y.; Bihannic, L.; Kirchner, M. K.; Steshina, E.; Northcott, P. A.; Chizhikov, V. V.
10.1101/2022.10.25.513532 — neuroscience — Posted on 2022-10-25
813 Sex-biasing influence of autism-associated Ube3a gene overdosage at connectomic, behavioral and transcriptomic levels
Montani, C.; Pagani, M.; De Guzman, E.; Balasco, L.; Alvino, F.; De Felice, A.; Galbusera, A.; Nickl-Jockstat, T.; Lau, P.; Borsotti, N.; Pasqualetti, M.; Mattioni, L.; Provenzano, G.; Bozzi, Y.; Lombardo, M.; Gozzi, A.
10.1101/2022.10.25.513747 — neuroscience — Posted on 2022-10-25
819 The N-terminal GTPase of Miro1 regulates oligomer formation
Eberhardt, E. L.; Mohamed, A. A.; Vos, S.; Cianfrocco, M. A.
10.1101/2022.10.25.513744 — biochemistry — Posted on 2022-10-25
821 Structure-based stabilization of SOSIP Env enhances recombinant ectodomain durability and yield
Wrapp, D.; Mu, Z.; Thakur, B.; Janowska, K.; Ajayi, O.; Barr, M.; Parks, R.; Hahn, B. H.; Acharya, P.; Saunders, K. O.; Haynes, B. F.
10.1101/2022.10.25.513757 — biochemistry — Posted on 2022-10-25
826 OzFAD: Ozone-enabled fatty acid discovery reveals unexpected diversity in the human lipidome
Menzel, J. P.; Young, R. S. E.; Benfield, A. H.; Scott, J. S.; Butler, L. M.; Henriques, S. T.; Poad, B. L. J.; Blanksby, S. J.
10.1101/2022.10.24.513604 — molecular biology — Posted on 2022-10-25
827 One for all - Human kidney Caki-1 cells are highly susceptible to infection with corona- and other respiratory viruses
Daniels, A.; Fletcher, S. L.; Kerr, H.; Kratzel, A.; Kriplani, N.; Craig, N.; Hastie, J. C.; Digard, P.; Davies, P.; Thiel, V.; Tait-Burkard, C.
10.1101/2022.10.25.513760 — microbiology — Posted on 2022-10-25
828 Mitoxantrone Targets Both Host and Bacteria to Overcome Vancomycin Resistance in Enterococcus faecalis
da Silva, R. A. G.; Wong, J. J.; Antypas, H.; Choo, P. Y.; Goh, K.; Jolly, S.; Liang, C.; Sing, L. T. K.; Veleba, M.; Hu, G.; Chen, J.; Kline, K. A.
10.1101/2022.10.24.513631 — microbiology — Posted on 2022-10-25
830 Staphylococcus aureus FtsZ and PBP4 bind to the conformationally dynamic N-terminal domain of GpsB
Sacco, M. D.; Hammond, L. R.; Noor, R. E.; Bhattacharya, D.; Madsen, J. J.; Zhang, X.; Butler, S. G.; Kemp, M. T.; Jaskolka-Brown, A. C.; Khan, S. J.; Gelis, I.; Eswara, P. J.; Chen, Y.
10.1101/2022.10.25.513704 — microbiology — Posted on 2022-10-25
832 A fungal lytic polysaccharide monooxygenase is required for cell wall integrity, thermotolerance, and virulence of the fungal human pathogen Cryptococcus neoformans
Probst, C.; Hallas-Moller, M.; Ipsen, J. O.; Brooks, J. T.; Andersen, K.; Haon, M.; Berrin, J.-G.; Martens, H. J.; Nichols, C. B.; Johansen, K. S.; Alspaugh, J. A.
10.1101/2022.10.25.513642 — microbiology — Posted on 2022-10-25
835 P2RX7 signaling drives the differentiation of Th1 cells through metabolic reprogramming for aerobic glycolysis
Salles, E. M.; Raeder, P. H. L.; Angeli, C.; Santiago, V. F.; de Souza, C. N.; Ramalho, T.; Camara, N. O. S.; Palmisano, G.; Alvarez, J. M.; D'Imperio-Lima, M. R.
10.1101/2022.10.24.513424 — immunology — Posted on 2022-10-25
836 Proximity-dependent labeling identifies dendritic cells that prime the antitumor CD4+ T cell response
Chudnovskiy, A.; Nakandakari-Higa, S.; Castro, T. B.; Cui, A.; Lin, C.-H.; Sade-Feldman, M.; Phillips, B. K.; Pae, J.; Mesin, L.; Bortolatto, J.; Schweitzer, L. D.; Pasqual, G.; Lu, L.-F.; Hacohen, N.; Victora, G. D.
10.1101/2022.10.25.513771 — immunology — Posted on 2022-10-25
837 DRAM1 promotes antibacterial autophagy and lysosomal delivery of Mycobacterium marinum in macrophages
Banducci-Karp, A.; Xie, J.; Engels, S. A. G.; Sarantaris, C.; Varela, M.; Meijer, A. H.; van der Vaart, M.
10.1101/2022.10.25.513660 — immunology — Posted on 2022-10-25
841 Activation of a Latent Epitope Causing Differential Binding of Anti-Neutrophil Cytoplasmic Antibodies to Proteinase 3
Casal Moura, M.; Thompson, G. E.; Nelson, D. A.; Fussner, L. A.; Hummel, A. M.; Jenne, D. E.; Emerling, D.; Volkmuth, W.; Fervenza, F. C.; Kallenberg, C. G. M.; Langford, C. A.; McCune, J. W.; Merkel, P. A.; Monach, P. A.; Seo, P.; Spiera, R. F.; St. Clair, E. W.; Ytterberg, S. R.; Stone, J. H.; Robinson, W. H.; Specks, U.
10.1101/549063 — immunology — Posted on 2022-10-25
842 A comparison of claw removal methods on the post-release survival and claw regeneration of stone crab (Menippe mercenaria)
Walus, A. M.; Schneider, E. V. C.; Parker, E.; Brittain, C.; McGaw, I. J.; Hayes, D.; Peters, A. K.; VanLeeuwen, T. E.
10.1101/2022.10.24.513277 — zoology — Posted on 2022-10-25
844 Microfluidics-free single-cell genomics with templated emulsification
Clark, I. C.; Fontanez, K. M.; Meltzer, R. H.; Xue, Y.; Hayford, C.; May-Zhang, A.; D'Amato, C.; Osman, A.; Zhang, J. Q.; Hettige, P.; Ishibashi, J. S. A.; Delley, C. L.; Weisgerber, D. W.; Replogle, J. M.; Jost, M.; Phong, K. T.; Kennedy, V. E.; Peretz, C. A. C.; Kim, E. A.; Song, S.; Karlon, W.; Weissman, J. S.; Smith, C. C.; Gartner, Z. J.; Abate, A.
10.1101/2022.06.10.495582 — genomics — Posted on 2022-10-25
846 hgtseq: a standard pipeline to study horizontal gene transfer
Carpanzano, S.; Santorsola, M.; nf-core community, ; Lescai, F.
10.1101/2022.10.24.513588 — bioinformatics — Posted on 2022-10-25
847 The Molecular Signatures Database Revisited: Extending Support for Mouse Data
Castanza, A. S.; Recla, J. M.; Eby, D.; Thorvaldsdottir, H.; Bult, C. J.; Mesirov, J. P.
10.1101/2022.10.24.513539 — bioinformatics — Posted on 2022-10-25
849 Granulin Loss of Function in Human Mature Brain Organoids Implicates Astrocytes in TDP-43 Pathology
de Majo, M.; Koontz, M.; Marsan, E.; Salinas, N.; Ramsey, A.; Kuo, Y.-M.; Seo, K.; Li, H.; Draeger, N. M.; Leng, K.; Kurnellas, M.; Miyaoka, Y.; Klim, J. R.; Kampmann, M.; Ward, M. E.; Huang, E. J.; Ullian, E. M.
10.1101/2022.10.24.513566 — neuroscience — Posted on 2022-10-25
850 Skeletal muscle nuclei in mice are not post-mitotic
Borowik, A. K.; Davidyan, A.; Peelor, F. F.; Voloviceva, E.; Stephen, S.; Bubak, M. P.; Mobley, C. B.; McCarthy, J. J.; Dupont-Versteegden, E. E.; Miller, B. F.
10.1101/2022.10.24.513426 — physiology — Posted on 2022-10-25
851 Development and application of genetic ancestry reconstruction methods to study diversity of patient-derived models in the NCI PDXNet Consortium
Sanderson, B. J.; Lott, P.; Chiu, K.; Quino, J. E.; Vang, A. P.; Lloyd, M. W.; Srivastava, A.; PDXNet Consortium, ; Chuang, J. H.; Carvajal-Carmona, L. G.
10.1101/2022.10.24.513591 — cancer biology — Posted on 2022-10-25
852 Cell Painting transfer increases screening hit rate
Ethan, C.; Maxime, C.; Claudio, A. F.; Francisca, F. V.; Franck, P.; Elaine, D. N.; Guillaume, B.; Auguste, G.
10.1101/2022.10.24.513564 — bioinformatics — Posted on 2022-10-25
859 Genomic diversity of SARS-CoV-2 can be accelerated by mutations in the nsp14 gene
Takada, K.; Ueda, M. T.; Shichinohe, S.; Kida, Y.; Ono, C.; Matsuura, Y.; Watanabe, T.; Nakagawa, S.
10.1101/2020.12.23.424231 — microbiology — Posted on 2022-10-25
861 Localized APP pathology in the hippocampus is sufficient to result in progressive disorganization of the timing of neuronal firing patterns
Viana da Silva, S.; Haberl, M. G.; Gaur, K.; Patel, R.; Narayan, G.; Ledakis, M.; Fu, M. L.; Koo, E. H.; Leutgeb, J. K.; Leutgeb, S.
10.1101/2022.10.24.513188 — neuroscience — Posted on 2022-10-25
862 Sex-specific effects of voluntary wheel running on behavior and the gut microbiota-immune-brain axis in mice
Williams, Z. A.; Szyszkowicz, J. K.; Osborne, N.; Allehyany, B.; Nadon, C.; Udechukwu, M. C.; Santos, A.; Audet, M.-C.
10.1101/2022.10.24.513258 — neuroscience — Posted on 2022-10-25
870 PRR14 organizes H3K9me3-modifed heterochromatin at the nuclear lamina
Kiseleva, A. A.; Cheng, Y.-C.; Smith, C. L.; Katz, R.; Poleshko, A.
10.1101/2022.05.17.492278 — cell biology — Posted on 2022-10-25
871 Immunogenicity of the BA.5 Bivalent mRNA Vaccine Boosters
Collier, A.-r.; Miller, J.; Hachmann, N.; McMahan, K.; Liu, J.; Bondzie, E.; Gallup, L.; Rowe, M.; Shonberg, E.; Thai, S.; Barrett, J.; Borducchi, E.; Bouffard, E.; Jacob-Dolan, C.; Mazurek, C.; Mutoni, A.; Powers, O.; Sciacca, M.; Surve, N.; VanWyk, H.; Wu, C.; Barouch, D.
10.1101/2022.10.24.513619 — immunology — Posted on 2022-10-25
874 Deep Learning Enabled Label-free Cell Force Computation in Deformable Fibrous Environments
Padhi, A.; Daw, A.; Sawhney, M.; Talukder, M. M.; Agashe, A.; Kale, S.; Karpatne, A.; Nain, A.
10.1101/2022.10.24.513423 — biophysics — Posted on 2022-10-25
878 Determination of insulin secretion from stem cell-derived islets with liquid chromatography-tandem mass spectrometry
Olsen, C.; Wang, C.; Abadour, S.; Lundanes, E.; Hansen, A. S.; Skottvoll, F. S.; Scholz, H.; Wilson, S. R.
10.1101/2022.10.24.512117 — bioengineering — Posted on 2022-10-25
879 Deep proteome profiling with reduced carry over using superficially porous microfabricated nanoLC columns
Stejskal, K.; Op de Beeck, J.; Matzinger, M.; Duernberger, G.; Boychenko, O.; Jacobs, P.; Mechtler, K.
10.1101/2021.11.28.470272 — biochemistry — Posted on 2022-10-25
880 Cortico-Striatal Beta-Oscillations as a Marker of Learned Reward Value
Koloski, M. F.; Hulyalkar, S.; Tang, T.; Wu, X.; Fakhraei, L.; Mishra, J.; Ramanathan, D. S.
10.1101/2022.10.24.513264 — animal behavior and cognition — Posted on 2022-10-25
881 Complete sequencing of a cynomolgus macaque major histocompatibility complex haplotype
Karl, J.; Prall, T. M.; Bussan, H. E.; Varghese, J. M.; Pal, A.; Wiseman, R. W.; O'Connor, D. H.
10.1101/2022.10.24.513544 — genomics — Posted on 2022-10-25
883 Integrative single-cell meta-analysis reveals disease-relevant vascular cell states and markers in human atherosclerosis
Mosquera, J. V.; Wong, D.; Auguste, G.; Turner, A. W.; Hodonsky, C. J.; Lino Cardenas, C. L.; Theofilatos, K.; Bos, M.; Kavousi, M.; Peyser, P.; Mayr, M.; Kovacic, J. C.; Bjorkegren, J. L. M.; Malhotra, R.; van der Laan, S. W.; Zang, C.; Sheffield, N.; Miller, C. L.
10.1101/2022.10.24.513520 — genomics — Posted on 2022-10-25
886 Complete functional analysis of type IV pilus components of a reemergent plant pathogen reveals neofunctionalization of paralog genes
Merfa, M. V.; Zhu, X.; Shantharaj, D.; Gomez, L. M.; Naranjo, E.; Potnis, N.; Cobine, P. A.; De La Fuente, L.
10.1101/2022.10.24.513447 — microbiology — Posted on 2022-10-25
887 Morpho-electric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex
Chartrand, T.; Dalley, R.; Close, J.; Goriounova, N. A.; Lee, B. R.; Mann, R.; Miller, J. A.; Molnar, G.; Mukora, A.; Alfiler, L.; Baker, K.; Bakken, T. E.; Berg, J.; Bertagnolli, D.; Braun, T.; Brouner, K.; Casper, T.; Csajbok, E. A.; Dee, N.; Egdorf, T.; Enstrom, R.; Galakhova, A. A.; Gary, A.; Gelfand, E.; Goldy, J.; Hadley, K.; Heistek, T. S.; Hill, D.; Jorstad, N.; Kim, L.; Kocsis, A. K.; Kruse, L.; Leon, G.; Long, B.; Mallory, M.; McGraw, M.; McMillen, D.; Melief, E. J.; Mihut, N.; Ng, L.; Nyhus, J.; Omstead, V.; Peterfi, Z.; Pom, A.; Potekhina, L.; Rajanbabu, R.; Rozsa, M.; Ruiz, A.; Sa
10.1101/2022.10.24.511199 — neuroscience — Posted on 2022-10-25
889 NDEx IQuery: a multi-method network gene set analysis leveraging the Network Data Exchange
Pillich, R. T.; Chen, J.; Churas, C.; Fong, D.; Gyori, B. M.; Ideker, T.; Karis, K.; Liu, S. N.; Ono, K.; Pico, A.; Pratt, D.
10.1101/2022.10.24.513552 — bioinformatics — Posted on 2022-10-25
893 Accurate de novo prediction of RNA 3D structure with transformer network
Feng, C.; Wang, W.; Han, R.; Wang, Z.; Ye, L.; Du, Z.; Wei, H.; Zhang, F.; Peng, Z.; Yang, J.
10.1101/2022.10.24.513506 — bioinformatics — Posted on 2022-10-25
897 Environmental gradients reveal stress hubs predating plant terrestrialization
Dadras, A.; Fuerst-Jansen, J. M.; Darienko, T.; Krone, D.; Scholz, P.; Rieseberg, T. P.; Irisarri, I.; Steinkamp, R.; Hansen, M.; Buschmann, H.; Valerius, O.; Braus, G. H.; Hoecker, U.; Mutwil, M.; Ischebeck, T.; de Vries, S.; Lorenz, M.; de Vries, J.
10.1101/2022.10.17.512551 — evolutionary biology — Posted on 2022-10-25
898 Fitness seascapes are necessary for realistic modeling of the evolutionary response to drug therapy
King, E. S.; Maltas, J. A.; Weaver, D. T.; Barker-Clarke, R.; Pelesko, J.; Dolson, E.; Scott, J. G.
10.1101/2022.06.10.495696 — evolutionary biology — Posted on 2022-10-25
899 Part-night exposure to artificial light at night has more detrimental effects on aphid colonies than fully lit nights
Heinen, R.; Sanchez-Mahecha, O.; Bezemer, T. M.; Dominoni, D. M.; Knappe, C.; Kollmann, J.; Kopatsch, A.; Pfeiffer, Z. A.; Schloter, M.; Sturm, S.; Schnitzler, J. P.; Vlot, A. C.; Weisser, W. W.
10.1101/2022.10.24.513514 — ecology — Posted on 2022-10-25
900 Temperature seasonality and nutrient enrichment drive intra-annual community turnover in global grasslands
Garbowski, M.; Boughton, E.; Ebling, A.; Fay, P.; Hautier, Y.; Holz, H.; Jentsch, A.; Jurburg, S. D.; Ladouceur, E.; Martina, J.; Ohlert, T.; Raynaud, X.; Roscher, C.; Sonnier, G.; Tognetti, P. M.; Yahdjian, L.; Wilfahrt, P.; Harpole, W. S.
10.1101/2022.10.24.513509 — ecology — Posted on 2022-10-25
901 Alternative culture systems for bovine oocyte in vitro maturation: liquid marbles and differentially shaped 96-well plates
Fernandez-Montoro, A.; Angel-Velez, D.; Benedetti, C.; Azari-Dolatabad, N.; Bogado Pascottini, O.; Chaitanya Pavani, K.; Van Soom, A.
10.1101/2022.10.24.513502 — developmental biology — Posted on 2022-10-25
904 Graves' disease-associated TSHR gene is demethylated and expressed in human regulatory T cells
Salumets, A.; Tserel, L.; Kasela, S.; Limbach, M.; Milani, L.; Peterson, H.; Kisand, K.; Peterson, P.
10.1101/2022.10.24.513489 — immunology — Posted on 2022-10-25
913 Regeneration of Starfish Radial Nerve Cord restores animal mobility and unveils a new coelomocyte population
Magalhaes, F.; Andrade, C.; Simoes, B.; Brigham, F.; Valente, R.; Martinez, P.; Rino, J.; Sugni, M.; Coelho, A. V.
10.1101/2022.10.24.513254 — zoology — Posted on 2022-10-25
914 Graphicacy across age, education, and culture: a new tool to assess intuitive graphics skills
Ciccione, L.; Sable-Meyer, M.; Boissin, E.; Josserand, M.; Potier-Watkins, C.; Caparos, S.; Dehaene, S.
10.1101/2022.10.24.513063 — scientific communication and education — Posted on 2022-10-25
915 Proteogenomic Characterization Reveals Therapeutic Opportunities Related to Mitochondrial Function in Melanoma
Gil, J.; Kim, Y.; Doma, V.; Cakır, U.; Kuras, M.; Betancourt, L.; Pla Parada, I.; Sanchez, A.; Sugihara, Y.; Appelqvist, R.; Oskolas, H.; Lee, B.; de Siqueira Guedes, J.; Monnerat, G.; Reis Alves Carneiro, G.; CS Nogueira, F.; B. Domont, G.; Malm, J.; Baldetorp, B.; Wieslander, E.; Balazs Nemeth, I.; Szasz, A. M.; Jeong Kwon, H.; Hong, R.; Pawłowski, K.; Rezeli, M.; Timar, J.; Fenyö, D.; Karpati, S.; Marko-Varga, G.
10.1101/2022.10.24.513481 — cancer biology — Posted on 2022-10-25
917 Fast-exchanging spirocyclic rhodamine probes for aptamer-based super-resolution RNA imaging
Englert, D.; Burger, E.-M.; Lackner, J.; Lampe, M.; Bühler, B.; Grün, F.; Schokolowski, J.; Nienhaus, G. U.; Jäschke, A.; Sunbul, M.
10.1101/2022.10.24.513449 — biophysics — Posted on 2022-10-25
918 Tau amyloid polymorphism is shaped by local structural propensities of its protein sequence
Louros, N.; Wilkinson, M.; Tsaka, G.; Ramakers, M.; Morelli, C.; Garcia, T.; Gallardo, R. U.; D'Haeyer, S.; Goossens, V.; Audenaert, D.; Thal, D. R.; Ranson, N. A.; Radford, S. E.; Rousseau, F.; Schymkowitz, J.
10.1101/2022.10.24.512987 — biophysics — Posted on 2022-10-25
919 COOBoostR: an extreme gradient boosting-based tool for robust tissue or cell-of-origin prediction of tumors
Yang, S.; Ha, K.; Song, W.; Fujita, M.; K?bler, K.; Polak, P.; de Alba Rivas, C. G.; Pessina, P.; de Aja, J. S.; Rowbotham, S.; Bhetariya, P.; Dost, A.; Moye, A. L.; Hiyama, E.; Nakagawa, H.; Kim, C. F.; Kim, H.-G.; Lee, H.
10.1101/2022.10.24.513446 — bioinformatics — Posted on 2022-10-25
921 scifAI: Explainable machine learning for profiling the immunological synapse and functional characterization of therapeutic antibodies
Shetab Boushehri, S.; Essig, K.; Chlis, N.-K.; Herter, S.; Bacac, M.; Theis, F. J.; Glasmacher, E.; Marr, C.; Schmich, F.
10.1101/2022.10.24.513494 — bioinformatics — Posted on 2022-10-25
924 SDRAP for annotating scrambled or rearranged genomes
Braun, J.; Neme, R.; Feng, Y.; Landweber, L. F.; Jonoska, N.
10.1101/2022.10.24.513505 — bioinformatics — Posted on 2022-10-25
925 Adversarial Attacks on Protein Language Models
Carbone, G.; Cuturello, F.; Bortolussi, L.; Cazzaniga, A.
10.1101/2022.10.24.513465 — bioinformatics — Posted on 2022-10-25
926 Adaptive trends of sequence compositional complexity over pandemic time in the SARS-CoV-2 coronavirus
Oliver, J. L.; Bernaola-Galvan, P.; Perfectti, F.; Gomez-Martin, C.; Castiglione, S.; Raia, P.; Verdu, M.; Moya, A.
10.1101/2021.11.06.467547 — genomics — Posted on 2022-10-25
929 Airborne environmental DNA captures terrestrial vertebrate diversity in nature
Lynggaard, C.; Froslev, T. G.; Johnson, M. S.; Olsen, M. T.; Bohmann, K.
10.1101/2022.10.24.512985 — ecology — Posted on 2022-10-25
933 Protection from liver cancer in a mouse model of Alagille syndrome follows dysregulated differentiation of thymocytes and hepatocytes
Masek, J.; Filipovic, I.; Hankeova, S.; He, J.; Van Hul, N. K.; Belicova, L.; Jirouskova, M.; Frontino, A. M.; Turetti, F.; Oliveira, D. V.; Cervenka, I.; Sarnova, L.; Verboven, E.; Brabec, T.; Bjorkstrom, N. K.; Gregor, M.; Dobes, J.; Andersson, E. R.
10.1101/2022.10.24.513578 — developmental biology — Posted on 2022-10-25
934 Signal Peptide Peptidase-Like 2b affects APP cleavage and exhibits a biphasic Aβ-mediated expression in Alzheimer's disease.
Maccioni, R.; Travisan, C.; Zerial, S.; Wagener, A.; Andrade-Talavera, Y.; Picciau, F.; Grassi, C.; Chen, G.; Lemoine, L.; Fisahn, A.; Jiang, R.; Fluhrer, R.; Mentrup, T.; Schröder, B.; Nilsson, P.; Tambaro, S.
10.1101/2022.10.24.513473 — neuroscience — Posted on 2022-10-25
936 Representation and quantification Of Module Activity from omics data with rROMA
Cornet, M.; Najm, M.; Albergante, L.; Zinovyev, A.; Sermet-Gaudelus, I.; Stoven, V.; Calzone, L.; MARTIGNETTI, L.
10.1101/2022.10.24.513448 — systems biology — Posted on 2022-10-25
938 Combining two Genetic Sexing Strains allows sorting of non-transgenic males for Aedes genetic control
Lutrat, C.; Burckbuchler, M.; Olmo, R. P.; Beugnon, R.; Fontaine, A.; Akbari, O. S.; Argiles-Herrero, R.; Baldet, T.; Bouyer, J.; Marois, E.
10.1101/2022.03.11.483912 — bioengineering — Posted on 2022-10-25
939 Phenotypic and transcriptomic analyses reveal major differences between apple and pear scab nonhost resistance
VERGNE, E.; CHEVREAU, E.; RAVON, E.; GAILLARD, S.; PELLETIER, S.; BAHUT, M.; PERCHEPIED, L.
10.1101/2021.06.01.446506 — genomics — Posted on 2022-10-25
941 Helicobacter pylori FlgV forms a flagellar motor ring structure required for optimal motility
Hoover, T. R.; Botting, J. M.; Tachiyama, S.; Gibson, K. H.; Liu, J.; Starai, V. J.
10.1101/2022.10.24.513468 — microbiology — Posted on 2022-10-25
942 Umbilical cord blood-derived cell therapy for perinatal brain injury: A systematic review & meta-analysis of preclinical studies - Part B.
Purcell, E.; Nguyen, T.; Smith, M.; Penny, T.; Paton, M.; Zhou, L.; Jenkin, G.; Miller, S.; McDonald, C.; Malhotra, A.
10.1101/2022.10.20.513105 — neuroscience — Posted on 2022-10-25
944 A Chromosome-length Assembly of the Black Petaltail (Tanypteryx hageni) Dragonfly
Tolman, E.; Beatty, C. D.; Bush, J.; Kohli, M.; Moreno, C. M.; Ware, J. L.; Weber, K. S.; Khan, R.; Maheshwari, C.; Weisz, D.; Dudchenko, O.; Aiden, E. L.; Frandsen, P. B.
10.1101/2022.10.18.512723 — genomics — Posted on 2022-10-25
945 Hierarchical differences in the encoding of sound and choice in the subcortical auditory system
Mackey, C. A.; Dylla, M.; Bohlen, P.; Grigsby, J.; Hrnicek, A.; Mayfield, J. M.; Ramachandran, R.
10.1101/2022.06.15.496306 — neuroscience — Posted on 2022-10-25
948 Elucidation of Global Trends in the Effects of VX-661 and VX-445 on the Expression of Clinical CFTR Variants
McKee, A. G.; McDonald, E. F.; Penn, W. D.; Kuntz, C. P.; Noguera, K.; Chamness, L. M.; Roushar, F. J.; Meiler, J.; Oliver, K. E.; Plate, L.; Schlebach, J. P.
10.1101/2022.10.14.512300 — biochemistry — Posted on 2022-10-25
949 Neglected no longer: Phylogenomic resolution of higher-level relationships in Solifugae
Kulkarni, S.; Steiner, H.; Garcia, E.; Iuri, H.; Jones, R.; Ballesteros, J.; Gainett, G.; Graham, M. R.; Harms, D.; Lyle, R.; Ojanguren-Affilastro, A. A.; Santibanez-Lopez, C. E.; Silva de Miranda, G.; Cushing, P. E.; Gavish-Regev, E.; Sharma, P. P.
10.1101/2022.10.22.513338 — evolutionary biology — Posted on 2022-10-25
952 Molecular Basis for Interferon-mediated Pathogen Restriction in Human Cells
Matta, S. K.; Kohio, H. P.; Chandra, P.; Brown, A.; Doench, J. G.; A. Philips, J.; Ding, S.; Sibley, L. D.
10.1101/2022.10.21.513197 — microbiology — Posted on 2022-10-25
955 Flexible selection of task-relevant features through population gating
Barbosa, J.; Proville, R.; Rodgers, C. C.; DeWeese, M. R.; Ostojic, S.; Boubenec, Y.
10.1101/2022.07.21.500962 — neuroscience — Posted on 2022-10-25
956 Super-resolution mass spectrometry enables rapid, accurate, and highly-multiplexed proteomics at the MS2-level
Kozhinov, A. N.; Johnson, A.; Nagornov, K. O.; Stadlmeier, M.; Martin, L.; Dayon, L.; Corthesy, J.; Wuhr, M.; Tsybin, Y. O.
10.1101/2022.07.29.501912 — systems biology — Posted on 2022-10-25
957 An automated feeding system for the African killifish reveals effects of dietary restriction on lifespan and allows scalable assessment of associative learning
McKay, A.; Costa, E. K.; Chen, J.; Hu, C.-K.; Chen, X.; Bedbrook, C. N.; Khondker, R. C.; Thielvoldt, M.; Singh, P. P.; Wyss-Coray, T.; Brunet, A.
10.1101/2021.03.30.437790 — physiology — Posted on 2022-10-25
958 The Children's Brain Tumor Network (CBTN) - Accelerating Research in Pediatric Central Nervous System Tumors through Collaboration and Open Science
Lilly, J. V.; Rokita, J. L.; Mason, J. L.; Patton, T.; Stefankiewiz, S.; Higgins, D.; Trooskin, G.; Larouci, C. A.; Arya, K.; Appert, E.; Heath, A. P.; Zhu, Y.; Brown, M. A.; Zhang, B.; Farrow, B. K.; Robins, S.; Morgan, A. M.; Nguyen, T. Q.; Frenkel, E.; Lehmann, K.; Drake, E.; Sullivan, C.; Plisiewicz, A.; Coleman, N.; Patterson, L.; Koptyra, M.; Helili, Z.; Van Kuren, N.; Young, N. M.; Kim, M. C.; Friedman, C.; Lubneuski, A.; Blackden, C.; Williams, M.; Baubet, V.; Tauhid, L.; Galanaugh, J.; Boucher, K.; Ijaz, H.; Cole, K. A.; Choudhari, N.; Santi, M.; Moulder, R. W.; Waller, J.; Rife, W.;
10.1101/2022.10.14.511975 — cancer biology — Posted on 2022-10-25
962 Integrating T-cell receptor and transcriptome for large-scale single-cell immune profiling analysis
Drost, F.; An, Y.; Dratva, L. M.; Lindeboom, R. G.; Haniffa, M.; Teichmann, S. A.; Theis, F.; Lotfollahi, M.; Schubert, B.
10.1101/2021.06.24.449733 — bioinformatics — Posted on 2022-10-25
963 Metadata preservation and stewardship for genomic data is possible, but must happen now
Crandall, E. D.; Toczydlowski, R. H.; Liggins, L.; Holmes, A. E.; Ghoojaei, M.; Gaither, M. R.; Wham, B. E.; Pritt, A. L.; Noble, C.; Anderson, T. J.; Barton, R. L.; Berg, J. T.; Beskid, S. G.; Delgado, A.; Farrell, E.; Himmelsbach, N.; Queeno, S. R.; Trinh, T.; Weyand, C. A.; Bentley, A.; Deck, J.; Riginos, C.; Bradburd, G. S.; Toonen, R. J.
10.1101/2022.09.12.507034 — bioinformatics — Posted on 2022-10-25
966 Haplotype-phased and chromosome-level assembly of Puccinia polysora, a giga-scale fungal pathogen causing southern corn rust
Liang, J.; Li, Y.; Dodds, P. N.; Figueroa, M.; Sperschneider, J.; Han, S.; Tsui, C. K. M.; Zhang, K.; Li, L.; Ma, Z.; Cai, L.
10.1101/2022.05.18.492400 — genomics — Posted on 2022-10-25
971 Raw milk kefir: microbiota, bioactive peptides, and immune modulation.
Baars, T.; van Esch, B.; van Ooijen, L.; Zhang, Z.; Dekker, P.; Boeren, S.; Diks, M.; Garssen, J.; Hettinga, K.; Kort, R.
10.1101/2022.10.19.512868 — microbiology — Posted on 2022-10-25
972 The Hair Cell Analysis Toolbox: A machine learning-based whole cochlea analysis pipeline
Buswinka, C. J.; Osgood, R. T.; Simikyan, R. G.; Rosenberg, D. B.; Indzhykulian, A. A.
10.1101/2021.10.12.464098 — neuroscience — Posted on 2022-10-25
976 A stochastic hybrid model for DNA replication incorporating protein mobility dynamics
Windhager, J.; Paine, A.; Nathanailidou, P.; Tasiudi, E.; Rodriguez Martinez, M.; Lygeros, J.; Lygerou, Z.; Rapsomaniki, M. A.
10.1101/583187 — systems biology — Posted on 2022-10-25
977 Effects of Milk Fat Globule Epidermal Growth Factor VIII On Age-Associated Arterial Elastolysis, Fibrosis, and Calcification
Kim, S. H.; Liu, L.; Ni, L.; Zhang, L.; Zhang, J.; Wang, Y.; McGraw, K. R.; Monticone, R. E.; Telljohann, R.; Morrell, C.; Lakatta, E. G.; Wang, M.
10.1101/2020.10.05.326728 — pathology — Posted on 2022-10-25
978 Improved KCNQ2 gene missense variant interpretation with artificial intelligence
Saez-Matia, A.; Muguruza-Montero, A.; M-Alicante, S.; Nunez, E.; Ramis, R.; Ballesteros, O. R.; Garcia-Ibarlueza, M.; Fons, C.; Leonardo, A.; Bergara, A.; Villarroel, A.
10.1101/2022.10.20.513007 — pathology — Posted on 2022-10-25
979 The identification of a gene expression signature of primordial follicle activation in mouse pregranulosa cells
Frost, E. R.; Taylor, G.; Boeing, S.; Galichet, C.; Baker, M. A.; Sutherland, J. M.; Lovell-Badge, R.
10.1101/2022.10.24.513438 — developmental biology — Posted on 2022-10-24
980 Comprehensive cell atlas of the first-trimester developing human brain
Braun, E.; Danan-Gotthold, M.; Borm, L. E.; Vinsland, E.; Lee, K. W.; Lönnerberg, P.; Hu, L.; Li, X.; He, X.; Andrusivova, Z.; Lundeberg, J.; Arenas, E.; Barker, R. A.; Sundström, E.; Linnarsson, S.
10.1101/2022.10.24.513487 — developmental biology — Posted on 2022-10-25
983 Spatiotemporal tissue maturation of thalamocortical pathways in the human fetal brain
Wilson, S.; Pietsch, M.; Cordero-Grande, L.; Christiaens, D.; Uus, A.; Karolis, V. R.; Kyriakopoulou, V.; Colford, K.; Price, A.; Hutter, J.; Rutherford, M.; Hughes, E.; Counsell, S.; Tournier, J.-D.; Hajnal, J. V.; Edwards, D.; O'Muicheartaigh, J.; Arichi, T.
10.1101/2022.10.24.513491 — neuroscience — Posted on 2022-10-25
984 Single-cell analysis of prenatal and postnatal human cortical development
Velmeshev, D.; Perez, Y.; Yan, Z.; Valencia, J. E.; Castaneda-Castellanos, D. R.; Schirmer, L.; Mayer, S.; Wick, B.; Wang, S.; Nowakowski, T. J.; Paredes, M.; Huang, E. J. J.; Kriegstein, A.
10.1101/2022.10.24.513555 — neuroscience — Posted on 2022-10-25
985 A cross-species proteomic map of synapse development reveals neoteny during human postsynaptic density maturation
Wang, L.; Pang, K.; Zhou, L.; Cebrian-Silla, A.; Gonzalez-Granero, S.; Wang, S.; Bi, Q.; White, M. L.; Ho, B.; Li, J.; Li, T.; Perez, Y.; Huang, E. J.; Winkler, E. A.; Paredes, M. F.; Kovner, R.; Sestan, N.; Pollen, A. A.; Liu, P.; Li, J.; Piao, X.; Garcia-Verdugo, J. M.; Alvarez-Buylla, A.; Liu, Z.; Kriegstein, A. R.
10.1101/2022.10.24.513541 — neuroscience — Posted on 2022-10-25
988 Survivin Regulates Intracellular Stiffness and Extracellular Matrix Production in Vascular Smooth Muscle Cells
Krajnik, A.; Nimmer, E.; Sullivan, A.; Joseph, B. A.; Heo, Y.; Krug, A.; Kolega, J.; Heo, S.-J.; Lee, K.; Weil, B. R.; Kim, D.-H.; Bae, Y.
10.1101/2022.10.24.513582 — cell biology — Posted on 2022-10-24
989 Deletion of the ion channel Trpm4 increases cardiac inflammatory markers and fibrosis after myocardial infarction in mice
Boukenna, M.; Rougier, J.-S.; Aghagolzadeh, P.; Pradervand, S.; Guichard, S.; Haemmerli, A.-F.; Pedrazzini, T.; Abriel, H.
10.1101/2022.10.24.513479 — molecular biology — Posted on 2022-10-24
990 Relative enrichment of oral bacteria in feces indicates loss of intestinal commensals with implications for host health
Liao, C.; Rolling, T.; Djukovic, A.; Liu, H.; Dai, L.; Zhai, B.; Peled, J. U.; van den Brink, M. R. M.; Hohl, T. M.; Xavier, J.
10.1101/2022.10.24.513595 — microbiology — Posted on 2022-10-24
992 Microbial diversity and community dynamics in an active, high CO2 subsurface rift ecosystem
Lipus, D.; Jia, Z.; Sondermann, M.; Bussert, R.; Bartholomaeus, A.; Yang, S.; Wagner, D.; Kallmeyer, J.
10.1101/2022.10.24.511890 — microbiology — Posted on 2022-10-24
993 A Compensatory RNase E Variation Increases Iron Piracy and Virulence in Multidrug-Resistant Pseudomonas aeruginosa during Macrophage Infection
Vaillancourt, M.; Galdino, A. C. M.; Limsuwannarot, S. P.; Celedonio, D.; Dimitrova, E.; Broerman, M.; Bresee, C.; Doi, Y.; Lee, J. S.; Parks, W. C.; Jorth, P.
10.1101/2022.10.24.513460 — microbiology — Posted on 2022-10-24
995 A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation
Altea-Manzano, P.; Doglioni, G.; Cuadros, A. M.; Nolan, E.; Fernandez-Garcia, J.; Wu, Q.; Cidre-Aranaz, F.; Montagne, A.; Planque, M.; Marin-Bejar, O.; Van Elsen, J.; Vermeire, I.; Broekaert, D.; Riera-Domingo, C.; Richard, F.; Geukens, T.; De Schepper, M.; Leduc, S.; Hatse, S.; Lambrechts, Y.; Kay, E.; Lilla, S.; Demeyer, S.; Geldhof, V.; Boeckx, B.; Alekseenko, A.; de la Calle Arregui, C.; Floris, G.; Marine, J.-C.; Lambrechts, D.; Pelechano, V.; Mazzone, M.; Zanivan, S.; Cools, J.; Wildiers, H.; Baud, V.; Gruenewald, T. G. P.; Desmedt, C.; Malanchi, I.; Fendt, S.-M.
10.1101/2022.10.24.513556 — cancer biology — Posted on 2022-10-24
997 A 3D CELL-FREE BONE MODEL SHOWS COLLAGEN MINERALIZATION IS A PHYSICOCHEMICAL PROCESS DRIVEN AND CONTROLLED BY THE MATRIX
Van der Meijden, R. H. M.; Daviran, D.; Rutten, L.; Walboomers, F.; Macias-Sanchez, E.; Sommerdijk, N.; Akiva, A.
10.1101/2022.10.24.513466 — biochemistry — Posted on 2022-10-24
998 Citrus genomic resources unravel putative genetic determinants of Huanglongbing, a pathogen-triggered immune disease
Gao, Y.; Xu, J.; Li, Z.; Zhang, Y.; Riera, N.; Xiong, Z.; Ouyang, Z.; Liu, X.; Lu, Z.; Seymour, D.; Zhong, B.; Wang, N.
10.1101/2022.10.24.513527 — genomics — Posted on 2022-10-24
999 E2 ubiquitin conjugase Bendless is essential for PINK1-Park activity to regulate Mitofusin under mitochondrial stress
Cheramangalam, R. N.; Anand, T.; Pandey, P.; Balasubramaniyan, D.; Varghese, R.; Singhal, N.; Jaiswal, S. N.; Jaiswal, M.
10.1101/2022.10.24.513457 — genetics — Posted on 2022-10-24
1000 Transposons repressed by H3K27me3 were co-opted as cis-regulatory elements of H3K27me3 controlled protein coding genes during evolution of plants
Hisanaga, T.; Wu, S.; Romani, F.; Kowar, T.; Linterman, R.; Jamge, B.; Montgomery, S. A.; Axelsson, E.; Dierschke, T.; Bowman, J.; Fujiwara, T.; Hirooka, S.; Miyagishima, S.-y.; Dolan, L.; Schubert, D.; Berger, F.
10.1101/2022.10.24.513474 — evolutionary biology — Posted on 2022-10-24
1003 Tuft cells mediate commensal remodeling of the small intestinal antimicrobial landscape
Fung, C.; Fraser, L. M.; Barron, G. M.; Gologorsky, M. B.; Atkinson, S. N.; Gerrick, E. R.; Hayward, M.; Ziegelbauer, J.; Li, J. A.; Nico, K. F.; Tyner, M. D. W.; DeSchepper, L. B.; Pan, A.; Salzman, N. H.; Howitt, M. R.
10.1101/2022.10.24.512770 — microbiology — Posted on 2022-10-24
1004 A quorum of mechano-sensing fungal consortia
Garcia-Navarrete, M.; Ruiz Sanchis, D.; Sanchez-Munoz, I.; Gonzalez-Ruiz, S.; Avdovic, M.; Atienza-Sans, S.; Wabnik, K.
10.1101/2022.10.24.513463 — microbiology — Posted on 2022-10-24
1005 Exposing New Taxonomic Variation with Inflammation-A Murine Model-Specific Genome Database for Gut Microbiome Researchers
Leleiwi, I.; Rodriguez-Ramos, J.; Shaffer, M.; Sabag-Daigle, A.; Kokkinias, K.; Flynn, R. M.; Daly, R. A.; Kop, L. F.; Solden, L. M.; Ahmer, B. M. M.; Borton, M. A.; Wrighton, K. C.
10.1101/2022.10.24.513540 — microbiology — Posted on 2022-10-24
1006 Glucuronoxylomannan intranasal challenge prior to Cryptococcus neoformans pulmonary infection enhances cerebral cryptococcosis in rodents
Lee, H. H.; Carmichael, D. J.; Ribeiro, V.; Parisi, D. N.; Munzen, M. E.; Hamed, M. F.; Kaur, E.; Mishra, A.; Patel, J.; Rooklin, R.; Sher, A.; Carrillo-Sepulveda, M. A.; Eugenin, E. A.; Dores, M. R.; Martinez, L. R.
10.1101/2022.10.24.513461 — microbiology — Posted on 2022-10-24
1010 Validation of antigen tetramers for the detection of antigen-specific B cells
Fitzpatrick, K. S.; Poljakov, K.; Bibby, M. G.; Remington, A. J.; Gray, M. D.; Boonyaratanakornkit, J.; Taylor, J. J.
10.1101/2022.10.24.513230 — immunology — Posted on 2022-10-24
1012 The nematode effector Mj-NEROSs interacts with ISP influencing plastid ROS production to suppress plant immunity
Stojilkovic, B.; Xiang, H.; Chen, Y.; Bauters, L.; Van de Put, H.; Steppe, K.; Liao, J.; de Almeida Engler, J.; Gheysen, G.
10.1101/2022.10.24.513376 — plant biology — Posted on 2022-10-24
1013 Peptides Mimicking RS Repeats Modulate Phase Separation of SRSF1, Revealing a Reliance on Combined Stacking and Electrostatic Interactions
Fargason, T. E.; De Silva, N. I. U.; King, E. M.; Zhang, Z.; Paul, T. M.; Shariq, J. A.; Zaharias, S. M.; Zhang, J.
10.1101/2022.10.24.511151 — biochemistry — Posted on 2022-10-24
1016 Complete functional analysis of type IV pilus components of a reemergent plant pathogen reveals neofunctionalization of paralog genes
Merfa, M. V.; Zhu, X.; Shantharaj, D.; Gomez, L. M.; Naranjo, E.; Potnis, N.; Cobine, P. A.; De La Fuente, L.
10.1101/2022.10.24.513447 — microbiology — Posted on 2022-10-24
1017 A neonatal mouse model characterizes transmissibility of SARS-CoV-2 variants and reveals a role for ORF8
Rodriguez-Rodriguez, B. A.; Ciabattoni, G.; Valero-Jimenez, A. M.; Crosse, K. M.; Schinlever, A.; Rodriguez-Galvan, J. J.; Duerr, R.; Yeung, S. T.; McGrath, M.; Loomis, C.; Khanna, K. M.; Desvignes, L.; Frieman, M.; Ortigoza, M. B.; Dittmann, M.
10.1101/2022.10.04.510658 — microbiology — Posted on 2022-10-24
1018 Blood and site of disease inflammatory profiles differ in HIV-1-infected pericardial tuberculosis patients
Mutavhatsindi, H.; Du Bruyn, E.; Ruzive, S.; Howlett, P.; Sher, A.; Mayer-Barber, K. D.; Barber, D. L.; Ntsekhe, M.; Wilkinson, R. J.; Riou, C.
10.1101/2022.10.21.513232 — immunology — Posted on 2022-10-24
1019 Targeting the pathological network: feasibility of network-based optimization of transcranial magnetic stimulation coil placement for treatment of psychiatric disorders
Cao, Z.; Xiang, X.; Zhao, Y.; Jiang, Y.; Xie, C.; Paillere-Martinot, M.-L.; Artiges, E.; Li, Z.; Daskalakis, Z. J.; Yang, Y.; Zhu, C.
10.1101/2022.10.23.513193 — neuroscience — Posted on 2022-10-24
1020 Physico-chemical characterization of single bacteria and spores using optical tweezers
Nilsson, D. P.; Jonsmoen, U. L.; Malyshev, D.; Oberg, R.; Wiklund, K.; Andersson, M.
10.1101/2022.10.24.513442 — biophysics — Posted on 2022-10-24
1022 Cytoplasmic folding, mis-folding, and early stages of aggregation
Samuel Russell, P. P.; Rickard, M. M.; Boob, M.; Gruebele, M.; Pogorelov, T. V.
10.1101/2022.10.23.513428 — biophysics — Posted on 2022-10-24
1027 UBAP2L-dependent coupling of PLK1 localization and stability during mitosis
Guerber, L.; Pangou, E.; Vuidel, A.; Liao, Y.; Kleiss, C.; Grandgirard, E.; Sumara, I.
10.1101/2022.10.24.513562 — cell biology — Posted on 2022-10-24
1028 Genomic epidemiology of Corynebacterium diphtheriae in New Caledonia
Tessier, E.; Hennart, M.; Badell-Ocando, E.; Passet, V.; Toubiana, J.; Biron, A.; Gourinat, A.-C.; Merlet, A.; Colot, J.; Brisse, S.
10.1101/2022.10.23.512725 — microbiology — Posted on 2022-10-24
1031 The regulatory landscape of the yeast phosphoproteome
Leutert, M.; Barente, A. S.; Fukuda, N. K.; Rodriguez-Mias, R. A.; Villen, J.
10.1101/2022.10.23.513432 — systems biology — Posted on 2022-10-24
1034 Century-long timelines of herbarium genomes predict plant stomatal response to climate change
Lang, P. L.; Erberich, J. M.; Lopez, L.; Weiss, C. L.; Amador, G.; Fung, H. F.; Latorre, S. M.; Lasky, J. R.; Burbano, H. A.; Exposito-Alonso, M.; Bergmann, D.
10.1101/2022.10.23.513440 — plant biology — Posted on 2022-10-24
1035 Early life low-calorie sweetener consumption impacts energy balance during adulthood
Hayes, A. M. R.; Tsan, L.; Kao, A. E.; Schwartz, G. M.; Tierno Lauer, L.; Klug, M. E.; Schier, L. A.; Kanoski, S. E.
10.1101/2022.10.23.513433 — physiology — Posted on 2022-10-24
1036 Lipid Droplets Fuel Small Extracellular Vesicle Biogenesis
Genard, G.; Tirinato, L.; Pagliari, F.; Da Silva, J.; Giammona, A.; Alquraish, F.; Bordas, M.; Marafioti, M. G.; Di Franco, S.; Jansen, J.; Garcia-Calderon, D.; Hanley, R.; Nistico, C.; Fukasawa, Y.; Mueller, T.; Krijgsveld, J.; Todaro, M.; Costanzo, F. S.; Stassi, G.; Nessling, M.; Richter, K.; Maass, K.; Liberale, C.; Seco, J.
10.1101/2022.10.24.513202 — cancer biology — Posted on 2022-10-24
1037 Extracellular ATP drives pancreatic cancer cell invasion via purinergic receptor-integrin interactions
Tomas Bort, E.; Joseph, M.; Wang, Q.; Carter, E.; Roth, N.; Gibson, J.; Samadi, A.; Kocher, H.; Simoncelli, S.; McCormick, P. J.; Grose, R. P.
10.1101/2022.10.24.513477 — cancer biology — Posted on 2022-10-24
1040 MdrDB: Mutation-induced drug resistance DataBase
Yang, Z.; Ye, Z.; Qiu, J.; Feng, R.; Li, D.; Hsieh, C.; Allcock, J.; Zhang, S.
10.1101/2022.10.20.513118 — bioinformatics — Posted on 2022-10-24
1041 Development of a clot-adhesive coating to improve the performance of thrombectomy devices
Skarbek, C.; Anagnostakou, V.; Procopio, E.; Epshtein, M.; Raskett, C.; Romagnoli, R.; Iviglia, G.; Morra, M.; Antonucci, M.; Nicoletti, A.; Caligiuri, G.; Gounis, M.
10.1101/2022.10.18.512663 — bioengineering — Posted on 2022-10-24
1042 Species-wide genomics of kakapo provides transformational tools to accelerate recovery
Guhlin, J. G.; Le Lec, M. F.; Wold, J.; Koot, E.; Winter, D.; Biggs, P.; Galla, S. J.; Urban, L.; Foster, Y.; Cox, M. P.; Digby, A.; Uddstrom, L.; Eason, D.; Vercoe, D.; Davis, T.; Kakapo Recovery Team, ; Howard, J. T.; Jarvis, E. J.; Robertson, F. E.; Robertson, B. C.; Gemmell, N.; Steeves, T. E.; Santure, A. W.; Dearden, P.
10.1101/2022.10.22.513130 — genomics — Posted on 2022-10-24
1043 A quarter-million-year-old polymorphism drives reproductive mode variation in the pea aphid
Rimbault, M.; Legeai, F.; Peccoud, J.; Mieuzet, L.; Call, E.; Nouhaud, P.; Defendini, H.; Maheo, F.; Marande, W.; Theron, N.; Tagu, D.; Le Trionnaire, G.; Simon, J.-C.; Jaquiery, J.
10.1101/2022.10.24.513443 — evolutionary biology — Posted on 2022-10-24
1046 Identifying fungal leaf spots on oilseed rape: could pictures help?
Bousset, L.; Ermel, M.; Bamme, B.; Penaud, A.; Carpezat, J.; Balesdent, M.-H.; Laval, V.; Palerme, M.; Parisey, N.
10.1101/2022.10.21.513129 — ecology — Posted on 2022-10-24
1048 SORORIN is an evolutionary conserved antagonist of WAPL
Prusen Mota, I.; Galova, M.; Schleiffer, A.; Nguyentan, T.-t.; Kovacikova, I.; Nishiyama, T.; Gregan, J.; Peters, J.-M.; Schlogelhofer, P.
10.1101/2022.10.24.513534 — cell biology — Posted on 2022-10-24
1051 Computationally restoring the potency of a clinical antibody against SARS-CoV-2 Omicron subvariants
Desautels, T. A.; Arrildt, K. T.; Zemla, A. T.; Lau, E. Y.; Zhu, F.; Ricci, D.; Cronin, S.; Zost, S.; Binshtein, E.; Scheaffer, S. M.; Engdahl, T. B.; Chen, E.; Goforth, J. W.; Vashchenko, D.; Nguyen, S.; Weilhammer, D. R.; Lo, J. K.-Y.; Rubinfeld, B.; Saada, E. A.; Weisenberger, T.; Lee, T.-H.; Whitener, B.; Case, J. B.; Ladd, A.; Silva, M. S.; Haluska, R. M.; Grzesiak, E. A.; Bates, T. W.; Petersen, B. K.; Thackray, L. B.; Segelke, B. W.; Lillo, A. M.; Sundaram, S.; Diamond, M. S.; Crowe, J. E.; Carnahan, R. H.; Faissol, D. M.
10.1101/2022.10.21.513237 — microbiology — Posted on 2022-10-24
1053 Nanoscale dynamics of streptococcal adhesion to AGE-modified collagen
Leiva-Sabadini, C.; Tiozzo-Lyon, P.; Hidalgo-Galleguillos, L.; Rivas, L.; Robles, A.; Fierro, A.; Barrera, N. P.; Bozec, L.; Schuh, C. M. A. P.; Aguayo, S.
10.1101/2022.10.23.513419 — microbiology — Posted on 2022-10-24
1055 Multi-omics of Circular RNAs and Their Responses to Hormones in Moso Bamboo (Phyllostachys edulis)
Wang, Y.; Wang, H.; Wang, H.; Zhou, R.; Wu, J.; Zhang, Z.; Jin, Y.; Li, T.; Kohnen, M.; Liu, X.; Wei, W.; Chen, K.; Gao, Y.; Ding, J.; Liu, B.; Zhang, H.; lin, c.; Gu, L.
10.1101/2022.10.23.513435 — plant biology — Posted on 2022-10-24
1056 Single-fibre proteomics reveals a greater fibre-type specific mitochondrial remodelling with moderate than high-intensity training.
Reisman, E.; Botella Ruiz, J.; Huang, C.; Schittenhelm, R. B.; Stroud, D. A.; Granata, C.; Chandrasiri, S.; Ramm, G.; Oorschot, V.; Caruana, N. J.; Bishop, D. J.
10.1101/2022.10.23.512956 — physiology — Posted on 2022-10-24
1059 Phenotypic alteration of low-density granulocytes in people with pulmonary post-acute sequalae of SARS-CoV-2 infection
Dean, L. S.; Devendra, G.; Jiyarom, B.; Subia, N.; Tallquist, M. V.; Nerurkar, V. R.; Chang, S. P.; Chow, D. C.; Shikuma, C. M.; Park, J.
10.1101/2022.10.22.513351 — immunology — Posted on 2022-10-24
1060 Antibody avidity and multi-specificity combined to confer protection against SARS-CoV-2 and resilience against viral escape
Burn Aschner, C.; Muthuraman, K.; Kucharska, I.; Cui, H.; Prieto, K.; Nair, M. S.; Wang, M.; Huang, Y.; Christie-Holmes, N.; Poon, B.; Lam, J.; Sultana, A.; Kozak, R.; Mubareka, S.; Rubinstein, J. L.; Rujas, E.; Treanor, B.; Ho, D. D.; Jetha, A.; Julien, J.-P.
10.1101/2022.10.23.513379 — immunology — Posted on 2022-10-24
1061 Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response
Patel, A.; Kumar, S.; Lai, L.; Chakravarthy, C.; Valanparambil, R.; Reddy, E. S.; Gottimukkala, K.; Bajpai, P.; Raju, D. R.; Edara, V. V.; Davis-Gardner, M. E.; Linderman, S.; Dixit, K.; Sharma, P.; Mantus, G.; Cheedarla, N.; Verkerke, H. P.; Frank, F.; Neish, A. S.; Roback, J. D.; Davis, C. W.; Wrammert, J.; Ahmed, R.; Suthar, M.; Sharma, A.; Murali-Krishna, K.; Chandele, A.; Ortlund, E. A.
10.1101/2022.10.24.513517 — immunology — Posted on 2022-10-24
1064 Antibody responses to Omicron BA.4/BA.5 bivalent mRNA vaccine booster shot
Wang, Q.; Bowen, A.; Valdez, R.; Gherasim, C.; Gordon, A.; Lihong, L.; Ho, D. D.
10.1101/2022.10.22.513349 — microbiology — Posted on 2022-10-24
1065 Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques
Hoang, T. N.; Viox, E. G.; Upadhyay, A. A.; Strongin, Z.; Tharp, G. K.; Pino, M.; Nchioua, R.; Hirschenberger, M.; Gagne, M.; Nguyen, K.; Harper, J. L.; Marciano, S.; Boddapati, A. K.; Pellegrini, K. L.; Tisoncik-Go, J.; Whitmore, L. S.; Karunakaran, K. A.; Roy, M.; Kirejczyk, S.; Curran, E. H.; Wallace, C.; Wood, J. S.; Connor-Stroud, F.; Kasturi, S. P.; Levit, R. D.; Gale, M.; Vanderford, T. H.; Silvestri, G.; Busman-Sahay, K.; Estes, J. D.; Vaccari, M.; Douek, D. C.; Sparrer, K. M. J.; Kirchhoff, F.; Johnson, R. P.; Schreiber, G.; Bosinger, S. E.; Paiardini, M.
10.1101/2022.10.21.512606 — immunology — Posted on 2022-10-24
1066 Engineering a Universal Dengue Virus Vaccine using a Virus-Like Particle Scaffold
Basore, D. A.; Barcellona, C. M.; Jordan, T. B.; Crone, D. E.; Isern, S.; Michael, S. F.; Bystroff, C.
10.1101/2022.10.11.511616 — molecular biology — Posted on 2022-10-24
1067 Genomic Variation, Population Structure, and Gene Flow across Asian Pikas
Dahal, N.; Romine, M. G.; Khatiwada, S.; Ramakrishnan, U.; Lamichhaney, S.
10.1101/2022.10.22.513340 — evolutionary biology — Posted on 2022-10-24
1071 Time or distance: predictive coding of Hippocampal cells
Abramson, S.; Kraus, B. J.; White, J. A.; Hasselmo, M. E.; Morris, G.; Derdikman, D.
10.1101/2022.10.23.513401 — neuroscience — Posted on 2022-10-24
1073 Improving fine-mapping by modeling infinitesimal effects
Cui, R.; Elzur, R. A.; Kanai, M.; Ulirsch, J. C.; Weissbrod, O.; Daly, M.; Neale, B.; Fan, Z.; Finucane, H. K.
10.1101/2022.10.21.513123 — bioinformatics — Posted on 2022-10-24
1074 MAVISp: Multi-layered Assessment of VarIants by Structure for proteins
Arnaudi, M.; Beltrame, L.; Degn, K.; Utichi, M.; Scrima, S.; Sackett, P. W.; Lambrughi, M.; Tiberti, M.; Papaleo, E.
10.1101/2022.10.22.513328 — bioinformatics — Posted on 2022-10-24
1075 Structural basis for the Rad6 activation by the Bre1 N-terminal domain
Shi, M.; Zhao, J.; Li, M.; Huang, W.; Bai, X.; Zhang, W.; Zhang, K.; Chen, X.; Xiang, S.
10.1101/2022.10.23.513400 — biochemistry — Posted on 2022-10-24
1076 BEST: a web application for comprehensive biomarker exploration on large-scale data in solid tumors
Liu, Z.; Liu, L.; Weng, S.; Xu, H.; Xing, Z.; Ren, Y.; Ge, X.; Wang, L.; Guo, C.; Li, L.; Cheng, Q.; Luo, P.; Zhang, J.; Han, X.
10.1101/2022.10.21.513300 — genomics — Posted on 2022-10-24
1077 A genome wide association study identifies a new variant associated with word reading fluency in Chinese children
Wang, Z.; Zhao, S.; Zhang, L.; Yang, Q.; Cheng, C.; Ding, N.; Zhu, Z.; Shu, H.; Liu, C.; Zhao, J.
10.1101/2022.10.23.513381 — genetics — Posted on 2022-10-24
1080 Uncovering transcriptional regulatory network during regeneration for boosting wheat transformation
Liu, X.; Bie, X.; Lin, X.; Li, M.; Wang, H.; Zhang, X.; Yang, Y.; Zhang, C.; Zhang, X.; Xiao, J.
10.1101/2022.10.21.513305 — developmental biology — Posted on 2022-10-24
1083 Hypothalamic melanin-concentrating hormone neurons integrate food-motivated appetitive and consummatory processes
Subramanian, K. S.; Lauer, L. T.; Hayes, A. M. R.; Decarie-Spain, L.; McBurnett, K.; Donohue, K. N.; Kao, A. E.; Bashaw, A. G.; Burdakov, D.; Noble, E. E.; Schier, L. A.; Kanoski, S. E.
10.1101/2022.10.23.513421 — neuroscience — Posted on 2022-10-24
1084 The autism spectrum disorder risk gene NEXMIF alters hippocampal CA1 cellular and network dynamics
Mount, R. A.; Athif, M.; O'Connor, M.; Saligrama, A.; Tseng, H.-a.; Sridhar, S.; Zhou, C.; Man, H.; Han, X.
10.1101/2022.10.21.513282 — neuroscience — Posted on 2022-10-24
1086 The matrisome of the murine and human dorsal root ganglion: a transcriptomal approach
Vroman, R.; Hunter, R.; Wood, M. J.; Davis, O. C.; Malfait, Z.; George, D. S.; Ren, D.; Tavares-Ferreira, D.; Price, T. J.; Malfait, A.-M.; Malfait, F.; Miller, R. E.; Syx, D.
10.1101/2022.10.22.513341 — neuroscience — Posted on 2022-10-24
1094 The trans-regulatory landscape of gene networks in plants
Hummel, N. F. C.; Zhou, A.; Li, B.; Markel, K.; Ornelas, I. J.; Shih, P. M.
10.1101/2022.10.23.513368 — plant biology — Posted on 2022-10-24
1098 SUsPECT: A pipeline for variant effect prediction based on custom long-read transcriptomes for improved clinical variant annotation
Salz, R.; Saraiva-Agostinho, N.; Vorsteveld, E.; van der Made, C. I.; Kersten, S.; Stemerdink, M.; Allen, J.; Volders, P.-J.; Hunt, S. E.; Hoischen, A.; 't Hoen, P. A. C.
10.1101/2022.10.23.513417 — bioinformatics — Posted on 2022-10-24
1101 Unsupervised Discovery of Ancestry Informative Markers and Genetic Admixture Proportions in Biobank-Scale Data Sets
Ko, S.; Chu, B. B.; Peterson, D.; Okenwa, C.; Papp, J. C.; Alexander, D. H.; Sobel, E. M.; Zhou, H.; Lange, K. L.
10.1101/2022.10.22.513294 — bioinformatics — Posted on 2022-10-24
1102 Microsecond pulse electrical stimulation modulates cell migration
Xiang, X.-W.; Liu, H.-T.; Liu, W.; Yan, Z.-Y.; Zeng, Y.-L.; Wang, Y.-J.; Liu, J.; Chen, Y.-C.; Yu, S.-X.; Zhu, C.-H.; Tao, X.-N.; Wang, C.; Wu, J.-T.; Du, Y.; Xu, X.-X.; Gao, H.; Jiu, Y.; Ma, J.; Qiu, J.; Chang, L.; Jing, G.; Liu, K.-F.; Liu, Y.-J.
10.1101/2022.10.23.513372 — bioengineering — Posted on 2022-10-24
1103 Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity
Marra, P. S.; Yamanashi, T.; Crutchley, K. J.; Wahba, N. E.; Anderson, Z.-E. M.; Modukuri, M.; Chang, G.; Tran, T.; Iwata, M.; Cho, H. R.; Shinozaki, G.
10.1101/2022.10.22.513357 — genetics — Posted on 2022-10-24
1104 The Genomic Diversity of the Eliurus genus in northern Madagascar with a Putative New Species
Sgarlata, G. M.; Rasolondraibe, E.; Salmona, J.; Le Pors, B.; Ralantoharijaona, T.; Rakotonanahary, A.; Jan, F.; Manzi, S.; Iribar-Pelozuelo, A.; Zaonarivelo, J. R.; Andriaholinirina, N. V.; Rasoloharijaona, S.; Chikhi, L.
10.1101/2022.10.21.513246 — evolutionary biology — Posted on 2022-10-24
1106 Neglected no longer: Phylogenomic resolution of higher-level relationships in Solifugae
Kulkarni, S.; Steiner, H.; Garcia, E.; Iuri, H.; Jones, R.; Ballesteros, J.; Gainett, G.; Graham, M. R.; Harms, D.; Lyle, R.; Ojanguren-Affilastro, A. A.; Santibanez-Lopez, C. E.; Silva de Miranda, G.; Cushing, P. E.; Gavish-Regev, E.; Sharma, P. P.
10.1101/2022.10.22.513338 — evolutionary biology — Posted on 2022-10-24
1108 Fish-microbe systems in the hostile but highly biodiverse Amazonian blackwaters
Sylvain, F.-E.; Leroux, N.; Normandeau, E.; Custodio, J.; Mercier, P.-L.; Bouslama, S.; Holland, A.; Barroso, D.; Luis Val, A.; Derome, N. J. A.
10.1101/2022.10.22.513327 — ecology — Posted on 2022-10-24
1114 Cytosolic pH controls fungal MAPK signaling and pathogenicity
Fernandes, T. R.; Mariscal Gomez, M.; Serrano, A.; Segorbe, D.; Fernandez-Acero, T.; Martin, H.; Turra, D.; Di Pietro, A.
10.1101/2022.10.23.513408 — microbiology — Posted on 2022-10-24
1119 High Angular Resolution Susceptibility Imaging and Estimation of Fiber Orientation Distribution Functions in Primate Brain
Gkotsoulias, D. G.; Mueller, R.; Jaeger, C.; Schlumm, T.; Mildner, T.; Eichner, C.; Pampel, A.; Jaffe, J.; Graessle, T.; Alsleben, N.; Chen, J.; Crockford, C.; Wittig, R.; Liu, C.; Moeller, H. E.
10.1101/2022.10.23.513390 — neuroscience — Posted on 2022-10-24
1122 Brain signatures of chronic gut inflammation
Hall, C. V.; Radford-Smith, G.; Savage, E.; Robinson, C.; Cocchi, L.; Moran, R. J.
10.1101/2022.10.22.513335 — neuroscience — Posted on 2022-10-24
1125 Meta-analysis of preclinical pharmacogenomic studies to discover robust and translatable biomarkers of drug response
Smirnov, P.; Nair, S. K.; Abbas-Aghababazadeh, F.; Feizi, N.; Smith, I.; Pugh, T. J.; Haibe-Kains, B.
10.1101/2022.10.22.513279 — cancer biology — Posted on 2022-10-24
1126 Targeting oncogenic Wnt/β-catenin signaling in adrenocortical carcinoma disrupts ECM expression and impairs tumor growth.
Penny, M. K.; Lerario, A. M.; Basham, K. J.; Chukkapalli, S.; Yu, Y.; Mohan, D. R.; LaPensee, C.; Converso-Baran, K.; Hoenerhoff, M.; Suarez Fernandez, L.; Gonzalez del Rey, C.; Giordano, T. J.; Han, R.; Newman, E. A.; Hammer, G. D.
10.1101/2022.10.23.509323 — cancer biology — Posted on 2022-10-24
1127 Conserved degronome features governing quality control-associated proteolysis
Mashahreh, B.; Armony, S.; Johansson, K. E.; Chappleboim, A.; Friedman, N.; Gardner, R.; Hartmann-Petersen, R.; Lindorff-Larsen, K.; Ravid, T.
10.1101/2022.04.06.487275 — cell biology — Posted on 2022-10-24
1128 PplT domain proteins - ubiquitous potential prokaryotic phospholipid translocases
Hauser, J. N.; Kengmo Tchoupa, A.; Zabel, S.; Nieselt, K.; Ernst, C. M.; Slavetinsky, C. J.; Peschel, A.
10.1101/2022.03.11.483950 — microbiology — Posted on 2022-10-24
1129 Disinhibition of the orbitofrontal cortex biases decision making in obesity
Seabrook, L. T.; Naef, L.; Baimel, C.; Judge, A. K.; Kenney, T.; Ellis, M.; Tayyab, T.; Armstrong, M.; Qiao, M.; Floresco, S. B.; Borgland, S. L.
10.1101/2020.04.02.022681 — neuroscience — Posted on 2022-10-24
1132 DANCE: A Deep Learning Library and Benchmark for Single-Cell Analysis
Ding, J.; Wen, H.; Tang, W.; Liu, R.; Li, Z.; Venegas, J.; Su, R.; Molho, D.; Jin, W.; Zuo, W.; Wang, Y.; Yang, R.; Xie, Y.; Tang, J.
10.1101/2022.10.19.512741 — bioinformatics — Posted on 2022-10-24
1133 Retrotransposon instability dominates the acquired mutation landscape of mouse induced pluripotent stem cells
Gerdes, P.; Lim, S. M.; Ewing, A. D.; Larcombe, M. R.; Chan, D.; Sanchez-Luque, F. J.; Walkner, L.; Carleton, A. L.; James, C.; Knaupp, A. S.; Carreira, P. E.; Nefzger, C. M.; Lister, R.; Richardson, S. R.; Polo, J. M.; Faulkner, G. J.
10.1101/2022.02.16.480772 — genomics — Posted on 2022-10-24
1135 Systematic loss of function screens identify pathway specific functional circular RNAs
Liu, L.; Neve, M.; Perlaza-Jimenez, L.; Hawdon, A.; Conn, S. J.; Zenker, J.; Tamayo, P.; Goodall, G. J.; Rosenbluh, J.
10.1101/2022.10.22.513321 — genetics — Posted on 2022-10-24
1136 Population level genetic memory of prior metabolic adaptation in E. coli
Katz, S.; Grajeda-Iglesias, C.; Agranovic, B.; Ghrayeb, A.; Abramovich, I.; Hilau, S.; Gottlieb, E.; Hershberg, R.
10.1101/2022.09.20.508651 — evolutionary biology — Posted on 2022-10-24
1139 Confounding effects of heart rate, breathing rate, and frontal fNIRS on interoception
Candia-Rivera, D.; Sappia, M. S.; Horschig, J. M.; Colier, W. N. J. M.; Valenza, G.
10.1101/2022.06.02.494474 — neuroscience — Posted on 2022-10-24
1144 Multiomic single-cell lineage tracing to dissect fate-specific gene regulatory programs
Jindal, K.; Adil, M. T.; Yamaguchi, N.; Wang, H. C.; Yang, X.; Kamimoto, K.; Rivera-Gonzalez, G. C.; Morris, S. A.
10.1101/2022.10.23.512790 — genomics — Posted on 2022-10-24
1145 Dysregulated H19/Igf2 expression disrupts cardiac-placental axis during development of Silver Russell Syndrome-like mouse models
Chang, S.; Fulmer, D.; Hur, S. K.; Thorvaldsen, J. L.; Li, L.; Lan, Y.; Rhon-Calderon, E.; Chen, X.; Epstein, J. A.; Bartolomei, M. S.
10.1101/2022.03.28.486058 — developmental biology — Posted on 2022-10-24
1146 OPS-γδ: allogeneic opsonin-secreting γδT cell immunotherapy for solid tumours mediates direct and bystander immunity
Fowler, D.; Barisa, M.; Southern Navarrete, A.; Nattress, C.; Hawkins, E.; Vassalou, E.; Kanouta, A.; Counsell, J.; Rota, E. M.; Vlckova, P.; Draper, B.; Tape, C. J.; Chester, K.; Anderson, J.; Fisher, J.
10.1101/2022.10.23.513387 — immunology — Posted on 2022-10-23
1150 Predicting yield traits of individual field-grown Brassica napus plants from rosette-stage leaf gene expression
De Meyer, S.; Cruz, D. F.; De Swaef, T.; Lootens, P.; De Block, J.; Bird, K.; Sprenger, H.; Van de Voorde, M.; Hawinkel, S.; Van Hautegem, T.; Inze, D.; Nelissen, H.; Roldan-Ruiz, I.; Maere, S.
10.1101/2022.10.21.513275 — systems biology — Posted on 2022-10-23
1151 Methods for Evaluating Effects of Transgenes for Quantitative Traits
Linares, J. F.; Coles, N. D.; Mo, H.; Habben, J. E.; Humbert, S.; Messina, C.; Tang, T.; Cooper, M.; Gho, C.; Carrasco, R.; Carter, J.; Flounders, J.; Brummer, E. C.
10.1101/2022.10.22.513367 — plant biology — Posted on 2022-10-23
1152 Transgene by Germplasm Interactions Can Impact Transgene Evaluation
Linares, J. F.; Coles, N. D.; Mo, H.; Habben, J. E.; Humbert, S.; Messina, C.; Tang, T.; Cooper, M.; Gho, C.; Carrasco, R.; Carter, J.; Flounders, J.; Brummer, E. C.
10.1101/2022.10.22.513364 — plant biology — Posted on 2022-10-23
1153 Spatially controlled microtubule nucleation and organization from crosslinker MAP65 condensates
Sahu, S.; Chauhan, P.; Lumen, E.; Moody, K.; Peddireddy, K.; Mani, N.; Subramanian, R.; Robertson-Anderson, R. M.; Wolfe, A.; Ross, J. L.
10.1101/2022.10.23.513406 — biophysics — Posted on 2022-10-23
1155 PhISCO: a simple method to infer phenotypes from protein sequences
Berthet, A. S. H.; Aptekmann, A. A.; bravo, j. t.; Sanchez, I. E.; Noguera, M. E.; Roman, E. A.
10.1101/2022.10.23.511734 — biophysics — Posted on 2022-10-23
1160 Distinction between small RNA-bound and free ARGONAUTE via an N-terminal protein-protein interaction site
Bressendorff, S.; Sjogaard, I. M. Z.; Oksbjerg, E. D.; Kausika, S.; Michels, A.; Prestel, A.; Kragelund, B. B.; Poulsen, C.; Brodersen, P.
10.1101/2022.10.22.513346 — molecular biology — Posted on 2022-10-23
1164 Glycoengineered keratinocyte library reveals essential functions of specific glycans for all stages of HSV-1 life cycle
Bagdonaite, I.; Marinova, I. N.; Rudjord-Levann, A. M.; Pallesen, E. M.; King-Smith, S.; Roemer, T. B.; Chen, Y.-H.; Dabelsteen, S.; Wandall, H. H.
10.1101/2022.10.23.513399 — microbiology — Posted on 2022-10-23
1165 C-4-Modified Isotetrones Prevent Biofilm Growth and Persister Cell Resuscitation in Mycobacterium smegmatis
Bag, K.; Pal, A.; Basu, S.; Singla, M.; Chatterji, D.; Maiti, P. K.; Ghosh, A.; Jayaraman, N.
10.1101/2022.10.23.513374 — microbiology — Posted on 2022-10-23
1169 A quantitative model for the transcriptional landscape of the bacterial cell cycle
Pountain, A.; Jiang, P.; Podkowik, M.; Shopsin, B.; Torres, V. J.; Yanai, I.
10.1101/2022.10.22.513359 — systems biology — Posted on 2022-10-23
1170 Anti-Inflammatory Tension-Activated Repair Patches Improve Repair After Intervertebral Disc Herniation
Peredo, A. P.; Gullbrand, S. E.; Friday, C. S.; Orozco, B. S.; Bonnevie, E. D.; Hilliard, R. L.; Zlotnick, H. M.; Dodge, G. R.; Lee, D.; Hast, M. W.; Schaer, T. P.; Smith, H. E.; Mauck, R.
10.1101/2022.10.22.513360 — bioengineering — Posted on 2022-10-23
1176 Prioritizing landscapes to reconcile biodiversity conservation, ecosystem services, and human well-being in India
Srivathsa, A.; Vasudev, D.; Nair, T.; Chakrabarti, S.; Chanchani, P.; DeFries, R.; Deomurari, A.; Dutta, S.; Ghose, D.; Goswami, V.; Nayak, R.; Neelakantan, A.; Thatte, P.; Vaidyanathan, S.; Verma, M.; Krishnaswamy, J.; Sankaran, M.; Ramakrishnan, U.
10.1101/2022.08.27.505513 — ecology — Posted on 2022-10-23
1177 Carboxylic acids that drive mosquito attraction to humans activate ionotropic receptors
Ray, G.; Huff, R. M.; Castillo, J. S.; Bellantuono, A. J.; DeGennaro, M.; Pitts, J.
10.1101/2022.10.20.513041 — molecular biology — Posted on 2022-10-23
1178 Two Synaptic Convergence Motifs Define Functional Roles for Inputs to Cochlear Nucleus Bushy Cells
Spirou, G. A.; Kersting, M.; Carr, S.; Razzaq, B.; Alves-Pinto, C. Y.; Dawson, M.; Ellisman, M. H.; Manis, P. B.
10.1101/2022.09.10.507000 — neuroscience — Posted on 2022-10-23
1179 In-vivo fast non-linear microscopy reveals impairment of fast axonal transport induced by molecular motor imbalances in the brain of zebrafish larvae
GRIMAUD, B.; FRETAUD, M.; TERRAS, F.; BENASSY, A.; DUROURE, K.; BERCIER, V.; TRIPPE-ALLARD, G.; MOHAMMEDI, R.; GACOIN, T.; Del Bene, F.; MARQUIER, F.; LANGEVIN, C.; TREUSSART, F.
10.1101/2022.07.09.499436 — neuroscience — Posted on 2022-10-23
1180 Regulation of adventitial interstitial fluid circulation by heartbeat and respiration
Li, H.; Li, B.; Luo, W.; Qi, X.; Hao, Y.; Yang, C.; Li, W.; Li, J.; Hua, Z.; Guo, T.; Zheng, Z.; Wang, X.; Yu, X.; Lv, X.; Huang, D.; Hu, J.; Li, Z.; Wang, F.; Li, H.; Ma, C.; Ji, F.
10.1101/2022.10.18.512678 — physiology — Posted on 2022-10-23
1181 DNA Methylation Signatures in Breast Cancer: A Systematic Review and Meta-Analysis
Trasierras-Fresco, A. M.; Andreu, Z.; Hidalgo, M. R.; Gomez-Cabanes, B.; Malmierca-Merlo, P.; Romera-Giner, S.; Crespo, D.; Gomez-Martinez, H.; Serna-Blasco, R.; Romero, A.; Lopez-Guerrero, J. A.; de la Iglesia Vaya, M.; Garcia-Garcia, F.
10.1101/2022.10.15.512358 — cancer biology — Posted on 2022-10-23
1186 A ten-year community reporting database reveals rising coyote boldness and associated human concern in Edmonton, Canada
Farr, J. J.; Pruden, M. J.; Glover, R.; Murray, M.; Sugden, S. A.; Harshaw, H. W.; Cassady St. Clair, C.
10.1101/2022.10.18.512552 — ecology — Posted on 2022-10-23
1187 Influence of circular RNA topology on microRNA stability
Fuchs Whightman, F.; Lukin, J.; Giusti, S.; Soutschek, M.; Bragado, L.; Pozzi, B.; Gonzalez, P.; Fededa, J. P.; Schratt, G.; Refojo, D.; de la Mata, M.
10.1101/2022.04.11.487822 — molecular biology — Posted on 2022-10-23
1193 Differential Regulation of mTor signaling defines subtypes of cblX syndrome
Castro, V. L.; Paz, D.; Esteveo, I.; Grajeda, B. I.; Ellis, C. C.; Quintana, A. M.
10.1101/2022.10.21.513292 — developmental biology — Posted on 2022-10-22
1194 DNA methylation restricts coordinated germline and neural fates in embryonic stem cell differentiation
Schulz, M.; Teissandier, A.; de la Mata-Santaella, E.; Armand, M.; Iranzo, J.; El Marjou, F.; Gestraud, P.; Walter, M.; Kinston, S.; Göttgens, B.; Greenberg, M. V. C.; Bourc'his, D.
10.1101/2022.10.22.513040 — developmental biology — Posted on 2022-10-22
1196 Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis
Delbeau, M.; Omollo, E. O.; Froom, R.; Koh, S.; Mooney, R. A.; Lilic, M.; Brewer, J. J.; Rock, J.; Darst, S. A.; Campbell, E. A.; Landick, R.
10.1101/2022.10.21.513233 — molecular biology — Posted on 2022-10-22
1197 The cellular Notch1 Protein Promotes KSHV reactivation in an Rta-dependent manner.
DeCotiis-Mauro, J.; Han, S. M.; Mello, H.; Goyeneche, C.; Marchesini-Tovar, G.; Jin, L.; Bellofatto, V.; Lukac, D. M.
10.1101/2022.10.21.513206 — microbiology — Posted on 2022-10-22
1199 The Western Lake Erie Culture Collection: A promising resource for evaluating the physiological and genetic diversity of Microcystis and its associated microbiome
Yancey, C. E.; Kiledal, E. A.; Denef, V. J.; Errera, R. M.; Evans, J. T.; Hart, L.; Isailovic, D.; James, W.; Kharbush, J. J.; Kimbrel, J. A.; Li, W.; Mayali, X.; Nitschky, H.; Polik, C.; Powers, M. A.; Premathilaka, S. H.; Rappuhn, N.; Reitz, L. A.; Rivera, S. R.; Zwiers, C. C.; Dick, G. J.
10.1101/2022.10.21.513177 — microbiology — Posted on 2022-10-22
1202 Bacterial aerobic methane cycling by the marine sponge-associated microbiome
Ramirez, G. A.; Bar-Shalom, R.; Furlan, A.; Romeo, R.; Gavagnin, M.; Calabrese, G.; Garber, A. I.; Steindler, L.
10.1101/2022.10.21.513280 — microbiology — Posted on 2022-10-22
1205 The NQR pathway regulates the immunomodulatory function of Bacteroides thetaiotaomicron
Engelhart, M. J.; Glowacki, R. W.; Harding, C. V.; Martens, E. C.; Ahern, P. P.
10.1101/2022.10.21.513251 — microbiology — Posted on 2022-10-22
1206 T cell subsets in chronic hepatitis C patients genotype 4 who achieved SVR following DAAs Therapy
Shiha, G.; Soliman, R.; Hassan, A.; Mikhail, N.; Nabil, A.; Saleh, L.; Sayed, D.; Eslam, M.
10.1101/2022.10.21.513286 — immunology — Posted on 2022-10-22
1208 Brain DNA methylomic analysis of frontotemporal lobar degeneration reveals OTUD4 and CEBPZ in shared dysregulated signatures across pathological subtypes
Fodder, K.; Murthy, M.; Rizzu, P.; Toomey, C. E.; Hasan, R.; Humphrey, J.; Raj, T.; Lunnon, K.; Mill, J.; Heutink, P.; Lashley, T.; Bettencourt, C.
10.1101/2022.10.21.513088 — neuroscience — Posted on 2022-10-22
1209 O2 photoreduction at acceptor side of Photosystem I provide photoprotection to conifer thylakoids in early spring
Bag, P.; Shutova, T.; Shevela, D.; Lihavainen, J.; Nanda, S.; Ivanov, A. G.; Messinger, J.; Jansson, S.
10.1101/2022.10.21.513261 — plant biology — Posted on 2022-10-22
1210 Barley MLA3 recognizes the host-specificity determinant PWL2 from rice blast (M. oryzae)
Brabham, H. J.; Gomez De La Cruz, D.; Were, V.; Shimizu, M.; Saitoh, H.; Hernandez-Pinzon, I.; Green, P.; Lorang, J.; Fujisaki, K.; Sato, K.; Molnar, I.; Simkova, H.; Dolezel, J.; Russell, J.; Taylor, J.; Smoker, M.; Gupta, Y. K.; Wolpert, T.; Talbot, N. J.; Terauchi, R.; Moscou, M. J.
10.1101/2022.10.21.512921 — plant biology — Posted on 2022-10-22
1211 Influence of MUC1 on trafficking of TRPV5 and TRPV6 and in vivo Ca2+ homeostasis.
Al-Bataineh, M. M.; Kinlough, C. L.; Marciszyn, A. L.; Lam, T.; Ye, L.; Kidd, K.; Maggiore, J. C.; Poland, P. A.; Bleyer, A.; Bain, D. J.; Kleyman, T. R.; Hughey, R. P.; Ray, E. C.
10.1101/2022.10.22.513333 — physiology — Posted on 2022-10-22
1214 Genetic polymorphisms lead to major, locus-specific, variation in piRNA production in mouse.
Casas, E.; Sierra, P.; Moreta-Moraleda, C.; Cebria, J.; Panzeri, I.; Pospisilik, J. A.; Jimenez-Chillaron, J. C.; Forcales, S. V.; Vavouri, T.
10.1101/2022.10.21.513296 — genomics — Posted on 2022-10-22
1215 Loss of altruism in the social amoeba Dictyostelium discoideum is associated with the G protein-coupled receptor, grlG
Walker, L. M.; Sherpa, R. N.; Ivaturi, S.; Brock, D. A.; Walker, J. R.; Strassmann, J. E.; Queller, D. C.
10.1101/2022.10.21.513250 — evolutionary biology — Posted on 2022-10-22
1217 Neuronal birthdate reveals topography in a vestibular brainstem circuit for gaze stabilization
Goldblatt, D.; Huang, S.; Greaney, M. R.; Hamling, K. R.; Voleti, V.; Perez-Campos, C.; Patel, K. B.; Li, W.; Hillman, E. M. C.; Bagnall, M. W.; Schoppik, D.
10.1101/2022.10.21.513243 — neuroscience — Posted on 2022-10-22
1218 Clustering of CaV1.3 L-type calcium channels by Shank3
Yang, Q.; Perfitt, T. L.; Quay, J.; Hu, L.; Colbran, R. J.
10.1101/2022.10.21.513252 — neuroscience — Posted on 2022-10-22
1219 Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation
Chen, X.; Li, Y.; Xu, J.; Cui, Y.; Wu, Q.; Yin, H.; Li, Y.; Jiang, L.; Wang, H.; Wen, Z.; Yao, Z.; Wu, Z.
10.1101/2022.10.22.513336 — developmental biology — Posted on 2022-10-22
1222 R-loop editing by DNA cytosine deaminase APOBEC3B determines the activity of estrogen receptor enhancers
Zhang, C.; LU, Y.-j.; Chen, B.; Bai, Z.; Hervieu, A.; Licciardello, M. P.; Wang, M.; Mitsopoulos, K.; Al-Lazikani, B. P.; Tortorici, M.; Rossanese, O.; Workman, P.; Clarke, P. A.
10.1101/2022.10.21.513235 — cancer biology — Posted on 2022-10-22
1224 Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for co-receptor discrimination
Tsutsumi, N.; Hwang, S.; Hansen, S.; Waghray, D.; Wang, N.; Miao, Y.; Glassman, C. R.; Caveney, N. A.; Jude, K. M.; Janda, C. Y.; Hannoush, R.; Garcia, K. C.
10.1101/2022.10.21.513178 — biophysics — Posted on 2022-10-22
1226 Multi-dimensional protein solubility optimization with an ultra-high-throughput microfluidic platform
Erkamp, N. A.; Oeller, M.; Sneideris, T.; Ausserwoger, H.; Levin, A.; Welsh, T. J.; Qi, R.; Qian, D.; ZHU, H.; Sormanni, P.; Vendruscolo, M.; Knowles, T.
10.1101/2022.10.21.513267 — biophysics — Posted on 2022-10-22
1228 The mechanism of nicotinamide phosphoribosyltransferase whereby positive allosteric modulation elevates cellular NAD+
Ratia, K. M.; Shen, Z.; Gordon-Blake, J.; Lee, H.; Laham, M. S.; Krider, I. S.; Christie, N.; Ackerman-Berrier, M. S.; Penton, C.; Knowles, N. G.; Musku, S. R.; Fu, J.; Musku, G. R.; Xiong, R.; Thatcher, G. R. J.
10.1101/2022.10.21.513220 — biochemistry — Posted on 2022-10-22
1231 Progressive decline in the levels of six miRNAs from parents to children in autism
Mehmetbeyoglu, E.; Yilmaz, Z.; Taheri, S.; Ozkul, Y.; Rassoulzadegan, M.
10.1101/2022.10.20.512859 — genetics — Posted on 2022-10-22
1232 Hidden endosymbionts: A male-killer concealed by another endosymbiont and a nuclear suppressor
Richardson, K. M.; Ross, P. A.; Cooper, B. S.; Conner, W. R.; Schmidt, T.; Hoffmann, A. A.
10.1101/2022.10.19.512817 — evolutionary biology — Posted on 2022-10-22
1234 Multimodal mapping of cell types and projections in the central nucleus of the amygdala
Wang, Y.; Krabbe, S.; Eddison, M.; Henry, F.; Fleishman, G.; Lemire, A. L.; Wang, L.; Korff, W.; Tillberg, P.; Lüthi, A.; Sternson, S.
10.1101/2022.10.19.512845 — neuroscience — Posted on 2022-10-22
1235 Predictive Network Analysis Identifies JMJD6 and Other Novel Key Drivers in Alzheimer Disease
Merchant, J. P.; Zhu, K.; Henrion, M. Y. R.; Zaidi, S. S. A.; Branden, L.; Moein, S.; Alamprese, M. L.; Pearse, R. V.; Bennett, D. A.; Ertekin-Taner, N.; Young-Pearse, T. L.; Chang, R.
10.1101/2022.10.19.512949 — neuroscience — Posted on 2022-10-22
1236 Metabolic intervention that reduces glucose-insulin signaling suppresses the onset and progression of neuroendocrine tumors
Ohki, R.; Chen, Y.; Sada, A.; Tabata, Y.; Moro, T.; Sakaguchi, Y.; Tajima, T.; Takahashi, Y.; Yokoyama, A.; Hijioka, S.
10.1101/2022.10.21.507065 — cancer biology — Posted on 2022-10-22
1237 A peptide strategy for inhibiting different protein aggregation pathways in disease
Garfagnini, T.; Ferrari, L.; Koopman, M.; Halters, S.; Van Kappel, E.; Mayer, G.; Maurice, M.; Rudiger, S.; Friedler, A.
10.1101/2022.10.22.513060 — biochemistry — Posted on 2022-10-22
1238 QClus: Robust and reliable preprocessing method for human heart snRNA-seq
Schmauch, E.; Ojanen, J.; Galani, K.; Jalkanen, J.; Hollmen, M.; Gunn, J.; Kiviniemi, T.; Kellis, M.; Linna-Kuosmanen, S.
10.1101/2022.10.21.513315 — genomics — Posted on 2022-10-22
1240 Molecular early burst associated with the diversification of birds at the K-Pg boundary
Berv, J. S.; Singhal, S.; Field, D. J.; Walker-Hale, N.; McHugh, S. W.; Shipley, J. R.; Miller, E. T.; Kimball, R. T.; Braun, E. L.; Dornburg, A.; Parins-Fukuchi, C. T.; Prum, R. O.; Friedman, M.; Smith, S. A.
10.1101/2022.10.21.513146 — evolutionary biology — Posted on 2022-10-22
1242 Spatiotemporal dynamics during niche remodeling by super-colonizing microbiota in the mammalian gut
Urtecho, G.; Moody, T. M.; Huang, Y.; Sheth, R. U.; Richardson, M.; Lekan, O.; Velez-Cortes, F.; Ricaurte, D.; Wang, H. H.
10.1101/2022.10.21.513299 — microbiology — Posted on 2022-10-22
1244 Distinct tumor-immune ecologies in NSCLC patientspredict progression and define a clinical biomarker of therapy response
Prabhakaran, S.; Gatenbee, C.; Robertson-Tessi, M.; Beg, A. A.; Gray, J.; Antonia, S.; Gatenby, R. A.; Anderson, A. R. A.
10.1101/2022.10.22.513219 — cancer biology — Posted on 2022-10-22
1247 Comprehensive SMN1 and SMN2 profiling for spinal muscular atrophy analysis using long-read PacBio HiFi sequencing
Chen, X.; Harting, J.; Farrow, E.; Thiffault, I.; Kasperaviciute, D.; Hoischen, A.; Gilissen, C.; Pastinen, T.; Eberle, M. A.
10.1101/2022.10.19.512930 — genetics — Posted on 2022-10-22
1248 Systematic loss of function screens identify pathway specific functional circular RNAs
Liu, L.; Neve, M.; Perlaza-Jimenez, L.; Hawdon, A.; Conn, S.; Zenker, J.; Tamayo, P.; Goodall, G.; Rosenbluh, J.
10.1101/2022.10.22.513321 — genetics — Posted on 2022-10-22
1249 In vivo proximity ligation reveals endogenous candidate interactors of Neurexin's intracellular domain
Schaan Profes, M.; Tiroumalechetty, A.; Patel, N.; Lauar, S. S.; Sidoli, S.; Kurshan, P. T.
10.1101/2022.09.27.509791 — neuroscience — Posted on 2022-10-22
1252 Differences in the structure of plant polygalacturonases specify enzymes dynamics and processivities to fine-tune cell wall pectins
Safran, J.; Tabi, W.; Ung, V.; Lemaire, A.; Habrylo, O.; Bouckaert, J.; Rouffle, M.; Voxeur, A.; Pongrac, P.; Bassard, S.; Molinie, R.; Fontaine, J.-X.; Pilard, S.; Pau-Roblot, C.; Bonnin, E.; Larsen, D. S.; Morel-Rouhier, M.; Girardet, J.-M.; LEFEBVRE, V.; Senechal, F.; Mercadante, D.; PELLOUX, J.
10.1101/2022.06.22.497136 — biochemistry — Posted on 2022-10-22
1255 Nitrogenase resurrection and the evolution of a singular enzymatic mechanism
Garcia, A. K.; Harris, D.; Rivier, A.; Carruthers, B.; Barros, A. P.; Seefeldt, L.; Kacar, B.
10.1101/2022.05.17.492308 — evolutionary biology — Posted on 2022-10-22
1259 Druggable redox pathways against M. abscessus in cystic fibrosis patient-derived airway organoids
Leon Icaza, S. A.; Bagayoko, S.; VERGE, R.; Iakobachvili, N.; Ferrand, C.; Aydogan, T.; Bernard, C.; Sanchez Dafun, A.; Murris-Espin, M.; Mazieres, J.; Bordignon, P. J.; Mazeres, S.; Bernes Lasserre, P.; Rame, V.; Lagarde, J.-M.; Marcoux, J.; Bousquet, M. P.; Chalut, C.; Guilhot, C.; Clevers, H.; Peters, P. J.; Molle, V.; Lugo-Villarino, G.; Cam, K.; Berry, L.; Meunier, E.; Cougoule, C.
10.1101/2022.01.03.474765 — cell biology — Posted on 2022-10-22
1261 Control of pancreatic islet function and glucose homeostasis by a novel microexon program misregulated in type 2 diabetes
Juan-Mateu, J.; Bajew, S.; Miret-Cuesta, M.; Iniguez, L. P.; Lopez-Pascual, A.; Bonnal, S.; Atla, G.; Bonas-Guarch, S.; Ferrer, J.; Valcarcel, J.; Irimia, M.
10.1101/2022.04.02.486809 — molecular biology — Posted on 2022-10-22
1262 Sphingolipids protect ergosterol in the Leishmania major membrane from sterol-binding toxins
Haram, C.; Moitra, S.; Keane, R.; Kuhlmann, F. M.; Frankfater, C.; Hsu, F.-f.; Beverley, S. M.; Zhang, K.; Keyel, P. A.
10.1101/2022.06.15.496300 — microbiology — Posted on 2022-10-22
1264 Gene regulatory network inference in soybean upon infection by Phytophthora sojae
Hale, B.; Ratnayake, S.; Flory, A.; Wijeratne, R.; Schmidt, C.; Robertson, A.; Wijeratne, A.
10.1101/2022.10.19.512983 — plant biology — Posted on 2022-10-22
1265 Cell surface receptor kinase FERONIA linked to nutrient sensor TORC signaling controls root hair growth at low temperature linked to low nitrate in Arabidopsis thaliana
Pacheco, J. M.; Song, L.; Kubenova, L.; Ovecka, M.; Gabarain, V. B.; Peralta, J. M.; Lehuede, T. U.; Ibeas, M. A.; Ricardi, M. M.; Zhu, S.; Shen, Y.; Schepetilnikov, M.; Ryabova, L.; Alvarez, J.; Gutierrez, R. A.; Grossmann, G.; Samaj, J.; Yu, F.; Estevez, J. M.
10.1101/2022.01.10.475584 — plant biology — Posted on 2022-10-22
1267 Unifying the Identification of Biomedical Entities with the Bioregistry
Hoyt, C. T.; Balk, M.; Callahan, T. J.; Domingo-Fernandez, D.; Haendel, M. A.; Hegde, H. B.; Himmelstein, D. S.; Karis, K.; Kunze, J.; Lubiana, T.; Matentzoglu, N.; McMurry, J.; Moxon, S.; Mungall, C. J.; Rutz, A.; Unni, D. R.; Willighagen, E.; Winston, D.; Gyori, B. M.
10.1101/2022.07.08.499378 — bioinformatics — Posted on 2022-10-22
1269 Uneven terrain treadmill walking in younger and older adults
Downey, R. J.; Richer, N.; Gupta, R.; Liu, C.; Pliner, E. M.; Roy, A.; Hwang, J.; Clark, D. J.; Hass, C. J.; Manini, T. M.; Seidler, R. D.; Ferris, D. P.
10.1101/2022.03.01.482507 — bioengineering — Posted on 2022-10-22
1270 Restriction of access to the central cavity is a major contributor to substrate selectivity in plant ABCG transporters
Pakuła, K.; Sequeiros-Borja, C.; Biała-Leonhard, W.; Pawela, A.; Banasiak, J.; Bailly, A.; Radom, M.; Geisler, M.; Brezovsky, J.; Jasinski, M.
10.1101/2022.08.16.503940 — biochemistry — Posted on 2022-10-22
1274 A latitudinal pattern of plant leaf-associated bacterial community assembly
Wang, Z.; Jiang, Y.; Zhang, M.; Chu, C.; Chen, Y.; Fang, S.; Jin, G.; Jiang, M.; Lian, J.; Li, Y.; Liu, Y.; Ma, K.; Mi, X.; Qiao, X.; Wang, X.; Wang, X.; Xu, H.; Ye, W.; Zhu, L.; Zhu, Y.; He, F.; Kembel, S. W.
10.1101/2022.06.23.497395 — ecology — Posted on 2022-10-22
1277 Myeloid deficiency of the intrinsic clock protein Bmal1 accelerates cognitive aging by disrupting microglial synaptic pruning
Iweka, C. A.; Seigneur, E. M.; Hernandez, A. L.; Herrera Paredes, S.; Cabrera, M.; Blacher, E.; Pasternak, C.; Longo, F.; de Lecea, L.; Andreasson, K.
10.1101/2022.10.17.512618 — neuroscience — Posted on 2022-10-22
1280 Tmem117 in AVP neurons regulates the counterregulatory response to hypoglycemia
Gaspari, S.; Labouebe, G.; Picard, A.; Berney, X. P.; Rodriguez Sanchez-Archidona, A.; Thorens, B.
10.1101/2022.10.21.513159 — physiology — Posted on 2022-10-21
1281 Non-invasive muscle biopsy: estimation of muscle fibre size from a neuromuscular interface
Casolo, A.; Maeo, S.; Balshaw, T. G.; Lanza, M. B.; Martin, N. R. W.; Nuccio, S.; Moro, T.; Paoli, A.; Felici, F.; Maffulli, N.; Eskofier, B.; Kinfe, T. M.; Folland, J. P.; Farina, D.; Del Vecchio, A.
10.1101/2022.10.21.513157 — physiology — Posted on 2022-10-21
1285 From genome wide SNPs to genomic islands of differentiation: the quest for species diagnostic markers in two scleractinian corals, Pocillopora and Porites
Deshuraud, R.; Ottaviani, A.; Poulain, J.; Lepretre, M.; Beluche, O.; Mahieu, E.; Lebled, S.; Belser, C.; Rouan, A.; Moulin, C.; Boissin, E.; Bourdin, G.; Iwankow, G.; Romac, S.; Agostini, S.; Banaigs, B.; Boss, E. S.; Bowler, C.; de Vargas, C.; Douville, E.; Flores, M.; Furla, P.; Galand, P.; Lombard, F.; Pesant, S.; Reynaud, S.; Sullivan, M. B.; Sunagawa, S.; Thomas, O.; Trouble, R.; Thurber, R. V.; Voolstra, C. R.; Wincker, P.; Zoccola, D.; Planes, S.; Allemand, D.; Gilson, E.; Forcioli, D.
10.1101/2022.10.21.513203 — evolutionary biology — Posted on 2022-10-21
1288 Parsing brain-behavior heterogeneity in very preterm born children using integrated similarity networks
Hadaya, L.; Dimitrakopoulou, K.; Vanes, L. D.; Kanel, D.; Fenn-Moltu, S.; Gale-Grant, O.; Counsell, S.; Edwards, A. D.; Saqi, M.; Batalle, D.; Nosarti, C.
10.1101/2022.10.20.513074 — neuroscience — Posted on 2022-10-21
1291 RALF peptides modulate immune response in the moss Physcomitrium patens
Mamaeva, A.; Lyapina, I.; Knyazev, A.; Golub, N.; Mollaev, T.; Chudinova, E.; Elansky, S.; Babenko, V.; Veselovsky, V.; Klimina, K.; Gribova, T.; Kharlampieva, D.; Lazarev, V.; Fesenko, I.
10.1101/2022.10.21.513210 — plant biology — Posted on 2022-10-21
1296 Extracellular matrix flow guides in-vitro epithelial morphogenesis
Fattah, A. R. A.; Sgualdino, F.; Poovathingal, S.; Davie, K.; Baatsen, P.; Vints, K.; Gunko, N.; Ranga, A.
10.1101/2022.10.21.513217 — bioengineering — Posted on 2022-10-21
1298 Pseudogenes limit the identification of novel common transcripts generated by their parent genes
Gustavsson, E. K.; Sethi, S.; Gao, Y.; Brenton, J.; Garcia Ruiz, S.; Zhang, D.; Garza, R.; Reynolds, R. H.; Evans, J. R.; Chen, Z.; Grant-Peters, M.; MacPherson, H.; Montgomery, K.; Dore, R.; Wernick, A. I.; Arber, C.; Wray, S.; Gandhi, S.; Esselborn, J.; Blauwendraat, C.; Douse, C. H.; Adami, A.; Atacho, D. A. M.; Kouli, A.; Quaegebeur, A.; Barker, R. A.; Englund, E.; Platt, F. M.; Jakobsson, J.; Wood, N. W.; Houlden, H.; Saini, H.; Bento, C. F.; Hardy, J.; Ryten, M.
10.1101/2022.10.21.513169 — genetics — Posted on 2022-10-21
1301 SARS-CoV-2 nsp3-4 suffice to form a pore shaping replication organelles
Zimmermann, L.; Zhao, X.; Makroczyova, J.; Wachsmuth-Melm, M.; Prasad, V.; Bartenschlager, R.; Chlanda, P.
10.1101/2022.10.21.513196 — microbiology — Posted on 2022-10-21
1302 Rapamycin rescues loss-of-function in blood-brain barrier-interacting regulatory T cells
Baeten, P.; Hamad, I.; Hoeks, C.; Hiltensperger, M.; Van Wijmeersch, B.; Popescu, V.; Aly, L.; Somers, V.; Korn, T.; Kleinewietfeld, M.; Hellings, N.; Broux, B.
10.1101/2022.10.21.513147 — immunology — Posted on 2022-10-21
1305 Possible adaption of the 2022 Monkeypox virus to the human host through gene duplication and loss
Brinkmann, A.; Kohl, C.; Pape, K.; Bourquain, D.; Thuermer, A.; Michel, J.; Schaade, L.; Nitsche, A.
10.1101/2022.10.21.512875 — molecular biology — Posted on 2022-10-21
1307 Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: functional regulation of LDLR levels
Fruchart Gaillard, C.; Ben Djoudi Ouadda, A.; Ciccone, L.; Girard, E.; Mikaeeli, S.; Evagelidis, A.; Le Devehat, M.; Susan-Resiga, D.; Cassar Lajeunesse, E.; Nozach, H.; Pereira Ramos, O. H.; Thureau, A.; Legrand, P.; Prat, A.; Dive, V.; Seidah, N. G. G.
10.1101/2022.10.20.513093 — molecular biology — Posted on 2022-10-21
1308 Career Self-Efficacy Disparities in Underrepresented Biomedical Scientist Trainees
Chatterjee, D.; Jacob, G. A.; Sturzenegger Varvayanis, S.; Wefes, I.; Chalkley, R.; Nogueira, A. T.; Fuhrmann, C.; Varadarajan, J.; Hubbard, N. M.; Gaines, C. H.; Layton, R. L.; Chaudhary, S.
10.1101/2022.10.21.512368 — scientific communication and education — Posted on 2022-10-21
1310 Insitutype: likelihood-based cell typing for single cell spatial transcriptomics
Danaher, P.; Zhao, E.; Yang, Z.; Ross, D.; Gregory, M.; Reitz, Z.; Kim, T. K.; Baxter, S.; Jackson, S.; He, S.; Henderson, D. A.; Beechem, J. M.
10.1101/2022.10.19.512902 — bioinformatics — Posted on 2022-10-21
1314 Molecular Basis for Interferon-mediated Pathogen Restriction in Human Cells
Matta, S. K.; Kohio, H. P.; Chandra, P.; Brown, A.; Doench, J. G.; A. Philips, J.; Ding, S.; Sibley, L. D.
10.1101/2022.10.21.513197 — microbiology — Posted on 2022-10-21
1315 A retroviral origin of vertebrate myelin
Ghosh, T.; Almeida, R. G.; Zhao, C.; Mannioui, A.; Martin, E.; Fleet, A.; Gonzalez M, G.; Rowitch, D. H.; Stott, K.; Adams, I.; Zalc, B.; Goldman, N.; Lyons, D. A.; Franklin, R. J.
10.1101/2022.01.24.477350 — neuroscience — Posted on 2022-10-21
1316 Memory phase-specific genes in the Mushroom Bodies identified using CrebB-target DamID
Sgammeglia, N.; Kaldun, J.; Widmer, Y.; Fritsch, C.; Bruggmann, R.; Sprecher, S. G.
10.1101/2022.10.21.512997 — neuroscience — Posted on 2022-10-21
1318 Global landscape of the host response to SARS-CoV-2 variants reveals viral evolutionary trajectories
Bouhaddou, M.; Reuschl, A.-K.; Polacco, B. J.; Thorne, L. G.; Ummadi, M. R.; Ye, C.; Ramirez, R. R.; Pelin, A.; Batra, J.; Jang, G. M.; Xu, J.; Moen, J. M.; Richards, A. L.; Zhou, Y.; Harjai, B.; Stevenson, E.; Rojc, A.; Ragazzini, R.; Whelan, M. V. X.; Furnon, W.; De Lorenzo, G.; Cowton, V.; Syed, A. M.; Ciling, A.; Deutsch, N.; Pirak, D.; Dowgier, G.; Mesner, D.; Turner, J. L.; McGovern, B. L.; Rodriguez, M. L.; Leiva-Rebollo, R.; Dunham, A. S.; Zhong, X.; Eckhardt, M.; Fossati, A.; Liotta, N.; Kehrer, T.; Cupic, A.; Rutkowska, M.; Mena, N.; Aslam, S.; Hoffert, A.; Foussard, H.; Pham, J.; Ly
10.1101/2022.10.19.512927 — systems biology — Posted on 2022-10-21
1320 CWLP and PRP940 form plasma-membrane nanodomain complexes with aquaporins, interact with PP2A and contribute to dehydration tolerance
Honig, A.; Eilenberg, H.; Zuther, E.; Avisar, D.; Erster, O.; Eshkol, G.; Stein, H.; Reznik, N.; Schuster, S.; Belausov, E.; Abu-Abied, M.; Hotta, T.; Lee, Y.-R. J.; Liu, B.; Sadot, E.; Koncz, C.; Zilberstein, A.; Fichman, Y.
10.1101/2022.10.20.512913 — plant biology — Posted on 2022-10-21
1322 Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing and alters beta cell identity in mice
Chen, Y.-C.; Taylor, A. J.; Fulcher, J. M.; Swensen, A. C.; Dai, X.-Q.; Komba, M.; Wrightson, K. L. C.; Fok, K.; Patterson, A. E.; Klein-Geltink, R. I.; MacDonald, P. E.; Qian, W.-J.; Verchere, C. B.
10.1101/2022.10.20.512925 — physiology — Posted on 2022-10-21
1323 Lineage plasticity in SCLC generates non-neuroendocrine cells primed for vasculogenic mimicry
Pearsall, S. M.; Williamson, S. C.; Garcia Marques, F. J.; Humphrey, S.; Hughes, E.; Shue, Y. T.; Bermudez, A.; Frese, K.; Galvin, M.; Carter, M.; Preist, L.; Kerr, A.; Zhou, C.; Oliver, T. G.; Humphries, J. D.; Humphries, M. J.; Blackhall, F.; Cannell, I.; Pitteri, S. J.; Hannon, G. J.; Sage, J.; Simpson, K. L.; Dive, C.
10.1101/2022.10.21.512986 — cancer biology — Posted on 2022-10-21
1324 IL-6/STAT3 signaling drives early-stage pancreatic cancer cachexia via suppressed ketogenesis
Arneson-Wissink, P. C.; Mendez, H.; Pelz, K.; Dickie, J.; Bartlett, A. Q.; Worley, B. L.; Krasnow, S. M.; Eil, R.; Grossberg, A. J.
10.1101/2022.10.18.512778 — cancer biology — Posted on 2022-10-21
1327 Identification of two novel heterodimeric ABC transporters in melanoma: ABCB5β/B6 and ABCB5β/B9
Gerard, L.; Duvivier, L.; Fourrez, M.; Sprimont, L.; Gottesman, M. M.; Gillet, J.-P.
10.1101/2022.10.21.513191 — biochemistry — Posted on 2022-10-21
1328 Cell Surface-localized CsgF Condensate is a Gatekeeper in Bacterial Curli Subunit Secretion
Swasthi, H. M.; Basalla, J. L.; Dudley, C. E.; Vecchiarelli, A. G.; Chapman, M. R.
10.1101/2022.10.20.513119 — biochemistry — Posted on 2022-10-21
1332 Evolutionary Diversification of Methanotrophic Ca. Methanophagales (ANME-1) and Their Expansive Virome
Laso-Perez, R.; Wu, F.; Cremiere, A.; Speth, D. R.; Magyar, J. S.; Krupovic, M.; Orphan, V. J.
10.1101/2022.07.04.498658 — microbiology — Posted on 2022-10-21
1335 The GPI-anchored Ly6 protein Belly roll regulates Drosophila melanogaster escape behaviors by modulating the excitability of nociceptive peptidergic interneurons
Li, K.; Tsukasa, Y.; Kurio, M.; Maeta, K.; Tsumadori, A.; Baba, S.; Nishimura, R.; Murakami, A.; Onodera, K.; Morimoto, T.; Uemura, T.; Usui, T.
10.1101/2022.10.20.513010 — neuroscience — Posted on 2022-10-21
1336 Converging pathways direct synapse elimination through the homeodomain transcriptional regulator DVE-1
Alexander, K. D.; Ramachandran, S.; Lambert, C. M.; Russell, J.; Oliver, D.; Armstrong, W.; Rettler, M.; Doitsidou, M.; Benard, C.; Francis, M. M.
10.1101/2022.10.21.512874 — neuroscience — Posted on 2022-10-21
1339 Cancer-Associated Fibroblasts Regulate Patient-Derived Organoid Drug Responses
Ramos Zapatero, M.; Tong, A.; Sufi, J.; Vlckova, P.; Cardoso Rodriguez, F.; Nattress, C.; Qin, X.; Hochhauser, D.; Krishnaswamy, S.; Tape, C. J.
10.1101/2022.10.19.512668 — cancer biology — Posted on 2022-10-21
1340 Integrated assessment of structure and dynamics of solid proteins via accurate solid-state NMR distance information
Södner, B.; Grohe, K.; Neidig, P.; Auch, J.; Blach, S.; Klein, A.; Vasa, S. K.; Schäfer, L. V.; Linser, R.
10.1101/2022.10.20.513076 — biophysics — Posted on 2022-10-21
1341 Collagen breaks at weak sacrificial bonds taming its mechanoradicals
Rennekamp, B.; Karfusehr, C.; Kurth, M.; Ünal, A.; Riedmiller, K.; Gryn'ova, G.; Hudson, D. M.; Gräter, F.
10.1101/2022.10.17.512491 — biophysics — Posted on 2022-10-21
1343 Multi-histone ChIP-Seq Analysis with DecoDen
Narendra, T.; Visona, G.; Cardona, C. d. J.; Schweikert, G.
10.1101/2022.10.18.512665 — bioinformatics — Posted on 2022-10-21
1345 A Platform-Independent Framework for Phenotyping of Multiplex Tissue Imaging Data
Ahmadian, M.; Rickert, C.; Minic, A.; Wrobel, J.; Bitler, B. G.; Zing, F.; Angelo, M.; Hsieh, E. W.; Ghosh, D.; Jordan, K. R.
10.1101/2022.10.20.510630 — bioinformatics — Posted on 2022-10-21
1347 Efficient minimizer orders for large values of k using minimum decycling sets
Pellow, D.; Pu, L.; Ekim, B.; Kotlar, L.; Berger, B.; Shamir, R.; Orenstein, Y.
10.1101/2022.10.18.512682 — bioinformatics — Posted on 2022-10-21
1348 A Synthetic Stress-relaxing Photoresin for Ultrafast Volumetric Bioprinting
Qiu, W.; Gehlen, J.; Bernero, M.; Gehre, C.; Schadli, G. N.; Muller, R.; Qin, X.-H.
10.1101/2022.10.20.513079 — bioengineering — Posted on 2022-10-21
1351 Inferring assembly-curving trends of bacterial micro-compartment shell hexamers from crystal structure arrangements
Garcia-Alles, L.; Soldan, V.; Custovic, I.; Castano-Cerezo, S.; Balor, S.; Fuentes-Cabrera, M.; Truan, G.; Lesniewska, E.; Reguera, D.
10.1101/2022.10.21.512534 — biochemistry — Posted on 2022-10-21
1352 A Chromosome-length Assembly of the Black Petaltail (Tanypteryx hageni) Dragonfly
Tolman, E.; Beatty, C. D.; Bush, J.; Kohli, M.; Moreno, C. M.; Ware, J. L.; Weber, K. S.; Khan, R.; Maheshwari, C.; Weisz, D.; Dudchenko, O.; Aiden, E. L.; Frandsen, P. B.
10.1101/2022.10.18.512723 — genomics — Posted on 2022-10-21
1353 The chromatin landscape of bryophytes
Hisanaga, T.; Wu, S.; Axelsson, E.; Akimcheva, S.; Dolan, L.; Berger, F.
10.1101/2022.10.21.513199 — genomics — Posted on 2022-10-21
1355 Comprehensive SMN1 and SMN2 profiling for spinal muscular atrophy analysis using long-read PacBio HiFi sequencing
Chen, X.; Harting, J.; Farrow, E.; Thiffault, I.; Kasperaviciute, D.; Hoischen, A.; Gilissen, C.; Pastinen, T.; Eberle, M. A.
10.1101/2022.10.19.512930 — genetics — Posted on 2022-10-21
1357 mRNA therapy restores ureagenesis and corrects glutathione metabolism in argininosuccinic aciduria
Gurung, S.; Timmermand, O. V.; Perocheau, D.; Gil-Martinez, A. L.; Minnion, M.; Touramanidou, L.; Fang, S.; Messina, M.; Khalil, Y.; Barber, A. R.; Edwards, R. S.; Finn, P. F.; Cavedon, A.; Siddiqui, S.; Rice, L.; Martini, P. G. V.; Mills, P. B.; Waddington, S. N.; Gissen, P.; Eaton, S.; Ryten, M.; Feelisch, M.; Frassetto, A.; Witney, T. H.; Baruteau, J.
10.1101/2022.10.19.512931 — genetics — Posted on 2022-10-21
1361 Genomic underpinnings of convergent adaptation to high altitudes for alpine plants
Zhang, X.; Kuang, T.; Dong, W.; Qian, Z.; Zhang, H.; Landis, J. B.; Feng, T.; Li, L.; Sun, Y.; Huang, J.; Deng, T.; Wang, H.; Sun, H.
10.1101/2022.10.20.508685 — evolutionary biology — Posted on 2022-10-21
1363 Genetic architecture of behavioural resilience to ocean acidification
Lehmann, R.; Schunter, C.; Welch, M. J.; Arold, S. T.; Nilsson, G. E.; tegner, j.; Munday, P. L.; Ravasi, T.
10.1101/2022.10.18.512656 — ecology — Posted on 2022-10-21
1366 Metabolic consequences of various fruit-based diets in a generalist insect species
Olazcuaga, L.; Baltenweck, R.; Lemenager, N.; Maia-Grondard, A.; Claudel, P.; Hugueney, P.; Foucaud, J.
10.1101/2022.10.21.513142 — ecology — Posted on 2022-10-21
1367 The male mouse meiotic cilium emanates from the mother centriole at zygotene prior to centrosome duplication
Gomez, R.; Page, J.; Garcia-Gonzalo, F. R.; Hidalgo, I.; Perez-Martin, S.; Lopez-Jimenez, P.
10.1101/2022.10.20.512932 — cell biology — Posted on 2022-10-21
1372 Human Liver Organoids as a Patient-derived Model for HBV Infection and Cellular Response
Lim, C. K.; Romeo, O.; Chilver, A. P.; Tran, B. M.; Flanagan, D.; Kirby, E. N.; Breen, J.; Vincan, E.; Warner, N.; McCartney, E. M.; Van der Hoek, M.; Ruszkiewicz, A.; Tse, E.; Beard, M. R.
10.1101/2022.10.20.513112 — microbiology — Posted on 2022-10-21
1373 Gammaretroviruses, novel viruses and pathogenic bacteria in Australian bats with neurological signs, pneumonia and skin lesions
Van Brussel, K.; Mahar, J. E.; Hall, J.; Bender, H.; Ortiz-Baez, A. S.; Chang, W.-S.; Holmes, E. C.; Rose, K.
10.1101/2022.10.20.513122 — microbiology — Posted on 2022-10-21
1374 A germline-targeting chimpanzee SIV envelope glycoprotein elicits a new class of V2-apex directed cross-neutralizing antibodies
Bibollet-Ruche, F.; Russell, R. M.; Ding, W.; Liu, W.; Li, Y.; Wagh, K.; Wrapp, D.; Habib, R.; Skelly, A. N.; Roark, R. S.; Sherrill-Mix, S.; Wang, S.; Rando, J.; Lindemuth, E.; Cruickshank, K.; Park, Y.; Baum, R.; Connell, A.; Li, H.; Giorgi, E. E.; Song, G. S.; Ding, S.; Finzi, A.; Newman, A.; Hernandez, G. E.; Machiele, E.; Cain, D. W.; Mansouri, K.; Lewis, M. G.; Montefiori, D. C.; Wiehe, K. J.; Alam, S. M.; Teng, I.-T.; Kwong, P. D.; Andrabi, R.; Verkoczy, L.; Burton, D. R.; Korber, B. T.; Saunders, K. O.; Haynes, B. F.; Edwards, R. J.; Shaw, G. M.; Hahn, B. H.
10.1101/2022.10.18.512699 — immunology — Posted on 2022-10-21
1375 Glutarate regulates T cell function and metabolism
Minogue, E. A.; Cunha, P. P.; Quaranta, A.; Zurita, J.; Sah-Teli, S. K.; Wadsworth, B.; Hughes, R.; Grice, G.; Velica, P.; Bargiela, D.; Barbieri, L.; Wheelock, C.; Nathan, J. A.; Karppinen, P.; Foskolou, I. P.; Johnson, R. S.
10.1101/2022.10.20.513065 — immunology — Posted on 2022-10-21
1376 Multi-Omic Analysis of Tyrophagus putrescentiae Reveals Insights into the Allergen Complexity of Storage Mites
Wan, A. T.-Y.; XIONG, Q.; Xiao, X.; Ao, K. F.-K.; Jang, S. W.; Wong, B. S.-H.; Wang, M.; Cao, Q.; Fung, C. S.-H.; Chew, F.-T.; Sun, B.; Ngai, S.-m.; Leung, T.-F.; Jeong, K. Y.; Liu, X.; Tsui, S. K.-W.
10.1101/2022.10.21.513148 — immunology — Posted on 2022-10-21
1379 PMI estimation through metabolomics and potassium analysis on animal vitreous humour
Locci, E.; Stocchero, M.; gottardo, r.; Chighine, A.; De-Giorgio, F.; Ferino, G.; Nioi, M.; Demontis, R.; Tagliaro, F.; d'Aloja, E.
10.1101/2022.10.20.513043 — systems biology — Posted on 2022-10-21
1381 Correcting batch effects in large-scale multiomic studies using a reference-material-based ratio method
Yu, Y.; Zhang, N.; Mai, Y.; Chen, Q.; Cao, Z.; Chen, Q.; Liu, Y.; Ren, L.; Hou, W.; Yang, J.; Hong, H.; Xu, J.; Tong, W.; Shi, L.; Zheng, Y.
10.1101/2022.10.19.507549 — systems biology — Posted on 2022-10-21
1382 Comparison of DNA targeting CRISPR editors in human cells
Huang, H.; Lv, W.; Li, J.; Huang, G.; Tan, Z.; Hu, Y.; Ma, S.; Zhang, X.; Huang, L.; Lin, Y.
10.1101/2022.10.20.513037 — synthetic biology — Posted on 2022-10-21
1384 Plant YTHDF proteins are direct effectors of antiviral immunity against an m6A-containing RNA virus
Martinez-Perez, M.; Aparicio, F.; Arribas-Hernandez, L.; Due Tankmar, M.; Rennie, S.; Brodersen, P.; Pallas, V.
10.1101/2022.10.19.512835 — plant biology — Posted on 2022-10-21
1385 Decoy Receptor Fine-tunes Cytokinin Signaling
Kralova, M.; Kubalova, I.; Hajny, J.; Kubiasova, K.; Gallei, M.; Semeradova, H.; Novak, O.; Benkova, E.; Ikeda, Y.; Zalabak, D.
10.1101/2022.10.20.513092 — plant biology — Posted on 2022-10-21
1386 Disentangling leaf structural and material properties in relation to their anatomical and chemical compositional traits in oaks (Quercus L.)
Alonso-Forn, D.; Sancho-Knapik, D.; Farinas, M. D.; Nadal, M.; Martin-Sanchez, R.; Ferrio, J. P.; Resco de Dios, V.; Peguero-Pina, J. J.; Onoda, Y.; Cavender-Bares, J.; Gomez Alvarez Arenas, T.; Gil-Pelegrin, E.
10.1101/2022.10.21.513225 — plant biology — Posted on 2022-10-21
1387 Gene regulatory network inference in soybean upon infection by Phytophthora sojae
Hale, B.; Ratnayake, S.; Flory, A.; Wijeratne, R.; Schmidt, C.; Robertson, A.; Wijeratne, A.
10.1101/2022.10.19.512983 — plant biology — Posted on 2022-10-21
1388 Regulation and Function of a Polarly Localized Lignin Barrier in the Exodermis
Manzano, C.; Morimoto, K. W.; Shaar-Moshe, L.; Mason, G. A.; Canto Pastor, A.; Gouran, M.; De Bellis, D.; Ursache, R.; Kajala, K.; Sinha, N.; Bailey-Serres, J.; Geldner, N.; Del Pozo, J.; Brady, S.
10.1101/2022.10.20.513117 — plant biology — Posted on 2022-10-21
1389 Resistance exercise protects mice from protein-induced metabolic dysfunction
Trautman, M. E.; Braucher, L. N.; Elliehausen, C.; Zhu, W.; Kumari, S.; Zelenovskiy, E.; Green, M.; Sonsalla, M. M.; Yeh, C.-Y.; Hornberger, T. A.; Konopka, A. R.; Lamming, D.
10.1101/2022.10.18.512689 — physiology — Posted on 2022-10-21
1390 Physiological Changes Associated with Copper Sulfate-Induced Emesis in Felines
Murphey, C. P.; Shulgach, J. A.; Amin, P. R.; Douglas, N. K.; Bielanin, J. P.; Sampson, J. P.; Horn, C. C.; Yates, B. J.
10.1101/2022.10.20.512908 — physiology — Posted on 2022-10-21
1391 Surface-based Characterization of Gastric Anatomy and Motility using Magnetic Resonance Imaging and Neural Ordinary Differential Equation
Wang, X.; Cao, J.; Han, K.; Choi, M.; She, Y.; Scheven, U.; Avci, R.; Du, P.; Cheng, L. K.; Natale, M. R. D.; Furness, J. B.; Liu, Z.
10.1101/2022.10.17.512633 — physiology — Posted on 2022-10-21
1392 Reprogramming M2-polarized patient-derived glioblastoma associated microglia/macrophages via CSF1R inhibition
Fermi, V.; Warta, R.; Rapp, C.; Knoll, M.; Jungwirth, G.; Jungk, C.; Dao Trong, P.; von Deimling, A.; Abdollahi, A.; Unterberg, A.; Herold-Mende, C.
10.1101/2022.10.20.511747 — cancer biology — Posted on 2022-10-21
1393 Reconstructing protein interactions at enhancer-promoter regions in prostate cancer
Armaos, A.; Serra, F.; Nunez Carpintero, I.; Seo, J. H.; Baca, S. C.; Gustincich, S.; Valencia, A.; Freedman, M. L.; Cirillo, D.; Giambartolomei, C.; Tartaglia, G. G.
10.1101/2022.10.20.512998 — cancer biology — Posted on 2022-10-21
1394 MDM2 inhibitors, nutlin-3a and navtemadelin, retain efficacy in human and mouse cancer cells cultured in hypoxia
Lerma Clavero, A.; Lafqvist Boqvist, P.; Ingelshed, K.; Bosdotter, C.; Sedimbi, S.; Jiang, L.; Wermeling, F.; Vojtesek, B.; Lane, D. P.; Kannan, P.
10.1101/2022.10.20.513039 — cancer biology — Posted on 2022-10-21
1395 Assisting walking balance using a bio-inspired exoskeleton controller
Afschrift, M.; Van Asseldonk, E.; Van Mierlo, M.; Bayon, C.; Keemink, A.; Van Der Kooij, H.; De Groote, F.
10.1101/2022.10.19.512851 — biophysics — Posted on 2022-10-21
1396 Quantitative analysis of calcium oxalate monohydrate and dihydrate for elucidating the formation mechanism of calcium oxalate kidney stones
Maruyama, M.; Sawada, K. P.; Tanaka, Y.; Okada, A.; Momma, K.; Nakamura, M.; Mori, R.; Furukawa, Y.; Sugiura, Y.; Tajiri, R.; Taguchi, K.; Hamamoto, S.; Ando, R.; Tsukamoto, K.; Takano, K.; Imanishi, M.; Yoshimura, M.; Yasui, T.; Mori, Y.
10.1101/2022.10.20.513046 — biophysics — Posted on 2022-10-21
1397 Heterogeneous and Surface-Catalyzed Amyloid Aggregation Monitored by Spatially Resolved Fluorescence and Single Molecule Microscopy
Zhou, X.; Wilgaard Sinkjaer, A.; Zhang, M.; Dahl Pinholt, H.; Moerck Nielsen, H.; Haztakis, N. S.; van de Weert, M.; Fodera, V.
10.1101/2022.10.05.510935 — biophysics — Posted on 2022-10-21
1399 TF-Prioritizer: a java pipeline to prioritize condition-specific transcription factors
Hoffmann, M.; Trummer, N.; Jankowski, J.; Lee, H. K.; Willruth, L.-L.; Yuan, K.; Lazareva, O.; Baumgarten, N.; Schmidt, F.; Baumbach, J.; Schulz, M. H.; Blumenthal, D. B.; Hennighausen, L.; List, M.
10.1101/2022.10.19.512881 — bioinformatics — Posted on 2022-10-21
1409 Mode of inhibition of RNase P by gambogic acid and juglone
Wu, N.; Karasik, A.; Kaitany, K.; Koutmos, M.; Fierke, C. A.
10.1101/2022.10.20.512141 — biochemistry — Posted on 2022-10-21
1411 Transcriptome characterization of the common cockle (Cerastoderma edule) after exposure to a Marteilia cochillia outbreak
PARDO, B. G.; FERNANDEZ, C.; PAMPIN, M.; BLANCO, A.; IGLESIAS, D.; CAO, A.; CARBALLAL, M. J.; VILLALBA, A.; Martinez, P.
10.1101/2022.10.18.512677 — genomics — Posted on 2022-10-21
1413 A quantitative, genome-wide analysis in Drosophila reveals transposable elements' influence on gene expression is species-specific
Fablet, M.; Salces-Ortiz, J.; Jacquet, A.; Menezes, B. F.; Dechaud, C.; Veber, P.; Nous, C.; Rebollo, R.; Vieira, C.
10.1101/2022.01.20.477049 — genomics — Posted on 2022-10-21
1414 Divergent functions of two clades of flavodoxin in diatoms mitigate oxidative stress and iron limitation
Graff van Creveld, S.; Coesel, S. N.; Blaskowski, S.; Groussman, R. D.; Schatz, M. J.; Armbrust, E. V.
10.1101/2022.10.18.512804 — evolutionary biology — Posted on 2022-10-21
1417 A developmental program that regulates mammalian organ size offsets evolutionary distance
Shimamura, Y.; Tanaka, J.; Kakiuchi, M.; Sarmah, H.; Miura, A.; Hwang, Y.; Sawada, A.; Ninish, Z.; Yamada, K.; Cai, J. J.; Mori, M.
10.1101/2022.10.19.512107 — evolutionary biology — Posted on 2022-10-21
1418 A ten-year community reporting database reveals rising coyote boldness and associated human concern in Edmonton, Canada
Farr, J. J.; Pruden, M. J.; Glover, R.; Murray, M.; Sugden, S. A.; Harshaw, H. W.; Cassady St. Clair, C.
10.1101/2022.10.18.512552 — ecology — Posted on 2022-10-21
1420 IL-33 induced gene expression in activated Th2 effector cells is dependent on IL-1RL1 haplotype and disease status
Saikumar Jayalatha, A. K.; Ketelaar, M.; Hesse, L.; Badi, Y.; Kermani, N. Z.; Brouwer, S.; Dijk, N.; van den Berge, M.; Guryev, V.; Sayer, I.; Vonk, J.; Adcock, I.; Koppelman, G.; Nawijn, M.
10.1101/2022.10.20.513024 — molecular biology — Posted on 2022-10-21
1422 FANCJ DNA helicase is recruited to the replisome by AND-1 to ensure genome stability
Boavida, A.; Napolitano, L. M. R.; Santos, D.; Cortone, G.; Onesti, S.; Jegadesan, N. K.; Branzei, D.; Pisani, F. M.
10.1101/2022.10.21.513143 — molecular biology — Posted on 2022-10-21
1423 Carboxylic acids that drive mosquito attraction to humans activate ionotropic receptors
Ray, G.; Huff, R. M.; Castillo, J. S.; Bellantuono, A. J.; DeGennaro, M.; Pitts, J.
10.1101/2022.10.20.513041 — molecular biology — Posted on 2022-10-21
1425 Genetic mapping reveals Pou2af2-dependent tuning of tuft cell differentiation and intestinal type 2 immunity
Nadjsombati, M. S.; Niepoth, N.; Webeck, L. M.; Kennedy, E. A.; Jones, D. L.; Baldridge, M. T.; Bendesky, A.; von Moltke, J.
10.1101/2022.10.19.512785 — immunology — Posted on 2022-10-21
1428 A novel method for measuring the priming effect of rewarding brain stimulation
Evangelista, C.; Mehrez, N.; Ewusi Boivert, E.; Brake, W. G.; Shizgal, P.
10.1101/2022.10.20.512941 — neuroscience — Posted on 2022-10-21
1430 Short-range interactions between fibrocytes and CD8+ T cells in COPD bronchial inflammatory response
Eyraud, E.; Maurat, E.; Sac-Epee, J.-M.; Henrot, P.; Zysman, M.; Esteves, P.; Trian, T.; Begueret, H.; Girodet, P.-O.; Thumerel, M.; Hustache-Castaing, R.; Marthan, R.; Levet, F.; Vallois, P.; Contin-Bordes, C.; Berger, P.; Dupin, I.
10.1101/2022.10.21.513138 — pathology — Posted on 2022-10-21
1431 Genetically modified IL-2 bone marrow-derived myeloid cells reprogram the glioma immunosuppressive tumormicroenvironment
Canella, A.; Nazzaro, M.; Rajendran, S.; Schmitt, C.; Haffey, A.; Nigita, G.; Thomas, D.; Wrightnour, H.; Fadda, P.; Mardis, E. R.; Cripe, T. P.; Rajappa, P.
10.1101/2022.10.19.511786 — cancer biology — Posted on 2022-10-21
1432 A mechanistic insight into Nigella sativa mediated anticancer effect on breast cancer through regulation of various miRNAs: An in vitro & in vivo study
DAS, S.; Ghosh, A.; Upadhyay, P.; Sarker, S.; Bhattacharjee, M.; Gupta, P.; Ghosh, S.; Chattopadhyay, S.; Dhar, P.; Adhikary, A.
10.1101/2022.10.18.512670 — cancer biology — Posted on 2022-10-21
1433 Osteosarcoma-enriched transcripts paradoxically generate osteosarcoma-suppressing extracellular proteins
Li, K.; Huo, Q.; Dimmitt, N. H.; Qu, G.; Bao, J.; Pandya, P. H.; Saadatzadeh, M. R.; Bijangi-Vishehsaraei, K.; Kacena, M. A.; Pollok, K. E.; Lin, C.-C.; Li, B.-Y.; Yokota, H.
10.1101/2022.10.18.512687 — cancer biology — Posted on 2022-10-21
1434 ROS induction as a strategy to target persister cancer cells with low metabolic activity in NRAS mutated melanoma
Eichhoff, O. M.; Stoffel, C. I.; Kaesler, J.; Briker, L.; Turko, P.; Karsai, G.; Zila, N.; Paulitschke, V.; Cheng, P. F.; Leitner, A.; Bileck, A.; Zamboni, N.; Irmisch, A.; Balazs, Z.; Tastanova, A.; Pascoal, S.; Johansen, P.; Wegmann, R.; Mena, J.; Othman, A.; Viswanathan, V.; Wenzina, J.; Aloia, A.; Saltari, A.; Dzung, A.; TuPro Consortium, ; Krauthammer, M.; Schreiber, S.; Hornemann, T.; Distel, M.; Snijder, B.; Dummer, R.; Levesque, M.
10.1101/2022.10.19.512839 — cancer biology — Posted on 2022-10-21
1439 DANCE: A Deep Learning Library and Benchmark for Single-Cell Analysis
Ding, J.; Wen, H.; Tang, W.; Liu, R.; Li, Z.; Venegas, J.; Su, R.; Molho, D.; Jin, W.; Zuo, W.; Wang, Y.; Xie, Y.; Tang, J.
10.1101/2022.10.19.512741 — bioinformatics — Posted on 2022-10-21
1441 MSBooster: Improving Peptide Identification Rates using Deep Learning-Based Features
Yang, K. L.; Yu, F.; Teo, G. C.; Demichev, V.; Ralser, M.; Nesvizhskii, A. I.
10.1101/2022.10.19.512904 — bioinformatics — Posted on 2022-10-21
1447 NEMETEX: a Python software for the visualisation of the network of metabolic exchanges
Palamin, M.; Frisinghelli, A.; Offer, E.; Zampieri, G.; Basile, A.; Campanaro, S.
10.1101/2022.10.19.492777 — bioinformatics — Posted on 2022-10-21
1448 The GEN-ERA toolbox: unified and reproducible workflows for research in microbial genomics .
Cornet, L.; Durieu, B.; Baert, F.; D'hooge, E.; Colignon, D.; Meunier, L.; Lupo, V.; Cleenwerck, I.; Daniel, H.-M.; Rigouts, L.; Sirjacobs, D.; Declerck, S.; Vandamme, P.; Wilmotte, A.; Baurain, D.; Becker, P.
10.1101/2022.10.20.513017 — bioinformatics — Posted on 2022-10-21
1450 Elevated oxidative phosphorylation is critical for immune cell activation by polyethylene wear particles
Maduka, C. V.; Kuhnert, M. M.; Habeeb, O. M.; Tundo, A.; Makela, A. V.; Goodman, S. B.; Contag, C. H.
10.1101/2022.10.19.512774 — bioengineering — Posted on 2022-10-21
1456 Hymenoptera (Insecta) telomerase RNAs switched to plant/ciliate-like biogenesis
Fajkus, P.; Adamik, M.; Nelson, A. D. L.; Kilar, A. M.; Franek, M.; Bubenik, M.; Capkova, R. F.; Votavova, A.; Sykorova, E.; Fajkus, J.; Peska, V.
10.1101/2022.10.19.512496 — genomics — Posted on 2022-10-21
1460 A highly contiguous genome assembly reveals sources of genomic novelty in the symbiotic fungus Rhizophagus irregularis
Manley, B. F.; Lotharukpong, J. S.; Barrera-Redondo, J.; Yildirir, G.; Sperschneider, J.; Corradi, N.; Paszkowski, U.; Miska, E. A.; Dallaire, A.
10.1101/2022.10.19.511543 — genomics — Posted on 2022-10-21
1462 Remodeling and compaction of the inactive X is regulated by Xist during female B cell activation
Anguera, M.; Sierra, I.; Nguyen, S. C.; Barnett, R. J.; Cook, A.; Ryu, H.-S.; Beethem, Z.; Phillips-Cremins, J. E.; Joyce, E. F.
10.1101/2022.10.19.512821 — genetics — Posted on 2022-10-21
1463 Searching across-cohort relatives via encrypted genotype regression
Zhang, Q.-X.; Liu, T.; Guo, X.; Zhen, J.; Bao, K.; Yang, M.-y.; Khederzadeh, S.; Zhou, F.; Han, X.; Zheng, Q.; Jia, P.; Ding, X.; He, M.; Zou, X.; Zhang, H.; He, J.; Zhu, X.; Zou, Y.; Lu, S.; Lu, D.; Chen, H.; Zeng, C.; Liu, F.; Zheng, H.-F.; Liu, S.; Xu, H.; Chen, G.-B.
10.1101/2022.10.18.512407 — genetics — Posted on 2022-10-21
1466 High-resolution promoter interaction analysis in Type 3 Innate Lymphoid Cells implicates Batten Disease gene CLN3 in Crohn's Disease aetiology
Malysheva, V.; Ray-Jones, H.; Cazares, T. A.; Clay, O.; Ohayon, D.; Artemov, P.; Wayman, J. A.; Della Rosa, M.; Petitjean, C.; Ellaway, J. I. J.; Orchard, W.; Chen, X.; Parameswaran, S.; Nagano, T.; Fraser, P.; Schoenfelder, S.; Weirauch, M.; Kottyan, L. C.; Smith, D. F.; Powell, N.; Weimer, J.; Wallace, C.; Miraldi, E. R.; Waggoner, S.; Spivakov, M.
10.1101/2022.10.19.512842 — genetics — Posted on 2022-10-21
1467 Diurnality shapes the visual opsin genes of colorful Neotropical frogs
Wan, Y. C.; Navarrete, M. J.; O'Connell, L. A.; Uricchio, L. H.; Roland, A.; Maan, M. E.; Ron, S. R.; Betancourth-Cundar, M.; Pie, M. R.; Howell, K. A.; Richards-Zawacki, C. L.; Cummings, M. E.; Cannatella, D. C.; Santos, J. C.; Tarvin, R. D.
10.1101/2022.10.18.510514 — evolutionary biology — Posted on 2022-10-21
1468 Novel husbandry practices result in rapid rates of growth and sexual maturation without impacting adult behavior in the blind Mexican cavefish.
Kozol, R. A.; Yuiska, A.; Han, J.; Tolentino, B.; Lopatto, A.; Lewis, P.; Paz, A.; Keene, A. C.; Kowalko, J. E.; Duboue, E. R.
10.1101/2022.10.19.512864 — evolutionary biology — Posted on 2022-10-21
1473 High-latitude marginal reefs support fewer but bigger corals than their tropical counterparts
Chong, F.; Sommer, B.; Stant, G.; Verano, N.; Cant, J.; Lachs, L.; Johnson, M. L.; Parsons, D. R.; Pandolfi, J. M.; Salguero-Gomez, R.; Spencer, M.; Beger, M.
10.1101/2022.10.20.513025 — ecology — Posted on 2022-10-21
1478 Synaptotagmin-9 and Tomosyn-1 molecular complex regulates Stx1A SNAREs to inhibit insulin secretion from pancreatic beta-cells
Rahman, M. M.; Pathak, A.; Schueler, K. L.; Alsharif, H. A.; Michl, A. N.; Alexander, J.; Kim, J.-a.; Chapman, E. R.; Bhatnagar, S.
10.1101/2022.10.20.513128 — cell biology — Posted on 2022-10-21
1479 Species-specific roles for the MAFA and MAFB transcription factors in regulatingislet β cell identity
Cha, J.; Tong, X.; Walker, E. M.; Dahan, T.; Cochrane, V.; Ashe, S.; Russell, R.; Osipovich, A. B.; Mawla, A. M.; Guo, M.; Liu, J.-h.; Huising, M. O.; Magnuson, M. A.; Hebrok, M.; Dor, Y.; Stein, R.
10.1101/2022.10.20.512880 — cell biology — Posted on 2022-10-21
1480 Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathy
Liu, S.; Zhao, Y.; Lu, S.; Zhang, T.; Lindenmeyer, M. T.; Nair, V.; Gies, S. E.; Wu, G.; Nelson, R.; Czogalla, J.; Aypek, H.; Zielinski, S.; Liao, Z.; Schape, M.; Fermin, D.; Cohen, C. D.; Delic, D.; Krebs, C. F.; Grahammer, F.; Wiech, T.; Kretzler, M.; Meyer-Schwesinger, C. F.; Bonn, S.; Huber, T. B.
10.1101/2022.10.19.512894 — molecular biology — Posted on 2022-10-21
1484 Tumor infiltrating iNKT cells sustain neutrophil pro-tumorigenic functions influencing disease progression in human colorectal cancer
Lattanzi, G.; Strati, F.; Diaz Basabe, A.; Perillo, F.; Amoroso, C.; Protti, G.; Giuffre, M. R.; Baldari, L.; Cassinotti, E.; Ghidini, M.; Galassi, B.; Lopez, G.; Noviello, D.; Porretti, L.; Trombetta, E.; Mazzarella, L.; Iezzi, G.; Nicassio, F.; Granucci, F.; Caprioli, F.; Facciotti, F.
10.1101/2022.10.19.512854 — immunology — Posted on 2022-10-21
1487 Naturally occurring Alzheimer's disease in rhesus monkeys
Li, Z.; He, X.; Wu, S.; Huang, R.; Li, H.; Wang, Z.; Wang, L.; Qin, D.; Kong, Y.; Guo, Y.; Ma, X.; Turck, C. W.; Xiong, Z.; Wang, W.; Hu, X.
10.1101/2022.10.20.513120 — neuroscience — Posted on 2022-10-21
1488 Huntingtin expression influences spontaneous seizure disorder susceptibility in FVN/B mice
Van Raamsdonk, J.; Al-Shekaili, H.; Wagner, L.; Bredy, T.; Chan, L. L.; Pearson, J.; Schwab, C.; Murphy, Z.; Devon, R. S.; Lu, G.; Kobor, M. S.; Hayden, M. R.; Leavitt, B. R.
10.1101/2022.10.18.512787 — neuroscience — Posted on 2022-10-21
1492 Next-generation ABACUS biosensors reveal cellular ABA dynamics driving root growth at low aerial humidity
Rowe, J.; Grange-Guermente, M.; Exposito-Rodriguez, M.; Wimalasekera, R.; Lenz, M. O.; Shetty, K.; Cutler, S. R.; Jones, A. M.
10.1101/2022.10.19.512731 — plant biology — Posted on 2022-10-21
1494 Regulation of adventitial interstitial fluid circulation by heartbeat and respiration
Li, H.; Li, B.; Luo, W.; Qi, X.; Hao, Y.; Yang, C.; Li, W.; Li, J.; Hua, Z.; Guo, T.; Zheng, Z.; Wang, X.; Yu, X.; Lv, X.; Huang, D.; Hu, J.; Li, Z.; Wang, F.; Li, H.; Ma, C.; Ji, F.
10.1101/2022.10.18.512678 — physiology — Posted on 2022-10-21
1495 Impact of neurons on patient derived-cardiomyocytes using organ-on-a-chip and iPSC biotechnologies
Bernardin, A. A.; Colombani, S.; Rousselot, A.; Andry, V.; Goumon, Y.; Pasqualin, C.; Brugg, B.; Jacotot, E.; Pasquie, J.-L.; Lacampagne, A.; Meli, A. C.
10.1101/2022.10.19.512703 — physiology — Posted on 2022-10-21
1496 Inhibition of GCN5 decreases skeletal muscle fat metabolism during high fat diet feeding
Green, A.; Perras, B. L.; Zhang, H.; Katsyuba, E.; Haboush, A.; Nyarko, K. M.; Pandey, D. K.; Nik-Akhtar, A.; Ryu, D.; Menzies, K. J.; Auwerx, J.
10.1101/2022.10.18.512735 — physiology — Posted on 2022-10-21
1505 Biostatistics and its impact on hazard characterization using in vitro developmental neurotoxicity assays
Kessel, H. E.; Masjosthusmann, S.; Bartmann, K.; Blum, J.; Doenmez, A.; Foerster, N.; Klose, J.; Mosig, A.; Pahl, M.; Leist, M.; Scholze, M.; Fritsche, E.
10.1101/2022.10.18.512648 — bioinformatics — Posted on 2022-10-21
1507 Highly Excretable Gold Supraclusters for Translatable In Vivo Raman Imaging of Tumors
Yu, J. H.; Jeong, M. S.; Cruz, E. O.; Alam, I. S.; Tumbale, S. K.; Zlitni, A.; Lee, S. Y.; Park, Y. I.; Ferrara, K.; Kwon, S.-H.; Gambhir, S. S.; Rao, J.
10.1101/2022.10.18.512314 — bioengineering — Posted on 2022-10-21
1508 Oral Delivery of Kidney Targeting Nanotherapeutics for Polycystic Kidney Disease
Huang, Y.; Wang, J.; Chin, D.; Mancino, V.; Pham, J.; Li, H.; Jiang, K.; Ram, A.; Poon, C.; Ho, P.-Y.; Peti-Peterdi, J.; Gyarmati, G.; Hallows, K. R.; Chung, E. J.
10.1101/2022.10.18.512444 — bioengineering — Posted on 2022-10-21
1511 The genome of Lactuca saligna, a wild relative of lettuce, provides insight into non-host resistance to the downy mildew Bremia lactucae
Xiong, W.; Berke, L.; Michelmore, R.; van Workum, D.-J. M.; Becker, F. F. M.; Schijlen, E.; Bakker, L. V.; Peters, S.; van Treuren, R.; Jeuken, M.; Bouwmeester, K.; Schranz, M. E.
10.1101/2022.10.18.512484 — genomics — Posted on 2022-10-21
1512 High-resolution methylome analysis in the clonal Populus nigra cv. 'Italica' reveals environmentally sensitive hotspots and drought-responsive TE superfamilies
Pena-Ponton, C.; Diez-Rodriguez, B.; Perez-Bello, P.; Becker, C.; McIntyre, L. M.; Van der Putten, W.; De Paoli, E.; Heer, K.; Opgenoorth, L.; Verhoeven, K. J.
10.1101/2022.10.18.512698 — genomics — Posted on 2022-10-21
1513 Multi-trait genome-wide association analyses leveraging alcohol use disorder findings identify novel loci for smoking behaviors in the Million Veteran Program
Cheng, Y.; Dao, C.; Zhou, H.; Li, B.; Kember, R. L.; Toikumo, S.; Zhao, H.; Gelernter, J.; Kranzler, H. R.; Justice, A.; Xu, K.
10.1101/2022.10.18.512710 — genetics — Posted on 2022-10-21
1514 Spatio-temporal modeling of high-throughput multi-spectral aerial images improves agronomic trait genomic prediction in hybrid maize
Morales, N.; Anche, M. T.; Kaczmar, N. S.; Lepak, N.; Ni, P.; Romay, M. C.; Santantonio, N.; Buckler, E. S.; Gore, M. A.; Mueller, L. A.; Robbins, K. R.
10.1101/2022.10.18.512728 — genetics — Posted on 2022-10-21
1518 Dynamics of BMP signaling in the early Drosophila embryo
Al Asafen, H. Y.; Beseli, A.; Hiremath, S. V.; Reeves, G. T.; Williams, C. M.
10.1101/2022.10.20.513072 — developmental biology — Posted on 2022-10-21
1520 TORC1 is an essential regulator of nutrient-dependent differentiation in Leishmania
Myburgh, E.; Geoghegan, V.; Alves-Ferreira, E. V. C.; Nievas, Y. R.; Grewal, J. S.; Brown, E.; McLuskey, K.; Mottram, J. C.
10.1101/2022.10.20.513059 — cell biology — Posted on 2022-10-21
1522 Mitotic chromosomes scale to nucleo-cytoplasmic ratio and cell size in Xenopus
Zhou, C. Y.; Dekker, B.; Liu, Z.; Cabrera, H.; Ryan, J.; Dekker, J.; Heald, R.
10.1101/2022.10.20.513104 — cell biology — Posted on 2022-10-21
1523 Zebrafish Rif1 Impacts Zygotic Genome Activation, Replication Timing, and Sex Determination
Masser, E. A.; Noble, T. D.; Siefert, J. C.; Goins, D.; Sansam, C. G.; Sansam, C. L.
10.1101/2022.10.21.512903 — cell biology — Posted on 2022-10-21
1524 SARS-CoV-2 E and 3a proteins are inducers of pannexin currents
Oliveira Mendes, B.; Alameh, M.; Ollivier, B.; Montnach, J.; Bidere, N.; Souaze, F.; Escriou, N.; Charpentier, F.; Baro, I.; De Waard, M.; Loussouarn, G.
10.1101/2022.10.20.513002 — cell biology — Posted on 2022-10-21
1526 Targeting the Immune-Fibrosis Axis in Myocardial Infarction and Heart Failure
Amrute, J. M.; Luo, X.; Penna, V.; Bredemeyer, A.; Yamawaki, T.; Heo, G. S.; Shi, S.; Koenig, A. L.; Yang, S.; Kadyrov, F. F.; Jones, C.; Kuppe, C.; Kopecky, B.; Hayat, S.; Ma, P.; Feng, G.; Terada, Y.; Fu, A.; Furtado, M.; Kreisel, D.; Stitziel, N. O.; Li, C.-M. K.; Kramann, R.; Liu, Y.; Ason, B.; Lavine, K.
10.1101/2022.10.17.512579 — immunology — Posted on 2022-10-21
1527 PALMO: a comprehensive platform for analyzing longitudinal multi-omics data
Vasaikar, S. V.; Savage, A. K.; Gong, Q.; Swanson, E.; Talla, A.; Lord, C.; Heubeck, A.; Reading, J.; Graybuck, L. T.; Meijer, P.; Torgerson, T. R.; Skene, P.; Bumol, T.; Li, X.-j.
10.1101/2022.10.17.512585 — immunology — Posted on 2022-10-21
1528 The IRE1α-XBP1 signaling axis promotes glycolytic reprogramming in response to inflammatory stimuli
English, B. C.; Savage, H. P.; Mahan, S. P.; Diaz-Ochoa, V. E.; Young, B. M.; Abuaita, B. H.; Sule, G. J.; Knight, J. S.; O'Riordan, M. X.; Baumler, A. J.; Tsolis, R. M.
10.1101/2022.10.19.512943 — immunology — Posted on 2022-10-21
1529 Ripple-locked coactivity of stimulus-specific neurons supports human associative memory
Kunz, L.; Staresina, B. P.; Reinacher, P. C.; Brandt, A.; Guth, T. A.; Schulze-Bonhage, A.; Jacobs, J.
10.1101/2022.10.17.512635 — neuroscience — Posted on 2022-10-21
1533 Vutiglabridin improves neurodegeneration in MPTP-induced Parkinson's disease mice by targeting mitochondrial paraoxonase-2
Kang, S.; Choi, L. S.; Im, S.; Lee, K. W.; Kim, D. H.; Park, J. H.; Park, M.-H.; Lee, J.; Park, S. K.; Kim, K. P.; Lee, H. M.; Jeon, H. J.; Park, H. S.; Yoo, S.-K.; Kim Pak, Y.
10.1101/2022.10.20.512990 — neuroscience — Posted on 2022-10-21
1534 Thousandfold Cell-Specific Pharmacology of Neurotransmission
Shields, B. C.; Yan, H.; Lim, S. S. X.; Burwell, S. C.; Fleming, E. A.; Cammarata, C. M.; Kahuno, E. W.; Vagadia, P. P.; Loughran, M. H.; Zhiquan, L.; McDonnell, M. E.; Scalabrino, M. L.; Thapa, M.; Hawley, T. M.; Reitz, A. B.; Schiltz, G. E.; Hull, C.; Field, G. D.; Glickfeld, L. L.; TADROSS, M. R.
10.1101/2022.10.18.512779 — neuroscience — Posted on 2022-10-21
1536 Novel Master Regulators of Microglial Phagocytosis and Repurposed FDA-approved Drug for Treatment of Alzheimer Disease
Zhu, K.; He, Q.; Tsai, S.-F.; Mudalige, D. M.; Tang, A.; Henrion, M. Y. R.; Liu, Y.; Vijayan, R.; Zaidi, S. S. A.; Branden, L.; Cadiz, M. P.; Hodos-Nkhereanye, R.; Moein, S.; Alamprese, M. L.; Bennett, D. A.; De Jager, P.; Kuo, Y.-M.; Ronaldson, P. T.; Chang, R.
10.1101/2022.10.19.512953 — neuroscience — Posted on 2022-10-21
1538 An armored marine reptile from the Early Triassic of South China
Wolniewicz, A. S.; Shen, Y.; Li, Q.; Sun, Y.; Qiao, Y.; Chen, Y.; Liu, J.
10.1101/2022.10.17.512493 — paleontology — Posted on 2022-10-21
1539 Adipocytes reprogram glucose metabolism in cancer cells promoting metastasis
Mukherjee, A.; Bezwada, D.; Zandbergen, M.; Francesco Greco, F.; Chiang, C.-Y.; Tasdemir, M.; Fahrmann, J.; Grapov, D.; La Frano, M. R.; Vu, H. S.; Newman, J. W.; McDonnell, L. A.; Nezi, L.; Fiehn, O.; DeBerardinis, R. J.; Lengyel, E.
10.1101/2022.10.17.512437 — cancer biology — Posted on 2022-10-21
1540 Thermally Reversible Pattern Formation in Arrays of Molecular Rotors
DeLuca, M.; Pfeifer, W.; Randoing, B.; Huang, C.-M.; Poirier, M. G.; Castro, C.; Arya, G.
10.1101/2022.10.19.512893 — biophysics — Posted on 2022-10-21
1541 A radiofrequency coil for infants and toddlers
Gilbert, K. M.; Nichols, E. S.; Gati, J. S.; Duerden, E. G.
10.1101/2022.10.17.512566 — biophysics — Posted on 2022-10-21
1543 Performance evaluation of mesoscopic photoacoustic imaging
Hacker, L.; Brown, E. L.; Lefebvre, T. L.; Sweeney, P. W.; Bohndiek, S. E.
10.1101/2022.10.17.512521 — bioengineering — Posted on 2022-10-21
1547 Identifying Patients with Cognitive Motor Dissociation Using Resting-state Temporal Stability
Wu, H.; Xie, Q.; Pan, J.; Liang, Q.; Lan, Y.; Guo, Y.; Han, J.; Xie, M.; Liu, Y.; Jiang, L.; Wu, X.; Li, Y.; Qin, P.
10.1101/2022.10.17.512475 — neuroscience — Posted on 2022-10-21
1549 Macaque Brainnetome Atlas with Fine-grained Parcellations and Reliable Connections
Lu, Y.; Cui, Y.; Cao, L.; Cheng, L.; Wang, C.; Liu, Y.; Zhang, B.; Wang, H.; Li, K.; Ma, L.; Shi, W.; Li, W.; Dong, Z.; Ma, Y.; Du, Z.; Xiong, H.; Luo, N.; Liu, Y.; Hou, X.; Liu, X.; Sun, H.; Wang, J.; Paxinos, G.; Yang, Z.; Fan, L.; Jiang, T.
10.1101/2022.10.18.512488 — neuroscience — Posted on 2022-10-21
1550 Distinct beta frequencies reflect categorical decisions
Rassi, E.; Zhang, Y.; Mendoza, G.; Mendez, J. C.; Merchant, H.; Haegens, S.
10.1101/2022.10.17.512497 — neuroscience — Posted on 2022-10-21
1551 Actigraphic Correlates of Neuropsychiatric Disability in Adult Patients with Focal Epilepsy
Abboud, M. A.; Kamenn, J. L.; Bass, J. S.; Lin, L.; Gavvala, J. R.; Rao, S.; Smagula, S. F.; Krishnan, V.
10.1101/2022.10.18.512750 — neuroscience — Posted on 2022-10-21
1552 Neural Representation of The Self
Levorsen, M.; Aoki, R.; Matsumoto, K.; Sedikides, C.; Izuma, K.
10.1101/2022.10.19.512950 — neuroscience — Posted on 2022-10-21
1559 Early life sleep disruption has long lasting, sex specific effects on later development of sleep in prairie voles
Jones-Tinsley, C. E.; Olson, R. J.; Mader, M.; Wickham, P. T.; Gutowsky, K.; Wong, C.; Chu, S. S.; Milman, N. E. P.; Cao, H.; Lim, M. M.
10.1101/2022.10.18.512732 — neuroscience — Posted on 2022-10-21
1562 Sex differences in pain: Spinal cord injury in female and male mice elicits neuropathic pain symptoms
Lee, S. E.; Greenough, E. K.; Oancea, P.; Scheinfeld, A. R.; Douglas, A. M.; Gaudet, A. D.
10.1101/2022.10.18.512805 — neuroscience — Posted on 2022-10-21
1563 Menopause, Brain Anatomy, Cognition and Alzheimer's Disease
Costantino, M.; Pigeau, G.; Parent, O.; Ziolkowski, J.; Devenyi, G. A.; Gervais, N. J.; Chakravarty, M. M.
10.1101/2022.10.18.512730 — neuroscience — Posted on 2022-10-21
1565 Intra-V1 functional networks predict observed stimuli
Ontivero-Ortega, M.; Iglesias-Fuster, J.; Marinazzo, D.; Valdes-Sosa, M. J.
10.1101/2022.10.20.513108 — neuroscience — Posted on 2022-10-21
1569 Striatal dopamine synthesis and cognitive flexibility differ between hormonal contraceptive users and non-users
Taylor, C.; Furman, D.; Berry, A.; White, R. L.; Jagust, W. J.; D'Esposito, M.; Jacobs, E. G.
10.1101/2022.10.20.513082 — neuroscience — Posted on 2022-10-21
1572 Cultural determinants of the gap between self-estimated navigation ability and wayfinding performance: evidence from 46 countries.
Walkowiak, S.; Coutrot, A.; Hegarty, M.; Velasco, P. F.; Wiener, J. M.; Dalton, R. C.; Hölscher, C.; Hornberger, M.; Spiers, H. J.; Manley, E.
10.1101/2022.10.19.512889 — neuroscience — Posted on 2022-10-21
1574 Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies
Frame, A. K.; Robinson, J. W.; Mahmoudzadeh, N. H.; Tennessen, J. M.; Simon, A. F.; Cumming, R. C.
10.1101/2022.10.19.512981 — neuroscience — Posted on 2022-10-21
1580 Patterns of community science data use in peer-reviewed research on biodiversity
Binley, A. D.; Vincent, J.; Rytwinski, T.; Proctor, C.; Urness, E.; Davis, S.; Soroye, P.; Bennett, J. R.
10.1101/2022.10.17.512636 — scientific communication and education — Posted on 2022-10-21
1581 ROCK2 Knockout Improves Proliferation Rate in a Cellular Model of Down Syndrome
LeBlanc-Straceski, J.; Williams, R.; Ward, K.; Bates, A.; Duran, C.; Anderson, L.; Murray, M.; PereiraBadji, J.; Shoushani, C.; Thibault, J.
10.1101/2022.10.20.513071 — cell biology — Posted on 2022-10-21
1582 Identification of Aryl Hydrocarbon Receptor as a Barrier to HIV-1 Infection and Outgrowth in CD4+ T-Cells
Chatterjee, D.; Zhang, Y.; Wiche Salinas, T. R.; Ngassaki-Yoka, C.-D.; Chen, H.; Smail, Y.; Goulet, J.-P.; Bell, B.; Routy, J.-P.; Ancuta, P.
10.1101/2022.10.17.512596 — immunology — Posted on 2022-10-21
1583 LRBA balances antigen presentation and T-cell responses by facilitating autophagy through the binding to PIK3R4 and FYCO1
Gamez-Diaz, L.; Ligeon, L. A.; Sindram, E.; Dear, M. C.; Sanchez-Martin, P.; Nestel, S.; Jung, S.; Ruf, S.; Mishra, P.; Proietti, M.; Guenther, S.; Thedieck, K.; Roussa, E.; Rambold, A.; Muenz, C.; Kraft, C.; Grimbacher, B.
10.1101/2022.10.17.512524 — immunology — Posted on 2022-10-21
1584 Neural activity in human eyeblink conditioning: an optically pumped magnetometer-based MEG study
Lin, C.-H. S.; Tierney, T. M.; Mellor, S.; ONeill, G. C.; Bestmann, S.; Barnes, G. R.; Miall, R. C.
10.1101/2022.10.19.510727 — neuroscience — Posted on 2022-10-21
1587 Telomere-induced senescence increases aberrant intraneuronal amyloid-β accumulation by impairing autophagy in a mouse model of Alzheimer's disease
Suelves, N.; Saleki, S.; Ibrahim, T.; Palomares, D.; Vrancx, C.; Vadukul, D. M.; Papadopoulos, N.; Viceconte, N.; Claude, E.; Constantinescu, S. N.; Decottignies, A.; Kienlen-Campard, P.
10.1101/2022.10.17.512098 — neuroscience — Posted on 2022-10-21
1591 Multilocation trials identify stable high yielding spring bread and durum wheat cultivars in Mexico
Valenzuela-Antelo, J. L.; Benitez-Riquelme, I.; Vargas-Hernandez, M.; Huerta-Espino, J.; Bentley, A. R.; Villasenor-Mir, H. E.; Pinera-Chavez, F. J.
10.1101/2022.10.17.512639 — plant biology — Posted on 2022-10-21
1592 A reversible SRC-relayed COX2-inflammatory program drives therapeutic resistance in BRAF(V600E) colorectal tumors
Ruiz-Saenz, A.; Atreya, C. E.; Wang, C.; Pan, B.; Dreyer, C. A.; Brunen, D.; Prahallad, A.; Munoz, D. P.; Ramms, D. J.; Burghi, V.; Spassov, D. S.; Fewings, E.; Hwang, Y. C.; Cowdrey, C.; Moelders, C.; Schwarzer, C.; Wolf, D. M.; Hann, B.; VandenBerg, S. R.; Shokat, K.; Moasser, M. M.; Bernards, R.; Gutkind, J. S.; van't Veer, L. J.; Coppe, J.-P.
10.1101/2022.10.20.512885 — cancer biology — Posted on 2022-10-21
1594 Structure and mechanics of the human Nuclear Pore Complex basket
Vial, A.; Costa, L.; Dosset, P.; Rosso, P.; Boutieres, G.; Faklaris, O.; Haschke, H.; Milhiet, P.-E.; Doucet, C. M.
10.1101/2022.10.20.513091 — biophysics — Posted on 2022-10-21
1596 Nucleotide binding is the critical regulator of ABCG2 conformational transitions
Gyöngy, Z.; Mocsar, G.; Hegedus, E.; Stockner, T.; Ritter, Z.; Homolya, L.; Schamberger, A.; Orban, T. I.; Remenyik, J.; Szakacs, G.; Goda, K.
10.1101/2022.10.19.512890 — biochemistry — Posted on 2022-10-21
1598 EPIGENETIC LANDSCAPE OF HEAT STRESS INTERGENERATIONAL INHERITANCE IN A TELEOST FISH
Brionne, A.; Goupil, A.-S.; Kica, S.; Lareyre, J.-J.; LABBE, C.; Laurent, A.
10.1101/2022.10.17.512480 — genomics — Posted on 2022-10-21
1599 Comparative genome analysis of Enterococcus cecorum reveals intercontinental spread of a lineage of clinical poultry isolates.
Laurentie, J.; Loux, V.; Hennequet-Antier, C.; Chambellon, E.; Deschamps, J.; Trotereau, A.; Furlan, S.; Darrigo, C.; Kempf, F.; Lao, J.; Milhes, M.; Lopez-Roques, C.; Quinquis, B.; Vandecasteele, C.; Boyer, R.; Bouchez, O.; Repoila, F.; Le Guennec, J.; Chiapello, H.; Briandet, R.; Helloin, E.; Schouler, C.; Kempf, I.; Serror, P.
10.1101/2022.10.18.512807 — genomics — Posted on 2022-10-21
1601 Antimicrobial resistance of Enterococcus cecorum: ECOFF determination
Laurentie, J.; Mourand, G.; Grippon, P.; Furlan, S.; Chauvin, C.; Jouy, E.; Serror, P.; Kempf, I.
10.1101/2022.10.19.512977 — microbiology — Posted on 2022-10-21
1602 Chronic IFNα treatment induces leukopoiesis, increased plasma succinate and immune cell metabolic rewiring
Leisching, G.; Yennemadi, A.; Keane, J.; De Pasquale, C.; Bianchi, M.; Glass, M.; Jameson, G.
10.1101/2022.10.17.512487 — immunology — Posted on 2022-10-21
1603 Enhanced donor antigen presentation by B-cells predicts acute cellular rejection and late outcomes after transplantation.
Ashokkumar, C.; Ningappa, M.; Raghu, V.; Mazariegos, G.; Higgs, B. W.; Morgan, P.; Remaley, L.; Fazzolare, T.; Holzer, P.; Trostle, K.; Xu, Q.; Zeevi, A.; Squires, J.; Soltys, K.; Horslen, S.; Khanna, A.; Ganoza,, A.; Sindhi, R.
10.1101/2022.10.17.511155 — immunology — Posted on 2022-10-21
1604 Overexpression of Interleukin-8 and Interleukin-13 as potent immune markers associated with survival and dietary habits in esophageal squamous cell carcinoma.
Talukdar, J.; Malik, A.; Kataki, K.; Choudhury, B. N.; Baruah, M. N.; Bhattacharyya, M.; Alkholief, M.; Alshamsan, A.; Sarma, M. P.; Bhattacharjee, M.; Basak, M.; Kashyap, M. P.; Bhattacharjee, S.; Ali, E.; Keppen, C.; Idris, M. G.; Medhi, S.
10.1101/2022.10.17.512528 — immunology — Posted on 2022-10-21
1605 Specific and non-uniform brain states during cold perception in mice
Koorliyil, H.; Sitt, J.; Rivals, I.; Liu, Y.; Cazzanelli, S.; Bertolo, A.; Dizeux, A.; Deffieux, T.; Tanter, M.; Pezet, S.
10.1101/2022.10.20.513008 — neuroscience — Posted on 2022-10-21
1606 A cautionary note on quantitative measures of phenotypic convergence
Grossnickle, D. M.; Brightly, W. H.; Weaver, L. N.; Stanchak, K. E.; Roston, R. A.; Pevsner, S. K.; Stayton, C. T.; Polly, P. D.; Law, C. J.
10.1101/2022.10.18.512739 — evolutionary biology — Posted on 2022-10-21
1607 Extreme mito-nuclear discordance within Anthozoa, with notes on unique properties of their mitochondrial genomes
Quattrini, A. M.; Snyder, K.; Purow-Ruderman, R.; Seiblitz, I. G. L.; Hoang, J.; Floerke, N.; Ramos, N. I.; Wirshing, H. H.; Rodriguez, E.; McFadden, C. S.
10.1101/2022.10.18.512751 — evolutionary biology — Posted on 2022-10-21
1609 Myelination and excitation-inhibition balance synergistically shape structure-function coupling across the human cortex
Fotiadis, P.; Cieslak, M.; He, X.; Caciagli, L.; Ouellet, M.; Satterthwaite, T. D.; Shinohara, R. T.; Bassett, D. S.
10.1101/2022.10.20.512802 — neuroscience — Posted on 2022-10-21
1612 Environmental gradients reveal stress hubs predating plant terrestrialization
Dadras, A.; Fuerst-Jansen, J. M.; Darienko, T.; Krone, D.; Scholz, P.; Rieseberg, T. P.; Irisarri, I.; Steinkamp, R.; Hansen, M.; Buschmann, H.; Valerius, O.; Braus, G. H.; Hoecker, U.; Mutwil, M.; Ischebeck, T.; de Vries, S.; Lorenz, M.; de Vries, J.
10.1101/2022.10.17.512551 — evolutionary biology — Posted on 2022-10-21
1613 Elasmobranch genome sequencing reveals evolutionary trends of vertebrate karyotypic organization
Yamaguchi, K.; Uno, Y.; Kadota, M.; Nishimura, O.; Murakumo, K.; Nozu, R.; Matsumoto, R.; Sato, K.; Kuraku, S.
10.1101/2022.10.17.512540 — evolutionary biology — Posted on 2022-10-21
1615 Dietary restriction fails to extend life in stressful environments
Zajitschek, F.; Zajitschek, S. R. K.; Vasconcelos, A. C. O.; Bonduriansky, R.
10.1101/2022.10.17.512576 — evolutionary biology — Posted on 2022-10-21
1616 Kinship and genetic variation in aquarium-spawned Acropora hyacinthus corals
Lopez-Nandam, E. H.; Payne, C. Y.; Delbeek, J. C.; Dunker, F.; Krol, L.; Larkin, L.; Lev, K.; Ross, R.; Schaeffer, R.; Yong, S.; Albright, R.
10.1101/2022.10.18.512587 — evolutionary biology — Posted on 2022-10-21
1623 Multi-scale phenological niches of seed fall in diverse Amazonian plant communities
Pak, D.; Swamy, V.; Alvarez-Loayza, P.; Cornejo, F.; Queenborough, S. A.; Metz, M. R.; Terborgh, J.; Valencia, R.; Wright, S. J.; Garwood, N. C.; Lasky, J. R.
10.1101/2021.04.10.438715 — ecology — Posted on 2022-10-21
1625 The Opto-inflammasome in zebrafish: a tool to study cell and tissue responses to speck formation and cell death
Hasel de Carvalho, E.; Dharmadhikari, S.; Shkarina, K.; Xiong, J. R.; Reversade, B.; Broz, P.; Leptin, M.
10.1101/2022.10.19.512883 — immunology — Posted on 2022-10-21
1628 Control of contextual memory through interneuronal α5-GABAA receptors
Zhu, M.; Abdulzahir, A.; Perkins, M.; Chu, C. C.; Krause, B.; Casey, C.; Lennertz, R.; Ruhl, D.; Hentschke, H.; Nagarajan, R.; Chapman, E. R.; Rudolph, U.; Fanselow, M.; Pearce, R.
10.1101/2022.03.03.482912 — neuroscience — Posted on 2022-10-21
1630 Atypical Child-Parent Neural Synchrony Links to Children's Psychopathological Symptoms
Su, H.; Young, C. B.; Han, Z. R.; Xu, J.; Xiong, B.; Wang, J.; Hao, L.; Yang, Z.; Chen, G.; Qin, S.
10.1101/2022.03.30.486310 — neuroscience — Posted on 2022-10-21
1632 Distinct hyperactive RAS/MAPK alleles converge on common GABAergic interneuron core programs
Knowles, S. J.; Stafford, A. M.; Zaman, T.; Angara, K.; Williams, M. R.; Newbern, J. M.; Vogt, D.
10.1101/2022.08.04.502867 — neuroscience — Posted on 2022-10-21
1634 Structural and Dynamic Insights Into α-Synuclein Dimer Conformations
Zamel, J.; Chen, J.; Zaer, S.; Harris, P. D.; Drori, P.; Lebendiker, M.; Kalisman, N.; Dokholyan, N. V.; Lerner, E.
10.1101/795997 — biophysics — Posted on 2022-10-21
1635 A benchmark study of protein folding algorithms on nanobodies
Liang, S.; Liang, Z.; Wu, Z.; Huang, F.; Wang, X.; Tan, Z.; He, R.; Lu, Z.; Cai, Y.; Huang, B.; Wang, X.
10.1101/2022.08.07.503071 — bioinformatics — Posted on 2022-10-21
1638 Canary in the cardiac-valve coal mine: Flow velocity and inferred shear during prosthetic valve closure -predictors of blood damage and clotting
Scotten, L. N.; Siegel, R.; Blundon, D. J.; Deutsch, M.-A.; Martin, T. R. P.; Dutton, J. W.; Kolahdouz, E. M.; Griffith, B. E.
10.1101/2022.06.23.497372 — bioengineering — Posted on 2022-10-21
1643 Characterization of novel Actinobacteriophage Giantsbane reveals unexpected cluster AU relationships
Chen, P. Y.; Liu, C.; Dang, P.; Zhang, M.; Kapinos, A.; Ngo, R. T.; Moberg Parker, J.; Freise, A. C.
10.1101/2020.01.10.891226 — genomics — Posted on 2022-10-21
1644 The human inactive X chromosome modulates expression of the active X chromosome
San Roman, A. K.; Godfrey, A. K.; Skaletsky, H.; Bellott, D. W.; Groff, A. F.; Harris, H. L.; Blanton, L. V.; Hughes, J. F.; Brown, L.; Phou, S.; Buscetta, A.; Kruszka, P.; Banks, N.; Dutra, A.; Pak, E.; Lasutschinkow, P. C.; Keen, C.; Davis, S. M.; Tartaglia, N. R.; Samango-Sprouse, C.; Muenke, M.; Page, D. C.
10.1101/2021.08.09.455676 — genetics — Posted on 2022-10-21
1645 Genome-Wide Association Study in a Rat Model of Temperament Identifies Multiple Loci for Exploratory Locomotion and Anxiety-Like Traits
Chitre, A. S.; Hebda-Bauer, E. K.; Blandino, P.; Bimschleger, H.; Nguyen, K.-M.; Maras, P.; Li, F.; Ozel, A. B.; Polesskaya, O.; Cheng, R.; Flagel, S. B.; Watson, S. J.; Li, J.; Akil, H.; Palmer, A. A.
10.1101/2022.07.12.499605 — genetics — Posted on 2022-10-21
1648 Genetic architectures of postmating isolation and morphology of two highly diverged rockfishes (genus Sebastes)
Muto, N.; Kawasaki, T.; Kakioka, R.; Nagano, A. J.; Shimizu, Y.; Inose, S.; Shimizu, Y.; Takahashi, H.
10.1101/2022.05.27.493803 — evolutionary biology — Posted on 2022-10-21
1649 Coral assemblages at higher latitudes favour short-term potential over long-term performance
Cant, J.; Reimer, J. D.; Sommer, B.; Cook, K.; Kim, S. W.; Sims, C. A.; Mezaki, T.; O'Flaherty, C.; Brooks, M.; Malcolm, H. A.; Pandolfi, J. M.; Salguero-Gomez, R.; Beger, M.
10.1101/2021.09.29.462350 — ecology — Posted on 2022-10-21
1650 High overexploitation risk due to management shortfall in highly traded requiem sharks
Sherman, C. S.; Digel, E. D.; Zubick, P.; Eged, J.; Haque, A. B.; Matsushiba, J. H.; Simpfendorfer, C. A.; Sant, G.; Dulvy, N. K.
10.1101/2022.06.09.495558 — ecology — Posted on 2022-10-21
1651 Stingless bee floral visitation in the global tropics and subtropics
Garcia Bulle Bueno, F.; Kendall, L.; de Araujo Alves, D.; Lequerica Tamara, M.; Heard, T. A.; Latty, T.; Gloag, R.
10.1101/2021.04.26.440550 — ecology — Posted on 2022-10-21
1654 Persistent acetylation of histone H3 lysine 56 compromises the activity of DNA replication origins
Tremblay, R.; Merhjoo, Y.; Simoneau, A.; McQuaid, M.; Nislow, C.; Giaever, G.; Wurtele, H.
10.1101/2022.03.22.485257 — molecular biology — Posted on 2022-10-21
1655 Intestinal lamina propria supports acquired eTreg suppressor function
Gu, Y.; Bartolome-Casado, R.; Xu, C.; Janney, A.; Heuberger, C.; Pearson, C.; Teichmann, S.; Thornton, E. E.; Powrie, F.
10.1101/2022.08.26.505428 — immunology — Posted on 2022-10-21
1657 Ciliary neurotrophic factor-mediated neuroprotection involves enhanced glycolysis and anabolism in degenerating mouse retinas
Rhee, K. D.; Wang, Y.; Hoeve, J. t.; Stiles, L.; Nguyen, T. T. T.; Zhang, X.; Vergnes, L.; Reue, K.; Shirihai, O. S.; Bok, D.; Yang, X.-J.
10.1101/2021.12.21.473752 — neuroscience — Posted on 2022-10-21
1659 A retroviral origin of vertebrate myelin
Ghosh, T.; Almeida, R. G.; Zhao, C.; Mannioui, A.; Martin, E.; Fleet, A.; Gonzalez M, G.; Rowitch, D. H.; Stott, K.; Adams, I.; Zalc, B.; Goldman, N.; Lyons, D. A.; Franklin, R. J.
10.1101/2022.01.24.477350 — neuroscience — Posted on 2022-10-21
1660 Reconstructing the functional effect of TP53 somatic mutations on its regulon using causal signalling network modelling
Triantafyllidis, C.; Barberis, A.; Miar, A.; Chartlon, P.; Hartley, F.; Van Bijsterveldt, L.; Gjerga, E.; Saez-Rodriguez, J.; Buffa, F. M.
10.1101/2022.06.23.497293 — systems biology — Posted on 2022-10-21
1662 An integrated view of baseline protein expression in human tissues
Prakash, A.; Garcia-Seisdedos, D.; Wang, S.; Kundu, D. J.; Collins, A.; George, N.; Moreno, P.; Papatheodorou, I.; Jones, A. R.; Vizcaino, J. A.
10.1101/2021.09.10.459811 — bioinformatics — Posted on 2022-10-21
1663 Mera: A scalable high throughput automated micro-physiological system
Cliffe, F.; Costello, P.; Madden, C.; Devitt, S.; Mukkunda, S. R.; Keshava, B. B.; Fearnhead, H.; Vitkuaskaite, A.; Dehkordi, M.; Chingwaru, W.; Przyjalgowski, M.; Rebrova, N.; Lyons, M.
10.1101/2022.08.30.505827 — bioengineering — Posted on 2022-10-21
1664 Integrative modeling reveals the molecular architecture of the Intraflagellar Transport A (IFT-A) complex
McCafferty, C. L.; Papoulas, O.; Jordan, M. A.; Hoogerbrugge, G.; Nichols, C.; Pigino, G.; Taylor, D. W.; Wallingford, J. B.; Marcotte, E. M.
10.1101/2022.07.05.498886 — biochemistry — Posted on 2022-10-21
1665 Beyond consensus sequence: a quantitative scheme for inferring transmission using deep sequencing in a bacterial transmission model
Senghore, M.; Read, H. M.; Oza, P.; Johnson, S.; Passarelli-Araujo, H.; Taylor, B. P.; Ashley, S.; Grey, A. B.; Callendrello, A.; Lee, R. S.; Goddard, M. R.; Lumley, T.; Hanage, W. P.; Wiles, S.
10.1101/2022.10.17.512634 — genomics — Posted on 2022-10-20
1667 SARS-CoV-2 infected cells sprout actin-rich filopodia that facilitate viral invasion
Jiu, Y.; Zhang, Y.; Zhang, X.; Li, Z.; Yang, H.; Tang, D.; Zhao, S.; Zhang, Q.; Li, B.; Lappalainen, P.; Cui, Z.; Liu, H.; Li, H.; Zhao, W.
10.1101/2022.10.19.512957 — cell biology — Posted on 2022-10-20
1668 Genome sequencing of the Monkeypox virus 2022 outbreak with Amplicon-based Oxford Nanopore MinION sequencing
Brinkmann, A.; Pape, K.; Uddin, S.; Woelk, N.; Foerster, S.; Jessen, H.; Michel, J.; Kohl, C.; Schaade, L.; Nitsche, A.
10.1101/2022.10.20.512862 — molecular biology — Posted on 2022-10-20
1669 Structure of human TRPM8 channel.
Palchevskyi, S.; Czarnocki-Cieciura, M.; Vistoli, G.; Gervasoni, S.; Nowak, E.; Beccari, A. R.; Nowotny, M.; Talarico, C.
10.1101/2022.10.19.512915 — molecular biology — Posted on 2022-10-20
1670 Complex regulation of gamma-hemolysin expression impacts S. aureus virulence
Pivard, M.; Caldelari, I.; Brun, V.; Croisier, D.; Jaquinod, M.; Anzala, N.; Gilquin, B.; Teixeira, C.; Benito, Y.; Couzon, F.; Romby, P.; Moreau, K.; Vandenesch, F.
10.1101/2022.10.19.512982 — microbiology — Posted on 2022-10-20
1673 Altered infective competence of the human gut microbiome in COVID-19
de Nies, L.; Galata, V.; Martin-Gallausiaux, C.; Despotovic, M.; Busi, S. B.; Snoeck, C. J.; Delacour, L.; Budagavi, D. P.; Laczny, C. C.; Habier, J.; Lupu, P.-C.; Halder, R.; Fritz, J. V.; Marques, T.; Sandt, E.; O'Sullivan, M. P.; Ghosh, S.; Satagopam, V.; CON-VINCE Consortium, ; Kruger, R.; Fagherazzi, G.; Ollert, M.; Hefeng, F. Q.; May, P.; Wilmes, P.
10.1101/2022.10.20.512999 — microbiology — Posted on 2022-10-20
1674 High-throughput transposon mutagenesis in the family Enterobacteriaceae reveals core essential genes and rapid turnover of essentiality
Ashari Ghomi, F.; Langridge, G.; Cain, A. K.; Boinett, C. J.; Abd El Ghany, M.; Pickard, D. J.; Kingsley, R. A.; Thomson, N.; Parkhill, J.; Gardner, P. P.; Barquist, L.
10.1101/2022.10.20.512852 — microbiology — Posted on 2022-10-20
1675 Forecasting of a complex microbial community using meta-omics
Delogu, F.; Kunath, B. J.; Queiros, P.; Halder, R.; Lebrun, L. A.; Pope, P. B.; May, P.; Widder, S.; Muller, E. E. L.; Wilmes, P.
10.1101/2022.10.19.512887 — microbiology — Posted on 2022-10-20
1676 Distinct Neutralizing Antibody Escape of SARS-CoV-2 Omicron Subvariants BQ.1, BQ.1.1, BA.4.6, BF.7 and BA.2.75.2
Qu, P.; Evans, J. P.; Faraone, J.; Zheng, Y.-M.; Carlin, C.; Anghelina, M.; Stevens, P.; Fernandez, S.; Jones, D.; Lozanski, G.; Panchal, A.; Saif, L. J.; Oltz, E. M.; Xu, K.; Gumina, R. J.; Liu, S.-L.
10.1101/2022.10.19.512891 — microbiology — Posted on 2022-10-20
1677 Ancestral SARS-CoV-2 driven antibody repertoire diversity in an unvaccinated individual correlates with expanded neutralization breadth
Deshpande, S.; Ansari, M. Y.; Sutar, J.; Das, P.; Hingankar, N.; Mukherjee, S.; Jayal, P.; Singh, S.; Anantharaj, A.; Singh, J.; Chattopadhyay, S.; Raghavan, S.; Gosain, M.; Chauhan, S.; Shrivas, S.; Prasad, C.; Chauhan, S.; Sharma, N.; Jana, P.; Thiruvengadam, R.; Kshetrapal, P.; Wadhwa, N.; Das, B.; Batra, G.; Medigeshi, G. R.; Sok, D.; Bhatnagar, S.; Garg, P.; Bhattacharya, J.
10.1101/2022.10.19.512979 — immunology — Posted on 2022-10-20
1678 Engineered synthetic one-carbon fixation exceeds yield of the Calvin Cycle
Dronsella, B. B.; Orsi, E.; Benito-Vaquerizo, S.; Glatter, T.; Bar-Even, A.; Erb, T. J.; Claassens, N. J.
10.1101/2022.10.19.512895 — synthetic biology — Posted on 2022-10-20
1679 Loss of Linker Histone H1 in the Maternal Genome Influences DEMETER-Mediated Demethylation and Affects the Endosperm DNA Methylation Landscape
Hsieh, T.-F.; Han, Q.; Hung, Y.-H.; Zhang, C.; Bartels, A.; Rea, M.; Yang, H.; Park, C.; Zhang, X.-Q.; Fsicher, R. L.; Xiao, W.
10.1101/2022.10.17.512625 — plant biology — Posted on 2022-10-20
1686 Spatial Transcriptomics of Intraductal Papillary Mucinous Neoplasms of The Pancreas Identifies NKX6-2 Expression as a Driver of Gastric Differentiation and Indolent Biological Potential
Sans, M.; Makino, Y.; Min, J.; Rajapakshe, K. I.; Yip-Schneider, M.; Schmidt, C. M.; Hurd, M. W.; Burks, J. K.; Gomez, J. A.; Thege, F. I.; Fahrmann, J.; Wolff, R. A.; Kim, M. P.; Guerrero, P. A.; Maitra, A.
10.1101/2022.10.19.512773 — cancer biology — Posted on 2022-10-20
1687 A histone methylation-MAPK signaling axis drives durable epithelial-mesenchymal transition in hypoxic pancreas cancer
Brown, B. A.; Myers, P. J.; Adair, S. J.; Pitarresi, J. R.; Sah-Teli, S. K.; Hart, W. S.; Barbeau, M.; Leong, K.; Seyler, N.; Kane, W.; Lee, K. E.; Stelow, E.; Simon, M. C.; Koivunen, P.; Bauer, T. W.; Stanger, B. Z.; Lazzara, M. J.
10.1101/2022.10.19.512869 — cancer biology — Posted on 2022-10-20
1688 SARS-CoV2 E and 3a proteins are inducers of pannexin currents
Oliveira Mendes, B.; Alameh, M.; Ollivier, B.; Montnach, J.; Bidere, N.; Souaze, F.; Escriou, N.; Charpentier, F.; Baro, I.; De Waard, M.; Loussouarn, G.
10.1101/2022.10.20.513002 — cell biology — Posted on 2022-10-20
1690 Staphylococcus aureus SigS induces expression of a regulatory protein pair that modulate its mRNA stability
Al Ali, A.; Alsulami, J.; Aubee, J. I.; Idowu, A.; Tomlinson, B.; Felton, E. A.; Jackson, J.; Shaw, L. N.; Thompson, K. M.
10.1101/2022.10.19.512975 — microbiology — Posted on 2022-10-20
1694 Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients
Rouet, R.; Henry, J. Y.; Johansen, M. D.; Sobti, M.; Balachandran, H.; Langley, D. B.; Walker, G.; Lenthall, H.; Jackson, J.; Ubiparipovic, S.; Mazigi, O.; Schofield, P.; Burnett, D. L.; Brown, S. H. J.; Martinello, M.; Hudson, B.; Gilroy, N.; Post, J. J.; Kelleher, A.; Jäck, H.-M.; Goodnow, C.; Turville, S. G.; Rawlinson, W. D.; Bull, R. A.; Stewart, A. G.; Hansbro, P. M.; Christ, D.
10.1101/2022.10.19.512954 — immunology — Posted on 2022-10-20
1695 Molecular basis of FAAH-OUT-associated human pain insensitivity
Mikaeili, H.; Habib, A. M.; Yeung, C.; Santana-Varela, S.; Luiz, A. P.; Panteleeva, K.; Zuberi, S.; Athanasiou-Fragkouli, A.; Houlden, H.; Wood, J. N.; Okorokov, A. L.; Cox, J. J.
10.1101/2022.10.20.513066 — neuroscience — Posted on 2022-10-20
1696 A Deep-learning based RNA-seq Germline Variant Caller
Cook, D. E.; Venkat, A.; Yelizarov, D.; Pouliot, Y.; Chang, P.-C.; Carroll, A.; De La Vega, F. M.
10.1101/2022.10.16.512451 — bioinformatics — Posted on 2022-10-20
1699 aRgus: multilevel visualization of non-synonymous single nucleotide variants & advanced pathogenicity score modeling for genetic vulnerability assessment
Schroeter, J.; Dattner, T.; Huellein, J.; Jayme, A.; Heuveline, V.; Hoffmann, G. F.; Koelker, S.; Lenz, D.; Opladen, T.; Popp, B.; Schaaf, C. P.; Staufner, C.; Syrbe, S.; Uhrig, S.; Huebschmann, D.; Brennenstuhl, H.
10.1101/2022.10.20.513018 — bioinformatics — Posted on 2022-10-20
1701 Intra-host viral populations of SARS-CoV-2 in immunosuppressed patients with hematologic cancers
Fournelle, D.; Mostefai, F.; Brunet-Ratnasingham, E.; Poujol, R.; Grenier, J.-C.; Galvez, J. H.; Pagliuzza, A.; Levade, I.; Moreira, S.; Grandjean Lapierre, S.; Chomont, N.; Kaufmann, D. E.; Craig, M.; Hussin, J.
10.1101/2022.10.19.512884 — genomics — Posted on 2022-10-20
1704 Microscopic Imaging of Epigenetic Age
Rodriguez, D.; Fiengo, L.; Alvarez-Kuglen, M.; Qin, H.; Farhy, C.; Havas, A.; Anderson, R. M.; Adams, P. D.; Sharpee, T. O.; Terskikh, A.
10.1101/2022.10.16.512441 — systems biology — Posted on 2022-10-20
1706 Modifications in the piperazine ring of nucleozin affects anti-influenza activity
Correa-Padilla, E.; Hernandez-Cano, A.; Cuevas, G.; Acevedo-Betancur, Y.; Esquivel-Guadarrama, F.; Madariaga-Mazon, A.; Martinez-Mayorga, K.
10.1101/2022.10.20.513012 — pharmacology and toxicology — Posted on 2022-10-20
1707 Improved KCNQ2 gene missense variant interpretation with artificial intelligence
Saez-Matia, A.; Muguruza-Montero, A.; M-Alicante, S.; Nunez, E.; Gamis, R.; Ballesteros, O. R.; Garcia-Ibarlueza, M.; Fons, C.; Leonardo, A.; Bergara, A.; Villarroel, A.
10.1101/2022.10.20.513007 — pathology — Posted on 2022-10-20
1711 A microfluidic finger-actuated blood lysate preparation device enabled by rapid acoustofluidic mixing
Haque, M. E.; Conde, A. J.; MacPherson, W. N.; Knight, S. R.; Carter, R.; KERSAUDY-KERHOAS, M.
10.1101/2022.10.16.512425 — bioengineering — Posted on 2022-10-20
1713 Patterning of phase-separated condensates by Dnd1 controls cell fate
Westerich, K. J.; Tarbashevich, K.; Gupta, A.; Zhu, M.; Hull, K.; Romo, D.; Gross-Thebing, T.; Raz, E.
10.1101/2022.10.20.512863 — cell biology — Posted on 2022-10-20
1715 Automated neuronal reconstruction with super-multicolour fluorescence imaging
Leiwe, M. N.; Fujimoto, S.; Baba, T.; Moriyasu, D.; Sakaguchi, R.; Saha, B.; Inagaki, S.; Imai, T.
10.1101/2022.10.20.512984 — neuroscience — Posted on 2022-10-20
1718 High performance genetically-encoded green fluorescent biosensors for intracellular L-lactate
Le, G. N. T.; Hario, S.; Takahashi-Yamashiro, K.; Li, S.; Drobizhev, M.; Nasu, Y.; Campbell, R. E.
10.1101/2022.10.19.512892 — bioengineering — Posted on 2022-10-20
1719 3D genome topologies distinguish pluripotent epiblast and primitive endoderm cells in the mouse blastocyst
Loof, G.; Szabo, D.; Garg, V.; Kukalev, A.; Zea-Redondo, L.; Kempfer, R.; Sparks, T. M.; Zhang, Y.; Thieme, C. J.; Carvalho, S.; Weise, A.; Balachandran, M.; Liehr, T.; Welch, L. R.; Hadjantonakis, A.-K.; Pombo, A.
10.1101/2022.10.19.512781 — developmental biology — Posted on 2022-10-20
1720 Sequencing and chromosome-scale assembly of the giant Pleurodeles waltl genome
Brown, T.; Elewa, A.; Iarovenko, S.; Subramanian, E.; Joven Araus, A.; Petzold, A.; Suzuki, M.; Suzuki, K.-i.; Hayashi, T.; Toyoda, A.; Oliveira, C.; Osipova, E.; Leigh, N.; Simon, A.; Yun, M.
10.1101/2022.10.19.512763 — developmental biology — Posted on 2022-10-20
1721 Noncanonical CDK4 signaling rescues diabetes in a mouse model by promoting beta cell differentiation
Stamateris, R. E.; Sharma, R. B.; Landa-Galvan, H. V.; Darko, C.; Redmond, D.; Rane, S. G.; Alonso, L. C.
10.1101/2022.10.19.512511 — cell biology — Posted on 2022-10-20
1724 Agonistic anti-CD40 converts Tregs into Type 1 effectors within the tumor micro-environment
Maltez, V.; Arora, C.; Sor, R.; Lian, Q.; Vonderheide, R. H.; Germain, R. N.; Byrne, K. T.
10.1101/2022.10.17.512537 — immunology — Posted on 2022-10-20
1725 SGC-CAMKK2-1: A chemical probe for CAMKK2
Wells, C. I.; Liang, Y.; Pulliam, T. L.; Lin, C.; Awad, D.; Eduful, B.; O Byrne, S.; Hossain, M. A.; Catta-Preta, C.; Zonzini Ramos, P.; Gileadi, O.; Gileadi, C.; Counago, R. M.; Stork, B.; Langendorf, C. G.; Nay, K.; Oakhill, J. S.; Mukherjee, D.; Racioppi, L.; Means, A.; York, B.; McDonnell, D. P.; Scott, J. W.; Frigo, D. E.; Drewry, D. H.
10.1101/2022.10.18.512752 — cancer biology — Posted on 2022-10-20
1728 SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells
Pothast, C. R.; Dijkland, R. C.; Thaler, M.; Hagedoorn, R. S.; Kester, M. G.; Wouters, A. K.; Hiemstra, P. S.; van Hemert, M. J.; Gras, S.; Falkenburg, J. F.; Heemskerk, M. H.
10.1101/2022.07.31.502203 — immunology — Posted on 2022-10-20
1730 Genomic accordions may hold the key to Monkeypox Clade IIb's increased transmissibility
Monzon, S.; Varona, S.; Negredo, A.; Patino-Galindo, J. A.; Vidal-Freire, S.; Zaballos, A.; Orviz, E.; Ayerdi, O.; Munoz-Garcia, A.; Delgado-Iribarren, A.; Estrada, V.; Garcia, C.; Molero, F.; Sanchez, P.; Torres, M.; Vazquez, A.; Galan, J.-C.; Torres, I.; Causse del Rio, M.; Merino, L.; Lopez, M.; Galar, A.; Cardenoso, L.; Gutierrez, A.; Camacho, J.; Herrero, L.; Jimenez-Sancho, P.; Navarro-Rico, M. L.; Jado, I.; Kuhn, J.; Sanchez-Lockhart, M.; Di Paola, N.; Kugelman, J. R.; Giannetti, E.; Guerra, S.; Garcia-Sastre, A.; Palacios, G.; Cuesta, I.; Sanchez-Seco, M.
10.1101/2022.09.30.510261 — genomics — Posted on 2022-10-20
1732 A collaborative approach to improving representation in viral genomic surveillance
Kim, P.; Kim, A. Y.; Newman, J. J.; Cella, E.; Bishop, T. C.; Huwe, P. J.; Uchakina, O. N.; McKallip, R. J.; Mack, V. L.; Hill, M. P.; Ogungbe, I. V.; Adeyinka, O.; Jones, S.; Ware, G.; Carroll, J. L.; Sawyer, J. F.; Densmore, K. H.; Foster, M.; Valmond, L.; Thomas, J.; Azarian, T.; Queen, K.; Kamil, J. P.
10.1101/2022.10.19.512816 — microbiology — Posted on 2022-10-20
1734 A microtubule associated protein is essential for malaria parasite transmission
Wichers-Misterek, J. S.; Binder, A. M.; Mesen-Ramirez, P.; Dorner, L. P.; Safavi, S.; Fuchs, G.; Lenz, T. L.; Bachmann, A.; Wilson, D. W.; Frischknecht, F.; Gilberger, T.
10.1101/2022.10.18.512810 — molecular biology — Posted on 2022-10-20
1736 Polymerization cycle of actin homolog MreB from a Gram-positive bacterium
Carballido-Lopez, R.; Chastanet, A.; Mao, W.; Renner, L. D.; Cornilleau, C.; Li de la Sierra-Gallay, I.; Benlamara, S.; Ah-Seng, Y.; Van Tilbeurgh, H.; Nessler, S.; Bertin, A.
10.1101/2022.10.19.512861 — biochemistry — Posted on 2022-10-20
1738 Did variants in inborn errors of immunity genes contribute to the extinction of Neanderthals?
Zhou, Z.; Swagemakers, S. M. A.; Lourens, M. S.; Suratannon, N.; van der Spek, P.; Dalm, V. A. S. H.; Dik, W. A.; IJspeert, H.; van Hagen, P. M.
10.1101/2022.10.19.512108 — evolutionary biology — Posted on 2022-10-20
1740 Annotating and prioritizing human non-coding variants with RegulomeDB
Dong, S.; Zhao, N.; Spragins, E.; Kagda, M. S.; Li, M.; Assis, P. R.; Jolanki, O.; Luo, Y.; Cherry, J. M.; Boyle, A. P.; Hitz, B. C.
10.1101/2022.10.18.512627 — bioinformatics — Posted on 2022-10-20
1741 BMP signaling: A significant player and therapeutic target for osteoarthritis
Jaswal, A. P.; Kumar, B.; Roelofs, A. J.; Iqbal, S. F.; Singh, A. K.; Riemen, A. H. K.; Wang, H.; Sadaf, A.; Nanasaheb, S. V.; Agnihotri, N.; De Bari, C.; Bandyopadhyay, A.
10.1101/2021.03.01.433366 — pathology — Posted on 2022-10-20
1742 RNAs undergo phase transitions with lower critical solution temperatures
Wadsworth, G. M.; Zahurancik, W. J.; Zeng, X.; Pullara, P.; Lai, L. B.; Sidharthan, V.; Pappu, R. V.; Gopalan, V.; Banerjee, P. R.
10.1101/2022.10.17.512593 — biophysics — Posted on 2022-10-19
1743 Sequence-structure-function relationships in the microbial protein universe
Koehler Leman, J.; Szczerbiak, P.; Renfrew, P. D.; Gligorijevic, V.; Berenberg, D.; Vatanen, T.; Taylor, B. C.; Chandler, C.; Janssen, S.; Carriero, N.; Fisk, I.; Xavier, R. J.; Knight, R.; Bonneau, R.; Kosciolek, T.
10.1101/2022.03.18.484903 — bioinformatics — Posted on 2022-10-19
1746 A Leaky Human Colon Model Reveals Uncoupled Apical/Basal Cytotoxicity in Early Clostridioides difficile Toxin Exposure
Ok, M. T.; Liu, J.; Bliton, R. J.; Hinesley, C. M.; San Pedro, E. E. T.; Breau, K. A.; Gomez-Martinez, I.; Burclaff, J.; Magness, S. T.
10.1101/2022.10.13.511617 — cell biology — Posted on 2022-10-19
1747 Epithelial Plasticity and Innate Immune Activation Promote Lung Tissue Remodeling following Respiratory Viral Infection.
Beppu, A.; Zhao, J.; Yao, C.; Carraro, G.; Israely, E.; Coelho, A. L.; Hogaboam, C. M.; Parks, W. C.; Kolls, J. K.; Stripp, B. R.
10.1101/2021.09.22.461381 — cell biology — Posted on 2022-10-19
1748 Arginine methylation sites on SepIVA help balance elongation and septation of the cell wall in Mycobacterium smegmatis
Freeman, A. M.; Tembiwa, K.; Brenner, J. R.; Chase, M. R.; Fortune, S. M.; Morita, Y. S.; Boutte, C.
10.1101/2021.10.06.463415 — microbiology — Posted on 2022-10-19
1749 The molecular mechanism and physiological role of silent nociceptor activation
Nees, T. A.; Wang, N.; Adamek, P.; Verkest, C.; LaPorta, C.; Schaefer, I.; Virnich, J.; Balkaya, S.; Prato, V.; Morelli, C.; Zeitzschel, N.; Begay, V.; Lee, Y. J.; Tappe-Theodor, A.; Lewin, G. R.; Heppenstall, P. A.; Taberner, F. J.; Lechner, S. G.
10.1101/2022.04.07.486730 — neuroscience — Posted on 2022-10-19
1750 Functional MRS studies of GABA and Glutamate/Glx: a systematic review and meta-analysis
Pasanta, D.; He, J. L.; Ford, T. C.; Oeltzschner, G.; Lythgoe, D.; Puts, N. A.
10.1101/2022.09.07.506899 — neuroscience — Posted on 2022-10-19
1754 Evolutionary consequences of nascent multicellular life cycles
Pentz, J. T.; MacGillivray, K.; DuBose, J. G.; Conlin, P. L.; Reinhardt, E.; Libby, E.; Ratcliff, W. C.
10.1101/2022.07.21.500805 — evolutionary biology — Posted on 2022-10-19
1757 Reflective multi-immersion microscope objectives inspired by the Schmidt telescope
Voigt, F.; Reuss, A. M.; Naert, T.; Hildebrand, S.; Schaettin, M.; Hotz, A. L.; Whitehead, L.; Bahl, A.; Neuhauss, S. C. F.; Roebroeck, A.; Stoeckli, E. T.; Lienkamp, S. S.; Aguzzi, A.; Helmchen, F.
10.1101/2022.10.13.511906 — neuroscience — Posted on 2022-10-19
1760 Redox protein Memo1 coordinates FGF23-driven signaling and small Rho-GTPases in the mouse kidney
Bartos, K.; Ramakrishnan, S. K.; Braga-Lagache, S.; Haenzi, B.; Durussel, F.; Prakash Sridharan, A.; Zhu, Y.; Sheehan, D.; Hynes, N. E.; Bonny, O.; Moor, M. B.
10.1101/2020.12.04.402511 — biochemistry — Posted on 2022-10-19
1761 Resource-aware construct design in mammalian cells
Di Blasi, R.; Pisani, M.; Tedeschi, F.; Marbiah, M.; Polizzi, K. M.; Furini, S.; Siciliano, V.; Ceroni, F.
10.1101/2022.10.19.512661 — synthetic biology — Posted on 2022-10-19
1762 ResFinderFG v2.0: a database of antibiotic resistance genes obtained by functional metagenomics
Gschwind, R.; Ugarcina Perovic, S.; Petitjean, M.; Lao, J.; Coelho, L. P.; Ruppe, E.
10.1101/2022.10.19.512667 — microbiology — Posted on 2022-10-19
1763 Timing and magnitude of the type-I interferon response are determinants of disease tolerance in arbovirus infection
Hardy, A.; Bakshi, S.; Furnon, W.; MacLean, O.; Gu, Q.; Varjak, M.; Varela, M.; Aziz, M. A.; Shaw, A.; Pinto, R. M.; Ruiz, N. C.; Mullan, C.; Taggart, A.; Filipe, A.; Randall, R. E.; Wilson, S.; Stewart, M.; Palmarini, M.
10.1101/2022.10.19.512818 — microbiology — Posted on 2022-10-19
1769 Nuclear speckle-localized RNAs exhibit preferential positioning and orientation
Paul, S.; Arias, M. A.; Wen, L.; Liao, S. E.; Zhang, J.; Wang, X.; Regev, O.; Fei, J.
10.1101/2022.10.17.512423 — biophysics — Posted on 2022-10-19
1770 Patient-derived extracellular matrix demonstrates role of COL3A1 in blood vessel mechanics
Doherty, E. L.; Aw, W. Y.; Warren, E. C.; Hockenberry, M.; Krohn, G.; Howell, S. D.; Diekman, B. O.; Legant, W. R.; Nia, H. T.; Hickey, A.; Polacheck, W. J.
10.1101/2022.10.16.512399 — bioengineering — Posted on 2022-10-19
1771 Rosetta 's Predictive Ability for Low-Affinity Ligand Binding in Fragment-Based Drug Discovery
Okwei, E.; Smith, S.; Bender, B. J.; Allison, B.; Ganguly, S.; Geanes, A.; Zhang, X.; Ledwitch, K.; Meiler, J.
10.1101/2022.10.18.512794 — biochemistry — Posted on 2022-10-19
1775 cis-eQTL mapping of TB-T2D comorbidity elucidates the involvement of African ancestry in TB susceptibility
Swart, Y.; Uren, C.; Eckold, C.; Cliff, J. M.; Malherbe, S. T.; Ronacher, K.; Kumar, V.; Wijmenga, C.; Dockrell, H.; van Crevel, R.; Walzl, G.; Kleynhans, L.; Möller, M.
10.1101/2022.10.19.512814 — genetics — Posted on 2022-10-19
1779 Systematic Analysis of the Functional Overlap among Plant YTHDF proteins
Flores-Tellez, D.; Tankmar, M. D.; Chen, J.; Brodersen, P.; Arribas-Hernandez, L.
10.1101/2022.10.19.512826 — molecular biology — Posted on 2022-10-19
1780 Raw milk kefir: microbiota, bioactive peptides, and immune modulation.
Baars, T.; van Esch, B.; van Ooijen, L.; Zhang, Z.; Dekker, P.; Boeren, S.; Diks, M.; Garssen, J.; Hettinga, K.; Kort, R.
10.1101/2022.10.19.512868 — microbiology — Posted on 2022-10-19
1784 Ecological drivers of sustained enzootic yellow fever virus transmission in Brazil, 2017-2021
Silva, N. I. O.; Albery, G. F.; Arruda, M. S.; Garcia, G. F. O.; Costa, T. A.; Mello, E. M.; Moreira, G. D.; Reis, E. V.; Silva, S. A.; Silva, M. C.; Almeida, M. G.; Becker, D.; Carlson, C. J.; Vasilakis, N.; Hanley, K. A.; Drumond, B. P.
10.1101/2022.10.19.512702 — microbiology — Posted on 2022-10-19
1786 Engineering High Throughput Screening Platforms of Cervical Cancer
Cadena, I. A.; Buchanan, M. R.; Harris, C. G.; Jenne, M. A.; Rochefort, W. E.; Nelson, D.; Fogg, K. C.
10.1101/2022.10.16.512447 — bioengineering — Posted on 2022-10-19
1789 The humoral and cellular immune response of a third dose adenoviral-based vectored vaccine after a single or 2 shots of inactivated COVID-19 vaccine in healthy adults.
Suparak, S.; Bumroongthai, K.; Jantapalaboon, D.; Phairoh, P.; Wongkidakarn, S.; Yodtup, C.; Puangtubtim, W.; Pimpapai, W.; Soonthornchattrawat, S.; Dhepaksorn, P.; Mahasirimongkol, S.
10.1101/2022.10.18.512323 — immunology — Posted on 2022-10-19
1790 A tissue injury repair pathway distinct but parallel to host pathogen defense
Liu, S.; Hur, Y. H.; Cai, X.; Cong, Q.; Yang, Y.; Xu, C.; Bilate, A. M.; Gonzales, K. A. U.; Cowley, C. J.; Hurwitz, B.; Luo, J.-D.; Tseng, T.; Gur-Cohen, S.; Sribour, M.; Omelchenko, T.; Levorse, J.; Pasolli, H. A.; Thompson, C. B.; Mucida, D.; Fuchs, E.
10.1101/2022.10.18.509515 — immunology — Posted on 2022-10-19
1792 Structure of a G protein-coupled receptor with GRK2 and a biased ligand
Duan, J.; Liu, H.; Ji, Y.; Yuan, Q.; Li, X.; Wu, K.; Gao, T.; Zhu, S.; Jiang, Y.; Yin, W.; Xu, H. E.
10.1101/2022.10.19.512855 — cell biology — Posted on 2022-10-19
1794 Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis.
Kehrer, T.; Cupic, A.; Ye, C.; Yildiz, S.; Bouhhadou, M.; Crossland, N. A.; Barrall, E.; Cohen, P.; Tseng, A.; Cagatay, T.; Rathnasinghe, R.; Flores, D.; Jangra, S.; Alam, F.; Mena, N.; Aslam, S.; Saqi, A.; Marin, A.; Rutkowska, M.; Ummadi, M. R.; Pisanelli, G.; Richardson, R. B.; Veit, E. C.; Fabius, J. M. A.; Soucheray, M.; Polacco, B. J.; Evans, M. J.; Swaney, D. L.; Gonzalez-Reiche, A. S.; Sordillo, E. M.; van Bakel, H.; Simon, V.; Zuliani-Alvarez, L.; Fontoura, B. M. A.; Rosenberg, B. R.; Krogan, N. J.; Martinez-Sobrido, L.; Garcia-Sastre, A.; Miorin, L.
10.1101/2022.10.18.512708 — microbiology — Posted on 2022-10-19
1795 Regional epidemic dynamics and Delta variant diversity resulted in varying rates of spread of Omicron-BA.1 in Mexico
Zarate, S.; Taboada, B.; Rosales-Rivera, M.; Garcia-Lopez, R.; Munoz-Medina, J. E.; Sanchez-Flores, A.; Herrera-Estrella, A.; Gomez-Gil, B.; Mojica, N. S.; Salas-Lais, A. G.; Vazquez-Perez, J. A.; Cabrera-Gaytan, D. A.; Fernandes-Matano, L.; Uribe-Noguez, L. A.; Chale-Dzul, J. B.; Maldonado Meza, B. I.; Mejia-Nepomuceno, F.; Perez-Padilla, R.; Gutierrez-Rios, R. M.; Loza, A.; Lopez, S.; Arias, C. F.
10.1101/2022.10.18.512746 — microbiology — Posted on 2022-10-19
1796 A collaborative approach to improving representation in viral genomic surveillance
Kim, P.; Kim, A. Y.; Newman, J. J.; Cella, E.; Bishop, T. C.; Huwe, P. J.; Uchakina, O. N.; McKallip, R. J.; Mack, V. L.; Hill, M. P.; Ogungbe, I. V.; Adeyinka, O.; Jones, S.; Ware, G.; Carroll, J. L.; Sawyer, J. F.; Densmore, K. H.; Foster, M.; Valmond, L.; Thomas, J.; Azarian, T.; Queen, K.; Kamil, J. P.
10.1101/2022.10.19.512816 — microbiology — Posted on 2022-10-19
1798 The Opto-inflammasome in zebrafish: a tool to study cell and tissue responses to speck formation and cell death
Hasel de Carvalho, E.; Dharmadhikari, S.; Leptin, M.; Shkarina, K.; Broz, P.; Xiong, J. R.; Reversade, B.
10.1101/2022.10.19.512883 — immunology — Posted on 2022-10-19
1803 "Organoid-in-a-column" coupled on-line with liquid chromatography-mass spectrometry
Kogler, S.; Aizenshtadt, A.; Harrison, S.; Skottvoll, F. S.; Berg, H. E.; Abadpour, S.; Scholz, H.; Sullivan, G.; Thiede, B.; Lundanes, E.; Bogen, I. L.; Krauss, S.; Roberg-Larsen, H.; Wilson, S. R.
10.1101/2020.09.08.282756 — bioengineering — Posted on 2022-10-19
1804 Data-Dependent Acquisition with Precursor Coisolation Improves Proteome Coverage and Measurement Throughput for Label-Free Single-Cell Proteomics
Truong, T.; Johnston, S. M.; Webber, K.; Boekweg, H.; Lundgren, C.; Liang, Y.; Nydegger, A.; Xie, X.; Payne, S. H.; Kelly, R. T.
10.1101/2022.10.18.512791 — cell biology — Posted on 2022-10-19
1806 Prevention of thrombocytopenia and thrombosis in heparin-induced thrombocytopenia (HIT) using deglycosylated KKO: A novel therapeutic?
Sarkar, A.; Khandelwal, S.; Kim, H.; Gruel, Y.; Rollin, J.; Wool, G. D.; Arepally, G. M.; Cines, D. B.; Rauova, L.; Poncz, M.
10.1101/2022.10.19.512755 — cell biology — Posted on 2022-10-19
1807 Centriolar subdistal appendages promote double strand break repair through homologous recombination
Rodriguez-Real, G.; Prados-Carvajal, R.; Bayona-Feliu, A.; Balestra, F. R.; Huertas, P.
10.1101/2022.10.19.512819 — cell biology — Posted on 2022-10-19
1808 7SK methylation Promotes Transcriptional Activity
Alarcon, C. R.; Perez-Pepe, M.; Desotell, A. W.; Li, H.; Li, W.; Han, B.; Lin, Q.; Klein, D. E.; Liu, Y.; Goodarzi, H.
10.1101/2022.10.17.512631 — molecular biology — Posted on 2022-10-19
1814 Molecular phenotyping of single pancreatic islet leader beta cells by Flash-Seq
Chasbosseau, P.; Yong, F.; Delgadillo-Silva, L.; Young Lee, E.; Li, S.; Gandhi, N.; Wastin, J.; Lopez-Noriega, L.; Leclerc, I.; Ali, Y.; HUGHES, J.; Sladek, R.; Martinez-sanchez, A.; Rutter, G. A.
10.1101/2022.08.26.505442 — cell biology — Posted on 2022-10-19
1815 Transcriptional control of hgcAB by an ArsR-like regulator in Pseudodesulfovibrio mercurii ND132
Gionfriddo, C. M.; Soren, A.; Wymore, A. M.; Hartnett, D. S.; Podar, M.; Parks, J. M.; Elias, D. A.; Gilmour, C. C.
10.1101/2022.10.17.512643 — microbiology — Posted on 2022-10-19
1816 FDA-approved carbonic anhydrase inhibitors reduce Amyloid beta pathology and improve cognition, by ameliorating cerebrovascular health and glial fitness
Canepa, E.; Parodi-Rullan, R.; Vazquez-Torres, R.; Gamallo-Lana, B.; Guzman-Hernandez, R.; Lemon, N. L.; Angiulli, F.; Debure, L.; Ilies, M.; Ostergaard, L.; Wisniewski, T.; Gutierrez-Jimenez, E.; Mar, A.; Fossati, S.
10.1101/2022.07.19.500681 — neuroscience — Posted on 2022-10-19
1817 Triggered functional dynamics of AsLOV2 by time-resolved electron paramagnetic resonance at high magnetic fields
Maity, S.; Price, B. D.; Wilson, C. B.; Mukherjee, A.; Starck, M.; Parker, D.; Wilson, M. Z.; Lovett, J. E.; Han, S.; Sherwin, M. S.
10.1101/2022.10.12.511365 — biophysics — Posted on 2022-10-19
1825 miR-34c-3p regulates PKA activity independent of cAMP via ablation of PRKAR2B in Theileria annulata-infected leukocytes
Haidar, M.; Tajeri, S.; Momeux, L.; Mourier, T.; mfarrej, s.; Benrached, F.; RCHIAD, Z.; Pain, A.; Langsley, G.
10.1101/2020.04.11.037341 — cell biology — Posted on 2022-10-19
1826 Antiviral immune response reveals host-specific virus infections in natural ant populations
Viljakainen, L.; Fuerst, M. A.; Grasse, A. V.; Jurvansuu, J.; Oh, J.; Tolonen, L.; Eder, T.; Rattei, T.; Cremer, S.
10.1101/2022.10.17.512467 — microbiology — Posted on 2022-10-19
1827 Identification of 2-amino benzothiazoles with bactericidal activity against Mycobacterium tuberculosis
Bonnett, S. A.; Jee, J.-A.; Chettiar, S.; Ovechkina, Y.; Korkegian, A.; Greve, E.; Odingo, J.; Parish, T.
10.1101/2022.09.23.509298 — microbiology — Posted on 2022-10-19
1828 Type I PRMT inhibitor MS023 promotes SMN2 exon 7 inclusion and synergizes with nusinersen to rescue the phenotype of SMA mice
Kordala, A. J.; Ahlskog, N.; Hanifi, M.; Stoodley, J.; Lim, W. F.; Hammond, S.; Wood, M. J.; Rinaldi, C.
10.1101/2022.10.18.512489 — neuroscience — Posted on 2022-10-19
1829 Hippocampal theta and episodic memory
Rudoler, J. H.; Herweg, N. A.; Kahana, M. J.
10.1101/2022.03.13.484014 — neuroscience — Posted on 2022-10-19
1831 The trans-zeatin-type side-chain modification of cytokinins controls rice growth
Kiba, T.; Mizutani, K.; Nakahara, A.; Takebayashi, Y.; Kojima, M.; Hobo, T.; Osakabe, Y.; Osakabe, K.; Sakakibara, H.
10.1101/2022.09.25.509405 — plant biology — Posted on 2022-10-19
1833 PROTAC-mediated selective degradation of cytosolic soluble epoxide hydrolase enhances ER-stress reduction
Wang, Y.; Morisseau, C.; Takamura, A.; Wan, D.; Li, D.; Sidoli, S.; Yang, J.; Wolan, D. W.; Hammock, B. D.; Kitamura, S.
10.1101/2022.01.20.477134 — biochemistry — Posted on 2022-10-19
1834 Rapid weed adaptation and range expansion in response to agriculture over the last two centuries
Kreiner, J. M.; Latorre, S. M.; Burbano, H. A.; Stinchcombe, J. R.; Otto, S. P.; Weigel, D.; Wright, S. I.
10.1101/2022.02.25.482047 — evolutionary biology — Posted on 2022-10-19
1835 Receptor-interacting protein kinase-3 mediates both myopathy and cardiomyopathy in preclinical animal models of Duchenne muscular dystrophy
Bencze, M.; Periou, B.; Punzon, I.; Barthelemy, I.; Taglietti, V.; Hou, C.; Zaidan, L.; Kefi, K.; Blot, S.; Agbulut, O.; Gervais, M.; Derumeaux, G.; Tiret, L.; Authier, F. J.; Relaix, F.
10.1101/2022.01.06.475271 — cell biology — Posted on 2022-10-19
1837 Oxidative reactions catalyzed by hydrogen peroxide produced by Streptococcus pneumoniae and other Streptococci Cause the Release and Degradation of Heme from Hemoglobin
Alibayov, B.; Scasny, A.; Khan, F.; Creel, A.; Smith, P.; Jop Vidal, A. G.; Fitisemanu, F. M.; Teresita Padilla-Benavides, T.; Weiser, J. N.; Vidal, J. E.
10.1101/2022.08.23.504964 — microbiology — Posted on 2022-10-19
1838 Intrinsic timescales in the visual cortex change with selective attention and reflect spatial connectivity
Zeraati, R.; Shi, Y.-L.; Steinmetz, N. A.; Gieselmann, M. A.; Thiele, A.; Moore, T.; Levina, A.; Engel, T. A.
10.1101/2021.05.17.444537 — neuroscience — Posted on 2022-10-19
1840 Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease relevant pathologies
Murtaza, N.; Cheng, A. A.; Brown, C. O.; Meka, D. P.; Hong, S.; Uy, J. A.; El-Hajjar, J.; Pipko, N.; Unda, B. K.; Schwanke, B.; Xing, S.; Thiruvahindrapuram, B.; Worrawat, E.; Trost, B.; Deneault, E.; Calderon de Anda, F.; Doble, B. W.; Ellis, J.; Anagnostou, E.; Bader, G. D.; Scherer, S. W.; Lu, Y.; Singh, K. K.
10.1101/2022.01.17.476220 — neuroscience — Posted on 2022-10-19
1841 Aromatic ring flips in differently packedubiquitin protein crystals from MAS NMR andMD
Gauto, D. F.; Lebedenko, O. O.; Becker, L. M.; Ayala, I.; Lichtenecker, R.; Skrynnikov, N. R.; Schanda, P.
10.1101/2022.07.07.499110 — biophysics — Posted on 2022-10-19
1843 Single-cell genomics reveals region-specific developmental trajectories underlying neuronal diversity in the human hypothalamus
Herb, B. R.; Glover, H. J.; Bhaduri, A.; Colantuoni, C.; Bale, T. L.; Siletti, K.; Linnarsson, S.; Hodge, R. D.; Lein, E.; Kriegstein, A.; Doege, C.; Ament, S. A.
10.1101/2021.07.20.453090 — neuroscience — Posted on 2022-10-19
1844 Lipid metabolism dysfunction following symbiont elimination is linked to altered Kennedy pathway homeostasis
Attardo, G. M.; Benoit, J.; Michalkova, V.; Kondragunta, A.; Baumann, A.; Weiss, B.; Malacrida, A.; Scolari, F.; Aksoy, S.
10.1101/2022.08.23.504685 — physiology — Posted on 2022-10-19
1845 Novel plasma exosome biomarkers for prostate cancer progression in co-morbid metabolic disease
Jafari, N.; Chen, A.; Kolla, M.; Pompa, I. R.; Qiu, Y.; Yu, R.; Llevenes, P.; Ennis, C. S.; Mori, J.; Mahdaviani, K.; Halpin, M.; Gignac, G. A.; Heaphy, C. M.; Monti, S.; Denis, G. V.
10.1101/2022.02.01.478722 — cancer biology — Posted on 2022-10-19
1847 Cell type- and state- resolved immune transcriptomic profiling identifies glucocorticoid-responsive molecular defects in multiple sclerosis T cells
Roostaei, T.; Sabrin, A.; Kivisäkk, P.; McCabe, C.; Nejad, P.; Felsky, D.; Touil, H.; Vlachos, I. S.; Hui, D.; Fransson, J.; Patsopoulos, N. A.; Kuchroo, V. K.; Zujovic, V.; Weiner, H. L.; Klein, H.-U.; De Jager, P. L.
10.1101/2022.06.29.498195 — genomics — Posted on 2022-10-19
1849 A Leaky Human Colon Model Reveals Uncoupled Apical/Basal Cytotoxicity in Early Clostridioides difficile Toxin Exposure
Ok, M. T.; Liu, J.; Bliton, R. J.; Hinesley, C. M.; San Pedro, E. E. T.; Breau, K. A.; Gomez-Martinez, I.; Burclaff, J.; Magness, S. T.
10.1101/2022.10.13.511617 — cell biology — Posted on 2022-10-19
1852 In vitro modelling of oral microbial invasion in the human colon
Etienne Mesmin, L.; Meslier, V.; Uriot, O.; Fournier, E.; Deschamps, C.; Denis, S.; David, A.; Jegou, S.; Morabito, C.; Quinquis, B.; Thirion, F.; Plaza Onate, F.; Le Chatelier, E.; Ehrlich, S. D.; Blanquet-Diot, S.; Almeida, M.
10.1101/2022.10.17.512642 — microbiology — Posted on 2022-10-19
1853 Natural Variation in Brachypodium distachyon Responses to Combined Abiotic Stresses
Ludwig, E.; Polydore, S.; Berry, J.; Sumner, J.; Ficor, T.; Agnew, E.; Haines, K.; Greenham, K.; Fahlgren, N.; Mockler, T. C.; Gehan, M. A.
10.1101/2022.10.14.512283 — plant biology — Posted on 2022-10-19
1854 Older Women with lower lean mass values have hypermethylated sites in the PI3K-Akt pathway
Correia, I. M.; Rodrigues, G. d. S.; Noronha, N. Y.; de Almeida, M. L.; da Silva Sobrinho, A. C.; Nonino, C. B.; Junior, C. R. B.
10.1101/2022.10.14.512202 — genetics — Posted on 2022-10-19
1856 A marmoset brain cell census reveals persistent influence of developmental origin on neurons
Krienen, F. M.; Levandowski, K. M.; Zaniewski, H.; del Rosario, R. C.; Schroeder, M. E.; Goldman, M.; Lutservitz, A.; Zhang, Q.; Li, K. X.; Beja-Glasser, V. F.; Sharma, J.; Shin, T. W.; Mauermann, A.; Wysoker, A.; Nemesh, J.; Kashin, S.; Vergara, J.; Chelini, G.; Dimidschstein, J.; Berretta, S.; Boyden, E.; McCarroll, S. A.; Feng, G.
10.1101/2022.10.18.512442 — neuroscience — Posted on 2022-10-19
1858 Single-cell molecular profiling using ex vivo functional readouts fuels precision oncology in glioblastoma
Panovska, D.; Nazari, P.; Cole, B.; Creemers, P.-J.; Derweduwe, M.; Solie, L.; Van Gassen, S.; Claeys, A.; Verbeke, T.; Saeys, Y.; Van Der Planken, D.; Bosisio, F. M.; Put, E.; Bamps, S.; Clement, P.; Verfaillie, M.; Sciot, R.; Ligon, K. L.; De Vleeschouwer, S.; Martinez, A.; De Smet, F.
10.1101/2022.10.17.512525 — cancer biology — Posted on 2022-10-19
1859 MLL1 regulates cytokine-driven cell migration and metastasis
Nair, P. R.; Danilova, L.; Gomez-de-Mariscal, E.; Kim, D.; Fan, R.; Munoz-Barrutia, A.; Fertig, E. J.; Wirtz, D.
10.1101/2022.10.18.512715 — cancer biology — Posted on 2022-10-19
1861 The epigenetic modifier DOT1L regulates gene regulatory networks necessary for cardiac patterning and cardiomyocyte cell cycle withdrawal
Cattaneo, P.; Hayes, M. G.; Baumgarten, N.; Hecker, D.; Peruzzo, S.; Kunderfranco, P.; Larcher, V.; Zhang, L.; Contu, R.; Fonseca, G.; Spinozzi, S.; Chen, J.; Condorelli, G.; Schulz, M. H.; Guimaraes-Camboa, N.; Evans, S. M.
10.1101/2022.10.18.512679 — developmental biology — Posted on 2022-10-19
1863 A Vaccinia-based system for directed evolution of GPCRs in mammalian cells
Klenk, C.; Scrivens, M.; Niederer, A.; Shi, S.; Mueller, L.; Gersz, E.; Zauderer, M.; Smith, E.; Strohner, R.; Plückthun, A.
10.1101/2022.10.17.512578 — biochemistry — Posted on 2022-10-18
1864 Targeting the BAG-1 family of co-chaperones in lethal prostate cancer.
Neeb, A.; Figueiredo, I.; Bogdan, D.; Cato, L.; Strober, J.; Jimenez-Vacas, J. M.; Gourain, V.; Lee, I.; Seeger, R.; Muhle-Goll, C.; Gurel, B.; Welti, J.; Nava-Rodrigues, D.; Rekowski, J.; Qiu, X.; Jiang, Y.; Di Micco, P.; Mateos, B.; Bielskute, S.; Riisnaes, R.; Ferreira, A.; Miranda, S.; Crespo, M.; Buroni, L.; Ning, J.; Brases, S.; Jing, N.; Graessle, S.; Metzger, D.; Swain, A.; Salvatella, X.; Plymate, S.; Al-Lazaikani, B.; LONG, H. W.; Yuan, W.; Brown, M.; Cato, A.; de Bono, J.; Sharp, A.
10.1101/2022.10.17.512378 — molecular biology — Posted on 2022-10-18
1866 Absence of Staphylococcus aureus in wild populations of fish supports a spillover hypothesis
Matuszewska, M.; Dabrowska, A.; Murray, G. G.; Kett, S. M.; Vick, A. J.; Banister, S. C.; Pantoja Munoz, L.; Cunningham, P.; Welch, J. J.; Holmes, M. A.; Weinert, L. A.
10.1101/2022.10.18.512561 — microbiology — Posted on 2022-10-18
1870 Molecular programs of regional specification and neural stem cell fate progression in developing macaque telencephalon
Micali, N.; Ma, S.; Li, M.; Kim, S.-K.; Mato-Blanco, X.; Sindhu, S.; Arellano, J. I.; Gao, T.; Duque, A.; Santpere, G.; Sestan, N.; Rakic, P.
10.1101/2022.10.18.512724 — neuroscience — Posted on 2022-10-18
1875 Development of the visual system in social poison frog tadpoles
Butler, J. M.; McKinney, J.; Ludington, S. C.; Mabogunje, M.; Singh, D.; Edwards, S. V.; O'Connell, L. A.
10.1101/2022.10.18.512729 — developmental biology — Posted on 2022-10-18
1877 7SK methylation Promotes Transcriptional Activity upon Growth Factor Stimulation
Alarcon, C. R.; Perez-Pepe, M.; Desotell, A. W.; Li, H.; Li, W.; Han, B.; Lin, Q.; Klein, D. E.; Liu, Y.; Goodarzi, H.
10.1101/2022.10.17.512631 — molecular biology — Posted on 2022-10-18
1881 The Prophylactic and Therapeutic Efficacy of the Broadly Active Antiviral Ribonucleoside N4-Hydroxycytidine (EIDD-1931) in a Mouse Model of Lethal Ebola Virus Infection
Bluemling, G. R.; Mao, S.; Natchus, M. G.; Painter, W.; Mulangu, S.; Lockwood, M.; De La Rosa, A. D. L. R.; Brasel, T.; Comer, J. E.; Freiberg, A. N.; Kolykhalov, A.; Painter, G. R.
10.1101/2022.10.18.512767 — microbiology — Posted on 2022-10-18
1886 Abundant Aβ fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer's disease brains
Stern, A. M.; Yang, Y.; Meunier, A. L.; Liu, W.; Cai, Y.; Ericsson, M.; Liu, L.; Goedert, M.; Scheres, S. H.; Selkoe, D. J.
10.1101/2022.10.18.512754 — neuroscience — Posted on 2022-10-18
1888 Chronic activation of dopaminergic neurons via bioluminescence-optogenetics provides neuroprotection in a rodent model of Parkinson's disease
Shiu, F. H.; Skelton, H.; Berglund, K.; Fernandez, A. M.; Gutekunst, C.-A. N.; Robinson, E. R.; Wang, Z.; Gross, R. E.
10.1101/2022.10.17.512538 — neuroscience — Posted on 2022-10-18
1890 Snf1/AMPK fine-tunes TORC1 signaling in response to glucose starvation
Caligaris, M.; Nicastro, R.; Hu, Z.; Tripodi, F.; Hummel, J. E.; Deprez, M.-A.; Winderickx, J.; Rospert, S.; Coccetti, P.; Dengjel, J.; De Virgilio, C.
10.1101/2022.10.18.512649 — biochemistry — Posted on 2022-10-18
1894 Transcriptional control of hgcAB by an ArsR-like regulator in Pseudodesulfovibrio mercurii ND132
Gionfriddo, C. M.; Soren, A.; Wymore, A. M.; Hartnett, D. S.; Podar, M.; Parks, J. M.; Elias, D. A.; Gilmour, C. C.
10.1101/2022.10.17.512643 — microbiology — Posted on 2022-10-18
1895 SituSeq: An offline protocol for rapid and remote Nanopore amplicon sequence analysis
Zorz, J.; Li, C.; Chakraborty, A.; Gittins, D.; Surcon, T.; Morrison, N.; Bennett, R.; MacDonald, A.; Hubert, C. R.
10.1101/2022.10.18.512610 — microbiology — Posted on 2022-10-18
1896 Purine and carbohydrate availability drive Enterococcus faecalis fitness during wound infection
Tan, C. A. Z.; Chong, K. K. L.; Yeong, D. Y. X.; Ng, C. H. M.; Ismail, M. H.; Tay, V. S. Y.; Ali, Y.; Kline, K. A.
10.1101/2022.10.17.512645 — microbiology — Posted on 2022-10-18
1897 Alcanivorax borkumensis Biofilms Enhance Oil Degradation By Interfacial Tubulation
Prasad, M.; Obana, N.; Lin, S.-Z.; Sakai, K.; Blanch-Mercader, C.; Prost, J.; Nomura, N.; Rupprecht, J.-F.; Fattaccioli, J.; Utada, A. S.
10.1101/2022.08.06.503017 — biophysics — Posted on 2022-10-18
1902 Decoding of YAP levels and dynamics by pluripotency factors
Meyer, K.; Lammers, N. C.; Bugaj, L. J.; Garcia, H. G.; Weiner, O. D.
10.1101/2022.10.17.512504 — cell biology — Posted on 2022-10-18
1904 Cellular sources and targets of type I interferons that drive susceptibility to tuberculosis
Kotov, D. I.; Lee, O. V.; Langner, C.; Guillen, J. V.; Peters, J. M.; Moon, A.; Burd, E. M.; Witt, K. C.; Stetson, D. B.; Jaye, D. L.; Bryson, B. D.; Vance, R. E.
10.1101/2022.10.06.511233 — immunology — Posted on 2022-10-18
1906 Altered plasma membrane abundance of the sulfatide-binding protein NF155 links glycosphingolipid imbalances to demyelination
McKie, S. J.; Nicholson, A. S.; Smith, E.; Fawke, S.; Caroe, E.; Williamson, J. C.; Butt, B. G.; Kolarov, D.; Peterka, O.; Holcapek, M.; Lehner, P. J.; Graham, S. C.; Deane, J. E.
10.1101/2022.09.15.508082 — neuroscience — Posted on 2022-10-18
1907 Linking neuronal and hemodynamic network signatures in the resting human brain
Elshahabi, A.; Ethofer, s.; Lerche, H.; van de Velden, D.; Wehrl, H.; la Fougere, C.; Braun, C.; Focke, N. K.
10.1101/2022.08.28.505586 — neuroscience — Posted on 2022-10-18
1908 Vitamin B2 enables peroxisome proliferator-activated receptor α regulation of fasting glucose availability
Masschelin, P. M.; Saha, P.; Ochsner, S. A.; Cox, A. R.; Kim, K. H.; Felix, J. B.; Sharp, R.; Li, X.; Tan, L.; Park, J. H.; Wang, L.; Putluri, V.; Lorenzi, P. L.; Nuotio-Antar, A. M.; Sun, Z.; Kiapparettu, B. A.; Putluri, N.; Moore, D.; Summers, S. A.; McKenna, N. J.; Hartig, S. M.
10.1101/2022.10.16.512439 — physiology — Posted on 2022-10-18
1910 In situ imaging across ecosystems to resolve the fine-scale oceanographic drivers of a globally significant planktonic grazer
Greer, A. T.; Schmid, M. S.; Duffy, P. I.; Robinson, K. L.; Genung, M. A.; Luo, J. Y.; Panaiotis, T.; Briseno-Avena, C.; Frischer, M. E.; Sponaugle, S.; Cowen, R. K.
10.1101/2022.08.31.506093 — ecology — Posted on 2022-10-18
1912 Tactile perception of auditory roughness
Bernard, C.; Kronland-Martinet, R.; Fery, M.; Ystad, S.; Thoret, E.
10.1101/2022.10.16.512429 — neuroscience — Posted on 2022-10-18
1914 HumanBrainAtlas: an in vivo MRI dataset for detailed segmentations
Schira, M. M.; Isherwood, Z. J.; Kassem, M. S.; Barth, M.; Shaw, T. B.; Roberts, M. M.; Paxinos, G.
10.1101/2022.10.16.511844 — neuroscience — Posted on 2022-10-18
1915 Sex-dimorphic neuroprotective effect of CD163 in an alpha-synuclein mouse model Of Parkinson's disease
Ferreira, S. A.; Li, C.; Klaestrup, I. H.; Toft, G. U.; Betzer, C.; Svedsen, P.; Jensen, P. H.; Luo, Y.; Etzerodt, A.; Moestrup, S. K.; Romero-Ramos, M.
10.1101/2022.10.17.512526 — neuroscience — Posted on 2022-10-18
1917 Electro-acupuncture alleviates ACE-increased anxiety-like behaviors in mice of adulthood by targeting claustrum D1R CaMKII
Chen, L.; Liu, Z.; Zhao, Z.; Pan, W.; Hu, T.; Wei, X.; Nie, J.; Ge, F.; Ding, J.; Fan, Y.; Kim, H. Y.; Guan, X.
10.1101/2022.10.18.512685 — neuroscience — Posted on 2022-10-18
1918 Characterization of the Tau Interactome in Human Brain Reveals Isoform-Dependent Interaction with 14-3-3 Family Proteins
Betters, R. K.; Luhmann, E.; Gottschalk, A. C.; Xu, Z.; Ptak, C.; Fiock, K. L.; Radoshevich, L.; Hefti, M. M.
10.1101/2022.10.17.512532 — neuroscience — Posted on 2022-10-18
1919 TPLATE complex dependent endocytosis is required for shoot apical meristem maintenance by 1 attenuating CLAVATA1 signaling
Wang, J.; Jiang, Q.; Pleskot, R.; Grones, P.; Denay, G.; Ampudia, C. G.; Bahafid, E.; Xu, X.; Vandorpe, M.; Mylle, E.; De Smet, I. D.; VERNOUX, T.; Simon, R.; Nowack, M.; Van Damme, D.
10.1101/2022.10.16.511936 — plant biology — Posted on 2022-10-18
1920 A context-dependent switch from sensing to feeling in the primate amygdala
Martin, A. B.; Cardenas, M. A.; Anderson, R. K.; Bowman, A. I.; Hillier, E. A.; Bensmaia, S. J.; Fuglevand, A. J.; Gothard, K. M.
10.1101/2022.10.15.512319 — neuroscience — Posted on 2022-10-18
1922 Myeloid deficiency of the intrinsic clock protein Bmal1 accelerates cognitive aging by disrupting microglial synaptic pruning
Iweka, C. A.; Seigneur, E. M.; Hernandez, A. L.; Herrera Paredes, S.; Cabrera, M.; Blacher, E.; Pasternak, C.; Longo, F.; de Lecea, L.; Andreasson, K.
10.1101/2022.10.17.512618 — neuroscience — Posted on 2022-10-18
1923 Type I PRMT inhibitor MS023 promotes SMN2 exon 7 inclusion and synergizes with nusinersen to rescue the phenotype of SMA mice
Kordala, A. J.; Ahlskog, N.; Hanifi, M.; Stoodley, J.; Lim, W. F.; Hammond, S.; Wood, M. J.; Rinaldi, C.
10.1101/2022.10.18.512489 — neuroscience — Posted on 2022-10-18
1924 High-throughput screening identifies small molecule inhibitors of thioesterase superfamily member 1: Implications for the management of non-alcoholic fatty liver disease
Krumm, C. S.; Ramos-Espiritu, L.; Landzberg, R. S.; Adura, C.; Liu, X.; Acuna, M.; Xie, Y.; Xu, X.; Tillman, M. C.; Li, Y.; Glickman, F.; Ortlund, E. A.; Ginn, J. D.; Cohen, D. E.
10.1101/2022.10.15.512369 — pharmacology and toxicology — Posted on 2022-10-18
1925 The Children's Brain Tumor Network (CBTN) - Accelerating Research in Pediatric Central Nervous System Tumors through Collaboration and Open Science
Lilly, J. V.; Rokita, J. L.; Mason, J. L.; Patton, T.; Stefankiewiz, S.; Higgins, D.; Trooskin, G.; Larouci, C. A.; Arya, K.; Appert, E.; Heath, A. P.; Zhu, Y.; Brown, M. A.; Zhang, B.; Farrow, B. K.; Robins, S.; Morgan, A. M.; Nguyen, T. Q.; Frenkel, E.; Lehmann, K.; Drake, E.; Sullivan, C.; Plisiewicz, A.; Coleman, N.; Patterson, L.; Koptyra, M.; Helili, Z.; Van Kuren, N.; Young, N. M.; Kim, M. C.; Friedman, C.; Lubneuski, A.; Blackden, C.; Williams, M.; Baubet, V.; Tauhid, L.; Galanaugh, J.; Boucher, K.; Ijaz, H.; Cole, K. A.; Choudhari, N.; Santi, M.; Moulder, R. W.; Waller, J.; Rife, W.;
10.1101/2022.10.14.511975 — cancer biology — Posted on 2022-10-18
1928 Immature Myeloid Cell Deposition in Old Bone Marrow Revealed by Single-Cell Transcriptome Analysis
Kim, W. J.; Kim, K.-T.; Moon, J.-I.; Park, S. G.; Cho, Y.-D.; Kim, H. J.; Shin, H.-R.; Yoon, H.; Ryoo, H.-M.
10.1101/2022.10.15.512392 — bioinformatics — Posted on 2022-10-18
1934 CD46 targeted 212Pb alpha particle radioimmunotherapy for prostate cancer treatment
Li, J.; Huang, T.; Hua, J.; Wang, Q.; Su, Y.; Chen, P.; Bidlingmaier, S.; Li, A.; Xie, Z.; Bidkar, A.; Shen, S.; Shi, W.; Seo, Y.; Flavell, R. R.; Gioeli, D.; Dreicer, R.; Li, H.; Liu, B.; He, J.
10.1101/2022.10.14.512321 — bioengineering — Posted on 2022-10-18
1935 Glycolytic reprogramming underlies immune cell activation by polyethylene wear particles
Maduka, C. V.; Habeeb, O. M.; Kuhnert, M. M.; Hakun, M.; Goodman, S. B.; Contag, C. H.
10.1101/2022.10.14.512318 — bioengineering — Posted on 2022-10-18
1940 MCRS1 modulates the heterogeneity of microtubule minus-end morphologies in mitotic spindles
Laguillo-Diego, A.; Kiewisz, R.; Marti-Gomez, C.; Baum, D.; Muller-Reichert, T.; Vernos, I.
10.1101/2022.06.03.494715 — cell biology — Posted on 2022-10-18
1942 Supervised Machine Learning Enables Geospatial Microbial Provenance
Bhattacharya, C.; Tierney, B. T.; Ryon, K. A.; Bhattacharyya, M.; Hastings, J. J. A.; Basu, S.; Bhattacharya, B.; Bagchi, D.; Mukherjee, S.; Wang, L.; Henaff, E. M.; Mason, C.
10.1101/2022.09.16.508347 — microbiology — Posted on 2022-10-18
1943 Immunofilaments Provide a Nanoscale Platform for In Vivo T Cell Expansion and Cancer Immunotherapy
Weiss, L.; Weiden, J.; Dölen, Y.; Grad, E.; van Dinther, E. A. W.; Schluck, M.; Eggermont, L. J.; van Mierlo, G.; Gileadi, U.; Bartolo-Ibars, A.; Raave, R.; Gorris, M. A. J.; Verrijp, K.; Valente, M.; Deplancke, B.; Verdoes, M.; Benitez-Ribas, D.; Cerundolo, V.; Heskamp, S.; van Spriel, A. B.; Figdor, C. G.; Hammink, R.
10.1101/2022.10.14.512109 — immunology — Posted on 2022-10-18
1944 Adipocyte-secreted IL-6 sensitizes macrophages to IL-4 signaling
Luan, D. A.; Dadpey, B.; Zaid, J.; Bridge-Comer, P. E.; DeLuca, J. H.; Xia, W.; Castle, J.; Reilly, S. M.
10.1101/2022.07.19.500620 — immunology — Posted on 2022-10-18
1945 Encoding surprise by retinal ganglion cells
Despotovic, D. M.; Joffrois, C.; Marre, O. M.; Chalk, M.
10.1101/2022.10.15.512347 — neuroscience — Posted on 2022-10-18
1947 Surface phenotyping and quantitative proteomics reveal differentially enriched proteins of brain-derived extracellular vesicles in Parkinson's disease
Arab, T.; Huang, Y.; Nagaraj, R.; Gizzie, E.; Redding-Ochoa, J.; Troncoso, J. C.; Pletnikova, O.; Boronina, T.; Cole, R. N.; Mahairaki, V.; Routenberg, D. A.; Witwer, K. W.
10.1101/2022.10.17.512628 — neuroscience — Posted on 2022-10-18
1948 Deep learning based decoding of local field potential events
Schilling, A.; Gerum, R.; Boehm, C.; Rasheed, J.; Metzner, C.; Maier, A.; Reindl, C.; Hamer, H.; Krauss, P.
10.1101/2022.10.14.512209 — neuroscience — Posted on 2022-10-18
1952 Effects of Neurofeedback training on performance in laboratory tasks: A systematic review
Chiasson, P.; Boylan, M. R.; Elhamiasl, M.; Pruitt, J. M.; Ranjan, S.; Riels, K.; Sahoo, A. K.; Mirifar, A.; Keil, A.
10.1101/2022.10.14.511990 — neuroscience — Posted on 2022-10-18
1956 An Extensible Vector Toolkit and Parts Library for Advanced Engineering of Plant Genomes
Chamness, J. C.; Kumar, J.; Cruz, A. J.; Rhuby, E.; Holum, M. J.; Cody, J. P.; Tibebu, R.; Gamo, M. E.; Starker, C. G.; Zhang, F.; Voytas, D. F.
10.1101/2022.10.15.511792 — plant biology — Posted on 2022-10-18
1958 Cyclosporin A delays the terminal disease stage in Tfam KO mice without improving mitochondrial energy production
Chatel, B.; Varlet, I.; Ogier, A.; Pecchi, E.; Bernard, M.; GONDIN, J.; Westerblad, H.; Bendahan, D.; Gineste, C.
10.1101/2022.10.14.511701 — pathology — Posted on 2022-10-18
1959 DNA Methylation Signatures in Breast Cancer: A Systematic Review and Meta-Analysis
Trasierras-Fresco, A. M.; Andreu, Z.; Hidalgo, M. R.; Gomez-Cabanes, B.; Malmierca-Merlo, P.; Romera-Giner, S.; Crespo, D.; Serna-Blasco, R.; Romero, A.; Lopez-Guerrero, J. A.; de la Iglesia Vaya, M.; Garcia-Garcia, F.
10.1101/2022.10.15.512358 — cancer biology — Posted on 2022-10-18
1961 Field dependent deep learning enables high-throughput whole-cell 3D super-resolution imaging
Fu, S.; Shi, W.; Luo, T.; He, Y.; Zhou, L.; Yang, J.; Yang, Z.; Liu, J.; Liu, X.; Guo, Z.; Yang, C.; Liu, C.; Huang, Z.-l.; Ries, J.; Zhang, M.; Xi, P.; Jin, D.; Li, Y.
10.1101/2022.10.14.512179 — biophysics — Posted on 2022-10-18
1963 Herb-paths, a network and statistical model to explore health-beneficial effects of herbs and herbal constituents
van der Voet, M.; Xu, Z.; van Rijnberk, L.; Wu, H.; Liang, W.; Sun, P.; Wang, M.; Wildwater, M.; Poppelaars, E. S.
10.1101/2022.10.14.512228 — bioinformatics — Posted on 2022-10-18
1967 The mitochondrial component of human infertility- an increased mtDNA content and an excess of ultra-rare mtDNA variants in aneuploid versus euploid embryos.
Ri, M. T.; Ree, N.; Oreshkov, S.; Tofilo, M.; Kirillova, A.; Zvereva, I.; Gunbin, K.; Yurov, V.; Salumets, A.; Woods, D. C.; Tilly, J. L.; Khrapko, K.; Fellay, J.; Mazunin, I.; Popadin, K.
10.1101/2022.10.14.512116 — bioinformatics — Posted on 2022-10-18
1971 So ManyFolds, So Little Time: Efficient Protein Structure Prediction With pLMs and MSAs
Barrett, T. D.; Villegas-Morcillo, A.; Robinson, L.; Gaujac, B.; Admete, D.; Saquand, E.; Beguir, K.; Flajolet, A.
10.1101/2022.10.15.511553 — bioinformatics — Posted on 2022-10-18
1976 Development and validation of an AI/ML platform for the discovery of splice-switching oligonucleotide targets
Fronk, A. D.; Manzanares, M. A.; Zheng, P.; Geier, A.; Anderson, K.; Frederick, V.; Smith, S.; Gera, S.; Munch, R.; Are, M.; Dhingra, P.; Arun, G.; Akerman, M.
10.1101/2022.10.14.512313 — bioinformatics — Posted on 2022-10-18
1981 Born with intronless ERF transcriptional factors: C4 photosynthesis inherits a legacy dating back 450 million years
Lyu, M.-j. A.; Du, H.; Yao, H.; Zhang, Z.; Chen, G.; Chen, F.; Zhao, Y.-Y.; Tang, Q.; Miao, F.-F.; Wang, Y.; Zhao, Y.; Lu, H.; Fang, L.; Gao, Q.; Qi, Y.; Zhang, Q.; Zhang, J.; Yang, T.; Cui, X.; Liang, C.; Lu, T.; Zhu, X.-G.
10.1101/2022.10.14.512192 — evolutionary biology — Posted on 2022-10-18
1986 The Vogt-Bailey index: a local gradient analysis
Farrugia, C.; Arenzana Irazu, I.; Scerri, K.; Bajada, C. J.
10.1101/2022.10.14.511925 — neuroscience — Posted on 2022-10-18
1987 Canonical and Non-Canonical Psychedelic Drugs Induce Common Network Changes in Human Cortex
Dai, R.; Larkin, T. E.; Huang, Z.; Tarnal, V.; Picton, P.; Vlisides, P. E.; Janke, E.; McKinney, A.; Hudetz, A. G.; Harris, R. E.; Mashour, G. A.
10.1101/2022.10.14.512285 — neuroscience — Posted on 2022-10-18
1992 Green leaf volatiles co-opt proteins involved in molecular pattern signaling in plant cells
Tanarsuwongkul, S.; Fisher, K. W.; Mullis, B. T.; Roberts, J.; Negi, H.; Wang, Q.; Stratmann, J. W.
10.1101/2022.10.15.512371 — plant biology — Posted on 2022-10-18
1993 High-frequency synthetic apomixis in hybrid rice
Vernet, A.; Meynard, D.; Lian, Q.; Mieulet, D.; Gibert, O.; Bissah, M.; Rivallan, R.; Meunier, A.-c.; Shankle, K.; Frouin, J.; Shankle, K.; Khanday, I.; Mercier, R.; Sundaresan, V.; Guiderdoni, E.
10.1101/2022.10.14.512232 — plant biology — Posted on 2022-10-18
1994 Single-gene resolution of diversity-driven community overyielding
Wuest, S. E.; Schulz, L.; Rana, S.; Frommelt, J.; Ehmig, M.; Pires, N. D.; Grossniklaus, U.; Hardtke, C. S.; Hammes, U.; Schmid, B.; Niklaus, P. A.
10.1101/2022.10.14.512290 — plant biology — Posted on 2022-10-18
1995 Global disparities in plant science: a legacy of colonialism, patriarchy, and exclusion
Marks, R. A.; Amezquita, E. J.; Percival, S.; Rougon-Cardoso, A.; Chibici-Revneanu, C.; Tebele, S. M.; Farrant, J. M.; Chitwood, D. H.; VanBuren, R.
10.1101/2022.10.15.512190 — plant biology — Posted on 2022-10-18
1996 Soluble VE-cadherin disrupts endothelial barrier function via VE-PTP/RhoA signalling
Knop, J.-L.; Burkard, N.; Danesh, M.; Dandekar, T.; Srivastava, M.; Hiermaier, M.; Waschke, J.; Flemming, S.; Schlegel, N.
10.1101/2022.10.17.512494 — physiology — Posted on 2022-10-18
1998 Integrated Molecular Characterization of Intraductal Papillary Mucinous Neoplasms: An NCI Cancer Moonshot Precancer Atlas Pilot Project
Semaan, A.; Bernard, V.; Wong, J.; Makino, Y.; Swartzlander, D.; Rajapakshe, K. I.; Lee, J.; Officer, A.; Schmidt, C. M.; Wu, H. H.; Scaife, C. L.; Affolter, K. E.; Nachmanson, D.; Firpo, M. A.; Yip-Schneider, M.; Lowy, A. M.; Harismendy, O.; Sen, S.; Maitra, A. A.; Jakubek, Y. A.; Guerrero, P. A.
10.1101/2022.10.14.512148 — cancer biology — Posted on 2022-10-18
2001 Predicting FDA approvability of small-molecule drugs
Huang, C.-H.; Hsu, J.; Yang, L.-y.; CHEN, T.-M.; Shih, E. S. C.; Hwang, M.-J.
10.1101/2022.10.15.512330 — bioinformatics — Posted on 2022-10-18
2002 Adaptive Sampling as tool for Nanopore direct RNA-sequencing
Naarmann-de Vries, I. S.; Gjerga, E.; Gandor, C. L. A.; Dieterich, C.
10.1101/2022.10.14.512223 — bioinformatics — Posted on 2022-10-18
2003 Transposable elements orchestrate subgenome-convergent and -divergent transcription in common wheat
Zhang, Y.; Li, Z.; Liu, J.; Zhang, Y.; Ye, L.; Peng, Y.; Wang, H.; Diao, H.; Ma, Y.; Wang, M.; Xie, Y.; Tang, T.; Zhuang, Y.; Teng, W.; Tong, Y.; Zhang, W.; Lang, Z.; Xue, Y.; Zhang, Y.
10.1101/2022.10.14.512211 — bioinformatics — Posted on 2022-10-18
2004 Overexpression of the plastidal pseudo-protease AtFtsHi3 confers drought tolerance without penalizing growth
Cook, S. D.; Mishra, L. S.; Isaksson, H.; Straub, I. R.; Abele, M.; Mishra, S.; Ludwig, C.; Libby, E.; Funk, C.
10.1101/2022.10.17.512522 — biochemistry — Posted on 2022-10-18
2007 Rubber needs to be included in deforestation-free commodity legislation
Warren-Thomas, E.; Ahrends, A.; Wang, Y.; Wang, M. M. H.; Jones, J. P. G.
10.1101/2022.10.14.510134 — ecology — Posted on 2022-10-18
2008 A metabolomic view on local climate adaptation: Latitudinal divergence of heat and drought responses in a coastal plant
Schrieber, K.; Gluesing, S.; Peters, L.; Eichert, B.; Althoff, M.; Schwarz, K.; Erfmeier, A.; Demetrowitsch, T. J.
10.1101/2022.10.14.512208 — ecology — Posted on 2022-10-18
2009 Complexity and 1/f slope jointly reflect brain states
Medel, V.; Irani, M.; Crossley, N.; Ossandon, T.; Boncompte, G.
10.1101/2020.09.15.298497 — neuroscience — Posted on 2022-10-18
2014 Collagen breaks at weak sacrificial bonds taming its mechanoradicals
Rennekamp, B.; Karfusehr, C.; Kurth, M.; Ünal, A.; Riedmiller, K.; Gryn'ova, G.; Hudson, D. M.; Gräter, F.
10.1101/2022.10.17.512491 — biophysics — Posted on 2022-10-18
2015 RNAs undergo phase transitions with lower critical solution temperatures
Wadsworth, G. M.; Zahurancik, W. J.; Zeng, X.; Pullara, P.; Lai, L. B.; Sidharthan, V.; Pappu, R. V.; Gopalan, V.; Banerjee, P. R.
10.1101/2022.10.17.512593 — biophysics — Posted on 2022-10-18
2017 Dynamic metabolome profiling uncovers potential TOR signaling genes
Reichling, S.; Doubleday, P. F.; Germade, T.; Bergmann, A.; Loewith, R.; Sauer, U.; Holbrook-Smith, D.
10.1101/2022.07.25.500770 — systems biology — Posted on 2022-10-18
2019 Comparative genomics and transcriptomic response to root exudates of six rice root-associated Burkholderia sensu lato species
Wallner, A.; Klonowska, A.; Guigard, L.; King, E.; Rimbault, I.; Ngonkeu, E. L.; Nguyen, P. V.; Bena, G.; Moulin, L.
10.1101/2022.10.04.510755 — microbiology — Posted on 2022-10-18
2020 Automated optimisation of solubility and conformational stability of antibodies and proteins
Rosace, A.; Bennett, A.; Oeller, M.; Mortensen, M. M.; Sakhnini, L. I.; Lorenzen, N.; Poulsen, C.; Sormanni, P.
10.1101/2022.05.20.492798 — biochemistry — Posted on 2022-10-18
2025 Autism-associated transcriptional regulators target shared loci proximal to brain-expressed genes.
Fazel Darbandi, S.; An, J. Y.; Lim, K.; Page, N. F.; Liang, L.; Ypsilanti, A.; Markenscoff-Papadimitriou, E.; State, M. W.; Nord, A. S.; Sanders, S. J.; Rubenstein, J. L. R.
10.1101/2022.10.17.512583 — genomics — Posted on 2022-10-18
2026 Tracking the online construction of linguistic meaning through negation
Zuanazzi, A.; Ripolles, P.; Lin, W. M.; Gwilliams, L.; King, J.-R.; Poeppel, D.
10.1101/2022.10.14.512299 — neuroscience — Posted on 2022-10-18
2027 ATGL is differentially required for adipocyte FABP4 secretion in vivo and ex vivo
Prentice, K. J.; Lee, A.; Cedillo, P.; Inouye, K. E.; Ertunc, M. E.; Lee, G. Y.; Hotamisligil, G. S.
10.1101/2022.10.14.512277 — physiology — Posted on 2022-10-17
2030 TWO DISULFIDE-REDUCING PATHWAYS ARE REQUIRED FOR THE MATURATION OF PLASTID C-TYPE CYTOCHROMES IN CHLAMYDOMONAS REINHARDTII
Das, A.; Subrahmanian, N.; Gabilly, S. T.; Andrianova, E. P.; Jouline, I.; Motohashi, K.; Hamel, P. P.
10.1101/2022.10.14.512171 — genetics — Posted on 2022-10-17
2031 A network of small RNAs regulates sporulation initiation in C. difficile
Fuchs, M.; Lamm-Schmidt, V.; Lence, T.; Sulzer, J.; Bublitz, A.; Gerovac, M.; Strowig, T.; Faber, F.
10.1101/2022.10.17.512509 — molecular biology — Posted on 2022-10-17
2032 Determinants and Mechanisms of the Low Fusogenicity and Endosomal Entry of Omicron Subvariants
Qu, P.; Evans, J. P.; Kurhade, C.; Zeng, C.; Zheng, Y.-M.; Xu, K.; Shi, P.-Y.; Xie, X.; Liu, S.-L.
10.1101/2022.10.15.512322 — microbiology — Posted on 2022-10-17
2033 A fast-killing tyrosine amide ((S)-SW228703) with blood and liver-stage antimalarial activity associated with the Cyclic Amine Resistance Locus (PfCARL)
Imlay, L. S.; Lawong, A. K.; Gahalawat, S.; Kumar, A.; Xing, C.; Mittal, N.; Wittlin, S.; Churchyard, A.; Niederstrasser, H.; Crespo-Fernandez, B.; Posner, B.; Gamo, F.-J. S.; Baum, J.; Winzeler, E.; Laleu, B.; Ready, J. M.; Phillips, M. A.
10.1101/2022.10.16.512381 — microbiology — Posted on 2022-10-17
2034 STING activation depends on ACBD3 and other phosphatidylinositol 4-phosphate-regulating proteins
Luteijn, R. D.; van Terwisga, S. R.; Ver Eecke, J. E.; Onia, L.; Zaver, S. A.; Woodward, J. J.; Raulet, D. H.; van Kuppeveld, F. J.
10.1101/2022.10.17.512580 — immunology — Posted on 2022-10-17
2038 Variability of the urinary and blood steroid profiles in healthy women
Moreillon, B.; Salamin, O.; Krumm, B.; Iannella, L.; Molaioni, F.; Kuuranne, T.; Nicoli, R.; Saugy, J.; Botre, F.; faiss, R.
10.1101/2022.10.13.511896 — physiology — Posted on 2022-10-17
2040 Inferring cell diversity in single cell data using consortium-scale epigenetic data as a biological anchor for cell identity
Sun, Y.; Shim, W. J.; Shen, S.; Sinniah, E.; Pham, D.; Su, Z.; White, M. D.; Ho, J. W. K.; Nguyen, Q.; Boden, M.; Palpant, N.
10.1101/2022.10.12.512003 — bioinformatics — Posted on 2022-10-17
2043 Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides
O'Brien, D. P.; Jones, H. B.; Guenther, F.; Murphy, E. J.; England, K. S.; Anderson, M.; Brennan, P.; Davis, J. B.; Pinto-Fernandez, A.; Turnbull, A. P.; Kessler, B. M.
10.1101/2022.09.13.507798 — biochemistry — Posted on 2022-10-17
2045 Elucidation of Global Trends in the Effects of VX-661 and VX-445 on the Expression of Clinical CFTR Variants
McKee, A. G.; McDonald, E. F.; Penn, W. D.; Kuntz, C. P.; Noguera, K.; Chamness, L. M.; Roushar, F. J.; Meiler, J.; Oliver, K. E.; Plate, L.; Schlebach, J. P.
10.1101/2022.10.14.512300 — biochemistry — Posted on 2022-10-17
2047 Phylogeographic reconstruction of the emergence and spread of Powassan virus in the northeastern United States
Vogels, C. B. F.; Brackney, D. E.; Dupuis, A. P.; Robich, R. M.; Fauver, J. R.; Brito, A. F.; Williams, S. C.; Anderson, J. F.; Lubelczyk, C. B.; Lange, R. E.; Prusinski, M. A.; Kramer, L. D.; Gangloff-Kaufmann, J. L.; Goodman, L. B.; Baele, G.; Smith, R. P.; Armstrong, P. M.; Ciota, A. T.; Dellicour, S.; Grubaugh, N. D.
10.1101/2022.10.14.512245 — genomics — Posted on 2022-10-17
2048 A climatically representative analysis of Hungarian Ixodes ricinus tick bacteriome
Toth, A. G.; Farkas, R.; Papp, M.; Haeun, Y.; Makrai, L.; Maroti, G.; Gyurkovszky, M.; Kriko, E.; Solymosi, N.
10.1101/2022.10.15.512391 — genomics — Posted on 2022-10-17
2049 Timing of TORC1 inhibition dictates Pol III involvement in longevity in Caenorhabditis elegans
Malik, Y.; Silva, I. G.; Diazgranados, R. R.; Selman, C.; Alic, N.; Tullet, J. M. A.
10.1101/2022.10.17.512483 — genetics — Posted on 2022-10-17
2050 Identification of a weight loss-associated causal eQTL in MTIF3 and the effects of MTIF3 deficiency on human adipocyte function
Huang, M.; Coral, D.; Ardalani, H.; Spegel, P.; Saadat, A.; Claussnitzer, M.; Mulder, H.; Franks, P.; Kalamajski, S.
10.1101/2022.10.16.512435 — genetics — Posted on 2022-10-17
2053 Natural selection acts on epigenetic marks
Boukas, L.; Razi, A.; Bjornsson, H. T.; Hansen, K. D.
10.1101/2020.07.04.187880 — evolutionary biology — Posted on 2022-10-17
2054 Groundfish biodiversity change in northeast Pacific waters under projected warming and deoxygenation
Thompson, P. L.; Nephin, J.; Davies, S. C.; Park, A. E.; Lyons, D. A.; Rooper, C. N.; Pena, M. A.; Christian, J. R.; Hunter, K. L.; Rubidge, E.; Holdsworth, A. M.
10.1101/2022.05.04.490690 — ecology — Posted on 2022-10-17
2056 The histone methyltransferase DOT1L regulates chromatin reorganization and gene expression during the postmeiotic differentiation of male germ cells
Blanco, M.; El Khattabi, L.; Gobe, C.; Crespo, M.; Coulee, M.; de la Iglesia, A.; Ialy-Radio, C.; Lapoujade, C.; Givelet, M.; Delessard, M.; Seller Corona, I.; Yamaguchi, K.; Vernet, N.; van Leeuwen, F.; Lermine, A.; Okada, Y.; Daveau, R.; Oliva, R.; Fouchet, P.; Ziyyat, A.; Pflieger, D.; Cocquet, J.
10.1101/2022.10.17.512530 — molecular biology — Posted on 2022-10-17
2057 A naturally occurring lytic bioprocess improves sustainability of phycocyanin production from cyanobacteria
Zorz, J.; Paquette, A. J.; Gillis, T.; Kouris, A.; Demirkaya, C.; De La Hoz Siegler, H.; Strous, M.; Vadlamani, A.
10.1101/2022.10.17.512555 — microbiology — Posted on 2022-10-17
2059 Reclassification of probiotic Lactobacillus acidophilus NCIMB 30184 as Lactobacillus helveticus and Lactobacillus casei NCIMB 30185 as Lacticaseibacillus paracasei
Rodenes, A.; Casinos Ramo, B.; Alvarez Perez, B.; Martinez Blanch, J. F.; Vijayakumar, V.; Superti, G.; Day, R.; Chenoll Cuadros, E. M.
10.1101/2022.10.17.512536 — microbiology — Posted on 2022-10-17
2061 Antiviral immune response reveals host-specific virus infections in natural ant populations
Viljakainen, L.; Fuerst, M. A.; Grasse, A. V.; Jurvansuu, J.; Oh, J.; Tolonen, L.; Eder, T.; Rattei, T.; Cremer, S.
10.1101/2022.10.17.512467 — microbiology — Posted on 2022-10-17
2063 Microbial Community Interactions on a Chip
Juang, D. S.; Wightman, W. E.; Lozano, G. L.; Barkal, L. J.; Yu, J.; Garavito, M. F.; Hurley, A.; Venturelli, O. S.; Handelsman, J.; Beebe, D. J.
10.1101/2022.10.17.511674 — microbiology — Posted on 2022-10-17
2069 Diet Induced Obesity and Diabetes Enhance Mortality and Reduces Vaccine Efficacy for SARS-CoV-2
Johnson, R.; Ardunay, J.; Hammond, H.; Logue, J.; Jackson, L.; Baracco, L.; McGrath, M.; Dillen, C.; Patel, N.; Smith, G.; Frieman, M.
10.1101/2022.10.15.512291 — microbiology — Posted on 2022-10-17
2071 MAP4Ks inhibition promotes retinal neuron regeneration from Muumlller glia in adult mice
Zhang, H.; Guo, Y.; Yang, Y.; Zhuang, J.; Wang, Y.; Zhao, J.; Zhang, R.; Hu, J.; Li, W.; Wu, J.; Xu, H.; Fliesler, S. J.; Liao, Y.; Liu, Z.
10.1101/2022.10.14.512328 — neuroscience — Posted on 2022-10-17
2076 A taxonomic revision of the genus Hydnora (Hydnoraceae)
Hatt, S.; Thorogood, C.; Bolin, J. F.; Musselman, L.; Cameron, D.; Grace, O.
10.1101/2022.10.13.512068 — plant biology — Posted on 2022-10-17
2078 DNA-encoded library (DEL)-enabled discovery of proximity-inducing small molecules
Mason, J. W.; Hudson, L.; Westphal, M. V.; Tutter, A.; Michaud, G.; Shu, W.; Ma, X.; Coley, C. W.; Clemons, P. A.; Bonazzi, S.; Berst, F.; Zecri, F. J.; Briner, K.; Schreiber, S. L.
10.1101/2022.10.13.512184 — pharmacology and toxicology — Posted on 2022-10-17
2087 Chromosome-length genome assemblies of cactophilic Drosophila illuminate links between structural and sequence evolution.
Benowitz, K. M.; Allan, C. W.; Jaworski, C. C.; Sanderson, M. J.; Diaz, F.; Chen, X.; Matzkin, L. M.
10.1101/2022.10.16.512445 — genomics — Posted on 2022-10-17
2088 The impact of the ABO/Rh blood group on susceptibility and severity among COVID-19 patients in Luanda, Angola
Sebastiao, C. S.; Teixeira, A.; Luisa, A.; Arrais, M.; Tchonhi, C.; Cogle, A.; Sacomboio, E.; Cardoso, B.; Morais, J.; Vasconcelos, J.; Brito, M.
10.1101/2022.10.14.512325 — genetics — Posted on 2022-10-17
2089 Differential Effects of Mutations of Popeye Domain Containing Proteins on Heteromeric Interaction and Membrane Trafficking
Swan, A. H.; Schindler, R. F.; Savarese, M.; Mayer, I.; Rinne, S.; Bleser, F.; Schaenzer, A.; Hahn, A.; Sabatelli, M.; Perna, F.; Chapman, K.; Pfuhl, M.; Spivey, A. C.; Decher, N.; Udd, B.; Tasca, G.; Brand, T.
10.1101/2022.10.13.511879 — genetics — Posted on 2022-10-17
2092 Targeting Epsins to Inhibit FGF Signaling while Potentiating TGF-beta Signaling Constrains Endothelial-to-Mesenchymal Transition in Atherosclerosis
Dong, Y.; Wang, B.; Du, M.; Zhu, B.; Cui, K.; Chan, S.-L.; Cowan, D. B.; Bhattacharjee, S.; Wong, S.; Bischoff, J.; Linton, M. F.; Chen, H.
10.1101/2022.08.09.503324 — cell biology — Posted on 2022-10-17
2093 A Meta-analysis of the known Global Distribution and Host Range of the Ralstonia Species Complex
Lowe-Power, T.; Avalos, J.; Bai, Y.; Charco Munoz, M.; Chipman, K.; Tom, C. E.; Williams, D.
10.1101/2020.07.13.189936 — microbiology — Posted on 2022-10-17
2094 Gaucher Disease Protects Against Tuberculosis
Fan, J.; Halre, V. L.; Lelieveld, L. T.; Whitworth, L. J.; Busch-Nentwich, E. M.; Troll, M.; Edelstein, P. H.; Cox, T. M.; Roca, F. J.; Aerts, J. M. F. G.; Ramakrishnan, L.
10.1101/2022.10.16.512394 — microbiology — Posted on 2022-10-17
2096 Clostridioides difficile PCR ribotype 151 is polyphyletic and includes pathogenic isolates from cryptic clade C-II with mono-toxin pathogenicity loci that can escape routine diagnostics
Ducarmon, Q. R.; van der Bruggen, T.; Harmanus, C.; Sanders, I. M. J. G.; Daenen, L. G. M.; Fluit, A. C.; Vossen, R. H. A. M.; Kloet, S. L.; Kuijper, E. J.; Smits, W. K.
10.1101/2022.08.17.504118 — microbiology — Posted on 2022-10-17
2097 Alcohol-sourced acetate impairs T cell function by promoting cortactin acetylation
Azizov, V.; Frech, M.; Huebner, M.; Hofmann, J.; Kubankova, M.; Lapuente, D.; Tenbusch, M.; Guck, J.; Schett, G.; Zaiss, M. M.
10.1101/2022.03.08.483253 — immunology — Posted on 2022-10-17
2098 Kupffer cells dictate hepatic responses to the atherogenic dyslipidemic insult
Hellberg, S.; Ahmed, O.; Zhang, Y.; Di Nunzio, G.; Bjorck, H. M.; Francis, R.; Fagerberg, L.; Gistera, A.; Zhang, X.; Metso, J.; Manfe, V.; Soto, Y.; Franco-Cereceda, A.; Eriksson, P.; Jauhiainen, M.; Olofsson, P. S.; Malin, S. G.
10.1101/2022.10.13.512086 — immunology — Posted on 2022-10-17
2099 MLKL deficiency protects against low-grade, sterile inflammation in aged mice
Tovey, E. C.; Garnish, S. E.; Day, J.; Anderton, H.; Chiou, S.; Hempel, A.; Hall, C.; Patel, K.; Gangatirkar, P.; Li Wai Suen, C. S. N.; Garnham, A.; Kueh, A. J.; Nachbur, U.; Samson, A. L.; Murphy, J. M.; Hildebrand, J. M.
10.1101/2022.10.17.512454 — immunology — Posted on 2022-10-17
2104 Chromosome-level genome assembly of Euphorbia peplus, a model system for plant latex, reveals that relative lack of Ty3 transposons contributed to its small genome size
Johnson, A. R.; Yue, Y.; Carey, S. B.; Park, S. J.; Kruse, L. H.; Harkess, A.; Bao, A.; Pasha, A.; Provart, N. J.; Moghe, G. D. J.; Frank, M.
10.1101/2022.10.13.512124 — plant biology — Posted on 2022-10-17
2105 Chemical inhibition of PIN auxin transporters by the anti-inflammatory drug Naproxen
Xia, J.; Kong, M.; Yang, Z.; Sun, L.; Peng, Y.; Wei, H.; Ying, W.; Gao, Y.; Friml, J.; Liu, X.; Sun, L.; Tan, S.
10.1101/2022.10.13.512040 — plant biology — Posted on 2022-10-17
2106 PHYTOCHROME C regulation of PHOTOPERIOD1 is mediated by EARLY FLOWERING 3 in Brachypodium distachyon
Woods, D. P.; Li, W.; Sibout, R.; Shao, M.; Laudencia-Chingcuanco, D.; Vogel, J.; Dubcovsky, J.; Amasino, R.
10.1101/2022.10.11.511813 — plant biology — Posted on 2022-10-17
2107 Leak current, even with gigaohm seals, can cause misinterpretation of stem cell-derived cardiomyocyte action potential recordings
Clark, A. P.; Clerx, M.; Wei, S.; Lei, C. L.; de Boer, T.; Mirams, G. R.; Christini, D. J.; Krogh-Madsen, T.
10.1101/2022.10.13.511949 — physiology — Posted on 2022-10-17
2108 NAD metabolism modulates inflammation and mitochondria function in diabetic kidney disease
Myakala, K.; Wang, X.; Shults, N. V.; Jones, B. A.; Yang, X.; Rosenberg, A. Z.; Ginley, B.; Sarder, P.; Brodsky, L.; Jang, Y.; Na, C. H.; Chi, Y.; Zhang, X.; Guha, U.; Wu, C.; Bansal, S.; Ma, J.; Cheema, A.; Albanese, C.; Hirschey, M. D.; Yoshida, T.; Kopp, J. B.; Panov, J.; Levi, M.
10.1101/2021.12.05.471273 — pathology — Posted on 2022-10-17
2109 Key Genetic Determinants Driving Esophageal Squamous Cell Carcinoma Initiation and Immune Evasion
Ko, K.-P.; Huang, Y.; Zhang, S.; Zou, G.; Kim, B.; Zhang, J.; Jun, S.; Martin, C.; Dunbar, K. J.; Efe, G.; Rustgi, A. K.; Nakagawa, H.; Park, J.-I.
10.1101/2022.10.13.512143 — cancer biology — Posted on 2022-10-17
2111 Characterizing the conformational free-energy landscape of RNA stem-loops using single-molecule field-effect transistors
Jang, S. S.; Dubnik, S.; Hon, J.; Hellenkamp, B.; Lynall, D. G.; Shepard, K. L.; Nuckolls, C.; Gonzalez, R. L.
10.1101/2022.01.13.475405 — biophysics — Posted on 2022-10-17
2114 Refphase: Multi-sample reference phasing reveals haplotype-specific copy number heterogeneity
Watkins, T. B.; Colliver, E. C.; Huska, M. R.; Kaufmann, T. L.; Lim, E. L.; Haase, K.; Van Loo, P.; Swanton, C.; McGranahan, N.; Schwarz, R. F.
10.1101/2022.10.13.511885 — bioinformatics — Posted on 2022-10-17
2115 Arctic humpback whales respond to nutritional opportunities before migration
Kettemer, L. E.; Ramm, T.; Broms, F.; Biuw, M.; Blanchet, M.-A.; Bourgeon, S.; Dubourg, P.; Ellendersen, A. C. J.; Horaud, M.; Kershaw, J.; Miller, P. J. O.; Oien, N.; Pallin, L. J.; Rikardsen, A. H.
10.1101/2022.10.13.511409 — animal behavior and cognition — Posted on 2022-10-17
2117 Modeling the evolutionary history of nonclassical monocytes in mammals
Araujo, D. J.; Fernandez, D.; Alimadadi, A.; Zagal-Norman, A.; Hedrick, C. C.
10.1101/2022.10.12.511958 — evolutionary biology — Posted on 2022-10-17
2119 Effects of ancient anthropogenic clam gardens on the growth, survival, and transcriptome of Pacific littleneck clams (Leukoma staminea)
Raap, M. R.; Gurney-Smith, H. J.; Dudas, S. E.; Pearce, C. M.; Leong, J. S.; Sutherland, B. J. G.; Koop, B. F.
10.1101/2022.09.09.507365 — ecology — Posted on 2022-10-17
2120 Maternal omega-3 fatty acid deficiency affects fetal thermogenic development and postnatal musculoskeletal growth in mice
Srinivas, V.; Molangiri, A.; Varma, S.; Mallepogu, A.; Kona, S. R.; Ibrahim, A.; Duttaroy, A. K.; Basak, S.
10.1101/2022.10.13.512191 — developmental biology — Posted on 2022-10-17
2123 Type 2 Inflammation Drives an Airway Basal Stem Cell Program Through Insulin Receptor Substrate Signaling
Wang, X.; Hallen, N.; Lee, M.; Samuchiwal, S.; Ye, Q.; Buchheit, K.; Maxfield, A.; Roditi, R.; Bergmark, R.; Bhattacharyya, N.; Ryan, T.; Gakpo, D.; Raychaudhuri, S.; Dwyer, D.; Laidlaw, T. M.; Boyce, J. A.; Gutierrez-Arcelus, M.; Barrett, N.
10.1101/2022.10.13.512129 — immunology — Posted on 2022-10-17
2124 Single-cell Landscape Analysis of the Circulating Human B Cell Pool under Selective Pressure of Allogeneic Stem Cell Transplantation
Poe, J. C.; Fang, J.; Zhang, D.; Lee, M. R.; DiCioccio, R. A.; Su, H.; Qin, X.; Zhang, J.; Visentin, J.; Bracken, S. J.; Ho, V. T.; Wang, K. S.; Rose, J. J.; Pavletic, S. Z.; Hakim, F. T.; Jia, W.; Riley, L. S.; Suthers, A. N.; Curry-Chisolm, I.; Horwitz, M. E.; Rizzieri, D. A.; McManigle, W.; Chao, N. J.; Cardones, A. R.; Xie, J.; Owzar, K.; Sarantopoulos, S.
10.1101/2022.10.13.512162 — immunology — Posted on 2022-10-17
2126 An Abundance of Free Proteasomal Regulatory (19S) Particles Regulate Neuronal Synapses Independent of the Proteasome
Sun, C.; Desch, K.; Nassim-Assir, B.; Giandomenico, S. L.; Nemcova, P.; Langer, J. D.; Schuman, E. M.
10.1101/2022.10.17.512557 — neuroscience — Posted on 2022-10-17
2129 NeuroWRAP: integrating, validating, and sharing neurodata analysis workflows
Bowen, Z.; Magnusson, G.; Diep, M.; Ayyangar, U.; Smirnov, A.; Losert, W.
10.1101/2022.10.13.511794 — neuroscience — Posted on 2022-10-17
2130 Multi-view manifold learning of human brain statetrajectories
Busch, E. L.; Huang, J.; Benz, A.; Wallenstein, T.; Lajoie, G.; Wolf, G.; Krishnaswamy, S.; Turk-Browne, N. B.
10.1101/2022.05.03.490534 — neuroscience — Posted on 2022-10-17
2132 Computational Speed-Up of Large-Scale, Single-Cell Model Simulations Via a Fully-Integrated SBML-Based Format
Mutsuddy, A.; Erdem, C.; Huggins, J. R.; Salim, M.; Cook, D.; Hobbs, N.; Feltus, F. A.; Birtwistle, M. R.
10.1101/2022.10.13.511603 — systems biology — Posted on 2022-10-17
2137 A chromosome-scale assembly of Brassica carinata (BBCC) accession HC20 containing resistance to multiple pathogens and an early generation assessment of introgressions into B. juncea (AABB)
Paritosh, K.; Rajarammohan, S.; Yadava, S. K.; Sharma, S.; Verma, R.; Mathur, S.; Mukhopadhyay, A.; Gupta, V.; Pradhan, A. K.; Kaur, J.; Pental, D.
10.1101/2022.10.13.512038 — plant biology — Posted on 2022-10-17
2142 Intermittent hypoxia therapy engages multiple longevity pathways to double lifespan in C.elegans
Pitt, J. N.; Chavez, E.; Provencher, K. M.; Chen, M.; Tran, C.; Tran, J.; Huang, K.; Vaid, A.; Abadir, M. L.; Arang, N.; Leiser, S. F.; Roth, M. B.; Kaeberlein, M.
10.1101/2022.10.13.512140 — physiology — Posted on 2022-10-17
2143 Endothelial FABP4 constitutes the majority of basal circulating hormone levels and regulates lipolysis-driven insulin secretion
Inouye, K. E.; Prentice, K. J.; Lee, A.; Dominguez-Gonzalez, C.; Chen, M. X.; Lee, G. Y.; Hotamisligil, G. S.
10.1101/2022.10.13.511807 — physiology — Posted on 2022-10-17
2146 Selection of the Early Genetic Code by Ultraviolet Light
Kufner, C. L.; Krebs, S. B.; Fischaleck, M.; Philippou-Massier, J.; Blum, H.; Bucher, D. B.; Braun, D.; Zinth, W.; Mast, C. B.
10.1101/2022.10.13.512048 — biophysics — Posted on 2022-10-17
2147 MSFragger-Labile: A Flexible Method to Improve Labile PTM Analysis in Proteomics
Polasky, D. A.; Geiszler, D. J.; Yu, F.; Li, K.; Teo, G. C.; Nesvizhskii, A. I.
10.1101/2022.10.12.511963 — bioinformatics — Posted on 2022-10-17
2153 Declining autozygosity over time: an exploration in over 1 million individuals from three diverse cohorts
Colbert, S. M.; Wendt, F. R.; Pathak, G.; Helmer, D. A.; Hauser, E.; Keller, M. C.; Polimanti, R.; Johnson, E. C.
10.1101/2022.10.13.512166 — genomics — Posted on 2022-10-17
2160 Environmental drivers of earthworm communities along an altitudinal gradient in the French Alps
gabriac, Q.; Ganault, P.; Barois, I.; Aranda-Delgado, E.; Cimetiere, E.; Cortet, J.; Gautier, M.; Hedde, M.; Marchan, D. F.; Pimentel Reyes, J. C.; Stokes, A.; Decaens, T.
10.1101/2022.10.13.512055 — ecology — Posted on 2022-10-17
2162 Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation
Ahmed, F.; Vu, L. T.; Zhu, H.; Iu, D. S. H.; Fogarty, E. A.; Kwak, Y.; Chen, W.; Franconi, C. J.; Munn, P. R.; Levine, S. M.; Stevens, J.; Mao, X.; Shungu, D. C.; Moore, G. E.; Keller, B. A.; Hanson, M. R.; Grenier, J. K.; Grimson, A.
10.1101/2022.10.13.512091 — immunology — Posted on 2022-10-17
2163 TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice
Wang, Y.; Wu, T.; Tsai, M.-C.; Rezzonico, M. G.; Abdel-Haleem, A. M.; Xie, L.; Gandham, V. D.; Ngu, H.; Stark, K.; Glock, C.; Xu, D.; Foreman, O.; Friedman, B. A.; Sheng, M.; Hanson, J. E.
10.1101/2022.10.13.512193 — neuroscience — Posted on 2022-10-17
2164 MIND Networks: Robust Estimation of Structural Similarity from Brain MRI
Sebenius, I.; Seidlitz, J.; Warrier, V.; Bethlehem, R. A. I.; Alexander-Bloch, A.; Mallard, T.; Romero Garcia, R.; Bullmore, E. T.; Morgan, S. E.
10.1101/2022.10.12.511922 — neuroscience — Posted on 2022-10-17
2165 Decoding Fear or Safety and Approach or Avoidance by Brain-Wide Network Dynamics
Marques, D. B.; Rossignoli, M. T.; Mesquita, B. d. A.; Prizon, T.; Zacharias, L. R.; Ruggiero, R. N.; Leite, J. P.
10.1101/2022.10.13.511989 — neuroscience — Posted on 2022-10-17
2167 Reflective multi-immersion microscope objectives inspired by the Schmidt telescope
Voigt, F.; Reuss, A. M.; Naert, T.; Hildebrand, S.; Hotz, A. L.; Whitehead, L.; Bahl, A.; Neuhauss, S. C. F.; Roebroeck, A.; Stoeckli, E. T.; Lienkamp, S. S.; Aguzzi, A.; Helmchen, F.
10.1101/2022.10.13.511906 — neuroscience — Posted on 2022-10-17
2168 Widespread coding of navigational variables in prefrontal cortex
Maisson, D.; Voloh, B.; Lopez Cervera, R.; Conover, I.; Zambre, M.; Zimmermann, J.; Hayden, B. Y.
10.1101/2022.10.13.512139 — neuroscience — Posted on 2022-10-17
2170 Smaller total and subregional cerebellar volumes in posttraumatic stress disorder: a mega-analysis by the ENIGMA-PGC PTSD workgroup
Huggins, A. A.; Baird, C. L.; Briggs, M.; Laskowitz, S.; Fouda, S.; Haswell, C. C.; Sun, D.; Salminen, L. E.; Jahanshad, N.; Thomopoulos, S. I.; Veltman, D. J.; Frijling, J. L.; Olff, M.; van Zuiden, M.; Koch, S. B. J.; Nawijn, L.; Wang, L.; Zhu, Y.; Li, G.; Stein, D. J.; Ipser, J.; Seedat, S.; du Plessis, S.; van den Heuvel, L. L.; Suarez-Jimenez, B.; Zhu, X.; Kim, Y.; He, X.; Zilcha-Mano, S.; Lazarov, A.; Neria, Y.; Stevens, J. S.; Ressler, K. J.; Jovanovic, T.; van Rooij, S. J. H.; Fani, N.; Hudson, A. R.; Mueller, S. C.; Sierk, A.; Manthey, A.; Walter, H.; Daniels, J. K.; Schmahl, C.; Herz
10.1101/2022.10.13.512111 — neuroscience — Posted on 2022-10-17
2171 Neurofeedback training can modulate task-relevant memory replay in rats
Gillespie, A. K.; Astudillo Maya, D. A.; Denovellis, E. L.; Desse, S.; Frank, L. M.
10.1101/2022.10.13.512183 — neuroscience — Posted on 2022-10-17
2174 Knowledge Mapping of Alternative Splicing of Cancer From 2012 to 2021: A Bibliometric Analysis
Tian, B.; Bian, Y.; Bian, D.-J.; Gao, Y.; Zhang, X.; Zhou, S.-W.; Zhang, Y.-H.; Pang, Y.-N.; Li, Z.-S.; Wang, L.-W.
10.1101/2022.10.12.511996 — cancer biology — Posted on 2022-10-17
2182 Disparate patterns of genetic divergence in three widespread corals across a pan-Pacific environmental gradient highlights species-specific adaptation trajectories.
Hume, B. C.; Voolstra, C. R.; Armstrong, E.; Mitushasi, G.; Porro, B.; Oury, N.; Agostini, S.; Boissin, E.; Poulain, J.; Carradec, Q.; Paz-Garcia, D. A.; Zoccola, D.; Magalon, H.; Moulin, C.; Bourdin, G.; Iwankow, G.; Romac, S.; Banaigs, B.; Boss, E.; Bowler, C.; de Vargas, C.; Douville, E.; Flores, M.; Furla, P.; Galand, P.; Gilson, E.; Lombard, F.; Pesant, S.; Reynaud, S.; Sullivan, M. B.; Shinichi, S.; Thomas, O.; Trouble, R.; Vega Thurber, R.; Wincker, P.; Planes, S.; Allemand, D.; Forcioli, D.
10.1101/2022.10.13.512013 — genetics — Posted on 2022-10-17
2183 Non-triplet genetic code in ciliate Euplotes ciliates is a result of neutral evolution
Gaydukova, S. A.; Moldovan, M. A.; Vallesi, A.; Heaphy, S.; Atkins, J. F.; Gelfand, M. S.; Baranov, P.
10.1101/2022.10.12.511967 — evolutionary biology — Posted on 2022-10-17
2184 Not just with the natives, but phylogenetic relationship between stages of the invasion process determines invasion success of alien plant species
Banerjee, A. K.; Hui, F.; Liang, X.; Tan, F.; Wang, J.; Lin, Y.; Yin, M.; Peng, H.; Guo, W.; Zhang, N.; Huang, Y.
10.1101/2022.10.12.512006 — ecology — Posted on 2022-10-17
2189 Inulin prebiotic reinforces host cancer immunosurveillance via γδ T cell activation
Boucher, E.; Plazy, C.; Richard, M. L.; Suau, A.; Mangin, I.; Cornet, M.; Aldebert, D.; Toussaint, B.; Hannani, D.
10.1101/2022.10.13.512019 — immunology — Posted on 2022-10-17
2190 Development of an affinity-enhanced clinical candidate TCR targeting NY-ESO-1 with optimal potency and high specificity
Ou, Y.; Liu, M.; Zhan, K.; Wu, W.; Huang, J.; Sun, H.; Zheng, H.; Yu, X.; Gong, H.; Han, Z.; Chen, A.; Liao, Y.; Lin, Y.; Liu, G.; Liu, Q.; Ma, R.; Mei, Y.; Tang, X.; Weng, Z.; Wu, J.; Ye, Y.; Zhang, T.; Chen, J.; Chen, L.; Ding, Q.; Fan, H.; Hu, J.; Huang, J.; Huang, L.; Li, Q.; Li, S.; Liu, M.; Shi, J.; Tan, X.; Wang, X.; Xiang, R.; Yan, Q.; Zhang, J.; Zheng, W.; Zhong, S.
10.1101/2022.10.12.511904 — immunology — Posted on 2022-10-17
2192 Elucidating a locus coeruleus-hippocampal dopamine pathway for operant reinforcement
Petter, E. A.; Fallon, I. P.; Hughes, R. N.; Watson, G.; Meck, W.; Ulloa Severino, F. P.; Yin, H. H.
10.1101/2022.10.13.512041 — neuroscience — Posted on 2022-10-17
2193 Early impairments of visually-driven neuronal ensemble dynamics in the rTg4510 tauopathy mouse model
Parka, A.; Degel, C.; Dreyer, J.; Richter, U.; Hall, B.; Bastlund, J. F.; Laursen, B.; Nedergaard, M.; Sotty, F.; Botta, P.
10.1101/2022.10.13.512017 — neuroscience — Posted on 2022-10-17
2194 Presymptomatic neuroanatomical and cognitive biomarkers of alpha-synuclein propagation in a mouse model of synucleinopathy
Tullo, S.; Miranda, A. S.; del Cid-Pellitero, E.; Peng Lim, M.; Gallino, D.; Attaran, A.; Patel, R.; Novikov, V.; Park, M.; Beraldo, F.; Luo, W.; Shlaifer, I.; Durcan, T. M.; Bussey, T. J.; Saksida, L. M.; Fon, E. A.; Prado, V. F.; Prado, M. A. M.; Chakravarty, M. M.
10.1101/2022.10.12.511820 — neuroscience — Posted on 2022-10-17
2196 Physiological Condition Dependent Changes in Ciliary GPCR Localization in the Brain
Brewer, K. M.; Engle, S. E.; Bansal, R.; Brewer, K. K.; Jasso, K. R.; McIntyre, J. C.; Vaisse, C.; Reiter, J. F.; Berbari, N. F.
10.1101/2022.10.13.512090 — neuroscience — Posted on 2022-10-17
2197 Leak current, even with gigaohm seals, can cause misinterpretation of stem-cell derived cardiomyocyte action potential recordings
Clark, A. P.; Clerx, M.; Wei, S.; Lei, C. L.; de Boer, T.; Mirams, G. R.; Christini, D. J.; Krogh-Madsen, T.
10.1101/2022.10.13.511949 — physiology — Posted on 2022-10-17
2198 miR-495-3p Sensitizes BCR::ABL1 Expressing Leukemic cells to Tyrosine Kinase Inhibitors by Targeting Multidrug Resistance 1 Gene including in T315I Mutated cells
Rittavee, Y.; Artus, J.; Desterke, C.; Simanic, I.; Eduardo Botelho de Souza, L.; Riccaldi, S.; Coignard, S.; Ijjeh, Y.; Hugues, P.; Bennaceur Griscelli, A.; Turhan, A. G.; Foudi, A.
10.1101/2022.10.17.512501 — cancer biology — Posted on 2022-10-17
2199 FGFR1 governs iron metabolism via regulating post-translational modification of IRP2 in prostate cancer cells
Wang, C.; Lin, H.; Li, X.; Wang, F.; Shi, L.; Zhou, D.; Chen, S.; He, P.; Zheng, X.; Qiu, F.; Yuan, Y.; Lin, S.
10.1101/2022.10.17.512481 — cancer biology — Posted on 2022-10-17
2200 Metabolic clogging of mannose triggers genomic instability via dNTP loss in human cancer cells
Harada, Y.; Mizote, Y.; Suzuki, T.; Nishida, M.; Hiratsuka, T.; Ueda, A.; Imagawa, Y.; Maeda, K.; Ohkawa, Y.; Murai, J.; Freeze, H. H.; Miyoshi, E.; Higashiyama, S.; Udono, H.; Dohmae, N.; Tahara, H.; Taniguchi, N.
10.1101/2022.10.17.512485 — cancer biology — Posted on 2022-10-17
2201 Comprehensive single-cell transcriptomic analysis of embryonic melanoblasts uncovers lineage-specific mechanisms of melanoma metastasis and therapy resistance
Gopalan, V.; Day, C.-P.; Perez-Guijarro, E.; Chin, S.; Ebersole, J.; Smith, C.; Simpson, M.; Sassano, A.; Alves Constantino, M.; Wu, E.; Yang, H. H.; Lee, M. P.; Hannenhalli, S.; Merlino, G.; Marie, K. L.
10.1101/2022.10.14.512297 — cancer biology — Posted on 2022-10-17
2206 The Golgi complex is a regulatory hub for homologous recombination-mediated DNA repair.
Galea, G.; Kuodyte, K.; Khan, M. M.; Thul, P. J.; Neumann, B.; Lundberg, E.; Pepperkok, R.
10.1101/2022.10.17.512236 — cell biology — Posted on 2022-10-17
2207 Proteomic profiling reveals lysosomal heterogeneity in association with longevity
Yu, Y.; Gao, S. M.; Guan, Y.; Hu, P.; Zhang, Q.; Liu, J.; Jing, B.; Zhao, Q.; Sabatini, D. M.; Abu-Remaileh, M.; Jung, S. Y.; Wang, M. C.
10.1101/2022.10.16.512400 — cell biology — Posted on 2022-10-17
2208 Gaq-PKD/PKCμ regulates the IkB transcription to limit the NF-kB mediated inflammatory response essential for early pregnancy
Jiang, Y.; He, Y.; Liu, S.; Li, G.; Chen, D.; Deng, W.; Li, P.; Zhang, Y.; Wu, J.; Li, J.; Wang, L.; Lin, J.; Wang, H.; Kong, S.; Shi, G.
10.1101/2022.10.17.512513 — cell biology — Posted on 2022-10-17
2209 The ER tether VAPA is required for proper cell motility and for anchoring ER-plasma membrane contact sites to focal adhesions
Siegfried, H.; Le Borgne, R.; Durieu, C.; De Azevedo Laplace, T.; Verraes, A.; Daunas, L.; Verbavatz, J.-M.; Heuze, M. L.
10.1101/2022.10.17.512434 — cell biology — Posted on 2022-10-17
2212 Decoding of YAP levels and dynamics by pluripotency factors
Meyer, K.; Lammers, N. C.; Bugaj, L. J.; Garcia, H. H.; Weiner, O. D.
10.1101/2022.10.17.512504 — cell biology — Posted on 2022-10-17
2213 Single-cell analysis reveals inter- and intratumour heterogeneity in metastatic breast cancer
Hamelin, B.; Obradovic, M. M. S.; Sethi, A.; Koch, M.; Muenst, S.; Beisel, C.; Eschbach, K.; Kohler, H.; Soysal, S.; Vetter, M.; Weber, W. P.; Stadler, M.; Bentires-Alj, M.
10.1101/2022.10.16.512415 — cancer biology — Posted on 2022-10-17
2215 Class IIa HDACs reprogram mitochondrial metabolism to inhibit apoptosis and ferroptosis in response to lipotoxicity
Martin, S. D.; Connor, T.; Sanigorski, A.; McEwen, K. A.; Henstridge, D. C.; Nijagal, B.; De Souza, D. P.; Tull, D.; Meikle, P.; Kowalski, G. M.; Bruce, C.; Gregorevic, P.; Febbraio, M.; Collier, F.; Walder, K. R.; McGee, S.
10.1101/2022.10.17.512492 — cell biology — Posted on 2022-10-17
2216 Rapid and High Resolution Ambient Temperature Structure Determination at Turkish Light Source
Gul, M.; Ayan, E.; Destan, E.; Johnson, J. A.; Shafiei, A.; Kepceoglu, A.; Yilmaz, M.; Ertem, F. B.; Yapici, I.; Tosun, B.; Baldir, N.; Tokay, N.; Nergiz, Z.; Karakadioglu, G.; Paydos, S. S.; Kulakman, C.; Ferah, C. K.; Guven, O.; Atalay, N.; Akcan, E. K.; Cetinok, H.; Arslan, N. E.; Sabanoglu, K.; Asci, B.; Tavli, S.; Altuntas, S.; Otsuka, M.; Fujita, M.; Tekin, S.; Ciftci, H.; Durdagi, S.; Karaca, E.; Kaplan Turkoz, B.; Kabasakal, B. V.; Kati, A.; DeMirci, H.
10.1101/2022.10.12.511637 — biophysics — Posted on 2022-10-17
2217 Loss of N-terminal acetyltransferase A activity induces thermally unstable ribosomal proteins and increases their turnover
Guzman, U. H.; Aksnes, H.; Ree, R.; Krogh, N.; Jakobsson, M. E.; Jensen, L. J.; Arnesen, T. E.; Olsen, J. V.
10.1101/2022.10.17.512508 — biochemistry — Posted on 2022-10-17
2223 Direct Brain Recordings Identify a Causal Subsequent-Memory Effect
Rubinstein, D. Y.; Weidemann, C. T.; Sperling, M. R.; Kahana, M. J.
10.1101/2022.10.12.511606 — neuroscience — Posted on 2022-10-17
2225 Natural variability in bee brain size and symmetry revealed by micro-CT imaging and deep learning
Lösel, P. D.; Monchanin, C.; Lebrun, R.; Jayme, A.; Relle, J.; Devaud, J.-M.; Heuveline, V.; Lihoreau, M.
10.1101/2022.10.12.511944 — animal behavior and cognition — Posted on 2022-10-17
2229 Prefrontal norepinephrine represents a threat prediction error under uncertainty
Basu, A.; Yang, J.-h.; Yu, A. L.; Glaeser-Khan, S.; Feng, J.; Krystal, J. H.; Li, Y.; Kaye, A. P.
10.1101/2022.10.13.511463 — neuroscience — Posted on 2022-10-17
2231 Aspergillus fumigatus can display persistence to the fungicidal drug voriconazole
Scott, J.; Valero, C.; Mato-Lopez, A.; Donaldson, I. J.; Roldan, A.; Chown, H.; Van-Rhijn, N.; Lobo-Vega, R.; Gago, S.; Furukawa, T.; Morogovsky, A.; Ben Ami, R.; Bowyer, P.; Osherov, N.; Fontaine, T.; Goldman, G. H.; Mellado, E.; Bromley, M.; Amich, J.
10.1101/2022.05.16.491816 — microbiology — Posted on 2022-10-17
2235 The integrity of dopaminergic and noradrenergic brain regions is associated with different aspects of late-life memory performance
Dahl, M. J.; Bachman, S. L.; Dutt, S.; Duezel, S.; Bodammer, N. C.; Lindenberger, U.; Kuehn, S.; Werkle-Bergner, M.; Mather, M.
10.1101/2022.10.12.511748 — neuroscience — Posted on 2022-10-17
2238 Human organoid model of PCH2a recapitulates brain region-specific pathology
Kagermeier, T.; Hauser, S.; Sarieva, K.; Laugwitz, L.; Groeschel, S.; Janzarik, W.; Yentuer, Z.; Becker, K.; Schoels, L.; Kraegeloh-Mann, I.; Mayer, S.
10.1101/2022.10.13.512020 — neuroscience — Posted on 2022-10-17
2239 Multi-omic profiling of the developing human cerebral cortex at the single cell level
Zhu, K.; Bendl, J.; Rahman, S.; Vicari, J. M.; Coleman, C.; Clarence, T.; Latouche, O.; Tsankova, N. M.; Li, A.; Brennand, K. J.; Lee, D.; Yuan, G.; Fullard, J. F.; Roussos, P.
10.1101/2022.10.14.512250 — neuroscience — Posted on 2022-10-17
2240 A human DCC variant causing mirror movement disorder reveals an essential role for the Wave regulatory complex in Netrin/DCC signaling
Chaudhari, K.; Zhang, K.; Yam, P. T.; Zang, Y.; Kramer, D. A.; Schlienger, S.; Calabretta, S.; Collins, M.; Srour, M.; Chen, B.; Charron, F.; Bashaw, G. J.
10.1101/2022.10.13.511954 — neuroscience — Posted on 2022-10-17
2241 Rapid polygenic adaptation in a wild population of ash trees under a novel fungal epidemic
Metheringham, C. L.; Plumb, W.; Stocks, J.; Kelly, L.; Nemesio Gorriz, M.; Moat, J.; Buggs, R.; Nichols, R. A.
10.1101/2022.08.01.502033 — evolutionary biology — Posted on 2022-10-17
2247 Tubulin engineering by semisynthesis reveals that polyglutamylation directs detyrosination
Ebberink, E.; Fernandes, S.; Hatzopoulos, G.; Agashe, N.; Guidotti, N.; Reichart, T. M.; Reymond, L.; Velluz, M. C.; Pourroy, C.; Janke, C.; Gonczy, P.; Fierz, B.; Aumeier, C.
10.1101/2022.09.20.508649 — biochemistry — Posted on 2022-10-17
2248 Data driven model discovery and interpretation for CAR T-cell killing using sparse identification and latent variables
Brummer, A. B.; Xella, A.; Woodall, R.; Adhikarla, V.; Cho, H.; Gutova, M. B.; Brown, C. E.; Rockne, R. C.
10.1101/2022.09.22.508748 — cancer biology — Posted on 2022-10-16
2249 Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes.
Zhang, X.; Li, Z.; Zhang, Y.; Liu, Y.; Wang, J.; Liu, B.; Chen, Q.; Wang, Q.; Fu, L.; Wang, P.; Zhong, X.; Jin, L.; Chen, L.; He, J.; Zhao, J.; Xiong, X.
10.1101/2022.10.14.512296 — biochemistry — Posted on 2022-10-16
2250 SARS-CoV-2 multi-antigen protein microarray for detailed characterization of antibody responses in COVID-19 patients
Celikgil, A.; Massimi, A. B.; Nakouzi, A.; Herrera, N. G.; Morano, N. C.; Lee, J. H.; Yoon, H. a.; Garforth, S. J.; Almo, S. C.
10.1101/2022.10.14.512324 — biochemistry — Posted on 2022-10-16
2251 The contribution of sex chromosome conflict to disrupted spermatogenesis in hybrid house mice
Kopania, E. E. K.; Watson, E. M.; Rathje, C. C.; Skinner, B. M.; Ellis, P. J.; Larson, E. L.; Good, J. M.
10.1101/2022.07.19.499960 — evolutionary biology — Posted on 2022-10-16
2255 Legionella para-effectors target chromatin and promote bacterial replication
Schator, D.; Mondino, S.; Berthelet, J.; Di Silvestre, C.; Ben Asssya, M.; Rusniok, C.; Rodreigues-Lima, F.; Wehenkel, A. M.; Buchrieser, C.; Rolando, M.
10.1101/2022.10.16.512414 — microbiology — Posted on 2022-10-16
2256 Transcriptomics in serum and culture medium reveal shared and differential gene regulation in pathogenic and commensal Streptococcus suis
Fredriksen, S.; Ruijten, S. D. E.; Murray, G. G. R.; Juanpere-Borras, M.; van Baarlen, P.; Boekhorst, J.; Wells, J. M.
10.1101/2022.10.16.512421 — microbiology — Posted on 2022-10-16
2257 Humanized V(D)J-rearranging and TdT-expressing Mouse Vaccine Models with Physiological HIV-1 Broadly Neutralizing Antibody Precursors
Luo, S.; Jing, C.; Ye, A. Y.; Kratochvil, S.; Cottrell, C. A.; Koo, J.-H.; Williams, A. C.; Francisco, L. V.; Batra, H.; Lamperti, E.; Kalyuzhniy, O.; Zhang, Y.; Barbieri, A.; Manis, J. P.; Haynes, B. F.; Schief, W. R.; Batista, F. D.; Tian, M.; Alt, F. W.
10.1101/2022.10.12.511911 — immunology — Posted on 2022-10-16
2258 Early immunomodulatory program triggered by pro-tolerogenic Bifidobacterium pseudolongum drives cardiac transplant outcomes
Gavzy, S. J.; Kensiski, A.; Saxena, V.; Lakhan, R.; Hittle, L.; Iyyathurai, J.; Wu, L.; Dhakal, H.; Lee, Z. L.; Li, L.; Lee, Y.; Zhang, T.; Lwin, H. W.; Shirkey, M. W.; Paluskievicz, C.; Piao, W.; Mongodin, E. F.; Ma, B.; Bromberg, J. S.
10.1101/2022.10.13.511915 — immunology — Posted on 2022-10-16
2261 A wide foodomics approach coupled with metagenomics elucidates the environmental signature of Protected Geographical Indication potatoes
Boutsika, A.; Michailidis, M.; Moysiadis, T.; Dalakouras, A.; Skodra, C.; Xanthopoulou, A.; Stamatakis, G.; Samiotaki, M.; Tanou, G.; Ganopoulou, M.; Angelis, L.; Bazakos, C.; Molassiotis, A.; Nianiou-Obeidat, I.; Mellidou, I.; Ganopoulos, I.
10.1101/2022.10.12.511727 — plant biology — Posted on 2022-10-16
2262 A drug's most potent target is not necessarily the source of its anti-cancer activity
Bhattacharjee, D.; Bakar, J.; Sausville, E. L.; Mendelson, B. E.; Long, K.; Smith, J. C.; Sheltzer, J. M.
10.1101/2022.10.16.512438 — cancer biology — Posted on 2022-10-16
2264 Flexible IrOx Neural Electrode for Mouse Vagus Nerve Stimulation
Sun, T.; Tsaava, T.; Peragine, J.; Crosfield, C.; Lopez, M. F.; Modi, R.; Sharma, R.; Li, C.; Sohal, H.; Chang, E. H.; Rieth, L.
10.1101/2022.10.12.511950 — bioengineering — Posted on 2022-10-16
2265 An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function
Cuesta, N.; Contreras, J. M.; Sanchez-Waldermer, J.; Soriano-Maldonado, P.; Martin-Hurtado, A.; Munoz, I. M.; Llimargas, M.; Munoz, J.; Plaza-Menacho, I.
10.1101/2022.10.16.512342 — biochemistry — Posted on 2022-10-16
2266 Genetic and histological correlation between the musk gland and skin of Chinese forest musk deer
Dong, W.; Li, L.; Cao, H.; Yang, J.; Jin, T.; Ma, Y.; Chen, Y.; Wang, Y.; Li, Z.; Gao, H.; Zhu, C.; Yang, T.; Deng, Y.; Yang, F.
10.1101/2022.10.15.512364 — biochemistry — Posted on 2022-10-16
2267 Functional characterization of a PHF8 processed pseudogene in the mouse genome
St-Germain, J.; Khan, M. R.; Bavykina, V.; Desmarais, R.; Scott, M.; Boissonneault, G.; Brunet, M. A.; Laurent, B.
10.1101/2022.10.16.512440 — biochemistry — Posted on 2022-10-16
2268 Thymic mesenchymal niche cells drive T cell immune regeneration
Gustafsson, K.; Isaev, S.; Kooshesh, K. A.; Baryawno, N.; Kokkaliaris, K. D.; Severe, N.; Zhao, T.; Scadden, E. W.; Spencer, J. A.; Burns, C.; Akilan, K.; Barkas, N.; Gessessew, H.; Lin, C. P.; Kharchenko, P. V.; Scadden, D.
10.1101/2022.10.12.511184 — immunology — Posted on 2022-10-16
2269 Border-associated macrophages mediate the neuroinflammatory response in an alpha-synuclein model of Parkinson disease
Schonhoff, A. M.; Figge, D. A.; Jurkuvenaite, A. J.; Gallups, N. J.; Childers, G. M.; Webster, J. A.; Standaert, D. G.; Goldman, J. E.; Harms, A. S.
10.1101/2022.10.12.511960 — neuroscience — Posted on 2022-10-16
2270 Network Segregation in Aging Females and Evaluation of the Impact of Sex Steroid Hormones
Hicks, T. H.; Magalhaes, T. N. C.; Ballard, H. K.; Jackson, T. B.; Cox, S. J.; Bernard, J. A.
10.1101/2022.10.12.511918 — neuroscience — Posted on 2022-10-16
2277 Diversity-oriented synthesis encoded by deoxyoligonucleotides
Hudson, L.; Mason, J. W.; Westphal, M. V.; Richter, M. J. R.; Thielman, J. R.; Hua, B. K.; Gerry, C. J.; Xia, G.; Osswald, H. L.; Knapp, J. M.; Tan, Z. Y.; Kokkonda, P.; Tresco, B. I. C.; Liu, S.; Reidenbach, A. G.; Lim, K. S.; Poirier, J.; Capece, J.; Bonazzi, S.; Gampe, C. M.; Smith, N. J.; Bradner, J. E.; Coley, C. W.; Clemons, P. A.; Melillo, B.; Ottl, J.; Dumelin, C. E.; Schaefer, J. V.; Faust, A. M. E.; Berst, F.; Schreiber, S. L.; Zecri, F. J.; Briner, K.
10.1101/2022.10.16.512431 — biochemistry — Posted on 2022-10-16
2278 The Ycf48 accessory factor occupies the site of the oxygen-evolving manganese cluster during photosystem II biogenesis
Zhao, Z.; Vercellino, I.; Knoppova, J.; Sobotka, R.; Murray, J. W.; Nixon, P.; Sazanov, L.; Komenda, J.
10.1101/2022.10.16.512410 — biochemistry — Posted on 2022-10-16
2279 Diving Behavior Reveals Humidity Sensing Ability of Water Deprived Planarians
Pei, Y.; Qian, R.; Yan, Y.; Zhang, Y.; Tan, L.; Li, X.; Lu, C.; Chen, Y.; Chi, Y.; Hao, K.; Xu, Z.; Yang, G.; Shao, Z.; Wang, Y.; Huang, K.
10.1101/2022.10.12.511880 — animal behavior and cognition — Posted on 2022-10-16
2280 Lifespan Extension in Female Mice By Early, Transient Exposure to Adult Female Olfactory Cues
Garratt, M.; Erturk, I.; Alonzo, R.; Zufall, F.; Leinders-Zufall, T.; Pletcher, S. D.; Miller, R. A.
10.1101/2022.10.07.511218 — evolutionary biology — Posted on 2022-10-16
2282 Bacterial anomalies in seabed sediments associated with deep water hydrocarbon seepage
Li, C.; Adebayo, O.; Ferguson, D. K.; Wang, S.; Rattray, J. E.; Fowler, M.; Webb, J.; Campbell, C.; Morrison, N.; MacDonald, A.; Hubert, C. R.
10.1101/2022.10.15.512386 — microbiology — Posted on 2022-10-16
2284 Post-Influenza Environment Reduces Aspergillus fumigatus Conidia Clearance and Facilitates Invasive Aspergillosis In Vivo
Liu, K.-W.; Grau, M. S.; Jones, J. T.; Wang, X.; Vesely, E. M.; James, M. R.; Gutierrez-Perez, C.; Cramer, R. A.; Obar, J. J.
10.1101/2022.10.14.512336 — immunology — Posted on 2022-10-16
2285 Directed evolution of aerotolerance in sulfide-dependent thiazole synthases
Van Gelder, K.; Ramos de Oliveira Filho, E.; Garcia-Garcia, J. D.; Hu, Y.; Bruner, S. D.; Hanson, A. D.
10.1101/2022.10.16.512417 — synthetic biology — Posted on 2022-10-16
2286 Host Variation in Type I Interferon Signaling Genes (MX1), CCR5{triangleup}32, and MHC Class I Alleles in Treated HIV+ Non-Controllers Predict Viral Reservoir Size
Siegel, D. A.; Thanh, C.; Wan, E.; Hoh, R.; Hobbs, K.; Pan, T.; Gibson, E. A.; Kroetz, D. L.; Hunt, P. W.; Martin, J.; Hecht, F.; Pilcher, C.; Milush, J.; Martin, M.; Carrington, M.; Pillai, S.; Busch, M. P.; Stone, M.; Levy, C. N.; Huang, M.-L.; Roychoundhury, P.; Hladik, F.; Jerome, K. R.; Kiem, H.-P.; Heinrich, T. J.; Deeks, S. G.; Lee, S.
10.1101/2021.10.31.466670 — genomics — Posted on 2022-10-16
2289 Coding of latent variables in sensory, parietal, and frontal cortices during virtual closed-loop navigation
Noel, J.-P.; Balzani, E.; Avila, E.; Lakshminarasimhan, K.; Bruni, S.; Alefantis, P.; Savin, C.; Angelaki, D.
10.1101/2021.10.22.465526 — neuroscience — Posted on 2022-10-16
2291 White Adipose Tissue Compositional and Transcriptional Patterns with Progressive Glucose Intolerance in Persons with HIV
Bailin, S. S.; Kropski, J. A.; Gangula, R. D.; Hannah, L.; Simmons, J. D.; Mashayekhi, M.; Ye, F.; Fan, R.; Mallal, S.; Warren, C. M.; Kalams, S. A.; Gabriel, C. L.; Wanjalla, C. N.; Koethe, J. R.
10.1101/2022.03.21.484794 — immunology — Posted on 2022-10-16
2292 POU6F2 mutation identified in humans with pubertal failure shifts isoform formation and alters GnRH transcript expression
Cho, H.-J.; Gurbuz, F.; Stamou, M.; Kotan, L. D.; Farmer, S. M.; Can, S.; Tompkins, M. F.; Mammadova, J.; Altincik, S. A.; Gokce, C.; Catli, G.; Bugrul, F.; Bartlett, K.; Turan, I.; Balasubramanian, R.; Yuksel, B.; Seminara, S.; Wray, S.; Topaloglu, A. K.
10.1101/2022.10.12.511883 — genetics — Posted on 2022-10-16
2293 Quantifying climate change impacts on plant functional composition and soil nitrogen fixation in Mediterranean grasslands
Bomfim, B.; Dawson, H. R.; Reed, P. B.; Shek, K. L.; Bridgham, S. D.; Bohannan, B. J. M.; Silva, L. C. R.
10.1101/2022.09.16.508323 — ecology — Posted on 2022-10-16
2294 A penultimate classification of canonical antibody CDR conformations
Kelow, S.; Faezov, B.; Xu, Q.; Parker, M. I.; Adolf-Bryfogle, J.; Dunbrack, R. L.
10.1101/2022.10.12.511988 — immunology — Posted on 2022-10-16
2296 An expandable FLP-ON::TIR1 system for precise spatiotemporal protein degradation in C. elegans
Xiao, Y.; Yee, C.; Martinez, M. A. Q.; Zhao, C. Z.; Zhang, W.; Shen, K.; Matus, D. Q.; Hammell, C. M.
10.1101/2022.10.14.512315 — developmental biology — Posted on 2022-10-16
2297 Long-read genome sequencing accelerated the cloning of Pm69 by resolving the complexity of a rapidly evolving resistance gene cluster in wheat
Li, Y.; Wei, Z.-Z.; Sela, H.; Govta, L.; Klymiuk, V.; Roychowdhury, R.; Chawla, H. S.; Ens, J.; Wiebe, K.; Bocharova, V.; Ben-David, R.; Pawar, P. B.; Jaiwar, S.; Molnar, I.; Dolezel, J.; Pozniak, C. J.; Fahima, T.
10.1101/2022.10.14.512294 — genetics — Posted on 2022-10-16
2299 VECTRON™ T500, a new broflanilide insecticide for indoor residual spraying, provides prolonged control of pyrethroid-resistant malaria vectors
Govoetchan, R.; Fongnikin, A.; Syme, T.; Small, G.; Gbegbo, M.; Todjinou, D.; Rowland, M.; Nimmo, D.; Padonou, G. G.; Ngufor, C.
10.1101/2022.10.12.511866 — zoology — Posted on 2022-10-16
2304 A unified model for the dynamics of ATP-independent ultrafast contraction
Floyd, C.; Molines, A. T.; Lei, X.; Honts, J. E.; Chang, F.; Elting, M. W.; Vaikuntanathan, S.; Dinner, A. R.; Bhamla, M. S.
10.1101/2022.10.14.512304 — biophysics — Posted on 2022-10-16
2306 The Molecular and Evolutionary Principles of Histone Folding in Eukarya and Archaea
Zhao, H.; Wu, H.; Guseman, A.; Abeykoon, D.; Camara, C. M.; Dalal, Y.; Fushman, D.; Papoian, G.
10.1101/2022.10.15.512373 — biophysics — Posted on 2022-10-16
2308 Non-viral gene editing in utero with lipid nanoparticles complexed to mRNA
Gao, K.; Li, J.; Song, H.; Han, H.; Wang, Y.; Yin, B.; Farmer, D. L.; Murthy, N.; Wang, A.
10.1101/2022.10.14.512310 — genetics — Posted on 2022-10-16
2309 Engineered SMCHD1 and D4Z4 mutations reveal roles of D4Z4 heterochromatin disruption and feedforward DUX4 network activation in FSHD
Kong, X.; Nguyen, N. V.; Li, Y.; Sakr, J. S.; Williams, K.; Sharifi, S.; Chau, J.; Bayrakci, A.; Mizuno, S.; Takahashi, S.; Kiyono, T.; Tawil, R.; Mortazavi, A.; Yokomori, K.
10.1101/2022.10.14.512332 — genetics — Posted on 2022-10-16
2310 Historical dispersal and host-switching formed the evolutionary history of a globally distributed multi-host parasite - the Ligula intestinalis species complex
Nazarizadeh, M.; Novakova, M.; Loot, G.; Gabagambi, N. P.; Fatemizadeh, F.; Osano, O.; Presswell, B.; Poulin, R.; Vital, Z.; Scholz, T.; Halajian, A.; Trucchi, E.; Kocova, P.; Stefka, J.
10.1101/2022.10.12.511855 — evolutionary biology — Posted on 2022-10-16
2312 Epigenetic and transcriptional plasticity of myeloid cells in Cystic Fibrosis
Dinan, A. M.; Eneje, O.; Brown, K. P.; Burden, F.; Morse, M.; Prinjha, R.; Frontini, M.; Floto, R. A.
10.1101/2022.10.12.511886 — immunology — Posted on 2022-10-16
2317 Chromosome decompaction and cohesin direct Topoisomerase II activity to establish and maintain an unentangled interphase genome
Hildebrand, E. M.; Polovnikov, K.; Dekker, B.; Liu, Y.; Lafontaine, D. L.; Fox, A. N.; Li, Y.; Venev, S. V.; Mirny, L. A.; Dekker, J.
10.1101/2022.10.15.511838 — genomics — Posted on 2022-10-16
2321 β-catenin-dependent endomesoderm specification appears to be a Bilateria-specific co-option
Lebedeva, T.; Bostroem, J.; Moersdorf, D.; Niedermoser, I.; Genikhovich, E.; Adameyko, I.; Genikhovich, G.
10.1101/2022.10.15.512282 — developmental biology — Posted on 2022-10-16
2322 Manipulating Oxalate Decarboxylase Provides the Basis of Antilithic Therapy by Acting on the Gut Microbiota
Wu, F.; Cheng, Y.; Zhou, J.; Ye, P.; Liu, X.; Zhang, L.; Lin, R.; Xiang, S.; Liu, Z.; Wang, C.
10.1101/2022.10.14.512337 — cell biology — Posted on 2022-10-16
2324 Aromatic amino acid biosynthesis by a Lotus Aldolase impacts root hair development and symbiotic associations
Montiel, J.; James, E. K.; Garcia-Soto, I.; Reid, D. E.; Napsucialy-Mendivil, S.; Dubrovsky, J. G.; Cardenas, L.; Stougaard, J.
10.1101/2022.10.13.511206 — plant biology — Posted on 2022-10-16
2325 Root-knot nematodes produce functional mimics of tyrosine-sulfated plant peptides
Yimer, H. Z.; Luu, D. D.; Blundell, A. C.; Ercoli, M. F.; Vieira, P.; Williamson, V. M.; Ronald, P. C.; Siddique, S.
10.1101/2022.10.13.511487 — plant biology — Posted on 2022-10-16
2327 Astrocyte 3D Culture and Bioprinting using Peptide Functionalized Hyaluronan Hydrogels
Matthiesen, I.; Jury, M.; Rasti Boroojeni, F.; Ludwig, S. L.; Holzreuter, M.; Buchmann, S.; Träger, A. A.; Selegard, R.; Winkler, T. E.; Aili, D. E.; Herland, A.
10.1101/2022.10.13.510969 — bioengineering — Posted on 2022-10-15
2328 Elucidation of Global Trends in the Effects of VX-661 and VX-445 on the Expression of Clinical CFTR Variants
McKee, A. G.; McDonald, E. F.; Penn, W. D.; Kuntz, C. P.; Noguera, K.; Chamness, L. M.; Roushar, F. J.; Meiler, J.; Oliver, K. E.; Plate, L.; Schlebach, J. P.
10.1101/2022.10.14.512300 — biochemistry — Posted on 2022-10-15
2337 The rat frontal cortex encodes a value map for economic decisions under risk
Zhu, X.; Bao, C.; Moller-Mara, J.; Li, J.; Dubroqua, S.; Erlich, J. C.
10.1101/2021.11.19.469107 — neuroscience — Posted on 2022-10-15
2338 The SARS-CoV-2 spike N-terminal domain engages 9-O-acetylated α2-8-linked sialic acids
Tomris, I.; Unione, L.; Nguyen, L.; Zaree, P.; Bouwman, K. M.; Liu, L.; Li, Z.; Fok, J. A.; Rios Carrasco, M.; van der Woude, R.; Kimpel, A. L. M.; Linthorst, M. W.; Verpalen, E. C. J. M.; Caniels, T. G.; Sanders, R. W.; Heesters, B. A.; Pieters, R. J.; Jimenez-Barbero, J.; Klassen, J. S.; Boons, G.-J.; de Vries, R. P.
10.1101/2022.09.14.507904 — molecular biology — Posted on 2022-10-15
2340 Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single cell resolution
Resztak, J. A.; Wei, J.; Zilioli, S.; Sendler, E.; Alazizi, A.; Mair-Meijers, H. E.; Wu, P.; Wen, X.; Slatcher, R. B.; Zhou, X.; Luca, F.; Pique-Regi, R.
10.1101/2021.09.30.462672 — genomics — Posted on 2022-10-15
2341 Mesoscopic in vivo human T2* dataset acquired using quantitative MRI at 7 Tesla
Gulban, O. F.; Bollmann, S.; Huber, R.; Wagstyl, K.; Goebel, R.; Poser, B. A.; Kay, K.; Ivanov, D.
10.1101/2021.11.25.470023 — neuroscience — Posted on 2022-10-15
2342 Natural gradient enables fast sampling in spiking neural networks
Masset, P.; Zavatone-Veth, J. A.; Connor, J. P.; Murthy, V. N.; Pehlevan, C.
10.1101/2022.06.03.494680 — neuroscience — Posted on 2022-10-15
2343 Removal of pomt1 in zebrafish leads to loss of α-dystroglycan glycosylation and dystroglycanopathy phenotypes
Karas, B. F.; Terez, K. R.; Battula, N.; Gural, B. M.; Flannery, K. P.; Aboussleman, G.; Mubin, N.; Manzini, C.
10.1101/2022.10.15.512359 — neuroscience — Posted on 2022-10-15
2349 Taxonomy of introns, their evolution, and the role of minor introns in stress response
Olthof, A. M.; Schwoerer, C. F.; Weber, A. L.; Arokiadhas, I.; Doggett, K.; Mieruszynski, S.; Cnaani, A.; Heath, J. K.; Biran, J.; Kanadia, R. N.
10.1101/2022.10.12.511939 — molecular biology — Posted on 2022-10-14
2356 Cleavage of α-1,4-Glycosidic Linkages by the Glycosylphosphatidylinositol-Anchored α-Amylase AgtA Decreases the Molecular Weight of Cell Wall α-1,3-Glucan in Aspergillus oryzae
Koizumi, A.; Miyazawa, K.; Ogata, M.; Takahashi, Y.; Yano, S.; Yoshimi, A.; Sano, M.; Hidaka, M.; Nihira, T.; Nakai, H.; Kimura, S.; Iwata, T.; Abe, K.
10.1101/2022.10.12.511150 — microbiology — Posted on 2022-10-14
2357 Human gut Actinobacteria boost drug absorption by secreting P-glycoprotein ATPase inhibitors
Kyaw, T. S.; Sandy, M.; Trepka, K.; Goh, J.; Yu, K.; Dimassa, V.; Bess, E.; Bisanz, J.; Turnbaugh, P. J.
10.1101/2022.10.13.512142 — microbiology — Posted on 2022-10-14
2358 Host association and intracellularity evolved multiple times independently in the Rickettsiales
Castelli, M.; Nardi, T.; Gammuto, L.; Bellinzona, G.; Sabaneyeva, E.; Potekhin, A.; Serra, V.; Petroni, G.; Sassera, D.
10.1101/2022.10.13.511287 — microbiology — Posted on 2022-10-14
2359 Inhibition of Microbial Methane Oxidation by 2-Chloro-6-Methylpyridine
O'Loughlin, E. J.; Antonopoulos, D. A.; Arend, K. K.; Flynn, T. M.; Koval, J. C.; Owens, S. M.
10.1101/2022.10.13.512149 — microbiology — Posted on 2022-10-14
2361 Deciphering the non-coding code of pathogenicity and sexual differentiation in the human malaria parasite.
Batugedara, G.; Lu, X. M.; Abel, S.; Chahine, Z.; Hristov, B.; Williams, D.; Hollin, T.; Wang, T.; Cort, A.; Lenz, T.; Thompson, T.; Prudhomme, J.; Tripathi, A. K.; Xu, G.; Cudini, J.; Dogga, S.; Lawniczak, M.; Stafford Noble, W.; Sinnis, P.; Le Roch, K. G.
10.1101/2022.10.12.511630 — microbiology — Posted on 2022-10-14
2363 The substitutions L50F, E166A and L167F in SARS-CoV-2 3CLpro are selected by a protease inhibitor in vitro and confer resistance to nirmatrelvir
Jochmans, D.; Liu, C.; Donckers, K.; Stoycheva, A.; Boland, S.; Stevens, S. K.; De Vita, C.; Vanmechelen, B.; Maes, P.; Trüeb, B. S.; Ebert, N.; Thiel, V.; De Jonghe, S.; Vangeel, L.; Bardiot, D.; Jekle, A.; Blatt, L. M.; Beigelman, L.; Symons, J. A.; Raboisson, P.; Chaltin, P.; Marchand, A.; Neyts, J.; Deval, J.; Vandyck, K.
10.1101/2022.06.07.495116 — microbiology — Posted on 2022-10-14
2367 Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1Omicron
Chen, D.-Y.; Kenney, D.; Chin, C.-V.; Tavares, A. H.; Khan, N.; Conway, H. L.; Liu, G.; Choudhary, M. C.; Gertje, H. P.; OConnell, A. K.; Kotton, D. N.; Herrmann, A.; Ensser, A.; Connor, J. H.; Bosmann, M.; Li, J. Z.; Gack, M. U.; Baker, S. C.; Kirchdoerfer, R. N.; Kataria, Y.; Crossland, N. A.; Douam, F.; Saeed, M.
10.1101/2022.10.13.512134 — microbiology — Posted on 2022-10-14
2369 Rapid transmission and tight bottlenecks constrain the evolution of highly transmissible SARS-CoV-2 variants
Bendall, E. E.; Callear, A.; Getz, A.; Goforth, K.; Edwards, D.; Monto, A.; Martin, E. T.; Lauring, A. S.
10.1101/2022.10.12.511991 — microbiology — Posted on 2022-10-14
2371 TsTX-kappa beta (Ts8), a neurotoxin from the venom of the scorpion Tityus serrulatus: antimicrobial and hemolytic activity.
Oliveira, T. d. J.; Pereira, N.; Riciluca, K. C. T.; do Nascimento, S. M.; Castro de Oliveira, U.; Silva Junior, P. I.
10.1101/2022.10.09.511467 — microbiology — Posted on 2022-10-14
2372 Contribution of 6mer seed toxicity to HIV-1 induced cytopathicity
Vaidyanathan, A.; Taylor, H. E.; Hope, T. J.; D'Aquila, R. T.; Bartom, E. T.; Hultquist, J. F.; Peter, M. E.
10.1101/2022.10.01.510471 — microbiology — Posted on 2022-10-14
2374 Neuraminidase inhibitors rewire neutrophil function in vivo in murine sepsis and ex vivo in COVID-19
Formiga, R. O.; Amaral, F. C.; Souza, C. F.; Mendes, D. A. G. B.; Wanderley, C. W. S.; Lorenzini, C. B.; Santos, A. A.; Antonia, J.; Faria, L. F.; Natale, C. C.; Paula, N. M.; Silva, P. C. S.; Fonseca, F. R.; Aires, L.; Heck, N.; Starick, M. R.; Barroso, S. P. C.; Morrot, A.; Van Weyenbergh, J.; Sordi, R.; Alisson-Silva, F.; Mansur, D. S.; Cunha, F. Q.; Lummertz da Rocha, E.; Burgel, P.-R.; Martin, C.; Hurtado-Nedelec, M. M.; Martin, S. C.; Santos, F. R. S.; de Souza, F. R. O.; Queiroz-Junior, C. M.; Costa, V. V.; Maurici, R.; Macauley, M. S.; Bafica, A.; Witko-Sarsat, V.; Spiller, F.
10.1101/2020.11.12.379115 — immunology — Posted on 2022-10-14
2375 SARS-CoV-2 immune complex triggers human monocyte necroptosis
Santos, L.; Antunes, K. H.; Cassao, G.; Goncalves, J. I.; Abbadi, B. L.; Bizarro, C. V.; Basso, L. A.; Machado, P.; Souza, A. P. D. d.; Porto, B.
10.1101/2022.10.13.512127 — immunology — Posted on 2022-10-14
2376 Broad SARS-CoV-2 Neutralization by Monoclonal and Bispecific Antibodies Derived from a Gamma-infected Individual
Guerra, D.; Beaumont, T.; Radic, L.; Kerster, G.; van der Straten, K.; Yuan, M.; Torres, J. L.; Lee, W.-H.; Liu, H.; Poniman, M.; Bontjer, I.; Burger, J. A.; Claireaux, M.; Caniels, T. G.; Snitselaar, J. L.; Bijl, T. P. L.; Kruijer, S.; Ozorowski, G.; Gideonse, D.; Sliepen, K.; Ward, A. B.; Eggink, D.; de Bree, G. J.; Wilson, I. A.; Sanders, R. W.; van Gils, M. J.
10.1101/2022.10.14.512216 — immunology — Posted on 2022-10-14
2377 Pf Bacteriophage Inhibits Neutrophil Migration in the Lung
Popescu, M. C.; Pennetzdorfer, N.; Hargil, A.; Kaber, G.; Bollyky, P. L.
10.1101/2022.10.12.511980 — immunology — Posted on 2022-10-14
2378 Patterns of convergent somatic hypermutations in the adaptive immune response of Mus musculus
Wenner, A. C.; Mettler, C. M.; Sharp, E. M.; Hansen, T. C.; Vari, I. B.; Le, A. V.; Zimmermann, J.
10.1101/2022.10.12.510618 — immunology — Posted on 2022-10-14
2379 Candida albicans promotes neutrophil extracellular trap formation and leukotoxic hypercitrullination via the peptide toxin candidalysin.
Unger, L.; Backman, E.; Yellagunda, S.; Ponce-Garcia, F. M.; Amulic, B.; Renate, K.; von Bernuth, H.; Bylund, J.; Hube, B.; Naglik, J. R.; Urban, C. F.
10.1101/2022.10.13.512027 — immunology — Posted on 2022-10-14
2380 Myelin-reactive B cells exacerbate the severity of CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner.
Fazazi, M. R.; Doss, P. M. I. A.; Pereira, R.; Fudge, N.; Regmi, A.; Akbar, I.; Yeola, A. P.; Mailhot, B.; Baillargeon, J.; Grenier, P.; Bertrand, N.; Lacroix, S.; Moore, C. S.; Rojas, O. L.; Rangachari, M.
10.1101/721696 — immunology — Posted on 2022-10-14
2382 Transcriptomic diversity of cell types across the adult human brain
Siletti, K.; Hodge, R. D.; Mossi Albiach, A.; Hu, L.; Lee, K. W.; Lönnerberg, P.; Bakken, T. E.; Ding, S.-L.; Clark, M.; Casper, T.; Dee, N.; Gloe, J.; Keene, C. D.; Nyhus, J.; Tung, H.; Yanny, A. M.; Arenas, E.; Lein, E. S.; Linnarsson, S.
10.1101/2022.10.12.511898 — neuroscience — Posted on 2022-10-14
2384 Emergence of the cortical encoding of phonetic features in the first year of life
Di Liberto, G. M.; Attaheri, A.; Cantisani, G.; Reilly, R.; Ni Choisdealbha, A.; Rocha, S.; Brusini, P.; Goswami, U.
10.1101/2022.10.11.511716 — neuroscience — Posted on 2022-10-14
2387 Macro-scale patterns in functional connectivity associated with ongoing thought patterns and dispositional traits
Hardikar, S.; Mckeown, B.; Schaare, H. L.; Xu, T.; Lauckner, M.; Valk, S.; Margulies, D.; Turnbull, A.; Bernhardt, B.; Vos de Wael, R.; Villringer, A.; smallwood, j.
10.1101/2022.10.11.511591 — neuroscience — Posted on 2022-10-14
2388 Long-range inhibitory neurons mediate cortical neurovascular coupling
Ruff, C. F.; Juarez Anaya, F.; Dienel, S. J.; Rakymzhan, A.; Altamirano-Espinoza, A.; Couey, J.; Watson, A. M.; Fish, K. N.; Hooks, B. M.; Rubio, M. E.; Su, A.; Ross, S. E.; Vazquez, A. L.
10.1101/2022.10.11.511811 — neuroscience — Posted on 2022-10-14
2391 Thalamocortical networks involved in Pusher Syndrome
Rosenzopf, H.; Klingbeil, J.; Wawrzyniak, M.; Röhrig, L.; Sperber, C.; Saur, D.; Karnath, H.-O.
10.1101/2022.10.12.511887 — neuroscience — Posted on 2022-10-14
2393 Personalized Functional Brain Network Topography Predicts Individual Differences in Youth Cognition
Keller, A. S.; Pines, A. R.; Sydnor, V. J.; Cui, Z.; Bertolero, M. A.; Barzilay, R.; Alexander-Bloch, A.; Byington, N.; Chen, A. A.; Conan, G. M.; Davatazikos, C.; Feczko, E. J.; Hendrickson, T. J.; Houghton, A.; Larsen, B.; Li, H.; Miranda Dominguez, O.; Roalf, D. R.; Perrone, A.; Shanmugan, S.; Shinohara, R. T.; Fan, Y.; Fair, D. A.; Satterthwaite, T. D.
10.1101/2022.10.11.511823 — neuroscience — Posted on 2022-10-14
2395 Glutamatergic dysfunction leads to a hyper-dopaminergic phenotype through deficits in short-term habituation: a mechanism for aberrant salience.
Panayi, M. C.; Boerner, T.; Jahans-Price, T.; Huber, A.; Sprengel, R.; Gilmour, G.; Sanderson, D. J.; Harrison, P. J.; Walton, M. E.; Bannerman, D. M.
10.1101/2021.07.23.453593 — neuroscience — Posted on 2022-10-14
2397 Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and fibromyalgia are indistinguishable by their cerebrospinal fluid proteomes
Schutzer, S. E.; Liu, T.; Tsai, C.-F.; Petyuk, V. A.; Schepmoes, A.; Wang, Y.-T.; Weitz, K.; Bergquist, J.; Smith, R.; Natelson, B.
10.1101/2022.09.14.506792 — neuroscience — Posted on 2022-10-14
2398 Batch Effects are Causal Effects: Applications in Human Connectomics
Bridgeford, E. W.; Powell, M.; Kiar, G.; Noble, S.; Chung, J.; Panda, S.; Lawrence, R.; Milham, M.; Caffo, B.; Vogelstein, J. T.
10.1101/2021.09.03.458920 — neuroscience — Posted on 2022-10-14
2400 Microstimulation of human somatosensory cortex evokes task-dependent, spatially patterned responses in motor cortex
Shelchkova, N. D.; Downey, J. E.; Greenspon, C. M.; Okorokova, E. V.; Sobinov, A. R.; Verbaarschot, C.; He, Q.; Sponheim, C.; Tortolani, A. F.; Moore, D. D.; Kaufman, M. T.; Lee, R. C.; Satzer, D.; Gonzalez-Martinez, J.; Warnke, P. C.; Miller, L. E.; Boninger, M. L.; Gaunt, R.; Collinger, J.; Hatsopoulos, N.; Bensmaia, S. J.
10.1101/2022.08.10.503543 — neuroscience — Posted on 2022-10-14
2401 Immediate and Long-Term Effects of Tibial Nerve Stimulation on the Sexual Behavior of Female Rats
Zimmerman, L. L.; Mentzelopoulos, G.; Parrish, H.; Marcu, V. I.; Luma, B. D.; Becker, J. B.; Bruns, T.
10.1101/2022.06.20.496650 — neuroscience — Posted on 2022-10-14
2405 Is shape in the eye of the beholder? The reproducibility of geometric morphometric analyses on live animals
Moccetti, P.; Rodger, J. R.; Bolland, J. D.; Kaiser-Wilks, P.; Smith, R.; Nunn, A. D.; Adams, C. E.; Bright, J. A.; Honkanen, H. M.; Lothian, A. J.; Newton, M.; Joyce, D. A.
10.1101/2022.10.11.509915 — zoology — Posted on 2022-10-14
2407 Dynamic map illuminates Hippo to cMyc module crosstalk driving cardiomyocyte proliferation
Harris, B. N.; Woo, L. A.; Perry, R. N.; Civelek, M. J.; Wolf, M. J.; Saucerman, J. J.
10.1101/2022.10.11.511763 — systems biology — Posted on 2022-10-14
2408 Predictive nonlinear modeling of malignant myelopoiesis and tyrosine kinase inhibitor therapy
Rodriguez, J. D.; Iniguez, A.; Jena, N.; Tata, P.; Liu, J.; Lander, A. D.; Lowengrub, J.; Van Etten, R.
10.1101/2022.10.11.511822 — systems biology — Posted on 2022-10-14
2413 Are female scientists underrepresented in self-correcting science for honest error?
Ribeiro, M. D.; Mena-Chalco, J.; Rocha, K. d. A.; Pedrotti, M.; Menezes, P.; Vasconcelos, S. M.
10.1101/2022.10.11.511375 — scientific communication and education — Posted on 2022-10-14
2414 Improved Protocol for Single Nucleus RNA-sequencing of Frozen Human Bladder Tumor Biopsies
Schmoekel, S. S.; Nordentoft, I. K.; Lindskrog, S. V.; Lamy, P.; Knudsen, M.; Jensen, J. B.; Dyrskjoet, L.
10.1101/2022.10.14.512220 — cancer biology — Posted on 2022-10-14
2415 Treatment of prostate cancer with CD46 targeted 225Ac alpha particle radioimmunotherapy
Bidkar, A. P.; Wang, S.; Bobba, K. N.; Chan, E.; Bidlingmaier, S.; Egusa, E. A.; Peter, R.; Ali, U.; Meher, N.; Wadhwa, A.; Dhrona, S.; Beckford-Vera, D.; Su, Y.; Tang, R.; Zhang, L.; He, J.; Wilson, D. M.; Aggarwal, R.; VanBrocklin, H. F.; Seo, Y.; Chou, J.; Liu, B.; Flavell, R. R.
10.1101/2022.10.13.512165 — cancer biology — Posted on 2022-10-14
2416 Iron Inhibits Glioblastoma Cell Migration and Polarization
Shenoy, G.; Kheirabadi, S.; Ataie, Z.; Palsa, K.; Wade, Q.; Khunsriraksakul, C.; Khristov, V.; Slagle-Webb, B.; Lathia, J.; Wang, H.-G.; Sheikhi, A.; Connor, J. R.
10.1101/2022.10.13.512175 — cancer biology — Posted on 2022-10-14
2417 PHYTOCHROME C regulation of PHOTOPERIOD1 is mediated by EARLY FLOWERING 3 in Brachypodium distachyon
Woods, D. P.; Li, W.; Sibout, R.; Shao, M.; Laudencia-Chingcuanco, D.; Vogel, J.; Dubcovsky, J.; Amasino, R.
10.1101/2022.10.11.511813 — plant biology — Posted on 2022-10-14
2418 The translational role of SOS1 in colorectal cancer
Alem, D.; Yang, X.; Beato, F.; Sarcar, B.; Tassielli, A. F.; Dai, R.; Hogenson, T. L.; Park, M. A.; Jiang, K.; Cai, J.; Yuan, Y.; Fernandez-Zapico, M. E.; Tan, A. C.; Fleming, J. B.; Xie, H.
10.1101/2022.10.14.512156 — cancer biology — Posted on 2022-10-14
2420 Analysis of Skin Cancers from Xeroderma Pigmentosum Patients Reveals Heterogeneous UV-Induced Mutational Profiles Shaped by DNA Repair
Yurchenko, A. A.; Rajabi, F.; Braz-Petta, T.; Fassihi, H.; Lehmann, A.; Nishigori, C.; Padioleau, I.; Gunbin, K.; Panunzi, L.; Morice-Picard, F.; Laplante, P.; Robert, C.; Kannouche, P.; Menck, C. F. M.; Sarasin, A.; Nikolaev, S. I.
10.1101/2022.10.14.512263 — cancer biology — Posted on 2022-10-14
2422 Population Transcriptome and Phenotype Reveal that the Rht-D1b Contribute a Larger Seedling Roots to Modern Wheat Cultivars
Wang, X.; Zhao, P.; Guo, X.; Liu, Z.; Ma, X.; Zhao, Y.; Lai, X.; Huang, L.; Wang, W.; Han, D.; Kang, Z.; Xu, S.
10.1101/2022.06.02.494553 — plant biology — Posted on 2022-10-14
2423 ACSM1 and ACSM3 regulate prostate cancer fatty acid metabolism to promote tumour growth and constrain ferroptosis
Shrestha, R.; Nassar, Z. D.; Hanson, A. R.; Iggo, R.; Townley, S. L.; Dehairs, J.; Mah, C. Y.; Helm, M.; Alizadeh-Ghodsi, M.; Pickering, M.; Watt, M. J.; Quek, L.-E.; Hoy, A. J.; Tilley, W. D.; Swinnen, J. V.; Butler, L. M.; Selth, L. A.
10.1101/2022.10.13.511039 — cancer biology — Posted on 2022-10-14
2424 The potentiative cytotoxic effect of IGF1R and EGFR inhibition on the Head and Neck Cancer Proteome
Hall, S.; Lehman, C.; Wulfkuhle, J.; Petricoin, E.; Bekiranov, S.; Dolatshahi, S.; Jameson, M.; Gioeli, D.
10.1101/2022.10.13.512093 — cancer biology — Posted on 2022-10-14
2425 FOXA2 controls the anti-oxidant response in FH-deficient cells
Rogerson, C.; Sciacovelli, M.; Maddalena, L. A.; Valcarcel-Jimenez, L.; Schmidt, C.; Yang, M.; Ivanova, E.; Kent, J.; Mora, A.; Cheeseman, D.; Carroll, J. S.; Kelsey, G.; Frezza, C.
10.1101/2022.07.04.498412 — cancer biology — Posted on 2022-10-14
2426 Therapeutic modulation of the blood-brain barrier and ischemic stroke by a bioengineered FZD4-selective WNT surrogate
Ding, J.; Lee, S.-J.; Vlahos, L.; Yuki, K.; Rada, C.; van Unen, V.; Vuppalapaty, M.; Chen, H.; Sura, A.; McCormick, A.; Tomaske, M.; Alwahabi, S.; Nguyen, H.; Nowatzke, W.; Kim, L.; Kelly, L.; Vollrath, D.; Califano, A.; Yeh, W.-C.; Li, Y.; Kuo, C.
10.1101/2022.10.13.510564 — physiology — Posted on 2022-10-14
2427 Distinct functions of cardiac β-adrenergic receptors in the T-tubule vs. outer surface membrane
BARTHE, M.; LEFEBVRE, F.; LANGLOIS, E.; LEFEBVRE, F.; LECHENE, P.; ITURRIOZ, X.; LLORENS-CORTES, C.; HA-DUONG, T.; MOINE, L.; TSAPIS, N.; FISCHMEISTER, R.
10.1101/2021.04.28.441732 — physiology — Posted on 2022-10-14
2430 A Generalizable Nanopore Sensor for Highly Specific Protein Detection at Single-Molecule Precision
Ahmad, M.; Ha, J.-H.; Mayse, L.; Presti, M.; Wolfe, A. J.; Moody, K. J.; Loh, S. N.; Movileanu, L.
10.1101/2022.10.12.511930 — biophysics — Posted on 2022-10-14
2431 Mechanobiology of Fibroblast Activation in Skin Grafting
Hong, Y.; Peng, X.; Yu, H.; Jafari, M.; Shakiba, D.; Sandler, J.; Pryse, K.; Elson, E.; Genin, G.; Alisafaei, F.
10.1101/2022.10.12.511903 — biophysics — Posted on 2022-10-14
2434 Estimation of crossbridge-state during cardiomyocyte beating using second harmonic generation
Watanabe, T. M.; Fujita, H.; Kaneshiro, J.; Takeda, M.; Sasaki, K.; Yamamoto, R.; Umetsu, D.; Kuranaga, E.; Higo, S.; Kondo, T.; Asano, Y.; Sakata, Y.; Miyagawa, S.
10.1101/2022.10.13.512034 — biophysics — Posted on 2022-10-14
2435 Triggered functional dynamics of AsLOV2 by time-resolved electron paramagnetic resonance at high magnetic fields
Maity, S.; Price, B. D.; Wilson, C. B.; Mukherjee, A.; Starck, M.; Parker, D.; Wilson, M. Z.; Lovett, J. E.; Han, S.; Sherwin, M. S.
10.1101/2022.10.12.511365 — biophysics — Posted on 2022-10-14
2438 Emergent oscillations during cellular directional decision-making on junctions
Ron, J. E.; Crestani, M.; Kux, J.-M.; Liu, J.; Al-Dam, N.; Monzo, P.; Gauthier, N. C.; Saez, P. J.; Gov, N. S.
10.1101/2022.10.14.512239 — biophysics — Posted on 2022-10-14
2446 Enhancer/gene relationships: need for more reliable genome-wide reference sets
Hoellinger, T.; Mestre, C.; Aschard, H.; Le Goff, W.; Foissac, S.; Faraut, T.; Djebali, S.
10.1101/2022.10.12.511908 — bioinformatics — Posted on 2022-10-14
2447 Multiple-trait subsampling for optimized ancestral trait reconstruction
Li, X.; Trovao, N. S.; Wertheim, J. O.; Baele, G.; de Bernardi Schneider, A.
10.1101/2022.10.11.511762 — bioinformatics — Posted on 2022-10-14
2449 Risk Stratification of Acute Myeloid Leukemia Using Ex Vivo Drug Sensitivity Profiling
Brodersen, A.; Andersen, A.; Ayuda-Duran, P.; Tadele, D.; Piechaczyk, L.; Baken, L.; Fredriksen, J.; Stoksflod, M.; Lenartova, A.; Floisand, Y.; Enserink, J.
10.1101/2022.10.11.509866 — bioinformatics — Posted on 2022-10-14
2451 Deep autoencoder for interpretable tissue-adaptive deconvolution and cell-type-specific gene analysis
Chen, Y.; Wang, Y.; Chen, Y.; Cheng, Y.; Wei, Y.; Li, Y.; Wang, J.; Wei, Y.; Chan, T.-F.; Li, Y.
10.1101/2021.10.26.465846 — bioinformatics — Posted on 2022-10-14
2459 An integrated cell barcoding and computational analysis pipeline for scalable analysis of differentiation at single-cell resolution
Shen, S.; Werner, T.; Sun, Y.; Shim, W. J.; Lukowski, S.; Andersen, S.; Chiu, H. S.; Xia, D.; Chen, X.; Pham, D.; Su, Z.; Powell, J. E.; Tam, P. P. L.; Boden, M.; Ho, J. W. K.; Nguyen, Q.; Palpant, N. J.
10.1101/2022.10.12.511862 — genomics — Posted on 2022-10-14
2461 CRISPRa screening with real world evidence identifies potassium channels as neuronal entry factors and druggable targets for SARS-CoV-2
Wang, C.; Dinesh, R.; Qu, Y.; Rustagi, A.; Cousins, H.; Zengel, J.; Zhang, T.; Magazine, N.; Guo, Y.; Hall, T.; Beck, A.; Heilbroner, L.; Peters-Schulze, G.; Wilk, A.; Tso, L.; Erdemic, E.; Tanudtanud, K.; Ren, S.; Tzeng, K. T.-H.; Wang, M.; Howitt, B.; Huang, W.; Carette, J.; Altman, R.; Blish, C.; Cong, L.
10.1101/2021.07.01.450475 — genomics — Posted on 2022-10-14
2462 Transparent and stretchable metal nanowire composite recording microelectrode arrays
Chen, Z.; Nguyen, K.; Kowalik, G.; Shi, X.; Tian, J.; Doshi, M.; Alber, B. R.; Ning, X.; Kay, M. W.; Lu, L.
10.1101/2022.10.11.511842 — bioengineering — Posted on 2022-10-14
2463 Palidis: fast discovery of novel insertion sequences
Carr, V. R.; Pissis, S. P.; Mullany, P.; Shoaie, S.; Gomez-Cabrero, D.; Moyes, D. L.
10.1101/2022.06.27.497710 — genomics — Posted on 2022-10-14
2464 Multiscale functional connectivity patterns of the aging brain learned from rsfMRI data of 4,259 individuals of the multi-cohort iSTAGING study
Zhou, Z.; Srinivasan, D.; Li, H.; Abdulkadir, A.; Nasrallah, I.; Wen, J.; Doshi, J.; Erus, G.; Mamourian, E.; Bryan, N. R.; Wolk, D. A.; Beason-Held, L.; Resnick, S. M.; Satterthwaite, T. D.; Davatzikos, C.; Shou, H.; Fan, Y.
10.1101/2022.07.27.501626 — bioengineering — Posted on 2022-10-14
2465 142 telomere-to-telomere assemblies reveal the genome structural landscape in Saccharomyces cerevisiae
O'Donnell, S.; Yue, J.-X.; Abou Saada, O.; Agier, N.; Caradec, C.; Cokelaer, T.; De Chiara, M.; Delmas, S.; Dutreux, F.; Fournier, T.; Friedrich, A.; Kornobis, E.; Li, J.; Miao, Z.; Tattini, L.; Schacherer, J.; Liti, G.; Fischer, G.
10.1101/2022.10.04.510633 — genomics — Posted on 2022-10-14
2466 Precisely patterned nanofibers made from extendable protein multiplexes
Bethel, N. P.; Borst, A. J.; Parmeggiani, F.; Bick, M. J.; Brunette, T.; Nguyen, H.; Kang, A.; Bera, A. K.; Carter, L.; Miranda, M. C.; Kibler, R.; Lamb, M.; Li, X.; Sankaran, B.; Baker, D.
10.1101/2022.10.14.511843 — bioengineering — Posted on 2022-10-14
2467 Kinase Inhibitor Pulldown Assay (KiP) for Clinical Proteomics
Saltzman, A. B.; Chan, D.; Holt, M. V.; Wang, J.; Jaehnig, E. J.; Anurag, M.; Singh, P.; Malovannaya, A.; Kim, B.-J.; Ellis, M. J.
10.1101/2022.10.13.511593 — biochemistry — Posted on 2022-10-14
2468 Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries
Zheng, Z.; Liu, S.; Sidorenko, J.; Yengo, L.; Turley, P.; Ani, A.; Wang, R.; Nolte, I. M.; Snieder, H.; Lifelines Cohort Study, ; Yang, J.; Wray, N. R.; Goddard, M. E.; Visscher, P. M.; Zeng, J.
10.1101/2022.10.12.510418 — genetics — Posted on 2022-10-14
2469 Structures of FtsZ from a cell-wall less bacterium Spiroplasma provide a mechanism for kinetic polarity
Chakraborty, J.; Poddar, S. M.; Dutta, S.; Bahulekar, V.; Harne, S.; SRINIVASAN, R.; Gayathri, P.
10.1101/2022.10.13.512043 — biochemistry — Posted on 2022-10-14
2470 A meta-analysis of genome-wide association studies identifies new genetic loci associated with all-cause and vascular dementia
Fongang, B.; Sargurupremraj, M.; Jian, X.; Mishra, A.; Damotte, V.; Bis, J. C.; Kang-Hsien, F.; Li, G.; Yang, J.; Hilal, S.; Knol, M. J.; Concas, M. P.; Giorgia, G.; Riaz, M.; Guojunsson, A.; Lacaze, P.; Naj, A. C.; van der Lee, S. J.; Goss, M.; Ngouongo, Y. W.; Skrobot, O.; Guonason, V.; Launer, L.; Oscar, L.; Mary, H.; Bosnes, I.; Dufouil, C.; Ganguli, M.; Cheung, C.-L.; Bennett, D. A.; Chen, C.; Ilyas, K. M.; Satizabal, C.; Ikram, A. M.; Debette, S.; Fornage, M.; Qiong, Y.; Schellenberg, G. D.; Winsvold, B.; Kehoe, P. G.; Ruiz, A.; Lambert, J.-C.; Weinstein, G.; Seshadri, S.
10.1101/2022.10.11.509802 — genetics — Posted on 2022-10-14
2475 DNMT1 inhibition by pUG-fold quadruplex RNA
Jansson-Fritzberg, L. I.; Sousa, C. I.; Smallegan, M. J.; Song, J. J.; Gooding, A. R.; Kasinath, V.; Rinn, J. L.; Cech, T. R.
10.1101/2022.10.14.512272 — biochemistry — Posted on 2022-10-14
2476 Predicting recombination frequency from map distance
Kivikoski, M.; Rastas, P.; Löytynoja, A.; Merilä, J.
10.1101/2020.12.14.422614 — genetics — Posted on 2022-10-14
2477 CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands
Rouillon, C.; Eckhardt, B. V.; Kollenstart, L.; Gruss, F.; Verkennis, A. E. E.; Rondeel, I.; Krijger, P. H. L.; Ricci, G.; Biran, A.; van Laar, T.; Delvaux de Fenffe, C. M.; Luppens, G.; Albanese, P.; Scheltema, R. A.; de Laat, W.; Dekker, N. H.; Groth, A.; Mattiroli, F.
10.1101/2022.10.14.512229 — biochemistry — Posted on 2022-10-14
2480 The first archaeal PET-degrading enzyme belongs to the feruloyl-esterase family
Perez-Garcia, P.; Chow, J.; Costanzi, E.; Gurschke, M. F.; Dittrich, J.; Dierkes, R. F.; Applegate, V.; Feuerriegel, G.; Tete, P.; Danso, D.; Schumacher, J.; Pfleger, C.; Gohlke, H.; Smits, S. H. J.; Schmitz, R. A.; Streit, W. R.
10.1101/2022.10.14.512230 — biochemistry — Posted on 2022-10-14
2481 Body size as a magic trait in two plant-feeding insect species
Glover, A. N.; Bendall, E. E.; Terbot, J. W.; Payne, N.; Webb, A.; Filbeck, A.; Norman, G.; Linnen, C. R.
10.1101/2022.10.11.511791 — evolutionary biology — Posted on 2022-10-14
2482 ULTRAFAST STRUCTURAL CHANGES DIRECT THE FIRST MOLECULAR EVENTS OF VISION
Gruhl, T.; Weinert, T.; Rodrigues, M.; Milne, C. J.; Ortolani, G.; Nass, K.; Nango, E.; Sen, S.; Johnson, P. J.; Cirelli, C.; Furrer, A.; Mous, S.; Skopintsev, P.; James, D.; Dworkowski, F.; Bath, P.; Kekilli, D.; Ozerov, D.; Tanaka, R.; Glover, H.; Bacellar, C.; Brunle, S.; Casadei, C. M.; Diethelm, A. D.; Gashi, D.; Gotthard, G.; Guixa-Gonzalez, R.; Joti, Y.; Kabanova, V.; Knopp, G.; Lesca, E.; Ma, P.; Martiel, I.; Muhle, J.; Owada, S.; Pamula, F.; Sarabi, D.; Tejero, O.; Tsai, C.-J.; Varma, N.; Wach, A.; Boutet, S.; Tono, K.; Nogly, P.; Deupi, X.; Iwata, S.; Neutze, R.; Standfuss, J.; Scher
10.1101/2022.10.14.511948 — biochemistry — Posted on 2022-10-14
2483 Independent innexin radiation shaped signaling in ctenophores.
Ortiz, J.; Bobkov, Y.; DeBiasse, M.; Mitchell, D. G.; Edgar, A.; Martindale, M. Q.; Moss, A. G.; Babonis, L. S.; Ryan, J. F.
10.1101/2022.10.11.511657 — evolutionary biology — Posted on 2022-10-14
2484 Structural analysis shows that the BIR2 domain of E3 ligase XIAP binds across the RIP2 kinase dimer interface
Lethier, M.; Hons, M.; Favier, A.; Brutscher, B.; Boeri Erba, E.; Cusack, S.; Pellegrini, E.
10.1101/2022.10.14.512215 — biochemistry — Posted on 2022-10-14
2489 DNA transposons of maT family in the Cnidaria
Puzakov, M. V.; Puzakova, L. V.; Cheresiz, S. V.; Shi, S.
10.1101/2022.10.13.512200 — evolutionary biology — Posted on 2022-10-14
2492 Genomic signals of local adaptation and hybridization in Asian white birch
Nocchi, G.; Wang, J.; Yang, L.; Ding, J.; Gao, Y.; Buggs, R. J. A.; Wang, N.
10.1101/2022.07.01.498522 — evolutionary biology — Posted on 2022-10-14
2493 The price of defence: toxins, visual signals and oxidative state in an aposematic butterfly
Blount, J. D.; Rowland, H. M.; Mitchell, C.; Speed, M. P.; Ruxton, G. D.; Endler, J. A.; Brower, L. P.
10.1101/2021.12.08.471400 — evolutionary biology — Posted on 2022-10-15
2496 Allee effects mediate the impact of land-use change on the thermal niche of social species
Chan, S.-F.; Rubenstein, D. R.; Wang, T.-W.; Chen, Y.-Y.; Chen, I.-C.; Ni, D.-Z.; Shih, W.-K.; Shen, S.-F.
10.1101/2022.10.11.511768 — ecology — Posted on 2022-10-14
2498 Estimating abundance of a recovering transboundary brown bear population with capture-recapture models
Vanpe, C.; Piedallu, B.; Quenette, P.-Y.; Sentilles, J.; Queney, G.; Palazon, S.; Jordana, I. A.; Jato, R.; Irurtia, M. M. E.; de la Torre, J. S.; Gimenez, O.
10.1101/2021.12.08.471719 — ecology — Posted on 2022-10-14
2503 Multi-omics analyses identify transcription factor interplay in corneal epithelial fate determination and disease
Smits, J.; Cunha, D. L.; Qu, J.; Owen, N.; Latta, L.; Szentmary, N.; Seitz, B.; Roux, L. N.; Moosajee, M.; Aberdam, D.; van Heeringen, S. J.; Zhou, H.
10.1101/2022.07.13.499857 — developmental biology — Posted on 2022-10-14
2507 Machine-guided cell-fate engineering
Appleton, E. M.; Tao, J.; Fonseca, G. J.; Liu, S.; Glass, C. H.; Church, G. M.
10.1101/2022.10.14.512279 — developmental biology — Posted on 2022-10-14
2508 A stem cell zoo uncovers intracellular scaling of developmental tempo across mammals
Lazaro, J.; Costanzo, M.; Sanaki-Matsumiya, M.; Girardot, C.; Hayashi, M.; Hayashi, K.; Diecke, S.; Hildebrandt, T. B.; Lazzari, G.; Wu, J.; Petkov, S. G.; Behr, R.; Trivedi, V.; Matsuda, M.; Ebisuya, M.
10.1101/2022.10.13.512072 — developmental biology — Posted on 2022-10-14
2511 Chimeric 3D-gastruloids - a versatile tool for studies of mammalian peri-gastrulation development
Wehmeyer, A. E.; Schüle, K. M.; Conrad, A.; Schröder, C. M.; Probst, S.; Arnold, S. J.
10.1101/2022.05.25.493377 — developmental biology — Posted on 2022-10-14
2512 IRE-1α is a key switch of pyroptosis and necroptosis in mice by dominating Gasdermin D
Xin, Z.; Qing, Z.; Yong, L. D.; Meng, L. Y.; Qing, X.; Hong, L. X.; Wen, L.; Min, Z.; Li, L.; Lu, Y.; Cheng, J.; Chen, Y.
10.1101/2022.10.12.511926 — cell biology — Posted on 2022-10-14
2513 Muscle stem cell function is impaired in absence of Talpid3 - a gene required for primary cilia formation
Martinez-Heredia, V.; Blackwell, D.; Sebastian, S.; Pearson, T.; Mok, G. F.; Mincarelli, L.; Utting, C.; Folkes, L.; Poschl, E.; Macaulay, I. C.; Mayer, U. C.; Munsterberg, A. E.
10.1101/2022.10.14.512102 — cell biology — Posted on 2022-10-14
2514 The CRL4B E3 ligase regulates mitosis by recruiting phospho-specific DCAFs
Stier, A.; Gilberto, S.; Mohamed, W. I.; Helenius, J.; Mikicic, I.; Sajic, T.; Beli, P.; Mueller, D. J.; Peter, M.
10.1101/2022.10.14.512051 — cell biology — Posted on 2022-10-14
2516 A Leaky Human Colon Model Reveals Uncoupled Apical/Basal Cytotoxicity in Early Clostridioides difficile Toxin Exposure
Ok, M. T.; Liu, J.; Bliton, R. J.; Hinesley, C. M.; San Pedro, E. E. T.; Breau, K. A.; Gomez-Martinez, I.; Burclaff, J.; Magness, S. T.
10.1101/2022.10.13.511617 — cell biology — Posted on 2022-10-14
2518 Peritubular macrophages phagocyte remains of undifferentiated spermatogonia in mouse testis
Lopez, L. A.; Marra, M. F.; Ibanez, J.; Millan, M. E.; Freites, C. L.; Fernandez, D.
10.1101/2022.10.14.512240 — cell biology — Posted on 2022-10-14
2521 Atf3 defines a population of pulmonary endothelial cells essential for lung regeneration
Niethamer, T. K.; Levin, L. I.; Morley, M. P.; Babu, A.; Zhou, S.; Morrisey, E. E.
10.1101/2022.10.14.512212 — cell biology — Posted on 2022-10-14
2524 The tendon interfascicular basement membrane provides a vascular niche for CD146+ pericyte cell subpopulations
MARR, N.; ZAMBOULIS, D. E.; WERLING, D.; FELDER, A. A.; DUDHIA, J.; PITSILLIDES, A. A.; THORPE, C. T.
10.1101/2022.10.14.512258 — cell biology — Posted on 2022-10-14
2525 Identifying human islet microRNAs associated with donor sex, age and body mass index
Wong, W. K.; Joglekar, M. V.; Cheng, F.; Jiang, G.; Sorensen, A. E.; Chew, Y. V.; Loudovaris, T.; Thomas, H. E.; Ma, R. C.; Hawthorne, W. J.; Dalgaard, L. T.; Hardikar, A. A.
10.1101/2022.10.14.512222 — cell biology — Posted on 2022-10-14
2530 DeepST: A novel graph self-supervised contrastive learning method for spatially informed clustering, integration, and deconvolution of spatial transcriptomics
Long, Y.; Ang, K. S.; Li, M.; Chong, K. L. K.; Sethi, R.; Zhong, C.; Xu, H.; Ong, Z.; Sachaphibulkij, K.; Chen, A.; Li, Z.; Fu, H.; Wu, M.; Lim, H. K. L.; Liu, L.; Chen, J.
10.1101/2022.08.02.502407 — bioinformatics — Posted on 2022-10-14
2533 Fast4DReg: Fast registration of 4D microscopy datasets
Pylvänäinen, J.; Laine, R.; Saraiva, B.; Ghimire, S.; Follain, G.; Henriques, R.; Jacquemet, G.
10.1101/2022.08.22.504744 — bioinformatics — Posted on 2022-10-14
2534 Disinhibition of the orbitofrontal cortex biases decision making in obesity
Seabrook, L. T.; Naef, L.; Baimel, C.; Judge, A. K.; Kenney, T.; Ellis, M.; Tayyab, T.; Armstrong, M.; Qiao, M.; Floresco, S. B.; Borgland, S. L.
10.1101/2020.04.02.022681 — neuroscience — Posted on 2022-10-14
2536 Design of novel Cyanovirin-N variants by modulation of binding dynamics through distal mutations
Kazan, I. C.; Sharma, P.; Rahman, M. I.; Bobkov, A. A.; Fromme, R.; Ghirlanda, G.; Ozkan, S. B.
10.1101/2020.12.21.423842 — biophysics — Posted on 2022-10-14
2538 Deep Learning Based Registration of Serial Whole-slide Histopathology Images in Different Stains
Roy, M.; Wang, F.; Teodoro, G.; Bhattarai, S.; Bhargava, M.; Rekha, T. S.; Aneja, R.; Kong, J.
10.1101/2022.05.31.494254 — bioinformatics — Posted on 2022-10-14
2540 The Human Pangenome's sequence conservation reveals a landscape of polymorphic structural variations
Lee, H.; Greer, S. U.; Pavlichin, D. S.; Hughes, C.; Zhou, B.; Weissman, T.; Ji, H. P.
10.1101/2022.10.06.511239 — genomics — Posted on 2022-10-13
2541 Sex differences in inter-individual gene expression variability across human tissues
Khodursky, S.; Jiang, C. S.; Zheng, E. B.; Vaughan, R.; Schrider, D. R.; Zhao, L.
10.1101/2022.08.09.503366 — evolutionary biology — Posted on 2022-10-13
2542 Lifespan Extension in Female Mice By Early, Transient Exposure to Adult Female Olfactory Cues
Garratt, M.; Erturk, I.; Alonso, R.; Zufall, F.; Leinders-Zufall, T.; Pletcher, S.; Miller, R.
10.1101/2022.10.07.511218 — evolutionary biology — Posted on 2022-10-14
2544 Artisanal and farmers bread making practices differently shape fungal species community composition in French sourdoughs
Michel, E.; Masson, E.; Bubbendorf, S.; Lapicque, L.; Nidelet, T.; Segond, D.; Guezenec, S.; Marlin, T.; Devillers, H.; Rue, O.; Onno, B.; Legrand, J.; Sicard, D.
10.1101/679472 — ecology — Posted on 2022-10-13
2545 The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia
Shinde, S. R.; Mick, D. U.; Aoki, E.; Rodrigues, R. B.; Gygi, S. P.; Nachury, M. V.
10.1101/2022.09.23.509287 — cell biology — Posted on 2022-10-13
2549 Comparative genomics of Streptococcus oralis identifies large scale homologous recombination and a genetic variant associated with infection
Joyce, L. R.; Youngblom, M. A.; Cormaty, H.; Gartstein, E.; Barber, K. E.; Akins, R. L.; Pepperell, C. S.; Palmer, K. L.
10.1101/2022.08.05.502949 — microbiology — Posted on 2022-10-13
2550 Brain state and cortical layer-specific mechanisms underlying perception at threshold
Morton, M. P.; Denagamage, S.; Blume, I. J.; Reynolds, J. H.; Jadi, M. P.; Nandy, A. S.
10.1101/2021.11.16.468866 — neuroscience — Posted on 2022-10-13
2552 Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer
Plattner, C.; Lamberti, G.; Blattmann, P.; Kirchmair, A.; Rieder, D.; Loncova, Z.; Sturm, G.; Scheidl, S.; Ijsselsteijn, M. E.; Fotakis, G.; Noureen, A.; Lisandrelli, R.; Boeck, N.; Nemati, N.; Krogsdam, A.; Daum, S.; Finotello, F. E.; Somarakis, A.; Schaefer, A.; Wilflingseder, D.; Gonzalez Acera, M.; Oefner, D.; Huber, L. A.; Clevers, H.; Becker, C.; Farin, H. F.; Greten, F. R.; Aebersold, R.; da Cunha Carvalho de Miranda, N. F.; Trajanoski, Z.
10.1101/2022.09.16.508204 — cancer biology — Posted on 2022-10-13
2553 Remodeling of yeast vacuole membrane lipidomes from the log (1-phase) to stationary stage (2-phases)
Reinhard, J.; Leveille, C. L.; Cornell, C.; Merz, A. J.; Klose, C.; Ernst, R.; Keller, S. L.
10.1101/2022.10.11.511736 — biophysics — Posted on 2022-10-13
2554 SOLID: Soft-lithography on SLA 3D printed moulds for fast, versatile, and accessible high-resolution fabrication of customised multiscale cell culture devices with complex designs
Hagemann, C.; Bailey, M. C. D.; Khokhar, N.; Lionello, V. M.; Suklai, P.; Moreno-Gonzalez, C.; O'Toole, K.; Konstantinou, G.; Joshi, S.; Giagnorio, E.; Bergholt, M.; Imbert, A.; Tedesco, F. S.; Serio, A.
10.1101/2022.02.22.481424 — bioengineering — Posted on 2022-10-13
2555 Optical Genome and Epigenome Mapping of Clear Cell Renal Cell Carcinoma
Margalit, S.; Tulpova, Z.; Michaeli, Y.; Detinis Zur, T.; Deek, J.; Louzoun-Zada, S.; Nifker, G.; Grunwald, A.; Scher, Y.; Schütz, L.; Weinhold, E.; Gnatek, Y.; Omer, D.; Dekel, B.; Friedman, E.; Ebenstein, Y.
10.1101/2022.10.11.511152 — genomics — Posted on 2022-10-13
2557 Stress-Induced Mucosal Layer Disruption Drives Gut Dysbiosis and Depressive-like Behaviors
Rivet-Noor, C.; Merchak, A. R.; Render, C.; Beiter, R. M.; Brown, R.; Slogar, E.; Keeler, A.; Moreau, G. B.; Li, S.; Olgun, D.; Phan, T. M. H.; Shin, J.-B.; Deppmann, C. D.; Gaultier, A.
10.1101/2022.10.13.512135 — microbiology — Posted on 2022-10-13
2558 Enterotoxigenic Escherichia coli heat-labile toxin drives enteropathic changes in small 1intestinal epithelia
Sheikh, A.; Tumala, B.; Vickers, T. J.; Martin, J. C.; Rosa, B. A.; Sabui, S.; Simoes, R. D.; Mitreva, M.; Storer, C.; Tyksen, E.; Head, R. D.; Beatty, W.; Said, H. M.; Fleckenstein, J. M.
10.1101/2022.08.24.504189 — microbiology — Posted on 2022-10-13
2559 Cytotoxic CD4 Development Requires CD4 Effectors to Concurrently Recognize Local Antigen and Encounter Infection-Induced IL-15
Devarajan, P.; Vong, A. M.; Castonguay, C. H.; Silverstein, N. J.; Bautista, B. L.; Kugler-Umana, O.; Kelly, K. A.; Luban, J.; Swain, S. L.
10.1101/2020.09.03.281998 — immunology — Posted on 2022-10-13
2562 High-Efficiency Pharmacogenetic Ablation of Oligodendrocyte Progenitor Cells in the Adult Mouse CNS
Xing, Y. L.; Poh, J.; Chuang, B. H. A.; Moradi, K.; Mitew, S.; Richardson, W. D.; Kilpatrick, T. J.; Osanai, Y.; Merson, T. D.
10.1101/2021.05.13.443012 — neuroscience — Posted on 2022-10-13
2563 Neural systems underlying RDoC social constructs: An activation likelihood estimation meta-analysis
Lobo, R. P.; Bottenhorn, K. L.; Riedel, M. C.; Toma, A. I.; Hare, M. M.; Smith, D. D.; Moor, A. C.; Cowan, I. K.; Valdes, J. A.; Bartley, J. E.; Salo, T.; Boeving, E. R.; Pankey, B.; Sutherland, M. T.; Musser, E. D.; Laird, A. R.
10.1101/2022.04.04.487016 — neuroscience — Posted on 2022-10-13
2564 A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during ageing and in Alzheimer's disease
Jones, M. E.; Buechler, J.; Dufor, T.; Palomer, E.; Teo, S.; Martin, N.; Boroviak, K.; Metzakopian, E.; Gibb, A.; Salinas, P. C.
10.1101/2022.04.06.487208 — neuroscience — Posted on 2022-10-13
2565 Population Transcriptome and Phenotype Reveal that the Rht-D1b Contribute a Larger Seedling Roots to Modern Wheat Cultivars
Wang, X.; Zhao, P.; Guo, X.; Liu, Z.; Ma, X.; Zhao, Y.; Lai, X.; Huang, L.; Wang, W.; Han, D.; Kang, Z.; Xu, S.
10.1101/2022.06.02.494553 — plant biology — Posted on 2022-10-13
2569 A quantitative map of nuclear pore assembly reveals two distinct mechanisms
Otsuka, S.; Tempkin, J. O. B.; Zhang, W.; Politi, A. Z.; Rybina, A.; Hossain, M. J.; Kueblbeck, M.; Callegari, A.; Koch, B.; Morero, N. R.; Sali, A.; Ellenberg, J.
10.1101/2021.05.17.444137 — cell biology — Posted on 2022-10-13
2570 Midbody proteins display distinct temporal dynamics during cytokinesis
Halcrow, E. F. J.; Mazza, R.; Diversi, A.; Enright, A.; D'Avino, P. P.
10.1101/2022.10.03.510602 — cell biology — Posted on 2022-10-13
2572 SARS-CoV-2 infection in domestic rats after transmission from their infected owner
Montagutelli, X.; Decaudin, B.; Beretta, M.; Mouquet, H.; Simon-Loriere, E.
10.1101/2022.10.13.512053 — microbiology — Posted on 2022-10-13
2575 Water mass age structures the auxiliary metabolic gene content of free-living and particle-attached deep ocean viral communities
Coutinho, F. H.; Silveira, C. B.; Sebastian, M.; Sanchez, P.; Duarte, C. M.; Vaque, D.; Gasol, J. M.; Acinas, S. G.
10.1101/2022.10.13.512062 — microbiology — Posted on 2022-10-13
2579 An RNA modification enzyme directly senses reactive oxygen species for translational regulation in Enterococcus faecalis
Lee, W. L.; Sinha, A.; Lam, L. N.; Loo, H. L.; Liang, J.; Ho, P.; Liang, C.; Chan, C.; Begley, T.; Kline, K. A.; Dedon, P.
10.1101/2022.10.12.511899 — microbiology — Posted on 2022-10-13
2581 In vitro and in vivo evaluation of the biofilm-degrading Pseudomonas phage Motto, as a candidate for phage therapy
Manohar, P.; Loh, B.; Turner, D.; Ramasamy, T.; Mathankumar, M.; Elangovan, N.; Nachimuthu, R.; Leptihn, S.
10.1101/2022.10.12.512010 — microbiology — Posted on 2022-10-13
2584 A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike
Dadonaite, B.; Crawford, K. H.; Radford, C. E.; Farrell, A. G.; Yu, T. C.; Hannon, W. W.; Zhou, P.; Andrabi, R.; Burton, D. R.; Liu, L.; Ho, D. D.; Neher, R. A.; Bloom, J. D.
10.1101/2022.10.13.512056 — microbiology — Posted on 2022-10-13
2585 Data Descriptor: Human whole exome genotype data for Alzheimer's Disease
Leung, Y. Y.; Naj, A. C.; Chou, Y.-F.; Valladares, O.; Wheeler, N.; Lin, H.; Gangadharan, P.; Qu, L.; Clark, K.; Cantwell, L.; Nicaretta, H.; the Alzheimer's Disease Sequencing Project, ; Seshadri, S.; Brkanac, Z.; Cruchaga, C.; Pericak-Vance, M. A.; Mayeux, R.; Kuzma, A. B.; Lee, W.-P.; Bush, W. S.; DeStefano, A. L.; Martin, E.; Schellenberg, G. D.; Wang, L.-S.
10.1101/2022.10.11.511653 — genetics — Posted on 2022-10-13
2586 Endosomes deliver ceramide phosphoethanolamine with unique acyl chain anchors to the cleavage furrow during male meiotic cytokinesis
KUNDURI, G.; Le, S.-H.; Baena, V.; Vijaykrishna, N.; Harned, A.; Nagashima, K.; Blankenberg, D.; Yoshihiro, I.; Narayan, K.; Bamba, T.; Acharya, U.; Acharya, J.
10.1101/2022.03.14.484204 — cell biology — Posted on 2022-10-13
2587 Phosphorylation dynamics in a flg22-induced, heterotrimeric G-protein dependent signaling network in Arabidopsis thaliana reveals a candidate PP2A phosphatase involved in AtRGS1 trafficking
Watkins, J. M.; Clark, N. M.; Song, G.; Oliveira, C. C.; Mishra, B.; Brachova, L.; Siefert, C. M.; Mitchell, M. S.; dos Reis, P. B.; Urano, D.; Mukhtar, S.; Walley, J. W.; Jones, A. M.
10.1101/2021.12.07.471565 — cell biology — Posted on 2022-10-13
2590 ERK3/MAPK6 dictates Cdc42/Rac1 activity and ARP2/3-dependent actin polymerization
Bogucka-Janczi, K.; Harms, G.; May-Coissieux, M.; Bentires-Alj, M.; Thiede, B.; Rajalingam, K.
10.1101/2022.10.12.511969 — cell biology — Posted on 2022-10-13
2594 Single-cell analysis characterizes non-enhancing region of recurrent high-grade glioma
Patel, K. S.; Tessema, K. K.; Kawaguchi, R.; Alvarado, A. G.; Muthukrishnan, S. D. D.; Hagiwara, A.; Swarup, V.; Liau, L. M.; Wang, A. C.; Yong, W.; Geschwind, D.; Nakano, I.; Goldman, S.; Everson, R.; Ellingson, B.; Kornblum, H.
10.1101/2022.10.10.511639 — neuroscience — Posted on 2022-10-13
2595 Physics-based Deep Learning for Imaging Neuronal Activity via Two-photon and Light Field Microscopy
Verinaz-Jadan, H.; Howe, C. L.; Song, P.; Lesept, F.; Kittler, J.; Foust, A. J.; Dragotti, P. L.
10.1101/2022.10.11.511633 — neuroscience — Posted on 2022-10-13
2604 Advanced physiological maturation of iPSC-derived human cardiomyocytes using an algorithm-directed optimization of defined media components
Callaghan, N. I.; Durland, L. J.; Chen, W.; Kuzmanov, U.; Miranda, M. Z.; Mirzaei, Z.; Ireland, R. G.; Wang, E. Y.; Wagner, K.; Kim, M. M.; Audet, J.; Santerre, P.; Gramolini, A. O.; Billia, F.; Radisic, M.; Ellis, J.; Mital, S.; Backx, P. H.; Simmons, C. A.
10.1101/2022.10.10.507929 — bioengineering — Posted on 2022-10-13
2607 Evidence of backcross inviability and mitochondrial DNA paternal leakage in sea turtle hybrids
Vilaca, S.; Maroso, F.; Lara, P.; de Thoisy, B.; Chevallier, D.; Arantes, L. S.; Bertorelle, G.; Mazzoni, C.
10.1101/2022.10.10.511144 — evolutionary biology — Posted on 2022-10-13
2610 Pangenome-based dynamic trajectories of intracellular gene transfers in Poaceae unveil a high rate of unceasing integration and selective retention in Triticeae
Chen, Y.; Guo, Y.; Xie, X.; Wang, Z.; Miao, L.; Yang, Z.; Jiao, Y.; Xie, C.; Liu, J.; Hu, Z.; Xin, M.; Yao, Y.; Ni, Z.; Sun, Q.; Peng, H.; Guo, W.
10.1101/2022.10.11.511703 — evolutionary biology — Posted on 2022-10-13
2613 OPTIMIZED NEURON TRACING USING POST HOC REANALYSIS
Azzouz, S.; Walker, L. A.; Doerner, A.; Geisel, K.; Rodriguez-Rivera, A. K.; Li, Y.; Roossien, D. H.; Cai, D.
10.1101/2022.10.10.511642 — neuroscience — Posted on 2022-10-13
2616 Subcortical circuit dysfunctions delay perceptual decision-making in autism models
Burnett, L. E.; Koppensteiner, P.; Symonova, O.; Masson, T.; Vega-Zuniga, T.; Contreras, X.; Ruelicke, T.; Shigemoto, R.; Novarino, G.; Joesch, M.
10.1101/2022.10.11.511691 — neuroscience — Posted on 2022-10-13
2617 Decoding brain basis of laughter and crying in natural scenes.
Nummenmaa, L.; Malen, T.; Nazari-Farsani, S.; Seppala, K.; Sun, L.; Karlsson, H.; Hudson, M.; Hirvonen, J.; Sams, M.; Scott, S. K.; Putkinen, V. J.
10.1101/2022.10.11.511708 — neuroscience — Posted on 2022-10-13
2618 The metabolite alpha-ketobutyrate increases health and life spans by activating AMPK
Chen, C.; Lomenick, B.; Chai, M.; Huang, W.; Chu, J.; Vergnes, L.; Johnson, R. O.; Vashisht, A. A.; Chin, R. M.; Dix, M. M.; Simon, G.; Fu, X.; Link, J. C.; Hwang, H.; Yin, X.; de Barros, S. C.; Braas, D.; Kim, N. H.; Wang, Y.; Dubinett, S. M.; Teitell, M. A.; Fiehn, O.; Jiang, M.; Cravatt, B. F.; Wohlschlegel, J. A.; Loo, J. A.; Reue, K.; Huang, J.
10.1101/2022.10.10.511641 — physiology — Posted on 2022-10-13
2621 An improved comprehensive strategy for deep and quantitative N-glycomics based on optimization of sample preparation, isotope-based data quality control and quantification, new N-glycan libraries and new algorithms
Guan, Y.; Hu, J.; Cao, W.; Cui, W.; Yang, F.; Krisp, C.; Lin, L.; Zhang, M.; Voss, H.; Schuster, R.; Yan, G.; Fuh, M. M.; Thaysen-Andersen, M.; H. Packer, N.; Shen, H.; Yang, P.; Schlüter, H.
10.1101/2020.10.15.340638 — biochemistry — Posted on 2022-10-13
2623 The establishment and transmission of novel foraging techniques indicates a capacity for culture in bumblebees (Bombus terrestris).
Bridges, A. D.; MaBouDi, H.; Procenko, O.; Lockwood, C.; Mohammed, Y.; Kowalewska, A.; Romero Gonzalez, J. E.; Woodgate, J. L.; Chittka, L.
10.1101/2022.10.10.511574 — animal behavior and cognition — Posted on 2022-10-13
2624 Developmental Validation of the Illumina Infinium Assay using the Global Screening Array (GSA) on the iScan System for use in Forensic Laboratories
Russell, D. A.; Gorden, E. M.; Peck, M. A.; Neal, C. M.; Heaton, M. C.; Bouchet, J.; Koeppel, A. F.; Ciuzio, E.; Turner, S. D.; Reedy, C. R.
10.1101/2022.10.10.511614 — genomics — Posted on 2022-10-13
2627 Timing matters: Sex differences in acute and chronic outcomes following repetitive blast mild traumatic brain injury
Baskin, B. M.; Logsdon, A. F.; Lee, J. S.; Foresi, B. D.; Peskind, E.; Banks, W. A.; Cook, D. G.; Schindler, A. G.
10.1101/2022.10.11.511013 — neuroscience — Posted on 2022-10-13
2629 A Cre-Driver Rat Model for Anatomical and Functional Analysis of Glucagon (Gcg)-Expressing Cells in the Brain and Periphery
Zheng, H.; Lopez-Ferreras, L.; Krieger, J.-P.; Fasul, S.; Cea Salazar, V.; Valderrama Pena, N.; Skibicka, K. P.; Rinaman, L.
10.1101/2022.10.10.511573 — neuroscience — Posted on 2022-10-13
2630 COVFlow: virus phylodynamics analyses from selected SARS-CoV-2 sequences
Danesh, G.; Boennec, C.; Verdurme, L.; Roussel, M.; Trombert, S.; Visseaux, B.; Haim-Boukobza, S.; Alizon, S.
10.1101/2022.06.17.496544 — bioinformatics — Posted on 2022-10-13
2635 Inability to make facial expressions dampens emotion perception.
Japee, S.; Jordan, J.; Licht, J.; Lokey, S.; Moebius Syndrome Research Consortium, ; Chen, G.; Snow, J.; Jabs, E. W.; Webb, B. D.; Engle, E. C.; Manoli, I.; Baker, C.; Ungerleider, L. G.
10.1101/2022.10.11.510399 — neuroscience — Posted on 2022-10-13
2637 Tripartite interactions between filamentous Pf4 bacteriophage, Pseudomonas aeruginosa, and bacterivorous nematodes
Schwartzkopf, C. M.; Robinson, A. J.; Ellenbecker, M.; Faith, D. R.; Brooks, D. M.; Lewerke, L.; Voronina, E.; Dandekar, A. A.; Secor, P. R.
10.1101/2022.10.11.511824 — microbiology — Posted on 2022-10-13
2638 Transcriptomic dissection of Intraepithelial Papillary Mucinous Neoplasms progression by spatial technologies identified novel markers of pancreatic carcinogenesis.
Agostini, A.; Piro, G.; Inzani, F.; Quero, G.; Esposito, A.; Caggiano, A.; Priori, L.; Larghi, A.; Alfieri, S.; Casolino, R.; Corbo, V.; Biankin, A.; Tortora, G.; Carbone, C.
10.1101/2022.10.12.511894 — cancer biology — Posted on 2022-10-13
2639 MR1-restricted T cell clonotypes are associated with 'resistance' to M.tuberculosis infection
Cross, D. L.; Layton, E. D.; Yu, K. K.; Smith, M. T.; Aguilar, M. S.; Li, S.; Mayanja-Kizza, H.; Stein, C. M.; Boom, W. H.; Hawn, T. R.; Bradley, P.; Newell, E.; Seshadri, C.
10.1101/2022.10.12.511825 — immunology — Posted on 2022-10-13
2641 An in vivo avian model of human melanoma to perform rapid and robust preclinical studies
Jarrosson, L.; Dalle, S.; Costechareyre, C.; Tang, Y.; Grimont, M.; Plaschka, M.; Lacourrege, M.; Teinturier, R.; Le Bouar, M.; Maucort-Boulch, D.; Eberhardt, A.; Castellani, V.; Caramel, J.; Delloye-Bourgeois, C.
10.1101/2022.10.12.511927 — cancer biology — Posted on 2022-10-13
2642 HDAC8-mediated inhibition of EP300 drives a neural crest-like transcriptional state that increases melanoma brain metastasis
Emmons, M. F.; Bennett, R. L.; Riva, A.; Zhang, C.; Macaulay, R.; Dupere-Richer, D.; Fang, B.; Seto, E.; Koomen, J.; Li, J.; Chen, A.; Forsyth, P.; Licht, J.; Smalley, K. S. M.
10.1101/2022.10.12.511971 — cancer biology — Posted on 2022-10-13
2643 Photodynamic therapy in colorectal cancer using photosensitizers functionalized by arene-ruthenium complexes
Massoud, J.; Pinon, A.; Gallardo-Villagran, M.; Paulus, L.; Antoun, S.; Diab-Assaf, M.; Therrien, B.; Liagre, B.
10.1101/2022.10.11.511744 — cancer biology — Posted on 2022-10-13
2644 Tissue-specific transcriptomes reveal mechanisms of microbiome regulation in an ancient fish
Thorstensen, M. J.; Weinrauch, A. M.; Bugg, W. S.; Jeffries, K. M.; Anderson, W. G.
10.1101/2022.10.12.511976 — zoology — Posted on 2022-10-13
2645 Semaphorin 4B is an ADAM17-cleaved inhibitor of adipocyte thermogenesis
Amin, A.; Badenes, M.; Tueshaus, J.; de Carvalho, E.; Burbridge, E.; Faisca, P.; Travnickova, K.; Barros, A.; Carobbio, S.; Domingos, P.; Vidal-Puig, A.; Moita, L. F.; Maguire, S.; Strisovsky, K.; Lichtenthaler, S. F.; Adrain, C.
10.1101/2022.10.11.511765 — physiology — Posted on 2022-10-13
2646 Extracellular vesicles from non-neuroendocrine SCLC cells promote adhesion and survival of neuroendocrine SCLC cells
Jimenez, L.; Stolzenbach, V.; Ozawa, P. M. M.; Ramirez-Solano, M. A.; Liu, Q.; Sage, J.; Weaver, A.
10.1101/2022.10.12.511984 — cancer biology — Posted on 2022-10-13
2647 HOXA9 forms a repressive complex with nuclear matrix-associated protein SAFB to maintain acute myeloid leukemia
Agrawal Singh, S.; Bagri, J.; Giotopoulos, G.; Azazi, D.; Horton, S. J.; Houghton, J. W.; Anand, S.; Bach, A. S.; Stedham, F.; Antrobus, R.; Vassiliou, G.; Sasca, D.; Yun, H.; Whetton, A.; Huntly, B. J. P.
10.1101/2022.10.12.511919 — cancer biology — Posted on 2022-10-13
2648 mTORC2 Interactome and Localization Determine Aggressiveness of High-Grade Glioma Cells through Association with Gelsolin
Chantaravisoot, N.; Wongkongkathep, P.; Kalpongnukul, N.; Pacharakullanon, N.; Kaewsapsak, P.; Ariyachet, C.; Loo, J. A.; Tamanoi, F.; Pisitkun, T.
10.1101/2022.10.12.511677 — cancer biology — Posted on 2022-10-13
2651 Specific Ethogram of the Mexican four-eyed octopus: Octopus maya.
Gonzalez-Navarrete, D. A.; Vergara-Ovalle, F.; Garcia-Andaluz, P.; Ayala-Guerrero, F.; Rosas, C.; Vazquez-Leon, P.; Paz-Trejo, D. B.; Sanchez-Castillo, H.
10.1101/2022.10.10.511610 — animal behavior and cognition — Posted on 2022-10-13
2653 How ancient forest fragmentation and riparian connectivity generate high levels of genetic diversity in a micro-endemic Malagasy tree
Salmona, J.; Dresen, A.; Ranaivoson, A. E.; Manzi, S.; Le Pors, B.; Hong-Wa, C.; Razanatsoa, J.; Andriaholinirina, N. V.; Rasoloharijaona, S.; Vavitsara, M.-E.; Besnard, G.
10.1101/2020.11.25.394544 — genomics — Posted on 2022-10-13
2655 Epidermis derived lactate promotes sterile inflammation by inducing metabolic rewiring in macrophages.
Ayyangar, U.; Karkhanis, A.; Tay, H.; Afandi, A. F. B.; Bhattacharjee, O.; Lee, S. H.; Chan, J.; Raghavan, S.
10.1101/2022.07.29.501937 — cell biology — Posted on 2022-10-13
2657 Evolutionary Diversification of Methanotrophic Ca. Methanophagales (ANME-1) and Their Expansive Virome
Laso-Perez, R.; Wu, F.; Cremiere, A.; Speth, D. R.; Magyar, J. S.; Krupovic, M.; Orphan, V. J.
10.1101/2022.07.04.498658 — microbiology — Posted on 2022-10-13
2658 Whole-brain multivariate hemodynamic deconvolution for multi-echo fMRI with stability selection
Urunuela, E.; Gonzalez-Castillo, J.; Zheng, C.; Bandettini, P.; Caballero Gaudes, C.
10.1101/2022.09.30.510299 — neuroscience — Posted on 2022-10-13
2661 Is brightfield all you need for mechanism of action prediction?
Gupta, A.; Harrison, P. J.; Wieslander, H.; Rietdijk, J.; Carreras-Puigvert, J.; Georgiev, P.; Wahlby, C.; Spjuth, O.; Sintorn, I.-M.
10.1101/2022.10.12.511869 — bioinformatics — Posted on 2022-10-13
2662 CRISPR-Cas phage defense systems and prophages in Candidatus Accumulibacter
Deng, X.; Yuan, J.; Chen, L.; Chen, H.; Wei, C.; Nielsen, P. H.; Wuertz, S.; Qiu, G.
10.1101/2022.10.12.504627 — bioinformatics — Posted on 2022-10-13
2663 Developing a standardized but extendable framework to increase the findability of infectious disease datasets
Tsueng, G.; Alvarado Cano, M. A.; Bento, J.; Czech, C.; Kang, M.; Pache, L.; Rasmussen, L. V.; Savidge, T. C.; Starren, J.; Wu, Q.; Xin, J.; Yeaman, M. R.; Zhou, X.; Su, A. I.; Wu, C.; Brown, L.; Shabman, R. S.; Hughes, L. D.; NIAID Systems Biology Data Dissemination Working Group,
10.1101/2022.10.10.511492 — bioinformatics — Posted on 2022-10-13
2664 Substrate selectivity of the PRDM9 lysine methyltransferase domain.
Hanquier, J. N.; Sanders, K.; Berryhill, C. A.; Sahoo, F. K.; Hudmon, A.; Vilseck, J. Z.; Cornett, E. M.
10.1101/2022.10.12.511945 — biochemistry — Posted on 2022-10-13
2666 A novel de novo FEM1C variant is linked to neurodevelopmental disorder with absent speech, pyramidal signs, and limb ataxia
Dubey, A. A.; Krygier, M.; Szulc, N. A.; Rutkowska, K.; Kosinska, J.; Pollak, A.; Rydzanicz, M.; Kmiec, T.; Mazurkiewicz-Beldzinska, M.; Pokrzywa, W.; Ploski, R.
10.1101/2022.04.24.489208 — genetics — Posted on 2022-10-13
2667 Representational dynamics of memories for real-life events
Jeunehomme, O.; Heinen, R.; Stawarczyk, D.; Axmacher, N.; D'Argembeau, A.
10.1101/2022.02.18.480992 — neuroscience — Posted on 2022-10-13
2671 Functional annotation of the animal genomes: an integrated annotation resource for the horse
Finno, C.; Peng, S.; Dahlgren, A. R.; Donnelly, C. G.; Hales, E. N.; Petersen, J. L.; Bellone, R. R.; Kalbfleisch, T.
10.1101/2022.10.11.511694 — genetics — Posted on 2022-10-13
2674 Plant height predicts leaf shape in palms (Arecaceae)
Jimenez, M. F. T.; Chazot, N.; Emilio, T.; Fredin, J. U.; Antonelli, A.; Faurby, S.; Bacon, C. D.
10.1101/2021.10.26.465896 — evolutionary biology — Posted on 2022-10-13
2678 The kleisin subunit controls the function of meiotic cohesins by determining the mode of DNA binding and differential regulation by SCC-2 and WAPL-1
Castellano-Pozo, M.; Sioutas, G.; Barroso, C.; Lopez-Jimenez, P.; Jaso-Tamame, A. L.; Crawley, O.; Shao, N.; Page, J.; Martinez-Perez, E.
10.1101/2022.10.12.511771 — cell biology — Posted on 2022-10-12
2679 Endosomal removal and disposal of dysfunctional, immunostimulatory mitochondrial DNA
Newman, L. E.; Tadepalle, N.; Novak, S. W.; Schiavon, C. R.; Rojas, G. R.; Chevez, J. A.; Lemersal, I.; Medina, M.; Rocha, S.; Towers, C. G.; Grotjahn, D. A.; Manor, U.; Shadel, G. S.
10.1101/2022.10.12.511955 — cell biology — Posted on 2022-10-12
2680 FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors
Pagan, J.; Nguyen-Dien, G.; Kozul, K.; Cui, Y.; Townsend, B.; Ooi, S. S.; Pagano, M.; Lazarou, M.; Taylor, R.; Collins, B. M.; Parton, R. G.; Kulkarni, P.; Carrodus, N.; Zuryn, S.; Millard, S.; Marzio, A.; Jones, M.
10.1101/2022.10.12.511867 — cell biology — Posted on 2022-10-12
2683 Structures of the holo CRISPR RNA-guided transposon integration complex
Park, J.-U.; Tsai, A. W.-L.; Rizo, A. N.; Truong, V. H.; Wellner, T. X.; Schargel, R. D.; Kellogg, E. H.
10.1101/2022.10.12.511933 — biophysics — Posted on 2022-10-12
2684 Remodeling of yeast vacuole membrane lipidomes from the log (1-phase) to stationary stage (2-phases)
Reinhard, J.; Leveille, C. L.; Cornell, C.; Merz, A. J.; Klose, C.; Ernst, R.; Keller, S. L.
10.1101/2022.10.11.511736 — biophysics — Posted on 2022-10-12
2685 The redlegged earth mite draft genome provides new insights into pesticide resistance evolution and demography in its invasive Australian range
Thia, J. A.; Korhonen, P. K.; Young, N. D.; Gasser, R. B.; Umina, P. A.; Yang, Q.; Edwards, O.; Walsh, T.; Hoffmann, A. A.
10.1101/2022.08.03.502713 — genomics — Posted on 2022-10-12
2691 IGFBP2 expressing midlobular hepatocytes preferentially contribute to liver homeostasis and regeneration
Lin, Y.-H.; Wei, Y.; Wang, Y.; Pagani, C.; Li, L.; Zhu, M.; Wang, Z.; Hsieh, M.-H.; Zhang, Y.; Sharma, T.; Wang, T.; Zhu, H.
10.1101/2022.10.12.511675 — developmental biology — Posted on 2022-10-12
2693 Development of novel cytoprotective small compounds inhibiting mitochondria-dependent apoptosis
Matsuyama, S.; Matsuyama, M.; Ortega, J.; Fedorov, Y.; Scott-McKean, J.; Muller-Greven, J.; Buck, M.; Adams, D.; Jastrzebska, B.; Greenlee, W.
10.1101/2022.10.12.511987 — cell biology — Posted on 2022-10-12
2695 Functionally distinct promoter classes initiate transcription via different mechanisms reflected in focused versus dispersed initiation patterns
Serebreni, L.; Pleyer, L.-M.; Haberle, V.; Hendy, O.; Vlasova, A.; Loubiere, V.; Nemcko, F.; Bergauer, K.; Roitinger, E.; Mechtler, K.; Stark, A.
10.1101/2022.09.30.509643 — molecular biology — Posted on 2022-10-12
2699 Ectopic FVIII expression and misfolding in hepatocytes as a cause for hepatocellular carcinoma
Kapelanski-Lamoureux, A.; Chen, Z.; Gao, Z.-h.; Deng, R.; Lazaris, A.; Lebeaupin, C.; Giles, L.; Malhotra, J.; Yong, J.; Zou, C.; de Jong, Y. P.; Metrakos, P.; Herzog, R. W.; Kaufman, R. J.
10.1101/2021.01.19.427220 — cancer biology — Posted on 2022-10-12
2701 GADMA2: more efficient and flexible demographic inference from genetic data
Noskova, E.; Abramov, N.; Iliutkin, S.; Sidorin, A.; Dobrynin, P.; Ulyantsev, V.
10.1101/2022.06.14.496083 — bioinformatics — Posted on 2022-10-12
2702 Pervasive tandem duplications and convergent evolution shape coral genomes
Noel, B.; Denoeud, F.; Rouan, A.; Buitrago-Lopez, C.; Capasso, L.; Poulain, J.; Boissin, E.; Pousse, M.; Da Silva, C.; Couloux, A.; Armstrong, E.; Carradec, Q.; Cruaud, C.; Labadie, K.; Le-Hoang, J.; Tambutte, S.; Barbe, V.; Moulin, C.; Bourdin, G.; Iwankow, G.; Romac, S.; Allemand, D.; Planes, S.; Gilson, E.; Zoccola, D.; Wincker, P.; Voolstra, C.; Aury, J.-M.
10.1101/2022.05.17.492263 — genomics — Posted on 2022-10-12
2706 Deep neural network automated segmentation of cellular structures in volume electron microscopy
Gallusser, B.; Maltese, G.; Di Caprio, G.; Vadakkan, T. J.; Sanyal, A.; Somerville, E.; Sahasrabudhe, M.; O'Connor, J.; Weigert, M.; Kirchhausen, T.
10.1101/2022.08.02.502534 — cell biology — Posted on 2022-10-12
2707 Structural polymorphism of amyloid fibrils in cardiac ATTR amyloidosis revealed by cryo-electron microscopy
Nguyen, B. A.; Afrin, S.; Singh, V.; Ahmed, Y.; Pedretti, R.; Fernandez Ramirez, M. d. C.; Benson, M. D.; Sawaya, M.; Singh, P.; Cao, Q.; Boyer, D.; Pope, A.; Wydorski, P. M.; Kumar, S.; Chhapra, F.; Eisenberg, D. S.; Saelices, L.
10.1101/2022.06.21.496949 — molecular biology — Posted on 2022-10-12
2709 Semantic novelty modulates neural responses to visual change across the human brain
Nentwich, M.; Leszczynski, M.; Russ, B. E.; Hirsch, L.; Markowitz, N.; Sapru, K.; Schroeder, C. E.; Mehta, A.; Bickel, S.; Parra, L. C.
10.1101/2022.06.20.496467 — neuroscience — Posted on 2022-10-12
2711 Evaluation of Transfer Learning Methods for Detecting Alzheimer's Disease with Brain MRI
Dhinagar, N. J.; Thomopoulos, S. I.; Rajagopalan, P.; Stripelis, D.; Ambite, J. L.; Steeg, G. V.; Thompson, P. M.
10.1101/2022.08.23.505030 — neuroscience — Posted on 2022-10-12
2712 Teaching a computer to assess hypnotic depth: A pilot study
Obukhov, N. V.; Naish, P. L. N.; Solnyshkina, I. E.; Siourdaki, T. G.; Martynov, I. A.
10.1101/2021.11.13.467562 — neuroscience — Posted on 2022-10-12
2714 Defining protein variant functions using high-complexity mutagenesis libraries and enhanced mutant detection software ASMv1.0
Yang, X.; Hong, A. L.; Sharpe, T.; Giacomelli, A. O.; Lintner, R. E.; Alan, D.; Green, T.; Hayes, T. K.; Piccioni, F.; Fritchman, B.; Kawabe, H.; Sawyer, E.; Sprenkle, L.; Lee, B. P.; Persky, N. S.; Brown, A.; Greulich, H.; Aguirre, A. J.; Meyerson, M.; Hahn, W. C.; Johannessen, C. M.; Root, D. E.
10.1101/2021.06.16.448102 — systems biology — Posted on 2022-10-12
2716 Morphology and gene expression profiling provide complementary information for mapping cell state
Way, G. P.; Natoli, T.; Adeboye, A.; Litichevskiy, L.; Yang, A. X.; Lu, X.; Caicedo, J.; Cimini, B. A.; Karhohs, K.; Logan, D. J.; Rohban, M.; Kost-Alimova, M.; Hartland, K.; Bornholdt, M.; Chandrasekaran, N.; Haghighi, M.; Singh, S.; Subramanian, A.; Carpenter, A. E.
10.1101/2021.10.21.465335 — bioinformatics — Posted on 2022-10-12
2717 Structural and biochemical insights into heterotetramer formation between human oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator
Tariq, M.; Ikeya, T.; Togashi, N.; Fairall, L.; Bueno-Alejo, C.; Kamei, S.; Romartinez-Alonso, B.; Muro Campillo, M. A.; Hudson, A. J.; Ito, Y.; Schwabe, J. W.; Dominguez, C.; Tanaka, K.
10.1101/2022.10.10.511529 — biochemistry — Posted on 2022-10-12
2720 Importin alpha/βeta Promote Kif18B Microtubule Association to Spatially Control Microtubule Destabilization
Shrestha, S.; Ems-McClung, S. C.; Hazelbaker, M. A.; Yount, A. L.; Shaw, S. L.; Walczak, C.
10.1101/2022.03.30.486445 — cell biology — Posted on 2022-10-12
2721 RNA-binding protein Orb2 causes microcephaly and supports centrosome asymmetry in Drosophila neural stem cells
Robinson, B. V.; Buehler, J.; Hailstock, T.; Adebambo, T. H.; Fang, J.; Mehta, D. S.; Lerit, D.
10.1101/2021.11.23.469707 — cell biology — Posted on 2022-10-12
2722 The unifying catalytic mechanism of the RING-between-RING E3 ligase family
Wang, X. S.; Cotton, T. R.; Trevelyan, S. J.; Richardson, L. W.; Lee, W. T.; Silke, J.; Lechtenberg, B. C.
10.1101/2022.10.11.511834 — biochemistry — Posted on 2022-10-12
2724 Optical Genome and Epigenome Mapping of Clear Cell Renal Cell Carcinoma
Margalit, S.; Tulpova, Z.; Michaeli, Y.; Detinis Zur, T.; Deek, J.; Louzoun-Zada, S.; Grunwald, A.; Scher, Y.; Schutz, L.; Weinhold, E.; Gnatek, Y.; Over, D.; Dekel, B.; Friedman, E.; Ebenstein, Y.
10.1101/2022.10.11.511152 — genomics — Posted on 2022-10-12
2727 Engineering a Universal Dengue Virus Vaccine using a Virus-Like Particle Scaffold
Basore, D. A.; Barcellona, C. M.; Jordan, T. B.; Crone, D. E.; Isern, S.; Michael, S. F.; Bystroff, C.
10.1101/2022.10.11.511616 — molecular biology — Posted on 2022-10-12
2730 Spatial expression of an mRNA encoding Tie2-agonist in the capillary endothelium of the lung prevents pulmonary vascular leakage
Radloff, K.; Gutbier, B.; Dunne, C. M.; Moradian, H.; Gossen, M.; Ahrens, K. M.; Keller, L.; Wang, Y.; Moga, A.; Gkionis, L.; Keil, O.; Fehring, V.; Tondera, D.; Giese, K.; Kaufmann, J.; Witzenrath, M.
10.1101/2022.10.12.511878 — molecular biology — Posted on 2022-10-12
2731 Structural journey of an insecticidal pore-forming protein targeting western corn rootworm
Marini, G.; Poland, B.; Leininger, C.; Lukoyanova, N.; Spielbauer, D.; Barry, J.; Altier, D.; Lum, A.; Scolaro, E.; Perez Ortega, C.; Yalpani, N.; Sandahl, G.; Mabry, T.; Klever, J.; Nowatzki, T.; Zhao, J.-Z.; Sethi, A.; Kassa, A.; Crane, V.; Lu, A.; Nelson, M.; Eswar, N.; Topf, M.; Saibil, H.
10.1101/2022.10.12.511876 — molecular biology — Posted on 2022-10-12
2734 Model-driven approach for the production of butyrate from CO2/H2 by a novel co-culture of C. autoethanogenum and C. beijerinckii.
Benito-Vaquerizo, S.; Nouse, N.; Schaap, P. J.; Hugenholtz, J.; Brul, S.; Lopez-Contreras, A.; Martins dos Santos, V. A. P.; Suarez-Diez, M.
10.1101/2022.10.12.511882 — microbiology — Posted on 2022-10-12
2735 Permeation Across the Mycomembrane in Live Mycobacteria
Liu, Z.; Lepori, I.; Dalesandro, B. E.; Chordia, M. D.; Siegrist, M. S.; Pires, M.
10.1101/2022.10.12.509737 — microbiology — Posted on 2022-10-12
2739 Discrepancy between Mtb-specific IFN-γ and IgG responses in HIV-positive people with low CD4 counts.
Mthembu, M.; Bowman, K. A.; Davies, L. L.; Khuzwayo, S.; Mazibuko, L.; Bassett, T.; Ramjit, D.; Mhlane, Z.; Karim, F.; Alter, G.; Ndung'u, T.; Wong, E. B.
10.1101/2022.10.11.511821 — immunology — Posted on 2022-10-12
2740 Humanized CB1R and CB2R yeast biosensors enable facile screening of cannabinoid compounds
Mulvihill, C. J.; Lutgens, J.; Gollihar, J. D.; Bachanova, P.; Marcotte, E. M.; Ellington, A. D.; Gardner, E. C.
10.1101/2022.10.12.511978 — synthetic biology — Posted on 2022-10-12
2741 Discovering hub genes involved in the pathophysiological impact of COVID-19 on diabetes kidney disease by differential gene expression and interactome analysis
Osuna Martinez, U.; Avina-Padilla, K.; Olimon-Andalon, V.; Angulo, C.; Guadron-Llanos, A.; Rivas-Ferreira, J. C.; Urrea, F.; Calderon-Zamora, L.
10.1101/2022.10.11.511826 — bioinformatics — Posted on 2022-10-12
2742 Molecular evidence of widespread benzimidazole drug resistance in Ancylostoma caninum from domestic dogs throughout the USA and discovery of a novel isotype-1 β-tubulin benzimidazole resistance mutation.
Venkatesan, A.; Jimenez Castro, P. D.; Morosetti, A.; Horvath, H.; Chen, R.; Redman, E.; Dunn, K.; Collins, J. B.; Fraser, J. S.; Anderson, E. C.; Kaplan, R. M.; Gilleard, J. S.
10.1101/2022.10.12.511840 — genomics — Posted on 2022-10-12
2744 Alterations in platelet proteome signature and impaired platelet integrin αIIbβ3 activation in patients with COVID-19
Goudswaard, L. J.; Williams, C. M.; Khalil, J.; Burley, K. L.; Hamilton, F.; Arnold, D.; Milne, A.; Lewis, P. A.; Heesom, K. J.; Mundell, S. J.; Davidson, A. D.; Poole, A. W.; Hers, I.
10.1101/2022.10.12.511145 — cell biology — Posted on 2022-10-12
2748 Development of SARS-CoV-2 replicons for the ancestral virus and variant of concern Delta for antiviral screening.
Erdmann, M.; Kavanagh Williamson, M.; Jearanaiwitayakul, T.; Bazire, J.; Matthews, D. A.; Davidson, A. D.
10.1101/2022.10.11.511804 — microbiology — Posted on 2022-10-12
2749 The clock gene Per1 expression may exert diurnal control over hippocampal memory consolidation
Bellfy, L.; Smies, C. W.; Bernhardt, A. R.; Bodinayake, K. K.; Sebastian, A.; Stuart, E. M.; Wright, D. S.; Lo, C.-Y.; Murakami, S.; Boyd, H. M.; von Abo, M. J.; Albert, I.; Kwapis, J. L.
10.1101/2022.10.11.511798 — neuroscience — Posted on 2022-10-12
2750 Novel Pore Size-Controlled, Susceptibility Matched, 3D-Printed MRI Phantoms
Witherspoon, V.; Komlosh, M. E.; Benjamini, D.; Özarslan, E.; Lavrik, N.; Basser, P.
10.1101/2022.10.10.511634 — biophysics — Posted on 2022-10-12
2751 A key GPCR phosphorylation motif discovered in arrestin2-CCR5 phosphopeptide complexes
Isaikina, P.; Petrovic, I.; Jakob, R. P.; Sarma, P.; Ranjan, A.; Baruah, M.; Panwalkar, V.; Maier, T.; Shukla, A. K.; Grzesiek, S.
10.1101/2022.10.10.511578 — biophysics — Posted on 2022-10-12
2752 Structure of the Inmazeb cocktail and resistance to escape against Ebola virus
Rayaprolu, V.; Fulton, B.; Rafique, A.; Arturo, E.; Williams, D.; Hariharan, C.; Callaway, H.; Parvate, A.; Schendel, S. L.; Parekh, D.; Hui, S.; Shaffer, K.; Pascal, K. E.; Wloga, E.; Giordano, S.; Copin, R.; Franklin, M.; Boytz, R.; Donahue, C.; Davey, R.; Baum, A.; Kyratsous, C. A.; Saphire, E. O.
10.1101/2022.10.11.511805 — biophysics — Posted on 2022-10-12
2753 Stochastic chain termination in bacterial pilus assembly
Giese, C.; Puorger, C.; Ignatov, O.; Becarova, Z.; Weber, M.; Scharer, M.; Capitani, G.; Glockshuber, R.
10.1101/2022.10.11.511808 — biophysics — Posted on 2022-10-12
2757 Deep learning can predict multi-omic biomarkers from routine pathology images: A systematic large-scale study
Arslan, S.; Mehrotra, D.; Schmidt, J.; Geraldes, A.; Singhal, S.; Hense, J.; Li, X.; Bass, C.; Kather, J. N.; Pandya, P.; Raharja-Liu, P.
10.1101/2022.01.21.477189 — cancer biology — Posted on 2022-10-12
2758 Divergent TLR2 and TLR4 activation by fungal spores and species diversity in dust from waste-sorting plants
Afanou, K. A.; Mundra, S.; Estensmo, E. L.; Pedersen, I.; Liland, J. R.; Eriksen, E.; Graff, P.; Hildre, T. T.; Nordby, K.-C.; Straumfors, A.
10.1101/2022.10.10.511688 — microbiology — Posted on 2022-10-12
2759 Therapeutic trial of anle138b in mouse models of genetic prion disease
Vallabh, S. M.; Zou, D.; Pitstick, R.; O'Moore, J.; Peters, J.; Silvius, D.; Kriz, J.; Jackson, W. S.; Carlson, G. A.; Minikel, E. V.; Cabin, D. E.
10.1101/2022.10.11.511739 — neuroscience — Posted on 2022-10-12
2760 A novel micro-ECoG recording method for recording multisensory neural activity from the parietal to temporal cortices in mice
Setogawa, S.; Kanda, R.; Tada, S.; Saitoh, Y.; Ishikawa, M.; Nakada, S.; Seki, F.; Hikishima, K.; Matsumoto, H.; Mizuseki, K.; Fukayama, O.; Osanai, M.; Sekiguchi, H.; Ohkawa, N.
10.1101/2022.10.01.510247 — neuroscience — Posted on 2022-10-12
2762 Z-REX uncovers a bifurcation in function of Keap1 paralogs
Van Hall-Beauvais, A.; Poganik, J. R.; Huang, K.-T.; Parvez, S.; Zhao, Y.; Lin, H.-Y.; Liu, X.; Long, M. J. C.; Aye, Y.
10.1101/2022.10.10.511579 — pharmacology and toxicology — Posted on 2022-10-12
2764 A conserved and tunable mechanism for the temperature-controlled condensation of the translation factor Ded1p
Jegers, C.; Franzmann, T. M.; Hübner, J.; Schneider, J.; Landerer, C.; Wittmann, S.; Toth-Petroczy, A.; Sprangers, R.; Hyman, A. A.; Alberti, S.
10.1101/2022.10.11.511767 — biochemistry — Posted on 2022-10-12
2766 SAGA histone acetyltransferase module facilitates chromatin accessibility to SMC5/6
Mahrik, L.; Stefanovie, B.; Maresova, A.; Princova, J.; Kolesar, P.; Lelkes, E.; Helmlinger, D.; Prevorovsky, M.; Palecek, J. J.
10.1101/2022.09.24.508842 — genetics — Posted on 2022-10-12
2767 Ritualistic use of ayahuasca enhances a shared functional connectome identity with others.
Mallaroni, P.; Mason, N. L.; Kloft, L.; Reckweg, J. T.; van Oorsouw, K.; Toennes, S. W.; Tolle, H. M.; Amico, E.; Ramaekers, J. G.
10.1101/2022.10.07.511268 — neuroscience — Posted on 2022-10-12
2769 P-TEFb promotes cell survival upon p53 activation by suppressing intrinsic apoptosis pathway
Wang, Z.; Macakova, M.; Bugai, A.; Kuznetsov, S. G.; Hassinen, A.; Lenasi, T.; Potdar, S.; Friedel, C.; Barboric, M.
10.1101/2022.05.29.493929 — biochemistry — Posted on 2022-10-12
2770 Exploration of the single-cell transcriptomic landscape identifies aberrant glomerular cell crosstalk in a murine model of WT1 kidney disease
Chandler, J. C.; Jafree, D. J.; Malik, S.; Pomeranz, G.; Ball, M.; Kolatsi-Joannou, M.; Piapi, A.; Mason, W. J.; Woolf, A. S.; Winyard, P. J.; Mason, A. S.; Waters, A. M.; Long, D. A.
10.1101/2022.10.11.511555 — cell biology — Posted on 2022-10-12
2772 Maximum a posteriori natural scene reconstruction from retinal ganglion cells with deep denoiser priors
Wu, E. G.; Brackbill, N.; Sher, A.; Litke, A. M.; Simoncelli, E. P.; Chichilnisky, E. J.
10.1101/2022.05.19.492737 — neuroscience — Posted on 2022-10-12
2773 Functional screens of barcoded expression libraries uncover new gene functions in carbon utilization among gut Bacteroidales
Huang, Y. Y.; Price, M. N.; Hung, A.; Gal-Oz, O.; Ho, D.; Carion, H.; Deutschbauer, A. M.; Arkin, A. P.
10.1101/2022.10.10.511384 — microbiology — Posted on 2022-10-11
2774 Mechanism of dual pharmacological correction and potentiation of human CFTR
Wang, C.; Yang, Z.; Loughlin, B. J.; Xu, H.; Veit, G.; Vorobiev, S.; Clarke, O. B.; Jiang, F.; Li, Y.; Singh, S.; Rich, Z.; Menten, E. R.; Grassucci, R. A.; Wang, W.; Mezzell, A.; Fu, Z.; Wong, K.-H.; Wang, J.; Wetmore, D. R.; Sutton, R. B.; Brouillette, C. G.; Urbatsch, I. L.; Kappes, J. C.; Lukacs, G. L.; Frank, J.; Hunt, J. F.
10.1101/2022.10.10.510913 — biophysics — Posted on 2022-10-11
2775 Thresholding Gini Variable Importance with a single trained Random Forest: An Empirical Bayes Approach
Dunne, R. A.; Reguant, R.; Ramarao-Milne, P.; Szul, P.; Sng, L.; Lundberg, M.; Twine, N. A.; Bauer, D. C.
10.1101/2022.04.06.487300 — bioinformatics — Posted on 2022-10-11
2776 Nicotinamide mononucleotide (NMN) de-amidation by host-microbiome interactions
Kim, L.-J.; Chalmers, T. J.; Madawala, R.; Smith, G. C.; Das, A.; Poon, E. W. K.; Wang, J.; Tucker, S. P.; Sinclair, D. A.; Quek, L.-E.; Wu, L. E.
10.1101/2020.09.10.289561 — biochemistry — Posted on 2022-10-11
2777 Cilium proteomics reveals Numb as a positive regulator of the Hedgehog signaling pathway
Liu, X.; Yam, P.; Chen, W.-J.; Schlienger, S.; Torres Gutierrez, O.; Cai, E.; Zhang, J.; Ting, A. Y.; Branon, T. C.; Cayouette, M.; Charron, F.; Ge, X.
10.1101/2022.10.10.511655 — cell biology — Posted on 2022-10-11
2778 Multi-omic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation
Erickson, E.; You, I.; Perry, G.; Dugourd, A.; Donovan, K.; Crafter, C.; Johannes, J.; Williamson, S.; Moss, J.; Ros, S.; Ziegler, R.; Barry, S.; Fischer, E.; Gray, N.; Madsen, R.; Toker, A.
10.1101/2022.10.11.511726 — cancer biology — Posted on 2022-10-11
2779 Zasp52 strengthens whole embryo tissue integrity through supracellular actomyosin networks
Ashour, D. J.; Durney, C. H.; Planelles-Herrero, V. J.; Stevens, T. J.; Feng, J. J.; Röper, K.
10.1101/2022.10.11.511783 — developmental biology — Posted on 2022-10-11
2780 FBXL4 deficiency promotes mitophagy by elevating NIX.
Elcocks, H.; Brazel, A. J.; McCarron, K. R.; Kaulich, M.; Husnjak, K.; Mortiboys, H. J.; Clague, M. J.; Urbe, S.
10.1101/2022.10.11.511735 — cell biology — Posted on 2022-10-11
2782 Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility
Sayaman, R. W.; Miyano, M.; Senapati, P.; Zirbes, A.; Shalabi, S.; Todhunter, M. E.; Seewaldt, V.; Neuhausen, S. L.; Stampfer, M. R.; Schones, D. E.; LaBarge, M. A.
10.1101/2022.09.22.509091 — cancer biology — Posted on 2022-10-11
2783 MS2Prop: A machine learning model that directly predicts chemical properties from mass spectrometry data for novel compounds
Voronov, G.; Frandsen, A.; Bargh, B.; Healey, D.; Lightheart, R.; Kind, T.; Dorrestein, P. C.; Colluru, V.; Butler, T.
10.1101/2022.10.09.511482 — bioinformatics — Posted on 2022-10-11
2785 Redefining normal breast cell populations using long noncoding RNAs
Bitar, M.; Rivera, I. S.; Pimentel de Almeida, I.; Shi, W.; Ferguson, K.; Beesley, J.; Lakhani, S.; Edwards, S.; French, J. D.
10.1101/2022.09.06.506112 — cell biology — Posted on 2022-10-11
2786 Reduced Cdc14 phosphatase activity impairs septation, hyphal differentiation and pathogenesis and causes echinocandin hypersensitivity in Candida albicans
Milholland, K. L.; AbdelKhalek, A.; Baker, K. M.; Hoda, S.; DeMarco, A. G.; Naughton, N. H.; Koeberlein, A. N.; Lorenz, G. R.; Anandasothy, K.; Esperilla-Munoz, A.; Narayanan, S. K.; Correa-Bordes, J.; Briggs, S. D.; Hall, M. C.
10.1101/2022.09.29.510203 — molecular biology — Posted on 2022-10-11
2787 Co-immunization with pre-erythrocytic antigens alongside circumsporozoite protein can enhance sterile protection against Plasmodium sporozoite infection.
Vigdorovich, V.; Patel, H.; Watson, A.; Raappana, A.; Reynolds, L.; Selman, W.; Beeman, S.; Edlefsen, P. T.; Kappe, S. H. I.; Sather, D. N.
10.1101/2022.06.17.496580 — immunology — Posted on 2022-10-11
2790 Distinct roles for canonical and variant histone H3 lysine 36 in Polycomb silencing
Salzler, H. R.; Vandadi, V.; McMichael, B. D.; Brown, J. C.; Boerma, S. A.; Leatham-Jensen, M. P.; Adams, K. M.; Meers, M. P.; Simon, J. M.; Duronio, R. J.; McKay, D. J.; Matera, A. G.
10.1101/2022.10.11.511749 — genomics — Posted on 2022-10-11
2792 Phylogenetic and biogeographical traits predict unrecognized hosts of zoonotic leishmaniasis
Glidden, C. K.; Murran, A.; Silva, R. A.; Castellanos, A. A.; Han, B. A.; Mordecai, E. A.
10.1101/2022.10.11.511693 — ecology — Posted on 2022-10-11
2794 On the causes, consequences, and avoidance of PCR duplicates: towards a theory of library complexity
Rochette, N. C.; Rivera-Colon, A. G.; Walsh, J.; Sanger, T.; Campbell-Staton, S. C.; Catchen, J. M.
10.1101/2022.10.10.511638 — molecular biology — Posted on 2022-10-11
2795 Host and Water Microbiota are Differentially Linked to Potential Human Pathogen Accumulation in Oysters
Diner, R. E.; Zimmer-Faust, A.; Cooksey, E.; Allard, S.; Kodera, S. M.; Kunselman, E.; Garodia, Y.; Allen, A. E.; Griffith, J.; Gilbert, J. A.
10.1101/2022.10.11.511793 — microbiology — Posted on 2022-10-11
2796 Functional screens of barcoded expression libraries uncover new gene functions in carbon utilization among gut Bactereroidales
Huang, Y. Y.; Price, M. N.; Hung, A.; Gal-Oz, O.; Ho, D.; Carion, H.; Deutschbauer, A. M.; Arkin, A. P.
10.1101/2022.10.10.511384 — microbiology — Posted on 2022-10-11
2797 Breadth of Fc-mediated effector function delineates grades of clinical immunity following human malaria challenge
Nkumama, I. N.; Odera, D.; Musasia, F.; Mwai, K.; Nyamako, L.; Murungi, L.; Tuju, J.; Furle, K.; Rosenkranz, M.; Kimathi, R.; Njuguna, P.; Hamaluba, M.; Kapulu, M. C.; Frank, R.; CHMI-SIKA Study Team, ; Osier, F.
10.1101/2022.10.11.511755 — immunology — Posted on 2022-10-11
2798 An optimized messenger RNA vaccine candidate protects non-human primates from Zika virus infection
Bollman, B. A.; Nunna, N.; Bahl, K.; Hsiao, C. J.; Bennett, H.; Butler, S.; Foreman, B.; Burgomaster, K. E.; Aleshnick, M.; Kong, W.-P.; Fisher, B. E.; Ruckward, T. J.; Morabito, K. M.; Graham, B. S.; Dowd, K. A.; Pierson, T.; Carfi, A.
10.1101/2022.10.11.511814 — immunology — Posted on 2022-10-11
2801 Genome-wide RNA binding analysis of C9orf72 poly(PR) dipeptides
Balendra, R.; Ruiz de los Mozos, I.; Glaria, I.; Milioto, C.; Odeh, H. M.; Wilson, K. M.; Ule, A. M.; Hallegger, M.; Masino, L.; Martin, S.; Patani, R.; Shorter, J.; Ule, J.; Isaacs, A.
10.1101/2022.10.10.511318 — neuroscience — Posted on 2022-10-11
2805 Designed active-site library reveals thousands of functional GFP variants
Weinstein, J. Y.; Aldaravi, C. M. G.; Lipsh-Sokolik, R.; Hoch, S. Y.; Liebermann, D.; Nevo, R.; Weissman, H.; Petrovich-Kopitman, E.; Margulies, D.; Ivankov, D.; McCandlish, D.; Fleishman, S. J.
10.1101/2022.10.11.511732 — biochemistry — Posted on 2022-10-11
2807 A CREBZF/Zhangfei isoform activates CHOP during prolonged cellular stress
Li, Y.; Yip, W. K.; Penney, J.; Taylor, T.; Zhang, Y.; Zeng, M.; Audas, T. E.; Lu, R.
10.1101/2022.10.10.511668 — molecular biology — Posted on 2022-10-11
2812 Bacillus velezensis SQR9 sways the rhizosphere community and its sociality toward cooperation and plant growth promotion
Liu, Y.; Xu, Z.; Xun, W.; Stefanic, P.; Yang, T.; Miao, Y.; Zhang, N.; Zhang, R.; Shen, Q.; Mulec, I. M.
10.1101/2022.10.11.511700 — microbiology — Posted on 2022-10-11
2813 Characterizing biofilm interactions between Ralstonia insidiosa and Chryseobacterium gleum
Foote, A.; Schutz, K.; Zhao, Z.; DiGianivittorio, P.; Korwin-Mihavics, B. R.; LiPuma, J. J.; Wargo, M. J.
10.1101/2022.10.11.511742 — microbiology — Posted on 2022-10-11
2815 Strain and serovar variants of Salmonella enterica exhibit diverse tolerance to food chain-related stress
Pye, H. V.; Thilliez, G.; Acton, L.; Kolenda, R.; Al-Khanaq, H.; Grove, S.; Kingsley, R. A.
10.1101/2022.10.11.511718 — microbiology — Posted on 2022-10-11
2817 Disturbed trophoblast transition links preeclampsia progression from placenta to the maternal syndrome
Nonn, O.; Debnath, O.; Valdes, D. S.; Sallinger, K.; Secener, A. K.; Haider, S.; Fischer, C.; Tiesmeyer, S.; Nimo, J.; Kuenzer, T.; Maxian, T.; Knoefler, M.; Karau, P.; Bartolomaeus, H.; Kroneis, T.; Frolova, A.; Neuper, L.; Haase, N.; Kraeker, K.; Kedziora, S.; Forstner, D.; Verlohren, S.; Stern, C.; Coscia, F.; Sugulle, M.; Jones, S.; Thilaganathan, B.; Eils, R.; Huppertz, B.; El-Heliebi, A.; Staff, A. C.; Mueller, D. N.; Dechend, R.; Gauster, M.; Ishaque, N.; Herse, F.
10.1101/2022.10.10.511539 — systems biology — Posted on 2022-10-11
2818 The SARS-CoV-2 envelope (E) protein forms a calcium- and voltage-activated calcium channel
Antonides, L. H.; Hurst, Q. W.; Ives, C. M.; Ramberg, K.; Ostrovitas, N.; Scanlan, E.; Caffrey, M.; Pitt, S. J.; Zachariae, U.
10.1101/2022.10.11.511775 — biophysics — Posted on 2022-10-11
2819 Lis1 relieves cytoplasmic dynein-1 auto-inhibition by acting as a molecular wedge
Karasmanis, E. P.; Reimer, J. M.; Kendrick, A. A.; Rodriguez, J. A.; Truong, J. B.; Lahiri, I.; Reck-Peterson, S. L.; Leschziner, A. E.
10.1101/2022.10.10.511666 — cell biology — Posted on 2022-10-11
2823 Natural rubber reduces herbivory and alters the microbiome below ground
Boettner, L.; Malacrino, A.; Schulze Gronover, C.; van Deenen, N.; Mueller, B.; Xu, S.; Gershenzon, J.; Pruefer, D.; Huber, M.
10.1101/2022.10.10.511194 — plant biology — Posted on 2022-10-11
2830 Pytometry: Flow and mass cytometry analytics in Python
Buttner, M.; Hempel, F.; Ryborz, T.; Theis, F.; Schultze, J. L.
10.1101/2022.10.10.511546 — systems biology — Posted on 2022-10-11
2832 Inhibition of integrin alpha V (CD51) reduces inflammation and transition to heart failure following pressure overload
Delacroix, C.; Achab-Ali, A.; Alayrac, P.; Gandon-Renard, M.; Drame, F.; Sassoon, D. A.; Silvestre, J.-S.; Hulot, J.-S.
10.1101/2022.10.10.511547 — pharmacology and toxicology — Posted on 2022-10-11
2833 Structural surfaceomics reveals an AML-specific conformation of Integrin-β2 as a CAR-T therapy target
Mandal, K.; Wicaksono, G.; Yu, C.; Adams, J. J.; Hoopmann, M. R.; Temple, W. C.; Escobar, B. P.; Gorelik, M.; Ihling, C. H.; Nix, M. A.; Naik, A.; Ramos, E.; Kasap, C.; Steri, V.; Serrano, J. A. C.; Salangsang, F.; Phojanakong, P.; McMillan, M.; Gavallos, V.; Leavitt, A. D.; Sinz, A.; Huang, B. J.; Stieglitz, E.; Smith, C. C.; Moritz, R. L.; Sidhu, S. S.; Huang, L.; Wiita, A. P.
10.1101/2022.10.10.511511 — cancer biology — Posted on 2022-10-11
2834 Mechanism of dual pharmacological correction and potentiation of human CFTR
Wang, C.; Yang, Z.; Loughlin, B. J.; Xu, H.; Veit, G.; Vorobiev, S.; Clarke, O. B.; Jiang, F.; Li, Y.; Singh, S.; Rich, Z.; Menten, E. R.; Grassucci, R. A.; Wang, W.; Mezzell, A.; Fu, Z.; Wong, K.-H.; Wang, J.; Wetmore, D. R.; Sutton, R. B.; Brouillette, C. G.; Urbatsch, I. L.; Kappes, J. C.; Lukacs, G. L.; Frank, J.; Hunt, J. F.
10.1101/2022.10.10.510913 — biophysics — Posted on 2022-10-11
2836 Depletion Assisted Hemin Affinity (DAsHA) Proteomics Reveals an Expanded Landscape of Heme Binding Proteins
Kim, H.; Moore, C. M.; Mestre-Fos, S.; Hanna, D. A.; Williams, L. D.; Reddi, A.; Torres, M. P.
10.1101/2022.10.11.511733 — biochemistry — Posted on 2022-10-11
2840 Disentangling the diet composition of chicks of Arctic shorebirds provides a new perspective on trophic mismatches
Zhemchuzhnikov, M. K.; Zhemchuzhnikova, E. A.; Lameris, T. K.; van Bleijswijk, J.; ten Horn, J.; Soloviev, M.; Golovnyuk, V.; Sukhova, M.; Popovkina, A.; Kutcherov, D.; van Gils, J. A.
10.1101/2022.10.10.511540 — ecology — Posted on 2022-10-11
2842 Characterization of the HHV-6 U20 immunoevasin
Schneider, C. L.; Whyte, M. L.; Konrad, S. L.; Hudson, A. W.
10.1101/2022.10.10.511687 — cell biology — Posted on 2022-10-11
2843 DNA looping mediates cooperative transcription activation
Han, S.; Jiang, Y.; You, L.; Shen, L.; Yang, F.; Cui, N.; Kong, W.; Sun, H.; Zhou, K.; Meng, H.; Chen, Z.; Chen, Y.; Zhang, Y.; Zhou, C.-Z.
10.1101/2022.10.10.511513 — molecular biology — Posted on 2022-10-11
2844 Neural dynamics and geometry for transitive inference
Kay, K.; Wei, X.-X.; Khajeh, R.; Beiran, M.; Cueva, C. J.; Jensen, G.; Ferrera, V. P.; Abbott, L. F.
10.1101/2022.10.10.511448 — neuroscience — Posted on 2022-10-11
2846 Cell type catalog of middle turbinate epithelium
Mathews, F.; Tung, V. S. K.; Foronjy, R.; Boruk, M.; Knowles, J.; Evgrafov, O. V.
10.1101/2022.10.09.511503 — genomics — Posted on 2022-10-11
2847 Influences of rare protein-coding genetic variants on the human plasma proteome in 50,829 UK Biobank participants
Dhindsa, R. S.; Burren, O. S.; Sun, B. B.; Prins, B. P.; Matelska, D.; Wheeler, E.; Mitchell, J.; Oerton, E.; Hristova, V. A.; Smith, K. R.; Carss, K.; Wasilewski, S.; Harper, A. R.; Paul, D. S.; Fabre, M. A.; Runz, H.; Viollet, C.; Challis, B.; Platt, A.; AstraZeneca Genomics Initiative, ; Vitsios, D.; Ashley, E. A.; Whelan, C. D.; Pangalos, M. N.; Wang, Q.; Petrovski, S.
10.1101/2022.10.09.511476 — genomics — Posted on 2022-10-11
2849 The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.
Nelson, C. B.; Rogers, S.; Roychoudhury, K.; Tan, Y. S.; Atkinson, C. J.; Sobinoff, A. P.; Tomlinson, C. G.; Hsu, A.; Lu, R.; Dray, E.; Haber, M.; Fletcher, J. I.; Cesare, A. J.; Hegde, R. S.; Pickett, H. A.
10.1101/2022.10.10.511510 — cell biology — Posted on 2022-10-11
2851 Exploration of single-cell transcriptomic landscape identifies aberrant glomerular crosstalk in a murine model of WT1 kidney disease
Chandler, J. C.; Jafree, D. J.; Mailk, S.; Pomeranz, G.; Ball, M.; Kolatsi-Joannou, M.; Piapi, A.; Mason, W. J.; Woolf, A. S.; Winyard, P. J.; Mason, A. S.; Waters, A. M.; Long, D. A.
10.1101/2022.10.11.511555 — cell biology — Posted on 2022-10-11
2854 PCLAF-DREAM Drives Alveolar Cell Plasticity for Lung Regeneration
Kim, B.; Huang, Y.; Ko, K.-P.; Zhang, S.; Zou, G.; Zhang, J.; Kim, M.; Little, D.; Ellis, L. V.; Paschini, M.; Jun, S.; Park, K.-S.; Chen, J.; Kim, C.; Park, J.-I.
10.1101/2022.10.11.511761 — cell biology — Posted on 2022-10-11
2855 Smooth Muscle Myosin 2 Filaments Dynamically Assemble and Stabilize During Induced Contractility
Bennett, M. A.; Demeulenaere, S. G.; Wu, H.; Patel, H.; Sala, S.; Longtine, E. R.; Oakes, P. W.; Beach, J. R.
10.1101/2022.10.10.511341 — cell biology — Posted on 2022-10-11
2856 A role for caveolar proteins in regulation of the circadian clock
Fonseka, S.; Weger, B. D.; Weger, M.; Martel, N.; Hall, T. E.; Varasteh Moradi, S.; Gabriel, C. H.; Kramer, A.; Ferguson, C.; Fernandez-Rojo, M. A.; Alexandrov, K.; Rawashdeh, O.; McMahon, K.-A.; Gachon, F.; Parton, R. G.
10.1101/2022.10.10.511681 — cell biology — Posted on 2022-10-11
2858 A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection
Heisler, D. B.; Johnson, K. A.; Ohlson, M. B.; Ma, D. H.; Zhang, L.; Tran, M.; Corley, C. D.; Abrams, M. E.; McDonald, J. G.; Schoggins, J. W.; Alto, N. M.; Radhakrishnan, A.
10.1101/2022.10.10.510128 — cell biology — Posted on 2022-10-11
2859 Ritualistic use of ayahuasca enhances a shared functional connectome identity with others.
Mallaroni, P.; Mason, N. L.; Kloft, L.; Reckweg, J. T.; van Oorsouw, K.; Toennes, S. W.; Tolle, H. M.; Amico, E.; Ramaekers, J. G.
10.1101/2022.10.07.511268 — neuroscience — Posted on 2022-10-11
2862 Network-based hub biomarker discovery for glaucoma
Zhang, X.; Ma, S.; Shang, X.; Zhang, X.; Kong, L.; Jason, H.; Huang, Y.; Zhu, Z.; Liu, S.; Kiburg, K.; Shi, D.; Wang, Y.; Bao, Y.; Lai, H.; Wang, W.; Hu, Y.; Zhao, K.; Hu, G.; Liang, H.; Yu, H.; Zhang, L.; He, M.
10.1101/2022.10.09.511456 — bioinformatics — Posted on 2022-10-11
2866 Innate immune sensing of self-derived double-stranded RNA by RIG-I-MAVS-TNF-α regulates the survival and senescence fate of SARS-2-S syncytia
Wan, L.; Li, H.; Huang, L.; Liu, M.; Li, J.; Yang, Y.; Zhao, R.; Liu, J.; Yang, X.; Ma, E.; Sun, L.; Hou, X.; Zhang, X.; Zhang, Y.; Yan, Q.; Liu, J.; Li, X.; Cheng, G.; Gao, Q.; Xu, J.; Hou, L.; Wei, C.; Zhong, H.
10.1101/2022.10.10.511541 — cell biology — Posted on 2022-10-11
2867 MIGH-T: A Multi-Parametric and High-Throughput Platform for Host-Virus Binding Screens
Schlegel, J.; Porebski, B.; Andronico, L.; Hanke, L.; Edwards, S.; Brismar, H.; Murrell, B.; McInerney, G. M.; Fernandez-Capetillo, O.; Sezgin, E.
10.1101/2022.10.10.511545 — synthetic biology — Posted on 2022-10-11
2869 Genomic tracking of SARS-COV-2 variants in Myanmar
Oo, K. Z.; Htun, Z. W.; Aung, N. M.; Win, K. K.; Htoo, S. P.; Oo, T. W.; Linn, K. Z.; Aung, P. K.; Zaw, M. T.; Tun, K. M.; Myint, K.; Lwin, K. K.
10.1101/2022.10.10.511623 — bioinformatics — Posted on 2022-10-11
2870 GenSLMs: Genome-scale language models reveal SARS-CoV-2 evolutionary dynamics.
Zvyagin, M. T.; Brace, A.; Hippe, K.; Deng, Y.; Zhang, B.; Orozco Bohorquez, C.; Clyde, A.; Kale, B.; Perez-Rivera, D.; Ma, H.; Mann, C. M.; Irvin, M.; Pauloski, J. G.; Ward, L.; Hayot, V.; Emani, M.; Foreman, S.; Xie, Z.; Lin, D.; Shukla, M.; Nie, W.; Romero, J.; Dallago, C.; Vahdat, A.; Xiao, C.; Gibbs, T.; Foster, I.; Davis, J. J.; Papka, M. E.; Brettin, T.; Anandkumar, A.; Vishwanath, V.; Ramanathan, A.
10.1101/2022.10.10.511571 — bioinformatics — Posted on 2022-10-11
2871 SAGA histone acetyltransferase module facilitates chromatin accessibility to SMC5/6
Mahrik, L.; Stefanovie, B.; Maresova, A.; Princova, J.; Kolesar, P.; Lelkes, E.; Helmlinger, D.; Prevorovsky, M.; Palecek, J. J.
10.1101/2022.09.24.508842 — genetics — Posted on 2022-10-11
2872 Associative memory retrieval resolves anticipated uncertainty of upcoming perceptual decisions.
Bornstein, A. M.; Aly, M.; Feng, S. F.; Turk-Browne, N. B.; Norman, K. A.; Cohen, J. D.
10.1101/186817 — neuroscience — Posted on 2022-10-11
2875 A systematic genotype-phenotype map for missense variants in the human intellectual disability-associated gene GDI1
Silverstein, R. A.; Sun, S. A.; Verby, M.; Weile, J.; Wu, Y.; Gebbia, M.; Fotiadou, I.; Kitaygorodsky, J.; Roth, F. P.
10.1101/2021.10.06.463360 — genetics — Posted on 2022-10-11
2882 The formation and closure of macropinocytic cups in a model system
Lutton, J.; Coker, H.; Paschke, P.; Munn, C.; King, J. S.; Kay, R.; Bretschneider, T.
10.1101/2022.10.07.511330 — cell biology — Posted on 2022-10-11
2883 Cilium proteomics reveals Numb as a positive regulator of the Hedgehog signaling pathway
Liu, X.; Yam, P.; Chen, W.-J.; Schlienger, S.; Torres Gutierrez, O.; Cai, E.; Zhang, J.; Ting, A. Y.; Branon, T. C.; Cayouette, M.; Charron, F.; Ge, X.
10.1101/2022.10.10.511655 — cell biology — Posted on 2022-10-11
2885 Multiscale model of the different modes of cancer cell invasion
Ruscone, M.; Montagud, A.; Chavrier, P.; Destaing, O.; Zinovyev, A.; Barillot, E.; Noel, V.; Calzone, L.
10.1101/2022.10.07.511296 — bioinformatics — Posted on 2022-10-11
2886 A novel intranasal administration adenoviral vector-based platform for rapid COVID-19 vaccine development
Yuan, Y.; Gao, X.; Ni, F.; Xie, W.; Fu, W.; Zhang, G.; Hu, H.; Li, Y.; Hu, Q.; Huang, C.; Liu, B.; Liu, Y.; Shen, Q.; Liang, M.
10.1101/2022.02.21.481247 — immunology — Posted on 2022-10-11
2887 Photosystem II monomeric antenna CP26 has a key role in Non-Photochemical Quenching in Chlamydomonas reinhardtii
Cazzaniga, S.; Kim, M.; Pivato, M.; Perozeni, F.; Sardar, S.; D'Andrea, C.; Jin, E.; Ballottari, M.
10.1101/2022.09.01.506249 — plant biology — Posted on 2022-10-11
2889 Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility
Sayaman, R. W.; Miyano, M.; Senapati, P.; Zirbes, A.; Shalabi, S.; Todhunter, M. E.; Seewaldt, V.; Neuhausen, S. L.; Stampfer, M. R.; Schones, D. E.; LaBarge, M. A.
10.1101/2022.09.22.509091 — cancer biology — Posted on 2022-10-11
2892 A suberized exodermis is required for tomato drought tolerance
Canto-Pastor, A.; Kajala, K.; Shaar-Moshe, L.; Manzano, C.; Timilsena, P.; De Bellis, D.; Gray, S.; Holbein, J.; Yang, H.; Mohammad, S.; Nirmal, N.; Suresh, K.; Ursache, R.; Mason, G. A.; Gouran, M.; West, D. A.; Borowsky, A. T.; Shackel, K. A.; Sinha, N.; Bailey-Serres, J.; Geldner, N.; Li, S.; Franke, R. B.; Brady, S. M.
10.1101/2022.10.10.511665 — plant biology — Posted on 2022-10-11
2895 Critical pollination chemistry: Specific sesquiterpene floral volatiles in carrot inhibit honey bee feeding.
Quarrell, S. R.; Weinstein, A. M.; Hannah, L.; Bonavia, N.; del Borrello, O.; Flematti, G. R.; Bohman, B.
10.1101/2022.10.11.511710 — plant biology — Posted on 2022-10-11
2897 Allelic compatibility in plant immune receptors facilitates engineering of new effector recognition specificities.
Bentham, A. R.; De la Concepcion, J. C.; Benjumea, J. V.; Jones, S.; Mendel, M.; Stubbs, J.; Stevenson, C. E.; Maidment, J. H.; Kourelis, J.; Zdrzalek, R.; Kamoun, S.; Banfield, M. J.
10.1101/2022.10.10.511592 — plant biology — Posted on 2022-10-11
2899 The TUDOR domain of SMN is an H3K79me1 histone mark reader
Binda, O.; Kimenyi Ishimwe, A. B.; Galloy, M.; Jacquet, K.; Corpet, A.; Fradet-Turcotte, A.; Cote, J.; Lomonte, P.
10.1101/2022.10.06.511070 — biochemistry — Posted on 2022-10-11
2900 SPOP targets the immune transcription factor IRF1 for proteasomal degradation
Vunjak, M.; Schwartz, I.; Cantoran-Garcia, A.; Mastrovito, M.; Hinterndorfer, M.; de Almeida, M.; Budroni, V.; Wang, J.; Froussios, K.; Jude, J.; Decker, T.; Zuber, J.; Versteeg, G. A.
10.1101/2022.10.10.511567 — cell biology — Posted on 2022-10-11
2901 Adult neural stem cells and neurogenesis are resilient to intermittent fasting
Gabarro-Solanas, R.; Davaatseren, A.; Kepcija, T.; Crespo-Enriquez, I.; Urban, N.
10.1101/2022.07.08.499318 — neuroscience — Posted on 2022-10-11
2902 Preparing future STEM faculty nationwide through flexible teaching professional development
Goldberg, B.; Bruff, D.; Greenler, R.; Barnicle, K.; Green, N.; Campbell, L.; Laursen, S.; Ford, M.; Serafini, A.; Mack, C.; Carley, T.; Maimone, C.; Campa, H.
10.1101/2022.10.06.511090 — scientific communication and education — Posted on 2022-10-11
2907 kimma: flexible linear mixed effects modeling with kinship for RNA-seq data
Dill-McFarland, K. A.; Mitchell, K.; Batchu, S.; Segnitz, R. M.; Benson, B.; Janczyk, T.; Cox, M. S.; Mayanja-Kizza, H. A.; Boom, W. H.; Benchek, P.; Stein, C.; Hawn, T. R.; Altman, M. C.
10.1101/2022.10.10.508946 — bioinformatics — Posted on 2022-10-11
2908 Publicly Available Privacy-preserving Benchmarks for Polygenic Prediction
Witteveen, M. J.; Pedersen, E. M.; Meijsen, J.; Andersen, M. R.; Prive, F.; Speed, D.; Vilhjalmsson, B. J.
10.1101/2022.10.10.510645 — genetics — Posted on 2022-10-11
2909 Variation in the rate lateral gene transfers accumulate in a grass lineage
Raimondeau, P.; Bianconi, M. E.; Pereira, L.; Parisod, C.; Christin, P.-A.; Dunning, L. T.
10.1101/2022.10.10.511554 — evolutionary biology — Posted on 2022-10-11
2911 kimma: flexible linear mixed effects modeling with kinship for RNA-seq data
Dill-McFarland, K. A.; Mitchell, K.; Batchu, S.; Segnitz, R. M.; Benson, B.; Janczyk, T.; Cox, M. S.; Mayanja-Kizza, H. A.; Boom, W. H.; Benchek, P.; Stein, C.; Hawn, T. R.; Altman, M. C.
10.1101/2022.10.10.508946 — bioinformatics — Posted on 2022-10-11
2913 Cilium proteomics reveals Numb as a positive regulator of the Hedgehog signaling pathway
Liu, X.; Pam, P.; Chen, W.-J.; Schlienger, S.; Torres Gutierrez, O.; Cai, E.; Zhang, J.; Ting, A. Y.; Branon, T. C.; Cayouette, M.; Charron, F.; Ge, X.
10.1101/2022.10.10.511655 — cell biology — Posted on 2022-10-11
2919 The glutathione S-transferase Gstt1 is a robust driver of survival and dissemination in metastases
Ferrer, C. M.; Boon, R.; Cho, H.; Bernasocchi, T.; Wong, L. P.; Cetinbas, M.; Haggerty, E. R.; Mitsiades, I.; Wojtkiewicz, G. R.; McLoughlin, D. E.; Kugel, S.; Rheinbay, E.; Sadreyev, R.; Juric, D.; Mostoslavsky, R.
10.1101/2022.09.10.507413 — cancer biology — Posted on 2022-10-10
2920 A genome-wide mutational constraint map quantified from variation in 76,156 human genomes
Chen, S.; Francioli, L.; Goodrich, J.; Collins, R.; Kanai, M.; Wang, Q.; Alfoldi, J.; Watts, N.; Vittal, C.; Gauthier, L.; Poterba, T.; Wilson, M.; Tarasova, Y.; Phu, W.; Yohannes, M.; Koenig, Z.; Farjoun, Y.; Banks, E.; Donnelly, S.; Gabriel, S.; Gupta, N.; Ferriera, S.; Tolonen, C.; Novod, S.; Bergelson, L.; Roazen, D.; Ruano-Rubio, V.; Covarrubias, M.; Llanwarne, C.; Petrillo, N.; Wade, G.; Jeandet, T.; Munshi, R.; Tibbetts, K.; gnomAD Project Consortium, ; O'Donnell-Luria, A.; Solomonson, M.; Seed, C.; Martin, A.; Talkowski, M.; Rehm, H.; Daly, M.; Tiao, G.; Neale, B.; MacArthur, D.; Karc
10.1101/2022.03.20.485034 — genetics — Posted on 2022-10-10
2921 Complex hybridization between deeply diverged fish species in a disturbed ecosystem
Banerjee, S. M.; Powell, D. L.; Moran, B. M.; Ramirez-Duarte, W. F.; Langdon, Q. K.; Gunn, T. R.; Vazquez, G.; Rochman, C.; Schumer, M.
10.1101/2022.10.08.511445 — evolutionary biology — Posted on 2022-10-10
2925 Phosphoprotein Phosphatase Activity Positively Regulates Oligomeric Pyrin to Trigger Inflammasome Assembly in Phagocytes
Malek, H. S.; Magnotti, F.; Loeven, N. A.; Delgado, J. M.; Kettenbach, A. N.; Henry, T.; Bliska, J. B.
10.1101/2022.03.23.485108 — immunology — Posted on 2022-10-10
2928 Training-Induced Circuit-Specific Excitatory Synaptogenesis is Required for Effort Control
Severino, F. P. U.; Lawal, O.; Sakers, K.; Wang, S.; Kim, N.; Friedman, A.; Johnson, S.; Sriworarat, C.; Hughes, R.; Soderling, S. H.; Kim, I. H.; Yin, H.; Eroglu, C.
10.1101/2021.04.20.440613 — neuroscience — Posted on 2022-10-10
2929 PanIN and CAF Transitions in Pancreatic Carcinogenesis Revealed with Spatial Data Integration
Bell, A. T. F.; Mitchell, J. T.; Kiemen, A. L.; Fujikura, K.; Fedor, H.; Gambichler, B.; Deshpande, A.; Wu, P.-H.; Sidiropoulos, D. N.; Erbe, R.; Stern, J.; Chan, R.; Williams, S.; Chell, J. M.; Zimmerman, J. W.; Wirtz, D.; Jaffee, E. M.; Wood, L. D.; Fertig, E. J.; Kagohara, L. T.
10.1101/2022.07.16.500312 — cancer biology — Posted on 2022-10-10
2931 Inflammatory Signaling in Pancreatic Cancer Transfers Between a Single-cell RNA Sequencing Atlas and Co-Culture
Kinny-Koster, B.; Guinn, S.; Tandurella, J. A.; Mitchell, J. T.; Sidiropoulos, D. N.; Loth, M.; Lyman, M. R.; Pucsek, A. B.; Seppala, T. T.; Cherry, C.; Suri, R.; Zlomke, H.; He, J.; Wolfgang, C. L.; Yu, J.; Zheng, L.; Ryan, D. P.; Ting, D. T.; Kimmelman, A.; Gupta, A.; Danilova, L.; Elisseef, J.; Wood, L. D.; Stein-O'Brien, G.; Kagohara, L. T.; Jaffee, E. M.; Burkhart, R. A.; Fertig, E. J.; Zimmerman, J. W.
10.1101/2022.07.14.500096 — cancer biology — Posted on 2022-10-10
2937 Structural snapshots uncover a lock-and-key type conserved activation mechanism of β-arrestins by GPCRs
Maharana, J.; Sarma, P.; Yadav, M. K.; Saha, S.; Singh, V.; Saha, S.; Chami, M.; Banerjee, R.; SHUKLA, A. K.
10.1101/2022.10.10.511556 — biochemistry — Posted on 2022-10-10
2938 TRB3 augments IL1β-TLR4 signaling by engaging Flightless-homolog 1.
Gonuguntla, S.; Humphrey, R. K.; Gorantla, A.; Hao, E.; Jhala, U. S.
10.1101/2022.10.09.511391 — biochemistry — Posted on 2022-10-10
2939 Mining the human gut microbiome identifies mycobacterial D-arabinan degrading enzymes
Al-Jourani, O.; Benedict, S. T.; Ross, J.; Layton, A. J.; van der Peet, P.; Marando, V.; Bailey, N. P.; Heunis, T.; Manion, J.; Mensitieri, F.; Franklin, A.; Abellon-Ruiz, J.; Oram, S. L.; Parsons, L.; Cartmell, A.; Wright, G. S.; Basle, A.; Trost, M.; Henrissat, B.; Munoz-Munoz, J.; Hirt, R. P.; Keissling, L. L.; Lovering, A. L.; Williams, S. J.; Lowe, E. C.; Moynihan, P. J.
10.1101/2022.07.22.500997 — biochemistry — Posted on 2022-10-10
2940 Structural Genomics of the Human Dopamine Receptor System
Xu, P.; Huang, S.; Krumm, B. E.; Zhuang, Y.; Mao, C.; Zhang, Y.; Wang, Y.; Huang, X.-P.; Liu, Y.-F.; He, X.; Li, H.; Yin, W.; Jiang, Y.; Zhang, Y.; Roth, B. L.; Xu, H. E.
10.1101/2022.10.09.511478 — biochemistry — Posted on 2022-10-10
2944 Gαs slow conformational transition upon GTP binding and a novel Gαs regulator
Ahn, D.; Provasi, D.; Duc, N. M.; Xu, J.; Salas-Estrada, L.; Spasic, A.; Yun, M. W.; Kang, J.; Gim, D.; Lee, J.; Filizola, M.; Chung, K. Y.
10.1101/2022.10.10.511514 — molecular biology — Posted on 2022-10-10
2945 Absence of estrogen leads to defects in spermatogenesis and increased semen abnormalities in male rabbits
Dewaele, A.; Dujardin, E.; Andre, M.; Albina, A.; Jammes, H.; Giton, F.; Sellem, E.; Jolivet, G.; Pailhoux, E.; Pannetier, M.
10.1101/2022.10.10.511525 — molecular biology — Posted on 2022-10-10
2947 E3-specific degrader discovery by dynamic tracing of substrate receptor abundance
Hanzl, A.; Barone, E.; Bauer, S.; Yue, H.; Nowak, R. P.; Hahn, E.; Pankevich, E. V.; Koren, A.; Kubicek, S.; Fischer, E. S.; Winter, G. E.
10.1101/2022.10.10.511612 — molecular biology — Posted on 2022-10-10
2951 SBT-272 improves TDP-43 pathology in the ALS motor cortex by modulating mitochondrial integrity, motility, and function
Gautam, M.; Genc, B.; Helmold, B.; Ahrens, A.; Kuka, J.; Makrecka-Kuka, M.; Gunay, A.; Kocak, N.; Aguilar-Wickings, I. R.; Keefe, D.; Zheng, G.; Swaminathan, S.; Redmon, M.; Zariwala, H. A.; Ozdinler, P. H.
10.1101/2022.10.04.510854 — neuroscience — Posted on 2022-10-10
2953 Brief report: Reclassifying SCLC-Y as SMARCA4 deficient malignancies - resolving the controversy
Ng, J.; Cai, L.; Girard, L.; Prall, O.; Rajan, N.; Khoo, C.; Batrouney, A.; Kersbergen, A.; Christie, M.; Minna, J.; Burr, M. L.; Sutherland, K. D.
10.1101/2022.10.09.511505 — cancer biology — Posted on 2022-10-10
2954 Paclitaxel-loaded Cationic Fluid Lipid Nanodiscs and Liposomes with Brush-Conformation PEG Chains Penetrate Breast Tumors and Trigger Caspase-3 Activation
Simon-Gracia, L.; Scodeller, P. D.; Fisher, W. S.; Sidorenko, V.; Steffes, V. M.; Ewert, K. K.; Safinya, C. R.; Teesalu, T.
10.1101/2022.03.28.486128 — biophysics — Posted on 2022-10-10
2956 Energy extraction from air: structural basis of atmospheric hydrogen oxidation
Grinter, R.; Kropp, A.; Venugopal, H.; Senger, M.; Badley, J.; Cabotaje, P.; Stripp, S. T.; Barlow, C.; Belousoff, M. J.; Cook, G. M.; Vincent, K.; Schittenhelm, R. B.; Khalid, S.; Berggren, G.; Greening, C.
10.1101/2022.10.09.511488 — biochemistry — Posted on 2022-10-10
2959 Polymorphisms in HIV-1 nef are associated with plasma concentration of biomarkers of endothelial activation
Mezoh, G.; Lutchman, N.; Cave, E. M.; Prigge, K.; Worsley, C.; Martinson, N.; Mayne, E.; Lambson, B. E.; Moore, P.; Crowther, N. J.
10.1101/2022.10.10.511468 — biochemistry — Posted on 2022-10-10
2960 Elucidating the molecular programming of a nonlinear nonribosomal peptide synthetase responsible for fungal siderophore biosynthesis.
Jenner, M.; Hai, Y.; Nguyen, H. H.; Passmore, M.; Skyrud, W.; Kim, J.; Garg, N. K.; Zhang, W.; Ogorzalek Loo, R. R.; Tang, Y.
10.1101/2022.10.10.511241 — biochemistry — Posted on 2022-10-10
2962 Fin whale singalong: evidence of song conformity
Romagosa, M.; Nieukirk, S.; Cascao, I.; Marques, T. A.; Dziak, R.; Royer, J.-Y.; O'Brien, J.; Mellinger, D. K.; Pereira, A.; Ugalde, A.; Papale, E.; Aniceto, S.; Buscaino, G.; Rasmussen, M.; Matias, L.; Prieto, R.; Silva, M. A.
10.1101/2022.10.05.510968 — animal behavior and cognition — Posted on 2022-10-10
2965 Gut microbial disruption in critically ill patients with COVID-19 associated pulmonary aspergillosis
Schult, D.; Maurer, C.; Koyumdzhieva, P.; Reitmeier, S.; Middelhoff, M.; Rasch, S.; List, M.; Janssen, K.-P.; Steiger, K.; Protzer, U.; Schmid, R. M.; Neuhaus, K.; Haller, D.; Quante, M.; Lahmer, T.
10.1101/2022.10.08.511408 — microbiology — Posted on 2022-10-10
2970 Novel genetic traits in Xanthomonas unveiled by the complete genome sequencing of three clade-1 xanthomonads
Peduzzi, C.; Sagia, A.; Burokiene, D.; Katalin Nagy, I.; Fischer-Le Saux, M.; Portier, P.; Dereeper, A.; Cunnac, S.; Roman-Reyna, V.; Jacobs, J. M.; Bragard, C.; Koebnik, R.
10.1101/2022.10.10.511549 — microbiology — Posted on 2022-10-10
2973 TsTX-kappa beta (Ts8), a neurotoxin from the venom of the scorpion Tityus serrulatus: antimicrobial and hemolytic activity.
Oliveira, T. d. J.; Pereira, N.; Riciluca, K. C. T.; do Nascimento, S. M.; Castro de Oliveira, U.; Silva Junior, P. I.
10.1101/2022.10.09.511467 — microbiology — Posted on 2022-10-10
2974 Post-translational modification by the Pgf glycosylation machinery modulates Streptococcus mutans physiology and virulence
de Mojana di Cologna, N.; Andresen, S.; Samaddar, S.; Archer-Hartmann, S. A.; Ganguly, T.; Kajfasz, J. K.; Garcia, B. A.; Saengpet, I.; Peterson, A. M.; Azadi, P.; Szymanski, C. M.; Lemos, J. A.; Abranches, J. A.
10.1101/2022.10.10.511621 — microbiology — Posted on 2022-10-10
2976 PRAMEL7/CUL2 axis regulates NuRD stability to establish ground-state pluripotency in embryonic stem cells
Rupasinghe, M.; Bersaglieri, C.; Pedrioli, D. M. L.; Pedrioli, P. G. A.; Hottiger, M. O.; Cinelli, P.; Santoro, R.
10.1101/2022.10.10.511527 — developmental biology — Posted on 2022-10-10
2980 Structural and biochemical insights into heterotetramer formation between human oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator
Tariq, M.; Ikeya, T.; Togashi, N.; Fairall, L.; Bueno-Alejo, C.; Kamei, S.; Romartinez-Alonso, B.; Muro Campillo, M. A.; Hudson, A. J.; Ito, Y.; Schwabe, J. W.; Dominguez, C.; Tanaka, K.
10.1101/2022.10.10.511529 — biochemistry — Posted on 2022-10-10
2982 Synaptotagmin 7 docks synaptic vesicles for Doc2α-triggered asynchronous neurotransmitter release
Wu, Z.; Kusick, G. F.; Berns, M. M. M.; Raychaudhuri, S.; Itoh, K.; Walter, A. M.; Chapman, E. R.; Watanabe, S.
10.1101/2022.04.21.489101 — neuroscience — Posted on 2022-10-10
2985 Mutation of the ALS/FTD-associated RNA-binding protein FUS alters axonal cytoskeletal organisation
van Tartwijk, F. W.; Wunderlich, L. C. S.; Mela, I.; Makarchuk, S.; Jakobs, M. A. H.; Qamar, S.; Franze, K.; Kaminski Schierle, G. S.; St George-Hyslop, P. H.; Lin, J. Q.; Holt, C. E.; Kaminski, C. F.
10.1101/2022.10.04.510780 — neuroscience — Posted on 2022-10-10
2986 Spatial computing for the control of working memory
Lundqvist, M.; Brincat, S. L.; Rose, J.; Warden, M. R.; Buschman, T. J.; Miller, E. K.; Herman, P.
10.1101/2020.12.30.424833 — neuroscience — Posted on 2022-10-10
2987 PanomiR: A systems biology framework for analysis of multi-pathway targeting by miRNAs
Yeganeh, P. N.; Teo, Y. Y.; Karagkouni, D.; Pita-Juarez, Y.; Morgan, S. L.; Slack, F. J.; Vlachos, I. S.; Hide, W. A.
10.1101/2022.07.12.499819 — systems biology — Posted on 2022-10-10
2990 MS2Prop: A machine learning model that directly predicts chemical properties from mass spectrometry data for novel compounds
Voronov, G.; Frandsen, A.; Bargh, B.; Healey, D.; Lightheart, R.; Kind, T.; Dorrestein, P. C.; Colluru, V.; Butler, T.
10.1101/2022.10.09.511482 — bioinformatics — Posted on 2022-10-10
2992 Natural selection and neutral mutations through the lens of viruses
Chen, J.-M.; Li, G.-H.; Gong, H.-Y.; Sun, M.-H.; Ji, Y.-F.; Chen, R.-X.; Tan, S.-M.; Chen, J.-W.
10.1101/2022.10.10.511542 — evolutionary biology — Posted on 2022-10-10
2993 Scaling patterns of body plans differ among squirrel ecotypes
Linden, T. J.; Burtner, A. E.; Rickman, J.; McFeely, A.; Santana, S. E.; Law, C.
10.1101/2022.10.09.511490 — evolutionary biology — Posted on 2022-10-10
2995 Membrane lipid adaptation of soil Gram-negative bacteria isolates to temperature and pH
Hellequin, E.; Collin, S.; Seder-Colomina, M.; Vequaud, P.; Anquetil, C.; Kish, A.; Huguet, A.
10.1101/2022.10.10.511520 — microbiology — Posted on 2022-10-10
2996 Increased public health threat of avian-origin H3N2 influenza virus during evolution in dogs
Chen, M.; Lyu, Y.; Wu, F.; Zhang, Y.; Li, H.; Wang, R.; Liu, Y.; Yang, X.; Zhou, L.; Zhang, M.; Tong, Q.; Sun, H.; Pu, J.; Liu, J.; Sun, Y.
10.1101/2022.10.10.511550 — microbiology — Posted on 2022-10-10
2999 A first draft genome of Holm oak (Quercus ilex L.), the most representative species of the Mediterranean forest and the Spanish agrosilvopastoral ecosystem dehesa
Rey, M.-D.; Labella-Ortega, M.; Guerrero-Sanchez, V. M.; Carleial, R.; Castillejo, M.-A.; Rodriguez-Franco, A.; Buggs, R.; Ruggieri, V.; Jorrin-Novo, J. V.
10.1101/2022.10.09.511480 — genomics — Posted on 2022-10-10
3000 Epithelial Outgrowth Through Mesenchymal Rings Drives Alveologenesis
Negretti, N. M.; Son, Y.; Crooke, P.; Plosa, E. J.; Benjamin, J. T.; Jetter, C. S.; Bunn, C.; Mignemi, N.; Marini, J.; Hackett, A. N.; Ransom, M.; Nichols, D.; Guttentag, S. H.; Pua, H. H.; Blackwell, T. S.; Zacharias, W.; Frank, D. B.; Kozub, J. A.; Mahadevan-Jansen, A.; Kropski, J. A.; Wright, C. V. E.; Millis, B.; Sucre, J. M. S.
10.1101/2022.10.06.511160 — developmental biology — Posted on 2022-10-10
3001 Intestinal myofibroblasts regulate intestinal epithelial cell plasticity via YAP/TAZ
Pastuła, A.; Janssen, K. P.; Steiger, K.; Slotta-Huspenina, J.; Hauck, S. M.; Schmid, R. M.; Quante, M.; Borgmann, M.; Ruiz-Fernandez, M. J. A.; Wang, T. C.; Friedman, R. A.; Ehmer, U.; Fottner, M.
10.1101/2022.10.07.511327 — cell biology — Posted on 2022-10-10
3003 Drosophila epidermal cells are intrinsically mechanosensitive and drive nociceptive behavioral outputs
Yoshino, J.; Mali, S.; Williams, C.; Morita, T.; Emerson, C.; Arp, C.; Sophie, M.; Yin, C.; The, L.; Chikaya, H.; Motoyoshi, M.; Ishii, K.; Emoto, K.; Bautista, D. M.; Parrish, J. Z.
10.1101/2022.10.07.511265 — neuroscience — Posted on 2022-10-10
3006 Signaling pathways involved in the repression of root nitrate uptake by nitrate in Arabidopsis thaliana
Chaput, V.; Li, J.; Sere, D.; Tillard, P.; Fizames, C.; Moyano, T. C.; Zuo, K.; Martin, A.; Gutierrez, R. A.; Gojon, A.; Lejay, L.
10.1101/2022.10.07.511332 — plant biology — Posted on 2022-10-10
3011 MAMBA: a model-driven, constraint-based multiomic integration method
Ugidos, M.; Nuno-Cabanes, C.; Tarazona, S.; Ferrer, A.; Nielsen, L. K.; Rodriguez-Navarro, S.; Marin de Mas, I.; Conesa, A.
10.1101/2022.10.09.511458 — bioinformatics — Posted on 2022-10-10
3013 Identifying Regulation with Adversarial Surrogate
Teichner, R.; Shomar, A.; Barak, O.; Brenner, N.; Marom, S.; Meir, R.; Eytan, D.
10.1101/2022.10.08.511451 — bioengineering — Posted on 2022-10-10
3014 Escaping antibody responses to bacteriolytic enzymes Pal and Cpl-1 by epitope scanning and engineering
Harhala, M. A.; Gembara, K.; Rybicka, I.; Kazmierczak, Z.; Miernikiewicz, P.; Majewska, J.; Budziar, W.; Nasulewicz-Goldeman, A.; Nelson, D. C.; Owczarek, B.; Dabrowska, K.
10.1101/2022.10.06.511193 — bioengineering — Posted on 2022-10-10
3015 Fin whale singalong: evidence of song conformity
Romagosa, M.; Nieukirk, S.; Cascao, I.; Marques, T. A.; Dziak, R.; Royer, J.-Y.; O'Brien, J.; Mellinger, D. K.; Pereira, A.; Ugalde, A.; Papale, E.; Aniceto, S.; Buscaino, G.; Rasmussen, M.; Matias, L.; Prieto, R.; Silva, M. A.
10.1101/2022.10.05.510968 — animal behavior and cognition — Posted on 2022-10-10
3017 Mapping connectivity and conservation opportunity on agricultural lands across the conterminous United States
Suraci, J. P.; Littlefield, C. E.; Nicholson, C. C.; Hunter, M. C.; Sorensen, A.; Dickson, B. G.
10.1101/2022.10.08.511378 — ecology — Posted on 2022-10-10
3018 Multidisciplinary approach to the study of artworks: environmental conditions, color palette, microbial colonization and nannofossils in Las Musas painting
Calderon-Mesen, P.; Jaikel-Viquez, D.; Barrantes-Madrigal, M. D.; Sanchez-Solis, J.; Mena-Vega, J.; Arguedas-Molina, J.; Urena-Alvarado, K.; Maynard-Hernandez, G.; Santamaria-Montero, L.; Cob-Delgado, M.; Angulo-Pardo, E.; Vallejo, F.; Sandoval-Gutierrez, M.; Duran-Quesada, A.; Redondo-Solano, M.; Herrera-Sancho, O. A.
10.1101/2022.10.05.511059 — microbiology — Posted on 2022-10-10
3019 Evidence for a Spoken Word Lexicon in the Auditory Ventral Stream
Damera, S. R.; Chang, L.; Nikolov, P. P.; Mattei, J. A.; Banerjee, S.; Glezer, L. S.; Cox, P. H.; Jiang, X.; Rauschecker, J. P.; Riesenhuber, M.; Riesenhuber, M.
10.1101/2022.10.09.511436 — neuroscience — Posted on 2022-10-10
3020 Multifunctional fibers enable modulation of cortical and deep brain activity during cognitive behavior in macaques
Garwood, I. C.; Major, A. J.; Antonini, M.-J.; Correa, J.; Lee, Y.; Sahasrabudhe, A.; Mahnke, M. K.; Miller, E. K.; Brown, E. N.; Anikeeva, P.
10.1101/2022.10.09.511302 — neuroscience — Posted on 2022-10-10
3021 Generalized habitual tendencies in alcohol dependent rats
Giannone, F.; Hach, A.; Chroszcz, M.; Friske, M. M.; Meinhardt, M. W.; Spanagel, R.; Sommer, W. H.; Hansson, A. C.
10.1101/2022.10.04.510642 — neuroscience — Posted on 2022-10-10
3024 GTF2I dosage regulates neuronal differentiation and social behavior in 7q11.23 neurodevelopmental disorders
Lopez-Tobon, A.; Shyti, R.; Villa, C. E.; Cheroni, C.; Fuentes-Bravo, P.; Trattaro, S.; Caporale, N.; Troglio, F.; Tenderini, E.; Mihailovich, M.; Skaros, A.; Gibson, W. T.; Cuomo, A.; Bonaldi, T.; Mercurio, C.; Varasi, M.; Osborne, L. R.; Testa, G.
10.1101/2022.10.10.511434 — neuroscience — Posted on 2022-10-10
3027 Autophagy in parvalbumin interneurons is required for inhibitory transmission and memory via regulation of synaptic proteostasis
Chalatsi, T.; Fernandez, L. M. J.; Scholler, J.; Batti, L.; Kolaxi, A.; Restivo, L.; Luthi, A.; Mameli, M.; Nikoletopoulou, V.
10.1101/2022.10.10.511533 — neuroscience — Posted on 2022-10-10
3028 7q11.23 CNV alters protein synthesis and REST-mediated neuronal intrinsic excitability
Mihailovich, M.; Germain, P.-L.; Shyti, R.; Pozzi, D.; Noberini, R.; Liu, Y.; Aprile, D.; Tenderini, E.; Troglio, F.; Trattaro, S.; Fabris, S.; Ciptasari, U.; Rigoli, M. T.; Caporale, N.; D Agostino, G.; Vitriolo, A.; Capocefalo, D.; Skaros, A.; Franchini, A.; Ricciardi, S.; Biunno, I.; Neri, A.; Kasri, N. N.; Bonaldi, T.; Aebersold, R.; Matteoli, M.; Testa, G.
10.1101/2022.10.10.511483 — neuroscience — Posted on 2022-10-10
3029 Frugal alignment-free identification of FLT3-internal tandem duplications with FiLT3r
Boudry, A.; Darmon, S.; Duployez, N.; Figeac, M.; Geffroy, S.; Bucci, M.; Celli-Lebras, K.; Duchmann, M.; Joudinaud, R.; Fenwarth, L.; Nibourel, O.; Goursaud, L.; Itzykson, R.; Dombret, H.; Hunault, M.; Preudhomme, C.; Salson, M.
10.1101/2022.06.27.496265 — bioinformatics — Posted on 2022-10-10
3032 Gut microbiome signatures of Yorkshire Terrier Enteropathy during disease and remission.
Doulidis, P. G.; Galler, A. I.; Hausmann, B.; Berry, D.; Rodriguez Rojas, A.; Burgener, I. A.
10.1101/2022.08.25.505284 — microbiology — Posted on 2022-10-10
3036 Role of a transient access path within ABCG protein involved in a selective transport of legume phenylpropanoids
Pakuła, K.; Sequeiros-Borja, C.; Biała-Leonhard, W.; Pawela, A.; Banasiak, J.; Bailly, A.; Radom, M.; Geisler, M.; Brezovsky, J.; Jasinski, M.
10.1101/2022.08.16.503940 — biochemistry — Posted on 2022-10-10
3040 Residual Complex I activity supports glutamate catabolism and mtSLP via canonical Krebs cycle activity during acute anoxia without OXPHOS
Ravasz, D.; Bui, D.; Nazarian, S.; Pallag, G.; Karnok, N.; Roberts, J.; Tennant, D. A.; Greenwood, B.; Kitayev, A.; Hill, C.; Komlodi, T.; Doerrier, C.; Gnaiger, E.; Kiebish, M. A.; Raska, A.; Kolev, K.; Czumbel, B.; Narain, N. R.; Seyfried, T. N.; Chinopoulos, C.
10.1101/2022.09.26.509156 — biochemistry — Posted on 2022-10-10
3042 Triac treatment prevents neurodevelopmental and locomotor impairments in thyroid hormone transporter Mct8/Oatp1c1 deficient mice
Chen, J.; Salveridou, E.; Liebmann, L.; Sundaram, S. M.; Doycheva, D.; Markova, B.; Huebner, C. A.; Boelen, A.; Visser, W. E.; Heuer, H.; Mayerl, S.
10.1101/2022.10.07.511125 — neuroscience — Posted on 2022-10-10
3043 Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1
Zhao, L.-h.; Yuan, Q.; Dai, A.; Chen, C.-W.; He, X.; Zhang, C.; Xu, Y.; Zhou, Y.; Wang, M.-W.; Yang, D.; Xu, H. E.
10.1101/2022.10.09.511452 — biochemistry — Posted on 2022-10-09
3049 Proteomics of resilience to Alzheimer's disease identifies brain regional soluble Aβ levels, actin filament processes, and response to injury
Huang, Z.; Merrihew, G. E.; Larson, E. B.; Park, J.; Plubell, D.; Fox, E. J.; Montine, K. S.; Keene, C. D.; Zou, J.; MacCoss, M. J.; Montine, T. J.
10.1101/2022.10.09.511430 — neuroscience — Posted on 2022-10-09
3050 Molecular and genetic mechanisms conferring dissolution of dioecy in Diospyros oleifera Cheng
Sun, P.; Nishiyama, S.; Li, H.; Mai, Y.; Han, W.; Suo, Y.; Liang, C.; Du, H.; Diao, S.; Wang, Y.; Yuan, J.; Zhang, Y.; Tao, R.; Li, F.; Fu, J.
10.1101/2022.10.08.511238 — plant biology — Posted on 2022-10-09
3052 Spatially Multiplexed Single-molecule Translocations through a Nanopore at Controlled Speeds
Leitao, S. M.; Navikas, V.; Miljkovic, H.; Drake, B.; Marion, S.; Pistoletti, G.; Chen, K.; Mayer, S.; Keyser, U. F.; Kuhn, A.; Fantner, G. E.; Radenovic, A.
10.1101/2022.10.08.511427 — biophysics — Posted on 2022-10-09
3053 Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1
Zhao, L.-h.; Yuan, Q.; Dai, A.; Chen, C.-W.; He, X.; Zhang, C.; Xu, Y.; Zhou, Y.; Wang, M.-W.; Yang, D.; Xu, H. E.
10.1101/2022.10.09.511452 — biochemistry — Posted on 2022-10-09
3054 Metagenomic analysis unravels novel taxonomic differences in the uterine microbiome between healthy mares and mares with endometritis
Virendra, A.; Gulavane, S. U.; Ahmed, Z. A.; Reddy, R.; Chaudhari, R. J.; Gaikwad, S. M.; Shelar, R. R.; Ingole, S. D.; Thorat, V. D.; Khanam, A.; Khan, F. A.
10.1101/2022.10.09.511479 — genomics — Posted on 2022-10-09
3057 Domino-like Effect of C112R Mutation on APOE4 Aggregation and Its Suppression by Alzheimer's Disease Drug Candidate
Nemergut, M.; Marques, S. M.; Uhrik, L.; Vanova, T.; Nezvedova, M.; Gadara, D. C.; Jha, D.; Tulis, J.; Novakova, V.; Iglesias-Planas, J.; Kunka, A.; Legrand, A.; Hribkova, H.; Pospisilova, V.; Sedmik, J.; Raska, J.; Prokop, Z.; Damborsky, J.; Bohaciakova, D.; Spacil, Z.; Hernychova, L.; Bednar, D.; Marek, M.
10.1101/2022.10.09.511473 — neuroscience — Posted on 2022-10-09
3058 Longitudinal investigation of changes in resting-state co-activation patterns and their predictive ability in the zQ175 DN mouse model of Huntington's disease
Adhikari, M. H.; Vasilkovska, T.; Cachope, R.; Tang, H.; Liu, L.; Keliris, G. A.; Munoz-Sanjuan, I.; Pustina, D.; Van Der Linden, A.; Verhoye, M.
10.1101/2022.10.09.511485 — neuroscience — Posted on 2022-10-09
3060 Entorhinal grid-like codes and time-locked network dynamics track others navigating through space
Wagner, I. C.; Graichen, L.; Todorova, B.; Luettig, A.; Omer, D.; Stangl, M.; Lamm, C.
10.1101/2022.10.08.511403 — neuroscience — Posted on 2022-10-09
3063 Live Cell Lineage Tracing of Dormant Cancer Cells
Kim, H.; Wirasaputra, A.; Kundu, A. N.; Esteves, J.; Peyton, S.
10.1101/2022.10.08.511405 — bioengineering — Posted on 2022-10-09
3064 Differences in activity and stability drive transposable element variation in tropical and temperate maize.
Ou, S.; Collins, T.; Qiu, Y.; Seetharam, A. S.; Menard, C. C.; Manchanda, N.; Gent, J. I.; Schatz, M. C.; Anderson, S. N.; Hufford, M. B.; Hirsch, C. N.
10.1101/2022.10.09.511471 — genomics — Posted on 2022-10-09
3065 Temperature-induced methylome changes during asexual reproduction trigger transcriptomic and phenotypic changes in Fragaria vesca
Zhang, Y.; Fan, G.; Toivainen, T.; Tengs, T.; Yakovlev, I.; Krokene, P.; Hytonen, T.; Fossdal, C. G.; Grini, P. E.
10.1101/2022.10.09.511489 — genomics — Posted on 2022-10-09
3066 High-resolution Nanopore methylome-maps reveal random hyper-methylation at CpG-poor regions as driver of chemoresistance in leukemias.
Magi, A.; Mattei, G.; Mingrino, A.; Caprioli, C.; Ronchini, C.; Frige, G.; Semeraro, R.; Bolognini, D.; Rambaldi, A.; Candoni, A.; Colombo, E.; Mazzarella, L.; Pelicci, P. G.
10.1101/2022.10.09.511472 — genomics — Posted on 2022-10-09
3067 Single-cell DNA methylation sequencing by combinatorial indexing and enzymatic DNA methylation conversion.
Chatterton, Z.; Lamichhane, P.; Rastegar, D. A.; Fitzpatrick, L.; Lebhar, H.; Marquis, C.; Halliday, G.; Kwok, J.
10.1101/2022.10.09.511389 — genomics — Posted on 2022-10-09
3069 ASCL1 interacts with the mSWI/SNF at distal regulatory elements to regulate neural differentiation
Paun, O.; Tan, Y. X.; Patel, H.; Strohbuecker, S.; Ghanate, A.; Cobolli Gigli, C.; Sopena, M. L.; Gerontogianni, L.; Goldstone, R.; Ang, S.-L.; Guillemot, F.; Dias, C.
10.1101/2022.10.09.510609 — developmental biology — Posted on 2022-10-09
3070 Carm1 regulates the speed of C/EBPa-induced transdifferentiation by a cofactor stealing mechanism
Garcia, G. T.; Kowenz-Leutz, E.; Tian, T. V.; Klonizakis, A.; Lerner, J.; De Andres-Aguayo, L.; Berenguer, C.; Carmona, M. P.; Casadesus, M. V.; Bulteau, R.; Francesconi, M.; Peiro, S.; Zaret, K. S.; Leutz, A.; Graf, T.
10.1101/2022.10.03.510647 — cell biology — Posted on 2022-10-09
3072 2,4-Di-tert-butylphenol Induces Adipogenesis in Human Mesenchymal Stem Cells by Activating Retinoid X Receptors
Ren, X.-M.; Chang, R. C.; Huang, Y.; Amato, A. A.; Carivenc, C.; Grimaldi, M.; Kuo, A. Y.; Balaguer, P.; Bourguet, W.; Blumberg, B.
10.1101/2022.10.08.511439 — pharmacology and toxicology — Posted on 2022-10-09
3073 LSD1 acts as an epigenetic barrier against glucocorticoid-induced atrophy and exercise-induced hypertrophy in skeletal muscle
Araki, H.; Hino, S.; Anan, K.; Kuribayashi, K.; Etoh, K.; Seko, D.; Takase, R.; Kohrogi, K.; Hino, Y.; Ono, Y.; Araki, E.; Nakao, M.
10.1101/2022.10.08.509614 — cell biology — Posted on 2022-10-09
3075 Loss of cytoskeletal proteostasis links dysregulation of cell size and mechanotransduction in mesenchymal stem cell senescence
Mallikarjun, V.; Dobre, O.; Jackson, M. R.; Kidd, M.; Llewellyn, J.; Gilbert, H. T.; Richardson, S. M.; Swift, J.
10.1101/2022.10.09.511462 — cell biology — Posted on 2022-10-09
3076 Desmosomal connectomics of all somatic muscles in an annelid larva
Jasek, S.; Veraszto, C.; Brodrick, E.; Shahidi, R.; Kazimiers, T.; Kerbl, A.; Jekely, G.
10.1101/2021.06.09.447732 — animal behavior and cognition — Posted on 2022-10-09
3077 Stomatal regulators are co-opted for seta development in the astomatous liverwort Marchantia polymorpha
Moriya, K. C.; Shirakawa, M.; Loue-Manifel, J.; Matsuda, Y.; Lu, Y.-T.; Tamura, K.; Oka, Y.; Matsushita, T.; Hara-Nishimura, I.; Ingram, G.; Nishihama, R.; Goodrich, J.; Kohchi, T.; Shimada, T.
10.1101/2022.04.29.489008 — plant biology — Posted on 2022-10-09
3078 Comparison of calling pipelines for whole genome sequencing: an empirical study demonstrating the importance of mapping and alignment
Betschart, R.; Thiery, A.; Aguilera-Garcia, D.; Zoche, M.; Moch, H.; Twerenbold, R.; Zeller, T.; Blankenberg, S.; Ziegler, A.
10.1101/2022.09.18.508404 — bioinformatics — Posted on 2022-10-09
3080 A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1
Closa, A.; Reixachs-Sole, M.; Fuentes-Fayos, A. C.; Hayer, K. E.; Melero, J. L.; Adriaanse, F. R.; Bos, R. S.; Torres-Diz, M.; Hunger, S.; Roberts, K. G.; Mullighan, C.; Stam, R. W.; Thomas-Tikhonenko, A.; Castano, J. P.; Luque, R. M.; Eyras, E.
10.1101/2021.12.13.472370 — cancer biology — Posted on 2022-10-09
3083 Protein Language Model Predicts Mutation Pathogenicity and Clinical Prognosis
Liu, X.; Yang, X.; Ouyang, L.; Guo, G.; Su, J.; Xi, R.; Yuan, K.; Yuan, F.
10.1101/2022.09.30.510294 — bioinformatics — Posted on 2022-10-09
3091 Tissue-Specific and Interorgan Metabolic Reprogramming Maintains Tolerance to Sepsis
Leitner, B. P.; Lee, W. D.; Zhu, W.; Zhang, X.; Gaspar, R. C.; Li, Z.; Rabinowitz, J. D.; Perry, R. J.
10.1101/2022.10.08.511411 — physiology — Posted on 2022-10-08
3095 Mitochondria-containing EVs Protect Brain Endothelial Cells and Reduce Mouse Brain Infarct Sizes
Dave, K.; Stolz, D. B.; Venna, V. R.; Quaicoe, V. A.; Maniskas, M. E.; Reynolds, M. J.; Babidhan, R.; Dobbins, D. X.; Farinelli, M. N.; Sullivan, A.; Bhatia, T. N.; Yankello, H.; Reddy, R.; Bae, Y.; Leak, R. K.; Shiva, S.; McCullough, L. D.; Soundara Manickam, D.
10.1101/2021.10.29.466491 — bioengineering — Posted on 2022-10-08
3097 Multigenic resistance to Xylella fastidiosa in wild grapes (Vitis sps.) and its implications within a changing climate
Morales-Cruz, A.; Aguirre-Liguori, J. A.; Massonet, M.; Zaccheo, M.; Minio, A.; Cochetel, N.; Walker, A.; Riaz, S.; Zhou, Y.; Cantu, D.; Gaut, B. S.
10.1101/2022.10.08.511428 — genetics — Posted on 2022-10-08
3099 Lifespan Extension in Female Mice By Early, Transient Exposure to Adult Female Olfactory Cues
Garratt, M.; Erturk, I.; Alonso, R.; Zufall, F.; Leinders-Zufall, T.; Pletcher, S.; Miller, R.
10.1101/2022.10.07.511218 — evolutionary biology — Posted on 2022-10-08
3100 Multiple congenital malformations arise from somatic mosaicism for constitutively active Pik3ca signalling
Marechal, E.; Poliard, A.; Henry, K.; Moreno, M.; Legrix, M.; Macagno, N.; Mondielli, G.; Fauquier, T.; Barlier, A.; Etchevers, H. C.
10.1101/2022.04.05.487130 — developmental biology — Posted on 2022-10-08
3101 The protozoan commensal Tritrichomonas musculis is a natural adjuvant for mucosal IgA.
Cao, E. Y.; Burrows, K.; Chiaranunt, P.; Popovic, A.; Zhou, X.; Xie, C.; Thakur, A.; Britton, G. J.; Spindler, M. P.; Ngai, L.; Tai, S. L.; Dasoveanu, D. C.; Nguyen, A.; Faith, J. J.; Parkinson, J.; Gommerman, J.; Mortha, A.
10.1101/2022.10.08.511442 — immunology — Posted on 2022-10-08
3102 The START domain potentiates HD-ZIPIII transcriptional activity
Husbands, A. Y.; Feller, A.; Aggarwal, V.; Dresden, C. E.; Holub, A. S.; Ha, T.; Timmermans, M. C. P.
10.1101/2022.10.08.511209 — plant biology — Posted on 2022-10-08
3103 Ketone body metabolism declines with age in mice in a sex-dependent manner
Eap, B.; Nomura, M.; Panda, O.; Garcia, T. Y.; King, C. D.; Rose, J. P.; Leone, T. C.; Kelly, D. P.; Schilling, B.; Newman, J. C.
10.1101/2022.10.05.511032 — physiology — Posted on 2022-10-08
3104 Beneficial Effects of Bempedoic Acid Treatment in Polycystic Kidney Disease Cells and Mice
Hallows, K. R.; Li, H.; Saitta, B.; Sepehr, S.; Huang, P.; Pham, J.; Wang, J.; Mancino, V.; Chung, E. J. R.; Pinkosky, S. L.; Pastor-Soler, N. M.
10.1101/2022.08.09.503392 — pathology — Posted on 2022-10-08
3105 The prophylactic value of TNF-alpha inhibitors against retinal ganglion cell and optic nerve axon loss after corneal surgery or trauma
Paschalis, E. I.; Zhou, C.; Sharma, J.; Kim, S.; Lei, F.; Chodosh, J.; Vavvas, D.; Urtti, A.; Papaliodis, G.; Dohlman, C. H.
10.1101/2022.10.06.510713 — pathology — Posted on 2022-10-08
3106 PKC-alpha promotes phosphorylation of KRAS suppressing its oncogenic properties
Joglekar, T.; Ku, A.; Schollaert, E.; Gong, Y.-N.; Stewart-Ornstein, J.; Urisman, A.; Wang, M.-T.
10.1101/2022.05.24.493257 — cancer biology — Posted on 2022-10-08
3110 Implications of taxonomic bias for microbial differential-abundance analysis
McLaren, M. R.; Nearing, J. T.; Willis, A. D.; Lloyd, K. G.; Callahan, B. J.
10.1101/2022.08.19.504330 — bioinformatics — Posted on 2022-10-08
3113 Complex hybridization between deeply diverged fish species in a disturbed ecosystem
Banerjee, S. M.; Powell, D. L.; Moran, B. M.; Ramirez-Duarte, W. F.; Langdon, Q. K.; Gunn, T. R.; Vazquez, G.; Rochman, C.; Schumer, M.
10.1101/2022.10.08.511445 — evolutionary biology — Posted on 2022-10-08
3114 Single Cell Cortical Bone Transcriptomics Defines Novel Osteolineage Gene Sets Altered in Chronic Kidney Disease
Agoro, R.; Nookaew, I.; Noonan, M.; Marambio, Y. G.; Liu, S.; Chang, W.; Gao, H.; Horan, D.; Thompson, W. R.; Xuei, X.; Liu, Y.; Zhang, C.; Robling, A. G.; Bonewald, L. F.; Wan, J.; White, K. E.
10.1101/2022.07.30.502024 — cell biology — Posted on 2022-10-08
3115 An unbiased screen identified the Hsp70-BAG3 complex as a regulator of myosin binding protein C3 stability.
Thompson, A. D.; Wagner, M. J.; Rodriguez, J.; Malhotra, A.; Vander Roest, S.; Lilienthal, U.; Shao, H.; Yob, J.; Prosser, B. L.; Helms, A. S.; Gestwicki, J. E.; Ginsburg, D. E.; Day, S. M.
10.1101/2022.10.08.511444 — cell biology — Posted on 2022-10-08
3117 Integrative dissection of gene regulatory elements at base resolution
Chen, Z.; Javed, N. M.; Moore, M.; Wu, J.; Vinyard, M. E.; Pinello, L.; Najm, F.; Bernstein, B. E.
10.1101/2022.10.05.511030 — molecular biology — Posted on 2022-10-08
3118 Communication between the nucleus and the mitochondria via NDUFS4 alternative splicing in gastric cancer cells
Papadaki, V.; Erpapazoglou, Z.; Kokkori, M.; Rogalska, M.; Tsakiri, E.; Ashktorab, H.; Smoot, D. T.; Papanikolopoulou, K.; Samiotaki, M.; Kafasla, P.
10.1101/2022.10.07.511259 — molecular biology — Posted on 2022-10-08
3122 Does prefrontal connectivity during task switching help or hinder children's performance?
Schwarze, S. A.; Laube, C.; Khosravani, N.; Lindenberger, U.; Bunge, S. A.; Fandakova, Y.
10.1101/2022.10.04.510761 — neuroscience — Posted on 2022-10-08
3123 Connectomics of the Octopus vulgaris vertical lobe provides insight into conserved and novel principles of a memory acquisition network
Bidel, F.; Meirovitch, Y.; Schalek, R. L.; Lu, X.; Pavarino, E. C.; Yang, F.; Peleg, A.; Wu, Y.; Shomrat, T.; Berger, D. R.; Shaked, A.; Lichtman, J. W.; Hochner, B.
10.1101/2022.10.03.510303 — neuroscience — Posted on 2022-10-08
3126 Mutational impact of APOBEC3B and APOBEC3A in a human cell line
Jarvis, M.; Carpenter, M. A.; Temiz, N. A.; Brown, M.; Richards, K.; Argyris, P.; Brown, W.; Yee, D.; Harris, R. S.
10.1101/2022.04.26.489523 — cancer biology — Posted on 2022-10-08
3127 The RNA m6A reader YTHDF1 promotes hematopoietic malignancy by maintaining oncogenic translation
Gao, X.; Chen, Z.; Hong, Y.-G.; Yang, Z.; Chen, Y.; Liu, T.; Zheng, Y.; Wu, G.-C.; Chen, Y.; Xia, J.; Wen, R.; Zhao, Y.; Chen, J.
10.1101/2022.10.08.511406 — cancer biology — Posted on 2022-10-08
3129 Dynamic matrices with DNA-encoded viscoelasticity for advanced cell and organoid culture
Peng, Y.-H.; Gupta, K.; Hsiao, S.-K.; Ruland, A.; Auernhammer, G. K.; Maitz, M. F.; Boye, S.; Gerri, C.; Honigmann, A.; Werner, C.; Krieg, E.
10.1101/2022.10.08.510936 — bioengineering — Posted on 2022-10-08
3130 AI-guided cryo-EM probes a thermophilic cell-free system with succinyl-coA manufacturing capability
Skalidis, I.; Kyrilis, F. L.; Tueting, C.; Hamdi, F.; Traeger, T. K.; Belapure, J.; Hause, G.; Fratini, M.; O'Reilly, F. J.; Heilmann, I.; Rappsilber, J.; Kastritis, P. L.
10.1101/2022.10.08.511438 — biochemistry — Posted on 2022-10-08
3132 Feedback-based motor control can guide plasticity and drive rapid learning
Feulner, B.; Perich, M. G.; Miller, L. E.; Clopath, C.; Gallego, J. A.
10.1101/2022.10.06.511108 — neuroscience — Posted on 2022-10-08
3134 Inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution.
Marx, S. K.; Mickolajczyk, K. J.; Craig, J. M.; Thomas, C. A.; Pfeffer, A. M.; Abell, S. J.; Carrasco, J. D.; Franzi, M. C.; Huang, J. R.; Kim, H. C.; Brinkerhoff, H. D.; Kapoor, T. M.; Gundlach, J. H.; Laszlo, A. H.
10.1101/2022.10.07.511351 — biophysics — Posted on 2022-10-08
3135 SiRNA Molecules as Potential RNAi Therapeutics to Silence RdRP Region and N-Gene of SARS-CoV-2: An In Silico Approach
Hasan, M.; Tasnim, A. T.; Ashik, A. I.; Chowdhury, M. B.; Nishat, Z. S.; Fariha, K. A.; Hossain, T.; Ahmed, S.
10.1101/2022.10.08.511397 — bioinformatics — Posted on 2022-10-08
3138 Hyperactive mTOR in Lung Mesenchyme Induces Endothelial Dysfunction and Pulmonary Vascular Remodeling
Lin, S. M.; Rue, R.; Goel, A.; Obraztsova, K.; Mukhitov, A. R.; Vanka, K. S.; Smith, C. J.; Basil, M. C.; Ferguson, L. T.; Planer, J. D.; Cantu, E.; Morrisey, E. E.; Evans, J. F.; Krymskaya, V. P.
10.1101/2022.10.08.511300 — molecular biology — Posted on 2022-10-08
3140 Inflammation Of The Retinal Pigment Epithelium Drives Early-Onset Photoreceptor Degeneration In Mertk-Associated Retinitis Pigmentosa
Mercau, M. E.; Akalu, Y. T.; Mazzoni, F.; Gyimesi, G.; Alberto, E. J.; Kong, Y.; Hafler, B.; Finnemann, S. C.; Rothlin, C. V.; Ghosh, S.
10.1101/2022.10.08.511415 — immunology — Posted on 2022-10-08
3145 An alternative mechanism for skeletal muscle dysfunction in long-term post-viral lung disease
Martin, R. A.; Keeler, S. P.; Wu, K.; Shearon, W. J.; Patel, D.; Hoang, M.; Hoffmann, C. M.; Hughes, M. E.; Holtzman, M. J.
10.1101/2022.10.07.511313 — physiology — Posted on 2022-10-08
3148 MAST: Phylogenetic Inference with Mixtures Across Sites and Trees
Wong, T. K. F.; Cherryh, C.; Rodrigo, A. G.; Hahn, M. W.; Minh, B. Q.; Lanfear, R.
10.1101/2022.10.06.511210 — bioinformatics — Posted on 2022-10-08
3151 Fast computation of principal components of genomic similarity matrices
Hahn, G.; Lutz, S.; Hecker, J.; Prokopenko, D.; Cho, M.; Silverman, E. K.; Weiss, S. T.; Lange, C.
10.1101/2022.10.06.511168 — bioinformatics — Posted on 2022-10-08
3160 Improving polygenic risk prediction in admixed populations by explicitly modeling ancestral-specific effects via GAUDI
Sun, Q.; Rowland, B. T.; Chen, J.; Mikhaylova, A. V.; Avery, C.; Peters, U.; Lundin, J.; Matise, T.; Buyske, S.; Tao, R.; Mathias, R. A.; Reiner, A. P.; Auer, P. L.; Cox, N. J.; Kooperberg, C.; Thornton, T.; Raffield, L. M.; Li, Y.
10.1101/2022.10.06.511219 — genetics — Posted on 2022-10-08
3162 Biogeography of human-health associated butyrate-producing bacteria
Brame, J. E.; Liddicoat, C.; Abbott, C. A.; Edwards, R. A.; Robinson, J. M.; Gauthier, N. E.; Breed, M. F.
10.1101/2022.10.07.510278 — ecology — Posted on 2022-10-08
3165 Pseudomonas aeruginosa can diversify after host cell invasion to establish multiple intracellular niches
Kumar, N. G.; Nieto, V.; Kroken, A. R.; Jedel, E.; Grosser, M. R.; Hallsten, M. E.; Metruccio, M. M. E.; Yahr, T. L.; Evans, D. J.; Fleiszig, S. M. J.
10.1101/2022.10.07.511388 — microbiology — Posted on 2022-10-08
3166 BamQuery: a proteogenomic tool for the genome-wide exploration of the immunopeptidome
Ruiz Cuevas, M. V.; Hardy, M.-P.; Larouche, J.-D.; Apavaloaei, A.; Kina, E.; Vincent, K.; Gendron, P.; Laverdure, J.-P.; Durette, C.; Thibault, P.; Lemieux, S.; Perreault, C.; Ehx, G.
10.1101/2022.10.07.510944 — immunology — Posted on 2022-10-08
3167 Dietary restriction of isoleucine increases healthspan and lifespan of genetically heterogeneous mice
Green, C. L.; Trautman, M. E.; Babygirija, R.; Jain, R.; Chaiyakul, K.; Pak, H. H.; Bleicher, A.; Novak, G.; Sonsalla, M. M.; Yeh, C.-Y.; Calubag, M. F.; Liu, T. T.; Flores, V.; Newman, S.; Ricke, W. A.; Matkowskyj, K. A.; Ong, I. M.; Simcox, J.; Lamming, D.
10.1101/2022.10.06.511051 — physiology — Posted on 2022-10-08
3169 UV irradiation remodels the specificity landscape of transcription factors
Mielko, Z.; Zhang, Y.; Liu, Y.; Schaich, M. A.; Schnable, B.; Burdinski, D.; Adar, S.; Pufall, M.; Van Houten, B.; Gordan, R.; Afek, A.
10.1101/2022.10.07.511343 — biophysics — Posted on 2022-10-08
3170 EquiFold: Protein Structure Prediction with a Novel Coarse-Grained Structure Representation
Lee, J. H.; Yadollahpour, P.; Watkins, A.; Frey, N. C.; Leaver-Fay, A.; Ra, S.; Cho, K.; Gligorijevic, V.; Regev, A.; Bonneau, R.
10.1101/2022.10.07.511322 — bioinformatics — Posted on 2022-10-08
3172 Structure-Aware Antibiotic Resistance Classification Using Graph Neural Networks
Qabel, A.; Ennadir, S.; Nikolentzos, G.; Lutzeyer, J. F.; Chatzianastasis, M.; Bostrom, H.; Vazirgiannis, M.
10.1101/2022.10.06.511103 — bioinformatics — Posted on 2022-10-08
3174 Elephants have an adaptable prehensile grip
Schulz, A. K.; Reidenberg, J.; Wu, J.; Tang, C. Y.; Seleb, B.; Mancebo, J.; Elgart, N.; Hu, D. L.
10.1101/2022.10.06.511214 — bioengineering — Posted on 2022-10-08
3177 Causal Epigenetic Age Uncouples Damage and Adaptation
Ying, K.; Liu, H.; Tarkhov, A. E.; Lu, A. T.; Horvath, S.; Kutalik, Z.; Shen, X.; Gladyshev, V. N.
10.1101/2022.10.07.511382 — genetics — Posted on 2022-10-08
3178 Impact of Holocene environmental change on the evolutionary ecology of an Arctic top predator
Westbury, M. V.; Brown, S. C.; Lorenzen, J.; O'Neill, S.; Scott, M.; McCuaig, J.; Cheung, C.; Armstrong, E.; Valdes, P. J.; Alfredo Samaniego Castruita, J.; Cabrera, A. A.; Keibel Blom, S.; Dietz, R.; Sonne, C.; Louis, M.; Galatius, A.; Fordham, D. A.; Ribeiro, S.; Szpak, P.; Lorenzen, E.
10.1101/2022.10.06.511126 — evolutionary biology — Posted on 2022-10-08
3183 The deep-sea coral, Callogorgia delta, associates with bacteria belonging to a novel marine branch of the Mollicutes
Vohsen, S. A.; Gruber-Vodicka, H. R.; Meyer, M.; Sadowski, M.; Dubilier, N.; Fisher, C. R.; Baums, I. B.
10.1101/2022.10.07.511369 — microbiology — Posted on 2022-10-08
3185 Tight control of the APP-Mint1 interaction in regulating amyloid production
Henry, S. M.; Bartling, C. R. O.; Stromgaard, K.; Beffert, U.; Ho, A.
10.1101/2022.10.07.511363 — neuroscience — Posted on 2022-10-08
3186 Horizontally transferred genes as RNA interference targets for aphid and whitefly control
Feng, H.; Chen, W.; Hussain, S.; Shakir, S.; Tzin, V.; Adegbayi, F.; Ugine, T.; Fei, Z.; Jander, G.
10.1101/2022.10.07.511359 — plant biology — Posted on 2022-10-08
3189 MRPS36 provides a missing link in the eukaryotic 2-oxoglutarate dehydrogenase complex for recruitment of E3 to the E2 core
Hevler, J. f.; Albanese, P.; Cabrera-Orefice, A.; Potter, A.; Jankevics, A.; Misic, J.; Scheltema, R. A.; Brandt, U.; Arnold, S.; Heck, A. J. R.
10.1101/2022.10.08.511390 — biochemistry — Posted on 2022-10-08
3190 Streetlights affect moth orientation beyond flight-to-light behaviour
Degen, J.; Storms, M.; Lee, C. B.; Jechow, A.; Stoeckl, A. L.; Hoelker, F.; Jakhar, A.; Walter, T.; Walter, S.; Mitesser, O.; Hovestadt, T.; Degen, T.
10.1101/2022.10.06.511092 — animal behavior and cognition — Posted on 2022-10-08
3191 Epigenomic and chromosomal architectural reconfiguration in developing human frontal cortex and hippocampus
Heffel, M. G.; Zhou, J.; Zhang, Y.; Lee, D.-S.; Hou, K.; Pastor Alonso, O.; Abuhanna, K.; Schmitt, A. D.; Li, T.; Haeussler, M.; Wick, B.; Zhang, M. J.; Xie, F.; Ziffra, R. S.; Mukamel, E. A.; Eskin, E.; Pasaniuc, B.; Ecker, J. R.; Dixon, J.; Nowakowski, T. J.; Paredes, M. F.; Luo, C.
10.1101/2022.10.07.511350 — genomics — Posted on 2022-10-08
3194 Network Segregation Predicts Processing Speed in the Cognitively Healthy Oldest-old
Nolin, S. A.; Faulkner, M. E.; Stewart, P.; Merritt, S.; Rezaei, R. F.; Bharadwaj, P. K.; Franchetti, M. K.; Raichlen, D. A.; Jessup, C. J.; Hishaw, G. A.; Van Etten, E. J.; Trouard, T. P.; Geldmacher, D.; Wadley, V. G.; Alperin, N.; Porges, E. S.; Woods, A. J.; Cohen, R. A.; Levin, B. E.; Rundek, T.; Alexander, G. E.; Visscher, K. M.
10.1101/2021.10.05.463207 — neuroscience — Posted on 2022-10-08
3197 Commitment in the Pink1/Parkin mitophagy decision circuit
Waters, C. S.; Angenent, S. B.; Altschuler, S. J.; Wu, L. F.
10.1101/2022.10.07.510659 — systems biology — Posted on 2022-10-07
3200 Targeting tumour-intrinsic neural vulnerabilities of glioblastoma
Lee, S.; Weiss, T.; Buehler, M.; Mena, J.; Lottenbach, Z.; Wegmann, R.; Bihl, M.; Augustynek, B.; Baumann, S.; Goetze, S.; van Drogen, A.; Rushing, E. J.; Wollscheid, B.; Hediger, M. A.; Weller, M.; Snijder, B.
10.1101/2022.10.07.511321 — cancer biology — Posted on 2022-10-07
3201 Cell division history encodes directional information of fate transitions
Wang, K.; Hou, L.; Lu, Z.; Wang, X.; Zi, Z.; Zhai, W.; He, X.; Curtis, C.; Zhou, D.; Hu, Z.
10.1101/2022.10.06.511094 — genomics — Posted on 2022-10-07
3203 Adhesion of Crithidia fasciculata promotes a rapid change in developmental fate driven by cAMP signaling
Denecke, S.; Malfara, M. F.; Hodges, K. R.; Holmes, N. A.; Williams, A. R.; Gallagher-Teske, J. H.; Pascarella, J. M.; Daniels, A. M.; Sterk, G. J.; Leurs, R.; Ruthel, G.; Hoang, R.; Povelones, M. L.; Povelones, M.
10.1101/2022.10.06.511084 — microbiology — Posted on 2022-10-07
3205 Tuning of cytokine signaling through imbalanced abundances of receptors and kinases
Sta, L.; Voisinne, G.; Cotari, J.; Adamer, M.; Molina-Paris, C.; Altan-Bonnet, G.
10.1101/2022.10.07.511173 — systems biology — Posted on 2022-10-07
3206 A Novel Mouse Model that Recapitulates the Heterogeneity of Human Triple Negative Breast Cancer
Doha, Z. O.; Wang, X.; Calistri, N.; Eng, J.; Daniel, C. J.; Ternes, L.; Kim, E. N.; Pelz, C.; Munks, M.; Betts, C.; Kirchberger, N.; Kwon, S.; Bucher, E.; Li, X.; Waugh, T.; Pietenpol, J. A.; Sanders, M. E.; Mills, G. B.; Chin, K.; Chang, Y. H.; Coussens, L. M.; Gray, J. W.; Heiser, L.; Sears, R. C.
10.1101/2022.10.07.511231 — cancer biology — Posted on 2022-10-07
3207 Dissecting infant leukemia developmental origins with a hemogenic gastruloid model
Ragusa, D.; Suen, C. W.; Torregrosa Cortes, G.; Dijkhuis, L.; Byrne, C.; Ionescu, G.-A.; Cerveira, J.; Kranc, K. R.; Bigas, A.; Garcia-Ojalvo, J.; Martinez Arias, A.; Pina, C.
10.1101/2022.10.07.511362 — developmental biology — Posted on 2022-10-07
3209 Spatially-enhanced clusterwise inference for testing and localizing intermodal correspondence
Weinstein, S. M.; Vandekar, S. N.; Baller, E. B.; Tu, D.; Adebimpe, A.; Tapera, T. M.; Gur, R. C.; Gur, R. E.; Detre, J. A.; Raznahan, A.; Alexander-Bloch, A. F.; Satterthwaite, T. D.; Shinohara, R.; Park, J. Y.
10.1101/2022.04.25.489462 — neuroscience — Posted on 2022-10-07
3212 Widespread chromatin context-dependencies ofDNA double-strand break repair proteins
Vergara, X.; Manjon, A. G.; Morris, B.; Schep, R.; Leemans, C.; Sanders, M. A.; Beijersbergen, R. L.; Medema, R. H.; van Steensel, B.
10.1101/2022.10.07.511243 — molecular biology — Posted on 2022-10-07
3213 Microbiome network connectivity and composition linked to disease resistance in strawberry plants
Hassani, M. A.; Gonzalez, O.; Hunter, S. S.; Holmes, G. J.; Hewavitharana, S. S.; Ivors, K.; Lazcano, C.
10.1101/2022.10.07.511207 — microbiology — Posted on 2022-10-07
3214 Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9
Martin, G.; Fernandez Quintero, M. L.; Lee, W.-H.; Pholcharee, T.; Eshun-Wilson, L.; Liedl, K. R.; Pancera, M.; Seder, R. A.; Wilson, I. A.; Ward, A. B.
10.1101/2022.10.07.511358 — immunology — Posted on 2022-10-07
3215 Free-water volume fraction increases non-linearly with age in the white matter of the healthy human brain
Pieciak, T.; Paris, G.; Beck, D.; Maximov, I.; Tristan-Vega, A.; de Luis-Garcia, R.; Westlye, L. T.; Aja-Fernandez, S.
10.1101/2022.10.06.510800 — neuroscience — Posted on 2022-10-07
3221 The methyltransferases METTL7A and METTL7B confer resistance to thiol-based histone deacetylase inhibitors
Robey, R. W.; Fitzsimmons, C. M.; Guiblet, W. M.; Frye, W. J. E.; Gonzalez Dalmasy, J.; Wang, L.; Huff, L. M.; Ali-Rahmani, F.; Lipsey, C. C.; Wade, H. M.; Mitchell, A. V.; Maligireddy, S. S.; Jenkins, L. M.; Nikitina, T.; Zhurkin, V. B.; Piscopio, A. D.; Bates, S. E.; Arda, H. E.; Gottesman, M. M.; Batista, P. J.
10.1101/2022.10.07.511310 — cancer biology — Posted on 2022-10-07
3222 Mnx1 Induces Leukemia Transformation Through Altering Histone Methylation in a Model of Pediatric Acute Myeloid Leukemia with t(7;12)(q36;p13)
Waraky, A.; Ostlund, A.; Nilsson, T.; Weichenhan, D.; Lutsik, P.; Baehr, M.; Hey, J.; Adamsson, J.; Morsy, M. H. A.; Li, S.; Fogelstrand, L.; Plass, C.; Palmqvist, L.
10.1101/2022.06.10.495634 — cancer biology — Posted on 2022-10-07
3224 A geometric approach to quantifying the neuromodulatory effects of persistent inward currents on single motor unit discharge patterns
Beauchamp, J. A.; Pearcey, G. E. P.; Khurram, O. U.; Chardon, M.; Wang, C.; Powers, R. K.; Dewald, J. P. A.; Heckman, C.
10.1101/2022.10.06.511149 — bioengineering — Posted on 2022-10-07
3226 Clearance of genome-damaged cells from the hematopoietic system via p53 without contribution by the cGAS/STING axis
Dressel, N.; Natusch, L.; Munz, C.; Costas-Ramon, S.; Morcos, M. N. F.; Loff, A.; Hiller, B.; Luksch, H.; Roesen-Wolff, A.; Roers, A.; Behrendt, R.; Gerbaulet, A.
10.1101/2022.06.24.497496 — cell biology — Posted on 2022-10-07
3227 Alternative splicing liberates a cryptic cytoplasmic isoform of mitochondrial MECR that antagonizes influenza virus
Baker, S. F.; Meistermann, H.; Tzouros, M.; Baker, A.; Golling, S.; Polster, J. S.; Ledwith, M. P.; Gitter, A.; Augustin, A.; Javanbakht, H.; Mehle, A.
10.1101/2020.11.09.355982 — microbiology — Posted on 2022-10-07
3228 Strong pathogen competition in neonatal gut colonisation
Mäklin, T.; Thorpe, H. A.; Pöntinen, A. K.; Gladstone, R. A.; Shao, Y.; Pesonen, M.; McNally, A.; Johnsen, P. J.; Samuelsen, O.; Lawley, T. D.; Honkela, A.; Corander, J.
10.1101/2022.06.19.496579 — microbiology — Posted on 2022-10-07
3229 Monocyte intrinsic NOD2 signalling inhibits pathogenic macrophage differentiation and its loss in inflammatory macrophages improves intestinal inflammation.
Chauvin, C.; Alvarez, D.; Radulovic, K.; Boulard, O.; Laine, W.; Delacre, M.; Waldschmitt, N.; Segura, E.; Kluza, J.; Chamaillard, M.; Poulin, L. F.
10.1101/2022.10.06.506772 — immunology — Posted on 2022-10-07
3232 A novel porcine model of CLN3 Batten disease recapitulates clinical phenotypes
Swier, V. J.; White, K. A.; Johnson, T. B.; Wang, X.; Han, J.; Pearce, D.; Singh, R.; Rogers, C. S.; Brudvig, J.; Weimer, J. M.
10.1101/2022.10.07.511360 — neuroscience — Posted on 2022-10-07
3233 The representation of priors and decisions in parietal cortex
Marshall, T. R.; Ruesseler, M.; Hunt, L. T.; O'Reilly, J. X.
10.1101/2021.05.03.442155 — neuroscience — Posted on 2022-10-07
3234 ASD gene Bcl11a regulates subcellular RNA localization, associative circuitry, and social behavior
Durak, O.; Kim, J.-Y.; Tillman, D. E.; Itoh, Y.; Wettstein, M. R.; Greig, L. C.; Addison, T. A.; Macklis, J. D.
10.1101/2022.10.06.511159 — neuroscience — Posted on 2022-10-07
3235 Inter-individual variation in human cortical cell type abundance and expression
Johansen, N.; Somasundaram, S.; Travaglini, K. J.; Yanny, A. M.; Shumyatcher, M.; Casper, T.; Cobbs, C.; Dee, N.; Ellenbogen, R.; Ferreira, M.; Goldy, J.; Guzman, J.; Gwinn, R.; Hirschstein, D.; Jorstad, N. L.; Keene, C. D.; Ko, A.; Levi, B. P.; Ojemann, J. G.; Pham, T.; Shapovalova, N.; Silbergeld, D.; Sulc, J.; Torkelson, A.; Tung, H.; Smith, K.; Lein, E. S.; Bakken, T. E.; Hodge, R. D.; Miller, J. A.
10.1101/2022.10.07.511366 — neuroscience — Posted on 2022-10-07
3237 Temporal derivative computation in the dorsal raphe network revealed by an experimentally-driven augmented integrate-and-fire modeling framework
Harkin, E. F.; Lynn, M. B.; Payeur, A.; Boucher, J.-F.; Caya-Bissonnette, L.; Cyr, D.; Stewart, C.; Longtin, A.; Naud, R.; Beïque, J.-C.
10.1101/2021.06.25.449907 — neuroscience — Posted on 2022-10-07
3238 Profiling neurons surrounding subcellular-scale carbon fiber electrode tracts enables modeling recorded signals
Letner, J. G.; Patel, P. R.; Hsieh, J.-C.; Smith Flores, I. M.; Della Valle, E.; Walker, L. A.; Weiland, J. D.; Chestek, C. A.; Cai, D.
10.1101/2022.10.07.511373 — neuroscience — Posted on 2022-10-07
3240 S-nitrosylation of Aux/IAA protein represses auxin signaling
Jing, H.; Yang, X.; Feng, J.; Zhang, J.; Strader, L.; Zuo, J.
10.1101/2022.10.07.511298 — plant biology — Posted on 2022-10-07
3241 Development of Enterovirus anti-viral agents that target the viral 2C protein
Kejriwal, R.; Evans, T.; Calabrese, J.; Swistak, L.; Alexandrescu, L.; Cohen, M.; Rahman, N.; Henriksen, N.; Dash, R. C.; Hadden, K.; Stonehouse, N. J.; Rowlands, D. J.; Kingston, N. J.; Hartnoll, M.; Dobson, S.; White, S.
10.1101/2022.10.06.511132 — pharmacology and toxicology — Posted on 2022-10-07
3242 PKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy
Yoshida, T.; Latt, K. Z.; Rosenberg, A. Z.; Santo, B. A.; Myakala, K.; Ishimoto, Y.; Zhao, Y.; Shrivastav, S.; Jones, B. A.; Yang, X.; Wang, X.; Tutino, V. M.; Sarder, P.; Levi, M.; Okamoto, K.; Winkler, C. A.; Kopp, J. B.
10.1101/2022.10.03.510678 — pathology — Posted on 2022-10-07
3243 Anticancer drug doxorubicin spontaneously reacts with GTP and dGTP
Mejia, G.; Su, L.; Pandey, P.; Dit Fouque, K. J.; McGoron, A.; Fernandez-Lima, F.; He, J.; Mebel, A.; Leng, F.
10.1101/2022.10.07.511347 — cancer biology — Posted on 2022-10-07
3245 Intracellular FUS protein accumulation leads to cytoskeletal, organelle and cellular homeostasis perturbations
Chung, C. W.; Zhou, A. J.; Mela, I.; Stephens, A. D.; Miyashita, A.; St George-Hyslop, P. H.; Kaminski, C. F.; Knowles, T.; Kaminski Schierle, G. S.
10.1101/2022.10.04.510756 — biophysics — Posted on 2022-10-07
3247 Cell division history encodes directional information of fate transitions
Wang, K.; Hou, L.; Lu, Z.; Wang, X.; Zi, Z.; Zhai, W.; He, X.; Curtis, C.; Zhou, D.; Hu, Z.
10.1101/2022.10.06.511094 — genomics — Posted on 2022-10-07
3248 Epigenetic CpG Duplex Marks Probed by an Evolved DNA Reader via a Well-Tempered Conformational Plasticity
Singh, H.; Das, C. K.; Buchmuller, B. C.; Eppmann, S.; Schäfer, L. V.; Summerer, D.; Linser, R.
10.1101/2022.10.06.511192 — genomics — Posted on 2022-10-07
3249 Live imaging reveals chromatin compaction transitions and dynamic transcriptional bursting during stem cell differentiation in vivo
May, D.; Yun, S.; Gonzalez, D.; Park, S.; Chen, Y.; Lathrop, E.; Cai, B.; Xin, T.; Zhao, H.-y.; Wang, S.; Gonzalez, L. E.; Cockburn, K.; Greco, V.
10.1101/2022.10.07.511316 — genetics — Posted on 2022-10-07
3253 A switch in jaw form-function coupling during the evolution of mammals
Tseng, J.; Garcia-Lara, S.; Flynn, J. J.; Holmes, E.; Rowe, T. B.; Dickson, B. V.
10.1101/2022.10.06.511001 — evolutionary biology — Posted on 2022-10-07
3255 A Canine Model of Chronic Ischemic Heart Failure
Khan, M. S.; Smego, D.; Ishidoya, Y.; Hirahara, A.; Offei, E.; Castillo, S.; Gharbia, O.; Palatinus, J.; Krueger, L.; Hong, T.; Hoareau, G.; Ranjan, R.; Selzman, C.; Dosdall, D. J.; Shaw, R.
10.1101/2022.10.07.511342 — developmental biology — Posted on 2022-10-07
3256 A single amino acid change drives left- right asymmetry in Bilateria
Truchado-Garcia, M.; Perry, K. J.; Cavodeassi, F.; Kenny, N. J.; Henry, J. Q.; Grande, C.
10.1101/2022.10.06.511172 — developmental biology — Posted on 2022-10-07
3258 The formation and closure of macropinocytic cups in a model system
Lutton, J.; coker, h.; Paschke, P.; Munn, C.; King, J. S.; Kay, R.; Bretschneider, T.
10.1101/2022.10.07.511330 — cell biology — Posted on 2022-10-07
3260 PLK-1 tethered on BUB-1 directs CDC-20 kinetochore recruitment to ensure timelyembryonic mitoses
Houston, J.; Ohta, M.; Gomez-Cavazos, J. S.; Deep, A.; Corbett, K. D.; Oegema, K.; Lara-Gonzalez, P.; Kim, T.; Desai, A.
10.1101/2022.10.07.511323 — cell biology — Posted on 2022-10-07
3263 Nef enhances HIV-1 replication and infectivity independently of SERINC3 and SERINC5 in CEM T cells
Ramirez, P. W.; Vollbrecht, T.; Acosta, F. M.; Suarez, M.; Angerstein, A. A.; Wallace, J.; O'Connell, R. M.; Guatelli, J.
10.1101/2020.07.15.205757 — microbiology — Posted on 2022-10-07
3265 Chemoproteomics-guided Development of SLC15A4 Inhibitors with Anti-inflammatory Activity
Lazar, D. C.; Wang, W. W.; Chiu, T.-Y.; Li, W.; Jadhav, A. M.; Wozniak, J. M.; Gazaniga, N.; Teijaro, J.; Parker, C. G.
10.1101/2022.10.07.511216 — immunology — Posted on 2022-10-07
3266 Feedback-based motor control can guide plasticity and drive rapid learning
Feulner, B.; Perich, M. G.; Miller, L. E.; Clopath, C.; Gallego, J. A.
10.1101/2022.10.06.511108 — neuroscience — Posted on 2022-10-07
3268 Escalation of alcohol intake is associated with regionally decreased insular cortex activity but not associated with changes in taste quality
Mukherjee, A.; Paladino, M. S.; McSain, S. L.; Gilles-Thomas, E. A.; Lichte, D. D.; Camadine, R. D.; Willock, S.; Sontate, K.; Honeycutt, S. C.; Loney, G. C.
10.1101/2022.10.06.511140 — neuroscience — Posted on 2022-10-07
3269 Chemico-genetic Analysis of Native Autism Proteomes Reveals Shared Biology Predictive of Functional Modifiers
Gao, Y.; Trn, M.; Shonai, D.; Zhao, J.; Soderblom, E. J.; Garcia-moreno, S. A.; Gersbach, C. A.; Wetsel, W. C.; Dawson, G.; Velmeshev, D.; Jiang, Y.-h.; Sloofman, L.; Buxbaum, J.; Soderling, S. H.
10.1101/2022.10.06.511211 — neuroscience — Posted on 2022-10-07
3273 Nicotine enhances intravenous self-administration of cannabinoids in adult rats
Stringfield, S. J.; Sanders, B. E.; Suppo, J. A.; Sved, A. F.; Torregrossa, M. M.
10.1101/2022.10.06.510908 — neuroscience — Posted on 2022-10-07
3277 GLUT1 ablation in astrocytes paradoxically improves central and peripheral glucose metabolism via enhanced insulin-stimulated ATP release
Ardanaz, C. G.; De la Cruz, A.; Elizalde-Horcada, M.; Puerta, E.; Ramirez, M. J.; Ortega, J. E.; Urbiola, A.; Ederra, C.; Ariz, M.; Ortiz-de-Solorzano, C.; Fernandez-Irigoyen, J.; Santamaria, E.; Karsenty, G.; Bruning, J. C.; Solas, M.
10.1101/2022.10.06.511112 — neuroscience — Posted on 2022-10-07
3278 Multi range ERK responses shape the proliferative trajectory of single cells following oncogene induced senescence
Chen, J.-Y.; Hug, C.; Reyes, J.; Tian, C.; Gerosa, L.; Fröhlich, F.; Ponsioen, B.; Snippert, H. J. G.; Spencer, S. L.; Jambhekar, A.; Sorger, P. K.; Lahav, G.
10.1101/2022.10.06.511142 — systems biology — Posted on 2022-10-07
3279 Neuronal E93 regulates metabolic homeostasis
Yip, C.; Wyler, S.; Yamazaki, S.; Rothenfluh, A.; Lee, S.; YOU, Y.-J.; Elmquist, J.
10.1101/2022.10.06.511196 — physiology — Posted on 2022-10-07
3280 Larval density in the invasive Drosophila suzukii: immediate and delayed effects on life-history traits
Reyes-Ramirez, A.; Belgaidi, Z.; Gibert, P.; Pommier, T.; Siberchicot, A.; Mouton, L.; Desouhant, E.
10.1101/2022.10.06.511120 — ecology — Posted on 2022-10-07
3282 The lectin receptor Clec4F participates in the capture of circulating parasite mucins by Kupffer cells in cystic echinococcosis.
Barrios, A. A.; Mouhape, C.; Schreiber, L.; Nell, J.; Suarez-Martins, M.; Schlapp, G.; Meikle, M. N.; Mulet, A. P.; Hsu, T.-L.; Hsieh, S.-L.; Mourglia-Ettlin, G.; Gonzalez, C.; Crispo, M.; Barth, T. F. E.; Casaravilla, C.; Jenkins, S. J.; Diaz, A.
10.1101/2022.10.06.511139 — immunology — Posted on 2022-10-07
3284 The striatum drives the ergogenic effects of caffeine
Alves, A. C. d. B.; Speck, A. E.; Farias, H. R.; dos Santos, N. S.; Pannata, G. d. S.; Tavares, A. P.; Martins, L. M.; de Oliveira, J.; Tome, A. R.; Cunha, R.; Aguiar, A. S.
10.1101/2022.10.06.511163 — neuroscience — Posted on 2022-10-07
3289 A SI3-sigma; arch stabilizes cyanobacteria transcription initiation complex
Shen, L.; Lai, G.; You, L.; Shi, J.; Wu, X.; Puiu, M.; Gu, Z.; Feng, Y.; Yuzenkova, Y.; Zhang, Y.
10.1101/2022.10.06.511230 — biochemistry — Posted on 2022-10-07
3290 The X-factor in ART: does the use of Assisted Reproductive Technologies influence DNA methylation on the X chromosome?
Romanowska, J.; Nustad, H. E.; Page, C. M.; Denault, W. R. P.; Bohlin, J.; Lee, Y.; Magnus, M. C.; Haftorn, K. L.; Gjerdevik, M.; Novakovic, B.; Saffery, R.; Gjessing, H. K.; Lyle, R.; Magnus, P. M.; Haberg, S. E.; Jugessur, A.
10.1101/2022.10.06.510603 — genetics — Posted on 2022-10-07
3296 Cellular sources and targets of type I interferons that drive susceptibility to tuberculosis
Kotov, D. I.; Lee, O. V.; Langner, C.; Guillen, J. V.; Peters, J. M.; Moon, A.; Burd, E. M.; Witt, K. C.; Stetson, D. B.; Jaye, D. L.; Bryson, B. D.; Vance, R. E.
10.1101/2022.10.06.511233 — immunology — Posted on 2022-10-07
3298 A ternary neural code resolves error and sharpening signals
Naud, R.; Wang, X.; Friedenberger, Z.; Shin, J. N.; Beique, J.-C.; Larkum, M.; Doron, G.
10.1101/2022.10.07.511138 — neuroscience — Posted on 2022-10-07
3299 Nonuniform structural properties of wings confer sensing advantages
Weber, A. I.; Babaei, M.; Mamo, A.; Brunton, B. W.; Daniel, T. L.; Bergbreiter, S.
10.1101/2022.10.04.510910 — neuroscience — Posted on 2022-10-07
3300 Triac treatment prevents neurodevelopmental and locomotor impairments in Mct8/Oatp1c1 double knockout mice.
Chen, J.; Salveridou, E.; Liebmann, L.; Sundaram, S. M.; Doycheva, D.; Markova, B.; Huebner, C. A.; Boelen, A.; Visser, W. E.; Heuer, H.; Mayerl, S.
10.1101/2022.10.07.511125 — neuroscience — Posted on 2022-10-07
3303 Indigenous Cultural Safety Training for Applied Health, Social Work and Education Professionals: A PRISMA Scoping Review
MacLean, T. L.; Qiang, J.; Henderson, L.; Andrea, B.; Howard, L.; Pringle, V.; Tanzin, B.; Rice, E.; Di Ruggiero, E.; Mashford-Pringle, A.
10.1101/2022.10.06.511097 — scientific communication and education — Posted on 2022-10-07
3304 Ketone body metabolism declines with age in mice in a sex-dependent manner
Eap, B.; Nomura, M.; Panda, O.; Garcia, T. Y.; King, C. D.; Rose, J. P.; Leone, T. C.; Kelly, D. P.; Schilling, B.; Newman, J. C.
10.1101/2022.10.05.511032 — physiology — Posted on 2022-10-07
3307 Reactive fungal insoles
Nikolaidou, A.; Phllips, N.; Tsompanas, M.-A.; Adamatzky, A.
10.1101/2022.10.06.511010 — biophysics — Posted on 2022-10-07
3313 Chromosome-scale genome assembly of the pink bollworm, Pectinophora gossypiella, a global pest of cotton
Stahlke, A. R.; Chang, J.; Chudalayandi, S.; Heu, C. C.; Geib, S. M.; Scheffler, B. E.; Childers, A. K.; Fabrick, J. A.
10.1101/2022.10.07.511331 — genomics — Posted on 2022-10-07
3314 Direct estimation of genome mutation rates from pedigrees in free-ranging baleen whales
Suarez-Menendez, M.; Berube, M.; Furni, F.; Rivera-Leon, V. E.; Heide-Jorgensen, M.-P.; Larsen, F.; Sears, R.; Ramp, C.; Eriksson, B. K.; Etienne, R. S.; Robbins, J.; Palsboll, P. J.
10.1101/2022.10.06.510775 — genetics — Posted on 2022-10-07
3317 CBD resistant Salmonella strains are susceptible to Epsilon 34 phage tailspike protein
Ibrahim, I.; Ayariga, J. A.; Xu, J.; Adebanjo, A.; Samuel-Foo, M.; Ajayi, O. S.
10.1101/2022.10.06.511232 — microbiology — Posted on 2022-10-07
3319 GESIAP: A Versatile Genetically Encoded Sensor-based Image Analysis Program
Zheng, W. S.; Zhang, Y.; Zhu, R. E.; Zhang, P.; Gupta, S.; Huang, L.; Sahoo, D.; Guo, K.; Glover, M. E.; Vadodaria, K. C.; Li, M.; Qian, T.; Jing, M.; Feng, J.; Wan, J.; Borden, P. M.; Podgorski, K.; Ali, F.; Kwan, A. C.; Gan, L.; Lin, L.; Gage, F. H.; Venton, B. J.; Marvin, J. S.; Clinton, S. M.; Zhang, M.; Looger, L.; Li, Y.; Zhu, J. J.
10.1101/2022.10.05.511006 — neuroscience — Posted on 2022-10-07
3320 Spatiotemporal orchestration of multicellular transcriptional programs and communications in spinal cord injury
Wang, Z.; Li, Z.; Luan, T.; Cui, G.; Shu, S.; Liang, Y.; Zhang, K.; Yu, W.; Cui, J.; Li, A.; Peng, G.; Fang, Y.
10.1101/2022.10.07.511269 — neuroscience — Posted on 2022-10-07
3323 Losses resulting from deliberate exploration trigger beta oscillations in frontal cortex
Chernyshev, B. V.; Pultsina, K. I.; Tretyakova, V. D.; Miasnikova, A. S.; Prokofyev, A. O.; Kozunova, G. L.; Stroganova, T. A.
10.1101/2022.10.06.510948 — neuroscience — Posted on 2022-10-07
3324 Integrative Multi-Omics Approaches for Identifying Cervical Cancer Therapeutic Targets
Duppala, S. K.; Yadala, R.; Velingkar, A.; Suravajhala, P.; Pawar, S.; Vuree, S.
10.1101/2022.10.07.511244 — systems biology — Posted on 2022-10-07
3327 Unified and standardized mass spectrometry data processing in Python using spectrum_utils
Bittremieux, W.; Levitsky, L. I.; Pilz, M.; Sachsenberg, T.; Wang, M.; Dorrestein, P. C.
10.1101/2022.10.04.510894 — bioinformatics — Posted on 2022-10-07
3332 Low-cost and highly efficient: A method for high-quality nucleic acid isolation from cotton fibres
Ahmad, M.; Sarwar, M. B. B.; Ashfaq, R.; Ahmad, A.; Yanag, X.; ud Din, S.; Sajid, M.; Syed, Q.; Abidi, S. H.; Wang, X.
10.1101/2022.10.07.511236 — genomics — Posted on 2022-10-07
3333 The Human Pangenome's sequence conservation reveals a landscape of polymorphic structural variation
Lee, H.; Greer, S. U.; Pavlichin, D. S.; Hughes, C.; Zhou, B.; Weissman, T.; Ji, H. P.
10.1101/2022.10.06.511239 — genomics — Posted on 2022-10-07
3335 An advanced sequence clustering and designation workflow reveals the enzootic maintenance of a dominant West Nile virus subclade in Germany
Santos, P. D.; Gunther, A.; Keller, M.; Homeier-Bachmann, T.; Groschup, M. H.; Beer, M.; Höper, D.; Ziegler, U.
10.1101/2022.10.05.509209 — genetics — Posted on 2022-10-07
3339 Triangulation reduces the polygon of error for the history of Transeurasian
Robbeets, M.; Hudson, M.; Ning, C.; Bouckaert, R.; Savelyev, A.; Kim, G.; Li, T.; Oskolskaya, S.; Gruntov, I.; Mazo, O.; Rhee, S.; Ahn, K.-D.; Fernandes, R.; Shinoda, K.-i.; Kanzawa-Kiriyama, H.; Bjorn, R.; Deng, B.; An, D.-i.; Bentley, J.; Kawashima, T.; Dolinska, J.
10.1101/2022.10.05.510045 — evolutionary biology — Posted on 2022-10-07
3340 Genetic diversity and structure in wild Robusta coffee (Coffea canephora A. Froehner) populations in Yangambi (DR Congo) and their relation with forest disturbance
Depecker, J.; Verleysen, L.; Asimonyio, J.; Hatangi, Y.; Kambale, J.-L.; Mwanga Mwanga, I.; Tshimi, E.; Dhed'a, B.; Bawin, Y.; Staelens, A.; Stoffelen, P.; Ruttink, T.; Vandelook, F.; Honnay, O.
10.1101/2022.10.07.511267 — ecology — Posted on 2022-10-07
3341 Diversity-stability relationships become decoupled across spatial scales: a synthesis of organism and ecosystem types
Wisnoski, N. I.; Andrade, R.; Castorani, M. C. N.; Catano, C. P.; Compagnoni, A.; Lamy, T.; Lany, N. K.; Marazzi, L.; Record, S.; Smith, A. C.; Swan, C. M.; Tonkin, J. D.; Voelker, N. M.; Zarnetske, P. L.; Sokol, E. R.
10.1101/2022.10.04.510879 — ecology — Posted on 2022-10-07
3342 Guitarfishes are plucked: undermanaged in global fisheries despite declining populations and high volume of unreported international trade
Sherman, C. S.; Simpfendorfer, C. A.; Haque, A. B.; Digel, E. D.; Zubick, P.; Eged, J.; Matsushiba, J. H.; Sant, G.; Dulvy, N. K.
10.1101/2022.10.05.510982 — ecology — Posted on 2022-10-07
3343 Local and regional scale mycorrhizal network assembly in an experimental prairie-pasture system
Shek, K. L.; Dawson, H. R.; Maxwell, T.; Bomfim, B.; Reed, P. B.; Bridgham, S.; Bohannan, B.; Silva, L. C. R.
10.1101/2022.10.05.510876 — ecology — Posted on 2022-10-07
3346 Integrated transcriptome and proteome analysis in human brain organoids reveals translational regulation of ribosomal proteins.
Sidhaye, J.; Trepte, P.; Sepke, N.; Novatchkova, M.; Schutzbier, M.; Duernberger, G.; Mechtler, K.; Knoblich, J. A.
10.1101/2022.10.07.511280 — developmental biology — Posted on 2022-10-07
3347 A multiparametric anti-aging CRISPR screen uncovers a role for BAF in protein translation
Breusegem, S. Y.; Houghton, J.; Romero-Bueno, R.; Fragoso-Luna, A.; Kentistou, K. A.; Janssen, A. F. J.; Bright, N. A.; Riedel, C. G.; Perry, J. R. B.; Askjaer, P.; Larrieu, D.
10.1101/2022.10.07.509469 — molecular biology — Posted on 2022-10-07
3348 Communication between the nucleus and the mitochondria via NDUFS4 alternative splicing in gastric cancer cells
Papadaki, V.; Erpapazoglou, Z.; Kokkori, M.; Rogalska, M.; Tsakiri, E.; Ashktorab, H.; Smoot, D. T.; Papanikolopoulou, K.; Samiotaki, M.; Kafasla, P.
10.1101/2022.10.07.511259 — molecular biology — Posted on 2022-10-07
3349 Structure of the two-component S-layer of the archaeon Sulfolobus acidocaldarius
Gambelli, L.; McLaren, M.; Conners, R.; Sanders, K.; Gaines, M. C.; Clark, L.; Gold, V.; Kattnig, D.; Sikora, M.; Hanus, C.; Isupov, M. N.; Daum, B.
10.1101/2022.10.07.511299 — microbiology — Posted on 2022-10-07
3351 Brevicidine, a bacterial non-ribosomally produced cyclic antimicrobial lipopeptide with a unique modus operandi
Zhao, X.; Zhong, X.; Wan, H.; Liu, L.; Song, X.; Zou, Y.; Li, L.; Jia, R.; Lin, J.; Tang, H.; Zhao, S.; Lang, Y.; Yin, Z.; Kuipers, O. P.
10.1101/2022.10.07.511251 — microbiology — Posted on 2022-10-07
3352 Single-cell analysis of myeloid cells in HPV+ tonsillar cancer
Gomez Jimenez, D.; Altunbulakli, C.; Swoboda, S.; Sobti, A.; Ali, A.; Askmyr, D.; Lindstedt, M.
10.1101/2022.10.04.510291 — immunology — Posted on 2022-10-07
3354 MHC class Ia molecules facilitate MCK2-dependent MCMV infection of macrophages and virus dissemination to the salivary gland
Bosnjak, B.; Henze, E.; Lueder, Y.; Do, K. T. H.; Rezalofti, A.; Ritter, C.; Schimrock, A.; Willenzon, S.; Georgiev, H.; Fritz, L.; Galla, M.; Wagner, K.; Messerle, M.; Foerster, R.
10.1101/2022.10.05.510922 — immunology — Posted on 2022-10-07
3356 The vertical position of visual information conditions spatial memory performance in healthy aging
Durteste, M.; Van Poucke, L.; Combariza, S.; Benziane, B. A.; Sahel, J.-A.; Ramanoël, S.; Arleo, A.
10.1101/2022.10.05.510774 — neuroscience — Posted on 2022-10-07
3359 Patterns of Ongoing Thought in the Real-World
Mulholland, B.; Goodall-Halliwell, I.; Wallace, R.; Chitiz, L.; Mckeown, B.; Rastan, A.; Poerio, G.; Leech, R.; Turnbull, A.; Klein, A.; Van Auken, W.; Milham, M.; Wammes, J.; Jefferies, E.; Smallwood, J.
10.1101/2022.10.05.510994 — neuroscience — Posted on 2022-10-07
3365 Perioral secretions enable complex social signaling in African mole-rats (genus Fukomys)
Caspar, K. R.; Stopka, P.; Issel, D.; Katschak, K. H.; Zoellner, T.; Zupanc, S.; Zacek, P.; Begall, S.
10.1101/2022.10.04.510857 — zoology — Posted on 2022-10-07
3369 Generative Modeling of Single Cell Gene Expression for Dose-Dependent Chemical Perturbations
Kana, O. Z.; Nault, R. Z.; Filipovic, D.; Marri, D. K.; Zacharewski, T.; Bhattacharya, S.
10.1101/2022.10.05.510890 — bioinformatics — Posted on 2022-10-07
3374 Multiscale model of the different modes of cancer cell invasion
Ruscone, M.; Montagud, A.; Chavrier, P.; Destaing, O.; Zinovyev, A.; Barillot, E.; Noel, V.; Calzone, L.
10.1101/2022.10.07.511296 — bioinformatics — Posted on 2022-10-07
3375 Engineering human spinal microphysiological systems to model opioid-induced tolerance
Cai, H.; Ao, Z.; Tian, C.; Wu, Z.; Kaurich, C.; Chen, Z.; Gu, M.; Hohmann, A. G.; Mackie, K.; Guo, F.
10.1101/2022.10.03.510710 — bioengineering — Posted on 2022-10-07
3378 Multiplex HDR for Disease and Correction Modeling of SCID by CRISPR Genome Editing in Human HSPCs
Iancu, O.; Allen, D.; Knop, O.; Zehavi, Y.; Breier, D.; Arbiv, A.; Lev, A.; Lee, Y. N.; Beider, K.; Nagler, A.; Somech, R.; Hendel, A.
10.1101/2022.10.07.511272 — bioengineering — Posted on 2022-10-07
3381 The first complete mitochondrial genome of Diadema antillarum (Diadematoida, Diadematidae)
Majeske, A.; Mercado Capote, A. J.; Komissarov, A.; Bogdanova, A.; Schizas, N.; Castro Marquez, S. O.; Hilkert, K.; Wolfsberger, W.; Oleksyk, T. K.
10.1101/2022.10.05.510842 — genomics — Posted on 2022-10-07
3385 A semi-automatic workflow to process camera trap images in R
Böhner, H.; Kleiven, E. F.; Ims, R. A.; Soininen, E. M.
10.1101/2022.10.05.510927 — ecology — Posted on 2022-10-07
3387 Predicting Pacific cod spawning habitat in a changing climate
Bigman, J. S.; Laurel, B. J.; Kearney, K.; Hermann, A. J.; Cheng, W.; Holsman, K. K.; Rogers, L. A.
10.1101/2022.10.04.510851 — ecology — Posted on 2022-10-07
3388 Distinct Heterogeneity in the Naive T cell Compartments of Children and Adults
Gustafson, C. E.; Thomson, Z.; He, Z.; Swanson, E.; Henderson, K.; Pebworth, M.-P. L.; Okada, L. Y.; Heubeck, A. T.; Roll, C. R.; Hernandez, V.; Weiss, M. D.; Genge, P. C.; Reading, J.; Giles, J. R.; Manne, S.; Dougherty, J.; Jasen, C.; Greenplate, A. R.; Becker, L. A.; Graybuck, L. T.; Vasaikar, S. V.; Szeto, G. L.; Savage, A. K.; Speake, C.; Buckner, J. H.; Li, X.-j.; Torgerson, T. R.; Wherry, E. J.; Bumol, T. F.; Vella, L. A.; Henrickson, S. H.; Skene, P. J.
10.1101/2022.10.04.510869 — immunology — Posted on 2022-10-07
3390 Upregulation of CD55 complement regulator in distinct PBMC subpopulations of COVID-19 patients is associated with suppression of interferon responses.
Detsika, M. G.; Sakkou, M.; Triantafyllidou, V.; Konstantopoulos, D.; Grigoriou, E.; Psarra, K.; Jahaj, E.; Dimpoulou, I.; Orfanos, S. E.; Tsirogianni, A.; Kollias, G.; Kotanidou, A.
10.1101/2022.10.07.510750 — immunology — Posted on 2022-10-07
3391 Eradication of tumors with pre-existing antigenic heterogeneity by vaccine-mediated co-engagement of CAR T and endogenous T-cells
Ma, L.; Morgan, D. M.; Sulkaj, I.; Yousefpour, P.; Whittaker, C. A.; Abraham, W.; Li, N.; Love, J. C.; Irvine, D. J.
10.1101/2022.10.05.511036 — immunology — Posted on 2022-10-07
3392 GBP2 aggregates LPS and activates the caspase-4 inflammasome independent of the bacterial encapsulation factor GBP1
Dickinson, M. S.; Kutsch, M.; Sistemich, L.; Hernandez, D.; Needham, D.; lesser, c.; Herrmann, C.; Coers, J.
10.1101/2022.10.05.511023 — immunology — Posted on 2022-10-07
3393 Umbilical cord blood-derived cell therapy for perinatal brain injury: A systematic review & meta-analysis of preclinical studies - Part A
Nguyen, T.; Purcell, E.; Smith, M.; Penny, T.; Paton, M.; Zhou, L.; Jenkin, G.; Miller, S.; McDonald, C.; Malhotra, A.
10.1101/2022.10.05.510916 — neuroscience — Posted on 2022-10-07
3395 Serotonergic Modulation of Spinal Circuitry Restores Motor Function after Chronic Spinal Cord Injury
Walvekar, S.; Robinson, R. B.; Chadwick, H. M.; Burch, R. M.; Ding, H.; Perlmutter, S. I.; Moorjani, S.
10.1101/2022.10.04.510858 — neuroscience — Posted on 2022-10-07
3399 Whole brain evaluation of cortical micro-connectomes.
Matsuda, K.; Nakajima, R.; Shirakami, A.; Akutsu, T.; Shimono, M.
10.1101/2022.10.05.510240 — neuroscience — Posted on 2022-10-07
3402 Non-Gaussian Normative Modelling With Hierarchical Bayesian Regression
de Boer, A. A. A.; Kia, S. M.; Rutherford, S.; Zabihi, M.; Fraza, C.; Barkema, P.; Westlye, L. T.; Andreassen, O.; Hinne, M.; Beckmann, C. F.; Marquand, A. F.
10.1101/2022.10.05.510988 — neuroscience — Posted on 2022-10-07
3403 Integrity of the minor spliceosome in the developing mouse hypothalamus determines neuronal subtype composition regulating energy balance.
White, A. K.; Drake, K. D.; Porczak, A. E.; Tirado-Mansilla, G.; Lee, M. F.; Hyatt, K. C.; Chow, C.; DeQuattro, T.; Mickelsen, L. E.; Sciolino, N. R.; Jackson, A. C.; Kanadia, R. N.
10.1101/2022.10.04.510883 — neuroscience — Posted on 2022-10-07
3404 Sexually dimorphic neural encoding of threat discrimination in nucleus accumbens afferents drives suppression of reward behavior
Muir, J.; Tse, Y. C.; Iyer, E.; Sorensen, J.; Eid, R. S.; Cvetkovska, V.; Wassef, K.; Gostlin, S.; Spencer, N. J.; Bagot, R. C.
10.1101/2022.10.04.510865 — neuroscience — Posted on 2022-10-07
3405 Rapid ex vivo reverse genetics identifies the essential determinants of prion protein toxicity
Reimann, R. R.; Puzio, M.; Rosati, A.; Emmenegger, M.; Schneider, B. L.; Valdes, P.; Huang, D.; Caflisch, A.; Aguzzi, A.
10.1101/2022.10.05.509883 — neuroscience — Posted on 2022-10-07
3406 WWOX P47T loss-of-function mutation induces epilepsy, progressive neuroinflammation, and cerebellar degeneration in mice phenocopying human SCAR12
Hussain, T.; Sanchez, K.; Crayton, J.; Saha, D.; Jeter, C.; Lu, Y.; Abba, M.; Seo, R.; Noebels, J. L.; Fonken, L.; Aldaz, C. M.
10.1101/2022.10.05.510979 — neuroscience — Posted on 2022-10-07
3407 A Synthetic ERRα Agonist Induces an Acute AerobicExercise Response and Enhances Exercise Capacity
Billon, C.; Banerjee, S.; Situala, S.; Welch, R.; Hegazy, L.; Elgendy, B.; Oh, T. G.; Kazantzis, M.; Chatterjee, A.; Chrivia, J.; Hayes, M.; Xu, W.; Hamilton, A.; Huss, J.; Zhang, L.; Walker, J. K.; Downes, M.; Evans, R.; Burris, T.
10.1101/2022.10.05.510974 — pharmacology and toxicology — Posted on 2022-10-07
3408 Scalable early detection of grapevine virus infection with airborne imaging spectroscopy
Romero Galvan, F. E.; Sousa, D.; Pavlick, R.; Aggarwal, S.; Trolley, G. R.; Forrestel, E. J.; Bolton, S. L.; Dokoozlian, N.; Alsina, M. D. M.; Gold, K. M.
10.1101/2022.10.04.510827 — pathology — Posted on 2022-10-07
3409 Surface glia predominantly contribute to the development of ALS/FTD in Drosophila model
Snow, B. A.; Stevenson, C. C.; Kaur, J.; Lee, S. G.; Wei, Y.; Miao, H.; Kim, W. J.
10.1101/2022.10.07.511246 — pathology — Posted on 2022-10-07
3410 Activin A promotes bone fracture repair and acts through a novel myofibroblastic cell population in callus
Yao, L.; Zhong, L.; Wei, Y.; Gui, T.; Wang, L.; Ahn, J.; Boerckel, J. D.; Rux, D.; Mundy, C.; Qin, L.; Pacifici, M.
10.1101/2022.10.05.510962 — pathology — Posted on 2022-10-07
3411 Iron Chelation Improves Ineffective Erythropoiesis and Iron Overload in Myelodysplastic Syndrome Mice
An, W.; Feola, M.; Aluri, S.; Ruiz-Martinez, M.; Sridharan, A.; Levy, M.; Fibach, E.; Zhu, X.; Verma, A. K.; Ginzburg, Y.
10.1101/2022.10.05.510967 — pathology — Posted on 2022-10-07
3412 A Suite of Advanced Tutorials for the WESTPA 2.0 Rare-Events Sampling Software
Bogetti, A.; Leung, J.; Russo, J.; Zhang, S.; Thompson, J.; Saglam, A.; Ray, D.; Abraham, R.; Faeder, J.; Andricioaei, I.; Adelman, J.; Zwier, M.; LeBard, D.; Zuckerman, D. M.; Chong, L.
10.1101/2022.10.04.510803 — biophysics — Posted on 2022-10-07
3413 Combining molecular and cell painting image data for mechanism of action prediction
Tian, G.; Harrison, P. J.; Sreenivasan, A. P.; Carreras Puigvert, J.; Spjuth, O.
10.1101/2022.10.04.510834 — bioinformatics — Posted on 2022-10-07
3414 EMPIAR: The Electron Microscopy Public Image Archive
Iudin, A.; Korir, P. K.; Somasundharam, S.; Weyand, S.; Cattavitello, C.; Fonseca, N.; Salih, O.; Kleywegt, G. J.; Patwardhan, A.
10.1101/2022.10.04.510785 — bioinformatics — Posted on 2022-10-07
3421 Mechanical Stimuli such as Shear Stress and Piezo1 Stimulation Generate Red Blood Cell Extracellular Vesicles
Sangha, G. S.; Weber, C. M.; Sapp, R. M.; Setua, S.; Thangaraju, K.; Pettebone, M.; Doctor, A.; Buehler, P. W.; Clyne, A. M.
10.1101/2022.10.04.510887 — bioengineering — Posted on 2022-10-07
3425 Zebrafish screen of high-confidence targets at insomnia GWAS loci implicates MEIS1, SKIV2L, and ARFGAP2 as conserved regulators of sleep-wake behaviors
Zimmerman, A. J.; Doldur-Balli, F.; Keenan, B. T.; Shetty, Z. Y.; Palermo, J.; Chesi, A.; Sonti, S.; Pahl, M. C.; Brown, E. B.; Pippin, J. A.; Wells, A. D.; Mazzotti, D. R.; Veatch, O. J.; Krishnan, A.; Gehrman, P. R.; Keene, A. C.; Grant, S. F. A.; Pack, A. I.
10.1101/2022.10.05.511011 — genetics — Posted on 2022-10-07
3426 Simple scaling laws control the genetic architectures of human complex traits
Simons, Y. B.; Mostafavi, H.; Smith, C. J.; Pritchard, J. K.; Sella, G.
10.1101/2022.10.04.509926 — genetics — Posted on 2022-10-07
3430 Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.
Mihalic, F.; Benz, C.; Kassa, E.; Lindqvist, R.; Simonetti, L.; Inturi, R.; Aronsson, H.; Andersson, E.; Chi, C. N.; Davey, N. E.; Overby, A. K.; Jemth, P.; Ivarsson, Y.
10.1101/2022.10.07.511324 — molecular biology — Posted on 2022-10-07
3431 Fate and plasticity of SARS-CoV-2-specific B cells during memory and recall response in humans
Zurbuchen, Y.; Michler, J.; Taeschler, P.; Adamo, S.; Cervia, C.; Raeber, M. E.; Acar, I. E.; Nilsson, J.; Soyka, M. B.; Moor, A. E.; Boyman, O.
10.1101/2022.10.07.511336 — immunology — Posted on 2022-10-07
3432 Baculoviral COVID-19 Delta DNA vaccine cross-protects against SARS-CoV2 variants in K18-ACE2 transgenic mice
Jang, Y.; Cho, H.; Chun, J.; Park, K.; Nowakowska, A.; Kim, J.; Lee, H.; Lee, C.; Han, Y.; Lee, H.-J.; Shin, H.-Y.; Kim, Y. B.
10.1101/2022.10.07.511252 — immunology — Posted on 2022-10-07
3433 Development of SARS-CoV-2 mRNA vaccines encoding spike N-terminal and receptor binding domains
Stewart-Jones, G.; Elbashir, S. M.; Wu, K.; Lee, D.; Renzi, I.; Ying, B.; Koch, M.; Sein, C. E.; Choi, A.; Whitener, B.; Garcia-Dominguez, D.; Henry, C.; Woods, A.; Ma, L.; Montes Berrueta, D.; Avena, L. E.; Quinones, J.; Falcone, S.; Hsiao, C. J.; Scheaffer, S. M.; Thackray, L. B.; White, P.; Diamond, M. S.; Edwards, D. K.; Carfi, A.
10.1101/2022.10.07.511319 — immunology — Posted on 2022-10-07
3435 KMT2D regulates thymic egress by modulating maturation and integrin expression
Potter, S. J.; Zhang, L.; Kotliar, M.; Wu, Y.; Schafer, C.; Stefan, K.; Boukas, L.; Qu'd, D.; Bodamer, O.; Simpson, B. N.; Barski, A.; Lindsley, A. W.; Bjornsson, H. T.
10.1101/2022.10.04.510662 — immunology — Posted on 2022-10-07
3436 Does prefrontal connectivity during task switching help or hinder children's performance?
Schwarze, S. A.; Laube, C.; Khosravani, N.; Lindenberger, U.; Bunge, S.; Fandakova, Y.
10.1101/2022.10.04.510761 — neuroscience — Posted on 2022-10-07
3437 Direct comparison of epifluorescence and immunostaining for assessing viral mediated gene expression in the primate brain
Daw, T. B.; El-Nahal, H. G.; Basso, M. A.; Jun, E. J.; Bautista, A. R.; Samulski, R. J.; Sommer, M. A.; Bohlen, M. O.
10.1101/2022.10.04.510807 — neuroscience — Posted on 2022-10-07
3438 Epigenetics of post-operative delirium: A genome-wide DNA methylation study of neurosurgery patients
Yamanashi, T.; Crutchley, K. J.; Wahba, N. E.; Nagao, T.; Marra, P. S.; Akers, C. C.; Sullivan, E. J.; Iwata, M.; Howard, M. A.; Cho, H. R.; Kawasaki, H.; Hughes, C. G.; Pandharipande, P. P.; Hefti, M. M.; Shinozaki, G.
10.1101/2022.10.04.510706 — neuroscience — Posted on 2022-10-07
3439 SBT-272 improves TDP-43 pathology in the ALS motor cortex by modulating mitochondrial integrity, motility, and function
Gautam, M.; Genc, B.; Helmold, B.; Ahrens, A.; Kuka, J.; Makrecka-Kuka, M.; Gunay, A.; Kocak, N.; Aguilar-Wickings, I. R.; Keefe, D.; Zheng, G.; Swaminathan, S.; Redmon, M.; Zariwala, H. A.; Ozdinler, P. H.
10.1101/2022.10.04.510854 — neuroscience — Posted on 2022-10-07
3447 EGIDExpress: An Interactive Shiny Web App to Visualize and Share Large Biological Datasets
Besse, J. A.; Osswald, G. A.; Ballaban, A. Y.; Caldwell, J. M.; Rothenberg, M. E.
10.1101/2022.10.03.510709 — bioinformatics — Posted on 2022-10-07
3448 Seasonal siderophore uptake and biosynthesis associated with carbon flux at Station ALOHA
Bundy, R. M.; Manck, L. E.; Boiteau, R. M.; Park, J.; Delong, E. F.; Hawco, N. J.; Church, M. J.; Saito, M.; Repeta, D. J.
10.1101/2022.10.04.510528 — bioinformatics — Posted on 2022-10-07
3453 Incipient parallel evolution of SARS-CoV-2 Deltacron variant in South Brazil
Sant Anna, F. H.; Andreis, T. F.; Salvato, R. S.; Muterle, A. P.; Comerlato, J.; Gregianini, T. S.; Barcellos, R. B.; Godinho, F. M.; Resende, P. C.; Wallau, G. L.; Castro, T. R.; Casarin, B. C.; Vieira, A. A.; Schwarzbold, A. V.; Trindade, P. A.; Giannini, G. L.; Freese, L.; Bristot, G.; Brasil, C. S.; Rocha, B. O.; Martins, P. B.; Oliveira, F. H.; Oosterhout, C. v.; Wendland, E.
10.1101/2022.10.06.511203 — evolutionary biology — Posted on 2022-10-07
3454 Inferring time of infection from field data using dynamic models of antibody decay
Borremans, B.; Mummah, R. O.; Guglielmino, A. H.; Galloway, R. L.; Hens, N.; Prager, K. C.; Lloyd-Smith, J. O.
10.1101/2022.10.03.510698 — ecology — Posted on 2022-10-07
3460 Convergent evolution of plant pattern recognition receptors sensing cysteine-rich patterns from three microbial kingdoms
Yang, Y.; Steidele, C. E.; Loeffelhardt, B.; Kolb, D. E.; Leisen, T.; Zhang, W.; Ludwig, C.; Felix, G.; Seidl, M. F.; Nuernberger, T.; Hahn, M.; Gust, B.; Gross, H.; Hueckelhoven, R.; Gust, A. A.
10.1101/2022.10.06.511083 — plant biology — Posted on 2022-10-07
3462 Contrasting roles of the wheat MRC in promoting starch granule initiation in leaves and repressing the onset of B-type granule initiation in the endosperm
Chen, J.; Chen, Y.; Watson-Lazowski, A.; Hawkins, E.; Barclay, J. E.; Fahy, B.; Denley-Bowers, R.; Corbin, K.; Warren, F. J.; Blennow, A.; Uauy, C.; Seung, D.
10.1101/2022.10.07.511297 — plant biology — Posted on 2022-10-07
3464 The conserved upstream ORF of the Arabidopsis ANAC082 gene mediates translational upregulation in response to nucleolar stress
Sasaki, S.; Murakami, T.; Yasumuro, M.; Makita, A.; Oi, Y.; Hiragori, Y.; Watanabe, S.; Kudo, R.; Hayashi, N.; Ohbayash, I.; Sugiyama, M.; Yamashita, Y.; Naito, S.; Onouchi, H.
10.1101/2022.10.07.511279 — plant biology — Posted on 2022-10-07
3466 Natural variation in Arabidopsis responses to Plasmodiophora brassicae reveals an essential role for RPB1
Ochoa, J. C.; Mukhopadhyay, S.; Bieluszewski, T.; Jedryczka, M.; Malinowski, R.; Truman, W.
10.1101/2022.10.06.511079 — plant biology — Posted on 2022-10-07
3467 The FIGNL1-interacting protein C1orf112 is synthetic lethal with PICH and mediates RAD51 retention on chromatin.
Stok, C.; van den Tempel, N.; Everts, M.; Wierenga, E.; Bakker, F.; Kok, Y.; Teles Alves, I.; Jae, L.; Bhattacharya, A.; Karanika, E.; Perepelkina, P.; Bergink, S.; Chan, K.-L.; de Boer, R.; Fehrmann, R.; van Vugt, M.
10.1101/2022.10.07.511242 — cancer biology — Posted on 2022-10-07
3469 UGDH promotes tumor-initiating cells and a fibroinflammatory tumor microenvironment in ovarian cancer.
Harrington, B. S.; Kamdar, R. D.; Korrapati, S.; Caminear, M. W.; Ning, F.; Hernandez, L. F.; Butcher, D.; Edmondson, E.; Traficante, N.; Gough, M.; Rogers, R.; Lourie, R.; Shetty, J.; Tran, B.; Elloumi, F.; Abdelmaksoud, A.; Lal Nag, M.; Mazan-Mamczarz, K.; House, C. D.; Hooper, J. D.; Annunziata, C. M.
10.1101/2022.10.07.509566 — cancer biology — Posted on 2022-10-07
3471 Welcome to the big leaves: best practices for improving genome annotation in non-model plant genomes
Vuruputoor, V. S.; Monyak, D.; Fetter, K. C.; Webster, C.; Zaman, S.; Bhattarai, A.; Bennett, J.; McEvoy, S.; Shrestha, B.; Caballero, M.; Wegrzyn, J.
10.1101/2022.10.03.510643 — bioinformatics — Posted on 2022-10-07
3473 Regulation of the mammalian-brain V-ATPase via ultra-slow mode-switching
KOSMIDIS, E.; Shuttle, C. G.; Preobraschenski, J.; Ganzella, M.; Johnson, P. J.; Veshaguri, S.; Moeller, M. P.; Marantos, O.; Pedersen, J. L.; Jahn, R.; Stamou, D.
10.1101/2022.10.06.511076 — biophysics — Posted on 2022-10-07
3476 Population Genomics of Stone Age Eurasia
Allentoft, M. E.; Sikora, M.; Refoyo-Martinez, A.; Irving-Pease, E. K.; Fischer, A.; Barrie, W.; Ingason, A.; Stenderup, J.; Sjögren, K.-G.; Pearson, A.; Sousa da Mota, B.; Paulsson, B. S.; Halgren, A. S.; Macleod, R.; Schjellerup Jorkov, M. L.; Demeter, F.; Novosolov, M.; Sorensen, L.; Nielsen, P. O.; Henriksen, R. A.; Vimala, T.; McColl, H.; Margaryan, A.; Ilardo, M.; Vaughn, A.; Mortensen, M. F.; Nielsen, A. B.; Hede, M. U.; Rasmussen, P.; Vinner, L.; Renaud, G.; Stern, A. J.; Trolle Jensen, T. Z.; Johannsen, N. N.; Scorrano, G.; Schroeder, H.; Lysdahl, P.; Ramsoe, A.; Skorobogatov, A.; Sc
10.1101/2022.05.04.490594 — evolutionary biology — Posted on 2022-10-07
3479 PKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy
Yoshida, T.; Latt, K. Z.; Rosenberg, A. Z.; Santo, B. A.; Myakala, K.; Ishimoto, Y.; Zhao, Y.; Shrivastav, S.; Jones, B. A.; Yang, X.; Wang, X.; Tutino, V. M.; Sarder, P.; Levi, M.; Okamoto, K.; Winkler, C. A.; Kopp, J. B.
10.1101/2022.10.03.510678 — pathology — Posted on 2022-10-07
3480 Live Cell Multicolour Lifetime Imaging Using Genetically Encodable Fluorophores
Starling, T.; Carlon-Andres, I.; Iliopoulou, M.; Williamson, D. J.; Padilla-Parra, S.
10.1101/2022.10.06.511114 — biophysics — Posted on 2022-10-07
3483 Talin and kindlin cooperate to control the density of integrin clusters.
Pernier, J.; Cardoso Dos Santos, M.; Souissi, M.; Joly, A.; Narassimprakash, H.; Rossier, O.; Giannone, G.; Helfer, E.; Sengupta, K.; Le Clainche, C.
10.1101/2022.10.07.511266 — biochemistry — Posted on 2022-10-07
3485 The Selection Landscape and Genetic Legacy of Ancient Eurasians
Irving-Pease, E. K.; Refoyo-Martinez, A.; Ingason, A.; Pearson, A.; Fischer, A.; Barrie, W.; Sjögren, K.-G.; Halgren, A. S.; Macleod, R.; Demeter, F.; Henriksen, R. A.; Vimala, T.; McColl, H.; Vaughn, A.; Speidel, L.; Stern, A. J.; Scorrano, G.; Ramsoe, A.; Schork, A. J.; Rosengren, A.; Zhao, L.; Kristiansen, K.; Sudmant, P. H.; Lawson, D. J.; Durbin, R.; Korneliussen, T.; Werge, T.; Allentoft, M. E.; Sikora, M.; Nielsen, R.; Racimo, F.; Willerslev, E.
10.1101/2022.09.22.509027 — evolutionary biology — Posted on 2022-10-07
3489 Farnesoid X Receptor suppresses lipid peroxidation and ferroptosis
Tschuck, J.; Theilacker, L.; Rothenaigner, I.; Weiss, S. A.; Akdogan, B.; Mueller, C.; Graf, R.; Brandner, S.; Puetz, C.; Rieder, T.; Schmitt-Kopplin, P.; Zischka, H.; Schorpp, K.; Hadian, K.
10.1101/2022.10.07.511245 — cell biology — Posted on 2022-10-07
3490 A 3D bioprintable hydrogel with tuneable stiffness for exploring cells encapsulated in matrices of differing stiffnesses
Du, E. Y.; Jung, M.; Skhinas, J.; Tolentino, M. K.; Jamshidi, N.; Houng, J.; Tjandra, K. C.; Engel, M.; Utama, R.; Tilley, R.; Kavallaris, M.; Gooding, J. J.
10.1101/2022.10.06.511222 — cell biology — Posted on 2022-10-07
3491 Stromal STAT5-mediated trophic activity regulates hematopoietic multipotent progenitor niche factors
Wang, Z.; Emmel, G.; Lim, H. S.; Zhu, W.; Kosters, A.; Ghosn, E.; Qiu, P.; Bunting, K.
10.1101/2022.10.07.511255 — cell biology — Posted on 2022-10-07
3492 The voltage-gated sodium channel NaV1.7 underlies endometriosis-associated chronic pelvic pain
Castro, J.; Maddern, J.; Chow, C. Y.; Tran, P.; Vetter, I.; King, G. F.; Brierley, S. M.
10.1101/2022.10.06.511228 — cell biology — Posted on 2022-10-07
3493 Polycomb Repressive Complex 1 subunit Cbx4 positively regulates effector responses in CD8 T cells
Melo, G. A.; Xu, T.; Caloba, C.; Schutte, A. W.; Brum, G.; Passos, T. O.; Higa, L.; Goncalves, A. N. A.; Tanuri, A.; Viola, J. P. B.; Werneck, M. B. F.; Nakaya, H.; Pipkin, M. E.; Martinez, G. J.; Pereira, R. M.
10.1101/2022.10.03.510675 — immunology — Posted on 2022-10-07
3494 Absence of microbiome in chronic infections impairs viral control without affecting CD8 T cell function
Kuhlmann, M.; Kolland, D. D. C.; Almeida, G. P. d.; Hoffmann, C.; von Hoesslin, M.; Berner, J.; Wurmser, C.; Ohnmacht, C.; Zehn, D.
10.1101/2022.10.03.510696 — immunology — Posted on 2022-10-07
3495 Enhanced STAT5a activation rewires exhausted CD8 T cells during chronic stimulation to acquire a hybrid durable effector like state
Beltra, J. C.; Abdel-Hakeem, M. S.; Manne, S.; Zhang, Z.; Huang, H.; Kurachi, M.; Su, L.; Picton, L.; Muroyama, Y.; Casella, V.; Huang, Y. J.; Giles, J. R.; Mathew, D.; Belman, J.; Klapholz, M.; Decaluwe, H.; Huang, A. C.; Berger, S. L.; Garcia, C. K.; Wherry, J. E.
10.1101/2022.10.03.509766 — immunology — Posted on 2022-10-07
3497 Human hippocampal ripples signal encoding of episodic memories
Sakon, J. J.; Halpern, D. J.; Schonhaut, D. R.; Kahana, M. J.
10.1101/2022.10.03.510672 — neuroscience — Posted on 2022-10-07
3502 Mitofusin-2 in nucleus accumbens D2-MSNs regulates social dominance and neuronal function
Ghosal, S.; Gebara, E.; Ramos-Fernandez, E.; Chioino, A.; Grosse, J.; Schneider, B. L.; Zorzano, A.; Astori, S.; Sandi, C.
10.1101/2022.10.07.511275 — neuroscience — Posted on 2022-10-07
3503 Mutation of the ALS/FTD-associated RNA-binding protein FUS alters axonal cytoskeletal organisation
van Tartwijk, F. W.; Wunderlich, L. C. S.; Mela, I.; Makarchuk, S.; Jakobs, M. A. H.; Qamar, S.; Franze, K.; Kaminski Schierle, G. S.; St George-Hyslop, P. H.; Lin, J. Q.; Holt, C. E.; Kaminski, C. F.
10.1101/2022.10.04.510780 — neuroscience — Posted on 2022-10-07
3505 Optic radiations representing different eccentricities age differently
Kruper, J.; Benson, N. C.; Caffarra, S.; Owen, J. P.; Wu, Y.; Lee, A. Y.; Lee, C. S.; Yeatman, J. D.; Rokem, A.
10.1101/2022.10.03.510705 — neuroscience — Posted on 2022-10-07
3507 Hearing the world differently: Examining predictive coding accounts of autism using MEG
Rapaport, H.; Pellicano, E.; Seymour, R. A.; Benikos, N.; He, W.; Sun, Y.; Brock, J.; Sowman, P. F.
10.1101/2022.10.03.510718 — neuroscience — Posted on 2022-10-07
3508 Octopamine metabolically reprograms astrocytes to confer neuroprotection against α-synuclein
Shum, A.; Zaichick, S.; McElroy, G.; DAlessandro, K.; Novakovic, M.; Peng, W.; Chung, D.; Flanagan, M.; Smith, R.; Morales, A.; Stumpf, L.; McGrath, K.; Krainc, D.; Mendillo, M.; Prakriya, M.; Chandel, N.; Caraveo, G.
10.1101/2022.10.04.510813 — neuroscience — Posted on 2022-10-07
3509 Domain Adaptive Neural Inference for Neurons, Microcircuits and Networks
Sheng, K.; Zhang, S.; Beau, M.; Qu, P.; Yang, L.; Liu, X.; He, L.; Zhang, Y.; Ma, L.; Du, K.
10.1101/2022.10.03.510694 — neuroscience — Posted on 2022-10-07
3511 Aerosolizable plasmid DNA dry powders engineered by thin-film freezing
Xu, H.; Moon, C.; Sahakijpijarn, S.; Dao, H. M.; Alzhrani, R. F.; Wang, J.-l.; Williams, R. O.; Cui, Z.
10.1101/2022.10.03.510625 — pharmacology and toxicology — Posted on 2022-10-07
3512 High resolution mapping of the breast cancer tumor microenvironment using integrated single cell, spatial and in situ analysis of FFPE tissue
Janesick, A.; Shelansky, R.; Gottscho, A.; Wagner, F.; Rouault, M.; Beliakoff, G.; Faria de Oliveira, M.; Kohlway, A.; Abousoud, J.; Morrison, C.; Drennon, T. Y.; Mohabbat, S.; Williams, S.; 10x Development Teams, ; Taylor, S.
10.1101/2022.10.06.510405 — cancer biology — Posted on 2022-10-07
3513 Pangenome Graph Construction from Genome Alignment with Minigraph-Cactus
Hickey, G.; Monlong, J.; Novak, A.; Eizenga, J. M.; Human Pangenome Reference Consortium, ; Li, H.; Paten, B.
10.1101/2022.10.06.511217 — bioinformatics — Posted on 2022-10-07
3515 Chromosome assembly for the meagre, Argyrosomus regius, reveals species adaptations and sciaenid sex-related locus evolution
Papadogiannis, V.; Manousaki, T.; Nousias, O.; Tsakogiannis, A.; Kristoffersen, J. B.; Mylonas, C. C.; Batargias, C.; Chatziplis, D.; Tsigenopoulos, C. S.
10.1101/2022.10.04.510760 — genomics — Posted on 2022-10-07
3518 Local adaptation of life-history traits within urban populations of Arabidopsis thaliana
Schmitz, G.; Linstaedter, A.; Frank, A. S.; Dittberner, H.; Schrader, A.; Linne von Berg, K.-H.; Coupland, G.; de Meaux, J.
10.1101/2022.10.03.510679 — evolutionary biology — Posted on 2022-10-07
3524 Distinct Multivariate Structural Brain Profiles Are Related to Variations in Short- and Long-Delay Memory Consolidation Across Children and Young Adults
Schommartz, I.; Lembcke, P. F.; Pupillo, F.; Schuetz, H.; Wald de Chamorro, N.; Bauer, M.; Kaindl, A. M.; Buss, C.; Shing, Y. L.
10.1101/2021.08.24.457558 — neuroscience — Posted on 2022-10-07
3526 Mouse L1s fade with age: a methylation-enforced mechanism for attenuation of L1 retrotransposition potential
Gerdes, P.; Chan, D.; Lundberg, M.; Sanchez-Luque, F. J.; Bodea, G. O.; Ewing, A. D.; Faulkner, G. J.; Richardson, S. R.
10.1101/2022.08.06.500894 — genetics — Posted on 2022-10-07
3530 CTCF and R-loops are boundaries of cohesin-mediated DNA looping
Zhang, H.; Shi, Z.; Banigan, E. J.; Kim, Y.; Yu, H.; Bai, X.-c.; Finkelstein, I. J.
10.1101/2022.09.15.508177 — molecular biology — Posted on 2022-10-07
3531 Ultra-deep Sequencing of Hadza Hunter-Gatherers Recovers Vanishing Microbes
Merrill, B. D.; Carter, M. M.; Olm, M. R.; Dahan, D.; Tripathi, S.; Spencer, S. P.; Yu, F. B.; Jain, S.; Neff, N.; Jha, A. R.; Sonnenburg, E. D.; Sonnenburg, J. L.
10.1101/2022.03.30.486478 — microbiology — Posted on 2022-10-07
3532 16S rRNA sequencing for profiling microbial communities in idiopathic granulomatous mastitis
Ong, S. S.; Xu, J.; Sim, C. K.; Khng, A. J.; Ho, P. J.; Kwan, P. K. W.; Ravikrishnan, A.; Tan, K.-T. B.; Tan, Q. T.; Tan, E. Y.; Tan, S.-M.; Putti, T. C.; Lim, S. H.; Tang, E. L. S.; Nagarajan, N.; Karnani, N.; Li, J.; Hartman, M.
10.1101/2022.09.30.510425 — microbiology — Posted on 2022-10-07
3534 Reconstructing the cascade of language processing in the brain using the internal computations of a transformer-based language model
Kumar, S.; Sumers, T. R.; Yamakoshi, T.; Goldstein, A.; Hasson, U.; Norman, K. A.; Griffiths, T. L.; Hawkins, R. D.; Nastase, S. A.
10.1101/2022.06.08.495348 — neuroscience — Posted on 2022-10-07
3538 ASD gene Bcl11a regulates subcellular RNA localization, associative circuitry, and social behavior
DURAK, O.; Kim, J.-Y.; Tillman, D. E.; Itoh, Y.; Wettstein, M. R.; Greig, L. C.; Addison, T. A.; Macklis, J. D.
10.1101/2022.10.06.511159 — neuroscience — Posted on 2022-10-07
3543 On the nature of the earliest known life forms
Kanaparthi, D.; Lampe, M.; Zhu, B.; Boesen, T.; Klingl, A.; Schwille, P.; Lueders, T.
10.1101/2021.08.16.456462 — evolutionary biology — Posted on 2022-10-07
3544 In situ imaging across ecosystems to resolve the fine-scale oceanographic drivers of a globally significant planktonic grazer
Greer, A. T.; Schmid, M. S.; Duffy, P. I.; Robinson, K. L.; Genung, M. A.; Luo, J. Y.; Panaiotis, T.; Briseno-Avena, C.; Frischer, M. E.; Sponaugle, S.; Cowen, R. K.
10.1101/2022.08.31.506093 — ecology — Posted on 2022-10-06
3549 The BeMoBIL Pipeline for automated analyses of multimodal mobile brain and body imaging data
Klug, M.; Jeung, S.; Wunderlich, A.; Gehrke, L.; Protzak, J.; Djebbara, Z.; Argubi-Wollesen, A.; Wollesen, B.; Gramann, K.
10.1101/2022.09.29.510051 — neuroscience — Posted on 2022-10-06
3550 Predicting perturbation effects from resting state activity using functional causal flow
Nejatbakhsh, A.; Fumarola, F.; Esteki, S.; Toyoizumi, T.; Kiani, R.; Mazzucato, L.
10.1101/2020.11.23.394916 — neuroscience — Posted on 2022-10-06
3553 microbeSEG: A deep learning software tool with OMERO data management for efficient and accurate cell segmentation
Scherr, T.; Seiffarth, J.; Wollenhaupt, B.; Neumann, O.; Schilling, M. P.; Kohlheyer, D.; Scharr, H.; Nöh, K.; Mikut, R.
10.1101/2022.04.29.489998 — bioinformatics — Posted on 2022-10-06
3556 Biological fractionation of lithium isotopes by cellular Na+/H+ exchangersunravels fundamental transport mechanisms.
Poet, M.; Vigier, N.; Bouret, Y.; Jarretou, G.; Bendahhou, S.; Montanes, M.; Thibon, F.; Counillon, L.
10.1101/2022.10.06.510772 — biochemistry — Posted on 2022-10-06
3558 OligoArchive-DSM: Columnar Design for Error-Tolerant Database Archival using Synthetic DNA
Marinelli, E.; Yan, Y.; Magnone, V.; Dumargne, M.-C.; Barbry, P.; Heinis, T.; Appuswamy, R.
10.1101/2022.10.06.511077 — bioengineering — Posted on 2022-10-06
3561 Simultaneous Membrane and RNA Binding by Tick-Borne Encephalitis Virus Capsid Protein
Pulkkinen, L. I.; Barrass, S. V.; Lindgren, M.; Pace, H.; Överby, A. K.; Anastasina, M.; Bally, M.; Lundmark, R.; Butcher, S. J.
10.1101/2022.10.06.511088 — biochemistry — Posted on 2022-10-06
3563 A highly stable Zn(II) dependent phospholipase C obtained by consensus design
Val, D. S.; Di NArdo, L.; Marchisio, F.; Peiru, S.; Castelli, M. E.; Abriata, L.; Menzella, H. G.; Rasia, R.
10.1101/2022.10.06.511049 — biochemistry — Posted on 2022-10-06
3564 Metagenomic analysis reveals novel dietary-related viruses in the gut virome of marmosets hybrids (Callithrix jacchus x Callithrix penicillata), Brazil
Miranda, T. d. S.; Schiffler, F. B.; D'arc, M.; Moreira, F. R. R.; Cosentino, M. A. C.; Coimbra, A. d. L.; Mouta, R.; Medeiros, G.; Girardi, D. L.; Wanderkoke, V.; Soares, C. F. A.; Francisco, T. M.; Henry, M. D.; Afonso, B. C.; Soffiati, F. L.; Ferreira, S. S.; Ruiz-Miranda, C. R.; Soares, M. A.; dos Santos, A. F. A.
10.1101/2022.10.06.509726 — genomics — Posted on 2022-10-06
3565 Inversion polymorphism in a complete human genome assembly
Porubsky, D.; Harvey, W. T.; Rozanski, A. N.; Ebler, J.; Hoeps, W.; Ashraf, H.; Hasenfeld, P.; Paten, B.; Sanders, A. D.; Marschall, T.; Korbel, J. O.; Eichler, E. E.
10.1101/2022.10.06.511148 — genomics — Posted on 2022-10-06
3566 Limitation of sulfur-containing amino acid availability by specific bacterial populations during enhanced colitis in IBD mouse model
Richie, T. G.; Heeren, L.; Kamke, A.; Pogranichniy, S.; Rumback, K.; Summers, T.; Wiechman, H.; Ran, Q.; Sarkar, S.; Plattner, B.; Lee, S. T. M.
10.1101/2022.10.03.510649 — genomics — Posted on 2022-10-06
3568 C1orf112 is a novel regulator of interstrand crosslink that decreases FIGNL1-RAD51 interaction
Carpio, E. P.; Dessapt, J.; Villot, R.; Sacre, L.; Malina, A.; Boulais, J.; Lavoie, E. G.; Luo, V.; Lazaratos, A.-M.; Cote, J.-F.; Malette, F.; Guarne, A.; Fradet-Turcotte, A.; Orthwein, A.
10.1101/2022.10.06.511186 — molecular biology — Posted on 2022-10-06
3569 Manganese-dependent microRNA trimming by 3'->5' exonucleases generates 14-nucleotide or shorter tiny RNAs
Sim, G.; Kehling, A. C.; Park, M. S.; Secor, J.; Divoky, C.; Zhang, H.; Malhotra, N.; Bhagdikar, D.; El-Wahaband, E. A.; Nakanishi, K.
10.1101/2022.10.06.511180 — molecular biology — Posted on 2022-10-06
3570 Distinct modes of heat shock transcription factor interactions with mitotic chromosomes
Price, R. M.; Budzynski, M. A.; Shen, J.; Mitchell, J. E.; Kwan, J. Z. J.; Teves, S. S.
10.1101/2022.10.05.511012 — molecular biology — Posted on 2022-10-06
3573 Capsid-mediated chromatin state of the AAV vector genome controls host species range
Kay, M.; Gonzalez-Sandoval, A.; Tsuji, S.; Zhang, F.; Hung, K. L.; Chang, H.; Pekrun, K.
10.1101/2022.10.06.511169 — molecular biology — Posted on 2022-10-06
3575 Adhesion of Crithidia fasciculata promotes a rapid change in developmental fate driven by cAMP signaling
Denecke, S.; Malfara, M. F.; Hodges, K. R.; Holmes, N. A.; Williams, A. R.; Gallagher-Teske, J. H.; Pascarella, J. M.; Daniels, A. M.; Sterk, G. J.; Leurs, R.; Ruthel, G.; Hoang, R.; Povelones, M. L.; Povelones, M.
10.1101/2022.10.06.511084 — microbiology — Posted on 2022-10-06
3576 Type-specific EV-D68 real-time RT-PCR assay for the detection of all extant enterovirus D68 strains
Ng, T. F. F.; Nix, W. A.; Rogers, S.; Emery, B.; Chern, S.-W.; Butler, K.; Oberste, M. S.
10.1101/2022.10.06.511205 — microbiology — Posted on 2022-10-06
3577 A novel nuclease is the executing part of a bacterial plasmid defense system
Weiss, M.; Giacomelli, G.; Ben Assaya, M.; Grundt, F.; Haouz, A.; Peng, F.; Petrella, S.; Wehenkel, A. M.; Bramkamp, M.
10.1101/2022.10.06.511153 — microbiology — Posted on 2022-10-06
3578 Impacts of Biostimulation and Bioaugmentation on Woodchip Bioreactor Microbiomes
Wang, H.; Feyereisen, G. W.; Wang, P.; Rosen, C.; Sadowsky, M. J.; Ishii, S.
10.1101/2022.10.06.511109 — microbiology — Posted on 2022-10-06
3579 Origin and dynamics of Mycobacterium tuberculosis subpopulations that predictably generate drug tolerance and resistance
Alland, D.; Sebastian, J.; Thomas, A.; Levine, C.; Shrestha, R.; Levy, S.; Safi, H.; Pentakota, S. R.; Kumar, P.
10.1101/2022.10.05.511058 — microbiology — Posted on 2022-10-06
3580 Copy number variation on ABCC2-DNMBP loci impacts the diversity and composition of the gut microbiota in pigs
Ramayo-Caldas, Y.; Crespo-Piazuelo, D.; Morata, J.; Gonzalez-Rodriguez, O.; Sebastia, C.; Castello, A.; Dalmau, A.; Ramos-Onsins, S. E.; Alexiou, K.; Folch, J. M.; Quintanilla, R.; Ballester, M.
10.1101/2022.10.06.510490 — microbiology — Posted on 2022-10-06
3584 Setd2 inactivation sensitizes lung adenocarcinoma to inhibitors of oxidative respiration and mTORC1 signaling
Walter, D. M.; Gladstein, A. C.; Doerig, K. R.; Natesan, R.; Baskaran, S. G.; Gudiel, A. A.; Adler, K. M.; Acosta, J. O.; Wallace, D. C.; Asangani, I. A.; Feldser, D. M.
10.1101/2022.10.06.511146 — cancer biology — Posted on 2022-10-06
3585 Design and Immunogenicity of SARS-CoV-2 DNA vaccine encoding RBD-PVXCP fusion protein
Dormeshkin, D.; Katsin, M.; Stegantseva, M.; Golenchenko, S.; Shapira, M.; Dubovik, S.; Lutskovich, D.; Kavaleuski, A.; Meleshko, A.
10.1101/2022.10.06.511104 — immunology — Posted on 2022-10-06
3588 Chromatin architecture and cis-regulatory landscape of the DACT2-SMOC2 locus in the developing synovial joint.
Nowosad, K.; Hordyjewska-Kowalczyk, E.; Malesa, A.; Odrzywolski, A.; Brouwer, R. W. W.; Kolovos, P.; Boltsis, I.; Birkhoff, J. C.; van IJcken, W. F. J.; Grosveld, F. G.; Conidi, A.; Huylebroeck, D.; Tylzanowski, P.
10.1101/2022.10.06.511134 — developmental biology — Posted on 2022-10-06
3589 Long-term passaging of replication competent pseudo-typed SARS-CoV-2 reveals the antiviral breadth of monoclonal and bispecific antibody cocktails
Zhu, J.; Ma, H.; Zong, H.; Liu, J.; Yue, Y.; Ke, Y.; Liao, Y.; Tang, H.; Wang, L.; Wang, S.; Yuan, Y.; Wu, M.; Bian, Y.; Zhang, B.; Yin, H.; Jiang, H.; Sun, T.; Han, L.; Xie, Y.
10.1101/2022.10.05.511057 — cell biology — Posted on 2022-10-06
3591 Rabbit Development as a Model for Single Cell Comparative Genomics
Ton, M.-L.; Keitley, D.; Theeuwes, B.; Guibentif, C.; Ahnfelt-Ronne, J.; Kjaergaard Andreassen, T.; Calero-Nieto, F. J.; Imaz-Rosshandler, I.; Pijuan-Sala, B.; Nichols, J.; Benito-Gutierrez, E.; Marioni, J. C.; Göttgens, B.
10.1101/2022.10.06.510971 — developmental biology — Posted on 2022-10-06
3592 Reciprocal inflammatory signaling in an ex-vivo explant model for neurofibromatosis type 1-related cutaneous neurofibromas
Grit, J.; Turner, L.; Essenburg, C.; Dischinger, P.; Shurlow, N.; Pate, M.; Graveel, C. R.; Steensma, M. R.
10.1101/2022.10.06.510849 — cell biology — Posted on 2022-10-06
3594 Emergency hematopoiesis proceeds without contribution of hematopoietic stem cells
Munz, C. M.; Dressel, N.; Chen, M.; Grinenko, T.; Roers, A.; Gerbaulet, A.
10.1101/2022.10.05.510973 — cell biology — Posted on 2022-10-06
3595 Three-dose vaccination-induced immune responses protect against SARS-CoV-2 Omicron-BA.2
Zhou, R.; Liu, N.; Li, X.; Peng, Q.; Yiu, C.-K.; Huang, H.; Yang, D.; Du, Z.; Kwok, H.-Y.; Au, K.-K.; Cai, J.-P.; Hung, I. F.-N.; To, K. K.-W.; Xu, X.; Yuen, K.-Y.; Chen, Z.
10.1101/2022.05.09.491254 — immunology — Posted on 2022-10-06
3598 Disentangling positive vs. relaxed selection in animal mitochondrial genomes
Zwonitzer, K. D.; Iverson, E. N. K.; Sterling, J. J.; Weaver, R. J.; Maclaine, B. A.; Havird, J. C.
10.1101/2022.10.05.510972 — evolutionary biology — Posted on 2022-10-06
3600 Functional genomics of cattle through integration of multi-omics data
Beiki, H.; Murdoch, B. M.; Park, C. A.; Kern, C.; Kontechy, D.; Becker, G.; Rincon, G.; Jiang, H.; Zhou, H.; Thorne, J.; Koltes, J. E.; Michal, J. J.; Davenport, K.; Rijnkels, M.; Ross, P. J.; Hu, R.; Corum, S.; McKay, S.; Smith, T. P. L.; Liu, W.; Ma, W.; Zhang, X.; Xu, X.; Han, X.; Jiang, Z.; Hu, Z.-L.; Reecy, J. M.
10.1101/2022.10.05.510963 — bioinformatics — Posted on 2022-10-06
3601 Neurogenomic landscape of social status-dependent cooperative display behavior
Bolton, P. E.; Ryder, T. B.; Dakin, R.; Houtz, J. L.; Moore, I. T.; Balakrishnan, C. N.; Horton, B. M.
10.1101/2022.10.05.510848 — evolutionary biology — Posted on 2022-10-06
3602 Three transcriptional axes underpin anatomy, development, and disorders of the human cortex
Dear, R.; Seidlitz, J.; Markello, R. D.; Arnatkeviciute, A.; Anderson, K. M.; Bethlehem, R. A. I.; Lifespan Brain Chart Consortium, ; Wagstyl, K.; Bullmore, E. T.; Raznahan, A.; Vertes, P.
10.1101/2022.10.05.510582 — neuroscience — Posted on 2022-10-06
3603 Ultra High-Plex Spatial Proteogenomic Investigation of Giant Cell Glioblastoma Multiforme Immune Infiltrates Reveals Distinct Protein and RNA Expression Profiles
Bonnett, S. A.; Rosenbloom, A. B.; Ong, G.; Conner, M.; Rininger, A.; Newhouse, D.; New, F.; Phan, C.; Ilcisin, S.; Sato, H.; Lyssand, J.; Geiss, G.; Beechem, J. M.
10.1101/2022.10.04.510833 — cancer biology — Posted on 2022-10-06
3605 Enhanced mTORC1 signaling and Protein Synthesis in Parkinson Disease Pathogenesis
Khan, M. R.; Yin, X.; Kang, S.-u.; Mitra, J.; Wang, H.; Brahmachari, S.; Karuppagounder, S. S.; Kimura, Y.; Jhaldiyal, A.; Kim, H. H.; Gu, H.; Chen, R.; Redding-Ochoa, J.; Troncoso, J.; Ha, T.; Dawson, V. L.; Dawson, T. M.
10.1101/2022.10.03.510455 — neuroscience — Posted on 2022-10-06
3606 A neural model of proximity to reward
Botros, P.; Vendrell-Llopis, N.; Costa, R.; Carmena, J.
10.1101/2022.10.03.510669 — neuroscience — Posted on 2022-10-06
3608 Astrocyte-Oligodendrocyte interaction regulates central nervous system regeneration
Molina-Gonzalez, I.; Holloway, R. K.; Jiwaji, Z.; Dando, O. R.; Emelianova, K.; Lloyd, A. F.; Forbes, L. H.; Mahmood, A.; Skripuletz, T.; Gudi, V.; Febery, J.; Johnson, J.; Fowler, J.; Kuhlmann, T.; Williams, A.; Chandran, S.; Stangel, M.; Howden, A. J.; Hardingham, G.; Miron, V. E.
10.1101/2022.10.04.510850 — neuroscience — Posted on 2022-10-06
3609 α-synuclein fibril and synaptic vesicle interactions lead to vesicle destruction and increased uptake into neurons
Stephens, A. D.; Fernandez-Villegas, A.; Chung, C. W.; Vanderpoorten, O.; Pinotsi, D.; Mela, I.; Ward, E. N.; McCoy, T. M.; Cubitt, R.; Routh, A. F.; Kaminski, C. F.; Schierle, G. S. K.
10.1101/2022.10.04.510646 — neuroscience — Posted on 2022-10-06
3610 MeCP2 regulates Gdf11, a dosage-sensitive gene critical for neurological function
Bajikar, S. S.; Anderson, A. G.; Zhou, J.; Durham, M. A.; Trostle, A. J.; Wan, Y.-W.; Liu, Z.; Zoghbi, H. Y.
10.1101/2022.10.05.510925 — neuroscience — Posted on 2022-10-06
3613 CRISPR/Cas-based precision gene replacement in plants via microhomology-mediated end joining
Vu, T. V.; Lim, G.-H.; Choi, S. H.; Moon, J. Y.; Nguyen, N. T.; Das, S.; Tran, M. T.; Sung, Y. W.; Kim, J.; Song, Y. J.; Kim, S. W.; Jeong, J. C.; Kim, J.-Y.
10.1101/2022.08.27.505510 — synthetic biology — Posted on 2022-10-06
3614 UBE2C promotes leptomeningeal dissemination and is a therapeutic target in brain metastatic disease
Paisana, E.; Cascao, R.; Custodia, C.; Qin, N.; Picard, D.; Pauck, D.; Carvalho, T.; Ruivo, P.; Barreto, C.; Doutel, D.; Cabecadas, J.; Roque, R.; Pimentel, J.; Miguens, J.; Barata, J. T.; Faria, C. C.
10.1101/2022.10.04.510674 — cancer biology — Posted on 2022-10-06
3616 Treatment of pancreatic cancer with irreversible electroporation and intratumoral CD40 antibody stimulates systemic immune responses that inhibit liver metastasis in an orthotopic model.
Narayanan, J. S. S.; Hayashi, T.; Erdem, S.; McArdle, S.; Tiriac, H.; Ray, P.; Pu, M.; Mikulski, Z.; Miller, A.; Messer, K.; Carson, D.; Schoenberger, S. P.; White, R. R.
10.1101/2022.10.04.510847 — cancer biology — Posted on 2022-10-06
3617 PD-L1 activity is associated with partial EMT and metabolic reprogramming in carcinomas
Muralidharan, S.; Sehgal, M.; R, S.; Mandal, S.; Majumdar, S. S.; M, Y.; Saha, A.; Jolly, M. K.
10.1101/2022.10.05.510941 — cancer biology — Posted on 2022-10-06
3618 The impact of genetic risk for Alzheimers disease on the structural brain networks of young adults
Mirza-Davies, A.; Foley, S.; Caseras, X.; Baker, E.; Holmans, P.; Escott-Price, V.; Jones, D. K.; Harrison, J. R.; Messaritaki, E.
10.1101/2021.09.22.461338 — neuroscience — Posted on 2022-10-06
3619 Copper chelation inhibits TGF-β pathways and suppresses epithelial-mesenchymal transition in cancer
Poursani, E. M.; Mercatelli, D.; Raninga, P.; Bell, J. L.; Saletta, F.; Kohane, F. V.; Zheng, Y.; Rouaen, J.; Jue, T. R.; Michniewicz, F. T.; Kasiou, E.; Tsoli, M.; Cirillo, G.; Waters, S.; Shai-Hee, T.; Valli, E.; Brettle, M.; Whan, R.; Vahdat, L.; Ziegler, D.; Lock, J. G.; Giorgi, F. M.; Khanna, K. k.; VITTORIO, O.
10.1101/2022.10.03.510707 — cancer biology — Posted on 2022-10-06
3620 An Unexpected Single-step Glycosylation Enables the Construction of Antibody-Biomacromolecule Conjugates as Therapeutics
Yang, Y.; Song, Z. t.; Tian, T.; Zhao, Z.; Chen, J.; Hu, J. p.; Jiang, X.; Yang, G. l.; Xue, Q.; Zhao, X. l.; Sha, W. x.; Yang, Y.; Li, J. P.
10.1101/2022.09.04.506510 — biochemistry — Posted on 2022-10-06
3621 STAT5b is a key effector of NRG-1/ERBB4-mediated cardiomyocyte growth
Vaparanta, K. M.; Jokilammi, A.; Paatero, I.; Merilahti, J. A. M.; Heliste, J.; Hemanthakumar, K. A.; Kivelä, R.; Alitalo, K. K.; Taimen, P.; Elenius, K.
10.1101/2022.10.05.510958 — cell biology — Posted on 2022-10-06
3625 The patterned assembly and stepwise Vps4-mediated disassembly of composite ESCRT-III polymers drives archaeal cell division
Hurtig, F.; Burgers, T. C. Q.; Cezanne, A.; Jiang, X.; Mol, F. N.; Traparic, J.; Tarrason Risa, G.; Arashiro Pulschen, A.; Harker-Kirschneck, L.; Saric, A.; Vlijm, R.; Baum, B.
10.1101/2022.09.16.508273 — cell biology — Posted on 2022-10-06
3626 Integrative dissection of gene regulatory elements at base resolution
Chen, Z.; Javed, N. M.; Moore, M.; Wu, J.; Vinyard, M. E.; Pinello, L.; Najm, F.; Bernstein, B. E.
10.1101/2022.10.05.511030 — molecular biology — Posted on 2022-10-06
3628 Automatic antibiotic resistance prediction in Klebsiella pneumoniae based on MALDI-TOF mass spectra
Guerrero-Lopez, A.; Sevilla-Salcedo, C.; Candela, A.; Hernandez-Garcia, M.; Cercenado, E.; Olmos, P. M.; Canton, R.; Munoz, P.; Gomez-Verdejo, V.; del Campo, R.; Rodriguez-Sanchez, B.
10.1101/2021.10.04.463058 — microbiology — Posted on 2022-10-06
3631 Synchronisation of apical constriction and cell cycle progression is a conserved behaviour of pseudostratified neuroepithelia informed by their tissue geometry
Ampartzidis, I.; Efstathiou, C.; Paonessa, F.; Thompson, E. M.; Wilson, T.; McCann, C.; Greene, N.; Copp, A.; Livesey, F. J.; Elvassore, N.; Giobbe, G. G.; De Coppi, P.; Maniou, E.; Galea, G. L.
10.1101/2022.06.15.496231 — cell biology — Posted on 2022-10-06
3634 Imaging of lactate metabolism in retinal Müller cells with a FRET nanosensor
Calbiague Garcia, V. M.; Chen, Y.; Cadiz, B.; Paquet-Durand, F.; Schmachtenberg, O.
10.1101/2022.10.05.510984 — cell biology — Posted on 2022-10-05
3635 Dynamic subcellular localization of sodium-bicarbonate cotransporter NBCn1/SLC4A7 to plasma membrane, centrosomes, spindle, and primary cilia
Severin, M.; Pedersen, E. L.; Borre, M. T.; Axholm, I.; Christiansen, F. B.; Ponniah, M.; Czaplinska, D.; Larsen, T.; Pardo, L. A.; Pedersen, S. F.
10.1101/2022.10.05.510992 — cell biology — Posted on 2022-10-06
3636 The 5:2 diet does not increase adult hippocampal neurogenesis or enhance spatial memory in mice
Roberts, L. D.; Hornsby, A. K. E.; Thomas, A.; Sassi, M.; Kinzett, A.; Hsiao, N.; David, B. R.; Good, M.; Wells, T.; Davies, J. S.
10.1101/2022.10.03.510613 — neuroscience — Posted on 2022-10-06
3637 Suppression of Betacellulin expression is a key mechanism for omega-3 fatty acid mediated attenuation of nonalcoholic steatohepatitis
Padiadpu, J.; Garcia-Jaramillo, M.; Newman, N.; Pederson, J.; Rodrigues, R.; Li, Z.; Singh, S.; Monnier, P.; Trinchieri, G.; Brown, K.; Dzutsev, A. K.; Shulzhenko, N.; Jump, D. B.; Morgun, A.
10.1101/2022.10.03.510635 — systems biology — Posted on 2022-10-05
3641 Proteomics and phosphoproteomics profiling of the co-formulation of type I and II interferons, HeberFERON, in the glioblastoma-derived cell line U-87 MG
Vazquez-Blomquist, D.; Hardy-Sosa, A.; Baez, S. C.; Besada, V.; Palomares, S.; Guirola, O.; Ramos, Y.; Wisniewski, J. R.; Gonzalez, L. J.; Bello-Rivero, I.
10.1101/2022.10.03.510562 — cancer biology — Posted on 2022-10-05
3642 Multicolor Light-Induced Immune Activation via Polymer Photocaged Cytokines
Birnbaum, L. A.; Sullivan, E. C.; Do, P.; Uricoli, B.; Porter, C. C.; Henry, C. J.; Dreaden, E. C.
10.1101/2022.10.03.510638 — bioengineering — Posted on 2022-10-05
3643 Integration of silicon chip microstructures for in-line microbial cell lysis in soft microfluidics
Nittala, P. V. K.; Hohreiter, A.; Linhard, E. R.; Dohn, R.; Mishra, S.; Konda, A.; Divan, R. N. S.; Guha, S.; Basu, A.
10.1101/2022.10.03.510547 — bioengineering — Posted on 2022-10-05
3647 SEC62 and TMX4 control asymmetric autophagy of the nuclear envelope upon LINC complex disassembly
Kucinska, M.; Fedry, J.; Galli, C.; Morone, D.; Raimondi, A.; Solda, T.; Foerster, F.; Molinari, M.
10.1101/2022.10.05.510950 — cell biology — Posted on 2022-10-05
3649 Integrative genetic analysis identifies FLVCR1 as an essential component of choline transport in mammals
Kenny, T. C.; Khan, A.; Son, Y.; Yue, L.; Heissel, S.; Gamazon, E. R.; Alwaseem, H.; Hite, R. K.; Birsoy, K.
10.1101/2022.10.05.509986 — cell biology — Posted on 2022-10-05
3651 Altered secretion, constitution, and functional properties of the gastrointestinal mucus in a rat model of sporadic Alzheimer's disease
Homolak, J.; De Busscher, J.; Zambrano Lucio, M.; Joja, M.; Virag, D.; Babic Perhoc, A.; Knezovic, A.; Osmanovic Barilar, J.; Salkovic-Petrisic, M.
10.1101/2022.10.03.510623 — neuroscience — Posted on 2022-10-05
3655 Ageing and MPTP-sensitivity depend on molecular and ultrastructural signatures of astroglia and microglia in mice nigra
Abhilash, P.; Bharti, U.; Rashmi, S.; Raju, T. R.; Kutty, B. M.; Chandrashekar Sagar, B.; Alladi, P. A.
10.1101/2020.12.15.422212 — neuroscience — Posted on 2022-10-05
3656 Reconstruct a eukaryotic chromosome arm by de novo design and synthesis
Jiang, S.; Luo, Z.; Yu, K.; Zhao, S.; Cai, Z.; Yu, W.; Wang, H.; Cheng, L.; Liang, Z.; Gao, H.; Monti, M.; Schindler, D.; Huang, L.; Zeng, C.; Zhang, W.; Zhou, C.; Tang, Y.; Li, T.; Ma, Y.; Cai, Y.; Boeke, J. D.; Dai, J.
10.1101/2022.10.04.509869 — synthetic biology — Posted on 2022-10-05
3657 CryoFIB milling large tissue samples for cryo-electron tomography
Wang, S.; Zhou, H.; Chen, W.; Jiang, Y.; Yan, X.; You, H.; Li, X.
10.1101/2022.10.03.510728 — biophysics — Posted on 2022-10-05
3660 Sonic hedgehog-dependent recruitment of GABAergic interneurons into the developing visual thalamus
Somaiya, R. D.; Stebbins, K.; Gingrich, E. C.; Xie, H.; Campbell, J. N.; Garcia, A. D. R.; Fox, M.
10.1101/2022.02.22.481508 — neuroscience — Posted on 2022-10-05
3661 Co-fluctuations of neural activity define intra-V1 networks related to perceptual organization
Valdes-Sosa, M. J.; Ontivero-Ortega, M.; Iglesias-Fuster, J.; Lage-Castellanos, A.; Galan-Garcia, L.; Valdes-Sosa, P. A.
10.1101/2022.08.22.504869 — neuroscience — Posted on 2022-10-05
3664 Arena3Dweb: Interactive 3D visualization of multilayered networks supporting multiple directional information channels, clustering analysis and application integration
Kokoli, M.; Karatzas, E.; Baltoumas, F. A.; Schneider, R.; Pafilis, E.; Paragkamian, S.; Doncheva, N. T.; Jensen, L. J.; Pavlopoulos, G.
10.1101/2022.10.01.510435 — bioinformatics — Posted on 2022-10-05
3665 Differential Boric Acid and Water Transport in Type I and Type II Pores of Arabidopsis Nodulin 26-Intrinsic Protein
Beamer, Z. G.; Routray, P.; Agarwal, R.; Li, T.; Gibson, K. M.; Ostrouchov, K. E.; Smith, J. C.; Roberts, D. M.
10.1101/2022.10.05.510970 — biochemistry — Posted on 2022-10-05
3666 Structure of mycobacterial respiratory Complex I
Liang, Y.; Plourde, A.; Bueler, S. A.; Liu, J.; Brzezinski, P.; Vahidi, S.; Rubinstein, J. L.
10.1101/2022.10.04.510895 — biochemistry — Posted on 2022-10-05
3667 CHRONO participates in multi-modal repression of circadian transcriptional complexes
Crosby, P.; Goularte, N. F.; Sharma, D.; Chen, E.; Parico, G. C. G.; Philpott, J. M.; Harold, R.; Gustafson, C. L.; Partch, C. L.
10.1101/2022.10.04.510902 — biochemistry — Posted on 2022-10-05
3668 A Theory for High-Throughput Genetic Interaction Screening
McCarthy, M.; Dodd, W. B.; Lu, X.; Patel, N. D.; Haskell, C. V.; Sanabria, H.; Blenner, M.; Birtwistle, M. R.
10.1101/2022.10.05.510977 — biochemistry — Posted on 2022-10-05
3670 Genomic Analysis of Two Phlebotomine Sand Fly Vectors of Leishmania from the New and Old World
McDowell, M. A.; Labbe, F.; Abdeladhim, M.; Abrudan, J.; Araki, A. S.; Araujo, R. N.; Arensburger, P.; Beniot, J. B.; Brazil, R. P.; Bruno, R. V.; Bueno da Silva Rivas, G.; Carvalho de Abreu, V.; Charamis, J.; Coutinho-Abreu, I.; da Costa-Latge, S. G.; Darby, A.; Dillon, V.; Emrich, S. J.; Fernandez-Medina, D.; Figueiredo Gontijo, N.; Flannley, C. M.; Gatherer, D.; Genta, F. A.; Gesing, S.; Giraldo-Calderon, G. I.; Gomes, B.; Aguiar, E. R. G. R.; Hamarsheh, O.; Hawksworth, M.; Hendershot, J. M.; Hickner, P. V.; Imler, J.-L.; Ioannidis, P.; Jennings, E. C.; Kamhawi, S.; Karageorgiou, C.; Kenned
10.1101/2022.10.05.510924 — genomics — Posted on 2022-10-05
3671 Resolving Complexities in Taxonomic Lineages of the Organellar and Nuclear Genomes of Galdieria through Comparative Phylogenomic Analysis
Iovinella, M.; Lock, S. C. L.; Downing, J. M.; Morley, J.; Chew, Y. P.; Mackinder, L. C. M.; Chong, J. P. J.; Feichtinger, G. A.; Ashton, P. D.; James, S.; Jeffares, D.; Ciniglia, C.; Davis, S. J.
10.1101/2022.10.04.510841 — genomics — Posted on 2022-10-05
3672 Comparisons between Complete Genomes of the Eukaryotic Extremophile Galdieria sulphuraria Reveals Complex Nuclear Chromosomal Structures
Downing, J. M.; Lock, S. C. L.; Iovinella, M.; Davey, J.; Mackinder, L. C. M.; Chong, J. P. J.; Ashton, P. D.; Feichtinger, G. A.; James, S.; Jeffares, D.; Ciniglia, C.; Davis, S. J.
10.1101/2022.10.04.510839 — genomics — Posted on 2022-10-05
3673 Modelling the effectiveness of targeting Rift Valley fever virus vaccination using imperfect network information
Sulaimon, T. A.; Chaters, G. L.; Enright, J.; Nyasebwa, O. M.; Swai, E. S.; Cleaveland, S.; Kao, R. R.; Johnson, P. C. D.
10.1101/2022.10.04.510793 — genetics — Posted on 2022-10-05
3674 Common risk variants in AHI1 are associated with childhood steroid-sensitive nephrotic syndrome
Downie, M. L.; Gupta, S.; Voinescu, C.; Levine, A. P.; Sadeghi-Alavijeh, O.; Dufek-Kamperis, S.; Cao, J.; Christian, M.; Kari, J. A.; Thalgahagoda, S.; Ranawaka, R.; Abeyagunawardena, A.; Gbadegesin, R.; Parekh, R. S.; Kleta, R.; Bockenhauer, D.; Stanescu, H. C.; Gale, D. P.
10.1101/2022.10.05.510923 — genetics — Posted on 2022-10-05
3679 Temporal dynamics of the multi-omic response to endurance exercise training across tissues
MoTrPAC Study Group, ; Amar, D.; Gay, N. R.; Jean Beltran, P. M.; Adkins, J. N.; Almagro Armenteros, J. J.; Ashley, E.; Avila-Pacheco, J.; Bae, D.; Bararpour, N.; Burant, C.; Clish, C.; Cutter, G.; Dasari, S.; Dennis, C.; Evans, C. R.; Fernandez, F. M.; Gaul, D.; Ge, Y.; Gerszten, R.; Goodyear, L. J.; Hou, Z.; Ilkayeva, O.; Ivanova, A. A.; Jimenez-Morales, D.; Kachman, M. T.; Keshishian, H.; Kraus, W. E.; Lanza, I. R.; Li, J.; Lindholm, M. E.; Lira, A. C.; Many, G. M.; Marwaha, S.; Miller, M. E.; Muehlbauer, M. J.; Nair, K. S.; Nair, V. D.; Natarajan Raja, A.; Newgard, C.; Ortlund, E. A.; Pie
10.1101/2022.09.21.508770 — molecular biology — Posted on 2022-10-05
3680 High-resolution structure of a microtubule-like tube composed of FtsZ-monobody complexes
Fujita, J.; Amesaka, H.; Yoshizawa, T.; Kuroda, N.; Kamimura, N.; Hara, M.; Inoue, T.; Namba, K.; Tanaka, S.-i.; Matsumura, H.
10.1101/2022.10.05.510932 — molecular biology — Posted on 2022-10-05
3683 Revealing Pentose Catabolism in Pseudomonas putida
Park, M.-R.; Gauttam, R.; Fong, B.; Chen, Y.; Lim, H. G.; Feist, A.; Mukhopadhyay, A.; Petzold, C. J.; Simmons, B. A.; Singer, S. W.
10.1101/2022.10.05.510959 — microbiology — Posted on 2022-10-05
3684 Microbial mat compositions and localization patterns explain the virulence of black band disease in corals
Wada, N.; Iguchi, A.; Urabe, Y.; Yoshioka, Y.; Abe, N.; Takase, K.; Hayashi, S.; Kawanabe, S.; Sato, Y.; Tang, S.-L.; Mano, N.
10.1101/2022.10.04.510905 — microbiology — Posted on 2022-10-05
3685 Discovery and biosynthesis of imidazolium antibiotics from a probiotic Bacillus licheniformis
Ham, S. L.; Lee, T. H.; Kim, K. J.; Kim, J. H.; Hwang, S. J.; Lee, S. H.; Lee, W.; Kim, C. S.
10.1101/2022.10.05.511033 — microbiology — Posted on 2022-10-05
3686 Host Phylogeny Shapes Viral Transmission Networks in an Island Ecosystem
French, R. K.; Anderson, S. H.; Cain, K. E.; Greene, T. C.; Minor, M.; Miskelly, C. M.; Montoya, J. M.; Muller, C. G.; Taylor, M. W.; Recovery Team, K.; Holmes, E. C.
10.1101/2022.10.04.510907 — microbiology — Posted on 2022-10-05
3687 A novel taurine-respiring murine gut bacterium contributes to colonization resistance against enteropathogens
Ye, H.; Borusak, S.; Eberl, C.; Hanson, B. T.; Zwirzitz, B.; Herbold, C.; Pjevac, P.; Hausmann, B.; Stecher, B.; Schleheck, D.; Loy, A.
10.1101/2022.10.05.510937 — microbiology — Posted on 2022-10-05
3688 C. difficile may be overdiagnosed in adults and is a prevalent commensal in infants
Ferretti, P.; Wirbel, J.; Maistrenko, O. M.; Van Rossum, T.; Alves, R.; Fullam, A.; Akanni, W.; Schudoma, C.; Schwarz, A.; Thielemann, R.; Thomas, L.; Kandels, S.; Hercog, R.; Telzerow, A.; Letunic, I.; Kuhn, M.; Zeller, G.; Schmidt, T. S.; Bork, P.
10.1101/2022.02.16.480740 — microbiology — Posted on 2022-10-05
3690 The crystal structure of a simian Foamy Virus receptor binding domain provides clues about entry into host cells
Fernandez, I.; Tofdal Dynesen, L.; Coquin, Y.; Pederzoli, R.; Brun, D.; Haouz, A.; Gessain, A.; Rey, F. A.; Buseyne, F.; Backovic, M.
10.1101/2022.10.04.509876 — microbiology — Posted on 2022-10-05
3691 Effects of high temperature and heavy precipitation on drinking water quality and child hand contamination levels in rural Kenya
Powers, J. E.; Mureithi, M.; Mboya, J.; Campolo, J.; Swarthout, J. M.; Pajka, J.; Null, C.; Pickering, A. J.
10.1101/2022.10.04.510863 — microbiology — Posted on 2022-10-05
3694 Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer's disease
Xia, Z.; Prescott, E.; Wareing, H. E.; Matuszyk, M. M.; Dakin, H.; Dimou, E.; Zuo, E.; Zhang, Y. P.; Lam, J. Y. L.; Danial, J. S. H.; Leah, T.; Barnes, K. M.; Strickland, M.; Jiang, H.; Thornton, P.; Crowther, D. C.; Holtzman, D. M.; Bell, S. M.; Higginbottom, A.; Ferraiuolo, L.; Mortiboys, H. J.; Wharton, S. B.; Ranasinghe, R. T.; Klenerman, D.; De, S.
10.1101/2021.07.13.452239 — neuroscience — Posted on 2022-10-05
3696 A novel antiviral formulation inhibits SARS-CoV-2 infection of human bronchial epithelium
Purves, K.; Haverty, R.; O'Neill, T.; Folan, D.; O'Reilly, S.; Baird, A. W.; Scholz, D.; Mallon, P. W.; Gautier, V.; Folan, M.; Fletcher, N. F.
10.1101/2022.10.05.510928 — pharmacology and toxicology — Posted on 2022-10-05
3698 CRISPRcleanR WebApp: an interactive web application for processing genome-wide pooled CRISPR-Cas9 viability screen
Vinceti, A.; De Lucia, R. R.; Cremaschi, P.; Perron, U.; Karakoc, E.; Mauri, L.; Fernandez, C.; Kluczynski, K. H.; Anderson, D. S.; Iorio, F.
10.1101/2022.03.11.483924 — bioinformatics — Posted on 2022-10-05
3702 CryoFIB milling large tissue samples for cryo-electron tomography
Li, X.; Wang, S.; Zhou, H.; Chen, W.; Jiang, Y.; Yan, X.; You, H.
10.1101/2022.10.03.510728 — biophysics — Posted on 2022-10-05
3706 Heterogeneous and Surface-Catalyzed Amyloid Aggregation Monitored by Spatially Resolved Fluorescence and Single Molecule Microscopy
Zhou, X.; Wilgaard Sinkjaer, A.; Zhang, M.; Dahl Pinholt, H.; Moerck Nielsen, H.; Haztakis, N. S.; van de Weert, M.; Fodera, V.
10.1101/2022.10.05.510935 — biophysics — Posted on 2022-10-05
3707 Entropic control of the free energy landscape of an archetypal biomolecular machine
Ray, K. K.; Kinz-Thompson, C. D.; Fei, J.; Wang, B.; Lin, Q.; Gonzalez, R. L.
10.1101/2022.10.03.510626 — biophysics — Posted on 2022-10-05
3710 Learning Free Energy Pathways through Reinforcement Learning of Adaptive Steered Molecular Dynamics
Ho, N.; Cava, J. K.; Vant, J.; Shukla, A.; Miratsky, J.; Turaga, P.; Maciejewski, R.; Singharoy, A.
10.1101/2022.10.04.510845 — biophysics — Posted on 2022-10-05
3711 Chemical Imaging Reveals Diverse Functions of Tricarboxylic Acid Metabolites in Root Growth and Development
Zhang, T.; Noll, S. E.; Peng, J. T.; Klair, A.; Tripka, A.; Stutzman, N.; Cheng, C.; Zare, R. N.; Dickinson, A. J.
10.1101/2022.10.04.510836 — plant biology — Posted on 2022-10-05
3713 Convergence and molecular evolution of floral fragrance after independent transitions to self fertilization
Wozniak, N. J.; Sartori, K.; Kappel, C.; Zhao, L.; Erban, A.; Fehrle, I.; Jantzen, F.; Orsucci, M.; Rosa, S.; Lenhard, M.; Kopka, J.; Sicard, A.
10.1101/2022.10.04.510758 — plant biology — Posted on 2022-10-05
3714 Identifying Novel Candidate Defense Genes Against Rice Blast By Disease-Resistance Transcriptome Analysis
Mauleon, R. P.; Satoh, K.; Bartolome, V.; Baraoidan, M.; Deomano, E.; Kikuchi, S.; Leung, H.
10.1101/2022.10.05.510921 — plant biology — Posted on 2022-10-05
3716 Differential expression analysis of sexual and apomictic Boechera uncovers FAS4 as crucial for gametogenesis
Binmoeller, L.; Volkert, C.; Kiefer, C.; Zuehl, L.; Slawinska, M. W.; Loreth, A.; Nauerth, B. H.; Ibberson, D.; Martinez, R.; Zipper, R.; Schmidt, A.; Kohnle, M.
10.1101/2022.10.05.510110 — plant biology — Posted on 2022-10-05
3720 Simultaneous multicolor fluorescence imaging using duplication-based PSF engineering
Van den Eynde, R.; Hertel, F.; Krajnik, B.; Hugelier, S.; Auer, A.; Schlichthaerle, T.; Jungmann, R.; Leutenegger, M.; Vandenberg, W.; Dedecker, P.
10.1101/2022.10.04.510770 — biophysics — Posted on 2022-10-05
3722 Modeling Single-Cell Dynamics Using Unbalanced Parameterized Monge Maps
Eyring, L. V.; Klein, D.; Palla, G.; Becker, S.; Weiler, P.; Kilbertus, N.; Theis, F.
10.1101/2022.10.04.510766 — bioinformatics — Posted on 2022-10-05
3725 Treg cells drive MYCN-mediated immunosuppression and tumor aggressiveness in high-risk neuroblastoma
Qin, X.; Lam, A. K.; Zhang, X.; Sengupta, S.; Iorgulescu, B. J.; Zuo, T.; Floru, A. E.; Meara, G. K.; Lloyd, k.; Kwok, L. A.; Smith, K. S.; Nagaraju, T. R.; Meijers, R.; Ceol, C.; Liu, C.-T.; Alexandrescu, S.; Wu, C. J.; Keskin, D.; George, R. E.; Feng, H.
10.1101/2022.10.03.510561 — cancer biology — Posted on 2022-10-05
3727 A Protocol for Single Nucleus RNAseq from Frozen Skeletal Muscle
Soule, T. G.; Pontifex, C. S.; Rosin, N.; Joel, M. M.; Lee, S.; Nguyen, M. D.; Chhibber, S.; Pfeffer, G.
10.1101/2022.10.02.510482 — genomics — Posted on 2022-10-05
3730 Novel ACE2 nanoparticles universally block SARS-CoV-2 variants in the human respiratory tract
Sauvanet, C.; Lemos, M.; Bezault, A.; Rodriguez de Francisco, B.; Chan, M. C.; Hui, K. P.; Ng, K.-c.; Nicholls, J. M.; Volkmann, N.; Hanein, D.
10.1101/2022.05.05.490805 — cell biology — Posted on 2022-10-05
3731 Stress vesicles are induced by acute mechanical force and precede the commitment of epidermal stem cells to terminal differentiation
Huang, S.; Kuri, P.; Zou, J.; Blanco, A.; Marshall, M.; Rice, G.; Prouty, S.; Dentchev, T.; Doepner, M.; Boerckel, J. D.; Capell, B. C.; Ridky, T. W.; Rompolas, P.
10.1101/2022.09.29.510204 — cell biology — Posted on 2022-10-05
3732 Nanobody engineering for SARS-CoV-2 neutralization and detection
Hannula, L.; Kuivanen, S.; Lasham, J.; Kant, R.; Kareinen, L.; Bogacheva, M.; Strandin, T.; Sironen, T.; Sharma, V.; Saviranta, P.; Kipar, A.; Vapalahti, O.; Huiskonen, J. T.; Rissanen, I.
10.1101/2022.09.14.507920 — microbiology — Posted on 2022-10-05
3733 Inflammation drives age-induced loss of tissue resident macrophages
Ade, K.; Coronilla, J. S.; Obino, D.; Weinberger, T.; Kaiser, C.; Mella, S.; Chen, C.; Katsimpardi, L.; Werts, C.; Dardenne, P.; Lallemand, Y.; Gomez-Perdiguero, E.
10.1101/2022.10.02.510513 — immunology — Posted on 2022-10-05
3738 Beyond BRCA: Discovery of novel causes and consequences of homologous recombination deficiencies
McGrail, D. J.; Li, Y.; Smith, R. S.; Feng, B.; Dai, H.; Li, Y.; Hu, L.; Dennehey, B.; Awasthi, S.; Mendillo, M. L.; Mills, G. B.; Lin, S.-Y.; Yi, S. S.; Sahni, N.
10.1101/2022.10.01.510467 — systems biology — Posted on 2022-10-05
3740 Perturbation of mitochondrial Ca2+ homeostasis activates cross-compartmental proteostatic response in Arabidopsis
Zhang, X.; Ma, C.; Bao, X.; Zhang, S.; Zayed, O.; Zhang, Z.; Tang, K.; Xie, S.; Wang, Y.; Zhang, D.; Xu, H.; Jia, H.; Wang, X.; Lei, Q.; Wang, X.; Zhang, J.; Dinesh-Kumar, S.; Song, C.-P.; Zhu, J.-K.; Zhu, X.
10.1101/2022.10.02.510489 — plant biology — Posted on 2022-10-05
3744 The Arabidopsis SHORTROOT network coordinates shoot apical meristem development with auxin dependent lateral organ initiation
Bahafid, E.; Bradtmöller, I.; Thies, A. M.; Nguyen, T. T. O. N.; Gutierrez, C.; Desvoyes, B.; Stahl, Y.; Blilou, I.; Simon, R. G.
10.1101/2022.09.27.509828 — plant biology — Posted on 2022-10-05
3745 Amyloid beta 42 alters cardiac metabolism and impairs cardiac function in obesity
Hall, L. G.; Czeczor, J. K.; Connor, T.; Botella, J.; De Jong, K. A.; Renton, M. C.; Genders, A. J.; Venardos, K.; Martin, S. D.; Bond, S. T.; Aston-Mourney, K.; Howlett, K. F.; Campbell, J. A.; Collier, G. R.; Walder, K. R.; McKenzie, M.; Ziemann, M.; McGee, S.
10.1101/2022.10.02.510555 — physiology — Posted on 2022-10-05
3746 Distribution of intraperitoneally administered D2O in AQP4-knockout mouse brain after MCA occlusion
Urushihata, T.; Takuwa, H.; Takamashi, M.; Kershaw, J.; Shibata, S.; Nitta, N.; Tachibana, Y.; Yasui, M.; Higuchi, M.; Obata, T.
10.1101/2022.10.02.510567 — physiology — Posted on 2022-10-05
3750 TACCO: Unified annotation transfer and decomposition of cell identities for single-cell and spatial omics
Mages, S.; Moriel, N.; Avraham-Davidi, I.; Murray, E.; Chen, F.; Rozenblatt-Rosen, O.; Klughammer, J.; Regev, A.; Nitzan, M.
10.1101/2022.10.02.508471 — bioinformatics — Posted on 2022-10-05
3751 Mining novel cis-regulatory elements from the emergent host Rhodosporidium toruloides using transcriptomic data
Czamanski Nora, L.; Anzolini Cassiano, M. H.; Paulino Santana, I.; Guazzaroni, M.-E.; Silva-Rocha, R.; da Silva, R. R.
10.1101/2022.10.03.510576 — bioinformatics — Posted on 2022-10-05
3752 aMeta: an accurate and memory-efficient ancient Metagenomic profiling workflow
Pochon, Z.; Bergfeldt, N.; Kirdok, E.; Vicente, M.; Naidoo, T.; van der Valk, T.; Altinisik, N. E.; Krzewinska, M.; Dalen, L.; Gotherstrom, A.; Mirabello, C.; Unneberg, P.; Oskolkov, N.
10.1101/2022.10.03.510579 — bioinformatics — Posted on 2022-10-05
3753 Hecatomb: An End-to-End Research Platform for Viral Metagenomics
Roach, M. J.; Beecroft, S.; Mihindukulasuriya, K.; Wang, L.; Paredes, A.; Henry-Cocks, K.; Lima, L. F. O.; Dinsdale, E. A.; Edwards, R.; Handley, S. A.
10.1101/2022.05.15.492003 — bioinformatics — Posted on 2022-10-05
3756 Dynamic metabolic exchanges between complementary bacterial types provide collaborative stress resistance
Amarnath, K.; Narla, A.; Pontrelli, S.; Dong, J.; Taylor, B. R.; Caglar, T.; Schwartzman, J. A.; Sauer, U.; Cordero, O. X.; Hwa, T.
10.1101/2021.06.24.449802 — microbiology — Posted on 2022-10-05
3757 Molecular Acclimation of Halobacterium salinarum to Halite Brine Inclusions
Favreau, C.; Tribondeau, A.; Marugan, M.; Guyot, F.; Alpha-Bazin, B.; Marie, A.; Puppo, R.; Dufour, T.; Huguet, A.; Zirah, S.; Kish, A.
10.1101/2022.09.16.508090 — microbiology — Posted on 2022-10-05
3758 Loss of the MLL3 tumor suppressor accelerates breast tumor onset via HIF1a-induced CCL2-mediated recruitment of CCR2+ regulatory T cells
Boutet, M.; Erler, P.; Nishitani, K.; Couturier, N.; Zhang, Z.; Barbieux, E.; Guillen, E.; Suzuki, M.; Lauvau, G.; Guo, W.
10.1101/2022.10.02.510540 — immunology — Posted on 2022-10-05
3759 Single-cell analysis reveals dynamics of human B cell differentiation and identifies novel B and antibody-secreting cell intermediates
Verstegen, N.; Pollastro, S.; Unger, P.-P.; Marsman, C.; Elias, G.; Jorritsma, T.; Streutker, M.; Bassler, K.; Haendler, K.; Rispens, T.; Schultze, J.; ten Brinke, A.; Beyer, M.; van Ham, M. S.
10.1101/2022.10.03.510595 — immunology — Posted on 2022-10-05
3762 Glucoregulatory Reprogramming in Male Mice Offspring Induced by Maternal Transfer of Indoor Flame Retardant Endocrine Disruptors
Kozlova, E. V.; Chinthirla, B. D.; Bishay, A. E.; Perez, P. A.; Denys, M. E.; Krum, J. M.; DiPatrizio, N. V.; Curras-Collazo, M. C.
10.1101/2022.10.02.510485 — pharmacology and toxicology — Posted on 2022-10-05
3776 Three-dimensional genome re-wiring in loci with Human Accelerated Regions
Keough, K. C.; Whalen, S.; Inoue, F.; Przytycki, P. F.; Fair, T.; Deng, C.; Steyert, M.; Ryu, H.; Lindblad-Toh, K.; Karlsson, E.; Zoonomia Consortium, ; Nowakowski, T. J.; Ahituv, N. J.; Pollen, A. A.; Pollard, K. S.
10.1101/2022.10.04.510859 — evolutionary biology — Posted on 2022-10-05
3777 Distinct effects of disease-associated TREM2 R47H/+ and T66M mutations on iPSC-derived microglia.
Penney, J.; Ralvenius, W. T.; Loon, A. R.; Cerit, O.; Dileep, V.; Milo, B.; Woolf, H.; Tsai, L.-H.
10.1101/2022.10.05.511003 — neuroscience — Posted on 2022-10-05
3778 Rapid Cell Type-Specific Nascent Proteome Labeling in Drosophila
Villalobos-Cantor, S.; Barrett, R. M.; Condon, A. F.; Arreola-Bustos, A.; Rodriguez, K. M.; Cohen, M. S.; Martin, I.
10.1101/2022.10.03.510650 — neuroscience — Posted on 2022-10-05
3780 Atypical NMDA Receptors Limit Synaptic Plasticity in the Adult Ventral Hippocampus
Hurley, E. P.; Mukherjee, B.; Fang, L.; Barnes, J. R.; Nafar, F.; Hirasawa, M.; Parsons, M. P.
10.1101/2022.10.05.510966 — neuroscience — Posted on 2022-10-05
3782 An in silico evaluation of anthraquinone derivatives as potential inhibitors of DNA gyrase B of Mycobacterium tuberculosis
Amorim, J. C.; Cabrera Bermeo, A. E.; Vasquez Urgiles, V. E.; Martinez Leon, M. R.; Carpio Arevalo, J. M.
10.1101/2022.10.01.510436 — bioinformatics — Posted on 2022-10-05
3784 The Crux toolkit for analysis of bottom-up tandem mass spectrometry proteomics data
Kertesz-Farkas, A.; Acquaye, F. L. N. A.; Bimani, K.; Eng, J.; Fondrie, W. E.; Grant, C. E.; Hoopmann, M. R.; Lin, A.; Lu, Y.; Moritz, R. L.; MacCoss, M. J.; Noble, W. S.
10.1101/2022.10.02.510538 — bioinformatics — Posted on 2022-10-05
3785 Tunable image-mapping optical coherence tomography
Lee, J.; Du, X.; Park, J.; Cui, Q.; Iyer, R. R.; Boppart, S. A.; Gao, L.
10.1101/2022.10.01.510456 — bioengineering — Posted on 2022-10-05
3792 Arena3Dweb: Interactive 3D visualization of multilayered networks supporting multiple directional information channels, clustering analysis and application integration
Kokoli, M.; Karatzas, E.; Baltoumas, F. A.; Schneider, R.; Pafilis, E.; Paragkamian, S.; Doncheva, N. T.; Jensen, L. J.; Pavlopoulos, G.
10.1101/2022.10.01.510435 — bioinformatics — Posted on 2022-10-05
3794 A balance between actin and Eps8/IRSp53 utilization in branched versus linear actin networks determines tunneling nanotube formation
Henderson, J. M.; Ljubojevic, N.; Chaze, T.; Castaneda, D.; Battistella, A.; Giai Gianetto, Q.; Matondo, M.; Descroix, S.; Bassereau, P.; Zurzolo, C.
10.1101/2022.08.24.504515 — cell biology — Posted on 2022-10-05
3795 Differential impact of GABAA receptors and gephyrin post-translational modifications on layer 2/3 pyramidal neuron responsiveness in vivo
Tsai, Y.-C.; Hleihil, M.; Otomo, K.; Abegg, A.; Cavaccini, A.; Panzanelli, P.; Cramer, T.; Ferrari, K. D.; Barrett, M. J. P.; Bosshard, G.; Karayannis, T.; Weber, B.; Stobart, J. L.; Tyagarajan, S. K.
10.1101/2020.11.25.397877 — neuroscience — Posted on 2022-10-05
3796 OrBITS: A High-throughput, time-lapse, and label-free drug screening platform for patient-derived 3D organoids
Deben, C.; De La Hoz, E. C.; Le Compte, M.; Van Schil, P.; Hendriks, J. M.; Lauwers, P.; Yogeswaran, S. K.; Lardon, F.; Van Laere, S.; Pauwels, P.; Bogaerts, A.; Smits, E.; Vanlanduit, S.; Lin, A.
10.1101/2021.09.09.459656 — cancer biology — Posted on 2022-10-05
3797 A comprehensive view of cell-type-specific temporal dynamics in human and mouse brains
Lu, Z.; Zhang, M.; Lee, J.; Sziraki, A.; Anderson, S.; Ge, S.; Nelson, P. T.; Zhou, W.; Cao, J.
10.1101/2022.10.01.509820 — genomics — Posted on 2022-10-05
3799 Predator-mediated interactions through changes in predator home range size can lead to local prey exclusion
Beardsell, A.; Berteaux, D.; Dulude-de-Broin, F.; Gauthier, G.; Clermont, J.; Gravel, D.; Bety, J.
10.1101/2022.09.30.510100 — ecology — Posted on 2022-10-05
3800 A reference induced pluripotent stem cell line for large-scale collaborative studies
Pantazis, C. B.; Yang, A.; Lara, E.; McDonough, J. A.; Blauwendraat, C.; Peng, L.; Oguro, H.; Kanaujiya, J.; Zou, J.; Sebesta, D.; Pratt, G.; Cross, E.; Blockwick, J.; Buxton, P.; Kinner-Bibeau, L.; Medura, C.; Tompkins, C.; Hughes, S.; Santiana, M.; Faghri, F.; Nalls, M. A.; Vitale, D.; Ballard, S.; Qi, Y. A.; Ramos, D. M.; Anderson, K. M.; Stadler, J.; Narayan, P.; Papademetriou, J.; Reilly, L.; Nelson, M. P.; Aggarwal, S.; Rosen, L. U.; Kirwan, P.; Pisupati, V.; Coon, S. L.; Scholz, S. W.; Priebe, T.; Öttl, M.; Dong, J.; Meijer, M.; Janssen, L. J. M.; Lourenco, V. S.; van der Kant, R.; Cru
10.1101/2021.12.15.472643 — neuroscience — Posted on 2022-10-05
3802 Time-of-day effects on motor learning
Truong, C.; Ruffino, C.; Gaveau, J.; White, O.; Hilt, P.; Papaxanthis, C.
10.1101/2022.10.03.510578 — neuroscience — Posted on 2022-10-05
3805 Selective accumulation of matrix proteins inside of peroxisomal subdomains
Ast, J.; Bäcker, N.; Martorano, D.; Renike, C.; Stehlik, T.; Heimerl, T.; Taxis, C.; Bange, G.; Bölker, M.; Sandrock, B.; Schink, K.; Freitag, J.
10.1101/2022.10.02.510529 — cell biology — Posted on 2022-10-05
3806 Heterosynaptic Plasticity of the Visuo-auditory Projection Requires Cholecystokinin released from Entorhinal Cortex Afferents
Sun, W.; Wu, H.; Peng, Y.; Tang, P.; Zhao, M.; Zheng, C. X.; Feng, H.; Li, H.; Liang, Y.; Li, J.; Su, J.; Chen, X.; Hökfelt, T.; He, J.
10.1101/2022.10.04.510820 — neuroscience — Posted on 2022-10-05
3807 Dopamine regulates decision thresholds in human reinforcement learning.
Chakroun, K.; Wiehler, A.; Wagner, B.; Mathar, D.; Ganzer, F.; vanEimeren, T.; Sommer, T.; Peters, J.
10.1101/2022.09.29.509499 — neuroscience — Posted on 2022-10-05
3811 Dually targeted proteins regulate proximity between peroxisomes and partner organelles
Stehlik, T.; Bittner, E.; Lam, J.; Dimitrov, L.; Schöck, I.; Harberding, J.; Heymons, N.; Schuldiner, M.; Zalckvar, E.; Bölker, M.; Schekman, R.; Freitag, J.
10.1101/2022.07.29.501968 — cell biology — Posted on 2022-10-05
3813 A cnidarian phylogenomic tree fitted with hundreds of 18S leaves
DeBiasse, M.; Buckenmeyer, A.; Macrander, J.; Babonis, L.; Bentlage, B. S.; Cartwright, P.; Prada, C.; Reitzel, A. M.; Stampar, S.; Collins, A.; Daly, M.; Ryan, J. F.
10.1101/2022.10.03.510641 — evolutionary biology — Posted on 2022-10-05
3815 The indispensable soma of Cardiocondyla obscurior ants
Nino, L. M. J.; Suess, A.; Heinze, J.; Schultner, E.; Oettler, J.
10.1101/2022.10.02.510526 — evolutionary biology — Posted on 2022-10-05
3816 Site-Specific Knockdown of Microglia in the Locus Coeruleus Regulates Hypervigilant Responses to Social Stress in Female Rats
Pate, B. S.; Bouknight, S. J.; Harrington, E. N.; Mott, S. E.; Augenblick, L. M.; Smiley, C. E.; Morgan, C. G.; Calatayud, B. M.; Martines-Muniz, G. A.; Thayer, J. F.; Wood, S. K.
10.1101/2022.10.03.509934 — neuroscience — Posted on 2022-10-05
3818 Geometric constraints on human brain function
Pang, J. C.; Aquino, K. M.; Oldehinkel, M.; Robinson, P. A.; Fulcher, B. D.; Breakspear, M.; Fornito, A.
10.1101/2022.10.04.510897 — neuroscience — Posted on 2022-10-05
3821 Neotropical birds and mammals show divergent behaviour responses to human pressure
Negret, P. J.; Luskin, M. S.; Gomez-Valencia, B.; Diaz, A.; Romero, L. H.; Restrepo, A.; Zahringer, J.; Ochoa-Quintero, J. M.; Mendes, C.
10.1101/2022.09.22.509119 — ecology — Posted on 2022-10-05
3822 Reduction of embryonic E93 expression as a key factor for the evolution of insect metamorphosis
Fernandez-Nicolas, A.; Machaj, G.; Ventos-Alfonso, A.; Pagone, V.; Minemura, T.; Ohde, T.; Daimon, T.; Ylla, G.; Belles, X.
10.1101/2022.10.04.510826 — developmental biology — Posted on 2022-10-05
3824 Nuclear autophagy interactome unveils WSTF as a constitutive nuclear inhibitor of inflammation
Wang, Y.; Eapen, V. V.; Kournoutis, A.; Onorati, A.; Li, X.; Zhou, X.; Cetinbas, M.; Wang, L.; Liu, J.; Bretz, C.; Zhou, Z.; Ho Sui, S. J.; Saladi, S. V.; Sadreyev, R.; Adams, P. D.; Kingston, R. E.; Yue, Z.; Johansen, T.; Dou, Z.
10.1101/2022.10.04.510822 — cell biology — Posted on 2022-10-05
3827 Adaptation to spindle assembly checkpoint inhibition through the selection of specific aneuploidies
Adell, M. A. Y.; Klockner, T. C.; Hoefler, R.; Wallner, L.; Schmid, J.; Markovic, A.; Martyniak, A.; Campbell, C. S.
10.1101/2022.10.04.510607 — cell biology — Posted on 2022-10-05
3829 Piezo2 voltage-block regulates mechanical pain sensitivity
Sanchez-Carranza, O.; Chakrabarti, S.; Kuehnemund, J.; Schwaller, F.; Begay, V.; Lewin, G. R.
10.1101/2022.10.04.510762 — neuroscience — Posted on 2022-10-05
3832 An In Vivo Analysis of the Functional Motifs of DEAD-box RNA Helicase Me31B in Drosophila Fertility and Germline Development
Kara, E.; McCambridge, A. H.; Proffer, M.; Dilts, C.; Pumnea, B.; Eshak, J.; Smith, K. A.; Fielder, I.; Doyle, D. A.; Ortega, B. M.; Mukatash, Y.; Malik, N.; Mohammed, A. R.; Govani, D.; Niepielko, M. G.; Gao, M.
10.1101/2022.10.04.510704 — developmental biology — Posted on 2022-10-05
3835 Generating fast-twitch myotubes in vitro using an optogenetic-based, quantitative contractility assay
Hennig, K.; Hardman, D.; Barata, D.; Martins, I. I.; Bernabeu, M. O.; Gomes, E. R.; Roman, W.
10.1101/2022.10.04.510824 — cell biology — Posted on 2022-10-05
3837 A novel micro-ECoG recording method for recording multisensory neural activity from the parietal to temporal cortexes in mice
Setogawa, S.; Kanda, R.; Tada, S.; Saitoh, Y.; Ishikawa, M.; Nakada, S.; Seki, F.; Hikishima, K.; Matsumoto, H.; Mizuseki, K.; Fukayama, O.; Osanai, M.; Sekiguchi, H.; Ohkawa, N.
10.1101/2022.10.01.510247 — neuroscience — Posted on 2022-10-05
3838 Carm1 regulates the speed of C/EBPa-induced transdifferentiation by a cofactor stealing mechanism
Garcia, G. T.; Kowenz-Leutz, E.; Tian, T. V.; Klonizakis, A.; Lerner, J.; De Andres-Aguayo, L.; Berenguer, C.; Carmona, M. P.; Casadesus, M. V.; Bulteau, R.; Francesconi, M.; Peiro, S.; Zaret, K. S.; Leutz, A.; Graf, T.
10.1101/2022.10.03.510647 — cell biology — Posted on 2022-10-04
3839 A membrane integral methyltransferase catalysing N-terminal histidine methylation of lytic polysaccharide monooxygenases
Batth, T. S.; Simonsen, J. L.; Rollan, C. H.; Brander, S.; Morth, J. P.; Johansen, K. S.; Norholm, M. H. H.; Hoof, J. B.; Olsen, J. V.
10.1101/2022.10.03.510680 — molecular biology — Posted on 2022-10-04
3840 Myelin-reactive B cells exacerbate the severity of CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner.
Fazazi, M. R.; Doss, P. M. I. A.; Pereira, R.; Fudge, N.; Regmi, A.; Akbar, I.; Yeola, A. P.; Mailhot, B.; Baillargeon, J.; Grenier, P.; Bertrand, N.; Lacroix, S.; Moore, C. S.; Rojas, O. L.; Rangachari, M.
10.1101/721696 — immunology — Posted on 2022-10-04
3841 CASK and FARP localize two classes of post-synaptic ACh receptors thereby promoting cholinergic transmission
Li, L.; Liu, H.; Qian, K.-Y.; Nurrish, S.; Zeng, X.-T.; Zeng, W.-X.; Wang, J.; Kaplan, J. M.; Tong, X.-J.; Hu, Z.
10.1101/2022.04.22.489135 — neuroscience — Posted on 2022-10-04
3842 Distinct hyperactive RAS/MAPK alleles converge on common GABAergic interneuron core programs
Knowles, S. J.; Stafford, A. M.; Zaman, T.; Angara, K.; Williams, M. R.; Newbern, J. M.; Vogt, D.
10.1101/2022.08.04.502867 — neuroscience — Posted on 2022-10-04
3844 Metabolic switch in the aging astrocyte supported via integrative approach comprising network and transcriptome analyses
Acevedo, A.; Torres, F.; Kiwi, M.; Baeza-Lehnert, F.; Barros, L. F.; Lee-Liu, D.; Gonzalez-Billault, C.
10.1101/2022.01.31.478210 — neuroscience — Posted on 2022-10-04
3845 Nutrigenomic Regulation of Sensory Plasticity
Sung, H.; Vaziri, A.; Wilinski, D.; Woerner, R.; Freddolino, P.; DUS, M.
10.1101/2021.12.17.473205 — neuroscience — Posted on 2022-10-04
3847 Engineered bacteria detect tumor DNA
Cooper, R. M.; Wright, J. A.; Ng, J. Q.; Goyne, J. M.; Suzuki, N.; Lee, Y. K.; Ichinose, M.; Radford, G.; Ryan, F.; Kumar, S.; Thomas, E. M.; Vrbanac, L.; Knight, R.; Woods, S. L.; Worthley, D. L.; Hasty, J.
10.1101/2021.09.10.459858 — synthetic biology — Posted on 2022-10-04
3851 A systematic method for detecting abnormal mRNA splicing and assessing its clinical impact in individuals undergoing genetic testing for hereditary cancer syndromes
Kamps-Hughes, N.; Carlton, V.; Fresard, L.; Osazuwa, S.; Starks, E.; Vincent, J. J.; Albritton, S.; Nussbaum, R. L.; Nykamp, K.
10.1101/2022.07.12.499782 — genetics — Posted on 2022-10-04
3853 Evolutionary history of Euteliidae (Lepidoptera, Noctuoidea)
Zahiri, R.; Holloway, J. D.; Rota, J.; Schmidt, C.; Pellinen, M. J.; Kitching, I. J.; Miller, S. E.; Wahlberg, N.
10.1101/2022.09.26.508383 — evolutionary biology — Posted on 2022-10-04
3855 Enteroendocrine cells protect the stem cell niche by regulating crypt metabolism in response to nutrients
McCauley, H. A.; Riedman, A. M.; Enriquez, J. R.; Zhang, X.; Watanabe-Chailland, M.; Sanchez, J. G.; Kechele, D. O.; Paul, E. F.; Riley, K.; Burger, C.; Lang, R. A.; Wells, J. M.
10.1101/2022.10.01.508931 — cell biology — Posted on 2022-10-04
3856 Atypical peripheral actin band formation via overactivation of RhoA and Non-muscle myosin II in Mitofusin 2 deficient cells
Wang, Y.; Troughton, L. D.; Xu, F.; Chatterjee, A.; Zhao, H.; Cifuentes, L. P.; Wagner, R. B.; Chen, J.; Kuang, S.; Suter, D. M.; Yuan, C.; Chan, D.; Huang, F.; Oakes, P. W.; Deng, Q.
10.1101/2022.10.03.510661 — cell biology — Posted on 2022-10-04
3857 Recycling limits the lifetime of actin turnover
Colin, A.; Kotila, T.; Guerin, C.; Orhant-Prioux, M.; Vianay, B.; Mogilner, A.; Lappalainen, P.; Thery, M.; Blanchoin, L.
10.1101/2022.09.30.510257 — cell biology — Posted on 2022-10-04
3860 Genome polarisation for detecting barriers to geneflow
Baird, S. J. E.; Petruzela, J.; Jaron, I.; Skrabanek, P.; Martinkova, N.
10.1101/2022.03.24.485605 — bioinformatics — Posted on 2022-10-04
3862 Nanoscale Friction of Biomimetic Hair Surfaces
Weiand, E.; Ewen, J. P.; Roiter, Y.; Koenig, P. H.; Page, S. H.; Rodriquez-Ropero, F.; Angioletti-Uberti, S.; Dini, D.
10.1101/2022.09.29.510078 — biochemistry — Posted on 2022-10-04
3863 142 telomere-to-telomere assemblies reveal the genome structural landscape in Saccharomyces cerevisiae
O'Donnell, S.; Yue, J.-X.; Abou Saada, O.; Agier, N.; Caradec, C.; Cokelaer, T.; De Chiara, M.; Delmas, S.; Dutreux, F.; Fournier, T.; Friedrich, A.; Kornobis, E.; Li, J.; Miao, Z.; Tattini, L.; Schacherer, J.; Liti, G.; Fischer, G.
10.1101/2022.10.04.510633 — genomics — Posted on 2022-10-04
3864 Megakaryocyte and erythroblast DNA in plasma and platelets
Moss, J.; Ben-Ami, R.; Shai, E.; Kalish, Y.; Klochendler, A.; Cann, G.; Glaser, B.; Arad, A.; Shemer, R.; Dor, Y.
10.1101/2022.10.03.510502 — genomics — Posted on 2022-10-04
3865 Single nucleus multiomics identifies ZEB1 and MAFB as candidate regulators of Alzheimer's disease-specific cis regulatory elements.
Anderson, A. G.; Rogers, B. B.; Loupe, J. M.; Rodriguez-Nunez, I.; Roberts, S. C.; White, L. M.; Brazell, J. N.; Bunney, W. E.; Bunney, B. G.; Watson, S.; Cochran, J. N.; Myers, R. M.; Rizzardi, L. F.
10.1101/2022.10.04.510636 — genomics — Posted on 2022-10-04
3869 EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling
Randzavola, L. O.; Mortimer, P. M.; Garside, E. C.; Dufficy, E. R.; Schejtman, A.; Roumelioti, G.; Yu, L.; Pardo, M.; Spirohn, K.; Tolley, C.; Brandt, C.; Harcourt, K.; Nichols, E.; Nahorski, M.; Woods, G.; Williamson, J. C.; Suresh, S.; Sowerby, J. M.; Matsumoto, M.; Santos, C. X. C.; Kiar, C. S.; Mukhopadhyay, S.; Rae, W. M.; Dougan, G.; Grainger, J. R.; Lehner, P. J.; Calderwood, M.; Chaudhary, J. S.; Clare, S.; Speak, A. O.; Santilli, G.; Bateman, A.; Smith, K. G. C.; Magnani, F.; Thomas, D. C.
10.1101/2021.09.14.460103 — immunology — Posted on 2022-10-04
3870 Do place cells dream of deceptive moves in a signaling game?
Fenton, A. A.; Hurtado, J. R.; Broek, J. A. C.; PARK, E. H.; Mishra, B.
10.1101/2022.01.30.478398 — neuroscience — Posted on 2022-10-04
3876 Structure of human phagocyte NADPH oxidase in the resting state
Liu, R.; Song, K.; Wu, J.-X.; Geng, X.-P.; Zheng, L.; Gao, X.; Peng, H.; Chen, L.
10.1101/2022.10.04.510768 — biochemistry — Posted on 2022-10-04
3877 Rheo-2DIR spectroscopy reveals strain-induced hydrogen-bond redistribution in polyurethane
Giubertoni, G.; Hilbers, M.; Groen, H.; Van Der Weide, A.; Bonn, D.; Woutersen, S.
10.1101/2022.10.04.510759 — biochemistry — Posted on 2022-10-04
3878 The genome-wide mutational consequences of DNA hypomethylation
Besselink, N.; Keijer, J.; Vermeulen, C.; Boymans, S.; de Ridder, J.; van Hoeck, A.; Cuppen, E.; Kuijk, E.
10.1101/2022.10.04.510776 — genomics — Posted on 2022-10-04
3879 In-silico enrichment of bacterial plasmids by chromosomal depletion using nanopore adaptive sampling
Ulrich, J.-U.; Epping, L.; Pilz, T.; Walther, B.; Stingl, K.; Semmler, T.; Renard, B. Y.
10.1101/2022.10.03.510741 — genomics — Posted on 2022-10-04
3880 Emerging variants of canine enteric coronavirus associated with seasonal outbreaks of severe canine gastroenteric disease
Cunningham-Oakes, E.; Pilgrim, J.; Darby, A. C.; Appleton, C.; Jewell, C.; Rowlingson, B.; Cuartero, C. T.; Newton, R.; Sanchez-Vizcaino, F.; Fins, I. S.; Brant, B.; Smith, S.; Penrince-Randal, R.; Clegg, S. R.; Roberts, A. P.; Millson, S. H.; Pinchbeck, G. L.; Noble, P.-J. M.; Radford, A. D.
10.1101/2022.10.03.510536 — genomics — Posted on 2022-10-04
3881 On the origins of phenotypic parallelism in benthic and limnetic stickleback
Dean, L. L.; Magalhaes, I. S.; D'Agostino, D.; Hohenlohe, P. A.; MacColl, A. D.
10.1101/2022.10.02.510516 — evolutionary biology — Posted on 2022-10-04
3884 Evaluation of K-Ras4B dimer interfaces and the role of Raf effectors
Chatzigoulas, A.; Andreadelis, I.; Doerr, S.; Lamprakis, C.; Theodoropoulou, A.; Manchester, J.; Velez-Vega, C.; Duca, J. S.; Cournia, Z.
10.1101/2022.10.04.510804 — molecular biology — Posted on 2022-10-04
3886 Molecular basis of the TRAP complex function in ER protein biogenesis
Jaskolowski, M.; Jomaa, A.; Gamerdinger, M.; Shrestha, S.; Leibundgut, M.; Deuerling, E.; Ban, N.
10.1101/2022.10.04.510795 — molecular biology — Posted on 2022-10-04
3891 MarR-Dependent Transcriptional Regulation of mmpSL5 Induces Ethionamide Resistance in Mycobacterium abscessus
Rodriguez, R.; Campbell-Kruger, N.; Gonzalez Camba, J.; Berude, J.; Fetterman, R.; Stanley, S.
10.1101/2022.10.03.510743 — microbiology — Posted on 2022-10-04
3892 Modelling the gastrointestinal carriage of Klebsiella pneumoniae infections.
Calderon-Gonzalez, R.; Lee, A.; Lopez Campos, G.; Hancock, S. J.; Sa-Pessoa, J.; Dumigan, A.; McMullan, R.; Campbell, E. L.; Bengoechea, J. A.
10.1101/2022.10.03.510744 — microbiology — Posted on 2022-10-04
3894 Comparative genomics and transcriptomic response to root exudates of six rice root-associated Burkholderia sensu lato species
Wallner, A.; Klonowska, A.; Guigard, L.; Rimbault, I.; Ngonkeu, E. L.; Nguyen, P. V.; Bena, G.; Moulin, L.
10.1101/2022.10.04.510755 — microbiology — Posted on 2022-10-04
3897 Irx1 and Irx2 play dose-dependent cooperative functions in mammalian development
Sheybani-Deloui, S.; Xu, L.; Hu, L.; Yuan, Q.; Son, J. E.; Son, J. E.; Kim, K.-H.; Liu, W.; Mo, R.; Zhang, X.; Chi, L.; Delgado Olguin, P.; Hui, C.-C.
10.1101/2022.10.03.510739 — developmental biology — Posted on 2022-10-04
3898 Connectomics of the Octopus vulgaris vertical lobe provides insight into conserved and novel principles of a memory acquisition network
Bidel, F.; Meirovitch, Y.; Schalek, R. L.; Lu, X.; Pavarino, E. C.; Yang, F.; Peleg, A.; Wu, Y.; Shomrat, T.; Berger, D. R.; Shaked, A.; Lichtman, J. W.; Hochner, B.
10.1101/2022.10.03.510303 — neuroscience — Posted on 2022-10-04
3899 Vascular tortuosity quantification as an outcome metric of the oxygen-induced retinopathy model of ischemic retinopathy
Marra, K. V.; Chen, J. S.; Robles-Holmes, H. K.; Miller, J.; Wei, G.; Ideguchi, Y.; Ly, K. B.; Prenner, S.; Erdogmus, D.; Ferrara, N.; Campbell, J. P.; Friedlander, M.; Nudleman, E.
10.1101/2022.10.02.510568 — neuroscience — Posted on 2022-10-04
3901 Dynein-mediated trafficking and degradation of nephrin in diabetic podocytopathy
Sun, H.; Weidner, J.; Allamargot, C.; Piper, R. C.; Misurac, J.; Nester, C.
10.1101/2022.10.01.510475 — physiology — Posted on 2022-10-04
3903 Time-of-day effects on motor learning
Truong, C.; Ruffino, C.; Gaveau, J.; Hilt, P.; White, O.; Papaxanthis, C.
10.1101/2022.10.03.510578 — neuroscience — Posted on 2022-10-04
3904 Validating MEG source imaging of resting state oscillatory patterns with an intracranial EEG atlas
Afnan, J.; von Ellenrieder, N.; Lina, J.-M.; Pellegrino, G.; Arcara, G.; Cai, Z.; Hedrich, T.; Abdallah, C.; Khajehpour, H.; Frauscher, B.; Gotman, J.; Grova, C.
10.1101/2022.10.03.510665 — neuroscience — Posted on 2022-10-04
3905 Highly synchronized cortical circuit dynamics mediate spontaneous pain
Ding, W.; Fischer, L.; Chen, Q.; Li, Z.; Yang, L.; You, Z.; Hu, K.; Wu, X.; Zhou, X.; Chao, W.; Hu, P.; Dagnew, T. M.; DuBreuil, D.; Wang, S.; Xia, S.; Bao, C.; Zhu, S.; Chen, L.; Wang, C.; Wainger, B. M.; Jin, P.; Mao, J.; Feng, G.; Harnett, M.; Shen, S.
10.1101/2022.10.04.510722 — neuroscience — Posted on 2022-10-04
3907 Epigenetically distinct synaptic architecture in clonal compartments in the teleostean dorsal pallium
Isoe, Y.; Nakamura, R.; Nonaka, S.; Kamei, Y.; Okuyama, T.; Yamamoto, N.; Takeuchi, H.; Takeda, H.
10.1101/2022.10.01.510385 — neuroscience — Posted on 2022-10-04
3909 A galanin-positive population of lumbar spinal cord neurons modulates sexual behavior and arousal
Lenschow, C.; Mendes, A. P.; Ferreira, L.; Lacoste, B.; Quilgars, C.; Bertrand, S. S.; Lima, S. Q.
10.1101/2022.10.04.510783 — neuroscience — Posted on 2022-10-04
3913 Insulin receptor substrate 4 deficiency mediates the insulin effect on the epithelial magnesium channel TRPM6 and causes hypomagnesemia
Zhang, J.; An, S. W.; Neelam, S.; Bhatta, A.; Nie, M.; Duran, C.; Bal, M.; Latta, F.; Hou, J. S.; Otto, J. J.; Kozlitina, J.; Lemoff, A.; Hoenderop, J.; Baum, M.; Wolf, M. T.
10.1101/2022.10.01.510479 — physiology — Posted on 2022-10-04
3914 TCRi: Information theoretic metrics for single cell RNA and TCR sequencing in cancer
Ceglia, N.; Sethna, Z. M.; Elhanati, Y.; Burman, B.; Chow, A.; Zamarin, D.; DeWolf, S.; Shahid, S.; Bojilova, V.; Rusk, N.; Balachandran, V. P.; McPherson, A.; Shah, S. P.; Greenbaum, B. D.
10.1101/2022.10.01.510457 — bioinformatics — Posted on 2022-10-04
3925 Systems-level investigation of mucopolysaccharidosis IIIA identifies deficient synaptic activity as a key driver of disease progression
Douek, A. M.; Salavaty, A.; Kreuder, F.; Stamatis, S.-A.; Steele, J. R.; Hanchapola, I.; Shah, A. D.; Schittenhelm, R. B.; Ramialison, M.; Currie, P. D.; Kaslin, J.
10.1101/2022.10.03.510585 — neuroscience — Posted on 2022-10-04
3927 Mechanisms of adjustments to different types of uncertainty in the reward environment across mice and monkeys
Hyung Woo, J.; Aguirre, C. G.; Bari, B. A.; Tsutsui, K.-I.; Grabenhorst, F.; Cohen, J. Y.; Schultz, W.; Izquierdo, A.; Soltani, A.
10.1101/2022.10.01.510477 — neuroscience — Posted on 2022-10-04
3928 Visual evoked potentials as an early-stage biomarker in the rTg4510 tauopathy mouse model
Parka, A.; Volbracht, C.; Hall, B.; Bastlund, J. F.; Nedergaard, M.; Laursen, B.; Botta, P.; Sotty, F.
10.1101/2022.10.03.510063 — neuroscience — Posted on 2022-10-04
3929 Pharmacologic Inhibition of DYRK1A Results in MYC Hyperactivation and ERK Hyperphosphorylation rendering KMT2A-R ALL Cells Sensitive to BCL2 Inhibition
Hurtz, C.; Ayyadevara, V. S. S. A.; Wertheim, G.; Chukinas, J.; Loftus, J. P.; Lee, S. J.; Kumar, A.; Bhansali, R. S.; Swaminathan, S.; Geng, H.; Milne, T.; Hua, X.; Bernt, K. M.; Besson, T.; Shi, J.; Crispino, J. D.; Carroll, M.; Tasian, S. K.
10.1101/2022.10.02.510349 — cancer biology — Posted on 2022-10-04
3930 Intracellular FUS protein accumulation leads to cytoskeletal, organelle and cellular homeostasis perturbations
Chung, C. W.; Zhou, A. J.; Mela, I.; Stephens, A. D.; Miyashita, A.; St George-Hyslop, P. H.; Kaminski, C. F.; Knowles, T.; Kaminski Schierle, G. S.
10.1101/2022.10.04.510756 — biophysics — Posted on 2022-10-04
3933 Arterial cells support the development of human hematopoietic progenitors in vitro via secretion of IGFBP2.
Petazzi, P.; Ventura, T.; May, A.; Luongo, F. P.; Taylor, H. A.; Romano, N.; Forrester, L. M.; Menendez, P.; Fidanza, A.
10.1101/2022.10.04.510611 — developmental biology — Posted on 2022-10-04
3934 In vivo generation of heart and vascular system by blastocyst complementation
Coppiello, G.; Barlabe, P.; Moya-Jodar, M.; Abizanda, G.; Barreda, C.; Iglesias, E.; Linares, J.; Arellano-Viera, E.; Ruiz-Villalba, A.; Larequi, E.; Carvajal-Vergara, X.; Pelacho, B.; Prosper, F.; Aranguren, X. L.
10.1101/2022.10.04.510637 — cell biology — Posted on 2022-10-04
3935 Raman microspectroscopy reveals unsaturation heterogeneity at the lipid droplet level and validates an in vitro model of bone marrow adipocyte subtypes
Tratwal, J.; Falgayrac, G.; Berthaume, N.; Bataclan, C.; Tavakol, D. N.; Campos, V.; Duponchel, L.; Daley, G. Q.; Penel, G.; Chauveau, C.; Naveiras, O.
10.1101/2022.10.03.510634 — cell biology — Posted on 2022-10-04
3936 Empagliflozin reduces renal lipotoxicity in experimental Alport syndrome
Ge, M.; Molina, J.; Kim, J. J.; Mallela, S. K.; Ahmad, A.; Varona Santos, J.; Al-Ali, H.; Mitrofanova, A.; Sharma, K.; Fontanesi, F.; Merscher, S.; Fornoni, A.
10.1101/2022.10.04.510832 — cell biology — Posted on 2022-10-04
3937 A neonatal mouse model characterizes transmissibility of SARS-CoV-2 variants and reveals a role for ORF8
Rodriguez-Rodriguez, B. A.; Ciabattoni, G.; Valero-Jimenez, A. M.; Crosse, K. M.; Schinlever, A.; Rodriguez-Galvan, J. J.; Duerr, R.; McGrath, M.; Desvignes, L.; Frieman, M.; Ortigoza, M. B.; Dittmann, M.
10.1101/2022.10.04.510658 — microbiology — Posted on 2022-10-04
3938 Distinct phenotype of SARS-CoV-2 Omicron BA.1 in human primary cells but no increased host range in cell lines of putative mammalian reservoir species
Essaidi-Laziosi, M.; Perez Rodriguez, F. J.; Alvarez, C.; Sattonnet-Roche, P.; Torriani, G.; Bekliz, M.; Adea, K.; Lenk, M.; Preiser, W.; Suliman, T.; Muller, M. A.; Drosten, C.; Kaiser, L.; Eckerle, I.
10.1101/2022.10.04.510352 — microbiology — Posted on 2022-10-04
3939 SARS-CoV-2 ORF3c impairs mitochondrial respiratory metabolism, oxidative stress and autophagic flow
Mozzi, A.; Oldani, M.; Forcella, M. E.; Vantaggiato, C.; Cappelletti, G.; Pontremoli, C.; Valenti, F.; Forni, D.; Biasin, M.; Sironi, M.; Fusi, P.; Cagliani, R.
10.1101/2022.10.04.510754 — microbiology — Posted on 2022-10-04
3940 Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution
Cao, Y.; Jian, F.; Wang, J.; Yu, Y.; Song, W.; Yisimayi, A.; Wang, J.; An, R.; Zhang, N.; Wang, Y.; Wang, P.; Zhao, L.; Sun, H.; Yu, L.; Yang, S.; Niu, X.; Xiao, T.; Gu, Q.; Shao, F.; Hao, X.; Xu, Y.; Jin, R.; Wang, Y.; Xie, X. S.
10.1101/2022.09.15.507787 — immunology — Posted on 2022-10-04
3942 Relevance of the viral Spike protein/cellular Estrogen Receptor-α interaction for endothelial-based coagulopathy induced by SARS-CoV-2
Barbieri, S. S.; Cattani, F.; Sandrini, L.; Grillo, M. M.; Talarico, C.; Iaconis, D.; Lione, L.; Salvatori, E.; Amadio, P.; Garoffolo, G.; Maffei, M.; Galli, F.; Beccari, A. R.; Marra, E.; Zoppi, M.; Michaelides, M.; Roscilli, G.; Aurisicchio, L.; Bertini, R.; Allegretti, M.; Pesce, M.
10.1101/2022.10.04.510657 — cell biology — Posted on 2022-10-04
3944 O-Linked Sialoglycans Modulate the Proteolysis of SARS-CoV-2 Spike and Likely Contribute to the Mutational Trajectory in Variants of Concern
Gonzalez-Rodriguez, E.; Zol-Hanlon, M.; Bineva-Todd, G.; Marchesi, A.; Skehel, M.; Mahoney, K.; Roustan, C.; Borg, A.; Di Vagno, L.; Kjaer, S.; Wrobel, A. G.; Benton, D. J.; Nawrath, P.; Flitsch, S. L.; Joshi, D.; Gonzalez-Ramirez, A. M.; Wilkinson, K. A.; Wilkinson, R. J.; Wall, E. C.; Hurtado-Guerrero, R.; Malaker, S. A.; Schumann, B.
10.1101/2022.09.15.508093 — cell biology — Posted on 2022-10-04
3945 A novel micro-ECoG recording method for recording multisensory neural activity from the parietal to temporal cortexes in mice
Setogawa, S.; Kanda, R.; Tada, S.; Saitoh, Y.; Ishikawa, M.; Nakada, S.; Seki, F.; Hikishima, K.; Matsumoto, H.; Mizuseki, K.; Fukayama, O.; Osanai, M.; Sekiguchi, H.; Ohkawa, N.
10.1101/2022.10.01.510247 — neuroscience — Posted on 2022-10-04
3946 Atypical peripheral actin band formation via overactivation of RhoA and Non-muscle myosin II in Mitofusin 2 deficient cells
Wang, Y.; Troughton, L. D.; Xu, F.; Chatterjee, A.; Zhao, H.; Cifuentes, L. P.; Wagner, R. B.; Chen, J.; Kuang, S.; Suter, D. M.; Yuan, C.; Chan, D.; Huang, F.; Oakes, P. W.; Deng, Q.
10.1101/2022.10.03.510661 — cell biology — Posted on 2022-10-04
3947 Modelling Membrane Reshaping by Staged Polymerization of ESCRT-III Filaments
Jiang, X.; Harker-Kirschneck, L.; Vanhille Campos, C.; Pfitzner, A.-K.; Lominadze, E.; Roux, A.; Baum, B.; Saric, A.
10.1101/2022.10.03.508498 — biophysics — Posted on 2022-10-04
3948 Phylogeographic breaks and how to find them: Separating vicariance from isolation by distance in a lizard with restricted dispersal
Rancilhac, L.; Miralles, A.; Geniez, P.; Mendez-Aranda, D.; Beddek, M.; Brito, J. C.; Leblois, R.; Crochet, P.-A.
10.1101/2022.09.30.510256 — evolutionary biology — Posted on 2022-10-04
3952 Carm1 regulates the speed of C/EBPa-induced transdifferentiation by a cofactor stealing mechanism
Garcia, G. T.; Kowenz-Leutz, E.; Tian, T. V.; Klonizakis, A.; Lerner, J.; De Andres-Aguayo, L.; Berenguer, C.; Carmona, M. P.; Casadesus, M. V.; Bulteau, R.; Francesconi, M.; Leutz, A.; Zaret, K. S.; Zaret, K. S.; Peiro, S.
10.1101/2022.10.03.510647 — cell biology — Posted on 2022-10-04
3953 Midbody proteins display distinct temporal dynamics during cytokinesis
Halcrow, E. F. J.; Mazza, R.; Diversi, A.; Enright, A.; D'Avino, P. P.
10.1101/2022.10.03.510602 — cell biology — Posted on 2022-10-04
3955 AKIR-1 Regulates Proteasome Localization and Function in Caenorhabditis elegans
Pispa, J.; Mikkonen, E.; Arpalahti, L.; Congyu, J.; Martinez-Fernandez, C.; Ceron, J.; Holmberg-Still, C.
10.1101/2022.10.03.510264 — cell biology — Posted on 2022-10-04
3956 The cellular states and fates of shed intestinal cells
Bahar Halpern, K.; Biram, A.; Egozi, A.; Korem Kohanim, Y.; Shulman, Z.; Itzkovitz, S.
10.1101/2022.10.03.510592 — cell biology — Posted on 2022-10-04
3960 Vimentin supports directional cell migration by controlling focal adhesions
Eriksson, J. E.; Venu, A. P.; Modi, M.; Aryal, U.; Tcarenkova, E.; Jiu, Y.; Jacquemet, G.; Minin, A.; Cheng, F. E.
10.1101/2022.10.02.510295 — cell biology — Posted on 2022-10-04
3962 Minor intron containing genes: Achilles' heel of viruses?
Wuchty, S.; White, A. K.; Olthof, A. M.; Drake, K.; Hume, A. J.; Olejnik, J.; Muehlberger, E.; Aguiar-Pulido, V.; Kanadia, R. N.
10.1101/2022.09.30.510319 — systems biology — Posted on 2022-10-04
3963 Structural basis for activation of DNMT1
Kikuchi, A.; Onoda, H.; Yamaguchi, K.; Kori, S.; Matsuzawa, S.; Chiba, Y.; Tanimoto, S.; Yoshimi, S.; Sato, H.; Yamagata, A.; Shirouzu, M.; Adachi, N.; Sharif, J.; Koseki, H.; Nishiyama, A.; Nakanishi, M.; Defossez, P. A.; Arita, K.
10.1101/2022.06.16.496385 — biochemistry — Posted on 2022-10-04
3964 Antisense oligonucleotides targeting exon 11 are able to partially rescue the Neurofibromatosis Type 2 phenotype in vitro
Catasus, N.; Rosas, I.; Bonache, S.; Negro, A.; Torres-Martin, M.; Plana, A.; Salvador, H.; Serra, E.; Blanco, I.; CASTELLANOS, E.
10.1101/2022.02.11.479859 — genetics — Posted on 2022-10-04
3968 High predation risk decimates survival during the reproduction season
Smolinsky, R.; Hiadlovska, Z.; Marsala, S.; Skrabanek, P.; Skrobanek, M.; Martinkova, N.
10.1101/2022.03.31.486539 — ecology — Posted on 2022-10-04
3969 Tissue libraries enable rapid determination of conditions that preserve antibody labeling in cleared mouse and human tissue
Zwang, T. J.; Bennett, R. E.; Lysandrou, M.; Woost, B.; Zhang, A.; Lieber, C. M.; Richardson, D. S.; Hyman, B. T.
10.1101/2022.05.25.493465 — cell biology — Posted on 2022-10-04
3971 Evolutionary and biomedical implications of sex differences in the primate brain transcriptome
DeCasien, A. R.; Chiou, K. L.; Testard, C.; Mercer, A.; Negron-Del Valle, J. E.; Surratt, S. E. B.; Gonzalez, O.; Stock, M. K.; Ruiz-Lambides, A. V.; Martinez, M. I.; Cayo Biobank Research Unit, ; Anton, S.; Walker, C. S.; Sallet, J.; Wilson, M. A.; Brent, L. J. N.; Montague, M. J. N.; Sherwood, C. C.; Platt, M. L.; Higham, J. P.; Snyder-Mackler, N.
10.1101/2022.10.03.510711 — neuroscience — Posted on 2022-10-04
3972 Sonic hedgehog-dependent recruitment of GABAergic interneurons into the developing visual thalamus
Somaiya, R. D.; Stebbins, K.; Gingrich, E. C.; Xie, H.; Campbell, J. N.; Garcia, A. D. R.; Fox, M.
10.1101/2022.02.22.481508 — neuroscience — Posted on 2022-10-04
3973 Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger
Hata, K.; Kobayashi, N.; Sugimura, K.; Qin, W.; Haxholli, D.; Chiba, Y.; Yoshimi, S.; Hayashi, G.; Onoda, H.; Ikegami, T.; Mulholland, C. B.; Nishiyama, A.; Nakanishi, M.; Leonhardt, H.; Konuma, T.; Arita, K.
10.1101/2022.06.14.496052 — biochemistry — Posted on 2022-10-04
3977 Cancer-associated SMARCAL1 loss-of-function mutations promote alternative lengthening of telomeres and tumorigenesis in telomerase-negative glioblastoma cells
Liu, H.; Xu, C.; Diplas, B. H.; Brown, A.; Strickland, L. M.; Ling, J.; McLendon, R. E.; Keir, S. T.; Ashley, D. M.; He, Y.; Waitkus, M. S.
10.1101/2022.09.19.507319 — cancer biology — Posted on 2022-10-03
3978 Targeting aggressive B-cell lymphomas through pharmacological activation of the mitochondrial protease OMA1
Schwarzer, A.; Oliveira, M.; Kleppa, M.-J.; Slattery, S. D.; Anantha, A.; Cooper, A.; Hannink, M.; Schambach, A.; Dorrie, A.; Kotlyarov, A.; Gaestel, M.; Hembrough, T.; Levine, J.; Luther, M.; Stocum, M.; Stiles, L.; Weinstock, D.; Liesa, M.; Kostura, M. J.
10.1101/2022.06.12.495213 — cancer biology — Posted on 2022-10-03
3983 Single-component multilayered self-assembling protein nanoparticles presenting glycan-trimmed uncleaved prefusion optimized envelope trimers as HIV-1 vaccine candidates
Zhang, Y.-N.; Paynter, J.; Antanasijevic, A.; Allen, J. D.; Eldad, M.; Lee, Y.-Z.; Copps, J.; Newby, M.; He, L.; Chavez, D.; Frost, P.; Goodroe, A. E.; Dutton, J. W.; Lanford, R.; Chen, C.; Wilson, I. A.; Crispin, M.; Ward, A.; Zhu, J.
10.1101/2022.07.01.498503 — microbiology — Posted on 2022-10-03
3985 Effects of variability in manually contoured spinal cord masks on fMRI co-registration and interpretation
Hoggarth, M. A.; Wang, M. C.; Hemmerling, K. J.; Vigotsky, A. D.; Smith, Z. A.; Parrish, T. B.; Weber, K. A.; Bright, M. G.
10.1101/2022.03.25.485810 — neuroscience — Posted on 2022-10-03
3989 Subtilases turn on Pectin Methylesterase activity for a robust apoplastic immunity against pathogens
Coculo, D.; Del Corpo, D.; Martinez, M. O.; Vera, P.; Piro, G.; De Caroli, M.; Lionetti, V.
10.1101/2022.07.28.501549 — plant biology — Posted on 2022-10-03
3994 Expanded FLP toolbox for spatiotemporal protein degradation and transcriptomic profiling in C. elegans
Fragoso-Luna, A.; Romero-Bueno, R.; Eibl, M.; Ayuso, C.; Munoz-Jimenez, C.; Benes, V.; Cases, I.; Askjaer, P.
10.1101/2021.12.21.473632 — genetics — Posted on 2022-10-03
3996 Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues
Pearson, G. L.; Walker, E. M.; Lawlor, N.; Lietzke, A.; Sidarala, V.; Zhu, J.; Stromer, T.; Reck, E. C.; Li, J.; Renberg, A.; Mohamed, K.; Parekh, V. S.; Zhang, I. X.; Thompson, B.; Zhang, D.; Ware, S. A.; Haataja, L.; Parker, S. C. J.; Arvan, P.; Yin, L.; Kaufman, B. A.; Satin, L. S.; Sussel, L.; Stitzel, M. L.; Soleimanpour, S. A.
10.1101/2022.08.02.502357 — cell biology — Posted on 2022-10-03
3997 Achieving quantitative and accurate measurement of the human gut microbiome
Maghini, D. G.; Dvorak, M.; Dahlen, A.; Roos, M.; Kuersten, S.; Bhatt, A. S.
10.1101/2022.09.28.509972 — microbiology — Posted on 2022-10-03
3998 A small molecule that inhibits the evolution of antibiotic resistance
Johnson, A. E.; Bracey, H.; Viera, A. J. H.; Carvajal-Garcia, J.; Simsek, E. N.; Kim, K.; Merrikh, H.
10.1101/2022.09.26.509600 — microbiology — Posted on 2022-10-03
3999 The population-level impact of Enterococcus faecalis genetics on intestinal colonisation and extraintestinal infection
Chaguza, C.; Pöntinen, A. K.; Top, J.; Arredondo-Alonso, S.; Freitas, A. R.; Novais, C.; Torres, C.; Bentley, S. D.; Peixe, L.; Coque, T. M.; Willems, R. J. L.; Corander, J.
10.1101/2022.09.26.509451 — microbiology — Posted on 2022-10-03
4001 The PTEX pore component EXP2 is important for intrahepatic development during the Plasmodium liver stage
Hussain, T.; Linera-Gonzalez, J.; Beck, J. M.; Fierro, M. A.; Mair, G. R.; Smith, R. C.; Beck, J. R.
10.1101/2022.10.02.510306 — microbiology — Posted on 2022-10-03
4003 Inhibition of CHK2 dependent DNA damage response suppresses Zika virus infection through a STING dependent mechanism
Ma, H.; Li, C.; Wang, Y.; Valore, E. V.; Trisal, M.; Sai-yin Hui, H.; Hakimpour, P.; Bowen, J. R.; Mak, T. W.; Suthar, M. S.; Pulendran, B.
10.1101/2022.10.03.510601 — immunology — Posted on 2022-10-03
4004 Chromatin access regulates the formation of Muller glia-derived progenitor cells in the retina
Campbell, W. J.; El-Hodiri, H.; Torres, D.; Hawthorn, E.; Kelly, L.; Volkov, L.; Akanonu, D.; Fischer, A. J.
10.1101/2022.06.23.497349 — neuroscience — Posted on 2022-10-03
4005 Noradrenergic input from nucleus of the solitary tract regulates parabrachial activity in mice
Onwukwe, C.; Ji, Y.; Smith, J.; Laub, H.; Posa, L.; Keller, A.; Masri, R.; Cramer, N.
10.1101/2022.09.29.510103 — neuroscience — Posted on 2022-10-03
4006 Dynamic refinement of behavioral structure mediates dopamine-dependent credit assignment
Tang, J. C. Y.; Paixao, V.; Carvalho, F.; Silva, A.; Klaus, A.; Alves da Silva, J.; Costa, R. M.
10.1101/2022.09.22.507905 — neuroscience — Posted on 2022-10-03
4007 Kleptocytosis: A Novel Parasitic Strategy for Accelerated Reproduction via Host Protein Stealing in Varroa destructor
Ramsey, S. D.; Cook, S. C.; Gulbronson, C.; vanEngelsdorp, D.; Evans, J. D.; Posada-Florez, F.; Sonenshine, D.
10.1101/2022.09.30.509900 — zoology — Posted on 2022-10-03
4008 A Genome Scale Transcriptional Regulatory Model of the Human Placenta
Paquette, A. G.; Ahuna, K.; Hwang, Y. M.; Pearl, J.; Liao, H.; Shannon, P.; Kadam, L.; Lapehn, S.; Bucher, M.; Roper, R.; Funk, C. C.; MacDonald, J.; Bammler, T.; Baloni, P.; Brockway, H.; Mason, W. A.; Bush, N.; LeWinn, K. Z.; Karr, C. J.; Stamatoyannopoulos, J.; Muglia, L. J.; Jones, H. M.; Sadovsky, Y.; Myatt, L.; Sathyanarayana, S.; Price, N.; Environmental influences on Child Health Outcomes,
10.1101/2022.09.27.509541 — systems biology — Posted on 2022-10-03
4009 Cardiovascular Hemodynamics in Mice with Tumor Necrosis Factor Receptor - Associated Factor 2 Mediated Cytoprotection in the Heart
Marshall, A. G.; Neikirk, K.; Vue, Z.; Beasley, H. K.; Garza-Lopez, E.; Vang, L.; Barongan, T.; Evans, Z.; Crabtree, A.; Spencer, E.; Anudokem, J.; Parker, R.; Davis, J.; Stephens, D.; Damo, S.; Pham, T. T.; Gomez, J. A.; Exil, V.; Dai, D.-F.; Entman, M. L.; Taffet, G. E.; Hinton, A.; Reddy, A. K.
10.1101/2022.09.03.506447 — biophysics — Posted on 2022-10-03
4010 Genetically encoded non-canonical amino acids reveal asynchronous dark reversion of chromophore, backbone and side-chains in EL222
Chaudhari, A. S.; Chatterjee, A.; Domingos, C. A. O.; Andrikopoulos, P. C.; Liu, Y.; Andersson, I.; Schneider, B.; Lorenz-Fonfria, V. A.; Fuertes, G.
10.1101/2022.09.16.506679 — biophysics — Posted on 2022-10-03
4013 Human HelQ and DNA polymerase δ interact to halt DNA synthesis and stimulate DNA single-strand annealing
He, L.; Lever, R.; Cubbon, A.; Tehseen, M.; Nottingham, A. O.; Horton, A.; Betts, H.; Fisher, M.; Hamdan, S. M.; Soultanas, P.; Bolt, E. L.
10.1101/2022.10.02.510506 — biochemistry — Posted on 2022-10-03
4014 Decoupling of mRNA and protein expression in aging brains reveals the age-dependent adaptation of specific gene subsets
Khatir, I.; Brunet, M. A.; Meller, A.; Amiot, F.; Patel, T.; Lopez, J. A.; Guilloy, N.; Castonguay, A.; Husain, M. A.; St Germain, J.; Boisvert, F. M.; Plourde, M.; Roucou, X.; Laurent, B.
10.1101/2022.10.02.509373 — biochemistry — Posted on 2022-10-03
4015 Tuning aromatic contributions by site-specific encoding of fluorinated phenylalanine residues in bacterial and mammalian cells
Galles, G. D.; Infield, D. T.; Clark, C. J.; Hemshorn, M. L.; Manikandan, S.; Fazan, F. S.; Rasouli, A.; Tajkhorshid, E.; Galpin, J. D.; Cooley, R. B.; Mehl, R. A.; Ahern, C. A.
10.1101/2022.04.12.488046 — biochemistry — Posted on 2022-10-03
4016 Goldilocks and RNA: Where Mg2+ concentration is just right
Guth-Metzler, R.; Mohamed, A. M.; Cowan, E. T.; Henning, A.; Ito, C.; Frenkel-Pinter, M.; Wartell, R.; Glass, J. B.; Williams, L. D.
10.1101/2021.07.01.450745 — biochemistry — Posted on 2022-10-03
4019 Increased birth rank of homosexual males: disentangling the older brother effect and sexual antagonism hypothesis
Raymond, M.; Turek, D.; Durand, V.; Nila, S.; Suryobroto, B.; Vadez, J.; Barthes, J.; Apostolou, M.; Crochet, P.-A.
10.1101/2022.02.22.481477 — evolutionary biology — Posted on 2022-10-03
4020 Plasmid stability in fluctuating environments:population genetics of multi-copy plasmids
Miro Pina, V.; Hernandez-Beltran, J. C. R.; Siri-Jegousse, A.; Palau, S.; Pena-Miller, R.; Gonzalez-Casanova, A.
10.1101/2022.03.15.484385 — evolutionary biology — Posted on 2022-10-03
4022 Single cell evaluation of endocardial HAND2 gene regulatory networks reveals critical HAND2 dependent pathways impacting cardiac morphogenesis.
George, R. M.; Firulli, B. A.; Podicheti, R.; Rusch, D. B.; Mannion, B. J.; Pennacchio, L. A.; Osterwalder, M.; Firulli, A. B.
10.1101/2022.09.29.510167 — developmental biology — Posted on 2022-10-03
4023 Optimised whole-genome CRISPR interference screens identify ARID1A-dependent growth regulators in human induced pluripotent stem cells
Usluer, S.; Hallast, P.; Crepaldi, L.; Zhou, Y.; Urgo, K.; Dincer, C.; Su, J.; Noell, G.; Alasoo, K.; El Garwany, O.; Gerety, S.; Newman, B.; Dovey, O. M.; Parts, L.
10.1101/2022.10.03.510590 — cell biology — Posted on 2022-10-03
4024 Pitfalls in methods to study colocalization of nanoparticles in mouse macrophage lysosomes
Moreno-Echeverri, A. M.; Susnik, E.; Vanhecke, D.; Taladriz-Blanco, P.; Balog, S.; Petri-Fink, A.; Rothen-Rutishauser, B.
10.1101/2022.07.21.500664 — cell biology — Posted on 2022-10-03
4025 Molecular insights into the Darwin paradox of coral reefs from the sea anemone Aiptasia
Cui, G.; Konciute, M. K.; Ling, L.; Esau, L.; Raina, J.-B.; Han, B.; Salazar, O. R.; Presnell, J. S.; Radecker, N.; Zhong, H.; Menzies, J.; Cleves, P. A.; Liew, Y. J.; Krediet, C. J.; Sawiccy, V.; Cziesielski, M. J.; Guagliardo, P.; Bougoure, J.; Pernice, M.; Hirt, H.; Voolstra, C. R.; Weis, V. M.; Pringle, J. R.; Aranda, M.
10.1101/2022.10.02.510507 — molecular biology — Posted on 2022-10-03
4028 Large-scale phylogenomics of aquatic bacteria reveal molecular mechanisms for adaptation to salinity
Jurdzinski, K. T.; Mehrshad, M.; Delgado, L. F.; Deng, Z.; Bertilsson, S.; Andersson, A. A.
10.1101/2022.10.03.510577 — microbiology — Posted on 2022-10-03
4031 The origins of haplotype 58 (H58) Salmonella enterica serovar Typhi
Carey, M. E.; Nguyen Thi Nguyen, T.; Do Hoang Nhu, T.; Dyson, Z.; Pham, D. T.; Mylona, E.; Nair, S.; Chattaway, M.; Baker, S.
10.1101/2022.10.03.510628 — microbiology — Posted on 2022-10-03
4032 Volatile metabolites in lavage fluid are correlated to Valley fever disease severity in murine model lung infections
Keppler, E. A. H.; Van Dyke, M. C. C.; Mead, H. L.; Lake, D. F.; Magee, D. M.; Barker, B. M.; Bean, H. D.
10.1101/2022.10.02.510537 — microbiology — Posted on 2022-10-03
4034 Transcriptional profiling of zebrafish identifies host factors controlling susceptibility to Shigella flexneri
Torraca, V.; White, R.; Sealy, I. M.; Mazon-Moya, M.; Duggan, G.; Willis, A. R.; Busch-Nentwich, E.; Mostowy, S.
10.1101/2022.10.03.510593 — microbiology — Posted on 2022-10-03
4035 A conserved metabolic signature associated with response to fast-acting antimalarial agents
Simwela, N. V.; Guiguemde, A. W.; Straimer, J.; Regnault, C.; Yokokawa, F.; Taft, B.; Diagana, T. T.; Barrett, M. P.; Waters, A. P.
10.1101/2022.10.03.510714 — microbiology — Posted on 2022-10-03
4038 A call to rethink the cognitive benefits of physical exercise: An umbrella review of randomized controlled trials
Ciria, L. F.; Romn-Caballero, R.; Vadillo, M. A.; Holgado, D.; Luque-Casado, A.; Perakakis, P.; Sanabria, D.
10.1101/2022.02.15.480508 — neuroscience — Posted on 2022-10-03
4039 Design, Construction, and Functional Characterization of a tRNA Neochromosome in Yeast
Schindler, D.; Walker, R. S. K.; Jiang, S.; Brooks, A. N.; Wang, Y.; Mueller, C. A.; Cockram, C.; Luo, Y.; Garcia, A.; Schraivogel, D.; Mozziconacci, J.; Blount, B. A.; Cai, J.; Ogunlana, L.; Liu, W.; Joensson, K.; Abramczyk, D.; Garcia-Ruiz, E.; Turowski, T. W.; Swidah, R.; Ellis, T.; Antequera, F.; Shen, Y.; Nieduszynski, C. A.; Koszul, R.; Dai, J.; Steinmetz, L. M.; Boeke, J. D.; Cai, Y.
10.1101/2022.10.03.510608 — synthetic biology — Posted on 2022-10-03
4043 A seven transmembrane-integral methyltransferase catalysing N-terminal histidine methylation of lytic polysaccharide monooxygenases
Batth, T. S.; Simonsen, J. L.; Rollan, C. H.; Brander, S.; Morth, J. P.; Johansen, K. S.; Norholm, M. H. H.; Hoof, J. B.; Olsen, J. V.
10.1101/2022.10.03.510680 — molecular biology — Posted on 2022-10-03
4045 Intranasal delivery of NS1-deleted influenza virus vectored COVID-19 vaccine restrains the SARS-CoV-2 inflammatory response
Zhang, L.; Jiang, Y.; He, J.; Chen, J.; Qi, R.; Yuan, L.; Shao, T.; Chen, C.; Chen, Y.; Wang, X.; Lei, X.; Gao, Q.; Zhuang, C.; Zhou, M.; Ma, J.; Liu, W.; Yang, M.; Fu, R.; Wu, Y.; Chen, F.; Xiong, H.; Nie, M.; Chen, Y.; Wu, K.; Fang, M.; Wang, Y.; Zheng, Z.; Huang, S.; Ge, S.; Cheng, S.-C.; Zhu, H.; Chen, T.; Yuan, Q.; Wu, T.; Zhang, J.; Chen, Y.; Zhang, T.; Qi, H.; Guan, Y.; Xia, N.
10.1101/2022.10.03.510566 — immunology — Posted on 2022-10-03
4046 Dorsal root ganglia control nociceptive input to the central nervous system
Han, H.; Ramli, R.; Wang, C.; Liu, C.; Shah, S.; Mullen, P.; Lall, V.; Jones, F.; Shao, J.; Zhang, H.; Jaffe, D. B.; Gamper, N.; Du, X.
10.1101/2021.07.14.452325 — neuroscience — Posted on 2022-10-03
4050 Curation of the Deep Green list of unannotated green lineage proteins to enable structural and functional characterization
Knoshaug, E.; Sun, P.; Nag, A.; Nguyen, H.; Mattoon, E.; Zhang, N.; Liu, J.; Chen, C.; Cheng, J.; Zhang, R.; St. John, P. C.; Umen, J. G.
10.1101/2022.09.30.510186 — plant biology — Posted on 2022-10-03
4051 Chromatin regulators in the TBX1 network confer risk for conotruncal heart defects in 22q11.2DS and sporadic congenital heart disease
Zhao, Y.; Wang, Y.; Shi, L.; McDonald-McGinn, D. M.; Crowley, T. B.; McGinn, D. E.; Tran, O. T.; Miller, D.; Zackai, E.; Johnston, H. R.; Chow, E.; Vorstman, J. A. S.; Vingerhoets, C.; van Amelsvoort, T.; Gothelf, D.; Swillen, A.; Breckpot, J.; Vermeesch, J. R.; Eliez, S.; Schneider, M.; van den Bree, M. B.; Owen, M. J.; Kates, W.; Repetto, G. M.; Shashi, V.; Schoch, K.; Bearden, C. E.; Digilio, M. C. E.; Unolt, M.; Putotto, C.; Marino, B.; Pontillo, M.; Armando, M.; Vicari, S.; Angkustsiri, K.; Campbell, L.; Busa, T.; Heine-Suner, D.; Murphy, K. C.; Murphy, D.; Garcia-Minaur, S.; Fernandez, L
10.1101/2022.09.30.507111 — genetics — Posted on 2022-10-03
4054 Defective neuritogenesis in Abcd1/2 deficient rat neurons due to intrinsic and astrocyte-dependent mechanisms
Golbano, A.; Pardo, L.; Menacho, C. M.; Rierola, M.; Claro, E.; Wood, L. B.; Masgrau, R.; Galea, E.
10.1101/2022.09.30.510337 — neuroscience — Posted on 2022-10-03
4055 Resting-State Electroencephalography for Continuous, Passive Prediction of Coma Recovery After Acute Brain Injury
Zabihi, M.; Rubin, D. B.; Ack, S. E.; Gilmore, E. J.; Junior, V. M.; Zafar, S. F.; Li, Q.; Young, M. J.; Edlow, B. L.; Bodien, Y. G.; Rosenthal, E. S.
10.1101/2022.09.30.510334 — neuroscience — Posted on 2022-10-03
4059 Acoustic and Neurophysiological Aspects of Lombard Effect
Castro, C.; Z Rivera, L.; Prado, P.; Cuadros, J.; Cortes, J. P.; Espinoza, V.; Weinstein, A.; Zanartu, M.
10.1101/2022.09.30.510383 — neuroscience — Posted on 2022-10-03
4060 A ubiquitous spectrolaminar motif of local field potential power across the primate cortex
Mendoza-Halliday, D.; Major, A. J.; Lee, N.; Lichtenfeld, M.; Carlson, B.; Mitchell, B.; Meng, P. D.; Xiong, Y.; Westerberg, J. A.; Maier, A.; Desimone, R.; Miller, E. K.; Bastos, A. M.
10.1101/2022.09.30.510398 — neuroscience — Posted on 2022-10-03
4062 Reproducibility of spatial summation of pain effect during COVID-19 pandemic
Nastaj, J.; Skalski, J.; Budzisz, A.; Szikszay, T. M.; Swoboda, S.; Kowalska, W.; Nowak, D.; Zbroja, E.; Kruszyna, N.; Jakubinska, M.; Grygny, D.; Polczyk, R.; Malecki, A.; Luedtke, K.; Adamczyk, W. M.
10.1101/2022.09.30.510274 — physiology — Posted on 2022-10-03
4068 READemption 2: Multi-species RNA-Seq made easy
Sauerwein, T. D.; Bischler, T. D.; Foerstner, K. U.
10.1101/2022.09.30.510338 — bioinformatics — Posted on 2022-10-03
4070 Pneumatic Controlled Nano-Sieve for Efficient Capture and Release of Nanoparticles
Nanaware, A.; Kranbuhl, T.; Ching, J.; Chen, J. S.; Chen, X.; Tu, H.; Du, K.
10.1101/2022.09.30.510404 — bioengineering — Posted on 2022-10-03
4077 Predator-mediated interactions through changes in predator home range size can lead to prey local exclusion
Beardsell, A.; Berteaux, D.; Dulude-de-Broin, F.; Gauthier, G.; Clermont, J.; Gravel, D.; Bety, J.
10.1101/2022.09.30.510100 — ecology — Posted on 2022-10-03
4082 Intermediately Synchronised Brain States optimise trade-off between Subject Identifiability and Predictive Capacity
Sasse, L.; Larabi, D. I.; Omidvarnia, A.; Jung, K.; Hoffstaedter, F.; Jocham, G.; Eickhoff, S. B.; Patil, K. R.
10.1101/2022.09.30.510304 — neuroscience — Posted on 2022-10-03
4083 A primary rodent triculture model to investigate the role of glia-neuron crosstalk in regulation of neuronal activity.
Phadke, L.; Lau, D. H. W.; Aghaizu, N. D.; Ibarra, S.; Navarron, C. M.; Granat, L.; Magno, L.; Whiting, P.; Jolly, S.
10.1101/2022.09.30.510271 — neuroscience — Posted on 2022-10-03
4084 Hippocampal firing fields anchored to a moving object predict homing direction during path-integration-based behavior
Najafian Jazi, M.; Tymorek, A.; Yen, T. Y.; Kavarayil, F. J.; Stingl, M.; Chau, S. R.; Baskurt, B.; Garcia Vilela, C.; Allen, K.
10.1101/2022.09.30.510268 — neuroscience — Posted on 2022-10-03
4085 "Wissenschaft fürs Wohnzimmer" - two years of interactive, scientific livestreams weekly on YouTube
Stoll, N.; Wietz, M.; Juricke, S.; Pausch, F.; Peter, C.; Massing, J. C.; Seifert, M.; Zeising, M.; Kaess, M.; McPherson, R.; Suckow, B.
10.1101/2022.09.30.509854 — scientific communication and education — Posted on 2022-10-03
4086 On the synergies between ribosomal assembly and machine learning tools for microbial identification
Chau, S.; Rojas, C.; Jetcheva, J.; Vijayakumar, S.; Yuan, S.; Stowbunenko, V.; Shelton, A. N.; Andreopoulos, W. B.
10.1101/2022.09.30.510284 — bioinformatics — Posted on 2022-10-03
4087 Protein Language Model Predicts Mutation Pathogenicity and Clinical Prognosis
Liu, X.; Yang, X.; Ouyang, L.; Guo, G.; Su, J.; Xi, R.; Yuan, K.; Yuan, F.
10.1101/2022.09.30.510294 — bioinformatics — Posted on 2022-10-03
4088 Topic modeling for multi-omic integration in the human gut microbiome and implications for autism
Tataru, C.; Peras, M.; Rutherford, E.; Dunlap, K.; Yin, X.; Chrisman, B. S.; DeSantis, T. Z.; Wall, D. P.; Iwai, S.; David, M. M.
10.1101/2022.09.30.509056 — bioinformatics — Posted on 2022-10-03
4092 Interactions between supervised and reinforcement learning processes in a neurorobotic model
Capirchio, A.; Ponte, C.; Baldassarre, G.; Mannella, F.; Pelosin, E.; Caligiore, D.
10.1101/2022.09.30.510289 — bioengineering — Posted on 2022-10-03
4093 We the Hunted
Martin, J.; Leece, A.; Herries, A. I.; Baker, S.; Strait, D.
10.1101/2022.09.29.510060 — evolutionary biology — Posted on 2022-10-03
4094 Rapid reduction of Paraoxonase expression followed by inactivation across semiaquatic mammals suggests adaptive benefit of gene loss
Graham, A. M.; Jamison, J. M.; Bustos, M.; Furlong, C. E.; Richter, R.; Marsillach, J.; Presnell, J. S.; Crocker, D. E.; Rea, L. D.; Michaels, A.; Fustukjian, A.; Meyer, W. K.; Clark, N. L.
10.1101/2022.09.29.510191 — evolutionary biology — Posted on 2022-10-03
4095 Host-plant adaptation as a driver of incipient speciation in the fall armyworm (Spodoptera frugiperda)
Fiteni, E.; Durand, K.; Gimenez, S.; Meagher, R. L.; Legeai, F.; Kergoat, G. J.; Negre, N.; d'Alencon, E.; NAM, K.
10.1101/2022.09.30.510290 — evolutionary biology — Posted on 2022-10-03
4096 Phylogeographic breaks and how to find them: Separating vicariance from isolation by distance in a lizard with restricted dispersal
Rancilhac, L.; Miralles, A.; Geniez, P.; Mendez-Aranda, D.; Beddek, M.; Brito, J. C.; Leblois, R.; Crochet, P.-A.
10.1101/2022.09.30.510256 — evolutionary biology — Posted on 2022-10-03
4098 CiDRE+ M2c macrophages hijacked by SARS-CoV-2 cause COVID-19 severity
Mitsui, Y.; Suzuki, T.; Kuniyoshi, K.; Inamo, J.; Yamaguchi, K.; Komuro, M.; Watanabe, J.; Edamoto, M.; Li, S.; Kouno, T.; Oba, S.; Hosoya, T.; Koyama, S.; Sakaguchi, N.; Standley, D. M.; Shin, J. W.; Akira, S.; Yasuda, S.; Miyazaki, Y.; Kochi, Y.; Kumanogoh, A.; Okamoto, T.; Satoh, T.
10.1101/2022.09.30.510331 — immunology — Posted on 2022-10-03
4099 Maternal dietary deficiencies in folates or choline during pregnancy and lactation worsen stroke outcome in 3-month-old male and female mouse offspring
Clementson, M.; Hurley, L.; Coonrod, S.; Bennett, C.; Marella, P.; Pascual, A.; Pull, K.; Bottiglieri, T.; Patterson, B.; Malysheva, O.; Caudill, M.; Jadavji, N. M.
10.1101/2022.09.28.509960 — neuroscience — Posted on 2022-10-03
4100 Novel inductively-coupled ear-bars (ICEs) for fMRI signal enhancement in rat entorhinal cortex
Chen, Y.; Fernandez, Z.; Zhu, D. C.; Counts, S. E.; Dorrance, A. M.; Yu, X.; Scheel, N.; Qian, W.; Gifani, M.; Qian, C.
10.1101/2022.09.30.510293 — neuroscience — Posted on 2022-10-03
4103 Adsorption Race Between Activated Carbon and Lactase for Intermolecular Interaction with Lactose
Zumrutdal, E.; Kusvuran, E.; Kokbas, U.; Mertoglu, T. S.; Curuk, M.; Dag, B.; Kilincceker, G.
10.1101/2022.09.29.510224 — bioengineering — Posted on 2022-10-03
4107 Crystal structure of monkeypox H1 phosphatase, an Antiviral Drug Target
Cui, W.; Huang, H.; Duan, Y.; Luo, Z.; Wang, H.; Zhang, T.; Nguyen, H.; Shen, W.; Su, D.; Ji, X.; Yang, H.; Wang, W.
10.1101/2022.09.30.510410 — microbiology — Posted on 2022-10-03
4109 Photoacoustic imaging reveals transient decrease of oxygenation in murine blood due to monoclonal IgG4 antibody
Khadria, A.; Paavola, C. D.; Maslov, K.; Brown-Augsburger, P. L.; Grealish, P. F.; Lozano, E.; Blankenship, R. L.; Cao, R.; Shi, J.; Beals, J. M.; Oladipupo, S. S.; Wang, L. V.
10.1101/2022.09.29.509334 — immunology — Posted on 2022-10-03
4110 Altered CD8+ T cell associated aging gene signature in the peripheral blood of patients with Alzheimer's disease.
Young, J. J.; Park, H.-J.; Kim, M.; Par-Young, J.; Bartlett, H. H.; Kim, H. S.; Shin, M. S.; Unlu, S.; Bucala, R. J.; Van Dyck, C. H.; Allore, H. G.; Mecca, A. P.; You, S.; Kang, I.
10.1101/2022.09.29.510171 — immunology — Posted on 2022-10-03
4111 Noradrenergic input from nucleus of the solitary tract regulates parabrachial activity in mice
Onwukwe, C.; Ji, Y.; Smith, J.; Laub, H.; Posa, L.; Keller, A.; Masri, R.; Cramer, N.
10.1101/2022.09.29.510103 — neuroscience — Posted on 2022-10-03
4113 Imaging crossing fibers in mouse, pig, monkey, and human brain using small-angle X-ray scattering
Georgiadis, M.; Menzel, M.; Reuter, J. A.; Born, D.; Kovacevich, S.; Alvarez, D.; Gao, Z.; Guizar-Sicairos, M.; Weiss, T. M.; Axer, M.; Rajkovic, I.; Zeineh, M. M.
10.1101/2022.09.30.510198 — neuroscience — Posted on 2022-10-03
4115 Biophysical characterisation of the structure of a SARS-CoV-2 self-amplifying - RNA (saRNA) vaccine
Myatt, D. P.; Wharram, L.; Graham, C.; Liddell, J.; Branton, H.; Pizzey, C.; Cowieson, N.; Rambo, R.; Shattock, R.
10.1101/2022.10.03.507132 — biophysics — Posted on 2022-10-03
4117 Memory in Repetitive Protein-Protein Interaction Series -- in Memory of the Late Professor Robert M. Nerem
Rosado, A. M.; Zhang, Y.; Choi, H.-K.; Elrich, S. M.; Jin, F.; Grakoui, A.; Evavold, B. D.; Zhu, C.
10.1101/2022.10.01.510459 — biophysics — Posted on 2022-10-03
4119 Elucidation of small molecule passive permeation across lipid membranes using conventional solution state NMR methods
Serrano-Sanchez, A.; Cassar, J.; White, L. J.; Popoola, P. I. A.; Hiscock, J. R.; Ortega-Roldan, J. L.
10.1101/2022.10.01.510446 — biophysics — Posted on 2022-10-03
4120 Spatial proteomics and iPSC modeling uncover mechanisms of axonal pathology in Alzheimer's disease
Cai, Y.; Kanyo, J.; Wilson, R.; Mansuri, M. S.; Cardozo, P. L.; Goshay, D.; Tian, Z.; Braker, A.; Trinh, H. K.; Lam, T.; Brennand, K.; Nairn, A. C.; Grutzendler, J.
10.1101/2022.09.30.510408 — neuroscience — Posted on 2022-10-03
4122 Optical Metabolic Imaging Uncovers Sex- and Diet-dependent Lipid Changes in Aging Drosophila Brain
Li, Y.; Chang, P.; Sankaran, S.; Jang, H.; Nie, Y.; Zeng, A.; Hussain, S.; Wu, J. Y.; Chen, X.; Shi, L.
10.1101/2022.10.01.510416 — bioengineering — Posted on 2022-10-03
4123 The black goby Gobius niger Linnaeus, 1758 in the Marchica lagoon (Alboran Sea, Morocco): Ecological traits and site-related footprint
Lamkhalkhal, A.; Selfati, M.; Rahmouni, I.; Kaddouri, N.; Badaoui, B.; pariselle, A.; Benhoussa, A.; Kmentova, N.; Vanhove, M. P. M.; Bazairi, H.
10.1101/2022.10.02.510494 — ecology — Posted on 2022-10-03
4124 Learning representations for image-based profiling of perturbations
Moshkov, N.; Bornholdt, M.; Benoit, S.; McQuin, C.; Smith, M.; Goodman, A.; Senft, R.; Han, Y.; Babadi, M.; Horvath, P.; Cimini, B. A.; Carpenter, A. E.; Singh, S.; Caicedo, J. C.
10.1101/2022.08.12.503783 — bioinformatics — Posted on 2022-10-03
4126 Yeast NDI1 reconfigures neuronal metabolism and prevents the unfolded protein response in mitochondrial complex I deficiency
Granat, L.; Ranson, D.; Hamer, E.; Chakrabarty, R. P.; Mattedi, F.; Fort-Aznar, L.; Hirth, F.; Sweeney, S.; Vagnoni, A.; Chandel, N. S.; Bateman, J. M.
10.1101/2022.09.22.509020 — neuroscience — Posted on 2022-10-03
4128 Chikungunya virus transmission in the Southernmost state of Brazil was characterized by self-limited cases (2017 to 2019) and a larger 2021 outbreak
Gregianini, T. S.; Salvato, R. S.; Barcellos, R. B.; Godinho, F. M.; Ruivo, A. P.; de Melo, V. H.; Schroder, J. A.; Martiny, F. L.; Mollmann, E. B.; Favreto, C.; Baethgen, L. F.; Ferreira, V. P.; de Lima, L. E.; Piazza, C. F.; Machado, T. R. M.; Becker, I. M.; Ramos, R. R.; Frolich, G. C.; Rossetti, A. F.; Almeida, L. d. C.; Rodrigues, T. M. A.; Braganca, I. T.; Campos, A. A. S.; Manzoni, V. B.; Machado, L. C.; da Silva, L. M. I.; de Oliveira, A. L. A.; Paiva, M. H. S.; Nunes, Z. M. A.; de Almeida, P. R.; Demoliner, M.; Gularte, J. S.; da Silva, M. S.; Filippi, M.; Pereira, V. M. d. A. G.; Spi
10.1101/2022.09.30.510389 — molecular biology — Posted on 2022-10-03
4130 Memory CD4 T cell subset organization in the female reproductive tract is regulated via the menstrual cycle through CCR5 signaling
Swaims-Kohlmeier, A.; Wein, A. N.; Hardnett, F. P.; Sheth, A. N.; Li, Z.-R. T.; Williams, M. E.; Radzio-Basu, J.; Zheng, H.; Dinh, C.; Haddad, L. B.; Collins, E. M.; Lobby, J. L.; Kost, K.; Hayward, S. L.; Ofotokun, I.; Antia, R.; Scharer, C. D.; Lowen, A. C.; Garcia-Lerma, J. G.; Kohlmeier, J.
10.1101/2022.10.01.510445 — immunology — Posted on 2022-10-03
4131 Overexpression of AMPKγ2 increases AMPK signaling to augment human T cell metabolism and function
Braverman, E.; McQuaid, M.; Monlish, D.; Dobbs, A.; Ramsey, M.; Ramgopal, A.; Brown, H.; Byersdorfer, C.
10.1101/2022.10.01.510473 — immunology — Posted on 2022-10-03
4132 A single-cell multi-omic atlas spanning the adult rhesus macaque brain
Chiou, K. L.; Huang, X.; Bohlen, M. O.; Tremblay, S.; O'Day, D. R.; Spurrell, C. H.; Gogate, A. A.; Zintel, T. M.; Cayo Biobank Research Unit, ; Andrews, M. G.; Martinez, M. I.; Starita, L. M.; Montague, M. J.; Platt, M. L.; Shendure, J.; Snyder-Mackler, N.
10.1101/2022.09.30.510346 — neuroscience — Posted on 2022-10-03
4133 KapBeta2 is a modifier of the C9orf72-linked glycine-arginine dipeptide neurotoxicity
cicardi, M. e.; Kankate, V.; Sriramoji, S.; Krishnamurthy, K.; ShamamandriMarkandaiah, S.; Verdone-Morris, B.; Girdhar, A.; Nelson, A. T.; Rivas, L. B.; Boehringer, A.; Haeusler, A.; Pasinelli, P.; Guo, L.; Trotti, D.
10.1101/2022.09.30.510384 — neuroscience — Posted on 2022-10-03
4134 Task-based attentional and default mode connectivity associated with STEM anxiety profiles among university physics students
Smith, D. D.; Meca, A.; Bottenhorn, K. L.; Bartley, J. E.; Riedel, M. C.; Salo, T.; Peraza, J. A.; Laird, R. W.; Pruden, S. M.; Sutherland, M. T.; Brewe, E.; Laird, A. R.
10.1101/2022.09.30.508557 — neuroscience — Posted on 2022-10-03
4135 Therapeutic depletion of CD8+ T-cells prevents myelin pathology in Globoid Cell Leukodystrophy
Sutter, P. A.; Menoret, A.; Jellison, E. R.; Nicaise, A. M.; Bradbury, A. M.; Vella, A. T.; Bongarzone, E. R.; Crocker, S. J.
10.1101/2022.09.30.510367 — neuroscience — Posted on 2022-10-03
4137 JGI Plant Gene Atlas: An updateable transcriptome resource to improve structural annotations and functional gene descriptions across the plant kingdom
Sreedasyam, A.; Plott, C.; Hossain, M. S.; Lovell, J. T.; Grimwood, J.; Jenkins, J. W.; Daum, C.; Barry, K.; Carlson, J.; Shu, S.; Phillips, J.; Amirebrahimi, M.; Zane, M.; Wang, M.; Goodstein, D.; Haas, F. B.; Hiss, M.; Perroud, P. F.; Jawdy, S. S.; Hu, R.; Johnson, J.; Kropat, J.; Gallaher, S. D.; Lipzen, A.; Tillman, R.; Shakirov, E. V.; Weng, X.; Torres-Jerez, I.; Weers, B.; Conde, D.; Pappas, M. R.; Liu, L.; Muchlinski, A.; Jiang, H.; Shyu, C.; Huang, P.; Sebastian, J.; Laiben, C.; Medlin, A.; Carey, S.; Carrell, A. A.; Perales, M.; Swaminathan, K.; Allona, I.; Grattapaglia, D.; Cooper, E
10.1101/2022.09.30.510380 — plant biology — Posted on 2022-10-03
4140 Pro-tumor and prothrombotic activities of hepsin in colorectal cancer cells and suppression by venetoclax
Rodenas, M. C.; Penas-Martinez, J.; Pardo-Sanchez, I.; Zaragoza Huesca, D.; Ortega-Sabater, C.; Pena-Garcia, J.; Espin, S.; Ricote, G.; Montenegro, S.; Ayala de la Pena, F.; Luengo-Gil, G.; Nieto, A.; Garcia-Molina, F.; Vicente, V.; Bernardi, F.; Lozano, M. L.; Mulero, V.; Perez-Sanchez, H.; Carmona-Bayonas, A.; Martinez-Martinez, I.
10.1101/2022.10.01.510038 — cancer biology — Posted on 2022-10-03
4141 Targeting plasma membrane and mitochondrial instability in breast cancer cells and breast epithelial to mesenchymal transition-model cells by adamantyl diaza-crown ether ZG613
Ester, K.; Mioc, M.; Spurny, P.; Bonhenry, D.; Marjanovic, M.; Uzelac, L.; Gabrilo, J.; Sumanovac, T.; Schreibmayer, W.; Majerski, K.; Minofar, B.; Ludwig, J.; Kralj, M.
10.1101/2022.09.30.510273 — cancer biology — Posted on 2022-10-03
4144 Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins
Kubo, S.; Black, C. S.; Joachimiak, E.; Yang, S. K.; Legal, T.; Peri, K.; Khalifa, A.; Miandoab, A. G.; Valente, M.; de Bellis, C.; Huynh, P.; Fan, Z.; Wloga, D.; Bui, K. H.
10.1101/2022.09.30.510376 — biophysics — Posted on 2022-10-03
4145 Integrative Cut&Tag/RNA-Seq analysis of histone variant macroH2A1-dependent orchestration of human iPSCs reprogramming
Liorni, N.; Napoli, A.; Castellana, S.; Giallongo, S.; Rehakova, D.; Lo Re, O.; Koutna, I.; Mazza, T.; Vinciguerra, M.
10.1101/2022.09.30.510248 — bioinformatics — Posted on 2022-10-03
4146 Microphysiological Drug-Testing Platform For Identifying Responses To Prodrug Treatment In Primary Leukemia
Gokce, F.; Kaestli, A.; Lohasz, C.; de Geus, M.; Kaltenbach, H. M.; Renggli, K.; Bornhauser, B.; Hierlemann, A.; Modena, M. M.
10.1101/2022.04.06.483760 — bioengineering — Posted on 2022-10-03
4150 Design principles for selective polarization of PAR proteins by cortical flows
Illukkumbura, R.; Hirani, N.; Borrego-Pinto, J.; Bland, T.; Ng, K.; Hubatsch, L.; McQuade, J.; Endres, R.; Goehring, N.
10.1101/2022.09.05.506621 — cell biology — Posted on 2022-10-03
4152 Stacked binding of a small molecule PET tracer to Alzheimer's tau paired helical filaments
Merz, G. E.; Chalkley, M. J.; Tan, S. K.; Tse, E.; Lee, J.; Prusiner, S. B.; Paras, N. A.; DeGrado, W. F.; Southworth, D. R.
10.1101/2022.09.30.510175 — biophysics — Posted on 2022-10-03
4154 Comprehensive volumetric phenotyping of the neonatal brain in Down syndrome.
Fukami - Gartner, A.; Baburamani, A.; Dimitrova, R.; Patkee, P. A.; Ojinaga Alfageme, O.; Bonthrone, A. F.; Cromb, D.; Uus, A.; Counsell, S. J.; Hajnal, J. V.; O'Muircheartaigh, J.; Rutherford, M. A.
10.1101/2022.09.30.510205 — neuroscience — Posted on 2022-10-03
4155 High sensitivity limited material proteomics empowered by data-independent acquisition on linear ion traps
Phlairaharn, T.; Gregoire, S.; Woltereck, L. R.; Petrosius, V.; Furtwaengler, B.; Searle, B. C.; Schoof, E. M.
10.1101/2022.06.27.497681 — systems biology — Posted on 2022-10-02
4157 QuNex -- An Integrative Platform forReproducible Neuroimaging Analytics
Ji, J. L.; Demsar, J.; Fonteneau, C.; Tamayo, Z.; Pan, L.; Kraljic, A.; Matkovic, A.; Purg, N.; Helmer, M.; Warrington, S.; Winkler, A.; Zerbi, V.; Coalson, T. S.; Glasser, M. F.; Harms, M. P.; Sotiropoulos, S.; Murray, J. D.; Anticevic, A.; Repovs, G.
10.1101/2022.06.03.494750 — neuroscience — Posted on 2022-10-02
4160 Cardiac MAO-A inhibition protects against catecholamine-induced ventricular arrhythmias via enhanced diastolic calcium control
Shi, Q.; Malik, H.; Streeter, J.; Wang, J.; Huo, R.; Crawford, R. M.; Shih, J. C.; Chen, B.; Hall, D.; Abel, E. D.; Song, L.-S.; Anderson, E. J.
10.1101/2022.09.29.510139 — physiology — Posted on 2022-10-02
4161 Contrast-free Super-resolution Doppler (CS Doppler) based on Deep Generative Neural Networks
You, Q.; Lowerison, M.; Shin, Y.; Chen, X.; Chandra Sekaran, N. V.; Dong, Z.; Llano, D. A.; Anastasio, M. A.; Song, P.
10.1101/2022.09.29.510188 — bioengineering — Posted on 2022-10-02
4165 Iterative immunostaining combined with expansion microscopy and image processing reveals nanoscopic network organization of nuclear lamina
Mantyla, E.; Montonen, T.; Azzari, L.; Mattola, S.; Hannula, M.; Vihinen-Ranta, M.; Hyttinen, J.; Vippola, M.; Foi, A.; Nymark, S.; Ihalainen, T. O.
10.1101/2022.09.27.509734 — molecular biology — Posted on 2022-10-02
4166 DELE1 oligomerization promotes integrated stress response activation
Yang, J.; Baron, K. R.; Pride, D. E.; Schneemann, A.; Guo, X.; Chen, W.; Song, A. S.; Aviles, G.; Kampmann, M.; Wiseman, R. L.; Lander, G. C.
10.1101/2022.10.01.510468 — molecular biology — Posted on 2022-10-02
4168 Signatures of Microbial Diversity at Multiple Scales of Resolution within Engineered Enrichment Communities
McDaniel, E. A.; Moya-Flores, F.; Mendez, D.; Wethersby, C.; Oyserman, B. O.; Flowers, J.; He, S.; Petriglieri, F.; Singleton, C.; Nielsen, P. H.; McMahon, K.
10.1101/2022.10.01.510452 — microbiology — Posted on 2022-10-02
4169 Contribution of 6mer seed toxicity to HIV-1 induced cytopathicity
Vaidyanathan, A.; Taylor, H. E.; Hope, T. J.; D'Aquila, R. T.; Bartom, E. T.; Hultquist, J. F.; Peter, M. E.
10.1101/2022.10.01.510471 — microbiology — Posted on 2022-10-02
4171 Mesoscale cortex-wide neural dynamics predict goal-directed, but not random actions in mice several seconds prior to movement
Mitelut, C.; Zhang, Y.; Sekino, Y.; Boyd, J.; Bolanos, F.; Swindale, N. V.; Silasi, G.; Saxena, S.; Murphy, T. H.
10.1101/2021.12.17.473193 — neuroscience — Posted on 2022-10-02
4172 NPEPPS regulates intracellular import and sensitivity to cisplatin by interaction with volume regulated anion channels
Jones, R. T.; Goodspeed, A.; Mohapatra, S.; Feldman, L. E.; Scholtes, M.; Vekony, H.; Jean, A.; Tilton, C. B.; Orman, M. V.; Deiter, C.; Xander, N.; Araki, S.; Joshi, M.; Javaid, M.; Clambey, E. T.; Layer, R.; Laajala, T. D.; Parker, S.; Zuiverloon, T.; Theodorescu, D.; Costello, J. C.
10.1101/2021.03.04.433676 — cancer biology — Posted on 2022-10-02
4173 On the reproductive mechanism of Gram-negative protocells
Kanaparthi, D.; Lampe, M.; Krohn, J. H.; Zhu, B.; Klingl, A.; Lueders, T.
10.1101/2021.11.25.470037 — biophysics — Posted on 2022-10-02
4174 On the reproductive mechanisms of protocells
Kanaparthi, D.; Lampe, M.; Krohn, J. H.; Hildebrand, F.; Boesen, T.; Klingl, A.; Phapale, P.; Lueders, T.
10.1101/2021.11.25.470039 — biophysics — Posted on 2022-10-02
4176 Engineering a plant polyketide synthase for the biosynthesis of methylated flavonoids
Peng, B.; Zhang, L.; He, S.; Oerlemans, R.; Quax, W. J.; Groves, M. R.; Haslinger, K.
10.1101/2022.10.02.510496 — biochemistry — Posted on 2022-10-02
4177 DNA Modifications Enabling Proximity Biotinylation
Wilbanks, B.; Pearson, K.; Byrne, S.; Bickart, L.; Dedon, P.; Maher, L. J.
10.1101/2022.10.02.510503 — biochemistry — Posted on 2022-10-02
4182 Fusome topology and inheritance during insect gametogenesis
Diegmiller, R.; Imran Alsous, J.; Li, D.; Yamashita, Y. M.; Shvartsman, S.
10.1101/2022.05.18.492500 — developmental biology — Posted on 2022-10-02
4185 Internal needs drive the cephalic phase response in Drosophila melanogaster
Umezaki, Y.; Hidalgo, S.; Nguyen, E.; Nguyen, T.; Suh, J.; Uchino, S. S.; Chiu, J. C.; Hamada, F. N.
10.1101/2022.09.30.510382 — neuroscience — Posted on 2022-10-02
4186 Cellular proteomic profiling using proximity labelling by TurboID-NES in microglial and neuronal cell lines.
Sunna, S.; Bowen, C.; Zeng, H.; Rayaprolu, S.; Kumar, P.; Bagchi, P.; Guo, Q.; Duong, D. M.; Bitarafan, S.; Natu, A.; Wood, L.; Seyfried, N. T.; Rangaraju, S.
10.1101/2022.09.27.509765 — neuroscience — Posted on 2022-10-02
4187 Integrative single cell and spatial transcriptomics of colorectal cancer reveals multicellular functional units that support tumor progression
Avraham-Davidi, I.; Mages, S.; Klughammer, J.; Moriel, N.; Imada, S.; Hofree, M.; Murray, E.; Chen, J.; Pelka, K.; Mehta, A.; Boland, G. M.; Delorey, T. M.; Caplan, L.; Dionne, D.; Tirosh, I.; Hacohen, N.; Chen, F.; Yilmaz, O. H.; Roper, J.; Rozenblatt-Rosen, O.; Nitzan, M.; Regev, A.
10.1101/2022.10.02.508492 — cancer biology — Posted on 2022-10-02
4189 An FGF Timer for Zygotic Genome Activation
Treen, N.; Chavarria, E.; Weaver, C. J.; Brangwynne, C. P.; Levine, M.
10.1101/2022.10.01.510450 — developmental biology — Posted on 2022-10-02
4191 The Formation of Biogenic Guanine Crystals Closely Resembles Melanosome Morphogenesis
Wagner, A.; Upcher, A.; Maria, R.; Magnesen, T.; Zelinger, E.; Raposa, G.; Palmer, B. A.
10.1101/2022.10.01.510454 — cell biology — Posted on 2022-10-02
4194 Transient, developmental exposure to patient-derived anti-NMDA receptor autoantibodies causes long-term axonal and behavioral defects
Zhou, J.; Greenfield, A.; Loudermilk, R.; Bartley, C.; Tran, B.; Zhao, C.; Wang, H.; Wilson, M.; Pleasure, S.
10.1101/2022.09.29.510196 — neuroscience — Posted on 2022-10-02
4198 Enteroendocrine cells protect the stem cell niche by regulating crypt metabolism in response to nutrients
McCauley, H. A.; Riedman, A. M.; Enriquez, J. R.; Zhang, X.; Watanabe-Chailland, M.; Sanchez, J. G.; Kechele, D. O.; Paul, E. F.; Riley, K.; Burger, C.; Lang, R. A.; Wells, J. M.
10.1101/2022.10.01.508931 — cell biology — Posted on 2022-10-02
4200 HY5 Regulates GLK and GNC Transcription Factors to Orchestrate Photomorphogenesis in Arabidopsis thaliana
Zhang, T.; Zhang, R.; Zeng, X.; Ye, L.; Tian, S.; Zhang, Y.; Zhou, W. B.; Zhu, X.-G.; Wang, P.
10.1101/2022.09.30.510343 — plant biology — Posted on 2022-10-02
4201 Regulation by cyclic-di-GMP attenuates dynamics and enhances robustness of bimodal curli gene activation in Escherichia coli
Lamprecht, O.; Ratnikava, M.; Jacek, P.; Kaganovitch, E.; Buettner, N.; Fritz, K.; Biazruchka, I.; Köhler, R.; Pietsch, J.; Sourjik, V.
10.1101/2022.05.23.493020 — microbiology — Posted on 2022-10-02
4203 Flavonols contrary affect the interconnected glucosinolate and camalexin biosynthesis pathway in Arabidopsis thaliana
Naik, J.; Tyagi, S.; Rajput, R.; Kumar, P.; Pucker, B.; Bisht, N. C.; Misra, P.; Stracke, R.; Pandey, A.
10.1101/2022.10.01.510434 — plant biology — Posted on 2022-10-02
4204 Mesenchymal-epithelial transition in lymph node metastases of oral squamous cell carcinoma is accompanied by ZEB1 expression
Horny, K.; Sproll, C.; Peiffer, L.; Furtmann, F.; Gerhardt, P.; Gravemeyer, J.; Stoecklein, N. H.; Spassova, I.; Becker, J. C.
10.1101/2022.02.03.478962 — cancer biology — Posted on 2022-10-02
4209 Notch signaling pathway in tooth shape variations
Mitsiadis, T.; Pagella, P.; Gomez Rodrigues, H.; Tsouknidas, A.; Ramenzoni, L. L.; Radtke, F.; Mehl, A.; Viriot, L.
10.1101/2022.09.30.510272 — developmental biology — Posted on 2022-10-02
4210 Recycling limits the lifetime of actin turnover
Blanchoin, L.; Thery, M.; Colin, A.; Kotila, T.; Guerin, C.; Orhant-Prioux, M.; Vianay, B.; Mogilner, A.; Lappalainen, P.
10.1101/2022.09.30.510257 — cell biology — Posted on 2022-10-02
4214 Malt1-dependent cleavage of Tensin-3 controls B-cell adhesion and lymphomagenesis
Juilland, M.; Alouche, N.; Ubezzi, I.; Gonzalez, M.; Erdmann, T.; Lenz, G.; Luther, S. A.; Thome, M.
10.1101/2022.09.29.510036 — immunology — Posted on 2022-10-02
4216 Lipid droplets are intracellular mechanical stressors that promote hepatocyte dedifferentiation
Loneker, A. E.; Alisafaei, F.; Kant, A.; Janmey, P. A.; Shenoy, V. B.; Wells, R. G.
10.1101/2022.08.27.505524 — cell biology — Posted on 2022-10-02
4219 Inhibition of Casein Kinase 2 induces cell death in chronic myelogenous leukemia cells resistant to tyrosine kinase inhibitors
Mitrovsky, O.; Myslivcova, D.; Machackova-Lopotova, T.; Obr, A.; Cermakova, K.; Ransdorfova, S.; Brezinova, J.; Klamova, H.; Zackova, M.
10.1101/2021.06.28.450156 — cancer biology — Posted on 2022-10-02
4220 A Rigid Parallel-Plate Oxygenator Prototype with a Hemocompatible Blood Flow Path for Artificial Placenta Applications
Blauvelt, D. G.; Higgins, N.; De, B.; Goodin, M. S.; Wright, N.; Blaha, C.; Moyer, J.; Chui, B.; Baltazar, F.; Oishi, P.; Roy, S.
10.1101/2022.08.23.505025 — bioengineering — Posted on 2022-10-02
4224 MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner
Xie, G.; Lee, J.-E.; Senft, A. D.; Park, Y.-K.; Chakraborty, S.; Thompson, J. J.; Liu, C.; Macfarlan, T. S.; Rocha, P. P.; Peng, W.; Ge, K.
10.1101/2020.09.14.296558 — molecular biology — Posted on 2022-10-02
4226 Predicting enzyme substrate chemical structure with protein language models
Jinich, A.; Nazia, S. Z.; Tellez, A. V.; Rappoport, D.; AlQuraishi, M.; Rhee, K. Y.
10.1101/2022.09.28.509940 — microbiology — Posted on 2022-10-02
4230 Pump-less, recirculating organ-on-a-chip (rOoC) platform
Busek, M.; Aizenshtadt, A.; Koch, T.; Frank, A.; Delon, L.; Amirola-Martinez, M.; Golovin, A.; Dumas, C.; Stokowiec, J.; Gruenzner, S.; Melum, E.; Krauss, S.
10.1101/2022.09.06.506239 — bioengineering — Posted on 2022-10-01
4236 May mineral composition trigger or limit the protein content in soybean (Glycine max (L.) Merrill) seeds? Insights from a survey on 95 varieties cultivated in Brazil
Montanha, G. S.; Perez, L. C.; Brandao, J. R.; de Camargo, R. F.; Tavares, T. R.; de Almeida, E.; Pereira de Carvalho, H. W. W. P.
10.1101/2022.09.29.510200 — plant biology — Posted on 2022-10-01
4237 Trafficking dynamics of VEGFR1, VEGFR2, and NRP1 in human endothelial cells
Sarabipour, S.; Kinghorn, K.; Quigley, K. M.; Kovacs-Kasa, A.; Annex, B. H.; Bautch, V. L.; Mac Gabhann, F.
10.1101/2022.09.30.510412 — systems biology — Posted on 2022-10-01
4238 NHA1 is a cation/proton antiporter essential for the water-conserving functions of the rectal complex in Tribolium castaneum
Naseem, M. T.; Beaven, R.; Koyama, T.; Naz, S.; Su, M.; Leader, D.; Klaerke, D.; Calloe, K.; Denholm, B.; Halberg, K. V.
10.1101/2022.09.29.510179 — systems biology — Posted on 2022-10-01
4241 Genomic accordions may hold the key to Monkeypox Clade IIb's increased transmissibility
Monzon, S.; Varona, S.; Negredo, A.; Patino-Galindo, J. A.; Vidal-Freire, S.; Zaballos, A.; Orviz, E.; Ayerdi, O.; Munoz-Garcia, A.; Delgado-Iribarren, A.; Estrada, V.; Garcia, C.; Molero, F.; Sanchez, P.; Torres, M.; Vazquez, A.; Galan, J.-C.; Torres, I.; Causse del Rio, M.; Merino, L.; Lopez, M.; Galar, A.; Cardenoso, L.; Gutierrez, A.; Camacho, J.; Herrero, L.; Jimenez-Sancho, P.; Navarro-Rico, M. L.; Jado, I.; Kuhn, J.; Sanchez-Lockhart, M.; Di Paola, N.; Kugelman, J. R.; Giannetti, E.; Guerra, S.; Garcia-Sastre, A.; Palacios, G.; Cuesta, I.; Sanchez-Seco, M.
10.1101/2022.09.30.510261 — genomics — Posted on 2022-10-01
4242 Combining RADseq and contact zone analysis to decipher cryptic diversification in reptiles: insights from Acanthodactylus erythrurus (Reptilia: Lacertidae)
Doniol-Valcroze, P.; Rancilhac, L.; Brito, J. C.; Miralles, A.; Geniez, P.; Benoit, L.; Loiseau, A.; Leblois, R.; Dufresnes, C.; Crochet, P.-A.
10.1101/2022.09.30.510260 — genomics — Posted on 2022-10-01
4244 Horizontal transferred T-DNA and haplotype-based phylogenetic analysis uncovers the origin of sweetpotato
Yan, M.; Li, M.; Wang, Y.; Wang, X.; Moeinzadeh, M.-H.; Quispe-Huamanquispe, D. G.; Fan, W.; Wang, Y.; Nie, H.; Wang, Z.; Heider, B.; Jarret, R.; Kreuze, J. F.; Gheysen, G.; Wang, H.; Bock, R. F.; Vingron, M.; Yang, J.
10.1101/2022.09.30.510208 — evolutionary biology — Posted on 2022-10-01
4247 Murine macrophage choline metabolism underpins IL-4 polarization and RELMα up-regulation
Ghorbani, P.; Kim, S. Y.; Smith, T. K.; Minarrieta, L.; Kilgour, M. K.; Ilijevska, M.; Alecu, I.; Snider, S. A.; Margison, K. D.; Nunes, J. R.; Woo, D.; Pember, C.; O'Dwyer, C.; St-Pierre, J.; Bennett, S. A.; Nair, M. G.; Fullerton, M. D.
10.1101/2022.09.30.510305 — immunology — Posted on 2022-10-01
4249 Divergent and dominant anti-inflammatory effects of patient-derived anti-citrullinated protein antibodies (ACPA) in arthritis development
Raposo, B.; Afonso, M. G.; Israelsson, L.; Wähämaa, H.; Stalesen, R.; Wermeling, F.; Grönwall, C.; Rethi, B.; Klareskog, L.; Malmström, V.
10.1101/2022.09.30.510377 — immunology — Posted on 2022-10-01
4250 Subcutaneous BCG vaccination protects against streptococcal pneumonia via regulating innate immune responses in the lung
Kang, A.; Ye, G.; Singh, R.; Afkhami, S.; Bavananthasivam, J.; Luo, X.; Vaseghi-Shanjani, M.; Zganiacz, A.; Jeyanathan, M.; Xing, Z.
10.1101/2022.09.29.510220 — immunology — Posted on 2022-10-01
4254 Phenotypic and genomic comparison of human outbreak and cattle-associated Shiga toxin-producing Escherichia coli O157:H7
Peroutka-Bigus, N.; Nielsen, D. W.; Trachsel, J.; Mou, K.; Sharma, V. K.; Kudva, I. T.; Loving, C. L.
10.1101/2022.09.30.510420 — microbiology — Posted on 2022-10-01
4255 RNAi-mediated rheostat for dynamic control of AAV-delivered transgenes
Subramanian, M.; McIninch, J.; Zlatev, I.; Schlegel, M. K.; Kaittanis, C.; Nguyen, T.; Agarwal, S.; Racie, T.; Alvarado, M. A.; Wassarman, K.; Collins, T. S.; Chickering, T.; Brown, C. R.; Schmidt, K.; Castoreno, A. B.; Shulga Morskaya, S.; Stamenova, E.; Buckowing, K.; Berman, D.; Barry, J. D.; Bisbe, A.; Maier, M. A.; Fitzgerald, K.; Jadhav, V.
10.1101/2022.09.30.510386 — genomics — Posted on 2022-10-01
4257 Temporal Extracellular Vesicle Protein Changes following Intraarticular Treatment with Integrin α10β1-selected Mesenchymal Stem Cells in Equine Osteoarthritis
Clarke, E. J.; Johnson, E.; Caamano Gutierrez, E.; Andersen, C.; Berg, L.; Jenkins, R.; Lindegaard, C.; Uvebrant, K.; Lundgren-Akerlund, E.; Turlo, A.; James, V.; Jacobsen, S.; Peffers, M. J.
10.1101/2022.09.30.510176 — molecular biology — Posted on 2022-10-01
4258 A meta-analysis of the stony coral tissue loss disease microbiome finds key bacteria in lesions and unaffected tissue of diseased colonies
Rosales, S. M.; Huebner, L. K.; Evans, J. S.; Apprill, A.; Baker, A. C.; Becker, C. C.; Bellantuono, A. J.; Brandt, M. E.; Clark, A. S.; del Campo, J.; Dennison, C. E.; Huntley, N. E.; Kellogg, C. A.; Medina, M.; Meyer, J. L.; Muller, E. M.; Rodriguez-Lanetty, M.; Salerno, J. L.; Schill, W. W.; Shilling, E. N.; Stewart, J. M.; Voss, J. D.
10.1101/2022.09.30.510359 — microbiology — Posted on 2022-10-01
4259 16S rRNA sequencing for profiling microbial communities in idiopathic granulomatous mastitis
Ong, S. S.; Xu, J.; Sim, C. K.; Khng, A. J.; Ho, P. J.; Kwan, P. K. W.; Ravikrishnan, A.; Tan, K.-T. B.; Tan, Q. T.; Tan, E. Y.; Tan, S.-M.; Putti, T. C.; Lim, S. H.; Tang, E. L. S.; Nagarajan, N.; Karnani, N.; Li, J.; Hartman, M.
10.1101/2022.09.30.510425 — microbiology — Posted on 2022-10-01
4260 Actin cytoskeleton dynamics affect replication of Human Metapneumovirus
Rodriguez, P. E.; Gil, P. I.; Camara, J. A.; Camara, A.; Paglini, M. G.
10.1101/2022.09.30.510364 — microbiology — Posted on 2022-10-01
4261 High-content phenotypic screen to identify small molecule enhancers of parkin-dependent ubiquitination and mitophagy
Tufi, R.; Clark, E. H.; Hoshikawa, T.; Tsagkaraki, C.; Stanley, J.; Takeda, K.; Staddon, J. M.; Briston, T.
10.1101/2022.09.30.509127 — cell biology — Posted on 2022-10-01
4262 An Integrated Physiological, Cytology and Proteomics Reveals Network of Sugarcane Protoplasts Responses to Enzymolysis
Zhang, D.; Wang, R.; Xiao, J.; Zhu, S.; Li, X.; Han, S.; Li, Z.; Zhao, Y.; Shohag, M. J. I.; He, Z.; Li, S.
10.1101/2022.09.30.510375 — cell biology — Posted on 2022-10-01
4271 Use of Transient Transfection for cGMP Manufacturing of eOD-GT8 60mer, a Self-Assembling Nanoparticle Germline-Targeting HIV-1 Vaccine Candidate
Sharma, V. K.; Tsvetnitsky, V.; Menis, S.; Brower, E. T.; Sayeed, E.; Ackland, J.; Lombardo, A.; Hassell, T.; Schief, W. R.
10.1101/2022.09.30.510310 — biochemistry — Posted on 2022-10-01
4272 Dual states of Bmi1-expressing intestinal stem cells drive epithelial development and tissue regeneration
Smith, N. R.; Sengupta, S. K.; Conley, P.; Giske, N. R.; Klocke, C.; Walker, B. S.; McPhail, N.; Swain, J. R.; Yoo, Y. J.; Anderson, A. N.; Davies, P. S.; Sanati, N.; Nguyen, T. N.; Torkenczy, K.; Adey, A. C.; Fischer, J. M.; Wu, G.; Wong, M. H.
10.1101/2022.09.30.509798 — developmental biology — Posted on 2022-10-01
4274 Functionally distinct promoter classes initiate transcription via different mechanisms reflected in focused versus dispersed initiation patterns
Serebreni, L.; Pleyer, L.-M.; Haberle, V.; Hendy, O.; Vlasova, A.; Loubiere, V.; Nemcko, F.; Bergauer, K.; Roitinger, E.; Mechtler, K.; Stark, A.
10.1101/2022.09.30.509643 — molecular biology — Posted on 2022-10-01
4275 McIdas localizes at centrioles and controls centriole numbers through PLK4-dependent phosphorylation
Arbi, M.; Skamnelou, M.; Bournaka, S.; Zitouni, S.; Tsaridou, S.; Karayel, O.; Vasilopoulou, C. G.; Tsika, A. C.; Giakoumakis, N. N.; Spyroulias, G. A.; Mann, M.; Bettencourt-Dias, M.; Taraviras, S.; Lygerou, Z.
10.1101/2022.09.30.510086 — molecular biology — Posted on 2022-10-01
4277 Mechanisms of insertions at a DNA double-strand break
Min, J.; Zhao, J.; Zagelbaum, J.; Takahashi, S.; Cummings, P.; Schooley, A.; Dekker, J.; Gottesman, M. E.; Rabadan, R.; Gautier, J.
10.1101/2022.09.30.509517 — molecular biology — Posted on 2022-10-01
4279 Iterative immunostaining combined with expansion microscopy and image processing reveals nanoscopic network organization of nuclear lamina
Mantyla, E.; Montonen, T.; Azzari, L.; Mattola, S.; Hannula, M.; Vihinen-Ranta, M.; Hyttinen, J.; Vippola, M.; Foi, A.; Nymark, S.; Ihalainen, T. O.
10.1101/2022.09.27.509734 — molecular biology — Posted on 2022-10-01
4280 The structure of a Plasmodium vivax Tryptophan Rich Antigen suggests a lipid binding function for a pan-Plasmodium multi-gene family
Kundu, P.; Naskar, D.; McKie, S.; Dass, S.; Kanjee, U.; Introini, V.; Ferreira, M. U.; Duraisingh, M.; Deane, J. E.; Rayner, J. C.
10.1101/2022.09.30.510049 — microbiology — Posted on 2022-10-01
4282 Isotope-enrichment reveals active viruses follow microbial host dynamics during rewetting of a California grassland soil
Nicolas, A. M.; Sieradzki, E. T.; Pett-Ridge, J.; Banfield, J. F.; Taga, M. E.; Firestone, M. K.; Blazewicz, S. J.
10.1101/2022.09.30.510406 — microbiology — Posted on 2022-10-01
4283 Predicting enzyme substrate chemical structure with protein language models
Jinich, A.; Nazia, S. Z.; Tellez, A. V.; Rappoport, D.; Rhee, K. Y.; AlQuraishi, M.
10.1101/2022.09.28.509940 — microbiology — Posted on 2022-10-01
4285 Myelin-reactive B cells exacerbate the severity of CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner.
Fazazi, M. R.; Doss, P. M. I. A.; Pereira, R.; Fudge, N.; Regmi, A.; Akbar, I.; Yeola, A. P.; Mailhot, B.; Baillargeon, J.; Grenier, P.; Bertrand, N.; Lacroix, S.; Moore, C. S.; Rojas, O. L.; Rangachari, M.
10.1101/721696 — immunology — Posted on 2022-10-01
4287 βIII-Tubulin is a Brake on Extrinsic Cell-Death in Pancreatic Cancer
Kokkinos, J.; Sharbeen, G.; Ignacio, R. M. C.; Pandzic, E.; Youkhana, J.; Boyer, C.; Haghighi, K. S.; Gunawarman, M.; Goldstein, D.; Gebski, V.; Pajic, M.; Pitiyarachchi, O.; Davis, M. E.; Schulstad, G.; Arkell, O. S. M.; Kopecky, C.; Gonzales-Aloy, E.; Erkan, M.; Morton, J. P.; Kavallaris, M.; Gunning, P. W.; Hardeman, E. C.; Johns, A.; Gill, A. J.; Whan, R. M.; Mawson, A.; Australian Pancreatic Cancer Genome Initiative, ; McCarroll, J. A.; Phillips, P. A.
10.1101/2022.09.29.510034 — cancer biology — Posted on 2022-10-01
4289 Molecular view of ER membrane remodeling by the Sec61/TRAP translocon
Karki, S.; Javanainen, M.; Tranter, D.; Rehan, S.; Huiskonen, J. T.; Happonen, L.; Paavilainen, V.
10.1101/2022.09.30.510141 — biochemistry — Posted on 2022-10-01
4291 Theory and application of an improved species richness estimator
Tekwa, E. W.; Whalen, M. A.; Martone, P. T.; O'Connor, M. I.
10.1101/2022.05.02.490342 — ecology — Posted on 2022-10-01
4293 Transcriptional regulation and repressive condensates modulate a proliferative-invasive cellular switch in vivo
Medwig-Kinney, T. N.; Kinney, B. A.; Martinez, M. A. Q.; Yee, C.; Sirota, S. S.; Mullarkey, A. A.; Somineni, N.; Hippler, J.; Zhang, W.; Shen, K.; Hammell, C. M.; Pani, A. M.; Matus, D. Q.
10.1101/2022.09.30.510381 — developmental biology — Posted on 2022-10-01
4297 ES30L: A large subunit rRNA expansion segment enriched in mammals and birds
Hariharan, N.; Ghosh, S.; Nallan, A. N.; Ramesh, A.; Agashe, D.; Palakodeti, D.
10.1101/2022.09.30.510333 — molecular biology — Posted on 2022-10-01
4298 Thermophilic carboxylesterases from hydrothermal vents of the volcanic island of Ischia active on synthetic and biobased polymers and mycotoxins
Distaso, M. A.; Chernikova, T. N.; Bargiela, R.; Coscoln, C.; Stogios, P. J.; Gonzalez, J. L.; Lemak, S.; Khusnutdinova, A. N.; Plou, F. J.; Evdokimova, E.; Savchenko, A.; Lunev, E. A.; Yakimov, M. M.; Golyshina, O. V.; Ferrer, M.; Yakunin, A. F.; Golyshin, P. N.
10.1101/2022.09.17.508236 — microbiology — Posted on 2022-10-01
4300 Asymmetric Signaling Across the Hierarchy of Cytoarchitecture within the Human Connectome
Parkes, L.; Kim, J. Z.; Stiso, J.; Calkins, M. E.; Cieslak, M.; Gur, R. E.; Gur, R. C.; Moore, T. M.; Ouellet, M.; Roalf, D. R.; Shinohara, R. T.; Wolf, D. H.; Satterthwaite, T. D.; Bassett, D. S.
10.1101/2022.05.13.491642 — neuroscience — Posted on 2022-10-01
4301 Immature olfactory sensory neurons provide behaviourally relevant sensory input to the olfactory bulb
Huang, J. S.; Kunkhyen, T.; Rangel, A. N.; Brechbill, T. R.; Gregory, J. D.; Winson-Bushby, E. D.; Liu, B.; Avon, J. T.; Muggleton, R. J.; Cheetham, C. E. J.
10.1101/2021.01.06.425578 — neuroscience — Posted on 2022-10-01
4302 Repetitive mild traumatic brain injury impairs resting state fMRI connectivity and alters protein profile signaling networks
Ravi, S.; Criado-Marrero, M.; Barroso, D.; Braga, I. M.; Bolen, M.; Rubinovich, U.; Hery, G. P.; Grudny, M. M.; Koren, J.; Prokop, S.; Febo, M.; Abisambra, J. F.
10.1101/2022.09.21.508917 — neuroscience — Posted on 2022-10-01
4303 Hybrid Synthesis of bioplastics polyhydroxybutyrate from carbon dioxide
Zhang, J.; Liu, D.; Liu, Y.; Chu, H.; Cheng, J.; Zhao, H.; Fu, S.; Liu, H.; Fu, Y.; Ma, Y.; Jiang, H.
10.1101/2022.09.30.510340 — synthetic biology — Posted on 2022-10-01
4304 Aberrant DNA methylation distorts developmental trajectories in atypical teratoid/rhabdoid tumors
Pekkarinen, M.; Nordfors, K.; Uusi-Makela, J.; Kytola, V.; Rauhala, M.; Urhonen, H.; Hayrynen, S.; Afyounian, E.; Yli-Harja, O.; Zhang, W.; Helen, P.; Lohi, O.; Haapasalo, H.; Haapasalo, J.; Nykter, M.; Kesseli, J.; Rautajoki, K. J.
10.1101/2022.03.14.483566 — cancer biology — Posted on 2022-10-01
4306 Residual Complex I activity supports glutamate catabolism and mtSLP via canonical Krebs cycle activity during acute anoxia without OXPHOS
Ravasz, D.; Bui, D.; Nazarian, S.; Pallag, G.; Karnok, N.; Roberts, J.; Tennant, D. A.; Greenwood, B.; Kitayev, A.; Hill, C.; Komlodi, T.; Doerrier, C.; Gnaiger, E.; Kiebish, M. A.; Raska, A.; Kolev, K.; Czumbel, B.; Narain, N. R.; Seyfried, T. N.; Chinopoulos, C.
10.1101/2022.09.26.509156 — biochemistry — Posted on 2022-10-01
4307 Engineered RecA constructs reveal the minimal SOS activation complex
Cory, M. B.; Li, A.; Hurley, C. M.; Hostetler, Z. M.; Venkatesh, Y.; Jones, C. M.; Petersson, E. J.; Kohli, R. M.
10.1101/2022.09.30.510415 — biochemistry — Posted on 2022-10-01
4312 Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation
Buglak, D. B.; Kulikauskas, M. R.; Liu, Z.; Gold, A. L.; Marvin, A. P.; Burciu, A.; Tanke, N. T.; Ricketts, S. N.; Kinghorn, K.; Oatley, M.; Johnson, B. N.; Bougaran, P.; Shiau, C. E.; Rogers, S. L.; Bautch, V. L.
10.1101/2021.08.11.455980 — cell biology — Posted on 2022-10-01
4314 A coordinated transcriptional switching network mediates antigenic variation of human malaria parasites
Zhang, X.; Florini, F.; Visone, J. E.; Leonardi, I.; Gross, M. R.; Patel, V.; Deitsch, K. W.
10.1101/2022.09.29.510131 — microbiology — Posted on 2022-10-01
4315 Influenza A Virus Exacerbates Group A Streptococcus Infection and Thwarts Anti-bacterial Inflammatory Responses in Murine Macrophages
Aleith, J.; Brendel, M.; Weipert, E.; Müller, M.; Schultz, D.; Karen Methling, Michael Lalk, Ulrike Blohm, Alexander Schäfer, Bernd Kreikemeyer, ; Müller-Hilke, B.
10.1101/2022.03.10.483890 — immunology — Posted on 2022-10-01
4317 Motivated for near impossibility: How task type and reward modulate task enjoyment and the striatal activation for extremely difficult task.
Sakaki, M.; Meliss, S.; Murayama, K.; Yomogida, Y.; Matsumori, K.; Sugiura, A.; Matsumoto, M.; Matsumoto, K.
10.1101/828756 — neuroscience — Posted on 2022-10-01
4318 Predictive coding in ASD: reduced adaptability of priors to environmental changes
Shi, Z.; Theisinger, L.; Allenmark, F.; Pistorius, R.; Mueller, H. J.; Falter-Wagner, C.
10.1101/2022.01.21.477218 — neuroscience — Posted on 2022-10-01
4320 Alzheimer's-associated upregulation of mitochondria-associated ER membranes after traumatic brain injury
Agrawal, R. R.; Larrea, D.; Xu, Y.; Shi, L.; Zirpoli, H.; Cummins, L. G.; Emmanuele, V.; Song, D.; Yun, T. D.; Macaluso, F. P.; Min, W.; Kernie, S. G.; Deckelbaum, R. J.; Area-Gomez, E.
10.1101/2020.11.13.381756 — neuroscience — Posted on 2022-10-01
4321 Unidirectional Single-File Transport of Full-Length Proteins Through a Nanopore
Yu, L.; Kang, X.; Li, F.; Mehrafrooz, B.; Makhamreh, A.; Fallahi, A.; Foster, J.; Aksimentiev, A.; Chen, M.; Wanunu, M.
10.1101/2021.09.28.462155 — biophysics — Posted on 2022-10-01