bioRxiv directory

Kim, E.-J.; Kim, J. Y.; Kim, S.-O.; Ham, S. W.; Choi, S.-H.; Hong, N.; Park, M. G.; Jang, J.; Seo, S.; Lee, K.; Jeong, H. J.; Kim, S. J.; Jeong, S.; Min, K.; Kim, S.-C.; Jin, X.; Kim, S. H.; Kim, S.-H.; Kim, H.

10.1101/2021.03.31.437839 — molecular biology — Posted on 2021-03-31

11 Modulating the activities of chloroplasts and mitochondria promotes ATP production and plant growth

Voon, C. P.; Law, Y.-S.; Guan, X.; Xu, Z.; Lim, S.-L.; Chu, W.-T.; Zhang, R.; Sun, F.; Labs, M.; Pribil, M.; Leister, D.; Hronkova, M.; Kubasek, J.; Cui, Y.; Jiang, L.; Tsuyama, M.; Gardestrom, P.; Tikkanen, M.; Lim, B. L.

10.1101/2020.09.09.289967 — plant biology — Posted on 2021-03-31

12 Emerging SARS-CoV-2 mutation hotspots associated with clinical outcomes

Pang, X.; Li, P.; Zhang, L.; Que, L.; Dong, M.; Wang, Q.; Wei, Y.; Xie, B.; Xie, X.; Li, L.; Yin, C.; Wei, L.; Zhou, Q.; Li, Y.; Yu, L.; Li, W.; Mo, Z.; Leng, J.; Hu, Y.

10.1101/2021.03.31.437666 — bioinformatics — Posted on 2021-03-31

13 Differential expression of single-cell RNA-seq data using Tweedie models

Mallick, H.; Chatterjee, S.; Chowdhury, S.; Chatterjee, S.; Rahnavard, A.; Hicks, S. C.

10.1101/2021.03.28.437378 — bioinformatics — Posted on 2021-03-31

14 A mechanistic basis for understanding the dual activities of the bifunctional Azotobacter vinelandii mannuronan C-5 epimerase and alginate lyase AlgE7

Gaardlos, M.; Heggeset, T. M. B.; Tondervik, A.; Teze, D.; Svensson, B.; Ertesvag, H.; Sletta, H.; Aachmann, F. L.

10.1101/2021.03.31.437818 — biochemistry — Posted on 2021-03-31

15 Large uncertainty in individual PRS estimation impacts PRS-based risk stratification

Ding, Y.; Hou, K.; Burch, K. S.; Lapinska, S.; Prive, F.; Vilhjalmsson, B. J.; Sankararaman, S.; Pasaniuc, B.

10.1101/2020.11.30.403188 — genomics — Posted on 2021-03-31

16 An integrative skeletal and paleogenomic analysis of prehistoric stature variation suggests relatively reduced health for early European farmers

Marciniak, S.; Bergey, C.; Silva, A. M.; Hałuszko, A.; Furmanek, M.; Veselka, B.; Veleminsky, P.; Vercellotti, G.; Wahl, J.; Zarina, G.; Longhi, C.; Kolar, J.; Garrido-Pena, R.; Flores-Fernandez, R.; Herrero-Corral, A. M.; Simalcsik, A.; Müller, W.; Sheridan, A.; Miliauskiene, Z.; Jankauskas, R.; Moiseyev, V.; Köhler, K.; Kiraly, A.; Gamarra, B.; Cheronet, O.; Szeverenyi, V.; Kiss, V.; Szeniczey, T.; Kiss, K.; Zoffmann, Z. K.; Koos, J.; Hellebrandt, M.; Domboroczki, L.; Virag, C.; Novak, M.; Reich, D. E.; Hajdu, T.; von Cramon-Taubadel, N.; Pinhasi, R.; Perry, G. H.

10.1101/2021.03.31.437881 — genomics — Posted on 2021-03-31

17 Contact-tracing in cultural evolution: a Bayesian mixture model to detect geographic areas of language contact

Ranacher, P.; Neureiter, N.; van Gijn, R.; Sonnenhauser, B.; Escher, A.; Weibel, R.; Muysken, P.; Bickel, B.

10.1101/2021.03.31.437731 — evolutionary biology — Posted on 2021-03-31

18 Predicting skeletal stature using ancient DNA

Cox, S. L.; Moots, H.; Stock, J. T.; Shbat, A.; Bitarello, B. D.; Haak, W.; Rosenstock, E.; Ruff, C. B.; Mathieson, I.

10.1101/2021.03.31.437877 — evolutionary biology — Posted on 2021-03-31

19 Symbiodiniaceae conduct under natural bleaching stress during advanced gametogenesis stages of a mesophotic coral

Eyal, G.; Eyal-Shaham, L.; Loya, Y.

10.1101/2021.03.25.437087 — ecology — Posted on 2021-03-31

20 Physical properties of the cytoplasm modulate the rates of microtubule polymerization and depolymerization

Molines, A. T.; Lemiere, J.; Gazzola, M.; Steinmark, I. E.; Edrington, C. H.; Hsu, C.-T.; Suhling, K.; Goshima, G.; Holt, L. J.; Thery, M.; Brouhard, G.; Chang, F.

10.1101/2020.10.27.352716 — cell biology — Posted on 2021-03-31

21 Large-scale identification of protein histidine methylation in human cells

Jakobsson, M. E.; Kapell, S.

10.1101/2021.03.31.437816 — molecular biology — Posted on 2021-03-31

22 JAG1 intracellular domain acts as a transcriptional cofactor that forms an oncogenic transcriptional complex with DDX17/SMAD3/TGIF2

10.1101/2021.03.31.437839 — molecular biology — Posted on 2021-03-31

23 BacAnt: A Combination Annotation Server for Bacterial DNA Sequences to Identify Antibiotic Resistance Genes, Integrons, and Transposable Elements.

Hua, X.; Liang, Q.; Deng, M.; He, J.; Wang, M.; Hong, W.; Wu, J.; Lu, B.; Leptihn, S.; Yu, Y.; Chen, H.

10.1101/2020.09.05.284273 — microbiology — Posted on 2021-03-31

24 Mechanisms involved in the active secretion of CTX-M-15 β-lactamase by pathogenic E. coli ST131

Rangama, S.; Lidbury, I. D. E. A.; Holden, J. M.; Borsetto, C.; Murphy, A. R. J.; Hawkey, P. M.; Wellington, E. M. H.

10.1101/2021.03.31.437630 — microbiology — Posted on 2021-03-31

25 Balance training improves feedback control of perturbed balance in older adults

Alizadehsaravi, L.; Bruijn, S. M.; van Dieen, J. H.

10.1101/2021.03.31.437824 — neuroscience — Posted on 2021-03-31

26 Reduced anterior cingulate cortex volume induced by chronic stress correlates with increased behavioral emotionality and decreased synaptic puncta density

Misquitta, K. A.; Miles, A.; Prevot, T. D.; Knoch, J. K.; Fee, C.; Newton, D. F.; Ellegood, J.; Lerch, J. P.; Sibille, E.; Nikolova, Y.; Banasr, M.

10.1101/2020.08.31.275750 — neuroscience — Posted on 2021-03-31

27 Perception of effort during an isometric contraction is influenced by prior muscle lengthening or shortening

Kozlowski, B.; Pageaux, B.; Hubbard, E. F.; St. Peters, B.; Millar, P. J.; Power, G. A.

10.1101/2021.03.29.437599 — neuroscience — Posted on 2021-03-31

28 A Whole-Brain Map and Assay Parameter Analysis of Mouse VTA Dopaminergic Activation

Ioanas, H.-I.; Saab, B. J.; Rudin, M.

10.1101/2020.04.03.023648 — neuroscience — Posted on 2021-03-31

29 The sleeping brain switches between working memory and long-term memory processing.

Chen, P.-C.; Niknazar, H.; Alaynick, W. A.; Whitehurst, L. N.; Mednick, S. C.

10.1101/2021.03.31.437952 — neuroscience — Posted on 2021-03-31

30 Whole-Brain Longitudinal Profiling of Serotonergic Reuptake Inhibition

Ioanas, H.-I.; Saab, B. J.; Rudin, M.

10.1101/2020.08.10.243899 — neuroscience — Posted on 2021-03-31

31 Lysophosphatidyl-choline 16:0 mediates persistent joint pain through Acid-Sensing Ion Channel 3: preclinical and clinical evidences

Jacquot, F.; Khoury, S.; Labrum, B.; Delanoe, K.; Pidoux, L.; Barbier, J.; Delay, L.; Bayle, A.; Aissouni, Y.; Barriere, D. A.; Kultima, K.; Freyhult, E.; Hugo, A.; Kosek, E.; Ahmed, A. S.; Jurczak, A.; Lingueglia, E.; Svensson, C. I.; Breuil, V.; Ferreira, T.; Marchand, F.; Deval, E.

10.1101/2021.03.29.437487 — neuroscience — Posted on 2021-03-31

32 Structure Can Predict Function in the Human Brain: A Graph Neural Network Deep Learning Model of Functional Connectivity and Centrality based on Structural Connectivity

Neudorf, J.; Kress, S.; Borowsky, R.

10.1101/2021.03.15.435531 — neuroscience — Posted on 2021-03-31

33 PRSS2 stimulates tumor growth by remodeling the TME via repression of Tsp1

Sui, L.; Wang, S.; Ganguly, D.; El Rayes, T.; Askeland, C.; Borretzen, A.; Zhou, K.; Sim, D.; Halvorsen, O. J.; Knutsvik, G.; Aziz, S.; Haukaas, S.; Foulkes, W. D.; Bielenberg, D. R.; Ziemys, A.; Mittall, V.; Brekken, R. A.; Akslen, L. A.; Watnick, R. S.

10.1101/2021.03.23.436667 — cancer biology — Posted on 2021-03-31

34 scAmpi - A versatile pipeline for single-cell RNA-seq analysis from basics to clinics

Bertolini, A.; Prummer, M.; Tuncel, M. A.; Menzel, U.; Rosano-Gonzalez, M. L.; Kuipers, J.; Stekhoven, D. J.; Tumor Profiler consortium, ; Beerenwinkel, N.; Singer, F.

10.1101/2021.03.25.437054 — bioinformatics — Posted on 2021-03-31

35 Genome-wide survey of odorant-binding proteins in the dwarf honey bee Apis florea

Mam, B.; Karpe, S. D.; Sowdhamini, R.

10.1101/2021.02.25.432941 — bioinformatics — Posted on 2021-03-31

36 The SpliZ generalizes "Percent Spliced In" to reveal regulated splicing at single-cell resolution

Olivieri, J. E.; Dehghannasiri, R.; Salzman, J.

10.1101/2020.11.10.377572 — bioinformatics — Posted on 2021-03-31

37 Differential mutational profile of SARS-CoV-2 proteins across deceased and asymptomatic patients

Laskar, R.; Ali, S.

10.1101/2021.03.31.437815 — bioinformatics — Posted on 2021-03-31

38 CRISPR-mediated knock-in of transgenes into the malaria vector Anopheles funestus

Quinn, C.; Anthousi, A.; Wondji, C.; Nolan, T.

10.1101/2021.03.31.437891 — genetics — Posted on 2021-03-31

39 Decreased adaptation at human disease genes as a possible consequence of interference between advantageous and deleterious variants

Di, C.; Salazar Tortosa, D.; Lauterbur, M. E.; Enard, D.

10.1101/2021.03.31.437959 — evolutionary biology — Posted on 2021-03-31

40 Taking full advantage of modelling to better assess environmental risk due to xenobiotics

Charles, S.; Ratier, A.; Baudrot, V.; Multari, G.; Wu, D.; Siberchicot, A.; Lopes, C.

10.1101/2021.03.24.436474 — ecology — Posted on 2021-03-31

41 A tyrosine-based trafficking signal in the simian immunodeficiency virus envelope cytoplasmic domain is strongly selected for in pathogenic SIV infection

Lawrence, S.; Elser, S. E.; Torben, W.; Blair, R. V.; Pahar, B.; Aye, P. P.; Schiro, F.; Szeltner, D.; Doyle-Meyers, L. A.; Haggarty, B.; Jordan, A. O.; Romano, J.; Alvarez, X.; O'Connor, D. H.; Wiseman, R. W.; Fennessey, C. M.; Li, Y.; Piatak, M.; Lifson, J. D.; LaBranche, C. C.; Lackner, A. A.; Keele, B. F.; Maness, N. J.; Marsh, M.; Hoxie, J. A.

10.1101/2021.03.31.437834 — cell biology — Posted on 2021-03-31

42 Molecular characterization of a complex of Apoptosis Inducing Factor 1 (AIFM1) with cytochrome c oxidase of the mitochondrial respiratory chain

Hevler, J. F.; Zenezini Chiozzi, R.; Cabrera-Orefice, A.; Brandt, U.; Arnold, S.; Heck, A. J. R.

10.1101/2021.03.31.437858 — molecular biology — Posted on 2021-03-31

43 Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling

van der Stel, A.-X.; Gordon, E. R.; Sengupta, A.; Martinez, A. K.; Klepacki, D.; Perry, T. N.; Herrero del Valle, A.; Vazquez-Laslop, N.; Sachs, M. S.; Cruz-Vera, L. R.; Innis, C. A.

10.1101/2021.03.31.437805 — molecular biology — Posted on 2021-03-31

44 Virulence shift in a sexual clade of Type X Toxoplasma infecting Southern Sea Otters

Kennard, A.; Miller, M. A.; Khan, A.; Quinones, M.; Miller, N.; Sundar, N.; James, E. R.; Roos, D. S.; Conrad, P. A.; Grigg, M. E.

10.1101/2021.03.31.437793 — molecular biology — Posted on 2021-03-31

45 Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

Rosendahl, A.-H.; Monnius, M.; Laitala, A.; Railo, A.; Miinalainen, I.; Heljasvaara, R.; Mäki, J. M.; Myllyharju, J.

10.1101/2021.03.31.437126 — molecular biology — Posted on 2021-03-31

46 Unprecedented Protein Divergence within a T3SS Family

Madkour, A.; Almessiry, B. K. M.; Gonzalez-Pedrajo, B.; Kenny, B.

10.1101/2021.03.31.437910 — microbiology — Posted on 2021-03-31

47 A nascent polypeptide sequence modulates DnaA translation elongation in response to nutrient availability

Felletti, M.; Romilly, C.; Wagner, G.; Jonas, K.

10.1101/2021.03.31.437742 — microbiology — Posted on 2021-03-31

48 A Broadly Conserved Deoxycytidine Deaminase Protects Bacteria from Phage Infection

Severin, G. B.; Hsueh, B. Y.; Elg, C. A.; Dover, J. A.; Rhoades, C. R.; Wessel, A. J.; Ridenhour, B. J.; Top, E. M.; Ravi, J.; Parent, K. N.; Waters, C. M.

10.1101/2021.03.31.437871 — microbiology — Posted on 2021-03-31

49 Candida albicans enhances the progression of oral squamous cell cancrinoma in vitro and in vivo

Vadovics, M.; Igaz, N.; Alfoldi, R.; Rakk, D.; Veres, E.; Szucs, B.; Horvath, M.; Toth, R.; Szucs, A.; Horvath, P.; Tiszlavicz, L.; Vagvolgyi, C.; Nosanchuk, J.; Szekeres, A.; Kiricsi, M.; Puskas, L.; Gacser, A.

10.1101/2021.03.31.437836 — microbiology — Posted on 2021-03-31

50 Single-Cell Transcriptomic Analysis of Livers During NLRP3 Inflammasome Activation Reveals a Novel Immune Niche

Calcagno, D. M.; Chu, A.; Gaul, S.; Taghdiri, N.; Toomu, A.; Leszczynska, A.; Kaufmann, B.; Wree, A.; Geisler, L.; Hoffman, H. M.; Feldstein, A. E.; King, K. R.

10.1101/2021.03.31.437725 — immunology — Posted on 2021-03-31

51 Neural basis of functional ultrasound signals

Nunez-Elizalde, A. O.; Krumin, M.; Bai Reddy, C.; Montaldo, G.; Urban, A.; Harris, K. D.; Carandini, M.

10.1101/2021.03.31.437915 — neuroscience — Posted on 2021-03-31

52 Ankle muscles activate: mediolateral center of pressure control ensures stable gait

van Leeuwen, A. M.; van Dieen, J. H.; Daffertshofer, A.; Bruijn, S. M.

10.1101/2021.03.31.437904 — neuroscience — Posted on 2021-03-31

53 Information theoretic approaches to deciphering the neural code with functional fluorescence imaging

Climer, J. R.; Dombeck, D. A.

10.1101/2020.06.03.131870 — neuroscience — Posted on 2021-03-31

54 A model of the reference frame of the ventriloquism aftereffect

Loksa, P.; Kopco, N.

10.1101/2021.03.31.437664 — neuroscience — Posted on 2021-03-31

55 Antagonistic inhibitory subnetworks control cooperation and competition across cortical space

Mossing, D. P.; Veit, J.; Palmigiano, A.; Miller, K. D.; Adesnik, H.

10.1101/2021.03.31.437953 — neuroscience — Posted on 2021-03-31

56 A new method for obtaining bankable and expandable adult-like microglial cells

You, M.-J.; Rim, C.; Kang, Y.-J.; Kwon, M.

10.1101/2021.03.31.437811 — neuroscience — Posted on 2021-03-31

57 Differences in Regional Grey Matter Volume Predict the Extent to which Openness influences Judgments of Beauty and Pleasantness of Interior Architectural Spaces

Skov, M.; Vartanian, O.; Navarrete, G.; Modrono, C.; Chatterjee, A.; Leder, H.; Gonzalez-Mora, J. L.; Nadal, M.

10.1101/2021.03.31.437827 — neuroscience — Posted on 2021-03-31

58 Understanding Others Requires Right Temporoparietal and Inferior Frontal Regions

Schnur, T.; Ding, J.; Blake, M.

10.1101/2021.03.31.437941 — neuroscience — Posted on 2021-03-31

59 Robust Rhythmogenesis via Spike Timing Dependent Plasticity

Socolovsky, G.; Shamir, M.

10.1101/2020.07.23.217026 — neuroscience — Posted on 2021-03-31

60 Global Temporal Movement Control

Schlichting, N.; Kartashova, T.; Wiesing, M.; Zimmermann, E.

10.1101/2021.03.31.437803 — neuroscience — Posted on 2021-03-31

61 An Optimized Registration Workflow and Standard Geometric Space for Small Animal Brain Imaging

Ioanas, H.-I.; Marks, M.; Zerbi, V.; Yanik, M. F.; Rudin, M.

10.1101/619650 — neuroscience — Posted on 2021-03-31

62 Autonomic/Central Coupling during Daytime Sleep Differs between Older and Younger People

Chen, P.-C.; Simon, K. N.; Sattari, N.; Whitehurst, L. N.; Mednick, S. C.

10.1101/2020.09.22.297184 — neuroscience — Posted on 2021-03-31

63 Impact of fenbendazole resistance in Ascaridia dissimilis on the economics of production in turkeys

Collins, J.; Jordan, B.; Vidyashankar, A.; Jimenez Castro, P.; Kaplan, R. M.

10.1101/2021.03.30.437784 — zoology — Posted on 2021-03-31

64 Mobius Assembly for Plant Systems highlights promoter-terminator interaction in gene regulation

Andreou, A. I.; Nirkko, J.; Villarreal, M. O.; Nakayama, N.

10.1101/2021.03.31.437819 — synthetic biology — Posted on 2021-03-31

65 Quantification of durable CRISPR-based gene silencing activity

Nakamura, M.; Ivec, A.; Gao, Y.; Qi, L. S.

10.1101/2021.03.31.436355 — synthetic biology — Posted on 2021-03-31

66 A spatial multi-scale fluorescence microscopy toolbox discloses entry checkpoints of SARS-CoV-2 variants in VeroE6 cells

Storti, B.; Quaranta, P.; Di Primio, C.; Clementi, N.; Spezia, P. G.; Carnicelli, V.; Lottini, G.; Paolini, E.; Freer, G.; Lai, M.; Costa, M.; Beltram, F.; Diaspro, A.; Pistello, M.; Zucchi, R.; Bianchini, P.; Signore, G.; Bizzarri, R.

10.1101/2021.03.31.437907 — biophysics — Posted on 2021-03-31

67 Linking Diabetes mellitus to SARS-CoV-2 infection through differential targeting of the microRNAs in the Pancreas tissue

Bhavya, ; Pathak, E.; Mishra, R.

10.1101/2021.03.31.437823 — genomics — Posted on 2021-03-31

68 Comparative population genetic structure of two ixodid tick species (Ixodes ovatus and Haemaphysalis flava) in Niigata Prefecture, Japan

Regilme, M. A. F.; Sato, M.; Tamura, T.; Arai, R.; Sato, M. O.; Ikeda, S.; Gamboa, M.; Monaghan, M. T.; Watanabe, K.

10.1101/862904 — genetics — Posted on 2021-03-31

69 HuConTest: Testing human contamination in great ape samples

Kuhlwilm, M.; Fontsere, C.; Han, S.; Alvarez-Estape, M.; Marques-Bonet, T.

10.1101/2021.03.30.437753 — evolutionary biology — Posted on 2021-03-31

70 Impact of pubertal onset on region-specific Esr2 expression

Drzewiecki, C. M.; Sellinger, E. P.; Juraska, J. M.

10.1101/2021.03.31.437916 — neuroscience — Posted on 2021-03-31

71 Functional architecture of the aging brain

Setton, R.; Mwilambwe-Tshilobo, L.; Girn, M.; Lockrow, A. W.; Baracchini, G.; Lowe, A. J.; Cassidy, B. N.; Li, J.; Luh, W.-M.; Bzdok, D.; Leahy, R. M.; Ge, T.; Margulies, D. S.; Misic, B.; Bernhardt, B. C.; Stevens, W. D.; De Brigard, F.; Kundu, P.; Turner, G. R.; Spreng, R. N.

10.1101/2021.03.31.437922 — neuroscience — Posted on 2021-03-31

72 Robust and tunable signal processing in mammalian cells via engineered covalent modification cycles

Jones, R. D.; Qian, Y.; Ilia, K.; Wang, B.; Laub, M. T. T.; Del Vecchio, D.; Weiss, R.

10.1101/2021.03.30.437779 — synthetic biology — Posted on 2021-03-31

73 An automated feeding system for the African killifish reveals effects of dietary restriction on lifespan and allows scalable assessment of associative learning

McKay, A.; Hu, C.-K.; Chen, S.; Bedbrook, C. N.; Thielvoldt, M.; Wyss-Coray, T.; Brunet, A.

10.1101/2021.03.30.437790 — physiology — Posted on 2021-03-31

74 Gene name errors: lessons not learned

Abeysooriya, M.; Soria, M.; Kasu, M. S.; Ziemann, M.

10.1101/2021.03.30.437702 — genomics — Posted on 2021-03-31

75 Inhibition of MRN activity by a telomere protein motif

Bianchi, A.; Carr, A.; Cejka, P.; Cannavo, E.; Foster, W.; Smith, C.; Maddalena, M.; Chahwan, C.; Watson, A.; Khayat, F.; Alshmery, M.

10.1101/2021.03.30.437761 — genetics — Posted on 2021-03-31

76 Microbial rhodopsins are increasingly favored over chlorophyll in High Nutrient Low Chlorophyll waters

Hassanzadeh, B.; Thomson, B.; Deans, F.; Wenley, J.; Lockwood, S.; Currie, K.; Morales, S.; Steindler, L.; Sanudo-Wilhelmy, S.; Baltar, F.; Gomez-Consarnau, L.

10.1101/2021.03.30.437613 — ecology — Posted on 2021-03-31

77 Temporal regulation of green and red cone specification in human retinas and retinal organoids

Hadyniak, S. E.; Eldred, K. C.; Brenerman, B.; Hussey, K. A.; McCoy, R. C.; Sauria, M. E. G.; Kuchenbecker, J. A.; Neitz, M.; Neitz, J.; Taylor, J.; Johnston, R. J.

10.1101/2021.03.30.437763 — developmental biology — Posted on 2021-03-31

78 Genomic Analysis of Human Noroviruses Using Hybrid Illumina-Nanopore Data

Flint, A.; Reaume, S.; Harlow, J.; Hoover, E.; Weedmark, K. A.; Nasheri, N.

10.1101/2021.03.30.437798 — microbiology — Posted on 2021-03-31

79 In silico analysis of cis-elements and identification of transcription factors putatively involved in the regulation of the OAS cluster genes SDI1 and SDI2

Rakpenthai, A.; Apodiakou, A.; Whitcomb, S. J.; Hoefgen, R.

10.1101/2021.03.30.437644 — plant biology — Posted on 2021-03-31

80 Design principles of collateral sensitivity-based dosing strategies

Aulin, L. B. S.; Liakopoulos, A.; van der Graaf, P. H.; Rozen, D. E.; van Hasselt, J. G. C.

10.1101/2021.03.31.437927 — pharmacology and toxicology — Posted on 2021-03-31

81 Differential heating of metal nanostructures by radio frequencies: a theoretical study

Rommelfanger, N. J.; Ou, Z.; Keck, C. H. C.; Hong, G.

10.1101/2021.03.31.437926 — biophysics — Posted on 2021-03-31

82 OME-NGFF: scalable format strategies for interoperable bioimaging data

Moore, J.; Allan, C.; Besson, S.; Burel, J.-m.; Diel, E.; Gault, D.; Kozlowski, K.; Lindner, D.; Linkert, M.; Manzt, T.; Moore, W.; Tischer, C.; Swedlow, J. R.

10.1101/2021.03.31.437929 — bioinformatics — Posted on 2021-03-31

83 Tunable human myocardium derived decellularized extracellular matrix for 3D bioprinting and cardiac tissue engineering

Basara, G.; Ozcebe, S. G.; Ellis, B. W.; Zorlutuna, P.

10.1101/2021.03.30.437600 — bioengineering — Posted on 2021-03-31

84 CanDIG: Secure Federated Genomic Queries and Analyses Across Jurisdictions

Dursi, L. J.; Bozoky, Z.; de Borja, R.; Li, J.; Bujold, D.; Lipski, A.; Rashid, S. F.; Sethi, A.; Memon, N.; Naidoo, D.; Coral-Sasso, F.; Wong, M.; Quirion, P.-O.; Lu, Z.; Agarwal, S.; Pavlov, K.; Ponomarev, A.; Husic, M.; Pace, K.; Palmer, S. L.; Grover, S. A.; Hakgor, S.; Siu, L. L.; Malkin, D.; Virtanen, C.; Pugh, T. J.; Jacques, P.-E.; Joly, Y.; Jones, S. J. M.; Bourque, G.; Brudno, M.

10.1101/2021.03.30.434101 — genomics — Posted on 2021-03-31

85 Chromatin accessibility changes induced by the microbial metabolite butyrate reveal possible mechanisms of anti-cancer effects

Durrant, M. G.; Fremin, B. G.; Cribas, E.; Montgomery, S. B.; Bhatt, A. S.

10.1101/2021.03.30.437582 — genomics — Posted on 2021-03-31

86 Extensive variation in the mouse intelectin gene family: recent duplications, deletions and inactivating variants result in diversity in laboratory strains

Almalki, F.; Nonnecke, E. B.; Castillo, P. A.; Bevin-Holder, A.; Ullrich, K. K.; Lönnerdal, B.; Hollox, E. J.; Odenthal-Hesse, L.; Bevins, C. L.

10.1101/2021.03.31.437930 — genetics — Posted on 2021-03-31

87 Novel insights into joint estimations of demography, mutation rate, and selection using UV sex chromosomes

Carey, S. B.; Peniston, J. H.; Payton, A. C.; Kim, M.; Lipzen, A.; Bauer, D.; Lail, K.; Daum, C.; Barry, K.; Jenkins, J.; Grimwood, J.; Schmutz, J.; McDaniel, S. F.

10.1101/2021.03.30.437085 — evolutionary biology — Posted on 2021-03-31

88 Broad variation in rates of polyploidy and dysploidy across flowering plants is correlated with lineage diversification

Zhan, S. H.; Otto, S. P.; Barker, M. S.

10.1101/2021.03.30.436382 — evolutionary biology — Posted on 2021-03-31

89 Short-interval reburns in the boreal forest alter soil bacterial communities, reflecting increased pH and poor conifer seedling establishment

Woolet, J.; Whitman, E.; Parisien, M.-A.; Thompson, D. K.; Flannigan, M. D.; Whitman, T.

10.1101/2021.03.31.437944 — ecology — Posted on 2021-03-31

90 Hypsugo stubbei sp. nov., a novel cryptic bat species of the genus Hypsugo (Vespertilionidae, Chiroptera, Mammalia) from Mongolia. Results of the Mongolian-German Biological Expeditions Since 1962, No. 347.

Dolch, D.; Stubbe, M.; Batsaikhan, N.; Stubbe, A.; Steinhauser, D.

10.1101/2021.03.30.437544 — ecology — Posted on 2021-03-31

91 Deep conservation of Hid-like RHG gene family homologs in winged insects

Friedrich, M.

10.1101/2021.03.30.437773 — developmental biology — Posted on 2021-03-31

92 Multi-omics approach to identify bacterial polyynes and unveil their antifungal mechanism against Candida albicans

Lin, C.-C.; Hoo, S. Y.; Lin, C.; Huang, K.-F.; Ho, Y.-N.; Sun, C.-H.; Lee, H.-J.; Chen, P.-Y.; Shu, L.-J.; Wang, B.-W.; Hsu, W.-C.; Yang, Y.-L.

10.1101/2021.03.30.437786 — microbiology — Posted on 2021-03-31

93 Unipolar peptidoglycan synthesis in the Rhizobiales requires an essential class A penicillin-binding protein

Williams, M. A.; Aliashkevich, A.; Krol, E.; Kuru, E.; Bouchier, J. M.; Rittichier, J.; Brun, Y. V.; VanNieuwenhze, M. S.; Becker, A.; Cava, F.; Brown, P. J.

10.1101/2021.03.31.437934 — microbiology — Posted on 2021-03-31

94 An MHV macrodomain mutant predicted to lack ADP-ribose binding activity is severely attenuated, indicating multiple roles for the macrodomain in coronavirus replication

Voth, L. S.; O'Connor, J. J.; Kerr, C. M.; Doerger, E.; Schwarting, N.; Sperstad, P.; Johnson, D. K.; Fehr, A. R.

10.1101/2021.03.30.437796 — microbiology — Posted on 2021-03-31

95 Attention improves information flow between neuronal populations without changing the communication subspace

Srinath, R.; Ruff, D. A.; Cohen, M. R.

10.1101/2021.03.31.437940 — neuroscience — Posted on 2021-03-31

96 The effect of double biofeedback on functional hemispheric asymmetry and activity: a pilot study

Demareva, V.; Mukhina, E.; Bobro, T.

10.1101/2021.03.30.437721 — neuroscience — Posted on 2021-03-31

97 Fenbendazole resistance in Heterakis gallinarum, the vector of Histomonas meleagridis, the causative agent of Blackhead Disease in poultry.

Collins, J.; Jordan, B.; Bishop, A.; Kaplan, R. M.

10.1101/2021.03.30.437780 — zoology — Posted on 2021-03-31

98 Impact of fenbendazole resistance in Ascaridia dissimilis on the economics of production in turkeys

Collins, J.; Jordan, B.; Vidyashankar, A.; Jimenez Castro, P.; Kaplan, R. M.

10.1101/2021.03.30.437784 — zoology — Posted on 2021-03-31

99 Reducing publication delay to improve the efficiency and impact of conservation science

Christie, A. P.; White, T. B.; Martin, P. A.; Petrovan, S. O.; Bladon, A. J.; Bowkett, A. E.; Littlewood, N. A.; Mupepele, A.-C.; Rocha, R.; Sainsbury, K. A.; Smith, R. K.; Taylor, N. G.; Sutherland, W. J.

10.1101/2021.03.30.437223 — scientific communication and education — Posted on 2021-03-31

100 Furanoditerpenoid biosynthesis in the bioenergy crop switchgrass is catalyzed by an alternate metabolic pathway

Muchlinski, A. J.; Jia, M.; Tiedge, K. J.; Fell, J. S.; Pelot, K. A.; Chew, L.; Davisson, D. L.; Chen, Y.; Siegel, J.; Lovell, J. T.; Zerbe, P.

10.1101/2021.03.30.437764 — plant biology — Posted on 2021-03-31

101 ADAPTATION OF DOLPHINS (TURSIOPS TRUNCATUS) LOCATION SIGNALS WHEN SEARCHING AND RECOGNIZING OBJECTS HIDDEN BY SEA SEDIMENTS

Zaitseva, K.; Korolev, V.; Akhi, A.; Akhi, A.

10.1101/2021.03.30.437749 — physiology — Posted on 2021-03-31

102 Influence of substrate stiffness on barrier function in an iPSC-derived in vitro blood-brain barrier model

Bosworth, A.; Kim, H.; O'Grady, K.; Richter, I.; Lee, L.; O'Grady, B.; Lippmann, E.

10.1101/2021.03.31.437924 — bioengineering — Posted on 2021-03-31

103 Automatic Multi-functional Integration Program (AMFIP) towards All-optical Mechanobiology Interrogation

Luo, Q.; Zhang, J.; Lin, G.; Huang, M.; Tanaka, M.; Lepler, S.; Guan, J.; Siemann, D.; Tang, X.

10.1101/2021.03.31.437936 — bioengineering — Posted on 2021-03-31

104 Genome- and Transcriptome-wide Splicing Associations with Problematic Alcohol Use and Alcohol Use Disorder

Huggett, S. B.; Ikeda, A. S.; Yuan, Q.; Benca-Bachman, C. E.; Palmer, R. H. C.

10.1101/2021.03.31.437932 — genomics — Posted on 2021-03-31

105 Insight into Canary Island pine physiology provided by stable isotope patterns of water and plant tissues along an altitudinal gradient

Miranda, J. C.; Lehmann, M. M.; Saurer, M.; Altman, J.; Treydte, K.

10.1101/2021.03.30.437734 — ecology — Posted on 2021-03-31

106 Piecemeal regulation of convergent neuronal lineages by bHLH transcription factors in C. elegans

Masoudi, N.; Schnabel, R.; Hobert, O.

10.1101/2021.03.31.437939 — developmental biology — Posted on 2021-03-31

107 On the efficacy of restoration in stream networks: comments, critiques, and prospective recommendations

Murray-Stoker, D.

10.1101/611939 — ecology — Posted on 2021-03-31

108 Make Interactive Complex Heatmaps in R

Gu, Z.; Huebschmann, D.

10.1101/2021.03.08.434289 — bioinformatics — Posted on 2021-03-31

109 Deep learning from phylogenies to uncover the transmission dynamics of epidemics

Voznica, J.; Zhukova, A.; Boskova, V.; Saulnier, E.; Lemoine, F.; Moslonka-Lefebvre, M.; Gascuel, O.

10.1101/2021.03.11.435006 — bioinformatics — Posted on 2021-03-31

110 Contribution of enhancer-driven and master-regulator genes to autoimmune disease revealed using functionally informed SNP-to-gene linking strategies

Dey, K. K.; Gazal, S. K.; van de Geijn, B.; Kim, S. S.; Nasser, J.; Engreitz, J. M.; Price, A.

10.1101/2020.09.02.279059 — genetics — Posted on 2021-03-31

111 Spectrogram cross-correlation can be used to measure the complexity of bird vocalizations

Sawant, S.; Arvind, C.; Joshi, V.; Robin, V. V.

10.1101/2021.03.30.437665 — ecology — Posted on 2021-03-31

112 Stress fiber strain recognition by the LIM protein testin is cryptic and mediated by RhoA

Sala, S.; Oakes, P. W.

10.1101/2021.01.21.427693 — cell biology — Posted on 2021-03-31

113 Itaconate and its derivatives repress C2C12 myogenesis

Oh, T.; Hutchins, D.; Mainali, R.; Goslen, K.; Quinn, M. A.

10.1101/2021.02.01.429228 — cell biology — Posted on 2021-03-31

114 Cwl0971, a novel peptidoglycan hydrolase, plays pleiotropic roles in Clostridioides difficile R20291

Zhu, D.; Patabendige, H. M. L. W.; Tomlinson, B. R.; Wang, S.; Flores, D.; He, Y.; Shaw, L.; Sun, X.

10.1101/2020.11.29.402867 — microbiology — Posted on 2021-03-31

115 Arrayed multicycle drug screens identify broadly acting chemical inhibitors for repurposing against SARS CoV 2

Murer, L. P.; Volle, R.; Andriasyan, V.; Meili, N.; Yang, L.; Sequeira, D.; Gomez-Gonzalez, A.; Petkidis, A.; Olszewski, D.; Bauer, M.; Suomalainen, M.; Kuttler, F.; Turcatti, G.; Greber, U. F.

10.1101/2021.03.30.437771 — microbiology — Posted on 2021-03-31

116 Immunological factors, but not clinical features, predict visceral leishmaniasis relapse in patients co-infected with HIV

Takele, Y.; Mulaw, T.; Adem, E.; Shaw, C. J.; Franssen, S. U.; Womersley, R.; Kaforou, M.; Taylor, G. P.; Levin, M.; Muller, I.; Cotton, J. A.; Kropf, P.

10.1101/2021.03.30.437646 — immunology — Posted on 2021-03-31

117 A protective broadly cross-reactive human antibody defines a conserved site of vulnerability on beta-coronavirus spikes

Zhou, P.; Yuan, M.; Song, G.; Beutler, N.; Shaabani, N.; Huang, D.; He, W.-t.; Zhu, X.; Callaghan, S.; Yong, P.; Anzanello, F.; Peng, L.; Ricketts, J.; Parren, M.; Garcia, E.; Rawlings, S. A.; Smith, D. M.; Nemazee, D.; Teijaro, J. R.; Rogers, T.; Wilson, I. A.; Burton, D. R.; Andrabi, R.

10.1101/2021.03.30.437769 — immunology — Posted on 2021-03-31

118 Multi-compartment analysis of the complex gradient-echo signal quantifies myelin breakdown in premanifest Huntington's disease

Casella, C.; Kleban, E.; Rosser, A. E.; Coulthard, E.; Rickards, H.; Fasano, F.; Metzler-Baddeley, C.; Jones, D. K.

10.1101/2021.03.12.435119 — neuroscience — Posted on 2021-03-31

119 Caloric restriction overcomes pre-diabetic and hypertension induced by high fat diet and renal artery stenosis

Faria, M. S. d. S. N.; Pimentel, V. E.; Helaehil, J. V.; Bertolo, M. C.; Santos, N. T. H.; Silva-Neto, P. V. d.; Thomazini, B. F.; Oliveira, C. A. d.; Amaral, M. E. C. d.

10.1101/2021.03.30.437684 — physiology — Posted on 2021-03-31

120 Probing the killing potency of tumor-infiltrating lymphocytes on microarrayed autologous tumoroids

Dutta, D.; Rivest, F.; Lorenzo Martin, F.; Broguiere, N.; Tillard, L.; Ragusa, S.; Brandenberg, N.; Hoehnel, S.; Saugy, D.; Rusakiewicz, S.; Homicsko, K.; Coukos, G.; Lutolf, M. P.

10.1101/2021.03.30.437679 — cancer biology — Posted on 2021-03-31

121 Ovarian cancers with low CIP2A tumor expression constitute an APR-246 sensitive disease subtype

Cvrljevic, A. N.; Butt, U.; Huhtinen, K.; Gronroos, T.; Bockelman, C.; Lassus, H.; Kaipio, K.; Ristimaki, A.; Arsiola, T.; Laajala, T. D.; Connolly, D.; Carpen, O.; Pouwels, J.; Westermarck, J.

10.1101/2021.03.31.437804 — cancer biology — Posted on 2021-03-31

122 Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs

Hongu, T.; Pein, M.; Insua-Rodriguez, J.; Meier, J.; Decker, K.; Descot, A.; Riedel, A.; Oskarsson, T.

10.1101/2021.03.30.436797 — cancer biology — Posted on 2021-03-31

123 The long non-coding RNA MaTAR20 promotes mammary tumor growth by regulating angiogenesis pathways

Diermeier, S. D.; Chang, K.-C.; Frewen, A.; Benz, B. A.; Russo, S.; Nowak, D.; Hearn, S.; Yu, A.; Wilkinson, J. E.; Rigo, F.; Spector, D.

10.1101/2021.03.30.437774 — cancer biology — Posted on 2021-03-31

124 Drift correction in localization microscopy using entropy minimization

Cnossen, J.; Cui, T. J.; Joo, C.; Smith, C. S.

10.1101/2021.03.30.437682 — biophysics — Posted on 2021-03-31

125 Structural insights into the activation of human calcium-sensing receptor

Chen, X.; Wang, L.; Ding, Z.; Cui, Q.; Han, L.; Kou, Y.; Zhang, W.; Wang, H.; Jia, X.; Dai, M.; Shi, Z.; Li, Y.; Li, X.; Geng, Y.

10.1101/2021.03.30.437720 — biophysics — Posted on 2021-03-31

126 Biophysical properties of a tau seed

Hou, Z.; Chen, D.; Ryder, B. D.; Joachimiak, L. A.

10.1101/2021.03.30.437772 — biophysics — Posted on 2021-03-31

127 Restriction of RecG translocation by DNA mispairing

Sun, Z.; Wang, Y.; Hashemi, M.; Bianco, P.; Lyubchenko, Y. L.

10.1101/2021.03.31.437879 — biophysics — Posted on 2021-03-31

128 ATP allosterically stabilizes Integrin-linked kinase for efficient force generation

Martin, I. M.; Nava, M. M.; Wickstroem, S. A.; Graeter, F.

10.1101/2021.03.30.437490 — biophysics — Posted on 2021-03-31

129 Multiple timescales in bacterial growth homeostasis

Stawsky, A.; Vashistha, H.; Salman, H.; Brenner, N.

10.1101/2021.03.30.437502 — biophysics — Posted on 2021-03-31

130 Fluid mechanics of mosaic ciliated tissues

Boselli, F.; Jullien, J.; Lauga, E.; Goldstein, R. E.

10.1101/2021.03.31.437829 — biophysics — Posted on 2021-03-31

131 Exploring the role of glycans in the interaction of SARS-CoV-2 RBD and human receptor ACE2

Nguyen, K.; Chakraborty, S.; Mansbach, R.; Korber, B.; Gnanakaran, S.

10.1101/2021.03.30.437783 — biophysics — Posted on 2021-03-31

132 rTASSEL: an R interface to TASSEL for association mapping of complex traits

Monier, B.; Casstevens, T. M.; Bradbury, P. J.; Buckler, E. S.

10.1101/2020.07.21.209114 — bioinformatics — Posted on 2021-03-31

133 LanceOtron: a deep learning peak caller for ATAC-seq, ChIP-seq, and DNase-seq

Hentges, L. D.; Sergeant, M. D.; Downes, D. J.; Hughes, J. R.; Taylor, S.

10.1101/2021.01.25.428108 — bioinformatics — Posted on 2021-03-31

134 CIAlign - A highly customisable command line tool to clean, interpret and visualise multiple sequence alignments.

Tumescheit, C.; Firth, A. E.; Brown, K.

10.1101/2020.09.14.291484 — bioinformatics — Posted on 2021-03-31

135 Supramolecular cylinders target bulge structures in the 5-prime UTR of the RNA genome of SARS-CoV-2 and inhibit viral replication

Melidis, L.; Hill, H. J.; Coltman, N. J.; Davies, S. P.; Winczura, K.; Chauhan, T.; Craig, J. S.; Garai, A.; Hooper, C. A. J.; Egan, R. T.; McKeating, J. A.; Hodges, N. J.; Stamataki, Z.; Grzechnik, P.; Hannon, M. J.

10.1101/2021.03.30.437757 — biochemistry — Posted on 2021-03-31

136 BRED: bioluminescence energy transfer to dye for monitoring ceramide trafficking in cell

Naseri, G.; Arenz, C.

10.1101/2021.03.31.437878 — biochemistry — Posted on 2021-03-31

137 Facilitating population genomics of non-model organisms through optimized experimental design for reduced representation sequencing

Christiansen, H.; Heindler, F. M.; Hellemans, B.; Jossart, Q.; Pasotti, F.; Robert, H.; Verheye, M.; Danis, B.; Kochzius, M.; Leliaert, F.; Moreau, C.; Patel, T.; Van de Putte, A. P.; Vanreusel, A.; Volckaert, F. A. M.; Schoen, I.

10.1101/2021.03.30.437642 — genomics — Posted on 2021-03-31

138 The plastid genome characteristics of a moth orchid (Phalaenopsis wilsoniii, Orchidaceae)

Xia, K.; Liu, D.-K.; Wang, J.-Y.

10.1101/2021.03.30.437522 — genomics — Posted on 2021-03-31

139 Ultra-deep whole genome bisulfite sequencing reveals a single methylation hotspot in human brain mitochondrial DNA

Guitton, R.; Dölle, C.; Alves, G.; Tysnes, O. B.; Nido, G. S.; Tzoulis, C.

10.1101/2021.03.30.437685 — genomics — Posted on 2021-03-31

140 Evolution of the insect PPK gene family

Latorre Estivalis, J. M.; Cunha Almeida, F.; Pontes, G.; Dopazo, H.; Barrozo, R.; Lorenzo, M. G.

10.1101/2021.03.30.437681 — genomics — Posted on 2021-03-31

141 The protective effect of sickle cell haemoglobin against severe malaria depends on parasite genotype

Band, G.; Leffler, E. M.; Jallow, M.; Sisay-Joof, F.; Ndila, C. M.; Macharia, A. W.; Hubbart, C.; Jeffreys, A. E.; Rowlands, K.; Nguyen, T.; Goncalves, S. M.; Ariani, C. V.; Stalker, J.; Pearson, R. D.; Amato, R.; Drury, E.; Sirugo, G.; d'Alessandro, U.; Bojang, K. A.; Marsh, K.; Peshu, N. N. P.; Conway, D. J.; Williams, T. N.; Rockett, K. A.; Kwiatkowski, D. P.

10.1101/2021.03.30.437659 — genetics — Posted on 2021-03-31

142 Dissolved organic matter from tropical peatlands impacts shelf sea light availability on coral reefs in the Singapore Strait, Southeast Asia

Martin, P.; Sanwlani, N.; Lee, T. W. Q.; Wong, J. M. C.; Chang, K.; Wong, E. W.-S.; Liew, S. C.

10.1101/2021.03.30.437655 — ecology — Posted on 2021-03-31

143 Spatially Explicit Modeling of Community Occupancy using Markov Random Field Models with Imperfect Observation: Mesocarnivores in Apostle Islands National Lakeshore

Shen, Y.; Olson, E.; Van Deelen, T. R.

10.1101/2020.08.05.238774 — ecology — Posted on 2021-03-31

144 Nuclear export of the pre-60S ribosomal subunit through single nuclear pores observed in real time

Ruland, J. A.; Krueger, A. M.; Doerner, K. E.; Bhatia, R.; Wirths, S.; Poetes, D.; Kutay, U.; Siebrasse, J. P.; Kubitscheck, U.

10.1101/2021.03.30.437662 — cell biology — Posted on 2021-03-31

145 Differential effects of environmental and endogenous 24h rhythms within a deep-coverage spatiotemporal proteome

Kay, H. M.; Grunewald, E.; Feord, H. K.; Gil, S.; Peak-Chew, S. Y.; Stangherlin, A.; O'Neill, J. S.; van Ooijen, G.

10.1101/2021.03.30.437663 — cell biology — Posted on 2021-03-31

146 High-resolution 3D reconstruction of human oocytes using FIB-SEM.

Trebichalska, Z.; Javurek, J.; Tatickova, M.; Kyjovska, D.; Kloudova, S.; Otevrel, P.; Hampl, A.; Holubcova, Z.

10.1101/2021.03.30.437653 — cell biology — Posted on 2021-03-31

147 Eosinophils restrict diesel exhaust particles induced cell proliferation of lung epithelial A549 cells, vial interleukin-13 mediated mechanisms: implications for tissue remodelling and fibrosis

Niranjan, R.; Subramanian, M.; Panneer, D.; Ojha, S. K.

10.1101/2021.03.30.436369 — cell biology — Posted on 2021-03-31

148 Kinetochore life histories reveal the origins of chromosome mis-segregation and correction mechanisms

Sen, O.; Harrison, J. U.; Burroughs, N. J.; McAinsh, A. D.

10.1101/2021.03.30.436326 — cell biology — Posted on 2021-03-31

149 A DNA repair-independent role for alkyladenine DNA glycosylase in alkylation-induced unfolded protein response

Milano, L.; Charlier, C. F.; Andreguetti, R.; Cox, T.; Healing, E.; Thome, M. P.; Elliott, R. M.; Samson, L. D.; Masson, J.-Y.; Lenz, G.; Henriques, J. A. P.; Nohturfft, A.; Meira, L. B.

10.1101/2021.03.31.437844 — cell biology — Posted on 2021-03-31

150 Cellular variability of nonsense-mediated mRNA decay

Sato, H.; Singer, R. H.

10.1101/2021.03.31.437867 — cell biology — Posted on 2021-03-31

151 Revisiting the role of Toxoplasma gondii ERK7 in the maintenance and stability of the apical complex

Soldati-Favre, D.; Dos Santos Pacheco, N.; Tosetti, N.; Krishnan, A.; Haase, R.

10.1101/2021.03.22.436543 — microbiology — Posted on 2021-03-31

152 Perceptual and Semantic Representations at Encoding Contribute to True and False Recognition of Objects

Naspi, L.; Hoffman, P.; Devereux, B.; Morcom, A.

10.1101/2021.03.31.437847 — neuroscience — Posted on 2021-03-31

153 NeuriteNet: A Convolutional Neural Network for determining morphological differences in neurite growth

Vecchi, J. T.; Mullan, S.; Lopez, J. A.; Hansen, M.; Sonka, M.; Lee, A.

10.1101/2021.03.31.437885 — neuroscience — Posted on 2021-03-31

154 An ammonium transporter is a non-canonical olfactory receptor for ammonia

Vulpe, A.; Kim, H. S.; Ballou, S.; Wu, S.-T.; Grabe, V.; Nava Gonzales, C.; Sachse, S.; Jeanne, J. M.; Su, C.-Y.; Menuz, K.

10.1101/2021.03.31.437861 — neuroscience — Posted on 2021-03-31

155 Locus coeruleus activity improves cochlear implant performance

Glennon, E.; Zhu, A.; Wadghiri, Y. Z.; Svirsky, M. A.; Froemke, R. C.

10.1101/2021.03.31.437870 — neuroscience — Posted on 2021-03-31

156 Estimating smooth and sparse neural receptive fields with a flexible spline basis

Huang, Z.; Ran, Y.; Euler, T.; Berens, P.

10.1101/2021.03.31.437831 — neuroscience — Posted on 2021-03-31

157 Scn1a-GFP transgenic mouse revealed Nav1.1 expression in neocortical pyramidal tract projection neurons

Yamagata, T.; Ogiwara, I.; Tatsukawa, T.; Otsuka, Y.; Mazaki, E.; Inoue, I.; Tokonami, N.; Hibi, Y.; Itohara, S.; Yamakawa, K.

10.1101/2021.03.31.437794 — neuroscience — Posted on 2021-03-31

158 Interpreting Null Models of Resting-State Functional MRI

Liegeois, R.; Yeo, T. B. T.; Van De Ville, D.

10.1101/2021.03.30.437514 — neuroscience — Posted on 2021-03-31

159 Erasing motion: Scrambling direction selectivity in visual cortex during saccades

Miura, S. K.; Scanziani, M.

10.1101/2021.03.30.437338 — neuroscience — Posted on 2021-03-31

160 Aging is associated with a degeneration of noradrenergic-, but not dopaminergic-neurons, in the short-lived killifish Nothobranchius furzeri.

Bagnoli, S.; Fronte, B.; Bibbiani, C.; Terzibasi Tozzini, E.; Cellerino, A.

10.1101/2021.03.31.437850 — neuroscience — Posted on 2021-03-31

161 Depleting Hypothalamic Somatostatinergic Neurons Recapitulates Diabetic Phenotypes in Brain, Bone Marrow, Adipose, and Retina

Huang, C.; Rosencrans, R. F.; Bugescu, R.; Vieira, C. P.; Hu, P.; Adu-Agyeiwaah, Y.; Gamble, K.; Longhini, A. L. F.; Fuller, P. M.; Leinninger, G. M.; Grant, M.

10.1101/2021.03.30.437706 — neuroscience — Posted on 2021-03-31

162 Schizophrenia Risk Proteins ZNF804A and NT5C2 Interact at Synapses

Aabdien, A.; Sichlinger, L.; Gatford, N. J. F.; Raval, P.; Jones, M. R.; Tanangonan, L.; Powell, T. R.; Duarte, R. R. R.; Srivastava, D. P.

10.1101/2021.03.31.437821 — neuroscience — Posted on 2021-03-31

163 Modulation of taste sensitivity by the olfactory system in Drosophila

Junca, P.; Stanley, M.; Musso, P.-Y.; Gordon, M. D.

10.1101/2021.03.30.437740 — neuroscience — Posted on 2021-03-31

164 Sleep Slow Oscillations and Spindles encode ocular dominance plasticity and promote its consolidation in adult humans

Menicucci, D.; Lunghi, C.; Zaccaro, A.; Morrone, M. C.; Gemignani, A.

10.1101/2021.03.31.437408 — neuroscience — Posted on 2021-03-31

165 Organ-specific microbiota enhances the terrestrial lifestyle of a brachyuran crab

Bacci, G.; Fratini, S.; Meriggi, N.; Cheng, C. L. Y.; Ng, K. H.; Iannucci, A.; Mengoni, A.; Cavalieri, D.; Cannicci, S.

10.1101/2021.03.30.437674 — zoology — Posted on 2021-03-31

166 Production of Volatile Moth Sex Pheromones in Transgenic Nicotiana benthamiana Plants

Mateos-Fernandez, R.; Moreno Gimenez, E.; Gianoglio, S.; Quijano-Rubio, A.; Gavalda-Garcia, J.; Estelles, L.; Rubert, A.; Rambla, J. L.; Vazquez-Vilar, M.; Huet, E.; Fernandez-del-Carmen, A.; Espinosa-Ruiz, A.; Jutersek, M.; Vacas, S.; Navarro, I.; Navarro-Llopis, V.; Orzaez, D.

10.1101/2021.03.31.437903 — synthetic biology — Posted on 2021-03-31

167 A morpho-transcriptomic map of brassinosteroid action in the Arabidopsis root

Graeff, M.; Rana, S.; Wendrich, J. R.; Dorier, J.; Eekhout, T.; Aliaga Fandino, A. C.; Guex, N.; Bassel, G. W.; De Rybel, B.; Hardtke, C. S.

10.1101/2021.03.30.437656 — plant biology — Posted on 2021-03-31

168 Acclimation of Chlamydomonas reinhardtii to Nitric Oxide Stress Related to Respiratory Burst Oxidase-Like 2

Lee, T.-M.; Kuo, E. Y.

10.1101/2021.03.30.437739 — plant biology — Posted on 2021-03-31

169 Plant Metabolic Network: A multi-species resource of plant metabolic information

Hawkins, C. L.; Ginzburg, D.; Zhao, K.; Dwyer, W.; Xue, B.; Xu, A.; Rice, S. L.; Cole, B.; Paley, S. M.; Karp, P.; Rhee, S. Y.

10.1101/2021.03.30.437738 — plant biology — Posted on 2021-03-31

170 Auxin-responsive (phospho)proteome analysis reveals regulation of cell cycle and ethylene signaling during rice crown root development

Singh, H.; Singh, Z.; Zhu, T.; Xu, X.; Waghmode, B.; Garg, T.; Yadav, S.; Sircar, D.; De Smet, I.; Yadav, S. R.

10.1101/2021.03.30.437660 — plant biology — Posted on 2021-03-31

171 Biomolecular solid-state NMR spectroscopy at highest field: the gain in resolution at 1200 MHz

Calon, M.; Malar, A. A.; Pfister, S.; Rimal, V.; Weber, M. E.; Wiegand, T.; Zehnder, J.; Chavez, M.; Deb, R.; Cadalbert, R.; Dapp, A.; Fogeron, M.-L.; Hunkeler, A.; Lecoq, L.; Torosyan, A.; Zyla, D.; Glockshuber, R.; Jonas, S.; Nassal, M.; Ernst, M.; Bockmann, A.; Meier, B. H.

10.1101/2021.03.31.437892 — biophysics — Posted on 2021-03-31

172 Comparison of Type-1 and Type-2 Fuzzy Systems forMineralization of Bioprinted Bone

Sedigh, A.; Akbarzadeh-T, M.-R.; Tomlinson, R. E.

10.1101/2021.03.31.437908 — bioinformatics — Posted on 2021-03-31

173 Memory specific to temporal features of sound is formed by cue-selective enhancements in temporal coding enabled by inhibition of an epigenetic regulator

Rotondo, E. K.; Bieszczad, K. M.

10.1101/2021.03.31.437889 — animal behavior and cognition — Posted on 2021-03-31

174 DiaThor: R package for computing diatom metrics and biotic indices

Nicolosi Gelis, M. M.; Sathicq, M. B.; Jupke, J.; Cochero, J.

10.1101/2021.03.31.437895 — ecology — Posted on 2021-03-31

175 Are narrow-ranging species doomed to extinction? Dramatic and generalised decline in future climate suitability of highly threatened species

Dubos, N.; Montfort, F.; Grinand, C.; Nourtier, M.; Deso, G.; Probst, J.-M.; Razafimanahaka, J. H.; Andriantsimanarilafy, R. R.; Rakotondrasoa, E. F.; Razafindraibe, P.; Jenkins, R.; Crottini, A.

10.1101/2021.03.30.437650 — ecology — Posted on 2021-03-31

176 Building reusable phage and antibiotic treatments via exploitation of bacteria-phage coevolutionary dynamics.

Gurney, J.; Brown, S. P.

10.1101/2021.03.31.437900 — microbiology — Posted on 2021-03-31

177 Neocortical rhythm entrainment by parvalbumin-positive interneurons across cortical layers

David, F.; Borel, M.; Ayub, S.; Ruther, P.; Gentet, L.

10.1101/2021.03.31.437894 — neuroscience — Posted on 2021-03-31

178 Modeling High-grade serous ovarian carcinoma using a combination of in vivo electroporation and CRISPR/Cas9 mediated genome editing

Teng, K.; Ford, M. J.; Harwalkar, K.; Li, Y.; Farnell, D.; Yamanaka, N.; Tuyet Nhung, T. N.; Huntsman, D. G.; Arseneau, J.; Yamanaka, Y.

10.1101/2021.03.29.437221 — cancer biology — Posted on 2021-03-31

179 ALOHA: Aggregated local extrema splines for high-throughput dose-response analysis

Davidson, S. E.; Wheeler, M. W.; Auerbach, S. S.; Sivaganesan, S.; Medvedovic, M.

10.1101/2021.03.29.437588 — bioinformatics — Posted on 2021-03-31

180 scAMACE: Model-based approach to the joint analysis of single-cell data on chromatin accessibility, gene expression and methylation

Wangwu, J.; Sun, Z.; Lin, Z.

10.1101/2021.03.29.437485 — bioinformatics — Posted on 2021-03-31

181 Genomic analysis of patient-derived xenograft models reveals intra-tumor heterogeneity in endometrial cancer and can predict tumor growth inhibition with talazoparib

Bonazzi, V. F.; Kondrashova, O.; Smith, D.; Nones, K.; Sengal, A. T.; Ju, R.; Packer, L. M.; Koufariotis, L. T.; Kazakoff, S. H.; Davidson, A. L.; Ramarao-Milne, P.; Lakis, V.; Newell, F.; Rogers, R.; Davies, C.; Nicklin, J.; Garrett, A.; Chetty, N.; Perrin, L.; Pearson, J. V.; Patch, A.-M.; Waddell, N.; Pollock, P.

10.1101/2021.03.30.436914 — genomics — Posted on 2021-03-31

182 H3K9 methyltransferase EHMT2/G9a controls ERVK-driven non-canonical imprinted genes

Zeng, T.-B.; Pierce, N.; Szabo, P.

10.1101/2021.03.29.437617 — genetics — Posted on 2021-03-31

183 Dynamics of data availability in disease modeling: An example evaluating the trade-offs of ultra-fine-scale factors applied to human West Nile virus disease models in the Chicago area, USA

Uelmen, J. A.

10.1101/2021.03.29.437618 — ecology — Posted on 2021-03-31

184 Extensive aquatic subsidies lead to territorial breakdown and high density of an apex predator

Eriksson, C. E.; Kantek, D. L. Z.; Miyazaki, S. S.; Morato, R. G.; dos Santos-Filho, M.; Ruprecht, J. S.; Peres, C. A.; Levi, T.

10.1101/2021.03.29.437596 — ecology — Posted on 2021-03-31

185 Influence of short-term temperature drops on sex-determination in sea turtles

Porter, E.; Booth, D. T.; Limpus, C. J.

10.1101/2021.03.29.437634 — ecology — Posted on 2021-03-31

186 Taxonomic scale dependency of Bergmann's patterns: A cross-scale comparison of hawkmoths and birds along a tropical elevational gradient

Mungee, M.; Athreya, R.; Pandit, R.

10.1101/2021.03.29.437440 — ecology — Posted on 2021-03-31

187 TGIF1 is required for chicken ovarian cortical development and generation of the juxtacortical medulla

Estermann, M. A.; Hirst, C. E.; Major, A. T.; Smith, C. A.

10.1101/2021.03.30.437645 — developmental biology — Posted on 2021-03-31

188 Caspases switch off m6A RNA modification pathway to reactivate a ubiquitous human tumor virus

Zhang, K.; Zhang, Y.; Wan, J.; Maharjan, Y.; Sugiokto, F. G.; Li, R.

10.1101/2020.11.12.377127 — microbiology — Posted on 2021-03-31

189 Robust phylogenetic position of the enigmatic hydrozoan, Margelopsis haeckelii revealed within the family Corymorphidae

Kupaeva, D. M.; Lebedeva, T. S.; Ashurkova, T. P.; Prudkovsky, A. A.; Vanwalleghem, D.; Kremnyov, S. V.

10.1101/2021.03.30.437375 — zoology — Posted on 2021-03-31

190 The truncate soft-shell clam, Mya truncata, as a biomonitor of municipal wastewater exposure and historical anthropogenic impacts in the Canadian Arctic.

Schaefer, C. M.; Deslauriers, D.; Jeffries, K. M.

10.1101/2021.03.29.437602 — pharmacology and toxicology — Posted on 2021-03-31

191 Human DICER helicase domain recruits PKR and modulates its antiviral activity

Montavon, T. C.; Baldaccini, M.; Lefevre, M.; Girardi, E.; Chane-Woon-Ming, B.; Messmer, M.; Hammann, P.; Chicher, J.; Pfeffer, S.

10.1101/2020.05.14.095356 — microbiology — Posted on 2021-03-31

192 The diagonal band of broca regulates olfactory-mediated behaviors by modulating odor-evoked responses within the olfactory bulb

Schwarz, I.; Mueller, M.; Pavlova, I.; Schweihoff, J. F.; Musacchio, F.; Mittag, M.; Fuhrmann, M.; Schwarz, M. K.

10.1101/2020.11.07.372649 — neuroscience — Posted on 2021-03-31

193 An altered balance of integrated and segregated brain activity is a marker of cognitive deficits following sleep deprivation

Cross, N.; Pomares, F. B.; Nguyen, A.; Perrault, A. A.; Jegou, A.; Uji, M.; Lee, K.; Razavipour, F.; Ali, O. B. K.; Aydin, U.; Benali, H.; Grova, C.; Dang-Vu, T. T.

10.1101/2020.11.28.402305 — neuroscience — Posted on 2021-03-31

194 SingleChannelNet: A Model for Automatic Sleep Stage Classification with Raw Single-Channel EEG

Zhou, D.; Hu, G.; Zhang, J.; Wang, J.; Yan, R.; Li, F.; Xu, Q.; Kettunen, L.; Chang, Z.; Cong, F.

10.1101/2020.09.21.306597 — bioengineering — Posted on 2021-03-31

195 Micrococcal nuclease sequencing of porcine sperm suggests a nucleosomal involvement on semen quality and early embryo development

Godia, M.; Hammoud, S. S.; Naval-Sanchez, M.; Ponte, I.; Rodriguez-Gil, J. E.; Sanchez, A.; Clop, A.

10.1101/2021.03.30.437505 — genomics — Posted on 2021-03-31

196 Dopamine facilitates fear memory formation in the human amygdala

Frick, A.; Bjorkstrand, J.; Lubberink, M.; Eriksson, A.; Fredrikson, M.; Ahs, F.

10.1101/2021.03.31.437765 — neuroscience — Posted on 2021-03-31

197 Profiling Germline Adaptive Immune Receptor Repertoire with gAIRR Suite

Lin, M.-J.; Lin, Y.-C.; Chen, N.-C.; Luo, A. C.; Lai, S.-K.; Hsu, C.-L.; Hsu, J. S.; Chen, C.-Y.; Yang, W.-S.; Chen, P.-L.

10.1101/2020.11.27.399857 — genomics — Posted on 2021-03-31

198 Evolutionary mechanisms that determine which bacterial genes are carried on plasmids

Lehtinen, S.; Huisman, J. S.; Bonhoeffer, S.

10.1101/2020.08.04.236455 — evolutionary biology — Posted on 2021-03-31

199 Contact-tracing in cultural evolution: a Bayesian mixture model to detect geographic areas of language contact

Ranacher, P.; Neureiter, N.; van Gijn, R.; Sonnenhauser, B.; Escher, A.; Weibel, R.; Muysken, P.; Bickel, B.

10.1101/2021.03.31.437731 — evolutionary biology — Posted on 2021-03-31

200 Decoding the molecular landscape of the developing spatial processing system and production of entorhinal stellate cell-like cells by a direct programming approach.

Liu, Y.; Bergmann, T.; Mogus, L.; Lee, J.; Pfisterer, U.; Handfield, L.-F.; Asenjo-Martinez, A.; Lisa-Vargas, I.; Seemann, S. E.; Hang Lee, J. T.; Patikas, N.; Rahbek Kornum, B.; Denham, M.; Hyttel, P.; Witter, M. P.; Gorodkin, J.; Pers, T.; Hemberg, M.; Khodosevich, K.; Hall, V. J.

10.1101/738443 — developmental biology — Posted on 2021-03-31

201 Expression of Sonic Hedgehog and Pathway Components in the Embryonic Mouse Head: Anatomical Relationships Between Regulators of Positive and Negative Feedback

Sigulinsky, C. L.; Li, X.; Levine, E. M.

10.1101/2021.03.30.437697 — developmental biology — Posted on 2021-03-31

202 Arf GTPase-Activating proteins SMAP1 and AGFG2 regulate the size of Weibel-Palade bodies and exocytosis of von Willebrand factor

Watanabe, A.; Hataida, H.; Inoue, N.; Kamon, K.; Baba, K.; Sasaki, K.; Kimura, R.; Sasaki, H.; Eura, Y.; Ni, W.-F.; Shibasaki, Y.; Waguri, S.; Kokame, K.; shiba, y.

10.1101/2021.03.29.437631 — cell biology — Posted on 2021-03-31

203 Extracellular vesicles synchronize cellular phenotypes of differentiating cells

Minakawa, T.; Matoba, T.; Yamashita, J. K.

10.1101/2021.03.30.437638 — cell biology — Posted on 2021-03-31

204 Genome sequencing and functional genes comparison between Sphingopyxis USTB-05 and Sphingomonas morindae NBD5

Liu, C.; Xu, Q.; Zhao, Z.; Ahmad, S.; Zhang, H.; Zhang, Y.; Pang, Y.; Aikemu, A.; Liu, Y.; Yan, H.

10.1101/2021.03.29.437629 — microbiology — Posted on 2021-03-31

205 Diverse viruses carrying genes for microbial extremotolerance in the Atacama Desert hyperarid soil

Hwang, Y.; Rahlff, J.; Schulze-Makuch, D.; Schloter, M.; Probst, A. J.

10.1101/2020.09.21.307520 — microbiology — Posted on 2021-03-31

206 Population Codes Enable Learning from Few Examples By Shaping Inductive Bias

Bordelon, B.; Pehlevan, C.

10.1101/2021.03.30.437743 — neuroscience — Posted on 2021-03-31

207 Assessment of Neurovascular Coupling & Cortical Spreading Depression in Mixed Models of Atherosclerosis & Alzheimer's Disease

Shabir, O.; Pendry, B.; Lee, L. M.; Eyre, B.; Sharp, P.; Rebollar, M. A.; Howarth, C.; Heath, P. R.; Wharton, S. B.; Francis, S.; Berwick, J.

10.1101/2020.08.13.249987 — neuroscience — Posted on 2021-03-31

208 Distinct motivations to seek out information in healthy and addicted 1 individuals

Cogliati Dezza, I.; Noel, X.; Cleeremans, A.; Yu, A.

10.1101/2020.02.19.955989 — neuroscience — Posted on 2021-03-31

209 Calcium-independent astrocytic lipid release modulates neuronal excitability

Wang, F.; Bradshaw, H. B.; Jablonska, B.; Pena, S. E.; Xavier, J.; Gong, S.; Li, B.; Chandler-Militello, D.; Bekar, L. K.; Smith, N. A.

10.1101/2020.01.12.903393 — neuroscience — Posted on 2021-03-31

210 Organelle calcium-derived voltage oscillations in pacemaker neurons drive food-seeking behavior in Aplysia

Bedecarrats, A.; Puygrenier, L.; Castro O'Byrne, J.; Lade, Q.; Simmers, J.; Nargeot, R.

10.1101/2021.03.30.437701 — neuroscience — Posted on 2021-03-31

211 Fine-tuning of SUMOylation modulates drought tolerance

Guan, Q.; Li, X.; Zhou, S.-X.; Lu, L.; Dang, H.; Liu, Z.; Li, H.; Chu, B.; Chen, P.; Ma, Z.; Zhao, S.; Van Nocker, S.; Ma, F.

10.1101/2021.03.29.437542 — plant biology — Posted on 2021-03-31

212 Chromosomal rearrangements but no change of genes and transposable elements repertoires in an invasive forest-pathogenic fungus

Demene, A.; Laurent, B.; Cros-Arteil, S.; Boury, C.; Dutech, C.

10.1101/2021.03.09.434572 — genomics — Posted on 2021-03-31

213 Effect of a Monascus sp. red yeast rice extract on germination of bacterial spores

Husakova, M.; Plechata, M.; Branska, B.; Patakova, P.

10.1101/2021.03.26.437149 — microbiology — Posted on 2021-03-31

214 Sinorhizobium meliloti functions required for resistance to antimicrobial NCR peptides and bacteroid differentiation

Nicoud, Q.; Barriere, Q.; Busset, N.; Dendene, S.; Travin, D. Y.; Bourge, M.; Le Bars, R.; Boulogne, C.; Lecroël, M.; Jenei, S.; Kereszt, A.; Kondorosi, E.; Biondi, E. G.; Timtchenko, T.; Alunni, B.; Mergaert, P.

10.1101/2020.12.04.412775 — microbiology — Posted on 2021-03-31

215 Integrating reward information for prospective behaviour

Hall-McMaster, S.; Stokes, M. G.; Myers, N. E.

10.1101/2021.03.30.437719 — neuroscience — Posted on 2021-03-31

216 SpheroidPicker: An Automated 3D cell culture manipulator robot using deep learning

Grexa, I.; Diosdi, A.; Kriston, A.; Moshkov, N.; Harmati, M.; Buzas, K.; Pietiainen, V.; Koos, K.; Hovath, P.

10.1101/2020.11.25.397331 — bioengineering — Posted on 2021-03-31

217 Additive and synergistic effects of arbuscular mycorrhizal fungi, insect pollination and nutrient availability in a perennial fruit crop

Chen, K.; Kleijn, D.; Scheper, J.; Fijen, T. P. M.

10.1101/2021.03.11.434774 — ecology — Posted on 2021-03-30

218 Chromatin accessibility determines cell-type specific intron retention

Petrova, V.; Song, R.; DEEP Consortium, ; Nordstrom, K. J. V.; Walter, J.; Wong, J. J.- L.; Armstrong, N. J.; Rasko, J. J. E.; Schmitz, U.

10.1101/2021.02.17.431609 — bioinformatics — Posted on 2021-03-30

219 Proteomics reveals commitment to germination in barley seeds is marked by loss of stress response proteins and mobilisation of nutrient reservoirs

Osama, S. K.; Kerr, E. D.; Yousif, A. M.; Phung, T. K.; Kelly, A. M.; Fox, G. P.; Schulz, B. L.

10.1101/2020.06.02.130823 — biochemistry — Posted on 2021-03-30

220 Taming Strong Selection with Large Sample Sizes

Gravel, S.; Krukov, I.

10.1101/2021.03.30.437711 — genetics — Posted on 2021-03-30

221 Unaffected functional recovery after spinal cord contusions at different circadian times

Slomnicki, L.; Wei, G.; Burke, D.; Whittemore, S.; Saraswat Ohri, S.; Hetman, M.

10.1101/2021.03.30.437713 — neuroscience — Posted on 2021-03-30

222 Novel insights in the pathophysiology of α-synuclein dysregulation on D2 receptor activity contributing to the vulnerability of dopamine neurons

Dagra, A.; Miller, D. R.; Shaerzadeh, F.; Lin, M.; Gopinath, A.; Harris, S.; Sorrentino, Z. A.; Velasco, S.; Alonge, A. R.; Azar, J.; Lebowitz, J. J.; Ulm, B.; Bu, A.-M.; Hansen, C. A.; Urs, N. M.; Giasson, B. I.; Khoshbouei, H.

10.1101/2021.03.30.437775 — neuroscience — Posted on 2021-03-30

223 PharmOmics: A Species- and Tissue-specific Drug Signature Database and Online Tool for Drug Repurposing

CHEN, Y.-W.; Diamante, G.; Ding, J.; Nghiem, T. X.; Ha, S.-m.; Cohn, P.; Arneson, D.; Blencowe, M.; Garcia, J.; Zaghari, N.; Patel, P.; Yang, J.; Yang, X.

10.1101/837773 — systems biology — Posted on 2021-03-30

224 Epigenome erosion drives neural crest-like phenotypic mimicry in triple-negative breast cancer and other SOX10+ malignancies

Saunus, J. M.; De Luca, X. M.; Northwood, K.; Raghavendra, A.; Hasson, A.; McCart Reed, A. E.; Lim, M.; Lal, S.; Vargas, A. C.; Kutasovic, J. R.; Dalley, A. J.; Miranda, M.; Kalaw, E.; Kalita-de Croft, P.; Gresshoff, I.; Al-Ejeh, F.; Gee, J. M.; Ormandy, C. J.; Khanna, K. K.; Beesley, J.; Chenevix-Trench, G.; Green, A. R.; Rakha, E. A.; Ellis, I. O.; Nicolau, D. V.; Simpson, P. T.; Lakhani, S. R.

10.1101/2021.03.30.437624 — cancer biology — Posted on 2021-03-30

225 The nuclear receptor DHR3/Hr46 is required in the blood brain barrier of mature males for courtship

Lama, C.; Love, C. R.; Le, H. N.; Lama, J.; Dauwalder, B.

10.1101/2021.03.30.437714 — animal behavior and cognition — Posted on 2021-03-30

226 Deficiency of SYCP3-related XLR3 Disrupts the Initiation of Meiotic Sex Chromosome Inactivation in Mouse Spermatogenesis

O'Neill, M. J.; Sobel Naveh, N.; Foley, R.; DeNegre, K.; Evans, T.; Czechanski, A.; Reinholdt, L.

10.1101/2021.03.30.437712 — genetics — Posted on 2021-03-30

227 Osteoblast-Specific Wnt Secretion is Required for Skeletal Homeostasis and Loading-Induced Bone Formation in Adult Mice

Lawson, L. Y.; Brodt, M. D.; Migotsky, N.; Chermside-Scabbo, C.; Palaniappan, R.; Silva, M. J.

10.1101/2021.03.30.437737 — genetics — Posted on 2021-03-30

228 Epigenetic clock and methylation studies in dogs

Horvath, S.; Lu, A. T.; Haghani, A.; Zoller, J. A.; Brooke, R. T.; Raj, K.; Plassais, J.; Hogan, A. N.; Ostrander, E. A.

10.1101/2021.03.30.437604 — developmental biology — Posted on 2021-03-30

229 Spermiogenesis alterations in the absence of CTCF revealed by single cell RNA sequencing

Torres-Flores, U.; Diaz-Espinosa, F.; Lopez-Santaella, T.; Rebollar-Vega, R.; Vazquez-Jimenez, A.; Taylor, I. J.; Ortiz-Hernandez, R.; Echeverria, O. M.; Vazquez-Nin, G. H.; Gutierrez-Ruiz, M. C.; De la Rosa-Velazquez, I. A.; RESENDIS-ANTONIO, O.; Hernandez-Hernandez, A.

10.1101/2021.03.30.437601 — molecular biology — Posted on 2021-03-30

230 Universal features of epidemic models under social distancing guidelines

Sadeghi, M.; Greene, J.; Sontag, E.

10.1101/2020.06.21.163931 — systems biology — Posted on 2021-03-30

231 A systematic structural comparison of all solved small proteins (4-6 kDa) reveals the weight of disulfide bonds in proteins' foldability

Moreira, M. H.; Almeida, F. C. L.; Domitrovic, T.; Palhano, F. L.

10.1101/2021.03.30.437752 — biochemistry — Posted on 2021-03-30

232 Whole-genome-based Helicobacter pylori geographic surveillance: a visualized and expandable webtool

Jiang, X.; XU, Z.; Zhang, T.; Li, Y.; Li, W.; Tan, H.

10.1101/2021.03.29.437451 — genomics — Posted on 2021-03-30

233 Inhibition of selective autophagy by members of the herpesvirus ubiquitin-deconjugase family

Yla-Anttila, P.; Masucci, M. G.

10.1101/2021.03.30.437649 — cell biology — Posted on 2021-03-30

234 Targeted gene sequencing with Nanopore enables rapid and accurate confirmatory diagnostic of Tilapia lake virus

Delamare-Deboutteville, J.; Taengphu, S.; Han Ming, G.; Kayansamruaj, P.; Pratim Debnath, P.; Barnes, A. C.; Wilkinson, S.; Kawasaki, M.; Vishnumurthy, M. C.; Saengchan, S.; Dong, H. T.

10.1101/2021.03.29.437503 — molecular biology — Posted on 2021-03-30

235 Impact of blood storage conditions on the transcript profile of plasma cell-free RNA

Sun, J.; Yang, X.; Wang, T.; Xing, Y.; Chen, H.; Zhu, S.; Zeng, J.; Zhou, Q.; Chen, F.; Zhang, X.; Wang, W.-J.

10.1101/2021.03.30.437637 — molecular biology — Posted on 2021-03-30

236 To catch a hijacker: abundance, evolution and genetic diversity of P4-like bacteriophage satellites

Sousa, J. M. d.; Rocha, E. P. C.

10.1101/2021.03.30.437493 — microbiology — Posted on 2021-03-30

237 Hybrid histidine kinase BinK represses Vibrio fischeri biofilm signaling at multiple developmental stages

Ludvik, D. A.; Bultman, K. M.; Mandel, M. J.

10.1101/2021.03.29.437627 — microbiology — Posted on 2021-03-30

238 Ultra-sensitive Protein-SIP to quantify activity and substrate uptake in microbiomes with stable isotopes

Kleiner, M.; Kouris, A.; Jensen, M.; Liu, Y.; McCalder, J.; Strous, M.

10.1101/2021.03.29.437612 — microbiology — Posted on 2021-03-30

239 The ascending arousal system shapes low-dimensional brain dynamics to mediate awareness of changes in intrinsic cognitive states

Munn, B. R.; Muller, E. J.; Wainstein, G.; Shine, J.

10.1101/2021.03.30.437635 — neuroscience — Posted on 2021-03-30

240 Analytical solution of linearized equations of the Morris-Lecar neuron model at large constant stimulation

Paraskevov, A. V.; Zemskova, T. S.

10.1101/869875 — neuroscience — Posted on 2021-03-30

241 Understanding binary classifier model structure based on Shapley feature interaction patterns

Zhao, B.

10.1101/2021.03.29.437591 — systems biology — Posted on 2021-03-30

242 Acitretin mitigates uroporphyrin-induced bone defects in congenital erythropoietic porphyria models

Bragazzi Cunha, J.; Elenbaas, J. S.; Maitra, D.; Kuo, N.; Azuero-Dajud, R.; Ferguson, A. C.; Griffin, M. S.; Lentz, S. I.; Shavit, J. A.; Omary, B.

10.1101/2021.03.30.437658 — pathology — Posted on 2021-03-30

243 Chaphamaparvovirus Antigen and Nucleic Acids are not Detected in Kidney Tissues from Cats with Chronic Renal Disease or Immunosuppressive Diseases

Michel, A. O.; Donovan, T.; Roediger, B.; Lee, Q.; Jolly, C. J.; Monette, S.

10.1101/2021.03.30.437777 — pathology — Posted on 2021-03-30

244 Structural characterization of the antimicrobial peptides myxinidin and WMR in bacterial membrane mimetic micelles and bicelles

Cherniavskyi, Y. K.; Oliva, R.; Stellato, M.; Del Vecchio, P.; Galdiero, S.; Falanga, A.; Dames, S. A.; Tieleman, D. P.

10.1101/2021.03.30.437760 — biochemistry — Posted on 2021-03-30

245 Recombination marks the evolutionary dynamics of a recently endogenized retrovirus

Yang, L.; Malhotra, R.; Chikhi, R.; Elleder, D.; Kaiser, T.; Rong, J.; Medvedev, P.; Poss, M.

10.1101/2021.02.24.432774 — genomics — Posted on 2021-03-30

246 Shared and disease-specific host gene-microbiome interactions across human diseases

Priya, S.; Burns, M. B.; Ward, T.; Mars, R. A. T.; Adamowicz, B.; Lock, E. F.; Kashyap, P. C.; Knights, D.; Blekhman, R.

10.1101/2021.03.29.437589 — genomics — Posted on 2021-03-30

247 Pronounced proliferation of non-beta cells in response to beta-cell mitogens in isolated human islets of Langerhans

Maachi, H.; Ghislain, J.; Tremblay, C.; Poitout, V.

10.1101/2020.10.28.359158 — cell biology — Posted on 2021-03-30

248 Caspase-2 regulates S-phase cell cycle events to protect from DNA damage accumulation independent of apoptosis

Boice, A.; Pandita, R. K.; Lopez, K.; Pourpak, M. J.; Charendoff, C. I.; Charaka, V. K.; Carisey, A. F.; Pandita, T. K.; Bouchier-Hayes, L.

10.1101/2021.03.30.437768 — cell biology — Posted on 2021-03-30

249 The Cdc42 GTPase activating protein Rga6 promotes the cortical localization of Septin

Zheng, S.; Zheng, B.; Liu, Z.; Wei, W.; Fu, C.

10.1101/2021.03.30.437639 — cell biology — Posted on 2021-03-30

250 Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics

Leppek, K.; Byeon, G. W.; Kladwang, W.; Wayment-Steele, H. K.; Kerr, C. H.; Xu, A. F.; Kim, D. S.; Topkar, V. V.; Choe, C.; Rothschild, D.; Tiu, G. C.; Wellington-Oguri, R.; Fujii, K.; Sharma, E.; Watkins, A. M.; Nicol, J. J.; Romano, J.; Tunguz, B.; Participants, E.; Barna, M.; Das, R.

10.1101/2021.03.29.437587 — molecular biology — Posted on 2021-03-30

251 Activity of Plasmodium vivax promoter elements in Plasmodium knowlesi, and a centromere-containing plasmid that expresses NanoLuc throughout the parasite life cycle

Moraes Barros, R. R.; Thawnashom, K.; Gibson, T. J.; Armistead, J. S.; Caleon, R. L.; Kaneko, M.; Kite, W. A.; Mershon, J. P.; Brockhurst, J. K.; Engels, T.; Lambert, L.; Orr-Gonzalez, S.; Adams, J. H.; Sa, J. M.; Kaneko, O.; Wellems, T.

10.1101/2021.03.30.437722 — microbiology — Posted on 2021-03-30

252 Host protease activity on bacterial pathogens promotes complement- and antibiotic-directed killing

Chen, S.; Roberts, A.-J.; Lu, F.; Cannon, C.; Qin, Q.-M.; de Figueiredo, P.

10.1101/2021.03.05.434144 — microbiology — Posted on 2021-03-30

253 Colonial choanoflagellate isolated from Mono Lake harbors a microbiome

Hake, K.; West, P. T.; McDonald, K. L.; Laundon, D.; Feng, C.; Burkhardt, P.; Richter, D. J.; Banfield, J.; King, N.

10.1101/2021.03.30.437421 — microbiology — Posted on 2021-03-30

254 Listening to bacterial Esperanto: transcriptome reprogramming in a plant beneficial rhizobacterium

Bejarano, A.; Perazzolli, M.; Pertot, I.; Puopolo, G.

10.1101/2021.03.30.437723 — microbiology — Posted on 2021-03-30

255 Members of a highly widespread bacteriophage family are hallmarks of metabolic syndrome gut microbiomes

de Jonge, P. A.; Wortelboer, K.; Scheithauer, T. P. M.; van den Born, B.-J. H.; Zwinderman, A. H.; Nobrega, F. L.; Dutilh, B. E.; Nieuwdorp, M.; Herrema, H.

10.1101/2021.03.30.437683 — microbiology — Posted on 2021-03-30

256 Comparative analysis of public RNA-sequencing data from human intestinal enteroid (HIEs) infected with enteric RNA viruses identifies universal and virus-specific epithelial responses

Cieza, R. J.; Golob, J. L.; Colacino, J. A.; Wobus, C. E.

10.1101/2021.03.30.437726 — microbiology — Posted on 2021-03-30

257 When killers become thieves: trogocytosed PD-1 inhibits NK cells in cancer

Hasim, M. S.; Marotel, M.; Hodgins, J. J.; Vulpis, E.; Shih, H.-Y.; Scheer, A.; MacMillan, O.; Alonso, F.; Burke, K.; Cook, D. P.; Petrucci, M. T.; Santoni, A.; Fallon, P.; Sharpe, A.; Sciume, G.; Veillette, A.; Zingoni, A.; McCurdy, A.; Ardolino, M.

10.1101/2020.06.26.174342 — immunology — Posted on 2021-03-30

258 DataJoint Elements: Data Workflows for Neurophysiology

Yatsenko, D.; Nguyen, T.; Shen, S.; Gunalan, K.; Turner, C. A.; Guzman, R.; Sasaki, M.; Sitonic, D.; Reimer, J.; Walker, E. Y.; Tolias, A.

10.1101/2021.03.30.437358 — neuroscience — Posted on 2021-03-30

259 Mapping Complex Brain Torque Components and Their Genetic and Phenomic Architecture in 24,112 healthy individuals

Zhao, L.; Matloff, W.; Shi, Y.; Cabeen, R. P.; Toga, A. W.

10.1101/2021.03.09.434625 — neuroscience — Posted on 2021-03-30

260 Can Stephen Curry really know? - Conscious access to outcome prediction of motor actions

Maurer, L. K.; Maurer, H.; Hegele, M.; Mueller, H.

10.1101/2021.03.30.437477 — neuroscience — Posted on 2021-03-30

261 Distinct 'driving' versus 'modulatory' influences of different visual corticothalamic pathways

Kirchgessner, M. A.; Franklin, A. D.; Callaway, E. M.

10.1101/2021.03.30.437715 — neuroscience — Posted on 2021-03-30

262 Effects on brain activity after creative mathematical reasoning when considering individual differences in cognitive ability

Karlsson Wirebring, L.; Wiklund-Hornqvist, C.; Stillesjo, S.; Granberg, C.; Lithner, J.; Andersson, M.; Nyberg, L.; Jonsson, B.

10.1101/2021.03.30.437492 — neuroscience — Posted on 2021-03-30

263 Validation and tuning of in situ transcriptomics image processing workflows with crowdsourced annotations

Vo-Phamhi, J. M.; Yamauchi, K. A.; Gomez-Sjoberg, R.

10.1101/2020.07.14.201384 — bioengineering — Posted on 2021-03-30

264 Molecular and evolutionary mechanisms of yeast thermotolerance

Abrams, M. B.; Dubin, C. A.; AlZaben, F.; Bravo, J.; Joubert, P. M.; Weiss, C. V.; Brem, R. B.

10.1101/2020.08.31.275453 — evolutionary biology — Posted on 2021-03-30

265 The Phage-shock-protein Envelope Stress Response: Discovery of Novel Partners & Evolutionary History

Ravi, J.; Anantharaman, V.; Chen, S. Z.; Datta, P.; Aravind, L.; Gennaro, M. L.

10.1101/2020.09.24.301986 — evolutionary biology — Posted on 2021-03-30

266 Nitrogenous Compound Utilization and Production of Volatile Organic Compounds among Commercial Wine Yeasts Highlight Strain-Specific Metabolic Diversity

Scott, W. T.; van Mastrigt, O.; Block, D. E.; Notebaart, R. A.; Smid, E. J.

10.1101/2021.03.29.437628 — microbiology — Posted on 2021-03-30

267 Can good broiler flock welfare prevent colonization by Campylobacter?

Rawson, T.; Colles, F.; Smith, A. L.; Stamp Dawkins, M.; Bonsall, M.

10.1101/2021.03.30.437710 — microbiology — Posted on 2021-03-30

268 HIV proviral burden, genetic diversity and dynamics in viremic controllers who subsequently initiated suppressive antiretroviral therapy

Omondi, F. H.; Sudderuddin, H.; Shahid, A.; Kinloch, N. N.; Jones, B. R.; Miller, R. L.; Tsai, O.; MacMillan, D.; Trocha, A.; Brockman, M. A.; Brumme, C. J.; Joy, J. B.; Liang, R.; Walker, B. D.; Brumme, Z. L.

10.1101/2021.03.29.437632 — microbiology — Posted on 2021-03-30

269 Severity of SARS-CoV-2 infection as a function of the interferon landscape across the respiratory tract of COVID-19 patients.

Sposito, B.; Broggi, A.; Pandolfi, L.; Crotta, S.; Ferrarese, R.; Sisti, S.; Clementi, N.; Ambrosi, A.; Liu, E.; Frangipane, V.; Saracino, L.; Marongiu, L.; Facchini, F.; Bottazzi, A.; Fossali, T.; Colombo, R.; Clementi, M.; Tagliabue, E.; Pontiroli, A.; Meloni, F.; Wack, A.; Mancini, N.; Zanoni, I.

10.1101/2021.03.30.437173 — immunology — Posted on 2021-03-30

270 Biased orientation representations can be explained by experience with non-uniform training set statistics

Henderson, M. M.; Serences, J.

10.1101/2020.07.17.209536 — neuroscience — Posted on 2021-03-30

271 Medial occipital cortex participates in a cortical network for transsaccadic feature discrimination: an fMRI paradigm

Baltaretu, B. R.; Stevens, W. D.; Freud, E.; Crawford, J. D.

10.1101/2021.03.29.437597 — neuroscience — Posted on 2021-03-30

272 Integrating reward information for prospective behaviour

Hall-McMaster, S.; Stokes, M. G.; Myers, N. E.

10.1101/2021.03.30.437719 — neuroscience — Posted on 2021-03-30

273 Seizures initiate in zones of relative hyperexcitation in a zebrafish epilepsy model

Niemeyer, J. E.; Gadamsetty, P.; Chun, C.; Sylvester, S.; Lucas, J. P.; Ma, H.; Schwartz, T. H.; Aksay, E.

10.1101/2021.03.30.437750 — neuroscience — Posted on 2021-03-30

274 A novel theoretical framework for simultaneous measurement of excitatory and inhibitory conductances

Muller-Komorowska, D.; Parabucki, A.; Elyasaf, G.; Katz, Y.; Beck, H.; Lampl, I.

10.1101/2021.03.30.437555 — neuroscience — Posted on 2021-03-30

275 Perception of effort during an isometric contraction is influenced by prior muscle lengthening or shortening

Kozlowski, B.; Pageaux, B.; Hubbard, E. H.; St. Peters, B.; Millar, P. J.; Power, G. A.

10.1101/2021.03.29.437599 — neuroscience — Posted on 2021-03-30

276 Enhancing neuronal plasticity through intracranial theta burst stimulation in the human sensorimotor cortex.

Herrero, J. L.; Smith, A.; Mishra, A.; Markowitz, N. L.; Mehta, A. D.; Bickel, S.

10.1101/2021.03.29.437614 — neuroscience — Posted on 2021-03-30

277 Identification of Target Objects from Gaze Behavior during a Virtual Navigation Task

Enders, L. R.; Smith, R. J.; Gordon, S. M.; Ries, A. J.; Touryan, J.

10.1101/2021.03.30.437718 — neuroscience — Posted on 2021-03-30

278 A stochastic model of hippocampal synaptic plasticity with geometrical readout of enzyme dynamics

Rodrigues, Y. E.; Tigaret, C. M.; Marie, H.; O'Donnell, C.; Veltz, R.

10.1101/2021.03.30.437703 — neuroscience — Posted on 2021-03-30

279 Quantifying control circuit regulation in the human brain.

Kumar, R.; Strey, H. H.; Mujica-Parodi, L. R.

10.1101/2021.03.30.437729 — neuroscience — Posted on 2021-03-30

280 Rapid characterization of spike variants via mammalian cell surface display

Javanmardi, K.; Chou, C.-W.; Terrace, C.; Annapareddy, A.; Kaoud, T. S.; Guo, Q.; Lutgens, J.; Zorkic, H.; Horton, A. P.; Gardner, E. C.; Nguyen, G.; Boutz, D. R.; Goike, J.; Voss, W. N.; Kuo, H.-C.; Dalby, K. N.; Gollihar, J. D.; Finkelstein, I. J.

10.1101/2021.03.30.437622 — biochemistry — Posted on 2021-03-30

281 Sequence analysis of SARS-CoV-2 in nasopharyngeal samples from patients with COVID-19 illustrates population variation and diverse phenotypes, placing the in vitro growth properties of B.1.1.7 and B.1.351 lineage viruses in context.

Prince, T.; Dong, X.; Penrice-Randal, R.; Randle, N.; Hartley, C.; Goldswain, H.; Jones, B.; Semple, M. G.; Baillie, J. K.; Openshaw, P. J. M.; Turtle, L.; ISARIC4C Investigators, ; Hughes, G.; Anderson, E.; Patterson, E. I.; Druce, J.; Screaton, G.; Carroll, M.; Stewart, J. P.; Hiscox, J. A.

10.1101/2021.03.30.437704 — microbiology — Posted on 2021-03-30

282 16S rRNA Amplicon Sequencing of Bagworm Metisa plana Walker (Lepidoptera: Psychidae)

Ting, A. C. J.; ZAINAL ABIDIN, C. M. R.; HAMID, N. H.; Azzam, G.; Salim, H.

10.1101/2021.03.30.437633 — microbiology — Posted on 2021-03-30

283 A recombinant receptor-binding domain in trimeric form generates completely protective immunity against SARS-CoV-2 infection in nonhuman primates

Yang, L.; Tian, D.; Han, J.-b.; Fan, W.; Zhang, Y.; Li, Y.; Sun, W.; Wei, Y.; Tian, X.; Yu, D.-d.; Feng, X.-l.; Cheng, G.; Zheng, Y.-t.; Bi, Y.; Liu, W.

10.1101/2021.03.30.437647 — immunology — Posted on 2021-03-30

284 A MALDI-TOF assay identifies nilotinib as an inhibitor of inflammation in acute myeloid leukemia and multiple myeloma.

Heap, R. E.; Marin-Rubio, J. L.; Heunis, T.; Duenas, M. E.; Inns, J.; Saxty, B.; Trost, M.

10.1101/2021.03.29.437557 — cancer biology — Posted on 2021-03-30

285 Identification of biomarkers and pathways of mitochondria in sepsis patients

Yuan, G.

10.1101/2021.03.29.437586 — immunology — Posted on 2021-03-30

286 An eye gaze-modulated neural source highly impaired in autism spectrum disorder

Lio, G.; Corazzol, M.; Fadda, R.; Doneddu, G.; Demily, C.; Sirigu, A.

10.1101/2021.03.29.433074 — neuroscience — Posted on 2021-03-30

287 The unbiased estimation of r2 between two sets of noisy neural responses

Pospisil, D.; Bair, W. A.

10.1101/2021.03.29.437413 — neuroscience — Posted on 2021-03-30

288 Relationship between constitutive and acute gene regulation, and physiological and behavioral responses, mediated by the neuropeptide PACAP

Bakalar, D.; Sweat, S.; Drossel, G.; Jiang, S. Z.; Samal, B. S.; Stroth, N.; Xu, W.; Zhang, L.; Zhang, H.; Eiden, L. E.

10.1101/2021.03.29.437579 — neuroscience — Posted on 2021-03-30

289 Evidence for glutamine synthetase function in mouse spinal cord oligodendrocytes

Ben Haim, L.; Schirmer, L.; Zulji, A.; Sabeur, K.; Tiret, B.; Chang, S.; Lamers, W. H.; Chaumeil, M. M.; Rowitch, D. H.

10.1101/2021.03.29.437580 — neuroscience — Posted on 2021-03-30

290 A stochastic pooling motif mediates information transfer from receptor assemblies into NF-κB

Cruz, J. A.; Mokashi, C. S.; Kowalczyk, G. J.; Guo, Y.; Zhang, Q.; Gupta, S.; Schipper, D. L.; Lee, R. E. C.

10.1101/2021.03.29.437543 — systems biology — Posted on 2021-03-30

291 Plasticity of maternal environment dependent expression-QTLs of tomato seeds

Sterken, M. G.; Nijveen, H.; van Zanten, M.; Jimenez-Gomez, J.; Geshnizjani, N.; Willems, L. A. J.; Rienstra, J.; Hilhorst, H. W. M.; Ligterink, W.; Snoek, B. L.

10.1101/2021.03.29.437558 — plant biology — Posted on 2021-03-30

292 Biallelic mutations in cancer genomes reveal local mutational determinants

Demeulemeester, J.; Dentro, S. C.; Gerstung, M.; Van Loo, P.

10.1101/2021.03.29.437407 — cancer biology — Posted on 2021-03-30

293 LKB1 inactivation modulates chromatin accessibility to drive metastatic progression

Pierce, S. E.; Granja, J. M.; Corces, M. R.; Brady, J. J.; Tsai, M. K.; Pierce, A. B.; Tang, R.; Chu, P.; Feldser, D. M.; Chang, H.; Bassik, M. C.; Greenleaf, W. J.; Winslow, M. M.

10.1101/2021.03.29.437560 — cancer biology — Posted on 2021-03-30

294 Evidence Graphs: Supporting Transparent and FAIR Computation, with Defeasible Reasoning on Data, Methods and Results

Al Manir, S.; Niestroy, J.; Levinson, M. A.; Clark, T.

10.1101/2021.03.29.437561 — bioinformatics — Posted on 2021-03-30

295 DISTEMA: distance map-based estimation of single protein model accuracy with attentive 2D convolutional neural network

Chen, X.; Cheng, J.

10.1101/2021.03.29.437573 — bioinformatics — Posted on 2021-03-30

296 Structural characterization of NORAD reveals a stabilizing role of spacers and two new repeat units.

Chorostecki, U.; Saus, E.; Gabaldon, T.

10.1101/2021.03.29.437547 — genomics — Posted on 2021-03-30

297 Self-organization of a doubly asynchronous irregular network state for spikes and bursts

Vercruysse, F.; Naud, R.; Sprekeler, H.

10.1101/2021.03.29.437548 — neuroscience — Posted on 2021-03-30

298 Genetic Architecture of Kernel Compositional Variation in a Maize Diversity Panel

Renk, J.; Gilbert, A.; Hattery, T.; O'Connor, C.; Monnahan, P.; Anderson, N.; Waters, A.; Eickholt, D.; Flint-Garcia, S.; Yandeau-Nelson, M.; Hirsch, C.

10.1101/2021.03.29.436703 — plant biology — Posted on 2021-03-30

299 Cytoskeleton-extracellular matrix interaction is required to maintain mitochondrial Ca2+ control in mouse skeletal muscle fibre

Gineste, C.; Henriksson, S.; Hernandez, A.; Cheng, A. J.; Chaillou, T.; Vorrink, S. U.; Youhanna, S.; Buttgereit, A.; Schneidereit, D.; Friedrich, O.; Hultenby, K.; Bruton, J. D.; Ivarsson, N.; Sandblad, L.; Lauschke, V. M.; Westerblad, H.

10.1101/2021.03.29.437546 — physiology — Posted on 2021-03-30

300 Changing in the hierarchical organization of local information dynamics during motor decision in the premotor cortex of primates

Bardella, G.; Giarrocco, F.; Andujar, M.; Brunamonti, E.; Pani, P.; Ferraina, S.

10.1101/2021.03.15.435381 — neuroscience — Posted on 2021-03-30

301 Rescue of aberrant huntingtin palmitoylation ameliorates mutant huntingtin-induced toxicity

Lemarie, F. L.; Caron, N. S.; Sanders, S. S.; Schmidt, M. E.; Nguyen, Y. T. N.; Ko, S.; Xu, X.; Pouladi, M. A.; Martin, D. D. O.; Hayden, M. R.

10.1101/2021.03.26.437210 — neuroscience — Posted on 2021-03-30

302 Bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquitos

Viswanatha, R.; Mameli, E.; Rodiger, J.; Merckaert, P.; Feitosa-Suntheimer, F.; Colpitts, T. M.; Mohr, S. E.; Hu, Y.; Perrimon, N.

10.1101/2021.03.29.437496 — genetics — Posted on 2021-03-30

303 Manifestations of genetic risk for Alzheimer's Disease in the blood: a cross-sectional multi-omic analysis in healthy adults aged 18-90+

Heath, L. M.; Earls, J. C.; Magis, A. T.; Kornilov, S. A.; Lovejoy, J. C.; Funk, C. C.; Rappaport, N.; Logsdon, B. A.; Mangravite, L. M.; Kunkle, B. W.; Martin, E.; Naj, A. C.; Ertekin-Taner, N.; Golde, T.; Hood, L.; Price, N. D.; Alzheimer's Disease Genetics Consortium,

10.1101/2021.03.26.437267 — genetics — Posted on 2021-03-30

304 Development of a yeast-based assay for bioavailable phosphorous

Shepherd, H. A. M.; Trentman, M. T.; Tank, J. L.; Praner, J.; Cervantes, A.; Chaudhary, P.; Gezelter, J.; Marrs, A. J.; Myers, K. A.; Welsh, J. R.; Wu, Y.-F. O.; Goodson, H. V.

10.1101/2021.02.28.433264 — ecology — Posted on 2021-03-30

305 Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing

Hu, C.; Chu, C.; Liu, L.; Wang, C.; Jin, S.; Yang, R.; Rung, S.; Li, J.; Qu, Y.; Man, Y.

10.1101/2020.08.10.243659 — immunology — Posted on 2021-03-30

306 Cortical processing of reference in language revealed by computational models

Li, J.; Wang, S.; Luh, W.-M.; Pylkkanen, L.; Yang, Y.; Hale, J.

10.1101/2020.11.24.396598 — neuroscience — Posted on 2021-03-30

307 Neuropredictome: a data-driven predictome for cognitive, psychiatric, medical, and lifestyle factors on the brain

Sultan, S. F.; Mujica-Parodi, L. R.; Skiena, S.

10.1101/2020.12.07.415091 — neuroscience — Posted on 2021-03-30

308 Patient-specific network connectivity combined with a next generation neural mass model to test clinical hypothesis of seizurepropagation

Gerster, M.; Taher, H.; Skoch, A.; Hlinka, J.; Guye, M.; Bartolomei, F.; Jirsa, V.; Zakharova, A.; Olmi, S.

10.1101/2021.01.15.426839 — neuroscience — Posted on 2021-03-30

309 The trade-off between color and size in lizards' conspicuous tails

Guidi, R. d. S.; Sao-Pedro, V. d. A.; Ramos-Silva, H.; Costa, G. C.; Pessoa, D. M. A.

10.1101/2021.03.29.437563 — animal behavior and cognition — Posted on 2021-03-30

310 Multimodal genomic markers predict immunotherapy response in the head and neck squamous cell carcinoma

Kumar, G.; South, A. P.; Curry, J. M.; Linnenbach, A.; Harshyne, L. A.; Ertel, A.; Fortina, P.; Luginbuhl, A.

10.1101/2021.03.30.437691 — genomics — Posted on 2021-03-30

311 Combined Nanopore and Single-Molecule Real-Time Sequencing Survey of Human Betaherpesvirus 5 Transcriptome

Kakuk, B.; Tombacz, D.; Balazs, Z.; Moldovan, N.; Csabai, Z.; Torma, G.; Megyeri, K.; Snyder, M.; Boldogkoi, Z.

10.1101/2021.03.30.437686 — genomics — Posted on 2021-03-30

312 Non-parallel morphological divergence following colonization of a new host plant

Nilsson, K. J.; Ortega, J.; Friberg, M.; Runemark, A.

10.1101/2021.03.30.436984 — evolutionary biology — Posted on 2021-03-30

313 Up and to the light: intra- and interspecific variability of photo- and geo-tactic oviposition preferences in genus Trichogramma

Perez, G.; Burte, V.; Ayed, F.; Groussier, G.; van Oudenhove, l.; Mailleret, L.; calcagno, v.

10.1101/2021.03.30.437671 — ecology — Posted on 2021-03-30

314 GCN5 Maintains Muscle Integrity by Acetylating YY1 to Promote Dystrophin Expression

Addicks, G. C.; Zhang, H.; Ryu, D.; Vasam, G.; Marshall, P. L.; Green, A. E.; Patel, S.; Kang, B. E.; Kim, D.; Katsyuba, E.; Williams, E. G.; Renaud, J.-M.; Auwerx, J.; Menzies, K. J.

10.1101/2021.03.29.436986 — cell biology — Posted on 2021-03-30

315 Inhibition of PLK1-dependent EBNA2 phosphorylation promotes lymphomagenesis in EBV-infected mice.

Zhang, X.; Schuhmachers, P.; Mourao, A.; Giansanti, P.; Murer, A.; Thumann, S.; Kuklik-Roos, C.; Beer, S.; Hauck, S. M.; Hammerschmidt, W.; Küppers, R.; Küster, B.; Raab, M.; Strebhardt, K.; Sattler, M.; Münz, C.; Kempkes, B.

10.1101/2021.03.29.437455 — cancer biology — Posted on 2021-03-30

316 Effect of malaria parasite shape on its alignment at erythrocyte membrane

Dasanna, A. K.; Hillringhaus, S.; Gompper, G.; Fedosov, D. A.

10.1101/2021.03.29.437549 — biophysics — Posted on 2021-03-30

317 Detection of pathogenic splicing events from RNA-sequencing data using dasper

Zhang, D.; Reynolds, R. H.; Garcia-Ruiz, S.; Gustavsson, E. K.; Sethi, S.; Aguti, S.; Barbosa, I. A.; Collier, J. J.; Holden, H.; McFarland, R.; Muntoni, F.; Olahova, M.; Poulton, J.; Simpson, M.; Pitceathly, R. D.; Taylor, R. W.; Zhou, H.; Deshpande, C.; Botia, J. A.; Collado-Torres, L.; Ryten, M.

10.1101/2021.03.29.437534 — bioinformatics — Posted on 2021-03-30

318 The innate immune kinase TBK1 directly increases mTORC2 activity and downstream signaling to Akt

Tooley, A. S.; Kazyken, D.; Bodur, C.; Gonzalez, I. E.; Fingar, D. C.

10.1101/2021.03.30.437707 — biochemistry — Posted on 2021-03-30

319 Whole-Genome Sequencing on 220 Alfalfa (Medicago sativa L.) Accessions Identified Association of DREB1C Gene with Fall Dormancy Height

Zhang, F.; Kang, J.; Long, R.; Li, M.; Sun, Y.; Wang, Z.; Zhang, Z.; Yang, Q.

10.1101/2021.03.29.437533 — genomics — Posted on 2021-03-30

320 Invertebrate methylomes provide insight into mechanisms of environmental tolerance and reveal methodological biases

Trigg, S. A.; Venkataraman, Y. R.; Gavery, M.; Roberts, S. B.; Bhattacharya, D.; Downey-Wall, A.; Eirin-Lopez, J. M.; Johnson, K. M.; Lotterhos, K. E.; Puritz, J. B.; Putnam, H. M.

10.1101/2021.03.29.437539 — genomics — Posted on 2021-03-30

321 Ghost lineages deceive introgression tests and call for a new null hypothesis

Tricou, T.; Tannier, E.; de Vienne, D. M.

10.1101/2021.03.30.437672 — evolutionary biology — Posted on 2021-03-30

322 Untangling the complexity of priority effects in multi-species communities

Song, C.; Fukami, T.; Saavedra, S.

10.1101/2021.03.29.437541 — ecology — Posted on 2021-03-30

323 A constitutively expressed fluorescence ubiquitin cell cycle indicator (FUCCI) in axolotls for studying tissue regeneration

Duerr, T. J.; Jeon, E. K.; Wells, K. M.; Villanueva, A.; Seifert, A. W.; McCusker, C. D.; Monaghan, J. R.

10.1101/2021.03.30.437716 — developmental biology — Posted on 2021-03-30

324 Exploiting synergistic interactions of Medicago sativa L. and Paraburkholderia tropica for enhanced biodegradation of diesel fuel hydrocarbons

Eze, M. O.; Thiel, V.; Hose, G. C.; George, S. C.; Daniel, R.

10.1101/2021.03.30.437699 — microbiology — Posted on 2021-03-30

325 The DBL-1/TGF-β signaling pathway regulates pathogen-specific innate immune responses in C. elegans

Madhu, B.; Gumienny, T. L.

10.1101/2021.03.30.437693 — immunology — Posted on 2021-03-30

326 Dynamical processing of orientation precision in the primary visual cortex

Ladret, H. J.; Cortes, N.; Ikan, L.; Chavane, F.; Casanova, C.; Perrinet, L. U.

10.1101/2021.03.30.437692 — neuroscience — Posted on 2021-03-30

327 Coupling brain cerebrovascular oscillations and CSF flow during wakefulness: An fMRI study

Yang, H.-C. S.; Inglis, B.; Talavage, T. M.; Vijayakrishnan Nair, V.; Yao, J. F.; Fitzgerald, B.; Schwichtenberg, A. J.; Tong, Y.

10.1101/2021.03.29.437406 — neuroscience — Posted on 2021-03-30

328 In vitro teratogenicity testing using a 3D, embryo-like gastruloid system

Mantziou, V.; Baillie-Benson, P.; Jaklin, M.; Kustermann, S.; Martinez Arias, A.; Moris, N.

10.1101/2021.03.30.437698 — pharmacology and toxicology — Posted on 2021-03-30

329 Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome

Troskie, R.-L.; Jafrani, Y.; Mercer, T. R.; Ewing, A. D.; Faulkner, G. J.; Cheetham, S. W.

10.1101/2021.03.29.437610 — genomics — Posted on 2021-03-30

330 Epigenetic models predict age and aging in plains zebras and other equids

Larison, B.; Pinho, G. M.; Haghani, A.; Zoller, J. A.; Li, C. Z.; Finno, C. J.; Farrell, C.; Kaelin, C. B.; Barsh, G.; Wooding, B.; Robeck, T. R.; Maddox, D.; Pellegrini, M.; Horvath, S.

10.1101/2021.03.29.437607 — developmental biology — Posted on 2021-03-30

331 The C. elegans PTCHD homolog PTR-4 is required for proper organization of the pre-cuticular apical extracellular matrix

Cohen, J. D.; Cadena del Castillo, C. E.; Kaech, A.; Spang, A.; Sundaram, M. V.

10.1101/2021.03.30.437696 — cell biology — Posted on 2021-03-30

332 Reproducible Coactivation Patterns of Functional Brain Networks Reveal the Aberrant Dynamic State Transition in Schizophrenia

Yang, H.; Zhang, H.; Di, X.; Wang, S.; Meng, C.; Tian, L.; Biswal, B. B.

10.1101/2021.03.29.437611 — neuroscience — Posted on 2021-03-30

333 A T-cell independent universal cellular therapy strategy through antigen depletion

Li, D.; Wang, W.; Xie, S.; Ge, M.; Wang, R.; Xu, Q.; Sun, Y.; Zhu, J.; Liu, H.

10.1101/2021.03.29.437606 — cancer biology — Posted on 2021-03-30

334 The parasite Schistocephalus solidus secretes proteins with putative host manipulation functions

Berger, C. S.; Laroche, J.; Maaroufi, H.; Martin, H.; Moon, K.-M.; Landry, C.; Foster, L.; Aubin-Horth, N.

10.1101/2020.02.03.932509 — genomics — Posted on 2021-03-30

335 Conjugative plasmid transfer is limited by prophages but can be overcome by high conjugation rates

Igler, C.; Schwyter, L.; Gehrig, D.; Wendling, C. C.

10.1101/2021.03.29.437513 — evolutionary biology — Posted on 2021-03-30

336 Dietary cardenolides enhance growth and change the direction of the fecundity-longevity trade-off in milkweed bugs (Heteroptera: Lygaeinae)

Pokharel, P.; Steppuhn, A.; Petschenka, G.

10.1101/2021.03.29.437508 — ecology — Posted on 2021-03-30

337 Natural variants in SARS-CoV-2 S protein pinpoint structural and functional hotspots; implications for prophylaxis and therapeutics strategies

Pokhrel, S.; Kraemer, B. R.; Burkholz, S.; Mochly-Rosen, D.

10.1101/2021.01.04.425340 — molecular biology — Posted on 2021-03-30

338 Type 2 innate immunity regulates hair follicle homeostasis to control Demodex pathosymbionts

Ricardo-Gonzalez, R. R.; Kotas, M. E.; Tenvooren, I.; Marquez, D. M.; Fassett, M. S.; Lee, J.; Daniel, S. G.; Bittinger, K.; Diaz, R. E.; Fraser, J. S.; Ansel, K. M.; Spitzer, M. H.; Liang, H.-E.; Locksley, R. M.

10.1101/2021.03.29.437438 — immunology — Posted on 2021-03-30

339 Sexual maturation in Atlantic salmon male parr may be triggered both in early spring and late summer under standard farming conditions

Ciani, E.; von Krogh, K.; Nourizadeh-Lillabadi, R.; Mayer, I.; Fontaine, R.; Weltzien, F.-A.

10.1101/2021.03.29.437499 — physiology — Posted on 2021-03-30

340 Molecular dynamics simulation study of effects of key mutations in SARS-CoV-2 on protein structures

Lon, J. R.; Xi, B.; Zhong, B.; Zheng, Y.; Guo, P.; Chen, Z.; Qiu, R.; Zhang, S.; Du, H.

10.1101/2021.02.03.429495 — bioinformatics — Posted on 2021-03-30

341 An interpretable meta-clustering framework for single-cell RNA-Seq data integration and evaluation

Hu, Z.; Ahmed, A. A.; Yau, C.

10.1101/2021.03.29.437525 — bioinformatics — Posted on 2021-03-30

342 Mechanically Activated Extracellular Vesicle Functionalised Melt Electrowritten Materials for Bone Regeneration: A Mechano-Biomimetic Scaffold

Eichholz, K.; Federici, A.; Riffault, M.; Woods, I.; Mahon, O.; O'Driscoll, L.; Hoey, D. A.

10.1101/2021.03.29.437528 — bioengineering — Posted on 2021-03-30

343 ID-Seg: An Accurate and Reliable Infant Deep learning Segmentation Framework for Limbic Structures

Wang, Y.; Haghpanah, F. S.; Zhang, X.; Santamaria, K.; Alves, G. K. d. C. A.; Bruno, E.; Aw, N.; Maddocks, A.; Duarte, C. S.; Monk, C. E.; Laine, A.; Posner, J.

10.1101/2021.03.29.437045 — bioengineering — Posted on 2021-03-30

344 NRF1 Association with AUTS2-Polycomb Mediates Specific Gene Activation in the Brain

Liu, S.; Aldinger, K. A.; Cheng, C. V.; Kiyama, T.; Dave, M.; McNamara, H. K.; Caraffi, S. G.; Ivanovski, I.; Errichiello, E.; Zweier, C.; Zuffardi, O.; Schneider, M.; Papavasiliou, A. S.; Perry, M. S.; Cho, M. T.; Weber, A.; Swale, A.; Badea, T. C.; Mao, C.-A.; Garavelli, L.; Dobyns, W. B.; Reinberg, D.

10.1101/2021.03.30.437620 — biochemistry — Posted on 2021-03-30

345 Context-dependent transcriptional regulation of microglial proliferation

Belhocine, S.; Xavier, A. M.; Distefano-Gagne, F.; Fiola, S.; Rivest, S.; Gosselin, D.

10.1101/2021.03.29.436988 — genomics — Posted on 2021-03-30

346 lassosum2: an updated version complementing LDpred2

Prive, F.; Vilhjalmsson, B. J.; Mak, T. S. H.

10.1101/2021.03.29.437510 — genetics — Posted on 2021-03-30

347 Decomposing virulence to understand bacterial clearance in persistent infections

Acuna Hidalgo, B.; Silva, L. M.; Regoes, R. R.; Franz, M.; Armitage, S. A. O.

10.1101/2021.03.29.437521 — evolutionary biology — Posted on 2021-03-30

348 Modeling pulsed evolution and time-independent variation improves the confidence level of ancestral and hidden state predictions in continuous traits

Gao, Y.; Wu, M.

10.1101/2021.03.29.437517 — evolutionary biology — Posted on 2021-03-30

349 Human brain organoids assemble functionally integrated bilateral optic vesicles

Gabriel, E.; Albanna, W.; Pasquini, G.; Ramani, A.; Josipovic, N.; Mariappan, A.; Schinzel, F.; Karch, C. M.; Bao, G.; Gottardo, M.; Hescheler, J.; Persico, V.; Rizzoli, S. O.; Altmüller, J.; Callaini, G.; Papantonis, A.; Goureau, O.; Busskamp, V.; Schneider, T.; Gopalakrishnan, J.

10.1101/2021.03.30.437506 — developmental biology — Posted on 2021-03-30

350 Astrocytes are implicated in BDNF-mediated enhancement of hippocampal long-term potentiation

Gomes, J. I.; Jesus, J.; Macau, R.; Goncalves-Ribeiro, J.; Pinto, S.; Pina, C. C.; Armada-Moreira, A.; Sebastiao, A. M.; Vaz, S. H.

10.1101/2021.03.30.437538 — neuroscience — Posted on 2021-03-30

351 Don't Stress, It's Under Control: Neural Correlates of Stressor Controllability in Humans

Meine, L. E.; Meier, J.; Meyer, B.; Wessa, M.

10.1101/2021.03.30.437657 — neuroscience — Posted on 2021-03-30

352 Delta- and theta-band cortical tracking and phase-amplitude coupling to sung speech by infants

Attaheri, A.; Ni Choisdealbha, A.; Di Liberto, G.; Rocha, S.; Brusini, P.; Mead, N.; Olawole-Scott, H.; Boutris, P.; Gibbon, S.; Williams, I.; Grey, C.; Flanagan, S.; Goswami, U.

10.1101/2020.10.12.329326 — neuroscience — Posted on 2021-03-30

353 The chaos in calibrating crop models

Wallach, D.; Palosuo, T.; Thorburn, P.; Hochman, Z.; Gourdain, E.; Andrianasolo, F.; Asseng, S.; Basso, B.; Buis, S.; Crout, N.; Dibari, C.; Dumont, B.; Ferrise, R.; Gaiser, T.; Garcia, C.; Gayler, S.; Ghahramani, A.; Hiremath, S.; Hoek, S.; Horan, H.; Hoogenboom, G.; Huang, M.; Jabloun, M.; Jansson, P.-E.; Jing, Q.; Justes, E.; Kersebaum, K. C.; Klosterhalfen, A.; Launay, M.; Lewan, E.; Luo, Q.; Maestrini, B.; Mielenz, H.; Moriondo, M.; Nariman Zadeh, H.; Padovan, G.; Olesen, J. E.; Poyda, A.; Priesack, E.; Pullens, J. W. M.; Qian, B.; Schuetze, N.; Shelia, V.; Souissi, A.; Specka, X.; Srivas

10.1101/2020.09.12.294744 — plant biology — Posted on 2021-03-30

354 Live-dead assay on unlabeled cells using phase imaging with computational specificity

Hu, C.; He, S.; Lee, Y. J.; He, Y.; Kong, E. M.; Li, H.; Anastasio, M. A.; Popescu, G.

10.1101/2020.10.28.359554 — bioengineering — Posted on 2021-03-30

355 Interactions, information and emergence: Exploring task allocation in ant colonies using network analysis

Swain, A.; Williams, S. D.; Di Felice, L. J.; Hobson, E. A.

10.1101/2021.03.29.437501 — animal behavior and cognition — Posted on 2021-03-30

356 Fast ontogenetic growth drives steep evolutionary scaling of metabolic rate

Norin, T.

10.1101/2021.03.29.437465 — ecology — Posted on 2021-03-30

357 A novel splice variant of human TGF-β type II receptor encodes a soluble protein and its Fc-tagged version prevents liver fibrosis in vivo.

Bertolio, M. S.; La Colla, A.; Carrea, A.; Romo, A.; Canziani, G.; Echarte, S. M.; Campisano, S.; Barletta, G. P.; Monzon, A. M.; Rodriguez, T. M.; Chisari, A. N.; Dewey, R. A.

10.1101/2021.03.01.433173 — cell biology — Posted on 2021-03-30

358 Single-cell analysis of the human pancreas in type 2 diabetes using multi-spectral imaging mass cytometry

Wu, M.; Lee, M. Y. Y.; Traum, D.; Schug, J.; Kusmartseva, I.; Atkinson, M. A.; Consortium, H.; Kaestner, K. H.

10.1101/2021.03.29.437504 — molecular biology — Posted on 2021-03-30

359 Innate immune signaling in trophoblast and decidua organoids defines differential antiviral defenses at the maternal-fetal interface

Yang, L.; Megli, C.; Coyne, C. B.

10.1101/2021.03.29.437467 — immunology — Posted on 2021-03-30

360 PD-1 expression on NK cells can be related to cytokine stimulation and tissue residency

Wagner, A. K.; Kadri, N.; Tibbit, C.; van de Ven, K.; Bagawath-Singh, S.; Oliinyk, D.; LeGresly, E.; Campbell, N.; Trittel, S.; Riese, P.; Sandalova, T.; Achour, A.; Karre, K.; Chambers, B. J.

10.1101/2021.03.29.437486 — immunology — Posted on 2021-03-30

361 Lysophophatidyl-choline 16:0 mediates persistent joint pain through Acid-Sensing Ion Channel 3: preclinical and clinical evidences

10.1101/2021.03.29.437487 — neuroscience — Posted on 2021-03-30

362 Shared and unique properties of place cells in anterior cingulate cortex and hippocampus

Bota, A.; Goto, A.; Tsukamoto, S.; Schmidt, A.; Wolf, F.; Luchetti, A.; Nakai, J.; Hirase, H.; Hayashi, Y.

10.1101/2021.03.29.437441 — neuroscience — Posted on 2021-03-30

363 Acetylcholine Signaling Genes are Required for Cocaine-Stimulated Egg Laying in Caenorhabditis elegans

Emerson, S. D.; Hay, M.; Smith, M.; Granger, R.; Blauch, D.; Snyder, N.; El Bejjani, R.

10.1101/2020.11.24.396333 — neuroscience — Posted on 2021-03-30

364 Explaining face representation in the primate brain using different computational models

Chang, L.; Egger, B.; Vetter, T.; Tsao, D.

10.1101/2020.06.07.111930 — neuroscience — Posted on 2021-03-30

365 Identification of candidate genes for self-compatibility in perennial ryegrass (Lolium perenne L.)

Cropano, C.; Manzanares, C.; Yates, S.; Copetti, D.; Do Canto, J.; Lübberstedt, T.; Koch, M.; Studer, B.

10.1101/2021.03.29.437398 — plant biology — Posted on 2021-03-30

366 Mass recalibration for desorption electrospray ionization mass spectrometry imaging using endogenous reference ions.

Inglese, P.; Huang, H.; Wu, V.; Lewis, M. R.; Takats, Z.

10.1101/2021.03.29.437482 — bioinformatics — Posted on 2021-03-30

367 Transcriptional activity and epigenetic regulation of transposable elements in the symbiotic fungus Rhizophagus irregularis

Dallaire, A.; Manley, B. F.; Wilkens, M.; Bista, I.; Quan, C.; Evangelisti, E.; Ramakrishna, N. B.; Schornack, S.; Butter, F.; Paszkowski, U.; Miska, E. A.

10.1101/2021.03.30.436303 — genomics — Posted on 2021-03-30

368 Fifty generations of amitosis: tracing asymmetric allele segregation in polyploid cells with single-cell DNA sequencing

Vitali, V.; Rothering, R.; Catania, F.

10.1101/2021.03.29.437473 — genomics — Posted on 2021-03-30

369 Attentional dynamics of efficient codes

Mlynarski, W. F.; Tkacik, G.

10.1101/2021.03.29.437459 — neuroscience — Posted on 2021-03-30

370 Biasing RNA coarse-grained folding simulations with Small--Angle X--ray Scattering (SAXS) data

Mazzanti, L.; Alferkh, L.; Frezza, E.; Pasquali, S.

10.1101/2021.03.29.437449 — biophysics — Posted on 2021-03-30

371 KinaFrag explores the kinase-ligand fragment interaction space for selective kinase inhibitor discovery

Wang, Z.-Z.; Shi, X.-X.; Wang, F.; Hao, G.-F.; Yang, G.-F.

10.1101/2021.03.28.436965 — bioinformatics — Posted on 2021-03-30

372 Structural variant selection for high-altitude adaptation using single-molecule long-read sequencing

Shi, J.; Jia, Z.; Zhao, X.; Sun, J.; Liang, F.; Park, M.; Zhao, C.; Wang, X.; Chen, Q.; Song, X.; Yu, K.; Jia, Q.; Wang, D.; Xiao, Y.; Liu, Y.; Wu, S.; Zhong, Q.; Wu, J.; Cui, S.; Bo, X.; Wu, Z.; Kellis, M.; He, K.

10.1101/2021.03.27.436702 — genomics — Posted on 2021-03-30

373 Predictive Neural Computations Support Spoken Word Recognition: Evidence from MEG and Competitor Priming

Wang, Y. C.; Sohoglu, E.; Gilbert, R. A.; Henson, R. N.; Davis, M. H.

10.1101/2020.07.01.182717 — neuroscience — Posted on 2021-03-30

374 From work stress to disease: A computational model

Benthem de Grave, R.; Hasselman, F.; Bijleveld, E.

10.1101/2020.03.12.988527 — physiology — Posted on 2021-03-30

375 The level of synovial human VEGFA, IL-8 and MIP-1α correlate with truncation of lubricin glycans in osteoarthritis

Huang, S.; Thomsson, K. A.; Jin, C.; Ryberg, H.; Das, N.; Struglics, A.; Rolfson, O.; Björkman, L. I.; Eisler, T.; Schimdt, T. A.; Jay, G. D.; Krawetz, R.; Karlsson, N. G.

10.1101/2021.03.11.434779 — pathology — Posted on 2021-03-30

376 A new parallel high-pressure packing system enables rapid multiplexed production of capillary columns

Mueller-Reif, J. B.; Hansen, F. M.; Schweizer, L.; Treit, P. V.; Geyer, P. E.; Mann, M.

10.1101/2021.02.26.433033 — biochemistry — Posted on 2021-03-30

377 Establishment and Resilience of Transplanted Gut Microbiota in Aged Mice

Wang, Y.; Tang, J.; Lv, Q.; Tan, Y.; Dong, X.; Liu, H.; Zhao, N.; He, Z.; Kou, Y.; Tan, Y.; Liu, X.-a.; Wang, L.; Liu, Y.-Y.; Dai, L.

10.1101/2021.03.18.435923 — microbiology — Posted on 2021-03-30

378 Revisiting the role of Toxoplasma gondii ERK7 in the maintenance and stability of the apical complex

Soldati-Favre, D.; Dos Santos Pacheco, N.; Tosetti, N.; Krishnan, A.; Haase, R.

10.1101/2021.03.22.436543 — microbiology — Posted on 2021-03-30

379 Human cerebral cortex networks use expanding and contracting state dynamic to shape cortical functions

Willumsen, A.; Midtgaard, J.; Jespertsen, B.; Hansen, C. K. K.; Lam, S. N.; Hansen, S.; Kupers, R.; Fabricius, M. E.; Litman, M.; Pinborg, L.; Tascon-Vidarte, J. D.; Sabers, A.; Roland, P. E.

10.1101/2020.09.24.309468 — neuroscience — Posted on 2021-03-30

380 Individual-Specific Areal-Level Parcellations Improve Functional Connectivity Prediction of Behavior

Kong, R.; Yang, Q.; Gordon, E.; Xue, A.; Yan, X.; Orban, C.; Zuo, X.-N.; Spreng, N.; Ge, T.; Holmes, A.; Eickhoff, S.; Yeo, B. T. T.

10.1101/2021.01.16.426943 — neuroscience — Posted on 2021-03-30

381 Spatiotemporal control of cell cycle acceleration during axolotl spinal cord regeneration

Cura Costa, E.; Otsuki, L.; Rodrigo Albors, A.; Tanaka, E. M.; Chara, O.

10.1101/2020.02.10.941443 — systems biology — Posted on 2021-03-30

382 EMT changes actin cortex rheology in a cell-cycle dependent manner

Hosseini, K.; Frenzel, A.; Fischer-Friedrich, E.

10.1101/2020.12.15.422849 — biophysics — Posted on 2021-03-30

383 The complete mitochondrial genome of a parthenogenetic ant Monomorium triviale (Hymenoptera: Formicidae)

Idogawa, N.; Lee, C.-C.; Yang, C.-C. S.; Dobata, S.

10.1101/2021.03.02.433554 — genomics — Posted on 2021-03-30

384 Effect of Stapling on the Thermodynamics of mdm2-p53 Binding

Maity, A.; Choudhury, A. R.; Chakrabarti, R.

10.1101/2020.12.28.424518 — biochemistry — Posted on 2021-03-30

385 Oxytocin receptor activation does not mediate associative fear deficits in a Williams Syndrome model

Nygaard, K. R.; Swift, R. G.; Glick, R. M.; Wagner, R. E.; Maloney, S. E.; Gould, G. G.; Dougherty, J. D.

10.1101/2021.03.29.437431 — animal behavior and cognition — Posted on 2021-03-30

386 Identification of neural progenitor cells and their progeny reveals long distance migration in the developing octopus brain

Deryckere, A.; Styfhals, R.; Elagoz, A. M.; Maes, G. E.; Seuntjens, E.

10.1101/2021.03.29.437526 — developmental biology — Posted on 2021-03-30

387 The 3D-atlas builder: a dynamic and expandable 3D-tool for monitoring the changes in the neuronal differentiation domain during hindbrain morphogenesis

Blanc, M.; Udina, F.; Pujades, C.

10.1101/2021.03.29.437592 — developmental biology — Posted on 2021-03-30

388 Tbx1, a 22q11.2-encoded gene, is a link between alterations in fimbria myelination and cognitive speed in mice

Hiramoto, T.; Sumiyoshi, A.; Yamauchi, T.; Tanigaki, K.; Shi, Q.; Kang, G.; Ryoke, R.; Nonaka, H.; Enomoto, S.; Izumi, T.; Bhat, M. A.; Kawashima, R.; Hiroi, N.

10.1101/2021.03.29.437581 — neuroscience — Posted on 2021-03-30

389 Complex Computation from Developmental Priors

Barabasi, D. L.; Beynon, T.

10.1101/2021.03.29.437584 — neuroscience — Posted on 2021-03-30

390 Catch me if you can: Least myelinated white matter develops fastest during early infancy

Grotheer, M.; Rosenke, M.; Wu, H.; Kular, H.; Querdasi, F. R.; Natu, V.; Yeatman, J. D.; Grill-spector, K.

10.1101/2021.03.29.437583 — neuroscience — Posted on 2021-03-30

391 Prolonged impacts of past agriculture and overgrazing on soil fungal communities in restored forests

Tatsumi, S.; Matsuoka, S.; Fujii, S.; Makoto, K.; Osono, T.; Isbell, F.; Mori, A. S.

10.1101/2020.05.09.086025 — ecology — Posted on 2021-03-29

392 EHMT2 Controls Transcriptional Noise and the Developmental Switch after Gastrulation in the Mouse Embryo

Zeng, T.-B.; Pierce, N.; Liao, J.; Singh, P.; Zhou, W.; Szabo, P. E.

10.1101/2021.03.29.437567 — developmental biology — Posted on 2021-03-29

393 Conserved and context-dependent roles for Pdgfrb signaling during zebrafish vascular mural cell development

Ando, K.; Shih, Y.-H.; Ebarasi, L.; Grosse, A.; Portman, D.; Chiba, A.; Mattonet, K.; Gerri, C.; Stainier, D. Y. R.; Mochizuki, N.; Fukuhara, S.; Betsholtz, C.; Lawson, N. D.

10.1101/2021.03.29.437552 — developmental biology — Posted on 2021-03-29

394 A cryo-ET survey of intracellular compartments within mammalian axons

Foster, H. E.; Ventura Santos, C.; Carter, A. P.

10.1101/2021.03.29.437454 — cell biology — Posted on 2021-03-29

395 Atg39 links and deforms the outer and inner nuclear membranes in selective autophagy of the nucleus

Mochida, K.; Otani, T.; Katsumata, Y.; Kirisako, H.; Kakuta, C.; Kotani, T.; Nakatogawa, H.

10.1101/2021.03.29.437603 — cell biology — Posted on 2021-03-29

396 A cryo-ET study of microtubules in axons

Foster, H. E.; Ventura Santos, C.; Carter, A. P.

10.1101/2021.03.29.437471 — cell biology — Posted on 2021-03-29

397 Tracking dynamic adjustments to decision making and performance monitoring processes in conflict tasks

Feuerriegel, D. C.; Jiwa, M.; Turner, W. F.; Andrejevic, M.; Hester, R.; Bode, S.

10.1101/2019.12.19.883447 — neuroscience — Posted on 2021-03-29

398 Evolutionary trade-offs at the Arabidopsis WRR4A resistance locus underpin alternate Albugo candida recognition specificities

Castel, B.; Fairhead, S.; Furzer, O. J.; Redkar, A.; Wang, S.; Cevik, V.; Holub, E.; Jones, J. D.

10.1101/2021.03.29.437434 — plant biology — Posted on 2021-03-29

399 Stepwise maturation of the peptidyl transferase region of human mitoribosomes

Lenarcic, T.; Jaskolowski, M.; Leibundgut, M.; Scaiola, A.; Schoenhut, T.; Saurer, M.; Lee, R.; Rackham, O.; Filipovska, A.; Ban, N.

10.1101/2021.03.29.437532 — biochemistry — Posted on 2021-03-29

400 Fluorescence lifetime imaging of pH along the secretory pathway

Linders, P.; ter Beest, M.; van den Bogaart, G.

10.1101/2021.03.29.437519 — cell biology — Posted on 2021-03-29

401 Correlative Organelle Microscopy: fluorescence guided volume electron microscopy of intracellular processes

Loginov, S.; Fermie, J.; Fokkema, J.; Agronskaia, A. V.; de Heus, C.; Blab, G. A.; Klumperman, J.; Gerritsen, H. C.; Liv, N.

10.1101/2021.03.29.437317 — cell biology — Posted on 2021-03-29

402 Combining experiments and in silico modeling to infer the role of adhesion and proliferation on the collective dynamics of cells

Melo, H. P. M.; Raquel Maia, F.; Nunes, A. S.; Reis, R. L.; Oliveira, J. M.; Araujo, N. A. M.

10.1101/2021.03.29.437400 — cell biology — Posted on 2021-03-29

403 Description and comparison of PIMS-TS innate cell signature and immunophenotype with a cohort of healthy children, severe viral and bacterial infections and Kawasaki Disease.

Garcia-Salido, A.; Leoz-Gordillo, I.; Gonzalez Bravin, A.; Garcia-Teresa, M. A.; Martinez-de-Azagra-Garde, A.; Iglesias-Bouzas, M. I.; Cabrero-Hernandez, M.; de - Lama - Caro - Paton, G.; Unzueta - Roch, J. L.; Castillo-Robleda, A.; Ramirez-Orellana, M.; Nieto-Moro, M.

10.1101/2021.03.29.437479 — immunology — Posted on 2021-03-29

404 Linguistic processing of task-irrelevant speech at a Cocktail Party

Har-shai Yahav, P.; Zion Golumbic, E.

10.1101/2020.11.08.373746 — neuroscience — Posted on 2021-03-29

405 Only two out of five articles by New Zealand researchers are free-to-access: a multiple API study of access, citations, cost of Article Processing Charges (APC), and the potential to increase the proportion of open access

White, R. K. A.; Angelo, A.; Fitchett, D. J.; Fraser, M.; Hayes, L.; Howie, J.; Richardson, E.; White, B. D.

10.1101/2020.06.23.164004 — scientific communication and education — Posted on 2021-03-29

406 COVID-19 and the abrupt shift to remote learning: Impact on grades and perceived learning for undergraduate biology students

Supriya, K.; Mead, C.; Anbar, A. D.; Caulkins, J. L.; Collins, J. P.; Cooper, K. M.; LePore, P. C.; Lewis, T.; Pate, A.; Scott, R. A.; Brownell, S. E.

10.1101/2021.03.29.437480 — scientific communication and education — Posted on 2021-03-29

407 Direct induction of hemogenic endothelial progenitors from hPSCs by defined factors revealed by single-cell transcriptome analysis

Randolph, L. N.; Jiang, Y.; Chang, Y.; Bao, X.; Lian, X. L.

10.1101/2021.03.18.435636 — bioengineering — Posted on 2021-03-29

408 Notch signaling represses cone photoreceptor formation through the regulation of retinal progenitor cell states

Chen, X.; Emerson, M. M.

10.1101/2020.11.09.375832 — developmental biology — Posted on 2021-03-29

409 On the joint effect of endogenous spatial attention and defocus blur on acuity: attentional limit to the resolving power of the eye

de Lestrange, E.

10.1101/2020.08.25.266700 — neuroscience — Posted on 2021-03-29

410 Staphylococcus aureus α-toxin induces acid sphingomyelinase release from a human endothelial cell line

Krones, D.; Rühling, M.; Becker, K. A.; Kunz, T. C.; Sehl, C.; Paprotka, K.; Gulbins, E.; Fraunholz, M. J.

10.1101/2021.03.29.437456 — microbiology — Posted on 2021-03-29

411 A gain and dynamic range independent index to quantify spillover spread to aid panel design in flow cytometry

Bhowmick, D.; Diepen, F. V.; Pfauth, A.; Tissier, R.; Ratliff, M.

10.1101/2020.10.31.363150 — immunology — Posted on 2021-03-29

412 Thalamus and claustrum control parallel layer 1 circuits in retrosplenial cortex

Brennan, E. K.; Jedrasiak-Cape, I.; Kailasa, S.; Rice, S. P.; Sudhakar, S. K.; Ahmed, O. J.

10.1101/2020.09.17.300863 — neuroscience — Posted on 2021-03-29

413 Deciphering Brassica plant defence responses to cabbage white butterfly egg-associated molecular patterns

Caarls, L.; Bassetti, N.; van Doesburg, F.; Verbaarschot, P.; van Loon, J. J. A.; Schranz, M. E.; Fatouros, N. E.

10.1101/2021.03.29.437462 — plant biology — Posted on 2021-03-29

414 Active Participation of Membrane Lipids in Inhibition of Multidrug Transporter P-Glycoprotein

Kapoor, k.; Pant, S.; Tajkhorshid, E.

10.1101/2020.11.15.383794 — biophysics — Posted on 2021-03-29

415 dGPredictor: Automated fragmentation method for metabolic reaction free energy prediction and de novo pathway design

Wang, L.; Upadhyay, V.; Maranas, C. D.

10.1101/2021.03.15.434460 — bioinformatics — Posted on 2021-03-29

416 Assessing heterogeneity in spatial data using the HTA index with applications to spatial transcriptomics and imaging

Levy-Jurgenson, A.; Tekpli, X.; Yakhini, Z.

10.1101/2021.02.28.433250 — bioinformatics — Posted on 2021-03-29

417 Reference plasmid pHXB2_D is an HIV-1 molecular clone that exhibits identical LTRs and a single integration site indicative of an HIV provirus

Gener, A. R.; Zou, W.; Foley, B. T.; Hyink, D. P.; Klotman, P. E.

10.1101/611848 — genomics — Posted on 2021-03-29

418 Inferring the Total-Evidence Timescale of Marattialean Fern Evolution in the Face of Model Sensitivity

May, M. R.; Contreras, D. L.; Sundue, M. A.; Nagalingum, N. S.; Looy, C. V.; Rothfels, C. J.

10.1101/2020.09.25.313643 — evolutionary biology — Posted on 2021-03-29

419 Genome architecture shapes evolutionary adaptation to DNA replication stress

Fumasoni, M.; Murray, A.

10.1101/2020.12.17.423282 — evolutionary biology — Posted on 2021-03-29

420 Mast seeding promotes evolution of scatter-hoarding

Zwolak, R.; Clements, D.; Sih, A.; Schreiber, S.

10.1101/698761 — ecology — Posted on 2021-03-29

421 Dispensing a synthetic green leaf volatile to two plant species in a common garden differentially alters physiological responses and herbivory

Freundlich, G. E.; Shields, M.; Frost, C. J.

10.1101/370692 — ecology — Posted on 2021-03-29

422 An 18S V4 rDNA metabarcoding dataset of protist diversity in the Atlantic inflow to the Arctic Ocean, through the year and down to 1000 m depth.

Egge, E.; Elferink, S.; Vaulot, D.; John, U.; Bratbak, G.; Larsen, A.; Edvardsen, B.

10.1101/2021.03.29.437475 — ecology — Posted on 2021-03-29

423 Training-induced bioenergetic improvement in human skeletal muscle is associated with non-stoichiometric changes in the mitochondrial proteome without reorganization of respiratory chain content

Granata, C.; Caruana, N. J.; Botella, J.; Jamnick, N. A.; Huynh, K.; Kuang, J.; Janssen, H. A.; Reljic, B.; Mellett, N. A.; Laskowski, A.; Stait, T. L.; Frazier, A. E.; Coughlan, M. T.; Meikle, P. J.; Thorburn, D. R.; Stroud, D. A.; Bishop, D. J.

10.1101/2021.02.19.431993 — cell biology — Posted on 2021-03-29

424 SpeciesRax: A tool for maximum likelihood species tree inference from gene family trees under duplication, transfer, and loss.

Morel, B.; Schade, P.; Lutteropp, S.; Williams, T. A.; Szöllösi, G. J.; Stamatakis, A.

10.1101/2021.03.29.437460 — molecular biology — Posted on 2021-03-29

425 Fasciola hepatica fatty acid binding protein (Fh12) induces apoptosis and tolerogenic properties in murine bone marrow derived dendritic cells

Ruiz-Jimenez, C.; Celias, D. P.; Valdes, B.; Ramos-Perez, W. D.; Cervi, L. P.; Espino, A. M.

10.1101/2021.03.29.437545 — immunology — Posted on 2021-03-29

426 Systematic analysis of CD39, CD103, CD137 and PD-1 as biomarkers for naturally occurring tumor antigen-specific TILs

Eiva, M. A.; Omran, D. K.; Chacon, J.; Powell, D. J.

10.1101/2021.03.29.437255 — immunology — Posted on 2021-03-29

427 Tracking the contribution of inductive bias to individualized internal models

Török, B.; Nagy, D. G.; Kiss, M. M.; Janacsek, K.; Nemeth, D.; Orban, G.

10.1101/2020.06.22.163295 — neuroscience — Posted on 2021-03-29

428 Multiple sounds degrade the frequency representation in monkey inferior colliculus

Willett, S. M.; Groh, J. M.

10.1101/2020.07.03.187021 — neuroscience — Posted on 2021-03-29

429 Astrocyte-neuron interplay is critical for Alzheimer's disease pathogenesis and is rescued by TRPA1 channel blockade

Paumier, A.; Boisseau, S.; Pernet-Gallay, K.; Buisson, A.; Albrieux, M.

10.1101/2021.03.29.437466 — neuroscience — Posted on 2021-03-29

430 Analysis of the Human Connectome Data Supports the Notion of a "Common Model of Cognition" for Human and Human-Like Intelligence

Stocco, A.; Sibert, C.; Steine-Hanson, Z.; Koh, N.; Laird, J.; Lebiere, C.; Rosenbloom, P.

10.1101/703777 — neuroscience — Posted on 2021-03-29

431 Chromatin accessibility dynamics of neurogenic niche cells reveal a reversible decline in neural stem cell migration during aging

Yeo, R. W.; Zhou, O. Y.; Zhong, B.; Sharmin, M.; Ruetz, T. J.; Kundaje, A.; Dunn, A. R.; Brunet, A.

10.1101/2021.03.29.437585 — neuroscience — Posted on 2021-03-29

432 SARS-CoV-2, a threat to marine mammals? A study from Italian seawaters

Audino, T.; Grattarola, C.; Centelleghe, C.; Peletto, S.; Giorda, F.; Florio, C. L.; Caramelli, M.; Bozzetta, M. E.; Mazzariol, S.; Di Guardo, G.; Lauriano, G.; Casalone, C.

10.1101/2021.03.29.437540 — pathology — Posted on 2021-03-29

433 Enrichment of SARS-CoV-2 entry factors and interacting intracellular genes in peripheral immune cells

Devaprasad, A.; Pandit, A.

10.1101/2021.03.29.437515 — bioinformatics — Posted on 2021-03-29

434 Self-Supervised Representation Learning of Protein Tertiary Structures (PtsRep) and Its Implications for Protein Engineering

Luo, J.; Cai, Y.; Wu, J.; Cai, H.; Yang, X.; Lin, Z.

10.1101/2020.12.22.423916 — bioinformatics — Posted on 2021-03-29

435 Low-Cost, Modular Modification to a Desktop 3D Printer for General Purpose Gel/Paste Extrusion & Direct Ink Writing

Leech, D. J.; Lightfoot, S.; Huson, D.; Stratakos, A. C.

10.1101/2021.03.10.434735 — bioengineering — Posted on 2021-03-29

436 COVID-19 dominant D614G mutation in the SARS-CoV-2 spike protein desensitizes its temperature-dependent denaturation

Yang, T.-J.; Yu, P.-Y.; Chang, Y.-C.; Kuo, C.-W.; Khoo, K.-H.; Hsu, S.-T. D.

10.1101/2021.03.28.437426 — biochemistry — Posted on 2021-03-29

437 Intrinsic Degradation of the Type-II Antitoxin ParD from Pseudomonas aeruginosa

Snead, K. J.; Bourne, C. R.

10.1101/2021.03.29.437564 — biochemistry — Posted on 2021-03-29

438 Reciprocal allostery arising from a bi-enzyme assembly controls aromatic amino acid biosynthesis in Prevotella nigrescens

Bai, Y.; Parker, E. J.

10.1101/2021.03.29.437529 — biochemistry — Posted on 2021-03-29

439 Distal and proximal cis-regulatory elements sense X-chromosomal dosage and developmental state at the Xist locus

Gjaltema, R. A.; Schwammle, T.; Kautz, P.; Robson, M.; Schoepflin, R.; Ravid Lustig, L.; Brandenburg, L.; Dunkel, I.; Vechiatto, C.; Ntini, E.; Mutzel, V.; Schmiedel, V.; Marsico, A.; Mundlos, S.; Schulz, E. G.

10.1101/2021.03.29.437476 — genomics — Posted on 2021-03-29

440 Evidence for shared ancestry between Actinobacteria and Firmicutes bacteriophages

Koert, M.; Lopez-Perez, J.; Mattson, C.; Caruso, S. M.; Erill, I.

10.1101/842583 — genomics — Posted on 2021-03-29

441 Gene expression in the developing nemertean brain indicates convergent evolution of complex brains in Spiralia

Gasiorowski, L.; Boerve, A.; Cherneva, I. A.; Orus-Alcalde, A.; Hejnol, A.

10.1101/2021.03.29.437382 — evolutionary biology — Posted on 2021-03-29

442 Revisiting the evolutionary history of pigs via de novo mutation rate estimation by deep genome sequencing on a three-generation pedigree

Zhang, M.; Yang, Q.; Ai, H.; Huang, L.

10.1101/2021.03.29.437103 — evolutionary biology — Posted on 2021-03-29

443 Dual control exerted by dopamine in blood-progenitor cell cycle regulation in Drosophila

Mukherjee, T.; Kapoor, A.; Padmavathi, A.

10.1101/2021.03.29.437463 — developmental biology — Posted on 2021-03-29

444 A novel domain within the CIL regulates egress of IFITM3 from the Golgi and prevents its deleterious accumulation in this apparatus

Zhong, L.; Uzbekov, R.; Journo, C.; Roingeard, P.; CIMARELLI, A.

10.1101/2021.03.29.437470 — cell biology — Posted on 2021-03-29

445 Clinically relevant mutations of mycobacterial GatCAB inform regulation of translational fidelity

Li, Y.-Y.; Cai, R.-J.; Yang, J.-Y.; Hendrickson, T. L.; Xiang, Y.; Javid, B.

10.1101/2021.03.29.437598 — molecular biology — Posted on 2021-03-29

446 Phosphorylation of myosin A regulates Plasmodium sporozoite motility and is essential for efficient malaria transmission

Ripp, J.; Smyrnakou, X.; Neuhoff, M.-T.; Frischknecht, F.

10.1101/2021.03.29.437488 — molecular biology — Posted on 2021-03-29

447 Cis-regulatory elements of the cholinergic gene locus in the silkworm Bombyx mori

Banzai, K.; Izumi, S.

10.1101/2021.03.29.437568 — molecular biology — Posted on 2021-03-29

448 Critical contribution of 3' non-seed base pairing to the in vivo function of the evolutionarily conserved let-7a microRNA

Duan, Y.; Veksler-Lublinsky, I.; Ambros, V.

10.1101/2021.03.29.437276 — molecular biology — Posted on 2021-03-29

449 The CTEXT complex in Saccharomyces cerevisiae plays a crucial role in degrading distinct sets of aberrant mRNAs by the nuclear exosome

Saha, U.; Gaine, R.; Paira, S.; Das, S.; Das, B.

10.1101/2021.03.29.437469 — molecular biology — Posted on 2021-03-29

450 HPMCP-coated microcapsules containing the Ctx(Ile21)-Ha antimicrobial peptide reduces the mortality rate caused by resistant Salmonella Enteritidis in poultry

Roque Borda, C. A.; Pereira, L. P.; Lopes Guastalli, E. A.; Soares, N. M.; Mac-Lean, P. A.; Salgado, D. D.; Meneguin, A. B.; Chorilli, M.; Vicente, E. F.

10.1101/2021.03.29.437537 — microbiology — Posted on 2021-03-29

451 High-resolution single-molecule long-fragment rRNA gene amplicon sequencing for uncultured bacterial and fungal communities

Fang, C.; Sun, X.; Fan, F.; Zhang, X.; Wang, O.; Zheng, H.; Peng, Z.; Luo, X.; Chen, A.; Zhang, W.; Drmanac, R.; Peters, B. A.; Song, Z.; Kristiansen, K.

10.1101/2021.03.29.437457 — microbiology — Posted on 2021-03-29

452 The small acid-soluble proteins of Clostridioides difficile are important for UV resistance and serve as a check point for sporulation.

Nerber, H. N.; Sorg, J. A.

10.1101/2021.03.29.437554 — microbiology — Posted on 2021-03-29

453 A lipid nanoparticle RBD-hFc mRNA vaccine protects hACE2 transgenic mice against lethal SARS-CoV-2 infection

Elia, U.; Rotem, S.; Bar-Haim, E.; Ramishetti, S.; Naidu, G. S.; Gur, D.; Aftalion, M.; Israeli, M.; Bercovich-Kinori, A.; Alcalay, R.; Makdasi, E.; Chitlaru, T.; Rosenfeld, R.; Israely, T.; Melamed, S.; Abutbul Ionita, I.; Danino, D.; Peer, D.; Cohen, O.

10.1101/2021.03.29.436639 — microbiology — Posted on 2021-03-29

454 Plant phenology influences rhizosphere microbial community and is accelerated by serpentine microorganisms in Plantago erecta

Igwe, A.; Quasem, B.; Liu, N.; Vannette, R.

10.1101/2021.03.29.437500 — microbiology — Posted on 2021-03-29

455 Alpha-synuclein alters the faecal viromes of rats in a gut-initiated model of Parkinson's disease

Stockdale, S. R.; Draper, L. A.; O'Donovan, S.; Barton, W.; O'Sullivan, O.; Volpicelli-Daley, L. A.; Sullivan, A.; O'Neill, C.; Hill, C.

10.1101/2021.03.29.437468 — microbiology — Posted on 2021-03-29

456 An improved assembly of the Albugo candida Ac2V genome reveals the expansion of the "CCG" class of effectors

Furzer, O. J.; Cevik, V.; Fairhead, S.; Bailey, K.; Redkar, A.; Schudoma, C.; MacLean, D.; Holub, E. B.; Jones, J. D. G.

10.1101/2021.03.29.437041 — plant biology — Posted on 2021-03-29

457 Somatic DNA demethylation generates tissue-specific methylation states and impacts flowering time

Williams, B. P.; Bechen, L. A.; Pohlmann, D. A.; Gehring, M.

10.1101/2021.03.29.437569 — plant biology — Posted on 2021-03-29

458 Bacterial retrons enable precise gene editing in human cells

Zhao, B.; Chen, S.-A. A.; Lee, J.; Fraser, H. B.

10.1101/2021.03.29.437260 — bioengineering — Posted on 2021-03-29

459 Bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquitos

Viswanatha, R.; Mameli, E.; Rodiger, J.; Merckaert, P.; Feitosa-Suntheimer, F.; Colpitts, T. M.; Mohr, S. E.; Hu, Y.; Perrimon, N.

10.1101/2021.03.29.437496 — genetics — Posted on 2021-03-29

460 Phase Resolution of Heterozygous Sites in Diploid Genomes is Important to Phylogenomic Analysis under the Multispecies Coalescent Model

Huang, J.; Bennett, J.; Flouris, T.; Leache, A. D.; Yang, Z.

10.1101/2021.03.29.437575 — evolutionary biology — Posted on 2021-03-29

461 Multi-omic meta-analysis of transcriptomes and the bibliome uncovers GPR146 as the novel hypoxia-inducible gene

Ono, Y.; Bono, H.

10.1101/2021.03.29.433661 — bioinformatics — Posted on 2021-03-29

462 Competitive SNP-LAMP probes for rapid and robust single-nucleotide polymorphism detection

Hyman, L. B.; Christopher, C. R.; Romero, P. A.

10.1101/2021.03.29.437576 — bioengineering — Posted on 2021-03-29

463 Proteasome autophagy is specifically regulated and requires factors dispensible for general autophagy

Waite, K. A.; Burrris, A.; Vontz, G.; Lang, A.; Roelofs, J.

10.1101/2021.03.26.437055 — biochemistry — Posted on 2021-03-29

464 Degradation of visible autumn icons and conservation opportunities: trends in deciduous forest loss in the contiguous US

Dreiss, L. M.; Malcom, J. W.

10.1101/2021.03.29.437570 — ecology — Posted on 2021-03-29

465 Intergenerational metabolic priming by sperm piRNAs

Lempradl, A.; Kugelberg, U.; Iconomou, M.; Beddows, I.; Nätt, D.; Casas, E.; Örkenby, L.; Enders, L.; Gutierrez Martinez, A.; Lushchak, O.; Boonen, E.; Rückert, T.; Sabev, M.; Roth, M. G. L.; Vavouri, T.; Öst, A.; Pospisilik, J. A.

10.1101/2021.03.29.436592 — developmental biology — Posted on 2021-03-29

466 An ERK5-KLF2 signalling module regulates early embryonic gene expression dynamics and stem cell rejuvenation

Brown, H. A.; Williams, C. A.; Zhou, H.; Rios-Szwed, D.; Fernandez-Alonso, R.; Mansoor, S.; McMulkin, L.; Toth, R.; Gourlay, R.; Peltier, J.; Dieguez-Martinez, N.; Trost, M.; Lizcano, J. M.; Stavridis, M.; Findlay, G. M.

10.1101/2021.03.29.435803 — developmental biology — Posted on 2021-03-29

467 Self-Supervised Deep-Learning Encodes High-Resolution Features of Protein Subcellular Localization

Kobayashi, H.; Cheveralls, K. C.; Leonetti, M.; Royer, L. A.

10.1101/2021.03.29.437595 — cell biology — Posted on 2021-03-29

468 A disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesis

Robertson, N.; Shchepachev, V.; Wright, D.; Turowski, T. W.; Spanos, C.; Helwak, A.; Zamoyska, R.; Tollervey, D.

10.1101/2021.03.29.437572 — cell biology — Posted on 2021-03-29

469 Bayesian metamodeling of complex biological systems across varying representations

Raveh, B.; Sun, L.; White, K. L.; Sanyal, T.; Tempkin, J.; Zheng, D.; Bharath Pilla, K.; Singla, J.; Wang, C.; Zha, J.; Li, A.; Graham, N. A.; Kesselman, C.; Stevens, R. C.; Sali, A.

10.1101/2021.03.29.437574 — cell biology — Posted on 2021-03-29

470 OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Cho, N. H.; Cheveralls, K. C.; Brunner, A.-D.; Kim, K.; Michaelis, A. C.; Raghavan, P.; Kobayashi, H.; Savy, L.; Li, J. Y.; Canaj, H.; Kim, J. Y. S.; Setwart, E. M.; Gnann, C.; McCarthy, F.; Cabrera, J. P.; Brunetti, R. M.; Chhun, B. B.; Dingle, G.; Hein, M. Y.; Huang, B.; Mehta, S. B.; Weissman, J. S.; Gomez-Sjoberg, R.; Itzhak, D. N.; Royer, L. A.; Mann, M.; Leonetti, M. D.

10.1101/2021.03.29.437450 — cell biology — Posted on 2021-03-29

471 Sulfate adenylyl transferase kinetics and mechanisms of metabolic inhibitors of microbial sulfate respiration

Carlson, H. K.; Youngblut, M. D.; Redford, S. A.; Williamson, A. J.; Coates, J.

10.1101/2021.03.29.436835 — microbiology — Posted on 2021-03-29

472 A synthetic receptor platform enables rapid and portable monitoring of liver dysfunction via engineered bacteria.

Chang, H.-J.; Zuniga, A.; Conejero, I.; Voyvodic, P. L.; Gracy, J.; Fajardo-Ruiz, E.; Cohen-Gonsaud, M.; Cambray, G.; Pageaux, G.-P.; Meszaros, M.; Meunier, L.; Bonnet, J.

10.1101/2021.03.24.436753 — synthetic biology — Posted on 2021-03-29

473 The Arabidopsis WRR4A and WRR4B paralogous NLR proteins both confer recognition of multiple Albugo candida effectors

Redkar, A.; Cevik, V.; Bailey, K.; Furzer, O. J.; Fairhead, S.; Borhan, M. H.; Holub, E. B.; Jones, J. D. G.

10.1101/2021.03.29.436918 — plant biology — Posted on 2021-03-29

474 Benchmarking small-variant genotyping in polyploids

Cooke, D. P.; Wedge, D. C.; Lunter, G.

10.1101/2021.03.29.436766 — bioinformatics — Posted on 2021-03-29

475 Phase separation of RNA-binding protein promotes polymerase engagement and transcription

Shao, W.; Bi, X.; Gao, B.; Wu, J.; Pan, Y.; Yin, Y.; Liu, Z.; Zhang, W.; Jiang, X.; Ren, W.; Xu, Y.; Wu, Z.; Wang, K.; Zhan, G.; Lu, J.; Han, X.; Li, T.; Li, G.; Wang, J.; Deng, H.; Li, B.; Shen, X.

10.1101/2021.03.26.436939 — biochemistry — Posted on 2021-03-29

476 Ultra-low Input Circulating Tumor DNA Detection by MED-Amp in Early-Stage Pancreatic Cancer

Pratt, E. D.; Zhen, D. B.; Cowan, R. W.; Cameron, H.; Schradle, K.; Manning, S. L.; Gunchick, V.; Simeone, D. M.; Sahai, V.; Rhim, A. D.

10.1101/2021.03.28.437388 — genomics — Posted on 2021-03-29

477 Modeling Substrate Coordination to Zn-Bound Angiotensin Converting Enzyme 2

Fatouros, P. R.; Roy, U.; Sur, S.

10.1101/2021.03.27.437352 — biophysics — Posted on 2021-03-29

478 Preliminary report on SARS-CoV-2 Spike mutation T478K

Di Giacomo, S.; Mercatelli, D.; Rakhimov, A.; Giorgi, F. M.

10.1101/2021.03.28.437369 — evolutionary biology — Posted on 2021-03-29

479 SARS-CoV-2 variant B.1.1.7 caused HLA-A2+ CD8+ T cell epitope mutations for impaired cellular immune response

Xiao, C.; Mao, L.; Wang, Z.; Zhu, G.; Gao, L.; Su, J.; Chen, X.; Yuan, J.; Hu, Y.; Luo, O. J.; Wang, P.; Chen, G.

10.1101/2021.03.28.437363 — immunology — Posted on 2021-03-29

480 Sexually dimorphic placental responses to maternal SARS-CoV-2 infection

Bordt, E. A.; Shook, L. L.; Atyeo, C.; Pullen, K. M.; De Guzman, R. M.; Meinsohn, M.-C.; Chauvin, M.; Fischinger, S.; Yockey, L. J.; James, K.; Lima, R.; Yonker, L. M.; Fasano, A.; Brigida, S.; Bebell, L. M.; Roberts, D. J.; Pepin, D.; Huh, J. R.; Bilbo, S. D.; Li, J. Z.; Kaimal, A.; Schust, D.; Gray, K. J.; Lauffenburger, D.; Alter, G.; Edlow, A. G.

10.1101/2021.03.29.437516 — immunology — Posted on 2021-03-29

481 Age-dependent appearance of SARS-CoV-2 entry cells in mouse chemosensory systems reflects COVID-19 anosmia and ageusia symptoms.

Brechbuhl, J.; Wood, D.; Bouteiller, S.; Lopes, A. C.; Verdumo, C.; Broillet, M.-C.

10.1101/2021.03.29.437530 — neuroscience — Posted on 2021-03-29

482 Coordinating With a Robot Partner Affects Action Monitoring Related Neural Processing

Czeszumski, A.; Gert, A. L.; Keshava, A.; Ghadirzadeh, A.; Kalthoff, T.; Ehinger, B. V.; Tiessen, M.; Björkman, M.; Kragic, D.; König, P.

10.1101/2021.03.26.437133 — neuroscience — Posted on 2021-03-29

483 Turnip crinkle virus targets host ATG8 proteins to attenuate antiviral autophagy

Shukla, A.; Hoffmann, G.; Hofius, D.; Hafren, A.

10.1101/2021.03.28.437395 — plant biology — Posted on 2021-03-29

484 An additional area of apple domestication with crop-wild gene flow, and also cultivation of the local wild apple, in the Caucasus

Bina, H.; Yousefzadeh, H.; Venon, A.; Remoue, C.; Rousselet, A.; Falque, M.; Faramarzi, S.; GIRAUD, T.; Hossainpour, B.; Hamid, A.; Gabrielyan, I.; Nersesyan, A.; Cornille, A. A.

10.1101/2021.03.28.437401 — evolutionary biology — Posted on 2021-03-29

485 Fast model-based ordination with copulas

Popovic, G. C.; Hui, F. K. C.; Warton, D. I.

10.1101/2021.03.28.437086 — ecology — Posted on 2021-03-29

486 Predictors of zoonotic potential in helminths

Majewska, A. A.; Huang, T.; Han, B. A.; Drake, J. M.

10.1101/2021.03.28.437423 — ecology — Posted on 2021-03-29

487 Maxent modeling for predicting the potential distribution of global talaromycosis

Wei, W.; He, J.; Ning, C.; Xu, B.; Wang, G.; Lai, J.; Jiang, J.; Ye, L.; Liang, H.

10.1101/2021.03.28.437430 — ecology — Posted on 2021-03-29

488 Unconventional Translation Initiation Factor EIF2A is required for Drosophila spermatogenesis

Lowe, D. D.; Montell, D.

10.1101/2021.03.28.437419 — developmental biology — Posted on 2021-03-29

489 A TBP-independent mechanism for RNA Polymerase II transcription

Kwan, J. Z. J.; Nguyen, T. F.; Budzynski, M. A.; Cui, J.; Price, R. M.; Teves, S. S.

10.1101/2021.03.28.437425 — molecular biology — Posted on 2021-03-29

490 Asymmetric structures and conformational plasticity of the uncleaved full-length human immunodeficiency virus (HIV-1) envelope glycoprotein trimer

Zhang, S.; Wang, K.; Wei Li, W.; Nguyen, H. T.; Chen, S.; Lu, M.; Go, E. P.; Ding, H.; Steinbock, R. T.; Desaire, H.; Kappes, J. C.; Sodroski, J. G.; Mao, Y.

10.1101/2021.03.28.437443 — molecular biology — Posted on 2021-03-29

491 Early invasion of uropathogenic Escherichia coli into the bladder wall by solitary bacteria that are protected from antibiotics and neutrophil swarms in an organoid model

Sharma, K.; Thacker, V. V.; Dhar, N.; Signorino-Gelo, F.; Cabrer, M. C.; Dubois, A.; Mullenders, J.; Knott, G.; Clevers, H.; McKinney, J. D.

10.1101/2020.10.29.358622 — microbiology — Posted on 2021-03-29

492 Associations Between Task-Related Modulation of Motor-Evoked Potentials and EEG Event-Related Desynchronization in Children with ADHD

Ewen, J. B.; Puts, N. A.; Mostofsky, S. H.; Horn, P. S.; Gilbert, D. L.

10.1101/2021.03.28.437305 — neuroscience — Posted on 2021-03-29

493 Transformation from local image contrast to location-independent numerosity tuning in human extrastriate cortex

Paul, J. M.; van Ackooij, M.; ten Cate, T. C.; Harvey, B. M.

10.1101/2021.03.28.437364 — neuroscience — Posted on 2021-03-29

494 SARS CoV-2 nucleocapsid protein forms condensates with viral genomic RNA

Jack, A.; Ferro, L. S.; Trnka, M. J.; Wehri, E.; Nadgir, A.; Costa, K.; Schaletzky, J.; Yildiz, A.; Nguyenla, X.; Stanley, S.

10.1101/2020.09.14.295824 — biophysics — Posted on 2021-03-29

495 Differential expression of single-cell RNA-seq data using Tweedie models

Mallick, H.; Chatterjee, S.; Chowdhury, S.; Chatterjee, S.; Rahnavard, A.; Hicks, S. C.

10.1101/2021.03.28.437378 — bioinformatics — Posted on 2021-03-29

496 Human -Synuclein Inhibits Platelets Aggregation in vitro by Interfering with the -Thrombin/Protease-Activated Receptor 1 Functional Axis

Pontarollo, G.; Acquasaliente, L.; Radu, C. M.; Peterle, D.; Artusi, I.; Pagotto, A.; Uliana, F.; Simioni, P.; Negro, A.; De Filippis, V.

10.1101/2021.03.28.437436 — biochemistry — Posted on 2021-03-29

497 Whole genome duplications and the diversification of the Globin-X genes of vertebrates

Hoffmann, F.; Storz, J.; Kuraku, S.; Vandewege, M.; Opazo, J. C.

10.1101/2021.03.28.437409 — evolutionary biology — Posted on 2021-03-29

498 Deep learning for early warning signals of regime shifts

Bury, T.; Sujith, R.; Pavithran, I.; Scheffer, M.; Lenton, T.; Anand, M.; Bauch, C.

10.1101/2021.03.28.437429 — ecology — Posted on 2021-03-29

499 Mismatch between bird species sensitivity and the protection of intact habitats across the Americas

Cazalis, V.; Barnes, M. D.; Johnston, A.; Watson, J. E. M.; Sekercioglu, C. H.; Rodrigues, A. S. L.

10.1101/2021.03.28.437197 — ecology — Posted on 2021-03-29

500 H2S Prodrug, SG-1002, Protects Against Myocardial Oxidative Damage and Hypertrophy via Induction of Cystathionine beta-Synthase and Antioxidant Proteins

Islam, R. K.; Donnelly, E.; Hossain, F.; Gardner, J. D.; islam, k. N.

10.1101/2021.03.28.437435 — cell biology — Posted on 2021-03-29

501 Pulse labeling reveals the tail end of protein folding by proteome profiling

Zhu, M.; Kuechler, E. R.; Stoynov, N.; Gsponer, J.; Mayor, T.

10.1101/2021.03.28.437442 — cell biology — Posted on 2021-03-29

502 Strain diversity of plant-associated Lactiplantibacillus plantarum

Yu, A. O.; Goldman, E. A.; Brooks, J. T.; Golomb, B. A.; Yim, I. S.; Gotcheva, V.; Angelov, A.; Kim, E. B.; Marco, M. L.

10.1101/2021.03.28.437403 — microbiology — Posted on 2021-03-29

503 Laboratory mice with a wild microbiota generate strong allergic immune responses

Ma, J.; Classon, C. H.; Stark, J. M.; Li, M.; Huang, H.-J.; Vrtala, S.; Rosshart, S. P.; Nylen, S.; Coquet, J. M.

10.1101/2021.03.28.437143 — immunology — Posted on 2021-03-29

504 Endocervical regulatory T cells are associated with decreased genital inflammation and lower HIV target cell abundance

Ssemaganda, A.; Cholette, F.; Perner, M.; Kambaran, C.; Adhiambo, W.; Wambugu, P. M.; Gebrebrhan, H.; Lee, A.; Nuhu, F.; Mwatelah, R. S.; Jahan, N.; Omole, T. E.; Wanjiru, T.; Gitau, A.; Kimani, J.; McKinnon, L. R.

10.1101/2021.03.28.437432 — immunology — Posted on 2021-03-29

505 The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferons by engaging cytosolic DNA sensing in macrophages

Vail, K. J.; Petri da Silveira, B.; Bell, S. L.; Bordin, A. I.; Cohen, N. D.; Patrick, K. L.; Watson, R. O.

10.1101/2021.03.28.437424 — immunology — Posted on 2021-03-29

506 Delayed dosing of minocycline plus N-acetylcysteine reduces neurodegeneration in distal brain regions and restores spatial memory after experimental traumatic brain injury

Whitney, K.; Nikulina, E.; Rahman, S. N.; Alexis, A.; Bergold, P. J.

10.1101/2021.03.28.437090 — neuroscience — Posted on 2021-03-29

507 Imipramine and olanzapine block apoE4-catalyzed polymerization of Aβ and show evidence of improving Alzheimer's disease cognition

Johnson, N.; Wang, A. C.- J.; Coughlan, C.; Sillau, S.; Lucero, E.; Viltz, L.; Markham, N.; Allen, C.; Dhanasekaran, A. R.; Chial, H. J.; Potter, H.

10.1101/2021.03.28.437389 — neuroscience — Posted on 2021-03-29

508 Unravelling the shared genetic mechanisms underlying 18 autoimmune diseases using a systems approach

Gokuladhas, S.; Schierding, W.; Golovina, E.; Fadason, T.; O'Sullivan, J. M.

10.1101/2021.03.28.437437 — systems biology — Posted on 2021-03-29

509 Combining evolutionary and assay-labelled data for protein fitness prediction

Hsu, C.; Nisonoff, H.; Fannjiang, C.; Listgarten, J.

10.1101/2021.03.28.437402 — synthetic biology — Posted on 2021-03-29

510 TOR represses stress responses through global regulation of H3K27 trimethylation in plants

Dong, Y.; Uslu, V. V.; Berr, A.; Singh, G.; Papdi, C.; Steffens, V. A.; HEITZ, T.; Ryabova, L.

10.1101/2021.03.28.437410 — plant biology — Posted on 2021-03-29

511 Extended-Ensemble Docking to Probe Evolution of Ligand Binding Sites in Proteins Undergoing Large-Scale Structural Changes for Their Function

Kapoor, K.; Thangapandian, S.; Tajkhorshid, E.

10.1101/2021.03.28.437371 — biophysics — Posted on 2021-03-29

512 Exploring the structure and mechanics of thin supported inverse bicontinuous cubic phase lipid films

Ridolfi, A.; Humphreys, B.; Caselli, L.; Montis, C.; Nylander, T.; Berti, D.; Brucale, M.; Valle, F.

10.1101/2021.03.29.437497 — biophysics — Posted on 2021-03-29

513 The Ensembl COVID-19 resource: Ongoing integration of public SARS-CoV-2 data

De Silva, N. H.; Bhai, J.; Chakiachvili, M.; Contreras-Moreira, B.; Cummins, C.; Frankish, A.; Gall, A.; Genez, T.; Howe, K. L.; Hunt, S. E.; Martin, F. J.; Moore, B.; Ogeh, D.; Parker, A.; Parton, A.; Ruffier, M.; Pandian Sakthivel, M.; Sheppard, D.; Tate, J.; Thormann, A.; Thybert, D.; Trevanion, S. J.; Winterbottom, A.; Zerbino, D. R.; Finn, R. D.; Flicek, P.; Yates, A. D.

10.1101/2020.12.18.422865 — bioinformatics — Posted on 2021-03-29

514 MQuad enables clonal substructure discovery using single cell mitochondrial variants

Huang, Y.; Ho, J. W. K.; Kwok, A. W. C.; Qiao, C.; Huang, R.; Sham, M. H.

10.1101/2021.03.27.437331 — bioinformatics — Posted on 2021-03-29

515 GenTB: A user-friendly genome-based predictor for tuberculosis resistance powered by machine learning

Groschel, M. I.; Owens, M.; Freschi, L.; Vargas, R.; Marin, M. G.; Phelan, J.; Iqbal, Z.; Dixit, A.; Farhat, M. R.

10.1101/2021.03.27.437319 — bioinformatics — Posted on 2021-03-29

516 Small RNA-sequencing for Analysis of Circulating miRNAs: Benchmark Study

Androvic, P.; Benesova, S.; Rohlova, E.; Kubista, M.; Valihrach, L.

10.1101/2021.03.27.437345 — genomics — Posted on 2021-03-29

517 Large-scale phylogenomics of the genus Macrostomum (Platyhelminthes) reveals cryptic diversity and novel sexual traits

Brand, J.; Viktorin, G.; Wiberg, R. A. W.; Beisel, C.; Schaerer, L.

10.1101/2021.03.28.437366 — evolutionary biology — Posted on 2021-03-29

518 Epigenomic and transcriptomic differences between low-grade and acute inflammation in LPS-induced murine immune cells

Naler, L. B.; Hsieh, Y.-P.; Geng, S.; Zhou, Z.; Li, L.; Lu, C.

10.1101/2021.03.28.437377 — immunology — Posted on 2021-03-29

519 Single-cell characterisation of mononuclear phagocytes in the human intestinal mucosa

Fenton, T. M.; Wulff, L.; Jones, G.-R.; Vandamme, J.; Jorgensen, P. B.; Bain, C. C.; Lee, J.; Izarzugaza, J. M.; Belling, K. G.; Ho, G.-t.; Nielsen, O. H.; Riis, L. B.; Pers, T. H.; Jacobsen, H. L.; Mowat, A. M.; Brunak, S.; Agace, W. W.

10.1101/2021.03.28.437379 — immunology — Posted on 2021-03-29

520 A fluorescent nanosensor paint reveals the heterogeneity of dopamine release from neurons at individual release sites

Elizarova, S.; Chouaib, A.; Shaib, A.; Mann, F.; Brose, N.; Kruss, S.; Daniel, J. A.

10.1101/2021.03.28.437019 — neuroscience — Posted on 2021-03-29

521 The effects of emotional valence and intensity on cognitive and affective empathy after insula lesions

Holtmann, O.; Franz, M.; Moenig, C.; Tenberge, J.-G.; Preul, C.; Schwindt, W.; Bruchmann, M.; Melzer, N.; Miltner, W.; Straube, T.

10.1101/2021.03.28.436842 — neuroscience — Posted on 2021-03-29

522 The strange role of brain lesion size in cognitive neuropsychology

Sperber, C.

10.1101/2021.03.27.437336 — neuroscience — Posted on 2021-03-29

523 The Effect of Attention Load on Balance Control Performance

Mirloo, S.; Parpanchi, B.; Baghdadi, G.

10.1101/2021.03.28.437397 — neuroscience — Posted on 2021-03-29

524 Perceiving and remembering speech depend on nonlinearity in movements producing and exploring speech

Bloomfield, L.; Lane, E.; Mangalam, M.; Kelty-Stephen, D.

10.1101/2021.03.28.437328 — neuroscience — Posted on 2021-03-29

525 Functional expression of the ATP-gated P2X7 receptor in human iPSC-derived neurons and astrocytes

Kesavan, J.; Watters, O.; Dinkel, K.; Hamacher, M.; Prehn, J. H. M.; Henshall, D.; Engel, T.

10.1101/2021.03.28.437391 — neuroscience — Posted on 2021-03-29

526 Mathematical Model for the Study of Mitochondrial Retrograde Signaling Dynamics

Chiu, S.-T.; Tseng, W.-W.; Wei, A.-C.

10.1101/2021.03.27.437239 — systems biology — Posted on 2021-03-29

527 A dynamical model of TGF-β activation in asthmatic airways

Pybus, H. J.; O'Dea, R. D.; Brook, B. S.

10.1101/2021.03.28.437380 — systems biology — Posted on 2021-03-29

528 Tissue-specific mRNA profiling of the Brassica napus-Sclerotinia sclerotiorum interaction uncovers novel regulators of plant immunity

Walker, P.; Girard, I.; Giesbrecht, S.; Whyard, S.; Fernando, D.; de Kievit, T.; Belmonte, M. F.

10.1101/2021.03.27.437327 — plant biology — Posted on 2021-03-29

529 Pathogenesis-related protein 1 (PR-1) genes in soybean: genome-wide identification, structural analysis and expression profiling under multiple biotic and abiotic stresses

Almeida-Silva, F.; Venancio, T. M.

10.1101/2021.03.27.437342 — plant biology — Posted on 2021-03-29

530 Revisiting Decompression Sickness Risk and Mobility in the Context of the SmartSuit, a Hybrid Planetary Spacesuit

Kluis, L.; Diaz-Artiles, A.

10.1101/2021.03.26.437246 — physiology — Posted on 2021-03-29

531 An EMG-assisted Muscle-Force Driven Finite Element Analysis Pipeline to Investigate Joint- and Tissue-Level Mechanical Responses in Functional Activities: Towards a Rapid Assessment Toolbox

Esrafilian, A.; Stenroth, L.; Mononen, M. E.; Vartiainen, P.; Tanska, P.; Karjalainen, P. A.; Suomalainen, J.-S.; Arokoski, J.; Lloyd, D. G.; Korhonen, R. K.

10.1101/2021.03.27.436509 — biophysics — Posted on 2021-03-29

532 Anatomy of unfolding: The site-specific fold stability of Yfh1 measured by 2D NMR

Puglisi, R.; Karunanithy, G.; Hansen, D. F.; Pastore, A.; Temussi, P. A.

10.1101/2021.03.27.437329 — biophysics — Posted on 2021-03-29

533 CNAHap: a germline haplotyping method using tumor allele-specific copy number alteration

Tan, B.; Chen, L.; Jia, W.; Wang, Y.; Li, H.; Li, S.

10.1101/2021.03.27.437314 — bioinformatics — Posted on 2021-03-29

534 Bioinformatics analysis of potential key genes and mechanisms in type 2 diabetes mellitus

Vastrad, B. M.; Vastrad, C. M.

10.1101/2021.03.28.437386 — bioinformatics — Posted on 2021-03-29

535 Comprehensive machine-learning-based analysis of microRNA-target interactions reveals variable transferability of interaction rules across species

Ben Or, G.; Veksler-Lublinsky, I.

10.1101/2021.03.28.437385 — bioinformatics — Posted on 2021-03-29

536 A machine-learning algorithm correctly classifies cortical evoked potentials from both natural retinal stimulation and electrical stimulation of the optic nerve

Gaillet, V.; Borda, E.; Zollinger, E. G.; Ghezzi, D.

10.1101/2021.03.27.437330 — bioengineering — Posted on 2021-03-29

537 A NOVEL PARADIGM FOR DEEP REINFORCEMENT LEARNING OF BIOMIMETIC SYSTEMS

Sesha Iyengar, R.; Mallampalli, K.; Raghavan, M.

10.1101/2021.03.28.437396 — bioengineering — Posted on 2021-03-29

538 Electron transfer parameters for Methemoglobin formation in mutant Hemoglobin α-chains.

Dixit, V. A.; Blumberger, J.; Vyas, S. K.

10.1101/2021.03.28.437393 — biochemistry — Posted on 2021-03-29

539 Stand-alone lipoylated H-protein of the glycine cleavage system enables glycine cleavage and the synthesis of glycine from one-carbon compounds in vitro

Xu, Y.; Li, Y.; Zhang, H.; Nie, J.; Ren, J.; Wang, W.; Zeng, A.-p.

10.1101/2021.03.28.437365 — biochemistry — Posted on 2021-03-29

540 Time-course RNASeq of Camponotus floridanus forager and nurse ant brains indicate links between plasticity in the biological clock and behavioral division of labor

Das, B.; de Bekker, C.

10.1101/2021.03.27.433505 — animal behavior and cognition — Posted on 2021-03-29

541 Machine learning algorithms in big data analyses identify determinants of insulin gene transcription

Wong, W. K.; Thorat, V.; Joglekar, M. V.; Dong, C. X.; Lee, H.; Bhave, A.; Engin, F.; Pant, A.; Dalgaard, L. T.; Bapat, S.; Hardikar, A. A.

10.1101/2021.03.27.437353 — genetics — Posted on 2021-03-29

542 Desiccation stress acts as cause as well as cost of dispersal in Drosophila melanogaster

Mishra, A.; Tung, S.; Shree Sruti, V. R.; Shreenidhi, P. M.; Dey, S.

10.1101/2021.03.27.437318 — ecology — Posted on 2021-03-29

543 Identifying key federal, state, and private lands strategies for achieving 30x30 in the US

Dreiss, L.; Malcom, J. W.

10.1101/2021.03.26.437234 — ecology — Posted on 2021-03-29

544 Tolerance of Wildlife in Protected Area Borderlands

Merz, L.; Pienaar, E. F.; Fik, T.; Muyengwa, S.

10.1101/2021.03.27.436188 — ecology — Posted on 2021-03-29

545 Transcriptome profiling of embryonic retinal pigment epithelium reprogramming

Tangeman, J. A.; Luz-Madrigal, A.; Sreeskandarajan, S.; Grajales-Esquivel, E.; Liu, L.; Liang, C.; Tsonis, P. A.; Del Rio-Tsonis, K.

10.1101/2021.03.28.437384 — developmental biology — Posted on 2021-03-29

546 Generation and first characterization of TRDC-Knockout pigs lacking γδ T cells

Petersen, B.; Kammerer, R.; Frenzel, A.; Hassel, P.; Dau, T. H.; Becker, R.; Breithaupt, A.; Ulrich, R.; Lucas-Hahn, A.; Meyers, G.

10.1101/2021.03.27.437312 — immunology — Posted on 2021-03-29

547 A FOXN1 mutation competitively displaces wild-type FOXN1 from higher order nuclear condensates to cause immunodeficiency

Rota, I. A.; Handel, A. E.; Klein, F.; Maio, S.; Dhalla, F.; Deadman, M. E.; Cheuk, S.; Newman, J. A.; Michaels, Y. S.; Zuklys, S.; Prevot, N.; Hublitz, P.; Charles, P. D.; Gkazi, A. S.; Adamopoulou, E.; Qasim, W.; Davies, E. G.; Hanson, C.; Pagnamenta, A. T.; Camps, C.; Dreau, H. M.; White, A.; James, K.; Fischer, R.; Gileadi, O.; Taylor, J. C.; Fulga, T.; Lagerholm, B. C.; Anderson, G.; Sezgin, E.; Hollander, G. A.

10.1101/2021.03.28.437237 — immunology — Posted on 2021-03-29

548 Fast and accurate annotation of acoustic signals with deep neural networks

Steinfath, E.; Palacios, A.; Rottschaefer, J.; Yuezak, D.; Clemens, J.

10.1101/2021.03.26.436927 — neuroscience — Posted on 2021-03-29

549 Lumican regulates cervical corticospinal axon collateralization via non-autonomous crosstalk between distinct corticospinal neuron subpopulations

Itoh, Y.; Sahni, V.; Shnider, S.; Macklis, J. D.

10.1101/2021.03.26.437104 — neuroscience — Posted on 2021-03-29

550 High Gamma and Beta Temporal Interference Stimulation in the Human Motor Cortex Improves Motor Functions

Ma, R.; Xia, X.; Zhang, W.; Lu, Z.; Wu, Q.; Cui, J.; Song, H.; Fan, C.; Chen, X.; Wei, J.; Ji, G.; Wang, K.; Wang, X.; Qiu, B.; Zhang, X.

10.1101/2021.03.26.437107 — neuroscience — Posted on 2021-03-29

551 Adolescent ethanol exposure decreases cholinergic markers, blunts behaviorally-evoked acetylcholine and increases in apical dendritic branching within the orbital frontal cortex.

Kipp, B. T.; Nunes, P. T.; Galaj, E.; Hitchcock, B.; Nasra, T.; Poynor, K. R.; Heide, S. K.; Reitz, N. L.; Savage, L. M.

10.1101/2021.03.26.436863 — neuroscience — Posted on 2021-03-29

552 Coordinating With a Robot Partner Affects Action Monitoring Related Neural Processing

Czeszumski, A.; Gert, A. L.; Keshava, A.; Ghadirzadeh, A.; Kalthoff, T.; Ehinger, B. V.; Tiessen, M.; Björkman, M.; Kragic, D.; König, P.

10.1101/2021.03.26.437133 — neuroscience — Posted on 2021-03-29

553 Subthalamic-Cortical Network Reorganization during Parkinson's Tremor

Lauro, P.; Lee, S.; Asaad, W.

10.1101/2021.03.26.437170 — neuroscience — Posted on 2021-03-29

554 Stimulus presentation can enhance spiking irregularity across subcortical and cortical regions

Fayyaz, S.; Fakharian, M.; Ghazizadeh, A.

10.1101/2021.03.27.437321 — neuroscience — Posted on 2021-03-29

555 A projectome of the bumblebee central complex

Sayre, M. E.; Templin, R. M.; Chavez, J.; Kempenaers, J.; Heinze, S.

10.1101/2021.03.26.437137 — neuroscience — Posted on 2021-03-29

556 Functional dynamics of brain networks associated with carry-over effects of negative events on subsequent resting state.

Gaviria, J.; Rey, G.; Bolton, T.; Van De Ville, D.; Vuilleumier, P.

10.1101/2021.03.26.437275 — neuroscience — Posted on 2021-03-29

557 Neonatal 6-OHDA lesion of the SNc induces striatal compensatory sprouting from surviving SNc dopaminergic neurons without VTA contribution

Tanguay, W.; Ducrot, C.; Giguere, N.; Bourque, M.-J.; Trudeau, L.-E.

10.1101/2021.03.26.437271 — neuroscience — Posted on 2021-03-29

558 Resting-state based prediction of task-related activation in patients with disorders of consciousness

Craig, M. M.; Pappas, I.; Allanson, J.; Finoia, P.; Williams, G.; Pickard, J. D.; Menon, D.; Stamatakis, E.

10.1101/2021.03.27.436534 — neuroscience — Posted on 2021-03-29

559 The link between static and dynamic brain functional network connectivity and genetic risk of Alzheimer's disease

Sendi, M. S. E.; Zendehrouh, E.; Ellis, C. A.; Chen, J.; Miller, R. L.; Mormino, E. C.; Salat, D. H.; Calhoun, V.

10.1101/2021.03.27.437354 — neuroscience — Posted on 2021-03-29

560 Paternal obesity results in placental hypoxia and sex-specific impairments in placental vascularization and offspring metabolic function

Jazwiec, P. A.; Patterson, V. S.; Ribeiro, T. A.; Yeo, E.; Kennedy, K. M.; Mathias, P. C. F.; Petrik, J. J.; Sloboda, D. M.

10.1101/2021.03.27.437284 — physiology — Posted on 2021-03-29

561 Comparative in vitro antioxidant and antibacterial activities of leaf extract fractions of Crimson bottlebrush, Callistemon citrinus (Curtis.) Skeels

Ghosh, P.; Goswami, S.; Roy, S.; Das, R.; Chakraborty, T. C.; Ray, S.

10.1101/2021.03.26.436274 — pharmacology and toxicology — Posted on 2021-03-29

562 RENANO: a REference-based compressor for NANOpore FASTQ files

Dufort y Alvarez, G.; Seroussi, G.; Smircich, P.; Sotelo, J. R.; Ochoa, I.; Martin, A.

10.1101/2021.03.26.437155 — bioinformatics — Posted on 2021-03-29

563 SBGNview: Data Analysis, Integration and Visualization on All Pathways

Dong, X.; Vegesna, K.; Brouwer, C.; Luo, W.

10.1101/2021.03.26.437200 — bioinformatics — Posted on 2021-03-29

564 Interfacing Seurat with the R tidy universe

Mangiola, S.

10.1101/2021.03.26.437294 — bioinformatics — Posted on 2021-03-29

565 Discovery of signatures of fatal neonatal illness in vital signs using highly comparative time-series analysis

Niestroy, J.; Levinson, M. A.; Al Manir, S.; Clark, T. W.; Moorman, J. R.; Fairchild, K. D.; Lake, D. E.

10.1101/2021.03.26.437138 — bioinformatics — Posted on 2021-03-29

566 Little evidence that Eurasian jays (Garrulus glandarius) protect their caches by responding to cues about a conspecific's desire and visual perspective

Amodio, P.; Farrar, B. G.; Krupenye, C.; Ostojic, L.; Clayton, N. S.

10.1101/2021.03.26.437226 — animal behavior and cognition — Posted on 2021-03-29

567 MLG: Multilayer graph clustering for multi-condition scRNA-seq data

Lu, S.; Conn, D. J.; Chen, S.; Johnson, K. D.; Bresnick, E. H.; Keles, S.

10.1101/2021.03.26.437231 — genomics — Posted on 2021-03-29

568 iTaxoTools 0.1: Kickstarting a specimen-based software toolkit for taxonomists

Vences, M.; Miralles, A.; Brouillet, S.; Ducasse, J.; Fedosov, A.; Kharchev, V.; Kostadinov, I.; Kumari, S.; Patmanidis, S.; Scherz, M. D.; Puillandre, N.; Renner, S. S.

10.1101/2021.03.26.435825 — evolutionary biology — Posted on 2021-03-29

569 Data-driven speciation tree prior for better species divergence times in calibration-poor molecular phylogenies

Tao, Q.; Barba-Montoya, J.; Kumar, S.

10.1101/2021.03.27.437326 — evolutionary biology — Posted on 2021-03-29

570 Tactile spatial discrimination on the torso using vibrotactile and force stimulation

Fadaei Jouybari, A.; Franza, M.; Kannape, O. A.; Hara, M.; Blanke, O.

10.1101/2021.03.26.437195 — neuroscience — Posted on 2021-03-29

571 Identification of Blood Based biomarker for Huntington's disease using in-silico gene expression analysis

Chakraborty, S.

10.1101/2021.03.26.437248 — neuroscience — Posted on 2021-03-29

572 Acute vagus nerve stimulation does not affect liking or wanting ratings of food in healthy participants

Müller, F. K.; Teckentrup, V.; Kühnel, A.; Ferstl, M.; Kroemer, N. B.

10.1101/2021.03.26.437062 — neuroscience — Posted on 2021-03-29

573 Association of stress-related limbic activity and baseline interleukin-6 plasma levels in healthy adults

Voges, J. F.; Mueller-Pinzler, L.; Neis, M.; Luebber, F.; Lange, T.; Hundt, J. E.; Kasten, M.; Kraemer, U. M.; Krach, S.; Rademacher, L.

10.1101/2021.03.26.437134 — neuroscience — Posted on 2021-03-29

574 Histologic and Proteomic Remodeling of the Pulmonary Veins and Arteries in a Porcine Model of Chronic Pulmonary Venous Hypertension

Fayyaz, A. U.; Sabbah, M. S.; Dasari, S.; Griffiths, L. G.; DeBrock, H. M.; Charlesworth, M. C.; Borlaug, B. A.; Jenkins, S. M.; Edwards, W. D.; Redfield, M. M.

10.1101/2021.03.26.437051 — physiology — Posted on 2021-03-29

575 Tracking the contribution of inductive bias to individualized internal models

Török, B.; Nagy, D. G.; Kiss, M. M.; Janacsek, K.; Nemeth, D.; Orban, G.

10.1101/2020.06.22.163295 — neuroscience — Posted on 2021-03-29

576 Deep Learning Improves Macromolecule Identification in 3D Cellular Cryo-Electron Tomograms

Moebel, E.; Martinez-Sanchez, A.; Lamm, L.; Righetto, R.; Wietrzynski, W.; Albert, S.; Lariviere, D.; Fourmentin, E.; Pfeffer, S.; Ortiz, J.; Baumeister, W.; Peng, T.; Engel, B. D.; Kervrann, C.

10.1101/2020.04.15.042747 — bioinformatics — Posted on 2021-03-29

577 A deep learning framework for real-time detection of novel pathogens during sequencing

Bartoszewicz, J. M.; Genske, U.; Renard, B. Y.

10.1101/2021.01.26.428301 — bioinformatics — Posted on 2021-03-29

578 BLight: Efficient exact associative structure for k-mers

Marchet, C.; Kerbiriou, M.; Limasset, A.

10.1101/546309 — bioinformatics — Posted on 2021-03-29

579 Strong effect of Penicillium roqueforti populations on volatile and metabolic compounds responsible for aromas, flavor and texture in blue cheeses

Caron, T.; Le Piver, M.; Peron, A.-C.; Lieben, P.; Lavigne, R.; Brunel, S.; Roueyre, D.; Place, M.; Bonnarme, P.; Giraud, T.; Branca, A.; Landaud, S.; Chassard, C.

10.1101/2020.03.02.974352 — evolutionary biology — Posted on 2021-03-29

580 Is a Ring-arranged Vascular Pattern Unique to Stems? A Three Dimensional Reconstruction of Anaxagorea (Annonaceae) Carpel Vasculature and its Evolutionary Implications

Li, Y.; Du, W.; Chen, Y.; Wang, S.; Wang, X.-F.

10.1101/2020.05.22.111716 — evolutionary biology — Posted on 2021-03-29

581 Late-life fitness gains explain the absence of a selection shadow in ants

Jaimes Nino, L. M.; Heinze, J.; Oettler, J.

10.1101/2021.02.24.432699 — evolutionary biology — Posted on 2021-03-29

582 Human iPSC-derived renal cells change their immunogenic properties during maturation: Implications for regenerative therapies

Rossbach, B.; Hariharan, K.; Mah, N.; Oh, S. J.; Volk, H.-D.; Reinke, P.; Kurtz, A.

10.1101/2021.03.01.432225 — cell biology — Posted on 2021-03-29

583 Microbial helpers allow cyanobacteria to thrive in ferruginous waters

Szeinbaum, N.; Toporek, Y. J.; Reinhard, C. T.; Glass, J. B.

10.1101/2020.05.08.085001 — microbiology — Posted on 2021-03-29

584 Characterising sensorimotor adaptation in Complex Regional Pain Syndrome

Vitterso, A. D.; Buckingham, G.; Ten Brink, A. F.; Halicka, M.; Proulx, M. J.; Bultitude, J. H.

10.1101/841205 — neuroscience — Posted on 2021-03-29

585 Comparative multi-tissue profiling reveals extensive tissue-specificity in transcriptome reprogramming upon cold exposure

Trajkovski, M.; Hadadi, N.; Steinbach, K.; Salinas, G.; Merkler, D.; Spiljar, M.

10.1101/2021.03.26.437139 — physiology — Posted on 2021-03-29

586 Analysis of single-cell RNA sequencing data basedon autoencoders

Tangherloni, A.; Ricciuti, F.; Besozzi, D.; Lio, P.; Cvejic, A.

10.1101/727867 — bioinformatics — Posted on 2021-03-29

587 ISA API: An open platform for interoperable life science experimental metadata

Johnson, D.; Cochrane, K.; Davey, R. P.; Etuk, A.; Gonzalez-Beltran, A.; Haug, K.; Izzo, M.; Larralde, M.; Lawson, T. N.; Minotto, A.; Moreno, P.; Nainala, V. C.; O'Donovan, C.; Pireddu, L.; Roger, P.; Shaw, F.; Steinbeck, C.; Weber, R. J.; Sansone, S.-A.; Rocca-Serra, P.

10.1101/2020.11.13.382119 — bioinformatics — Posted on 2021-03-29

588 How robust are cross-population signatures of polygenic adaptation in humans?

Refoyo-Martinez, A.; Liu, S.; Jorgensen, A. M.; Jin, X.; Albrechtsen, A.; Martin, A. R.; Racimo, F.

10.1101/2020.07.13.200030 — evolutionary biology — Posted on 2021-03-29

589 A digitization theory of the Weber-Fechner law

Choe, H.

10.1101/2021.03.15.435555 — neuroscience — Posted on 2021-03-29

590 Brain-wide neuronal activation and functional connectivity are modulated by prior exposure to repetitive learning episodes.

Terstege, D. J.; Durante, I. M.; Epp, J. R.

10.1101/2021.03.28.437394 — neuroscience — Posted on 2021-03-29

591 Robustness of individualized inferences from longitudinal resting state dynamics

Hommelsen, M.; Viswanathan, S.; Daun, S.

10.1101/2020.09.15.297572 — neuroscience — Posted on 2021-03-29

592 Effects of short-term isolation on social animals' behavior: an experimental case study of Japanese macaque

Morita, T.; Toyoda, A.; Aisu, S.; Suda-Hashimoto, N.; Kaneko, A.; Adachi, I.; Matsuda, I.; Koda, H.

10.1101/2021.03.28.437096 — animal behavior and cognition — Posted on 2021-03-29

593 Is a Ring-arranged Vascular Pattern Unique to Stems? A Three Dimensional Reconstruction of Anaxagorea (Annonaceae) Carpel Vasculature and its Evolutionary Implications

Li, Y.; Du, W.; Chen, Y.; Wang, S.; Wang, X.-F.

10.1101/2020.05.22.111716 — evolutionary biology — Posted on 2021-03-29

594 Length-length and length-weight relationships for four small pelagic fishes in the Kuroshio-Oyashio current system

Furuichi, S.; Kamimura, Y.; Yukami, R.

10.1101/2020.12.16.423010 — ecology — Posted on 2021-03-29

595 Transcription initiation at a consensus bacterial promoter proceeds via a "bind-unwind-load-and-lock" mechanism

Mazumder, A.; Ebright, R. H.; Kapanidis, A.

10.1101/2021.03.28.437135 — biochemistry — Posted on 2021-03-28

596 Energy Landscape of Ubiquitin is Weakly Multidimensional

Mondal, B.; Thirumalai, D.; Reddy, G.

10.1101/2021.03.28.437368 — biophysics — Posted on 2021-03-28

597 Effects of sequence motifs in the yeast 3' untranslated region determined from massively-parallel assays of random sequences

Savinov, A.; Brandsen, B. M.; Angell, B. E.; Cuperus, J. T.; Fields, S.

10.1101/2021.03.27.437361 — genomics — Posted on 2021-03-28

598 Ecological correlates of gene family size in a pine-feeding sawfly genome and across Hymenoptera

Vertacnik, K.; Herrig, D.; Godfrey, R. K.; Hill, T.; Geib, S.; Unckless, R.; Nelson, D.; Linnen, C. R.

10.1101/2021.03.14.435331 — evolutionary biology — Posted on 2021-03-28

599 Optimal coordination and reorganization of photosynthetic properties in C4 grasses

Zhou, H.; Akcay, E.; Helliker, B.

10.1101/2020.05.15.098327 — ecology — Posted on 2021-03-28

600 The legacy of C4 evolution in the hydraulics of C3 and C4 grasses

Zhou, H.; Akcay, E.; Edwards, E.; Helliker, B.

10.1101/2020.05.14.097030 — ecology — Posted on 2021-03-28

601 Integrative Transcriptomic Analysis Reveals the Immune Mechanism for A CyHV-3-Resistant Common Carp Strain

Jia, Z.; Wu, N.; Jiang, X.; Li, H.; Sun, J.; Shi, M.; Li, C.; Hu, X.; Ge, Y.; Ye, W.; Tang, Y.; Shan, J.; Cheng, Y.; Xia, X.-Q.; Shi, L.

10.1101/2020.11.10.375915 — immunology — Posted on 2021-03-28

602 GABA facilitates spike propagation at branch points of sensory axons in the spinal cord

Hari, K.; Lucas-Osma, A. M.; Metz, K.; Lin, S.; Pardell, N.; Roszko, D.; Black, S.; Minarik, A.; Singla, R.; Stephens, M. J.; Fouad, K.; Jones, K. E.; Gorassini, M. A.; Fenrich, K. K.; Li, Y.; Bennett, D. J.

10.1101/2021.01.20.427494 — neuroscience — Posted on 2021-03-28

603 Orthogonal neural codes for phonetic features in the infant brain

Gennari, G.; Marti, S.; Palu, M.; Flo, A.; Dehaene-Lambertz, G.

10.1101/2021.03.28.437156 — neuroscience — Posted on 2021-03-28

604 Measuring hidden phenotype: Quantifying the shape of barley seeds using the Euler Characteristic Transform

Amezquita, E. J.; Quigley, M. Y.; Ophelders, T.; Landis, J. B.; Koenig, D.; Munch, E.; Chitwood, D. H.

10.1101/2021.03.27.437348 — plant biology — Posted on 2021-03-28

605 Haplotype-aware pantranscriptome analyses using spliced pangenome graphs

Sibbesen, J. A.; Eizenga, J. M.; Novak, A. M.; Siren, J.; Chang, X.; Garrison, E.; Paten, B.

10.1101/2021.03.26.437240 — bioinformatics — Posted on 2021-03-28

606 Comparative analysis of the unbinding pathways of antiviral drug Indinavir from HIV and HTLV1 proteases by Supervised Molecular Dynamics simulation

Sohraby, F.; Aryapour, H.

10.1101/2021.03.27.437308 — bioinformatics — Posted on 2021-03-28

607 Correction for sample overlap, winner's curse and weak instrument bias in two-sample Mendelian Randomization

Mounier, N.; Kutalik, Z.

10.1101/2021.03.26.437168 — genetics — Posted on 2021-03-28

608 Temperature predicts the maximum tree-species richness and water and frost shape the residual variation

Segovia, R. A.

10.1101/836338 — ecology — Posted on 2021-03-28

609 Paraburkholderia edwinii protects Aspergillus sp. from phenazines by acting as a toxin sponge

Dahlstrom, K. M.; Newman, D. K.

10.1101/2021.03.28.437412 — microbiology — Posted on 2021-03-28

610 Axon guidance modalities in CNS regeneration revealed by quantitative proteomic analysis

Vilallongue, N.; Schaeffer, J.; Hesse, A.-M.; Delpech, C.; Paccard, A.; Coute, Y.; Belin, S.; Nawabi, H.

10.1101/2021.03.26.437129 — neuroscience — Posted on 2021-03-28

611 Involvement of denervated midbrain-derived factors in the formation of ectopic cortico-mesencephalicprojection after hemispherectomy

Chang, L.; Masada, M.; Kojima, M.; Yamamoto, N.

10.1101/2021.03.26.437124 — neuroscience — Posted on 2021-03-28

612 Global community effect: large-scale cooperation yields collective survival of differentiating embryonic stem cells

Daneshpour, H.; van den Bersselaar, P.; Youk, H.

10.1101/2020.12.20.423651 — systems biology — Posted on 2021-03-28

613 The temperature-regulated DEAD-box RNA helicase CrhR interactome: Autoregulation and photosynthesis-related transcripts

Migur, A.; Heyl, F.; Fuss, J.; Srikumar, A.; Huettel, B.; Steglich, C.; Prakash, J. S. S.; Reinhardt, R.; Backofen, R.; Owttrim, G. W.; Hess, W. R.

10.1101/2021.03.26.437152 — plant biology — Posted on 2021-03-28

614 The phosphate starvation response recruits the TOR pathway to regulate growth in Arabidopsis cell cultures

Dobrenel, T.; Kushwah, S.; Mubeen, U.; Jansen, W.; Delhomme, N.; Caldana, C.; Hanson, J.

10.1101/2021.03.26.437164 — plant biology — Posted on 2021-03-28

615 Uvariopsis ebo (Annonaceae) a new, Critically Endangered tree species from the Ebo Forest, Cameroon and a key to the Cameroonian species of Uvariopsis

Gosline, G.; Cheek, M.; Onana, J. M.; Ngansop, E.; van der Burgt, X.; Dagallier, L.-P.

10.1101/2021.03.26.437154 — plant biology — Posted on 2021-03-28

616 Gene Expression Variation in Arabidopsis Embryos at Single-Nucleus Resolution

Kao, P.; Schon, M. A.; Mosiolek, M.; Nodine, M. D.

10.1101/2021.03.26.437151 — plant biology — Posted on 2021-03-28

617 ModPhred: an integrative toolkit for the analysis and storage of nanopore sequencing DNA and RNA modification data

Pryszcz, L. P.; Novoa, E. M.

10.1101/2021.03.26.437220 — bioinformatics — Posted on 2021-03-28

618 Profiles of expressed mutations in single cells reveal patterns of tumor evolution and therapeutic impact of intratumor heterogeneity

Rashidi Mehrabadi, F.; Marie, K. L.; Perez-Guijarro, E.; Malikic, S.; Sadeqi Azer, E.; Yang, H. H.; Kizilkale, C.; Gruen, C.; Liu, H.; Kelly, M. C.; Marcelus, C.; Burkett, S.; Buluc, A.; Ergun, F.; Lee, M. P.; Merlino, G.; Day, C.-P.; Sahinalp, S. C.

10.1101/2021.03.26.437185 — bioinformatics — Posted on 2021-03-28

619 Building the Mega Single Cell Transcriptome Ocular Meta-Atlas

Swamy, V. S.; Fufa, T. D.; Hufnagel, R. B.; McGaughey, D. M.

10.1101/2021.03.26.437190 — bioinformatics — Posted on 2021-03-28

620 Continuous monitoring reveals protective effects of N-acetylcysteine amide on an isogenic microphysiological model of the neurovascular unit

Matthiesen, I.; Voulgaris, D.; Nikolakopoulou, P.; Winkler, T. E.; Herland, A.

10.1101/2021.03.26.433307 — bioengineering — Posted on 2021-03-28

621 Optimized hip-knee-ankle exoskeleton assistance at a range of walking speeds

Bryan, G. M.; Franks, P. W.; Song, S.; Voloshina, A. S.; Reyes, R.; O'Donovan, M. P.; Gregorczyk, K. N.; Collins, S. H.

10.1101/2021.03.26.437212 — bioengineering — Posted on 2021-03-28

622 Succinate is Broadly Tissue-Permeant and Uncouples Mitochondrial Respiration from ATP Synthesis

Hass, D. T.; Robbings, B. M.; Bisbach, C. M.; Giering, E.; Mundinger, T. O.; Sadilek, M.; Sweet, I. R.; Hurley, J. B.

10.1101/2021.02.10.430650 — biochemistry — Posted on 2021-03-28

623 Flow cytometry-based determination of ploidy from dried leaf specimens in genomically complex collections of the tropical forage grass Urochloa s. l.

Tomaszewska, P.; Pellny, T. K.; Hernandez, L. M.; Mitchell, R. A. C.; Castiblanco, V.; de Vega, J. J.; Schwarzacher, T.; Heslop-Harrison, P.

10.1101/2021.03.26.437252 — genomics — Posted on 2021-03-28

624 Sexual antagonism in haplodiploids

Hitchcock, T. J.; Gardner, A.; Ross, L.

10.1101/2021.03.26.437233 — evolutionary biology — Posted on 2021-03-28

625 A distinct expression profile in the cerebellum and striatum for genes under selection within introgression deserts

Buisan, R.; Moriano, J.; Andirko, A.; Boeckx, C.

10.1101/2021.03.26.437167 — evolutionary biology — Posted on 2021-03-28

626 Tracking the rates and mechanisms of canopy damage and recovery following Hurricane Maria using multitemporal lidar data

Leitold, V.; Morton, D. C.; Martinuzzi, S.; Paynter, I.; Uriarte, M.; Keller, M.; Ferraz, A.; Cook, B. D.; Corp, L. A.; Gonzalez, G.

10.1101/2021.03.26.436869 — ecology — Posted on 2021-03-28

627 Every cog and wheel: Unraveling biocomplexity at the genomic and phenotypic level in a population complex of Chinook salmon.

O'Leary, S. J.; Thompson, T. Q.; Meek, M. H.

10.1101/2021.03.26.437213 — ecology — Posted on 2021-03-28

628 A Chemical-Enhanced System for CRISPR-Based Nucleic Acid Detection

Li, Z.; Zhao, W.; Ma, S.; Li, Z.; Yao, Y.; Fei, T.

10.1101/2021.03.28.437376 — molecular biology — Posted on 2021-03-28

629 Epithelial GPR35 protects from Citrobacter rodentium infection by preserving goblet cells and mucosal barrier integrity

Melhem, H.; Kaya, B.; Kaymak, T.; Wuggenig, P.; Flint, E.; Roux, J.; Cavelti-Weder, C.; Balmer, M.; Walser, J.-C.; Morales, R.; Riedel, C.; Liberali, P.; Villablanca, E.; Niess, J.

10.1101/2021.03.27.437264 — immunology — Posted on 2021-03-28

630 mTORC2 contributes to murine lupus

Zhou, X.; Qi, H.; Li, Y.; Zhu, X.; Amin, S.; Mariam, A.; Diadhiou, C.; Davidson, A.; Zeng, H.

10.1101/2021.03.27.437347 — immunology — Posted on 2021-03-28

631 Continuity within somatosensory cortical map shapes the integration of optogenetic input

Lassagne, H.; Goueytes, D.; Shulz, D.; Estebanez, L.; Ego-Stengel, V.

10.1101/2021.03.26.437211 — neuroscience — Posted on 2021-03-28

632 Sensorimotor temporal recalibration: the contribution of motor-sensory and inter-sensory components

Arikan, B. E.; van Kemenade, B.; Fiehler, K.; Kircher, T.; Drewing, K.; Straube, B.

10.1101/2021.03.26.437189 — neuroscience — Posted on 2021-03-28

633 Rescue of aberrant huntingtin palmitoylation ameliorates mutant huntingtin-induced toxicity

Lemarie, F. L.; Caron, N. S.; Sanders, S. S.; Schmidt, M. E.; Nguyen, Y. T. N.; Ko, Y.; Xu, X.; Pouladi, M. A.; Martin, D. D. O.; Hayden, M. R.

10.1101/2021.03.26.437210 — neuroscience — Posted on 2021-03-28

634 Dynamic bi-directional phosphorylation events associated with the reciprocal regulation of synapses during homeostatic up- and down-scaling.

Desch, K.; Langer, J. D.; Schuman, E. M.

10.1101/2021.03.26.437166 — neuroscience — Posted on 2021-03-28

635 TPST-dependent and -independent regulation of root development and signaling by PSK LRR receptor kinases in Arabidopsis

Kaufmann, C.; Stührwohldt, N.; Sauter, M.

10.1101/2021.03.26.437140 — plant biology — Posted on 2021-03-28

636 An acylsugar-deficient Nicotiana benthamiana strain for aphid and whitefly research

Feng, H.; Acosta-Gamboa, L.; Kruse, L. H.; Tracey, J. D.; Chung, S. H.; Nava Fereira, A. R.; Shakir, S.; Xu, H.; Sunter, G.; Gore, M. A.; Casteel, C. L.; Moghe, G. D.; Jander, G.

10.1101/2020.08.04.237180 — plant biology — Posted on 2021-03-28

637 Silk-based antimicrobial peptide mixed with recombinant spidroin creates functionalized spider silk

Liu, F. Y. C.

10.1101/2021.03.26.437269 — bioengineering — Posted on 2021-03-28

638 Decoding Object Weight from Electromyography during Human Grasping

Lashgari, E.; Pouya, A.; Maoz, U.

10.1101/2021.03.26.437230 — bioengineering — Posted on 2021-03-28

639 Edge strand of Escherichia coli BepA interacts with immature LptD on the β-barrel assembly machine to direct it to on- and off-pathways

Miyazaki, R.; Watanabe, T.; Yoshitani, K.; Akiyama, Y.

10.1101/2021.03.28.437416 — biochemistry — Posted on 2021-03-28

640 Swimming kinematics and performance of spinal transected lampreys with different levels of axon regeneration

Fies, J.; Gemmell, B. J.; Fogerson, S. M.; Costello, J. H.; Morgan, J. R.; Tytell, E. D.; Colin, S. P.

10.1101/2021.03.26.437228 — animal behavior and cognition — Posted on 2021-03-28

641 Gene structure, differential exon usage, and expression of the testis long intergenic non-protein coding RNA 1016 in humans reveals isoform-specific roles in controlling biological processes

Ramos, E. I.; Yang, B.; Vasquez, Y. M.; Lin, K. Y.; Choudhari, R.; Gadad, S. S.

10.1101/2021.03.26.437262 — genomics — Posted on 2021-03-28

642 Species Tree Inference on Data with Paralogs is Accurate Using Methods Intended to Deal with Incomplete Lineage Sorting

Yan, Z.; Smith, M.; Du, P.; Hahn, M. W.; Nakhleh, L.

10.1101/498378 — evolutionary biology — Posted on 2021-03-28

643 Frequent origins of traumatic insemination involve convergent shifts in sperm and genital morphology

Brand, J. N.; Harmon, L.; Schaerer, L.

10.1101/2021.02.16.431427 — evolutionary biology — Posted on 2021-03-28

644 Accessory genomic epidemiology of co-circulating Acinetobacter baumannii clones

Mateo-Estrada, V.; Fernandez-Vazquez, J. L.; Moreno, J.; Hernandez-Gonzalez, I.; Rodriguez-Noriega, E.; Morfin-Otero, R.; Alcantar-Curiel, M. D.; Castillo-Ramirez, S.

10.1101/2021.03.26.436874 — microbiology — Posted on 2021-03-28

645 Single cell trajectory modeling identifies a primitive trophoblast state defined by BCAM enrichment

Shannon, M.; Baltayeva, J.; Castellana, B.; Wachter, J.; Yoon, S.; Treissman, J.; Le, H. T.; Beristain, A. G.

10.1101/2021.03.27.437349 — developmental biology — Posted on 2021-03-28

646 Single Cell, Single Nucleus and Spatial RNA Sequencing of the Human Liver Identifies Hepatic Stellate Cell and Cholangiocyte Heterogeneity

Andrews, T. S.; Atif, J.; Liu, J. C.; Perciani, C. T.; Ma, X.-Z.; Thoeni, C.; Slyper, M.; Eraslan, G.; Segerstolpe, A.; Manuel, J.; Chung, S.; Winter, E.; Cirlan, I.; Khuu, N.; Fischer, S.; Rozenblatt-Rosen, O.; Regev, A.; McGilvray, I. D.; Bader, G. D.; MacParland, S. A.

10.1101/2021.03.27.436882 — cell biology — Posted on 2021-03-28

647 Decoding regulatory specificity of human ribosomal proteins on global gene expression

Luan, Y.; Tang, N.; Yang, J.; Liu, S.; Cheng, C.; Wang, Y.; Guo, Y.; Wang, H.; Xiang, M.; Ju, R.; Xie, Z.

10.1101/2021.03.27.437302 — cell biology — Posted on 2021-03-28

648 Histone H3 dopaminylation in ventral tegmental area underlies heroin-induced maladaptive plasticity

Fulton, S. L.; Mitra, S.; Lepack, A. E.; Martin, J. A.; Dietz, D. M.; Maze, I.

10.1101/2021.03.26.437235 — neuroscience — Posted on 2021-03-28

649 Hugin+ neurons link the sleep homeostat to circadian clock neurons

Schwarz, J. E.; King, A. N.; Hsu, C. T.; Barber, A. F.; Sehgal, A.

10.1101/2020.04.29.068627 — neuroscience — Posted on 2021-03-28

650 Purkinje Cell Activity During Suppression of Voluntary Eye Movements in Rhesus Macaques

Avila, E.; Flierman, N.; Holland, P. J.; Roelfsema, P. R.; Frens, M. A.; Badura, A.; De Zeeuw, C. I.

10.1101/2021.03.26.437236 — neuroscience — Posted on 2021-03-28

651 Canagliflozin increases adenoma burden in female APCMin/+ mice

Korfhage, J. L.; Skinner, M. E.; Basu, J.; Greenson, J. K.; Miller, R. A.; Lombard, D. B.

10.1101/2021.03.27.437278 — cancer biology — Posted on 2021-03-28

652 Dynamic phase separation of the androgen receptor and its coactivators to regulate gene expression.

Zhang, F.; Wong, S.; Lee, J.; Lingadahalli, S.; Wells, C.; Saxena, N.; Sanchez, C.; Sun, B.; Parra-Nunez, A. K.; Chan, N.; Bui, J. M.; Wang, Y.; Rennie, P. S.; Lack, N. A.; Cherkasov, A.; Gleave, M. E.; Gsponer, J.; Lallous, N.

10.1101/2021.03.27.437301 — cancer biology — Posted on 2021-03-28

653 Consensus tandem tetratricopeptide repeat proteins are complex superhelical nanosprings

Synakewicz, M.; Eapen, R.; Perez-Riba, A.; Bauer, D.; Weissl, A.; Fischer, G.; Hyvonen, M.; Rief, M.; Itzhaki, L. S.; Stigler, J.

10.1101/2021.03.27.437344 — biophysics — Posted on 2021-03-28

654 High content 3D imaging method for quantitative characterization of organoid development and phenotype.

Beghin, A.; Grenci, G.; Rajendiran, H.; Delaire, T.; Raffi, S. B. M.; Blanc, D.; De Mets, R.; Ong, H. T.; Acharya, V.; Sahni, G.; Racine, V.; Galland, R.; Sibarita, J.-B.; Viasnoff, V.

10.1101/2021.03.26.437121 — biophysics — Posted on 2021-03-28

655 Single cell trajectory modeling identifies a primitive trophoblast state defined by BCAM enrichment

Shannon, M.; Baltayeva, J.; Castellana, B.; Wachter, J.; Yoon, S.; Treissman, J.; Le, H. T.; Beristain, A. G.

10.1101/2021.03.27.437349 — developmental biology — Posted on 2021-03-28

656 Regenerating vascular mural cells in zebrafish fin blood vessels are not derived from pre-existing ones and differentially require pdgfrb signaling for their development

Siekmann, A. F.; Leonard, E. V.; Figueroa, R.; Bussmann, J.; Amigo, J. D.; Lawson, N. D.

10.1101/2021.03.27.437334 — developmental biology — Posted on 2021-03-28

657 Paenibacillus sp. strain UY79, isolated from a root nodule of Arachis villosa, displays a broad spectrum of antifungal activity

Costa, A.; Corallo, B.; Amarelle, V.; Stewart, S.; Pan, D.; Tiscornia, S.; Fabiano, E. R.

10.1101/2021.03.26.437297 — microbiology — Posted on 2021-03-28

658 The metastable brain associated with autistic-like traits of typically developing individuals

Sase, T.; Kitajo, K.

10.1101/855502 — neuroscience — Posted on 2021-03-28

659 Comprehensive analysis of male-free reproduction in Monomorium triviale (Formicidae: Myrmicinae)

Idogawa, N.; Sasaki, T.; Tsuji, K.; Dobata, S.

10.1101/2021.01.26.428225 — zoology — Posted on 2021-03-28

660 Appraisal of Cell Cycle Delay and Cytotoxicity Inducing Potential of 3-epicaryoptin in Allium Cepa L.

Barman, M.; Ray, S.

10.1101/2021.03.26.437299 — pharmacology and toxicology — Posted on 2021-03-28

661 Identification and prediction of developmental enhancers in sea urchin embryos

Arenas-Mena, C.; Miljovska, S.; Ercan, S.; Shashikant, T.; Danko, C. G.; Rice, E. J.

10.1101/2021.03.26.436886 — genomics — Posted on 2021-03-28

662 Quantification of the evolutionary constraint on intronic branch point sequences in the bovine and human genome

Kadri, N. K.; Pausch, H.

10.1101/2021.03.26.437175 — genomics — Posted on 2021-03-28

663 Origins of cancer genome complexity revealed by haplotype-resolved genomic analysis of evolution of Barretts esophagus to esophageal adenocarcinoma

Zhang, C.-Z.; Stachler, M.; Bao, C.; Tourdot, R.; Brunette, G. J.; Stewart, C.; Sun, L.; Baba, H.; Watanabe, M.; Agoston, A.; Jajoo, K.; Nason, K.; Davison, J.; Getz, G.; Wang, K.; Imamura, Y.; Odze, R.; Bass, A.

10.1101/2021.03.26.437288 — genomics — Posted on 2021-03-28

664 Genomic analysis of response to neoadjuvant chemotherapy in esophageal adenocarcinoma

Izadi, F.; Sharpe, B. P.; Breininger, S. P.; Secrier, M.; Gibson, J.; Walker, R. C.; Rahman, S.; Devonshire, G.; Lloyd, M. A.; Walters, Z. S.; Fitzgerald, R. C.; Rose-Zerilli, M. J. J.; Underwood, T. J.; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium,

10.1101/2021.03.26.437144 — genomics — Posted on 2021-03-28

665 Draft Genome of the Korean smelt (Hypomesus nipponensis) and its transcriptomic responses to heat stress in the liver and muscle

Xuan, B.; Park, J.; Choi, S.; You, I.; Nam, B.-H.; Noh, E. S.; Kim, E. M.; Song, M.-Y.; Shin, Y.; Jeon, J.-H.; Kim, E. B.

10.1101/2021.03.26.437215 — genetics — Posted on 2021-03-28

666 Machine-learning prediction of resistance to sub-inhibitory antimicrobial concentrations from Escherichia coli genomes

Benkwitz-Bedford, S.; Palm, M.; Demirtas, T. Y.; Mustonen, V.; Farewell, A.; Warringer, J.; Moradigaravand, D.; Parts, L.

10.1101/2021.03.26.437296 — microbiology — Posted on 2021-03-28

667 Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling

Light, T. L.; Brun, D.; Guardado-Calvo, P.; Pederzoli, R.; Haouz, A.; Neipel, F.; Rey, F. A.; Hristova, K.; Backovic, M.

10.1101/2021.03.26.437132 — microbiology — Posted on 2021-03-28

668 Kenyan Traditional Medicine: Exploring Old Solutions to the Modern Antibacterial Crises Through Natural Products Chemistry

Ndegwa, F. K.; Kondam, C.; Ghose, D.; Esan, T. E.; Waxali, Z. S.; Miller, M. E.; Meganathan, R.; Gikonyo, N. K.; Mbugua, P. K.; Okemo, P. O.; Hagen, T. J.

10.1101/2021.03.26.436821 — microbiology — Posted on 2021-03-28

669 Parental-fetal interplay of immune genes leads to intrauterine growth restriction

Kaur, G.; Porter, C. B. M.; Ashenberg, O.; Lee, J.; Riesenfeld, S. J.; Hofree, M.; Aggelakopoulou, M.; Subramanian, A.; Kuttikkatte, S. B.; Attfield, K. E.; Desel, C. A. E.; Davies, J. L.; Evans, H. G.; Avraham-Davidi, I.; Nguyen, L. T.; Dionne, D. A.; Neumann, A. E.; Jensen, L. T.; Barber, T. R.; Soilleux, E.; Carrington, M.; McVean, G.; Rozenblatt-Rosen, O.; Regev, A.; Fugger, L.

10.1101/2021.03.26.437292 — immunology — Posted on 2021-03-28

670 Histone H3 dopaminylation in ventral tegmental area underlies heroin-induced maladaptive plasticity

Maze, I.; Fulton, S. L.; Mitra, S.; Lepack, A. E.; Martin, J. A.; Dietz, D. M.

10.1101/2021.03.26.437235 — neuroscience — Posted on 2021-03-28

671 Verticillium dahliae effector VDAL protects MYB6 from degradation by interacting with PUB25/26 E3 ligases for enhancing Verticillium wilt resistance in Arabidopsis

Gong, Z.; Qi, J.; Ma, A.; Zhang, D.; Wang, G.; Wang, K.; Gao, Y.; Li, H.; Bian, C.; Cheng, J.; Yang, S.; Han, Y.; Li, Z.

10.1101/2021.03.26.437179 — plant biology — Posted on 2021-03-28

672 Exploring functional diversity of Nicotiana tabacum Aquaporins

De Rosa, A.; Evans, J. R.; Groszmann, M.

10.1101/2021.03.26.437249 — plant biology — Posted on 2021-03-28

673 Evaluation of the effect of hydrocortisone in 2D and 3D HEp-2 cell culture

Fonseca, M. O.; Godoi, B. H.; da Silva, N. S.; Pacheco-Soares, C.

10.1101/2021.03.26.437247 — cancer biology — Posted on 2021-03-28

674 Tribbles 2 confers enzalutamide resistance in prostate cancer by promoting lineage plasticity.

Monga, J.; Adrianto, I.; Rogers, C.; Gadgeel, S.; Chitale, D.; Alumkal, J.; Beltran, H.; Zoubeidi, A.; Ghosh, J.

10.1101/2021.03.26.437250 — cancer biology — Posted on 2021-03-28

675 Single-nuclei transcriptomes from human adrenal gland reveals distinct cellular identities of low and high-risk neuroblastoma tumors.

Bedoya-Reina, O. C.; Li, W.; Arceo, M.; Plescher, M.; Bullova, P.; Pui, H.; Kaucka, M.; Kharchenko, P.; Martinsson, T.; Holmberg, J.; Adameyko, I.; Deng, Q.; Larsson, C.; Juhlin, C.; Kogner, P.; Schlisio, S.

10.1101/2021.03.26.437162 — cancer biology — Posted on 2021-03-28

676 Regulatory FOXP3+ T cells in uterine sarcomas are associated with favorable prognosis, low extracellular matrix expression and reduced YAP activation

Gultekin, O.; Gonzalez-Molina, J.; Hardell, E.; Moyano-Galceran, L.; Mitsios, N.; Mulder, J.; Kokaraki, G.; Isaksson, A.; Sarhan, D.; Lehti, K.; Carlson, J. W.

10.1101/2021.03.26.437169 — cancer biology — Posted on 2021-03-28

677 Thermoplasmonic nano-rupture of cells reveals Annexin V function in plasma membrane repair

Moreno-Pescador, G. S.; Aswad, D. S.; Florentsen, C. D.; Bahadori, A.; Arastoo, M. R.; Danielsen, H. M. D.; Heitmann, A. S. B.; Boye, T. L.; Nylandsted, J.; Oddershede, L. B.; Bendix, P. M.

10.1101/2021.03.26.436963 — biophysics — Posted on 2021-03-28

678 AHLF: ad hoc learning of peptide fragmentation from mass spectra enables an interpretable detection of phosphorylated and cross-linked peptides

Altenburg, T.; Giese, S.; Wang, S.; Muth, T.; Renard, B. Y.

10.1101/2020.05.19.101345 — bioinformatics — Posted on 2021-03-28

679 A second specificity-determining loop in Class A sortases: Biochemical characterization of natural sequence variation in chimeric SrtA enzymes

Piper, I. M.; Struyvenberg, S. A.; Valgardson, J. D.; Johnson, D. A.; Gao, M.; Johnston, K.; Svendsen, J. E.; Kodama, H. M.; Hvorecny, K. L.; Antos, J. M.; Amacher, J. F.

10.1101/2021.03.27.437355 — biochemistry — Posted on 2021-03-28

680 The formation of the bacterial RNA polymerase-promoter open complex involves a branched pathway

Malinen, A. M.; Bakermans, J.; Aalto-Setälä, E.; Blessing, M.; Bauer, D. L.; Parilova, O.; Belogurov, G. A.; Dulin, D.; Kapanidis, A. N.

10.1101/2021.03.27.437306 — biochemistry — Posted on 2021-03-28

681 Manifestations of genetic risk for Alzheimer's Disease in the blood: a cross-sectional multi-omic analysis in healthy adults aged 18-90+

10.1101/2021.03.26.437267 — genetics — Posted on 2021-03-28

682 A Synthesis of Game Theory and Quantitative Genetic Models of Social Evolution

McGlothlin, J. W.; Akcay, E.; Brodie, E. D.; Moore, A. J.; Van Cleve, J.

10.1101/2021.03.27.437341 — evolutionary biology — Posted on 2021-03-28

683 Transcriptome-based phylogeny and whole-genome duplication in Theaceae

Zhang, Q.; Zhao, L.; Zhao, J.-L.; Folk, R. A.; Zamora, N.; Soltis, P. S.; Soltis, D. E.; Yang, S.-X.; Gao, L.-M.; Peng, H.; Yu, X.-Q.

10.1101/2021.03.26.437128 — evolutionary biology — Posted on 2021-03-28

684 Host genetic control of succession in the switchgrass leaf fungal microbiome

VanWallendael, A.; Benucci, G. M. N.; da Costa, P. B.; Fraser, L.; Bonito, G.; Fritschi, F. B.; Juenger, T. E.; Lovell, J. T.; Sreedasyam, A.; Lowry, D.

10.1101/2021.03.26.437207 — ecology — Posted on 2021-03-28

685 Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth

Wiche Salinas, T. R.; Zhang, Y.; Sarnello, D.; Zhyvoloup, A.; Raymond-Marchand, L.; Planas, D.; Lodha, M.; Chatterjee, D.; Karwacz, K.; Oxenford, S.; Routy, J.-P.; Amrine-Madsen, H.; Ancuta, P.; Fassati, A.

10.1101/2021.03.27.435072 — microbiology — Posted on 2021-03-28

686 Rapid evolutionary turnover of mobile genetic elements drives microbial resistance to viruses

Hussain, F. A.; Dubert, J.; Elsherbini, J.; Murphy, M.; VanInsberghe, D.; Arevalo, P.; Kauffman, K.; Kotska Rodino-Janeiro, B.; Polz, M.

10.1101/2021.03.26.437281 — microbiology — Posted on 2021-03-28

687 Chromatic bacteria version 2 - A Himar1 transposon based delivery vector to extend the host range of a toolbox to fluorescently tag bacteria

Stocks, C. F.; Schlechter, R. O.; Remus-Emsermann, M. N. P.

10.1101/2021.03.26.437257 — microbiology — Posted on 2021-03-28

688 The Detection of Bergeyella zoohelcum in Young Children after Cat Bite

Hu, M.; Li, H.; Hu, T.; Zhou, S.-Y.; Yang, Z.; Fan, C.-L.; Bao, R.; Shi, J.-G.; Zhao, K.-B.

10.1101/2021.03.26.437298 — microbiology — Posted on 2021-03-28

689 Bulk-assembly of monodisperse coacervates and giant unilamellar vesicles with programmable hierarchical complexity

Li, Q.; Song, Q.; Wei, J.; Cao, Y.; Cui, X.; Chen, D.; Shum, H. C.

10.1101/2021.02.19.432011 — synthetic biology — Posted on 2021-03-28

690 Purkinje Cell Activity During Suppression of Voluntary Eye Movements in Rhesus Macaques

Avila, E.; Flierman, N.; Holland, P. J.; Roelfsema, P. J.; Frens, M. A.; Badura, A.; De Zeeuw, C. I.

10.1101/2021.03.26.437236 — neuroscience — Posted on 2021-03-27

691 Modulation masking and fine structure shape neural envelope coding to predict speech intelligibility across diverse listening conditions

Viswanathan, V.; Bharadwaj, H. M.; Shinn-Cunningham, B. G.; Heinz, M. G.

10.1101/2021.03.26.437273 — neuroscience — Posted on 2021-03-27

692 Dopaminergic regulation of vestibulo-cerebellar circuits through unipolar brush cells

Canton-Josh, J. E.; Qin, J.; Kozorovitskiy, Y.

10.1101/2021.03.26.437266 — neuroscience — Posted on 2021-03-27

693 Learning brain dynamics for decoding and predicting individual differences

Pessoa, L.; Limbachia, C.; Misra, J.; Surampudi, S. G.; Venkatesh, M.; Jaja, J.

10.1101/2021.03.27.437315 — neuroscience — Posted on 2021-03-27

694 Structural variant selection for high-altitude adaptation using single-molecule long-read sequencing

10.1101/2021.03.27.436702 — genomics — Posted on 2021-03-27

695 PseudotimeDE: inference of differential gene expression along cell pseudotime with well-calibrated p-values from single-cell RNA sequencing data

Song, D.; Li, J. J.

10.1101/2020.11.17.387779 — bioinformatics — Posted on 2021-03-27

696 Reparative macrophages regulate fibrosis in the infarcted myocardium by attenuating apoptosis and senescence of fibroblasts

Shiraishi, M.; Yamaguchi, A.; Suzuki, K.

10.1101/2021.01.29.428912 — molecular biology — Posted on 2021-03-27

697 GABA facilitates spike propagation at branch points of sensory axons in the spinal cord

10.1101/2021.01.20.427494 — neuroscience — Posted on 2021-03-27

698 Fast and statistically robust cell extraction from large-scale neural calcium imaging datasets

Inan, H.; Schmuckermair, C.; Tasci, T.; Ahanonu, B.; Hernandez, O.; Lecoq, J.; Dinc, F.; Wagner, M. J.; Erdogdu, M.; Schnitzer, M. J.

10.1101/2021.03.24.436279 — neuroscience — Posted on 2021-03-27

699 The retrosplenial cortex combines internal and external cues to encode head velocity during navigation

Keshavarzi, S.; Bracey, E. F.; Faville, R. A.; Campagner, D.; Tyson, A. L.; Lenzi, S. C.; Branco, T.; Margrie, T. W.

10.1101/2021.01.22.427789 — neuroscience — Posted on 2021-03-27

700 The plate-to-rod transition in trabecular bone loss is elusive

Felder, A.; Monzem, S.; De Souza, R.; Javaheri, B.; Mills, D.; Boyde, A.; Doube, M.

10.1101/2020.05.14.081042 — physiology — Posted on 2021-03-27

701 Gut markers of bodily self-consciousness

Monti, A.; Porciello, G.; Panasiti, M. S.; Aglioti, S. M.

10.1101/2021.03.05.434072 — physiology — Posted on 2021-03-27

702 A graph neural network model to estimate cell-wise metabolic flux using single cell RNA-seq data

Alghamdi, N.; Chang, W.; Dang, P.; Lu, X.; Wan, C.; Gampala, S.; Huang, Z.; Wang, J.; Ma, Q.; Fishel, M. L.; Zang, Y.; Cao, S.; Zhang, C.

10.1101/2020.09.23.310656 — bioinformatics — Posted on 2021-03-27

703 Crotamine as a vehicle for non-viral gene delivery for Pompe disease

Martiniuk, F.; Mack, A.; Martiniuk, J.; Karpel, R.; Meinke, P.; Schoser, B.; Wu, F.; Tchou-Wong, K.-M.

10.1101/2021.03.23.436632 — genetics — Posted on 2021-03-27

704 α2δ-2 is Required for Functional Postsynaptic Calcium Channel Nanodomain Signaling

Beeson, K.; Westbrook, G.; Schnell, E.

10.1101/2021.03.25.437080 — neuroscience — Posted on 2021-03-27

705 Robust, Fiducial-Free Drift Correction for Super-resolution Imaging

Wester, M. J.; Schodt, D. J.; Mazloom-Farsibaf, H.; Fazel, M.; Pallikkuth, S.; Lidke, K. A.

10.1101/2021.03.26.437196 — biophysics — Posted on 2021-03-27

706 RNA polymerase II depletion from the inactive X chromosome territory is not mediated by physical compartmentalization.

Collombet, S.; Rall, I.; Dugast-Darzacq, C.; Heckert, A.; Halavatyi, A.; le Saux, A.; Dailey, G.; Darzacq, X.; Heard, E.

10.1101/2021.03.26.437188 — developmental biology — Posted on 2021-03-27

707 Signal requirement for cortical potential of transplantable human neuroepithelial stem cells

Varga, B. V.; Faiz, M.; Yang, H.; Pivonkova, H.; Gao, S.; Khelifi, G.; Linderoth, E.; Zhen, M.; Hussein, S. M. I.; Nagy, A.

10.1101/2021.03.27.437311 — developmental biology — Posted on 2021-03-27

708 Rbf/E2F1 control growth and endoreplication via steroid-independent Ecdysone Receptor signalling in Drosophila prostate-like secondary cells

Sekar, A.; Leiblich, A.; Hellberg, J. E. E. U.; Sarma, D.; Mendes, C. C.; Wainwright, M. S.; Gandy, C.; Goberdhan, D. C. I.; Hamdy, F. C.; Wilson, C.

10.1101/2021.03.27.437310 — cell biology — Posted on 2021-03-27

709 Stress-driven tissue fluidization physically segments vertebrate somites

Shelton, E.; Kim, S.; Gross, B. J.; Wu, R.; Pochitaloff, M.; Lim, I.; Sletten, E. M.; Campas, O.

10.1101/2021.03.27.437325 — biophysics — Posted on 2021-03-27

710 High Throughput Virtual Screening and Validation of a SARS-CoV-2 Main Protease Non-Covalent Inhibitor

Clyde, A.; Galanie, S.; Kneller, D. W.; Ma, H.; Babuji, Y.; Blaiszik, B.; Brace, A.; Brettin, T.; Chard, K.; Chard, R.; Coates, L.; Foster, I.; Hauner, D.; Kertesz, V.; Kumar, N.; Lee, H.; Li, Z.; Merzky, A.; Schmidt, J. G.; Tan, L.; Titov, M.; Trifan, A.; Turilli, M.; Van Dam, H.; Chennubhotla, S. C.; Jha, S.; Kovalevsky, A.; Ramanathan, A.; Head, M.; Stevens, R.

10.1101/2021.03.27.437323 — biophysics — Posted on 2021-03-27

711 Single-cell motion of magnetotactic bacteria in microfluidic confinement: interplay between surface interaction and magnetic torque

Codutti, A.; Charsooghi, M. A.; Cerda-Donate, E.; Taïeb, H. M.; Robinson, T.; Faivre, D.; Klumpp, S.

10.1101/2021.03.27.437322 — biophysics — Posted on 2021-03-27

712 The nucleotide addition cycle of the SARS-CoV-2 polymerase

Bera, S. C.; Seifert, M.; Kirchdoerfer, R.; van Nies, P.; Wubulikasimu, Y.; Quack, S.; Papini, F. S.; Arnold, J. J.; Canard, B.; Cameron, C. E.; Depken, M.; Dulin, D.

10.1101/2021.03.27.437309 — biophysics — Posted on 2021-03-27

713 Validating Pore Size Estimates in a Complex Microfibre Environment on a Human MRI System

Huang, C.-C.; Hsu, C.-C. H.; Zhou, F.-L.; Kusmia, S.; Drakesmith, M.; Parker, G. J. M.; Lin, C.-P.; Jones, D. K.

10.1101/2021.03.27.437304 — biophysics — Posted on 2021-03-27

714 Rapid Evolution of SARS-CoV-2 Challenges Human Defenses

Duarte, C. M.; Ketcheson, D.; Eguiluz, V. M.; Agusti, S. R.; Gracia, J. F.; Jamil, T.; Laiolo, E.; Gojobori, T.; Alam, I.

10.1101/2021.03.27.437300 — evolutionary biology — Posted on 2021-03-27

715 In vivo regulation of fluorescent fusion proteins by engineered kinases

Lepeta, K. J.; Roubinet, C. J.; Kanca, O.; Ochoa-Espinosa, A.; Bieli, D.; Cabernard, C.; Affolter, M.; Caussinus, E.

10.1101/2021.03.26.433940 — developmental biology — Posted on 2021-03-27

716 Insights into in vivo adipocyte differentiation through cell-specific labeling in zebrafish

Lepanto, P.; Levin-Ferreyra, F.; Koziol, U.; Malacrida, L.; Badano, J. L.

10.1101/2021.03.26.437287 — developmental biology — Posted on 2021-03-27

717 In vivo dissection of Rhoa function in vascular development using zebrafish

Pillay, L. M.; Yano, J. J.; Davis, A. E.; Butler, M. G.; Barnes, K. A.; Reyes, V. L.; Castranova, D.; Gore, A. V.; Swift, M. R.; Iben, J. R.; Stratman, A. N.; Weinstein, B. M.

10.1101/2021.03.27.437282 — developmental biology — Posted on 2021-03-27

718 Mass Cytometric and Transcriptomic Profiling of Epithelial-Mesenchymal Transitions in Human Mammary Cell Lines

Wagner, J.; Masek, M.; Jacobs, A.; Soneson, C.; Damond, N.; de Souza, N.; Robinson, M. D.; Bodenmiller, B.

10.1101/2021.03.26.436976 — cell biology — Posted on 2021-03-27

719 Internalisation and biological activity of nucleic acids delivering cell-penetrating peptide nanoparticles is controlled by the biomolecular corona

Lorents, A.; Maloverjan, M.; Padari, K.; Pooga, M.

10.1101/2021.03.26.437157 — cell biology — Posted on 2021-03-27

720 aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete β-arrestin-2 mediated SphK1-S1PR1-Akt signaling axis

Molinar-Inglis, O.; Birch, C. A.; Nicholas, D.; Cisneros-Aguirre, M.; Patwardhan, A.; Chen, B.; Grimsey, N. J.; Gomez-Menzies, P. K.; Lin, H.; Coronel, L. J.; Lawson, M. A.; Patel, H. H.; Trejo, J.

10.1101/2021.03.27.437291 — cell biology — Posted on 2021-03-27

721 Antidepressants are complex regulators of lipoprotein(a) macropinocytosis

Redpath, G. M. I.; Deo, N.; Siddiqui, H.; Madani, G.; Kapoor-Kaushik, N.; Ariotti, N.; Rutledge, M.; Williams, M.; McCormick, S. P.

10.1101/2021.03.26.437114 — cell biology — Posted on 2021-03-27

722 The RNA sensor MDA5 detects SARS-CoV-2 infection

Sampaio, N. G.; Chauveau, L.; Hertzog, J.; Bridgeman, A.; Fowler, G.; Moonen, J. P.; Dupont, M.; Russel, R. A.; Noerenberg, M.; Rehwinkel, J.

10.1101/2021.03.26.437180 — immunology — Posted on 2021-03-27

723 Mechanism of a COVID-19 nanoparticle vaccine candidate that elicits a broadly neutralizing antibody response to SARS-CoV-2 variants

Zhang, Y.-N.; Paynter, J.; Fourfouris, T.; Sou, C.; Ngo, T.; He, L.; Zhu, J.

10.1101/2021.03.26.437274 — immunology — Posted on 2021-03-27

724 TMPRSS2 inhibitor discovery facilitated through an in silico and biochemical screening platform

Peiffer, A. L.; Garlick, J. M.; Wu, Y.; Soellner, M. B.; Brooks, C. L.; Mapp, A. K.

10.1101/2021.03.22.436465 — biochemistry — Posted on 2021-03-27

725 In vitro and in vivo preclinical studies predict REGEN-COV protection against emergence of viral escape in humans

Copin, R.; Baum, A.; Wloga, E.; Pascal, K. E.; Giordano, S.; Fulton, B. O.; Zhou, A.; Negron, N.; Lanza, K.; Chan, N.; Coppola, A.; Chiu, J.; Ni, M.; Atwal, G. S.; Romero Hernandez, A.; Saotome, K.; Zhou, Y.; Franklin, M. C.; Hooper, A. T.; McCarthy, S.; Hamon, S.; Hamilton, J. D.; Staples, H. M.; Alfson, K.; Carrion, R.; Ali, S.; Norton, T.; Somersan-Karakaya, S.; Sivapalasingam, S.; Herman, G. A.; Weinreich, D. M.; Lipsich, L.; Stahl, N.; Murphy, A. J.; Yancopoulos, G. D.; Kyratsous, C. A.

10.1101/2021.03.10.434834 — microbiology — Posted on 2021-03-27

726 An optimized tissue clearing protocol for rat brain labeling, imaging, and high throughput analysis

Branch, A.; Tward, D.; Kolstad, A.; Pulyadi, V.; Vogelstein, J. T.; Wu, Z.; Gallagher, M.

10.1101/639674 — neuroscience — Posted on 2021-03-27

727 High trait variability in optimal polygenic prediction strategy within multiple-ancestry cohorts

Lehmann, B. C.; Mackintosh, M.; McVean, G.; Holmes, C. C.

10.1101/2021.01.15.426781 — genomics — Posted on 2021-03-27

728 A phylogenomic perspective on gene tree conflict and character evolution in Caprifoliaceae using target enrichment data, with Zabelioideae recognized as a new subfamily

Wang, H.; Morales-Briones, D. F.; Moore, M. J.; Wen, J.; Wang, H.

10.1101/2020.10.29.359950 — evolutionary biology — Posted on 2021-03-27

729 The discriminatory power of the T cell receptor

Pettmann, J.; Huhn, A.; Abu-Shah, E.; Kutuzov, M. A.; Wilson, D. B.; Dustin, M.; Davis, S.; van der Merwe, P. A.; Dushek, O.

10.1101/2020.11.16.384495 — immunology — Posted on 2021-03-27

730 Cortical Silent Period reflects individual differences in action stopping performance.

Paci, M.; Di Cosmo, G.; Ferri, F.; Costantini, M.

10.1101/2020.07.28.219600 — neuroscience — Posted on 2021-03-27

731 Tooth chipping patterns in Paranthropus do not support regular hard food mastication

Towle, I.; Irish, J. D.; Loch, C.

10.1101/2021.02.12.431024 — paleontology — Posted on 2021-03-27

732 Low-cost drug discovery with engineered E. coli reveals an anti-mycobacterial activity of benazepril

Bongaerts, N.; Edoo, Z.; Abukar, A. A.; Song, X.; Sosa Carrillo, S.; Lindner, A. B.; Wintermute, E. H.

10.1101/2021.03.26.437171 — synthetic biology — Posted on 2021-03-27

733 Unsaturated fatty acids augment protein transport via the SecA:SecYEG translocon

Kamel, M.; Löwe, M.; Schott-Verdugo, S.; Gohlke, H.; Kedrov, A.

10.1101/2021.03.26.437172 — biophysics — Posted on 2021-03-27

734 CM1-driven assembly and activation of Yeast γ-Tubulin Small Complex underlies microtubule nucleation

Brilot, A. F.; Lyon, A.; Zelter, A.; Viswanath, S.; Maxwell, A.; MacCoss, M. J.; Muller, E. G.; Sali, A.; Davis, T. N.; Agard, D. A.

10.1101/2020.11.21.392803 — biochemistry — Posted on 2021-03-27

735 Unification of Sparse Bayesian Learning Algorithms for Electromagnetic Brain Imaging with the Majorization Minimization Framework

Hashemi, A.; Cai, C.; Kutyniok, G.; Müller, K.-R.; Nagarajan, S.; Haufe, S.

10.1101/2020.08.10.243774 — neuroscience — Posted on 2021-03-27

736 Sex disparities in influenza: a multiscale network analysis

Wang, C.; Lashua, L. P.; Carter, C. E.; Johnson, S. K.; Wang, M.; Ross, T. M.; Ghedin, E.; Zhang, B.; Forst, C. V.

10.1101/2021.03.25.437108 — systems biology — Posted on 2021-03-27

737 Inferring cell cycle phases from a partially temporal network of protein interactions

Lucas, M.; Morris, A.; Townsend-Teague, A.; Tichit, L.; Habermann, B. H.; Barrat, A.

10.1101/2021.03.26.437187 — systems biology — Posted on 2021-03-27

738 Pellaea zygophylla, a new combination for a distinctive & well-known but neglected fern.

Alexander, P. J.

10.1101/2021.03.25.437027 — plant biology — Posted on 2021-03-27

739 Apparent sunk cost effect in rational agents

Ott, T.; Masset, P.; Gouvea, T. S.; Kepecs, A.

10.1101/2021.03.26.437119 — animal behavior and cognition — Posted on 2021-03-27

740 Differential effects of loss of park7 activity on Iron Responsive Element (IRE) gene sets: Implications for the role of iron dyshomeostasis in the pathophysiology of Parkinson's disease

Chin, H. Y.; Lardelli, M.; Collins-Praino, L.; Barthelson, K.

10.1101/2021.03.25.437102 — genetics — Posted on 2021-03-27

741 Effects of stochasticity on the length and behaviour of ecological transients

Hastings, A.; Abbott, K. C.; Cuddington, K.; Francis, T.; Lai, Y.-C.; Morozov, A.; Petrovskii, S.; Zeeman, M. L.

10.1101/2021.03.25.437077 — ecology — Posted on 2021-03-26

742 TOWARDS QUANTITATIVE FORECASTING OF SPECIES YIELDS WITH INCOMPLETE INFORMATION ON MODEL PARAMETERS

Fort, H.

10.1101/2021.03.25.437089 — ecology — Posted on 2021-03-26

743 Higher-order interactions among coinfecting parasites and a microbial mutualist impact disease progression

O'Keeffe, K. R.; Simha, A.; Mitchell, C. E.

10.1101/2021.03.25.437101 — ecology — Posted on 2021-03-27

744 Curvature sensing steers actin-driven cell migration

Sitarska, E.; Dias Almeida, S.; Beckwith, M.; Stopp, J.; Schwab, Y.; Sixt, M.; Kreshuk, A.; Erzberger, A.; Diz-Munoz, A.

10.1101/2021.03.26.437199 — cell biology — Posted on 2021-03-26

745 Plasma membrane damage limits replicative lifespan in yeast and human fibroblasts

Kono, K.; Johmura, Y.; Moriyama, Y.; Masukagami, Y.; Nishimura, K.; Barbee, H.; Takase, H.; Sugiyama, S.; Sato, Y.; Higashiyama, T.; Nakanishi, M.

10.1101/2021.03.26.437120 — cell biology — Posted on 2021-03-27

746 In vivo photocontrol of microtubule dynamics and integrity, migration and mitosis, by the potent GFP-imaging-compatible photoswitchable reagents SBTubA4P and SBTub2M

Gao, L.; Meiring, J. C. M.; Varady, A.; Ruider, I. E.; Heise, C.; Wranik, M.; Velasco, C. D.; Taylor, J. A.; Terni, B.; Standfuss, J.; Cabernard, C. C.; Llobet, A.; Steinmetz, M. O.; Bausch, A. R.; Distel, M.; Thorn-Seshold, J.; Akhmanova, A.; Thorn-Seshold, O.

10.1101/2021.03.26.437160 — cell biology — Posted on 2021-03-27

747 Epithelial Regeneration Ability of Crohn's Disease Assessed Using Patient-Derived Intestinal Organoids

Lee, C.; Hong, S. N.; Kim, E. R.; Chang, D. K.; Kim, Y.-H.

10.1101/2021.03.25.437111 — cell biology — Posted on 2021-03-27

748 Purkinje Cell Activity During Suppression of Voluntary Eye Movements in Rhesus Macaques

Avila, E.; Flierman, N.; Holland, P. J.; Roelfsema, P. J.; Frens, M. A.; Badura, A.; De Zeeuw, C. I.

10.1101/2021.03.26.437236 — neuroscience — Posted on 2021-03-26

749 Your pleasure is mine; when people share amusical emotional experience during a livemusic performance in a concert hall.

Chabin, T.; Gabriel, D.; Comte, A.; Haffen, E.; Moulin, T.; Pazart, L.

10.1101/2021.03.26.436975 — neuroscience — Posted on 2021-03-26

750 Functional selectivity for naturalistic social interaction perception in the human superior temporal sulcus

Lee Masson, H.; Isik, L.

10.1101/2021.03.26.437258 — neuroscience — Posted on 2021-03-26

751 Pseudohydrosme bogneri sp. nov. (Araceae), a spectacular Critically Endangered (Possibly Extinct) species from Gabon, long confused with Anchomanes nigritianus.

Moxon-Holt, L.; Cheek, M.

10.1101/2021.03.25.437040 — plant biology — Posted on 2021-03-26

752 A Statistical Model for Describing and Simulating Microbial Community Profiles

Ma, S.; Ren, B.; Mallick, H.; Moon, Y. S.; Schwager, E.; Maharjan, S.; Tickle, T. L.; Lu, Y.; Carmody, R. N.; Franzosa, E. A.; Janson, L.; Huttenhower, C.

10.1101/2021.03.26.437146 — bioinformatics — Posted on 2021-03-26

753 SongExplorer: A deep learning workflow for discovery and segmentation of animal acoustic communication signals

Arthur, B. J.; Ding, Y.; Sosale, M.; Khalif, F.; Kim, E.; Waddell, P.; Turaga, S. C.; Stern, D.

10.1101/2021.03.26.437280 — animal behavior and cognition — Posted on 2021-03-26

754 Massive loss of transcription factors and the initial diversification of placental mammals

Zhao, X.-W.; Wu, J.; Kishino, H.

10.1101/2021.03.26.436744 — evolutionary biology — Posted on 2021-03-26

755 Drift as a driver of language change: An artificial language experiment

Ventura, R.; Plotkin, J. B.; Roberts, G.

10.1101/2021.03.26.437270 — evolutionary biology — Posted on 2021-03-26

756 The anthropometric and physical qualities of womens rugby league Super League and international players; identifying differences in playing position and standard

Scantlebury, S.; McCormack, S.; Sawczuk, T.; Emmonds, S.; Collins, N.; Beech, J.; Ramirez, C.; Owen, C.; Jones, B.

10.1101/2021.03.26.437147 — physiology — Posted on 2021-03-26

757 STRESS, an automated geometrical characterization of deformable particles for in vivo measurements of cell and tissue mechanical stresses

Gross, B.; Shelton, E.; Gomez, C.; Campas, O.

10.1101/2021.03.26.437148 — biophysics — Posted on 2021-03-26

758 Development and Validation of Fluorescently Labeled, Functional Type I Collagen Molecules

Siadat, S. M.; Susilo, M. E.; Paten, J. A.; Silverman, A. A.; DiMarzio, C. A.; Ruberti, J. W.

10.1101/2021.03.26.437209 — molecular biology — Posted on 2021-03-26

759 Recurrent chromosomal translocations in sarcomas create a mega-complex that mislocalizes NuA4/TIP60 to Polycomb target loci

Sudarshan, D.; Avvakumov, N.; Lalonde, M.-E.; Alerasool, N.; Jacquet, K.; Mameri, A.; Rousseau, J.; Lambert, J.-P.; Paquet, E.; Setty, S. T.; Loehr, J.; Gingras, A.-C.; Coulombe, B.; Taipale, M.; Doyon, Y.; Cote, J.

10.1101/2021.03.26.436670 — molecular biology — Posted on 2021-03-26

760 Failure of the brain glucagon-like peptide-1-mediated control of intestinal redox homeostasis in a rat model of sporadic Alzheimer's disease

Homolak, J.; Babic Perhoc, A.; Knezovic, A.; Osmanovic Barilar, J.; Salkovic-Petrisic, M.

10.1101/2021.03.22.436453 — neuroscience — Posted on 2021-03-26

761 A role for reward valuation in the serotonergic modulation of impulsivity

Desrochers, S. S.; Lesko, E. K.; Magalong, V. M.; Balsam, P. D.; Nautiyal, K. M.

10.1101/2020.01.17.910778 — neuroscience — Posted on 2021-03-26

762 CM1-driven assembly and activation of Yeast γ-Tubulin Small Complex underlies microtubule nucleation

Brilot, A. F.; Lyon, A.; Zelter, A.; Viswanath, S.; Maxwell, A.; MacCoss, M. J.; Muller, E. G.; Sali, A.; Davis, T. N.; Agard, D. A.

10.1101/2020.11.21.392803 — biochemistry — Posted on 2021-03-26

763 The salmon louse genome: copepod features and parasitic adaptations.

Skern-Mauritzen, R.; Malde, K.; Eichner, C.; Dondrup, M.; Furmanek, T.; Besnier, F.; Komisarczuk, A. Z.; Nuhn, M.; Dalvin, S.; Edvardsen, R. B.; Klages, S.; Huettel, B.; Stueber, K.; Grotmol, S.; Karlsbakk, E.; Kersey, P.; Leong, J. S.; Glover, K. A.; Reinhardt, R.; Lien, S.; Jonassen, I.; Koop, B. F.; Nilsen, F.

10.1101/2021.03.15.435234 — genomics — Posted on 2021-03-26

764 Antiviral Antibody Epitope Selection is a Heritable Trait

Venkataraman, T.; Valencia, C.; Mangino, M.; Morgenlander, W.; Clipman, S. J.; Liechti, T.; Valencia, A.; Christofidou, P.; Spector, T. D.; Roederer, M.; Duggal, P.; Larman, H. B.

10.1101/2021.03.25.436790 — genetics — Posted on 2021-03-26

765 Genetic Variant in 3' Untranslated Region of the Mouse Pycard Gene Regulates Inflammasome Activity

Ritchey, B.; Hai, Q.; Han, J.; Barnard, J.; Smith, J. D.

10.1101/2021.03.26.437184 — genetics — Posted on 2021-03-26

766 RNA chaperones Hfq and ProQ play a key role in the virulence of the plant pathogenic bacterium Dickeya dadantii

Leonard, S.; Villard, C.; Nasser, W.; Reverchon, S.; Hommais, F.

10.1101/2021.03.26.437193 — microbiology — Posted on 2021-03-26

767 Bacterial small RNAs and host epigenetic effectors of a transgenerational memory of pathogens in C. elegans.

Legüe, M. E.; Aguila, B.; Pollak, B.; Calixto, A.

10.1101/2021.03.26.437277 — microbiology — Posted on 2021-03-26

768 Differential viral RNA methylation contributes to pathogen blocking in Wolbachia-colonized arthropod

Bhattacharya, T.; Yan, L.; Zaher, H.; Newton, I. L. G.; Hardy, R. W.

10.1101/2021.03.26.437201 — microbiology — Posted on 2021-03-26

769 Metagenomic insight into the plant growth-promoting potential of a diesel-degrading bacterial consortium for enhanced rhizoremediation application

Eze, M. O.; Thiel, V.; Hose, G. C.; George, S. C.; Daniel, R.

10.1101/2021.03.26.437261 — microbiology — Posted on 2021-03-26

770 Overabundance of Asaia and Serratia bacteria is associated with deltamethrin insecticide susceptibiltiy in Anopheles coluzzii from Agboville, Cote d'Ivoire

Pelloquin, B.; Kristan, M.; Edi, C.; Meiwald, A.; Clark, E.; Jeffries, C. L.; Walker, T.; Dada, N.; Messenger, L. A.

10.1101/2021.03.26.437219 — microbiology — Posted on 2021-03-26

771 Copper intoxication in group B Streptococcus triggers a mis-metallation signature and activation of the cop operon leading to enhanced virulence

Sullivan, M. J.; Goh, K. G.; Gosling, D.; Katupitiya, L.; Ulett, G. C.

10.1101/2021.03.25.437115 — microbiology — Posted on 2021-03-26

772 Sex differences in concentrations of HMGB1 and numbers of pigmented monocytes in infants with malaria

Kanoi, B. N.; Egwang, T. G.

10.1101/2021.03.26.437109 — immunology — Posted on 2021-03-26

773 Deep generative selection models of T and B cell receptor repertoires with soNNia

Isacchini, G.; Walczak, A. M.; Mora, T.; Nourmohammad, A.

10.1101/2020.11.05.370346 — immunology — Posted on 2021-03-26

774 Audiovisual adaptation is expressed in spatial and decisional codes

Aller, M.; Mihalik, A.; Noppeney, U.

10.1101/2021.02.15.431309 — neuroscience — Posted on 2021-03-26

775 Temporal attention selectively enhances target features

Ramirez, L. D.; Foster, J. J.; Ling, S.

10.1101/2021.03.25.437071 — neuroscience — Posted on 2021-03-26

776 Increased prefrontal top-down control in older adults predicts motor performance and age-group association

Loehrer, P. A.; Nettersheim, F. S.; Oehrn, C.; Homberg, F.; Tittgemeyer, M.; Timmermann, L.; Weber, I.

10.1101/2020.12.09.417568 — neuroscience — Posted on 2021-03-26

777 The Marburg Collection: A Golden Gate DNA Assembly Framework for Synthetic Biology Applications in Vibrio natriegens

Stukenberg, D.; Hensel, T.; Hoff, J.; Daniel, B.; Inckemann, R.; Tedeschi, J. N.; Nousch, F.; Fritz, G.

10.1101/2021.03.26.437105 — synthetic biology — Posted on 2021-03-26

778 Quantitative proteome and PTMome analysis of Arabidopsis thaliana root responses to persistent osmotic and salinity stress.

Rodriguez, M. C.; Mehta, D.; Tan, M.; Uhrig, R. G.

10.1101/2020.12.28.424236 — plant biology — Posted on 2021-03-26

779 Systematic Profiling of Temperature- and Retinal-Sensitive Rhodopsin Variants by Deep Mutational Scanning

McKee, A. G.; Kuntz, C. P.; Ortega, J. T.; Woods, H.; Roushar, F. J.; Meiler, J.; Jastrzebska, B.; Schlebach, J. P.

10.1101/2021.03.26.437229 — biophysics — Posted on 2021-03-26

780 Norstictic acid is a selective allosteric transcriptional regulator

Garlick, J. M.; Sturlis, S. M.; Bruno, P. A.; Yates, J. A.; Peiffer, A.; Liu, Y.; Goo, L.; Bao, L.; De Salle, S.; Tamayo-Castillo, G.; Brooks, C. L.; Merajver, S. D.; Mapp, A. K.

10.1101/2021.03.26.437253 — biochemistry — Posted on 2021-03-26

781 A simple micropreparative gel electrophoresis technique for purification of proteins, nucleic acids, and bioconjugates

Sajjadi, S. H.; Wu, S.-J.; Zubkovs, V.; Ahmadzadeh, H.; K. Goharshadi, E.; Boghossian, A. A.

10.1101/2021.03.26.436431 — biochemistry — Posted on 2021-03-26

782 Biochemical and Immuno-Histochemical Localization of Type IIA Procollagen in Annulus Fibrosus of Mature Bovine Intervertebral Disc

McAlinden, A.; Hudson, D. M.; Fernandes, A. A.; Ravindran, S.; Fernandes, R. J.

10.1101/2021.03.26.437279 — biochemistry — Posted on 2021-03-26

783 Characterizing nucleotide variation and expansion dynamics in human-specific variable number tandem repeats

Course, M. M.; Sulovari, A.; Gudsnuk, K.; Eichler, E. E.; Valdmanis, P. N.

10.1101/2021.03.25.437092 — genomics — Posted on 2021-03-26

784 HIGH VIRULENCE SELECTS FOR FAST HOST RESISTANCE EVOLUTION

Wendling, C. C.; Lange, J.; Liesegang, H.; Poehlein, A.; Bunk, B.; Reikov, J.; Goehlich, H.; Roth, O.; Brockhurst, M.

10.1101/2021.03.26.437141 — evolutionary biology — Posted on 2021-03-26

785 Spatiotemporal patterns in Golden-cheeked Warbler breeding habitat quality and quantity

Dreiss, L.; Sanchez-Navarro, P.; Bird, B.

10.1101/2021.03.25.436967 — ecology — Posted on 2021-03-26

786 Quantifying isolation-by-resistance and connectivity in dendritic ecological networks

Chafin, T. K.; Mussmann, S. M.; Douglas, M. R.; Douglas, M. E.

10.1101/2021.03.25.437078 — ecology — Posted on 2021-03-26

787 TNFAIP8 is a novel phosphoinositide-binding inhibitory regulator of Rho GTPases that promotes cancer cell migration

Lin, M.; Sun, H.; Fayngerts, S. A.; Huangyang, P.; Chen, Y. H.

10.1101/2021.03.26.437243 — cell biology — Posted on 2021-03-26

788 Beyond fish eDNA metabarcoding: Field replicates disproportionately improve the detection of stream associated vertebrate species

Macher, T.-H.; Schuetz, R.; Arle, J.; Beermann, A. J.; Koschorreck, J.; Leese, F.

10.1101/2021.03.26.437227 — molecular biology — Posted on 2021-03-26

789 Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA

Petit, G. A.; Mohanty, B.; McMahon, R. M.; Nebl, S.; Hilko, D. H.; Wylde, K. L.; Scanlon, M. J.; Martin, J. L.; Halili, M. A.

10.1101/2021.03.25.436878 — molecular biology — Posted on 2021-03-26

790 Disruption of the MreB elongasome is overcome by mutations in the TCA cycle

Barton, B.; Grinnell, A.; Morgenstein, R.

10.1101/2020.06.18.160713 — microbiology — Posted on 2021-03-26

791 Thriving of hyperthermophilic microbial communities from a deep-sea sulfidic hydrothermal chimney under electrolithoautotrophic conditions with nitrate as electron acceptor.

PILLOT, G.; Davidson, S.; Shintu, L.; Tanet, L.; Combet-Blanc, Y.; Godfroy, A.; Bonin, P.; Liebgott, P.-P.

10.1101/2021.03.26.437165 — microbiology — Posted on 2021-03-26

792 Comparison of SARS-CoV-2 VOC 202012/01 (UK variant) and D614G variant transmission by different routes in Syrian hamsters

Mohandas, S.; Yadav, P.; Nyayanit, D.; Shete-Aich, A.; Sarkale, P.; Hundekar, S.; Kumar, S.; Lole, K.

10.1101/2021.03.26.437153 — microbiology — Posted on 2021-03-26

793 High diversity and heterogeneity define microbial communities across an active municipal landfill

Sauk, A.; Hug, L. A.

10.1101/2021.03.26.437222 — microbiology — Posted on 2021-03-26

794 A spatial and cellular distribution of neurotropic virus infection in the mouse brain revealed by fMOST and single cell RNA-seq

Zhang, Y.; Xing, X.; Long, B.; Cao, Y.; Hu, S.; Li, X.; Yu, Y.; Tian, D.; Luo, Z.; Sui, B.; Liu, W.; Lv, L.; Wu, Q.; Dai, J.; Zhou, M.; Han, H.; Fu, Z. F.; Gong, H.; Bai, F.; Zhao, L.

10.1101/2021.03.26.436691 — microbiology — Posted on 2021-03-26

795 Green Fluorescent Carbon Dots as Targeting Probes for LED-Dependent Bacterial Killing

Takebayashi, Y.; Samphire, J.; Hill, S. A.; Hill, N.; Heesom, K. J.; Lewis, P. A.; Alibhai, D.; Bragginton, E. C.; Dorh, J.; Dorh, N.; Spencer, J.; Galan, M. C.

10.1101/2021.03.26.437036 — microbiology — Posted on 2021-03-26

796 Rapid response of nitrogen cycling gene transcription to labile carbon amendments in a soil microbial community

Chuckran, P. F.; Fofanov, V.; Hungate, B. A.; Morrissey, E. M. A.; Schwartz, E.; Walkup, J.; Dijkstra, P.

10.1101/2021.03.26.437204 — microbiology — Posted on 2021-03-26

797 Identification of enriched hyperthermophilic microbial communities from a deep-sea hydrothermal vent chimney under electrolithoautotrophic culture conditions.

PILLOT, G.; Davidson, S.; Shintu, L.; Amin Ali, O.; Godfroy, A.; Combet-Blanc, Y.; Bonin, P.; Liebgott, P.-P.

10.1101/2020.11.11.377697 — microbiology — Posted on 2021-03-26

798 Effect of a Monascus sp. red yeast rice extract on germination of bacterial spores

Husakova, M.; Plechata, M.; Branska, B.; Patakova, P.

10.1101/2021.03.26.437149 — microbiology — Posted on 2021-03-26

799 Occurrence of COVID-19 symptoms during SARS-CoV-2 infection defines waning of humoral immunity

Wu, J.; Liang, B.; Fang, Y.; Wang, H.; Yang, X.; Shen, S.; Chen, L.; Li, S.; Lu, S.; Xiang, T.; Liu, J.; Le-Trilling, V. T. K.; Lu, M.; Yang, D.; Deng, F.; Dittmer, U.; Trilling, M.; Zheng, X.

10.1101/2021.03.26.437123 — immunology — Posted on 2021-03-26

800 U-Net Model for Brain Extraction: Trained on Humans for Transfer to Non-human Primates

Wang, X.; Li, X.-H.; Cho, J. W.; Russ, B.; Rajamani, N.; Omelchenko, A.; Ai, L.; Korchmaros, A.; Garcia-Saldivar, P.; Wang, Z.; Kalin, N. H.; Schroeder, C. E.; Craddock, R. C.; Fox, A. S.; Evans, A. C.; Messinger, A.; Milham, M. P.; Xu, T.

10.1101/2020.11.17.385898 — neuroscience — Posted on 2021-03-26

801 Electrophysiological and Transcriptomic Features Reveal a Circular Taxonomy of Cortical Neurons

Rodriguez-Collado, A.; Rueda, C.

10.1101/2021.03.24.436849 — neuroscience — Posted on 2021-03-26

802 Mitochondria-dependent phase separation of disease-relevant proteins drives pathological features of age-related macular degeneration

La Cunza, N.; Tan, L. X.; Thamban, T.; Germer, C. J.; Rathnasamy, G.; Toops, K. A.; Lakkaraju, A.

10.1101/2020.07.15.201723 — neuroscience — Posted on 2021-03-26

803 Expression of a modified astrocytic glutamate transporter alleviates Huntington hypokinesia, promotes synaptic glutamate clearance and counteracts potentially adverse EAAT2 interactions

Hirschberg, S.; Dvorzhak, A.; Rasooli-Nejad, S. M. A.; Angelov, S.; Kirchner, M.; Mertins, P.; Lättig-Tünnemann, G.; Harms, C.; Schmitz, D.; Grantyn, R.

10.1101/2020.09.17.302158 — neuroscience — Posted on 2021-03-26

804 Lateralized functional responses in the cortex arise from the dynamic interactions in the structural connectome

Kumar, N.; Jaiswal, A. K.; Roy, D.; Banerjee, A.

10.1101/2020.10.16.342360 — neuroscience — Posted on 2021-03-26

805 Improved architectures for flexible DNA production using retrons across kingdoms of life

Lopez, S. C.; Crawford, K. D.; Bhattarai-Kline, S.; Shipman, S. L.

10.1101/2021.03.26.437017 — synthetic biology — Posted on 2021-03-26

806 Off-resonance saturation as an MRI method to quantify ferritin-bound iron in the post-mortem brain

Bossoni, L.; Hegeman-Kleinn, I.; van Duinen, S. G.; Vroegindeweij, L. H. P.; Langendonk, J. G.; Hirschler, L.; Webb, A.; van der Weerd, L.

10.1101/2021.03.22.436424 — biophysics — Posted on 2021-03-26

807 D155Y Substitution of SARS-CoV-2 ORF3a Weakens Binding with Caveolin-1: An in silico Study

Gupta, S.; Mallick, D.; Banerjee, K.; Sarkar, S.; Lee, S. T. M.; Basuchowdhuri, P.; Jana, S. S.

10.1101/2021.03.26.437194 — bioinformatics — Posted on 2021-03-26

808 Immunoinformatic approach to design a vaccine against SARS-COV-2 membrane glycoprotein

Ravindran, R.

10.1101/2021.03.26.436314 — bioinformatics — Posted on 2021-03-26

809 Standardized workflow for precise mid- and high-throughput proteomics of blood biofluids

Mc Ardle, A.; Binek,, A.; Moradian, A.; Chazarin Orgel, B.; Rivas, A.; Washington, K. E.; Phebus, C.; Manalo, D.-M.; Go, J.; Venkatraman, V.; Johnson, C.; Fu, Q.; Cheng, S.; Raedschelders, K.; Fert-Bober, J.; Pennington, S. R.; Murray, C. I.; VanEyk, J. E.

10.1101/2021.03.26.437268 — biochemistry — Posted on 2021-03-26

810 An empirical pipeline for personalized diagnosis of Lafora disease mutations

Brewer, M. K.; Machio-Castello, M.; Viana, R.; Wayne, J. L.; Kuchtova, A.; Simmons, Z. R.; Sternbach, S.; Li, S.; Garcia-Gimeno, M. A.; Serratosa, J.; Sanz, P.; Vander Kooi, C. W.; Gentry, M. S.

10.1101/2021.03.26.437206 — biochemistry — Posted on 2021-03-26

811 Co-targeting strategy for precise, scarless gene editing with CRISPR/Cas9 and donor ssODNs in Chlamydomonas

Cerutti, H. D.; Akella, S.; Ma, X.; Bacova, R.; Harmer, Z.; Kolackova, M.; Wen, X.; Wright, D. A.; Spalding, M. H.; Weeks, D. P.

10.1101/2021.03.26.437214 — genetics — Posted on 2021-03-26

812 Aberrant glycosylation of anti-SARS-CoV-2 IgG is a pro-thrombotic stimulus for platelets

Bye, A. P.; Hoepel, W.; Mitchell, J. L.; Jegouic, S.; Loureiro, S.; Sage, T.; de Taeye, S.; van Gils, M.; Kriek, N.; Cooper, N.; Jones, I.; den Dunnen, J.; Gibbins, J. M.

10.1101/2021.03.26.437014 — immunology — Posted on 2021-03-26

813 Disrupting inter-subunit interactions favors channel opening in P2X2 receptors

Gasparri, F.; Bielickaite, S.; Poulsen, M. H.; Pless, S. A.

10.1101/2021.03.26.436616 — biophysics — Posted on 2021-03-26

814 Structures of Bdellovibrio bacteriovorus phosphoglucose isomerase reveal novel rigidity in the active site of a selected subset of enzymes upon substrate binding.

Meek, R. W.; Cadby, I. T.; Lovering, A. L.

10.1101/2021.03.26.437203 — biochemistry — Posted on 2021-03-26

815 Cross-linking/Mass Spectrometry Combined with Ion Mobility on a timsTOF Pro Instrument for Structural Proteomics

Ihling, C. H.; Piersimoni, L.; Kipping, M.; Sinz, A.

10.1101/2021.03.26.437136 — biochemistry — Posted on 2021-03-26

816 Hyperbolic disc embedding of functional human brain connectomes using resting state fMRI

Whi, W.; Ha, S.; Kang, H.; Lee, D. S.

10.1101/2021.03.25.436730 — neuroscience — Posted on 2021-03-26

817 Positive selection on mitochondria may eliminate heritable microbes from arthropod populations.

Fenton, A.; Camus, F.; Hurst, G. D. D.

10.1101/2021.03.26.437186 — evolutionary biology — Posted on 2021-03-26

818 Evolutionary differences in the ACE2 reveals the molecular origins of COVID-19 susceptibility

Cheng, R. R.; Dodero-Rojas, E.; Di Pierro, M.; Onuchic, J. N.

10.1101/2021.03.25.437113 — biophysics — Posted on 2021-03-26

819 Molecular roadmap of the healthy stress response in the mouse hippocampus

von Ziegler, L. M.; Floriou-Servou, A.; Waag, R.; Das Gupta, R. R.; Sturman, O.; Gapp, K.; Maat, C. A.; Kockmann, T.; Lin, H.-Y.; Duss, S. N.; Privitera, M.; Hinte, L.; von Meyer, F.; Zeilhofer, H. U.; Germain, P.-L.; Bohacek, J.

10.1101/2021.03.26.436970 — neuroscience — Posted on 2021-03-26

820 ANALYSIS OF CHD-7 DEFECTIVE DAUER NEMATODES IMPLICATES COLLAGEN MISREGULATION IN CHARGE SYNDROME FEATURES.

Jofre, D. M.; Hoffman, D.; Cervino, A.; Grundy, M.; Yun, S.; Gandhi Amrit, F. R.; Stolz, D. B.; Salvatore, E.; Rossi, F. A.; Ghazi, A.; Cirio, M. C.; Yanowitz, J. L.; Hochbaum, D.

10.1101/2021.03.26.437191 — genetics — Posted on 2021-03-26

821 Shank3 mutations impair electrical synapse scaffolding and transmission in mouse brain

Lautz, J.; Zhu, Z.; Speed, H.; Smith, S. E. P.; Welsh, J. P.

10.1101/2021.03.25.437056 — neuroscience — Posted on 2021-03-26

822 Massively parallel, computationally-guided design of a pro-enzyme

Yachnin, B. J.; Azouz, L. R.; White, R. E.; Minetti, C. A. S. A.; Remeta, D. P.; Tan, V. M.; Drake, J. M.; Khare, S. D.

10.1101/2021.03.25.437042 — biophysics — Posted on 2021-03-26

823 Structures of TRPM5 channel elucidate mechanism of activation and inhibition

Lu, W.; Du, J.; Ruan, Z.; Haley, E.; Orozco, I.; Roth, R.; Sabat, M.; Myers, R.

10.1101/2021.03.25.437100 — biophysics — Posted on 2021-03-26

824 Snapshots of actin and tubulin folding inside the TRiC chaperonin

Kelly, J. J.; Tranter, D.; Pardon, E.; Chi, G.; Kramer, H.; Knee, K.; Janz, J.; Steyaert, J.; Bulawa, C.; Paavilainen, V.; Huiskonen, J.; Yue, W.

10.1101/2021.03.26.436673 — biochemistry — Posted on 2021-03-26

825 Gene-gene relationships in an Escherichia coli accessory genome are linked to function and mobility

Hall, R. J.; Whelan, F. J.; Cummins, E. A.; Connor, C.; McNally, A.; McInerney, J. O.

10.1101/2021.03.26.437181 — evolutionary biology — Posted on 2021-03-26

826 ACE2 protein expression within isogenic cell lines is heterogeneous and associated with distinct transcriptomes

Sherman, E. J.; Emmer, B.

10.1101/2021.03.26.437218 — microbiology — Posted on 2021-03-26

827 A robust SARS-CoV-2 replication model in primary human epithelial cells at the air liquid interface to assess antiviral agents

Do, T. N. D.; Chatterjee, A. K.; Gallay, P. A.; Bobardt, M. D.; Vangeel, L.; De Jonghe, S.; Neyts, J.; Jochmans, D.

10.1101/2021.03.25.436907 — microbiology — Posted on 2021-03-26

828 Rapid SARS-CoV-2 Adaptation to Available Cellular Proteases

Chaudhry, M. Z.; Eschke, K.; Hoffmann, M.; Grashoff, M.; Abassi, L.; Kim, Y.; Brunotte, L.; Ludwig, S.; Kroeger, A.; Klawonn, F.; Pöhlmann, S.; Cicin-Sain, L.

10.1101/2020.08.10.241414 — microbiology — Posted on 2021-03-26

829 Genetic Modification to Design a Stable Yeast-expressed Recombinant SARS-CoV-2 Receptor Binding Domain as a COVID-19 Vaccine Candidate

Chen, W.-H.; Wei, J.; Kundu, R. T.; Adhikari, R.; Liu, Z.; Lee, J.; Versteeg, L.; Poveda, C.; Keegan, B.; Villar, M. J.; de Araujo Leao, A. C.; Altieri Rivera, J.; Gillespie, P. M.; Pollet, J.; Strych, U.; Zhan, B.; Hotez, P. J.; Bottazzi, M. E.

10.1101/2020.11.09.373449 — immunology — Posted on 2021-03-26

830 The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection

Sandoval, D. R.; Mandel Clausen, T.; Nora, C.; Magida, J. A.; Cribbs, A. P.; Denardo, A.; Clark, A. E.; Garretson, A. F.; Coker, J. K. C.; Narayanan, A.; Majowicz, S. A.; Philpott, M.; Johansson, C.; Dunford, J. E.; Spliid, C. B.; Golden, G. J.; Payne, N. C.; Tye, M. A.; Nowell, C. J.; Griffis, E. R.; Piermatteo, A.; Grunddal, K. V.; Alle, T.; Hauser, B. M.; Feldman, J.; Caradonna, T. M.; Pu, Y.; Yin, X.; McVicar, R. N.; Kwong, E. M.; Tsimikas, S.; Schmidt, A. G.; Ballatore, C.; Zengler, K.; Chanda, S. K.; Weiss, R. J.; Downes, M.; Evans, R. M.; Croker, B. A.; Leibel, S. L.; Jose, J.; Mazitsch

10.1101/2021.03.22.436522 — microbiology — Posted on 2021-03-26

831 Complete Protection of Nasal and Lung Airways Against SARS-CoV-2 Challenge by Antibody Plus Th1 Dominant N- and S-Specific T-Cell Responses to Subcutaneous Prime and Thermally-Stable Oral Boost Bivalent hAd5 Vaccination in an NHP Study

Gabitzsch, E.; Safrit, J. T.; Verma, M.; Rice, A.; Sieling, P.; Zakin, L.; Shin, A.; Morimoto, B.; Adisetiyo, H.; Wong, R.; Bezawada, A.; Dinkins, K.; Balint, J.; Peykov, V.; Garban, H.; Liu, P.; Bone, P.; Bacon, A.; Drew, J.; Sanford, D. C.; Spilman, P.; Sender, L.; Rabizadeh, S.; Niazi, K.; Soon-Shiong, P.

10.1101/2020.12.08.416297 — immunology — Posted on 2021-03-26

832 The Dual-Antigen Ad5 COVID-19 Vaccine Delivered as an Intranasal Plus Subcutaneous Prime Elicits Th1 Dominant T-Cell and Humoral Responses in CD-1 Mice

Rice, A.; Verma, M.; Shin, A.; Zakin, L.; Sieling, P.; Tanaka, S.; Balint, J.; Dinkins, K.; Adisetiyo, H.; Morimoto, B.; Higashide, W.; Taft, J.; Patel, R. S.; Buta, S.; Martin-Fernandez, M.; Bogunovic, D.; Spilman, P. R.; Gabitzsch, E. R.; Safrit, J. T.; Rabizadeh, S.; Niazi, K.; Soon-Shiong, P.

10.1101/2021.03.22.436476 — immunology — Posted on 2021-03-26

833 A multi-data based quantitative model for neurovascular coupling in the brain.

Sten, S.; Podeus, H.; Sundqvist, N.; Elinder, F.; Engström, M.; Cedersund, G.

10.1101/2021.03.25.437053 — systems biology — Posted on 2021-03-26

834 An atlas of inter- and intra-tumor heterogeneityof apoptosis competency in colorectal cancertissue at single cell resolution

Lindner, A. U.; Salvucci, M.; MCDonough, E.; Cho, S.; Stachtea, X.; O'Connell, E. P.; Corwin, A. D.; Santamaria-Pang, A.; Carberry, S.; Fichtner, M.; Van Schaeybroeck, S.; Laurent-Puig, P.; Burke, J. P.; McNamara, D.; Lawler, M.; Sood, A.; Graf, J. F.; Morrison (Rehm), M.; Dunne, P.; Longley, D.; Ginty, F.; Prehn, J. H.

10.1101/2021.03.19.436184 — cancer biology — Posted on 2021-03-26

835 ORT: A workflow linking genome-scale metabolic models with reactive transport codes

Rubinstein, R. L.; Borton, M. A.; Zhou, H.; Shaffer, M.; Hoyt, D. W.; Stegen, J.; Henry, C. S.; Wrighton, K. C.; Versteeg, R.

10.1101/2021.03.02.433463 — bioinformatics — Posted on 2021-03-26

836 GRAMMAR-Lambda: An Extreme Simplification for Genome-wide Mixed Model Association Analysis

Yang, R.; Gao, J.; Song, Y.; Hao, Z.; Xu, P.

10.1101/2021.03.10.434574 — bioinformatics — Posted on 2021-03-26

837 MultiMAP: Dimensionality Reduction and Integration of Multimodal Data

Jain, M. S.; Polanski, K.; Dominguez Conde, C.; Chen, X.; Park, J.; Mamanova, L.; Knights, A.; Botting, R.; Stephenson, E.; Haniffa, M.; Lamacraft, A.; Efremova, M.; Teichmann, S.

10.1101/2021.02.16.431421 — bioinformatics — Posted on 2021-03-26

838 Predicting transmembrane protein-protein complexes: TransINT, a novel computational approach

Khazen, G.; Gyulkhandanian, A.; Issa, T.; Maroun, R. C.

10.1101/871590 — bioinformatics — Posted on 2021-03-26

839 The fish pathogen Aliivibrio salmonicida LFI1238 can degrade and metabolize chitin despite major gene loss in the chitinolytic pathway

Skane, A.; Minniti, G.; Loose, J. S. M.; Mekasha, S.; Bissaro, B.; Mathiesen, G.; Arntzen, M. O.; Vaaje-Kolstad, G.

10.1101/2021.03.24.436902 — biochemistry — Posted on 2021-03-26

840 Testing for parallel genomic and epigenomic footprints of adaptation to urban life in a passerine bird

Caizergues, A. E.; Le Luyer, J.; Gregoire, A.; Szulkin, M.; Senar, J. C.; Charmantier, A.; Perrier, C.

10.1101/2021.02.10.430452 — genomics — Posted on 2021-03-26

841 Characterizing nucleotide variation and expansion dynamics in human-specific variable number tandem repeats

Course, M. M.; Sulovari, A.; Gudsnuk, K.; Eichler, E. E.; Valdmanis, P. N.

10.1101/2021.03.25.437092 — genomics — Posted on 2021-03-26

842 Cold adaptation drives population genomic divergence in the ecological specialist, Drosophila montana

Wiberg, R. A. W.; Tyukmaeva, V.; Hoikkala, A.; Ritchie, M. G.; Kankare, M.

10.1101/2020.04.20.050450 — evolutionary biology — Posted on 2021-03-26

843 Water yield modelling, sensitivity analysis and validation: a study for Portugal

Almeida, B.; Cabral, P.

10.1101/2021.03.20.433030 — ecology — Posted on 2021-03-26

844 Modulation of fatty acid elongation sustains sexually dimorphic hydrocarbons and female attractiveness in Blattella germanica (L.)

Pei, X.-J.; Fan, Y.-L.; Bai, Y.; Bai, T.-T.; Schal, C.; Zhang, Z.-F.; Chen, N.; Li, S.; Liu, T.-X.

10.1101/2021.03.04.434003 — ecology — Posted on 2021-03-26

845 Auto-inhibition of Cnn binding to γ-TuRCs prevents ectopic microtubule nucleation and cell division defects

Tovey, C. A.; Tsuji, C.; Egerton, A.; Bernard, F.; Guichet, A.; de la Roche, M. A.; Conduit, P. T.

10.1101/2020.10.05.326587 — cell biology — Posted on 2021-03-26

846 Disruption of origin chromatin structure by helicase activation in the absence of DNA replication

Hoffman, R. A.; MacAlpine, D. M.

10.1101/2021.03.17.435814 — molecular biology — Posted on 2021-03-26

847 A cis-RNA-mediated expression regulation of the tet(M) resistance gene in Enterococcus faecium

Le Neindre, K.; Dejoies, L.; Reissier, S.; Felden, B.; Cattoir, V.

10.1101/2021.03.24.436905 — microbiology — Posted on 2021-03-26

848 Postural perturbation induced by electrical stimulation; A new approach to examine the mechanism of falling

Tahayori, B.; Tahayori, B.; Mehdizade, A.; Koceja, D. M.

10.1101/2021.03.25.437084 — neuroscience — Posted on 2021-03-26

849 Parallel and recurrent cascade models as a unifying force for understanding sub-cellular computation

Harkin, E. F.; Shen, P. R.; Richards, B. A.; Naud, R.

10.1101/2021.03.25.437091 — neuroscience — Posted on 2021-03-26

850 A reduction methodology for fluctuation driven population dynamics

Goldobin, D.; di Volo, M.; Torcini, A.

10.1101/2021.01.28.428565 — neuroscience — Posted on 2021-03-26

851 Electrophysiological and Transcriptomic Features Reveal a Circular Taxonomy of Cortical Neurons

Rodriguez-Collado, A.; Rueda, C.

10.1101/2021.03.24.436849 — neuroscience — Posted on 2021-03-26

852 Interoception of breathing and its relationship with anxiety

Harrison, O. K.; Nanz, L.; Marino, S.; Luechinger, R.; Hennel, F.; Hess, A. J.; Fraessle, S. K.; Iglesias, S.; Vinckier, F.; Petzschner, F. H.; Harrison, S. J.; Stephan, K. E.

10.1101/2021.03.24.436881 — neuroscience — Posted on 2021-03-26

853 Collagen Deposition in Diabetic Kidney Disease Boosts Intercellular Signaling: A Mathematical Model

Thomas, H. Y.; Ford Versypt, A. N.

10.1101/2021.03.25.437068 — systems biology — Posted on 2021-03-26

854 Cinnamon bark extract suppresses metastatic dissemination of cancer cells through inhibition of glycolytic metabolism

Konno, Y.; Maruyama, A.; Tomita, M.; Makinoshima, H.; Nakayama, J.

10.1101/2021.03.25.437098 — pharmacology and toxicology — Posted on 2021-03-26

855 High-throughput characterization of 309 photocrosslinker-bearing ASIC1a variants maps residues critical for channel function and pharmacology

Braun, N.; Friis, S.; Ihling, C.; Sinz, A.; Andersen, J.; Pless, S. A.

10.1101/2020.11.24.392498 — biophysics — Posted on 2021-03-26

856 scAmpi - A versatile pipeline for single-cell RNA-seq analysis from basics to clinics

Bertolini, A.; Prummer, M.; Tuncel, M. A.; Menzel, U.; Rosano-Gonzalez, M. L.; Kuipers, J.; Stekhoven, D. J.; Tumor Profiler consortium, ; Beerenwinkel, N.; Singer, F.

10.1101/2021.03.25.437054 — bioinformatics — Posted on 2021-03-26

857 A multitask transfer learning framework for novel virus-human protein interactions

Dong, T. N.; Khosla, M.

10.1101/2021.03.25.437037 — bioinformatics — Posted on 2021-03-26

858 Cytostatic hypothermia and its impact on glioblastoma and survival

Enam, S. F.; Kilic, C. Y.; Huang, J.; Kang, B. J.; Chen, R.; Tribble, C. S.; Betancur, M. I.; Ilich, E.; Blocker, S. J.; Owen, S.; Lyon, J. G.; Bellamkonda, R. V.

10.1101/2021.03.25.436870 — bioengineering — Posted on 2021-03-26

859 CG2AT2: An Enhanced Fragment-based approach for Serial Multi-scale Molecular Dynamics simulations

Vickery, O. N.; Stansfeld, P. J.

10.1101/2021.03.25.437005 — biochemistry — Posted on 2021-03-26

860 Genome-wide identification of Arabidopsis non-AUG-initiated upstream ORFs with evolutionarily conserved regulatory sequences that control protein expression levels

Hiragori, Y.; Takahashi, H.; Hayashi, N.; Sasaki, S.; Nakao, K.; Motomura, T.; Yamashita, Y.; Naito, S.; Onouchi, H.

10.1101/2021.03.25.436978 — genomics — Posted on 2021-03-26

861 Antiviral Antibody Epitope Selection is a Heritable Trait

Venkataraman, T.; Valencia, C.; Mangino, M.; Morgenlander, W.; Clipman, S. J.; Liechti, T.; Valencia, A.; Christofidou, P.; Spector, T. D.; Roederer, M.; Duggal, P.; Larman, H. B.

10.1101/2021.03.25.436790 — genetics — Posted on 2021-03-26

862 Demonstration of local adaptation of maize landraces by reciprocal transplantation

Janzen, G. M.; Aguilar-Rangel, M. R.; Cintora-Martinez, C.; Blöcher-Juarez, K. A.; Gonzalez-Segovia, E.; Studer, A. J.; Runcie, D. E.; Flint-Garcia, S. A.; Rellan-Alvarez, R.; Sawers, R. J. H.; Hufford, M. B.

10.1101/2021.03.25.437076 — evolutionary biology — Posted on 2021-03-26

863 Quantifying diversity, connectivity, and environmental resistance in dendritic ecological networks

Chafin, T. K.; Mussmann, S. M.; Douglas, M. R.; Douglas, M. E.

10.1101/2021.03.25.437078 — ecology — Posted on 2021-03-26

864 Symbiodiniaceae conduct under natural bleaching stress during advanced gametogenesis stages of the mesophotic coral Alveopora allingi

Eyal, G.; Eyal-Shaham, L.; Loya, Y.

10.1101/2021.03.25.437087 — ecology — Posted on 2021-03-26

865 Conserved hormonal and molecular mechanisms underlying behavioural maturation in open- and cavity-nesting honey bees

Unnikrishnan, S.; Shah, A.; Bais, D.; Suryanarayanan, A.; Brockmann, A.

10.1101/2021.03.25.436783 — molecular biology — Posted on 2021-03-26

866 Dual TCR-alpha expression on MAIT cells as a potential confounder of TCR interpretation

Suliman, S.; Kjer-Nielsen, L.; Iwany, S.; Lopez, K.; Loh, L.; Kedzierska, K.; Ocampo, T. A.; Corbett, A.; McCluskey, J.; Rossjohn, J.; Leon, S.; Calderon, R.; Lecca, L.; Murray, M. B.; Moody, B.; Van Rhijn, I.

10.1101/2021.03.25.436871 — immunology — Posted on 2021-03-26

867 Somatic junctions connect microglia and developing neurons

Cserep, C.; Schwarcz, A. D.; Posfai, B.; Laszlo, Z. I.; Kellermayer, A.; Nyerges, M.; Lele, Z.; Katona, I.; Denes, A.

10.1101/2021.03.25.436920 — neuroscience — Posted on 2021-03-26

868 A pipelining mechanism supporting previewing during visual exploration and reading

Jensen, O.; Pan, Y.; Frisson, S.; Wang, L.

10.1101/2021.03.25.436919 — neuroscience — Posted on 2021-03-26

869 Low grade inflammation in the epileptic hippocampus contrasts with explosive inflammation occurring in the acute phase following status epilepticus in rats: translation to patients with epilepsy

Gasmi, N.; Navarro, F. P.; Ogier, M.; Belmeguenaï, A.; Lieutaud, T.; Georges, B.; Bodennec, J.; Guenot, M.; Streichenberger, N.; Ryvlin, P.; Rheims, S.; Bezin, L.

10.1101/2021.03.25.436701 — neuroscience — Posted on 2021-03-26

870 Temporal attention selectively enhances target features

Ramirez, L. D.; Foster, J. J.; Ling, S.

10.1101/2021.03.25.437071 — neuroscience — Posted on 2021-03-26

871 Neural dynamics of parametrically modulated human mechanical pain determined using whole-brain quantitative perfusion imaging.

Segerdahl, A. R.; Kong, Y.; Ho, I.; Tracey, I.

10.1101/2021.03.25.436356 — neuroscience — Posted on 2021-03-26

872 Dynamic distortion of the orientation representational space after learning in the mouse primary visual cortex

Corbo, J.; McClure, J. P.; Erkat, O. B.; Polack, P.-O.

10.1101/2021.03.25.437032 — neuroscience — Posted on 2021-03-26

873 Interactions between Diameter, Myelination and the Na/K pump Affect Axonal Resilience to High Frequency Spiking

Zang, Y.; Marder, E.

10.1101/2021.03.25.437049 — neuroscience — Posted on 2021-03-26

874 Synaptic signaling networks encode experience by assuming stimulus-specific and brain-region-specific states

Lautz, J. D.; Tsegay, K. B.; Zhu, Z.; Welsh, J. P.; Gniffke, E. P.; Smith, S. E. P.

10.1101/2021.03.25.437050 — neuroscience — Posted on 2021-03-26

875 DNA methylation and demethylation underlie the sex difference in estrogen receptor alpha in the arcuate nucleus

Cortes, L. R.; Cisternas, C. D.; Cabahug, I. N.; Mason, D. R.; Ramlall, E. K.; Castillo-Ruiz, A. R.; Forger, N.

10.1101/2021.03.25.437030 — neuroscience — Posted on 2021-03-26

876 Multi-centre, multi-vendor 7 Tesla fMRI reproducibility of hand digit representation in the human somatosensory cortex

Driver, I. D.

10.1101/2021.03.25.437006 — neuroscience — Posted on 2021-03-26

877 Retinal waves but not visual experience are required for development of retinal direction selectivity maps

Tiriac, A.; Bistrong, K.; Feller, M.

10.1101/2021.03.25.437067 — neuroscience — Posted on 2021-03-26

878 Brain endothelial cell tissue-nonspecific alkaline phosphatase (TNAP) activity promotes maintenance of barrier integrity via the ROCK pathway

Nwafor, D. C.; Brichacek, A. L.; Wang, W.; Bidwai, N.; Lilly, C. L.; Millan, J. L.; Brown, C. M.

10.1101/2021.03.25.437097 — neuroscience — Posted on 2021-03-26

879 Role of protein degradation in growth laws

Calabrese, L.; Grilli, J.; Osella, M.; Kempes, C. P.; Cosentino Lagomarsino, M.; Ciandrini, L.

10.1101/2021.03.25.436692 — systems biology — Posted on 2021-03-26

880 Mining signaling flow to interpret mechanisms of synergy of drug combinations using deep graph neural networks

Zhang, H.; Chen, Y.; Payne, P. R.; Li, F.

10.1101/2021.03.25.437003 — systems biology — Posted on 2021-03-26

881 Sysrev: A FAIR Platform For Data Curation And Systematic Evidence Review

Bozada, T.; Borden, J.; Del Cid, M.; Malinowski, J.; Luechtefeld, T.

10.1101/2021.03.24.436697 — scientific communication and education — Posted on 2021-03-26

882 Performance of generalist hemiparasitic Euphrasia across a phylogenetically diverse host spectrum

Brown, M.; Moore, P.; Twyford, A. D.

10.1101/2021.03.25.436816 — plant biology — Posted on 2021-03-26

883 Exploitation of the genetic variability in the genotype of Egyptian Wheat by studding Molecular Markers, Molecular Docking and Nano Composites. Regulation of leaf and stem rust

Abou-Zeid, M. A.; Reyad, N. E. H. A.; Omar, H. S.; Shamkh, I. M.

10.1101/2021.03.18.436051 — plant biology — Posted on 2021-03-26

884 DrugComb update: a more comprehensive drug sensitivity data repository and analysis portal

Zheng, S.; Aldahdooh, J.; Shadbahr, T.; Wang, Y.; Aldahdooh, D.; Bao, J.; Wang, W.; Tang, J.

10.1101/2021.03.25.436916 — pharmacology and toxicology — Posted on 2021-03-26

885 Genomic Alterations and Possible Druggable Mutations in Carcinoma of Unknown Primary (CUP)

Aboulkheyr Es, H.; Mahdizadeh, H.; Hedayati Asl, A. A.; Totonchi, M.

10.1101/2021.03.25.436921 — cancer biology — Posted on 2021-03-26

886 Discoidin domain receptor 2 drives melanoma drug resistance through AXL-dependent phenotype switching

Sala, M.; Allain, N.; Jabouille, A.; Henriet, E.; Abou-Ammoud, A.; Uguen, A.; Di-Tommaso, S.; Cyril, D.; Raymond, A.-A.; Dupuy, J.-W.; Gerard, E.; Dugot-Senant, N.; Rousseau, B.; Merlio, J.-P.; Pham-Ledart, A.; Vergier, B.; Moreau, V.; Saltel, F.

10.1101/857904 — cancer biology — Posted on 2021-03-26

887 Integrating diverse data sources to predict disease risk in dairy cattle

Lasser, J.; Matzhold, C.; Egger-Danner, C.; Fuerst-Waltl, B.; Steininger, F.; Wittek, T.; Klimek, P.

10.1101/2021.03.25.436798 — bioinformatics — Posted on 2021-03-26

888 Intra- and inter-specific density dependence of body condition, growth, and habitat temperature in chub mackerel (Scomber japonicus)

Kamimura, Y.; Taga, M.; Yukami, R.; Watanabe, C.; Furuichi, S.

10.1101/2021.03.25.436928 — ecology — Posted on 2021-03-26

889 Thermal Fogging with Disinfectant Didecyl Dimethyl Ammonium Bromide Effectively Kills A Coronavirus, An Influenza Virus and Two Indicator Bacteria in Subzero Cold-Chain Environment

Hu, Q.; Ma, P.; Hong, J.; Wang, Y.; Huang, D.; Tan, Y.; Yu, Z.

10.1101/2021.03.25.436894 — molecular biology — Posted on 2021-03-26

890 α2δ-2 is Required for Functional Postsynaptic Calcium Channel Nanodomain Signaling

Beeson, K.; Westbrook, G.; Schnell, E.

10.1101/2021.03.25.437080 — neuroscience — Posted on 2021-03-26

891 Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza

Ohno, A.; Maita, N.; Tabata, T.; Nagano, H.; Arita, K.; Ariyoshi, M.; Uchida, T.; Nakao, R.; Ulla, A.; Sugiura, K.; Kishimoto, K.; Teshima-Kondo, S.; Okumura, Y.; Nikawa, T.

10.1101/2020.06.12.149229 — biophysics — Posted on 2021-03-26

892 Validation of binary non-targeted approaches: mathematical framework and experimental designs

Uhlig, S.; Nichani, K.; Stoyke, M.; Gowik, P.

10.1101/2021.01.19.427235 — bioinformatics — Posted on 2021-03-26

893 Src activates retrograde membrane traffic through phosphorylation of GBF1

Chia, J.; Wang, S.-C.; Wee, S.; Gill, D. J.; Tay, F.; Kannan, S.; Verma, C. S.; Gunaratne, J.; Bard, F.

10.1101/2020.08.02.233353 — cell biology — Posted on 2021-03-26

894 Efficient high-resolution TMS mapping of the human motor cortex by nonlinear regression

Numssen, O.; Zier, A.-L.; Thielscher, A.; Hartwigsen, G.; Knosche, T.; Weise, K.

10.1101/2021.03.11.434996 — neuroscience — Posted on 2021-03-26

895 Neural speech tracking shifts from the syllabic to the modulation rate of speech as intelligibility decreases

Schmidt, F.; Chen, Y.-P.; Keitel, A.; Roesch, S.; Hannemann, R.; Serman, M.; Hauswald, A.; Weisz, N.

10.1101/2021.03.25.437033 — neuroscience — Posted on 2021-03-26

896 Synergy between vesicular and non-vesicular gliotransmission regulates synaptic plasticity and working memory

Lalo, U.; Rasooli-Nejad, S.; Bogdanov, A.; More, L.; Koh, W.; Muller, J.; Wall, M.; Lee, C. J.; Pankratov, Y.

10.1101/2021.03.25.437028 — neuroscience — Posted on 2021-03-26

897 Purkinje cell outputs selectively inhibit a subset of unipolar brush cells in the input layer of the cerebellar cortex

Guo, C.; Rudolph, S.; Neuwirth, M. E.; Regehr, W. G.

10.1101/2021.03.25.437031 — neuroscience — Posted on 2021-03-26

898 Structural insights into GlcNAc-1-phosphotransferase that directs lysosomal protein transport

Du, S.; Wang, G.; Zhang, Z.; Ma, C.; Gao, N.; Xiao, J.

10.1101/2021.03.25.436948 — biochemistry — Posted on 2021-03-25

899 Molecular Dynamics Study on the Effects of Charged Amino Acid Distribution Under low pH Condition to the Unfolding of Hen Egg White Lysozyme and Formation of Beta Strands.

Sutthibutpong, T.; Asanithi, P.; Alam, I.; Zein, H. F.

10.1101/2021.03.25.436950 — biophysics — Posted on 2021-03-25

900 A robust, semi-automated approach for counting cementum increments imaged with X-ray computed tomography

Newham, E.; Gill, P. G.; Robson Brown, K.; Gostling, N. J.; Corfe, I. J.; Schneider, P.

10.1101/2021.03.25.436951 — ecology — Posted on 2021-03-25

901 Ex vivo delivery of regulatory T cells for control of alloimmune priming in the donor lung

Miyamoto, E.; Takahagi, A.; Ohsumi, A.; Martinu, T.; Hwang, D.; Boonstra, K.; Joe, B.; Juan Umana, M.; Bei, K.; Vosoughi, D.; Liu, M.; Cypel, M.; Keshavjee, S.; Juvet, S. C.

10.1101/2021.02.07.430098 — immunology — Posted on 2021-03-25

902 Fuzzy-Discernibility Matrix-based Efficient Feature Selection Techniques for Improved Motor-Imagery EEG Signal Classification

Chatterjee, R.; Sanyal, D. K.; Chatterjee, A.

10.1101/2021.03.24.436722 — neuroscience — Posted on 2021-03-25

903 Systematics and phylogeography of the Brazilian Atlantic Forest endemic harvestmen Neosadocus Mello-Leitao, 1926 (Arachnida: Opiliones: Gonyleptidae)

Castro Pereira, D.; Peres, E. A.; Pinto-da-Rocha, R.

10.1101/2021.03.25.436954 — zoology — Posted on 2021-03-25

904 Effective spatio-temporal regimes for wound treatment by way of macrophage polarization: A mathematical model

Zlobina, K.; Xue, J.; Gomez, M.

10.1101/2021.03.25.436953 — systems biology — Posted on 2021-03-25

905 Pyrethroid and metal residues in different coffee bean preparing processes and their human health risk assessments via consumption

Tanhan, P.; Khunlert, P.; Poapolathep, A.; Poapolathep, S.; Imsilp, K.

10.1101/2021.03.25.436952 — pharmacology and toxicology — Posted on 2021-03-25

906 A silencer repressing redundant enhancer activities revealed by deleting endogenous cis-regulatory element of ebony in Drosophila melanogaster

Akiyama, N.; Sato, S.; Tanaka, K. M.; Sakai, T.; Takahashi, A.

10.1101/2021.03.25.436947 — genetics — Posted on 2021-03-25

907 Tissue-specific versus pleiotropic enhancers within the bric-a-brac tandem gene duplicates display differential regulatory activity and evolutionary conservation

BOURBON, H.-M. G.; Benetah, M.; Guillou, E.; MOJICA VAZQUEZ, L. H.; BAANANNOU, A.; BERNAT - FABRE, S.; LOUBIERES, V.; BANTIGNIES, F.; CAVALLI, G.; BOUBE, M.

10.1101/2021.03.25.436949 — genetics — Posted on 2021-03-25

908 Acute myeloid leukemia cells are targeted by the naturally occurring CXCR4 antagonist EPI-X4

Kaiser, L. M.; Harms, M.; Sauter, D.; Rawat, V. P. S.; Glitscher, M.; Gross, R.; Hildt, E.; Muench, J.; Buske, C.

10.1101/2021.03.11.434944 — cancer biology — Posted on 2021-03-25

909 Optimized cryo-EM data acquisition workflow by sample thickness determination

Rheinberger, J.; Oostergetel, G.; Resch, G. P.; Paulino, C.

10.1101/2020.12.01.392100 — biophysics — Posted on 2021-03-25

910 Integrin α5β1 nano-presentation regulates collective keratinocyte migration independent of substrate rigidity

Di Russo, J.; Young, J. L.; Wegner, J. W. R.; Steins, T.; Kessler, H.; Spatz, J. P.

10.1101/2021.03.08.434437 — biophysics — Posted on 2021-03-25

911 Unlimited cooperativity of Betatectivirus SSB, a novel DNA binding protein related to an atypical group of SSBs from protein-primed replicating bacterial viruses

Lechuga, A.; Kazlauskas, D.; Salas, M.; Redrejo Rodriguez, M.

10.1101/2021.03.25.437074 — biochemistry — Posted on 2021-03-25

912 A UVB-responsive common variant at chr7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor gene (AHR)

Xu, M.; Mehl, L.; Zhang, T.; Thakur, R.; Sowards, H.; Myers, T.; Jessop, L.; Chesi, A.; Johnson, M. E.; Wells, A. D.; Michael, H. T.; Bunda, P.; Jones, K.; Higson, H.; Hennessey, R. C.; Jermusyk, A.; Kovacs, M. A.; Landi, M. T.; Iles, M. M.; Goldstein, A. M.; Melanoma Meta-Analysis Consortium, ; Choi, J.; Chanock, S. J.; Grant, S. F. A.; Chari, R.; Merlino, G.; Law, M. H.; Brown, K. M.

10.1101/2021.03.25.436649 — genetics — Posted on 2021-03-25

913 Evolved changes in DNA methylation in response to the sustained loss of parental care in the burying beetle

Mashoodh, R.; Sarkies, P.; Westoby, J.; Kilner, R. M.

10.1101/2021.03.25.436923 — evolutionary biology — Posted on 2021-03-25

914 Model-based data analysis of tissue growth in thin 3D printed scaffolds

Browning, A. P.; Maclaren, O. J.; Buenzli, P. R.; Lanaro, M.; Allenby, M. C.; Woodruff, M. A.; Simpson, M. J.

10.1101/2021.03.25.436898 — cell biology — Posted on 2021-03-25

915 Acoustic Remote Control of Bacterial Immunotherapy

Abedi, M.; Yao, M.; Mittelstein, D. R.; Bar-Zion, A.; Swift, M.; Lee-Gosselin, A.; Shapiro, M. G.

10.1101/2021.03.25.434639 — synthetic biology — Posted on 2021-03-25

916 INPP4B promotes leukemia by restricting leukemic stem cell differentiation through regulation of lysosomal functions

Woolley, J. F.; Chen, K.; Genc, G. E.; Lee, D. K. C.; Dzneladze, I.; He, R.; Gabra, M. M.; Saffi, G. T.; Son, M. H.; Schoof, E. M.; Xie, S. Z.; Kotlyar, M.; Rashid, A.; Vacher, J.; Jurisica, I.; Dick, J. E.; Botelho, R. J.; Minden, M. D.; Salmena, L.

10.1101/2021.03.25.437029 — cancer biology — Posted on 2021-03-25

917 DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas (PanNECs) and pancreatic neuroendocrine tumors (PanNETs)

Simon, T.; Riemer, P.; Detjen, K.; Di Domenico, A.; Bormann, F.; Menne, A.; Khouja, S.; Monje, N.; Childs, L. H.; Lenze, D.; Leser, U.; Jarosch, A.; Rossner, F.; Morkel, M.; Bluethgen, N.; Pavel, M.; Horst, D.; Capper, D.; Marinoni, I.; Perren, A.; Mamlouk, S.; Sers, C.

10.1101/2020.06.12.146811 — cancer biology — Posted on 2021-03-25

918 Correction of multiple-blinking artefacts in photoactivated localisation microscopy

Jensen, L. G.; Hoh, T. Y.; Williamson, D. J.; Griffie, J.; Sage, D.; Rubin-Delanchy, P.; Owen, D. M.

10.1101/2021.03.24.436128 — biophysics — Posted on 2021-03-25

919 Quantitative blood flow estimation in vivo by optical speckle image velocimetry

Qureshi, M. M.; Liu, Y.; Mac, K. D.; Kim, M.; Safi, A. M.; Chung, E.

10.1101/2021.03.25.437094 — biophysics — Posted on 2021-03-25

920 Topological Tuning of DNA Mobility in Entangled Solutions of Supercoiled Plasmids

Smrek, J.; Garamella, J.; Anderson, R.; Michieletto, D.

10.1101/2020.09.21.306092 — biophysics — Posted on 2021-03-25

921 Uncovering of Cytochrome P450 Anatomy by SecStrAnnotator

Midlik, A.; Navratilova, V.; Moturu, T. R.; Koca, J.; Svobodova, R.; Berka, K.

10.1101/2020.04.15.042531 — bioinformatics — Posted on 2021-03-25

922 Brain solute transport is more rapid in periarterial than perivenous spaces

Vinje, V.; Bakker, E. N. T. P.; Rognes, M. E.

10.1101/2021.03.23.436588 — bioengineering — Posted on 2021-03-25

923 Characterisation of FADD interactome reveals novel insights into FADD recruitment and signalling at the Death Inducing Signalling Complex (DISC)

Fox, J. L.; Dickens, L. S.; Jukes-Jones, R.; Miles, G. J.; Langlais, C.; Cain, K.; MacFarlane, M.

10.1101/2021.03.25.436271 — biochemistry — Posted on 2021-03-25

Hudson, D. M.; Archer, M.; Rai, J.; Weis, M.; Fernandes, R.; Eyre, D.

10.1101/2021.03.25.437061 — biochemistry — Posted on 2021-03-25

925 Cockayne Syndrome B protein selectively interacts and resolves intermolecular DNA G-quadruplex structures

Liano, D.; Di Antonio, M.

10.1101/2021.03.25.436565 — biochemistry — Posted on 2021-03-25

926 SINEultaneous profiling of epigenetic heterogeneity and transcriptome in single cells

Hunt, K. V.; Burnard, S. M.; Roper, E. A.; Bond, D. R.; Dun, M. D.; Verrills, N. M.; Enjeti, A. K.; Lee, H. J.

10.1101/2021.03.25.436351 — genomics — Posted on 2021-03-25

927 Transcription factor RFX7 governs a tumor suppressor network in response to p53 and stress

Coronel, L.; Riege, K.; Schwab, K.; Foerste, S.; Haeckes, D.; Semerau, L.; Bernhart, S. H.; Siebert, R.; Hoffman, S.; Fischer, M.

10.1101/2021.03.25.436917 — genomics — Posted on 2021-03-25

928 A minimal yet flexible likelihood framework to assess correlated evolution

Behdenna, A.; Godfroid, M.; Petot, P.; Pothier, J.; Nous, C.; Lambert, A.; Achaz, G.

10.1101/2020.09.04.282954 — evolutionary biology — Posted on 2021-03-25

929 Holobiont Evolution: Population Genetic Theory for the Hologenome

Roughgarden, J.

10.1101/2020.04.10.036350 — evolutionary biology — Posted on 2021-03-25

930 Predicting lifestyle and host from positive selection data and genome properties in oomycetes

Gomez-Perez, D.; Kemen, E.

10.1101/2021.01.12.426341 — evolutionary biology — Posted on 2021-03-25

931 Comparative reproductive biology of deep-sea ophiuroids inhabiting polymetallic-nodule fields in the Clarion-Clipperton Fracture Zone

Laming, S. R.; Christodoulou, M.; Arbizu, P. M.; Hilario, A.

10.1101/2021.02.06.428832 — ecology — Posted on 2021-03-25

932 Strength of interactions in the Notch gene regulatory network determine lateral inhibition patterning

Sanchez-Iranzo, H.; Halavatyi, A.; Diz-Munoz, A.

10.1101/2021.03.25.436857 — developmental biology — Posted on 2021-03-25

933 Localized phosphorylation of RNA Polymerase II by G1 cyclin-Cdk promotes cell cycle entry

Koivomagi, M.; Swaffer, M. P.; Turner, J. J.; Marinov, G. K.; Skotheim, J. M.

10.1101/2021.03.25.436872 — cell biology — Posted on 2021-03-25

934 Structural basis for HCMV Pentamer recognition by antibodies and neuropilin 2

Wrapp, D.; Ye, X.; Ku, Z.; Su, H.; Jones, H. G.; Wang, N.; Mishra, A. K.; Freed, D. C.; Li, F.; Tang, A.; Li, L.; Jaijyan, D. K.; Zhu, H.; Wang, D.; Fu, T.-M.; Zhang, N.; An, Z.; McLellan, J. S.

10.1101/2021.03.25.436804 — microbiology — Posted on 2021-03-25

935 Modelling The Effect of MUC1 on Influenza Virus Infection Kinetics and Macrophage Dynamics

Li, K.; Cao, P.; McCaw, J. M.

10.1101/2021.03.25.436891 — immunology — Posted on 2021-03-25

936 Temporal Scaling of Human Scalp-Recorded Potentials

Hassall, C. D.; Harley, J.; Kolling, N.; Hunt, L. T.

10.1101/2020.12.11.421180 — neuroscience — Posted on 2021-03-25

937 Physiology and function of PNS axons rely on glycolic metabolism in myelinating Schwann cells

DECK, M.; Van Hameren, G.; Campbell, G.; Bernard-Marissal, N.; Devaux, J.; Berthelot, J.; Lattard, A.; Medard, J.-J.; Gautier, B.; Quintana, P.; Chao De La Barca, J. M.; Reynier, P.; Lenaers, G.; Chrast, R.; Tricaud, N.

10.1101/2020.04.23.049056 — neuroscience — Posted on 2021-03-25

938 Lack of sex differences in gonadotropin-releasing hormone (GnRH) neuron potassium currents and excitability

DeFazio, R. A.; Moenter, S. M.

10.1101/2021.03.24.436851 — neuroscience — Posted on 2021-03-25

939 Variability in infants functional brain network connectivity is associated with differences in affect and behavior

Kelsey, C. M.; Farris, K.; Grossmann, T.

10.1101/2020.07.15.204271 — neuroscience — Posted on 2021-03-25

940 Reduced inhibition in depression impairs stimulus processing in human cortical microcircuits

Yao, H. K.; Guet-McCreight, A.; Mazza, F.; Moradi Chameh, H.; Prevot, T. D.; Griffiths, J.; Tripathy, S. J.; Valiante, T. A.; Sibille, E.; Hay, E.

10.1101/2021.02.17.431698 — neuroscience — Posted on 2021-03-25

941 Unilateral and Bilateral Subthalamic stimulation differently promote apathy: a translational approach

Vachez, Y.; Bahout, M.; Magnard, R.; David, P.-M.; Carcenac, C.; Robert, G.; Savasta, M.; Carnicella, S.; Vérin, M.; Boulet, S.

10.1101/2020.06.11.147116 — neuroscience — Posted on 2021-03-25

942 The von Willebrand Factor stamps Plasmatic Extracellular Vesicles from Glioblastoma Patients

Sabbagh, Q.; Andre-Gregoire, G.; Alves-Nicolau, C.; Bidere, N.; Jouglar, E.; Guevel, L.; Frenel, J.-S.; Gavard, J.

10.1101/2021.03.25.437073 — cancer biology — Posted on 2021-03-25

943 Anti-cancer properties of cannabidiol and Δ9-tetrahydrocannabinol and potential synergistic effects with gemcitabine, cisplatin and other cannabinoids in bladder cancer

Tomko, A. M.; Whynot, E. G.; Dupre, D. J.

10.1101/2021.03.25.436633 — cancer biology — Posted on 2021-03-25

944 Invasive dedifferentiated melanoma cells inhibit JAK1-STAT3-driven actomyosin contractility of human fibroblastic reticular cells of the lymph node

Rovera, C.; Berestjuk, I.; Lecacheur, M.; Diazzi, S.; Mallavialle, A.; Albrengues, J.; Gaggioli, C.; Girard, C. C.; Passeron, T.; Deckert, M.; Tartare-Deckert, S.; Prod'homme, V.

10.1101/2021.03.25.436913 — cancer biology — Posted on 2021-03-25

945 Pathway dynamics can delineate the sources of transcriptional noise in gene expression

Ham, L.; Jackson, M.; Stumpf, M. P. H.

10.1101/2020.09.30.319814 — biophysics — Posted on 2021-03-25

946 Discovery of 17 conserved structural RNAs in fungi

Gao, W.; Jones, T. A.; Rivas, E.

10.1101/2021.02.01.429235 — bioinformatics — Posted on 2021-03-25

947 Combining IP3 affinity chromatography and bioinformatics reveals a novel protein-IP3 binding site on Plasmodium falciparum MDR1 transporter

Alves, E.; Nakaya, H. I.; Guimaraes, E.; Garcia, C. R.

10.1101/2021.03.25.437059 — biochemistry — Posted on 2021-03-25

948 Activity Budget and Postural Behaviours in Orangutans on Bukit Merah Orang Utan Island for Assessing Captive Great Ape Welfare

Kamaluddin, S. N.; Matsuda, I.; Md-Zain, B. M.

10.1101/2020.12.15.422872 — animal behavior and cognition — Posted on 2021-03-25

949 Target Capture Sequencing of SARS-CoV-2 Genomes Using the ONETest Coronaviruses Plus

Zhan, S. H.; Alamouti, S. M.; Kwok, B. S.; Lee, M.-H.; Khattra, J.; Daneshpajouh, H.; Houck, H. J.; Rand, K. H.

10.1101/2021.03.25.437083 — genomics — Posted on 2021-03-25

950 Slit2 is necessary for optic axon organization in the zebrafish ventral midline

Davison, C.; Zolessi, F. R.

10.1101/2020.09.25.314062 — developmental biology — Posted on 2021-03-25

951 Regulation of oogenesis in the queen honey bee (Apis mellifera)

Aamidor, S. E.; Cardoso Junior, C. A. M.; Harianto, J.; Nowell, C. J.; Cole, L.; Oldroyd, B. P.; Ronai, I.

10.1101/2021.03.08.434480 — developmental biology — Posted on 2021-03-25

952 Scribble mutation disrupts convergent extension and apical constriction during mammalian neural tube closure

Lesko, A. C.; Keller, R.; Chen, P.; Sutherland, A.

10.1101/2020.09.18.303446 — developmental biology — Posted on 2021-03-25

953 Spatiotemporal Control of Actomyosin Contractility by MRCKβ Signaling Drives Phagocytosis

Zihni, C.; Georgiadis, T.; Ramsden, C.; Sanchez-heras, E.; Nommiste, B.; Semenyuk, O.; Bainbridge, J.; Coffey, P.; Smith, A.; Ali, R.; Balda, M.; Matter, K.

10.1101/2021.03.25.436833 — cell biology — Posted on 2021-03-25

954 Actin dependent membrane polarization reveals the mechanical nature of the neuroblast polarity cycle

LaFoya, B.; Prehoda, K.

10.1101/2021.01.15.426888 — cell biology — Posted on 2021-03-25

955 Beta-adrenergic receptor signaling regulates ER-mitochondria contacts

Lim, Y.; Cho, I.-T.; Rennke, H. G.; Cho, G.

10.1101/2020.05.11.088815 — cell biology — Posted on 2021-03-25

956 Membrane insertion of Cavin1 facilitates caveolae assembly

Liu, K.-c.; Pace, H.; Larsson, E.; Hossain, S.; Kabedev, A.; Mohan, J.; Bergstrom, C. A. S.; Schwieger, C.; Hubert, M.; Lundmark, R.

10.1101/2021.03.23.436578 — cell biology — Posted on 2021-03-25

957 The endosome is a master regulator of plasma membrane collagen fibril assembly

CHANG, J.; PICKARD, A.; GARVA, R.; Lu, Y.; Gullberg, D.; KADLER, K. E.

10.1101/2021.03.25.436925 — cell biology — Posted on 2021-03-25

958 RBFOX2 Is Critical For Maintaining Alternative Polyadenylation And Mitochondrial Health In Rat Myoblasts

Cao, J.; Verma, S. K.; Jaworski, E.; Mohan, S.; Nagasawa, C.; Rayavara, K.; Belanger, K.; Sooter, A.; Miller, S.; Holcomb, R. J.; Ji, P.; Elrod, N.; Yildirim, E.; Wagner, E. J.; Popov, V.; Garg, N. J.; Routh, A. L.; Kuyumcu-Martinez, M. N.

10.1101/2020.05.13.093013 — molecular biology — Posted on 2021-03-25

959 The Hox transcription factor Ultrabithorax binds RNA and regulates co-transcriptional splicing through an interplay with RNA polymerase II

Carnesecchi, J.; Boumpas, P.; van Nierop y Sanchez, P.; Domsch, K.; Pinto, H. D.; Borges Pinto, P.; Lohmann, I.

10.1101/2021.03.25.434787 — molecular biology — Posted on 2021-03-25

960 Parasitic nematode fatty acid- and retinol-binding proteins compromise host immunity by interfering with host lipid signaling pathways

Parks, S.; Nguyen, C.; Nasrolahi, S.; Juncaj, D.; Lu, D.; Ramaswamy, R.; Dhillon, H.; Buchman, A.; Akbari, O. S.; Yamanaka, N.; Boulanger, M. J.; Dillman, A. R.

10.1101/2021.03.25.436866 — molecular biology — Posted on 2021-03-25

961 A covariation analysis reveals elements of selectivity in quorum sensing systems

Wellington, M. S.; Cong, Q.; Schaefer, A. L.; MacLeod, E. K.; Zimenko, A.; Baker, D.; Greenberg, E. P.

10.1101/2021.03.25.437039 — microbiology — Posted on 2021-03-25

962 Computational assessment of the spike protein antigenicity reveals diversity in B cell epitopes but stability in T cell epitopes across SARS-CoV-2 variants

Ge, A.; Rioux, M.; Kelvin, A. A.

10.1101/2021.03.25.437035 — microbiology — Posted on 2021-03-25

963 Disrupting hierarchical control of nitrogen fixation enables carbon-dependent regulation of ammonia excretion in soil diazotrophs

Bueno Batista, M.; Brett, P.; Appia-Ayme, C.; Wang, Y.-P.; Dixon, R.

10.1101/2021.03.25.436926 — microbiology — Posted on 2021-03-25

964 Diversity and metagenome analysis of a hydrocarbon-degrading bacterial consortium from asphalt lakes located in Wietze, Germany

Eze, M. O.; Hose, G. C.; George, S. C.; Daniel, R.

10.1101/2021.03.25.436929 — microbiology — Posted on 2021-03-25

965 Sulforaphane exhibits in vitro and in vivo antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses

Ordonez, A. A.; Bullen, C. K.; Villabona-Rueda, A. F.; Thompson, E. A.; Turner, M. L.; Davis, S. L.; Komm, O.; Powell, J. D.; D'Alessio, F. R.; Yolken, R. H.; Jain, S. K.; Jones-Brando, L.

10.1101/2021.03.25.437060 — microbiology — Posted on 2021-03-25

966 Characterization of a glycolipid glycosyltransferase with broad substrate specificity from the marine bacterium Candidatus Pelagibacter sp. HTCC7211

Wei, T.; Zhao, C.; Quareshy, M.; Wu, N.; Huang, S.; Zhao, Y.; Yang, P.; Mao, D.; Chen, Y.

10.1101/2021.03.25.437072 — microbiology — Posted on 2021-03-25

967 Abated immune responses against recombinant hepatitis-b vaccine by chitin in mice

Joshua, P. E.; Ayogu, N. E.; Ezeorba, T. P. C.; Odimegwu, D. C.; Asomadu, R. O.; Ukachukwu, U. G.

10.1101/2021.03.25.436808 — immunology — Posted on 2021-03-25

968 Gene-experience correlation during cognitive development: Evidence from the Adolescent Brain Cognitive Development (ABCD) StudySM

Loughnan, R.; Palmer, C. E.; Thompson, W. K.; Dale, A. M.; Jernigan, T. L.; Fan, C. C.

10.1101/637512 — neuroscience — Posted on 2021-03-25

969 Uncertainty is Maintained and Used in Working Memory

Yoo, A. H.; Acerbi, L.; Ma, W. J.

10.1101/2020.10.06.328310 — neuroscience — Posted on 2021-03-25

970 Retracing Schwann cell developmental transitions in embryonic dissociated DRG/Schwann cell cocultures in mice

Sundaram, V. K.; El Jalkh, T.; Barakat, R.; Fernandez, C. J. I.; Massaad, C.; Grenier, J.

10.1101/2020.07.31.231258 — neuroscience — Posted on 2021-03-25

971 Somatostatin interneurons activated by 5-HT2A receptor suppress slow oscillations in medial entorhinal cortex

de Filippo, R.; Rost, B.; Stumpf, A.; Cooper, C.; Tukker, J.; Harms, C.; Beed, P.; Schmitz, D.

10.1101/2020.05.26.113373 — neuroscience — Posted on 2021-03-25

972 Simulating single-cell metabolism using a stochastic flux-balance analysis algorithm

Tourigny, D. S.; Goldberg, A.; Karr, J. R.

10.1101/2020.05.22.110577 — systems biology — Posted on 2021-03-25

973 Freely accessible ready to use global infrastructure for SARS-CoV-2 monitoring

Maier, W.; Bray, S.; van den Beek, M.; Bouvier, D.; Coraor, N.; Miladi, M.; Singh, B.; Rambla De Argila, J.; Baker, D.; Roach, N.; Gladman, S.; Coppens, F.; Martin, D.; Lonie, A.; Gruning, B.; Kosakovsky Pond, S.; Nekrutenko, A.

10.1101/2021.03.25.437046 — bioinformatics — Posted on 2021-03-25

974 Genomic surveillance and phylodynamic analyses reveal emergence of novel mutation and co-mutation patterns within SARS-CoV2 variants prevalent in India

Biswas, N.; Mallick, P.; Maity, S. K.; Bhowmik, D.; Mitra, A. G.; Saha, S.; Roy, A.; Chakrabarti, P.; Paul, S.; Chakrabarti, S.

10.1101/2021.03.25.436930 — genomics — Posted on 2021-03-25

975 Drying of virus-containing aerosol particles: Modelling effects of droplet origin and composition.

Jarvis, M. C.

10.1101/2021.03.25.436946 — biophysics — Posted on 2021-03-25

976 Red-shifted iLOV mutants have decreased brightness disrupting their use in live cell imaging

Wehler, P.; Oeztuerk, M. A.

10.1101/2021.03.25.436974 — biophysics — Posted on 2021-03-25

977 Lipid membranes modulate the activity of RNA through sequence-specific interactions

Czerniak, T.; Saenz, J. P.

10.1101/2021.03.25.437010 — biochemistry — Posted on 2021-03-25

978 Ovalbumin antigen-specific activation of T cell receptor closely resembles soluble antibody stimulation as revealed by BOOST phosphotyrosine proteomics

Chua, X. Y.; Salomon, A.

10.1101/2021.03.25.436968 — biochemistry — Posted on 2021-03-25

979 Can we distinguish modes of selective interactions using linkage disequilibrium?

Ragsdale, A. P.

10.1101/2021.03.25.437004 — evolutionary biology — Posted on 2021-03-25

980 Phylogenomic data reveal hard polytomies across the backbone of the large genus Solanum (Solanaceae)

Gagnon, E.; Hilgenhof, R.; Orejuela, A.; McDonnell, A.; Sablok, G.; Aubriot, X.; Giacomin, L.; Gouvêa, Y.; Bohs, L.; Dodsworth, S.; Martine, C. T.; Poczai, P.; Knapp, S.; Särkinen, T.

10.1101/2021.03.25.436973 — evolutionary biology — Posted on 2021-03-25

981 Integrated population genomic analysis and numerical simulation to estimate larval dispersal of Acanthaster cf. solaris between Ogasawara and other Japanese regions

Horoiwa, M.; Nakamura, T.; Yuasa, H.; Kajitani, R.; Ameda, Y.; Sasaki, T.; Taninaka, H.; Kikuchi, T.; Yamakita, T.; Toyoda, A.; Ito, T.; Yasuda, N.

10.1101/2021.03.25.436911 — ecology — Posted on 2021-03-25

982 Neuronal ribosomes dynamically exchange ribosomal proteins in a context-dependent manner.

Fusco, C. M.; Desch, K.; Doerrbaum, A. R.; Wang, M.; Staab, A.; Chan, I. C. W.; Vail, E.; Villeri, V.; Langer, J. D.; Schuman, E. M.

10.1101/2021.03.25.437026 — molecular biology — Posted on 2021-03-25

983 Isolation and Purification of Lipoarabinomannan from Urine of Adults with Active Tuberculosis

Cantera, J. L.; Rashid, A.; Lillis, L.; Peck, R.; Drain, P. K.; Pinter, A.; Kawasaki, M.; Moreau, E.; Boyle, D. S.

10.1101/2021.03.24.436904 — microbiology — Posted on 2021-03-25

984 Pseudomonas aeruginosa isolates defective in function of the LasR quorum sensing regulator are frequent in diverse environmental niches

Groleau, M.-C.; Taillefer, H.; Vincent, A. T.; Constant, P.; Deziel, E.

10.1101/2021.03.25.437011 — microbiology — Posted on 2021-03-25

985 Extrasynaptic GABA waves underlie epileptiform rhythms in the hippocampal network

Magloire, V.; Savtchenko, L. P.; Sylantyev, S.; Jensen, T. P.; Cole, N.; Marvin, J. S.; Looger, L. L.; Kullmann, D. M.; Walker, M. C.; Pavlov, I.; Rusakov, D. A.

10.1101/2021.03.25.437016 — neuroscience — Posted on 2021-03-25

986 Mathematical Models of Retinitis Pigmentosa: The Trophic Factor Hypothesis

Roberts, P. A.

10.1101/2021.03.25.436992 — systems biology — Posted on 2021-03-25

987 Too little, too late: transcription during imbibition of lethally aged soybean seeds is weak and delayed, but not aberrant

Fleming, M. B.; Patterson, E. L.; Walters, C.

10.1101/2021.03.25.437023 — plant biology — Posted on 2021-03-25

988 Tissue flow through pores: a computational study

Kempf, F.; Goychuk, A.; Frey, E.

10.1101/2021.03.25.436985 — biophysics — Posted on 2021-03-25

989 Adjustment of spurious correlations in co-expression measurements from RNA-Sequencing data

Hsieh, P.-H.; Lopes-Ramos, C. M.; Sandve, G. K.; Glass, K.; Kuijjer, M. L.

10.1101/2021.03.25.436972 — bioinformatics — Posted on 2021-03-25

990 Cooperation among c-subunits of FoF1-ATP synthase in rotation-coupled proton translocation

Mitome, N.; Kubo, S.; Ohta, S.; Takashima, H.; Shigefuji, Y.; Niina, T.; Takada, S.

10.1101/2021.03.25.436961 — biochemistry — Posted on 2021-03-25

991 Comparing two circular distributions: advice for effective implementation of statistical procedures in biology

Landler, L.; Ruxton, G. D.; Malkemper, E. P.

10.1101/2021.03.25.436932 — animal behavior and cognition — Posted on 2021-03-25

992 Spatiotemporal patterns in Golden-cheeked Warbler breeding habitat quality and quantity

Dreiss, L.; Sanchez-Navarro, P.; Bird, B.

10.1101/2021.03.25.436967 — ecology — Posted on 2021-03-25

993 Patterns and mechanisms underlying ecoregion delineation in North American freshwater plants

Alahuhta, J.; Garcia-Giron, J.

10.1101/2021.03.25.436944 — ecology — Posted on 2021-03-25

994 Identification of a new, Rab14-dependent, endo-lysosomal pathway

Trofimenko, E.; Homma, Y.; Fukuda, M.; Widmann, C.

10.1101/2021.03.25.436964 — cell biology — Posted on 2021-03-25

995 Cannabinoid signaling promotes the reprogramming of Muller glia into proliferating progenitor cells.

Campbell, W.; Blum, S.; Reske, A.; Hoang, T.; Blackshaw, S.; Fischer, A.

10.1101/2021.03.25.436969 — molecular biology — Posted on 2021-03-25

996 A State Space Modeling Approach to Real-Time Phase Estimation

Wodeyar, A.; Schatza, M.; Widge, A. S.; Eden, U. T.; Kramer, M. A.

10.1101/2021.03.25.437024 — neuroscience — Posted on 2021-03-25

997 Calcium-Permeable AMPA Receptor Activity and GluA1 Trafficking in the Basolateral Amygdala Regulate the Positive Reinforcing Effects of Alcohol

Faccidomo, S.; Cogan, E.; Hon, O. J.; Hoffman, J. L.; Saunders, B.; Eastman, V.; Kim, M.; Taylor, S.; McElligott, Z.; Hodge, C. W.

10.1101/2021.03.25.436994 — neuroscience — Posted on 2021-03-25

998 MEG cortical microstates: spatiotemporal characteristics, dynamic functional connectivity and stimulus-evoked responses

Tait, L.; Zhang, J.

10.1101/2021.03.25.436979 — neuroscience — Posted on 2021-03-25

999 Brain virtual histology with X-ray phase-contrast tomography Part II: 3D morphologies of amyloid-β plaques in Alzheimer's disease models

Chourrout, M.; Roux, M.; Boisvert, C.; Gislard, C.; Legland, D.; Arganda-Carreras, I.; Olivier, C.; Peyrin, F.; Boutin, H.; Rama, N.; Baron, T.; Meyronet, D.; Brun, E.; Rositi, H.; Wiart, M.; Chauveau, F.

10.1101/2021.03.25.436908 — neuroscience — Posted on 2021-03-25

1000 Synchronized Neural Activity Indexes Engagement with Spoken Stories under Acoustic Masking

Irsik, V. C.; Johnsrude, I.; Herrmann, B.

10.1101/2021.03.25.437022 — neuroscience — Posted on 2021-03-25

1001 Brain image-derived phenotypes yield insights into causal risk of psychiatric disorders using a Mendelian randomization study

Guo, J.; Yu, K.; Guo, Y.; Yao, S.; Wu, H.; Zhang, K.; Rong, Y.; Guo, M.-R.; Dong, S.-S.; Yang, T.-L.

10.1101/2021.03.25.436910 — neuroscience — Posted on 2021-03-25

1002 Respiration aligns perception with neural excitability

Kluger, D. S.; Balestrieri, E.; Busch, N. A.; Gross, J.

10.1101/2021.03.25.436938 — neuroscience — Posted on 2021-03-25

1003 A tau class Glutathione-S-Transferase (OsGSTU5) acts as a negative regulator of VirE2 interaction with T-DNA during Agrobacterium infection in rice

Tiwari, M.; Gautam, N.; Indoliya, Y.; Kidwai, M.; Mishra, A. K.; Chakrabarty, D.

10.1101/2021.03.25.436940 — plant biology — Posted on 2021-03-25

1004 Fluid Menisci and In Vitro Particle Dosimetry of Submerged Cells

Balog, S.; Rothen-Rutishauser, B.; Fink, A.

10.1101/2021.03.25.436962 — pharmacology and toxicology — Posted on 2021-03-25

1005 Bacterial cell shape control by nutrient-dependent synthesis of cell division inhibitors

Ojkic, N.; Banerjee, S.

10.1101/2021.03.25.436990 — biophysics — Posted on 2021-03-25

1006 ENNAVIA is an innovative new method which employs neural networks for antiviral and anti-coronavirus activity prediction for therapeutic peptides

Timmons, P. B.; Hewage, C. M.

10.1101/2021.03.25.436982 — bioinformatics — Posted on 2021-03-25

1007 LEVIATHAN: efficient discovery of large structural variants by leveraging long-range information from Linked-Reads data

Morisse, P.; Legeai, F.; Lemaitre, C.

10.1101/2021.03.25.437002 — bioinformatics — Posted on 2021-03-25

1008 FPM app: an open-source application for simple and intuitive Fourier ptychographic reconstruction

Rogalski, M.; Zdankowski, P.; Trusiak, M.

10.1101/2021.03.25.436959 — bioinformatics — Posted on 2021-03-25

1009 Effect of temperature and loading frequency on the performance of vertical subsurface flow constructed wetlands: Modelling study using HYDRUS

Jayswal, N.; Rodriguez, J.

10.1101/2021.03.25.436912 — bioengineering — Posted on 2021-03-25

1010 Modelling the efficacy of Neprilysin from various species in degrading different Amyloid-beta peptides: Potential application in therapeutics of Alzheimers disease

Kumar, A.

10.1101/2021.03.25.436981 — biochemistry — Posted on 2021-03-25

1011 Neurogenesis-mediated forgetting of complex paired-associates memories

Epp, J. R.; Botly, L. C.; Josselyn, S.; Frankland, P. W.

10.1101/2021.03.25.437009 — animal behavior and cognition — Posted on 2021-03-25

1012 Gene conversion facilitates the adaptive evolution of self-resistance in highly toxic newts

Gendreau, K. L.; Hornsby, A. D.; Hague, M.; McGlothlin, J. W.

10.1101/2021.03.25.437018 — evolutionary biology — Posted on 2021-03-25

1013 Lotka-Volterra equations in the presence of Mimicry

Enaganti, I.; Mishra, B.

10.1101/2021.03.25.436931 — evolutionary biology — Posted on 2021-03-25

1014 A robust SARS-CoV-2 replication model in primary human epithelial cells at the air liquid interface to assess antiviral agents

Do, T. N. D.; Chatterjee, A. K.; Gallay, P. A.; Bobardt, M. D.; Vangeel, L.; De Jonghe, S.; Neyts, J.; Jochmans, D.

10.1101/2021.03.25.436907 — microbiology — Posted on 2021-03-25

1015 The N400 ERP component reflects a learning signal during language comprehension

Hodapp, A.; Rabovsky, M.

10.1101/2021.03.25.436922 — neuroscience — Posted on 2021-03-25

1016 Autophagy promotes photomorphogenesis during seedling development in Arabidopsis in carbon limiting conditions

Wijerathna-Yapa, A.; Signorelli, S.; Fenske, R.; Ganguly, D. R.; Stroeher, E.; Li, L.; Pogson, B. J.; Duncan, O.; Millar, A. H.

10.1101/2021.03.25.437007 — plant biology — Posted on 2021-03-25

1017 Computational prediction of the effect of amino acid changes on the binding affinity between SARS-CoV-2 spike protein and the human ACE2 receptor

Chen, C.; Boorla, V. S.; Banerjee, D.; Chowdhury, R.; Cavener, V. S.; Nissly, R. H.; Gontu, A.; Boyle, N. R.; Vandegrift, K.; Nair, M. S.; Kuchipudi, S. V.; Maranas, C. D.

10.1101/2021.03.24.436885 — biophysics — Posted on 2021-03-25

1018 Unsupervised temporal consistency improvement for microscopy video segmentation with Siamese networks

Shabanov, A.; Schichler, D.; Pape, C.; Cuylen-Haering, S.; Kreshuk, A.

10.1101/2021.03.25.436993 — bioinformatics — Posted on 2021-03-25

1019 The Nestin neural enhancer is essential for normal levels of endogenous Nestin in neuroprogenitors but is not required for embryo development

Thomson, E.; Dawson, R.; H'ng, C. H.; Adikusuma, F.; Piltz, S.; Thomas, P.

10.1101/2021.03.25.436942 — developmental biology — Posted on 2021-03-25

1020 COVID-19: A need for new rather than repurposed antiviral drugs.

Kovacs, D.; Davis, C.; Cannon, P.; McFarlane, M.; Rainey, S. M.; Pinto, R.; Stewart, M. E.; Szemiel, A. M.; Taggart, A.; Kohl, A.; Marra, F.; Thomson, E. C.; Scott, J. T.

10.1101/2021.03.25.436935 — microbiology — Posted on 2021-03-25

1021 CCR2 Regulates Vaccine-Induced Mucosal T cell Memory to Influenza A Virus

Suresh, M.; Lee, W.; Kingstad-Bakke, B.; Kedl, R.; Kawaoka, Y.

10.1101/2021.03.24.436901 — immunology — Posted on 2021-03-25

1022 Efficacy of a Broadly Neutralizing SARS-CoV-2 Ferritin Nanoparticle Vaccine in Nonhuman Primates

Joyce, M. G.; King, H. A. D.; Elakhal Naouar, I.; Ahmed, A.; Peachman, K. K.; Cincotta, C. M.; Subra, C.; Chen, R. E.; Thomas, P. V.; Chen, W.-H.; Sankhala, R. S.; Hajduczki, A.; Martinez, E. J.; Peterson, C. E.; Chang, W. C.; Choe, M.; Smith, C.; Lee, P. J.; Headley, J. A.; Taddese, M. G.; Elyard, H. A.; Cook, A.; Anderson, A.; McGuckin-Wuertz, K.; Dong, M.; Swafford, I.; Case, J. B.; Currier, J. R.; Lal, K. G.; O'Connell, R. J.; Molnar, S.; Nair, M. S.; Dussupt, V.; Daye, S. P.; Zeng, X.; Barkei, E. K.; Staples, H. M.; Alfson, K.; Carrion, R.; Krebs, S. J.; Paquin-Proulx, D.; Karasavva, N.;

10.1101/2021.03.24.436523 — immunology — Posted on 2021-03-25

1023 Multiple forms of working memory emerge from synapse-astrocyte interactions

De Pitta, M.; Brunel, N.

10.1101/2021.03.25.436819 — neuroscience — Posted on 2021-03-25

1024 Identifying Brain Regions Related to Word Prediction During Listening to Japanese Speech by Combining a LSTM Language Model and MEG

Takahashi, Y.; Oseki, Y.; Sakai, H.; Makuuchi, M.; Osu, R.

10.1101/2021.03.25.436887 — neuroscience — Posted on 2021-03-25

1025 Astrocytes render memory flexible

Koh, W.; Park, M.; Chun, Y. E.; Lee, J.; Shim, H. s.; Park, M. G.; Kim, S.; Kang, H.; Oh, S.-J.; Woo, J.; Chun, H.; Lee, S.; Hong, J.; Feng, J.; Li, Y.; Ryu, H.; Cho, J.; Lee, C. J.

10.1101/2021.03.25.436945 — neuroscience — Posted on 2021-03-25

1026 Rice MEL2 regulates the timing of meiotic transition as a component of cytoplasmic RNA granules

Mimura, M.; Ono, S.; Nonomura, K.-I.

10.1101/2021.03.24.433842 — plant biology — Posted on 2021-03-25

1027 Methodological considerations when assessing mitochondrial respiration and biomarkers for mitochondrial content in human skeletal muscle

Kuang, J.; Saner, N. J.; Botella, J.; Lee, M. J.-C.; Granata, C.; Wang, Z.; Yan, X.; Li, J.; Genders, A. J.; Bishop, D. J.

10.1101/2021.03.25.436899 — physiology — Posted on 2021-03-25

1028 Healthier decisions in the cued-attribute food choice paradigm have high test-retest reliability across five task repetitions over 14 days

Barakchian, Z.; Beharelle, A. R.; Hare, T.

10.1101/2021.03.25.437001 — animal behavior and cognition — Posted on 2021-03-25

1029 A numerical framework for genetic hitchhiking in populations of variable size

Friedlander, E.; Steinruecken, M.

10.1101/2021.03.25.437048 — genetics — Posted on 2021-03-25

1030 The influence of sex, hormone status, and growth rate on dietary isotope fractionation: a case study with laboratory rats

Santollo, J.; Jones, C.; Kim, S. L.

10.1101/2021.03.25.436995 — ecology — Posted on 2021-03-25

1031 Biofilm-forming capacity of Escherichia coli isolated from cattle and beef packing plants: relation to virulence attributes, stage of processing, antimicrobial interventions, and heat tolerance

Stanford, K.; Tran, F.; Zhang, P.; Yang, X.

10.1101/2021.03.24.436903 — microbiology — Posted on 2021-03-25

1032 Convergent evolution of a novel blood-red nectar pigment in vertebrate-pollinated flowers

Roy, R.; Moreno, N.; Brockman, S. A.; Kostanecki, A.; Zambre, A.; Holl, C.; Solhaug, E. M.; Minami, A.; Snell-Rood, E.; Hampton, M.; Bee, M. A.; Chiari, Y.; Hegeman, A. D.; Carter, C.

10.1101/2021.03.24.436888 — evolutionary biology — Posted on 2021-03-25

1033 Prevalence of sustainable and unsustainable use of wild species inferred from the IUCN Red List

Marsh, S. M. E.; Hoffmann, M.; Burgess, N. D.; Brooks, T. M.; Challender, D. W. S.; Cremona, P. J.; Hilton-Taylor, C.; Lafaye de Micheaux, F.; Lichtenstein, G.; Roe, D.; Bohm, M.

10.1101/2020.11.04.367763 — ecology — Posted on 2021-03-25

1034 A species-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for preimplantation development

Modzelewski, A. J.; Shao, W.; Chen, J.; Lee, A.; Qi, X.; Noon, M.; Tjokro, K.; Sales, G.; Biton, A.; Speed, T.; Xuan, Z.; Wang, T.; Risso, D.; He, L.

10.1101/2021.03.24.436683 — developmental biology — Posted on 2021-03-25

1035 Integrated multi-omics investigations reveal the key role of synergistic microbial networks in removing plasticizer di-(2-ethylhexyl) phthalate from estuarine sediments

Wei, S. T.-S.; Chen, Y.-L.; Wu, Y.-W.; Wu, T.-Y.; Lai, Y.-L.; Wang, P.-H.; Ismail, W.; Lee, T.-H.; Chiang, Y.-R.

10.1101/2021.03.24.436900 — microbiology — Posted on 2021-03-25

1036 Virucidal and antiviral activity of astodrimer sodium against SARS-CoV-2 in vitro

Paull, J. R. A.; Heery, G. P.; Bobardt, M. D.; Castellarnau, A.; Luscombe, C. A.; Fairley, J. K.; Gallay, P. A.

10.1101/2020.08.20.260190 — microbiology — Posted on 2021-03-25

1037 Lateralized deficits in arousal processing after insula lesions: behavioral and autonomic evidence

Holtmann, O.; Franz, M.; Moenig, C.; Tenberge, J.-G.; Schlossmacher, I.; Ivanova, I.; Preul, C.; Schwindt, W.; Melzer, N.; Miltner, W.; Straube, T.

10.1101/2021.03.24.436828 — neuroscience — Posted on 2021-03-25

1038 C9ORF72 dipeptide repeat proteins disrupt formation of GEM bodies and induce aberrant accumulation of survival of motor neuron protein

Kato, Y.; Naganuma, M.; Nakagawa, I.; Onodera, K.; Okano, H.; Inoue, H.; Hattori, M.; Okada, Y.; Tsuiji, H.

10.1101/2021.03.24.436890 — neuroscience — Posted on 2021-03-25

1039 Bile salt hydrolases deplete conjugated bile acids and erode gut barrier integrity in non-alcoholic steatohepatitis

Li, D. K.; Chaudhari, S. N.; Sojoodi, M.; Li, Y.; Adhikari, A. A.; Zhou, Z.; Zukerberg, L.; Shroff, S.; Barrett, S. C.; Boursier, J.; Diehl, A. M.; Sui, S. H.; Tanabe, K.; Chung, R. T.; Devlin, A. S.

10.1101/2021.03.24.436896 — physiology — Posted on 2021-03-25

1040 Weak effect of Gypsy retrotransposon bursts on Sonneratia alba salt stress gene expression

Wang, Y.; Dai, A.; Tang, T.

10.1101/2021.03.24.436880 — evolutionary biology — Posted on 2021-03-25

1041 Loss of STAT5 in adipocytes increases subcutaneous fat mass via sex-dependent and depot-specific pathways

Richard, A. J.; Hang, H.; Allerton, T. D.; Zhao, P.; Ghosh, S.; Elks, C. M.; Stephens, J. M.

10.1101/2021.03.24.436884 — cell biology — Posted on 2021-03-25

1042 Analysing and simulating energy-based models in biology using BondGraphTools

Cudmore, P.; Pan, M.; Gawthrop, P. J.; Crampin, E. J.

10.1101/2021.03.24.436763 — systems biology — Posted on 2021-03-25

1043 2,3,7,8-Tetrachlorodibenzo-p-dioxin elicited decreases in cobalamin inhibits methylmalonyl-CoA mutase activity redirecting propionyl-CoA metabolism to the β-oxidation-like pathway resulting in hepatic accumulation of the toxic intermediate acrylyl-CoA

Orlowska, K.; Fling, R. R.; Nault, R.; Zacharewski, T.

10.1101/2021.03.24.436837 — pharmacology and toxicology — Posted on 2021-03-25

1044 A cationic lipid site at the outward transmembrane face of a pentameric ligand-gated ion channel

Sridhar, A.; Lummis, S. C. R.; Pasini, D.; Mehregan, A.; Brams, M.; Kambara, K.; Bertrand, D.; Lindahl, E.; Howard, R. J.; Ulens, C.

10.1101/2021.03.24.436810 — biophysics — Posted on 2021-03-25

1045 High-throughput screen using fluorescence lifetime detects compounds that modulate myosin-binding protein C interactions with actin

Bunch, T. A.; Guhathakurta, P.; Lepak, V. C.; Thompson, A. R.; Kannassatega, R.-S.; Wilson, A.; Thomas, D. D.; Colson, B. A.

10.1101/2021.03.24.436879 — biophysics — Posted on 2021-03-25

1046 Novel cancer subtyping method based on patient-specific gene regulatory network

Nakazawa, M. A.; Tamada, Y.; Tanaka, Y.; Ikeguchi, M.; Higashihara, K.; Okuno, Y.

10.1101/2021.03.24.436731 — bioinformatics — Posted on 2021-03-25

1047 Effect of Inoculum Pretreatment on Alcohol Production from Volatile Fatty Acids through an Anaerobic Solventogenic Process

Mockaitis, G.; Bruant, G.; Foresti, E.; Zaiat, M.; Guiot, S. R.

10.1101/2021.03.23.436570 — bioengineering — Posted on 2021-03-25

1048 Single-cell analyses reveal a continuum of cell state and composition changes in the malignant transformation of polyps to colorectal cancer

Becker, W. R.; Nevins, S. A.; Chen, D. C.; Chiu, R.; Horning, A.; Laquindanum, R.; Mills, M.; Chaib, H.; Ladabaum, U.; Longacre, T.; Shen, J.; Esplin, E. D.; Kundaje, A.; Ford, J. M.; Curtis, C.; Snyder, M. P.; Greenleaf, W. J.

10.1101/2021.03.24.436532 — genomics — Posted on 2021-03-25

1049 Base editing using CRISPR/Cas9 in Drosophila

Marr, E.; Potter, C. J.

10.1101/2021.03.24.436868 — genetics — Posted on 2021-03-25

1050 The role of the Andean uplift as an asymmetrical barrier to gene flow in the Neotropical leaf-cutting ant Atta cephalotes

Munoz-Valencia, V.; Velez-Matinez, G. A.; Montoya-Lerma, J.; Diaz, F.

10.1101/2021.03.24.436865 — genetics — Posted on 2021-03-25

1051 Mitogenomic analyses provide further evidence for multiple miniaturization events during the evolution of Seychelles caecilian amphibians

Gwilt, A. J.; Streicher, J. W.; Maddock, S. T.

10.1101/2021.03.24.436854 — evolutionary biology — Posted on 2021-03-25

1052 Building alternative consensus trees and supertrees using k-means and Robinson and Foulds distance

Tahiri, N.; Fichet, B.; Makarenkov, V.

10.1101/2021.03.24.436812 — evolutionary biology — Posted on 2021-03-25

1053 Metacommunities from bacteria to birds: stronger environmental effects in Mediterranean than in tropical ponds.

Galvez, A.; Peres-Neto, P. R.; Castillo-Escriva, A.; Bonilla, F.; Camacho, A.; Garcia-Roger, E. M.; Iepure, S.; Miralles-Lorenzo, J.; Monros, J. S.; Olmo, C.; Picazo, A.; Rojo, C.; Rueda, J.; Sahuquillo, M.; Sasa, M.; Segura, M.; Armengol, X.; Mesquita-Joanes, F.

10.1101/2021.03.24.436596 — ecology — Posted on 2021-03-25

1054 Duox generated reactive oxygen species activate ATR/Chk1 to induce G2 arrest in Drosophila tracheoblasts

Kizhedathu, A.; Chhajed, P.; Yeramala, L.; Sain Basu, D.; Mukherjee, T.; Kutti, V. R.; Guha, A.

10.1101/2021.03.24.436759 — developmental biology — Posted on 2021-03-25

1055 Germ plasm anchors at tight junctions in the early zebrafish embryo

Rostam, N.; Goloborodko, A.; Riemer, S.; Hertel, A.; Klein, S.; Riedel, D.; Vorbrüggen, G.; Dosch, R.

10.1101/2021.03.24.436784 — developmental biology — Posted on 2021-03-25

1056 Identification of enzymes that are required for Rhodoquinone-dependent metabolism as targets for new species-specific inhibitors

Lautens, M. J.; Tan, J. H.; Serrat, X.; Del Borrello, S.; Schertzberg, M. R.; Fraser, A. G.

10.1101/2021.03.24.436840 — molecular biology — Posted on 2021-03-25

1057 Whole genome sequencing evidences higher rates of relapse in Clostridioides difficile infection caused by PCR ribotype 106

Suarez, L.; Lopez-Causape, C.; Oliver, A.; Mena, A.

10.1101/2021.03.23.436720 — microbiology — Posted on 2021-03-25

1058 A public vaccine-induced human antibody protects against SARS-CoV-2 and emerging variants

Schmitz, A. J.; Turner, J. S.; Liu, Z.; Aziati, I. D.; Chen, R. E.; Joshi, A.; Bricker, T. L.; Darling, T. L.; Adelsberg, D. C.; Al Soussi, W. B.; Case, J. B.; Lei, T.; Thapa, M.; Amanat, F.; O'Halloran, J. A.; Shi, P.-Y.; Presti, R. M.; Krammer, F.; Bajic, G.; Whelan, S. P. J.; Diamond, M. S.; Boon, A. C. M.; Ellebedy, A. H.

10.1101/2021.03.24.436864 — immunology — Posted on 2021-03-25

1059 Neural Activity Classification with Machine Learning Models Trained on Interspike Interval Time-Series Data

Lazarevich, I.; Prokin, I.; Gutkin, B.; Kazantsev, V.

10.1101/2021.03.24.436765 — neuroscience — Posted on 2021-03-25

1060 Lack of sex differences in gonadotropin-releasing hormone (GnRH) neuron potassium currents and excitability

DeFazio, R. A.; Moenter, S. M.

10.1101/2021.03.24.436851 — neuroscience — Posted on 2021-03-25

1061 Fast and statistically robust cell extraction from large-scale neural calcium imaging datasets

Inan, H.; Schmuckermair, C.; Tasci, T.; Ahanonu, B.; Hernandez, O.; Lecoq, J.; Dinc, F.; Wagner, M. J.; Erdogdu, M.; Schnitzer, M. J.

10.1101/2021.03.24.436279 — neuroscience — Posted on 2021-03-25

1062 Mugs and Plants: Object Semantic Knowledge Alters Perceptual Processing with Behavioral Ramifications

Dubbelde, D.; Shomstein, S. S.

10.1101/2021.03.24.436853 — neuroscience — Posted on 2021-03-25

1063 Hunger improves reinforcement-driven but not planned action

van Swieten, M. M. H.; Bogacz, R.; Manohar, S. G.

10.1101/2021.03.24.436435 — neuroscience — Posted on 2021-03-25

1064 Electrophysiological and Transcriptomic Features Reveal a Circular Taxonomy of Cortical Neurons

Rodriguez-Collado, A.; Rueda, C.

10.1101/2021.03.24.436849 — neuroscience — Posted on 2021-03-25

1065 Neural circuitry for maternal oxytocin release induced by infant cries

Valtcheva, S.; Issa, H. A.; Martin, K. A.; Jung, K.; Kwon, H.-B.; Froemke, R. C.

10.1101/2021.03.25.436883 — neuroscience — Posted on 2021-03-25

1066 A viral toolbox for conditional and transneuronal gene expression in zebrafish

Satou, C.; Neve, R. L.; Oyibo, H. K.; Arn Bouldoires, E.; Mori, T.; Higashijima, S.-i.; Keller, G. B.; Friedrich, R. W.

10.1101/2021.03.25.436574 — neuroscience — Posted on 2021-03-25

1067 Interhemispheric Connectivity Supports Load-Dependent Working Memory Maintenance for Complex Visual Stimuli

Reichert Plaska, C.; Ortega, J.; Gomes, B. A.; Ellmore, T. M.

10.1101/2021.03.24.436845 — neuroscience — Posted on 2021-03-25

1068 A computational probe into the behavioral and neural markers of atypical facial emotion processing in autism.

Kar, K.

10.1101/2021.03.24.436640 — neuroscience — Posted on 2021-03-25

1069 Brain virtual histology with X-ray phase-contrast tomography Part I: whole-brain myelin mapping in white-matter injury models

Chourrout, M.; Rositi, H.; Ong, E.; Hubert, V.; Paccalet, A.; Foucault, L.; Autret, A.; Fayard, B.; Olivier, C.; Bolbos, R.; Peyrin, F.; Crola Da Silva, C.; Meyronet, D.; Raineteau, O.; Elleaume, H.; Brun, E.; Chauveau, F.; Wiart, M.

10.1101/2021.03.24.436852 — neuroscience — Posted on 2021-03-25

1070 Stress is basic: ABA alkalinizes both the xylem sap and the cytosol of Arabidopsis vascular bundle sheath cellsby inhibiting their P-type H+-ATPaseand stimulating their V-type H+-ATPase

Torne, T.; Grunwald, Y.; Dalal, A.; Yaaran, A.; Moshelion, M.; Moran, N.

10.1101/2021.03.24.436813 — plant biology — Posted on 2021-03-25

1071 Mesenchymal-like glioma cells are enriched in the gelatin methacrylate hydrogels

Shah, N.; Hallur, P. M.; Ganesh, R. A.; Sonpatki, P.; Naik, D.; Chandrachari, K. P.; Puchalski, R. B.; Chaubey, A.

10.1101/2021.03.24.436751 — cancer biology — Posted on 2021-03-25

1072 Microsecond resolved infrared spectroscopy on non-repetitive protein reactions by applying caged-compounds and quantum cascade laser frequency combs

Norahan, M. J.; Horvath, R.; Woitzik, N.; Jouy, P.; Eigenmann, F.; Gerwert, K.; Koetting, C.

10.1101/2021.01.04.425172 — biophysics — Posted on 2021-03-25

1073 minicore: Fast scRNA-seq clustering with various distance measures

Baker, D. N.; Dyjack, N.; Braverman, V.; Hicks, S. C.; Langmead, B.

10.1101/2021.03.24.436859 — bioinformatics — Posted on 2021-03-25

1074 AutoCoEv: a high-throughput in silico pipeline for predicting novel protein-protein interactions

Petrov, P. B.; Awoniyi, L. O.; Sustar, V.; Mattila, P.

10.1101/2020.09.29.315374 — bioinformatics — Posted on 2021-03-25

1075 Autism_genepheno: Text mining of gene-phenotypeassociations reveals new phenotypic profiles ofautism-associated genes

Li, S.; Guo, Z.; Ioffe, J. B.; Hu, Y.; Zhen, Y.; Zhou, X.

10.1101/2021.03.24.436848 — bioinformatics — Posted on 2021-03-25

1076 Characterization of transcript enrichment and detection bias in single-nuclei RNA-seq for mapping of distinct human adipocyte lineages

Gupta, A.; Shamsi, F.; Altemose, N.; Dorlhiac, G. F.; Cypess, A. M.; White, A. P.; Patti, M. E.; Tseng, Y.-H.; Streets, A. M.

10.1101/2021.03.24.435852 — bioengineering — Posted on 2021-03-25

1077 Evaluation of solvents used for fabrication of microphysiological systems

Wen, X.; Takahashi, S.; Hatakeyama, K.; Kamei, K.-i.

10.1101/2021.03.24.436761 — bioengineering — Posted on 2021-03-25

1078 Degradable endovascular neural interface for minimally invasive neural recording and stimulation

Fanelli, A.; Ferlauto, L.; Zollinger, E. G.; Brina, O.; Reymond, P.; Machi, P.; Ghezzi, D.

10.1101/2021.03.24.436737 — bioengineering — Posted on 2021-03-25

1079 Extracellular Matrix Hydrogels Promote Expression of Paxillin, a Muscle-Tendon Junction Marker

Gaffney, L. S.; Fisher, M. B.; Freytes, D. O.

10.1101/2021.03.24.436805 — bioengineering — Posted on 2021-03-25

1080 Taking full advantage of modelling to better assess environmental risk due to xenobiotics

Charles, S.; Ratier, A.; Baudrot, V.; Multari, G.; Wu, D.; Siberchicot, A.; Lopes, C.

10.1101/2021.03.24.436474 — ecology — Posted on 2021-03-25

1081 Survey data on European organic multi-species livestock farms

Ulukan, D.; Steinmetz, L.; Moerman, M.; Bernes, G.; Blanc, M.; Brock, C.; Destruel, M.; Dumont, B.; Lang, E.; Meischner, T.; Moraine, M.; Oehen, B.; Parsons, D.; Primi, R.; Ronchi, B.; Schanz, L.; Vanwindekens, F.; Veysset, P.; Winckler, C.; Martin, G.; Benoit, M.

10.1101/2021.03.24.436791 — ecology — Posted on 2021-03-25

1082 Negative effects of agricultural intensification on energetic gain rates of a declining aerial insectivore

Garrett, D. R.; Paelletier, F.; Garant, D.; Belisle, M.

10.1101/2021.03.24.436831 — ecology — Posted on 2021-03-25

1083 Histological analysis of implantation embryos in large Japanese field mouse (Apodemus speciosus) and estimation of developmental stage.

Imai, H.; Kano, K.; Kusakabe, K. T.

10.1101/2021.03.24.436754 — developmental biology — Posted on 2021-03-25

1084 A folder mechanism ensures size uniformity among C. elegans individuals by coupling growth and development

Towbin, B. D.; Grosshans, H.

10.1101/2021.03.24.436858 — developmental biology — Posted on 2021-03-25

1085 The use of non-functional clonotypes as a natural spike-in for multiplex PCR bias correction in immune receptor repertoire profiling

Komkov, A. Y.; Smirnova, A. O.; Miroshnichenkova, A. M.; Volchkov, E. V.; Olshanskaya, Y. V.; Maschan, M. A.; Lebedev, Y. B.; Chudakov, D. M.; Mamedov, I.

10.1101/2021.03.24.436794 — immunology — Posted on 2021-03-25

1086 Transcriptional and cellular signatures of cortical morphometric similarity remodelling in chronic pain

Martins, D.; Dipasquale, O.; Veronese, M.; Turkheimer, F. E.; Loggia, M.; McMahon, S.; Williams, S. C.

10.1101/2021.03.24.436777 — neuroscience — Posted on 2021-03-25

1087 Modelling nonlinear dendritic processing of facilitation in a dragonfly target-tracking neuron

Bekkouche, B. M. B.; Shoemaker, P. A.; Fabian, J. M.; Rigosi, E.; Wiederman, S. D.; O'Carroll, D. C.

10.1101/2021.03.24.436732 — neuroscience — Posted on 2021-03-25

1088 A new chemoenzymatic semisynthetic approach provides novel insight into the role of phosphorylation beyond exon1 of Huntingtin and reveals N-terminal fragment length-dependent distinct mechanisms of aggregation

kolla, R.; Gopinath, P.; Ricci, J.; Reif, A.; Rostami, I.; Lashuel, H.

10.1101/2021.03.24.436743 — neuroscience — Posted on 2021-03-25

1089 Transthyretin promotes axon growth via regulation of microtubule dynamics and tubulin acetylation

Eira, J.; Magalhaes, J.; Macedo, N.; Pero, M. E.; Misgeld, T.; Sousa, M. M.; Bartolini, F.; Liz, M. A.

10.1101/2021.03.24.436762 — neuroscience — Posted on 2021-03-25

1090 Definition, modeling and detection of saccades in the face of post-saccadic oscillations

Schweitzer, R.; Rolfs, M.

10.1101/2021.03.24.436800 — neuroscience — Posted on 2021-03-25

1091 Extremely Fast pRF Mapping for Real-Time Applications

Bhat, S.; Lührs, M.; Goebel, R.; Senden, M.

10.1101/2021.03.24.436795 — neuroscience — Posted on 2021-03-25

1092 Anisotropy Measure from Three Diffusion-Encoding Gradient Directions

Aja-Fernandez, S.; Paris, G.; Tristan-Vega, A.

10.1101/2021.03.24.436786 — neuroscience — Posted on 2021-03-25

1093 Role of ventral subiculum neuronal ensembles in incubation of oxycodone craving after electric barrier-induced voluntary abstinence

Fredriksson, I.; Shekara, A.; Applebey, S. V.; Minier-Toribio, A.; Altidor, L.; Cifani, C.; Hope, B. T.; Bossert, J. M.; Shaham, Y.

10.1101/2021.03.24.436801 — neuroscience — Posted on 2021-03-25

1094 Modular Dynamic Biomolecular Modelling: The Unification of Stoichiometry, Thermodynamics, Kinetics and Data.

Gawthrop, P.; Pan, M.; Crampin, E.

10.1101/2021.03.24.436792 — systems biology — Posted on 2021-03-25

1095 A search-engine for single-cell epigenome profiles for multi-purpose applications

Mishra, S.; Chawla, S.; Pandey, N.; Sengupta, D.; KUMAR, V.

10.1101/2021.03.24.436738 — systems biology — Posted on 2021-03-25

1096 A stochastic oscillator model simulates the entrainment of vertebrate cellular clocks by light

Kumpost, V.; Vallone, D.; Gondi, S. B.; Foulkes, N. S.; Mikut, R.; Hilbert, L.

10.1101/2021.03.24.436598 — systems biology — Posted on 2021-03-25

1097 Investigations on regulation of miRNAs in rice reveal cyt signal transduction regulated miRNAs

Kansal, S.; Panwar, V.; Mutum, R. D.; Raghuvanshi, S.

10.1101/2021.03.24.436297 — plant biology — Posted on 2021-03-25

1098 Bacterial Rdl2 dsRNA increased the insecticidal activity of GABAR blockers and allosteric modulators against Plutella xylostella

Wang, K.; Li, B.; Yu, Y.; Wei, J.; Zhu, J.; Wang, J.; Lin, F.; Xu, H.

10.1101/2021.03.24.436736 — pharmacology and toxicology — Posted on 2021-03-25

1099 Correction of multiple-blinking artefacts in photoactivated localisation microscopy

Jensen, L. G.; Yee Hoh, T.; Williamson, D. J.; Griffie, J.; Sage, D.; Rubin-Delanchy, P.; Owen, D. M.

10.1101/2021.03.24.436128 — biophysics — Posted on 2021-03-25

1100 Independent Markov Decomposition: Towards modeling kinetics of biomolecular complexes

Hempel, T.; del Razo, M. J.; Lee, C. T.; Taylor, B. C.; Amaro, R. E.; Noe, F.

10.1101/2021.03.24.436806 — biophysics — Posted on 2021-03-25

1101 Deep learning-based chest X-ray age serves as a novel biomarker for cardiovascular aging

Ieki, H.; Ito, K.; Saji, M.; Kawakami, R.; Nagatomo, Y.; Koyama, S.; Matsunaga, H.; Miyazawa, K.; Ozaki, K.; Onouchi, Y.; Katsushika, S.; Matsuoka, R.; Shinohara, H.; Yamaguchi, T.; Kodera, S.; Higashikuni, Y.; Fujiu, K.; Akazawa, H.; Isobe, M.; Yoshikawa, T.; Komuro, I.

10.1101/2021.03.24.436773 — bioinformatics — Posted on 2021-03-25

1102 Honeybee dance-followers respond similarly to dances regardless of their spatial information content

Hasenjager, M. J.; Hoppitt, W.; Leadbeater, E.

10.1101/2021.03.24.436796 — animal behavior and cognition — Posted on 2021-03-25

1103 Independent somatic evolution underlies clustered neuroendocrine tumors in the human small intestine

Elias, E.; Ardalan, A.; Lindberg, M.; Reinsbach, S.; Muth, A.; Nilsson, O.; Arvidsson, Y.; Larsson, E.

10.1101/2020.05.06.080499 — genomics — Posted on 2021-03-25

1104 gen3sis: the general engine for eco-evolutionary simulations on the origins of biodiversity

Hagen, O.; Flueck, B.; Fopp, F.; Sarmento Cabral, J.; Hartig, F.; Pontarp, M.; Rangel, T. F.; Pellissier, L.

10.1101/2021.03.24.436109 — evolutionary biology — Posted on 2021-03-25

1105 The species-specificity of energy landscapes for soaring birds, and its consequences for transferring suitability models across species

Scacco, M.; Arrondo, E.; Donazar, J. A.; Flack, A.; Sanchez-Zapata, J. A.; Duriez, O.; Wikelski, M.; Safi, K.

10.1101/2021.03.24.436775 — ecology — Posted on 2021-03-25

1106 Umibato: estimation of time-varying microbial interaction using continuous-time regression hidden Markov model

Hosoda, S.; Fukunaga, T.; Hamada, M.

10.1101/2021.01.28.428580 — microbiology — Posted on 2021-03-25

1107 Molecular and cellular insight into Escherichia coli SslE and its role during biofilm maturation

Corsini, P.; Wang, S.; Rehman, S.; Fenn, K.; Sagar, A.; Sirovica, S.; Cleaver, L.; Edwards-Gayle, C. J. C.; Mastroianni, G.; Dorgan, B.; Sewell, L. M.; Lynham, S.; Iuga, D.; Franks, W. T.; Jarvis, J.; Carpenter, G. H.; Curtis, M. A.; Bernado, P.; Darbari, V. C.; Garnett, J. A.

10.1101/2021.02.07.430137 — microbiology — Posted on 2021-03-25

1108 Homeostatic cerebellar compensation of age-related changes of vestibulo-ocular reflex adaptation: a computational epidemiology study

Luque, N. R.; Naveros, F.; Ros, E.; Arleo, A.

10.1101/2020.08.03.233833 — neuroscience — Posted on 2021-03-25

1109 Rescue of two trafficking-defective variants of the neuronal glycine transporter GlyT2 associated to hyperekplexia

de la Rocha-Munoz, A.; Melgarejo, E.; Aragon, C.; López-Corcuera, B.

10.1101/2021.03.24.436638 — neuroscience — Posted on 2021-03-25

1110 Apoptosis is not conserved in plants as revealed by critical examination of a model for plant apoptosis-like cell death

Minina, E. A.; Dauphinee, A. N.; Ballhaus, F.; Gogvadze, V.; Smertenko, A. P.; Bozhkov, P. V.

10.1101/2020.09.26.314583 — plant biology — Posted on 2021-03-25

1111 Sequential 3D OrbiSIMS and LESA-MS/MS-based metabolomics for prediction of brain tumor relapse from sample-limited primary tissue archives

Meurs, J.; Scurr, D. J.; Lourdusamy, A.; Storer, L. C. D.; Grundy, R. G.; Alexander, M. R.; Rahman, R.; Kim, D.-H.

10.1101/2020.07.15.182071 — cancer biology — Posted on 2021-03-25

1112 partR2: Partitioning R2 in generalized linear mixed models

Stoffel, M. A.; Nakagawa, S.; Schielzeth, H.

10.1101/2020.07.26.221168 — bioinformatics — Posted on 2021-03-25

1113 Tracing the evolution of aneuploid cancers from multiregional sequencing

Chattopadhyay, S.; Karlsson, J.; Valind, A.; Andersson, N.; Gisselsson, D.

10.1101/2020.11.11.376467 — bioinformatics — Posted on 2021-03-25

1114 AA_stat: intelligent profiling of in vivo and in vitro modifications from open search results

Levitsky, L. I.; Bubis, J. A.; Gorshkov, M. V.; Tarasova, I. A.

10.1101/2020.09.07.286161 — bioinformatics — Posted on 2021-03-25

1115 Consensus clustering applied to multi-omic disease subtyping

BRIERE, G.; Darbo, E.; Thebault, P.; Uricaru, R.

10.1101/2020.10.19.345389 — bioinformatics — Posted on 2021-03-25

1116 Genetic drift from the out-of-Africa bottleneck leads to biased estimation of genetic architecture and selection

Ashraf, B.; Lawson, D. J.

10.1101/2020.08.17.254110 — genetics — Posted on 2021-03-25

1117 Avoiding tensional equilibrium in cells migrating on a matrix with cell-scale stiffness-heterogeneity

Ebata, H.; Kidoaki, S.

10.1101/2020.10.15.342006 — biophysics — Posted on 2021-03-24

1118 Ecology of active viruses and their bacterial hosts in frozen Arctic peat soil revealed with H218O stable isotope probing metagenomics

Trubl, G.; Kimbrel, J.; Liquet-Gonzalez, J.; Nuccio, E. E.; Weber, P. K.; Pett-Ridge, J.; Jansson, J. K.; Waldrop, M.; Blazewicz, S. J.

10.1101/2021.01.25.428156 — microbiology — Posted on 2021-03-25

1119 Neurogenesis-induced forgetting is associated with reduced neuronal activity in CA1 during context fear memory retrieval

Evans, A.; Scott, G. A.; Epp, J. R.

10.1101/2021.03.24.436893 — neuroscience — Posted on 2021-03-24

1120 A Pilot Study Using Two Novel fMRI Tasks: Understanding Theory of Mind and Emotion Recognition Among Children With ASD

Han, Y.; Prelock, P. A.; Coderre, E. L.; Orr, J. M.

10.1101/2021.03.24.436877 — neuroscience — Posted on 2021-03-24

1121 Fibrinogen and Complement Factor H are promising CSF protein biomarker(s) for Parkinson's disease with cognitive impairment- A Proteomics and ELISA based study

Naskar, A.; Stezin, A.; Arpitha, D. S.; Hegde, S.; Philip, M.; Kamble, N.; Saini, J.; Yadav, Y.; Sandhya, K.; Tatu, U.; Pal, P. K.; Alladi, P. A.

10.1101/2021.03.19.436097 — neuroscience — Posted on 2021-03-24

1122 Innate Organization of the Human Brain

Molloy, M. F.; Saygin, Z. M.

10.1101/2021.03.24.436788 — neuroscience — Posted on 2021-03-24

1123 PyDamage: automated ancient damage identification and estimation for contigs in ancient DNA de novo assembly

Borry, M.; Huebner, A.; Rohrlach, A. B.; Warinner, C. G.

10.1101/2021.03.24.436838 — bioinformatics — Posted on 2021-03-24

1124 Fine scale prediction of ecological community composition using a two-step sequential machine learning ensemble

Civantos, I.; Garcia-Algarra, J.; Garcia-Callejas, D.; Galeano, J.; Godoy, O.; Bartomeus, I.

10.1101/2021.03.24.436771 — ecology — Posted on 2021-03-24

1125 The natural sequence of events in larval settlement and metamorphosis of Hydroides elegans (Polychaeta; Serpulidae)

Hadfield, M. G.; Freckelton, M. L.; Nedved, B. T.

10.1101/2021.03.24.436767 — developmental biology — Posted on 2021-03-24

1126 A new hypothesis for type 1 diabetes risk: The at-risk allele at rs3842753 associates with increased beta cell INS mRNA in a meta-analysis of single cell RNA sequencing data

Wang, S.; Flibotte, S.; Camunas-Soler, J.; MacDonald, P. E.; Johnson, J. D.

10.1101/2020.12.06.413971 — cell biology — Posted on 2021-03-24

1127 High-throughput Interpretation of Killer-cell Immunoglobulin-like Receptor Short-read Sequencing Data with PING

Marin, W.; Dandekar, R.; Augusto, D. G.; Yusufali, T.; Heyn, B.; Hofmann, J.; Lange, V.; Sauter, J.; Norman, P. J.; Hollenbach, J. A.

10.1101/2021.03.24.436770 — immunology — Posted on 2021-03-24

1128 Profiling DNA break sites and transcriptional changes in response to contextual fear learning

Stott, R.; Kritsky, O.; Tsai, L.-H.

10.1101/2021.03.24.436768 — neuroscience — Posted on 2021-03-24

1129 Sequence and phylogenetic analysis revealed structurally conserved domains and motifs in lincRNA-p21

Maulik, A.; Bandopadhyay, D.; Singh, M.

10.1101/2021.03.24.436769 — bioinformatics — Posted on 2021-03-24

1130 Long-Term Metabolomics Reference Material

Gouveia, G. J.; Shaver, A. O.; Garcia, B. M.; Morse, A. M.; Andersen, E. C.; Edison, A. S.; McIntyre, L. M.

10.1101/2021.03.24.436834 — biochemistry — Posted on 2021-03-24

1131 Cell group analysis reveals changes in upper-layer neurons associated with schizophrenia

Dai, R.; Chen, L.; Liu, S.; Wu, C.-T.; Chen, Y.; Jiang, Y.; Dai, J.; Wang, Q.; Kopp, R.; Yu, G.; Wang, Y.; Chen, C.; Liu, C.

10.1101/2020.10.22.351213 — genomics — Posted on 2021-03-24

1132 Non-additive biotic interactions improve predictions of tropical tree growth and impact community size structure

Lai, H. R.; Chong, K. Y.; Yee, A. T. K.; Mayfield, M. M.; Stouffer, D. B.

10.1101/2020.09.16.300616 — ecology — Posted on 2021-03-24

1133 Nasonia segmentation is regulated by an ancestral insect segmentation regulatory network also present in flies

Taylor, S.; Dearden, P.

10.1101/2021.03.23.436706 — developmental biology — Posted on 2021-03-24

1134 Long-Term Imaging of Living Adult Zebrafish

Castranova, D.; Samasa, B.; Venero Galanternik, M.; Gore, A.; Weinstein, B. M.

10.1101/2021.03.19.436170 — developmental biology — Posted on 2021-03-24

1135 Quantitative single cell 5hmC sequencing reveals non-canonical gene regulation by non-CG hydroxymethylation

Fabyanic, E. B.; Hu, P.; Qiu, Q.; Wang, T.; Berrios, K. N.; Flournoy, J.; Connolly, D. R.; Zhou, Z.; Kohli, R. M.; Wu, H.

10.1101/2021.03.23.434325 — genomics — Posted on 2021-03-24

1136 Dynamic sampling bias and overdispersion induced by skewed offspring distributions

Okada, T.; Hallatschek, O.

10.1101/2021.03.09.434663 — evolutionary biology — Posted on 2021-03-24

1137 The Hippo pathway transcriptional co-activator YAP is involved in head regeneration and bud development in Hydra

Unni, M. K.; Reddy, P. C.; Galande, S.

10.1101/2021.03.24.436861 — developmental biology — Posted on 2021-03-24

1138 TRIM28-dependent SUMOylation protects the adult ovary from the male pathway

Rossitto, M.; Dejardin, S.; Rands, C. M.; Legras, S.; Migale, R.; Rafiee, M.-R.; Neirijnck, Y.; Pruvost, A.; Nguyen, A. L.; Bossis, G.; Cammas, F. M.; Le Gallic, L.; Wilhelm, D.; Boizet-Bonhoure, B.; Lovell-Badge, R.; Nef, S.; Poulat, F.

10.1101/2021.03.24.436749 — developmental biology — Posted on 2021-03-24

1139 Human eosinophil cationic protein manifests alarmin activity through its basicity and ribonuclease activity

Attery, A.; Saha, I.; Tailor, P.; Batra, J. K.

10.1101/2021.03.24.436724 — molecular biology — Posted on 2021-03-24

1140 Herpesviral induction of germline transcription factor DUX4 is critical for viral gene expression

Walter, S.; Franke, V.; Drayman, N.; Wyler, E.; Tay, S.; Landthaler, M.; Akalin, A.; Ensser, A.; Full, F.

10.1101/2021.03.24.436599 — microbiology — Posted on 2021-03-24

1141 Environmental genomics points to non-diazotrophic Trichodesmium species abundant and widespread in the open ocean

Delmont, T. O.

10.1101/2021.03.24.436785 — microbiology — Posted on 2021-03-24

1142 Eukaryotic rather than prokaryotic microbiomes change over seasons in rewetted fen peatlands

Wang, H.; Weil, M.; Dumack, K.; Zak, D.; Muench, D.; Guenther, A.; Jurasinski, G.; Blume-Werry, G.; Kreyling, J.; Urich, T.

10.1101/2020.02.16.951285 — microbiology — Posted on 2021-03-24

1143 A candidate neuroimaging biomarker for detection of neurotransmission-related functional alterations and prediction of pharmacological analgesic response in chronic pain

Martins, D.; Veronese, M.; Turkheimer, F. E.; Howard, M. A.; Williams, S. C.; Dipasquale, O.

10.1101/2021.02.17.431572 — neuroscience — Posted on 2021-03-24

1144 Loss of Nuclear DNA ligase III Can Revert PARP Inhibitor Resistance in BRCA1-deficient Cells by Increasing DNA Replication Stress

Paes Dias, M.; Tripathi, V.; Heijden, I. v. d.; Cong, K.; Manolika, E.-M.; Galanos, P.; Bhin, J.; Gogola, E.; Annunziato, S.; Lieftink, C.; Andujar-Sanchez, M.; Ven, M. v. d.; Chakrabarty, S.; Beijersbergen, R. L.; Bartkova, J.; Rottenberg, S.; Cantor, S.; Bartek, J.; Chaudhuri, A. R.; Jonkers, J.

10.1101/2021.03.24.436323 — cancer biology — Posted on 2021-03-24

1145 The ratio of cytotoxic lymphocytes to M2-like macrophages is prognostic in immunogenic tumors

Mezheyeuski, A.; Backman, M.; Mattsson, J.; Martin-Bernabe, A.; Larsson, C.; Hrynchyk, I.; Hammarström, K.; Ström, S.; Ekström, J.; Mauchanski, S.; Khelashvili, S.; Agnarsdottir, M.; Edqvist, P.-H.; Huvila, J.; Segersten, U.; Malmström, P.-U.; Botling, J.; Nodin, B.; Hedner, C.; Borg, D.; Bärndstedt, J.; Sartor, H.; Leandersson, K.; Glimelius, B.; Portyanko, A.; Ponten, F.; Jirström, K.; Micke, P.; Sjöblom, T.

10.1101/2021.03.24.436814 — cancer biology — Posted on 2021-03-24

1146 Full scale structural, mechanical and dynamical properties of HIV-1 liposomes.

Bryer, A.; Lyman, E.; Reddy, T.; Perilla, J. R.

10.1101/2021.03.24.436841 — biophysics — Posted on 2021-03-24

1147 Class I Histone Deacetylases (HDAC1-3) are Histone Lysine Delactylases

Moreno-Yruela, C.; Zhang, D.; Wei, W.; Baek, M.; Gao, J.; Nielsen, A. L.; Bolding, J. E.; Yang, L.; Jameson, S. T.; Wong, J.; Olsen, C. A.; Zhao, Y.

10.1101/2021.03.24.436780 — biochemistry — Posted on 2021-03-24

1148 ADAR2-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair

Jimeno, S.; Prados-Carvajal, R.; Fernandez-Avila, M. J.; Silva, S.; Silvestris, D. A.; Endara-Coll, M.; Domingo-Prim, J.; Mejias-Navarro, F.; Rodriguez-Real, G.; Romero-Franco, A.; Jimeno-Gonzalez, S.; Barroso, S.; Cesarini, V.; Aguilera, A.; Gallo, A.; Visa, N.; Huertas, P.

10.1101/2021.03.24.436729 — genetics — Posted on 2021-03-24

1149 Patterns of recent natural selection on genetic loci associated with sexually differentiated human body size and shape phenotypes

Arner, A. M.; Grogan, K. E.; Grabowski, M.; Reyes-Centeno, H.; Perry, G. H.

10.1101/2020.06.17.155549 — evolutionary biology — Posted on 2021-03-24

1150 Whole genome resequencing data enables a targeted SNP panel for conservation and aquaculture of Oreochromis cichlid fishes

Ciezarek, A.; Ford, A.; Etherington, G.; Nasser, K.; Malinsky, M.; Mehta, T.; Penso-Dolfin, L.; Ngatunga, B.; Shechonge, A.; Tamatamah, R.; Haerty, W.; di Palma, F.; Genner, M.; Turner, G. F.

10.1101/2021.03.24.436760 — evolutionary biology — Posted on 2021-03-24

1151 Directed differentiation of hPSCs through lateral plate mesoderm for generation of articular cartilage progenitors

Smith, C. A.; Humphreys, P. A.; Naven, M. A.; Mancini, F.; Kimber, S. J.

10.1101/2021.03.24.436807 — developmental biology — Posted on 2021-03-24

1152 circMRPS35 promotes malignant progression and cisplatin resistance in hepatocellular cancer

Li, P.; Song, R.; Liu, H.; Liu, M.; Yin, F.; Ma, S.; Jia, X.; Lu, X.; Zhong, Y.; Li, X.; Li, X.

10.1101/2021.03.24.436699 — cell biology — Posted on 2021-03-24

1153 Fine-tuned repression of Drp1 driven mitochondrial fission primes a slow cycling stem/progenitor-like state towards accelerating neoplastic transformation of keratinocytes

Mitra, K.; Spurlock, B. M.; Parker, D.; Basu, M.; Hjelmeland, A.; Gc, S.; Liu, S.; Siegal, G. P.; Gunter, A.; Moran, A.

10.1101/2021.03.05.434102 — cell biology — Posted on 2021-03-24

1154 High Mobility Group Box 1 enhances ADP-mediated platelet activation by increasing platelet surface P2Y12 localization

Nolfi-Donegan, D.; Annarapu, G.; Maurer, L.; Hillery, C.; Shiva, S.

10.1101/2021.03.24.436776 — cell biology — Posted on 2021-03-24

1155 The Arabidopsis F-box protein FBW2 degrades AGO1 to avoid spurious loading of illegitimate small RNA

Hacquard, T.; Clavel, M.; Baldrich, P.; Lechner, E.; Perez-Salamo, I.; Schepetilnikov, M.; Derrien, B.; Dubois, M.; Hammann, P.; Kuhn, L.; Brun, D.; Bouteiller, N.; Vaucheret, H.; Meyers, B.; Genschik, P.

10.1101/2021.03.24.436811 — cell biology — Posted on 2021-03-24

1156 Phosphorylation-dependent mitotic SUMOylation drives nuclear envelope-chromatin interactions

Ptak, C.; Saik, N. O.; Premashankar, A.; Lapetina, D. L.; Aitchison, J.; Montpetit, B.; Wozniak, R. W.

10.1101/2021.03.24.436817 — cell biology — Posted on 2021-03-24

1157 Genome-wide molecular recording using Live-seq

Chen, W.; Guillaume-Gentil, O.; Dainese, R.; Rainer, P. Y.; Zachara, M.; Gabelein, C. G.; Vorholt, J. A.; Deplancke, B.

10.1101/2021.03.24.436752 — molecular biology — Posted on 2021-03-24

1158 Development of an integrated structural biology platform specialized for sub-100 kDa protein complexes to support biologics discovery and rational engineering

Iozzo, Y.; Qiu, Y.; Xu, A.; Park, A.; Wendt, M.; Zhou, Y.

10.1101/2021.03.24.436836 — molecular biology — Posted on 2021-03-24

1159 Discovery of lipotoxicity-sensitive transcription factors in non-alcoholic steatohepatitis

Perez-Schindler, J.; Vargas-Fernandez, E.; Karrer-Cardel, B.; Ritz, D.; Schmidt, A.; Handschin, C.

10.1101/2021.03.24.436772 — molecular biology — Posted on 2021-03-24

1160 Uncharted biosynthetic potential of the ocean microbiome

Paoli, L.; Ruscheweyh, H.-J.; Forneris, C. C.; Kautsar, S.; Clayssen, Q.; Salazar, G.; Milanese, A.; Gehrig, D.; Larralde, M.; Carroll, L.; Sanchez, P.; Zayed, A. A.; Cronin, D. R.; Acinas, S. G.; Bork, P.; Bowler, C.; Delmont, T. O.; Sullivan, M. B.; Wincker, P.; Zeller, G.; Robinson, S. L.; Piel, J.; Sunagawa, S.

10.1101/2021.03.24.436479 — microbiology — Posted on 2021-03-24

1161 On-person adaptive evolution of Staphylococcus aureus during atopic dermatitis increases disease severity

Key, F. M.; Khadka, V. D.; Romo-Gonzalez, C.; Blake, K. J.; Deng, L.; Lynn, T. C.; Lee, J. C. M.; Chiu, I.; Garcia, M. T.; Lieberman, T. D.

10.1101/2021.03.24.436824 — microbiology — Posted on 2021-03-24

1162 Tradeoffs for a viral mutant with enhanced replication speed

Lanahan, M. R.; Pfeiffer, J. K.

10.1101/2021.03.24.436823 — microbiology — Posted on 2021-03-24

1163 Seasonal dynamics of phytoplankton and bacterioplankton at the ultra-oligotrophic southeastern Mediterranean Sea

Reich, T.; Ben-Ezra, T.; Belkin, N.; Tsemel, A.; Aharonovich, D.; Roth-Rosenberg, D.; Givati, S.; Bialik, O.; Herut, B.; Berman-Frank, I.; Frada, M.; Krom, M. D.; Lahahn, Y.; Rahav, E.; Sher, D.

10.1101/2021.03.24.436734 — microbiology — Posted on 2021-03-24

1164 Heterotrophic bacterial diazotrophs are more abundant than their cyanobacterial counterparts in metagenomes covering most of the sunlit ocean

Delmont, T. O.; Pierella Karlusich, J. J.; Veseli, I.; Fuessel, J.; Eren, A. M.; Foster, R. A.; Bowler, C.; Wincker, P.; Pelletier, E.

10.1101/2021.03.24.436778 — microbiology — Posted on 2021-03-24

1165 Interchangeability of Periplasmic Adaptor Proteins AcrA and AcrE in forming functional efflux pumps with AcrD in Salmonella Typhimurium

Alav, I.; Bavro, V. N.; Blair, J. M. A.

10.1101/2021.03.24.436855 — microbiology — Posted on 2021-03-24

1166 MafF is an antiviral host factor that suppresses transcription from Hepatitis B Virus core promoter

Ibrahim, M. K.; Abdelhafez, T. H.; Takeuchi, J. S.; Wakae, K.; Sugiyama, M.; Tsuge, M.; Ito, M.; Watashi, K.; El Kassas, M.; Kato, T.; Murayama, A.; Suzuki, T.; Chayama, K.; Shimotohno, K.; Muramatsu, M.; Aly, H. H.; Wakita, T.

10.1101/2020.07.29.227793 — microbiology — Posted on 2021-03-24

1167 The impact of COVID-19 vaccination campaigns accounting for antibody-dependent enhancement

Adil M. Y., N.; Tsoungui Obama, H. C. J.; Ngucho Yvan Mbeutchou, J.; Kwamou Ngaha, S. F.; Kayanula, L.; Kamanga, G.; Ibrahim, T. B.; Bwanu Iliya, P.; Iyanda, S. B.; Alawam Nemer, L. H. M.; Helle, K. B.; Teboh-Ewungkem, M. I.; Schneider, K. A.

10.1101/2021.01.04.425198 — immunology — Posted on 2021-03-24

1168 Sex differences and similarities in the neuroimmune response to central administration of poly I:C

Posillico, C. K.; Garcia-Hernandez, R. E.; Tronson, N. C.

10.1101/2020.11.23.394742 — neuroscience — Posted on 2021-03-24

1169 Transcriptional Diversity of Medium Spiny Neurons in the Primate Striatum

He, J.; Kleyman, M.; Chen, J.; Alikaya, A.; Rothenhoefer, K. M.; Ozturk, B. E.; Wirthlin, M.; Fish, K.; Byrne, L. C. T.; Pfenning, A. R.; Stauffer, W. R.

10.1101/2020.10.25.354159 — neuroscience — Posted on 2021-03-24

1170 Neural dynamics of semantic categorization in semantic variant of Primary Progressive Aphasia.

Borghesani, V.; Dale, C. L.; Lukic, S.; Hinkley, L. B. N.; Lauricella, M.; Shwe, W.; Miziuri, D.; Honma, S.; Miller, Z.; Miller, B. L.; Houde, J.; Gorno-Tempini, M. L.; Nagarajan, S.

10.1101/2020.10.07.329698 — neuroscience — Posted on 2021-03-24

1171 Tractography dissection variability: what happens when 42 groups dissect 14 white matter bundles on the same dataset?

Schilling, K. G.; Rheault, F.; Petit, L.; Hansen, C. B.; Nath, V.; Yeh, F.-C.; Girard, G.; Barakovic, M.; Rafael-Patino, J.; Yu, T.; Fischi-Gomez, E.; Pizzolato, M.; Ocampo-Pineda, M.; Schiavi, S.; Canales-Rodriguez, E. J.; Daducci, A.; Granziera, C.; Innocenti, G.; Thiran, J.-P.; Mancini, L.; Wastling, S.; Cocozza, S.; Petracca, M.; Pontillo, G.; Mancini, M.; Vos, S. B.; Vakharia, V. N.; Duncan, J. S.; Melero, H.; Manzanedo, L.; Sanz-Morales, E.; Pena-Melian, A.; Calamante, F.; Attye, A.; Cabeen, R. P.; Korobova, L.; Toga, A. W.; Ambili Vijayakumari, A.; Parker, D.; Verma, R.; Radwan, A.; Sun

10.1101/2020.10.07.321083 — neuroscience — Posted on 2021-03-24

1172 Plant immune system activation is necessary for efficient interaction with auxin secreting beneficial bacteria

Tzipilevich, E.; Benfey, P. N.

10.1101/2021.03.23.436641 — plant biology — Posted on 2021-03-24

1173 Synthetic Promoter Designs Enabled by a Comprehensive Analysis of Plant Core Promoters

Jores, T.; Tonnies, J.; Wrightsman, T.; Buckler, E. S.; Cuperus, J.; Fields, S.; Queitsch, C.

10.1101/2021.01.07.425784 — plant biology — Posted on 2021-03-24

1174 Macrophage-derived cholesterol contributes to therapeutic resistance in prostate cancer

El-Kenawi, A.; Dominguez-Viqueira, W.; Liu, M.; Awasthi, S.; Keske, A.; Steiner, K. K.; Noel, L.; Dhillon, J.; Gillies, R. J.; Yamoah, K.; Yu, X.; Koomen, J.; Gatenby, R. A.; Ruffell, B.

10.1101/2021.03.24.436480 — cancer biology — Posted on 2021-03-24

1175 Degradation of Alzheimers Amyloid-beta by a Catalytically Inactive Insulin Degrading Enzyme

Sahoo, B.; Panda, P. K.; Liang, W.; Tang, W.-J.; Ahuja, R.; Ramamoorthy, A.

10.1101/2020.04.23.057505 — biophysics — Posted on 2021-03-24

1176 Analytical solutions of the chemical master equation with bursty production and isomerization reactions

Gorin, G.; Pachter, L.

10.1101/2021.03.24.436847 — biophysics — Posted on 2021-03-24

1177 Navigating the amino acid sequence space between functional proteins using a deep learning framework

Bitard-Feildel, T.

10.1101/2020.11.09.375311 — bioinformatics — Posted on 2021-03-24

1178 Computational Model to Quantify the Growth of Antibiotic Resistant Bacteria in Wastewater

Sutradhar, I.; Ching, C.; Desai, D.; Suprenant, M.; Briars, E.; Heins, Z.; Khalil, A. S.; Zaman, M. H.

10.1101/2020.10.09.333575 — bioengineering — Posted on 2021-03-24

1179 The landscape of alternative polyadenylation in single cells of the developing mouse embryo

Agarwal, V.; Lopez-Darwin, S.; Kelley, D. R.; Shendure, J.

10.1101/2021.01.21.427498 — genomics — Posted on 2021-03-24

1180 Proteins with prion-like domains can form viscoelastic condensates that enable membrane remodeling and endocytosis

Bergeron-Sandoval, L.-P.; Kumar, S.; Heris, H. K.; Chang, C.; Cornell, C. E.; Keller, S. L.; Hendricks, A. G.; Ehrlicher, A. J.; Francois, P.; Pappu, R. V.; Michnick, S. W.

10.1101/145664 — cell biology — Posted on 2021-03-24

1181 Arginine Methylation Regulates SARS-CoV-2 Nucleocapsid Protein Function and Viral Replication

Cai, T.; Yu, Z.; Wang, Z.; Liang, C.; Richard, S.

10.1101/2021.03.24.436822 — molecular biology — Posted on 2021-03-24

1182 A Meta-analysis of the known Global Distribution and Host Range of the Ralstonia Species Complex

Lowe-Power, T.; Avalos, J.; Charco Munoz, M.; Chipman, K.

10.1101/2020.07.13.189936 — microbiology — Posted on 2021-03-24

1183 The capacity to produce hydrogen sulfide (H2S) via cysteine degradation is ubiquitous in the human gut microbiome

Braccia, D. J.; Jiang, X.; Pop, M.; Hall, B.

10.1101/2021.03.24.436781 — microbiology — Posted on 2021-03-24

1184 Factors Associated with Emerging and Re-emerging of SARS-CoV-2 Variants

Spratt, A. N.; Kannan, S. K.; Woods, L. T.; Weisman, G. A.; Quinn, T. D.; Lorson, C. L.; Sonnerborg, A.; Byrareddy, S. N.; Singh, K.

10.1101/2021.03.24.436850 — bioinformatics — Posted on 2021-03-24

1185 Mild CF Lung Disease is Associated with Bacterial Community Stability

Hampton, T. H.; Thomas, D.; van der Gast, C.; Stanton, B. A.; O'Toole, G.

10.1101/2021.03.23.436717 — microbiology — Posted on 2021-03-24

1186 New detection of SARS-CoV-2 in two cats height months after COVID-19 outbreak appearance in France

Fritz, M.; Nesi, N.; Denolly, S.; Boson, B.; Legros, V.; Rosolen, S. G.; Briend-Marchal, A.; Ar Gouil, M.; Leroy, E. M.

10.1101/2021.03.24.436830 — microbiology — Posted on 2021-03-24

1187 Exploring Leishmania-Host Interaction with Reactome, a Database of Biological Pathways and Processes

Murillo Silva, J. I.; Jassal, B.; Gomez, M. A.; Hermjakob, H.

10.1101/2021.03.23.436718 — systems biology — Posted on 2021-03-24

1188 An open-source and wearable system for measuring 3D human motion in real-time

Slade, P.; Habib, A.; Hicks, J. L.; Delp, S. L.

10.1101/2021.03.24.436725 — bioengineering — Posted on 2021-03-24

1189 Responses of Oil Palm Pollinator, Elaeidobius kamerunicus to Different Concentrations of Estragoles

Fahmi-Halil, M.; Haris-Hussain, M.; Mirad, R.; AB, I.; JALINAS, J.

10.1101/2021.03.24.436726 — animal behavior and cognition — Posted on 2021-03-24

1190 Genetic differentiation of Xylella fastidiosa following the introduction into Taiwan

Castillo, A. I.; Tsai, C.-W.; Su, C.-C.; Weng, L.-W.; Lin, Y.-C.; Cho, S.-T.; Almeida, R. P. P.; Kuo, C.-H.

10.1101/2021.03.24.436723 — genomics — Posted on 2021-03-24

1191 Euchromatin factors HULC and Set1C affect heterochromatin organization for mating-type switching in fission yeast Schizosaccharomyces pombe

Chavez, A. E.; Maki, T.; Tsubouchi, H.; Handa, T.; Kimura, H.; Haber, J. E.; Thon, G.; Iwasaki, H.

10.1101/2021.03.23.436714 — genetics — Posted on 2021-03-24

1192 Epidemiological dynamics of viral infection in a marine pico-eukaryote

Listmann, L.; Heath, S.; Vale, P. F.; Schaum, E.; Collins, S.

10.1101/2021.03.23.436719 — microbiology — Posted on 2021-03-24

1193 Aberrant modulation of brain activity underlies impaired working memory following traumatic brain injury

Taing, A. S.; Mundy, M. E.; Ponsford, J. L.; Spitz, G.

10.1101/2021.03.23.436708 — neuroscience — Posted on 2021-03-24

1194 Fuzzy-Discernibility Matrix-based an Efficient Feature Selection Technique for Improved Motor-Imagery EEG Signal Classification

Chatterjee, R.; Sanyal, D. K.; Chatterjee, A.

10.1101/2021.03.24.436722 — neuroscience — Posted on 2021-03-24

1195 Derivation of stationary distributions of biochemical reaction networks via structure transformation

Hong, H.; Kim, J.; Al-Radhawi, M. A.; Sontag, E. D.; Kim, J. K.

10.1101/2021.03.23.436681 — systems biology — Posted on 2021-03-24

1196 Miniaturizing wet scrubbers for aerosolized droplet capture

Lee, U. N.; van Neel, T. L.; Lim, F. Y.; Khor, J. W.; He, J.; Vaddi, R. S.; Berthier, J.; Novosselov, I. V.; Theberge, A. B.; Berthier, E.

10.1101/2021.03.23.436614 — bioengineering — Posted on 2021-03-24

1197 Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment

Danis, C.; Dupre, E.; Zejneli, O.; Caillierez, R.; Arrial, A.; Begard, S.; Loyens, A.; Mortelecque, J.; Cantrelle, F.-X.; Hanoulle, X.; Rain, J.-C.; Colin, M.; Luc Buee, L.; Landrieu, I.

10.1101/2021.03.23.436266 — biochemistry — Posted on 2021-03-24

1198 Robustness of Collective Scenting in the Presence of Physical Obstacles

Nguyen, D. M. T.; Gharooni Fard, G.; Iuzzolino, M. L.; Peleg, O.

10.1101/2021.03.23.436715 — animal behavior and cognition — Posted on 2021-03-24

1199 Condensin DC spreads linearly and bidirectionally from recruitment sites to create loop-anchored TADs in C. elegans

Jimenez, D. S.; Kim, J.; Ragipani, B.; Zhang, B.; Street, L. A.; Kramer, M.; Albritton, S. E.; Winterkorn, L.; Ercan, S.

10.1101/2021.03.23.436694 — genomics — Posted on 2021-03-24

1200 Cell type-specific meQTL extends melanoma GWAS annotation beyond eQTL and informs melanocyte gene regulatory mechanisms

Zhang, T.; Choi, J.; Dilshat, R.; Einarsdottir, B. O.; Kovacs, M. A.; Xu, M.; Malasky, M.; Chowdhury, S.; Jones, K.; Bishop, D. T.; Goldstein, A. M.; Iles, M. M.; Landi, M. T.; Law, M. H.; Shi, J.; Steingrimsson, E.; Brown, K. M.

10.1101/2021.03.23.436704 — genetics — Posted on 2021-03-24

1201 Bayestrat: Population Stratification Correction Using Bayesian Shrinkage Prior for Genetic Association Studies

Liu, Z.; Turkmen, A.; Lin, S.

10.1101/2021.03.23.436705 — genetics — Posted on 2021-03-24

1202 DrosoPhyla: genomic resources for drosophilid phylogeny and systematics

Finet, C.; Kassner, V. A.; Carvalho, A. B.; Chung, H.; Day, J. P.; Delaney, E. K.; De Re, F. C.; Dufour, H. D.; Dupim, E.; Izumitani, H. F.; Gauterio, T. B.; Justen, J.; Katoh, T.; Kopp, A.; Koshikawa, S.; Longdon, B.; Loreto, E. L.; Nunes, M. D.; Raja, K. K.; Rebeiz, M.; Ritchie, M. G.; Saakyan, G.; Sneddon, T.; Teramoto, M.; Tyukmaeva, V.; Vanderlinde, T.; Wey, E. E.; Werner, T.; Williams, T. M.; Robe, L. J.; Toda, M. J.; Marletaz, F.

10.1101/2021.03.23.436709 — evolutionary biology — Posted on 2021-03-24

1203 Nasonia segmentation is regulated by an ancestral insect segmentation regulatory network also present in flies

Taylor, S.; Dearden, P.

10.1101/2021.03.23.436706 — developmental biology — Posted on 2021-03-24

1204 Machine learning models exploring characteristic single-nucleotide signatures in Yellow Fever Virus

Salgado, A.; Minardi, R.; Giovanetti, M.; Veloso, A.; Morais-Rodrigues, F.; Adelino, T.; Jesus, R.; Tosta, S.; Azevedo, V.; Lourenco, J.; Alcantara, L. C. J.

10.1101/2021.03.23.436688 — microbiology — Posted on 2021-03-24

1205 Transmission potential of Floridian Aedes aegypti mosquitoes for dengue virus serotype 4: Implications for estimating local dengue risk

Stephenson, C. J.; Coatsworth, H.; Kang, S.; Lednicky, J. A.; Dinglasan, R. R.

10.1101/2021.03.23.436716 — microbiology — Posted on 2021-03-24

1206 RNA Pol IV has antagonistic parent-of-origin effects on Arabidopsis endosperm

Satyaki, P. R. V.; Gehring, M.

10.1101/2021.03.24.436774 — plant biology — Posted on 2021-03-24

1207 Proteasome homeostasis is essential for a robust cauliflower mosaic virus infection

Hafren, A.; Uestuen, S.; Shukla, A.

10.1101/2021.03.24.436740 — plant biology — Posted on 2021-03-24

1208 Turning plants from passive to active material: FERONIA and microtubules independently contribute to mechanical feedback

Malivert, A.; Erguvan, O.; Chevallier, A.; Dehem, A.; Friaud, R.; Liu, M.; Martin, M.; Peyraud, T.; Hamant, O.; Verger, S.

10.1101/2021.03.24.436809 — plant biology — Posted on 2021-03-24

1209 A polyyne toxin produced by an antagonistic bacterium blinds and lyses a green microalga

Hotter, V.; Zopf, D.; Kim, H. J.; Silge, A.; Schmitt, M.; Aiyar, P.; Fleck, J.; Matthaeus, C.; Hniopek, J.; Yan, Q.; Loper, J.; Sasso, S.; Hertweck, C.; Popp, J.; Mittag, M.

10.1101/2021.03.24.436739 — plant biology — Posted on 2021-03-24

1210 Viability markers for determination of desiccation tolerance and critical stages during dehydration in Selaginella species

Alejo-Jacuinde, G.; Kean-Galeno, T.; Martinez-Gallardo, N.; Tejero-Diez, D.; Mehltreter, K.; Delano-Frier, J.; Oliver, M.; Simpson, J.; Herrera-Estrella, L. R.

10.1101/2021.03.23.436672 — plant biology — Posted on 2021-03-24

1211 Comparative Multiomic Analysis Reveals Low T Cell Infiltration as the Primary Feature of Tobacco Use in HPV(+) Oropharyngeal Cancer

Wahle, B. M.; Zolkind, P.; Ramirez, R.; Skidmore, Z. L.; Mazul, A.; Hayes, D. N.; Sandulache, V. C.; Thorstad, W. L.; Adkins, D.; Griffith, O. L.; Griffith, M.; Zevallos, J. P.

10.1101/2021.03.23.436478 — cancer biology — Posted on 2021-03-24

1212 The synergic role of actomyosin architecture and biased detachment in muscle energetics: insights in cross bridge mechanism beyond the lever-arm swing

Marcucci, L.; Fukunaga, H.; Yanagida, T.; Iwaki, M.

10.1101/2021.03.23.436693 — biophysics — Posted on 2021-03-24

1213 RNA-Ribo Explorer: interactive mining and visualisation of Ribosome profiling data

Paulet, D.; David, A.; RIVALS, E.

10.1101/2021.03.23.436679 — bioinformatics — Posted on 2021-03-24

1214 A comparison of rotation-based scores for gene set analysis

Caballe Mestres, A.; Berenguer Llergo, A.; Stephan-Otto Attolini, C.

10.1101/2021.03.23.436604 — bioinformatics — Posted on 2021-03-24

1215 Integrating transcription factor abundance with chromatin accessibility in human erythroid lineage commitment

Baskar, R.; Chen, A. F.; Favaro, P. M. B.; Reynolds, W.; Muller, F.; Borges, L.; Jiang, S.; Shin Park, H.; Kool, E. T.; Greenleaf, W.; Bendall, S. C.

10.1101/2021.03.23.436609 — genomics — Posted on 2021-03-24

1216 Quantitative single cell 5hmC sequencing reveals non-canonical gene regulation by non-CG hydroxymethylation

Fabyanic, E. B.; Hu, P.; Qiu, Q.; Berrios, K. N.; Flournoy, J.; Connolly, D. R.; Zhou, Z.; Kohli, R. M.; Wu, H.

10.1101/2021.03.23.434325 — genomics — Posted on 2021-03-24

1217 Tick hazard in the South Downs National Park (UK): species, distribution, key locations for future interventions, site density, habitats

Middleton, J.; Cooper, I.; Rott, A. S.

10.1101/2021.03.23.436533 — ecology — Posted on 2021-03-24

1218 Deep Learning Predicts Patterns of Cardiotoxicity in a High-Content Screen Using Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Grafton, F.; Ho, J.; Ranjbarvaziri, S.; Farshidfar, F.; Budan, A.; Steltzer, S.; Maddah, M.; Loewke, K. E.; Green, K.; Patel, S.; Hoey, T.; Mandegar, M. A.

10.1101/2021.03.23.436666 — cell biology — Posted on 2021-03-24

1219 miRador: a fast and precise tool for the prediction of plant miRNAs

Hammond, R. K.; Patel, P.; Gupta, P.; Meyers, B. C.

10.1101/2021.03.24.436803 — plant biology — Posted on 2021-03-24

1220 Translocation of chloroplast NPR1 to the nucleus in retrograde signaling for adaptive response to salt stress in tobacco

Park, K. Y.; Seo, S. Y.

10.1101/2021.03.24.436779 — plant biology — Posted on 2021-03-24

1221 Untangling the cell immune response dynamic for severe and critical cases of SARS-CoV-2 infection

Blanco-Rodriguez, R.; Du, X.; Hernandez Vargas, E. A.

10.1101/2021.03.23.436686 — biophysics — Posted on 2021-03-24

1222 3D visualization of SARS-CoV-2 infection and receptor distribution in Syrian hamster lung lobes display distinct spatial arrangements

Tomris, I.; Bouwman, K. M.; Adolfs, Y.; Noack, D.; van der Woude, R.; Herfst, S.; Boons, G.-J.; Haagmans, B.; Pasterkamp, R. J.; Rockx, B.; de Vries, R. P.

10.1101/2021.03.24.435771 — microbiology — Posted on 2021-03-24

1223 Isolation and Characterization of Cross-Neutralizing Coronavirus Antibodies from COVID-19+ Subjects

Jennewein, M.; MacCamey, A.; Akins, N.; Feng, J.; Homad, L.; Hurlburt, N.; Seydoux, E.; Wang, Y.-H.; Stuart, A. B.; Edara, V. V.; Floyd, K.; Vanderheiden, A.; Mascola, J. R.; Doria-Rose, N.; Wang, L.; Yang, E.; Chu, H.; Torres, J.; Ozorowski, G.; Ward, A.; Whaley, R.; Cohen, K.; Pancera, M.; McElrath, J.; Englund, J. A.; Finzi, A.; Suthar, M.; McGuire, A.; Stamatatos, L.

10.1101/2021.03.23.436684 — immunology — Posted on 2021-03-24

1224 B.1.526 SARS-CoV-2 variants identified in New York City are neutralized by vaccine-elicited and therapeutic monoclonal antibodies

Zhou, H.; Dcosta, B. M.; Samanovic, M. I.; Mulligan, M. J.; Landau, N. R.; Tada, T.

10.1101/2021.03.24.436620 — immunology — Posted on 2021-03-24

1225 Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2

Tummino, T. A.; Rezelj, V. V.; Fischer, B.; Fischer, A.; O'Meara, M. J.; Monel, B.; Vallet, T.; Zhang, Z.; Alon, A.; O'Donnell, H. R.; Lyu, J.; Schadt, H.; White, K. M.; Krogan, N. J.; Urban, L.; Shokat, K.; Kruse, A.; Garcia-Sastre, A.; Schwartz, O.; Moretti, F.; Vignuzzi, M.; Pognan, F.; Shoichet, B. K.

10.1101/2021.03.23.436648 — pharmacology and toxicology — Posted on 2021-03-24

1226 Effects of domestication on neophobia: A comparison between the domesticated Bengalese finch (Lonchura striata var. domestica) and its wild ancestor, the white-rumped munia (Lonchura striata)

Suzuki, K.; Ikebuchi, M.; Kagawa, H.; Koike, T.; Okanoya, K.

10.1101/2021.03.23.436696 — animal behavior and cognition — Posted on 2021-03-24

1227 Ezh2 mediates epigenetic regulation of osteoclastogenesis and bone remodeling in mice

Chen, J.-R.; Lazarenko, O. P.; Gai, D.; Li, C.; Blackburn, M. L.; Zhan, F.

10.1101/2021.03.24.436787 — developmental biology — Posted on 2021-03-24

1228 Heat-treated virus inactivation rate depends strongly on treatment procedure: illustration with SARS-CoV-2

Gamble, A.; Fischer, R. J.; Morris, D. H.; Yinda, K. C.; Munster, V. J.; Lloyd-Smith, J. O.

10.1101/2020.08.10.242206 — microbiology — Posted on 2021-03-24

1229 Neural markers of speech comprehension: measuring EEG tracking of linguistic speech representations, controlling the speech acoustics

Gillis, M.; Vanthornhout, J.; Simon, J. Z.; Francart, T.; Brodbeck, C.

10.1101/2021.03.24.436758 — neuroscience — Posted on 2021-03-24

1230 A phenomics approach for in vitro antiviral drug discovery

Rietdijk, J.; Tampere, M.; Pettke, A.; Georgiev, P.; Lapins, M.; Warpman Berglund, U.; Spjuth, O.; Puumalainen, M.-R.; Carreras-Puigvert, J.

10.1101/2021.01.13.423947 — pharmacology and toxicology — Posted on 2021-03-24

1231 A Fast High-Affinity Fluorescent Serotonin Biosensor Engineered from a Tick Lipocalin

Zhang, S.; Li, X.; Drobizhev, M.; Ai, H.

10.1101/2020.04.18.048397 — neuroscience — Posted on 2021-03-24

1232 E484K as an innovative phylogenetic event for viral evolution: Genomic analysis of the E484K spike mutation in SARS-CoV-2 lineages from Brazil

Ferrareze, P. A. G.; Franceschi, V. B.; Mayer, A. d. M.; Caldana, G. D.; Zimerman, R. A.; Thompson, C. E.

10.1101/2021.01.27.426895 — evolutionary biology — Posted on 2021-03-24

1233 An mRNA vaccine against SARS-CoV-2: Lyophilized, liposome-based vaccine candidate EG-COVID induces high levels of virus neutralizing antibodies

Hong, H. C.; Kim, K. S.; Park, S. A.; Chun, M. J.; Hong, E. Y.; Chung, S. W.; Kim, H. J.; Shin, B. G.; Cho, Y. J.; Braka, A.; Thangappan, J.; Jang, S.; Wu, S.; Kim, S.-H.

10.1101/2021.03.22.436375 — molecular biology — Posted on 2021-03-24

1234 The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection

10.1101/2021.03.22.436522 — microbiology — Posted on 2021-03-24

1235 Fatal COVID-19 ARDS associated with incomplete AEC1 differentiation from the transitional state without senescence or fibrosis

Ting, C.; Aspal, M.; Vaishampayan, N.; Huang, S. K.; Wang, F.; Farver, C.; Zemans, R. L.

10.1101/2021.01.12.426404 — pathology — Posted on 2021-03-24

1236 Microbial retention and resistances in stormwater quality improvement devices treating road runoff

Liguori, R.; Rommel, S. H.; Bengtsson-Palme, J.; Helmreich, B.; Wurzbacher, C.

10.1101/2021.01.12.426166 — microbiology — Posted on 2021-03-24

1237 The degree of polymerization and sulfation patterns in heparan sulfate are critical determinants of cytomegalovirus entry into host cells

Hasan, M.; Mitra, D.; Parmar, R.; Fassero, L. A.; Liang, Q.; Qiu, H.; Tiwari, V.; Sharp, J.; Wang, L.; Tandon, R.

10.1101/590463 — microbiology — Posted on 2021-03-24

1238 Functionnectome: a framework to analyse the contribution of brain circuits to fMRI

Nozais, V.; Forkel, S. J.; Foulon, C. J.; Petit, L.; Thiebaut de Schotten, M.

10.1101/2021.01.06.425574 — neuroscience — Posted on 2021-03-24

1239 The balance between toxic versus nontoxic microRNAs determines platinum sensitivity in ovarian cancer

Patel, M.; Wang, Y.; Bartom, E.; Dhir, R.; Nephew, K.; Matei, D.; Murmann, A.; Lengyel, E.; Peter, M. E.

10.1101/2021.01.24.427815 — cancer biology — Posted on 2021-03-24

1240 M1BP cooperates with CP190 to activate transcription at TAD borders and promote chromatin insulator activity

Bag, I.; Chen, S.; Rosin, L. F.; Chen, Y.; Liu, C.-Y.; Yu, G.-Y.; Lei, E. P.

10.1101/2020.10.27.357533 — genomics — Posted on 2021-03-24

1241 Learning when effort matters: Neural dynamics underlying updating and adaptation to changes in performance efficacy

Grahek, I.; Froemer, R.; Shenhav, A.

10.1101/2020.10.09.333310 — neuroscience — Posted on 2021-03-24

1242 Variations in Structural MRI Quality Significantly Impact Commonly-Used Measures of Brain Anatomy

Gilmore, A.; Buser, N. J.; Hanson, J. L.

10.1101/581876 — neuroscience — Posted on 2021-03-24

1243 Conjunctive spatial and idiothetic codes are topographically organized in the GABAergic cells of the lateral septum

van der Veldt, S.; Etter, G.; Sosa, F.; Mosser, C.-A.; Williams, S.

10.1101/2020.11.03.366849 — neuroscience — Posted on 2021-03-24

1244 Efficient masking of plant genomes by combining kmer counting and curated repeats

Contreras-Moreira, B.; Filippi, C. V.; Naamati, G.; Garcia Giron, C.; Allen, J. E.; Flicek, P.

10.1101/2021.03.22.436504 — genomics — Posted on 2021-03-24

1245 Response of whitefly to the wild tomato Solanum habrochaites

Li, F.; Dewer, Y.; Tian, J.; Li, D.; Qu, C.; Luo, C.

10.1101/2021.02.26.432993 — ecology — Posted on 2021-03-24

1246 Dimeric form of SARS-CoV-2 polymerase

Jochheim, F. A.; Tegunov, D.; Hillen, H. S.; Schmitzova, J.; Kokic, G.; Dienemann, C.; Cramer, P.

10.1101/2021.03.23.436644 — molecular biology — Posted on 2021-03-24

1247 Revisiting the role of Toxoplasma gondii ERK7 in the maintenance and stability of the apical complex

Soldati-Favre, D.; Dos Santos Pacheco, N.; Tosetti, N.; Krishnan, A.; Haase, R.

10.1101/2021.03.22.436543 — microbiology — Posted on 2021-03-24

1248 Identification and characterization of novel infection associated transcripts in macrophages

Arumugam, P.; Lodha, R.; Rao, v.

10.1101/2021.03.22.436546 — immunology — Posted on 2021-03-24

1249 Fungal Ice2p is in the same superfamily as SERINCs, restriction factors for HIV and other viruses

Alli-Balogun, G. O.; Levine, T. P.

10.1101/2021.01.08.425964 — bioinformatics — Posted on 2021-03-24

1250 When makes you unique: temporality of the human brain fingerprint

Van De Ville, D.; Farouj, Y.; Preti, M. G.; Liegeois, R.; Amico, E.

10.1101/2021.03.24.436733 — neuroscience — Posted on 2021-03-24

1251 Hearing loss is associated with delayed neural responses to continuous speech

Gillis, M.; Decruy, L.; Vanthornhout, J.; Francart, T.

10.1101/2021.01.21.427550 — neuroscience — Posted on 2021-03-24

1252 The proteome of remyelination is different from that of developmental myelination

Paes de Faria, J.; Azevedo, M. M.; Bausch-Fluck, D.; Seixas, A. I.; Domingues, H. S.; Monteiro, M. A.; Pedrioli, P. G.; Lopes, E.; Fernandes, R.; Zhao, C.; Franklin, R. J.; Wollscheid, B.; Relvas, J. B.; Montani, L.

10.1101/2021.03.24.436006 — neuroscience — Posted on 2021-03-24

1253 Powering electronic implants by high frequency volume conduction: in human validation

Minguillon, J.; Tudela-Pi, M.; Becerra-Fajardo, L.; Perera-Bel, E.; del-Ama, A. J.; Gil-Agudo, A.; Megia-Garcia, A.; Garcia-Moreno, A.; Ivorra, A.

10.1101/2021.03.15.435404 — bioengineering — Posted on 2021-03-24

1254 Eukaryotic rather than prokaryotic microbiomes change over seasons in rewetted fen peatlands

Wang, H.; Weil, M.; Zak, D.; Muench, D.; Guenther, A.; Jurasinski, G.; Blume-Werry, G.; Kreyling, J.; Urich, T.

10.1101/2020.02.16.951285 — microbiology — Posted on 2021-03-24

1255 Two Are Better Than One: Solving the Problem of Vertical Sound Source Localization via Binaural Integration of HRTFs

Oess, T.; Neumann, H.; Ernst, M. O.

10.1101/2020.09.10.291468 — neuroscience — Posted on 2021-03-24

1256 SOMDE: A scalable method for identifying spatially variable genes with self-organizing map

Hao, M.; Hua, K.; Zhang, X.

10.1101/2020.12.10.419549 — bioinformatics — Posted on 2021-03-24

1257 Spatially-explicit modeling improves empirical characterization of dispersal

Karisto, P.; Suffert, F.; Mikaberidze, A.

10.1101/789156 — ecology — Posted on 2021-03-24

1258 Integration of APSIM and PROSAIL models to develop more precise radiometric estimation of crop traits using deep learning

Chen, Q.; Zheng, B.; Chen, T.; Chapman, S.

10.1101/2021.02.02.429471 — ecology — Posted on 2021-03-24

1259 Membrane insertion of Cavin1 facilitates caveolae assembly

Liu, K.-c.; Pace, H.; Larsson, E.; Hossain, S.; Kabedev, A.; Mohan, J.; Bergstrom, C. A. S.; Schwieger, C.; Hubert, M.; Lundmark, R.

10.1101/2021.03.23.436578 — cell biology — Posted on 2021-03-24

1260 Histone H3 Clipping is a novel signature of Human Neutrophil Extracellular Traps

Tilley, D. O.; Abuabed, U.; Zimny Arndt, U.; Schmid, M.; Florian, S.; Jungblut, P. R.; Brinkmann, V.; Herzig, A.; Zychlinsky, A.

10.1101/2021.03.15.434949 — immunology — Posted on 2021-03-24

1261 Altered Effective Connectivity in Sensorimotor Cortices: a Novel Signature of Severity and Clinical Course in Depression

Ray, D.; Bezmaternykh, D.; Mel'nikov, M.; Friston, K. J.; Das, M.

10.1101/2021.03.14.435324 — neuroscience — Posted on 2021-03-24

1262 TRANSFER ENTROPY BASED CAUSALITY FROM HEAD MOTION TO EYE MOVEMENT

Lv, Z.; Xu, Q.; Schoeffmann, K.; Parkinson, S.

10.1101/2021.03.11.434910 — bioinformatics — Posted on 2021-03-24

1263 Genetics of resistance to common root rot (spot blotch), Fusarium crown rot, and sharp eyespot in wheat

Su, J.; Zhao, J.; Zhao, S.; Li, M.; Pang, S.; Chen, S.; Chen, F.; Zhen, W.; Kang, Z.; Wang, X.

10.1101/2020.07.30.228932 — genetics — Posted on 2021-03-24

1264 RT-QuIC detection of CWD prion seeding activity in white-tailed deer muscle tissues

Li, M.; Schwabenlander, M. D.; Rowden, G. R.; Schefers, J. M.; Seelig, D.; Larsen, P. A.

10.1101/2021.03.22.436515 — molecular biology — Posted on 2021-03-24

1265 Exploitation of the genetic variability in the genotype of Egyptian Wheat by studding Molecular Markers, Molecular Docking and Nano Composites. Regulation of leaf and stem rust

Omar, H. S.; Reyad, N. E. H. A.; Sedeek, M. S.; Shamkh, I. M.

10.1101/2021.03.18.436051 — molecular biology — Posted on 2021-03-24

1266 Revealing the inherent susceptibility of pathogenic bacteria to magnetic hyperthermia

Ghosh, D.; Kaushik, S.; Thomas, J.; Panwar, V.; Murugesan, P.; Chopra, V.; Salaria, N.; Singh, R.; Roy, H. S.; Kumar, R.; Gautam, V.

10.1101/2021.02.03.429514 — microbiology — Posted on 2021-03-24

1267 Development of early postnatal inhibitory function in the mouse medial prefrontal and primary somatosensory cortex

Kalemaki, K.; Xu, X.; Velli, A.; Christodoulou, O.; Denaxa, M.; Hanganu-Opatz, I. L.; Sidiropoulou, K.; Karagogeos, D.

10.1101/2020.01.21.913913 — neuroscience — Posted on 2021-03-24

1268 Hippocampal replay reflects specific past experiences rather than a plan for subsequent choice

Gillespie, A. K.; Astudillo Maya, D. A.; Denovellis, E. L.; Liu, D. F.; Kastner, D. B.; Coulter, M. E.; Roumis, D. K.; Eden, U. T.; Frank, L. M.

10.1101/2021.03.09.434621 — neuroscience — Posted on 2021-03-24

1269 Refinement of corticospinal neuron activity during skilled motor learning

Serradj, N.; Marino, F.; Moreno-Lopez, Y.; Agger, S.; Sloan, A. M.; Hollis, E. R.

10.1101/2021.03.22.436415 — neuroscience — Posted on 2021-03-24

1270 Stabilization of Brain Network Dynamics during Childhood and Adolescence is Associated with Gene Expressions

Lei, T.; Liao, X.; Chen, X.; Zhao, T.; Xu, Y.; Xia, M.; Zhang, J.; Sun, X.; Wei, Y.; Men, W.; Wang, Y.; Hu, M.; Zhao, G.; Du, B.; Wu, Q.; Tan, S.; Gao, J.; Qin, S.; Tao, S.; Dong, Q.; He, Y.

10.1101/2021.03.03.433828 — neuroscience — Posted on 2021-03-24

1271 MEYE: Web-app for translational and real-time pupillometry

Mazziotti, R. M.; Carrara, F.; Viglione, A.; Lupori, L.; Lo Verde, L.; Benedetto, A.; Ricci, G.; Sagona, G.; Amato, G.; Pizzorusso, T.

10.1101/2021.03.09.434438 — neuroscience — Posted on 2021-03-24

1272 The radish Ogura fertility restorer impedes translation elongation along its cognate CMS-causing mRNA

Wang, C.; Lezhneva, L.; Arnal, N.; Quadrado, M.; Mireau, H.

10.1101/2021.03.17.435859 — plant biology — Posted on 2021-03-24

1273 Self-ubiquitination of a pathogen type-III effector traps and blocks the autophagy machinery to promote disease

Leong, J. X.; Raffeiner, M.; Spinti, D.; Langin, G.; Franz-Wachtel, M.; Guzman, A. R.; Kim, J.-G.; Pandey, P.; Minina, A. E. A.; Macek, B.; Hafren, A.; Bozkurt, T. O.; Mudgett, M. B.; Boernke, F.; Hofius, D.; Uestuen, S.

10.1101/2021.03.17.435853 — plant biology — Posted on 2021-03-24

1274 SPIRO - the automated Petri plate imaging platform designed by biologists, for biologists

Ohlsson, J. A.; Leong, J. X.; Elander, P. H.; Dauphinee, A. N.; Ballhaus, F.; Johansson, J.; Lommel, M.; Hofmann, G.; Betner, S.; Sandgren, M.; Schumacher, K.; Bozhkov, P. V.; Minina, A. E. A.

10.1101/2021.03.15.435343 — plant biology — Posted on 2021-03-24

1275 The M1 aminopeptidase NPEPPS is a novel regulator of cisplatin sensitivity

Jones, R. T.; Goodspeed, A.; Akbarzadeh, M. C.; Scholtes, M.; Vekony, H.; Jean, A.; Tilton, C. B.; Orman, M. V.; Joshi, M.; Laajala, T. D.; Javaid, M.; Clambey, E. T.; Layer, R.; Parker, S.; Mahmoudi, T.; Zuiverloon, T.; Theodorescu, D.; Costello, J. C.

10.1101/2021.03.04.433676 — cancer biology — Posted on 2021-03-24

1276 Analysis of immune subtypes across the epithelial-mesenchymal plasticity spectrum

Chakraborty, P.; Chen, E.; McMullen, I.; Armstrong, A. J.; Jolly, M. K.; Somarelli, J. A.

10.1101/2021.03.22.436535 — cancer biology — Posted on 2021-03-24

1277 Programmed mechano-chemical coupling in reaction-diffusion active matter

Senoussi, A.; Galas, J.-C.; Estevez-Torres, A.

10.1101/2021.03.13.435232 — biophysics — Posted on 2021-03-24

1278 Predicting TCR-epitope Binding Specificity Using Deep Metric Learning and Multimodal Learning

Luu, A.; Leistico, J. R.; Miller, T.; Kim, S.; Song, J. S.

10.1101/2021.03.19.436191 — bioinformatics — Posted on 2021-03-24

1279 Nestmate recognition of early brood in ants

de Fouchier, A.; Leroy, C.; Khila, A.; d'Ettorre, P.

10.1101/2021.03.17.435807 — animal behavior and cognition — Posted on 2021-03-24

1280 A comprehensive survey of developmental programs reveals a dearth of tree-like lineage graphs and ubiquitous regeneration

Mani, S.; Tlusty, T.

10.1101/843888 — developmental biology — Posted on 2021-03-24

1281 Cell cycle-independent integration of stress signals promotes Non-G1/G0 quiescence entry

Arguello-Miranda, O.; Marchand, A.; Kennedy, T.; Russo, M. A.; Noh, J.

10.1101/2021.03.13.434817 — cell biology — Posted on 2021-03-24

1282 Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes

Devoucoux, M.; Khelifi, G.; Fort, V.; Bourriquen, G.; Hussein, S. M. I.; Cote, J.

10.1101/2021.03.08.434474 — molecular biology — Posted on 2021-03-24

1283 PRSS2 promotes tumor growth and progression by repressing Tsp-1 in the tumor microenvironment via binding to LRP1

10.1101/2021.03.23.436667 — cancer biology — Posted on 2021-03-23

1284 Molecular phylogeny of Puerto Rico Bank dwarf geckos (Squamata: Sphaerodactylidae: Sphaerodactylus)

Reynolds, R. G.; Miller, A. H.; Revell, L. J.; RIOS-FRANCESCHI, A.; Huffine, C. A.; Fredette, J.; Angeli, N. F.; VEGA-CASTILLO, S. I.; PUENTE-ROLON, A. R.

10.1101/2021.03.23.436310 — evolutionary biology — Posted on 2021-03-23

1285 Spatial heterogeneity enhance robustness of large multi-species ecosystems

Pettersson, S. M.; Nilsson Jacobi, M.

10.1101/2021.03.23.436582 — ecology — Posted on 2021-03-23

1286 Generation of functional ciliates cholangiocytes from human pluripotent stem cells

Ogawa, M.; Jiang, J.-X.; Xia, S.; Yang, D.; Ding, A.; Laselva, O.; Chin, S.; Hernandez, M.; Cui, C.; Higuchi, Y.; Suemizu, H.; Dorrell, C.; Grompe, M.; Bear, C.; Keller, G.; Ogawa, S.

10.1101/2021.03.23.436530 — cell biology — Posted on 2021-03-23

1287 Antimicrobial Resistance and Genomic Characterization of Salmonella Dublin Isolates in Cattle from the United States.

Srednik, M.; Lantz, K.; Hicks, J. A.; Morningstar-Shaw, B. R.; Mackie, T. A.; Schlater, L. K.

10.1101/2021.03.23.436584 — microbiology — Posted on 2021-03-23

1288 A deep-sea sulfate reducing bacterium directs the formation of zero-valent sulfur via sulfide oxidation

Liu, R.; Shan, Y.; Xi, S.; Zhang, X.; Sun, C.

10.1101/2021.03.23.436689 — microbiology — Posted on 2021-03-23

1289 Prostaglandin E2 induction by cytosolic Listeria monocytogenes in phagocytes is necessary for optimal T-cell priming

McDougal, C. E.; Morrow, Z. T.; Kim, S.; Carter, D.; Stevenson, D. M.; Amador-Noguez, D.; Miller, M. J.; Sauer, J.-D.

10.1101/2021.03.23.436585 — immunology — Posted on 2021-03-23

1290 Plant immune system activation is necessary for efficient interaction with auxin secreting beneficial bacteria

Tzipilevich, E.; Benfey, P. N.

10.1101/2021.03.23.436641 — plant biology — Posted on 2021-03-23

1291 Mechanical influences on in silico tumor evolution

Rosenbauer, J.; Berghoff, M.; Glazier, J. A.; Schug, A.

10.1101/2021.03.23.436580 — cancer biology — Posted on 2021-03-23

1292 Avidity observed between a bivalent inhibitor and an enzyme monomer with a single active site

Lacham-Hartman, S.; Shmidov, Y.; Radisky, E.; Bitton, R. B.; Lukatsky, D.; Papo, N.

10.1101/2021.03.23.436583 — biochemistry — Posted on 2021-03-23

1293 Mast cell function in prostate inflammation, fibrosis, and smooth muscle cell dysfunction

Pattabiraman, G.; Bell-Cohn, A. J.; Murphy, S. F.; Mazur, D. J.; Schaeffer, A. J.; Thumbikat, P.

10.1101/2021.03.23.436678 — cell biology — Posted on 2021-03-23

1294 Genome-wide Association Study of Pancreatic Fat: The Multiethnic Cohort Adiposity Phenotype Study

Streicher, S.; Lim, U.; Park, S. L.; Li, Y.; Sheng, X.; Hom, V.; Xia, L.; Pooler, L.; Shepherd, J.; Loo, L. W.; Darst, B. F.; Highland, H. M.; Polfus, L. M.; Bogumil, D.; Ernst, T.; Buchthal, S.; Franke, A. A.; Setiawan, V. W.; Tiirikainen, M.; Wilkens, L. R.; Haiman, C. A.; Stram, D. O.; Cheng, I.; Le Marchand, L.

10.1101/2021.03.23.436581 — cell biology — Posted on 2021-03-23

1295 Sexually divergent cortical control of affective-autonomic integration

Wallace, T.; Schaeuble, D.; Pace, S. A.; Schackmuth, M. K.; Hentges, S. T.; Chicco, A. J.; Myers, B.

10.1101/2020.09.29.319210 — neuroscience — Posted on 2021-03-23

1296 The SARS-CoV-2 replication-transcription complex is a priority target for broad-spectrum pan-coronavirus drugs

Yazdani, S.; De Maio, N.; Ding, Y.; Shahani, V.; Goldman, N.; Schapira, M.

10.1101/2021.03.23.436637 — pharmacology and toxicology — Posted on 2021-03-23

1297 Impact of increased membrane realism on conformational sampling of proteins

Weigle, A. T.; Carr, M.; Shukla, D.

10.1101/2021.03.23.436674 — biophysics — Posted on 2021-03-23

1298 BubbleGun: Enumerating Bubbles and Superbubbles in Genome Graphs

Dabbaghie, F.; Ebler, J.; Marschall, T.

10.1101/2021.03.23.436631 — bioinformatics — Posted on 2021-03-23

1299 High resolution ultrasonic neural modulation observedvia in vivo two-photon calcium imaging

Cheng, Z.; Wang, C.; Wei, B.; Gan, W.; Zhou, Q.; Cui, M.

10.1101/2021.03.23.436645 — bioengineering — Posted on 2021-03-23

1300 Innate visual attraction in wood ants is a hardwired behaviour seen across different motivational and ecological contexts

Buehlmann, C.; Graham, P.

10.1101/2021.01.29.428794 — animal behavior and cognition — Posted on 2021-03-23

1301 Genomes of Wolbachia endosymbionts from the human filarial parasites Mansonella perstans and Mansonella ozzardi

Sinha, A.; Li, Z.; Poole, C. B.; Ettwiller, L.; Lima, N. F.; Ferreira, M. U.; Fombad, F. F.; Wanji, S.; Carlow, C.

10.1101/2021.03.23.436630 — genomics — Posted on 2021-03-23

1302 Comparing divergence landscapes from reduced-representation and whole-genome re-sequencing in the yellow-rumped warbler (Setophaga coronata) species complex

Szarmach, S.; Brelsford, A.; Witt, C. C.; Toews, D.

10.1101/2021.03.23.436663 — evolutionary biology — Posted on 2021-03-23

1303 Capturing and analyzing pattern diversity: an example using the melanistic spotted patterns of leopard geckos

Glimm, T.; Kiskowski, M.; Moreno, N.; Chiari, Y.

10.1101/2021.03.23.436685 — developmental biology — Posted on 2021-03-23

1304 Characterization of a novel amastin-like surface protein (ALSP) of Leishmania donovani, a probable lipase

Biswas, B.; Laha, B.; Ghosh, M.

10.1101/2020.07.23.218107 — molecular biology — Posted on 2021-03-23

1305 Innate triggering and antiviral effector functions of activin A

Al-Hourani, K.; Ramamurthy, N.; Marchi, E.; Eichinger, R. M.; Lee, L. N.; Fabris, P.; Klenerman, P.; Drakesmith, A. H.

10.1101/2021.03.23.436626 — immunology — Posted on 2021-03-23

1306 Mycobacterium tuberculosis modifies cell wall carbohydrates during biofilm growth with a concomitant reduction in complement activation

Keating, T.; Lethbridge, S.; Thomas, S. R.; Alderwick, L. J.; Taylor, S. C.; Bacon, J.

10.1101/2021.03.23.436651 — immunology — Posted on 2021-03-23

1307 The cue-reactivity paradigm: An ensemble of networks driving attention and cognition when viewing drug and natural reward-related stimuli

Hill-Bowen, L. D.; Riedel, M. C.; Poudel, R.; Salo, T.; Flannery, J. S.; Camilleri, J. A.; Eickhoff, S. B.; Laird, A. R.; Sutherland, M. T.

10.1101/2020.02.26.966549 — neuroscience — Posted on 2021-03-23

1308 A hierarchy of linguistic predictions during natural language comprehension

Heilbron, M.; Armeni, K.; Schoffelen, J.-M.; Hagoort, P.; de Lange, F. P.

10.1101/2020.12.03.410399 — neuroscience — Posted on 2021-03-23

1309 Insular cortex corticotropin-releasing factor integrates stress signaling with social decision making.

Rieger, N. S.; Varela, J. A.; Ng, A. J.; Granata, L.; Djerdjaj, A.; Brenhouse, H. C.; Christianson, J. P.

10.1101/2021.03.23.436680 — neuroscience — Posted on 2021-03-23

1310 Anterior claustrum cells are responsive during behavior but not passive sensory stimulation

Ollerenshaw, D. R.; Davis, J.; McBride, E. G.; Shelton, A.; Koch, C.; Olsen, S. R.

10.1101/2021.03.23.436687 — neuroscience — Posted on 2021-03-23

1311 Tractography dissection variability: what happens when 42 groups dissect 14 white matter bundles on the same dataset?

10.1101/2020.10.07.321083 — neuroscience — Posted on 2021-03-23

1312 Heritable functional architecture in human visual cortex

Alvarez, I.; Finlayson, N. J.; Ei, S.; de Haas, B.; Greenwood, J. A.; Schwarzkopf, D. S.

10.1101/2020.05.04.077545 — neuroscience — Posted on 2021-03-23

1313 Prediction Errors Disrupt Hippocampal Representations and Update Episodic Memories

Sinclair, A. H.; Manalili, G. M.; Brunec, I. K.; Adcock, R. A.; Barense, M. D.

10.1101/2020.09.29.319418 — neuroscience — Posted on 2021-03-23

1314 Species richness determines C. difficile invasion outcome in synthetic human gut communities

Hromada, S.; Clark, R. L.; Qian, Y.; Watson, L.; Safdar, N.; Venturelli, O. S.

10.1101/2021.03.23.436677 — systems biology — Posted on 2021-03-23

1315 Chloroplasts alter their morphology and accumulate at the pathogen interface during infection by Phytophthora infestans

Savage, Z.; Duggan, C.; Toufexi, A.; Pandey, P.; Liang, Y.; Segretin, M. E.; Yuen, L. H.; Gaboriau, D. C. A.; Leary, A. Y.; Tumtas, Y.; Khandare, V.; Ward, A. D.; Botchway, S. W.; Bateman, B. C.; Pan, I.; Schattat, M.; Sparkes, I.; Bozkurt, T. O.

10.1101/516443 — plant biology — Posted on 2021-03-23

1316 DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas (PanNECs) and pancreatic neuroendocrine tumors (PanNETs)

10.1101/2020.06.12.146811 — cancer biology — Posted on 2021-03-23

1317 PIMBA: a PIpeline for MetaBarcoding Analysis

Oliveira, R. R. M.; Silva, R. L. S.; Nunes, G. L.; Oliveira, G.

10.1101/2021.03.23.436646 — bioinformatics — Posted on 2021-03-23

1318 ACTIVA: realistic single-cell RNA-seq generation with automatic cell-type identification using introspective variational autoencoders

Heydari, A. A.; Davalos, O. A.; Zhao, L.; Hoyer, K. K.; Sindi, S. S.

10.1101/2021.01.28.428725 — bioinformatics — Posted on 2021-03-23

1319 Genetic analysis of coronary artery disease using tree-based automated machine learning informed by biology-based feature selection

Manduchi, E.; Le, T. T.; Fu, W.; Moore, J. H.

10.1101/2021.03.23.436652 — bioinformatics — Posted on 2021-03-23

1320 Cation and anion channelrhodopsins: Sequence motifs and taxonomic distribution

Govorunova, E. G.; Sineshchekov, O. A.; Li, H.; Wang, Y.; Brown, L. S.; Palmateer, A.; Melkonian, M.; Cheng, S.; Carpenter, E.; Patterson, J.; Wong, G. K.-S.; Spudich, J. L.

10.1101/2021.03.23.436664 — biochemistry — Posted on 2021-03-23

1321 Crotamine as a vehicle for non-viral gene delivery for Pompe disease

Martiniuk, F.; Mack, A.; Martiniuk, J.; Karpel, R.; Meinke, P.; Schoser, B.; Wu, F.; Tchou-Wong, K.-M.

10.1101/2021.03.23.436632 — genetics — Posted on 2021-03-23

1322 The developmental hourglass model is applicable to the spinal cord

Mukaigasa, K.; Sakuma, C.; Yaginuma, H.

10.1101/2021.03.08.434342 — evolutionary biology — Posted on 2021-03-23

1323 Root carbon interaction with soil minerals is dynamic, leaving a legacy of microbially-derived residues

Neurath, R. A.; Pett-Ridge, J.; Chu-Jacoby, I.; Herman, D. J.; Whitman, T.; Nico, P. S.; Lipton, A. S.; Kyle, J.; Tfaily, M. M.; Thompson, A.; Firestone, M. K.

10.1101/2021.03.23.436628 — ecology — Posted on 2021-03-23

1324 Beta-arrestin-mediated Angiotensin II type 1 Receptor Activation Promotes Pulmonary Vascular Remodeling in Pulmonary Hypertension

Ma, Z.; Viswanathan, G.; Sellig, M. T.; Jassal, C. S.; Choi, I.; Xiong, X.; Nazo, N. M.; Rajagopal, S.

10.1101/2021.03.23.436676 — molecular biology — Posted on 2021-03-23

1325 Capsid Proteins are Necessary for Replication of a Parvovirus

Labadie, T.; Garcia, D.; Mutuel, D.; Ogliastro, M.; Cambray, G.

10.1101/2020.04.06.028852 — microbiology — Posted on 2021-03-23

1326 Multiple lineages of Streptomyces produce antimicrobials within passalid beetle galleries across eastern North America

Pessotti, R. d. C.; Hansen, B. L.; Reaso, J. N.; Ceja-Navarro, J. A.; El-Hifnawi, L.; Brodie, E. L.; Traxler, M. F.

10.1101/2020.12.02.394189 — microbiology — Posted on 2021-03-23

1327 FECAL MICROBIOME OF CHILDREN WITH NOROVIRUS GASTROENTERITIS

Hernandez, J. M.; Junior, E. C. S.; Almeida, G. B. S.; Portela, A. C. R.; Lucena, M. S. S.; Cardoso, J. F.; Reymao, T. K. A.; Lima, C. P. S.; Nunes, M. R. T.; Teixeira, D. M.; Siqueira, J. A. M.; Gabbay, Y. B.; Silva, L. D.

10.1101/2021.03.23.436635 — microbiology — Posted on 2021-03-23

1328 Clonal dissection of immunodominance and cross-reactivity of the CD4+ T cell response to SARS-CoV-2

Low, J. S.; Vaqueirinho, D.; Mele, F.; Foglierini, M.; Perotti, M.; Jarrossay, D.; Jovic, S.; Terrot, T.; Franzetti Pellanda, A.; Biggiogero, M.; Garzoni, C.; Ferrari, P.; Ceschi, A.; Lanzavecchia, A.; Cassotta, A.; Sallusto, F.

10.1101/2021.03.23.436642 — immunology — Posted on 2021-03-23

1329 Identification, crystallization and epitope determination of public TCR shared and expanded in COVID-19 patients

Lu, X.; Hosono, Y.; Ishizuka, S.; Nagae, M.; Ishikawa, E.; Motooka, D.; Ozaki, Y.; Sax, N.; Shinnakasu, R.; Inoue, T.; Onodera, T.; Matsumura, T.; Shinkai, M.; Sato, T.; Nakamura, S.; Mori, S.; Kanda, T.; Nakayama, E. E.; Shioda, T.; Kurosaki, T.; Arase, H.; Yamashita, K.; Takahashi, Y.; Yamasaki, S.

10.1101/2021.03.23.436573 — immunology — Posted on 2021-03-23

1330 Spatial relations trigger visual binding of people

Adibpour, P.; Hochmann, J.-R.; Papeo, L.

10.1101/2020.10.01.322198 — neuroscience — Posted on 2021-03-23

1331 Spiking recurrent neural networks represent task-relevant neural sequences in rule-dependent computation

Xue, X.; Halassa, M. M.; Chen, Z. S.

10.1101/2021.01.21.427464 — neuroscience — Posted on 2021-03-23

1332 fMRIflows: a consortium of fully automatic univariate and multivariate fMRI processing pipelines

Notter, M. P.; Herholz, P.; Da Costa, S.; Gulban, O. F.; Isik, A. I.; Murray, M. M.

10.1101/2021.03.23.436650 — neuroscience — Posted on 2021-03-23

1333 Neurite growth kinetics regulation through hydrostatic pressure in a novel triangle-shaped neurofluidic system

Maisonneuve, B. G. C.; Batut, A.; Varela, C.; Vieira, J.; Gleyzes, M.; Rontard, J.; Larramendy, F.; Honegger, T.

10.1101/2021.03.23.436675 — neuroscience — Posted on 2021-03-23

1334 Cholecystokinin 1 Receptor (Cck1R) Normalizes mTORC1 signaling and is Protective to Purkinje cells in SCA Mice

Wozniak, E. A. L.; Chen, Z.; Paul, S.; Yang, P.; Figueroa, K. P.; Tschumperlin, T.; Berken, M.; Ingram, M.; Henzler, C.; Pulst, S. M.; Orr, H. T.

10.1101/2021.02.16.431490 — neuroscience — Posted on 2021-03-23

1335 The lncRNA MARS modulates the epigenetic reprogramming of the marneral cluster in response to ABA

Roule, T.; Ariel, F.; Hartmann, C.; Hussain, N.; Benhamed, M.; Gutierrez-Marcos, J.; Crespi, M.; Blein, T.

10.1101/2020.08.10.236562 — plant biology — Posted on 2021-03-23

1336 Jurassic NLR: conserved and dynamic evolutionary features of the atypically ancient immune receptor ZAR1

Adachi, H.; Sakai, T.; Kourelis, J.; Gonzalez Hernandez, J. L.; Maqbool, A.; Kamoun, S.

10.1101/2020.10.12.333484 — plant biology — Posted on 2021-03-23

1337 Ribosome profiling elucidates differential gene expression in bundle sheath and mesophyll cells in maize

Chotewutmontri, P.; Barkan, A.

10.1101/2020.12.15.422948 — plant biology — Posted on 2021-03-23

1338 Interplay between intrinsic reprogramming potential and microenvironment controls neuroblastoma cell plasticity and identity

Thirant, C.; Peltier, A.; Durand, S.; Kramdi, A.; Louis-Brennetot, C.; Pierre-Eugene, C.; Costa, A.; Grelier, A.; Zaidi, S.; Gruel, N.; Jimenez, I.; Lapouble, E.; Pierron, G.; Brisse, H.; Gauthier, A.; Freneaux, P.; Grossetete-Lalami, S.; Baudrin, L. G.; Raynal, V.; Baulande, S.; Bellini, A.; Bhalshankar, J.; Carcaboso, A. M.; Geoerger, B.; Surdez, D.; Rohrer, H.; Boeva, V.; Schleiermacher, G.; Delattre, O.; Janoueix-Lerosey, I.

10.1101/2021.01.07.425710 — cancer biology — Posted on 2021-03-23

1339 Application of an integrated computational antibody engineering platform to design SARS-CoV-2 neutralizers

Riahi, S.; Lee, J. H.; Wei, S.; Cost, R.; Masiero, A.; Prades, C.; Olfati-Saber, R.; Wendt, M.; Park, A.; Qiu, Y.; Zhou, Y.

10.1101/2021.03.23.436613 — bioengineering — Posted on 2021-03-23

1340 Investigating post-breeding moult locations and diets of Common Guillemots (Uria aalge) in the North Sea using stable isotope analyses

Christie, A. P.

10.1101/2020.09.01.276857 — ecology — Posted on 2021-03-23

1341 Neutralization of European, South African, and United States SARS-CoV-2 mutants by a human antibody and antibody domains

Sun, Z.; Kim, A.; Sobolewski, M. D.; Enick, N.; Chen, C.; Adams, C.; Jacobs, J. L.; McCormick, K. D.; Mellors, J. W.; Dimitrov, D. S.; Li, W.

10.1101/2021.03.22.436481 — immunology — Posted on 2021-03-23

1342 A comparison of approaches to scaffolding multiple regions along the 16S rRNA gene for improved resolution

Debelius, J. W.; Robeson, M.; Hugerth, L. W.; Boulund, F.; Ye, W.; Engstrand, L.

10.1101/2021.03.23.436606 — bioinformatics — Posted on 2021-03-23

1343 Additive manufactured scaffolds for bone tissue engineering: physical characterization of thermoplastic composites with functional fillers

Sinha, R.; Sanchez, A.; Camara Torres, M.; Uriszar-Aldaca, I. C.; Calore, A. R.; Harings, J.; Gambardella, A.; Ciccarelli, L.; Vanzanella, V.; Sisani, M.; Scatto, M.; Wendelbo, R.; Perez, S.; Villanueva, S.; Matanza, A.; Patelli, A.; Grizzuti, N.; Mota, C.; Moroni, L.

10.1101/2021.03.23.436548 — bioengineering — Posted on 2021-03-23

1344 Bioinformatic analysis deciphers the molecular toolbox in the endophytic/pathogenic behaviour in F. oxysporum f. sp. vanillae - V. planifolia Jacks interaction

Solano De la Cruz, M. T.; Escobar Hernandez, E. E.; Arciniega Gonzalez, J. A.; Rueda Zozaya, R. D. P.; Luna Rodriguez, M.; Adame Garcia, J.

10.1101/2021.03.23.436347 — genomics — Posted on 2021-03-23

1345 In vivo tissue-specific chromatin profiling in Drosophila melanogaster using GFP-tagged nuclei

Jauregui-Lozano, J.; Bakhle, K.; Weake, V. M.

10.1101/2021.03.23.436625 — genomics — Posted on 2021-03-23

1346 A Genome-Phenome Association study in native microbiomes identifies a mechanism for cytosine modification in DNA and RNA

Yang, W.; Lin, Y.-C.; Johnson, W.; Dai, N.; Wiegele, P.; Lee, Y.-J.; Correa, I. R.; Ettwiller, L.

10.1101/2021.03.23.436658 — genomics — Posted on 2021-03-23

1347 Two promoters integrate multiple enhancer inputs to drive wild-type knirps expression in the D. melanogaster embryo

Li, L.; Waymack, R.; Elabd, M.; Wunderlich, Z.

10.1101/2021.03.23.436657 — developmental biology — Posted on 2021-03-23

1348 DNA replication during acute MEK inhibition drives acquisition of resistance through amplification of the BRAF oncogene

Channathodiyil, P.; Segonds-Pichon, A.; Smith, P. D.; Cook, S. J.; Houseley, J.

10.1101/2021.03.23.436572 — molecular biology — Posted on 2021-03-23

1349 Perturbation of ribosomal subunits dynamics by inhibitors of tRNA translocation

Belardinelli, R.; Sharma, H.; Peske, F.; Rodnina, M. V.

10.1101/2021.03.23.436553 — molecular biology — Posted on 2021-03-23

1350 Overexpression-based detection of translatable circular RNAs is vulnerable to coexistent linear byproducts

Jiang, Y.; Chen, X.; Zhang, W.

10.1101/2021.03.23.433163 — molecular biology — Posted on 2021-03-23

1351 Antibacterial activity of Balanites aegyptiaca Oil Extract on Staphylococcus aureus and Escherichia coli

Khanam, S.; Galadima, F. Z.

10.1101/2021.03.23.436600 — microbiology — Posted on 2021-03-23

1352 Synergy of culture-dependent molecular identification and whole-community metabarcode sequencing for characterizing the microbiota of arable crop residues

Laval, V.; Kerdraon, L.; Barret, M.; Liabot, A.-L.; Marais, C.; Boudier, B.; Balesdent, M.-H.; Fischer-Le Saux, M.; Suffert, F.

10.1101/2021.03.23.436452 — microbiology — Posted on 2021-03-23

1353 New SARS-CoV-2 lineages could evade CD8+ T-cells response

Pretti, M. A. M.; Galvani, R. G.; Farias, A. S.; Boroni, M.

10.1101/2021.03.09.434584 — immunology — Posted on 2021-03-23

1354 Decoding brain states on the intrinsic manifold of human brain dynamics across wakefulness and sleep

Rue-Queralt, J.; Stevner, A.; Tagliazucchi, E.; Laufs, H.; Kringelbach, M. L.; Deco, G.; Atasoy, S.

10.1101/2021.03.23.436551 — neuroscience — Posted on 2021-03-23

1355 Measuring splash-dispersal of a major wheat pathogen in the field

Karisto, P.; Suffert, F.; Mikaberidze, A.

10.1101/2021.03.23.436423 — plant biology — Posted on 2021-03-23

1356 Moonlighting adenylyl cyclases in plants: an Arabidopsis thaliana 9-cis-epoxycarotenoid dioxygenase as point in case

Al-Younis, I.; Wong, A.; Moosa, B.; Kwiatkowski, M.; Jaworski, K.; Gehring, C.

10.1101/2021.03.23.436544 — plant biology — Posted on 2021-03-23

1357 The fern CYPome: Fern-specific cytochrome P450 family involved in convergent evolution of chemical defense.

Thodberg, S.; Hansen, C. C.; Takos, A. M.; Picmanova, M.; Moller, B. L.; Nelson, D. R.; Neilson, E. H. J.

10.1101/2021.03.23.436569 — plant biology — Posted on 2021-03-23

1358 A short ERK5 isoform modulates nucleocytoplasmic shuttling of active ERK5 and associates with poor survival in breast cancer

Miranda, M. S.; Saunus, J. M.; Akgül, S.; Moradi Marjaneh, M.; Kutasovic, J. R.; Shi, W.; Chatterjee, O.; Casciello, F.; Rozali, E.; Handoko, H. Y.; Wiegmans, A. P.; Liu, T.; Lee, J. S.; Day, B. W.; Edwards, S.; French, J. D.; McCart Reed, A. E.; Chenevix-Trench, G.; Khanna, K. K. D.; Simpson, P. T.; Lakhani, S. R.; Al-Ejeh, F.

10.1101/2021.03.23.436061 — cancer biology — Posted on 2021-03-23

1359 SPECT/CT imaging, biodistribution and radiation dosimetry of a 177Lu-DOTA-integrin αvβ6 cystine knot peptide in a pancreatic cancer xenograft model

Sachindra, S.; Hellberg, T.; Exner, S.; Prasad, S.; Beindorff, N.; Rogalla, S.; Kimura, R.; Gambhir, S. S.; Wiedenmann, B.; Groetzinger, C.

10.1101/2021.03.23.436654 — cancer biology — Posted on 2021-03-23

1360 Comparative genome analysis using sample-specific string detection in accurate long reads

Khorsand, P.; Denti, L.; Bonizzoni, P.; Chikhi, R.; Hormozdiari, F.

10.1101/2021.03.23.436571 — bioinformatics — Posted on 2021-03-23

1361 Pan-genomic Matching Statistics for Targeted Nanopore Sequencing

Ahmed, O.; Rossi, M.; Kovaka, S.; Schatz, M.; Gagie, T.; Boucher, C.; Langmead, B.

10.1101/2021.03.23.436610 — bioinformatics — Posted on 2021-03-23

1362 The unraveling of balanced complexes in metabolic networks

Langary, D.; Kueken, A.; Nikoloski, Z.

10.1101/2021.03.23.436554 — bioinformatics — Posted on 2021-03-23

1363 Brain solute transport is more rapid in periarterial than perivenous spaces

Vinje, V.; Bakker, E. N. T. P.; Rognes, M. E.

10.1101/2021.03.23.436588 — bioengineering — Posted on 2021-03-23

1364 Evaluation and Optimization of High-Field Asymmetric Waveform Ion Mobility Spectrometry for Multiplexed Quantitative Site-specific N-glycoproteomics

Fang, P.; Ji, Y.; Silbern, I.; Viner, R.; Oellerich, T.; Pan, K.-T.; Urlaub, H.

10.1101/2021.03.23.436434 — biochemistry — Posted on 2021-03-23

1365 PRIMATE LIMB CONFORMATION: IMPLICATIONS FOR MECHANICAL ENERGY CONSERVATION

Catalino, M. P.

10.1101/2021.03.23.436575 — evolutionary biology — Posted on 2021-03-23

1366 Sexual selection affects the evolution of physiological and life history traits

Garlovsky, M. D.; Holman, L.; Brooks, A. L.; Snook, R. R.

10.1101/2021.03.23.436586 — evolutionary biology — Posted on 2021-03-23

1367 Immune stimulation alters chemical profiles of Tribolium castaneum

Lo, L. K.; R, R.; Tewes, L.-J.; Milutinovic, B.; Müller, C.; Kurtz, J.

10.1101/2021.03.23.436617 — evolutionary biology — Posted on 2021-03-23

1368 Linking habitat and population dynamics to inform conservation benchmarks for data-limited salmon stocks

Atlas, W. I.; Holt, C. A.; Selbie, D. T.; Connors, B. M.; Cox-Rogers, S.; Carr-Harris, C.; Hertz, E.; Moore, J. W.

10.1101/2021.03.22.436497 — ecology — Posted on 2021-03-23

1369 Salted roads lead to edema and reduced locomotor function in wood frogs

Frymus, L. E.; Goedert, D.; Zamora-Camacho, F. J.; Smith, P. C.; Zeiss, C. J.; Comas, M.; Abbott, T. A.; Basu, S. P.; DeAndressi, J. C.; Forgione, M. E.; Maloney, M. J.; Priester, J. L.; Senturk, F.; Szeligowski, R. V.; Tucker, A. S.; Zhang, M.; Calsbeek, R.; Brady, S. P.

10.1101/2021.03.23.436008 — ecology — Posted on 2021-03-23

1370 Shining a light on Laurentian Great Lakes cisco (Coregonus artedi): how ice coverage may impact embryonic development

Stewart, T. R.; Vinson, M. R.; Stockwell, J. D.

10.1101/2021.03.23.436622 — ecology — Posted on 2021-03-23

1371 Mycena species can be opportunist-generalist plant root invaders

Harder, C. B.; Hesling, E.; Botnen, S. S.; Dima, B.; von Bonsdorf-Salminen,, T. K.; Niskanen, T.; Jarvis, S.; Lorberau, K.; Ouimette, A. P.; Hester, A.; Hobbie, E. A.; Taylor, A.; Kauserud, H.

10.1101/2021.03.23.436563 — ecology — Posted on 2021-03-23

1372 Single cell transcriptome analysis of decidua macrophages in normal and recurrent spontaneous abortion patients

Zheng, Q.; Xu, X.; Yang, F.; Gan, H.; Zhao, Y.; Wan, X.; Jin, L.

10.1101/2021.03.23.436615 — cell biology — Posted on 2021-03-23

1373 The architecture of Cidec-mediated interfaces between lipid droplets

Ganeva, I.; Lim, K.; Boulanger, J.; Hoffmann, P. C.; Savage, D. B.; Kukulski, W.

10.1101/2021.03.23.436555 — cell biology — Posted on 2021-03-23

1374 Genome-wide decoupling of H2Aub and H3K27me3 in early mouse development

Zhu, Y.; Yu, J.; Rong, Y.; Wu, Y.-W.; Fan, H.-Y.; Shen, L.

10.1101/2021.03.23.436550 — molecular biology — Posted on 2021-03-23

1375 Serotonin and dopamine modulate aging in response to food perception and availability

Miller, H. A.; Huang, S.; Schaller, M. L.; Dean, E. S.; Tuckowski, A. M.; Munneke, A. S.; Beydoun, S.; Pletcher, S.; Leiser, S. F.

10.1101/2021.03.23.436516 — molecular biology — Posted on 2021-03-23

1376 A novel type of IRES having variable numbers of eIF4E-binding site and synergistic effect in RNA2 of WYMV isolates

Yuan, X.; Geng, G.; Yu, C.; Li, X.; Shi, K.

10.1101/2021.03.23.436552 — microbiology — Posted on 2021-03-23

1377 Should deep-sequenced amplicons become the new gold-standard for analysing malaria drug clinical trials?

Jones, S.; Kay, K.; Hodel, E. M.; Gruenberg, M.; Lerch, A.; Felger, I.; Hastings, I.

10.1101/2021.03.23.436602 — microbiology — Posted on 2021-03-23

1378 Aggregated Mycobacterium tuberculosis enhances the inflammatory response

Sigal, A.; Rodel, H.; Ferreira, I. M.; Ziegler, C.; Ganga, Y.; Bernstein, M.; Hwa, S.-H.; Kaplan, G.; Lustig, G.; Nargan, K.; Noursadeghi, M.; Steyn, A.; Shalek, A. K.

10.1101/2021.03.23.436577 — microbiology — Posted on 2021-03-23

1379 The oxygen sensor Prolyl hydroxylase domain 2 regulates the in vivo suppressive capacity of regulatory T cells

Ajouaou, Y.; Azouz, A.; Taquin, A.; Hussein, H.; Andris, F.; Moser, M.; Goriely, S.; Leo, O.

10.1101/2021.03.23.436597 — immunology — Posted on 2021-03-23

1380 Financial incentives facilitate the neural computation of prosocial decisions stronger in low empathic individuals

Iotzov, V.; Saulin, A.; Kaiser, J.; Han, S.; Hein, G.

10.1101/2021.03.23.436445 — neuroscience — Posted on 2021-03-23

1381 Temporal filtering of luminance and chromaticity in macaque visual cortex

Horwitz, G. D.

10.1101/2021.03.22.436512 — neuroscience — Posted on 2021-03-23

1382 Brain kernel: a new spatial covariance function for fMRI data

Wu, A.; Nastase, S. A.; Baldassano, C. A.; Turk-Browne, N. B.; Norman, K. A.; Engelhardt, B. E.; Pillow, J. W.

10.1101/2021.03.22.436524 — neuroscience — Posted on 2021-03-23

1383 Biophysical demonstration of co-packaging of glutamate and GABA in individual synaptic vesicles in the central nervous system

Kim, S.; Wallace, M.; El-Rifai, M.; Knudsen, A.; Sabatini, B.

10.1101/2021.03.23.436594 — neuroscience — Posted on 2021-03-23

1384 Sensitivity and resolution improvement for in-vivo magnetic resonance current density imaging (MRCDI) of the human brain

Goksu, C.; Scheffler, K.; Gregersen, F.; Eroglu, H. H.; Heule, R.; Siebner, H. R.; Hanson, L. G.; Thielscher, A.

10.1101/2021.03.23.436558 — neuroscience — Posted on 2021-03-23

1385 Reward boosts reinforcement-based motor learning

Vassiliadis, P.; Derosiere, G.; Dubuc, C.; Lete, A.; Crevecoeur, F.; Hummel, F. C.; Duque, J.

10.1101/2021.03.23.436627 — neuroscience — Posted on 2021-03-23

1386 Within- and transgenerational plasticity of a temperate salmonid in response to thermal acclimation and acute temperature stress

Penney, C. M.; Tabh, J. K. R.; Wilson, C. C.; Burness, G.

10.1101/2021.03.22.436503 — physiology — Posted on 2021-03-23

1387 PHAROH lncRNA regulates c-Myc translation in hepatocellular carcinoma via sequestering TIAR

Yu, A. T.; Berasain, C.; Bhatia, S.; Rivera, K.; Liu, B.; Rigo, F.; Pappin, D. J.; Spector, D. L.

10.1101/2021.03.23.436634 — cancer biology — Posted on 2021-03-23

1388 A Multiscale Immuno-Oncology on-Chip System (MIOCS) establishes that collective T cell behaviors govern tumor regression

Ronteix, G.; Jain, S.; Angely, C.; Cazaux, M.; Khazen, R.; Bousso, P.; Baroud, C.

10.1101/2021.03.23.435334 — biophysics — Posted on 2021-03-23

1389 On-off transition and ultrafast decay of amino acid luminescence driven by modulation of supramolecular packing

Arnon, Z. A.; Kreiser, T.; Yakimov, B.; Brown, N.; Aizen, R.; Shaham-Niv, S.; Makam, P.; Qaisrani, M. N.; Poli, E.; Ruggiero, A.; Slutsky, I.; Hassanali, A.; Shirshin, E.; Levy, D.; Gazit, E.

10.1101/2021.03.23.436384 — biophysics — Posted on 2021-03-23

1390 Physical mechanisms of ESCRT-III-driven cell division in archaea

Harker-Kirschneck, L.; Hafner, A. E.; Yao, T.; Pulschen, A. A.; Hurtig, F.; Vanhille Campos, C.; Hryniuk, D.; Culley, S.; Henriques, R.; Baum, B.; Saric, A.

10.1101/2021.03.23.436559 — biophysics — Posted on 2021-03-23

1391 VICTOR: A visual analytics web application for comparing cluster sets

Karatzas, E.; Gkonta, M.; Hotova, J.; Baltoumas, F. A.; Kontou, P. I.; Bobotsis, C. J.; Bagos, P. G.; Pavlopoulos, G. A.

10.1101/2021.03.22.436502 — bioinformatics — Posted on 2021-03-23

1392 Cell-to-cell and type-to-type heterogeneity of signaling networks: Insights from the crowd

Gabor, A.; Tognetti, M.; Driessen, A.; Tanevski, J.; Guo, B.; Cao, W.; Shen, H.; Yu, T.; Chung, V.; Single Cell Signaling in Breast Cancer DREAM Consortium, ; Bodenmiller, B.; Saez-Rodriguez, J.

10.1101/2021.03.23.436603 — bioinformatics — Posted on 2021-03-23

1393 Microbiome Maps: Hilbert Curve Visualizations of Metagenomic Profiles

Valdes, C.; Stebliankin, V.; Ruiz-Perez, D.; Park, J. I.; Lee, H.; Narasimhan, G.

10.1101/2021.03.22.436520 — bioinformatics — Posted on 2021-03-23

1394 Glycosaminoglycan content of a mineralized collagen scaffold promotes mesenchymal stem cell secretion of factors to modulate angiogenesis and monocyte differentiation

Dewey, M. J.; Kolliopoulos, V.; Ngo, M.; Harley, B.

10.1101/2021.03.23.436487 — bioengineering — Posted on 2021-03-23

1395 Insight into Lipopolysaccharide Translocation by Cryo-EM structures of a LptDE Transporter in Complex with Pro-Macrobodies

Botte, M.; Ni, D.; Schenck, S.; Zimmermann, I.; Chami, M.; Bocquet, N.; Egloff, P.; Bucher, D.; Trabuco, M.; Cheng, R. K. Y.; Brunner, J. D.; Seeger, M. A.; Stahlberg, H.; Hennig, M.

10.1101/2021.03.23.436624 — biochemistry — Posted on 2021-03-23

1396 A New Monocyte Epigenetic Clock Reveals Effects of Alcohol Consumption on Epigenetic Aging in Three Independent Cohorts

Liang, X.; Sinha, R.; Justice, A. C.; Cohen, M. H.; Aouizerat, B. E.; Xu, K.

10.1101/2021.03.22.436488 — genomics — Posted on 2021-03-23

1397 Functional variants in hematopoietic transcription factor footprints and their roles in the risk of immune system diseases

Kubota, N.; Suyama, M.

10.1101/2021.03.22.436360 — genomics — Posted on 2021-03-23

1398 Genes identified in rodent studies of alcohol intake are enriched for heritability of human substance use

Huggett, S. B.; Johnson, E. C.; Hatoum, A. S.; Lai, D.; Bubier, J. A.; Chesler, E. C.; Agrawal, A. A.; Palmer, A.; Edenberg, H. J.; Palmer, R. H. C.

10.1101/2021.03.22.436527 — genetics — Posted on 2021-03-23

1399 Dispersal across habitat boundaries: uncovering the demographic fates of populations in unsuitable habitat

Szojka, M. C.; Germain, R. M.

10.1101/2021.03.22.436493 — ecology — Posted on 2021-03-23

1400 Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair

Ide, S.; Kobayashi, Y.; Ide, K.; Strausser, S. A.; Herbek, S.; O'Brien, L. L.; Crowley, S. D.; Barisoni, L.; Tata, A.; Tata, P. R.; Souma, T.

10.1101/2021.03.23.436661 — cell biology — Posted on 2021-03-23

1401 Membrane insertion of Cavin1 facilitates caveolae assembly

Liu, K.-c.; Pace, H.; Larsson, E.; Hossain, S.; Kabedev, A.; Mohan, J.; Bergstrom, C. A. S.; Schwieger, C.; Hubert, M.; Lundmark, R.

10.1101/2021.03.23.436578 — cell biology — Posted on 2021-03-23

1402 Distinct domains of Me31B interact with different eIF4E isoforms in the male germ line of Drosophila melanogaster

Layana, C.; Vilardo, E. S.; Corujo, G.; Hernandez, G.; Rivera-Pomar, R.

10.1101/2021.03.23.436655 — molecular biology — Posted on 2021-03-23

1403 Dry Swab Method of sample collection for SARS-CoV2 testing can be used for culturing virus

Ram, S.; Enayathullah, M. G.; Parekh, Y.; Tallapaka, K. B.; Mishra, R. K.; Kiran Kumar, B.

10.1101/2021.03.23.436593 — microbiology — Posted on 2021-03-23

1404 V367F mutation in SARS-CoV-2 spike RBD emerging during the early transmission phase enhances viral infectivity through increased human ACE2 receptor binding affinity

Ou, J.; Zhou, Z.; Dai, R.; Zhao, S.; Wu, X.; Zhang, J.; Lan, W.; Cui, L.; Wu, J.; Seto, D.; Chodosh, J.; Zhang, G.; Zhang, Q.

10.1101/2020.03.15.991844 — microbiology — Posted on 2021-03-23

1405 Characterization and functional interrogation of SARS-CoV-2 RNA interactome

Labeau, A.; Lefevre-Utile, A.; Bonnet-Madin, L.; Fery-Simonian, L.; Soumelis, V.; Lotteau, V.; Vidalain, P.-O.; Amara, A.; Meertens, L.

10.1101/2021.03.23.436611 — microbiology — Posted on 2021-03-23

1406 The Dual-Antigen Ad5 COVID-19 Vaccine Delivered as an Intranasal Plus Subcutaneous Prime Elicits Th1 Dominant T-Cell and Humoral Responses in CD-1 Mice

Rice, A.; Verma, M.; Shin, A.; Zakin, L.; Sieling, P.; Tanaka, S.; Balint, J.; Dinkins, K.; Adisetiyo, H.; Morimoto, B.; Taft, J.; Patel, R. S.; Buta, S.; Martin-Fernandez, M.; Bogunovic, D.; Spilman, P. R.; Gabitzsch, E. R.; Safrit, J. T.; Rabizadeh, S.; Niazi, K.; Soon-Shiong, P.

10.1101/2021.03.22.436476 — immunology — Posted on 2021-03-23

1407 TCF-1 in CD8 T cells separates GVHD from GVL

Harris, R.; Mammadli, M.; May, A.; Yang, Q.; Fung, I. T. H.; Sen, J. M.; Karimi, M.

10.1101/2021.03.22.436494 — immunology — Posted on 2021-03-23

1408 Early life stress is associated with earlier emergence of permanent molars

McDermott, C. L.; Hilton, K.; Park, A. T.; Tooley, U. A.; Boroshok, A. L.; Mupparapu, M.; Scott, J. M.; Bumann, E. E.; Mackey, A. P.

10.1101/2021.03.22.436513 — neuroscience — Posted on 2021-03-23

1409 Adult neurogenesis mediates forgetting of multiple types of memory in the rat

Scott, G. A.; Terstege, D. J.; Roebuck, A. J.; Gorzo, K. A.; Vu, A. P.; Howland, J. G.; Epp, J. R.

10.1101/2021.03.22.436536 — neuroscience — Posted on 2021-03-23

1410 Symptomatic and Disease-Modifying Effects of GABAA Receptor Positive Allosteric Modulation in a Mouse Model of Chronic Stress

Bernardo, A.; Lee, P.; Marcotte, M.; Mian, Y.; Khan, Z. A.; Sharmin, D.; Cook, J. M.; Sibille, E.; Prevot, T. D.

10.1101/2021.03.22.436517 — neuroscience — Posted on 2021-03-23

1411 Inferring livestock movement networks from archived data to support infectious disease control in developing countries

Muwonge, A.; Bessel, P.; Porphyre, T.; Paolo, M.; Rydevik, G.; Devailly, G.; Franklyn, E. N.; Kelly, R. F.; Handel, I.; Mazeri, S.; Bronsvoort, B. M.

10.1101/2021.03.18.435930 — scientific communication and education — Posted on 2021-03-23

1412 The lifetime cost of reproductive potential, who spends the most?

Fuchs, S.; Goldenfeld, M.; Dviri, M.; Librach, C. L.; Baum, M.

10.1101/2021.03.22.432784 — physiology — Posted on 2021-03-23

1413 A Differential Equation for Mutation Rates in Environmental Coevolution.

Neal-Sturgess, C. E.

10.1101/2021.03.19.436176 — biophysics — Posted on 2021-03-23

1414 Off-resonance saturation as an MRI method to quantify ferritin-bound iron in the post-mortem brain

Bossoni, L.; Hegemann-Kleinn, I.; van Duinen, S. G.; Vroegindeweij, L. H. P.; Langendonk, J. G.; Hirschler, L.; Webb, A.; van der Weerd, L.

10.1101/2021.03.22.436424 — biophysics — Posted on 2021-03-23

1415 Deep neural network analysis employing diffusion basis spectrum imaging metrics as classifiers improves prostate cancer detection and grading

Ye, Z.; Yang, Q.; Lin, J.; Sun, P.; Shao, C.; Yu, Y.; Chen, L.; Zhu, Y.; Wu, A.; George, A.; Song, C.; Yang, R.; Zhan, J.; Gary, S.; Viox, J.; Wang, Z.; Wang, M.; Chen, Y.; Kim, E. H.; Ippolito, J.; Lu, J.; Song, S.-K.

10.1101/2021.03.22.436514 — bioinformatics — Posted on 2021-03-23

1416 scTenifoldKnk: a machine learning workflow performing virtual knockout experiments on single-cell gene regulatory networks

Osorio, D.; Zhong, Y.; Li, G.; Xu, Q.; Hillhouse, A. E.; Chen, J.; Davidson, L. A.; Tian, Y.; Chapkin, R. S.; Huang, J. Z.; Cai, J. J.

10.1101/2021.03.22.436484 — bioinformatics — Posted on 2021-03-23

1417 Population-scale detection of non-reference sequence variants using colored de Bruijn Graphs

Krannich, T.; White, W. T. J.; Niehus, S.; Holley, G.; Halldorsson, B.; Kehr, B.

10.1101/2021.03.23.436560 — bioinformatics — Posted on 2021-03-23

1418 HiCBin: Binning metagenomic contigs and recovering metagenome-assembled genomes using Hi-C contact maps

Du, Y.; Sun, F.

10.1101/2021.03.22.436521 — bioinformatics — Posted on 2021-03-23

1419 Optical and magnetic properties of particles containing guanine in strong basic solution

Iwasaka, M.

10.1101/2021.03.22.436526 — bioengineering — Posted on 2021-03-23

1420 Implementing QR Codes in Academia to Improve Sample Tracking, Data Accessibility, and Traceability in Multicampus Interdisciplinary Collaborations

Hernandez, C.; Aslankoohi, E.; Frolikov, P.; Kurniawan, S.; Rolandi, M.

10.1101/2021.03.22.436472 — bioengineering — Posted on 2021-03-23

1421 Encapsulation and recovery of murine hematopoietic stem and progenitor cells in a thiol-crosslinked maleimide-functionalized gelatin hydrogel

Gilchrist, A. E.; Serrano, J. F.; Ngo, M. T.; Hrnjak, Z.; Kim, S.; Harley, B.

10.1101/2021.03.22.436491 — bioengineering — Posted on 2021-03-23

1422 A non-invasive brain-machine interface via independent control of individual motor units

Formento, E.; Botros, P.; Carmena, J.

10.1101/2021.03.22.436518 — bioengineering — Posted on 2021-03-23

1423 Protein-primed RNA synthesis in SARS-CoVs and structural basis for inhibition by AT-527

Shannon, A.; Fattorini, V.; Sama, B.; Selisko, B.; Feracci, M.; Falcou, C.; Gauffre, P.; El Kazzi, P.; Decroly, E.; Rabah, N.; Toulon, K.; Eydoux, C.; Guillemot, J.-C.; Noel, M.; Debart, F.; Vasseur, J.-J.; Moussa, A.; Good, S.; Lin, K.; Sommadossi, J.-P.; Zhu, Y.; Yan, X.; Shi, H.; Ferron, F.; Canard, B.

10.1101/2021.03.23.436564 — biochemistry — Posted on 2021-03-23

1424 A novel approach to comparative RNA-Seq does not support a conserved set of genes underlying animal regeneration

Sierra, N.; Olsman, N.; Yi, L.; Pachter, L.; Goentoro, L.; Gold, D. A.

10.1101/2021.03.22.434850 — evolutionary biology — Posted on 2021-03-23

1425 Spatiotemporal variations of surface water microplastics near Kyushu, Japan: A quali-quantitative analysis

Kobayashi, T.; Yagi, M.; Kawaguchi, T.; Hata, T.; Shimizu, K.

10.1101/2021.03.22.436354 — ecology — Posted on 2021-03-23

1426 Influence of delayed density and ultraviolet radiation on caterpillar granulovirus infection and mortality

Pepi, A.; Pan, V.; Karban, R.

10.1101/2021.03.22.436482 — ecology — Posted on 2021-03-23

1427 Diverse arsenic-containing lipids in the surface ocean

Heal, K. R.; Maloney, A. E.; Ingalls, A. E.; Bundy, R. M.

10.1101/2021.03.22.436501 — ecology — Posted on 2021-03-23

1428 Genomic characterization of three novel Desulfobacterota classes expand the metabolic and phylogenetic diversity of the Phylum

Murphy, C. L.; Biggerstaff, J.; Eichhorn, A.; Ewing, E.; Shahan, R.; Soriano, D.; Stewart, S.; VanMol, K.; Walker, R.; Walters, P.; Elshahed, M. S.; Youssef, N. H.

10.1101/2021.03.22.436540 — microbiology — Posted on 2021-03-23

1429 Catalase Activity is Critical for Proteus mirabilis Biofilm Development, EPS Composition, and Dissemination During Catheter-Associated Urinary Tract Infection

White, A. N.; Learman, B. S.; Brauer, A. L.; Armbruster, C. E.

10.1101/2021.03.22.436542 — microbiology — Posted on 2021-03-23

1430 The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection

10.1101/2021.03.22.436522 — microbiology — Posted on 2021-03-23

1431 TCF-1 in CD4 T cells regulates GVHD severity and persistence

Harris, R.; Mammadli, M.; May, A.; Yang, Q.; Fung, I. T. H.; Sen, J. M.; Karimi, M.

10.1101/2021.03.22.436492 — immunology — Posted on 2021-03-23

1432 Passive clearing and 3D lightsheet imaging of the intact and injured spinal cord in mice

McCreedy, D. A.; Jalufka, F. L.; Platt, M. E.; Min, S. W.; Kirchhoff, M. A.; Manlapaz, R.; Mihaly, E.; Butts, J. C.; Iyer, N. R.; Sakiyama-Elbert, S. E.; Crone, S. A.; McDevitt, T. C.

10.1101/2021.03.22.434816 — neuroscience — Posted on 2021-03-23

1433 Failure of the brain glucagon-like peptide-1-mediated control of intestinal redox homeostasis in a rat model of sporadic Alzheimer's disease

Homolak, J.; Babic Perhoc, A.; Knezovic, A.; Osmanovic Barilar, J.; Salkovic-Petrisic, M.

10.1101/2021.03.22.436453 — neuroscience — Posted on 2021-03-23

1434 Noise Effect on the Temporal Patterns of Neural Synchrony

Zirkle, J.; Rubchinsky, L. L.

10.1101/2021.03.22.436529 — neuroscience — Posted on 2021-03-23

1435 Glucose-sensing in AgRP neurons integrates homeostatic energy state with dopamine signalling in the striatum.

Reichenbach, A.; Clarke, R.; Stark, R.; Lockie, S. H.; Mequinion, M.; Reed, F.; Rawlinson, S.; Dempsey, H.; Sepehrizadeh, T.; DeVeer, M.; Munder, A. C.; Nunez-Iglesias, J.; Spanswick, D. C.; Mynatt, R.; Kravitz, L.; Dayas, C. V.; Brown, R.; Andrews, Z. B.

10.1101/2021.03.22.436393 — neuroscience — Posted on 2021-03-23

1436 Antidepressant and antipsychotic drugs reduce viral infection by SARS-CoV-2 and fluoxetine show antiviral activity against the novel variants in vitro

Fred, M. S.; Kuivanen, S.; Ugurlu, H.; Cabrera Casarotto, P.; Levanov, L.; Saksela, K.; Vapalahti, O.; Castren, E.

10.1101/2021.03.22.436379 — pharmacology and toxicology — Posted on 2021-03-23

1437 Cancer models and statistical analysis of age distribution of cancers

Tetearing, A. N.

10.1101/2021.03.22.436464 — cancer biology — Posted on 2021-03-23

1438 Analysis of immune subtypes across the epithelial-mesenchymal plasticity spectrum

Chakraborty, P.; Chen, E.; McMullen, I.; Armstrong, A. J.; Jolly, M. K.; Somarelli, J. A.

10.1101/2021.03.22.436535 — cancer biology — Posted on 2021-03-23

1439 Label-free screening of brain tissue myelin content using phase imaging with computational specificity (PICS)

Fanous, M.; Shi, C.; Caputo, M.; Rund, L.; Johnson, R.; Das, T.; Kuchan, M.; Sobh, N.; Popescu, G.

10.1101/2021.03.22.436473 — bioinformatics — Posted on 2021-03-23

1440 Recognition of familiar objects in tortoise hatchlings (Testudo spp.)

Damini, S.; Stancher, G.; Versace, E.

10.1101/2021.03.22.436430 — animal behavior and cognition — Posted on 2021-03-23

1441 Optogenetic Activation of Striatal D1/D2 Medium Spiny Neurons Differentially Engages Downstream Connected Areas Beyond the Basal Ganglia

Grimm, C.; Frassle, S.; Steger, C.; von Ziegler, L.; Sturman, O.; Shemesh, N.; Bohacek, J.; Stephan, K. E.; Razansky, D.; Wenderoth, N.; Zerbi, V.

10.1101/2021.03.23.436576 — neuroscience — Posted on 2021-03-23

1442 Entangled radicals may explain lithium effects on hyperactivity

Zadeh-Haghighi, H.; Simon, C.

10.1101/2021.03.19.436086 — neuroscience — Posted on 2021-03-23

1443 A chromosome-level genome assembly of the European Beech (Fagus sylvatica) reveals anomalies for organelle DNA integration, repeat content and distribution of SNPs

Mishra, B.; Ulaszewski, B.; Meger, J.; Pfenninger, M.; Gupta, D. K.; Woetzel, S.; Ploch, S.; Burczyk, J.; Thines, M.

10.1101/2021.03.22.436437 — genomics — Posted on 2021-03-23

1444 Eusociality through conflict dissolution

Gonzalez-Forero, M.; Pena, J.

10.1101/2020.09.29.316877 — evolutionary biology — Posted on 2021-03-23

1445 Activity-mediated accumulation of potassium induces a switch in firing pattern and neuronal excitability type

Contreras Ceballos, S. A.; Schleimer, J.-H.; Gulledge, A. T.; Schreiber, S.

10.1101/2020.11.30.403782 — neuroscience — Posted on 2021-03-23

1446 The connectome spectrum as a canonical basis for a sparse representation of fast brain activity

Rue Queralt, J.; Glomb, K.; Pascucci, D.; Tourbier, S.; Carboni, M.; Vulliemoz, S.; Plomp, G.; Hagmann, P.

10.1101/2021.03.03.433561 — neuroscience — Posted on 2021-03-23

1447 Nicotine-mediated recruitment of GABAergic neurons to a dopaminergic phenotype attenuates motor deficits in alpha-synuclein Parkinson's model.

Lai, I.-C.; Romoli, B.; Keisler, M.; Manfredsson, F.; Powell, S. B.; Dulcis, D.

10.1101/2021.02.15.431290 — neuroscience — Posted on 2021-03-23

1448 Accurate and efficient time-domain classification with adaptive spiking recurrent neural networks

Yin, B.; Corradi, F.; Bohte, S. M.

10.1101/2021.03.22.436372 — neuroscience — Posted on 2021-03-23

1449 Autophagic degradation of the Cucumber mosaic virus virulence factor 2b balances antiviral RNA silencing with proviral plant fitness and virus seed transmission

Shukla, A.; Hoffmann, G.; Lopez-Gonzalez, S.; Hofius, D.; Hafren, A.

10.1101/2020.02.13.938316 — plant biology — Posted on 2021-03-23

1450 Pro-metastatic gene expression, immune evasion and an altered HPV spectrum characterize an aggressive subtype of cervical cancer

Chakravarthy, A.; Reddin, I.; Henderson, S.; Dong, C.; Kirkwood, N.; Jeyakumar, M.; McDermott, J.; Su, X.; Egawa, N.; Fjeldbo, C. S.; Halle, M. K.; Krakstad, C.; Soleiman, A.; Sprung, S.; Lyng, H.; Fiegl, H.; Salvesen, H.; Doorbar, J.; Chester, K.; Feber, A.; Fenton, T. R.

10.1101/2020.04.02.019711 — cancer biology — Posted on 2021-03-23

1451 VirStrain: a strain identification tool for RNA viruses

Liao, H.; Cai, D.; Sun, Y.

10.1101/2020.12.21.423722 — bioinformatics — Posted on 2021-03-23

1452 ORT: A workflow linking genome-scale metabolic models with reactive transport codes

Rubinstein, R. L.; Borton, M. A.; Zhou, H.; Shaffer, M.; Hoyt, D. W.; Stegen, J.; Henry, C. S.; Wrighton, K. C.; Versteeg, R.

10.1101/2021.03.02.433463 — bioinformatics — Posted on 2021-03-23

1453 Chimpanzees communicate to coordinate a cultural practice

Goldsborough, Z.; Schel, A. M.; J.C. van Leeuwen, E.

10.1101/2021.03.22.436386 — animal behavior and cognition — Posted on 2021-03-23

1454 Learning and motor-impulse control in crows and domestic chickens

Wascher, C. A. F.; Allen, K.; Szipl, G.

10.1101/2020.10.27.357764 — animal behavior and cognition — Posted on 2021-03-23

1455 Pax6 regulates the morphological and electrophysiological development of mouse prethalamic neurons

Tian, T.; Quintana-Urzainqui, I.; Kozic, Z.; Pratt, T.; Price, D. J.

10.1101/2021.03.22.436455 — developmental biology — Posted on 2021-03-23

1456 Gene expression profiling of malaria parasites reveals common virulence gene expression in adult first-time infected patients and severecases

Wichers, J. S.; Tonkin-Hill, G.; Thye, T.; Krumkamp, R.; Kreuels, B.; Strauss, J.; von Thien, H.; Scholz, J. A. M.; Smedegaard Hansson, H.; Jensen, R. W.; Turner, L.; Lorenz, F.-R.; Schoellhorn, A.; Bruchhaus, I.; Tannich, E.; Fendel, R.; Otto, T. D.; Lavstsen, T.; Gilberger, T. W.; Duffy, M. F.; Bachmann, A.

10.1101/2020.11.13.381137 — molecular biology — Posted on 2021-03-23

1457 Use and abuse of potential rates in soil microbiology

Hazard, C.; Prosser, J. I.; Nicol, G. W.

10.1101/2020.05.18.101253 — microbiology — Posted on 2021-03-23

1458 Heterologous vaccination regimens with self-amplifying RNA and Adenoviral COVID vaccines induce robust immune responses in mice

Spencer, A. J.; McKay, P. F.; Belij-Rammerstorfer, S.; Ulaszewska, M.; Bissett, C. D.; Hu, K.; Samnuan, K.; Blakney, A. K.; Sharpe, H. R.; Wright, D.; Gilbride, C.; Truby, A.; Allen, E. R.; Gilbert, S. C.; Shattock, R. J.; Lambe, T.

10.1101/2021.01.28.428665 — immunology — Posted on 2021-03-23

1459 Endosomal Acidification by NHE6-depletion Corrects ApoE4-mediated Synaptic Impairments and Reduces Amyloid Plaque Load

Pohlkamp, T.; Xian, X.; Durakoglugil, M. S.; Wong, C. H.; Evers, B. M.; White, C. L.; Connor, J.; Saido, T. C.; Hammer, R. E.; Herz, J.

10.1101/2021.03.22.436385 — neuroscience — Posted on 2021-03-23

1460 A Kalirin Missense Mutation Enhances Dendritic RhoA Signaling and Leads to Regression of Cortical Dendritic Arbors Across Development

Grubisha, M. J.; Sun, T.; Erickson, S. L.; Eisenman, L. R.; Chou, S.-y.; Helmer, C. D.; Trudgen, M. T.; Ding, Y.; Homanics, G. E.; Penzes, P.; Wills, Z. P.; Sweet, R.

10.1101/2021.03.22.436528 — neuroscience — Posted on 2021-03-23

1461 Distinct natural syllable-selective neuronal ensembles in the primary auditory cortex of awake marmosets

Zeng, h.; Huang, J.-f.; Shen, Z.; Gong, N.; Wen, Y.-q.; Wang, L.; Poo, M.-m.; Li, J.-r.

10.1101/2020.02.16.951194 — neuroscience — Posted on 2021-03-23

1462 EMC2: A versatile algorithm for robust tracking of calcium dynamics from individual neurons in behaving animals

Lagache, T.; Hanson, A.; Perez-Ortega, J. E.; Fairhall, A.; Yuste, R.

10.1101/2020.06.22.165696 — neuroscience — Posted on 2021-03-23

1463 An expanding manifold of transmodal regions characterizes adolescent reconfigurations of structural connectome organization

Park, B.-y.; Bethlehem, R. A. I.; Paquola, C.; Lariviere, S.; Cruces, R. R.; Vos de Wael, R.; Neuroscience in Psychiatry Network (NSPN) Consortium, ; Bullmore, E. T.; Bernhardt, B.

10.1101/2020.06.22.165621 — neuroscience — Posted on 2021-03-23

1464 The crystal structure of the Ca2+-ATPase 1 from Listeria monocytogenes reveals a pump primed for dephosphorylation

Basse Hansen, S.; Dyla, M.; Neumann, C. M. T.; Meldgaard Hogh Quistgaard, E.; Lauwring Andersen, J.; Kjaergaard, M.; Nissen, P.

10.1101/2020.06.23.166462 — biochemistry — Posted on 2021-03-23

1465 Non-Parametric Analysis of Inter-Individual Relations Using an Attention-Based Neural Network

Morita, T.; Toyoda, A.; Aisu, S.; Kaneko, A.; Suda-Hashimoto, N.; Adachi, I.; Matsuda, I.; Koda, H.

10.1101/2020.03.25.994764 — animal behavior and cognition — Posted on 2021-03-23

1466 Nestmate recognition of early brood in ants

de Fouchier, A.; Leroy, C.; Khila, A.; d'Ettorre, P.

10.1101/2021.03.17.435807 — animal behavior and cognition — Posted on 2021-03-23

1467 Evolution of mechanisms controlling epithelial morphogenesis across animals: new insights from dissociation - reaggregation experiments in the sponge Oscarella lobularis.

Vernale, A.; Prunster, M. M.; Marchiano, F.; Debost, H.; Brouilly, N.; Rocher, C.; Massey Harroche, D.; RENARD, E.; Le Bivic, A.; Habermann, B. H.; Borchiellini, C.

10.1101/2021.03.22.436370 — evolutionary biology — Posted on 2021-03-23

1468 Biophysical properties governing septin assembly

Woods, B. L.; Seim, I. L.; Liu, J.; McLaughlin, G.; Cannon, K. S.; Gladfelter, A. S.

10.1101/2021.03.22.436414 — cell biology — Posted on 2021-03-23

1469 Salty surfaces deter feeding in a blood-sucking disease vector

Pontes, G.; Latorre Estivalis, J. M.; Gutierrez, M. L.; Cano, A.; Beron de Astrada, M.; Lorenzo, M. G.; Barrozo, R. B.

10.1101/2021.03.22.436426 — physiology — Posted on 2021-03-23

1470 Chimpanzees communicate to coordinate a cultural practice

J.C. van Leeuwen, E.; Schel, A. M.; Golsborough, Z.

10.1101/2021.03.22.436386 — animal behavior and cognition — Posted on 2021-03-23

1471 A baton-relay mechanism for ER retrieval signal capture and proofreading by the KDEL receptor

Gerondopoulos, A.; Bräuer, P.; Sobajima, T.; Wu, Z.; Parker, J. L.; Biggin, P.; Barr, F. A.; Newstead, S.

10.1101/2021.03.21.436307 — cell biology — Posted on 2021-03-23

1472 Scaling dictates the decoder structure

Shen, J.; Liu, F.; Tang, C.

10.1101/2021.03.04.433820 — developmental biology — Posted on 2021-03-23

1473 Somewhere I Belong: Phylogenetic Comparative Methods and Machine Learning to Investigate the Evolution of a Species-Rich Lineage of Parasites

Cruz-Laufer, A. J.; Pariselle, A.; Jorissen, M. W. P.; Muterezi Bukinga, F.; Al Assadi, A.; Van Steenberge, M.; Koblmueller, S.; Sturmbauer, C.; Smeets, K.; Artois, T.; Vanhove, M. P. M.

10.1101/2021.03.22.435939 — evolutionary biology — Posted on 2021-03-23

1474 Analysis of motor unit spike trains estimated from high-density surface electromyography is highly reliable across operators

Hug, F.; Avrillon, S.; Del Vecchio, A.; Casolo, A.; Ibanez, J.; Nuccio, S.; Rossato, J.; Holobar, A.; Farina, D.

10.1101/2021.02.19.431376 — neuroscience — Posted on 2021-03-23

1475 Rubisco proton production can drive the elevation of CO2 within condensates and carboxysomes

Long, B. M.; Förster, B.; Pulsford, S. B.; Price, G. D.; Badger, M. R.

10.1101/2020.07.08.125609 — plant biology — Posted on 2021-03-23

1476 The plant circadian clock gene LHY influences Medicago truncatula nodulation

Achom, M.; Roy, P.; Lagunas, B.; Bonyadi-Pour, R.; Pardal, A.; Baxter, L. A.; Richmond, B.; Aschauer, N.; Fletcher, E.; Picot, E.; Rowson, M.; Blackwell, J.; Rich-Griffin, C.; Mysore, K. S.; Wen, J.; Ott, S.; Carre, I. A.; Gifford, M. L.

10.1101/2021.03.22.435813 — plant biology — Posted on 2021-03-23

1477 Structural basis for the hyperthermostability of an archaeal glutaminase induced by post-translational succinimide formation

Dongre, A. V.; Das, S.; Bellur, A.; Kumar, S.; Chandrashekarmath, A.; Karmakar, T.; Balaram, P.; Balasubramanian, S.; Balaram, H.

10.1101/2021.03.02.433506 — biochemistry — Posted on 2021-03-23

1478 Do exercise-associated genes explain phenotypic variance in the three components of fitness? A Systematic review & Meta-analysis.

Chung, H.; Roberts, J. D.; KEILLER, D. R.; Gordon, D. A.

10.1101/2021.03.22.436402 — physiology — Posted on 2021-03-22

1479 Allosteric communication in DNA polymerase clamp loaders relies on a critical hydrogen-bonded junction

Subramanian, S.; Gorday, K.; Marcus, K.; Orellana, M. R.; Ren, P.; Luo, X. R.; O'Donnell, M. E.; Kuriyan, J.

10.1101/2020.12.31.424921 — biophysics — Posted on 2021-03-23

1480 Skin aging risk factors: A nationwide population study in Mongolia

Nanzadsuren, T.; Myatav, T.; Dorjkhuu, A.; Ganbat, M.; Batbold, C.; Batsuuri, B.; Byamba, K.

10.1101/2021.03.22.436407 — evolutionary biology — Posted on 2021-03-22

1481 SNP- Based Assessment of Genetic Purity and Diversity in Maize Hybrid Breeding

Josia, C.; Mashingaidze, K.; Amelework, A. B.; Kondwakwenda, A.; Musvosvi, C.; Sibiya, J.

10.1101/2021.03.22.436406 — molecular biology — Posted on 2021-03-22

1482 Distribution, Epidemics dynamics and physiological races of wheat stem rust (Puccinia graminis f.sp. tritici Eriks and E. Henn) on irrigated wheat in the Awash River basin of Ethiopia

Yesuf, N. S.; Getahun, S.; Hassen, S.; Alemayehu, Y.; Danu, K. G.; Alemu, Z.; Tesfaye, T.; Hei, N. B.; Blasch, G.

10.1101/2021.03.22.436408 — molecular biology — Posted on 2021-03-22

1483 Grp78 alleviates sodium iodate-induced retinal cell injury in vivo and in vitro

liu, h.; jiang, s.; guo, y.; li, h.; yi, n.; hua liu,yongpeng guo,ning yi,hongdan li,

10.1101/2021.03.22.436404 — molecular biology — Posted on 2021-03-22

1484 The involvement of type IV pili and phytochrome in gliding motility, lateral motility and phototaxis of the cyanobacterium Phormidium lacuna

Lamparter, T.; Mielke, M.; Fröhlich, K.; Weber, N.; Wunsch, N.; Zaiss, F.; Schulz, K.; Spohrer, N.; Aschmann, V.; Krauss, N.; Babian, J.

10.1101/2021.03.22.436410 — microbiology — Posted on 2021-03-22

1485 The late endosome-resident lipid bis(monoacylglycero)phosphate is a cofactor for Lassa virus fusion

Markosyan, R. M.; Marin, M.; Zhang, Y.; Cohen, F. S.; Melikian, G.

10.1101/2021.03.22.436413 — microbiology — Posted on 2021-03-22

1486 Individualized Spatial Network Predictions Using Siamese Convolutional Neural Networks: A Resting-State fMRI Study of over 11,000 Unaffected Individuals

Hassanzadeh, R.; Silva, R. F.; Abrol, A.; Salman, M.; Bonkhoff, A.; Du, Y.; Fu, Z.; DeRamus, T.; Damaraju, E.; Baker, B.; Calhoun, V. D.

10.1101/2021.03.22.436403 — neuroscience — Posted on 2021-03-22

1487 Divergent epigenetic profiles from two differentially impacted wild populationsof estuarine cordgrass (Sporobolus alterniflorus)

DeCarlo, L.; Meckler, F.; Hans, M.; Kelemen, S.; Magun, H.; Noah, M.; Pappajohn, L.; Anderson, N.; Berger, R.; Berkel, J.; Brooke, N.; Chen, L.; Chijioke, O.; Dewees, N.; Faulkner, P.; Frank, J.; Holzman, W.; Marino, V.; Ravaschiere, A.; Wang, Y.; Williams, A.; Williams, Z.; Gentile, D.; Cox, R.

10.1101/2021.03.22.436412 — plant biology — Posted on 2021-03-22

1488 Recurrence quantification analysis of heart rate variability is a COVID-safe alternative to gas analysis in the detection of metabolic thresholds

Zimatore, G.; Falcioni, L.; Gallotta, M.; Bonavolnta, V.; Campanella, M.; De Spirito, M.; Guidetti, L.; Baldari, C.

10.1101/2021.03.22.436405 — biophysics — Posted on 2021-03-22

1489 Co3O4 /PAn Magnetic Nanoparticle-Modified Electrochemical Immunosensor for Azocyclotin

Wang, W.; Han, Z.; Xi, Q.; Gao, D.; Guo, R.; kuang, P.; Li, D.

10.1101/2021.03.22.436409 — biochemistry — Posted on 2021-03-22

1490 Cell surface hydrophobicity determines aggregate assembly type in Pseudomonas aeruginosa

Azimi, S.; Thomas, J.; Cleland, S.; Curtis, J. E.; Goldberg, J. B.; Diggle, S. P.

10.1101/2021.01.14.426723 — microbiology — Posted on 2021-03-22

1491 Facilitation of neural responses to targets moving against optic flow

Nicholas, S.; Nordstrom, K.

10.1101/2020.06.28.172536 — neuroscience — Posted on 2021-03-22

1492 Diffusional Kurtosis Imaging in the Diffusion Imaging in Python Project

Henriques, R. N.; Correia, M. M.; Maralle, M.; Huber, E.; Kruper, J.; Koudoro, S.; Yeatman, J. D.; Garyfallidis, E.; Rokem, A.

10.1101/2021.03.04.433972 — neuroscience — Posted on 2021-03-22

1493 Insula cortex gates the interplay of action observation and preparation for controlled imitation

Campbell, M. E. J.; Nguyen, V. T.; Cunnington, R.; Breakspear, M.

10.1101/2020.11.05.370718 — neuroscience — Posted on 2021-03-22

1494 Effects of green manure application on soil microbial communities and activities in the decontaminated sandy soil paddy field in Fukushima, Japan

Lee, C. G.; Mitsuda, Y.; Sugihara, S.; Ookawa, T.; Tanaka, H.

10.1101/2021.03.22.436377 — microbiology — Posted on 2021-03-22

1495 Targeting tau mitigates mitochondrial fragmentation and oxidative stress in amyotrophic lateral sclerosis

Petrozziello, T.; Bordt, E. A.; Mills, A. N.; Kim, S. E.; Sapp, E.; Devlin, B. A.; Obeng-Marnu, A. A.; Farhan, S. M. K.; Amaral, A. C.; Dujardin, S.; Dooley, P. M.; Henstridge, C.; Oakley, D. H.; Neueder, A.; Hyman, B. T.; Spires-Jones, T. L.; Bilbo, S. D.; Vakili, K.; Cudkowicz, M. E.; Berry, J. D.; DiFiglia, M.; Silva, M. C.; Haggarty, S. J.; Sadri-Vakili, G.

10.1101/2021.03.22.436505 — neuroscience — Posted on 2021-03-22

1496 BioViz Connect: Web application linking CyVerse science gateway resources to genomic visualization in the Integrated Genome Browser

Freese, N. H.; Raveendran, K.; Kintali, C.; Tiwari, S.; Bole, P.; Dias, C.; Loraine, A.

10.1101/2020.05.15.098533 — bioinformatics — Posted on 2021-03-22

1497 Isochoric supercooled preservation and revival of human cardiac microtissues

Powell-Palm, M. J.; Charwat, V.; Charrez, B.; Siemons, B. A.; Healy, K. E.; Rubinsky, B.

10.1101/2021.03.22.436466 — bioengineering — Posted on 2021-03-22

1498 Metazoans, migrations, and the ocean's biological carbon pump

Pinti, J.; DeVries, T.; Norin, T.; Serra-Pompei, C.; Proud, R.; Siegel, D. A.; Kiorboe, T.; Petrik, C. M.; Andersen, K. H.; Brierley, A. S.; Visser, A. W.

10.1101/2021.03.22.436489 — ecology — Posted on 2021-03-22

1499 Paraxial mesoderm organoids model development of human somites

Budjan, C.; Liu, S.; Ranga, A.; Gayen, S.; Pourquie, O.; Hormoz, S.

10.1101/2021.03.22.436471 — developmental biology — Posted on 2021-03-22

1500 Nutrient copper signaling promotes protein turnover by allosteric activation of ubiquitin E2D conjugases

Opazo, C. M.; Lotan, A.; Xiao, Z.; Zhang, B.; Greenough, M. A.; Lim, C. M.; Trytell, H.; Ramirez, A.; Ukuwela, A. A.; Mawal, C. H.; McKenna, J.; Saunders, D. N.; Burke, R.; Gooley, P. R.; Bush, A. I.

10.1101/2021.02.15.431211 — cell biology — Posted on 2021-03-22

1501 Proteome plasticity in response to persistent environmental change

Domnauer, M.; Zheng, F.; Li, L.; Zhang, Y.; Chang, C. E.; Unruh, J.; Conkright-Fincham, J.; McCroskey, S.; Florens, L.; Zhang, Y.; Seidel, C.; Fong, B.; Schilling, B.; Sharma, R.; Ramanathan, A.; Si, K.; Zhou, C.

10.1101/2021.03.22.436511 — molecular biology — Posted on 2021-03-22

1502 A toxic friend: Genotoxic and mutagenic activity of the probiotic strain Escherichia coli Nissle 1917

Nougayrede, J.-P.; Chagneau, C.; Motta, J.-P.; Bossuet-Greif, N.; Belloy, M.; Taieb, F.; Gratadoux, J.-J.; Thomas, M.; Langella, P.; Oswald, E.

10.1101/2021.03.22.436450 — microbiology — Posted on 2021-03-22

1503 Heightened virulence of Yersinia is associated with decreased function of the YopJ protein

Mares, C. A.; Lugo, F. P.; Albataineh, M.; Goins, B.; Newton, I.; Isberg, R. R.; Bergman, M.

10.1101/2021.03.22.436461 — microbiology — Posted on 2021-03-22

1504 Vibrio cholerae ParE2 toxin modulates its operon transcription by stabilization of an antitoxin DNA ruler

Garcia-Rodriguez, G.; Girardin, Y. A.; Singh, R. K.; Volkov, A. N.; Konijnenberg, A.; Sobott, F.; Charlier, D.; Loris, R.

10.1101/2021.03.22.436508 — microbiology — Posted on 2021-03-22

1505 Replicative fitness SARS-CoV-2 20I/501Y.V1 variant in a human reconstituted bronchial epithelium

Touret, F.; Luciani, L.; Baronti, C.; Cochin, M.; Driouich, J.-S.; Gilles, M.; Thirion, L.; Nougairede, A.; de Lamballerie, X.

10.1101/2021.03.22.436427 — microbiology — Posted on 2021-03-22

1506 The Card19 locus of murine chromosome 13 regulates terminal cell lysis downstream of caspase activation and Gasdermin-D cleavage

Bjanes, E.; Sillas, R. G.; Matsuda, R.; Demarco, B.; Fettrelet, T.; DeLaney, A. A.; Rodriguez Lopez, E. M.; Grubaugh, D.; Wynosky-Dolfi, M. A.; Philip, N. H.; Krespan, E.; Tovar, D.; Joannas, L.; Beiting, D. P.; Henao-Mejia, J.; Schaefer, B. C.; Chen, K. W.; Broz, P.; Brodsky, I. E.

10.1101/2021.03.19.436207 — immunology — Posted on 2021-03-22

1507 Emergence of directional bias in tau deposition from axonal transport dynamics

Torok, J.; Maia, P. D.; Verma, P.; Mezias, C.; Raj, A.

10.1101/2021.03.22.436470 — neuroscience — Posted on 2021-03-22

1508 Over-expression of the Regulator of the Signaling of G Protein-Coupled Receptors RGS9-2 reduces the signaling elicited by the human histamine H3 receptor in HEK-293T cells

Nieto-Alamilla, G.; Escamilla-Sanchez, J.; Arias-Montano, J. A.

10.1101/2021.03.22.435676 — neuroscience — Posted on 2021-03-22

1509 Cubam receptor-mediated endocytosis in hindgut-derived pseudoplacenta of a viviparous teleost Xenotoca eiseni

Iida, A.; Sano, K.; Inokuchi, M.; Nomura, J.; Suzuki, T.; Kuriki, M.; Sogabe, M.; Susaki, D.; Tonosaki, K.; Kinoshita, T.; Hondo, E.

10.1101/2021.02.01.429082 — zoology — Posted on 2021-03-22

1510 Generating complex patterns of gene expression without regulatory circuits

Shah, S. B.; Hill, A. M.; Wilke, C. O.; Hockenberry, A. J.

10.1101/2020.11.25.398248 — synthetic biology — Posted on 2021-03-22

1511 Genome-wide identification of the oat MLO family and identification of a candidate AsMLO associated with powdery mildew susceptibility

Reilly, A.; Gibriel, H. A. Y.; Karki, S. J.; Twamley, T.; Finnan, J.; Kildea, S.; Feechan, A.

10.1101/2021.03.22.435145 — plant biology — Posted on 2021-03-22

1512 A novel Wnt/beta-catenin signaling driven adipocyte population that is required for beiging

Liu, Z.; Chen, T.; Zhang, S.; Yang, T.; Gong, Y.; deng, H.-W.; Bai, D.; Tian, W.; Chen, Y.

10.1101/2021.01.14.426702 — physiology — Posted on 2021-03-22

1513 Placental uptake and metabolism as determinants of pregnancy vitamin D status

Ashley, B.; Simner, C.; Manousopoulou, A.; Jenkinson, C.; Hey, F.; Frost, J. M.; Rezwan, F. I.; White, C. H.; Lofthouse, E. M.; Hyde, E.; Cooke, L.; Barton, S.; Mahon, P.; Curtis, E. M.; Moon, R. J.; Crozier, S. R.; Inskip, H. M.; Godfrey, K. M.; Holloway, J. W.; Cooper, C.; Jones, K. S.; Lewis, R. M.; Hewison, M.; Garbis, S. D.; Branco, M. R.; Harvey, N. C.; Cleal, J. K.

10.1101/2021.03.01.431439 — physiology — Posted on 2021-03-22

1514 Contemporary clinical isolates of Staphylococcus aureus from pediatric osteomyelitis patients display unique characteristics in a mouse model of hematogenous osteomyelitis

Roper, P.; Eichelberger, K.; Cox, L.; O'Connor, L.; Shao, C.; Ford, C.; Fritz, S.; Cassat, J.; Veis, D.

10.1101/2021.03.22.436444 — pathology — Posted on 2021-03-22

1515 TWIST1 expression is associated with high-risk Neuroblastoma and promotes Primary and Metastatic Tumor Growth

Sepporta, M.-V.; Praz, V.; Balmas Bourloud, K.; Joseph, J.-M.; Jauquier, N.; Riggi, N.; Nardou-Auderset, K.; Petit, A.; Scoazec, J.-Y.; Sartelet, H.; Renella, R.; Muhlethaler-Mottet, A.

10.1101/2021.03.22.435811 — cancer biology — Posted on 2021-03-22

1516 Integration of Biodynamic Imaging and RNA-seq classifies chemotherapy response in canine diffuse large B-cell lymphoma

Fine, J.; Utturkar, S.; Dhawan, D.; Chopra, G.; Utturkar, S.; Turek, J.; Nolte, D.; Childress, M. O.; Lanman, N. A.

10.1101/2020.09.11.290353 — cancer biology — Posted on 2021-03-22

1517 Epigenomic tumor evolution modeling with single-cell methylation data profiling

Li, X. C.; Liu, Y.; Rashidi Mehrabadi, F.; Malikic, S.; Mount, S.; Ruppin, E.; Aldape, K.; Sahinalp, S. C.

10.1101/2021.03.22.436475 — cancer biology — Posted on 2021-03-22

1518 The cryo-EM structure of the bacterial type I DNA segregation ATPase filament reveals its conformational plasticity upon DNA binding.

Parker, A. V.; Mann, D.; Tzokov, S. B.; Hwang, L. C.; Bergeron, J. R.

10.1101/2021.03.22.436490 — biophysics — Posted on 2021-03-22

1519 Alternative dimerization is required for activity and inhibition of the HEPN ribonuclease RnlA

Garcia-Rodriguez, G.; Charlier, D.; Wilmaerts, D.; Michiels, J.; Loris, R.

10.1101/2021.03.22.436500 — biophysics — Posted on 2021-03-22

1520 Nanoscale Lubrication in Biosystems as Rationalized in Terms of Fractons and Spectral-Mechanical Properties of Networked Biopolymers in Ionic Solutions

Gadomski, A.; Beldowski, P.

10.1101/2021.03.22.436506 — biophysics — Posted on 2021-03-22

1521 Computational Structure Prediction Provides a Plausible Mechanism for Electron Transfer by the Outer Membrane Protein Cyc2 from Acidithiobacillus ferrooxidans

Jiang, V.; Khare, S. D.; Banta, S.

10.1101/2021.03.22.436458 — bioinformatics — Posted on 2021-03-22

1522 Protein-protein docking analysis reveals efficient binding and complex formation between the human nuclear transport proteins

Rathod, S. B.

10.1101/2021.03.22.436462 — bioinformatics — Posted on 2021-03-22

1523 A proteome-wide screen uncovers diverse roles for sequence context surrounding proline-rich motifs in Ena/VASP molecular recognition

Hwang, T.; Parker, S. S.; Hill, S. M.; Ilunga, M. W.; Grant, R. A.; Sivaraman, V.; Mouneimne, G.; Keating, A. E.

10.1101/2021.03.22.436451 — biochemistry — Posted on 2021-03-22

1524 Optogenetic manipulation of individual or whole population Caenorhabditis elegans worms with an under hundred-dollar tool: the OptoArm

Koopman, M.; Janssen, L.; Nollen, E.

10.1101/2021.03.19.435933 — genetics — Posted on 2021-03-22

1525 Predicting feral cat-reduction targets and costs on large islands using stochastic population models

Venning, K. R. W.; Saltre, F.; Bradshaw, C. J. A.

10.1101/2020.06.12.149393 — ecology — Posted on 2021-03-22

1526 RT-QuIC detection of CWD prion seeding activity in white-tailed deer muscle tissues

Li, M.; Schwabenlander, M. D.; Rowden, G. R.; Schefers, J. M.; Carstensen, M.; Seelig, D.; Larsen, P. A.

10.1101/2021.03.22.436515 — molecular biology — Posted on 2021-03-22

1527 Phylogenetic and population structure analyses uncover pervasive misclassification and help assessing the biosafety of Pseudomonas alloputida for biotechnological applications

Araujo, H. P.; Jacobs, S. H.; Franco, G. R.; Venancio, T. M.

10.1101/2020.12.22.423983 — microbiology — Posted on 2021-03-22

1528 First come, first served: Superinfection exclusion in Deformed wing virus is dependent upon sequence identity and not the order of virus acquisition.

Gusachenko, O.; Woodford, L.; Balbirnie-Cumming, K.; Evans, D. J.

10.1101/2021.03.22.436467 — microbiology — Posted on 2021-03-22

1529 Characterisation of B.1.1.7 and Pangolin coronavirus spike provides insights on the evolutionary trajectory of SARS-CoV-2

Dicken, S. J.; Murray, M. J.; Thorne, L. G.; Reuschl, A.-K.; Forrest, C.; Ganeshalingham, M.; Muir, L.; Kalemera, M. D.; Palor, M.; McCoy, L. E.; Jolly, C.; Towers, G. J.; Reeves, M.; Grove, J.

10.1101/2021.03.22.436468 — microbiology — Posted on 2021-03-22

1530 The multi-functional reovirus σ3 protein is a virulence factor that suppresses stress granule formation to allow viral replication and myocardial injury

Guo, Y.; Hinchman, M. M.; Lewandrowski, M.; Cross, S. T.; Sutherland, D. M.; Welsh, O. L.; Dermody, T. S.; Parker, J. S. L.

10.1101/2021.03.22.436456 — microbiology — Posted on 2021-03-22

1531 Plasmodium falciparum serology: A comparison of two protein production methods for analysis of antibody responses by protein microarray

Oulton, T.; Obiero, J.; Rodriguez, I.; Ssewanyana, I.; Dabbs, R. A.; Greenhouse, B.; Drakeley, C.; Felgner, P. L.; Stone, W.; Tetteh, K. K.

10.1101/2020.12.15.422854 — immunology — Posted on 2021-03-22

1532 Differential effects of the second SARS-CoV-2 mRNA vaccine dose on T cell immunity in naive and COVID-19 recovered individuals

Camara, C.; Lozano-Ojalvo, D.; Lopez-Granados, E.; Paz-Artal, E.; Pion, M.; Correa-Rocha, R.; Ortiz, A.; Lopez-Hoyos, M.; Erro Iribarren, M.; Portoles, J.; Portoles, P.; Perez-Olmeda, M.; Oteo-Iglesias, J.; Berin, C.; Guccione, E.; Bertoletti, A.; Ochando, J.

10.1101/2021.03.22.436441 — immunology — Posted on 2021-03-22

1533 The ENIGMA Toolbox: Cross-disorder integration and multiscale neural contextualization of multisite neuroimaging datasets

Lariviere, S.; Paquola, C.; Park, B.-y.; Royer, J.; Wang, Y.; Benkarim, O.; Vos de Wael, R.; Valk, S. L.; Thomopoulos, S. I.; Kirschner, M.; ENIGMA Consortium, ; Lewis, L. B.; Evans, A. C.; Sisodiya, S.; McDonald, C.; Thompson, P. M.; Bernhardt, B.

10.1101/2020.12.21.423838 — neuroscience — Posted on 2021-03-22

1534 Temporal Window based Feature Extraction Technique for Motor-Imagery EEG Signal Classification

Banerjee, S.; Chatterjee, R.; Chatterjee, A.; Sanyal, D. K.

10.1101/2021.03.19.436144 — neuroscience — Posted on 2021-03-22

1535 Neural heterogeneity promotes robust learning

Perez-Nieves, N.; Leung, V. C. H.; Dragotti, P. L.; Goodman, D. F. M.

10.1101/2020.12.18.423468 — neuroscience — Posted on 2021-03-22

1536 Numerical Uncertainty in Analytical Pipelines Lead to Impactful Variability in Brain Networks

Kiar, G.; Chatelain, Y.; de Oliveira Castro, P.; Petit, E.; Rokem, A.; Varoquaux, G.; Misic, B.; Evans, A. C.; Glatard, T.

10.1101/2020.10.15.341495 — neuroscience — Posted on 2021-03-22

1537 Neurexin and Frizzled signaling intercept axonal-transport at microtubule minus-ends to control synapse formation

Balseiro-Gomez, S.; Yue, Y.; Shao, L.; Cetinkaya, S.; Kuzoian, C.; Verhey, K. J.; Yogev, S.

10.1101/2021.03.22.436477 — neuroscience — Posted on 2021-03-22

1538 Complete loss of CASK causes severe ataxia through cerebellar degeneration in human and mouse

Patel, P.; Hegert, J.; Cristian, I.; Kerr, A.; LaConte, L.; Fox, M.; Srivastava, S.; Mukherjee, K.

10.1101/2021.03.22.436280 — neuroscience — Posted on 2021-03-22

1539 Predicting genotype-specific gene regulatory networks

Weighill, D. A.; Ben Guebila, M.; Glass, K.; Quackenbush, J.; Platig, J.

10.1101/2021.01.18.427134 — systems biology — Posted on 2021-03-22

1540 A Humanized Antibody against LRG1 that Inhibits Angiogenesis and Reduces Retinal Vascular Leakage

Kallenberg, D.; Tripathi, V.; Javaid, F.; Pilotti, C.; George, J.; Davis, S.; Blackburn, J. W.; O'Connor, M.; Dowsett, L.; Bowers, C.; Liyanage, S. E.; Gourlaouen, M.; Hoeh, A.; Mota, F.; Selwood, D.; Bainbridge, J.; Tufail, A.; Chudasama, V.; Greenwood, J.; Moss, S. E.

10.1101/2020.07.25.218149 — pathology — Posted on 2021-03-22

1541 Fast ATP-dependent subunit rotation in reconstituted FoF1-ATP synthase trapped in solution

Heitkamp, T.; Börsch, M.

10.1101/2021.03.21.436299 — biophysics — Posted on 2021-03-22

1542 Quickomics: exploring omics data in an intuitive, interactive and informative manner

Gao, B.; Zhu, J.; Negi, S.; Zhang, X.; Gyoneva, S.; Casey, F.; Wei, R.; Zhang, B.

10.1101/2021.01.19.427296 — bioinformatics — Posted on 2021-03-22

1543 Engineering the Immune Adaptor Protein STING as a Biologic

Sun, X.; Ni, Y.; He, Y.; Yang, M.; Tani, T.; Kitajima, S.; Barbie, D. A.; Li, J.

10.1101/2021.02.18.431824 — bioengineering — Posted on 2021-03-22

1544 Genome-wide association study and polygenic risk score analysis for hearing measures in children

Schmitz, J.; Abbondanza, F.; Paracchini, S.

10.1101/2020.07.22.215376 — genetics — Posted on 2021-03-22

1545 Gliding in the Amazonian canopy: adaptive evolution of flight in Morpho butterflies

Le Roy, C.; Amadori, D.; Charberet, S.; Windt, J.; Muijres, F. T.; Llaurens, V.; Debat, V.

10.1101/2021.03.22.436469 — evolutionary biology — Posted on 2021-03-22

1546 Joint language production: an electrophysiological investigation of simulated lexical access on behalf of task partner

Kuhlen, A. K.; Abdel Rahman, R.

10.1101/2020.09.18.303099 — neuroscience — Posted on 2021-03-22

1547 Mental Chronometry of Speaking in Dialogue: Semantic Interference Turns into Facilitation

Kuhlen, A. K.; Abdel Rahman, R.

10.1101/2020.09.08.287458 — neuroscience — Posted on 2021-03-22

1548 Schizophrenia-linked protein tSNARE1 regulates endolysosomal trafficking in cortical neurons

Plooster, M.; Farrell, M. S.; Rossi, G.; Won, H.; Gupton, S. L.; Brennwald, P. J.

10.1101/2021.02.09.430442 — neuroscience — Posted on 2021-03-22

1549 Thyroid Hormone Dependent Transcriptional Programming by TRβ Requires SWI/SNF Chromatin Remodelers

Gillis, N. E.; Boyd, J. R.; Tomczak, J. A.; Frietze, S.; Carr, F. E.

10.1101/2021.03.22.436429 — genomics — Posted on 2021-03-22

1550 Pseudomonas aeruginosa reaches collective decisions via transient segregation of quorum sensing activities across cells

Jayakumar, P.; Thomas, S. A.; Brown, S. P.; Kuemmerli, R.

10.1101/2021.03.22.436499 — microbiology — Posted on 2021-03-22

1551 SMARCA4 regulates spatially restricted metabolic plasticity in 3D multicellular tissue

Cermakova, K.; Smith, E. A.; Chan, Y. S.; Loeza Cabrera, M.; Chambers, C.; Jarvis, M.; Simon, L. M.; Xu, Y.; Jain, A.; Putluri, N.; Chen, R.; Ripley, R. T.; Veiseh, O.; Hodges, H. C.

10.1101/2021.03.21.436346 — systems biology — Posted on 2021-03-22

1552 Brain Iron Imaging Markers in the Presence of White Matter Hyperintensities

Murray, K. D.; Uddin, M. N.; Schifitto, G.; Uddin, M. N.; Zhong, J.

10.1101/2021.03.22.436449 — pathology — Posted on 2021-03-22

1553 Machine learning approaches to identify core and dispensable genes in pangenomes

Yocca, A. E.; Edger, P. P.

10.1101/2021.03.22.436446 — bioinformatics — Posted on 2021-03-22

1554 TMPRSS2 inhibitor discovery facilitated through an in silico and biochemical screening platform

Peiffer, A. L.; Garlick, J. M.; Wu, Y.; Soellner, M. B.; Brooks, C. L.; Mapp, A. K.

10.1101/2021.03.22.436465 — biochemistry — Posted on 2021-03-22

1555 A chromosome-level genome assembly of the European Beech (Fagus sylvativa) reveals anomalies for organelle DNA integration, repeat content and distribution of SNPs

Mishra, B.; Ulaszewski, B.; Meger, J.; Pfenninger, M.; Gupta, D. K.; Woetzel, S.; Ploch, S.; Burczyk, J.; Thines, M.

10.1101/2021.03.22.436437 — genomics — Posted on 2021-03-22

1556 Drosophila primary microRNA-8 encodes a microRNA encoded peptide (miPEP) acting in parallel of miR-8

Montigny, A.; Tavormina, P.; Duboe, C.; San Clemente, H.; Aguilar, M.; Valenti, P.; Lauressergues, D.; Combier, J. P.; Plaza, S.

10.1101/2021.03.22.434418 — developmental biology — Posted on 2021-03-22

1557 Structural modeling of the SARS-CoV-2 Spike/human ACE2 complex interface can identify high-affinity variants associated with increased transmissibility

Gan, H. H.; Twaddle, A.; Marchand, B.; Gunsalus, K.

10.1101/2021.03.22.436454 — molecular biology — Posted on 2021-03-22

1558 Increased ACTL6A Occupancy Within mSWI/SNF Chromatin Remodelers Drives Human Squamous Cell Carcinoma

Chang, C.-Y.; Shipony, Z.; Kuo, A.; Loh, K. M.; Greenleaf, W. J.; Crabtree, G. R.

10.1101/2021.03.22.435873 — molecular biology — Posted on 2021-03-22

1559 Live imaging of SARS-CoV-2 infection in mice reveals neutralizing antibodies require Fc function for optimal efficacy

Ullah, I.; Prevost, J.; Ladinsky, M. S.; Stone, H.; Lu, M.; Anand, S. P.; Beaudoin-Bussieres, G.; Benlarbi, M.; Ding, S.; Gasser, R.; Fink, C.; Chen, Y.; Tauzin, A.; Goyette, G.; Bourassa, C.; Medjahed, H.; Mack, M.; Chung, K.; Wilen, C. B.; Dekaban, G. A.; Dikeakos, J. D.; Bruce, E. A.; Kaufmann, D. E.; Stamatatos, L.; McGuire, A.; Richard, J.; Pazgier, M.; Bjorkman, P.; Mothes, W.; Finzi, A.; Kumar, P.; Uchil, P. D.

10.1101/2021.03.22.436337 — immunology — Posted on 2021-03-22

Cowan, E. T.; Fain, M. R.; O'Shea, I.; Ellman, L. M.; Murty, V. P.

10.1101/2021.03.22.436448 — neuroscience — Posted on 2021-03-22

1561 New insights into the allosteric effects of CO2 and bicarbonate on crocodilian hemoglobin

Bautista, N. M.; Malte, H.; Natarajan, C.; Wang, T.; Storz, J. F.; Fago, A.

10.1101/2021.03.22.436447 — physiology — Posted on 2021-03-22

1562 Predicting hosts based on early SARS-CoV-2 samples and analyzing later world-wide pandemic in 2020

Guo, Q.; Li, M.; Wang, C.; Guo, J.; Jiang, X.; Tan, J.; Wu, S.; Wang, P.; Xiao, T.; Zhou, M.; Fang, Z.; Xiao, Y.; Zhu, H.

10.1101/2021.03.21.436312 — bioinformatics — Posted on 2021-03-22

1563 Two-stage Linked Component Analysis for Joint Decomposition of Multiple Biologically Related Data Sets

Chen, H.; Caffo, B.; Stein-O'Brien, G.; Liu, J.; Langmead, B.; Colantuoni, C.; Xiao, L.

10.1101/2021.03.22.435728 — bioinformatics — Posted on 2021-03-22

1564 HolistiC: Leveraging Hi-C and Whole Genome Shotgun Sequencing for Double Minute Chromosome Discovery

Hayes, M.; Nguyen, A.; Islam, R.; Butler, C.; Tran, E.; Mullins, D.; Hicks, C.

10.1101/2021.03.22.435038 — bioinformatics — Posted on 2021-03-22

1565 Benchtop Carbon Fiber Microelectrode Array Fabrication Toolkit

Richie, J. M.; Patel, P. R.; Welle, E. J.; Dong, T.; Chen, L.; Shih, A. J.; Chestek, C. A.

10.1101/2021.03.22.436422 — bioengineering — Posted on 2021-03-22

1566 Principles of RNA recruitment to viral ribonucleoprotein condensates in a segmented dsRNA virus

Strauss, S.; Borodavka, A.; Papa, G.; Desiro, D.; Schueder, F.; Jungmann, R.

10.1101/2021.03.22.435476 — biochemistry — Posted on 2021-03-22

1567 Origin of diversity in spatial social dilemmas

Hauert, C.; Doebeli, M.

10.1101/2021.03.21.436334 — evolutionary biology — Posted on 2021-03-22

1568 Developmental timing scales wing patterning between avian species

Towers, M.; Stainton, H.

10.1101/2021.03.22.436457 — developmental biology — Posted on 2021-03-22

1569 An mRNA vaccine against SARS-CoV-2: Lyophilized, liposome-based vaccine candidate EG-COVID induces high levels of virus neutralizing antibodies

Kim, S.-H.; Cho, Y. J.; Hong, H. C.; Kim, K. S.; Park, S. A.; Chun, M. J.; Hong, E. Y.; Chung, S. W.; Kim, H. J.; Shin, B. G.

10.1101/2021.03.22.436375 — molecular biology — Posted on 2021-03-22

1570 High rates of plasmid cotransformation in E. coli overturn the clonality myth and reveal colony development

Tomoiaga, D.; Bubnell, J. E.; Herndon, L.; Feinstein, P.

10.1101/2021.03.19.434223 — molecular biology — Posted on 2021-03-22

1571 CVnCoV protects human ACE2 transgenic mice from ancestral B BavPat1 and emerging B.1.351 SARS-CoV-2

Hoffmann, D.; Corleis, B.; Rauch, S.; Roth, N.; Muehe, J.; Halwe, N. J.; Ulrich, L.; Fricke, C.; Schoen, J.; Kraft, A.; Breithaupt, A.; Wernike, K.; Michelitsch, A.; Sick, F.; Wylezich, C.; Mueller, S. O.; Mettenleiter, T. C.; Petsch, B.; Dorhoi, A.; Beer, M.

10.1101/2021.03.22.435960 — microbiology — Posted on 2021-03-22

1572 Protease-activatable biosensors of SARS-CoV-2 infection for cell-based drug, neutralisation and virological assays

Pereyra Gerber, P.; Duncan, L. M.; Greenwood, E. J.; Marelli, S.; Naamati, A.; Teixeira-Silva, A.; Crozier, T. W.; Gabaev, I.; Zhan, J. R.; Protasio, A. V.; Matheson, N. J.

10.1101/2021.03.22.435957 — microbiology — Posted on 2021-03-22

1573 Revealing Notch-dependencies in synaptic targets associated with Alzheimer's disease

Perna, A.; Marathe, S.; Dreos, R.; Akarsu, H.; Falquet, L.; Alberi, L.

10.1101/2021.03.22.436438 — neuroscience — Posted on 2021-03-22

1574 Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment

Zhou, Y.; Xu, J.; Hou, Y.; Leverenz, J. B.; Kallianpur, A.; Mehra, R.; Liu, Y.; Yu, H.; Pieper, A. A.; Jehi, L.; Cheng, F.

10.1101/2021.03.15.435423 — systems biology — Posted on 2021-03-22

1575 A fast and efficient smoothing approach to Lasso regression and an application in statistical genetics: polygenic risk scores for chronic obstructive pulmonary disease (COPD)

Hahn, G.; Lutz, S. M.; Laha, N.; Cho, M. H.; Silverman, E. K.; Lange, C.

10.1101/2020.03.06.980953 — bioinformatics — Posted on 2021-03-22

1576 Combined computational and cellular screening identifies synergistic inhibition of SARS-CoV-2 by lenvatinib and remdesivir

Pohl, M. O.; Busnadiego, I.; Marrafino, F.; Wiedmer, L.; Hunziker, A.; Fernbach, S.; Omori, E.; Hale, B. G.; Caflisch, A.; Stertz, S.

10.1101/2021.03.19.435806 — microbiology — Posted on 2021-03-22

1577 Immune characterization and profiles of SARS-CoV-2 infected patients reveals potential host therapeutic targets and SARS-CoV-2 oncogenesis mechanism

Policard, M.; Jain, S.; Rego, S.; Dakshanamurthy, S.

10.1101/2021.02.17.431721 — immunology — Posted on 2021-03-22

1578 Structural Analysis of Spike Protein Mutations in the SARS-CoV-2 P.3 Variant

Bascos, N. A. D.; Mirano-Bascos, D.; Saloma, C. P.

10.1101/2021.03.06.434059 — biophysics — Posted on 2021-03-22

1579 An autoregulation loop in fust-1 for circular RNA regulation in Caenorhabditis elegans

Cao, D.

10.1101/2021.03.22.436400 — genetics — Posted on 2021-03-22

1580 Evolution and spread of SARS-CoV-2 likely to be affected by climate

Bajaj, P.; Arya, P. C.

10.1101/2020.06.18.147074 — evolutionary biology — Posted on 2021-03-22

1581 LPS core type diversity in the Escherichia coli species and associations with phylogeny and virulence gene repertoire.

Leclercq, S. O.; Branger, M.; Smith, D. G.; GERMON, P.

10.1101/2021.03.22.436425 — microbiology — Posted on 2021-03-22

1582 New Records of California Serogroup Virus in Aedes Mosquitoes and First Detection in Simulioidae Flies from Northern Canada and Alaska

Villeneuve, C.-A.; Buhler, K. J.; Iranpour, M.; Avard, E.; Dibernardo, A.; Fenton, H.; Dibernardo, C.; Gouin, G. G.; Loseto, L.; Jenkins, E.; Lindsay, L. R.; Dusfour, I.; Leighton, P. A.; Lecomte, N.

10.1101/2021.03.22.433603 — microbiology — Posted on 2021-03-22

1583 Refinement of corticospinal neuron activity during skilled motor learning

Serradj, N.; Marino, F.; Moreno-Lopez, Y.; Agger, S.; Sloan, A. M.; Hollis, E. R.

10.1101/2021.03.22.436415 — neuroscience — Posted on 2021-03-22

1584 Comparative performance analysis of mulberry silkworm (Bombyx mori L.) races for integration of superior yield and maximize profit in West Bengal

Kaviraj, M.; Kumar, U.; Chatterjee, S.; Swain, S.; Singh, M.; Nandi, K.

10.1101/2021.03.22.436391 — zoology — Posted on 2021-03-22

1585 Population diversity of cassava mosaic begomoviruses increases over the course of serial vegetative propagation

Aimone, C. D.; Lavington, E.; Hoyer, J. S.; Deppong, D. O.; Mickelson-Young, L.; Jacobson, A.; Kennedy, G. G.; Carbone, I.; Hanley-Bowdoin, L.; Duffy, S.

10.1101/2021.03.22.436436 — plant biology — Posted on 2021-03-22

1586 Personalized Virus Load Curves of SARS-CoV-2 Infection

Hillen, T.; Contreras, C.; Newby, J.

10.1101/2021.01.21.427676 — physiology — Posted on 2021-03-22

1587 Antiviral Resistance against Viral Mutation: Praxis and Policy for SARS CoV-2

Penner, R. C.

10.1101/2021.02.25.432861 — bioinformatics — Posted on 2021-03-22

1588 The role of DDK and Treslin-MTBP in coordinating replication licensing and pre-Initiation Complex formation

Volpi, I.; Gillespie, P. J.; Chadha, G. S.; Blow, J.

10.1101/2021.03.22.436442 — biochemistry — Posted on 2021-03-22

1589 Introduction bias: Imbalance in species introductions may obscure the identification of traits associated with invasiveness

Palma, E.; Yen, J.; Vesk, P.; Vila, M.; Catford, J.

10.1101/2021.03.22.436397 — ecology — Posted on 2021-03-22

1590 Slippery when wet: cross-species transmission of divergent coronaviruses in bony and jawless fish and the evolutionary history of the Coronaviridae

Miller, A. K.; Mifsud, J. C. O.; Costa, V. A.; Grimwood, R. M.; Kitson, J.; Baker, C.; Brosnahan, C. L.; Pande, A.; Holmes, E. C.; Gemmell, N.; Geoghegan, J. L.

10.1101/2021.03.22.436364 — microbiology — Posted on 2021-03-22

1591 Polycomb repressive complex 2 coordinates with Sin3 histone deacetylase complex to epigenetically reprogram genome-wide expression of effectors and regulate pathogenicity in Magnaporthe oryzae

Wu, Z.; Qiu, J.; Shi, H.; Lin, C.; Yue, J.; Liu, Z.; Xie, W.; Kou, Y.; Tao, z.

10.1101/2021.03.21.436344 — microbiology — Posted on 2021-03-22

1592 Rapidly self-sterilizing PPE capable of 99.9% SARS-CoV-2 deactivation in 30 seconds

Zinn, A. A.; Izadjoo, M.; Kim, H.; Kehn-Hall, K.; Lehman, C.; Brody, R. L.; Roth, R. R.; Vega, A.; Nguyen, K. K.; Ngo, N. T.; Zinn, H. T.; Panny, L.; Flor, R.; Antonopoulos, N.; Stoltenberg, R. M.

10.1101/2020.11.16.384040 — immunology — Posted on 2021-03-22

1593 Genome-wide screen identifies curli amyloid fibril as a bacterial component promoting host neurodegeneration

WANG, C.; Lau, C. Y.; Ma, F.; Zheng, C.

10.1101/2021.03.22.436366 — neuroscience — Posted on 2021-03-22

1594 Single cell chromatin accessibility reveals regulatory elements and developmental trajectories in the embryonic forebrain

Rhodes, C. T.; Mitra, A.; Lee, D. R.; Lee, D. J.; Zhang, Y.; Thompson, J. J.; Rocha, P. P.; Dale, R. K.; Petros, T. J.

10.1101/2021.03.21.436353 — neuroscience — Posted on 2021-03-22

1595 Microglial refinement of spinal cord sensory circuitry regulates normal maturation of dynamic touch.

Xu, Y.; Koch, S.; Chamessian, A.; He, Q.; Sundukova, M.; Heppenstall, P.; Ji, R. R.; Fitzgerald, M.; Beggs, S.

10.1101/2021.03.22.436389 — neuroscience — Posted on 2021-03-22

1596 Accurate and efficient time-domain classification with adaptive spiking recurrent neural networks

Yin, B.; Bohte, S. M.

10.1101/2021.03.22.436372 — neuroscience — Posted on 2021-03-22

1597 Cold Adaptation Leads To Repolarization Gradients Development In The Rainbow Trout Heart

Vaykshnorayte, M. A.; Vityazev, V. A.; Azarov, J.

10.1101/2021.03.22.436433 — physiology — Posted on 2021-03-22

1598 A synthetic tubular molecular transport system

Stommer, P.; Kiefer, H.; Kopperger, E.; Honemann, M. N.; Kube, M.; Simmel, F. C.; Netz, R. R.; Dietz, H.

10.1101/2021.03.22.436416 — biophysics — Posted on 2021-03-22

1599 Identifying Differential Methylation in Cancer Epigenetics via a Bayesian Functional Regression Model

Shokoohi, F.; Stephens, D. A.; Greenwood, C. M.

10.1101/2021.03.21.436232 — bioinformatics — Posted on 2021-03-22

1600 Make Interactive Complex Heatmaps in R

Gu, Z.; Huebschmann, D.

10.1101/2021.03.08.434289 — bioinformatics — Posted on 2021-03-22

1601 Molecular insights into the μ-opioid receptorselective signaling

Sounier, R.; Granier, S.; Maurel, D.; Cong, X.; DEMENE, H.; Saint-Paul, J.; Peysson, F.; Vasiliauskaite-Brooks, I.; Hagelberger, J.; Golebiowski, J.

10.1101/2021.03.22.436421 — bioinformatics — Posted on 2021-03-22

1602 The Central Importance of Hub Proteins in a Disease-Gene Network Model: A New Paradigm of Chronic Myeloid Leukemia Disease Study

Rahman, K. M. T.; Islam, M. F.; Saha, S.; Billah, M. M.

10.1101/2021.03.21.436331 — bioinformatics — Posted on 2021-03-22

1603 A highly accurate model for screening prostate cancer using propensity index panel of ten genes

Jain, S.; Malhotra, K. P. K.; Patiyal, S.; Raghava, G. P. S.

10.1101/2021.03.22.436371 — bioinformatics — Posted on 2021-03-22

1604 A novel method for generating 3D constructs with branched vascular networks using multi-materials bioprinting and direct surgical anastomosis

Liu, X.; Wang, X.; Zhang, L.; Sun, L.; Wang, H.; Zhao, H.; Zhang, Z.; Huang, Y.; Zhang, J.; Song, B.; Li, C.; Zhang, H.; Li, S.; Wang, S.; Zheng, X.; Gu, Q.

10.1101/2021.03.21.436268 — bioengineering — Posted on 2021-03-22

1605 Turning movements in real life capture subtle longitudinal and preataxic changes in cerebellar ataxia

Thierfelder, A.; Seemann, J.; John, N.; Giese, M. A.; Schoels, L.; Timmann, D.; Synofzik, M.; Ilg, W.

10.1101/2021.03.22.436330 — bioengineering — Posted on 2021-03-22

1606 A method for intuitively extracting macromolecular dynamics from structural disorder

Pearce, N. M.; Gros, P.

10.1101/2021.03.22.436387 — biochemistry — Posted on 2021-03-22

1607 From temporal network data to the dynamics of social relationships

Gelardi, V.; Barrat, A.; Claidiere, N.

10.1101/2021.03.22.436267 — animal behavior and cognition — Posted on 2021-03-22

1608 Functional variants in hematopoietic transcription factor footprints and their roles in the risk of immune system diseases

Kubota, N.; Suyama, M.

10.1101/2021.03.22.436360 — genomics — Posted on 2021-03-22

1609 Disease-specific eQTL screening reveals an anti-fibrotic effect of AGXT2 in nonalcoholic fatty liver disease

Yoo, T.; Joo, S. K.; Kim, H. J.; Kim, H. Y.; Sim, H.; Lee, J.; Kim, H.-H.; Jung, S.; Lee, Y.; Jamialahmadi, O.; Romeo, S.; Jeong, W.-I.; Hwang, G.-S.; Kang, K. W.; Kim, J. W.; Kim, W.; Choi, M.

10.1101/2021.03.22.436368 — genetics — Posted on 2021-03-22

1610 Mutations in a β-group of solute carrier gene are responsible for egg and eye coloration of the brown egg 4 (b-4) mutant in the silkworm, Bombyx mori

Tomihara, K.; Satta, K.; Matsuzaki, S.; Yoshitake, K.; Yamamoto, K.; Uchiyama, H.; Yajima, S.; Futahashi, R.; Katsuma, S.; Osanai-Futahashi, M.; Kiuchi, T.

10.1101/2021.03.22.436376 — genetics — Posted on 2021-03-22

1611 Functional diversity alters the effects of a pulse perturbation on the dynamics of tritrophic food webs

Ceulemans, R.; Wojcik, L. A. M.; Gaedke, U.

10.1101/2021.03.22.436420 — ecology — Posted on 2021-03-22

1612 Dependence of an aquatic insect population on contemporaneous primary production

Phillips, J. S.; McCormick, A. R.; Botsch, J. C.; Ives, A. R.

10.1101/2021.03.22.436388 — ecology — Posted on 2021-03-22

1613 A beta-glucosidase of an insect herbivore determines both toxicity and deterrence of a dandelion defense metabolite

Huber, M.; Roder, T.; Irmisch, S.; Riedel, A.; Gablenz, S.; Fricke, J.; Rahfeld, P.; Reichelt, M.; Paetz, C.; Liechti, N.; Hu, L.; Meng, Y.; Huang, W.; Robert, C. A.; Gershenzon, J.; Erb, M.

10.1101/2021.03.22.436380 — ecology — Posted on 2021-03-22

1614 α1-COP delivers sphingolipid modifiers and controls plasmodesmal callose deposition in Arabidopsis

Iswanto, A. B. B.; Vu, M. H.; Kumar, R.; Shon, J. C.; Wu, S.; Kim, D.-R.; Sik, K. Y.; Hui, S. G.; Kang, H.; Kim, W. Y.; Kim, S. H.; Liu, K. H.; Kim, J.-Y.

10.1101/2021.03.22.436362 — cell biology — Posted on 2021-03-22

1615 SAF-A promotes origin licensing and replication fork progression to ensure robust DNA replication

Connolly, C.; Takahashi, S.; Miura, H.; Hiratani, I.; Gilbert, N.; Donaldson, A. D.; Hiraga, S.-i.

10.1101/2021.03.22.436394 — cell biology — Posted on 2021-03-22

1616 Integrative genome-scale metabolic modeling reveals versatile metabolic strategies for methane utilization in Methylomicrobium album BG8

Villada, J. C.; Duran, M. F.; Lim, C. K.; Stein, L. Y.; Lee, P. K. H.

10.1101/2021.03.21.436352 — microbiology — Posted on 2021-03-22

1617 Post-transcriptional regulation of Leishmania fitness gain

Piel, L.; Rajan, K. S.; Bussotti, G.; Varet, H.; Legendre, R.; Proux, C.; Douche, T.; Giai Gianetto, Q.; Chaze, T.; Vojtkova, B.; Gordon-Bar, N.; Doniger, T.; Cohen-Chalamish, S.; Rengaraj, P.; Besse, C.; Boland, A.; Sadlova, J.; Deleuze, J.-F.; Matondo, M.; Unger, R.; Volf, P.; Michaeli, S.; Pescher, P.; Spaeth, G. F.

10.1101/2021.03.22.436378 — microbiology — Posted on 2021-03-22

1618 Neural networks and extreme gradient boosting predict multiple thresholds and trajectories of microbial biodiversity responses due to browning

Fontaine, L.; Khomich, M.; Andersen, T.; Hessen, D. O.; Rasconi, S.; Davey, M. L.; Eiler, A.

10.1101/2021.03.22.435765 — microbiology — Posted on 2021-03-22

1619 Plasmodium falciparum serology: A comparison of two protein production methods for analysis of antibody responses by protein microarray

Oulton, T.; Obiero, J.; Rodriguez, I.; Ssewanyana, I.; Dabbs, R. A.; Greenhouse, B.; Drakeley, C.; Felgner, P. L.; Stone, W.; Tetteh, K. K.

10.1101/2020.12.15.422854 — immunology — Posted on 2021-03-22

1620 Application of high dimensional flow cytometry and unsupervised analysis to define the immune cell landscape of early childhood respiratory and blood compartments

Shanthikumar, S.; Ranganathan, S. C.; Saffery, R.; Neeland, M. R.

10.1101/2021.03.21.436363 — immunology — Posted on 2021-03-22

1621 Effect of aqueous extract of Antiaris africana stem bark on phagocytic activities of human neutrophils ex-vivo.

Bello, I. O.; Adedeji, L. A.

10.1101/2021.03.21.436291 — immunology — Posted on 2021-03-22

1622 Prenatal cadmium exposure does not induce greater incidence or earlier onset of autoimmunity in the offspring

McCall, J. L.; Blair, H. C.; Blethen, K.; Hall, C.; Elliott, M.; Barnett, J. B.

10.1101/2021.03.22.436398 — immunology — Posted on 2021-03-22

1623 Opponent vesicular transporters regulate the strength of glutamatergic neurotransmission in a C. elegans sensory circuit

Choi, J.-H.; Horowitz, L. B.; Ringstad, N.

10.1101/2021.03.20.436253 — neuroscience — Posted on 2021-03-22

1624 Temporal Window based Feature Extraction Technique for Motor-Imagery EEG Signal Classification

Banerjee, S.; Chatterjee, R.

10.1101/2021.03.19.436144 — neuroscience — Posted on 2021-03-22

1625 Why humans are stronger but not faster after isometric strength training: specific neural, not muscular, motor unit adaptations

Del Vecchio, A.; Casolo, A.; Dideriksen, J.; Aagaard, P.; Felici, F.; Falla, D.; Farina, D.

10.1101/2021.03.20.436242 — neuroscience — Posted on 2021-03-22

1626 Meta-learning local synaptic plasticity for continual familiarity detection

Tyulmankov, D.; Yang, G. R.; Abbott, L.

10.1101/2021.03.21.436287 — neuroscience — Posted on 2021-03-22

1627 Mechanosensory input shapes Drosophila motor behavior through Patterned Spontaneous Network Activity

Carreira-Rosario, A.; York, R. A.; Choi, M.; Doe, C. Q.; Clandinin, T. R.

10.1101/2021.03.21.436277 — neuroscience — Posted on 2021-03-22

1628 Respiration, heartbeat, and conscious tactile perception

Grund, M.; Al, E.; Pabst, M.; Dabbagh, A.; Stephani, T.; Nierhaus, T.; Villringer, A.

10.1101/2021.03.22.436396 — neuroscience — Posted on 2021-03-22

1629 Single dose of amphetamine induces delayed subregional attenuation of striatal cholinergic interneuron activity

Ztaou, S.; Oh, S. J.; Tepler, S.; Fleury, S.; Matamales, M.; Bertran-Gonzalez, J.; Chuhma, N.; Rayport, S.

10.1101/2021.03.22.436417 — neuroscience — Posted on 2021-03-22

1630 Explicit and implicit depth-cue integration: evidence of systematic biases with real objects

Campagnoli, C.; Hung, B.; Domini, F.

10.1101/2021.03.19.436171 — neuroscience — Posted on 2021-03-22

1631 Sex-specific life extension in tauopathy mice by CSF1R inhibition causing selective microglial depletion and suppressed pathogenesis

Johnson, N. R.; Yuan, P.; Lopez, T. P.; Yue, W.; Bond, A.; Rivera, B. M.; Hirouchi, M.; Giles, K.; Aoyagi, A.; Condello, C.

10.1101/2021.03.20.436288 — neuroscience — Posted on 2021-03-22

1632 Replicative senescence dictates the emergence of disease-associated microglia and contributes to Abeta pathology

Hu, Y.; Fryatt, G. L.; Ghorbani, M.; Obst, J.; Menassa, D. A.; Martin-Estebane, M.; Muntslag, T. A. O.; Olmos-Alonso, A.; Guerrero-Carrasco, M.; Thomas, D. L.; Cragg, M. S.; Gomez-Nicola, D.

10.1101/2021.03.22.436174 — neuroscience — Posted on 2021-03-22

1633 Modulation of pulsatile GnRH dynamics across the ovarian cycle: the role of excitability within the arcuate kisspeptin network

Voliotis, M.; Li, X. F.; De Burgh, R.; Lass, G.; Ivanova, D.; McIntyre, C.; O'Byrne, K. T.; Tsaneva-Atanasova, K.

10.1101/2021.03.22.436428 — neuroscience — Posted on 2021-03-22

1634 Motion extrapolation in the flash-lag effect depends on perceived, rather than physical speed

Yook, J.; Lee, L.; Vossel, S.; Weidner, R.; Hogendoorn, H.

10.1101/2021.03.22.436374 — neuroscience — Posted on 2021-03-22

1635 Protein allocation and utilization in the versatile chemolithoautotroph Cupriavidus necator

Jahn, M.; Crang, N.; Janasch, M.; Hober, A.; Forsström, B.; Kimler, K.; Mattausch, A.; Chen, Q.; Asplund-Samuelsson, J.; Hudson, E. P.

10.1101/2021.03.21.436304 — systems biology — Posted on 2021-03-22

1636 A Class of Simple Biomolecular Antithetic Proportional-Integral-Derivative Controllers

Filo, M. G.; Khammash, M.

10.1101/2021.03.21.436342 — synthetic biology — Posted on 2021-03-22

1637 Endosperm turgor pressure both promotes and restricts seed growth and size

Creff, A.; Ali, O.; Bayle, V.; Ingram, G.; Landrein, B.

10.1101/2021.03.22.436392 — plant biology — Posted on 2021-03-22

1638 A metabolomics insight into the Cyclic Nucleotide Monophosphate signaling cascade in tomato under non-stress and salinity conditions

Miras-Moreno, B.; Zhang, L.; Senizza, B.; Lucini, L.

10.1101/2021.03.22.436432 — plant biology — Posted on 2021-03-22

1639 Coupling between protrusion dynamics and polarized trafficking steers persistent cell migration

Vaidziulyte, K.; Mace, A.-S.; Battistella, A.; Beng, W.; Schauer, K.; Coppey, M.

10.1101/2021.03.20.436273 — biophysics — Posted on 2021-03-22

1640 Fast ATP-dependent subunit rotation in reconstituted FoF1-ATP synthase trapped in solution

Heitkamp, T.; Börsch, M.

10.1101/2021.03.21.436299 — biophysics — Posted on 2021-03-22

1641 Information-Efficient, Off-Center Sampling Results in Improved Precision in 3D Single Particle Tracking Microscopy

Welsher, K.; Zhang, C.

10.1101/2021.03.21.436327 — biophysics — Posted on 2021-03-22

1642 MultiGWAS: An integrative tool for Genome Wide Association Studies (GWAS) in tetraploid organisms

Garreta, L. E.; Ceron-Souza, I.; Palacio, M. R.; Reyes, P.

10.1101/2020.08.16.252791 — bioinformatics — Posted on 2021-03-22

1643 CopyMix: Mixture Model Based Single-Cell Clustering and Copy Number Profiling using Variational Inference

Safinianaini, N.; P. E. de Souza, C.; Lagergren, J.

10.1101/2020.01.29.926022 — bioinformatics — Posted on 2021-03-22

1644 MAAPER: model-based analysis of alternative polyadenylation using 3' end-linked reads

Li, W. V.; Zheng, D.; Wang, R.; Tian, B.

10.1101/2021.03.21.436343 — bioinformatics — Posted on 2021-03-22

1645 Identification of regulatory networks associated with anti-HIV/AIDS genes via integrated transcriptome, epigenome and proteome analyses

Liu, G.; Zhang, C.; Shi, L.; Zhu, Z.

10.1101/2021.03.21.436300 — bioinformatics — Posted on 2021-03-22

1646 Song complexity in relation to repertoire size and phonological syntax in the breeding song of Purple Sunbird

Chorol, S.; Jain, M.

10.1101/2021.03.20.436261 — animal behavior and cognition — Posted on 2021-03-22

1647 Avoiding attack: How dune wasps leverage colour and motion to detect their cryptic spider predators

Rodriguez-Morales, D.; Tapia-McClung, H.; Robledo Ospina, L. E.; Rao, D.

10.1101/2021.03.20.436281 — animal behavior and cognition — Posted on 2021-03-22

1648 Somewhere I Belong: Phylogenetic Comparative Methods and Machine Learning to Investigate the Evolution of a Species-Rich Lineage of Parasites

Cruz-Laufer, A. J.; Pariselle, A.; Jorissen, M. W. P.; Muterezi Bukinga, F.; Al Assadi, A.; Van Steenberge, M.; Koblmueller, S.; Sturmbauer, C.; Smeets, K.; Artois, T.; Vanhove, M. P. M.

10.1101/2021.03.22.435939 — evolutionary biology — Posted on 2021-03-22

1649 Genomic architecture and evolutionary dynamics of a social niche polymorphism in the California harvester ant, Pogonomyrmex californicus

Errbii, M.; Ernst, U. R.; Lajmi, A.; Gadau, J.; Schrader, L.

10.1101/2021.03.21.436260 — evolutionary biology — Posted on 2021-03-22

1650 Minimal clustering and species delimitation based on multi-locus alignments vs SNPs: the case of the Seriphium plumosum L. complex (Gnaphalieae: Asteraceae)

Shaik, Z.; Bergh, N. G.; Oxelman, B.; Verboom, A. G.

10.1101/2021.03.21.436318 — evolutionary biology — Posted on 2021-03-22

1651 Lower Vibrio spp. abundances in Zostera marina leaf canopies suggest a novel ecosystem function for temperate seagrass beds

Reusch, T. B. H.; Schubert, P. R.; Marten, S.-M.; Gill, D.; Karez, R.; Busch, K.; Hentschel, U.

10.1101/2021.03.21.436319 — ecology — Posted on 2021-03-22

1652 Stochasticity-induced stabilization weakens in diverse communities.

Pande, J.; Shnerb, N.

10.1101/2021.03.21.436309 — ecology — Posted on 2021-03-22

1653 piRNA pathway is essential for generating functional oocytes in golden hamster

Zhang, H.; Zhang, F.; Chen, J.; Li, M.; Lv, X.; Xiao, Y.; Zhang, Z.; Hou, L.; Lai, Y.; Xiao, W.; Zhang, A.; Fu, H.; Zhou, J.; Diao, F.; Shi, A.; Su, Y.; Zeng, W.; Wu, L.; Li, J.

10.1101/2021.03.21.434510 — developmental biology — Posted on 2021-03-22

1654 Computational modeling of C-terminal tails to predict the calcium-dependent secretion of ER resident proteins

Trychta, K. A.; Xie, B.; Verma, R.; Xu, M.; Shi, L.; Harvey, B. K.

10.1101/2021.03.21.435734 — cell biology — Posted on 2021-03-22

1655 Rabaptin5 targets autophagy to damaged early endosomes and Salmonella containing vacuoles by interaction with FIP200 and ATG16L1

Millarte, V.; Schlienger, S.; Kälin, S.; Spiess, M.

10.1101/2020.09.01.277764 — cell biology — Posted on 2021-03-22

1656 Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin

Wang, J. S.; Kamath, T.; Mirzamohammadi, F.; Rotter, D.; Hojo, H.; Castro, C. D.; Patel, R.; Govea, N.; Enishi, T.; Wu, Y.; Martins, J. d. S.; Bruce, M.; Brooks, D. J.; Bouxsein, M. L.; Tokarz, D.; Lin, C. P.; Abdul, A.; Macosko, E. Z.; Fiscaletti, M.; Munns, C. F.; Fujiwara, M.; Kronenberg, H. M.; Wein, M. N.

10.1101/2021.03.22.436056 — molecular biology — Posted on 2021-03-22

1657 Identification of biomarkers and candidate regulators for multiple myeloma under the knockout of AURKA

Gu, H.; Wang, W.; Yuan, G.

10.1101/2021.03.21.436324 — immunology — Posted on 2021-03-22

1658 Evolution of MEG: a first MEG-feasible fluxgate magnetometer

Koshev, N.; Butorina, A.; Skidchenko, E.; Kuzmichev, A.; Ossadtchi, A.; Ostras, M.; Fedorov, M.; Vetoshko, P.

10.1101/2021.03.22.435762 — neuroscience — Posted on 2021-03-22

1659 Gambling on an empty stomach: Hunger modulates preferences for learned but not described risks

van Swieten, M. M. H.; Bogacz, R.; Manohar, S. G.

10.1101/2021.03.19.435837 — neuroscience — Posted on 2021-03-22

1660 Automated long-term two-photon imaging in head-fixed walking Drosophila

Flores Valle, A.; Honnef, R.; Seelig, J. D.

10.1101/2021.03.20.436241 — neuroscience — Posted on 2021-03-22

1661 The impact of brain lesions on tDCS-induced electric field magnitude

Johnstone, A.; Zich, C.; Evans, C.; Lee, J.; Ward, N. S.; Bestmann, S.

10.1101/2021.03.19.436124 — neuroscience — Posted on 2021-03-22

1662 Top-down acetylcholine contributes to social discrimination via enabling action potentials in olfactory bulb vasopressin cells

Suyama, H.; Egger, V.; Lukas, M.

10.1101/2020.11.09.373845 — neuroscience — Posted on 2021-03-22

1663 Convergence of clinically relevant manipulations on dopamine-regulated prefrontal activity underlying stress-coping responses

Wilke, S. A.; Lavi, K.; Byeon, S.; Sohal, V. S.

10.1101/2021.03.20.436282 — neuroscience — Posted on 2021-03-22

1664 Structural Covariance Networks in Post-Traumatic Stress Disorder: A Multisite ENIGMA-PGC Study

Rakesh, G.; Sun, D.; Logue, M.; Clarke-Rubright, E.; O'Leary, B. M.; Haswell, C.; Xie, H.; Thompson, P.; Dennis, E.; Jahanshad, N.; Koch, S.; Frijling, J.; Nawijn, L.; Olff, M.; van Zuiden, M.; Rashid, F.; Zhu, X.; De Bellis, M.; Daniels, J. K.; Sierk, A.; Manthey, A.; Stevens, J. S.; Jovanovic, T.; Stein, M. B.; Shenton, M.; van der Werff, S. J. A.; van der Wee, N. J. A.; Vermeiren, R. R. J. M.; Schmahl, C.; Herzog, J.; Kaufman, M. L.; O'Connor, L.; Lebois, L. A. M.; Baker, J. T.; Gruber, S. A.; Wolff, J. D.; Wolf, E. J.; Winternitz, S.; Gonenc, A.; Ressler, K. J.; Hofmann, D.; Bryant, R. A.;

10.1101/2021.03.13.432212 — neuroscience — Posted on 2021-03-22

1665 Neural Representation of the Relational Self from Infancy to Adulthood

Ulmer Yaniv, A.; Waidergoren, S.; Shaked, A.; Salomon, R.; Feldman, R.

10.1101/2021.03.21.436295 — neuroscience — Posted on 2021-03-22

1666 Hippocampal sharp wave-ripples and the associated sequence replay emerge from structured synaptic interactions in a network model of area CA3

Ecker, A.; Bagi, B.; Vertes, E.; Steinbach-Nemeth, O.; Karlocai, M. R.; Papp, O. I.; Miklos, I.; Hajos, N.; Freund, T. F.; Gulyas, A. I.; Kali, S.

10.1101/2021.02.18.431868 — neuroscience — Posted on 2021-03-22

1667 Molecular features of RNA silencing against phloem-restricted polerovirus TuYV enable amplification of silencing signal from host transcripts

Clavel, M.; Lechner, E.; Incarbone, M.; Vincent, T.; Cognat, V.; Smirnova, E.; Lecorbeiller, M.; Brault, V.; Ziegler-Graff, V.; Genschik, P.

10.1101/2021.03.19.436175 — plant biology — Posted on 2021-03-22

1668 Unilateral corneal insult in Zebrafish results in a bilateral cell shape and identity modification, supporting wound closure

Ikkala, K.; Stratoulias, V.; Michon, F.

10.1101/2021.03.21.436164 — physiology — Posted on 2021-03-22

1669 Dihydropyrimidinase-like 2 (DPYSL2) regulates breast cancer migration via a JAK/STAT3/vimentin axis

Abu Rmaileh, A.; Solaimuthu, B.; Ben Yosef, M.; Khatib, A.; Lichtenstein, M.; Tanna, M.; Hayashi, A.; Pillar, N.; Shaul, Y. D.

10.1101/2021.03.21.436294 — cancer biology — Posted on 2021-03-22

1670 SPART, a versatile and standardized data exchange format for species partition information

Miralles, A.; Ducasse, J.; Brouillet, S.; Flouri, T.; Fujisawa, T.; Kapli, P.; Knowles, L. L.; Kumari, S.; Stamatakis, A.; Sukumaran, J.; Lutteropp, S.; Vences, M.; Puillandre, N.

10.1101/2021.03.22.435428 — bioinformatics — Posted on 2021-03-22

1671 Population-specific genome graphs improve high-throughput sequencing data analysis: A case study on the Pan-African genome

Tetikol, H. S.; Narci, K.; Turgut, D.; Budak, G.; Kalay, O.; Arslan, E.; Demirkaya-Budak, S.; Dolgoborodov, A.; Jain, A.; Kabakci-Zorlu, D.; Brown, R.; Semenyuk, V.; Davis-Dusenbery, B.

10.1101/2021.03.19.436173 — bioinformatics — Posted on 2021-03-22

1672 Accel-Align: A Fast Sequence Mapper and Aligner based on the Seed-Embed-Extend Method

Yan, Y.; Chaturvedi, N.; Appuswamy, R.

10.1101/2020.07.20.211888 — bioinformatics — Posted on 2021-03-22

1673 Optical Nanosensors for Real-time Feedback on Insulin Secretion by β-Cells

Ehrlich, R.; Hendler-Neumark, A.; Wulf, V.; Amir, D.; Bisker, G.

10.1101/2021.03.21.435763 — bioengineering — Posted on 2021-03-22

1674 Naked mole-rats (Heterocephalus glaber) do not specialise on cooperative tasks

Siegmann, S.; Feitsch, R.; Hart, D. W.; Bennett, N. C.; Penn, D. J.; Zoettl, M.

10.1101/2021.03.22.436002 — animal behavior and cognition — Posted on 2021-03-22

1675 The effects of experimental floral resource removal on plant-pollinator interactions

Bain, J. A.; Dickson, R. G.; Gruver, A. M.; CaraDonna, P. J.

10.1101/2021.03.21.436328 — ecology — Posted on 2021-03-22

1676 dCas9 targeted chromatin and histone enrichmentfor mass spectrometry (Catchet-MS) identifies IKZF1as a novel drug-able target for HIV-1 latency reversal

Ne, E.; Crespo, R.; Izquierdo-Lara, R.; Kocer, S.; Gorszka, A.; van Staveren, T.; Kan, T. W.; Dekkers, D. H. W.; Rokx, C.; Moulos, P.; Hatzis, P.; Palstra, R.-J.; Demmers, J. A.; Mahmoudi, T.

10.1101/2021.03.19.436149 — molecular biology — Posted on 2021-03-22

1677 Kupeantha yabassi (Coffeeae- Rubiaceae), a new Critically Endangered shrub species of the Ebo Forest area, Littoral Region, Cameroon

Alvarez, M. G.; Cheek, M.; Sonke, B.

10.1101/2021.03.21.436301 — plant biology — Posted on 2021-03-22

1678 Comparative repeat profiling of two closely related conifers (Larix decidua and Larix kaempferi) reveals high genome similarity with only one fast-evolving satellite DNA

Heitkam, T.; Schulte, L.; Weber, B.; Liedtke, S.; Breitenbach, S.; Kögler, A.; Morgenstern, K.; Brückner, M.; Tröber, U.; Wolf, H.; Krabel, D.; Schmidt, T.

10.1101/2021.03.21.436054 — plant biology — Posted on 2021-03-22

1679 Two interacting transcriptional coactivators cooperatively control plant immune responses

CHEN, H.; Li, M.; Qi, G.; Zhao, M.; Liu, L.; Zhang, J.; Chen, G.; Wang, D.; Liu, F.; Fu, Z.

10.1101/2021.03.21.436112 — plant biology — Posted on 2021-03-22

1680 From atoms to cells: bridging the gap between potency, efficacy, and safety of small molecules directed at a membrane protein

Aguayo-Ortiz, R.; Creech, J.; Jimenez-Vazquez, E. N.; Guerrero-Serna, G.; Wang, N.; Monteiro da Rocha, A.; Herron, T. J.; Espinoza-Fonseca, L. M.

10.1101/2021.03.19.432117 — pharmacology and toxicology — Posted on 2021-03-22

1681 Heterochromatin renewal after release from growth arrest controls genome-wide transcription re-activation in S.cerevisiae

Bhattacharjee, P. B.; Galic, H.; Hrgovcic, A.; Vasseur, P.; Radman-Livaja, M.

10.1101/603613 — molecular biology — Posted on 2021-03-22

1682 Screening for Potential Interaction Partners with Surface Plasmon Resonance Imaging Coupled to MALDI Mass Spectrometry

Anders, U.; Gulotti-Georgieva, M.; Zelger-Paulus, S.; Hibti, F.-E.; Frydman, C.; Suckau, D.; Sigel, R. K. O.; Zenobi, R.

10.1101/2020.05.07.082776 — molecular biology — Posted on 2021-03-22

1683 Machine-learning predicts genomic determinants of meiosis-driven structural variation in a eukaryotic pathogen

Badet, T.; Fouche, S.; Hartmann, F. E.; Zala, M.; Croll, D.

10.1101/2020.10.23.352468 — genomics — Posted on 2021-03-22

1684 Implementation and acceleration of optimal control for systems biology

Sharp, J. A.; Burrage, K.; Simpson, M. J.

10.1101/2021.03.17.435721 — systems biology — Posted on 2021-03-22

1685 DsbA is a redox-switchable mechanical chaperone

Eckels, E. C.; chaudhuri, d.; chakraborty, s.; Echelman, D. J.; Haldar, S.

10.1101/310169 — biophysics — Posted on 2021-03-22

1686 Moving pictures: Reassessing docking experiments with a dynamic view of protein interfaces

Prevost, C.; Sacquin-Mora, S.

10.1101/2020.12.08.415885 — biochemistry — Posted on 2021-03-22

1687 Nestmate recognition of early brood in ants

de Fouchier, A.; Leroy, C.; Khila, A.; d'Ettorre, P.

10.1101/2021.03.17.435807 — animal behavior and cognition — Posted on 2021-03-22

1688 Src activates retrograde membrane traffic through phosphorylation of GBF1

Chia, J.; Wang, S.; Wee, S.; Gill, D. J.; Tay, F.; Kannan, S.; Verma, C.; Gunaratne, J.; Bard, F.

10.1101/2020.08.02.233353 — cell biology — Posted on 2021-03-22

1689 Single cell gene fusion detection by scFusion

Jin, Z.; Huang, W.; Shen, N.; Li, J.; Wang, X.; Park, P. J.; Xi, R.

10.1101/2020.12.27.424506 — bioinformatics — Posted on 2021-03-21

1690 Conditional resampling improves calibration and sensitivity in single cell CRISPR screen analysis

Barry, T.; Wang, X.; Roeder, K.; Katsevich, E.

10.1101/2020.08.13.250092 — genomics — Posted on 2021-03-21

1691 Adaptive divergence in shoot gravitropism creates hybrid sterility in an Australian wildflower

Wilkinson, M. J.; Roda, F.; Walter, G. M.; James, M. E.; Nipper, R.; Walsh, J.; Allen, S. L.; North, H. L.; Beveridge, C. A.; Ortiz-Barrientos, D.

10.1101/845354 — evolutionary biology — Posted on 2021-03-21

1692 The Geometry of Concept Learning

Sorscher, B.; Ganguli, S.; Sompolinsky, H.

10.1101/2021.03.21.436284 — neuroscience — Posted on 2021-03-21

1693 Transcriptomic analysis of human and mouse muscle during hyperinsulinemia demonstrates insulin receptor downregulation as a mechanism for insulin resistance

Cen, H. H.; Botezelli, J. D.; Wang, S.; Noursadeghi, N.; Jessen, N.; Johnson, J. D.; Timmons, J. A.

10.1101/556571 — physiology — Posted on 2021-03-21

1694 Global Importance Analysis: An Interpretability Method to Quantify Importance of Genomic Features in Deep Neural Networks

Koo, P. K.; Majdandzic, A.; Ploenzke, M.; Anand, P.; Paul, S.

10.1101/2020.09.08.288068 — genomics — Posted on 2021-03-21

1695 Packing the Standard Genetic Code in its box: 3-dimensional late Crick wobble

Yarus, M.

10.1101/2021.01.18.427168 — evolutionary biology — Posted on 2021-03-21

1696 Extracellular vesicles produced by the human commensal gut bacterium Bacteroides thetaiotaomicron affect host immune pathways in a cell-type specific manner that are altered in inflammatory bowel disease

Gul, L.; Modos, D.; Fonseca, S.; Madgwick, M.; Thomas, J. P.; Sudhakar, P.; Stentz, R.; Carding, S. R.; Korcsmaros, T.

10.1101/2021.03.20.436262 — bioinformatics — Posted on 2021-03-21

1697 Genetic characteristics of Apodemus speciosus at Akiyoshidai Quasi-National Park in Yamaguchi Prefecture

Imai, H.; Tanaka, H.; Matsuo, T.; Miho, S.; Matsuya, S.; Hyoto, M.; Kano, K.; Kusakabe, K. T.

10.1101/2021.03.21.436340 — genetics — Posted on 2021-03-21

1698 Constructing phylogenetic relationship based on the independent selection law of genome sequences

Li, X.; Li, H.; Yang, Z.; Zhang, Z.

10.1101/2021.03.20.436244 — evolutionary biology — Posted on 2021-03-21

1699 Ribosomal RNA methylation by GidB is a capacitor for discrimination of mischarged tRNA

Bi, Z.; Su, H.; Hong, J.; Javid, B.

10.1101/2021.03.02.433644 — molecular biology — Posted on 2021-03-21

1700 Fusion of the N-terminal 119 amino acids with the RelA-CTD renders its growth inhibitory effects (p)ppGpp-dependent

Pohnerkar, J.; Tailor, K.; Sagar, P.; Dave, K.

10.1101/2021.03.21.436043 — microbiology — Posted on 2021-03-21

1701 The E3 ubiquitin ligase RNF216/TRIAD3 is a central regulator of the hypothalamic-pituitary-gonadal axis

George, A. J.; Hoffiz, Y. C.; Ware, C.; Dong, B.; Fang, N.; Hrabovszky, E.; Mabb, A. M.

10.1101/2021.03.21.436306 — neuroscience — Posted on 2021-03-21

1702 Human gaze is precisely aligned with the foveolar cone topography of both eyes

Reiniger, J. L.; Domdei, N.; Holz, F. G.; Harmening, W. M.

10.1101/2021.03.19.436115 — neuroscience — Posted on 2021-03-21

1703 Prediction errors for aversive events shape long-term memory formation through a distinct neural mechanism

Kalbe, F.; Schwabe, L.

10.1101/2021.03.19.436177 — neuroscience — Posted on 2021-03-21

1704 Biophysical basis of cellular multi-specificity encoded in a model molecular switch

Perica, T.; Mathy, C. J. P.; Xu, J.; Jang, G. M.; Zhang, Y.; Kaake, R.; Ollikainen, N.; Braberg, H.; Swaney, D. L.; Lambright, D. G.; Kelly, M. J. S.; Krogan, N. J.; Kortemme, T.

10.1101/2020.01.04.893909 — systems biology — Posted on 2021-03-21

1705 Bacterial-type plant ferroxidases tune local phosphate sensing in root development

Naumann, C.; Heisters, M.; Brandt, W.; Janitza, P.; Alfs, C.; Tang, N.; Nienguesso, A. T.; Ziegler, J.; Imre, R.; Mechtler, K.; Dagdas, Y.; Hoehenwarter, W.; Sawers, G.; Quint, M.; Abel, S.

10.1101/2021.03.19.436157 — plant biology — Posted on 2021-03-21

1706 Combined Inhibition of SHP2 and CXCR1/2 Promotes Anti-Tumor T Cell Response in NSCLC

Tang, K. H.; Li, S.; Khodadadi-Jamayran, A.; Jen, J.; Han, H.; Guidry, K.; Chen, T.; Hao, Y.; Fedele, C.; Zebala, J.; Maeda, D.; Christensen, J.; Olson, P.; Athanas, A.; Wong, K.-K.; Neel, B. G.

10.1101/2021.03.21.436338 — cancer biology — Posted on 2021-03-21

1707 Thiamin-Diphosphate Enzymes Are an Ancient Family of Repeat Proteins

Merski, M.; Gorna, M.

10.1101/2021.03.21.436335 — biophysics — Posted on 2021-03-21

1708 Human genetic analyses of organelles highlight the nucleus, but not the mitochondrion, in age-related trait heritability

Gupta, R.; Karczewski, K. J.; Howrigan, D.; Neale, B. M.; Mootha, V. K.

10.1101/2021.01.22.427431 — genomics — Posted on 2021-03-21

1709 Genomic sequencing confirms absence of introgression despite past hybridisation between a common and a critically endangered bird

Forsdick, N. J.; Martini, D.; Brown, L.; Maloney, R. F.; Steeves, T. E.; Knapp, M.

10.1101/2020.09.28.316299 — genomics — Posted on 2021-03-21

1710 Cross-tissue eQTL mapping in the presence of missing data via surrogate outcome analysis

McCaw, Z. R.; Gaynor, S. M.; Sun, R.; Lin, X.

10.1101/2020.11.29.403063 — genetics — Posted on 2021-03-21

1711 Rotavirus A Genome Segments Show Distinct Segregation and Codon Usage Patterns

Hoxie, I.; Dennehy, J. J.

10.1101/2021.03.20.436270 — evolutionary biology — Posted on 2021-03-21

1712 Gastruloids as in vitro models of embryonic blood development with spatial and temporal resolution

Rossi, G.; Giger, S.; Huebscher, T.; Lutolf, M. P.

10.1101/2021.03.21.436320 — developmental biology — Posted on 2021-03-21

1713 Acriflavine, a clinically aproved drug, inhibits SARS-CoV-2 and other betacoronaviruses

Napolitano, V.; Dabrowska, A.; Schorpp, K.; Mourao, A.; Barreto-Duran, E.; Benedyk, M.; Botwina, P.; Brandner, S.; Bostock, M.; Chykunova, Y.; Czarna, A.; Dubin, G.; Frohlich, T.; Hoelscher, M.; Jedrysik, M.; Matsuda, A.; Owczarek, K.; Pachota, M.; Plettenburg, O.; Potempa, J.; Rothenaigner, I.; Schlauderer, F.; Szczepanski, A.; Mohn, K. G.-I.; Blomberg, B.; Sattler, M.; Hadian, K.; Popowicz, G. M.; Pyrc, K.

10.1101/2021.03.20.436259 — microbiology — Posted on 2021-03-21

1714 Predicting potentially permissive substitutions that improve the fitness of A(H1N1)pdm09 viruses bearing the H275Y NA substitution

Farrukee, R.; Gunalan, V.; Maurer-Stroh, S.; Reading, P. C.; Hurt, A. C.

10.1101/2021.03.21.436293 — microbiology — Posted on 2021-03-21

1715 Anti-GD2 antibody disrupts GD2:Siglec-7 interactions and synergizes with CD47 blockade to mediate tumor eradication

Theruvath, J.; Menard, M.; Smith, B. A.; Linde, M. H.; Coles, G.; Wu, W.; Kiru, L.; Delaidelli, A.; Silberstein, J. L.; Banuelos, A.; Dhingra, S.; Sotillo, E.; Heitzeneder, S.; Tousley, A.; Lattin, J.; Xu, P.; Huang, J.; Nasholm, N.; Dalton, G. N.; He, A.; Kuo, T. C.; Sangalang, E. R. B.; Pons, J.; Barkal, A.; Brewer, R.; Marjon, K. D.; Marshall, P. L.; Fernandes, R.; Cochran, J.; Sorensen, P.; Daldrup-Link, H. E.; Weissman, I. L.; Sage, J.; Majeti, R.; Bertozzi, C. R.; Weiss, W. A.; Mackall, C. L.; Majzner, R. G.

10.1101/2021.03.19.436221 — immunology — Posted on 2021-03-21

1716 Ion transport modulators differentially modulate inflammatory responses in THP-1 derived macrophages

Mitini-Nkhoma, S. C.; Fernando, N.; Ishaka, G. K. D.; Handunnetti, S. M.; Pathirana, S. L.

10.1101/2021.03.21.436302 — immunology — Posted on 2021-03-21

1717 Dram1 confers resistance to Salmonella infection

Masud, S.; Zhang, R.; Prajsnar, T. K.; Meijer, A. H.

10.1101/2021.03.21.436194 — immunology — Posted on 2021-03-21

1718 UNC-45A is Highly Expressed in the Proliferative Cells of the Mouse Genital Tract and in the Microtubule-Rich Areas of the Mouse Nervous System

Bazzaro, M.; Clemente, V.; Hoshino, A.; Meints, J.; Starr, T.; Lee, M.

10.1101/2021.03.19.436218 — neuroscience — Posted on 2021-03-21

1719 Non-REM sleep in major depressive disorder

Bovy, L.; Weber, F. D.; Tendolkar, I.; Fernandez, G.; Czisch, M.; Steiger, A.; Zeising, M.; Dresler, M.

10.1101/2021.03.19.436132 — neuroscience — Posted on 2021-03-21

1720 A New Old Tale: Dopamine Transporter implications in an animal model of Attention-Deficit Hyperactivity Disorder

Fernandez, G.; Krapacher, F.; Ferreras, S.; Quasollo, G.; Mari, M. M.; Pisano, M. V.; Montemerlo, A.; Rubianes, M. D.; Bregonzio, C.; Arias, C.; Paglini, M. G.

10.1101/2021.03.19.436226 — neuroscience — Posted on 2021-03-21

1721 Structural and energetic profiling of SARS-CoV-2 antibody recognition and the impact of circulating variants

Yin, R.; Guest, J. D.; Taherzadeh, G.; Gowthaman, R.; Mittra, I.; Quackenbush, J.; Pierce, B. G.

10.1101/2021.03.21.436311 — microbiology — Posted on 2021-03-21

1722 Critical interactions for SARS-CoV-2 spike protein binding to ACE2 identified by machine learning

Pavlova, A.; Zhang, Z.; Acharya, A.; Lynch, D. L.; Pang, Y. T.; Mou, Z.; Parks, J. M.; Chipot, C.; Gumbart, J. C.

10.1101/2021.03.19.436231 — biophysics — Posted on 2021-03-21

1723 Circadian regulation of SARS-CoV-2 infection in lung epithelial cells

Zhuang, X.; Tsukuda, S.; Wrensch, F.; Wing, P. A.; Borrmann, H.; Harris, J. M.; Morgan, S. B.; Mailly, L.; Thakur, N.; Conceicao, C.; Sanghani, H.; Heydmann, L.; Bach, C.; Ashton, A.; Walsh, S.; Tan, T. K.; Schimanski, L.; Huang, K.-Y. A.; Schuster, C.; Watashi, K.; Hinks, T. S.; Jagannath, A.; Vausdevan, S. R.; Bailey, D.; Baumert, T. F.; McKeating, J. A.

10.1101/2021.03.20.436163 — microbiology — Posted on 2021-03-21

1724 Interferon Resistance of Emerging SARS-CoV-2 Variants

Guo, K.; Barrett, B. S.; Mickens, K. L.; Hasenkrug, K. J.; Santiago, M.

10.1101/2021.03.20.436257 — microbiology — Posted on 2021-03-21

1725 A bispecific monomeric nanobody induces SARS-COV-2 spike trimer dimers

Hanke, L.; Das, H.; Sheward, D.; Perez Vidakovics, L.; Urgard, E.; Moliner Morro, A.; Karl, V.; Pankow, A.; Changil, K.; Smith, N.; Pedersen, G.; Coquet, J. M.; Hallberg, B. M.; Murrell, B.; McInerney, G. M.

10.1101/2021.03.20.436243 — immunology — Posted on 2021-03-21

1726 From GWAS Variant to Function: a Study of ~148,000 Variants for Blood Cell Traits.

Sun, Q.; Crowley, C. A.; Huang, L.; Wen, J.; Chen, J.; Bao, E. L.; Auer, P.; Lettre, G.; Reiner, A. P.; Sankaran, V. G.; Raffield, L. M.; Li, Y.

10.1101/2021.02.16.431409 — genetics — Posted on 2021-03-21

1727 The chemotherapeutic drug methotrexate selects for antibiotic resistance

Guthmundsdottir, J. S.; Fredheim, E. G. A.; Koumans, C. I. M.; Hegstad, J.; Tang, P.-C.; Andersson, D. I.; Samuelsen, O.; Johnsen, P. J.

10.1101/2020.11.12.378059 — microbiology — Posted on 2021-03-21

1728 REAP: A platform to identify autoantibodies that target the human exoproteome

Wang, E. Y.; Dai, Y.; Rosen, C. E.; Schmitt, M. M.; Dong, M. X.; Ferre, E. M. N.; Liu, F.; Yang, Y.; Gonzalez-Hernandez, J. A.; Meffre, E.; Hinchcliffe, M.; Koumpouras, F.; Lionakis, M. S.; Ring, A. M.

10.1101/2021.02.11.430703 — immunology — Posted on 2021-03-21

1729 Systemic and mucosal mobilization of granulocyte subsets during lentivirus infection

Jones, R.; Manickam, C.; Ram, D. R.; Kroll, K.; Hueber, B.; Woolley, G.; Shah, S. V.; Smith, S.; Varner, V.; Reeves, R. K.

10.1101/2021.03.19.436235 — immunology — Posted on 2021-03-21

1730 Paradoxical relationship between speed and accuracy in olfactory figure-background segregation

Lebovich, L.; Yunerman, M.; Scaiewicz, V.; Loewenstein, Y.; Rokni, D.

10.1101/2021.03.10.434790 — neuroscience — Posted on 2021-03-21

1731 Marchantia polymorpha model reveals conserved infection mechanisms in the vascular wilt fungal pathogen Fusarium oxysporum

Redkar, A.; Gimenez Ibanez, S.; Sabale, M.; Zechmann, B.; Solano, R.; Di Pietro, A.

10.1101/2021.03.20.436100 — plant biology — Posted on 2021-03-21

1732 CrowdGO: machine learning and semantic similarity guided consensus Gene Ontology annotation

Reijnders, M. J.; Waterhouse, R. M.

10.1101/731596 — bioinformatics — Posted on 2021-03-21

1733 Improving the efficiency of de Bruijn graph construction using compact universal hitting sets

Ben-Ari, Y.; Flomin, D.; Pu, L.; Orenstein, Y.; Shamir, R.

10.1101/2020.11.08.373050 — bioinformatics — Posted on 2021-03-21

1734 Oct1 recruits the histone lysine demethylase Utx to canalize lineage specification

Perovanovic, J.; Wu, Y.; Shen, Z.; Chandrasekharan, M. B.; Tantin, D.

10.1101/2020.12.01.406488 — developmental biology — Posted on 2021-03-21

1735 The interaction between endogenous GABA, functional connectivity and behavioral flexibility is critically altered with advanced age

Heise, K.-F.; Rueda Delgado, L. M.; Chalavi, S.; King, B. R.; Santos Monteiro, T.; Edden, R. A. E.; Mantini, D.; Swinnen, S. P.

10.1101/2020.10.08.331637 — neuroscience — Posted on 2021-03-21

1736 Seqpac: A New Framework for small RNA analysis in R using Sequence-Based Counts

Skog, S.; Orkenby, L.; Tariq, K.; Ostlund Farrants, A.-K.; Ost, A.; Natt, D.

10.1101/2021.03.19.436151 — bioinformatics — Posted on 2021-03-21

1737 Predicting activatory and inhibitory drug-target interactions based on mol2vec and genetically perturbed transcriptomes

Lee, W.-Y.; Lee, C.-Y.; Kim, C.-E.

10.1101/2021.03.18.436088 — bioinformatics — Posted on 2021-03-21

1738 Spatial arrangement and biofertilizers enhance the performance of legume-millet intercropping system in rainfed areas of southern India

Singh, D.; Mathimaran, N.; Sekar, J.; Ramalingam, P. V.; Perisamy, Y.; Raju, K.; Raj, R.; King, I. O.; Nanjundegowda, T. M.; Narayanswamy, M. B.; Chikkegowda, B. N.; Siddegowda, S. M.; Bagyaraj, D. J.; Maeder, P.; Boller, T.; Kahmen, A.

10.1101/2020.11.20.387886 — ecology — Posted on 2021-03-21

1739 Topoisomerase 1 dependent R-loop deficiency drives accelerated replication and genomic instability

Sarni, D.; Shtrikman, A.; Oren, Y. S.; Kerem, B.

10.1101/2020.07.21.214700 — cell biology — Posted on 2021-03-21

1740 Genome sequencing and morphometric analysis of alpine bumblebees experiencing climate change reveal ongoing phenotypic shifts and a lack of population structure

Christmas, M. J.; Jones, J. C.; Olsson, A.; Wallerman, O.; Bunikis, I.; Kierczak, M.; Whitley, K. M.; Sullivan, I.; Geib, J. C.; Miller-Struttmann, N. E.; Webster, M. T.

10.1101/2021.03.17.435598 — evolutionary biology — Posted on 2021-03-21

1741 SC1: A Tool for Interactive Web-Based Single Cell RNA-Seq Data Analysis

Moussa, M.; Mandoiu, I.

10.1101/2021.03.19.435534 — bioinformatics — Posted on 2021-03-20

1742 ChromWave: Deciphering the DNA-encoded competition between transcription factors and nucleosomes with deep neural networks

Cakiroglu, S. A.; Steinhauser, S.; Smith, J.; Xing, W.; Luscombe, N. M.

10.1101/2021.03.19.436198 — genomics — Posted on 2021-03-20

1743 Analysis of correlation and trail coefficients for componentperformance s in nine experimental tomato lines

QUISPE CHOQUE, G.

10.1101/2021.03.18.436039 — genetics — Posted on 2021-03-20

1744 Evolutionary conserved protein motifs drive attachment of the plant nucleoskeleton at nuclear pores

MERMET, S.; Voisin, M.; Mordier, J.; Dubos, T.; Tutois, S.; Tuffery, P.; Baroux, C.; Tamura, K.; Probst, A. V.; VANROBAYS, E.; tatout, c.

10.1101/2021.03.20.435662 — genetics — Posted on 2021-03-20

1745 Foxes facilitate other wildlife through ecosystem engineering activities on the Arctic tundra

Zhao, S.-T.; Johnson-Bice, S. M.; Roth, J. D.

10.1101/2021.03.19.436172 — ecology — Posted on 2021-03-20

1746 More pests but less treatments: ambivalent effect of landscape complexity on Conservation Biological Control

Zamberletti, P.; Sabir, K.; Opitz, T.; Bonnefon, O.; Gabriel, E.; Papaix, J.

10.1101/2021.03.19.436155 — ecology — Posted on 2021-03-20

1747 Internal microbial zonation assists in the massive growth of marimo, a lake ball of Aegagropila linnaei in Lake Akan

Nakai, R.; Wakana, I.; Niki, H.

10.1101/2021.03.20.434239 — microbiology — Posted on 2021-03-20

1748 γδ-Thymocyte Maturation and Emigration

Joannou, K.; Golec, D. P.; Wang, H.; Henao-Caviedes, L. M.; May, J. F.; Kelly, R. G.; Chan, R.; Jameson, S. C.; Baldwin, T. A.

10.1101/2021.03.19.435877 — immunology — Posted on 2021-03-20

1749 Automated Spatially Targeted Optical Micro Proteomics (AutoSTOMP) 2.0 identifies proteins enriched within inflammatory lesions in tissue sections and human clinical biopsies.

YIN, B.; Caggiano, L. R.; Li, R.-C.; McGowan, E.; Holmes, J. W.; Ewald, S. E.

10.1101/2021.03.19.436192 — immunology — Posted on 2021-03-20

1750 Impact of anaesthesia on static and dynamic functional connectivity in mice

Tsurugizawa, T.; Yoshimaru, D.

10.1101/2021.03.18.436098 — neuroscience — Posted on 2021-03-20

1751 A Weighted Network Analysis Framework for the Hourglass Effect - and its Application in the C. Elegans Connectome

Batta, I.; Yao, Q.; Sabrin, K. M.; Dovrolis, C.

10.1101/2021.03.19.436224 — neuroscience — Posted on 2021-03-20

1752 Auditory mismatch responses are differentially sensitive to changes in muscarinic acetylcholine versus dopamine receptor function

Weber, L. A.; Tomiello, S.; Schoebi, D.; Wellstein, K. V.; Mueller, D.; Iglesias, S.; Stephan, K. E.

10.1101/2021.03.18.435979 — neuroscience — Posted on 2021-03-20

1753 A digitization theory of the Weber-Fechner law

Choe, H.

10.1101/2021.03.15.435555 — neuroscience — Posted on 2021-03-20

1754 Vision-to-value transformations in artificial network and human brains

Pham, T. Q.; Yoshimoto, T.; Niwa, H.; Takahashi, H. K.; Uchiyama, R.; Matsui, T.; Anderson, A. K.; Sadato, N.; Chikazoe, J.

10.1101/2021.03.18.435929 — neuroscience — Posted on 2021-03-20

1755 Bridging cell-scale simulations and radiologic images to explain short-time intratumoral oxygen fluctuations

Kingsley, J. L.; Costello, J. R.; Raghunand, N.; Rejniak, K. A.

10.1101/2021.03.18.435990 — systems biology — Posted on 2021-03-20

1756 Optimal Transport improves cell-cell similarity inference in single-cell omics data

Huizing, G.-J.; Peyre, G.; Cantini, L.

10.1101/2021.03.19.436159 — systems biology — Posted on 2021-03-20

1757 Inferring causality in biological oscillators

Tyler, J.; Forger, D.; Kim, J. K.

10.1101/2021.03.18.435997 — systems biology — Posted on 2021-03-20

1758 JASMONIC ACID PRIMING OF POTATO USES HYPERSENSITIVE RESPONSE-DEPENDENT DEFENSE AND DELAYS NECROTROPHIC PHASE CHANGE AGAINST PHYTOPHTHORA INFESTANS

Arevalo-Marin, D. F.; Briceno, D. M.; Mosquera Vasquez, T.; Melgarejo, L. M.; Sarmiento, F.

10.1101/2021.03.19.436215 — plant biology — Posted on 2021-03-20

1759 EffectorO: motif-independent prediction of effectors in oomycete genomes using machine learning and lineage specificity

Nur, M. J.; Wood, K. J.; Michelmore, R. W.

10.1101/2021.03.19.436227 — plant biology — Posted on 2021-03-20

1760 Loss of Endothelial HIF-Prolyl hydroxylase 2 (PHD2) Induces Cardiac Hypertrophy and Fibrosis

Dai, Z.; Cheng, J.; Liu, B.; Yi, D.; Feng, A.; Wang, T.; Gao, C.; Wang, Y.; Zhu, M. M.; Zhang, X.; Zhao, Y.

10.1101/2021.03.19.434301 — physiology — Posted on 2021-03-20

1761 Membrane-MEDYAN: Simulating Deformable Vesicles Containing Complex Cytoskeletal Networks

Ni, H.; Papoian, G.

10.1101/2021.03.19.436229 — biophysics — Posted on 2021-03-20

1762 The Aliment to Bodily Condition knowledgebase (ABCkb): A database connecting plants and human health

Trautman, A.; Linchangco, R.; Walstead, R.; Jay, J. J.; Brouwer, C.

10.1101/2021.03.20.436160 — bioinformatics — Posted on 2021-03-20

1763 Predicting activatory and inhibitory drug-target interactions based on mol2vec and genetically perturbed transcriptomes

Lee, W.-Y.; Lee, C.-Y.; Kim, C.-E.

10.1101/2021.03.18.436088 — bioinformatics — Posted on 2021-03-20

1764 Predicting TCR-epitope Binding Specificity Using Deep Metric Learning and Multimodal Learning

Luu, A.; Leistico, J. R.; Miller, T.; Kim, S.; Song, J. S.

10.1101/2021.03.19.436191 — bioinformatics — Posted on 2021-03-20

1765 Correcting for Background Noise Improves Phenotype Prediction from Human Gut Microbiome Data

Briscoe, L.; Balliu, B.; Sankararaman, S.; Halperin, E.; Garud, N. R.

10.1101/2021.03.19.436199 — bioinformatics — Posted on 2021-03-20

1766 Machine learning prediction of Antibody-Antigen binding: dataset, method and testing

Ye, C.; Hu, W.; Gaeta, B.

10.1101/2021.03.19.435772 — bioinformatics — Posted on 2021-03-20

1767 Isolation, Molecular identification, Molecular docking In Vitro and In Silico Evaluation study against Fusarium oxysporum sp. Lactucae

Shamkh, I. M.; Pratiwi, D.; El faki, A. S.

10.1101/2021.03.19.436165 — bioinformatics — Posted on 2021-03-20

1768 GproDIA enables data-independent acquisition glycoproteomics with comprehensive statistical control

Yang, Y.; Cao, W.; Yan, G.; Kong, S.; Wu, M.; Yang, P.; Qiao, L.

10.1101/2021.03.20.436117 — bioinformatics — Posted on 2021-03-20

1769 Cellar: Interactive single cell data annotation tool

Hasanaj, E.; Wang, J.; Sarathi, A.; Ding, J.; Bar-Joseph, Z.

10.1101/2021.03.19.436162 — bioinformatics — Posted on 2021-03-20

1770 Representation learning of RNA velocity reveals robust cell transitions

Qiao, C.; Huang, Y.

10.1101/2021.03.19.436127 — bioinformatics — Posted on 2021-03-20

1771 Convergent Usage of Amino Acids in Human Cancers as a Reversed Process of Tissue Development

Luo, Y.; Liang, H.

10.1101/2021.03.18.436083 — bioinformatics — Posted on 2021-03-20

1772 Asc-Seurat - Analytical single-cell Seurat-based web application

Pereira, W. J.; de Almeida, F. M.; Balmant, K. M.; Conde, D.; Triozzi, P. M.; Schmidt, H. W.; Dervinis, C.; Pappas, G. J.; Kirst, M.

10.1101/2021.03.19.436196 — bioinformatics — Posted on 2021-03-20

1773 An equine tendon model for studying intra-tendinous shear in tendons that have more than one muscle contribution

Yin, N.-H.; McCarthy, I.; Birch, H.

10.1101/2021.03.19.436206 — bioengineering — Posted on 2021-03-20

1774 Platinized graphene fiber electrodes revealed differential activity in terminal splenic neurovascular plexi supporting a direct spleen-vagus communication

Gonzalez-Gonzalez, M. A.; Bendale, G.; Wang, K.; Wallace, G. G.; Romero-Ortega, M. I.

10.1101/2021.03.19.436189 — bioengineering — Posted on 2021-03-20

1775 Beyond single discrete responses: An integrative and multidimensional analysis of behavioral dynamics assisted by Machine Learning

Leon, A.; Hernandez, V.; Lopez, J.; Guzman, I.; Quintero, V.; Toledo, P.; Avendano-Garrido, M. L.; Hernandez-Linares, C.; Escamilla, E.

10.1101/2021.03.17.435751 — animal behavior and cognition — Posted on 2021-03-20

1776 Multimodal characterization of Yucatan minipig behavior and physiology through maturation

Netzley, A. H.; Hunt, R. D.; Franco-Arellano, J.; Arnold, N.; Munoz, K. A.; Colbath, A. C.; Bush, T. R.; Pelled, G.

10.1101/2021.03.18.436053 — animal behavior and cognition — Posted on 2021-03-20

1777 Bumblebees can detect floral humidity

Harrap, M.; Hempel de Ibarra, N.; Knowles, H. D.; Whitney, H. M.; Rands, S. A.

10.1101/2021.03.19.436119 — animal behavior and cognition — Posted on 2021-03-20

1778 Tardigrades exhibit robust inter-limb coordination across walking speeds

Nirody, J. A.; Duran, L. A.; Johnston, D.; Cohen, D. J.

10.1101/2021.03.19.436228 — animal behavior and cognition — Posted on 2021-03-20

1779 Optogenetic manipulation of individual or whole population Caenorhabditis elegans worms with an under hundred-dollar tool: the OptoArm

Koopman, M.; Janssen, L.; Nollen, E.

10.1101/2021.03.19.435933 — genetics — Posted on 2021-03-20

1780 Assortative Mating Biases Marker-based Heritability Estimators

Border, R.; O'Rourke, S.; de Candia, T.; Goddard, M. E.; Visscher, P. M.; Yengo, L.; Jones, M.; Keller, M. C.

10.1101/2021.03.18.436091 — genetics — Posted on 2021-03-20

1781 APOE4 is associated with elevated blood lipids and lower levels of innate immune biomarkers in a tropical Amerindian subsistence population

Garcia, A. R.; Finch, C.; Gatz, M.; Kraft, T.; Cummings, D.; Charifson, M.; Eid Rodriguez, D.; Buetow, K.; Beheim, B. A.; Allayee, H.; Thomas, G. S.; Stieglitz, J.; Gurven, M.; Kaplan, H.; Trumble, B.

10.1101/2021.03.19.436070 — evolutionary biology — Posted on 2021-03-20

1782 Multilevel selection favors fragmentation modes that maintain cooperative interactions in multispecies communities

Henriques, G. J. B.; van Vliet, S.; Doebeli, M.

10.1101/2021.03.18.436065 — evolutionary biology — Posted on 2021-03-20

1783 Growth of Lahontan Cutthroat Trout from multiple sources re-introduced into Sagehen Creek, CA

Stead, J. E.; Boucher, V. L.; Moyle, P. B.; Rypel, A. L.

10.1101/2021.03.18.436085 — ecology — Posted on 2021-03-20

1784 A strategic sampling design revealed the local genetic structure of cold-water fluvial sculpin: a focus on groundwater-dependent water temperature heterogeneity

Nakajima, S.; Sueyoshi, M.; Hirota, S. K.; Ishiyama, N.; Matsuo, A.; Suyama, Y.; Nakamura, F.

10.1101/2021.03.19.435938 — ecology — Posted on 2021-03-20

1785 Water yield modelling, sensitivity analysis and validation: a study for Portugal

Almeida, B.; Cabral, P.

10.1101/2021.03.20.433030 — ecology — Posted on 2021-03-20

1786 Effects of cover crops on beetle assemblages in tea plantations

Chen, L.-L.; Pozsgai, G.; Li, X.-Y.; Li, L.; Reddy, G. V. P.; You, M.-S.

10.1101/2021.03.19.436210 — ecology — Posted on 2021-03-20

1787 Marchantia polymorpha model reveals conserved infection mechanisms in the vascular wilt fungal pathogen Fusarium oxysporum

Redkar, A.; Gimenez Ibanez, S.; Sabale, M.; Zechmann, B.; Solano, R.; Di Pietro, A.

10.1101/2021.03.20.436100 — plant biology — Posted on 2021-03-20

1788 Moment-based approximations for the Wright-Fisher model of population dynamics under natural selection at two linked loci

He, Z.; Lyu, W.; Beaumont, M. A.; Yu, F.

10.1101/2021.01.01.424882 — genetics — Posted on 2021-03-20

1789 Gallic Acid, a Methyl 3,4-Dihydroxybenzoate Derivative, Induces Neural Stem Cells to Differentiate and Proliferate

Jiang, J.; Liu, W.; Hai, J.; Luo, Y.; Chen, K.; Xin, Y.; Pan, J.; Hu, Y.; Gao, Q.; Xiao, F.; Luo, H.

10.1101/2021.03.01.433474 — neuroscience — Posted on 2021-03-20

1790 Comparison between slow, anisotropic LE4PD fluctuations and thePrincipal Component Analysis modes of Ubiquitin

Beyerle, E. R.; Guenza, M. G.

10.1101/2021.01.06.425617 — biophysics — Posted on 2021-03-20

1791 SPICEMIX: Integrative single-cell spatial modeling for inferring cell identity

Chidester, B.; Zhou, T.; Ma, J.

10.1101/2020.11.29.383067 — bioinformatics — Posted on 2021-03-20

1792 Generation of Drosophila attP containing cell lines using CRISPR-Cas9

Zelhof, A. C.; Mariyappa, D.; Luhur, A.; Overton, D.

10.1101/2021.03.19.436223 — genetics — Posted on 2021-03-20

1793 A non-canonical microRNA derived from the snaR-A non-coding RNA targets a metastasis inhibitor

Stribling, D.; Lei, Y.; Guardia, C. M.; Li, L.; Fields, C. J.; Nowialis, P.; Opavsky, R.; Renne, R.; Xie, M.

10.1101/2021.03.20.436234 — molecular biology — Posted on 2021-03-20

1794 Coupling of spliceosome complexity to intron diversity

Sales-Lee, J.; Perry, D. S.; Bowser, B. A.; Diedrich, J. K.; Rao, B.; Beusch, I.; Yates, J. R.; Roy, S. W.; Madhani, H. D.

10.1101/2021.03.19.436190 — molecular biology — Posted on 2021-03-20

1795 Application of HPMCAS-coated Ctx(Ile21)-Ha peptide microparticles as a potential use to prevent systemic infection caused by Salmonella Enteritidis in poultry

Roque Borda, C. A.; de Mesquita Souza Saraiva, M.; F. M. Monte, D.; Rodrigues Alves, L. B.; de Almeida, A. M.; Santiago Ferreira, T.; Spina de Lima, T.; Pereira Benevides, V.; Memrava Cabrera, J.; Meneguin, A. B.; Chorilli, M.; Berchieri Junior, A.; Vicente, E. F.

10.1101/2021.03.19.436179 — microbiology — Posted on 2021-03-20

1796 Proteus mirabilis employs a contact-dependent killing system against competing Enterobacteriaceae

Kiani, D.; Santus, W.; Kiernan, K. A.; Behnsen, J.

10.1101/2021.03.19.436238 — microbiology — Posted on 2021-03-20

1797 The within-host evolutionary dynamics of seasonal and pandemic human influenza A viruses in young children

Han, A. X.; Felix Garza, Z. C.; Welkers, M. R. A.; Vigeveno, R. M.; Tran, N. D.; Le, T. Q. M.; Pham, Q. T.; Tran, T. N. A.; Ha, M. T.; Nguyen, T. H.; Le, Q. T.; Le, T. H.; Hoang, T. B. N.; Chokephaibulkit, K.; Puthavathana, P.; Nguyen, V. V. C.; Nghiem, M. N.; Tran, T. H.; Wertheim, H. F. L.; Horby, P.; Fox, A.; van Doorn, H. R.; Eggink, D.; de Jong, M. D.; Russell, C. A.

10.1101/2021.03.20.436248 — microbiology — Posted on 2021-03-20

1798 GABAergic signaling in human and murine NK cells upon challenge with Toxoplasma gondii

Bhandage, A. K.; Friedrich, L. M.; Kanatani, S.; Jakobsson-Bjoerken, S.; Escrig-Larena, J. I.; Wagner, A. K.; Chambers, B. J.; Barragan, A.

10.1101/2021.03.19.435611 — immunology — Posted on 2021-03-20

1799 The Human Milk Oligosaccharide 3-Sialyllactose Promotes Inflammation Resolution and Reduces Atherosclerosis Development in Mice.

Pessentheiner, A. R.; Spann, N. J.; Autran, C. A.; Ramms, B.; Chiang, A. W. T.; Grunddal, K. V.; Wang, Y.; Quach, A.; Booshehri, L. M.; Hammond, A.; Tognaccini, C.; Latasiewicz, J.; Witztum, j. L.; Hoffman, H. M.; Lewis, N. E.; Glass, C. K.; Bode, L.; Gordts, P. L. S. M.

10.1101/2021.03.19.433472 — immunology — Posted on 2021-03-20

1800 Plasticity in gustatory and nociceptive neurons controls decision making in C. elegans salt navigation

Dekkers, M. P. J.; Salfelder, F.; Sanders, T.; Umuerri, O.; Cohen, N.; Jansen, G.

10.1101/2021.03.19.436114 — neuroscience — Posted on 2021-03-20

1801 A bidirectional corticoamygdala circuit for the encoding and retrieval of detailed reward memories

Sias, A. C.; Morse, A. K.; Wang, S.; Greenfield, V. Y.; Goodpaster, C. M.; Wrenn, T. M.; Wikenheiser, A. M.; Holley, S. M.; Cepeda, C.; Levine, M. S.; Wassum, K. M.

10.1101/2021.03.20.436233 — neuroscience — Posted on 2021-03-20

1802 An atlas of inter- and intra-tumor heterogeneityof apoptosis competency in colorectal cancertissue at single cell resolution

10.1101/2021.03.19.436184 — cancer biology — Posted on 2021-03-20

1803 DNA Supercoiling Drives a Transition between Collective Modes of Gene Synthesis

Chatterjee, P.; Goldenfeld, N.; Kim, S.

10.1101/2021.03.19.436182 — biophysics — Posted on 2021-03-20

1804 The middle lipin (M-Lip) domain is a new dimeric protein fold that binds membranes

Gu, W.; Gao, S.; Wang, H.; Fleming, K. D.; Hoffmann, R. M.; Yang, J. W.; Patel, N. M.; Choi, Y. M.; Burke, J. E.; Reue, K.; Airola, M. V.

10.1101/2021.03.19.436211 — biochemistry — Posted on 2021-03-20

1805 A multiplex microchamber diffusion assay for the antibody-based detection of microRNAs on randomly ordered microbeads

Geithe, C.; Zeng, B.; Schmidt, C.; Dinter, F.; Roggenbuck, D.; Lehmann, W.; Dame, G.; Schierack, P.; Hanack, K.; Rödiger, S.

10.1101/2021.03.19.436219 — biochemistry — Posted on 2021-03-20

1806 Molecular basis for recognition of the Group A Carbohydrate backbone by the PlyC streptococcal bacteriophage endolysin

King, H.; Ajay Castro, S.; Bueren-Calabuig, J.; Arunrao Pohane, A.; Scholte, C. M.; Fischetti, V. A.; Korotkova, N.; Zuccotto, F.; Nelson, D. C.; Dorfmueller, H. C.

10.1101/2021.03.19.436156 — biochemistry — Posted on 2021-03-20

1807 Transcriptome-wide spatial RNA profiling maps the cellular architecture of the developing human neocortex

Roberts, K.; Aivazidis, A.; Kleshchevnikov, V.; Li, T.; Fropf, R.; Rhodes, M.; Beechem, J. M.; Hemberg, M.; Bayraktar, O.

10.1101/2021.03.20.436265 — genomics — Posted on 2021-03-20

1808 Revisiting the source of wilt symptoms: X-ray microcomputed tomography provides direct evidence that Ralstonia biomass clogs xylem vessels.

Ingel, B.; Caldwell, D.; Duong, F.; Parkinson, D. Y.; McCulloh, K. A.; Iyer-Pascuzzi, A. S.; McElrone, A. J.; Lowe-Power, T. M.

10.1101/2021.03.19.436187 — microbiology — Posted on 2021-03-20

1809 Deciphering Bedaquiline and Clofazimine Resistance in Tuberculosis: An Evolutionary Medicine Approach

Sonnenkalb, L.; Carter, J.; Spitaleri, A.; Iqbal, Z.; Hunt, M.; Malone, K.; Utpatel, C.; Cirillo, D. m.; Rodrigues, C.; Nilgiriwala, K. S.; the CRyPTIC Consortium, ; Fowler, P. W.; Merker, M.; Niemann, S.

10.1101/2021.03.19.436148 — microbiology — Posted on 2021-03-20

1810 Life history strategies explain bacterial activity in the soil carbon cycle

Barnett, S. E.; Youngblut, N. D.; Koechli, C. N.; Buckley, D. H.

10.1101/2021.03.19.436178 — microbiology — Posted on 2021-03-20

1811 Systemic and mucosal mobilization of granulocyte subsets during lentivirus infection

Reeves, R. K.

10.1101/2021.03.19.436235 — immunology — Posted on 2021-03-20

1812 The Card19 locus of murine chromosome 13 regulates terminal cell lysis downstream of caspase activation and Gasdermin-D cleavage

10.1101/2021.03.19.436207 — immunology — Posted on 2021-03-20

1813 CCL28 modulates neutrophil responses and impacts the trajectory of mucosal infections

Perez-Lopez, A.; Silva, S.; Dillon, N.; Brandt, S.; Gerner, R.; Lee, M.; Melchior, K.; Torres-Ruiz, J.; Sosa-Hernandez, V.; Cervantes-Diaz, R.; Perez-Fragoso, A.; Romero-Ramirez, S.; Gomez-Martin, D.; Maravillas-Montero, J.; Nuccio, S.-P.; Nizet, V.; Raffatellu, M.

10.1101/2021.03.19.436197 — immunology — Posted on 2021-03-20

1814 HLA Type and Chronic Viral Infection Impact Peripheral T-cell Receptor Sharing Between Unrelated Individuals

Johnson, S. A.; Seale, S. L.; Gittelman, R. M.; Rytlewski, J. A.; Robins, H. S.; Fields, P. A.

10.1101/2021.03.19.436220 — immunology — Posted on 2021-03-20

1815 Bacterial hopanoids: a newly identified potent inducer of monocyte to macrophage differentiation

Bhattacharya, A.; Ghosh, A.; Mallik, S.; Mondal, S.; Sen, P.

10.1101/2021.03.20.436240 — cell biology — Posted on 2021-03-20

1816 Unbiased transcriptomic analysis of chondrocyte differentiation in a high-density cell culture model

Kruger, C.; Limpach, A.; Kappen, C.

10.1101/2021.03.20.436275 — developmental biology — Posted on 2021-03-20

1817 Testing the inferred transcription rates of a dynamic, gene network model in absolute units

Urquiza-Garcia, U.; Millar, A. J.

10.1101/2021.03.18.436071 — systems biology — Posted on 2021-03-20

1818 N-myristoyltransferase inhibition is synthetic lethal in MYC-deregulated cancers

Lueg, G. A.; Faronato, M.; Gorelik, A.; Goya Grocin, A.; Caamano-Gutierrez, E.; Falciani, F.; Solari, R.; Carr, R.; Bell, A. S.; Bartlett, E.; Hutton, J. A.; Llorian-Sopena, M.; Chakravarty, P.; Brzezicha, B.; Janz, M.; Garnett, M. J.; Calado, D. P.; Tate, E. W.

10.1101/2021.03.20.436222 — cancer biology — Posted on 2021-03-20

1819 Visualising formation of the ribosomal active site in mitochondria

Chandrasekaran, V.; Desai, N.; Burton, N. O.; Yang, H.; Price, J. L.; Miska, E. A.; Ramakrishnan, V.

10.1101/2021.03.19.436169 — biochemistry — Posted on 2021-03-20

1820 Nestmate recognition of early brood in ants

de Fouchier, A.; Leroy, C.; Khila, A.; d'Ettorre, P.

10.1101/2021.03.17.435807 — animal behavior and cognition — Posted on 2021-03-20

1821 Viscoelasticity and cell jamming state transition

Pajic-Lijakovic, I.; Milivojevic, M.

10.1101/2021.03.19.436195 — developmental biology — Posted on 2021-03-20

1822 Drosophila Male Accessory Gland Displays Developmental Ground Plan of a Primitive Prostate

Kumari, J.; Sinha, P.

10.1101/2021.03.20.436254 — developmental biology — Posted on 2021-03-20

1823 Talin mechanosensitivity is modulated by a direct interaction with cyclin-dependent kinase-1

Gough, R. E.; Jones, M. C.; Zacharchenko, T.; Le, S.; Yu, M.; Jacquemet, G.; muench, s. P.; Yan, J.; Humphries, J. D.; Jorgensen, C.; Humphries, M.; Goult, B. T.

10.1101/2021.03.19.436208 — cell biology — Posted on 2021-03-20

1824 Two-pore channel 2 is a key regulator of adipocyte differentiation via the cAMP signaling pathway with calpain as downstream effector

Zhang, Y.; Chan, L.-H.; Tunn, R.; Ruas, M.; Gay, D.; Todorcevic, M.; Christodoulides, C.; Parrington, J.

10.1101/2021.03.20.436264 — cell biology — Posted on 2021-03-20

1825 RIM-Binding Protein 2 organizes Ca2+ channel topography and regulates release probability and vesicle replenishment at a fast central synapse

Butola, T.; Alvanos, T.; Hintze, A.; Koppensteiner, P.; Kleindienst, D.; Wichmann, C.; Shigemoto, R.; Moser, T.

10.1101/2021.03.20.435607 — neuroscience — Posted on 2021-03-20

1826 A versatile CRISPR toolbox to study neurological CaV3.2 channelopathies by promoter-mediated transcription control

Tsortouktzidis, D.; Tröscher, A. R.; Schulz, H.; Schoch, S.; Becker, A. J.; van Loo, K. M. J.

10.1101/2021.03.20.436250 — neuroscience — Posted on 2021-03-20

1827 In silico molecular modeling and docking studies of Nano Composites compound to Regulation, inhibition and treatment leaf and stem wheat rust

Shamkh, I. M.; El Faki, A. S.; Abo El Magd, M. F.; Pratiwi, D.

10.1101/2021.03.18.436051 — bioinformatics — Posted on 2021-03-20

1828 DeepCob: Precise and high-throughput analysis of maize cob geometry using deep learning with an application in genebank phenomics

Kienbaum, L.; Correa Abondano, M.; Blas Sevillano, R. H.; Schmid, K. J.

10.1101/2021.03.16.435660 — plant biology — Posted on 2021-03-20

1829 The landscape of metabolic pathway dependencies in cancer cell lines

Joly, J. H.; Chew, B. T.; Graham, N. A.

10.1101/2020.10.05.327429 — cancer biology — Posted on 2021-03-20

1830 Cell cycle corruption in a preleukemic ETV6-RUNX1 model exposes RUNX1 addiction as a therapeutic target in acute lymphoblastic leukemia

Wray, J. P.; Deltcheva, E. M.; Boiers, C.; Richardson, S. E.; Chhetri, J. B.; Gagrica, S.; Guo, Y.; Illendula, A.; Martens, J. H.; Stunnenberg, H. H.; Bushweller, J. H.; Nimmo, R.; Enver, T.

10.1101/2020.12.22.423823 — cancer biology — Posted on 2021-03-20

1831 Direct induction of hemogenic endothelial progenitors from hPSCs by defined factors revealed by single-cell transcriptome analysis

Randolph, L. N.; Jiang, Y.; Chang, Y.; Bao, X.; Lian, X. L.

10.1101/2021.03.18.435636 — bioengineering — Posted on 2021-03-20

1832 Influence of the TorD signal peptide chaperone on Tat-dependent protein translocation

Bageshwar, U. K.; DattaGupta, A.; Musser, S. M.

10.1101/2021.03.19.436180 — biochemistry — Posted on 2021-03-20

1833 Modulation of fatty acid elongation sustains sexually dimorphic hydrocarbons and female attractiveness in Blattella germanica (L.)

Pei, X.-J.; Fan, Y.-L.; Bai, Y.; Bai, T.-T.; Schal, C.; Zhang, Z.-F.; Chen, N.; Li, S.; Liu, T.-X.

10.1101/2021.03.04.434003 — ecology — Posted on 2021-03-20

1834 TLR4-pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injury

Rosa, J. M.; Farre-Alins, V.; Ortega, M. C.; Navarrete, M.; Lopez-Rodriguez, A. B.; Palomino-Antolin, A.; Fernandez-Lopez, E.; Vila-del Sol, V.; Decouty, C.; Narros-Fernandez, P.; Clemente, D.; Egea, J.

10.1101/2020.03.01.972158 — neuroscience — Posted on 2021-03-20

1835 Gene network simulations provide testable predictions for the molecular domestication syndrome

Burban, E.; Tenaillon, M. I.; Le Rouzic, A.

10.1101/2021.03.19.436202 — evolutionary biology — Posted on 2021-03-20

1836 Specific protein-membrane interactions promote the export of metallo-β-lactamases via outer membrane vesicles

Lopez, C.; Prunotto, A.; Bahr, G.; Bonomo, R. A.; Gonzalez, L. J.; Dal Peraro, M.; Vila, A. J.

10.1101/2021.03.18.436108 — molecular biology — Posted on 2021-03-20

1837 The responsiveness of gait and balance outcomes to disease progression in Friedreich ataxia

Milne, S. C.; Kim, S. H.; Murphy, A.; Larkindale, J.; Farmer, J.; Malapira, R.; Danoudis, M.; Shaw, J.; Ramakrishnan, T.; Rasouli, F.; Yiu, E. M.; Georgiou-Karistianis, N.; Tai, G.; Zesiewicz, Z.; Delatycki, M. B.; Corben, L. A.

10.1101/2021.03.18.434657 — neuroscience — Posted on 2021-03-20

1838 Long-term patterns of an interconnected core marine microbiota

Krabberod, A. K.; Deutschmann, I. M.; Bjorbaekmo, M. F. M.; Balague, V.; Giner, C. R.; Ferrera, I.; Garces, E.; Massana, R.; Gasol, J. M.; Logares, R.

10.1101/2021.03.18.435965 — ecology — Posted on 2021-03-20

1839 Predictability of drug sensitivity in multi-species environments

Reding, C.

10.1101/2020.12.14.422780 — microbiology — Posted on 2021-03-20

1840 Genomics-informed insights into microbial degradation of N,N-dimethylformamide

Li, J.; Dijkstra, P.; Lu, Q.; Wang, S.; Chen, S.; Li, D.; Wang, Z.; Jia, Z.; Wang, L.; Shim, H.

10.1101/2021.03.18.435917 — microbiology — Posted on 2021-03-20

1841 SENP1 in the retrosplenial agranular cortex regulates core autistic-like symptoms in mice

Yang, K.; Shi, Y.; Du, X.; Zhang, Y.; Shan, S.; Yuan, Y.; Wang, R.; Zhou, C.; Liu, Y.; Cai, Z.; Wang, Y.; Fan, L.; Xu, H.; Yu, J.; Cheng, J.; Li, F.; Qiu, Z.

10.1101/2021.01.24.427868 — neuroscience — Posted on 2021-03-20

1842 Fibrinogen and Complement Factor H are promising CSF protein biomarker(s) for Parkinson's disease with cognitive impairment- A Proteomics and ELISA based study

Naskar, A.; Stezin, A.; Arpitha, D. S.; Hegde, S.; Philip, M.; Kamble, N.; Saini, J.; Yadav, Y.; Sandhya, K.; Tatu, U.; Pal, P. K.; Alladi, P. A.

10.1101/2021.03.19.436097 — neuroscience — Posted on 2021-03-20

1843 Facilitating the design of combination therapy in cancer using multipartite network models: Emphasis on acute myeloid leukemia

Jafari, M.; Mirzaie, M.; Bao, J.; Barneh, F.; Zheng, S.; Eriksson, J.; Tang, J.

10.1101/2021.03.18.436040 — systems biology — Posted on 2021-03-20

1844 Topological Tuning of DNA Mobility in Entangled Solutions of Supercoiled Plasmids

Smrek, J.; Anderson, R.; Garamella, J.; Michieletto, D.

10.1101/2020.09.21.306092 — biophysics — Posted on 2021-03-20

1845 Morphological changes in the mandibles accompany the defensive behavior of Indiana mite biting honey bees against Varroa destructor

Smith, J.; Cleare, X. L.; Given, K.; Li-Byarlay, H.

10.1101/2020.12.07.403147 — animal behavior and cognition — Posted on 2021-03-20

1846 To Group or not to group: Group size dynamics and intestinal parasites in Indian peafowl populations

Dange, P.; Mhaisalkar, P.; Paranjpe, D.

10.1101/2020.01.03.893503 — ecology — Posted on 2021-03-20

1847 Exotic bifurcations in three connected populations with Allee effect

Rost, G.; Sadeghimanesh, A.

10.1101/2021.02.03.429609 — ecology — Posted on 2021-03-20

1848 Microtubule poleward flux promotes chromosome centering on the spindle

Risteski, P.; Jagric, M.; Bozan, D.; Bosilj, A.; Pavin, N.; Tolic, I. M.

10.1101/2020.12.30.424837 — cell biology — Posted on 2021-03-20

1849 Live-cell single-molecule tracking highlights requirements for stable Smc5/6 chromatin association in vivo

Etheridge, T. J.; Villahermosa, D.; Campillo-Funollet, E.; Irmisch, A.; Watson, A. T.; Herbert, A.; Dang, H. Q.; Osborne, M. A.; Oliver, A. W.; Carr, A. M.; Murray, J. M.

10.1101/2020.06.19.148106 — molecular biology — Posted on 2021-03-20

1850 MafF is an antiviral host factor that suppresses transcription from Hepatitis B Virus core promoter

10.1101/2020.07.29.227793 — microbiology — Posted on 2021-03-20

1851 Epithelial and neutrophil interactions and coordinated response to Shigella in a human intestinal enteroid-neutrophil co-culture model

Lemme-Dumit, J. M.; Doucet, M.; Zachos, N.; Pasetti, M. F.

10.1101/2020.09.03.281535 — immunology — Posted on 2021-03-20

1852 Auditory Stimulus-response Modeling with a Match-Mismatch Task

de Cheveigne, A.; Slaney, M.; Hjortkjaer, J.; Fuglsang, S.

10.1101/2020.11.05.370072 — neuroscience — Posted on 2021-03-20

1853 Identifying disease-critical cell types and cellular processes across the human body by integration of single-cell profiles and human genetics

Jagadeesh, K. A.; Dey, K. K.; Montoro, D. T.; Gazal, S.; Engreitz, J. M.; Xavier, R. J.; Price, A. L.; Regev, A.

10.1101/2021.03.19.436212 — genomics — Posted on 2021-03-19

1854 Invariant Representation of Physical Stability in the Human Brain

Pramod, R.; Cohen, M. A.; Tenenbaum, J. B.; Kanwisher, N. G.

10.1101/2021.03.19.385641 — neuroscience — Posted on 2021-03-19

1855 Revealing the transcription factor regulatory context of human specific cortical development using single-cell multi-omics

Wu, Y.; Lake, B.; Sos, B.; Chen, S.; Duong, T. E.; Yun, Y. C.; Dong, W.; Limaye, S.; Chun, J.; Zhang, K.

10.1101/2021.03.19.436193 — genomics — Posted on 2021-03-19

1856 Exploring an experiment-split method to estimate the generalization ability in new data: DeepKme as an example

Zou, G.; Li, L.

10.1101/2021.03.19.436140 — bioinformatics — Posted on 2021-03-19

1857 Estimating the fundamental niche: accounting for the uneven availability of existing climates

Jimenez, L.; Soberon, J.

10.1101/2021.01.25.428165 — ecology — Posted on 2021-03-19

1858 DHA but not EPA induces the trans-differentiation of C2C12 cells into white-like adipocytes phenotype

Ghnaimawi, S.; Rebello, L.; Baum, J.; Huang, Y.

10.1101/2021.03.19.436137 — cell biology — Posted on 2021-03-19

1859 Insecticide resistance characteristic of Anopheles vector species successfully controlled by deployment of pyrethroid and PBO long lasting insecticidal treated nets (LLINs) in Tanzania

Matowo, J.; Weetman, D.; Pignatell, P.; Wright, A.; Charlwood, J.; Kaaya, R.; Shirima, B.; Moshi, O.; Lukole, E.; Mosha, J.; Manjurano, A.; Mosha, F.; Rowland, M.; Protopopoff, N.

10.1101/2021.03.19.436139 — molecular biology — Posted on 2021-03-19

1860 Genetic Susceptibility to Enteric Fever in Experimentally Challenged Human Volunteers

Barton, A. J.; Hill, J.; Bibi, S.; Chen, L.; Jones, C.; Jones, E.; Camara, S.; Shrestha, S.; Jin, C.; Gibani, M. M.; Dobinson, H.; Waddington, C.; Darton, T. C.; Blohmke, C. J.; Pollard, A. J.

10.1101/2021.03.19.436030 — genetics — Posted on 2021-03-19

1861 Pronounced genetic separation among varieties of the Primula cusickiana species complex, a Great Basin endemic

Koontz, A.; Pearse, W. D.; Wolf, P.

10.1101/2021.03.19.436082 — evolutionary biology — Posted on 2021-03-19

1862 Yeast proteins reversibly aggregate like amphiphilic molecules

Dasmeh, P.; Wagner, A.

10.1101/2021.03.12.435082 — molecular biology — Posted on 2021-03-19

1863 Histone H3 Clipping is a novel signature of Human Neutrophil Extracellular Traps

Tilley, D. O.; Abuabed, U.; Zimny Arndt, U.; Schmid, M.; Florian, S.; Jungblut, P. R.; Brinkmann, V.; Herzig, A.; Zychlinsky, A.

10.1101/2021.03.15.434949 — immunology — Posted on 2021-03-19

1864 Blunted Fas signaling favors RIPK1-driven neutrophil necroptosis in critically ill COVID-19 patients

Schweizer, T. A.; Mairpady Shambat, S.; Vulin, C.; Hoeller, S.; Acevedo, C.; Huemer, M.; Gomez-Mejia, A.; Chang, C.-C.; Baum, J.; Hertegonne, S.; Hitz, E.; Hofmaenner, D. A.; Buehler, P. K.; Moch, H.; Schuepbach, R. A.; Brugger, S. D.; Zinkernagel, A. S.

10.1101/2021.03.19.436166 — immunology — Posted on 2021-03-19

1865 Structure Can Predict Function in the Human Brain: A Graph Neural Network Deep Learning Model of Functional Connectivity and Centrality based on Structural Connectivity

Neudorf, J.; Kress, S.; Borowsky, R.

10.1101/2021.03.15.435531 — neuroscience — Posted on 2021-03-19

1866 How voluntary and involuntary attention differentially shape spatial resolution

Jigo, M.; Heeger, D. J.; Carrasco, M.

10.1101/2021.01.26.428173 — neuroscience — Posted on 2021-03-19

1867 Ocular pigmentation in humans, great apes, and gibbons is not suggestive of communicative functions - having an eye on the 'cooperative eye hypothesis'

Caspar, K. R.; Biggemann, M.; Geissmann, T.; Begall, S.

10.1101/2021.03.18.435993 — zoology — Posted on 2021-03-19

1868 Medium optimization for biomass production of three peat moss (Sphagnum L.) species using fractional factorial design and response surface methodology

Heck, M. A.; Melkova, I.; Posten, C.; Decker, E. L.; Reski, R.

10.1101/2021.03.19.436135 — plant biology — Posted on 2021-03-19

1869 Cell-scale biophysical determinants of cell competition in epithelia

Gradeci, D.; Bove, A.; Vallardi, G.; Lowe, A.; Banerjee, S.; Charras, G.

10.1101/729731 — biophysics — Posted on 2021-03-19

1870 Co-condensation of proteins with single- and double-stranded DNA

Renger, R.; Morin, J. A.; Lemaitre, R.; Ruer, M.; Julicher, F.; Hermann, A.; Grill, S. W.

10.1101/2021.03.17.435834 — biophysics — Posted on 2021-03-19

1871 Cryo-EM structure of an elusive pre-transport intermediate of the multidrug transporter BmrCD reveals modes of asymmetric drug binding

Thaker, T. M.; Mishra, S.; Zhou, W.; Faraldo-Gomez, J.; Mchaourab, H.; Tomasiak, T. M.

10.1101/2021.03.13.435271 — biophysics — Posted on 2021-03-19

1872 SPARC Data Structure: Rationale and Design of a FAIR Standard for Biomedical Research Data

Bandrowski, A.; Grethe, J. S.; Pilko, A.; Gillespie, T. H.; Pine, G.; Patel, B.; Surles-Zeiglera, M.; Martone, M. E.

10.1101/2021.02.10.430563 — bioinformatics — Posted on 2021-03-19

1873 CrowdGO: machine learning and semantic similarity guided consensus Gene Ontology annotation

Reijnders, M. J.; Waterhouse, R. M.

10.1101/731596 — bioinformatics — Posted on 2021-03-19

1874 Mapping single-cell atlases throughout Metazoa unravels cell type evolution

Tarashansky, A. J.; Musser, J.; Khariton, M.; Li, P.; Arendt, D.; Quake, S. R.; Wang, B.

10.1101/2020.09.28.317784 — bioinformatics — Posted on 2021-03-19

1875 Shapes and Genescapes: Mapping Multivariate Phenotype-Biological Process Associations for Craniofacial Shape

Aponte, J. D.; Katz, D. C.; Roth, D. M.; Vidal Garcia, M.; Liu, W.; Andrade, F.; Roseman, C. C.; Murray, S. A.; Cheverud, J.; Graf, D.; Marcucio, R.; Hallgrimsson, B.

10.1101/2020.11.12.378513 — genomics — Posted on 2021-03-19

1876 Substantial intraspecific variation in energy budgets: biology or artefact?

Potter, T.; Reznick, D. N.; Coulson, T.

10.1101/2021.01.07.425747 — evolutionary biology — Posted on 2021-03-19

1877 Svep1 stabilizes developmental vascular anastomosis in reduced flow conditions.

Coxam, B.; Padberg, Y.; Maier, K.; Jung, S.; Bartels-Klein, E.; Szymborska, A.; Finotto, L.; Helker, C. S. M.; Schulte-Merker, S.; Stainier, D. Y. R.; Gerhardt, H.

10.1101/2021.03.13.435246 — developmental biology — Posted on 2021-03-19

1878 Differential CTCF binding in motor neurons and lymphocytes

Atasever Arslan, B.; Brady, S. T.; Gunal Sadik, G.

10.1101/2021.03.19.435989 — developmental biology — Posted on 2021-03-19

1879 In-vivo protein nitration and de-nitration facilitate Vibrio cholerae cell survival under anaerobic condition: Consequences of Nitrite induced protein nitration

Patra, S. K.; Sinha, N.; Chakraborty, S.; Sengupta, A.; Roy, S.; Ghosh, S.

10.1101/2021.03.19.436110 — microbiology — Posted on 2021-03-19

1880 Common dandelion (Taraxacum officinale) efficiently blocks the interaction between ACE2 cell surface receptor and SARS-CoV-2 spike protein D614, mutants D614G, N501Y, K417N and E484K in vitro

Tran, H. T. T.; Le, N. P. K.; Gigl, M.; Dawid, C.; Lamy, E.

10.1101/2021.03.19.435959 — microbiology — Posted on 2021-03-19

1881 Inhibition of select actinobacteria by the organophosphate pesticide chlorpyrifos

McDonald, N. D.; Love, C. E.; Killens-Cade, R.; Werth, J. T.; Gebert, M. J.; Weber, C. F.; Nealon, C.; Sweet, C.; Fierer, N.; Gibbons, H. S.

10.1101/2021.03.18.436105 — microbiology — Posted on 2021-03-19

1882 Genomic Evidence of Environmental and Resident Salmonella Senftenberg and Montevideo Contamination in the Pistachio Supply-chain

Haendiges, J.; Davidson, G.; Pettengill, J.; Reed, E.; Blessington, T.; Miller, J. D.; Anderson, N.; Myoda, S.; Brown, E.; Zheng, J.; Tikekar, R. V.; Hoffmann, M.

10.1101/2021.03.18.436106 — microbiology — Posted on 2021-03-19

1883 Versatile genetic toolbox for Prevotella copri enables studying polysaccharide utilization systems

Li, J.; Galvez, E.; Amend, L.; Almasi, E.; Iljazovic, A.; Lesker, T.; Bielecka, A.; Strowig, T.

10.1101/2021.03.19.436125 — microbiology — Posted on 2021-03-19

1884 Anti-fibrotic activity of an antimicrobial peptide in a Drosophila model.

Khalili, D.; Kalcher, C.; Baumgartner, S.; Theopold, U.

10.1101/2021.03.19.436168 — immunology — Posted on 2021-03-19

1885 Protection induced by a human monoclonal antibody recognizing two different epitopes in a conserved region of streptococcal M proteins

Bahnan, W.; Happonen, L.; Khakzad, H.; Kumra Ahnlide, V.; de Neergaard, T.; Wrighton, S.; Bratanis, E.; Tang, D.; Hellmark, T.; Bjorck, L.; Shannon, O.; Malmstrom, L.; Malmstrom, J.; Nordenfelt, P.

10.1101/2021.03.01.433494 — immunology — Posted on 2021-03-19

1886 Does the Zebra Finch Mating Song Circuit Use Spike Times Efficiently?

Nicola, W.; Newton, T. R.; Clopath, C.

10.1101/2021.03.18.436095 — neuroscience — Posted on 2021-03-19

1887 Abi3 regulates microglial ramification and dynamic tissue surveillance in vivo.

Simonazzi, E.; Jones, R.; Chen, F.; Ranson, A.; Stevenson-Hoare, J.; Escott-Price, V.; Sengpiel, F.; Morgan, B. P.; Taylor, P. R.

10.1101/2021.03.19.436147 — neuroscience — Posted on 2021-03-19

1888 B-SOiD: An Open Source Unsupervised Algorithm for Discovery of Spontaneous Behaviors

Hsu, A. I.; Yttri, E. A.

10.1101/770271 — neuroscience — Posted on 2021-03-19

1889 Validating the automation of different measures of high temperature tolerance of small terrestrial insects

MacLean, H. J.; Hansen, J. H.; Sorensen, J. G.

10.1101/2021.03.19.436121 — physiology — Posted on 2021-03-19

1890 Variations in phenolic levels in grapevine buds at eco-dormancy after chemically-induced stress conditions

Daskalakis, I.; Stavrakaki, M.; Sotirakoglou, K.; Biniari, K.

10.1101/2021.03.19.436201 — biochemistry — Posted on 2021-03-19

1891 Identification and assessment of cardiolipin interactions with E. coli inner membrane proteins

Corey, R. A.; Song, W.; Duncan, A.; Ansell, T. B.; Sansom, M. S. P.; Stansfeld, P. J.

10.1101/2021.03.19.436130 — biochemistry — Posted on 2021-03-19

1892 Deficiency of MicroRNA-181a Results in Transcriptome-Wide Cell Specific Changes in the Kidney that Lead to Elevated Blood Pressure and Salt Sensitivity

Paterson, M. R.; Jackson, K. L.; Dona, M. I.; Farrugia, G. E.; Visniauskas, B.; Watson, A. M.; Johnson, C.; Prieto, M. C.; Evans, R. E.; Charchar, F.; Pinto, A. R.; Marques, F. Z.; Head, G. A.

10.1101/2021.03.18.436092 — genomics — Posted on 2021-03-19

1893 Sex-specific transcript diversity is regulated by a maternal pioneer factor in early Drosophila embryos

Ray, M.; Conard, A. M.; Urban, J.; Larschan, E.

10.1101/2021.03.18.436074 — genomics — Posted on 2021-03-19

1894 Joint effects of genes underlying a temperature specialization tradeoff in yeast

AlZaben, F.; Chuong, J. N.; Abrams, M. B.; Brem, R. B.

10.1101/2021.03.18.436093 — evolutionary biology — Posted on 2021-03-19

1895 Diet-induced changes in titer support a threshold effect of Wolbachia-associated plastic recombination in Drosophila melanogaster

Mostoufi, S. L.; Singh, N. D.

10.1101/2021.03.18.436076 — evolutionary biology — Posted on 2021-03-19

1896 Rats in the city: implications for zoonotic disease risk in an urbanizing world

Blasdell, K. R.; Morand, S.; Laurance, S. G. W.; Doggett, S. L.; Hahs, A.; Perera, D.; Firth, C.

10.1101/2021.03.18.436089 — ecology — Posted on 2021-03-19

1897 Long-Term Imaging of Living Adult Zebrafish

Castranova, D.; Samasa, B.; Venero Galanternik, M.; Gore, A.; Weinstein, B. M.

10.1101/2021.03.19.436170 — developmental biology — Posted on 2021-03-19

1898 Aniridia-related Keratopathy Relevant Cell Signaling Pathways in Human Fetal Corneas

Sloniecka, M.; Vicente, A.; Bystrom, B.; Liu, J.; Pedrosa-Domellof, F.

10.1101/2021.03.19.436141 — developmental biology — Posted on 2021-03-19

1899 The inhibitory effects of toothpaste and mouthwash ingredients on the interaction between the SARS-CoV-2 spike protein and ACE2, and the protease activity of TMPRSS2, in vitro

Tateyama-Makino, R.; Abe-Yutori, M.; Iwamoto, T.; Tsutsumi, K.; Tsuji, M.; Morishita, S.; Kurita, K.; Yamamoto, Y.; Nishinaga, E.; Tsukinoki, K.

10.1101/2021.03.19.435740 — molecular biology — Posted on 2021-03-19

1900 Systematic in vivo quantification of microRNA affinities

Brosig, S.; Sladitschek, H. L.; Neveu, P. A.

10.1101/2021.03.19.436154 — molecular biology — Posted on 2021-03-19

1901 Combined computational and cellular screening identifies synergistic inhibition of SARS-CoV-2 by lenvatinib and remdesivir

Pohl, M. O.; Busnadiego, I.; Marrafino, F.; Wiedmer, L.; Hunziker, A.; Fernbach, S.; Omori, E.; Hale, B. G.; Caflisch, A.; Silke, S.

10.1101/2021.03.19.435806 — microbiology — Posted on 2021-03-19

1902 Phycobilisome breakdown effector NblD is required to maintain the cellular amino acid composition during nitrogen starvation

Krauspe, V.; Timm, S.; Hageman, M.; Hess, W.

10.1101/2021.03.18.436103 — microbiology — Posted on 2021-03-19

1903 Multiomics Interrogation into HBV (Hepatitis B Virus)-Host Interaction Reveals Novel Coding potential in Human Genome, and Identifies Canonical and Non-canonical Proteins as Host Restriction Factors against HBV

Yuan, S.; Liao, G.; Zhang, M.; Zhu, Y.; Xiao, W.; Wang, K.; Jia, C.; Deng, Q.; Zhang, J.; Xu, P.; Hu, R. C.

10.1101/2021.03.19.436126 — microbiology — Posted on 2021-03-19

1904 Autophosphorylation of the KaiC-like protein ArlH inhibits oligomerisation and interaction with ArlI, the motor ATPase of the archaellum

de Sousa Machado, J. N.; Vollmar, L.; Schimpf, J.; Chaudhury, P.; Kumariya, R.; der Does, C. v.; Hugel, T.; Albers, S.-V.

10.1101/2021.03.19.436134 — microbiology — Posted on 2021-03-19

1905 Reduced neutralization of SARS-CoV-2 variants by convalescent plasma and hyperimmune intravenous immunoglobulins for treatment of COVID-19

Tang, J.; Lee, Y.; Ravichandran, S.; Grubbs, G.; Huang, C.; Stauft, C.; Wang, T.; Golding, B.; Golding, H.; Khurana, S.

10.1101/2021.03.19.436183 — immunology — Posted on 2021-03-19

1906 Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection

Perez-Gomez, A.; Vitalle, J.; Gasca-Capote, M. d. C.; Gutierrez-Valencia, A.; Trujillo-Rodriguez, M.; Serna-Gallego, A.; Munoz-Muela, E.; Jimenez-Leon, M. d. l. R.; Rafii-El-Idrissi Benhnia, M.; Rivas-Jeremias, I.; Sotomayor, C.; Roca-Oporto, C.; Espinosa, N.; Infante-Dominguez, C.; Crespo-Rivas, J. C.; Fernandez-Villar, A.; Perez-Gonzalez, A.; Lopez-Cortes, L. F.; Poveda, E.; Ruiz-Mateos, E.

10.1101/2021.03.18.436001 — immunology — Posted on 2021-03-19

1907 Two subsets of human marginal zone B cells resolved by global analysis of lymphoid tissues and blood

Siu, J. H.; Pitcher, M. J.; Tull, T. J.; Guesdon, W.; Montorsi, L.; Armitage, C.; Mahbubani, K. T.; Ellis, R.; Dhami, P.; Todd, K.; Kadolsky, U. D.; Kleeman, M.; D'Cruz, D. P.; Saeb-Parsy, K.; Bemark, M.; Pettigrew, G. J.; Spencer, J.

10.1101/2021.03.19.436131 — immunology — Posted on 2021-03-19

1908 Loss-of-function variants in the cardiac Kv11.1 channel as a genetic biomarker for SUDEP

Soh, M. S.; .Bagnall, R. D.; Bennett, M. F.; Bleakley, L. E.; Mohamed Syazwan, E. S.; Phillips, A. M.; Chiam, M. D. F.; McKenzie, C. E.; Hildebrand, M.; Crompton, D.; Bahlo, M.; Semsarian, C.; Scheffer, I. E.; Berkovic, S. F.; Reid, C. A.

10.1101/2021.03.19.436102 — neuroscience — Posted on 2021-03-19

1909 Parthanatos-inducing zinc agent C010DS-Zn elicits anti-tumor immune responses involving T cells and macrophages in vivo

Chung, J. F.; Her, Z.; Kong, W. M.; Chen, Q.

10.1101/2021.03.18.433812 — pharmacology and toxicology — Posted on 2021-03-19

1910 Direct induction of hemogenic endothelial progenitors from hPSCs by defined factors revealed by single-cell transcriptome analysis

Randolph, L. N.; Jiang, Y.; Chang, Y.; Bao, X.; Lian, X. L.

10.1101/2021.03.18.435636 — bioengineering — Posted on 2021-03-19

1911 Antibody evasion by the Brazilian P.1 strain of SARS-CoV-2

Dejnirattisai, W. -; Zhou, D. -; Supasa, P. -; Liu, C. -; Mentzer, A. J.; Ginn, H. M.; Zhao, Y. -; Duyvesteyn, H. M. E.; Tuekprakhon, A.; Nutalai, R.; Wang, B. -; Paesen, G. C.; Lopez-Camacho, C. -; Slon-Campos, J. -; Walter, T.; Skelly, D.; Clemens, S. A. C.; Naveca, F. G.; Nascimento, V. -; Nascimento, F. -; da Costa, C. F.; Resende, P. C.; Pauvolid-Correa, A.; Siqueira, M. M.; Dold, C.; Levin, R. -; Dong, T. -; Pollard, A. J.; Knight, J. C.; Crook, D.; Lambe, T.; Clutterbuck, E.; Bibi, S.; Flaxman, A.; Bittaye, M.; Belij-rammerstorfer, S.; Gilbert, S.; Carroll, M. W.; Klenerman, P. -; Barne

10.1101/2021.03.12.435194 — microbiology — Posted on 2021-03-19

1912 ODOR IDENTITY CAN BE EXTRACTED FROM THE RECIPROCAL CONNECTIVITY BETWEEN OLFACTORY BULB AND PIRIFORM CORTEX IN HUMANS

Iravani, B.; Arshamian, A.; Lundqvist, M.; Kay, L. M.; Wilson, D. A.; Lundstrom, J. N.

10.1101/2021.03.18.436041 — neuroscience — Posted on 2021-03-19

1913 Insights into single hiPSC-derived cardiomyocyte phenotypes and maturation using ConTraX, an efficient pipeline for tracking contractile dynamics

Pardon, G.; Lewis, H.; Vander Roest, A. S.; Castillo, E. A.; Wilson, R. E.; Denisin, A. K.; Blair, C. A.; Birnbaum, F.; Holbrook, C.; Koleckar, K.; Chang, A. C.-Y.; Blau, H. M.; Pruitt, B.

10.1101/2021.03.18.436014 — bioengineering — Posted on 2021-03-19

1914 Genomic taxonomic assignment of individual root-knot nematodes

Sellers, G. S.; Jeffares, D. C.; Lawson, B.; Prior, T.; Lunt, D. H.

10.1101/2021.03.18.435936 — genomics — Posted on 2021-03-19

1915 scDALI: Modelling allelic heterogeneity of DNA accessibility in single-cells reveals context-specific genetic regulation

Heinen, T.; Secchia, S.; Reddington, J. P.; Zhao, B.; Furlong, E. E. M.; Stegle, O.

10.1101/2021.03.19.436142 — genomics — Posted on 2021-03-19

1916 Exploitation of the genetic variability in the genotype of Egyptian Wheat by studding Molecular Markers, Molecular Docking, and Nano Composites. Regulation of leaf and stem rust.

Shamkh, I. M.; El Faki, A. S.; Abo El Magd, M. F.; Pratiwi, D.

10.1101/2021.03.18.436051 — genetics — Posted on 2021-03-19

1917 Understanding and predicting socioeconomic determinants of deforestation in Vietnam's Central Annamites Landscape (CAL): Pilot study implementing a spatial econometric approach

Bernhard, K. P.; Zenobi, S.; Shapiro, A. C.

10.1101/2021.03.18.436032 — ecology — Posted on 2021-03-19

1918 A novel SARS-CoV-2 related virus with complex recombination isolated from bats in Yunnan province, China

Li, L.; Wang, J.; Ma, X.; Li, J.; Yang, X.; Shi, W.; Duan, Z.

10.1101/2021.03.17.435823 — microbiology — Posted on 2021-03-19

1919 Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states

Triana, S. H.; Vonficht, D.; Jopp-Saile, L.; Raffel, S.; Lutz, R.; Leonce, D. R.; Ordonez-Rueda, D.; Ramasz, B.; Boch, T.; Jann, J.-C.; Nowak, D.; Hofmann, W.-K.; Muller-Tidow, C.; Huebschmann, D.; Alexandrov, T.; Benes, V.; Trumpp, A.; Paulsen, M.; Velten, L.; Haas, S.

10.1101/2021.03.18.435922 — immunology — Posted on 2021-03-19

1920 Chromatin architecture in addiction circuitry elucidates biological mechanisms underlying cigarette smoking and alcohol use traits.

Sey, N. Y. A.; Hu, B.; Iskhakova, M.; Sun, H.; Shokrian, N.; Hutta, G.; Marks, J.; Quach, B. C.; Johnson, E. O.; Hancock, D. B.; Akbarian, S.; Won, H.

10.1101/2021.03.18.436046 — neuroscience — Posted on 2021-03-19

1921 Exploration-based learning of a step to step controller predicts locomotor adaptation

Seethapathi, N.; Clark, B.; Srinivasan, M.

10.1101/2021.03.18.435986 — neuroscience — Posted on 2021-03-19

1922 Focal seizures are organized by feedback between neural activity and ion concentration changes

Gentiletti, D.; de Curtis, M.; Gnatkovsky, V.; Suffczynski, P.

10.1101/2021.03.18.435995 — neuroscience — Posted on 2021-03-19

1923 Facilitating the design of combination therapy in cancer using multipartite network models: Emphasis on acute myeloid leukemia

Jafari, M.; Mirzaie, M.; Bao, J.; Barneh, F.; Zheng, S.; Eriksson, J.; Tang, J.

10.1101/2021.03.18.436040 — systems biology — Posted on 2021-03-19

1924 Correlation analysis of target selectivity and side effects of FDA-approved kinase inhibitors

Bayazeid, O.; Rahman, T.

10.1101/2021.03.18.435943 — pharmacology and toxicology — Posted on 2021-03-19

1925 Structure and dynamics of the SARS-CoV-2 envelope protein monomer

Kuzmin, A.; Orekhov, P.; Astashkin, R.; Gordeliy, V.; Gushchin, I.

10.1101/2021.03.10.434722 — biophysics — Posted on 2021-03-19

1926 RENET2: High-Performance Full-text Gene-Disease Relation Extraction with Iterative Training Data Expansion

Su, J.; Wu, Y.; Ting, H.-F.; Lam, T.-W.; Luo, R.

10.1101/2021.03.18.436005 — bioinformatics — Posted on 2021-03-19

1927 CONSULT: Accurate contamination removal using locality-sensitive hashing

Rachtman, E.; Bafna, V.; Mirarab, S.

10.1101/2021.03.18.436035 — bioinformatics — Posted on 2021-03-19

1928 A Mendelian randomization study of glycemic and anthropometric traits and Parkinson's disease

Grover, S.; Graf, R.; Klein, C.; Brueggemann, N.; Koenig, I. R.; Greco M, F. D.; Sharma, M.

10.1101/2020.03.31.017566 — genetics — Posted on 2021-03-19

1929 Identification of a Major Locus for Flowering Pattern Sheds Light on Plant Architecture Diversification in Cultivated Peanut

Kunta, S.; Chu, Y.; Levy, Y.; Harel, A.; Abbo, S.; Ozias-Akins, P.; Hovav, R.

10.1101/2021.03.18.435916 — genetics — Posted on 2021-03-19

1930 On the genetic architecture of rapidly adapting and convergent life history traits in guppies

Whiting, J. R.; Paris, J. R.; Parsons, P. J.; Matthews, S.; Reynoso, Y.; Hughes, K. A.; Reznick, D.; Fraser, B. A.

10.1101/2021.03.18.435980 — evolutionary biology — Posted on 2021-03-19

1931 Ignoring errors causes inaccurate timing of single-cell phylogenies

Chen, K.; Welch, D.; Drummond, A. J.

10.1101/2021.03.17.435906 — evolutionary biology — Posted on 2021-03-19

1932 Differential responses of amphibians and reptiles to land-use change in the biodiversity hotspot of north-eastern Madagascar

Fulgence, T. R.; Martin, D. A.; Randriamanantena, R.; Botra, R.; Befidimanana, E.; Osen, K.; Wurz, A.; Kreft, H.; Andrianarimisa, A.; Ratsoavina, F. M.

10.1101/2021.03.18.435920 — ecology — Posted on 2021-03-19

1933 Agricultural pressures impair trophic link between aquatic microorganisms and invertebrates

Blom, R.; Barmentlo, H.; Schrama, M.; Hunting, E.

10.1101/2021.03.18.435985 — ecology — Posted on 2021-03-19

1934 Transcriptomic analysis of temporal shifts in berry development between two grapevine cultivars of the Pinot family reveals potential ripening-regulative genes

Theine, J.; Holtgräwe, D.; Herzog, K.; Schwander, F.; Kicherer, A.; Hausmann, L.; Viehöver, P.; Töpfer, R.; Weisshaar, B.

10.1101/2021.03.18.436038 — developmental biology — Posted on 2021-03-19

1935 Defective NET Clearance contributes to sustained FXII Activation in COVID-19-associated Pulmonary Thrombo-Inflammation

Englert, H.; Rangaswamy, C.; Deppermann, C.; Sperhake, J.-P.; Krisp, C.; Schreier, D.; Gordon, E.; Konrath, S.; Haddad, M.; Pula, G.; Mailer, R.; Schlueter, H.; Kluge, S.; Langer, F.; Pueschel, K.; Panousis, K.; Stavrou, E.; Maas, C.; Renne, T.; Frye, M.

10.1101/2020.12.29.424644 — molecular biology — Posted on 2021-03-19

1936 Manipulation of the unfolded protein response: a pharmacological strategy against coronavirus infection

Echavarria-Consuegra, L.; Cook, G. M.; Busnadiego, I.; Lefevre, C.; Keep, S.; Brown, K.; Doyle, N.; Dowgier, G.; Franaszek, K.; Moore, N. A.; Siddell, S. G.; Bickerton, E.; Hale, B. G.; Firth, A. E.; Brierley, I.; Irigoyen, N.

10.1101/292979 — microbiology — Posted on 2021-03-19

1937 Drosophila antimicrobial peptides and lysozymes regulate gut microbiota composition and abundance

Marra, A.; Hanson, M. A.; Kondo, S.; Erkosar, B.; Lemaitre, B.

10.1101/2021.03.19.436153 — microbiology — Posted on 2021-03-19

1938 P2X7 receptor signaling is not required but can enhance Th17 differentiation.

Yang, Y.; Killeen, M. E.; Sumpter, T. L.; Mathers, A. R.

10.1101/2021.03.19.435855 — immunology — Posted on 2021-03-19

1939 TCR meta-clonotypes for biomarker discovery with tcrdist3: identification of public, HLA-restricted SARS-CoV-2 associated TCR features

Mayer-Blackwell, K.; Schattgen, S.; Cohen-Lavi, L.; Crawford, J. C.; Souquette, A.; Gaevert, J. A.; Hertz, T.; Thomas, P. G.; Bradley, P.; Fiore-Gartland, A.

10.1101/2020.12.24.424260 — immunology — Posted on 2021-03-19

1940 An fMRI-based brain marker predicts individual differences in delay discounting

Koban, L.; Lee, S.; Schelski, D. S.; Simon, M.-C.; Lerman, C.; Weber, B.; Kable, J. W.; Plassmann, H.

10.1101/2021.03.18.435969 — neuroscience — Posted on 2021-03-19

1941 EMBED: a low dimensional reconstruction of gut microbiome dynamics based on ecological normal modes

Shahin, M.; Ji, B. W.; Dixit, P. D.

10.1101/2021.03.18.436036 — systems biology — Posted on 2021-03-19

1942 Closed-Loop Control between Two GTPase Switches makes the Secretory Functions of the Golgi Responsive to Growth Factors

Qiao, L.; Lo, I.-C.; Midde, K.; Aznar, N.; Abd El-Hafeez, A. A.; Lopez-Sanchez, I.; Gupta, V.; Farquhar, M.; Rangamani, P.; Ghosh, P.

10.1101/2021.03.18.436048 — systems biology — Posted on 2021-03-19

1943 Discovery of a Novel Non-Narcotic Analgesic Derived from the CL-20 Explosive: Synthesis, Pharmacology and Target Identification of Thio-wurtzine, a Potent Inhibitor of the Opioid Receptors and the Voltage-Dependent Calcium Channels

Aguero, S.; Megy, S.; Terreux, R.; Fournier, M.; Kulagina, D.; Sysolyatin, S.; Kalashnikov, A.; Krylova, S.; Vorozhtsov, A.; Zhdanov, V.

10.1101/2021.03.18.435981 — pharmacology and toxicology — Posted on 2021-03-19

1944 BATL: Bayesian annotations for targeted lipidomics

Chitpin, J. G.; Taylor, G. P.; Xu, H.; Nguyen, T. T.; Ortega, R.; Tomlinson, J. J.; Schlossmacher, M. G.; Saunders-Pullman, R.; Bennett, S. A. L.; Perkins, T. J.

10.1101/2021.03.18.435788 — bioinformatics — Posted on 2021-03-19

1945 Comparative genomics reveals evolutionary drivers of sessile life and left-right shell asymmetry in bivalves

Zhang, Y.; Mao, F.; Xiao, S.; Yu, H.; Xiang, Z.; Xu, F.; Li, J.; Wang, L.; Xiong, Y.; Chen, M.; Bao, Y.; Deng, Y.; Huo, Q.; Zhang, L.; Liu, W.; Li, X.; Ma, H.; Zhang, Y.; Mu, X.; Liu, M.; Zheng, H.; Wong, N.-K.; Yu, Z.

10.1101/2021.03.18.435778 — genomics — Posted on 2021-03-19

1946 Cross-platform proteomics to advance genetic prioritisation strategies

Pietzner, M.; Wheeler, E.; Carrasco-Zanini, J.; Kerrison, N. D.; Oerton, E.; Koprulu, M.; Luan, J.; Hingorani, A. D.; Williams, S. A.; Wareham, N. J.; Langenberg, C.

10.1101/2021.03.18.435919 — genetics — Posted on 2021-03-19

1947 A two-type branching process model of gene family evolution

Zwaenepoel, A.; Van de Peer, Y.

10.1101/2021.03.18.435925 — evolutionary biology — Posted on 2021-03-19

1948 Evolutionary determinants of non-seasonal breeding in wild chacma baboons

Dezeure, J.; Baniel, A.; Burtschell, L.; Carter, A.; Godelle, B.; Cowlishaw, G.; Huchard, E.

10.1101/2021.03.18.435953 — evolutionary biology — Posted on 2021-03-19

1949 Long-term patterns of an interconnected core marine microbiota

Krabberod, A. K.; Deutschmann, I. M.; Bjorbaekmo, M. F. M.; Balague, V.; Giner, C. R.; Ferrera, I.; Garces, E.; Massana, R.; Gasol, J. M.; Logares, R.

10.1101/2021.03.18.435965 — ecology — Posted on 2021-03-19

1950 Buried but unsafe - defoliation depletes the underground storage organ (USO) of the mesic grassland geophyte, Hypoxis hemerocallidea

Morris, C.

10.1101/2021.03.18.435941 — ecology — Posted on 2021-03-19

1951 Natal and adult dispersal among four elephant seal colonies

Zeno, R.; Condit, R.; Allen, S. G.; Duncan, G.

10.1101/2021.03.18.435977 — ecology — Posted on 2021-03-19

1952 Rhythmic Accessibility to Sequential Working Memory in a Theta Phase-Dependent Manner

Ideriha, T.; Ushiyama, J.

10.1101/2021.03.18.435754 — neuroscience — Posted on 2021-03-19

1953 Cross-Species Experiments Reveal Widespread Cochlear Neural Damage in Normal Hearing

Bharadwaj, H. M.; Hustedt-Mai, A. R.; Ginsberg, H. M.; Dougherty, K. M.; Muthaiah, V. P. K.; Hagedorn, A.; Simpson, J. M.; Heinz, M. G.

10.1101/2021.03.17.435900 — neuroscience — Posted on 2021-03-19

1954 Patterns of brain asymmetry associated with polygenic risks for autism and schizophrenia implicate language and executive functions but not brain masculinization

Sha, Z.; Schijven, D.; Francks, C.

10.1101/2021.03.19.436120 — neuroscience — Posted on 2021-03-19

1955 Fiber tractography bundle segmentation depends on scanner effects, acquisition, diffusion sensitization, and bundle segmentation workflow

Schilling, K.; Tax, C. M. W.; Rheault, F.; Hansen, C. B.; Yang, Q.; Yeh, F.-c.; Cai, L. Y.; Anderson, A. W.; Landman, B. A.

10.1101/2021.03.17.435872 — neuroscience — Posted on 2021-03-19

1956 Ocular pigmentation in humans, great apes, and gibbons is not suggestive of communicative functions - having an eye on the 'cooperative eye hypothesis'

Caspar, K. R.; Biggemann, M.; Geissmann, T.; Begall, S.

10.1101/2021.03.18.435993 — zoology — Posted on 2021-03-19

1957 Transcriptional condensates formed by phase-separated ALOG family proteins control flowering and inflorescence architecture in tomato

XU, C.; Huang, X.; Xiao, N.; Xie, Y.; Tang, L.; Zhang, Y.; Yu, Y.

10.1101/2021.03.18.435998 — plant biology — Posted on 2021-03-19

1958 Predicting tomato field-yield using continuous monitoring of young tomato water status

Gosa, S.; Koch, A.; Shenhar, I.; Hirschberg, J.; Zamir, D.; Moshelion, M.

10.1101/2021.03.18.435447 — physiology — Posted on 2021-03-19

1959 Bimodal fibrosis in a novel mouse model of bleomycin-induced usual interstitial pneumonia

Miura, Y.; Lam, M.; Bourke, J. E.; KANAZAWA, S.

10.1101/2021.03.18.435059 — pathology — Posted on 2021-03-19

1960 Portable framework to deploy deep learning segmentation models for medical images

Iyer, A.; Locastro, E.; Apte, A.; Veeraraghavan, H.; Deasy, J. O.

10.1101/2021.03.17.435903 — bioinformatics — Posted on 2021-03-19

1961 Kawasaki Disease patient stratification and pathway analysis based on host transcriptomic and proteomic profiles

Jackson, H.; Menikou, S.; Hamilton, S.; McArdle, A.; Shimizu, C.; Galassini, R.; Huang, H.; Kim, J.; Tremoulet, A.; de Jonge, M.; Kuijpers, T. W.; Wright, V.; Burns, J.; Casals-Pascual, C.; Herberg, J.; Levin, M.; Kaforou, M.; The PERFORM Consortium,

10.1101/2021.03.18.435948 — bioinformatics — Posted on 2021-03-19

1962 A Deep Learning Model for Molecular Label Transfer that Enables Cancer Cell Identification from Histopathology Images

Su, A.; Lee, H.; Tan, X.; Suarez, C. J.; Andor, N.; Nguyen, Q.; Ji, H.

10.1101/2021.03.18.436004 — bioinformatics — Posted on 2021-03-19

1963 Predicting continuous ground reaction forces from accelerometers during uphill and downhill running: A recurrent neural network solution

Alcantara, R. S.; Edwards, W. B.; Millet, G. Y.; Grabowski, A. M.

10.1101/2021.03.17.435901 — bioengineering — Posted on 2021-03-19

1964 Sponges are highly resistant to radiation exposure and cancer

Fortunato, A.; Taylor, J.; Scirone, J.; Aktipis, A.; Maley, C.

10.1101/2021.03.17.435910 — evolutionary biology — Posted on 2021-03-19

1965 Limited effects of m6A modification on mRNA partitioning into stress granules

Khong, A.; Matheny, T.; Huynh, T. N.; Babl, V.; Parker, R.

10.1101/2021.03.19.436090 — molecular biology — Posted on 2021-03-19

1966 Style Transfer Using Generative Adversarial Networks for Multi-Site MRI Harmonization

Liu, M.; Maiti, P.; Thomopoulos, S. I.; Zhu, A.; Chai, Y.; Kim, H.; Jahanshad, N.

10.1101/2021.03.17.435892 — neuroscience — Posted on 2021-03-19

1967 A new drug candidate for glycogen storage disorders enhances glycogen catabolism: Lessons from Adult Polyglucosan Body Disease models

Vaknin, H.; Mishra, K.; D'Souza, J.; Marisat, M.; Sprecher, U.; Wald-Altman, S.; Dukhovny, A.; Raviv, Y.; Da'adoosh, B.; Engel, H.; Benhamron, S.; Nitzan, K.; Permyakova, A.; Rosenmann, H.; Lossos, A.; Tam, J.; Minassian, B. A.; Kakhlon, O.; Weil, M.

10.1101/2021.03.18.436069 — neuroscience — Posted on 2021-03-19

1968 Fibrinogen and Complement Factor H are promising CSF protein biomarker(s) for Parkinson's disease with cognitive impairment- A Proteomics and ELISA based study

Naskar, A.; Stezin, A.; Arpitha, D. S.; Hegde, S.; Philip, M.; Kamble, N.; Saini, J.; Yadav, Y.; Sandhya, K.; Tatu, U.; Pal, P. K.; Alladi, P. A.

10.1101/2021.03.19.436097 — neuroscience — Posted on 2021-03-19

1969 Predicting intelligence from fMRI data of the human brain in a few minutes of scan time

Lohmann, G.; Lacosse, E.; Ethofer, T.; Kumar, V. J.; Scheffler, K.; Jost, J.

10.1101/2021.03.18.435935 — neuroscience — Posted on 2021-03-19

1970 CHRONIC INFLAMMATION IN ULCERATIVE COLITIS CAUSES LONG TERM CHANGES IN GOBLETCELL FUNCTION

Singh, V.; Johnson, K.; Yin, J.; Lee, S.; Lin, R.-X.; Yu, H.; In, J.; Abel, J. F.; Zachos, N.

10.1101/2021.03.17.435871 — physiology — Posted on 2021-03-19

1971 Spectracular: minimizing spectral overlap in multicolor flow cytometry experiments

Barnkob, M. B.; Benso, A.; Politano, G.; Olsen, L. R.

10.1101/2021.03.17.435861 — bioinformatics — Posted on 2021-03-19

1972 A structural property for reduction of biochemical networks

Kueken, A.; Wendering, P.; Langary, D.; Nikoloski, Z.

10.1101/2021.03.17.435785 — bioinformatics — Posted on 2021-03-19

1973 Assigning confidence to structural annotations from mass spectra with COSMIC

Hoffmann, M. A.; Nothias, L.-F.; Ludwig, M.; Fleischauer, M.; Gentry, E. C.; Witting, M.; Dorrestein, P. C.; Dührkop, K.; Böcker, S.

10.1101/2021.03.18.435634 — bioinformatics — Posted on 2021-03-19

1974 SCAPTURE: a deep learning-embedded pipeline that captures polyadenylation information from 3' tag-based RNA-seq of single cells

Li, G.-W.; Nan, F.; Yuan, G.-H.; Tian, B.; Yang, L.

10.1101/2021.03.17.435782 — bioinformatics — Posted on 2021-03-19

1975 Nanoparticle Cellular Internalization is Not Required for RNA Delivery to Mature Plant Leaves

Zhang, H.; Goh, N. S.; Wang, J.; Demirer, G. S.; Butrus, S.; Park, S.-J.; Landry, M. P.

10.1101/2021.03.17.435888 — bioengineering — Posted on 2021-03-19

1976 Fast and accurate genome-wide predictions and structural modeling of protein-protein interactions using Galaxy

Guerler, A.; Baker, D.; van den Beek, M.; Bouvier, D.; Coraor, N.; Schatz, M. C.; Nekrutenko, A.

10.1101/2021.03.17.435706 — genomics — Posted on 2021-03-19

1977 Genomic and Chemical Diversity of Commercially Available Industrial Hemp Accessions

Johnson, M. S.; Wallace, J. G.

10.1101/2021.03.17.435786 — genomics — Posted on 2021-03-19

1978 Pooled Single-Molecule transcriptomics identifies a giant gene under balancing selection in sunflower

BADOUIN, H.; Boniface, M.-C.; Pouilly, N.; Fuchs, A.-L.; Vear, F.; Langlade, N. B.; Gouzy, J.; Munos, S.

10.1101/2021.03.17.435796 — evolutionary biology — Posted on 2021-03-19

1979 Exclusion of the fittest predicts microbial community diversity in fluctuating environments

Shibasaki, S.; Mobilia, M.; Mitri, S.

10.1101/2020.07.22.216010 — ecology — Posted on 2021-03-19

1980 Distance decay 2.0 - a global synthesis of taxonomic and functional turnover in ecological communities.

Graco-Roza, C.; Aarnio, S.; Abrego, N.; Acosta, A. T. R.; Alahuhta, J.; Altman, J.; Angiolini, C.; Aroviita, J.; Attorre, F.; Baastrup-Spohr, L.; Barrera-Alba, J. J.; Belmaker, J.; Biurrun, I.; Bonari, G.; Bruelheide, H.; Burrascano, S.; Carboni, M.; Cardoso, P.; Carvalho, J. C.; Castaldelli, G.; Christensen, M.; Correa, G.; Dembicz, I.; Dengler, J.; Dolezal, J.; Domingos, P.; Eros, T.; Ferreira, C. E. L.; Filibeck, G.; Floeter, S. R.; Friedlander, A.; Gammal, J.; Gavioli, A.; Gossner, M. M.; Granot, I.; Guarino, R.; Gustafsson, C.; Hayden, B.; He, S.; Heilmann-Clausen, J.; Heino, J.; Hunter,

10.1101/2021.03.17.435827 — ecology — Posted on 2021-03-19

1981 Optimizing smartphone-based canopy hemispherical photography

Diaz, G. M.

10.1101/2021.03.17.435793 — ecology — Posted on 2021-03-19

1982 Environmental persistence but not per capita transmission rates of a chytrid fungus determines infection prevalence

Rumschlag, S. L.; Roth, S. A.; McMahon, T. A.; Rohr, J. R.; Civitello, D. J.

10.1101/2021.03.17.435818 — ecology — Posted on 2021-03-19

1983 Mechanical bistability enabled by ectodermal compression facilitates Drosophila mesoderm invagination

Guo, H.; Swan, M.; Huang, S.; He, B.

10.1101/2021.03.18.435928 — developmental biology — Posted on 2021-03-19

1984 Dopamine and reward-related vigor in younger and older human participants

Hird, E. J.; Beierholm, U.; De Boer, L.; Axelsson, J.; Riklund, K.; Nyberg, L.; Beckman, L.; Guitart-Masip, M.

10.1101/2021.03.17.435869 — neuroscience — Posted on 2021-03-19

1985 The long-time orphan protist Meringosphaera mediterranea Lohmann, 1902 is a centrohelid heliozoan

Zlatogursky, V.; Shɨshkin, Y.; Drachko, D.; Burki, F.

10.1101/2021.03.17.435794 — zoology — Posted on 2021-03-19

1986 Scaling down the microbial loop: data-driven modelling of growth interactions in a diatom-bacterium co-culture

Daly, G.; Perrin, E.; Viti, C.; Fondi, M.; Adessi, A.

10.1101/2021.03.17.435777 — systems biology — Posted on 2021-03-19

1987 Using machine learning and big data to explore the drug resistance landscape in HIV

Blassel, L.; Tostevin, A.; Villabona-Arenas, C. J.; Peeters, M.; Hue, S.; Gascuel, O.

10.1101/2021.03.15.435398 — bioinformatics — Posted on 2021-03-19

1988 Molecular basis for two stereoselective Diels-Alderases that produce decalin skeletons

Fujiyama, K.; Kato, N.; Re, S.; Kinugasa, K.; Watanabe, K.; Takita, R.; Nogawa, T.; Hino, T.; Osada, H.; Sugita, Y.; Takahashi, S.; Nagano, S.

10.1101/2021.02.01.429105 — biochemistry — Posted on 2021-03-19

1989 Mechanically Sensitive HSF1 is a Key Regulator of Left-Right Symmetry Breaking in Zebrafish Embryos

Du, J.; Li, S. K.; Guan, L.-Y.; Guo, Z.; Yin, J.-F.; Gao, L.; Kawanishi, T.; Shimada, A.; Zhang, Q.-p.; Zheng, L.-S.; Liu, Y.-Y.; Feng, X.-X.; Chen, D.-Y.; Takeda, H.; Fan, Y.

10.1101/2021.02.25.432863 — developmental biology — Posted on 2021-03-19

1990 Ex vivo anticoagulants affect human blood platelet biomechanics with implications for high-throughput functional mechanophenotyping.

Sachs, L.; Wesche, J.; Lenkeit, L.; Greinacher, A.; Bender, M.; Otto, O.; Palankar, R.

10.1101/2021.02.17.428074 — cell biology — Posted on 2021-03-19

1991 Quantitative dSTORM super-resolution microscopy localizes Aurora kinase A/AURKA in the mitochondrial matrix

Durel, B.; Kervrann, C.; Bertolin, G.

10.1101/2020.11.20.390948 — cell biology — Posted on 2021-03-19

1992 Perceptual gating of a brainstem reflex facilitates speech understanding in human listeners

Hernandez Perez, H.; Mikiel-Hunter, J. A. D.; McAlpine, D.; Dhar, S.; Boothalingam, S.; Monaghan, J. J. M.; McMahon, C. M.

10.1101/2020.05.31.115444 — neuroscience — Posted on 2021-03-19

1993 Thinking ahead: prediction in context as a keystone of language in humans and machines

Goldstein, A.; Zada, Z.; Buchnik, E.; Schain, M.; Price, A.; Aubrey, B.; Nastase, S. A.; Feder, A.; Emanuel, D.; Cohen, A.; Jansen, A.; Gazula, H.; Choe, G.; Rao, A.; Kim, C.; Casto, C.; Lora, F.; Flinker, A.; Devore, S.; Doyle, W.; Dugan, P.; Friedman, D.; Hassidim, A.; Brenner, M.; Matias, Y.; Norman, K. A.; Devinsky, O.; Hasson, U.

10.1101/2020.12.02.403477 — neuroscience — Posted on 2021-03-19

1994 Development of a novel connectivity-based electric-field modelling approach for individualized targeting of transcranial magnetic stimulation treatment.

Balderston, N. L.; Beer, J. C.; Seok, D.; Makhoul, W.; Deng, Z.-D.; Girelli, T.; Teferi, M.; Smyk, N.; Jaskir, M.; Oathes, D. J.; Sheline, Y. I.

10.1101/2020.12.06.408856 — neuroscience — Posted on 2021-03-19

1995 Radius-Optimized Efficient Template Matching for Lesion Detection from Brain Images

Koley, S.; Dutta, P. K.; Aganj, I.

10.1101/2020.01.10.893099 — neuroscience — Posted on 2021-03-19

1996 Rapid acting antidepressant (2R,6R)-hydroxynorketamine (HNK) targets glucocorticoid receptor signaling: a longitudinal cerebrospinal fluid proteome study

Herzog, D. P.; Perumal, N.; Manicam, C.; Treccani, G.; Nadig, J.; Rossmanith, M.; Engelmann, J.; Jene, T.; Hasch, A.; van der Kooij, M. A.; Lieb, K.; Gassen, N. C.; Grus, F. H.; Mueller, M. B.

10.1101/2020.09.03.280834 — neuroscience — Posted on 2021-03-19

1997 Ion dynamics at the energy-deprived tripartite synapse

Kalia, M.; Meijer, H. G. E.; van Gils, S. A.; van Putten, M. J. A. M.; Rose, C. R.

10.1101/2021.03.19.436129 — biophysics — Posted on 2021-03-19

1998 The loops of the N-SH2 binding cleft do not serve as allosteric switch in SHP2 activation

Anselmi, M.; Hub, J. S.

10.1101/2020.11.18.388447 — biophysics — Posted on 2021-03-19

1999 Seidr: Efficient Calculation of Robust Ensemble Gene Networks

Schiffthaler, B.; van Zalen, E.; Serrano, A.; Street, N. R.; Delhomme, N.

10.1101/250696 — bioinformatics — Posted on 2021-03-19

2000 Cell-Tak coating may cause mis-normalization of Seahorse metabolic flux data

Sima, M.; Martinkova, S.; Kafkova, A.; Pala, J.; Trnka, J.

10.1101/2021.03.19.436150 — biochemistry — Posted on 2021-03-19

2001 Conformity leading self-organised rescue from a suboptimal decision-making bias

Toyokawa, W.; Gaissmaier, W.

10.1101/2021.02.22.432286 — animal behavior and cognition — Posted on 2021-03-19

2002 High throughput genome-wide single cell protein:DNA binding site mapping by targeted insertion of promoters (TIP-seq)

Bartlett, D. A.; Dileep, V.; Henikoff, S.; Gilbert, D. M.

10.1101/2021.03.17.435909 — genomics — Posted on 2021-03-19

2003 Polygenic Scores for Cognitive Abilities and their Association with Different Aspects of General Intelligence - a Deep Phenotyping Approach

Genc, E.; Schlüter, C.; Fraenz, C.; Arning, L.; Metzen, D.; Nguyen, H. P.; Voelkle, M. C.; Streit, F.; Güntürkün, O.; Kumsta, R.; Ocklenburg, S.

10.1101/2020.06.03.131318 — genetics — Posted on 2021-03-19

2004 The taxonomic and functional biogeographies of phytoplankton and zooplankton communities across boreal lakes

St-Gelais, N. F.; Vogt, R. J.; del Giorgio, P. A.; Beisner, B. E.

10.1101/373332 — ecology — Posted on 2021-03-19

2005 The island rule explains consistent patterns of body size evolution in terrestrial vertebrates

Benitez-Lopez, A.; Santini, L.; Gallego-Zamorano, J.; Mila, B.; Walkden, P.; Huijbregts, M. A. J.; Tobias, J. A.

10.1101/2020.05.25.114835 — ecology — Posted on 2021-03-19

2006 Intraflagellar transport trains can turn around without the ciliary tip complex

Nievergelt, A. P.; Zykov, I.; Diener, D. R.; Buchholz, T.-O.; Delling, M.; Diez, S.; Jug, F.; Stepanek, L.; Pigino, G.

10.1101/2021.03.19.436138 — cell biology — Posted on 2021-03-19

2007 Distinct Hypoxia-induced Translational Profiles of Embryonic and Adult-derived Macrophages

Wilcox, N. S.; Yarovinsky, T. O.; Pandya, P.; Ramgolam, V. S.; Moro, A.; Wu, Y.; Nicoli, S.; Hirschi, K. K.; Bender, J. R.

10.1101/2021.03.18.435732 — cell biology — Posted on 2021-03-19

2008 Mechano-transduction via the pectin-FERONIA complex regulates ROP6 GTPase signaling in Arabidopsis

Yang, Z.; Tang, W.; Lin, W.; Li, B.

10.1101/2021.03.17.435899 — cell biology — Posted on 2021-03-19

2009 Deep Learning Shows Cellular Senescence Is a Barrier to Cancer Development

Heckenbach, I.; Ben Ezra, M.; Mkrtchyan, G. V.; Madsen, J. S.; Nielsen, M. H.; Oro, D.; Mortensen, L. H.; Verdin, E.; Westendorp, R.; Scheibye-Knudsen, M.

10.1101/2021.03.18.435987 — cell biology — Posted on 2021-03-19

2010 Nonsense Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells with SF3B1 and U2AF1 Mutations

You, Z.; Cheruiyot, A.; Li, S.; Srivatsan, S. N.; Ahmed, T.; Chen, Y.; Lemacon, D. S.; Li, Y.; Yang, Z.; Wadugu, B. A.; Warner, W.; Pruett-Miller, S. M.; Obeng, E. A.; Link, D. C.; He, D.; Xiao, F.; Wang, X.; Bailis, J. M.; Walter, M. J.

10.1101/2021.03.19.436079 — cell biology — Posted on 2021-03-19

2011 CLEMSite, a software for automated phenotypic screens using light microscopy and FIB-SEM

Serra Lleti, J. M.; Steyer, A. M.; Schieber, N. L.; Neumann, B.; Tischer, C.; Hilsenstein, V.; Holtstrom, M.; Unrau, D.; Kirmse, R.; Lucocq, J. M.; Pepperkok, R.; Schwab, Y.

10.1101/2021.03.19.436113 — cell biology — Posted on 2021-03-19

2012 Optogenetic manipulation of YAP cellular localisation and function

Toh, P. J.; Lai, J. K.; Hermann, A.; Destaing, O.; Sheetz, M. P.; Sudol, M.; Saunders, T. E.

10.1101/2021.03.19.436118 — cell biology — Posted on 2021-03-19

2013 Copper dependent ERK1/2 phosphorylation is essential for the viability of neurons and not glia

Chakraborty, K.; Kar, S.; Rai, B.; Bhagat, R.; Naskar, N.; Seth, P.; Gupta, A.; Bhattacharjee, A.

10.1101/2021.03.18.435926 — cell biology — Posted on 2021-03-19

2014 Conformational specificity of opioid receptors is determined by subcellular location irrespective of agonist

Crilly, S. E.; Ko, W.; Weinberg, Z. Y.; Puthenveedu, M. A.

10.1101/2021.03.18.435866 — cell biology — Posted on 2021-03-19

2015 Cell signaling pathways in human mutant PAX6 corneal cells: an in vitro model for aniridia-related keratopathy

Sloniecka, M.; Vicente, A.; Bystrom, B.; Pedrosa Domellof, F.

10.1101/2021.03.19.436143 — molecular biology — Posted on 2021-03-19

2016 Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor

Zhao, F.; Zhang, C.; Zhou, Q.; Hang, K.; Zou, X.; Chen, Y.; Wu, F.; Rao, Q.; Dai, A.; Yin, W.; Shen, D.-D.; Zhang, Y.; Xia, T.; Stevens, R. C.; Xu, H. E.; Yang, D.; Zhao, L.; Wang, M.-W.

10.1101/2021.03.18.436101 — molecular biology — Posted on 2021-03-19

2017 Thermal stress triggers productive viral infection of a key coral reef symbiont

Grupstra, C.; Howe-Kerr, L. I.; Veglia, A. J.; Bryant, R. L.; Coy, S. R.; Blackwelder, P. L.; Correa, A. M.

10.1101/2021.03.17.435810 — ecology — Posted on 2021-03-19

2018 An RNase III processed, antisense RNA pair regulates a Campylobacter jejuni colonization factor

Svensson, S. L.; Sharma, C. M.

10.1101/2021.03.19.434396 — microbiology — Posted on 2021-03-19

2019 Gallic Acid, a Methyl 3,4-Dihydroxybenzoate Derivative, Induces Neural Stem Cells to Differentiate and Proliferate

Jiang, J.; Liu, W.; Hai, J.; Luo, Y.; Chen, K.; Xin, Y.; Pan, J.; Hu, Y.; Gao, Q.; Xiao, F.; Luo, H.

10.1101/2021.03.01.433474 — neuroscience — Posted on 2021-03-19

2020 Electrophysiological signatures of brain aging in autism spectrum disorder.

Dickinson, A.; Jeste, S.; Milne, E.

10.1101/2021.03.18.434885 — neuroscience — Posted on 2021-03-19

2021 Antagonistic effects of chemical mixtures on the oxidative stress response are silenced by heat stress and reversed under dietary restriction

Suresh Arulalan, K.; Huayta, J.; Stallrich, J. W.; San-Miguel, A.

10.1101/2021.03.17.435857 — physiology — Posted on 2021-03-19

2022 Micro-region transcriptomics of fixed human tissue using Pick-Seq

Maliga, Z.; Nirmal, A. J.; Ericson, N. G.; Boswell, S. A.; U'Ren, L.; Podyminogin, R.; Chow, J.; Chen, Y.-A.; Chen, A. A.; Weinstock, D. M.; Lian, C. G.; Murphy, G. F.; Kaldjian, E. P.; Santagata, S.; Sorger, P. K.

10.1101/2021.03.18.431004 — cancer biology — Posted on 2021-03-19

2023 Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer

Bartolacci, C.; Andreani, C.; Dias do Vale, G.; Berto, S.; Melegari, M.; Crouch, A. C.; Baluya, D. L.; Kemble, G.; Hodges, K.; Starrett, J.; Politi, K.; Starnes, S. L.; Lorenzini, D.; Raso, M. G.; Solis Soto, L.; Behrens, C.; Kadara, H.; Gao, B.; Gerber, D.; Wistuba, I. I.; Minna, J.; McDonald, J.; Scaglioni, P. P.

10.1101/2021.03.18.434804 — cancer biology — Posted on 2021-03-19

2024 Analyzing Assay Redundancy in Metabolomics using Unique Ion Signatures

Shanthamoorthy, P.; Rost, H.

10.1101/2021.03.19.434579 — bioinformatics — Posted on 2021-03-19

2025 Hubness reduction improves clustering and trajectory inference in single-cell transcriptomic data

Amblard, E. C.; Bac, J.; Chervov, A.; Soumelis, V.; Zinovyev, A.

10.1101/2021.03.18.435808 — bioinformatics — Posted on 2021-03-19

2026 Prediction of ligand-receptor pharmacological activities using a combined docking and machine learning approach

Jimenez-Roses, M.; Morgan, B. A.; Jimenez Sigstad, M.; Tran, T. D. Z.; Srivastava, R.; Bunsuz, A.; Borrega Roman, L.; Hompluem, P.; Cullum, S. A.; Harwood, C. R.; Koers, E. J.; Sykes, D. A.; Styles, I. B.; Veprintsev, D. B.

10.1101/2021.03.18.434755 — bioinformatics — Posted on 2021-03-19

2027 A novel Mycobacterium tuberculosis-specific subunit vaccine provides synergistic immunity upon co-administration with Bacillus Calmette-Guerin

Woodworth, J. S.; Strand Clemmensen, H.; Battey, H.; Dijkman, K.; Lindenstrom, T.; Salvador Laureano, R.; Taplitz, R.; Morgan, J.; Aagaard, C.; Rosenkrands, I.; Lindestam Arlehamn, C. S.; Andersen, P.; Mortensen, R.

10.1101/2021.03.18.435784 — immunology — Posted on 2021-03-19

2028 Plasma Membrane Calcium ATPase (PMCA) Regulates Stoichiometry of CD4+ T-cell Compartments

Merino-Wong, M.; Niemeyer, B. A.; Alansary, D.

10.1101/2021.03.18.435950 — immunology — Posted on 2021-03-19

2029 NK cell metabolic adaptation to infection promotes survival and viral clearance.

Victorino, F.; Bigley, T.; Park, E.; Yao, C.-H.; Benoit, J.; Yang, L.-P.; Piersma, S. J.; Lauron, E. J.; Davidson, R. M.; Patti, G. J.; Yokoyama, W. M.

10.1101/2021.03.17.435833 — immunology — Posted on 2021-03-19

2030 Longitudinal allometry of sulcal morphology in health and schizophrenia

Janssen, J.; Alloza, C.; Martinez, C.; Santonja, J.; Pina-Camacho, L.; Macias, P.; Fernandez-Pena, A.; Gonzalez Lois, N.; Buimer, E.; van Haren, N.; Cahn, W.; Castro, J.; Bernardo, M.; Parellada, M.; Arango, C.; Kahn, R.; Hulshoff Pol, H.; Schnack, H.

10.1101/2021.03.17.435797 — neuroscience — Posted on 2021-03-19

2031 Cell cycle gene regulation dynamics revealed by RNA velocity and deep-learning

Molina, N.; Riba, A.; Oravecz, A.; Durik, M.; Jimenez, S.; Alunni, V.; Cerciat, M.; Jung, M.; Kleime, C.; Keyes, W. M.

10.1101/2021.03.17.435887 — systems biology — Posted on 2021-03-19

2032 Amelioration of hemophilia B through CRISPR/Cas9 induced homology-independent targeted integration

Chen, X.; Niu, X.; Liu, Y.; Zheng, R.; Wang, L.; Yang, L.; Lu, J.; Yin, S.; Shao, Y.; Wei, Y.; Pan, J.; Sayed, A.; Ma, X.; Liu, M.; Jing, F.; Liu, M.; Hu, J.; Zhang, X.; Li, D.

10.1101/2021.03.18.435908 — bioengineering — Posted on 2021-03-19

2033 Elimination of GPI2 suppresses glycosylphosphatidylinositol GlcNAc transferase activity and alters GPI glycan modification in Trypanosoma brucei

Jenni, A.; Knüsel, S.; Nagar, R.; Benninger, M.; Häner, R.; Ferguson, M. A. J.; Roditi, I.; Menon, A. K.; Bütikofer, P.

10.1101/2021.03.18.436003 — biochemistry — Posted on 2021-03-19

2034 The archaeal triphosphate tunnel metalloenzyme SaTTM defines structural determinants for the diverse activities in the CYTH protein family

Vogt, M. S.; Ngouoko Nguepbeu, R. R.; Mohr, M. K. F.; Albers, S.-V.; Essen, L.-O.; Banerjee, A.

10.1101/2021.03.18.435988 — biochemistry — Posted on 2021-03-19

2035 MICROBIOTA-MEDIATED COMPETITION BETWEEN DROSOPHILA SPECIES

rombaut, a.; Gallet, R.; Qitout, K.; Samy, M.; Guilhot, R.; Ghirardini, P.; Lazzaro, B. P.; Becher, P. G.; Xuereb, A.; Gibert, P.; Fellous, S.

10.1101/2020.08.05.238055 — evolutionary biology — Posted on 2021-03-19

2036 MafF is an antiviral host factor that suppresses transcription from Hepatitis B Virus core promoter

10.1101/2020.07.29.227793 — microbiology — Posted on 2021-03-19

2037 Temporal Scaling of Human Scalp-Recorded Potentials

Hassall, C. D.; Harley, J.; Kolling, N.; Hunt, L. T.

10.1101/2020.12.11.421180 — neuroscience — Posted on 2021-03-19

2038 The record of Deinotheriidae from the Miocene of the Swiss Jura Mountains (Jura Canton, Switzerland)

Gagliardi, F.; Maridet, O.; Becker, D.

10.1101/2020.08.10.244061 — paleontology — Posted on 2021-03-19

2039 PySTACHIO: Python Single-molecule TrAcking stoiCHiometry Intensity and simulatiOn, a flexible, extensible, beginner-friendly and optimized program for analysis of single-molecule microscopy

Shepherd, J. W.; Higgins, E.; Wollman, A. J.; Leake, M. C.

10.1101/2021.03.18.435952 — biophysics — Posted on 2021-03-19

2040 Mapping Human Pluripotent Stem Cell Derived Erythroid Differentiation by Single-Cell Transcriptome Analysis

Xin, Z.; Zhang, W.; Gong, S.; Zhu, J.; Li, Y.; Zhang, Z.; Fang, X.

10.1101/859777 — developmental biology — Posted on 2021-03-19

2041 Comprehensive mouse gut metagenomecatalog reveals major difference to thehuman counterpart

Kieser, S.; Zdobnov, E.; Trajkovski, M.

10.1101/2021.03.18.435958 — microbiology — Posted on 2021-03-19

2042 Perceptual gating of a brainstem reflex facilitates speech understanding in humans listeners

Hernandez Perez, H.; Mikiel-Hunter, J. A. D.; McAlpine, D.; Dhar, S.; Boothalingam, S.; Monaghan, J. J. M.; McMahon, C. M.

10.1101/2020.05.31.115444 — neuroscience — Posted on 2021-03-19

2043 Effect of high-frequency low-intensity pulsed electric field on protecting SH-SY5Y cells against hydrogen peroxide and β-amyloid-induced cell injury via ERK pathway

Chen, W.-T.; Lin, G.-B.; Kuo, Y.-Y.; Hsieh, C.-H.; Lu, C.-H.; Sun, Y.-K.; Chao, C.-Y.

10.1101/2019.12.30.891499 — neuroscience — Posted on 2021-03-19

2044 Ciliary Hedgehog signaling regulates cell survival to build the facial midline

Abrams, S. R.; Reiter, J. F.

10.1101/2021.03.18.436057 — developmental biology — Posted on 2021-03-18

2045 HIV-1 requires capsid remodelling at the nuclear pore for nuclear entry and integration

Guedan, A.; Donaldson, C. D.; Cosnefroy, O.; Taylor, I. A.; Bishop, K. N.

10.1101/2021.03.18.436028 — microbiology — Posted on 2021-03-18

2046 Does the Zebra Finch Mating Song Circuit Use Spike Times Efficiently?

Nicola, W.; Clopath, C.; Newton, T. R.

10.1101/2021.03.18.436095 — neuroscience — Posted on 2021-03-18

2047 No evidence for a special role of language in feature-based categorization

Benn, Y.; Ivanova, A. A.; Clark, O.; Mineroff, Z.; Seikus, C.; Santos Silva, J.; Varley, R.; Fedorenko, E.

10.1101/2021.03.18.436075 — neuroscience — Posted on 2021-03-18

2048 Manganese toxicity disrupts indole acetic acid homeostasis and suppresses CO2 assimilation reaction in rice plants

Takagi, D.; Ishiyama, K.; Suganami, M.; Ushijima, T.; Fujii, T.; Tazoe, Y.; Kawasaki, M.; Noguchi, K.; Makino, A.

10.1101/2021.03.16.435720 — plant biology — Posted on 2021-03-18

2049 Behavioral context shapes vocal sequences in two anuran species with different repertoire sizes

Bhat, A. S.; Sane, V. A.; S, S. K.; Krishnan, A.

10.1101/2021.03.18.436029 — animal behavior and cognition — Posted on 2021-03-18

2050 Adaptive divergence in shoot gravitropism creates hybrid sterility in an Australian wildflower

Wilkinson, M. J.; Roda, F.; Walter, G. M.; James, M. E.; Nipper, R.; Walsh, J.; Allen, S. L.; North, H. L.; Beveridge, C. A.; Ortiz-Barrientos, D.

10.1101/845354 — evolutionary biology — Posted on 2021-03-18

2051 Infection of immune competent macrophages expressing functional Slc11a1 alters global gene expression, regulation of metal ions, and infection outcomes

Janiszewski, L. N.; Minson, M.; Allen, M. A.; Dowell, R. D.; Palmer, A.

10.1101/2021.03.18.436026 — cell biology — Posted on 2021-03-18

2052 Systematic review of Plasmodium falciparum and Plasmodium vivax polyclonal infections: Impact of prevalence, study population characteristics, and laboratory procedures

Lopez, L.; Koepfli, C.

10.1101/2021.03.18.436023 — microbiology — Posted on 2021-03-18

2053 The Chlamydia trachomatis type III effector TarP coordinates a functional collaboration between the actin nucleators Formin 1 and Arp2/3 during invasion

Romero, M. D.; Carabeo, C. A.

10.1101/2021.03.18.436027 — microbiology — Posted on 2021-03-18

2054 Critical behaviour of the stochastic Wilson-Cowan model

De Candia, A.; Sarracino, A.; Apicella, I.; de Arcangelis, L.

10.1101/2021.03.18.436022 — neuroscience — Posted on 2021-03-18

2055 Personalized Closed-Loop Brain Stimulation for Effective Neurointervention Across Participants

van Bueren, N.; Reed, T.; Nguyen, V.; Sheffield, J.; van der Ven, S.; Osborne, M.; Kroesbergen, E.; Cohen Kadosh, R.

10.1101/2021.03.18.436018 — neuroscience — Posted on 2021-03-18

2056 The phosphoproteome of rice leaves responds to water and nitrogen supply

Hamzelou, S.; Melino, V. J.; Plett, D. C.; Kamath, K. S.; Nawrocki, A.; Larsen, M. R.; Atwell, B. J.; Haynes, P. A.

10.1101/2021.03.15.435047 — plant biology — Posted on 2021-03-18

2057 Brain Water as a Function of Age and Weight in Normal Rats

Gottschalk, A.; Scafidi, S.; Toung, T.

10.1101/2021.03.18.436025 — physiology — Posted on 2021-03-18

2058 Testing in vitro toxicity of nanoparticles in 3D cell culture with various extracellular matrix scaffold

Choi, J. W.; Bae, S.-H.; Kim, I. Y.; Kwak, M.; Lee, T. G.; Heo, M. B.

10.1101/2021.03.18.436024 — pharmacology and toxicology — Posted on 2021-03-18

2059 The N-terminal domain of RfaH plays an active role in protein fold-switching

Galaz-Davison, P.; Roman, E. A.; Ramirez-Sarmiento, C. A.

10.1101/2021.03.18.436019 — biophysics — Posted on 2021-03-18

2060 DGCyTOF: deep learning with graphic cluster visualization to predict cell types of single cell mass cytometry data

Cheng, L.; Karkhanis, P.; Gokbag, B.; Li, L.

10.1101/2021.03.18.436021 — bioinformatics — Posted on 2021-03-18

2061 Binding affinity prediction for protein-ligand complex using deep attention mechanism based on intermolecular interactions

Seo, S.; Choi, J.; Park, S.; Ahn, J.

10.1101/2021.03.18.436020 — bioinformatics — Posted on 2021-03-18

2062 The SAGA and NuA4 component Tra1 regulates Candida albicans drug resistance and pathogenesis

Razzaq, I.; Berg, M. D.; Jiang, Y.; Genereaux, J.; Uthayakumar, D.; Kim, G. H.; Brandl, C. J.; Lajoie, P.; Shapiro, R. S.

10.1101/2021.03.17.435915 — microbiology — Posted on 2021-03-18

2063 CHIPS: A Snakemake pipeline for quality control and reproducible processing of chromatin profiling data

Taing, L.; Cousins, C.; Bai, G.; Paloma, C.; Qiu, X.; Brown, M.; Meyer, C. A.; Liu, X. S.; Long, H. W.; Tang, M.

10.1101/2021.03.09.434676 — bioinformatics — Posted on 2021-03-18

2064 Transcriptomic analysis reveals that severity of infectious bursal disease in White Leghorn inbred chicken lines is associated with greater bursal inflammation in vivo and more rapid induction of pro-inflammatory responses in primary bursal cells stimulated ex vivo.

Asfor, A. S.; Nazki, S.; Reddy, V. R.; Campbell, E.; Dulwich, K. L.; Giotis, E. S.; Skinner, M. A.; Broadbent, A. J.

10.1101/2021.03.18.436042 — microbiology — Posted on 2021-03-18

2065 Curtobacterium glycinis sp. nov. from Glycine max, Curtobacterium gossypii sp. nov. from Gossypium hirsutum and Curtobacterium oryzae sp. nov. from Oryza sativa, three new Curtobacterium species and endophytes from agricultural crops

Seaton, S.; Lemaire, J.; Inderbitzin, P.; Knight-Connoni, V.; White, J. F.; Trujillo, M. E.

10.1101/2021.03.18.434777 — microbiology — Posted on 2021-03-18

2066 Temporal Scaling of Human Scalp-Recorded Potentials During Interval Estimation

Hassall, C. D.; Harley, J.; Kolling, N.; Hunt, L. T.

10.1101/2020.12.11.421180 — neuroscience — Posted on 2021-03-18

2067 Analogous computations in working memory input, output and motor gating: Electrophysiological and computational modeling evidence

Rac-Lubashevsky, R.; Frank, M. J.

10.1101/2020.12.21.423791 — neuroscience — Posted on 2021-03-18

2068 Twitches emerge postnatally during quiet sleep in human infants and are synchronized with sleep spindles

Sokoloff, G.; Dooley, J. C.; Glanz, R. M.; Wen, R. Y.; Hickerson, M. M.; Evans, L. G.; Laughlin, H. M.; Apfelbaum, K. S.; Blumberg, M. S.

10.1101/2021.02.17.431688 — neuroscience — Posted on 2021-03-18

2069 Efficiency of the synthetic self-splicing RiboJ ribozyme is robust to cis- and trans-changes in genetic background

Vlkova, M.; Morampalli, B.; Silander, O. K.

10.1101/2021.03.17.435894 — synthetic biology — Posted on 2021-03-18

2070 Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion

Schlee Villodre, E.; Hu, X.; Larson, R. A.; Finetti, P.; Gomez, K.; Balema, W.; Stecklein, S. R.; Santiago-Sanchez, G.; Krishnamurthy, S.; Song, J.; Su, X.; Ueno, N. T.; Tripathy, D.; Van Laere, S.; Bertucci, F.; Vivas-Mejia, P.; Woodward, W. A.; Debeb, B. G.

10.1101/2021.03.18.436052 — cancer biology — Posted on 2021-03-18

2071 Novel epigenetic-metabolic inhibitor combination treatment blocks platinum-induced ovarian cancer stem cell enrichment

Sood, R.; Xiao, S.; Sriramkumar, S.; Hassel, C.; Nephew, K. P.; O'Hagan, H. M.

10.1101/2021.03.18.435878 — cancer biology — Posted on 2021-03-18

2072 Tumor secreted extracellular vesicles regulate T-cell costimulation and can be manipulated to induce tumor-specific T-cell responses

Zhao, X.; Yuan, C.; Wangmo, D.; Subramanian, S.

10.1101/2020.04.22.055632 — cancer biology — Posted on 2021-03-18

2073 Dynamic changes of genomic and transcriptomic tumor diversity during melanoma progression

Moore, A. L.; Dimitrakopoulos, C.; Flückiger-Mangual, S.; Frischknecht, L.; Beisel, C.; Krek, W.; Beerenwinkel, N.

10.1101/2021.03.18.435947 — cancer biology — Posted on 2021-03-18

2074 Sustained software development, not number of citations or journal choice, is indicative of accurate bioinformatic software

Gardner, P. P.; Paterson, J. M.; McGimpsey, S. R.; Ashari Ghomi, F.; Umu, S. U.; Pawlik, A.; Gavryushkin, A.; Black, M. A.

10.1101/092205 — bioinformatics — Posted on 2021-03-18

2075 Detectability of biotin tags by LC-MS/MS

Nierves, L.; Lange, P. F.

10.1101/2020.12.30.424786 — biochemistry — Posted on 2021-03-18

2076 DNA methylation is not a driver of gene expression reprogramming in young honey bee workers

Cardoso Junior, C.; Yagound, B.; Ronai, I.; Remnant, E. J.; Hartfelder, K.; Oldroyd, B.

10.1101/2021.03.12.435154 — genomics — Posted on 2021-03-18

2077 Reverse Transcriptase Real-Time PCR Assay for the Rapid Enumeration of Live Candida auris from the Healthcare Environment

Freitas, B. L.; Leach, L.; Chaturvedi, V.; Chaturvedi, S.

10.1101/2021.03.18.436063 — molecular biology — Posted on 2021-03-18

2078 Investigating molecular mechanisms of 2A-stimulated ribosomal pausing and frameshifting in Theilovirus

Hill, C. H.; Cook, G. M.; Napthine, S.; Kibe, A.; Brown, K.; Caliskan, N.; Firth, A. E.; Graham, S. C.; Brierley, I.

10.1101/2020.08.11.245068 — molecular biology — Posted on 2021-03-18

2079 In Situ Optical Quantification of Extracellular Electron Transfer using Plasmonic Metal Oxide Nanocrystals

Graham, A. J.; Gibbs, S. L.; Saez Cabezas, C. A.; Wang, Y.; Green, A. M.; Milliron, D. J.; Keitz, B. K.

10.1101/2020.10.13.336008 — microbiology — Posted on 2021-03-18

2080 Respiratory tract explant infection dynamics of influenza A virus in California sea lions, northern elephant seals, and rhesus macaques

Liu, H.; Plancarte, M.; Ball, E. E.; Weiss, C. M.; Gonzales-Viera, O.; Holcomb, K.; Ma, Z.-M.; Allen, A. M.; Reader, J. R.; Duignan, P. J.; Halaska, B.; Khan, Z.; Kriti, D.; Dutta, J.; van Bakel, H.; Jackson, K.; Pesavento, P. A.; Boyce, W. M.; Coffey, L. L.

10.1101/2020.10.15.342055 — microbiology — Posted on 2021-03-18

2081 The Vaginal Microbiome in Women of Reproductive Age with Healthy Weight versus Overweight/Obesity

Allen, N. G.; Edupuganti, L.; Edwards, D. J.; Jimenez, N. R.; Buck, G. A.; Jefferson, K. K.; Strauss, J. F.; Vaginal Microbiome Consortium, ; Wickham, E. P.; Fettweis, J. M.

10.1101/2021.03.18.435996 — microbiology — Posted on 2021-03-18

2082 Differences in the gut microbiomes of distinct ethnicities within the same geographic area are linked to host metabolic health

Ang, Q. Y.; Alba, D. L.; Upadhyay, V.; Bisanz, J. E.; Cai, J.; Lee, H. L.; Barajas, E.; Wei, G.; Noecker, C.; Patterson, A. D.; Koliwad, S. K.; Turnbaugh, P. J.

10.1101/2020.10.23.352807 — microbiology — Posted on 2021-03-18

2083 High prevalence and diversity of beta-lactamase-encoding bacteria in cryosoils and ancient permafrost

Rigou, S.; Christo-Foroux, E.; Santini, S.; Goncharov, A.; Strauss, J.; Grosse, G.; Fedorov, A. N.; Labadie, K.; Abergel, C.; Claverie, J.-M.

10.1101/2021.03.17.435775 — microbiology — Posted on 2021-03-18

2084 Click evoked Middle Ear Muscle Reflex: Spectral and Temporal Aspects

Boothalingam, S.; Goodman, S. S.

10.1101/2020.08.24.265462 — neuroscience — Posted on 2021-03-18

2085 Neural systems underlying the learning of cognitive effort costs

Sayali, C.; Badre, D.

10.1101/2020.06.08.139618 — neuroscience — Posted on 2021-03-18

2086 Morphological principles of neuronal mitochondria

Mendelsohn, R.; Garcia, G. C.; Bartol, T. M.; Lee, C. T.; Khandelwal, P.; Liu, E.; Spencer, D. J.; Husar, A.; Bushong, E. A.; Phan, S.; Perkins, G.; Ellisman, M. H.; Skupin, A.; Sejnowski, T. J.; Rangamani, P.

10.1101/2021.03.15.435547 — neuroscience — Posted on 2021-03-18

2087 SPIRO - the automated Petri plate imaging platform designed by biologists, for biologists

Ohlsson, J. A.; Leong, J. X.; Elander, P. H.; Dauphinee, A. N.; Ballhaus, F.; Johansson, J.; Lommel, M.; Hofmann, G.; Betner, S.; Sandgren, M.; Schumacher, K.; Bozhkov, P. V.; Minina, A. E. A.

10.1101/2021.03.15.435343 — plant biology — Posted on 2021-03-18

2088 A Degenerate PCNA-Interacting Peptide (DPIP) box targets RNF168 to replicating DNA to limit 53BP1 signaling

Yang, Y.; Jayaprakash, D.; Hollingworth, R.; Chen, S.; Jablonski, A.; Mutter-Rottmayer, E.; Gao, Y.; Anand Ramlal, J.; An, J.; Chen, X.; Pearce, K.; Blanchet, S.-A.; Fradet-Turcotte, A.; Stewart, G.; Vaziri, C.

10.1101/2021.03.17.435897 — cancer biology — Posted on 2021-03-18

2089 Comprehensive patient-level classification and quantification of driver events in TCGA PanCanAtlas cohorts

Vyatkin, A. D.; Otnyukov, D. V.; Leonov, S. V.; Belikov, A. V.

10.1101/2021.03.17.435828 — cancer biology — Posted on 2021-03-18

2090 PI3Kβ inhibition restores ALK inhibitor sensitivity in ALK-rearranged lung cancer

Wennerberg, K.; Verschuren, E. W.; Talwelkar, S.; Mäyränpää, M. I.; Schüler, J.; Linnavirta, N.; Hemmes, A.; Adinolfi, S.; Kankainen, M.; Sommergruber, W.; Levonen, A.-L.; Räsänen, J.; Knuuttila, A.

10.1101/2021.03.18.435801 — cancer biology — Posted on 2021-03-18

2091 Momelotinib is a highly potent inhibitor of FLT3-mutant AML

Azhar, M.; Kincaid, Z.; Kesarwani, M.; Latif, T.; Starczynowski, D.; Azam, M.

10.1101/2021.03.18.436047 — cancer biology — Posted on 2021-03-18

2092 Structural intermediates observed only in intact Escherichia coli indicate a mechanism for TonB-dependent transport

Nilaweera, T. D.; Nyenhuis, D. A.; Cafiso, D. S.

10.1101/2021.03.18.436049 — biophysics — Posted on 2021-03-18

2093 Phospholipids stabilize binding of pituitary adenylate cyclase-activating peptide to vasoactive intestinal polypeptide receptor

Thomas, N.; Agrawal, A.

10.1101/2021.03.18.436073 — biophysics — Posted on 2021-03-18

2094 Reconstructing complex cancer evolutionary histories from multiple bulk DNA samples using Pairtree

Wintersinger, J. A.; Dobson, S. M.; Stein, L. D.; Dick, J. E.; Morris, Q.

10.1101/2020.11.06.372219 — bioinformatics — Posted on 2021-03-18

2095 Alleloscope: Integrative single cell analysis of allele-specific copy number alterations and chromatin accessibility in cancer

Wu, C.-Y.; Lau, B. T.; Kim, H.; Sathe, A.; Grimes, S. M.; Ji, H. P.; Zhang, N. R.

10.1101/2020.10.23.349407 — bioinformatics — Posted on 2021-03-18

2096 Sub-second multi-channel magnetic control of select neural circuits in behaving flies

Sebesta, C.; Torres, D.; Wang, B.; Li, Z.; Duret, G.; Jiang, K.; Xiao, Z.; Zhang, Q.; Colvin, V.; Goetz, S. M.; Peterchev, A. V.; Dierick, H.; Bao, G.; Robinson, J. T.

10.1101/2021.03.15.435264 — bioengineering — Posted on 2021-03-18

2097 Potential Role of Red Palm Oil Supplemented Diet on Oxidative Stress Enzymes in Plasmodium berghei Induced Malaria

Adeleke, T. D.; Adejumobi, O.

10.1101/2021.03.18.435769 — biochemistry — Posted on 2021-03-18

2098 Angiotensin II disrupts the cytoskeletal architecture of human urine-derived podocytes and results in activation of the renin-angiotensin system

Erichsen, L.; Bohndorf, M.; Rahman, M. S.; Wruck, W.; Adjaye, J.

10.1101/2021.03.18.436037 — cell biology — Posted on 2021-03-18

2099 The B1.351 and P.1 variants extend SARS-CoV-2 host range to mice

Montagutelli, X.; Prot, M.; Levillayer, L.; Baquero Salazar, E.; Jouvion, G.; Conquet, L.; Donati, F.; Albert, M.; Gambaro, F.; Behillil, S.; Enouf, V.; Rousset, D.; Jaubert, J.; Rey, F.; van der Werf, S.; Simon-Loriere, E.

10.1101/2021.03.18.436013 — microbiology — Posted on 2021-03-18

2100 Large-scale computational discovery and analysis of virus-derived microbial nanocompartments

Andreas, M. P.; Giessen, T. W.

10.1101/2021.03.18.436031 — microbiology — Posted on 2021-03-18

2101 Pro-autoimmune allele of tyrosine phosphatase, PTPN22, enhances tumor immunity

Orozco, R. C.; Marquardt, K.; Mowen, K.; Sherman, L. A.

10.1101/2021.03.17.435898 — immunology — Posted on 2021-03-18

2102 Antigen-specific stimulation and expansion of CAR-T cells using membrane vesicles as target cell surrogates

Ukrainskaya, V. M.; Rubtsov, Y. P.; Pershin, D. S.; Podoplelova, N. A.; Terekhov, S. S.; Yaroshevich, I. A.; Sokolova, A. I.; Bagrov, D. V.; Kulakovskaya, E. A.; Shipunova, V. O.; Deyev, S. M.; Maksimov, E. G.; Markov, O. V.; Oshchepkova, A. L.; Zenkova, M. A.; Xie, J.; Gabibov, A. G.; Maschan, M. A.; Stepanov, A. V.; Lerner, R. A.

10.1101/2021.03.18.435976 — immunology — Posted on 2021-03-18

2103 Type II alveolar cells with constitutive expression of MHCII and limited antigen presentation capacity contribute to improved respiratory viral disease outcomes

Toulmin, S. A.; Bhadiadra, C.; Paris, A. J.; Lin, J. H.; Katzen, J.; Basil, M. C.; Morrisey, E. E.; Worthen, G. S.; Eisenlohr, L. C.

10.1101/2021.03.18.435984 — immunology — Posted on 2021-03-18

2104 Structure-function analysis of purified proanthocyanidins reveals a role for polymer size in suppressing inflammatory responses

Andersen-Civil, A.; Leppa, M. M.; Thamsborg, S. M.; Salminen, J.-P.; Williams, A. R.

10.1101/2021.03.18.436058 — immunology — Posted on 2021-03-18

2105 Decreased synthesis and variable gene transcripts of oxytocin in a domesticated avian species

Tobari, Y.; Theofanopoulou, C.; Mori, C.; Sato, Y.; Marutani, M.; Fujioka, S.; Konno, N.; Suzuki, K.; Furutani, A.; Hakataya, S.; Yao, C.-T.; Yang, E.-Y.; Tsai, C.-R.; Tang, P.-C.; Chen, C.-F.; Boeckx, C.; Jarvis, E.; Okanoya, K.

10.1101/2021.03.17.435911 — neuroscience — Posted on 2021-03-18

2106 Peer presence increases adolescents' prosocial behavior by speeding the evaluation of rewards for others

Sullivan, N. J.; Li, R.; Huettel, S. A.

10.1101/2021.03.17.435800 — neuroscience — Posted on 2021-03-18

2107 Behaviour-driven Arc expression is greater in dorsal than ventral CA1 regardless of task or sex differences.

Lee, J. Q.; McHugh, R.; Morgan, E.; Sutherland, R. J.; McDonald, R. J.

10.1101/2021.03.17.435850 — neuroscience — Posted on 2021-03-18

2108 Closed-loop auditory stimulation method to modulate sleep slow waves and motor learning performance in rats

Moreira, C. G.; Baumann, C. R.; Scandella, M.; Nemirovsky, S. I.; Leach, S.; Huber, R.; Noain, D.

10.1101/2021.03.17.435881 — neuroscience — Posted on 2021-03-18

2109 Accuracy and precision in super-resolution MRI: Enabling spherical tensor diffusion encoding at ultra-high b-values and high resolution

Vis, G.; Nilsson, M.; Westin, C.-F.; Szczepankiewicz, F.

10.1101/2021.03.17.435819 — neuroscience — Posted on 2021-03-18

2110 ENCODING OF LIMB STATE BY SINGLE NEURONS IN THE CUNEATE NUCLEUS OF AWAKE MONKEYS

Versteeg, C.; Rosenow, J. M.; Bensmaia, S. J.; Miller, L. E.

10.1101/2021.03.17.435880 — neuroscience — Posted on 2021-03-18

2111 Variability and thermal modulation of locomotor statistics in zebrafish

Le Goc, G.; Karpenko, S.; Bormuth, V.; Candelier, R.; Debregeas, G.

10.1101/2021.03.17.435787 — animal behavior and cognition — Posted on 2021-03-18

2112 Glucoregulation and coping behavior after chronic stress: sex differences across the lifespan

Dearing, C.; Morano, R.; Ptaskiewicz, E.; Mahbod, P.; Scheimann, J. R.; Franco-Villanueva, A.; Wulsin, L.; Myers, B.

10.1101/2021.03.17.435842 — animal behavior and cognition — Posted on 2021-03-18

2113 Myosin turnover controls actomyosin contractile instability

Thiyagarajan, S.; Wang, S.; Chew, T. G.; Huang, J.; BALASUBRAMANIAN, M.; O'Shaughnessy, B.

10.1101/2021.03.18.436017 — cell biology — Posted on 2021-03-18

2114 Regulation of transcriptional bursting by core promoter elements in the Drosophila embryo

Yokoshi, M.; Cambon, M.; Fukaya, T.

10.1101/2021.03.18.435761 — molecular biology — Posted on 2021-03-18

2115 Phosphorylation of Ribosomal Protein S6 differentially affects mRNA translation based on ORF length

Bohlen, J.; Teleman, A. A.

10.1101/2021.03.18.436059 — molecular biology — Posted on 2021-03-18

2116 Comprehensive mouse gut metagenomecatalog reveals major difference to thehuman counterpart

Trajkovski, M.; Kieser, S.; Zdobnov, E.

10.1101/2021.03.18.435958 — microbiology — Posted on 2021-03-18

2117 Establishment and Resilience of Transplanted Gut Microbiota in Aged Mice

Wang, Y.; Tang, J.; Lv, Q.; Tan, Y.; Dong, X.; Liu, H.; Zhao, N.; He, Z.; Kou, Y.; Tan, Y.; Liu, X.-a.; Wang, L.; Liu, Y.-Y.; Dai, L.

10.1101/2021.03.18.435923 — microbiology — Posted on 2021-03-18

2118 Groundwater bacterial communities evolve over time, exhibiting oscillating similarity patterns in response to recharge

Yan, L.; Hermans, S.; Totsche, K. U.; Lehmann, R.; Herrmann, M.; Kuesel, K.

10.1101/2021.03.18.434713 — microbiology — Posted on 2021-03-18

2119 Transcription Factor NF-κB Unravels Nucleosomes

Stormberg, T.; Filliaux, S.; Baughman, H.; Komives, E.; Lyubchenko, Y. L.

10.1101/2021.03.18.436050 — biophysics — Posted on 2021-03-18

2120 An efficient urine peptidomics workflow identifies chemically defined dietary gluten peptides from patients with celiac disease

Palanski, B. A.; Weng, N.; Zhang, L.; Hilmer, A. J.; Fall, L. A.; Swaminathan, K.; Jabri, B.; Sousa, C.; Fernandez-Becker, N. Q.; Khosla, C.; Elias, J. E.

10.1101/2021.03.17.435829 — biochemistry — Posted on 2021-03-18

2121 β-Carotene oxidation products - function and safety

Burton, G. W.; Mogg, T. J.; Riley, W. W.; Nickerson, J. G.

10.1101/2021.03.18.436000 — biochemistry — Posted on 2021-03-18

2122 Ultrastructural plasma membrane asymmetries in tension and curvature promote yeast cell fusion

Muriel, O.; Michon, L.; Kukulski, W.; Martin, S. G.

10.1101/2021.03.18.435973 — cell biology — Posted on 2021-03-18

2123 Proteomic Organellar Mapping Reveals Modulation of Peroxisomes by HIV-1

Oom, A. L.; Stoneham, C. A.; Lewinski, M. K.; Richards, A.; Wozniak, J.; Gonzalez, D.; Krogan, N. J.; Guatelli, J.

10.1101/2021.03.17.435902 — cell biology — Posted on 2021-03-18

2124 Tight nanoscale clustering of Fc gamma-receptors using DNA origami promotes phagocytosis

Kern, N.; Dong, R.; Douglas, S. M.; Vale, R. D.; Morrissey, M. A.

10.1101/2021.03.18.436011 — cell biology — Posted on 2021-03-18

2125 Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling

Hillen, H. S.; Lavdovskaia, E.; Nadler, F.; Hanitsch, E.; Linden, A.; Bohnsack, K. E.; Urlaub, H.; Richter-Dennerlein, R.

10.1101/2021.03.17.435767 — molecular biology — Posted on 2021-03-18

2126 Genomics-informed insights into microbial degradation of N,N-dimethylformamide

Li, J.; Dijkstra, P.; Lu, Q.; Wang, S.; Chen, S.; Li, D.; Wang, Z.; Jia, Z.; Wang, L.; Shim, H.

10.1101/2021.03.18.435917 — microbiology — Posted on 2021-03-18

2127 The Conserved Colletotrichum spp. Effector CEC3 Induces Nuclear Expansion and Cell Death in Plants

Tsushima, A.; Narusaka, M.; Gan, P.; Kumakura, N.; Hiroyama, R.; Kato, N.; Takahashi, S.; Takano, Y.; Narusaka, Y.; Shirasu, K.

10.1101/2021.03.18.435704 — microbiology — Posted on 2021-03-18

2128 PySTACHIO: Python Single-molecule TrAcking stoiCHiometry Intensity and simulatiOn, a flexible, extensible, beginner-friendly and optimized program for analysis of single-molecule microscopy data

Shepherd, J. W.; Higgins, E.; Wollman, A. J.; Leake, M. C.

10.1101/2021.03.18.435952 — biophysics — Posted on 2021-03-18

2129 Time-lagged Independent Component Analysis of Random Walks and Protein Dynamics

Schultze, S.; Grubmueller, H.

10.1101/2021.03.18.435940 — biophysics — Posted on 2021-03-18

2130 The Dynamic Continuum of Nanoscale Peptide Assemblies Facilitates Endocytosis and Endosomal Escape

He, H.; Guo, J.; Xu, J.; Wang, J.; Liu, S.; Xu, B.

10.1101/2021.03.18.435896 — biochemistry — Posted on 2021-03-18

2131 Genetic variability associated with OAS1 expression in myeloid cells increases the risk of Alzheimer's disease and severe COVID-19 outcomes

Magusali, N.; Graham, A. C.; Piers, T. M.; Panichnantakul, P.; Yaman, U.; Shoai, M.; Reynolds, R. H.; Botia, J. A.; Brookes, K. J.; Guetta-Baranes, T.; Bellou, E.; Bayram, S.; Sokolova, D.; Ryten, M.; Sala Frigerio, C.; Escott-Price, V.; Morgan, K.; Pocock, J. M.; Hardy, J.; Salih, D. A.

10.1101/2021.03.16.435702 — genetics — Posted on 2021-03-18

2132 Stonewall prevents expression of testis-enriched genes and binds to insulator elements in D. melanogaster

Zinshteyn, D.; Barbash, D. A.

10.1101/2021.03.18.435951 — genetics — Posted on 2021-03-18

2133 The mechanosensitive Ca2+-permeable ion channel PIEZO1 promotes satellite cell function in skeletal muscle regeneration

Hirano, K.; Tsuchiya, M.; Takabayashi, S.; Nagao, K.; Kitajima, Y.; Ono, Y.; Nonomura, K.; Mori, Y.; Umeda, M.; Hara, Y.

10.1101/2021.03.18.435982 — cell biology — Posted on 2021-03-18

2134 Identification of guanylyltransferase activity in the SARS-CoV-2 RNA polymerase

Walker, A. P.; Fan, H.; Keown, J. R.; Grimes, J.; Fodor, E.

10.1101/2021.03.17.435913 — microbiology — Posted on 2021-03-18

2135 EEG-based detection of the locus of auditory attention with convolutional neural networks

Vandecappelle, S.; Deckers, L.; Das, N.; Hossein Ansari, A.; Bertrand, A.; Francart, T.

10.1101/475673 — neuroscience — Posted on 2021-03-18

2136 C-Jun N-terminal kinase post-translational regulation of pain-related Acid-Sensing Ion Channels 1b and 3

Verkest, C.; Diochot, S.; Lingueglia, E.; Baron, A.

10.1101/2021.03.18.435937 — neuroscience — Posted on 2021-03-18

2137 Proprioception-based movement goals support imitation and are disrupted in apraxia

Isaacs, M. W.; BUXBAUM, L. J.; Wong, A. L.

10.1101/2021.03.17.435845 — neuroscience — Posted on 2021-03-18

2138 A novel SARS-CoV-2 related virus with complex recombination isolated from bats in Yunnan province, China

Li, L.; Wang, J.; Ma, X.; Li, J.; Yang, X.; Shi, W.; Duan, Z.

10.1101/2021.03.17.435823 — zoology — Posted on 2021-03-18

2139 Semaphorin 3C attracts MGE-derived cortical interneurons in the deepmigratory stream guiding them into the developing neocortex

Aiello, K.; Bolz, J.

10.1101/2021.03.18.435991 — developmental biology — Posted on 2021-03-18

2140 Mutational escape from the polyclonal antibody response to SARS-CoV-2 infection is largely shaped by a single class of antibodies

Greaney, A. J.; Starr, T. N.; Barnes, C. O.; Weisblum, Y.; Schmidt, F.; Caskey, M.; Gaebler, C.; Agudelo, M.; Finkin, S.; Wang, Z.; Poston, D.; Muecksch, F.; Hatziioannou, T.; Bieniasz, P. D.; Robbiani, D. F.; Nussenzweig, M. C.; Bjorkman, P. J.; Bloom, J. D.

10.1101/2021.03.17.435863 — microbiology — Posted on 2021-03-18

2141 Myocarditis in naturally infected pets with the British variant of COVID-19

Ferasin, L.; Fritz, M.; Ferasin, H.; Becquart, P.; Legros, V.; Leroy, E. M.

10.1101/2021.03.18.435945 — microbiology — Posted on 2021-03-18

2142 A single BNT162b2 mRNA dose elicits antibodies with Fc-mediated effector functions and boost pre-existing humoral and T cell responses

Tauzin, A.; Nayrac, M.; Benlarbi, M.; Gong, S. Y.; Gasser, R.; Beaudoin-Bussieres, G.; Brassard, N.; Laumaea, A.; Vezina, D.; Prevost, J.; Anand, S. P.; Bourassa, C.; Gendron-Lepage, G.; Medjahed, H.; Goyette, G.; Niessl, J.; Tastet, O.; Gokool, L.; Morrisseau, C.; Arlotto, P.; Stamatatos, L.; McGuire, A. T.; Larochelle, C.; Uchil, P.; Lu, M.; Mothes, W.; De Serres, G.; Moreira, S.; Roger, M.; Richard, J.; Martel-Laferriere, V.; Duerr, R.; Tremblay, C.; Kaufmann, D. E.; Finzi, A.

10.1101/2021.03.18.435972 — immunology — Posted on 2021-03-18

2143 Sequence determinants of human gene regulatory elements

Sahu, B.; Hartonen, T.; Pihlajamaa, P.; Wei, B.; Dave, K.; Zhu, F.; Kaasinen, E.; Lidschreiber, K.; Lidschreiber, M.; Daub, C. O.; Cramer, P.; Kivioja, T.; Taipale, J.

10.1101/2021.03.18.435942 — genomics — Posted on 2021-03-18

2144 Geographic Confounding in Genome-Wide Association Studies

Abdellaoui, A.; Verweij, K. J. H.; Nivard, M. G.

10.1101/2021.03.18.435971 — genetics — Posted on 2021-03-18

2145 The molecular logic of the self-organization of primitive streak and neuroectoderm fates

Russo, L.; Sladitschek, H. L.; Neveu, P. A.

10.1101/2021.03.18.435967 — developmental biology — Posted on 2021-03-18

2146 Fronto-medial theta coordinates posterior maintenance of working memory content

Ratcliffe, O.; Shapiro, K.; Staresina, B.

10.1101/2021.03.18.435966 — neuroscience — Posted on 2021-03-18

2147 Engineering the AEG1 promoter from cotton to develop male sterile lines

Soni, K. K.; Mehrotra, A. K.; Burma, P. K.

10.1101/2021.03.18.435223 — plant biology — Posted on 2021-03-18

2148 The fungal root endophyte Serendipita vermifera displays inter-kingdom synergistic beneficial effects with the microbiota in Arabidopsis thaliana and barley

Mahdi, L. K.; Miyauchi, S.; Uhlmann, C.; Garrido-Oter, R.; Langen, G.; Wawra, S.; Niu, Y.; Robertson-Albertyn, S.; Bulgarelli, D.; Parker, J. E.; Zuccaro, A.

10.1101/2021.03.18.435831 — plant biology — Posted on 2021-03-18

2149 Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2

Tayeb-Fligelman, E.; Cheng, X.; Tai, C.; Bowler, J. T.; Griner, S.; Sawaya, M. R.; Seidler, P. M.; Jiang, Y. X.; Lu, J.; Rosenberg, G. M.; Salwinski, L.; Abskharon, R.; Zee, C.-T.; Hou, K.; Li, Y.; Boyer, D.; Murray, K. A.; Falcon, G.; Anderson, D. H.; Cascio, D.; Saelices, L.; Damoiseaux, R.; Guo, F.; Eisenberg, D.

10.1101/2021.03.05.434000 — biochemistry — Posted on 2021-03-18

2150 Drug development of an affinity enhanced, broadly neutralizing heavy chain-only antibody that restricts SARS-CoV-2 in rodents

Schepens, B.; van Schie, L.; Nerinckx, W.; Roose, K.; Van Breedam, W.; Fijalkowska, D.; Devos, S.; Weyts, W.; De Cae, S.; Vanmarcke, S.; Lonigro, C.; Eeckhaut, H.; Van Herpe, D.; Borloo, J.; Oliveira, A. F.; Catani, J. P.; Creytens, S.; De Vlieger, D.; Michielsen, G.; Marchan, J. C. Z.; Moschonas, G. D.; Rossey, I.; Sedeyn, K.; Van Hecke, A.; Zhang, X.; Langendries, L.; Jacobs, S.; ter Horst, S.; Seldeslachts, L.; Liesenborghs, L.; Boudewijns, R.; Tibaut, H. J.; Dallmeier, K.; Vande Velde, G.; Weynand, B.; Beer, J.; Schnepf, D.; Ohnemus, A.; Remory, I.; Foo, C. S.-Y.; Abdelnabi, R.; Maes, P.;

10.1101/2021.03.08.433449 — molecular biology — Posted on 2021-03-18

2151 A map of binary SARS-CoV-2 protein interactions implicates host immune regulation and ubiquitination

Kim, D.-K.; Weller, B.; Lin, C.-W.; Sheykhkarimli, D.; Knapp, J. J.; Kishore, N.; Sauer, M.; Rayhan, A.; Young, V.; Marin-de la Rosa, N.; Pogoutse, O.; Spirohn, K.; Strobel, A.; Laval, F.; Schwehn, P.; Li, R.; Simin, R.; Altmann, M.; Cassonnet, P.; Dugied, G.; Cote, A. G.; Elorduy Vergara, L.; Hazelwood, I.; Liu, B. B.; Nguyen, M.; Pandiarajan, R.; Rodriguez Coloma, P. A.; Willems, L.; Twizere, J.-C.; Demeret, C.; Jacob, Y.; Hao, T.; Hill, D. E.; Falter, C.; Vidal, M.; Calderwood, M. A.; Roth, F. P.; Falter-Braun, P.

10.1101/2021.03.15.433877 — systems biology — Posted on 2021-03-18

2152 Enhancing the localization precision of single molecule localization microscopy by analyzing Brownian motion of individual fluorescent probe

Ni, J.; Cao, B.; Niu, G.; Xu, C.; Ni, Y.

10.1101/2021.03.16.435087 — biophysics — Posted on 2021-03-18

2153 Intertissue mechanical interactions shape the olfactory circuit in zebrafish

Monnot, P.; Gangatharan, G.; Baraban, M.; Pottin, K.; Cabrera, M.; Bonnet, I.; Breau, M. A.

10.1101/2021.03.15.435408 — developmental biology — Posted on 2021-03-18

2154 Widespread premature transcription termination of Arabidopsis thaliana NLR genes by the spen protein FPA

Parker, M. T.; Knop, K.; Zacharaki, V.; Sherwood, A. V.; Tome, D.; Yu, X.; Martin, P.; Beynon, J.; Michaels, S.; Barton, G. J.; Simpson, G. G.

10.1101/2020.12.15.422694 — molecular biology — Posted on 2021-03-18

2155 Extracellular vimentin as a target against SARS- CoV-2 host cell invasion

Suprewicz, L.; Swoger, M.; Gupta, S.; Piktel, E.; Byfield, F. F.; Iwamoto, D. V.; Germann, D. A.; Reszec, J.; Marcinczyk, N.; Carroll, R.; Lenart, M.; Pyrc, K.; Janmey, P. A.; Schwarz, J. M.; Bucki, R.; Patteson, A. E.

10.1101/2021.01.08.425793 — biophysics — Posted on 2021-03-18

2156 Systematic benchmarking of tools for CpG methylation detection from Nanopore sequencing

Yuen, Z. W.-S.; Srivastava, A.; Daniel, R.; McNevin, D.; Jack, C.; Eyras, E.

10.1101/2020.10.14.340315 — bioinformatics — Posted on 2021-03-18

2157 Between virus correlations in the outcome of infection across host species: evidence of virus genotype by host species interactions

Imrie, R.; Roberts, K. E.; Longdon, B.

10.1101/2021.02.16.431403 — evolutionary biology — Posted on 2021-03-18

2158 Neither wood ash application nor phosphorus-fertilisation mitigated the negative effects of whole-tree harvesting on a temperate oligotrophic forest.

Augusto, L.; Beaumont, F.; Nguyen, C.; Fraysse, J.-Y.; Trichet, P.; Meredieu, C.; Vidal, D.; Sappin-Didier, V.

10.1101/2021.03.16.435291 — ecology — Posted on 2021-03-18

2159 Synchronised oscillations in growing cell populations are explained by demographic noise

Gavagnin, E.; Vittadello, S. T.; Gunasingh, G.; Haass, N. K.; Simpson, M. J.; Rogers, T.; Yates, C. A.

10.1101/2020.03.13.987032 — cell biology — Posted on 2021-03-18

2160 Rapid Cortical Adaptation and the Role of Thalamic Synchrony During Wakefulness

Wright, N. C.; Borden, P. Y.; Liew, Y. J.; Bolus, M. F.; Stoy, W. M.; Forest, C. R.; Stanley, G. B.

10.1101/2020.10.08.331660 — neuroscience — Posted on 2021-03-18

2161 The paraventricular thalamus provides a polysynaptic brake on limbic CRF neurons to sex-dependently blunt binge alcohol drinking and avoidance behavior

Levine, O. B.; Skelly, M. J.; Miller, J. D.; Rivera-Irizarry, J. K.; Rowson, S. A.; DiBerto, J. F.; Kash, T. L.; Pleil, K. E.

10.1101/2020.05.04.075051 — neuroscience — Posted on 2021-03-18

2162 In Poetry, if Meter has to Help Memory, it Takes its Time

Andreetta, S.; Soldatkina, O.; Boboeva, V.; Treves, A.

10.1101/2021.03.14.435310 — neuroscience — Posted on 2021-03-18

2163 Dynamics of nonlinguistic statistical learning: From neural entrainment to the emergence of explicit knowledge

Moser, J.; Batterink, L.; Li Hegner, Y.; Schleger, F.; Braun, C.; Paller, K. A.; Preissl, H.

10.1101/2020.07.30.228130 — neuroscience — Posted on 2021-03-18

2164 Real Time Face Recognition with limited training data: Feature Transfer Learning integrating CNN and Sparse Approximation

Bajpai, S.; Mishra, G.

10.1101/2021.03.17.435457 — neuroscience — Posted on 2021-03-18

2165 A comparison of the Mouse Song Analyzer and DeepSqueak ultrasonic vocalization analysis systems in C57BL/6J, FVB.129, and FVB mice

Binder, M. S.; Pranske, Z. P.; Lugo, J. N.

10.1101/2021.03.17.435868 — animal behavior and cognition — Posted on 2021-03-18

2166 Parallel representation of context and multiple context-dependent values in ventro-medial prefrontal cortex

Moneta, N.; Garvert, M. M.; Heekeren, H. R.; Schuck, N. W.

10.1101/2021.03.17.435844 — neuroscience — Posted on 2021-03-18

2167 Deep learning-based pan-cancer classification model reveals cancer-specific gene expression signatures

Divate, M.; Tyagi, A.; Richard, D. J.; Prasad, P. A.; Gowda, H.; H Nagaraj, S.

10.1101/2021.03.15.435283 — bioinformatics — Posted on 2021-03-18

2168 Burrowing crabs and physical factors hasten marsh recovery at panne edges

Beheshti, K.; Endris, C.; Goodwin, P.; Pavlak, A.; Wasson, K.

10.1101/2021.03.17.435836 — ecology — Posted on 2021-03-18

2169 HIV-1 Vpu promotes phagocytosis of infected CD4+ T cells by macrophages through downregulation of CD47

Cong, L.; Sugden, S. M.; Leclair, P.; Lim, C. J.; Pham, T. N.; Cohen, E. A.

10.1101/2021.03.16.435750 — microbiology — Posted on 2021-03-18

2170 Emergence of Probabilistic Representation in the Neural Network of Primary Visual Cortex

Li, A. A.; Wang, F.; Zhang, X.; Wu, S.

10.1101/2021.02.06.429971 — neuroscience — Posted on 2021-03-18

2171 DsbA is a redox-switchable mechanical chaperone

Haldar, S.; Eckels, E. C.; Echelman, D. J.; chaudhuri, d.; chakraborty, s.

10.1101/310169 — biophysics — Posted on 2021-03-18

2172 Coding Recognition of the Dose-Effect Interdependence of Small Biomolecules Encrypted on Paired Chromatographic-Based Microassay Arrays

Deng, Y.; Lin, Z.; Cheng, Y.

10.1101/2021.03.10.434720 — biochemistry — Posted on 2021-03-18

2173 Cryo-EM structure of an elusive pre-transport intermediate of the multidrug transporter BmrCD reveals modes of asymmetric drug binding

Thaker, T. M.; Mishra, S.; Zhou, W.; Faraldo-Gomez, J.; Mchaourab, H.; Tomasiak, T. M.

10.1101/2021.03.13.435271 — biophysics — Posted on 2021-03-17

2174 MLL3/MLL4 Histone Methyltranferase Activity Dependent Chromatin Organization at Enhancers during Embryonic Stem Cell Differentiation

Kubo, N.; Hu, R.; Ye, Z.; Ren, B.

10.1101/2021.03.17.435905 — cell biology — Posted on 2021-03-18

2175 Default Mode Network spatial configuration varies across task domains

Mancuso, L.; Cavuoti-Cabanillas, S.; Liloia, D.; Manuello, J.; Buzi, G.; Duca, S.; Cauda, F.; Costa, T.

10.1101/2021.03.17.435799 — neuroscience — Posted on 2021-03-18

2176 HOXA9 acts as a regulatory switch in acute myeloid leukaemia and myeloproliferative neoplasms

Talarmain, L.; Clarke, M. A.; Shorthouse, D.; Fisher, J.; Hall, B. A.

10.1101/2021.03.05.434116 — cancer biology — Posted on 2021-03-17

2177 A Cdc42-Borg4-Septin 7 axis regulates HSCs polarity and function

Kandi, R.; Senger, K.; Grigoryan, A.; Soller, K.; Sakk, V.; Schuster, T.; Eiwen, K.; Menon, M. B.; Gaestel, M.; Zheng, Y.; Carolina Florian, M.; Geiger, H.

10.1101/2021.03.17.435817 — developmental biology — Posted on 2021-03-17

2178 High prevalence and diversity of beta-lactamase-encoding bacteria in cryosoils and ancient permafrost

Rigou, S.; Christo-Foroux, E.; Santini, S.; Goncharov, A.; Strauss, J.; Grosse, G.; Fedorov, A. N.; Labadie, K.; Abergel, C.; Claverie, J.-M.

10.1101/2021.03.17.435775 — microbiology — Posted on 2021-03-17

2179 Mapping origins of variation in neural trajectories of human pluripotent stem cells

Kim, S. K.; Seo, S.; Stein-O'Brien, G.; Jaishankar, A.; Ogawa, K.; Micali, N.; Wang, Y.; Hyde, T.; Kleinman, J.; Voss, T.; Fertig, E.; Shin, J. H.; Burli, R.; Cross, A. J.; Brandon, N. J.; Weinberger, D. R.; Chenoweth, J. G.; Hoeppner, D. J.; Sestan, N.; Colantuoni, C.; McKay, R. D.

10.1101/2021.03.17.435870 — neuroscience — Posted on 2021-03-17

2180 Genetic diversity and population structure of razor clam Sinonovacula constricta in Ariake Bay, Japan, revealed using RAD-Seq SNP markers.

Orita, R.; Nagano, Y.; Kawamura, Y.; Kimura, K.; Kobayashi, G.

10.1101/2020.10.27.358150 — zoology — Posted on 2021-03-17

2181 Genetically Engineered Strains for Combinatorial Cardiovascular Optobiology

Lee, F. K.; Lee, J. C.; Shui, B.; Reining, S.; Jibilian, M.; Small, D. M.; Jones, J. S.; Allan-Rahill, N. H.; Lamont, M. R.; Rizzo, M. A.; Tajada, S.; Navedo, M. F.; Santana, L. F.; Nishimura, N.; Kotlikoff, M. I.

10.1101/2021.01.21.427692 — physiology — Posted on 2021-03-17

2182 Hydroxycarboxylic acid receptor 2 (HCAR2/GPR109A) expression and signaling promotes the maintenance of an immunoinhibitory retinal environment

Powell, F.; Tawfik, A.; Arjunan, P.; Chopra, D. G.; Al-Shabrawey, M.; Singh, N.; Jadeja, R. N.; Kaufman, M.; Jones, M.; Fromal, O.; Saul, A.; Jahng, W. J.; Bartoli, M.; Martin, P. M.

10.1101/2021.03.15.435493 — biochemistry — Posted on 2021-03-17

2183 Continuous Polony Gels for Tissue Mapping with High Resolution and RNA Capture Efficiency

Fu, X.; Sun, L.; Chen, J.; Dong, R.; Lin, Y.; Palmiter, R.; Lin, S.; Gu, L.

10.1101/2021.03.17.435795 — genomics — Posted on 2021-03-17

2184 Single-cell RNA-seq analysis of human coronary arteries using an enhanced workflow reveals SMC transitions and candidate drug targets

Ma, W. F.; Hodonsky, C. J.; Turner, A. W.; Wong, D.; Song, Y.; Barrientos, N. B.; Verdezoto Mosquera, J.; Miller, C. L.

10.1101/2020.10.27.357715 — genomics — Posted on 2021-03-17

2185 Differences in orthodenticle expression promote ommatidial size variation between Drosophila species

Torres-Oliva, M.; Buchberger, E.; Buffry, A. D.; Kittelmann, M.; Sumner-Rooney, L.; Gaspar, P. M. C.; Bullinger, G. C.; Guerrero, G.; Casares, F.; Arif, S.; Posnien, N.; Nunes, D. D. S.; McGregor, A. P.; Almudi, I.

10.1101/2021.03.17.435774 — evolutionary biology — Posted on 2021-03-17

2186 The transcriptional repressor REST is a major negative regulator of endocrine differentiation during pancreas organogenesis

Rovira, M.; Atla, G.; Maestro, M. A.; Grau, V.; Garcia Hurtado, J.; Maqueda, M.; Mosquera, J. L.; Kerr-Conte, j.; Pattou, F.; Ferrer, J.

10.1101/2021.03.17.435876 — developmental biology — Posted on 2021-03-17

2187 Synonymous Mutation Generator: a web tool for designing RNAi-resistant sequences

Ong, J. Y.

10.1101/2021.01.02.425100 — molecular biology — Posted on 2021-03-17

2188 Synchrony between daily rhythms of malaria parasites and hosts is driven by an essential amino acid

Prior, K. F.; Middleton, B.; Owolabi, A. T.; Westwood, M. L.; Holland, J.; O'Donnell, A. J.; Blackman, M. J.; Skene, D. J.; Reece, S. E.

10.1101/2020.08.24.264689 — microbiology — Posted on 2021-03-17

2189 AC2P20 selectively kills M. tuberculosis at acidic pH by depleting free thiols

Dechow, S. J.; Coulson, G. B.; Wilson, M. W.; Larsen, S. D.; Abramovitch, R. B.

10.1101/2021.03.16.435645 — microbiology — Posted on 2021-03-17

2190 Antibody repertoire analysis of tumor-infiltrating B cells reveals distinct signatures and distributions across tissues

Aizik, L.; Dror, Y.; Taussig, D.; Barzel, A.; Carmi, Y.; Wine, Y.

10.1101/2021.03.17.435773 — immunology — Posted on 2021-03-17

2191 3D models of Alzheimer's disease patient microglia recapitulate disease phenotype and show differential drug responses compared to 2D

Cuni-Lopez, C.; Quek, H.; Oikari, L. E.; Stewart, R.; Nguyen, T. H.; Sun, Y.; Guo, C. C.; Lupton, M. K.; White, A. R.

10.1101/2021.03.17.435758 — neuroscience — Posted on 2021-03-17

2192 The radish Ogura fertility restorer impedes translation elongation along its cognate CMS-causing mRNA

Wang, C.; Lezhneva, L.; Arnal, N.; Quadrado, M.; Mireau, H.

10.1101/2021.03.17.435859 — plant biology — Posted on 2021-03-17

2193 Self-ubiquitination of a pathogen type-III effector traps and blocks the autophagy machinery to promote disease

Leong, J.-X.; Raffeiner, M.; Spinti, D.; Langin, G.; Franz-Wachtel, M.; Guzman, A. R.; Kim, J.-G.; Pandey, P.; Minina, A. E. A.; Macek, B.; Hafren, A.; Bozkurt, T. O.; Mudgett, M. B.; Boernke, F.; Hofius, D.; Uestuen, S.

10.1101/2021.03.17.435853 — plant biology — Posted on 2021-03-17

2194 RABL6A promotes pancreatic neuroendocrine tumor angiogenesis and progression in vivo

Maharjan, C. K.; Kaemmer, C. A.; Muniz, V. P.; Bauchle, C.; Mott, S. L.; Zamba, K. D.; Breheny, P.; Leidinger, M. R.; Darbro, B. W.; Stephens, S.; Meyerholz, D. K.; Quelle, D. E.

10.1101/2021.03.17.435790 — cancer biology — Posted on 2021-03-17

2195 Context dependent isoform specific PI3K inhibition confers drugresistance in Hepatocellular carcinoma cells

Narci, K.; Kahraman, D. C.; Koyas, A.; Ersahin, T.; Tuncbag, N.; Cetin Atalay, R.

10.1101/2021.03.17.435839 — cancer biology — Posted on 2021-03-17

2196 3'-Sulfated Lewis A is a Biomarker for Metaplastic and Oncogenic Transformation of Several Gastrointestinal Epithelia

Brown, J. W.; Das, K. K.; Kalas, V.; Das, K.; Mills, J. C.

10.1101/2021.03.17.435789 — cancer biology — Posted on 2021-03-17

2197 Molecular characterization reveals genomic and transcriptomic subtypes of metastatic urothelial carcinoma

Nakauma-Gonzalez, J. A.; Rijnders, M.; van Riet, J.; van der Heijden, M. S.; Voortman, J.; Cuppen, E. P. J. G.; Mehra, N.; van Wilpe, S.; Oosting, S. F.; Rijstenberg, L. L.; Westgeest, H. M.; Zwarthoff, E.; de Wit, R.; van der Veldt, A. A. M.; van de Werken, H. J. G.; Lolkema, M. P. J.; Boormans, J. L.

10.1101/2021.03.17.435757 — cancer biology — Posted on 2021-03-17

2198 Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumors

Casillas, A. L.; Chauhan, S. S.; Toth, R. K.; Sainz, A. G.; Clements, A. N.; Jensen, C. C.; Langlais, P. R.; Miranti, C. K.; Cress, A. E.; Warfel, N. A.

10.1101/2021.03.17.435865 — cancer biology — Posted on 2021-03-17

2199 Single-stranded nucleic acid sensing and coacervation by linker histone H1

Leicher, R.; Osunsade, A.; Latham, A.; Chua, G. N. L.; Watters, J. W.; Christodoulou-Rubalcava, S.; Zhang, B.; David, Y.; Liu, S.

10.1101/2021.03.17.435841 — biophysics — Posted on 2021-03-17

2200 Structural basis of anti-SARS-CoV-2 activity of hydroxychloroquine: specific binding to NTD/CTD and disruption of LLPS of N protein

Dang, M.; Song, J.

10.1101/2021.03.16.435741 — biophysics — Posted on 2021-03-17

2201 Tree canopy influences ground level atmospheric electrical and biogeochemical variability

Hunting, E.; England, S. J.; Robert, D.

10.1101/2021.03.17.435822 — biophysics — Posted on 2021-03-17

2202 High-content live-cell imaging reveals co-regulation of cardiomyocyte decisions of hypertrophy and apoptosis

Saucerman, J. J.; Chun, B.

10.1101/2021.03.17.435783 — bioinformatics — Posted on 2021-03-17

2203 Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice

Liu, P.; Liang, S.; Zheng, C.; Mintzer, E.; Zhao, Y. G.; Ponnienselvan, K.; Mir, A.; Sontheimer, E. J.; Gao, G.; Flotte, T. R.; Wolfe, S.; Xue, W.

10.1101/2020.12.15.422970 — bioengineering — Posted on 2021-03-17

2204 Gold nanocluster mediated delivery of siRNA to intact plant cells for efficient gene knockdown

Zhang, H.; Cao, Y.; Xu, D.; Goh, N. S.; Demirer, G. S.; Landry, M. P.; Yang, P.

10.1101/2021.03.17.435890 — bioengineering — Posted on 2021-03-17

2205 Lattice micropatterning for cryo-electron tomography studies of cell-cell contacts

Engel, L.; Vasquez, C. G.; Montabana, E. A.; Sow, B. M.; Wakiewicz, M. P.; Weis, W. I.; Dunn, A. R.

10.1101/2020.08.30.272237 — bioengineering — Posted on 2021-03-17

2206 A distinct assembly pathway of the human 39S late pre-mitoribosome

Cheng, J.; Berninghausen, O.; Beckmann, R.

10.1101/2021.03.17.435838 — biochemistry — Posted on 2021-03-17

2207 Testing for evolutionary change in restoration: a genomic comparison between ex situ, native and commercial seed sources of Helianthus maximiliani

Braasch, J.; Di Santo, L.; Tarble, Z.; Prasifka, J.; Hamilton, J.

10.1101/2021.03.17.435854 — genomics — Posted on 2021-03-17

2208 phenopype: a phenotyping pipeline for Python

Luerig, M. D.

10.1101/2021.03.17.435781 — evolutionary biology — Posted on 2021-03-17

2209 The brown algae Saccharina japonica and Sargassum horneri exhibit species-specific responses to synergistic stress of ocean acidification and eutrophication

Liu, Y.; Cao, J.; Chu, Y.; Liu, Y.; Wang, Q.; Gong, Q.; Li, J.

10.1101/2021.03.15.435540 — ecology — Posted on 2021-03-17

2210 The single-cell epigenetic regulatory landscape in mammalian perinatal testis development

Liao, J.; Suen, H. C.; Rao, S.; Luk, A. C. S.; Zhang, R.; Lee, A. W. T.; Chan, T. H. T.; Cheung, M. Y.; Chu, H. T.; So, H. C.; Hobbs, R. M.; Lee, T. L.

10.1101/2021.03.17.435776 — developmental biology — Posted on 2021-03-17

2211 Clathrin adaptors mediate two sequential pathwaysof intra-Golgi recycling

Casler, J. C.; Krahn, A. H.; Pantazopoulou, A.; Johnson, N.; Day, K. J.; Glick, B. S.

10.1101/2021.03.17.435835 — cell biology — Posted on 2021-03-17

2212 A proximity-dependent biotinylation map of a human cell: an interactive web resource

Go, C. D.; Knight, J. D. R.; Rajasekharan, A.; Rathod, B.; Hesketh, G. G.; Abe, K. T.; Youn, J.-Y.; Samavarchi-Tehrani, P.; Zhang, H.; Zhu, L. Y.; Popiel, E.; Lambert, J.-P.; Coyaud, E.; Cheung, S. W. T.; Rajendran, D.; Wong, C. J.; Antonicka, H.; Pelletier, L.; Palazzo, A. F.; Shoubridge, E. A.; Raught, B.; Gingras, A.-C.

10.1101/796391 — molecular biology — Posted on 2021-03-17

2213 De novo transcriptome sequencing of the northern fowl mite, Ornithonyssus sylviarum, shed light into parasitiform poultry mites evolution and its chemoreceptor repertoires

Bhowmick, B.; Chen, H.; Lozano-Fernandez, J.; Vizueta, J.; Ignell, R.; Han, Q.

10.1101/2021.03.17.435780 — molecular biology — Posted on 2021-03-17

2214 Histone sample preparation for bottom-up mass spectrometry: a roadmap to informed decisions

Daled, S.; Willems, S.; Van Puyvelde, B.; Corveleyn, L.; Verhelst, S.; De Clerck, L.; Deforce, D.; Dhaenens, M.

10.1101/2021.03.17.435820 — molecular biology — Posted on 2021-03-17

2215 Epigallocatechin Gallate from Green Tea Effectively Blocks Infection of SARS-CoV-2 and New Variants by Inhibiting Spike Binding to ACE2 Receptor

Liu, J.; Bodnar, B. H.; Meng, F.-Z.; Khan, A.; Wang, X.; Luo, G. G.; Saribas, S.; Wang, T.; Lohani, S. C.; Wang, P.; Wei, Z.; Luo, J.; Zhou, L.; Wu, J.; Li, Q.; Hu, W.; Ho, W.

10.1101/2021.03.17.435637 — microbiology — Posted on 2021-03-17

2216 The transcriptional landscape of Venezuelan equine encephalitis virus (TC-83) infection

Yao, Z.; Zanini, F.; Kumar, S.; Karim, M.; Saul, S.; Bhalla, N.; Panpradist, N.; Muniz, A.; Narayanan, A.; Quake, S. R.; Einav, S.

10.1101/2020.02.18.955393 — microbiology — Posted on 2021-03-17

2217 Sugars dominate the seagrass rhizosphere

Sogin, E. M.; Michellod, D.; Gruber-Vodicka, H.; Bourceau, P.; Geier, B.; Meier, D.; Seidel, M.; Ahmerkamp, S.; Schorn, S.; D'Angelo, G.; Procaccini, G.; Dubilier, N.; Liebeke, M.

10.1101/797522 — microbiology — Posted on 2021-03-17

2218 Synthesis of the NarP response regulator of nitrate respiration in Escherichia coli is regulated at multiple levels by Hfq and small RNAs

Brosse, A.; Walburger, A.; Magalon, A.; Guillier, M.

10.1101/2021.03.17.435884 — microbiology — Posted on 2021-03-17

2219 A squalene-hopene cyclase in Schizosaccharomyces japonicus represents a eukaryotic adaptation to sterol-independent anaerobic growth

Bouwknegt, J.; Wiersma, S. J.; Ortiz-Merino, R. A.; Doornenbal, E. S. R.; Buitenhuis, P.; Giera, M.; Müller, C.; Pronk, J. T.

10.1101/2021.03.17.435848 — microbiology — Posted on 2021-03-17

2220 Global Analysis of the Mammalian MHC class I Immunopeptidome at the Organism-Wide Scale

Kubiniok, P.; Marcu, A.; Bichmann, L.; Kuchenbecker, L.; Schuster, H.; Hamelin, D.; Despault, J.; Kovalchik, K.; Wessling, L.; Kohlbacher, O.; Stevanovic, S.; Hans-Georg, R.; Neidert, M. C.; Sirois, I.; Caron, E.

10.1101/2020.09.28.317750 — immunology — Posted on 2021-03-17

2221 CRISPR-Targeted CAR Gene Insertion Using Cas9/RNP and AAV6 Enhances Anti-AML Activity of Primary NK Cells

Naeimi Kararoudi, M.; Likhite, S.; Elmas, E.; Yamamoto, K.; Schwartz, M.; Sorathia, K.; Pereira, M.; Devine, R.; Lyberger, J.; Behbehani, G. K.; Chakravarti, N.; Moriarity, B. K.; Meyer, K.; Lee, D. A.

10.1101/2021.03.17.435886 — immunology — Posted on 2021-03-17

2222 Dentate spikes and external control of hippocampal function

Dvorak, D.; Chung, A.; Park, E. H.; Fenton, A. A.

10.1101/2020.07.20.211615 — neuroscience — Posted on 2021-03-17

2223 Discrete ripples reflect a spectrum of synchronous spiking activity in human association cortex

Tong, A. P. S.; Vaz, A. P.; Wittig, J. H.; Inati, S. K.; Zaghloul, K. A.

10.1101/2021.03.14.435276 — neuroscience — Posted on 2021-03-17

2224 A conversion from slow to fast memory in response to passive motion

Javidialsaadi, M.; Albert, S. T.; Wang, J.

10.1101/2021.03.09.434594 — neuroscience — Posted on 2021-03-17

2225 Programmable pattern formation in cellular systems with local signaling

Ramalho, T.; Kremser, S.; Wu, H.; Gerland, U.

10.1101/2021.03.17.435764 — synthetic biology — Posted on 2021-03-17

2226 Integration of plant carbohydrate dynamics by Fourier polynomials

Seydel, C.; Biener, J.; Brodsky, V.; Eberlein, S.; Naegele, T.

10.1101/2021.03.16.435635 — plant biology — Posted on 2021-03-17

2227 Membrane Hydrophobicity Determines the Activation Free Energy of Passive Lipid Transport

Rogers, J. R.; Espinoza Garcia, G.; Geissler, P. L.

10.1101/2021.03.17.435885 — biophysics — Posted on 2021-03-17

2228 Co-condensation of proteins with single- and double-stranded DNA

Renger, R.; Morin, J. A.; Lemaitre, R.; Ruer, M.; Julicher, F.; Hermann, A.; Grill, S. W.

10.1101/2021.03.17.435834 — biophysics — Posted on 2021-03-17

2229 A Comparative Analysis of Novel Deep Learning and Ensemble Learning Models to Predict the Allergenicity of Food Proteins

Wang, L.; Niu, D.; Zhao, X.; Wang, X.; Hao, M.; Che, H.

10.1101/2021.03.10.434710 — bioinformatics — Posted on 2021-03-17

2230 A Hierarchical 3D-motion Learning Framework for Animal Spontaneous Behavior Mapping

Huang, K.; Han, Y.; Chen, K.; Pan, H.; Zhao, G.; Yi, W.; Li, X.; Liu, S.; Wang, L.; Wei, P.

10.1101/2020.09.14.295808 — animal behavior and cognition — Posted on 2021-03-17

2231 4polar-STORM polarized super-resolution imaging of actin filament organization in cells

Rimoli, C. V.; Valades Cruz, C. A.; Curcio, V.; Mavrakis, M.; Brasselet, S.

10.1101/2021.03.17.435879 — biophysics — Posted on 2021-03-17

2232 iPSC-derived pancreatic progenitors are an optimal model system to study T2D regulatory variants active during fetal development of the pancreas

D'Antonio-Chronowska, A.; Donovan, M. K. R.; Fujita, K.; Salgado, B. M.; Matsui, H.; Arthur, T. D.; Nguyen, J. P.; D'Antonio, M.; Frazer, K. A.

10.1101/2021.03.17.435846 — genomics — Posted on 2021-03-17

2233 Mitochondrial fission is required for proper nucleoid distribution within mitochondrial networks

Ilamathi, H. S.; Ouellet, M.; Sabouny, R.; Desrochers-Goyette, J.; Lines, M. A.; Pfeffer, G.; SHUTT, T. E.; Germain, M.

10.1101/2021.03.17.435804 — cell biology — Posted on 2021-03-17

2234 Transcriptome analysis of the NR1H3 mouse model of multiple sclerosis reveals a pro-inflammatory phenotype with dysregulation of lipid metabolism and immune response genes

Vilarino-Guell, C.; Encarnacion, M.; Bernales, C. Q.; Kamma, E.; Becquart, P.; Quandt, J. A.

10.1101/2021.03.17.435678 — molecular biology — Posted on 2021-03-17

2235 Disruption of origin chromatin structure by helicase activation in the absence of DNA replication

Hoffman, R. A.; MacAlpine, D. M.

10.1101/2021.03.17.435814 — molecular biology — Posted on 2021-03-17

2236 Subnuclear localisation is associated with gene activation not repression or parental origin at the imprinted Dlk1-Dio3 locus

Mashoodh, R.; Hulsmann, L. C.; Dearden, F. L.; Takahashi, N.; Ferguson-Smith, A. C.

10.1101/2021.03.17.435843 — molecular biology — Posted on 2021-03-17

2237 Longitudinal characterization of humoral and cellular immunity in hospitalized COVID-19 patients reveal immune persistence up to 9 months after infection

Sandberg, J. T.; Varnaite, R.; Christ, W.; Chen, P.; Muvva, J. R.; Maleki, K. T.; Garcia, M.; Dzidic, M.; Folkesson, E.; Skagerberg, M.; Ahlen, G.; Frelin, L.; Sällberg, M.; The Karolinska COVID-19 Study Group, ; Eriksson, L. I.; Rooyackers, O.; Sönnerborg, A.; Buggert, M.; Björkström, N. K.; Aleman, S.; Stralin, K.; Klingström, J.; Ljunggren, H.-G.; Blom, K.; Gredmark-Russ, S.

10.1101/2021.03.17.435581 — immunology — Posted on 2021-03-17

2238 SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway

Khan, S.; Shafiei, M. S.; Longoria, C.; Schoggins, J.; Savani, R. C.; Zaki, H.

10.1101/2021.03.16.435700 — immunology — Posted on 2021-03-17

2239 SARS-CoV-2 Spike receptor-binding domain with a G485R mutation in complex with human ACE2

Weekley, C. M.; Purcell, D. F. J.; Parker, M. W.

10.1101/2021.03.16.434488 — biochemistry — Posted on 2021-03-17

2240 Identification of ACE2 mutations that modulate SARS-CoV-2 spike binding across multiple mammalian species

Heinzelman, P.; Romero, P. A.

10.1101/2021.03.16.435705 — biochemistry — Posted on 2021-03-17

2241 Characterisation of a novel ACE2-based therapeutic with enhanced rather than reduced activity against SARS-CoV2 variants

Ferrari, M.; Mekkaoui, L.; Ilca, F. T.; Akbar, Z.; Bughda, R.; Lamb, K.; Ward, K.; Parekh, F.; Karattil, R.; Allen, C.; Wu, P.; Baldan, V.; Mattiuzzo, G.; Bentley, E. M.; Takeuchi, Y.; Sillibourne, J.; Datta, P.; Kinna, A.; Pule, M.; Onuoha, S.

10.1101/2021.03.17.435802 — immunology — Posted on 2021-03-17

Hur, J.; Kuhn, M.; Grogans, S. E.; Anderson, A. S.; Islam, S.; Kim, H. C.; Tillman, R. M.; Fox, A. S.; Smith, J. F.; DeYoung, K. A.; Shackman, A. J.

10.1101/2021.03.17.435791 — neuroscience — Posted on 2021-03-17

2243 Changing in the hierarchical organization of local information dynamics during motor decision in the premotor cortex of primates

Bardella, G.; Giarrocco, F.; Andujar, M.; Brunamonti, E.; Pani, P.; Ferraina, S.

10.1101/2021.03.15.435381 — neuroscience — Posted on 2021-03-17

2244 Multiple dimensions of social motivation in adult female degus

Lidhar, N. K.; Thakur, A.; David, A.-J.; Takehara-Nishiuchi, K.; Insel, N.

10.1101/2020.07.07.191486 — animal behavior and cognition — Posted on 2021-03-17

2245 When is it Worth Working for Water? A Utility Maximization Theory

Reinagel, P.

10.1101/2021.03.01.433467 — animal behavior and cognition — Posted on 2021-03-17

2246 Early-Emerging and Highly-Heritable Sensitivity to Human Communication in Dogs

Bray, E. E.; Gnanadesikan, G. E.; Horschler, D. J.; Levy, K. M.; Kennedy, B. S.; Famula, T. R.; MacLean, E. L.

10.1101/2021.03.17.434752 — animal behavior and cognition — Posted on 2021-03-17

2247 Lichen fungi do not depend on the alga for ATP production

Tagirdzhanova, G.; McCutcheon, J.; Spribille, T.

10.1101/2021.03.17.435722 — genomics — Posted on 2021-03-17

2248 Phylotranscriptomics points to multiple independent origins of multicellularity and cellular differentiation in the volvocine algae

Lindsey, C. R.; Rosenzweig, F.; Herron, M. D.

10.1101/2021.03.16.435725 — evolutionary biology — Posted on 2021-03-17

2249 Ecological differentiation and incipient speciation in the fungal pathogen causing rice blast

Thierry, M.; Charriat, F.; Milazzo, J.; Adreit, H.; Ravel, S.; Borron, S.; Sella, V.; Kroj, T.; Ioos, R.; Fournier, E.; Tharreau, D.; Gladieux, P.

10.1101/2020.06.02.129296 — evolutionary biology — Posted on 2021-03-17

2250 Quantifying the dynamics of viral recombination during free virus and cell-to-cell transmission in HIV-1 infection

Kreger, J.; Garcia, J.; Zhang, H.; Komarova, N. L.; Wodarz, D.; Levy, D. N.

10.1101/2020.08.28.272351 — evolutionary biology — Posted on 2021-03-17

2251 Estimating occupancy dynamics and encounter rates with species misclassification: a semi-supervised individual-level approach

Spiers, A. I.; Royle, J. A.; Torrens, C. L.; Joseph, M. B.

10.1101/2021.03.17.433917 — ecology — Posted on 2021-03-17

2252 Function of the Vibrio PomB plug region based on the stator rotation model for bacterial flagellar motor

Homma, M.; Terashima, H.; Koiwa, H.; Kojima, S.

10.1101/2021.03.16.435749 — microbiology — Posted on 2021-03-17

2253 The discovery, distribution and diversity of DNA viruses associated with Drosophila melanogaster in Europe

Wallace, M. A.; Coffman, K. A.; Gilbert, C.; Ravindran, S.; Albery, G. F.; Abbott, J.; Argyridou, E.; Bellosta, P.; Betancourt, A. J.; Colinet, H.; Eric, K.; Glaser-Schmitt, A.; Grath, S.; Jelic, M.; Kankare, M.; Kozeretska, I.; Loeschcke, V.; Montchamp-Moreau, C.; Ometto, L.; Onder, B. S.; Orengo, D. J.; Parsch, J.; Pascual, M.; Patenkovic, A.; Puerma, E.; Ritchie, M. G.; Rota-Stabelli, O.; Schou, M. F.; Serga, S. V.; Stamenkovic-Radak, M.; Tanaskovic, M.; Veselinovic, M. S.; Vieira, J.; Vieira, C. P.; Kapun, M.; Flatt, T.; Gonzalez, J.; Staubach, F.; Obbard, D. J.

10.1101/2020.10.16.342956 — microbiology — Posted on 2021-03-17

2254 An inconvenient association between granzyme A and Nicotinamide Nucleotide Transhydrogenase

Rawle, D. J.; Le, T.; Dumenil, T.; Bishop, C.; Yan, K.; Nakayama, E.; Bird, P. I.; Suhrbier, A.

10.1101/2021.03.16.435730 — immunology — Posted on 2021-03-17

2255 Mechanisms underlying vaccination protocols that may optimally elicit broadly neutralizing antibodies against highly mutable pathogens

Ganti, R. S.; Chakraborty, A. K.

10.1101/2020.10.07.330340 — immunology — Posted on 2021-03-17

2256 Real Time Face Recognition with limited training data: Feature Transfer Learning integrating CNN and Sparse Approximation

Mishra, G.; Bajpai, S.

10.1101/2021.03.17.435457 — neuroscience — Posted on 2021-03-17

2257 Implementation and acceleration of optimal control for systems biology

Sharp, J. A.; Burrage, K.; Simpson, M. J.

10.1101/2021.03.17.435721 — systems biology — Posted on 2021-03-17

2258 Understanding C4 photosynthesis in Setaria by a proteomic and kinetic approach

Calace, P.; Tonetti, T.; Margarit, E.; Figueroa, C. M.; Lobertti, C.; Andreo, C. S.; Gerrard Wheeler, M. C.; Saigo, M.

10.1101/2021.03.16.435684 — plant biology — Posted on 2021-03-17

2259 Wheels within wheels, Nested Function-value Traits as a Tool for Modeling Ontogeny

Hodge, J. G.; Doust, A.

10.1101/2021.03.16.435729 — plant biology — Posted on 2021-03-17

2260 Dynamic plasticity within the EMT spectrum, rather than static mesenchymal traits, drives tumor heterogeneity and metastatic progression of breast cancers

Brown, M. S.; Abdollahi, B.; Wilkins, O. M.; Chakraborty, P.; Ognjenovic, N. B.; Muller, K. E.; Jolly, M. K.; Hassanpour, S.; Pattabiraman, D. R.

10.1101/2021.03.17.434993 — cancer biology — Posted on 2021-03-17

2261 Network analysis reveals different strategies of Trichoderma spp. associated with XYR1 and CRE1 during cellulose degradation

Rosolen, R. R.; Aono, A. H.; Almeida, D. A.; Filho, J. A. F.; Horta, M. A. C.; de Souza, A. P.

10.1101/2020.05.02.074344 — bioinformatics — Posted on 2021-03-17

2262 Discovery of TMPRSS2 inhibitors from virtual screening

Hu, X.; Shrimp, J. H.; Guo, H.; Xu, M.; Chen, C. Z.; Zhu, W.; Zakharov, A. V.; Jain, S.; Shinn, P.; Simeonov, A.; Hall, M.; Shen, M.

10.1101/2020.12.28.424413 — bioinformatics — Posted on 2021-03-17

2263 Identification of a High-frequency Intra-host SARS-CoV-2 spike Variant with Enhanced Cytopathic and Fusogenic Effect

Rocheleau, L.; Laroche, G.; Fu, K.; Stewart, C. M.; Mohamud, A. O.; Cote, M.; Giguere, P. M.; Langlois, M.-A.; Pelchat, M.

10.1101/2020.12.03.409714 — bioinformatics — Posted on 2021-03-17

2264 The unphosphorylated form of the PAQosome core subunit RPAP3 binds ribosomal preassembly complexes to modulate ribosome biogenesis.

Pinard, M.; Cloutier, P.; Poitras, C.; Gauthier, M.-S.; Coulombe, B.

10.1101/2021.03.17.435124 — biochemistry — Posted on 2021-03-17

2265 Genome sequencing and morphometric analysis of alpine bumblebees experiencing climate change reveal ongoing phenotypic shifts and a lack of population structure

Christmas, M. J.; Jones, J. C.; Olsson, A.; Wallerman, O.; Bunikis, I.; Kierczak, M.; Whitley, K. M.; Sullivan, I.; Geib, J. C.; Miller-Struttmann, N. E.; Webster, M. T.

10.1101/2021.03.17.435598 — evolutionary biology — Posted on 2021-03-17

2266 Cortex cis-regulatory switches establish scale colour identity and pattern diversity in Heliconius

Livraghi, L.; Hanly, J. J.; Van Belleghem, S. M.; Montejo-Kovacevich, G.; van der Heijden, E. S. M.; Loh, L. S.; Ren, A.; Warren, I. A.; Lewis, J. J.; Concha, C.; Lopez, L. H.; Wright, C.; Walker, J. M.; Goldberg, Z. H.; Foley, J.; Arenas-Castro, H.; Perry, M. W.; Papa, R.; Martin, A.; McMillan, W. O.; Jiggins, C. D.

10.1101/2020.05.26.116533 — evolutionary biology — Posted on 2021-03-17

2267 Dissecting the roles of MBD2 isoforms in regulating NuRD complex function during cellular differentiation

Schmolka, N.; Bhaskaran, J.; Karemaker, I. D.; Baubec, T.

10.1101/2021.03.17.435677 — molecular biology — Posted on 2021-03-17

2268 Strong genetic structure and limited connectivity among populations of Clark's Anemonefish (Amphiprion clarkii) in the centre of marine biodiversity

Ducret, H.; Timm, J.; Rodriguez Moreno, M.; Huyghe, F.; Kochzius, M.

10.1101/2021.03.17.433695 — molecular biology — Posted on 2021-03-17

2269 Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope

Abernathy, M. E.; Gristick, H. B.; Vielmetter, J.; Keeffe, J. R.; Gnanapragasam, P. N.; Lee, Y. E.; Escolano, A.; Gautam, R.; Seaman, M. S.; Martin, M. A.; Nussenzweig, M. C.; Bjorkman, P. J.

10.1101/2021.03.17.435265 — immunology — Posted on 2021-03-17

2270 GABAergic neuronal IL-4R mediates T cell effect on memory

Kipnis, J.; Fu, Z.; Dykstra, T.; Li, H.; Salvador, A.; Zou, B.; Yan, N.; Andrews, P.; Papadopoulos, Z.; Smirnov, I.; Xie, X.; Herz, J.

10.1101/2021.03.16.435727 — neuroscience — Posted on 2021-03-17

2271 An optimal population code for global motion estimation in local direction-selective cells

Henning, M.; Ramos-Traslosheros, G.; Gür, B.; Silies, M.

10.1101/2021.03.17.435642 — neuroscience — Posted on 2021-03-17

2272 Stable brain PET metabolic networks using a multiple sampling scheme

Schu, G.; Brum, W. S.; Rodrigues, Y. E.; de Azeredo, J. C.; Pascoal, T. A.; Benedet, A. L.; Mathotaarachchi, S.; Rosa-Neto, P.; Almeida, J.; Zimmer, E. R.

10.1101/2021.03.16.435674 — neuroscience — Posted on 2021-03-17

2273 Neural correlates of metacognition across the adult lifespan

Overhoff, H.; Ko, Y. H.; Feuerriegel, D.; Fink, G. R.; Stahl, J.; Weiss, P. H.; Bode, S.; Niessen, E.

10.1101/2021.03.17.431767 — neuroscience — Posted on 2021-03-17

2274 Case study of a rhizosphere microbiome assay on a bamboo rhizome with excessive shoots

Cui, F.; Yang, Y.; Ye, M.; Wei, W.; Huang, W.; Wu, Y.; Xi, J.; Ye, X.; Zhou, S.; Hu, Z.; Gui, R.; Wu, W.; Yrjala, K.; Overmyer, K.; Liu, S.

10.1101/2021.03.16.435735 — plant biology — Posted on 2021-03-17

2275 Manganese toxicity disrupts indole acetic acid homeostasis and suppresses CO2 assimilation reaction in rice plants

Takagi, D.; Ishiyama, K.; Suganami, M.; Ushijima, T.; Fujii, T.; Tazoe, Y.; Kawasaki, M.; Noguchi, K.; Makino, A.

10.1101/2021.03.16.435720 — plant biology — Posted on 2021-03-17

2276 Characterizing Locus Specific Chromatin Structure and Dynamics with Correlative Conventional and Super Resolution imaging in living cells

Mehra, D.; Adhikari, S.; Banerjee, C.; Puchner, E. M.

10.1101/2021.03.16.435731 — biophysics — Posted on 2021-03-17

2277 Structural analysis of the OC43 coronavirus 2'-O-RNA methyltransferase

Dostalik, P.; Krafcikova, P.; Silhan, J.; Boura, E.

10.1101/2021.03.16.435745 — biophysics — Posted on 2021-03-17

2278 Single-cell RNA-seq revealed the role of Alkbh5 in reproduction

Shen, X.; Xie, G.

10.1101/2021.03.06.434224 — bioinformatics — Posted on 2021-03-17

2279 GdDO3NI allows imaging of hypoxia after brain injury

Moghadas, B.; Bharadwaj, V. N.; Tobey, J. P.; Tian, Y.; Stabenfeldt, S. E.; Kodibagkar, V. D.

10.1101/2021.03.16.435723 — bioengineering — Posted on 2021-03-17

2280 The Burden Borne by Protein Methyltransferases: Rates and Equilibria of Nonenzymatic Methylation of Amino Acid Side-Chains by SAM in Water

Wolfenden, R.; Lewis, C. A.

10.1101/2021.03.17.435195 — biochemistry — Posted on 2021-03-17

2281 Beyond single discrete responses: An integrative and multidimensional analysis of behavioral dynamics assisted by Machine Learning

Leon, A.; Hernandez, V.; Lopez, J.; Guzman, I.; Quintero, V.; Toledo, P.; Avendano-Garrido, M. L.; Hernandez-Linares, C.; Escamilla, E.

10.1101/2021.03.17.435751 — animal behavior and cognition — Posted on 2021-03-17

2282 Identification of anthracnose (Colletotrichum lentis) race 1 resistance loci in lentil by integrating linkage mapping and a genome-wide association study

Gela, T. S.; Ramsay, L.; Haile, T.; Vandenberg, A.; Bett, K.

10.1101/2021.03.16.435724 — genomics — Posted on 2021-03-17

2283 Meiotic Cas9 expression mediates genotype conversion in the male and female mouse germline

Weitzel, A. J.; Grunwald, H. A.; Levina, R.; Gantz, V. M.; Hedrick, S. M.; Bier, E.; Cooper, K. L.

10.1101/2021.03.16.435716 — genetics — Posted on 2021-03-17

2284 The mayfly subimago explained. The regulation of metamorphosis in Ephemeroptera

Kamsoi, O.; Ventos-Alfonso, A.; Almudi, I.; Casares, F.; Belles, X.

10.1101/2021.03.17.435759 — evolutionary biology — Posted on 2021-03-17

2285 A Phytosociological Classification Of The Peruvian Vegetation

Galan de Mera, A.; Campos de la Cruz, J.; Linares Perea, E.; Montoya Quino, J.; Torres Marquina, I.; Vicente Orellana, J. A.

10.1101/2021.03.17.435755 — ecology — Posted on 2021-03-17

2286 Investigating temperature effects on coastal microbial populations and trophic interactions with 16S and 18S rRNA metabarcoding

Anderson, S. R.; Harvey, E. L.; Chisholm, M.

10.1101/2021.03.17.435717 — ecology — Posted on 2021-03-17

2287 The Fragile X Mental Retardation Protein protects the lung from xenobiotic stress by facilitating the Integrated Stress Response

Sain Basu, D.; Bhavsar, R.; Gulami, I.; Lingamallu, S.; Muddashetty, R.; Veeranna, C.; Chattarji, S.; Thimmulappa, R.; Bhattacharya, A.; Guha, A.

10.1101/2021.03.16.435743 — cell biology — Posted on 2021-03-17

2288 Whats under the Christmas tree? Soil acidification alters fir tree rhizosphere bacterial and eukaryotic communities, their interactions, and functional traits

Steven, B.; La Reau, J. C.; Taerum, S. J.; Zuverza-Mena, N.; Cowles, R. S.

10.1101/2021.03.16.435746 — microbiology — Posted on 2021-03-17

2289 Tumor-reactivity of d2 negative gdT cells and the role of the gdT cell receptor

van Dooremalen, S.; Janssen, A.; Bloemenkamp, L.; Yonka, A.; Beringer, D.; Kuball, J.

10.1101/2021.03.17.435293 — immunology — Posted on 2021-03-17

2290 Spinal sensory neurons project onto hindbrain to stabilize posture and enhance locomotor speed

Wu, M. Y.; CARBO TANO, M.; Mirat, O.; Lejeune, F.-X.; Roussel, J.; Quan, F.; Fidelin, K.; Wyart, C.

10.1101/2021.03.16.435696 — neuroscience — Posted on 2021-03-17

2291 Cyto/myeloarchitectural changes of cortical gray matter and superficial white matter in early neurodevelopment: Multimodal MRI study of preterm neonates

Yuan, S.; Liu, M.; Kim, S.; Yang, J.; Barkovich, A. J.; Xu, D.; Kim, H.

10.1101/2021.03.16.435692 — neuroscience — Posted on 2021-03-17

2292 Identification and drug-induced reversion of molecular signatures of Alzheimers disease onset and progression in AppNL-G-F, AppNL-F and 3xTg-AD mouse models

Pauls, E.; Bayod, S.; Mateo, L.; Alcalde, V.; Juan-Blanco, T.; Saido, T. C.; Saito, T.; Berenguer-Llergo, A.; Stephan-Otto Attolini, C.; Gay, M.; de Oliveira, E.; Duran-Frigola, M.; Aloy, P.

10.1101/2021.03.17.435753 — neuroscience — Posted on 2021-03-17

2293 Characterization of an Agarophyton chilense oleoresin containing PPARγ natural ligands with insulin-sensitizing effects in a C57BL/6J mouse model of diet-induced obesity and antioxidant activity in Caenorhabditis elegans.

Pinto, C.; Ibanez, M. R.; Loyola, G.; Leon, L.; Salvatore, Y.; Gonzalez, C.; Barraza, V.; Castaneda, F.; Aldunate, R.; Contreras-Porcia, L.; Fuenzalida, K.; Bronfman, F. C.

10.1101/2021.03.16.435726 — physiology — Posted on 2021-03-17

2294 Actin filament alignment causes mechanical hysteresis in cross-linked networks

Scheff, D. R.; Redford, S. A.; Lorpaiboon, C.; Majumdar, S.; Dinner, A. R.; Gardel, M. L.

10.1101/2021.03.16.435707 — biophysics — Posted on 2021-03-17

2295 RCytoGPS: An R Package for Reading and Visualizing Cytogenetics Data

Abrams, Z. B.; Tally, D. G.; Abruzzo, L. V.; Coombes, K. R.

10.1101/2021.03.16.389791 — bioinformatics — Posted on 2021-03-17

2296 Computational Evaluation of DNA Metabarcoding for Universal Diagnostics of Invasive Insect Pests

Piper, A. M.; Cogan, N. O. I.; Cunningham, J. P.; Blacket, M. J.

10.1101/2021.03.16.435710 — bioinformatics — Posted on 2021-03-17

2297 Enhancing Drug-Drug Interaction Prediction Using Deep Attention Neural Networks

Liu, S.; Zhang, Y.; Cui, Y.; Qiu, Y.; Deng, Y.; Zhang, W.; Zhang, Z.

10.1101/2021.03.16.435553 — bioinformatics — Posted on 2021-03-17

2298 Modelling Human Gait using a Nonlinear Differential Equation

Schmalz, J.; Paul, D.; Shorter, K.; Cooper, M.; Murphy, A.

10.1101/2021.03.16.435713 — bioengineering — Posted on 2021-03-17

2299 Alginate-based microparticles coated with HPMCP/AS cellulose-derivatives enable the Ctx(Ile21)-Ha antimicrobial peptide application as a feed additive

Roque Borda, C. A.; Leite Silva, H. R.; Crusca Junior, E.; Serafim, J. A.; Meneguin, A. B.; Chorilli, M.; Costa Macedo, W.; Rainho Teixeira, S.; Lopes Guastalli, E. A.; Soares, N. M.; Blair, J. M.; Pikramenou, Z.; Vicente, E. F.

10.1101/2021.03.16.435719 — biochemistry — Posted on 2021-03-17

2300 Topography-dependent gene expression and function of common cell archetypes in large and small porcine airways

Pezzulo, A. A.; Thurman, A. L.; Li, X.; Villacreses, R.; Yu, W.; Mather, S. E.; Romano-Ibarra, G. S.; Meyerholz, D. K.; Stoltz, D. A.; Welsh, M. J.; Thornell, I. M.; Zabner, J.

10.1101/2021.03.16.435690 — genomics — Posted on 2021-03-17

2301 Genome-wide DNA methylation and transcriptome integration reveal distinct sex differences in skeletal muscle.

Landen, S.; Jacques, M.; Hiam, D.; Romero, J. A.; Harvey, N. R.; Haupt, L. M.; Griffiths, L. R.; Ashton, K. J.; Lamon, S.; Voisin, S.; Eynon, N.

10.1101/2021.03.16.435733 — genomics — Posted on 2021-03-17

2302 Neither wood ash application nor phosphorus-fertilisation mitigated the negative effects of whole-tree harvesting on a temperate oligotrophic forest.

Augusto, L.; Beaumont, F.; Nguyen, C.; Fraysse, J.-Y.; Trichet, P.; Meredieu, C.; Vidal, D.; Sappin-Didier, V.

10.1101/2021.03.16.435291 — ecology — Posted on 2021-03-17

2303 A millennium of increasing ecosystem diversity until the mid-20th century

Martins, I. S.; Dornelas, M.; Vellend, M.; Thomas, C. D.

10.1101/2021.03.16.435590 — ecology — Posted on 2021-03-17

2304 Efficacy of two commercial disinfectants on Paenibacillus larvae spores

Kiriamburi, J.; Nilsson, A.; Muturi, J.; Mugweru, J.; Forsgren, E.

10.1101/2021.03.16.435711 — microbiology — Posted on 2021-03-17

2305 Collagen density defines 3D migration of CTLs and their consequent cytotoxicity against tumor cells

Zhao, R.; Zhou, X.; Khan, E. S.; Alansary, D.; Friedmann, K. S.; Yang, W.; Schwarz, E. C.; del Campo, A.; Hoth, M.; Qu, B.

10.1101/2021.03.16.435689 — immunology — Posted on 2021-03-17

2306 B cells imprint adoptively transferred CD8+ T cells with enhanced tumor immunity

Smith, A. S.; Knochelmann, H. M.; Wyatt, M. M.; Rangel Rivera, G. O.; Rivera-Reyes, A. M.; Dwyer, C. J.; Neskey, D. M.; Rubinstein, M. P.; Liu, B.; Thaxton, J. E.; Bartee, E.; Paulos, C. M.

10.1101/2021.03.16.435714 — immunology — Posted on 2021-03-17

2307 Adolescent Stress Confers Resilience to Traumatic Stress Later in Life: Role of the Prefrontal Cortex

Cotella, E.; Nawreen, N.; Moloney, R.; Martelle, S.; Oshima, K.; Lemen, P.; NiBlack, J.; Julakanti, R.; Fitzgerald, M.; Baccei, M.; Herman, J.

10.1101/2021.03.16.435691 — neuroscience — Posted on 2021-03-17

2308 Sex-specific, pdfr-1-dependent modulation of pheromone avoidance by food abundance enables flexibility in C. elegans foraging behavior

Luo, J.; Portman, D. S.

10.1101/2021.03.16.435685 — neuroscience — Posted on 2021-03-17

2309 Sex-specific interactions between procedural and deliberative decision-making systems in a mouse model of Alzheimer's disease

Anderson, R.; Hart, D. W.; Sweis, B.; Sherman, M. A.; Thomas, M.; Redish, D. D.; Lesne, S.

10.1101/2021.03.16.435712 — neuroscience — Posted on 2021-03-17

2310 L-Thyroxine improves vestibular compensation in a rat model of acute peripheral vestibulopathy

Rastoldo, G.; Marouane, E.; El-Mahmoudi, N.; Pericat, D.; Watabe, I.; Lapotre, A.; Tonetto, A.; Lopez-Juarez, A.; Caron, P.; Fraysse, M.-J. E.; Zwergal, A.; Tighilet, B.

10.1101/2021.03.16.435610 — neuroscience — Posted on 2021-03-17

2311 Growth-Rate Dependent And Nutrient-Specific Gene Expression Resource Allocation In Fission Yeast

Kleijn, I. T.; Martinez-Segura, A.; Bertaux, F.; Saint, M.; Kramer, H.; Shahrezaei, V.; Marguerat, S.

10.1101/2021.03.16.435638 — systems biology — Posted on 2021-03-17

2312 OCRbayes: A Bayesian hierarchical modeling framework for Seahorse extracellular flux oxygen consumption rate data analysis

Zhang, X.; Yuan, T.; Keijer, J.; de Boer, V. C. J.

10.1101/2021.03.16.435639 — systems biology — Posted on 2021-03-17

2313 Binary Interactome Models of Inner- Versus Outer-Complexome Organization

Lambourne, L.; Yadav, A.; Wang, Y.; Desbuleux, A.; Kim, D.-K.; Cafarelli, T.; Pons, C.; Kovacs, I. A.; Jailkhani, N.; Schlabach, S.; De Ridder, D.; Luck, K.; Bian, W.; Shen, Y.; Mee, M.; Jacob, Y.; Lemmens, I.; Rolland, T.; Tavernier, J.; Spirohn, K.; Zhong, Q.; Aloy, P.; Hao, T.; Charloteaux, B.; Roth, F. P.; Hill, D. E.; Calderwood, M. A.; Twizere, J.-C.; Vidal, M.

10.1101/2021.03.16.435663 — systems biology — Posted on 2021-03-17

2314 Precise measurements of chromatin diffusion dynamics by modeling using Gaussian processes

Oliveira, G. M.; Oravecz, A.; Kobi, D.; Maroquenne, M.; Bystricky, K.; Sexton, T.; Molina, N.

10.1101/2021.03.16.435699 — systems biology — Posted on 2021-03-17

2315 DeepCob: Precise and high-throughput analysis of maize cob geometry using deep learning with an application in genebank phenomics

Kienbaum, L.; Correa Abondano, M.; Blas Sevillano, R. H.; Schmid, K. J.

10.1101/2021.03.16.435660 — plant biology — Posted on 2021-03-17

2316 The Arabidopsis ORA59 coordinates jasmonic acid- and ethylene-responsive gene expression to regulate plant immunity

Yang, Y. N.; Kim, Y.; Kim, H.; Kim, S. J.; Cho, K.-M.; Kim, Y.; Lee, D. S.; Lee, M.-H.; Kim, S. Y.; Hong, J. C.; Kwon, S. J.; Choi, J.; Park, O. K.

10.1101/2021.03.16.435681 — plant biology — Posted on 2021-03-17

2317 The interplay of chromatin phase separation and lamina interactions in nuclear organisation

Laghmach, R.; Di Pierro, M.; Potoyan, D. A.

10.1101/2021.03.16.435657 — biophysics — Posted on 2021-03-17

2318 GlucoCEST MRI for the early evaluation response to chemotherapeutic and metabolic treatments in a murine triple negative breast cancer: a comparison with 18F-FDG-PET.

Capozza, M.; Anemone, A. A.; Dhakan, C.; Della Peruta, M.; Bracesco, M.; Zullino, S.; Villano, D.; Terreno, E.; Longo, D. L.; Aime, S.

10.1101/2021.03.16.432430 — biophysics — Posted on 2021-03-17

2319 BugSeq 16S: NanoCLUST with Improved Consensus Sequence Classification

Jung, A.; Chorlton, S. D.

10.1101/2021.03.16.434153 — bioinformatics — Posted on 2021-03-17

2320 A novel, open source, low-cost bioreactor for load-controlled cyclic loading of tendon explants

Pedaprolu, K.; Szczesny, S.

10.1101/2021.03.16.435688 — bioengineering — Posted on 2021-03-17

2321 FastTomo: A SerialEM Script for Collecting Electron Tomography Data

Xu, A.; Xu, C.

10.1101/2021.03.16.435675 — bioengineering — Posted on 2021-03-17

2322 Cis-regulatory variants affect gene expression dynamics in yeast

Shih, C.-H.; Fay, J. C.

10.1101/2021.03.16.435665 — evolutionary biology — Posted on 2021-03-17

2323 Timing of increased temperature sensitivity coincides with nervous system development in winter moth embryos

van Dis, N. E.; van der Zee, M.; Hut, R. A.; Wertheim, B.; Visser, M. E.

10.1101/2021.03.16.435649 — evolutionary biology — Posted on 2021-03-17

2324 Cellular pathways during spawning induction in the starlet sea anemone Nematostella vectensis

Reuven, S.; Rinsky, M.; Brekhman, V.; Malik, A.; Levy, O.; Lotan, T.

10.1101/2021.03.16.435650 — ecology — Posted on 2021-03-17

2325 Male rat sexual behavior: insights from inter-copulatory intervals

Huijgens, P. T.; Guarraci, F. G.; Olivier, J. D. A.; Snoeren, E. M. S.

10.1101/2021.03.16.435659 — neuroscience — Posted on 2021-03-17

2326 Cannabidiol attenuates cognitive deficits and neuroinflammation induced by early alcohol exposure in a mice model.

Puig, X. R.; Algar, O. G.; Valverde, O.; Baos, A. G.

10.1101/2021.03.16.435465 — neuroscience — Posted on 2021-03-17

2327 MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior

Toledo, A.; Bimbi, G.; Letellier, M.; Tessier, B.; Daburon, S.; Favereaux, A.; Chamma, I.; Vennekens, K.; Vanderlinden, J.; Sainlos, M.; de Wit, J.; Choquet, D.; Thoumine, o.

10.1101/2021.03.16.435652 — neuroscience — Posted on 2021-03-17

2328 Signal complexity indicators of health status in clinical-EEG

Shen, K.; McFadden, A.; McIntosh, A. R.

10.1101/2021.03.16.435656 — neuroscience — Posted on 2021-03-17

2329 P-sort: an open-source software for cerebellar neurophysiology

Sedaghat-Nejad, E.; Fakharian, M. A.; Pi, J.; Hage, P.; Kojima, Y.; Soetedjo, R.; Ohmae, S.; Medina, J. F.; Shadmehr, R.

10.1101/2021.03.16.435644 — neuroscience — Posted on 2021-03-17

2330 Accurate reconstruction of dynamic gene expression and growth rate profiles from noisy measurements

Vidal Pena, G. A.; Vidal Cespedes, C. I.; rudge, t. j.

10.1101/2021.03.16.435606 — systems biology — Posted on 2021-03-17

2331 Integration of plant carbohydrate dynamics by Fourier polynomials

Seydel, C.; Biener, J.; Brodsky, V.; Eberlein, S.; Naegele, T.

10.1101/2021.03.16.435635 — plant biology — Posted on 2021-03-17

2332 FlywheelTools: Data Curation and Manipulation on the Flywheel Platform

Tapera, T. M.; Cieslak, M.; Bertolero, M.; Adebimpe, A.; Aguirre, G. K.; Butler, E. R.; Cook, P. A.; Davila, D.; Elliot, M. A.; Linguiti, S.; Murtha, K.; Tackett, W.; Detre, J. A.; Satterthwaite, T. D.

10.1101/2021.03.12.434998 — bioinformatics — Posted on 2021-03-17

2333 Cerebral biodistribution and real-time particle tracking in vivo of ultrabright fluorescent PLGA nano-carriers

Khalin, I.; Severi, C.; Heimburger, D.; Wehn, A.; Hellal, F.; Reisch, A.; Klymchenko, A.; Plesnila, N.

10.1101/2020.11.19.385062 — bioengineering — Posted on 2021-03-17

2334 Deconvolution of Expression for Nascent RNA Sequencing Data (DENR) Highlights Pre-RNA Isoform Diversity in Human Cells

Zhao, Y.; Dukler, N. E.; Barshad, G.; Toneyan, S.; Danko, C. G.; Siepel, A.

10.1101/2021.03.16.435537 — genomics — Posted on 2021-03-17

2335 Fitness costs and benefits of gene expression plasticity in rice under drought

Groen, S. C.; Hamann, E.; Calic, I.; Cochran, C.; Konshok, R.; Purugganan, M.; Franks, S. J.

10.1101/2021.03.16.435597 — evolutionary biology — Posted on 2021-03-17

2336 The assisting role of Polη in transcription facilitates formation of damage-induced cohesion

Ström, L.; Wu, P.-S.; Cameron, D. P.; Grosser, J.; Baranello, L.

10.1101/2020.12.20.423707 — cell biology — Posted on 2021-03-17

2337 Source imaging of high-density visual evoked potentials with multi-scale brain parcellations and connectomes

Pascucci, D.; Tourbier, S.; Rue-Queralt, J.; Carboni, M.; Hagmann, P.; Plomp, G.

10.1101/2021.03.16.435599 — neuroscience — Posted on 2021-03-17

2338 The developing brain structural and functional connectome fingerprint

Ciarrusta, J.; Christiaens, D.; Fitzgibbon, S. P.; Dimitrova, R.; Hutter, J.; Hughes, E.; Duff, E.; Price, A. N.; Cordero-Grande, L.; Tournier, J. D.; Rueckert, D.; Hajnal, J. V.; Arichi, T.; McAlonan, G.; Edwards, A. D.; Batalle, D.

10.1101/2021.03.08.434357 — neuroscience — Posted on 2021-03-17

2339 Loss of the glial glutamate transporter eaat2a leads to a combined developmental and epileptic encephalopathy in zebrafish

Hotz, A. L.; Jamali, A.; Rieser, N. N.; Niklaus, S.; Aydin, E.; Myren-Svelstad, S.; Lalla, L.; Jurisch-Yaksi, N.; Yaksi, E.; Neuhauss, S. C. F.

10.1101/2021.03.16.435577 — neuroscience — Posted on 2021-03-17

2340 Population differences in the length, early-life dynamics, and heritability of telomeres among European pied flycatchers

Karkkainen, T.; Laaksonen, T.; Burgess, M.; Cantarero, A.; Martinez-Padilla, J.; Potti, J.; Moreno, J.; Thomson, R. L.; Tilgar, V.; STIER, A.

10.1101/2021.03.16.435615 — zoology — Posted on 2021-03-17

2341 Structure of SOQ1 lumenal domains identifies potential disulfide exchange for negative regulation of photoprotection, qH

Yu, G.; Pan, X.; Hao, J.; Shi, L.; Zhang, Y.; Wang, J.; Xiao, Y.; Yang, F.; Lou, J.; Chang, W.; Malnoe, A.; Li, M.

10.1101/2021.03.16.435614 — plant biology — Posted on 2021-03-17

2342 Fast holographic scattering compensation for deep tissue biologicalimaging

May, M. A.; Barre, N.; Kummer, K.; Kress, M.; Ritsch-Marte, M.; Jesacher, A.

10.1101/2021.03.16.435380 — biophysics — Posted on 2021-03-17

2343 Combined fluorescence, optical diffraction tomography and Brillouin microscopy

Schlüssler, R.; Kim, K.; Nötzel, M.; Taubenberger, A. V.; Abuhattum, S.; Beck, T.; Müller, P.; Maharana, S.; Cojoc, G.; Girardo, S.; Hermann, A.; Alberti, S.; Guck, J.

10.1101/2020.10.30.361808 — biophysics — Posted on 2021-03-17

2344 Assessing the Role of Calmodulin's Linker Flexibility in Target Binding

Sun, B.; Kekenes-Huskey, P. M.

10.1101/2021.03.15.435522 — biophysics — Posted on 2021-03-17

2345 Natural Selection as the Sum Over All Histories.

Neal-Sturgess, C. E.

10.1101/2021.02.24.432748 — biophysics — Posted on 2021-03-17

2346 Buffering Updates Enables Efficient Dynamic de Bruijn Graphs

Alanko, J.; Alipanahi, B.; Settle, J.; Boucher, C.; Gagie, T.

10.1101/2021.03.16.435535 — bioinformatics — Posted on 2021-03-17

2347 Idefix: identifying accidental sample mix-ups in biobanks using polygenic scores

Warmerdam, R. C. A.; Lanting, P.; LifeLines Cohort Study, ; Deelen, P.; Franke, L.

10.1101/2021.03.12.435080 — bioinformatics — Posted on 2021-03-17

2348 Moving outside the lab: markerless motion capture accurately quantifies sagittal plane kinematics during the vertical jump

Drazan, J. F.; Phillips, W. T.; Seethapathi, N.; Hullfish, T. J.; Baxter, J. R.

10.1101/2021.03.16.435503 — bioengineering — Posted on 2021-03-17

2349 A Hierarchical 3D-motion Learning Framework for Animal Spontaneous Behavior Mapping

Huang, K.; Han, Y.; Chen, K.; Pan, H.; Yi, W.; Li, X.; Liu, S.; Wang, L.; Wei, P.

10.1101/2020.09.14.295808 — animal behavior and cognition — Posted on 2021-03-17

2350 Exploring Efficient Linear Mixed Models to Detect Quantitative Trait Locus-by-environment Interactions

Yamamoto, E.; Matsunaga, H.

10.1101/2020.07.25.220913 — genetics — Posted on 2021-03-17

2351 Sacsin cotranslational degradation causes autosomal recessive spastic ataxia of Charlevoix-Saguenay

Maltecca, F.; Longo, F.; De Ritis, D.; Miluzio, A.; Fraticelli, D.; Baets, J.; Scarlato, M.; Santorelli, F. M.; Biffo, S.

10.1101/2021.03.16.435646 — genetics — Posted on 2021-03-17

2352 Thermal biology of two sympatric Lacertids lizards (Lacerta diplochondrodes and Parvilacerta parva) from Western Anatolia

Kuyucu, A. C.; Sahin, M. K.

10.1101/2021.03.16.435405 — ecology — Posted on 2021-03-17

2353 The spatial network structure of intertidal meiofaunal communities derived from environmental DNA metabarcoding surveys in Northwest Iberia

Bellisario, B.; Fais, M.; Duarte, S.; Vieira, P.; Canchaya, C.; Costa, F.

10.1101/2021.03.16.435605 — ecology — Posted on 2021-03-17

2354 Artificial Intelligence Approaches to Assessing Primary Cilia

Bansal, R.; Engle, S. E.; Kamba, T. K.; Brewer, K.; Lewis, W. R.; Berbari, N. F.

10.1101/2021.02.03.429602 — cell biology — Posted on 2021-03-17

2355 Finger representation in the cortex of the congenitally blind

Wesselink, D. B.; Kikkert, S.; Bridge, H.; Makin, T. R.

10.1101/2021.03.16.435392 — neuroscience — Posted on 2021-03-17

2356 Effects of order on memory of event times

Naim, M.; Katkov, M.; Tsodyks, M.

10.1101/2020.09.11.289058 — neuroscience — Posted on 2021-03-17

2357 A hierarchy of linguistic predictions during natural language comprehension

Heilbron, M.; Armeni, K.; Schoffelen, J.-M.; Hagoort, P.; de Lange, F. P.

10.1101/2020.12.03.410399 — neuroscience — Posted on 2021-03-17

2358 Florigen governs shoot regeneration.

Kutsher, Y.; Fisler, M.; Faigenboim, A.; Reuveni, M.

10.1101/2021.03.16.435564 — plant biology — Posted on 2021-03-17

2359 Response of rhizobial strains on biochemical traits and nutrient uptake in Mungbean (Vigna radiata L. Wilczek) under moisture stress

Yadav, S.; Sharma, K. D.

10.1101/2021.03.16.435312 — physiology — Posted on 2021-03-17

2360 Enhancing the localization precision of single molecule localization microscopy by analyzing Brownian motion of individual fluorescent probe

Ni, J.; Cao, B.; Niu, G.; Xu, C.; Ni, Y.

10.1101/2021.03.16.435087 — biophysics — Posted on 2021-03-17

2361 High rates of genome rearrangements and pathogenicity of Shigella spp.

Seferbekova, Z.; Zabelkin, A.; Yakovleva, Y.; Afasizhev, R.; Dranenko, N.; Alexeev, N.; Gelfand, M. S.; Bochkareva, O. O.

10.1101/2020.06.12.147751 — bioinformatics — Posted on 2021-03-17

2362 Integrated single-cell transcriptomics and epigenomics reveals strong germinal center-associated etiology of autoimmune risk loci

King, H. W.; Wells, K. L.; Shipony, Z.; Kathiria, A. S.; Wagar, L. E.; Lareau, C.; Orban, N.; Capasso, R.; Davis, M. M.; Steinmetz, L. M.; James, L. K.; Greenleaf, W. J.

10.1101/2021.03.16.435578 — genomics — Posted on 2021-03-17

2363 Cost efficiency of institutional incentives in finite populations

Duong, M. H.; Han, T. A.

10.1101/2021.03.16.435569 — evolutionary biology — Posted on 2021-03-17

2364 Dietary habits of free-ranging banded langur (Presbytis femoralis) in a secondary-human modified forest in Johor, Malaysia

Najmuddin, M. F.; Haris, H.; Norazlimi, N.; Ruslin, F.; Matsuda, I.; Md-Zain, B. M.; Abdul-Latiff, M. A. B.

10.1101/2021.03.16.435588 — ecology — Posted on 2021-03-17

2365 CRYPTOCHROME suppresses the circadian proteome and promotes protein homeostasis

Wong, D. C. S.; Seinkmane, E.; Stangherlin, A.; Zeng, A.; Rzechorzek, N. M.; Beale, A. D.; Day, J.; Reed, M.; Peak-Chew, S. Y.; Styles, C. T.; Edgar, R. S.; Putker, M.; O'Neill, J. S.

10.1101/2020.05.16.099556 — cell biology — Posted on 2021-03-17

2366 Time dependent proinflammatory responses shape virus interference during coinfections of influenza A virus and influenza D virus

Guan, M.; Blackmon, S.; Olivier, A. K.; Zhang, X.; Liu, L.; Woolums, A.; Crenshaw, M. A.; Liao, S.; Webby, R. J.; Epperson, W. B.; Wan, X.-F.

10.1101/2021.03.14.435363 — microbiology — Posted on 2021-03-17

2367 Functional development of a V3-specific broadly neutralizing antibody isolated from a case of HIV superinfection

Shipley, M. M.; Mangala Prasad, V.; Doepker, L. E.; Dingens, A. S.; Ralph, D. K.; Harkins, E.; Dhar, A.; Arenz, D.; Chohan, V.; Weight, H.; Mandaliya, K.; Bloom, J. D.; Matsen, F.; Lee, K. K.; Overbaugh, J. M.

10.1101/2021.03.15.435484 — microbiology — Posted on 2021-03-17

2368 Chronic neuronal excitation leads to homeostatic suppression of structural long-term potentiation

Ueda, H. H.; Sato, A.; Onda, M.; Murakoshi, H.

10.1101/2021.03.16.435575 — neuroscience — Posted on 2021-03-17

2369 Large scale measurement of protein synthesis rates over the diurnal cycle reveal pathway specific regulation of translation

Duncan, O.; Millar, A. H.

10.1101/2021.03.15.435498 — plant biology — Posted on 2021-03-17

2370 Intra and inter-annual climatic conditions have stronger effect than grazing intensity on root growth of permanent grasslands

Picon-Cochard, C.; Vassal, N.; Martin, R.; Herfurth, D.; Note, P.; Louault, F.

10.1101/2020.08.23.263137 — ecology — Posted on 2021-03-17

2371 Differential detection of Tomato mosaic virus (ToMV) and Tomato brown rugose fruit virus (ToBRFV) using CRISPR-Cas12

Alon, D.; Hak, H.; Bornstein, M.; Pines, G.; Spiegelman, Z.

10.1101/2021.03.16.435580 — molecular biology — Posted on 2021-03-17

2372 Rat ultrasonic vocalizations and novelty-induced social and non-social investigation behavior in a seminatural environment

Heinla, I.; Chu, X.; Agmo, A.; Snoeren, E.

10.1101/2021.03.16.435680 — neuroscience — Posted on 2021-03-17

2373 EFFICACY OF DISTRIBUTED TRAINING DEPENDS ON THE DORSO-LATERAL STRIATUM

Mastrorilli, V.; Centofante, E.; Antonelli, F.; Rinaldi, A.; Mele, A.

10.1101/2021.03.17.435609 — neuroscience — Posted on 2021-03-17

2374 fmr1 mutation interacts with sensory experience to alter the early development of behavior and sensory coding in zebrafish

Zhu, S.; McCullough, M.; Pujic, Z.; Sibberas, J.; Sun, B.; Bucknall, B.; Avitan, L.; Goodhill, G.

10.1101/2021.03.16.435742 — neuroscience — Posted on 2021-03-17

2375 Low pathogenic avian influenza virus infection retards colon microbiome diversification in two different chicken lines

Chrzastek, K.; Leng, J.; Zakaria, M. K.; Bialy, D.; La Ragione, R.; Shelton, H.

10.1101/2021.03.15.435422 — microbiology — Posted on 2021-03-17

2376 Conflict detection in a sequential decision task is associated with increased cortico-subthalamic coherence and prolonged subthalamic oscillatory response in the beta band.

Patai, E. Z.; Foltynie, T.; Limousin, P.; Zrinzo, L.; Bogacz, R.; Litvak, V.

10.1101/2020.06.09.141713 — neuroscience — Posted on 2021-03-17

2377 Toward quantifying the adaptive role of bacterial pangenomes during environmental perturbations

Conrad, R. E.; Viver, T.; Gago, J. F.; Hatt, J. K.; Venter, F.; Rossello-Mora, R.; Konstantinidis, K. T.

10.1101/2021.03.15.435471 — microbiology — Posted on 2021-03-17

2378 Diverse mobile genetic elements support the persistence of listeria monocytogenes on dairy farms

Castro, H.; Douillard, F.; Korkeala, H.; Lindström, M.

10.1101/2021.03.15.435412 — microbiology — Posted on 2021-03-17

2379 Rap-Phr systems in B. subtilis 3610 affect matrix gene expression and play a role in biofilm formation in vitro and on the plant root

Christensen, M. N.; Rosenbek Mortensen, R. M.; Kirk, N. K.; Gallegos-Monterrosa, R.; Kovacs, A. T.

10.1101/2021.03.15.435437 — microbiology — Posted on 2021-03-17

2380 Prolonged development of long-term potentiation at lateral entorhinal cortex synapses onto adult-born neurons

Vyleta, N. P.; Snyder, J. S.

10.1101/2021.03.15.435460 — neuroscience — Posted on 2021-03-17

2381 BCL-XL blockage in TNBC models confers vulnerability to inhibition of specific cell cycle regulators

Castellanet, O.; Ahmad, F.; Vinik, Y.; Mills, G. B.; Habermann, B. H.; Borg, J.-P. H.; Lev, S.; Lamballe, F.; Maina, F.

10.1101/2021.03.16.435600 — cancer biology — Posted on 2021-03-17

2382 Targeting Glioblastoma Signaling and Metabolism with A Re-Purposed Brain-Penetrant Drug

Bi, J.; Khan, A.; Tang, J.; Wu, S.; Zhang, W.; Gimple, R. C.; Koga, T.; Armando, A. M.; Miki, S.; Yang, H.; Prager, B.; Curtis, E. J.; Wainwright, D. A.; Furnari, F. B.; Rich, J. N.; Cloughesy, T. F.; Quehenberger, O.; Kornblum, H. I.; Rzhetsky, A.; Cravatt, B. F.; Mischel, P. S.

10.1101/2021.03.16.435487 — cancer biology — Posted on 2021-03-17

2383 overlappingCGM: Automatic detection and analysis of overlapping co-expressed gene modules

Nguyen, Q.-H.; Le, D.-H.

10.1101/2021.03.15.435373 — bioinformatics — Posted on 2021-03-17

2384 The long-term effects of genomic selection: Response to selection, additive genetic variance and genetic architecture

Wientjes, Y. C. J.; Bijma, P.; Calus, M. P. L.; Zwaan, B. J.; Vitezica, Z. G.; van den Heuvel, J.

10.1101/2021.03.16.435664 — genetics — Posted on 2021-03-16

2385 Plant responses to multiple antagonists are mediated by order of attack and phytohormone crosstalk

Basu, S.; Clark, R. E.; Bera, S.; Casteel, C. L.; Crowder, D. W.

10.1101/2021.02.17.431727 — ecology — Posted on 2021-03-17

2386 Ecdysone coordinates plastic growth with robust pattern in the developing wing

Nogueira Alves, A.; Oliveira, M. M.; Koyama, T.; Shingleton, A.; Mirth, C.

10.1101/2020.12.16.423141 — developmental biology — Posted on 2021-03-17

2387 A high throughput SEC23 functional interaction screen reveals a role for focal adhesion and extracellular matrix signalling in the regulation of COPII subunit SEC23A

Jung, J.; Khan, M. M.; Landry, J.; Halavatyi, A.; Machado, P.; Reiss, M.; Pepperkok, R.

10.1101/2021.03.16.435679 — cell biology — Posted on 2021-03-17

2388 Single Prolonged Stress Reduces Intrinsic Excitability and Excitatory Synaptic Drive onto Pyramidal Neurons in the Infralimbic Prefrontal Cortex of Adult Rats

Nawreen, N.; Baccei, M. L.; Herman, J.

10.1101/2021.03.16.435686 — neuroscience — Posted on 2021-03-16

2389 Decoding the Information Structure Underlying the Neural Representation of Concepts

Fernandino, L.; Conant, L. L.; Humphries, C. J.; Binder, J. R.

10.1101/2021.03.16.435524 — neuroscience — Posted on 2021-03-16

2390 Myelin contributes to microstructural growth in human sensory cortex during early infancy.

Rosenke, M.; Natu, V. S.; Wu, H.; Querdasi, F. R.; Kular, H.; Lopez-Alvarez, N.; Grotheer, M.; Berman, S.; Mezer, A.; Grill-Spector, K.

10.1101/2021.03.16.435703 — neuroscience — Posted on 2021-03-16

2391 Using machine learning and big data to explore the drug resistance landscape in HIV

BLASSEL, L.; TOSTEVIN, A.; VILLABONA-ARENAS, C. J.; PEETERS, M.; HUE, S.; GASCUEL, O.

10.1101/2021.03.16.435621 — bioinformatics — Posted on 2021-03-16

2392 The salmon louse genome: copepod features and parasitic adaptations.

Skern-Mauritzen, R.; Malde, K.; Eichner, C.; Dondrup, M.; Furmanek, T.; Besnier, F.; Komisarczuk, A. Z.; Nuhn, M.; Dalvin, S.; Edvardsen, R. B.; Grotmol, S.; Karlsbakk, E.; Kersey, P.; Leong, J. S.; Glover, K. A.; Lien, S.; Jonassen, I.; Koop, B. F.; Nilsen, F.

10.1101/2021.03.15.435234 — genomics — Posted on 2021-03-16

2393 Bloom syndrome helicase contributes to germ line development and longevity in zebrafish

Annus, T.; Müller, D.; Jezso, B.; Ullaga, G.; Harami, G. M.; Orban, L.; Kovacs, M.; Varga, M.

10.1101/2021.03.16.435627 — genetics — Posted on 2021-03-16

2394 DNA Methylation Networks Underlying Mammalian Traits

Haghani, A.; Lu, A. T.; Li, C. Z.; Robeck, T. R.; Belov, K.; Breeze, C. E.; Brooke, R. T.; Clarke, S.; Faulkes, C. G.; Fei, Z.; Ferguson, S. H.; Finno, C. J.; Gladyshev, V. N.; Gorbunova, V.; Goya, R. G.; Hogan, A. N.; Hogg, C. J.; Hore, T. A.; Kiaris, H.; Kordowitzki, P.; Banks, G.; Koski, W. R.; Mozhui, K.; Naderi, A.; Ostrander, E. A.; Parsons, K. M.; Plassais, J.; Robbins, J.; Sears, K. E.; Seluanov, A.; Steinman, K. J.; Szladovits, B.; Thompson, M. J.; Villar, D.; Wang, N.; Wilkinson, G. S.; Young, B. G.; Zhang, J.; Zoller, J. A.; Ernst, J.; Yang, X. W.; Raj, K.; Horvath, S.

10.1101/2021.03.16.435708 — evolutionary biology — Posted on 2021-03-16

2395 Climate Change Controls Phosphorus Transport from the Watershed into Lake Kinneret (Israel)

Gophen, M.

10.1101/2021.03.16.435628 — ecology — Posted on 2021-03-16

2396 Vegfr3-tdTomato, a reporter mouse for microscopic visualization of lymphatic vessel by multiple modalities

Kirschnick, N.; Redder, E.; Hägerling, R.; Hansmeier, N. R.; Kiefer, F.

10.1101/2021.03.16.435629 — cell biology — Posted on 2021-03-16

2397 High-affinity P2Y2 and low-affinity P2X7 receptor interaction modulates ATP-mediated calcium signaling in murine osteoblasts

Khadra, A.; Mikolajewicz, N.; Smith, D.; Komarova, S. V.

10.1101/2021.03.16.435624 — cell biology — Posted on 2021-03-16

2398 Micrometer-resolution reconstruction and analysis of whole mouse brain vasculature by synchrotron-based phase-contrast tomographic microscopy

Miettinen, A.; Zippo, A.; Patera, A.; Bonnin, A.; Shahmoradian, S.; Biella, G.; Stampanoni, M.

10.1101/2021.03.16.435616 — neuroscience — Posted on 2021-03-16

2399 The neural mechanisms of active removal from working memory

Shan, J.; Postle, B.

10.1101/2021.03.16.435617 — neuroscience — Posted on 2021-03-16

2400 Causal-inference regulates audiovisual spatial recalibration via its influence on audiovisual perception

Hong, F.; Badde, S.; Landy, M.

10.1101/2021.03.16.435619 — neuroscience — Posted on 2021-03-16

2401 Multicellular Spatial Model of RNA Virus Replication and Interferon Responses Reveals Factors Controlling Plaque Growth Dynamics

Aponte-Serrano, J. O.; Weaver, J. J. A.; Sego, T. J.; Glazier, J. A.; Shoemaker, J. E.

10.1101/2021.03.16.435618 — systems biology — Posted on 2021-03-16

2402 No-U-Turn sampling for phylogenetic trees

Wahle, J.

10.1101/2021.03.16.435623 — bioinformatics — Posted on 2021-03-16

2403 A graph-based cell tracking algorithm with few manually tunable parameters and automated segmentation error correction

Löffler, K.; Scherr, T.; Mikut, R.

10.1101/2021.03.16.435631 — bioinformatics — Posted on 2021-03-16

2404 Single-cell transcriptome profiling simulation reveals the impact of sequencing parameters and algorithms on clustering

Liu, Y.; Shi, B.; Wu, A.; Peng, X.; Yuan, Z.; Liu, G.; Liu, L.

10.1101/2021.03.16.435626 — bioinformatics — Posted on 2021-03-16

2405 Birdsong Phrase Verification and Classification Using Siamese Neural Networks

Renteria, S.; Vallejo, E.; Taylor, C.

10.1101/2021.03.16.435625 — bioinformatics — Posted on 2021-03-16

2406 Low adenovirus vaccine doses administered to skin using microneedle patches induce better functional antibody immunogenicity as compared to systemic injection.

Flynn, O.; Dillane, K.; Sousa Lanza, J.; Marshall, J. M.; Jin, J.; Silk, S. E.; Draper, S. J.; Moore, A. C.

10.1101/2021.01.21.427553 — immunology — Posted on 2021-03-16

2407 Unraveling micro-architectural modulations in neural tissue upon ischemia by Correlation Tensor MRI

Alves, R.; Henriques, R. N.; Kerkela, L.; Chavarrias, C.; Jespersen, S.; Shemesh, N.

10.1101/2021.02.20.432088 — neuroscience — Posted on 2021-03-16

2408 The role of vimentin-nuclear interactions in persistent cell motility through confined spaces

Gupta, S.; Patteson, A. E.; Schwarz, J.

10.1101/2021.03.16.435670 — biophysics — Posted on 2021-03-16

2409 Structure of an infectious mammalian prion

Kraus, A.; Hoyt, F.; Schwartz, C.; Hansen, B.; Hughson, A. G.; Artikis, E.; Race, B.; Caughey, B.

10.1101/2021.02.14.431014 — biochemistry — Posted on 2021-03-16

2410 Parasitic wasps do not lack lipogenesis

Ruther, J.; Prager, L.; Pokorny, T.

10.1101/2021.03.16.435583 — biochemistry — Posted on 2021-03-16

2411 Community Evaluation of Glycoproteomics Informatics Solutions Reveals High-Performance Search Strategies of Glycopeptide Data

Kawahara, R.; Alagesan, K.; Bern, M.; Cao, W.; Chalkley, R. J.; Cheng, K.; Choo, M. S.; Edwards, N.; Goldman, R.; Hoffmann, M.; Hu, Y.; Huang, Y.; Kim, J. Y.; Kletter, D.; Liquet-Weiland, B.; Liu, M.; Mechref, Y.; Meng, B.; Neelamegham, S.; Nguyen-Khuong, T.; Nilsson, J.; Pap, A.; Park, G. W.; Parker, B. L.; Pegg, C. L.; Penninger, J. M.; Phung, T. K.; Pioch, M.; Rapp, E.; Sakalli, E.; Sanda, M.; Schulz, B. L.; Scott, N. E.; Sofronov, G.; Stadlmann, J.; Vakhrushev, S. Y.; Woo, C. M.; Wu, H.-Y.; Yang, P.; Ying, W.; Zhang, H.; Zhang, Y.; Zhao, J.; Zaia, J.; Haslam, S. M.; Palmisano, G.; Yoo, J.

10.1101/2021.03.14.435332 — biochemistry — Posted on 2021-03-16

2412 Target enrichment and extensive population sampling help untangle the recent, rapid radiation of Oenothera sect. Calylophus

Cooper, B. J.; Moore, M. J.; Douglas, N. A.; Wagner, W. L.; Johnson, M. G.; Overson, R. P.; McDonnell, A. J.; Levin, R. A.; Raguso, R. A.; Flores Olvera, H.; Ochoterena, H.; Fant, J. B.; Skogen, K. A.; Wickett, N. J.

10.1101/2021.02.20.432097 — evolutionary biology — Posted on 2021-03-16

2413 The disproportionate effect of drift on a hypervariable master regulator of density

Benard, A.; Henri, H.; Nous, C.; Vavre, F.; Kremer, N.

10.1101/2020.11.29.402545 — evolutionary biology — Posted on 2021-03-16

2414 Comparing diversification rates in lakes, rivers, and the sea

Miller, E. C.

10.1101/2020.05.24.113761 — evolutionary biology — Posted on 2021-03-16

2415 In vivo lentiviral vector gene therapy to cure hereditary tyrosinemia type 1 and prevent development of precancerous and cancerous lesions

Nicolas, C.; Van Lith, C.; Allen, K.; Hickey, R.; Du, Z.; Hillin, L.; Guthman, R.; Cao, W.; Bhagwate, A.; O'Brien, D.; Kocher, J.-P.; Kaiser, R. A.; Russell, S.; Lillegard, J.

10.1101/2021.01.02.425079 — cell biology — Posted on 2021-03-16

2416 HIV-1 Vpr Induces Degradation of Nucleolar Protein CCDC137 as a Consequence of Cell Cycle Arrest

Martins, L. J.; DePaula-Silva, A. B.; Planelles, V.

10.1101/2021.03.16.435666 — microbiology — Posted on 2021-03-16

2417 AC2P20 selectively kills M. tuberculosis at acidic pH by depleting free thiols

Dechow, S. J.; Coulson, G. B.; Wilson, M. W.; Larsen, S. D.; Abramovitch, R. B.

10.1101/2021.03.16.435645 — microbiology — Posted on 2021-03-16

2418 Rationally designed immunogens enable immune focusing to the SARS-CoV-2 receptor binding motif

Hauser, B. M.; Sangesland, M.; St. Denis, K.; Feldman, J.; Lam, E. C.; Kannegieter, T.; Balazs, A. B.; Lingwood, D.; Schmidt, A. G.

10.1101/2021.03.15.435440 — immunology — Posted on 2021-03-16

2419 CISH targeting in NK cells activates natural cytotoxicity receptor signaling and reduce cell exhaustion to unsilence primary anti-tumor response

Bernard, P.-L.; Delconte, R.; Pastor, S.; Laletin, V.; Goubard, A.; Josselin, E.; Castellano, R.; Vernerey, J.; Vivier, E.; Huntington, N.; Nunes, J.; Guittard, G.

10.1101/2021.03.16.435571 — immunology — Posted on 2021-03-16

2420 An egg-derived sulfated N-Acetyllactosamine glycan is an antigenic decoy of influenza virus vaccines

Guthmiller, J. J.; Utset, H. A.; Henry, C.; Li, L.; Zheng, N.-Y.; Sun, W.; Vieira, M. C.; Zost, S.; Huang, M.; Hensley, S. E.; Cobey, S.; Palese, P.; Wilson, P. C.

10.1101/2021.03.16.435673 — immunology — Posted on 2021-03-16

2421 MicroMator: Open and Flexible Software for Reactive Microscopy

Fox, Z. R.; Fletcher, S.; Fraisse, A.; Aditya, C.; Sosa-Carrillo, S.; Gilles, S.; Bertaux, F.; Ruess, J.; Batt, G.

10.1101/2021.03.12.435206 — systems biology — Posted on 2021-03-16

2422 SiGMoiD: A super-statistical generative model for binary data

Zhao, X.; Plata, G.; Dixit, P. D.

10.1101/2020.10.14.338277 — systems biology — Posted on 2021-03-16

2423 CancerVar: an Artificial Intelligence empowered platform for clinical interpretation of somatic mutations in cancer

Li, Q.; Ren, Z.; Zhou, Y.; Wang, K.

10.1101/2020.10.06.323162 — cancer biology — Posted on 2021-03-16

2424 Noncanonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α promotes cancer-cell survival

Le Thomas, A.; Ferri, E.; Marsters, S.; Harnoss, J. M.; Modrusan, Z.; Li, W.; Rudolph, J.; Wang, W.; Wu, T. D.; Walter, P.; Ashkenazi, A.

10.1101/2021.03.16.435520 — cancer biology — Posted on 2021-03-16

2425 Towards the NMR solution Structure and the Dynamics of the C-terminal Region of APOL1 and its G1, G2 Variants with a Membrane Mimetic

Madhavan, S. M.; Hansen, A. L.; Cao, S.; Sedor, J. R.; Buck, M.

10.1101/2021.03.16.435683 — biophysics — Posted on 2021-03-16

2426 A Comprehensive Analysis of Allostery in 14-3-3 ζ Docking Proteins using the Spatial Convolution Model (SCM)

Davis, L. K.

10.1101/2021.03.15.243386 — biophysics — Posted on 2021-03-16

2427 A physical theory of movement in small animals

Loveless, J.; Garner, A.; Issa, A. R.; Roberts, R. J. V.; Webb, B.; Prieto-Godino, L. L.; Ohyama, T.; Alonso, C.

10.1101/2020.08.25.266163 — biophysics — Posted on 2021-03-16

2428 GTP and lipids control self-assembly and functional promiscuity of Dynamin2 molecular machinery

Espadas, J.; Bocanegra, R.; Martinez Galvez, J. M.; Largo, E.; Banos-Mateos, S.; Arrasate, P.; Ormaetxea Guisasola, J.; Velasco del Olmo, A.; Vera Lillo, J.; Ibarra, B.; Shnyrova, A. V.; Frolov, V. A.

10.1101/2021.03.15.435402 — biophysics — Posted on 2021-03-16

2429 Efficient and precise single-cell reference atlas mapping with Symphony

Kang, J. B.; Nathan, A.; Zhang, F.; Millard, N.; Rumker, L.; Moody, D. B.; Korsunsky, I.; Raychaudhuri, S.

10.1101/2020.11.18.389189 — bioinformatics — Posted on 2021-03-16

2430 A novel heteromeric pantothenate kinase complex in apicomplexan parasites

Tjhin, E. T.; Howieson, V. M.; Spry, C.; van Dooren, G. G.; Saliba, K. J.

10.1101/2021.03.16.435557 — biochemistry — Posted on 2021-03-16

2431 Metagenomic analysis reveals the signature of gut microbiota associated with human chronotypes

Carasso, S.; Fishman, B.; Stelmach Lask, L.; Shochat, T.; Geva-Zatorsky, N.; Tauber, E.

10.1101/2021.03.16.435653 — genomics — Posted on 2021-03-16

2432 Pathogen-driven coevolution across CBP60 plant immune regulator subfamilies confers resilience on the regulator module

Zheng, Q.; Majsec, K.; Katagiri, F.

10.1101/2020.07.16.207134 — evolutionary biology — Posted on 2021-03-16

2433 The arrested state of processing bodies supports mRNA regulation in early development

Sankaranarayanan, M.; Emenecker, R. J.; Jahnel, M.; Trussina, I. R. E. A.; Wayland, M. T.; Alberti, S.; Holehouse, A. S.; Weil, T. T.

10.1101/2021.03.16.435709 — cell biology — Posted on 2021-03-16

2434 SMC Complexes Are Guarded by the SUMO Protease Ulp2 Against SUMO-Chain-Mediated Turnover

Psakhye, I.; Branzei, D.

10.1101/2020.11.13.381483 — cell biology — Posted on 2021-03-16

2435 Establishment of Developmental Gene Silencing by Ordered Polycomb Complex Recruitment in Early Zebrafish Embryos

Cairns, B. R.; Hickey, G. J. M.; Wike, C.; Nie, X.; Guo, Y.; Murphy, P. J.; Tan, M.

10.1101/2021.03.16.435592 — molecular biology — Posted on 2021-03-16

2436 Replication kinetic, cell tropism and associated immune responses in SARS-CoV-2 and H5N1 virus infected human iPSC derived neural models

Bauer, L.; Lendemeijer, B.; Leijten, L.; Embregts, C. W. E.; Rockx, B.; Kushner, S. A.; de Vrij, F. M. S.; van Riel, D.

10.1101/2021.03.15.435472 — microbiology — Posted on 2021-03-16

2437 Killed whole genome-reduced bacteria surface-expressed coronavirus fusion peptide vaccines protect against disease in a porcine model

Maeda, D. L. N. F.; Tian, D.; Yu, H.; Dar, N.; Rajasekaran, V.; Meng, S.; Mahsoub, H.; Sooryanarain, H.; Wang, B.; Heffron, C. L.; Hassebroek, A.; LeRoith, T.; Meng, X.-J.; Zeichner, S. L.

10.1101/2021.03.15.435497 — microbiology — Posted on 2021-03-16

2438 Inflammatory signals are sufficient to elicit TOX expression in mouse and human CD8 T cells

Maurice, N. J.; Berner, J.; Taber, A. K.; Zehn, D.; Prlic, M.

10.1101/2021.03.15.435527 — immunology — Posted on 2021-03-16

2439 Circular RNA Vaccines against SARS-CoV-2 and Emerging Variants

Qu, L.; Yi, Z.; Shen, Y.; Xu, Y.; Wu, Z.; Tang, H.; Xiao, X.; Dong, X.; Guo, L.; Yisimayi, A.; Cao, Y.; Zhou, Z.; Wang, J.; Xie, X. S.; Wei, W.

10.1101/2021.03.16.435594 — immunology — Posted on 2021-03-16

2440 REAP: A platform to identify autoantibodies that target the human exoproteome

10.1101/2021.02.11.430703 — immunology — Posted on 2021-03-16

2441 Electrophysiological correlates of mood and reward dynamics in human adolescents

Liuzzi, L.; Chang, K. K.; Keren, H.; Saha, D.; Zheng, C.; Nielson, D. M.; Stringaris, A.

10.1101/2021.03.04.433969 — neuroscience — Posted on 2021-03-16

2442 Schizophrenia-linked protein tSNARE1 regulates endolysosomal trafficking in cortical neurons

Plooster, M.; Farrell, M. S.; Rossi, G.; Won, H.; Gupton, S. L.; Brennwald, P. J.

10.1101/2021.02.09.430442 — neuroscience — Posted on 2021-03-16

2443 Programming Cell-Free Biosensors with DNA Strand Displacement Circuits

Jung, J. K.; Alam, K. K.; Lucks, J. B.

10.1101/2021.03.16.435693 — synthetic biology — Posted on 2021-03-16

2444 The phosphoproteome of rice leaves responds to water and nitrogen supply

Hamzelou, S.; Melino, V. J.; Plett, D. C.; Kamath, K. S.; Nawrocki, A.; Larsen, M. R.; Atwell, B. J.; Haynes, P. A.

10.1101/2021.03.15.435047 — plant biology — Posted on 2021-03-16

2445 Discovery of SARS-CoV-2 papain-like protease inhibitors through a combination of high-throughput screening and FlipGFP-based reporter assay

Xia, Z.; Sacco, M.; Ma, C.; Townsend, J.; Kitamura, N.; Hu, Y.; Ba, M.; Szeto, T.; Zhang, X.; Meng, X.; Zhang, F.; Xiang, Y.; Marty, M.; Chen, Y.; Wang, J.

10.1101/2021.03.15.435551 — pharmacology and toxicology — Posted on 2021-03-16

2446 Role of bacterial persistence in spatial population expansion

Patra, P.; Klumpp, S.

10.1101/2021.03.16.435668 — biophysics — Posted on 2021-03-16

2447 phastSim: efficient simulation of sequence evolution for pandemic-scale datasets

De Maio, N.; Weilguny, L.; Walker, C. R.; Turakhia, Y.; Corbett-Detig, R.; Goldman, N.

10.1101/2021.03.15.435416 — bioinformatics — Posted on 2021-03-16

2448 Immunoinformatic Approach for the identification of T Cell and B Cell Epitopes in the Surface Glycoprotein and Designing a Potent Multiepitope Vaccine Construct Against SARS-CoV-2 including the new UK variant

Krishnasamy, K.; Selvaraj, G. F.; Ramesh, K.; Padmanabhan, P.; Gopalan, V.; Govindan, K.; Chandran, A.; Sivasubramanian, S.

10.1101/2021.03.15.435391 — bioinformatics — Posted on 2021-03-16

2449 Powering electronic implants by high frequency volume conduction: in human validation

Minguillon, J.; Tudela-Pi, M.; Becerra-Fajardo, L.; Perera, E.; del-Ama, A. J.; Gil-Agudo, A.; Megia-Garcia, A.; Garcia-Moreno, A.; Ivorra, A.

10.1101/2021.03.15.435404 — bioengineering — Posted on 2021-03-16

2450 3D genomic capture of regulatory immuno-genetic profiles in COVID-19 patients for prognosis of severe COVID disease outcome

Hunter, E.; Koutsothanasi, C.; Wilson, A.; Santos, F. C.; Salter, M.; Powell, R.; Dring, A.; Brajer, P.; Egan, B.; Westra, J.; Ramadass, A.; Messner, W.; Brunton, A.; Lyski, Z.; Vancheeswaran, R.; Barlow, A.; Pchejetski, D.; Robbins, P.; Mellor, J.; Akoulitchev, A.

10.1101/2021.03.14.435295 — biochemistry — Posted on 2021-03-16

2451 Electrochemical measurements reveal reactive oxygen species in stress granules.

Hu, K.; Relton, E.; Locker, N.; Phan, N. T.; Ewing, A. G.

10.1101/2021.03.16.435640 — biochemistry — Posted on 2021-03-16

2452 Sulfonated rhodamines as impermeable labelling substrates for cell surface protein visualization

Birke, R.; Ast, J.; Roosen, D. A.; Mathes, B.; Rossmann, K.; Huhn, C.; Jones, B.; Lehmann, M.; Haucke, V.; Hodson, D.; Broichhagen, J.

10.1101/2021.03.16.435698 — biochemistry — Posted on 2021-03-16

2453 Proteome remodeling in the Mycobacterium tuberculosis PknG knockout: molecular evidence for the role of this kinase in cell envelope biogenesis and hypoxia response.

Lima, A.; Leyva, A.; Rivera, B.; Portela, M. M.; Gil, M.; Cascioferro, A.; Lisa, M. N.; Wehenkel, A. M.; Bellinzoni, M.; Carvalho, P.; Batthyany, C.; Alvarez, M. N.; Brosch, R.; Alzari, P. M.; Duran, R.

10.1101/2021.03.16.435434 — biochemistry — Posted on 2021-03-16

2454 Identity and compatibility of reference genome resources

Stolarczyk, M.; Xue, B.; Sheffield, N. C.

10.1101/2021.03.15.435425 — genomics — Posted on 2021-03-16

2455 Genetically Encoded CRISPR components Yield Efficient Gene Editing in the Invasive Pest, Drosophila suzukii

Kandul, N. P.; Belikoff, E. J.; Liu, J.; Buchman, A.; Li, F.; Yamamoto, A.; Yang, T.; Shriner, I.; Scott, M. J.; Akbari, O.

10.1101/2021.03.15.435483 — genetics — Posted on 2021-03-16

2456 Eukaryotic initiation factor EIF-3.G augments mRNA translation efficiency to regulate neuronal activity.

Blazie, S. M.; Takayanagi-Kiya, S.; McCulloch, K. M.; Jin, Y.

10.1101/2021.03.15.435499 — genetics — Posted on 2021-03-16

2457 The Most Parsimonious Reconciliation Problem in the Presence of Incomplete Lineage Sorting and Hybridization is NP-Hard

LeMay, M.; Wu, Y.-C.; Libeskind-Hadas, R.

10.1101/2021.03.14.435321 — evolutionary biology — Posted on 2021-03-16

2458 Complementary resource preferences spontaneously emerge in diauxic microbial communities

Wang, Z.; Goyal, A.; Dubinkina, V.; George, A. B.; Wang, T.; Fridman, Y.; Maslov, S.

10.1101/2021.03.16.435669 — ecology — Posted on 2021-03-16

2459 Single cell RNA sequencing of the Strongylocentrotus purpuratus larva reveals the blueprint of major cell types and nervous system of a non-chordate deuterostome

Paganos, P.; Voronov, D.; Musser, J.; Arendt, D.; Arnone, M. I.

10.1101/2021.03.16.435574 — developmental biology — Posted on 2021-03-16

2460 DNA spike-ins enable confident interpretation of SARS-CoV-2 genomic data from amplicon-based sequencing

Lagerborg, K. A.; Normandin, E.; Bauer, M. R.; Adams, G.; Figueroa, K.; Loreth, C.; Gladden-Young, A.; Shaw, B.; Pearlman, L.; Shenoy, E. S.; Hooper, D.; Pierce, V. M.; Zachary, K. C.; Park, D. J.; MacInnis, B. L.; Lemieux, J. E.; Sabeti, P. C.; Reilly, S. K.; Siddle, K. J.

10.1101/2021.03.16.435654 — molecular biology — Posted on 2021-03-16

2461 Pyrolyzed substrates induce aromatic compound metabolism in the post-fire fungus, Pyronema domesticum

Fischer, M. S.; Stark, F. G.; Berry, T. D.; Zeba, N.; Whitman, T.; Traxler, M. F.

10.1101/2021.03.15.435558 — microbiology — Posted on 2021-03-16

2462 Overexpression of the RNA-binding protein NrdA affects global gene expression and secondary metabolism in Aspergillus species

Kadooka, C.; Izumitsu, K.; Asai, T.; Mori, K.; Okutsu, K.; Yoshizaki, Y.; Takamine, K.; Goto, M.; Tamaki, H.; Futagami, T.

10.1101/2021.03.15.435561 — microbiology — Posted on 2021-03-16

2463 Design and proof-of-concept for targeted phage-based COVID-19 vaccination strategies with a streamlined cold-free supply chain

Staquicini, D. I.; Tang, F. H. F.; Markosian, C.; Yao, V. J.; Staquicini, F. I.; Dodero Rojas, E.; Contessoto, V. G.; Davis, D.; O'Brien, P.; Habib, N.; Smith, T. L.; Bruiners, N.; Sidman, R. L.; Gennaro, M. L.; Lattime, E. C.; Libutti, S. K.; Whitford, P. C.; Burley, S. K.; Onuchic, J. N.; Arap, W.; Pasqualini, R.

10.1101/2021.03.15.435496 — microbiology — Posted on 2021-03-16

2464 Cluster Analysis of SARS-CoV-2 Gene using Deep Learning Autoencoder: Gene Profiling for Mutations and Transitions

Miyake, J.; Sato, T.; Baba, S.; Nakamura, H.; Niioka, H.; Nakazawa, Y.

10.1101/2021.03.16.435601 — microbiology — Posted on 2021-03-16

2465 Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines

Walls, A. C.; Miranda, M. C.; Pham, M. N.; Schaefer, A.; Greaney, A.; Arunachalam, P. S.; Navarro, M.-J.; Tortorici, M. A.; Rogers, K.; O'Connor, M. A.; Shireff, L.; Ferrell, D. E.; Brunette, N.; Kepl, E.; Bowen, J. E.; Zepeda, S. K.; Starr, T.; Hsieh, C.-L.; Fiala, B.; Wrenn, S.; Pettie, D.; Sydeman, C.; Johnson, M.; Blackstone, A.; Ravichandran, R.; Ogohara, C.; Carter, L.; Tilles, S. W.; Rappuoli, R.; O'Hagan, D. T.; Van Der Most, R.; Van Voorhis, W. C.; McLellan, J. S.; Kleanthous, H.; Sheahan, T. P.; Fuller, D. H.; Villinger, F.; Bloom, J.; Pulendran, B.; Baric, R.; King, N. P.; Veesler,

10.1101/2021.03.15.435528 — immunology — Posted on 2021-03-16

2466 α-lipoic acid has the potential to normalize copper metabolism, which is dysregulated in Alzheimer's disease

Metsla, K.; Kirss, S.; Laks, K.; Sildnik, G.; Palgi, M.; Palumaa, T.; Tougu, V.; Palumaa, P.

10.1101/2021.03.15.435417 — neuroscience — Posted on 2021-03-16

2467 In Poetry, if Meter has to Help Memory, it Takes its Time

Andreetta, S.; Soldatkina, O.; Boboeva, V.; Treves, A.

10.1101/2021.03.14.435310 — neuroscience — Posted on 2021-03-16

2468 Simple morphometrics for predicting lordosis-induced deviations of body-shape in reared Gilthead seabream (Sparus aurata L.)

Fragkoulis, S.; Koumoundouros, G.

10.1101/2021.03.15.435302 — zoology — Posted on 2021-03-16

2469 Personalized sleep-wake patterns aligned with circadian rhythm relieve daytime sleepiness

Hong, J.; Choi, S. J.; Park, S. H.; Hong, H.; Booth, V.; Joo, E. Y.; Kim, J. K.

10.1101/2021.03.15.435366 — systems biology — Posted on 2021-03-16

2470 scite: a smart citation index that displays the context of citations and classifies their intent using deep learning

Nicholson, J. M.; Mordaunt, M.; Lopez, P.; Uppala, A.; Rosati, D.; Rodrigues, N. P.; Grabitz, P.; Rife, S.

10.1101/2021.03.15.435418 — scientific communication and education — Posted on 2021-03-16

2471 Reconstruction of Contemporary Human Stem Cell Dynamics with Oscillatory Molecular Clocks

Gabbutt, C.; Schenck, R. O.; Weisenberger, D.; Kimberley, C.; Berner, A.; Househam, J.; Lakatos, E.; Robertson-Tessi, M.; Martin, I.; Patel, R.; Clark, S.; Latchford, A.; Barnes, C. P.; Leedham, S. J.; Anderson, A. R.; Graham, T. A.; Shibata, D.

10.1101/2021.03.15.435426 — bioinformatics — Posted on 2021-03-16

2472 MCMICRO: A scalable, modular image-processing pipeline for multiplexed tissue imaging

Schapiro, D.; Sokolov, A.; Yapp, C.; Muhlich, J. L.; Hess, J.; Lin, J.-R.; Chen, Y.-A.; Nariya, M. K.; Baker, G. J.; Ruokonen, J.; Maliga, Z.; Jacobson, C. A.; Farhi, S. L.; Abbondanza, D.; McKinley, E. T.; Betts, C.; Regev, A.; Coffey, R. J.; Coussens, L. M.; Santagata, S.; Sorger, P. K.

10.1101/2021.03.15.435473 — bioinformatics — Posted on 2021-03-16

2473 CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids

Lo, M.; Sharir, A.; Paul, M. D.; Torosyan, H.; Agnew, C.; Raleigh, D. R.; Jura, N.; Klein, O. D.

10.1101/2021.03.15.435490 — biochemistry — Posted on 2021-03-16

2474 Comparative Genomics of two Inbred Lines of the Potato Cyst Nematode Globodera rostochiensis reveals disparate Effector Family-specific Diversification Patterns

van Steenbrugge, J. J. M.; van den Elsen, S.; Holterman, M.; Sterken, M. G.; Thorpe, P.; Goverse, A.; Smant, G.; Helder, J.

10.1101/2021.03.15.435409 — genomics — Posted on 2021-03-16

2475 tbg - a new file format for genomic data

Gerber, S.; Pfenninger, M.; Schell, T.; Schoennenbeck, P.

10.1101/2021.03.15.435393 — genomics — Posted on 2021-03-16

2476 Large Bi-Ethnic Study of Plasma Proteome Leads to Comprehensive Mapping of cis-pQTL and Models for Proteome-wide Association Studies

Zhang, J.; Dutta, D.; Köttgen, A.; Tin, A.; Schlosser, P.; Grams, M. E.; Harvey, B.; Yu, B.; Boerwinkle, E.; Coresh, J.; Chatterjee, N.

10.1101/2021.03.15.435533 — genetics — Posted on 2021-03-16

2477 Insights into the genetic architecture of complex traits in Napier grass (Cenchrus purpureus) and QTL regions governing forage biomass yield, water use efficiency and feed quality traits

Muktar, M. S.; Habte, E.; Teshome, A.; Assefa, Y.; Negawo, A. T.; Lee, K.-W.; Zhang, J.; Jones, C. S.

10.1101/2021.03.15.435454 — genetics — Posted on 2021-03-16

2478 Insights into the drivers of radiating diversification in biodiversity hotspots using Saussurea (Asteraceae) as a case

Zhang, X.; Landis, J. B.; Sun, Y.; Zhang, H.; Feng, T.; Lin, N.; Tiamiyu, B. B.; Huang, X.; Deng, T.; Wang, H.; Sun, H.

10.1101/2021.03.15.435394 — evolutionary biology — Posted on 2021-03-16

2479 The formal demography of kinship III: Kinship dynamics with time-varying demographic rates

Caswell, H.; Song, X.

10.1101/2021.03.15.435377 — ecology — Posted on 2021-03-16

2480 Alternative LC-MS/MS Platforms and Data Acquisition Strategies for Proteomic Genotyping of Human Hair Shafts

Goecker, Z. C.; Legg, K. M.; Salemi, M. R.; Herren, A. W.; Phinney, B. S.; McKiernan, H. E.; Parker, G. J.

10.1101/2021.03.15.435505 — molecular biology — Posted on 2021-03-16

2481 Natural Occurring Non-Synonymous Single Nucleotide Polymorphisms in Integrase and RNase H Regulate Assembly and Autoprocessing of HIV-1

Imamichi, T.; Bernbaum, J. G.; Laverdure, S.; Yang, J.; Chen, Q.; Highbarger, H.; Hao, M.; Sui, H.; Dewar, R.; Chang, W.; Lane, H. C.

10.1101/2021.03.15.435559 — microbiology — Posted on 2021-03-16

2482 Histone H3 Clipping is a novel signature of Human Neutrophil Extracellular Traps

Tilley, D. O.; Abuabed, U.; Zimny Arndt, U.; Schmid, M.; Florian, S.; Jungblut, P. R.; Brinkmann, V.; Herzig, A.; Zychlinsky, A.

10.1101/2021.03.15.434949 — immunology — Posted on 2021-03-16

2483 The role of ventromedial prefrontal cortex in reward valuation and future thinking during intertemporal choice

Ciaramelli, E.; De Luca, F.; Kwan, D.; Mok, J. N. Y.; Bianconi, F.; Knyagnytska, V.; Craver, C.; Green, L.; Myerson, J.; Rosenbaum, S.

10.1101/2021.03.15.435400 — neuroscience — Posted on 2021-03-16

Catlin, J.; Marziali, L. N.; Rein, B.; Yan, Z.; Feltri, M. L.; Schaner Tooley, C.

10.1101/2021.03.15.435479 — neuroscience — Posted on 2021-03-16

2485 Compulsive drinking is associated with neural activity patterns reflecting diminished behavioral control and enhanced seeking representations in dorsal medial prefrontal cortex

Timme, N.; Ma, B.; Linsenbardt, D. N.; Cornwell, E.; Galbari, T.; Lapish, C.

10.1101/2021.03.15.435169 — neuroscience — Posted on 2021-03-16

2486 Analogue representation of a spatial memory by ramp-like neural activity in retrohippocampal cortex

Tennant, S.; Hawes, I.; Clark, H.; Tam, W. K.; Hua, J.; Yang, W.; Gerlei, K.; Wood, E.; Nolan, M. F.

10.1101/2021.03.15.435518 — neuroscience — Posted on 2021-03-16

2487 Open source timed pressure control hardware and software for delivery of air mediated distensions in animal models

Patel, T.; Hendren, J.; Lee, N.; Mickle, A.

10.1101/2021.03.15.435466 — neuroscience — Posted on 2021-03-16

2488 Foxq2 determines blue cone identity in zebrafish

Ogawa, Y.; Shiraki, T.; Fukada, Y.; Kojima, D.

10.1101/2021.03.14.435350 — neuroscience — Posted on 2021-03-16

2489 Visuomotor information drives interference between the hands more than dynamic motor information during bimanual reaching

Desrochers, P. C.; Brunfeldt, A. T.; Kagerer, F. A.

10.1101/2021.03.15.435502 — neuroscience — Posted on 2021-03-16

2490 Imperfect integration: sensory congruency between multiple sources modulates selective decision-making processes

Krzeminski, D.; Zhang, J.

10.1101/2021.03.14.435307 — neuroscience — Posted on 2021-03-16

2491 Dynamic accumulation of a helper NLR at the plant-pathogen interface underpins pathogen recognition

Duggan, C.; Moratto, E.; Savage, Z.; Hamilton, E.; Adachi, H.; Wu, C.-H.; Leary, A. Y.; Tumtas, Y.; Rothery, S.; Maqbool, A.; Kamoun, S.; Bozkurt, T. O.

10.1101/2021.03.15.435521 — plant biology — Posted on 2021-03-16

2492 Assessing the Role of CaM's Linker Flexibility in Target Binding

Sun, B.; Kekenes-Huskey, P. M.

10.1101/2021.03.15.435522 — biophysics — Posted on 2021-03-16

2493 Codependency and mutual exclusivity for gene community detection from sparse single-cell transcriptome data

Nakajima, N.; Hayashi, T.; Fujiki, K.; Shirahige, K.; Akiyama, T.; Akutsu, T.; Nakato, R.

10.1101/2021.03.15.435370 — bioinformatics — Posted on 2021-03-16

2494 Predicting Cellular Drug Sensitivity using Conditional Modulation of Gene Expression

Connell, W.; Keiser, M. J.

10.1101/2021.03.15.435529 — bioinformatics — Posted on 2021-03-16

2495 Multi-omics Data Integration by Generative Adversarial Network

Ahmed, K. T.; Sun, J.; Yong, J.; Zhang, W.

10.1101/2021.03.13.435251 — bioinformatics — Posted on 2021-03-16

2496 BIONIC: Biological Network Integration using Convolutions

Forster, D. T.; Boone, C.; Bader, G.; Wang, B.

10.1101/2021.03.15.435515 — bioinformatics — Posted on 2021-03-16

2497 dGPredictor: Automated fragmentation method for metabolic reaction free energy prediction and de novo pathway design

Wang, L.; Upadhyay, V.; Maranas, C. D.

10.1101/2021.03.15.434460 — bioinformatics — Posted on 2021-03-16

2498 overlappingCGM: Automatic detection and analysis of overlapping co-expressed gene modules

Nguyen, Q.-H.; Le, D.-H.

10.1101/2021.03.15.435373 — bioinformatics — Posted on 2021-03-16

2499 Sub-second multi-channel magnetic control of select neural circuits in behaving flies

Sebesta, C.; Torres, D.; Wang, B.; Li, Z.; Duret, G.; Jiang, K.; Xiao, Z.; Zhang, Q.; Colvin, V.; Goetz, S. M.; Peterchev, A. V.; Dierick, H.; Bao, G.; Robinson, J. T.

10.1101/2021.03.15.435264 — bioengineering — Posted on 2021-03-16

2500 A gut-restricted lithocholic acid analog as an inhibitor of gut bacterial bile salt hydrolases

Adhikari, A. A.; Ramachandran, D.; Chaudhari, S. N.; Powell, C. E.; McCurry, M. D.; Banks, A. S.; Devlin, A. S.

10.1101/2021.03.15.435552 — biochemistry — Posted on 2021-03-16

2501 Identification of Japanese Encephalitis Virus Genotype V and Other Mosquito-borne Viruses in Camp Humphreys, Republic of Korea, using Metagenomic Analysis

Sanborn, M. A.; McGuckin Wuertz, K.; Heung-Chul, K.; Yang, Y.; Li, T.; Pollett, S. D.; Jarman, R. G.; Maljkovic Berry, I.; Klein, T. A.; Hang, J.

10.1101/2021.03.15.435489 — genomics — Posted on 2021-03-16

2502 Cross-species prediction of essential genes in insects through machine learning and sequence-based attributes

Marques de Castro, G.; Hastenreiter, Z.; Augusto Silva Monteiro, T.; Lobo, F. P.

10.1101/2021.03.15.433440 — genomics — Posted on 2021-03-16

2503 A NEW CASE OF DIPLOIDY WITHIN A HAPLOID GENUS OF ENTOMOPATHOGENIC FUNGI

Nielsen, K. N.; Salgado, J. F. M.; Natsopoulou, M. E.; Stajich, J. E.; De Fine Licht, H. H.

10.1101/2021.03.15.435421 — genomics — Posted on 2021-03-16

2504 Population structure of Drosophila suzukii and signals of multiple invasions into the continental United States

Lewald, K. M.; Abrieux, A.; Wilson, D. A.; Lee, Y.; Conner, W. R.; Andreazza, F.; Beers, E. H.; Burrack, H. J.; Daane, K. M.; Diepenbrock, L.; Drummond, F. A.; Fanning, P. D.; Gaffney, M. T.; Hesler, S. P.; Ioriatti, C.; Isaacs, R.; Little, B. A.; Loeb, G. M.; Miller, B.; Nava, D. E.; Rendo, D.; Sial, A. A.; da Silva, C. B.; Stockton, D. G.; Van Timmeren, S.; Wallingford, A.; Walton, V. M.; Wang, X.; Zhao, B.; Zalom, F. G.; Chiu, J. C.

10.1101/2021.03.14.435345 — genomics — Posted on 2021-03-16

2505 Genomic Surveillance of Acinetobacter baumannii in the Philippines, 2013-2014

Chilam, J.; Argimon, S.; Limas, M. T.; Masim, M. L.; Gayeta, J. M.; Lagrada, M. L.; Olorosa, A. M.; Cohen, V.; Hernandez, L. T.; Jeffrey, B.; Abu-Dahab, K.; Hufano, C. M.; Sia, S. B.; Holden, M. T. G.; Stelling, J.; Aanensen, D. M.; Carlos, C. C.; Philippines Antimicrobial Resistance Surveillance Program,

10.1101/2021.03.15.435482 — genomics — Posted on 2021-03-16

2506 Super interactive promoters provide insight into cell type-specific regulatory networks in blood lineage cell types

Lagler, T. M.; Yang, Y.; Harigaya, Y.; Sankaran, V. G.; Hu, M.; Reiner, A. P.; Raffield, L. M.; Wen, J.; Li, Y.

10.1101/2021.03.15.435494 — genetics — Posted on 2021-03-16

2507 Genome assembly of the maize inbred line A188 provides a new reference genome for functional genomics

Ge, F.; Qu, J.; Liu, P.; Pan, L.; Zou, C.; Yuan, G.; Yang, C.; Gao, S.; Pan, G.; Huang, J.; Ma, L.; Shen, Y.

10.1101/2021.03.15.435372 — genetics — Posted on 2021-03-16

2508 Allele frequency divergence reveals ubiquitous influence of positive selection in Drosophila

Bertram, J.

10.1101/2021.03.15.435474 — evolutionary biology — Posted on 2021-03-16

2509 Spatial and temporal assessment of the risk associated to bacteria in recreational waters of a large South American Reservoir

Gangi, D.; Frau, D.; Drozd, A.; Bordet, F.; Andrade, S.; Bazzalo, M.; DE TEZANOS PINTO, P.

10.1101/2021.03.15.435485 — ecology — Posted on 2021-03-16

2510 Early Spring Snowmelt and Summer Droughts Strongly Impair the Resilience of Key Microbial Communities in Subalpine Grassland Ecosystems

Hafeez, F.; Bernard, L.; Clement, J.-C.; Poly, F.; Pommier, T.

10.1101/2021.03.15.435477 — ecology — Posted on 2021-03-16

2511 Leakiness at the human-animal interface in Southeast Asia and implications for the spread of antibiotic resistance

Nadimpalli, M. L.; Stegger, M.; Viau, R.; Yith, V.; de Lauzanne, A.; Sem, N.; Borand, L.; Huynh, B.-t.; Brisse, S.; Passet, V.; Overballe-Petersen, S.; Aziz, M.; Gouali, M.; Jacobs, J.; Phe, T.; Hungate, B. A.; Leshyk, V. O.; Pickering, A. J.; Gravey, F.; Liu, C. M.; Johnson, T. J.; Le Hello, S.; Price, L. B.

10.1101/2021.03.15.435134 — ecology — Posted on 2021-03-16

2512 Functionally distinct T-helper cell phenotypes predict resistance to different types of parasites in a wild mammal

Corripio-Miyar, Y.; Hayward, A.; Lemon, H.; Sweeny, A. R.; Bal, X.; Kenyon, F.; Pilkington, J. G.; Pemberton, J. M.; Nussey, D. H.; McNeilly, T. N.

10.1101/2021.03.15.435455 — ecology — Posted on 2021-03-16

2513 The brown algae Saccharina japonica and Sargassum horneri exhibit species-specific responses to synergistic stress of ocean acidification and eutrophication

Liu, Y.; Cao, J.; Chu, Y.; Liu, Y.; Wang, Q.; Gong, Q.; Li, J.

10.1101/2021.03.15.435540 — ecology — Posted on 2021-03-16

2514 Machine learning methods trained on simple models can predict critical transitions in complex natural systems

Dev, S.; Sidheekh, S.; Clements, C. F.; Krishnan, N. C.; Dutta, P. S.

10.1101/2021.03.15.435556 — ecology — Posted on 2021-03-16

2515 Methylation studies in Peromyscus: aging, altitude adaptation, and monogamy

Horvath, S.; Haghani, A.; Zoller, J. A.; Naderi, A.; Soltanmohammadi, E.; Farmaki, E.; Kaza, V.; Chatzistamou, I.; Kiaris, H.

10.1101/2021.03.15.435544 — developmental biology — Posted on 2021-03-16

2516 A BI-1 mediated cascade improves redox homeostasis during thermal stress and prevents oxidative damage in a preconditioned reef-building coral

Majerova, E.; Drury, C.

10.1101/2021.03.15.435543 — cell biology — Posted on 2021-03-16

2517 An integrative transcriptional logic model of hepatic insulin resistance

KITAMOTO, T.; Kuo, T.; Okabe, A.; Kaneda, A.; Accili, D.

10.1101/2021.03.15.435438 — molecular biology — Posted on 2021-03-16

2518 Antibiotic Resistance in Bacillus-based Biopesticide Products

Kaze, M.; Sistrom, M.; Brooks, L.

10.1101/2021.03.15.435560 — microbiology — Posted on 2021-03-16

2519 Amotosalen is a bacterial multidrug efflux pump substrate potentially affecting its pathogen inactivation activity

Green, A. B.; Zulauf, K. E.; Truelson, K. A.; Chiaraviglio, L.; Cui, M.; Zhang, Z.; Ware, M. P.; Flegel, W. A.; Haspel, R. L.; Yu, E. W.; Kirby, J. E.

10.1101/2021.03.15.435562 — microbiology — Posted on 2021-03-16

2520 Cytotoxic efficiency of human CD8+ T cell memory subtypes

Knörck, A.; Schwär, G.; Alansary, D.; Thurner, L.; Hoth, M.; Schwarz, E. C.

10.1101/2021.03.15.435339 — immunology — Posted on 2021-03-16

2521 Responding kinetic of B-cell receptor repertoire to the Toll-like receptor 7/8 stimulation in non-human primates

Wang, S.; Mandl, J.; Feinberg, M.; Citron, M.; Saksena, N. K.; Luo, L.; Li, Z.; Zhu, Y.; Li, T.; Nie, C.; Zhang, X.; Liu, Y.; Liu, X.; Wang, I.-M.; Zhang, W.

10.1101/2021.03.15.435360 — immunology — Posted on 2021-03-16

2522 Tissue environment, not ontogeny, defines intestinal intraepithelial T lymphocytes

Brenes, A. J.; Vandereyken, M.; James, O. J.; Hukelmann, J.; Spinelli, L.; Lamond, A. I.; Swamy, M.

10.1101/2021.03.15.435419 — immunology — Posted on 2021-03-16

2523 The inflammasome-activated cytokine IL-1 is targeted for ubiquitylation and proteasomal degradation to limit its inflammatory potential

Vijayaraj, S.; Feltham, R.; Rashidi, M.; Frank, D.; Liu, Z.; Simpson, D.; Ebert, G.; Vince, A.; Herold, M. J.; Kueh, A. J.; Pearson, J.; Dagley, L.; Murphy, J. M.; Webb, A. I.; Lawlor, K. E.; Vince, J. E.

10.1101/2021.03.15.435390 — immunology — Posted on 2021-03-16

2524 Analysis of M4 transmembrane domains in NMDA receptor function: a negative allosteric modulation site at the GluN1 M4 is determining the efficiency of neurosteroid modulation

Langer, K.; Mueller-Laengle, A.; Wempe, J.; Laube, B.

10.1101/2021.03.15.435138 — neuroscience — Posted on 2021-03-16

2525 Time series analysis of trial-to-trial variability of MEG power spectrum during rest state, unattented listening and frequency-modulated tones classification

Kipinski, L.; Kordecki, W.

10.1101/2021.03.15.435429 — neuroscience — Posted on 2021-03-16

2526 Spontaneous Eye Blink Rate during the Working Memory Delay Period Predicts Task Performance

Ortega, J.; Reichert Plaska, C.; Gomes, B. A.; Ellmore, T. M.

10.1101/2021.03.15.435433 — neuroscience — Posted on 2021-03-16

2527 Retinal factors of visual sensitivity in the human fovea

Domdei, N.; Reiniger, J. L.; Holz, F. G.; Harmening, W. M.

10.1101/2021.03.15.435507 — neuroscience — Posted on 2021-03-16

2528 Open Data Commons for Preclinical Traumatic Brain Injury Research: Empowering Data Sharing and Big Data Analytics

Chou, A. C.; Torres-Espin, A.; Huie, J. R.; Krukowski, K.; Lee, S.; Nolan, A.; Guglielmetti, C.; Hawkins, B. E.; Chaumeil, M. M.; Manley, G. T.; Beattie, M. S.; Bresnahan, J. C.; Martone, M. E.; Grethe, J. S.; Rosi, S.; Ferguson, A. R.

10.1101/2021.03.15.435178 — neuroscience — Posted on 2021-03-16

2529 Changing in the hierarchical organization of local information dynamics during motor decision in the premotor cortex of primates

Bardella, G.; Giarrocco, F.; Andujar, M.; Brunamonti, E.; Pani, P.; Ferraina, S.

10.1101/2021.03.15.435381 — neuroscience — Posted on 2021-03-16

2530 Bump attractor dynamics underlying stimulus integration in perceptual estimation tasks

Esnaola-Acebes, J. M.; Roxin, A.; Wimmer, K.

10.1101/2021.03.15.434192 — neuroscience — Posted on 2021-03-16

2531 Altered Effective Connectivity in Sensorimotor Cortices: a Novel Signature of Severity and Clinical Course in Depression

Ray, D.; Bezmaternykh, D.; Mel'nikov, M.; Friston, K. J.; Das, M.

10.1101/2021.03.14.435324 — neuroscience — Posted on 2021-03-16

2532 Causal inference on microbiome-metabolome relations via in silico in vivo association pattern analyses

Hertel, J.; Heinken, A.; Thiele, I.

10.1101/2021.03.15.435397 — systems biology — Posted on 2021-03-16

2533 SPIRO-the automated Petri plate imaging platform designed by biologists, for biologists

Ohlsson, J. A.; Leong, J. X.; Elander, P. H.; Dauphinee, A. N.; Ballhaus, F.; Johansson, J.; Lommel, M.; Hofmann, G.; Betner, S.; Sandgren, M.; Schumacher, K.; Bozhkov, P. V.; Minina, A. E. A.

10.1101/2021.03.15.435343 — plant biology — Posted on 2021-03-16

2534 Deficiency of peroxisomal L-bifunctional protein (EHHADH) causes male-specific kidney hypertrophy and proximal tubular injury in mice

Ranea-Robles, P.; Portman, K.; Bender, A.; Lee, K.; He, J. C.; Mulholland, D. J.; Argmann, C.; Houten, S. M.

10.1101/2021.03.14.435187 — physiology — Posted on 2021-03-16

2535 Genome-wide association study of gastric cancer- and duodenal ulcer-derived Helicobacter pylori strains reveals discriminatory amino acid differences and novel oncoprotein candidates

Yahara, K.; Tuan, V. P.; Dung, H. D. Q.; Binh, T. T.; Tung, P. H.; Tri, T. D.; Thuan, N. P. M.; Khien, V. V.; Trang, T. T. H.; Phuc, B. H.; Tshibangu-Kabamba, E.; Matsumoto, T.; Akada, J.; Suzuki, R.; Okimoto, T.; Kodama, M.; Murakami, K.; Yano, H.; Fukuyo, M.; Takahashi, N.; Kato, M.; Nishiumi, S.; Azuma, T.; Ogura, Y.; Hayashi, T.; Toyoda, A.; Kobayashi, I.; Yamaoka, Y.

10.1101/2021.03.15.435401 — physiology — Posted on 2021-03-16

2536 Broccoli sprout Sulforaphane affected hemodynamics and aorta myogenic spontaneous rhythmic contraction in sanitized water uptake mice

Li, L.; Gao, L.; Wang, T.; He, T.; Li, J.; Suwardi, R. K.; Xu, X.; Wang, Y.

10.1101/2021.03.15.435382 — physiology — Posted on 2021-03-16

2537 Late Anisian microbe-metazoan build-ups ('stromatolites') in the Germanic Basin -- aftermath of the Permian -- Triassic Crisis

Pei, Y.; Duda, J.-p.; Schoenig, J.; Luo, C.; Reitner, J.

10.1101/2021.03.15.435468 — paleontology — Posted on 2021-03-16

2538 Indication-specific tumor evolution and its impact on neoantigen targeting and biomarkers for individualized cancer immunotherapies

Lo, A. A.; Wallace, A.; Oreper, D.; Lounsbury, N.; Havnar, C.; Pechuan-Jorge, X.; Wu, T. D.; Bourgon, R.; Jones, R.; Krogh, K.; Yang, G.-Y.; Zill, O. A.

10.1101/2021.03.15.434617 — cancer biology — Posted on 2021-03-16

2539 Using machine learning and big data to explore the drug resistance landscape in HIV

Blassel, L.; Tostevin, A.; Villabona-Arenas, C. J.; Peeters, M.; Hue, S.; Gascuel, O.

10.1101/2021.03.15.435398 — bioinformatics — Posted on 2021-03-16

2540 OCD.py - Characterizing immunoglobulin inter-domain orientations

Hoerschinger, V. J.; Fernandez-Quintero, M. L.; Waibl, F.; Kraml, J.; Bujotzek, A.; Georges, G.; Liedl, K. R.

10.1101/2021.03.15.435379 — bioinformatics — Posted on 2021-03-16

2541 Tracing evolution history of 100 whole genome sequences of diffuse stem brain tumor

Zou, L.

10.1101/2021.03.14.435347 — genomics — Posted on 2021-03-16

2542 Ecological correlates of gene family size: the draft genome of the redheaded pine sawfly Neodiprion lecontei

Vertacnik, K.; Herrig, D.; Godfrey, R. K.; Hill, T.; Geib, S.; Unckless, R.; Nelson, D.; Linnen, C. R.

10.1101/2021.03.14.435331 — evolutionary biology — Posted on 2021-03-16

2543 Fmrp regulates oligodendrocyte lineage cell specification and differentiation

Doll, C. A.; Scott, K.; Appel, B.

10.1101/2021.03.16.435661 — developmental biology — Posted on 2021-03-16

2544 Persistent ventricle partitioning in the adult zebrafish heart

Pfefferli, C.; Moran, H. R.; Felker, A.; Mosimann, C.; Jazwinska, A.

10.1101/2021.03.16.435658 — developmental biology — Posted on 2021-03-16

2545 Size and shape regional differentiation during the development of the spine in the nine-banded armadillo (Dasypus novemcinctus)

Oliver, J.; Jones, K.; Pierce, S.; Hautier, L.

10.1101/2021.03.16.435620 — developmental biology — Posted on 2021-03-16

2546 A high throughput SEC23 functional interaction screen reveals a role for focal adhesion and extracellular matrix signalling in the regulation of COPII subunit SEC23A

Jung, J.; Pepperkok, R.; Khan, M. M.; Landry, J.; Halavatyi, A.; Reiss, M.; Machado, P.

10.1101/2021.03.16.435679 — cell biology — Posted on 2021-03-16

2547 Inhibition of the ubiquitin-proteasome system by a bioactivatable compound

Giovannucci, T. A.; Salomons, F.; Haraldsson, M.; Elfman, L.; Wickstrom, M.; Young, P.; Lundback, T.; Eirich, J.; Altun, M.; Jafari, R.; Gustavsson, A.-L.; Johnson, J. I.; Dantuma, N.

10.1101/2021.03.16.435589 — cell biology — Posted on 2021-03-16

2548 Inducible expression of Oct-3/4 reveals synergy with Klf4 in targeting Cyclin A2 to enhance proliferation during early reprogramming

Zaveri, L.; Dhawan, J.

10.1101/2021.03.16.435687 — cell biology — Posted on 2021-03-16

2549 VASP mediated actin dynamics activate and recruit a filopodia myosin

Arthur, A. L.; Crawford, A.; Houdusse, A.; Titus, M. A.

10.1101/2021.03.16.435667 — cell biology — Posted on 2021-03-16

2550 Stiffness Regulates Intestinal Stem Cell Fate

He, S.; Peng, L.; Kang, W.; Cheung, P.; Xu, T.; Mana, M.; Park, C. Y.; Wang, H.; Imada, S.; Russell, J. O.; Wang, J.; Wang, R.; Zhou, Z.; Chetal, K.; Stas, E.; Mohad, V.; Halasi, M.; Bruun-Rasmussen, P.; Sadreyev, R. I.; Adini, I.; Breault, D.; Hodin, R. A.; Zhang, Y.; Camargo, F.; Yilmaz, O. H.; Fredberg, J. J.; Saeidi, N.

10.1101/2021.03.15.435410 — cell biology — Posted on 2021-03-16

2551 Genetic dissection of glutamatergic neuron subpopulations and developmental trajectories in the cerebral cortex

Matho, K. S. H.; Huilgol, D.; Galbavy, W.; He, M.; Kim, G.; An, X.; Lu, J.; Wu, P.; Di Bella, D. J.; Shetty, A. S.; Palaniswamy, R.; Hatfield, J.; Raudales, R.; Narasimhan, A.; Gamache, E.; Levine, J. M.; Tucciarone, J.; Szelenyi, E.; Harris, J. A.; Mitra, P. P.; Osten, P.; Arlotta, P.; Huang, Z. J.

10.1101/2020.04.22.054064 — neuroscience — Posted on 2021-03-16

2552 Arpin regulates migration persistence by interacting with both tankyrases and the Arp2/3 complex

Simanov, G.; Dang, I.; Fokin, A. I.; Oguievetskaia, K.; Campanacci, V.; Cherfils, J.; Gautreau, A. M.

10.1101/2021.03.16.435563 — cell biology — Posted on 2021-03-16

2553 Alignment and Integration of Spatial Transcriptomics Data

Zeira, R.; Land, M.; Raphael, B.

10.1101/2021.03.16.435604 — bioinformatics — Posted on 2021-03-16

2554 Morphological principles of neuronal mitochondria

10.1101/2021.03.15.435547 — neuroscience — Posted on 2021-03-16

2555 Evolution of two-component quorum sensing systems

Giannakara, M.; Koumandou, V. L.

10.1101/2020.11.15.381053 — evolutionary biology — Posted on 2021-03-16

2556 Genetic dissection of glutamatergic neuron subpopulations and developmental trajectories in the cerebral cortex

10.1101/2020.04.22.054064 — neuroscience — Posted on 2021-03-16

2557 A model of Ponto-Geniculo-Occipital waves supports bidirectional control of cortical plasticity across sleep-stages

Shao, K.; Ramirez Villegas, J. F.; Logothetis, N. K.; Besserve, M.

10.1101/2021.03.16.432817 — neuroscience — Posted on 2021-03-16

2558 Encoding innate ability through a genomic bottleneck

Koulakov, A.; Shuvaev, S.; Zador, A.

10.1101/2021.03.16.435261 — neuroscience — Posted on 2021-03-16

2559 Co-translational folding of the first transmembrane domain of ABC-transporter CFTR is supported by assembly with the first cytosolic domain

Kleizen, B.; van Willigen, M.; Mijnders, M.; Peters, F. M.; Grudniewska, M. K.; Hillenaar, T. M.; Thomas, A. S.; Kooijman, L.; Peters, K. W.; Frizzell, R.; van der Sluijs, P.; Braakman, I.

10.1101/2020.12.19.423590 — biochemistry — Posted on 2021-03-16

2560 An LR framework incorporating sensitivity analysis to model multiple direct and secondary transfer events on skin surface

Gill, P.; Bleka, O.; Roseth, A.; Fonnelop, A. E.

10.1101/2021.02.08.429904 — genetics — Posted on 2021-03-16

2561 The anterior Hox gene ceh-13 and elt-1/GATA activate the posterior Hox genes nob-1 and php-3 to specify posterior lineages in the C. elegans embryo

Murray, J. I.; Preston, E.; Crawford, J. P.; Rumley, J. D.; Amom, P.; Anderson, B. D.; Sivaramakrishnan, P.; Patel, S. D.; Bennett, B. A.; Lavon, T. D.; Peng, F.; Zacharias, A. L.

10.1101/2021.02.09.430385 — genetics — Posted on 2021-03-16

2562 Mosaic vaccination: how distributing different vaccines across a population could improve epidemic control

McLeod, D. V.; Wahl, L. M.; Mideo, N.

10.1101/2020.11.22.393124 — evolutionary biology — Posted on 2021-03-16

2563 Diversification of Transcription Factor NF-κB in Protists

Williams, L. M.; Sridhar, S.; Samaroo, J.; Adindu, E. K.; Addanki, A.; BB522 Molecular Biology Laboratory, ; Aguirre Carrion, P. J.; DiRusso, C. J.; Rodriguez-Sastre, N.; Siggers, T.; Gilmore, T. D.

10.1101/2021.03.15.435342 — cell biology — Posted on 2021-03-16

2564 Droplet-based single cell RNA sequencing of bacteria identifies known and previously unseen cellular states

McNulty, R. A.; Sritharan, D.; Liu, S.; Hormoz, S.; Rosenthal, A. Z.

10.1101/2021.03.10.434868 — microbiology — Posted on 2021-03-16

2565 Neuronal cascades shape whole-brain functional dynamics at rest

Rabuffo, G.; Fousek, J.; Bernard, C.; Jirsa, V.

10.1101/2020.12.25.424385 — neuroscience — Posted on 2021-03-16

2566 The developing brain structural and functional connectome fingerprint

10.1101/2021.03.08.434357 — neuroscience — Posted on 2021-03-16

2567 Use of lignocellulosic residue from 2G ethanol production to enhance methane production through co-digestion

Volpi, M. P. C.; de Paiva, L. B. B.; Mockaitis, G.; Rabelo, S. C.; Franco, T. T.; Moraes, B. d. S.

10.1101/2021.02.19.432018 — bioengineering — Posted on 2021-03-16

2568 A normative account of confirmation bias during reinforcement learning

Lefebvre, G.; Summerfield, C.; Bogacz, R.

10.1101/2020.05.12.090134 — animal behavior and cognition — Posted on 2021-03-16

2569 Temperature predicts the maximum tree-species richness and water and frost shape the residual variation

Segovia, R. A.

10.1101/836338 — ecology — Posted on 2021-03-16

2570 A chemogenetic platform for controlling plasma membrane signaling and synthetic signal oscillation

Hatano, Y.; Suzuki, S.; Nakamura, A.; Yoshii, T.; Atsuta-Tsunoda, K.; Aoki, K.; Tsukiji, S.

10.1101/2021.03.16.435568 — synthetic biology — Posted on 2021-03-16

2571 Computational Design and Analysis of Modular Cells for Large Libraries of Exchangeable Product Synthesis Modules

Garcia, S.; Trinh, C. T.

10.1101/2021.03.15.435526 — synthetic biology — Posted on 2021-03-16

2572 The regenerating skeletal muscle niche guides muscle stem cell self-renewal

Cutler, A. A.; Pawlikowski, B.; Wheeler, J. R.; Dalla Betta, N.; Antwine, T.; O'Rourke, R.; Jones, K.; Olwin, B. B.

10.1101/635805 — cell biology — Posted on 2021-03-16

2573 A biomechanical comparison of the jerk, back jerk, vertical jump and jump squat.

Liu, J.

10.1101/2021.03.15.435446 — scientific communication and education — Posted on 2021-03-15

2574 Evaluation of substrate composition and exogenous hormone application on vegetative propagule rooting success of essential oil hemp (Cannabis sativa L.)

Campbell, S. M.; Anderson, S. L.; Brym, Z.; Pearson, B. J.

10.1101/2021.03.15.435449 — plant biology — Posted on 2021-03-15

2575 Low-Cost, Modular Modification to a Desktop 3D Printer for General Purpose Gel/Paste Extrusion & Direct Ink Writing

Leech, D. J.; Lightfoot, S.; Huson, D.; Stratakos, A. C.

10.1101/2021.03.10.434735 — bioengineering — Posted on 2021-03-16

2576 Structural basis for late maturation steps of the human mitoribosomal large subunit

Cipullo, M.; Valentin Gese, G.; Khawaja, A.; Hallberg, M.; Rorbach, J.

10.1101/2021.03.15.435084 — biochemistry — Posted on 2021-03-16

2577 Inference of the worldwide invasion routes of the pinewood nematode Bursaphelenchus xylophilus using approximate Bayesian computation analysis

Mallez, S.; Castagnone, C.; Lombaert, E.; Castagnone-Sereno, P.; Guillemaud, T.

10.1101/452326 — genetics — Posted on 2021-03-16

2578 Intra and inter-annual climatic conditions have stronger effect than grazing intensity on root growth of permanent grasslands

Picon-Cochard, C.; Vassal, N.; Martin, R.; Herfurth, D.; Note, P.; Louault, F.

10.1101/2020.08.23.263137 — ecology — Posted on 2021-03-16

2579 Determinants of different facets of beta diversity in Mediterranean marine amphipods

Bellisario, B.; Camisa, F.; Abbattista, C.; Cimmaruta, R.

10.1101/2020.10.30.360677 — ecology — Posted on 2021-03-16

2580 Traction forces exerted by the developing optic cup mediate cell movements and axon extension in the olfactory placode

Monnot, P.; Gangatharan, G.; Baraban, M.; Pottin, K.; Cabrera, M.; Bonnet, I.; Breau, M. A.

10.1101/2021.03.15.435408 — developmental biology — Posted on 2021-03-16

2581 Modeling the bistable transition between cell phenotypes during limb precartilage condensation

Glimm, T.; Kazmierczak, B.; Cui, C.; Newman, S. A.; Bhat, R.

10.1101/2021.03.15.435301 — developmental biology — Posted on 2021-03-16

2582 Epiblast morphogenesis is controlled by selective mRNA decay triggered by LIN28A relocation

Modic, M.; los Mozos, I. R. d.; Steinhauser, S.; van Genderen, E.; Schirge, S.; Bergant, V.; Ryan, J.; Mulholland, C. B.; Lee, F. C. Y.; Faraway, R.; Klobucar, T.; Merl-Pham, J.; Hauck, S. M.; Drukker, M.; Bultmann, S.; Leonhardt, H.; Lickert, H.; Luscombe, N. M.; ten Berge, D.; Ule, J.

10.1101/2021.03.15.433780 — developmental biology — Posted on 2021-03-16

2583 DNA methylation clocks show slower progression of aging in naked mole-rat queens

Horvath, S.; Haghani, A.; Macoretta, N.; Ablaeva, J.; Zoller, J. A.; Li, C. Z.; Zhang, J.; Takasugi, M.; Zhao, Y.; Rydkina, E.; Zhang, Z.; Emmrich, S.; Raj, K.; Seluanov, A.; Faulkes, C. G.; Gorbunova, V.

10.1101/2021.03.15.435536 — developmental biology — Posted on 2021-03-16

2584 Cytoplasmic forces functionally reorganize nuclear condensates in oocytes

Al Jord, A.; Letort, G.; Eichmuller, A.; Chanet, S.; HUYNH, J.-R.; Gov, N.; Voituriez, R.; Terret, M.-E.; Verlhac, M.-H.

10.1101/2021.03.15.434387 — cell biology — Posted on 2021-03-16

2585 Implications of cholesterol and sphingomyelin in STING phosphorylation by TBK1

Takahashi, K.; Niki, T.; Ogawa, E.; Fumika, K.; Nishioka, Y.; Sawa, M.; Arai, H.; Mukai, K.; Taguchi, T.

10.1101/2021.03.15.435550 — cell biology — Posted on 2021-03-16

2586 A Bioinformatic and Empiric Exploration of Prokaryotic Argonautes as Novel Programmable Endonuclease Systems

Salic, S.; Sieber, A.; Barbaria, S.; Vasilyev, A.; Papadimou, E.; Milosavljevic, N.; Klapholz, B.; Sivapalan, R.; Collingwood, T.; Henley, T.; Choudhry, M.; Burckstummer, T.

10.1101/2021.03.15.435463 — molecular biology — Posted on 2021-03-15

2587 Vtc5 is localized to the vacuole membrane by the conserved AP-3 complex to regulate polyphosphate synthesis in budding yeast

Bentley-DeSousa, A.; Downey, M.

10.1101/2021.03.15.434853 — molecular biology — Posted on 2021-03-16

2588 Cross-species evolutionary rewiring in the enteric bacterium Campylobacter

Taylor, A. J.; Meric, G.; Yahara, K.; Pascoe, B.; Mageiros, L.; Mourkas, E.; Calland, J. K.; Puranen, S.; Hitchings, M. D.; Bayliss, S. C.; Jolley, K. A.; Kobras, C. M.; Williams, N. J.; van Vliet, A. H.; Parkhill, J.; Maiden, M. C.; Corander, J.; Falush, D.; Didelot, X.; Kelly, D. J.; Sheppard, S. K.

10.1101/2021.03.15.435406 — microbiology — Posted on 2021-03-15

2589 The PfAP2-HS transcription factor protects malaria parasites from febrile temperatures

Tinto-Font, E.; Michel-Todo, L.; Russell, T. J.; Casas-Vila, N.; Conway, D. J.; Bozdech, Z.; Llinas, M.; Cortes, A.

10.1101/2021.03.15.435375 — microbiology — Posted on 2021-03-15

2590 Shed the light on virus: virucidal effects of 405 nm visible light on SARS-CoV-2 and influenza A virus.

Yahnke, C. J.; Rathnasinghe, R. J.; Garcia-Sastre, A.

10.1101/2021.03.14.435337 — microbiology — Posted on 2021-03-15

2591 Primary brain cell infection by Toxoplasma gondii reveals the extent and dynamics of parasite differentiation and impact on neuron biology.

Mouveaux, T.; Roger, E.; Gueye, A.; Eysert, F.; Huot, L.; Grenier-Boley, B.; Lambert, J.-C.; GISSOT, M.

10.1101/2021.03.15.435467 — microbiology — Posted on 2021-03-15

2592 An ecological basis for dual genetic code expansion in marine deltaproteobacteria

Kivenson, V.; Paul, B. G.; Valentine, D. L.

10.1101/2021.03.15.435355 — microbiology — Posted on 2021-03-15

2593 High Content and High Throughout Phenotypic Assay for the Hourly Resolution of the Malaria Parasite Erythrocytic Cycle

Bell, D.; Ridewood, S.; Patel, A. P.; Lee, S. H.; Chang, Y.-T.; Deu, E.

10.1101/2021.03.15.434938 — microbiology — Posted on 2021-03-15

2594 Borrelia infection in rodent host has dramatic effects on the microbiome of ticks

Hamilton, P.; Maluenda, E.; Sarr, A.; Belli, A.; Hurry, G.; Duron, O.; Plantard, O.; Voordouw, M. J.

10.1101/2021.03.15.435198 — microbiology — Posted on 2021-03-15

2595 A simple coloring method to distinguish colonies of the yeasts Lachancea thermotolerans and Saccharomyces cerevisiae on agar media

Melkonian, C.; Haver, A.; Hellmuth, A.-S.; Kalmoua, Z.; Wagner, M.; Mendoza, S. N.; Molenaar, D.

10.1101/2021.03.15.434753 — microbiology — Posted on 2021-03-15

2596 Antibody evasion by the Brazilian P.1 strain of SARS-CoV-2

Dejnirattisai, W.; Zhou, D.; Supasa, P.; Liu, C.; Mentzer, A. J.; Ginn, H.; Zhao, Y.; Duyvesteyn, H. M. E.; Tuekprakhon, A.; Nutalai, R.; Wang, B.; Paesen, G. C.; Lopez-Camacho, C.; Slon-Campos, J.; Walter, T.; Skelly, D.; Clemens, S. A. C.; Naveca, F. G.; Nascimento, V.; Nascimento, F.; da Costa, C. F.; Dold, C.; Levin, R.; Dong, T.; Pollard, A. J.; Knight, J. C.; Crook, D.; Lambe, T.; Clutterbuck, E.; Bibi, S.; Flaxman, A.; Bittaye, M.; Belij-Rammerstorfer, S.; Gilbert, S.; Carroll, M. W.; Klenerman, P.; Barnes, E.; Dunachie, S. J.; Paterson, N. G.; Williams, M. A.; Hall, D. R.; Hulswit, R.;

10.1101/2021.03.12.435194 — microbiology — Posted on 2021-03-15

2597 Arginine induced Streptococcus gordonii biofilm detachment using a novel rotating-disc rheometry method

Gloag, E. S.; Wozniak, D. J.; Wolf, K. L.; Masters, J. G.; Amorin Daep, C.; Stoodley, P.

10.1101/2021.03.15.435500 — microbiology — Posted on 2021-03-15

2598 Trans -cinnamaldehyde attenuates Enterococcus faecalis virulence and inhibits biofilm formation

Ali, I. A. A.; Matinlinna, J.; Levesque, C.; Neelakantan, P.

10.1101/2021.03.15.435450 — microbiology — Posted on 2021-03-15

2599 Paratransgenic manipulation of tsetse miR275 alters the physiological homeostasis of the flys midgut environment

Yang, L.; Weiss, B.; Williams, A. E.; Aksoy, E.; de Silva Orfano, A.; Son, J. H.; Wu, Y.; Vigneron, A.; Karakus, M.; Aksoy, S.

10.1101/2021.03.15.435453 — microbiology — Posted on 2021-03-15

2600 Host F-box protein 22 enhances the uptake of Brucella by macrophages and drives a sustained release of pro-inflammatory cytokines through degradation of the anti-inflammatory effector proteins of Brucella.

Radhakrishnan, G.; Mazumdar, V.; Joshi, K.; Nandi, B. R.; Namani, S.; Gupta, V. K.

10.1101/2021.03.15.435452 — microbiology — Posted on 2021-03-15

2601 Hillslope geodiversity shapes ammonia-oxidizing communities and other microbial regulators in a semi-arid shrubland

Szitenberg, A.; Alexander-Shani, R.; Yizhak, H.; Stavi, I.

10.1101/2021.03.08.434393 — microbiology — Posted on 2021-03-16

2602 BNT162b2 mRNA COVID-19 vaccine induces antibodies of broader cross-reactivity than natural infection but recognition of mutant viruses is up to 10-fold reduced

Mohsen, M.; Bachmann, M. F.; Vogel, M.; Augusto, G. S.; Liu, X.; Chang, X.

10.1101/2021.03.13.435222 — immunology — Posted on 2021-03-15

2603 Dynamic cortico-cortical information transfer regimes during vocalization

García-Rosales, F.; Lopez-Jury, L.; Gonzalez-Palomares, E.; Wetekam, J.; Cabral-Calderin, Y.; Kiai, A.; Kössl, M.; Hechavarria, J. C.

10.1101/2021.03.15.435430 — neuroscience — Posted on 2021-03-15

2604 Anatomical and Functional Gradients Shape Dynamic Functional Connectivity in the Human Brain

Kong, X.; Kong, R.; Orban, C.; Wang, P.; zhang, s.; Anderson, K. M.; Holmes, A.; Murray, J. D.; Deco, G.; van den heuvel, m.; Yeo, B. T. T.

10.1101/2021.03.15.435361 — neuroscience — Posted on 2021-03-15

2605 Amplitude and phase coupling optimize information transfer between brain networks that function at criticality

Avramiea, A.-E.; Masood, A.; Mansvelder, H. D.; Linkenkaer-Hansen, K.

10.1101/2021.03.15.435461 — neuroscience — Posted on 2021-03-15

2606 Structure Can Predict Function in the Human Brain: A Graph Neural Network Deep Learning Model of Functional Connectivity and Centrality based on Structural Connectivity

Neudorf, J.; Kress, S.; Borowsky, R.

10.1101/2021.03.15.435531 — neuroscience — Posted on 2021-03-15

2607 Gel-like inclusions of C-terminal fragments of TDP-43 sequester and inhibit proteasomes in neurons

Riemenschneider, H.; Guo, Q.; Bader, J.; Frottin, F.; Farny, D.; Kleinberger, G.; Haass, C.; Mann, M.; Hartl, F. U.; Baumeister, W.; Hipp, M. S.; Meissner, F.; Fernandez-Busnadiego, R.; Edbauer, D.

10.1101/2021.03.15.435268 — neuroscience — Posted on 2021-03-16

2608 Structural Covariance Networks in Post-Traumatic Stress Disorder: A Multisite ENIGMA-PGC Study

Rakesh, G.; Sun, D.; Logue, M.; Clarke-Rubright, E.; O Leary, B. M.; Haswell, C.; Xie, H.; Thompson, P.; Dennis, E.; Jahanshad, N.; Koch, S.; Frijling, J.; Nawijn, L.; Olff, M.; van Zuiden, M.; Rashid, F.; Zhu, X.; De Bellis, M.; Daniels, J. K.; Sierk, A.; Manthey, A.; Stevens, J. S.; Jovanovic, T.; Stein, M. B.; Shenton, M.; van der Werff, S. J. A.; van der Wee, N. J. A.; Vermeiren, R. R. J. M.; Schmahl, C.; Herzog, J.; Kaufman, M. L.; O'Connor, L.; Lebois, L. A. M.; Baker, J. T.; Gruber, S. A.; Wolff, J. D.; Wolf, E. J.; Winternitz, S.; Gonenc, A.; Ressler, K. J.; Hofmann, D.; Bryant, R. A.;

10.1101/2021.03.13.432212 — neuroscience — Posted on 2021-03-16

2609 Flow cytometry allows rapid detection of protein aggregates in cell culture and zebrafish models of spinocerebellar ataxia-3

Robinson, K. J.; Tym, M. C.; Hogan, A.; Watchon, M.; Yuan, K. C.; Plenderleith, S. K.; Don, E. K.; Laird, A. S.

10.1101/2021.03.09.434364 — neuroscience — Posted on 2021-03-16

2610 The human visual system preserves the hierarchy of 2-dimensional pattern regularity

Kohler, P. J.; Clarke, A. D. F.

10.1101/2021.02.05.429884 — neuroscience — Posted on 2021-03-16

2611 A single amino acid polymorphism in a conserved effector of the multihost blast fungus pathogen expands host-target binding spectrum

Bentham, A. R.; Petit-Houdenot, Y.; Win, J.; Chuma, I.; Terauchi, R.; Banfield, M. J.; Kamoun, S.; Langner, T.

10.1101/2021.03.15.435478 — plant biology — Posted on 2021-03-16

2612 First isolation of virulent Tenacibaculum maritimum strains from diseased orbicular batfish (Platax orbicularis) farmed in Tahiti Island

Lopez, P.; Saulnier, D.; Swarup-Gaucher, S.; David, R.; Lau, C.; Taputuarai, R.; Belliard, C.; Basset, C.; Labrune, V.; Marie, A.; Bernardet, J. F.; Duchaud, E.

10.1101/2021.03.15.435441 — pathology — Posted on 2021-03-15

2613 Gα13 loss promotes tumor progression in the KPC transgenic mouse model of advanced pancreatic cancer

Shields, M. A.; Spaulding, C.; Khalafalla, M. G.; Pham, T. N.; Munshi, H. G.

10.1101/2021.03.15.435488 — cancer biology — Posted on 2021-03-15

2614 Using fecal immunochemical tubes for the analysis of gut microbiome has potential to improve colorectal cancer screening

Krigul, K. L.; Aasmets, O.; Lull, K.; Org, T.; Org, E.

10.1101/2021.03.15.435399 — cancer biology — Posted on 2021-03-15

2615 A minimal robophysical model of quadriflagellate self-propulsion

Diaz, K.; Robinson, T. L.; Ozkan Aydin, Y.; Aydin, E.; Goldman, D. I.; Wan, K. Y.

10.1101/2021.03.14.434582 — biophysics — Posted on 2021-03-15

2616 Automated Modeling of Protein Accumulation at DNA Damage Sites using qFADD.py

Bowerman, S.; Mahadevan, J.; Benson, P.; Rudolph, J.; Luger, K.

10.1101/2021.03.15.435501 — biophysics — Posted on 2021-03-15

2617 Effects of Mutations in the Receptor-Binding Domain of SARS-CoV-2 Spike on its Binding Affinity to ACE2 and Neutralizing Antibodies Revealed by Computational Analysis

Bozdaganyan, M. E.; Sokolova, O. S.; Shaitan, K. V.; Kirpichnikov, M. P.; Orekhov, P. S.

10.1101/2021.03.14.435322 — biophysics — Posted on 2021-03-15

2618 Modeling the three-way feedback between cellular contractility, actin polymerization, and adhesion turnover resolves the contradictory effects of RhoA and Rac1 on endothelial junction dynamics

McEvoy, E.; Sneh, T.; Moeendarbary, E.; Marino, G. E.; Chen, X.; Escribano, J.; Spill, F.; Garcia-Aznar, J. M.; Weeraratna, A. T.; Svitkina, T. M.; Kamm, R. D.; Shenoy, V. B.

10.1101/2021.03.15.435512 — biophysics — Posted on 2021-03-16

2619 DNA tension-modulated translocation and loop extrusion by SMC complexes revealed by molecular dynamics simulations

Nomidis, S. S.; Carlon, E.; Gruber, S.; Marko, J. F.

10.1101/2021.03.15.435506 — biophysics — Posted on 2021-03-16

2620 Combined fluorescence, optical diffraction tomography and Brillouin microscopy

Schlüssler, R.; Kim, K.; Nötzel, M.; Taubenberger, A. V.; Abuhattum, S.; Beck, T.; Müller, P.; Maharana, S.; Cojoc, G.; Girardo, S.; Hermann, A.; Alberti, S.; Guck, J.

10.1101/2020.10.30.361808 — biophysics — Posted on 2021-03-16

2621 GTP and lipids control self-assembly and functional promiscuity of Dynamin2 molecular machinery

Espadas, J.; Membrane Nanomechanics, ; Bocanegra, R.; Machanisms of Cellular Membrane Remodelling, ; Martinez-Galvez, J. M.; Molecular Motors Manipulation Lab, ; Largo, E.; Banos-Mateos, S.; Arrasate, P.; Ormaetxea-Guisasola, J.; Velasco-Olmo, A.; Vera Lillo, J.; Ibarra, B.; Shnyrova, A. V.; Frolov, V. A.

10.1101/2021.03.15.435402 — biophysics — Posted on 2021-03-16

2622 Microbial diversity in raw milk and Sayram Ketteki from southern of Xinjiang, China

Gao, D.; Wang, W.; Han, Z.; Xi, Q.; Guo, R.; kuang, P.; Li, D.

10.1101/2021.03.15.435442 — bioinformatics — Posted on 2021-03-15

2623 Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops.

Urrutia, I.; Ault, J.; Sobott, F.; Savery, N.; Dillingham, M. S.

10.1101/2021.03.15.435481 — biochemistry — Posted on 2021-03-15

2624 One-shot identification of SARS-CoV-2 S RBD escape mutants using yeast screening

Francino Urdaniz, I.; Steiner, P. J.; Kirby, M.; Zhao, F.; Haas, C. M.; Barman, S.; Rhodes, E. R.; Peng, L.; Sprenger, K.; Jardine, J.; Whitehead, T. A.

10.1101/2021.03.15.435309 — biochemistry — Posted on 2021-03-15

2625 Hydroxycarboxylic acid receptor 2 (HCAR2/GPR109A) expression and signaling promotes the maintenance of an immunoinhibitory retinal environment

Powell, F.; Tawfik, A.; Arjunan, P.; Chopra, D. G.; Al-Shabrawey, M.; Singh, N.; Jadeja, R. N.; Kaufman, M.; Jones, M.; Fromal, O.; Saul, A.; Jahng, W. J.; Bartoli, M.; Martin, P. M.

10.1101/2021.03.15.435493 — biochemistry — Posted on 2021-03-15

2626 Preparation of E. coli RNA polymerase transcription elongation complexes for systematic RNA assays

Strobel, E. J.

10.1101/2021.03.15.435517 — biochemistry — Posted on 2021-03-15

2627 A structure-derived mechanism reveals how capping protein promotes nucleation in branched actin networks

Funk, J.; Merino, F.; Schaks, M.; Rottner, K.; Raunser, S.; Bieling, P.

10.1101/2021.03.15.435411 — biochemistry — Posted on 2021-03-15

2628 Development of novel MOG analogues with increased stability to explore MCT2 and α-ketoglutarate biology in vivo

Fets, L.; Nunes, P. M.; Campos, S.; Silva dos Santos, M.; Bevan, N.; Sherriff, E. B.; MacRae, J. I.; House, D.; Anastasiou, D.

10.1101/2021.03.15.433711 — biochemistry — Posted on 2021-03-15

2629 Structural basis for late maturation steps of the human mitoribosomal large subunit

Rorbach, J.; Cipullo, M.; Valentin Gese, G.; Hallberg, M.; Khawaja, A.

10.1101/2021.03.15.435084 — biochemistry — Posted on 2021-03-15

2630 The Hsp90 chaperone system from the African trypanosome, Trypanosoma brucei

Boshoff, A.; Jamabo, M.; Bentley, S. J.; Macucule-Tinga, P.; Edkins, A.

10.1101/2021.03.15.435448 — biochemistry — Posted on 2021-03-15

2631 Structural insights into the role of Dicer-related helicase 3 in RNAi in Caenorhabditis elegans.

Li, K.; Zheng, J.; Wirawan, M.; Nguyen, T. M.; Fedorova, O.; Griffin, P.; Pyle, A. M.; Luo, D.

10.1101/2021.03.14.433363 — biochemistry — Posted on 2021-03-16

2632 Recurrent structural variations of lncRNA gene CCDC26 in diffuse intrinsic pontine glioma

Zou, L.

10.1101/2021.03.14.435351 — genomics — Posted on 2021-03-15

2633 Complex genetic architecture of three-dimensional craniofacial shape variation in domestic pigeons

Boer, E. F.; Maclary, E. T.; Shapiro, M. D.

10.1101/2021.03.15.435516 — genetics — Posted on 2021-03-15

2634 A ROR2 coding variant is associated with craniofacial variation in domestic pigeons

Boer, E. F.; Van Hollebeke, H. F.; Holt, C.; Yandell, M.; Shapiro, M. D.

10.1101/2021.03.15.435542 — genetics — Posted on 2021-03-15

2635 A signature of Neanderthal introgression on molecular mechanisms of environmental responses

Findley, A.; Zhang, X.; Boye, C.; Lin, Y.-L.; Kalita, C.; Barreiro, L.; Lohmueller, K. E.; Pique-Regi, R.; Luca, F.

10.1101/2021.03.15.435179 — evolutionary biology — Posted on 2021-03-15

2636 Complex population dynamics in a spatial microbial ecosystem with Physarum polycephalum

Epstein, L.; Dubois, Z.; Smith, J.; Lee, Y.; Harrington, K. I.

10.1101/2021.03.14.435300 — ecology — Posted on 2021-03-15

2637 Seasonal occurrence of Japanese pygmy octopus Octopus parvus in the intertidal zone

Yamate, Y.; Ohya, T.; Wada, T.; Takegaki, T.

10.1101/2021.03.14.435358 — ecology — Posted on 2021-03-15

2638 Phylogeography and Proline amino acid usage of Asian tiger mosquito Aedes albopictus (Skuse 1894) populations along landscape gradients in Indonesia

Wibowo, A. A.

10.1101/2021.03.14.435316 — ecology — Posted on 2021-03-15

2639 Infective prey leads to a partial role reversal in a predator-prey interaction

Kaitala, V.; Koivu-Jolma, M.; Laakso, J.

10.1101/2021.03.15.435444 — ecology — Posted on 2021-03-15

2640 Twenty years of change in benthic communities across the Belizean Barrier Reef

Bruno, J. F.; Alves, C.; Aronson, R. B.; Bood, N.; Castillo, K. D.; Cox, C.; Fieseler, C.; Locklear, Z.; McField, M.; Mudge, L.; Umbanhowar, J.; Valdivia, A.

10.1101/2021.03.15.435443 — ecology — Posted on 2021-03-15

2641 Clumpy coexistence in phytoplankton: The role of functional similarity in community assembly

Graco-Roza, C.; Segura, A. M.; Kruk, C.; Domingos, P.; Soininen, J.; Marinho, M. M.

10.1101/869966 — ecology — Posted on 2021-03-16

2642 Morphometry of newborn piglets and its relevance at weaning

Silva, L. M.; Fidelis, P. H. S.; Gomes, L. V. L.; Santos, G. A.; Oliveira, A. M. A.; Medeiros, E. S.; Araujo, M. S.; Moreira, R. H. R.

10.1101/2021.03.15.435415 — developmental biology — Posted on 2021-03-15

2643 Chromosome counting in the mouse and human zygote using low-invasive super-resolution live-cell imaging

Hatano, Y.; Mashiko, D.; Tokoro, M.; Yao, T.; Hirao, R.; Kitasaka, H.; Fukunaga, N.; Asada, Y.; Yamagata, K.

10.1101/2021.03.14.435348 — developmental biology — Posted on 2021-03-15

2644 S-acylation controls SARS-Cov-2 membrane lipid organization and enhances infectivity

Mesquita, F. S.; Abrami, L.; Sergeeva, O.; Turelli, P.; Kunz, B.; Raclot, C.; Paz Montoya, J.; Abriata, L.; Dal Peraro, M.; Trono, D.; D'Angelo, G.; van der Goot, F. G.

10.1101/2021.03.14.435299 — cell biology — Posted on 2021-03-15

2645 Diversification of Transcription Factor NF-κB in Protists

Williams, L. M.; Sridhar, S.; Samaroo, J.; Adindu, E. K.; Addanki, A.; BB522 Molecular Biology Laboratory, ; Aguirre Carrion, P. J.; DiRusso, C. J.; Rodriguez-Sastre, N.; Siggers, T.; Gilmore, T. D.

10.1101/2021.03.15.435342 — cell biology — Posted on 2021-03-15

2646 Effect of nandrolone decanoate on healing of experimentally induced radial nonunion in rabbits (Oryctolagus cuniculus)

Dissenha, A.; Minto, B.; Calciolari, K.; Sargi, L. F.; Do Nascimento, L. C.; Rocha, F. D. L.; Galindez, J. A. S.; De Lucena, D. V. F.; Dias, L. G. G. G.

10.1101/2021.03.15.435445 — cell biology — Posted on 2021-03-15

2647 Purine auxotrophic starvation evokes quiescence like phenotype in the budding yeast

Kokina, A.; Ozolina, Z.; Pleiko, K.; Svirksts, K.; Tanilas, K.; Vamza, I.; Liepins, J.

10.1101/2021.03.15.435510 — cell biology — Posted on 2021-03-15

2648 Regression QSAR Models for Predicting HIV-1 Integrase Inhibitors

Ha, C. H. X.; Lee, N. K.; Rahman, T.; Hwang, S. S.; Yam, W. K.; Chee, X. W.

10.1101/2021.02.23.432583 — pharmacology and toxicology — Posted on 2021-03-16

2649 Inactivation of Aβ42 Protomer-protomer Dissociation Reaction by Pentamer Dimer Formation

Kurisaki, I.; Tanaka, S.

10.1101/2021.02.12.431048 — biophysics — Posted on 2021-03-16

2650 Insights into Mus musculus subspecies population structure across Eurasia revealed by whole-genome sequence analysis

Fujiwara, K.; Kawai, Y.; Moriwaki, K.; Takada, T.; Shiroishi, T.; Saitou, N.; Suzuki, H.; Osada, N.

10.1101/2021.02.05.429881 — genomics — Posted on 2021-03-16

2651 Systematic benchmarking of tools for CpG methylation detection from Nanopore sequencing

Yuen, Z. W.-S.; Srivastava, A.; Daniel, R.; McNevin, D.; Jack, C.; Eyras, E.

10.1101/2020.10.14.340315 — bioinformatics — Posted on 2021-03-15

2652 Common postzygotic mutational signature in multiple healthy adult tissues related to embryonic hypoxia

Hong, Y.; Zhang, D.; Zhou, X.; Chen, A.; Abliz, A.; Bai, J.; Wang, L.; Hu, Q.; Gong, K.; Guan, X.; Liu, M.; Zheng, X.; Lai, S.; Qu, H.; Zhao, F.; Hao, S.; Wu, Z.; Cai, H.; Hu, S.; Ma, Y.; Zhang, J.; Ke, Y.; Wang, Q.; Chen, W.; Zeng, C.

10.1101/2020.02.17.952473 — genetics — Posted on 2021-03-15

2653 Visual Cortical Area MT is Required For Development of the Dorsal Stream and Associated Visuomotor Behaviours

Kwan, W. C.; Chang, C.-K.; Yu, H.-H.; Mundinano, I.-C. C.; Fox, D. M.; Homman-Ludiye, J.; Bourne, J.

10.1101/2021.02.28.433301 — neuroscience — Posted on 2021-03-15

2654 Neural evidence for narrative-based processing of evidence and bias in juror decision making

Castrellon, J. J.; Hakimi, S.; Parelman, J. M.; Yin, L.; Law, J. R.; Skene, J. A. G.; Ball, D. A.; Malekpour, A.; Beskind, D. H.; Vidmar, N.; Pearson, J. M.; Skene, J. H. P.; Carter, R. M.

10.1101/2020.11.11.378935 — neuroscience — Posted on 2021-03-15

2655 Bridges, not walls: the hippocampus builds narrative memories across distant events

Cohn-Sheehy, B. I.; Delarazan, A. I.; Reagh, Z. M.; Crivelli-Decker, J. E.; Kim, K.; Barnett, A. J.; Zacks, J. M.; Ranganath, C.

10.1101/2020.12.11.422162 — neuroscience — Posted on 2021-03-15

2656 The openCARP Simulation Environment for Cardiac Electrophysiology

Plank, G.; Loewe, A.; Neic, A.; Augustin, C.; Huang, Y.-L.; Gsell, M. A. F.; Karabelas, E.; Nothstein, M.; Sanchez, J.; Prassl, A. J.; Seemann, G.; Vigmond, E. J.

10.1101/2021.03.01.433036 — bioinformatics — Posted on 2021-03-15

2657 Mechanistic within-host models of the asexual Plasmodium falciparum infection: a review and analytical assessment

Camponovo, F.; Lee, T. E.; Russell, J.; Burgert, L.; Gerardin, J.; Penny, M. A.

10.1101/2021.03.05.434041 — bioinformatics — Posted on 2021-03-15

2658 Mosquito Larvae (Culex spp.) Startle Responses to Vibration Stimuli

Harrison, E. R.; Budenberg, W. J.

10.1101/2021.02.18.431787 — animal behavior and cognition — Posted on 2021-03-15

2659 BMP signaling is necessary and sufficient for osteoarthritis and a target for disease modifying therapy

Jaswal, A. P.; Roelofs, A. J.; Singh, A. K.; Kumar, B.; Riemen, A. H. K.; Wang, H.; Sadaf, A.; Nanasaheb, S. V.; Iqbal, S. F.; Agnihotri, N.; De Bari, C.; Bandyopadhyay, A.

10.1101/2021.03.01.433366 — developmental biology — Posted on 2021-03-15

2660 Modulation of fatty acid elongation sustains sexually dimorphic hydrocarbons and female attractiveness in Blattella germanica (L.)

Pei, X.-J.; Fan, Y.-L.; Bai, Y.; Bai, T.-T.; Schal, C.; Zhang, Z.-F.; Chen, N.; Li, S.; Liu, T.-X.

10.1101/2021.03.04.434003 — molecular biology — Posted on 2021-03-15

2661 A Scalable Screening of E. coli Strains for Recombinant Protein Expression

Morao, L. G.; Manzine, L. R.; Barra, A. L. C.; Clementino, L. O. D.; Gutierrez, R. F.; Wrenger, C.; Nascimento, A. S.

10.1101/2021.03.09.434560 — molecular biology — Posted on 2021-03-15

2662 Restructured mitochondrial-nuclear interaction in Plasmodium falciparum dormancy and persister survival after artemisinin exposure

Connelly, S. V.; Manzella-Lapeira, J.; Levine, Z. C.; Brzostowski, J.; Krymskaya, L.; Rahman, R. S.; Ellis, A. C.; Amin, S. N.; Sa, J. M.; Wellems, T. E.

10.1101/2020.09.28.314435 — microbiology — Posted on 2021-03-15

2663 Gene flux and acid-imposed selection are the main drivers of antimicrobial resistance in broiler chicks infected with Salmonella enterica serovar Heidelberg

Oladeinde, A.; Abdo, Z.; Press, M. O.; Cook, K.; Cox, N. A.; Zwirzitz, B.; Woyda, R.; Lakin, S. M.; Thomas, J. C.; Looft, T.; Cosby, D. E.; Hinton, A.; Guard, J.; Line, E.; Rothrock, M. J.; Berrang, M. E.; Herrington, K.; Zock, G.; Plumblee Lawrence, J.; Cudnik, D.; House, S.; Ingram, K.; Lariscy, L.; Wagner, M.; Aggrey, S. E.; Chai, L.; Ritz, C.

10.1101/2021.02.25.432983 — microbiology — Posted on 2021-03-15

2664 Bruton's Tyrosine Kinase Supports Gut Mucosal Immunity and Commensal Microbiome Recognition in Autoimmune Arthritis

Bonami, R. H.; Thurman, C. E.; Nyhoff, L. E.; Westlake, C. S.; Barron, B. B.; Kendall, P. L.

10.1101/2021.03.10.434762 — immunology — Posted on 2021-03-15

2665 Hippocampal and thalamic afferents form distinct synaptic microcircuits in the mouse frontal cortex

Graham, K.; Spruston, N.; Bloss, E. B.

10.1101/2021.03.12.435140 — neuroscience — Posted on 2021-03-15

2666 Stimulated oxygen transport in tissue by magnetic needle acupuncture

Liu, Z.; Wen, C.; Zhang, S.

10.1101/2021.02.01.426016 — physiology — Posted on 2021-03-15

2667 Sharpened and mechanically durable carbon fiber electrode arrays for neural interfacing

Welle, E. J.; Woods, J. E.; Jiman, A. A.; Richie, J. M.; Bottorff, E. C.; Ouyang, Z.; Seymour, J. P.; Patel, P. R.; Bruns, T. M.; Chestek, C. A.

10.1101/2021.01.21.427697 — bioengineering — Posted on 2021-03-15

2668 LEA motifs promote desiccation tolerance in vivo

Hibshman, J. D.; Goldstein, B.

10.1101/2021.02.04.429810 — genetics — Posted on 2021-03-15

2669 Locally-adaptive inversions modulate genetic variation at different geographic scales in a seaweed fly

Merot, C.; Berdan, E.; Cayuela, H.; Djambazian, H.; Ferchaud, A.-L.; Laporte, M.; Normandeau, E.; Ragoussis, J.; Wellenreuther, M.; Bernatchez, L.

10.1101/2020.12.28.424584 — evolutionary biology — Posted on 2021-03-15

2670 Relative time constraints improve molecular dating

Szollosi, G. J.; Hoehna, S.; Williams, T. A.; Schrempf, D.; Daubin, V.; Boussau, B.

10.1101/2020.10.17.343889 — evolutionary biology — Posted on 2021-03-15

2671 Adaptive evolution of Moniliophthora PR-1 proteins towards its pathogenic lifestyle

Vasconcelos, A. A.; Jose, J.; Tokimatu Filho, P. M.; Camargo, A. P.; Teixeira, P. J. P. L.; Thomazella, D. P. T.; Prado, P. F. V.; Fiorin, G. L.; Costa, J. L.; Figueira, A.; Carazzolle, M. F.; Pereira, G. A. G.; Baroni, R. M.

10.1101/2021.03.07.434232 — evolutionary biology — Posted on 2021-03-15

2672 Evolution of diversity in metabolic strategies

Caetano, R. A.; Ispolatov, Y.; Doebeli, M.

10.1101/2020.10.20.347419 — evolutionary biology — Posted on 2021-03-15

2673 Intergenerational niche differentiation in filmy ferns (Hymenophyllaceae)

Nitta, J. H.; Watkins, J. E.; Holbrook, N. M.; Wang, T.; Davis, C. C.

10.1101/2021.03.12.435213 — ecology — Posted on 2021-03-15

2674 Scaling of subcellular structures with cell length through decelerated growth

McInally, S. G.; Kondev, J.; Goode, B. L.

10.1101/2021.03.01.433461 — cell biology — Posted on 2021-03-15

2675 Healthy Choice depends on the latency and rate of information accumulation

Sullivan, N. J.; Huettel, S. A.

10.1101/465393 — neuroscience — Posted on 2021-03-15

2676 Cortical network underlying speech production during delayed auditory feedback

Ozker Sertel, M.; Doyle, W.; Devinsky, O.; Flinker, A.

10.1101/2020.11.11.378471 — neuroscience — Posted on 2021-03-15

2677 Macrophages orchestrate the expansion of a pro-angiogenic perivascular niche during cancer progression

Opzoomer, J. W.; Anstee, J. E.; Dean, I.; Hill, E. J.; Bouybayoune, I.; Caron, J.; Muliaditan, T.; Gordon, P.; Sosnowska, D.; Nuamah, R.; Pinder, S. E.; Ng, T.; Dazzi, F.; Kordasti, S.; Withers, D. R.; Lawrence, T.; Arnold, J. N.

10.1101/2020.10.30.361907 — cancer biology — Posted on 2021-03-15

2678 Characterization of immunoactive and immunotolerant CD4+ T cells in breast cancer by measuring activity of signaling pathways that determine immune cell function

Wesseling-Rozendaal, Y.; van Doorn, A.; Willard-Gallo, K.; van de Stolpe, A.

10.1101/2020.10.08.292557 — cancer biology — Posted on 2021-03-15

2679 Dimerization of a membrane transporter is driven by differential energetics of lipid solvation of dissociated and associated states

Chadda, R.; Bernhardt, N.; Kelley, E. G.; Teixeira, S. C. M.; Griffith, K.; Gil-Ley, A.; Ozturk, T. N.; Hughes, L. E.; Forsythe, A.; Krishnamani, V.; Faraldo-Gomez, J.; Robertson, J. L.

10.1101/2020.10.05.327239 — biophysics — Posted on 2021-03-15

2680 High-throughput tandem-microwell assay for ammonia repositions FDA-Approved drugs to Helicobacter pylori infection

Liu, F.; Yu, J.; Zhang, Y.; Li, F.; Liu, Q.; Zhou, Y.; Huang, S.; Fang, H.; Xiao, Z.; Liao, L.; Xu, J.; Wu, X.-Y.; Wu, F.

10.1101/2021.01.05.425432 — biochemistry — Posted on 2021-03-15

2681 The stability landscape of de novo TIM barrels explored by a modular design approach

Romero-Romero, S.; Costas, M.; Silva, D.-A.; Kordes, S.; Rojas-Ortega, E.; Guerra, Y.; Tapia, C.; Shanmugaratnam, S.; Rodriguez-Romero, A.; Baker, D.; Höcker, B.; Fernandez-Velasco, D. A.

10.1101/2020.09.29.319103 — biochemistry — Posted on 2021-03-15

2682 Multi-scale systems genomics analysis predicts pathways, cell types and drug targets involved in normative human cognition variation

Pai, S.; Hui, S.; Weber, P.; Narayan, S.; Whitley, O.; LI, P.; Labrie, V.; Baumbach, J.; Bader, G. D.

10.1101/751933 — genomics — Posted on 2021-03-15

2683 High-throughput transcriptomic evaluation of per- and polyfluoroalkyl substances (PFAS) in primary human liver spheroids to inform read-across

Rowan-Carroll, A.; Readon, A.; Leingartner, K.; Gagne, R.; Williams, A.; Meier, M. J.; Kuo, B.; Bourdon-lacombe, J.; Moffat, I.; Carrier, R.; Nong, A.; lorusso, l.; Ferguson, S. S.; Atlas, E.; Yauk, C.

10.1101/2020.10.15.341362 — genomics — Posted on 2021-03-15

2684 Ancestry Inference Using Reference Labeled Clusters of Haplotypes

Wang, Y.; Song, S.; Schraiber, J. G.; Sedghifar, A.; Byrnes, J. K.; Turissini, D. A.; Hong, E. L.; Ball, C. A.; Noto, K.

10.1101/2020.09.23.310698 — genomics — Posted on 2021-03-15

2685 Ancient viral genomes reveal introduction of HBV and B19V into Mexico during the transatlantic slave trade.

Guzman-Solis, A. A.; Blanco-Melo, D.; Villa-Islas, V.; Bravo-Lopez, M. J.; Sandoval-Velasco, M.; Wesp, J. K.; Gomez-Valdes, J. A.; Moreno-Cabrera, M. d. l. L.; Meraz-Moreno, A.; Solis-Pichardo, G.; Schaaf, P.; tenOever, B. R.; Avila-Arcos, M. C.

10.1101/2020.06.05.137083 — genomics — Posted on 2021-03-15

2686 On Rank Deficiency in Phenotypic Covariance

OKeefe, F. R.

10.1101/2020.07.23.218289 — evolutionary biology — Posted on 2021-03-15

2687 Complex community-wide consequences of consumer sexual dimorphism

De Lisle, S.; Schreiber, S.; Bolnick, D. I.

10.1101/634782 — ecology — Posted on 2021-03-15

2688 Global analysis of cell behavior and protein localization dynamics reveals region-specific functions for Shroom3 and N-cadherin during neural tube closure.

Baldwin, A.; Kim, J.; Wallingford, J. B.

10.1101/2021.01.19.427312 — developmental biology — Posted on 2021-03-15

2689 Sleep spindles preferentially consolidate weakly encoded memories

Denis, D.; Mylonas, D.; Poskanzer, C.; Bursal, V.; Payne, J. D.; Stickgold, R.

10.1101/2020.04.03.022434 — neuroscience — Posted on 2021-03-15

2690 No evidence of Toxoplasma Gondii infection in urban and rural squirrels

Kinnunen, R. P.; Schmidt, C.; Hernandez-Ortiz, A.; Garroway, C. J.

10.1101/2020.09.28.313866 — pathology — Posted on 2021-03-15

2691 A minimal hepatocyte growth factor mimic acting as a powerful agonist of the MET receptor tyrosine kinase for regeneration of epithelial tissues and organs.

Leclerc, B.; de Nola, G.; Mougel, A.; Dezitter-Taront, S.; Simonneau, C.; Forneris, F.; Adriaenssens, E.; Drobecq, H.; Gherardi, E.; Melnyk, O.; de Jonge, H.; Vicogne, J.

10.1101/2020.07.20.212654 — bioengineering — Posted on 2021-03-15

2692 Structure, Mechanism and Crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase

Newman, J. A.; Douangamath, A.; Yazdani, S.; Yosaatmadja, Y.; Aimon, A.; Brandao-Neto, J.; Dunnett, L.; Gorrie-Stone, T.; Skyner, R.; Fearon, D.; Schapira, M.; von Delft, F.; Gileadi, O.

10.1101/2021.03.15.435326 — biochemistry — Posted on 2021-03-15

2693 Differential gene expression by RNA-Seq in Sigma-2 Receptor/TMEM97 knockout cells reveals its role in complement activation and SARS-CoV-2 viral uptake

Riad, A.; Aubert, Y.; Zeng, C.; Graham, T. J. A.; Petersson, E. J.; Capell, B. C.; Mach, R. H.

10.1101/2021.03.14.435180 — cell biology — Posted on 2021-03-15

2694 A map of direct SARS-CoV-2 protein interactions implicates specific human host processes

10.1101/2021.03.15.433877 — systems biology — Posted on 2021-03-15

2695 Cetylpyridinium chloride-containing mouthwashes reduce the infectivity of SARS-CoV-2 variants in vitro

Munoz-Basagoiti, J.; Perez-Zsolt, D.; Leon, R.; Blanc, V.; Raich-Regue, D.; Cano-Sarabia, M.; Trinite, B.; Pradenas, E.; Blanco, J.; Gispert, J.; Clotet, B.; Izquierdo-Useros, N.

10.1101/2020.12.21.423779 — microbiology — Posted on 2021-03-15

Jauregi, A.; Wang, H.; Hassel, S.; Kessler, K.

10.1101/2021.03.14.435306 — neuroscience — Posted on 2021-03-15

2697 Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV

Stukalov, A.; Girault, V.; Grass, V.; Karayel, O.; Bergant, V.; Urban, C.; Haas, D. A.; Huang, Y.; Oubraham, L.; Wang, A.; Hamad, S. M.; Piras, A.; Hansen, F. M.; Tanzer, M.; Paron, I.; Zinzula, L.; Engleitner, T.; Reinecke, M.; Lavacca, T. M.; Ehmann, R.; Wölfel, R.; Jores, J.; Küster, B.; Protzer, U.; Rad, R.; Ziebuhr, J.; Thiel, V.; Scaturro, P.; Mann, M.; Pichlmair, A.

10.1101/2020.06.17.156455 — systems biology — Posted on 2021-03-15

2698 BEdeepoff: an in silico tool for off-target prediction of ABE and CBE base editors

Zhang, C.; Wang, D.; Qi, T.; Zhang, Y.; Hou, L.; Lan, F.; Yang, J.; Ong, S.-G.; Wang, H.; Shi, L.; Wang, Y.

10.1101/2021.03.14.435296 — bioinformatics — Posted on 2021-03-15

2699 BEdeepon: an in silico tool for prediction of base editor efficiencies and outcomes

Zhang, C.; Wang, D.; Qi, T.; Zhang, Y.; Hou, L.; Lan, F.; Yang, J.; Shi, L.; Ong, S.-G.; Wang, H.; Wang, Y.

10.1101/2021.03.14.435303 — bioinformatics — Posted on 2021-03-15

2700 Paired SARS-CoV-2 Spike Protein Mutations Observed During Ongoing SARS-CoV-2 Viral Transfer from Humans to Minks and Back to Humans

Rubsamen, R.; Burkholz, S.; Pokhrel, S.; Kraemer, B. R.; Mochly-Rosen, D.; Carback, R. T.; Hodge, T.; Harris, P.; Ciotlos, S.; Wang, L.; Herst, C.

10.1101/2020.12.22.424003 — genetics — Posted on 2021-03-15

2701 A free-living protist that lacks canonical eukaryotic DNA replication and segregation systems

Salas-Leiva, D. E. E.; Tromer, E. C.; Curtis, B. A.; Jerlstrom-Hultqvist, J.; Kolisko, M.; Yi, Z.; Salas-Leiva, J. S.; Gallot-Lavallee, L.; Kops, G. J. P. L.; Archibald, J. M.; Simpson, A. G. B.; Roger, A. J.

10.1101/2021.03.14.435266 — evolutionary biology — Posted on 2021-03-15

2702 Design of bacterially expressed influenza stem immunogens displayed on Msdps2 protein nanoparticles

Kar, U.; Garg, P.; Khaleeq, S.; Vignesh, V. S.; Upadhyaya, A.; Das, M.; Pandey, S.; Dutta, S.; Varadarajan, R.

10.1101/2021.03.14.435294 — immunology — Posted on 2021-03-15

2703 A General LSTM-based Deep Learning Method for Estimating Neuronal Models and Inferring Neural Circuitry

Sheng, K.; Qu, P.; Yang, L.; Liu, X.; He, L.; Ma, L.; Du, K.

10.1101/2021.03.14.434027 — neuroscience — Posted on 2021-03-15

2704 A Synthesis of the Many Errors and Learning Processes of Visuomotor Adaptation

Morehead, J. R.; Orban de Xivry, J.-J.

10.1101/2021.03.14.435278 — neuroscience — Posted on 2021-03-15

2705 A novel soluble ACE2 protein totally protects from lethal disease caused by SARS-CoV-2 infection

Hassler, L.; Wysocki, J.; Gelarden, I.; Tomatsidou, A.; Gula, H.; Nicoleascu, V.; Randall, G.; Henkin, J.; Yeldandi, A.; Batlle, D.

10.1101/2021.03.12.435191 — pathology — Posted on 2021-03-15

2706 Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of virus isolates

Schroers, B.; Gudimella, R.; Bukur, T.; Roesler, T.; Loewer, M.; Sahin, U.

10.1101/2021.02.04.429765 — genomics — Posted on 2021-03-15

2707 ChAdOx1 nCoV-19 (AZD1222) protects hamsters against SARS-CoV-2 B.1.351 and B.1.1.7 1 disease

Fischer, R.; van Doremalen, N.; Adney, D.; Yinda, C.; Port, J.; Holbrook, M.; Schulz, J.; Williamson, B.; Thomas, T.; Barbian, K.; Anzick, S.; Ricklefs, S.; Smith, B.; Long, D.; Martens, C.; Saturday, G.; de Wit, E.; Gilbert, S.; Lambe, T.; Munster, V.

10.1101/2021.03.11.435000 — microbiology — Posted on 2021-03-15

2708 Effect of natural mutations of SARS-CoV-2 on spike structure, conformation and antigenicity

Gobeil, S.; Janowska, K.; McDowell, S.; Mansouri, K.; Parks, R.; Stalls, V.; Kopp, M. F.; Manne, K.; Saunders, K. O.; Edwards, R. J.; Haynes, B. F.; Henderson, R.; Acharya, P.

10.1101/2021.03.11.435037 — microbiology — Posted on 2021-03-15

2709 Sensitive visualization of SARS-CoV-2 RNA with CoronaFISH

Rensen, E. I.; Pietropaoli, S.; Mueller, F.; Weber, C.; Souquere, S.; Isnard, P.; Rabant, M.; Gibier, J.-B.; Simon-Loriere, E.; Rameix-Welti, M.-A.; Pierron, G.; Barba-Spaeth, G.; Zimmer, C.

10.1101/2021.02.04.429604 — microbiology — Posted on 2021-03-15

2710 Low ozone concentration and negative ions for rapid SARS-CoV-2 inactivation

De Forni, D.; Poddesu, B.; Cugia, G.; Gallizia, G.; La Licata, M.; Lisziewicz, J.; Chafouleas, J. G.; Lori, F.

10.1101/2021.03.11.434968 — microbiology — Posted on 2021-03-15

2711 SARS-CoV-2 variants resist antibody neutralization and broaden host ACE2 usage

Wang, R.; Zhang, Q.; Ge, J.; Ren, W.; Zhang, R.; Lan, J.; Ju, B.; Su, B.; Yu, F.; Chen, P.; Liao, H.; Feng, Y.; Li, X.; Shi, X.; Zhang, Z.; Zhang, F.; Ding, Q.; Zhang, T.; Wang, X.; Zhang, L.

10.1101/2021.03.09.434497 — immunology — Posted on 2021-03-15

2712 Total number and ratio of GABAergic neuron types in the mouse lateral and basal amygdala

Vereczki, V.; Muller, K.; Krizsan, E.; Mate, Z.; Fekete, Z.; Rovira-Esteban, L.; Veres, J.; Erdelyi, F.; Hajos, N.

10.1101/2021.03.15.435365 — neuroscience — Posted on 2021-03-15

2713 Brain areas associated with visual spatial attention display topographic organization during auditory spatial attention

Popov, T.; Gips, B.; Weisz, N.; Jensen, O.

10.1101/2021.03.15.435371 — neuroscience — Posted on 2021-03-15

2714 A novel soluble ACE2 protein totally protects from lethal disease caused by SARS-CoV-2 infection

Hassler, L.; Wysocki, J.; Gelarden, I.; Tomatsidou, A.; Nicoleascu, V.; Randall, G.; Henkin, J.; Yeldandi, A.; Batlle, D.

10.1101/2021.03.12.435191 — pathology — Posted on 2021-03-15

2715 In-situ fiducial markers for 3D correlative cryo- fluorescence and FIB-SEM imaging

Scher, N.; Rechav, K.; Paul-Gilloteaux, P.; Avinoam, O.

10.1101/2021.03.14.435311 — cell biology — Posted on 2021-03-15

2716 Phagocytic 'teeth' and myosin-II 'jaw' power target constriction during phagocytosis

Vorselen, D.; Barger, S. R.; Wang, Y.; Cai, W.; Theriot, J. A.; Gauthier, N. C.; Krendel, M.

10.1101/2021.03.14.435346 — cell biology — Posted on 2021-03-15

2717 A mechanistic model captures the emergence and implications of non-genetic heterogeneity and reversible drug resistance in ER+ breast cancer cells

Sahoo, S.; Mishra, A.; Kaur, H.; Hari, K.; Muralidharan, S.; Mandal, S.; Jolly, M. K.

10.1101/2021.03.14.435359 — cancer biology — Posted on 2021-03-15

2718 In vitro and in vivo comparison of the MRI glucoCEST properties between native glucose and 3OMG in a murine tumor model

Anemone, A. A.; Capozza, M.; Arena, F.; Zullino, S.; Bardini, P.; Terreno, E.; Longo, D. L.; Aime, S.

10.1101/2021.03.15.435387 — biophysics — Posted on 2021-03-15

2719 How do biofilms feel their environment?

Asp, M.; Tri Ho Thanh, M.; Gopinath, A.; Patteson, A. E.

10.1101/2021.03.15.435407 — biophysics — Posted on 2021-03-15

2720 Rational engineering of low temperature activity in thermoalkalophilic Geobacillus thermocatenulatus lipase

Wang, W.; Dasetty, S.; Sarupria, S.; Blenner, M.

10.1101/2021.03.14.435354 — biochemistry — Posted on 2021-03-15

2721 Community Evaluation of Glycoproteomics Informatics Solutions Reveals High-Performance Search Strategies of Glycopeptide Data

Kawahara, R.; Alagesan, K.; Bern, M.; Cao, W.; Chalkley, R. J.; Cheng, K.; Choo, M. S.; Edwards, N.; Goldman, R.; Hoffmann, M.; Hu, Y.; Huang, Y.; Kim, J. Y.; Kletter, D.; Liquet-Weiland, B.; Liu, M.; Mechref, Y.; Meng, B.; Neelamegham, S.; Nguyen-Khuong, T.; Nilsson, J.; Pap, A.; Park, G. W.; Parker, B. L.; Pegg, C. L.; Penninger, J. M.; Phung, T. K.; Pioch, M.; Rapp, E.; Sakalli, E.; Sanda, M.; Shulz, B. L.; Scott, N. E.; Sofronov, G.; Stadlmann, J.; Vakhrushev, S. Y.; Woo, C. M.; Wu, H.-Y.; Yang, P.; Ying, W.; Zhang, H.; Zhang, Y.; Zhao, J.; Zaia, J.; Haslam, S. M.; Palmisano, G.; Yoo, J. S

10.1101/2021.03.14.435332 — biochemistry — Posted on 2021-03-15

2722 Natural variants with 2D correlation genetics identify domains coordinating sarcomere proteins during contraction

Burghardt, T. P.

10.1101/2021.03.14.435341 — biochemistry — Posted on 2021-03-15

2723 Recombinant SARS-CoV-2 genomes are currently circulating at low levels

VanInsberghe, D.; Neish, A. S.; Lowen, A. C.; Koelle, K.

10.1101/2020.08.05.238386 — evolutionary biology — Posted on 2021-03-15

2724 Langerhans islets induce anti-tumor immunity at the expense of glycemic control and predict chemotherapy response in pancreatic cancer

Ahmed, A.; Charoentong, P.; Klotz, R.; Koehler, S.; Suarez-Carmona, M.; Valous, N. A.; Ferber, D.; Heikenwaelder, M.; Giese, N.; Hackert, T.; Klupp, F.; Schneider, M.; Schmidt, T.; Springfeld, C.; Tanriver, Y.; Falk, C. S.; Zitvogel, L.; Zoernig, I.; Jaeger, D.; Halama, N.

10.1101/2021.03.13.435100 — cancer biology — Posted on 2021-03-15

2725 Multiplexed single-cell proteomics using SCoPE2

Petelski, A. A.; Emmott, E.; Leduc, A.; Huffman, R. G.; Specht, H.; Perlman, D. H.; Slavov, N.

10.1101/2021.03.12.435034 — biochemistry — Posted on 2021-03-15

2726 AKAP79 enables calcineurin to directly suppress protein kinase A activity

Church, T. W.; Tewatia, P.; Hannan, S.; Antunes, J.; Eriksson, O.; Smart, T. G.; Hellgren Kotaleski, J.; Gold, M.

10.1101/2021.03.14.435320 — biochemistry — Posted on 2021-03-15

2727 Profiling epigenetic age in single cells

Trapp, A.; Kerepesi, C.; Gladyshev, V. N.

10.1101/2021.03.13.435247 — genomics — Posted on 2021-03-15

2728 Gene duplications and genomic conflict underlie major pulses of phenotypic evolution in gymnosperms

Stull, G. W.; Qu, X.-J.; Parins-Fukuchi, C.; Yang, Y.-Y.; Yang, J.-B.; Yang, Z.-Y.; Hu, Y.; Ma, H.; Soltis, P. S.; Soltis, D. E.; Li, D.-Z.; Smith, S. A.; Yi, T.-S.

10.1101/2021.03.13.435279 — evolutionary biology — Posted on 2021-03-15

2729 Co-variation between glucocorticoids, behaviour and immunity supports the pace-of-life syndrome hypothesis: an experimental approach

Carbillet, J.; Rey, B.; Palme, R.; Monestier, C.; Borger, L.; Lavabre, T.; Maublanc, M.-L.; Cebe, N.; Rames, J.-L.; Le Loc'h, G.; Wasniewski, M.; Rannou, B.; Gilot-Fromont, E.; Verheyden, H.

10.1101/2021.03.13.435238 — evolutionary biology — Posted on 2021-03-15

2730 A meta-analysis of single visit pollination effectiveness

Page, M. L.; Nicholson, C. C.; Brennan, R.; Britzman, A.; Hemberger, J.; Greer, J.; Kahl, H.; Muller, U.; Peng, Y.; Rosenberger, N.; Stuligross, C.; Wang, L.; Yang, L. H.; Williams, N. M.

10.1101/2021.03.12.432378 — ecology — Posted on 2021-03-15

2731 GPR15 in colon cancer development and anti-tumor immune responses.

NamKoong, H.; Lee, B.; Swaminathan, G.; Koh, S.-J.; Rogalla, S.; Mikhail, D. M.; Habtezion, A.

10.1101/2021.03.13.435189 — immunology — Posted on 2021-03-15

2732 Using synthetic MR images for field map-less distortion correction

Montez, D. F.; Van, A. N.; Miller, R. L.; Seider, N. A.; Marek, S.; Zheng, A.; Newbold, D. J.; Scheidter, K.; Feczko, E.; Perrone, A. J.; Miranda Dominguez, O.; Earl, E. A.; Kay, B. P.; Jha, A. K.; Sotiras, A.; Laumann, T. O.; Greene, D. J.; Gordon, E. M.; Tisdall, M. D.; van der Kouwe, A.; Fair, D. A.; Dosenbach, N. U. F.

10.1101/2021.03.13.435270 — neuroscience — Posted on 2021-03-15

2733 Contrast adaptation improves spatial integration

Pinchuk Yacobi, N.; Sagi, D.

10.1101/2021.03.14.435290 — neuroscience — Posted on 2021-03-15

2734 Discrete ripples reflect a spectrum of synchronous spiking activity in human association cortex

Tong, A. P. S.; Vaz, A. P.; Wittig, J. H.; Inati, S. K.; Zaghloul, K. A.

10.1101/2021.03.14.435276 — neuroscience — Posted on 2021-03-15

2735 The Neurodata Without Borders ecosystem for neurophysiological data science

Ruebel, O.; Tritt, A. J.; Ly, R.; Dichter, B. K.; Ghosh, S. S.; Niu, L.; Soltesz, I.; Svoboda, K.; Frank, L. M.; Bouchard, K.

10.1101/2021.03.13.435173 — neuroscience — Posted on 2021-03-15

2736 Individualized precision targeting of dorsal attention and default mode networks with rTMS in traumatic brain injury-associated depression

Siddiqi, S. H.; Kandala, S.; Hacker, C. D.; Trapp, N. T.; Leuthardt, E. C.; Carter, A. R.; Brody, D. L.

10.1101/2021.03.13.435127 — neuroscience — Posted on 2021-03-15

2737 Redox Buffering Capacity of Nanomaterials as an Index of ROS-based Therapeutics and Toxicity: A Preclinical Animal Study

Adhikari, A.; Mondal, S.; Das, M.; Ghosh, R.; Biswas, P.; Darbar, S.; Das, A. K.; Bhattacharya, S.; Pal, D.; Mallick, A. K.; Pal, S. K.

10.1101/2021.03.14.435286 — pharmacology and toxicology — Posted on 2021-03-15

2738 Redox Nanomedicine Cures Chronic Kidney Disease (CKD) by Mitochondrial Reconditioning

Adhikari, A.; Mondal, S.; Chatterjee, T.; Das, M.; Biswas, P.; Darbar, S.; Alessa, H.; Sayqal, A.; Ahmed, S. A.; Das, A. K.; Bhattacharyya, M.; Pal, S. K.

10.1101/2021.03.14.435287 — pharmacology and toxicology — Posted on 2021-03-15

2739 Detection of Chronic Wasting Disease prions in fetal tissues of free-ranging white-tailed deer

Mathiason, C. K.; Nalls, A. V.; McNulty, E. E.; Mayfield, A.; Crum, J. M.; Keel, M. K.; Hoover, E. A.; Ruder, M. G.

10.1101/2021.03.13.435248 — pathology — Posted on 2021-03-15

2740 SARS-CoV-2 Nsp8 N-terminal domain dimerizes and harbors autonomously folded elements

Trevino, M. A.; Pantoja-Uceda, D.; Laurents, D. V.; Mompean, M.

10.1101/2021.03.12.435186 — biophysics — Posted on 2021-03-15

2741 Spontaneous dimensional reduction and novel ground state degeneracy in a simple chain model

Skrbic, T.; Hoang, T. X.; Giacometti, A.; Maritan, A.; Banavar, J. R.

10.1101/2021.03.13.435258 — biophysics — Posted on 2021-03-15

2742 PlotMI: visualization of pairwise interactions and positional preferences learned by a deep learning model from sequence data

Hartonen, T.; Kivioja, T.; Taipale, J.

10.1101/2021.03.14.435285 — bioinformatics — Posted on 2021-03-15

2743 Dissolved oxygen minimally affects magnetic susceptibility in biologically relevant conditions

Fortier, V.; Levesque, I. R.

10.1101/2021.03.13.434266 — bioengineering — Posted on 2021-03-15

2744 Hülle-cell-mediated protection of fungal reproductive and overwintering structures against fungivorous animals

Liu, L.; Dirnberger, B.; Valerius, O.; Fekete-Szücs, E.; Harting, R.; Sasse, C.; Nordzieke, D. E.; Pöggeler, S.; Karlovsky, P.; Gerke, J.; Braus, G. H.

10.1101/2021.03.14.435325 — biochemistry — Posted on 2021-03-15

2745 Subcellular architecture and metabolic connection in the planktonic photosymbiosis between Collodaria (radiolarians) and their microalgae

Decelle, J.; Veronesi, G.; LeKieffre, C.; Gallet, B.; Chevalier, F.; Stryhanyuk, H.; Marro, S.; Ravanel, S.; Tucoulou, R.; Schieber, N.; Finazzi, G.; Schwab, Y.; Musat, N.

10.1101/2021.03.13.435225 — ecology — Posted on 2021-03-15

2746 Evaluation of the OsTIR1 and AtAFB2 AID systems for chromatin protein degradation in mammalian cells

Yunusova, A.; Smirnov, A.; Shnaider, T.; Afonnikova, S.; Battulin, N.

10.1101/2021.03.15.435352 — molecular biology — Posted on 2021-03-15

2747 Targeting cellular DNA damage responses in cancer: An in vitro-calibrated agent-based model simulating monolayer and spheroid treatment responses to ATR-inhibiting drugs

Hamis, S. J.; Yates, J.; Chaplain, M. A.; Powathil, G. G.

10.1101/841270 — cancer biology — Posted on 2021-03-15

2748 A vascularized tumoroid model for human glioblastoma angiogenesis

Stavropoulou-Tatla, A.; Justin, A. W.; Watts, C.; Markaki, A. E.

10.1101/2021.02.05.429930 — bioengineering — Posted on 2021-03-15

2749 Management programs as a key factor for genetic conservation of small populations : The case of French local chicken breeds

Restoux, G.; Rognon, X.; Vieaud, A.; Guemene, D.; Petitjean, F.; Rouger, R.; Brard-Fudulea, S.; Lubac-Paye, S.; Chiron, G.; Tixier-Boichard, M.

10.1101/2021.03.12.435064 — genetics — Posted on 2021-03-15

2750 Cell cycle-independent integration of stress signals promotes Non-G1/G0 cellular quiescence

Arguello-Miranda, O.; Marchand, A.; Kennedy, T.; Russo, M. A.; Noh, J.

10.1101/2021.03.13.434817 — cell biology — Posted on 2021-03-15

2751 A malaria parasite phospholipid flippase safeguards midgut traversal of ookinetes for mosquito transmission

Yang, Z.; Shi, Y.; Cui, H.; Yang, S.; Gao, H.; Yuan, J.

10.1101/2021.03.14.435214 — microbiology — Posted on 2021-03-15

2752 Evaluation of UV-A LED technology on the reduction of spiked aflatoxin B1 and aflatoxin M1 in whole milk: toxicity analysis using liver hepatocellular cells

Kurup, A. H.; Patras, A.; Pendyala, B.; Vergne, M. J.; Bansode, R. R.

10.1101/2021.03.14.435353 — microbiology — Posted on 2021-03-15

2753 Preferential selection and contribution of non-structural protein 1 (NS1) to the efficient transmission of the panzootic avian influenza H5N8 2.3.4.4 clades A and B viruses in chickens and ducks

Blaurock, C.; Breithaupt, A.; Scheibner, D.; Bagato, O.; Karger, A.; Mettenleiter, T. C.; Abdelwhab, E. M.

10.1101/2021.03.14.435362 — microbiology — Posted on 2021-03-15

2754 A population of neurons that produce hugin and express the diuretic hormone 44 receptor gene projects to the corpora allata in Drosophila melanogaster

Mizuno, Y.; Imura, E.; Kurogi, Y.; Shimada-Niwa, Y.; Kondo, S.; Tanimoto, H.; Hueckesfeld, S.; Pankratz, M.; Niwa, R.

10.1101/2021.03.15.435215 — zoology — Posted on 2021-03-15

2755 Reduction of a stochastic model of gene expression: Lagrangian dynamics gives acces to basins of attraction as cell types and metastability

Ventre, E.; Espinasse, T.; Brehier, C.-E.; Calvez, V.; Lepoutre, T.; Gandrillon, O.

10.1101/2020.09.04.283176 — systems biology — Posted on 2021-03-15

2756 Rootstocks influence the response of ripening grape berries to leafroll associated viruses

Vondras, A. M.; Lerno, L.; Massonnet, M.; Minio, A.; Rowhani, A.; Liang, D.; Quiroz, D.; Figueroa-Balderas, R.; Golino, D.; Ebeler, S. E.; Al Rwanhnih, M.; Cantu, D.

10.1101/2021.03.14.434319 — plant biology — Posted on 2021-03-15

2757 The hidden effects of agrochemicals on plant metabolism and root-associated microorganisms

Cesco, S.; Lucini, L.; Miras-Moreno, B.; Borruso, L.; Mimmo, T.; Pii, Y.; Puglisi, E.; Spini, G.; Taskin, E.; Tiziani, R.; Zangrillo, S.; Trevisan, M.

10.1101/2021.03.14.435313 — plant biology — Posted on 2021-03-15

2758 TPX2-dependent spindle positioning dictates division site during asymmetric cell division in moss gametophores

Kozgunova, E.; Yoshida, M. W.; Reski, R.; Goshima, G.

10.1101/2020.03.03.975557 — plant biology — Posted on 2021-03-15

2759 Gene body methylation mediates epigenetic inheritance of plant traits

Shahzad, Z.; Moore, J. D.; Zilberman, D.

10.1101/2021.03.15.435374 — evolutionary biology — Posted on 2021-03-15

2760 A potential clue for the application of prime editing in tomato, a dicot plant

Vu, T. V.; Kim, J.; Das, S.; Kim, J.-Y.

10.1101/2021.03.15.435378 — molecular biology — Posted on 2021-03-15

2761 Differential Roles of Positive and Negative Valence Systems in the Development of Post-Traumatic Stress Psychopathology

Ben-Zion, Z.; Shany, O.; Admon, R.; Keynan, N. J.; Avisdris, N.; Reznik Balter, S.; Shalev, A. Y.; Liberzon, I.; Hendler, T.

10.1101/2021.03.08.434335 — neuroscience — Posted on 2021-03-15

2762 immuneML: an ecosystem for machine learning analysis of adaptive immune receptor repertoires

Pavlovic, M.; Scheffer, L.; Motwani, K.; Kanduri, C.; Kompova, R.; Vazov, N.; Waagan, K.; Bernal, F. L. M.; Costa, A. A.; Corrie, B.; Akbar, R.; Al Hajj, G. S.; Balaban, G.; Brusko, T. M.; Chernigovskaya, M.; Christley, S.; Cowell, L. G.; Frank, R.; Grytten, I.; Gundersen, S.; Hobaek Haff, I.; Hochreiter, S.; Hovig, E.; Hsieh, P.-H.; Klambauer, G.; Kuijjer, M. L.; Lund-Andersen, C.; Martini, A.; Minotto, T.; Pensar, J.; Rand, K.; Riccardi, E.; Robert, P. A.; Rocha, A.; Slabodkin, A.; Snapkov, I.; Sollid, L. M.; Titov, D.; Weber, C. R.; Widrich, M.; Yaari, G.; Greiff, V.; Sandve, G. K.

10.1101/2021.03.08.433891 — bioinformatics — Posted on 2021-03-15

2763 Hydroxyl-radical scavenging activity of hydrogen does not significantly contribute to its biological function

Li, Q.; Xie, F.; Yi, Y.; Zhao, P.; Zhang, X.; Zhang, X.; Zhang, X.; Ma, X.

10.1101/2021.03.13.435216 — biochemistry — Posted on 2021-03-15

2764 Management programs as a key factor for genetic conservation of small populations : The case of French local chicken breeds

Restoux, G.; Rognon, X.; Vieaud, A.; Guemene, D.; Petitjean, F.; Rouger, R.; Brard-Fudulea, S.; Lubac, S.; Chiron, G.; Tixier-Boichard, M.

10.1101/2021.03.12.435064 — genetics — Posted on 2021-03-15

2765 Systematic exploration of Escherichia coli phage-host interactions with the BASEL phage collection

Maffei, E.; Shaidullina, A.; Burkolter, M.; Druelle, V.; Willi, L.; Estermann, F.; Michaelis, S.; Hilbi, H.; Thaler, D. S.; Harms, A.

10.1101/2021.03.08.434280 — microbiology — Posted on 2021-03-15

2766 GABA relates to functional connectivity changes and retention in visuomotor adaptation

Nettekoven, C. R.; Brady, S.; Clarke, W. T.; Emir, U.; Levenstein, J.; Petitet, P.; Panouilleres, M. T. N.; Bachtiar, V.; O'Shea, J.; Johansen-Berg, H.; Jenkinson, N.; Stagg, C.

10.1101/2020.12.22.423981 — neuroscience — Posted on 2021-03-15

2767 Genomic signature of shifts in selection and alkaline adaptation in highland fish

Tong, C.; Li, M.; Tang, Y.; Zhao, K.

10.1101/2020.12.23.424241 — evolutionary biology — Posted on 2021-03-14

2768 Paired feed-forward excitation with delayed inhibition allows high frequency computations across brain regions

Cao, A.; Van Hooser, S. D.

10.1101/2021.03.13.435272 — neuroscience — Posted on 2021-03-14

2769 Detecting changes in dynamical structures in synchronous neural oscillations using probabilistic inference

Yokoyama, H.; Kitajo, K.

10.1101/2020.10.13.335356 — neuroscience — Posted on 2021-03-14

2770 FlywheelTools: Data Curation and Manipulation on the Flywheel Platform

Tapera, T. M.; Cieslak, M.; Bertolero, M.; Adembimpe, A.; Aguirre, G. K.; Butler, E. R.; Cook, P. A.; Davila, D.; Elliot, M. A.; Linguiti, S.; Murtha, K.; Tackett, W.; Detre, J. A.; Satterthwaite, T. D.

10.1101/2021.03.12.434998 — bioinformatics — Posted on 2021-03-14

2771 Petabase-scale sequence alignment catalyses viral discovery

Edgar, R. C.; Taylor, J.; Lin, V.; Altman, T.; Barbera, P.; Meleshko, D.; Lohr, D.; Novakovsky, G.; Buchfink, B.; Al-Shayeb, B.; Banfield, J.; de la Pena, M.; Korobeynikov, A.; Chikhi, R.; Babaian, A.

10.1101/2020.08.07.241729 — bioinformatics — Posted on 2021-03-14

2772 Systems genetics analyses in Diversity Outbred mice inform human bone mineral density GWAS and identify Qsox1 as a novel determinant of bone strength

Al-Barghouthi, B. M.; Mesner, L. M.; Calabrese, G. M.; Brooks, D. J.; Tommasini, S. M.; Bouxsein, M. L.; Horowitz, M. C.; Rosen, C. J.; Nguyen, K.; Haddox, S.; Farber, E. A.; Onengut-Gumuscu, S.; Pomp, D.; Farber, C.

10.1101/2020.06.24.169839 — genetics — Posted on 2021-03-14

2773 The anterior Hox gene ceh-13 and elt-1/GATA activate the posterior Hox genes nob-1 and php-3 to specify posterior lineages in the C. elegans embryo

Murray, J. I.; Preston, E.; Crawford, J. P.; Rumley, J. D.; Amom, P.; Anderson, B. D.; Sivaramakrishnan, P.; Patel, S. D.; Bennett, B. A.; Lavon, T. D.; Peng, F.; Zacharias, A. L.

10.1101/2021.02.09.430385 — genetics — Posted on 2021-03-14

2774 Force-dependent activation of actin elongation factor mDia1 protects the cytoskeleton from mechanical damage and facilitates stress fiber repair.

Valencia, F. R.; Sandoval, E.; Liu, J.; Plotnikov, S. V.

10.1101/2021.02.08.430278 — cell biology — Posted on 2021-03-14

2775 Gut regulates brain synaptic assembly through neuroendocrine signaling pathway

Shi, Y.; Qin, L.; Shao, Z.

10.1101/2021.01.29.428811 — neuroscience — Posted on 2021-03-14

2776 Non-linearity matters: a deep learning solution to the generalization of hidden brain patterns across population cohorts

Zabihi, M.; Kia, S. M.; Wolfers, T.; Dinga, R.; Llera, A.; Bzdok, D.; Beckmann, C.; marquand, A.

10.1101/2021.03.10.434856 — neuroscience — Posted on 2021-03-14

2777 Cryo-EM structure of an elusive pre-transport intermediate of the multidrug transporter BmrCD reveals modes of asymmetric drug binding

Thaker, T. M.; Mishra, S.; Zhou, W.; Faraldo-Gomez, J.; Mchaourab, H.; Tomasiak, T. M.

10.1101/2021.03.13.435271 — biophysics — Posted on 2021-03-14

2778 Discovery of indole-modified aptamers for highly specific recognition of protein glycoforms

Yoshikawa, A.; Rangel, A. E.; Feagin, T.; Chun, E.; Wan, L.; Li, A.; Moekl, L.; Eisenstein, M.; Pitteri, S.; Soh, H. T.

10.1101/2021.03.13.435263 — bioengineering — Posted on 2021-03-14

2779 Fracture Mechanics of Human Blood Clots: Measurements of Toughness and Critical Length scales

Liu, S.; Bao, G.; Ma, Z.; Kastrup, C.; Li, J.

10.1101/2021.03.13.435277 — bioengineering — Posted on 2021-03-14

2780 Massively parallel characterization of CYP2C9 variant enzyme activity and abundance

Amorosi, C. J.; Chiasson, M. A.; McDonald, M. G.; Wong, L. H.; Sitko, K. A.; Boyle, G.; Kowalski, J. P.; Rettie, A. E.; Fowler, D. M.; Dunham, M. J.

10.1101/2021.03.12.435209 — genomics — Posted on 2021-03-14

2781 Heat wave event facilitates defensive responses in invasive C3 plant Ambrosia artemisiifolia L. under elevated CO2 concentration to the detriment of insect herbivores

Zhenya, T.; Chao, M.; Chenchen, Z.; Yan, Z.; Xuyuan, G.; Zhenqi, T.; Guo, J.; Zhongshi, Z.

10.1101/2021.03.13.435250 — ecology — Posted on 2021-03-14

2782 RNA-BINDING PROTEINS DIRECT MYOGENIC CELL FATE DECISIONS

Wheeler, J. R.; Whitney, O. N.; Vogler, T. O.; Nguyen, E. D.; Pawlikowski, B.; Lester, E.; Cutler, A.; Elston, T.; Dalla Betta, N.; Parker, K. R.; Yost, K.; Vogel, H.; Rando, T. A.; Chang, H. Y.; Johnson, A. M.; Parker, R.; Olwin, B. B.

10.1101/2021.03.14.435333 — molecular biology — Posted on 2021-03-14

2783 Discovery of viral myosin genes with complex evolutionary history within plankton

Kijima, S.; Delmont, T. O.; Miyazaki, U.; Gaia, M.; Endo, H.; Ogata, H.

10.1101/2021.03.14.435220 — microbiology — Posted on 2021-03-14

2784 Crosstalk between enterocytes and innate lymphoid cells drives early IFN-g-mediated control of Cryptosporidium

Gullicksrud, J.; Sateriale, A.; Engiles, J. B.; Gibson, A.; Shaw, S.; Hutchins, Z.; Martin, L.; Christian, D. A.; Taylor, G. A.; Yamamoto, M.; Beiting, D. P.; Striepen, B.; Hunter, C.

10.1101/2021.03.13.435244 — immunology — Posted on 2021-03-14

2785 Selective Corticofugal Modulation on Sound Processing in Auditory Thalamus of Awake Marmosets

Zhang, Y.; Wang, X.; Zhu, L.; Bai, S.; Li, R.; Sun, H.; Qi, R.; Cai, R.; Li, M.; Jia, G.; Schriver, K. E.; Li, X.; Gao, L.

10.1101/2021.03.13.435231 — neuroscience — Posted on 2021-03-14

2786 A completely resolved phylogenetic tree of British spiders

Breitling, R.

10.1101/2021.03.12.434792 — zoology — Posted on 2021-03-14

2787 Updating the steady state model of C4 photosynthesis

von Caemmerer, S.

10.1101/2021.03.13.435281 — plant biology — Posted on 2021-03-14

2788 In Vitro Assessment of Efficacy and Cytotoxicity of Prunus africana Extracts on Prostate Cancer C4-2 Cells

Asuzu, P. C.; Aryee, A. N. A.; Trompeter, N.; Mann, Y.; Besong, S. A.; Duncan, R. L.; Cooper, C. R.

10.1101/2021.03.14.435338 — cancer biology — Posted on 2021-03-14

2789 A Serpin27A-dependent Toll Signaling Underlies Host Genetics of Cancer Resistance in Drosophila

Singh, R.; Harsh, S.; Bajpai, A.; Pal, S.; Pandey, R. K.; Sinha, P.

10.1101/2021.03.13.435228 — cancer biology — Posted on 2021-03-14

2790 Primordial capsid and spooled ssDNA genome structures penetrate ancestral events of eukaryotic viruses

Munke, A.; Kimura, K.; Tomaru, Y.; Wang, H.; Yoshida, K.; Mito, S.; Hongo, Y.; Okamoto, K.

10.1101/2021.03.14.435335 — biophysics — Posted on 2021-03-14

2791 Folds induced by multiple parallel or antiparallel double-helices: (pseudo)knotting of single-stranded RNA.

Hyde, S. T.

10.1101/2021.03.12.435210 — biophysics — Posted on 2021-03-14

2792 MCKAT, a multi-dimensional copy numbervariant kernel association test

Maus Esfahani, N.; Catchpoole, D.; Khan, J.; Kennedy, P. J.

10.1101/2021.03.13.435274 — bioinformatics — Posted on 2021-03-14

2793 Hydroxyl-radical scavenging activity of hydrogen does not significantly contribute to its biological function

Li, Q.; Xie, F.; Yi, Y.; Zhao, P.; Zhang, X.; Zhang, X.; Zhang, X.; Ma, X.

10.1101/2021.03.13.435216 — biochemistry — Posted on 2021-03-14

2794 Accurate analysis of short read sequencing in complex genomes: A case study using QTL-seq to target blanchability in peanut (Arachis hypogaea)

Korani, W.; O'Connor, D.; Chu, Y.; Chavarro, C.; Ballen, C.; Ozias-Akins, P.; Wright, G.; Clevenger, J.

10.1101/2021.03.13.435236 — genomics — Posted on 2021-03-14

2795 Intergenerational niche differentiation in filmy ferns (Hymenophyllaceae)

Nitta, J. H.; Watkins, J. E.; Holbrook, N. M.; Wang, T.; Davis, C. C.

10.1101/2021.03.12.435213 — ecology — Posted on 2021-03-14

2796 Svep1 stabilizes developmental vascular anastomosis in reduced flow conditions.

Coxam, B.; Padberg, Y.; Maier, K.; Jung, S.; Bartels-Klein, E.; Szymborska, A.; Finotto, L.; Schulte-Merker, S.; Gerhardt, H.

10.1101/2021.03.13.435246 — developmental biology — Posted on 2021-03-14

2797 A Creb3-Like Transcription Factor Coordinates ER Function uponFood Intake to Regulate Lipid Metabolism

Khan, H. A.; Toh, M.; Schauer, T.; Beresford, R. J.; Ortega Prieto, P.; Postic, C.; Margulies, C. E.

10.1101/2021.03.13.435227 — cell biology — Posted on 2021-03-14

Iijima, H.; Gilmer, G.; Wang, K.; Bean, A.; He, Y.; Lin, H.; Evans, C.; Ambrosio, F.

10.1101/2021.03.13.434679 — molecular biology — Posted on 2021-03-14

2799 Changes and composition of microbial community during aerobic composting of household food waste

Jin, Z.-H.; Lu, T.; Feng, W.; Jin, Q.; Wu, Z.; Yang, Y.

10.1101/2021.03.12.435218 — microbiology — Posted on 2021-03-14

2800 Efficacy of Anti-Staphylococcal Lysin, LSVT-1701, in Combination with Daptomycin in Experimental Left-Sided Infective Endocarditis Due to Methicillin-Resistant Staphylococcus aureus (MRSA)

Huang, D.; Gaukel, E.; Kerzee, N.; Borroto-Esoda, K.; Lowry, S.; Xiong, Y. Q.; Abdelhady, W.; Bayer, A.

10.1101/2021.03.12.435219 — microbiology — Posted on 2021-03-14

2801 Embryo Lethality Assay for Evaluating Virulence of Isolates from Bacterial Chondronecrosis with Osteomyelitis in Broilers

Ekesi, N. S.; Hasan, A.; Parveen, A.; Shwani, A.; Rhoads, D. D.

10.1101/2021.03.12.435217 — microbiology — Posted on 2021-03-14

2802 Ozone nanobubble treatments improve survivability of Nile tilapia (Oreochromis niloticus) challenged with a pathogenic multidrug-resistant Aeromonas hydrophila

Le, D. T.; Nguyen, L. V.; Dong, H. T.; Rodkhum, C.; St. Hilaire, S.; Senapin, S.; Sangpo, P.

10.1101/2021.03.14.435289 — microbiology — Posted on 2021-03-14

2803 PD-1 dependent expansion of Amphregulin+FOXP3+ cells is associated with oral immune dysfunction in HIV patients on therapy

Pandiyan, P.

10.1101/2021.03.13.435273 — immunology — Posted on 2021-03-14

2804 Increasing stimulus similarity drives nonmonotonic representational change in hippocampus

Wammes, J. D.; Norman, K. A.; Turk-Browne, N. B.

10.1101/2021.03.13.435275 — neuroscience — Posted on 2021-03-14

2805 Independent mechanisms underlie the protective effect of dietary polyunsaturated fatty acid supplementation and G&alphaz deficiency on the early type 1 diabetes phenotype of Non-obese diabetic (NOD) mice

Fenske, R. J.; Wienkes, H. N.; Peter, D. C.; Schaid, M. D.; Pennati, A.; Galipeau, J.; Kimple, M. E.

10.1101/2021.03.13.435254 — physiology — Posted on 2021-03-14

2806 Increased Risk for Cerebral Small Vessel Disease is Associated with Quantitative Susceptibility Mapping in HIV Infected and Uninfected Individuals

Murray, K. D.; Uddin, M. N.; Tivarus, M. E.; Sahin, B.; Wang, H. Z.; Singh, M. V.; Qiu, X.; Wang, L.; Spincemaille, P.; Wang, Y.; Zhong, J.; Maggirwar, S. B.; Schifitto, G.

10.1101/2021.03.13.435243 — pathology — Posted on 2021-03-14

2807 Systematic exploration of Escherichia coli phage-host interactions with the BASEL phage collection

Maffei, E.; Shaidullina, A.; Burkolter, M.; Druelle, V.; Willi, L.; Estermann, F.; Michaelis, S.; Hilbi, H.; Thaler, D. S.; Harms, A.

10.1101/2021.03.08.434280 — microbiology — Posted on 2021-03-14

2808 Clomipramine suppresses ACE2-mediated SARS-CoV-2 entry

Kato, Y.; Yamada, S.; Nishiyama, K.; Satsuka, A.; Re, S.; Tomokiyo, D.; Lee, J. M.; Tanaka, T.; Nishimura, A.; Yonemitsu, K.; Asakura, H.; Ibuki, Y.; Imai, Y.; Kamiya, N.; Mizuguchi, K.; Kusakabe, T.; Kanda, Y.; Nishida, M.

10.1101/2021.03.13.435221 — pharmacology and toxicology — Posted on 2021-03-14

2809 Mouse Single Islet β Cell Transcriptomics Reveal Sexually Dimorphic Transcriptomes and Type 2 Diabetes Genes

Liu, G.; Li, Y.; Zhang, T.; Li, M.; Li, S.; He, Q.; Liu, S.; Xu, M.; Xiao, T.; Zhen, S.; Shi, W.; Li, W.

10.1101/2020.09.22.307421 — bioinformatics — Posted on 2021-03-14

2810 Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex

Malone, B.; Chen, J.; Wang, Q.; Llewellyn, E.; Choi, Y. J.; Olinares, P. D. B.; Cao, X.; Hernandez, C.; Eng, E. T.; Chait, B. T.; Shaw, D. E.; Landick, R.; Darst, S. A.; Campbell, E. A.

10.1101/2021.03.13.435256 — biochemistry — Posted on 2021-03-14

2811 Selection maintains protein interactome resilience in the long-term evolution experiment with Escherichia coli

Maddamsetti, R.

10.1101/2021.01.20.427477 — evolutionary biology — Posted on 2021-03-14

2812 Leaf economics explained by optimality principles

Wang, H.; Prentice, I. C.; Wright, I. J.; Qiao, S.; Xu, X.; Kikuzawa, K.; Stenseth, N. C.

10.1101/2021.02.07.430028 — ecology — Posted on 2021-03-14

2813 CLN5 and CLN3 function as a complex to regulate endolysosome function

Yasa, S.; Sauvageau, E.; Modica, G.; Lefrancois, S.

10.1101/2020.12.24.423824 — cell biology — Posted on 2021-03-14

2814 The functional connectivity of the human claustrum according to the Human Connectome Project database

Rodriguez-Vidal, L.; Alcauter, S.; Barrios, F. A.

10.1101/705350 — neuroscience — Posted on 2021-03-14

2815 Mean-field modeling of brain-scale dynamics for the evaluation of EEG source-space networks

Allouch, S.; Yochum, M.; Kabbara, A.; Duprez, J.; Khalil, M.; Wendling, F.; Hassan, M.; Modolo, J.

10.1101/2020.09.16.299305 — neuroscience — Posted on 2021-03-14

2816 Model balancing: in search of consistent metabolic states and in-vivo kinetic constants

Liebermeister, W.; Noor, E.

10.1101/2019.12.23.887166 — systems biology — Posted on 2021-03-14

2817 Intra and inter-annual climatic conditions have stronger effect than grazing intensity on root growth of permanent grasslands

Picon-Cochard, C.; Vassal, N.; Martin, R.; Herfurth, D.; Note, P.; Louault, F.

10.1101/2020.08.23.263137 — ecology — Posted on 2021-03-14

2818 Human AdV-20-42-42, a promising novel adenoviral vector for gene therapy and vaccine product development

Ballmann, M. Z.; Raus, S.; Engelhart, R.; Kajan, G. L.; van der Zalm, C.; Papp, T.; John, L.; Khan, S.; Custers, J.; Bakker, W. A. M.; van der Schaar, H. M.; Arnberg, N.; Lemckert, A.; Havenga, M.; Baker, A. H.

10.1101/2021.03.11.435055 — immunology — Posted on 2021-03-14

2819 Non-linearity matters: a deep learning solution to the generalization of hidden brain patterns across population cohorts

Zabihi, M.; Kia, S. M.; Wolfers, T.; Dinga, R.; Llera, A.; Bzdok, D.; Beckmann, C.; marquand, A.

10.1101/2021.03.10.434856 — neuroscience — Posted on 2021-03-14

2820 Engaging the complexity of diet and healthy aging in humans

Senior, A. M.; Legault, V.; Lavoie, F. B.; Presse, N.; Gaudreau, P.; Turcot, V.; Raubenheimer, D.; Le Couteur, D. G.; Simpson, S.; Cohen, A. A.

10.1101/2021.03.12.435077 — bioinformatics — Posted on 2021-03-14

2821 Idefix: identifying accidental sample mix-ups in biobanks using polygenic scores

Warmerdam, R. C. A.; Lanting, P.; LifeLines Cohort Study, ; Deelen, P.; Franke, L.

10.1101/2021.03.12.435080 — bioinformatics — Posted on 2021-03-14

2822 Integrative Analysis of Sorghum Bicolor Green Prop Roots Under Elevated CO2 and Water Deficit Conditions

Rodrigues, T. d. S.; Arge, L. W. P.; Travassos-Lins, J.; Guedes, F. A. d. F.; de Souza, A. P.; Cocuron, J.-C.; Buckeridge, M. S.; Grossi de Sa, M. F.; Alves-Ferreira, M.

10.1101/2021.03.12.435150 — molecular biology — Posted on 2021-03-14

2823 Symmetry processing in the macaque visual cortex

Audurier, P.; Hejja-Brichard, Y.; De Castro, V.; Kohler, P. J.; Norcia, A.; Durand, J.-B.; Cottereau, B. R.

10.1101/2021.03.13.435181 — neuroscience — Posted on 2021-03-13

2824 A tunable population timer in multicellular consortia

Toscano-Ochoa, C.; Garcia-Ojalvo, J.

10.1101/2020.10.24.353334 — synthetic biology — Posted on 2021-03-13

2825 Improving oligo-conjugated antibody signal in multimodal single-cell analysis

Buus, T. B.; Herrera, A.; Ivanova, E.; Mimitou, E.; Cheng, A.; Herati, R.; Papagiannakopoulos, T.; Smibert, P.; Odum, N.; Koralov, S. B.

10.1101/2020.06.15.153080 — genomics — Posted on 2021-03-13

2826 Variability in porcine microRNA genes and its association with mRNA expression and lipid phenotypes

Marmol-Sanchez, E.; Luigi-Sierra, M. G.; Castello, A.; Guan, D.; Quintanilla, R.; Tonda, R.; Amills, M.

10.1101/2020.04.17.038315 — genomics — Posted on 2021-03-13

2827 Crosstalk in oxygen homeostasis networks: SKN-1/NRF inhibits the HIF-1 hypoxia-inducible factor in Caenorhabditis elegans

Feng, D.; Zhai, Z.; Shao, Z.; Zhang, Y.; Powell-Coffman, J. A.

10.1101/2021.03.12.435071 — genetics — Posted on 2021-03-13

2828 Population monitoring of snow leopards using camera trapping in Naryn State Reserve, Kyrgyzstan, between 2016 and 2019

Rode, J.; Lambert, C.; Marescot, L.; Chaix, B.; Beesau, J.; Bastian, S.; Kyrbashev, J.; Cabanat, A.-L.

10.1101/2021.02.24.432722 — ecology — Posted on 2021-03-13

2829 Reverse complementary matches simultaneously promote both back-splicing and exon-skipping

Cao, D.

10.1101/2021.02.28.433292 — molecular biology — Posted on 2021-03-13

2830 A Self-Replicating Radiation-Shield for Human Deep-Space Exploration: Radiotrophic Fungi can Attenuate Ionizing Radiation aboard the International Space Station

Shunk, G. K.; Gomez, X. R.; Averesch, N. J. H.

10.1101/2020.07.16.205534 — microbiology — Posted on 2021-03-13

2831 Spontaneous Escherichia coli persisters with week-long survival dynamics and lasting memory of a short starvation pulse

Svenningsen, M. S.; Svenningsen, S. L.; Sorensen, M. A.; Mitarai, N.

10.1101/2020.09.17.301598 — microbiology — Posted on 2021-03-13

2832 PulseNet international: the missing link between PFGE and WGS

Adam, I. E.-k. M.

10.1101/2021.03.08.434411 — microbiology — Posted on 2021-03-13

Petitet, P.; Spitz, G.; Emir, U. E.; Johansen-Berg, H.; O'Shea, J.

10.1101/2020.12.03.410308 — neuroscience — Posted on 2021-03-13

2834 GWAS-associated variants, non-genetic factors, and transient transcriptome in Multiple Sclerosis etiopathogenesis: a colocalization analysis

Umeton, R.; Bellucci, G.; Bigi, R.; Romano, S.; Buscarinu, M. C.; Renie', R.; Rinaldi, V.; Pizzolato Umeton, R.; Morena, E.; Romano, C.; Mechelli, R.; Salvetti, M.; Ristori, G.

10.1101/2021.03.12.434773 — neuroscience — Posted on 2021-03-13

2835 THINGSvision: a Python toolbox for streamlining the extraction of activations from deep neural networks

Muttenthaler, L.; Hebart, M. N.

10.1101/2021.03.11.434979 — neuroscience — Posted on 2021-03-13

2836 Embryo development in Carica papaya Linn.

Benavides-Acevedo, M.; Bolanos-Villegas, P.

10.1101/2021.03.11.434975 — plant biology — Posted on 2021-03-13

2837 Cancer-specific overmethylation of histone H3 lysines is linked with methionine addiction and malignancy

Yamamoto, J.; Inubushi, S.; Han, Q.; Tashiro, Y.; Sun, Y.; Sugisawa, N.; Hamada, K.; Nishino, H.; Aoki, Y.; Miyake, K.; Matsuyama, R.; Bouvet, M.; Endo, I.; Hoffman, R. M.

10.1101/2020.12.04.412437 — cancer biology — Posted on 2021-03-13

2838 PalaCell2D: A framework for detailed tissue morphogenesis

Conradin, R.; Coreixas, C.; Latt, J.; Chopard, B.

10.1101/2021.01.30.428940 — bioinformatics — Posted on 2021-03-13

2839 SGI: Automatic clinical subgroup identification in omics datasets

Buyukozkan, M.; Suhre, K.; Krumsiek, J.

10.1101/2021.03.12.435108 — bioinformatics — Posted on 2021-03-13

2840 Linear B-cell epitope prediction for in silico vaccine design: a performance review of methods available via command-line interface

Galanis, K. A.; Nastou, K. C.; Papandreou, N. C.; Petichakis, G. N.; Pigis, D.; Iconomidou, V. A.

10.1101/833418 — bioinformatics — Posted on 2021-03-13

2841 Neural networks to learn protein sequence-function relationships from deep mutational scanning data

Gelman, S.; Fahlberg, S. A.; Heinzelman, P.; Romero, P. A.; Gitter, A.

10.1101/2020.10.25.353946 — bioinformatics — Posted on 2021-03-13

2842 Whole-proteome Tree of Insects: Grouping and phylogeny without sequence alignment

Choi, J.; Kim, B.-J.; Kim, S.-H.

10.1101/2020.07.11.198689 — evolutionary biology — Posted on 2021-03-13

2843 Molecular signatures of resource competition: clonal interference favors ecological diversification and can lead to incipient speciation

Amicone, M.; Gordo, I.

10.1101/2020.11.20.391151 — evolutionary biology — Posted on 2021-03-13

2844 Seeding of outbreaks of COVID-19 by contaminated fresh and frozen food

Fisher, D.; Reilly, A.; Kang Eng Zheng, A.; Cook, A. R.; Anderson, D.

10.1101/2020.08.17.255166 — microbiology — Posted on 2021-03-13

2845 Resistance to aztreonam in combination with non-β-lactam β-lactamase inhibitors due to the layering of mechanisms in Escherichia coli identified following mixed culture selection.

Cheung, C. H. P.; Dulyayangkul, P.; Heesom, K. J.; Avison, M.

10.1101/615336 — microbiology — Posted on 2021-03-13

2846 Motor resonance is modulated by an object's weight distribution

Rens, G.; Orban de Xivry, J.-J.; Davare, M.; van Polanen, V.

10.1101/2020.10.11.335000 — neuroscience — Posted on 2021-03-13

2847 Cortical depth-dependent human fMRI of resting-state networks using EPIK

Pais-Roldan, P.; Yun, S. D.; Palomero-Gallagher, N.; Shah, J. N.

10.1101/2020.12.07.414144 — neuroscience — Posted on 2021-03-13

2848 Development of a pest threshold decision support system for minimising damage to winter wheat from wheat bulb fly, Delia coarctata

Leybourne, D. J.; Storer, K. E.; Berry, P.; Ellis, S.

10.1101/2021.03.13.435242 — plant biology — Posted on 2021-03-13

2849 Programmed mechano-chemical coupling in reaction-diffusion active matter

Senoussi, A.; Galas, J.-C.; Estevez-Torres, A.

10.1101/2021.03.13.435232 — biophysics — Posted on 2021-03-13

2850 DeepLncLoc: a deep learning framework for long non-coding RNA subcellular localization prediction based on subsequence embedding

Zeng, M.; Wu, Y.; Lu, C.; Zhang, F.; Wu, F.-x.; Li, M.

10.1101/2021.03.13.435245 — bioinformatics — Posted on 2021-03-13

2851 Host phenology drives the evolution of intermediate parasite virulence

MacDonald, H.; Akcay, E.; Brisson, D.

10.1101/2021.03.13.435259 — evolutionary biology — Posted on 2021-03-13

2852 Using recent baselines as benchmarks for megafauna restoration places an unfair burden on the Global South

Monsarrat, S.; Svenning, J.-C.

10.1101/2021.03.13.435233 — ecology — Posted on 2021-03-13

2853 16S rRNA Gene Amplicon Profiling of the New Zealand parasitic blowfly Calliphora vicina.

Palevich, N.; Maclean, P. H.; Carvalho, L.; Jauregui, R.

10.1101/2021.03.12.435192 — molecular biology — Posted on 2021-03-13

2854 Temporally distinct oscillatory codes of retention and manipulation of verbal working memory

Pavlov, Y. G.; Kotchoubey, B.

10.1101/2021.03.13.435253 — neuroscience — Posted on 2021-03-13

2855 Optimized structure of monoubiquitinated FANCD2 (human) at Lys 561: a theoretical approach

Mukhopadhyay, S.; Mondal, S.; Reddy, S.

10.1101/2021.03.12.435201 — bioinformatics — Posted on 2021-03-13

2856 Persistence of SARS-CoV-2 virus and viral RNA on hydrophobic and hydrophilic surfaces and investigating contamination concentration

Paton, S. E.; Spencer, A.; Garratt, I.; Thompson, K.-A.; Dinesh, I.; AranegaBou, P.; Stevenson, D.; Clark, S. O.; Dunning, J.; Bennett, A. M.; Pottage, T.

10.1101/2021.03.11.435056 — microbiology — Posted on 2021-03-13

2857 A potential SARS-CoV-2 variant of interest (VOI) harboring mutation E484K in the Spike protein was identified within lineage B.1.1.33 circulating in Brazil

Resende, P. C.; Graf, T.; Paixao, A. C. D.; Appolinario, L.; Lopes, R. S.; Mendonca, A. C. F.; da Rocha, A. S. B.; Motta, F. C.; Neto, L. G. L.; Khouri, R.; de Oliveira, C. I.; Santos-Muccillo, P.; Bezerra, J. F.; Teixeira, D. L. F.; Riediger, I.; Debur, M. C.; Ribeiro-Rodrigues, R.; Leite, A. B.; do Santos, C. A.; Gregianini, T. S.; Fernandes, S. B.; Bernardes, A. F. L.; Cavalcanti, A. C.; Miyajima, F.; Sachhi, C.; Mattos, T.; da Costa, C. F.; Delatorre, E.; Wallau, G. L.; Naveca, F. G.; Bello, G.; Siqueira, M. M.

10.1101/2021.03.12.434969 — microbiology — Posted on 2021-03-13

2858 Radiation Threats to Humans in Space and an alternative approach with Probiotics

Diken, D.; Kaur, H.; Brodsky, E.; Mazumder, M.

10.1101/2021.03.12.435153 — microbiology — Posted on 2021-03-13

2859 Rare transmission of commensal and pathogenic bacteria in the gut microbiome of hospitalized adults

Siranosian, B. A.; Brooks, E.; Andermann, T.; Rezvani, A. R.; Banaei, N.; Tang, H.; Bhatt, A. S.

10.1101/2021.03.12.435204 — microbiology — Posted on 2021-03-13

2860 Yersinia pestis lipopolysaccharide remodeling confers resistance to a Xenopsylla cheopis cecropin

Mathew, B.; Aoyagi, K. L.; Fisher, M. A.

10.1101/2021.03.12.435208 — microbiology — Posted on 2021-03-13

2861 A robust voice-selective response in the human brain as revealed by electrophysiological recordings and fast periodic auditory stimulation

Barbero, F. M.; Calce, R. P.; Talwar, S.; Rossion, B.; Collignon, O.

10.1101/2021.03.13.435142 — neuroscience — Posted on 2021-03-13

2862 MicroMator: Open and Flexible Software for Reactive Microscopy

Fox, Z. R.; Fletcher, S.; Fraisse, A.; Aditya, C.; Sosa-Carrillo, S.; Gilles, S.; Bertaux, F.; Ruess, J.; Batt, G.

10.1101/2021.03.12.435206 — systems biology — Posted on 2021-03-13

2863 How a sticky fluid facilitates prey retention in a carnivorous pitcher plant (Nepenthes rafflesiana)

Kang, V.; Isermann, H.; Sharma, S.; Wilson, D. I.; Federle, W.

10.1101/2021.03.13.434712 — plant biology — Posted on 2021-03-13

2864 Good host - bad host: molecular and evolutionary basis for survival, its failure, and virulence factors of the zoonotic nematode Anisakis pegreffii

Trumbic, Z.; Hrabar, J.; Palevich, N.; Carbone, V.; Mladineo, I.

10.1101/2021.03.12.435207 — molecular biology — Posted on 2021-03-13

2865 Differential regulation of mRNA fate by the human Ccr4-Not complex is driven by CDS composition and mRNA localisation

Gillen, S. L.; Hodge, K.; Zanivan, S.; Bushell, M.; Wilczynska, A.

10.1101/2021.03.13.435226 — molecular biology — Posted on 2021-03-13

2866 What makes our lungs look red?

Huang, S.; Lopez, C.

10.1101/2021.03.13.435224 — cell biology — Posted on 2021-03-13

2867 New SARS-CoV-2 lineages could evade CD8+ T-cells response

Pretti, M. A. M.; Galvani, R. G.; Farias, A. S.; Boroni, M.

10.1101/2021.03.09.434584 — immunology — Posted on 2021-03-13

2868 Environmental, structural and taxonomic diversity factors drive aboveground carbon stocks in a semi-deciduous tropical rainforest strata in Cameroon

ZEKENG, J. C.; van der Sande, M. T.; Fobane, J. L.; Sebego, R.; Mphinyane, W. N.; Ebanga, P. A.; MBOLO, M. M. A.

10.1101/2021.03.12.435155 — ecology — Posted on 2021-03-13

2869 Neuronal mechanisms of novelty seeking

Ogasawara, T.; Sogukpinar, F.; Zhang, K.; Feng, Y.-Y.; Pai, J.; Jezzini, A.; Monosov, I. E.

10.1101/2021.03.12.435019 — neuroscience — Posted on 2021-03-13

2870 Intra-epithelial non-canonical Activin A signalling safeguards prostate progenitor quiescence

Cambuli, F.; Foletto, V.; Alaimo, A.; De Felice, D.; Gandolfi, F.; Palumbieri, M. D.; Zaffagni, M.; Genovesi, S.; Lorenzoni, M.; Celotti, M.; Bertossio, E.; Mazzero, G.; Bertossi, A.; Bisio, A.; Berardinelli, F.; Antoccia, A.; Gaspari, M.; Barbareschi, M.; Fiorentino, M.; Shen, M. M.; Loda, M.; Romanel, A.; Lunardi, A.

10.1101/2021.03.05.433921 — cancer biology — Posted on 2021-03-13

2871 α-Helical peptidic scaffolds to target α-synuclein pathogenic species with high affinity and selectivity.

Santos, J.; Gracia, P.; Navarro, S.; Pena-Diaz, S.; Pujols, J.; Cremades, N.; Pallares, I.; Ventura, S.

10.1101/2021.03.12.435074 — biophysics — Posted on 2021-03-13

2872 Massively parallel reporter perturbation assay uncovers temporal regulatory architecture during neural differentiation

Kreimer, A.; Ashuach, T.; Inoue, F.; Khodaverdian, A.; Yosef, N.; Ahituv, N.

10.1101/2021.03.12.435197 — genomics — Posted on 2021-03-12

2873 Progressive and predictive markers of disease evolution: platelet transcriptome in chronic myeloproliferative neoplasms

Shen, Z.; Du, W.; Perkins, C.; Fechter, L.; Natu, V.; Maecker, H.; Rowley, J.; Gotlib, J.; Zehnder, J.; Krishnan, A.

10.1101/2021.03.12.435190 — genomics — Posted on 2021-03-12

2874 A wild-derived antimutator drives germline mutation spectrum differences in a genetically diverse murine family

Sasani, T. A.; Ashbrook, D. G.; Lu, L.; Palmer, A. A.; Williams, R. W.; Pritchard, J. K.; Harris, K.

10.1101/2021.03.12.435196 — genetics — Posted on 2021-03-13

2875 Endomitosis controls tissue-specific gene expression during development

van Rijnberk, L. M.; van der Palen, R. L.; Schild, E. S.; Korswagen, H. C.; Galli, M.

10.1101/2021.03.12.435137 — cell biology — Posted on 2021-03-13

2876 Super-human cell death detection with biomarker-optimized neural networks

Linsley, J. W.; Linsley, D.; Lamstein, J.; Ryan, G.; Shah, K.; Castello, N. A.; Oza, V.; Kalra, J.; Wang, S.; Tokuno, Z.; Javaherian, A.; Serre, T.; Finkbeiner, S.

10.1101/2020.08.04.237032 — cell biology — Posted on 2021-03-13

2877 Ca2+-activated sphingomyelin scrambling and turnover mediate ESCRT-independent lysosomal repair

Niekamp, P.; Sokoya, T.; Vittadello, L.; Deng, Y.; Kim, Y.; Hilderink, A.; Imlau, M.; Clarke, C. J.; Burd, C. G.; Holthuis, J. C. M.

10.1101/2021.03.12.435146 — cell biology — Posted on 2021-03-13

2878 Context-dependent miR-21 regulation of TLR7-mediated autoimmune and foreign antigen driven antibody-forming cell and germinal center responses

Schell, S.; Bricker, K. N.; Fike, A. J.; Chodisetti, S. B.; Domeier, P. P.; Choi, N. M.; Fasnacht, M. J.; Luckenbill, S. A.; Ziegler, S. F.; Rahman, Z. S. M.

10.1101/2021.03.12.435182 — immunology — Posted on 2021-03-13

2879 Sustained antibody response to ZIKV infection induced by NS1 protein is accompanied by the progressive appearance of autoreactive antibodies and cross-reactive B cell clones.

Cavazzoni, C. B.; Bozza, V. B.; Tostes, L.; Maia, B.; Mesin, L.; Schiepers, A.; Ersching, J.; Neris, R. L.; Conde, J. N.; Coleho, D. R.; Conde, L.; Paula-Neto, H. A.; Lima, T. M.; Alvim, R. G. F.; Castilho, L. R.; Mohana-Borges, R.; Assuncao-Miranda, I.; Nobrega, A.; Victora, G. D.; Vale, A. M.

10.1101/2020.12.24.423863 — immunology — Posted on 2021-03-13

2880 Synaptotagmin rings as high sensitivity regulators of synaptic vesicle docking and fusion

Zhu, J.; McDargh, Z. A.; Li, F.; Krishnakumar, S.; Rothman, J. E.; O'Shaughnessy, B.

10.1101/2021.03.12.435193 — neuroscience — Posted on 2021-03-13

2881 Hippocampal and thalamic afferents form distinct synaptic microcircuits in the mouse frontal cortex

Graham, K.; Spruston, N.; Bloss, E. B.

10.1101/2021.03.12.435140 — neuroscience — Posted on 2021-03-13

2882 Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration

Linsley, J. W.; Shah, K.; Castello, N.; Chan, M.; Haddad, D.; Mancini, J.; Oza, V.; Wang, S.; Javaherian, A.; Kokel, D.; Finkbeiner, S.

10.1101/726588 — neuroscience — Posted on 2021-03-13

2883 Electro-Metabolic Sensing Through Capillary ATP-Sensitive K+ Channels and Adenosine to Control Cerebral Blood Flow

Sancho, M.; Klug, N. R.; Mughal, A.; Heppner, T. J.; Hill-Eubanks, D.; Nelson, M. T.

10.1101/2021.03.12.435152 — neuroscience — Posted on 2021-03-13

2884 Multimodal image fusion via deep generative models

Dimitri, G. M.; Spasov, S.; Duggento, A.; Passamonti, L.; Lio, P.; Toschi, N.

10.1101/2021.03.08.434427 — neuroscience — Posted on 2021-03-13

2885 Neural Networks for parameter estimation in microstructural MRI: a study with a high-dimensional diffusion-relaxation model of white matter microstructure

de Almeida Martins, J. P.; Nilsson, M.; Lampinen, B.; Palombo, M.; While, P. T.; Westin, C.-F.; Szczepankiewicz, F.

10.1101/2021.03.12.435163 — neuroscience — Posted on 2021-03-13

2886 Consensus clustering for Bayesian mixture models

Coleman, S. D.; Kirk, P. D.; Wallace, C.

10.1101/2020.12.17.423244 — systems biology — Posted on 2021-03-13

2887 Molecular Response to PARP1 Inhibition in Ovarian Cancer Cells as Determined by Mass Spectrometry Based Proteomics

Franz, A.; Coscia, F.; Charaoui, L.; Shen, C.; Mann, M.; Sander, C.

10.1101/2021.03.12.435005 — cancer biology — Posted on 2021-03-13

2888 Large-scale design and refinement of stable proteins using sequence-only models

Singer, J. M.; Novotney, S.; Strickland, D.; Haddox, H. K.; Leiby, N.; Rocklin, G. J.; Chow, C. M.; Roy, A.; Bera, A. K.; Motta, F. C.; Cao, L.; Strauch, E.-M.; Chidyausiku, T. M.; Ford, A.; Ho, E.; Mackenzie, C. O.; Eramian, H.; DiMaio, F.; Grigoryan, G.; Vaughn, M.; Stewart, L. J.; Baker, D.; Klavins, E.

10.1101/2021.03.12.435185 — biophysics — Posted on 2021-03-12

2889 Thermal stimulation neurophysiology of pressure phosphenes

Kholmanskiy, A.; Konyukhova, E.; Minakhin, A.

10.1101/2021.03.12.435166 — biophysics — Posted on 2021-03-13

2890 VCFcontam: A Machine Learning Approach to Estimate Cross-Sample Contamination from Variant Call Data

McCartney-Melstad, E.; Bi, K.; Han, J.; Foo, C. K.

10.1101/2021.03.12.435007 — bioinformatics — Posted on 2021-03-12

2891 An Off-the-Shelf Bioadhesive Patch for Sutureless Repair of Gastrointestinal Defects

Wu, J.; Yuk, H.; Sarrafian, T. L.; Guo, C.; Griffiths, L. G.; Nabzdyk, C. S.; Zhao, X.

10.1101/2021.03.12.435203 — bioengineering — Posted on 2021-03-12

2892 A Fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis.

Gupta, P.; Thomas, S. E.; Cory-Wright, J.; Sebastián-Pérez, V.; Burgess, A.; Cattermole, E.; Meghir, C.; Abell, C.; Coyne, A. G.; Jacobs, W. R.; Blundell, T. L.; Tiwari, S.; Mendes, V.

10.1101/2021.03.12.435067 — biochemistry — Posted on 2021-03-12

2893 Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance

Tsai, K.; Stojkovic, V.; Noda-Garcia, L.; Young, I. D.; Myasnikov, A. G.; Kleinman, J.; Palla, A.; Floor, S. N.; Frost, A.; Fraser, J. S.; Tawfik, D. S.; Galonic Fujimori, D.

10.1101/2021.03.12.435202 — biochemistry — Posted on 2021-03-13

2894 Urban fox squirrels exhibit tolerance to humans but respond to stimuli from natural predators

Kittendorf, A.; Dantzer, B.

10.1101/2020.12.18.423423 — animal behavior and cognition — Posted on 2021-03-12

2895 Intriguing effects of selection intensity on the evolution of prosocial behaviors

McAvoy, A.; Rao, A.; Hauert, C.

10.1101/2021.03.12.435199 — evolutionary biology — Posted on 2021-03-13

2896 An extended DNA-free intranuclear compartment organizes centrosomal microtubules in Plasmodium falciparum

Simon, C. S.; Voss, Y.; Funaya, C.; Machado, M.; Penning, A.; Klaschka, D.; Cyrklaff, M.; Kim, J.; Ganter, M.; Guizetti, J.

10.1101/2021.03.12.435157 — cell biology — Posted on 2021-03-12

2897 A novel juxtamembrane basolateral targeting motif regulates TGF-β receptor signaling in Drosophila

Peterson, A. J.; Murphy, S. J.; Mundt, M. G.; Shimell, M.; Leof, E. B.; O'Connor, M. B.

10.1101/2020.10.05.327056 — cell biology — Posted on 2021-03-13

2898 DNA origami patterning of synthetic T cell receptors reveals spatial control of the sensitivity and kinetics of signal activation

Dong, R.; Aksel, T.; Chan, W.; Germain, R. N.; Vale, R. D.; Douglas, S. M.

10.1101/2021.03.12.434905 — cell biology — Posted on 2021-03-13

2899 Cdk8 directly regulates glycolysis via phosphorylation of Gcr2

Aristizabal, M. J.; O'Duibhir, E.; de Jonge, W.; Dever, K.; Hawe, N.; Koerkamp, M. G.; Brok, M.; van Leenen, D.; Lijnzaad, P.; Kobor, M. S.; Holstege, F. C. P.; Sadowski, I.

10.1101/2021.03.12.435012 — molecular biology — Posted on 2021-03-12

2900 Systems analysis of gut microbiome influence on metabolic disease in HIV and high-risk populations

Armstrong, A. J.; Quinn, K.; Li, S. X.; Schneider, J. M.; Nusbacher, N. M.; Doenges, K. A.; Fiorillo, S.; Marden, T. J.; Higgins, J.; Reisdorph, N.; Campbell, T. B.; Palmer, B. E.; Lozupone, C. A.

10.1101/2021.03.12.435118 — microbiology — Posted on 2021-03-12

2901 Antimalarials in mosquitoes overcome Anopheles and Plasmodium resistance to malaria control strategies

Paton, D. G.; Probst, A. S.; Ma, E.; Adams, K. L.; Shaw, W. R.; Singh, N.; Bopp, S.; Volkman, S. K.; Hien, D. F. S.; Yerbanga, S. R.; Lefevre, T.; Diabate, A.; Dabire, R. K.; Wirth, D.; Catteruccia, F.

10.1101/2021.03.12.435188 — microbiology — Posted on 2021-03-12

2902 Natural genetic variation drives microbiome selection in the Caenorhabditis elegans gut

Zhang, F.; Weckhorst, J. L.; Assie, A.; Hosea, C.; Ayoub, C. A.; Khodakova, A.; Cabrera, M. L.; Vidal, D.; Felix, M.-A.; Samuel, B. S.

10.1101/2021.03.12.435148 — microbiology — Posted on 2021-03-13

2903 Brucella ovis cysteine biosynthesis contributes to peroxide stress survival and fitness in the intracellular niche

Varesio, L.; Fiebig, A.; Crosson, S.

10.1101/2020.12.22.424080 — microbiology — Posted on 2021-03-13

2904 Cell-intrinsic functions of the transcription factor Bhlhe40 in activated B cells and T follicular helper cells restrain the germinal center reaction and prevent lymphomagenesis

Rauschmeier, R.; Reinhardt, A.; Gustafsson, C.; Glaros, V.; Artemov, A. V.; Taneja, R.; Mansson, R.; Busslinger, M.; Kreslavsky, T.

10.1101/2021.03.12.435122 — immunology — Posted on 2021-03-12

2905 Individualized event structure drives individual differences in whole-brain functional connectivity

Betzel, R.; Cutts, S.; Greenwell, S.; Sporns, O.

10.1101/2021.03.12.435168 — neuroscience — Posted on 2021-03-12

2906 Face processing of social cognition in patients with first episode psychosis: Its deficits and association with the right subcallosal anterior cingulate cortex

Narita, Z.; Kuga, H.; Piancharoen, P.; Faria, A.; Mihaljevic, M.; Longo, L.; Etyemez, S.; Namkung, H.; Coughlin, J.; Nestadt, G.; Nucifora, F.; Sedlak, T.; Schaub, R.; Crawford, J.; Schretlen, D.; Ishizuka, K.; Miyata, J.; Yang, K.; Sawa, A.

10.1101/2021.03.12.435039 — neuroscience — Posted on 2021-03-12

2907 Altered cortico-subcortical network after adolescent alcohol exposure mediates behavioral deficits in flexible decision-making

Gomez-A, A.; Dannenhoffer, C. A.; Elton, A.; Lee, S.; Ban, W.; Shih, Y.-Y. I.; Boettiger, C. A.; Robinson, D. L.

10.1101/2021.03.12.435040 — neuroscience — Posted on 2021-03-12

2908 GWAS-associated variants, non-genetic factors and transient transcriptome in Multiple Sclerosis etiopathogenesis: a colocalization analysis

Umeton, R.; Bellucci, G.; Bigi, R.; Romano, S.; Buscarinu, M. C.; Renie', R.; Rinaldi, V.; Pizzolato Umeton, R.; Morena, E.; Romano, C.; Mechelli, R.; Salvetti, M.; Ristori, G.

10.1101/2021.03.12.434773 — neuroscience — Posted on 2021-03-12

2909 In vitro neuronal networks show bidirectional axonal conduction with antidromic action potentials effectively depolarizing the soma

Mateus, J.; Lopes, C.; Aroso, M.; Costa, A.; Geros, A.; Pereira, A.; Meneses, J.; Faria, P.; Neto, E.; Lamghari, M.; Sousa, M.; Aguiar, P.

10.1101/2021.03.07.434278 — neuroscience — Posted on 2021-03-12

2910 The Kappa Opioid Receptor is required for some intermittent alcohol drinking induced changes in stress and threat responding in male C57BL/6J mice

Hwa, L. S.; Bowling, M. E.; Calloway, R.; kash, t.

10.1101/2020.09.23.310284 — neuroscience — Posted on 2021-03-12

2911 Embryo development in Carica papaya Linn

Benavides-Acevedo, M.; Bolanos-Villegas, P.

10.1101/2021.03.11.434975 — plant biology — Posted on 2021-03-12

2912 Deep learning from multiple experts improves identification of amyloid neuropathologies

Wong, D. R.; Tang, Z.; Mew, N. C.; Das, S.; Athey, J.; McAleese, K. E.; Kofler, J. K.; Flanagan, M. E.; Borys, E.; White, C. L.; Butte, A. J.; Dugger, B. N.; Keiser, M. J.

10.1101/2021.03.12.435050 — pathology — Posted on 2021-03-12

2913 Injury caused by alcoholic cardiomyopathy in spontaneous ethanol drinking rats

Camargo, V. M. B.; Fioravante, V. C.; Pinheiro, P. F. F.; Martinez, F. E.

10.1101/2021.03.12.435159 — pathology — Posted on 2021-03-12

2914 Cell Communication Network factor 4 promotes tumor-induced immunosuppression in melanoma

Fernandez, A.; Deng, W.; McLaughlin, S. L.; Pirkey, A. C.; Rellick, S.; Klinke, D. J.

10.1101/2021.02.23.432584 — cancer biology — Posted on 2021-03-12

2915 Ensemble Switching Unveils a Kinetic Rheostat Mechanism of the Eukaryotic Thiamine PyrophosphateRiboswitch

Ma, J.; Saikia, N.; Godar, S.; Hamilton, G. L.; Ding, F.; Alper, J.; Sanabria, H.

10.1101/2021.03.12.434875 — biophysics — Posted on 2021-03-12

2916 TMEM106B in humans and Vac7 and Tag1 in yeast are predicted to be lipid transfer proteins

Levine, T. P.

10.1101/2021.03.12.435176 — bioinformatics — Posted on 2021-03-12

2917 Phase and amplitude correlations change with disease progression in idiopathic Rapid eye-movement sleep behavior disorder patients

Roascio, M.; Canessa, A.; Tro', R. D.; Mattioli, P.; Fama', F.; Giorgetti, L.; Girtler, N.; Orso, B.; Morbelli, S.; Nobili, F. M.; Arnaldi, D.; Arnulfo, G.

10.1101/2021.03.12.435081 — bioengineering — Posted on 2021-03-12

2918 A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing

Fan, H.; Guo, Y.; Tsai, Y.-H.; Storey, A.; Kim, A.; Gong, W.; Edmondson, R.; Mackintosh, S.; Li, H.; Byrum, S.; Tackett, A.; Cai, L.; Wang, G. G.

10.1101/2021.03.11.435004 — biochemistry — Posted on 2021-03-12

2919 Drug-bound and -free outward-facing structures of a multidrug ABC exporter point to a swing mechanism

Chaptal, v.; Zampieri, V.; Wiseman, B.; Orelle, C.; Martin, J.; Nguyen, K.-A.; Magnard, S.; Gobet, A.; Di cesare, M.; Javed, W.; Kilburg, A.; Peuchmaur, M.; Marcoux, J.; Hogbom, M.; Jault, J.-M.; Boumendjel, A.; Falson, P. G.

10.1101/2021.03.12.435132 — biochemistry — Posted on 2021-03-12

2920 DNA methylation is not a driver of gene expression reprogramming in young honey bee workers

Cardoso Junior, C.; Yagound, B.; Ronai, I.; Remnant, E. J.; Hartfelder, K.; Oldroyd, B.

10.1101/2021.03.12.435154 — genomics — Posted on 2021-03-12

2921 Mitochondrial Phenotypes Distinguish Pathogenic MFN2 Mutations by Pooled Functional Genomics Screen

Yenkin, A. L.; Bramley, J. C.; Waligorski, J. E.; Kremitzki, C. L.; Liebeskind, M. J.; Xu, X. E.; Vakaki, M. A.; Chandrasekaran, V.; Mitra, R. D.; Milbrandt, J. D.; Buchser, W. J.

10.1101/2021.03.12.434746 — genomics — Posted on 2021-03-12

2922 A single synonymous nucleotide change impacts the male-killing phenotype of prophage WO gene wmk

Perlmutter, J.; Meyers, J. E.; Bordenstein, S. R.

10.1101/2021.03.11.434916 — genomics — Posted on 2021-03-12

2923 High-resolution simulations of chromatin folding at genomic rearrangements in malignant B-cells provide mechanistic insights on proto-oncogene deregulation

Rico, D.; Kent, D.; Mikulasova, A.; Karataraki, N.; Walker, B. A.; Javierre, B. M.; Russell, L. J.; Brackley, C. A.

10.1101/2021.03.12.434963 — genomics — Posted on 2021-03-12

2924 The dynamic effect of regulatory genetic variation on the in vivo ER stress transcriptional response

Russell, N. D.; Chow, C. Y.

10.1101/2021.03.12.435172 — genetics — Posted on 2021-03-12

2925 Wrack enhancement of post-hurricane vegetation and geomorphological recovery in a coastal dune

Joyce, M. A.; Griffin, J. N.; Crotty, S. M.; Angelini, C.; Cordero, O.; Ortals, C.; DeBattisti, D.

10.1101/2021.03.12.435051 — ecology — Posted on 2021-03-12

2926 Reconstructing human early embryogenesis in vitro with pluripotent stem cells

Zernicka-Goetz, M.; Sozen, B.; Jorgensen, V.; Cui, T.; Zhu, M.

10.1101/2021.03.12.435175 — developmental biology — Posted on 2021-03-12

2927 A role for a micron-scale supramolecular myosin array in adherens junction cytoskeletal assembly

Yu-Kemp, H.-C.; Szymanski, R.; Gadda, N.; Lillich, M.; Peifer, M.

10.1101/2021.03.12.435158 — cell biology — Posted on 2021-03-12

2928 Measuring context-dependent memory in rodents: a systematic review and meta-analysis of important variables in the object-in-context task.

Sep, M.; Vellinga, M.; Sarabdjitsingh, R. A.; Joëls, M.

10.1101/2021.03.12.435070 — neuroscience — Posted on 2021-03-12

2929 Behavioral rebound following isolation of attention

Edwards, G.; Berestova, A.; Battelli, L.

10.1101/2020.12.17.423241 — neuroscience — Posted on 2021-03-12

2930 Rediscovering the musician's brain: a systematic review and meta-analysis

Criscuolo, A.; Pando-Naude, V.; Bonetti, L.; Vuust, P.; Brattico, E.

10.1101/2021.03.12.434473 — neuroscience — Posted on 2021-03-12

2931 Comparison of domain adaptation techniques for white matter hyperintensity segmentation in brain MR images

Sundaresan, V.; Zamboni, G.; Dinsdale, N. K.; Rothwell, P. M.; Griffanti, L.; Jenkinson, M.

10.1101/2021.03.12.435171 — neuroscience — Posted on 2021-03-12

2932 Primed to Die: An Investigation of the Genetic Mechanisms Underlying Noise-Induced Hearing Loss and Cochlear Damage in Homozygous Foxo3-knockout Mice

Beaulac, H. J.; Gilels, F.; Zhang, J.; Jeoung, S.; White, P.

10.1101/2021.03.12.435183 — neuroscience — Posted on 2021-03-12

2933 Experience-related remapping of temporal encoding by striatal ensembles.

Bruce, R.; Weber, M.; Volkman, R.; Oya, M.; Emmons, E.; Kim, Y.; Narayanan, N.

10.1101/2021.03.12.435177 — neuroscience — Posted on 2021-03-12

2934 In-land long-term culture of colonial ascidians

Wawrzyniak, M. K.; Matas Serrato, L. A.; Blanchoud, S.

10.1101/2021.01.31.429038 — zoology — Posted on 2021-03-12

2935 Flexible analysis of animal behavior via time-resolved manifold embedding

York, R. A.; Carreira-Rosario, A.; Giocomo, L. M.; Clandinin, T. R.

10.1101/2020.09.30.321406 — animal behavior and cognition — Posted on 2021-03-12

2936 Crosstalk in oxygen homeostasis networks: SKN-1/NRF inhibits the HIF-1 hypoxia-inducible factor in Caenorhabditis elegans

Feng, D.; Zhai, Z.; Shao, Z.; Zhang, Y.; Powell-Coffman, J. A.

10.1101/2021.03.12.435071 — genetics — Posted on 2021-03-12

2937 A dynamical system model for predicting gene expression from the epigenome

Brunner, J. D.; Kim, J.; Downing, T. L.; Mjolsness, E.; Kober, K. M.

10.1101/2020.08.03.234740 — systems biology — Posted on 2021-03-12

2938 Data-driven learning how oncogenic gene expression locally alters heterocellular networks

Klinke, D. J.; Fernandez, A.; Deng, W.; Latifizadeh, H.; Pirkey, A. C.

10.1101/2020.05.04.077107 — systems biology — Posted on 2021-03-12

2939 Data-driven causal analysis of observational time series in ecology

Yuan, A. E.; Shou, W.

10.1101/2020.08.03.233692 — bioinformatics — Posted on 2021-03-12

2940 A genetic screen identifies new steps in oocyte maturation that enhance proteostasis in the immortal germ lineage

Samaddar, M.; Goudeau, J.; Sanchez, M.; Hall, D. H.; Bohnert, K. A.; Ingaramo, M.; Kenyon, C.

10.1101/2020.08.31.276006 — cell biology — Posted on 2021-03-12

2941 Hyperrealistic neural decoding: Reconstructing faces from fMRI activations via the GAN latent space

Dado, T.; Gucluturk, Y.; Ambrogioni, L.; Ras, G.; Bosch, S. E.; van Gerven, M.; Guclu, U.

10.1101/2020.07.01.168849 — neuroscience — Posted on 2021-03-12

2942 Zetaproteobacteria pan-genome reveals candidate gene cluster for twisted stalk biosynthesis and export

Koeksoy, E.; Bezuidt, O. M.; Emerson, D.; Chan, C. S.; Bayer, T.

10.1101/2021.03.12.435129 — microbiology — Posted on 2021-03-12

2943 Multi-compartment analysis of the complex gradient-echo signal quantifies myelin breakdown in premanifest Huntington's disease

Casella, C.; Kleban, E.; Rosser, A. E.; Coulthard, E.; Rickards, H.; Fasano, F.; Metzler-baddeley, C.; Jones, D. K.

10.1101/2021.03.12.435119 — neuroscience — Posted on 2021-03-12

2944 Performance comparison and in-silico harmonisation of commercial platforms for DNA methylome analysis by targeted bisulfite sequencing

Tanic, M.; Moghul, I.; Rodney, S.; Dhami, P.; Vaikkinen, H.; Ambrose, J.; Barrett, J.; Feber, A.; Beck, S.

10.1101/2021.03.12.435105 — genomics — Posted on 2021-03-12

2945 Joint inference of adaptive and demographic history from temporal population genomic data

Pavinato, V. A. C.; De Mita, S.; Marin, J.-M.; de Navascues, M.

10.1101/2021.03.12.435133 — evolutionary biology — Posted on 2021-03-12

2946 The geometry of face memory

She, L.; Benna, M. K.; Shi, Y.; Fusi, S.; Tsao, D. Y.

10.1101/2021.03.12.435023 — neuroscience — Posted on 2021-03-12

2947 Learning accurate path integration in a ring attractor model of the head direction system

Vafidis, P.; Owald, D.; D'Albis, T.; Kempter, R.

10.1101/2021.03.12.435035 — neuroscience — Posted on 2021-03-12

2948 Associations Between Vocal Emotion Recognition and Socio-emotional Adjustment in Children

Neves, L.; Martins, M.; Correia, A. I.; Castro, S. L.; Lima, C.

10.1101/2021.03.12.435099 — neuroscience — Posted on 2021-03-12

2949 Next-generation biocomputing: mimicking artificial neural network with genetic circuits

Seak, L. C. U.; Lo, O. L. I.; Suen, W. C.-W.; Wu, M.-T.

10.1101/2021.03.12.435120 — synthetic biology — Posted on 2021-03-12

2950 Paper-and-pencil questionnaires analysis: a new automated technique to reduce analysis time and errors.

Chabert, C.; Collado, A.; Cheval, B.; Hue, O.

10.1101/2021.03.12.435109 — scientific communication and education — Posted on 2021-03-12

2951 An ancient route towards salicylic acid and its implications for the perpetual Trichormus-Azolla symbiosis

de Vries, S.; Herrfurth, C.; Li, F.-W.; Feussner, I.; de Vries, J.

10.1101/2021.03.12.435107 — plant biology — Posted on 2021-03-12

2952 Kidney-Specific WNK1 Amplifies NCC Responsiveness to Potassium Imbalance

Boyd-Shiwarski, C. R.; Beacham, R. T.; Griffiths, S. E.; Shiwarski, D. J.; Knoell, S. A.; Nkashama, L. J.; Querry, K. E.; Marciszyn, A. L.; Huang, C.-L.; Stocker, S. D.; Subramanya, A. R.

10.1101/2021.03.12.435046 — physiology — Posted on 2021-03-12

2953 Can offsetting the energetic cost of hibernation restore an active season phenotype in grizzly bears (Ursus arctos horribilis)?

Jansen, H. T.; Evans Hutzenbiler, B. D.; Hapner, H. R.; McPhee, M. L.; Carnahan, A. M.; Kelley, J. L.; Saxton, M. W.; Robbins, C. T.

10.1101/2021.03.12.435162 — physiology — Posted on 2021-03-12

2954 SGI: Automatic clinical subgroup identification in omics datasets

Buyukozkan, M.; Krumsiek, J.

10.1101/2021.03.12.435108 — bioinformatics — Posted on 2021-03-12

2955 SweepCluster: A SNP clustering tool for detecting gene-specific sweeps in prokaryotes

Qiu, J.; Zhou, Q.; Ye, W.; Chen, Q.; Bao, Y.-J.

10.1101/2021.03.12.435060 — bioinformatics — Posted on 2021-03-12

2956 DNA methylome-based validation of induced sputum as an effective protocol to study lung immunity: construction of a classifier of pulmonary cell types

Das, J.; Idh, N.; Paues, J.; Sikkeland, L. I. B.; Lerm, M.

10.1101/2021.03.12.435086 — genomics — Posted on 2021-03-12

2957 Whole Genome Assembly and Annotation of Northern Wild Rice, Zizania palustris L., Supports a Whole Genome Duplication in the Zizania Genus

Haas, M. W.; Kono, T. J. Y.; Macchietto, M.; Millas, R.; McGilp, L.; Shao, M.; Duquette, J.; Hirsch, C.; Kimball, J. A.

10.1101/2021.03.12.435103 — genomics — Posted on 2021-03-12

2958 Management programs as a key factor for genetic conservation of small populations : The case of French local chicken breeds

Restoux, G.; Rognon, X.; Vieaud, A.; Guemene, D.; Petitjean, F.; Rouger, R.; Brard-Fudulea, S.; Lubac, S.; Chiron, G.; Tixier-Boichard, M.

10.1101/2021.03.12.435064 — genetics — Posted on 2021-03-12

2959 Life-history evolution of class-structured populations in fluctuating environments

Lion, S.; Gandon, S.

10.1101/2021.03.12.435065 — evolutionary biology — Posted on 2021-03-12

2960 Genomic epidemiology of Mycobacterium bovis infection in sympatric badger and cattle populations in Northern Ireland.

Akhmetova, A.; Guerrero, J.; McAdam, P.; Salvador, L. C. M.; Crispell, J.; Lavery, J.; Presho, E.; Kao, R. R.; Biek, R.; Menzies, F.; Trimble, N.; Harwood, R.; Pepler, T.; Oravcova, K.; Graham, J.; Skuce, R. A.; du Plessis, L. R.; Thompson, S.; Wright, L.; Byrne, A. W.; Allen, A. R.

10.1101/2021.03.12.435101 — evolutionary biology — Posted on 2021-03-12

2961 Social selection and the evolution of maladaptation

McGlothlin, J. W.; Fisher, D. N.

10.1101/2021.03.12.435141 — evolutionary biology — Posted on 2021-03-12

2962 Niche specificity, polygeny, and pleiotropy in herbivorous insects

Hardy, N. B.; Forister, M.

10.1101/2021.03.12.435098 — evolutionary biology — Posted on 2021-03-12

2963 The GT factor ZmGT-3b mediates growth-defense tradeoff by regulating photosynthesis and defense response

Ye, J.; Zhang, Q.-q.; E, L.; Dai, W.; Xu, M.-l.

10.1101/2021.03.12.435151 — molecular biology — Posted on 2021-03-12

2964 Niche partitioning facilitates coexistence of closely related gut bacteria

Brochet, S.; Quinn, A.; Mars, R. A. T.; Neuschwander, N.; Sauer, U.; Engel, P.

10.1101/2021.03.12.434400 — microbiology — Posted on 2021-03-12

2965 Tree phyllospheres are a habitat for diverse populations of CO-oxidising bacteria

Palmer, J. L.; Hilton, S.; Picot, E.; Bending, G. D.; Schaefer, H.

10.1101/2021.03.12.435102 — microbiology — Posted on 2021-03-12

2966 Exiguobacterium Sp. HA2, isolated from the Ilam Mountains of Iran

Heidari, R.; Akbariqomi, M.; Tavoosidana, G.; Rigi, G.

10.1101/2021.03.12.435112 — microbiology — Posted on 2021-03-12

2967 Towards a More General Understanding of the Algorithmic Utility of Recurrent Connections

Larsen, B. W.; Druckmann, S.

10.1101/2021.03.12.435130 — neuroscience — Posted on 2021-03-12

2968 A metal ion orients mRNA to ensure accurate 2'-O ribosyl methylation of the first nucleotide of the SARS-CoV-2 genome

Viswanathan, T.; Misra, A.; Chan, S.-H.; Qi, S.; Dai, N.; Arya, S.; Martinez-Sobrido, L.; Gupta, Y. K.

10.1101/2021.03.12.435174 — biochemistry — Posted on 2021-03-12

2969 An Innovative antibody-based Plug-and-Play strategy for SARS-CoV-2

Tushir-Singh, J.; Shivange, G. N.; Gogoi, D.

10.1101/2021.03.11.434589 — biochemistry — Posted on 2021-03-12

2970 Discriminative feature of cells characterizes cell populations of interest by a small subset of genes

Fujii, T.; Maehara, K.; Fujita, M.; Ohkawa, Y.

10.1101/2021.03.12.435089 — bioinformatics — Posted on 2021-03-12

2971 Epigenetic clocks reveal a rejuvenation event during embryogenesis followed by aging

Kerepesi, C.; Zhang, B.; Lee, S.-G.; Trapp, A.; Gladyshev, V. N.

10.1101/2021.03.11.435028 — developmental biology — Posted on 2021-03-12

2972 The PPR domain of mitochondrial RNA polymerase is a ribonuclease required for mtDNA replication

Xu, H.

10.1101/2021.03.12.435139 — molecular biology — Posted on 2021-03-12

2973 Yeast proteins reversibly aggregate like amphiphilic molecules

Dasmeh, P.; Wagner, A.

10.1101/2021.03.12.435082 — molecular biology — Posted on 2021-03-12

2974 Immunoprofiling reveals novel mast cell receptors and a continuous nature of human lung mast cell heterogeneity

Rönnberg, E.; Zhong Hao Boey, D.; Ravindran, A.; Säfholm, J.; Orre, A.-C.; Al-Ameri, M.; Adner, M.; Dahlen, S.-E.; Dahlin, J. S.; Nilsson, G.

10.1101/2021.03.12.435093 — immunology — Posted on 2021-03-12

2975 TAPAS: an open-source software package for Translational Neuromodeling and Computational Psychiatry

Frässle, S.; Aponte, E. A.; Bollmann, S. A.; Brodersen, K. H.; Do, C. T.; Harrison, O. K.; Harrison, S. J.; Heinzle, J.; Iglesias, S.; Kasper, L.; Lomakina, E. I.; Mathys, C.; Müller-Schrader, M.; Pereira, I.; Petzschner, F. H.; Raman, S.; Schöbi, D.; Toussaint, B.; Weber, L. A.; Yao, Y.; Stephan, K. E.

10.1101/2021.03.12.435091 — neuroscience — Posted on 2021-03-12

2976 A specialist flea beetle manipulates and tolerates the activated chemical defense in its host plant

Sporer, T.; Koernig, J.; Wielsch, N.; Gebauer-Jung, S.; Reichelt, M.; Hupfer, Y.; Beran, F.

10.1101/2021.03.12.435088 — physiology — Posted on 2021-03-12

2977 Familial thyroid follicular cell carcinomas in a large number of Dutch German longhaired pointers

Yu, Y.; Krupa, A.; Keesler, R.; Grinwis, G. C. M.; Ruijsscher, M.; Groenen, M. A. M.; Crooijmans, R. P. M. A.

10.1101/2021.03.12.434920 — cancer biology — Posted on 2021-03-12

2978 Confronting false discoveries in single-cell differential expression

Squair, J. W.; Gautier, M.; Kathe, C.; Anderson, M. A.; James, N. D.; Hutson, T. H.; Hudelle, R.; Qaiser, T.; Matson, K. J. E.; Barraud, Q.; Levine, A. J.; La Manno, G.; Skinnider, M. A.; Courtine, G.

10.1101/2021.03.12.435024 — bioinformatics — Posted on 2021-03-12

2979 FlywheelTools: Data Curation and Manipulation on the Flywheel Platform

Tapera, T. M.; Cieslak, M.; Bertolero, M.; Adembimpe, A.; Aguirre, G. K.; Butler, E. R.; Cook, P. A.; Davila, D.; Elliot, M. A.; Linguiti, S.; Murtha, K.; Tackett, W.; Satterthwaite, T. D.

10.1101/2021.03.12.434998 — bioinformatics — Posted on 2021-03-12

2980 An ecological explanation for hyperallometric scaling of reproduction

Potter, T.; Felmy, A.

10.1101/2021.03.12.435090 — ecology — Posted on 2021-03-12

2981 Chimeric spike mRNA vaccines protect against sarbecovirus challenge in mice

Martinez, D. R.; Schaefer, A.; Leist, S. R.; De la Cruz, G.; West, A.; Atochina-Vasserman, E. N.; Parks, R.; Barr, M.; Li, D.; Yount, B.; Saunders, K. O.; Weissman, D.; Haynes, B.; Montgomery, S. A.; Baric, R. S.

10.1101/2021.03.11.434872 — microbiology — Posted on 2021-03-12

2982 Generation of fluorescent HCV pseudoparticles to study early viral entry events- involvement of Rab1a in HCV entry

Bhattacharjee, C.; Mukhopadhyay, A.

10.1101/2021.03.11.434898 — microbiology — Posted on 2021-03-12

2983 Loss of TCF-1 regulates the production of noncanonical Tregs in a prion-like manner

Harris, R.; Mammadli, M.; Karimi, M.

10.1101/2021.03.11.435008 — immunology — Posted on 2021-03-12

2984 Affinity selection in germinal centers: Cautionary tales and new opportunities

Faro, J.; Castro, M.

10.1101/2021.03.12.435085 — immunology — Posted on 2021-03-12

2985 Efficient high-resolution TMS mapping of the human motor cortex by nonlinear regression

Numssen, O.; Zier, A.-L.; Thielscher, A.; Hartwigsen, G.; Knosche, T.; Weise, K.

10.1101/2021.03.11.434996 — neuroscience — Posted on 2021-03-12

2986 Introspection confidence correlates with EEG decoding of self-generated thoughts and meta-awareness

Polychroni, N.; Herrojo Ruiz, M.; Terhune, D. B.

10.1101/2021.03.12.435068 — neuroscience — Posted on 2021-03-12

2987 Oligodendrocyte Precursor Cells Sculpt the Visual System by Regulating Axonal Remodeling

Xiao, Y.; Hoodless, L. J.; Petrucco, L.; Portugues, R.; Czopka, T.

10.1101/2021.03.11.434829 — neuroscience — Posted on 2021-03-12

2988 Mental health explains individual deviations from normative range in cognition-associated brain states

Zhang, W.; Vidaurre, D.; Bijsterbosch, J. D.

10.1101/2021.03.12.435017 — neuroscience — Posted on 2021-03-12

2989 The Sugar Porter gene family of Piriformospora indica: Nomenclature, Transcript Profiling and Characterization

Raj, S.; Kumar, M.; Singh, A. K.; Dua, M.; Johri, A. K.

10.1101/2021.03.11.434983 — plant biology — Posted on 2021-03-12

2990 Systemic application of the TRPV4 antagonist GSK2193874 induces tail vasodilation in a mouse model of thermoregulation

O'Brien, F.; Staunton, C.; Barrett-Jolley, R.

10.1101/2021.03.12.435126 — physiology — Posted on 2021-03-12

2991 In silico logical modelling to uncover cooperative interactions in cancer

Selvaggio, G.; Chaouiya, C.; Janody, F.

10.1101/2021.03.11.434958 — cancer biology — Posted on 2021-03-12

2992 TP53 loss initiates chromosomal instability in high-grade serous ovarian cancer

Bronder, D.; Wangsa, D.; Zong, D.; Meyer, T. J.; Wardenaar, R.; Minshall, P.; Tighe, A.; Hirsch, D.; Heselmeyer-Haddad, K.; Nelson, L.; Spierings, D.; McGrail, J. C.; Cam, M.; Nussenzweig, A.; Foijer, F.; Ried, T.; Taylor, S. S.

10.1101/2021.03.12.435079 — cancer biology — Posted on 2021-03-12

2993 Markov state models of proton- and gate-dependent activation in a pentameric ligand-gated ion channel

Bergh, C.; Heusser, S. A.; Howard, R. J.; Lindahl, E.

10.1101/2021.03.12.435097 — biophysics — Posted on 2021-03-12

2994 Reconstitution of Kinesin-1 Activation

Chiba, K.; Ori-McKenney, K. M.; Niwa, S.; McKenney, R. J.

10.1101/2021.03.12.434960 — biophysics — Posted on 2021-03-12

2995 Structurally Distributed Surface Sites Tune Allosteric Regulation

McCormick, J. W.; Russo, M. A. X.; Thompson, S.; Blevins, A.; Reynolds, K. A.

10.1101/2021.03.11.435042 — biophysics — Posted on 2021-03-12

2996 A Proposal of New Feature Selection Method Sensitive to Outliers and Correlation

Demirarslan, M.; Suner, A.

10.1101/2021.03.11.434934 — bioinformatics — Posted on 2021-03-12

2997 Pheniqs 2.0: accurate, high performance Bayesian decoding and confidence estimation for combinatorial barcode indexing

Galanti, L.; Shasha, D.; Gunsalus, K.

10.1101/2021.03.11.434956 — bioinformatics — Posted on 2021-03-12

2998 Gene-Gene Interaction Detection with Deep Learning

Cui, T.; El Mekkaoui, K.; Reinvall, J.; Havulinna, A. S.; Marttinen, P.; Kaski, S.

10.1101/2021.03.12.435063 — bioinformatics — Posted on 2021-03-12

2999 Computational Elucidation of Recombinant Fusion Protein Effect on Peptide-Directed Nanoparticles

Polasa, A.; Mosleh, I.; Losey, J.; Abbaspourrad, A.; Beitle, R.; Moradi, M.

10.1101/2021.03.11.432607 — bioengineering — Posted on 2021-03-12

3000 Stereo Slant Discrimination of Planar 3D Surfaces: Standard vs. Planar Cross-Correlation

Oluk, C.; Bonnen, K.; Burge, J.; Cormack, L. K.; Geisler, W. S.

10.1101/2021.03.11.434881 — animal behavior and cognition — Posted on 2021-03-12

3001 Spatial Epigenome Sequencing at Tissue Scale and Cellular Level

Deng, Y.; Zhang, D.; Liu, Y.; Su, G.; Enninful, A.; Bai, Z.; Fan, R.

10.1101/2021.03.11.434985 — genomics — Posted on 2021-03-12

3002 Discovery of Clinically Relevant Fusions in Pediatric Cancer

LaHaye, S.; Fitch, J. R.; Voytovich, K. J.; Herman, A. C.; Kelly, B. J.; Lammi, G. E.; Wijeratne, S.; Franklin, S. J.; Schieffer, K. M.; Bir, N.; McGrath, S. D.; Miller, A. R.; Wetzel, A.; Miller, K. E.; Bedrosian, T. A.; Leraas, K.; Lee, K.; Gupta, A.; Setty, B.; Boue, D. R.; Leonard, J. R.; Finlay, J. L.; Abdelbaki, M. S.; Osorio, D. S.; Koo, S. C.; Koboldt, D. C.; Magrini, V.; Cottrell, C. E.; Mardis, E. R.; Wilson, R. K.; White, P.

10.1101/2021.03.11.435013 — genomics — Posted on 2021-03-12

3003 DNA Preparation In Vitis vinifera L. For Third Generation Sequencing

Bibi, A. C.; Kollias, A.; Astrinaki, M.; Vassou, D.; Kafetzopoulos, D.; Kalantidis, K.; Moschou, P. N.

10.1101/2021.03.11.435003 — genomics — Posted on 2021-03-12

3004 Evolutionary trajectories of three independent neo-sex chromosomes in Drosophila

Nozawa, M.; Minakuchi, Y.; Satomura, K.; Kondo, S.; Toyoda, A.; Tamura, K.

10.1101/2021.03.11.435033 — evolutionary biology — Posted on 2021-03-12

3005 Plant genera Cannabis and Humulus share the same pair of well-differentiated sex chromosomes.

Prentout, D.; Stajner, N.; Cerenak, A.; Tricou, T.; Brochier-Armanet, C.; Jakse, J.; Kafer, J.; Marais, G. A.

10.1101/2021.03.11.434957 — evolutionary biology — Posted on 2021-03-12

3006 Niche shifts and hybridization in two Amazona parrot sister-species introduced to Southern California

Maley, J. M.; Freeland, R. J.; DeRaad, D. A.; Zellmer, A. J.; Schedl, M. E.; Durham, B.; Tsai, W. L. E.; Terrill, R. S.; Sannapareddy, S.; Garrett, K. L.; McCormack, J. E.

10.1101/2021.03.11.435041 — evolutionary biology — Posted on 2021-03-12

3007 Long-term cross-scale comparison of grazing and mowing on plant diversity and community composition in a salt-marsh system

Chen, Q.; Bakker, J. P.; Alberti, J.; Bakker, E. S.; Smit, C.; Olff, H.

10.1101/2021.03.12.435073 — ecology — Posted on 2021-03-12

3008 Temperature and O2, but not CO2, interact to affect aerobic performance of European sea bass (Dicentrarchus labrax)

Montgomery, D. W.; Simpson, S. D.; Davison, W.; Goodrich, H. R.; Engelhard, G. H.; Birchenough, S. N. R.; Wilson, R. W.

10.1101/2021.03.12.435078 — ecology — Posted on 2021-03-12

3009 DNA methylation aging and transcriptomic studies in horses

Horvath, S.; Haghani, A.; Peng, S.; Hales, E. N.; Zoller, J. A.; Raj, K.; Larison, B.; Petersen, J. L.; Bellone, R. R.; Finno, C. J.

10.1101/2021.03.11.435032 — developmental biology — Posted on 2021-03-12

3010 Structure of human Mediator-RNA polymerase II transcription pre-initiation complex

Rengachari, S.; Schilbach, S.; Aibara, S.; Dienemann, C.; Cramer, P.

10.1101/2021.03.11.435010 — molecular biology — Posted on 2021-03-12

3011 The role of copper resistance in Mycobacterium tuberculosis pathogenesis

Ambler, J. M.; Potgieter, M. G.; Klopper, M.; Grobbelaar, M.; De Vos, M.; Sampson, S. L.; Warren, R.; Blackburn, J. M.; Mulder, N.

10.1101/2021.03.11.434961 — microbiology — Posted on 2021-03-12

3012 Measurement of Volatile Compounds for Real-time Analysis of Soil Microbial Metabolic Response to Simulated Snowmelt

Kim, J.; Goldstein, A. H.; Chakraborty, R.; Jardine, K. J.; Weber, R.; Sorensen, P. O.; Wang, S.; Faybishenko, B.; Misztal, P.; Brodie, E. L.

10.1101/2021.03.11.432778 — microbiology — Posted on 2021-03-12

3013 Characterization of the utility of three nebulizers in investigating infectivity of airborne viruses

Niazi, S.; Philp, L. K.; Spann, K.; Johnson, G. R.

10.1101/2021.03.11.435057 — microbiology — Posted on 2021-03-12

3014 NCoR1 and SMRT fine-tune inflammatory versus tolerogenic balance in dendritic cells by differentially regulating STAT3 signaling

Raghav, S. K.; Jha, A.; Ahad, A.; Mishra, G. P.; Sen, K.; Smita, S.; Minz, A. P.; Biswas, V. K.; Tripathy, A.; Senapati, S. B.; Gupta, B.; Orbea, H. A.

10.1101/2021.03.11.434976 — immunology — Posted on 2021-03-12

3015 Ras guanine nucleotide exchange factor RasGRP1 promotes acute inflammatory response and restricts inflammation-contributed cancer cell growth

Wang, C.; Li, X.; Yu, C.; Wang, L.; Deng, R.; Liu, H.; Chen, Z.; Zhang, Y.; Fan, S.; Sun, H.; Zhu, H.; Wang, J.; Tang, S.

10.1101/2021.03.11.434895 — immunology — Posted on 2021-03-12

3016 Reconciliation of theoretical and empirical brain criticality via network heterogeneity

Gu, L.; Ruqian, W.

10.1101/2021.03.11.435016 — neuroscience — Posted on 2021-03-12

3017 Egocentric Asymmetric Coding in Sensory Cortical Border Cells

Long, X.; Deng, B.; Cai, J.; Chen, Z. S.; Zhang, S.-J.

10.1101/2021.03.11.434952 — neuroscience — Posted on 2021-03-12

3018 THINGSvision: a Python toolbox for streamlining the extraction of activations from deep neural networks

Muttenthaler, L.; Hebart, M. N.

10.1101/2021.03.11.434979 — neuroscience — Posted on 2021-03-12

3019 Impairing one sensory modality enhances another by reprogramming peptidergic circuits in Caenorhabditis elegans

Valperga, G.; de Bono, M.

10.1101/2021.03.11.435052 — neuroscience — Posted on 2021-03-12

3020 When shared concept cells support associations: theory of overlapping memory engrams

Gastaldi, C.; Schwalger, T.; De Falco, E.; Quiroga, R. Q.; Gerstner, W.

10.1101/2021.03.12.434964 — neuroscience — Posted on 2021-03-12

3021 Baseline power of theta oscillations predicts mystical-type experiences induced by DMT

Tagliazucchi, E.; Zamberlan, F.; Cavanna, F.; de la Fuente, L. A.; Romero, C.; Sanz Perl, Y.; Pallavicini, C.

10.1101/2021.03.11.434994 — neuroscience — Posted on 2021-03-12

3022 Nicotinamide riboside alleviates Parkinson's disease symptoms but downregulates dopamine metabolism upon lactacystin-induced proteostasis failure

Turconi, G.; Alam, F.; SenGupta, T.; Pirnes-Karhu, S.; Olfat, S.; Schmidt, M. S.; Mätlik, K.; Montano-Rodriguez, A.; Heiskanen, V.; Piepponen, P. T.; Brenner, C.; Holmberg, C. I.; Nilsen, H.; Andressoo, J.-O.; Pirinen, E.

10.1101/2021.03.12.435062 — neuroscience — Posted on 2021-03-12

3023 Central tendency biases must be accounted for to consistently capture Bayesian cue combination in continuous response data

Aston, S.; Negen, J.; Nardini, M.; Beierholm, U.

10.1101/2021.03.12.434970 — neuroscience — Posted on 2021-03-12

3024 A cell-ECM mechanism for connecting the ipsilateral eye to the brain

Su, J.; Liang, Y.; Sabbagh, U.; Olejnikova, L.; Russell, A. L.; Chen, J.; Pan, Y. A.; Triplett, J. W.; Fox, M. A.

10.1101/2021.03.11.434782 — neuroscience — Posted on 2021-03-12

3025 PBN-PVT projection modulates negative emotions in mice

Zhu, Y.-B.; Zhang, R.; Wang, Y.; Liu, P.-F.; Li, J.-B.; Mu, D.

10.1101/2021.03.11.434900 — neuroscience — Posted on 2021-03-12

3026 Examination of the contribution of Nav1.7 to axonal propagation in nociceptors

Goodwin, G.; McMurray, S.; Stephens, E. B.; Denk, F. L.; McMahon, S. B.

10.1101/2021.03.12.435114 — neuroscience — Posted on 2021-03-12

3027 Effects of long-term high-temperature stress on reproductive growth and seed development in development in Brassica napus

Macova, K.; Prabhullachandran, U.; Spyroglou, I.; Stefkova, M.; Pencik, A.; Endlova, L.; Novak, O.; Robert, H. S.

10.1101/2021.03.11.434971 — plant biology — Posted on 2021-03-12

3028 Embryo development in Carica papaya Linn

Benavides-Acevedo, M.; Bolanos-Villegas, P.

10.1101/2021.03.11.434975 — plant biology — Posted on 2021-03-12

3029 Adipocyte Tribbles1 Regulates Plasma Adiponectin and Plasma Lipids in Mice

Ha, E. E.; Quartuccia, G. I.; Ling, R.; Xue, C.; Hernandez-Ono, A.; Imam, R.; Cui, J.; Soni, R. K.; Bauer, R. C.

10.1101/2021.03.11.434882 — physiology — Posted on 2021-03-12

3030 Whole-organism 3D Quantitative Characterization of Zebrafish Melanin by Silver Deposition Micro-CT

Katz, S. R.; Yakovlev, M. A.; Vanselow, D. J.; Ding, Y.; Lin, A. Y.; Parkinson, D. Y.; Wang, Y.; Canfield, V. A.; Ang, K. C.; Cheng, K. C.

10.1101/2021.03.11.434673 — pathology — Posted on 2021-03-12

3031 Relevance of Circulating Hybrid Cells as a Non-Invasive Biomarker for Myriad Solid Tumors

Dietz, M. S.; Sutton, T. L.; Walker, B. S.; Gast, C. E.; Zarour, L.; Sengupta, S. K.; Swain, J. R.; Eng, J.; Parappilly, M.; Limbach, K.; Sattler, A.; Burlingame, E.; Chin, Y.; Gower, A.; Montoya Mira, J. L.; Sapre, A.; Chiu, Y.-J.; Clayburgh, D. R.; Pommier, S. J.; Cetnar, J. P.; Fischer, J. M.; Jaboin, J. J.; Pommier, R. F.; Sheppard, B. C.; Tsikitis, V. L.; Skalet, A. H.; Mayo, S. C.; Lopez, C. D.; Gray, J. W.; Mills, G. B.; Mitri, Z.; Chang, Y. H.; Chin, K.; Wong, M. H.

10.1101/2021.03.11.434896 — cancer biology — Posted on 2021-03-12

3032 Refget: standardised access to reference sequences

Yates, A. D.; Adams, J.; Chaturvedi, S.; Davies, R. M.; Laird, M.; Leinonen, R.; Nag, R.; Sheffield, N. C.; Hofmann, O.; Keane, T.

10.1101/2021.03.11.434800 — bioinformatics — Posted on 2021-03-12

3033 Guidance for RNA-seq co-expression estimates: the importance of data normalization, batch effects, and correlation measures

Vandenbon, A.

10.1101/2021.03.11.435043 — bioinformatics — Posted on 2021-03-12

3034 Deep learning from phylogenies to uncover the transmission dynamics of epidemics

Voznica, J.; Zhukova, A.; Boskova, V.; Saulnier, E.; Lemoine, F.; Moslonka-Lefebvre, M.; Gascuel, O.

10.1101/2021.03.11.435006 — bioinformatics — Posted on 2021-03-12

3035 Characterization of a haplotype-reference panel for genotyping by low-pass sequencing in Swiss Large White pigs

Noskova, A.; Bhati, M.; Kadri, N. K.; Crysnanto, D.; Neuenschwander, S.; Hofer, A.; Pausch, H.

10.1101/2021.03.11.434987 — genomics — Posted on 2021-03-12

3036 Two distinct mechanisms underlie dosage sensitivity in Pumilio1-associated diseases

Botta, S.; de Prisco, N.; Chemiakine, A.; Cabaj, M.; Brandt, V. L.; Patel, P.; Soni, R. K.; Gennarino, V. A.

10.1101/2021.03.11.435015 — genetics — Posted on 2021-03-12

3037 Reevaluating claims of ecological speciation in Halichoeres bivittatus

Warren, D. L.; Eytan, R. I.; Dornburg, A.; Iglesias, T. L.; Brandley, M. C.; Wainwright, P. C.

10.1101/2021.03.11.435027 — evolutionary biology — Posted on 2021-03-12

3038 Understanding the Evolution of Nutritive Taste in Animals: Insights from Biological Stoichiometry and Nutritional Geometry

Demi, L. M.; Taylor, B. W.; Reading, B. J.; Tordoff, M. G.; Dunn, R. R.

10.1101/2021.03.11.434999 — evolutionary biology — Posted on 2021-03-12

3039 Optimal immune specificity at the intersection of host life history and parasite epidemiology

Downie, A. E.; Mayer, A.; Metcalf, C. J. E.; Graham, A. L.

10.1101/2021.03.11.434955 — ecology — Posted on 2021-03-12

3040 Intergenerational Effects of Early Life Starvation on Life-History, Consumption, and Transcriptomes of a Holometabolous Insect

Paul, S. C.; Singh, P.; Dennis, A.; Mueller, C.

10.1101/2021.03.11.434967 — ecology — Posted on 2021-03-12

3041 Nonlinear averaging in 2D: intraspecific variation in two interacting species and consequences for population dynamics

van Benthem, K. J.; Bagawade, R.; Blüml, C.; Nabutanyi, P.; Thon, F. M.; Wittmann, M. J.

10.1101/2021.03.11.435001 — ecology — Posted on 2021-03-12

3042 TNF Blockade Reduces Prostatic Hyperplasia and Inflammation while Limiting BPH Diagnosis in Patients with Autoimmune Disease

Vickman, R. E.; Aaron-Brooks, L.; Zhang, R.; Lanman, N. A.; Lapin, B.; Gil, V.; Greenberg, M.; Sasaki, T.; Cresswell, G. M.; Broman, M. M.; Petkewicz, J.; Talaty, P.; Helfand, B. T.; Glaser, A. P.; Wang, C.-H.; Franco, O. E.; Ratliff, T. L.; Nastiuk, K. L.; Crawford, S. E.; Hayward, S. W.

10.1101/2021.03.11.434972 — cell biology — Posted on 2021-03-12

3043 Surf4 Promotes Endoplasmic Reticulum Exit of the Lysosomal Prosaposin-Progranulin Complex

Devireddy, S.; Ferguson, S.

10.1101/2021.03.11.435014 — cell biology — Posted on 2021-03-12

3044 Effect of natural mutations of SARS-CoV-2 on spike structure, conformation and antigenicity

Gobeil, S.; Janowska, K.; McDowell, S.; Mansouri, K.; Parks, R.; Stalls, V.; Kopp, M. F.; Manne, K.; Saunders, K. O.; Edwards, R. J.; Haynes, B. F.; Henderson, R.; Acharya, P.

10.1101/2021.03.11.435037 — microbiology — Posted on 2021-03-12

3045 Inhibitors of the Small Membrane (M) Protein Viroporin Prevent Zika Virus Infection

Brown, E.; Lefteri, D.; Singh, R.; Thompson, R.; Maskell, D.; Beaumont, H.; Bentham, M. J.; Swinscoe, G.; Merits, A.; Donald, C.; Kohl, A.; Macdonald, A.; Ranson, N.; Foster, R.; McKimmie, C. S.; Kalli, A. C.; Griffin, S. C.

10.1101/2021.03.11.435022 — microbiology — Posted on 2021-03-12

3046 Combination adjuvants enhance recombinant protein vaccine protection against fungal infection

Wuethrich, M.; Dobson, H. E.; Ledesma Taira, C.; Okaa, U. J.; Petrovsky, N.; Klein, B. S.

10.1101/2021.03.11.434977 — immunology — Posted on 2021-03-12

3047 Neural Correlates of Reactivation and Vividness Reveal Separable Contributions to Objective and Subjective Measures of Episodic Memory

Barker, R. M.; St-Laurent, M.; Buchsbaum, B. R.

10.1101/2021.03.11.434635 — neuroscience — Posted on 2021-03-12

3048 Protocol-Dependence of Middle Cerebral Artery Dilation to Modest Hypercapnia

Al-Khazraji, B. K.; Buch, S.; Kadem, M.; Matushewski, B. J.; Norozi, K.; Menon, R. S.; Shoemaker, J. K.

10.1101/2021.03.11.434655 — physiology — Posted on 2021-03-12

3049 Cargo crowding, stationary clusters and dynamical reservoirs in axonal transport

Kumar, V.; Vasudevan, A.; Venkatesh, K.; Maiya, R.; Sood, P.; Murthy, K.; Koushika, S. P.; Menon, G. I.

10.1101/2021.03.12.434740 — biophysics — Posted on 2021-03-12

3050 Hematopoietic progenitors passing through early embryonic CD4-positive stage are long-lived and give rise to myeloid and lymphoid progeny

Apostolov, A. K.; Marie, J. C.

10.1101/2021.03.02.433212 — developmental biology — Posted on 2021-03-12

3051 YAP1 Regulates the Self-organized Fate Patterning of hESCs-Derived Gastruloids

Giraldez, S.; Stronati, E.; Huang, L.; Hsu, H.-T.; Abraham, E.; Jones, K. A.; Estaras, C.

10.1101/2021.03.12.434631 — developmental biology — Posted on 2021-03-12

3052 BioISO: an objective-oriented application for assisting the curation of genome-scale metabolic models

Cruz, F.; Capela, J.; Ferreira, E. C.; Rocha, M.; Dias, O.

10.1101/2021.03.07.434259 — systems biology — Posted on 2021-03-12

3053 Extracellular matrix gene expression signatures as cell type and cell state identifiers

Sacher, F.; Feregrino, C.; Tschopp, P.; Ewald, C. Y.

10.1101/2021.03.11.434939 — systems biology — Posted on 2021-03-12

3054 Transmembrane Kinases are essential for plant development

Li, Q.; Yang, J.; Zhang, Y.; Wang, F.; Chang, M.; Xu, T.; Wang, S.; He, J.

10.1101/2021.03.11.434919 — plant biology — Posted on 2021-03-12

3055 Chronic exercise protects against the progression of renal cyst growth and dysfunction in rats with polycystic kidney disease

Qiu, J.; Sato, Y.; Xu, L.; Miura, T.; Kohzuki, M.; Ito, O.

10.1101/2021.03.11.434857 — physiology — Posted on 2021-03-12

3056 The pangenome of the fungal pathogen Neonectria neomacrospora

Nielsen, K. N.; Siren, K.; Petersen, B.; Sicheritz-Ponten, T.; Gilbert, M. T. P.; Korneliussen, T. S.; Hansen, O. K.

10.1101/2021.03.11.434922 — genomics — Posted on 2021-03-12

3057 Epigenetic switching outcompetes genetic mutations during adaptation to fluctuating environments

Stajic, D.; Bank, C.; Gordo, I.

10.1101/2021.03.11.434930 — evolutionary biology — Posted on 2021-03-12

3058 kinesin recruitment by adapter SKIP on melanosomes is dynamically controlled by LC3B phosphorylation

Subramaniam, Y. J.; Murthy, D.; Raja, A. D.; Ramkumar, A.; Sivasubbu, S.; McEwan, D. G.; Gokhale, R. S.; Natarajan, V.

10.1101/2021.03.11.434917 — cell biology — Posted on 2021-03-12

3059 TRIPLE-NEGATIVE BREAST CANCER CELLS RECRUIT NEUTROPHILS BY SECRETING TGF-β AND CXCR2 LIGANDS

SENGUPTA, S.; Hein, L. E.; Xu, Y.; Zhang, J.; Konwerski, J.; Li, Y.; Johnson, C.; Cai, D.; Smith, J.; Parent, C. A.

10.1101/2021.01.28.428630 — immunology — Posted on 2021-03-12

3060 Seronegative MSM at high-risk of HIV-1 acquisition show Immune quiescent profile with normal immune response against common antigens

Ossa-Giraldo, A.; Blanquiceth, Y.; Florez-Alvarez, L.; Contreras-Ramirez, K.; Rojas, M.; Hernandez, J. C.; Zapata-Builes, W.

10.1101/2021.03.11.434877 — immunology — Posted on 2021-03-12

3061 Profiling of cytokines, chemokines and growth factors in saliva and gingival crevicular fluid

Liu, Y.; Zhao, R.; Reda, B.; Reda, B.; Yang, W.; Qu, B.

10.1101/2021.03.11.434959 — immunology — Posted on 2021-03-12

3062 Direct Extraction of Signal and Noise Correlations from Two-Photon Calcium Imaging of Ensemble Neuronal Activity

Rupasinghe, A.; Francis, N.; Liu, J.; Bowen, Z.; O. Kanold, P.; Babadi, B.

10.1101/2021.03.11.434932 — neuroscience — Posted on 2021-03-12

3063 From synaptic activity to human in vivo quantification of neurotransmitter dynamics: a neural modelling approach

Lea-Carnall, C. A.; El-Deredy, W.; Williams, S. R.; Stagg, C. J.; Trujillo-Barreto, N. J.

10.1101/2021.03.11.434540 — neuroscience — Posted on 2021-03-12

3064 A survey of the mouse hindbrain in the fed and fasted state using single-nucleus RNA sequencing

Dowsett, G. K. C.; Lam, B. Y. H.; Tadross, J. A.; Cimino, I.; Rimmington, D.; Coll, A.; Polex-Wolf, J.; Knudsen, L. B.; Pyke, C.; Yeo, G. S. H.

10.1101/2021.03.11.434948 — neuroscience — Posted on 2021-03-12

3065 Value signals in orbitofrontal cortex predict economic decisions on a trial-to-trial basis

McGinty, V. B.; Lupkin, S. M.

10.1101/2021.03.11.434452 — neuroscience — Posted on 2021-03-12

3066 The Interaction of Angiotensin II and Milk Fat Globule Epidermal Growth Factor VIII in Proinflammatory Arterial Remodeling

Ni, L.; Liu, L.; Zhu, W.; Telljohann, R.; Zhang, J.; Monticone, R. E.; McCraw, K. R.; Liu, C.; Morrell, C. H.; Lakatta, E. G.; Wang, m.

10.1101/2021.03.11.434767 — pathology — Posted on 2021-03-12

3067 Propranolol reduces sarcoma growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment

Fjaestad, K. Y.; Askehoj Romer, A. M.; Goitea, V.; Zedlitz Johansen, A.; Thorseth, M.-L.; Carretta, M.; Henning Engelholm, L.; Grontved, L.; Junker, N.; Hargbol Madsen, D.

10.1101/2021.03.11.434711 — cancer biology — Posted on 2021-03-12

3068 A hydro-osmotic coarsening theory of biological cavity formation

Le Verge--Serandour, M.; Turlier, H.

10.1101/2020.12.01.406991 — biophysics — Posted on 2021-03-12

3069 Virtue as the mean: Pan-human consensus genome significantly improves the accuracy of RNA-seq analyses

Kaminow, B.; Ballouz, S.; Gillis, J.; Dobin, A.

10.1101/2020.12.22.423111 — bioinformatics — Posted on 2021-03-12

3070 A randomization-based causal inference framework for uncovering environmental exposure effects on human gut microbiota

Sommer, A. J.; Peters, A.; Rommel, M.; Cyrys, J.; Grallert, H.; Haller, D.; Müller, C. L.; Bind, M.-A. C.

10.1101/2021.02.24.432662 — bioinformatics — Posted on 2021-03-12

3071 Exponentiating pixel values for data augmentation to improve deep learning image classification in chest X-rays

Usuzaki, T.; Takahashi, K.; Shimokawa, D.; Shibuya, K.

10.1101/2021.03.11.434925 — bioinformatics — Posted on 2021-03-12

3072 Deeplasmid: Deep learning accurately separates plasmids from bacterial chromosomes

Andreopoulos, W. B.; Geller, A. M.; Lucke, M.; Balewski, J.; Clum, A.; Ivanova, N.; Levy, A.

10.1101/2021.03.11.434936 — bioinformatics — Posted on 2021-03-12

3073 The mutational signatures of formalin fixation on the human genome

Guo, Q.; Lakatos, E.; Al Bakir, I.; Curtius, K.; Graham, T. A.; Mustonen, V.

10.1101/2021.03.11.434918 — bioinformatics — Posted on 2021-03-12

3074 Multichromatic Near-Infrared Imaging to Assess Interstitial Lymphatic and Venous Uptake In Vivo

Bernard, F. C.; Kaiser, J.; Raval, S. K.; Nepiyushchikh, Z. V.; Doan, T. N.; Willett, N. J.; Dixon, J. B.

10.1101/2021.03.07.434298 — bioengineering — Posted on 2021-03-12

3075 3D soft hydrogels induce human mesenchymal stem cells "deep" quiescence

Boaventura Gomes, D.; Henriques Lourenco, A. F.; Tomasina, C.; Chompff, B.; Liu, H.; Bouvy, N.; Camarero-Espinosa, S.; Moroni, L.

10.1101/2021.03.11.434638 — bioengineering — Posted on 2021-03-12

3076 Single molecule imaging reveals the collective and independent search mechanisms of cFos and cJun on DNA

Leech, J. T.; Brennan, A.; Don, N. A.; Mason, J. M.; Kad, N. M.

10.1101/2020.01.24.918300 — biochemistry — Posted on 2021-03-12

3077 Single Cell Transcriptomic Landscape of Diabetic Foot Ulcers

Theocharidis, G.; Thomas, B. E.; Sarkar, D.; Pilcher, W. J.; Dwivedi, B.; Sandoval-Schaefer, T.; Sirbulescu, R. F.; Kafanas, A.; Mezghani, I.; Wang, P.; Lobao, A.; Vlachos, I.; Dash, B.; Hsia, H. C.; Horsley, V.; Bhasin, S. S.; Veves, A.; Bhasin, M.

10.1101/2021.03.11.434413 — genomics — Posted on 2021-03-12

3078 mTOR-activating mutations in RRAGD cause kidney tubulopathy and cardiomyopathy (KICA) syndrome

Schlingmann, K. P.; Jouret, F.; Shen, K.; Nigam, A.; Arjona, F. J.; Dafinger, C.; Houillier, P.; Jones, D. P.; Kleinerueschkamp, F.; Oh, J.; Godefroid, N.; Eltan, M.; Guran, T.; Burtey, S.; Parotte, M.-C.; Koenig, J.; Braun, A.; Bos, C.; Ibars Serra, M.; Rehmann, H.; Zwartkruis, F. J. T.; Renkema, K. Y.; Klingel, K.; Schulze-Bahr, E.; Schermer, B.; Bergmann, C.; Altmueller, J.; Thiele, H.; Beck, B. B.; Dahan, K.; Sabatini, D.; Liebau, M. C.; Vargas-Poussou, R.; Knoers, N. V. A. M.; Konrad, M.; de Baaij, J. H. F.

10.1101/2021.03.11.434334 — genetics — Posted on 2021-03-12

3079 Mapping the genetic and environmental aetiology of autistic traits in Sweden and the UK

Reed, Z. E.; Larsson, H.; Haworth, C. M. A.; Rai, D.; Lundstrom, S.; Ronald, A.; Reichenberg, A.; Lichtenstein, P.; Davis, O. S. P.

10.1101/2020.04.14.031518 — genetics — Posted on 2021-03-12

3080 MR-APSS: a unified approach to Mendelian Randomization accounting for pleiotropy and sample structure using genome-wide summary statistics

Hu, X.; Zhao, J.; Lin, Z.; Wang, Y.; Peng, H.; Zhao, H.; Wan, X.; Yang, C.

10.1101/2021.03.11.434915 — genetics — Posted on 2021-03-12

3081 In the absence of reproductive isolation - Extensive gene flow after speciation

Wang, X.; Guo, Z.; He, Z.; Xu, S.; Shao, S.; Li, S.; Yang, M.; Chen, Q.; Wu, Z.; Zhong, C.; Duke, N. C.; Shi, S.

10.1101/622019 — evolutionary biology — Posted on 2021-03-12

3082 The genetic variation landscape of African swine fever virus reveals frequent positive selection and adaptive flexibility

Bao, Y.-J.; Qiu, J.; Luo, Y.; Rodriguez, F.; Qiu, H.-J.

10.1101/2020.08.12.249045 — evolutionary biology — Posted on 2021-03-12

3083 Effects of fine-scale population structure on inbreeding in a long-term study of snapdragons (Antirrhinum majus)

Arathoon, L.; Surendranadh, P.; Barton, N.; Field, D. L.; Pickup, M.; Baskett, C. A.

10.1101/2020.08.20.259036 — evolutionary biology — Posted on 2021-03-12

3084 Can citizen science analysis of camera trap data be used to study reproduction? Lessons from Snapshot Serengeti program

Thel, L.; Chamaille-Jammes, S.; Keurinck, L.; Catala, M.; Packer, C.; Huebner, S.; Bonenfant, C.

10.1101/2020.11.30.400804 — ecology — Posted on 2021-03-12

3085 A cross-nearest neighbor/Monte Carlo algorithm for single molecule localization microscopy defines interactions between p53, Mdm2, and MEG3

Bauer, N. C.; Yang, A.; Wang, X.; Zhou, Y.; Klibanski, A.; Soberman, R. J.

10.1101/857912 — cell biology — Posted on 2021-03-12

3086 Chromatin reader Dido3 regulates the genetic network of B cell differentiation

Gutierrez del Burgo, F.; Pons, T.; Vazquez de Luis, E.; Martinez-A, C.; Villares, R.

10.1101/2021.02.23.432411 — molecular biology — Posted on 2021-03-12

3087 A novel combination of Class-I fumarases and metabolites (α-ketoglutarate and fumarate) signal the DNA damage response in E. coli.

Silas, Y.; Singer, E.; Lehming, N.; Pines, O.

10.1101/2020.08.04.232652 — microbiology — Posted on 2021-03-12

3088 Taxonomy of neural oscillation events in primate auditory cortex

Neymotin, S. A.; Tal, I.; Barczak, A.; O'Connell, M. N.; McGinnis, T.; Markowitz, N.; Espinal, E.; Griffith, E.; Anwar, H.; Dura-Bernal, S.; Schroeder, C. E.; Lytton, W. W.; Jones, S. R.; Bickel, S.; Lakatos, P.

10.1101/2020.04.16.045021 — neuroscience — Posted on 2021-03-12

3089 Embedding optimization reveals long-lasting history dependence in neural spiking activity

Rudelt, L.; Gonzales Marx, D.; Wibral, M.; Priesemann, V.

10.1101/2020.11.05.369306 — neuroscience — Posted on 2021-03-12

3090 Developmental depression-facilitation shift controls excitation-inhibition balance

Jia, D. W.; Costa, R. P.; Vogels, T. P.

10.1101/2021.02.23.431593 — neuroscience — Posted on 2021-03-12

3091 A network linking scene perception and spatial memory systems in posterior cerebral cortex

Steel, A.; Billings, M. M.; Silson, E. H.; Robertson, C. E.

10.1101/2020.05.25.115147 — neuroscience — Posted on 2021-03-12

3092 Disrupted PDZ-domain binding motif of the dopamine transporter uniquely alters nanoscale distribution, dopamine homeostasis and reward motivation

Sorensen, G.; Rickhag, M.; Leo, D.; Lycas, M. D.; Ridderstrom, P. H.; Weikop, P.; Herborg, F. H.; Woldbye, D. P.; Wortwein, G.; Gainetdinov, R. R.; Fink-Jensen, A.; Gether, U.

10.1101/2021.01.06.425643 — neuroscience — Posted on 2021-03-12

3093 Integrated multi-omics analysis reveals common and distinct dysregulated pathways for genetic subtypes of Frontotemporal Dementia

Menden, K.; Francescatto, M.; Niyma, T.; Blauwendraat, C.; Dhingra, A.; Castillo Lizardo, M.; Fernandes, N.; Kaurani, L.; Kronenberg-Versteeg, D.; Atarsu, B.; Sadikoglou, E.; Borroni, B.; Rodriguez Nieto, S.; Simon Sanchez, J.; Fischer, A.; Craig, D. W.; Neumann, M.; Bonn, S.; Rizzu, P.; Heutink, P.

10.1101/2020.12.01.405894 — neuroscience — Posted on 2021-03-12

3094 A single synonymous nucleotide change impacts the male-killing phenotype of prophage WO gene wmk

Perlmutter, J.; Bordenstein, S. R.; Meyers, J. E.

10.1101/2021.03.11.434916 — genomics — Posted on 2021-03-12

3095 REPRODUCTIVE SENESCENCE IMPAIRS THE ENERGY METABOLISM OF HUMAN GRANULOSA CELLS

Cecchino, G. N.; Garcia-Velasco, J. A.; Rial, E.

10.1101/2021.03.11.434795 — cell biology — Posted on 2021-03-12

3096 Transient Kinetic Proofreading

Iyengar, G.; Perry, M.

10.1101/2021.03.10.434642 — immunology — Posted on 2021-03-12

3097 Paradoxical relationship between speed and accuracy in olfactory figure-background segregation

Lebovich, L.; Yunerman, M.; Scaiewicz, V.; Loewenstein, Y.; Rokni, D.

10.1101/2021.03.10.434790 — neuroscience — Posted on 2021-03-12

3098 Human primary visual cortex shows larger population receptive fields for binocular disparity-defined stimuli

Alvarez, I.; Hurley, S. A.; Parker, A. J.; Bridge, H.

10.1101/2021.03.10.434843 — neuroscience — Posted on 2021-03-12

3099 A rapid and efficient learning rule for biological neural circuits

Sezener, E.; Grabska-Barwinska, A.; Kostadinov, D.; Beau, M.; Krishnagopal, S.; Budden, D.; Hutter, M.; Veness, J.; Botvinick, M.; Clopath, C.; Hausser, M.; Latham, P.

10.1101/2021.03.10.434756 — neuroscience — Posted on 2021-03-12

3100 The dynamics of decision making and action during active sampling

Ozbagci, D.; Moreno-Bote, R.; Soto-Faraco, S.

10.1101/2021.03.10.434801 — neuroscience — Posted on 2021-03-12

3101 Forced swim stress dynamically alters neural activity and bi-directionally modulates NMDA receptors in the prefrontal cortex

Parent, M.-A. L. T.; Lockridge, A.; Yuan, L.-L.

10.1101/2021.03.10.434848 — neuroscience — Posted on 2021-03-12

3102 Bayesian Multivariate Growth Mixture Modeling of Longitudinal Data: An Application to Alzheimer's Disease Study

Lin, W.; Donohue, M. C.; Insel, P.; Schwartzman, A.; Thompson, W. K.

10.1101/2021.03.10.434854 — neuroscience — Posted on 2021-03-12

3103 Single-trial-based Temporal Principal Component Analysis on Extracting Event-related Potentials of Interest for an Individual Subject

zhang, g.; Li, X.; Lu, Y.; Tiihonen, T.; Chang, Z.; Cong, F.

10.1101/2021.03.10.434892 — neuroscience — Posted on 2021-03-12

3104 Bidirectional modulation of pain-related behaviors in the zona incerta

Singh, S.; Valdivia, S.; Soler-Cedeno, O.; Adke, A. P.; Benowitz, B.; Velasquez, D.; Wilson, T. D.; Carrasquillo, Y.

10.1101/2021.03.10.434888 — neuroscience — Posted on 2021-03-12

3105 Systems-level network modeling deciphers the master regulators of phenotypic plasticity and heterogeneity in melanoma

Pillai, M.; Jolly, M. K.

10.1101/2021.03.11.434533 — systems biology — Posted on 2021-03-12

3106 Osteoarthritis Early-, Mid- and Late-Stage Progression in the Rat Medial Meniscus Transection Model

Doan, T. N.; McKinney, J.; Pucha, K.; Bernard, F.; Willett, N.

10.1101/2021.03.11.434909 — pathology — Posted on 2021-03-12

3107 On the generality and cognitive basis of base-rate neglect

Stengard, E.; Juslin, P.; Hahn, U.; van den Berg, R.

10.1101/2021.03.11.434913 — animal behavior and cognition — Posted on 2021-03-12

3108 Sequence features around cleavage sites are highly conserved among different species and a critical determinant for RNA cleavage position across eukaryotes

Ueno, D.; Yamasaki, S.; Sadakiyo, Y.; Teruyama, T.; Demura, T.; Kato, K.

10.1101/2021.03.10.434873 — bioinformatics — Posted on 2021-03-12

3109 Interaction of micropatterned topographical and biochemical cues to direct neurite growth from spiral ganglion neurons

Truong, K.; Leigh, B.; Vecchi, J. T.; Bartholomew, R.; Xu, L.; Guymon, C. A.; Hansen, M. R.

10.1101/2021.03.10.434606 — bioengineering — Posted on 2021-03-12

3110 Genomic Prediction in Family Bulks Using Different Traits and Cross-Validations in Pine

Rios, E.; Murad Leite Andrade, M. H.; de Resende Junior, M. F. R.; Kirst, M.; de Resende, M. D. V.; de Almeida Filho, J. E.; Gezan, S. A.; Munoz, P.

10.1101/2021.03.10.434809 — genomics — Posted on 2021-03-12

3111 Pathogenic MAST3 variants in the STK domain are associated with epilepsy

Spinelli, E.; Christensen, K.; Bryant, E.; Schneider, A.; Rakotomamonjy, J.; Muir, A.; Giannelli, J.; Littlejohn, R.; Roeder, E.; Schmidt, B.; Wilson, W.; Marco, E.; Iwama, K.; Kumada, S.; Pisano, T.; Barba, C.; Brilstra, E.; van Jaarsveld, R.; Matusmoto, N.; Rodan, L.; McWalter, K.; Guerrini, R.; Scheffer, I.; Mefford, H.; Mandelstam, S.; Laux, L.; Millichap, J.; Guemez-Gamboa, A.; Nairn, A.; Carvill, G.

10.1101/2021.03.09.434675 — genetics — Posted on 2021-03-12

3112 Alpha satellite insertions and the evolutionary landscape of centromeres

Giannuzzi, G.; Logsdon, G. A.; CHATRON, N.; Miller, D. E.; Reversat, J.; Munson, K. M.; Hoekzema, K.; Bonnet-Dupeyron, M.-N.; Rollat-Farnier, P.-A.; Baker, C. A.; Sanlaville, D.; Eichler, E. E.; Schluth-Bolard, C.; Reymond, A.

10.1101/2021.03.10.434819 — genetics — Posted on 2021-03-12

3113 Contribution of SARS-CoV-2 accessory proteins to viral pathogenicity in K18 hACE2 transgenic mice

Silvas, J.; Morales Vasquez, D.; Park, J.-G.; Chiem, K.; Torrelles, J.; Platt, R. N.; Anderson, T.; Ye, C.; Martinez-Sobrido, L.

10.1101/2021.03.09.434696 — microbiology — Posted on 2021-03-12

3114 Interferons Reshape the 3D Conformation and Accessibility of Macrophage Chromatin

Platanitis, E.; Güner, S.; Geetha, A. R. S. J.; Boccuni, L.; Vogt, A.; Novatchkova, M.; Sommer, A.; Müller, M.; Decker, T.

10.1101/2021.03.09.434568 — immunology — Posted on 2021-03-12

3115 Probable omnigenic effect and evolutionary insights of aerobic adaptation allele OsNCED2T on qDTY12.1 effecting grain yield under reproductive stage drought stress in rice

Chidambaranathan, P.; Balasubramaniasai, C.; Samantaray, S.; Annamalai, A.; Katara, J. L.; BN, D.; Kumar, A.; Jeughale, K.; Sahoo, B.; Behura, N.; Behera, B.

10.1101/2021.03.10.434074 — plant biology — Posted on 2021-03-12

3116 mTOR-activating mutations in RRAGD cause kidney tubulopathy and cardiomyopathy (KICA) syndrome

Schlingmann, K. P.; Jouret, F.; Shen, K.; Nigam, A.; Arjona, F. J.; Dafinger, C.; Houillier, P.; Jones, D. P.; Kleinerueschkamp, F.; Oh, J.; Godefroid, N.; Eltan, M.; Guran, T.; Burtey, S.; Parotte, M.-C.; Koenig, J.; Braun, A.; Bos, C.; Ibars Serra, M.; Rehmann, H.; Zwartkruis, F. J. T.; Renkema, K. Y.; Klingel, K.; Schulze-Bahr, E.; Schermer, B.; Bergmann, C.; Altmueller, J.; Thiele, H.; Beck, B. B.; Dahan, K.; Sabatini, D.; Libau, M. C.; Vargas-Poussou, R.; Knoers, N. V. A. M.; Konrad, M.; de Baaij, J. H. F.

10.1101/2021.03.11.434334 — genetics — Posted on 2021-03-12

3117 Early mechanisms of whisker development: Prdm1 and its regulation in whisker development and evolutionary loss

Manti, P. G.; Darbellay, F.; Leleu, M.; Moret, B.; Cuennet, J.; Droux, F.; Stoudmann, M.; Mancini, G.; Hautier, A.; Barrandon, Y.

10.1101/2021.03.11.433122 — developmental biology — Posted on 2021-03-12

3118 Notch signaling via Hey1 and Id2b regulates Müller glia's regenerative response to retinal injury

Goldman, D.; Sahu, A.; Devi, S.; Jui, J.

10.1101/2021.03.11.435053 — developmental biology — Posted on 2021-03-12

3119 Inactivation of Aβ42 Protomer-dimer Dissociation Reaction via Increasing Protomer Size

Kurisaki, I.; Tanaka, S.

10.1101/2021.02.12.431048 — biophysics — Posted on 2021-03-12

3120 Recovery of high-quality assembled genomes via metagenome binning guided with single-cell amplified genomes

Arikawa, K.; Ide, K.; Kogawa, M.; Saeki, T.; Yoda, T.; Endoh, T.; Matsuhashi, A.; Takeyama, H.; Hosokawa, M.

10.1101/2021.01.11.425816 — microbiology — Posted on 2021-03-12

3121 SpecHap: a diploid phasing algorithm based on spectral graph theory

Yu, Y.; Chen, L.; Miao, X.; Li, S.

10.1101/870972 — bioinformatics — Posted on 2021-03-12

3122 Elucidating the Molecular Basis of pH Activation of an Engineered Mechanosensitive Channel

Immadisetty, K.; Polasa, A.; Shelton, R.; Moradi, M.

10.1101/707794 — biophysics — Posted on 2021-03-11

3123 Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness

Kowalczyk, A.; Chikina, M.; Clark, N.

10.1101/2021.03.11.434984 — evolutionary biology — Posted on 2021-03-11

3124 A genome-annotated bacterial collection of the barley rhizosphere microbiota

Robertson-Albertyn, S.; Concas, F.; Brown, L. H.; Orr, J. N.; Abbott, J. C.; George, T. S.; Bulgarelli, D.

10.1101/2021.03.10.434690 — microbiology — Posted on 2021-03-11

3125 Identifying regions in prefrontal cortex related to working memory improvement: a novel meta-analytic method using electric field modeling

Wischnewski, M.; Mantell, K. E.; Opitz, A.

10.1101/2021.03.11.435002 — neuroscience — Posted on 2021-03-11

3126 Information flows from hippocampus to cortex during replay of verbal working memory items.

Dimakopoulos, V. S.; Stieglitz, L.; Megevand, P.; Sarnthein, J.

10.1101/2021.03.11.434989 — neuroscience — Posted on 2021-03-11

3127 A meta-analysis of effects of feeding seaweed on beef and dairy cattle performance and methane yield

Golder, H. M.; Lean, I. J.; Grant, T. M. D.; Moate, P. J.

10.1101/2021.03.11.434923 — scientific communication and education — Posted on 2021-03-11

3128 Two Genomic Loci Control Three Eye Colors in the Domestic Pigeon (Columba livia)

Maclary, E. T.; Phillips, B.; Wauer, R.; Boer, E. F.; Bruders, R.; Gilvarry, T.; Holt, C.; Yandell, M.; Shapiro, M. D.

10.1101/2021.03.11.434326 — genetics — Posted on 2021-03-11

3129 Rapid tissue-specific screening of Wolbachia, Cardinium and Rickettsia in Flies (Diptera: Sepsidae; Drosophilidae)

Wei Yuan, C.; Huicong, D.; Puniamoorthy, N.

10.1101/2021.03.11.434924 — evolutionary biology — Posted on 2021-03-11

3130 Low intensity repetitive transcranial magnetic stimulation drives structural synaptic plasticity in the young and aged motor cortex.

Tang, A.; Bennett, W.; Bindoff, A.; Collins, J.; Garry, M.; Summers, J.; Hinder, M.; Rodger, J.; Canty, A.

10.1101/2021.03.10.434706 — neuroscience — Posted on 2021-03-11

3131 An algebraic solution for determining overall rotational correlation times from cross-correlated relaxation rates

ROBSON, S. A.; Ziarek, J. J.

10.1101/2021.01.16.426977 — biophysics — Posted on 2021-03-11

3132 Divergence in Population Coding for Space between Dorsal and Ventral CA1

Chockanathan, U.; Padmanabhan, K.

10.1101/2021.03.10.434839 — neuroscience — Posted on 2021-03-11

3133 Odor-evoked Increases in Spiking Variability in the Olfactory Bulb

Ly, C.; Barreiro, A. K.; Gautam, S. H.; Shew, W. L.

10.1101/2021.03.05.434131 — neuroscience — Posted on 2021-03-11

3134 The Memory for Latent Representations: An Account of Working Memory that Builds on Visual Knowledge for Efficient and Detailed Visual Representations

Hedayati, S.; O'Donnell, R.; Wyble, B.

10.1101/2021.02.07.430171 — neuroscience — Posted on 2021-03-11

3135 Newfound coding potential of transcripts unveils missing members of human protein communities

Leblanc, S.; Brunet, M. A.; Jacques, J.-F.; Lekehal, A. M.; Duclos, A.; Tremblay, A.; Bruggeman-Gascon, A.; Samandi, S.; Brunelle, M.; Cohen, A. A.; Scott, M. S.; Roucou, X.

10.1101/2020.12.02.406710 — systems biology — Posted on 2021-03-11

3136 Milk-Way Algorithm applied in Imbalanced Dataset

Leite, C. F. V.; Dos Santos, M. A.

10.1101/2021.02.22.432316 — bioinformatics — Posted on 2021-03-11

3137 how are we stranded here: Quick determination of RNA-Seq strandedness

Signal, B.; Kahlke, T.

10.1101/2021.03.10.434861 — bioinformatics — Posted on 2021-03-11

3138 Single-cell transcriptome reveals a testis-specific expression profile of TCEA in human spermatogenesis

Pramoj Na Ayutthaya, P.; Pankaew, S.

10.1101/2021.03.10.434830 — bioinformatics — Posted on 2021-03-11

3139 Normalization and De-noising of Single-cell Hi-C Data with BandNorm and 3DVI

Zheng, Y.; Shen, S.; Keles, S.

10.1101/2021.03.10.434870 — bioinformatics — Posted on 2021-03-11

3140 Dynamic Detection and Reversal of Myocardial Ischemia Using an Artificially Intelligent Bioelectronic Medicine

Ganzer, P. D.; Loeian, M. S.; Roof, S. R.; Teng, B.; Lin, L.; Friedenberg, D. A.; Baumgart, I. W.; Meyers, E. C.; Chun, K. S.; Rich, A.; Muir, W. W.; Weber, D. J.; Hamlin, R. L.

10.1101/2020.12.30.424900 — bioengineering — Posted on 2021-03-11

3141 Stress-induced tyrosine phosphorylation of RtcB modulates IRE1 activity and signaling outputs.

Papaioannou, A.; Centonze, F. G.; Metais, A.; Maurel, M.; Negroni, L.; Gonzales-Quiroz, M.; Zare Golchesmeh, E.; Blondel, A.; Koong, A. C.; Hetz, C.; Pedeux, R.; Tremblay, M. L.; Eriksson, L. A.; chevet, e.

10.1101/2020.03.02.972950 — biochemistry — Posted on 2021-03-11

3142 Confirmation bias optimizes reward learning

Tarantola, T.; Folke, T.; Boldt, A.; Perez, O. D.; De Martino, B.

10.1101/2021.02.27.433214 — animal behavior and cognition — Posted on 2021-03-11

3143 A novel approach to the detection of unusual mitochondrial protein change suggests hypometabolism of ancestral simians

Akpinar, B. A.; Sharma, V.; Dunn, C. D.

10.1101/2021.03.10.434614 — evolutionary biology — Posted on 2021-03-11

3144 Winter rye cover cropping changes squash (Cucurbita pepo) phyllosphere microbiota and reduces Pseudomonas syringae symptoms

Maglione, R.; Ciotola, M.; Cadieux, M.; Toussaint, V.; Laforest, M.; Kembel, S.

10.1101/2021.03.10.434846 — ecology — Posted on 2021-03-11

3145 Integrin α6 upregulation in nucleus pulposus cell under high oxygen tension attenuates intervertebral disc degeneration

Xu, Z.; Zheng, J.; Zhang, Y.; Wu, H.; Sun, B.; Zhang, K.; Wang, J.; Zang, F.; Zhang, X.; Guo, L.; Wu, X.

10.1101/2021.03.10.434904 — cell biology — Posted on 2021-03-11

3146 A PX-BAR protein Mvp1/SNX8 and a dynamin-like GTPase Vps1 drive endosomal recycling

Suzuki, S.; Oishi, A.; Nikulin, N.; Jorgensen, J. R.; Baile, M. G.; Emr, S. D.

10.1101/2021.03.11.434991 — cell biology — Posted on 2021-03-11

3147 Reproducible microbial community dynamics of two drinking water systems treating similar source waters.

Potgieter, S. C.; Dai, Z.; Havenga, M.; Vosloo, S.; Sigudu, M.; Pinto, A. J.; Venter, S. N.

10.1101/678920 — microbiology — Posted on 2021-03-11

3148 ChAdOx1 nCoV-19 (AZD1222) protects against SARS-CoV-2 B.1.351 and B.1.1.7

10.1101/2021.03.11.435000 — microbiology — Posted on 2021-03-11

3149 Regulatory B cells (Bregs) inhibit osteoclastogenesis and prevent bone loss in osteoporotic mice model

Sapra, L.; Bhardwaj, A.; Mishra, P. K.; Verma, B.; Srivastava, R. K.

10.1101/2021.03.10.434751 — immunology — Posted on 2021-03-11

3150 Intracellular sterol sensing controls intestinal B cell differentiation

Trindade, B. C.; Ceglia, S.; Berthelette, A.; Raso, F.; Howley, K.; Muppidi, J. R.; Reboldi, A.

10.1101/2020.11.03.367177 — immunology — Posted on 2021-03-11

3151 Gallic Acid, a Methyl 3,4-Dihydroxybenzoate Derivative, Induces Neural Stem Cells to Differentiate and Proliferate

Jiang, J.; Liu, W.; Hai, J.; Luo, Y.; Chen, K.; Xin, Y.; Pan, J.; Hu, Y.; Gao, Q.; Xiao, F.; Luo, H.

10.1101/2021.03.01.433474 — neuroscience — Posted on 2021-03-11

3152 Inferring brain-wide interactions using data-constrained recurrent neural network models

Perich, M. G.; Arlt, C.; Soares, S.; Young, M. E.; Mosher, C. P.; Minxha, J.; Carter, E.; Rutishauser, U.; Rudebeck, P. H.; Harvey, C. D.; Rajan, K.

10.1101/2020.12.18.423348 — neuroscience — Posted on 2021-03-11

3153 iEC7871 Quercus suber model: the first multi-tissue diel cycle genome-scale metabolic model of a woody tree

Cunha, E.; Silva, M.; Chaves, I.; Demirci, H.; Lagoa, D.; Lima, D.; Rocha, M.; Rocha, I.; Dias, O.

10.1101/2021.03.09.434537 — systems biology — Posted on 2021-03-11

3154 Biofoundry-assisted expression and characterisation of plant proteins

Dudley, Q. M.; Cai, Y.; Kallam, K.; Debreyne, H.; Carrasco-Lopez, J. A.; Patron, N. J.

10.1101/2021.03.11.434954 — synthetic biology — Posted on 2021-03-11

3155 Spatial and Temporal Localization of SPIRRIG and WAVE/SCAR Reveal Roles for These Proteins in Actin-Mediated Root Hair Development

Chin, S.; Kwon, T.; Khan, B. R.; Sparks, J. A.; Mallery, E. L.; Szymanski, D. B.; Blancaflor, E. B.

10.1101/2020.11.13.381848 — plant biology — Posted on 2021-03-11

3156 The Induction of Pyrenoid Synthesis by Hyperoxia and its Implications for the Natural Diversity of Photosynthetic Responses in Chlamydomonas

Neofotis, P.; Temple, J.; Tessmer, O.; Bibik, J.; Norris, N.; Poliner, E.; Lucker, B.; Wijetilleke, S.; Withrow, A.; Sears, B.; Mogos, G.; Frame, M.; Hall, D.; Weissman, J.; Kramer, D. M.

10.1101/2021.03.10.434646 — plant biology — Posted on 2021-03-11

3157 Gene expression shapes the patterns of parallel evolution of herbicide resistance in the agricultural weed Monochoria vaginalis

Tanigaki, S.; Uchino, A.; Okawa, S.; Miura, C.; Hamamura, K.; Matsuo, M.; Yoshino, N.; Ueno, N.; Toyama, Y.; Fukumi, N.; Kijima, E.; Masuda, T.; Shimono, Y.; Tominaga, T.; Iwakami, S.

10.1101/2021.03.10.434542 — plant biology — Posted on 2021-03-11

3158 The desert green algae Chlorella ohadii thrives at excessively high light intensities by exceptionally enhancing the mechanisms that protect photosynthesis from photoinhibition

Levin, G.; Kulikovsky, S.; Liveanu, V.; Eichenbaum, B.; Meir, A.; Isaacson, T.; Tadmor, Y.; Adir, N.; Schuster, G.

10.1101/2021.02.08.430232 — plant biology — Posted on 2021-03-11

3159 VAL genes regulate vegetative phase change via miR156-dependent and independent mechanisms

Fouracre, J. P.; He, J.; Chen, V. J.; Sidoli, S.; Poethig, R. S.

10.1101/2021.02.23.432516 — plant biology — Posted on 2021-03-11

3160 Immunity Depletion, Telomere Imbalance, and Cancer-associated Metabolism Pathway Aberrations in Intestinal Mucosa upon Caloric Restriction

Maestri, E.; Duszka, K.; Kuznetsov, V. A.

10.1101/2021.03.10.433216 — cancer biology — Posted on 2021-03-11

3161 A breast cancer patient-derived xenograft and organoid platform for drug discovery and precision oncology

Guillen, K. P.; Fujita, M.; Butterfield, A. J.; Scherer, S. D.; Bailey, M. H.; Chu, Z.; DeRose, Y. S.; Zhao, L.; Cortes-Sanchez, E.; Yang, C.-H.; Toner, J.; Wang, G.; Qiao, Y.; Huang, X.; Greenland, J. A.; Vahrenkamp, J. M.; Lum, D. H.; Factor, R. E.; Nelson, E. W.; Matsen, C. B.; Poretta, J. M.; Rosenthal, R.; Beck, A. C.; Buys, S. S.; Vaklavas, C.; Ward, J. H.; Jensen, R. L.; Jones, K. B.; Li, Z.; Oesterreich, S.; Dobrolecki, L. E.; Pathi, S. S.; Woo, X. Y.; Berrett, K. C.; Wadsworth, M. E.; Chuang, J. H.; Lewis, M. T.; Marth, G. T.; Gertz, J.; Varley, K. E.; Welm, B. E.; Welm, A. L.

10.1101/2021.02.28.433268 — cancer biology — Posted on 2021-03-11

3162 Acute myeloid leukemia cells are targeted by the naturally occurring CXCR4 antagonist EPI-X4

Kaiser, L. M.; Harms, M.; Sauter, D.; Rawat, V. P. S.; Glitscher, M.; Hildt, E.; Doehner, K.; Doehner, H.; Muench, J.; Buske, C.

10.1101/2021.03.11.434944 — cancer biology — Posted on 2021-03-11

3163 A Tunable, Simplified Model for Biological Latch Mediated Spring Actuated Systems

Cook, A.; Pandhigunta, K.; Acevedo, M. A.; Walker, A.; Didcock, R. L.; Castro, J. T.; Acharya, R.; Bhamla, M. S.; Anderson, P. S. L.; Ilton, M.

10.1101/2020.12.02.408740 — biophysics — Posted on 2021-03-11

3164 Facilitated Dissociation of Nucleoid Associated Proteins from DNA in the Bacterial Confinement

Kosar, Z.; Attar, A. G.; Erbas, A.

10.1101/2021.03.11.434965 — biophysics — Posted on 2021-03-11

3165 A deep learning algorithm to translate and classify cardiac electrophysiology: From induced pluripotent stem cell-derived cardiomyocytes to adult cardiac cells

Aghasafari, P.; Yang, P.-C.; Kernik, D. C.; Sakamoto, K.; Kanda, Y.; Kurokawa, J.; Vorobyov, I.; Clancy, C. E.

10.1101/2020.09.28.317461 — bioinformatics — Posted on 2021-03-11

3166 A small fraction of progenitors differentiate into mature adipocytes due to constraints on the cell structure change

Ahmed, M.; Lai, T. H.; Kim, D. R.

10.1101/2021.03.10.434887 — bioinformatics — Posted on 2021-03-11

3167 A Comparative Analysis of Novel Deep Learning Models and Ensemble Learning Models to Predict the Allergenicity of Food Allergens

Wang, L.; Niu, D.; Zhao, X.; Wang, X.; Hao, M.; Che, H.

10.1101/2021.03.10.434710 — bioinformatics — Posted on 2021-03-11

3168 Computational analysis of vertebrate myoglobins reveals aggregation resistance in aquatic birds and higher surface hydrophobicity in fish

Rizvi, S. M.; Zheng, W.; Zhang, C.; Zhang, Y.

10.1101/2021.02.26.433090 — bioinformatics — Posted on 2021-03-11

3169 Coordination of -1 Programmed Ribosomal Frameshifting by Transcript and Nascent Chain Features Revealed by Deep Mutational Scanning

Carmody, P. J.; Zimmer, M. H.; Kuntz, C. P.; Harrington, H. R.; Duckworth, K. E.; Penn, W. D.; Mukhopahyay, S.; Miller, T. F.; Schlebach, J. P.

10.1101/2021.03.11.435011 — biochemistry — Posted on 2021-03-11

3170 Functional characterization of a DNA-dependent AAA ATPase in SimranZ1, a F cluster mycobacteriophage

Das, R.; Bajpai, U.

10.1101/2021.03.11.434926 — biochemistry — Posted on 2021-03-11

3171 A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing

Fan, H.; Guo, Y.; Wang, G. G.

10.1101/2021.03.11.435004 — biochemistry — Posted on 2021-03-11

3172 Distinct foraging strategies generated by single-action behavioural flexibility

Quach, K. T.; Chalasani, S. H.

10.1101/2021.03.09.434602 — animal behavior and cognition — Posted on 2021-03-11

3173 Emerging variants of concern in SARS-CoV-2 membrane protein: a highly conserved target with potential pathological and therapeutic implications

Shen, L.; Dien Bard, J.; Triche, T. J.; Judkins, A. R.; Biegel, J. A.; Gai, X.

10.1101/2021.03.11.434758 — genomics — Posted on 2021-03-11

3174 Characterization and Heterotic Grouping of Traditional Assam rice (Oryza sativa L.)

Kumar, P.; Sarma, D.

10.1101/2021.03.10.434899 — genomics — Posted on 2021-03-11

3175 Permissive epigenetic landscape facilitates distinct transcriptional signatures of activating transcription factor 6 in the liver

Ramdas Nair, A.; Lakhiani, P.; Zhang, C.; Macchi, F.; Sadler, K. C.

10.1101/2021.03.10.434889 — genomics — Posted on 2021-03-11

3176 Reversion is most likely under high mutation supply, when compensatory mutations don't fully restore fitness costs

Pennings, P. S.; Ogbunugafor, C. B.; Hershberg, R.

10.1101/2020.12.28.424568 — evolutionary biology — Posted on 2021-03-11

3177 One pair of motor neurons provokes early spontaneous motor behavior through periodic bursting in the chordate ascidian embryo

Akahoshi, T.; Oonuma, K.; Murakami, M.; Horie, T.; Kusakabe, T. G.; Oka, K.; Hotta, K.

10.1101/2021.03.10.434256 — developmental biology — Posted on 2021-03-11

3178 A quantitative landscape of cell fate transitions identifies principles of cellular decision-making

Saez, M.; Blassberg, R.; Camacho-Aguilar, E.; Siggia, E. D.; Rand, D. A.; Briscoe, J.

10.1101/2021.03.11.434982 — developmental biology — Posted on 2021-03-11

3179 Human iPSC-derived cerebral organoids model features of Leigh Syndrome and reveal abnormal corticogenesis

Romero-Morales, A. I.; Rastogi, A.; Robertson, G. L.; Rasmussen, M. L.; Temuri, H.; Chakrabarty, R. P.; McElroy, G. S.; Hsu, L.; Almonacid, P. M.; Millis, B. A.; Chandel, N. S.; Cartailler, J.-P.; Gama, V.

10.1101/2020.04.21.054361 — cell biology — Posted on 2021-03-11

3180 Differential serotonin uptake mechanisms at the human maternal-fetal interface

Bakovic, P.; Kesic, M.; Horvaticek, M.; George, M.; Peric, M.; Beceheli, I.; Cicin-Sain, L.; Desoye, G.; Wadsack, C.; Panzenboeck, U.; Stefulj, J.

10.1101/2021.01.07.425725 — cell biology — Posted on 2021-03-11

3181 Co-chaperone involvement in knob biogenesis implicates host-derived chaperones in malaria virulence

Diehl, M.; Weber, S.; Cyrklaff, M.; Sanchez, C. P.; Beretta, C. A.; Roling, L.; Simon, C. S.; Guizetti, J.; Mayer, M. P.; Przyborski, J. M.

10.1101/2021.03.11.434953 — cell biology — Posted on 2021-03-11

3182 A dynamic equilibrium between TTP and CPEB4 controls mRNA stability and inflammation resolution

Suner, C.; Sibilio, A.; Martín, J.; Castellazi, C. L.; Reina, O.; Dotu, I.; Caballe, A.; Rivas, E.; Calderone, V.; Diez, J.; Nebreda, A. R.; Mendez, R.

10.1101/2021.03.11.434803 — molecular biology — Posted on 2021-03-11

3183 Rapid characterization of complex genomic regions using Cas9 enrichment and Nanopore sequencing

Bruijnesteijn, J.; van der Wiel, M.; de Groot, N. G.; Bontrop, R. E.

10.1101/2021.03.11.434935 — molecular biology — Posted on 2021-03-11

3184 Release, rescue and recycling: termination of translation in mammalian mitochondria

Kummer, E.; Schubert, K.; Schoenhut, T.; Scaiola, A.; Ban, N.

10.1101/2021.03.10.434893 — molecular biology — Posted on 2021-03-11

3185 Phodopus roborovskii SH101 as a systemic infection model of SARS-CoV-2

Zhai, C.; Wang, M.; Chung, H.-J.; Hassan, M. M.; Lee, S.; Kim, H.-J.; Hong, S.-T.

10.1101/2021.03.10.434891 — microbiology — Posted on 2021-03-11

3186 In vitro and in vivo preclinical studies predict REGEN-COV protection against emergence of viral escape in humans

10.1101/2021.03.10.434834 — microbiology — Posted on 2021-03-11

3187 Membrane-Tethered Mucin 1 is Stimulated by Interferon in Multiple Cell Types and Antagonizes Influenza A Virus Infection in Human Airway Epithelium

Iverson, E.; Griswold, K.; Song, D.; Gagliardi, T. B.; Hamidzadeh, K.; Kesimer, M.; Sinha, S.; Perry, M.; Duncan, G. A.; Scull, M. A.

10.1101/2021.03.11.434997 — microbiology — Posted on 2021-03-11

3188 Bacterial filamentation drives colony chirality

Aranda-Díaz, A.; Rodrigues, C.; Grote, A.; Sun, J.; Schreck, C.; Hallatschek, O.; Souslov, A.; Möbius, W.; Huang, K.

10.1101/2021.03.11.434908 — microbiology — Posted on 2021-03-11

3189 Low ozone concentration and negative ions for rapid SARS-CoV-2 inactivation

De Forni, D.; Poddesu, B.; Cugia, G.; Gallizia, G.; La Licata, M.; Lisziewicz, J.; Chafouleas, J. G.; Lori, F.

10.1101/2021.03.11.434968 — microbiology — Posted on 2021-03-11

3190 Alphaproteobacteria facilitate Trichodesmium community trimethylamine utilization

Conover, A. E.; Morando, M.; Zhao, Y.; Semones, J.; Hutchins, D. A.; Webb, E. A.

10.1101/2021.03.10.434842 — microbiology — Posted on 2021-03-11

3191 Inferring large-scale structural connectivity from local activity in a model of the mouse large-scale cortical network

Nunes, R. V.; Reyes, M. B.; Mejias, J. F.; de Camargo, R. Y.

10.1101/2021.01.28.428656 — neuroscience — Posted on 2021-03-11

3192 Rats spontaneously perceive global motion direction of drifting plaids

Matteucci, G.; Zattera, B.; Bellacosa Marotti, R.; Zoccolan, D.

10.1101/2021.02.24.432732 — neuroscience — Posted on 2021-03-11

3193 Beyond Turing: Far-from-equilibrium patterns and mechano-chemical feedback

Veerman, F.; Mercker, M.; Marciniak-Czochra, A.

10.1101/2021.03.10.434636 — systems biology — Posted on 2021-03-11

3194 Exploring the understudied human kinome for research and therapeutic opportunities

Moret, N.; Liu, C.; Gyori, B. M.; Bachman, J. A.; Steppi, A.; Hug, C.; Taujale, R.; Huang, L.-C.; Berginski, M.; Gomez, S. M.; Kannan, N.; Sorger, P.

10.1101/2020.04.02.022277 — systems biology — Posted on 2021-03-11

3195 ZIKV disrupts fetal outcome, placental ultrastructure and drug transporter expression in mice

Andrade, C. B. V.; Monteiro, V. R. S.; Coelho, S. V. A.; Gomes, H. R.; Sousa, R. P. C.; Nascimento, V. M. O.; Bloise, F. F.; Matthews, S. G.; Bloise, E.; Arruda, L. B.; Ortiga-Carvalho, T. M.

10.1101/2020.12.17.423218 — physiology — Posted on 2021-03-11

3196 Bromodomain and Extraterminal Protein Inhibitor, Apabetalone (RVX-208), Reduces ACE2 Expression and Attenuates SARS-CoV-2 Infection in vitro

Gilham, D.; Smith, A. L.; Fu, L.; Moore, D. Y.; Muralidharan, A.; Reid, S. P. M.; Stotz, S. C.; Johansson, J. O.; Sweeney, M.; Wong, N. C.; Kulikowski, E.; El-Gamal, D.

10.1101/2021.03.10.432949 — pharmacology and toxicology — Posted on 2021-03-11

3197 The fast-slow continuum is not the end-game of life history evolution, human or otherwise

Salguero-Gomez, R.

10.1101/2021.03.09.434595 — evolutionary biology — Posted on 2021-03-11

3198 Female fruitflies use gustatory cues to exhibit reproductive plasticity in response to the social environment

Fowler, E. K.; Leigh, S.; Rostant, W. G.; Thomas, A.; Bretman, A.; Chapman, T.

10.1101/2021.03.10.434778 — evolutionary biology — Posted on 2021-03-11

3199 Behavior emerges from unstructured muscle activity in response to neuromodulation

Elliott, A.; Berndt, A.; Houpert, M.; Roy, S.; Scott, R. L.; Chow, C. C.; Shroff, H.; White, B.

10.1101/2021.03.10.434785 — neuroscience — Posted on 2021-03-11

3200 The optimal spatial arrangement of ON and OFF receptive fields

Jun, N. Y.; Field, G. D.; Pearson, J. M.

10.1101/2021.03.10.434612 — neuroscience — Posted on 2021-03-11

3201 Insulin-stimulated adiponectin secretion in pregnancy is mediated by inhibition of adiponectin ubiquitination and degradation and is impaired in obesity

Aye, I. L. M. H.; Rosario, F. J.; Kramer, A.; Kristiansen, O.; Michelsen, T. M.; Powell, T. L.; Jansson, T.

10.1101/2021.03.10.432857 — physiology — Posted on 2021-03-11

3202 In vitro profiling of orphan G protein coupled receptor (GPCR) constitutive activity

Watkins, L. R.; Orlandi, C.

10.1101/2021.03.10.434788 — pharmacology and toxicology — Posted on 2021-03-11

3203 Single-Cell Spatial Proteomics Analyses of Head and Neck Squamous Cell Carcinoma Reveal Tumor Heterogeneity and Immune Architectures Associated with Clinical Outcome

Blise, K. E.; Sivagnanam, S.; Banik, G. L.; Coussens, L. M.; Goecks, J.

10.1101/2021.03.10.434649 — cancer biology — Posted on 2021-03-11

3204 SeqWho: Reliable, rapid determination of sequence file identity using k-mer frequencies

Bennett, C.; Thornton, M.; Park, C.; Henry, G.; Zhang, Y.; Malladi, V. S.; Kim, D.

10.1101/2021.03.10.434827 — bioinformatics — Posted on 2021-03-11

3205 The Genetic Basis of Differential Autodiploidization in Evolving Yeast Populations

Tung, S.; Bakerlee, C. W.; Phillips, A. M.; Nguyen Ba, A. N.; Desai, M. M.

10.1101/2021.03.10.434832 — evolutionary biology — Posted on 2021-03-11

3206 Seasonal dynamics and repeatability of gastrointestinal parasite burdens in wild Soay sheep

Sweeny, A. R.; Corripio-Miyar, Y.; Bal, X.; Hayward, A. D.; Pilkington, J. G.; Pemberton, J. M.; McNeilly, T. N.; Nussey, D. H.; Kenyon, F.

10.1101/2021.03.10.434794 — ecology — Posted on 2021-03-11

3207 The stem loop 2 motif is a site of vulnerability for SARS-CoV-2

Lulla, V.; Wandel, M. P.; Bandyra, K. J.; Dendooven, T.; Yang, X.; Doyle, N.; Oerum, S.; O'Rourke, S.; Randow, F.; Maier, H. J.; Scott, W.; Ding, Y.; Firth, A.; Bloznelyte, K.; Luisi, B.; Ulferts, R.; Wu, M.; Beale, R.

10.1101/2020.09.18.304139 — molecular biology — Posted on 2021-03-11

3208 Telencephalic outputs from the medial entorhinal cortex are copied directly to the hippocampus

Tsoi, S. Y.; Öncül, M.; Svahn, E.; Robertson, M.; Bogdanowicz, Z.; McClure, C.; Sürmeli, G.

10.1101/2021.03.10.434566 — neuroscience — Posted on 2021-03-11

3209 Gamma-irradiated SARS-CoV-2 vaccine candidate, OZG-38.61.3, confers protection from SARS-CoV-2 challenge in human ACEII-transgenic mice

Turan, R. D.; Tastan, C.; Dilek Kancagi, D.; Yurtsever, B.; Sir Karakus, G.; Ozer, S.; Abanuz, S.; Cakirsoy, D.; Tumentemur, G.; Demir, S.; Seyis, U.; Kuzay, R.; Elek, M.; Kocaoglu, M. E.; Ertop, G.; Arbak, S.; Acikel Elmas, M.; Hemsinlioglu, C.; Hatirnaz Ng, O.; Akyoney, S.; Sahin, I.; Kayhan, C. K.; Tokat, F.; Akpinar, G.; Kasap, M.; Kocagoz, A. S.; Ozbek, U.; Telci, D.; Sahin, F.; Yalcin, K.; Ratip, S.; Ince, U.; Ovali, E.

10.1101/2020.10.28.356667 — immunology — Posted on 2021-03-11

3210 SARS-CoV-2 501Y.V2 (B.1.351) elicits cross-reactive neutralizing antibodies

Moyo-Gwete, T.; Madzivhandila, M.; Makhado, Z.; Ayres, F.; Mhlanga, D.; Oosthuysen, B.; Lambson, B.; Kgagudi, P.; Tegally, H.; Iranzadeh, A.; Doolabh, D.; Tyers, L.; Chinhoyi, L.; Mennen, M.; Skelem, S.; Marais, G.; Wibmer, C. K.; Bhiman, J.; Ueckermann, V.; Rossouw, T.; Boswell, M.; de Oliveira, T.; Williamson, C.; Burgers, W.; Ntusi, N.; Morris, L.; Moore, P.

10.1101/2021.03.06.434193 — immunology — Posted on 2021-03-11

3211 Neural oscillations track natural but not artificial fast speech: Novel insights from speech-brain coupling using MEG

Hincapie Casas, A. S.; Lajnef, T.; Pascarella, A.; Guiraud, H.; Laaksonen, H.; Bayle, D.; Jerbi, K.; Boulenger, V.

10.1101/2020.10.20.344895 — neuroscience — Posted on 2021-03-11

3212 NMR unveils an N-terminal interaction interface on acetylated-α-synuclein monomers for recruitment to fibrils

Yang, X.; Wang, B.; Hoop, C. L.; Williams, J. K.; Baum, J.

10.1101/2020.08.17.254508 — biophysics — Posted on 2021-03-11

3213 Dual RNA modulation of protein mobility and stability within phase-separated condensates

Tejedor, A. R.; Garaizar, A.; Ramirez, J.; Espinosa, J. R.

10.1101/2021.03.05.434111 — biophysics — Posted on 2021-03-11

3214 An Evolutionary Process Without Variation and Selection

Gabora, L.; Steel, M.

10.1101/2020.08.30.274407 — evolutionary biology — Posted on 2021-03-11

3215 Tiled-ClickSeq for targeted sequencing of complete coronavirus genomes with simultaneous capture of RNA recombination and minority variants

Routh, A. L.; Jaworski, E.; Langsjoen, R. M.; Judy, B.; Newman, P.; Zhou, Y.; Swetnam, D.; Miller, A. L.; Plante, J. A.; Plante, K. S.; Dong, J.; Ren, P.; Ksiazek, T.; Menachery, V. D.; Weaver, S.

10.1101/2021.03.10.434828 — molecular biology — Posted on 2021-03-11

3216 Identification of essential genes for Escherichia coli aryl polyene biosynthesis and function in biofilm formation

Johnston, I.; Osborn, L. J.; Markley, R. L.; McManus, E. A.; Kadam, A.; Schultz, K. B.; Nagajothi, N.; Ahern, P. A.; Brown, J. M.; Claesen, J.

10.1101/2020.04.22.055939 — microbiology — Posted on 2021-03-11

3217 Intestinal infection results in impaired lung innate immunity to secondary respiratory infection.

Trivedi, S.; Grossmann, A. H.; Jensen, O.; Cody, M. J.; Wahlig, T. A.; Serpa, P. H.; Langelier, C.; Warren, K. J.; Yost, C. C.; Leung, D. T.

10.1101/2020.08.03.235457 — immunology — Posted on 2021-03-11

3218 Global organization of neuronal activity only requires unstructured local connectivity

Dahmen, D.; Layer, M.; Deutz, L.; Dabrowska, P. A.; Voges, N.; von Papen, M.; Brochier, T.; Riehle, A.; Diesmann, M.; Grün, S.; Helias, M.

10.1101/2020.07.15.205013 — neuroscience — Posted on 2021-03-11

3219 Effect of Handedness on Learned Controllers and Sensorimotor Noise During Trajectory-Tracking

Yamagami, M.; Peterson, L. N.; Howell, D. B.; Roth, E.; Burden, S. A.

10.1101/2020.08.01.232454 — neuroscience — Posted on 2021-03-11

3220 Rest is Required to Learn an Appetitively-Reinforced Operant Task in Drosophila

Wiggin, T. D.; Hsiao, Y.-Y.; Liu, J. B.; Huber, R.; Griffith, L. C.

10.1101/2020.08.28.272047 — neuroscience — Posted on 2021-03-11

3221 Circadian fluctuations in glucocorticoid level predict perceptual discrimination sensitivity

Obleser, J.; Kreitewolf, J.; Vielhauer, R.; Lindner, F.; David, C.; Oster, H.; Tune, S.

10.1101/2020.10.07.330282 — neuroscience — Posted on 2021-03-11

3222 Novel inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives

Amporndanai, K.; Meng, X.; Yang, H.; Liu, Z.-J.; Zhang, L.; Zhao, Y.; Hasnain, S.; O'Neill, P.; Rao, Z.; Jin, Z.; Shang, W.

10.1101/2021.03.11.434764 — biophysics — Posted on 2021-03-11

3223 Segmentation-less, automated vascular vectorization robustly extracts neurovascular network statistics from in vivo two-photon images

Mihelic, S.; Sikora, W.; Hassan, A.; Williamson, M.; Jones, T.; Dunn, A.

10.1101/2020.06.15.151076 — bioengineering — Posted on 2021-03-11

3224 ATP-binding cassette protein ABCF1 couples transcription and genome surveillance in embryonic stem cells through low complexity domain

Choi, E.-B.; Vodnala, M.; Zerbato, M.; Wang, J.; Ho, J. J.; Inouye, C.; Fong, Y. W.

10.1101/2020.05.28.122184 — biochemistry — Posted on 2021-03-11

3225 Macroevolutionary Stability Predicts Interaction Patterns of Species in Seed Dispersal Networks

Burin, G.; Guimaraes, P. R.; Bosisio Quental, T.

10.1101/2020.04.15.042754 — evolutionary biology — Posted on 2021-03-11

3226 SARS-CoV-2 comprehensive receptor profiling: mechanistic insight to drive new therapeutic strategies

Brockbank, S. M.; Faba-Rodriguez, R.; Rosenbrier Ribeiro, L.; Geh, C.; Thomas, H.; Delight, J.; Coverley, L.; Abbott, W. M.; Soden, J.; Freeth, J.

10.1101/2021.03.11.434937 — cell biology — Posted on 2021-03-11

3227 Antibody responses to SARS-CoV-2 mRNA vaccines are detectable in saliva

Ketas, T. J.; Chaturbhuj, D.; Cruz Portillo, V.; Francomano, E.; Golden, E.; Chandrasekhar, S.; Debnath, G.; Diaz Tapia, R.; Yasmeen, A.; Leconet, W.; Zhao, Z.; Brouwer, P. J. M.; Cushing, M. M.; Sanders, R.; Cupo, A.; Klasse, P. J.; Formenti, S. C.; Moore, J. P.

10.1101/2021.03.11.434841 — microbiology — Posted on 2021-03-11

3228 ACE2-lentiviral transduction enables mouse SARS-CoV-2 infection and mapping of receptor interactions

Rawle, D. J.; Le, T. T.; Dumenil, T.; Yan, K.; Tang, B.; Bishop, C.; Suhrbier, A.

10.1101/2021.02.09.430547 — microbiology — Posted on 2021-03-11

3229 Nelfinavir markedly improves lung pathology in SARS-CoV-2-infected Syrian hamsters despite lack of an antiviral effect

Foo, C. S.; Abdelnabi, R.; Kaptein, S. J. F.; Zhang, X.; ter Horst, S.; Mols, R.; Delang, L.; Rocha-Pereira, J.; Coelmont, L.; Leyssen, P.; Dallmeier, K.; Vergote, V.; Heylen, E.; Vangeel, L.; Chatterjee, A. K.; Annaert, P.; Augustijns, P.; De Jonghe, S.; Jochmans, D.; Weynand, B.; Neyts, J.

10.1101/2021.02.01.429108 — microbiology — Posted on 2021-03-11

3230 Acquisition of the L452R mutation in the ACE2-binding interface of Spike protein triggers recent massive expansion of SARS-Cov-2 variants

Tchesnokova, V.; Kulakesara, H.; Larson, L.; Bowers, V.; Rechkina, E.; Kisiela, D.; Sledneva, Y.; Choudhury, D.; Maslova, I.; Deng, K.; Kutumbaka, K.; Geng, H.; Fowler, C.; Ralston, J. D.; Greene, D.; Samadpour, M.; Sokurenko, E. V.

10.1101/2021.02.22.432189 — microbiology — Posted on 2021-03-11

3231 A tandem-repeat dimeric RBD protein-based COVID-19 vaccine ZF2001 protects mice and nonhuman primates

An, Y.; Li, S.; Jin, X.; Han, J.-B.; Xu, K.; Xu, S.; Han, Y.; Liu, C.; Zheng, T.; Liu, M.; Yang, M.; Song, T.-z.; Huang, B.; Zhao, L.; Wang, W.; A, R.; Cheng, Y.; Wu, C.; Huang, E.; Yang, S.; Wang, G.; Bi, Y.; Ke, C.; Tan, W.; Yan, J.; Zheng, Y.-T.; Dai, L.; Gao, G. F.

10.1101/2021.03.11.434928 — immunology — Posted on 2021-03-11

3232 Aβ promotes amyloidogenic processing of APP through a Go/Gβγ signaling

Antonino, M.; Marmo, P.; Freites, C. L.; Quassollo, G. E.; Sanchez, M. F.; Lorenzo, A.; Bignante, E. A.

10.1101/2021.03.10.434768 — neuroscience — Posted on 2021-03-11

3233 Memory for Individual Items is Related to Non-Reinforced Preference Change

Botvinik-Nezer, R.; Bakkour, A.; Salomon, T.; Shohamy, D.; Schonberg, T.

10.1101/621292 — neuroscience — Posted on 2021-03-11

3234 Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation

Deganutti, G.; Liang, Y.-L.; Zhang, X.; Khoshouei, M.; Clydesdale, L.; Belousoff, M. J.; Venugopal, H.; Truong, T. T.; Glukhova, A.; Keller, A. N.; Gregory, K. J.; Leach, K.; Christopoulos, A.; Danev, R.; Reynolds, C. A.; Zhao, P.; Sexton, P. M.; Wootten, D. M.

10.1101/2021.03.10.434902 — biochemistry — Posted on 2021-03-11

3235 Distinct profiles of spatio-temporal brain dynamics along symptoms dimensions in autism

Mullier, E.; Kojovic, N.; Denervaud, S.; Vohryzek, J.; Hagmann, P.; Schaer, M.

10.1101/2021.03.11.434353 — neuroscience — Posted on 2021-03-11

3236 An updated genome-scale metabolic network reconstruction of Pseudomonas aeruginosa PA14 to characterize mucin-driven shifts in bacterial metabolism

Payne, D. D.; Renz, A.; Dunphy, L. J.; Lewis, T.; Draeger, A.; Papin, J. A.

10.1101/2021.03.10.434463 — systems biology — Posted on 2021-03-11

3237 A general model of multivalent binding with ligands of heterotypic subunits and multiple surface receptors

Tan, Z. C.; Meyer, A. S.

10.1101/2021.03.10.434776 — systems biology — Posted on 2021-03-11

3238 Stability of DNA methylation and chromatin accessibility in structurally diverse maize genomes

Noshay, J. M.; Liang, Z.; Zhou, P.; Crisp, P. A.; Marand, A. P.; Hirsch, C. N.; Schmitz, R. J.; Springer, N.

10.1101/2021.03.10.434810 — plant biology — Posted on 2021-03-11

3239 The level of synovial human VEGFA, IL-8 and MIP-1α correlate with truncation of lubricin glycans in osteoarthritis

Huang, S.; Thomsson, K. A.; Jin, C.; Ryberg, H.; Das, N.; Struglics, A.; Rolfson, O.; Björkman, L. I.; Eisler, T.; Schimdt, T. A.; Jay, G. D.; Krawetz, R.; Karlsson, N. G.

10.1101/2021.03.11.434779 — pathology — Posted on 2021-03-11

3240 Different issue types have different signal intensity on b=0 images and its implication on intravoxel incoherent motion (IVIM) analysis: examples of liver MRI

Xiao, B.-H.; Wang, Y.-X.

10.1101/2021.03.11.431356 — biophysics — Posted on 2021-03-11

3241 Handling of intracellular K + determines voltage dependence of plasmalemmal monoamine transporter function

Sandtner, W.; Bhat, S.; Niello, M.; Schicker, K.; Pifl, C.; Sitte, H. H.; Freissmuth, M.

10.1101/2021.03.11.434931 — biophysics — Posted on 2021-03-11

3242 PhyloCSF++: A fast and user-friendly implementation of PhyloCSF with annotation tools

Pockrandt, C.; Steinegger, M.; Salzberg, S.

10.1101/2021.03.10.434297 — bioinformatics — Posted on 2021-03-11

3243 TRANSFER ENTROPY BASED CAUSALITY FROM HEAD MOTION TO EYE MOVEMENT

Lv, Z.; Xu, Q.; Schoeffmann, K.; Parkinson, S.

10.1101/2021.03.11.434910 — bioinformatics — Posted on 2021-03-11

3244 Sampling of Structure and Sequence Space of Small Protein Folds

Linsky, T. W.; Noble, K.; Tobin, A.; Crow, R.; Carter, L. P.; Urbauer, J. L.; Baker, D.; Strauch, E.-M.

10.1101/2021.03.10.434454 — bioengineering — Posted on 2021-03-11

3245 Additive and synergistic effects of arbuscular mycorrhizal fungi, insect pollination and nutrient availability in a perennial fruit crop

Chen, K.; Kleijn, D.; Scheper, J.; Fijen, T. P. M.

10.1101/2021.03.11.434774 — ecology — Posted on 2021-03-11

3246 Reconstituting the genus Mycobacterium

Meehan, C. J.; Barco, R.; Loh, Y.-H.; Cogneau, S.; Rigouts, L.

10.1101/2021.03.11.434933 — microbiology — Posted on 2021-03-11

3247 CD36 family members are TCR-independent ligands for CD1 antigen-presentingmolecules

Gherardin, N. A.; Redmond, S. J.; McWilliam, H. E.; Almeida, C. F.; Gourley, K. H.; Seneviratna, R.; Li, S.; De Rose, R.; Nguyen-Robertson, C. V.; Su, S.; Ritchie, M.; Villadangos, J. A.; Moody, D. B.; Pellicci, D. G.; Uldrich, A. P.; Godfrey, D. I.

10.1101/2021.03.10.434884 — immunology — Posted on 2021-03-11

3248 A New Type of Satellite associated with Cassava Mosaic Begomoviruses

Aimone, C. D.; De Leon, L.; Dallas, M. M.; Ndunguru, J.; Ascencio-Ibanez, J. T.; Hanley-Bowdoin, L.

10.1101/2021.03.11.434950 — plant biology — Posted on 2021-03-11

3249 DFT and Raman study of all-trans astaxanthin optical isomers

Yao, G.; Guo, S.; Yu, W.; Muhammad, M.; Liu, J.; Huang, Q.

10.1101/2021.03.11.434912 — biophysics — Posted on 2021-03-11

3250 Structured illumination microscopy with noise-controlled image reconstructions

Smith, C. S.; Slotman, J.; Schermelleh, L.; Chakrova, N.; Hari, S.; Vos, Y.; Hagen, C. W.; Mueller, M.; van Cappellen, W.; Houtsmuller, A.; Hoogenboom, J. P.; Stallinga, S.

10.1101/2021.03.11.434940 — biophysics — Posted on 2021-03-11

3251 GRAMMAR-Lambda: An Extreme Simplification for Genome-wide Mixed Model Association Analysis

Yang, R.; Gao, J.; Song, Y.; Hao, Z.; Xu, P.

10.1101/2021.03.10.434574 — bioinformatics — Posted on 2021-03-11

3252 Efficient Genomic Control for Mixed Model Associationsin Large-scale Population

Hao, Z.; Gao, J.; Song, Y.; Yang, R.; Liu, D.

10.1101/2021.03.10.434745 — bioinformatics — Posted on 2021-03-11

3253 Generalized Hierarchical Mixed Model Association Analysis

Yang, R.; Song, Y.; Hao, Z.; Liu, Z.

10.1101/2021.03.10.434742 — bioinformatics — Posted on 2021-03-11

3254 Genomic heterogeneity affects the response to Daylight Saving Time

Tyler, J.; Fang, Y.; Goldstein, C.; Forger, D. B.; Sen, S.; Burmeister, M.

10.1101/2021.03.10.434637 — genomics — Posted on 2021-03-11

3255 Complex landscapes partially mitigate negative pesticide effects on tropical pollinator communities

Obregon, D.; Guerrero, O. R.; Stashenko, E.; Poveda, K.

10.1101/2021.03.10.434664 — ecology — Posted on 2021-03-11

3256 Pool choice in a vertical landscape: tadpole rearing site flexibility in phytotelm-breeding frogs

Fouilloux, C. A.; Serrano-Rojas, S. J.; Carvajal-Castro, J. D.; Valkonen, J. K.; Gaucher, P.; Fischer, M.-T.; Pasukonis, A.; Rojas, B.

10.1101/2021.03.10.434757 — ecology — Posted on 2021-03-11

3257 Beyond residence time: quantifying factors that drive the spatially explicit filtration services of a 'pristine' oyster population

Gray, M. W.; Pinton, D.; Canestrelli, A.; Marcum, P.; Dix, N.; Kimbro, D.; Grizzle, R.

10.1101/2021.03.10.434772 — ecology — Posted on 2021-03-11

3258 The zebrafish presomitic mesoderm elongates through compression-extension

Thomson, L.; Muresan, L.; Steventon, B.

10.1101/2021.03.11.434927 — developmental biology — Posted on 2021-03-11

3259 Loss of SETD1B results in the redistribution of genomic H3K4me3 in the oocyte

Hanna, C. W.; Huang, J.; Belton, C.; Reinhardt, S.; Dahl, A.; Andrews, S.; Stewart, A. F.; Kranz, A.; Kelsey, G.

10.1101/2021.03.11.434836 — developmental biology — Posted on 2021-03-11

3260 The feedback regulator Nord controls Dpp/BMP signaling via extracellular interaction with Dally in the Drosophila wing

Gibson, M. C.; Akiyama, T.; Seidel, C. W.

10.1101/2021.03.11.434947 — developmental biology — Posted on 2021-03-11

3261 Low intensity repetitive transcranial magnetic stimulation drives structural synaptic plasticity in the young and aged motor cortex.

Tang, A.; Bennett, W.; Bindoff, A.; Collins, J.; Garry, M.; Summers, J.; Hinder, M.; Rodger, J.; Canty, A.

10.1101/2021.03.10.434706 — neuroscience — Posted on 2021-03-11

3262 Neural Basis of the Delayed Gratification

Gao, Z.; Wang, H.; Lu, C.; Froudist-Walsh, S.; Chen, M.; Wang, X.-J.; Hu, J.; Sun, W.

10.1101/2021.03.10.434739 — neuroscience — Posted on 2021-03-11

3263 Diversify your workflow! - An inconvenient suggestion to analyze spike data from intracranial recordings

Okkesim, S.; Rastogi, S.; Christ, O.; Hubka, P.; Rosskothen-Kuhl, N.; Hofmann, U.

10.1101/2021.03.10.434718 — neuroscience — Posted on 2021-03-11

3264 Distinct generation of subjective vividness and confidence during naturalistic memory retrieval in angular gyrus

Zou, F.; Kwok, S. C.

10.1101/2021.03.10.434526 — neuroscience — Posted on 2021-03-11

3265 Excitatory postsynaptic calcium transients at Aplysia sensory-motor neuron synapses allow for quantal examination of synaptic strength over multiple days in culture

Dunn, T. W.; Sossin, W. S.

10.1101/2021.03.10.434766 — neuroscience — Posted on 2021-03-11

3266 Predicting the fitness costs of complex mutations

Yubero, P.; Poyatos, J. F.

10.1101/2021.03.10.434744 — systems biology — Posted on 2021-03-11

3267 The rise and fall of the photoinhibition-related energy dissipation qI

Nawrocki, W. J.; Liu, X.; Raber, B.; Hu, C.; de Vitry, C.; Bennett, D. I. G.; Croce, R.

10.1101/2021.03.10.434601 — plant biology — Posted on 2021-03-11

3268 New opabiniid diversifies the weirdest wonders of the euarthropod lower stem group

Pates, S.; Wolfe, J. M.; Lerosey-Aubril, R.; Daley, A. C.; Ortega-Hernández, J.

10.1101/2021.03.10.434726 — paleontology — Posted on 2021-03-11

3269 A Comparative Analysis of Novel Deep Learning Models and Ensemble Learning Models to Predict the Allergenicity of Food Allergens

Wang, L.; Niu, D.; Zhao, X.; Wang, X.; Hao, M.; Che, H.

10.1101/2021.03.10.434710 — bioinformatics — Posted on 2021-03-11

3270 Low-Cost, Modular Modification to a Desktop 3D Printer for General Purpose Gel/Paste Extrusion & Direct Ink Writing

Leech, D. J.; Lightfoot, S.; Huson, D.; Stratakos, A. C.

10.1101/2021.03.10.434735 — bioengineering — Posted on 2021-03-11

3271 Corticosterone differentially modulates time-dependent fear generalization following mild or moderate fear conditioning training in rats

dos Santos Correa, M.; Vaz, B. d. S.; Menezes, B. S.; Ferreira, T. L.; Tiba, P. A.; Fornari, R. V.

10.1101/2021.03.10.434749 — animal behavior and cognition — Posted on 2021-03-11

3272 Whole-genome analysis of multiple wood ant population pairs supports similar speciation histories, but different degrees of gene flow, across their European range

Portinha, B.; Avril, A.; Bernasconi, C.; Helanterä, H.; Monaghan, J.; Seifert, B.; Sousa, V. C.; Kulmuni, J.; Nouhaud, P.

10.1101/2021.03.10.434741 — evolutionary biology — Posted on 2021-03-11

3273 Cooperative herbivory between two important pests of rice

Liu, Q.; Hu, X.; Su, S.; Peng, Y.; Ye, G.; Lou, Y.; Turlings, T. C. J.; Li, Y.

10.1101/2021.03.10.434708 — ecology — Posted on 2021-03-11

3274 Phylogeography, codon usage, and DNA barcoding of lesser short nosed fruit bat (Cynopterus brachyotis Muller, 1838) populations in Indonesia

Wibowo, A. A.

10.1101/2021.03.10.434719 — ecology — Posted on 2021-03-11

3275 Age and Sex Effects on Advanced White Matter Microstructure Measures in 15,628 UKBiobank Participants

Lawrence, K. E.; Nabulsi, L.; Santhalingam, V.; Abaryan, Z.; Villalon-Reina, J. E.; Nir, T. M.; Ba Gari, I.; Zhu, A. H.; Haddad, E.; Muir, A. M.; Laltoo, E.; Jahanshad, N.; Thompson, P. M.

10.1101/2020.09.18.304345 — neuroscience — Posted on 2021-03-11

3276 Multi-Omic Profiling of the Liver Across Diets and Age in a Diverse Mouse Population

Williams, E. G.; Pfister, N.; Roy, S.; Statzer, C.; Haverty, J.; Ingels, J.; Bohl, C.; Hasan, M.; Cuklina, J.; Buhlmann, P.; Zamboni, N.; Lu, L.; Ewald, C. Y.; Williams, R. W.; Aebersold, R.

10.1101/2020.08.20.222968 — systems biology — Posted on 2021-03-11

3277 Capturing scientific knowledge in computable form

Wong, J. V.; Franz, M.; Siper, M. C.; Fong, D.; Durupinar, F.; Dallago, C.; Luna, A.; Giorgi, J. M.; Rodchenkov, I.; Babur, O.; Gyori, B. M.; Bachman, J. A.; Demir, E.; Bader, G. D.; Sander, C.

10.1101/2021.03.10.382333 — bioinformatics — Posted on 2021-03-11

3278 Identification of downstream effectors of retinoic acid specifying the zebrafish pancreas by integrative genomics.

Lopez-Perez, A. R.; Balwierz, P. J.; Lenhard, B.; Muller, F.; Manfroid, I.; Voz, M.; Peers, B.; Wardle, F. C.

10.1101/2020.11.09.341016 — genomics — Posted on 2021-03-11

3279 Environmental stressors induced strong small-scale phenotypic differentiation in a wide-dispersing marine snail

Bonel, N.; Pointier, J.-P.; Alda, P.

10.1101/2020.10.06.327767 — ecology — Posted on 2021-03-11

3280 Regional gene expression patterns are associated with task-specific brain activationduring reward and emotion processing measured with functional MRI

Komorowski, A.; Vidal, R.; Singh, A.; Murgas, M.; Pena-Centeno, T.; Gryglewski, G.; Kasper, S.; Wiltfang, J.; Lanzenberger, R.; Goya-Maldonado, R.

10.1101/2020.06.27.175257 — neuroscience — Posted on 2021-03-11

3281 Unsupervised Learning Predicts Human Perception and Misperception of Gloss

Storrs, K. R.; Anderson, B. L.; Fleming, R. W.

10.1101/2020.04.07.026120 — neuroscience — Posted on 2021-03-11

3282 Structure-function Specialisation of the Interfascicular Matrix in the Human Achilles Tendon

Patel, D.; Zamboulis, D. E.; Spiesz, E. M.; Birch, H. L.; Clegg, P. D.; Thorpe, C. T.; Screen, H. R. C.

10.1101/2021.02.22.432199 — bioengineering — Posted on 2021-03-11

3283 Roles of adenine methylation and genetic mutations in adaptation to different temperatures in Serratia marcescens

Bruneaux, M.; Kronholm, I.; Ashrafi, R.; Ketola, T.

10.1101/822080 — evolutionary biology — Posted on 2021-03-11

3284 The cAMP effector PKA mediates Moody GPCR signaling in Drosophila blood-brain barrier formation and maturation

Li, X.; Fetter, R.; Schwabe, T.; Jung, C.; Steller, H.; Gaul, U.

10.1101/2021.03.10.434865 — developmental biology — Posted on 2021-03-11

3285 A wing growth organizer in a hemimetabolous insect suggests wing origin

Ohde, T.; Mito, T.; Niimi, T.

10.1101/2021.03.10.434860 — developmental biology — Posted on 2021-03-11

3286 Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics

Zhang, A. M.; de Winter, T. J. J.; Wang, S.; Flibotte, S.; Zhao, Y. B.; Hu, X.; Li, H.; Schaeffer, D. F.; Johnson, J. D.; Kopp, J. L.

10.1101/2021.03.10.434504 — cancer biology — Posted on 2021-03-11

3287 Oxidative stress induced by tBHP in human normal colon cells by label free Raman spectroscopy and imaging.The protective role of natural antioxidants in the form of β-carotene

Pluska, B. B.; Beton, K.

10.1101/2021.02.16.431391 — cancer biology — Posted on 2021-03-11

3288 Optimising expression quantitative trait locus mapping workflows for single-cell studies

Cuomo, A. S.; Alvari, G.; Azodi, C. B.; single-cell eQTLGen consortium, ; McCarthy, D. J.; Bonder, M. J.

10.1101/2021.01.20.427401 — genetics — Posted on 2021-03-11

3289 EEG Cross-Frequency Phase Synchronization as an Index of Memory Matching in Visual Search

Biel, A. L.; Minarik, T.; Sauseng, P.

10.1101/2020.09.22.306431 — neuroscience — Posted on 2021-03-11

3290 pDeep3: Towards More Accurate Spectrum Prediction with Fast Few-Shot Learning

Tarn, C.; Zeng, W.-F.

10.1101/2020.09.13.295105 — bioinformatics — Posted on 2021-03-11

3291 Computationally Grafting an IgE Epitope onto a Scaffold: Implications for a Pan Anti-Allergy Vaccine Design

Sabban, S. S.

10.1101/2020.09.14.296392 — bioinformatics — Posted on 2021-03-11

3292 Chasing the cardiomyopathy modifier genes: Integrative computational analysis interweave the missing links in cardiomyopathy diseasome

Chauhan, P. K.; Sowdhamini, R.

10.1101/2021.02.26.433014 — bioinformatics — Posted on 2021-03-11

3293 Navigating the amino acid sequence space between functional proteins using a deep learning framework

Bitard-Feildel, T.

10.1101/2020.11.09.375311 — bioinformatics — Posted on 2021-03-11

3294 RNA-silencing induces target gene relocalization toward a specialized nuage domain

Mello, C.; Yang, Y.; Grunwald, D.; Priess, J.

10.1101/2021.03.09.434681 — genetics — Posted on 2021-03-11

3295 Growth differentiation factor 15 increases in both cerebrospinal fluid and serum during pregnancy

Andersson-Hall, U.; Svedin, P.; Mallard, C.; Blennow, K.; Zetterberg, H.; Holmäng, A.

10.1101/2021.03.10.434730 — physiology — Posted on 2021-03-10

3296 Activation of innate immunity by neutral polysaccharides from broccoli buds

Miyashita, A.; Kataoka, K.; Sekimizu, K.

10.1101/2021.03.10.434731 — biochemistry — Posted on 2021-03-10

3297 The CATP-8/P5A-type ATPase functions in multiple pathways during neuronal patterning

Tang, L.; Trivedi, M.; Freund, J.; Salazar, C.; Ramirez-Suarez, N.; Lee, G.; Rahman, M.; Wang, Y.; Grant, B.; Bülow, H. E.

10.1101/2021.03.10.434729 — developmental biology — Posted on 2021-03-10

3298 Visualizing subcellular structures in neuronal tissue with expansion microscopy

Campbell, L. A.; Pannoni, K. E.; Savory, N. A.; Lal, D.; Farris, S.

10.1101/2020.12.05.408724 — neuroscience — Posted on 2021-03-10

3299 Odor-evoked Increases in Spiking Variability in the Olfactory Bulb

Ly, C.; Barreiro, A. K.; Gautam, S. H.; Shew, W. L.

10.1101/2021.03.05.434131 — neuroscience — Posted on 2021-03-10

3300 The NOTCH3 Downstream Target HEYL Regulates Human Airway Epithelial Club Cell Differentiation

Bodas, M.; Subramaniyan, B.; Moore, A. R.; Metcalf, J. P.; Ocanas, S. R.; Freeman, W. M.; Georgescu, C.; Wren, J. D.; Walters, M. S.

10.1101/2021.03.10.434858 — cell biology — Posted on 2021-03-10

3301 TCR signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 NPC subcomplex via phosphorylation of RanGAP1 by PKC-θ

Li, Y.; He, Y.; Yang, Z.; Zhao, C.-s.; Gong, Y.; Xiao, Z.; Li, Y.-y.; Chen, Y.; Feng, D.; Altman, A.

10.1101/2021.03.10.434793 — cell biology — Posted on 2021-03-10

3302 CASPAM: a triple modality biosensor for multiplexed imaging of caspase network activity

Habif, M.; Corbat, A. A.; Silberberg, M.; Grecco, H. E.

10.1101/2021.03.10.434623 — cell biology — Posted on 2021-03-10

3303 Identification of molecular candidates which regulate calcium-dependent CD8+ T-cell cytotoxicity

Zöphel, S.; Schwär, G.; Nazarieh, M.; Konetzki, V.; Hoxha, C.; Meese, E.; Hoth, M.; Helms, V.; Hamed, M.; Schwarz, E. C.

10.1101/2020.12.22.423945 — immunology — Posted on 2021-03-10

3304 Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike

Tong, P.; Gautam, A.; Windsor, I.; Travers, M.; Chen, Y.; Garcia, N.; Whiteman, N.; McKay, L.; Lelis, F. J. N.; Habibi, S.; Cai, Y.; Rennick, L. J.; Duprex, W. P.; McCarthy, K.; Lavine, C. L.; Zuo, T.; Lin, J.; Zuiani, A.; Feldman, J.; MacDonald, E. A.; Hauser, B. M.; Griffths, A.; Seaman, M. S.; Schmidt, A. G.; Chen, B.; Neuberg, D.; Bajic, G.; Harrison, S. C.; Wesemann, D. R.

10.1101/2021.03.10.434840 — immunology — Posted on 2021-03-10

3305 Phosphorylation triggers presynaptic phase separation of Liprin-α3 to control active zone structure

Emperador Melero, J.; Wong, M. Y.; Wang, S. S. H.; De Nola, G.; Kirchhausen, T.; Kaeser, P. S.

10.1101/2020.10.28.357574 — neuroscience — Posted on 2021-03-10

3306 Meningeal dendritic cells-astrocytes interactions elevate the kynurenine metabolic pathway to sustain neuropathic pain

Maganin, A. G.; Souza, G. R.; Fonseca, M. D.; Lopes, A. H.; Guimaraes, R. M.; Dagostin, A.; Cecilio, N. T.; Mendes, A. S.; Gomes, F. I.; Marques, L. M.; Silva, R. L.; Arruda, L. M.; Santana, D. A.; Lemos, H.; Huang, L.; Davoli-Ferreira, M.; Coelho, D. S.; Santanna, M. B.; Kusuda, R. K.; Talbot, J.; Pacholczyk, G.; Buqui, G. A.; Lopes, N. P.; Alves-Filho, J. C.; Leao, R.; OConnor, J. C.; Cunha, F. Q.; Mellor, A.; Cunha, T. M.

10.1101/2021.01.25.428142 — neuroscience — Posted on 2021-03-10

3307 Hypothalamic perineuronal nets are regulated by sex and dietary interventions

Zhang, N.; Yan, Z.; Liu, H.; Yu, M.; He, Y.; Liu, H.; Liang, C.; Tu, L.; Wang, L.; Yin, N.; Han, J.; Scarcelli, N.; Yang, Y.; Wang, C.; Zeng, T.; Chen, L.; Xu, Y.

10.1101/2021.03.07.434286 — neuroscience — Posted on 2021-03-10

3308 Dense time-course gene expression profiling of the Drosophila melanogaster innate immune response

Schlamp, F.; Delbare, S. Y. N.; Early, A. M.; Wells, M. T.; Basu, S.; Clark, A. G.

10.1101/2020.06.25.172452 — systems biology — Posted on 2021-03-10

3309 Transfer learning framework for cell segmentation with incorporation of geometric features

Jin, Y.; Toberoff, A.; Azizi, E.

10.1101/2021.02.28.433289 — systems biology — Posted on 2021-03-10

3310 Examining the quality and fertilization competence of bovine ejaculate with low progressive motility, should we give it a chance?

Li, Y.; Kalo, D.; Elbaz, A. K.; Zeron, Y.; Roth, Z.

10.1101/2021.02.24.432701 — physiology — Posted on 2021-03-10

3311 Multiple introductions of multidrug-resistant typhoid associated with acute infection and asymptomatic carriage, Kenya

Kariuki, S.; Dyson, Z. A.; Mbae, C.; Ngetich, R.; Kavai, S.; Wairimu, C.; Anyona, S.; Gitau, N.; Onsare, R. S.; Ongandi, B.; Duchene, S.; Ali, M.; Clemens, J. D.; Holt, K. E.; Dougan, G.

10.1101/2021.03.10.434750 — physiology — Posted on 2021-03-10

3312 Differential expression of H2A isoforms contribute to tissue and lineage specificity with HIST2H2AC as a potential cancer biomarker

Shah, S. G.; Rashid, M.; Natu, A.; Gupta, S.

10.1101/2021.03.10.434738 — cancer biology — Posted on 2021-03-10

3313 Integrated Systems-Analysis of the Human and Murine Pancreatic Cancer Glycomes Reveal a Tumor Promoting Role for ST6GAL1

Kurz, E.; Chen, S.; Vucic, E.; Baptiste, G.; Loomis, C.; Agarwal, P.; Hadju, C.; Bar-Sagi, D.; Mahal, L. K.

10.1101/2021.03.10.434864 — cancer biology — Posted on 2021-03-10

3314 A Focused Small-Molecule Screen Identifies PHA-680626 as an Amphosteric Inhibitor Disrupting the Interaction between Aurora-A and N-Myc

Souvalidou, F.; Boi, D.; Montanari, R.; Polverino, F.; Marini, G.; Capelli, D.; Pochetti, G.; Contestabile, R.; Trisciuoglio, D.; Tramonti, A.; Carpinelli, P.; Ascanelli, C.; Lindon, C.; De Leo, A.; Di Santo, R.; Costi, R.; Guarguaglini, G.; Paiardini, A.

10.1101/2021.03.10.433854 — cancer biology — Posted on 2021-03-10

3315 A photoswitchable helical peptide with light-controllable interface / transmembrane topology in lipidic membranes

Gutierrez-Salazar, M.; Santamaria-Aranda, E.; Schaar, L.; Salgado, J.; Sampedro, D.; Lorenz-Fonfria, V. A.

10.1101/2021.03.10.434736 — biophysics — Posted on 2021-03-10

3316 Tight junction ZO proteins maintain tissue fluidity, ensuring efficient collective cell migration

Skamrahl, M.; Pang, H.; Ferle, M.; Gottwald, J.; Ruebeling, A.; Maraspini, R.; Honigmann, A.; Oswald, T. A.; Janshoff, A.

10.1101/2021.03.10.434539 — biophysics — Posted on 2021-03-10

3317 In situ photopatterning of cell laden biomaterials for spatially organized 3D cell cultures in a microfluidic chip

Ortiz-Cardenas, J. E.; Zatorski, J. M.; Arneja, A.; Montalbine, A. N.; Munson, J. M.; Luckey, C. J.; Pompano, R. R.

10.1101/2020.09.09.287870 — bioengineering — Posted on 2021-03-10

3318 The bacterial amyloids phenol soluble modulins from Staphylococcus aureus catalyze alpha-synuclein aggregation

Haikal, C.; Ortigosa, L.; Bernfur, K.; Svanbergsson, A.; Linse, S.; Li, J.-Y.

10.1101/2021.03.10.434765 — biochemistry — Posted on 2021-03-10

3319 Butyryl/Caproyl-CoA:Acetate CoA-Transferase: Cloning, Expression and Characterization of the Key Enzyme Involved in Medium-Chain Fatty Acid Biosynthesis

Yang, Q.; Guo, S.; Lu, Q.; Tao, Y.; Zheng, D.; Zhou, Q.; Liu, J.

10.1101/2021.03.10.434813 — biochemistry — Posted on 2021-03-10

3320 Coding Recognition of the Dose-Effect Interdependence of Small Biomolecules Encrypted on Paired Chromatographic-Based Microassay Arrays

Deng, Y.; Lin, Z.; Cheng, Y.

10.1101/2021.03.10.434720 — biochemistry — Posted on 2021-03-10

3321 Automated CUT&Tag profiling of chromatin heterogeneity in mixed-lineage leukemia

Janssens, D.; Meers, M. P.; Wu, S. J.; Babaeva, E.; Meshinchi, S.; Sarthy, J. F.; Ahmad, K.; Henikoff, S.

10.1101/2020.10.06.328948 — genomics — Posted on 2021-03-10

3322 Inter-tissue convergence of gene expression and loss of cellular identity during ageing

Izgi, H.; Han, D.; Isildak, U.; Huang, S.; Kocabiyik, E.; Khaitovich, P.; Somel, M.; Dönertas, H. M.

10.1101/2021.03.02.432281 — genomics — Posted on 2021-03-10

3323 Contrasting Effects of Western vs. Mediterranean Diets on Monocyte Inflammatory Gene Expression and Social Behavior in a Primate Model

Johnson, C. S. C.; Shively, C. A.; Michalson, K. T.; Lea, A. J.; DeBo, R. J.; Howard, T. D.; Hawkins, G. A.; Appt, S. E.; Liu, Y.; McCall, C. E.; Herrington, D.; Ip, E. H.; Register, T. C.; Snyder-Mackler, N.

10.1101/2020.01.27.917567 — genomics — Posted on 2021-03-10

3324 The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite

Zhang, M.; Wang, C.; Oberstaller, J.; Thomas, P.; Otto, T. D.; Boyapalle, S.; Adapa, S. R.; Button-Simons, K.; Mayho, M.; Rayner, J. C.; Ferdig, M. T.; Jiang, R. H. Y.; Adams, J. H.

10.1101/2020.12.10.419788 — genomics — Posted on 2021-03-10

3325 FDR control in GWAS with population structure

Sesia, M.; Bates, S.; Candes, E.; Marchini, J.; Sabatti, C.

10.1101/2020.08.04.236703 — genomics — Posted on 2021-03-10

3326 Mitochondrial genome sequencing of marine leukemias reveals cancer contagion between clam species in the Seas of Southern Europe

Garcia-Souto, D.; Bruzos, A. L.; Diaz-Costas, S.; Rocha, S.; Pequeno, A.; Roman-Lewis, C. F.; Alonso, J.; Rodriguez, R.; Costas, D.; Rodriguez-Castro, J.; Villanueva, A.; Silva, L.; Valencia, J. M.; Annona, G.; Tarallo, A.; Ricardo, F.; Bratos Cetinic, A.; Posada, D.; Pasantes, J. J.; TUBIO, J. M.

10.1101/2021.03.10.434714 — genomics — Posted on 2021-03-10

3327 Evolutionary coupling range varies widely among enzymes depending on selection pressure

Echave, J.

10.1101/2020.12.19.423588 — evolutionary biology — Posted on 2021-03-10

3328 Developmental innovations promote species diversification in mushroom-forming fungi

Varga, T.; Földi, C.; Bense, V.; Nagy, L. G.

10.1101/2021.03.10.434564 — evolutionary biology — Posted on 2021-03-10

3329 Ecosystem size and complexity dictate riverine biodiversity

Terui, A.; Kim, S.; Dolph, C. L.; Kadoya, T.; Miyazaki, Y.

10.1101/2021.03.08.434467 — ecology — Posted on 2021-03-10

3330 Drivers of Rift Valley fever virus persistence and the impact of control measures in a spatially heterogeneous landscape: the case of the Comoros archipelago, 2004-2015

Tennant, W. S. D.; Cardinale, E.; Cetre-Sossah, C.; Moutroifi, Y.; Le Godais, G.; Colombi, D.; Spencer, S. E. F.; Tildesley, M. J.; Keeling, M. J.; Charafouddine, O.; Colizza, V.; Edmunds, W. J.; Metras, R.

10.1101/2021.03.10.434721 — ecology — Posted on 2021-03-10

3331 Factors Shaping Young and Mature Bacterial Biofilm Communities in Two Drinking Water Distribution Networks

Cheng, D.; Leifels, M.; Miccolis, C.; Wuertz, S.; Thompson, J. R.; Szewzyk, U.; Whittle, A. J.

10.1101/2021.03.10.434709 — ecology — Posted on 2021-03-10

3332 Cell-specific alterations in Pitx1 regulatory landscape activation caused by the loss of a single enhancer

Rouco, R.; Bompadre, O.; Rauseo, A.; Fazio, O.; Thorel, F.; Peraldi, R.; Andrey, G.

10.1101/2021.03.10.434611 — developmental biology — Posted on 2021-03-10

3333 Lamb1a regulates atrial growth by limiting excessive, contractility-dependent second heart field addition during zebrafish heart development

Derrick, C. J.; Pollitt, E. J. G.; Sanchez Sevilla Uruchurtu, A.; Hussein, F.; Noel, E. S.

10.1101/2021.03.10.434727 — developmental biology — Posted on 2021-03-10

3334 Cell-type-specific chromatin occupancy by the pioneer factor Zelda drives key developmental transitions in Drosophila

Larson, E. D.; Komori, H.; Gibson, T. J.; Ostgaard, C. M.; Hamm, D. C.; Schnell, J. M.; Lee, C.-Y.; Harrison, M. M.

10.1101/2021.03.10.434844 — developmental biology — Posted on 2021-03-10

3335 SNHG16 promotes cell proliferation and inhibits cell apoptosis via regulation of the miR-1303p/STARD9 axis in renal cell carcinoma

Cheng, T.; Shuang, W.; Ye, D.; Zhang, W.; Yang, Z.; Fang, W.; Xu, H.; Gu, M.; Xu, W.; Guan, C.

10.1101/2021.03.10.434814 — cell biology — Posted on 2021-03-10

3336 ExoBow: A transgenic strategy to study CD63 exosomes in vivo

Adem, B.; Bastos, N.; Ruivo, C. F.; Vieira, P. F.; Seidler, B.; Machado, J. C.; Saur, D.; Cai, D.; Melo, S. A.

10.1101/2021.03.10.434407 — cell biology — Posted on 2021-03-10

3337 Courtship ritual of male and female nuclei during fertilisation in Neurospora crassa

Brun, S.; Kuo, H.-C.; Jeffree, C. E.; Thomson, D. D.; Read, N.

10.1101/2021.03.10.434724 — cell biology — Posted on 2021-03-10

3338 Myogenetic oligodeoxynucleotide (myoDN) recovers the differentiation of skeletal muscle myoblasts deteriorated by diabetes mellitus

Nakamura, S.; Yonekura, S.; Shimosato, T.; Takaya, T.

10.1101/2021.03.10.434717 — cell biology — Posted on 2021-03-10

3339 Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response

Nguyen, L. C.; Yang, D.; Nicolaescu, V.; Best, T.; Chen, S.; Friesen, J. B.; Drayman, N.; Mohamed, A.; Dann, C.; Silva, D.; Gula, H.; Jones, K. A.; Millis, J. M.; Dickinson, B. C.; Tay, S.; Oakes, S. A.; Pauli, G. F.; Meltzer, D. O.; Randall, G.; Rosner, M. R.

10.1101/2021.03.10.432967 — microbiology — Posted on 2021-03-10

3340 Metapopulation Structure of Diatom-associated Marine Bacteria

Qu, L.; Feng, X.; Chen, Y.; Li, L.; Wang, X.; Hu, Z.; Wang, H.; Luo, H.

10.1101/2021.03.10.434754 — microbiology — Posted on 2021-03-10

3341 A genome-annotated bacterial collection of the barley rhizosphere microbiota

Robertson-Albertyn, S.; Concas, F.; Brown, L. H.; Orr, J. N.; Abbott, J. C.; George, T. S.; Bulgarelli, D.

10.1101/2021.03.10.434690 — microbiology — Posted on 2021-03-10

3342 Assessing the effectiveness of oxathiapiprolin towards Phytophthora agathidicida, the causal agent of kauri dieback disease

Lacey, R. F.; Fairhurst, M. J.; Daley, K. J.; Ngata-Aerengamate, T. A.; Patterson, H. R.; Patrick, W. M.; Gerth, M. L.

10.1101/2021.03.10.434845 — microbiology — Posted on 2021-03-10

3343 Droplet-based single cell RNA sequencing of bacteria identifies known and previously unseen cellular states

McNulty, R. A.; Sritharan, D.; Liu, S.; Hormoz, S.; Rosenthal, A. Z.

10.1101/2021.03.10.434868 — microbiology — Posted on 2021-03-10

3344 Ecophysiology of the cosmopolitan OM252 bacterioplankton (Gammaproteobacteria)

Savoie, E. R.; Lanclos, V. C.; Henson, M. W.; Cheng, C.; Getz, E. W.; Barnes, S. J.; LaRowe, D. E.; Rappe, M. S.; Thrash, J. C.

10.1101/2021.03.09.434695 — microbiology — Posted on 2021-03-10

3345 Influenza-induced activation of recruited alveolar macrophages during the early inflammatory phase drives lung injury and lethality

Koch, C. M.; Anekalla, K.; Hu, Y.-S.; Davis, J. M.; Ciesielski, M.; Gadhvi, G.; Chen, S.-Y.; Turner, M.; Cheng, Y.; Coates, B. M.; Abdala-Valencia, H.; Reyfman, P. A.; Misharin, A. V.; Budinger, G. S.; Winter, D. R.; Ridge, K. M.

10.1101/2020.06.08.141309 — immunology — Posted on 2021-03-10

3346 The dual function monoclonal antibodies VIR-7831 and VIR-7832 demonstrate potent in vitro and in vivo activity against SARS-CoV-2

Cathcart, A. L.; Havenar-Daughton, C.; Lempp, F. A.; Ma, D.; Schmid, M.; Agostini, M. L.; Guarino, B.; Di iulio, J.; Rosen, L.; Tucker, H.; Dillen, J.; Subramanian, S.; Sloan, B.; Bianchi, S.; Wojcechowskyj, J.; Zhou, J.; Kaiser, H.; Chase, A.; Montiel-Ruiz, M.; Czudnochowski, N.; Cameroni, E.; Ledoux, S.; Colas, C.; Soriaga, L.; Telenti, A.; Hwang, S.; Snell, G.; Virgin, H. W.; Corti, D.; Hebner, C. M.

10.1101/2021.03.09.434607 — immunology — Posted on 2021-03-10

3347 Bruton's Tyrosine Kinase Supports Gut Mucosal Immunity and Commensal Microbiome Recognition in Autoimmune Arthritis

Bonami, R. H.; Thurman, C. E.; Nyhoff, L. E.; Westlake, C. S.; Barron, B. B.; Kendall, P. L.

10.1101/2021.03.10.434762 — immunology — Posted on 2021-03-10

3348 Development of Equine Immunoglobulin Fragment F(ab')2 with High Neutralizing Capability against SARS-CoV-2

Gupta, D.; Ahmed, F.; Tandel, D.; Parthasarathy, H.; Vedagiri, D.; Sah, V.; Bodduluru, K. M.; Daga, S. S.; Khan, R. A.; Kondiparthi, C.; Savari, P.; Jain, S. H.; Daga, J. S.; Reddy, S.; Khan, N.; Harshan, K. H.

10.1101/2021.03.09.434030 — immunology — Posted on 2021-03-10

3349 Gait-phase modulates alpha and beta oscillations in the pedunculopontine nucleus

He, S.; Deli, A.; Fischer, P.; Wiest, C.; Huang, Y.; Martin, S.; Khawaldeh, S.; Aziz, T. Z.; Green, A. L.; Brown, P.; Tan, H.

10.1101/2021.03.05.434086 — neuroscience — Posted on 2021-03-10

3350 Assessing methods for geometric distortion compensation in 7T gradient echo fMRI data

Schallmo, M.-P.; Weldon, K. B.; Burton, P. C.; Sponheim, S. R.; Olman, C. A.

10.1101/2020.07.02.184515 — neuroscience — Posted on 2021-03-10

3351 Acoustic context modulates natural sound discrimination in auditory cortex through frequency specific adaptation

Lopez Jury, L.; Garcia-Rosales, F.; Gonzalez-Palomares, E.; Koessl, M.; Hechavarria, J. C.

10.1101/2021.02.08.430293 — neuroscience — Posted on 2021-03-10

3352 Shank3 influences mammalian sleep development

Schoch, H.; Medina, E.; Wintler, T. P.; Ford, K. E.; Singletary, K. G.; Peixoto, L.

10.1101/2021.03.10.434728 — neuroscience — Posted on 2021-03-10

3353 Seasonal and long-term consequences of esca on grapevine stem xylem integrity

Bortolami, G.; Farolfi, E.; Badel, E.; Burlett, R.; Cochard, H.; Ferrer, N.; King, A.; Lamarque, L. J.; Lecomte, P.; Marchesseau Marchal, M.; Pouzoulet, J.; Torres-Ruiz, J. M.; Trueba, S.; Delzon, S.; Gambetta, G. A.; Delmas, C. E. L.

10.1101/2020.09.07.282582 — plant biology — Posted on 2021-03-10

3354 CRISPR enriches for cells with mutations in a p53-related interactome, and this can be inhibited.

Jiang, L.; Ingelshed, K.; Shen, Y.; Boddul, S. V.; Iyer, V. S.; Kasza, Z.; Sedimbi, S.; Lane, D. P.; Wermeling, F.

10.1101/2021.03.10.434760 — cancer biology — Posted on 2021-03-10

3355 A redox-dependent mechanism for AMPK dysregulation interrupts metabolic adaptation of cancer under glucose deprivation

Lee, Y.; Itahana, Y.; Ong, C. C.; Itahana, K.

10.1101/2021.03.10.434352 — cancer biology — Posted on 2021-03-10

3356 Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiology

Ng, C. A.; Farr, J.; Young, P.; Windley, M. J.; Perry, M. D.; Hill, A. P.; Vandenberg, J. I.

10.1101/2021.02.02.427891 — biophysics — Posted on 2021-03-10

3357 Post-transcriptional regulation of glutamate metabolism of Pichia pastoris and development of a glutamate-inducible yeast expression system

Dey, T.; Rangarajan, P.

10.1101/2021.03.10.434748 — biochemistry — Posted on 2021-03-10

3358 Variable autoinhibition among deafness-associated variants of Diaphanous 1 (DIAPH1)

Lakha, R.; Montero, A. M.; Jabeen, T.; Costeas, C. C.; Ma, J.; Vizcarra, C. L.

10.1101/2021.03.10.434847 — biochemistry — Posted on 2021-03-10

3359 Effect of Voluntary Adolescent Alcohol Consumption on Encoding of Decision-Related Variables in Prefrontal Cortex

Roitman, J. D.; Corwin, S.

10.1101/2021.03.09.434599 — neuroscience — Posted on 2021-03-10

3360 Relative salience signaling within a thalamo-orbitofrontal circuit governs learning rate

Namboodiri, V.; Hobbs, T.; Trujillo-Pisanty, I.; Simon, R.; Gray, M.; Stuber, G.

10.1101/2020.04.28.066878 — neuroscience — Posted on 2021-03-10

3361 Polypide anatomy of hornerid bryozoans (Stenolaemata: Cyclostomatida)

Tamberg, Y.; Batson, P. B.; Napper, R.

10.1101/2021.03.09.433978 — zoology — Posted on 2021-03-10

3362 DeepSea: An efficient deep learning model for automated cell segmentation and tracking

Zargari, A.; Lodewijk, G. A.; Neudorf, C. W.; Araghbidikashani, K.; Mashhadi, N.; Rubio, S.; Hinck, L.; Shariati, S. A.

10.1101/2021.03.10.434806 — systems biology — Posted on 2021-03-10

3363 Discovery of Dynamical Network Models for Genetic Circuits from Time-Series Data with Incomplete Measurements

Yeung, E.; Kim, J.; Yuan, Y.; Goncalves, J.; Murray, R. M.

10.1101/2021.03.10.434835 — synthetic biology — Posted on 2021-03-10

3364 A New Protocol for Targeted insertion using CRISPR-Cas9, Oligo Single-Stranded DNA and Protoplast Regeneration

Hsu, C.-T.; Yuan, Y.-H.; Lin, Y.-C.; Lin, S.; Cheng, Q.-W.; Wu, F.-H.; Sheen, J.; Shih, M.-C.; Lin, C.-S.

10.1101/2021.03.09.434087 — plant biology — Posted on 2021-03-10

3365 Standing genetic variation of the AvrPm17 avirulence gene in powdery mildew limits the effectiveness of an introgressed rye resistance gene in wheat

Mueller, M. C.; Kunz, L.; Schudel, S.; Kammerecker, S.; Isaksson, J.; Wyler, M.; Graf, J.; Sotiropoulos, A. G.; Praz, C. R.; Wicker, T.; Bourras, S.; Keller, B.

10.1101/2021.03.09.433749 — plant biology — Posted on 2021-03-10

3366 Identification and characterization of two transmembrane proteins required for virulence of Ustilago maydis

Weiland, P.; Altegoer, F.

10.1101/2021.03.09.434588 — plant biology — Posted on 2021-03-10

3367 Direct sulphate-TOR signalling controls transcriptional reprogramming for shoot apex activation in Arabidopsis

Yu, Y.; Zhong, Z.; Xiang, C.; Xu, P.; Xiong, Y.

10.1101/2021.03.09.434511 — plant biology — Posted on 2021-03-10

3368 SSR1 is a vital regulator in plant mitochondrial iron-sulfur biosynthesis

Feng, X.; Han, H.; Bonea, D.; Liu, J.; Ying, W.; Cai, Y.; Zhang, M.; Lu, Y.; Zhao, R.; Hua, X.

10.1101/2021.03.09.434627 — plant biology — Posted on 2021-03-10

3369 The Intervening Domain Is Required For DNA-binding and Functional Identity of Plant MADS Transcription Factors

Lai, X.; Vega-Leon, R.; Hugouvieux, V.; Blanc-Mathieu, R.; van der Wal, F.; Lucas, J.; Silva, C. S.; Jourdain, A.; Muino, J.; Nanao, M. H.; Immink, R.; Kaufmann, K.; Parcy, F.; Smaczniak, C.; Zubieta, C.

10.1101/2021.03.10.434815 — plant biology — Posted on 2021-03-10

3370 DEVELOPMENT OF A SOYBEAN MATURITY PREDICTION MODEL FOR SOYBEAN GROWN IN AFRICAN ENVIRONMENTS

Marcillo, G.; Martin, N.; Diers, B.; Da Fonseca, M. S.; Leles, E.

10.1101/2021.03.09.434647 — plant biology — Posted on 2021-03-10

3371 An objective-based prioritization approach to improve trophic complexity through ecological restoration

Ladouceur, E.; McGowan, J.; Huber, P.; Possingham, H.; Scridel, D.; van Klink, R.; Poschlod, P.; Cornelissen, J. H. C.; Bonomi, C.; Jimenez-Alfaro, B.

10.1101/2021.03.09.434521 — ecology — Posted on 2021-03-10

3372 Sex, age, tissue, and disease patterns of matrisome expression in GTEx transcriptome data

Nieuwenhuis, T. O.; Rosenberg, A. Z.; McCall, M. N.; Halushka, M. K.

10.1101/2021.03.09.434609 — molecular biology — Posted on 2021-03-10

3373 MEYE: Web-app for translational and real-time pupillometry

Mazziotti, R. M.; Carrara, F.; Viglione, A.; Lupori, L.; Lo Verde, L.; Benedetto, A.; Ricci, G.; Sagona, G.; Amato, G.; Pizzorusso, T.

10.1101/2021.03.09.434438 — neuroscience — Posted on 2021-03-10

3374 Structural connectome quantifies tumor invasion and predicts survival in glioblastoma patients

Wei, Y.; Li, C.; Cui, Z.; Mayrand, R. C.; Zou, J.; Wong, A. L. K. C.; Sinha, R.; Matys, T.; Schönlieb, C.-B.; Price, S. J.

10.1101/2021.03.09.434656 — neuroscience — Posted on 2021-03-10

3375 A precise and adaptive neural mechanism for predictive temporal processing in the frontal cortex

Meirhaeghe, N.; Sohn, H.; Jazayeri, M.

10.1101/2021.03.10.434831 — neuroscience — Posted on 2021-03-10

3376 Mapping of Whole-Brain Resting-State Networks with Half-Millimetre Resolution

Yun, S. D.; Pais-Roldan, P.; Palomero-Gallagher, N.; Shah, N. J.

10.1101/2021.03.09.434629 — neuroscience — Posted on 2021-03-10

3377 OsbZIP62/OsFD7, a functional ortholog of Flowering Locus D (FD), regulates floral transition and panicle development in rice

Kaur, D. A.; Nijhawan, D. A.; Yadav, M.; Khurana, D. J. P.

10.1101/2021.03.09.434543 — plant biology — Posted on 2021-03-10

3378 Bi-directional flow of the funny current (If) during the pacemaking cycle in murine sinoatrial node myocytes

Peters, C. H.; Liu, P.; Morotti, S.; Gantz, S. C.; Grandi, E.; Bean, B. P.; Proenza, C.

10.1101/2021.03.10.434820 — physiology — Posted on 2021-03-10

3379 Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes

Sun, D.; Sang, Z.; Kim, J.; Xiang, Y.; Cohen, T.; Belford, A. K.; Huet, A.; Conway, J. F.; Sun, J.; Taylor, D.; Zhang, C.; Huang, W.; Shi, Y.

10.1101/2021.03.09.434592 — biophysics — Posted on 2021-03-10

3380 A linear response theory based method for prediction of large scale protein conformational changes upon ligand binding

Punia, R.; Goel, G.

10.1101/2021.03.09.434598 — biophysics — Posted on 2021-03-10

3381 A comprehensive computational investigation into the conserved virulent proteins of Shigella sp unveils potential siRNA candidates as a new therapeutic strategy against shigellosis

Palit, P.; Chowdhury, F. T.; Sarkar, B.; Noor, S.; Kamal, M.; Noor, Z.; Siddiqua, T. J.

10.1101/2021.03.09.434519 — bioinformatics — Posted on 2021-03-10

3382 Cancer type classification in liquid biopsies based on sparse mutational profiles enabled through data augmentation and integration

Danyi, A.; Jager, M.; de Ridder, J.

10.1101/2021.03.09.434391 — bioinformatics — Posted on 2021-03-10

3383 A smoothed version of the Lassosum penalty for fitting integrated risk models

Hahn, G.; Prokopenko, D.; Lutz, S. M.; Mullin, K.; Tanzi, R.; Lange, C.

10.1101/2021.03.09.434653 — bioinformatics — Posted on 2021-03-10

3384 Trajectory inference across multiple conditions with condiments: differential topology, progression, differentiation, and expression.

Roux de Bezieux, H.; Van den Berge, K.; Street, K. N.; Dudoit, S.

10.1101/2021.03.09.433671 — bioinformatics — Posted on 2021-03-10

3385 Integrated bioinformatics analysis reveals novel key biomarkers and potential candidate small molecule drugs in gestational diabetes mellitus

Vastrad, B. M.; Vastrad, C. M.; Tengli, A. R.

10.1101/2021.03.09.434569 — bioinformatics — Posted on 2021-03-10

3386 CHIPS: A Snakemake pipeline for quality control and reproducible processing of chromatin profiling data

Taing, L.; Cousins, C.; Bai, G.; Paloma, C.; Qiu, X.; Brown, M.; Meyer, C. A.; Liu, X. S.; Long, H. W.; Tang, M.

10.1101/2021.03.09.434676 — bioinformatics — Posted on 2021-03-10

3387 End-to-end Learning of Evolutionary Models to Find Coding Regions in Genome Alignments

Mertsch, D.; Stanke, M.

10.1101/2021.03.09.434414 — bioinformatics — Posted on 2021-03-10

3388 ChexMix: A Literature Content Extraction Tool for Bioentities

Yang, H.; Park, B.; Park, J.; Lee, J.; Jang, H. S.; Lee, N.; Yoo, H.

10.1101/2021.03.09.434525 — bioinformatics — Posted on 2021-03-10

3389 Systematic evaluation of transcriptomics-based deconvolution methods and references using thousands of clinical samples

Nadel, B.; Oliva, M.; Shou, B. L.; Mitchell, K.; Ma, F.; Montoya, D. J.; Mouton, A.; Kim-Hellmuth, S.; Stranger, B.; Pellegrini, M.; Mangul, S.

10.1101/2021.03.09.434660 — bioinformatics — Posted on 2021-03-10

3390 Hierarchical semantic composition of biosimulation models using bond graphs

Shahidi, N.; Pan, M.; Safaei, S.; Tran, K.; Crampin, E. J.; Nickerson, D. P.

10.1101/2021.03.09.434672 — bioengineering — Posted on 2021-03-10

3391 Chromosomal rearrangements but no change of genes and transposable elements repertoires in an invasive forest-pathogenic fungus

Demene, A.; Laurent, B.; Cros-Arteil, S.; Boury, C.; Dutech, C.

10.1101/2021.03.09.434572 — genomics — Posted on 2021-03-10

3392 Identification of Cell-Free DNA Methylation Patterns Unique to the Human Left Ventricle as a Potential Indicator of Acute Cellular Rejection

Pattar, S.; Aleinati, M.; Iqbal, F.; Made, A.; Blais, S.; Wang, X.; Dallaire, F.; Wang, Y.; Isaac, D.; Fine, N.; Greenway, S. C.

10.1101/2021.03.10.434822 — genetics — Posted on 2021-03-10

3393 Fungal Transcription factors: Markers of genetic innovation, network rewiring and conflict between genomics and transcriptomics.

Etxebeste, O.

10.1101/2021.03.09.434684 — evolutionary biology — Posted on 2021-03-10

3394 Dynamic sampling bias and overdispersion induced by skewed offspring distributions

Okada, T.; Hallatschek, O.

10.1101/2021.03.09.434663 — evolutionary biology — Posted on 2021-03-10

3395 Comparative viral metagenomics from chicken feces and farm dust in the Netherlands

Kwok, K. T.; de Rooij, M. M. T.; Messink, A. B.; Wouters, I.; Smit, L. A. M.; Heederik, D.; Koopmans, M.; Phan, M. V.

10.1101/2021.03.09.434704 — evolutionary biology — Posted on 2021-03-10

3396 Evolutionary dynamics of the OR gene repertoire in teleost fishes: evidence of an association with changes in olfactory epithelium shape

Policarpo, M.; Bemis, K. E.; Tyler, J. C.; Metcalfe, C. J.; Laurenti, P.; Sandoz, J.-C.; Retaux, S.; Casane, D.

10.1101/2021.03.09.434524 — evolutionary biology — Posted on 2021-03-10

3397 MinION barcodes: biodiversity discovery and identification by everyone, for everyone

Srivathsan, A.; Lee, L.; Katoh, K.; Hartop, E.; Kutty, S. N.; Wong, J.; Yeo, D.; Meier, R.

10.1101/2021.03.09.434692 — ecology — Posted on 2021-03-10

3398 A neural progenitor mitotic wave is required for asynchronous axon outgrowth and morphology

Lacoste, J.; Soula, H.; Burg, A.; Audibert, A.; Darnat, P.; Gho, M.; Louvet-Vallee, S.

10.1101/2021.03.10.434802 — developmental biology — Posted on 2021-03-10

3399 Bacteriophage inhibits murine norovirus replication after co-incubation in RAW 264.7 cells

Wang, R.; Shahin, K.; Zhang, L.

10.1101/2021.03.09.434703 — microbiology — Posted on 2021-03-10

3400 The ubiquitous terpene geosmin is a warning chemical

Zaroubi, L.; Ozugergin, I.; Imfeld, A.; Mastronardi, K.; Law, C.; Gelinas, Y.; Piekny, A.; Findlay, B.

10.1101/2021.03.09.434661 — microbiology — Posted on 2021-03-10

3401 Ecophysiology of the cosmopolitan OM252 bacterioplankton (Gammaproteobacteria)

Savoie, E. R.; Lanclos, V. C.; Henson, M.; Cheng, C.; Getz, E. W.; Barnes, S. J.; LaRowe, D. E.; Rappe, M. S.; Thrash, J. C.

10.1101/2021.03.09.434695 — microbiology — Posted on 2021-03-10

3402 Effect of chronic JUUL aerosol inhalation on inflammatory states of the brain, lung, heart and colon in mice

Moshensky, A.; Brand, C.; Alhaddad, H.; Shin, J.; Masso-Silva, J. A.; Advani, I.; Gunge, D.; Sharma, A.; Mehta, S.; Jahan, A.; Nilaad, S.; Almarghalani, D.; Pham, J.; Perera, S.; Park, K.; Al-Kolla, R.; Moon, H.; Das, S.; Byun, M.; Shah, Z.; Sari, Y.; Heller Brown, J.; Crotty Alexander, L. E.

10.1101/2021.03.09.434442 — immunology — Posted on 2021-03-10

3403 Multivariate Pattern Analysis (MVPA) Reveals Distinct Neural Profiles of Frontoparietal Networks in Boys with Attention-Deficit/Hyperactivity Disorder and Boys with Persistent Depressive Disorder

Vilgis, V.; Yee, D. M.; Silk, T.; Vance, A.

10.1101/2021.03.09.434662 — neuroscience — Posted on 2021-03-10

3404 Psychomotor impairments and therapeutic implications revealed by a mutation linked with Infantile Parkinsonism-Dystonia

Aguilar, J. I.; Cheng, M. H.; Font, J.; Schwartz, A. C.; Ledwitch, K.; Duran, A.; Mabry, S. J.; Belovich, A. N.; Zhu, Y.; Carter, A. M.; Shi, L.; Kurian, M. A.; Fenollar-Ferrer, C.; Meiler, J.; Ryan, R. M.; Mchaourab, H. S.; Bahar, I.; Matthies, H. J. G.; Galli, A.

10.1101/2021.03.09.434693 — neuroscience — Posted on 2021-03-10

3405 Flow cytometry allows rapid detection of protein aggregates in cell culture and zebrafish models of spinocerebellar ataxia-3

Robinson, K. J.; Tym, M. C.; Hogan, A.; Watchon, M.; Yuan, K. C.; Plenderleith, S. K.; Don, E. K.; Laird, A. S.

10.1101/2021.03.09.434364 — neuroscience — Posted on 2021-03-10

3406 A role for glial fibrillary acidic protein (GFAP)-expressing cells in the regulation of gonadotropin-releasing hormone (GnRH) but not arcuate kisspeptin neuron output

Vanacker, C.; DeFazio, R. A.; Sykes, C. M.; Moenter, S. M.

10.1101/2021.03.10.434805 — neuroscience — Posted on 2021-03-10

3407 Electrophysiological signatures of hierarchical learning

Liu, M.; Dong, W.; Qin, S.; Verguts, T.; Chen, Q.

10.1101/2021.03.09.434666 — neuroscience — Posted on 2021-03-10

3408 Hippocampal replay reflects specific past experiences rather than a plan for subsequent choice

Gillespie, A. K.; Astudillo Maya, D. A.; Denovellis, E. L.; Liu, D. F.; Kastner, D. B.; Coulter, M. E.; Roumis, D. K.; Eden, U. T.; Frank, L. M.

10.1101/2021.03.09.434621 — neuroscience — Posted on 2021-03-10

3409 High frequency rTMS modulates functional connectivity nodes and boundaries differently in the human brain

Belov, V.; Kozyrev, V.; Singh, A.; Sacchet, M. D.; Goya-Maldonado, R.

10.1101/2021.03.09.434571 — neuroscience — Posted on 2021-03-10

3410 The nuclear ubiquitin ligase adaptor SPOP is a conserved regulator of C9orf72 dipeptide toxicity

Snoznik, C.; Medvedeva, V.; Mojsilovic-Petrovic, J.; Rudich, P.; Oosten, J.; Kalb, R. G.; Lamitina, T.

10.1101/2021.03.09.434618 — neuroscience — Posted on 2021-03-10

3411 Trophic transfer of microplastics enhances tissue accumulation of chemical additives in fish

Hasegawa, T.; Mizukawa, K.; Yeo, G. B.; Sekioka, T.; Takada, H.; Nakaoka, M.

10.1101/2021.03.09.434685 — pharmacology and toxicology — Posted on 2021-03-10

3412 Mechanism of praziquantel action at a parasitic flatworm ion channel

Park, S.-K.; Friedrich, L.; Yahya, N. A.; Rohr, C.; Chulkov, E. G.; Maillard, D.; Rippmann, F.; Spangenberg, T.; Marchant, J. S.

10.1101/2021.03.09.434291 — pharmacology and toxicology — Posted on 2021-03-10

3413 All-polymeric transient neural probe for prolonged in-vivo electrophysiological recordings

Ferlauto, L.; Vagni, P.; Fanelli, A.; Zollinger, E. G.; Monsorno, K.; Paolicelli, R. C.; Ghezzi, D.

10.1101/2021.03.09.434622 — bioengineering — Posted on 2021-03-10

3414 Anomalous low impedance for small platinum microelectrodes

Fan, B.; Robinson, J.

10.1101/2021.03.09.434678 — bioengineering — Posted on 2021-03-10

3415 Molecular mechanism underlying substrate recognition of the peptide macrocyclase PsnB

Song, I.; Kim, Y.; Yu, J.; Go, S. Y.; Lee, H. G.; Song, W. J.; Kim, S.

10.1101/2021.03.09.434688 — biochemistry — Posted on 2021-03-10

3416 Movement patterns and activity levels are shaped by the neonatal environment in Antarctic fur seal pups

Nagel, R.; Mews, S.; Adam, T.; Stainfield, C.; Fox-Clarke, C.; Toscani, C.; Langrock, R.; Forcada, J.; Hoffman, J. I.

10.1101/2021.03.09.434640 — animal behavior and cognition — Posted on 2021-03-10

3417 Automated video tracking and flight analysis show how bumblebees solve a pattern discrimination task using active vision

MaBouDi, H.; Roper, M.; Guiraud, M.; Marshall, J. A. R.; Chittka, L.

10.1101/2021.03.09.434580 — animal behavior and cognition — Posted on 2021-03-10

3418 Integrative genomics reveals paths to sex dimorphism in Salix purpurea L.

Hyden, B. L.; Carlson, C. H.; Gouker, F. E.; Schmutz, J.; Barry, K. W.; Lipzen, A.; Sharma, A.; Sandor, L.; Tuskan, G.; Feng, G.; Olson, M. S.; DiFazio, S. P.; Smart, L. B.

10.1101/2021.03.09.434562 — genomics — Posted on 2021-03-10

3419 Genome features of common vetch (Vicia sativa) in natural habitats

Shirasawa, K.; Kosugi, S.; Sasaki, K.; Ghelfi, A.; Okazaki, K.; Toyoda, A.; Hirakawa, H.; Isobe, S.

10.1101/2021.03.09.434686 — genomics — Posted on 2021-03-10

3420 A topological approach to DNA similarity analysis from 5-dimensional representation

Nguyen, D. Q. N.; Le, P. D. T.; Hu, Z.; Lin, L.

10.1101/2021.03.10.434824 — genomics — Posted on 2021-03-10

3421 Admixed Populations Improve Power for Variant Discovery and Portability in Genome-wide Association Studies

Lin, M.; Park, D. S.; Zaitlen, N. A.; Henn, B. M.; Gignoux, C. R.

10.1101/2021.03.09.434643 — genetics — Posted on 2021-03-10

3422 Genome structure of Brachionus asplanchnoidis, a Eukaryote with intrapopulation variation in genome size

Stelzer, C.-P.; Blommaert, J.; Waldvogel, A.-M.; Pichler, M.; Hecox-Lea, B.; Mark Welch, D. B.

10.1101/2021.03.09.434534 — evolutionary biology — Posted on 2021-03-10

3423 Variation in reflectance spectroscopy of European beech leaves captures phenology and biological hierarchies despite measurement uncertainties

Petibon, F.; Czyz, E. A.; Ghielmetti, G.; Hueni, A.; Kneubühler, M.; Schaepman, M. E.; Schuman, M. C.

10.1101/2021.03.09.434578 — ecology — Posted on 2021-03-10

3424 rdacca.hp: an R package for generalizing hierarchical and variation partitioning in multiple regression and canonical analysis

Lai, J.; Zou, Y.; Zhang, J.; Peres-Neto, P.

10.1101/2021.03.09.434308 — ecology — Posted on 2021-03-10

3425 Multiple resource limitations explain biomass-precipitation relationships in grasslands

Bharath, S.; Adler, P. B.; Fay, P. A.; Seabloom, E.; Hautier, Y.; Biederman, L.; Bugalho, M. N.; Caldeira, M.; Eskelinen, A.; Knops, J. M. H.; McCulley, R.; Morgan, J.; Power, S. A.; Risch, A. C.; Schuetz, M.; Stevens, C. J.; Timothy, O.; Virtanen, R.; Borer, E. T.

10.1101/2021.03.09.434527 — ecology — Posted on 2021-03-10

3426 Five years of citizen science and standardized field surveys reveal a threatened urban Eden for wild bees in Brussels, Belgium

Vereecken, N. J.; Weekers, T.; Marshall, L.; D'Haeseleer, J.; Cuypers, M.; Vanormelingen, P.; Pauly, A.; Pasau, B.; Leclercq, N.; Tshibungu, A.; Molenberg, J.-M.; De Greef, S.

10.1101/2021.03.10.434823 — ecology — Posted on 2021-03-10

3427 Tumor protein D52 (TPD52) affects cancer cell metabolism by negatively regulating AMPK.

Chen, Y.; Peng, C.; Tan, W.; Yu, J.; Zayas, J.; Peng, Y.; Lou, Z.; Pei, H.; Wang, L.

10.1101/2021.03.09.434668 — cell biology — Posted on 2021-03-10

3428 Detection of the germline specific NAC protein paralog enriched by intrinsically disordered regions in Drosophila melanogaster

Kogan, G. L.; Mikhaleva, E. A.; Olenkina, O. M.; Ryazansky, S. S.; Galzitskaya, O. V.; Abramov, Y. A.; Leinsoo, T. A.; Akulenko, N. V.; Gvozdev, V. A.

10.1101/2021.03.09.434555 — molecular biology — Posted on 2021-03-10

3429 Multiple nucleotide polymorphism DNA markers for the accurate evaluation of genetic variations

Fang, Z.; Li, L.; Zhou, J.; You, A.; Gao, L.; Li, T.; Chen, H.; Han, R.; Cui, Y.; Chen, L.; Xiao, H.; Zhang, J.; Xu, N.; Fu, X.; Zhang, J.; Li, X.; Ma, A.; Zhang, W.; Peng, H.

10.1101/2021.03.09.434561 — molecular biology — Posted on 2021-03-10

3430 Structures and function of locked conformations of SARS-CoV-2 spike

Qu, K.; Xiong, X.; Ciazynska, K. A.; Carter, A. P.; Briggs, J. A. G.

10.1101/2021.03.10.434733 — microbiology — Posted on 2021-03-10

3431 Naturally-acquired immunity in Syrian Golden Hamsters provides protection from re-exposure to emerging heterosubtypic SARS-CoV-2 variants B.1.1.7 and B.1.351

Clark, J. J.; Sharma, P.; Bentley, E.; Harding, A. C.; Kipar, A.; Neary, M.; Box, H.; Hughes, G.; Patterson, E. I.; Sharp, J.; de Oliveira, T.; Sigal, A.; Hiscox, J. A.; James, W. S.; Carroll, M. W.; Owen, A.; Stewart, J. P.

10.1101/2021.03.10.434447 — microbiology — Posted on 2021-03-10

3432 Longitudinal single-cell epitope and RNA-sequencing reveals the immunological impact of type 1 interferon autoantibodies in critical COVID-19

van der Wijst, M. G. P.; Vazquez, S. E.; Hartoularos, G. C.; Bastard, P.; Grant, T.; Bueno, R.; Lee, D. S.; Greenland, J. R.; Sun, Y.; Perez, R.; Ogorodnikov, A.; Ward, A.; Mann, S. A.; Lynch, K. L.; Yun, C.; Havlir, D. V.; Chamie, G.; Marquez, C.; Greenhouse, B.; Lionakis, M. S.; Norris, P. J.; Dumont, L. J.; Kelly, K.; Zhang, P.; Zhang, Q.; Gervais, A.; Le Voyer, T.; Whatley, A.; Si, Y.; Byrne, A.; Combes, A. J.; Arkal, A.; Song, Y. S.; Fragiadakis, G. K.; UCSF COMET consortium, ; Kangelaris, K.; Calfee, C. S.; Erle, D. J.; Hendrickson, C.; Krummel, M. F.; Woodruff, P. G.; Langelier, C. R.;

10.1101/2021.03.09.434529 — immunology — Posted on 2021-03-10

3433 Nanoscopic dopamine transporter distribution and conformation are inversely regulated by excitatory drive and D2-autoreceptor activity

Lycas, M. D.; Ejdrup, A. L.; Sorensen, A. T.; Haahr, N. O.; Jorgensen, S. H.; Guthrie, D. A.; Stoier, J. F.; Werner, C.; Newman, A. H.; Sauer, M.; Herborg, F. H.; Gether, U.

10.1101/2021.03.09.434538 — neuroscience — Posted on 2021-03-10

3434 Task switching costs contribute to the apparent speeding of multisensory reaction times

Albat, M.; Hautmann, J.; Kayser, C.; Molinski, J.; Ulku, S.

10.1101/2021.03.09.434565 — neuroscience — Posted on 2021-03-10

3435 Distinct foraging strategies generated by single-action behavioural flexibility

Quach, K. T.; Chalasani, S. H.

10.1101/2021.03.09.434602 — neuroscience — Posted on 2021-03-10

3436 Dorsal skull meningeal lymphatic vessels drain blood-solutes after intracerebral hemorrhage

Virenque, A.; Balin, R.; Noe, F. M.

10.1101/2021.03.09.434530 — neuroscience — Posted on 2021-03-10

3437 Social learning about rewards: how information from others helps to adapt to changing environment

Winiarski, M.; Borowska, J.; Wolyniak, M. R.; Jedrzejewska-Szmek, J.; Kondrakiewicz, L.; Mankiewicz, L.; Wojcik, D. K.; Puscian, A.; Knapska, E.

10.1101/2021.03.09.434563 — neuroscience — Posted on 2021-03-10

3438 Inner hair cell dysfunction in Klhl18 mutant mice leads to low frequency progressive hearing loss

Ingham, N. J.; Banafshe, N.; Panganiban, C. H.; Crunden, J. L.; Chen, J.; Steel, K. P.

10.1101/2021.03.09.434536 — neuroscience — Posted on 2021-03-10

3439 Location, location, location- choice of Voxel-Based Morphometry processing pipeline drives variability in the location of neuroanatomical brain markers

Zhou, X.; Wu, R.; Zeng, Y.; Qi, Z.; Ferraro, S.; Yao, S.; Kendrick, K. M.; Becker, B.

10.1101/2021.03.09.434531 — neuroscience — Posted on 2021-03-10

3440 A conversion from slow to fast memory in response to passive motion

Javidialsaadi, M.; Albert, S. T.; Wang, J.

10.1101/2021.03.09.434594 — neuroscience — Posted on 2021-03-10

3441 iEC7871 Quercus suber model: the first multi-tissue diel cycle genome-scale metabolic model of a woody tree

Cunha, E.; Silva, M.; Chaves, I.; Demirci, H.; Lagoa, D.; Lima, D.; Rocha, M.; Rocha, I.; Dias, O.

10.1101/2021.03.09.434537 — systems biology — Posted on 2021-03-10

3442 Structure and dynamics of the SARS-CoV-2 envelope protein monomer

Kuzmin, A.; Orekhov, P.; Astashkin, R.; Gordeliy, V.; Gushchin, I.

10.1101/2021.03.10.434722 — biophysics — Posted on 2021-03-10

3443 The combined treatment of Molnupiravir and Favipiravir results in a marked potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model

Abdelnabi, R.; Foo, C. S.; Kaptein, S. J. F.; Zhang, X.; Langendries, L.; Vangeel, L.; Breuer, J.; Pang, J.; Williams, R.; Vergote, V.; Heylen, E.; Leyssen, P.; Dallmeier, K.; Coelmont, L.; Jochmans, D.; Chatterjee, A. K.; De Jonghe, S.; Weynand, B.; Neyts, J.

10.1101/2020.12.10.419242 — microbiology — Posted on 2021-03-10

3444 Discovery of re-purposed drugs that slow SARS-CoV-2 replication in human cells

Pickard, A.; Calverley, B. C.; Chang, J.; Garva, R.; Lu, Y.; Kadler, K. E.

10.1101/2021.01.31.428851 — immunology — Posted on 2021-03-10

3445 Effects of tDCS Dose and Electrode Montage on regional cerebral blood flow and motor behavior

Shinde, A.; Lerud, K. D.; Munsch, F.; Alsop, D.; Schlaug, G.

10.1101/2021.02.02.429369 — neuroscience — Posted on 2021-03-10

3446 Cheetah: a computational toolkit for cybergenetic control

Pedone, E.; de Cesare, I.; Zamora, C.; Haener, D.; Postiglione, L.; La Regina, A.; Shannon, B.; Savery, N.; Grierson, C. S.; di Barnardo, M.; Gorochowski, T. E.; Marucci, L.

10.1101/2020.06.25.171751 — synthetic biology — Posted on 2021-03-10

3447 Highly-parallel microfluidics-based force spectroscopy on single cytoskeletal motors

Urbanska, M.; Lüdecke, A.; Walter, W. J.; van Oijen, A. M.; Duderstadt, K. E.; Diez, S.

10.1101/2020.08.11.245910 — biophysics — Posted on 2021-03-10

3448 The timing of human adaptation from Neanderthal introgression

Yair, S.; Lee, K. M.; Coop, G.

10.1101/2020.10.04.325183 — evolutionary biology — Posted on 2021-03-10

3449 Movement signaling in ventral pallidum and dopaminergic midbrain is gated by behavioral state in singing birds

Chen, R.; Gadagkar, V.; Roeser, A. C.; Puzerey, P. A.; Goldberg, J. H.

10.1101/2020.06.22.164814 — neuroscience — Posted on 2021-03-10

3450 Genome-Wide Covariation in SARS-CoV-2

Cresswell-Clay, E. C.; Periwal, V.

10.1101/2021.03.08.434363 — genomics — Posted on 2021-03-10

3451 Development and pre-clinical evaluation of Newcastle disease virus-vectored SARS-CoV-2 intranasal vaccine candidate

Fernandez-Diaz, M.; Calderon, K.; Rojas-Neyra, A.; Vakharia, V. N.; Choque-Guevara, R.; Montalvan, A.; Poma-Acevedo, A.; Rios-Matos, D.; Agurto-Arteaga, A.; Cauti-Mendoza, M. D. G.; Perez-Martinez, N.; Isasi-Rivas, G.; Tataje-Lavanda, L.; Palomino, M.; Bailon, H.; Sernaque-Aguilar, Y.; Ygnacio-Aguire, F.; Criollo-Orozco, M.; Huaccachi-Gonzalez, E.; Delgado-Ccancce, E.; Villanueva-Perez, D.; Montesinos-Millan, R.; Gutierrez-Manchay, K.; Pauyac-Antezana, K.; Ramirez-Ortiz, I.; Quinones-Garcia, S.; Cauna-Orocollo, Y.; Vallejos-Sanchez, K.; Rios-Angulo, A. A.; Nunez-Fernandez, D.; Salguedo-Bohorqu

10.1101/2021.03.07.434276 — immunology — Posted on 2021-03-10

3452 The M1 aminopeptidase NPEPPS is a novel regulator of cisplatin sensitivity

10.1101/2021.03.04.433676 — cancer biology — Posted on 2021-03-10

3453 Size-dependent eco-evolutionary feedbacks in fisheries

Edeline, E.; Loeuille, N.

10.1101/2020.04.03.022905 — ecology — Posted on 2021-03-10

3454 Single paternal Dexamethasone challenge programs offspring metabolism and reveals circRNAs as novel candidates in RNA-mediated inheritance

Gapp, K.; Parada, G. E.; Gross, F.; Corcoba, A.; Grau, E.; Hemberg, M.; Bohacek, J.; Miska, E. A.

10.1101/2021.02.10.429888 — developmental biology — Posted on 2021-03-10

3455 I knew that! Response-based Outcome Predictions and Confidence Regulate Feedback Processing and Learning

Froemer, R.; Nassar, M. R.; Bruckner, R.; Stuermer, B.; Sommer, W.; Yeung, N.

10.1101/442822 — neuroscience — Posted on 2021-03-10

3456 MRI of Capn15 knockout mice and analysis of Capn15 distribution reveal possible roles in brain development and plasticity

Zha, C.; Farah, C. A.; Fonov, V.; Rudko, D.; Sossin, W. S.

10.1101/763888 — neuroscience — Posted on 2021-03-10

3457 Hydrogen peroxide modulates lignin and silica deposits in sorghum roots

Zexer, N.; Elbaum, R.

10.1101/2021.02.01.429181 — plant biology — Posted on 2021-03-10

3458 IWS1 phosphorylation by AKT3 controls nuclear export of type I IFN mRNAs and sensitivity to oncolytic viral infection, by regulating the alternative RNA splicing of U2AF2.

Laliotis, G. I.; Kenney, A.; Chavdoula, E.; Orlacchio, A.; Kaba, A. K.; La Ferlita, A.; Anastas, V.; Tsatsanis, C.; Beane, J. D.; Sehgal, L.; Coppola, V.; Yount, J. S.; Tsichlis, P. N.

10.1101/2020.12.26.424461 — cancer biology — Posted on 2021-03-10

3459 IWS1 phosphorylation promotes cell proliferation and predicts poor prognosis in EGFR mutant lung adenocarcinoma patients, through the cell cycle-regulated U2AF2 RNA splicing.

Laliotis, G. I.; Chavdoula, E.; Paraskevopoulou, M. D.; Kaba, A. D.; La Ferlita, A.; Singh, S.; Anastas, V.; Alaimo, S.; Orlacchio, A.; Nair, K. A.; Taraslia, V.; Vlachos, I.; Capece, M.; Hatzigeorgiou, A.; Palmieri, D. I.; Tsatsanis, C.; Sehgal, L.; Carbone, D. P.; Coppola, V.; Tsichlis, P. N.

10.1101/2020.07.14.195297 — cancer biology — Posted on 2021-03-10

3460 HLA-SPREAD: A Natural Language Processing based resource for curating HLA association from PubMed abstracts

Dholakia, D.; Kalra, A.; Misir, B. R.; Kanga, U.; Mukerji, M.

10.1101/2021.01.05.425409 — bioinformatics — Posted on 2021-03-10

3461 immuneML: an ecosystem for machine learning analysis of adaptive immune receptor repertoires

10.1101/2021.03.08.433891 — bioinformatics — Posted on 2021-03-10

3462 A multi-phase multi-objective dynamic genome-scale model shows different redox balancing among yeast species in fermentation

Henriques, D.; Minebois, R.; Mendonza, S. N.; Macias, L. G.; Perez-Torrado, R.; Barrio, E.; Teusink, B.; Querol, A.; Balsa-Canto, E.

10.1101/2021.03.08.434513 — systems biology — Posted on 2021-03-10

3463 Dual regulation of the actin cytoskeleton by CARMIL-GAP

Jung, G.; Pan, M.; Alexander, C.; Jin, T.; Hammer, J.

10.1101/2021.03.09.434482 — cell biology — Posted on 2021-03-10

3464 Function of AtPGAP1 in GPI anchor lipid remodeling and transport to the cell surface of GPI-anchored proteins

Bernat-Silvestre, C.; Sanchez-Simarro, J.; Ma, Y.; Johnson, K. L.; Aniento, F.; Marcote, M. J.

10.1101/2021.03.09.434604 — cell biology — Posted on 2021-03-10

3465 Snowball Earths, population bottlenecks, and the evolution of marine photosynthetic bacteria

Zhang, H.; Sun, Y.; Zeng, Q.; Crowe, S. A.; Luo, H.

10.1101/2020.11.24.395392 — microbiology — Posted on 2021-03-10

3466 Ecological relevance of abundant and rare taxa in a highly-diverse elastic hypersaline microbial mat, using a small-scale sampling

Espinosa-Asuar, L.; Monroy, C.; Madrigal-Trejo, D.; Navarro-Miranda, M.; Sanchez-Perez, J.; Munoz, J.; Villar, J. D.; Cifuentes, J.; Kalambokidis, M.; Esquivel-Hernandez, D. A.; Viladomat, M.; Escalante-Hernandez, A. E.; Velez, P.; Figueroa, M.; Ramirez Barahona, S.; Gasca-Pineda, J.; Eguiarte, L. E.; Souza, V.

10.1101/2021.03.04.433984 — microbiology — Posted on 2021-03-10

3467 Limited metacognitive access to one's own facial expressions

Ciston, A. B.; Forster, C.; Brick, T. R.; Kühn, S.; Verrel, J.; Filevich, E.

10.1101/2021.03.08.434069 — neuroscience — Posted on 2021-03-10

3468 Underground Heterosis for Melons Yield

Dafna, A.; Halperin, I.; Oren, E.; Isaacson, T.; Tzuri, G.; Meir, A.; Schaffer, A. A.; Burger, J.; Tadmor, Y.; Buckler, E. S.; Gur, A.

10.1101/2021.03.04.434025 — plant biology — Posted on 2021-03-10

3469 Cinnamoyl-CoA Reductase 1 (CCR1) and CCR2 Function Divergently in Tissue Lignification, Flux Control and Cross-talk with Glucosinolate Pathway in Brassica napus

Yin, N.; Li, B.; Liu, X.; Liang, Y.; Lian, J.-P.; Xue, Y.; Qu, C.; Lu, K.; Wei, L.; Wang, R.; Li, J.; Chai, Y.-R.

10.1101/2021.03.01.433400 — plant biology — Posted on 2021-03-10

3470 Optimized cryo-EM data acquisition workflow by sample thickness determination

Rheinberger, J.; Oostergetel, G.; Resch, G. P.; Paulino, C.

10.1101/2020.12.01.392100 — biophysics — Posted on 2021-03-10

3471 Forward variable selection improves the power of random forest for high- dimensional microbiome data

Dang, T.; Kishino, H.

10.1101/2020.10.29.361360 — bioinformatics — Posted on 2021-03-10

3472 HLA-SPREAD: A Natural Language Processing based resource for curating HLA association from PubMed abstracts

Mukerji, M.; Dholakia, D.; Kalra, A.; Kanga, U.; Misir, B. R.

10.1101/2021.01.05.425409 — bioinformatics — Posted on 2021-03-10

3473 Cell type-aware analysis of RNA-seq data

Jin, C.; Chen, M.; Lin, D.; Sun, W.

10.1101/2020.07.13.201061 — bioinformatics — Posted on 2021-03-10

3474 Make Interactive Complex Heatmaps in R

Gu, Z.; Huebschmann, D.

10.1101/2021.03.08.434289 — bioinformatics — Posted on 2021-03-10

3475 Rbec: a tool for analysis of amplicon sequencing data from synthetic microbial communities

Zhang, P.; Spaepen, S.; Bai, Y.; Hacquard, S.; Garrido-Oter, R.

10.1101/2021.01.15.426834 — bioinformatics — Posted on 2021-03-10

3476 3D-printed drug testing platform based on a 3D model of aged human skeletal muscle

Mestre, R.; Garcia, N.; Patino, T.; Guix, M.; Fuentes, J.; Valerio-Santiago, M.; Alminana, N.; Sanchez, S.

10.1101/2020.06.18.158659 — bioengineering — Posted on 2021-03-10

3477 Reference plasmid pHXB2_D is an HIV-1 molecular clone that exhibits identical LTRs and a single integration site indicative of an HIV provirus

Gener, A. R.; Foley, B. T.; Hyink, D. P.; Klotman, P. E.

10.1101/611848 — genomics — Posted on 2021-03-10

3478 Cost-effective long-read assembly of a hybrid Formica aquilonia x Formica polyctena wood ant genome from a single haploid individual

Nouhaud, P.; Beresford, J.; Kulmuni, J.

10.1101/2021.03.09.434597 — genomics — Posted on 2021-03-10

3479 Multi-influential interactions alters behaviour and cognition through six main biological cascades in Down syndrome mouse models

Duchon, A.; Muniz Moreno, M. d. M.; Martin Lorenzo, S.; Silva de Souza, M. P.; Chevalier, C.; Nalesso, V.; Meziane, H.; Loureiro de Sousa, P.; Noblet, V.; Armspach, J.-P.; Brault, V.; Herault, Y.

10.1101/2020.07.08.193136 — genetics — Posted on 2021-03-10

3480 Diversification, Spread, and Admixture of Octoploid Strawberry in the Western Hemisphere

Bird, K. A.; Hardigan, M. A.; Ragsdale, A. P.; Knapp, S. J.; VanBuren, R.; Edger, P. P.

10.1101/2021.03.08.434492 — evolutionary biology — Posted on 2021-03-10

3481 Ancient genomes reveal hybridisation between extinct short-faced bears and the extant spectacled bear (Tremarctos ornatus)

Salis, A. T.; Gower, G.; Schubert, B. W.; Soibelzon, L. H.; Heiniger, H.; Prieto, A.; Prevosti, F. J.; Meachen, J.; Cooper, A.; Mitchell, K. J.

10.1101/2021.02.05.429853 — evolutionary biology — Posted on 2021-03-10

3482 Quantifying year-round nocturnal bird migration with a fluid dynamics model

Nussbaumer, R.; Bauer, S.; Benoit, L.; Mariethoz, G.; Liechti, F.; Schmid, B.

10.1101/2020.10.13.321844 — ecology — Posted on 2021-03-10

3483 Hydraulic diversity stabilizes productivity in a large-scale subtropical tree biodiversity experiment

Schnabel, F.; Liu, X.; Kunz, M.; Barry, K. E.; Bongers, F. J.; Bruelheide, H.; Fichtner, A.; Härdtle, W.; Li, S.; Pfaff, C.-T.; Schmid, B.; Schwarz, J. A.; Tang, Z.; Yang, B.; Bauhus, J.; von Oheimb, G.; Ma, K.; Wirth, C.

10.1101/2021.01.06.425434 — ecology — Posted on 2021-03-10

3484 Lung organoids and microplastic fibers: a new exposure model for emerging contaminants

Winkler, A. S.; Santo, N.; Madasci, L.; Cherubini, A.; Rusconi, F.; Rosso, L.; Tremolada, P.; Lazzari, L.; Bacchetta, R.

10.1101/2021.03.07.434247 — molecular biology — Posted on 2021-03-10

3485 Visual QC Protocol for FreeSurfer Cortical Parcellations from Anatomical MRI

Raamana, P. R.; Theyers, A.; Selliah, T.; Bhati, P.; Arnott, S. R.; Hassel, S.; Nanayakkara, N. D.; Scott, C. J. M.; Harris, J.; Zamyadi, M.; Lam, R. W.; Milev, R.; Mueller, D. J.; Rotzinger, S.; Frey, B. N.; Kennedy, S. H.; Black, S. E.; Lang, A.; Masellis, M.; Symons, S.; Bartha, R.; MacQueen, G. M.; CANBIND Investigator Team, ; ONDRI Study Group, ; Strother, S. C.

10.1101/2020.09.07.286807 — neuroscience — Posted on 2021-03-10

3486 Combining tensor decomposition and time warping models for multi-neuronal spike train analysis

Williams, A. H.

10.1101/2020.03.02.974014 — neuroscience — Posted on 2021-03-10

3487 The action of Con-ikot-ikot toxin on single AMPA-type glutamate receptors

Baranovic, J.; Braunbeck, S.; Zaki, N.; Minniberger, S.; Chebli, M.; Plested, A. J.

10.1101/2021.02.19.432041 — neuroscience — Posted on 2021-03-10

3488 Endogenous retrovirus rewired the gene regulatory network shared between primordial germ cells and naïve pluripotent cells in hominoids

Ito, J.; Seita, Y.; Kojima, S.; Parrish, N. F.; Sasaki, K.; Sato, K.

10.1101/2021.03.09.434541 — genetics — Posted on 2021-03-10

3489 In situ maturated early-stage human induced pluripotent stem cell-derived cardiomyocytes improve cardiac function by enhancing segmentary contraction in infarcted rats

Biagi, D.; Fantozzi, E. T.; Campos-Oliveira, J. C.; Naghetini, M. V.; Ribeiro, A. F.; Rodrigues, S.; Ogusuku, I.; Vanderlinde, R.; Christie, M. L. A.; Mello, D. B.; Campos de Carvalho, A. C.; Valadares, M.; Cruvinel, E.; Dariolli, R.

10.1101/2021.03.09.434658 — physiology — Posted on 2021-03-10

3490 Towards a broad-spectrum antiviral, the myristoyltransferase inhibitor IMP-1088 suppresses viral replication - the Yellow fever NS5 is myristoylated

Bodem, J.; Immerheiser, M.; Zimniak, M.; Hilpert, H.; Geiger, N.; König, E.-M.

10.1101/2021.03.09.434547 — microbiology — Posted on 2021-03-09

3491 Measles virus exits human airway epithelia via infectious center sloughing

Hippee, C.; Singh, B.; Thurman, A.; Cooney, A.; Pezzulo, A.; Cattaneo, R.; Sinn, P. L.

10.1101/2021.03.09.434554 — microbiology — Posted on 2021-03-09

3492 Nanopore electro-osmotic trap for the label-free study of single proteins and their conformations

Schmid, S.; Stoemmer, P.; Dietz, H.; Dekker, C.

10.1101/2021.03.09.434634 — biophysics — Posted on 2021-03-09

3493 Prioritization of regulatory variants with tissue-specific function in the non-coding regions of human genome

Dong, S.; Boyle, A. P.

10.1101/2021.03.09.434619 — bioinformatics — Posted on 2021-03-09

3494 RS-FISH: Precise, interactive and scalable smFISH spot detection using Radial Symmetry

Bahry, E.; Breimann, L.; Epstein, L.; Kolyvanov, K.; Harrington, K.; Lionnet, T.; Preibisch, S.

10.1101/2021.03.09.434205 — bioinformatics — Posted on 2021-03-09

3495 Effects of invasion level of Prosopis juliflora on native species diversity and regeneration in Afar region, Northeast Ethiopia

Gemeda, W. S.; wakshum shiferaw,

10.1101/2021.03.09.434549 — ecology — Posted on 2021-03-09

3496 Synchronization Temperature Determines the Location of RSV Fusion During Entry in Cultured Cells

Cadena-Cruz, C. C.; De-Avila-Arias, M. C.; Costello, H. M.; Hurtado-Gomez, L. V.; Martinez-De-La-Rosa, W.; Macchia-Ceballos, G. C.; Rosales-Rada, W.; Valencia-Villa, G. C.; Villalba-Amaris, P. C.; Naeimi Kararoudi, M.; Peeples, M. E.; San Juan Vergara, H. G.

10.1101/2021.03.09.434545 — microbiology — Posted on 2021-03-09

3497 Meta-analytic connectivity modelling of deception-related brain regions

Meier, S. K.; Ray, K. L.; Mastan, J. C.; Salvage, S. R.; Robin, D. A.

10.1101/2021.03.09.434551 — neuroscience — Posted on 2021-03-09

3498 Mapping Complex Brain Torque Components and Their Genetic and Phenomic Architecture in 24,112 healthy individuals

Zhao, L.; Matloff, W.; Shi, Y.; Cabeen, R. P.; Toga, A. W.

10.1101/2021.03.09.434625 — neuroscience — Posted on 2021-03-09

3499 Remote teaching versus blended learning: exploring discourse richness and learning effectiveness

Rodrigues Cintra Armellini, B.; La Luna, A.; Bueris, V.; Pinto de Almeida, A.; Moraes Tamais, A.; Krzyzanowski Junior, F.; Hasten Reiter, V. S.; Lellis-Santos, C.; Cafe Ferreira, R. d. C.

10.1101/2021.03.09.434548 — scientific communication and education — Posted on 2021-03-09

3500 Mapping of Quantitative Trait Locus (QTLs) that contribute to Drought Tolerance in a Recombinant Inbred Line Population of horsegram (Macrotyloma uniflorum)

Katoch, M.; Chahota, R.

10.1101/2021.03.09.434553 — plant biology — Posted on 2021-03-09

3501 Mutations in a barley cytochrome P450 gene enhances pathogen induced programmed cell death and cutin layer instability

Ameen, G.; Solanki, S.; Sager-Bittara, L.; Richards, J.; Tamang, P.; Friesen, T.; Brueggeman, R.

10.1101/2021.03.09.434546 — plant biology — Posted on 2021-03-09

3502 FKBP5 expression is related to HPA flexibility and the capacity to cope with stressors in the house sparrow

Zimmer, C.; Hanson, H. E.; Martin, L. B.

10.1101/2021.03.09.434659 — physiology — Posted on 2021-03-09

3503 Dynamics of Florida milk production and total phosphate in Lake Okeechobee

Park, J.; Saberski, E.; Stabenau, E.; Sugihara, G.

10.1101/2021.03.09.434552 — biochemistry — Posted on 2021-03-09

3504 A role for the Erk MAPK pathway in modulating SAX-7/L1CAM-dependent locomotion in Caenorhabditis elegans

Moseley-Alldredge, M.; Sheoran, S.; Yoo, H.; O'Keefe, C.; Richmond, J. E.; Chen, L.

10.1101/2021.03.09.434630 — genetics — Posted on 2021-03-09

3505 Expression and protein sequence analyses of zebrafish impg2a and impg2b, two proteoglycans of the interphotoreceptor matrix

Castellini, M. E.; Spagnolli, G.; Biasini, E.; Casarosa, S.; Messina, A.

10.1101/2021.03.09.434550 — developmental biology — Posted on 2021-03-09

3506 Topaz1, an essential gene for murine spermatogenesis, down-regulates the expression of many testis-specific long non-coding RNAs.

Chadourne, M.; Poumerol, E.; Jouneau, L.; Passet, B.; Castille, J.; Sellem, E.; Pailhoux, E.; MANDON-PEPIN, B.

10.1101/2021.03.09.434544 — developmental biology — Posted on 2021-03-09

3507 Balance between extracellular matrix production and macrophage survival by a Salmonella-specific SPI-2 encoded transcription factor

Echarren, M. L.; Figueroa, N. R.; Vitor-Horen, L.; Pucciarelli, M. G.; García-del Portillo, F.; Soncini, F. C.

10.1101/2021.03.09.434593 — microbiology — Posted on 2021-03-09

3508 No influence of antibiotic on locomotion in Drosophila nigrosparsa after recovery, but influence on microbiome, possibly mediating wing-morphology change

Weiland, S. O.; Detcharoen, M.; Schlick-Steiner, B. C.; Steiner, F. M.

10.1101/2021.03.09.434651 — microbiology — Posted on 2021-03-09

3509 WNK1 Enhances Migration and Invasion in Breast Cancer Models

Jaykumar, A. B.; Jung, J.; Parida, P.; Dang, T. T.; Grzemska, M.; Earnest, S.; Wichaidit, C.; Goldsmith, E. J.; Pearson, G. W.; Malladi, S.; Cobb, M. H.

10.1101/2021.03.09.434610 — cancer biology — Posted on 2021-03-09

3510 Site-specific steric control of SARS-CoV-2 spike glycosylation

Allen, J. D.; Chawla, H.; Samsudin, F.; Zuzic, L.; Shivgan, A. T.; Watanabe, Y.; He, W.-T.; Callaghan, S.; Song, G.; Yong, P.; Brouwer, P. J. M.; Song, Y.; Cai, Y.; Duyvesteyn, H. M. E.; Malinauskas, T.; Kint, J.; Pino, P.; Wurm, M. J.; Frank, M.; Chen, B.; Stuart, D. I.; Sanders, R. W.; Andrabi, R.; Burton, D. R.; Li, S.; Bond, P. J.; Crispin, M.

10.1101/2021.03.08.433764 — biochemistry — Posted on 2021-03-09

3511 KDM6A knockout in human iPSCs alters the genome-wide histone methylation profile at active and poised enhancers, activating expression of ectoderm gene expression pathways.

Maurya, S. S.; Yang, W.; Zhang, Q.; Erdmann-Gilmore, P.; Bystry, A.; Townsend, R.; Druley, T. E.

10.1101/2021.03.09.434633 — genomics — Posted on 2021-03-09

3512 Generation of human blastocyst-like structures from pluripotent stem cells

Fan, Y.; Min, Z.-Y.; Alsolami, S.; Zhong, C.-Q.; Ma, Z.-L.; Zhong, K.; Pei, W.-D.; Zhang, P.-Y.; Kang, X.-J.; Zhang, Y.-Y.; Zhu, H.-Y.; Li, M.; Yu, Y.

10.1101/2021.03.09.434313 — developmental biology — Posted on 2021-03-09

3513 Niche signals regulate continuous transcriptional states in hematopoietic stem cells

Fast, E. M.; Sporrij, A.; Manning, M.; Rocha, E. L.; Yang, S.; Zhou, Y.; Guo, J.; Baryawno, N.; Barkas, N.; Scadden, D.; Camargo, F.; Zon, L. I.

10.1101/2021.03.09.430613 — developmental biology — Posted on 2021-03-09

3514 FLAgellum Member 8 modulates extravascular trypanosome distribution in the mammalian host

Calvo Alvarez, E.; TRAVAILLE, C.; Crouzols, A.; Rotureau, B.

10.1101/2021.01.08.425862 — microbiology — Posted on 2021-03-09

3515 Local association of Trypanosoma cruzi chronic infection foci and enteric neuropathic lesions at the tissue micro-domain scale

Khan, A. A.; Langston, H. C.; Costa, F. C.; Olmo, F.; Taylor, M. C.; McCann, C. J.; Kelly, J. M.; Lewis, M. D.

10.1101/2021.03.09.434577 — microbiology — Posted on 2021-03-09

3516 Mechanisms of transforming DNA uptake to the periplasm of Bacillus subtilis

Hahn, J.; De Santis, M.; Dubnau, D.

10.1101/2021.03.09.434615 — microbiology — Posted on 2021-03-09

3517 Insights into the controls on metabolite distributions along a latitudinal transect of the western Atlantic Ocean

Johnson, W. M.; Kido Soule, M. C.; Longnecker, K.; Bhatia, M. P.; Hallam, S. J.; Lomas, M. W.; Kujawinski, E. B.

10.1101/2021.03.09.434501 — microbiology — Posted on 2021-03-09

3518 Determination of dsRNA interactome upon Sindbis virus infection in human cells identifies SFPQ as a critical proviral factor

Girardi, E.; Messmer, M.; Lopez, P.; Fender, A.; Chicher, J.; Chane-Woon-Ming, B.; Hammann, P.; Pfeffer, S.

10.1101/2021.03.09.434591 — microbiology — Posted on 2021-03-09

3519 The FDA-approved drug cobicistat synergizes with remdesivir to inhibit SARS-CoV-2 replication

Shytaj, I. L.; Fares, M.; Lucic, B.; Gallucci, L.; Tolba, M. M.; Zimmermann, L.; Ayoub, A. T.; Cortese, M.; Neufeldt, C. J.; Laketa, V.; Chlanda, P.; Fackler, O. T.; Boulant, S.; Bartenschlager, R.; Stanifer, M.; Savarino, A.; Lusic, M.

10.1101/2021.03.09.434219 — microbiology — Posted on 2021-03-09

3520 Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas

Parekh, U.; McDonald, D.; Dailamy, A.; Wu, Y.; Cordes, T.; Zhang, K.; Tipps, A.; Metallo, C.; Mali, P.

10.1101/2021.03.09.434648 — systems biology — Posted on 2021-03-09

3521 High resolution structure of the membrane embedded skeletal muscle ryanodine receptor

Melville, Z.; Kim, K.; Clarke, O. B.; Marks, A. R.

10.1101/2021.03.09.434632 — biophysics — Posted on 2021-03-09

3522 COVIDrugNet: a network-based web tool to investigate the drugs currently in clinical trial to contrast COVID-19

Menestrina, L.; Cabrelle, C.; Recanatini, M.

10.1101/2021.03.05.433897 — bioinformatics — Posted on 2021-03-09

3523 A recombinant ACE2 Triple Decoy that traps and neutralizes SARS-CoV-2 shows enhanced affinity for highly transmissible SARS-CoV-2 variants

Tanaka, S.; Nelson, G.; Olson, A.; Buzko, O.; Higashide, W.; Shin, A.; Gonzales, M.; Taft, J.; Patel, R. S.; Buta, S.; Martin-Fernandez, M.; Bogunovic, D. S.; Spilman, P. R.; Niazi, K.; Rabizadeh, S.; Soon-Shiong, P.

10.1101/2021.03.09.434641 — bioengineering — Posted on 2021-03-09

3524 In vitro rapid inactivation of SARS-CoV-2 by visible light photocatalysis using boron-doped bismuth oxybromide

Ling, L.; Carletti, T.; Cheng, Z.; Wang, R.; Ren, Y.; Westerhoff, P.; Shang, C.; Marcello, A.; Chen, S.

10.1101/2021.03.09.434359 — bioengineering — Posted on 2021-03-09

3525 An optogenetic tool to raise intracellular pH in single cells and drive localized membrane dynamics

Donahue, C. E.; Siroky, M. D.; White, K. A.

10.1101/2021.03.09.434608 — biochemistry — Posted on 2021-03-09

3526 The role of claw colouration in fiddler crabs' mate choice: Private communication channel or handicap?

Silva, D. J. A.; Erickson, M. F.; Guidi, R. d. S.; Pessoa, D. M. A.

10.1101/2021.02.06.430085 — animal behavior and cognition — Posted on 2021-03-09

3527 Adaptive evolution of Moniliophthora PR-1 proteins towards its pathogenic lifestyle

Vasconcelos, A. A.; Jose, J.; Tokimatu Filho, P. M.; Camargo, A. P.; Teixeira, P. J. P. L.; Thomazella, D. P. T.; Prado, P. F. V.; Fiorin, G. L.; Carazzolle, M. F.; Pereira, G. A. G.; Baroni, R. M.

10.1101/2021.03.07.434232 — evolutionary biology — Posted on 2021-03-09

3528 Polycomb suppresses a female gene regulatory network to ensure testicular differentiation

Maezawa, S.; Yukawa, M.; Hasegawa, K.; Sugiyama, R.; Hu, M.; Vidal, M.; Koseki, H.; Barski, A.; DeFalco, T.; Namekawa, S. H.

10.1101/2021.01.19.427322 — developmental biology — Posted on 2021-03-09

3529 SPACE exploration of RNA-binding proteins as major chromatin components

Rafiee, M.-r.; Zagalak, J.; Sidorov, S.; Ule, J.; Luscombe, N. M.

10.1101/2020.07.13.200212 — molecular biology — Posted on 2021-03-09

3530 The gene expression profile of the song control nucleus HVC shows sex specificity, hormone responsiveness, and species specificity among songbirds

Ko, M.-C.; Frankl-Vilches, C.; Bakker, A.; Gahr, M.

10.1101/2021.02.28.432133 — molecular biology — Posted on 2021-03-09

3531 Quantitative proteomics of hamster lung tissues infected with SARS-CoV-2 reveal host-factors having implication in the disease pathogenesis and severity

Suresh, V.; Mohanty, V.; Avula, K.; Ghosh, A.; Singh, B.; Reddy, R. R. K.; Suryawanshi, A. R.; Raghav, S.; Chattopadhyay, S.; Prasad, P.; Swain, R. K.; Dash, R.; Parida, A.; Syed, G. H.; Senapati, S.

10.1101/2021.03.09.434371 — microbiology — Posted on 2021-03-09

3532 Reducing phenotypic instabilities of microbial population during continuous cultivation based on cell switching dynamics

Nguyen, T. M.; Telek, S.; Zicler, A.; Martinez, J. A.; Zacchetti, B.; Kopp, J.; Slouka, C.; Herwig, C.; Gruenberger, A.; Frank, D.

10.1101/2021.01.13.426484 — microbiology — Posted on 2021-03-09

3533 c-Myc plays a key role in IFN-γ induced persistence of Chlamydia trachomatis

Vollmuth, N.; Janaki-Raman, S.; Schlicker, L.; Kurmasheva, N.; Schmitz, W.; Schulze, A.; Rudel, T.; Rajeeve, K.

10.1101/2021.03.09.433696 — microbiology — Posted on 2021-03-09

3534 Systemic Tissue and Cellular Disruption from SARS-CoV-2 Infection revealed in COVID-19 Autopsies and Spatial Omics Tissue Maps

Park, J.; Foox, J.; Hether, T.; Danko, D.; Warren, S.; Kim, Y.; Reeves, J.; Butler, D. J.; Mozsary, C.; Rosiene, J.; Shaiber, A.; Afshinnekoo, E.; MacKay, M.; Bram, Y.; Chandar, V.; Geiger, H.; Craney, A.; Velu, P.; Melnick, A. M.; Hajirasouliha, I.; Beheshti, A.; Taylor, D.; Saravia-Butler, A.; Singh, U.; Wurtele, E. S.; Schisler, J.; Fenessey, S.; Corvelo, A.; Zody, M. C.; Germer, S.; Salvatore, S.; Levy, S.; Wu, S.; Tatonetti, N.; Shapira, S.; Salvatore, M.; Loda, M.; Westblade, L. F.; Cushing, M.; Rennert, H.; Kriegel, A. J.; Elemento, O.; Imielinski, M.; Borczuk, A. C.; Meydan, C.; Schwar

10.1101/2021.03.08.434433 — microbiology — Posted on 2021-03-09

3535 Defining the scope of the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet): a bottom-up and One Health approach

Mader, R.; EU-JAMRAI, ; Bourely, C.; Amat, J.-P.; Broens, E. M.; Busani, L.; Callens, B.; Crespo-Robledo, P.; Damborg, P.; Filippitzi, M.-E.; Fitzgerald, W.; Grönthal, T.; Haenni, M.; Heuvelink, A.; Hout, J. v.; Kaspar, H.; Munoz Madero, C.; Norström, M.; Pedersen, K.; Pokludova, L.; Dal Pozzo, F.; Slowey, R.; Urdahl, A. M.; Vatopoulos, A.; Zafeiridis, C.; Madec, J.-Y.

10.1101/2021.03.09.434124 — microbiology — Posted on 2021-03-09

3536 Robotic Antimicrobial Susceptibility Platform (RASP): A Next Generation Approach to One-Health Surveillance of Antimicrobial Resistance.

Truswell, A.; Abraham, R.; O'Dea, M.; Lee, Z. Z.; Lee, T.; Laird, T.; Blinco, J.; Kaplan, S.; Turnidge, J.; Trott, D. J.; Jordan, D.; Abraham, S.

10.1101/2021.03.09.434587 — microbiology — Posted on 2021-03-09

3537 Vibrio cholerae's mysterious Seventh Pandemic island (VSP-II) encodes novel Zur-regulated zinc starvation genes involved in chemotaxis and autoaggregation

Murphy, S. G.; Johnson, B. A.; Ledoux, C. M.; Doerr, T.

10.1101/2021.03.09.434465 — microbiology — Posted on 2021-03-09

3538 Fresh extension of Vibrio cholerae competence type IV pili predisposes them for motor-independent retraction

Chlebek, J. L.; Dalia, T. N.; Biais, N.; Dalia, A. B.

10.1101/2021.03.09.434644 — microbiology — Posted on 2021-03-09

3539 The N501Y spike substitution enhances SARS-CoV-2 transmission

Liu, Y.; Liu, J.; Plante, K. S.; Plante, J. A.; Xie, X.; Zhang, X.; Ku, Z.; An, Z.; Scharton, D.; Schindewolf, C.; Menachery, V. D.; Shi, P.-Y.; Weaver, S. C.

10.1101/2021.03.08.434499 — microbiology — Posted on 2021-03-09

3540 Spike mutations in SARS-CoV-2 variants confer resistance to antibody neutralization

Wang, R.; Zhang, Q.; Ge, J.; Ren, W.; Zhang, R.; Lan, J.; Ju, B.; Su, B.; Yu, F.; Chen, P.; Liao, H.; Feng, Y.; Li, X.; Shi, X.; Zhang, Z.; Zhang, F.; Ding, Q.; Zhang, T.; Wang, X.; Zhang, L.

10.1101/2021.03.09.434497 — immunology — Posted on 2021-03-09

3541 REPP: A robust cross-platform solution for online sensorimotor synchronization experiments

Anglada-Tort, M.; Harrison, P. M. C.; Jacoby, N.

10.1101/2021.01.15.426897 — neuroscience — Posted on 2021-03-09

3542 Electrophysiological correlates of mood and reward dynamics in human adolescents

Liuzzi, L.; Chang, K. K.; Keren, H.; Saha, D.; Zheng, C.; Nielson, D. M.; Stringaris, A.

10.1101/2021.03.04.433969 — neuroscience — Posted on 2021-03-09

3543 Mobile brain/body imaging of landmark-based navigation with high-density EEG

Delaux, A.; de Saint Aubert, J.-B.; Ramanoël, S.; Becu, M.; Gerhke, L.; Klug, M.; Chavarriaga, R.; Sahel, J.-A.; Gramann, K.; Arleo, A.

10.1101/2021.01.13.426330 — neuroscience — Posted on 2021-03-09

3544 Characterization of the neurogenic niche in the aging dentate gyrus using iterative immunofluorescence imaging

Cole, J. D.; del Castillo, J. S.; Gut, G.; Gonzalez-Bohorquez, D.; Pelkmans, L.; Jessberger, S.

10.1101/2021.03.03.433747 — neuroscience — Posted on 2021-03-09

3545 Inhalable textile microplastic fibers impair airway epithelial growth

van Dijk, F.; Song, S. S.; van Eck, G.; Wu, X. H.; Bos, S.; Boom, D.; Kooter, I.; Spierings, D. C. J. N.; Wardenaar, R.; Cole, M.; Salvati, A.; Gosens, R.; Melgert, B. N.

10.1101/2021.01.25.428144 — pharmacology and toxicology — Posted on 2021-03-09

3546 Insertions and deletions as phylogenetic signal in alignment-free sequence comparison

Birth, N.; Dencker, T.; Morgenstern, B.

10.1101/2021.02.03.429685 — bioinformatics — Posted on 2021-03-09

3547 FOD-Net: A Deep Learning Method for Fiber Orientation Distribution Angular Super Resolution

Zeng, R.; Lv, J.; Wang, H.; Zhou, L.; Barnett, M.; Calamante, F.; Wang, C.

10.1101/2021.01.17.427042 — bioengineering — Posted on 2021-03-09

3548 Time- and cell-dependent atypia and cell death are caused by progressive deficiency in DNA replication

Lin, A. Y.-S.; Thomas, G. K.; Ang, K.; van Rossum, D. B.; Canfield, V. A.; Cheng, K. C.

10.1101/2020.12.31.425001 — genetics — Posted on 2021-03-09

3549 Differential condensation of sister chromatids coordinates with Cdc6 to ensure distinct cell cycle progression in Drosophila male germline stem cell lineage

Chen, X.; Ranjan, R.; Snedeker, J.; Wooten, M.; Chu, C.; Bracer, S.; Mouton, T.

10.1101/2021.03.08.434490 — developmental biology — Posted on 2021-03-09

3550 Negative correlation between average speed and average turning angle naturally arises for sparsely sampled cell movement data

Ganusov, V. V.; Zenkov, V. S.; Majumder, B.

10.1101/2020.12.30.424897 — immunology — Posted on 2021-03-09

3551 The effect of task demands on the neural patterns generated by novel instruction encoding

Sobrado, A.; Palenciano, A. F.; Gonzalez-Garcia, C.; Ruz, M.

10.1101/2021.03.08.434338 — neuroscience — Posted on 2021-03-09

3552 How Stimulus Statistics Affect The Receptive Fields of V1 Cells

Almasi, A.; Sun, S. H.; Yunzab, M.; Jung, Y. J.; Meffin, H.; Ibbotson, M. R.

10.1101/2021.03.08.434507 — neuroscience — Posted on 2021-03-09

3553 Sodium valproate increases activity of the sirtuin pathway resulting in beneficialeffects for spinocerebellar ataxia-3 in vivo

Watchon, M.; Luu, L.; Robinson, K. J.; Yuan, K. C.; De Luca, A.; Suddull, H. J.; Guillemin, G.; Cole, N. J.; Nicholson, G. A.; Chung, R. S.; Lee, A.; Laird, A. S.

10.1101/2021.03.08.434343 — neuroscience — Posted on 2021-03-09

3554 Two different cell-cycle processes determine the timing of cell division in Escherichia coli

Colin, A.; Micali, G.; Faure, L.; Cosentino Lagomarsino, M.; van Teeffelen, S.

10.1101/2021.03.08.434443 — systems biology — Posted on 2021-03-09

3555 Explainable machine learning models of major crop traits from satellite-monitored continent-wide field trial data

Newman, S. J.; Furbank, R. T.

10.1101/2021.03.08.434495 — plant biology — Posted on 2021-03-09

3556 PulseNet international: the missing link between PFGE and WGS

Adam, I. E.-k. M.

10.1101/2021.03.08.434411 — bioinformatics — Posted on 2021-03-09

3557 Complete genome sequence of Xylella taiwanensis and comparative analysis of virulence gene content with Xylella fastidiosa

Weng, L.-W.; Lin, Y.-C.; Su, C.-C.; Huang, C.-T.; Cho, S.-T.; Chen, A.-P.; Chou, S.-J.; Tsai, C.-W.; Kuo, C.-H.

10.1101/2021.03.08.434500 — genomics — Posted on 2021-03-09

3558 Cost-effective long-read assembly of a hybrid Formica aquilonia x Formica polyctena wood ant genome from a single haploid individual

Nouhaud, P.; Beresford, J.; Kulmuni, J.

10.1101/2021.03.09.434597 — genomics — Posted on 2021-03-09

3559 Using summary statistics to evaluate the genetic architecture of multiplicative combinations of initially analyzed phenotypes with a flexible choice of covariates

Wolf, J. M.; Westra, J.; Tintle, N.

10.1101/2021.03.08.433979 — genetics — Posted on 2021-03-09

3560 Antimalarial mass drug administration in large populations and the evolution of drug resistance

Nguyen, T. D.; Tran, T. N.-A.; Parker, D. M.; White, N. J.; Boni, M. F.

10.1101/2021.03.08.434496 — evolutionary biology — Posted on 2021-03-09

3561 Diversification, Spread, and Admixture of Octoploid Strawberry in the Western Hemisphere

Bird, K. A.; Hardigan, M. A.; Ragsdale, A. P.; Knapp, S. J.; VanBuren, R.; Edger, P. P. A.

10.1101/2021.03.08.434492 — evolutionary biology — Posted on 2021-03-09

3562 Recurrent chromosome reshuffling and the evolution of neo-sex chromosomes in parrots

Huang, Z.; Furo, I.; Peona, V.; Liu, J.; Gomes, A. J. B.; Cen, W.; Huang, H.; Zhang, Y.; Chen, D.; Xue, T.; Chen, Y.; Zhang, Q.; Yue, Z.; Suh, A.; de Oliveira, E. H. C.; Xu, L.

10.1101/2021.03.08.434498 — evolutionary biology — Posted on 2021-03-09

3563 Post-2020 Kunming 30% target can easily protect all endemic sharks and rays in the Western Indian Ocean and more

Cheok, J.; Jabado, R. W.; Ebert, D. A.; Dulvy, N. K.

10.1101/2021.03.08.434293 — ecology — Posted on 2021-03-09

3564 A simple method to separate birds and insects in single-pol weather radar data

Nussbaumer, R.; Schmid, B.; Bauer, S.; Liechti, F.

10.1101/2021.03.08.434434 — ecology — Posted on 2021-03-09

3565 Regulation of oogenesis in the queen honey bee (Apis mellifera)

Aamidor, S. E.; Cardoso Junior, C.; Harianto, J.; Nowell, C. J.; Cole, L.; Oldroyd, B. P.; Ronai, I.

10.1101/2021.03.08.434480 — developmental biology — Posted on 2021-03-09

3566 Ultra-small cells and DPANN genome unveiled inside an extinct vent chimney

Takamiya, H.; Kouduka, M.; Hurutani, H.; Mukai, H.; Yamamoto, T.; Kato, S.; Kodama, Y.; Tomioka, N.; Ito, M.; Suzuki, Y.

10.1101/2021.03.08.430540 — microbiology — Posted on 2021-03-09

3567 Glucose decoration on wall-teichoic acid is required for phage adsorption and InlB-mediated virulence in Listeria ivanovii

Sumrall, E. T.; Schneider, S. R.; Boulos, S.; Loessner, M. J.; Shen, Y.

10.1101/2021.03.08.434512 — microbiology — Posted on 2021-03-09

3568 High Transcriptional Activity and Diverse Functional Repertoires of Hundreds of Giant Viruses in a Coastal Marine System

Ha, A. D.; Moniruzzaman, M.; Aylward, F. O.

10.1101/2021.03.08.434518 — microbiology — Posted on 2021-03-09

3569 Bilateral symmetry of linear streptomycete chromosomes

Algora-Gallardo, L.; Schniete, J. K.; Mark, D. R.; Hunter, I. S.; Herron, P. R.

10.1101/2021.03.09.434596 — microbiology — Posted on 2021-03-09

3570 Self-Healing Neural Codes

Rule, M. E.; O'Leary, T.

10.1101/2021.03.08.433413 — neuroscience — Posted on 2021-03-09

3571 The neural basis of creative production: A cross-modal ALE meta-analysis

Brown, S.; Kim, E.

10.1101/2021.03.09.434575 — neuroscience — Posted on 2021-03-09

3572 Spike-frequency dependent coregulation of multiple ionic conductances in fast-spiking cells forces a metabolic tradeoff

Ban, Y.; Maltby, R. C.; Markham, M. R.

10.1101/2021.03.08.434486 — neuroscience — Posted on 2021-03-09

3573 Snapshot of the Atlantic Forest canopy: surveying arboreal mammals in a biodiversity hotspot

Kaizer, M. C.; Alvim, T. H. G.; Novaes, C. L.; McDevitt, A. D.; Young, R. J.

10.1101/2021.03.08.434374 — zoology — Posted on 2021-03-09

3574 Silkworm spinning: the programmed self-assembly from natural silk fibroin to superfibre

Song, K.; Wang, Y.; Dong, W.; Li, Z.; He, H.; Zhu, P.; Xia, Q.

10.1101/2021.03.08.434386 — zoology — Posted on 2021-03-09

3575 Make Interactive Complex Heatmaps in R

Gu, Z.; Huebschmann, D.

10.1101/2021.03.08.434289 — bioinformatics — Posted on 2021-03-09

3576 HERMES: a molecular formula-oriented method to target the metabolome

Gine, R.; Capellades, J.; Badia, J. M.; Vughs, D.; Schwaiger-Haber, M.; Vinaixa, M.; Brunner, A. M.; Patti, G. J.; Yanes, O.

10.1101/2021.03.08.434466 — bioinformatics — Posted on 2021-03-09

3577 The carbon footprint of bioinformatics

Grealey, J. G.; Lannelongue, L.; Saw, W.; Marten, J.; Meric, G.; Ruiz Carmona, S.; Inouye, M.

10.1101/2021.03.08.434372 — bioinformatics — Posted on 2021-03-09

3578 APPTEST is an innovative new method for the automatic prediction of peptide tertiary structures

Timmons, P. B.; Hewage, C. M.

10.1101/2021.03.09.434600 — bioinformatics — Posted on 2021-03-09

3579 Latent representation of the human pan-celltype epigenome through a deep recurrent neural network

Dsouza, K. B.; Li, A. Y.; Bhargava, V. K.; Libbrecht, M. W.

10.1101/2021.03.08.434446 — bioinformatics — Posted on 2021-03-09

3580 Leveraging omic features with F3UTER enables identification of unannotated 3'UTRs for synaptic genes

Sethi, S.; Zhang, D.; Guelfi, S.; Chen, Z.; Garcia-Ruiz, S.; Ryten, M.; Saini, H.; Botia, J. A.

10.1101/2021.03.08.434412 — bioinformatics — Posted on 2021-03-09

3581 Estimating Ectopic Beat Probability with Simplified Statistical Models that Account for Experimental Uncertainty

Jin, Q.; Greenstein, J. L.; Winlsow, R. L.

10.1101/2021.03.08.434403 — bioengineering — Posted on 2021-03-09

3582 Distributed Brain Co-Processor for Neurophysiologic Tracking and Adaptive Stimulation: Application to Drug Resistant Epilepsy

Sladky, V.; Nejedly, P.; Mivalt, F.; Brinkmann, B. H.; Kim, I.; St. Louis, E. K.; Gregg, N. M.; Lundstrom, B. N.; Crowe, C. M.; Pal Attia, T.; Crepeau, D.; Balzekas, I.; Marks, V.; Wheeler, L. P.; Cimbalnik, J.; Cook, M.; Janca, R.; Sturges, B. K.; Leyde, K.; Miller, K. J.; Van Gompel, J. J.; Denison, T.; Worrell, G. A.; Kremen, V.

10.1101/2021.03.08.434476 — bioengineering — Posted on 2021-03-09

3583 Efficient Representations of Tumor Diversity with Paired DNA-RNA Aberrations

Ke, Q.; Dinalankara, W.; Younes, L.; Geman, D.; Marchionni, L.

10.1101/2020.04.24.060129 — genomics — Posted on 2021-03-09

3584 Identification of putative causal loci in whole-genome sequencing data via knockoff statistics

He, Z.; Liu, L.; Wang, C.; Le Guen, Y.; Lee, J.; Gogarten, S.; Lu, F.; Montgomery, S.; Tang, H.; Silverman, E. K.; Cho, M. H.; Greicius, M.; Ionita-Laza, I.

10.1101/2021.03.08.434451 — genetics — Posted on 2021-03-09

3585 Transposon-induced inversions activate gene expression in Maize pericarp

Sharma, S. P.; Zuo, T.; Peterson, T.

10.1101/2021.03.08.434479 — genetics — Posted on 2021-03-09

3586 Comparative phylogeography of the freshwater mussels of the southeastern United States: reconstructing historic drainages using molecular data

Small, S. T.; Wares, J. P.

10.1101/2021.03.08.434420 — evolutionary biology — Posted on 2021-03-09

3587 A low-cost, long-term underwater camera trap network coupled with deep residual learning image analysis

Bilodeau, S. M.; Schwartz, A. W. H.; Xu, B.; Pauca, V. P.; Silman, M. R.

10.1101/2021.03.08.434472 — ecology — Posted on 2021-03-09

3588 Sexual conflict promotes species coexistence through negative frequency dependence

Gomez-Llano, M.; Nilen, S.; Moodie, I.; Svensson, E.

10.1101/2021.03.08.434376 — ecology — Posted on 2021-03-09

3589 Underwater photo-identification of marine megafauna: an identity card catalogue of sperm whales (Physeter macrocephalus) off Mauritius Island

Sarano, V.; Sarano, F.; Giradet, J.; Preudhomme, A.; Vitry, H.; Heuzey, R.; Sarano, M.; Delfour, F.; Glotin, H.; Adam, O.; Madon, B.; Jung, J.-L.

10.1101/2021.03.08.433909 — ecology — Posted on 2021-03-09

3590 Molecular dietary analyses of western capercaillies (Tetrao urogallus) reveal a diverse diet

Chua, P. Y. S.; Lammers, Y. Y. S.; Menoni, E.; Ekrem, T.; Bohmann, K.; Boessenkool, S.; Alsos, I. G.

10.1101/2021.03.08.434346 — ecology — Posted on 2021-03-09

3591 Ecosystem size and complexity dictate riverine biodiversity

Terui, A.; Kim, S.; Dolph, C. L.; Kadoya, T.; Miyazaki, Y.

10.1101/2021.03.08.434467 — ecology — Posted on 2021-03-09

3592 Stromal inflammation is a targetable driver of hematopoietic aging

Verovskaya, E. V.; Mitchell, C. A.; Calero-Nieto, F. J.; Herault, A.; Dellorusso, P. D.; Wang, X.; Zhang, S. Y.; Flohr Svendsen, A.; Pietras, E. M.; Bakker, S. T.; Ho, T. T.; Gottgens, B.; Passegue, E.

10.1101/2021.03.08.434485 — cell biology — Posted on 2021-03-09

3593 A Tail Fiber Protein and a Receptor-Binding Protein Mediate ICP2 Bacteriophage Interactions with Vibrio cholerae OmpU

Lim, A. N. W.; Yen, M.; Seed, K.; Lazinski, D. W.; Camilli, A.

10.1101/2021.03.08.434494 — microbiology — Posted on 2021-03-09

3594 Legionella pneumophila CRISPR-Cas suggests recurrent encounters with Gokushovirinae

Deecker, S. R.; Urbanus, M. L.; Nicholson, B.; Ensminger, A.

10.1101/2021.03.08.434514 — microbiology — Posted on 2021-03-09

3595 The extracellular milieu of Toxoplasma-s lytic cycle drives lab-adaptation and promotes changes in lipid metabolism primarily driven by transcriptional reprogramming

Primo, V. A.; Rezvani, Y.; Farrell, A.; Vajdi Hoojghan, A.; Marth, G. T.; Zarringhalam, K.; Gubbels, M.-J.

10.1101/2021.03.09.434570 — microbiology — Posted on 2021-03-09

3596 Characterizing neural phase-space trajectories via Principal Louvain Clustering

Dekker, M. M.; Franca, A. S. C.; Panja, D.; Cohen, M. X.

10.1101/2021.03.08.434355 — neuroscience — Posted on 2021-03-09

3597 Infraslow locus coeruleus activity coordinates spindle rhythms and heart rate to gate fluctuating non-REM sleep substates

Osorio-Forero, A.; Cardis, R.; Vantomme, G.; Guillaume-Gentil, A.; Katsioudi, G.; Fernandez, L. M.; Luthi, A.

10.1101/2021.03.08.434399 — neuroscience — Posted on 2021-03-09

3598 Exposure to sevoflurane results in changes of transcription factor occupancy in sperm and inheritance of autism

Wang, H.-L.; Forestier, S.; Corces, V. G.

10.1101/2021.03.08.434461 — neuroscience — Posted on 2021-03-09

3599 Multimodal image fusion via deep generative models

Dimitri, G. M.; Spasov, S.; Duggento, A.; Passamonti, L.; Lio', P.; Toschi, N.

10.1101/2021.03.08.434427 — neuroscience — Posted on 2021-03-09

3600 Variability of EEG electrode positions and their underlying brain regions: visualising gel artifacts from a simultaneous EEG-fMRI dataset

Scrivener, C. L.; Reader, A. T.

10.1101/2021.03.08.434424 — neuroscience — Posted on 2021-03-09

3601 Allopregnanolone mediates affective switching through modulation of oscillatory states in the basolateral amygdala

Antonoudiou, P.; Colmers, P. L.; Walton, N. L.; Weiss, G. L.; Smith, A. C.; Nguyen, D. P.; Lewis, M.; Quirk, M. C.; Melon, L. C.; Maguire, J. L.

10.1101/2021.03.08.434156 — neuroscience — Posted on 2021-03-09

3602 Laminar-specific interhemispheric connectivity mapping with bilateral line-scanning fMRI

Choi, S.; Chen, Y.; Zeng, H.; Biswal, B.; Yu, X.

10.1101/2021.03.08.433876 — neuroscience — Posted on 2021-03-09

3603 Chromogranin A regulates gut permeability via the antagonistic actions of its proteolytic peptides

Muntjewerff, E. M.; Tang, K.; Lutter, L.; Christoffersson, G.; Nicolasen, M. J. T.; Gao, H.; Katkar, G. D.; Das, S.; Beest, M. t.; Ying, W.; Ghosh, P.; El Aidy, S.; Oldenburg, B.; van den Bogaart, G.; Mahata, S. K.

10.1101/2020.09.19.304303 — physiology — Posted on 2021-03-09

3604 A novel nitrogen concentrating mechanism in the coral-algae symbiosome

Thies, A.; Quijada-Rodriguez, A. R.; Zhouyao, H.; Weihrauch, D.; Tresguerres, M.

10.1101/2021.03.08.434475 — physiology — Posted on 2021-03-09

3605 Phage Display Broadly Identifies Inhibitor-reactive Regions in von Willebrand Factor

Yee, A.; Dai, M.; Croteau, S. E.; Shavit, J. A.; Pipe, S. W.; Meng, F.; Ginsburg, D.

10.1101/2021.03.08.434464 — pathology — Posted on 2021-03-09

3606 Palynofacies, environments, and climate changes in the Magdalena River Basin

Lorente, M. A.

10.1101/2021.03.07.434303 — paleontology — Posted on 2021-03-09

3607 High sensitivity dia-PASEF proteomics with DIA-NN and FragPipe

Demichev, V.; Yu, F.; Teo, G. C.; Szyrwiel, L.; Rosenberger, G.; Decker, J.; Kaspar-Schoenefeld, S.; Lilley, K. S.; Muelleder, M.; Nesvizhskii, A. I.; Ralser, M.

10.1101/2021.03.08.434385 — bioinformatics — Posted on 2021-03-09

3608 immuneML: an ecosystem for machine learning analysis of adaptive immune receptor repertoires

10.1101/2021.03.08.433891 — bioinformatics — Posted on 2021-03-09

3609 Chromosomal neighbourhoods allow identification of organ specific changes in gene expression

Das Roy, R.; Hallikas, O.; Christensen, M. M.; Renvoise, E.; Jernvall, J.

10.1101/2020.11.20.390930 — bioinformatics — Posted on 2021-03-09

3610 Gut microbial ecology of Xenopus tadpoles across life stages

Scalvenzi, T.; Clavereau, I.; Bourge, M.; Pollet, N.

10.1101/2020.05.25.110734 — genomics — Posted on 2021-03-09

3611 Climate fluctuations drive the recruitment and growth of temperate grassland plants

Dolezal, J.; Altman, J.; Jandova, V.; Chytry, M.; Conti, L.; Mendez-Castro, F.; Klimesova, J.; Zeleny, D.; Ottaviani, G.

10.1101/2021.03.08.434383 — ecology — Posted on 2021-03-09

3612 Relative effects of edaphic conditions and climate on palm communities in the Central Andes

Montoya, F.; Moraes-R., M.; Fuentes, A. F.; Cayola, L.; Antezana, A.; Miranda, T.; Mosqueira-Meneses, E.; Loza, M. I.; Tello, J. S.

10.1101/2021.03.08.434423 — ecology — Posted on 2021-03-09

3613 ERBB2 is a Key Mediator in Hearing Restoration in Noise-Deafened Young Adult Mice

Zhang, J.; Na, D.; Beaulac, H. J.; Dilts, M.; Henry, K. S.; Bullen, A.; White, P. M.

10.1101/838649 — neuroscience — Posted on 2021-03-09

3614 Wide-Field Calcium Imaging of Dynamic Cortical Networks During Locomotion

West, S. L.; Aronson, J. D.; Popa, L. S.; Carter, R. E.; Feller, K. D.; Chiesl, W. M.; Gerhart, M. L.; Shekhar, A. C.; Ghanbari, L.; Kodandaramaiah, S. B.; Ebner, T. J.

10.1101/2020.07.06.189670 — neuroscience — Posted on 2021-03-09

3615 State anxiety alters the neural oscillatory correlates of predictions and prediction errors during reward learning

Hein, T. P.; Herrojo Ruiz, M.

10.1101/2021.03.08.434415 — neuroscience — Posted on 2021-03-09

3616 CytoPy: an autonomous cytometry analysis framework

Burton, R. J.; Ahmed, R.; Cuff, S.; Baker, S.; Artemiou, A.; Eberl, M.

10.1101/2020.04.08.031898 — bioinformatics — Posted on 2021-03-09

3617 Chimpanzee pant-hoots encode information about individual but not group differences

Desai, N. P.; Fedurek, P.; Slocombe, K. E.; Wilson, M. L.

10.1101/2021.03.09.434515 — animal behavior and cognition — Posted on 2021-03-09

3618 Single cell transcriptomics identifies master regulators of dysfunctional pathways in SOD1 ALS motor neurons

Namboori, S. C.; Thomas, P.; Ames, R.; Hawkins, S.; Garrett, L. O.; Willis, C. R. G.; Rosa, A.; Stanton, L. W.; Bhinge, A.

10.1101/593129 — genomics — Posted on 2021-03-09

3619 Contemporary and historical selection in Tasmanian devils (Sarcophilus harrisii) support novel, polygenic response to transmissible cancer

Stahlke, A. R.; Epstein, B.; Barbosa, S.; Margres, M. J.; Patton, A.; Hendricks, S. A.; Veillet, A.; Fraik, A. K.; Schonfeld, B.; McCallum, H.; Hamede, R.; Jones, M. E.; Storfer, A.; Hohenlohe, P. A.

10.1101/2020.08.07.241885 — evolutionary biology — Posted on 2021-03-09

3620 Optimal Time Lags from Causal Prediction Model Help Stratify and Forecast Nervous System Pathology

Bermperidis, T.; Rai, R.; Torres, E. B.

10.1101/2021.03.05.434171 — neuroscience — Posted on 2021-03-09

3621 Multiphasic value biases in fast-paced decisions

Corbett, E. A.; Martinez-Rodriguez, L. A.; Judd, C.; O'Connell, R. G.; Kelly, S. P.

10.1101/2021.03.08.434248 — neuroscience — Posted on 2021-03-09

3622 Metabolic breakdown of non-small cell lung cancers by mitochondrial HSPD1 targeting

Parma, B.; Ramesh, V.; Gollavilli, P. N.; Siddiqui, A. M.; Pinna, L.; Schwab, A.; Marshall, S.; Zhang, S.; Pilarsky, C.; Napoli, F.; Volante, M.; Urbanczyk, S.; Mielenz, D.; Schroeder, H. D.; Stemmler, M.; Wurdak, H.; Ceppi, P.

10.1101/2021.03.09.434573 — cancer biology — Posted on 2021-03-09

3623 A viral genome packaging ring-ATPase is a flexibly coordinated pentamer

Dai, L.; Singh, D.; Lu, S.; Kottadiel, V.; Vafabakhsh, R.; Mahalingam, M.; Chemla, Y. R.; Ha, T.; Rao, V. B.

10.1101/2021.03.08.434477 — biophysics — Posted on 2021-03-09

3624 Boundary convection during velocity sedimentation in the Optima analytical ultracentrifuge

Berkowitz, S.; Laue, T.

10.1101/2021.03.08.434487 — biophysics — Posted on 2021-03-09

3625 Destruction of DNA-binding proteins by programmable O'PROTAC: Oligonucleotide-based PROTAC

Shao, J.; Yan, Y.; Ding, D.; Wang, D.; He, Y.; Pan, Y.; Yan, W.; Kharbanda, A.; Li, H.-y.; Huang, H.

10.1101/2021.03.08.434493 — biochemistry — Posted on 2021-03-09

3626 A Scalable Screening of E. coli Strains for Recombinant Protein Expression

Morao, L. G.; Manzine, L. R.; Barra, A. L. C.; Clementino, L. O. D.; Gutierrez, R. F.; Wrenger, C.; Polikarpov, I.; Nascimento, A. S.

10.1101/2021.03.09.434560 — molecular biology — Posted on 2021-03-09

3627 Cancer drug discovery as a low rank tensor completion problem

Siruvallur Murali, V.; Agac Cobanoglu, D.; Hsieh, M.; Zinn, M.; Malladi, V. S.; Gesell, J.; Williams, N. S.; Welf, E. S.; Raj, G. V.; Cobanoglu, M. C.

10.1101/2021.03.08.434311 — cancer biology — Posted on 2021-03-09

3628 Sortilin-related receptor is a druggable therapeutic target in breast cancer

Al-Akhrass, H.; Pietilä, M.; Lilja, J.; Vesilahti, E.-M.; Anttila, J. M.; Haikala, H. M.; Munne, P. M.; Klefström, J.; Peuhu, E.; Ivaska, J.

10.1101/2021.03.09.434556 — cancer biology — Posted on 2021-03-09

3629 Entropic pressure controls oligomerization of Vibrio cholerae ParD2 antitoxin

Garcia-Rodriguez, G.; Girardin, Y. A.; Volkov, A. N.; Singh, R. K.; Muruganandam, G.; Van Dyck, J.; Sobott, F.; Versées, W.; Loris, R.

10.1101/2021.03.09.434581 — biophysics — Posted on 2021-03-09

3630 Sub-stoichiometric Hsp104 regulates the genesis and persistence of self-replicable amyloid seeds of a yeast prion protein

Mahapatra, S.; Sarbahi, A.; Madhu, P.; Swasthi, H. M.; Mukhopadhyay, S.

10.1101/2021.03.08.434509 — biophysics — Posted on 2021-03-09

3631 Functional basis of electron transport within photosynthetic complex I

Richardson, K. H.; Wright, J. J.; Simenas, M.; Thiemann, J.; Esteves, A. M.; McGuire, G.; Myers, W. K.; Morton, J. J.; Hippler, M.; Nowaczyk, M. M.; Hanke, G.; Roessler, M. M.

10.1101/2021.03.09.434417 — biophysics — Posted on 2021-03-09

3632 Optimizing mechanostable anchor points of engineered lipocalin in complex with CTLA-4

Liu, Z.; Moreira, R. A.; Dujmovic, A.; Liu, H.; Yang, B.; Poma, A. B.; Nash, M. A.

10.1101/2021.03.09.434559 — biophysics — Posted on 2021-03-09

3633 A common polymorphism that protects from cardiovascular disease increases fibronectin processing and secretion

Soubeyrand, S.; Lau, P.; Nikpay, M.; Dang, A.-T.; McPherson, R.

10.1101/2021.03.09.434522 — biochemistry — Posted on 2021-03-09

3634 Selective and reversible disruption of mitochondrial inner membrane protein complexes by lipophilic cations

Kafkova, A.; Tilokani, L.; Trcka, F.; Sramkova, V.; Vancova, M.; Bily, T.; Nebesarova, J.; Prudent, J.; Trnka, J.

10.1101/2021.03.09.434520 — biochemistry — Posted on 2021-03-09

3635 Endothelial Pannexin 1-TRPV4 channel signaling lowers pulmonary arterial pressure

Daneva, Z.; Ottolini, M.; Chen, Y. L.; Klimentova, E.; Shah, S. A.; Minshall, R. D.; Seye, C. I.; Laubach, V. E.; Isakson, B. E.; Sonkusare, S. K.

10.1101/2021.03.09.434532 — biochemistry — Posted on 2021-03-09

3636 Structural dynamics of cytochrome P450 3A4 in the presence of substrates and cytochrome P450 reductase

Ducharme, J.; Sevrioukova, I. F.; Thibodeaux, C.; Auclair, K.

10.1101/2021.03.09.434557 — biochemistry — Posted on 2021-03-09

3637 ER exit sites in Drosophila display abundant ER-Golgi vesicles and pearled tubes but no megacarriers

Yang, K.; Liu, M.; Feng, Z.; Rojas, M.; Zhou, L.; Ke, H.; Pastor-Pareja, J. C.

10.1101/2021.03.09.434528 — cell biology — Posted on 2021-03-09

3638 VTA MC3R neurons control feeding in an activity and sex-dependent manner in mice

Dunigan, A. I.; Olson, D.; Roseberry, A. G.

10.1101/2021.03.09.434586 — neuroscience — Posted on 2021-03-09

3639 Localization of muscarinic acetylcholine receptor dependent rhythm generating modules in the Drosophila larval locomotor network

Jonaitis, J.; MacLeod, J.; Pulver, S. R.

10.1101/2021.03.08.432150 — neuroscience — Posted on 2021-03-09

3640 Molecular and Structural Basis of Olfactory Sensory Neuron Coalescence by Kirrel Receptors

Wang, J.; Vaddadi, N.; Pak, J. S.; Park, Y.; Quilez, S.; Roman, C. A.; Dumontier, E.; Thornton, J. W.; Cloutier, J.-F.; Özkan, E.

10.1101/2021.03.09.434456 — neuroscience — Posted on 2021-03-09

3641 SARS-CoV-2 evolution in animals suggests mechanisms for rapid variant selection

Bashor, L.; Gagne, R. B.; Bosco-Lauth, A.; Bowen, R.; Stenglein, M.; VandeWoude, S.

10.1101/2021.03.05.434135 — evolutionary biology — Posted on 2021-03-09

3642 The rapid, massive growth of COVID-19 authors in the scientific literature

Ioannidis, J.; Salholz-Hillel, M.; Boyack, K.; Baas, J.

10.1101/2020.12.15.422900 — scientific communication and education — Posted on 2021-03-09

3643 Two-dimensional reward evaluation in mice

Nachev, V.; Rivalan, M.; Winter, Y.

10.1101/2020.04.14.040808 — animal behavior and cognition — Posted on 2021-03-09

3644 Expansion of CD10neg neutrophils and CD14+HLA-DRneg/low monocytes driving proinflammatory responses in patients with acute myocardial infarction

Fraccarollo, D.; Neuser, J.; Moeller, J.; Riehle, C.; Galuppo, P.; Bauersachs, J.

10.1101/2020.09.21.306118 — immunology — Posted on 2021-03-09

3645 Voluntary motor commands are preferentially released during restricted sensorimotor beta rhythm phases

Hussain, S. J.; Vollmer, M. K.; Iturrate, I.; Quentin, R.

10.1101/776393 — neuroscience — Posted on 2021-03-09

3646 Corticothalamic feedback sculpts visual spatial integration in mouse thalamus

Born, G.; Schneider, F. A.; Erisken, S.; Klein, A.; Lao, C. L.; Mobarhan, M. H.; Spacek, M. A.; Einevoll, G. T.; Busse, L.

10.1101/2020.05.19.104000 — neuroscience — Posted on 2021-03-09

3647 Sustained pupil responses are modulated by predictability of auditory sequences

Milne, A. E.; Zhao, S.; Tampakaki, C.; Bury, G.; Chait, M.

10.1101/2020.11.10.376699 — neuroscience — Posted on 2021-03-09

3648 Multiple probabilistic models extract features from protein sequence data and resolve functional diversity of very different protein families

Vicedomini, R.; Bouly, J.-P.; Laine, E.; Falciatore, A.; Carbone, A.

10.1101/717249 — bioinformatics — Posted on 2021-03-09

3649 Heparin promotes fibrillation of most phenol soluble modulin peptides from S. aureus: a possible strengthening of the bacterial biofilm

Najarzadeh, Z.; Zaman, M.; Sereikaite, V.; Strmgaard, K.; Andreasen, M.; Otzen, D. E.

10.1101/2021.03.07.434294 — biophysics — Posted on 2021-03-09

3650 Temporally and Spatially Regulated Collagen XVIII Isoforms Impact Ureteric Patterning Through Their TSP1-like Domain

Rinta-Jaskari, M. M.; Naillat, F.; Ruotsalainen, H. J.; Akram, S. U.; Koivunen, J. T.; Izzi, V.; Ronkainen, V.-P.; Sasaki, T.; Pietilä, I.; Elamaa, H.; Kaur, I.; Manninen, A.; Vainio, S.; Pihlajaniemi, T. A.

10.1101/2021.03.08.434365 — developmental biology — Posted on 2021-03-09

3651 Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes

Devoucoux, M.; Khelifi, G.; Fort, V.; Bourriquen, G.; Hussein, S. M. I.; Cote, J.

10.1101/2021.03.08.434474 — molecular biology — Posted on 2021-03-09

3652 Neuroanatomical organization and functional roles of PVN MC4R pathways in physiological and behavioral regulations

Cui, H.; Singh, U.; Saito, K.; Toth, B. A.; Dickey, J. E.; Rodeghiero, S. R.; Deng, Y.; Deng, g.; Xue, B.; Zhu, Z.; Jiang, J.; Zingman, L. V.

10.1101/2021.03.08.431341 — neuroscience — Posted on 2021-03-09

3653 The effect of vascular health factors on white matter microstructure mediates age-related differences in executive function performance

Hoagey, D. A.; Lazarus, L. T. T.; Rodrigue, K. M.; Kennedy, K. M.

10.1101/2020.05.14.096677 — neuroscience — Posted on 2021-03-09

3654 Maternal cradling bias drives early handedness in infant monkeys: A longitudinal study of grasping lateralization in baboons

Boulinguez-Ambroise, G.; Pouydebat, E.; Disarbois, E.; Meguerditchian, A.

10.1101/2021.03.09.434410 — animal behavior and cognition — Posted on 2021-03-09

3655 Mitochondrial variant enrichment from high-throughput single-cell RNA-seq resolves clonal populations

Miller, T. E.; Lareau, C. A.; Verga, J. A.; Ssozi, D.; Ludwig, L. S.; El Farran, C.; Griffin, G. K.; Lane, A. A.; Bernstein, B. E.; Sankaran, V. G.; van Galen, P.

10.1101/2021.03.08.434450 — genomics — Posted on 2021-03-09

3656 Genome-wide annotation of gene regulatory elements linked to cell fitness

Klann, T.; Barrera, A.; Ettyreddy, A.; Rickels, R.; Bryois, J.; Jiang, S.; Adkar, S.; Iglesias, N.; Sullivan, P.; Reddy, T. E.; Crawford, G. E.; Gersbach, C.

10.1101/2021.03.08.434470 — genomics — Posted on 2021-03-09

3657 RBPMS2 is a conserved regulator of alternative splicing that promotes myofibrillar organization and optimal calcium handling in cardiomyocytes

Akerberg, A. A.; Trembley, M.; Butty, V.; Schwertner, A.; Zhou, L.; Beerens, M.; Liu, X.; Mahamdeh, M.; Yuan, S.; MacRae, C.; Nguyen, C.; Pu, W. T.; Burns, C. E.; Burns, C. G.

10.1101/2021.03.08.434502 — developmental biology — Posted on 2021-03-09

3658 BIN1 genetic risk factor for Alzheimer is sufficient to induce early structural tract alterations in entorhinal cortex-dentate gyrus pathway and related hippocampal multi-scale impairments

Daudin, R.; Marechal, D.; Golgolab, R.; Wang, Q.; Abe, Y.; Tsurugizawa, T.; Bourg, N.; Sartori, M.; Loe-Mie, Y.; Lipecka, J.; Guerrera, C.; McKenzie, A.; Potier, B.; Dutar, P.; Viard, J.; Lepagnol-Bestel, A.-M.; Winkeler, A.; Uszynski, I.; Hindie, V.; Birling, M.-C.; Lindner, L.; Chevalier, C.; Pavlovic, G.; Reiss, M.; Kranz, H.; Dupuis, G.; Leveque-Fort, S.; Diaz, J.; Davenas, E.; Dembele, D.; Atas-Ozcan, H.; Laporte, J.; Thibault-Carpentier, C.; Malissen, B.; Rain, J.-C.; Poupon, C.; Le Bihan, D.; Zhang, B.; Herault, Y.; Ciobanu, L.; Simonneau, M.

10.1101/437228 — neuroscience — Posted on 2021-03-09

3659 Atrx deletion impairs cGAS-STING signaling and increases response to radiation and oncolytic herpesvirus in sarcoma

Floyd, W.; Pierpoint, M.; Su, C.; Luo, L.; Deland, K.; Wisdom, A. J.; Zhu, D.; Ma, Y.; DeWitt, S. B.; Williams, N. T.; Somarelli, J. A.; Corcoran, D. L.; Eward, W. C.; Cardona, D. M.; Kirsch, D. G.

10.1101/2021.03.08.434225 — cancer biology — Posted on 2021-03-09

3660 Parasitic success and venom composition evolve upon specialization of parasitoid wasps to different host species

Cavigliasso, F.; Mathe-Hubert, H.; Gatti, J.-L.; Colinet, D.; Poirie, M.

10.1101/2020.10.24.353417 — evolutionary biology — Posted on 2021-03-09

3661 Prevalence, complete genome and metabolic potentials of a phylogenetically novel cyanobacterial symbiont in the coral-killing sponge, Terpios hoshinota

Chen, Y.-H.; Chen, H.-J.; Yang, C.-Y.; Shiu, J.-H.; Hoh, D. Z.; Chiang, P.-W.; Chow, W. S.; Chen, C. A.; Shih, T.-H.; Lin, S.-H.; Yang, C.-M.; Reimer, J. D.; Hirose, E.; Iskandar, B. H.; Huang, H.; Schupp, P. J.; Tan, C. H. J.; Yamashiro, H.; Liao, M.-H.; Tang, S.-L.

10.1101/2021.02.04.429686 — ecology — Posted on 2021-03-09

3662 Knockout of zebrafish desmin genes does not cause skeletal muscle degeneration but alters calcium flux

Kayman Kurekci, G.; Kural Mangit, E.; Koyunlar, C.; Unsal, S.; Saglam, B.; Ergin, B.; Gizer, M.; Uyanik, I.; Boustanabadimaralan Duz, N.; Korkusuz, P.; Talim, B.; Purali, N.; Hughes, S. M.; Dincer, P. R.

10.1101/2020.10.16.342485 — developmental biology — Posted on 2021-03-09

3663 Cross-modal perceptual enhancement of unisensory targets is uni-directional and does not affect temporal expectations

Ball, F.; Nentwich, A.; Noesselt, T.

10.1101/2021.03.06.434204 — neuroscience — Posted on 2021-03-09

3664 Context dependency of time-based event-related expectations for different modalities

Ball, F.; Andreca, J.; Noesselt, T.

10.1101/2021.03.06.434208 — neuroscience — Posted on 2021-03-09

3665 Apomixis and genetic background affect distinct traits in Hieracium pilosella L. grown under competition

Sailer, C.; Tiberi, S.; Schmid, B.; Stoecklin, J.; Grossniklaus, U.

10.1101/2020.12.30.424832 — plant biology — Posted on 2021-03-09

3666 Unsupervised tensor decomposition-based method to extract candidate transcription factors as histone modification bookmarks in post-mitotic transcriptional reactivation

Taguchi, Y.-h.; Turki, T.

10.1101/2020.09.23.309633 — bioinformatics — Posted on 2021-03-09

3667 Synergism between potassium and nitrate enhances the alleviation of ammonium toxicity in rice seedling root

Fang, G.; Yang, J.; Sun, T.; Wang, X.; Li, Y.

10.1101/2021.03.08.434377 — plant biology — Posted on 2021-03-08

3668 Short duration overnight cattle kraaling in natural rangelands: does time after kraal use affect their utilization by wildlife and above ground grass parameters?

Huruba, R.; Nemera, S.; Ngute, F.; Sahomba, M.; Mundy, P. J.; Sebata, A.; MacFadyen, D. N.

10.1101/2021.03.08.434375 — ecology — Posted on 2021-03-08

3669 Bioacoustics for in situ validation of species distribution modelling: An example with bats in Brazil

Hintze, F.; Machado, R. B.; Bernard, E.

10.1101/2021.03.08.434378 — ecology — Posted on 2021-03-08

3670 Homeostatic depression shows heightened sensitivity to synaptic calcium

Yeates, C. J.; Frank, C. A.

10.1101/2020.10.12.336883 — neuroscience — Posted on 2021-03-08

3671 Aerodynamics and motor control of ultrasonic vocalizations for social communication in mice and rats

Haakansson, J.; Jiang, W.; Xue, Q.; Zheng, X.; Ding, M.; Agarwal, A. A.; Elemans, C. P.

10.1101/2021.03.08.434401 — neuroscience — Posted on 2021-03-08

3672 Automatic Landmark Detection of Human Back Surface from Depth Images via Deep Learning

Delgarmi, M.; Heravi, H.; Rahimpour Jounghani, A.; Shahrezie, A.; Ebrahimi, A.; Shamsi, M.

10.1101/2021.02.04.429842 — bioengineering — Posted on 2021-03-08

3673 Depth Dataset Using Microsoft Kinect-v2

Heravi, H.; Delgarmi, M.; Rahimpour Jounghani, A.; shahrezaie, A.; Ebrahimi, A.; Shamsi, M.

10.1101/2021.02.04.429850 — bioengineering — Posted on 2021-03-08

3674 Etmopterus lantern sharks use coelenterazine as the substrate for their luciferin-luciferase bioluminescence system

Mizuno, G.; Yano, D.; Paitio, J.; Endo, H.; Oba, Y.

10.1101/2021.03.01.433353 — biochemistry — Posted on 2021-03-08

3675 TAK1 blockade as a therapy for retinal neovascularization

Lin, F.-L.; Wang, J.-H.; Chen, J.; Zhu, L.; Chuang, Y.-F.; Tu, L.; Ma, C.; Lama, S.; Ling, D.; Wong, R. C.-B.; Hewitt, A. W.; Tseng, C.-L.; Bui, B. V.; van Wijngaarden, P.; Dusting, G. J.; Wang, P.-Y.; Liu, G.-S.

10.1101/2021.01.29.428701 — biochemistry — Posted on 2021-03-08

3676 Quantitative Theory for the Diffusive Dynamics of Liquid Condensates

Hubatsch, L.; Jawerth, L. M.; Love, C.; Bauermann, J.; Tang, T.-Y. D.; Bo, S.; Hyman, A. A.; Weber, C. A.

10.1101/2021.03.08.434288 — biophysics — Posted on 2021-03-08

3677 The force loading rate drives cell mechanosensing through both reinforcement and fluidization

Andreu, I.; Falcones, B.; Hurst, S.; Chahare, N.; Quiroga, X.; Le Roux, A.-L.; Kechagia, Z.; Beedle, A. E. M.; Elosegui-Artola, A.; Trepat, X.; Farre, R.; Betz, T.; Almendros, I.; Roca-Cusachs, P.

10.1101/2021.03.08.434428 — biophysics — Posted on 2021-03-08

3678 swCAM: estimation of subtype-specific expressions in individual samples with unsupervised sample-wise deconvolution

Chen, L.; Wu, C.-T.; Lin, C.-H.; Dai, R.; Liu, C.; Clarke, R.; Yu, G.; Van Eyk, J. E.; Herrington, D. M.; Wang, Y.

10.1101/2021.01.04.425315 — bioinformatics — Posted on 2021-03-08

3679 Placenta DNA methylation at ZNF300 is associated with fetal sex and placental morphology

Ladd-Acosta, C.; Andrews, S. V.; Bakulski, K. M.; Feinberg, J. I.; Tryggvadottir, R.; Yao, R.; Croen, L. A.; Hertz-Picciotto, I.; Newschaffer, C. J.; Salafia, C. M.; Feinberg, A. P.; Hansen, K. D.; Fallin, M. D.

10.1101/2021.03.05.433992 — genomics — Posted on 2021-03-08

3680 Large-scale placenta DNA methylation mega-analysis reveals fetal sex-specific differentially methylated CpG sites and regions

Andrews, S. V.; Yang, I. J.; Froehlich, K.; Oskotsky, T.; Sirota, M.

10.1101/2021.03.04.433985 — genomics — Posted on 2021-03-08

3681 Chelator sensing and lipopeptide interplay mediates molecular interspecies interactions between soil bacilli and pseudomonads

Andric, S.; Meyer, T.; Rigolet, A.; Arguelles Arias, A.; Steels, S.; Hoff, G.; Hofte, M.; De Mot, R.; McCann, A.; De Pauw, E.; Ongena, M.

10.1101/2021.02.22.432387 — microbiology — Posted on 2021-03-08

3682 Patterns of gene content and co-occurrence constrain the evolutionary path toward animal association in CPR bacteria

Jaffe, A. L.; He, C.; Keren, R.; Valentin-Alvarado, L. E.; Munk, P. L.; Bouma-Gregson, K.; Farag, I. F.; Amano, Y.; Sachdeva, R.; West, P. T.; Banfield, J. F.

10.1101/2021.03.03.433784 — microbiology — Posted on 2021-03-08

3683 A VLP-based vaccine targeting ANGPTL3 lowers plasma triglycerides in mice

Fowler, A.; Sampson, M.; Remaley, A. T.; Chackerian, B.

10.1101/2021.03.08.434130 — immunology — Posted on 2021-03-08

3684 Perceptual difficulty modulates the direction of information flow in familiar face recognition

Karimi-Rouzbahani, H.; Ramezani, F.; Woolgar, A.; Rich, A. N.; Ghodrati, M.

10.1101/2020.08.10.245241 — neuroscience — Posted on 2021-03-08

3685 IsoSolve: an integrative framework to improve isotopic coverage and consolidate isotopic measurements by MS and/or NMR

Millard, P.; Sokol, S.; Kohlstedt, M.; Wittmann, C.; Letisse, F.; Lippens, G.; Portais, J.-C.

10.1101/2021.03.08.430771 — systems biology — Posted on 2021-03-08

3686 Genomic environments scale the activities of diverse core promoters

Hong, C. K.; Cohen, B. A.

10.1101/2021.03.08.434469 — systems biology — Posted on 2021-03-08

3687 Nurturing Diversity and Inclusion in AI in Biomedicine through a Virtual Summer Program for High School Students

Oskotsky, T.; Bajaj, R.; Burchard, J.; Cavazos, T. B.; Chen, I.; Connell, W.; Eaneff, S.; Grant, T.; Kanungo, I.; Lindquist, K.; Myers-Turnbull, D. J.; Naing, Z. Z. C.; Tang, A.; Vora, B.; Wang, J. X.; Karim, I.; Swadling, C.; Yang, J.; AI4ALL Student Cohort 2020, ; Sirota, M.

10.1101/2021.03.06.434213 — scientific communication and education — Posted on 2021-03-08

3688 A H3K9me2-Binding Protein AGDP3 Limits DNA Methylation and Transcriptional Gene Silencing in Arabidopsis

Zhou, X.; Wei, M.; Nie, W.; Xi, Y.; Du, X.; Tang, K.; Peng, L.; Zheng, Q.; Satheesh, V.; Luo, J.; Wang, Y.; Liu, R.; Yang, Z.; Zhong, Y.; An, G.-Y.; Zhu, J.-K.; Du, J.; Lei, M.

10.1101/2021.03.08.434320 — plant biology — Posted on 2021-03-08

3689 Transplanting increases the leaf production rate in rice, consequently modifying plant development and growth

Clerget, B.; Pasuquin, E.; Carandang, R.; Domingo, A. J.; Layaoen, H. L.; Bueno, C.

10.1101/2021.03.08.434354 — plant biology — Posted on 2021-03-08

3690 Latent effects of winter warming on Olympia oyster reproduction and larval viability

Spencer, L. H.; Horkan, E.; Crim, R.; Roberts, S.

10.1101/2020.06.01.127977 — physiology — Posted on 2021-03-08

3691 Transfer learning between preclinical models and human tumors identifies conserved NK cell activation signature in anti-CTLA-4 responsive tumors

Davis-Marcisak, E. F.; Fitzgerald, A. A.; Kessler, M. D.; Danilova, L.; Jaffee, E. M.; Zaidi, N.; Weiner, L. M.; Fertig, E. J.

10.1101/2020.05.31.125625 — cancer biology — Posted on 2021-03-08

3692 Sequence dependence of biomolecular phase separation

Weiner, B. G.; Meir, Y.; Wingreen, N. S.

10.1101/2020.09.24.312330 — biophysics — Posted on 2021-03-08

3693 cinaR: A comprehensive R package for the differential analyses and functional interpretation of ATAC-seq data

Ucar, D.; Karakaslar, E. O.

10.1101/2021.03.05.434143 — bioinformatics — Posted on 2021-03-08

3694 Conditional prediction of consecutive tumor evolution using cancer progression models: What genotype comes next?

Diaz-Colunga, J.; Diaz-Uriarte, R.

10.1101/2020.12.16.423099 — bioinformatics — Posted on 2021-03-08

3695 Segmentation of Tissues and Proliferating Cells in Light-Sheet Microscopy Images using Convolutional Neural Networks

Lo Vercio, L. D.; Green, R. M.; Robertson, S.; Guo, S. H.; Dauter, A.; Marchini, M.; Vidal-Garcia, M.; Zhao, X.; Marcucio, R.; Hallgrimsson, B.; Forkert, N. D.

10.1101/2021.03.08.434453 — bioinformatics — Posted on 2021-03-08

3696 Genome-wide characterization of human minisatellite VNTRs: population-specific alleles and gene expression differences

Eslami Rasekh, M.; Hernandez, Y.; Drinan, S. D.; Fuxman Bass, J. I.; Benson, G.

10.1101/2020.11.03.367367 — bioinformatics — Posted on 2021-03-08

3697 Optimal transport analysis reveals trajectories in steady-state systems

Zhang, S.; Afanassiev, A.; Greenstreet, L.; Matsumoto, T.; Schiebinger, G.

10.1101/2021.03.02.433630 — bioinformatics — Posted on 2021-03-08

3698 Unbiased population heterozygosity estimates from genome-wide sequence data

Schmidt, T. L.; Jasper, M.; Weeks, A. R.; Hoffmann, A. A.

10.1101/2020.12.20.423694 — genomics — Posted on 2021-03-08

3699 Resource uptake and the evolution of moderately efficient enzymes

Labourel, F.; Rajon, E.

10.1101/2020.11.08.373290 — evolutionary biology — Posted on 2021-03-08

3700 A General Birth-Death-Sampling Model for Epidemiology and Macroevolution

MacPherson, A.; Louca, S.; McLaughlin, A.; Joy, J. B.; Pennell, M. W.

10.1101/2020.10.10.334383 — evolutionary biology — Posted on 2021-03-08

3701 Comprehensive analysis of Japanese archipelago population history by detecting ancestry-marker polymorphisms without using ancient DNA data

Watanabe, Y.; Ohashi, J.

10.1101/2020.12.07.414037 — evolutionary biology — Posted on 2021-03-08

3702 The Phage-shock-protein (PSP) Envelope Stress Response: Discovery of Novel Partners and Evolutionary History

Ravi, J.; Anantharaman, V.; Chen, S. Z.; Datta, P.; Aravind, L.; Gennaro, M. L.

10.1101/2020.09.24.301986 — evolutionary biology — Posted on 2021-03-08

3703 Regulation by the pitcher plant Sarracenia purpurea of the structure of its inquiline food web

Ellison, A. M.; Gotelli, N. J.; Błedzki, L. A.; Butler, J. L.

10.1101/2020.05.15.098004 — ecology — Posted on 2021-03-08

3704 Zooplankton trophic dynamics drive carbon export efficiency

Serra-Pompei, C.; Ward, B. A.; Pinti, J.; Visser, A. W.; Kiorboe, T.; Andersen, K. H.

10.1101/2021.03.08.434455 — ecology — Posted on 2021-03-08

3705 High content Image Analysis to study phenotypic heterogeneity in endothelial cell monolayers

Chesnais, F. L.; Le Caillec, J.; Roy, E.; Danovi, D.; Veschini, L.

10.1101/2020.11.17.362277 — cell biology — Posted on 2021-03-08

3706 Newly developed ad hoc molecular assays show how eDNA can witness and anticipate the monk seal recolonization of central Mediterranean

Valsecchi, E.; Coppola, E.; Pires, R.; Parmegiani, A.; Casiraghi, M.; Galli, P.; Bruno, A.

10.1101/2021.02.13.431078 — molecular biology — Posted on 2021-03-08

3707 Novel Chlamydiae and Amoebophilus endosymbionts are prevalent in wild isolates of the model social amoebae Dictyostelium discoideum

Haselkorn, T. S.; Jimenez, D.; Bashir, U.; Sallinger, E.; Queller, D. C.; Strassmann, J. E.; DiSalvo, S.

10.1101/2020.09.30.320895 — microbiology — Posted on 2021-03-08

3708 Integrative multi-omics profiling reveals cAMP-independent mechanisms regulating hyphal morphogenesis in Candida albicans

Min, K.; Jannace, T. F.; Si, H.; Veeramah, K. R.; Haley, J. D.; Konopka, J. B.

10.1101/2021.03.08.433668 — microbiology — Posted on 2021-03-08

3709 The anti-sigma factor MucA is required for viability in Pseudomonas aeruginosa

Schofield, M. C.; Rodriguez, D.; Kidman, A. A.; Cassin, E. K.; Michaels, L. A.; Campbell, E. A.; Jorth, P. A.; Tseng, B. S.

10.1101/2020.08.17.253617 — microbiology — Posted on 2021-03-08

3710 Activation of a signaling pathway by the physical translocation of a chromosome

Guzzo, M.; Sanderlin, A. G.; Castro, L. K.; Laub, M. T.

10.1101/2021.03.08.434431 — microbiology — Posted on 2021-03-08

3711 In vitro and in vivo interaction of caspofungin with isavuconazole against Candida auris planktonic cells and biofilms

Nagy, F.; Toth, Z.; Nyikos, F.; Forgacs, L.; Jakab, A.; Borman, A. M.; Majoros, L.; Kovacs, R.

10.1101/2021.03.08.434267 — microbiology — Posted on 2021-03-08

3712 Multiple classes of bactericidal antibiotics cause DNA double strand breaks in Staphylococcus aureus

Clarke, R. S.; Ha, K. P.; Edwards, A. M.

10.1101/2021.03.05.434095 — microbiology — Posted on 2021-03-08

3713 Population genomics reveals molecular determinants of specialization to tomato in the polyphagous fungal pathogen Botrytis cinerea

Mercier, A.; Simon, A.; Lapalu, N.; GIRAUD, T.; Bardin, M.; Walker, A.-S.; Viaud, M.; Gladieux, P.

10.1101/2020.07.24.219691 — microbiology — Posted on 2021-03-08

3714 Strategic trade-offs between choice biases and accuracy for decisions based on asymmetric, rare evidence

Eissa, T. L.; Gold, J. I.; Josic, K.; Kilpatrick, Z. P.

10.1101/2020.12.06.413591 — neuroscience — Posted on 2021-03-08

3715 Stimulus-specific plasticity in human visual gamma-band activity and functional connectivity

Stauch, B. J.; Peter, A.; Schuler, H.; Fries, P.

10.1101/2020.11.13.381467 — neuroscience — Posted on 2021-03-08

3716 BIN1 genetic risk factor for Alzheimer is sufficient to induce early structural tract alterations in entorhinal cortex-dentate gyrus pathway and related hippocampal multi-scale impairments

Daudin, R.; Marechal, D.; Wang, Q.; Abe, Y.; Tsurugizawa, T.; Bourg, N.; Sartori, M.; Loe-Mie, Y.; Lipecka, J.; Guerrera, C.; McKenzie, A.; Potier, B.; Dutar, P.; Viard, J.; Lepagnol-Bestel, A.-M.; Winkeler, A.; Uszynski, I.; Hindie, V.; Birling, M.-C.; Lindner, L.; Chevalier, C.; Pavlovic, G.; Reiss, M.; Kranz, H.; Dupuis, G.; Leveque-Fort, S.; Diaz, J.; Davenas, E.; Dembele, D.; Atas-Ozcan, H.; Laporte, J.; Thibault-Carpentier, C.; Malissen, B.; Rain, J.-C.; Poupon, C.; Le Bihan, D.; Zhang, B.; Herault, Y.; Ciobanu, L.; Simonneau, M.

10.1101/437228 — neuroscience — Posted on 2021-03-08

3717 An open source platform for presenting dynamic visual stimuli

Swanson, K.; White, S. R.; Preston, M. W.; Wilson, J.; Mitchell, M.; Laubach, M.

10.1101/2020.12.24.424344 — neuroscience — Posted on 2021-03-08

3718 Virtual connectomic datasets in Alzheimer's Disease and aging using whole-brain network dynamics modelling

Arbabyazd, D. M.; Shen, K.; Wang, Z.; Hofmann-Apitius, M.; Ritter, P.; McIntosh, A. R.; Battaglia, D.; Jirsa, V.

10.1101/2020.01.18.911248 — neuroscience — Posted on 2021-03-08

3719 Executive function supports single-shot endowment of value to arbitrary transient goals

McDougle, S. D.; Ballard, I. C.; Baribault, B.; Bishop, S. J.; Collins, A. G. E.

10.1101/2020.10.21.348938 — neuroscience — Posted on 2021-03-08

3720 Arc rescues defective synaptic plasticity and cognitive dysfunction in sepsis-associated encephalopathy

Grünewald, B.; Wickel, J.; Hahn, N.; Hörhold, F.; Rupp, H.; Chung, H.-Y.; Haselmann, H.; Strauss, A. S.; Schmidl, L.; Hempel, N.; Grünewald, L.; Urbach, A.; Blaess, M.; Claus, R. A.; König, R.; Geis, C.

10.1101/2021.03.04.433352 — neuroscience — Posted on 2021-03-08

3721 ANCHOR, a technical approach to monitor single-copy locus localization in planta

Meschichi, A.; Ingouff, M.; Picart, C.; Mirouze, M.; Desset, S.; Gallardo, F.; Bystricky, K.; Picault, N.; Rosa, S.; Pontvianne, F.

10.1101/2021.03.08.434382 — plant biology — Posted on 2021-03-08

3722 Allicin From Garlic Disrupts the Cytoskeleton in Plants

Noll, U.; Schreiber, M.; Hermanns, M.; Mertes, C. A.; Slusarenko, A. J.; Gruhlke, M. C. H.

10.1101/2021.03.08.434082 — plant biology — Posted on 2021-03-08

3723 Integrin α5β1 nano-presentation regulates collective keratinocyte migration independent of substrate rigidity

Di Russo, J.; Young, J. L.; Wegner, J. W. R.; Steins, T.; Kessler, H.; Spatz, J. P.

10.1101/2021.03.08.434437 — biophysics — Posted on 2021-03-08

3724 AI-driven prediction of SARS-CoV-2 variant binding trends from atomistic simulations

Capponi, S.; Wang, S.; Bianco, S.

10.1101/2021.03.07.434295 — biophysics — Posted on 2021-03-08

3725 Mixed fatty acid-phospholipid protocell networks

Poldsalu, I.; Koksal, E. S.; Gozen, I.

10.1101/2021.03.08.434432 — biophysics — Posted on 2021-03-08

3726 The neuronal calcium sensor Synaptotagmin-1 and SNARE proteins cooperate to dilate fusion pores

Wu, Z.; Dharan, N.; McDargh, Z. A.; Thiyagarajan, S.; O'Shaughnessy, B.; Karatekin, E.

10.1101/623827 — biophysics — Posted on 2021-03-08

3727 Genome-Wide Covariation in SARS-CoV-2

Cresswell-Clay, E. C.; Periwal, V.

10.1101/2021.03.08.434363 — genomics — Posted on 2021-03-08

3728 Transgenic mice for in vivo epigenome editing with CRISPR-based systems

Gemberling, M.; Siklenka, K.; Rodriguez, E.; Eisinger, K.; Barrera, A.; Liu, F.; Kantor, A.; Li, L.; Cigliola, V.; Hazlett, M.; Williams, C.; Bartelt, L.; Bodle, J.; Daniels, H.; Rouse, C.; Hilton, I.; Madigan, V.; Asokan, A.; Ciofani, M.; Poss, K.; Reddy, T. E.; West, A.; Gersbach, C.

10.1101/2021.03.08.434430 — genomics — Posted on 2021-03-08

3729 A cross-cohort analysis of autosomal DNA methylation sex differences in the term placenta

Inkster, A. M.; Yuan, V.; Konwar, C.; Matthews, A. M.; Brown, C. J.; Robinson, W. P.

10.1101/2021.03.08.434471 — genomics — Posted on 2021-03-08

3730 Rapid Identification of Methylase Specificity (RIMS-seq) jointly identifies methylated motifs and generates shotgun sequencing of bacterial genomes

Baum, C.; Lin, Y.-C.; Fomenkov, A.; Anton, B. P.; Chen, L.; Evans, T. C.; Roberts, R. J.; Tolonen, A. C.; Ettwiller, L.

10.1101/2021.03.08.434449 — genomics — Posted on 2021-03-08

3731 Trio-binned genomes of the woodrats Neotoma bryanti and N. lepida reveal novel gene islands and rapid copy number evolution of xenobiotic metabolizing cytochrome p450 genes

Greenhalgh, R.; Holding, M. L.; Orr, T. J.; Henderson, J. B.; Parchman, T. L.; Matocq, M. D.; Shapiro, M. D.; Dearing, M. D.

10.1101/2021.03.08.434435 — genomics — Posted on 2021-03-08

3732 Genome Size Estimation and Full-length Transcriptome of Sphingonotus tsinlingensis: Genetic Background for the Drought-Adapted Grasshopper

Zhao, L.; Wang, H.; Wu, L.; Sun, K.; Guan, D.-L.; Xu, S.-Q.

10.1101/2021.03.08.434347 — genetics — Posted on 2021-03-08

3733 Vinculin controls endothelial cell junction dynamics during vascular lumen formation

Kotini, M. P.; van der Stoel, M. M.; Han, M. K.; Kirchmaier, B.; de Rooij, J.; Affolter, M.; Huveneers, S.; Belting, H.-G.

10.1101/2021.03.08.434441 — cell biology — Posted on 2021-03-08

3734 Identification of novel bat coronaviruses sheds light on the evolutionary origins of SARS-CoV-2 and related viruses

Zhou, H.; Ji, J.; Chen, X.; Bi, Y.; Li, J.; Hu, T.; Song, H.; Chen, Y.; Cui, M.; Zhang, Y.; Hughes, A. C.; Holmes, E. C.; Shi, W.

10.1101/2021.03.08.434390 — microbiology — Posted on 2021-03-08

3735 Apparent growth paradox of Staphylococcus epidermidis in response to extremely low frequency electromagnetic radiation exposure

Malik, D.; Pineda, E.; Mejia Zambrana, D.

10.1101/2021.03.06.434218 — microbiology — Posted on 2021-03-08

3736 DNA methylation patterns in bacteria of the genus Ensifer during free living growth and during nitrogen-fixing symbiosis with Medicago spp.

diCenzo, G. C.; Cangioli, L.; Nicoud, Q.; Cheng, J. H. T.; Blow, M. J.; Shapiro, N.; Woyke, T.; Alunni, B.; Mengoni, A.; Mergaert, P.

10.1101/2021.03.08.434416 — microbiology — Posted on 2021-03-08

3737 Antimicrobials from a feline commensal bacterium inhibit skin infection by drug-resistant S. pseudintermedius.

O'Neill, A. M.; Worthing, K. A.; Kulkarni, N.; Li, F.; Nakatsuji, T.; Mills, R. H.; Cheng, J. Y.; Gonzalez, D. J.; Norris, J. M.; Gallo, R. L.

10.1101/2021.03.08.432323 — microbiology — Posted on 2021-03-08

3738 Full-length native CGRP neuropeptide and its stable analogue SAX, but not CGRP peptide fragments, inhibit mucosal HIV-1 transmission

Bomsel, M.; Sams, A.; Cohen, E.; Sennepin, A.; Siracusano, G.; Sanvito, F.; Edvinsson, L.; Lopalco, L.; Ganor, Y.

10.1101/2021.03.08.434421 — microbiology — Posted on 2021-03-08

3739 Glucose decoration on wall-teichoic acid is required for phage adsorption and InlB-mediated virulence in Listeria ivanovii

Sumrall, E. T.; Schneider, S. R.; Boulos, S.; Loessner, M. J.; Shen, Y.

10.1101/2021.03.08.434348 — microbiology — Posted on 2021-03-08

3740 Capsaicin activates TRPV1 in human Langerhans cells and inhibits mucosal HIV-1 transmission via secreted CGRP

Cohen, E.; Zhu, A.; Auffray, C.; Bomsel, M.; Ganor, Y.

10.1101/2021.03.08.434408 — microbiology — Posted on 2021-03-08

3741 G-quadruplex RNA motifs influence gene expression in the malaria parasite Plasmodium falciparum

Dumetz, F.; Chow, E. Y.-C.; Harris, L. M.; Umar, M. I.; Jensen, A.; Chung, B.; Chan, T. F.; Merrick, C. J.; Kwok, C. K.

10.1101/2021.03.08.434398 — microbiology — Posted on 2021-03-08

3742 Hillslope geodiversity shapes ammonia-oxidizing communities and other microbial regulators in a semi-arid shrubland

Szitenberg, A.; Alexander-Shani, R.; Yizhak, H.; Stavi, I.

10.1101/2021.03.08.434393 — microbiology — Posted on 2021-03-08

3743 Differential effects on neuromuscular physiology between Sod loss-of-function mutation and paraquat-induced oxidative stress in Drosophila

Ueda, A.; Iyengar, A.; Wu, C.-F.

10.1101/2021.03.08.434419 — neuroscience — Posted on 2021-03-08

3744 Structural Analysis of Spike Protein Mutations in an Emergent SARS-CoV-2 Variant from the Philippines

Bascos, N. A. D.; Mirano-Bascos, D.; Saloma, C. P.

10.1101/2021.03.06.434059 — biophysics — Posted on 2021-03-08

3745 Comparative studies of the seven human coronavirus envelope proteins using topology prediction and molecular modelling to understand their pathogenicity

Schoeman, D.; Cloete, R.; Fielding, B.

10.1101/2021.03.08.434384 — bioinformatics — Posted on 2021-03-08

3746 Comparative host interactomes of the SARS-CoV-2 nonstructural protein 3 and human coronavirus homologs

Almasy, K. M.; Davies, J. P.; Plate, L.

10.1101/2021.03.08.434440 — biochemistry — Posted on 2021-03-08

3747 Sialic acid-Dependent Binding and Viral Entry of SARS-CoV-2

Nguyen, L.; McCord, K. A.; Bui, D. T.; Bouwman, K. A.; Kitova, E. N.; Kumawat, D.; Daskan, G. C.; Tomris, I.; Han, L.; Chopra, P.; Yang, T.-J.; Williows, S. D.; Lowary, T. L.; West, L. J.; Hsu, S.-T. D.; Tompkins, S. M.; Boons, G.-J.; Mason, A. L.; de Vries, R. P.; Macauley, M. S.; Klassen, J. S.

10.1101/2021.03.08.434228 — biochemistry — Posted on 2021-03-08

3748 SARS-CoV-2 evolution in animals suggests mechanisms for rapid variant selection

Bashor, L.; Gagne, R. B.; Bosco-Lauth, A.; Bowen, R.; Stenglein, M.; VandeWoude, S.

10.1101/2021.03.05.434135 — evolutionary biology — Posted on 2021-03-08

3749 Human nasal and lung tissues infected ex vivo with SARS-CoV-2 provide insights into differential tissue-specific and virus-specific innate immune responses in the upper and lower respiratory tract

Alfi, O.; Yakirevich, A.; Wald, O.; Wandel, O.; Izhar, U.; Oiknine-Djian, E.; Nevo, Y.; Elgavish, S.; Dagan, E.; Madgar, O.; Feinmesser, G.; Pikarsky, E.; Bronstein, M.; Vorontsov, O.; Jonas, W.; Ives, J.; Walter, J.; Zakay-Rones, Z.; Oberbaum, M.; Panet, A.; Wolf, D. G.

10.1101/2021.03.08.434404 — microbiology — Posted on 2021-03-08

3750 Signal processing basics applied to Ecoacoustics

Sanchez-Gendriz, I.

10.1101/2021.01.26.428328 — scientific communication and education — Posted on 2021-03-08

3751 Temporal correlation between oscillating force dipoles drives 3D single cell migration

Godeau, A. L.; Leoni, M.; Comelles, J.; Delanoe-Ayari, H.; Ott, A.; Harlepp, S.; Sens, P.; Riveline, D.

10.1101/2020.05.07.081984 — biophysics — Posted on 2021-03-08

3752 A comparative recombination analysis of human coronaviruses and implications for the SARS-CoV-2 pandemic

Pollett, S.; Conte, M. A.; Sanborn, M. A.; Jarman, R. G.; Lidl, G. M.; Modjarrad, K.; Maljkovic Berry, I.

10.1101/2021.03.07.434287 — genomics — Posted on 2021-03-08

3753 Characterization of RNA content in individual phase-separated coacervate microdroplets

Wollny, D.; Vernot, B.; Wang, J.; Hondele, M.; Hyman, A. A.; Weis, K.; Camp, J. G.; Tang, T.-Y. D.; Treutlein, B.

10.1101/2021.03.08.434405 — genomics — Posted on 2021-03-08

3754 Using coverage-based rarefaction to infer non-random species distributions

Engel, T.; Blowes, S. A.; McGlinn, D. J.; May, F.; Gotelli, N. J.; McGill, B. J.; Chase, J. M.

10.1101/2020.04.14.040402 — ecology — Posted on 2021-03-08

3755 Co-culture of type I and type II pneumocytes as a model of alveolar epithelium

Brookes, O.; Boland, S.; Lai-Kuen, R.; Baeza-Squiban, A.

10.1101/2021.03.08.434368 — cell biology — Posted on 2021-03-08

3756 An unusually long 5'UTR of ATP dependent cold shock DEAD-box RNA helicase gene csdA negatively regulates its own expression in Escherichia coli

Jana, S.; Datta, P. P.

10.1101/2021.03.08.434349 — molecular biology — Posted on 2021-03-08

3757 The neuropeptides VIP and PACAP inhibit SARS-CoV-2 replication in monocytes and lung epithelial cells, decrease the production of proinflammatory cytokines, and VIP levels are associated with survival in severe COVID-19 patients.

Temerozo, J. R.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Pao, C. R. R.; de Freitas, C. S.; Dias, S. d. S. G.; Ferreira, A. C.; Mattos, M.; Soares, V. C.; Teixeira, L.; de Azevedo-Quintanilha, I. G.; Hottz, E. D.; Kurtz, P.; Bozza, F. A.; Bozza, P. T.; Souza, T. M. L.; Bou-Habib, D. C.

10.1101/2020.07.25.220806 — microbiology — Posted on 2021-03-08

3758 Recurrent emergence and transmission of a SARS-CoV-2 Spike deletion H69/V70

Kemp, S.; Meng, B.; Ferreira, I.; Datir, R.; Harvey, W.; Collier, D.; COVID-19 Genomics UK (COG-UK) consortium, ; Papa, G.; Carabelii, A.; Lytras, S.; Kenyon, J.; Lever, A.; James, L.; Robertson, D. L.; Gupta, R. K.

10.1101/2020.12.14.422555 — microbiology — Posted on 2021-03-08

3759 Exosome-Mediated mRNA Delivery For SARS-CoV-2 Vaccination

Tsai, S. J.; Guo, C.; Sedgwick, A.; Kanagavelu, S.; Nice, J.; Shetty, S.; Landaverde, C.; Atai, N. A.; Gould, S. J.

10.1101/2020.11.06.371419 — immunology — Posted on 2021-03-08

3760 Beta and theta oscillations correlate with subjective time during musical improvisation in ecological and controlled settings: a single subject study

Farrugia, N.; Lamouroux, A.; Rocher, C.; Bouvet, J.; Lioi, G.

10.1101/2020.11.08.373217 — neuroscience — Posted on 2021-03-08

3761 Discrete dynamic model of the mammalian sperm acrosome reaction: the influence of acrosomal pH and biochemical heterogeneity

Aldana, A.; Carneiro, J.; Martinez-Mekler, G.; Darszon, A.

10.1101/2021.03.07.434290 — systems biology — Posted on 2021-03-08

3762 BCOR and BCORL1 mutations disrupt PRC1.1 repressive function in leukemia by unlinking the RING-PCGF1 enzymatic core from target genes

Schaefer, E. J.; Wang, W. C.; Meyer, C. A.; Cejas, P.; Gearhart, M. D.; Adelman, E. R.; Fares, I.; Apffel, A.; Lim, K.; Xie, Y.; Gibson, C. J.; Schenone, M.; Murdock, H. M.; Wang, E. S.; Gondek, L. P.; Carroll, M. P.; Vedula, R. S.; Winer, E. S.; Garcia, J. S.; Stone, R. M.; Luskin, M. R.; Carr, S. A.; Long, H. W.; Bardwell, V. J.; Figueroa, M. E.; Lindsley, R. C.

10.1101/2021.03.08.433705 — cancer biology — Posted on 2021-03-08

3763 Efficient graphene oxide coating improves cryo-EM sample preparation and data collection from tilted grids

Patel, A. B.; Toso, D.; Litvak, A.; Nogales, E.

10.1101/2021.03.08.434344 — biophysics — Posted on 2021-03-08

3764 Modeling the SARS-CoV-2 nsp1--5'-UTR complex via extended ensemble simulations

Sakuraba, S.; Qilin, X.; Kasahara, K.

10.1101/2021.02.24.432807 — biophysics — Posted on 2021-03-08

3765 Retention Time Prediction Using Neural Networks Increases Identifications in Crosslinking Mass Spectrometry

Giese, S. H.; Sinn, L. R.; Wegner, F.; Rappsilber, J.

10.1101/2021.03.08.432999 — bioinformatics — Posted on 2021-03-08

3766 Microfluidic Live-Imaging technology to perform research activities in 3D models

Capuzzo, A. M.; Vigo, D.

10.1101/2021.03.08.434339 — bioengineering — Posted on 2021-03-08

3767 Combinatorial patterns of gene expression changes contribute to variable expressivity of the developmental delay-associated 16p12.1 deletion

Jensen, M.; Tyryskhina, A.; Pizzo, L.; Smolen, C.; Das, M.; Huber, E.; Krishnan, A.; Girirajan, S.

10.1101/2021.03.06.434203 — genomics — Posted on 2021-03-08

3768 Domain dependent orchestrated regulation of bacterial growth, persistence and chemotaxis by an essential GTPase, CgtA, in Vibrio cholerae

Das, S.; Datta, P. P.

10.1101/2021.03.08.434341 — molecular biology — Posted on 2021-03-08

3769 CBL-C E3 ubiquitin ligase acts as a host defense to mediate ubiquitin-proteasomal degradation of enteropathogenic Escherichia coli Tir protein

Ryu, J.; Otsubo, R.; Ashida, H.; Iida, T.; Abe, A.; Sasakawa, C.; Mimuro, H.

10.1101/2021.03.08.434331 — microbiology — Posted on 2021-03-08

3770 Experimental susceptibility of North American raccoons (Procyon lotor) and striped skunks (Mephitis mephitis) to SARS-CoV-2

Francisco, R.; Hernandez, S. M.; Mead, D. G.; Adcock, K. G.; Burke, S. C.; Nemeth, N. M.; Yabsley, M. J.

10.1101/2021.03.06.434226 — microbiology — Posted on 2021-03-08

3771 Pediatric nasal epithelial cells are less permissive to SARS-CoV-2 replication compared to adult cells

Zhu, Y.; Chew, K. Y.; Karawita, A. C.; Yamamoto, A.; Labzin, L. L.; Yarlagadda, T.; Khromykh, A. A.; Stocks, C. J.; Xia, Y.; Kollmann, T. R.; Martino, D.; Kicic, A.; Bielefeldt-Ohmann, H.; Bowen, A. C.; Sly, P. D.; Spann, K. M.; Short, K. R.

10.1101/2021.03.08.434300 — microbiology — Posted on 2021-03-08

3772 Predicting COVID-19 Severity with a Specific Nucleocapsid Antibody plus Disease Risk Factor Score

Sen, S.; Sanders, E. C.; Gabriel, K. N.; Miller, B. M.; Isoda, H. M.; Salcedo, G. S.; Garrido, J. E.; Dyer, R. P.; Nakajima, R.; Jain, A.; Caldaruse, A.-M.; Santos, A. M.; Bhuvan, K.; Tifrea, D. F.; Ricks-Oddie, J. L.; Felgner, P. L.; Edwards, R. A.; Majumdar, S.; Weiss, G. A.

10.1101/2020.10.15.341743 — immunology — Posted on 2021-03-08

3773 SARS-COV-2 RBD Oral Vaccine Boosted by Mucosal Immune Adjuvant LTB26 via DCs and B Cells Activation in Mice

Ma, Y.; Shi, Q.; Wang, Q.; Chen, S.; Gan, S.; Fang, C.; Shen, Y.; Jiang, M.; Lin, T.; Song, F.

10.1101/2020.04.06.025981 — immunology — Posted on 2021-03-08

3774 Control of Parallel Hippocampal Output Pathways by Amygdalar Long-Range Inhibition

AlSubaie, R.; Wee, R. W. S.; Ritoux, A.; Mishchanchuk, K.; Regester, D.; MacAskill, A. F.

10.1101/2021.03.08.434367 — neuroscience — Posted on 2021-03-08

3775 Spatial patterns in functional brain connectomes reflect acute and chronic cannabis use.

Ramaekers, J.; Mason, N. L.; Toennes, S.; Theunissen, E.; Amico, E.

10.1101/2021.03.08.434333 — neuroscience — Posted on 2021-03-08

3776 Atrx deletion impairs cGAS-STING signaling and increases response to radiation and oncolytic herpesvirus in sarcoma

Floyd, W.; Pierpoint, M.; Su, C.; Luo, L.; Deland, K.; Wisdom, A. J.; Zhu, D.; Ma, Y.; DeWitt, S. B.; Williams, N. T.; Somarelli, J. A.; Corcoran, D. L.; Eward, W. C.; Cardona, D. M.; Kirsch, D. G.

10.1101/2021.03.08.434225 — cancer biology — Posted on 2021-03-08

3777 Cyclodextrins increase membrane tension and are universal activators of mechanosensitive channels

Cox, C.; Zhang, Y.; Zhou, Z.; Walz, T.; Martinac, B.

10.1101/2021.03.08.434340 — biophysics — Posted on 2021-03-08

3778 A Macro-scale Comparison Algorithm for Analysis of TCR Repertoire Completeness

Esponda, F.; Sulc, P.; Blattman, J.; Forrest, S.

10.1101/2021.03.07.434284 — bioinformatics — Posted on 2021-03-08

3779 Ameliorating Emotional Attention through Modulation of Neural Oscillations with Transcranial Alternating Current Stimulation

Liu, S.; He, Y.; Guo, D.; Liu, X.; Hao, X.; Hu, P.; Ming, D.

10.1101/2021.03.08.434260 — bioengineering — Posted on 2021-03-08

3780 GFI1 cooperates with IKAROS/IKZF1 to activate gene expression in T-cell acute lymphoblastic leukemia

Engel, M. E.; Sun, W.; Guo, J.; McClellan, D.; Poeschla, A.; Bareyan, D.; Casey, M. J.; Cairns, B. R.; Tantin, D.

10.1101/2021.03.08.434336 — biochemistry — Posted on 2021-03-08

3781 In search of an honest butterfly: sexually selected wing coloration and reproductive traits from wild populations of the cabbage white butterfly

Espeset, A. E.; Forister, M. L.

10.1101/2021.03.07.434307 — ecology — Posted on 2021-03-08

3782 Simultaneous equations modelling of communities with interacting species networks

Porto, M.; Beja, P.

10.1101/2021.03.07.434253 — ecology — Posted on 2021-03-08

3783 The DMT and Psilocin Treatment Changes CD11b+ Activated Microglia Immunological Phenotype

Kozlowska, U. J.; Klimczak, A.; Wiatr, K.; Figiel, M.

10.1101/2021.03.07.434103 — cell biology — Posted on 2021-03-08

3784 Mitotic H3K9ac is controlled by phase-specific activity of HDAC2, HDAC3 and SIRT1

Gandhi, S.; Mitterhoff, R.; Rapoport, R.; Eden, S.; Goren, A.; Simon, I.

10.1101/2021.03.08.434337 — cell biology — Posted on 2021-03-08

3785 Drug development of an affinity enhanced, broadly neutralizing heavy chain only antibody that restricts SARS-CoV-2 in hamsters

Schepens, B.; van Schie, L.; Nerinckx, W.; Roose, K.; Van Breedam, W.; Fijalkowska, D.; Devos, S.; Weyts, W.; De Cae, S.; Vanmarcke, S.; Lonigro, C.; Eeckhaut, H.; Van Herpe, D.; Borloo, J.; Oliveira, A. F.; Catani, J. P.; Creytens, S.; De Vlieger, D.; Michielsen, G.; Marchan, J. C. Z.; Moschonas, G. D.; Rossey, I.; Sedeyn, K.; Van Hecke, A.; Zhang, X.; Langendries, L.; Jacobs, S.; ter Horst, S.; Seldeslachts, L.; Liesenborghs, L.; Boudewijns, R.; Tibaut, H. J.; Dallmeier, K.; Vande Velde, G.; Weynand, B.; Beer, J.; Schnepf, D.; Ohnemus, A.; Foo, C. S.-Y.; Abdelnabi, R.; Maes, P.; Kaptein, S.

10.1101/2021.03.08.433449 — molecular biology — Posted on 2021-03-08

3786 Deletion disrupts a conserved antibody epitope in a SARS-CoV-2 variant of concern

Rennick, L. L.; Robinson-McCarthy, L. R.; Nambulli, S.; Duprex, W. P.; McCarthy, K. R.

10.1101/2021.03.05.434168 — microbiology — Posted on 2021-03-08

3787 A Peek into the Plasmidome of Global Sewage

Kirstahler, P.; Teudt, F.; Otani, S.; Aarestrup, F. M.; Pamp, S. J.

10.1101/2021.03.08.434362 — microbiology — Posted on 2021-03-08

3788 Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies

Muecksch, F.; Weisblum, Y.; Barnes, C.; Schmidt, F.; Schaefer-Babajew, D.; Lorenzi, J.; Flyak, A.; DeLaitsch, A.; Huey-Tubman, K.; Hou, S.; Schiffer, C.; Gaebler, C.; Wang, Z.; Da Silva, J.; Poston, D.; Finkin, S.; Cho, A.; Cipolla, M.; Oliveira, T.; Millard, K.; Ramos, V.; Gazumyan, A.; Rutkowska, M.; Caskey, M.; Nussenzweig, M.; Bjorkman, P.; Hatziioannou, T.; Bieniasz, P.

10.1101/2021.03.07.434227 — microbiology — Posted on 2021-03-08

3789 Systematic exploration of Escherichia coli phage-host interactions with the BASEL phage collection

Maffei, E.; Shaidullina, A.; Burkolter, M.; Druelle, V.; Willi, L.; Estermann, F.; Michaelis, S.; Hilbi, H.; Thaler, D. S.; Harms, A.

10.1101/2021.03.08.434280 — microbiology — Posted on 2021-03-08

3790 Development and pre-clinical evaluation of Newcastle disease virus-vectored SARS-CoV-2 intranasal vaccine candidate

Fernandez-Diaz, M.; Calderon, K.; Rojas-Neyra, A.; Vakharia, V. N.; Choque-Guevara, R.; Montalvan, A.; Poma-Acevedo, A.; Rios-Matos, D.; Agurto-Arteaga, A.; Cauti-Mendoza, M. D. G.; Perez-Martinez, N.; Isasi-Rivas, G.; Tataje-Lavanda, L.; Palomino, M.; Bailon, H.; Sernaque-Aguilar, Y.; Ygnacio-Aguire, F.; Criollo-Orozco, M.; Huaccachi-Gonzalez, E.; Delgado-Ccancce, E.; Villanueva-Perez, D.; Montesinos-Millan, R.; Gutierrez-Manchay, K.; Pauyac-Antezana, K.; Ramirez-Ortiz, I.; Quinones Garcia, M. S.; Cauna-Orocollo, Y.; Vallejos-Sanchez, K.; Rios-Angulo, A. A.; Nunez-Fernandez, D.; Salguedo-Boho

10.1101/2021.03.07.434276 — immunology — Posted on 2021-03-08

3791 Regulation of coordinated muscular relaxation by a pattern-generating intersegmental circuit

Hiramoto, A.; Jonaitis, J.; Niko, S.; Kohsaka, H.; Fetter, R. D.; Cardona, A.; Pulver, S. R.; Nose, A.

10.1101/2021.03.08.434356 — neuroscience — Posted on 2021-03-08

3792 The developing brain structural and functional connectome fingerprint

10.1101/2021.03.08.434357 — neuroscience — Posted on 2021-03-08

3793 Differential Roles of Positive and Negative Valence Systems in the Development of Post-Traumatic Stress Psychopathology

Ben-Zion, Z.; Shany, O.; Admon, R.; Keynan, N. J.; Avisdris, N.; Reznik Balter, S.; Shalev, A. Y.; Liberzon, I.; Hendler, T.

10.1101/2021.03.08.434335 — neuroscience — Posted on 2021-03-08

3794 Knowledge, Attitude and Practices towards COVID-19 Guidelines among Students in Bangladesh

Kumar, B.; Pinky, S. D.; Nurudden, A. M.

10.1101/2021.03.07.433083 — scientific communication and education — Posted on 2021-03-08

3795 AN INTEGRATIVE APPROACH DISCOVERS A NOVEL ANTI-LEUKEMIC PEPTIDE FROM HUMAN MILK

Chiangjong, W.; Panachan, J.; Vanichapol, T.; Pongsakul, N.; Lerksuthirat, T.; Nuntnarumit, P.; Supapannachart, S.; Srisomsap, C.; Svasti, J.; Hongeng, S.; Chutipongtanate, S.

10.1101/2021.03.07.434306 — pharmacology and toxicology — Posted on 2021-03-08

3796 FisB relies on homo-oligomerization and lipid-binding to catalyze membrane fission in bacteria

Landajuela, A.; Braun, M.; Rodrigues, C. D. A.; Martinez-Calvo, A.; Doan, T.; Horenkamp, F. A.; Andronicos, A.; Shteyn, V.; Williams, N. D.; Lin, C.; Wingreen, N. S.; Rudner, D. Z.; Karatekin, E.

10.1101/2020.09.25.313023 — biophysics — Posted on 2021-03-08

3797 Clustering-based time series analysis on insulin response in the blood-brain barrier

Kalari, K. R.; Wang, Z.; Tang, X.; Swaminathan, S. K.; Kandimalla, K. K.

10.1101/2021.03.07.434315 — bioinformatics — Posted on 2021-03-08

3798 Alternating lysis and lysogeny is a winning strategy in bacteriophages due to Parrondo's Paradox

Cheong, K. H.; Wen, T.; Benler, S.; Koonin, E. V.

10.1101/2021.03.07.434273 — bioinformatics — Posted on 2021-03-08

3799 Revision and annotation of DNA barcode records for marine invertebrates: report of the 8th iBOL conference hackathon

Radulovici, A. E.; Vieira, P. E.; Duarte, S.; Teixeira, M. A. L.; Borges, L. M. S.; Deagle, B.; Majaneva, S.; Redmond, N.; Schultz, J. A.; Costa, F. O.

10.1101/2021.03.07.434272 — genetics — Posted on 2021-03-08

3800 U5 snRNA interactions with exons ensure splicing precision

Artemyeva-Isman, O. V.; Porter, A. C. G.

10.1101/2021.03.07.434243 — genetics — Posted on 2021-03-08

3801 Hibernation slows epigenetic aging in yellow-bellied marmots

Pinho, G. M.; Martin, J. G. A.; Farrell, C.; Haghani, A.; Zoller, J. A.; Zhang, J.; Snir, S.; Pellegrini, M.; Wayne, R. K.; Blumstein, D. T.; Horvath, S.

10.1101/2021.03.07.434299 — evolutionary biology — Posted on 2021-03-08

3802 Adaptive evolution of Moniliophthora PR-1 proteins towards its pathogenic lifestyle

Vasconcelos, A. A.; Jose, J.; Tokimatu Filho, P. M.; Camargo, A. P.; Teixeira, P. J. P. L.; Thomazella, D. P. T.; Prado, P. F. V.; Fiorin, G. L.; Carazzolle, M. F.; Pereira, G. A. G.; Baroni, R. M.

10.1101/2021.03.07.434232 — evolutionary biology — Posted on 2021-03-08

3803 Impaired Cx43 gap junction endocytosis causes cardiovascular defects in zebrafish

Hyland, C.; Mfarej, M.; Hiotis, G.; Lancaster, S.; Novak, N.; Iovine, M. K.; Falk, M. M.

10.1101/2021.03.07.434329 — cell biology — Posted on 2021-03-08

3804 A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system

Shen, Y.; Jiang, L.; Iyer, V. S.; Raposo, B.; Boddul, S. V.; Kasza, Z.; Wermeling, F.

10.1101/2021.03.08.434360 — immunology — Posted on 2021-03-08

3805 Aberrant Temporal-spatial Patterns to Sad expressions in Major Depressive Disorders via Hidden Markov Model

Dai, Z.; Zhang, S.; Zhou, H.; Wang, X.; Wang, H.; Yao, Z.; Lu, Q.

10.1101/2021.03.07.433735 — neuroscience — Posted on 2021-03-08

3806 Structured Modulations of Ongoing Variability by Task and Development

Naik, S.; Adibpour, P.; Dubois, J.; Dehaene-Lambertz, G.; Battaglia, D.

10.1101/2021.03.07.434162 — neuroscience — Posted on 2021-03-08

3807 Prospective Identification of Ictal Electroencephalogram

Yang, Y.; Truong, N. D.; Maher, C.; Nikpour, A.; Kavehei, O.

10.1101/2021.03.07.433990 — neuroscience — Posted on 2021-03-08

3808 Medulla glutamatergic neurons control wake-sleep transitions

Teng, S.; Zhen, F.; Schalchli, J. C.; Chen, X.; Jin, H.; Wang, L.; Peng, Y.

10.1101/2021.03.07.434263 — neuroscience — Posted on 2021-03-08

3809 In vitro neuronal networks show bidirectional axonal conduction with antidromic action potentials effectively depolarizing the soma

Mateus, J.; Lopes, C.; Aroso, M.; Costa, A.; Geros, A.; Pereira, A.; Meneses, J.; Faria, P.; Neto, E.; Lamghari, M.; Sousa, M.; Aguiar, P.

10.1101/2021.03.07.434278 — neuroscience — Posted on 2021-03-08

3810 Hypothalamic perineuronal nets are regulated by sex and dietary interventions

Zhang, N.; Yan, Z.; Liu, H.; Yu, M.; He, Y.; Liu, H.; Liang, C.; Tu, L.; Wang, L.; Yin, N.; Han, J.; Scarcelli, N.; Yang, Y.; Wang, C.; Zeng, T.; Chen, L.; Xu, Y.

10.1101/2021.03.07.434286 — neuroscience — Posted on 2021-03-08

3811 Probing adaptation and spontaneous firing in human auditory-nerve fibers with far-field peri-stimulus time responses

Huet, A.; Batrel, C.; Dubernard, X.; Kleiber, J.-C.; Desmadryl, G.; Venail, F.; Liberman, C.; Nouvian, R.; Puel, J.-L.; Bourien, J.

10.1101/2021.03.08.434366 — neuroscience — Posted on 2021-03-08

3812 Expansion-Assisted Iterative-FISH defines lateral hypothalamus spatio-molecular organization

Wang, Y.; Eddison, M.; Fleishman, G.; Weigert, M.; Xu, S.; Henry, F. E.; Wang, T.; Lemire, A. L.; Schmidt, U.; Yang, H.; Rokicki, K.; Goina, C.; Svoboda, K.; Myers, E. W.; Saalfeld, S.; Korff, W.; Sternson, S. M.; Tillberg, P. W.

10.1101/2021.03.08.434304 — neuroscience — Posted on 2021-03-08

3813 Is galactose a hormetic sugar? Evidence from rat hippocampal redox regulatory network

Homolak, J.; Babic Perhoc, A.; Knezovic, A.; Kodvanj, I.; Virag, D.; Osmanovic Barilar, J.; Riederer, P.; Salkovic-Petrisic, M.

10.1101/2021.03.08.434370 — neuroscience — Posted on 2021-03-08

3814 The effects of insecticide seed treatments on green peach aphid Myzus persicae (Sulzer) (Homoptera: Aphididae) parasitism by Aphidius colemani Viereck (Hymenoptera: Aphidiidae) and predation by Mallada signatus (Schneider) (Neuroptera: Chrysopidae)

Ward, S. E.; Hoffmann, A. A.; Van Helden, M.; Umina, P. A.

10.1101/2021.03.07.434302 — zoology — Posted on 2021-03-08

3815 Combined MEK and STAT3 inhibition reprograms the tumor microenvironment to overcome immunotherapy resistance in pancreatic cancer

Datta, J.; Lamichhane, P.; Dai, X.; Mehra, S.; Dosch, A. R.; Messagio, F.; Umland, O.; Willobee, B. A.; VanSaun, M.; Hosein, P. J.; Nagathihalli, N.; Merchant, N.

10.1101/2021.03.07.434236 — cancer biology — Posted on 2021-03-08

3816 Label free sensing with Terahertz multiple ring resonators

Zhe, L.; Bai, X.

10.1101/2021.03.07.434261 — biophysics — Posted on 2021-03-08

3817 Nanoscale organization of Actin Filaments in the Red Blood Cell Membrane Skeleton

Nowak, R. B.; Alimohamadi, H.; Pestonjamasp, K.; Rangamani, P.; Fowler, V. M.

10.1101/2021.03.07.434292 — biophysics — Posted on 2021-03-08

3818 Temperature-dependent Self assembly of biofilaments during red blood cell sickling

Behera, A.; Sharma, O.; Paul, D.; Sain, A.

10.1101/2021.03.07.433773 — biophysics — Posted on 2021-03-08

3819 GraphBreak: Network Community detection and annotation in biomedical regulatory informatics context

Singh, A. N.

10.1101/2021.03.07.434249 — bioinformatics — Posted on 2021-03-08

3820 Dissecting Transition Cells from Single-Cell Transcriptome Data through Multiscale Stochastic Dynamics

Zhou, P.; Wang, S.; Li, T.; Nie, Q.

10.1101/2021.03.07.434281 — bioinformatics — Posted on 2021-03-08

3821 A network regularized linear model to infer spatial expression pattern for singlecells

Gu, C.; liu, z.

10.1101/2021.03.07.434296 — bioinformatics — Posted on 2021-03-08

3822 An Investigation into Patient-Specific 3D Printed Titanium Stents and the use of Etching to Overcome Selective Laser Melting Design Constraints.

McGee, O. M.; Geraghty, S.; Hughes, C.; Jamshidi, P.; Kenny, D. P.; Attallah, M. M.; Lally, C. M.

10.1101/2021.03.07.434132 — bioengineering — Posted on 2021-03-08

3823 Multichromatic Near-Infrared Imaging to Assess Interstitial Lymphatic and Venous Uptake In Vivo

Bernard, F. C.; Kaiser, J.; Raval, S. K.; Nepiyushchikh, Z. V.; Doan, T. N.; Willett, N. J.; Dixon, J. B.

10.1101/2021.03.07.434298 — bioengineering — Posted on 2021-03-08

3824 The chromatin factor ROW cooperates with BEAF-32 in regulating long-range genes

Herman, N.; Kadener, S.; Shifman, S.

10.1101/2021.03.08.434270 — genomics — Posted on 2021-03-08

3825 Mito-nuclear variation in transgenerational and reproductive effects of amino acid and lipid nutrition

Dobson, A.; Kumpitsch, L.; Langer, L.; Voigt, E.; Dowling, D. K.; Reinhardt, K.

10.1101/2021.03.07.434274 — genetics — Posted on 2021-03-08

3826 The developmental hourglass model is applicable to the spinal cord

Mukaigasa, K.; Sakuma, C.; Yaginuma, H.

10.1101/2021.03.08.434342 — evolutionary biology — Posted on 2021-03-08

3827 A feedback mechanism mediated by myosin II-dependent apical targeting of Rab11 vesicles reinforces apical constriction

Chen, W.; He, B.

10.1101/2021.03.07.434309 — developmental biology — Posted on 2021-03-08

3828 Fluidics System for Resolving Concentration-Dependent Effects of Dissolved Gases on Tissue Metabolism

Sweet, I. R.; Hurley, J. B.; Kamat, V.; Robbings, B. M.; Bube, K. P.; Jung, S.-R.; Kelly, J.

10.1101/2021.03.07.434330 — cell biology — Posted on 2021-03-08

3829 Nitric oxide synthases from photosynthetic organisms improve growth and confer nitrosative stress tolerance in E. coli. Insights on the pterin cofactor

Correa-Aragunde, N.; Nejamkin, A.; Del Castello, F.; Foresi, N.; Lamattina, L.

10.1101/2021.03.07.434255 — microbiology — Posted on 2021-03-08

3830 Increased disease burden in Interleukin-3 deficient mice after Mycobacterium tuberculosis and herpes simplex virus infections

Kunnath-Velayudhan, S.; Ng, T. W.; Saini, N. K.; Goldberg, M. F.; Arora, P.; Xu, J.; Kim, J.; Herold, B. C.; Chan, J.; Jacobs, W. R.; Porcelli, S. A.

10.1101/2021.03.07.434271 — immunology — Posted on 2021-03-08

3831 Genetic inactivation of SARM1 axon degeneration pathway improves outcome trajectory after experimental traumatic brain injury based on pathological, radiological, and functional measures

Bradshaw, D. V.; Knutsen, A. K.; Korotcov, A.; Sullivan, G. M.; Radomski, K. L.; Dardzinski, B. J.; Zi, X.; McDaniel, D. P.; Armstrong, R. C.

10.1101/2021.03.07.434264 — neuroscience — Posted on 2021-03-08

3832 Multiple bouts of high-intensity interval exercise reverse age-related functional connectivity disruptions without affecting motor learning in older adults

Greeley, B.; Chau, B.; Jones, C. B.; Neva, J. L.; Kraeutner, S. N.; Campbell, K. L.; Boyd, L. A.

10.1101/2021.03.07.434269 — neuroscience — Posted on 2021-03-08

3833 Single cell analysis of the aging hypothalamus

Hajdarovic, K. H.; Yu, D.; Hassell, L.-A.; Evans, S. A.; Neretti, N.; Webb, A. E.

10.1101/2021.03.07.434282 — neuroscience — Posted on 2021-03-08

3834 BioISO: an objective-oriented application for assisting the curation of genome-scale metabolic models

Cruz, F.; Capela, J.; Ferreira, E. C.; Rocha, M.; Dias, O.

10.1101/2021.03.07.434259 — systems biology — Posted on 2021-03-08

3835 Single-cell RNA-seq revealed the role of Alkbh5 in reproduction

Shen, X.; Xie, G.

10.1101/2021.03.06.434224 — bioinformatics — Posted on 2021-03-08

3836 Multiplexed Ion Beam Imaging Readout of Single-Cell Immunoblotting

Lomeli, G.; Bosse, M.; Bendall, S. C.; Angelo, M.; Herr, A. E.

10.1101/2021.03.06.434187 — bioengineering — Posted on 2021-03-08

3837 In vivo co-registered hybrid-contrast imaging by successive photoacoustic tomography and magnetic resonance imaging

Zhang, S.; Qi, L.; Li, X.; Liang, Z.; Wu, J.; Huang, S.; Liu, J.; Zhuang, Z.; Feng, Y.; Feng, Q.; Chen, W.

10.1101/2021.03.06.434031 — bioengineering — Posted on 2021-03-08

3838 A Kiosk Station for the Assessment of Multiple Cognitive Domains and Enrichment of Monkeys

Womelsdorf, T.; Thomas, C.; Neumann, A.; Watson, M.; Banaie Boroujeni, K.; Hassani, S. A.; Parker, J. M.; Hoffman, K. L.

10.1101/2021.03.06.434198 — animal behavior and cognition — Posted on 2021-03-08

3839 Spontaneously Hypertensive Rat substrains show differences in premorbid addiction vulnerability traits and cocaine self-administration: Implications for a novel rat reduced complexity cross

Kantak, K. M.; Stots, C.; Mathieson, E.; Bryant, C. D.

10.1101/2021.03.06.434216 — animal behavior and cognition — Posted on 2021-03-08

3840 Refining Convergent Rate Analysis with Topology in Mammalian Longevity and Marine Transitions

Treaster, S.; Daane, J. M.; Harris, M.

10.1101/2021.03.06.434197 — genomics — Posted on 2021-03-08

3841 Temperature-dependent use of daily torpor attenuates the energetic consequences of habitat selection for a widespread bat

Alston, J. M.; Dillon, M. E.; Keinath, D. A.; Abernethy, I. M.; Goheen, J. R.

10.1101/2021.03.06.434212 — ecology — Posted on 2021-03-08

3842 An Automated Radio-Telemetry System (ARTS) for Monitoring Small Mammals

Wallace, G. N.; Elden (nee Gorinshteyn), M.; Boucher (nee Sheely), R.; Phelps, S.

10.1101/2021.03.06.434221 — ecology — Posted on 2021-03-08

3843 Elevated N-glycosylation of immunoglobulin G variable regions in myasthenia gravis highlights a commonality across autoantibody-associated diseases

Mandel-Brehm, C.; Fichtner, M. L.; Jiang, R.; Winton, V. J.; Vazquez, S. E.; Pham, M. C.; Hoehn, K. B.; Kelleher, N. L.; Nowak, R. J.; Kleinstein, S. H.; Wilson, M. R.; DeRisi, J. L.; OConnor, K. C.

10.1101/2021.03.06.434199 — immunology — Posted on 2021-03-08

3844 Odor-evoked Increases in Spiking Variability in the Olfactory Bulb

Ly, C.; Barreiro, A. K.; Gautam, S. H.; Shew, W. L.

10.1101/2021.03.05.434131 — neuroscience — Posted on 2021-03-08

3845 Cross-modal perceptual enhancement of unisensory targets is uni-directional and does not affect temporal expectations

Ball, F.; Nentwich, A.; Noesselt, T.

10.1101/2021.03.06.434204 — neuroscience — Posted on 2021-03-08

3846 Sleep deprivation exacerbates seizures and diminishes GABAergic tonic inhibition

Kondru, S. S.; Pan, Y.; Wallace, E. P.; Pfammatter, J.; Jones, M. V.; Maganti, R.

10.1101/2021.03.06.434210 — neuroscience — Posted on 2021-03-08

3847 Limb apparent motion perception: modification by tDCS, and clinically or experimentally altered bodily states

Saetta, G.; Ho, J.; Bekrater-Bodmann, R.; Brugger, P.; Dijkerman, C.; Lenggenhager, B.

10.1101/2021.03.06.433957 — neuroscience — Posted on 2021-03-08

3848 Inhibiting microglia proliferation after spinal cord injury improves recovery in mice and nonhuman primates

POULEN, G.; ALOY, E.; BRINGUIER, C. M.; MESTRE-FRANCES, N.; ARTUS, E.; CARDOSO, M.; PEREZ, J.-C.; GOZE-BAC, C.; BOUKHADDAOUI, H.; LONJON, N.; GERBER, Y. N.; PERRIN, F. E.

10.1101/2021.03.06.434049 — neuroscience — Posted on 2021-03-08

3849 Lag structure of BOLD signals within white matter in resting-state fMRI

Guo, B.; Zhou, F.; Li, M.; Gore, J. C.

10.1101/2021.03.06.434206 — neuroscience — Posted on 2021-03-08

3850 Context dependency of time-based event-related expectations for different modalities

Ball, F.; Andreca, J.; Noesselt, T.

10.1101/2021.03.06.434208 — neuroscience — Posted on 2021-03-08

3851 Minimal interplay between explicit knowledge, dynamics of learning and temporal expectations in different, complex uni- and multisensory contexts

Ball, F.; Spuerck, I.; Noesselt, T.

10.1101/2021.03.06.434202 — neuroscience — Posted on 2021-03-08

3852 Smartphone-assisted real-time estimation of chlorophyll and carotenoid contents in spinach following the inversion of red and green color features

Agarwal, A.; Dongre, P. K.; Dutta Gupta, S.

10.1101/2021.03.06.434237 — plant biology — Posted on 2021-03-08

3853 Conditional Stomatal Closure in a Fern Shares Molecular Features with Flowering Plant Active Stomatal Responses

Plackett, A. R. G.; Emms, D. M.; Kelly, S.; Hetherington, A. M.; Langdale, J. A.

10.1101/2021.03.06.434194 — plant biology — Posted on 2021-03-08

3854 The dynamics of cell-free DNA from urine and blood after a full marathon

Shishikura, Y.; Tokinoya, K.; Aita, Y.; Sekine, N.; Sugasawa, T.; Yoshida, Y.; Kosaki, K.; Kumamoto, S.; Ishikura, K.; Kuji, T.; Kawakami, Y.; Nabekura, Y.; Maeda, S.; Takekoshi, K.

10.1101/2021.03.06.434188 — physiology — Posted on 2021-03-08

3855 Network diffusion for scalable embedding of massive single-cell ATAC-seq data

Dong, K.; Zhang, S.

10.1101/2021.03.05.434093 — bioinformatics — Posted on 2021-03-08

3856 Evotuning protocols for Transformer-based variant effect prediction on multi-domain proteins

Yamaguchi, H.; Saito, Y.

10.1101/2021.03.05.434175 — bioinformatics — Posted on 2021-03-08

3857 cinaR: A comprehensive R package for the dif-ferential analyses and functional interpretation of ATAC-seq data

Ucar, D.; Karakaslar, E. O.

10.1101/2021.03.05.434143 — bioinformatics — Posted on 2021-03-08

3858 Predicting functional consequences of mutations using molecular interaction network features

Ozturk, K.; Carter, H.

10.1101/2021.03.05.433991 — bioinformatics — Posted on 2021-03-08

3859 Longer study length, standardized sampling techniques, and broader geographic scope leads to higher likelihood of detecting stable abundance patterns in long term deer tick (Ixodes scapularis) studies

Christie, R.; Stack Whitney, K.; Perrone, J.; Bahlai, C.

10.1101/2021.03.06.434217 — bioinformatics — Posted on 2021-03-08

3860 Evaluate effects of multiple users in collaborative Brain-Computer Interfaces: A SSVEP study

Do, T.-T. N.; Huynh, T. T.

10.1101/2021.03.05.434173 — bioengineering — Posted on 2021-03-08

3861 Coordination of movement via complementary interactions of leaders and followers in termite mating pairs

Mizumoto, N.; Lee, S.-B.; Valentini, G.; Chouvenc, T.; Pratt, S. C.

10.1101/2021.03.05.434098 — animal behavior and cognition — Posted on 2021-03-08

3862 Moral Hazard Heterogeneity: Genes and Insurance Influence Smoking after a Health Shock

Biroli, P.; Zwyssig, L.

10.1101/2021.03.05.434163 — genetics — Posted on 2021-03-08

3863 Disentangling effects of climate and land use on biodiversity and ecosystem services - a multi-scale experimental design

Redlich, S.; Zhang, J.; Benjamin, C.; Singh Dhillon, M.; Englmeier, J.; Ewald, J.; Fricke, U.; Ganuza, C.; Haensel, M.; Hovestadt, T.; Kollmann, J.; Koellner, T.; Kuebert-Flock, C.; Kunstmann, H.; Menzel, A.; Moning, C.; Peters, W.; Riebl, R.; Rummler, T.; Rojas Botero, S.; Tobisch, C.; Uhler, J.; Uphus, L.; Mueller, J.; Steffan-Dewenter, I.

10.1101/2021.03.05.434036 — ecology — Posted on 2021-03-08

3864 Accounting for dispersal improves the understanding of species abundance patterns

Feng, X.; Qiao, H.

10.1101/2021.03.05.434182 — ecology — Posted on 2021-03-08

3865 Implicit and explicit learning of Bayesian priors differently impacts bias during perceptual decision-making

Thakur, V.; Basso, M. A.; Ditterich, J.; Knowlton, B.

10.1101/2021.03.05.434141 — neuroscience — Posted on 2021-03-08

3866 Neural responses to natural visual motion are spatially selective across the visual field, with selectivity differing across brain areas and task

Ki, J. J.; Dmochowski, J. P.; Touryan, J.; Parra, L. C.

10.1101/2021.03.05.434148 — neuroscience — Posted on 2021-03-08

3867 Parallel inference of hierarchical latent dynamics in two-photon calcium imaging of neuronal populations

Prince, L. Y.; Bakhtiari, S.; Gillon, C. J.; Richards, B. A.

10.1101/2021.03.05.434105 — neuroscience — Posted on 2021-03-08

3868 Dynamics of the auditory continuity illusion

Cao, Q.; Parks, N.; Goldwyn, J. H.

10.1101/2021.03.05.433617 — neuroscience — Posted on 2021-03-08

3869 A chloride efflux transporter OsBIRG1 regulates grain size and salt tolerance in rice

Ren, Z.; Bai, F.; Xu, J.; Wang, L.; Wang, X.; Zhang, Q.; Feng, C.; Niu, Q.; Zhang, L.; Li, M.; Song, J.; Bao, F.; Liu, L.; He, Y.; Ma, L.; Qiu, J.; Tian, W.; Hou, C.; Li, L.

10.1101/2021.03.07.434240 — plant biology — Posted on 2021-03-08

3870 Rapid and automated quantification of TDP-43 and FUS mislocalisation for screening of frontotemporal dementia and amyotrophic lateral sclerosis gene variants

Oyston, L. J.; Ubiparipovic, S.; Fitzpatrick, L.; Hallupp, M.; Boccanfuso, L. M.; Kwok, J. B.; Dobson-Stone, C.

10.1101/2021.03.07.433817 — molecular biology — Posted on 2021-03-08

3871 Combined landscape of single-nucleotide variants and copy-number alterations in clonal hematopoiesis

Saiki, R.; Momozawa, Y.; Nannya, Y.; Nakagawa, M. M.; Ochi, Y.; Yoshizato, T.; Terao, C.; Kuroda, Y.; Shiraishi, Y.; Chiba, K.; Tanaka, H.; Niida, A.; Imoto, S.; Matsuda, K.; Morisaki, T.; Murakami, Y.; Kamatani, Y.; Matsuda, S.; Kubo, M.; Miyano, S.; Makishima, H.; Ogawa, S.

10.1101/2021.03.05.433727 — cancer biology — Posted on 2021-03-08

3872 Learning Divisive Normalization in Primary Visual Cortex

Burg, M. F.; Cadena, S. A.; Denfield, G. H.; Walker, E. Y.; Tolias, A. S.; Bethge, M.; Ecker, A. S.

10.1101/767285 — neuroscience — Posted on 2021-03-08

3873 Artificial intelligence enables the identification and quantification of arbuscular mycorrhizal fungi in plant roots

Evangelisti, E.; Turner, C.; McDowell, A.; Shenhav, L.; Yunusov, T.; Gavrin, A.; Servante, E. K.; Quan, C.; Schornack, S.

10.1101/2021.03.05.434067 — plant biology — Posted on 2021-03-08

3874 Subfunctionalization of paralog transcription factors contributes to regulation of alkaloid pathway branch choice in Catharanthus roseus

Colinas, M.; Pollier, J.; Vaneechoutte, D.; Malat, D. G.; Schweizer, F.; De Clercq, R.; Guedes, J. G.; Martinez-Cortes, T.; Molina Hidalgo, F. J.; Sottomayor, M.; Vandepoele, K.; Goossens, A.

10.1101/2020.05.04.075671 — plant biology — Posted on 2021-03-08

3875 Activity Budget and Postural Behaviours in Orangutans on Bukit Merah Orang Utan Island for Assessing Captive Great Ape Welfare

Kamaluddin, S. N.; Matsuda, I.; Md-Zain, B. M.

10.1101/2020.12.15.422872 — animal behavior and cognition — Posted on 2021-03-08

3876 Multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology.

Shadrin, A. A.; Kaufmann, T.; van der Meer, D.; Palmer, C. E.; Makowski, C.; Loughnan, R. J.; Jernigan, T. L.; Seibert, T. M.; Hagler, D. J.; Smeland, O. B.; Chu, Y.; Lin, A.; Cheng, W.; Hindley, G.; Thompson, W. K.; Fan, C. C.; Holland, D.; Westlye, L. T.; Frei, O.; Andreassen, O. A.; Dale, A. M.

10.1101/2020.10.22.350298 — genetics — Posted on 2021-03-08

3877 Structural variants are a major source of gene expression differences in humans and often affect multiple nearby genes

Scott, A. J.; Chiang, C.; Hall, I. M.

10.1101/2021.03.06.434233 — genomics — Posted on 2021-03-08

3878 MicroRNA binding site variation is enriched inpsychiatric disorders

Geaghan, M. P.; Reay, W. R.; Cairns, M. J.

10.1101/2021.03.07.434312 — genetics — Posted on 2021-03-08

3879 Differential Expression of α,β, and γ Protocadherin Isoforms During Differentiation, Aging, and Cancer

West, M. D.; Labat, I.; Li, J.; Sim, P.; Janus, J.; Mangelson, H.; Sullivan, S.; Liachko, I.; Labhart, P.; Craske, M.; Egan, B.; Chapman, K. B.; Malik, N. N.; Larocca, D.; Sternberg, H.

10.1101/2021.03.07.434314 — developmental biology — Posted on 2021-03-08

3880 Multiplex-GAM: genome-wide identification of chromatin contacts yields insights not captured by Hi-C

Beagrie, R. A.; Thieme, C. J.; Annunziatella, C.; Baugher, C.; Zhang, Y.; Schueler, M.; Chiariello, A. M.; Bianco, S.; Kukalev, A.; Li, Y.; Kempfer, R.; Scialdone, A.; Welch, L. A.; Nicodemi, M.; Pombo, A.

10.1101/2020.07.31.230284 — molecular biology — Posted on 2021-03-08

3881 A global multiregional proteomic map of the human cerebral cortex

Guo, Z.; Shao, C.; Zhang, Y.; Qiu, W.; Li, W.; Zhu, W.; Yang, Q.; Huang, Y.; Pan, L.; Dong, Y.; Sun, H.; Xiao, X.; Sun, W.; Ma, C.; Zhang, L.

10.1101/2021.03.07.434254 — neuroscience — Posted on 2021-03-07

3882 Motor neuron boutons remodel through membrane blebbing

Fernandes, A. R.; Mendes, C. S.; Gomes, E. R.; Teodoro, R. O.

10.1101/2021.03.07.434250 — cell biology — Posted on 2021-03-07

3883 Understanding the Unique Advantage of Adolescents in Stochastic, Volatile Environments: Combining Reinforcement Learning and Bayesian Inference

Eckstein, M. K.; Master, S. L.; Dahl, R. E.; Wilbrecht, L.; Collins, A. G. E.

10.1101/2020.07.04.187971 — neuroscience — Posted on 2021-03-07

3884 Comparison study of sixteen differential abundance testing methods using two large Parkinson disease gut microbiome datasets

Wallen, Z. D.

10.1101/2021.02.24.432717 — genomics — Posted on 2021-03-07

3885 Within-sibship GWAS improve estimates of direct genetic effects

Howe, L. J.; Nivard, M. G.; Morris, T. T.; Hansen, A. F.; Rasheed, H.; Cho, Y.; Chittoor, G.; Lind, P. A.; Palviainen, T.; van der Zee, M. D.; Cheesman, R.; Mangino, M.; Wang, Y.; Li, S.; Klaric, L.; Ratliff, S. M.; Bielak, L. F.; Nygaard, M.; Reynolds, C. A.; Balbona, J. V.; Bauer, C. R.; Boomsma, D. I.; Baras, A.; Campbell, A.; Campbell, H.; Chen, Z.; Christofidou, P.; Dahm, C. C.; Dokuru, D. R.; Evans, L. M.; de Geus, E. J.; Giddaluru, S.; Gordon, S. D.; Harden, K. P.; Havdahl, A.; Hill, W. D.; Kerr, S. M.; Kim, Y.; Kweon, H.; Latvala, A.; Li, L.; Lin, K.; Martikainen, P.; Magnusson, P. K.;

10.1101/2021.03.05.433935 — genetics — Posted on 2021-03-07

3886 Emerin oligomerization and nucleoskeletal coupling at the nuclear envelope regulate nuclear mechanics against stress

Fernandez, A. M.; Bautista, M.; Pinaud, F.

10.1101/2021.02.12.429834 — cell biology — Posted on 2021-03-07

3887 Scarcity of hosts for gregarious parasitoids indicates an increase of individual offspring fertility by reducing their own fertility

Samkova, A.; Raska, J.; Hadrava, J.; Skuhrovec, J.

10.1101/2021.03.05.434037 — zoology — Posted on 2021-03-07

3888 Data-driven learning how oncogenic gene expression locally alters heterocellular networks

Klinke, D. J.; Fernandez, A.; Deng, W.; Latifizadeh, H.; Pirkey, A. C.

10.1101/2020.05.04.077107 — systems biology — Posted on 2021-03-07

3889 BoolSim, a Graphical Interface for Open Access Boolean Network Simulations and Use in Guard Cell CO2 Signaling

Karanam, A. R.; He, D.; Hsu, P.-K.; Schulze, S.; Dubeaux, G.; Karmakar, R.; Schroeder, J.; Rappel, W.-J.

10.1101/2021.03.05.434139 — plant biology — Posted on 2021-03-07

3890 Conserved, divergent and heterochronic gene expression during Brachypodium and Arabidopsis embryo development

Hao, Z.; Zhang, Z.; Xiang, D.; Venglat, P.; Chen, J.; Gao, P.; Datla, R.; Weijers, D.

10.1101/2021.03.05.434107 — plant biology — Posted on 2021-03-07

3891 The lncRNA APOLO interacts with the transcription factor WRKY42 to trigger root hair cell expansion in response to cold

Moison, M.; Martinez Pacheco, J.; Lucero, L.; Fonouni-Farde, C.; Rodriguez-Melo, J.; Mansilla, N.; Christ, A.; Bazin, J.; Benhamed, M.; Ibanez, F.; Crespi, M.; Estevez, J.; Ariel, F.

10.1101/2020.07.13.188763 — plant biology — Posted on 2021-03-07

3892 Transcriptional census of epithelial-mesenchymal plasticity in cancer

Cook, D. P.; Vanderhyden, B. C.

10.1101/2021.03.05.434142 — cancer biology — Posted on 2021-03-07

3893 Placenta DNA methylation at ZNF300 is associated with fetal sex and placental morphology

10.1101/2021.03.05.433992 — genomics — Posted on 2021-03-07

3894 Genomic Prediction In An Outcrossing Autotetraploid Fruit Crop: Lessons From Blueberry Breeding

Ferrao, L. F. V.; Amadeu, R. R.; Benevenuto, J.; Oliveira, I. d. B.; Munoz, P. R.

10.1101/2021.03.05.434007 — genomics — Posted on 2021-03-07

3895 Multi-Modality Machine Learning Predicting Parkinsons Disease

Makarious, M. B.; Leonard, H. L.; Vitale, D.; Iwaki, H.; Sargent, L.; Dadu, A.; Violich, I.; Hutchins, E.; Saffo, D.; Bandres-Ciga, S.; Kim, J. J.; Song, Y.; Bookman, M.; Nojopranoto, W.; Campbell, R. H.; Hashemi, S. H.; Botia, J. A.; Carter, J. F.; Maleknia, M.; Craig, D. W.; Keuren-Jensen, K. V.; Morris, H. R.; Hardy, J. A.; Blauwendraat, C.; Singleton, A. B.; Faghri, F.; Nalls, M. A.; Accelerating Medicines Program - Parkinsons Disease (AMP PD), ; Global Parkinsons Genetics Program (GP2),

10.1101/2021.03.05.434104 — genomics — Posted on 2021-03-07

3896 Transcriptional-Regulatory Convergence Across Functional MDD Risk Variants Identified by Massively Parallel Reporter Assays

Mulvey, B.; Dougherty, J. D.

10.1101/2021.03.05.434177 — genetics — Posted on 2021-03-07

3897 Nano-CT characterization reveals coordinated growth of a rudimentary organ necessary for soldier development in the ant Pheidole hyatti

Koch, S.; Tahara, R.; Vasquez Correa, A.; Abouheif, E.

10.1101/2021.03.05.434146 — developmental biology — Posted on 2021-03-07

3898 Chromatin accessibility and microRNA expression in nephron progenitor cells during kidney development

Clugston, A.; Bodnar, A.; Cerqueira, D.; Pua, Y. L.; Lawler, A.; Boggs, K.; Pfenning, A.; Ho, J.; Kostka, D.

10.1101/2021.03.05.434138 — developmental biology — Posted on 2021-03-07

3899 Mechanism of REST/NRSF Regulation of Clustered Protocadherin Alpha Genes

Tang, Y.; Jia, Z.; Xu, H.; Da, L.-T.; Wu, Q.

10.1101/2021.03.06.434230 — molecular biology — Posted on 2021-03-07

3900 Invasive Earthworms Alter Forest Soil Microbiomes and Nitrogen Cycling

Jang, J.; Xiong, X.; Liu, C.; Yoo, K.; Ishii, S.

10.1101/2021.03.07.433105 — microbiology — Posted on 2021-03-07

3901 TCRβ rearrangements without D-segment are common, abundant and public

de Greef, P. C.; de Boer, R. J.

10.1101/2021.03.05.434088 — immunology — Posted on 2021-03-07

3902 Interleukin-17A causes osteoarthritis-like transcriptional changes in human osteoarthritis-derived chondrocytes and synovial fibroblasts in vitro

Mimpen, J. Y.; Baldwin, M. J.; Cribbs, A. P.; Philpott, M.; Carr, A. J.; Dakin, S. G.; Snelling, S. J. B.

10.1101/2021.03.05.434099 — immunology — Posted on 2021-03-07

3903 Pathogenic tau disrupts the cellular program that maintains neuronal identity

Beckmann, A.; Ramirez, P.; Gamez, M.; Ray, W. J.; Frost, B.

10.1101/2021.03.05.434166 — neuroscience — Posted on 2021-03-07

3904 Differential impact of transdiagnostic, dimensional psychopathology on multiple scales of functional connectivity

Seok, D.; Beer, J.; Jaskir, M.; Smyk, N.; Jaganjac, A.; Makhoul, W.; Cook, P.; Elliott, M.; Shinohara, R.; Sheline, Y. I.

10.1101/2021.03.05.434151 — neuroscience — Posted on 2021-03-07

3905 Gait-phase modulates alpha and beta oscillations in the pedunculopontine nucleus

He, S.; Deli, A.; Fischer, P.; Wiest, C.; Huang, Y.; Martin, S.; Khawaldeh, S.; Aziz, T. Z.; Green, A. L.; Brown, P.; Tan, H.

10.1101/2021.03.05.434086 — neuroscience — Posted on 2021-03-07

3906 Inhibition of peripheral VEGF signaling rapidly reduces leucocyte obstructions in brain capillaries and increases cortical blood flow in an Alzheimers disease mouse model

Ali, M.; Njiru, B. N.; Falkenhain, K.; Murtaza-Ali, M.; Ruiz-Uribe, N. E.; Haft-Javaherian, M.; StallCatchers, ; Nishimura, N.; Schaffer, C. B.; Bracko, O.

10.1101/2021.03.05.433976 — neuroscience — Posted on 2021-03-07

3907 Revealing Spatiotemporal Circuit Information of Olfactory Bulb in Large-scale Neural Recordings

Hu, X.; Khanzada, S.; Kluetsch, D.; Calegari, F.; Amin, H.

10.1101/2021.03.05.434081 — neuroscience — Posted on 2021-03-07

3908 Neurodegeneration in human brain organoids infected with herpes simplex virus type 1

Rybak-Wolf, A.; Wyler, E.; Legnini, I.; Loewa, A.; Glazar, P.; Joon Kim, S.; Pentimalli, T. M.; Oliveras Martinez, A.; Beyersdorf, B.; Woehler, A.; Landthaler, M.; Rajewsky, N.

10.1101/2021.03.05.434122 — neuroscience — Posted on 2021-03-07

3909 Procollagen C-Proteinase Enhancer 1 (PCPE-1) is a marker of myocardial fibrosis and impaired cardiac function in a murine model of pressure overload

Lagoutte, P.; Oudot, A.; Dussoyer, M.; Goncalves, V.; Guillemin, M.; Bouchot, O.; Vandroux, D.; Bellaye, P.-S.; Moali, C.; Vadon-Le Goff, S.

10.1101/2021.03.05.434071 — physiology — Posted on 2021-03-07

3910 Intra-epithelial non-canonical Activin A signalling safeguards prostate progenitor quiescence

10.1101/2021.03.05.433921 — cancer biology — Posted on 2021-03-07

3911 Hepatic Leukemia Factor supports the propagation of leukemia and hematopoietic stem cell function during stress-induced regeneration.

Baudet, A.; Komorowska, K.; Hultmark, S.; Chapellier, M.; Miharada, K.; Larsson, J.; Bryder, D.; Jaras, M.; Juliusson, G.; Magnusson, M.

10.1101/2021.03.05.434034 — cancer biology — Posted on 2021-03-07

3912 A Patient-Specific Model of Transcatheter Valve Replacement in aBicuspid Heart Valve

McGee, O. M.; McNamara, A.; McNamara, L. M.

10.1101/2021.03.05.433633 — bioengineering — Posted on 2021-03-07

3913 αB-crystallin affects the morphology of Aβ(1-40) aggregates

Muller, H.; Dias, D. M.; van der Zalm, A.; Baldwin, A.

10.1101/2021.03.07.433908 — biochemistry — Posted on 2021-03-07

3914 Choice of alignment pipeline strongly influences clustering quality of scRNA-seq datasets

Shainer, I.; Stemmer, M.

10.1101/2021.03.05.434032 — genomics — Posted on 2021-03-07

3915 Proteogenomic characterization of hepatocellular carcinoma

Ng, C. K.; Dazert, E.; Boldanova, T.; Coto-Llerena, M.; Nuciforo, S.; Ercan, C.; Suslov, A.; Meier, M.-A.; Bock, T.; Schmidt, A.; Ketterer, S.; Wang, X.; Wieland, S.; Matter, M. S.; Colombi, M.; Piscuoglio, S.; Terracciano, L. M.; Hall, M. N.; Heim, M. H.

10.1101/2021.03.05.434147 — genomics — Posted on 2021-03-07

3916 Reduction of genotyping marker density for genomic selection is not an affordable approach to long-term breeding in cross-pollinated crops

DoVale, J. C.; Carvalho, H. F.; Sabadin, F.; Fritsche-Neto, R.

10.1101/2021.03.05.434084 — genetics — Posted on 2021-03-07

3917 Novel regulators of growth identified in the evolution of fin proportion in flying fish

Daane, J. M.; Blum, N.; Lanni, J.; Boldt, H.; Iovine, M. K.; Higdon, C. W.; Johnson, S. L.; Lovejoy, N. R.; Harris, M. P.

10.1101/2021.03.05.434157 — developmental biology — Posted on 2021-03-07

3918 Lung organoids and microplastic fibers: a new exposure model for emerging contaminants

Winkler, A. S.; Santo, N.; Madasci, L.; Cherubini, A.; Rusconi, F.; Rosso, L.; Tremolada, P.; Lazzari, L.; Bacchetta, R.

10.1101/2021.03.07.434247 — molecular biology — Posted on 2021-03-07

3919 Translational activation by an alternative sigma factor in Bacillus subtilis

McCormick, D. M.; Lalanne, J.-B.; Lan, T. C. T.; Rouskin, S.; Li, G.-W.

10.1101/2021.03.06.434181 — microbiology — Posted on 2021-03-07

3920 Computationally reconstructed interactome of Bradyrhizobium diazoefficiens USDA110 reveals novel functional modules and protein hubs for symbiotic nitrogen fixation

Ma, J.-X.; Yang, Y.; Li, G.; Ma, B.-G.

10.1101/2021.03.06.434201 — systems biology — Posted on 2021-03-07

3921 Impact of isolation method on cellular activation and presence of specific tendon cell subpopulations during in vitro culture

Nichols, A. E.; Miller, S. E.; Green, L. J.; Richards, M. S.; Loiselle, A. E.

10.1101/2021.03.07.434268 — cell biology — Posted on 2021-03-07

3922 Motor neuron boutons remodel through membrane blebbing

Fernandes, A. R.; Mendes, C. S.; Gomes, E. R.; Teodoro, R. O.

10.1101/2021.03.07.434250 — cell biology — Posted on 2021-03-07

3923 A Simple Fluorescence Assay for Cystine Uptake via the xCT in Cells using Selenocystine and a Fluorescent Probe

Shimomura, T.; Hirakawa, N.; Ohuchi, Y.; Ishiyama, M.; Shiga, M.; Ueno, Y.

10.1101/2021.03.05.434035 — cell biology — Posted on 2021-03-07

3924 Molecular basis for SPINDOC-Spindlin1 engagement and its role in transcriptional inhibition

Zhao, F.; Yang, F.; Feng, F.; Peng, B.; Bedford, M. T.; Li, H.

10.1101/2021.03.07.432812 — biophysics — Posted on 2021-03-07

3925 Multi-modal imaging reveals dynamic interactions of Staphylococcus aureus within human neutrophils

Ho, Y. X.; Steele, E.; Prince, L.; Cadby, A.

10.1101/2021.03.05.434126 — biophysics — Posted on 2021-03-07

3926 Substrate mediated elastic coupling between motile cells modulates inter-cell interactions and enhances cell-cell contact

Bose, S.; Dasbiswas, K.; Gopinath, A.

10.1101/2021.03.06.434234 — biophysics — Posted on 2021-03-07

3927 A specialized bone marrow microenvironment for fetal haematopoiesis

Liu, Y.; Chen, Q.; Jeong, H.-W.; Watson, E.; Xu, C.; Stehling, M.; Zhou, B.; Adams, R. H.

10.1101/2021.03.05.434039 — developmental biology — Posted on 2021-03-07

3928 Microtubule-based Transport is Essential to Distribute RNA and Nascent Protein in Skeletal Muscle

Denes, L. T.; Kelley, C. P.; Wang, E. T.

10.1101/2021.02.26.433059 — cell biology — Posted on 2021-03-07

3929 Pharmacological targeting of a PWWP domain demonstrates cooperative control of NSD2 localization

Dilworth, D.; Hanley, R. P.; Ferreira de Freitas, R.; Allali-Hassani, A.; Zhou, M.; Mehta, N.; Marunde, M. R.; Ackloo, S.; Marcon, E.; Li, F.; Chau, I.; Bolotokova, A.; Qin, S.; Lei, M.; Liu, Y.; Szewczyk, M.; Dong, A.; Kazemzadeh, S.; Abramyan, T.; Popova, I. K.; Hall, N. W.; Meiners, M. J.; Cheek, M. A.; Gibson, E.; Kireev, D.; Greenblatt, J.; Keogh, M.-C.; Min, J.; Brown, P. J.; Vedadi, M.; Arrowsmith, C. H.; Barsyte-Lovejoy, D.; James, L.; Schapira, M.

10.1101/2021.03.05.433782 — cell biology — Posted on 2021-03-07

3930 3D Cell Neighbour Dynamics in Growing Pseudostratified Epithelia

Gomez, H.; Dumond, M.; Hodel, L.; Vetter, R.; Iber, D.

10.1101/2021.03.05.434123 — cell biology — Posted on 2021-03-07

3931 Active Enterohepatic Cycling is Not Required for the Choleretic Actions of 24-norUrsodeoxycholic Acid in Mice

Li, J.; Truong, J. K.; Pachura, K.; Rao, A.; Gambeer, S.; Fuchs, C. D.; Karpen, S. J.; Trauner, M. J.; Dawson, P. A.

10.1101/2021.03.06.430841 — cell biology — Posted on 2021-03-07

3932 Mesenchymal Stromal Cell Aging Impairs the Self-Organizing Capacity of Lung Alveolar Epithelial Stem Cells

Chanda, D.; Rehan, M.; Smith, S. R.; Dsouza, K. G.; Wang, Y.; Bernard, K.; Kurundkar, D.; Memula, V.; Kojima, K.; Mobley, J. A.; Benavides, G.; Darley-Usmar, V.; Kim, Y.-i.; Zmijewski, J. W.; Deshane, J.; Thannickal, V. J.

10.1101/2021.03.05.434121 — cell biology — Posted on 2021-03-07

3933 An extracellular redox signal triggers calcium release and impacts the asexual development of Toxoplasma gondii

Alves, E.; Benns, H. J.; Magnus, L.; Dominicus, C.; Dobai, T.; Blight, J.; Wincott, C. J.; Child, M. A.

10.1101/2021.02.04.429728 — microbiology — Posted on 2021-03-07

3934 Control of aperture closure during reach-to-grasp movements in immersive haptic-free virtual reality

Mangalam, M.; Yarossi, M.; Furmanek, M. P.; Tunik, E.

10.1101/2020.08.01.232470 — neuroscience — Posted on 2021-03-07

3935 Spike-timing-dependent plasticity can account for aftereffects of dual-site transcranial alternating current stimulation

Schwab, B. C.; König, P.; Engel, A. K.

10.1101/2020.10.16.342105 — neuroscience — Posted on 2021-03-07

3936 Dual RNA modulation of protein mobility and stability within phase-separated condensates

Tejedor, A. R.; Garaizar, A.; Ramirez, J.; Espinosa, J. R.

10.1101/2021.03.05.434111 — biophysics — Posted on 2021-03-07

3937 Razor: annotation of signal peptides from toxins

Bhandari, B. K.; Gardner, P. P.; Lim, C. S.

10.1101/2020.11.30.405613 — bioinformatics — Posted on 2021-03-07

3938 Collective behavior emerges from genetically controlled simple behavioral motifs in zebrafish

Aspiras, A. C.; Harpaz, R.; Chambule, S.; Tseng, S.; Engert, F.; Fishman, M. C.; Bahl, A.

10.1101/2021.03.03.433803 — animal behavior and cognition — Posted on 2021-03-07

3939 AGES: An auxin-inducible, GAL4-compatible, gene expression system for Drosophila

McClure, C. D.; Hassan, A.; Duggal, A.; Ying Sia, C.; Southall, T. D.

10.1101/2021.01.26.428209 — genetics — Posted on 2021-03-07

3940 Brainprints: identifying individuals from magnetoencephalograms

Wu, S.; Ramdas, A.; Wehbe, L.

10.1101/2020.06.18.159913 — neuroscience — Posted on 2021-03-07

3941 CA1 pyramidal cell diversity is rooted in the time of neurogenesis.

Cavalieri, D.; Angelova, A.; Islah, A.; Lopez, C.; Baude, A.; Cossart, R.

10.1101/2021.03.07.433031 — neuroscience — Posted on 2021-03-07

3942 Parasitism and host dispersal plasticity in an aquatic model system

Zilio, G.; Noergaard, L. S.; Petrucci, G.; Zeballos, N.; Gougat-Barbera, C.; Fronhofer, E. A.; Kaltz, O.

10.1101/2020.07.30.228742 — evolutionary biology — Posted on 2021-03-07

3943 Comparative proximity biotinylation implicates RAB18 in cholesterol mobilization and biosynthesis

Kiss, R. S.; Chicoine, J.; Khalil, Y.; Sladek, R.; Chen, H.; Pisaturo, A.; Martin, C.; Dale, J. D.; Brudenell, T. A.; Kamath, A.; Paci, E.; Clayton, P.; Wills, J. C.; von Kriegsheim, A.; Nilsson, T.; Sheridan, E.; Handley, M. T.

10.1101/871517 — cell biology — Posted on 2021-03-07

3944 Laboratory evolution of anticipatory gene regulation in Escherichia coli.

Mahilkar, A.; Mall, A.; Saini, S.

10.1101/2020.08.20.259606 — microbiology — Posted on 2021-03-07

3945 A novel two-generation approach to the population dynamics of gregarious parasitoids

Samkova, A.; Raska, J.; Hadrava, J.; Skuhrovec, J.

10.1101/2021.02.22.432341 — zoology — Posted on 2021-03-07

3946 Large scale genomic rearrangements in selected Arabidopsis thaliana T-DNA lines are caused by T-DNA insertion mutagenesis

Pucker, B.; Kleinboelting, N.; Weisshaar, B.

10.1101/2021.03.03.433755 — plant biology — Posted on 2021-03-07

3947 Complementary Phenotyping of Maize Root Architecture by Root Pulling Force and X-Ray Computed Tomography

Shao, M.-R.; Jiang, N.; Li, M.; Howard, A.; Lehner, K.; Mullen, J. L.; Gunn, S. L.; McKay, J.; Topp, C. N.

10.1101/2021.03.03.433776 — plant biology — Posted on 2021-03-07

3948 Periodicity in the embryo: emergence of order in space, diffusion of order in time

Alicea, B. J.; Parent, J.; Singh, U.; DevoWorm Group,

10.1101/2021.01.06.425581 — bioinformatics — Posted on 2021-03-07

3949 H3 acetylation selectively promotes basal progenitor proliferation and neocortex expansion by activating TRNP1 expression

Kerimoglu, C.; Pham, L.; Tonchev, A.; Sakib, M. S.; Xie, Y.; Sokpor, G.; Ulmke, P. A.; Kaurani, L.; Abbas, E.; Nguyen, H.; Rosenbusch, J.; Michurina, A.; Capece, V.; Angelova, M.; Esgleas, M.; Albert, M.; Minkov, R.; Kovachev, E.; Teichmann, U.; Seong, R. H.; Huttner, W.; Goetz, M.; Nguyen, H. P.; Stoykova, A.; Staiger, J. F.; Fischer, A.; Tuoc, T.

10.1101/2021.03.06.434209 — developmental biology — Posted on 2021-03-06

3950 Brazil Nut Effect Drives Pattern Formation in Early Mammalian Embryos

guo, z.; Yao, J.; Zheng, X.; Cao, J.; Gao, Z.; Guo, S.; Qin, D.; Tan, M.; Wang, B.; Meng, F.; Zhang, J.; Li, L.; Du, J.; Fan, Y.

10.1101/2021.02.26.433068 — developmental biology — Posted on 2021-03-07

3951 Eliminating Mosquitoes with Precision Guided Sterile Males

Li, M.; Yang, T.; Bui, M.; Gamez, S.; Wise, T.; Kandul, N. P.; Liu, J.; Alcantara, L.; Lee, H.; Edula, J. R.; Raban, R.; Zhan, Y.; Wang, Y.; DeBeaubien, N.; Chan, J.; Sanchez, H. M.; Bennett, J. B.; Antoshechkin, I.; Montell, C.; Marshall, J. M.; Akbari, O. S.

10.1101/2021.03.05.434167 — genetics — Posted on 2021-03-06

3952 Trp53 ablation fails to prevent microcephaly in mouse pallium with impaired minor intron splicing

White, A. K.; Baumgartner, M.; Lee, M. F.; Drake, K. D.; Aquino, G. S.; Kanadia, R.

10.1101/2021.03.05.434172 — developmental biology — Posted on 2021-03-06

3953 The evolution of mechanisms to divide labour in microorganisms

Cooper, G. A.; Liu, M.; Peña, J.; West, S. A.

10.1101/2020.02.25.964643 — evolutionary biology — Posted on 2021-03-06

3954 Fibroblast activation protein regulates natural killer cell migration, extravasation and tumor infiltration

Fitzgerald, A. A.; Marcisak, E. F.; Nasir, A.; Glasgow, E.; Jablonski, S.; Van der Veken, P.; Pearson, G.; Fertig, E. J.; Mace, E. M.; Weiner, L. M.

10.1101/2021.02.03.429622 — immunology — Posted on 2021-03-06

3955 Large-scale societal dynamics are reflected in human mood and brain

Lebedev, A. V.; Abe, C.; Acar, K.; Deco, G.; Kringelbach, M. L.; Ingvar, M.; Petrovic, P.

10.1101/2020.10.07.329201 — neuroscience — Posted on 2021-03-06

3956 Modeling features of addiction with an oral oxycodone self-administration paradigm

Murphy, C.; Chang, Y.-H.; Pareta, R.; Li, J.-N.; Earnest, T.; Tooley, J. R.; Abiraman, K.; Vachez, Y. M.; Gereau, R.; Copits, B. A.; Kravitz, A. V.; Creed, M. C.

10.1101/2021.02.08.430180 — neuroscience — Posted on 2021-03-06

3957 CXCR4 allows T cell acute lymphoblastic leukemia to escape from JAK1/2 and BCL2 inhibition through CNS infiltration

Walker, K. L.; Rinella, S. P.; Hess, N. J.; Turicek, D. P.; Kabakov, S. A.; Zhu, F.; Bouchlaka, M. N.; Olson, S. L.; Cho, M. M.; Quamine, A. E.; Feils, A. S.; Gavcovich, T. B.; Rui, L.; Capitini, C. M.

10.1101/734913 — cancer biology — Posted on 2021-03-06

3958 Molecular phenotyping of breast cancer cell lines at the single-cell level for automated cancer diagnosis and prediction of drug sensitivity

Gambardella, G.; Viscido, G.; Tumaini, B.; Isacchi, A.; Bosotti, R.; di Bernardo, D.

10.1101/2021.03.02.433590 — cancer biology — Posted on 2021-03-06

3959 Inference of deformation mechanisms and constitutive response of soft material surrogates of biological tissue by full-field characterization and data-driven variational system identification

Wang, Z.; Estrada, J. B.; Arruda, E. M.; Garikipati, K.

10.1101/2020.10.13.337964 — biophysics — Posted on 2021-03-06

3960 Genome-wide characterization of human minisatellite VNTRs: population-specific alleles and gene expression differences

Eslami Rasekh, M.; Hernandez, Y.; Drinan, S. D.; Fuxman Bass, J. I.; Benson, G.

10.1101/2020.11.03.367367 — bioinformatics — Posted on 2021-03-06

3961 Human-in-the-Loop Weight Compensation in Upper Limb Wearable Robots Towards Total Muscles Effort Minimization

Nasiri, R.; Aftabi, H.; Ahmadabadi, M. N.

10.1101/2020.11.02.366070 — bioengineering — Posted on 2021-03-06

3962 Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis

Pizzo, L.; Lasser, M.; Yusuff, T.; Jensen, M.; Ingraham, P.; Huber, E.; Singh, M. D.; Monahan, C.; Iyer, J.; Desai, I.; Karthikeyan, S.; Gould, D. J.; Yennawar, S.; Weiner, A. T.; Pouraja, V. K.; Krishnan, A.; Rolls, M.; Lowery, L. A.; Girirajan, S.

10.1101/2020.09.14.295923 — genomics — Posted on 2021-03-06

3963 An inverse modelling study on the local volume changes during early growth of the fetal human brain

Wang, Z.; Martin, B.; Weickenmeier, J.; Garikipati, K.

10.1101/2020.10.08.332411 — developmental biology — Posted on 2021-03-06

3964 Metacognitive awareness of difficulty in action selection: the role of the cingulo-opercular network

Desender, K.; Teuchies, M.; Gonzalez Garcia, C.; De Baene, W.; Demanet, J.; Brass, M.

10.1101/641340 — neuroscience — Posted on 2021-03-06

3965 Memory precision of object-location binding is unimpaired in APOE ε4-carriers with spatial navigation deficits

Gellersen, H. M.; Coughlan, G.; Hornberger, M.; Simons, J. S.

10.1101/2020.12.18.423245 — neuroscience — Posted on 2021-03-06

3966 Data-driven learning how oncogenic gene expression locally alters heterocellular networks

Klinke, D. J.; Fernandez, A.; Deng, W.; Latifizadeh, H.; Pirkey, A. C.

10.1101/2020.05.04.077107 — systems biology — Posted on 2021-03-06

3967 Genomic structure and diversity of oak populations in British Parklands

Nocchi, G.; Brown, N.; Coker, T.; Plumb, W.; Stocks, J.; Denman, S.; Buggs, R. J. A.

10.1101/2021.03.05.434114 — genomics — Posted on 2021-03-06

3968 General and cell-type-specific aspects of the motor neuron maturation transcriptional program

Patel, T.; Hammelman, J.; Closser, M.; Gifford, D. K.; Wichterle, H.

10.1101/2021.03.05.434185 — developmental biology — Posted on 2021-03-06

3969 Host protease activity on bacterial pathogens promotes complement- and antibiotic-directed killing

Chen, S.; Roberts, A.-J.; Lu, F.; Southerland, M. R.; Cannon, C.; Qin, Q.-M.; de Figueiredo, P.

10.1101/2021.03.05.434144 — microbiology — Posted on 2021-03-06

3970 Benzofuran sulfonates and small self-lipid antigens activate type II NKT cells via CD1d

Almeida, C. F.; Smith, D.; Cheng, T.-Y.; Harpur, C.; Batleska, E.; Nguyen, T.; Hilmenyuk, T.; Nguyen-Robertson, C. V.; Reddiex, S. J.; Van Rhijn, I.; Rossjohn, J.; Uldrich, A. P.; Moody, B.; Williams, S. J.; Pellicci, D. G.; Godfrey, D. I.

10.1101/2021.03.05.433980 — immunology — Posted on 2021-03-06

3971 A Biosensor for Detection of Indole Metabolites

Wang, J.; Zhang, C.; Childers, W. S.

10.1101/2021.03.05.434140 — synthetic biology — Posted on 2021-03-06

3972 Nrf2 Regulates β-cell Mass by Suppressing Cell Death and Promoting Proliferation

Baumel-Alterzon, S.; Katz, L. S.; Brill, G.; Jean-Pierre, C.; Li, Y.; Biswal, S.; Garcia-Ocana, A.; Scott, D. K.

10.1101/2021.03.05.434145 — physiology — Posted on 2021-03-06

3973 Preferential allelic expression of PIK3CA mutations is frequent in breast cancer and is prognostically significant

Correia, L. W.; Xavier, J. M.; Magno, R.; de Almeida, B. P.; Esteves, F.; Duarte, I.; Eldridge, M.; Sun, C.; Bosma, A.; Mittempergher, L.; Marreiros, A.; Bernards, R.; Caldas, C.; Chin, S.-F.; Maia, A.-T.

10.1101/2021.03.05.434137 — cancer biology — Posted on 2021-03-06

3974 Dual RNA modulation of protein mobility and stability within phase-separated condensates

Tejedor, A. R.; Garaizar, A.; Ramirez, J.; Espinosa, J. R.

10.1101/2021.03.05.434111 — biophysics — Posted on 2021-03-06

3975 Eliminating Mosquitoes with Precision Guided Sterile Males

Akbari, O.; Li, M.; Yang, T.; Bui, M.; Gamez, S.; Wise, T.; Kandul, N. P.; Liu, J.; Alcantara, L.; Lee, H.; Edula, J. R.; Raban, R.; Zhan, Y.; Wang, Y.; DeBeaubien, N.; Chan, J.; Sanchez, H. M.; Bennett, J. B.; Antoshechkin, I.; Montell, C.; Marshall, J. M.

10.1101/2021.03.05.434167 — genetics — Posted on 2021-03-06

3976 Recombinant haplotypes reflect sexual reproduction in symbiotic arbuscular mycorrhizal fungi

Mateus, I. D.; Auxier, B.; Ndiaye, M. M. S.; Cruz, J.; Lee, S.-J.; Sanders, I. R.

10.1101/2021.03.05.434083 — evolutionary biology — Posted on 2021-03-06

3977 Engineered Peptide-Functionalized Hydrogels Modulate the RNA Transcriptome of Human Nucleus Pulposus Cells In Vitro

Barcellona, M. N.; Speer, J. E.; Jing, L.; Gupta, M. C.; Buchowski, J. M.; Kelly, M. P.; Setton, L. A.

10.1101/2021.03.05.434094 — cell biology — Posted on 2021-03-06

3978 A genetically encoded fluorescent biosensor for extracellular L-lactate

NASU, Y.; Murphy-Royal, C.; Wen, Y.; Haidey, J.; Molina, R. S.; Aggarwal, A.; Zhang, S.; Kamijo, Y.; Paquet, M.-E.; Podgorski, K.; Drobizhev, M.; Bains, J. S.; Lemieux, M. J.; Gordon, G. R.; Campbell, R. E.

10.1101/2021.03.05.434048 — molecular biology — Posted on 2021-03-06

3979 Defining proximity proteomics of post-translationally modified proteins by antibody-mediated protein A-APEX2 labeling

Li, X.; Zhou, J.; Zhao, W.; Wen, Q.; Wang, W.; Peng, H.; Bouchonville, K. J.; Offer, S. M.; Wang, Z.; Li, N.; Gan, H.

10.1101/2021.03.05.434178 — molecular biology — Posted on 2021-03-06

3980 Dysbiotic oral and gut viromes in untreated and treated rheumatoid arthritis patients

Guo, R.; Li, S.; Zhang, Y.; Zhang, Y.; Wang, G.; Ma, Y.; Yan, Q.

10.1101/2021.03.05.434018 — microbiology — Posted on 2021-03-06

3981 Critical Assessment of Metaproteome Investigation (CAMPI): a Multi-Lab Comparison of Established Workflows

Van Den Bossche, T.; Kunath, B. J.; Schallert, K.; Schäpe, S. S.; Abraham, P. E.; Armengaud, J.; Arntzen, M. O.; Bassignani, A.; Benndorf, D.; Fuchs, S.; Giannone, R. J.; Griffin, T. J.; Hagen, L. H.; Halder, R.; Henry, C.; Hettich, R. L.; Heyer, R.; Jagtap, P.; Jehmlich, N.; Jensen, M.; Juste, C.; Kleiner, M.; Langella, O.; Lehmann, T.; Leith, E.; May, P.; Mesuere, B.; Miotello, G.; Peters, S. L.; Pible, O.; Reichl, U.; Renard, B. Y.; Schiebenhoefer, H.; Scryba, A.; Tanca, A.; Trappe, K.; Trezzi, J.-P.; Uzzau, S.; Verschaffelt, P.; von Bergen, M.; Wilmes, P.; Wolf, M.; Martens, L.; Muth, T.

10.1101/2021.03.05.433915 — microbiology — Posted on 2021-03-06

3982 The Mycobacterium tuberculosis transposon sequencing database (MtbTnDB): a large-scale guide to genetic conditional essentiality

Jinich, A.; Zaveri, A.; DeJesus, M. A.; Flores-Bautista, E.; Smith, C. M.; Sassetti, C. M.; Rock, J. M.; Ehrt, S.; Schnappinger, D.; Ioerger, T. R.; Rhee, K. Y.

10.1101/2021.03.05.434127 — microbiology — Posted on 2021-03-06

3983 Mycobacterium abscessus biofilms produce an ECM and have a distinct mycolic acid profile

Dokic, A.; Peterson, E.; Arrieta-Ortiz, M.; Pan, M.; Di Maio, A.; Baliga, N.; Bhatt, A.

10.1101/2021.03.05.434154 — microbiology — Posted on 2021-03-06

3984 Fungal taste for minerals: the ectomycorrhizal fungus Paxillus involutus triggers specific genes when extracting potassium from different silicates

Pinzari, F.; Jungblut, A. D.; Cuadros, J.

10.1101/2021.03.05.434133 — microbiology — Posted on 2021-03-06

3985 Binding of the Andes Virus Nucleocapsid Protein to RhoGDI Induces the Release and Activation of the Permeability Factor RhoA

Gorbunova, E. E.; Mackow, E. R.

10.1101/2021.03.05.434186 — microbiology — Posted on 2021-03-06

3986 Diversification of B. subtilis during experimental evolution on A. thaliana leads to synergism in root colonization of evolved subpopulations

Blake, C.; Nordgaard Christensen, M.; Maroti, G.; Kovacs, A. T.

10.1101/2021.03.06.434191 — microbiology — Posted on 2021-03-06

3987 Anaerobic microbiota facilitate P. aeruginosa access to airway epithelia in a novel co-culture model of colonization

Moore, P. J.; Wiggen, T. D.; Kent, L. A.; Arif, S. J.; Lucas, S. K.; O'Grady, S. M.; Hunter, R. C.

10.1101/2021.03.05.433759 — microbiology — Posted on 2021-03-06

3988 Exploration of polyyne biosynthetic gene cluster diversity in bacteria leads to the discovery of the Pseudomonas polyyne protegencin

Mullins, A. J.; Webster, G.; Kim, H. J.; Zhao, J.; Petrova, Y. D.; Ramming, C. E.; Jenner, M.; Murray, J. A. H.; Connor, T. R.; Hertweck, C.; Challis, G. L.; Mahenthiralingam, E.

10.1101/2021.03.05.433886 — microbiology — Posted on 2021-03-06

3989 Multiple classes of bactericidal antibiotics cause DNA double strand breaks in Staphylococcus aureus

Clarke, R. S.; Edwards, A. M.

10.1101/2021.03.05.434095 — microbiology — Posted on 2021-03-06

3990 Biochemical reconstitution defines new functions for membrane-bound glycosidases in assembly of the bacterial cell wall

Taguchi, A.; Walker, S.

10.1101/2021.03.06.434200 — microbiology — Posted on 2021-03-06

3991 An Investigation of the Mechanism for a Novel Influenza Inhibitor Designed to Target the Import of PB1

Dorius, D. A.; Busath, D. D.

10.1101/2021.03.05.434155 — microbiology — Posted on 2021-03-06

3992 Multiplexed VaxArray Immunoassay for Rapid Antigen Quantification in Measles and Rubella Vaccine Manufacturing

Gillis, J. H.; Thomas, K. N.; Manoharan, S.; Panchakshari, M.; Taylor, A. W.; Miller, D. F.; Byrne-Nash, R. T.; Riley, C.; Rowlen, K. L.; Dawson, E. D.

10.1101/2021.03.05.433809 — immunology — Posted on 2021-03-06

3993 Protein-bound sialic acid in saliva contributes directly to salivary anti-influenza virus activity

Kobayashi, K.; Shono, C.; Mori, T.; Kitazawa, H.; Noriyasu, O.; Kurebayashi, Y.; Suzuki, T.

10.1101/2021.03.05.433813 — immunology — Posted on 2021-03-06

3994 Feedback ratiometric control of two microbial populations in a single chemostat

Fiore, D.; Della Rossa, F.; Guarino, A.; di Bernardo, M.

10.1101/2021.03.05.434159 — synthetic biology — Posted on 2021-03-06

3995 A non-coding RNA network involved in KSHV tumorigenesis

Naipauer, J.; Garcia Sola, M. E.; Salyakina, D.; Rosario, S.; Williams, S.; Coso, O.; Abba, M. C.; Mesri, E. A.; Lacunza, E.

10.1101/2021.03.05.434134 — cancer biology — Posted on 2021-03-06

3996 HOXA9 acts as a regulatory switch in acute myeloid leukaemia and myeloproliferative neoplasms

Talarmain, L.; Clarke, M. A.; Fisher, J.; Hall, B. A.

10.1101/2021.03.05.434116 — cancer biology — Posted on 2021-03-06

3997 Tissue specific targeting of DNA nanodevices in a multicellular living organism

Krishnan, Y.; Chakraborty, K.; Surana, S.; Martin, S.; Aburas, J.; Moutel, S.; Perez, F.; Koushika, S. P.; Kratsios, P.

10.1101/2021.03.05.434169 — biochemistry — Posted on 2021-03-06

3998 Cell competition removes segmental aneuploid cells from Drosophila imaginal disc-derived tissues based on ribosomal protein gene dose

ji, z.; Chuen, J.; Kiparaki, M.; baker, n. e.

10.1101/2021.03.05.433802 — genetics — Posted on 2021-03-06

3999 A novel Rab11-Rab3a cascade required for lysosome exocytosis

Escrevente, C.; Lopes, L. B.; Ramalho, J.; Barral, D. C.

10.1101/2021.03.06.434066 — cell biology — Posted on 2021-03-06

4000 SARS-CoV-2 501Y.V2 (B.1.351) elicits cross-reactive neutralizing antibodies

Moyo-Gwete, T.; Madzivhandila, M.; Makhado, Z.; Ayres, F.; Mhlanga, D.; Oosthuysen, B.; Lambson, B.; Kgagudi, P.; Tegally, H.; Iranzadeh, A.; Doolabh, D.; Tyers, L.; Chinhoyi, L.; Mennen, M.; Skelem, S.; Wibmer, C. K.; Bhiman, J.; Ueckermann, V.; Rossouw, T.; Boswell, M.; de Oliveira, T.; Williamson, C.; Burgers, W.; Ntusi, N.; Morris, L.; Moore, P.

10.1101/2021.03.06.434193 — immunology — Posted on 2021-03-06

4001 Resolving the Dynamic Motions of SARS-CoV-2 nsp7 and nsp8 Proteins Using Structural Proteomics

Courouble, V.; Dey, S.; Yadav, R.; Timm, J.; Harrison, J.; Ruiz, F. X.; Arnold, E.; Griffin, P. R.

10.1101/2021.03.06.434214 — biophysics — Posted on 2021-03-06

4002 Long-read sequencing of SARS-CoV-2 reveals novel transcripts and a diverse complex transcriptome landscape.

Li-Pook-Than, J.; Banuelos, S.; Honkala, A.; Sahoo, M. K.; Pinsky, B. A.; Snyder, M. P.

10.1101/2021.03.05.434150 — genetics — Posted on 2021-03-06

4003 Evolution of VIM-1 producing Klebsiella pneumoniae isolates from a hospital outbreak reveals the genetic bases of the loss of the urease-positive identification character

Cabanel, N.; Rosinski-Chupin, I.; Chiarelli, A.; Botin, T.; Tato, M.; Canton, R.; Glaser, P.

10.1101/2021.03.02.433680 — evolutionary biology — Posted on 2021-03-06

4004 SARS-CoV-2 surveillance in Norway rats (Rattus norvergicus) from Antwerp sewer system, Belgium

Colombo, V. C.; Sluydts, V.; Marien, J.; Vanden Broecke, B.; Van Houtte, N.; Leirs, W.; Jacobs, L.; Iserbyt, A.; Hubert, M.; Heyndrickx, L.; Goris, H.; Delputte, P.; De Roeck, N.; Elst, J.; Boudewijns, R.; Arien, K.; Leirs, H.; Gryseels, S.

10.1101/2021.03.06.433708 — ecology — Posted on 2021-03-06

4005 The cryptic gonadotropin-releasing hormone neuronal system of human basal ganglia

Skrapits, K.; Sarvari, M.; Farkas, I.; Göcz, B.; Takacs, S.; Rumpler, E.; Vaczi, V.; Vastagh, C.; Racz, G.; Matolcsy, A.; Solymosi, N.; Poliska, S.; Toth, B.; Erdelyi, F.; Szabo, G.; Culler, M. D.; Allet, C.; Cotellessa, L.; Prevot, V.; Giacobini, P.; Hrabovszky, E.

10.1101/2021.03.04.433872 — cell biology — Posted on 2021-03-06

4006 Arc rescues defective synaptic plasticity and cognitive dysfunction in sepsis-associated encephalopathy

10.1101/2021.03.04.433352 — neuroscience — Posted on 2021-03-06

4007 Complementary task representationsin hippocampus and prefrontal cortexfor generalising the structure of problems

Samborska, V.; Butler, J. L.; Walton, M. E.; Behrens, T. E. J.; Akam, T.

10.1101/2021.03.05.433967 — neuroscience — Posted on 2021-03-06

4008 The pH-dependent processivity of Arabidopsis AtPME2 can control cell wall mechanical properties

Hocq, L.; Harbrylo, O.; Voxeur, A.; Pau-Roblot, C.; Safran, J.; Senechal, F.; Fournet, F.; Bassard, S.; Battu, V.; Demailly, H.; Tovar, J. C.; Pilard, S.; Marcelo, P.; Savary, B.; Mercadante, D.; Njo, M.; Beeckman, T.; Boudaoud, A.; Pelloux, J.; Lefebvre, V.

10.1101/2021.03.03.433777 — plant biology — Posted on 2021-03-06

4009 Auxin-triggered changes in the Arabidopsis root tip (phospho)proteome reveal novel root growth regulators

De Smet, I.; Nikonorova, N.; Murphy, E.; Fonseca de Lima, C. F.; Zhu, S.; van de Cotte, B.; Vu, L. D.; Balcerowicz, D.; Li, L.; Kong, X.; De Rop, G.; Beeckman, T.; Friml, J.; Vissenberg, K.; Morris, P. C.; Ding, Z.

10.1101/2021.03.04.433936 — plant biology — Posted on 2021-03-06

4010 Lack of Tgfbr1 and Acvr1b synergistically stimulates myofibre hypertrophy and accelerates muscle regeneration

Hillege, M.; Shi, A.; Galli Caro, R.; Wu, G.; Bertolino, P.; Hoogaars, W. M.; Jaspers, R. T.

10.1101/2021.03.03.433740 — physiology — Posted on 2021-03-06

4011 EZH2 Abundance Regulated by UHRF1/UBE2L6/UBR4 Ubiquitin System is the Potential Therapeutic Target to Trigger Pigmented Phenotype in Melanoma

Kuser Abali, G.; Zhang, Y.; Szeto, P.; Zhao, P.; Masoumi Moghaddam, S.; Leece, I.; Huang, C.; Cheung, J.; Ameratunga, M.; Noguchi, F.; Andrews, M.; Wong, N. C.; Schittenhelm, R. B.; Shackleton, M.

10.1101/2021.03.04.433988 — cancer biology — Posted on 2021-03-06

4012 FEATURE DETECTION TO SEGMENT CARDIOMYOCYTE NUCLEI FOR INVESTIGATING CARDIAC CONTRACTILITY

Teranikar, T.; Villarreal, C.; Salehin, N.; Lim, J.; Ijaseun, T.; Cao, H.; Chuong, C.-J.; Lee, J.

10.1101/2021.03.03.433810 — bioengineering — Posted on 2021-03-06

4013 Transparent exploration of machine learning for biomarker discovery from proteomics and omics data

Strauss, M. T.; Torun, F. M.; Virreira Winter, S.; Doll, S.; Riese, F. M.; Vorobyev, A.; Müller-Reif, J. B.; Geyer, P. E.

10.1101/2021.03.05.434053 — biochemistry — Posted on 2021-03-06

4014 The human FLT1 regulatory element directs vascular expression and modulates angiogenesis pathways in vitro and in vivo

Stolper, J.; Voges, H. K.; See, M.; Rahmani Mehdiabadi, N.; Chahal, G.; Drvodelic, M.; Eichenlaub, M.; Labonne, T.; Schultz, B. G.; Hidalgo, A.; Centanin, L.; Wittbrodt, J.; Porrello, E. R.; Elliott, D. A.; Ramialison, M.

10.1101/2021.03.03.433738 — genomics — Posted on 2021-03-06

4015 CFAP61 is required for sperm flagellum formation and male fertility in human and mouse

Liu, S.; Zhang, J.; Kherraf, Z. E.; Sun, S.; Zhang, X.; Cazin, C.; Coutton, C.; Zouari, R.; Zhao, S.; Hu, F.; Mustapha, S. F. B.; Arnoult, C.; F. Ray, P.; Liu, M.

10.1101/2021.03.04.433881 — cell biology — Posted on 2021-03-06

4016 The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of Acute Myeloid Leukemias

Paolillo, R.; Boulanger, M.; Gatel, P.; Gabellier, L.; Tempe, D.; Hallal, R.; De Toledo, M.; Moreaux, J.; Baik, H.; Gueret, E.; Recher, C.; Sarry, J.-E.; Cartron, G.; Piechaczyk, M.; Bossis, G.

10.1101/2021.03.04.433871 — cancer biology — Posted on 2021-03-06

4017 Water levels affect photosynthesis and nutrient use more than salinity in a scrub Red Mangrove forest of the southeastern Florida Everglades

Hogan, J. A.; Castaneda-Moya, E.; Lamb-Wotton, L.; Troxler, T.; Baraloto, C.

10.1101/2021.01.27.428494 — plant biology — Posted on 2021-03-06

4018 A molecular phylogeny of forktail damselflies (genus Ischnura) reveals a dynamic macroevolutionary history of female colour polymorphisms

Blow, R.; Willink, B.; Svensson, E. I.

10.1101/2020.06.06.137828 — evolutionary biology — Posted on 2021-03-06

4019 A solution to temporal credit assignment using cell-type-specific modulatory signals

Liu, Y. H.; Smith, S. J.; Mihalas, S.; Shea-Brown, E.; Sumbul, U.

10.1101/2020.11.22.393504 — neuroscience — Posted on 2021-03-06

4020 Evaluating the efficacy of Optoα1AR activation in astrocytes in modulating basal hippocampal synaptic excitation and inhibition

Courtney, C. D.; Sobieski, C.; Ramakrishnan, C.; Ingram, R. J.; Wojnowski, N. M.; DeFazio, R. A.; Deisseroth, K.; Christian-Hinman, C. A.

10.1101/2021.01.06.425606 — neuroscience — Posted on 2021-03-06

4021 The Disease-Associated Proteins Drosophila Nab2 and Ataxin-2 Interact with Shared RNAs and Coregulate Neuronal Morphology

Rounds, J. C.; Corgiat, E. B.; Ye, C.; Behnke, J. A.; Kelly, S. M.; Corbett, A. H.; Moberg, K. H.

10.1101/2021.03.01.433469 — neuroscience — Posted on 2021-03-06

4022 Repetitive and Brief Occlusion of the Majority of the Vena Cava Flow Attenuates Pulmonary Arterial Hypertension and Improves IK+ of the Pulmonary Arterial Smooth Muscle Cells in Rat Models: a novel potential therapeutic strategy for PAH

Liu, N.; Xing, Y.; Wang, L.; Wang, C.

10.1101/2020.10.04.314708 — pathology — Posted on 2021-03-06

4023 Widespread misregulation of inter-species hybrid transcriptomes due to sex-specific and sex-chromosome regulatory evolution

Sanchez-Ramirez, S.; Weiss, J. G.; Thomas, C. G.; Cutter, A. D.

10.1101/2020.05.04.076505 — genomics — Posted on 2021-03-06

4024 Knockdown of Dnmt1 links Gene body DNA methylation to regulation of gene expression and maternal-zygotic transition in the wasp Nasonia

Arsala, D.; Wu, X.; Yi, S. V.; Lynch, J. A.

10.1101/2021.02.02.429402 — genomics — Posted on 2021-03-06

4025 Long runs of homozygosity are correlated with marriage preferences across global population samples

Sahoo, S. A.; Zaidi, A. A.; Anagol, S.; Mathieson, I.

10.1101/2021.03.04.433907 — genetics — Posted on 2021-03-06

4026 Distinguishing between recent balancing selection and incomplete sweep using deep neural networks

Isildak, U.; Stella, A.; Fumagalli, M.

10.1101/2020.07.31.230706 — evolutionary biology — Posted on 2021-03-06

4027 A Histoplasma capsulatum lipid metabolic map identifies antifungal targets and virulence factors

Zamith-Miranda, D.; Heyman, H. M.; Burnet, M. C.; Couvillion, S. P.; Zheng, X.; Munoz, N.; Nelson, W. C.; Kyle, J. E.; Zink, E. M.; Weitz, K. K.; Bloodsworth, K. J.; Clair, G. C.; Zucker, J. D.; Teuton, J. R.; Payne, S. H.; Kim, Y.-M.; Reyes Gil, M.; Baker, E. S.; Bredeweg, E. L.; Nosanchuk, J. D.; Nakayasu, E. S.

10.1101/2020.03.02.973412 — microbiology — Posted on 2021-03-06

4028 Revealing the relevant spatiotemporal scale underlying whole-brain dynamics

Kobeleva, X.; Lopez-Gonzalez, A.; Kringelbach, M.; Deco, G.

10.1101/2020.09.12.277699 — neuroscience — Posted on 2021-03-06

4029 Expectancy-based rhythmic entrainment as continuous Bayesian inference

Cannon, J. J.

10.1101/2020.11.05.369603 — neuroscience — Posted on 2021-03-06

4030 Smaller spared subcortical nuclei are associated with worse post-stroke sensorimotor outcomes in 28 cohorts worldwide

Liew, S.-L.; Zavaliangos-Petropulu, A.; Schweighofer, N.; Jahanshad, N.; Lang, C. E.; Lohse, K. R.; Banaj, N.; Barisano, G.; Baugh, L. A.; Bhattacharya, A. K.; Bigjahan, B.; Borich, M. R.; Boyd, L. A.; Brodtmann, A.; Buetefisch, C. M.; Byblow, W. D.; Cassidy, J. M.; Ciullo, V.; Conforto, A. B.; Craddock, R. C.; Dula, A. N.; Egorova, N.; Feng, W.; Fercho, K. A.; Gregory, C. M.; Hanlon, C. A.; Hayward, K. S.; Holguin, J. A.; Hordacre, B.; Hwang, D. H.; Kautz, S. A.; Khlif, M. S.; Kim, B.; Kuceyeski, A.; Liu, J.; Lo, B.; Lin, D.; Lotze, M.; Kim, H.; MacIntosh, B. J.; Margetis, J. L.; Mohamed, F.

10.1101/2020.11.04.366856 — neuroscience — Posted on 2021-03-06

4031 Hypothetical control of postural sway

Mangalam, M.; Kelty-Stephen, D. G.

10.1101/2020.05.19.104760 — neuroscience — Posted on 2021-03-06

4032 Antibiotic tolerance, persistence, and resistance of the evolved minimal cell, Mycoplasma mycoides JCVI-Syn3B.

Hossain, T.; Deter, H. S.; Peters, E. J.; Butzin, N. C.

10.1101/2020.06.02.130641 — synthetic biology — Posted on 2021-03-06

4033 Authentication of In Situ Measurements for Thoracic Aortic Aneurysms in Mice

Ohno-Urabe, S.; Kukida, M.; Franklin, M. K.; Katsumata, Y.; Su, W.; Gong, M. C.; Lu, H. S.; Daugherty, A.; Sawada, H.

10.1101/2020.12.24.424013 — pathology — Posted on 2021-03-06

4034 The methylation of SDC2 and TFPI2 defined three methylator phenotypes of colorectal cancer

Ruixue, L.; Yanteng, Z.; Kai, H.; Kangkang, W.; Tingting, L.; Haijun, Y.; Xianping, L.

10.1101/2021.03.03.433833 — cancer biology — Posted on 2021-03-06

4035 The M1 aminopeptidase NPEPPS is a novel regulator of cisplatin sensitivity

10.1101/2021.03.04.433676 — cancer biology — Posted on 2021-03-06

4036 Celda: A Bayesian model to perform co-clustering of genes into modules and cells into subpopulations using single-cell RNA-seq data

Wang, Z.; Yang, S.; Koga, Y.; Corbett, S. E.; Johnson, W. E.; Yajima, M.; Campbell, J. D.

10.1101/2020.11.16.373274 — bioinformatics — Posted on 2021-03-06

4037 MetaFusion: A high-confidence metacaller for filtering and prioritizing RNA-seq gene fusion candidates.

Apostolides, M.; Jiang, Y.; Husic, M.; Siddaway, R.; Hawkins, C.; Turinsky, A.; Brudno, M.; Ramani, A.

10.1101/2020.09.17.302307 — bioinformatics — Posted on 2021-03-06

4038 Whole Genome and Exome Sequencing Reference Datasets from A Multi-center and Cross-platform Benchmark Study

Zhao, Y.; Fang, L. T.; Shen, T.-W.; Choudhari, S.; Talsania, K.; Chen, J.; Shetty, J.; Kriga, Y.; Tran, B.; Zhu, B.; Chen, Z.; Chen, W.; Wang, C.; Jaeger, E.; Meerzaman, D.; Lu, C.; Idler, K.; Zheng, Y.; Shi, L.; Petitjean, V.; Sultan, M.; Hung, T.; Peters, E.; Drabek, J.; Vojta, P.; Maestro, R.; Gasparotto, D.; Koks, S.; Reimann, E.; Scherer, A.; Nordlund, J.; Liljedahl, U.; Foox, J.; Mason, C.; Xiao, C.; Xiao, W.

10.1101/2021.02.27.433136 — bioinformatics — Posted on 2021-03-06

4039 Recovery of high-qualitied Genomes from a deep-inland Salt Lake Using BASALT

Yu, K.; Qiu, Z.; Mu, R.; Qiao, X.; Zhang, L.; Lian, C.-A.; Deng, C.; Wu, Y.; Xu, Z.; Li, B.; Pan, B.; Zhang, Y.; Fan, L.; Liu, Y.; Cao, H.; Jin, T.; Chen, B.; Wang, F.; Yan, Y.; Xie, L.; Zhou, L.; Yi, S.; Chi, S.; Zhang, T.; Zhuang, W.

10.1101/2021.03.05.434042 — bioinformatics — Posted on 2021-03-06

4040 GraphProt2: A graph neural network-based method for predicting binding sites of RNA-binding proteins

Uhl, M.; Tran, D. V.; Heyl, F.; Backofen, R.

10.1101/850024 — bioinformatics — Posted on 2021-03-06

4041 Effect of Adolescent Stress on Adult Morphine-Induced Behavioral Sensitization is Dependent Upon Genetic Background

Kamens, H.; Miller, C.; Caulfield, J.; Zeid, D.; Horton, W.; Silva, C.; Sebastian, A.; Albert, I.; Gould, T.; Fishbein, D.; Grigson, P. S.; Cavigelli, S.

10.1101/2021.01.20.427504 — animal behavior and cognition — Posted on 2021-03-06

4042 BARcode DEmixing through Non-negative Spatial Regression (BarDensr)

Chen, S.; Loper, J.; Chen, X.; Zador, A. M.; Paninski, L.; Vaughan, A.

10.1101/2020.08.17.253666 — genomics — Posted on 2021-03-05

4043 Evolutionary priming and transition to the ectomycorrhizal habit in an iconic lineage of mushroom-forming fungi: is preadaptation a requirement?

Looney, B. P.; Miyauchi, S.; Morin, E.; Courty, P.-E.; Kohler, A. P.; Lindquist, E.; Kuo, A.; LaButti, K.; Pangilinan, J.; Lipzen, A.; Riley, R.; Andreopoulos, W.; He, G.; Johnson, J.; Nolan, M.; Tritt, A.; Barry, K. W.; Grigoriev, I. V.; Nagy, L. G.; Hibbett, D.; Henrissat, B.; Matheny, P. B.; Labbe, J.; Martin, F. M.

10.1101/2021.02.23.432530 — evolutionary biology — Posted on 2021-03-06

4044 Metabolic dissimilarity determines the establishment of cross-feeding interactions in bacteria

Giri, S.; Ona, L.; Waschina, S.; Shitut, S.; Yousif, G.; Kaleta, C.; Kost, C.

10.1101/2020.10.09.333336 — ecology — Posted on 2021-03-05

4045 Interleukin-10 suppression enhances T-cell antitumor immunity and responses to checkpoint blockade in chronic lymphocytic leukemia

Rivas, J. R.; Liu, Y.; Alhakeem, S. S.; Eckenrode, J. M.; Marti, F.; Collard, J. P.; Zhang, Y.; Shaaban, K. A.; Muthusamy, N.; Hildebrandt, G. C.; Fleischman, R. A.; Chen, L.; Thorson, J. S.; Leggas, M.; Bondada, S.

10.1101/2020.07.15.204560 — immunology — Posted on 2021-03-05

4046 Novel players and large-scale protein dynamics of BCR activation revealed by APEX2 proximity labelling of lipid rafts

Awoniyi, L. O.; Runsala, M.; Sustar, V.; Hernandez-Perez, S.; Sarapulov, A. V.; Petrov, P.; Mattila, P. K.

10.1101/2020.09.29.318766 — immunology — Posted on 2021-03-05

4047 NADPH Oxidase 2 Derived Reactive Oxygen Species Promote CD8+ T cell Effector Function

Chen, J.; Liu, C.; Chernatynskaya, A.; Newby, B. N.; Brusko, T. M.; Xu, X.; Morgan, N.; Santarlas, C. P.; Reeves, W. H.; Tse, H. M.; Leiding, J. W.; Mathews, C. E.

10.1101/2021.02.24.432756 — immunology — Posted on 2021-03-06

4048 Semaphorin3F Drives Dendritic Spine Pruning through Rho-GTPase Signaling

Duncan, B. W.; Mohan, V.; Wade, S. D.; Truong, Y.; Kampov-Polevoi, A.; Temple, B. R.; Maness, P. F.

10.1101/2021.03.05.433425 — neuroscience — Posted on 2021-03-05

4049 Effects of the selective dopamine D3 receptor antagonist PG01037 on morphine-induced hyperactivity and antinociception in mice

Botz-Zapp, C. A.; Foster, S. L.; Pulley, D. M.; Hempel, B.; Bi, G.-H.; Xi, Z.-X.; Newman, A. H.; Weinshenker, D.; Manvich, D. F.

10.1101/2020.04.07.029918 — neuroscience — Posted on 2021-03-05

4050 Dementia risk factors modify hubs but leave other connectivity measures unchanged in asymptomatic individuals: a graph theoretical analysis.

Clarke, H. J.; Messaritaki, E.; Dimitriadis, S. I.; Metzler-Baddeley, C.

10.1101/2020.10.08.331025 — neuroscience — Posted on 2021-03-05

4051 Trait Anxiety Effects on Late Phase Threatening Speech Processing: Evidence from EEG

Busch-Moreno, S.; Tuomainen, J.; Vinson, D.

10.1101/2020.10.02.323642 — neuroscience — Posted on 2021-03-05

4052 Modeling features of addiction with an oral oxycodone self-administration paradigm

Murphy, C.; Chang, Y.-H.; Pareta, R.; Li, J.-N.; Earnest, T.; Tooley, J. R.; Abiraman, K.; Vachez, Y. M.; Gereau, R.; Copits, B. A.; Kravitz, A. V.; Creed, M. C.

10.1101/2021.02.08.430180 — neuroscience — Posted on 2021-03-06

4053 A visual encoding model links magnetoencephalography signals to neural synchrony in human cortex

Kupers, E. R.; Benson, N. C.; Winawer, J.

10.1101/2020.04.19.049197 — neuroscience — Posted on 2021-03-06

4054 Data-driven learning how oncogenic gene expression locally alters heterocellular networks

Klinke, D. J.; Fernandez, A.; Deng, W.; Latifizadeh, H.; Pirkey, A. C.

10.1101/2020.05.04.077107 — systems biology — Posted on 2021-03-05

4055 A CTLA-4 nanobody improves the immunity of mice against challenges with Staphylococcus aureus and Streptococcus agalactiae

Wu, P.; Yang, N. n.; Xu, M. g.; chen, c.

10.1101/2021.03.05.434056 — cell biology — Posted on 2021-03-05

4056 Brucella outer membrane proteins to control maturation and antigen presentation of mouse dendritic cells

Yang, N.; Tong, Z.; chen, c.; Wang, Z.; Xu, M.; Zhang, Q.; Zhang, H.; Wang, Y.; Yi, J.; Sun, T.; Cui, B.; Jinfeng Xu,

10.1101/2021.03.05.434055 — microbiology — Posted on 2021-03-05

4057 Content bias in the cultural evolution of house finch song

Youngblood, M.; Lahti, D.

10.1101/2021.03.05.434109 — animal behavior and cognition — Posted on 2021-03-05

4058 sRNARFTarget: A fast machine-learning-based approach for transcriptome-wide sRNA Target Prediction

Naskulwar, K.; Pena-Castillo, L.

10.1101/2021.03.05.433963 — bioinformatics — Posted on 2021-03-05

4059 SARS-CoV-2-host chimeric RNA-sequencing reads do not necessarily signify virus integration into the host DNA

Kazachenka, A.; Kassiotis, G.

10.1101/2021.03.05.434119 — microbiology — Posted on 2021-03-05

4060 Scalable, Micro-Neutralization Assay for Qualitative Assessment of SARS-CoV-2 (COVID 19) Virus-Neutralizing Antibodies in Human Clinical Samples

Holbrook, M. R.; Bennett, R. S.; Postnikova, E. N.; Liang, J.; Gross, R.; Gerhardt, D.; Georgia-Clark, S.; Cai, Y.; Yu, S.; Marron, L.; Kocher, G.; Mazur, S.; Dixit, S.; Lukin, V. V.

10.1101/2021.03.05.434152 — immunology — Posted on 2021-03-05

4061 Mood and reward dynamics in human adolescent brain electrophysiology

Liuzzi, L.; Chang, K. K.; Keren, H.; Saha, D.; Zheng, C.; Nielson, D. M.; Stringaris, A.

10.1101/2021.03.04.433969 — neuroscience — Posted on 2021-03-05

4062 Novel personalized cancer vaccine platform based on Bacillus Calmette-Guerin

Ylosmaki, E.; Martins, B.; Fusciello, M.; Feola, S.; Hamdan, F.; Chiaro, J.; Ylosmaki, L.; Vaughan, M. J.; Viitala, T.; Kulkarni, P. S.; Cerullo, V.

10.1101/2021.03.05.434062 — cancer biology — Posted on 2021-03-05

4063 Analysis of SARS-CoV-2 Mutations Over Time Reveals Increasing Prevalence of Variants in the Spike Protein and RNA-Dependent RNA Polymerase

Showers, W. M.; Leach, S. M.; Kechris, K.; Strong, M.

10.1101/2021.03.05.433666 — bioinformatics — Posted on 2021-03-05

4064 Scent dog identification of SARS-CoV-2 infections, similar across different body fluids

Jendrny, P.; Twele, F.; Meller, S.; Schulz, C.; von Koeckritz-Blickwede, M.; Osterhaus, A.; Ebbers, H.; Ebbers, J.; Pilchova, V.; Pink, I.; Welte, T.; Manns, M. P.; Fathi, A.; Addo, M. M.; Ernst, C.; Schaefer, W.; Engels, M.; Petrov, A.; Marquart, K.; Schotte, U.; Schalke, E.; Volk, H. A.

10.1101/2021.03.05.434038 — animal behavior and cognition — Posted on 2021-03-05

4065 Comprehensive evolutionary analysis of complete Epstein Barr virus genomes from Argentina and other geographies

Blazquez, A. C.; Berenstein, A. J.; Torres, C.; Izquierdo, A.; Lezama, C.; Moscatelli, G.; De Matteo, E. N.; Lorenzetti, M. A.; Preciado, M. V.

10.1101/2021.03.05.434158 — evolutionary biology — Posted on 2021-03-05

4066 BORCS6 is involved in the enlargement of lung lamellar bodies in Lrrk2 knockout mice

Araki, M.; Ito, G.; Takatori, S.; Tomita, T.

10.1101/2021.03.05.434068 — cell biology — Posted on 2021-03-05

4067 Fine-tuned repression of Drp1 driven mitochondrial fission primes a slow cycling stem/progenitor-like state towards accelerating neoplastic transformation of keratinocytes

Mitra, K.; Spurlock, B. M.; Parker, D.; Basu, M.; Hjelmeland, A.; Gc, S.; Liu, S.; Siegal, G. P.; Gunter, A.; Moran, A.

10.1101/2021.03.05.434102 — cell biology — Posted on 2021-03-05

4068 Significance of the Wnt canonical pathway in radiotoxicity via oxidative stress of electron beam radiation and its molecular control in mice

Kumar, S.; Fathima, E.; Khanum, F.; Malini, S. S.

10.1101/2021.03.05.434047 — molecular biology — Posted on 2021-03-05

4069 Neutralization heterogeneity of United Kingdom and South-African SARS CoV-2 variants in BNT162b2-vaccinated or convalescent COVID-19 healthcare workers

Marot, S. S.; Malet, I.; Jary, A.; Leducq, V.; Abdi, B.; Teyssou, E.; Soulie, C.; Wirden, M.; Rodriguez, C.; Fourati, S.; Pawlotsky, J.-M.; Boutolleau, D.; Burrel, S.; Calvez, V.; Marcelin, A.-G.

10.1101/2021.03.05.434089 — microbiology — Posted on 2021-03-05

4070 High-Throughput and High-Dimensional Single Cell Analysis of Antigen-Specific CD8+ T cells

Ma, K.-Y.; Schonnesen, A. A.; He, C.; Xia, A. Y.; Sun, E.; Chen, E.; Sebastian, K. R.; Balderas, R.; Kulkarni-Date, M.; Jiang, N.

10.1101/2021.03.04.433914 — immunology — Posted on 2021-03-05

4071 Previous SARS-CoV-2 infection increases B.1.1.7 cross-neutralization by vaccinated individuals.

Trinite, B.; Pradenas, E.; Marfil, S.; Rovirosa, C.; Urrea, V.; Tarres-Freixas, F.; Ortiz, R.; Vergara-Alert, J.; Segales, J.; Guallar, V.; Lepore, A.; Izquierdo-Useros, N.; Trujillo, G.; Trape, J.; Gonzalez-Fernandez, C.; Flor, A.; Perez-Vidal, R.; Chamorro, A.; Toledo, R.; Paredes, R.; Blanco, I.; Grau, E.; Massanella, M.; Carrillo, J.; Clotet, B.; Blanco, J.

10.1101/2021.03.05.433800 — immunology — Posted on 2021-03-05

4072 Neurocomputational mechanisms of confidence in self and others

Bang, D.; Moran, R.; Daw, N. D.; Fleming, S. M.

10.1101/2021.03.05.434065 — neuroscience — Posted on 2021-03-05

4073 Tract-specific statistics based on diffusion-weighted probabilistic tractography

Reid, A. T.; Camilleri, J. A.; Hoffstaedter, F.; Eickhoff, S. B.

10.1101/2021.03.05.434061 — neuroscience — Posted on 2021-03-05

4074 runBioSimulations: an extensible web application that simulates a wide range of computational modeling frameworks, algorithms, and formats

Shaikh, B.; Marupilla, G.; Wilson, M.; Blinov, M. L.; Moraru, I. I.; Karr, J. R.

10.1101/2021.03.05.433787 — systems biology — Posted on 2021-03-05

4075 Oxaliplatin Resistance in Colorectal Cancer Enhances TRAIL Sensitivity Via Death Receptor 4 Upregulation and Lipid Raft Localization

Greenlee, J. D.; Lopez Cavestany, M.; Ortiz-Otero, N.; Liu, K.; Subramanian, T.; Cagir, B.; King, M. R.

10.1101/2021.03.05.434100 — cancer biology — Posted on 2021-03-05

4076 Mechanistic within-host models of the asexual Plasmodium falciparum infection: a review and analytical assessment

Camponovo, F.; Lee, T. E.; Russell, J.; Burgert, L.; Gerardin, J.; Penny, M. A.

10.1101/2021.03.05.434041 — bioinformatics — Posted on 2021-03-05

4077 Profiling transcription factor sub-networks in type I interferon signaling and in response to SARS-CoV-2 infection

Chilakamarti, R.

10.1101/2021.01.25.428122 — bioinformatics — Posted on 2021-03-05

4078 Recovery of high-qualitied Genomes from a deep-inland Salt Lake Using BASALT

10.1101/2021.03.05.434042 — bioinformatics — Posted on 2021-03-05

4079 Long noncoding RNA KCNQ1OT1 targets miRNA let-7a-5p to regulate Osteoarthritis development and progression

ramzan, h. s.; Ahmad, K. A.

10.1101/2021.03.05.434051 — biochemistry — Posted on 2021-03-05

4080 KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases

Huang, L.-C.; Taujale, R.; Gravel, N.; Venkat, A.; Yeung, W.; Byrne, D. P.; Eyers, P. A.; Kannan, N.

10.1101/2021.03.05.434161 — evolutionary biology — Posted on 2021-03-05

4081 Cumulative growth and stress responses to the 2018-2019 drought in a European floodplain forest

Schnabel, F.; Purrucker, S.; Schmitt, L.; Engelmann, R. A.; Kahl, A.; Richter, R.; Seele-Dilbat, C.; Skiadaresis, G.; Wirth, C.

10.1101/2021.03.05.434090 — ecology — Posted on 2021-03-05

4082 Public science data suggest that fish is the most important factor in reducing small pond biodiversity in Czechia

Hulcr, J.; Gomez, D. F.

10.1101/2021.03.05.434043 — ecology — Posted on 2021-03-05

4083 Post-embryonic development and aging of the appendicular skeleton in Ambystoma mexicanum

Riquelme-Guzman, C.; Schuez, M.; Böhm, A.; Knapp, D.; Rauner, M.; Sandoval-Guzman, T.

10.1101/2021.03.05.434057 — developmental biology — Posted on 2021-03-05

4084 An atypical class of non-coding small RNAs produced in rice leaves upon bacterial infection

Reshetnyak, G.; Jacobs, J. M.; Auguy, F.; Sciallano, C.; Claude, L.; Medina, C.; Perez Quintero, A.; Comte, A.; Thomas, E.; Bogdanove, A. J.; Koebnik, R.; Szurek, B.; Dievart, A.; Brugidou, C.; Lacombe, S.; Cunnac, S.

10.1101/2021.03.05.432875 — molecular biology — Posted on 2021-03-05

4085 Biosynthesis of benzoxazinoids in rye (Secale cereale L.) - where does the story begin?

Rakoczy-Trojanowska, M.; Rozanska, E.; Swiecicka, M.; Burza, W.; Bakera, B.; Kowalczyk, M.; Lotocka, B.; Szabala, B.

10.1101/2021.03.05.434075 — molecular biology — Posted on 2021-03-05

4086 Host-directed FDA-approved drugs with antiviral activity against SARS-CoV-2 identified by hierarchical in silico/in vitro screening methods

Ginez, T.; Garaigorta, U.; Ramirez, D.; Castro, V.; Nozal, V.; Maestro, I.; Garcia-Carceles, J.; Campillo, N. E.; Martinez, A.; Gastaminza, P.; Gil, C.

10.1101/2020.11.26.399436 — microbiology — Posted on 2021-03-05

4087 A recombinant selective drug-resistant M. bovis BCG enhances the bactericidal activity of a second-line tuberculosis regimen

Chiwala, G.; Liu, Z.; Mugweru, J. N.; Wang, B.; Khan, S. A.; Bate, P. N. N.; Yusuf, B.; Hameed, H. M. A.; Fang, C.; Tan, Y.; Guan, P.; Hu, J.; Tan, S.-Y.; Liu, J.; Zhong, N.; Zhang, T.

10.1101/2021.03.04.434024 — microbiology — Posted on 2021-03-05

4088 Bispecific antibody neutralizes circulating SARS-CoV-2 variants, prevents escape and protects mice from disease

De Gasparo, R.; Pedotti, M.; Simonelli, L.; Nickl, P.; Muecksch, F.; Cassaniti, I.; Percivalle, E.; Lorenzi, J. C. C.; Mazzola, F.; Magri, D.; Michalcikova, T.; Haviernik, J.; Honig, V.; Mrazkova, B.; Polakova, N.; Fortova, A.; Tureckova, J.; Iatsiuk, V.; Di Girolamo, S.; Palus, M.; Zudova, D.; Bednar, P.; Bukova, I.; Bianchini, F.; Mehn, D.; Nencka, R.; Strakova, P.; Pavlis, O.; Rozman, J.; Gioria, S.; Sammartino, J. C.; Giardina, F.; Gaiarsa, S.; Hammarström, Q. P.; Barnes, C. O.; Bjorkman, P. J.; Calzolai, L.; Piralla, A.; Baldanti, F.; Nussenzweig, M. C.; Bieniasz, P. D.; Hatziioannou, T.

10.1101/2021.01.22.427567 — immunology — Posted on 2021-03-05

4089 Microchannel patterning strategies for in vitro structural connectivity modulation of neural networks

Maisonneuve, B. G. C.; Vieira, J.; Larramendy, F.; Honegger, T.

10.1101/2021.03.05.434080 — neuroscience — Posted on 2021-03-05

4090 In vivo high-throughput screening of novel adeno-associated viral capsids targeting adult neural stem cells in the subventricular zone

Dehler, S.; Kremer, L. P.; Cerrizuela, S.; Stiehl, T.; Weinmann, J.; Abendroth, H.; Kleber, S.; Laure, A.; Andari, J. E.; Anders, S.; Marciniak-Czochra, A.; Grimm, D.; Martin-Villalba, A.

10.1101/2021.03.05.434064 — neuroscience — Posted on 2021-03-05

4091 Diffusional Kurtosis Imaging in the Diffusion Imaging in Python Project

Henriques, R. N.; Correia, M. M.; Maralle, M.; Huber, E.; Kruper, J.; Koudoro, S.; Yeatman, J. D.; Garyfallidis, E.; Rokem, A.

10.1101/2021.03.04.433972 — neuroscience — Posted on 2021-03-05

4092 Multiomics Analyses Reveal Dynamic Bioenergetic Pathways and Functional Remodeling of the Heart During Intermittent Fasting

Arumugam, T. V.; Alli-Shaik, A.; Liehn, E. A.; Selvaraji, S.; Poh, L.; Rajeev, V.; Kim, J.; Swa, H. L. F.; Hao, D. T. Z.; Ratttanasopa, C.; Fann, D. Y.-W.; Mayan, D. C.; Ng, G. Y.-Q.; Baik, S.-H.; Mallilankaraman, K.; Gelderblom, M.; Drummond, G. R.; Sobey, C. G.; Kennedy, B. K.; Jo, D.-G.; Singaraja, R. R.; Mattson, M. P.; Gunaratne, J.

10.1101/2021.03.04.433999 — systems biology — Posted on 2021-03-05

4093 Artificial intelligence enables the identification and quantification of arbuscular mycorrhizal fungi in plant roots

Evangelisti, E.; Turner, C.; McDowell, A.; Shenhav, L.; Yunusov, T.; Gavrin, A.; Servante, E. K.; Quan, C.; Schornack, S.

10.1101/2021.03.05.434067 — plant biology — Posted on 2021-03-05

4094 Gut markers of bodily self-consciousness

Monti, A.; Porciello, G.; Panasiti, M. S.; Aglioti, S. M.

10.1101/2021.03.05.434072 — physiology — Posted on 2021-03-05

4095 Blockade of SARS-CoV-2 infection in-vitro by highly potent PI3K-α/mTOR/BRD4 inhibitor

Acharya, A.; Pandey, K.; Thurman, M.; Challagundla, K. B.; Vann, K. R.; Kutateladze, T. G.; Morales, G. A.; Durden, D. L.; Byrareddy, S. N.

10.1101/2021.03.02.433604 — pharmacology and toxicology — Posted on 2021-03-05

4096 Zebrafish embryo screen identifies anti-metastasis drugs

Nakayama, J.; Tan, L.; Goh, B. C.; Wang, S.; Makinoshima, H.; Zhiyuan, G.

10.1101/2021.03.04.434001 — cancer biology — Posted on 2021-03-05

4097 DMWAS: Deep Machine learning omics Wide Association Study & Feature set optimization by clustering & univariate association for Biomarkers discovery as tested on GTEx pilot dataset for death due to heart-attack

Singh, A. N.

10.1101/2021.03.04.433958 — bioinformatics — Posted on 2021-03-05

4098 ChromeBat: A Bio-Inspired Approach to 3D Genome Reconstruction

Collins, B.; Brown, P. N.; Oluwadare, O.

10.1101/2021.03.04.433995 — bioinformatics — Posted on 2021-03-05

4099 Ontoclick: a Chrome web browser extension to facilitate biomedical knowledge curation

Xu, A.; Venkateswaran, A.; Zhou, L.; Zankl, A.

10.1101/2021.03.04.433993 — bioinformatics — Posted on 2021-03-05

4100 Robust optical autofocus system utilizing neural networks trained for extended range and time-course and automated multiwell plate imaging including single molecule localization microscopy

Lightley, J.; Görlitz, F.; Kumar, S.; Kalita, R.; Kolbeinsson, A.; Garcia, E.; Alexandrov, Y.; Bousgouni, V.; Wysoczanski, R.; Barnes, P.; Donnelly, L.; Bakal, C.; Dunsby, C.; Neil, M. A. A.; Flaxman, S.; French, P. M. W.

10.1101/2021.03.05.431171 — bioengineering — Posted on 2021-03-05

4101 Monitoring deep-tissue oxygenation with a millimeter-scale ultrasonic implant

Sonmezoglu, S.; Fineman, J. R.; Maltepe, E.; Maharbiz, M. M.

10.1101/2021.03.05.434129 — bioengineering — Posted on 2021-03-05

4102 Multi-Species Phenotypic Screening across Disease Models of Mucolipidosis Type IV

Hadjikyriacou, A.; Iyer, S.; Mast, J. D.; DiPrimio, N.; Concannon, J.; Ketterman, J.; Sigoillot, F.; Rodriguez, T. P.; Sam, F. S.; Tsang, H.; Prangley, M.; Bilen, J.; Murthy, K.; Hartl, T. A.; Antczak, C.; Jenkins, J. L.; Ross, N. T.; Nyfeler, B.; Jain, R. K.; Tallarico, J. A.; Perlstein, E. O.; Canham, S. M.

10.1101/2021.03.05.434120 — cell biology — Posted on 2021-03-05

4103 Modulation of fatty acid elongation generates sexually dimorphic hydrocarbons and female attractiveness in Blattella germanica (L.)

Pei, X.-J.; Fan, Y.-L.; Bai, Y.; Bai, T.-T.; Schal, C.; Zhang, Z.-F.; Chen, N.; Li, S.; Liu, T.-X.

10.1101/2021.03.04.434003 — molecular biology — Posted on 2021-03-05

4104 A multiepitope fusion protein-based p-ELISA method for diagnosing bovine and goat brucellosis

Yin, D.; Bai, Q.; Wu, X.; Li, H.; Shao, J.; Sun, M.; Zhang, J.

10.1101/2021.03.04.434020 — microbiology — Posted on 2021-03-05

4105 Ecological relevance of abundant and rare taxa in a high-diverse elastic hypersaline microbial mat, using a small-scale sampling

Espinosa-Asuar, L.; Monroy, C.; Madrigal-Trejo, D.; Navarro, M.; Sanchez, J.; Munoz, J.; Villar, J. D.; Cifuentes, J.; Kalambokidis, M.; Esquivel-Hernandez, D. A.; Viladomat, M.; Escalante-Hernandez, A. E.; Velez, P.; Figueroa, M.; Ramirez Barahona, S.; Gasca-Pineda, J.; Eguiarte, L. E.; Souza, V.

10.1101/2021.03.04.433984 — microbiology — Posted on 2021-03-05

4106 A bacterial signal transduction phosphorelay in the methanogenic archaeon Methanosarcina acetivorans

Frankenberg-Dinkel, N.; Sexauer, A.

10.1101/2021.03.04.434021 — microbiology — Posted on 2021-03-05

4107 A selective sweep in the Spike gene has driven SARS-CoV-2 human adaptation

Kang, L.; He, G.; Sharp, A. K.; Wang, X.; Brown, A. M.; Michalak, P.; Weger-Lucarelli, J.

10.1101/2021.02.13.431090 — microbiology — Posted on 2021-03-05

4108 Identification and quantification of SARS-CoV-2 leader subgenomic mRNA gene junctions in nasopharyngeal samples shows phasic transcription in animal models of COVID-19 and dysregulation at later time points that can also be identified in humans

Penrice-Randal, R.; Goldswain, H.; Prince, T.; Randle, N.; Salguero, J.; Tree, J.; Vamos, E.; Nelson, C.; Stewart, J. P.; ISARIC-4C Investigators, ; COG-UK Consortium, ; Semple, M. G.; Baillie, J. K.; Openshaw, P. J. M.; Turtle, L.; Matthews, D. A.; Carroll, M. W.; Darby, A.; Hiscox, J. A.

10.1101/2021.03.03.433753 — microbiology — Posted on 2021-03-05

4109 Honeybees exposure to veterinary drugs: how the gut microbiota is affected

Baffoni, L.; Alberoni, D.; Gaggia, F.; Braglia, C.; Stanton, C.; Ross, R. P.; Di Gioia, D.

10.1101/2021.03.04.434023 — microbiology — Posted on 2021-03-05

4110 Estimation of in-scanner head pose changes during structural MRI using a convolutional neural network trained on eye tracker video

Pardoe, H. R.; Martin, S. P.; Zhao, Y.; George, A.; Yuan, H.; Zhou, J.; Liu, W.; Devinsky, O.

10.1101/2021.03.04.433975 — neuroscience — Posted on 2021-03-05

4111 Modulation of tactile feedback for the execution of dexterous movement

Conner, J. M.; Bohannon, A.; Igarashi, M.; Taniguchi, J.; Baltar, N.; Azim, E.

10.1101/2021.03.04.433649 — neuroscience — Posted on 2021-03-05

4112 Correlative light and electron microscopy reveals that mutant huntingtin dysregulates the endolysosomal pathway in presymptomatic Huntington's disease

Zhou, Y.; Peskett, T. R.; Landles, C.; Warner, J. B.; Sathasivam, K.; Smith, E. J.; Chen, S.; Wetzel, R.; Lashuel, H. A.; Bates, G. P.; Saibil, H. R.

10.1101/2021.03.05.433899 — neuroscience — Posted on 2021-03-05

4113 Evolutionary optimization in classification of early-MCI patients from healthy controls using graph measures of resting-state fMRI

Zamani, J.; Sadr, A.; Javadi, A.-H.

10.1101/2021.03.04.433989 — neuroscience — Posted on 2021-03-05

4114 Hypnotic visual hallucination induces greater lateralised brain activity than visual imagery

Lanfranco, R. C.; Rivera-Rei, A.; Huepe, D.; Ibanez, A.; Canales-Johnson, A.

10.1101/2021.03.04.434014 — neuroscience — Posted on 2021-03-05

4115 Reconstruction of a catalogue of genome-scale metabolic models with enzymatic constraints using GECKO 2.0

Domenzain, I.; Sanchez, B.; Anton, M.; Kerkhoven, E. J.; Millan-Oropeza, A.; Henry, C.; Siewers, V.; Morrisey, J. P.; Sonnenschein, N.; Nielsen, J.

10.1101/2021.03.05.433259 — systems biology — Posted on 2021-03-05

4116 Underground Heterosis for Melons Yield

Dafna, A.; Halperin, I.; Oren, E.; Isaacson, T.; Tzuri, G.; Meir, A.; Schaffer, A. A.; Burger, J.; Tadmor, Y.; Buckler, E. S.; Gur, A.

10.1101/2021.03.04.434025 — plant biology — Posted on 2021-03-05

4117 A cell wall invertase controls nectar volume and sugar composition

Minami, A.; Kang, X.; Carter, C. J.

10.1101/2021.03.05.434125 — plant biology — Posted on 2021-03-05

4118 Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle

Rhein, P.; Desjardins, E. M.; Rong, P.; Ahwazi, D.; Bonhoure, N.; Stolte, J.; Santos, M. D.; Ovens, A. J.; Ehrlich, A. M.; Sanchez Garcia, J. L.; Ouyang, Q.; Kjolby, M. F.; Membrez, M.; Jessen, N.; Oakhill, J. S.; Treebak, J. T.; Maire, P.; Scott, J. W.; Sanders, M. J.; Descombes, P.; Chen, S.; Steinberg, G. R.; Sakamoto, K.

10.1101/2021.03.05.433354 — physiology — Posted on 2021-03-05

4119 Simulation of a sudden drop-off in distal dense core vesicle concentration in Drosophila type II motoneuron terminals

Kuznetsov, I. A.; Kuznetsov, A. V.

10.1101/2021.03.04.434010 — bioengineering — Posted on 2021-03-05

4120 Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2

10.1101/2021.03.05.434000 — biochemistry — Posted on 2021-03-05

4121 Transcriptional regulation of schizophrenia risk gene TCF4 in inhibitory neurons during neurodevelopment

wang, y.; lin, m.

10.1101/2021.03.04.433878 — genomics — Posted on 2021-03-05

4122 Insights from the first genome assembly of Onion (Allium cepa)

Finkers, R.; van Kaauwen, M. P. W.; Ament, K.; Burger-Meijer, K.; Egging, R. J.; Huits, H.; Kodde, L. P.; Kroon, L.; Shigyo, M.; Sato, S.; Vosman, B.; van Workum, W. A. T.; Scholten, O.

10.1101/2021.03.05.434149 — genomics — Posted on 2021-03-05

4123 Climate and genetic diversity change in mammals during the Late Quaternary

Theodoridis, S.; Florez Rodriguez, A.; Truelsen, D. M.; Giampoudakis, K.; Garcia, R. A.; Singarayer, J.; Valdes, P.; Rahbek, C.; Marske, K. A.; Nogues-Bravo, D.

10.1101/2021.03.05.433883 — ecology — Posted on 2021-03-05

4124 A genetic screen for regulators of muscle morphogenesis in Drosophila

Johnson, A. N.; Skeath, J. B.; Ou, T.; Wilson, B.; Gontarz, P.; Huang, G.

10.1101/2021.03.04.434006 — developmental biology — Posted on 2021-03-05

4125 Preparation of functional IgY that potently neutralizes HIV-1 in TZM-bl Cell line

jingchen, W.; Yanqun, Z.; Yonglian, Z.; Yang, Y.; Ronggan, L.; Chengqin, L.; Zhigang, D.; Songqing, H.; Shuwen, W.; qing, x.

10.1101/2021.03.04.431083 — immunology — Posted on 2021-03-05

4126 Elevation of TRPV1 expression on T cells during experimental immunosuppression

Kumar, P. S.; Mukherjee, T.; Khamaru, S.; Kishore, D. J. N.; Chawla, S.; Sahoo, S. S.; Chattopadhyay, S.

10.1101/2021.03.04.434013 — immunology — Posted on 2021-03-05

4127 Differential levels of IFNα subtypes in autoimmunity and viral infection

Bondet, V.; Rodero, M. P.; Posseme, C.; Bost, P.; Decalf, J.; Haljasmagi, L.; Bekaddour, N.; Rice, G.; Upasani, V.; Herbeuval, J.-P.; Reynolds, J. A.; Briggs, T. A.; Bruce, I. N.; Mauri, C.; Isenberg, D.; Menon, M.; Hunt, D.; Schwikowski, B.; Mariette, X.; Pol, S.; Rozenberg, F.; Cantaert, T.; Gottenberg, J.-E.; Kisand, K.; Duffy, D.

10.1101/2021.03.04.433900 — immunology — Posted on 2021-03-05

4128 Molecular strategies for antibody binding and escape of SARS-CoV-2 and its mutations

Hendy, M.; Kaufman, S.; Ponga, M.

10.1101/2021.03.04.433970 — biophysics — Posted on 2021-03-05

4129 Decreased KATP channel activity contributes to the low glucose threshold for insulinsecretion in the early postnatal period

Yang, J.; Hammoud, B.; Li, C.; Ridler, A.; Yau, D.; Kim, J.; Won, K.-J.; Stanley, C. A.; Hoshi, T.; Stanescu, D. E.

10.1101/2021.03.04.433947 — developmental biology — Posted on 2021-03-05

4130 Zoonotic spillover of SARS-CoV-2: mink-adapted virus in humans

Rabalski, L.; Kosinski, M.; Mazur-Panasiuk, N.; Szewczyk, B.; Bienkowska-Szewczyk, K.; Kant, R.; Sironen, T.; Pyrc, K.; Grzybek, M.

10.1101/2021.03.05.433713 — microbiology — Posted on 2021-03-05

4131 IgM+ and IgG+ memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with P. yoelii.

Brown, S. L.; Bauer-Erikson, J. J.; Lee, J.; Ntirandekura, E.; Stumhofer, J. S.

10.1101/2021.03.04.433964 — immunology — Posted on 2021-03-05

4132 Acyloxyacyl Hydrolase Modulates the Gut Microbiome Through Transcriptional Regulators of Corticotropin-Releasing Factor

Rahman-Enyart, A.; Aguiniga, L. M.; Yang, W.; Yaggie, R. E.; White, B.; Welge, M.; Auvil, L.; Berry, M.; Bushell, C.; Schaeffer, A. J.; Klumpp, D. J.

10.1101/2021.03.04.433950 — systems biology — Posted on 2021-03-05

4133 Efficient generative modeling of protein sequences using simple autoregressive models

Trinquier, J.; Uguzzoni, G.; Pagnani, A.; Zamponi, F.; Weigt, M.

10.1101/2021.03.04.433959 — bioinformatics — Posted on 2021-03-05

4134 Positional SHAP for Interpretation of Deep Learning Models Trained from Biological Sequences

Dickinson, Q.; Meyer, J. G.

10.1101/2021.03.04.433939 — bioinformatics — Posted on 2021-03-05

4135 Collaborative Cross Founder Expression Analysis (CCFEA)

Green, R. R.; Ireton, R. C.; Ferris, M.; Muenzen, K.; Crosslin, D. R.; Gale, M.

10.1101/2021.03.04.422591 — bioinformatics — Posted on 2021-03-05

4136 Glucagon-like peptide 1 receptor-mediated stimulation of a GABAergic projection from the bed nucleus of the stria terminalis to the hypothalamic paraventricular nucleus

Povysheva, N.; Zheng, H.; Rinaman, L.

10.1101/2021.03.04.433953 — neuroscience — Posted on 2021-03-05

4137 Non-ionotropic NMDA receptor signaling alters structural plasticity of dendritic spines in a mouse model of schizophrenia

Park, D. K.; Stein, I. S.; Barragan, E. V.; Gray, J. A.; Zito, K.

10.1101/2021.03.04.434016 — neuroscience — Posted on 2021-03-05

4138 Deep Diffusion MRI Registration (DDMReg): A Deep Learning Method for Diffusion MRI Registration

Zhang, F.; Wells, W. M.; O'Donnell, L. J.

10.1101/2021.03.04.433968 — neuroscience — Posted on 2021-03-05

4139 Mutation Profiles, Glycosylation Site Distribution and Codon Usage Bias of HPV16

Ou, Z.; Liu, W.; LI, J.; Du, H.

10.1101/2021.03.04.434005 — genomics — Posted on 2021-03-05

4140 Mutation load decreases with haplotype age in wild Soay sheep

Stoffel, M. A.; Johnston, S. E.; Pilkington, J. G.; Pemberton, J. M.

10.1101/2021.03.04.433700 — evolutionary biology — Posted on 2021-03-05

4141 GroEL/S helps purge deleterious mutations and reduce genetic diversity during adaptive protein evolution

Iyengar, B. R.; Wagner, A.

10.1101/2021.03.05.434078 — evolutionary biology — Posted on 2021-03-05

4142 Selective sorting of ancestral introgression in maize and teosinte along an elevational cline

Calfee, E.; Gates, D.; Lorant, A.; Perkins, M. T.; Coop, G.; Ross-Ibarra, J.

10.1101/2021.03.05.434040 — evolutionary biology — Posted on 2021-03-05

4143 The enpp4 ectonucleotidase regulates kidney patterning signalling networks in Xenopus embryos

Masse, K.; Bhamra, S.; Paroissin, C.; Maneta-Peyret, L.; Boue-Grabot, E.; Jones, E. A.

10.1101/2021.03.04.433320 — developmental biology — Posted on 2021-03-05

4144 Thermosensation as a novel method to probe interoception and its relationship with other interoceptive modalities

Crucianelli, L.; Enmalm, A.; Ehrsson, H. H.

10.1101/2021.03.04.433866 — neuroscience — Posted on 2021-03-05

4145 GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton

Wolf, C.; Pouya, A.; Bitar, S.; Pfeiffer, A.; Bueno, D.; Arndt, S.; Tenzer, S.; Ritz, S.; Schwirz, J.; Dobrindt, K.; Peitz, M.; Bruestle, O.; Dal Bello, F.; Vianello, C.; Giacomello, M.; Hanschmann, E.-M.; Boussaad, I.; Krueger, R.; Methner, A.

10.1101/2021.03.04.433895 — neuroscience — Posted on 2021-03-05

4146 TAFKAP: An improved method for probabilistic decoding of cortical activity

van Bergen, R. S.; Jehee, J. F. M.

10.1101/2021.03.04.433946 — neuroscience — Posted on 2021-03-05

4147 NeuroModulation Modeling (NMM): Inferring the form of neuromodulation from fMRI tuning functions

Sadil, P.; Huber, D. E.; Cowell, R. A.

10.1101/2021.03.04.433362 — neuroscience — Posted on 2021-03-05

4148 Conserved structures of neural activity in sensorimotor cortex of freely moving rats allow cross-subject decoding

Melbaum, S.; Eriksson, D.; Brox, T.; Diester, I.

10.1101/2021.03.04.433869 — neuroscience — Posted on 2021-03-05

4149 Preoptic BRS3 neurons increase body temperature and heart rate via multiple pathways

Piñol, R. A.; Mogul, A. S.; Hadley, C. K.; Saha, A.; Li, C.; Skop, V.; Province, H. S.; Xiao, C.; Gavrilova, O.; Krashes, M. J.; Reitman, M. L.

10.1101/2021.03.04.433948 — neuroscience — Posted on 2021-03-05

4150 Spinal Cord Injury Reduces Serum Levels of Fibroblast Growth Factor-21 and Impairs its Signaling Pathways in Liver and Adipose Tissue in Mice

Liu, X.-h.; Graham, Z. A.; Harlow, L.; Pan, J.; Azulai, D.; Bauman, W. A.; Yarrow, J.; Cardozo, C. P.

10.1101/2021.03.04.433932 — physiology — Posted on 2021-03-05

4151 Stem canker caused by Phomopsis spp. induces changes in polyamine levels and chlorophyll fluorescence parameters in pecan leaves

Mantz, G. M.; Rossi, F. R.; Viretto, P. E.; Noelting, M. C.; Maiale, S. J.

10.1101/2021.03.04.433926 — pathology — Posted on 2021-03-05

4152 Structural basis for the coiled-coil architecture of human CtIP

Morton, C. R.; Rzechorzek, N. J.; Maman, J. D.; Kuramochi, M.; Sekiguchi, H.; Rambo, R. P.; Sasaki, Y. C.; Davies, O. R.; Pellegrini, L.

10.1101/2021.03.05.434060 — biophysics — Posted on 2021-03-05

4153 TRAIT2D: a Software for Quantitative Analysis of Single Particle Diffusion Data

Reina, F.; Wigg, J. M. A.; Dmitrieva, M.; Lefebvre, J.; Rittscher, J.; Eggeling, C.

10.1101/2021.03.04.433888 — bioinformatics — Posted on 2021-03-05

4154 Constrained standardization of count data from massive parallel sequencing

Van Houtven, J.; Cuypers, B.; Meysman, P.; Hooyberghs, J.; Laukens, K.; Valkenborg, D.

10.1101/2021.03.04.433870 — bioinformatics — Posted on 2021-03-05

4155 Network pharmacology of lycopene and Molecular Docking with Top Hub Proteins

Paudel, N.; Umme, H.; Awasthi, N. P.; Hanumantappa, M.; Lakshminarayana, R.

10.1101/2021.03.04.433249 — bioinformatics — Posted on 2021-03-05

4156 Overall performance and taxonomic bias of antimicrobial peptide prediction tools in invertebrates

Radai, Z.; Kiss, J.

10.1101/2021.03.04.433925 — bioinformatics — Posted on 2021-03-05

4157 Inhibitory properties of microalgal extracts on the in vitro replication of cyprinid herpesvirus 3

Fritzsche, S.; Blenk, P.; Christian, J.; Castiglione, K.; Becker, A. M.

10.1101/2021.03.05.434077 — bioengineering — Posted on 2021-03-05

4158 Bovine milk somatic cell transcriptomic response to Staphylococcus aureus is dependent on strain genotype

Niedziela, D. A.; Cormican, P.; Foucras, G.; Leonard, F. C.; Keane, O. M.

10.1101/2021.03.04.433893 — genomics — Posted on 2021-03-05

4159 The role of H3K36 methylation and associated methyltransferases in chromosome-specific gene regulation

Lindehell, H.; Glotov, A.; Dorafshan, E.; Schwartz, Y. B.; Larsson, J.

10.1101/2021.03.04.433843 — genetics — Posted on 2021-03-05

4160 Long runs of homozygosity are correlated with marriage preferences across global population samples

Sahoo, S. A.; Zaidi, A. A.; Mathieson, I.; Anagol, S.

10.1101/2021.03.04.433907 — genetics — Posted on 2021-03-05

4161 Projecting climate-driven shifts in demersal fish habitat in Iceland's waters

Mason, J. G.; Woods, P. J.; Thorlacius, M.; Guthnason, K.; Saba, V. S.; Sullivan, P. J.; Kleisner, K. M.

10.1101/2021.03.04.433927 — ecology — Posted on 2021-03-05

4162 Stable nitrogen isotope analysis of amino acids as a new tool to clarify complex parasite-host interactions within marine food webs

Riekenberg, P. M.; Joling, T.; IJsseldijk, L. L.; Waser, A. M.; van der Meer, M. T. J.; Thieltges, D. W.

10.1101/2021.03.04.433913 — ecology — Posted on 2021-03-05

4163 N6-methyladenosine RNA modification regulates strawberry fruit ripening in an ABA-dependent manner

Zhou, L.; Tang, R.; Li, X.; Tian, S.; Li, B.; Qin, G.

10.1101/2021.03.04.433875 — developmental biology — Posted on 2021-03-05

4164 Intestine-enriched apolipoprotein b orthologs regulate stem cell differentiation and regeneration in planarians

Wong, L. L.; Bruxvoort, C. G.; Cejda, N. I.; Rodriguez Otero, J.; Forsthoefel, D. J.

10.1101/2021.03.04.433904 — developmental biology — Posted on 2021-03-05

4165 Scaling dictates the decoder structure

Shen, J.; Liu, F.; Tang, C.

10.1101/2021.03.04.433820 — developmental biology — Posted on 2021-03-05

4166 Cellular abundance shapes function in piRNA-guided genome defense

Genzor, P.; Konstantinidou, P.; Stoyko, D.; Manzourolajdad, A.; Marlin Andrews, C.; Elchert, A. R.; Stathopoulos, C.; Haase, A. D.

10.1101/2021.03.04.433912 — developmental biology — Posted on 2021-03-05

4167 Focal Laser Stimulation of Fly Nociceptors Activates Distinct Axonal and Dendritic Ca2+ Signals

Basak, R.; Sutradhar, S.; Howard, J.

10.1101/2021.03.04.433797 — neuroscience — Posted on 2021-03-05

4168 Smartphone deprivation alters cortical sensorimotor processing of the hand

Ghosh, A.

10.1101/2021.03.04.433898 — neuroscience — Posted on 2021-03-05

4169 Memory shapes microbial populations

Gokhale, C. S.; Giamo, S.; Remigi, P.

10.1101/2020.11.05.370106 — microbiology — Posted on 2021-03-05

4170 DUBStepR: correlation-based feature selection for clustering single-cell RNA sequencing data

Ranjan, B.; Sun, W.; Park, J.; Mishra, K.; Xie, R.; Alipour, F.; Singhal, V.; Schmidt, F.; Joanito, I.; Arul Rayan, N.; Gek Liang Lim, M.; Prabhakar, S.

10.1101/2020.10.07.330563 — bioinformatics — Posted on 2021-03-05

4171 Brain expression quantitative trait locus and network analysis reveals downstream effects and putative drivers for brain-related diseases

de Klein, N.; Tsai, E. A.; Vochteloo, M.; Baird, D.; Huang, Y.; Chen, C.-Y.; van Dam, S.; Deelen, P.; Bakker, O.; El Garwany, O.; Ouyang, Z.; Marshall, E.; Zavodszky, M.; van Rheenen, W.; Bakker, M. K.; Veldink,, J. H.; Gaunt, T.; Runz, H.; Franke, L.; Westra, H.-J.

10.1101/2021.03.01.433439 — genomics — Posted on 2021-03-05

4172 Evidence for shared ancestry between Actinobacteria and Firmicutes bacteriophages

Koert, M.; Lopez-Perez, J.; Mattson, C.; Caruso, S. M.; Erill, I.

10.1101/842583 — genomics — Posted on 2021-03-05

4173 Single nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell type-specific gene regulatory variation

Gui, Y.; Grzyb, K.; Thomas, M. H.; Ohnmacht, J.; Garcia, P.; Buttini, M.; Skupin, A.; Sauter, T.; Sinkkonen, L.

10.1101/2020.06.10.144626 — genomics — Posted on 2021-03-05

4174 Genetic analyses identify widespread sex-differential participation bias

Pirastu, N.; Cordioli, M.; Nandakumar, P.; Mignogna, G.; Abdellaoui, A.; Hollis, B.; Kanai, M.; Rajagopal, V. M.; Della Briotta Parolo, P.; Baya, N.; Carey, C.; Karjalainen, J.; Als, T. D.; van der Zee, M. D.; Day, F. R.; Ong, K. K.; 23andMe Research Team, ; iPSYCH Consortium, ; Morisaki, T.; de Geus, E.; Bellocco, R.; Okada, Y.; Borglum, A.; Joshi, P. K.; Auton, A.; Hinds, D. K.; Neale, B.; Walters, R. K.; Nivard, M. G.; Perry, J.; Ganna, A.

10.1101/2020.03.22.001453 — genetics — Posted on 2021-03-05

4175 Stabilising effects of competition and diversity determine vaccine impact on antibiotic resistance evolution

Davies, N. G.; Flasche, S.; Jit, M.; Atkins, K. E.

10.1101/610188 — evolutionary biology — Posted on 2021-03-05

4176 Performance of a phylogenetic independent contrast method and an improved pairwise comparison under different scenarios of trait evolution after speciation and duplication

Begum, T.; Serrano-Serrano, M. L.; Robinson-Rechavi, M.

10.1101/2020.09.25.313353 — evolutionary biology — Posted on 2021-03-05

4177 Landscape connectivity alters the evolution of density-dependent dispersal during pushed range expansions

Dahirel, M.; Bertin, A.; Calcagno, V.; Duraj, C.; Fellous, S.; Groussier, G.; Lombaert, E.; Mailleret, L.; Marchand, A.; Vercken, E.

10.1101/2021.03.03.433752 — ecology — Posted on 2021-03-05

4178 A dynamic occupancy model for interacting species with two spatial scales

Kleiven, E. F.; Barraquand, F.; Gimenez, O.; Henden, J.-A.; Ims, R. A.; Soininen, E. M.; Yoccoz, N. G.

10.1101/2020.12.16.423067 — ecology — Posted on 2021-03-05

4179 Patterns of multisensory facilitation distinguish peripersonal from reaching space

Zanini, A.; Patane, I.; Blini, E.; Salemme, R.; Koun, E.; Farne, A.; Brozzoli, C.

10.1101/2020.06.01.127282 — neuroscience — Posted on 2021-03-05

4180 Neural encoding of reliability of directional information during the preparation of targeted movements

Tzagarakis, C.; West, S.; Pellizzer, G.

10.1101/2020.09.17.302000 — neuroscience — Posted on 2021-03-05

4181 Paracrine behaviors arbitrate parasite-like interactions between tumor subclones

Noble, R. J.; Walther, V.; Roumestand, C.; Hibner, U.; Hochberg, M. E.; Lassus, P.

10.1101/2020.12.14.422649 — cancer biology — Posted on 2021-03-05

4182 Discovery and validation of novel human genomic safe harbor sites for gene and cell therapies

Aznauryan, E.; Yermanos, A.; Kinzina, E.; Kapetanovic, E.; Milanova, D.; Church, G.; Reddy, S.

10.1101/2021.03.04.433856 — genomics — Posted on 2021-03-05

4183 Molecular mechanism regulating transcriptional control of the hig toxin-antitoxin locus of antibiotic-resistance plasmid Rts1 from Proteus vulgaris

Pavelich, I. J.; Schureck, M. A.; Wang, D.; Hoffer, E. D.; Boamah, M.; Onouha, N.; Miles, S. J.; Okafor, C. D.; Dunham, C. M.

10.1101/2021.03.04.434028 — microbiology — Posted on 2021-03-05

4184 Localised expression of OsIAA29 suggests a key role for auxin in regulating development of the dorsal aleurone of early rice grains

Basunia, M. A.; Nonhebel, H. M.; Backhouse, D.; McMillan, M.

10.1101/2021.03.04.434009 — plant biology — Posted on 2021-03-05

4185 Universal gene co-expression network reveals receptor-like protein genes conferring broad-spectrum resistance in pepper (Capsicum annuum L.)

Kang, W.-H.; Lee, J.; Koo, N.; Kwon, J.-S.; Park, B.; Kim, Y.-M.; Yeom, S.-I.

10.1101/2021.03.04.433825 — plant biology — Posted on 2021-03-05

4186 Genotyping-by-sequencing-based identification of Arabidopsis pattern recognition receptor RLP32 recognizing proteobacterial translation initiation factor IF1

Fan, L.; Froehlich, K.; Melzer, E.; Albert, I.; Pruitt, R. N.; Zhang, L.; Albert, M.; Kim, S.-T.; Chae, E.; Weigel, D.; Gust, A. A.; Nuernberger, T.

10.1101/2021.03.04.433884 — plant biology — Posted on 2021-03-05

4187 Intraspecific variation in elemental accumulation and its association with salt tolerance in Paspalum vaginatum

Goad, D. M.; Kellogg, E. A.; Baxter, I.; Olsen, K. M.

10.1101/2021.03.04.433795 — plant biology — Posted on 2021-03-05

4188 In vivo homopropargylglycine incorporation enables nascent protein tagging, isolation and characterisation from Arabidopsis thaliana

Tivendale, N.; Fenske, R.; Duncan, O.; Millar, A. H.

10.1101/2021.03.04.433937 — plant biology — Posted on 2021-03-05

4189 An in-frame deletion mutation in the degron tail of auxin co-receptor IAA2 confers resistance to the herbicide 2,4-D in Sisymbrium orientale

Figueiredo, M. R. A.; Kuepper, A.; Malone, J. M.; Petrovic, T.; Figueiredo, A. B. T. B.; Campagnola, G.; Peersen, O. B.; Prasad, K. V. S. K.; Patterson, E. L.; Reddy, A. S. N.; Kubes, M. F.; Napier, R.; Preston, C.; Gaines, T. A.

10.1101/2021.03.04.433944 — plant biology — Posted on 2021-03-05

4190 Exogenous application of non-mature miRNA-encoded miPEP164c inhibits proanthocyanidin synthesis and stimulates anthocyanin accumulation in grape berry cells

Vale, M.; Rodrigues, J.; Badim, H.; Geros, H.; Conde, A.

10.1101/2021.03.04.433997 — plant biology — Posted on 2021-03-05

4191 Canopy Volume as a Tool for Early Detection of Plant Drought and Fertilization Stress: Banana plant fine-phenotype

Brook, A.; Tal, Y.; Markovich, O.; Rybnikova, N.

10.1101/2021.03.04.433868 — physiology — Posted on 2021-03-05

4192 Haplotype-aware variant calling enables high accuracy in nanopore long-reads using deep neural networks

Shafin, K.; Pesout, T.; Chang, P.-C.; Nattestad, M.; Kolesnikov, A.; Goel, S.; Baid, G.; Eizenga, J. M.; Miga, K. H.; Carnevali, P.; Jain, M.; Carroll, A.; Paten, B.

10.1101/2021.03.04.433952 — bioinformatics — Posted on 2021-03-05

4193 scCorr: A graph-based k-partitioning approach for single-cell gene-gene correlation analysis

Xu, H.; Hu, Y.; Zhang, X.; Aouizerat, B. E.; Yan, C.; Xu, K.

10.1101/2021.03.04.433945 — bioinformatics — Posted on 2021-03-05

4194 Large-scale placenta DNA methylation mega-analysis reveals fetal sex-specific differentially methylated CpG sites and regions

Andrews, S. V.; Yang, I. J.; Froehlich, K.; Oskotsky, T.; Sirota, M.

10.1101/2021.03.04.433985 — genomics — Posted on 2021-03-05

4195 Direct molecular evidence for an ancient, conserved developmental toolkit controlling post-transcriptional gene regulation in land plants

Jia, H.; Aadland, K.; Kolaczkowski, O.; Kolaczkowski, B.

10.1101/2021.03.04.433974 — evolutionary biology — Posted on 2021-03-05

4196 Large and interacting effects of temperature and nutrient addition on stratified microbial ecosystems in a small, replicated, and liquid dominated Winogradsky column approach

Suleiman, M.; Choffat, Y.; Daugaard, U.; Petchey, O. L.

10.1101/2020.12.09.415786 — microbiology — Posted on 2021-03-05

4197 Alternative splicing of auxiliary β2-subunits stabilizes Cav2.3 Ca2+ channel activity in continuously active midbrain dopamine neurons

Siller, A.; Hofer, N. T.; Tomagra, G.; Wiederspohn, N.; Hess, S.; Benkert, J.; Gaifullina, A.; Spaich, D.; Duda, J.; Poetschke, C.; Vilusic, K.; Fritz, E. M.; Schneider, T.; Kloppenburg, P.; Liss, B.; Carabelli, V.; Carbone, E.; Ortner, N. J.; Striessnig, J.

10.1101/2021.02.10.430224 — neuroscience — Posted on 2021-03-05

4198 Integrative multi-omics approach for stratification of tumor recurrence risk groups of Hepatocellular Carcinoma patients

Kaur, H.; Lathwal, A.; Raghava, G. P. S.

10.1101/2021.03.03.433841 — bioinformatics — Posted on 2021-03-05

4199 Deep learning image analysis for in vivo shortwave infrared imaging

Baulin, V.; Usson, Y.; Le Guevel, X.

10.1101/2021.03.04.433844 — cancer biology — Posted on 2021-03-04

4200 Evaluation of protein kinase D auto-phosphorylation as biomarker for NLRP3 inflammasome activation

Heiser, D.; Rubert, J.; Unterreiner, A.; Maurer, C.; Kamke, M.; Bodendorf, U.; Farady, C. J.; Roediger, B.; Bornancin, F.

10.1101/2021.03.04.433858 — cell biology — Posted on 2021-03-04

4201 The parathyroid hormone-dependent activation of osteoblasts enhances hematopoietic stem cell migration and reduces their engraftment abilities

Even, Y.; Yi, L.; Chang, C.-K.; Rossi, F. M.

10.1101/2021.03.04.433901 — cell biology — Posted on 2021-03-04

4202 Identifying Dihydropyrimidine Dehydrogenase as a Novel Regulator of Hepatic Steatosis

Sullivan, K. E.; Kumar, S.; Zhang, Y.; de Koning, E.; Yuan, J.; Fan, F.

10.1101/2021.03.04.433987 — cell biology — Posted on 2021-03-04

4203 After migration into blood circulation, hematopoietic stem cells can stably self-renew and maintain bone marrow while being skewed toward myeloid lineage when submitted to serial transplantation.

Even, Y.; Yi, L.; Chang, C.-K.; Rossi, F. M.

10.1101/2021.03.04.433880 — cell biology — Posted on 2021-03-04

4204 NuA4 and SAGA acetyltransferase complexes cooperate for repair of DNA breaks by homologous recombination

Cheng, X.; Cote, V.; Cote, J.

10.1101/2021.03.04.433861 — molecular biology — Posted on 2021-03-04

4205 Nonsterile immunity to cryptosporidiosis in infants is associated with mucosal IgA against the sporozoite and protection from malnutrition

Gilchrist, C. A.; Kabir, M.; Alam, M.; Nayak, U.; Anju, T.; Hossain, B.; Tarannum, R.; Khatun, A.; White, J.; Ma, J.; Haque, R.; Petri, W.

10.1101/2021.03.04.433864 — microbiology — Posted on 2021-03-04

4206 Basement membrane proteins as a substrate for efficient Trypanosoma brucei differentiation in vitro

Rojas, F.; Cayla, M.; Matthews, K.

10.1101/2021.03.04.433863 — microbiology — Posted on 2021-03-04

4207 Scoping review of the applications of peptide microarrays on the fight against human infections.

Vengesai, A.; Kasambala, M.; Mutandadzi, H.; Mduluza-Jokonya, T.; Mduluza, T.; Naicker, T.

10.1101/2021.03.04.433859 — immunology — Posted on 2021-03-04

4208 Mature parvalbumin interneuron function in prefrontal cortex requires activity during a postnatal sensitive period

Canetta, S. E.; Holt, E. S.; Benoit, L. J.; Teboul, E.; Ogden, R. T.; Harris, A. Z.; Kellendonk, C.

10.1101/2021.03.04.433943 — neuroscience — Posted on 2021-03-04

4209 Induction of Bdnf from promoter I following electroconvulsive seizures contributes to structural plasticity in neurons of the piriform cortex

Ramnauth, A. D.; Maynard, K.; Kardian, A. S.; Phan, B. N.; Tippani, M.; Rajpurohit, S.; Hobbs, J. W.; Page, S. C.; Jaffe, A. E.; Martinowich, K.

10.1101/2021.03.04.433962 — neuroscience — Posted on 2021-03-04

4210 Non-coding enhancer RNA regulates NPAS4 in the mPFC to control chronic stress-induced anhedonia-like behavior

Hughes, B. W.; Siemsen, B. M.; Berto, S.; Kumar, J.; Cornbrooks, R. G.; Akiki, R. M.; Carter, J. S.; Brase, E. C.; Koike, N.; Scofield, M. D.; Cowan, C. W.; Taniguchi, M.

10.1101/2021.03.04.433930 — neuroscience — Posted on 2021-03-04

4211 Kaolinite deposits in the upper Iguacu river, Brazil: formation and mineralogical attributes

Ferreira, D. N.; Melo, V. d. F.; Vidal-Torrado, P.; Oliveira, J. C.

10.1101/2021.03.04.433860 — scientific communication and education — Posted on 2021-03-04

4212 Young chicks rely on perceptual grouping to discriminate prime numbers

Loconsole, M.; De Agro, M.; Regolin, L.

10.1101/2021.03.04.433923 — animal behavior and cognition — Posted on 2021-03-04

4213 Homothorax Controls a Binary Rhodopsin Switch in Drosophila Ocelli

Mishra, A. K.; Fritsch, C.; Voutev, R.; Mann, R. S.; Sprecher, S. G.

10.1101/2021.03.04.433862 — genetics — Posted on 2021-03-04

4214 Identification and predictability of soil quality factors and indicators from conventional soil and vegetation classifications

Simfukwe, P.; Hill, P. W.; Jones, D. L.; Emmett, B.; on those listed above,

10.1101/2021.03.04.433857 — ecology — Posted on 2021-03-04

4215 Generation and mutational analysis of a transgenic mouse model of human SRY

Thomson, E.; Zhao, L.; Chen, Y.-S.; Longmuss, E.; Ng, E. T.; Sreenivasan, R.; Croft, B.; Song, X.; Sinclair, A.; Weiss, M.; Pelosi, E.; Koopman, P.

10.1101/2021.03.04.433906 — developmental biology — Posted on 2021-03-04

4216 A novel, anatomy-similar in vitro model of 3D airway epithelial for anti-coronavirus drug discovery

Zhang, Y.; Ma, D.; Zhang, J. D.; Liu, X.; Zhu, Q.; Wang, L.; Gao, L.

10.1101/2021.03.03.433824 — microbiology — Posted on 2021-03-04

4217 Characterization of the Chlamydomonas reinhardtii phycosphere reveals conserved features of the plant microbiota

Duran, P.; Flores-Uribe, J.; Wippel, K.; Zhang, P.; Guan, R.; Garrido-Oter, R.

10.1101/2021.03.04.433956 — microbiology — Posted on 2021-03-04

4218 Killing of Gram-negative and Gram-positive bacteria by a bifunctional cell wall-targeting T6SS effector

Le, N.-H.; Pinedo, V.; Lopez, J.; Cava, F.; Feldman, M. F.

10.1101/2021.03.04.433973 — microbiology — Posted on 2021-03-04

4219 Multimeric nanobodies from camelid engineered mice and llamas potently neutralize SARS-CoV-2 variants

Xu, J.; Xu, K.; Jung, S. K.; Conte, A.; Lieberman, J.; Muecksch, F.; Lorenzi, J. C. C.; Park, S.; Wang, Z.; Tessarollo, L.; Bylund, T.; Chuang, G.-Y.; Olia, A.; Teng, I.-T.; Zhou, T.; Stephens, T.; Tsybovsky, Y.; Bieniasz, P. D.; Hatziioannou, T.; Nussenzweig, M.; Kwong, P.; Casellas, R.

10.1101/2021.03.04.433768 — immunology — Posted on 2021-03-04

4220 The hippocampus shows an own-age bias during unfamiliar face viewing

Koen, J. D.; Hauck, N.; Rugg, M. D.

10.1101/2021.02.15.431110 — neuroscience — Posted on 2021-03-04

4221 The planning horizon for movement sequences

Ariani, G.; Kordjazi, N.; Pruszynski, J. A.; Diedrichsen, J.

10.1101/2020.07.15.204529 — neuroscience — Posted on 2021-03-04

4222 Mechanisms Underlying Economic Revealed Preference Of Multi-Component Bundles In Primate Orbitofrontal Cortex

Pastor-Bernier, A.; Schultz, W.

10.1101/2021.03.02.433629 — neuroscience — Posted on 2021-03-04

4223 Insights into the susceptibility of rice to a floral disease

Li, G.-B.; Fan, J.; Liu, J.; Wu, J.-L.; Hu, X.-H.; He, J.-X.; Shen, S.; Wang, H.; Zhu, Y.; He, F.; Gao, H.; Gishkori, Z. G. N.; Zhao, J.-H.; Li, Y.; Huang, F.; Huang, Y.-Y.; Zhao, Z.-X.; Zhang, J.-W.; Zhou, S.-X.; Pu, M.; Chen, X.; Wang, J.; Li, W.; Wu, X.-J.; Ning, Y.; Sun, W.; Wang, W.-M.

10.1101/2021.03.03.433744 — plant biology — Posted on 2021-03-04

4224 The M1 aminopeptidase NPEPPS is a novel regulator of cisplatin sensitivity

10.1101/2021.03.04.433676 — cancer biology — Posted on 2021-03-04

4225 Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma

Ohmura, S.; Marchetto, A.; Orth, M. F.; Li, J.; Jabar, S.; Ranft, A.; Vinca, E.; Ceranski, K.; Carreno-Gonzalez, M. J.; Romero-Perez, L.; Wehweck, F. S.; Musa, J.; Bestvater, F.; Knott, M. M. L.; Hoelting, T. L. B.; Hartmann, W.; Dirksen, U.; Kirchner, T.; Cidre-Aranaz, F.; Grunewald, T. G. P.

10.1101/2021.03.04.433896 — cancer biology — Posted on 2021-03-04

4226 NKX2-1 controls lung cancer progression by inducing DUSP6 to dampen ERK activity

Ingram, K.; Samson, S. C.; Zewdu, R.; Zitnay, R. G.; Snyder, E. L.; Mendoza, M. C.

10.1101/2021.03.04.433941 — cancer biology — Posted on 2021-03-04

4227 Self-organization of Tissue Growth by Interfacial Mechanical Interactions in Multi-layered Systems

Chen, T.; Zhao, Y.; Zhao, X.; Li, S.; Cao, J.; Du, J.; Cao, Y.; Fan, Y.

10.1101/2021.03.04.433890 — biophysics — Posted on 2021-03-04

4228 Mechanical Interplay Between Transcription Elongation and DNA Supercoiling

Tripathi, S.; Brahmachari, S.; Onuchic, J. N.; Levine, H.

10.1101/2021.03.04.433986 — biophysics — Posted on 2021-03-04

4229 Published Anti-SARS-CoV-2 In Vitro Hits Share Common Mechanisms of Action that Synergize with Antivirals

Xing, J.; Paithankar, S.; Liu, K.; Uhl, K.; Li, X.; Ko, M.; Kim, S.; Haskins, J.; Chen, B.

10.1101/2021.03.04.433931 — bioinformatics — Posted on 2021-03-04

4230 YieldNet: A Convolutional Neural Network for Simultaneous Corn and Soybean Yield Prediction Based on Remote Sensing Data

Khaki, S.; Pham, H.; Wang, L.

10.1101/2020.12.05.413203 — bioinformatics — Posted on 2021-03-04

4231 Label-retention expansion microscopy

Shi, X.; Li, Q.; Dai, Z.; Tran, A. A.; Feng, S.; Ramirez, A. D.; Lin, Z.; Wang, X.; Chow, T. T.; Chen, J.; Kumar, D.; McColloch, A. R.; Reiter, J. F.; Huang, E. J.; Seiple, I. B.; Huang, B.

10.1101/687954 — bioengineering — Posted on 2021-03-04

4232 Effect of Pre-harvest Calcium Chloride and Salicylic Acid Spray on Morphological and Biochemical Traits of Guava (Psidium guajava)

Kaushik, L.; Kumar, R.; Reddy, D. K.; Kaushik, P.

10.1101/2021.03.04.433865 — biochemistry — Posted on 2021-03-04

4233 The contributions from the progenitor genomes of the mesopolyploid Brassiceae are evolutionarily distinct but functionally compatible

Hao, Y.; Mabry, M. E.; Edger, P.; Freeling, M.; Zheng, C.; Jin, L.; VanBuren, R.; Colle, M.; An, H.; Abrahams, R. S.; Washburn, J. D.; Qi, X.; Barry, K.; Daum, C.; Shu, S.; Schmutz, J.; Sankoff, D.; Barker, M. S.; Lyons, E.; Pires, J. C.; Conant, G. C.

10.1101/2020.08.10.245258 — genomics — Posted on 2021-03-04

4234 Human cells contain myriad excised linear introns with potential functions in gene regulation and as RNA biomarkers

Yao, J.; Xu, H.; Winans, S.; Wu, D. C.; Ares, M.; Lambowitz, A. M.

10.1101/2020.09.07.285114 — genomics — Posted on 2021-03-04

4235 Detection of ESKAPE pathogens and Clostridioides difficile in Simulated Skin Transmission Events with Metagenomic and Metatranscriptomic Sequencing

Ternus, K. L.; Keplinger, N. C.; Kappell, A. D.; Godbold, G. D.; Palsikar, V.; Acevedo, C. A.; Weber, K. L.; LeSassier, D. S.; Schulte, K. Q.; Westfall, N. M.; Hewitt, F. C.

10.1101/2021.03.04.433847 — genomics — Posted on 2021-03-04

4236 The genetics of gene expression in a C. elegans multi parental recombinant inbred line population.

Snoek, B. L.; Sterken, M. G.; Nijveen, H.; Volkers, R. J.; Riksen, J.; Rosenstiel, P.; Schulenburg, H.; Kammenga, J.

10.1101/2021.03.04.433879 — genetics — Posted on 2021-03-04

4237 Locus specific epigenetic modalities of random allelic expression imbalance

Marion-Poll, L.; Foret, B.; Zielinski, D.; Massip, F.; Attia, M.; Carter, A. C.; Syx, L.; Chang, H. Y.; Gendrel, A.-V.; Heard, E.

10.1101/2021.03.04.433808 — molecular biology — Posted on 2021-03-04

4238 Stimulation of adaptive gene amplification by origin firing under replication fork constraint

Whale, A. J.; King, M.; Hull, R. M.; Krueger, F.; Houseley, J.

10.1101/2021.03.04.433911 — molecular biology — Posted on 2021-03-04

4239 Circular RNAs exhibit limited evidence for translation, or translation regulation of the mRNA-counterpart in terminal hematopoiesis

Nicolet, B. P.; Jansen, S.; Heideveld, E.; Ouwehand, W. h.; Van den akker, E.; von lindern, M. M.; Wolkers, M. C.

10.1101/2020.10.22.348276 — molecular biology — Posted on 2021-03-04

4240 The Borrelia burgdorferi adenylyl cyclase, CyaB, is important for virulence factor production and mammalian infection

Ante, V. M.; Farris, L. C.; Saputra, E. P.; Hall, A. J.; O'Bier, N. S.; Olivia Chavez, A. S.; Marconi, R. C.; Lybecker, M. C.; Hyde, J. A.

10.1101/2021.03.04.433918 — microbiology — Posted on 2021-03-04

4241 Salmonella Typhimurium outer membrane protein A (OmpA) renders protection against nitrosative stress by promoting SCV stability in murine macrophages

Roy Chowdhury, A.; Sah, S.; Varshney, U.; Chakravortty, D.

10.1101/2021.02.12.430987 — microbiology — Posted on 2021-03-04

4242 Paucimyces polynucleatus gen. nov, sp. nov., a novel polycentric genus of anaerobic gut fungi from the feces of a wild blackbuck antelope

Hanafy, R. A.; Youssef, N. H.; Elshahed, M.

10.1101/2021.03.04.433954 — microbiology — Posted on 2021-03-04

4243 Disinfection of SARS-CoV-2 contaminated surfaces of personal items with UVC-LED disinfection boxes

Bormann, M.; Alt, M.; Schipper, L.; van de Sand, L.; Otte, M.; Meister, T. L.; Dittmer, U.; Witzke, O.; Steinmann, E.; Krawczyk, A.

10.1101/2021.03.03.433725 — microbiology — Posted on 2021-03-04

4244 Three PilZ domain proteins, PlpA, PixA and PixB, have distinct functions in regulation of motility and development in Myxococcus xanthus

Kuzmich, S.; Skotnicka, D.; Szadkowski, D.; Klos, P.; Perez-Burgos, M.; Schander, E.; Schumacher, D.; Sogaard-Andersen, L.

10.1101/2021.03.04.433885 — microbiology — Posted on 2021-03-04

4245 Combination of in vivo phage therapy data with in silico model highlights key parameters for treatment efficacy

Delattre, R.; Seurat, J.; Haddad, F.; Nguyen, T.-T.; Gaborieau, B.; Kane, R.; Dufour, N.; Ricard, J.-D.; Guedj, J.; Debarbieux, L.

10.1101/2021.03.04.433924 — microbiology — Posted on 2021-03-04

4246 Identification of gene products involved in plant colonization by Pantoea sp. YR343 using a diguanylate cyclase expressed in the presence of plants

Bible, A. N.; Chang, M.; Morrell-Falvey, J. L.

10.1101/2021.03.03.433726 — microbiology — Posted on 2021-03-04

4247 The memory B cell response to influenza vaccination is impaired in older persons

Carr, E. J.; Wheatley, A. K.; Hill, D. L.; Linterman, M. A.

10.1101/2021.03.04.433942 — immunology — Posted on 2021-03-04

4248 Accounting for B cell behaviour and sampling bias yields a superior predictor of anti-PD-L1 response in bladder cancer

Dyugay, I. A.; Lukyanov, D. K.; Turchaninova, M. A.; Zaretsky, A. R.; Khalmurzaev, O. A.; Matveev, V. B.; Shugay, M. M.; Shelyakin, P. V.; Chudakov, D. M.

10.1101/2021.03.04.433370 — immunology — Posted on 2021-03-04

4249 T-cell Repertoire Characteristics of Asymptomatic and Re-detectable Positive COVID-19 Patients

Xu, J.; Shi, Y.; Wang, Y.; Liu, Y.; Lin, D.; Zhang, J.; Lin, J.; Hu, W.; He, H.; Wang, W.; Fan, W.; Li, L.; Lan, H.; Lei, C.; Wang, K.; Wang, D.

10.1101/2021.03.03.433579 — immunology — Posted on 2021-03-04

4250 UBXN3B Restricts Viral Pathogenesis by Maintaining Hematopoietic Homeostasis

WANG, P.; Geng, T.; Yang, D.; Lin, T.; Harrison, A.; Haynes, L.; Torrance, B.; Wang, B.; Vella, A. T.; Cheng, G.; Fikrig, E.; Yang, L.

10.1101/2021.03.04.433919 — immunology — Posted on 2021-03-04

4251 Ex vivo mass cytometry analysis reveals a profound myeloid proinflammatory signature in psoriatic arthritis synovial fluid

Yager, N.; Cole, S.; Lledo Lara, A.; Maroof, A.; Penkava, F.; Knight, J.; Bowness, P.; Al-Mossawi, H.

10.1101/2021.03.04.433903 — immunology — Posted on 2021-03-04

4252 High and low expression of the hyperpolarization activated current (Ih) in mouse CA1 stratum oriens interneurons.

Hewitt, L. T.; Ordemann, G. J.; Brager, D. H.

10.1101/2021.02.26.433114 — neuroscience — Posted on 2021-03-04

4253 Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling

Vasavda, C.; Semenza, E. R.; Liew, J.; Kothari, R.; Dhindsa, R. S.; Shanmukha, S.; Ricco, C.; Tokhunts, R.; Snowman, A. M.; Albacarys, L. K.; Paul, B. D.; Snyder, S. H.

10.1101/2020.12.01.405720 — neuroscience — Posted on 2021-03-04

4254 Dendritic signal integration in a Drosophila Mushroom Body Output Neuron (MBON) essential for learning and memory

Hafez, O.; Escribano, B.; Ziegler, R.; Hirtz, J. J.; Niebur, E.; Pielage, J.

10.1101/2020.12.06.413500 — neuroscience — Posted on 2021-03-04

4255 A Structured Professional Development Curriculum for Postdoctoral Fellows Leads to Recognized Knowledge Growth

Steen, K.; Vornhagen, J.; Weinberg, Z. Y.; Boulanger-Bertolus, J.; Rao, A.; Gardner, M. E.; Subramanian, S.

10.1101/2020.10.15.340059 — scientific communication and education — Posted on 2021-03-04

4256 The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of Acute Myeloid Leukemias

Paolillo, R.; Boulanger, M.; Gatel, P.; Gabellier, L.; Tempe, D.; Hallal, R.; De Toledo, M.; Moreaux, J.; Baik, H.; Gueret, E.; Recher, C.; Sarry, J.-E.; Cartron, G.; Piechaczyk, M.; Bossis, G.

10.1101/2021.03.04.433871 — cancer biology — Posted on 2021-03-04

4257 Slow, heterogeneous NFκB single molecule conformational dynamics and implications for function

Chen, W.; Liu, W.; Wolynes, P.; Komives, E. A.

10.1101/2021.03.02.433616 — biophysics — Posted on 2021-03-04

4258 Diffusion barriers and adaptive carbon uptake strategies enhance the modeled performance of the algal CO2-concentrating mechanism

Fei, C.; Wilson, A. T.; Mangan, N. M.; Wingreen, N. S.; Jonikas, M. C.

10.1101/2021.03.04.433933 — biophysics — Posted on 2021-03-04

4259 A novel conformational state for SARS-CoV-2 main protease

Fornasier, E.; Macchia, M. L.; Giachin, G.; Sosic, A.; Pavan, M.; Sturlese, M.; Salata, C.; Moro, S.; Gatto, B.; Bellanda, M.; Battistutta, R.

10.1101/2021.03.04.433882 — biochemistry — Posted on 2021-03-04

4260 Structural insights into plasticity and discovery of remdesivir metabolite GS-441524 binding in SARS-CoV-2 macrodomain

Ni, X.; Schroeder, M.; Olieric, V.; Sharpe, M. E.; Olmos, V.; Proschak, E.; Merk, D.; Knapp, S.; Chaikuad, A.

10.1101/2021.03.04.433966 — biochemistry — Posted on 2021-03-04

4261 Sod1 Integrates Oxygen Availability to Redox Regulate NADPH Production and the Thiol Redoxome

Montllor-Albalate, C.; Kim, H.; Jonke, A. P.; Torres, M. P.; Reddi, A.

10.1101/2021.03.04.433951 — biochemistry — Posted on 2021-03-04

4262 Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes.

Seyres, D.; Cabassi, A.; Lambourne, J. J.; Burden, F.; Farrow, S.; McKinney, H.; Batista, J.; Kempster, C.; Pietzner, M.; Slingsby, O.; Cao, T. H.; Quinn, P.; Stefanucci, L.; Sims, M. C.; Rehnstrom, K.; Adams, C.; Frary, A.; Erguener, B.; Kreuzhuber, R.; Mocciaro, G.; Allison, M.; D'Amore, S.; Koulman, A.; Grassi, L.; Griffin, J. L.; Ng, L. L.; Park, A.; Savage, D. B.; Langenberg, C.; Wareham, N. J.; Bock, C.; Downes, K.; Vacca, M.; Kirk, P. D.; Frontini, M.

10.1101/2020.03.06.961805 — genomics — Posted on 2021-03-04

4263 Reverse plasticity underlies rapid evolution by clonal selection within populations of fibroblastspropagated on a novel soft substrate

Purkayastha, P.; Pendyala, K.; Saxena, A. S.; Hakimjavadi, H.; Chamala, S.; Dixit, P. D.; Baer, C. F.; Lele, T. P.

10.1101/2020.04.26.061911 — evolutionary biology — Posted on 2021-03-04

4264 An "individualist" model of an active genome in a developing embryo

Huang, S.-K.; Dutta, S.; Whitney, P. H.; Shvartsman, S. Y.; Rushlow, C. A.

10.1101/2021.01.08.425929 — developmental biology — Posted on 2021-03-04

4265 Misoprostol Treatment Prevents Hypoxia-Induced Cardiac Dysfunction, Aberrant Cardiomyocyte Mitochondrial Dynamics and Permeability Transition Through Bnip3 Phosphorylation

Martens, M. D.; Seshadri, N.; Nguyen, L.; Chapman, D.; Hensen, E. S.; Xiang, B.; Falk, L.; Mendoza, A.; Rattan, S.; Gibson, S. B.; Keijzer, R.; Saleem, A. D.; Hatch, G. M.; Doucette, C. A.; Karch, J. M.; Dolinsky, V. W.; Dixon, I. M.; West, A. R.; Rampitsch, C.; Gordon, J. W.

10.1101/2020.10.09.333666 — cell biology — Posted on 2021-03-04

4266 Inhibiting SARS-CoV-2 infection in vitro by suppressing its receptor, angiotensin-converting enzyme 2, via aryl-hydrocarbon receptor signal

Tanimoto, K.; Hirota, K.; Fukazawa, T.; Matsuo, Y.; Nomura, T.; Tanuza, N.; Hirohashi, N.; Bono, H.; Sakakuchi, T.

10.1101/2021.03.04.433658 — molecular biology — Posted on 2021-03-04

4267 5' Modifications Improve Potency and Efficacy of DNA Donors for Precision Genome Editing

Ghanta, K. S.; Chen, Z.; Mir, A.; Dokshin, G. A.; Krishnamurthy, P. M.; Yoon, Y.; Gallant, J.; Xu, P.; Zhang, X.-O.; Ozturk, A.; Shin, M.; Idrizi, F.; Liu, P.; Gneid, H.; Lawson, N. D.; Rivera-Perez, J. A.; Sontheimer, E. J.; Watts, J. K.; Mello, C. C.

10.1101/354480 — molecular biology — Posted on 2021-03-04

4268 Efficient Inhibition of SARS-CoV-2 Using Chimeric Antisense Oligonucleotides through RNase L Activation

Su, X.; Ma, W.; Cheng, B.; Wang, Q.; Guo, Z.; Zhou, D.; Tang, X.

10.1101/2021.03.04.433849 — microbiology — Posted on 2021-03-04

4269 SARS-CoV-2 viability in time on experimental surfaces

Nikiforova, M.; Siniavin, A.; Shidlovskaya, E.; Kuznetsova, N.; Gushchin, V.

10.1101/2021.03.04.433846 — microbiology — Posted on 2021-03-04

4270 The mRNA-LNP platform's lipid nanoparticle component used in preclinical vaccine studies is highly inflammatory

Ndeupen, S.; Qin, Z.; Jacobsen, S.; Gibb, M.; Estanbouli, H.; Bouteau, A.; Cardenas, J.; Uthra, B.; Wang, Y.; Gu, J.; Igyarto, B. Z.

10.1101/2021.03.04.430128 — immunology — Posted on 2021-03-04

4271 SARS-CoV-2 variant with higher affinity to ACE2 shows reduced sera neutralization susceptibility

Vogel, M.; Chang, X.; Sousa Augusto, G.; Mohsen, M. O.; Speiser, D. E.; Bachmann, M. F.

10.1101/2021.03.04.433887 — immunology — Posted on 2021-03-04

4272 Optimization of an LNP-mRNA vaccine candidate targeting SARS-CoV-2 receptor-binding domain

Kobiyama, K.; Imai, M.; Jounai, N.; Nakayama, M.; Hioki, K.; Iwatsuki-Horimoto, K.; Yamayoshi, S.; Tsuchida, J.; Niwa, T.; Suzuki, T.; Ito, M.; Yamada, S.; Watanabe, T.; Kiso, M.; Negishi, H.; Temizoz, B.; Ishigaki, H.; Kitagawa, Y.; Nguyen, C. T.; Itoh, Y.; Takeshita, F.; Kawaoka, Y.; Ishii, K. J.

10.1101/2021.03.04.433852 — immunology — Posted on 2021-03-04

4273 Neural representation of abstract task structure during generalization

Vaidya, A. R.; Jones, H. M.; Castillo, J.; Badre, D.

10.1101/2020.07.21.213009 — neuroscience — Posted on 2021-03-04

4274 Increased fronto-temporal connectivity by modified melody in real music

Kim, C. H.; Seol, J.; Jin, S.-H.; Kim, J. S.; Kim, Y.; Yi, S. W.; Chung, C. K.

10.1101/2020.01.12.903609 — neuroscience — Posted on 2021-03-04

4275 CaSR modulates sodium channel-mediated Ca 2+ -dependent excitability

Martiszus, B. J.; Tsintsadze, T.; Chang, W.; Smith, S. M.

10.1101/2021.03.03.433701 — neuroscience — Posted on 2021-03-04

4276 Ion channel expression and electrophysiology of singular human (primary and induced pluripotent stem cell derived) cardiomyocytes

Schmid, C.; Abi-Gerges, N.; Zellner, D.; Rast, G.

10.1101/2021.03.04.433834 — pharmacology and toxicology — Posted on 2021-03-04

4277 Identification and characterization of novel plasma proteins in drug resistant HIV/AIDS patients by SWATH-MS

Barik, S. K.; Tripathy, S. P.; Bisht, D. K.; Singh, P.; Chakraborty, R.; Chadar, M. K.; Patil, S. A.; Singh, T. P.; Tandon, R.; Jena, S.; Mohanty, K. K.

10.1101/2021.03.04.433855 — biochemistry — Posted on 2021-03-04

4278 Barcode Sequencing and a High-throughput Assay for Chronological Lifespan Uncover Ageing-associated Genes in Fission Yeast

Romila, C.; Townsend, S.; Malecki, M.; Kamrad, S.; Rodriguez-Lopez, M.; Hillson, O.; Cotobal, C.; Ralser, M.; Bahler, J.

10.1101/2021.03.04.433786 — genomics — Posted on 2021-03-04

4279 Laboratory Yeast Strains Rely On Oxidative Phosphorylation For Efficient ATP Production

Moharir, A.; Gay, L.; Babst, M.

10.1101/2021.03.03.433835 — microbiology — Posted on 2021-03-04

4280 Mechanistic insights into the success of xenobiotic degraders resolved from metagenomes of microbial enrichment cultures

Li, J.; Jia, C.; Lu, Q.; Hungate, B. A.; Dijkstra, P.; Wang, S.; Wu, C.; Chen, S.; Li, D.; Shim, H.

10.1101/2021.03.03.433815 — microbiology — Posted on 2021-03-04

4281 A Self-Replicating Radiation-Shield for Human Deep-Space Exploration: Radiotrophic Fungi can Attenuate Ionizing Radiation aboard the International Space Station

Shunk, G. K.; Gomez, X. R.; Averesch, N. J. H.

10.1101/2020.07.16.205534 — microbiology — Posted on 2021-03-04

4282 Lipid production from Zygosaccharomyces siamensis AP1 using glycerol as a carbon source

Ilmi, M.; Siswantoro, M.

10.1101/2021.03.03.433823 — microbiology — Posted on 2021-03-04

4283 Inhibition of CDK4/6 Overcomes Primary Resistance to PD-1 Blockade in Malignant Mesothelioma

Jang, H.-J.; Truong, C. Y.; Lo, E. M.; Holmes, H. M.; Ramos, D.; Ramineni, M.; Lee, J.-S.; Wang, D. Y.; Pietropaolo, M.; Ripley, R. T.; Burt, B.; Lee, H.-S.

10.1101/2021.03.04.432811 — immunology — Posted on 2021-03-04

4284 Pro-inflammatory alveolar macrophages associated with allograft dysfunction after lung transplantation

Moshkelgosha, S.; Wilson,, G. W.; Duong, A.; Andrews, T. S.; Renaud, B.; Berra, G.; Liu, M.; Keshavjee, S.; Martinu, T.; MacParland, S.; Yeung, J.; Juvet, S. C.

10.1101/2021.03.03.433654 — immunology — Posted on 2021-03-04

4285 Suppression of PIK3CA-driven epileptiform activity by acute pathway control

Roy, A.; Han, V. Z.; Bard, A. M.; Wehle, D. T.; Smith, S. E. P.; Ramirez, J.-M.; Kalume, F.; Millen, K. J.

10.1101/2021.03.03.433821 — neuroscience — Posted on 2021-03-04

4286 Development of Large-Scale Brain Network Dynamics in Children

Lei, T.; Liao, X.; Chen, X.; Zhao, T.; Xu, Y.; Xia, M.; Zhang, J.; Sun, X.; Wei, Y.; Men, W.; Wang, Y.; Hu, M.; Zhao, G.; Du, B.; Wu, Q.; Tan, S.; Gao, J.; Qin, S.; Tao, S.; Dong, Q.; He, Y.

10.1101/2021.03.03.433828 — neuroscience — Posted on 2021-03-04

4287 Experimental tests of functional molecular regeneration via a standard framework for coordinating synthetic cell building

Wei, E.; Endy, D.

10.1101/2021.03.03.433818 — synthetic biology — Posted on 2021-03-04

4288 A low sugar diet enhances Drosophila body size in males and females via sex-specific mechanisms

Millington, J. W.; Wat, L. W.; Sun, Z.; Basner-Collins, P. J.; Brownrigg, G. P.; Rideout, E. J.

10.1101/2021.03.03.433819 — physiology — Posted on 2021-03-04

4289 Viscosity of fluid membranes measured from vesicle deformation

Faizi, H. A.; Dimova, R.; Vlahovska, P.

10.1101/2021.03.04.433848 — biophysics — Posted on 2021-03-04

4290 Mass Dynamics 1.0: A streamlined, web-based environment for analyzing, sharing and integrating Label-Free Data.

Bloom, J. I.; Triantafyllidis, A.; Burton, P.; Infusini, G.; Webb, A. I.

10.1101/2021.03.03.433806 — bioinformatics — Posted on 2021-03-04

4291 riboCIRC: a comprehensive database of translatable circRNAs

Li, H.; Xie, M.; Wang, Y.; Yang, L.; Xie, Z.; Wang, H.

10.1101/2021.03.03.433665 — bioinformatics — Posted on 2021-03-04

4292 Proteomic analysis identifies novel binding partners of BAP1

Baas, R.; van der Wal, F. J.; Bleijerveld, O. B.; van Attikum, H.; Sixma, T. K.

10.1101/2021.03.03.433804 — biochemistry — Posted on 2021-03-04

4293 Nemertean, brachiopod and phoronid neuropeptidomics reveals ancestral spiralian signalling systems

Thiel, D.; Yanez Guerra, L. A.; Franz-Wachtel, M.; Hejnol, A.; Jekely, G.

10.1101/2021.03.03.433790 — evolutionary biology — Posted on 2021-03-04

4294 The analysis of epigenomic evolution

Sahm, A.; Koch, P.; Horvath, S.; Hoffmann, S.

10.1101/2021.03.03.433796 — evolutionary biology — Posted on 2021-03-04

4295 Present and Future Ecological Niche Modeling of Rift Valley fever in East Africa in Response to Climate Change

Muema, C.; Ngarega, B. K.; Muturi, E.; Wei, H.; Yang, H.

10.1101/2021.03.03.433832 — ecology — Posted on 2021-03-04

4296 Identification of a fully dechlorinated product of chlordecone in soil microcosms and enrichment cultures

Lomheim, L.; Flick, R.; Rambinaising, S.; Gaspard, S.; Edwards, E. A.

10.1101/2021.03.03.433826 — microbiology — Posted on 2021-03-04

4297 Novel Paju Apodemus Paramyxovirus 1 and 2, Harbored by Apodemus agrarius in The Republic of Korea

Lee, S.-H.; No, J. S.; Kim, K.; Budhathoki, S.; Park, K.; Lee, G. Y.; Cho, S.; Choi, H. S.; Kim, B.-H.; Cho, S.; Kim, J. W.; Lee, J. G.; Cho, S. H.; Kim, H.-C.; Klein, T. A.; Uhm, C.-S.; Kim, W.-K.; Song, J.-W.

10.1101/2021.03.03.433816 — microbiology — Posted on 2021-03-04

4298 Toxigenic Profile of Clostridium perfringens Strains Isolated from Natural Ingredient Laboratory Animal Diets

Johnston, M. D.; Whiteside, T. E.; Williamson, M. E.; Kurtz, D. M.

10.1101/2021.03.03.433836 — microbiology — Posted on 2021-03-04

4299 Laminar-specific functional connectivity mapping with multi-slice line-scanning fMRI

Choi, S.; Zeng, H.; Chen, Y.; Sobczak, F.; Qian, C.; Yu, X.

10.1101/2021.03.03.433376 — neuroscience — Posted on 2021-03-04

4300 A deep learning algorithm for 3D cell detection in whole mouse brain image datasets

Tyson, A. L.; Rousseau, C. V.; Niedworok, C. J.; Keshavarzi, S.; Tsitoura, C.; Cossell, L.; Strom, M.; Margrie, T. W.

10.1101/2020.10.21.348771 — neuroscience — Posted on 2021-03-04

4301 LncRNA analyses reveal increased levels of non-coding centromeric transcripts in hepatocellular carcinoma

Necsulea, A.; Veber, P.; Boldanova, T.; Ng, C. K.; Wieland, S.; Heim, M. H.

10.1101/2021.03.03.433778 — cancer biology — Posted on 2021-03-04

4302 Understanding conformational dynamics from macromolecular crystal diffuse scattering

Mazumder, P.; Ayyer, K.

10.1101/2021.02.11.429988 — biophysics — Posted on 2021-03-04

4303 Integrative multi-omics approach for stratification of tumor recurrence risk groups of Hepatocellular Carcinoma patients

Kaur, H.; Raghava, G. P. S.; Lathwal, A.

10.1101/2021.03.03.433841 — bioinformatics — Posted on 2021-03-04

4304 On the effect of phylogenetic correlations in coevolution-based contact prediction in proteins

Rodriguez Horta, E.; Weigt, M.

10.1101/2020.08.12.247577 — bioinformatics — Posted on 2021-03-04

4305 Comparative evaluation of plasma protein purification and 2-D gel electrophoresis protocols for analysis of HIV-1 infected human plasma proteins

Barik, S. K.; Barik, D. K.; Mohanty, K. K.; Bisht, D.; Patil, S. A.; Singh, R.; Sharma, D. K.; Tripathy, S. P.; Tandon, R.; Singh, T. P.; Jena, S.

10.1101/2021.03.03.433830 — biochemistry — Posted on 2021-03-04

4306 Characterising ontogeny of numerosity discrimination in zebrafish reveals the use of multiple, numerical and non- numerical mechanisms.

Sheardown, E.; Torres-Perez, J. V.; Anagianni, S.; Fraser, S.; Vallortigara, G.; Butterworth, B.; Miletto-Petrazzini, M. E.; Brennan, C. H.

10.1101/2021.02.25.432846 — animal behavior and cognition — Posted on 2021-03-04

4307 Altered Subgenomic RNA Expression in SARS-CoV-2 B.1.1.7 Infections

Parker, M. D.; Lindsey, B. B.; Shah, D. R.; Hsu, S.; Keeley, A. J.; Partridge, D. G.; Leary, S.; Cope, A.; State, A.; Johnson, K.; Ali, N.; Raghei, R.; Heffer, J.; Smith, N.; Zhang, P.; Gallis, M.; Louka, S. F.; Hornsby, H. R.; Whiteley, M.; Foulkes, B. H.; Christou, S.; Wolverson, P.; Pohare, M.; Hansford, S. E.; Green, L. R.; Evans, C.; Raza, M.; Wang, D.; Gaudieri, S.; Mallal, S.; The COVID-19 Genomics UK (COG-UK) consortium, ; de Silva, T. I.

10.1101/2021.03.02.433156 — genomics — Posted on 2021-03-04

4308 An updated assembly strategy helps parsing the cryptic mitochondrial genome evolution in plants

Feng, Y.; Xiang, X.; Fu, Z.; Pan, R.; Jin, X.

10.1101/2021.03.02.433321 — evolutionary biology — Posted on 2021-03-04

4309 Topoisomerase 1 dependent R-loop deficiency drives accelerated replication and genomic instability

Sarni, D.; Shtrikman, A.; Oren, Y. S.; Kerem, B.

10.1101/2020.07.21.214700 — cell biology — Posted on 2021-03-04

4310 SARS-CoV-2 Variants Reveal Features Critical for Replication in Primary Human Cells

Pohl, M. O.; Busnadiego, I.; Kufner, V.; Glas, I.; Karakus, U.; Schmutz, S.; Zaheri, M.; Abela, I.; Trkola, A.; Huber, M.; Stertz, S.; Hale, B. G.

10.1101/2020.10.22.350207 — microbiology — Posted on 2021-03-04

4311 Kin discrimination promotes horizontal gene transfer between unrelated strains in Bacillus subtilis

Stefanic, P.; Belcijan, K.; Kraigher, B.; Kostanjsek, R.; Nesme, J.; Madsen, j.; Kovac, J.; Sorensen, S. J.; Vos, M.; Mandic-Mulec, I.

10.1101/756569 — microbiology — Posted on 2021-03-04

4312 A machine learning approach for detecting vicarious trial and error behaviors

Miles, J. T.; Kidder, K. S.; Wang, Z.; Zhu, Y.; Gire, D. H.; Mizumori, S. J.

10.1101/2021.03.03.433785 — neuroscience — Posted on 2021-03-04

4313 Quantifying the subjective cost of self-control in humans

Raio, C. M.; Glimcher, P.

10.1101/2020.10.15.341354 — neuroscience — Posted on 2021-03-04

4314 Dual strategies in human confidence judgments

Bertana, A.; Chetverikov, A.; van Bergen, R. S.; Ling, S.; Jehee, J.

10.1101/2020.09.17.299743 — neuroscience — Posted on 2021-03-04

4315 SPOT: a web-tool enabling Swift Profiling Of Transcriptomes

Farr, E.; Sattler, J. M.; Frischknecht, F.

10.1101/2021.03.03.433767 — bioinformatics — Posted on 2021-03-04

4316 Sector search strategies for odor trail tracking

Reddy, G.; Shraiman, B. I.; Vergassola, M.

10.1101/2021.03.03.433838 — animal behavior and cognition — Posted on 2021-03-04

4317 Intra-species transcriptional profiling reveals key regulators of Candida albicans pathogenic traits

Wang, J. M.; Woodruff, A. L.; Dunn, M. J.; Fillinger, R.; Bennett, R. J.; Anderson, M. Z.

10.1101/2021.03.03.433840 — genomics — Posted on 2021-03-04

4318 In situ community dynamics influences the temperature- and light- dependent succession of seasonal phytoplankton

Tragin, M.; Lambert, S.; Lozano, J.-C.; Bouget, F.-Y.

10.1101/2021.03.03.433693 — ecology — Posted on 2021-03-04

4319 A computational approach to evaluate the combined effect of SARS-CoV-2 RBD mutations and ACE2 receptor genetic variants on infectivity: The COVID-19 host-pathogen nexus

Ashoor, D.; Ben Khalaf, N.; Marzouq, M.; Jarjanazi, H.; Chelif, S.; Fathallah, M. D.

10.1101/2020.10.23.352344 — molecular biology — Posted on 2021-03-04

4320 Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters

Dalvie, N. C.; Rodriguez-Aponte, S. A.; Hartwell, B. L.; Tostanoski, L. H.; Biedermann, A. M.; Crowell, L. E.; Kaur, K.; Kumru, O.; Carter, L.; Yu, J.; Chang, A.; McMahan, K.; Courant, T.; Lebas, C.; Lemnios, A. A.; Rodrigues, K. A.; Silva, M.; Johnston, R. S.; Naranjo, C. A.; Tracey, M. K.; Brady, J. R.; Whittaker, C. A.; Yun, D.; Kar, S.; Porto, M.; Lok, M.; Andersen, H.; Lewis, M. G.; Love, K. R.; Camp, D. L.; Silverman, J. M.; Kleanthous, H.; Joshi, S. B.; Volkin, D. B.; Dubois, P. M.; Collin, N.; King, N. P.; Barouch, D. H.; Irvine, D. J.; Love, J. C.

10.1101/2021.03.03.433558 — molecular biology — Posted on 2021-03-04

4321 Ribosome-profiling reveals restricted post transcriptional ex-pression of antiviral cytokines and transcription factors during SARS-CoV-2 infection

Alexander, M. R.; Brice, A. M.; Jansen Van Vuren, P.; Rootes, C.; Tribolet, L.; Cowled, C.; Bean, A. G. D.; Stewart, C. R.

10.1101/2021.03.03.433675 — microbiology — Posted on 2021-03-04

4322 High resolution profiling of MHC-II peptide presentation capacity, by Mammalian Epitope Display, reveals SARS-CoV-2 targets for CD4 T cells and mechanisms of immune-escape

Obermair, F. J.; Renoux, F.; Heer, S.; Lee, C.; Cereghetti, N.; Maestri, G.; Haldner, Y.; Wuigk, R.; Iosefson, O.; Patel, P.; Triebel, K.; Kopf, M.; Swain, J.; Kisielow, J.

10.1101/2021.03.02.433522 — immunology — Posted on 2021-03-04

4323 The CDK8 inhibitor DCA promotes a tolerogenic chemical immunophenotype in CD4+ T cells via a novel CDK8-GATA3-FOXP3 pathway

Arnett, A.; Moo, K. G.; Flynn, K. J.; Sundberg, T. B.; Johannessen, L.; Shamji, A. F.; Gray, N. S.; Decker, T.; Gersuk, V. H.; Levy, D. E.; Marie, I. J.; Rahman, Z. S.; Zheng, Y.; Linsley, P. S.; Xavier, R. J.; Khor, B.

10.1101/855429 — immunology — Posted on 2021-03-04

4324 V3 Interneurons Regulate Locomotor Vigor by Recruitment of Spinal Motor Neurons During Fictive Swimming in Larval Zebrafish

Wiggin, T. D.; Montgomery, J. E.; Brunick, A. J.; Peck, J. H.; Masino, M. A.

10.1101/2021.03.03.433646 — neuroscience — Posted on 2021-03-04

4325 In silico analyses of neuropeptide-like protein (NLP) profiles in parasitic nematodes

McKay, F. M.; McCoy, C. J.; Marks, N. J.; Maule, A. G.; Atkinson, L. E.; Mousley, A.

10.1101/2021.03.03.433794 — neuroscience — Posted on 2021-03-04

4326 Hippocampus and amygdala fear memory engrams re-emerge after contextual fear relapse

Zaki, Y.; Mau, W.; Cincotta, C.; Vieira, A.; Doucette, E.; Grella, S. L.; Merfeld, E.; Murawski, N. J.; Shpokayte, M.; Ramirez, S.

10.1101/2019.12.19.882795 — neuroscience — Posted on 2021-03-04

4327 PyADM1: a Python implementation of Anaerobic Digestion Model No. 1

Sadrimajd, P.; Mannion, P.; Howley, E.; Lens, P. N. L.

10.1101/2021.03.03.433746 — systems biology — Posted on 2021-03-04

4328 Large scale genomic rearrangements in selected Arabidopsis thaliana T-DNA lines are caused by T-DNA insertion mutagenesis

Pucker, B.; Kleinboelting, N.; Weisshaar, B.

10.1101/2021.03.03.433755 — plant biology — Posted on 2021-03-04

4329 Phenotyping heart failure using model-based analysis and physiology-informed machine learning

Jones, E.; Randall, E. B.; Hummel, S. L.; Cameron, D.; Beard, D. A.; Carlson, B. E.

10.1101/2021.03.03.433748 — physiology — Posted on 2021-03-04

4330 Sugar transporters enable a leaf beetle to accumulate plant defense compounds

Yang, Z.-L.; Nour-Eldin, H. H.; Haenniger, S.; Reichelt, M.; Crocoll, C.; Seitz, F.; Vogel, H.; Beran, F.

10.1101/2021.03.03.433712 — physiology — Posted on 2021-03-04

4331 Probiotic bacteria and bile acid profile are modulated by prebiotic diet and associate with facilitated diurnal clock/sleep realignment after chronic disruption of rhythms

Thompson, R. S.; Gaffney, M. K.; Hopkins, S.; Kelley, T.; Gonzalez, A.; Bowers, S. J.; Vitaterna, M. H.; Turek, F. W.; Foxx, C. L.; Lowry, C. A.; Vargas, F.; Dorrestein, P. C.; Wright, K. P.; Knight, R.; Fleshner, M.

10.1101/2021.03.03.433775 — physiology — Posted on 2021-03-04

4332 The methylation of SDC2 and TFPI2 defined three methylator phenotypes of colorectal cancer

Lei, R.; Zhao, Y.; Huang, K.; Wan, K.; Li, T.; Yang, H.; Lv, X.

10.1101/2021.03.03.433833 — cancer biology — Posted on 2021-03-04

4333 Cooperative regulation of coupled oncoprotein translation and stability in triple-negative breast cancer by EGFR and CDK12

Ang, H. X.; Sutiman, N.; Deng, X. L.; Bartelt, L. C.; Chen, Q.; Barrera, A.; Lin, J.; Sheng, J. Z.; McDowell, I. C.; Reddy, T. E.; Nicchitta, C. V.; Wood, K. C.

10.1101/2021.03.03.433762 — cancer biology — Posted on 2021-03-04

4334 Relative DOPA Deficiency in Lightly Pigmented Skin Contributes to UV-Independent Melanoma Susceptibility

Doepner, M.; Natale, C. A.; Ridky, T. W.

10.1101/2021.03.03.433757 — cancer biology — Posted on 2021-03-04

4335 Network Theory Reveals Principles of Spliceosome Structure and Dynamics

Kaur, H.; van der Feltz, C.; Sun, Y.; Hoskins, A. A.

10.1101/2021.03.03.433650 — biophysics — Posted on 2021-03-04

4336 An NCCN-IPI based immune-related gene prognostic model for diffuse large B-cell lymphoma

Mu, S.; Shi, D.; Ai, L.; Fan, F.; Peng, F.; Sun, C.; Hu, Y.

10.1101/2021.03.03.433839 — bioinformatics — Posted on 2021-03-04

4337 A causal role for the right frontal eye fields in value comparison

Krajbich, I.; Mitsumasu, A.; Polania, R.; Ruff, C.; Fehr, E.

10.1101/2021.03.03.433716 — bioinformatics — Posted on 2021-03-04

4338 Spt4 Facilitates the Movement of RNA Polymerase II through the +2 Nucleosomal Barrier

Uzun, U.; Brown, T.; Fischl, H. J.; Angel, A.; Mellor, J.

10.1101/2021.03.03.433772 — genomics — Posted on 2021-03-04

4339 Evaluating the role of reference-genome phylogenetic distance on evolutionary inference

Prasad, A.; Lorenzen, E. D.; Westbury, M. V.

10.1101/2021.03.03.433733 — evolutionary biology — Posted on 2021-03-04

4340 Joint identification of sex and sex-linked scaffolds in non-model organisms using low depth sequencing data

Nursyifa, C.; Bruniche-Olsen, A.; Garcia-Erill, G.; Heller, R.; Albrechtsen, A.

10.1101/2021.03.03.433779 — evolutionary biology — Posted on 2021-03-04

4341 Manipulating vector transmission reveals local processes in bacterial communities of bats

McKee, C. D.; Webb, C. T.; Kosoy, M. Y.; Bai, Y.; Osikowicz, L. M.; Suu-Ire, R.; Ntiamoa-Baidu, Y.; Cunningham, A. A.; Wood, J. L.; Hayman, D. T.

10.1101/2021.03.03.433743 — ecology — Posted on 2021-03-04

4342 Landscape connectivity alters the evolution of density-dependent dispersal during pushed range expansions

Dahirel, M.; Bertin, A.; Calcagno, V.; Duraj, C.; Fellous, S.; Groussier, G.; Lombaert, E.; Mailleret, L.; Marchand, A.; Vercken, E.

10.1101/2021.03.03.433752 — ecology — Posted on 2021-03-04

4343 Quantitative estimates of deciduousness in woody species from a seasonally dry tropical forest are related to leaf functional traits and the timing of leaf flush

Chakrabarty, S.; Sharma, S.; Ganguly, S.; Jezeera, A.; Mohanbabu, N.; Barua, D.

10.1101/2021.03.03.433407 — ecology — Posted on 2021-03-04

4344 Comparison of Chronic Wasting Disease Detection Methods and Procedures: implications for free-ranging white-tailed deer (Odocoileus virginianus) surveillance and management

Schwabenlander, M. D.; Rowden, G. R.; Li, M.; LaSharr, K.; Hildebrand, E. C.; Stone, S.; Seelig, D. M.; Jennelle, C. S.; Cornicelli, L.; Wolf, T. M.; Carstensen, M.; Larsen, P. A.

10.1101/2021.03.03.433751 — ecology — Posted on 2021-03-04

4345 The Post-2020 Global Biodiversity Framework must safeguard the Tree of Life

Gumbs, R.; Chaudhary, A.; Daru, B. H.; Faith, D. P.; Forest, F.; Gray, C. L.; Kowalska, A.; Lee, W.-S.; Pellens, R.; Pollock, L. J.; Rosindell, J.; Scherson, R. A.; Owen, N. R.

10.1101/2021.03.03.433783 — ecology — Posted on 2021-03-04

4346 Characterization of the neurogenic niche in the aging dentate gyrus using iterative immunofluorescence imaging

Jessberger, S.; Cole, J.

10.1101/2021.03.03.433747 — neuroscience — Posted on 2021-03-04

4347 Insights into the susceptibility of rice to a floral disease

10.1101/2021.03.03.433744 — plant biology — Posted on 2021-03-04

4348 Organelle genome assembly uncovers the dynamic genome reorganization and cytoplasmic male sterility associated genes in tomato.

Kuwabara, K.; Harada, I.; Matsuzawa, Y.; Ariizumi, T.; Shirasawa, K.

10.1101/2021.03.03.433741 — plant biology — Posted on 2021-03-04

4349 Proteasome maturation factor UMP1 confers broad-spectrum disease resistance by modulating H2O2 accumulation in rice

Hu, X.-H.; Fan, J.; Wu, J.-L.; Shen, S.; He, J.-X.; Liu, J.; Wang, H.; Zhu, Y.; Li, G.-B.; Zhao, J.-H.; Xu, J.; Li, D.-Q.; Pu, M.; Zhao, Z.-X.; Zhou, S.-X.; Zhang, J.-W.; Huang, Y.-Y.; Li, Y.; Lu, Y.-L.; Huang, F.; Wang, W.-M.

10.1101/2021.03.03.433750 — plant biology — Posted on 2021-03-04

4350 Complementary Phenotyping of Maize Root Architecture by Root Pulling Force and X-Ray Computed Tomography

Shao, M.-R.; Jiang, N.; Li, M.; Howard, A.; Lehner, K.; Mullen, J. L.; Gunn, S. L.; McKay, J.; Topp, C. N.

10.1101/2021.03.03.433776 — plant biology — Posted on 2021-03-04

4351 The quasi-universality of nestedness in the structure of quantitative plant-parasite interactions

Moury, B.; Audergon, J.-M.; Baudracco-Arnas, S.; BEN KRIMA, S.; Bertrand, F.; Boissot, N.; Buisson, M.; Caffier, V.; Cantet, M.; Chaneac, S.; Constant, C.; Delmotte, F.; Dogimont, C.; Doumayrou, J.; Fabre, F.; Fournet, S.; Grimault, V.; Jaunet, T.; Justafre, I.; Lefebvre, V.; Losdat, D.; MARCEL, T. C.; Montarry, J.; Morris, C. E.; Omrani, M.; Paineau, M.; Perrot, S.; Pilet-Nayel, M.-L.; Ruellan, Y.

10.1101/2021.03.03.433745 — pathology — Posted on 2021-03-04

4352 Targeting LDHC dysregulates the cell cycle and improves sensitivity to cisplatin and olaparib

Naik, A.; Decock, J.

10.1101/2021.03.03.433525 — cancer biology — Posted on 2021-03-04

Liu, Z.; Barahona, M.

10.1101/2021.03.03.433709 — bioinformatics — Posted on 2021-03-04

4354 Linguistic Analysis of the bioRxiv Preprint Landscape

Nicholson, D. N.; Rubinetti, V.; Hu, D.; Think, M.; Hunter, L. E.; Greene, C. S.

10.1101/2021.03.04.433874 — bioinformatics — Posted on 2021-03-04

4355 Physiologic flow-conditioning limits vascular dysfunction in engineered human capillaries

Haase, K.; Piatti, F.; Marcano, M.; Shin, Y.; Visone, R.; Redaelli, A.; Rasponi, M.; Kamm, R. D.

10.1101/2021.03.03.433247 — bioengineering — Posted on 2021-03-04

4356 Concept design of a bionic grasp to capture the hand motion

Islam, M.; Li, X.; Chizari, M.

10.1101/2021.03.03.433703 — bioengineering — Posted on 2021-03-04

4357 Closer appendage spacing augments metachronal swimming speed by promoting tip vortex interactions

Ford, M. P.; Santhanakrishnan, A.

10.1101/2021.03.03.433771 — bioengineering — Posted on 2021-03-04

4358 Towards a standardization of non-symbolic numerical experiments: GeNEsIS, a flexible and user-friendly tool to generate controlled stimuli

Zanon, M.; Potrich, D.; Bortot, M.; Vallortigara, G.

10.1101/2021.03.03.433737 — animal behavior and cognition — Posted on 2021-03-04

4359 Integrating structured and unstructured citizen science data to improve wildlife population monitoring

Boersch-Supan, P. H.; Robinson, R. A.

10.1101/2021.03.03.431294 — ecology — Posted on 2021-03-04

4360 Dopamine and serotonin interplay for valence-based spatial learning

Wert Carvajal, C.; Reneaux, M.; Tchumatchenko, T.; Clopath, C.

10.1101/2021.03.04.433867 — neuroscience — Posted on 2021-03-04

4361 Synaptic plasticity in distal dendrites can optimize probabilistic top-down predictions in pyramidal cells

Rao, A.; Legenstein, R.; Subramoney, A.; Maass, W.

10.1101/2021.03.04.433822 — neuroscience — Posted on 2021-03-04

4362 Kinetic structure of recycling vesicle pool at the Calyx of Held synapse under in vivo-like activities

Sun, J.; Liu, Z.; Zhu, Y.; Hu, Y.

10.1101/2021.03.03.433702 — neuroscience — Posted on 2021-03-04

4363 CaSR modulates sodium channel-mediated Ca 2+ -dependent excitability

Martiszus, B. J.; Tsintsadze, T.; Smith, S. M.; Chang, W.

10.1101/2021.03.03.433701 — neuroscience — Posted on 2021-03-04

4364 Head-Direction Coding in the Hippocampal Formation of Birds

Ben-Yishay, E.; Krivoruchko, K.; Ron, S.; Ulanovsky, N.; Derdikman, D.; Gutfreund, Y.

10.1101/2020.08.31.274928 — neuroscience — Posted on 2021-03-04

4365 Gut microbial ecology of Xenopus tadpoles across life stages

Scalvenzi, T.; Clavereau, I.; Bourge, M.; Pollet, N.

10.1101/2020.05.25.110734 — genomics — Posted on 2021-03-04

4366 Autism-associated CHD8 keeps proliferation of human neural progenitors in check by lengthening the G1 phase of the cell cycle

Coakley-Youngs, E.; Shorter, S.; Ranatunga, M.; Richardson, S. C.; Getti, G. T.; Fivaz, M.

10.1101/2021.03.03.433829 — neuroscience — Posted on 2021-03-04

4367 Collective behavior emerges from genetically controlled simple behavioral motifs in zebrafish

Aspiras, A. C.; Harpaz, R.; Chambule, S.; Tseng, S.; Engert, F.; Fishman, M. C.; Bahl, A.

10.1101/2021.03.03.433803 — animal behavior and cognition — Posted on 2021-03-04

4368 Matrix-Assisted Laser Desorption-Ionization Time-of-Flight mass spectrometry using a custom-made database, biomarker assignment, or mathematical classifiers does not differentiate Shigella spp. and Escherichia coli

van den Beld, M. J. C.; Rossen, J. W. A.; Evers, A.; Kooistra-Smid, M. A. M. D.; Reubsaet, F. A. G.

10.1101/714295 — microbiology — Posted on 2021-03-04

4369 The landscape of accessible chromatin in quiescent and post-myocardial infarction cardiac fibroblasts

Li, C.; Sun, J.; Liu, Q.; Dodlapati, S.; Ming, H.; Wang, L.; Li, Y.; Li, R.; Jiang, Z.; Francis, J.; Fu, X.

10.1101/2021.03.03.433814 — genomics — Posted on 2021-03-04

4370 Neuronal ROS-Induced Glial Lipid Droplet Formation is Altered by Loss of Alzheimers Disease-associated Genes

Moulton, M. J.; Barish, S.; Ralhan, I.; Chang, J.; Goodman, L. D.; Harland, J.; Marcogliese, P. C.; Johansson, J.; Ioannou, M.; Bellen, H. J.

10.1101/2021.03.03.433580 — genetics — Posted on 2021-03-04

4371 The wheat 55K SNP-based exploration of loci for spikelet number per spike from a tetraploid wheat (Triticum turgidum L.) recombinant inbred line population derived from a Chinese landrace Ailanmai and a wild emmer accession

Mo, Z.; Zhu, J.; Wei, J.; Zhou, J.; Xu, Q.; Tang, H.; Mu, Y.; Jiang, Q.; Liu, Y.; Chen, G.; Wang, J.; Qi, P.; Pu, Z.; Chen, G.; Wei, Y.; Zheng, Y.; Lan, X.; Ma, J.

10.1101/2020.10.21.348227 — genetics — Posted on 2021-03-04

4372 Evolutionary forecasting of phenotypic and genetic outcomes of experimental evolution in Pseudomonas protegens

Pentz, J. T.; Lind, P. A.

10.1101/342261 — evolutionary biology — Posted on 2021-03-04

4373 Nucleotide substitutions during speciation may explain substitution rate variation

Janzen, T.; Bokma, F.; Etienne, R. S.

10.1101/2020.08.19.256891 — evolutionary biology — Posted on 2021-03-04

4374 Left/right asymmetry disruptions and mirror-image reversals to behavior andbrain anatomy in Ciona

Kourakis, M. J.; Bostwick, M.; Zabriskie, A.; Smith, W.

10.1101/2021.03.03.433807 — developmental biology — Posted on 2021-03-04

4375 No behavioral evidence for rhythmic facilitation of perceptual discrimination

Lin, W. M.; Oetringer, D.; Bakker-Marshall, I.; Emmerzaal, J.; Wilsch, A.; ElShafei, H. A.; El Rassi, E.; Haegens, S.

10.1101/2020.12.10.418947 — neuroscience — Posted on 2021-03-04

4376 Protein appetite drives macronutrient-related differences in ventral tegmental area neural activity

Chiacchierini, G.; Naneix, F.; Peters, K. Z.; Apergis-Schoute, J.; Snoeren, E. M.; McCutcheon, J.

10.1101/542340 — neuroscience — Posted on 2021-03-04

4377 Oxidative stress induced by tBHP in human normal colon cells by label free Raman spectroscopy and imaging.The protective role of natural antioxidants in the form of β-carotene

Pluska, B. B.; Beton, K.

10.1101/2021.02.16.431391 — cancer biology — Posted on 2021-03-04

4378 Resolving complex structures at oncovirus integration loci with conjugate graph

Jia, W.; Xu, C.; Li, S. C.

10.1101/2020.05.17.100578 — bioinformatics — Posted on 2021-03-04

4379 Collective motion as a distinct behavioral state of the individual

Knebel, D.; Sha-ked, C.; Agmon, N.; Ariel, G.; Ayali, A.

10.1101/2020.06.15.152454 — ecology — Posted on 2021-03-04

4380 Effect of high-frequency low-intensity pulsed electric field on protecting SH-SY5Y cells against hydrogen peroxide and β-amyloid-induced cell injury via ERK pathway

Chen, W.-T.; Lin, G.-B.; Kuo, Y.-Y.; Hsieh, C.-H.; Lu, C.-H.; Sun, Y.-K.; Chao, C.-Y.

10.1101/2019.12.30.891499 — neuroscience — Posted on 2021-03-04

4381 Intrinsic cardiac adrenergic cells contribute to septic cardiomyopathy

Yang, D.; Dai, X.; Xing, Y.; Tang, X.; Yang, G.; Wang, P.; Harrison, A. G.; Li, H.; Lv, X.; Yu, X.; Wang, H.

10.1101/2021.03.02.433552 — immunology — Posted on 2021-03-04

4382 Avalanches During Epithelial Tissue Growth; Uniform Growth and a Drosophila Eye Disc Model

Courcoubetis, G.; Xu, C.; Nuzhdin, S. V.; Haas, S.

10.1101/2021.03.01.433318 — biophysics — Posted on 2021-03-04

4383 Multiscale and integrative single-cell Hi-C analysis with Higashi

Zhang, R.; Zhou, T.; Ma, J.

10.1101/2020.12.13.422537 — bioinformatics — Posted on 2021-03-04

4384 Scorepochs: a computer-aided scoring tool for resting-state M/EEG epochs

Fraschini, M.; La Cava, S. M.; Rodriguez, G.; Demuru, M.

10.1101/2020.05.26.116434 — bioengineering — Posted on 2021-03-04

4385 Effect of wall type, delayed mortality and mosquito age on the residual efficacy of a clothianidin-based indoor residual spray formulation (SumiShieldTM 50WG) in southern Mozambique

Marti-Soler, H.; Maquina, M.; Opiyo, M.; Alafo, C.; Sherrard-Smith, E.; Malheia, A.; Cuamba, N.; Sacoor, C.; Rabinovich, R.; Aide, P.; Saute, F.; Paaijmans, K. P.

10.1101/2021.03.03.433723 — ecology — Posted on 2021-03-03

4386 Analysis of coding variants in the human FTO gene from the ExAC (gnomAD) Database

Souza Junior, M. L. F.; Sousa, J. V.; Guerreiro, J. F.

10.1101/2021.03.03.433730 — molecular biology — Posted on 2021-03-03

4387 Identification of gene products involved in plant colonization by Pantoea sp. YR343 using a diguanylate cyclase expressed in the presence of plants

Bible, A. N.; Chang, M.; Morrell-Falvey, J. L.

10.1101/2021.03.03.433726 — microbiology — Posted on 2021-03-03

4388 Modulation of early level EEG signatures by distributed facial emotion cues

Costa, D.; Dias, C.; Estiveira, J.; Castelhano, J.; Figueiredo, V.; Pereira, A.; Sousa, T.; Castelo-Branco, M.

10.1101/2021.03.03.433729 — neuroscience — Posted on 2021-03-03

4389 Dopaminergic signaling supports auditory social learning

Paraouty, N.; Rizzuto, C. R.; Sanes, D. H.

10.1101/2021.03.03.433719 — neuroscience — Posted on 2021-03-03

4390 Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP target transcripts

Dalal, J.; Winden, K. D.; Salussolia, C. L.; Sundberg, M.; Singh, A.; Zhou, P.; T Pu, W.; Miller, M. T.; Sahin, M.

10.1101/2021.03.03.433717 — neuroscience — Posted on 2021-03-03

4391 Apparent digestibility of captive colobines in relation to stomach types with special reference to fibre digestion

Hoshino, S.; Seino, S.; Funahashi, T.; Hoshino, T.; Clauss, M.; Matsuda, I.; Yayota, M.

10.1101/2021.03.02.433677 — zoology — Posted on 2021-03-03

4392 Bayesian calibration of a stochastic, multiscale agent-based model for predicting in vitro tumor growth

Lima, E. A. B. F.; Faghihi, D.; Philley, R.; Yang, J.; Virostko, J.; Phillips, C. M.; Yankeelov, T.

10.1101/2021.03.03.433731 — cancer biology — Posted on 2021-03-03

4393 PPIDomainMiner : Inferring domain-domain interactions from multiple sources of protein-protein interactions

Alborzi, S. Z.; Ahmed-Nacer, A.; Najjar, H.; Ritchie, D. W.; Devignes, M.-D.

10.1101/2021.03.03.433732 — bioinformatics — Posted on 2021-03-03

4394 Development and validation of FootNet; a new kinematic algorithm to improve foot-strike and toe-off detection in treadmill running

Rivadulla, A.; Chen, X.; Weir, G.; Cazzola, D.; Trewartha, G.; Hamill, J.; Preatoni, E.

10.1101/2021.03.03.433728 — bioinformatics — Posted on 2021-03-03

4395 Autism spectrum disorder: understanding the impact of SNPs on biological pathways in the fetal and adult cortex.

Golovina, E.; Fadason, T.; Lints, T.; Walker, C.; Vickers, M. H.; O'Sullivan, J. M.

10.1101/2021.03.03.433667 — genomics — Posted on 2021-03-03

4396 Schizosaccharomyces pombe KAT5 contributes to resection and repair of a DNA double strand break

Li, T.; Petreaca, R. C.; Forsburg, S. L.

10.1101/2020.06.03.132316 — genetics — Posted on 2021-03-03

4397 Study on Changes in Tourism Land and Influence Factors in Mountain Areas?A Case Study of Luanchuan County, China

Xie, Y.; Zhu, Q.

10.1101/2021.03.03.433724 — ecology — Posted on 2021-03-03

4398 A Cultured Sensorimotor Organoid Model Forms Human Neuromuscular Junctions

Pereira, J. D.; DuBreuil, D. M.; Devlin, A.-C.; Held, A.; Sapir, Y.; Berezovski, E.; Hawrot, J.; Dorfman, K.; Chander, V.; Wainger, B. J.

10.1101/2021.03.03.433128 — neuroscience — Posted on 2021-03-03

4399 Laminar-specific functional connectivity mapping with multi-slice line-scanning fMRI

Choi, S.; Zeng, H.; Chen, Y.; Sobczak, F.; Qian, C.; Yu, X.

10.1101/2021.03.03.433376 — neuroscience — Posted on 2021-03-03

4400 The connectome spectrum as a canonical basis for a sparse representation of fast brain activity

Rue Queralt, J.; Glomb, K.; Pascucci, D.; Tourbier, S.; Carboni, M.; Vulliemoz, S.; Plomp, G.; Hagmann, P.

10.1101/2021.03.03.433561 — neuroscience — Posted on 2021-03-03

4401 Loneliness and the social brain: how perceived social isolation impairs human interactions

Lieberz, J.; Shamay-Tsoory, S. G.; Saporta, N.; Esser, T.; Kuskova, E.; Stoffel-Wagner, B.; Hurlemann, R.; Scheele, D.

10.1101/2021.03.03.433569 — neuroscience — Posted on 2021-03-03

4402 Genetic demultiplexing of pooled single-cell RNA-sequencing samples in cancer facilitates effective experimental design

Weber, L. M.; Hippen, A. A.; Hickey, P. F.; Berrett, K. C.; Gertz, J.; Doherty, J. A.; Greene, C. S.; Hicks, S. C.

10.1101/2020.11.06.371963 — bioinformatics — Posted on 2021-03-03

4403 Identification of in vivo CFTR conformations during biogenesis and upon misfolding by covalent protein painting (CPP)

Pankow, S.; Bamberger, C.; Martinez-Bartolome, S.; Park, S. K.; Yates, J. R.

10.1101/2021.03.02.433670 — molecular biology — Posted on 2021-03-03

4404 Co-occupancy analysis reveals novel transcriptional synergies for axon growth

Venkatesh, I.; Mehra, V.; Wang, Z.; Simpson, M. T.; Eastwood, E.; Chakraborty, A.; Beine, Z.; Gross, D.; Cabahug, M.; Olson, G.; Blackmore, M. G.

10.1101/2020.06.12.146159 — neuroscience — Posted on 2021-03-03

4405 Lymphocyte-specific Protein Tyrosine Kinase Regulates Homologous Recombination (HR) DNA Repair and Targeting Enhances PARPi Utility in HR Proficient Ovarian Cancer

Dey, G.; Bharti, R.; Braley, C.; Alluri, R.; Esakov, E.; Crean-Tate, K.; McCrae, K.; Joehlin-Price, A.; Rose, P. G.; Lathia, J.; Gong, Z.; Reizes, O.

10.1101/2021.03.03.433791 — cancer biology — Posted on 2021-03-03

4406 The role of mechanical interactions in EMT

Murphy, R. J.; Buenzli, P. R.; Tambyah, T. A.; Thompson, E. W.; Hugo, H. J.; Baker, R. E.; Simpson, M. J.

10.1101/2020.12.09.418434 — biophysics — Posted on 2021-03-03

4407 CoSTA: Unsupervised Convolutional Neural Network Learning for Spatial Transcriptomics Analysis

Xu, Y.; McCord, R. P.

10.1101/2021.01.12.426400 — bioinformatics — Posted on 2021-03-03

4408 A ChIP-exo screen of 887 PCRP transcription factor antibodies in human cells

Lai, W. K.; Mariani, L.; Rothschild, G.; Smith, E. R.; Venters, B. J.; Blanda, T. R.; Kuntala, P. K.; Bocklund, K.; Mairose, J.; Dweikat, S. N.; Mistretta, K.; Rossi, M. J.; James, D.; Anderson, J. T.; Phanor, S. K.; Zhang, W.; Zhao, Z.; Shaw, A. P.; Novitzky, K.; McAnarney, E.; Keogh, M.-C.; Shilatifard, A.; Basu, U.; Bulyk, M.; Pugh, B. F.

10.1101/2020.06.08.140046 — biochemistry — Posted on 2021-03-03

4409 The first steps toward a global pandemic: Reconstructing the demographic history of parasite host switches in its native range

Techer, M. A.; Roberts, J. M. K.; Cartwright, R. A.; Mikheyev, A. S.

10.1101/2020.07.30.228320 — genomics — Posted on 2021-03-03

4410 X chromosome-dependent disruption of placental regulatory networks in hybrid dwarf hamsters

Brekke, T. D.; Moore, E. C.; Campbell-Staton, S. C.; Callahan, C. M.; Cheviron, Z. A.; Good, J. M.

10.1101/2020.09.15.298893 — evolutionary biology — Posted on 2021-03-03

4411 Novel newt regeneration genes regulate Wingless signaling to restore patterning in Drosophila eye

Mehta, A. S.; Deshpande, P.; Chimata, A. V.; Tsonis, P. A.; Singh, A.

10.1101/2021.02.28.433269 — developmental biology — Posted on 2021-03-03

4412 Brain deletion of Serf2 shifts amyloid conformation in a mouse model

Stroo, E.; Janssen, L.; Sin, O.; Hogewerf, W.; Koster, M. H.; Harkema, L.; Youssef, S. A.; beschorner, N.; Wolters, A. H. G.; Bakker, B.; Thathiah, A.; Foijer, F.; van de Sluis, B.; van Deursen, J.; Jucker, M.; de Bruin, A.; Nollen, E.

10.1101/2021.01.05.423442 — molecular biology — Posted on 2021-03-03

4413 Preexisting memory CD4 T cells in nÏave individuals confer robust immunity upon hepatitis B vaccination

Elias, G.; Meysman, P.; Bartholomeus, E.; De Neuter, N.; Keersmaekers, N.; Suls, A.; Jansens, H.; Souquette, A.; De Reu, H.; Smits, E.; Lion, E.; Thomas, P. G.; Mortier, G.; Van Damme, P.; Beutels, P.; Laukens, K.; Van Tendeloo, V.; Ogunjimi, B.

10.1101/2020.08.22.262568 — immunology — Posted on 2021-03-03

4414 Ex vivo delivery of regulatory T cells for control of alloimmune priming in the donor lung

Miyamoto, E.; Takahagi, A.; Ohsumi, A.; Martinu, T.; Hwang, D.; Boonstra, K.; Joe, B.; Juan Umana, M.; Bei, K.; Vosoughi, D.; Liu, M.; Cypel, M.; Keshavjee, S.; Juvet, S. C.

10.1101/2021.02.07.430098 — immunology — Posted on 2021-03-03

4415 A dynamic gradient architecture generates brain activity states

Brown, J. A.; Lee, A. J.; Pasquini, L.; Seeley, W. W.

10.1101/2020.08.12.248112 — neuroscience — Posted on 2021-03-03

4416 Emerging experience-dependent dynamics in primary somatosensory cortex reflect behavioral adaptation

Waiblinger, C.; Borden, P. Y.; Stanley, G. B.

10.1101/2021.01.29.428886 — neuroscience — Posted on 2021-03-03

4417 Probing machine-learning classifiers using noise, bubbles, and reverse correlation

Thoret, E.; Andrillon, T.; Leger, D.; Pressnitzer, D.

10.1101/2020.06.22.165688 — neuroscience — Posted on 2021-03-03

4418 Oscillatory tracking of pseudo-rhythmic speech is constrained by linguistic predictions

ten Oever, S.; Martin, A. E.

10.1101/2020.12.07.414425 — neuroscience — Posted on 2021-03-03

4419 Social Reactivation of Fear Engrams Enhances Recall and Reinstatement

Finkelstein, A. B.; Leblanc, H.; Cole, R.; Gallerani, T.; Vieira, A.; Zaki, Y.; Ramirez, S.

10.1101/2021.01.07.425728 — neuroscience — Posted on 2021-03-03

4420 Emergence of function from single RNA sequences by Darwinian evolution

Holliger, P.; Wachowius, F.; Porebski, B. T.; Johnson, C. M.

10.1101/2021.03.03.433769 — synthetic biology — Posted on 2021-03-03

4421 A fungal powdery mildew pathogen induces extensive local and marginal systemic changes in the Arabidopsis thaliana microbiota

Duran, P.; Reinstaedler, A.; Rajakrut, A. L.; Hashimoto, M.; Garrido-Oter, R.; Schulze-Lefert, P.; Panstruga, R.

10.1101/2021.02.26.432829 — plant biology — Posted on 2021-03-03

4422 ZIP9 is a Druggable Determinant of Sex Differences in Melanoma

Aguirre-Portoles, C.; Payne, R.; Trautz, A.; Foskett, J. K.; Natale, C. A.; Seykora, J. T.; Ridky, T. W.

10.1101/2020.03.12.989160 — cancer biology — Posted on 2021-03-03

4423 Cell Communication Network factor 4 promotes tumor-induced immunosuppression in melanoma

Fernandez, A.; Deng, W.; McLaughlin, S. L.; Pirkey, A. C.; Rellick, S.; Klinke, D. J.

10.1101/2021.02.23.432584 — cancer biology — Posted on 2021-03-03

4424 Direct simulation of a stochastically driven multi-step birth-death process

Gorin, G.; Pachter, L.

10.1101/2021.01.20.427480 — biophysics — Posted on 2021-03-03

4425 Comparative analysis of codon usage patterns in SARS-CoV-2, its mutants and other respiratory viruses

Tyagi, N.; Sardar, R.; Gupta, D.

10.1101/2021.03.03.433699 — bioinformatics — Posted on 2021-03-03

4426 Benchmarking of lightweight-mapping based single-cell RNA-seq pre-processing

Booeshaghi, A. S.; Pachter, L.

10.1101/2021.01.25.428188 — bioinformatics — Posted on 2021-03-03

4427 AncestralClust: Clustering of Divergent Nucleotide Sequences by Ancestral Sequence Reconstruction using Phylogenetic Trees

Pipes, L.; Nielsen, R.

10.1101/2021.01.08.426008 — bioinformatics — Posted on 2021-03-03

4428 Characterising ontogeny of numerosity discrimination in zebrafish reveals multiple, numerical and non- numerical mechanisms.

Sheardown, E.; Torres-Perez, J. V.; Anagianni, S.; Fraser, S.; Vallortigara, G.; Butterworth, B.; Miletto-Petrazzini, M. E.; Brennan, C. H.

10.1101/2021.02.25.432846 — animal behavior and cognition — Posted on 2021-03-03

4429 Non-Parametric Analysis of Inter-Individual Relations Using an Attention-Based Neural Network

Morita, T.; Toyoda, A.; Aisu, S.; Kaneko, A.; Suda-Hashimoto, N.; Adachi, I.; Matsuda, I.; Koda, H.

10.1101/2020.03.25.994764 — animal behavior and cognition — Posted on 2021-03-03

4430 The genome sequence of the cereal pest Sitophilus oryzae: an unprecedented transposable element content

Parisot, N.; Vargas-Chavez, C.; Goubert, C.; Baa-Puyoulet, P.; Balmand, S.; Beranger, L.; Blanc, C.; Bonnamour, A.; Boulesteix, M.; Burlet, N.; Calevro, F.; Callaerts, P.; Chancy, T.; Charles, H.; Colella, S.; Da Silva Barbosa, A.; Dell'Aglio, E.; Di Genova, A.; Febvay, G.; Gabaldon, T.; Galvao Ferrarini, M.; Gerber, A.; Gillet, B.; Hubley, R.; Hughes, S.; Jacquin-Joly, E.; Maire, J.; Marcet-Houben, M.; Masson, F.; Meslin, C.; Montagne, N.; Moya, A.; Ribeiro de Vasconcelos, A. T.; Richard, G.; Rosen, J.; Sagot, M.-F.; Smit, A. F.; Storer, J.; Vincent-Monegat, C.; Vallier, A.; Vigneron, A.; Zai

10.1101/2021.03.03.408021 — genomics — Posted on 2021-03-03

4431 Constructing Local Cell Sepcific Networks from Single Cell Data

Wang, X.; Choi, D.; Roeder, K.

10.1101/2021.02.13.431104 — genomics — Posted on 2021-03-03

4432 A Generalized Robust Allele-based Genetic Association Test

Zhang, L.; Sun, L.

10.1101/2020.03.12.989004 — genetics — Posted on 2021-03-03

4433 Paralogous gene modules derived from ancient hybridization drive vesicle traffic evolution in yeast

Purkanti, R.; Thattai, M.

10.1101/2021.03.03.433305 — evolutionary biology — Posted on 2021-03-03

4434 Recapitulate Human Cardio-pulmonary Co-development Using Simultaneous Multilineage Differentiation of Pluripotent Stem Cells

Ng, W. H.; Johnston, E. K.; Tan, J. J.; Bliley, J. M.; Feinberg, A. W.; Stolz, D. B.; Sun, M.; Hawkins, F.; Kotton, D. N.; Ren, X.

10.1101/2021.03.03.433714 — developmental biology — Posted on 2021-03-03

4435 RNA polymerase backtracking results in the accumulation of fission yeast condensin at active genes

Rivosecchi, J.; Jost, D.; Vachez, L.; Gautier, F.; Bernard, P.; Vanoosthuyse, V.

10.1101/2020.11.13.381434 — cell biology — Posted on 2021-03-03

4436 SWI/SNF senses carbon starvation with a pH-sensitive low complexity sequence

Gutierrez, J. I.; Brittingham, G. P.; Karadeniz, Y. B.; Tran, K. D.; Dutta, A.; Holehouse, A. S.; Peterson, C. L.; Holt, L. J.

10.1101/2021.03.03.433592 — molecular biology — Posted on 2021-03-03

4437 On-site genomic epidemiological analysis of antimicrobial-resistant bacteria in Cambodia with portable laboratory equipment

Hirabayashi, A.; Yanagisawa, H.; Takahashi, H.; Yahara, K.; Boeing, P.; Wolfenden, B.; Nov, V.; Lorn, V.; Veng, M.; Ann, V.; Darapheak, C.; Shibayama, K.; Suzuki, M.

10.1101/2021.03.03.433720 — microbiology — Posted on 2021-03-03

4438 Patterns of gene content and co-occurrence constrain the evolutionary path toward animal association in CPR bacteria

Jaffe, A. L.; He, C.; Keren, R.; Valentin-Alvarado, L. E.; Munk, P. L.; Bouma-Gregson, K.; Amano, Y.; West, P. T.; Banfield, J. F.

10.1101/2021.03.03.433784 — microbiology — Posted on 2021-03-03

4439 ARG1 could be expressed by human, but not represent for repair

Chu, C.; Hu, C.; Rung, S.; Wang, Y.; Qu, Y.; Man, Y.

10.1101/2020.07.02.183624 — immunology — Posted on 2021-03-03

4440 NuMorph: tools for cellular phenotyping in tissue cleared whole brain images

Krupa, O.; Fragola, G.; Hadden-Ford, E.; Mory, J. T.; Liu, T.; Humphrey, Z.; Krishnamurthy, A.; Snider, W.; Zylka, M. J.; Wu, G.; Xing, L.; Stein, J. L.

10.1101/2020.09.11.293399 — neuroscience — Posted on 2021-03-03

4441 Neurocomputational underpinnings of expected surprise

Lecaignard, F.; Bertrand, O.; Caclin, A.; Mattout, J.

10.1101/501221 — neuroscience — Posted on 2021-03-03

4442 Hemodynamic responses link individual differences in informational masking to the vicinity of superior temporal gyrus

Zhang, M.; Alamatsaz, N.; Ihlefeld, A.

10.1101/2020.08.21.261222 — neuroscience — Posted on 2021-03-03

4443 Expectation-Based Gist Facilitation: Rapid Scene Understanding and the Role of Top-Down Information

McLean, D.; Renoult, L.; Malcolm, G. L.

10.1101/2021.02.04.429791 — neuroscience — Posted on 2021-03-03

4444 On the generalizability of diffusion MRI signal representations across acquisition parameters, sequences and tissue types: chronicles of the MEMENTO challenge.

De Luca, A.; Ianus, A.; Leemans, A.; Palombo, M.; Shemesh, N.; Zhang, H.; Alexander, D. C.; Nilsson, M.; Froeling, M.; Biessels, G.-J.; Zucchelli, M.; Frigo, M.; Albay, E.; Sedlar, S.; Alimi, A.; Deslauriers-Gauthier, S.; Deriche, R.; Fick, R.; Afzali, M.; Pieciak, T.; Bogusz, F.; Aja-Fernandez, S.; Ozarslan, E.; Jones, D. K.; Chen, H.; Jin, M.; Zhang, Z.; Wang, F.; Nath, V.; Parvathaneni, P.; Morez, J.; Sijbers, J.; Jeurissen, B.; Fadnavis, S.; Endres, S.; Rokem, A.; Garyfallidis, E.; Sanchez, I.; Prchkovska, V.; Rodrigues, P.; Landman, B. A.; Schilling, K. G.

10.1101/2021.03.02.433228 — neuroscience — Posted on 2021-03-03

4445 Synaptic learning rules for sequence learning

Reifenstein, E. T.; Richard, K.

10.1101/2020.04.13.039826 — neuroscience — Posted on 2021-03-03

4446 Evidence of post-domestication hybridization and adaptive introgression in Western European grapevine varieties

Freitas, S.; Gazda, M. A.; Rebelo, M.; Munoz-Pajares, A. J.; Vila-Vicosa, C. M.; Munoz-Merida, A.; Goncalves, L. M.; Azevedo-Silva, D.; Afonso, S.; Castro, I.; Castro, P. H.; Sottomayor, M.; Beja-Pereira, A.; Tereso, J.; Ferrand, N.; Goncalves, E.; Martins, A.; Carneiro, M.; Azevedo, H.

10.1101/2021.03.03.432021 — plant biology — Posted on 2021-03-03

4447 Medium-throughput zebrafish optogenetic platform identifies deficits in subsequent neural activity following brief early exposure to cannabidiol and Δ-9-tetrahydrocannabinol

Kanyo, R.; Amin, M. R.; Locskai, L. F.; Bouvier, D. D.; Olthuis, A. M.; Allison, W. T.; Ali, D. W.

10.1101/2021.01.04.425279 — pharmacology and toxicology — Posted on 2021-03-03

4448 Ablating Ku70 phosphorylation results in defective DNA damage repair and spontaneous induction of hepatocellular carcinoma

Saha, J.; Bae, J.; Wang, S.-y.; Chappell, L. J.; Gopal, P.; Davis, A. J.

10.1101/2021.03.03.433432 — cancer biology — Posted on 2021-03-03

4449 MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions

Backx, E.; Wauters, E.; Baldan, J.; Van Bulck, M.; Michiels, E.; Heremans, Y.; De Paep, D. L.; Bouwens, L.; Goyama, S.; Kurokawa, M.; Jacquemin, P.; Houbracken, I.; Rooman, I.

10.1101/2020.08.21.260539 — cancer biology — Posted on 2021-03-03

4450 SUMOylation of GMFB regulates the stability and function of GMF in RPE cells under oxidative stress and inflammation

Sun, W.; Wang, J.; Zhang, J.; Gao, F.; Ou, Q.; Tian, H.; Jin, C.; Xu, J.; Zhang, J.; Huang, J.; Xu, G.-T.; Lu, L.

10.1101/2021.03.03.433763 — biochemistry — Posted on 2021-03-03

4451 Bi-directional protein-protein interactions control liquid-liquid phase separation of PSD-95 and its interaction partners

Christensen, N. R.; Pedersen, C. P.; Sereikaite, V.; Pedersen, J. N.; Vistrup-Parry, M.; Soerensen, A. T.; Otzen, D. E.; Arleth, L.; Teilum, K.; Madsen, K. L.; Stromgaard, K.

10.1101/2021.03.03.433781 — biochemistry — Posted on 2021-03-03

4452 Site-specific phosphorylation of PSD-95 dynamically regulates the post-synaptic density as observed by phase separation

Vistrup-Parry, M.; Chen, X.; Johansen, T.; Bach, S.; Buch-Larsen, S.; Bartling, C.; Ma, C.; Clemmensen, L.; Nielsen, M. L.; Zhang, M.; Stromgaard, K.

10.1101/2021.03.03.433754 — biochemistry — Posted on 2021-03-03

4453 Towards high spatially resolved microproteomics using expansion microscopy

Drelich, L.; Aboulouard, S.; Franck, J.; Salzet, M.; Fournier, I.; Wisztorski, M.

10.1101/2021.03.03.433765 — biochemistry — Posted on 2021-03-03

4454 miQC: An adaptive probabilistic framework for quality control of single-cell RNA-sequencing data

Hippen, A. A.; Falco, M. M.; Weber, L. M.; Erkan, E. P.; Zhang, K.; Doherty, J. A.; Vähärautio, A.; Greene, C. S.; Hicks, S. C.

10.1101/2021.03.03.433798 — genomics — Posted on 2021-03-03

4455 Contribution of epigenetic changes to escape from X-chromosome inactivation

Balaton, B. P.; Brown, C. J.

10.1101/2021.03.03.433635 — genetics — Posted on 2021-03-03

4456 Lamp1 mediates lipid transport, but is dispensable for autophagy in Drosophila

Chaudrhy, N.; Sica, M.; Surabhi, S.; Sanchez Hernandez, D.; Mesquita, A.; Selimovic, A.; Riaz, A.; Bai, H.; Macintosh, G. C.; Jenny, A.

10.1101/2021.03.03.432938 — cell biology — Posted on 2021-03-03

4457 Interstitial leukocyte navigation through a search and run response to gradients

Georgantzoglou, A.; Poplimont, H.; Laemmermann, T.; Sarris, M.

10.1101/2021.03.03.433706 — cell biology — Posted on 2021-03-03

4458 High molecular weight DNA extraction strategies for long-read sequencing of complex metagenomes

Trigodet, F.; Lolans, K.; Fogarty, E.; Shaiber, A.; Morrison, H.; Barreiro, L.; Jabri, B.; Eren, A. M.

10.1101/2021.03.03.433801 — microbiology — Posted on 2021-03-03

4459 Pneumococcal genetic variability influences age-dependent bacterial carriage

Kremer, P. H. C.; Ferwerda, B.; Bootsma, H. J.; Rots, N. Y.; Wijmega-Monsuur, A. J.; Sanders, L. A. M.; Trzcinski, K.; Wyllie, A. L.; Turner, P.; van der Ende, A.; Brouwer, M. C.; Bentley, S. D.; van de Beek, D.; Lees, J. A.

10.1101/2021.03.03.433546 — microbiology — Posted on 2021-03-03

4460 Identification of a novel regulator of Clostridioides difficile cortex formation

Touchette, M. H.; Benito de la Puebla, H.; Alves Feliciano, C.; Tanenbaum, B.; Schenone, M.; Carr, S.; Shen, A.

10.1101/2021.03.03.433760 — microbiology — Posted on 2021-03-03

4461 Exploring the microdiversity within marine bacterial taxa: Towards an integrated biogeography in the Southern Ocean

Schwob, G.; Segovia, N.; Gonzalez-Wevar, C.; Cabrol, L.; Orlando, J.; Poulin, E. A.

10.1101/2021.03.03.433356 — microbiology — Posted on 2021-03-03

4462 Dissecting CD8+ T cell pathology of severe SARS-CoV-2 infection by single-cell epitope mapping

Schreibing, F.; Hannani, M.; Ticconi, F.; Fewings, E.; Nagai, J. S.; Begemann, M.; Kuppe, C.; Kurth, I.; Kranz, J.; Frank, D.; Anslinger, T. M.; Ziegler, P.; Kraus, T.; Enczmann, J.; Balz, V.; Windhofer, F.; Balfanz, P.; Kurts, C.; Marx, G.; Marx, N.; Dreher, M.; Schneider, R. K.; Saez-Rodriguez, J.; Costa Filho, I. G.; Kramann, R.

10.1101/2021.03.03.432690 — immunology — Posted on 2021-03-03

4463 Maturation signatures of conventional dendritic cells in COVID-19 reflect direct viral sensing

Marongiu, L.; Protti, G.; Facchini, F. A.; Valache, M.; Mingozzi, F.; Ranzani, V.; Putignano, A. R.; Salviati, L.; Bevilacqua, V.; Curti, S.; Crosti, M.; D'Angio, M.; Bettini, L. R.; Biondi, A.; Nespoli, L.; Tamini, N.; Mancini, N.; Clementi, N.; Abrignani, S.; Spreafico, R.; Granucci, F.

10.1101/2021.03.03.433597 — immunology — Posted on 2021-03-03

4464 A new triple fluorescence reporter system for discrimination of Apobec1 and Apobec3 C-to-U RNA editing activities and editing-dependent protein expression

Schweissthal, B.; Brunken, K.; Brach, J.; Emde, L.; Hetsch, F.; Fricke, S.; Meier, J. C.

10.1101/2021.03.03.433736 — neuroscience — Posted on 2021-03-03

4465 Genome-wide analysis of focal DNA hypermethylation in IDH-mutant AML samples

Wilson, E. R.; Helton, N.; Heath, S. E.; Fulton, R. S.; Miller, C.; Payton, J. E.; Welch, J. S.; Walter, M.; Westervelt, P.; DiPersio, J. F.; Link, D. C.; Ley, T. J.; Spencer, D. H.

10.1101/2021.03.03.433799 — cancer biology — Posted on 2021-03-03

4466 Structures of ABCG2 under turnover conditions reveal a key step in drug transport mechanism

Yu, Q.; Ni, D.; Kowal, J.; Manolaridis, I.; Jackson, S. M.; Stahlberg, H.; Locher, K. P.

10.1101/2021.03.03.433600 — biophysics — Posted on 2021-03-03

4467 Novel anti-repression mechanism of H-NS proteins by a phage "early protein".

Ben Bdira, F.; Qing, L.; Volkov, A. N.; Lippa, A. M.; Erkelens, A. M.; Bowring, N.; Boyle, A. L.; Ubbink, M.; Dove, S. L.; Dame, R. T.

10.1101/2021.03.03.433722 — biochemistry — Posted on 2021-03-03

4468 A Machine Learning Approach to Unmask Novel Gene Signatures and Prediction of Alzheimers Disease Within Different Brain Regions.

Sharma, A.; Dey, P.

10.1101/2021.03.03.433689 — genomics — Posted on 2021-03-03

4469 Identification of in vivo CFTR conformations during biogenesis and upon misfolding by covalent protein painting (CPP)

Pankow, S.; Bamberger, C.; Martinez-Bartolome, S.; Park, S. K.; Yates, J. R.

10.1101/2021.03.02.433670 — molecular biology — Posted on 2021-03-03

4470 Genome-wide identification of genetic requirements of Pseudomonas aeruginosa PAO1 for rat cardiomyocyte (H9C2) infection by insertion sequencing

Ranjani, J.; Sivakumar, R.; Gunasekaran, P.; Rajendhran, J.

10.1101/2021.03.03.433694 — microbiology — Posted on 2021-03-03

4471 Identification and quantification of SARS-CoV-2 leader subgenomic mRNA gene junctions in nasopharyngeal samples shows phasic transcription in animal models of COVID-19 and aberrant pattens in humans

Penrice-Randal, R.; Goldswain, H.; Prince, T.; Randle, N.; Salguero, J.; Tree, J.; Vamos, E.; Nelson, C.; ISARIC-4C Investigators, ; COG-UK Consortium, ; Stewart, J. P.; Matthews, D. A.; Carroll, M.; Darby, A.; Hiscox, J. A.

10.1101/2021.03.03.433753 — microbiology — Posted on 2021-03-03

4472 Human cortical dynamics during full-body heading changes

Gramann, K.; Hohlefeld, F. U.; Gehrke, L.; Klug, M.

10.1101/417972 — neuroscience — Posted on 2021-03-03

4473 Extensive structural remodeling of the axonal arbors of parvalbumin basket cells during development

Micheva, K. D.; Kiraly, M.; Perez, M. M.; Madison, D. V.

10.1101/2021.03.03.433691 — neuroscience — Posted on 2021-03-03

4474 Evidence for microbiome-dependent chilling tolerance in Sorghum

Erlandson, S.; Bheemanahalli, R.; Johnson, M.; Narayana, N. K.; Graham, C.; Jagadish, K.; Subramanian, S.

10.1101/2021.03.02.433195 — plant biology — Posted on 2021-03-03

4475 An updated assembly strategy helps parsing the cryptic mitochondrial genome evolution in plants

Feng, Y.; Xiang, X.; Fu, Z.; Jin, X.

10.1101/2021.03.02.433321 — evolutionary biology — Posted on 2021-03-03

4476 Comparative Population Genetics in the Human Gut Microbiome

Shoemaker, W. R.; Chen, D.; Garud, N. R.

10.1101/2021.03.02.433642 — evolutionary biology — Posted on 2021-03-03

4477 Development and Validation of LAMP Primer Sets for Rapid and Correct Identification of Aspergillus fumigatus Carrying the cyp51A TR46 Azole Resistance Gene

Trabasso, P.; Matsuzawa, T.; Arai, T.; Hagiwara, D.; Mikami, Y.; Moretti, M. L.; Watanabe, A.

10.1101/2021.03.02.433685 — molecular biology — Posted on 2021-03-03

4478 Tetraspanin immunocapture phenotypes extracellular vesicles according to biofluid source but may limit identification of multiplexed cancer biomarkers

Mizenko, R. R.; Brostoff, T.; Rojalin, T.; Koster, H. J.; Swindell, H. S.; Leiserowitz, G. S.; Wang, A.; Carney, R. P.

10.1101/2021.03.02.433595 — molecular biology — Posted on 2021-03-03

4479 A Dose-Response Model and D10-Value for Mycobacterium tuberculosis Exposed to Dosimetrically Verified Ionizing Radiation

Watkins, J. V.; Bell, J.; Knabenbauer, P.; Brandl, A.; Dobos, K. M.

10.1101/2021.03.02.433681 — microbiology — Posted on 2021-03-03

4480 Adaptive ecological processes and metabolic independence drive microbial colonization and resilience in the human gut

Watson, A. R.; Fuessel, J.; Veseli, I.; DeLongchamp, J. Z.; Silva, M.; Trigodet, F.; Lolans, K.; Shaiber, A.; Fogarty, E.; Quince, C.; Yu, M. K.; Soylev, A.; Morrison, H. G.; Lee, S. T. M.; Rubin, D. T.; Jabri, B.; Louie, T.; Eren, A. M.

10.1101/2021.03.02.433653 — microbiology — Posted on 2021-03-03

4481 Genomic evaluation of Bordetella spp. originating from Australia

Fong, W.; Timms, V.; Sim, E.; Sintchenko, V.

10.1101/2021.03.02.433639 — microbiology — Posted on 2021-03-03

4482 Urequinona, a molecule from the root of Pentalinon andrieuxii Muell-Arg heals Leishmania mexicana ear{acute}s infection in mice: This plant is widely used by the Mayan traditional medicine.

Lezama-Davila, C. M.; Isaac-Marquez, A. P.

10.1101/2021.03.02.433683 — microbiology — Posted on 2021-03-03

4483 A positive role of task-deactivated default mode network in narrative speech comprehension

Liu, L.; Li, H.; Ren, Z.; Zhou, Q.; Zhang, Y.; Lu, C.; Qiu, J.; Chen, H.; Ding, G.

10.1101/2021.03.02.433669 — neuroscience — Posted on 2021-03-03

4484 Distributed context-dependent choice information in mouse dorsal-parietal cortex

Orlandi, J. G.; Abdolrahmani, M.; Aoki, R.; Lyamzin, D. R.; Benucci, A.

10.1101/2021.03.02.433657 — neuroscience — Posted on 2021-03-03

4485 Resilience through diversity: Loss of neuronal heterogeneity in epileptogenic human tissue renders neural networks more susceptible to sudden changes in synchrony

Rich, S.; Moradi Chameh, H.; Lefebvre, J.; Valiante, T. A.

10.1101/2021.03.02.433627 — neuroscience — Posted on 2021-03-03

4486 Independent and distinct patterns of abnormal lateral orbitofrontal cortex activity during compulsive grooming and reversal learning normalize after fluoxetine

Manning, E. E.; Geramita, M. A.; Piantadosi, S. C.; Ahmari, S. E.

10.1101/2021.03.02.433664 — neuroscience — Posted on 2021-03-03

4487 Mechanisms Underlying Economic Revealed Preference Of Multi-Component Bundles In Primate Orbitofrontal Cortex

Pastor-Bernier, A.; Schultz, W.

10.1101/2021.03.02.433629 — neuroscience — Posted on 2021-03-03

4488 Apparent digestibility of captive colobines in relation to stomach types with special reference to fibre digestion

Hoshino, S.; Seino, S.; Funahashi, T.; Hoshino, T.; Clauss, M.; Matsuda, I.; Yayota, M.

10.1101/2021.03.02.433677 — zoology — Posted on 2021-03-03

4489 Tipping-point analysis uncovers critical transition signals from gene expression profiles

Yang, X. H.; Wang, Z.; Goldstein, A.; Sun, Y.; Griggs, D.; Feliciano, A.; Wang, Y.; Cunningham, J.

10.1101/668442 — systems biology — Posted on 2021-03-03

4490 Murine deficiency of peroxisomal L-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis

Ranea-Robles, P.; Violante, S.; Argmann, C.; Dodatko, T.; Bhattacharya, D.; Chen, H.; Yu, C.; Friedman, S. L.; Puchowicz, M.; Houten, S.

10.1101/2021.03.02.433634 — physiology — Posted on 2021-03-03

4491 Geroprotective effects of Aronia melanocarpa fruit extract on Drosophila melanogaster

Platonova, E.; Shaposhnikov, M.; Zemskaya, N.; Golubev, D.; Kukuman, D.; Pakshina, N.; Ulyasheva, N.; Punegov, V.; Patov, S.; Moskalev, A.

10.1101/2021.03.03.433673 — pharmacology and toxicology — Posted on 2021-03-03

4492 YAP1 induces invadopodia formation by transcriptionally activating TIAM1 through its enhancer in breast cancer

Shen, J.; Huang, Q.; Feng, S.; Jia, W.; Liu, L.; Li, X.; Tao, D.; Xie, D.

10.1101/2021.03.02.431738 — cancer biology — Posted on 2021-03-03

4493 Ribovirus classification by a polymerase barcode sequence

Babaian, A.; Edgar, R. C.

10.1101/2021.03.02.433648 — bioinformatics — Posted on 2021-03-03

4494 The complete mitochondrial genome of a parthenogenetic ant, Monomorium triviale (Hymenoptera: Formicidae)

Idogawa, N.; Lee, C.-C.; Yang, C.-C. S.; Dobata, S.

10.1101/2021.03.02.433554 — genomics — Posted on 2021-03-03

4495 Liquid and vapor-phase antifungal activities of natural borneol against Candida albicans and its germ tube formation

Wang, Y.; Liu, H.

10.1101/2021.03.02.433682 — microbiology — Posted on 2021-03-03

4496 Exploring bacterial diversity via a curated and searchable snapshot of archived DNA sequences

Blackwell, G. A.; Hunt, M.; Malone, K. M.; Lima, L.; Horesh, G.; Alako, B. T. F.; Thomson, N. R.; Iqbal, Z.

10.1101/2021.03.02.433662 — microbiology — Posted on 2021-03-03

4497 Recombinant protein subunit SARS-CoV-2 vaccines formulated with CoVaccine HT adjuvant induce broad, Th1 biased, humoral and cellular immune responses in mice

Lai, C.-Y.; To, A.; Wong, T. A. S.; Lieberman, M. M.; Clements, D. E.; Senda, J. T.; Ball, A. H.; Pessaint, L.; Andersen, H.; Donini, O.; Lehrer, A. T.

10.1101/2021.03.02.433614 — immunology — Posted on 2021-03-03

4498 Altered Sub-Genomic RNA Expression in SARS-CoV-2 B.1.1.7 Infections

Parker, M. D.; Lindsey, B. B.; Shah, D. R.; Hsu, S.; Keeley, A. J.; Partridge, D. G.; Leary, S.; Cope, A.; State, A.; Johnson, K.; Ali, N.; Raghei, R.; Heffer, J.; Smith, N.; Zhang, P.; Gallis, M.; Louka, S. F.; Whiteley, M.; Foulkes, B. H.; Christou, S.; Wolverson, P.; Pohare, M.; Hansford, S. E.; Green, L. R.; Evans, C.; Raza, M.; Wang, D.; Gaudieri, S.; Mallal, S.; The COVID-19 Genomics UK (COG-UK) consortium, ; de Silva, T. I.

10.1101/2021.03.02.433156 — genomics — Posted on 2021-03-03

4499 Regulation of apical constriction via microtubule- and Rab11-dependent apical transport during tissue invagination

Le, T. P.; Chung, S.

10.1101/827378 — developmental biology — Posted on 2021-03-03

4500 Low-dose lung radiotherapy for COVID-19 lung disease: a pre-clinical efficacy study in a bleomycin model of pneumonitis.

Jackson, M. R.; Stevenson, K.; Chahal, S. K.; Curley, E.; Finney, G.; Gutierrez-Quintana, R.; Onwubiko, E.; Rupp, A. F.; Strathdee, K.; MacLeod, M. K.; McSharry, C.; Chalmers, A. J.

10.1101/2021.03.03.433704 — immunology — Posted on 2021-03-03

4501 Neutralizing IFNL3 Autoantibodies in Severe COVID-19 Identified Using Molecular Indexing of Proteins by Self-Assembly

Credle, J. J.; Gunn, J.; Sangkhapreecha, P.; Monaco, D. R.; Zheng, X. A.; Tsai, H.-J.; Wilbon, A.; Morgenlander, W. R.; Dong, Y.; Jayaraman, S.; Tosi, L.; Parekkadan, B.; Baer, A. N.; Roederer, M.; Bloch, E. M.; Tobian, A. A. R.; Zyskind, I.; Silverberg, J. I.; Rosenberg, A. Z.; Cox, A. L.; Lloyd, T.; Mammen, A. L.; Larman, H. B.

10.1101/2021.03.02.432977 — immunology — Posted on 2021-03-03

4502 Blockade of SARS-CoV-2 infection in-vitro by highly potent PI3K-α/mTOR/BRD4 inhibitor

Acharya, A.; Pandey, K.; Thurman, M.; Challagundla, K. B.; Vann, K. R.; Kutateladze, T. G.; Morales, G. A.; Durden, D. L.; Byrareddy, S. N.

10.1101/2021.03.02.433604 — pharmacology and toxicology — Posted on 2021-03-03

4503 A pharmacophore model for SARS-CoV-2 3CLpro small molecule inhibitors and in vitro experimental validation of computationally screened inhibitors

Glaab, E.; Manoharan, G. B.; Abankwa, D.

10.1101/2021.03.02.433618 — bioinformatics — Posted on 2021-03-03

4504 Functional interdependence of the actin nucleator Cobl and Cobl-like in dendritic arbor development

Izadi, M.; Seemann, E.; Schlobinski, D.; Schwintzer, L.; Qualmann, B.; Kessels, M. M.

10.1101/2021.03.03.433715 — cell biology — Posted on 2021-03-03

4505 Enabling single-molecule localization microscopy in turbid food emulsions

Jabermoradi, A.; Yang, S.; Gobes, M.; Duynhoven, van, J.; Hohlbein, J.

10.1101/2021.03.03.433739 — biophysics — Posted on 2021-03-03

4506 Competitive binding of MatP and topoisomerase IV to the MukB dimerization hinge

Fisher, G.; Bolla, J. R.; Rajasekar, K.; makela, j.; baker, r.; zhou, m.; prince, j.; Stracy, M.; Robinson, C. V.; Arciszewska, L. K.; Sherratt, D.

10.1101/2021.03.03.433707 — biochemistry — Posted on 2021-03-03

4507 Targeting Biofilm of MDR Providencia stuartii by Phages Using a Catheter Model

Rakov, C.; Ben-Porat, S.; Alkalay-Oren, S.; Yerushalmy, O.; Abdalrhman, M.; Gronovich, N.; Huang, L. S.; Pride, D. T.; Coppenhagen-Glazer, S.; Nir Paz, R.; Hazan, R.

10.1101/2021.03.02.433687 — microbiology — Posted on 2021-03-03

4508 Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state

Cao, A.-M.; Quast, R. B.; Fatemi, F.; Rondard, P.; Pin, J.-P.; Margeat, E.

10.1101/2021.01.05.424557 — biophysics — Posted on 2021-03-03

4509 Signatures of Discriminative Copy Number Aberrations in 31 Cancer Subtypes

Gao, B.; Baudis, M.

10.1101/2020.12.18.423278 — bioinformatics — Posted on 2021-03-03

4510 Towards a global investigation of transcriptomic signatures through co-expression networks and pathway knowledge for the identification of disease mechanisms

Figueiredo, R. Q.; Raschka, T.; Kodamullil, A. T.; Apitius, M. H.; Mubeen, S.; Domingo-Fernandez, D.

10.1101/2021.03.02.433520 — bioinformatics — Posted on 2021-03-03

4511 The histone variant H2A.W and linker histone H1 co-regulate heterochromatin accessibility and DNA methylation

Bourguet, P.; Picard, C. L.; Yelagandula, R.; Pelissier, T.; Lorkovic, Z. J.; Feng, S.; Pelissier, M.-N.; Schmücker, A.; Jacobsen, S. E.; Berger, F.; Mathieu, O.

10.1101/2020.03.19.998609 — genomics — Posted on 2021-03-03

4512 A benchmarking of human mitochondrial DNA haplogroup classifiers from whole-genome and whole-exome sequence data

Garcia-Olivares, V.; Munoz-Barrera, A.; Lorenzo-Salazar, J. M.; Zaragoza-Trello, C.; Rubio-Rodriguez, L. A.; Diaz-de Usera, A.; Jaspez, D.; Inigo-Campos, A.; Gonzalez-Montelongo, R.; Flores, C.

10.1101/2021.02.11.430775 — genomics — Posted on 2021-03-03

4513 Handcuffing intrinsically disordered regions in Mlh1-Pms1 disrupts mismatch repair

Furman, C. M.; Wang, T.-Y.; Zhao, Q.; Yugandhar, K.; Yu, H.; Alani, E.

10.1101/2021.03.02.433678 — genetics — Posted on 2021-03-03

4514 Simulation of bacterial populations with SLiM

Cury, J.; Haller, B. C.; Achaz, G.; Jay, F.

10.1101/2020.09.28.316869 — evolutionary biology — Posted on 2021-03-03

4515 Joint species distributions reveal the combined effects of host plants, abiotic factors and species competition as drivers of species abundances in fruit flies

Facon, B.; Hafsi, A.; Charlery, M.; Robin, S.; Massol, F.; Dubart, M.; Chiquet, J.; Frago, E.; Chiroleu, F.; Duyck, P.-F.; Ravigne, V.

10.1101/2020.12.07.414326 — ecology — Posted on 2021-03-03

4516 Plant provenance affects pollinator network: implications for ecological restoration

Bucharova, A.; Lampei, C.; Conrady, M.; May, E.; Matheja, J.; Meyer, M.; Ott, D.

10.1101/2020.11.26.399493 — ecology — Posted on 2021-03-03

4517 Discovery of a small molecule having both potent anti-fibrotic and anti-inflammatory capabilities

Kim, H.-S.; Meang, M. K.; Kim, S.; Lee, J. Y.; Seong, B.; Kim, I.-H.; Youn, B.-S.

10.1101/770404 — cell biology — Posted on 2021-03-03

4518 Reverse complementary matches simultaneously promote both back-splicing and exon-skipping

Cao, D.

10.1101/2021.02.28.433292 — molecular biology — Posted on 2021-03-03

4519 Zika virus hijacks extracellular vesicle tetraspanin pathways for cell-to-cell transmission

York, S. B.; Sun, L.; Cone, A. S.; Duke, L. C.; Cheerathodi, M.; Meckes, D. G.

10.1101/2021.03.02.433679 — microbiology — Posted on 2021-03-03

4520 Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist

Pickford, P.; Lucey, M.; Rujan, R.-M.; McGlone, E. R.; Bitsi, S.; Ashford, F.; Correa, I. R.; Hodson, D.; Tomas, A.; Deganutti, G.; Reynolds, C. A.; Owen, B. M.; Tan, T. M.; Minnion, J.; Bloom, S. R.; Jones, B.

10.1101/2021.03.02.433157 — pharmacology and toxicology — Posted on 2021-03-03

4521 Ribosomal RNA methylation by GidB is a capacitor for discrimination of mischarged tRNA

Bi, Z.; Su, H.; Hong, J.; Javid, B.

10.1101/2021.03.02.433644 — molecular biology — Posted on 2021-03-03

4522 Atorvastatin effectively inhibits late replicative cycle steps of SARS-CoV-2 in vitro

Zapata-Cardona, M. I.; Florez-Alvarez, L.; Zapata-Builes, W.; Guerra-Sandoval, A.; Guerra-Almonacid, C.; Hincapie-Garcia, J.; Rugeles, M. T.; Hernandez, J. C.

10.1101/2021.03.01.433498 — microbiology — Posted on 2021-03-03

4523 Microglia show differential transcriptomic response to Aβ peptide aggregates ex vivo and in vivo

McFarland, K. N.; Ceballos, C.; Rosario, A.; Ladd, T. B.; Moore, B. D.; Golde, G.; Wang, X.; Allen, M.; Ertekin-Taner, N.; Funk, C. C.; Robinson, M.; Baloni, P.; Rappaport, N.; Chakrabarty, P.; Golde, T.

10.1101/2021.03.02.433544 — neuroscience — Posted on 2021-03-03

4524 On the capacity of putative plant odorant-binding proteins to bind volatile plant isoprenoids

Giordano, D.; Facchiano, A.; D'Auria, S.; Loreto, F.

10.1101/2021.03.02.433599 — plant biology — Posted on 2021-03-03

4525 Metatranscriptomic comparison of endophytic and pathogenic Fusarium-Arabidopsis interactions reveals plant transcriptional plasticity

Guo, L.; Yu, H.; Wang, B.; Vescio, K.; DeIulio, G. A.; Yang, H.; Berg, A.; Zhang, L.; Edel-Hermann, V.; Steinberg, C.; Kistler, H. C.; Ma, L.-J.

10.1101/2021.03.01.433437 — plant biology — Posted on 2021-03-03

4526 PP2A/B55α substrate recruitment as defined by the retinoblastoma-related protein p107

Fowle, H.; Zhao, Z.; Xu, Q.; Wang, X.; Adeyemi, M.; Feiser, F.; Kurimchak, A.; Kettenbach, A. N.; Page, R.; Peti, W.; Dunbrack, R. L.; Grana, X.

10.1101/2021.03.02.433577 — biochemistry — Posted on 2021-03-03

4527 Methylation-mediated retuning on the enhancer-to-silencer activity scale of networked regulatory elements guides driver-gene misregulation

Edrei, Y.; Levy, R.; Marom, A.; Radlwimmer, B.; Hellman, A.

10.1101/2021.03.02.433521 — genomics — Posted on 2021-03-03

4528 Limited selection towards lighter seeds in Danish grasslands over an eight-year period

Damgaard, C.

10.1101/2021.03.02.433513 — ecology — Posted on 2021-03-02

4529 Widespread translational control regulates retinal development in mouse

Chen, K.; Chen, C.; Li, H.; Yang, J.; Xiang, M.; Wang, H.; Xie, Z.

10.1101/2021.03.02.433656 — developmental biology — Posted on 2021-03-02

4530 PEG10 viral aspartic protease domain is essential for the maintenance of fetal capillary structure in the mouse placenta

Shiura, H.; Ono, R.; Tachibana, S.; Kohda, T.; Kaneko-Ishino, T.; Ishino, F.

10.1101/2021.03.02.433660 — developmental biology — Posted on 2021-03-02

4531 A pro-endocrine pancreatic transcriptional program established during development is retained in human gallbladder epithelial cells

Joglekar, M. V.; Sahu, S.; Wong, W. K. M.; Satoor, S. N.; Dong, C. X.; Farr, R. J.; Williams, M. D.; Pandya, P.; Jhala, G.; Yang, S. N. Y.; Chew, Y. V.; Hetherington, N.; Thiruchevlam, D.; Mitnala, S.; Rao, G. V.; Reddy, D. N.; Loudovaris, T.; Hawthorne, W. J.; Elefanty, A. G.; Joglekar, V. M.; Stanley, E. G.; Martin, D.; Thomas, H. E.; Tosh, D.; Dalgaard, L. T.; Hardikar, A. A.

10.1101/2021.03.02.433636 — developmental biology — Posted on 2021-03-02

4532 Cholecystokinin Suppresses β-Cell Apoptosis, Including in Human Islets in a Transplant Model

Kim, H. T.; de Souza, A. H.; Umhoefer, H.; Han, J.; Anzia, L.; Sacotte, S. J.; Williams, R. A.; Blumer, J. T.; Bartosiak, J. T.; Fontaine, D. A.; Baan, M.; Kibbe, C. R.; Davis, D. B.

10.1101/2021.03.02.433645 — cell biology — Posted on 2021-03-02

4533 Structural basis of LhcbM5-mediated state transitions in green algae

Pan, X.; Tokutsu, R.; Li, A.; Takizawa, K.; Song, C.; Murata, K.; Yamasaki, T.; Liu, Z.; Minagawa, J.; Li, M.

10.1101/2021.03.02.433643 — plant biology — Posted on 2021-03-02

4534 RaptGen: A variational autoencoder with profile hidden Markov model for generative aptamer discovery

Iwano, N.; Adachi, T.; Aoki, K.; Nakamura, Y.; Hamada, M.

10.1101/2021.02.17.431338 — bioinformatics — Posted on 2021-03-02

4535 Molecular Assays of Pollen Use Consistently Reflect Pollinator Visitation Patterns in a System of Flowering Plants

James, A. R. M.; Geber, M. A.; Toews, D. P. L.

10.1101/2020.04.14.041814 — ecology — Posted on 2021-03-02

4536 Hematopoietic progenitors passing through early embryonic CD4-positive stage are long-lived and give rise to myeloid and lymphoid progeny

Apostolov, A. K.; Marie, J. C.

10.1101/2021.03.02.433212 — developmental biology — Posted on 2021-03-02

4537 Title - Impact of extrinsic incubation temperature on natural selection during Zika virus infection of Aedes aegypti

Murrieta, R.; Garcia-Luna, S. M.; Murrieta, D. J.; Halladay, G.; Young, M. C.; Fauver, J. R.; Gendernalik, A.; Weger-Lucarelli, J.; Rückert, C.; Ebel, G.

10.1101/2021.03.02.433538 — microbiology — Posted on 2021-03-02

4538 Human parvovirus B19 interacts with globoside under acidic conditions as an essential step in endocytic trafficking

Bieri, J.; Leisi, R.; Bircher, C.; Ros, C.

10.1101/2021.03.02.433539 — microbiology — Posted on 2021-03-02

4539 Prostaglandin analog effects on cerebrospinal fluid reabsorption via nasal mucosa

Pedler, M. G.; Petrash, J. M.; Subramanian, P. S.

10.1101/2021.03.02.433537 — neuroscience — Posted on 2021-03-02

4540 Reduced PTPRD expression differentially alters brain phosphotyrosine phosphoproteomic profiles of 2 and 12 month-old mice

Uhl, G.; Henderson, I. M.; Martinez, M.; Stokes, M.

10.1101/2021.03.02.433536 — neuroscience — Posted on 2021-03-02

4541 Slow, heterogeneous NFκB single molecule conformational dynamics and implications for function

Chen, W.; Liu, W.; Wolynes, P. G.; Komives, E. A.

10.1101/2021.03.02.433616 — biophysics — Posted on 2021-03-02

4542 Non-canonical function of the Sex-lethal gene controls the protogyny phenotype in Drosophila melanogaster

Seong, K.-H.; Kang, S.

10.1101/2021.03.02.433534 — genetics — Posted on 2021-03-02

4543 Spatio-temporal modelling for the evaluation of an altered Indian saline Ramsar site and its drivers for ecosystem management and restoration

NAIK, R.; SHARMA, L.

10.1101/2021.03.02.433535 — ecology — Posted on 2021-03-02

4544 Somatic piRNAs and Transposons are Differentially Regulated During Skeletal Muscle Atrophy and Programmed Cell Death

Tsuji, J.; Thomson, T.; Brown, C.; Ghosh, S.; Theurkauf, W.; Weng, Z.; Schwartz, L. M.

10.1101/2021.03.02.433533 — developmental biology — Posted on 2021-03-02

4545 Opposing motors provide mechanical and functional robustness in the human spindle

Neahring, L.; Cho, N. H.; Dumont, S.

10.1101/2021.03.02.433652 — cell biology — Posted on 2021-03-02

4546 Mutually opposing activity of PIN7 splicing isoforms is required for auxin-mediated tropic responses in Arabidopsis thaliana

Kashkan, I.; Hrtyan, M.; Retzer, K.; Humpolickova, J.; Jayasree, A.; Filepova, R.; Vondrakova, Z.; Hejatko, J.; Simon, S.; Rombaut, D.; Jacobs, T. B.; Frilander, M. J.; Friml, J.; Petrasek, J.; Ruzicka, K.

10.1101/2020.05.02.074070 — plant biology — Posted on 2021-03-02

4547 Progranulin promotes immune evasion of pancreatic adenocarcinoma through regulation of MHCI expression

Cheung, P. F.; Yang, J.; Krengel, K.; Althoff, K.; Yip, C.; Siu, E. H.; Ng, L. W.; Lang, K. S.; Cham, L.; Engel, D. R.; Soun, C.; Cima, I.; Scheffler, B.; Striefler, J. K.; Sinn, M.; Bahra, M.; Pelzer, U.; Oettle, H.; Markus, P.; Smeets, E. M.; Aarntzen, E. H.; Savvatakis, K.; Liffers, S.-T.; Neander, C.; Bazarna, A.; Zhang, X.; Merkler, D.; Paschen, A.; Crawford, H. C.; Chan, A. W.; Cheung, S. T.; Siveke, J. T.

10.1101/2021.02.24.432700 — cancer biology — Posted on 2021-03-02

4548 Confirmation bias optimizes reward learning

Tarantola, T.; Folke, T.; Boldt, A.; Perez, O. D.; De Martino, B.

10.1101/2021.02.27.433214 — animal behavior and cognition — Posted on 2021-03-02

4549 Still no evidence for disruption of global patterns of nest predation in shorebirds

Bulla, M.; Valcu, M.; Kempenaers, B.

10.1101/2021.02.17.431576 — ecology — Posted on 2021-03-02

4550 Pou5f3 and Sox19b determine gene expression repertoire at Zygotic Genome Activation

Gao, M.; Veil, M.; Rosenblatt, M.; Gebhard, A.; Hass, H.; Buryanova, L.; Yampolsky, L.; Gruening, B. A.; Ulianov, S. V.; Timmer, J.; Onichtchouk, D.

10.1101/2020.02.16.949362 — developmental biology — Posted on 2021-03-02

4551 Desmosomes polarize mechanical signaling to govern epidermal tissue form and function

Broussard, J. A.; Koetsier, J. L.; Hegazy, M.; Green, K. J.

10.1101/2020.01.21.914176 — cell biology — Posted on 2021-03-02

4552 The Mechanism of Neurite Outgrowth Induction by Novel Synthetic Retinobenzoic Acids

Zhang, Y.; Yoshimi, Y.; Funatsu, O.; Hayashi, R.; Komagawa, S.; Saito, S.; Nagahara, Y.; Ikekita, M.

10.1101/2021.03.01.429320 — cell biology — Posted on 2021-03-02

4553 Cytoplasmic domain and enzymatic activity of ACE2 is not required for PI4KB dependent endocytosis entry of SARS-CoV-2 into host cells

Yang, H.; Zhao, x.; xun, M.; Xu, L.; Liu, B.; Wang, H.

10.1101/2021.03.01.433503 — microbiology — Posted on 2021-03-02

4554 Vertical inheritance governs biosynthetic gene cluster evolution and chemical diversification

Chase, A. B.; Sweeney, D.; Muskat, M. N.; Guillen-Matus, D.; Jensen, P. R.

10.1101/2020.12.19.423547 — microbiology — Posted on 2021-03-02

4555 MEG Oscillatory and Aperiodic neural dynamics contribute to different cognitive aspects of short-term memory decline through the lifespan

Thuwal, K.; Banerjee, A.; Roy, D.

10.1101/2021.03.02.433594 — neuroscience — Posted on 2021-03-02

4556 Daily changes in neuronal activities of the dorsal motor nucleus of the vagus under standard and short-term high fat diet - implications for circadian modulation of parasympathetic outflow

Chrobok, L.; Klich, J. D.; Jeczmien-Lazur, J. S.; Pradel, K.; Palus-Chramiec, K.; Sanetra, A. M.; Piggins, H. D.; Lewandowski, M. H.

10.1101/2021.03.02.433571 — neuroscience — Posted on 2021-03-02

4557 Dopamine differentially modulates the size of projection neuron ensembles in the intact and dopamine-depleted striatum

Maltese, M.; March, J. R.; Bashaw, A. G.; Tritsch, N. X.

10.1101/865006 — neuroscience — Posted on 2021-03-02

4558 Evolution of the bread wheat D-subgenome and enriching it with diversity from Aegilops tauschii

Gaurav, K.; Arora, S.; Silva, P.; Sanchez-Martin, J.; Horsnell, R.; Gao, L.; Brar, G. S.; Widrig, V.; Raupp, J.; Singh, N.; Wu, S.; Kale, S. M.; Chinoy, C.; Nicholson, P.; Quiroz-Chavez, J.; Simmonds, J.; Hayta, S.; Smedley, M. A.; Harwood, W.; Pearce, S.; Gilbert, D.; Kangara, N.; Gardener, C.; Forner-Martinez, M.; Liu, J.; Yu, G.; Boden, S.; Pascuccci, A.; Ghosh, S.; Hafeez, A. N.; O'Hara, T.; Waites, J.; Cheema, J.; Steuernagel, B.; Patpour, M.; Justesen, A. F.; Liu, S.; Rudd, J.; Avni, R.; Sharon, A.; Steiner, B.; Kirana, R. P.; Buerstmayr, H.; Mehrabi, A. A.; Nasyrova, F. Y.; Chayut, N.;

10.1101/2021.01.31.428788 — plant biology — Posted on 2021-03-02

4559 Serum and sputum MMP-9/TIMP-1 in winter sports athletes and swimmers: relationships with airway function

Bougault, V.; Turmel, J.; Boulet, L.-P.

10.1101/2021.02.10.430578 — physiology — Posted on 2021-03-02

4560 Molecular phenotyping of breast cancer cell lines at the single-cell level for automated cancer diagnosis and prediction of drug sensitivity

Gambardella, G.; Viscido, G.; Tumaini, B.; Isacchi, A.; Bosotti, R.; di Bernardo, D.

10.1101/2021.03.02.433590 — cancer biology — Posted on 2021-03-02

4561 Tumor-Antagonizing Fibroblasts Secrete Prolargin as Tumor Suppressor in Hepatocellular Carcinoma

Chiavarina, B.; Ronca, R.; Otaka, Y.; Sutton, R. B.; Rezzola, S.; Yokobori, T.; Chiodelli, P.; Souche, R.; Maraver, A.; Faa, G.; Oyama, T.; Gofflot, S.; Bellahcene, A.; Detry, O.; Delvenne, P.; Castronovo, V.; Nishiyama, M.; Turtoi, A.

10.1101/2021.01.04.425182 — cancer biology — Posted on 2021-03-02

4562 Mapping densely distributed membrane receptors in blood platelets with expansion microscopy

Heil, H. S.; Aigner, M.; Maier, S.; Goeb, V.; Kusch, C.; Meub, M.; Nieswandt, B.; Stegner, D.; Heinze, K. G.

10.1101/2021.02.16.431449 — biophysics — Posted on 2021-03-02

4563 Optimal transport analysis reveals trajectories in steady-state systems

Zhang, S.; Afanassiev, A.; Greenstreet, L.; Matsumoto, T.; Schiebinger, G.

10.1101/2021.03.02.433630 — bioinformatics — Posted on 2021-03-02

4564 Whole-cell segmentation of tissue images with human-level performance using large-scale data annotation and deep learning

Greenwald, N. F.; Miller, G.; Moen, E.; Kong, A.; Kagel, A.; Fullaway, C. C.; McIntosh, B. J.; Leow, K.; Schwartz, M. S.; Dougherty, T.; Pavelchek, C.; Cui, S.; Camplisson, I.; Bar-Tal, O.; Singh, J.; Fong, M.; Chaudhry, G.; Abraham, Z.; Moseley, J.; Warshawsky, S.; Soon, E.; Greenbaum, S.; Risom, T.; Hollmann, T.; Keren, L.; Graf, W.; Angelo, M.; Van Valen, D.

10.1101/2021.03.01.431313 — bioinformatics — Posted on 2021-03-02

4565 ORT: A workflow linking genome-scale metabolic models with reactive transport codes

Rubinstein, R. L.; Borton, M. A.; Zhou, H.; Shaffer, M.; Hoyt, D. W.; Stegen, J.; Henry, C. S.; Wrighton, K. C.; Versteeg, R.

10.1101/2021.03.02.433463 — bioinformatics — Posted on 2021-03-02

4566 IonQuant enables accurate and sensitive label-free quantification with FDR-controlled match-between-runs

Yu, F.; Haynes, S. E.; Nesvizhskii, A. I.

10.1101/2020.11.02.365437 — bioinformatics — Posted on 2021-03-02

4567 Protein sequence design with a learned potential

Anand-Achim, N.; Eguchi, R. R.; Mathews, I. I.; Perez, C. P.; Derry, A.; Altman, R. B.; Huang, P.

10.1101/2020.01.06.895466 — bioinformatics — Posted on 2021-03-02

4568 Anaerobic Thermophilic Co-digestion of Sugarcane Biorefinery Residues Enhances Biogas Production

Volpi, M. P. C.; de Paiva, L. B. B.; Mockaitis, G.; Rabelo, S. C.; Franco, T. T.; Moraes, B. d. S.

10.1101/2021.02.19.432018 — bioengineering — Posted on 2021-03-02

4569 Development and validation of a cellular host response test as an early diagnostic for sepsis

Guillou, L.; Sheybani, R.; Jensen, A. E.; DiCarlo, D.; Caffery, T.; Thomas, C. B.; Shah, A. M.; Tse, H. T. K.; O'Neal, H. R.

10.1101/2021.02.01.429128 — bioengineering — Posted on 2021-03-02

4570 Inter-tissue convergence of gene expression and loss of cellular identity during ageing

Izgi, H.; Han, D.; Isildak, U.; Huang, S.; Kocabiyik, E.; Khaitovich, P.; Somel, M.; Dönertas, H. M.

10.1101/2021.03.02.432281 — genomics — Posted on 2021-03-02

4571 Exploring the effects of genetic variation on gene regulation in cancer in the context of 3D genome structure

Osman, N.; Shawky, A.-E.-M.; Brylinski, M.

10.1101/2020.10.06.328567 — genomics — Posted on 2021-03-02

4572 The clinical and functional effects of TERT variants in myelodysplastic syndrome

Reilly, C. R.; Myllymaki, M.; Redd, R.; Padmanaban, S.; Karunakaran, D.; Tesmer, V.; Tsai, F. D.; Gibson, C. J.; Rana, H. Q.; Zhong, L.; Saber, W.; Spellman, S. R.; Hu, Z.-H.; Orr, E. H.; Chen, M. M.; De Vivo, I.; Cutler, C.; Antin, J. H.; Neuberg, D.; Garber, J. E.; Nandakumar, J.; Agarwal, S.; Lindsley, R. C.

10.1101/2021.02.11.430624 — genetics — Posted on 2021-03-02

4573 Common variants associated with OSMR expression contribute to carotid plaque vulnerability, but not to cardiovascular disease in humans

van Keulen, D.; van Koeverden, I. D.; Boltjes, A.; Princen, H. M. G.; van Gool, A. J.; de Borst, G. J.; Asselbergs, F. W.; Tempel, D.; Pasterkamp, G.; van der Laan, S. W.

10.1101/576793 — genetics — Posted on 2021-03-02

4574 Ecological opportunity, radiation events and genomic innovations shaped the episodic evolutionary history of papillomaviruses

Willemsen, A.; Bravo, I. G.

10.1101/2020.03.08.982421 — evolutionary biology — Posted on 2021-03-02

4575 Natural Selection as the Sum over all Histories and a Differential Equation for Environmental Coevolution.

Neal-Sturgess, C. E.

10.1101/2021.02.24.432748 — evolutionary biology — Posted on 2021-03-02

4576 Climate risk to European fisheries and coastal communities

Payne, M. R.; Kudahl, M.; Engelhard, G. H.; Peck, M. A.; Pinnegar, J. K.

10.1101/2020.08.03.234401 — ecology — Posted on 2021-03-02

4577 Coordinated Changes in Gene Expression Kinetics Underlie both Mouse and Human Erythroid Maturation

Barile, M.; Imaz-Rosshandler, I.; Inzani, I.; Ghazanfar, S.; Nichols, J.; Marioni, J. C.; Guibentif, C.; Gottgens, B.

10.1101/2020.12.21.423773 — developmental biology — Posted on 2021-03-02

4578 The SWI/SNF chromatin remodeling assemblies BAF and PBAF differentially regulate cell cycle exit and cellular invasion in vivo

Smith, J. J.; Xiao, Y.; Parsan, N.; Martinez, M. A. Q.; Moore, F. E. Q.; Palmisano, N. J.; Kohrman, A. Q.; Delos Reyes, M. C.; Adikes, R. C.; Medwig-Kinney, T. N.; Liu, S.; Bracht, S. A.; Zhang, W.; Wen, K.; Kratsios, P.; Matus, D. Q.

10.1101/2021.03.01.433447 — developmental biology — Posted on 2021-03-02

4579 ZFP207 controls pluripotency by multiple post-transcriptional mechanisms

Malla, S.; Prasad Bhattarai, D.; Melguizo-Sanchis, D.; Atanasoai, I.; Groza, P.; Roman, A. C.; Zhu, D.; Lee, D.-F.; Kutter, C.; Aguilo, F.

10.1101/2021.03.02.433507 — cell biology — Posted on 2021-03-02

4580 Microbial composition, diversity, and activity varies across different types of basal ice

Doyle, S. M.; Christner, B. C.

10.1101/2021.03.02.433610 — microbiology — Posted on 2021-03-02

4581 In vitro evaluation of the activity of terpenes and cannabidiol against Human Coronavirus E229

Chatow, L.; Nudel, A.; Nesher, I.; Hayo Hemo, D.; Rozenberg, P.; Voropaev, H.; Winkler, I.; Levy, R.; Kerem, Z.; Yaniv, Z.; Eyal, N.

10.1101/2021.03.01.433501 — microbiology — Posted on 2021-03-02

4582 A Self-Replicating Radiation-Shield for Human Deep-Space Exploration: Radiotrophic Fungi can Attenuate Ionizing Radiation aboard the International Space Station

Shunk, G. K.; Gomez, X. R.; Kern, C.; Averesch, N. J. H.

10.1101/2020.07.16.205534 — microbiology — Posted on 2021-03-02

4583 Disruption of the Pseudomonas aeruginosa Tat system perturbs PQS-dependent quorum sensing and biofilm maturation through loss of the Rieske cytochrome bc1 sub-unit

Soh, E. Y.-C.; Smith, F.; Gimenez, M.; Yang, L.; Vejborg, R.; Fletcher, M.; Halliday, N.; Bleves, S.; Heeb, S.; Camara, M.; Givskov, M.; Hardie, K.; Tolker-Nielsen, T.; Ize, B.; Williams, P.

10.1101/2021.03.01.433341 — microbiology — Posted on 2021-03-02

4584 The phytonutrient cinnamaldehyde limits intestinal inflammation and enteric parasite infection

Zhu, L.; Andersen-Civil, A.; Myhill, L.; Thamsborg, S. M.; Kot, W.; Krych, L.; Nielsen, D. S.; Blanchard, A.; Williams, A. R.

10.1101/2021.03.02.433624 — immunology — Posted on 2021-03-02

4585 Safety and Immunogenicity Evaluation of Inactivated whole-virus-SARS-COV-2 In Mice As Emerging Vaccine Development In Egypt

Ali, A. A.; Saad, M. A.; Ryan, I.; Amin, M.; Shindy, M. I.; Hassan, W. A.; Samir, M.; Khattab, A. A.; Abdelgayed, S. S.; Seadawy, M. G.; Fahmy, F. M.; Amer, K.

10.1101/2021.03.01.433130 — immunology — Posted on 2021-03-02

4586 Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation

Nguyen, G. T.; Xu, S.; Bunnell, S. C.; Mansour, M. K.; Sykes, D. B.; Mecsas, J.

10.1101/2021.03.02.433609 — immunology — Posted on 2021-03-02

4587 Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing

HU, C.; CHU, C.; LIU, L.; WANG, C.; jin, s.; yang, r.; rung, s.; li, j.; QU, Y.; MAN, Y.

10.1101/2020.08.10.243659 — immunology — Posted on 2021-03-02

4588 No balance between glutamate+glutamine and GABA+ in visual and motor cortices of the human brain

Rideaux, R.

10.1101/2021.03.02.433628 — neuroscience — Posted on 2021-03-02

4589 BonZeb: Open-source, modular software tools for high-resolution zebrafish tracking and analysis

Guilbeault, N. C.; Guerguiev, J.; Martin, M.; Tate, I.; Thiele, T. R.

10.1101/2021.03.02.433632 — neuroscience — Posted on 2021-03-02

4590 Rhythmic neuronal activities of the rat nucleus of the solitary tract are impaired by short-term high fat diet - implications for daily control of satiety by the brainstem

Chrobok, L.; Klich, J. D.; Sanetra, A. M.; Jeczmien-Lazur, J. S.; Pradel, K.; Palus-Chramiec, K.; Kepczynski, M.; Piggins, H. D.; Lewandowski, M. H.

10.1101/2021.03.02.433567 — neuroscience — Posted on 2021-03-02

4591 Slow rTMS to the left DLPFC enhances verbal memory formation

van der Plas, M.; Braun, V.; Stauch, B. J.; Hanslmayr, S.

10.1101/2021.03.02.433519 — neuroscience — Posted on 2021-03-02

4592 Age-dependent contribution of domain-general networks to semantic cognition

Martin, S.; Saur, D.; Hartwigsen, G.

10.1101/2020.11.06.371153 — neuroscience — Posted on 2021-03-02

4593 Frequency selectivity of persistent cortical oscillatory responses to auditory rhythmic stimulation

Pesnot Lerousseau, J.; Trebuchon, A.; Morillon, B.; Schon, D.

10.1101/834226 — neuroscience — Posted on 2021-03-02

4594 A study of the neuronal injury biomarkers pNF-H and UCHL1 in serum, CSF and urine in a cohort of thoracic endovascular aortic repair (TEVAR) patients.

Beck, A.; Marin, V.; Deng, J.; Madorsky, I.; Ren, B.; Guo, Y.; Neal, D.; Shaw, G.

10.1101/2021.03.02.433405 — neuroscience — Posted on 2021-03-02

4595 Effector-independent brain network for auditory-motor integration: fMRI evidence from singing and cello playing

Segado, M.; Zatorre, R. J.; Penhune, V. B.

10.1101/2020.12.24.423508 — neuroscience — Posted on 2021-03-02

4596 REPP: A robust cross-platform solution for online sensorimotor synchronization experiments

Anglada-Tort, M.; Harrison, P. M. C.; Jacoby, N.

10.1101/2021.01.15.426897 — neuroscience — Posted on 2021-03-02

4597 Medium-throughput zebrafish optogenetic platform identifies deficits in subsequent neural activity following brief early exposure to cannabidiol and Δ-9-tetrahydrocannabinol

Kanyo, R.; Amin, M. R.; Locskai, L. F.; Bouvier, D. D.; Olthuis, A. M.; Allison, W. T.; Ali, D. W.

10.1101/2021.01.04.425279 — pharmacology and toxicology — Posted on 2021-03-02

4598 CD19-targeting CAR T cells potently redirected to kill solid tumor cells

Ambrose, C.; Su, L.; Wu, L.; Dufort, F. J.; Stanford, T.; Birt, A.; Hackel, B. J.; Hombach, A. A.; Abken, H.; Lobb, R. R.; Rennert, P. D.

10.1101/2020.03.25.007658 — cancer biology — Posted on 2021-03-02

4599 Fragment-based computational design of antibodies targeting structured epitopes

Aguilar Rangel, M.; Bedwell, A.; Costanzi, E.; Ricagno, S.; Frydman, J.; Vendruscolo, M.; Sormanni, P.

10.1101/2021.03.02.433360 — bioinformatics — Posted on 2021-03-02

4600 DeepMOCCA: A pan-cancer prognostic model identifies personalized prognostic markers through graph attention and multi-omics data integration

Althubaiti, S.; Kulmanov, M.; Liu, Y.; Gkoutos, G.; Schofield, P.; Hoehndorf, R.

10.1101/2021.03.02.433454 — bioinformatics — Posted on 2021-03-02

4601 Genomic Copy Number Signatures Based Classifiers for Subtype Identification in Cancer

Gao, B.; Baudis, M.

10.1101/2020.12.18.423278 — bioinformatics — Posted on 2021-03-02

4602 Death comes for us all: an interplay of habitat selection, movement, and social behavior relate to cause specific mortality among grey wolves

Turner, J. W.; Prokopenko, C. M.; Kingdon, K. A.; Dupont, D.; Zabihi-Seissan, S.; Vander Wal, E.

10.1101/2021.03.02.433605 — animal behavior and cognition — Posted on 2021-03-02

4603 Clonal evolution in serially passaged Cryptococcus neoformans x deneoformans hybrids reveals a heterogenous landscape of mitotic recombination

Michelotti, L. A.; Sun, S.; Heitman, J.; James, T. Y.

10.1101/2021.03.02.433606 — genetics — Posted on 2021-03-02

4604 Variation in adaptation across geographic ranges is consistent with strong selection in marginal climates and legacies of range expansion

Bontrager, M.; Usui, T.; Lee-Yaw, J. A.; Anstett, D. N.; Branch, H. A.; Hargreaves, A. L.; Muir, C. D.; Angert, A. L.

10.1101/2020.08.22.262915 — evolutionary biology — Posted on 2021-03-02

4605 Body mass, temperature, and depth shape the maximum intrinsic rate of population increase in sharks and rays

Pardo, S. A.; Dulvy, N. K.

10.1101/2021.03.02.433372 — ecology — Posted on 2021-03-02

4606 Desmosomal dualism: the core is stable while plakophilin is dynamic.

Fulle, J. B.; Huppert, H.; Liebl, D.; Liu, J.; Alves de Almeida, R.; Yanes, B.; Wright, G. D.; Lane, E. B.; Garrod, D. R.; Ballestrem, C.

10.1101/2021.03.02.433631 — cell biology — Posted on 2021-03-02

4607 Compositional analysis of ALS-linked stress granule-like structures reveals factors and cellular pathways dysregulated by mutant FUS under stress

An, H.; Litscher, G.; Wei, W.; Watanabe, N.; Hashimoto, T.; Iwatsubo, T.; Buchman, V. L.; Shelkovnikova, T. A.

10.1101/2021.03.02.433611 — cell biology — Posted on 2021-03-02

4608 A heterohexameric protein consisting of six linked single-domain antibodies is highly protective for BoNT/A, BoNT/B and BoNT/E exposures

Shoemaker, C. B.; Mukherjee, J.; Debatis, M.; Tremblay, J. M.; Awata, J.; Foss, A.

10.1101/2021.03.02.433625 — molecular biology — Posted on 2021-03-02

4609 Increased Resistance of SARS-CoV-2 Variant P.1 to Antibody Neutralization

Wang, P.; Wang, M.; Yu, J.; Cerutti, G.; Nair, M. S.; Huang, Y.; Kwong, P. D.; Shapiro, L.; Ho, D. D.

10.1101/2021.03.01.433466 — microbiology — Posted on 2021-03-02

4610 Vaccination with SARS-CoV-2 Spike Protein and AS03 Adjuvant Induces Rapid Anamnestic Antibodies in the Lung and Protects Against Virus Challenge in Nonhuman Primates

Francica, J. R.; Flynn, B. J.; Foulds, K. E.; Noe, A. T.; Werner, A. P.; Morre, I. N.; Gagne, M.; Johnston, T. S.; Tucker, C.; Davis, R. L.; Flach, B.; O'Connell, S.; Andrew, S. F.; Lamb, E.; Flebbe, D. R.; Nurmukhambetova, S. T.; Donaldson, M. M.; Todd, J.-P. M.; Zhu, A. L.; Atyeo, C.; Fischinger, S.; Gorman, M. J.; Shin, S.; Edara, V. V.; Floyd, K.; Lai, L.; Tylor, A.; McCarthy, E.; Lecouturier, V.; Ruiz, S.; Berry, C.; Tibbitts, T.; Andersen, H.; Cook, A.; Dodson, A.; Pessaint, L.; Ry, A. V.; Koutsoukos, M.; Gutzeit, C.; Teng, I.-T.; Zhou, T.; Li, D.; Haynes, B. F.; Kwong, P. D.; McDermott,

10.1101/2021.03.02.433390 — immunology — Posted on 2021-03-02

4611 High resolution profiling of MHC-II peptide presentation capacity, by Mammalian Epitope Display, reveals SARS-CoV-2 targets for CD4 T cells and mechanisms of immune-escape

Obermair, F. J.; Renoux, F.; Heer, S.; Lee, C.; Cereghetti, N.; Maestri, G.; Haldner, Y.; Wuigk, R.; Iosefson, O.; Patel, P.; Triebel, K.; Kopf, M.; Swain, J.; Kisielow, J.

10.1101/2021.03.02.433522 — immunology — Posted on 2021-03-02

4612 Factors influencing maternal microchimerism throughout infancy and its impact on infant T cell immunity

Balle, C.; Kiravu, A.; Hoffmann, A.; Happel, A.-U.; Kanaan, S. B.; Nelson, J. L.; Gray, C.; Jaspan, H. B.; Harrington, W. E.

10.1101/2021.03.02.432825 — immunology — Posted on 2021-03-02

4613 Intrinsic cardiac adrenergic cell contributes to septic cardiomyopathy

Yang, D.; Dai, X.; Xing, Y.; Tang, X.; Yang, G.; Wang, P.; Harrison, A. G.; Li, H.; Lv, X.; Yu, X.; Wang, H.

10.1101/2021.03.02.433552 — immunology — Posted on 2021-03-02

4614 Protection against neonatal respiratory viral infection via maternal treatment during pregnancy with the benign immune training agent OM-85

Lauzon-Joset, J.-F.; Mincham, K. T.; Scott, N. M.; Khandan, Y.; Stumbles, P. A.; Holt, P. G.; Strickland, D. H.

10.1101/2021.03.02.433517 — immunology — Posted on 2021-03-02

4615 FAM57B is a modulator of ceramide synthesis that regulates sphingolipid homeostasis and synaptic composition in the developing brain

Tomasello, D. L.; Kim, J. L.; Khodour, Y.; McCammon, J. M.; Mitalipova, M.; Jaenisch, R.; Futerman, A. H.; Sive, H.

10.1101/2021.03.02.433619 — neuroscience — Posted on 2021-03-02

4616 High-content screening of coronavirus genes for innate immune suppression revealsenhanced potency of SARS-CoV-2 proteins

Olson, E. J.; Brown, D. M.; Chang, T. Z.; Ding, L.; Ng, T. L.; Weiss, H. S.; Koch, P.; Koide, Y.; Rollins, N.; Mach, P.; Meisinger, T.; Bricken, T.; Rollins, J.; Zhang, Y.; Molloy, C.; Zhang, Y.; Queenan, B. N.; Mitchison, T.; Marks, D.; Way, J. C.; Glass, J. I.; Silver, P. A.

10.1101/2021.03.02.433434 — systems biology — Posted on 2021-03-02

4617 Dynamic neurogenomic responses to social interactions and dominance outcomes in female paper wasps

Uy, F. M.; Jernigan, C. M.; Zaba, N. C.; Mehrotra, E.; Miller, S. E.; Sheehan, M. J.

10.1101/2021.03.01.433260 — genomics — Posted on 2021-03-02

4618 Plant hydraulics coordinated with photosynthetic traits and climate

Xu, H.; Wang, H.; Prentice, I. C.; Harrison, S. P.; Wright, I.

10.1101/2021.03.02.433324 — ecology — Posted on 2021-03-02

4619 Metabolic dysfunction induced by high-fat diet modulates hematopoietic stem and myeloid progenitor cells in brown adipose tissue of mice

Mincham, K. T.; Panchal, K.; Hart, P. H.; Lucas, R. M.; Feelisch, M.; Weller, R. B.; Matthews, V. B.; Strickland, D. H.; Gorman, S.

10.1101/2021.03.02.433510 — cell biology — Posted on 2021-03-02

4620 Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain

Khan, S. S.; Sobu, Y.; Dhekne, H. S.; Tonelli, F.; Berndsen, K.; Alessi, D. R.; Pfeffer, S. R.

10.1101/2021.03.02.433576 — cell biology — Posted on 2021-03-02

4621 Recalled parental bonding interacts with oxytocin receptor gene polymorphism in modulating anxiety and avoidance in adult relationships

Cataldo, I.; Bonassi, A.; Lepri, B.; Foo, J. N.; Setoh, P.; Esposito, G.

10.1101/2020.07.01.181644 — neuroscience — Posted on 2021-03-02

4622 Hypothalamic Overexpression of Neurosecretory Protein GL Leads to Obesity in Mice

Narimatsu, Y.; Fukumura, K.; Shikano, K.; Iwakoshi-Ukena, E.; Furumitsu, M.; Bentley, G. E.; Kriegsfeld, L. J.; Ukena, K.

10.1101/2021.03.01.433475 — neuroscience — Posted on 2021-03-02

4623 The impact of real-time fMRI denoising on online evaluation of brain activity and functional connectivity

Misaki, M.; Bodurka, J.

10.1101/2021.03.02.433573 — neuroscience — Posted on 2021-03-02

4624 Leveraging joint mechanics simplifies the neural control of movement

Ludvig, D.; Whitmore, M. W.; Perreault, E. J.

10.1101/2021.03.02.433588 — neuroscience — Posted on 2021-03-02

4625 Arabidopsis annexin 5 controls plasma membrane properties in mature pollen grains

Lichocka, M.; Krzymowska, M.; Gorecka, M.; Hennig, J.

10.1101/2021.03.02.433530 — plant biology — Posted on 2021-03-02

4626 Optimal BR signalling is required for adequate cell wall orientation in the Arabidopsis root meristem

Li, Z.; Sela, A.; Fridman, Y.; Hofte, H.; Savaldi-Goldstein, S.; Wolf, S.

10.1101/2021.03.02.433562 — plant biology — Posted on 2021-03-02

4627 A New Straightforward Method for Automated Segmentation of Trabecular Bone from Cortical Bone in Diverse and Challenging Morphologies

Herbst, E. C.; Felder, A. A.; Evans, L. A. E.; Ajami, S.; Javaheri, B.; Pitsillides, A. A.

10.1101/2021.03.02.433409 — physiology — Posted on 2021-03-02

4628 State-Transition Analysis of Time-Sequential microRNA Expression Predicts Development of Acute Myeloid Leukemia

Frankhouser, D. E.; O'Meally, D.; Branciamore, S.; Uechi, L.; Qin, H.; Wu, X.; Carlesso, N.; Marcucci, G.; Kuo, Y.-H.; Rockne, R. C.

10.1101/2021.03.02.433582 — cancer biology — Posted on 2021-03-02

4629 Meeting experiments at the diffraction barrier: an in-silico widefield fluorescence microscopy

Mahajan, S.; Tang, T.

10.1101/2021.03.02.433395 — biophysics — Posted on 2021-03-02

4630 A modular, dynamic, DNA-based platform for regulating cargo distribution and transport between lipid domains

Rubio-Sánchez, R.; Eizagirre Barker, S.; Walczak, M.; Cicuta, P.; Di Michele, L.

10.1101/2021.03.02.433457 — biophysics — Posted on 2021-03-02

4631 HiCzin: Normalizing metagenomic Hi-C data and detecting spurious contacts using zero-inflated negative binomial regression

Du, Y.; Laperriere, S. M.; Fuhrman, J.; Sun, F.

10.1101/2021.03.01.433489 — bioinformatics — Posted on 2021-03-02

4632 Panakeia - A universal tool for bacterial pangenome analysis

Beier, S.; Thomson, N. R.

10.1101/2021.03.02.433540 — bioinformatics — Posted on 2021-03-02

4633 Using Graph Convolutional Neural Networks to Learn a Representation for Glycans

Burkholz, R.; Quackenbush, J.; Bojar, D.

10.1101/2021.03.01.433491 — bioinformatics — Posted on 2021-03-02

4634 Drug-driven reclassification of multiple tumour subtypes reveals intrinsic molecular concordance of therapy across histologically disparate cancers

Xu, Y.; Zheng, J.; Cai, Z.; Li, W.; Kohler, J.; Dai, Y.; Cheng, X.; Wu, T.; Zhang, F.; Wang, H.

10.1101/2021.03.02.433516 — bioinformatics — Posted on 2021-03-02

4635 Uncovered genetic diversity in Hemidactylus mabouia (Reptilia: Gekkonidae) from Madeira Island reveals uncertain sources of introduction

Rato, C.; Martins, B.; Rocha, R.; Silva-Rocha, I.

10.1101/2021.03.02.433159 — evolutionary biology — Posted on 2021-03-02

4636 Modelling the impact of decidual senescence on embryo implantation in human endometrial assembloids

Rawlings, T. M.; Makwana, K.; Taylor, D. M.; Mole, M. A.; Fishwick, K. J.; Tryfonos, M.; Odendaal, J.; Hawkes, A.; Zernicka-Goetz, M.; Hartshorne, G.; Brosens, J.; Lucas, E. S.

10.1101/2021.03.02.433560 — developmental biology — Posted on 2021-03-02

4637 Targeted Next Generation Sequencing of environmental DNA improves detection and quantification of invasive European green crab (Carcinus maenas)

Westfall, K. M.; Therriault, T. W.; Abbott, C. L.

10.1101/2021.03.01.433397 — molecular biology — Posted on 2021-03-02

4638 Comparative analysis of RNA enrichment methods for preparation of Cryptococcus neoformans RNA sequencing libraries

Telzrow, C. L.; Zwack, P. J.; Righi, S. E.; Dietrich, F. S.; Chan, C.; Owzar, K.; Alspaugh, J. A.; Granek, J. A.

10.1101/2021.03.01.433483 — microbiology — Posted on 2021-03-02

4639 High-quality complete genome resource of plant pathogenic bacterium Dickeya solani strain IPO 2019 isolated from Hyacinthus orientalis

Czajkowski, R.; Rabalski, L.; Bartnik, P.; Jafra, S.

10.1101/2021.03.02.433526 — microbiology — Posted on 2021-03-02

4640 Antigen and Checkpoint Receptor Recalibration of T Cell Receptor Signal Strength

Elliot, T. A. E.; Jennings, E. K.; Lecky, D. A. J.; Thawait, N.; Flores-Langarica, A.; Wraith, D. C.; Bending, D.

10.1101/2021.03.02.431957 — immunology — Posted on 2021-03-02

4641 Genome-wide screens identify calcium signaling as a key regulator of IgE+ plasma celldifferentiation and survival

Newman, R.; Tolar, P.

10.1101/2021.03.02.433398 — immunology — Posted on 2021-03-02

4642 Cooperative Stabilization of Close-Contact Zones Leads to Sensitivity and Selectivity in T-Cell Recognition

Rozycki, B.; Weikl, T. R.

10.1101/2021.03.02.433515 — immunology — Posted on 2021-03-02

4643 Transient beta activity and connectivity during sustained motor behaviour

Echeverria-Altuna, I.; Quinn, A. J.; Zokaei, N.; Woolrich, M. W.; Nobre, A. C.; van Ede, F.

10.1101/2021.03.02.433514 — neuroscience — Posted on 2021-03-02

4644 Multitaper estimates of phase-amplitude coupling

Lepage, K. Q.; Fleming, C. N.; Witcher, M.; Vijayan, S.

10.1101/2021.03.02.433586 — neuroscience — Posted on 2021-03-02

4645 Preparation of large-scale digitization samples for automated electron microscopy of tissue and cell ultrastructure

Dittmayer, C.; Goebel, H.-H.; Heppner, F. L.; Stenzel, W.; Bachmann, S.

10.1101/2021.03.02.433512 — neuroscience — Posted on 2021-03-02

4646 On the generalizability of diffusion MRI signal representations across acquisition parameters, sequences and tissue types: chronicles of the MEMENTO challenge.

De Luca, A.; Ianus, A.; Leemans, A.; Palombo, M.; Shemesh, N.; Zhang, H.; Alexander, D. C.; Nilsson, M.; Froeling, M.; Biessels, G.-J.; Zucchelli, M.; Frigo, M.; Albay, E.; Sedlar, S.; Alimi, A.; Deslauriers-Gauthier, S.; Deriche, R.; Fick, R.; Afzali, M.; Pieciak, T.; Bogusz, F.; Aja-Fernandez, S.; Ozarslan, E.; Jones, D. K.; Chan, H.; Jin, M.; Zhang, Z.; Wang, F.; Nath, V.; Parvathaneni, P.; Morez, J.; Sijbers, J.; Jeurissen, B.; Fadnavis, S.; Endres, S.; Rokem, A.; Garyfallidis, E.; Sanchez, I.; Prchkovska, V.; Rodrigues, P.; Landman, B. A.; Schilling, K. G.

10.1101/2021.03.02.433228 — neuroscience — Posted on 2021-03-02

4647 Distinct forms of synaptic plasticity during ascending vs. descending control of medial olivocochlear efferent neurons

Romero, G. E.; Trussell, L. O.

10.1101/2021.03.02.433557 — neuroscience — Posted on 2021-03-02

4648 Predicting biological pathways of chemical compounds with a profile-inspired aproach

Lopez-Ibanez, J.; Pazos, F.; Chagoyen, M.

10.1101/2021.03.02.433511 — systems biology — Posted on 2021-03-02

4649 Geminiviral genomes encode additional proteins with specific subcellular localizations and virulence function

Gong, P.; Tan, H.; Zhao, S.; Li, H.; Liu, H.; Ma, Y.; Zhang, X.; Rong, J.; Fu, X.; Lozano-Duran, R.; Li, F.; Zhou, X.

10.1101/2021.03.01.433473 — plant biology — Posted on 2021-03-02

4650 The anti-immune dengue subgenomic flaviviral RNA is found in vesicles in mosquito saliva and associated with increased infectivity

Yeh, S.-C.; Tan, W.-L.; Chowdhury, A.; Kini, R.; Chuo, V.; Pompon, J.; Garcia-Blanco, M. A.

10.1101/2021.03.02.433543 — physiology — Posted on 2021-03-02

4651 Olanzapine leads to nonalcoholic fatty liver disease through the apolipoprotein A5 pathway

Li, R.; Zhu, W.; Huang, P.; Yang, Y.; Luo, F.; Dai, W.; Shen, L.; Pei, W.; Huang, X.

10.1101/2021.03.02.433415 — pathology — Posted on 2021-03-02

4652 Slow, heterogeneous NFκB single molecule conformational dynamics and implications for function

Chen, W.; Liu, W.; Wolynes, P. G.; Komives, E. A.

10.1101/2021.03.02.433616 — biophysics — Posted on 2021-03-02

4653 Multi-dimensional and spatiotemporal correlative imaging at the plasma membrane of live cells to determine the continuum nano-to-micro scale lipid adaptation and collective motion

Bernabe-Rubio, M.; Bosch-Fortea, M.; Alonso, M. A.; Bernardino de la Serna, J.

10.1101/2021.03.02.433589 — biophysics — Posted on 2021-03-02

4654 Chromatin Network Retards Droplet Coalescence

Qi, Y.; Zhang, B.

10.1101/2021.03.02.433564 — biophysics — Posted on 2021-03-02

4655 The glycocalyx affects force loading-dependent mechanotransductive topography sensing at the nanoscale

Chighizola, M.; Dini, T.; Marcotti, S.; D'Urso, M.; Piazzoni, C.; Borghi, F.; Previdi, A.; Ceriani, L.; Folliero, C.; Stramer, B.; Lenardi, C.; Milani, P.; Podestà, A.; Schulte, C.

10.1101/2021.03.02.433591 — biophysics — Posted on 2021-03-02

4656 Perturbation of ACE2 structural ensembles by SARS-CoV-2 spike protein binding

Uyar, A.; Dickson, A.

10.1101/2021.03.02.433608 — biophysics — Posted on 2021-03-02

4657 Intracellular Oxidative Stress Levels are Significantly Associated with the Green Autofluorescence Intensity of Buthionine Sulfoximine-Treated B16-F10 Cells

Tang, W.; Ying, W.

10.1101/2021.03.02.433583 — biophysics — Posted on 2021-03-02

4658 Transcription elongation through lac repressor-mediated DNA loops

Xu, W.; Yan, Y.; Artsimovitch, I.; Sunday, N.; Dunlap, D.; Finzi, L.

10.1101/2021.03.02.433568 — biophysics — Posted on 2021-03-02

4659 Towards a global investigation of transcriptomic signatures through co-expression networks and pathway knowledge for the identification of disease mechanisms

Figueiredo, R. Q.; Raschka, T.; Kodamullil, A. T.; Apitius, M. H.; Mubeen, S.; Domingo-Fernandez, D.

10.1101/2021.03.02.433520 — bioinformatics — Posted on 2021-03-02

4660 Adaptation to DNA damage as a bet-hedging mechanism in a fluctuating environment

Roux, P.; Salort, D.; Xu, Z.

10.1101/2021.03.02.433602 — bioinformatics — Posted on 2021-03-02

4661 A pan-ontology view of machine-derived knowledge representations and feedback mechanisms for curation

Konopka, T.; Smedley, D.

10.1101/2021.03.02.433532 — bioinformatics — Posted on 2021-03-02

4662 Human stem cell-based retina-on-chip as new translational model for validation of AAV retinal gene therapy vectors

Achberger, K.; Cipriano, M.; Duechs, M.; Schoen, C.; Michelfelder, S.; Stierstorfer, B.; Lamla, T.; Kauschke, S.; Chuchuy, J.; Roosz, J.; Mesch, L.; Cora, V.; Pars, S.; Pashkovskaia, N.; Corti, S.; Kleger, A.; Kreuz, S.; Maier, U.; Liebau, S.; Loskill, P.

10.1101/2021.03.02.433550 — bioengineering — Posted on 2021-03-02

4663 Injury-Free In Vivo Delivery and Engraftment into the Cornea Endothelium Using Extracellular Matrix Shrink-Wrapped Cells

Palchesko, R. N.; Du, Y.; Geary, M.; Carrasquilla, S.; Shiwarski, D. J.; Khandaker, I.; Feunderburgh, J. L.; Feinberg, A. W.

10.1101/2021.03.01.433476 — bioengineering — Posted on 2021-03-02

4664 AMPylation is a specific lysosomal protein posttranslational modification in neuronal maturation.

Becker, T.; Cappel, C.; Di Matteo, F.; Sonsalla, G.; Kaminska, E.; Spada, F.; Cappello, S.; Damme, M.; Kielkowski, P.

10.1101/2021.03.02.433531 — biochemistry — Posted on 2021-03-02

4665 Structural basis for the hyperthermostability of an archaeal glutaminase induced by post-translational succinimide formation

Balaram, H.; Dongre, A. V.; Das, S.; Bellur, A.; Kumar, S.; Chandrashekarmath, A.; Karmakar, T.; Balaram, P.; Balasubramanian, S.

10.1101/2021.03.02.433506 — biochemistry — Posted on 2021-03-02

4666 Deriving accurate molecular indicators of protein synthesis through Raman-based sparse classification

Pavillon, N.; Smith, N. I.

10.1101/2021.03.02.433529 — biochemistry — Posted on 2021-03-02

4667 Pericentromeric heterochromatin impacts genome compartmentalization and sex chromosome evolution in a fish

Xue, L.; Gao, Y.; Wu, M.; Fan, H.; Huang, Y.; Huang, Z.; Li, D.; Xu, L.

10.1101/2021.03.01.433482 — genomics — Posted on 2021-03-02

4668 Multiple targets of balancing selection in Leishmania donovani complex parasites

Grace, C. A.; Forrester, S.; Silva, V. C.; Aare, A.; Kilford, H.; Chew, Y. P.; James, S.; Costa, D. L.; Mottram, J. C.; Costa, C. C. H. N.; Jeffares, D. C.

10.1101/2021.03.02.433528 — evolutionary biology — Posted on 2021-03-02

4669 " Idol with feet of clay ": reliable predictions of forest ecosystem functioning require flawless climate forcings.

Jourdan, M.; Francois, C.; Delpierre, N.; Martin St-Paul, N.; Dufrene, E.

10.1101/2021.03.02.433613 — ecology — Posted on 2021-03-02

4670 Limited selection towards lighter seeds in 1 Danish grasslands over an eight-year period

Damgaard, C.

10.1101/2021.03.02.433513 — ecology — Posted on 2021-03-02

4671 Implications of the evolution of agriculture and resource foraging for the maintenance of species diversity and community structure

Picot, A.; Monnin, T.; Loeuille, N.

10.1101/2021.03.02.433551 — ecology — Posted on 2021-03-02

4672 The Hob proteins are novel and conserved lipid binding proteins at ER-PM contact site

Neuman, S. D.; Jorgensen, J. R.; Cavanagh, A. T.; Smyth, J. T.; Selegue, J. E.; Emr, S. D.; Bashirullah, A.

10.1101/2021.03.02.433623 — cell biology — Posted on 2021-03-02

4673 The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation

Chavkin, N. W.; Sano, S.; Wang, Y.; Oshima, K.; Horitani, K.; Sano, M.; MacLauchlan, S.; Nelson, A.; Setia, K.; Vippa, T.; Watanabe, Y.; Saucerman, J. J.; Hirschi, K. K.; Gokce, N.; Walsh, K.

10.1101/2021.03.02.433549 — cell biology — Posted on 2021-03-02

4674 A CTDNEP1-lipin 1-mTOR regulatory network restricts ER membrane biogenesis to enable chromosome motions necessary for mitotic fidelity

Merta, H.; Carrasquillo Rodriguez, J. W.; Anjur-Dietrich, M. I.; Granade, M. E.; Vitale, T.; Harris, T. E.; Needleman, D. J.; Bahmanyar, S.

10.1101/2021.03.02.433553 — cell biology — Posted on 2021-03-02

4675 Role of BRCA2 DNA-binding and C-terminal domain on its mobility and conformation in DNA repair

Paul, M. W.; Sidhu, A.; Liang, Y.; van Rossum-Fikkert, S. E.; Odijk, H.; Zelensky, A. N.; Kanaar, R.; Wyman, C.

10.1101/2021.03.02.433541 — molecular biology — Posted on 2021-03-02

4676 An ancient retroviral RNA element hidden in mammalian genomes and its involvement in co-opted retroviral gene regulation

Kitao, K.; Nakagawa, S.; Miyazawa, T.

10.1101/2021.03.02.433518 — molecular biology — Posted on 2021-03-02

4677 A simple, cost-effective and automation-friendly direct PCR approach for bacterial community analysis

Song, F.; Kuehl, J. V.; Chandran, A.; Arkin, A. P.

10.1101/2021.03.01.433496 — microbiology — Posted on 2021-03-02

4678 Feline leukemia virus (FeLV) endogenous and exogenous recombination events result in multiple FeLV-B subtypes during natural infection

Erbeck, K.; Gagne, R. B.; Kraberger, S.; Chiu, E.; Roelke-Parker, M.; Vandewoude, S.

10.1101/2021.03.01.433497 — microbiology — Posted on 2021-03-02

4679 Genomic characterization of four novel bacteriophages infecting the clinical pathogen Klebsiella pneumoniae

Estrada Bonilla, B.; Costa, A. R.; van Rossum, T.; Hagedoorn, S.; Walinga, H.; Xiao, M.; Song, W.; Haas, P.-J.; Nobrega, F. L.; Brouns, S. J.

10.1101/2021.03.02.433402 — microbiology — Posted on 2021-03-02

4680 Synthetic algal-bacteria consortia for space-efficient microalgal growth in a simple hydrogel system

Martin, N.; Bernat, T.; Dinasquet, J.; Stofko, A.; Damon, A.; Deheyn, D.; Azam, F.; Smith, J.; Davey, M. P.; Smith, A. G.; Vignolini, S.; Wangpraseurt, D.

10.1101/2021.03.01.433490 — microbiology — Posted on 2021-03-02

4681 Ammonia-oxidizing archaea possess a wide range of cellular ammonia affinities

Jung, M.-Y.; Sedlacek, C. J.; Kits, K. D.; Mueller, A. J.; Rhee, S.-K.; Hink, L.; Nicol, G. W.; Bayer, B.; Lehtovirta-Morley, L.; Wright, C. L.; de la Torre, J. R.; Herbold, C. W.; Pjevac, P.; Daims, H.; Wagner, M.

10.1101/2021.03.02.433310 — microbiology — Posted on 2021-03-02

4682 Memory CD8+ T cells mediate early pathogen-specific protection through localized delivery of chemokines and IFNγ to clusters of inflammatory monocytes

Boutet, M.; Benet, Z.; Guillen, E.; Koch, C.; SOUDJA, S. M.; Delahaye, F.; Fooksman, D.; Lauvau, G.

10.1101/2021.03.01.433468 — immunology — Posted on 2021-03-02

4683 The Orsay Virus as a model for population-wide viral infection dynamics

Pirenne, L.; Jakobs, M. A.; Jordan, D.; Franze, K.; Miska, E. A.

10.1101/2021.03.02.433572 — immunology — Posted on 2021-03-02

4684 Bacterial clearance caused by a single anti-M protein antibody simultaneously binding two separate epitopes

Bahnan, W.; Happonen, L.; Khakzad, H.; Kumra Ahnlide, V.; de Neergaard, T.; Wrighton, S.; Bratanis, E.; Tang, D.; Hellmark, T.; Bjorck, L.; Shannon, O.; Malmstrom, L.; Malmstrom, J.; Nordenfelt, P.

10.1101/2021.03.01.433494 — immunology — Posted on 2021-03-02

4685 Vaccine genetics of IGHV1-2 VRC01-class broadly neutralizing antibody precursor naive human B cells

Lee, J. H.; Toy, L.; Kos, J. T.; Safonova, Y.; Schief, W. R.; Watson, C. T.; Havenar-Daughton, C.; Crotty, S.

10.1101/2021.03.01.433480 — immunology — Posted on 2021-03-02

4686 Multi-scale hierarchical neural network models that bridge from single neurons in the primate primary visual cortex to object recognition behavior

Marques, T.; Schrimpf, M.; DiCarlo, J. J.

10.1101/2021.03.01.433495 — neuroscience — Posted on 2021-03-02

4687 Gallic Acid, a Methyl 3,4-Dihydroxybenzoate Derivative, Induces Neural Stem Cells to Differentiate and Proliferate

Jiang, J.; Liu, W.; Hai, J.; Luo, Y.; Chen, K.; Xin, Y.; Pan, J.; Hu, Y.; Gao, Q.; Xiao, F.; Luo, H.

10.1101/2021.03.01.433474 — neuroscience — Posted on 2021-03-02

4688 Top-down control of hippocampal signal-to-noise by prefrontal long-range inhibition

Malik, R.; Li, Y.; Schamiloglu, S.; Sohal, V. S.

10.1101/2021.03.01.433441 — neuroscience — Posted on 2021-03-02

4689 Closed-loop automated reaching apparatus (CLARA) for interrogating motor systems

Bowles, S.; Williamson, W. R.; Nettles, D.; Hickman, J.; Welle, C.

10.1101/2021.03.01.433419 — neuroscience — Posted on 2021-03-02

4690 The Disease-Associated Proteins Drosophila Nab2 and Ataxin-2 Interact with Shared RNAs and Coregulate Neuronal Morphology

Rounds, J. C.; Corgiat, E. B.; Ye, C.; Behnke, J. A.; Kelly, S. M.; Corbett, A. H.; Moberg, K. H.

10.1101/2021.03.01.433469 — neuroscience — Posted on 2021-03-02

4691 Satellite Cell Expression of RAGE is Important for Collateral Vessel Formation

Hansen, L. M.; Joseph, G.; Valdivia Cortes, A.; Taylor, W. R.

10.1101/2021.03.02.433612 — physiology — Posted on 2021-03-02

4692 FGFR inhibitor mediated dismissal of SWI/SNF complexes from YAP-dependent enhancers induces adaptive therapeutic resistance

Li, Y.; Qiu, X.; Wang, X.; Liu, H.; Geck, R.; Tewari, A. K.; Xiao, T.; Font-Tello, A.; Lim, K.; Kristen, J. L.; Morrow, M.; Vadhi, R.; Kao, P.-L.; Jaber, A.; Yerrum, S.; Xie, Y.; Chow, K.-H.; Cejas, P.; Nguyen, Q.-D.; Long, H. W.; Liu, X. S.; Toker, A.; Brown, M.

10.1101/2021.03.02.433446 — cancer biology — Posted on 2021-03-02

4693 Calling differential DNA methylation at cell-type resolution: avoiding misconceptions and promoting best practices

Jing, H.; Zheng, S.; Breeze, C.; Beck, S.; Teschendorff, A.

10.1101/2021.02.28.433245 — bioinformatics — Posted on 2021-03-02

4694 The perception of odor pleasantness is shared across cultures

Arshamian, A.; Gerkin, R. C.; Kruspe, N.; Wnuk, E.; Floyd, S.; O'Meara, C.; Rodriguez, G. G.; Lundstrom, J. N.; Mainland, J. D.; Majid, A.

10.1101/2021.03.01.433367 — animal behavior and cognition — Posted on 2021-03-02

4695 Copy number evolution in simple and complex tandem repeats across the C57BL/6 and C57BL/10 inbred mouse lines

Flynn, J. M.; Brown, E. J.; Clark, A. G.

10.1101/2021.03.01.433487 — evolutionary biology — Posted on 2021-03-02

4696 Ventral Stress Fibers Induce Plasma Membrane Deformation in Human Fibroblasts

Ghilardi, S. J.; Aronson, M. S.; Sgro, A. E.

10.1101/2021.03.01.433420 — cell biology — Posted on 2021-03-02

4697 Ongoing Global and Regional Adaptive Evolution of SARS-CoV-2

Rochman, N. D.; Wolf, Y. I.; Faure, G.; Mutz, P.; Zhang, F.; Koonin, E. V.

10.1101/2020.10.12.336644 — microbiology — Posted on 2021-03-02

4698 Nelfinavir markedly improves lung pathology in SARS-CoV-2-infected Syrian hamsters despite lack of an antiviral effect

10.1101/2021.02.01.429108 — microbiology — Posted on 2021-03-02

4699 A chicken IgY can efficiently inhibit the entry and replication of SARS-CoV-2 by targeting the ACE2 binding domain in vitro

Jingchen, W.; Yunfei, L.; Ying, R.; Xuanyu, Z.; Songqing, H.; Shuwen, W.; Qing, X.

10.1101/2021.02.16.430255 — immunology — Posted on 2021-03-02

4700 BIP4COVID19: Releasing impact measures for articles relevant to COVID-19

Vergoulis, T.; Kanellos, I.; Chatzopoulos, S.; Pla Karidi, D.; Dalamagas, T.

10.1101/2020.04.11.037093 — scientific communication and education — Posted on 2021-03-02

4701 Modeling of Deformable Cell Separation in a Microchannel with Sequenced Pillars

Hymel, S. J.; Fukioka, H.; Khismatullin, D. B.

10.1101/2021.03.01.433451 — bioengineering — Posted on 2021-03-02

4702 SARS-CoV-2 RBD-Tetanus toxoid conjugate vaccine induces a strong neutralizing immunity in preclinical studies

Valdes-Balbin, Y.; Santana-Mederos, D.; Quintero, L.; Fernandez, S.; Rodriguez, L.; Sanchez-Ramirez, B.; Perez, R.; Acosta, C.; Mendez, Y.; Ricardo, M. G.; Hernandez, T.; Bergado, G.; Pi, F.; Valdes, A.; Carmenate, T.; Ramirez, U.; Oliva, R.; Soubal, J.-P.; Garrido, R.; Cardoso, F.; Landys, M.; Farinas, M.; Gonzalez, H.; Enriquez, J.; Noa, E.; Suarez, A.; Fang, C.; Espinosa, L. A.; Ramos, Y.; Gonzalez, L. J.; Climent, Y.; Rojas, G.; Relova-Hernandez, E.; Cabrera-Infante, Y.; Losada, S. L.; Boggiano, T.; Ojito, E.; Leon-Monzon, K.; Chiodo, F.; Paquet, F.; Chen, G.; Rivera, D. G.; Garcia-Rivera,

10.1101/2021.02.08.430146 — immunology — Posted on 2021-03-02

4703 On the emergence of orientational order in folded proteins with implications for allostery

Chakraborty, D.; Mugnai, M. L.; Thirumalai, D.

10.1101/2021.03.01.433462 — biophysics — Posted on 2021-03-02

4704 Detecting Selection in Low-Coverage High-Throughput Sequencing Data using Principal Component Analysis

Meisner, J.; Albrechtsen, A.; Hanghøj, K.

10.1101/2021.03.01.432540 — bioinformatics — Posted on 2021-03-02

4705 Mako: a graph-based pattern growth approach to detect complex structural variants

Lin, J.; Yang, X.; Kosters, W.; Xu, T.; Jia, Y.; Wang, S.; Zhu, Q.; Ryan, M.; Guo, L.; Zhang, C.; The Human Genome Structural Variation Consortium, ; Lee, C.; Devine, S. E.; Eichler, E. E.; Ye, K.

10.1101/2021.03.01.433465 — bioinformatics — Posted on 2021-03-02

4706 Deciphering enhancer sequence using thermodynamics-based models and convolutional neural networks

Dibaeinia, P.; Sinha, S.

10.1101/2021.03.01.433444 — bioinformatics — Posted on 2021-03-02

4707 Brain expression quantitative trait locus and network analysis reveals downstream effects and putative drivers for brain-related diseases

de Klein, N.; Tsai, E. A.; Vochteloo, M.; Baird, D.; Huang, Y.; Chen, C.-Y.; van Dam, S.; Deelen, P.; Bakker, O.; El Garwany, O.; Ouyang, Z.; Marshall, E.; Zavodszky, M.; van Rheenen, W.; Veldink,, J. H.; Bakker, M. K.; Gaunt, T.; Runz, H.; Franke, L.; Westra, H.-J.

10.1101/2021.03.01.433439 — genomics — Posted on 2021-03-02

4708 Genetic Basis of Variation in Cocaine and Methamphetamine Consumption in Outbred Populations of Drosophila melanogaster

Baker, B.; Carbone, M. A.; Huang, W.; Anholt, R. R. H.; Mackay, T.

10.1101/2021.03.01.433403 — genetics — Posted on 2021-03-02

4709 Spontaneous neural oscillations influence behavior and sensory representations by suppressing neuronal excitability

Iemi, L.; Gwilliams, L.; Samaha, J.; Auksztulewicz, R.; Cycowicz, Y. M.; King, J.-R.; Nikulin, V. V.; Thesen, T.; Doyle, W.; Devinsky, O.; Schroeder, C. E.; Melloni, L.; Haegens, S.

10.1101/2021.03.01.433450 — neuroscience — Posted on 2021-03-02

4710 Distinct sub-cellular autophagy impairments occur independently of protein aggregation in induced neurons from patients with Huntington's disease

Pircs, K.; Drouin-Ouellet, J.; Gil, J.; Rezeli, M.; Grassi, D. A.; Garza, R.; Sharma, Y.; St-Amour, I.; Jonsson, M. E.; Johansson, P. A.; Harris, K.; Vuono, R.; Stoker, T.; Hersbach, B. A.; Sharma, K.; Lagerwall, J.; Lagerstrom, S.; Storm, P.; Horvath, V.; Hebert, S. S.; Marko-Varga, G.; Parmar, M.; Barker, R. A.; Jakobsson, J.

10.1101/2021.03.01.433433 — neuroscience — Posted on 2021-03-02

4711 Employing connectome-based models to predict working memory in multiple sclerosis

Manglani, H. R.; Fountain-Zaragoza, S.; Shankar, A.; Nicholas, J. A.; Prakash, R. S.

10.1101/2021.03.01.432930 — neuroscience — Posted on 2021-03-02

4712 Taxon-specific phytoplankton growth, nutrient utilization, and light limitation in the oligotrophic Gulf of Mexico

Yingling, N.; Kelly, T. B.; Shropshire, T. A.; Landry, M. R.; Selph, K. E.; Knapp, A. N.; Kranz, S. A.; Stukel, M. R.

10.1101/2021.03.01.433426 — plant biology — Posted on 2021-03-02

4713 Modeling gene x environment interactions in PTSD using glucocorticoid-induced transcriptomics in human neurons

Breen, M. S.; Rusielewicz, T.; Bader, H. N.; Seah, C.; Xu, C.; Hunter, C. J.; McCarthy, B.; Chattopadhyay, M.; Desarnaud, F.; Makotkine, I.; Flory, J. D.; Bierer, L. M.; Staniskyte, M.; NYSCF Global Array Team, ; Noggle, S. A.; Paull, D.; Brennand, K. J.; Yehuda, R.

10.1101/2021.03.01.433391 — pathology — Posted on 2021-03-02

4714 Interpretable Drug Target Predictions using Self-Expressiveness

Galeano, D. A.; Noto, S.; Jimenez, R.; Paccanaro, A.

10.1101/2021.03.01.433365 — bioinformatics — Posted on 2021-03-02

4715 ISTDECO: In Situ Transcriptomics Decoding by Deconvolution

Andersson, A.; Diego, F.; Hamprecht, F. A.; Wählby, C.

10.1101/2021.03.01.433040 — bioinformatics — Posted on 2021-03-02

4716 PuBliCiTy: Python Bioimage Computing Toolkit

Cicconet, M.

10.1101/2021.03.01.432926 — bioinformatics — Posted on 2021-03-02

4717 When is it Worth Working for Water? A Utility Maximization Theory

Reinagel, P.

10.1101/2021.03.01.433467 — animal behavior and cognition — Posted on 2021-03-02

4718 AB12PHYLO: an integrated pipeline for Maximum Likelihood phylogenetic inference from ABI trace data

Kaindl, L.; Small, C.; Stam, R.

10.1101/2021.03.01.433007 — evolutionary biology — Posted on 2021-03-02

4719 An evolutionary genomic approach reveals both conserved and species-specific genetic elements related to human disease in closely related Aspergillus fungi

Mead, M. E.; Steenwyk, J. L.; Silva, L. P.; de Castro, P. A.; Saeed, N.; Hillmann, F.; Goldman, G.; Rokas, A.

10.1101/2021.03.01.433394 — evolutionary biology — Posted on 2021-03-02

4720 The spatiotemporal organization of experience dictates hippocampal involvement in primary visual cortical plasticity

Finnie, P. S. B.; Komorowski, R. W.; Bear, M. F.

10.1101/2021.03.01.433430 — neuroscience — Posted on 2021-03-02

4721 Acid sphingomyelinase deactivation post-ischemia/ reperfusion promotes cerebral angiogenesis and brain remodeling via small extracellular vesicles

Yusuf, A. M.; Hagemann, N.; Zhang, X.; Zafar, M.; Hussner, T.; Bromkamp, C.; Martiny, C.; Tertel, T.; Boerger, V.; Schumacher, F.; Solari, F. A.; Hasenberg, M.; Kleinschnitz, C.; Doeppner, T. R.; Kleuser, B.; Sickmann, A.; Gunzer, M.; Giebel, B.; Kolesnick, R.; Gulbins, E.; Hermann, D. M.

10.1101/2021.03.01.433387 — neuroscience — Posted on 2021-03-02

4722 Acetylcholine boosts dendritic NMDA spikes in a CA3 pyramidal neuron model

Humphries, R.; MELLOR, J.; O'Donnell, C.

10.1101/2021.03.01.433406 — neuroscience — Posted on 2021-03-02

4723 Single Image-based Vignetting Correction for Improving the Consistency of Neural Activity Analysis in 2-Photon Functional Microscopy

Li, D.; Wang, G.; Werner, R.; Xie, H.; Guan, J.-S.; Hilgetag, C. C.

10.1101/2021.03.01.433412 — neuroscience — Posted on 2021-03-02

4724 Identification of the Rigid Core for Aged Liquid Droplets of the TDP-43 Low Complexity Domain

Fonda, B. D.; Jami, K. M.; Boulos, N. R.; Murray, D. T.

10.1101/2021.03.01.433427 — biophysics — Posted on 2021-03-02

4725 scMM: Mixture-of-experts multimodal deep generative model for single-cell multiomics data analysis.

Minoura, K.; Abe, K.; Nam, H.; Nishikawa, H.; Shimamura, T.

10.1101/2021.02.18.431907 — bioinformatics — Posted on 2021-03-02

4726 GMSECT: Genome-Wide Massive Sequence Exhaustive Com-parison Tool for structural and copy number variations

Singh, A.

10.1101/2021.03.01.433223 — bioinformatics — Posted on 2021-03-02

4727 Abnormal function in dentate nuclei precedes the onset of psychosis: a resting-state fMRI study in high-risk individuals

Arnold Anteraper, S.; Guell, X.; Collin, G.; Qi, Z.; Ren, J.; Nair, A.; Seidman, L. J.; Keshavan, M. S.; Zhang, T.; Tang, Y.; Li, H.; McCarley, R. W.; Niznikiewicz, M. A.; Shenton, M. E.; Stone, W. S.; Wang, J.; Whitfield-Gabrieli, S.

10.1101/2021.02.28.433240 — neuroscience — Posted on 2021-03-02

4728 Functional specialization within the inferior parietal lobes across cognitive domains

Numssen, O.; Bzdok, D.; Hartwigsen, G.

10.1101/2020.07.01.181602 — neuroscience — Posted on 2021-03-02

4729 Two opposite voltage-dependent currents control the unusual early development pattern of embryonic Renshaw cell electrical activity

Boeri, J.; Meunier, C.; Le Corronc, H.; Branchereau, P.; Timofeeva, Y.; Lejeune, F.-X.; Mouffle, C.; Arulkandarajah, H.; Mangin, J. M.; Legendre, P.; Czarnecki, A.

10.1101/2020.06.18.158931 — neuroscience — Posted on 2021-03-02

4730 A Comparison of Cell-Based and Cell-Cultured as Appropriate Common or Usual Names to Label Products Made from the Cells of Fish.

Hallman, W. K.; Hallman, W. K.

10.1101/2021.02.26.433119 — scientific communication and education — Posted on 2021-03-02

4731 Instructor-learner neural synchronization during elaborated feedback predicts learning transfer

Zhu, Y.; Leong, V.; Pan, Y.; Hou, Y.; Zhang, D.; Hu, Y.

10.1101/2021.02.28.433286 — scientific communication and education — Posted on 2021-03-02

4732 Small molecule SWELL1-LRRC8 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes

Gunasekar, S. K.; Xie, L.; Chheda, P. R.; Kang, C.; Kern, D. M.; My-Ta, C.; Kumar, A.; Maurer, J. M.; Gerber, E. E.; Grzesik, W. J.; Elliot-Hudson, M.; Zhang, Y.; Kulkarni, C. A.; Samuel, I.; Smith, J. K.; Nau, P.; Imai, Y.; Sheldon, R. D.; Taylor, E. B.; Lerner, D. J.; Norris, A. W.; Brohawn, S. G.; Kerns, R.; Sah, R.

10.1101/2021.02.28.432901 — physiology — Posted on 2021-03-02

4733 Social partner cooperativeness influences brain oxytocin transcription in Trinidadian guppies (Poecilia reticulata)

Dimitriadou, S.; Santos, E.; Croft, D. P.; van Aerle, R.; Ramnarine, I. W.; Filby, A. L.; Darden, S. K.

10.1101/2021.03.01.433346 — animal behavior and cognition — Posted on 2021-03-02

4734 Using empirical datasets to quantify uncertainty in inferences of landscape genetic resistance due to variation of individual-based genetic distance metrics

Beninde, J.; Frantz, A. C.

10.1101/2021.03.01.432986 — ecology — Posted on 2021-03-02

4735 Stability by gating plasticity in recurrent neural networks

Wilmes, K. A.; Clopath, C.

10.1101/2020.09.10.291120 — neuroscience — Posted on 2021-03-02

4736 Approximate Hidden Semi-Markov Models for Dynamic Connectivity Analysis in Resting-State fMRI

Fiecas, M. B.; Coffman, C.; Xu, M.; Hendrickson, T. J.; Mueller, B. A.; Klimes-Dougan, B.; Cullen, K. R.

10.1101/2021.03.01.433385 — neuroscience — Posted on 2021-03-02

4737 Parvalbumin Interneurons Inhibition onto BLA Projecting Neurons of the Anterior Insula Orchestrates Aversive Taste Memory Retrieval

Yiannakas, A.; Chandran, S. K.; Kayyal, H.; Gould, N.; Khamaisy, M.; Rosenblum, K.

10.1101/2021.03.01.433377 — neuroscience — Posted on 2021-03-02

4738 Effects of diffusion signal modeling and segmentation approaches on subthalamic nucleus parcellation

Milardi, D.; Basile, G. A.; Faskowitz, J.; Bertino, S.; Quartarone, A.; Anastasi, G.; Bramanti, A.; Cacciola, A.

10.1101/2021.02.28.433251 — neuroscience — Posted on 2021-03-02

4739 Metacognitive Computations for Information Search: Confidence in Control

Schulz, L.; Fleming, S. M.; Dayan, P.

10.1101/2021.03.01.433342 — neuroscience — Posted on 2021-03-02

4740 A breast cancer patient-derived xenograft and organoid platform for drug discovery and precision oncology

10.1101/2021.02.28.433268 — cancer biology — Posted on 2021-03-02

4741 Whole-cell segmentation of tissue images with human-level performance using large-scale data annotation and deep learning

10.1101/2021.03.01.431313 — bioinformatics — Posted on 2021-03-02

4742 The dynamic interactive network of long non-coding RNAs and chromatin accessibility facilitates erythroid differentiation

Ren, Y.; Zhu, J.; Han, Y.; Li, P.; Qu, H.; Zhang, Z.; Fang, X.

10.1101/2021.03.02.433076 — genomics — Posted on 2021-03-02

4743 Development of a yeast-based assay for bioavailable phosphorous

Shepherd, H. A. M.; Trentman, M. T.; Tank, J. L.; Praner, J.; Cervantes, A.; Chaudhary, P.; Gezelter, J.; Marrs, A. J.; Myers, K. A.; Welsh, J. R.; Wu, Y.-F. O.; Goodson, H. V.

10.1101/2021.02.28.433264 — ecology — Posted on 2021-03-02

4744 Embryonic requirements for Tcf12 in the development of the mouse coronal suture

Ting, M.-c.; Farmer, D.; Teng, C. S.; He, J.; Chai, Y.; Crump, G.; Maxson, R. E.

10.1101/2021.03.01.433456 — developmental biology — Posted on 2021-03-02

4745 Transcription factor action orchestrates the complex expression pattern of CRABS CLAW, a gynoecium developmental regulator in Arabidopsis

Gross, T.; Becker, A.

10.1101/2021.03.02.433508 — genetics — Posted on 2021-03-02

4746 ZFP207 controls pluripotency by multiple post-transcriptional mechanisms

Malla, S.; Prasad Bhattarai, D.; Melguizo-Sanchis, D.; Atanasoai, I.; Groza, P.; Roman, A. C.; Zhu, D.; Lee, D.-F.; Kutter, C.; Aguilo, F.

10.1101/2021.03.02.433507 — cell biology — Posted on 2021-03-02

4747 Long-term warming effects on the microbiome and nitrogen fixation of a common moss species in sub-Arctic tundra

Klarenberg, I. J.; Keuschnig, C.; Russi Colmenares, A. J.; Warshan, D.; Jungblut, A. D.; Jonsdottir, I. S.; Vilhelmsson, O.

10.1101/838581 — microbiology — Posted on 2021-03-02

4748 iGEM comes of age: trends in its research output.

Jainarayanan, A. K.; Galanis, A.; Nakara, A. M.; Kundlatsch, G. E.; Rubio Sanchez, R. M.

10.1101/2021.01.21.424716 — scientific communication and education — Posted on 2021-03-02

4749 Life history tradeoffs, division of labor and evolutionary transitions in individuality

Doulcier, G.; Hammerschmidt, K.; Bourrat, P.

10.1101/2020.10.23.352948 — evolutionary biology — Posted on 2021-03-02

4750 Recalled parental bonding interacts with oxytocin receptor gene polymorphism in modulating anxiety and avoidance in adult relationships

Cataldo, I.; Bonassi, A.; Lepri, B.; Foo, J. N.; Setoh, P.; Esposito, G.

10.1101/2020.07.01.181644 — neuroscience — Posted on 2021-03-02

4751 The SWI/SNF chromatin remodeling assemblies BAF and PBAF differentially regulate cell cycle exit and cellular invasion in vivo

Smith, J. J.; Xiao, Y.; Pars, N.; Martinez, M. A. Q.; Moore, F. E. Q.; Palmisano, N. J.; Kohrman, A. Q.; Delos Reyes, M. C.; Adikes, R. C.; Medwig-Kinney, T. N. N.; Liu, S.; Bracht, S.; Zhang, W.; Wen, K.; Kratsios, P.; Matus, D. Q.

10.1101/2021.03.01.433447 — developmental biology — Posted on 2021-03-02

4752 Imaging-based evaluation of pathogenicity by novel DNM2 variants associated with centronuclear myopathy

Fujise, K.; Okubo, M.; Abe, T.; Yamada, H.; Takei, K.; Nishino, I.; Takeda, T.; Noguchi, S.

10.1101/2021.03.01.433478 — cell biology — Posted on 2021-03-02

4753 Scaling of subcellular structures with cell length through decelerated growth

McInally, S. G.; Kondev, J.; Goode, B. L.

10.1101/2021.03.01.433461 — cell biology — Posted on 2021-03-02

4754 EHF is essential for epidermal and colonic epithelial homeostasis and suppresses Apc-initiated colonic tumorigenesis

Reehorst, C. M.; Nightingale, R.; Luk, I. Y.; Jenkins, L.; Koentgen, F.; Williams, D. S.; Darido, C.; Tan, F.; Anderton, H.; Chopin, M.; Schoffer, K.; Eissmann, M. F.; Buchert, M.; Mouradov, D.; Sieber, O. M.; Ernst, M.; Dhillon, A. S.; Mariadason, J. M.

10.1101/2021.03.01.433470 — cell biology — Posted on 2021-03-02

4755 Life history tradeoffs, division of labor and evolutionary transitions in individuality

Doulcier, G.; Hammerschmidt, K.; Bourrat, P.

10.1101/2020.10.23.352948 — evolutionary biology — Posted on 2021-03-02

4756 The Origin of Conductive-Pulse Sensing Inside a Nanopore and the Role of Electro-Hydrodynamics

Lastra, L.; Nguyen, M.; Farajpour, N.; Freedman, K. J.

10.1101/2020.09.25.310755 — biophysics — Posted on 2021-03-02

4757 Non-Parametric Analysis of Inter-Individual Relations Using an Attention-Based Neural Network

Morita, T.; Toyoda, A.; Aisu, S.; Kaneko, A.; Suda-Hashimoto, N.; Adachi, I.; Matsuda, I.; Koda, H.

10.1101/2020.03.25.994764 — animal behavior and cognition — Posted on 2021-03-02

4758 Ribosome profiling in Streptococcus pneumoniae reveals the role of methylation of 23S rRNA nucleotide G748 on ribosome stalling.

Shoji, T.; Takaya, A.; Kusuya, Y.; Takahashi, H.; Kawashima, H.

10.1101/2020.12.21.423859 — genomics — Posted on 2021-03-02

4759 A conserved HSF:miR169:NF-YA loop involved in tomato and Arabidopsis heat stress tolerance

Rao, S.; Jha, S.; Bansal, C.; Gupta, A.; Sorin, C.; Crespi, M.; Mathur, S.

10.1101/2021.01.01.425064 — genomics — Posted on 2021-03-02

4760 Exploring rare cellular activity in more than one million cells by a trans-scale-scope

Ichimura, T.; Kakizuka, T.; Horikawa, K.; Seiriki, K.; Kasai, A.; Hashimoto, H.; Fujita, K.; Watanabe, T. M.; Nagai, T.

10.1101/2020.06.29.179044 — cell biology — Posted on 2021-03-02

4761 PKD promotes activity-dependent AMPA receptorendocytosis in hippocampal neurons

Oueslati Morales, C. O.; Ignacz, A.; Bencsik, N.; Ratkai, A. E.; Lieb, W. S.; Eisler, S. A.; Szucs, A.; Schlett, K.; Hausser, A.

10.1101/2020.04.09.033514 — neuroscience — Posted on 2021-03-02

4762 Global Constraints within the Developmental Program of the Drosophila Wing

Alba, V.; Carthew, J. E.; Carthew, R. W.; Mani, M.

10.1101/2020.10.13.333740 — systems biology — Posted on 2021-03-01

4763 Effects of accumulated temperature on growth curve of Gynostemma pentaphyllum stem and leaf under the conditions of Simulated light under the forest

Dun, C.; Songsheng, W.; Shuanglong, L.; Daikun, W.

10.1101/2021.03.01.433332 — plant biology — Posted on 2021-03-01

4764 Plasma concentrations of progesterone in the preceding estrous cycle are associated with the intensity of estrus and fertility of Holstein cows

Madureira, A. M. L.; Burnett, T. A.; Borchardt, S.; Heuwieser, W.; Baes, C. F.; Vasconcelos, J. L. M.; Cerri, R. L. A.

10.1101/2021.03.01.433335 — physiology — Posted on 2021-03-01

4765 The impact of mutations on the structural and functional properties of SARS-CoV-2 proteins: A comprehensive bioinformatics analysis

Ikram, A.; Naz, A.; Awan, F.; Rauff, B.; Obaid, A.; Hakim, M. S.; Malik, A.

10.1101/2021.03.01.433340 — bioinformatics — Posted on 2021-03-01

4766 Social behaviour and vocalizations of the tent-roosting Honduran White Bat

Fernandez, A. A.; Schmidt, C.; Schmidt, S.; Rodriguez-Herrera, B.; Knörnschild, M.

10.1101/2021.03.01.433334 — animal behavior and cognition — Posted on 2021-03-01

4767 ASSOCIATION STUDY OF SIX CANDIDATE GENES WITH MAJOR DEPRESSIVE DISORDER IN THE NORTH-WESTERN POPULATION OF PAKISTAN

Akbar, N.; Alam, N.; Ali, S.; Ilyas, M.; Ahmed, H.; Mustafa, A.; Khurram, S.; Sajid, Z.; Ullah, N.; Qayyum, S.; Rahim, T.; Usman, M. S.; Ali, N.; Khan, I.; Pervez, K.; Sumaira, B.; Ali, N.; Sultana, N.; Tanoli, A. Y.; Islam, M.

10.1101/2021.03.01.433336 — genetics — Posted on 2021-03-01

4768 Novel newt regeneration genes regulate Wingless signaling to restore patterning in Drosophila eye

Mehta, A. S.; Deshpande, P.; Chimata, A. V.; Tsonis, P. A.; Singh, A.

10.1101/2021.02.28.433269 — developmental biology — Posted on 2021-03-01

4769 Disruption of the Pseudomonas aeruginosa Tat system perturbs PQS-dependent quorum sensing and biofilm maturation through loss of the Rieske cytochrome bc1 sub-unit

Soh, E. Y.-C.; Smith, F.; Gimenez, M.; Yang, L.; Vejborg, R.; Fletcher, M.; Halliday, N.; Bleves, S.; Heeb, S.; Camara, M.; Givskov, M.; Hardie, K.; Tolker-Nielsen, T.; Ize, B.; Williams, P.

10.1101/2021.03.01.433341 — microbiology — Posted on 2021-03-01

4770 Derivation and Characterization of an inositol phosphate-independent HIV-1

Poston, D.; Zang, T.; Bieniasz, P. D.

10.1101/2021.03.01.433343 — microbiology — Posted on 2021-03-01

4771 Protein phosphatase SppA regulates apical growth and dephosphorylates cell polarity determinant DivIVA in Streptomyces coelicolor

Passot, F.; Cantlay, S.; Flardh, K.

10.1101/2021.03.01.433328 — microbiology — Posted on 2021-03-01

4772 Sandalwood, an Indian medicinal plant attenuates the microbial growth and influence up/down regulation of the metabolites

Parveen, R.; Shamsi, T. N.; Fatima, S.

10.1101/2021.03.01.433331 — microbiology — Posted on 2021-03-01

4773 Enhanced preference for delayed rewards requires the basolateral amygdala and retrosplenial cortex

Lefner, M. J.; Magnon, A. P.; Gutierrez, J. M.; Lopez, M. R.; Wanat, M.

10.1101/2021.01.14.426754 — neuroscience — Posted on 2021-03-01

4774 A role for the immune system-released activating agent (ISRAA) in the ontogenetic development of brain astrocytes

Al-Awadi, A. M. I.; AlJawder, A. I.; Mousa, A.; Taha, S.; Bakhiet, M.

10.1101/2021.03.01.433338 — neuroscience — Posted on 2021-03-01

4775 Biotransformation of agro-industrial waste to wealth in Africa through mushroom farming

Ekun, V. S.; Adenipekun, C. O.; Idowu, O.; Etaware, P. M.

10.1101/2021.03.01.433330 — plant biology — Posted on 2021-03-01

4776 The time to peak blood bicarbonate (HCO3-), pH, and strong ion difference (SID) following sodium bicarbonate (NaHCO3) ingestion in highly trained adolescent swimmers

Newbury, J. W.; Cole, M.; Kelly, A. L.; Chessor, R. J.; Sparks, A.; McNaughton, L. R.; Gough, L. A.

10.1101/2021.03.01.433339 — physiology — Posted on 2021-03-01

4777 DNMT family induced down-regulation of NDRG1 via DNA methylation and clinicopathological significance in gastric cancer

Chang, x.; MA, J.; Xue, X.; Wang, G.; Su, L.; Han, X.; Zhou, H.; Hou, L.

10.1101/2021.03.01.433329 — cancer biology — Posted on 2021-03-01

Slater, L. T.; Karwath, A.; Williams, J. A.; Russell, S.; Makepeace, S.; Carberry, A.; Hoehndorf, R.; Gkoutos, G. V.

10.1101/2021.01.26.428269 — bioinformatics — Posted on 2021-03-01

4779 Self-Assembling Peptide Hydrogels - PeptiGels(R) as a Platform for Hepatic Organoid Culture

Olayanju, A.; Miller, A. F.; Ansari, T.; Goldring, C. E.

10.1101/2021.03.01.433333 — bioengineering — Posted on 2021-03-01

4780 Species-wide transposable element repertoires retrace the evolutionary history of the Saccharomyces cerevisiae host

Bleykasten, C.; Fabrizio, R.; Friedrich, A.; Schacherer, J.

10.1101/2021.03.01.433327 — genomics — Posted on 2021-03-01

4781 Evolutionary Analysis of Transcriptional Regulation Mediated by Cdx2 in Rodents

Liang, W.; Li, G.; Cui, H.; Wang, Y.; Wei, W.; Sun, S.; Gan, D.; Chen, R.; Yi, H.; Schaefke, B.; Hu, Y.; Zhou, Q.; Li, W.; Chen, W.

10.1101/2021.03.01.433326 — evolutionary biology — Posted on 2021-03-01

4782 Periodic synchronization of dengue epidemics in Thailand: the roles played by temperature and immunity

Garcia-Carreras, B.; Yang, B.; Grabowski, M. K.; Sheppard, L. W.; Huang, A. T.; Salje, H.; Clapham, H. E.; Iamsirithaworn, S.; Doung-Ngern, P.; Lessler, J.; Cummings, D. A. T.

10.1101/2021.03.01.433325 — ecology — Posted on 2021-03-01

4783 Countering reproducibility issues in mathematical models with software engineering techniques: A case study using a one-dimensional mathematical model of the atrioventricular node

Schölzel, C.; Blesius, V.; Ernst, G.; Goesmann, A.; Dominik, A.

10.1101/2021.02.19.431951 — systems biology — Posted on 2021-03-01

4784 Calprotectin-mediated zinc chelation inhibits Pseudomonas aeruginosa protease activity in cystic fibrosis sputum

Vermilyea, D. M.; Crocker, A. W.; Gifford, A. H.; Hogan, D. A.

10.1101/2021.02.25.432981 — microbiology — Posted on 2021-03-01

4785 A structural analysis of amyloid polymorphism in disease: clues for selective vulnerability?

Van Der Kant, R.; Louros, N.; Schymkowitz, J.; Rousseau, F.

10.1101/2021.03.01.433317 — neuroscience — Posted on 2021-03-01

4786 Constructing neural network models from brain data reveals representational transformations underlying adaptive behavior

Ito, T.; Yang, G. R.; Laurent, P.; Schultz, D. H.; Cole, M. W.

10.1101/2020.12.24.424353 — neuroscience — Posted on 2021-03-01

4787 MoBiFC: development of a modular bimolecular fluorescence complementation toolkit for the analysis of chloroplast protein-protein interactions.

Velay, F. R.; Soula, M.; Mehrez, M.; D'Alessandro, S.; Laloi, C.; Crete, P.; Field, B.

10.1101/2021.03.01.433373 — plant biology — Posted on 2021-03-01

4788 The plant immune receptors NRG1.1 and ADR1 are calcium influx channels

Jacob, P. M.; Kim, N. H.; Wu, F.; El Kasmi, F. M.; Walton, W. G.; Furzer, O. J.; Lietzan, A. D.; Sunil, S.; Kempthorn, K.; Redinbo, M.; Pei, Z.-M.; Wan, L.; Dangl, J. L.

10.1101/2021.02.25.431980 — plant biology — Posted on 2021-03-01

4789 Phosphatidylinositol phosphate binding domains exhibit complex dissociation properties at the inner leaflet of plasma membrane sheets

Sponholtz, M. R.; Senning, E. N.

10.1101/2021.02.17.431012 — biophysics — Posted on 2021-03-01

4790 A synthetic RNA-mediated evolution system in yeast

Jensen, E. D.; Laloux, M.; Lehka, B. J.; Pedersen, L. E.; Jakociunas, T.; Jensen, M. K.; Keasling, J. D.

10.1101/2021.02.27.433199 — bioengineering — Posted on 2021-03-01

4791 Non-Parametric Analysis of Inter-Individual Relations Using an Attention-Based Neural Network

Morita, T.; Toyoda, A.; Aisu, S.; Kaneko, A.; Suda-Hashimoto, N.; Adachi, I.; Matsuda, I.; Koda, H.

10.1101/2020.03.25.994764 — animal behavior and cognition — Posted on 2021-03-01

4792 A drastic shift in the energetic landscape of toothed whale sperm cells

Alves, L. Q.; Ruivo, R.; Valente, R.; Fonseca, M. M.; Machado, A. M.; Plon, S.; Monteiro, N.; Garcia-Parraga, D.; Ruiz-Diaz, S.; Sanchez-Calabuig, M. L.; Gutierrez-Adan, A.; Castro, F.

10.1101/2021.03.01.432277 — evolutionary biology — Posted on 2021-03-01

4793 RNA-sequencing indicates immune cell signaling and inflammatory gene expression in cardiac fibroblasts increases with developmental age

Perreault, L. R.; Le, T. T.; Oudin, M. J.; Black, L. D.

10.1101/2021.03.01.433442 — cell biology — Posted on 2021-03-01

4794 The Fkh1 Forkhead Associated Domain Promotes ORC Binding to a Subset of DNA Replication Origins in Budding Yeast

Hoggard, T.; Hollatz, A. J.; Cherney, R.; Fox, C. A.

10.1101/2021.03.01.433423 — molecular biology — Posted on 2021-03-01

4795 Molecular epidemiology of third-generation cephalosporin-resistant Enterobacteriaceae from Southeast Queensland, Australia

Stewart, A. G.; Price, E. P.; Schabacker, K.; Birikmen, M.; Harris, P. N.; Choong, K.; Subedi, S.; Sarovich, D. S.

10.1101/2020.02.20.958728 — microbiology — Posted on 2021-03-01

4796 Electron transfer proteins in gut bacteria yield metabolites that circulate in the host

Liu, Y.; Chen, H.; Van Treuren, W.; Hou, B.-H.; Higginbottom, S. K.; Sonnenburg, J. L.; Dodd, D.

10.1101/2019.12.11.873224 — microbiology — Posted on 2021-03-01

4797 Analysis of Classic Tomato Mutants Reveals Influence of Leaf Vein Density on Fruit BRIX

Cheng, Z.; Rowland, S. D.; Czarnecki, K.; Zumstein, K.; Nakayama, H.; Sinha, N. R.

10.1101/2021.03.01.433399 — plant biology — Posted on 2021-03-01

4798 Phosphate transporter genes: genome-wide identification and characterization in Camelina sativa

Hasanzadeh, S.; Faraji, S.; Abdullah, ; Heidari, P.

10.1101/2021.02.28.433256 — plant biology — Posted on 2021-03-01

4799 Copy number variant heterogeneity among cancer types reflects inconsistent concordance with diagnostic classifications

Carrio Cordo, P.; Baudis, M.

10.1101/2021.03.01.433348 — cancer biology — Posted on 2021-03-01

4800 Cryo-EM structure of lipid embedded human ABCA7 at 3.6 Å resolution

Le, L. T. M.; Thompson, J. R.; Aikawa, T.; Kanekiyo, T.; Alam, A.

10.1101/2021.03.01.433448 — biophysics — Posted on 2021-03-01

4801 The global carrier frequency and genetic prevalence of Upshaw-Schulman syndrome

Zhao, T.; Fan, S.; Sun, L.

10.1101/2021.02.28.433213 — bioinformatics — Posted on 2021-03-01

4802 Identify phage hosts from metaviromic short reads based on deep learning and Markov chain model

Tan, J.; Fang, Z.; Wu, S.; Guo, Q.; Jiang, X.; Zhu, H.

10.1101/2021.03.01.433351 — bioinformatics — Posted on 2021-03-01

4803 Processing variables of direct-write, near-field electrospinning impact size and morphology of gelatin fibers

Davis, Z. G.; Hussain, A. F.; Fisher, M. B.

10.1101/2020.09.17.301804 — bioengineering — Posted on 2021-03-01

4804 Confirmation bias optimizes reward learning

Tarantola, T. O.; Folke, T.; Boldt, A.; Perez, O. D.; De Martino, B.

10.1101/2021.02.27.433214 — animal behavior and cognition — Posted on 2021-03-01

4805 Leveraging three-dimensional chromatin architecture for effective reconstruction of enhancer-target gene regulatory network

Salviato, E.; Djordjilovic, V.; Hariprakash, J. M.; Tagliaferri, I.; Pal, K.; Ferrari, F.

10.1101/2021.03.01.432687 — genomics — Posted on 2021-03-01

4806 Genomic diversity of 39 samples of Pyropia species grown in Japan

Nagano, Y.; Kimura, K.; Kobayashi, G.; Kawamura, Y.

10.1101/2020.05.15.099044 — genomics — Posted on 2021-03-01

4807 Butterfly eyespots evolved via co-option of the antennal gene-regulatory network

Murugesan, S. N.; Connahs, H.; Matsuoka, Y.; Gupta, M. d.; Huq, M.; Gowri, V.; Monroe, S.; Deem, K. D.; Werner, T.; Tomoyasu, Y.; Monteiro, A.

10.1101/2021.03.01.429915 — evolutionary biology — Posted on 2021-03-01

4808 Quantifying shifts in natural selection on codon usagebetween protein regions: A population genetics approach

Cope, A. L.; Gilchrist, M. A.

10.1101/2020.12.18.423529 — evolutionary biology — Posted on 2021-03-01

4809 Host-mediated, cross-generational intraspecific competition in a herbivore species

Castagneyrol, B.; van Halder, I.; Kadiri, Y.; Schille, L.; Jactel, H.

10.1101/2020.07.30.228544 — ecology — Posted on 2021-03-01

4810 Mechanically Sensitive HSF1 is a Key Regulator of Left-Right Symmetry Breaking in Zebrafish Embryos

Du, J.; Li, S. K.; Guan, L.-Y.; Guo, Z.; Yin, J.-F.; Gao, L.; Kawanishi, T.; Shimada, A.; Zhang, Q.-p.; Zheng, L.-S.; Liu, Y.-Y.; Feng, X.-X.; Chen, D.-Y.; Takeda, H.; Fan, Y.

10.1101/2021.02.25.432863 — developmental biology — Posted on 2021-03-01

4811 Polymer physics and machine learning reveal a combinatorial code linking chromatin 3D architecture to 1D epigenetics

Esposito, A.; Bianco, S.; Chiariello, A. M.; Abraham, A.; Fiorillo, L.; Conte, M.; Campanile, R.; Nicodemi, M.

10.1101/2021.03.01.433416 — molecular biology — Posted on 2021-03-01

4812 CD47 as a potential biomarker for the early diagnosis of severe COVID-19

McLaughlin, K.-M.; Bojkova, D.; Bechtel, M.; Kandler, J.; Reus, P.; Le, T.; Wagner, J. U.; Ciesek, S.; Wass, M. N.; Michaelis, M.; Cinatl, J. N.

10.1101/2021.03.01.433404 — microbiology — Posted on 2021-03-01

4813 Mapping Twenty Years of Antimicrobial Resistance Research Trends

Luz, C. F.; van Niekerk, M.; Keizer, J.; Beerlage-de Jong, N.; Braakman-Jansen, A.; Stein, A.; Sinha, B.; van Gemert-Pijnen, L.; Glasner, C.

10.1101/2021.03.01.433375 — microbiology — Posted on 2021-03-01

4814 RecT recombinase expression enables efficient gene editing in Enterococcus

Chen, V.; Griffin, M. E.; Hang, H. C.

10.1101/2020.09.01.278044 — microbiology — Posted on 2021-03-01

4815 Non-canonical Hedgehog signaling through L-type voltage gated Ca2+ channels controls CD8+ T cell killing

Hanna, J.; Kapeni, C.; O'Brien, L.; Carbonaro, V.; Beke, F.; Chilamakuri, C.; de la Roche, M.

10.1101/2021.03.01.433424 — immunology — Posted on 2021-03-01

4816 Rapid selection of HIV envelopes that bind to neutralizing antibody B cell lineage members with functional improbable mutations

Swanson, O.; Rhodes, B.; Wang, A.; Shi-Mao, X.; Parks, R.; Sanzone, A.; Louder, M. K.; Lin, B. C.; Doria-Rose, N.; Bonsignori, M.; Saunders, K. O.; Wiehe, K.; Haynes, B. F.; Azoitei, M. L.

10.1101/2021.01.04.425252 — immunology — Posted on 2021-03-01

4817 Comparison of cerebrospinal fluid biomarkers relevant to neurodegenerative diseases in healthy cynomolgus and rhesus macaque monkeys

Robertson, E. L.; Boehnke, S. E.; Lyra e Silva, N. M.; Armitage-Brown, B.; Winterborn, A.; Cook, D. J.; De Felice, F. G.; Munoz, D. P.

10.1101/2021.03.01.433384 — neuroscience — Posted on 2021-03-01

4818 Electrophysiological Indicators of Sleep-associated Memory Consolidation in 5- to 6-Year-Old Children

Joechner, A.-K.; Wehmeier, S.; Werkle-Bergner, M.

10.1101/2020.09.04.283606 — neuroscience — Posted on 2021-03-01

4819 Reflections of Idiographic Long-Term Memory Characteristics In Resting-State Neuroimaging Data

Zhou, P.; Sense, F.; van Rijn, H.; Stocco, A.

10.1101/2020.04.18.047662 — neuroscience — Posted on 2021-03-01

4820 Characterization of induction methods for Drosophila seizure mutations

Mituzaite, J.; Petersen, R.; Claridge-Chang, A.; Baines, R. A.

10.1101/2021.03.01.433313 — neuroscience — Posted on 2021-03-01

4821 Narratives: fMRI data for evaluating models of naturalistic language comprehension

Nastase, S. A.; Liu, Y.-F.; Hillman, H.; Zadbood, A.; Hasenfratz, L.; Keshavarzian, N.; Chen, J.; Honey, C. J.; Yeshurun, Y.; Regev, M.; Nguyen, M.; Chang, C. H. C.; Baldassano, C.; Lositsky, O.; Simony, E.; Chow, M. A.; Leong, Y. C.; Brooks, P. P.; Micciche, E.; Choe, G.; Goldstein, A.; Vanderwal, T.; Halchenko, Y. O.; Norman, K. A.; Hasson, U.

10.1101/2020.12.23.424091 — neuroscience — Posted on 2021-03-01

4822 Visual Cortical Area MT is Required For Development of the Dorsal Stream and Associated Visuomotor Behaviours

Kwan, W. C.; Chang, C.-K.; Yu, H.-H.; Mundinano, I.-C. C.; Fox, D. M.; Homman-Ludiye, J.; Bourne, J.

10.1101/2021.02.28.433301 — neuroscience — Posted on 2021-03-01

4823 Medial prefrontal cortex has a causal role in selectively enhanced consolidation of emotional memories after a 24-hour delay: An iTBS study

Yeh, N.; Payne, J. D.; Kim, S. Y.; Kensinger, E. A.; Koen, J. D.; Rose, N. S.

10.1101/2020.10.11.335125 — neuroscience — Posted on 2021-03-01

4824 Granger Causality Inference in EEG Source Connectivity Analysis: A State-Space Approach

Manomaisaowapak, P.; Nartkulpat, A.; Songsiri, J.

10.1101/2020.10.07.329276 — neuroscience — Posted on 2021-03-01

4825 Practical Identifiability in the Frame of Nonlinear Mixed Effects Models: the Example of the in vitro Erythropoiesis

Duchesne, R.; Guillemin, A.; Gandrillon, O.; Crauste, F.

10.1101/2021.03.01.433388 — systems biology — Posted on 2021-03-01

4826 Dimensionality-Reduction in the Drosophila Wing as Revealed by Landmark-Free Measurements of Phenotype

Alba, V.; Carthew, J. E.; Carthew, R. W.; Mani, M.

10.1101/2020.10.13.333740 — systems biology — Posted on 2021-03-01

4827 Meta-Research: Citation needed? Wikipedia and the COVID-19 pandemic

Benjakob, O.; Aviram, R.; Sobel, J. A.

10.1101/2021.03.01.433379 — scientific communication and education — Posted on 2021-03-01

4828 Cinnamoyl-CoA Reductase 1 (CCR1) and CCR2 Function Divergently in Tissue Lignification, Flux Control and Cross-talk with Glucosinolate Pathway in Brassica napus

Yin, N.; Li, B.; Liu, X.; Liang, Y.; Lian, J.-P.; Xue, Y.; Qu, C.; Lu, K.; Wei, L.; Wang, R.; Li, J.; Chai, Y.-R.

10.1101/2021.03.01.433400 — plant biology — Posted on 2021-03-01

4829 Expression levels of long noncoding natural antisense transcripts overlapping the UGT73C6 gene affect rosette size of Arabidopsis thaliana

Meena, S. K.; Heidecker, M.; Engelmann, S.; Jaber, A.; de Vries, T.; Baumann-Kaschig, K.; Abel, S.; Behrens, S.-E.; Gago-Zachert, S.

10.1101/2021.03.01.433436 — plant biology — Posted on 2021-03-01

4830 Rapid stress hardening in the Antarctic midge improves male fertility by increasing courtship success and preventing the decline of accessory gland proteins following cold exposure

Ajayi, O. M.; Gantz, J. D.; Finch, G.; Lee, R. E.; Denlinger, D. L.; Benoit, J. B.

10.1101/2021.02.27.432016 — physiology — Posted on 2021-03-01

4831 Deep learning tools and modeling to estimate the temporal expression of E2Fs over the cell cycle from 2D still images

Pecot, T.; Cuitino, M. C.; Johnson, R. H.; Timmers, C.; Leone, G.

10.1101/2021.03.01.433386 — bioinformatics — Posted on 2021-03-01

4832 Structural O-Glycoform Heterogeneity of the SARS-CoV-2 Spike Protein Receptor-Binding Domain Revealed by Native Top-Down Mass Spectrometry

Roberts, D. S.; Mann, M. W.; Melby, J. A.; Larson, E. J.; Zhu, Y.; Brasier, A. R.; Jin, S.; Ge, Y.

10.1101/2021.02.28.433291 — biochemistry — Posted on 2021-03-01

4833 Day-night and seasonal variation of human gene expression across tissues

Wucher, V.; Sodaei, R.; Amador, R.; Irimia, M.; Guigo, R.

10.1101/2021.02.28.433266 — genomics — Posted on 2021-03-01

4834 The aging DNA methylome reveals environment-by-aging interactions in a model teleost

Bertucci, E. M.; Mason, M. W.; Rhodes, O. E.; Parrott, B. B.

10.1101/2021.03.01.433371 — genomics — Posted on 2021-03-01

4835 PRDM9 directs recombination hotspots to prevent competition with meiotic transcription

Schwarzkopf, E. J.; Cornejo, O. E.

10.1101/2021.03.01.433380 — genomics — Posted on 2021-03-01

4836 A Comparison of Performance for Different SARS-Cov-2 Sequencing Protocols

Bermudez, J.

10.1101/2021.03.01.433428 — genetics — Posted on 2021-03-01

4837 Arabidopsis ROOT UV-B SENSITIVE 1 and 2 Interact with Aminotransferases to Regulate Vitamin B6 Homeostasis

He, Z.-H.; Tong, H.; Leasure, C. D.; Yen, R.; Hou, X.; O'Neil, N.; Ting, D.; Sun, Y.; Zhang, S.-W.; Tang, Y.; Phan, S.; Ibarra, C.; Chang, J.-T.; Black, D.; McCray, T.; Perry, N.; Peng, X.; Lee, J.; Turcios, K.; Guliaev, A.; Duarte, E. M.

10.1101/2021.03.01.433438 — genetics — Posted on 2021-03-01

4838 Circular RNA repertoires are associated with evolutionarily young transposable elements

Gruhl, F.; Janich, P.; Kaessmann, H.; Gatfield, D.

10.1101/2021.03.01.433421 — evolutionary biology — Posted on 2021-03-01

4839 An evolutionary genomic approach reveals both conserved and species-specific genetic elements related to human disease in closely related Aspergillus fungi

Mead, M. E.; Steenwyk, J. L.; Silva, L. P.; de Castro, P. A.; Saeed, N.; Hillmann, F.; Goldman, G.; Rokas, A.

10.1101/2021.03.01.433394 — evolutionary biology — Posted on 2021-03-01

4840 Interaction of thyroid hormones and gonadotropin inhibitory hormone in the multifactorial control of zebrafish (Danio rerio) spermatogenesis

Rodrigues, M. S.; Fallah, H. P.; Zanardini, M.; Habibi, H. R.; Nobrega, R. H.

10.1101/2021.03.01.433429 — cell biology — Posted on 2021-03-01

4841 The E3 Ubiquitin Ligase RNF5 Facilitates SARS-CoV-2 Membrane Protein-Mediated Virion Release

Yuan, Z.; Ding, B.

10.1101/2021.02.28.433287 — microbiology — Posted on 2021-03-01

4842 Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell

Puray-Chavez, M.; Lapak, K. M.; Schrank, T. P.; Elliott, J. L.; Bhatt, D. P.; Agajanian, M. J.; Jasuja, R.; Lawson, D. Q.; Davis, K.; Rothlauf, P. W.; Jo, H.; Lee, N.; Tenneti, K.; Eschbach, J. E.; Shema Mugisha, C.; Vuong, H. R.; Bailey, A. L.; Hayes, D. N.; Whelan, S. P. J.; Horani, A.; Brody, S. L.; Goldfarb, D.; Major, M. B.; Kutluay, S. B.

10.1101/2021.03.01.433431 — microbiology — Posted on 2021-03-01

4843 C4-dicarboxylate metabolons: Interaction of C4-dicarboxylate transporters of Escherichia coli with cytosolic enzymes and regulators

Schubert, C.; Unden, G.

10.1101/2021.03.01.433382 — microbiology — Posted on 2021-03-01

4844 Negligible impact of SARS-CoV-2 variants on CD4+ and CD8+ T cell reactivity in COVID-19 exposed donors and vaccinees.

Tarke, A.; Sidney, J.; Methot, N.; Zhang, Y.; Dan, J. M.; Goodwin, B.; Rubiro, P.; Sutherland, A.; da Silva Antunes, R.; Fraizer, A.; Rawlings, S. A.; Smith, D. M.; Peters, B.; Scheuermann, R. H.; Weiskopf, D.; Crotty, S.; Grifoni, A.; Sette, A.

10.1101/2021.02.27.433180 — immunology — Posted on 2021-03-01

4845 Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains

Faulkner, N.; Ng, K.; Wu, M.; Harvey, R.; Hussain, S.; Greco, M.; Bolland, W.; Warchal, S.; Margaritis, M.; Paraskevopoulou, S.; Heaney, J.; Rickman, H.; Houlihan, C.; Spyer, M.; Frampton, D.; Byott, M.; de Oliveira, T.; Sigal, A.; Kjaer, S.; Swanton, C.; Gandhi, S.; Beale, R.; Gamblin, S.; Mccauley, J.; Daniels, R.; Howell, M.; Bauer, D.; Nastouli, E.; Kassiotis, G.

10.1101/2021.03.01.433314 — immunology — Posted on 2021-03-01

4846 Influence of basal media composition on barrier fidelity within human pluripotent stem cell-derived blood-brain barrier models

Neal, E.; Katdare, K.; Shi, Y.; Marinelli, N.; Hagerla, K.; Lippmann, E.

10.1101/2021.03.01.433282 — neuroscience — Posted on 2021-03-01

4847 In vitro screening of herbal medicinal products for their supportive curing potential in the context of SARS-CoV-2

Tran, H.; Peterburs, P.; Seibel, J.; Abramov-Sommariva, D.; Lamy, E.

10.1101/2021.03.01.433344 — pharmacology and toxicology — Posted on 2021-03-01

4848 Differential Dynamic Behavior of Prefusion Spike Proteins of SARS Coronaviruses 1 and 2

Govind Kumar, V.; Ogden, D. S.; Isu, U.; Polasa, A.; Losey, J.; Moradi, M.

10.1101/2020.12.25.424008 — biophysics — Posted on 2021-03-01

4849 The combined treatment of Molnupiravir and Favipiravir results in a marked potentiation of efficacy in a SARS-CoV2 hamster infection model through an increased frequency of mutations in the viral genome.

10.1101/2020.12.10.419242 — microbiology — Posted on 2021-03-01

4850 Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktail

Dong, J.; Zost, S.; Greaney, A.; Starr, T. N.; Dingens, A. S.; Chen, E. C.; Chen, R.; Case, B.; Sutton, R.; Gilchuk, P.; Rodriguez, J.; Armstrong, E.; Gainza, C.; Nargi, R.; Binshtein, E.; Xie, X.; Zhang, X.; Shi, P.-Y.; Logue, J.; Weston, S.; McGrath, M.; Frieman, M.; Brady, T.; Tuffy, K.; Bright, H.; Loo, Y.-M.; McvTamney, P.; Esser, M.; Carnahan, R.; Diamond, M.; Bloom, J.; Crowe, J. E.

10.1101/2021.01.27.428529 — immunology — Posted on 2021-03-01

4851 REDUCED ER-MITOCHONDRIA CONNECTIVITY PROMOTES NEUROBLASTOMA MULTIDRUG RESISTANCE

Coku, J.; Booth, D. M.; Skoda, J.; Pedrotty, M. C.; Vogel, J.; Liu, K.; Vu, A.; Carpenter, E. L.; Ye, J. C.; Chen, M. A.; Dunbar, P.; Scadden, E.; Nakamaru-Ogiso, E.; Li, Y.; Goldsmith, K. C.; Reynolds, C. P.; Hajnoczky, G.; Hogarty, M. D.

10.1101/2021.03.01.433120 — cancer biology — Posted on 2021-03-01

4852 Conformational changes in twitchin kinase in vivo revealed by FRET imaging of freely moving C. elegans

Porto, D.; Matsunaga, Y.; Franke, B.; Williams, R.; Qadota, H.; Mayans, O.; Benian, G. M.; Lu, H.

10.1101/2021.03.01.433414 — biophysics — Posted on 2021-03-01

4853 Immunoglobulin superfamily receptor Junctional adhesion molecule 3 (Jam3) requirement for melanophore survival and patterning during formation of zebrafish stripes

Eom, D. S.; Patterson, L. B.; Bostic, R. B.; Parichy, D. M.

10.1101/2021.03.01.433381 — developmental biology — Posted on 2021-03-01

4854 Delineating the complex mechanistic interplay between autophagy and monocyte to macrophage differentiation: a functional perspective

Bhattacharya, A.; Ghosh, P.; Singh, A.; Ghosh, A.; Bhowmick, A.; Sinha, D.; Ghosh, A.; Sen, P.

10.1101/2021.03.01.433396 — cell biology — Posted on 2021-03-01

4855 A ciliopathy complex builds distal appendages to initiate ciliogenesis

Kumar, D.; Rains, A.; Herranz-Perez, V.; Lu, Q.; Shi, X.; Swaney, D. L.; Stevenson, E.; Krogan, N. J.; Huang, B.; Westlake, C.; Garcia-Verdugo, J. M.; Yoder, B.; Reiter, J.

10.1101/2021.03.01.433418 — cell biology — Posted on 2021-03-01

4856 A novel splice variant of human TGF-β type II receptor encodes a soluble protein and its Fc-tagged version prevents liver fibrosis in vivo.

Bertolio, M. S.; La Colla, A.; Carrea, A.; Romo, A.; Canziani, G.; Echarte, S. M.; Campisano, S.; Barletta, G. P.; Monzon, A. M.; Rodriguez, T. M.; Chisari, A. N.; Dewey, R. A.

10.1101/2021.03.01.433173 — cell biology — Posted on 2021-03-01

4857 Immune complex solubility and size govern Fc-gamma receptor responses

Chen, H.; Maul-Pavicic, A.; Holzer, M.; Salzer, U.; Chevalier, N.; Voll, R. E.; Hengel, H.; Kolb, P.

10.1101/2020.11.11.378232 — immunology — Posted on 2021-03-01

4858 Effect of SARS-CoV-2 proteins on vascular permeability

Rauti, R.; Shahoha, M.; Leichtmann-Bardoogo, Y.; Nasser, R.; Tamir, R.; Miller, V.; Babich, T.; Shaked, K.; Ehrlich, A.; Ioannidis, K.; Nahmias, Y.; Sharan, R.; Ashery, U.; Maoz, B. M.

10.1101/2021.02.27.433186 — cell biology — Posted on 2021-03-01

4859 Ultrapotent miniproteins targeting the receptor-binding domain protect against SARS-CoV-2 infection and disease in mice

Case, J. B.; Chen, R. E.; Cao, L.; Ying, B.; Winkler, E. S.; Goreshnik, I.; Shrihari, S.; Kafai, N. M.; Bailey, A. L.; Xie, X.; Shi, P.-Y.; Ravichandran, R.; Carter, L.; Stewart, L.; Baker, D.; Diamond, M. S.

10.1101/2021.03.01.433110 — microbiology — Posted on 2021-03-01

4860 Mice immunized with the vaccine candidate HexaPro spike produce neutralizing antibodies against SARS-CoV-2

Seephetdee, C.; Buasri, N.; Bhukhai, K.; Srisanga, K.; Manopwisedjaroen, S.; Lertjintanakit, S.; Phueakphud, N.; Pakiranay, C.; Kangwanrangsan, N.; Srichatrapimuk, S.; Sungkanuparph, S.; Kirdlarp, S.; Chutipongtanate, S.; Thitithanyanont, A.; Hongeng, S.; Wongtrakoongate, P.

10.1101/2021.02.27.433054 — immunology — Posted on 2021-03-01

4861 Discovery of re-purposed drugs that slow SARS-CoV-2 replication in human cells

Pickard, A.; Calverley, B. C.; Chang, J.; Garva, R.; Lu, Y.; Kadler, K. E.

10.1101/2021.01.31.428851 — immunology — Posted on 2021-03-01

4862 Biological networks with singular Jacobians: their origins and adaptation criteria

Oellerich, T. G.; Emelianenko, M.; Liotta, L.; Araujo, R. P.

10.1101/2021.03.01.433197 — systems biology — Posted on 2021-03-01

4863 A Universal Chemical Method for Rational Design of Protein-based Nanoreactors

Reddy, M. M.; Bathla, P.; Sandanaraj, B. S.

10.1101/2021.03.01.433350 — synthetic biology — Posted on 2021-03-01

4864 Serotonin signaling modulates aging-associated metabolic network integrity in response to nutrient choice

Lyu, Y.; Promislow, D. E.; Pletcher, S.

10.1101/2021.03.01.433267 — genetics — Posted on 2021-03-01

4865 Butterfly eyespots evolved via co-option of the antennal gene-regulatory network

Murugesan, S. N.; Connahs, H.; Matsuoka, Y.; Gupta, M. d.; Huq, M.; Gowri, V.; Monroe, S.; Deem, K. D.; Werner, T.; Tomoyasu, Y.; Monteiro, A.

10.1101/2021.03.01.429915 — evolutionary biology — Posted on 2021-03-01

4866 miRNA-dependent poly(A) length control in uncoupling transcription and translation of haploid male germ cells

Tang, C.; Guo, M.; Shi, Z.; Wang, Z.; Luo, C.; Chen, S.; Ruan, F.; Chen, Z.; Yang, L.; Wei, X.; Wu, C.; Luo, B.; Huang, J.; Zhang, D.; Yu, C.; Gao, Q.; Zhang, Y.; Yan, W.; Sun, F.

10.1101/2021.03.01.433315 — molecular biology — Posted on 2021-03-01

4867 Increased transmission of SARS-CoV-2 lineage B.1.1.7 (VOC 2020212/01) is not accounted for by a replicative advantage in primary airway cells or antibody escape

Brown, J. C.; Goldhill, D. H.; Zhou, J.; Peacock, T. P.; Frise, R.; Goonawardane, N.; Baillon, L.; Kugathasan, R.; Pinto, A.; McKay, P. F.; Hassard, J.; Moshe, M.; Singanayagam, A.; Burgoyne, T.; the ATACCC Investigators, ; PHE Virology Consortium, ; Barclay, W. S.

10.1101/2021.02.24.432576 — microbiology — Posted on 2021-03-01

4868 Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interaction

Guimond, S. E.; Mycroft-West, C. J.; Gandhi, N. S.; Tree, J. A.; Le, T. T.; Spalluto, C. M.; Humbert, M. V.; Buttigieg, K. R.; Coombes, N.; Elmore, M. J.; Nystrom, K.; Said, J.; Setoh, Y. X.; Amarilla, A.; Modhiran, N.; Sng, D. J. J.; Chhabra, M.; Young, P. R.; Lima, M. A.; Su, D.; Yates, E. A.; Karlsson, R.; Miller, R. L.; Chen, Y.-H.; Bagdonaite, I.; Zhang, Y.; Stewart, J. P.; Hammond, E.; Dredge, K.; Wilkinson, T. M. A.; Watterson, D.; Khromykh, A. A.; Suhrbier, A.; Carroll, M. W.; Trybala, E.; Bergstrom, T.; Ferro, V.; Skidmore, M. A.; Turnbull, J. E.

10.1101/2020.06.24.169334 — microbiology — Posted on 2021-03-01

4869 Antibodies with potent and broad neutralizing activity against antigenically diverse and highly transmissible SARS-CoV-2 variants

Wang, L.; Zhou, T.; Zhang, Y.; Yang, E. S.; Schramm, C. A.; Shi, W.; Pegu, A.; Oloninyi, O. K.; Ransier, A.; Darko, S.; Narpala, S. R.; Hatcher, C.; Martinez, D. R.; Tsybovsky, Y.; Phung, E.; Abiona, O. M.; Cale, E. M.; Chang, L. A.; Corbett, K. S.; DiPiazza, A. T.; Gordon, I. J.; Leung, K.; Liu, T.; Mason, R. D.; Nazzari, A.; Novik, L.; Olia, A. S.; Stephens, T.; Stringham, C. D.; Talana, C. A.; Teng, I.-T.; Wagner, D.; Widge, A. T.; Zhang, B.; Roederer, M.; Ledgerwood, J. E.; Ruckwardt, T. J.; Gaudinski, M. R.; Baric, R. S.; Graham, B. S.; McDermott, A. B.; Douek, D. C.; Kwong, P. D.; Mascol

10.1101/2021.02.25.432969 — immunology — Posted on 2021-03-01

4870 SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

Wibmer, C. K.; Ayres, F.; Hermanus, T.; Madzivhandila, M.; Kgagudi, P.; Oosthuysen, B.; Lambson, B. E.; de Oliveira, T.; Vermeulen, M.; van den Berg, K.; Rossouw, T.; Boswell, M.; Ueckermann, V.; Meiring, S.; von Gottberg, A.; Cohen, C.; Morris, L.; Bhiman, J. N.; Moore, P. L.

10.1101/2021.01.18.427166 — immunology — Posted on 2021-03-01

4871 Bayesian MEG time courses with fMRI priors

Wang, Y.; Holland, S. K.

10.1101/2021.02.28.433293 — neuroscience — Posted on 2021-03-01

4872 Dynamic signatures of the Eureka effect: An EEG study

Lu, Y.; Singer, W.

10.1101/2021.02.27.433162 — neuroscience — Posted on 2021-03-01

4873 Direct cochlear recordings show human hearing nerve activity is modulated by selective attention

Gehmacher, Q.; Reisinger, P.; Hartmann, T.; Keintzel, T.; Rösch, S.; Schwarz, K.; Weisz, N.

10.1101/2021.03.01.433316 — neuroscience — Posted on 2021-03-01

4874 Placental uptake and metabolism as determinants of pregnancy vitamin D status

10.1101/2021.03.01.431439 — physiology — Posted on 2021-03-01

4875 Avalanches During Epithelial Tissue Growth; Uniform Growth and a Drosophila Eye Disc Model

Courcoubetis, G.; Xu, C.; Nuzhdin, S. V.; Haas, S.

10.1101/2021.03.01.433318 — biophysics — Posted on 2021-03-01

4876 MetaFetcheR: An R package for complete mapping of small compound data

Yones, S.; Csombordi, R.; Komorowski, J.; Diamanti, K.

10.1101/2021.02.28.433248 — bioinformatics — Posted on 2021-03-01

4877 The global carrier frequency and genetic prevalence of Upshaw-Schulman syndrome

Zhao, T.; Fan, S.; Sun, L.

10.1101/2021.02.28.433213 — bioinformatics — Posted on 2021-03-01

4878 Assessing heterogeneity in spatial data using the HTA index with applications to spatial transcriptomics and imaging

Levy-Jurgenson, A.; Tekpli, X.; Yakhini, Z.

10.1101/2021.02.28.433250 — bioinformatics — Posted on 2021-03-01

4879 The openCARP Simulation Environment for Cardiac Electrophysiology

Plank, G.; Loewe, A.; Neic, A.; Augustin, C.; Huang, Y.-L.; Gsell, M. A. F.; Karabelas, E.; Nothstein, M.; Sanchez, J.; Prassl, A. J.; Seemann, G.; Vigmond, E. J.

10.1101/2021.03.01.433036 — bioinformatics — Posted on 2021-03-01

4880 MXtrodes: MXene-infused bioelectronic interfaces for multiscale electrophysiology and stimulation

Driscoll, N.; Erickson, B.; Murphy, B. B.; Richardson, A. G.; Robbins, G.; Apollo, N. V.; Mathis, T.; Hantanasirisakul, K.; Bagga, P.; Gullbrand, S. E.; Sergison, M.; Reddy, R.; Wolf, J. A.; Chen, H. I.; Lucas, T. H.; Dillingham, T.; Davis, K. A.; Gogotsi, Y.; Medaglia, J. D.; Vitale, F.

10.1101/2021.03.01.433237 — bioengineering — Posted on 2021-03-01

4881 Lantern shark Etmopterus use coelenterazine as substrate for their luciferin-luciferase bioluminescence system

Mizuno, G.; Yano, D.; Paitio, J.; Endo, H.; Oba, Y.

10.1101/2021.03.01.433353 — biochemistry — Posted on 2021-03-01

4882 Playing soft with cooperators emerges as a moral norm and promotes cooperation in evolutionary games

Salahshour, M.

10.1101/2021.03.01.433361 — evolutionary biology — Posted on 2021-03-01

4883 Dissecting the genetic architecture of quantitative traits using genome-wide identity-by-descent sharing among full-sibs

Fraimout, A.; Li, Z.; Sillanpaa, M. J.; Rastas, P.; Merila, J.

10.1101/2021.03.01.432833 — evolutionary biology — Posted on 2021-03-01

4884 The status of current and tentative marine natural World Heritage areas

Kuempel, C.; Simmons, B. A.; Davey, M.

10.1101/2021.02.28.433275 — ecology — Posted on 2021-03-01

4885 Combined effects of salinity and temperature on grazing activity of invasive Gammarus tigrinus on charophytes

Berthold, M.; Porsche, C.; Hofmann, A.; Nowak, P.

10.1101/2021.03.01.433077 — ecology — Posted on 2021-03-01

4886 Molecular diet analysis in zebra and quagga mussels (Dreissena spp.) and an assessment of the utility of aquatic filter feeders as biological eDNA filters

Weber, S.; Brink, L.; Woerner, M.; Kuenzel, S.; Veith, M.; Teubner, D.; Klein, R.; Paulus, M.; Krehenwinkel, H.

10.1101/2021.03.01.432951 — ecology — Posted on 2021-03-01

4887 BMP signaling is necessary and sufficient for osteoarthritis and a target for disease modifying therapy

Jaswal, A. P.; Roelofs, A. J.; Singh, A. K.; Kumar, B.; Riemen, A. H. K.; Wang, H.; Sadaf, A.; Nanasaheb, S. V.; Iqbal, S. F.; Agnihotri, N.; De Bari, C.; Bandyopadhyay, A.

10.1101/2021.03.01.433366 — developmental biology — Posted on 2021-03-01

4888 Kinesin-4 Motor Teams Effectively Navigate Dendritic Microtubule Arrays Through Track Switching and Regulation of Microtubule Dynamics

Masucci, E. M.; Relich, P. K.; Lakadamyali, M.; Ostap, E. M.; Holzbaur, E. L. F.

10.1101/2021.02.28.433181 — cell biology — Posted on 2021-03-01

4889 CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre

Imasaki, T.; Kikkawa, S.; Niwa, S.; Saijo-Hamano, Y.; Shigematsu, H.; Aoyama, K.; Mitsuoka, K.; Aoki, M.; Sakamot, A.; Tomabechi, Y.; Sakai, N.; Shirouz, M.; Taguchi, S.; Yamagish, Y.; Setsu, T.; Sakihama, Y.; Shimizu, T.; Nitta, E.; Takeichi, M.; Nitta, R.

10.1101/2021.03.01.433304 — cell biology — Posted on 2021-03-01

4890 Human iPSC-derived renal cells change their immunogenic properties during maturation: Implications for regenerative therapies

Rossbach, B.; Hariharan, K.; Mah, N.; Oh, S. J.; Volk, H.-D.; Reinke, P.; Kurtz, A.

10.1101/2021.03.01.432225 — cell biology — Posted on 2021-03-01

4891 The Mechanism of Neurite Outgrowth Induction by Novel Synthetic Retinobenzoic Acids

Zhang, Y.; Yoshimi, Y.; Funatsu, O.; Hayashi, R.; Komagawa, S.; Saito, S.; Nagahara, Y.; Ikekita, M.

10.1101/2021.03.01.429320 — cell biology — Posted on 2021-03-01

4892 Molecular Basis for Reduced Cleavage Activity and Drug Resistance in D30N HIV-1 protease

Bihani, S. C.; Hosur, M. V.

10.1101/2021.02.28.433284 — molecular biology — Posted on 2021-03-01

4893 Reverse complementary matches simultaneously promote both back-splicing and exon-skipping

Cao, D.

10.1101/2021.02.28.433292 — molecular biology — Posted on 2021-03-01

4894 The establishment of variant surface glycoprotein monoallelic expression revealed by single-cell RNA-seq of Trypanosoma brucei in the tsetse fly salivary glands.

Hutchinson, S.; Foulon, S.; Crouzols, A.; Menafra, R.; Rotureau, B.; Griffiths, A. D.; Bastin, P.

10.1101/2021.03.01.433049 — molecular biology — Posted on 2021-03-01

4895 Host-derived Reactive Nitrogen Species mediate the Cryptococcus neoformans yeast-to-titan switch via fungal-derived superoxide

Zhou, X.; Desanti, G. E.; May, R. C.; Dambuza, I. M.; Ballou, E. R.

10.1101/2021.03.01.433276 — microbiology — Posted on 2021-03-01

4896 Development of a chemiluminescence immunoassay to accurately detect African swine fever virus antibodies in serum

Yang, Y.; Lv, C.; Fan, J.; Zhao, Y.; Jiang, L.; Sun, X.; Jin, M.; Zhao, Q.

10.1101/2021.02.28.433302 — microbiology — Posted on 2021-03-01

4897 Multiple evolutionary origins reflect the importance of sialic acid transporters in the colonisation potential of bacterial pathogens and commensals.

Severi, E.; Rudden, M.; Bell, A.; Palmer, T.; Juge, N.; Thomas, G. H.

10.1101/2021.03.01.433349 — microbiology — Posted on 2021-03-01

4898 The component parts of bacteriophage virions accurately defined by a machine-learning approach built on evolutionary features.

Thung, T. Y.; White, M. E.; Dai, W.; Wilksch, J. J.; Bamert, R. S.; Rocker, A.; Stubenrauch, C. J.; Williams, D.; Huang, C.; Schittelhelm, R. B.; Barr, J. J.; Jameson, E.; McGowan, S.; Zhang, Y.; Wang, J.; Dunstan, R. A.; Lithgow, T.

10.1101/2021.02.28.433281 — microbiology — Posted on 2021-03-01

4899 Therapeutic immunization against Helicobacter pylori infection in BALB/c mice induced by a multi-epitope vaccine based on computer-aided design

Ma, J.; Wang, S.; Ji, Q.; Liu, Q.

10.1101/2021.02.28.433231 — immunology — Posted on 2021-03-01

4900 Infusion of CCR5 Gene-Edited T Cells Allows Immune Reconstitution, HIV Reservoir Decay, and Long-Term Virological Control

Zeidan, J.; Sharma, A. A.; Lee, G.; Raad, A.; Fromentin, R.; Fourati, S.; Ghneim, K.; Sanchez, G. P.; Benne, C.; Canderan, G.; Procopio, F. A.; Balderas, R.; Monette, G.; Lalezari, J. P.; Heffernan, J. M.; Sabbagh, L.; Chomont, N.; Ando, D.; Deeks, S. G.; Sekaly, R.-P.

10.1101/2021.02.28.433290 — immunology — Posted on 2021-03-01

4901 Antibody response patterns to Helicobacter pylori infection in a rural Ugandan population cohort.

Sallah, N.; Hayes, A.; Osei-Tutu, N.; Johnston, T.; Asiki, G.; Butt, J.; Hibberd, M. L.; Waterboer, T.; Newton, R.

10.1101/2021.03.01.433355 — immunology — Posted on 2021-03-01

4902 A BCI-based vibrotactile neurofeedback training improves motor cortical excitability during motor imagery

Grigorev, N.; Savosenkov, A.; Lukoyanov, M.; Udoratina, A.; Shusharina, N.; Kaplan, A.; Hramov, A.; Kazantsev, V.; Gordleeva, S.

10.1101/2021.02.28.433220 — neuroscience — Posted on 2021-03-01

4903 Synergistic positive feedback underlying seizure initiation

Graham, R. T.; Parrish, R. R.; Alberio, L.; Johnson, E. L.; Owens, L. J.; Trevelyan, A. J.

10.1101/2021.02.28.433224 — neuroscience — Posted on 2021-03-01

4904 Beyond colour gamuts: Novel metrics for thereproduction of photoreceptor signals

Hexley, A. C.; Morimoto, T.; Spitschan, M.; Smithson, H. E.

10.1101/2021.02.27.433203 — neuroscience — Posted on 2021-03-01

4905 Episodic memory in aspects of brain information transfer by resting-state network topology

Yan, T.; Wang, G.; Wang, L.; Liu, T.; Li, T.; Wang, L.; Suo, D.; Funahashi, S.; Chen, D.; Wang, B.; Wu, J.

10.1101/2021.02.28.433300 — neuroscience — Posted on 2021-03-01

4906 VISUAL CORTICAL AREA MT IS REQUIRED FOR DEVELOPMENT OF THE DORSAL STREAM AND ASSOCIATED VISUOMOTOR BEHAVIOURS

Bourne, J.; Kwan, W. C.; Mundinano, I.-C. C.; Yu, H.-H.; Homman-Ludiye, J.; Fox, D. M.; Chang, C.-K.

10.1101/2021.02.28.433301 — neuroscience — Posted on 2021-03-01

4907 A structural analysis of amyloid polymorphism in disease: clues for selective vulnerability?

Van Der Kant, R.; Louros, N.; Schymkowitz, J.; Rousseau, F.

10.1101/2021.03.01.433317 — neuroscience — Posted on 2021-03-01

4908 Selective attention and decision-making have separable neural bases in space and time

Moerel, D.; Rich, A. N.; Woolgar, A.

10.1101/2021.02.28.433294 — neuroscience — Posted on 2021-03-01

4909 Brain Dynamics of Spatial Reference Frame Proclivity in Active Navigation

Yang, C.-S.; Liu, J.; Singh, A.; Huang, K.-C.; Lin, C.-T.

10.1101/2021.02.28.433279 — neuroscience — Posted on 2021-03-01

4910 Savings in human force field learning supported by feedback adaptation

Mathew, J.; Lefevre, P.; Crevecoeur, F.

10.1101/2021.03.01.433364 — neuroscience — Posted on 2021-03-01

4911 GPRuler: metabolic Gene-Protein-Reaction rules automatic reconstruction

Di Filippo, M.; Damiani, C.; Pescini, D.

10.1101/2021.02.28.433152 — systems biology — Posted on 2021-03-01

4912 Transfer learning framework for cell segmentationwith incorporation of geometric features

Jin, Y.; Toberoff, A.; Azizi, E.

10.1101/2021.02.28.433289 — systems biology — Posted on 2021-03-01

4913 Gibberellins target shoot-root growth, morpho-physiological and molecular pathways to induce cadmium tolerance in mung bean

Hakla, H. R.; Sharma, S.; Urfan, M.; Kotwal, D.; Yadav, N. S.; PAL, S.

10.1101/2021.02.28.433230 — plant biology — Posted on 2021-03-01

4914 Intravital imaging of real-time endogenous actin dysregulation in proximal and distal tubules at the onset of severe ischemia-reperfusion injury

Corridon, P. R.; Karam, S. H.; Khraibi, A. A.; Khan, A. A.; Alhashmi, M. A.

10.1101/2021.03.01.433337 — physiology — Posted on 2021-03-01

4915 Dual Drug Targeting to Kill Colon Cancer Cells

Burgess, A. W.; Faux, M. C.; Corona, S. P.; Weinstock, J.; Lessene, G.; Walker, F.

10.1101/2021.02.28.433288 — cancer biology — Posted on 2021-03-01

4916 RHAMMB-mediated bifunctional nanotherapy targeting Bcl-xL and mitochondria for pancreatic neuroendocrine tumor treatment

Chen, X.; Lee, S. K.; Song, M.; Zhang, T.; Han, M. S.; Chen, Y.-T.; Chen, Z.; Ma, X.; Tung, C.-H.; Du, Y.-C. N.

10.1101/2021.02.28.432124 — cancer biology — Posted on 2021-03-01

4917 Are adaptive chemotherapy schedules robust? A three-strategy stochastic evolutionary game theory model

Dua, R.; Ma, Y.; Newton, P. K.

10.1101/2021.02.28.433232 — biophysics — Posted on 2021-03-01

4918 Open Natural Products Research: Curation and Dissemination of Biological Occurrences of Chemical Structures through Wikidata

Rutz, A.; Sorokina, M.; Galgonek, J.; Mietchen, D.; Willighagen, E.; Graham, J. G.; Stephan, R.; Page, R.; Vondrasek, J.; Steinbeck, C.; Pauli, G.; Wolfender, J.-L.; Bisson, J.; Allard, P.-M.

10.1101/2021.02.28.433265 — bioinformatics — Posted on 2021-03-01

4919 ksrates: positioning whole-genome duplications relative to speciation events using rate-adjusted mixed paralog-ortholog KS distributions

Sensalari, C.; Maere, S.; Lohaus, R.

10.1101/2021.02.28.433234 — bioinformatics — Posted on 2021-03-01

4920 Small Directional Treadmill Perturbations Induce Differential Gait Stability Adaptation

Li, J.; Huang, H. J.

10.1101/2021.02.27.433210 — bioengineering — Posted on 2021-03-01

4921 ProxLogs: Miniaturised proximity loggers for monitoring association behaviour in small mammals

Kirkpatrick, L.; Hererra-Olivares, I.; Sabuni, C.; Massawe, A.; Leirs, H.; Berkvens, R.; Weyn, M.

10.1101/2021.02.28.432842 — animal behavior and cognition — Posted on 2021-03-01

4922 Male attention allocation depends on social context

Burridge, S. D.; Schlupp, I.; Makowicz, A. M.

10.1101/2021.02.27.433194 — animal behavior and cognition — Posted on 2021-03-01

4923 Confirmation bias optimizes reward learning

Tarantola, T. O.; Folke, T.; Boldt, A.; Perez, O. D.; De Martino, B.

10.1101/2021.02.27.433214 — animal behavior and cognition — Posted on 2021-03-01

4924 CORO2A, AN EXPRESSION QUANTITATIVE TRAIT GENE UNDERLYING ESTQ1, CONTROLS UTERINE RESPONSIVENESS TO ESTRADIOL

Findley, J.; McGee, E.; Lin, C.-Y.; Krementsov, D.; Teuscher, C.

10.1101/2021.02.28.433254 — genetics — Posted on 2021-03-01

4925 Origin and fate of supergenes in Atlantic cod

Matschiner, M.; Barth, J. M. I.; Torresen, O. K.; Star, B.; Baalsrud, H. T.; Brieuc, M. S. O.; Pampoulie, C.; Bradbury, I.; Jakobsen, K. S.; Jentoft, S.

10.1101/2021.02.28.433253 — evolutionary biology — Posted on 2021-03-01

4926 Delivering on Biden's 2030 conservation commitment

Simmons, B. A.; Nolte, C.; McGowan, J.

10.1101/2021.02.28.433244 — ecology — Posted on 2021-03-01

4927 A whole-brain imaging-based systems approach to understand origin of addiction in binge-like drinking model

Stefaniuk, M.; Monika, P.; Klaudia, N.; Baranski, M.; Zielinski, Z.; Bijoch, Łukasz; Legutko, D.; Majka, P.; Bednarek, S.; Jermakow, N.; Wojcik, D.; Kaczmarek, L.

10.1101/2021.02.17.431586 — neuroscience — Posted on 2021-03-01

4928 Discrimination of melanoma cell lines with Fourier Transform Infrared (FTIR) spectroscopy

Shakya, B. R.; Teppo, H.-R.; Rieppo, L.

10.1101/2020.09.05.284141 — bioinformatics — Posted on 2021-03-01

4929 Fast Alignment-Free Similarity Estimation By Tensor Sketching

Joudaki, A.; Ratsch, G.; Kahles, A.

10.1101/2020.11.13.381814 — bioinformatics — Posted on 2021-03-01

4930 Why do some primate mothers carry their infant's corpse? A cross-species comparative study

Fernandez-Fueyo, E.; Sugiyama, Y.; Matsui, T.; Carter, A. J.

10.1101/2021.01.12.426348 — animal behavior and cognition — Posted on 2021-03-01

4931 How robust are cross-population signatures of polygenic adaptation in humans?

Refoyo-Martinez, A.; Liu, S.; Jorgensen, A. M.; Jin, X.; Albrechtsen, A.; Martin, A. R.; Racimo, F.

10.1101/2020.07.13.200030 — genetics — Posted on 2021-03-01

4932 Defining the early stages of intestinal colonisation by whipworms

Duque Correa, M. A.; Goulding, D.; Rodgers, F.; Cormie, C.; Rawlinson, K. A.; Gillis, A.; Bancroft, A. J.; Bennett, H. M.; Lotkowska, M.; Reid, A. J.; Speak, A. O.; Scott, P.; Redshaw, N.; McCarthy, C.; Brandt, C.; Sharpe, C.; Ridley, C.; Gali Moya, J.; Carneiro, C. M.; Starborg, T.; Hayes, K. S.; Holroyd, N.; Sanders, M.; Thornton, D. J.; Grencis, R. K.; Berriman, M.

10.1101/2020.08.21.261586 — immunology — Posted on 2021-03-01

4933 Connectivity dynamics of the Default Mode Network encode the stream of affect at multiple timescales

Lettieri, G.; Handjaras, G.; Setti, F.; Cappello, E. M.; Bruno, V.; Diano, M.; Leo, A.; Ricciardi, E.; Pietrini, P.; Cecchetti, L.

10.1101/2020.06.06.137851 — neuroscience — Posted on 2021-03-01

4934 Listeners with congenital amusia are sensitive to context uncertainty in melodic sequences

Quiroga-Martinez, D. R.; Tillmann, B.; Brattico, E.; Cholvy, F.; Fornoni, L.; Vuust, P.; Caclin, A.

10.1101/2020.07.07.191031 — neuroscience — Posted on 2021-03-01

4935 Multi-scale brain simulation with integrated positron emission tomography yields hidden local field potential activity that augments machine-learning classification of Alzheimer's disease

Triebkorn, P.; Stefanovski, L.; Dhindsa, K.; Diaz-Cortes, M.-A.; Bey, P.; Bülau, K.; Pai, R. K.; Spiegler, A.; Solodkin, A.; Jirsa, V.; McIntosh, R.; Ritter, P.; Alzheimer's Disease Neuroimaging Initiative,

10.1101/2021.02.27.433161 — neuroscience — Posted on 2021-03-01

4936 Dynamic influences on static measures of metacognition

Desender, K.; Vermeylen, L.; Verguts, T.

10.1101/2020.10.29.360453 — neuroscience — Posted on 2021-03-01

4937 The Oscillatory Effects of Rhythmic Median Nerve Stimulation

Houlgreave, M. S.; Morera Maiquez, B.; Brookes, M. J.; Jackson, S. R.

10.1101/2020.10.23.348268 — neuroscience — Posted on 2021-03-01

4938 Considerations for MESF-bead based assignment of absolute fluorescence values to nanoparticles and extracellular vesicles by flow cytometry

Lozano-Andres, E.; Van Den Broeck, T.; Wang, L.; Mehrpouyan, M.; Tian, Y.; Yan, X.; Wauben, M. H. M.; Arkesteijn, G. J. A.

10.1101/2021.03.01.433358 — biophysics — Posted on 2021-03-01

4939 Dynamic Consequences of Specificity within the Cytidine Repressor DNA-Binding Domain

Moody, C. L.; Soto, J.; Tretyachenko-Ladokhina, V.; Senear, D. F.; Cocco, M. J.

10.1101/2021.02.28.433298 — biophysics — Posted on 2021-03-01

4940 Kinetic pathway of ATP-induced DNA interactions of ParA2, a protein essential for segregation of Vibrio cholerae chromosome 2

Chodha, S. S.; Brooks, A. C.; Davis, P. J.; Ramachandran, R.; Chattoraj, D. K.; Hwang, L. C.

10.1101/2021.02.27.433207 — biochemistry — Posted on 2021-03-01

4941 Sex-specific phenotypic effects and evolutionary history of an ancient polymorphic deletion of the human growth hormone receptor

Saitou, M.; Resendez, S.; Pradhan, A. J.; Wu, F.; Lie, N. C.; Hall, N. J.; Zhu, Q.; Reinholdt, L.; Satta, Y.; Nakagome, S.; Hanchard, N. A.; Churchill, G.; Lee, C.; Atilla-Gokcumen, G. E.; Mu, X.; Gokcumen, O.

10.1101/788653 — evolutionary biology — Posted on 2021-03-01

4942 Transcriptomic analysis of loss of Gli1 in neural stem cells responding to demyelination in the mouse brain

Samanta, J.; Salzer, J. L.

10.1101/2021.02.28.433246 — neuroscience — Posted on 2021-03-01

4943 Dissociation of tic expression from its neuronal encoding in the striatum during sleep

Vinner Harduf, E.; Matzner, A.; Belelovsky, K.; Bar-Gad, I.

10.1101/2020.06.29.176974 — neuroscience — Posted on 2021-03-01

4944 Towards 3D-Bioprinting of an Endocrine Pancreas: A Building-Block Concept for Bioartificial Insulin-Secreting Tissue

Salg, G. A.; Poisel, E.; Neulinger-Munoz, M.; Cebulla, D.; Vieira, V.; Bludszuweit-Philipp, C.; Nickel, F.; Herr, I.; Giese, N. A.; Hackert, T.; Kenngott, H. G.

10.1101/2021.02.27.433164 — bioengineering — Posted on 2021-03-01

4945 Photochromic fluorophores enable imaging of lowly-expressed proteins in the autofluorescent fungus Candida albicans

Van Genechten, W.; Demuyser, L.; Duwe, S.; Vandenberg, W.; Van Dijck, P.; Dedecker, P.

10.1101/2021.02.26.433138 — cell biology — Posted on 2021-03-01

4946 Emergence of a Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae Co-harbouring a blaNDM-1-carrying Virulent Plasmid and a blaKPC-2-carrying Plasmid in an Egyptian Hospital

El-Sayed Ahmed, M. A. E.-G.; Yang, Y.; Yang, Y.; Yan, B.; Chen, G.; Hassan, R. M.; Zhong, L.-l.; Chen, Y.; Roberts, A. P.; Wu, Y.; He, R.; Liang, X.; Qin, M.; Dai, M.; Zhang, L.; Li, H.; Yan, F.; Xu, L. Q.; Tian, G.-B.

10.1101/2021.02.26.433140 — microbiology — Posted on 2021-03-01

4947 Genome-wide chromatin accessibility analyses provide a map for enhancing optic nerve regeneration

Pita-Thomas, W.; Mangetti Goncalves, T.; Zhao, G.; Cavalli, V.

10.1101/2021.02.25.432980 — neuroscience — Posted on 2021-03-01

4948 A novel function for Rab proteins during maturation of secretory granules

Neuman, S. D.; Lee, A. R.; Selegue, J. E.; Cavanagh, A. T.; Bashirullah, A.

10.1101/2021.03.01.433309 — cell biology — Posted on 2021-03-01

4949 Hierarchical progressive learning of cell identities in single-cell data

Michielsen, L.; Reinders, M.; Mahfouz, A.

10.1101/2020.03.27.010124 — bioinformatics — Posted on 2021-03-01

4950 Comparative Analysis of common alignment tools for single cell RNA sequencing

Bruening, R. S.; Tombor, L.; Schulz, M. H.; Dimmeler, S.; John, D.

10.1101/2021.02.15.430948 — bioinformatics — Posted on 2021-03-01

4951 Reinstatement of cortical outcome representations during higher-order learning

Luettgau, L.; Porcu, E.; Tempelmann, C.; Jocham, G.

10.1101/2020.05.28.121558 — neuroscience — Posted on 2021-03-01

4952 Multimodal Analysis for Human ex vivo Studies Shows Extensive Molecular Changes from Delays in Blood Processing

Savage, A. K.; Gutschow, M. V.; Chiang, T.; Henderson, K.; Green, R.; Chaudhari, M.; Swanson, E.; Heubeck, A. T.; Kondza, N.; Burley, K. C.; Genge, P. C.; Lord, C.; Smith, T.; Thomson, Z.; Beaubien, A.; Goldy, J.; Bolouri, H.; Buckner, J. H.; Meijer, P.; Coffey, E. M.; Skene, P. J.; Torgerson, T. R.; Li, X.-j.; Bumol, T. F.

10.1101/2020.10.18.344663 — immunology — Posted on 2021-03-01

4953 Large-scale societal dynamics are reflected in human mood and brain

Lebedev, A. V.; Abe, C.; Acar, K.; Deco, G.; Kringelbach, M. L.; Ingvar, M.; Petrovic, P.

10.1101/2020.10.07.329201 — neuroscience — Posted on 2021-03-01

4954 Persister state-directed transitioning and vulnerability in melanoma

Chauvistre, H.; Shannan, B.; Daignault, S. M.; Ju, R. J.; Picard, D.; Egetemaier, S.; Varaljai, R.; Sechi, A.; Kaschani, F.; Keminer, O.; Stehbens, S. J.; Liu, Q.; Yin, X.; Jeyakumar, K.; Vogel, F. C. E.; Krepler, C.; Rebecca, V. W.; Kubat, L.; Lueong, S. S.; Forster, J.; Horn, S.; Remke, M.; Ehrmann, M.; Paschen, A.; Becker, J. C.; Helfrich, I.; Rauh, D.; Kaiser, M.; Gul, S.; Herlyn, M.; Rodriguez-Lopez, J. N.; Haass, N. K.; Schadendorf, D.; Roesch, A.

10.1101/2020.04.01.999847 — cancer biology — Posted on 2021-03-01

4955 The structural connectome constrains fast brain dynamics

Sorrentino, P.; Seguin, C.; Rucco, R.; Liparoti, M.; Troisi Lopez, E.; Bonavita, S.; Quarantelli, M.; Sorrentino, G.; Jirsa, V.; Zalesky, A.

10.1101/2020.11.25.393017 — neuroscience — Posted on 2021-03-01

Archive, 2021-03