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Archive, 2021-12

3 Bioprinting the Tumor Microenvironment with an Upgraded Consumer Stereolithographic 3D Printer
Breideband, L.; Wächtershäuser, K. N.; Hafa, L.; Wieland, K.; Frangakis, A.; Stelzer, E. H. K.; Pampaloni, F.
10.1101/2021.12.30.474546 — bioengineering — Posted on 2021-12-31
6 Endosomal structure and APP biology are not altered in preclinical cellular models of Down syndrome
Cannavo, C.; Cleverley, K.; Maduro, C.; Mumford, P.; Moulding, D.; Fisher, E.; Wiseman, F. K.
10.1101/2021.12.30.474570 — neuroscience — Posted on 2021-12-30
9 Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement
McCallum, M.; Czudnochowski, N.; Rosen, L. E.; Zepeda, S. K.; Bowen, J. E.; Dillen, J. R.; Powell, A.; Croll, T.; Nix, J.; Virgin, H. W.; Corti, D.; Snell, G.; Veesler, D.
10.1101/2021.12.28.474380 — biochemistry — Posted on 2021-12-31
10 Work and oxygen consumption of isolated right ventricular papillary muscle in experimental pulmonary hypertension
van der Laarse, W. J.; Bogaards, S. J. P.; Schalij, I.; Vonk Noordegraaf, A.; Vaz, F. M.; van Groen, D.
10.1101/2021.12.30.474521 — physiology — Posted on 2021-12-30
12 High density single-unit human cortical recordings using the Neuropixels probe
Chung, J. E.; Sellers, K. K.; Leonard, M. K.; Gwilliams, L.; Xu, D.; Dougherty, M.; Kharazia, V.; Welkenhuysen, M.; Dutta, B.; Chang, E. F.
10.1101/2021.12.29.474489 — neuroscience — Posted on 2021-12-30
13 Controlling pallidal oscillations in real-time in Parkinson's disease using evoked interference deep brain stimulation (eiDBS): proof of concept in the human
Escobar Sanabria, D.; Aman, J. E.; Zapata Amaya, V.; Johnson, L. A.; Farooqi, H.; Wang, J.; Hill, M.; Patriat, R.; Sovell-Brown, K.; Molnar, G. F.; Darrow, D.; McGovern, R.; Cooper, S. E.; Harel, N.; MacKinnon, C. D.; Park, M. C.; Vitek, J. L.
10.1101/2021.05.22.445251 — neuroscience — Posted on 2021-12-30
15 Impact of circadian time of dosing on cardiac-autonomous effects of glucocorticoids
Wintzinger, M.; Panta, M.; Miz, K.; Pragasam, A. D. P.; Sargent, M.; Peek, C.; Bass, J.; Molkentin, J.; Quattrocelli, M.
10.1101/2021.12.30.474468 — physiology — Posted on 2021-12-30
16 Tissue Registration and Exploration User Interfaces in support of a Human Reference Atlas
Borner, K.; Bueckle, A.; Herr, B. W.; Cross, L. E.; Quardokus, E. M.; Record, E. G.; Ju, Y.; Silverstein, J. C.; Browne, K.; Jain, S.; Wasserfall, C. H.; Jorgensen, M. L.; Spraggins, J. M.; Patterson, N. H.; Weber, G. M.
10.1101/2021.12.30.474265 — bioinformatics — Posted on 2021-12-30
17 A nanopore interface for high bandwidth DNA computing
Zhang, K.; Chen, Y.-J.; Doroschak, K.; Strauss, K.; Ceze, L.; Seelig, G.; Nivala, J.
10.1101/2021.12.30.474555 — bioengineering — Posted on 2021-12-30
18 A Musculoskeletal Model of the Hand and Wrist Capable of Simulating Functional Tasks
McFarland, D. C.; Binder-Markey, B. I.; Nichols, J. A.; Wohlman, S. J.; de Bruin, M.; Murray, W. M.
10.1101/2021.12.28.474357 — bioengineering — Posted on 2021-12-30
20 An Empirical Bayes Approach to Estimating Dynamic Models of Co-regulated Gene Expression
Venkatraman, S.; Basu, S.; Clark, A. G.; Delbare, S. Y. N.; Lee, M. H.; Wells, M. T.
10.1101/2021.07.08.451684 — genomics — Posted on 2021-12-30
27 Map-independent representation of an aggression-promoting social cue in the main olfactory pathway
Cichy, A.; Dewan, A.; Zhang, J.; Kaye, S.; Teng, T.; Blanchard, K.; Feinstein, P.; Bozza, T.
10.1101/2021.12.30.474554 — neuroscience — Posted on 2021-12-30
35 Bioprinting the Tumor Microenvironment with an Upgraded Consumer Stereolithographic 3D Printer
Breideband, L.; Wächtershäuser, K. N.; Hafa, L.; Wieland, K.; Frangakis, A.; Stelzer, E. H. K.; Pampaloni, F.
10.1101/2021.12.30.474546 — bioengineering — Posted on 2021-12-30
37 TXNRD3 supports male fertility via the redox control of spermatogenesis
Dou, Q.; Turanov, A. A.; Mariotti, M.; Hwang, J. Y.; Wang, H.; Lee, S.-G.; Paulo, J. A.; Yim, S. H.; Gygi, S.; Chung, J.-J.; Gladyshev, V. N.
10.1101/2021.12.29.474493 — biochemistry — Posted on 2021-12-30
39 Engineered chimeras unveil swappable modular features of fatty acid and polyketide synthase acyl carrier proteins
Cho, Y. I.; Armstrong, C. L.; Sulpizio, A.; Acheampong, K. K.; Banks, K. N.; Bardhan, O.; Churchill, S. J.; Connolly-Sporing, A. E.; Crawford, C. E. W.; Cruz Parrilla, P. L.; Curtis, S. M.; De La Ossa, L. M.; Epstein, S. C.; Farrehi, C. J.; Hamrick, G. S.; Hillegas, W. J.; Kang, A.; Laxton, O. C.; Ling, J.; Matsumura, S. M.; Marino, V. M.; Mukhtar, S. H.; Shah, N. J.; Londergan, C. H.; Daly, C. A.; Kokona, B.; Charkoudian, L. K.
10.1101/2021.12.30.471467 — biochemistry — Posted on 2021-12-30
40 Substrate Specificity for Human Histidine Methyltransferase SETD3
Hintzen, J.; Ma, H.; Deng, H.; Witecka, A.; Andersen, S. B.; Drozak, J.; Guo, H.; Qian, P.; Li, H.; Mecinovic, J.
10.1101/2021.12.30.474520 — biochemistry — Posted on 2021-12-30
43 iTRVZ: liquid nano-platform for signal integration on the plasma membrane
Tsunoyama, T. A.; Hoffmann, C.; Tang, B.; Hirosawa, K. M.; Nemoto, Y. L.; Kasai, R. S.; Fujiwara, T.; Suzuki, K. G.; Milovanovic, D.; Kusumi, A.
10.1101/2021.12.30.474523 — cell biology — Posted on 2021-12-30
44 Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function
Ravichandran, M.; Rafalski, D.; Ortega-Recalde, O.; Davies, C. I.; Glanfield, C. R.; Kotter, A.; Misztal, K.; Wang, A. H.; Wojciechowski, M.; Razew, M.; Mayyas, I. M.; Kardailsky, O.; Schwarz, U.; Zembrzycki, K.; Morison, I. M.; Helm, M.; Weichenhan, D.; Jurkowska, R. Z.; Krueger, F.; Plass, C.; Zacharias, M.; Hore, T. A.; Bochtler, M.; Jurkowski, T. P.
10.1101/2021.12.29.474486 — molecular biology — Posted on 2021-12-30
46 Kinetics Of Interferon-{lambda} And Receptor Expression In Response To In Vitro Respiratory Viral Infection
Lozhkov, A.; Yolshin, N.; Baranovskaya, I.; Plotnikova, M.; Sergeeva, M.; Gyulikhandanova, N.; Klotchenko, S.; Vasin, A.
10.1101/2021.12.30.474514 — immunology — Posted on 2021-12-30
50 Depletion of CD206+ Tumour Macrophages via a Peptide-Targeted Star-Shaped Polyglutamate Inhibits Tumourigenesis and Metastatic Dissemination in Mouse Breast Cancer Models
Lepland, A.; Malfanti, A.; Haljasorg, U.; Asciutto, E.; Pickholz, M.; Bringas, M.; Dordevic, S.; Salumae, L.; Peterson, P.; Teesalu, T.; Vicent, M. J.; Scodeller, P.
10.1101/2021.12.29.474487 — cancer biology — Posted on 2021-12-30
53 Single-nuclei isoform RNA sequencing reveals combination patterns of transcript elements across human brain cell types
Hardwick, S. A.; Hu, W.; Joglekar, A.; Fan, L.; Collier, P. G.; Foord, C.; Balacco, J.; Belchikov, N.; Jarroux, J.; Prjibelski, A. D.; Mikheenko, A.; Luo, W.; Milner, T. A.; Ndhlovu, L.; Trojanowski, J. Q.; Lee, V. M.; Fedrigo, O.; Tombacz, D.; Ross, M. E.; Jarvis, E.; Boldogkoi, Z.; Gan, L.; Tilgner, H. U.
10.1101/2021.12.29.474385 — genomics — Posted on 2021-12-30
54 Ablation of the FACIT collagen XII disturbs musculoskeletal ECM organization and causes patella dislocation and myopathy
Zhu, M.; Metzen, F.; Betz, J.; Hopkinson, M.; Pitsillides, A. A.; Paulsson, M.; Koch, M.; Brachvogel, B.; Izu, Y.; Schreiber, G.; Imhof, T.; Birk, D. E.; Heilig, J.; Niehoff, A.; Altmueller, J.
10.1101/2021.12.29.474475 — genetics — Posted on 2021-12-30
58 Nipah virus detection at bat roosts following spillover events in Bangladesh, 2012-2019
McKee, C. D.; Islam, A.; Rahman, M. Z.; Khan, S. U.; Rahman, M.; Satter, S. M.; Islam, A.; Yinda, C. K.; Epstein, J. H.; Daszak, P.; Munster, V. J.; Hudson, P. J.; Plowright, R. K.; Luby, S. P.; Gurley, E. S.
10.1101/2021.12.29.474445 — ecology — Posted on 2021-12-30
59 Nerve-mediated amputation-induced stem cell activation primes distant appendages for future regeneration events in axolotl
Payzin-Dogru, D.; Wilson, S. E.; Blair, S. J.; Erdogan, B.; Hossain, S.; Cammarata, L. V.; Velazquez Matos, J. C.; Wong, A. Y.; Losner, J.; Min, S.; Singer, H.; Whited, J. L.
10.1101/2021.12.29.474455 — developmental biology — Posted on 2021-12-30
60 A NEUROGENIC GENE EXPRESSION SIGNATURE SUPPORTS HUMAN THERMOGENIC ADIPOSE TISSUE DEVELOPMENT IN VIVO.
Solivan-Rivera, J.; Yang Loureiro, Z.; DeSouza, T.; Desai, A.; Yang, Q.; Rojas-Rodriguez, R.; Skritakis, P.; Joyce, S.; Zhong, D.; Nguyen, T.; Corvera, S.
10.1101/2021.12.29.474474 — developmental biology — Posted on 2021-12-30
64 SARS-CoV-2 diverges from other betacoronaviruses in only partially activating the IRE1α/XBP1 ER stress pathway in human lung-derived cells
Nguyen, L. C.; Renner, D. M.; Silva, D.; Yang, D.; Medina, K. M.; Nicolaescu, V.; Gula, H.; Drayman, N.; Valdespino, A.; Mohamed, A.; Dann, C.; Wannemo, K.; Robinson-Mailman, L.; Gonzalez, A.; Stock, L.; Cao, M.; Qiao, Z.; Moellering, R. E.; Tay, S.; Randall, G.; Beers, M. F.; Rosner, M. R.; Oakes, S. A.; Weiss, S. R.
10.1101/2021.12.30.474519 — microbiology — Posted on 2021-12-30
65 Subgenomic SARS-CoV-2 replicon and reporter replicon cell lines enable ultrahigh throughput antiviral screening and mechanistic studies with antivirals, viral mutations or host factors that affect COVID-19 replication
Lan, S.; Tedbury, P. R.; Ong, Y. T.; Shah, R.; Slack, R. L.; Cilento, M. E.; Zhang, H.; Du, H.; Lulkin, N.; Le, U. Q.; Kirby, K. A.; Melcak, I.; Cantara, W. A.; Boggs, E. A.; Sarafianos, S. G.
10.1101/2021.12.29.474471 — microbiology — Posted on 2021-12-30
66 Molecular probes of spike ectodomain and its subdomains for SARS-CoV-2 variants, Alpha through Omicron
Teng, I.-T.; Nazzari, A. F.; Choe, M.; Liu, T.; Oliveira de Souza, M.; Petrova, Y.; Tsybovsky, Y.; Wang, S.; Zhang, B.; Artamonov, M.; Madan, B.; Huang, A.; Lopez Acevedo, S. N.; Pan, X.; Ruckwardt, T. J.; DeKosky, B. J.; Mascola, J. R.; Misasi, J.; Sullivan, N.; Zhou, T.; Kwong, P. D.
10.1101/2021.12.29.474491 — immunology — Posted on 2021-12-30
67 Preserved T cell reactivity to the SARS-CoV-2 Omicron variant indicates continued protection in vaccinated individuals.
De Marco, L.; D'Orso, S.; Pirronello, M.; Verdiani, A.; Termine, A.; Fabrizio, C.; Capone, A.; Sabatini, A.; Guerrera, G.; Placido, R.; Sambucci, M.; Angelini, D. F.; Giannessi, F.; Picozza, M.; Caltagirone, C.; Salvia, A.; Volpe, E.; Balice, M. P.; Rossini, A.; Rotzschke, O.; Giardina, E.; Battistini, L.; Borsellino, G.
10.1101/2021.12.30.474453 — immunology — Posted on 2021-12-30
73 Unsupervised genome-wide cluster analysis: nucleotide sequences of the omicron variant of SARS-CoV-2 are similar to sequences from early 2020
Hahn, G.; Lee, S.; Prokopenko, D.; Novak, T.; Hecker, J.; Khurana, S.; Baden, L. R.; Randolph, A. G.; Weiss, S. T.; Lange, C.
10.1101/2021.12.29.474469 — bioinformatics — Posted on 2021-12-30
74 The transmission of African Animal Trypanosomiasis (Nagana) in two districts in the forest zone of Ghana
Tweneboah, A.; Rosenau, J.; Agyapong, A. K.; Addison, T. K.; Mahamat, I. A. M.; Weber, J. S.; Kelm, S.; Badu, K.
10.1101/2021.08.11.455898 — evolutionary biology — Posted on 2021-12-30
75 Viral population genomics reveals host and infectivity impact on SARS-CoV-2 adaptive landscape
Gayvert, K.; Copin, R.; McKay, S.; Setliff, I.; Lim, W. K.; Baum, A.; Kyratsous, C. A.; Atwal, G. S.
10.1101/2021.12.30.474516 — evolutionary biology — Posted on 2021-12-30
76 Increased resistance of SARS-CoV-2 Omicron Variant to Neutralization by Vaccine-Elicited and Therapeutic Antibodies
Tada, T.; Zhou, H.; Dcosta, B. M.; Samanovic, M. I.; Chivukula, V.; Herati, R.; Hubbard, S. R.; Mulligan, M. J.; Landau, N. R.
10.1101/2021.12.28.474369 — immunology — Posted on 2021-12-30
77 Pipeline for retrieval of COVID-19 immune signatures
Newton, A. J. H.; Chartash, D.; Kleinstein, S. H.; McDougal, R. A.
10.1101/2021.12.29.474353 — immunology — Posted on 2021-12-30
78 Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody
Li, C.; Zhan, W.; Yang, Z.; Tu, C.; Zhu, Y.; Song, W.; Huang, K.; Gu, X.; Kong, Y.; Zhang, X.; Zhang, M.; Zhang, Y.; Xie, Y.; Deng, Q.; Chen, Z.; Lu, L.; Jiang, S.; Sun, L.; Wu, Y.; Ying, T.
10.1101/2021.12.30.474535 — immunology — Posted on 2021-12-30
79 Synaptic integration of subquantal neurotransmission by co-localized G protein coupled receptors in presynaptic terminals
Church, E.; Hamid, E.; Zurawski, Z. P.; Potcoava, M.; Flores-Barrera, E.; Caballero, A.; Tseng, K. Y.; Alford, S.
10.1101/2020.11.12.362491 — neuroscience — Posted on 2021-12-30
80 VRK1 is required in VRK2-methylated cancers of the nervous system
So, J.; Mabe, N.; Englinger, B.; Trissal, M.; Jeong, D.; Panditharatna, E. A.; Marques, J. G.; Justin, H.; Kwon, J.; Moyer, S. M.; Shim, B.; Mayhew, D. L.; Stegmaier, K.; Filbin, M. G.; Hahn, W. C.
10.1101/2021.12.28.474386 — cancer biology — Posted on 2021-12-30
81 Multi-Wavelength Analytical Ultracentrifugation of Biopolymer Mixtures and Interactions
Henrickson, A.; Gorbet, G. E.; Savelyev, A.; Kim, M.; Schultz, S. K.; Ding, X.; Hargreaves, J.; Gradinaru, V.; Kothe, U.; Demeler, B.
10.1101/2021.12.29.474408 — biophysics — Posted on 2021-12-30
83 Structural and functional characterizations of altered infectivity and immune evasion of SARS-CoV-2 Omicron variant
Cui, Z.; Liu, P.; Wang, N.; Wang, L.; Fan, K.; Zhu, Q.; Wang, K.; Chen, R.; Feng, R.; Jia, Z.; Yang, M.; Zhu, B.; Fu, W.; Chu, T.; Feng, L.; Wang, Y.; Pei, X.; Yang, P.; Xie, X. S.; Cao, L.; Cao, Y. R.; Wang, X.
10.1101/2021.12.29.474402 — biophysics — Posted on 2021-12-30
89 Microtubule plus-end regulation by centriolar cap proteins
Ogunmolu, F. E.; Moradi, S.; Volkov, V. A.; van Hoorn, C.; Wu, J.; Andrea, N.; Hua, S.; Jiang, K.; Vakonakis, I. A.; Potocnjak, M.; Herzog, F.; Gigant, B.; Gudimchuk, N.; Stecker, K. E.; Dogterom, M.; Steinmetz, M. O.; Akhmanova, A.
10.1101/2021.12.29.474442 — cell biology — Posted on 2021-12-30
90 Thermal sensitivity and seasonal change in the gut microbiome of a desert ant, Cephalotes rohweri
McMunn, M. S.; Hudson, A. I.; Zemenick, A.; Egerer, M.; Philpott, S. M.; Vannette, R. L.
10.1101/2021.12.28.474384 — microbiology — Posted on 2021-12-30
91 Natural history of nonhuman primates after conjunctival exposure to Ebola virus
Cross, R. W.; Prasad, A. N.; Woolsey, C.; Agans, K. N.; Borisevich, V.; Dobias, N. S.; Comer, J. E.; Deer, D. J.; Geisbert, J. B.; Rasmussen, A.; Lipkin, W. I.; Fenton, K. A.; Geisbert, T. W.
10.1101/2021.12.29.474476 — microbiology — Posted on 2021-12-30
94 Design of Epitope Based Peptide Vaccine against Brucella Abortus OmpW Family Protein using Immunoinformatics
Elhag, M.; Abdelmoneim, A. H.; Sati, A. O.; Mohammed Saadaldin, M.; Ahmad, N. M.; Hassan, M. A.
10.1101/2021.12.27.474190 — bioinformatics — Posted on 2021-12-30
99 SoyFGB v2.0: a unique access to variations of Chinese Soybean Gene Bank (CNSGB) germplasm
Zheng, T.; Li, Y.; Li, Y.; Zhang, S.; Wang, C.; Zhang, F.; Zhang, L.; Wu, X.; Tian, Y.; Jiang, S.; Xu, J.; Qiu, L.
10.1101/2021.12.28.474253 — genomics — Posted on 2021-12-30
101 Perception and propagation of activity through the cortical hierarchy is determined by neural variability
Rowland, J. M.; van der Plas, T. L.; Loidolt, M.; Lees, R. M.; Keeling, J.; Dehning, J.; Akam, T.; Priesemann, V.; Packer, A. M.
10.1101/2021.12.28.474343 — neuroscience — Posted on 2021-12-30
103 Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody: mechanisms for the high infectivity, immune evasion and antibody drug discovery
Yin, W.; Xu, Y.; Xu, P.; Cao, X.; Wu, C.; Gu, C.; He, X.; Wang, X.; Huang, S.; Yuan, Q.; Wu, K.; Hu, W.; Huang, Z.; Liu, J.; Wang, Z.; Jia, F.; Xia, K.; Liu, P.; Wang, X.; Song, B.; Zheng, J.; Jiang, H.; Cheng, X.; Jiang, Y.; Deng, S.-J.; Xu, H. E.
10.1101/2021.12.27.474273 — biophysics — Posted on 2021-12-30
104 Structural Evolution of the Ancient Enzyme, Dissimilatory Sulfite Reductase
Colman, D. R.; Labesse, G.; Swapna, G. V. T.; Stefanakis, J.; Montelione, G. T.; Boyd, E. S.; Royer, C. A.
10.1101/2021.12.28.474277 — biophysics — Posted on 2021-12-30
106 Polygenic routes lead to parallel altitudinal adaptation in Heliosperma pusillum (Caryophyllaceae)
Szukala, A.; Lovegrove-Walsh, J.; Luqman, H.; Fior, S.; Wolfe, T. M.; Frajman, B.; Schoenswetter, P.; Paun, O.
10.1101/2021.07.05.451094 — evolutionary biology — Posted on 2021-12-30
107 Scrutiny of human lung infection by SARS-CoV-2 and associated human immune responses in humanized mice
Sun, R.; Zhao, Z.; Fu, C.; Wang, Y.; Guo, Z.; Zhang, C.; Liu, L.; Zhang, C.; Shu, C.; He, J.; Hua, S.; Gao, Y.; Hu, Z.
10.1101/2021.11.05.466755 — immunology — Posted on 2021-12-30
109 A versatile active learning workflow for optimization of genetic and metabolic networks
Pandi, A.; Diehl, C.; Yazdizadeh Kharrazi, A.; Faure, L.; Scholz, S. A.; Nattermann, M.; Adam, D.; Chapin, N.; Foroughijabbari, Y.; Moritz, C.; Paczia, N.; Socorro Cortina, N.; Faulon, J.-L.; Erb, T. J.
10.1101/2021.12.28.474323 — synthetic biology — Posted on 2021-12-30
110 Pathological characteristics of pulmonary toxicity in F344 rats exposed by inhalation to cross-linked water-soluble acrylic acid polymers
Yamano, S.; Takeda, T.; Goto, Y.; Hirai, S.; Furukawa, Y.; Kikuchi, Y.; Misumi, K.; Suzuki, M.; Takanobu, K.; Senoh, H.; Saito, M.; Kondo, H.; Kobashi, Y.; Okamoto, K.; Kishimoto, T.; Umeda, Y.
10.1101/2021.11.13.468475 — pharmacology and toxicology — Posted on 2021-12-30
113 SARS-CoV-2 Omicron-B.1.1.529 Variant leads to less severe disease than Pango B and Delta variants strains in a mouse model of severe COVID-19
Bentley, E. G.; Kirby, A.; Sharma, P.; Kipar, A.; Mega, D. F.; Bramwell, C.; Penrice-Randal, R.; Prince, T.; Brown, J. C.; Zhou, J.; Screaton, G. R.; Barclay, W. S.; Owen, A.; Hiscox, J. A.; Stewart, J. P.
10.1101/2021.12.26.474085 — microbiology — Posted on 2021-12-30
118 Dose-response relationship of pulmonary disorders by inhalation exposure to cross-linked water-soluble acrylic acid polymers in F344 rats
Takeda, T.; Yamano, S.; Goto, Y.; Hirai, S.; Furukawa, Y.; Kikuchi, Y.; Misumi, K.; Suzuki, M.; Takanobu, K.; Senoh, H.; Saito, M.; Kondo, H.; Kobashi, Y.; Okamoto, K.; Kishimoto, T.; Umeda, Y.
10.1101/2021.12.26.474221 — pharmacology and toxicology — Posted on 2021-12-30
122 Homologous or Heterologous Booster of Inactivated Vaccine Reduces SARS-CoV-2 Omicron Variant Escape from Neutralizing Antibodies
Wang, X.; Zhao, X.; Song, J.; Wu, J.; Zhu, Y.; Li, M.; Cui, Y.; Chen, Y.; Yang, L.; Liu, J.; Zhu, H.; Jiang, S.; Wang, P.
10.1101/2021.12.24.474138 — microbiology — Posted on 2021-12-30
123 Species-specific mitochondria dynamics and metabolism regulate the timing of neuronal development
Iwata, R.; Casimir, P.; Erkol, E.; Boubakar, L.; Planque, M.; Ditkowska, M.; Vints, K.; Poovathingal, S.; Gaspariunaite, V.; Bird, M.; Corthout, N.; Vermeersch, P.; Davie, K.; Gounko, N. V.; Aerts, S.; Ghesquiere, B.; Fendt, S.-M.; Vanderhaeghen, P.
10.1101/2021.12.27.474246 — neuroscience — Posted on 2021-12-30
125 Diversity of microglial transcriptional responses during opioid exposure and neuropathic pain
Sypek, E. I.; Collins, H. Y.; McCallum, W. M.; Bourdillon, A. T.; Bohlen, C. J.; Scherrer, G.
10.1101/2021.12.29.473853 — neuroscience — Posted on 2021-12-29
126 Landscape of human spinal cord cell type diversity at midgestation
Andersen, J.; Thom, N.; Shadrach, J. L.; Chen, X.; Amin, N. D.; Yoon, S.-J.; Greenleaf, W. J.; Muller, F.; Pasca, A. M.; Kaltschmidt, J. A.; Pasca, S. P.
10.1101/2021.12.29.473693 — neuroscience — Posted on 2021-12-29
129 Clathrin-mediated Endocytosis Facilitates Internalization of Magnaporthe oryzae Effectors into Rice Cells
Oliveira-Garcia, E.; Tamang, T. M.; Park, J.-E.; Dalby, M.; Martin-Urdiroz, M.; Rodriguez Herrero, C.; Hong Vu, A.; Park, S.; Talbot, N. J.; Valent, B.
10.1101/2021.12.28.474284 — plant biology — Posted on 2021-12-29
130 A spatial stochastic model reveals the role of supercoiling in transcription regulation
Geng, Y.; Bohrer, C. H.; Yehya, N.; Hendrix, H.; Shachaf, L.; Liu, J.; Xiao, J.; Roberts, E.
10.1101/2021.12.29.474406 — biophysics — Posted on 2021-12-29
132 Screening of Chimeric GAA Variants in a Preclinical Study of Pompe Disease Results in Candidate Vector for Hematopoietic Stem Cell Gene Therapy
Dogan, Y.; Barese, C. N.; Schindler, J. W.; Yoon, J. K.; Unnisa, Z.; Guda, S.; Jacobs, M. E.; Oborski, C.; Clarke, D. L.; Schambach, A.; Pfeifer, R.; Harper, C.; Mason, C.; van Til, N. P.
10.1101/2021.12.28.474352 — bioengineering — Posted on 2021-12-29
135 FastCAT accelerates absolute quantification of proteins by using multiple short non-purified chimeric standards
Rzagalinski, I.; Bogdanova, A.; Raghuraman, B. K.; Geertsma, E. R.; Hersemann, L.; Ziemssen, T.; Shevchenko, A.
10.1101/2021.12.28.474379 — biochemistry — Posted on 2021-12-29
136 Regulation of Kidney Mitochondrial Function by Caloric Restriction
Serna, J. D.; Amaral, A. G.; Caldeira da Silva, C. C.; Bonassa, A. C.; Menezes, S. L.; Kowaltowski, A. J.
10.1101/2021.12.29.474441 — biochemistry — Posted on 2021-12-29
141 Single Nuclei Transcriptome Reveals Perturbed Brain Vascular Molecules in Alzheimer's Disease
Is, O.; Wang, X.; Patel, T. A.; Quicksall, Z. S.; Heckman, M. G.; White, L. J.; Lewis-Tuffin, L. J.; Deniz, K.; Tutor-New, F. Q.; Carnwath, T. P.; Min, Y.; Oatman, S. R.; Reddy, J. S.; Carrasquillo, M. M.; Nguyen, T. T.; Ho, C. C. G.; Malphrus, K. G.; Nho, K.; Murray, M. E.; Dickson, D. W.; Saykin, A. J.; Allen, M.; Ertekin-Taner, N.
10.1101/2021.12.28.474255 — neuroscience — Posted on 2021-12-29
142 The GluN2A subunit of the NMDA receptor modulates the rate of functional maturation in parvalbumin-positive interneurons
Camp, C. R.; Shapiro, L.; Vlachos, A.; Perszyk, R. E.; Shariatzadeh, N.; White, J.; Sanchez, R.; Koh, S.; Escayg, A.; Yuan, H.; McBain, C. J.; Pelkey, K. A.; Traynelis, S. F.
10.1101/2021.12.29.474447 — neuroscience — Posted on 2021-12-29
143 Copper imbalance linked to oxidative stress and cell death during Zika virus infection in human astrocytes
Puig-Pijuan, T.; R. Q. Souza, L.; da S. G. Pedrosa, C.; M. Higa, L.; Monteiro, F. L.; Tanuri, A.; H. F. Valverde, R.; Einicker-Lamas, M.; Kastrup Rehen, S.
10.1101/2021.12.29.474370 — neuroscience — Posted on 2021-12-29
145 An automated microfluidic platform integrating functional vascularized organoids-on-chip
Quintard, C.; Jonsson, G.; Laporte, C.; Bissardon, C.; Pitaval, A.; Werschler, N.; Leopoldi, A.; Hagelkrüys, A.; Blandin, P.; Achard, J.-L.; Navarro, F.; Fouillet, Y.; Penninger, J. M.; Gidrol, X.
10.1101/2021.12.29.474327 — bioengineering — Posted on 2021-12-29
146 Genome assembly, transcriptome and SNP database for chum salmon (Oncorhynchus keta)
Rondeau, E. B.; Christensen, K. A.; Sakhrani, D.; Biagi, C. A.; Wetklo, M.; Johnson, H. A.; Despins, C. A.; Leggatt, R. A.; Minkley, D. R.; Withler, R. E.; Beacham, T. D.; Koop, B. F.; Devlin, R. H.
10.1101/2021.12.27.474290 — genomics — Posted on 2021-12-29
149 AtERF60 negatively regulates ABR1 to modulate salt, drought, and basal resistance in Arabidopsis
Jeena, G. S.; Phukan, U. J.; Singh, N.; Joshi, A.; Pandey, A.; Sharma, Y.; Tripathi, V.; Shukla, R.
10.1101/2021.12.29.474403 — plant biology — Posted on 2021-12-29
151 Deciphering sex-specific miRNAs as heat-recorders in zebrafish
van Gelderen, T.; Montfort, J.; Alvarez-Dios, J. A.; Thermes, V.; Piferrer, F.; Bobe, J.; Ribas, L.
10.1101/2021.12.29.474410 — genomics — Posted on 2021-12-29
156 Dynamic Expedition of Leading Mutations in SARS-CoV-2 Spike Glycoproteins
He, Z.; Hasan, M.; Jia, M.; Natarajan, K.; Yap, S. Q.; Zhou, F.; Su, H.; Zhu, K.; Su, H.
10.1101/2021.12.29.474427 — evolutionary biology — Posted on 2021-12-29
157 Herbivorous fish of Sinai marine protected areas (Gulf of Aqaba): Structure baseline for potential thermal stress impact management
El-Haddad, K. M.; Ali, A.-H. A.; Abdel-Rahman, M. S.; Mohammed, S. Z.; Abdel-Gawad, F. K.; Guerriero, G.; Temraz, T. A.
10.1101/2021.09.17.460804 — ecology — Posted on 2021-12-29
158 A single cell transcriptional roadmap for human pacemaker cell differentiation
Wiesinger, A.; Li, J.; Fokkert, L. J.; Bakker, P.; Verkerk, A. O.; Christoffels, V. M.; Boink, G. J. J.; Devalla, H. D.
10.1101/2021.12.28.474383 — developmental biology — Posted on 2021-12-29
160 A transient apical extracellular matrix relays cytoskeletal patterns to shape permanent acellular ridges on the surface of adult C. elegans
Katz, S. S.; Barker, T. J.; Maul-Newby, H. M.; Sparacio, A. P.; Nguyen, K. C. Q.; Maybrun, C. L.; Belfi, A.; Cohen, J. D.; Hall, D. H.; Sundaram, M. V.; Frand, A. R.
10.1101/2021.12.28.474392 — developmental biology — Posted on 2021-12-29
163 mRNA-1273 and Ad26.COV2.S vaccines protect against the B.1.621 variant of SARS-CoV-2
Darling, T. L.; Ying, B.; Whitener, B.; VanBlargan, L.; Bricker, T. L.; Liang, C.-Y.; Joshi, A.; Bamunuarachchi, G.; Seehra, K.; Schmitz, A.; Halfmann, P.; Kawaoka, Y.; Elbashir, S.; Edwards, D. K.; Thackray, L.; Diamond, M.; Boon, A.
10.1101/2021.12.29.474432 — microbiology — Posted on 2021-12-29
164 A Novel CRISPR-Engineered, Stem Cell-Derived Cellular Vaccine
Chakraborty, K.; Chandrashekar, A.; Sidaway, A.; Latta, E.; Yu, J.; McMahan, K.; Manickam, C.; Kroll, K.; Mosher, M.; Reeves, R. K.; Gam, R.; Arthofer, E.; Choudhry, M.; Barouch, D. H.; Henley, T.
10.1101/2021.12.28.474336 — immunology — Posted on 2021-12-29
166 Qualifying a human Liver-Chip for predictive toxicology: Performance assessment and economic implications
Ewart, L.; Apostolou, A.; Briggs, S. A.; Carman, C. V.; Chaff, J. T.; Heng, A. R.; Jadalannagari, S.; Janardhanan, J.; Jang, K.-J.; Joshipura, S. R.; Kadam, M.; Kanellias, M.; Kujala, V. J.; Kulkarni, G.; Le, C. Y.; Lucchesi, C.; Manatakis, D.; Maniar, K. K.; Quinn, M. E.; Ravan, J. S.; Rizos, A. C.; Sauld, J. F. K.; Sliz, J.; Tien-Street, W.; Trinidad, D. R.; Velez, J.; Wendell, M.; Irrechukwu, O.; Mahalingaiah, P. K.; Ingber, D. E.; Levner, D.
10.1101/2021.12.14.472674 — pharmacology and toxicology — Posted on 2021-12-29
168 Wildlife is imperiled in peri-urban landscapes: threats to arboreal mammals
Chaves, O. M.; Souza, J. C.; Buss, G.; Hirano, Z. M. B.; Jardim, M. M. A.; Amaral, E.; Godoy, J. C.; Peruchi, A. R.; Michel, T.; Bicca-Marques, J. C.
10.1101/2021.10.30.466631 — ecology — Posted on 2021-12-29
169 Introducing a New Bond-Forming Activity in an Archaeal DNA Polymerase by Structure-Guided Enzyme Redesign
Aggarwal, T.; Hansen, W. A.; Hong, J.; Ganguly, A.; York, D. M.; Khare, S. D.; Izgu, E. C.
10.1101/2021.12.28.474375 — biochemistry — Posted on 2021-12-29
171 Precise measurement of nanoscopic septin ring structures in deep learning-assisted quantitative superresolution microscopy
Zehtabian, A.; Müller, P. M.; Goisser, M.; Obendorf, L.; Jänisch, L.; Hümpfer, N.; Rentsch, J.; Ewers, H.
10.1101/2021.12.28.474382 — cell biology — Posted on 2021-12-29
172 A high-throughput 3D bioprinted cancer cell migration and invasion model with versatile and broad biological applicability
Jung, M.; Skhinas, J.; Du, E. Y.; Tolentino, M. K.; Utama, R.; Engel, M.; Volkerling, A.; Sexton, A.; O'Mahony, A.; Ribeiro, J.; Gooding, J. J.; Kavallaris, M.
10.1101/2021.12.28.474387 — cell biology — Posted on 2021-12-29
173 Interleukin 4 controls the role of macrophages in pulmonary metastatic tumor cell seeding and growth
Rodriguez-Tirado, C. A.; Entenberg, D.; Li, J.; Qian, B.-Z.; Condeelis, J. S.; Pollard, J. W.
10.1101/2021.12.28.474388 — cancer biology — Posted on 2021-12-29
174 Biomechanical and biochemical assessment of YB-1 expression in melanoma cells
Cykowska, A. M.; Hofmann, U. K.; Tiwari, A.; Kosnopfel, C.; Riester, R.; Danalache, M.
10.1101/2021.12.29.474412 — cancer biology — Posted on 2021-12-29
176 Aberrant paracrine signalling for bone remodelling underlies the mutant histone-driven giant cell tumour of bone.
Cottone, L.; Ligammari, L.; Knowles, H. J.; Lee, H.-M.; Henderson, S.; Bianco, S.; Davies, C.; Strauss, S.; Amary, F.; Leite, A. P.; Tirabosco, R.; Haendler, K.; Schultze, J. L.; Herrero, J.; ODonnell, P.; Grigoriadis, A. E.; Salomoni, P.; Flanagan, A. M.
10.1101/2021.12.27.474195 — cancer biology — Posted on 2021-12-29
178 Designer Scaffolds for Interfacial Bioengineering
Hickey, R. J.; Leblanc Latour, M.; Harden, J. L.; Pelling, A.
10.1101/2020.11.06.371278 — biophysics — Posted on 2021-12-29
182 Dynamic behavior of cell-free mitochondrial DNA in human saliva
Trumpff, C.; Rausser, S.; Haahr, R.; Karan, K. R.; Gouspillou, G.; Puterman, E.; Kirschbaum, C.; Picard, M.
10.1101/2021.09.15.460321 — molecular biology — Posted on 2021-12-29
183 Alpha variant versus D614G strain in the Syrian hamster model
Cochin, M.; Luciani, L.; Touret, F.; Driouich, J. S.; Petit, P.-R.; Moureau, G.; Baronti, C.; Laprie, C.; Thirion, L.; Maes, P.; Boudewijns, R.; Neyts, J.; de Lamballerie, X.; Nougairede, A.
10.1101/2021.04.19.440435 — microbiology — Posted on 2021-12-29
184 Loss of Zfp335 triggers cGAS/STING-dependent apoptosis of post-β selection pre-T cells
Ratiu, J. J.; Barclay, W. E.; Wang, Q.; Mehta, N.; Harnois, M. J.; DiPalma, D.; Wellford, S.; Roy, S.; Contreras, A.; Wiest, D.; Zhuang, Y.
10.1101/2021.12.03.471158 — immunology — Posted on 2021-12-29
186 BrainGENIE: The Brain Gene Expression and Network Imputation Engine
Hess, J. L.; Quinn, T. P.; Zhang, C.; Hearn, G. C.; Chen, S.; Neuropsychiatric Consortium for Analysis and Sharing of Transcriptomes, ; Kong, S. W.; Cairns, M.; Tsuang, M.; Faraone, S. V.; Glatt, S. J.
10.1101/2020.10.27.356766 — bioinformatics — Posted on 2021-12-29
187 Production and characterization of virus-free, CRISPR-CAR T cells capable of inducing solid tumor regression
Mueller, K.; Piscopo, N.; Forsberg, M.; Saraspe, L.; Das, A.; Russell, B.; Smerchansky, M.; Shi, L.; Shankar, K.; Ali, A.; Lazzarotto, C.; Tsai, S.; Capitini, C. M.; Saha, K.
10.1101/2021.08.06.455489 — bioengineering — Posted on 2021-12-29
189 α-catenin links integrin adhesions to F-actin to regulate ECM mechanosensing and rigidity-dependence
Mukherjee, A.; Melamed, S.; Damouny-Khoury, H.; Amer, M.; Feld, L.; Nadjer-Boger, E.; Sheetz, M. P.; Wolfenson, H.
10.1101/2021.01.21.427565 — cell biology — Posted on 2021-12-29
191 Adult fibroblasts use aggresomes only in distinct cell-states
Morrow, C. S.; Arndt, Z. P.; Peng, B.; Zewdie, E. Y.; Benayoun, B. A.; Moore, D. L.
10.1101/2021.07.23.453501 — cell biology — Posted on 2021-12-29
193 Glucocorticoid signaling delays castration-induced regression in murine models of prostate cancer
Maolake, A.; Zhang, R.; Sha, K.; Singh, S.; Pan, C.; Xu, B.; Chatta, G.; Mastri, M.; Eng, K. H.; Krolewski, J. J.; Nastiuk, K. L.
10.1101/2021.10.11.463722 — cancer biology — Posted on 2021-12-29
195 Simple and cost-effective SNP genotyping method for discriminating subpopulations of the fish pathogen, Nocardia seriolae
Le, C. T.; Price, E. P.; Sarovich, D. S.; Nguyen, T. T. A.; Vu-Khac, H.; Kurtböke, I.; Knibb, W.; Chen, S.-C.; Katouli, M.
10.1101/2021.12.28.474260 — microbiology — Posted on 2021-12-29
196 In contrast to TH2-biased approaches, TH1 COVID-19 vaccines protect Syrian hamsters from severe disease in the absence of dexamethasone-treatable vaccine-associated enhanced respiratory pathology
Ebenig, A.; Muraleedharan, S.; Kazmierski, J.; Todt, D.; Auste, A.; Anzaghe, M.; Gömer, A.; Postmus, D.; Gogesch, P.; Niles, M.; Plesker, R.; Miskey, C.; Gellhorn Serra, M.; Breithaupt, A.; Hörner, C.; Kruip, C.; Ehmann, R.; Ivics, Z.; Waibler, Z.; Pfaender, S.; Wyler, E.; Landthaler, M.; Kupke, A.; Nouailles, G.; GOFFINET, C.; Brown, R. J. P.; Mühlebach, M. D.
10.1101/2021.12.28.474359 — immunology — Posted on 2021-12-28
198 Dendritic integration of sensory and reward information facilitates learning
Schoenfeld, G.; Kollmorgen, S.; Lewis, C. M.; Bethge, P.; Reuss, A. M.; Aguzzi, A.; Mante, V.; Helmchen, F.
10.1101/2021.12.28.474360 — neuroscience — Posted on 2021-12-28
201 A versatile active learning workflow for optimization of genetic and metabolic networks
Pandi, A.; Diehl, C.; Yazdizadeh Kharrazi, A.; Faure, L.; Scholz, S. A.; Nattermann, M.; Adam, D.; Chapin, N.; Foroughijabbari, Y.; Moritz, C.; Paczi, N.; Socorro Cortina, N.; Faulon, J.-L.; Erb, T. J.
10.1101/2021.12.28.474323 — synthetic biology — Posted on 2021-12-28
203 Integrated cytometry with machine learning applied to high-content imaging of human kidney tissue for in-situ cell classification and neighborhood analysis
Winfree, S.; McNutt, A. T.; Khochare, S.; Borgard, T. J.; Barwinska, D.; Sabo, A. R.; Ferkowicz, M. J.; Williams, J. C.; Lingeman, J. E.; Gulbronson, C. J.; Kelly, K. J.; Sutton, T. A.; Dagher, P. C.; Eadon, M. T.; Dunn, K. W.; El-Achkar, T. M.
10.1101/2021.12.27.474025 — physiology — Posted on 2021-12-28
204 In vitro cytokine expression analysis by droplet microfluidics
Wong, A. H.-H.; Akincilar, S. C.; Chua, J. Y. H.; Chanthira Morgan, D. d. K.; Hei, D.; Tergaonkar, V.
10.1101/2021.12.28.474355 — cancer biology — Posted on 2021-12-28
205 PTHrP Induces STAT5 Activation, Secretory Differentiation and Mammary Tumor Progression
Grinman, D. Y.; Boras-Granic, K.; Takyar, F. M.; Dann, P.; Hens, J. R.; Marmol, C.; Lee, J.; Choi, J.; Chodosh, L. A.; Garcia Sola, M. E.; Wysolmerski, J. J.
10.1101/2021.12.28.473846 — cancer biology — Posted on 2021-12-28
206 Structures of the Omicron Spike trimer with ACE2 and an anti-Omicron antibody
Yin, W.; Xu, Y.; Xu, P.; Cao, X.; Wu, C.; Gu, C.; He, X.; Wang, X.; Huang, S.; Yuan, Q.; Wu, K.; Hu, W.; Huang, Z.; Liu, J.; Wang, Z.; Jia, F.; Xia, K.; Liu, P.; Wang, X.; Song, B.; Zheng, J.; Jiang, H.; Cheng, X.; Jiang, Y.; Deng, S.-J.; Xu, H. E.
10.1101/2021.12.27.474273 — biophysics — Posted on 2021-12-28
207 Towards Generalizable Predictions for the Effects of Mutations on G-Protein Coupled Receptor Expression
Kuntz, C. P.; Woods, H.; McKee, A. G.; Zelt, N. B.; Mendenhall, J. L.; Meiler, J.; Schlebach, J. P.
10.1101/2021.12.28.474371 — biophysics — Posted on 2021-12-28
211 A Musculoskeletal Model of the Hand and Wrist Capable of Simulating Functional Tasks
McFarland, D. C.; Binder-Markey, B. I.; Nichols, J. A.; Wohlman, S. J.; de Bruin, M.; Murray, W. M.
10.1101/2021.12.28.474357 — bioengineering — Posted on 2021-12-28
212 Mapping the allosteric effects that define functional activity of SARS-CoV-2 specific antibodies
Tulsian, N. K.; Raghuvamsi, P. V.; Qian, X.; Yue, G.; D/O Shunmuganathan, B.; Samsudin, F.; Wong, Y. H.; Jianqing, L.; Purushotorman, K.; McQueen, M. K.; Wang, B.; Lescar, J.; Wang, C.-I.; Anand, G.; Bond, P. J.; MacAry, P. A.
10.1101/2021.12.27.474251 — biochemistry — Posted on 2021-12-28
213 Single-cell transcriptome atlas of Drosophila gastrula 2.0
Sakaguchi, S.; Okochi, Y.; Tanegashima, C.; Nishimura, O.; Uemura, T.; Kadota, M.; Naoki, H.; Kondo, T.
10.1101/2021.12.27.474293 — developmental biology — Posted on 2021-12-28
214 Revisiting rustrela virus - new cases of encephalitis and a solution to the capsid enigma
Pfaff, F.; Breithaupt, A.; Rubbenstroth, D.; Nippert, S.; Baumbach, C.; Gerst, S.; Langner, C.; Wylezich, C.; Ebinger, A.; Hoeper, D.; Ulrich, R.; Beer, M.
10.1101/2021.12.27.474043 — microbiology — Posted on 2021-12-28
215 Remdesivir, Molnupiravir and Nirmatrelvir remain active against SARS-CoV-2 Omicron and other variants of concern.
Vangeel, L.; De Jonghe, S.; Maes, P.; Slechten, B.; Raymenants, J.; Andre, E.; Neyts, J.; Jochmans, D.
10.1101/2021.12.27.474275 — microbiology — Posted on 2021-12-28
216 Super-immunity by broadly protective nanobodies to sarbecoviruses
Xiang, Y.; Huang, W.; Liu, H.; Sang, Z.; Nambulli, S.; Tubiana, J.; Williams, K. L.; Duprex, P.; Schneidman-Duhovny, D.; Wilson, I. A.; Taylor, D. J.; Shi, Y.
10.1101/2021.12.26.474192 — microbiology — Posted on 2021-12-28
217 SARS-CoV-2 Omicron-B.1.1.529 Variant leads to less severe disease than Pango B and Delta variants strains in a mouse model of severe COVID-19
Bentley, E. G.; Kirby, A.; Sharma, P.; Kipar, A.; Mega, D. F.; Bramwell, C.; Penrice-Randal, R.; Prince, T.; Brown, J. C.; Zhou, J.; Screaton, G. R.; Barclay, W. S.; Owen, A.; Hiscox, J. A.; Stewart, J. P.
10.1101/2021.12.26.474085 — microbiology — Posted on 2021-12-28
219 Intranasal inhibitor blocks Omicron and other variants of SARS-CoV-2
Mäkelä, A. R.; Ugurlu, H.; Hannula, L.; Salminen, P.; Kant, R.; Fagerlund, R.; Haveri, A.; Strandin, T.; Kareinen, L.; Hepojoki, J.; Levanov, L.; Pasternack, A.; Naves, R. A.; Ritvos, O.; Österlund, P.; Sironen, T.; Vapalahti, O.; Kipar, A.; Huiskonen, J. T.; Rissanen, I.; Saksela, K.
10.1101/2021.12.28.474326 — microbiology — Posted on 2021-12-28
221 Class I DISARM provides anti-phage and anti-conjugation activity by unmethylated DNA recognition
Aparicio-Maldonado, C.; Ofir, G.; Salini, A.; Sorek, R.; Nobrega, F. L.; Brouns, S. J.
10.1101/2021.12.28.474362 — microbiology — Posted on 2021-12-28
222 mGBP2 engages Galectin-9 and Cytoskeleton-associated Protein 4 for immunity against Toxoplasma gondii
Kravets, E.; Poschmann, G.; Haensch, S.; Weidtkamp-Peters, S.; Degrandi, D.; Stuehler, K.; Pfeffer, K.
10.1101/2021.12.28.474342 — immunology — Posted on 2021-12-28
223 Evaluation of maternal-infant dyad inflammatory cytokines in pregnancies affected by maternal SARS-CoV-2 infection in early and late gestation.
Taglauer, E.; Dhole, Y.; Boateng, J.; Snyder-Cappione, J. E.; Parker, S. E.; Clarke, K.; Juttukonda, L.; Devera, J.; Hunnewell, J.; Barnett, E.; Jia, H.; Yarrington, C.; Sabharwal, V.; Wachman, E.
10.1101/2021.12.26.472655 — immunology — Posted on 2021-12-28
224 Vaccine-breakthrough infection by the SARS-CoV-2 Omicron variant elicits broadly cross-reactive immune responses
Zhou, R.; To, K. K.-W.; Peng, Q.; Chan, J. M.-C.; Huang, H.; Yang, D.; Lam, B. H.-S.; Chuang, V. W.-M.; Cai, J.-P.; Liu, N.; Au, K.-K.; Tsang, O. T.-Y.; Yuen, K.-Y.; Chen, Z.
10.1101/2021.12.27.474218 — immunology — Posted on 2021-12-28
225 Structural analysis of the Spike of the Omicron SARS-COV-2 variant by Cryo-EM and implications for immune evasion
Ni, D.; Lau, K.; Turelli, P.; Raclot, C.; Beckert, B.; Nazarov, S.; Pojer, F.; Myasnikov, A.; Stahlberg, H.; Trono, D.
10.1101/2021.12.27.474250 — immunology — Posted on 2021-12-28
226 Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529
Zhou, T.; Wang, L.; Misasi, J.; Pegu, A.; Zhang, Y.; Harris, D. R.; Olia, A. S.; Talana, C. A.; Yang, E. S.; Chen, M.; Choe, M.; Shi, W.; Teng, I.-T.; Creanga, A.; Jenkins, C.; Leung, K.; Liu, T.; Stancofski, E.-S. D.; Stephens, T.; Zhang, B.; Tsybovsky, Y.; Graham, B.; Mascola, J. R.; Sullivan, N.; Kwong, P. D.
10.1101/2021.12.27.474307 — immunology — Posted on 2021-12-28
227 Booster vaccines protect hamsters with waning immunity from Delta VOC infection, disease, and transmission
Potts, K. G.; Noyce, R. S.; Gafuik, C.; John, C. M.; Todesco, H. M.; De Heuvel, E.; Favis, N.; Kelly, M. M.; Evans, D. H.; Mahoney, D. J.
10.1101/2021.12.27.474282 — immunology — Posted on 2021-12-28
228 Deciphering the quality of SARS-CoV-2 specific T-cell response associated with disease severity, immune memory and heterologous response
Perez-Gomez, A.; Gasca-Capote, M. C.; Vitalle, J.; Ostos, F. J.; Serna-Gallego, A.; Trujillo-Rodriguez, M.; Munoz-Muela, E.; Giraldez-Perez, T.; Praena-Segovia, J.; Navarro-Amuedo, M. D.; Paniagua-Garcia, M.; Garcia-Gutierrez, M.; Aguilar-Guisado, M.; Rivas-Jeremias, I.; Jimenez-Leon, M. R.; Bachiller, S.; Fernandez-Villar, A.; Perez-Gonzalez, A.; Gutierrez-Valencia, A.; Rafii-El-Idrissi Benhnia, M.; Weiskopf, D.; Sette, A.; Lopez-Cortes, L. F.; Poveda, E.; Ruiz-Mateos, E.
10.1101/2021.12.28.474325 — immunology — Posted on 2021-12-28
229 SARS-CoV-2 vaccination induces immunological memory able to cross-recognize variants from Alpha to Omicron
Tarke, A.; Coelho, C. H.; Zhang, Z.; Dan, J. M.; Yu, E. D.; Methot, N.; Bloom, N. I.; Goodwin, B.; Phillips, E.; Mallal, S.; Sidney, J.; Filaci, G.; Weiskopf, D.; da Silva Antunes, R.; Crotty, S.; Grifoni, A.; Sette, A.
10.1101/2021.12.28.474333 — immunology — Posted on 2021-12-28
230 Design, immunogenicity, and efficacy of a pan-sarbecovirus dendritic-cell targeting vaccine
Coleon, S.; Wiedemann, A.; Surenaud, M.; Lacabaratz, C.; Hue, S.; Prague, M.; Cervantes-Gonzalez, M.; Wang, Z.; Ellis, J.; Sansoni, A.; Pierini, C.; Bardin, Q.; Fabregue, M.; Sharkaoui, S.; Hoest, P.; Dupaty, L.; Picard, F.; Centlivre, M.; Ghosn, J.; Thiebaut, R.; Cardinaud, S.; Malissen, B.; Zurawski, G.; Zarubica, A.; Zurawski, S.; Godot, V.; Levy, Y.
10.1101/2021.12.28.474244 — immunology — Posted on 2021-12-28
231 A Multimodal Approach to Investigate the Neural Mechanisms of Real World Social Vision
Alreja, A.; Ward, M. J.; Ma, Q.; Richardson, M.; Russ, B.; Bickel, S.; Van Wouwe, N.; Gonzalez-Martinez, J. A.; Parker, L. S.; Neimat, J.; Schroeder, C.; Morency, L.-P.; Ghuman, A. S.
10.1101/2021.12.26.474173 — neuroscience — Posted on 2021-12-28
236 Prenatal immune stress induces a prolonged blunting of microglia activation that impacts striatal connectivity
Hayes, L. N.; An, K.; Carloni, E.; Li, F.; Vincent, E.; Paranjpe, M.; Dolen, G.; Goff, L. A.; Ramos, A.; Kano, S.-i.; Sawa, A.
10.1101/2021.12.27.473694 — neuroscience — Posted on 2021-12-28
237 Oncomodulin derived from regeneration-associated macrophages in dorsal root ganglia promotes axon regeneration in the spinal cord
Kwon, M.; Seo, Y.; Cho, H.; Choi, J.; Kim, H. S.; Oh, Y.; Kim, M.; Park, H. H.; Joe, E.-H.; Kwon, M.-H.; Kang, H. C.; Kim, B. G.
10.1101/2021.12.28.474322 — neuroscience — Posted on 2021-12-28
238 Size-dependent secondary nucleation and amplification of α-synuclein amyloid fibrils
Sakunthala, A.; Datta, D.; Navalkar, A.; Gadhe, L.; Kadu, P.; Patel, K.; Mehra, S.; Kumar, R.; Chatterjee, D.; Sengupta, K.; Padinhateeri, R.; Maji, S. K.
10.1101/2021.12.28.474324 — neuroscience — Posted on 2021-12-28
240 Identification of potential astrocytes in the teleost brain
Tan, G. J. H.; Cheow, K. W. B.; Ho, M. S. M.; Jesuthasan, S. J.
10.1101/2021.12.27.474298 — neuroscience — Posted on 2021-12-28
242 Mistimed feeding disrupts circadian rhythms of male mating behavior and female preovulatory LH surges in mice
Kukino, A.; Walbeek, T. J.; Sun, L. J.; Watt, A. T.; Park, J. H.; Kauffman, A. S.; Butler, M. P.
10.1101/2021.12.27.474267 — physiology — Posted on 2021-12-28
243 Dose-response relationship of pulmonary disorders by inhalation exposure to cross-linked water-soluble acrylic acid polymers in F344 rats
Takeda, T.; Yamano, S.; Goto, Y.; Hirai, S.; Furukawa, Y.; Kikuchi, Y.; Misumi, K.; Suzuki, M.; Takanobu, K.; Senoh, H.; Saito, M.; Kondo, H.; Kobashi, Y.; Okamoto, K.; Kishimoto, T.; Umeda, Y.
10.1101/2021.12.26.474221 — pharmacology and toxicology — Posted on 2021-12-28
250 Prescriptions For The Control Of A Clonal Invasive Species Using Demographic Models
Arroyo Cosultchi, G.; Golubov, J.; Solorzano, J. V.; Mandujano, M. d. C.
10.1101/2021.12.28.474361 — ecology — Posted on 2021-12-28
251 Chromatin state transition underlies the temporal changes in gene expression during cardiomyocyte maturation
Lin, C.-Y.; Chang, Y.-M.; Tseng, H.-Y.; Shih, Y.-L.; Yeh, H.-H.; Chen, P.-L.; Chen, C.-C.; Yan, Y.-T.; Kao, C.-F.
10.1101/2021.12.28.474318 — developmental biology — Posted on 2021-12-28
253 Construction and characterization of a genome-scale ordered mutant collection of Bacteroides thetaiotaomicron
Arjes, H. A.; Sun, J.; Liu, H.; Nguyen, T. H.; Culver, R. N.; Celis, A. I.; Walton, S. J.; Vasquez, K. S.; Yu, F. B.; Xue, K. S.; Newton, D. P.; Zermeno, R.; Weglarz, M.; Deutschbauer, A.; Huang, K.; Shiver, A. L.
10.1101/2021.12.27.474270 — microbiology — Posted on 2021-12-28
254 MIF-2/D-DT is an atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis
El Bounkari, O.; Zan, C.; Wagner, J.; Bugar, E.; Bourilhon, P.; Kontos, C.; Zarwel, M.; Sinitski, D.; Milic, J.; Jansen, Y.; Kempf, W.; Maegdefessel, L.; Hoffmann, A.; Brandhofer, M.; Bucala, R.; Megens, R. T. A.; Weber, C.; Kapurniotu, A.; Bernhagen, J.
10.1101/2021.12.28.474328 — immunology — Posted on 2021-12-28
255 Brain Morphometry and Chronic Inflammation in Bangladeshi Children Growing up in Extreme Poverty
Turesky, T. K.; Pirazzoli, L.; Shama, T.; Kakon, S. H.; Haque, R.; Islam, N.; Someshwar, A.; Gagoski, B.; Petri, W.; Nelson, C. A.; Gaab, N.
10.1101/2021.12.26.474220 — neuroscience — Posted on 2021-12-28
257 Single-cell analysis resolves the genetic program of primary vascular system formation in hybrid poplar
Conde, D.; Triozzi, P. M.; Pereira, W. J.; Schmidt, H. W.; Balmant, K. M.; Knaack, S. A.; Roy, S.; Dervinis, C.; Kirst, M.
10.1101/2021.12.28.474348 — plant biology — Posted on 2021-12-28
259 Mapping prion pathology in mice using quantitative imaging: an MRI study
Demetriou, E.; Tachrount, M.; Ellis, M.; Linehan, J.; Brandner, S.; Collinge, J.; Mead, S. H.; Shmueli, K.; Farrow, M.; Golay, X.
10.1101/2021.12.28.474373 — biophysics — Posted on 2021-12-28
260 Classification of Preeclamptic Placental Extracellular Vesicles Using Femtosecond Laser-fabricated Nanoplasmonic Sensors and Machine Learning
Kazemzadeh, M.; Martinez-Calderon, M.; Paek, S. Y.; Lowe, M.; Aguergaray, C.; Xu, W.; Chamley, L. W.; Broderick, N. G. R.; Hisey, C. L.
10.1101/2021.12.28.474354 — bioengineering — Posted on 2021-12-28
263 Structure of telomerase-bound CST with Polymerase α-Primase
He, Y.; He, S.; Chan, H.; Wang, Y.; Liu, B.; Susac, L.; Zhou, H.; Feigon, J.
10.1101/2021.12.28.474374 — molecular biology — Posted on 2021-12-28
264 Simple and cost-effective SNP genotyping method for discriminating subpopulations of the fish pathogen, Nocardia seriolae
Le, C. T.; Prince, E. P.; Sarovich, D. S.; Nguyen, T. T. A.; VuKhac, H.; Kurtboke, I.; Knibb, W.; Chen, S.-C.; Katouli, M.
10.1101/2021.12.28.474260 — microbiology — Posted on 2021-12-28
268 Dichotomous Feedback: A Signal Sequestration-based Feedback Mechanism for Biocontroller Design
Sootla, A.; Delalez, N.; Alexis, E.; Norman, A.; Steel, H.; Wadhams, G.; Papachristodoulou, A.
10.1101/2021.12.27.474252 — synthetic biology — Posted on 2021-12-27
270 Strain dependent structural effects and in vivo efficacy of enterovirus-D68 inhibitors
Lane, T. R.; Fu, J.; Sherry, B.; Tarbet, B.; Hurst, B.; Riabova, O.; Kazakova, E.; Egorova, A.; Clarke, P.; Leser, J. S.; Frost, J.; Rudy, M.; Tyler, K.; Klose, T.; Kuhn, R. J.; Makarov, V.; Ekins, S.
10.1101/2021.12.24.474126 — pharmacology and toxicology — Posted on 2021-12-27
271 Structural Evolution of the Ancient Enzyme, Dissimilatory Sulfite Reductase
Colman, D. R.; Labesse, G.; Swapna, G. V. T.; Stefanakis, J.; Montelione, G. T.; Boyd, E. S.; Royer, C. A.
10.1101/2021.12.28.474277 — biophysics — Posted on 2021-12-28
276 Comparative analysis of single cell lung atlas of bat, cat, tiger and pangolin
Wang, X.; Ou, Z.; Ding, P.; Sun, C.; Wang, D.; Zhu, J.; Wu, W.; Wei, Y.; Ding, X.; Luo, L.; Li, M.; Zhang, W.; Jin, X.; Sun, J.; Liu, H.; Chen, D.
10.1101/2021.12.26.473325 — bioinformatics — Posted on 2021-12-27
279 Structural basis for broad anti-phage immunity by DISARM
Bravo, J. P.; Maldonado, C. A.; Nobrega, F. L.; Brouns, S. J.; Taylor, D. W.
10.1101/2021.12.26.474123 — biochemistry — Posted on 2021-12-27
280 The SARS-CoV-2 nucleocapsid protein preferentially binds long and structured RNAs
Tai, C. E.; Tayeb-Fligelman, E.; Griner, S.; Salwinski, L.; Bowler, J. T.; Abskharon, R.; Cheng, X.; Seidler, P. M.; Jiang, Y. X.; Eisenberg, D. S.; Guo, F.
10.1101/2021.12.25.474155 — biochemistry — Posted on 2021-12-27
282 Defective linear and circular RNAs biogenesis in Huntington's disease: CAG repeat expansion hijacks neuronal splicing
Ayyildiz, D.; Monziani, A.; Tripathi, T.; Doering, J.; Bergonzoni, G.; Kerschbamer, E.; Di Leva, F.; Pennati, E.; Donini, L.; Kovalenko, M.; Zasso, J.; Conti, L.; Wheeler, V. C.; Dieterich, C.; Piazza, S.; Dassi, E.; Biagioli, M.
10.1101/2021.12.27.474266 — genetics — Posted on 2021-12-27
283 Discovery of a class of giant virus relatives displaying unusual functional traits and prevalent within plankton: the Mirusviricetes
Gaia, M.; Meng, L.; Pelletier, E.; Forterre, P.; Vanni, C.; Fernendez-Guerra, A.; Jaillon, O.; Wincker, P.; Ogata, H.; Delmont, T. O.
10.1101/2021.12.27.474232 — evolutionary biology — Posted on 2021-12-27
286 A combination of potently neutralizing monoclonal antibodies isolated from an Indian convalescent donor protects against the SARS-CoV-2 delta variant
Hingankar, N.; Deshpande, S.; Das, P.; Rizvi, Z. A.; Burns, A.; Barman, S.; Zhao, F.; Ansari, M. Y.; Mukherjee, S.; Torres, J. L.; Chattopadhyay, S.; Mehdi, F.; Sutar, J.; Rathore, D. K.; Pargai, K.; Singh, J.; Sonar, S.; Jakhar, K.; Bhattacharyya, S.; Mani, S.; Singh, S.; Dandotiya, J.; Kshetrapal, P.; Thiruvengadam, R.; Batra, G.; Medigeshi, G. R.; Ward, A.; Bhatnagar, S.; Awasthi, A.; Sok, D.; Bhattacharya, J.
10.1101/2021.12.25.474152 — immunology — Posted on 2021-12-27
287 Spatially bivariate EEG-neurofeedback can manipulate interhemispheric rebalancing of M1 excitability
Hayashi, M.; Okuyama, K.; Mizuguchi, N.; Hirose, R.; Okamoto, T.; Kawakami, M.; Ushiba, J.
10.1101/2021.12.15.472763 — neuroscience — Posted on 2021-12-29
292 Simultaneous Optimization of Excitation Wavelength and Emission Window for Semiconducting Polymer Nanoparticles to Improve Imaging Quality
Xue, D.; Zhou, H.; Lu, Z.; Zhang, Y.; Li, M.; Xu, Z.; Abudureheman, Z.; Feng, Z.; Li, L.; Liu, J.; Qian, J.; Li, G.
10.1101/2021.12.26.474182 — bioengineering — Posted on 2021-12-27
296 Improving the computation efficiency of polygenic risk score modeling: Faster in Julia
Faucon, A.; Samaroo, J.; Ge, T.; Davis, L. K.; Tao, R.; Cox, N. J.; Shuey, M. M.
10.1101/2021.12.27.474263 — genetics — Posted on 2021-12-27
297 Denitrification in foraminifera has ancient origins and is complemented by associated bacteria
Woehle, C.; Roy, S.; Glock, N.; Michels, J.; Wein, T.; Weissenbach, J.; Romero, D.; Hiebenthal, C.; Gorb, S.; Schoenfeld, J.; Dagan, T.
10.1101/2021.12.27.474233 — evolutionary biology — Posted on 2021-12-27
299 Encoding of odors by mammalian olfactory receptors
Vihani, A.; Nagai, M. H.; Juan, C.; de March, C. A.; Hu, X. S.; Pearson, J.; Matsunami, H.
10.1101/2021.12.27.474279 — neuroscience — Posted on 2021-12-28
301 Histone neutralization in a rat model of acute lung injury induced by double-hit lipopolysaccharide
ge, y.; wang, C.; Zhen, Y.; Luo, J.; chen, j.; wang, y.; wang, f.; wang, l.; lin, y.; shi, l.; yao, s.
10.1101/2021.12.26.474211 — pharmacology and toxicology — Posted on 2021-12-27
302 Phenotyping Polarization Dynamics Of Immune Cells Using A Lipid Droplet - Cell Pairing Microfluidic Platform
Pinon, L.; Ruyssen, N.; Pineau, J.; Mesdjian, O.; Cuvelier, D.; Allena, R.; Asnacios, S.; Asnacios, A.; Pierobon, P.; Fattaccioli, J.
10.1101/2021.12.22.473360 — biophysics — Posted on 2021-12-29
307 GenOtoScope: Towards automating ACMG classification of variants associated with congenital hearing loss
Melidis, D. P.; Landgraf, C.; Schmidt, G.; Schoener-Heinisch, A.; von Hardenberg, S.; Lesinski-Schiedat, A.; Nejdl, W.; Auber, B.
10.1101/2021.12.23.474074 — bioinformatics — Posted on 2021-12-29
308 mRNA-1273 vaccination protects against SARS-CoV-2 elicited lung inflammation in non-human primates
Waickman, A. T.; Victor, K.; Newell, K. L.; Li, T. L.; Friberg, H.; Foulds, K.; Roederer, M.; Bolton, D. L.; Currier, J. R.; Seder, R.
10.1101/2021.12.24.474132 — immunology — Posted on 2021-12-27
309 Early Computational Detection of Potential High Risk SARS-CoV-2 Variants
Beguir, K.; Skwark, M. J.; Fu, Y.; Pierrot, T.; Lopez Carranza, S. N.; Laterre, A.; Kadri, I.; Lui, B. G.; Sanger, B.; Liu, Y.; Poran, A.; Muik, A.; Sahin, U.
10.1101/2021.12.24.474095 — bioinformatics — Posted on 2021-12-27
310 Simple and cost-effective SNP genotyping method for discriminating subpopulations of the fish pathogen, Nocardia seriolae
Le, C. T.; Price, E. P.; Sarovich, D. S.; Nguyen, T. T. A.; Vu-Khac, H.; Kurtböke, I.; Knibb, W.; Chen, S.-C.; Katouli, M.
10.1101/2021.12.28.474260 — microbiology — Posted on 2021-12-29
313 Correlation scan: identifying genomic regions that affect genetic correlations applied to fertility traits
Olasege, B. S.; Porto-Neto, L. R.; Tahir, M. S.; Gouveia, G. C.; Canovas, A.; Hayes, B.; Fortes, M.
10.1101/2021.11.05.467409 — genetics — Posted on 2021-12-29
315 Functional interactomes of the Ebola virus polymerase identified by proximity proteomics in the context of viral replication
Fang, J.; Pietzsch, C.; Tsaprailis, G.; Crynen, G.; Cho, K. F.; Ting, A. Y.; Bukreyev, A.; de la Torre, J. C.; Saphire, E. O.
10.1101/2021.07.20.453153 — microbiology — Posted on 2021-12-28
319 Standardized genome-wide function prediction enables comparative functional genomics: a new application area for Gene Ontologies in plants
Fattel, L.; Psaroudakis, D.; Yanarella, C.; Chiteri, K.; Dostalik, H. A.; Joshi, P.; Starr, D. C.; Vu, H.; Wimalanathan, K.; Lawrence-Dill, C. J.
10.1101/2021.04.25.441366 — bioinformatics — Posted on 2021-12-28
320 Tree encroachment threatens the conservation potential and sustainability of U.S. rangelands
Morford, S. L.; Allred, B. W.; Twidwell, D.; Jones, M. O.; Maestas, J. D.; Naugle, D. E.
10.1101/2021.04.02.438282 — ecology — Posted on 2021-12-28
321 Moving bar of light evokes vectorial spatial selectivity in the immobile rat hippocampus
Purandare, C.; Dhingra, S.; Rios, R.; Vuong, C.; To, T.; Hachisuka, A.; Choudhary, K.; Mehta, M. R.
10.1101/2021.12.28.474337 — neuroscience — Posted on 2021-12-28
324 Chloroplast-localized translation for protein targeting in Chlamydomonas reinhardtii
Sun, Y.; Bakhtiari, S.; Valente-Paterno, M.; Wu, Y.; Law, C.; Dai, D.; Dhaliwal, J.; Bui, K. H.; Zerges, W.
10.1101/2021.12.27.474283 — cell biology — Posted on 2021-12-28
325 Clinical grade ACE2 effectively inhibits SARS-CoV-2 Omicron infections
Monteil, V.; Devignot, S.; Klingstroem, J.; Thalin, C.; Kellner, M. J.; Christ, W.; Havervall, S.; Mereiter, S.; Knapp, S.; Montserrat, N.; Braunsfeld, B.; Kozieradzki, I.; Ali, O. H.; Hagelkrueys, A.; Stadlmann, J.; Oostenbrink, C.; Wirnsberger, G.; Penninger, J. M.; Mirazimi, A.
10.1101/2021.12.25.474113 — molecular biology — Posted on 2021-12-27
331 SARS-CoV-2 Omicron neutralization by therapeutic antibodies, convalescent sera, and post-mRNA vaccine booster
Lusvarghi, S.; Pollett, S. D.; Neerukonda, S. N.; Wang, W.; Wang, R.; Vassell, R.; Epsi, N. J.; Fries, A. C.; Agan, B. K.; Lindholm, D. A.; Colombo, C. J.; Mody, R.; Ewers, E. C.; Lalani, T.; Ganesan, A.; Goguet, E.; Hollis-Perry, M.; Coggins, S. A.; Simons, M. P.; Katzelnick, L. C.; Wang, G.; Broder, C. C.; Tribble, D. R.; Bentley, L. M.; Eakin, A. E.; Erlandson, K. J.; Laing, E. D.; Burgess, T. H.; Mitre, E.; Weiss, C. D.
10.1101/2021.12.22.473880 — microbiology — Posted on 2021-12-28
334 A reference induced pluripotent stem cell line for large-scale collaborative studies
Pantazis, C. B.; Yang, A.; Lara, E.; McDonough, J. A.; Blauwendraat, C.; Peng, L.; Oguro, H.; Zou, J.; Sebesta, D.; Pratt, G.; Cross, E.; Blockwick, J.; Buxton, P.; Kinner-Bibeau, L.; Medura, C.; Tompkins, C.; Hughes, S.; Santiana, M.; Faghri, F.; Nalls, M. A.; Vitale, D.; Qi, Y. A.; Ramos, D. M.; Anderson, K. M.; Stadler, J.; Narayan, P.; Papademetriou, J.; Reilly, L.; Nelson, M. P.; Aggarwal, S.; Rosen, L. U.; Kirwan, P.; Pisupati, V.; Coon, S. L.; Scholz, S. W.; Coccia, E.; Sarrafha, L.; Ahfeldt, T.; Funes, S.; Bosco, D. A.; Beccari, M. S.; Cleveland, D. W.; Zanellati, M. C.; Basundra, R.;
10.1101/2021.12.15.472643 — neuroscience — Posted on 2021-12-28
336 SynergyFinder Plus: Toward Better Interpretation and Annotation of Drug Combination Screening Datasets
Zheng, S.; Wang, W.; Aldahdooh, J.; Malyutina, A.; Shadbahr, T.; Tanoli, Z.; Pessia, A.; Tang, J.
10.1101/2021.06.01.446564 — bioinformatics — Posted on 2021-12-28
339 Unconventional secretion of unglycosylated ORF8 is critical for the cytokine storm during SARS-CoV-2 infection
Lin, X.; Fu, B.; Xiong, Y.; Xing, N.; Xue, W.; Guo, D.; Y. Zaky, M.; Pavani, K. C.; Kunec, D.; Trimpert, J.; Wu, H.
10.1101/2021.12.03.471057 — microbiology — Posted on 2021-12-28
340 Human photoreceptors switch from autonomous axon extension to cell-mediated process pulling during synaptic marker redistribution.
Rempel, S. K.; Welch, M. J.; Ludwig, A. L.; Phillips, M. J.; Kancherla, Y.; Zack, D.; Gamm, D. M.; Gomez, T. M.
10.1101/2021.10.10.463810 — neuroscience — Posted on 2021-12-28
341 Structural and Dynamic Insights Into α-Synuclein Dimer Conformations
Zamel, J.; Chen, J.; Zaer, S.; Harris, P. D.; Drori, P.; Lebendiker, M.; Kalisman, N.; Dokholyan, N. V.; Lerner, E.
10.1101/795997 — biophysics — Posted on 2021-12-28
342 Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF
Corbeski, I.; Guo, X.; Eckhardt, B. V.; Fasci, D.; Graewert, M.; Wiegant, W. W.; Vreeken, K.; Wienk, H.; van Attikum, H.; Svergun, D. I.; Heck, A. J. R.; Boelens, R.; Sixma, T. K.; Mattiroli, F.; van Ingen, H.
10.1101/2021.12.24.474097 — biochemistry — Posted on 2021-12-28
343 Cell type-specific differential expression in spatial transcriptomics
Cable, D. M.; Murray, E.; Shanmugam, V.; Zhang, S.; Diao, M. Z.; Chen, H.; Macosko, E.; Irizarry, R. A.; Chen, F.
10.1101/2021.12.26.474183 — genomics — Posted on 2021-12-28
344 An empirical evaluation of genotype imputation of ancient DNA
Ausmees, K.; Sanchez-Quinto, F.; Jakobsson, M.; Nettelblad, C.
10.1101/2021.12.22.473913 — genomics — Posted on 2021-12-28
345 Mismatch repair disturbs meiotic class I crossover control
Cooper, T. J.; Crawford, M. R.; Hunt, L. J.; Marsolier-Kergoat, M.-C.; Llorente, B.; Neale, M. J.
10.1101/480418 — genetics — Posted on 2021-12-28
347 Suicidal chemotaxis in bacteria
Oliveira, N. M.; Wheeler, J. H. R.; Deroy, C.; Booth, S. C.; Walsh, E. J.; Durham, W. M.; Foster, K. R.
10.1101/2021.12.21.473623 — microbiology — Posted on 2021-12-28
350 Controlling pallidal oscillations in real-time in Parkinson's disease using evoked interference deep brain stimulation (eiDBS): proof of concept in the human
Escobar Sanabria, D.; Aman, J. E.; Zapata Amaya, V.; Johnson, L. A.; Farooqi, H.; Wang, J.; Hill, M.; Patriat, R.; Sovell-Brown, K.; Molnar, G. F.; Darrow, D.; McGovern, R.; Cooper, S. E.; Harel, N.; MacKinnon, C. D.; Park, M. C.; Vitek, J. L.
10.1101/2021.05.22.445251 — neuroscience — Posted on 2021-12-28
354 OTUD1 deubiquitylase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways
Oikawa, D.; Gi, M.; Kosako, H.; Shimizu, K.; Takahashi, H.; Shiota, M.; Hosomi, S.; Komakura, K.; Wanibuchi, H.; Tsuruta, D.; Sawasaki, T.; Tokunaga, F.
10.1101/2021.12.26.474226 — cell biology — Posted on 2021-12-27
356 Hierarchical control of microbial community assembly
Pontrelli, S.; Szabo, R.; Pollak, S.; Schwartzman, J. A.; Ledezma-Tejeida, D.; Cordero, O. X.; Sauer, U.
10.1101/2021.06.22.449372 — microbiology — Posted on 2021-12-27
357 Induced antigen-binding polyreactivity in human serum IgA
Gorshkova, E. N.; Lecerf, M.; Astrakhantseva, I. V.; Vasilenko, E. A.; Starkina, O. V.; Ilyukina, N. A.; Dimitrova, P. A.; Dimitrov, J. D.; Vassilev, T. L.
10.1101/2021.09.29.461938 — immunology — Posted on 2021-12-27
358 Flv3A facilitates O2 photoreduction and affects H2 photoproduction independently of Flv1A in diazotrophic Anabaena filaments
Santana Sanchez, A.; Nikkanen, L.; Toth, G.; Ermakova, M.; Kosourov, S.; Walter, J.; He, M.; Aro, E.-M.; Allahverdiyeva, Y.
10.1101/2021.12.15.472848 — plant biology — Posted on 2021-12-27
359 LINE-1 activation in the cerebellum drives ataxia
Takahashi, T.; Kudo, E.; Song, E.; Carvalho, F.; Yasumoto, Y.; Kong, Y.; Park, A.; Stoiljkovic, M.; Gao, X.-B.; Shanabrough, M.; Szigeti-Buck, K.; Liu, Z.-W.; Zhang, Y.; Sulkowski, P.; Glazer, P.; Kaczmarek, L.; Horvath, T.; Iwasaki, A.
10.1101/2021.12.03.471151 — neuroscience — Posted on 2021-12-27
360 Structurally and functionally distinct early antibody responses predict COVID-19 disease trajectory and mRNA vaccine response
Chakraborty, S.; Gonzalez, J. C.; Sievers, B. L.; Mallajosyula, V.; Dubey, M.; Cheng, Y.-L. B.; Tran, K. Q. T.; Chakraborty, S.; Cassidy, A.; Chen, S. T.; Sinnott, A.; Gelbart, T.; Golan, Y.; Prahl, M.; Singh, U.; Kim-Schulze, S.; Sherwood, R.; Zhang, S.; Marron, T. U.; Gnjatic, S.; Gaw, S. L.; Nadeau, K. C.; Merad, M.; Jagannathan, P.; Tan, G. S.; Wang, T. T.
10.1101/2021.05.25.445649 — immunology — Posted on 2021-12-27
362 Molecular organization and mechanics of single vimentin filaments revealed by super-resolution imaging
Vicente, F. N.; Lelek, M.; Tinevez, J.-Y.; Tran, Q. D.; Pehau-Arnaudet, G.; Zimmer, C.; Etienne-Manneville, S.; Giannone, G.; Leduc, C.
10.1101/2021.09.07.459174 — biophysics — Posted on 2021-12-27
363 Harnessing the Intrinsic Photochemistry of Isoxazoles for the Development of Chemoproteomic Crosslinking Methods
Lougee, M. G.; Pagar, V. V.; Kim, H. J.; Pancoe, S. X.; Mach, R. H.; Garcia, B.; Petersson, E. J.
10.1101/2021.12.23.473999 — biochemistry — Posted on 2021-12-27
365 Single amino-acid mutation in a Drosophila melanogaster ribosomal protein: an insight in uL11 transcriptional activity
Grunchec, H.; Deraze, J.; Dardalhon-Cumenal, D.; Ribeiro, V.; Coleno-Costes, A.; Dias, K.; Bloyer, S.; Mouchel-Vielh, E.; Peronnet, F.; Thomassin, H.
10.1101/2021.08.18.456895 — developmental biology — Posted on 2021-12-27
366 Developmental resilience of synaptome architecture
Tomas-Roca, L.; Qiu, Z.; Fransen, E.; Gokhale, R.; Bulovaite, E.; Price, D. J.; Komiyama, N.; Grant, S. G. N.
10.1101/2021.12.21.473638 — neuroscience — Posted on 2021-12-27
367 The initial response of females towards congeneric males matches the propensity to hybridise in Ophthalmotilapia.
Van Steenberge, M.; Jublier, N.; Kever, L.; Gresham, S.; Derycke, S.; Snoeks, J.; Parmentier, E.; Poncin, P.; Verheyen, E.
10.1101/2021.08.07.455508 — animal behavior and cognition — Posted on 2021-12-27
368 Molecular features underlying Pseudomonas aeruginosa persistence in human plasma
Janet-Maitre, M.; Pont, S.; Masson, F.; Trouillon, J.; Robert-Genthon, M.; Dumestre-Perard, C.; Elsen, S.; Moriscot, C.; Bardoel, B.; Rooijakkers, S.; Cretin, F.; Attree, I.
10.1101/2021.12.21.473675 — microbiology — Posted on 2021-12-27
370 A Combined Evidence Approach to Prioritize Nipah Virus Inhibitors
Bhardwaj, A.; Sharma, N.; Upadhyay, A.; Kalia, K.; Kumar, R.; Tuteja, K.; Paul, P. R.; Covernton, E.; Sharma, T.; Scaria, V.
10.1101/2020.03.12.977918 — bioinformatics — Posted on 2021-12-27
371 Zooplankton as a transitional host for Escherichia coli in freshwater
Di Cesare, A.; Riva, F.; Colinas, N.; Borgomaneiro, G.; Borin, S.; Cabello-Yeves, P. J.; Canale, C.; Cedraro, N.; Citterio, B.; Crotti, E.; Mangiaterra, G.; Mapelli, F.; Mondino, V.; Vignaroli, C.; Quaranta, W.; Corno, G.; Fontaneto, D.; Eckert, E. M.
10.1101/2021.12.23.474077 — ecology — Posted on 2021-12-27
373 Rapid selection of P323L in the SARS-CoV-2 polymerase (NSP12) in humans and non-human primate models and confers a large plaque phenotype
Dong, X.; Goldswain, H.; Penrice-Randal, R.; Shawli, G.; Prince, T.; Williamson, M. K.; Randle, N.; Jones, B.; Salguero, F. J.; Tree, J.; Hall, Y.; Hartley, C.; Erdmann, M.; Bazire, J.; Jearanaiwitayakul, T.; ISARIC4C investigators, ; Semple, M. G.; Openshaw, P.; Baillie, J. K.; Emmett, S. R.; Digard, P.; Matthews, D. A.; Turtle, L.; Darby, A.; Davidson, A. D.; Carroll, M.; Hiscox, J. A.
10.1101/2021.12.23.474030 — microbiology — Posted on 2021-12-27
374 Neocortical pyramidal neurons with axons emerging from dendrites are frequent in non-primates, but rare in monkey and human
Wahle, P.; Sobierajski, E.; Gasterstädt, I.; Lehmann, N.; Weber, S.; H. R. Lübke, J.; Engelhardt, M.; Distler, C.; Meyer, G.
10.1101/2021.12.24.474100 — neuroscience — Posted on 2021-12-27
378 Multiple types of genomic variation contribute to adaptive traits in the mustelid subfamily Guloninae
Derezanin, L.; Blazyte, A.; Dobrynin, P.; Duchene, D. A.; Grau, J. H.; Jeon, S.; Kliver, S.; Koepfli, K.-P.; Meneghini, D.; Preick, M.; Tomarovsky, A.; Totikov, A.; Fickel, J.; Förster, D. W.
10.1101/2021.09.27.461651 — evolutionary biology — Posted on 2021-12-27
379 A subset of Memory B-derived antibody repertoire from 3-dose vaccinees is ultrapotent against diverse and highly transmissible SARS-CoV-2 variants, including Omicron
Wang, K.; Jia, Z.; Bao, L.; Wang, L.; Cao, L.; Chi, H.; Hu, Y.; Li, Q.; Jiang, Y.; Zhu, Q.; Deng, Y.; Liu, P.; Wang, N.; Wang, L.; Liu, M.; Li, Y.; Zhu, B.; Fan, K.; Fu, W.; Yang, P.; Pei, X.; Cui, Z.; Qin, L.; Ge, P.; Wu, J.; Liu, S.; Chen, Y.; Huang, W.; Qin, C.; Wang, Y.; Qin, C.; Wang, X.
10.1101/2021.12.24.474084 — microbiology — Posted on 2021-12-26
382 Nuclear Progestin Receptor Mediated Linkage of Blood Coagulation and Ovulation
Huang, J.; Chao, S.; Liu, T. D.; Zhao, N. N.; Shavit, J. A.; Zhu, Y.; Chen, S. X.
10.1101/2021.11.08.467707 — physiology — Posted on 2021-12-27
383 Impacts of the COVID-19 Pandemic on a Human Research Islet Program
Dafoe, T. J.; dos Santos, T.; Spigelman, A. F.; Lyon, J.; Smith, N.; Bautista, A.; MacDonald, P. E.; Manning Fox, J. E.
10.1101/2021.12.24.474114 — physiology — Posted on 2021-12-27
385 Flooding tolerance of four tropical peatland tree species in a nursery trial
Tata, H. L.; Nuroniah, H. S.; Ahsania, D. A.; Anggunira, H.; Hidayati, N.; Pratama, M.; Istomo, I.; Chimner, R. A.; Kolka, R. K.; van Noordwijk, M.; All authors have been added in the main author list.,
10.1101/2021.12.26.474202 — plant biology — Posted on 2021-12-26
386 CREBBP/EP300 acetyltransferase inhibition disrupts FOXA1-bound enhancers to inhibit the proliferation of ER+ breast cancer cells
Conery, A.; Bommi-Reddy, A.; Park-Chouinard, S.; Mayhew, D. N.; Terzo, E.; Hingway, A.; Steinbaugh, M. J.; Wilson, J. E.; Sims, R. J.
10.1101/2021.12.26.474204 — cancer biology — Posted on 2021-12-26
391 High-resolution screening for marine prokaryotic and eukaryotic taxa with selective preference for PE and PET surfaces
Marsay, K.; Koucherov, Y.; Davidov, K.; Iankelevich Kounio, E.; Itzahri, S.; Salmon-Divon, M.; Oren, M.
10.1101/2021.12.26.474179 — microbiology — Posted on 2021-12-26
393 The omicron (B.1.1.529) SARS-CoV-2 variant of concern does not readily infect Syrian hamsters
Abdelnabi, R.; Foo, C. S.-Y.; Zhang, X.; Lemmens, V.; Maes, P.; Slechten, B.; Raymenants, J.; Andre, E.; Weynand, B.; Dallmeier, K.; Neyts, J.
10.1101/2021.12.24.474086 — microbiology — Posted on 2021-12-26
394 Convalescence from prototype SARS-CoV-2 protects Syrian hamsters from disease caused by the Omicron variant
Ryan, K. A.; Watson, R. J.; Bewley, K. R.; Burton, C. A.; Carnell, O.; Cavell, B. E.; Challis, A. R.; Coombes, N. S.; Emery, K.; Fell, R.; Fotheringham, S. A.; Gooch, K. E.; Gowan, K.; Handley, A.; Harris, D. J.; Humphreys, R.; Johnson, R.; Knott, D.; Lister, S.; Morley, D.; Ngabo, D.; Osman, K. L.; Paterson, J.; Penn, E. J.; Pullen, S. T.; Richards, K. S.; Shaik, I.; Summers, S.; Thomas, S. R.; Weldon, T.; Wiblin, N. R.; Vipond, R.; Hallis, B.; Funnell, S. G. P.; Hall, Y.
10.1101/2021.12.24.474081 — microbiology — Posted on 2021-12-26
395 Two doses of mRNA vaccine elicit cross-neutralizing memory B-cells against SARS-CoV-2 Omicron variant
Kotaki, R.; Adachi, Y.; Moriyama, S.; Onodera, T.; Fukushi, S.; Nagakura, T.; Tonouchi, K.; Terahara, K.; Sun, L.; Takano, T.; Nishiyama, A.; Shinkai, M.; Oba, K.; Nakamura-Uchiyama, F.; Shimizu, H.; Suzuki, T.; Matsumura, T.; Isogawa, M.; Takahashi, Y.
10.1101/2021.12.24.474091 — immunology — Posted on 2021-12-26
400 The influence of non-neural factors on BOLD signal magnitude
Kurzawski, J. W.; Gulban, O. F.; Jamison, K. W.; Winawer, J.; Kay, K.
10.1101/2021.12.26.474185 — neuroscience — Posted on 2021-12-26
401 Distinct cDC subsets co-operate in CD40 agonist response while suppressive microenvironments and lack of antigens subvert efficacy
Murgaski, A.; Kiss, M.; Van Damme, H.; Kancheva, D.; Vanmeerbeek, I.; Keirsse, J.; Hadadi, E.; Brughmans, J.; Arnouk, S. M.; Hamouda, A. E. I.; Debraekeleer, A.; Bosteels, V.; Elkrim, Y.; Boon, L.; Hoves, S.; Vandamme, N.; Deschoemaeker, S.; Janssens, S.; Garg, A. D.; Schmittnaegel, M.; Ries, C. H.; Laoui, D.
10.1101/2021.12.25.474021 — cancer biology — Posted on 2021-12-26
402 Survival and detection of bivalve transmissible neoplasia from the soft-shell clam Mya arenaria (MarBTN) in seawater
Giersch, R. M.; Hart, S. F.; Reddy, S. G.; Yonemitsu, M. A.; Orellana Rosales, M. J.; Korn, M.; Geleta, B. M.; Countway, P. D.; Fernandez Robledo, J. A.; Metzger, M. J.
10.1101/2021.12.25.473725 — cancer biology — Posted on 2021-12-26
403 A unifying perspective of the ultrafast photo-dynamics of Orange Carotenoid Protein from Synechocystis: peril of high-power excitation, existence of different S* states and influence of tagging
Nizinski, S.; Wilson, A.; Uriarte, L. M.; Ruckebusch, C.; Andreeva, E.; Schlichting, I.; Colletier, J.-P.; Kirilovsky, D.; Burdzinski, G.; Sliwa, M.
10.1101/2021.12.26.474187 — biophysics — Posted on 2021-12-26
404 In vitro and in vivo NIR Fluorescence Lifetime Imaging with a time-gated SPAD camera
Smith, J. T.; Rudkouskaya, A.; Gao, S.; Gupta, J. M.; Ulku, A.; Bruschini, C.; Charbon, E.; Weiss, S.; Barroso, M.; Intes, X.; Michalet, X.
10.1101/2021.12.26.474189 — bioengineering — Posted on 2021-12-26
405 Cell type-specific differential expression for spatial transcriptomics
Cable, D. M.; Murray, E.; Shanmugam, V.; Zhang, S.; Diao, M. Z.; Chen, H.; Macosko, E.; Irizarry, R. A.; Chen, F.
10.1101/2021.12.26.474183 — genomics — Posted on 2021-12-26
407 Alveoli form directly by budding led by a single epithelial cell
Gillich, A.; St. Julien, K. R.; Brownfield, D. G.; Travaglini, K. J.; Metzger, R. J.; Krasnow, M. A.
10.1101/2021.12.25.474174 — developmental biology — Posted on 2021-12-26
408 Antibacterial T6SS effectors with a VRR-Nuc domain induce target cell death via DNA Double-Strand Breaks
Hespanhol, J. T.; Sanchez-Limache, D. E.; Nicastro, G. G.; Mead, L.; Llontop, E. E.; Chagas-Santos, G.; Farah, C. S.; de Souza, R. F.; Galhardo, R. d. S.; Lovering, A.; Bayer-Santos, E.
10.1101/2021.12.26.474169 — microbiology — Posted on 2021-12-26
409 COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis
Sinha, S.; Castillo, V.; Espinoza, C. R.; Tindle, C.; Fonseca, A. G.; Dan, J. M.; Katkar, G. D.; Das, S.; Sahoo, D.; Ghosh, P.
10.1101/2021.11.28.470269 — immunology — Posted on 2021-12-26
412 Effect of OTR4120 on pulmonary fibrosis in mice
Charef, S.; Mejdoubi Charef, N.; Chiappini, F.; Papy Garcia, D.; Barritault, D.
10.1101/2021.10.24.465650 — physiology — Posted on 2021-12-26
413 APOBEC mutagenesis is low in most types of non-B DNA structures, unlike other types of cancer mutagenesis
Ponomarev, G. V.; Fatykhov, B.; Nazarov, V. A.; Abasov, R.; Shvarov, E.; Landik, N.-V.; Denisova, A. A.; Chervova, A. A.; Gelfand, M. S.; Kazanov, M. D.
10.1101/2021.10.12.464135 — cancer biology — Posted on 2021-12-26
414 Regulation of DNA damage response by trimeric G-protein Signaling
Abd El-Hafeez, A. A.; Sun, N.; Chakraborty, A.; Ear, J.; Roy, S.; Chamarthi, P.; Rajapakse, N.; Das, S.; Luker, K. E.; Hazra, T. K.; Luker, G. D.; Ghosh, P.
10.1101/2021.07.21.452842 — cancer biology — Posted on 2021-12-26
418 Gdnf, a germ cell-derived factor, regulates zebrafish germ cell stemness through the creation of new spermatogonial niches (germ and Sertoli cells) and inhibition of spermatogonial differentiation in an autocrine and paracrine manners
Doretto, L.; Butzge, A. J.; Nakajima, R. T.; Martinez, E. R. M.; Marques, B.; Rodrigues, M. S.; Rosa, I. F.; Ricci, J. M. B.; Tovo-Neto, A.; Costa, D.; Malafaia, G.; Shao, C.; Nobrega, R. H.
10.1101/2021.12.25.474164 — cell biology — Posted on 2021-12-26
419 Protein scaffold-based multimerization of soluble ACE2 efficiently blocks SARS-CoV-2 infection in vitro and in vivo
Kayabolen, A.; Akcan, U.; Ozturan, D.; Ulbegi-Polat, H.; Sahin, G. N.; Pinarbasi Degirmenci, N.; Bayraktar, C.; Soyler, G.; Sarayloo, E.; Nurtop, E.; Ozer, B.; Guney-Esken, G.; Barlas, T.; Yildirim, I. S.; Dogan, O.; Karahuseyinoglu, S.; Lack, N. A.; Kaya, M.; Albayrak, C.; Can, F.; Solaroglu, I.; Bagci-Onder, T.
10.1101/2021.01.04.425128 — molecular biology — Posted on 2021-12-26
420 Scrutiny of human lung infection by SARS-CoV-2 and associated human immune responses in humanized mice
Sun, R.; Zhao, Z.; Fu, C.; Wang, Y.; Guo, Z.; Zhang, C.; Liu, L.; Zhang, C.; Shu, C.; He, J.; Hua, S.; Gao, Y.; Hu, Z.; Yang, Y.-G.
10.1101/2021.11.05.466755 — immunology — Posted on 2021-12-26
424 Reprogrammed iBlastoids contain amnion-like cells but not trophectoderm
Zhao, C.; Plaza Reyes, A.; Schell, J. P.; Weltner, J.; Ortega, N.; Zheng, Y.; Bjorklund, A. K.; Rossant, J.; Fu, J.; Petropoulos, S.; Lanner, F.
10.1101/2021.05.07.442980 — developmental biology — Posted on 2021-12-26
428 In vitro evolution predicts emerging CoV-2 mutations with high affinity for ACE2 and cross-species binding
Bate, N.; Savva, C. G.; Moody, P. C.; Brown, E. A.; Ball, J. K.; Schwabe, J. W.; Sale, J.; Brindle, N.
10.1101/2021.12.23.473975 — biochemistry — Posted on 2021-12-25
430 SHERRY2: A method for rapid and sensitive single cell RNA-seq
Di, L.; Liu, B.; Lyu, Y.; Zhao, S.; Pang, Y.; Zhang, C.; Wang, J.; Qi, H.; Shen, J.; Huang, Y.
10.1101/2021.12.25.474161 — genomics — Posted on 2021-12-25
432 An ultrapotent RBD-targeted biparatopic nanobody neutralizes broad SARS-CoV-2 variants
Chi, X.; Zhang, X.; Pan, S.; Yu, Y.; Lin, T.; Duan, H.; Liu, X.; Chen, W.; Yang, X.; Ding, Q.; Wang, J.; Yang, W.
10.1101/2021.12.25.474052 — microbiology — Posted on 2021-12-25
433 IL4I1 binds to TMPRSS13 and competes with SARS-Cov2 Spike
Gatineau, J.; Nidercorne, C.; Dupont, A.; Puiffe, M.-L.; Cohen, J. L.; Molinier-Frenkel, V.; Niedergang, F.; Castellano, F.
10.1101/2021.12.23.473686 — immunology — Posted on 2021-12-25
434 Human KIR+CD8+ T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19
Li, J.; Zaslavsky, M. E.; Su, Y.; Sikora, M.; van Unen, V.; Christophersen, A.; Chiou, S.-H.; Chen, L.; Li, J.; Ji, X.; Wilhelmy, J.; McSween, A.; Palanski, B. A.; Mallajosyula, V.; Dhondalay, G.; Bhamidipati, K.; Pai, J.; Kipp, L.; Dunn, J.; Hauser, S.; Oksenberg, J.; Satpathy, A.; Robinson, W.; Steinmetz, L.; Khosla, C.; Utz, P.; Sollid, L. M.; Heath, J.; Fernandez-Becker, N.; Nadeau, K.; Saligrama, N.; Davis, M.
10.1101/2021.12.23.473930 — immunology — Posted on 2021-12-25
442 Establishment of a stable SARS-CoV-2 replicon system for application in high-throughput screening.
Tanaka, T.; Saito, A.; Suzuki, T.; Miyamoto, Y.; Takayama, K.; Okamoto, T.; Moriishi, K.
10.1101/2021.12.23.474055 — microbiology — Posted on 2021-12-25
444 Sub-sampling of cues in associative learning
Perez, O. D.; Vogel, E. H.; Narasiwodeyar, S.; Soto, F. A.
10.1101/713420 — animal behavior and cognition — Posted on 2021-12-25
446 NCoR1 and SMRT fine-tune inflammatory versus tolerogenic balance in dendritic cells by differentially regulating STAT3 signaling
Raghav, S. K.; Jha, A.; Ahad, A.; Mishra, G. P.; Sen, K.; Smita, S.; Minz, A. P.; Biswas, V. K.; Tripathy, A.; Senapati, S. B.; Gupta, B.; Orbea, H. A.
10.1101/2021.03.11.434976 — immunology — Posted on 2021-12-25
449 OX40 agonism enhances efficacy of PD-L1 checkpoint blockade by shifting the cytotoxic T cell differentiation spectrum
Beyrend, G.; van der Sluis, T. C.; van der Gracht, E. T. I.; Abdelaal, T.; Jochems, S. P.; Belderbos, R. A.; Wesselink, T. H.; van Duikeren, S.; van Haften, F. J.; Redeker, A.; Beyranvand Nejad, E.; Camps, M.; Franken, K. L. M. C.; Linssen, M. M.; Hohenstein, P.; de Miranda, N. F. C. C.; Mei, H.; Bins, A. D.; Haanen, J. B. A. G.; Aerts, J. G.; Ossendorp, F.; Arens, R.
10.1101/2021.12.24.474145 — immunology — Posted on 2021-12-25
451 Excitatory/inhibitory imbalance in autism: the role of glutamate and GABA gene-sets in symptoms and cortical brain structure
Hollestein, V.; Poelmans, G.; Forde, N.; Beckmann, C. F.; Ecker, C.; Mann, C.; Schaefer, T.; Moessnang, C.; Baumeister, S.; Banaschewski, T.; Bourgeron, T.; Loth, E.; Dell'Acqua, F.; Murphy, D.; Tillmann, J.; Charman, T.; Jones, E. J. H.; Mason, L.; Ambrosino, S.; Holt, R.; Bolte, S.; Buitelaar, J. J. K.; Naaijen, J.
10.1101/2021.12.20.473501 — neuroscience — Posted on 2021-12-25
452 Functional Network Connectivity Imprint In Febrile Seizures
Acharya, U. V.; Kulanthaivelu, K.; Panda, R.; Saini, J.; Gupta, A. K.; Sankaran, B. P.; Raghavendra, K.; Mundlamuri, R. C.; Sinha, S.; Keshavamurthy, M.; Bharath, R. D.
10.1101/2021.12.18.473280 — neuroscience — Posted on 2021-12-25
453 Improved immunoassay sensitivity and specificity using single-molecule colocalization
Hariri, A. A.; Newman, S. S.; Tan, S.; Mamerow, D.; Eisenstein, M.; Dunn, A.; Soh, H. T.
10.1101/2021.12.24.474141 — biophysics — Posted on 2021-12-25
454 Terpene volatiles mediates the chemical basis of blueberry aroma and consumer acceptability
Ferrao, L. F. V.; Sater, H.; Lyrene, P.; Amadeu, R. R.; Sims, C.; Tieman, D.; Munoz, P. R.
10.1101/2021.12.24.474137 — genetics — Posted on 2021-12-25
457 Multi-omics and 3D-imaging reveal bone heterogeneity and unique calvaria cells in neuroinflammation
Kolabas, Z. I.; Kuemmerle, L. B.; Perneczky, R.; Foerstera, B.; Buttner, M.; Caliskan, O. S.; Ali, M.; Rong, Z.; Mai, H.; Hummel, S.; Bartos, L. M.; Biechele, G.; Zatcepin, A.; Albert, N. L.; Unterrainer, M.; Gnoerich, J.; Zhao, S.; Khalin, I.; Rauchmann, B.-S.; Molbay, M.; Sterr, M.; Kunze, I.; Stanic, K.; Besson-Girard, S.; Kopczak, A.; Katzdobler, S.; Palleis, C.; Gokce, O.; Lickert, H.; Steinke, H.; Bechmann, I.; Buerger, K.; Levin, J.; Haass, C.; Dichgans, M.; Havla, J.; Kumpfel, T.; Kerschensteiner, M.; Simons, M.; Plesnila, N.; Krahmer, N.; Bhatia, H. S.; Erener, S.; Hellal, F.; Brendel
10.1101/2021.12.24.473988 — cell biology — Posted on 2021-12-25
458 Rapid and Durable Protection Against Marburg Virus with a Single-Shot ChAd3-MARV GP Vaccine
Hunegnaw, R.; Honko, A.; Wang, L.; Carr, D.; Murray, T.; Shi, W.; Dullan, C. N. M.; Foulds, K. E.; Agans, K. N.; Cross, R. W.; Geisbert, J. B.; Geisbert, T. W.; Cheng, C.; Ploquin, A.; Stanley, D. A.; Nabel, G. J.; Sullivan, N. J.
10.1101/2021.12.22.472410 — immunology — Posted on 2021-12-25
464 LotuS2: An ultrafast and highly accurate tool for amplicon sequencing analysis
Ozkurt, E.; Fritscher, J.; Soranzo, N.; Ng, D. Y. K.; Davey, R. P.; Bahram, M.; Hildebrand, F.
10.1101/2021.12.24.474111 — bioinformatics — Posted on 2021-12-24
466 Coupled protein quality control during nonsense mediated mRNA decay
Inglis, A. J.; Guna, A.; Merchan, A. G.; Pal, A.; Esantsi, T. K.; Keys, H. R.; Frenkel, E. M.; Oania, R.; Weissman, J. S.; Voorhees, R. M.
10.1101/2021.12.22.473893 — molecular biology — Posted on 2021-12-24
467 Stress-impaired reward pathway promotes distinct feeding behavior patterns
Fujioka, Y.; Kawai, K.; Endo, K.; Ishibashi, M.; Iwade, N.; Tuerde, D.; Kaibuchi, K.; Yamashita, T.; Yamanaka, A.; Katsuno, M.; Watanabe, H.; Ishigaki, S.; Sobue, G.
10.1101/2021.12.08.471524 — neuroscience — Posted on 2021-12-24
468 Systemic influences of mammary cancer on monocytes in mice
Robinson, A.; Burgess, M.; Webb, S.; Louwe, P.; Ouyang, Z.; Skola, D.; Han, C. Z.; Batada, N. N.; Gonzalez, V.; Cassetta, L.; Glass, C. K.; Jenkins, S. J.; Pollard, J. W.
10.1101/2021.12.24.474104 — cancer biology — Posted on 2021-12-24
469 Phenotyping single-cell motility in microfluidic confinement
Bentley, S. A.; Anagnostidis, V.; Laeverenz Schlogelhofer, H.; Gielen, F.; Wan, K. Y.
10.1101/2021.12.24.474109 — biophysics — Posted on 2021-12-24
471 Genomic bases of insularity and ecological divergence in barn owls (Tyto alba) of the Canary Islands
Cumer, T.; Machado, A. P.; Siverio, F.; Cherkaoui, S. I.; Roque, I.; Lourenco, R.; Charter, M.; Roulin, A.; Goudet, J.
10.1101/2021.12.24.473866 — evolutionary biology — Posted on 2021-12-24
474 Robust differentiation of human enteroendocrine cells from intestinal stem cells
Zeve, D.; Stas, E.; de Sousa Casal, J.; Mannam, P.; Qi, W.; Yin, X.; Dubois, S.; Shah, M. S.; Syverson, E. P.; Hafner, S.; Karp, J. M.; Carlone, D. L.; Ordovas-Montanes, J.; Breault, D. T.
10.1101/2020.09.21.303990 — developmental biology — Posted on 2021-12-24
477 Neural correlates of individual odor preference in Drosophila
Churgin, M.; Lavrentovich, D.; Smith, M. A.-Y.; Gao, R.; Boyden, E. S.; de Bivort, B. L.
10.1101/2021.12.24.474127 — neuroscience — Posted on 2021-12-24
478 Hypodopaminergic state of the nigrostriatal pathway drives compulsive alcohol use
Goutaudier, R.; Mallet, D.; Bartolomucci, M.; Carcenac, C.; Vossier, F.; Dufourd, T.; Boulet, S.; Derensart, C.; Chovelon, B.; Carnicella, S.
10.1101/2021.12.24.474124 — neuroscience — Posted on 2021-12-24
479 An early Cambrian polyp reveals an anemone-like ancestor for medusozoan cnidarians
Zhao, Y.; Parry, L.; Vinther, J.; Dunn, F. S.; Li, Y.; Wei, F.; Hou, X.; Cong, P.
10.1101/2021.12.24.474121 — paleontology — Posted on 2021-12-24
481 The LOTUS Initiative for Open Natural Products Research: Knowledge Management through Wikidata
Rutz, A.; Sorokina, M.; Galgonek, J.; Mietchen, D.; Willighagen, E.; Gaudry, A.; Graham, J. G.; Stephan, R.; Page, R.; Vondrasek, J.; Steinbeck, C.; Pauli, G.; Wolfender, J.-L.; Bisson, J.; Allard, P.-M.
10.1101/2021.02.28.433265 — bioinformatics — Posted on 2021-12-24
482 Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF
Corbeski, I.; Guo, X.; Eckhardt, B. V.; Fasci, D.; Graewert, M.; Wiegant, W. W.; Vreeken, K.; Wienk, H.; van Attikum, H.; Svergun, D. I.; Heck, A. J. R.; Boelens, R.; Sixma, T. K.; Mattiroli, F.; van Ingen, H.
10.1101/2021.12.24.474097 — biochemistry — Posted on 2021-12-24
483 Active enhancers strengthen insulation by RNA-mediated CTCF binding at TAD boundaries
Islam, Z.; Saravanan, B.; Walavalkar, K.; Thakur, J.; Farooq, U.; Singh, A. K.; Sabarinathan, R.; Pandit, A.; Henikoff, S.; Notani, D.
10.1101/2021.07.13.452118 — genomics — Posted on 2021-12-24
485 Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617
Peng, L.; Hu, Y.; Mankowski, M.; Ren, P.; Chen, R.; Wei, J.; Zhao, M.; Li, T.; Tripler, T.; Ye, L.; Chow, R.; Fang, Z.; Wu, C.; Dong, M.; Cook, M.; Wang, G.; Clark, P.; Nelson, B.; Klein, D.; Sutton, R.; Diamond, M.; Wilen, C.; Xiong, Y.; Chen, S.
10.1101/2021.12.21.473733 — immunology — Posted on 2021-12-24
486 Single cell RNA-seq identifies developing corneal cell fates in the human cornea organoid
Maiti, G.; Rocha Monteiro de Barros, M.; Hu, N.; Roshan, M.; Wahlin, K. J.; Chakravarti, S.
10.1101/2021.12.23.471999 — developmental biology — Posted on 2021-12-24
487 MEMO: Mass Spectrometry-based Sample Vectorization to Explore Chemodiverse Datasets
Gaudry, A.; Huber, F.; Nothias, L.-F.; Cretton, S.; Kaiser, M.; Wolfender, J.-L.; Allard, P.-M.
10.1101/2021.12.24.474089 — bioinformatics — Posted on 2021-12-24
490 Structure, dynamics, and inhibition of Staphylococcus aureus m1A22-tRNA methyltransferase
Sweeney, P.; Crowe, A.; Kumar, A.; Raju, D.; Krishna, N. B.; Sutherland, E.; Leo, C. J.; Fisher, G.; Lalitha, R.; Muthuraj, L.; Sigamani, G.; Oehler, V.; Synowsky, S.; Shirran, S. L.; Gloster, T. M.; Czekster, C. M.; Kumar, P.; da Silva, R. G.
10.1101/2021.12.24.474102 — biochemistry — Posted on 2021-12-24
491 An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR mediated homologous recombination
Kanca, O.; Zirin, J.; Hu, Y.; Tepe, B.; Dutta, D.; Lin, W.-W.; Ma, L.; Ge, M.; Zuo, Z.; Liu, L.-P.; Levis, R. W.; Perrimon, N.; Bellen, H. J.
10.1101/2021.12.24.474112 — genetics — Posted on 2021-12-24
492 PCBP1 Deficient Pigs Hold the Potential to Inhibit CSFV Infection
Qi, C.; Pang, D.; Yang, K.; Jiao, S.; Wu, H.; Zhao, C.; Hu, L.; Li, F.; Zhou, J.; Yang, L.; Lv, D.; Tang, X.; Ouyang, H.; Xie, Z.
10.1101/2021.12.23.474075 — molecular biology — Posted on 2021-12-24
495 Ultra-deep through-skull mouse brain imaging via the combination of skull optical clearing and three-photon microscopy
He, M.; Li, D.; Zheng, Z.; Zhang, H.; Wu, T.; Geng, W.; Hu, Z.; Feng, Z.; Peng, S.; Zhu, L.; Xi, W.; Zhu, D.; Qian, J.
10.1101/2021.12.20.473469 — neuroscience — Posted on 2021-12-24
496 Pharmacological blockade of muscle afferents and perception of effort: a systematic review with meta-analysis
Bergevin, M.; Steele, J.; Payen de la Garanderie, M.; Feral-Basin, C.; Marcora, S. M.; Rainville, P.; Caron, J. G.; Pageaux, B.
10.1101/2021.12.23.474027 — neuroscience — Posted on 2021-12-24
497 Enhanced learning and sensory salience in a cerebellar mouse autism model
Oostland, M.; Kislin, M.; Chen, Y.; Chen, T.; Venditto, S. J.; Deverett, B.; Wang, S. S.- H.
10.1101/2021.12.23.474034 — neuroscience — Posted on 2021-12-24
498 A personalizable autonomous neural mass model of epileptic seizures
Lopez-Sola, E.; Sanchez-Todo, R.; Lleal, E.; Köksal-Ersöz, E.; Yochum, M.; Makhalova, J.; Mercadal, B.; Salvador, R.; Lozano-Soldevilla, D.; Modolo, J.; Bartolomei, F.; Wendling, F.; Benquet, P.; Ruffini, G.
10.1101/2021.12.24.474090 — neuroscience — Posted on 2021-12-24
500 Multiplex, translaminar imaging in the spinal cord of behaving mice
Shekhtmeyster, P.; Carey, E. M.; Duarte, D.; Ngo, A.; Gao, G.; Nelson, N. A.; Clark, C. L.; Nimmerjahn, A.
10.1101/2021.12.23.474039 — neuroscience — Posted on 2021-12-24
504 HSFA1 proteins mediate heat-induced accumulation of CPT7-derived polyprenols affecting thylakoid organization
Buszewicz, D.; Kowalewska, Łucja M.; Mazur, R.; Zajbt-Łuczniewska, M.; Surmacz, L.; Sosnowska, K.; Welc, R.; Jemioła-Rzeminska, M.; Link-Lenczowski, P.; Onysk, A.; Skorupinska-Tudek, K.; Liu, H.-C.; Charng, Y.-Y.; Archacki, R.; Gruszecki, W. I.; Swiezewska, E.
10.1101/2021.12.22.473876 — plant biology — Posted on 2021-12-24
505 Characterization of wheat lacking B-type starch granules
Saccomanno, B.; Berbezy, P.; Findlay, K.; Shoesmith, J.; Uauy, C.; Viallis, B.; Trafford, K.
10.1101/2021.10.01.462759 — plant biology — Posted on 2021-12-24
507 Metal transporter SLC39A14/ZIP14 modulates regulation between the gut microbiome and host metabolism
Thorn, T. L.; Mitchell, S. B.; Kim, Y.; Lee, M.-T.; Comrie, J. M. C.; Johnson, E. L.; Aydemir, T. B.
10.1101/2021.12.22.473859 — physiology — Posted on 2021-12-24
511 Anticancer immunotherapies transition postcapillary venules into high-endothelial venules that generate TCF1+ T lymphocyte niches through a feed-forward loop
Hua, Y.; Vella, G.; Rambow, F.; Allen, E.; Martinez, A. A.; Duhamel, M.; Junius, S.; Smeets, A.; Nittner, D.; Laoui, D.; Dimmeler, S.; Hehlgans, T.; Liston, A.; Floris, G.; Lambrechts, D.; Merchiers, P.; Bosisio, F. M.; Marine, J.-C.; Schlenner, S.; Bergers, G.
10.1101/2021.12.24.474088 — cancer biology — Posted on 2021-12-24
514 A DNA-based optical force sensor for live-cell applications
Jayachandran, C.; Ghosh, A.; Prabhune, M.; Bath, J.; Turberfield, A. J.; Hauke, L.; Enderlein, J.; Rehfeldt, F.; Schmidt, C. F.
10.1101/2021.12.21.473677 — biophysics — Posted on 2021-12-24
516 GenOtoScope: Towards automating ACMG classification of variants associated with congenital hearing loss
Melidis, D.; Landgraf, C.; Schoener-Heinisch, A.; Schmidt, G.; von Hardenberg, S.; Lesinski-Schiedat, A.; Auber, B.; Nejdl, W.
10.1101/2021.12.23.474074 — bioinformatics — Posted on 2021-12-24
517 A Combined Evidence Approach to Prioritize Nipah Virus Inhibitors
Bhardwaj, A.; Sharma, N.; Upadhyay, A.; Kalia, K.; Kumar, R.; Tuteja, K.; Paul, P. R.; Covernton, E.; Sharma, T.; Scaria, V.
10.1101/2020.03.12.977918 — bioinformatics — Posted on 2021-12-24
520 Homogeneity of antibody-drug conjugates critically impacts the therapeutic efficacy in brain tumors
Anami, Y.; Otani, Y.; Xiong, W.; Ha, S. Y. Y.; Yamaguchi, A.; Zhang, N.; An, Z.; Kaur, B.; Tsuchikama, K.
10.1101/2021.12.23.474044 — bioengineering — Posted on 2021-12-24
528 Profiling the Landscape of Drug Resistance Mutations in Neosubstrates to Molecular Glue Degraders
Gosavi, P. M.; Ngan, K. C.; Yeo, M.; Su, C.; Li, J.; Lue, N. Z.; Hoenig, S. M.; Liau, B. B.
10.1101/2021.12.23.474016 — molecular biology — Posted on 2021-12-24
529 Litter commensal bacteria can limit the horizontal gene transfer of antimicrobial resistance to Salmonella in chickens
Oladeinde, A.; Abdo, Z.; Zwirzitz, B.; Woyda, R.; Lakin, S. M.; Press, M. O.; Cox, N. A.; Thomas, J. C.; Looft, T. P.; Rothrock, M. J.; Zock, G.; Plumblee Lawrence, J.; Cudnik, D.; Ritz, C.; Aggrey, S. E.; Liachko, I.; Grove, J.; Wiersma, C.
10.1101/2021.04.02.438293 — microbiology — Posted on 2021-12-24
533 Trans-segmental imaging in the spinal cord of behaving mice
Shekhtmeyster, P.; Duarte, D.; Carey, E. M.; Ngo, A.; Gao, G.; Olmstead, J. A.; Nelson, N. A.; Nimmerjahn, A.
10.1101/2021.12.23.474042 — neuroscience — Posted on 2021-12-24
535 Do Motoneurons Slow With Aging? A Systematic Review And Meta-Analysis With Meta-Regression
Orssatto, L. B. R.; Borg, D.; Pendrith, L.; Shield, A. J.; Blazevich, A. J.; Trajano, G. S.
10.1101/2020.12.15.422812 — physiology — Posted on 2021-12-24
539 Production and characterization of virus-free, CRISPR-CAR T cells capable of inducing solid tumor regression
Mueller, K.; Piscopo, N.; Forsberg, M.; Saraspe, L.; Das, A.; Russell, B.; Smerchansky, M.; Shi, L.; Shankar, K.; Ali, A.; Lazzarotto, C.; Tsai, S.; Capitini, C. M.; Saha, K.
10.1101/2021.08.06.455489 — bioengineering — Posted on 2021-12-24
540 TIAToolbox: An End-to-End Toolbox for Advanced Tissue Image Analytics
Pocock, J.; Graham, S.; Vu, Q. D.; Jahanifar, M.; Deshpande, S.; Hadjigeorghiou, G.; Shephard, A.; Bashir, R. M. S.; Bilal, M.; Lu, W.; Epstein, D.; Minhas, F.; Rajpoot, N.; Raza, S. E. A.
10.1101/2021.12.23.474029 — bioengineering — Posted on 2021-12-24
542 An empirical evaluation of genotype imputation of ancient DNA
Ausmees, K.; Sanchez-Quinto, F.; Jakobsson, M.; Nettelblad, C.
10.1101/2021.12.22.473913 — genomics — Posted on 2021-12-24
543 Spatiotemporal transcriptomics reveals pathogenesis of viral myocarditis
Mantri, M.; Hinchman, M. M.; McKellar, D. W.; Wang, M. F. Z.; Cross, S. T.; Parker, J. S. L.; De Vlaminck, I.
10.1101/2021.12.07.471659 — genomics — Posted on 2021-12-24
544 Epistatic selection on a selfish Segregation Distorter supergene: drive, recombination, and genetic load
Navarro-Dominguez, B.; Chang, C.-H.; Brand, C.; Muirhead, C.; Presgraves, D.; Larracuente, A. M.
10.1101/2021.12.22.473781 — evolutionary biology — Posted on 2021-12-24
545 PMRT1, a Plasmodium specific parasite plasma membrane transporter is essential for asexual and sexual blood stage development
Wichers, J. S.; Mesen-Ramirez, P.; Yu-Strzelczyk, J.; Fuchs, G.; Stäcker, J.; von Thien, H.; Alder, A.; Henshall, I.; Liffner, B.; Nagel, G.; Löw, C.; Wilson, D. W.; Spielmann, T.; Gao, S.; Gilberger, T.; Bachmann, A.; Strauss, J.
10.1101/2021.12.21.473770 — molecular biology — Posted on 2021-12-24
546 XAB2 Dynamics during DNA Damage-Dependent Transcription Inhibition
DONNIO, L.-M.; Cerutti, E.; Magnani, C.; Neuillet, D.; Mari, P.-O.; Giglia-Mari, G.
10.1101/2021.12.23.473962 — molecular biology — Posted on 2021-12-24
547 Regulation of KHNYN antiviral activity by the extended di-KH domain and nucleo-cytoplasmic trafficking
Lista, M. J.; Galao, R. P.; Ficarelli, M.; Kmiec, D.; Wilson, H.; Winstone, H.; Morris, E. R.; Mischo, H. E.; Wanford, J.; Youle, R.; Odendall, C.; Taylor, I. A.; Neil, S. J.; Swanson, C.
10.1101/2021.12.22.473955 — microbiology — Posted on 2021-12-24
548 Bionized nanoferrite particles alter the course of experimental Cryptococcus neoformans pneumonia
Liporagi Lopes, L. C.; Korangath, P.; dos Santos Junior, S. R.; Gabrielson, K. L.; Ivkov, R.; Casadevall, A.
10.1101/2021.12.21.473767 — microbiology — Posted on 2021-12-24
549 Combination of Mycobacterium tuberculosis RS ratio and CFU improves the ability of murine efficacy experiments to distinguish between drug treatments
Dide-Agossou, C.; Bauman, A. A.; Ramey, M. E.; Rossmassler, K.; Al Mubarak, R.; Pauly, S.; Voskuil, M. I.; Garcia?Cremades, M.; Savic, R. M.; Nahid, P.; Moore, C. M.; Tasneen, R.; Nuermburger, E.; Robertson, G. T.; Walter, N. D.
10.1101/2021.12.21.473768 — microbiology — Posted on 2021-12-24
550 Hypersensitivity to uncertainty is key feature of subjective cognitive impairment
Attaallah, B.; Petitet, P.; Slavkova, E.; Turner, V.; Saleh, Y.; Manohar, S. G.; Husain, M.
10.1101/2021.12.23.473986 — neuroscience — Posted on 2021-12-24
554 A spatiotemporal steroidogenic regulatory network in human fetal adrenal glands and gonads
Wang, Y.; Guo, B.; Guo, Y.; Qi, N.; Lv, Y.; Ye, Y.; Huang, Y.; Long, X.; Chen, H.; Su, C.; Zhang, L.; Zhang, Q.; Li, M.; Liao, J.; Yan, Y.; Mao, X.; zeng, y.; Jiang, J.; Chen, Z.; Guo, Y.; Gao, S.; cheng, j.; Jiang, Y.; Mo, Z.
10.1101/2021.12.22.473776 — systems biology — Posted on 2021-12-24
558 Control effectiveness of APL formulation against dengue- and Zika-transmitting Aedes mosquitoes in Gia Lai province, Vietnam
Hue, P. T. K.; Vien, L. T.; Nga, D. M.; Truong, L. V.; Ha, H.; Khoa, P. T.; Nhung, L. T.; Hieu, H. V.; Sy, L. D.; Trung, T. N.; Quang, T. T. D. T. U. D. H. D. T.; Loc, T. V.
10.1101/2021.12.22.473821 — biochemistry — Posted on 2021-12-24
561 Reciprocal interactions between the gut microbiome and mammary tissue mast cells promote metastatic dissemination of HR+ breast tumors
Feng, T.-Y.; Azar, F. N.; Rosean, C. B.; McGinty, M. T.; Putelo, A. M.; Koli, S.; Marino, N.; German, R.; Podicheti, R.; Dreger, S. A.; Fowler, W. J.; Greenfield, S.; Robinson, S. D.; Rutkowski, M. R.
10.1101/2021.12.23.474065 — cancer biology — Posted on 2021-12-24
565 Novel allosteric mechanism of dual p53/MDM2 and p53/MDM4 inhibition by a small molecule
Grinkevich, V.; Aparna, V.; Fawkner, K.; Issaeva, N.; Andreotti, V.; Dickinson, E. R.; Hedstrom, E.; Spinnler, C.; Inga, A.; Larsson, L.-G.; Karlen, A.; Wilhelm, M.; Barran, P.; Okorokov, A.; Selivanova, G.; Zawacka-Pankau, J. E.
10.1101/2021.12.24.474003 — biochemistry — Posted on 2021-12-24
569 The cardiac lncRNA Chantico directly regulates Cxcl1 chemokine transcription
Hall, J. M.; Kainth, A. S.; Rowton, M. J.; Lu, E.; Haddad, G.; Keplinger, A. J.; Scepanovic, J.; Perez-Cervantes, C.; Chan, S. S. K.; Piccirilli, J. A.; Moskowitz, I. P.; Ruthenburg, A. J.
10.1101/2021.12.23.474040 — molecular biology — Posted on 2021-12-24
570 Metabolic regulation by prostaglandin E2 impairs lung group 2 innate lymphoid cell responses
Robb, C.; Zhou, Y.; Felton, J.; Zhang, B.; Goepp, M.; Jheeta, P.; Smyth, D.; Breyer, R.; Narumiya, S.; McSorley, H.; Maizels, R.; Schwarze, J.; Rossi, A.; Yao, C.
10.1101/2021.12.23.474031 — immunology — Posted on 2021-12-24
571 Age related susceptibility to grey matter demyelination and neurodegeneration is associated with meningeal neutrophil accumulation in an animal model of Multiple Sclerosis
Zuo, M.; Fettig, N.; Bernier, L.-P.; Possnecker, E.; Spring, S.; Pu, A.; Ma, X. I.; Lee, D. S.; Ward, L.; Sharma, A.; Kuhle, J.; Sled, J. G.; Probstel, A.-K.; MacVicar, B. A.; Osborne, L. C.; Gommerman, J. L.; Ramaglia, V.
10.1101/2021.12.23.474008 — immunology — Posted on 2021-12-24
574 Astroglial CD38 regulates social memory and synapse formation through SPARCL1 in the medial prefrontal cortex
HATTORI, T.; Cherepanov, S. M.; Sakaga, R.; Roboon, J.; Nguyen, D. T.; Ishii, H.; Takarada-Iemata, M.; Nishiuchi, T.; Kannon, T.; Hosomichi, K.; Tajima, A.; Yamamoto, Y.; Okamoto, H.; Sugawara, A.; Higashida, H.; Hori, O.
10.1101/2021.12.23.474051 — neuroscience — Posted on 2021-12-24
575 TACAN is a novel regulator of PKD2
Liu, X.; Zhang, R.; Fatehi, M.; Wang, Y.; Long, W.; Tian, R.; Deng, X.; Weng, Z.; Xu, Q.; Light, P. E.; Tang, J.; Chen, X.-Z.
10.1101/2021.12.23.473878 — physiology — Posted on 2021-12-24
577 Neurons burdened by DNA double strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration.
Welch, G. M.; Boix, C. A.; Schmauch, E.; Davila-Velderrain, J.; Victor, M. B.; Dileep, V.; Bozzelli, L.; Cheng, J. D.; Lee, A.; Lee, A.; Su, Q.; Pfenning, A. R.; Kellis, M.; Tsai, L.-H.
10.1101/2021.12.23.474002 — neuroscience — Posted on 2021-12-23
583 Directing Min protein patterns with advective bulk flow
Meindlhumer, S.; Brauns, F.; Finzgar, J. R.; Kerssemakers, J.; Dekker, C.; Frey, E.
10.1101/2021.12.23.474007 — biophysics — Posted on 2021-12-23
585 Computational Mapping of the Human-SARS-CoV-2 Protein-RNA Interactome
Horlacher, M.; Oleshko, S.; Hu, Y.; Ghanbari, M.; Vergara, E. E.; Mueller, N.; Ohler, U.; Moyon, L.; Marsico, A.
10.1101/2021.12.22.472458 — bioinformatics — Posted on 2021-12-23
587 Rapid longitudinal SARS-CoV-2 intra-host emergence of novel haplotypes regardless of immune deficiencies
Manuto, L.; Grazioli, M.; Spitaleri, A.; Fontana, P.; Bianco, L.; Bertolotti, L.; Bado, M.; Mazzotti, G.; Bianca, F.; Onelia, F.; Lorenzin, G.; Simeoni, F.; Lazarevic, D.; Franchin, E.; Del Vecchio, C.; Dorigatti, I.; Tonon, G.; Cirillo, d.; Lavezzo, E.; Crisanti, A.; Toppo, S.
10.1101/2021.12.22.473949 — evolutionary biology — Posted on 2021-12-23
588 Protein homeostasis is maintained by proteasomes containing PSMB9 induced by EEF1A2 upon mitochondrial stress
Kim, M.; Samluk, L.; Stepkowski, T. M.; Suppanz, I.; Serwa, R. A.; Kodron, A.; Warscheid, B.; Chacinska, A.
10.1101/2021.12.23.473808 — cell biology — Posted on 2021-12-23
589 SARS-CoV-2 Omicron Spike recognition by plasma from individuals receiving BNT162b2 mRNA vaccination with a 16-weeks interval between doses
Chatterjee, D.; Tauzin, A.; Marchitto, L.; Gong, S. Y.; Boutin, M.; Bourassa, C.; Beaudoin-Bussieres, G.; Bo, Y.; Ding, S.; Laumaea, A.; Vezina, D.; Perreault, J.; Gokool, L.; Morrisseau, C.; Arlotto, P.; Fournier, E.; Guilbault, A.; Delisle, B.; Levade, I.; Goyette, G.; Gendron-Lepage, G.; Medjahed, H.; De Serres, G.; Tremblay, C.; Martel-Laferriere, V.; Kaufmann, D. E.; Bazin, R.; Prevost, J.; Moreira, S.; Richard, J.; Cote, M.; Finzi, A.
10.1101/2021.12.21.473679 — microbiology — Posted on 2021-12-23
590 SARS-CoV-2 Omicron neutralization by therapeutic antibodies, convalescent sera, and post-mRNA vaccine booster
Lusvarghi, S.; Pollett, S. D.; Neerukonda, S. N.; WANG, W.; Wang, R.; Vassell, R.; Epsi, N. J.; Fries, A. C.; Agan, B. K.; Lindholm, D. A.; Lalani, T.; Mody, R.; Ewers, E. C.; Lalani, T.; Ganesan, A.; Goguet, E.; Hollis-Perry, M.; Coggins, S. A.; Simons, M. P.; Katzelnick, L. C.; Wang, G.; Broder, C. C.; Tribble, D. R.; Bentley, L. M.; Eakin, A. E.; Erlandson, K. J.; Laing, E. D.; Burgess, T. H.; Mitre, E.; Weiss, C. D.
10.1101/2021.12.22.473880 — microbiology — Posted on 2021-12-23
591 Engineered ACE2 counteracts vaccine-evading SARS-CoV-2 Omicron variant
Ikemura, N.; Taminishi, S.; Inaba, T.; Arimori, T.; Motooka, D.; Katoh, K.; Kirita, Y.; Kirita, Y.; Li, S.; Itoh, Y.; Ozaki, Y.; Nakamura, S.; Matoba, S.; Standley, D. M.; Okamoto, T.; Takagi, J.; Hoshino, A.
10.1101/2021.12.22.473804 — microbiology — Posted on 2021-12-23
592 Interferon-induced transmembrane protein 3 (IFITM3) limits lethality of SARS-CoV-2 in mice
Zani, A.; Kenney, A.; Kawahara, J.; Eddy, A. C.; Wang, X.-L.; KC, M.; Lu, M.; Hemann, E. A.; Li, J.; Peeples, M. E.; Hall-Stoodley, L.; Forero, A.; Cai, C.; Ma, J.; Yount, J. S.
10.1101/2021.12.22.473914 — immunology — Posted on 2021-12-23
594 Waning immune responses against SARS-CoV-2 among vaccinees in Hong Kong
Peng, Q.; Zhou, R.; Wang, Y.; Zhao, M.; Liu, N.; Li, S.; Huang, H.; Yang, D.; Au, K.-K.; Wang, H.; Man, K.; Yuen, K.-Y.; Chen, Z.
10.1101/2021.12.22.473934 — immunology — Posted on 2021-12-23
595 Accelerating manufacturing to start large-scale supply of a new adenovirus-vectored vaccine within 100 days
Joe, C. C.; Segireddy, R. R.; Oliveira, C.; Berg, A.; Li, Y.; Doultsinos, D.; Chopra, N.; Scholze, S.; Ahmad, A.; Nestola, P.; Niemann, J.; Douglas, A.
10.1101/2021.12.22.473478 — bioengineering — Posted on 2021-12-23
598 High-throughput UHPLC-MS to screen metabolites in feces for gut metabolic health
Zawadzki, A. d.; Thiele, M.; Suvitaival, T.; Wretlind, A.; Kim, M.; Ali, M.; Bjerre, A. F.; Stahr, K.; Mattila, I.; Hansen, T.; Krag, A.; Legido-Quigley, C.
10.1101/2021.12.22.473790 — biochemistry — Posted on 2021-12-23
600 Influential factors of saliva microbiota composition
Wells, P. M.; Sprockett, D. D.; Bowyer, R. C.; Kurushima, Y.; Williams, F. M.; Relman, D.; Steves, C. J.
10.1101/2021.12.22.473816 — microbiology — Posted on 2021-12-23
601 Single-domain antibodies efficiently neutralize SARS-CoV-2 variants of concern, including Omicron variant
Favorskaya, I. A.; Shcheblyakov, D. V.; Esmagambetov, I. B.; Dolzhikova, I. V.; Alekseeva, I. A.; Korobkova, A. I.; Voronina, D. V.; Ryabova, E. I.; Derkaev, A. A.; Kovyrshina, A. V.; Iliukhina, A. A.; Botikov, A. G.; Voronina, O. L.; Egorova, D. A.; Zubkova, O. V.; Ryzhova, N. N.; Aksenova, E. I.; Kunda, M. S.; Logunov, D. Y.; Naroditsky, B. S.; Gintsburg, A. L.
10.1101/2021.11.24.469842 — immunology — Posted on 2021-12-23
604 Sexual and individual signatures are encoded in the temporal rate of Cape gannet display calls
Bowmaker-Falconer, K.; Thiebault, A.; Connan, M.; Aubin, T.; Charrier, I.; Pistorius, P.
10.1101/2021.12.23.473090 — zoology — Posted on 2021-12-23
605 Photosynthetic light harvesting and thylakoid organization in a CRISPR/Cas9 Arabidopsis thaliana LHCB1 knockout mutant.
Vayghan, H. S.; Nawrocki, W. J.; Schiphorst, C.; Tolleter, D.; Chen, H.; Douet, V.; Glauser, G.; Finazzi, G.; Croce, R.; Wientjes, E.; Longoni, F.
10.1101/2021.12.22.473855 — plant biology — Posted on 2021-12-23
607 Baltica: integrated splice junction usage analysis
Britto-Borges, T.; Boehm, V.; Gehring, N. H.; Dieterich, C.
10.1101/2021.12.23.473966 — bioinformatics — Posted on 2021-12-23
609 New cell biological explanations for kinesin-linked axon degeneration
Liew, Y.-T.; Voelzmann, A.; Pinho-Correia, L. M.; Murphy, T.; Tortoishell, H.; Parkin, J.; Bailey, D. M. D.; Landgraf, M.; Prokop, A.
10.1101/2021.12.23.473961 — cell biology — Posted on 2021-12-23
610 Efficacy of antiviral drugs against the omicron variant of SARS-CoV-2.
Dabrowska, A.; Szczepanski, A.; Botwina, P.; Mazur-Panasiuk, N.; Jirincova, H.; Rabalski, L.; Zajic, T.; Popowicz, G.; Pyrc, K.
10.1101/2021.12.21.473268 — microbiology — Posted on 2021-12-23
614 Subject-specific features of excitation/inhibition profiles in neurodegenerative diseases
Monteverdi, A.; Palesi, F.; Costa, A.; Vitali, P.; Pichiecchio, A.; Cotta Ramusino, M.; Bernini, S.; Jirsa, V.; Gandini Wheeler-Kingshott, C. A. M.; D'Angelo, E.
10.1101/2021.12.23.473997 — neuroscience — Posted on 2021-12-23
617 Optimizing a High Performing Multiplex-CRISPRi P. putida strain with Integrated Metabolomics and 13C-Metabolic Flux Analyses
Czajka, J. J.; Banerjee, D.; Eng, T. T.; Menasalvas, J.; Yan, C.; Munoz Munoz, N.; Poirier, B. C.; Kim, Y.-M.; Baker, S. E.; Tang, Y. J.; Mukhopadhyay, A.
10.1101/2021.12.23.473729 — synthetic biology — Posted on 2021-12-23
618 Transport receptor occupancy in Nuclear Pore Complex mimics
Fragasso, A.; de Vries, H. W.; Andersson, J.; van der Sluis, E. O.; van der Giessen, E.; Onck, P.; Dekker, C.
10.1101/2021.12.22.473839 — biophysics — Posted on 2021-12-23
621 Adjustment for SNPs instead of demographic and clinical covariates in GWAS
Xue, F.; Sun, X.; Li, H.; Yu, Y.; Yuan, Z.; Jin, C.; Hou, L.; Liu, X.; Wang, Q.
10.1101/2021.12.22.473912 — genetics — Posted on 2021-12-23
625 A single-cell atlas of human fetal lung development between 14 and 19 weeks of gestation
Renesme, L.; Lesage, F.; Cook, D.; Zhong, S.; Hanninen, S. M.; Carpen, O.; Mizikova, I.; Thebaud, B.
10.1101/2021.12.23.473945 — developmental biology — Posted on 2021-12-23
626 Effects of α-crystallin gene knockout on zebrafish lens development
Posner, M.; Murray, K. L.; Andrew, B.; Brdicka, S.; Butterbaugh-Roberts, A.; Franklin, K.; Hussen, A.; Kaye, T.; Kepp, E.; McDonald, M.; Snodgrass, T.; Zientek, K.; David, L.
10.1101/2021.12.22.473921 — developmental biology — Posted on 2021-12-23
628 Nucleocapsid 203 mutations enhance SARS-CoV-2 immune evasion
Lin, X.; Xue, W.; Zhang, Y.; Fu, B.; Trimpert, J.; Xing, N.; Kunec, D.; Tang, W.; Xiao, Y.; Meng, K.; Shi, S.; Wu, H.; Meng, G.; Zhu, Z.
10.1101/2021.12.20.473471 — microbiology — Posted on 2021-12-23
629 Construction of a potent pan-vaccine based on the evolutionary tendency of SARS-CoV-2 spike protein.
Zhao, Y.; Ni, W.; Liang, S.; Dong, L.; Xiang, M.; Cai, Z.; Niu, D.; Zhang, Q.; Wang, D.; Zheng, Y.; Zhang, Z.; Zhou, D.; Guo, W.; Pan, Y.; Wu, X.; Yang, Y.; Jing, Z.; Jiang, Y.; SARS-CoV-2 Vaccine Task Force Group, ; Chen, Y.; Yan, H.; Zhou, Y.; Xu, K.; Lan, K.
10.1101/2021.12.21.473594 — microbiology — Posted on 2021-12-23
630 MAVS mediates a protective immune response in the brain to Rift Valley fever virus
Weilhammer, D. R.; Hum, N. R.; Bourguet, F. A.; Sebastian, A.; Lam, D.; Phillips, A. M.; Sanchez, K. R.; Rasley, A.; Loots, G. G.
10.1101/2021.12.22.473954 — immunology — Posted on 2021-12-23
632 Anti-SARS-CoV-2 human antibodies retaining neutralizing activity against SARS-CoV-2 B.1.1.529 (omicron)
Imbrechts, M.; Kerstens, W.; Rasulova, M.; Vercruysse, T.; Maes, W.; Ampofo, L.; Ven, K.; Lammertyn, J.; Vanhoorelbeke, K.; Callewaert, N.; Neyts, J.; Dallmeier, K.; Declerck, P.; Thibaut, H. J.; Geukens, N.
10.1101/2021.12.21.473706 — immunology — Posted on 2021-12-23
633 Structural basis for antibody resistance to SARS-CoV-2 omicron variant
Cerutti, G.; Guo, Y.; Lihong, L.; Zhang, Z.; Liu, L.; Luo, Y.; Huang, Y.; Wang, H. H.; Ho, D. D.; Sheng, Z.; Shapiro, L.
10.1101/2021.12.21.473620 — immunology — Posted on 2021-12-23
636 Dual Passive Reactive Brain Computer Interface: a Novel Approach to Human-Machine Symbiosis
Dehais, F.; Ladouce, S.; Darmet, L.; Nong, T.-V.; Ferraro, G.; Torre Tresols, J.; Velut, S.; Labedan, P.
10.1101/2021.12.23.473161 — neuroscience — Posted on 2021-12-23
638 Multimodal lesion network mapping to predict sensorimotor behavior in stroke patients
Jimenez-Marin, A.; De Bruyn, N.; Gooijers, J.; Llera, A.; Meyer, S.; Alaerts, K.; Verheyden, G.; Swinnen, S. P.; Cortes, J. M.
10.1101/2021.12.23.473973 — neuroscience — Posted on 2021-12-23
639 Remote contextual fear retrieval engages activity from salience network regions in rats
dos Santos Correa, M.; Grisanti, G. D. V.; Franciscatto, I. A. F.; Tarumoto, T. S. A.; Tiba, P. A.; Ferreira, T. L.; Fornari, R. V.
10.1101/2021.12.22.473939 — neuroscience — Posted on 2021-12-23
642 A synthetic membrane shaper for controlled liposome deformation
De Franceschi, N.; Pezeshkian, W.; Fragasso, A.; Bruininks, B.; Tsai, S.; Marrink, S.-J.; Dekker, C.
10.1101/2021.12.22.473854 — synthetic biology — Posted on 2021-12-23
644 Lack of pulmonary fibrogenicity and carcinogenicity of titanium dioxide nanoparticles in 26-week inhalation study in rasH2 mouse model
Yamano, S.; Takeda, T.; Goto, Y.; Hirai, S.; Furukawa, Y.; Kikuchi, Y.; Kasai, T.; Misumi, K.; Suzuki, M.; Takanobu, K.; Senoh, H.; Saito, M.; Kondo, H.; Umeda, Y.
10.1101/2021.12.23.473959 — pharmacology and toxicology — Posted on 2021-12-23
645 Comparative assessment of electronic nicotine delivery systems aerosol and cigarette smoke on endothelial cell migration: the Replica Project
Caruso, M.; Emma, R.; Distefano, A.; Rust, S.; Poulas, K.; Giordano, A.; Volarevic, V.; Mesiakaris, K.; Boffo, S.; Arsenijevic, A.; Karanasios, G.; Pulvirenti, R.; Ilic, A.; Canciello, A.; Zuccarello, P.; Ferrante, M.; Polosa, R.; Li Volti, G.
10.1101/2021.12.23.473979 — pharmacology and toxicology — Posted on 2021-12-23
652 The Need for Transfer Learning in CRISPR-Cas Off-Target Scoring
Kota, P. K.; Pan, Y.; Vu, H.-A.; Cao, M.; Baraniuk, R. G.; Bao, G.
10.1101/2021.08.28.457846 — bioinformatics — Posted on 2021-12-23
653 Stain-free nucleus identification in holographic learning flow cyto-tomography
Pirone, D.; Lim, J.; Merola, F.; Miccio, L.; Mugnano, M.; Bianco, V.; Cimmino, F.; Visconte, F.; Montella, A.; Capasso, M.; Iolascon, A.; Memmolo, P.; Psaltis, D.; Ferraro, P.
10.1101/2021.12.22.473826 — bioengineering — Posted on 2021-12-23
655 Functional design of bacterial superoxide:quinone oxidoreductase
von Ballmoos, C.; Abou-Hamdan, A.; Mahler, R.; Grossenbacher, P.; Biner, O.; Sjöstrand, D.; Lochner, M.; Högbom, M.
10.1101/2021.12.23.473985 — biochemistry — Posted on 2021-12-23
656 Epilipidomics platform for holistic profiling of oxidized complex lipids in blood plasma of obese individuals
Criscuolo, A.; Nepachalovich, P.; Garcia-del Rio, D. F.; Lange, M.; Ni, Z.; Blueher, M.; Fedorova, M.
10.1101/2021.12.23.473968 — biochemistry — Posted on 2021-12-23
659 Dead infant carrying by chimpanzee mothers in the Budongo Forest
Soldati, A.; Fedurek, P.; Crockford, C.; Adue, S.; Akankwasa, J. W.; Asiimwe, C.; Asua, J.; Atayo, G.; Chandia, B.; Freymann, E.; Fryns, C.; Muhumuza, G.; Taylor, D.; Zuberbuhler, K.; Hobaiter, C.
10.1101/2021.12.22.473786 — animal behavior and cognition — Posted on 2021-12-23
660 The first sheep graph pan-genome reveals the spectrum of structural variations and their effects on different tail phenotypes
Li, R.; Gong, M.; Zhang, X.; Wang, F.; Liu, Z.; Zhang, L.; Xu, M.; Zhang, Y.; Dai, X.; Zhang, Z.; Fang, W.; Yang, Y.; Zhang, H.; Fu, W.; Cao, C.; Yang, P.; Ghanatsaman, Z. A.; Negari, N. J.; Nanaei, H. A.; Yue, X.; Song, Y.; Lan, X.; Deng, W.; Wang, X.; Xiang, R.; Ibeagha-Awemu, E. M.; Heslop-Harrison, P.; Lenstra, J. A.; Gan, S.; Jiang, Y.
10.1101/2021.12.22.472709 — genomics — Posted on 2021-12-23
661 Heterogeneity and genomic loci of ubiquitous Cre reporter transgenes in zebrafish
Lalonde, R. L.; Kemmler, C. L.; Riemslagh, F. W.; Aman, A. J.; Kresoja-Rakic, J.; Moran, H. R.; Nieuwenhuize, S.; Parichy, D. M.; Burger, A.; Mosimann, C.
10.1101/2021.12.22.473906 — genetics — Posted on 2021-12-23
662 The antique genetic plight of the Mediterranean monk seal (Monachus monachus)
Salmona, J.; Dayon, J.; Lecompte, E.; Karamanlidis, A. A.; Aguilar, A.; Fernandez de Larrinoa, P.; Pires, R.; Mo, G.; Agnesi, A.; Borrell, A.; Danyer, E.; Öztürk, B.; Tonay, A. M.; Gonzalez, L. M.; Dendrinos, P.; Gaubert, P.
10.1101/2021.12.23.473149 — genetics — Posted on 2021-12-23
663 A novel zebrafish model of SPEG-related centronuclear myopathy (CNM): characterization and comparison with other CNM model zebrafish
Espinosa, K. G.; Geissah, S.; Groom, L.; Volpatti, J.; Scott, I. C.; Dirksen, R. T.; Zhao, M.; Dowling, J. J.
10.1101/2021.12.22.473918 — genetics — Posted on 2021-12-23
664 Recombination suppression and selection affect local ancestries in genomes of a migratory songbird
Ishigohoka, J.; Bascon-Cardozo, K.; Bours, A.; Fuss, J.; Rhie, A.; Mountcastle, J.; Haase, B.; Chow, W.; Collins, J.; Howe, K.; Uliano-Silva, M.; Fedrigo, O.; Jarvis, E. D.; Perez-Tris, J.; Illera, J. C.; Liedvogel, M.
10.1101/2021.12.22.473882 — evolutionary biology — Posted on 2021-12-23
666 Treated like dirt: Robust forensic and ecological inferences from soil eDNA after challenging sample storage
Froslev, T. G.; Ejrnaes, R.; Hansen, A. J.; Bruun, H. H.; Nielsen, I. B.; Ekelund, F.; Vestergard, M.; Kjoller, R.
10.1101/2021.12.22.473824 — ecology — Posted on 2021-12-23
671 Blue and green food webs respond differently to elevation and land use
Ho, H.-C.; Brodersen, J.; Gossner, M. M.; Graham, C. H.; Kaeser, S.; Reji Chacko, M.; Seehausen, O.; Zimmermann, N. E.; Pellissier, L.; Altermatt, F.
10.1101/2021.12.22.473785 — ecology — Posted on 2021-12-23
672 Continental-scale Hyperspectral tree species classification in the National Ecological Observatory Network
Marconi, S.; Weinstein, B. G.; Zou, S.; Bohlman, S. A.; Zare, A.; Singh, A.; Stewart, D.; Harmon, I.; Steinkraus, A.; White, E. P.
10.1101/2021.12.22.473714 — ecology — Posted on 2021-12-23
673 Liquid-liquid phase separation facilitates the biogenesis of secretory storage granules
PARCHURE, A.; Tian, M.; Boyer, C. K.; Bearrows, S. C.; Rohli, K. E.; Zhang, J.; Ramazanov, B. R.; Wang, Y.; Stephens, S.; von Blume, J.
10.1101/2021.12.22.472607 — cell biology — Posted on 2021-12-23
674 High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effect
Tong, H.; Huang, J.; Xiao, Q.; He, B.; Dong, X.; Liu, Y.; Yang, X.; Han, D.; Wang, Z.; Ying, W.; Zhang, R.; Wei, Y.; Wang, X.; Xu, C.; Zhou, Y.; Li, Y.; Cai, M.; Wang, Q.; Xue, M.; Li, G.; Fang, K.; Zhang, H.; Yang, H.
10.1101/2021.12.18.473271 — molecular biology — Posted on 2021-12-23
675 Intramolecular interactions enhance the potency of gallinamide A analogs against Trypanosoma cruzi
Da Silva, E. B.; Sharma, V.; Hernandez-Alvarez, L.; Tang, A. H.; Stoye, A.; O'Donoghue, A. J.; Gerwick, W. H.; Payne, R. J.; McKerrow, J. H.; Podust, L. M.
10.1101/2021.12.22.473926 — molecular biology — Posted on 2021-12-23
677 Coupled protein quality control during nonsense mediated mRNA decay
Inglis, A. J.; Guna, A.; Merchan, A. G.; Pal, A.; Esantsi, T. K.; Keys, H. R.; Frenkel, E. M.; Oania, R.; Weissman, J. S.; Voorhees, R. M.
10.1101/2021.12.22.473893 — molecular biology — Posted on 2021-12-23
678 Copper Acts Synergistically with Fluconazole in Candida glabrata by Compromising Drug Efflux, Sterol Metabolism, and Zinc Homeostasis
Gaspar-Cordeiro, A.; Amaral, C.; Pobre, V.; Antunes, W.; Petronilho, A.; Paixao, P.; Alves de Matos, A. P.; Pimentel, C.
10.1101/2021.12.22.473865 — microbiology — Posted on 2021-12-23
680 Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus
Zhao, F.; Berndsen, Z. T.; Pedreno-Lopez, N.; Burns, A.; Allen, J. D.; Barman, S.; Lee, W.-H.; Chakraborty, S.; Gnanakaran, S.; Sewall, L. M.; Ozorowski, G.; Limbo, O.; Song, G.; Yong, P.; Callaghan, S.; Weisgrau, K. L.; Lifson, J. D.; Nedellec, R.; Voigt, T. B.; Laurino, F.; Louw, J.; Rosen, B. C.; Ricciardi, M.; Crispin, M.; Desrosiers, R. C.; Rakasz, E. G.; Watkins, D. I.; Andrabi, R.; Ward, A. B.; Burton, D. R.; Sok, D.
10.1101/2021.12.22.473937 — immunology — Posted on 2021-12-23
681 ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection
Ching, K. L.; de Vries, M.; Gago, J.; Dancel-Manning, K.; Sall, J.; Rice, W. J.; Barnett, C.; Liang, F.-X.; Thorpe, L. E.; Shopsin, B.; Segal, L. N.; Dittmann, M.; Torres, V. J.; Cadwell, K.
10.1101/2021.12.17.473223 — immunology — Posted on 2021-12-23
682 Transcriptome features of trained immunity in Drosophila
Fuse, N.; Okamori, C.; Tang, C.; Hirai, K.; Okaji, R.; Kurata, S.
10.1101/2021.12.22.473822 — immunology — Posted on 2021-12-23
683 Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesis
Hiller, B.; Yin, Y.; Perng, Y.-C.; de Araujo Castro, I.; Fox, L.; Locke, M.; Monte, K.; Lopez, C.; Ornitz, D.; Lenschow, D.
10.1101/2021.12.22.473953 — immunology — Posted on 2021-12-23
684 Type I Interferon Signaling Drives Microglial Dysfunction and Senescence in Human iPSC Models of Down Syndrome and Alzheimers Disease
Jin, M.; Xu, R.; Alam, M. M.; Ma, Z.; Zhu, S.; Wang, L.; Martini, A. C.; Bernabucci, M.; Xie, P.; Kwan, K.; Pang, Z. P.; Head, E.; Liu, Y.; Hart, R. P.; Jiang, P.
10.1101/2021.12.22.473858 — neuroscience — Posted on 2021-12-23
692 Taking stock of the past: A psychometric evaluation of the Autobiographical Interview
Lockrow, A. W.; Setton, R.; Spreng, K. A.; Sheldon, S.; Turner, G. R.; Spreng, R. N.
10.1101/2021.12.22.473803 — neuroscience — Posted on 2021-12-23
693 The what and where of synchronous sound perception
van Bentum, G. C.; Van Opstal, J.; van Wanrooij, M. M.
10.1101/2021.12.22.473782 — neuroscience — Posted on 2021-12-23
696 Cannabinoid during adolescence phenocopies reelin haploinsufficiency in prefrontal cortex synapses
Hurtado-Silva, T. J.; Giua, G.; Lassalle, O.; Murphy, M. N.; Wager-Miller, J.; Mackie, K.; MANZONI, O. J.; Chavis, P.
10.1101/2021.12.22.473793 — neuroscience — Posted on 2021-12-23
699 AI-driven high-throughput automation of behavioral analysis and dual-channel wireless optogenetics for multiplexing brain dynamics
Kim, W. S.; Liu, J.; Li, Q.; Hong, S.; Qi, K.; Cherukur, R.; Yoon, B.-J.; Moscarello, J.; Choe, Y.; Maren, S.; Park, S. i.
10.1101/2021.09.23.461279 — neuroscience — Posted on 2021-12-23
701 Positive supercoiling buildup is a trigger of E. coli's short-term response to cold shock
Dash, S.; Palma, C.; Baptista, I.; Bahrudeen, M.; Almeida, B.; Chauhan, V.; Jagadeesan, R.; Ribeiro, A.
10.1101/2021.12.22.473827 — systems biology — Posted on 2021-12-23
702 A systems approach discovers the role and characteristics of seven LysR type transcription factors in Escherichia coli
Rodionova, I. A.; Gao, Y.; Lim, H. G.; Saier, M. H.; Palsson, B.; Monk, J.; Rodionov, D. A.; Szubin, R.
10.1101/2021.12.22.473864 — systems biology — Posted on 2021-12-23
706 Vicia faba TPC1, a genetically encoded variant of the vacuole Two Pore Channel 1, is hyperexcitable
Lu, J.; Dreyer, I.; Dickinson, M. S.; Panzer, S.; Jaslan, D.; Navarro-Retamal, C.; Geiger, D.; Terpitz, U.; Becker, D.; Stroud, R. M.; Marten, I.; Hedrich, R.
10.1101/2021.12.22.473873 — plant biology — Posted on 2021-12-23
707 Metal transporter SLC39A14/ZIP14 modulates regulation between the gut microbiome and host metabolism
Thorn, T. L.; Mitchell, S. B.; Kim, Y.; Lee, M.-T.; Comrie, J. M. C.; Johnson, E. L.; Aydemir, T. B.
10.1101/2021.12.22.473859 — physiology — Posted on 2021-12-23
708 A discovery-based proteomics approach identifies protein disulfide isomerase (PDIA1) as a biomarker of β cell stress in type 1 diabetes
Syed, F.; Singhal, D.; Raedschelders, K.; Krishnan, P.; Bone, R. N.; McLaughlin, M. R.; Van Eyk, J. E.; Mirmira, R. G.; Yang, M.-L.; Mamula, M. J.; Wu, H.; Liu, X.; Evans-Molina, C.
10.1101/2021.12.22.473924 — physiology — Posted on 2021-12-23
712 Activation of retinoic acid receptor reduces metastatic prostate cancer bone lesions through blocking endothelial-to-osteoblast transition
Yu, G.; Corn, P. G.; Shen, P.; Song, J. H.; Lee, Y.-C.; Lin, S.-C.; Pan, J.; Agarwal, S. K.; Panaretakis, T.; Pacifici, M.; Logothetis, C. J.; Yu-Lee, L.-y.; Lin, S.-H.
10.1101/2021.12.22.473739 — cancer biology — Posted on 2021-12-23
713 Transcriptomic Profiling Reveals Cancer-Associated Fibroblasts as Potential Targets for the Prognosis and Treatment of Cervical Squamous Cell Carcinoma
Ou, Z.; Lin, S.; Qiu, J.; Ding, W.; Ren, P.; Chen, D.; Wang, J.; Tong, Y.; Wu, D.; Chen, A.; Deng, Y.; Cheng, M.; Peng, T.; Lu, H.; Yang, H.; Wang, J.; Jin, X.; Ma, D.; Xu, X.; Wang, Y.; Li, J.; Wu, P.
10.1101/2021.12.23.473944 — cancer biology — Posted on 2021-12-23
716 A rhythmically pulsing leaf-spring nanoengine that drives a passive follower
Centola, M.; Poppleton, E.; Centola, M.; Valero, J.; Sulc, P.; Famulok, M.
10.1101/2021.12.22.473833 — biophysics — Posted on 2021-12-23
718 Phenotyping Polarization Dynamics Of Immune Cells Using A Lipid Droplet - Cell Pairing Microfluidic Platform
Pinon, L.; Ruyssen, N.; Pineau, J.; Mesdjian, O.; Cuverlier, D.; Allena, R.; Asnacios, S.; Asnacios, A.; Pierobon, P.; Fattaccioli, J.
10.1101/2021.12.22.473360 — biophysics — Posted on 2021-12-23
719 The impact of low input DNA on the reliability of DNA methylation as measured by the Illumina Infinium MethylationEPIC BeadChip
Watkins, S. H.; Ho, K.; Testa, C.; Falk, L.; Soule, P.; Nguyen, L. V.; FitzGibbon, S.; Slack, C.; Chen, J. T.; Davey Smith, G.; De Vivo, I.; Simpkin, A. J.; Tilling, K.; Waterman, P. D.; Krieger, N.; Suderman, M.; Relton, C.
10.1101/2021.12.22.473840 — bioinformatics — Posted on 2021-12-23
722 Function-guided protein design by deep manifold sampling
Gligorijevic, V.; Berenberg, D.; Ra, S.; Watkins, A.; Kelow, S.; Cho, K.; Bonneau, R.
10.1101/2021.12.22.473759 — bioinformatics — Posted on 2021-12-23
725 Using Deep Learning for Gene Detection and Classification in Raw Nanopore Signals
Nykrynova, M.; Barton, V.; Jakubicek, R.; Bezdicek, M.; Lengerova, M.; Skutkova, H.
10.1101/2021.12.23.473143 — bioinformatics — Posted on 2021-12-23
726 Super-resolution vibrational imaging using expansion stimulated Raman scattering microscopy
Shi, L.; Klimas, A.; Gallagher, B.; Cheng, Z.; Fu, F.; Wijesekara, P.; Miao, Y.; Ren, X.; Zhao, Y.; Min, W.
10.1101/2021.12.22.473713 — bioengineering — Posted on 2021-12-23
728 Reconfigurable microfluidic circuits for isolating and retrieving cells of interest
Deroy, C.; Wheeler, J. H. R.; Rumianek, A. N.; Cook, P. R.; Durham, W. M.; Foster, K. R.; Walsh, E. J.
10.1101/2021.12.23.473995 — bioengineering — Posted on 2021-12-23
730 Characterization of antibiotic resistance in clinical isolates of Klebsiella pneumoniae in Denmark
Fang, X.; Westh, H.; Kemp, M.; Ellermann-Eriksen, S.; Palsson, B. O.; Johansen, H. K.; Monk, J. M.
10.1101/2021.12.20.473592 — genomics — Posted on 2021-12-23
732 Profiling subcellular localization of nuclear-encoded mitochondrial gene products in zebrafish
Uszczynska-Ratajczak, B.; Sugunan, S.; Kwiatkowska, M.; Migdal, M.; Carbonell-Sala, S.; Sokol, A. M.; Winata, C. L.; Chacinska, A.
10.1101/2021.12.22.473872 — genomics — Posted on 2021-12-23
735 ModelRevelator: Fast phylogenetic model estimation via deep learning
Burgstaller-Muehlbacher, S.; Crotty, S. M.; Schmidt, H. A.; Drucks, T.; von Haeseler, A.
10.1101/2021.12.22.473813 — evolutionary biology — Posted on 2021-12-23
741 Ureter single-cell and spatial mapping reveal cell types, architecture, and signaling networks
Ting, A. H.; Fink, E. E.; Sona, S.; Tran, U.; Desprez, P.-E.; Bradley, M.; Qiu, H.; Eltemamy, M.; Wee, A.; Wolkov, M.; Nicolas, M.; Min, B.; Haber, G.-P.; Wessely, O. H.; Lee, B. H.
10.1101/2021.12.22.473889 — developmental biology — Posted on 2021-12-23
742 The transcription factor Zic4 acts as a transdifferentiation switch
Vogg, M. C.; Ferenc, J.; Buzgariu, W. C.; Perruchoud, C.; Papasaikas, P.; Sanchez, P. G. L.; Nuninger, C.; Delucinge-Vivier, C.; Rampon, C.; Beccari, L.; Vriz, S.; Vincent, S.; Galliot, B.; Tsiairis, C.
10.1101/2021.12.22.473838 — developmental biology — Posted on 2021-12-23
743 Opto-Katanin: An Optogenetic Tool for Localized Microtubule Disassembly
Meiring, J. C. M.; Grigoriev, I.; Nijenhuis, W.; Kapitein, L. C.; Akhmanova, A.
10.1101/2021.12.22.473806 — cell biology — Posted on 2021-12-23
744 ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1
Bardwell, A. J.; Wu, B.; Sarin, K. Y.; Waterman, M. L.; Atwood, S. X.; Bardwell, L.
10.1101/2021.12.22.473898 — cell biology — Posted on 2021-12-23
745 NK cells acquire CCR5 and CXCR4 by trogocytosis in people living with HIV-1
Villalba, M.; Vo, D.-N.; Leventoux, N.; Campos-Mora, M.; Gimenez, S.; Corbeau, P.
10.1101/2021.12.21.473773 — immunology — Posted on 2021-12-23
746 ANTIBODY-INDEPENDENT ANTITUMOR EFFECTS OF CD32A-CHIMERIC RECEPTOR T CELLS: IMPLICATIONS FOR BREAST CANCER PROGNOSIS AND TREATMENT.
Sconocchia, G.; Lanzilli, G.; Cesarini, V.; Sivestris, D. A.; Arriga, R.; Rezvani, K.; Caratelli, S.; Chen, K.; Dou, J.; Cenciarelli, C.; Toietta, G.; Baldari, S.; Sconocchia, T.; De Paolis, F.; Aureli, A.; Iezzi, G.; Del Principe, M. I.; Venditti, A.; Ottaviani, A.; Spagnoli, G. C.
10.1101/2021.12.22.473841 — immunology — Posted on 2021-12-23
749 What do zebrafish prefer? Directional and color preferences in maze tasks
Marcon, M.; Benvenutti, R.; Gallas-Lopes, M.; Herrmann, A. P.; Piato, A.
10.1101/2021.12.22.473814 — neuroscience — Posted on 2021-12-23
751 Study of an FBXO7 patient mutation reveals Fbxo7 and PI31 co-regulate proteasomes and mitochondria
Al Rawi, S.; Simpson, L.; McDonald, N. Q.; Chernuha, V.; Elpeleg, O.; Zeviani, M. Q.; Barker, R. A.; Spiegel, R.; Laman, H.
10.1101/2021.12.22.473884 — neuroscience — Posted on 2021-12-23
753 Live-cell microscopy or fluorescence anisotropy with budded baculoviruses - which way to go with measuring ligand binding to M4 muscarinic receptors?
Tahk, M.-J.; Torp, J.; Ali, M. A. S.; Fishman, D.; Parts, L.; Grätz, L.; Müller, C.; Keller, M.; Veiksina, S.; Laasfeld, T.; Rinken, A.
10.1101/2021.12.22.473643 — pharmacology and toxicology — Posted on 2021-12-23
754 An enzyme-based system for the extraction of small extracellular vesicles from plants
Zhao, K.; sun, g.; zhao, q.; liu, g.; xie, m.; zou, y.; guo, z.; dong, j.; ye, j.; cao, y.; zheng, l.; liu, f.
10.1101/2021.12.22.473784 — pharmacology and toxicology — Posted on 2021-12-23
755 Comparative oncology reveals DNMT3B as a therapeutic vulnerability in soft-tissue sarcoma
Fuller, A. M.; DeVine, A.; Murazzi, I.; Mason, N. J.; Weber, K.; Eisinger, T. S. K.
10.1101/2021.12.22.473852 — cancer biology — Posted on 2021-12-23
757 The Biomechanics of the Locust Ovipositor Valves: a Unique Digging Apparatus
Das, R.; Gershon, S.; Bar-On, B.; Tadayon, M.; Ayali, A.; Pinchasik, B.-E.
10.1101/2021.12.22.473831 — bioengineering — Posted on 2021-12-23
759 Therapeutic advantages of combined gene/cell therapy strategies in a murine model of GM2 gangliosidosis
Sala, D.; Ornaghi, F.; Morena, F.; Argentati, C.; Valsecchi, M.; Alberizzi, V.; Di Guardo, R.; Bolino, A.; Aureli, M.; Martino, S.; Gritti, A.
10.1101/2021.12.22.473777 — genetics — Posted on 2021-12-23
762 The microRNA miR-132 is a key regulator of lymphatic vascular remodelling
Achen, M.; Arcucci, V.; Ishaq, M.; Roufail, S.; Dredge, K.; Bert, A.; Hackett-Jones, E.; Liu, R.; Pillman, K. A.; Fox, S.; Stacker, S. A.; Goodall, G.
10.1101/2021.12.22.473780 — cell biology — Posted on 2021-12-23
763 Novel regimens of bedaquiline-pyrazinamide combined with moxifloxacin, rifabutin, delamanid and/or OPC-167832 in murine tuberculosis models
Nuermberger, E.; Tasneen, R.; Garcia, A.; Converse, P. J.; Zimmerman, M. D.; Dartois, V. A.; Kurbatova, E. V.; Vernon, A.; Carr, W.; Stout, J. E.; Dooley, K. E.
10.1101/2021.12.21.473769 — microbiology — Posted on 2021-12-23
767 The role of the angular gyrus in semantic cognition - A synthesis of five functional neuroimaging studies
Kuhnke, P.; Chapman, C. A.; Cheung, V. K. M.; Turker, S.; Graessner, A.; Martin, S.; Williams, K. A.; Hartwigsen, G.
10.1101/2021.12.21.473704 — neuroscience — Posted on 2021-12-23
768 Directed motor actions and choice signalling drive cortical acetylcholine dynamics.
Zou, J.; Trinh, S.; Erskine, A.; Jing, M.; Yao, J.; Walker, S.; Li, Y.; Hires, S. A.
10.1101/2021.12.21.473699 — neuroscience — Posted on 2021-12-23
769 Revisiting PFA-mediated tissue fixation chemistry: FixEL enables trapping of small molecules in the brain to visualize their distribution dynamics
Nonaka, H.; Mino, T.; Sakamoto, S.; OH, J. H.; Watanabe, Y.; Ishikawa, M.; Tsushima, A.; Amaike, K.; Kiyonaka, S.; Tamura, T.; Aricescu, A. R.; Kakegawa, W.; Miura, E.; Yuzaki, M.; Hamachi, I.
10.1101/2021.12.21.473647 — neuroscience — Posted on 2021-12-23
772 The African mosquito-borne diseasosome: Geographical patterns and range expansion
Lehmann, T.; Kouam, C.; Woo, J.; Diallo, M.; Wilkerson, R.; Linton, Y.-M.
10.1101/2021.12.21.473756 — zoology — Posted on 2021-12-23
773 CRISPR/Cas9 knockout of EPFL10 reduces stomatal density while maintaining photosynthesis and enhancing water conservation in rice
Karavolias, N.; Patel, D.; Seong, K.; Tjahjadi, M.; Gueorguieva, G.-A.; Tanaka, J.; Dahlbeck, D.; Cho, M.-J.; Niyogi, K. K.; Staskawicz, B. J.
10.1101/2021.12.21.473329 — plant biology — Posted on 2021-12-23
774 The class I TCP transcription factor AtTCP8 is a modulator of phytohormone-responsive signaling networks
Spears, B. J.; McInturf, S. A.; Chlebowski, M.; Su, J.; Mendoza-Cozatl, D. G.; Gassmann, W.
10.1101/2021.12.21.473710 — plant biology — Posted on 2021-12-23
775 The C-terminal tail of polycystin-1 suppresses cystic disease in a mitochondrial enzyme-dependent fashion
Onuchic, L.; Padovano, V.; Schena, G.; Rajendran, V.; Dong, K.; Gresko, N. P.; Shi, X.; Shen, H.; Somlo, S.; Caplan, M. J.
10.1101/2021.12.21.473680 — physiology — Posted on 2021-12-23
789 Hemicentin mediated type IV collagen assembly strengthens juxtaposed basement membrane linkage
Gianakas, C. A.; Keeley, D. P.; Ramos-Lewis, W.; Park, K.; Jayadev, R.; Chi, Q.; Sherwood, D. R.
10.1101/2021.12.21.473673 — developmental biology — Posted on 2021-12-23
791 Myofibroblast Senescence Promotes Arrhythmogenic Remodeling in the Aged Infarcted Rabbit Heart
Baggett, B.; Murphy, K.; Sengun, E.; Mi, E.; Cao, Y.; Turan, N.; Lu, Y.; Schofield, L.; Kim, T. Y.; Kabakov, A.; Bronk, P.; Qu, Z.; Camelliti, P.; Dubielecka, P.; Terentyev, D.; Del Monte, F.; Choi, B.-R.; Sedivy, J.; Koren, G.
10.1101/2021.12.21.473692 — cell biology — Posted on 2021-12-23
792 A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction
Bender, R. H. F.; O'Donnell, B. T.; Shergill, B.; Pham, B. Q.; Juat, D. J.; Hatch, M. S.; Shirure, V. S.; Wortham, M.; Nguyen-Ngoc, K.-V.; Jun, Y.; Gaetani, R.; Christman, K. L.; Teyton, L.; George, S. C.; Sander, M.; Hughes, C. C.
10.1101/2021.12.21.473744 — cell biology — Posted on 2021-12-23
795 Induction of flight via midbrain projections to thecuneiform nucleus
Tsang, E. F.; Orlandini, C.; Sureka, R.; Crevenna, A. H.; Perlas, E.; Prankerd, I.; Masferrer, M. E.; Gross, C. T.
10.1101/2021.12.21.473683 — neuroscience — Posted on 2021-12-23
799 CNTF enhances aerobic glycolysis and anabolic activities in degenerating retinas
Rhee, K. D.; Wang, Y.; Hoeve, J. t.; Stiles, L.; Nguyen, T. T. T.; Zhang, X.; Vergnes, L.; Reue, K.; Shirihai, O. S.; Bok, D.; Yang, X.-J.
10.1101/2021.12.21.473752 — neuroscience — Posted on 2021-12-23
802 Harmonizing labeling and analytical strategies to obtain protein turnover rates in intact adult animals.
Hammond, D. E.; Simpson, D. M.; Franco, C.; Muelas, M. W.; Waters, J.; Ludwig, R. W.; Prescott, M. C.; Hurst, J. L.; Beynon, R. J.; Lau, E.
10.1101/2021.12.13.472439 — physiology — Posted on 2021-12-23
803 Depriving mice of sleep also deprives of food
Đukanovic, N.; La Spada, F.; Emmenegger, Y.; Niederhäuser, G.; Preitner, F.; Franken, P.
10.1101/2021.12.21.473656 — physiology — Posted on 2021-12-23
804 Evaluation of Commercially Available Glucagon Receptor Antibodies and Glucagon Receptor Expression
Billeschou Bomholt, A.; Dall Johansen, C.; Kjeldsen, S. A. S.; Douglas Galsgaard, K.; Bager Christensen, J.; Winther-Soerensen, M.; Serizawa, R.; Hornum, M.; Porrini, E.; Pedersen, J.; Oerskov, C.; Gluud, L. L.; Mehlin Soerensen, C.; Holst, J. J.; Albrechtsen, R.; Wewer Albrechtsen, N. J.
10.1101/2021.12.21.473442 — physiology — Posted on 2021-12-23
807 DNA fluctuations reveal the size and dynamics of topological domains
Vanderlinden, W.; Skoruppa, E.; Kolbeck, P. J.; Carlon, E.; Lipfert, J.
10.1101/2021.12.21.473646 — biophysics — Posted on 2021-12-23
811 L-type calcium channel blocker increases VEGF concentrations in retinal cells and human serum
Kumar, A.; Mutter, S.; Parente, E.; Harjutsalo, V.; Lithovius, R.; Mathavan, S.; Forsblom, C.; Lehto, M.; Hiltunen, T. P.; Kontula, K.; Groop, P.-H.
10.1101/2021.12.21.473644 — pharmacology and toxicology — Posted on 2021-12-23
812 On the reproductive mechanism of Gram-negative protocells
Kanaparthi, D.; Lampe, M.; Zhu, B.; Klingl, A.; Lueders, T.; Schwille, P.
10.1101/2021.11.25.470037 — biophysics — Posted on 2021-12-23
814 Multi-layered networks of SalmoNet2 enable strain comparisons of the Salmonella genus on a molecular level
Olbei, M. L.; Bohar, B.; Fazekas, D.; Madgwick, M.; Sudhakar, P.; Hautefort, I.; Metris, A.; Baranyi, J.; Kingsley, R. A.; Korcsmaros, T.
10.1101/2021.12.20.473597 — systems biology — Posted on 2021-12-23
815 Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects
Gopalswamy, M.; Kroeger, T.; Bickel, D.; Frieg, B.; Akter, S.; Schott-Verdugo, S.; Viegas, A.; Pauly, T.; Mayer, M.; Przibilla, J.; Reiners, J.; Nagel-Steger, L.; Smits, S. H. J.; Groth, G.; Etzkorn, M.; Gohlke, H.
10.1101/2021.12.22.473911 — biophysics — Posted on 2021-12-23
817 Glycolytic flux-signaling controls mouse embryo mesoderm development
Miyazawa, H.; Snaebjornsson, M. T.; Prior, N.; Kafkia, E.; Hammaren, H. M.; Tsuchida-Straeten, N.; Patil, K. R.; Beck, M.; Aulehla, A.
10.1101/2021.12.20.473441 — developmental biology — Posted on 2021-12-23
818 THEMIS is a priming substrate of non-receptor tyrosine phosphatase PTPN6/SHP1 and plays dual roles during T cell development
Zhang, J.; Zuo, E.; Song, M.; Chen, L.; Jiang, Z.; Chen, S.; Xiong, X.; Wang, Y.; Hao, P.; Horng, T.; Zhuang, M.; Zhang, L.; Wang, H.; Fan, G.
10.1101/2021.12.21.473566 — cell biology — Posted on 2021-12-23
823 Inferring cell-cell interactions from pseudotime ordering of scRNA-Seq data
Li, D.; Velazquez, J. J.; Ding, J.; Hislop, J.; Ebrahimkhani, M. R.; Bar-Joseph, Z.
10.1101/2021.07.28.454054 — bioinformatics — Posted on 2021-12-22
824 Bulk segregant analysis reveals environment x genotype interactions determining malaria parasite growth
Kumar, S.; Li, X.; McDew-White, M.; Reyes, A.; Delgado, E.; Sayeed, A.; Haile, M.; Abatiyow, B. A.; Kennedy, S.; Carmago, N.; Checkley, L.; Brenneman, K. V.; Button-Simons, K.; Duraisingh, M. T.; Cheeseman, I.; Kappe, S.; Nosten, F.; Ferdig, M.; Vaughan, A.; Anderson, T.
10.1101/2020.09.12.294736 — genetics — Posted on 2021-12-22
834 BFG-PCA: tools and resources that expand the potential for binary protein interaction discovery
Evans-Yamamoto, D.; Rouleau, F. D.; Nanda, P.; Makanae, K.; Liu, Y.; Despres, P. C.; Matsuo, H.; Seki, M.; Dube, A. K.; Ascencio, D.; Yachie, N.; Landry, C. R.
10.1101/2021.07.27.453987 — systems biology — Posted on 2021-12-22
839 A lung targeted miR-29 Mimic as a Therapy for Pulmonary Fibrosis
Chioccioli, M.; Subhadeep, R.; Rigby, K.; Newell, R.; Dansereau, O.; Pestano, L.; Dickinson, B.; Ahangari, F.; Jankins, G.; Iain, S.; Saini, G.; Johnson, S. R.; Braybrooke, R.; Herazo-Maya, J.; Aurelien, N.; Yu, G.; Sauler, M.; DeIuliis, G.; Montgomery, R. L.; Kaminski, N.
10.1101/2021.12.22.473724 — molecular biology — Posted on 2021-12-22
842 Using antibody synergy to engineer a high potency biologic cocktail against C. difficile
Zhao, H.; Tasch, M.; Dodds, M.; Gewe, M.; Martinez, A.; Hutton, M.; Keeney, K.; Pollock, A.; Jester, B.; Khuong, N.; Zhang, M.; Brady, C.; Heinnickel, M.; Tabakh, H.; Sanjaya, N.; Cruickshank, K.; Paddock, T.; Ertel, S.; Struyvenberg, S.; Dang, J.; Shanitta, C.; Fletcher, D.; Goetsch, L.; Gamble, C.; Mileto, S.; Heselpoth, R.; Lyras, D.; Behnke, C.; Fischetti, V.; Finrow, B.; Roberts, J. M.
10.1101/2021.12.21.473715 — bioengineering — Posted on 2021-12-22
843 Structure of anchorless RML prion reveals motif variation between strains
Hoyt, F.; Standke, H. G.; Artikis, E.; Schwartz, C. L.; Hansen, B.; Li, K.; Hughson, A. G.; Manca, M.; Thomas, O. R.; Raymond, G. J.; Baron, G. S.; Caughey, B.; Kraus, A.
10.1101/2021.12.22.473909 — biochemistry — Posted on 2021-12-22
852 Biofilm matrix proteome of clinical strain of P. aeruginosa
Egorova, D. A.; Solovyev, A. A.; Polyakov, N. B.; Danilova, K. A.; Scherbakova, A. A.; Kravtsov, I. N.; Dmitrieva, M. A.; Tutykhina, I. L.; Egorova, Y. M.; Gintsburg, A. L.
10.1101/2021.12.21.473640 — microbiology — Posted on 2021-12-22
855 SerpinB3 drives cancer stem cell survival in glioblastoma
Lauko, A.; Volovetz, J.; Turaga, S. M.; Bayik, D.; Watson, D. C.; Silver, D. J.; Mitchell, K.; Mulkearns-Hubert, E.; Desai, K.; Midha, M.; Hao, J.; McCortney, K.; Steffens, A.; Naik, U.; Ahluwalia, M. S.; Bao, S.; Horbinski, C.; Yu, J.; Lathia, J. D.
10.1101/2021.12.21.473663 — cancer biology — Posted on 2021-12-22
857 A DNA-based optical force sensor for live-cell applications
Jayachandran, C.; Ghosh, A.; Prabhune, M.; Bath, J.; Turberfield, A. J.; Hauke, L.; Enderlein, J.; Rehfeldt, F.; Schmidt, C. F.
10.1101/2021.12.21.473677 — biophysics — Posted on 2021-12-22
858 ATP:Mg2+ shapes condensate properties of rRNA-NPM1 in vitro nucleolus model and its partitioning of ribosomes
Yewdall, N. A.; Andre, A. A. M.; van Haren, M. H. I.; Nelissen, F. H. T.; Jonker, A.; Spruijt, E.
10.1101/2021.12.22.473778 — biophysics — Posted on 2021-12-22
862 The human RNA polymerase I structure reveals an HMG-like transcription factor docking domain specific to metazoans
Daiss, J. L.; Pilsl, M.; Straub, K.; Bleckmann, A.; Höcherl, M.; Heiss, F. B.; Abascal-Palacios, G.; Ramsay, E.; Tluckova, K.; Mars, J.-C.; Bruckmann, A.; Bernecky, C.; Lamour, V.; Panov, K.; Vannini, A.; Moss, T.; Engel, C.
10.1101/2021.12.22.473891 — biochemistry — Posted on 2021-12-22
864 Conjunctival epithelial cells resist productive SARS-CoV-2 infection
Lako, M.; Jackson, R. M.; Hatton, C. F.; Spegarova, J. S.; Georgiou, M.; Collin, J.; Stephenson, E.; Vernon, B.; Haq, I. J.; Hussain, R.; Coxhead, J. M.; Mudhar, H. S.; Wagner, B.; Hasoon, M.; Davie, T.; Rooney, P.; Khan, C. M. A.; Ward, C.; Brodlie, M.; Haniffa, M.; Hambleton, S.; Armstrong, L.; Figueiredo, F.; Queen, R.; Duncan, C. J.
10.1101/2021.12.20.473523 — cell biology — Posted on 2021-12-22
865 Enhanced microvasculature formation and patterning in iPSC-derived kidney organoids cultured in physiological hypoxia
Schumacher, A.; Roumans, N.; Rademakers, T.; Joris, V.; Eischen-Loges, M. J.; van Griensven, M.; LaPointe, V.
10.1101/2021.12.22.473849 — cell biology — Posted on 2021-12-22
866 Neutralization against Omicron SARS-CoV-2 from previous non-Omicron infection
Zou, j.; Xia, H.; Xie, X.; Kurhade, C.; Machado, R. R.; Weaver, S. C.; Ren, P.; Shi, P.-Y.
10.1101/2021.12.20.473584 — microbiology — Posted on 2021-12-22
867 The 'squalene route' to carotenoid biosynthesis is widespread in Bacteria.
Santana-Molina, C.; Henriques, V.; Hornero-Mendez, D.; Devos, D. P.; Rivas-Marin, E.
10.1101/2021.12.22.473825 — microbiology — Posted on 2021-12-22
869 Genomic diversity and biosynthetic capabilities ofsponge-associated chlamydiae
Dharamshi, J. E.; Gaarslev, N.; Steffen, K.; Martin, T.; Sipkema, D.; Ettema, T. J. G.
10.1101/2021.12.21.473556 — microbiology — Posted on 2021-12-22
870 Evolution of Gram+ Streptococcus pyogenes has maximized efficiency of the Sortase A cleavage site
Readnour, B. M.; Ayinuola, Y. A.; Russo, B.; Liang, Z.; Fischetti, V. A.; Ploplis, V.; Lee, S. W.; Castellino, F. J.
10.1101/2021.12.21.473763 — microbiology — Posted on 2021-12-22
871 Virus-like particles (VLPs) are efficient tools for boosting mRNA-induced antibodies
Vogt, A.-C. S.; Jörg, L.; Martina, B.; Krenger, P. S.; Chang, X.; Zeltins, A.; Vogel, M.; Mohsen, M. O.; Bachmann, M. F.
10.1101/2021.12.20.473421 — immunology — Posted on 2021-12-22
872 Blockade of TMPRSS2-mediated priming of SARS-CoV-2 by the N-terminal peptide of lactoferrin
Ohradanova-Repic, A.; Gebetsberger, L.; Tajti, G.; Ondrovicova, G.; Prazenicova, R.; Skrabana, R.; Barath, P.; Stockinger, H.; Leksa, V.
10.1101/2021.12.20.473447 — immunology — Posted on 2021-12-22
873 Immune escape of SARS-CoV-2 Omicron variant from mRNA vaccination-elicited RBD-specific memory B cells.
Sokal, A.; Broketa, M.; Meola, A.; Barba-Spaeth, G.; Fernandez, I.; Fourati, S.; Azzaoui, I.; de La Selle, A.; Vandenberghe, A.; Roeser, A.; Bouvier-Alias, M.; Crickx, E.; Languille, L.; Michel, M.; Godeau, B.; Gallien, S.; Melica, G.; Nguyen, Y.; Zarrouk, V.; Canoui-Poitrine, F.; Noizat-Pirenne, F.; Megret, J.; Pawlotsky, J.-M.; Fillatreau, S.; Simon-Loriere, E.; Weill, J.-C.; Reynaud, C.-A.; Rey, F. A.; Bruhns, P.; Chappert, P.; Mahevas, M.
10.1101/2021.12.21.473528 — immunology — Posted on 2021-12-22
874 mRNA-1273 and BNT162b2 mRNA vaccines have reduced neutralizing activity against the SARS-CoV-2 Omicron variant
Edara, V.-V.; Manning, K. E.; Ellis, M.; Lai, L.; Moore, K. M.; Foster, S. L.; Floyd, K.; Davis-Gardner, M. E.; Mantus, G.; Nyhoff, L. E.; Bechnack, S.; Alaaeddine, G.; Naji, A.; Samaha, H.; Lee, M.; Bristow, L.; Hussaini, L.; Ciric, C. R.; Nguyen, P.-V.; Gagne, M.; Roberts-Torres, J.; Henry, A. R.; Godbole, S.; Grakoui, A.; Sexton, M.; Piantadosi, A.; Waggoner, J. J.; Douek, D. C.; Anderson, E. J.; Rouphael, N.; Wrammert, J.; Suthar, M. S.
10.1101/2021.12.20.473557 — immunology — Posted on 2021-12-22
875 Longitudinal characterisation of phagocytic and neutralisation functions of anti-Spike antibodies in plasma of patients after SARS-CoV-2 infection.
Adhikari, A.; Abayasingam, A.; Rodrigo, C.; Agapiou, D.; Pandzic, E.; Brasher, N. A.; Fernando, B. S. M.; Keoshkerian, E.; Li, H.; Kim, H. N.; Lord, M.; Popovic, G.; Rawlinson, W.; Mina, M.; Post, J. J.; Hudson, B.; Gilroy, N.; Bartlett, A. W.; Ahlenstiel, G.; Grubor-Bauk, B.; Dwyer, D.; Konecny, P.; Lloyd, A. R.; Martinello, M.; Bull, R. A.; Tedla, N.
10.1101/2021.12.21.473774 — immunology — Posted on 2021-12-22
877 Engineered High-Affinity ACE2 Peptide Mitigates ARDS and Death Induced by Multiple SARS-CoV-2 Variants
Zhang, L.; Dutta, S.; Xiong, S.; Chan, M.; Chan, K. K.; Fan, T. M.; Bailey, K. L.; Lindeblad, M.; Cooper, L. M.; Rong, L.; Gugliuzza, A. F.; Shukla, D.; Procko, E.; Rehman, J.; Malik, A. B.
10.1101/2021.12.21.473668 — pharmacology and toxicology — Posted on 2021-12-22
878 From mass spectral features to molecules in molecular networks: a novel workflow for untargeted metabolomics.
Olivier-Jimenez, D.; Bouchouireb, Z.; Ollivier, S.; Mocquard, J.; Allard, P.-M.; Bernadat, G.; Chollet-Krugler, M.; Rondeau, D.; Boustie, J.; van der Hooft, J. J. J.; Wolfender, J.-L.
10.1101/2021.12.21.473622 — bioinformatics — Posted on 2021-12-22
880 Expanded FLP toolbox for spatiotemporal protein degradation and transcriptomic profiling in C. elegans
Fragoso-Luna, A.; Ayuso, C.; Eibl, M.; Munoz-Jimenez, C.; Benes, V.; Cases, I.; Askjaer, P.
10.1101/2021.12.21.473632 — genetics — Posted on 2021-12-22
881 dynamAedes: a unified modelling framework for invasive Aedes mosquitoes
Da Re, D.; Van Bortel, W.; Reuss, F.; Muller, R.; Boyer, S.; Montarsi, F.; Ciocchetta, S.; Arnoldi, D.; Marini, G.; Rizzoli, A.; L' Ambert, G.; Lacour, G.; Koenraadt, C. J. M.; Vanwambeke, S. O.; Marcantonio, M.
10.1101/2021.12.21.473628 — ecology — Posted on 2021-12-22
882 SARS-CoV-2 Omicron spike mediated immune escape, infectivity and cell-cell fusion
Meng, B.; Ferreira, I.; Abdullahi, A.; Saito, A.; Kimura, I.; Yamasoba, D.; Kemp, S. A.; Goonawardane, N.; Papa, G.; Fatihi, S.; Rathore, S.; Ikeda, T.; Toyoda, M.; Tan, T. S.; Kuramochi, J.; Mitsunaga, S.; Ueno, T.; Charles, O.; Collier, D.; CITIID-NIHR BioResource COVID-19 Collaboration, ; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Ecuador-COVID19 Consortium, ; Bradley, J.; Choi, J.; Smith, K.; Madissoon, E.; Meyer, K.; Mlcochova, P.; Doffinger, R.; Teichmann, S. A.; James, L.; Hyeon Lee, J.; Thukral, L.; Sato, K.; Gupta, R. K.
10.1101/2021.12.17.473248 — microbiology — Posted on 2021-12-22
884 Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies
Cao, Y. R.; Wang, J.; Jian, F.; Xiao, T.; Song, W.; Yisimayi, A.; Huang, W.; Li, Q.; Wang, P.; An, R.; Wang, J.; Wang, Y.; Niu, X.; Yang, S.; Liang, H.; Sun, H.; Li, T.; Yu, Y.; Cui, Q.; Liu, S.; Yang, X.; Du, S.; Zhang, Z.; Hao, X.; Shao, F.; Jin, R.; Wang, X.; Xiao, J.; Wang, Y.; Xie, X. S.
10.1101/2021.12.07.470392 — immunology — Posted on 2021-12-22
886 Mouse frontal cortex mediates additive multisensory decisions
Coen, P.; Sit, T. P.; Wells, M. J.; Carandini, M.; Harris, K. D.
10.1101/2021.04.26.441250 — neuroscience — Posted on 2021-12-22
887 Isotropic Three-Dimensional Dual-Color Super-Resolution Microscopy with Metal-Induced Energy Transfer
Thiele, J. C.; Jungblut, M.; Helmerich, D. A.; Tsukanov, R.; Chizhik, A.; Chizhik, A. I.; Schnermann, M.; Sauer, M.; Nevskyi, O.; Enderlein, J.
10.1101/2021.12.20.473473 — biophysics — Posted on 2021-12-22
888 Tumour mutations in long noncoding RNAs that enhance cell fitness
Esposito, R.; Lanzos, A.; Polidori, T.; Guillen-Ramirez, H.; Merlin, B.; Mela, L.; Zoni, E.; Buechi, I.; Hovhannisyan, L.; McCluggage, F.; Medo, M.; Basile, G.; Meise, D. F.; Ramnarayanan, S.; Zwyssig, S.; Wenger, C.; Schwarz, K.; Vancura, A.; Bosch-Guiteras, N.; JuliKruithof-deo, M.; Zimmer, Y.; Medova, M.; Stroka, D.; Fox, A.; Johnson, R.
10.1101/2021.11.06.467555 — genomics — Posted on 2021-12-22
889 Genetic Analysis of Human RNA Binding Motif Protein 48 (RBM48) Reveals an Essential Role in U12-Type Intron Splicing
Siebert, A. E.; Corll, J.; Gronevelt, J. P.; Levine, L.; Hobbs, L. M.; Kenney, C.; Davenport, R.; Settles, A. M.; Barbazuk, W. B.; Westrick, R. J.; Madlambayan, G. J.; Lal, S.
10.1101/2020.07.18.209528 — genetics — Posted on 2021-12-22
893 Applying computer vision to digitised natural history collections for climate change research: temperature-size responses in British butterflies
Wilson, R. J.; de Siqueira, A. F.; Brooks, S. J.; Price, B. W.; Simon, L. M.; van der Walt, S. J.; Fenberg, P. B.
10.1101/2021.12.21.473511 — ecology — Posted on 2021-12-22
895 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses
Dejnirattisai, W.; Huo, J.; Zhou, D.; Zahradni_k, J.; Supasa, P.; Liu, C.; Duyvesteyn, H. M. E.; Ginn, H.; Mentzer, A. J.; Tuekprakhon, A.; Nutalai, R.; Wang, B. -; Dijokaite, A.; Khan, S.; Avinoam, O.; Bahar, M.; Skelly, D.; Adele, S.; Johnson, S.; Amini, A.; Ritter, T.; Mason, C.; Dold, C.; Pan, D.; Assadi, S.; Bellass, A.; Omo-Dare, N.; Koeckerling, D.; Flaxman, A.; Jenkin, D.; Aley, P. K.; Voysey, M.; Clemens, S. A. C.; Naveca, F. G.; Nascimento, V.; Nascimento, F.; da Costa, C. F.; Resende, P. C.; Pauvolid-Correa, A.; Siqueira, M. M.; Baillie, V.; Serafin, N.; Ditse, Z.; Silva, K. D.; Mad
10.1101/2021.12.03.471045 — microbiology — Posted on 2021-12-22
897 Leukocyte cytokine responses in adult patients with mitochondrial DNA defects
Karan, K. R.; Trumpff, C.; Cross, M.; Englestad, K. M.; Marsland, A. L.; McGuire, P.; Hirano, M.; Picard, M.
10.1101/2021.12.13.472449 — immunology — Posted on 2021-12-22
899 HSP70-binding motifs function as protein quality control degrons
Abildgaard, A. B.; Petersen, S. D.; Larsen, F. B.; Kampmeyer, C.; Johansson, K. E.; Stein, A.; Ravid, T.; Andreasson, C.; Jensen, M. K.; Lindorff-Larsen, K.; Hartmann-Petersen, R.
10.1101/2021.12.22.473789 — biochemistry — Posted on 2021-12-22
902 5-aminolevulinic acid-photodynamic therapy ameliorates cutaneous granuloma by killing drug-resistant Mycobacterium marinum
Yang, Z.; Feng, Y.; Pang, Z.; Li, D.; Wang, S.; Chen, H.; Jiang, M.; Yan, H.; Li, T.; Fu, H.; Xiong, H.; Shi, D.
10.1101/2021.12.20.473605 — microbiology — Posted on 2021-12-22
906 An ancestral interaction module promotes oligomerisation in divergent mitochondrial ATP synthases
Gahura, O.; Muhleip, A.; Hierro-Yap, C.; Panicucci, B.; Jain, M.; Slapnickova, M.; Zikova, A.; Amunts, A.
10.1101/2021.10.10.463820 — molecular biology — Posted on 2021-12-22
908 GZMKhigh CD8+ T effector memory cells are associated with CD15high neutrophil abundance in early-stage colorectal tumors and predict poor clinical outcome.
Tiberti, S.; Catozzi, C.; Scirgolea, C.; Croci, O.; Ballerini, M.; Cagnina, D.; Soriani, C.; Macandog, A. D.; Nava Lauson, C. B.; Bertalot, G.; Petz, W. L.; Ravenda, S. P.; Licursi, V.; Paci, P.; Rasponi, M.; Fazio, N.; Ren, G.; Fumagalli-Romario, U.; Schaefer, M. H.; Campaner, S.; Lugli, E.; Nezi, L.; MANZO, T. o.
10.1101/2021.12.14.472046 — immunology — Posted on 2021-12-22
909 Antimicrobial resistance determinants in silage
Nagy, S. A.; Toth, A. G.; Papp, M.; Kaplan, S.; Solymosi, N.
10.1101/2021.12.12.472282 — genomics — Posted on 2021-12-22
911 'rbioacc': an R-package to analyse toxicokinetic data
Ratier, A.; Baudrot, V.; Kaag, M.; Siberchicot, A.; Lopes, C.; CHARLES, S.
10.1101/2021.09.08.459421 — ecology — Posted on 2021-12-22
912 Plasma membrane damage limits replicative lifespan in yeast and induces premature senescence in human fibroblasts
Kono, K.; Johmura, Y.; Moriyama, Y.; Suda, K.; Masukagami, Y.; Razali, N. B.; Chiu, Y.; Nishimura, K.; Barbee, H.; Takase, H.; Sugiyama, S.; Sato, Y.; Higashiyama, T.; Nakanishi, M.
10.1101/2021.03.26.437120 — cell biology — Posted on 2021-12-22
913 Esrrb is a cell cycle dependent priming factor balancing between pluripotency and differentiation
Herchcovici Levi, S.; Feldman, S.; Arnon, L.; Alajem, A.; Lahav, S.; Bavli, D.; Sun, X.; Buganim, Y.; Ram, O.; Awawdy, M.
10.1101/2020.08.03.234112 — molecular biology — Posted on 2021-12-22
919 Light-induced Patterning of Electroactive Bacterial Biofilms
Zhao, F.; Chavez, M. S.; Naughton, K. L.; Cole, C. M.; Gralnick, J. A.; El-Naggar, M. Y.; Boedicker, J. Q.
10.1101/2021.12.20.473588 — biophysics — Posted on 2021-12-21
920 Nfeature: A platform for computing features of nucleotide sequences
Mathur, M.; Patiyal, S.; Dhall, A.; Jain, S.; Tomer, R.; Arora, A.; Raghava, G. P. S.
10.1101/2021.12.14.472723 — bioinformatics — Posted on 2021-12-21
921 MOV10 facilitates messenger RNA decay in an N6-methyladenosine (m6A) dependent manner to maintain the mouse embryonic stem cells state
Mehravar, M.; Pandey, V. K.; Olshansky, M.; Dakle, P.; Bansal, D.; Dent, C.; Hathiwala, D.; Zhang, Z.; Gandhi, H.; Fulcher, A.; Huang, C.; Price, J.; Arumugam, S.; Ceman, S.; Balasubramanian, S.; Papas, B. N.; Morgan, M.; Miska, E. A.; Schittenhelm, R. B.; Tripathi, P.; Das, P. P.
10.1101/2021.08.11.456030 — biochemistry — Posted on 2021-12-21
922 Histone demethylome map reveals combinatorial gene regulatory functions in embryonic stem cells
Tripathi, P.; Dakle, P.; Mehravar, M.; Pandey, V. K.; Bullen, M. J.; Zhang, Z.; Hathiwala, D.; Kerenyi, M.; Woo, A.; Ghamari, A.; Cantor, A. B.; Wong, L. H.; Kim, J.; Glass, K.; Yuan, G.-C.; Pinello, L.; Orkin, S. H.; Das, P. P.
10.1101/2020.08.27.269514 — genomics — Posted on 2021-12-21
926 Ultra-deep through-skull mouse brain imaging via the combination of skull optical clearing and three-photon microscopy
He, M.; Li, D.; Zheng, Z.; Zhang, H.; Wu, T.; Geng, W.; Hu, Z.; Feng, Z.; Peng, S.; Zhu, L.; Xi, W.; Zhu, D.; Qian, J.
10.1101/2021.12.20.473469 — neuroscience — Posted on 2021-12-21
927 Striatal dopamine explains novelty-induced behavioral dynamics and individual variability in threat prediction
Akiti, K.; Tsutsui-Kimura, I.; Xie, Y.; Mathis, A.; Markowitz, J.; Anyoha, R.; Datta, S. R.; Mathis, M. W.; Uchida, N.; Watabe-Uchida, M.
10.1101/2021.12.21.473723 — neuroscience — Posted on 2021-12-21
928 Recurrence of cancer cell states across diverse tumors and their interactions with the microenvironment
Barkley, D.; Moncada, R.; Pour, M.; Liberman, D.; Dryg, I.; Werba, G.; Wang, W.; Baron, M.; Rao, A.; Xia, B.; Franca, G. S.; Weil, A.; Delair, D. F.; Hajdu, C.; Lund, A.; Osman, I.; Yanai, I.
10.1101/2021.12.20.473565 — cancer biology — Posted on 2021-12-21
929 Isotropic Three-Dimensional Dual-Color Super-Resolution Microscopy with Metal-Induced Energy Transfer
Thiele, J. C.; Jungblut, M.; Helmerich, D. A.; Tsukanov, R.; Chizhik, A.; Chizhik, A. I.; Schnermann, M.; Sauer, M.; Nevskyi, O.; Enderlein, J.
10.1101/2021.12.20.473473 — biophysics — Posted on 2021-12-21
938 Identification of novel genetic regions associated with resistance to European canker in apple
Karlström, A.; Gómez-Cortecero, A.; Nellist, C. F.; Ordidge, M.; Dunwell, J. M.; Harrison, R. J.
10.1101/2021.12.20.473552 — genetics — Posted on 2021-12-21
941 The origin and evolution of loqs2: a gene encoding an antiviral dsRNA binding protein in Aedes mosquitoes
Estevez-Castro, C. F.; Rodrigues, M. F.; Babarit, A.; Ferreira, F. V.; Marois, E.; Cogni, R.; Marques, J. T.; Olmo, R. P.
10.1101/2021.12.21.473503 — evolutionary biology — Posted on 2021-12-21
945 Stitchr: stitching coding TCR nucleotide sequences from V/J/CDR3 information
Heather, J. M.; Spindler, M. J.; Herrero Alonso, M.; Shui, Y. I.; Millar, D. G.; Johnson, D. S.; Cobbold, M.; Hata, A. N.
10.1101/2021.12.20.473544 — immunology — Posted on 2021-12-21
946 Transcriptomes and metabolism define mouse and human MAIT cell heterogeneity
Chandra, S.; Ascui, G.; Riffelmacher, T.; Chawla, A.; Ramirez-Suastegui, C.; Castelan, V. C.; Seumois, G.; Simon, H.; Murray, M. P.; Seo, G.-Y.; Premlal, A. L. R.; Verstichel, G.; Li, Y.; Lin, C.-H.; Greenbaum, J.; Lamberti, J.; Murthy, R.; Nigro, J.; Cheroutre, H.; Ottensmeier, C. H.; Hedrick, S. M.; Lu, L.-F.; Vijayanand, P.; Kronenberg, M.
10.1101/2021.12.20.473182 — immunology — Posted on 2021-12-21
947 IL-23 signaling prevents ferroptosis-driven renal immunopathology during candidiasis
Millet, N.; Solis, N. V.; Aquilar, D.; Lionakis, M. S.; Wheeler, R. T.; Jendzjowsky, N.; Swidergall, M.
10.1101/2021.12.19.473386 — immunology — Posted on 2021-12-21
948 Profiles and Dynamics of the Transcriptome of Microglial Cells Reveal their Inflammatory Status
Zohar, K.; Lezmi, E.; Reichert, F.; Eliyahu, T.; Rotshenker, S.; Weinstock, M.; Linial, M.
10.1101/2021.12.20.473548 — neuroscience — Posted on 2021-12-21
949 Unsupervised functional neurocartography of the Aplysia buccal ganglion
Costa, R. M.; Dharmaraj, V. A.; Homma, R.; Neveu, C. L.; Kristan, W. B.; Byrne, J. H.
10.1101/2021.12.20.473553 — neuroscience — Posted on 2021-12-21
950 Ultra-deep through-skull mouse brain imaging via the union of skull optical clearing and three-photon microscopy
He, M.; Li, D.; Zheng, Z.; Zhang, H.; Wu, T.; Geng, W.; Hu, Z.; Feng, Z.; Peng, S.; Zhu, L.; Xi, W.; Zhu, D.; Qian, J.
10.1101/2021.12.20.473469 — neuroscience — Posted on 2021-12-21
955 Membrane voltage fluctuations in human breast cancer cells
Quicke, P.; Sun, Y.; Arias-Garcia, M.; Acker, C. D.; Djamgoz, M. B. A.; Bakal, C.; Foust, A. J.
10.1101/2021.12.20.473148 — systems biology — Posted on 2021-12-21
958 ORA47 is a transcriptional regulator of a general stress response hub
Zeng, L.; Chen, H.; Wang, Y.; Hicks, D.; Ke, H.; Pruneda-Paz, J.; Dehesh, K.
10.1101/2021.12.20.473540 — plant biology — Posted on 2021-12-21
960 BACE1, but not BACE2, function is critical for metabolic disorders induced by high-fat diets in C57BL/6N mice
Rosahl, T. W.; Hyde, L. A.; Reilly, P. T.; Champy, M.-F.; Belongie, K. J.; Petit-Demouliere, B.; Sorg, T.; Jacobs, H.; Terry, R.; Scott, J. T.; Cuming, J. N.; Parker, E. M.; Kennedy, M. E.
10.1101/2021.12.20.473491 — physiology — Posted on 2021-12-21
962 Urine and Fecal Microbiota in a Canine Model of Bladder Cancer
Mrofchak, R.; Madden, C.; Evans, M. V.; Kisseberth, W. C.; Dhawan, D.; Knapp, D. W.; Hale, V. L.
10.1101/2021.12.20.472715 — cancer biology — Posted on 2021-12-21
963 BESFA: Bioinformatics based Evolutionary, Structural & Functional Analysis of Prostrate, Placenta, Ovary, Testis, and Embryo (POTE) Paralogs
Qazi, S.; Jit, B. P.; Das, A.; Karthikeyan, M.; Saxena, A.; Ray, M. D.; Singh, A. R.; Raza, K.; Jayaram, B.; Sharma, A.
10.1101/2021.12.20.473416 — cancer biology — Posted on 2021-12-21
964 Electrical activity between skin cells regulates melanoma initiation
Tagore, M.; Hergenreder, E.; Suresh, S.; Baron, M.; Perlee, S.; Melendez, S.; Hollmann, T. J.; Ideker, T.; Studer, L.; White, R.
10.1101/2021.12.19.473393 — cancer biology — Posted on 2021-12-21
965 Light-induced Patterning of Electroactive Bacterial Biofilms
Zhao, F.; Chavez, M. S.; Naughton, K. L.; Cole, C. M.; Gralnick, J. A.; El-Naggar, M. Y.; Boedicker, J. Q.
10.1101/2021.12.20.473588 — biophysics — Posted on 2021-12-21
969 Integrated view and comparative analysis of baseline protein expression in mouse and rat tissues
Wang, S.; Garcia-Seisdedos, D.; Prakash, A.; Kundu, D. J.; Collins, A.; George, N.; Fexova, S.; Moreno, P.; Papatheodorou, I.; Jones, A. R.; Vizcaino, J. A.
10.1101/2021.12.20.473413 — bioinformatics — Posted on 2021-12-21
971 Transmission dynamics and control of Sporotrichosis in domestic felines
Araujo, A. d. A.; Codeco, C.; F S Freitas, D.; M de Macedo, P.; A Pereira, S.; D F Gremiao, I.; Coelho, F.
10.1101/2021.12.20.473612 — bioinformatics — Posted on 2021-12-21
972 The BioImage Archive - home of life-sciences microscopy data
Hartley, M.; Kleywegt, G.; Patwardhan, A.; Sarkans, U.; Swedlow, J. R.; Brazma, A.
10.1101/2021.12.17.473169 — bioinformatics — Posted on 2021-12-21
979 Genomes of keystone Mortierella species lead to better in silico prediction of soil mycobiome functions from Taiwan's offshore islands
Lin, Y.-f.; Liu, W.-A.; Liu, Y.-C.; Lee, H.-H.; Lin, Y.-J.; Chang, E.-H.; Lu, M.-Y. J.; Chiu, C.-Y.; Tsai, I. J.
10.1101/2021.12.20.473467 — genomics — Posted on 2021-12-21
982 Leveraging TOPMed Imputation Server and Constructing a Cohort-Specific Imputation Reference Panel to Enhance Genotype Imputation among Cystic Fibrosis Patients
Sun, Q.; Liu, W.; Rosen, J. D.; Huang, L.; Pace, R. G.; Dang, H.; Gallins, P. J.; Blue, E. E.; Ling, H.; Corvol, H.; Strug, L.; Bamshad, M. J.; Gibson, R. L.; Pugh, E. W.; Blackman, S. M.; Cutting, G.; O'Neal, W. K.; Zhou, Y.-H.; Wright, F. A.; Knowles, M. R.; The Cystic Fibrosis Genome Project (CFGP) Consortium, ; Wen, J.; Li, Y.
10.1101/2021.12.20.473535 — genetics — Posted on 2021-12-21
983 Variant-to-gene-mapping followed by cross-species genetic screening identifies GPI-anchor biosynthesis as novel regulator of sleep
Palermo, J.; Chesi, A.; Zimmerman, A.; Sonti, S.; Lasconi, C.; Brown, E. B.; Pippin, J. A.; Wells, A. D.; Doldur-Balli, F.; Mazzotti, D.; Pack, A. I.; Gehrman, P. R.; Grant, S. F.; Keene, A. C.
10.1101/2021.12.19.472248 — genetics — Posted on 2021-12-21
984 Fine mapping of goat polledness variant in six Chinese native breeds
Li, Y.; chen, t.; Yang, M.; han, h.; Jiang, D.; wei, q.; Zhang, X.; Ao, Y.; Zhang, Q.-f.; Miao, Z.-p.; wang, r.; Li, Y.-l.; Chao, S.-y.; Li, L.; Zhang, T.-t.; Ming, F.
10.1101/2021.12.20.473573 — genetics — Posted on 2021-12-21
987 Transcriptome of the synganglion and characterization of the cys-loop ligand-gated ion channel gene family in the tick Ixodes ricinus.
Rispe, C.; Hervet, C.; de la Cotte, N.; Daveu, R.; Labadie, K.; Noel, B.; Aury, J.-M.; Thany, S.; Taillebois, E.; Cartereau, A.; Le Mauff, A.; Charvet, C. L.; Auger, C.; Neveu, C.; Plantard, O.
10.1101/2021.12.20.473502 — evolutionary biology — Posted on 2021-12-21
988 Global FAW population genomic signature supports complex introduction events across the Old World
Tay, W. T.; Rane, R.; Padovan, A.; Walsh, T.; Elfekih, S.; Downes, S.; Nam, K.; d'Alencon, E.; Zhang, J.; Wu, Y.; Negre, N.; Kunz, D.; Kriticos, D. J.; Czepak, C.; Otim, M. H.; Gordon, K. H.
10.1101/2020.06.12.147660 — evolutionary biology — Posted on 2021-12-21
989 Cellular development and evolution of the mammalian cerebellum
Sepp, M.; Leiss, K.; Sarropoulos, I.; Murat, F.; Okonechnikov, K.; Joshi, P.; Leushkin, E.; Mbengue, N.; Schneider, C.; Schmidt, J.; Trost, N.; Spaenig, L.; Giere, P.; Khaitovich, P.; Lisgo, S.; Palkovits, M.; Kutscher, L. M.; Anders, S.; Cardoso-Moreira, M.; Pfister, S. M.; Kaessmann, H.
10.1101/2021.12.20.473443 — evolutionary biology — Posted on 2021-12-21
991 Parental provisioning drives brain size in birds
Griesser, M.; Drobniak, S. M.; Graber, S. M.; van Schaik, C.
10.1101/2021.12.19.470191 — evolutionary biology — Posted on 2021-12-21
994 Long-lasting germinal center responses to a priming immunization with continuous proliferation and somatic mutation
Lee, J. H.; Sutton, H. J.; Cottrell, C. A.; Phung, I.; Ozorowski, G.; Sewall, L. M.; Nedellec, R.; Nakao, C.; Silva, M.; Richey, S. T.; Torres, J. L.; Lee, W.-H.; Georgeson, E.; Kubitz, M.; Hodges, S.; Mullen, T.-M.; Adachi, Y.; Cirelli, K. M.; Kaur, A.; Allers-Hernandez, C.; Fahlberg, M.; Grasperge, B. F.; Dufour, J. P.; Schiro, F.; Aye, P. P.; Carnathan, D. G.; Silvestri, G.; Shen, X.; Montefiori, D. C.; Veazey, R. S.; Ward, A. B.; Hangartner, L.; Burton, D. R.; Irvine, D. J.; Schief, W. R.; Crotty, S.
10.1101/2021.12.20.473537 — immunology — Posted on 2021-12-21
995 Myasthenia gravis-specific aberrant neuromuscular gene expression by medullary thymic epithelial cells in thymoma
Yasumizu, Y.; Ohkura, N.; Murata, H.; Kinoshita, M.; Funaki, S.; Nojima, S.; Kido, K.; Kohara, M.; Motooka, D.; Okuzaki, D.; Suganami, S.; Takeuchi, E.; Nakamura, Y.; Takeshima, Y.; Arai, M.; Tada, S.; Okumura, M.; Morii, E.; Shintani, Y.; Sakaguchi, S.; Okuno, T.; Mochizuki, H.
10.1101/2021.12.19.473411 — immunology — Posted on 2021-12-21
999 Single-Cell Atlas of Common Variable Immunodeficiency reveals germinal center-associated epigenetic dysregulation in B cell responses
Rodriguez-Ubreva, J.; Arutyunyan, A.; Bonder, M. J.; Del Pino-Molina, L.; Clark, S.; de la Calle-Fabregat, C.; Garcia-Alonso, L.; Handfield, L.-F.; Ciudad, L.; Andres-Leon, E.; Krueger, F.; Catala-Moll, F.; Rodriguez-Cortez, V. C.; Polanski, K.; Mamanova, L.; van Dongen, S.; Kiselev, V. Y.; Martinez-Saavedra, M. T.; Heyn, H.; Martin, J.; Warnatz, K.; Lopez-Granados, E.; Rodriguez-Gallego, C.; Stegle, O.; Kelsey, G. D.; Vento-Tormo, R.; Ballestar, E.
10.1101/2021.12.20.473453 — immunology — Posted on 2021-12-21
1001 Engraftment, fate, and function of HoxB8-conditional neutrophil progenitors in the unconditioned murine host
Cohen, J. T.; Danise, M.; Hinman, K. D.; Neumann, B. M.; Johnson, R.; Wilson, Z. S.; Chorzalska, A.; Dubielecka, P. M.; Lefort, C. T.
10.1101/2021.12.20.473543 — immunology — Posted on 2021-12-21
1002 GPR55 in B cells limits atherosclerosis development and regulates plasma cell maturation
Guillamat-Prats, R.; Hering, D.; Rami, M.; Haerdtner, C.; Sanovito, D.; Rinne, P.; Bindila, L.; Hristov, M.; Pagano, S.; Vuilleumier, N.; Schmid, S.; Janjic, A.; Enard, W.; Weber, C.; Maegdefessel, L.; Faussner, A.; Hilgendorf, I.; Steffens, S.
10.1101/2021.12.20.473518 — immunology — Posted on 2021-12-21
1003 Helminth infection modulates number and function of adipose tissue Tregs in high fat diet-induced obesity
Queiroz-Glauss, C.; Vieira, M.; Goncalves-Pereira, M. H.; Almeida, S.; Freire, R.; Gomes, M. A.; Alvarez-Leite, J.; Santiago, H. d. C.
10.1101/2021.12.20.473610 — immunology — Posted on 2021-12-21
1004 All-optical imaging and patterned stimulation with a one-photon endoscope
Zhang, J.; Hughes, R. N.; Kim, N.; Fallon, I. P.; bakhurin, K. I.; Kim, J.; Ulloa Severino, F. P.; Yin, H. H.
10.1101/2021.12.19.473349 — neuroscience — Posted on 2021-12-21
1007 Testing for implicit emotion regulation in childhood
Uh, S.; Siugzdaite, R.; Anywl-Irvine, A.; Dalmaijer, E. S.; Bignardi, G.; Smith, T. A.; Astle, D. E.
10.1101/2021.12.19.473228 — neuroscience — Posted on 2021-12-21
1008 In the back of your mind: Cortical mapping of tactile and proprioceptive paraspinal afferent inputs
Cole, D. M.; Stämpfli, P.; Gandia, R.; Schibli, L.; Gantner, S.; Schuetz, P.; Meier, M. L.
10.1101/2021.12.19.473341 — neuroscience — Posted on 2021-12-21
1011 Spatiotemporal dynamics of molecular expression pattern and intercellular interactions in glial scar responding to spinal cord injury
Gong, L.; Gu, Y.; Han, X.; Luan, C.; Wang, X.; Sun, Y.; Fang, M.; Yang, S.; Xu, L.; Sun, H.; Yu, B.; Gu, X.; zhou, s.
10.1101/2021.12.20.473346 — neuroscience — Posted on 2021-12-21
1012 Effectiveness and relationship between biased and unbiased measures of dopamine release and clearance
Everett, A. C.; Graul, B. E.; Watts, D. B.; Robinson, J. K.; Espana, R. A.; Siciliano, C. A.; Yorgason, J. T.
10.1101/2021.12.20.473490 — neuroscience — Posted on 2021-12-21
1013 Even well-practiced movements benefit from repetition
Sutter, K.; Oostwoud Wijdenes, L.; van Beers, R. J.; Medendorp, W. P.
10.1101/2021.12.21.473484 — neuroscience — Posted on 2021-12-21
1018 Integrated Proteomic and Metabolomic Analyses of the Mitochondrial Neurodegenerative Disease MELAS
Li, H.; Uittenbogaard, M.; Navarro, R.; Ahmed, M.; Gropman, A.; Chiaramello, A.; Hao, L.
10.1101/2021.12.18.473301 — systems biology — Posted on 2021-12-21
1019 MIAAIM: Multi-omics image integration and tissue state mapping using topological data analysis and cobordism learning
Hess, J. M.; Ilies, I.; Schapiro, D.; Iskra, J. J.; Abdelmoula, W. M.; Regan, M. S.; Theocharidis, G.; Wu, C. L.; Veves, A.; Agar, N. Y. R.; Sluder, A. E.; Poznansky, M. C.; Reeves, P. M.; Sirbulescu, R. F.
10.1101/2021.12.20.472858 — systems biology — Posted on 2021-12-21
1020 Oxytocin Signaling Regulates the Homeostatic Response to Cold Stress in Poikilothermic Vertebrates
Segev, A.; Krispin, S.; Olthof, A. M.; Hyatt, K.; Haller, L.; Barki, A.; Nitzan, T.; Levkowitz, G.; Kanadia, R. N.; Cnaani, A.; Biran, J.
10.1101/2021.12.20.472748 — physiology — Posted on 2021-12-21
1021 Endothelial Rbpj is essential for the education of tumour-associated macrophages
Mülfarth, R.; Alsina-Sanchis, E.; Moll, I.; Böhn, S.; Wiedmann, L.; Jordana Urriza, L.; Ziegelbauer, T.; Taylor, J.; De Angelis Rigotti, F.; Stögbauer, A.; Giaimo, B. D.; Cerwenka, A.; Borggrefe, T.; Fischer, A.; Rodriguez-Vita, J.
10.1101/2021.12.20.473423 — cancer biology — Posted on 2021-12-21
1023 Antibodies to ILT3 abrogate myeloid immunosuppression and enable tumor killing
Brandish, P. E.; Palmieri, A.; Ayanoglu, G.; Baker, J.; Bueno, R.; Byford, A.; Caniga, M.; Chappell, C.; Cherwinski, H.; Cua, D. J.; Du, X.; Fayadat-Dilman, L.; Hall, B. E.; Issafras, H.; Joyce-Shaikh, B.; Juan, V.; Levy, R. D.; Loboda, A.; Lunceford, J.; Mieczkowski, C.; Meehl, M.; Qu, Y.; Rosenzweig, M.; Singh, L.; Stivers, P.; Tramontozzi, P. J.; Vermilya, K.; Vroom, K.; Wilson, D. C.; Zhang, C.; Zhang-Hoover, J.
10.1101/2021.12.18.472552 — cancer biology — Posted on 2021-12-21
1024 Genetic and compound screens uncover factors modulating cancer cell response to indisulam
Pogacar, Z.; Groot, K.; Jochems, F.; Dos Santos Dias, M.; Morris, B.; Roosen, M.; Wardak, L.; De Conti, G.; Velds, A.; Lieftink, C.; Beijersbergen, R. L.; Bernards, R.; Leite de Oliveira, R.
10.1101/2021.12.20.473451 — cancer biology — Posted on 2021-12-21
1025 Intracranial Electric Field Recording During Multichannel Transcranial Electrical Stimulation
Wang, M.; Han, J.; Jiang, H.; Zhu, J.; Feng, W.; Chhatbar, P. Y.; Zhang, J.; Zhang, S.
10.1101/2021.12.19.473336 — biophysics — Posted on 2021-12-21
1033 Photothermal Dye-based Subcellular-sized Heat Spot Enabling the Modulation of Local Cellular Activities
Ferdinandus, F.; Suzuki, M.; Harada, Y.; Sarker, S. R.; Ishiwata, S. i.; Kitaguchi, T.; Arai, S.
10.1101/2021.12.19.471878 — bioengineering — Posted on 2021-12-21
1035 Delivery of CAR-T Cells in a Transient Injectable Stimulatory Hydrogel Niche Improves Treatment of Solid Tumors
Grosskopf, A. K.; Labanieh, L.; Klysz, D. D.; Roth, G.; Xu, P.; Adebowale, O.; Gale, E. C. G. C.; Jons, C. K.; Klich, J. H.; Yan, J.; Maikawa, C. L.; Correa, S.; Ou, B. S.; d'Aquino, A. I.; Cochran, J. R.; Chaudhuri, O.; Mackall, C. L.; Appel, E.
10.1101/2021.12.20.473538 — bioengineering — Posted on 2021-12-21
1036 De Novo Design of Immunoglobulin-like Domains
Chidyausiku, T. M.; Mendes, S. R.; Klima, J. C.; Eckhard, U.; Houliston, S.; Nadal, M.; Roel-Touris, J.; Guevara, T.; Haddox, H. K.; Moyer, A.; Arrowsmith, C. H.; Gomis-Rüth, F. X.; Baker, D.; Marcos, E.
10.1101/2021.12.20.472081 — biochemistry — Posted on 2021-12-21
1039 GRaNIE and GRaNPA: Inference and evaluation of enhancer-mediated gene regulatory networks applied to study macrophages
Kamal, A.; Arnold, C.; Claringbould, A.; Moussa, R.; Daga, N.; Nogina, D.; Kholmatov, M.; Servaas, N.; Mueller-Dott, S.; Reyes-Palomaresv, A.; Palla, G.; Sigalova, O.; Bunina, D.; Pabst, C.; Zaugg, J. B.
10.1101/2021.12.18.473290 — genomics — Posted on 2021-12-21
1045 Assessing the utility of marine filter feeders for environmental DNA (eDNA) biodiversity monitoring
Jeunen, G.-J.; Cane, J. S.; Ferreira, S.; Strano, F.; von Ammon, U.; Cross, H.; Day, R.; Hesseltine, S.; Ellis, K.; Urban, L.; Pearson, N.; Olmedo-Rojas, P.; Kardailsky, A.; Gemmell, N. J.; Lamare, M.
10.1101/2021.12.21.473722 — molecular biology — Posted on 2021-12-21
1046 An Atypical RNA Quadruplex Marks RNAs as Vectors for Gene Silencing
Roschdi, S.; Yan, J.; Nomura, Y.; Escobar, C. A.; Petersen, R. J.; Bingman, C. A.; Tonelli, M.; Montemayor, E. J.; Kennedy, S.; BUTCHER, S.
10.1101/2021.12.21.472683 — molecular biology — Posted on 2021-12-21
1048 Suicidal chemotaxis in bacteria
Oliveira, N. M.; Wheeler, J. H. R.; Deroy, C.; Booth, S. C.; Walsh, E. J.; Durham, W. M.; Foster, K. R.
10.1101/2021.12.21.473623 — microbiology — Posted on 2021-12-21
1049 MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells
Comar, C.; Otter, C.; Pfannenstiel, J.; Doerger, E.; Renner, D.; Tan, L. H.; Perlman, S.; Cohen, N.; Fehr, A.; Weiss, S. R.
10.1101/2021.12.20.473564 — microbiology — Posted on 2021-12-21
1050 Molecular epidemiology of Animal African Trypanosomosis in southwest Burkina Faso
Hounyeme, R. E.; Kabore, J.; Gimonneau, G.; Somda, M. B.; Salou, E.; Missihoum, A. A.; Bengaly, Z.; Jamonneau, V.; Boulange, A.
10.1101/2021.12.20.473611 — microbiology — Posted on 2021-12-21
1051 Overactive STAT3 drives accumulation of disease-associated CD21low B cells
Masle-Farquhar, E.; Peters, T. J.; Jackson, K. J.; Singh, M.; Ma, C. S.; Suan, D.; Uzel, G.; Chua, I.; Leiding, J. W.; Heiskanen, K.; Preece, K.; Kainulainen, L.; O Sullivan, M.; Cooper, M. A.; Seppänen, M. R.; Mustjoki, S.; Brothers, S.; Vogel, T.; Brink, R.; Tangye, S. G.; Reed, J. H.; Goodnow, C. C.
10.1101/2021.12.20.473595 — immunology — Posted on 2021-12-21
1053 Coupling of pupil- and neuronal population dynamics reveals diverse influences of arousal on cortical processing
Pfeffer, T.; Keitel, C.; Kluger, D. S.; Keitel, A.; Russmann, A.; Thut, G.; Donner, T. H.; Gross, J.
10.1101/2021.06.25.449734 — neuroscience — Posted on 2021-12-21
1056 Multi T1-weighted contrast imaging and T1 mapping with Compressed sensing FLAWS at 3T
Beaumont, J.; Fripp, J.; Raniga, P.; Acosta, O.; Ferre, J.-C.; McMahon, K.; Trinder, J.; Kober, T.; Gambarota, G.
10.1101/2021.12.18.473283 — neuroscience — Posted on 2021-12-21
1057 Notch inhibition promotes regeneration and immunosuppression supports cone survival in a zebrafish model of inherited retinal dystrophy
Fogerty, J.; Song, P.; Boyd, P.; Grabinski, S.; Hoang, T.; Reich, A.; Cianciolo, L.; Blackshaw, S.; Mumm, J. S.; Hyde, D.; Perkins, B.
10.1101/2021.12.19.473212 — neuroscience — Posted on 2021-12-21
1058 Functional Network Connectivity Imprint In Febrile Seizures
Acharya, U. V.; Panda, R.; Kulanthaivelu, K.; Saini, J.; Gupta, A. K.; Sankaran, B. P.; Raghavendra, K.; Mundlamuri, R. C.; Sinha, S.; Keshavamurthy, M.; Bharath, R. D.
10.1101/2021.12.18.473280 — neuroscience — Posted on 2021-12-21
1062 Dug: A Semantic Search Engine Leveraging Peer-Reviewed Knowledge to Span Biomedical Data Repositories
Waldrop, A. M.; Cheadle, J. B.; Bradford, K.; Preiss, A.; Chew, R.; Holt, J. R.; Braswell, N. T.; Watson, M.; Crerar, A.; Ball, C.; Kebede, Y.; Schreep, C.; Linebaugh, P. J.; Hiles, H.; Boyles, R.; Bizon, C.; Krishnamurthy, A.; Cox, S.
10.1101/2021.07.07.451461 — bioinformatics — Posted on 2021-12-21
1063 Popeye Domain-Containing Protein 1 Scaffolds a Complex of Adenylyl Cyclase 9 and the Two-Pore-Domain Potassium Channel TREK-1 in Heart
Baldwin, T. A.; Li, Y.; Marsden, A.; Schindler, R. F. R.; Zhang, M.; Carbajal, A. G.; Garcia, M. A.; Venna, V. R.; Brand, T.; Dessauer, C. W.
10.1101/2021.12.21.473719 — biochemistry — Posted on 2021-12-21
1066 Insight into the mechanism of H+-coupled nucleobase transport
Weng, J.; Zhou, X.; Wiriyasermkul, P.; Ren, Z.; Yan, X.; Chen, K.; Iturbe, E. G.; Zhou, M.; Quick, M.
10.1101/2021.12.20.473561 — biochemistry — Posted on 2021-12-21
1068 Structural and biophysical characterization of HNF-1A as a tool to study MODY3 diabetes variants
Kind, L.; Raasakka, A.; Molnes, J.; Aukrust, I.; Bjorkhaug, L.; Njolstad, P. R.; Kursula, P.; Arnesen, T.
10.1101/2021.12.20.473529 — biochemistry — Posted on 2021-12-21
1069 Fat Body Phospholipid State Dictates Hunger Driven Feeding Behavior
Kelly, K. P.; Alassaf, M.; Sullivan, C. E.; Brent, A. E.; Goldberg, Z. H.; Poling, M. E.; Dubrulle, J.; Rajan, A.
10.1101/2021.12.16.472854 — animal behavior and cognition — Posted on 2021-12-21
1070 The origins and functional effects of postzygotic mutations throughout the human lifespan
Rockweiler, N. B.; Ramu, A.; Nagirnaja, L.; Wong, W. H.; Noordam, M. J.; Drubin, C. W.; Huang, N.; Miller, B.; Todres, E. Z.; Vigh-Conrad, K. A.; Zito, A.; Small, K. S.; Ardlie, K. G.; Cohen, B. A.; Conrad, D. F.
10.1101/2021.12.20.473199 — genomics — Posted on 2021-12-21
1071 Deeply hidden genome organization directly mediated by SATB1
Kohwi, Y.; Grange, M.; Richards, H. W.; Liang, Y.-C.; Chuong, C.-M.; Kitagawa, Y.; Sakaguchi, S.; Botchkarev, V.; Taniguchi, I.; Kohwi-Shigematsu, T.
10.1101/2021.12.19.473323 — genomics — Posted on 2021-12-21
1072 Resistance to miltefosine results from amplification of the RTA3 floppase or inactivation of flippases in Candida parapsilosis
Bergin, S.; Zhao, F.; Ryan, A. P.; Müller, C. A.; Nieduszynski, C. A.; Zhai, B.; Rolling, T.; Hohl, T. M.; Morio, F.; Scully, J.; Wolfe, K. H.; Butler, G.
10.1101/2021.12.16.473093 — genomics — Posted on 2021-12-21
1075 No evidence for long-range male sex pheromones in two malaria mosquitoes
Poda, S. B.; Buatois, B.; Lapeyre, B.; Dormont, L.; Diabate, A.; Gnankine, O.; Dabire, R. K.; Roux, O.
10.1101/2020.07.05.187542 — ecology — Posted on 2021-12-21
1079 TSC22D4 interacts with Akt1 in response to metabolic and stress signals
Demir, S.; Wolff, G.; Wieder, A.; Maida, A.; Rahm, M.; Schnoelzer, M.; Hauck, S.; Szendroedi, J.; Herzig, S.; Uestuenel, B. E.
10.1101/2021.12.20.473554 — molecular biology — Posted on 2021-12-21
1082 Molecular features underlying Pseudomonas aeruginosa persistence in human plasma
Janet-Maitre, M.; Pont, S.; Masson, F.; Trouillon, J.; Robert-Genthon, M.; Dumestre-Perard, C.; Elsen, S.; Moriscot, C.; Bardoel, B.; Rooijakkers, S.; Cretin, F.; Attree, I.
10.1101/2021.12.21.473675 — microbiology — Posted on 2021-12-21
1083 Replication is the key barrier during the dual-host adaption of mosquito-borne flaviviruses
Zheng, A.; Wang, X.; Zhang, Y.; Liang, D.; Yuan, F.; Yan, Y.; Wang, Z.; Liu, P.; Qu, Q.; Zhang, X.
10.1101/2021.12.21.473591 — microbiology — Posted on 2021-12-21
1085 Human gut bifidobacteria inhibit the growth of the opportunistic fungal pathogen Candida albicans
Ricci, L.; Mackie, J.; Donachie, G. E.; Chapuis, A.; Mezerova, K.; Lenardon, M. D.; Brown, A. J.; Duncan, S. H.; Walker, A. W.
10.1101/2021.12.21.473717 — microbiology — Posted on 2021-12-21
1088 Pentosan polysulfate inhibits attachment and infection by SARS-CoV-2 in vitro: insights into structural requirements for binding.
Bertini, S.; Alekseeva, A.; Elli, S.; Pagani, I.; Zanzoni, S.; Eisele, G.; Krishnan, R.; Maag, K. P.; Reiter, C.; Lenhart, D.; Gruber, R.; Yates, E. A.; Vicenzi, E.; Naggi, A.; Bisio, A.; Guerrini, M.
10.1101/2021.12.19.473359 — biochemistry — Posted on 2021-12-21
1091 GLP is critical for oogenesis exhibiting a G9A-independent role in transcriptional repression
Demond, H.; Hanna, C. W.; Castillo-Fernandez, J.; Santos, F.; Papachristou, E. K.; Segonds-Pichon, A.; Kishore, K.; D'Santos, C. S.; Kelsey, G.
10.1101/2021.12.20.473460 — developmental biology — Posted on 2021-12-21
1093 Polarized α-synuclein trafficking and transcytosis across Brain Endothelial Cells via Rab7-decorated carriers
Alam, P.; Holst, M. R.; Laursen, L.; Nielsen, J.; Nielsen, S.; Brewer, J.; Jensen, P. H.; Otzen, D.; Nielsen, M. S.
10.1101/2021.12.21.473642 — cell biology — Posted on 2021-12-21
1094 OMA1 mediates local and global stress responses against protein misfolding in CHCHD10 mitochondrial myopathy
Shammas, M. K.; Huang, X.; Wu, B. P.; Song, I.; Randolph, N.; Li, Y.; Bleck, C. K. E.; Springer, D.; Fratter, C.; Barbosa, I.; Powers, A. F.; Quiros, P. M.; Lopez-Otin, C.; Poulton, J.; Narendra, D. P.
10.1101/2021.12.21.473493 — cell biology — Posted on 2021-12-21
1096 Temporal associations of B and T cell immunity with robust vaccine responsiveness in a 16-week interval BNT162b2 regimen
Nayrac, M.; Dube, M.; Sannier, G.; Nicolas, A.; Marchitto, L.; Tastet, O.; Tauzin, A.; Brassard, N.; Beaudoin-Bussieres, G.; Vezina, D.; Gong, S. Y.; Benlarbi, M.; Gasser, R.; Laumaea, A.; Bourassa, C.; Gendron-Lepage, G.; Medjahed, H.; Goyette, G.; Ortega-Delgado, G.-G.; Laporte, M.; Niessl, J.; Gokool, L.; Morrisseau, C.; Arlotto, P.; Richard, J.; Tremblay, C.; Martel-Laferriere, V.; Finzi, A.; Kaufmann, D. E.
10.1101/2021.12.18.473317 — immunology — Posted on 2021-12-21
1097 Neuronal circuits integrating visual motion information in Drosophila
Shinomiya, K.; Nern, A.; Meinertzhagen, I.; Plaza, S. M.; Reiser, M. B.
10.1101/2021.12.20.473513 — neuroscience — Posted on 2021-12-21
1098 Small molecule v-ATPase inhibitor Etidronate lowers levels of ALS protein ataxin-2
Kim, G.; Nakayama, L.; Blum, J. A.; Akiyama, T.; Boeynaems, S.; Chakraborty, M.; Couthouis, J.; Tassoni-Tsuchida, E.; Rodriguez, C. M.; Bassik, M. C.; Gitler, A. D.
10.1101/2021.12.20.473567 — neuroscience — Posted on 2021-12-21
1101 The N-Terminal Carbamate is Key to High Cellular and Antiviral Potency for Boceprevir-Based SARS-CoV-2 Main Protease Inhibitors
Alugubelli, Y. R.; Geng, Z. Z.; Yang, K.; Shaabani, N.; Khatua, K.; Ma, X. R.; Vatansever, E. C.; Cho, C.-C.; Ma, Y.; Blankenship, L.; Yu, G.; Sankaran, B.; Li, P.; Allen, R.; Ji, H.; Xu, S.; Liu, W. R.
10.1101/2021.12.18.473330 — biochemistry — Posted on 2021-12-21
1102 Human embryos arrest in a quiescent-like state characterized by metabolic and zygotic genome activation problems
Yang, Y.; Shi, L.; Fu, X.; Ma, G.; Zhongzhou, Y.; Li, Y.; Zhou, Y.; Yuan, L.; Xia, Y.; Zhong, X.; Yin, P.; Sun, L.; Zhang, W.; Babarinde, I. A.; Wang, Y.; Zhao, X.; Hutchins, A. P.; Tong, G.
10.1101/2021.12.19.473390 — developmental biology — Posted on 2021-12-21
1103 Platr4 is an ESC-specific lncRNA that exhibits its function downstream on meso/endoderm lineage commitment
Hazra, R.; Brine, L.; Garcia, L.; Benz, B.; Chirathivat, N.; Shen, M. M.; Wilkinson, J. E.; Lyons, S.; Spector, D. L.
10.1101/2021.12.20.473435 — developmental biology — Posted on 2021-12-21
1105 Striking Antibody Evasion Manifested by the Omicron Variant of SARS-CoV-2
Liu, L.; Iketani, S.; Guo, Y.; Chan, J. F.-W.; Wang, M.; Liu, L.; Luo, Y.; Chu, H.; Huang, Y.; Nair, M. S.; Yu, J.; Chik, K. K.-H.; Yuen, T. T.-T.; Yoon, C.; To, K. K.-W.; Chen, H.; Yin, M. T.; Sobieszczyk, M. E.; Huang, Y.; Wang, H. H.; Sheng, Z.; Yuen, K.-Y.; Ho, D. D.
10.1101/2021.12.14.472719 — microbiology — Posted on 2021-12-21
1106 Targeting RTN4/NoGo-Receptor reduces levels of ALS protein ataxin-2
Rodriguez, C. M.; Bechek, S. C.; Jones, G. L.; Nakayama, L.; Akiyama, T.; Kim, G.; Solow-Cordero, D. E.; Strittmatter, S. M.; Gitler, A. D.
10.1101/2021.12.20.473562 — neuroscience — Posted on 2021-12-21
1107 Examining Batch Effect in Histopathology as a Distributionally Robust Optimization Problem
Hari, S. N.; Nyman, J.; Mehta, N.; Dietlein, F.; Rosenthal, J.; Jiang, B.; Chowdhury, A.; Elmarakeby, H.; Sengupta, E.; Umeton, R.; Van Allen, E. M.
10.1101/2021.09.14.460365 — cancer biology — Posted on 2021-12-21
1108 OMAMO: orthology-based model organism selection
Nicheperovich, A.; Altenhoff, A. M.; Dessimoz, C.; Majidian, S.
10.1101/2021.11.04.467067 — bioinformatics — Posted on 2021-12-21
1109 Neuronal population dynamics during motor plan cancellation in non-human primates
Pani, P.; Giamundo, M.; Giarrocco, F.; Mione, V.; Brunamonti, E.; Mattia, M.; Ferraina, S.
10.1101/774307 — neuroscience — Posted on 2021-12-21
1110 The catscape: spatial manifestation of a pet cat population with outdoor access
Bischof, R.; Hansen, N. R.; Skarsgard Nyheim, O.; Kisen, A.; Prestmoen, L.; Haugaasen, T.
10.1101/2021.12.20.473457 — ecology — Posted on 2021-12-21
1118 Disentangling the genetic basis of rhizosphere microbiome assembly in tomato
Oyserman, B. O.; Sarango Flores, S.; Griffioen, T.; van der Wijk, E.; Pronk, L.; Lokhorst, W.; Nurfikari, A.; Stopnisek, N.; Kupczok, A.; Cordovez, V.; Carrion, V. J.; Ligterink, W.; Snoek, B. L.; Medema, M. H.; Raaijmakers, J. M.
10.1101/2021.12.20.473370 — microbiology — Posted on 2021-12-21
1120 EARBOX: An open tool for high-throughput measurements of the spatial organization of maize ears and inference of novel traits
Oury, V.; Leroux, T.; Turc, O.; Chapuis, R.; Palaffre, C.; Tardieu, F.; Alvarez Prado, S.; Welcker, C.; Lacube, S.
10.1101/2021.12.20.473433 — plant biology — Posted on 2021-12-21
1122 A lineage-specific Exo70 is required for receptor kinase-mediated immunity in barley
Holden, S.; Bergum, M.; Green, P.; Bettgenhaeuser, J.; Hernandez-Pinzon, I.; Thind, A.; Clare, S. J.; Russell, J. M.; Hubbard, A.; Taylor, J.; Smoker, M.; Gardiner, M.; Civolani, L.; Cosenza, F.; Rosignoli, S.; Strugala, R.; Molnar, I.; Simkova, H.; Dolezel, J.; Schaffrath, U.; Barrett, M.; Salvi, S.; Moscou, M. J.
10.1101/2021.12.19.473371 — plant biology — Posted on 2021-12-21
1123 IDENTIFYING PLANT GENES SHAPING MICROBIOTA COMPOSITION IN THE BARLEY RHIZOSPHERE
Escudero-Martinez, C.; Coulter, M.; Alegria Terrazas, R.; Foito, A.; Kapadia, R.; Pietrangelo, L.; Maver, M.; Sharma, R.; Aprile, A.; Morris, J.; Hedley, P. E.; Maurer, A.; Pillen, K.; Naclerio, G.; Mimmo, T.; Abbott, J.; Waugh, R.; Barton, G. J.; Bulgarelli, D.
10.1101/2021.12.20.472907 — plant biology — Posted on 2021-12-21
1125 A global survey of specialized metabolic diversity encoded in bacterial genomes
Gavriilidou, A.; Kautsar, S. A.; Zaburannyi, N.; Krug, D.; Mueller, R.; Medema, M. H.; Ziemert, N.
10.1101/2021.08.11.455920 — genomics — Posted on 2021-12-21
1128 No evidence for long-range male sex pheromones in two malaria mosquitoes
Poda, S. B.; Buatois, B.; Lapeyre, B.; Dormont, L.; Diabate, A.; Gnankine, O.; Dabire, R. K.; Roux, O.
10.1101/2020.07.05.187542 — ecology — Posted on 2021-12-21
1129 Engineering selectivity of Cutibacterium acnes phages by epigenetic imprinting
Knoedlseder, N.; Nevot, G.; Fabrega, M.; Mir-Pedrol, J.; Sanvicente, M.; Campana-Sanz, N.; Lood, R.; Güell, M.
10.1101/2021.12.19.473365 — microbiology — Posted on 2021-12-21
1132 Lower Aβ-PET signal in white matter lesions relates to higher extracellular free water in mixed small vessel disease and Alzheimer's pathology
Ottoy, J.; Ozzoude, M.; Zukotynski, K.; Kang, M. S.; Adamo, S.; Scott, C.; Ramirez, J.; Swardfager, W.; Lam, B.; Bhan, A.; Mojiri, P.; Kiss, A.; Strother, S.; Bocti, C.; Borrie, M.; Chertkow, H.; Frayne, R.; Hsiung, R.; Laforce, R. J.; Noseworthy, M. D.; Prato, F. S.; Sahlas, D. J.; Smith, E. E.; Kuo, P. H.; Chad, J. A.; Pasternak, O.; Sossi, V.; Thiel, A.; Soucy, J.-P.; Tardif, J.-C.; Black, S. E.; Goubran, M.
10.1101/2021.12.17.473211 — neuroscience — Posted on 2021-12-21
1135 CRISPR-mediated Multiplexed Live Cell Imaging of Nonrepetitive Genomic Loci
Clow, P. A.; Du, M.; Jillette, N.; Taghbalout, A.; Zhu, J. J.; Cheng, A. W.
10.1101/2020.03.03.974923 — genomics — Posted on 2021-12-21
1142 Inter- and intra-tumor heterogeneity in EMT states confers functional diversity in cells that lead collective invasion.
Nasir, A.; Camacho, S.; McIntosh, A. T.; Graham, G. T.; Rahhal, R.; Huysman, M. E.; Riegel, A. T.; Pearson, G. W.
10.1101/2020.11.14.383232 — cancer biology — Posted on 2021-12-21
1143 HMMploidy: inference of ploidy levels from short-read sequencing data
Soraggi, S.; Rhodes, J.; Altinkaya, I.; Tarrant, O.; Balloux, F.; Fisher, M. C.; Fumagalli, M.
10.1101/2021.06.29.450340 — bioinformatics — Posted on 2021-12-21
1144 A single-cell atlas of breast cancer cell lines to study tumour heterogeneity and drug response
Gambardella, G.; Viscido, G.; Tumaini, B.; Isacchi, A.; Bosotti, R.; di Bernardo, D.
10.1101/2021.03.02.433590 — bioinformatics — Posted on 2021-12-21
1145 Making Common Fund data more Findable: Catalyzing a Data Ecosystem
Charbonneau, A. L.; Brady, A.; Canchi, S.; Carter, R.; Chard, K.; Clarke, D. J. B.; Creasy, H. H.; D'Arcy, M.; Giglio, M.; Gingrich, A.; Harris, R. M.; Hodges, T. K.; Jeon, M.; Kropiwnicki, E.; Lim, M. C. W.; Liming, R. L.; Mandal, M.; Munro, J. B.; Nadendla, S.; Romano, C.; Rocca-Serra, P.; Schuler, R. E.; Waldrop, A.; Williams, C.; Word, K.; Sansone, S.-A.; Ma'ayan, A.; Wagner, R.; Foster, I.; Kesselman, C.; Brown, C. T.; White, O.
10.1101/2021.11.05.467504 — bioinformatics — Posted on 2021-12-21
1149 Closed-loop optimization of transcranial magnetic stimulation with electroencephalography feedback
Tervo, A. E.; Nieminen, J. O.; Lioumis, P.; Metsomaa, J.; Souza, V. H.; Sinisalo, H.; Stenroos, M.; Sarvas, J.; Ilmoniemi, R. J.
10.1101/2021.08.31.458148 — bioengineering — Posted on 2021-12-21
1151 Serum glycoprotein markers in non-alcoholic steatohepatitis and hepatocellular carcinoma
Ramachandran, P.; Xu, G.; Huang, H. H.-L.; Rice, R.; Zhou, B.; Lindpaintner, K.; Serie, D.
10.1101/2021.09.30.462486 — biochemistry — Posted on 2021-12-21
1152 Somewhere I belong: phylogeny and morphological evolution in a species-rich lineage of ectoparasitic flatworms infecting cichlid fishes
Cruz-Laufer, A. J.; Pariselle, A.; Jorissen, M. W. P.; Muterezi Bukinga, F.; Al Assadi, A.; Van Steenberge, M.; Koblmueller, S.; Sturmbauer, C.; Smeets, K.; Artois, T.; Vanhove, M. P. M.
10.1101/2021.03.22.435939 — evolutionary biology — Posted on 2021-12-21
1156 TCAB1 prevents nucleolar accumulation of the telomerase RNA to promote telomerase assembly
Al-Masraf, B. S.; Perez, G. I.; Adams-Boone, K.; Cohen, S. B.; Han, L.; Yu, K.; Schmidt, J. C.
10.1101/2021.05.27.445986 — cell biology — Posted on 2021-12-21
1159 SARS-CoV-2 spike conformation determines plasma neutralizing activity
Bowen, J. E.; Walls, A. C.; Joshi, A.; Sprouse, K. R.; Stewart, C.; Tortorici, M. A.; Franko, N. M.; Logue, J. K.; Mazzitelli, I. G.; Tiles, S. W.; Ahmed, K.; Shariq, A.; Snell, G.; Iqbal, N. T.; Geffner, J.; Bandera, A.; Gori, A.; Grifantini, R.; Chu, H. Y.; Van Voorhis, W. C.; Corti, D.; Veesler, D.
10.1101/2021.12.19.473391 — immunology — Posted on 2021-12-21
1162 Extrasynaptic signaling enables an asymmetric juvenile motor circuit to produce a symmetric gait
Lu, Y.; Ahamed, T.; Mulcahy, B.; Witvliet, D.; Guan, S. A.; Holmyard, D.; Hung, W.; Meng, J.; Wen, Q.; Chisholm, A.; Samuel, A.; Zhen, M.
10.1101/2021.09.21.461278 — neuroscience — Posted on 2021-12-21
1165 Multi-omics subtyping of hepatocellular carcinoma patients using a Bayesian network mixture model
Suter, P.; Dazert, E.; Kuipers, J.; Ng, C. K. Y.; Boldanova, T.; Hall, M. N.; Heim, M. H.; Beerenwinkel, N.
10.1101/2021.12.16.473083 — systems biology — Posted on 2021-12-21
1167 Arsenal of Nanobodies for Broad-Spectrum Countermeasures against Current and Future SARS-CoV-2 Variants of Concerns
Rossotti, M. A.; van Faassen, H.; Tran, A.; Sheff, J.; Sandhu, J. A.; Duque, D.; Hewitt, M.; Wen, S.; Bavananthasivam, R.; Beitari, S.; Matte, K.; Laroche, G.; Giguere, P. M.; Gervais, C.; Stuible, M.; Guimond, J.; Perret, S.; Hussack, G.; Langlois, M.-A.; Durocher, Y.; Tanha, J.
10.1101/2021.12.20.473401 — bioengineering — Posted on 2021-12-21
1168 The P3 O-Tert-Butyl-Threonine is Key to High Cellular and Antiviral Potency for Aldehyde-Based SARS-CoV-2 Main Protease Inhibitors
Ma, Y.; Yang, K.; Geng, Z. Z.; Alugubellia, Y. R.; Shaabani, N.; Vatansever, E. C.; Ma, X. R.; Cho, C.-C.; Khatua, K.; Blankenship, L.; Yu, G.; Sankaran, B.; Li, P.; Allen, R.; Ji, H.; Xu, S.; Liu, W. R.
10.1101/2021.12.18.473326 — biochemistry — Posted on 2021-12-21
1169 SARS-CoV-2 Omicron Variant: ACE2 Binding, Cryo-EM Structure of Spike Protein-ACE2 Complex and Antibody Evasion
Mannar, D.; Saville, J. W.; Zhu, X.; Srivastava, S. S.; Berezuk, A. M.; Tuttle, K.; Marquez, C.; Sekirov, I.; Subramaniam, S.
10.1101/2021.12.19.473380 — biochemistry — Posted on 2021-12-21
1170 Neuro-molecular characterization of fish cleaning interactions
Ramirez-Calero, S.; Paula, J. R.; Otjacques, E.; Rosa, R.; Ravasi, T.; Schunter, C.
10.1101/2021.06.22.449532 — animal behavior and cognition — Posted on 2021-12-21
1172 SARS-CoV-2 Omicron spike mediated immune escape, infectivity and cell-cell fusion
Meng, B.; Ferreira, I.; Abdullahi, A.; Kemp, S. A.; Goonawardane, N.; Papa, G.; Fatihi, S.; Charles, O.; Collier, D.; CITIID-NIHR BioResource COVID-19 Collaboration, ; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Choi, J.; Hyeon Lee, J.; Mlcochova, P.; James, L.; Doffinger, R.; Thukral, L.; Sato, K.; Gupta, R. K.
10.1101/2021.12.17.473248 — microbiology — Posted on 2021-12-21
1173 A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors
Chen, K.-Y.; Krischuns, T.; Ortega Varga, L.; Harigua-Souiai, E.; Paisant, S.; Zettor, A.; Chiaravalli, J.; Courtney, D.; O'Brien, A.; Baker, S.; Isel, C.; Agou, F.; Jacob, Y.; Blondel, A.; Naffakh, N.
10.1101/2021.12.18.473303 — microbiology — Posted on 2021-12-21
1175 OligoTRAFTACs: A Generalizable Method for Transcription Factor Degradation
Samarasinghe, K. T. G.; An, E.; Genuth, M.; Chu, L.; Holley, S.; Crews, C. M. M.
10.1101/2021.12.20.473482 — cancer biology — Posted on 2021-12-21
1182 Eukaryotic translation initiation factor eIF4E-5 is required for spermiogenesis in Drosophila melanogaster
Shao, L.; Fingerhut, J. M.; Falk, B. L.; Han, H.; Maldonado, G.; Qiao, Y.; Lee, V.; Hall, E.; Chen, L.; Polevoy, G.; Hernandez, G.; Lasko, P.; Brill, J. A.
10.1101/2021.12.19.473358 — developmental biology — Posted on 2021-12-20
1184 Single-molecule imaging reveals distinct effects of ligands on CCR5 dynamics depending on its dimerization status
Momboisse, F.; Nardi, G.; Colin, P.; Hery, M.; Cordeiro, N.; Schwartz, O.; Sauvonnet, N.; Arenzana-Seisdedos, F.; Lagache, T.; Lagane, B.; Olivo-Marin, J.-C.; Brelot, A.
10.1101/2021.12.20.473455 — cell biology — Posted on 2021-12-20
1185 Proteasome-dependent truncation of the negative heterochromatin regulator Epe1 mediates antifungal resistance
Yaseen, I.; White, S. A.; Torres-Garcia, S.; Spanos, C.; Lafos, M.; Gaberdiel, E.; Yeboah, R.; El Karouri, M.; Rappsilber, J.; Pidoux, A. L.; Allshire, R. C.
10.1101/2021.12.20.473483 — cell biology — Posted on 2021-12-20
1186 Neonatal enthesis healing involves non-inflammatory formation of acellular scar through ECM secretion by resident cells
Vinestock, R. C.; Felsenthal, N.; Assaraf, E.; Katz, E.; Rubin, S.; Heinemann-Yerushalmi, L.; Krief, S.; Dezorella, N.; Levin-Zaidman, S.; Tsoory, M.; Thomopoulos, S.; Zelzer, E.
10.1101/2021.12.20.473454 — molecular biology — Posted on 2021-12-20
1188 Defective proinsulin handling modulates the MHC I bound peptidome and activates the inflammasome in β-cells
Khilji, M. S.; Pinheiro-Machado, E.; Dahlby, T.; Aranha, R.; Buus, S.; Nielsen, M.; Klusek, J.; Faridi, P.; Purcell, A. W.; Mandrup-Poulsen, T.; Marzec, M. T.
10.1101/2021.12.20.472059 — molecular biology — Posted on 2021-12-20
1189 TSC22D4 interacts with Akt1 in response metabolic and stress signals
Demir, S.; Wolff, G.; Wieder, A.; Maida, A.; Rahm, M.; Schnoelzer, M.; Helm, D.; Hauck, S.; Szendroedi, J.; Herzig, S.; Uestuenel, B. E.
10.1101/2021.12.20.473554 — molecular biology — Posted on 2021-12-20
1192 Visualizing pyrazinamide action by live single cell imaging of phagosome acidification and Mycobacterium tuberculosis pH homeostasis
Santucci, P.; Aylan, B.; Botella, L.; Bernard, E. M.; Bussi, C.; Pellegrino, E.; Athanasiadi, N.; Gutierrez, M. G.
10.1101/2021.12.20.473466 — microbiology — Posted on 2021-12-20
1194 Re-evaluation of the phylogenetic diversity and global distribution of the genus Candidatus Accumulibacter
Petriglieri, F.; Singleton, C.; Kondrotaite, Z.; Dueholm, M. K. D.; McDaniel, E. A.; McMahon, K. D.; Nielsen, P. H.
10.1101/2021.12.20.473458 — microbiology — Posted on 2021-12-20
1195 ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection
Ching, K. L.; de Vries, M.; Gago, J.; Dancel-Manning, K.; Sall, J.; Rice, W. J.; Barnett, C.; Liang, F.-X.; Thorpe, L. E.; Shopsin, B.; Segal, L. N.; Dittmann, M.; Torres, V. J.; Cadwell, K.
10.1101/2021.12.17.473223 — immunology — Posted on 2021-12-20
1196 Evidence for a Potential Pre-Pandemic SARS-like Coronavirus Among Animals in North America
Hancock, T. J.; Hickman, P.; Kazerooni, N.; Kennedy, M.; Kania, S. A.; Dennis, M.; Szafranski, N.; Gerhold, R. W.; Su, C.; Masi, T. J.; Smith, S.; Sparer, T. E.
10.1101/2021.12.17.473265 — immunology — Posted on 2021-12-20
1197 Synthetic lethal screening identifies existing drugs with selective viability effects on Neurofibromatosis type-1 model systems
Wang, Y.; Stevens, M.; Mandigo, T. R.; Bouley, S. J.; Sharma, A.; Sengupta, S.; Housden, A. E.; Perrimon, N.; Walker, J. A.; Housden, B. E.
10.1101/2021.12.20.473481 — cancer biology — Posted on 2021-12-20
1199 A Computational Dissection of Spike protein of SARS-CoV-2 Omicron Variant
Rehman, Z.; Umair, M.; Ikram, A.; Salman, M.; Haider, S. A.; Ammar, M.
10.1101/2021.12.17.473260 — bioinformatics — Posted on 2021-12-20
1200 Protein folding stabilities are a major determinant of oxidation rates for buried methionine residues
Walker, E. J.; Bettinger, J. Q.; Welle, K. A.; Hryhorenko, J. R.; Vargas, A. M. M.; O'Connell, M. R.; Ghaemmaghami, S.
10.1101/2021.12.20.473526 — biochemistry — Posted on 2021-12-20
1201 O-methylated N-glycans Distinguish Mosses from Vascular Plants
Stenitzer, D.; Mocsai, R.; Zechmeister, H.; Reski, R.; Decker, E. L.; Altmann, F.
10.1101/2021.12.20.473427 — biochemistry — Posted on 2021-12-20
1202 DEAD-box RNA Helicases Act as Nucleotide Exchange Factors for Casein Kinase 2
Fatti, E.; Hirth, A.; Svorinic, A.; Guenther, M.; Cruciat, C.-M.; Stier, G.; Acebron, S. P.; Papageorgiou, D.; Sinning, I.; Krijgsveld, J.; Hoefer, T.; Niehrs, C.
10.1101/2021.12.20.473452 — biochemistry — Posted on 2021-12-20
1206 Unraveling the antiviral activity of plitidepsin by subcellular and morphological analysis
Sachse, M.; Tenorio, R.; Fernandez de Castro, I.; Munoz-Basagoiti, J.; Perez-Zsolt, D.; Raich-Regue, D.; Rodo, J.; Losada, A.; Aviles, P.; Cuevas, C.; Paredes, R.; Segales, J.; Clotet, B.; Vergara-Alert, J.; Izquierdo-Useros, N.; Risco, C.
10.1101/2021.12.16.472880 — microbiology — Posted on 2021-12-20
1207 A tRNA-acetylating toxin and detoxifying enzyme in Mycobacterium tuberculosis.
Tomasi, F. G.; Hall, A. M. J.; Schweber, J. T. P.; Dulberger, C. L.; McGowen, K.; Liu, Q.; Fortune, S. M.; Helaine, S.; Rubin, E. J.
10.1101/2021.12.20.473312 — microbiology — Posted on 2021-12-20
1208 Antiviral RNAi response against the insect-specific Agua Salud alphavirus
Altinli, M.; Leggewie, M.; Badusche, M.; Gyanwali, R.; Scherer, C.; Schulze, J.; Vattipally, S.; Fegebank, M.; Zibrat, B.; Fuss, J.; Junglen, S.; Schnettler, E.
10.1101/2021.12.20.473494 — microbiology — Posted on 2021-12-20
1209 Vandetanib Reduces Inflammatory Cytokines and Ameliorates COVID-19 in Infected Mice
Puhl, A. C.; Gomes, G. F.; Damasceno, S.; Fritch, E. J.; Levi, J. A.; Johnson, N. J.; Scholle, F.; Premkumar, L.; Hurst, B. L.; LeeMontiel, F.; Veras, F. P.; Batah, S. S.; Fabro, A. T.; Moorman, N. J.; Yount, B.; Dickmander, R.; Baric, R. S.; Pearce, K. H.; Cunha, F.; Alves-Filho, J. C.; Cunha, T.; Ekins, S.
10.1101/2021.12.16.472155 — immunology — Posted on 2021-12-20
1211 Variable loss of antibody potency against SARS-CoV-2 B.1.1.529 (Omicron)
Sheward, D. J.; Kim, C.; Ehling, R. A.; Pankow, A.; Castro Dopico, X.; Martin, D. P.; Reddy, S. T.; Dillner, J.; Karlsson Hedestam, G. B.; Albert, J.; Murrell, B.
10.1101/2021.12.19.473354 — immunology — Posted on 2021-12-20
1212 Neutrophil Profiles of Pediatric COVID-19 and Multisystem Inflammatory Syndrome in Children
Boribong, B. P.; LaSalle, T. J.; Bartsch, Y. C.; Ellett, F.; Loiselle, M. E.; Davis, J. P.; Gonye, A. L. K.; Hajizadeh, S.; Kreuzer, J.; Pillai, S.; Haas, W.; Edlow, A. G.; Fasano, A.; Alter, G.; Irimia, D.; Sade-Feldman, M.; Yonker, L. M.
10.1101/2021.12.18.473308 — immunology — Posted on 2021-12-20
1213 The MLL3/4 complexes and MiDAC act antagonistically as genome-wide regulators of H4K20ac to control a specific gene expression program
Wang, X.; Rosikiewicz, W.; Sedkov, Y.; Mondal, B.; Kallappagoudar, S.; Tvardovskiy, A.; Bajpai, R.; Xu, B.; Pruett-Miller, S. M.; Schneider, R.; Herz, H.-M.
10.1101/2021.12.17.473155 — molecular biology — Posted on 2021-12-20
1214 Conformational rearrangements upon start codon recognition in human 48S translation initiation complex
Yi, S.-H.; Petrychenko, V.; Schliep, J. E.; Goyal, A.; Linden, A.; Chari, A.; Urlaub, H.; Stark, H.; Rodnina, M. V.; Adio, S.; Fischer, N.
10.1101/2021.12.17.473132 — molecular biology — Posted on 2021-12-20
1215 Engineering selectivity of Cutibacterium acnes phages by epigenetic imprinting
Knoedlseder, N.; Nevot, G.; Fabrega, M.; Mir-Pedrol, J.; Sanvicente, M.; Güell, M.
10.1101/2021.12.19.473365 — microbiology — Posted on 2021-12-20
1216 Modeling osteoporosis to design and optimize pharmacologic therapies comprising multiple drug types
Jörg, D. J.; Fuertinger, D. H.; Cherif, A.; Bushinsky, D. A.; Mermelstein, A.; Raimann, J. G.; Kotanko, P.
10.1101/2021.12.17.473190 — pharmacology and toxicology — Posted on 2021-12-20
1217 Haplotype-resolved inversion landscape reveals hotspots of mutational recurrence associated with genomic disorders
Porubsky, D.; Höps, W.; Ashraf, H.; Hsieh, P.; Rodriguez-Martin, B.; Yilmaz, F.; Ebler, J.; Hallast, P.; Maggiolini, F. A. M.; Harvey, W. T.; Henning, B.; Audano, P. A.; Gordon, D. S.; Ebert, P.; Hasenfeld, P.; Benito, E.; Zhu, Q.; Human Genome Structural Variation Consortium, ; Lee, C.; Antonacci, F.; Steinrücken, M.; Beck, C. R.; Sanders, A. D.; Marschall, T.; Eichler, E. E.; Korbel, J. O.
10.1101/2021.12.20.472354 — genomics — Posted on 2021-12-20
1219 The transcriptional hallmarks of intra-tumor heterogeneity across a thousand tumors
Gavish, A.; Tyler, M.; Simkin, D.; Kovarsky, D.; Gonzalez Castro, L. N.; Halder, D.; Chanoch-Myers, R.; Laffy, J.; Mints, M.; Greenwald, A. R.; Weider, A.; Tal, R.; Spitzer, A.; Hara, T.; Tirosh, A.; Puram, S. V.; Suva, M. L.; Tirosh, I.
10.1101/2021.12.19.473368 — cancer biology — Posted on 2021-12-20
1220 Mapping pediatric brain tumors to their origins in the developing cerebellum
Okonechnikov, K.; Joshi, P.; Sepp, M.; Leiss, K.; Sarropoulos, I.; Murat, F.; Sill, M.; Beck, P.; Chan, K. C.-H.; Korshunov, A.; Sahm, F.; Deng, M. Y.; Sturm, D.; DeSisto, J.; Donson, A. M.; Foreman, N. K.; Green, A. L.; Robinson, G.; Orr, B. A.; Gao, Q.; Darrow, E.; Hadley, J. L.; Northcott, P. A.; Gojo, J.; Ryzhova, M.; Kawauchi, D.; Hovestadt, V.; Filbin, M. G.; von Deimling, A.; Zuckermann, M.; Pajtler, K. W.; Kool, M.; Jones, D. T. W.; Jager, N.; Kutscher, L. M.; Kaessmann, H.; Pfister, S. M.
10.1101/2021.12.19.473154 — cancer biology — Posted on 2021-12-20
1224 Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift
Cameroni, E.; Saliba, C.; Bowen, J. E.; Rosen, L. E.; Culap, K.; Pinto, D.; VanBlargan, L. A.; De Marco, A.; Zepeda, S. K.; di Iulio, J.; Zatta, F.; Kaiser, H.; Noack, J.; Farhat, N.; Czudnochowski, N.; Havenar-Daughton, C.; Sprouse, K. R.; Dillen, J. R.; Powell, A. E.; Chen, A.; Maher, C.; Yin, L.; Sun, D.; Soriaga, L.; Bassi, J.; Silacci-Fregni, C.; Gustafsson, C.; Chu, H.; Franko, N. M.; Logue, J.; Iqbal, N. T.; Mazzitelli, I.; Geffner, J.; Grifantini, R.; Gori, A.; Riva, A.; Giannini, O.; Ceschi, A.; Ferrari, P.; Franzetti-Pellanda, A.; Garzoni, C.; Halfmann, P.; Kawaoka, Y.; Hebner, C.; P
10.1101/2021.12.12.472269 — immunology — Posted on 2021-12-20
1225 Automatic Detection and Neurotransmitter Prediction of Synapses in Electron Microscopy
Zhang, A.; Shailja, S.; Borba, C.; Miao, Y.; Goebel, M.; Ruschel, R.; Ryan, K.; Smith, W.; Manjunath, B. S.
10.1101/2021.11.02.467022 — neuroscience — Posted on 2021-12-20
1228 Pre-clinical evaluation of antiviral activity of nitazoxanide against Sars-CoV-2
Driouich, J.-S.; Cochin, M.; Touret, F.; Petit, P.-R.; Gilles, M.; Moureau, G.; Barthelemy, K.; Laprie, C.; Wattanakul, T.; Chotsiri, P.; Hoglund, R. M.; Tarning, J.; Escudie, F.; Scandale, I.; Chatelain, E.; de Lamballerie, X.; Solas, C.; Nougairede, A.
10.1101/2021.12.17.473113 — pathology — Posted on 2021-12-20
1230 Structure prediction of the druggable fragments in SARS-CoV-2 untranslated regions
Gumna, J.; Antczak, M.; Adamiak, R. W.; Bujnicki, J. M.; Chen, S.-J.; Ding, F.; Ghosh, P.; Li, J.; Mukherjee, S.; Nithin, C.; Pachulska-Wieczorek, K.; Ponce-Salvatierra, A.; Popenda, M.; Sarzynska, J.; Wirecki, T.; Zhang, D.; Zhang, S.; Zok, T.; Westhof, E.; Szachniuk, M.; Miao, Z.; Rybarczyk, A.
10.1101/2021.12.17.473170 — bioinformatics — Posted on 2021-12-20
1232 Emerging SARS-CoV-2 Variants of Concern: Spike Protein Mutational Analysis and Epitope for Broad Neutralization
Mannar, D.; Saville, J. W.; Sun, Z.; Zhu, X.; Marti, M. M.; Srivastava, S. S.; Berezuk, A. M.; Zhou, S.; Tuttle, K.; Sobolewski, M. D.; Kim, A.; Treat, B. R.; Mayrelle Da Silva Castanha, P.; Jacobs, J. L.; Barratt-Boyes, S. M.; Mellors, J. W.; Dimiter, D. S.; Li, W.; Subramaniam, S.
10.1101/2021.12.17.473178 — biochemistry — Posted on 2021-12-20
1234 Insights into standards of care: dexamethasone and antibodies against COVID-19 in hamster models
Wyler, E.; Adler, J. M.; Eschke, K.; Teixeira Alves, G.; Peidli, S.; Pott, F.; Kazmierski, J.; Michalik, L.; Kershaw, O.; Bushe, J.; Andreotti, S.; Pennitz, P.; Abdelgawad, A.; Postmus, D.; Goffinet, C.; Kreye, J.; Reincke, S. M.; Prüss, H.; Blüthgen, N.; Gruber, A. D.; Kuebler, W. M.; Witzenrath, M.; Landthaler, M.; Nouailles, G.; Trimpert, J.
10.1101/2021.12.17.473180 — molecular biology — Posted on 2021-12-20
1235 Disrupted Peyer's patch microanatomy in COVID-19 including germinal centre atrophy independent of local virus
Trevelin, S. C.; Pickering, S.; Todd, K.; Bishop, C.; Pitcher, M.; Mesa, J. G.; Montorsi, L.; Spada, F.; Petrov, N.; Green, A.; Shankar-Hari, M.; Neil, S. J. D.; Spencer, J.
10.1101/2021.12.17.473179 — immunology — Posted on 2021-12-20
1238 Detection of antimicrobial resistance, pathogenicity, and virulence potentials of non-typhoidal Salmonella isolates at the Yaounde abattoir using whole genome sequencing technique
Matchawe, C.; Machuka, E. M.; Kyalo, M.; Bonny, P.; Gerard, N.; Njaci, I.; Esemu, S. N.; Githae, D.; Juma, J.; Bawe, M.; Nsawir, B. J.; Piasentier, E.; Ndip, L. M.; Pelle, R.
10.1101/2021.12.15.472740 — microbiology — Posted on 2021-12-20
1239 A neuronal prospect theory model in the brain reward circuitry
Imaizumi, Y.; Tymula, A.; Tsubo, Y.; Matsumoto, M.; Yamada, H.
10.1101/2021.12.18.473272 — neuroscience — Posted on 2021-12-20
1242 Global cerebrospinal fluid circulation mapping using gold nanoparticle enhanced X-ray microtomography reveals region-specific brain and spinal cord CSF pathways
Pan, S.; DeFreitas, D.; Ramagiri, S.; Bayguinov, P.; Hacker, C. D.; Snyder, A. Z.; Wilborn, J.; Huang, H.; Yang, P. H.; Raval, D. K.; Sviben, S.; Achilefu, S.; Tang, R.; Haller, G.; Quirk, J. D.; Fitzpatrick, J. A.; Esakky, P.; Strahle, J.
10.1101/2021.12.18.473250 — neuroscience — Posted on 2021-12-20
1244 An Agent-Based Model of monocyte differentiation into Tumour-Associated Macrophages in Chronic Lymphocytic Leukemia
Verstraete, N.; Marku, M.; Domagala, M.; Bordenave, J.; Arduin, H.; FOURNIE, j. j.; Ysebaert, L.; Poupot, M.; Pancaldi, V.
10.1101/2021.12.17.473137 — systems biology — Posted on 2021-12-20
1245 Rapid profiling of protein complex re-organization in perturbed systems
Bludau, I.; Nicod, C.; Martelli, C.; Xue, P.; Heusel, M.; Fossati, A.; Uliana, F.; Frommelt, F.; Aebersold, R.; Collins, B. C.
10.1101/2021.12.17.473177 — systems biology — Posted on 2021-12-20
1246 Temporal in vivo platelet labelling in mice reveals age-dependent receptor expression and conservation of specific mRNAs
Armstrong, P. C.; Allan, H. E.; Kirkby, N. S.; Joshi, A.; Gutmann, C.; Crescente, M.; Mitchell, J. A.; Mayr, M.; Warner, T. D.
10.1101/2021.12.17.473131 — physiology — Posted on 2021-12-20
1247 Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function
Wolff, G.; Sakurai, M.; Mhamane, A.; Maida, A.; Deligiannis, I. K.; Yin, K.; Weber, P.; Weider, A.; Troullinaki, M.; Zeigerer, A.; Roden, M.; Volk, N.; Poth, T.; Hackert, T.; Wiedmann, L.; Rigotti, F. D. A.; Rodriguez-Vita, J.; Fischer, A.; Mukthavaram, R.; Limphong, P.; Tachikawa, K.; Karmali, P.; Payne, J.; Chivukula, P.; Ekim-Uestuenel, B.; Martinez-Jimenez, C. P.; Szendroedi, J.; Nawroth, P.; Herzig, S.
10.1101/2021.12.17.473222 — physiology — Posted on 2021-12-20
1248 Lipid hydroperoxides promote muscle atrophy through lysosomal amplification
Eshima, H.; Siripoksup, P.; Shahtout, J. L.; Pearson, M. J.; Mahmassani, Z. S.; Ferrara, P. J.; Lyons, A. W.; Maschek, J. A.; Peterlin, A. D.; Verkerke, A. R. P.; Johnson, J. M.; Salcedo, A.; Petrocelli, J. J.; Anderson, E. J.; Boudina, S.; Ran, Q.; Cox, J. E.; Drummond, M. J.; Funai, K.
10.1101/2021.12.17.473200 — physiology — Posted on 2021-12-20
1249 Air Pollution Particles Hijack Peroxidasin to Disrupt Immunosurveillance and Promote Lung Cancer
Wang, Z.; Zhai, Z.; Chen, C.; Tian, X.; Xing, Z.; Xing, P.; Yang, Y.; Zhang, J.; Wang, C.; Dong, L.
10.1101/2021.12.17.473156 — cancer biology — Posted on 2021-12-20
1252 Optimal operation of parallel mini-bioreactors in bioprocess development using multi-stage MPC
Krausch, N.; Kim, J. W.; Lucia, S.; Gross, S.; Barz, T.; Neubauer, P.; Cruz Bournazou, M. N.
10.1101/2021.12.17.472671 — bioengineering — Posted on 2021-12-20
1255 Diversity and Divergence: Evolution of defense chemistry in the tropical tree genus Inga
Forrister, D. L.; Endara, M.-J.; Soule, A. J.; Younkin, G. C.; Mills, A. G.; Lokvam, J.; Dexter, K. G.; Pennington, R. T.; Kidner, C. A.; Nichols, J. A.; Loiseau, O.; Kursar, T. A.; Coley, P. D.
10.1101/2021.12.17.473194 — evolutionary biology — Posted on 2021-12-20
1256 The interaction of climate history and evolution impacts alpine biodiversity assembly differently in freshwater and on land
Jardim-deQueiroz, L.; Doenz, C. J.; Altermatt, F.; Alther, R.; Borko, S.; Gossner, M. M.; Graham, C.; Matthews, B.; McFadden, I. R.; Pellissier, L.; Schmitt, T.; Selz, O. M.; Villalba, S.; Rüber, L.; Zimmermann, N.; Seehausen, O.
10.1101/2021.12.17.472935 — evolutionary biology — Posted on 2021-12-20
1257 "Heat waves" experienced during larval life have species-specific consequences on life-history traits and sexual development in anuran amphibians
Ujszegi, J.; Bertalan, R.; Ujhegyi, N.; Verebelyi, V.; Nemeshazi, E.; Miko, Z.; Kasler, A.; Herczeg, D.; Szederkenyi, M.; Vili, N.; Gal, Z.; Hoffmann, O. I.; Bokony, V.; Hettyey, A.
10.1101/2021.12.17.473144 — ecology — Posted on 2021-12-20
1259 Recall of B cell memory depends on relative locations of prime and boost
Kuraoka, M.; Yeh, C.-H.; Bajic, G.; Kotaki, R.; Song, S.; Harrison, S. C.; Kelsoe, G.
10.1101/2021.12.17.472609 — immunology — Posted on 2021-12-20
1260 ILC homeostasis phenotyping in various tissues, aging, and sex differences
Mobley, A. S.; Bautista Garrido, J. J.; Honarpisheh, P.; d'Aigle, J.; McCullough, L. D.; Aronowski, J.
10.1101/2021.12.17.473226 — immunology — Posted on 2021-12-20
1261 Targeting macrophages with CAR-T cells delays solid tumor progression and enhances anti-tumor immunity
Sanchez-Paulete, A. R.; Mateus-Tique, J.; Mollaoglu, G.; Nielsen, S. R.; Marks, A.; Lakshmi, A.; Pia, L.; Baccarini, A.; Merad, M.; Brown, B. D.
10.1101/2021.12.17.473184 — immunology — Posted on 2021-12-20
1263 Mesoscale cortex-wide neural dynamics predict self-initiated actions in mice several seconds prior to movement
Mitelut, C.; Zhang, Y.; Sekino, Y.; Boyd, J.; Bolanos, F.; Swindale, N. V.; Silasi, G.; Saxena, S.; Murphy, T. H.
10.1101/2021.12.17.473193 — neuroscience — Posted on 2021-12-20
1266 Efficient Design Of Peptide-Binding Polymers Using Active Learning Approaches
Rakhimbekova, A.; Lopukhov, A.; Klyachko, N. L.; Kabanov, A.; Madzhidov, T. I.; Tropsha, A.
10.1101/2021.12.17.473241 — pharmacology and toxicology — Posted on 2021-12-20
1267 MicroRNA-like snoRNA-derived RNAs (sdRNAs) promote castration resistant prostate cancer
Coley, A. B.; Stahly, A. N.; Kasukurthi, M. V.; Barchie, A. A.; Hutcheson, S. B.; Houserova, D.; Huang, Y.; Watters, B. C.; King, V. M.; Dean, M. A.; Roberts, J. T.; DeMeis, J. D.; McInnis, C. H.; Godang, N. L.; Wright, R. M.; Haider, D. F.; Piracha, N. B.; Brown, C. L.; Ijaz, Z. M.; Li, S.; Xi, Y.; McDonald, O. G.; Huang, J.; Borchert, G. M.
10.1101/2021.12.17.473174 — cancer biology — Posted on 2021-12-20
1272 Unexpected arabinosylation after humanization of plant protein N-glycosylation
Bohlender, L. L.; Parsons, J.; Hoernstein, S. N. W.; Bangert, N.; Rodriguez-Jahnke, F.; Reski, R.; Decker, E. L.
10.1101/2021.12.17.473187 — bioengineering — Posted on 2021-12-20
1275 Structure of Vibrio phage XM1, a simple contractile DNA injection machine
Wang, Z.; Fokine, A.; Guo, X.; Jiang, W.; Rossmann, M. G.; Kuhn, R. J.; Luo, Z.-H.; Klose, T.
10.1101/2021.12.18.469577 — molecular biology — Posted on 2021-12-20
1277 Rec8 cohesin-mediated loop-axis chromatin architecture is required for meiotic recombination
Sakuno, T.; Tashiro, S.; Tanizawa, H.; Iwasaki, O.; Ding, D.-Q.; Haraguchi, T.; Noma, K.-i.; Hiraoka, Y.
10.1101/2021.12.09.472021 — cell biology — Posted on 2021-12-20
1280 A comprehensive LFQ benchmark dataset on modern day acquisition strategies in proteomics
Van Puyvelde, B.; Daled, S.; Willems, S.; Gabriels, R.; Gonzalez de Peredo, A.; Chaoui, K.; Mouton-Barbosa, E.; Bouyssie, D.; Boonen, K.; Hughes, C.; Gethings, L.; Perez-Riverol, Y.; Bloomfield, N.; Tate, S.; Schiltz, O.; Martens, L.; Deforce, D.; Dhaenens, M.
10.1101/2021.11.24.469852 — bioinformatics — Posted on 2021-12-20
1282 Neutralization and Stability of SARS-CoV-2 Omicron Variant
Cong, Z.; Evans, J. P.; Qu, P.; Faraone, J.; Zheng, Y.-M.; Carlin, C.; Bednash, J. S.; Zhou, T.; Lozanski, G.; Mallampalli, R.; Saif, L. J.; Oltz, E. M.; Mohler, P.; Xu, K.; Gumina, R. J.; Liu, S.-L.
10.1101/2021.12.16.472934 — microbiology — Posted on 2021-12-20
1283 Changes of small non-coding RNAs by severe acute respiratory syndrome coronavirus 2 infection
Wu, W.; Choi, E.-J.; Wang, B.; Zhang, K.; Adam, A.; Huang, G.; Tunkle, L.; Huang, P.; Goru, R.; Imirowicz, I.; Henry, L.; Lee, I.; Dong, J.; Wang, T.; Bao, X.
10.1101/2021.12.16.472982 — microbiology — Posted on 2021-12-20
1285 Reduced sera neutralization to Omicron SARS-CoV-2 by bothinactivated and protein subunit vaccines and the convalescents
Zhao, X.; Li, D.; Ruan, W.; Zhang, R.; Zheng, A.; Qiao, S.; Zheng, X.; Zhao, Y.; Chen, Z.; Dai, L.; Han, P.; Gao, G. F.
10.1101/2021.12.16.472391 — immunology — Posted on 2021-12-20
1286 The T cell receptor repertoire reflects the dynamics of the immune response to vaccination
Mohammed, K.; Meadows, A.; Hatem, S.; Hekmaty, S.; Simon, V.; Jayaprakash, A. D.; Sachidanandam, R.
10.1101/2021.12.09.471735 — immunology — Posted on 2021-12-19
1287 Molecular identification of bats from Wavulgalge cave, Wellawaya, Sri Lanka
Perera, T.; Schwarz, F.; Muzeniek, T.; Siriwardana, S.; Becker-Ziaja, B.; Perera, I.; Handunnetti, S.; Weerasena, J.; Premawansa, G.; Premawansa, S.; Nitsche, A.; Yapa, W.; Kohl, C.
10.1101/2021.12.19.473364 — zoology — Posted on 2021-12-19
1288 The Skeletal Muscle Circadian Clock Regulates Titin Splicing Through RBM20
Riley, L.; Zhang, X.; Mijares, J.; Hammers, D.; Wolff, C. A.; Wood, N. B.; Olafson, H.; Du, P.; Douglas, C.; Previs, M. J.; Labeit, S.; T. Wang, E.; Esser, K. A.
10.1101/2021.05.27.445953 — physiology — Posted on 2021-12-19
1290 Extending and using anatomical vocabularies in the Stimulating Peripheral Activity to Relieve Conditions (SPARC) program
Surles-Zeigler, M. C.; Sincomb, T.; Gillespie, T. H.; de Bono, B.; Bresnahan, J.; Mawe, G. M.; Grethe, J. S.; Tappan, S.; Heal, M.; Martone, M. E.
10.1101/2021.11.15.467961 — bioinformatics — Posted on 2021-12-19
1293 Response of Surface Water Quality Characteristics to Socio-economic Factors in Eastern-Central China
Duan, M.; Zhang, S.; He, J.; Xu, M.; Gao, Y.; Zhang, J.; Shilu Zhang, Mingxia Xu, Junyu He, Yuanyuan Gao, Jun Zhang,
10.1101/2021.12.19.473363 — biochemistry — Posted on 2021-12-19
1295 RNAi screen of RING/U-box domain ubiquitin ligases identifies critical regulators of tissue regeneration in planarians
Allen, J. M.; Balagtas, M.; Barajas, E.; Cano Macip, C.; Alvarez Zepeda, S.; Iberkleid, I.; Duncan, E. M.; Zayas, R. M.
10.1101/2021.10.12.463740 — developmental biology — Posted on 2021-12-19
1296 SufB intein splicing in Mycobacterium tuberculosis is influenced by two remote conserved N-extein Histidines
Panda, S.; Nanda, A.; Sahu, N.; Ojha, D. K.; Pradhan, B.; Rai, A.; Suryawanshi, A. R.; Banavali, N.; Nayak, S.
10.1101/2021.07.07.451452 — molecular biology — Posted on 2021-12-19
1297 CD4 T cells are rapidly depleted from tuberculosis granulomas following acute SIV co-infection
Foreman, T. W.; Nelson, C. E.; Kauffman, K. D.; Lora, N. E.; Vinhaes, C. L.; Dorosky, D. E.; Sakai, S. W.; Gomez, F.; Fleegle, J. D.; Parham, M.; Perera, S. R.; Lindestam Arlehamn, C. S.; Sette, A.; Tuberculosis Imaging Program, ; Brenchley, J. M.; Queiroz, A.; Andrade, B. B.; Kabat, J.; Via, L. E.; Barber, D. L.
10.1101/2021.12.17.473203 — immunology — Posted on 2021-12-19
1298 An effective workshop on How to be an Effective Mentor for Underrepresented STEM Trainees
Marshall, A.; Vue, Z.; Palavicino-Maggio, C.; Spencer, E. C.; Beasley, H. K.; Garza Lopez, E.; Conley, Z.; Neikirk, K.; Murray, S. A.; Martinez, D.; Davis, J.; Brady, L.; Shuler, H. D.; Morton, D.; Hinton, A.
10.1101/2021.12.06.471498 — scientific communication and education — Posted on 2021-12-19
1302 m6A demethylase ALKBH5 promotes tumor cell proliferation by destabilizing IGF2BPs target genes and worsens the prognosis of patients with non-small cell lung cancer
Tsuchiya, K.; Yoshimura, K.; Iwashita, Y.; Inoue, Y.; Ohta, T.; Watanabe, H.; Yamada, H.; Kawase, A.; Tanahashi, M.; Ogawa, H.; Funai, K.; Shinmura, K.; Suda, T.; Sugimura, H.
10.1101/2021.07.06.451216 — cancer biology — Posted on 2021-12-19
1306 Dynamics of the habitat use of three predatory freshwater fish in a lentic ecosystem
Riha, M.; Rabaneda-Bueno, R.; Jaric, I.; Souza, A. T.; Vejrik, L.; Drastik, V.; Blabolil, P.; Holubova, M.; Juza, T.; Gjelland, K.; Rychtecky, P.; Sajdlova, Z.; Kocvara, L.; Tuser, M.; Prchalova, M.; Seda, J.; Peterka, J.
10.1101/2021.12.16.471647 — ecology — Posted on 2021-12-19
1307 Sex-dependent effects of traumatic stress on social behavior and neuronal activation in the prefrontal cortex and amygdala
Dorofeikova, M.; Borkar, C. D.; Weissmuller, K.; Smith-Osborne, L.; Basavanhalli, S.; Bean, E.; Duong, A.; Resendez, A.; Fadok, J. P.
10.1101/2021.12.16.473017 — neuroscience — Posted on 2021-12-19
1309 Spontaneous Neuronal Oscillations in the Human Insula are Hierarchically Organized Traveling Waves
Das, A.; Myers, J.; Mathura, R.; Shofty, B.; Metzger, B. A.; Bijanki, K.; Wu, C.; Jacobs, J.; Sheth, S. A.
10.1101/2021.12.16.473034 — neuroscience — Posted on 2021-12-19
1313 Insights from the IronTract challenge: optimal methods for mapping brain pathways from multi-shell diffusion MRI
Maffei, C.; Girard, G.; Schilling, K.; Aydogan, B.; Aduluru, N.; Zhylka, A.; Wu, Y.; Mancini, M.; Hamamci, A.; Sarica, A.; Telliac, A.; Baete, S.; Karimi, D.; Yeh, F.; Yildiz, M.; Gholipour, A.; Bihan-Poudec, Y.; Hiba, B.; Quattrone, A.; Quattrone, A.; Boshkovski, T.; Stikov, N.; Yap, P.-T.; De Luca, A.; Pluim, J.; Leemans, A.; Prabhakaran, V.; Bendlin, B. B.; Alexander, A.; Landman, B.; Canales-Rodriguez, E.; Barakovic, M.; Rafael-Patino, J.; Yu, T.; Rensonnet, G.; Schiavi, S.; Daducci, A.; Pizzolato, M.; Fischi-Gomez, E.; Thiran, J.-P.; Dai, G.; Grisot, G.; Lazovski, N.; Puch, S.; Ramos, M.;
10.1101/2021.12.17.472836 — neuroscience — Posted on 2021-12-19
1314 Optimizing dosage-specific treatments in a multi-scale model of a tumor growth
Ponce-de-Leon, M.; Montagud, A.; Akasiadis, C.; Schreiber, J.; Ntiniakou, T.; Valencia, A.
10.1101/2021.12.17.473136 — systems biology — Posted on 2021-12-19
1315 Effects of anesthesia on ozone-induced lung and systemic inflammation
Wilson, M. L.; Thysell, J. A.; Baumann, K. K.; Quaranta, D. V.; Liang, W.-S. S.; Erickson, M. A.
10.1101/2021.12.16.472860 — physiology — Posted on 2021-12-19
1317 anndata: Annotated data
Virshup, I.; Rybakov, S.; Theis, F. J.; Angerer, P.; Wolf, F. A.
10.1101/2021.12.16.473007 — bioinformatics — Posted on 2021-12-19
1318 Deep metabolic profiling assessment of tissue extraction protocols for three model organisms
Gegner, H. M.; Mechtel, N.; Heidenreich, E.; Wirth, A.; Cortizo, F. G.; Bennewitz, K.; Fleming, T.; Andresen, C.; Freichel, M.; Teleman, A. A.; Kroll, J.; Hell, R.; Poschet, G.
10.1101/2021.12.16.472947 — biochemistry — Posted on 2021-12-19
1319 Skin resident memory cells generated by the L. major centrin gene deleted parasites mediate protective immune response analogous to leishmanization
Ismail, N.; Karmakar, S.; Bhattacharya, P.; Sepahpour, T.; Takeda, K.; Hamano, S.; Matlashewski, G.; Satoskar, A. R.; Gannavaram, S.; DEY, R.; Nakhasi, H. L.
10.1101/2021.12.17.472620 — immunology — Posted on 2021-12-19
1320 DeepMed: A unified, modular pipeline for end-to-end deep learning in computational pathology
van Treeck, M.; Cifci, D.; Ghaffari Laleh, N.; Saldanha, O. L.; Loeffler, C. M. L.; Hewitt, K. J.; Muti, H. S.; Echle, A.; Seibel, T.; Seraphin, T. P.; Trautwein, C.; Foersch, S.; Luedde, T.; Truhn, D.; Kather, J. N.
10.1101/2021.12.19.473344 — cancer biology — Posted on 2021-12-19
1325 Parent of origin DNA methylation as a potential mechanism for genomic imprinting in bees.
Marshall, H.; Nicholas, M. T.; van Zweden, J. S.; Wäckers, F.; Ross, L.; Wenseleers, T.; Mallon, E. B.
10.1101/2021.12.17.473163 — evolutionary biology — Posted on 2021-12-19
1326 Identification and characterization of BrxR as a regulatory gene in the BREX phage restriction system
Luyten, Y.; Hausman, D.; Young, J. C.; Doyle, L. A.; Ubilla-Rodriguez, N. C.; Lambert, A. R.; Arroyo, C.; Forsberg, K. J.; Morgan, R. D.; Stoddard, B. L.; Kaiser, B. K.
10.1101/2021.12.19.473356 — molecular biology — Posted on 2021-12-19
1328 A widespread family of WYL-domain transcriptional regulators co-localises with diverse phage defence systems and islands
Picton, D. M.; Harling-Lee, J. D.; Duffner, S. J.; Went, S. C.; Morgan, R. D.; Hinton, J. C. D.; Blower, T. R.
10.1101/2021.12.19.473342 — microbiology — Posted on 2021-12-19
1329 The Interferon Resistance of Transmitted HIV-1 is a Consequence of Enhanced Replicative Fitness
Sugrue, E.; Wickenhagen, A.; Mollentze, N.; Aziz, M. A.; Sreenu, V. B.; Truxa, S.; Tong, L.; da Silva Filipe, A.; Robertson, D. L.; Hughes, J.; Rihn, S. J.; Wilson, S. J.
10.1101/2021.12.18.473292 — microbiology — Posted on 2021-12-19
1330 Identification of CDRH3 Loops in the Naive B Cell Receptor Repertoire that Can Be Engaged by Candidate Immunogens
Swanson, O.; Beem, J. M.; Rhodes, B.; Wang, A.; Barr, M.; Chen, H.; Parks, R.; Saunders, K. O.; Haynes, B. F.; Wiehe, K.; Azoitei, M. L.
10.1101/2021.12.18.473225 — immunology — Posted on 2021-12-19
1333 Lonafarnib improves cardiovascular function and survival in a mouse model of Hutchinson-Gilford Progeria Syndrome
Murtada, S.-I.; Mikush, N.; Wang, M.; Ren, P.; Kawamura, Y.; Ramachandra, A. B.; Braddock, D. T.; Tellides, G.; Gordon, L. B.; Humphrey, J. D.
10.1101/2021.12.17.473197 — pathology — Posted on 2021-12-19
1337 Metabolic Processing of Selenium-based Bioisostere of meso-diaminopimelic Acid in Live Bacteria
Apostolos, A. J.; Koyasseril-Yehiya, T. M.; Santamaria, C.; Silva, J. R. A.; Lameira, J.; Alves, M. C.; Siegrist, M. S.; Pires, M. M.
10.1101/2021.12.18.472960 — microbiology — Posted on 2021-12-19
1339 DOK1 and DOK2 regulate CD8+ T cell signaling and memory formation without affecting tumor cell killing
Laletin, V.; Bernard, P.-L.; Camille, M.; Yamanashi, Y.; Olive, D.; Castellano, R.; Guittard, G.; Nunes, J.
10.1101/2021.12.17.473111 — immunology — Posted on 2021-12-19
1341 Genotype and Th2 cells control monocyte to tissue resident macrophage differentiation during nematode infection of the pleural cavity
Finlay, C. M.; Parkinson, J.; Chan, B. H.; Ajendra, J.; Chenery, A.; Morrison, A.; Houlder, E. L.; Baker, S. M.; Dickie, B.; Boon, L.; MacDonald, A. S.; Konkel, J. E.; Rückerl, D.; Allen, J. E.
10.1101/2021.12.17.472661 — immunology — Posted on 2021-12-19
1343 REPTOR/CREBRF encode key regulators of muscle energy metabolism
Saavedra, P.; Dumesic, P. A.; Hu, Y.; Jouandin, P.; Binari, R.; Wilensky, S.; Filine, E.; Rodiger, J.; Wang, H.; Spiegelman, B.; Perrimon, N.
10.1101/2021.12.17.473012 — physiology — Posted on 2021-12-19
1346 Epithelial cells of the intestine acquire cell-intrinsic inflammation signatures during ageing
Funk, M. C.; Gleixner, J. G.; Heigwer, F.; Valentini, E.; Aydin, Z.; Tonin, E.; Hetzer, J.; Heide, D.; Stegle, O.; Heikenwaelder, M.; Boutros, M.
10.1101/2021.12.19.473357 — genomics — Posted on 2021-12-19
1352 Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq
Replogle, J. M.; Saunders, R. A.; Pogson, A. N.; Hussmann, J. A.; Lenail, A.; Guna, A.; Mascibroda, L.; Wagner, E. J.; Adelman, K.; Bonnar, J. L.; Jost, M.; Norman, T. M.; Weissman, J. S.
10.1101/2021.12.16.473013 — genomics — Posted on 2021-12-19
1354 Combining δ13C and δ15N from bone and dentine in marine mammal palaeoecological research: insights from toothed whales
Rey-Iglesia, A.; Wilson, T.; Routledge, J.; Skovrind, M.; Garde, E.; Heide-Jorgensen, M. P.; Szpak, P.; Lorenzen, E. D.
10.1101/2021.12.13.472362 — ecology — Posted on 2021-12-19
1355 NUCLEAR RETENTION OF LEPTIN/UPD2 REGULATES ORGANISMAL RESILIENCE TO NUTRIENT EXTREMES
Poling, M. E.; Sullivan, C. E.; Madan, A.; Kelly, K. P.; Brent, A. E.; Dubrulle, J.; Raghavan, P.; Rajan, A.
10.1101/2021.01.29.428913 — molecular biology — Posted on 2021-12-19
1360 Chromosome remodelling by SMC/Condensin in B. subtilis is regulated by Soj/ParA during growth and sporulation
Roberts, D. M.; Anchimiuk, A.; Kloosterman, T. G.; Murray, H.; Wu, L. J.; Gruber, S.; Errington, J.
10.1101/2021.12.18.473321 — microbiology — Posted on 2021-12-19
1361 Advances in Spiral fMRI: A High-resolution Study with Single-shot Acquisition
Kasper, L.; Engel, M.; Heinzle, J.; Mueller-Schrader, M.; Graedel, N. N.; Reber, J.; Schmid, T.; Barmet, C.; Wilm, B. J.; Stephan, K. E.; Pruessmann, K. P.
10.1101/842179 — neuroscience — Posted on 2021-12-19
1363 Transcriptomic profiling of myeloid cells in Alzheimer's Disease brain illustrates heterogeneity of microglia endolysosomal subtypes
Prater, K. E.; Green, K. J.; Sun, W.; Smith, C.; Chiou, K. L.; Heath, L. M.; Rose, S.; Keene, C. D.; Kwon, R. Y.; Snyder-Mackler, N.; Blue, E.; Young, J. E.; Shojaie, A.; Logsdon, B.; Garden, G. A.; Jayadev, S.
10.1101/2021.10.25.465802 — neuroscience — Posted on 2021-12-19
1364 Role of protein degradation in growth laws
Calabrese, L.; Grilli, J.; Osella, M.; Kempes, C. P.; Cosentino Lagomarsino, M.; Ciandrini, L.
10.1101/2021.03.25.436692 — systems biology — Posted on 2021-12-19
1367 Strategies of tolerance reflected in two North American maple genomes
McEvoy, S. L.; Sezen, U. U.; Trouern-Trend, A.; McMahon, S. M.; Schaberg, P. G.; Yang, J.; Wegrzyn, J. L.; Swenson, N. G.
10.1101/2021.07.19.452996 — genomics — Posted on 2021-12-19
1370 The cell growth cycle in budding yeast: testing hypotheses.
Machne, R.; Bernhart, S. H.; Axmann, I. M.; Stadler, P. F.; Murray, D. B.
10.1101/2021.05.26.444658 — cell biology — Posted on 2021-12-19
1372 Explaining heterogeneity in medial entorhinal cortex with task-driven neural networks
Nayebi, A.; Attinger, A.; Campbell, M. G.; Hardcastle, K.; Low, I. I. C.; Mallory, C. S.; Mel, G. C.; Sorscher, B.; Williams, A. H.; Ganguli, S.; Giocomo, L. M.; Yamins, D. L. K.
10.1101/2021.10.30.466617 — neuroscience — Posted on 2021-12-19
1373 A Scalable and Modular Automated Pipeline for Stitching of Large Electron Microscopy Datasets
Mahalingam, G.; Torres, R.; Kapner, D.; Trautman, E. T.; Fliss, T.; Seshamani, S.; Perlman, E.; Young, R.; Kinn, S.; Buchanan, J.; Takeno, M.; Yin, W.; Bumbarger, D. J.; Gwinn, R. P.; Nyhus, J.; Lein, E.; Smith, S. J.; Reid, C.; Khairy, K.; Saalfeld, S.; Collman, F.; Macarico da Costa, N.
10.1101/2021.11.24.469932 — neuroscience — Posted on 2021-12-19
1374 Chronic Staphylococcus aureus infection is cured by theory-driven therapy
Papaxenopoulou, L. A.; Zao, G.; Khailaie, S.; Katsoulis-Dimitriou, K.; Schmitz, I.; Medina, E.; Hatzikirou, H.; Meyer-Hermann, M.
10.1101/2020.01.17.910786 — systems biology — Posted on 2021-12-19
1376 Positive Selection and Heat-Response Transcriptomes Reveal Adaptive Features of the Arabidopsis Desert Relative, Anastatica hierochuntica
Eshel, G.; Duppen, N.; Wang, G.; Oh, D.-H.; Kazachkova, Y.; Herzyk, P.; Amtmann, A.; Gordon, M.; Chalifa-Caspi, V.; Oscar, M. A.; Bar-David, S.; Marshall-Colon, A.; Dassanayake, M.; Barak, S.
10.1101/2021.05.23.445339 — plant biology — Posted on 2021-12-19
1377 Functional control of a 0.5 MDa TET aminopeptidase by a flexible loop revealed by MAS NMR
Gauto, D. F.; Macek, P.; Malinverni, D.; Fraga, H.; Paloni, M.; Sucec, I.; Hessel, A.; Bustamante, J. P.; Barducci, A.; Schanda, P.
10.1101/2021.06.29.450317 — biophysics — Posted on 2021-12-19
1380 Leukocyte cytokine responses in adult patients with mitochondrial DNA defects
Karan, K. R.; Trumpff, C.; Cross, M.; Englestad, K. M.; Marsland, A. L.; McGuire, P.; Hirano, M.; Picard, M.
10.1101/2021.12.13.472449 — immunology — Posted on 2021-12-19
1381 Speech-driven Facial Animations Improve Speech-in-Noise Comprehension of Humans
Varano, E.; Vougioukas, K.; Ma, P.; Petridis, S.; Pantic, M.; Reichenbach, T.
10.1101/2021.12.18.471222 — neuroscience — Posted on 2021-12-19
1383 Nanoscale patterning of in vitro neuronal circuits
Mateus, J. C.; Weaver, S.; van Swaay, D.; Renz, A.; Hengsteler, J.; Aguiar, P.; Vörös, J.
10.1101/2021.12.16.472887 — neuroscience — Posted on 2021-12-19
1387 Integration of public DNA methylation and expression networks via eQTMs improves prediction of functional gene-gene associations
Li, S.; Qi, C.; Deelen, P.; Boulogne, F.; de Klein, N.; Koppelman, G. H.; van der Velde, K. J.; Franke, L.; Swertz, M. A.; Westra, H.-J.
10.1101/2021.12.17.473125 — bioinformatics — Posted on 2021-12-18
1393 Functional organization of social perception in the human brain
Santavirta, S.; Karjalainen, T.; Nazari-Farsani, S.; Hudson, M.; Putkinen, V.; Seppala, K.; Sun, L.; Glerean, E.; Hirvonen, J.; Karlsson, H. K.; Nummenmaa, L.
10.1101/2021.12.17.473175 — neuroscience — Posted on 2021-12-18
1394 Music-selective cortex is sensitive to structure in both pitch and time
Boebinger, D. L.; Norman-Haignere, S. V.; McDermott, J. H.; Kanwisher, N. G.
10.1101/2021.12.17.473232 — neuroscience — Posted on 2021-12-19
1395 Structural basis for the assembly and electron transport mechanisms of the dimeric photosynthetic RC-LH1 supercomplex
Cao, P.; Bracun, L.; Yamagata, A.; Christianson, B.; Negami, T.; Zou, B.; Terada, T.; Canniffe, D. P.; Shirouzu, M.; Li, M.; Liu, L.-N.
10.1101/2021.12.17.473239 — biochemistry — Posted on 2021-12-18
1399 Translational readthrough as a potential therapeutic for AIPL1-associated Leber Congenital Amaurosis in a patient-derived iPSC-retinal organoid model
Leung, A.; Sacristan-Reviriego, A.; Perdigao, P.; Sai, H.; Georgiou, M.; Kalitzeos, A.; Carr, A.-J. F.; Coffey, P. J.; Michaelides, M.; Bainbridge, J.; Cheetham, M. E.; van der Spuy, J.
10.1101/2021.12.17.473147 — cell biology — Posted on 2021-12-18
1401 Synuclein alpha accumulation mediates podocyte injury in Fabry nephropathy
Abed, A.; Braun, F.; Sellung, D.; Woidy, M.; Eikrem, O. S.; Wanner, N.; von Cossel, K. M.; Muschol, N.; Gersting, S. W.; Muntau, A. C.; Kretz, O.; Najafian, B.; Tondel, C.; Mauer, M.; Bork, T.; Grahammer, F.; Liang, W.; Roemer, W.; Eierhoff, T.; Marti, H.-P.; Puelles, V. G.; Schell, C.; Huber, T. B.
10.1101/2021.12.17.473164 — molecular biology — Posted on 2021-12-18
1402 Comprehensive transcriptional profiling and mouse phenotyping reveals dispensable role for adipose tissue selective long noncoding RNA Gm15551
Engelhard, C. A.; Huang, C.; Khani, S.; Kasparek, P.; Prochazka, J.; Rozman, J.; Reguera, D. P.; Sedlacek, R.; Kornfeld, J.-W.
10.1101/2021.12.17.473160 — molecular biology — Posted on 2021-12-18
1408 Cryo-EM structure of the human CST·Polα/Primase complex in a recruitment state
Cai, S. W.; Zinder, J. C.; Svetlov, V.; Bush, M.; Nudler, E.; Walz, T.; de Lange, T.
10.1101/2021.12.17.473235 — biochemistry — Posted on 2021-12-18
1409 Tissue- and ethnicity-independent hypervariable DNA methylation states show evidence of establishment in the early human embryo
Derakhshan, M.; Kessler, N. J.; Ishida, M.; Demetriou, C.; Brucato, N.; Moore, G. E.; Fall, C. H. D.; Chandak, G. R.; Ricaut, F.-X.; Prentice, A. M.; Hellenthal, G.; Silver, M. J.
10.1101/2021.12.17.473110 — genomics — Posted on 2021-12-18
1410 Single cell mRNA signals reveal a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia
Khabirova, E.; Jardine, L.; Coorens, T.; Webb, S.; Treger, T.; Englebert, J.; Porter, T.; Prigmore, E.; Collord, G.; Piapi, A.; Teichmann, S.; Inglott, S.; Williams, O.; Heidenreich, O.; Young, M. D.; Straathof, K.; Bomken, S.; Bartram, J.; Haniffa, M.; Behjati, S.
10.1101/2021.12.17.473141 — genomics — Posted on 2021-12-18
1411 Adaptive tail-length evolution in deer mice is associated with differential Hoxd13 expression in early development
Kingsley, E. P.; Hager, E. R.; Lassance, J. M.; Turner, K. M.; Harringmeyer, O. S.; Kirby, C.; Neugeboren, B. I.; Hoekstra, H. E.
10.1101/2021.12.18.473263 — genetics — Posted on 2021-12-18
1412 RNA viral communities are structured by host plant phylogeny in oak and conifer leaves
ter Horst, A. M.; Fudyma, J. D.; Bak, A.; Hwang, M. S.; Santos-Medellin, C.; Stevens, K. A.; Rizzo, D. M.; Al Rwahnih, M.; Emerson, J. B.
10.1101/2021.12.17.473209 — ecology — Posted on 2021-12-18
1415 Physico-chemical principles of HDL-small RNA binding interactions.
Michell, D. L.; Allen, R. M.; Cavnar, A. B.; Contreras, D. M.; Yu, M.; Semler, E. M.; Ramirez, M. A.; Zhu, W.; May-Zhang, L.; Raby, C. A.; Castleberry, M.; Ifram, A. M.; Carr, J. J.; Terry, J. G.; Scwendeman, A.; Davies, S. S.; Sheng, Q.; Linton, M. F.; Vickers, K. C.
10.1101/2021.12.17.473011 — molecular biology — Posted on 2021-12-18
1416 Escherichia coli BarA-UvrY regulates the pks island and kills Staphylococci via the genotoxin colibactin
Wong, J. J.; Chong, K. K. L.; Ho, F. K.; Ho, C. M. B.; Neelakandan, R.; Choo, P. Y.; Keogh, D.; Chen, J.; Liu, C. F.; Kline, K. A.
10.1101/2021.12.17.473262 — microbiology — Posted on 2021-12-18
1418 A tale of two plasmids: contributions of plasmid associated phenotypes to epidemiological success among Shigella
De Silva, P. M.; Stenhouse, G. E.; Blackwell, G. E.; Bengtsson, R.; Jenkins, C.; Hall, J. P. J.; Baker, K. S.
10.1101/2021.12.17.473221 — microbiology — Posted on 2021-12-18
1419 Prior exposure to microcystin alters host gut resistome and is associated with dysregulated immune homeostasis in translatable mouse models
Saha, P.; Bose, D.; Stebliankin, V.; Cickovski, T.; Seth, R. K.; Porter, D. E.; Brooks, B. W.; Mathee, K.; Narasimhan, G.; Colwell, R. R.; Scott, G. I.; Chatterjee, S.
10.1101/2021.12.17.472989 — microbiology — Posted on 2021-12-18
1423 CD4 T cells are rapidly depleted from tuberculosis granulomas following acute SIV co-infection
Foreman, T. W.; Nelson, C. E.; Kauffman, K. D.; Lora, N. E.; Vinhaes, C. L.; Dorosky, D. E.; Sakai, S. W.; Gomez, F.; Fleegle, J. D.; Parham, M.; Perera, S. R.; Lindestam Arlehamn, C. S.; Sette, A.; Tuberculosis Imaging Program, ; Brenchley, J. M.; Queiroz, A.; Andrade, B. B.; Kabat, J.; Via, L. E.; Barber, D. L.
10.1101/2021.12.17.473203 — immunology — Posted on 2021-12-18
1424 Overlapping stimulons arising in response to divergent stresses in Escherichia coli
Wang, H.; McElfresh, G.; Wijesuriya, N.; Podgorny, A.; Hecht, A. D.; Ray, J. C. J.
10.1101/2021.12.17.473201 — systems biology — Posted on 2021-12-18
1425 Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation
Kim, T.-E.; Tsuboyama, K.; Houliston, S.; Martell, C. M.; Phoumyvong, C. M.; Haddox, H. K.; Arrowsmith, C. H.; Rocklin, G. J.
10.1101/2021.12.17.472837 — synthetic biology — Posted on 2021-12-18
1426 vRhyme enables binning of viral genomes from metagenomes
Kieft, K.; Adams, A.; Salamzade, R.; Kalan, L.; Anantharaman, K.
10.1101/2021.12.16.473018 — bioinformatics — Posted on 2021-12-18
1430 Visualizing translation dynamics at atomic detail inside a bacterial cell
Xue, L.; Lenz, S.; Zimmermann-Kogadeeva, M.; Tegunov, D.; Cramer, P.; Bork, P.; Rappsilber, J.; Mahamid, J.
10.1101/2021.12.18.473270 — biochemistry — Posted on 2021-12-18
1432 Non-toxigenic Vibrio cholerae challenge strains for evaluating vaccine efficacy and inferring mechanisms of protection
Fakoya, B.; Hullahalli, K.; Rubin, D. H. F.; Leitner, D. R.; Chilengi, R.; Sack, D.; Waldor, M. K.
10.1101/2021.12.17.473008 — microbiology — Posted on 2021-12-18
1433 A third vaccination with a single T cell epitope protects against SARS-CoV-2 infection in the absence of neutralizing antibodies
Pardieck, I. N.; van der Gracht, E. T. I.; Veerkamp, D. M. B.; Behr, F. M.; van Duikeren, S.; Beyrend, G.; Rip, J.; Nadafi, R.; van der Sluis, T. C.; Beyranvand Nejad, E.; Mulling, N.; Brasem, D. J.; Camps, M. G. M.; Myeni, S. K.; Bredenbeek, P. J.; Kikkert, M.; Kim, Y.; Cicin-Sain, L.; Abdelaal, T.; van Gisbergen, K. P. J. M.; Franken, K. L. M. C.; Drijfhout, J. W.; Melief, C. J. M.; Zondag, G. C. M.; Ossendorp, F.; Arens, R.
10.1101/2021.12.15.472838 — immunology — Posted on 2021-12-18
1434 Synaptosome microRNAs regulate synapse functions in Alzheimer's disease
Kumar, S.; Orlov, E.; Gowda, P.; Bose, C.; Orlov, E.; Gowda, P.; Reddy, P. H.
10.1101/2021.12.15.472852 — neuroscience — Posted on 2021-12-18
1437 The first Miocene fossils from coastal woodlands in the southern East African Rift
Bobe, R.; Aldeias, V.; Alemseged, Z.; Archer, W.; Aumaitre, G.; Bamford, M. K.; Biro, D.; Bourles, D. L.; Braun, D. R.; Capelli, C.; d'Oliveira Coelho, J.; Habermann, J. M.; Head, J. J.; Kupczik, K.; Lebatard, A.-E.; Luedecke, T.; Macoa, A.; Martinez, F. I.; Mathe, J.; Meira Paulo, L.; Mendes, C.; Pinto, M.; Puschel, T. A.; Tata Regala, F.; Sier, M.; Ferreira da Silva, M. J.; Stalmans, M.; Carvalho, S.
10.1101/2021.12.16.472914 — paleontology — Posted on 2021-12-18
1438 Primordial capsid and spooled ssDNA genome structures penetrate ancestral events of eukaryotic viruses
Munke, A.; Kimura, K.; Tomaru, Y.; Wang, H.; Yoshida, K.; Mito, S.; Hongo, Y.; Okamoto, K.
10.1101/2021.03.14.435335 — biophysics — Posted on 2021-12-18
1439 High Throughput Intact Protein Analysis Using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry
Pu, F.; Ugrin, S. A.; Radosevich, A. J.; Chang-Yen, D.; Sawicki, J. W.; Talaty, N. N.; Elsen, N. L.; Williams, J. D.
10.1101/2021.11.08.467755 — biochemistry — Posted on 2021-12-18
1441 Fat Body Phospholipid State Dictates Hunger Driven Feeding Behavior
Kelly, K. P.; Alassaf, M.; Sullivan, C. E.; Brent, A. E.; Goldberg, Z. H.; Poling, M. E.; Dubrulle, J.; Rajan, A.
10.1101/2021.12.16.472854 — genetics — Posted on 2021-12-18
1442 Trends in Pacific Canadian groundfish stock status
Anderson, S. C.; Connors, B. M.; English, P. A.; Forrest, R. E.; Haigh, R.; Holt, K. R.
10.1101/2021.12.13.472502 — ecology — Posted on 2021-12-18
1444 Deep Bayesian networks for uncertainty estimation and adversarial resistance of white matter hyperintensity segmentation
Mojiri Forooshani, P.; Biparva, M.; Ntiri, E. E.; Ramirez, J.; Boone, L.; Holmes, M. F.; Adamo, S.; Gao, F.; Ozzoude, M.; Scott, C. J. M.; Dowlatshahi, D.; Lawrence-Dewar, J. M.; Kwan, D.; Lang, A. E.; Marcotte, K.; Leonard, c.; Rochon, E.; Heyn, C.; Bartha, R.; Strother, S.; Tardif, J.-C.; Symons, S.; Masellis, M.; Swartz, R. H.; Moody, A.; Black, S. E.; Goubran, M.
10.1101/2021.08.18.456666 — neuroscience — Posted on 2021-12-18
1448 Fluorescence Activation Mechanism and Imaging of Drug Permeation with New Sensors for Smoking-Cessation Ligands
Nichols, A. L.; Blumenfeld, Z.; Fan, C.; Luebbert, L.; Blom, A. E. M.; Cohen, B. N.; Marvin, J. S.; Borden, P. M.; Kim, C. H.; Muthusamy, A. K.; Shivange, A. V.; Knox, H. J.; Campello, H. R.; Wang, J. H.; Dougherty, D. A.; Looger, L.; Gallagher, T.; Rees, D. C.; Lester, H. A.
10.1101/2021.10.04.463082 — pharmacology and toxicology — Posted on 2021-12-18
1449 Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme
Jacquemin, G.; Wurmser, A.; Huyghe, M.; Sun, W.; Homayed, Z.; Merle, C.; Qasrawi, F.; Perkins, M.; Richon, S.; Dingli, F.; Arras, G.; Loew, D.; Vignjevic, D.; Pannequin, J.; Fre, S.
10.1101/2020.12.16.423051 — cancer biology — Posted on 2021-12-18
1450 The Presence of the Temporal Horn Exacerbates the Vulnerability of Hippocampus during Head Impacts
Zhou, Z.; Li, X.; Domel, A.; Dennis, E.; Georgiadis, M.; Liu, Y.; Raymond, S.; Grant, G.; Kleiven, S.; Camarillo, D.; Zeineh, M.
10.1101/2021.12.07.471634 — bioengineering — Posted on 2021-12-18
1454 Fear in the mind's eye: Mental imagery can generate and regulate acquired differential fear conditioned reactivity
Greening, S. G.; Lee, T.-H.; Burleigh, L.; Gregoire, L.; Robinson, T.; Jiang, X.; Mather, M.; Kaplan, J.
10.1101/2021.02.04.429795 — neuroscience — Posted on 2021-12-18
1455 Identification of phenotype-specific networks from paired gene expression-cell shape imaging data
Barker, C. G.; Petsalaki, E.; Giudice, G.; Sero, J.; Ekpenyong, E. N.; Bakal, C.; Petsalaki, E.
10.1101/2021.02.11.430597 — systems biology — Posted on 2021-12-18
1456 Chemical, molecular, and single cell analysis reveal chondroitin sulfate proteoglycan aberrancy in fibrolamellar carcinoma
Francisco, A.; Li, J.; Farghli, A.; Kanke, M.; Shui, B.; Soloway, P.; Wang, Z.; Reid, L.; Liu, J.; Sethupathy, P.
10.1101/2021.12.07.471610 — cancer biology — Posted on 2021-12-18
1457 How clustered protocadherin binding specificity is tuned for neuronal self/non-self-recognition
Goodman, K. M.; Katsamba, P. S.; Rubinstein, R.; Ahlsen, G.; Bahna, F.; Mannepalli, S.; Dan, H.; Sampogna, R.; Shapiro, L.; Honig, B.
10.1101/2021.07.22.453400 — biophysics — Posted on 2021-12-18
1458 Emerging Accessibility Patterns in Long Telomeric Overhangs
Shiekh, S.; Mustafa, G.; Hoque, M. E.; Yokie, E.; Portman, J. J.; Balci, H.
10.1101/2021.11.24.469879 — biophysics — Posted on 2021-12-18
1461 A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell wall acetylation
Özcam, M.; Oh, J.-H.; Tocmo, R.; Acharya, D.; Zhang, S.; Astmann, T.; Heggen, M.; Ruiz-Ramirez, S.; Li, F.; Cheng, C. C.; Vivas, E.; Rey, F. E.; Claesen, J.; Bugni, T.; Walter, J.; van Pijkeren, J. P.
10.1101/2021.06.11.448121 — microbiology — Posted on 2021-12-18
1462 Nanoscopic dopamine transporter distribution and conformation are inversely regulated by excitatory drive and D2-autoreceptor activity
Lycas, M. D.; Ejdrup, A. L.; Sorensen, A. T.; Haahr, N. O.; Jorgensen, S. H.; Guthrie, D. A.; Stoier, J. F.; Werner, C.; Newman, A. H.; Sauer, M.; Herborg, F. H.; Gether, U.
10.1101/2021.03.09.434538 — neuroscience — Posted on 2021-12-18
1466 Kismet/CHD7/CHD8 affects gut biomechanics, the gut microbiome, and gut-brain axis in Drosophila melanogaster
Niosi, A.; Vo, N. H.; Sundar, P.; Welch, C.; Penn, A.; Yuldasheva, Y.; Alfareh, A.; Rausch, K.; Rukhsar, T.; Cavanaugh, J.; Yadav, P.; Peterson, S.; Brown, R.; Hu, A.; Ardon-Castro, A.; Nguyen, D.; Crawford, R.; Jensen, M. H.; Morris, E. J.; Lee, W.; Mulligan, K.
10.1101/2021.12.17.473216 — developmental biology — Posted on 2021-12-17
1468 Passive epidemiological surveillance in wildlife in Costa Rica identifies pathogens of zoonotic and conservation importance
Alfaro-Alarcon, A.; Aguilar, F.; Solorzono, T.; Baldi, M.; Barquero-Calvo, E.; Jimenez-Rocha, A.; Jimenez, C.; Piche-Ovares, M.; Dolz, G.; Leon, B.; Corrales-Aguilar, E.; Santoro, M.
10.1101/2021.12.17.473220 — pathology — Posted on 2021-12-17
1470 Use of standard U-bottom and V-bottom well plates to generate neuroepithelial embryoid bodies
Choy Buentello, D.; Koch, L. S.; Trujillo-de Santiago, G.; Alvarez, M. M.; Broersen, K.
10.1101/2021.12.17.473219 — developmental biology — Posted on 2021-12-17
1471 Striking Antibody Evasion Manifested by the Omicron Variant of SARS-CoV-2
Liu, L.; Iketani, S.; Guo, Y.; Chan, J. F.-W.; Wang, M.; Liu, L.; Luo, Y.; Chu, H.; Huang, Y.; Nair, M. S.; Yu, J.; Chik, K. K.-H.; Yuen, T. T.-T.; Yoon, C.; To, K. K.-W.; Chen, H.; Yin, M. T.; Sobieszczyk, M. E.; Huang, Y.; Wang, H. H.; Sheng, Z.; Yuen, K.-Y.; Ho, D. D.
10.1101/2021.12.14.472719 — microbiology — Posted on 2021-12-17
1472 Variation in the transcriptome response and detoxification gene diversity drives pesticide tolerance in fishes
Lawrence, M. J.; Grayson, P.; Jeffrey, J. D.; Docker, M. F.; Garroway, C. J.; Wilson, J. M.; Manzon, R.; Wilkie, M. P.; Jeffries, K.
10.1101/2021.12.16.473024 — genomics — Posted on 2021-12-17
1473 Characterizing the genetic basis of trait evolution in the Mexican cavefish
Oliva, C.; Hinz, N. K.; Robinson, W.; Barrett Thompson, A. M.; Booth, J.; Crisostomo, L. M.; Zanineli, S.; Tanner, M.; Lloyd, E.; O'Gorman, M. A.; McDole, B.; Paz, A.; Kozol, R.; Brown, E. B.; Kowalko, J. E.; Fily, Y.; Duboue, E. R.; Keene, A. C.
10.1101/2021.12.16.472318 — evolutionary biology — Posted on 2021-12-17
1476 Dynamic structural cell responses in the thymus to acute injury, regeneration, and age
Jahn, L. L.; Kousa, A. I.; Sikkema, L.; Flores, A. E.; Argyropoulos, K. V.; Tsai, J.; Lazrak, A.; Nichols, K.; Lee, N.; Malard, F.; Andrlova, H.; Gomes, A. L.; Velardi, E.; Youssef, S.; da Silva, M. B.; Docampo, M.; Sharma, R.; Mazoutis, L.; Setty, M.; Pe'er, D.; Manley, N. R.; Dudakov, J. A.; van den Brink, M. R.
10.1101/2021.12.16.472014 — immunology — Posted on 2021-12-17
1477 Loss of Depalmitoylation Exaggerates Synaptic Upscaling and Leads to Neuroinflammation in a Lysosomal Storage Disease
Koster, K. P.; Flores-Barrera, E.; Artur de la Villarmois, E.; Nguyen, T. T. A.; Niqula, A.; Noriega-Gonzalez, L. Y.; Fyke, Z.; Caballero, A.; Cologna, S. M.; Tseng, K. Y.; Yoshii, A.
10.1101/2021.12.16.473002 — neuroscience — Posted on 2021-12-17
1480 OPEN leaf: an open-source cloud-based phenotyping system for tracking dynamic changes at leaf-specific resolution in Arabidopsis
Swartz, L. G. A.; Liu, S.; Dahlquist, D.; Walter, E. S.; Kramer, S.; McInturf, S.; Bucksch, A.; Mendoza-Cozatl, D.
10.1101/2021.12.17.472861 — plant biology — Posted on 2021-12-17
1481 Towards a global perspective for Salvia L: Phylogeny, diversification, and floral evolution
Moein, F.; Jamzad, Z.; Rahiminejad, M.; Landis, J. B.; Mirtadzadini, M.; Soltis, D. E.; Soltis, P. S.
10.1101/2021.12.16.473009 — plant biology — Posted on 2021-12-17
1482 Auxin-driven ecophysiological diversification of leaves in domesticated tomato
dos Reis Moreira, J.; Rosa, B. L.; Lira, B. S.; Lima, J. E.; Souza, L. N.; Otoni, W. C.; Figueira, A.; Freschi, L.; Sakamoto, T.; Peres, L.; Rossi, M.; Zsogon, A.
10.1101/2021.12.16.473023 — plant biology — Posted on 2021-12-17
1484 Effects of ozone on sickness and depressive-like behavioral and biochemical phenotypes and their relations to serum amyloid A and kynurenine in blood
Baumann, K. K.; Liang, W.-S. S.; Quaranta, D. V.; Wilson, M. L.; Asrat, H. S.; Thysell, J. A.; Sarchi, A. V.; Banks, W. A.; Erickson, M. A.
10.1101/2021.12.16.472859 — physiology — Posted on 2021-12-17
1485 Can Chemical Exchange Saturation Transfer (CEST MRI) be used as biomarker of disease progression in Prion Disease?
Demetriou, E.; Tachrount, M.; Ellis, M.; Linehan, J.; Brandner, S.; Collinge, J.; Mead, S. H.; Shmueli, K.; Farrow, M.; Golay, X.
10.1101/2021.12.16.473014 — biophysics — Posted on 2021-12-17
1489 Structure of EPCR in a non-canonical conformation
Lopez-Sagaseta, J.; Erausquin Arrondo, E.; Rodriguez Fernandez, A.
10.1101/2021.12.16.472967 — biochemistry — Posted on 2021-12-17
1490 The aphid BCR4 structure and activity uncover a new defensin peptide superfamily
Loth, K.; Parisot, N.; Paquet, F.; Sivignon, C.; Rahioui, I.; Lopes, M. R.; Gaget, K.; Duport, G.; Delmas, A. F.; Aucagne, V.; Heddi, A.; Calevro, F.; da Silva, P.
10.1101/2021.12.17.472939 — biochemistry — Posted on 2021-12-17
1491 Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq
Replogle, J. M.; Saunders, R. A.; Pogson, A. N.; Hussmann, J. A.; Lenail, A.; Guna, A.; Mascibroda, L.; Wagner, E. J.; Adelman, K.; Bonnar, J. L.; Jost, M.; Norman, T. M.; Weissman, J. S.
10.1101/2021.12.16.473013 — genomics — Posted on 2021-12-17
1493 A genome-edited β-cell model of Prader-Willi syndrome reveals chronic deficits in endoplasmic reticulum chaperones and insulin secretion
Koppes, E. A.; Johnson, M. A.; Moresco, J. J.; Luppi, P.; Lewis, D. W.; Stolz, D. B.; Diedrich, J. K.; Yates, J. R.; Wek, R. C.; Watkins, S. C.; Gollin, S. M.; Park, H. J.; Drain, P.; Nicholls, R. D.
10.1101/2021.12.16.473032 — genetics — Posted on 2021-12-17
1497 Global plant-frugivore trait matching is shaped by climate and biogeographic history
McFadden, I. R.; Fritz, S. A.; Zimmermann, N. E.; Pellissier, L.; Kissling, W. D.; Tobias, J. A.; Schleuning, M.; Graham, C. H.
10.1101/2021.12.17.473099 — ecology — Posted on 2021-12-17
1498 Molecular mechanisms governing circulating immune cell heterogeneity across different species revealed by single cell sequencing
Li, Z.; Sun, c.; Wang, F.; Wang, X.; Zhu, J.; Luo, L.; Ding, X.; Zhang, Y.; Ding, P.; wang, H.; Pu, M.; Li, Y.; wang, S.; Qin, Q.; Wei, Y.; Sun, J.; Wang, X.; Luo, Y.; Chen, D.; Qiu, W.
10.1101/2021.12.17.472326 — cell biology — Posted on 2021-12-17
1499 Sibling rivalry among the ZBTB transcription factor family: homo vs. heterodimers
Piepoli, S.; Nogay, L.; Akkose, U.; Barakat, S.; Taskiran, H.; Tolay, N.; Gezen, M.; Adebali, O.; Atilgan, C.; Erman, B.
10.1101/2021.12.17.472994 — molecular biology — Posted on 2021-12-17
1505 Genomic characteristics of recently recognized Vibrio cholerae El Tor lineages associated with cholera in Bangladesh, 1991-2017
Monir, M. M.; Hossain, T.; Morita, M.; Ohnishi, M.; Johura, F.-t.; Sultana, M.; Monira, S.; Ahmed, T.; Thomson, N.; Watanabe, H.; Huq, A.; Colwell, R. R.; Seed, K. D.; Alam, M.
10.1101/2021.12.16.473094 — genomics — Posted on 2021-12-17
1511 Neural signature of everyday function in older adults at-risk of cognitive impairment
De Sanctis, P.; Wagner, J.; Molholm, S.; Foxe, J. J.; Blumen, H.; Horsthuis, D.
10.1101/2021.12.16.472826 — neuroscience — Posted on 2021-12-17
1514 Multi-omics subtyping of hepatocellular carcinoma patients using a Bayesian network mixture model
Suter, P.; Dazert, E.; Kuipers, J.; Ng, C. K. Y.; Boldanova, T.; Hall, M. N.; Heim, M. H.; Beerenwinkel, N.
10.1101/2021.12.16.473083 — systems biology — Posted on 2021-12-17
1516 LY6S, a New Interferon-Inducible Human Member of the Ly6a-Subfamily Expressed by Spleen Cells and Associated with Inflammation and Viral Resistance
Shmerling, M.; Chalik, M.; Smorodinsky, N. I.; Meeker, A.; Roy, S.; Sagi-Assif, O.; Meshel, T.; Danilevsky, A.; Shomron, N.; Levinger, S.; Nishry, B.; Baruchi, D.; Shargorodsky, A.; Ziv, R.; Sarusi-Portuguez, A.; Lahav, M.; Ehrlich, M.; Braschi, B.; Bruford, E.; Witz, I. P.; Wreschner, D. H.
10.1101/2021.12.16.472998 — genomics — Posted on 2021-12-17
1519 LTBP1 promotes fibrillin incorporation into the extracellular matrix
Przyklenk, M.; Georgieva, V.; Metzen, F.; Mostert, S.; Kobbe, B.; Sengle, G.; Brachvogel, B.; Mecham, R.; Paulsson, M.; Wagener, R.; Koch, M.; Schiavinato, A.
10.1101/2021.12.16.473056 — cell biology — Posted on 2021-12-17
1520 p166 links membrane and intramitochondrial modules of the trypanosomal tripartite attachment complex
Schimanski, B.; Aeschlimann, S.; Käser, S.; Gomez-Fabra Gala, M.; Vögtle, N.; Schneider, A.
10.1101/2021.12.16.473092 — cell biology — Posted on 2021-12-17
1521 The Trypanosoma cruzi kinetoplast DNA minicircle sequences transfer biomarker of the multidrug treatment of Chagas disease
Teixeira, A. R. L.; Sousa, A. O.; Gomes, C. C.; Sa, A. A.; Nascimento, R. J.; Pires, L. L.; Castro, A. M.; Moreno, F. B.
10.1101/2021.12.16.473091 — molecular biology — Posted on 2021-12-17
1522 A high-throughput neutralization assay for yellow fever serodiagnostics
Rasulova, M.; Vercruysse, T.; Paulissen, J.; Coun, C.; Suin, V.; Heyndrickx, L.; Ma, J.; Geerts, K.; Timmermans, J.; Mishra, N.; Li, L.-H.; Kum, D. B.; Coelmont, L.; Van Gucht, S.; Karimzadeh, H.; Thorn-Seshold, J.; Rothenfusser, S.; Ariën, K. K.; Neyts, J.; Dallmeier, K.; Thibaut, H. J.
10.1101/2021.12.16.472971 — microbiology — Posted on 2021-12-17
1525 Reconstitution of T cell immunity against EBV in the immunocompromised host by adoptive transfer of peptide-stimulated T cells after allogeneic stem cell transplantation
Lammoglia Cobo, M. F.; Ritter, J.; Gary, R.; Seitz, V.; Mautner, J.; Aigner, M.; Völkl, S.; Schaffer, S.; Moi, S.; Seegebarth, A.; Bruns, H.; Rösler, W.; Amann, K.; Büttner-Herold, M.; Hennig, S.; Mackensen, A.; Hummel, M.; Moosmann, A.; Gerbitz, A.
10.1101/2021.12.16.473087 — immunology — Posted on 2021-12-17
1526 Disrupting ATXN1 Nuclear Localization in a Knock-in SCA1 Mouse Model Improves a Spectrum of SCA1-Like Phenotypes and their Brain Region Associated Transcriptomic Profiles
Orr, H. T.; Handler, H. P.; Duvick, L.; Mitchell, J.; Cvetanovic, M.; Reighard, M.; Soles, A.; Rainwater, O.; Serres, S.; Nichols-Meade, T.; Coffin, S. L.; Yoou, Y.; Ruis, B.; Ocallaghan, B.; Henzler, C.; Zoghbi, H. Y.
10.1101/2021.12.16.472987 — neuroscience — Posted on 2021-12-17
1527 Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy
Lövestam, S.; Koh, F. A.; van Knippenberg, B.; Kotecha, A.; Murzin, A. G.; Goedert, M.; Scheres, S.
10.1101/2021.12.16.472950 — neuroscience — Posted on 2021-12-17
1528 Dopamine and GPCR-mediated modulation of DN1 clock neurons gates the circadian timing of sleep
Schlichting, M.; Richhariya, S.; Herndon, N.; Ma, D.; Xin, J.; Lenh, W.; Abruzzi, K.; Rosbash, M.
10.1101/2021.12.16.472997 — neuroscience — Posted on 2021-12-17
1533 Amino acid substitutions in human growth hormone affect coiled-coil content and receptor binding
Rajkovic, A.; Kanchugal, S.; Abdurakhmanov, E.; Howard, R.; Gräslund, A.; Wärmländer, S.; Erwin, J.; Danielson, H. U.; Flores, S. C.
10.1101/2021.12.16.473085 — bioengineering — Posted on 2021-12-17
1534 Resistance to miltefosine results from amplification of the RTA3 floppase or inactivation of flippases in Candida parapsilosis
Bergin, S.; Zhao, F.; Ryan, A. P.; Müller, C. A.; Nieduszynski, C. A.; Zhai, B.; Rolling, T.; Hohl, T. M.; Morio, F.; Scully, J.; Wolfe, K. H.; Butler, G.
10.1101/2021.12.16.473093 — genomics — Posted on 2021-12-17
1537 Tryptophol acetate and tyrosol acetate, metabolites secreted by a probiotic yeast, halt cytokine storm
malka, o.; malishev, r.; bersudsky, m.; rajendran, m.; krishnamohan, m.; shaik, j.; tikhonov, e.; sultan, e.; koren, o.; apte, r.; rosental, b.; voronov, e.; jelinek, r.
10.1101/2021.12.16.472991 — immunology — Posted on 2021-12-17
1538 Population coding and oscillatory subspace synchronization integrate context into actions
Weber, J.; Solbakk, A.-K.; Blenkmann, A.; Llorens, A.; Funderud, I.; Leske, S.; Larsson, P. G.; Ivanovic, J.; Knight, R. T.; Endestad, T.; Helfrich, R.
10.1101/2021.12.17.473118 — neuroscience — Posted on 2021-12-17
1539 Nanoscale patterning of in vitro neuronal circuits
Vörös, J.; Weaver, S.; Mateus, J. C.; Aguiar, P.; van Swaay, D.; Renz, A.; Hengsteler, J.
10.1101/2021.12.16.472887 — neuroscience — Posted on 2021-12-17
1540 Low Frequency Oscillations drive EEG's complexity changes during wakefulness and sleep
Gonzalez, J.; Mateos, D. M.; Cavelli, M.; Mondino, A.; Pascovich, C.; Torterolo, P.; Rubido, N.
10.1101/2021.12.16.472983 — neuroscience — Posted on 2021-12-17
1542 The grape MYB24 mediates the coordination of light-induced terpene and flavonol accumulation in response to berry anthocyanin sunscreen depletion
Zhang, C.; Dai, Z.; Ferrier, T.; Orduna, L.; Santiago, A.; Peris, A.; Wong, D.; Kappel, C.; Savoi, S.; Loyola, R.; Amato, A.; Kozak, B.; Li, M.; Carrasco, D.; Meyer, C.; Espinoza, C.; Hilbert, G.; Figueroa-Balderas, R.; Cantu, D.; Arroyo, R.; Arce-Johnson, P.; Claudel, P.; Duchene, E.; Huang, S.-s. C.; Castellarin, S. D.; Tornielli, G. B.; Barrieu, F.; Matus, J. T.
10.1101/2021.12.16.472692 — plant biology — Posted on 2021-12-17
1544 Genome Assemblies of the Warthog and Kenyan Domestic Pig Provide Insights into Suidae Evolution and Candidate Genes for African Swine Fever Tolerance
Feng, W.; Zhou, L.; Zhao, P.; Du, H.; Diao, C.; Zhang, Y.; Liu, Z.; Jin, W.; Yu, J.; Han, J.; Okoth, E.; Morode, R.; Liu, J.-F.
10.1101/2021.12.17.473133 — genetics — Posted on 2021-12-17
1545 Using ultraconserved elements to reconstruct the termite tree of life
Hellemans, S.; Wang, M.; Hasegawa, N.; Sobotnik, J.; Scheffrahn, R. H.; Bourguignon, T.
10.1101/2021.12.09.472027 — evolutionary biology — Posted on 2021-12-17
1546 `rbioacc`: an R-package to analyse toxicokinetic data
Ratier, A.; Baudrot, V.; Kaag, M.; Siberchicot, A.; Lopes, C.; CHARLES, S.
10.1101/2021.09.08.459421 — ecology — Posted on 2021-12-17
1551 SIMBA: SIngle-cell eMBedding Along with features
Chen, H.; Ryu, J.; Vinyard, M. E.; Lerer, A.; Pinello, L.
10.1101/2021.10.17.464750 — bioinformatics — Posted on 2021-12-17
1552 De Novo Whole Genome Assembly of the Roborovski Dwarf Hamster (Phodopus roborovskii) Genome, an Animal Model for Severe/Critical COVID-19
Andreotti, S.; Altmüller, J.; Quedenau, C.; Borodina, T.; Nouailles, G.; Teixeira Alves, L. G.; Landthaler, M.; Bieniara, M.; Trimpert, J.; Wyler, E.
10.1101/2021.10.02.462569 — genomics — Posted on 2021-12-17
1553 An infectious SARS-CoV-2 B.1.1.529 Omicron virus escapes neutralization by several therapeutic monoclonal antibodies
VanBlargan, L. A.; Errico, J. M.; Halfmann, P.; Zost, S. J.; Crowe, J. E.; Purcell, L. A.; Kawaoka, Y.; Corti, D.; Fremont, D. H.; Diamond, M.
10.1101/2021.12.15.472828 — microbiology — Posted on 2021-12-17
1554 Distinguishing COVID-19 infection and vaccination history by T cell reactivity
Yu, E. D.; Wang, E.; Garrigan, E.; Goodwin, B.; Sutherland, A.; Chang, J.; Galvez, R. I.; Mateus, J.; Rawlings, S. A.; Smith, D. M.; Frazier, A.; Weiskopf, D.; Dan, J. M.; Crotty, S.; Grifoni, A.; Sette, A.; da Silva Antunes, R.
10.1101/2021.12.15.472874 — immunology — Posted on 2021-12-17
1557 A method to estimate the cellular composition of the mouse brain from heterogeneous datasets
Rodarie, D.; Veraszto, C.; Roussel, Y.; Reimann, M.; Keller, D.; Ramaswamy, S.; Markram, H.; Gewaltig, M.-O.
10.1101/2021.11.20.469384 — neuroscience — Posted on 2021-12-17
1559 Fat Body Phospholipid State Dictates Hunger Driven Feeding Behavior
Kelly, K. P.; Alassaf, M.; Sullivan, C. E.; Brent, A. E.; Goldberg, Z. H.; Poling, M. E.; Dubrulle, J.; Rajan, A.
10.1101/2021.12.16.472854 — physiology — Posted on 2021-12-17
1562 Isolation disrupts social interactions and destabilizes brain development in bumblebees
Wang, Z. Y.; McKenzie-Smith, G. C.; Liu, W.; Cho, H. J.; Pereira, T. D.; Dhanerawala, Z.; Shaevitz, J. W.; Kocher, S. D.
10.1101/2021.12.16.472962 — animal behavior and cognition — Posted on 2021-12-17
1563 A practical guide for generating unsupervised, spectrogram-based latent space representations of animal vocalizations
Thomas, M.; Jensen, F.; Averly, B.; Demartsev, V.; Manser, M. B.; Sainburg, T.; Roch, M.; Strandburg-Peshkin, A.
10.1101/2021.12.16.472881 — animal behavior and cognition — Posted on 2021-12-17
1567 A seasonal pulse of ungulate neonates influences space use by carnivores in a multi-predator, multi-prey system
Ruprecht, J.; Forrester, T. D.; Jackson, N. J.; Clark, D. A.; Wisdom, M. J.; Rowland, M. M.; Smith, J. B.; Stewart, K. M.; Levi, T.
10.1101/2021.12.16.472870 — ecology — Posted on 2021-12-17
1568 imageseg: an R package for deep learning-based image segmentation
Niedballa, J.; Axtner, J.; Döbert, T. F.; Tilker, A.; Nguyen, A.; Wong, S. T.; Fiderer, C.; Heurich, M.; Wilting, A.
10.1101/2021.12.16.469125 — ecology — Posted on 2021-12-17
1569 Social evolution of shared biofilm matrix components
Tai, J.-S. B.; Mukherjee, S.; Nero, T.; Olson, R.; Tithof, J.; Nadell, C. D.; Yan, J.
10.1101/2021.12.16.472970 — ecology — Posted on 2021-12-17
1570 4D reconstruction of developmental trajectories using spherical harmonics
Dalmasso, G.; Musy, M.; Niksic, M.; Robert-Moreno, A.; Badia-Careaga, C.; Sanz-Ezquerro, J. J.; Sharpe, J.
10.1101/2021.12.16.472948 — developmental biology — Posted on 2021-12-17
1571 QTQTN motif upstream of the furin-cleavage site plays key role in SARS-CoV-2 infection and pathogenesis.
Vu, M. N.; Lokugamage, K.; Plante, J. A.; Scharton, D.; Johnson, B. A.; Sotcheff, S.; Swetnam, D.; Schindewolf, C.; Alvarado, R. E.; Crocquet-Valdes, P. A.; Debbink, K.; Weaver, S.; Walker, D. H.; Routh, A. L.; Plante, K. S.; Menachery, V. D.
10.1101/2021.12.15.472450 — microbiology — Posted on 2021-12-17
1572 Divergent clonal differentiation trajectories of T cell exhaustion
Daniel, B.; Yost, K. E.; Sandor, K.; Xia, Y.; Qi, Y.; Hiam-Galvez, K. J.; Meier, S. L.; Belk, J.; Giles, J. R.; Wherry, E. J.; Chang, H.; Egawa, T.; Satpathy, A.
10.1101/2021.12.16.472900 — immunology — Posted on 2021-12-17
1573 Ensovibep, a novel trispecific DARPin candidate that protects against SARS-CoV-2 variants
Rothenberger, S.; Hurdiss, D. L.; Walser, M.; Malvezzi, F.; Mayor, J.; Ryter, S.; Moreno, H.; Liechti, N.; Bosshart, A.; Iss, C.; Calabro, V.; Cornelius, A.; Hospodarsch, T.; Neculcea, A.; Looser, T.; Schlegel, A.; Fontaine, S.; Villemagne, D.; Paladino, M.; Kaufmann, Y.; Schaible, D.; Schlegel, I.; Schiegg, D.; Zitt, C.; Sigrist, G.; Straumann, M.; Wolter, J.; Comby, M.; Adler, J. M.; Eschke, K.; Nascimento, M.; Abdelgawad, A.; Gruber, A. D.; Bushe, J.; Kershaw, O.; Lyoo, H.; Wang, C.; Li, W.; Drulyte, I.; Du, W.; Binz, K.; Herrup, R.; Lusvarghi, S.; Neerukonda, S. N.; Vassell, R.; Wang, W.;
10.1101/2021.02.03.429164 — immunology — Posted on 2021-12-17
1576 Categorical working memory codes in human visual cortex
Yan, C.; Christophel, T. B.; Allefeld, C.; Haynes, J.-D.
10.1101/2021.12.16.472288 — neuroscience — Posted on 2021-12-17
1577 Prolonged nicotine exposure reduces aversion to the drug in mice by altering nicotinic transmission in the interpeduncular nucleus.
Mondoloni, S.; Nguyen, C.; Vicq, E.; Jehl, J.; Durand-de Cuttoli, R.; Torquet, N.; Tolu, S.; Pons, S.; Maskos, U.; Marti, F.; Faure, P.; Mourot, A.
10.1101/2021.12.16.472949 — neuroscience — Posted on 2021-12-17
1579 Aberrant Fucosylation of Saliva Glycoprotein Defining Lung Adenocarcinomas Malignancy
Yang, S.; Gao, Z.; Wu, Z.; Han, Y.; Zhang, X.; Hao, P.; Xu, M.; Huang, S.; Li, S.; Xia, J.; Jiang, J.
10.1101/2021.12.16.472888 — systems biology — Posted on 2021-12-17
1581 Changes in blood cell deformability in Chorea-Acanthocytosis and effects of treatment with dasatinib or lithium
Reichel, F.; Kraeter, M.; Peikert, K.; Glass, H.; Rosendahl, P.; Herbig, M.; Prieto, A. R.; Kihm, A.; Kaestner, L.; Hermann, A.; Guck, J.
10.1101/2021.12.16.472921 — biophysics — Posted on 2021-12-17
1583 seGMM: a new tool to infer sex from massively parallel sequencing data
Liu, S.; Zeng, Y.; Chen, M.; Zhang, Q.; Wang, L.; Wang, C.; Lu, Y.; Guo, H.; Bu, F.
10.1101/2021.12.16.472877 — bioinformatics — Posted on 2021-12-17
1589 Interest of phenomic prediction as an alternative to genomic prediction in grapevine
Brault, C.; Lazerges, J.; Doligez, A.; Thomas, M.; Ecarnot, M.; Roumet, P.; Bertrand, Y.; Berger, G.; Pons, T.; Francois, P.; Le Cunff, L.; This, P.; Segura, V.
10.1101/2021.12.16.472608 — genetics — Posted on 2021-12-17
1591 Genomic signatures of desert adaptation at gene-rich regions in zebu cattle from the African drylands
Tijjani, A.; Salim, B.; Barbosa da Silva, M. V.; Eltahir, H. A.; Musa, T. H.; Marshall, K.; Hanotte, O.; Musa, H. H.
10.1101/2021.12.15.472850 — evolutionary biology — Posted on 2021-12-17
1592 Declining population sizes and loss of genetic diversity in commercial fishes: a simple method for a first diagnostic
Petit-Marty, N. P.; Min, L.; Tan, I. Z.; Chung, A.; Terrasa, B.; Guijarro, B.; Ordines, F.; Ramirez-Amaro, S.; Massuti, E.; Schunter, C.
10.1101/2021.12.16.472909 — ecology — Posted on 2021-12-17
1593 Unraveling the roles of Mast4 in amelogenesis via regulating DLX3 and stem cell maintenance of mouse incisors
Lee, D.-J.; Kim, P.; Kim, H.-Y.; Park, J.; Lee, S.-J.; An, H.; Heo, J. S.; Lee, M.-J.; Ohshima, H.; Mizuno, S.; Takahashi, S.; Jung, H.-S.; Kim, S.-J.
10.1101/2021.12.15.472878 — developmental biology — Posted on 2021-12-17
1595 RFX6-mediated dysregulation defines human β cell dysfunction in early type 2 diabetes
Walker, J. T.; Saunders, D. C.; Rai, V.; Dai, C.; Orchard, P.; Hopkirk, A. L.; Reihsmann, C. V.; Tao, Y.; Fan, S.; Shrestha, S.; Varshney, A.; Wright, J. J.; Pettway, Y. D.; Ventresca, C.; Agarwala, S.; Aramandla, R.; Poffenberger, G.; Jenkins, R.; Hart, N. J.; Greiner, D. L.; Shultz, L. D.; Bottino, R.; Human Pancreas Analysis Program, ; Liu, J.; Parker, S. C. J.; Powers, A. C.; Brissova, M.
10.1101/2021.12.16.466282 — cell biology — Posted on 2021-12-17
1596 The effects of locomotion on sensory-evoked haemodynamic responses in the cortex of awake mice
Eyre, B.; Shaw, K.; Sharp, P.; Boorman, L.; Lee, L.; Shabir, O.; Berwick, J.; Howarth, C.
10.1101/2021.12.16.472794 — neuroscience — Posted on 2021-12-17
1597 A brain atlas of synapse protein lifetime across the mouse lifespan.
Bulovaite, E.; Qiu, Z.; Kratschke, M.; Zgraj, A.; Fricker, D.; Tuck, E.; Gokhale, R.; Jami, S.; Merino-Serrais, P.; Husi, E.; O'Dell, T. J.; DeFelipe, J.; Komiyama, N.; Holtmaat, A.; Fransen, E.; Grant, S. G. N.
10.1101/2021.12.16.472938 — neuroscience — Posted on 2021-12-17
1603 isomiRs-specific differential expression is the rule, not the exception: Are we missing hundreds of species in microRNA analysis?
Schmauch, E.; Laitinen, P.; Turunen, T. A.; Vaananen, M.-A.; Malm, T.; Kellis, M.; Kaikkonen, M. U.; Linna-Kuosmanen, S.
10.1101/2021.12.15.472814 — bioinformatics — Posted on 2021-12-17
1605 Precise quantification of behavioral individuality from 80 million decisions across 183,000 flies
de Bivort, B. L.; Buchanan, S. M.; Skutt-Kakaria, K. J.; Gajda, E.; O'Leary, C. J.; Reimers, P.; Akhund-Zade, J.; Senft, R.; Maloney, R.; Ho, S.; Werkhoven, Z.; Smith, M. A.-Y.
10.1101/2021.12.15.472856 — neuroscience — Posted on 2021-12-17
1606 Genetic Sex Validation for Sample Tracking in Clinical Testing
Hu, J.; Korchina, V.; Zouk, H.; Harden, M. V.; Murdock, D.; Alyssa Macbeth, A.; Harrison, S. M.; Lennon, N.; Kovar, C.; Balasubramanian, A.; Zhang, L.; Chandanavelli, G.; Pasham, D.; Rowley, R.; Wiley, K.; Smith, M. E.; Gordon, A.; Jarvik, G. P.; Sleiman, P.; Kelly, M. A.; Bland, S. T.; Murugan, M.; Venner, E.; Boerwinkle, E.; the eMERGE III consortium, ; Prows, C.; Mahanta, L.; Rehm, H. L.; Gibbs, R. A.; Muzny, D. M.
10.1101/2021.12.13.470986 — genomics — Posted on 2021-12-17
1607 Dynamic in situ confinement triggers ligand-free neuropeptide receptor signaling
Tampe, R.; Sanchez, M. F.; Dietz, M. S.; Müller, U.; Weghuber, J.; Gatterdam, K.; Wieneke, R.; Heilemann, M.; Lanzerstorfer, P.
10.1101/2021.12.15.472742 — biophysics — Posted on 2021-12-17
1611 Phosphatidylinositol Acyl Chains Configure Priming and Activation of the NLRP3 Inflammasome
Hamilton, C.; Olona, A.; Leishman, S.; MacDonald-Ramsahai, K.; Cockcroft, S.; Larrouy-Maumus, G.; Anand, P. K.
10.1101/2020.01.14.905075 — immunology — Posted on 2021-12-17
1612 Lactate regulation of activation in CD8+ T cells
Barbieri, L.; Velica, P.; Gameiro, P. A.; Cunha, P. P.; Foskolou, I. P.; Bargiela, D.; Rundqvist, H.; Johnson, R.
10.1101/2021.12.14.472728 — immunology — Posted on 2021-12-17
1613 A reference induced pluripotent stem cell line for large-scale collaborative studies
Pantazis, C. B.; Yang, A.; Lara, E.; McDonough, J. A.; Blauwendraat, C.; Peng, L.; Oguro, H.; Zou, J.; Sebesta, D.; Pratt, G.; Cross, E.; Blockwick, J.; Buxton, P.; Kinner-Bibeau, L.; Medura, C.; Tompkins, C.; Hughes, S.; Santiana, M.; Faghri, F.; Nalls, M. A.; Vitale, D.; Qi, Y. A.; Ramos, D. M.; Anderson, K.; Stadler, J.; Narayan, P.; Papademetriou, J.; Reilly, L.; Nelson, M. P.; Aggarwal, S.; Rosen, L. U.; Kirwan, P.; Pisupati, V.; Coon, S. L.; Scholz, S. W.; Coccia, E.; Sarrafha, L.; Ahfeldt, T.; Funes, S.; Bosco, D. A.; Beccari, M. S.; Cleveland, D. W.; Zanellati, M. C.; Basundra, R.; Des
10.1101/2021.12.15.472643 — neuroscience — Posted on 2021-12-17
1620 High-affinity nanobodies as tools for structural and functional studies on mammalian Arc
Markusson, S.; Hallin, E. I.; Bustad, H. J.; Raasakka, A.; Xu, J.; Muruganandam, G.; Loris, R.; Martinez, A.; Bramham, C.; Kursula, P.
10.1101/2021.12.16.472929 — biochemistry — Posted on 2021-12-17
1621 Direct Imaging and Identification of Proteoforms up to 70 kDa from Human Tissue
Su, P.; McGee, J. P.; Durbin, K. R.; Hollas, M. A. R.; Yang, M.; Neumann, E. K.; Allen, J. L.; Drown, B. S.; Butun, F. A.; Greer, J. B.; Early, B. P.; Fellers, R. T.; Spraggins, J. M.; Laskin, J.; Camarillo, J. M.; Kafader, J. O.; Kelleher, N. L.
10.1101/2021.12.07.471638 — biochemistry — Posted on 2021-12-17
1622 Multiple genes in cis mediate the effects of a single chromatin accessibility variant on aberrant synaptic development and function in human neurons
Zhang, S.; Zhang, H.; Forrest, M.; Zhou, Y.; Bagchi, V. A.; Kozlova, A.; Santos, M. D.; Piguel, N.; Dionisio, L. E.; Sanders, A. R.; Pang, Z. P.; He, X.; Penzes, P.; Duan, J.
10.1101/2021.12.11.472229 — genetics — Posted on 2021-12-17
1623 Gene loss during a transition to multicellularity
Jimenez-Marin, B.; Rakijas, J. B.; Tyagi, A.; Pandey, A.; Hanschen, E. R.; Anderson, J.; Heffel, M. G.; Platt, T. G.; Olson, B. J. S. C.
10.1101/2021.02.16.431445 — evolutionary biology — Posted on 2021-12-17
1626 Anatomic development of the upper airway during the first five years of life: A three-dimensional imaging study
Chuang, Y. J.; Hwang, S. J.; Buhr, K. A.; Miller, C. A.; Avey, G. D.; Story, B. H.; Vorperian, H. K.
10.1101/2021.10.26.465942 — developmental biology — Posted on 2021-12-17
1627 A comprehensive approach for artifact-free sample preparation and assessment of mitochondrial morphology in tissue and cultured cells
Hinton, A.; Katti, P.; Christensen, T. A.; Mungai, M.; Shao, J.; Zhang, L.; Trushin, S.; Alghanem, A.; Jaspersen, A.; Geroux, R. E.; Neikirk, K.; Biete, M.; Garza Lopez, E.; Vue, Z.; Beasley, H.; Marshall, A.; Bleck, C. K. E.; Hicsasmaz, I.; Murray, S. A.; Edmonds, R. A. C.; Dajles, A.; Koo, Y. D.; Bacevac, S.; Salisbury, J. L.; Pereira, R. O.; Glancy, B.; Trushina, E.; Abel, E. D.
10.1101/2021.06.27.450055 — cell biology — Posted on 2021-12-17
1628 Mammary ductal epithelium controls cold-induced adipocyte thermogenesis
Santos, L. C.; Arneson, D.; Alvarsson, A.; Chella Krishnan, K.; Centzone, A.; Patel, S.; Sadeh, S.; Ahn, I. S.; Diamante, G.; Cely, I.; Butte, A. J.; Blanpain, C.; Stanley, S. A.; Lusis, A. J.; Yang, X.; Rajbhandari, P.
10.1101/2020.11.14.378687 — cell biology — Posted on 2021-12-17
1629 Adenine Base Editing in vivo with a Single Adeno-Associated Virus Vector
Zhang, H.; Bamidele, N.; Liu, P.; Ojelabi, O.; Gao, X. D.; Rodriguez, T.; Cheng, H.; Wolfe, S. A.; Xue, W.; Sontheimer, E. J.
10.1101/2021.12.13.472434 — molecular biology — Posted on 2021-12-17
1633 Enhanced nociceptor sprouting in a rabbit model of cerebral palsy
Reedich, E. J.; Genry, L. T.; Singer, M. A.; Cavarsan, C. F.; Mena Avila, E.; Boudreau, D. M.; Brennan, M. C.; Garrett, A. M.; Dowaliby, L.; Detloff, M. R.; Quinlan, K. A.
10.1101/2021.09.28.462176 — neuroscience — Posted on 2021-12-17
1634 Mathematical Relationships between Spinal Motoneuron Properties
Caillet, A. H. D.; Phillips, A. T. M.; Farina, D.; Modenese, L.
10.1101/2021.08.05.455188 — neuroscience — Posted on 2021-12-17
1635 Optimal information loading into working memory in prefrontal cortex
Stroud, J. P.; Watanabe, K.; Suzuki, T.; Stokes, M. G.; Lengyel, M.
10.1101/2021.11.16.468360 — neuroscience — Posted on 2021-12-17
1636 Coordinated multiplexing of information about separate objects in visual cortex
Jun, N. Y.; Ruff, D. A.; Kramer, L. E.; Bowes, B.; Tokdar, S. T.; Cohen, M. R.; Groh, J. M.
10.1101/777912 — neuroscience — Posted on 2021-12-17
1638 EXPRESSION OF A SECRETABLE, CELL-PENETRATING CDKL5 PROTEIN ENHANCES THE EFFICACY OF AAV VECTOR-MEDIATED GENE THERAPY FOR CDKL5 DEFICIENCY DISORDER.
Medici, G.; Tassinari, M.; Galvani, G.; Bastianini, S.; Gennaccaro, L.; Loi, M.; Mottolese, N.; Alvente, S.; Berteotti, C.; Sagona, G.; Lupori, L.; Bagget, H. R.; Zoccoli, G.; Giustetto, M.; Muotri, A. R.; Pizzorusso, T.; Nakai, H.; Trazzi, S.; Ciani, E.
10.1101/2021.07.26.453746 — neuroscience — Posted on 2021-12-17
1640 AutoMicroED: A semi-automated MicroED processing pipeline
Powell, S. M.; Novikova, I. V.; Kim, D. N.; Evans, J. E.
10.1101/2021.12.13.472146 — biophysics — Posted on 2021-12-17
1645 Anisotropic interaction and motion states of locusts in a hopper band
Weinburd, J.; Landsberg, J.; Kravtsova, A.; Lam, S.; Sharma, T.; Simpson, S. J.; Sword, G. A.; Buhl, J.
10.1101/2021.10.29.466390 — animal behavior and cognition — Posted on 2021-12-17
1647 Multiple lines of evidence combine to understand tree species coexistence
McNickle, G. G.; Ritzi, M. V.; Blackstone, K. M. S.; Couture, J. J.; Nelson, T.; Hardiman, B. S.; Montague, M. S.; Jacobs, D. F.
10.1101/2021.07.13.452199 — ecology — Posted on 2021-12-17
1648 EXOSC10/Rrp6 is essential for the eight-cell embryo/morula transition
Petit, F. G.; Jamin, S. P.; Kernanec, P.-Y.; Becker, E.; Halet, G.; Primig, M.
10.1101/2021.10.06.463350 — developmental biology — Posted on 2021-12-17
1649 Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions
Yifrach, E.; Holbrook-Smith, D.; Burgi, J.; Othman, A.; Eisenstein, M.; Van Roermund, C. W. T.; Visser, W.; Tirosh, A.; Bibi, C.; Galor, S.; Weil, U.; Fadel, A.; Peleg, Y.; Waterham, H.; Wanders, R. J.; Wilmanns, M.; Zamboni, N.; Schuldiner, M.; Zalckvar, E.
10.1101/2021.12.08.471723 — cell biology — Posted on 2021-12-17
1650 Quantitative Mapping of Keratin Networks in 3D
Windoffer, R.; Schwarz, N.; Yoon, S.; Piskova, T.; Scholkemper, M.; Stegmaier, J.; Bönsch, A.; Di Russo, J.; Leube, R.
10.1101/2021.12.06.470977 — cell biology — Posted on 2021-12-17
1651 Rhomboid protease RHBDL4 promotes retrotranslocation of aggregation-prone proteins for degradation
Bock, J.; Kuehnle, N.; Knopf, J. D.; Landscheidt, N.; Lee, J.-G.; Ye, Y.; Lemberg, M. K.
10.1101/848754 — cell biology — Posted on 2021-12-17
1653 Intracranial human recordings reveal intensity coding for the pain of others in the insula
Soyman, E.; Bruls, R.; Ioumpa, K.; Müller-Pinzler, L.; Gallo, S.; van Straaten, E. C. W.; Self, M. W.; Peters, J. C.; Possel, J. K.; Onuki, Y.; Baayen, J. C.; Idema, S.; Keysers, C.; Gazzola, V.
10.1101/2021.06.23.449371 — neuroscience — Posted on 2021-12-17
1655 Qualifying a human Liver-Chip for predictive toxicology: Performance assessment and economic implications
Ewart, L.; Apostolou, A.; Briggs, S. A.; Carman, C. V.; Chaff, J. T.; Heng, A. R.; Jadalannagari, S.; Janardhanan, J.; Jang, K.-J.; Joshipura, S. R.; Kadam, M.; Kanellias, M.; Kujala, V. J.; Kulkarni, G.; Le, C. Y.; Lucchesi, C.; Manatakis, D.; Maniar, K. K.; Quinn, M. E.; Ravan, J. S.; Rizos, A. C.; Sauld, J. F. K.; Sliz, J.; Tien-Street, W.; Trinidad, D. R.; Velez, J.; Wendell, M.; Irrechukwu, O.; Mahalingaiah, P. K.; Ingber, D. E.; Levner, D.
10.1101/2021.12.14.472674 — pharmacology and toxicology — Posted on 2021-12-17
1656 Classical Mathematical Models for Prediction of Response to Chemotherapy and Immunotherapy
Ghaffari Laleh, N.; Loeffler, C. M. L.; Grajek, J.; Stankova, K.; Pearson, A. T.; Muti, H. S.; Trautwein, C.; Enderling, H.; Poleszczuk, J.; Kather, J. N.
10.1101/2021.10.23.465549 — cancer biology — Posted on 2021-12-17
1657 Comparative assessment of genes driving cancer and somatic evolution.
Dressler, L.; Bortolomeazzi, M.; Keddar, M. R.; Misetic, H.; Sartini, G.; Acha-Sagredo, A.; Montorsi, L.; Wijewardhane, N.; Repana, D.; Nulsen, J.; Goldman, J.; Pollit, M.; Davis, P.; Strange, A.; Ambrose, K.; Ciccarelli, F. D.
10.1101/2021.08.31.458177 — cancer biology — Posted on 2021-12-17
1664 Protein Posttranslational Signatures Identified in COVID-19 Patient Plasma
Vedula, P.; Tang, H.-Y.; UPenn COVID Processing Unit, ; Speicher, D.; Kashina, A.
10.1101/2021.12.15.472822 — biochemistry — Posted on 2021-12-16
1665 Interferon-gamma mediates skeletal muscle lesions through JAK/STAT pathway activation in inclusion body myositis
Hou, C.; Periou, B.; Gervais, M.; Berthier, J.; Baba-Amer, Y.; Souvannanorath, S.; Malfatti, E.; Relaix, F.; bencze, M.; Authier, F. J.
10.1101/2021.12.16.472927 — cell biology — Posted on 2021-12-16
1666 Invasive slipper limpets Crepidula fornicata act like a sink, rather than source, of Vibrio spp.
Quinn, E. A.; Malkin, S.; Thomas, J.; Poole, R.; Davies, C. E.; Rowley, A. F.; Coates, C. J.
10.1101/2021.12.16.472931 — microbiology — Posted on 2021-12-16
1667 Structure of the hepatitis C virus E1E2 glycoprotein complex
Torrents de la Pena, A.; Sliepen, K.; Eshun-Wilson, L.; Newby, M.; Allen, J. D.; Koekkoek, S.; Zon, I.; Chumbe, A.; Crispin, M.; Schinkel, J.; Lander, G. C.; Sanders, R. W.; Ward, A. B.
10.1101/2021.12.16.472992 — immunology — Posted on 2021-12-16
1668 Discrete LAT condensates encode antigen information from single pMHC:TCR binding events
McAffee, D. B.; O'Dair, M. K.; Lin, J. J.; Low-Nam, S. T.; Wilhelm, K. B.; Kim, S.; Morita, S.; Groves, J. T.
10.1101/2021.12.16.472676 — biophysics — Posted on 2021-12-16
1669 Nfeature: A platform for computing features of nucleotide sequences
Mathur, M.; Patiyal, S.; Dhall, A.; Jain, S.; Tomer, R.; Arora, A.; Raghava, G. P. S.
10.1101/2021.12.14.472723 — bioinformatics — Posted on 2021-12-16
1670 Understanding p300-transcription factor interactions using sequence variation and hybridization
Hobor, F.; Hegedus, Z.; Ibarra, A. A.; Petrovicz, V. L.; Bartlett, G. J.; Sessions, R. B.; Wilson, A. J.; Edwards, T. A.
10.1101/2021.12.16.472944 — biochemistry — Posted on 2021-12-16
1672 High-affinity nanobodies as tools for structural and functional studies on mammalian Arc
Markusson, S.; Hallin, E. I.; Bustad, H. J.; Raasakka, A.; Xu, J.; Muruganandam, G.; Loris, R.; Bramham, C.; Kursula, P.
10.1101/2021.12.16.472929 — biochemistry — Posted on 2021-12-16
1674 Controlling homology-directed repair outcomes in human stem cells with dCas9
Skarnes, W. C.; Ning, G.; Giansiracusa, S.; Cruz, A. S.; Blauwendraat, C.; Saavedra, B.; Holden, K.; Cookson, M. R.; Ward, M. E.; McDonough, J. A.
10.1101/2021.12.16.472942 — genetics — Posted on 2021-12-16
1675 Modified forms of easyCLIP
Porter, D. F.; Garg, R. M.; Meyers, R. M.; Miao, W.; Ducoli, L.; Zarnegar, B. J.; Khavari, P. A.
10.1101/2021.12.15.472862 — molecular biology — Posted on 2021-12-16
1677 Transcriptomic responses of the human kidney to acute injury at single cell resolution
Hinze, C.; Kocks, C.; Leiz, J.; Karaiskos, N.; Boltengagen, A.; Skopnik, C. M.; Klocke, J.; Hardenberg, J.-H.; Stockmann, H.; Gotthardt, I.; Obermayer, B.; Haghverdi, L.; Wyler, E.; Landthaler, M.; Bachmann, S.; Hocke, A. C.; Corman, V.; Busch, J.; Schneider, W.; Himmerkus, N.; Bleich, M.; Eckardt, K.-U.; Enghard, P.; Rajewsky, N.; Schmidt-Ott, K. M.
10.1101/2021.12.15.472619 — molecular biology — Posted on 2021-12-16
1678 Comparative genomics of Acinetobacter baumannii and therapeutic bacteriophages from a patient undergoing phage therapy
Liu, M.; Hernandez-Morales, A. C.; Clark, J.; Le, T. T.; Biswas, B.; Bishop-Lilly, K. A.; Henry, M. S.; Quinones, J.; Hamilton, T.; Schooley, R.; Salka, S.; Young, R. F.; Gill, J. J.
10.1101/2021.12.14.472731 — microbiology — Posted on 2021-12-16
1680 Human TLR4 and noncanonical inflammasome differ in their ability to respond to distinct lipid A variants
Alexander-Floyd, J.; Bass, A. R.; Harberts, E. M.; Grubaugh, D.; Buxbaum, J. D.; Brodsky, I. E.; Ernst, R. K.; Shin, S.
10.1101/2021.12.16.472937 — immunology — Posted on 2021-12-16
1681 Treatment with IgM-enriched intravenous immunoglobulins (IgM-IVIg) enhances clearance of stroke-associated bacterial lung infection
McCulloch, L.; Harris, A. J.; Malbon, A.; Daniels, M. J. D.; Younas, M.; Grainger, J. R.; Allan, S. M.; Smith, C. J.; McColl, B. W.
10.1101/2021.12.16.472965 — immunology — Posted on 2021-12-16
1682 The neural cell adhesion molecule NrCAM regulates development of hypothalamic tanycytes
Moore, A.; Chinnaiya, K.; Kim, D. W.; Brown, S.; Stewart, I.; Robins, S.; Dowsett, G.; Muir, C.; Travaglio, M.; Lewis, J. E.; Ebling, F.; Blackshaw, S.; Furley, A.; Placzek, M.
10.1101/2021.12.15.472761 — neuroscience — Posted on 2021-12-16
1684 Flv3A facilitates O2 photoreduction and affects H2 photoproduction independently of Flv1A in diazotrophic Anabaena filaments
Santana Sanchez, A.; Nikkanen, L.; Toth, G.; Ermakova, M.; Kosourov, S.; Walter, J.; He, M.; Aro, E.-M.; Allahverdiyeva, Y.
10.1101/2021.12.15.472848 — plant biology — Posted on 2021-12-16
1685 Syndecan-1 is overexpressed in human thoracic aneurysm but is dispensable for the disease progression in vivo
Zalghout, S.; Vo, S.; Arocas, V.; Jadoui, S.; Hamade, E.; Badran, B.; Oudar, O.; Charnaux, N.; Boulaftali, Y.; Bouton, M.-C.; Richard, B.
10.1101/2021.12.16.471096 — pathology — Posted on 2021-12-16
1688 Human Mitochondrial AAA+ ATPase SKD3/CLPB forms Nucleotide-Stabilized Dodecamers
Spaulding, Z.; Thevarajan, I.; Schrag, L. G.; Zubcevic, L.; Zolkiewska, A.; Zolkiewski, M.
10.1101/2021.12.16.472980 — biochemistry — Posted on 2021-12-16
1690 The 677C>T variant in methylenetetrahydrofolate reductase causes morphological and functional cerebrovascular deficits in mice
Reagan, A. M.; Christensen, K. E.; Rozen, R.; Bedwell, A. A.; Eldridge, K.; Speedy, R.; Figueiredo, L. L.; Persohn, S. A.; Bottiglieri, T.; Sasner, M.; Territo, P. R.; Graham, L. C.; Howell, G. R.
10.1101/2021.12.16.472805 — genetics — Posted on 2021-12-16
1692 Centromere identity is dependent on nuclear spatial organization
Wu, W.; McHugh, T.; Kelly, D. A.; Pidoux, A. L.; Allshire, R. C.
10.1101/2021.12.16.473016 — cell biology — Posted on 2021-12-16
1696 Emergence of compensatory mutations reveal the importance of electrostatic interactions between HIV-1 integrase and genomic RNA
Shema Mugisha, C.; Dinh, T.; Tenneti, K.; Eschbach, J. E.; Davis, K.; Gifford, R.; Kvaratskhelia, M.; Kutluay, S.
10.1101/2021.12.16.472884 — microbiology — Posted on 2021-12-16
1697 SMAD4 and TGFβ are architects of inverse genetic programs during fate-determination of antiviral memory CD8 T cells
Chandiran, K.; Suarez-Ramirez, J.; Hu, Y.; Ugur, Z.; Jellison, E. R.; low, J.-S.; McDonald, B.; Kaech, S. M.; Cauley, L. S.
10.1101/2021.12.16.472993 — immunology — Posted on 2021-12-16
1698 IFN-γ-independent control of M. tuberculosis requires CD4 T cell-derived GM-CSF and activation of HIF-1α
Van Dis, E.; Morrison, H. M.; Fines, D. M.; Babirye, J. P.; McCann, L. H.; Rawal, S.; Cox, J. S.; Stanley, S. A.
10.1101/2021.12.16.473015 — immunology — Posted on 2021-12-16
1699 Attenuated transcriptional response to pro-inflammatory cytokines in schizophrenia hiPSC-derived neural progenitor cells
Bhat, A.; Irizar, H.; Raval, P.; Duarte, R. R.; Dutan Polit, L.; Powell, T.; Deans, P. J. M.; Shum, C.; Nagy, R.; McAlonan, G.; Iyegbe, C. O.; Price, J.; Bramon, E.; Bhattacharyya, S.; Vernon, A. C.; Srivastava, D. P.
10.1101/2021.12.15.472107 — neuroscience — Posted on 2021-12-16
1700 Spatially bivariate EEG-neurofeedback can manipulate interhemispheric rebalancing of M1 excitability
Hayashi, M.; Okuyama, K.; Mizuguchi, N.; Hirose, R.; Okamoto, T.; Kawakami, M.; Ushiba, J.
10.1101/2021.12.15.472763 — neuroscience — Posted on 2021-12-16
1705 Shape variability of the central sulcus in the developing brain: a longitudinal descriptive and predictive study in preterm infants.
de Vareilles, H.; Riviere, D.; Sun, Z.; Fischer, C.; Leroy, F.; Neumane, S.; Stopar, N.; Eijsermans, R.; Ballu, M.; Tataranno, M. L.; Benders, M.; Mangin, J.-F.; Dubois, J.
10.1101/2021.12.15.472770 — neuroscience — Posted on 2021-12-16
1709 Leukocyte cytokine responses in adult patients with mitochondrial DNA defects
Karan, K. R.; Trumpff, C.; Cross, M.; Englestad, K. M.; Marsland, A. L.; McGuire, P.; Hirano, M.; Picard, M.
10.1101/2021.12.13.472449 — immunology — Posted on 2021-12-16
1711 A reusable benchmark of brain-age prediction from M/EEG resting-state signals
Engemann, D. A.; Mellot, A.; Hoechenberger, R.; Banville, H.; Sabbagh, D.; Gemein, L.; Ball, T.; Gramfort, A.
10.1101/2021.12.14.472691 — neuroscience — Posted on 2021-12-16
1715 Clemastine induces an impairment in developmental myelination
Palma, A.; Chara, J. C.; Otxoa-Amezaga, A.; Planas, A.; Matute, C.; Perez-Samartin, A.; Domercq, M.
10.1101/2021.12.14.472570 — neuroscience — Posted on 2021-12-16
1716 An explainable self-attention deep neural network for detecting mild cognitive impairment using multi-inputbdigital drawing tasks
Ruengchaijatuporn, N.; Chatnuntawech, I.; Teerapittayanon, S.; Sriswasdi, S.; Itthipuripat, S.; Chotibut, T.; Chunharas, C.
10.1101/2021.12.15.472738 — neuroscience — Posted on 2021-12-16
1719 SARS-CoV-2 variants of concern are dependent on IFITM2 for efficient replication in human lung cells
Nchioua, R.; Schundner, A.; Kmiec, D.; Prelli Bozzo, C.; Zech, F.; Koepke, L.; Graf, A.; Krebs, S.; Blum, H.; Frick, M.; Sparrer, K. M. J.; Kirchhoff, F.
10.1101/2021.12.06.471527 — immunology — Posted on 2021-12-16
1720 Non-rapid eye movement sleep and wake neurophysiology in schizophrenia
Kozhemiako, N.; Wang, J.; Jiang, C.; Wang, L. A.; Gai, G.-c.; Zou, K.; Wang, Z.; Yu, X.-m.; Zhou, L.; Li, S.; Guo, Z.; Law, R. G.; Coleman, J.; Mylonas, D.; Shen, L.; Wang, G.; Tan, S.; Qin, S.; Huang, H.; Murphy, M.; Stickgold, R.; Manoach, D. S.; Zhou, Z.; Zhu, W.; Hall, M.-H.; Purcell, S. M.; Pan, J.
10.1101/2021.12.13.472475 — neuroscience — Posted on 2021-12-16
1721 Loss of Cohesin regulator PDS5A reveals repressive role of Polycomb loops
Bsteh, D.; Moussa, H. F.; Michlits, G.; Yelagandula, R.; Wang, J.; Elling, U.; Bell, O.
10.1101/2021.12.15.472841 — molecular biology — Posted on 2021-12-16
1723 Historical specimens and the limits of subspecies phylogenomics in the New World quails (Odontophoridae)
Salter, J. F.; Hosner, P. A.; Tsai, W. L.; McCormack, J. E.; Braun, E. L.; Kimball, R. T.; Brumfield, R. T.; Faircloth, B. C.
10.1101/2021.11.18.468700 — evolutionary biology — Posted on 2021-12-16
1725 SARS-CoV-2 variants of concern remain dependent on IFITM2 for efficient replication in human lung cells
Nchioua, R.; Schundner, A.; Kmiec, D.; Prelli Bozzo, C.; Zech, F.; Koepke, L.; Graf, A.; Krebs, S.; Blum, H.; Frick, M.; Sparrer, K. M.; Kirchhoff, F.
10.1101/2021.11.17.468942 — microbiology — Posted on 2021-12-16
1726 Identification of a promiscuous conserved CTL epitope within the SARS-CoV-2 spike protein
Jiang, S.; Wu, S.; Zhao, G.; He, Y.; Guo, X.; Zhang, Z.; Hou, J.; Ding, Y.; Cheng, A.; Wang, B.
10.1101/2021.11.21.469172 — immunology — Posted on 2021-12-16
1727 SARS-CoV-2 Spike protein activates TMEM16F-mediated platelet pro-coagulant activity
Cappelletto, A.; Allan, H. E.; Crescente, M.; Schneider, E.; Bussani, R.; Ali, H.; Secco, I.; Vodret, S.; Simeone, R.; Mascaretti, L.; Zacchigna, S.; Warner, T. D.; Giacca, M.
10.1101/2021.12.14.472668 — pathology — Posted on 2021-12-16
1728 RB1 loss triggers dependence on ESRRG in retinoblastoma
Field, M. G.; Kuznetsoff, J. N.; Zhang, M.; Dollar, J. J.; Durante, M. A.; Sayegh,, Y.; Decatur, C.; Kurtenbach, S.; Pelaez, D.; Harbour, J. W.
10.1101/2021.12.15.472842 — cancer biology — Posted on 2021-12-16
1734 Nanotrap Particles Improve Nanopore Sequencing of SARS-CoV-2 and Other Respiratory Viruses
Andersen, P. D.; Barksdale, S.; Barclay, R. A.; Smith, N.; Fernandes, J.; Goldfarb, D.; Barbero, R.; Jones-Roe, T.; Besse, K.; Dunlap, R.; Kelly, R.; Miao, S.; Ruhunusiri, C.; Munns, A.; Mosavi, S.; Munns, D.; Sanson, L.; Saswata, S.; Swahn, O.; Hull, K.; White, D.; Kolb, K.; Noroozi, F.; Seelam, J.; Patnaik, A.; Lepene, B.
10.1101/2021.12.08.471814 — microbiology — Posted on 2021-12-16
1735 An RNA-binding switch drives ribosome biogenesis and tumorigenesis downstream of RAS oncogene
Azman, M. S.; Dodel, M.; Capraro, F.; Faraway, R.; Dermit, M.; Fan, W.; Ule, J.; Mardakheh, F. K.
10.1101/2021.12.16.472890 — cancer biology — Posted on 2021-12-16
1736 Structural dynamics of SARS-CoV-2 nucleocapsid protein induced by RNA binding
Ribeiro-Filho, H. V.; Jara, G. E.; Batista, F. A. H.; Schleder, G. R.; Tonoli, C. C.; Soprano, A. S.; Guimaraes, S. L.; Borges, A. C.; Cassago, A.; Bajgelman, M. C.; Marques, R. E.; Trivella, D. B. B.; Franchini, K. G.; Figueira, A. C. M.; Benedetti, C. E.; Lopes-de-Oliveira, P. S.
10.1101/2021.08.27.457964 — biophysics — Posted on 2021-12-16
1739 A glyphosate-based herbicide cross-selects for antibiotic resistance genes in bacterioplankton communities
Barbosa da Costa, N.; Hebert, M.-P.; Fugere, V.; Terrat, Y.; Fussmann, G.; Gonzalez, A.; Shapiro, B. J.
10.1101/2021.12.13.472531 — microbiology — Posted on 2021-12-16
1743 PHASE: A MATLAB Based Program for the Analysis of Drosophila Phase, Activity, and Sleep under Entrainment
Persons, J.; Abhilash, L.; Lopatkin, A. J.; Roelofs, A.; Bell, E. V.; Fernandez, M. d. l. P.; Shafer, O. T.
10.1101/2021.12.14.472617 — animal behavior and cognition — Posted on 2021-12-16
1744 Selective pressure on membrane proteins drives the evolution of Helicobacter pylori Colombian subpopulations
Guevara Tique, A. A.; Torres, R. C.; Castro Valencia, F. L.; Suarez, J. J.; Criollo Rayo, A. A.; Bravo, M. M.; Carvajal Carmona, L. G.; Echeverry de Polanco, M. M.; Bohorquez Lozano, M. E.; Torres, J.
10.1101/2021.12.14.472690 — genomics — Posted on 2021-12-16
1745 Spontaneous parthenogenesis in the parasitoid wasp Cotesia typhae: low frequency anomaly or evolving process?
Capdevielle Dulac, C.; Benoist, R.; Paquet, S.; Calatayud, P.-A.; Obonyo, J.; Kaiser, L.; Mougel, F.
10.1101/2021.12.13.472356 — evolutionary biology — Posted on 2021-12-16
1747 Evolution of miRNA binding sites and regulatory networks in cichlids
Mehta, T. K.; Penso-Dolfin, L.; Nash, W. K.; Roy, S.; Di Palma, F.; Haerty, W.
10.1101/2021.12.14.472604 — molecular biology — Posted on 2021-12-16
1748 A putative cap binding protein and the methyl phosphate capping enzyme Bin3/MePCE function in telomerase biogenesis.
Paez-Moscoso, D. J.; Ho, D. V.; Pan, L.; Hildebrand, K.; Jensen, K. L.; Levy, M. J.; Florens, L.; Baumann, P.
10.1101/2021.12.15.472819 — molecular biology — Posted on 2021-12-16
1753 Regulation of effector gene expression as concerted waves in Leptosphaeria maculans: a two-players game
Clairet, C.; Gay, E. J.; Porquier, A.; Blaise, F.; Marais, C.-L.; Balesdent, M.-H.; Rouxel, T.; Soyer, J. L.; Fudal, I.
10.1101/2021.12.15.472773 — plant biology — Posted on 2021-12-16
1754 Inhibition of the sodium-dependent HCO3 -transporter SLC4A4, produces a cystic fibrosis-like airway disease phenotype.
Saint-Criq, V.; Guequen, A.; Philp, A. R.; Villanueva, S.; Apablaza, T.; Fernandez-Moncada, I.; Mansilla, A.; Delpiano, L.; Ruminot, I.; Carrasco, C.; Gray, M.; Flores, C. A.
10.1101/2021.12.14.472535 — physiology — Posted on 2021-12-16
1757 skater: An R package for SNP-based Kinship Analysis, Testing, and Evaluation
Turner, S. D.; Nagraj, V. P.; Scholz, M.; Jessa, S.; Acevedo, C.; Ge, J.; Woerner, A. E.; Budowle, B.
10.1101/2021.07.21.453083 — bioinformatics — Posted on 2021-12-16
1758 Namco: A microbiome explorer
Dietrich, A.; Matchado, M. S.; Zwiebel, M.; Ölke, B.; Lauber, M.; Lagkouvardos, I.; Baumbach, J.; Haller, D.; Brandl, B.; Skurk, T.; Hauner, H.; Reitmeier, S.; List, M.
10.1101/2021.12.15.471754 — bioinformatics — Posted on 2021-12-16
1759 Physiochemically distinct SU-8 surfaces tailor Xylella fastidiosa cell-surface holdfast and colonization
Anbumani, S.; Silva, A. M. d.; Alaferdov, A.; Santos, M. V. P. d.; Carvalho, I. G. B.; Silva, M. d. S. e.; Moshkalev, S.; Carvalho, H. F.; Souza, A. A. d.; Cotta, M. A.
10.1101/2021.12.14.472636 — bioengineering — Posted on 2021-12-16
1762 Differing Associations between Optic Nerve Head Strains and Visual Field Loss in Normal- and High-Tension Glaucoma Subjects
Chuangsuwanich, T.; Tun, T. A.; Wang, X.; Chin, Z. Y.; Panda, S. K.; Buist, M.; Strouthidis, N.; Perera, S.; Nongpiur, M.; Aung, T.; Girard, M. J. A.
10.1101/2021.12.15.472712 — bioengineering — Posted on 2021-12-16
1764 Population genomics reveal distinct and diverging populations of An. minimus in Cambodia - a widespread malaria vector in Southeast Asia
St. Laurent, B.; Harding, N.; Deason, N.; Oy, K.; Loeun, C. S.; Sunly, R.; Sary, M.; Nhep, S.; Drury, E.; Rockett, K.; Sovannaroth, S.; Goncalves, S.; Kwiatkowski, D.; Miles, A.
10.1101/2021.11.11.468219 — genomics — Posted on 2021-12-16
1769 Genetic coupling of life-history and aerobic performance in Atlantic salmon
Prokkola, J. M.; Asheim, E. R.; Morozov, S.; Bangura, P.; Erkinaro, J.; Ruokolainen, A.; Primmer, C. R.; Aykanat, T.
10.1101/2021.08.23.457324 — evolutionary biology — Posted on 2021-12-16
1770 Nest aggregations of wild bees and apoid wasps in urban pavements: a street life to be promoted in urban planning
Noel, G.; Van Keymeulen, V.; Barbier, Y.; Smets, S.; Van Damme, O.; Colinet, G.; Ruelle, J.; Francis, F.
10.1101/2021.12.15.472743 — ecology — Posted on 2021-12-16
1772 From Diversity to Complexity: Microbial Networks in Soils
Guseva, K.; Darcy, S.; Simon, E.; Alteio, L. V.; Montesinos-Navarro, A.; Kaiser, C.
10.1101/2021.12.14.472586 — ecology — Posted on 2021-12-16
1773 The dual role of N6-methyladenosine on mouse maternal RNAs and 2-cell specific RNAs revealed by ULI-MeRIP sequencing
Wu, Y.; Xu, X.; Qi, M.; Chen, C.; Zhang, M.; Yan, R.; Kou, X.; Zhao, Y.; Liu, W.; Zhang, M.; Yi, C.; Li, Y.; Wang, H.; Shen, B.; Gao, Y.; Gao, S.
10.1101/2021.12.13.472368 — developmental biology — Posted on 2021-12-16
1774 Prdm16 and Notch functionally and physically interact during artery development
Beerens, M.; Van Wauwe, J.; Craps, S.; KC, A.; Finck, C.; Daems, M.; Leigh, N.; MacRae, C. A.; Luttun, A.
10.1101/2021.12.05.471275 — developmental biology — Posted on 2021-12-16
1777 De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals
Tetreau, G.; Sawaya, M. R.; De Zitter, E.; Andreeva, E. A.; Banneville, A.-S.; Schibrowsky, N.; Coquelle, N.; Brewster, A. S.; Grunbein, M. L.; Nass-Kovacs, G.; Hunter, M. S.; Kloos, M.; Sierra, R. G.; Schiro, G.; Qiao, P.; Stricker, M.; Bideshi, D.; Young, I. D.; Zala, N.; Engilberge, S.; Gorel, A.; Signor, L.; Teulon, J.-M.; Hilpert, M.; Foucar, L.; Bielecki, J.; de Wijn, R.; Sato, T.; Kirkwood, H.; Bean, R.; Letrun, R.; Batyuk, A.; Snigireva, I.; Fenel, D.; Schubert, R.; Canfield, E. J.; Alba, M. M.; Laporte, F.; Despres, L.; Bacia, M.; Roux, A.; Chapelle, C.; Riobe, F.; Maury, O.; Ling, W.
10.1101/2021.12.15.472578 — molecular biology — Posted on 2021-12-16
1780 A mixture of innate cryoprotectants is key for cryopreservation of a drosophilid fly larva.
Kucera, L.; Moos, M.; Stetina, T.; Korbelova, J.; Vodrazka, P.; Des Marteaux, L.; Grgac, R.; Hula, P.; Rozsypal, J.; Faltus, M.; Simek, P.; Sedlacek, R.; Kostal, V.
10.1101/2021.12.15.472769 — physiology — Posted on 2021-12-16
1781 A simple and direct method to define clonal selection in somatic mosaicism
Koerber, V.; Ansari-Pour, N.; Jakobsen, N. A.; Moore, R.; Claudino, N.; Metzner, M.; Usukhbayar, B.; Salazar, M. A.; Newman, S.; Kendrick, B. J.; Taylor, A. H.; Afinowi-Luitz, R.; Gundle, R.; Watkins, B.; Wheway, K.; Beazley, D.; Carr, A. J.; Vyas, P.; Hoefer, T.
10.1101/2021.12.15.472780 — cancer biology — Posted on 2021-12-16
1782 Short senolytic or senostatic interventions rescue progression of radiation-induced frailty and premature ageing in mice
Fielder, E.; Wan, T.; Alimohammadiha, G.; Ishaq, A.; Low, E.; Weigand, M. B.; Kelly, G.; Parker, C.; Griffin, B.; Jurk, D.; Korolchuk, V.; von Zglinicki, T.; Miwa, S.
10.1101/2021.12.15.472756 — cancer biology — Posted on 2021-12-16
1786 Automated identification of chicken distress vocalisations using deep learning models
MAO, A.; Giraudet, C.; LIU, K.; De Almeida Nolasco, I.; Xie, Z.; Xie, Z.; Gao, Y.; Theobald, J.; Bhatta, D.; Stewart, R.; G. McElligott, A.
10.1101/2021.12.15.472774 — animal behavior and cognition — Posted on 2021-12-16
1787 Most primary olfactory neurons have individually neutral effects on behavior
Tumkaya, T.; Burhanudin, S.; Khalilnezhad, A.; Stewart, J.; Choi, H.; Claridge-Chang, A.
10.1101/2021.06.10.447838 — animal behavior and cognition — Posted on 2021-12-16
1789 Comparative Analysis and Data Provenance for 1,113 Bacterial Genome Assemblies
Yarmosh, D. A.; Lopera, J. G.; Puthuveetil, N. P.; Combs, P. F.; Reese, A. L.; Tabron, C.; Pierola, A. E.; Duncan, J.; Greenfield, S. R.; Marlow, R.; King, S.; Riojas, M. A.; Bagnoli, J.; Benton, B.; Jacobs, J. L.
10.1101/2021.12.14.472616 — genomics — Posted on 2021-12-16
1792 COEVOLUTION WITH SPATIALLY STRUCTURED RICE LANDRACES MAINTAINS MULTIPLE GENERALIST LINEAGES IN THE RICE BLAST PATHOGEN
Ali, S.; Gladieux, P.; Ravel, S.; Adreit, H.; Meusnier, I.; Milazzo, J.; Cross-Arteil, S.; Bonnot, F.; Jin, B.; Dumartinet, T.; Charriat, F.; Lassangne, A.; He, X.; Tharreau, D.; Huang, H.; Morel, J.-B.; Fournier, E.
10.1101/2021.12.15.472812 — evolutionary biology — Posted on 2021-12-16
1798 Single-cell resolution unravels spatial alterations in metabolism, transcriptome and epigenome of ageing liver
Nikopoulou, C.; Kleinenkuhnen, N.; Parekh, S.; Sandoval, T.; Schneider, F.; Giavalisco, P.; Bozukova, M.; Vesting, A. J.; Altmueller, J.; Wunderlich, T.; Kondylis, V.; Tresch, A.; Tessarz, P.
10.1101/2021.12.14.472593 — cell biology — Posted on 2021-12-16
1799 TRPM4 is required for calcium oscillations downstream from the stretch-activated TRPV4 channel
Yarishkin, O.; Phuong, T. T.; Vazquez-Chona, F.; Bertrand, J. A.; Redmon, S.; Lakk, M.; Baumann`, J. M.; Rudzitis, C. N.; Hwang, E. M.; Overby, D.; Krizaj, D.
10.1101/2021.12.15.472700 — cell biology — Posted on 2021-12-16
1800 Pseudomonas aeruginosa utilises host-derived polyamines to facilitate antimicrobial tolerance
Hasan, C. M.; Green, A.; Cox, A. A.; White, J.; Jones, T.; Winstanley, C.; Kadioglu, A.; Wright, M.; Neill, D. R.; Fothergill, J. L.
10.1101/2021.12.15.472801 — microbiology — Posted on 2021-12-16
1803 A mean-field toolbox for spiking neuronal network model analysis
Layer, M.; Senk, J.; Essink, S.; van Meegen, A.; Bos, H.; Helias, M.
10.1101/2021.12.14.472584 — neuroscience — Posted on 2021-12-16
1805 Metabolic alterations in a Drosophila model of Parkinson's disease based on DJ-1 deficiency
Solana-Manrique, C.; Sanz, F. J.; Torregrosa, I.; Palomino-Schatzlein, M.; Hernandez-Oliver, C.; Pineda, A.; Paricio, N.
10.1101/2021.12.15.472768 — neuroscience — Posted on 2021-12-16
1806 Neural mechanism of experience-dependent sensory gain control in C. elegans
Ikejiri, Y.; Tanimoto, Y.; Fujita, K.; Hiramatsu, F.; Yamazaki, S. J.; Endo, Y.; Iwatani, Y.; Fujimoto, K.; Kimura, K. D.
10.1101/2021.12.14.472713 — neuroscience — Posted on 2021-12-16
1808 Intrinsic instability of the dysbiotic microbiome revealed through dynamical systems inference at scale
Gibson, T. E.; Kim, Y.; Acharya, S.; Kaplan, D. E.; DiBenedetto, N.; Lavin, R.; Berger, B.; Allegretti, J. R.; Bry, L.; Gerber, G. K.
10.1101/2021.12.14.469105 — systems biology — Posted on 2021-12-16
1812 Intact rDNA arrays of Potentilla-origin detected in Erythronium nucleus suggest recent eudicot-to-monocot horizontal transfer
Bartha, L.; Mandakova, T.; Kovarik, A.; Bulzu, P. A.; Rodde, N.; Mahelka, V.; Lysak, M. A.; Fustier, M. A.; Safar, J.; Capal, P.; Keresztes, L.; Banciu, H. L.
10.1101/2021.12.15.472635 — plant biology — Posted on 2021-12-16
1813 Differential requirement for the EDS1 catalytic triad in A. thaliana and N. benthamiana
Zoennchen, J.; Gantner, J.; Lapin, D.; Barthel, K.; Eschen-Lippold, L.; Zantop, S.; Kretschmer, C.; Parker, J. E.; Guerois, R.; Stuttmann, J.
10.1101/2021.12.15.472806 — plant biology — Posted on 2021-12-16
1816 Qualifying a human Liver-Chip for predictive toxicology: Performance assessment and economic implications
Ewart, L.; Apostolou, A.; Briggs, S. A.; Carman, C. V.; Chaff, J. T.; Heng, A. R.; Jadalannagari, S.; Janardhanan, J.; Jang, K.-J.; Joshipura, S. R.; Kadam, M.; Kanellias, M.; Kujala, V. J.; Kulkarni, G.; Le, C. Y.; Lucchesi, C.; Manatakis, D.; Maniar, K. K.; Quinn, M. E.; Ravan, J. S.; Rizos, A. C.; Sauld, J. F. K.; Sliz, J.; Tien-Street, W.; Trinidad, D. R.; Velez, J.; Wendell, M.; Mahalingaiah, P. K.; Ingber, D. E.; Levner, D.
10.1101/2021.12.14.472674 — pharmacology and toxicology — Posted on 2021-12-16
1818 A Precision Medicine Approach to Metabolic Therapy for Breast Cancer in Mice
Akingbesote, N. D.; Norman, A.; Zhu, W.; Halberstam, A. A.; Zhang, X.; Foldi, J. R.; Lustberg, M. B.; Perry, R. J.
10.1101/2021.12.15.472809 — cancer biology — Posted on 2021-12-16
1819 Caveats to deep learning approaches to RNA secondary structure prediction
Flamm, C.; Wielach, J.; Wolfinger, M. T.; Badelt, S.; Lorenz, R.; Hofacker, I.
10.1101/2021.12.14.472648 — bioinformatics — Posted on 2021-12-16
1822 Epigenetic remodeling during monolayer cell expansion reduces therapeutic potential
Scott, A.; Casas, E.; Schneider, S. E.; Swearingen, A.; Van Den Elzen, C.; Seelbinder, B.; Barthold, J.; Kugel, J.; Stern, J. L.; Foster, K.; Emery, N.; Brumbaugh, J.; Neu, C.
10.1101/2021.12.14.472696 — bioengineering — Posted on 2021-12-16
1824 The Blepharisma stoltei macronuclear genome: towards the origins of whole genome reorganization
Singh, M.; Seah, B. K. B.; Emmerich, C.; Singh, A.; Woehle, C.; Huettel, B.; Byerly, A.; Stover, N. A.; Sugiura, M.; Harumoto, T.; Swart, E. C.
10.1101/2021.12.14.471607 — genomics — Posted on 2021-12-16
1825 A framework for research into continental ancestry groups of the UK Biobank
Constantinescu, A.-E.; Mitchell, R. E.; Zheng, J.; Bull, C. J.; Timpson, N. J.; Amulic, B.; Vincent, E. E.; Hughes, D. A.
10.1101/2021.12.14.472589 — genomics — Posted on 2021-12-16
1827 GiPS: Genomics-informed parent selection uncovers the breeding value of wheat genetic resources
Schulthess, A. W.; Kale, S. M.; Liu, F.; Zhao, Y.; Philipp, N.; Rembe, M.; Jiang, Y.; Beukert, U.; Serfling, A.; Himmelbach, A.; Fuchs, J.; Oppermann, M.; Weise, S.; Boeven, P. H. G.; Schacht, J.; Longin, C. F. H.; Kollers, S.; Pfeiffer, N.; Korzun, V.; Lange, M.; Scholz, U.; Stein, N.; Mascher, M.; Reif, J. C.
10.1101/2021.12.15.472759 — genomics — Posted on 2021-12-16
1829 Standing genetic variation fuels rapid evolution of herbicide resistance in blackgrass
Kersten, S.; Chang, J.; Huber, C. D.; Voichek, Y.; Lanz, C.; Hagmaier, T.; Lang, P.; Lutz, U.; Hirschberg, I.; Lerchl, J.; Porri, A.; Van de Peer, Y.; Schmid, K.; Weigel, D.; Rabanal, F. A.
10.1101/2021.12.14.472587 — evolutionary biology — Posted on 2021-12-16
1832 Areas Important for Ecological Connectivity Throughout Canada
Pither, R.; O'Brien, P.; Brennan, A.; Hirsh-Pearson, K.; Bowman, J.
10.1101/2021.12.14.472649 — ecology — Posted on 2021-12-16
1833 Prolyl-hydroxylase inhibitor-induced regeneration of alveolar bone and soft tissue in a mouse model of ligature-induced periodontitis
Zebrowitz, E.; Kajikawa, T.; Bedelbaeva, K.; Bollinger, S.; Zhang, Y.; Sarfatti, D.; Cheng, J.; Messersmith, P. B.; Hajishengallis, G.; Heber-Katz, E.
10.1101/2021.12.14.472623 — developmental biology — Posted on 2021-12-16
1836 Plexins Promote Hedgehog Signaling Through Their Cytoplasmic GAP Activity
Pinskey, J. M.; Hoard, T. M.; Zhao, X.-F.; Franks, N. E.; Frank, Z. C.; McMellen, A. N.; Giger, R. J.; Allen, B. L.
10.1101/2021.12.15.472757 — developmental biology — Posted on 2021-12-16
1837 MIG-23 is involved in sperm migration in Ascaris suum
Wang, X.; Wang, Q.; He, R.; Zhang, Q.; Shan, J.; Zhao, Y.; Chen, L.
10.1101/2021.12.14.472724 — cell biology — Posted on 2021-12-16
1839 Interferon-γ Exposure of Human iPSC-derived Neurons Alters Major Histocompatibility Complex I and Synapsin I Protein Expression
Pavelinek, A.; Matuleviciute, R.; Sichlinger, L.; Dutan Polit, L.; Armeniakos, N.; Vernon, A. C.; Srivastava, D. P.
10.1101/2021.12.15.472810 — neuroscience — Posted on 2021-12-16
1841 Proteome-wide cellular thermal shift assay reveals novel crosstalk between brassinosteroid and auxin signaling
Lu, Q.; Zhang, Y.; Hellner, J.; Xu, X.; Pauwels, J.; Giannini, C.; Ma, Q.; Dejonghe, W.; Han, H.; Van de Cotte, B.; Impens, F.; Gevaert, K.; Friml, J.; De Smet, I.; Molina, D. M.; Russinova, E.
10.1101/2021.12.14.472597 — plant biology — Posted on 2021-12-16
1844 Genomic and transcriptomic somatic alterations of hepatocellular carcinoma in non-cirrhotic livers
Skidmore, Z. L.; Kunisaki, J.; Lin, Y.; Cotto, K. C.; Barnell, E. K.; Hundal, J.; Krysiak, K.; Magrini, V.; Trani, L.; Walker, J. R.; Fulton, R.; Brunt, E.; Miller, C. A.; Wilson, R. K.; Mardis, E. R.; Griffith, M.; Chapman, W.; Griffith, O. L.
10.1101/2021.12.14.472689 — cancer biology — Posted on 2021-12-16
1846 Label-free Cell Tracking Enables Collective Motion Phenotyping in Epithelial Monolayers
Gu, S.; Lee, R. M.; Benson, Z.; Ling, C.; Vitolo, M. I.; Martin, S. S.; Chalfoun, J.; Losert, W.
10.1101/2021.12.14.472148 — biophysics — Posted on 2021-12-16
1854 pop-1/TCF, ref-2/ZIC and T-box factors regulate the development of anterior cells in the C. elegans embryo
Rumley, J. D.; Preston, E. A.; Cook, D.; Peng, F. L.; Zacharias, A. L.; Wu, L.; Jileaeva, I.; Murray, J. I.
10.1101/2021.12.14.472681 — genetics — Posted on 2021-12-15
1859 Harmonizing Functional Connectivity Reduces Scanner Effects in Community Detection
Chen, A. A.; Srinivasan, D.; Pomponio, R.; Fan, Y.; Nasrallah, I.; Resnick, S.; Beason-Held, L.; Davatzikos, C.; Satterthwaite, T.; Bassett, D. S.; Shinohara, R. T.; Shou, H.
10.1101/2021.12.03.469269 — neuroscience — Posted on 2021-12-16
1860 Robust, sensitive, and quantitative single-cell proteomics based on ion mobility filtering
Woo, J.; Clair, G. C.; Williams, S. M.; Feng, S.; Tsai, C.-F.; Moore, R. J.; Chrisler, W. B.; Smith, R. D.; Kelly, R. T.; Pasa-Tolic, L.; Ansong, C.; Zhu, Y.
10.1101/2021.01.30.428333 — systems biology — Posted on 2021-12-15
1861 The eukaryotic translation initiation factor eIF4E reprogrammes the splicing machinery anddrives alternative splicing
Ghram, M.; Morris, G.; Culjkovic-Kraljacic, B.; Gendron, P.; Skrabanek, L.; Revuelta, M. V.; Cerchietti, L.; Guzman, M.; Borden, K.
10.1101/2021.12.07.471666 — cancer biology — Posted on 2021-12-15
1866 Spontaneous parthenogenesis in the parasitoid wasp Cotesia typhae: low frequency anomaly or evolving process?
Capdevielle Dulac, C.; Benoist, R.; Paquet, S.; Calatayud, P.-A.; Obonyo, J.; Kaiser, L.; Mougel, F.
10.1101/2021.12.13.472356 — evolutionary biology — Posted on 2021-12-15
1867 Sequence-space expansion is driven by the emergence of new signaling pathways
Garber, M. E.; Frank, V.; Kazakov, A. E.; Zhang, H.; Incha, M. R.; Keasling, J. D.; Rajeev, L.; Mukhopadhyay, A.
10.1101/2020.09.30.321588 — evolutionary biology — Posted on 2021-12-15
1871 A comprehensive approach for artifact-free sample preparation and assessment of mitochondrial morphology in tissue and cultured cells
Hinton, A.; Katti, P.; Christensen, T. A.; Mungai, M.; Shao, J.; Zhang, L.; Trushin, S.; Alghanem, A.; Jaspersen, A.; Geroux, R. E.; Neikirk, K.; Biete, M.; Garza Lopez, E.; Vue, Z.; Beasley, H.; Marshall, A.; Hicsasmaz, I.; Edmonds, R. A. C.; Dajles, A.; Koo, Y. D.; Bacevac, S.; Salisbury, J. L.; Pereira, R. O.; Glancy, B.; Trushina, E.; Abel, E. D.
10.1101/2021.06.27.450055 — cell biology — Posted on 2021-12-15
1872 Bacterial quorum sensing allows graded and bimodal cellular responses to variations in population density
Rattray, J. B.; Thomas, S. A.; Wang, Y.; Molotkova, E.; Gurney, J.; Varga, J.; Brown, S. P.
10.1101/850297 — microbiology — Posted on 2021-12-15
1873 Differential and defective expression of Koala Retrovirus indicate complexity of host and virus evolution
Tarlinton, R. E.; Legione, A.; Sarker, N.; Fabijan, J.; Meers, J.; McMichael, L.; Simmons, G.; Owen, H.; Seddon, J.; Dick, G.; Ryder, J.; Hemmatzedah, F.; Trott, D.; Speight, N.; Holmes, N.; Loose, M.; Emes, R.
10.1101/211466 — microbiology — Posted on 2021-12-15
1877 Asymmetric Structure of the Native Rhodobacter sphaeroides Dimeric LH1-RC Complex
Tani, K.; Kanno, R.; Kikuchi, R.; Kawamura, S.; Nagashima, K. V. P.; Hall, M.; Takahashi, A.; Yu, L.-J.; Kimura, Y.; Madigan, M. T.; Mizoguchi, A.; Humbel, B. M.; Wang-Otomo, Z.- Y.
10.1101/2021.12.14.472695 — biochemistry — Posted on 2021-12-15
1880 Evolution of stickleback spines through independent cis-regulatory changes at HOXDB
Wucherpfennig, J. I.; Howes, T. R.; Au, J. N.; Au, E. H.; Roberts Kingman, G. A.; Brady, S. D.; Herbert, A. L.; Reimchen, T. E.; Bell, M. A.; Lowe, C. B.; Dalziel, A. C.; Kingsley, D. M.
10.1101/2021.12.14.472698 — evolutionary biology — Posted on 2021-12-15
1881 DNMT3A knockouts in human iPSCs prevent de novo DNA methylation and reveal growth advantage during hematopoietic differentiation
Cypris, O.; Franzen, J.; Frobel, J.; Glueck, P.; Kuo, C.-C.; Schmitz, S.; Nuechtern, S.; Zenke, M.; Wagner, W.
10.1101/2021.12.15.472782 — cell biology — Posted on 2021-12-15
1882 Arl15 upregulates the TGFβ family signaling by promoting the assembly of the Smad-complex
Shi, M.; Tie, H. C.; Mahajan, D.; Sun, X.; Zhou, Y.; Boh, B. K.; Vardy, L.; Lu, L.
10.1101/2021.12.14.472727 — cell biology — Posted on 2021-12-15
1884 Evolution of miRNA binding sites and regulatory networks in cichlids
Mehta, T. K.; Penso-Dolfin, L.; Nash, W. K.; Roy, S.; Di Palma, F.; Haerty, W. `
10.1101/2021.12.14.472604 — molecular biology — Posted on 2021-12-15
1886 The ColR/S two-component system is a conserved determinant of host association across Pseudomonas species
Wiesmann, C. L.; Zhang, Y.; Alford, M.; Thoms, D.; Dostert, M.; Wilson, A.; Pletzer, D.; Hancock, R. E. W.; Haney, C. H.
10.1101/2021.12.14.472530 — microbiology — Posted on 2021-12-15
1888 SARS-CoV-2 Spike protein activates TMEM16F-mediated platelet pro-coagulant activity
Giacca, M.; Cappelletto, A.; Allan, H. E.; Crescente, M.; Schneider, E.; Bussani, R.; Ali, H.; Secco, I.; Vodret, S.; Simeone, R.; Mascaretti, L.; Zacchigna, S.; Warner, T. D.
10.1101/2021.12.14.472668 — pathology — Posted on 2021-12-15
1891 Comparison of extraction methods for intracellular metabolomics
Andresen, C.; Boch, T.; Gegner, H. M.; Mechtel, N.; Narr, A.; Birgin, E.; Rasbach, E.; Rahbari, N. N.; Trumpp, A.; Poschet, G.; Huebschmann, D.
10.1101/2021.12.15.470649 — biochemistry — Posted on 2021-12-15
1892 Photoaffinity capture compounds to profile the Magic Spot Nucleotide interactomes
Haas, T. M.; Laventie, B. J.; Lagies, S.; Harter, C.; Prucker, I.; Ritz, D.; Batcha, R. S.; Qiu, D.; Huettel, W.; Andexer, J.; Jenal, U.; Jessen, H. J.
10.1101/2021.12.15.472736 — biochemistry — Posted on 2021-12-15
1895 NAD+ capping of RNA in Archaea and Mycobacteria
Ruiz-Larrabeiti, O.; Benoni, R.; Zemlianski, V.; Hanisakova, N.; Schwarz, M.; Brezovska, B.; Benoni, B.; Hnilicova, J.; Kaberdin, V. R.; Cahova, H.; Vitezova, M.; Prevorovsky, M.; Krasny, L.
10.1101/2021.12.14.472595 — molecular biology — Posted on 2021-12-15
1896 METTL3 facilitates hepatic fibrosis progression via m6A-YTHDF2 dependent silencing of GPR161
Pan, X.; Bi, Y.; Chen, M.; Qian, Z.; Wang, L.; You, H.; Liu, L.; Zhang, Z.; Meng, X.-M.; Huang, C.; Li, J.
10.1101/2021.12.15.472749 — molecular biology — Posted on 2021-12-15
1897 Development and Characterization of Recombinant Vesicular Stomatitis Virus (rVSV)-based Bivalent Vaccine Against COVID-19 Delta Variant and Influenza Virus
Ao, Z.; Jing Ouyang, M.; Olukitibi, T. A.; Warner, B.; Vendramelli, R.; Truong, T.; Zhang, M.; Kung, S.; Fowke, K. R.; Kobasa, D.; Yao, X.
10.1101/2021.12.14.472657 — microbiology — Posted on 2021-12-15
1898 The African Swine Fever Isolate ASFV-Kenya-1033-IX is highly virulent and stable after growth in the wild boar cell line WSL
Hemmink, J. D.; Abkallo, H. M.; Henson, S. P.; Khazalwa, E. M.; Oduor, B.; Lacasta, A.; Okoth, E.; Fuchs, W.; Bishop, R. P.; Steinaa, L.
10.1101/2021.12.15.472778 — microbiology — Posted on 2021-12-15
1899 Bacterial origin of thymidylate and folate metabolism in Asgard Archaea
Filee, J.; Becker, H. J.; Mellottee, L.; LI, Z.; Lambry, J.-C.; Liebl, U.; Myllykallio, H. J.
10.1101/2021.12.15.472764 — microbiology — Posted on 2021-12-15
1901 Generating Electricity from Water Evaporation Through Microbial Biofilms
Liu, X.; Ueki, T.; Gao, H.; Woodard, T. L.; Nevin, K. P.; Fu, T.; Fu, S.; Sun, L.; Lovley, D. R.; Yao, J.
10.1101/2021.12.14.472618 — microbiology — Posted on 2021-12-15
1902 Linear plasmids in Klebsiella and other Enterobacteriaceae
Hawkey, J.; Cottingham, H.; Tokolyi, A.; Wick, R. R.; Judd, L. M.; Cerdeira, L.; de Oliveira Garcia, D.; Wyres, K. L.; Holt, K. E.
10.1101/2021.12.14.472703 — microbiology — Posted on 2021-12-15
1905 Soluble MAC is primarily released from MAC-resistant bacteria that potently convert complement component C5
Doorduijn, D. J.; Lukassen, M. V.; van 't Wout, M. F. L.; Franc, V.; Ruyken, M.; Bardoel, B. W.; Heck, A. J. R.; Rooijakkers, S. H. M.
10.1101/2021.12.15.472789 — microbiology — Posted on 2021-12-15
1906 The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies
Yu, D. S.; Outram, M. A.; Smith, A.; McCombe, C. L.; Khambalkar, P. B.; Rima, S. A.; Sun, X.; Ma, L.; Ericsson, D. J.; Jones, D. A.; Williams, S. J.
10.1101/2021.12.14.472499 — plant biology — Posted on 2021-12-15
1910 Embryo-scale epithelial buckling forms a propagating furrow that initiates gastrulation
Fierling, J.; John, A.; Delorme, B.; Torzynski, A.; Blanchard, G. B.; Lye, C. M.; Malandain, G.; Sanson, B.; Etienne, J.; Marmottant, P.; Quilliet, C.; Rauzi, M.
10.1101/2021.12.14.472566 — developmental biology — Posted on 2021-12-15
1912 Link between aging and atheroprotection in Mif-deficient atherosclerotic mice
Krammer, C. M.; Yang, B.; Reichl, S.; Bolini, V.; Schulte, C.; Noels, H.; El Bounkari, O.; Kapurniotu, A.; Weber, C.; Sarajo, M.; Bernhagen, J.
10.1101/2021.12.14.471281 — immunology — Posted on 2021-12-15
1913 Considerable escape of SARS-CoV-2 variant Omicron to antibody neutralization
Planas, D.; Saunders, N.; Maes, P.; Benhassine, F. G.; Planchais, C.; Porrot, F.; Staropoli, I.; Lemoine, F.; Pere, H.; Veyer, D.; Puech, J.; Rodary, J.; Bolland, W. H.; Buchrieser, J.; Baele, G.; Dellicour, S.; Raymenants, J.; Gorissen, S.; Geenen, C.; Vanmechelen, B.; Wawina, T.; Marti, J.; Cuypers, L.; Seve, A.; Hocqueloux, L.; Prazuck, T.; Loriere, E. S.; REY, F.; Bruel, T.; Mouquet, H.; Andre, E.; Schwartz, O.
10.1101/2021.12.14.472630 — immunology — Posted on 2021-12-15
1914 Prefrontal top-down projections control context-dependent strategy selection
Gschwend, O.; Yang, T.; van de Lisdonk, D.; Zhang, X.; Sharma, R.; Li, B.
10.1101/2021.12.14.472559 — neuroscience — Posted on 2021-12-15
1915 High content screening and computational prediction reveal viral genes that suppress innate immune response
Ng, T. L.; Olson, E. J.; Yoo, T. Y.; Weiss, H. S.; Koide, Y.; Koch, P. D.; Rollins, N. J.; Mach, P.; Meisinger, T.; Bricken, T.; Chang, T. Z.; Molloy, C. W.; Zurcher, J.; Mitchison, T.; Glass, J. I.; Marks, D. S.; Way, J. C.; Silver, P. A.
10.1101/2021.12.14.472572 — systems biology — Posted on 2021-12-15
1917 Combined SHP2 and ERK inhibition for the treatment of KRAS-driven Pancreatic Ductal Adenocarcinoma
Ciecielski, K. J.; Mulero-Sanchez, A.; Berninger, A.; Canas, L. R.; Bosma, A.; Gorgulu, K.; Wu, N.; Diakopoulos, K. N.; Kaya-Aksoy, E.; Ruess, D. A.; Kabacaoglu, D.; Schmidt, F.; Heinemann, L.; Fan, Y.; Thijssen, B.; van de Ven, M.; Proost, N.; Kossatz, S.; Weber, W. A.; Sainz, B.; Bernards, R.; Algul, H.; Lesina, M.; Mainardi, S.
10.1101/2021.12.14.472574 — cancer biology — Posted on 2021-12-15
1918 Combined free energy calculation and machine learning methods for understanding ligand unbinding kinetics
Badaoui, M.; Buigues, P. J.; Berta, D.; Mandana, G. M.; Gu, H.; Földes, T.; Dickson, C. J.; Hornak, V.; Kato, M.; Molteni, C.; Parsons, S. D.; Rosta, E.
10.1101/2021.09.08.459492 — biophysics — Posted on 2021-12-15
1919 SARS-CoV-2 variants impact RBD conformational dynamics and ACE2 accessibility
Valerio, M. F.; Borges-Araujo, L.; Melo, M. N.; Lousa, D.; Soares, C. M.
10.1101/2021.11.30.470470 — biophysics — Posted on 2021-12-15
1922 The dual function monoclonal antibodies VIR-7831 and VIR-7832 demonstrate potent in vitro and in vivo activity against SARS-CoV-2
Cathcart, A. L.; Havenar-Daughton, C.; Lempp, F. A.; Ma, D.; Schmid, M.; Agostini, M. L.; Guarino, B.; Di iulio, J.; Rosen, L.; Tucker, H.; Dillen, J.; Subramanian, S.; Sloan, B.; Bianchi, S.; Wojcechowskyj, J.; Zhou, J.; Kaiser, H.; Chase, A.; Lauron, E.; Montiel-Ruiz, M.; Spreafico, R.; Noack, J.; Czudnochowski, N.; Sahakyan, A.; Pinto, D.; Saliba, C.; Culap, K.; Delotta, E.; Park, A.; Cameroni, E.; Ledoux, S.; Werts, A.; Colas, C.; Soriaga, L.; Telenti, A.; Purcell, L. A.; Hwang, S.; Snell, G.; Virgin, H. W.; Corti, D.; Hebner, C. M.
10.1101/2021.03.09.434607 — immunology — Posted on 2021-12-15
1924 From Deer-to-Deer: SARS-CoV-2 is efficiently transmitted and presents broad tissue tropism and replication sites in white-tailed deer
Martins, M.; Boggiatto, P. M.; Buckley, A.; Cassmann, E. D.; Falkenberg, S.; Caserta, L. C.; Fernandes, M. H. V.; Kanipe, C.; Lager, K.; Palmer, M. V.; Diel, D. G.
10.1101/2021.12.14.472547 — microbiology — Posted on 2021-12-15
1925 Striking Antibody Evasion Manifested by the Omicron Variant of SARS-CoV-2
Liu, L.; Iketani, S.; Guo, Y.; Chan, J. F.-W.; Wang, M.; Liu, L.; Luo, Y.; Chu, H.; Huang, Y.; Nair, M. S.; Yu, J.; Chik, K. K.-H.; Yuen, T. T.-T.; Yoon, C.; To, K. K.-W.; Chen, H.; Yin, M. T.; Sobieszczyk, M. E.; Huang, Y.; Wang, H. H.; Sheng, Z.; Yuen, K.-Y.; Ho, D. D.
10.1101/2021.12.14.472719 — microbiology — Posted on 2021-12-15
1926 Viral infection engenders bona fide and bystander lung memory B cell subsets through permissive selection
Gregoire, C.; Spinelli, L.; Villazala-Merino, S.; Gil, L.; Moussa, M.; Dong, C.; Zarubica, A.; Fallet, M.; Navarro, J.-M.; Malissen, B.; Milpied, P.; Gaya, M.
10.1101/2021.12.14.472614 — immunology — Posted on 2021-12-15
1927 Long-read RNA sequencing identifies polyadenylation elongation and differential transcript usage of host transcripts during SARS-CoV-2 in vitro infection
Chang, J. J.-Y.; Gleeson, J.; Rawlinson, D.; Pitt, M. E.; De Paoli-Iseppi, R.; Zhou, C.; Mordant, F. L.; Londrigan, S. L.; Clark, M. B.; Subbarao, K.; Stinear, T. P.; Coin, L. J. M.
10.1101/2021.12.14.472725 — immunology — Posted on 2021-12-15
1929 Potential inhibitors for blocking the interaction of the coronavirus SARS-CoV-2 spike protein and its host cell receptor ACE2
Li, C.; Zhou, H.; Guo, L.; Xie, D.; He, H.; Zhang, H.; Liu, Y.; Peng, L.; Zheng, L.; Lu, W.; Mei, Y.; Liu, Z.; Huang, J.; Wang, M.; Shu, D.; Ding, L.; Lang, Y.; Luo, F.; Wang, J.; Huang, B.; Huang, P.; Gao, S.; Chen, J.; Qian, C.-N.
10.1101/2021.12.14.472545 — pharmacology and toxicology — Posted on 2021-12-15
1930 Learning Single-Cell Perturbation Responses using Neural Optimal Transport
Bunne, C.; Stark, S. G.; Gut, G.; Sarabia del Castillo, J.; Lehmann, K.-V.; Pelkmans, L.; Krause, A.; Ratsch, G.
10.1101/2021.12.15.472775 — bioinformatics — Posted on 2021-12-15
1933 Genomic determinants of Furin cleavage in diverse European SARS-related bat coronaviruses
Sander, A.-L.; Moreira-Soto, A.; Yordanov, S.; Toplak, I.; Balboni, A.; Ameneiros, R. S.; Corman, V. M.; Drosten, C.; Drexler, J. F.
10.1101/2021.12.15.472779 — evolutionary biology — Posted on 2021-12-15
1934 Metalloproteinase-dependent and TMPRSS2-independnt cell surface entry pathway of SARS-CoV-2 requires the furin-cleavage site and the S2 domain of spike protein
Yamamoto, M.; Gohda, J.; Kobayashi, A.; Tomita, K.; Hirayama, Y.; Koshikawa, N.; Seiki, M.; Semba, K.; Akiyama, T.; Kawaguchi, Y.; Inoue, J.-i.
10.1101/2021.12.14.472513 — microbiology — Posted on 2021-12-15
1936 Selection-driven adaptation to the extreme Antarctic environment in the Emperor penguin
Pirri, F.; Ometto, L.; Fuselli, S.; Fernandes, F. A. N.; Ancona, L.; Le Bohec, C.; Zane, L.; Trucchi, E.
10.1101/2021.12.14.471946 — evolutionary biology — Posted on 2021-12-15
1937 Fast, live-cell imaging of 15 intracellular compartments by deep learning segmentation of super-resolution data
Zhanghao, K.; Li, m.; Chen, X.; Liu, W.; Wang, Y.; Wu, Z.; Shan, C.; Wu, J.; Zhang, Y.; Xi, P.; Jin, D.
10.1101/2021.12.13.472520 — cell biology — Posted on 2021-12-15
1938 Genetic, parental and lifestyle factors influence telomere length
Andreu-Sanchez, S.; Aubert, G.; Ripoll-Cladellas, A.; Henkelman, S.; Zhernakova, D. V.; Sinha, T.; Kurilshikov, A.; Cenit, M. C.; Bonder, M. J.; Lifelines cohort study, ; Franke, L.; Wijmenga, C.; Fu, J.; van der Wijst, M. G. P.; Mele, M.; Lansdorp, P.; Zhernakova, A.
10.1101/2021.12.14.472541 — cell biology — Posted on 2021-12-15
1939 GZMKhigh CD8+ T effector memory cells are associated with CD15high neutrophil abundance in early-stage colorectal tumors and predict poor clinical outcome.
Tiberti, S.; Catozzi, C.; Scirgolea, C.; Croci, O.; Ballerini, M.; Cagnina, D.; Soriani, C.; Macandog, A. D.; Nava Lauson, C. B.; Bertalot, G.; Petz, W. L.; Ravenda, S. P.; Licursi, V.; Paci, P.; Rasponi, M.; Fazio, N.; Ren, G.; Fumagalli-Romario, U.; Schaefer, M. H.; Campaner, S.; Lugli, E.; Nezi, L.; MANZO, T. o.
10.1101/2021.12.14.472046 — immunology — Posted on 2021-12-15
1941 Sex-specific topology of the nociceptive circuit shapes dimorphic behavior in C. elegans
Pechuk, V.; Goldman, G.; Salzberg, Y.; Chaubey, A. H.; Bola, R. A.; Hoffman, J. R.; Endreson, M. L.; Miller, R. M.; Reger, N. J.; Portman, D. S.; Ferkey, D. M.; Schneidman, E.; Oren-Suissa, M.
10.1101/2021.12.14.472335 — neuroscience — Posted on 2021-12-15
1945 Noninvasive Stimulation of Peripheral Nerves using Temporally-Interfering Electrical Fields
Botzanowski, B.; Donahue, M. J.; Silvera Ejneby, M.; Gallina, A. L.; Ngom, I.; MISSEY, F.; Acerbo, E.; Byun, D.; Carron, R.; Cassara, A.; Neufeld, E.; Jirsa, V.; Olofsson, P.; Glowacki, E. D.; Williamson, A.
10.1101/2021.12.14.472557 — neuroscience — Posted on 2021-12-15
1946 Genuine Selective Caspase-2 Inhibition with new Irreversible Small Peptidomimetics
Bosc, E.; Anastasie, J.; Soualmia, F.; Coric, P.; Kim, J. Y.; Lacin, G.; Duplus, E.; Tixador, P.; Brugg, b.; Reboud-Ravaux, M.; Bouaziz, S.; Karin, M.; El Amri, C.; Jacotot, E. D.
10.1101/2021.12.13.472505 — pharmacology and toxicology — Posted on 2021-12-15
1948 GREPore-seq: A Robust Workflow to Detect Changes after Gene Editing through Long-range PCR and Nanopore Sequencing
Quan, Z.-J.; Li, S.-A.; Yang, Z.-X.; Zhao, J.-J.; Li, G.-H.; Zhang, F.; Wen, W.; Cheng, T.; Zhang, X.-B.
10.1101/2021.12.13.472514 — bioinformatics — Posted on 2021-12-15
1951 A novel framework for analysis of the shared genetic background of correlated traits
Svishcheva, G. R.; Tiys, E. S.; Elgaeva, E. E.; Feoktistova, S. G.; Timmers, P. R. H. J.; Sharapov, S. Z.; Axenovich, T. I.; Tsepilov, Y. A.
10.1101/2021.12.13.472525 — bioinformatics — Posted on 2021-12-15
1954 A calibrated functional patch clamp assay to enhance clinical variant interpretation in KCNH2-related long QT syndrome
Jiang, C.; Richardson, E.; Farr, J.; Hill, A. P.; Ullah, R.; Kroncke, B. M.; Harrison, S. M.; Thomson, K. L.; Ingles, J.; Vandenberg, J. I.; Ng, C. A.
10.1101/2021.12.13.472492 — genetics — Posted on 2021-12-15
1955 Morphological variation and phylogeny of Karenia selliformis (Gymnodiniales, Dinophyceae) in an intensive cold-water algal bloom in eastern Hokkaido, Japan in September-November 2021
Iwataki, M.; Lum, W. M.; Kuwata, K.; Takahashi, K.; Arima, D.; Kuribayashi, T.; Kosaka, Y.; Hasegawa, N.; Watanabe, T.; Shikata, T.; Isada, T.; Orlova, T. Y.; Sakamoto, S.
10.1101/2021.12.13.472515 — ecology — Posted on 2021-12-15
1956 LRRFIP2 modulates the response to hypoxia during embryonic cardiogenesis
Ben Driss, L.; Houbron, C.; Britto, F.; Schmitt, A.; Le-gall, M.; Daubas, P.; Maire, P.
10.1101/2021.12.14.472540 — developmental biology — Posted on 2021-12-15
1957 Multimodal IVA fusion for detection of linked neuroimaging biomarkers
Silva, R. F.; Damaraju, E.; Li, X.; Kochonov, P.; Belger, A.; Ford, J. M.; McEwen, S.; Mathalon, D. H.; Mueller, B. A.; Potkin, S. G.; Preda, A.; Turner, J. A.; van Erp, T. G. M.; Adali, T.; Calhoun, V. D.
10.1101/2021.12.13.472507 — neuroscience — Posted on 2021-12-15
1959 Broad misappropriation of developmental splicing profile by cancer in multiple organs
Singh, A.; Rajeevan, A.; Gopalan, V.; Agrawal, P.; Day, C.-P.; Hannenhalli, S.
10.1101/2021.12.13.472504 — cancer biology — Posted on 2021-12-15
1963 BRG1 defines a genomic subset of inflammatory genes transcriptionally controlled by the glucocorticoid receptor
Mechtidou, A.; Greulich, F.; Strickland, B. A.; Jouffe, C.; Cernilogar, F. M.; Schotta, G.; Uhlenhaut, N. H.
10.1101/2021.12.13.472398 — genomics — Posted on 2021-12-15
1965 Trends in Pacific Canadian groundfish stock status
Anderson, S. C.; Connors, B. M.; English, P. A.; Forrest, R. E.; Haigh, R.; Holt, K. R.
10.1101/2021.12.13.472502 — ecology — Posted on 2021-12-15
1972 Spontaneous adaptation of ion selectivity in a bacterial flagellar motor
Ridone, P.; Ishida, T.; Lin, A.; Humphreys, D. T.; Giannoulatou, E.; Sowa, Y.; Baker, M. A.
10.1101/2021.01.26.427765 — microbiology — Posted on 2021-12-15
1975 A bacterial effector counteracts host autophagy by promoting degradation of an autophagy component
Leong, J. X.; Raffeiner, M.; Spinti, D.; Langin, G.; Franz-Wachtel, M.; Guzman, A. R.; Kim, J.-G.; Pandey, P.; Minina, A. E. A.; Macek, B.; Hafren, A.; Bozkurt, T. O.; Mudgett, M. B.; Boernke, F.; Hofius, D.; Uestuen, S.
10.1101/2021.03.17.435853 — plant biology — Posted on 2021-12-15
1977 A DROSOPHILA CIRCUIT FOR HABITUATION OVERRIDE
Trisal, S.; Aranha, M. M.; Chodankar, A.; Vijayraghavan, K.; Ramaswami, M.
10.1101/2021.09.11.459900 — neuroscience — Posted on 2021-12-15
1982 ProteinPrompt: a webserver for predicting protein-protein interactions
Canzler, S.; Fischer, M.; Ulbricht, D.; Ristic, N.; Hildebrand, P. W.; Staritzbichler, R.
10.1101/2021.09.03.458859 — bioinformatics — Posted on 2021-12-15
1987 A role for the locus coeruleus in the modulation of feeding
Sciolino, N. R.; Hsiang, M.; Mazzone, C. M.; Wilson, L. R.; Plummer, N. W.; Amin, J.; Smith, K. G.; McGee, C. A.; Fry, S. A.; Yang, C. X.; Powell, J. M.; Bruchas, M. R.; Kravitz, A. V.; Cushman, J. D.; Krashes, M. J.; Cui, G.; Jensen, P.
10.1101/2019.12.18.881599 — neuroscience — Posted on 2021-12-15
1988 Severe fever with thrombocytopenia syndrome virus and parthenogenetic Asian longhorned tick Haemaphysalis longicornis (Acari: Ixodidae)
Zheng, A.; Zhang, Z.; Zhang, G.; Zhan, X.; Zhang, X.; Zhao, C.; Cheng, C.; Li, H.; Yu, T.; Lawrence, K.; Sun, J.; Yang, Z.; Ye, L.; Chu, H.; Wang, Y.; Han, X.; Jia, Y.; Fan, S.; Kanuka, H.; Tanaka, T.; Jenkins, C.; Gedye, K.; Chandra, S.; Price, D. C.; Liu, Q.; Choi, Y. K.
10.1101/2021.10.20.465214 — evolutionary biology — Posted on 2021-12-15
1990 The effects of social environment and the metapleural gland on disease resistance in acorn ants
Scavetta, J. T.; Senula, S. F.; Crowell, D. R.; Siddique, F.; Segrest, J. F.; Dairo, O. A.; Nguyen, L. U.; Pekora, M. S.; Vojvodic Kruse, S.
10.1101/2021.12.14.472662 — ecology — Posted on 2021-12-14
1996 Immune Regulation of Intestinal Stem Cell Proliferation and Differentiation in Drosophila.
Shin, M.; Ferguson, M.; Willms, R. J.; Jones, L. O.; Petkau, K.; Foley, E.
10.1101/721662 — immunology — Posted on 2021-12-14
1998 The Dual Mechanisms of Cognitive Control dataset, a theoretically-guided within-subject task fMRI battery
Etzel, J. A.; Brough, R.; Freund, M. C.; Kizhner, A.; Lin, Y.; Singh, M. F.; Tang, R.; Tay, A.; Wang, A.; Braver, T. S.
10.1101/2021.05.28.446178 — neuroscience — Posted on 2021-12-14
1999 Brain-wide quantification of the supraspinal connectome reveals anatomical correlates to functional recovery after spinal injury
Wang, Z.; Romanski, A.; Mehra, V.; Wang, Y.; Campbell, B. C.; Petsko, G. A.; Tsoulfas, P.; Blackmore, M. G.
10.1101/2021.06.10.447885 — neuroscience — Posted on 2021-12-14
2001 Molecular physiology of pumiliotoxin sequestration in a poison frog
Alvarez-Buylla, A.; Payne, C. Y.; Vidoudez, C.; Trauger, S. A.; O'Connell, L. A.
10.1101/2020.11.03.367524 — physiology — Posted on 2021-12-14
2004 EXPERT: Transfer Learning-enabled context-aware microbial source tracking
Chong, H.; Yu, Q.; Zha, Y.; Xiong, G.; Wang, N.; Huang, X.; Huang, S.; Sun, C.; Wu, S.; Chen, W.; Coelho, L. P.; Ning, K.
10.1101/2021.01.29.428751 — bioinformatics — Posted on 2021-12-14
2006 CandyCollect: At-home saliva sampling for capture of respiratory pathogens
Lee, U. N.; Su, X.; Hieber, D. L.; Tu, W.-c.; McManamen, A. M.; Takezawa, M. G.; Hassan, G. W.; Chan, T. C.; Adams, K. N.; Wald, E. R.; DeMuri, G. P.; Berthier, E.; Theberge, A. B.; Thongpang, S.
10.1101/2021.10.19.464911 — bioengineering — Posted on 2021-12-14
2009 A chromosome-level genome assembly of the European Beech (Fagus sylvatica) reveals anomalies for organelle DNA integration, repeat content and distribution of SNPs
Mishra, B.; Ulaszewski, B.; Meger, J.; Aury, J.-M.; Bodenes, C.; Lesur-Kupin, I.; Pfenninger, M.; DaSilva, C.; Gupta, D. K.; Guichoux, E.; Heer, K.; Labadie, K.; Lalanne, C.; Salse, J.; Opgenoorth, L.; Ploch, S.; LE PROVOST, G.; Scotti, I.; Woetzel, S.; Plomion, C.; Burczyk, J.; Thines, M.
10.1101/2021.03.22.436437 — genomics — Posted on 2021-12-14
2010 Giant Starship elements mobilize accessory genes in fungal genomes
Gluck-Thaler, E.; Ralston, T.; Konkel, Z.; Grabowski Ocampos, C.; Devi Ganeshan, V.; Dorrance, A. E.; Niblack, T. L.; Wood, C. W.; Slot, J. C.; Lopez-Nicora, H. D.; Vogan, A. A.
10.1101/2021.12.13.472469 — genomics — Posted on 2021-12-14
2011 Impact of genomic preselection on subsequent genetic evaluations with ssGBLUP - using real data from pigs
Jibrila, I.; Vandenplas, J.; ten Napel, J.; Bergsma, R.; Veerkamp, R. F.; Calus, M. P. L.
10.1101/2021.06.18.449002 — genetics — Posted on 2021-12-14
2012 pop-1/TCF, ref-2/ZIC and T-box factors regulate the development of anterior cells in the C. elegans embryo
Rumley, J. D.; Preston, E. A.; Cook, D.; Peng, F. L.; Zacharias, A. L.; Wu, L.; Jileaeva, I.; Murray, J. I.
10.1101/2021.12.14.472681 — genetics — Posted on 2021-12-14
2014 Linking plankton size spectra and community composition to carbon export and its efficiency
Serra-Pompei, C.; Ward, B. A.; Pinti, J.; Visser, A. W.; Kiorboe, T.; Andersen, K. H.
10.1101/2021.03.08.434455 — ecology — Posted on 2021-12-14
2015 There and Back to the Present: An Evolutionary Tale on Biological Diversity
Duarte, L.; Nakamura, G.; Debastiani, V.; Maestri, R.; Ramos Pereira, M. J. V. d. C.; Cianciaruso, M.; Diniz-Filho, J. A. F.
10.1101/2021.12.11.472171 — ecology — Posted on 2021-12-14
2016 Pastures and Climate Extremes: Impacts of cool season warming and drought on the productivity of key pasture species in a field experiment
Churchill, A. C.; Zhang, H.; Fuller, K. J.; Amiji, B.; Anderson, I. C.; Barton, C. V. M.; Carrillo, Y.; Catunda, K. L. M.; Chandregowda, M. H.; Igwenagu, C.; Jacob, V.; Kim, G. W. C.; Macdonald, C. A.; Medlyn, B. E.; Moore, B. D.; Pendall, E.; Plett, J. M.; Post, A. K.; Powell, J. R.; Tissue, D. T.; Tjoelker, M. G.; Power, S. A.
10.1101/2020.12.21.423155 — ecology — Posted on 2021-12-14
2018 Modeling lung cell development using human pluripotent stem cells
Ngan, Z.; Quach, H.; Dierolf, J.; Laselva, O.; Lee, J.-A.; Huang, E. N.; Mangos, M.; Xia, S.; Wong, A. P.
10.1101/2021.07.16.452691 — developmental biology — Posted on 2021-12-14
2019 MTG16 (CBFA2T3) regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors
Brown, R. E.; Jacobse, J.; Anant, S. A.; Blunt, K. M.; Chen, B.; Vega, P. N.; Jones, C. T.; Pilat, J. M.; Revetta, F.; Gorby, A. H.; Stengel, K. R.; Choksi, Y. A.; Palin, K.; Piazuelo, M. B.; Washington, M. K.; Lau, K. S.; Goettel, J. A.; Hiebert, S. W.; Short, S. P.; Williams, C. S.
10.1101/2021.11.03.467178 — cell biology — Posted on 2021-12-14
2023 Visual discrimination of optical material properties: a large-scale study
Sawayama, M.; Dobashi, Y.; Okabe, M.; Hosokawa, K.; Koumura, T.; Saarela, T.; Olkkonen, M.; Nishida, S.
10.1101/800870 — neuroscience — Posted on 2021-12-14
2024 Neurocomputational mechanisms of affected beliefs
Müller-Pinzler, L.; Czekalla, N.; Mayer, A. V.; Schröder, A.; Stolz, D. S.; Paulus, F. M.; Krach, S.
10.1101/2021.10.26.465922 — neuroscience — Posted on 2021-12-14
2025 Visual QC Protocol for FreeSurfer Cortical Parcellations from Anatomical MRI
Raamana, P. R.; Theyers, A.; Selliah, T.; Bhati, P.; Arnott, S. R.; Hassel, S.; Nanayakkara, N. D.; Scott, C. J. M.; Harris, J.; Zamyadi, M.; Lam, R. W.; Milev, R.; Mueller, D. J.; Rotzinger, S.; Frey, B. N.; Kennedy, S. H.; Black, S. E.; Lang, A.; Masellis, M.; Symons, S.; Bartha, R.; MacQueen, G. M.; CANBIND Investigator Team, ; ONDRI Study Group, ; Strother, S. C.
10.1101/2020.09.07.286807 — neuroscience — Posted on 2021-12-14
2028 PermaPhosSer: autonomous synthesis of functional, permanently phosphorylated proteins
Zhu, P.; Franklin, R.; Vogel, A.; Stanisheuski, S.; Reardon, P.; Sluchanko, N. N.; Beckman, J. S.; Karplus, P. A.; Mehl, R. A.; Cooley, R. B.
10.1101/2021.10.22.465468 — synthetic biology — Posted on 2021-12-14
2030 Nuclear Progestin Receptor Mediated Linkage of Blood Coagulation and Ovulation
Huang, J.; Chao, S.; Liu, T. D.; Zhao, N. N.; Shavit, J. A.; Zhu, Y.; Chen, S. X.
10.1101/2021.11.08.467707 — physiology — Posted on 2021-12-14
2032 Combinatorial tumor suppressor inactivation efficiently initiates lung adenocarcinoma with therapeutic vulnerabilities
Yousefi, M.; Boross, G.; Weiss, C.; Murray, C. W.; Hebert, J. D.; Cai, H.; Ashkin, E. L.; Karmakar, S.; Andrejka, L.; Chen, L.; Wang, M.; Tsai, M. K.; Lin, W.-Y.; Li, C.; Yakhchalian, P.; Colon, C. I.; Chew, S.-K.; Chu, P.; Swanton, C.; Kunder, C. A.; Petrov, D. A.; Winslow, M. M.
10.1101/2021.10.20.464849 — cancer biology — Posted on 2021-12-14
2036 DyNeuMo Mk-1: Design and Pilot Validation of an Investigational Motion-Adaptive Neurostimulator with Integrated Chronotherapy
Zamora, M.; Toth, R.; Morgante, F.; Ottaway, J.; Gillbe, T.; Martin, S.; Lamb, G.; Noone, T.; Benjaber, M.; Nairac, Z.; Sehgal, D.; Constandinou, T. G.; Herron, J.; Aziz, T. Z.; Gillbe, I.; Green, A. L.; Pereira, E.; Denison, T.
10.1101/2020.09.10.292284 — bioengineering — Posted on 2021-12-14
2039 Hierarchy-guided Neural Networks for Species Classification
Elhamod, M.; Diamond, K. M.; Maga, A. M.; Bakis, Y.; Bart, H. L.; Mabee, P.; Dahdul, W.; Leipzig, J.; Greenberg, J.; Avants, B.; Karpatne, A.
10.1101/2021.01.17.427006 — evolutionary biology — Posted on 2021-12-14
2041 Evolution with private resources reverses some changes from long-term evolution with public resources
van Raay, K.; Stolyar, S.; Sevigny, J.; Muniz Tirado, A.; Draghi, J.; Lenski, R. E.; Marx, C. J.; Kerr, B.; Zaman, L.
10.1101/2021.07.11.451942 — evolutionary biology — Posted on 2021-12-14
2043 MYC uncouples HIF target gene expression from glycolytic flux in hypoxic proliferating primary cells
Copeland, C. A.; Olenchock, B. A.; Ziehr, D.; McGarrity, S.; Leahy, K.; Young, J. D.; Loscalzo, J.; Oldham, W. M.
10.1101/2020.09.21.306464 — cell biology — Posted on 2021-12-14
2044 A calibrated cell-based functional assay to aide classification of MLH1 DNA mismatch repair gene variants
Rath, A.; Radecki, A. A.; Rahman, K.; Gilmore, R. B.; Hudson, J. R.; Cenci, M.; Tavtigian, S. V.; Grady, J. P.; Heinen, C. D.
10.1101/2021.12.14.472580 — cancer biology — Posted on 2021-12-14
2045 RNA binding protein RBM3 augments kissing loop formation with lncRNAs to enhance translational control
Sayed, A. A. A.; Choudhury, S.; Subramaniam, D.; Gunewardena, S.; Ponnurangam, S.; Dandawate, P.; Tawfik, O.; Standing, D.; Padhye, S.; Iwakuma, T.; Umar, S.; Weir, S. J.; Jensen, R. A.; Thomas, S. M.; Anant, S.
10.1101/2021.12.14.472669 — cancer biology — Posted on 2021-12-14
2049 tRForest: a novel random forest-based algorithm for tRNA-derived fragment target prediction
Parikh, R.; Wilson, B.; Marrah, L.; Su, Z.; Saha, S.; Kumar, P.; Huang, F.; Dutta, A.
10.1101/2021.12.13.472430 — bioinformatics — Posted on 2021-12-14
2051 pop-1/TCF, ref-2/ZIC and T-box factors regulate the development of anterior cells in the C. elegans embryo
Rumley, J. D.; Preston, E. A.; Cook, D.; Peng, F. L.; Zacharias, A. L.; Wu, L.; Jileaeva, I.; Murray, J. I.
10.1101/2021.12.14.472681 — genetics — Posted on 2021-12-14
2058 Validated Determination of NRG1 Ig-like Domain Structure by Mass Spectrometry Coupled with Computational Modeling
Abolhasani Khaje, N.; Eletsky, A.; Biehn, S. E.; Mobley, C. K.; Rogals, M. J.; Kim, Y.; Mishra, S. K.; Doerksen, R. J.; Lindert, S.; Prestegard, J.; Sharp, J. S.
10.1101/2021.12.13.472484 — biophysics — Posted on 2021-12-14
2059 ADAPs intrinsically disordered region is an actin sponge regulating T cell motility
Dadwal, N.; Degen, J.; Sticht, J.; Hilal, T.; Wegner, T.; Reichardt, P.; Lyck, R.; Hons, M.; Abadier, M.; Mix, C.; Kuropka, B.; Stephanowitz, H.; Liu, F.; Schraven, B.; Wuelfing, C.; Kliche, S.; Freund, C.
10.1101/2021.12.14.472590 — biochemistry — Posted on 2021-12-14
2060 2.7 A cryo-EM structure of ex vivo RML prion fibrils
Manka, S. W.; Zhang, W.; Wenborn, A.; Betts, J.; Joiner, S.; Saibil, H. R.; Collinge, J.; Wadsworth, J. D. F.
10.1101/2021.12.13.472424 — biochemistry — Posted on 2021-12-14
2061 An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome
Liu, S.; Ezran, C.; Wang, M. F. Z.; Li, Z.; The Tabula Microcebus Consortium, ; Long, J. Z.; De Vlaminck, I.; Wang, S.; Kuo, C.; Epelbaum, J.; Terrien, J.; Krasnow, M. A.; Ferrell, J. E.
10.1101/2021.12.13.472243 — genomics — Posted on 2021-12-14
2062 Elevation drives activity of soil bacteria, but not of bacterial viruses
Merges, D.; Schmidt, A.; Schmitt, I.; Neuschulz, E. L.; Dal Grande, F.; Balint, M.
10.1101/2021.12.14.472558 — ecology — Posted on 2021-12-14
2064 Nanoscale details of mitochondrial fission revealed by cryo-electron tomography
Mageswaran, S. K.; Grotjahn, D. A.; Zeng, X.; Barad, B. A.; Medina, M. A.; Hoang, M. H.; Dobro, M. J.; Chang, Y.-W.; Xu, M.; Yang, W. Y.; Jensen, G. J.
10.1101/2021.12.13.472487 — cell biology — Posted on 2021-12-14
2065 Islet primary cilia motility controls insulin secretion
Cho, J. H.; Li, Z. A.; Zhu, L.; Muegge, B.; Roseman, H.; Utterback, T.; Woodhams, L.; Bayly, P. V.; HUGHES, J.
10.1101/2021.12.14.472629 — cell biology — Posted on 2021-12-14
2066 Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer
Tavoulari, S.; Schirris, T. J. J.; Mavridou, V.; Thangaratnarajah, C.; King, M. S.; Jones, D. T. D.; Ding, S.; Fearnley, I. M.; Kunji, E. R. S.
10.1101/2021.12.14.472537 — molecular biology — Posted on 2021-12-14
2067 Sir2-domain associated short prokaryotic Argonautes provide defence against invading mobile genetic elements through NAD+ depletion
Zaremba, M.; Dakineviciene, D.; Golovinas, E.; Stankunas, E.; Lopatina, A.; Sorek, R.; Manakova, E.; Ruksenaite, A.; Silanskas, A.; Asmontas, S.; Grigaitis, R.; Timinskas, K.; Venclovas, C.; Siksnys, V.
10.1101/2021.12.14.472599 — molecular biology — Posted on 2021-12-14
2069 Multi-virulence and phenotypic spread of Campylobacter jejuni carried by chicken meat in Brazil
Peres, P. A. B. M.; Melo, R. T. d.; Armendaris, P. M.; Barreto, F.; Perin, T. F.; Grazziotin, A. L.; Monteiro, G. P.; Mendonca, E. P.; Lourenzatto, E. C. A.; Bicalho, A. S. M.; Filho, M. d. V.; Buiatte, A. B. G.; Rossi, D. A.
10.1101/2021.12.14.472542 — microbiology — Posted on 2021-12-14
2073 Adaptive changes in the fungal cell wall mediate copper homeostasis
Probst, C.; Garcia-Santamarina, S.; Brooks, J. T.; Van Der Kloet, I.; Thiele, D. J.; Alspaugh, J. A.
10.1101/2021.12.14.472543 — microbiology — Posted on 2021-12-14
2074 Multiple phage resistance systems inhibit infection via SIR2-dependent NAD+ depletion
Garb, J.; Lopatina, A.; Bernheim, A.; Zaremba, M.; Siksnys, V.; Melamed, S.; Leavitt, A.; Millman, A.; Amitai, G.; Sorek, R.
10.1101/2021.12.14.472415 — microbiology — Posted on 2021-12-14
2078 An intrinsic endothelial dysfunction causes cerebral small vessel disease
Quick, S.; Procter, T. V.; Moss, J.; Lawson, A.; Baker, S.; Walton, M.; Mohammad, M.; Mungall, W.; Onishi, A.; Tobola, Z.; Stringer, M.; Jensen, M. A.; Vallatos, A.; Giarratano, Y.; Bernabeu, M. O.; Wardlaw, J.; Williams, A.
10.1101/2021.12.13.472377 — neuroscience — Posted on 2021-12-14
2079 RANK is an independent biomarker of poor prognosis in estrogen receptor-negative breast cancer and a therapeutic target in patient-derived xenografts
Ciscar, M.; Trinidad, E. M.; Perez-Montoyo, H.; Alsaleem, M.; Jimenez-Santos, M. J.; Toss, M.; Sanz-Moreno, A.; Vethencourt, A.; Perez-Chacon, G.; Petit, A.; Soler-Monso, M. T.; Gomez-Miragaya, J.; Gomez-Aleza, C.; Jimenez, M.; Dobrolecki, L. E.; Lewis, M. T.; Bruna, A.; Mouron, S.; Quintela-Fandino, M.; Alshahrour, F.; Martinez-Aranda, A.; Sierra, A.; Green, A. R.; Rakha, E.; Gonzalez-Suarez, E.
10.1101/2021.12.13.470911 — cancer biology — Posted on 2021-12-14
2080 Guiding ATR and PARP inhibitor combinations with chemogenomic screens
Zimmermann, M.; Bernier, C.; Kaiser, B.; Fournier, S.; Li, L.; Desjardin, J.; Skeldon, A.; Rimkunkas, V.; Veloso, A.; Young, J. T.; Roulston, A.; Zinda, M.
10.1101/2021.12.13.472393 — cancer biology — Posted on 2021-12-14
2081 Native SAD Phasing at Room Temperature
Greisman, J. B.; Dalton, K. M.; Sheehan, C. J.; Klureza, M. A.; Hekstra, D. R.
10.1101/2021.12.13.472485 — biophysics — Posted on 2021-12-14
2082 ProteinGLUE: A multi-task benchmark suite for self-supervised protein modeling.
Capel, H.; Weiler, R.; Dijkstra, M. J. J.; Vleugels, R.; Bloem, P.; Feenstra, K. A.
10.1101/2021.12.13.472460 — bioinformatics — Posted on 2021-12-14
2084 Acute and chronic physical activity improve spatial pattern separation in humans
Ramirez Butavand, D.; Rodriguez, M. F.; Cifuentes, M. V.; Miranda, M.; Garcia Bauza, C.; Bekinschtein, P.; Ballarini, F.
10.1101/2021.12.13.472386 — animal behavior and cognition — Posted on 2021-12-14
2087 Giant Starship elements mobilize accessory genes in fungal genomes
Gluck-Thaler, E.; Ralston, T.; Konkel, Z.; Grabowski Ocampos, C.; Devi Ganeshan, V.; Dorrance, A. E.; Niblack, T. L.; Wood, C. W.; Slot, J. C.; Lopez-Nicora, H. D.; Vogan, A. A.
10.1101/2021.12.13.472469 — genomics — Posted on 2021-12-14
2090 Landscape dynamics promoted the evolution of mega-diversity in South American freshwater fishes
Cassemiro, F.; Albert, J. S.; Antonelli, A.; Menegotto, A.; Wuest, R. O.; Coelho, M. T. P.; Bailly, D.; Silva, V. F. B.; Frota, A.; Graca, W. J.; Re, R.; Ramos, T.; Oliveira, A. G.; Dias, M. S.; Colwell, R. K.; Rangel, T. F.; Graham, C. H.
10.1101/2021.12.13.472133 — ecology — Posted on 2021-12-14
2092 PTEN inhibits AMPK to control collective migration
PEGLION, F.; Capuana, L.; Perfettini, I.; braithwaite, B.; Llense, F.; Quissac, E.; Forsberg-Nilsson, K.; Etienne-Manneville, s.
10.1101/2021.12.13.472380 — cell biology — Posted on 2021-12-14
2093 Endothelial-immune crosstalk contributes to vasculopathy in non-alcoholic fatty liver disease
Ng, C.-Y.; Lee, K. L.; Muthiah, M. D.; Wu, K. X.; Chioh, F.; Tan, K.; Soon, G.; Shabbir, A.; Loo, W. M.; Low, Z. S.; Chen, Q.; Tan, N. S.; Ng, H.-H.; Dan, Y. Y.; Cheung, C.
10.1101/2021.12.13.472411 — cell biology — Posted on 2021-12-14
2098 Angle-Tuned Coils: Enabling Building Blocks for High Performance and Multisite TMS Systems
Bagherzadeh, H.; MENG, Q.; Deng, Z.-D.; Lu, H.; Hong, E.; Yang, Y.; Choa, F.-S.
10.1101/2021.12.13.472217 — neuroscience — Posted on 2021-12-14
2100 LKB1 Is Physiologically Required for Sleep from Drosophila to the Mouse
Liu, Z.; Jiang, L.; Li, C.; Li, C.; Yang, J.; Wang, D.; Mao, R.; Rao, Y.
10.1101/2021.12.13.472078 — neuroscience — Posted on 2021-12-14
2101 CRCM5484: A BET- BDII Selective Compound With Differential Anti-Leukemic Drug Potentiation
Carrasco, K.; Montersino, C.; Derviaux, C.; Saez-Ayala, M.; Hoffer, L.; Restouin, A.; Castellano, R.; Casassa, J.; Roche, P.; Pasquier, E.; Combes, S.; Morelli, X.; Collette, Y.; Betzi, S.
10.1101/2021.12.13.472388 — cancer biology — Posted on 2021-12-14
2102 Mechanistic insights of radiation-induced endothelial senescence impelling glioblastoma genomic instability at relapse
Degorre, C.; Renoult, O.; Parplys, A. C.; Awada, H.; Clavreul, A.; Pietri, M.; Oliver, L.; Joalland, N.; Ricoul, M.; Gratas, C.; Vallette, F.; Borgmann, K.; Sabatier, L.; Pecqueur, C.; Paris, F.
10.1101/2021.12.13.472364 — cancer biology — Posted on 2021-12-14
2103 AutoMicroED: A semi-automated MicroED processing pipeline
Powell, S. M.; Novikova, I. V.; Kim, D. N.; Evans, J. E.
10.1101/2021.12.13.472146 — biophysics — Posted on 2021-12-14
2108 Combining δ13C and δ15N from bone and dentine in marine mammal palaeoecological research: insights from toothed whales
Rey-Iglesia, A.; Wilson, T.; Routledge, J.; Skovrind, M.; Garde, E.; Heide-Jorgensen, M. P.; Szpak, P.; Lorenzen, E. D.
10.1101/2021.12.13.472362 — ecology — Posted on 2021-12-14
2109 Monosomy X in isogenic human iPSC-derived trophoblast model impacts expression modules preserved in human placenta
Ahern, D. T.; Bansal, P.; Faustino, I. V.; Kondaveeti, Y.; Glatt-Deeley, H. R.; Banda, E. C.; Pinter, S. F.
10.1101/2021.12.13.472325 — developmental biology — Posted on 2021-12-14
2110 The influence of Janthinobacterium sp. strain SLB01 on the cell culture of primmorphs of the sponge Lubomirskia baicalensis
Chernogor, L. I.; Eliseikina, M. G.; Petrushin, I. S.; Chernogor, E. A.; Khanaev, I. V.; Belikov, S. I.
10.1101/2021.12.13.472427 — microbiology — Posted on 2021-12-14
2112 Spatially distributed computation in cortical circuits
Gepshtein, S.; Pawar, A.; Kwon, S.; Savelev, S.; Albright, T. D.
10.1101/2021.12.13.472322 — neuroscience — Posted on 2021-12-14
2114 A neuron, microglia, and astrocyte triple coculture model to study Alzheimer disease
Luchena, C.; Zuazo-Ibarra, J.; Valero, J.; Matute, C.; Alberdi, E.; Capetillo-Zarate, E.
10.1101/2021.12.13.472367 — neuroscience — Posted on 2021-12-14
2118 Systematic discovery of receptor-ligand biology by engineered cell entry and single-cell genomics
Yu, B.; Shi, Q.; Belk, J. A.; Yost, K. E.; Parker, K. R.; Huang, H.; Lingwood, D.; Davis, M. M.; Satpathy, A. T.; Chang, H. Y.
10.1101/2021.12.13.472464 — genomics — Posted on 2021-12-14
2120 Isolation and Characterization of SARS-CoV-2 strains circulating in Eastern India.
Singh, B.; Avula, K.; Chatterjee, S.; Datey, A.; Ghosh, A.; De, S.; Keshry, S. S.; Ghosh, S.; Suryawanshi, A. R.; Dash, R.; Senapati, S.; Beuria, T. K.; Prasad, P.; Raghav, S.; Swain, R. K.; Parida, A.; Syed, G. H.; Chattopadhyay, S.
10.1101/2021.12.13.472526 — microbiology — Posted on 2021-12-14
2121 High temporal resolution transcriptomic profiling delineates distinct patterns of interferon response following Covid-19 mRNA vaccination and SARS-CoV2 infection
Rinchai, D.; Deola, S.; Zoppoli, G.; Kabeer, B. S. A.; Taleb, S. A.; Pavlovski, I.; Maacha, S.; Gentilcore, G.; Toufiq, M.; Matthew, L.; Liu, L.; Vempalli, F. R.; Mubarak, G.; Lorenz, S.; Sivieri, I.; Cirmena, G.; Dentone, C.; Cuccarolo, P.; Giacobbe, D.; Baldi, F.; Garbarino, A.; Cigolini, B.; Cremonesi, P.; Bedognetti, M.; Ballestrero, A.; Bassetti, M.; Hejblum, B. P.; Augustine, T.; Panhuys, N. V.; Thiebaut, R.; Branco, R.; Chew, T.; Shojaei, M.; Short, K.; Feng, C.; Zughaier, S. M.; Maria, A. D.; Tang, B.; Hssain, A. A.; Bedognetti, D.; Grivel, J.-C.; Chaussabel, D.
10.1101/2021.12.12.472257 — immunology — Posted on 2021-12-14
2122 Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift
Cameroni, E.; Saliba, C.; Bowen, J. E.; Rosen, L. E.; Culap, K.; Pinto, D.; De Marco, A.; Zepeda, S. K.; di Iulio, J.; Zatta, F.; Kaiser, H.; Noack, J.; Farhat, N.; Czudnochowski, N.; Havenar-Daughton, C.; Sprouse, K. R.; Dillen, J. R.; Powell, A. E.; Chen, A.; Maher, C.; Yin, L.; Sun, D.; Soriaga, L.; Gustafsson, C.; Chu, H.; Franko, N. M.; Logue, J.; Iqbal, N. T.; Mazzitelli, I.; Geffner, J.; Grifantini, R.; Gori, A.; Riva, A.; Giannini, O.; Ceschi, A.; Ferrari, P.; Franzetti-Pellanda, A.; Garzoni, C.; Hebner, C.; Purcell, L.; Piccoli, L.; Pizzuto, M. S.; Walls, A. C.; Telenti, A.; Virgin, H
10.1101/2021.12.12.472269 — immunology — Posted on 2021-12-14
2124 Language Models for the Prediction of SARS-CoV-2 Inhibitors
Blanchard, A. E.; Gounley, J.; Bhowmik, D.; Chandra Shekar, M.; Lyngaas, I.; Gao, S.; Yin, J.; Tsaris, A.; Wang, F.; Glaser, J.
10.1101/2021.12.10.471928 — bioinformatics — Posted on 2021-12-14
2125 TopHap: Rapid inference of key phylogenetic structures from common haplotypes in large genome collections with limited diversity
Caraballo-Ortiz, M. A.; Miura, S.; Sanderford, M.; Dolker, T.; Tao, Q.; Weaver, S.; Kosakovsky Pond, S. L.; Kumar, S.
10.1101/2021.12.13.472454 — bioinformatics — Posted on 2021-12-14
2126 Isolation and comparative analysis of antibodies that broadly neutralize sarbecoviruses
Liu, L.; Iketani, S.; Guo, Y.; Casner, R.; Reddem, E.; Nair, M. S.; Yu, J.; Chan, J.; Wang, M.; Cerutti, G.; Li, Z.; Castagna, C.; Corredor, L.; Chu, H.; Yuan, S.; Poon, V.; Chan, C.; Chen, Z.; Luo, Y.; Cunningham, M.; Chavez, A.; Yin, M.; Perlin, D.; Tsuji, M.; Yuen, K.-Y.; Kwong, P.; Sheng, Z.; Huang, Y.; Shapiro, L.; Ho, D. D.
10.1101/2021.12.11.472236 — microbiology — Posted on 2021-12-14
2127 Mucosal and systemic responses to SARS-CoV-2 vaccination in infection naive and experienced individuals
Sajadi, M. M.; Myers, A.; Logue, J.; Saadat, S.; Shokatpour, N.; Quinn, J.; Newman, M.; Deming, M.; Tehrani, Z. R.; Karimi, M.; Abbasi, R.; Crotty, S.; Harris, A. D.
10.1101/2021.12.13.472159 — immunology — Posted on 2021-12-14
2128 CHARM: COVID-19 Health Action Response for Marines - association of antigen-specific interferon-gamma and IL2 responses with asymptomatic and symptomatic infections after a positive qPCR SARS-CoV-2 test
Sedegah, M.; Porter, C.; Hollingdale, M. R.; Ganeshan, H.; Huang, J.; Goforth, C. W.; Belmonte, M.; Belmonte, A.; Weir, D. L.; Lizewski, R. A.; Lizewski, S. E.; Sealfon, S. C.; Jani, V.; Cheng, Y.; Inoue, S.; Velasco, R.; Villasante, E.; Sun, P.; Letizia, A.
10.1101/2021.12.13.472352 — immunology — Posted on 2021-12-14
2129 Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma
Rosenberg, M. I.; Greenstein, E.; Buchkovich, M.; Mikl, M.; Peres, A.; Santoni-Rugiu, E.; Reshef, D.; Salovin, A. J.; Gibbs, D. L.; Irwin, M. S.; Naranjo, A.; Ulitsky, I.; de Alarcon, P. A.; Weigman, V.; Yaari, G.; Panzer, J. A.; Friedman, N.; Maris, J. M.
10.1101/2021.12.14.471886 — cancer biology — Posted on 2021-12-14
2131 Tissue Optimisation Strategies for High Quality Ex Vivo Diffusion Imaging
Barrett, R. L. C.; Cash, D.; Simmons, C.; Kim, E.; Wood, T. C.; Stones, R.; Vernon, A. C.; Catani, M.; Dell'Acqua, F.
10.1101/2021.12.13.472113 — neuroscience — Posted on 2021-12-14
2134 Water droplet-in-oil digestion method for single-cell proteomics
Masuda, T.; Inamori, Y.; Furukawa, A.; Momosaki, K.; Chang, C.-H.; Kobayashi, D.; Ohguchi, H.; Kawano, Y.; Ito, S.; Araki, N.; Ong, S.-E.; Ohtsuki, S.
10.1101/2021.12.13.472378 — systems biology — Posted on 2021-12-14
2135 Genome edited colorectal cancer organoid models reveal distinct microRNA activity patterns across different mutation profiles
Villanueva, J. W.; Kwong, L.; Han, T.; Martinez, S. A.; Pan, F. C.; Shanahan, M. T.; Kanke, M.; Chen, S.; Dow, L. E.; Danko, C. G.; Sethupathy, P.
10.1101/2021.12.13.472432 — cancer biology — Posted on 2021-12-14
2139 The drug-induced phenotypic landscape of colorectal cancer organoids
Betge, J.; Rindtorff, N.; Sauer, J.; Rauscher, B.; Dingert, C.; Gaitantzi, H.; Herweck, F.; Srour, K.; Miersch, T.; Valentini, E.; Hauber, V.; Gutting, T.; Frank, L.; Belle, S.; Gaiser, T.; Buchholz, I.; Jesenofsky, R.; Haertel, N.; Zhan, T.; Fischer, B.; Breitkopf-Heinlein, K.; Burgermeister, E.; Ebert, M. P.; Boutros, M.
10.1101/660993 — genomics — Posted on 2021-12-14
2141 Unveiling effects of growth conditions on crown architecture and growth potential of Scots pine trees
Saarinen, N.; Kankare, V.; Huuskonen, S.; Hynynen, J.; Bianchi, S.; Yrttimaa, T.; Luoma, V.; Junttila, S.; Holopainen, M.; Hyyppa, J.; Vastaranta, M.
10.1101/2021.12.13.472374 — ecology — Posted on 2021-12-14
2144 Structure and dynamics of human disease-complication network
Jiang, X.; Xiong, L.; Bai, L.; Lin, J.; Zhang, J.-F.; Yan, K.; Zhu, J.-Z.; Zheng, B.; Zheng, J.-J.
10.1101/2021.12.13.472342 — bioinformatics — Posted on 2021-12-14
2146 Both Prey and Predator Features Determine Predation Risk and Survival of Schooling Prey
Jolles, J. W.; Sosna, M. M. G.; Mazue, G. P. F.; Twomey, C. R.; Bak-Coleman, J.; Rubenstein, D. I.; Couzin, I. D.
10.1101/2021.12.13.472101 — animal behavior and cognition — Posted on 2021-12-14
2147 Spontaneous parthenogenesis in the parasitoid wasp Cotesia typhae: low frequency anomaly or evolving process?
Capdevielle Dulac, C.; Benoist, R.; Paquet, S.; Calatayud, P.-A.; Obonyo, J.; Kaiser, L.; Mougel, F.
10.1101/2021.12.13.472356 — evolutionary biology — Posted on 2021-12-14
2149 Coevolution of the olfactory organ and its receptor repertoire in ray-finned fishes
Policarpo, M.; Bemis, K. E.; Laurenti, P.; Legendre, L.; Sandoz, J.-C.; Retaux, S.; Casane, D.
10.1101/2021.12.13.472396 — evolutionary biology — Posted on 2021-12-14
2150 There and Back to the Present: An Evolutionary Tale on Biological Diversity
Duarte, L.; Nakamura, G.; Debastiani, V.; Maestri, R.; Ramos Pereira, M. J. V. d. C.; Cianciaruso, M.; Diniz-Filho, J. A. F.
10.1101/2021.12.11.472171 — ecology — Posted on 2021-12-14
2151 Regenerated crustacean limbs are precise replicas
Almazan, A.; Cevrim, C.; Musser, J. M.; Averof, M.; Paris, M.
10.1101/2021.12.13.472338 — developmental biology — Posted on 2021-12-14
2153 Neuroimaging signature associated with symptom exacerbation in early-stage psychosis
Mihaljevic, M.; Nagpal, A.; Etyemez, S.; Narita, Z.; Ross, A.; Schaub, R.; Cascella, N.; Nucifora, F. C.; Coughlin, J. M.; Nestadt, G.; Sedlak, T. W.; Calhoun, V.; Faria, A.; Yang, K.; Sawa, A.
10.1101/2021.12.10.472143 — neuroscience — Posted on 2021-12-14
2154 Impaired dynamics of prefrontal beta-band networks during cognitive action control in Parkinson's disease
Duprez, J.; Tabbal, J.; Hassan, M.; Modolo, J.; Kabbara, A.; Mheich, A.; Drapier, S.; Verin, M.; Sauleau, P.; Wendling, F.; Benquet, P.; Houvenaghel, J. F.
10.1101/2021.12.12.472263 — neuroscience — Posted on 2021-12-14
2156 Virtual reality-based sensorimotor adaptation shapes subsequent spontaneous and naturalistic stimulus-driven brain activity
Wilf, M.; Dupuis, C.; Nardo, D.; Huber, D.; Sander, S.; Al-Kaar, J.; Haroud, M.; Perrin, H.; Fornari, E.; Crottaz-Herbette, S.; Serino, A.
10.1101/2021.12.13.471903 — neuroscience — Posted on 2021-12-14
2158 Brain injury environment critically influences the connectivity of transplanted neurons
Grade, S.; Thomas, J.; Zarb, Y.; Thorwirth, M.; Conzelmann, K.-K.; Hauck, S. M.; Goetz, M.
10.1101/2021.12.13.472270 — neuroscience — Posted on 2021-12-14
2159 Brassica napus genes Rlm4 and Rlm7, conferring resistance to Leptosphaeria maculans, are alleles of the Rlm9 wall-associated kinase-like resistance locus
Haddadi, P.; Larkan, N. J.; Van de Wouw, A.; Zhang, Y.; Neik, T. X.; Beynon, E.; Bayer, P.; Edwards, D.; Batley, J.; Borhan, H.
10.1101/2021.12.11.471845 — plant biology — Posted on 2021-12-14
2160 Unexpected short- and long-term effects of chronic adolescent HU-210 exposure on emotional behavior
Farinha-Ferreira, M.; Rei, N.; Fonseca-Gomes, J.; Miranda-Lourenco, C.; Serrão, P.; Vaz, S. H.; Gomes, J. I.; Martins, V.; de Alves Pereira, B.; Sebastiao, A. M.
10.1101/2021.12.13.472275 — pharmacology and toxicology — Posted on 2021-12-14
2162 Molecular switch between mammalian MLL complexes dictates response to Menin-MLL inhibition
Soto-Feliciano, Y. M.; Sanchez-Rivera, F. J.; Perner, F.; Barrows, D. W.; Kastenhuber, E. R.; Ho, Y.-J.; Carroll, T.; Xiong, Y.; Anand, D.; Soshnev, A.; Gates, L.; Beytagh, M. C.; Cheon, D.; Gu, S.; Liu, X. S.; Krivtsov, A. V.; Meneses, M.; de Stanchina, E.; Stone, R. M.; Armstrong, S. A.; Lowe, S. W.; Allis, C. D.
10.1101/2021.10.22.465184 — cancer biology — Posted on 2021-12-14
2164 KRAS G12D can be targeted by potent salt-bridge forming inhibitors
Mao, Z.; Xiao, H.; Shen, P.; Yang, Y.; Xue, J.; Yang, Y.; Shang, Y.; Zhang, L.; Li, X.; Zhang, Y.; Du, Y.; Chen, C.-C.; Guo, R.-T.; Zhang, Y.
10.1101/2021.12.13.472365 — cancer biology — Posted on 2021-12-14
2165 Models for Evaluation of Biological Age Based on Multi-omics
Huang, C.; Zhu, Y.; Huo, F.; Feng, S.; Gong, X.; Jiang, H.; Liu, Z.; Liu, H.
10.1101/2021.12.13.472382 — genomics — Posted on 2021-12-14
2166 Metabolic reconstitution by a gnotobiotic microbiota varies over the circadian cycle
Hoces, D.; Lan, J.; Sun, W.; Geiser, T.; Cappio Barazzone, E.; Arnoldini, M.; Nowok, S.; Macpherson, A. J.; Stecher, B.; Zenobi, R.; Hardt, W.-D.; Wolfrum, C.; Slack, E.
10.1101/2021.09.08.456534 — microbiology — Posted on 2021-12-14
2167 Mathematical Relationships between Spinal Motoneuron Properties
Caillet, A. H. D.; Phillips, A. T. M.; Farina, D.; Modenese, L.
10.1101/2021.08.05.455188 — neuroscience — Posted on 2021-12-14
2168 Musicianship can be decoded from magnetic resonance images
Puoliväli, T.; Sipola, T.; Thiede, A.; Kliuchko, M.; Bogert, B.; Toiviainen, P.; Nandi, A. K.; Parkkonen, L.; Brattico, E.; Ristaniemi, T.; Parviainen, T.
10.1101/2020.07.19.210906 — neuroscience — Posted on 2021-12-14
2169 A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1
Closa, A.; Reixachs-Sole, M.; Fuentes-Fayos, A. C.; Hayer, K. E.; Melero, J. L.; Adriaanse, F. R.; Bos, R. S.; Torres-Diz, M.; Hunger, S.; Roberts, K. G.; Mullighan, C.; Stam, R. W.; Thomas-Tikhonenko, A.; Castano, J. P.; Luque, R. M.; Eyras, E.
10.1101/2021.12.13.472370 — cancer biology — Posted on 2021-12-14
2170 Somatic mutation rates scale with lifespan across mammals
Cagan, A.; Baez-Ortega, A.; Brzozowska, N.; Abascal, F.; Coorens, T. H. H.; Sanders, M. A.; Lawson, A. R. J.; Harvey, L. M. R.; Bhosle, S. G.; Jones, D.; Alcantara, R. E.; Butler, T. M.; Hooks, Y.; Roberts, K.; Anderson, E.; Flach, E.; Spiro, S.; Januszczak, I.; Wrigglesworth, E.; Perkins, M. W.; Deaville, R.; Druce, M.; Bogeska, R.; Milsom, M. D.; Neumann, B.; Gorman, F.; Constantino-Casas, F.; Peachey, L.; Bochynska, D.; Smith, E. S. J.; Gerstung, M.; Campbell, P. J.; Murchison, E. P.; Stratton, M. R.; Martincorena, I.
10.1101/2021.08.19.456982 — genomics — Posted on 2021-12-14
2171 Reprogrammed iBlastoids contain amnion-like cells but not trophectoderm
Zhao, C.; Plaza Reyes, A.; Schell, J. P.; Weltner, J.; Ortega, N.; Zheng, Y.; Bjorklund, A. K.; Rossant, J.; Fu, J.; Petropoulos, S.; Lanner, F.
10.1101/2021.05.07.442980 — developmental biology — Posted on 2021-12-14
2181 Gross anatomy of the gluteal and posterior thigh muscles in koalas based on their innervations
Tojima, S.; Anetai, H.; Koike, K.; Anetai, S.; Tokita, K.; Leigh, C.; Kumaratilake, J.
10.1101/2021.12.13.472422 — zoology — Posted on 2021-12-13
2185 Characterization of metabolic compartmentalization in the liver using spatially resolved metabolomics
van der Reest, J.; Stopka, S. A.; Abdelmoula, W. M.; Ruiz, D. F.; Joshi, S.; Ringel, A.; Haigis, M. C.; Agar, N. Y. R.
10.1101/2021.12.13.472421 — biochemistry — Posted on 2021-12-13
2192 The Carotid Body Detects Circulating Tumor Necrosis Factor-Alpha to Activate a Sympathetic Anti-Inflammatory Reflex
Katayama, P. L.; Leirao, I. d. P.; Kanashiro, A.; Luiz, J. P. M.; Cunha, F. Q.; Navegantes, L. C. C.; Menani, J. V.; Zoccal, D. B.; Colombari, D. S. d. A.; Colombari, E.
10.1101/2021.10.20.463417 — neuroscience — Posted on 2021-12-13
2194 Pose-gait analysis for cetaceans with biologging tags
Zhang, D.; Goodbar, K.; West, N.; Lesage, V.; Parks, S. E.; Wiley, D.; Barton, K.; Shorter, K. A.
10.1101/2021.12.13.472407 — animal behavior and cognition — Posted on 2021-12-13
2199 Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA
Lee, Y. H.; Jang, H.-J.; Kim, S.; Choi, S. S.; Khim, K. W.; Eom, H.-J.; Hyun, J.; Shin, K. J.; Chae, Y. C.; Kim, H.; Park, J.; Park, N. H.; Woo, C.-Y.; Hong, C. H.; Koh, E. H.; Nam, D.; Choi, J. h.
10.1101/2021.06.07.447348 — molecular biology — Posted on 2021-12-13
2200 Myocardial BDNF regulates cardiac bioenergetics through the transcription factor Yin Yang 1
Yang, X.; Zhang, M.; Xie, B.; Zimmerman, R. J.; Wang, Q.; Wei, A.-c.; Peng, Z.; Khalifa, M.; Reynolds, M.; Om, M.; Zhu, G.; Bedja, D.; Jiang, H.; Jurczak, M.; Shiva, S. S.; Scott, I.; O'Rourke, B.; Kass, D. A.; Paolocci, N.; Feng, N.
10.1101/2021.01.19.427213 — molecular biology — Posted on 2021-12-13
2201 A simple, cheap, and robust protocol for the identification of mating type in Saccharomyces cerevisiae
Arras, S. D. M.; Hibbard, T. R.; Mitsugi-McHattie, L.; Woods, M. A.; Johnson, C. E.; Munkacsi, A.; Hermann-Le Denmat, S.; Ganley, A. R. D.
10.1101/2020.01.19.911990 — microbiology — Posted on 2021-12-13
2202 An intestinally secreted host factor promotes microsporidia invasion of C. elegans
El Jarkass, H. T.; Mok, C.; Schertzberg, M. R.; Fraser, A. G.; Troemel, E. R.; Reinke, A. W.
10.1101/2021.07.12.452088 — microbiology — Posted on 2021-12-13
2203 Mice alternate between discrete strategies during perceptual decision-making
Ashwood, Z. C.; Roy, N. A.; Stone, I. R.; The International Brain Laboratory, ; Urai, A. E.; Churchland, A. K.; Pouget, A.; Pillow, J. W.
10.1101/2020.10.19.346353 — neuroscience — Posted on 2021-12-13
2204 A somatosensory computation that unifies limbs and tools
Miller, L.; Fabio, C.; de Vignemont, F.; Roy, A.; Medendorp, W. P.; Farne, A.
10.1101/2021.12.09.472009 — neuroscience — Posted on 2021-12-13
2205 Neural support for contributions of utility and narrative processing of evidence in juror decision making
Castrellon, J. J.; Hakimi, S.; Parelman, J. M.; Yin, L.; Law, J. R.; Skene, J. A. G.; Ball, D. A.; Malekpour, A.; Beskind, D. H.; Vidmar, N.; Pearson, J. M.; Carter, R. M.; Skene, J. H. P.
10.1101/2020.11.11.378935 — neuroscience — Posted on 2021-12-13
2206 Improving Lab Culture Through Self-Assessment: A Case Study
Hernandez, S.; Mumme, R.; Court, L.; El Basha, D.; Gay, S.; Marquez, B.; Xiao, Y.; Huang, K.; Baroudi, H.; Cao, W.; Cardenas, C.; Douglas, R.; Duryea, J.; Kaffey, Z.; Mann, D.; Nealon, K.; Netherton, T.; Nguyen, C.; Oh, K.; Olanrewaju, A.; Sjogreen, C.; Rhee, D. J.; Yang, J.; Yu, C.; Zhang, L. J.; Zhao, Y.; Ziyaee, H.; Gronberg, M.
10.1101/2021.12.08.471870 — scientific communication and education — Posted on 2021-12-13
2207 3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib
Meraz, I. M.; Majidi, M.; Fang, B.; Meng, F.; Gao, L.; Shao, R.; Song, R.; Li, F.; Ha, M. J.; Wang, Q.; Wang, J.; Shpall, E. J.; Jung, S. Y.; Haderk, F.; Gui, P.; Riess, J. W.; Olivas, V.; Bivona, T. G.; Roth, J. A.
10.1101/2021.12.10.472153 — cancer biology — Posted on 2021-12-13
2208 A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1
Adria, A.; Reixachs-Sole, M.; Fuentes-Fayos, A. C.; Hayer, K. E.; Melero, J. L.; Adriaanse, F. R.; Bos, R. S.; Torres-Diz, M.; Hunger, S.; Roberts, K. G.; Mullighan, C.; Stam, R. W.; Thomas-Tikhonenko, A.; Castaño, J. P.; Luque, R. M.; Eyras, E.
10.1101/2021.12.13.472370 — cancer biology — Posted on 2021-12-13
2209 WESTPA 2.0: High-performance upgrades for weighted ensemble simulations and analysis of longer-timescale applications
Russo, J.; Zhang, S.; Leung, J.; Bogetti, A.; Thompson, J.; DeGrave, A.; Torrillo, P.; Pratt, A. J.; Wong, K.; Xia, J.; Copperman, J. T.; Adelman, J.; Zwier, M.; LeBard, D.; Zuckerman, D. M.; Chong, L.
10.1101/2021.12.05.471280 — biophysics — Posted on 2021-12-13
2212 BIONIC: Biological Network Integration using Convolutions
Forster, D. T.; Li, S. C.; Yashiroda, Y.; Yoshimura, M.; Li, Z.; Isuhuaylas, L. A. V.; Itto-Nakama, K.; Yamanaka, D.; Ohya, Y.; Osada, H.; Wang, B.; Bader, G.; Boone, C.
10.1101/2021.03.15.435515 — bioinformatics — Posted on 2021-12-13
2216 Nutrient metabolism regulates insulin granule formation in the pancreatic islet β-cell via ER redox homeostasis
Rohli, K. E.; Boyer, C. K.; Bearrows, S. C.; Moyer, M. R.; Elison, W. S.; Bauchle, C. J.; Blom, S. E.; Yu, C.-L.; Pope, M. R.; Zhang, J.; Wang, Y.; Stephens, S. B.
10.1101/2021.09.22.461417 — cell biology — Posted on 2021-12-13
2217 SMER28 attenuates PI3K/mTOR signaling by direct inhibition of PI3K p110 delta
Kirchenwitz, M.; Stahnke, S.; Prettin, S.; Borowiak, M.; Birchmeier, C.; Rottner, K.; Stradal, T. E. B.; Steffen, A.
10.1101/2021.12.10.471916 — cell biology — Posted on 2021-12-13
2218 Experimental evolution to identify undescribed mechanisms of resistance to a novel cationic peptide antibiotic
Santos Lopez, A.; Fritz, M. J.; Lombardo, J.; Burr, A. H.; Heinrich, V. A.; Marshall, C. W.; Cooper, V. S.
10.1101/2020.12.16.423161 — microbiology — Posted on 2021-12-13
2220 The TRPV Channel OSM-9 is Required for Sleep-Dependent Olfactory Memory and is Expressed in Sensory Neurons That Do Not Promote Butanone Attraction
Benedetti, K. L.; Miller, J. M.; Saifuddin, F. A.; Chandra, R.; Chen, A.; Lin, C.; Borchardt, J.; Daigle, K. D. C.; Dunn, R. L.; Kaye, J. A.; Zhang, B.; Kato, S.; Gallegos, M. E.; Wittmann, T.; L'Etoile, N.
10.1101/2020.11.27.400747 — neuroscience — Posted on 2021-12-13
2222 Applications of AlphaFold beyond Protein Structure Prediction
Zhang, Y.; Li, P.; PAN, F.; Liu, H.; Hong, P.; Liu, X.; Zhang, J.
10.1101/2021.11.03.467194 — bioinformatics — Posted on 2021-12-13
2223 Progressive alterations of striatal polysomal architecture in a mouse model of Huntington's disease
Martin-Solana, E.; Diaz-Lopez, I.; Ventoso, I.; Fernandez, J.-J.; Fernandez-Fernandez, M. R.
10.1101/2021.12.13.472357 — neuroscience — Posted on 2021-12-13
2225 Endoplasmic reticulum oxidoreductin (ERO) provides resilience against reductive stress and hypoxic conditions by mediating luminal redox dynamics
Ugalde, J. M.; Aller, I.; Kudrjasova, L.; Schmidt, R.; Schloesser, M.; Homagk, M.; Fuchs, P.; Lichtenauer, S.; Schwarzlaender, M.; Mueller-Schuessele, S.; Meyer, A.
10.1101/2021.12.13.472397 — plant biology — Posted on 2021-12-13
2226 Mitochondrial Dysfunction is a Driver for SP-2509 Drug Resistance in Ewing Sarcoma
Tokarsky, E. J. P.; Crow, J. C.; Guenther, L. M.; Sherman, J.; Taslim, C.; Alexe, G.; Pishas, K. I.; Rask, G.; Justis, B. S.; Kasumova, A.; Stegmaier, K.; Lessnick, S. L.; Theisen, E. R.
10.1101/2021.12.13.472459 — cancer biology — Posted on 2021-12-13
2228 A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1
Adria, A.; Reixachs-Sole, M.; Fuentes-Fayos, A. C.; Hayer, K. E.; Melero, J. L.; Adriaanse, F. R.; Bos, R. S.; Torres-Diz, M.; Hunger, S.; Roberts, K. G.; Mullighan, C.; Stam, R. W.; Thomas-Tikhonenko, A.; Castaño, J. P.; Luque, R. M.; Eyras, E.
10.1101/2021.12.13.472370 — cancer biology — Posted on 2021-12-13
2230 Modelling biochemical gradients in vitro to control cell compartmentalization in a microengineered 3D model of the intestinal epithelium
Altay, G.; Abad-Lazaro, A.; Gualda, E. J.; Folch, J.; Insa, C.; Tosi, S.; Hernando-Momblona, X.; Batlle, E.; Loza, P.; Fernandez-Majada, V.; Martinez, E.
10.1101/2021.12.13.472418 — bioengineering — Posted on 2021-12-13
2231 The anti-angiogenic compound dimethyl fumarate inhibits the serine synthesis pathway and increases glycolysis in endothelial cells
Ocana, M. C.; Yang, C.; Bernal, M.; Martinez-Poveda, B.; Vu, H. S.; Cardenas, C.; DeBerardinis, R. J.; Quesada, A. R.; Medina, M. A.
10.1101/2021.12.13.472337 — biochemistry — Posted on 2021-12-13
2233 Lessons from the meiotic recombination landscape of the ZMM deficient budding yeast Lachancea waltii
Dutreux, F.; Dutta, A.; Peltier, E.; Bibi-Triki, S.; Friedrich, A.; llorente, b.; Schacherer, J.
10.1101/2021.12.13.472358 — genetics — Posted on 2021-12-13
2237 Oxoglutarate dehydrogenase coordinates myofibril growth by maintaining amino acid homeostasis
Morales, N. G.; Marescal, O.; Szikora, S.; Erdelyi, M.; Biro, P.; Mesquita, T.; Mihaly, J.; Schöck, F.
10.1101/2021.12.13.472149 — cell biology — Posted on 2021-12-13
2238 A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
Gorbunova, V.; Simon, M.; Trombline, G.; Yang, J.; Earley, E. J.; Zhang, L.; Gigas, J.; Zagorulya, M.; Gilbert, M.; Robbins, P. D.; Vijg, J.; Seluanov, A.; Suh, Y.; Garcia, B.; Thomas, D. D.; Yuen, S. L.; Pope, A.; Van Meter, M.; Emmrich, S.; Moody, K.; Barzilai, N.; Wolfe, A.; Atzmon, G.; Schaff, T. M.
10.1101/2021.12.13.472381 — molecular biology — Posted on 2021-12-13
2240 Adenine Base Editing in vivo with a Single Adeno-Associated Virus Vector
Zhang, H.; Bamidele, N.; Liu, P.; Ojelabi, O.; Gao, X. D.; Rodriguez, T.; Cheng, H.; Wolfe, S. A.; Xue, W.; Sontheimer, E. J.
10.1101/2021.12.13.472434 — molecular biology — Posted on 2021-12-13
2241 Adeno-associated virus type 2 (AAV2) uncoating is a stepwise process and is linked to structural reorganization of the nucleolus
Sutter, S. O.; Lkharrazi, A.; Schraner, E. M.; Michaelsen, K.; Meier, A. F.; Vogt, B.; Büning, H.; Fraefel, C.
10.1101/2021.12.13.472349 — molecular biology — Posted on 2021-12-13
2242 An mRNA silencing mechanism reliant on the cooperation between REGE-1/Regnase-1 and RLE-1/Roquin-1
Sobanska, D.; Komur, A. A.; Chabowska-Kita, A.; Gumna, J.; Kumari, P.; Pachulska-Wieczorek, K.; Ciosk, R.
10.1101/2021.12.13.472375 — molecular biology — Posted on 2021-12-13
2243 Broad antiviral effects of Echinacea purpurea against SARS-CoV-2 variants of concern and potential mechanism of action
Vimalanathan, S.; Shehata, M.; Sadasivam, K.; Delbue, S.; Dolci, M.; Pariani, E.; D'Alessandro, S.; Pleschka, S.
10.1101/2021.12.12.472255 — microbiology — Posted on 2021-12-13
2246 An amphipathic and cationic antimicrobial peptide kills colistin resistant Gram-negative pathogens in vivo
Thomsen, T. T.; Kolpen, M.; Wigneswaran, V.; Kromann, U.; Ebbensgaard, A.; Hammerum, A. M.; Hasman, H.; Radmer, S.; Kragh, K. N.; Hartmann-Petersen, R.; Hansen, P. R.; Folkesson, A.; Frimodt-Moller, N.; Lobner-Olesen, A.
10.1101/2021.12.13.472350 — microbiology — Posted on 2021-12-13
2248 Molecular Epidemiology and Microbiological Characteristics of Cryptococcus gattii VGII isolates from China
zang, x.; ke, w.; wang, l.; wu, h.; huang, y.; deng, h.; zhou, m.; wu, n.; shen, d.; xue, x.
10.1101/2021.12.13.472347 — microbiology — Posted on 2021-12-13
2251 Yield is negatively correlated with nucleotide-binding leucine-rich repeat gene content in soybean
Bayer, P. E.; Hu, H.; Petereit, J.; Varshney, R. K.; Valliyodan, B.; Nguyen, H. T.; Batley, J.; Edwards, D.
10.1101/2021.12.12.472330 — plant biology — Posted on 2021-12-13
2252 Single-molecule sizing through nano-cavity confinement
Jacquat, R. P. B.; Krainer, G.; Peter, Q.; Babar, A. N.; Vanderpoorten, O.; Xu, C. K.; Kaminski, C. F.; Keyser, U. F.; Baumberg, J. J.; Knowles, T. P. J.
10.1101/2021.12.13.472369 — biophysics — Posted on 2021-12-13
2256 Age dependent changes in circulating Tfh cells influence the development of functional antibodies to malaria in children.
Chan, J.-A.; Loughland, J.; de la Parte, L.; Okano, S.; Ssewanyana, I.; Nalubega, M.; Nankya, F.; Musinguzi, K.; Rek, J.; Arinaitwe, E.; Tipping, P.; Bourke, P.; Andrew, D.; Dooley, N.; SheelaNair, A.; Wines, B. D.; Hogarth, M.; Beeson, J.; Greenhouse, B.; Dorsey, G.; Kamya, M.; Hartel, G.; Minigo, G.; Feeney, M.; Jagannathan, P.; Boyle, M. J.
10.1101/2021.12.12.472299 — immunology — Posted on 2021-12-13
2257 In vitro validation of neoantigen prediction algorithm for developing personalized cancer vaccine therapy
Choe, Y.-j.; Kim, E.; Oh, J.; Jang, M.; Fu, W.; Lee, H.; Jung, M.; Pyo, K.-H.; Synn, C.-B.; Kim, S.; Yang, Y.; Kim, A.; Cho, B. C.; Kim, H. S.; Kim, S.; Carreno, B.; Kim, J. Y.; Paik, S.
10.1101/2021.12.12.472304 — immunology — Posted on 2021-12-13
2259 Dynamics of CTCF and cohesin mediated chromatin looping revealed by live-cell imaging
Gabriele, M.; Brandao, H. B.; Grosse-Holz, S.; Jha, A.; Dailey, G. M.; Cattoglio, C.; Hsieh, T.-H. S.; Mirny, L.; Zechner, C.; Hansen, A. S.
10.1101/2021.12.12.472242 — biophysics — Posted on 2021-12-13
2260 The Prion Protein Octarepeat Domain Forms Transient β-sheet Structures Upon Residue-Specific Cu(II) and Zn(II) Binding
Gielnik, M.; Szymanska, A.; Dong, X.; Jarvet, J.; Svedruzic, Z. M.; Graslund, A.; Kozak, M.; Warmlander, S. K. T. S.
10.1101/2021.12.12.472308 — biophysics — Posted on 2021-12-13
2264 Stressed out underground?: Transcriptomics illuminates the genome-wide response to heat stress in surface and subterranean diving beetles
Beasley-Hall, P. G.; Bertozzi, T.; Bradford, T. M.; Foster, C. S. P.; Jones, K.; Tierney, S. M.; Humphreys, W. F.; Austin, A. D.; Cooper, S. J. B.
10.1101/2021.12.12.470823 — evolutionary biology — Posted on 2021-12-13
2265 Microbial associations with Microscopic Colitis
Sun, S.; Blakley, I.; Fodor, A. A.; Keku, T. O.; Woosley, J. T.; Peery, A. F.; Sandler, R. S.
10.1101/2021.12.10.472154 — microbiology — Posted on 2021-12-13
2266 Acyl-CoA Thioesterases; a rheostat that controls activated fatty acids modulates dengue virus serotype 2 replication
St Clair, L. A.; Mills, S. A.; Lian, E.; Soma, P. S.; Nag, A.; Montgomery, C.; Ramirez, G.; Chotiwan, N.; Gullberg, R. C.; Perera, R.
10.1101/2021.12.12.472314 — microbiology — Posted on 2021-12-13
2269 Localized, time-dependent responses of rat cranial bone to repeated mild traumatic brain injuries
Dill, L. K.; Sims, N. A.; Shad, A.; Anyaegbu, C.; Warnock, A.; Mao, Y.; Fitzgerald, M.; Semple, B. D.
10.1101/2021.12.12.472300 — neuroscience — Posted on 2021-12-13
2270 Acoustic camera system for measuring ultrasound communication in mice
Matsumoto, J.; Kanno, K.; Kato, M.; Nishimaru, H.; Setogawa, T.; Chinzorig, C.; Shibata, T.; Nishijo, H.
10.1101/2021.12.12.468927 — neuroscience — Posted on 2021-12-13
2272 EraSOR: Erase Sample Overlap in polygenic score analyses
Choi, S. W.; Mak, T. S. H.; Hoggart, C. J.; O'Reilly, P. F.
10.1101/2021.12.10.472164 — bioinformatics — Posted on 2021-12-13
2273 Personalized models of breast cancer desmoplasia reveal biomechanical determinants of drug penetration
Offeddu, G. S.; Haase, K.; Wan, Z.; Possenti, L.; Nguyen, H. T.; Gillrie, M. R.; Hickman, D.; Knutson, C. G.; Kamm, R. D.
10.1101/2021.12.12.472296 — bioengineering — Posted on 2021-12-13
2277 Evidence for alternate stable states in an Ecuadorian Andean Cloud Forest
Mariscal Chavez, A.; Thomas, D. C.; Haffenden, A.; Manobanda, R.; Duvauchelle, L.; Defas, W.; Angel Chinchero, M.; Simba Larco, J. D.; Jaramillo, E.; Roy, B. A.; Peck, M.
10.1101/2021.11.26.470126 — ecology — Posted on 2021-12-13
2278 Following the track: accuracy and reproducibility of predation assessment on artificial caterpillars
Valdes-Correcher, E.; Mantyla, E.; Barbaro, L.; Damestoy, T.; Sam, K.; Castagneyrol, B.
10.1101/2021.12.10.472105 — ecology — Posted on 2021-12-13
2280 Improved neutralization of the SARS-CoV-2 Omicron variant after Pfizer-BioNTech BNT162b2 COVID-19 vaccine boosting
Basile, K.; Rockett, R. J.; McPhie, K.; Fennell, M.; Johnson-Mackinnon, J.; Agius, J.; Fong, W.; Rahman, H.; Ko, D.; Donavan, L.; Hueston, L.; Lam, C.; Arnott, A.; Chen, S.; Maddocks, S.; O'Sullivan, M.; Dwyer, D. E.; Sintchenko, V.; Kok, J.
10.1101/2021.12.12.472252 — microbiology — Posted on 2021-12-13
2281 SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling
Biering, S. B.; Tramontini Gomes de Sousa, F.; Tjang, L. V.; Pahmeier, F.; Ruan, R.; Blanc, S. F.; Patel, T. S.; Worthington, C. M.; Glasner, D. R.; Castillo-Rojas, B.; Servellita, V.; Lo, N. T.; Wong, M. P.; Warnes, C. M.; Sandoval, D. R.; Clausen, T. M.; Santos, Y. A.; Ortega, V.; Aguilar-Carreno, H.; Esko, J. D.; Chiu, C. Y.; Pak, J. E.; Beatty, P. R.; Harris, E.
10.1101/2021.12.10.472112 — microbiology — Posted on 2021-12-13
2282 SARS-CoV2 variant-specific replicating RNA vaccines protect from disease and pathology and reduce viral shedding following challenge with heterologous SARS-CoV2 variants of concern
Hawman, D. W.; Meade-White, K.; Archer, J.; Leventhal, S.; Wilson, D.; Shaia, C.; Randall, S.; Khandhar, A. P.; Hsiang, T.-Y.; Gale, M.; Berglund, P.; Fuller, D. H.; Feldmann, H.; Erasmus, J.
10.1101/2021.12.10.472134 — microbiology — Posted on 2021-12-13
2285 Antimicrobial resistance determinants in silage
Nagy, S. A.; Toth, A. G.; Papp, M.; Kaplan, S.; Solymosi, N.
10.1101/2021.12.12.472282 — genomics — Posted on 2021-12-13
2289 The Omicron variant is highly resistant against antibody-mediated neutralization - implications for control of the COVID-19 pandemic
Hoffmann, M.; Krüger, N.; Schulz, S.; Cossmann, A.; Rocha, C.; Kempf, A.; Nehlmeier, I.; Graichen, L.; Moldenhauer, A.-S.; Winkler, M. S.; Lier, M.; Dopfer-Jablonka, A.; Jäck, H.-M.; Behrens, G.; Pöhlmann, S.
10.1101/2021.12.12.472286 — microbiology — Posted on 2021-12-13
2294 Spatial organization of nuclear pores in Xenopus laevis oocytes
Ravazzano, L.; Bonfanti, S.; Guerra, R.; Montel, F.; La Porta, C. A. M.; Zapperi, S.
10.1101/2021.09.01.458492 — biophysics — Posted on 2021-12-13
2298 From COVID-19 to the Common Cold: Novel Host-Targeted, Pan-Respiratory Antiviral Small Molecule Therapeutics
Selvarajah, S.; Lingappa, A. F.; Michon, M.; Du, L.; Deiter, F.; Yu, S. F.; Macieik, A.; Mallesh, S.; Appiah, U.; Crabtree, J.; Copeland, K.; Mueller-Schiffmann, A.; Mueller, L.; Ostermann, P. N.; Andree, M.; Adams, O.; Schaal, H.; Hogan, R. J.; Tripp, R. A.; Anand, S. K.; Campi, T. W.; Ford, M. J.; Reed, J. C.; Lin, J.; Akintunde, O.; Nichols, C.; Petrouski, E.; Moreira, A. R.; Jiang, I.-t.; DeYarman, N.; Broce, S.; Brown, I.; Segal, I.; Goldsmith, D.; Lau, S.; Hong, S.; Asundi, V.; Briggs, E. M.; Phyo, N. S.; Froehlich, M.; Onisko, B.; Matlack, K.; Dey, D.; Lingappa, J. R.; Prasad, M. D.; Ko
10.1101/2021.01.17.426875 — biochemistry — Posted on 2021-12-13
2299 Cell transcriptomic atlas of the non-human primate Macaca fascicularis
Han, L.; Wei, X.; Liu, C.; Volpe, G.; Zhuang, Z.; Zou, X.; Wang, Z.; Pan, T.; Yuan, Y.; Zhang, X.; Fan, P.; Guo, P.; Lai, Y.; Lei, Y.; Liu, X.; Yu, F.; Shangguan, S.; Lai, G.; Deng, Q.; Liu, Y.; Wu, L.; Shi, Q.; Yu, H.; Huang, Y.; Cheng, M.; Xu, J.; Liu, Y.; Wang, M.; Wang, C.; Zhang, Y.; Xie, D.; Yang, Y.; Yu, Y.; Zheng, H.; Wei, Y.; Huang, F.; Lei, J.; Huang, W.; Zhu, Z.; Lu, H.; Wang, B.; Wei, X.; Chen, F.; Yang, T.; Du, W.; Chen, J.; Xu, S.; An, J.; Ward, C.; Wang, Z.; Pei, Z.; Wong, C.-W.; Liu, X.; Zhang, H.; Liu, M.; Qin, B.; Schambach, A.; Isern, J.; Feng, L.; Liu, Y.; Guo, X.; Liu, Z.;
10.1101/2021.12.13.472311 — cell biology — Posted on 2021-12-13
2300 Delta breakthrough infections elicit potent, broad and durable neutralizing antibody responses
Walls, A. C.; Sprouse, K. R.; Joshi, A.; Bowen, J. E.; Franko, N.; Navarro, M.-J.; Stewart, C.; McCallum, M.; Goecker, E. A.; Degli-Angeli, E. J.; Logue, J.; Greninger, A.; Chu, H.; Veesler, D.
10.1101/2021.12.08.471707 — immunology — Posted on 2021-12-13
2302 Transcriptional and Cytotoxic Responses of Human Intestinal Organoids to Interferon Types I, II, and III
Constant, D. A.; Van Winkle, J. A.; VanderHoek, E.; Dekker, S. E.; Sofia, M. A.; Regner, E.; Tsikitis, V. L.; Modiano, N.; Nice, T. J.
10.1101/2021.12.11.472223 — immunology — Posted on 2021-12-13
2306 Electrically Controlling and Optically Observing the Membrane Potential of Supported Lipid Bilayers
Yudovich, S.; Marzouqe, A.; Kantorovitsch, J.; Teblum, E.; Chen, T.; Enderlein, J.; Miller, E. W.; Weiss, S.
10.1101/2021.12.10.472087 — biophysics — Posted on 2021-12-13
2307 Present and future distribution of bat hosts of sarbecoviruses: implications for conservation and public health
Muylaert, R. L.; Kingston, T.; Luo, J.; Vancine, M. H.; Galli, N.; Carlson, C.; John, R. S.; Rulli, M. C.; Hayman, D. T. S.
10.1101/2021.12.09.471691 — ecology — Posted on 2021-12-13
2310 Peptide Aggregation Induced Immunogenic Rupture (PAIIR)
Gunay, G.; Hamsici, S.; Acar, H.; Lang, M. L.; Lang, G. A.; Kovats, S.
10.1101/2021.12.11.472230 — bioengineering — Posted on 2021-12-13
2312 Buffering of transcription rate by mRNA half-life is a conserved feature of Rett syndrome models
Rodrigues, D. C.; Mufteev, M.; Yuki, K. E.; Narula, A.; Wei, W.; Piekna, A.; Liu, J.; Pasceri, P.; Rissland, O. S.; Wilson, M. D.; Ellis, J.
10.1101/2021.12.11.472181 — neuroscience — Posted on 2021-12-13
2313 Comparative analysis of gene prediction tools for viral genome annotation
Gonzalez-Tortuero, E.; Krishnamurthi, R.; Allison, H. E.; Goodhead, I. B.; James, C. E.
10.1101/2021.12.11.472104 — bioinformatics — Posted on 2021-12-13
2314 Video-Based Deep Learning to Detect Dyssynergic Defecation with 3D High-Definition Anorectal Manometry
Levy, J.; Navas, C. M.; Chandra, J. A.; Christensen, B.; Vaickus, L. J.; Curley, M. A.; Chey, W. D.; Baker, J. R.; Shah, E. D.
10.1101/2021.12.11.472233 — bioinformatics — Posted on 2021-12-13
2318 Human and wildlife use of mountain glacier habitat in western North America
Hotaling, S.; Boersma, J.; Paprocki, N. A.; Anderson, A.; Whiles, L.; Ogburn, L.; Kasper, S.; White, C.; Thornton, D. H.; Wimberger, P.
10.1101/2021.12.10.472172 — ecology — Posted on 2021-12-13
2320 A somatosensory computation that unifies bodies and tools
Miller, L.; Fabio, C.; de Vignemont, F.; Roy, A.; Medendorp, W. P.; Farne, A.
10.1101/2021.12.09.472009 — neuroscience — Posted on 2021-12-13
2322 Passive inertial damping improves high-speed gaze stabilization in hoverflies
Hardcastle, B. J.; Bierig, K.; Heras, F. J.; Schwyn, D. A.; Longden, K. D.; Krapp, H. G.
10.1101/2021.12.11.472180 — neuroscience — Posted on 2021-12-13
2324 Evaluating denoising strategies in resting-state fMRI in traumatic brain injury (EpiBioS4Rx)
Weiler, M.; Casseb, R. F.; de Campos, B. M.; Crone, J. S.; Lutkenhoff, E. S.; Monti, M. M.; Vespa, P. M.
10.1101/2021.12.10.472139 — neuroscience — Posted on 2021-12-13
2327 robustica: customizable robust independent component analysis
Anglada-Girotto, M.; Miravet-Verde, S.; Serrano, L.; Head, S. A.
10.1101/2021.12.10.471891 — systems biology — Posted on 2021-12-13
2332 A Transcriptomic and Proteomic Atlas of Obesity and Type 2 Diabetes in Cynomolgus Monkeys
Zhang, X.; Lei, Y.; Homann, O.; Stolina, M.; Wang, S.; Veniant, M. M.; Hu, L. G.; Hsu, Y.-H.
10.1101/2021.12.10.472179 — genetics — Posted on 2021-12-13
2336 The economic burden of protecting islands from invasive alien species
Bodey, T.; Angulo, E.; Bang, A.; Bellard, C.; Fantle-Lepczyk, J.; Lenzner, B.; Turbelin, A.; Watari, Y.; Courchamp, F.
10.1101/2021.12.10.471372 — ecology — Posted on 2021-12-13
2338 Ebselen attenuates mycobacterial virulence through inhibition of ESX-1 secretion
Osman, M. M.; Pinckert, M. L.; Peak-Chew, S.; Troll, M. A.; Conrad, W. H.; Ramakrishnan, L.
10.1101/828574 — microbiology — Posted on 2021-12-13
2339 Predicting proprioceptive cortical anatomy and neural coding with topographic autoencoders
Blum, K. P.; Grogan, M. D.; Wu, Y.; Harston, A. J.; Miller, L. E.; Faisal, A. A.
10.1101/2021.12.10.472161 — neuroscience — Posted on 2021-12-13
2342 21/2-minute 3D 7T 31P-MRSI of the human heart using concentric rings (CRT)
Clarke, W. T.; Hingerl, L.; Strasser, B.; Bogner, W.; Valkovic, L.; Rodgers, C. T.
10.1101/2021.12.10.472120 — physiology — Posted on 2021-12-13
2343 Clonal hematopoiesis is driven by aberrant activation of TCL1A
Weinstock, J. S.; Gopakumar, J.; Burugula, B. B.; Uddin, M. M.; Jahn, N.; Belk, J. A.; Daniel, B.; Ly, N.; Mack, T. M.; Laurie, C. A.; Broome, J. G.; Taylor, K. D.; Guo, X.; Sinner, M. F.; von Falkenhausen, A. S.; Kaab, S.; Shuldiner, A. R.; O'Connell, J. R.; Lewis, J. P.; Boerwinkle, E.; Barnes, K. C.; Chami, N.; Kenny, E. E.; Loos, R. J. F.; Fornage, M.; Hou, L.; Lloyd-Jones, D. M.; Redline, S.; Cade, B. E.; Psaty, B. M.; Bis, J. C.; Brody, J. A.; Silverman, E. K.; Yun, J. H.; Qiao, D.; Palmer, N. D.; Freedman, B. I.; Bowden, D. W.; Cho, M. H.; DeMeo, D. L.; Vasan, R. S.; Johnson, A. D.; Mat
10.1101/2021.12.10.471810 — genetics — Posted on 2021-12-13
2344 Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance.
Chakravarthy, A.; Reddin, I.; Henderson, S.; Dong, C.; Kirkwood, N.; Jeyakumar, M.; Rothschild Rodriguez, D.; Gonzalez Martinez, N.; McDermott, J.; Su, X.; Egawa, N.; Fjeldbo, C. S.; Skingen, V. E.; Halle, M. K.; Krakstad, C.; Soleiman, A.; Sprung, S.; Ellis, P.; Wass, M.; Michaelis, M.; Lyng, H.; Fiegl, H.; Salvesen, H.; Thomas, G.; Doorbar, J.; Chester, K.; Feber, A.; Fenton, T. R.
10.1101/2020.04.02.019711 — cancer biology — Posted on 2021-12-13
2346 A zebrafish reporter line reveals immune and neuronal expression of endogenous retrovirus.
Rutherford, H. A.; Clarke, A.; Chambers, E. V.; Petts, J. J.; Carson, E. G.; Isles, H.; Duque-Jaramillo, A.; Renshaw, S. A.; Levraud, J.-P.; Hamilton, N.
10.1101/2021.01.21.427598 — cell biology — Posted on 2021-12-13
2349 Active antithrombin glycoforms are selectively physiosorbed on plasma extracellular vesicles
Radeghieri, A.; Alacqua, S.; Zendrini, A.; Previcini, V.; Todaro, F.; Martini, G.; Ricotta, D.; Bergese, P.
10.1101/2021.07.16.452649 — biochemistry — Posted on 2021-12-13
2351 Oscillatory movement of a dynein-microtubule complex crosslinked with DNA origami
Abdellatef, S. A.; Tadakuma, H.; Yan, K.; Fujiwara, T.; Fukumoto, K.; Kondo, Y.; Takazaki, H.; Boudria, R.; Yasunaga, T.; Higuchi, H.; Hirose, K.
10.1101/2021.12.06.471346 — biophysics — Posted on 2021-12-13
2353 Coordinated multiplexing of information about separate objects in visual cortex
Jun, N. Y.; Ruff, D. A.; Kramer, L. E.; Bowes, B.; Tokdar, S. T.; Cohen, M. R.; Groh, J. M.
10.1101/777912 — neuroscience — Posted on 2021-12-13
2354 Transmit Field Bias Correction of T1w/T2w Myelin Maps
Glasser, M. F.; Coalson, T. S.; Harms, M. P.; Baum, G. L.; Autio, J. A.; Auerbach, E. A.; Xu, J.; Greve, D. N.; Yacoub, E.; Van Essen, D. C.; Bock, N. A.; Hayashi, T.
10.1101/2021.08.08.455570 — neuroscience — Posted on 2021-12-13
2357 Multiple routes of functional diversification of the plant BAHD acyltransferase family revealed by comparative biochemical and genomic analyses
Kruse, L. H.; Weigle, A. T.; Irfan, M.; Martinez-Gomez, J.; Chobirko, J. D.; Schaffer, J. E.; Bennett, A. A.; Specht, C. D.; Jez, J. M.; Shukla, D.; Moghe, G. D.
10.1101/2020.11.18.385815 — plant biology — Posted on 2021-12-13
2358 Isolation and characterization of fucosylated extracellular vesicles based on a novel GlyExo-Capture technique
Li, B.; Hao, K.; Li, Z.; Ma, C.; Li, H.; Du, W.; Sun, L.; Jia, T.; Liu, A.; Li, Y.; Xu, L.; Gao, Q.; Yang, R.; Lin, C.
10.1101/2021.12.09.471505 — cancer biology — Posted on 2021-12-13
2359 Cryo-ET of HIV reveals Env positioning on Gag lattice and structural variation among Env trimers
Mangala Prasad, V.; Leaman, D. P.; Lovendahl, K. N.; Croft, J. T.; Benhaim, M. A.; Hodge, E. A.; Zwick, M. B.; Lee, K. K.
10.1101/2021.08.31.458345 — biophysics — Posted on 2021-12-13
2360 Microbiome-based disease prediction with multimodal variational information bottlenecks
Grazioli, F.; Siarheyeu, R.; Alqassem, I.; Henschel, A.; Pileggi, G.; Meiser, A.
10.1101/2021.06.08.447505 — bioinformatics — Posted on 2021-12-13
2362 Population inter-connectivity over the past 120,000 years explains distribution and diversity of Central African hunter-gatherers
Padilla-Iglesias, C.; Atmore, L.; Olivero, J.; Lupo, K.; Manica, A.; Arango Isaza, E.; Vinicius, L.; Migliano, A.
10.1101/2021.06.21.449204 — evolutionary biology — Posted on 2021-12-13
2370 Sensitizing solid tumors to CAR-mediated cytotoxicity using synthetic antigens
Gamboa, L.; Zamat, A. H.; Vanover, D.; Thiveaud, C. A.; Peck, H. E.; Phuengkham, H.; Sivakumar, A.; Harris, A. M.; Dahotre, S. N.; Su, F.-Y.; Santangelo, P. J.; Kwong, G. A.
10.1101/2021.12.11.472238 — bioengineering — Posted on 2021-12-12
2373 IGF1 Receptor Regulates Upward Firing Rate Homeostasis via the Mitochondrial Calcium Uniporter
Katsenelson, M.; Shapira, I.; Abbas, E.; Styr, B.; Aid, S.; Holzenberger, M.; Rizzoli, S.; Slutsky, I.
10.1101/2021.12.11.469196 — neuroscience — Posted on 2021-12-12
2376 Translation rescue by targeting Ppp1r15a upstream open reading frame in vivo
Kidwell, A.; Yadav, S. P. S.; Maier, B.; Zollman, A.; Ni, K.; Halim, A.; Janosevic, D.; Myslinski, J.; Syed, F.; Zeng, L.; Bopda Waffo, A.; Banno, K.; Xuei, X.; Doud, E. H.; Dagher, P. C.; Hato, T.
10.1101/2021.12.11.472232 — physiology — Posted on 2021-12-12
2378 Prolonged XPO1 inhibition is essential for optimal anti-leukemic activity in NPM1-mutated AML
Pianigiani, G.; Gagliardi, A.; Mezzasoma, F.; Rocchio, F.; Tini, V.; Bigerna, B.; Sportoletti, P.; Caruso, S.; Marra, A.; Spinozzi, G.; Shacham, S.; Landesman, Y.; Quintarelli, C.; Locatelli, F.; Martelli, M. P.; Falini, B.; Brunetti, L.
10.1101/2021.12.11.472216 — cancer biology — Posted on 2021-12-12
2380 Tabula Microcebus: A transcriptomic cell atlas of mouse lemur, an emerging primate model organism
The Tabula Microcebus Consortium, ; Ezran, C.; Liu, S.; Chang, S.; Ming, J.; Botvinnik, O.; Penland, L.; Tarashansky, A.; de Morree, A.; Travaglini, K. J.; Hasegawa, K.; Sin, H.; Sit, R.; Okamoto, J.; Sinha, R.; Zhang, Y.; Karanewsky, C. J.; Pendleton, J. L.; Morri, M.; Perret, M.; Aujard, F.; Stryer, L.; Artandi, S.; Fuller, M.; Weissman, I. L.; Rando, T. A.; Ferrell, J. E.; Wang, B.; De Vlaminck, I.; Yang, C.; Casey, K. M.; Albertelli, M. A.; Pisco, A. O.; Karkanias, J.; Neff, N.; Wu, A.; Quake, S. R.; Krasnow, M. A.
10.1101/2021.12.12.469460 — genetics — Posted on 2021-12-12
2381 Extreme drought triggers transition to an alternative soil microbial state
Cordero, I.; Leizeaga, A.; Hicks, L. C.; Rousk, J.; Bardgett, R. D.
10.1101/2021.12.10.472086 — ecology — Posted on 2021-12-12
2383 Glycine targets NINJ1-mediated plasma membrane rupture to provide cytoprotection
Borges, J. P.; Volchuk, A.; Kilburn, B.; Goldenberg, N. M.; Steinberg, B. E.
10.1101/2021.12.12.471765 — cell biology — Posted on 2021-12-12
2384 Regulation of mitochondrial proteostasis by the proton gradient
Patron, M.; Tarasenko, D.; Nolte, H.; Ghosh, M.; Ohba, Y.; Lasarzewksi, Y.; Ahmadi, Z. A.; Cabrera-Orefice, A.; Eyiama, A.; Kellermann, T.; Rugarli, E. I.; Brandt, U.; Meinecke, M.; Langer, T.
10.1101/2021.12.12.470907 — molecular biology — Posted on 2021-12-12
2385 Ubiquitin proteomics reveals critical targets of the Nse1 RING domain in rDNA and genome stability
Ibars, E.; Belli, G.; Casas, C.; Codina-Fabra, J.; Tarres, M.; Sole-Soler, R.; Ximenez-Embun, P.; Munoz, J.; Colomina, N.; Torres-Rosell, J.
10.1101/2021.12.11.472054 — molecular biology — Posted on 2021-12-12
2386 In silico and functional characterisation of an ultra-rare CFTR mutation identifies novel lasso motif interactions regulating channel gating
Wong, S.; Awatade, N.; Astore, M.; Allan, K.; Carnell, M.; Slapetova, I.; Chen, P.-c.; Capraro, A.; Fawcett, L.; Whan, R.; Griffith, R.; Ooi, C.; Kuyucak, S.; Jaffe, A.; Waters, S.
10.1101/2021.12.12.472297 — molecular biology — Posted on 2021-12-12
2388 A two-component protein condensate of EGFR and Grb2 regulates Ras activation at the membrane
Lin, C.-W.; Nocka, L. M.; Stinger, B.; DeGrandchamp, J.; Lew, N.; Alvarez, S.; Phan, H.; Kondo, Y.; Kuriyan, J.; Groves, J. T.
10.1101/2021.12.12.472247 — biophysics — Posted on 2021-12-12
2389 ClusTRace, a bioinformatic pipeline for analyzing clusters in virus phylogenies
Plyusnin, I.; Nguyen, P. T. T.; Sironen, T.; Vapalahti, O.; Smura, T.; Kant, R.
10.1101/2021.12.09.471941 — bioinformatics — Posted on 2021-12-12
2390 NFE2L1-mediated proteasome function protects from ferroptosis
Kotschi, S.; Jung, A.; Willemsen, N.; Ofoghi, A.; Proneth, B.; Conrad, M.; Bartelt, A.
10.1101/2021.12.12.472274 — biochemistry — Posted on 2021-12-12
2392 Identification of novel Ebola virus inhibitors using biologically contained virus
Vanmechelen, B.; Stroobants, J.; Chiu, W.; Schepers, J.; Marchand, A.; Chaltin, P.; Vermeire, K.; Maes, P.
10.1101/2021.12.09.471933 — microbiology — Posted on 2021-12-12
2393 The T cell receptor repertoire reflects the dynamics of the immune response to vaccination
Mohammed, K.; Meadows, A.; Hatem, S.; Simon, V.; Jayaprakash, A. D.; Sachidanandam, R.
10.1101/2021.12.09.471735 — immunology — Posted on 2021-12-12
2397 The human thalamus orchestrates neocortical oscillations during NREM sleep.
Schreiner, T.; Kaufmann, E.; Noachtar, S.; Mehrkens, J.-H.; Staudigl, T.
10.1101/2021.12.11.471766 — neuroscience — Posted on 2021-12-12
2398 Multiple genes in cis mediate the effects of a single chromatin accessibility variant on aberrant synaptic development and function in human neurons
Zhang, S.; Zhang, H.; Forrest, M.; Zhou, Y.; Bagchi, V. A.; Kozlova, A.; Santos, M. D.; Piguel, N.; Dionisio, L. E.; Sanders, A. R.; Pang, Z. P.; He, X.; Penzes, P.; Duan, J.
10.1101/2021.12.11.472229 — genetics — Posted on 2021-12-12
2399 Insights into bear evolution from a Pleistocene polar bear genome
Lan, T.; Leppala, K.; Tomlin, C.; Talbot, S. L.; Sage, G. K.; Farley, S.; Shideler, R. T.; Bachmann, L.; Wiig, O.; Albert, V. A.; Salojarvi, J.; Mailund, T.; Drautz-Moses, D. I.; Schuster, S. C.; Herrera-Estrella, L.; Lindqvist, C.
10.1101/2021.12.11.472228 — evolutionary biology — Posted on 2021-12-12
2400 Metabolic reconstitution by a gnotobiotic microbiota varies over the circadian cycle
Hoces, D.; Lan, J.; Sun, W.; Geiser, T.; Cappio, E.; Arnoldini, M.; Nowok, S.; Macpherson, A. J.; Stecher, B.; Zenobi, R.; Hardt, W.-D.; Wolfrum, C.; Slack, E.
10.1101/2021.09.08.456534 — microbiology — Posted on 2021-12-11
2401 Disruption in structural-functional network repertoire and time resolved subcortical-frontoparietal connectivity in disorders of consciousness
Panda, R.; Thibaut, A.; Lopez-Gonzalez, A.; Escrichs, A.; Bahri, M. A.; Hillebrand, A.; Deco, G.; Laureys, S.; Gosseries, O.; Annen, J.; Tewarie, P.
10.1101/2021.12.10.472068 — neuroscience — Posted on 2021-12-12
2406 Naturally occurring combinations of receptors from single cell transcriptomics in endothelial cells
Domanskyi, S.; Hakansson, A.; Meng, M.; Pham, B. K.; Graff Zivin, J. S.; Piermarocchi, C.; Paternostro, G.; Ferrara, N.
10.1101/2021.01.04.425317 — systems biology — Posted on 2021-12-11
2409 The systematic assessment of completeness of public metadata accompanying omics studies
Huang, Y.-N.; Rajesh, A.; Ayyala, R.; Sarkar, A.; Guo, R.; Ling, E.; Nakashidze, I.; Wong, M. Y.; Hu, J.; Nosov, A.; Chang, Y.; Abedalthagafi, M. S.; Mangul, S.
10.1101/2021.11.22.469640 — bioinformatics — Posted on 2021-12-11
2410 ISSRseq: an extensible method for reduced representation sequencing
Sinn, B. T.; Simon, S. J.; Santee, M. V.; DiFazio, S. P.; Fama, N. M.; Barrett, C. F.
10.1101/2020.12.21.423774 — genomics — Posted on 2021-12-11
2411 A comprehensive catalogue of regulatory variants in the cattle transcriptome
Liu, S.; Gao, Y.; Canela-Xandri, O.; Wang, S.; Yu, Y.; Cai, W.; Li, B.; Xiang, R.; Chamberlain, A. J.; Pairo-Castineira, E.; D'Mellow, K.; Rawlik, K.; Xia, C.; Yao, Y.; Navarro, P.; Rocha, D.; Li, X.; Yan, Z.; Li, C.; Rosen, B. D.; Van Tassell, C. P.; Vanraden, P. M.; Zhang, S.; Ma, L.; Cole, J. B.; Liu, G. E.; Tenesa, A.; Fang, L.
10.1101/2020.12.01.406280 — genomics — Posted on 2021-12-11
2412 Long read sequencing reveals sequential complex rearrangements driven by Hepatitis B virus integration
Wang, S.; Lin, J.; Yang, X.; Li, Z.; Xu, T.; Jia, P.; Wang, T.; Wang, B.; Hu, L.; Ye, K.
10.1101/2021.12.09.471697 — genomics — Posted on 2021-12-11
2415 Odor motion sensing enables complex plume navigation
Kadakia, N.; Demir, M.; Michaelis, B. T.; Reidenbach, M. A.; Clark, D. A.; Emonet, T.
10.1101/2021.09.29.462473 — neuroscience — Posted on 2021-12-11
2416 Chloride-dependent mechanisms of multimodal sensory discrimination and neuropathic sensitization in Drosophila
Himmel, N. J.; Sakurai, A.; Letcher, J. M.; Patel, A. A.; Bhattacharjee, S.; Benson, M. N.; Gray, T. R.; Cymbalyuk, G. S.; Cox, D. N.
10.1101/2021.12.10.472093 — neuroscience — Posted on 2021-12-11
2417 Sequence diversity in the 3' untranslated region of alphavirus modulates IFIT2-dependent restriction in a cell type-dependent manner
Hickson, S. E.; Brekke, E.; Schwerk, J.; Salukhe, I.; Zaver, S. A.; Woodward, J. J.; Savan, R.; Hyde, J. L.
10.1101/2021.12.10.472177 — microbiology — Posted on 2021-12-11
2419 Single-fiber nucleosome density shapes the regulatory output of a mammalian chromatin remodeling enzyme
Abdulhay, N. J.; Hsieh, L. J.; McNally, C. P.; Ketavarapu, M.; Kasinathan, S.; Nanda, A. S.; Ostrowski, M. S.; Wu, K.; Moore, C. M.; Goodarzi, H.; Narlikar, G. J.; Ramani, V.
10.1101/2021.12.10.472156 — genomics — Posted on 2021-12-11
2420 Phylogenomic analyses of Snodgrassella isolates from honeybees and bumblebees reveals taxonomic and functional diversity
Cornet, L.; Cleenwerck, I.; Praet, J.; Leonard, R.; Vereecken, N. J.; Michez, D.; Smagghe, G. J.; BAURAIN, D.; Vandammme, P.
10.1101/2021.12.10.472130 — genomics — Posted on 2021-12-11
2421 Mouse models of NADK2 deficiency analyzed for metabolic and gene expression changes to elucidate pathophysiology
Murray, G.; Bais, P.; Hatton, C.; Tadenev, A.; Morelli, K.; Schroder, D.; Doty, R.; Fiehn, O.; John, S.; Bult, C.; Cox, G.; Burgess, R.
10.1101/2021.12.10.472125 — genetics — Posted on 2021-12-11
2425 Myosin phosphatase target subunit 1 governs integrity of the embryonic gut epithelium to circumvent atresia development in medaka, Oryzias latipes
Kobayashi, D.; Matsuo, K.; Kimura, T.; Ansai, S.; Yokoi, H.; Takashima, S.; Kitagawa, T.; Kage, T.; Narita, T.; Jindo, T.; Kinoshita, M.; Naruse, K.; Nakajima, Y.; Shigeta, M.; Sakaki, S.; Inoue, S.; Saba, R. S.; Yamada, K.; Yokoyama, T.; Ishikawa, Y. ,; Araki, K.; Saga, Y.; Takeda, H.; Yashiro, K.
10.1101/2021.12.10.472183 — developmental biology — Posted on 2021-12-11
2427 Leptin-mediated suppression of food intake by conserved Glp1r-expressing neurons prevents obesity
Rupp, A. C.; Tomlinson, A. J.; Affinati, A. H.; True, C.; Lindsley, S. R.; Kirigiti, M. A.; MacKenzie, A.; Li, C.; Knudsen, L. B.; Olson, D. P.; Kievit, P.; Myers, M. G.
10.1101/2021.12.10.472115 — neuroscience — Posted on 2021-12-11
2429 3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib
Meraz, I. M.; Majidi, M.; Fang, B.; Meng, F.; Gao, L.; Shao, R.; Song, R.; Li, F.; Ha, M. J.; Wang, Q.; Wang, J.; Shpall, E. J.; Jung, S. Y.; Haderk, F.; Gui, P.; Riess, J. W.; Olivas, V.; Bivona, T. G.; Roth, J. A.
10.1101/2021.12.10.472153 — cancer biology — Posted on 2021-12-11
2430 Genetic Subtypes of Smoldering Multiple Myeloma are associated with Distinct Pathogenic Phenotypes and Clinical Outcomes
Bustoros, M.; Anand, S.; Sklavenitis-Pistofidis, R.; Redd, R.; Boyle, E. M.; Zhitomirsky, B.; Dunford, A. J.; Tai, Y.-T.; Chavda, S. J.; Boehner, C.; Neuse, C. J.; Rahmat, M.; Dutta, A.; Casneuf, T.; Verona, R.; Kastritis, E.; Trippa, L.; Stewart, C.; Walker, B. A.; Davies, F. E.; Dimopoulos, M.-A.; Bergsagel, L.; Yong, K.; Morgan, G. J.; Aguet, F.; Getz, G.; Ghobrial, I. M.
10.1101/2021.12.10.471975 — cancer biology — Posted on 2021-12-11
2432 Geometrical frustration of phase-separated domains in Coscinodiscus diatom frustules
Feofilova, M.; Schüepp, S.; Schmid, R.; Hacker, F.; Spanke, H. T.; Bain, N.; Jensen, K. E.; Dufresne, E. R.
10.1101/2021.12.10.472144 — biophysics — Posted on 2021-12-11
2433 Chromosome-level genome assembly of the functionally extinct northern white rhinoceros (Ceratotherium simum cottoni).
Wang, G.; Braendl, B.; Rohrandt, C.; Hong, K.; Pang, A.; Lee, J.; Lewin, H.; Migliorelli, G.; Stanke, M.; Schwab, R.; Ford, S.; Pollmann, I.; Schuldt, B.; Houck, M.; Ryder, O.; Meissner, A.; Loring, J.; Mueller, F.-J.; Korody, M.
10.1101/2021.12.11.472206 — genomics — Posted on 2021-12-11
2434 The 3D architecture of the pepper (Capsicum annum) genome and its relationship to function and evolution
Liao, Y.; Wang, J.; Zhu, Z.; Liu, Y.; Chen, J.; Zhou, Y.; Liu, F.; Lei, J.; Gaut, B. S.; Cao, B.; Emerson, J. J.; Chen, C.
10.1101/2021.12.10.470457 — genomics — Posted on 2021-12-11
2436 Polyclonal pathogen populations accelerate the evolution of antibiotic resistance in patients
Diaz Caballero, J.; Wheatley, R. M.; Kapel, N.; Lopez-Causape, C.; Van der Schalk, T.; Quinn, A.; Recanatini, C.; Britto Xavier, B.; Timbermont, L.; Kluytmans, J.; Ruzin, A.; Esser, M.; Malhotra-Kumar, S.; Oliver, A.; MacLean, R. C.; WP3A working group,
10.1101/2021.12.10.472119 — evolutionary biology — Posted on 2021-12-11
2437 Circadian clock function does not require the histone methyltransferase MLL3
Baxter, M.; Poolman, T.; Cunningham, P.; Hunter, A. L.; Voronkov, M.; Kitchen, G. B.; Goosey, L.; Begley, N.; Kay, D.; Hespe, A.; Maidstone, R.; Loudon, A.; Ray, D. W.
10.1101/2021.12.10.472092 — molecular biology — Posted on 2021-12-11
2442 Cerebrospinal fluid formation is controlled by membrane transporters to modulate intracranial pressure
Oernbo, E. K.; Steffensen, A. B.; Khamesi, P. R.; Toft-Bertelsen, T. L.; Barbuskaite, D.; Vilhardt, F.; Gerkau, N. J.; Tritsaris, K.; Simonsen, A. H.; Lolansen, S. D.; Andreassen, S. N.; Hasselbalch, S. G.; Zeuthen, T.; Rose, C. R.; Kurtcuoglu, V.; MacAulay, N.
10.1101/2021.12.10.472067 — neuroscience — Posted on 2021-12-11
2443 Transcriptomic heterogeneity of Sox2-expressing pituitary cells
Fletcher, P. A.; Previde, R. M.; Smiljanic, K.; Sherman, A.; Coon, S. L.; Stojilkovic, S. S.
10.1101/2021.12.10.472137 — neuroscience — Posted on 2021-12-11
2444 Develop an efficient and specific AAV-based labeling system for Muller glia in mice
Gao, Y.; Fang, K.; Yan, Z.; Zhang, H.; Geng, G.; Wu, W.; Xu, D.; Zhang, H.; Zhong, N.; Wang, Q.; Cai, M.; Zuo, E.; Yang, H.
10.1101/2021.12.10.472182 — neuroscience — Posted on 2021-12-11
2445 The protein organization of a red blood cell
Sae-Lee, W.; McCafferty, C. L.; Verbeke, E. J.; Havugimana, P. C.; Papoulas, O.; McWhite, C. D.; Houser, J. R.; Vanuytsel, K.; Murphy, G.; Drew, K.; Emili, A.; Taylor, D. W.; Marcotte, E. M.
10.1101/2021.12.10.472004 — systems biology — Posted on 2021-12-11
2448 Improving genomically recoded Escherichia coli for the production of proteins containing non-canonical amino acids
Perez, J. G.; Carlson, E. D.; Weisser, O.; Kofman, C.; Seki, K.; Des Soye, B. J.; Karim, A. S.; Jewett, M. C.
10.1101/2021.12.10.472167 — synthetic biology — Posted on 2021-12-11
2450 Programmed knockout mutation of liver fluke granulin, Ov-grn-1, attenuates virulence and impedes malignant transformation during chronic opisthorchiasis
Chaiyadet, S.; Tangkawattana, S.; Smout, M. J.; Ittiprasert, W.; Mann, V. H.; Deenonpoe, R.; Arunsan, P.; Loukas, A.; Brindley, P. J.; Laha, T.
10.1101/2021.12.10.472085 — cancer biology — Posted on 2021-12-11
2452 Timing of exposure is critical in a highly sensitive model of SARS-CoV-2 transmission
Ganti, K.; Lowen, A. C.; Ferreri, L. M.; Lee, C.-Y.; Bair, C. R.; Delima, G. K.; Holmes, K. E.; Suthar, M. S.
10.1101/2021.12.08.471873 — microbiology — Posted on 2021-12-11
2453 Macrophage cell lines and murine infection by Salmonella Typhi L-form bacteria
Das, S.; Ganguli, D.; Chakraborty, S.; Chakraborty, S.; Pal, A.; Gope, A.
10.1101/2021.12.10.472194 — microbiology — Posted on 2021-12-11
2454 Sub-communities of the vaginal ecosystem in pregnant and non-pregnant women.
Symul, L.; Jeganathan, P.; Costello, E.; France, M.; Bloom, S. M.; Ravel, J.; Kwon, D. S.; Relman, D. A.; Holmes, S. P.
10.1101/2021.12.10.471327 — microbiology — Posted on 2021-12-11
2456 A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues
Saul, D.; Kosinsky, R. L.; Atkinson, E. J.; Doolittle, M. L.; Zhang, X.; LeBrasseur, N.; Pignolo, R.; Robbins, P.; Niedernhofer, L.; Ikeno, Y.; Jurk, D.; Passos, J.; Hickson, L.; Xue, A.; Monroe, D.; Tchkonia, T.; Kirkland, J. L.; Farr, J. N.; Khosla, M.D, S.
10.1101/2021.12.10.472095 — cell biology — Posted on 2021-12-11
2457 Syntaxin 5 determines Weibel-Palade body size and Von Willebrand factor secretion by controlling Golgi architecture
Kat, M.; Karampini, E.; Hoogendijk, A. J.; Bürgisser, P. E.; Mulder, A. A.; van Alphen, F. P.; Olins, J.; Geerts, D.; van den Biggelaar, M.; Margadant, C.; Voorberg, J.; Bierings, R.
10.1101/2021.12.10.472050 — cell biology — Posted on 2021-12-11
2461 SMER28 attenuates PI3K/mTOR signaling by direct inhibition of PI3K p110 delta
Kirchenwitz, M.; Stahnke, S.; Prettin, S.; Borowiak, M.; Birchmeier, C.; Rottner, K.; Stradal, T. E. B.; Steffen, A.
10.1101/2021.12.10.471916 — cell biology — Posted on 2021-12-11
2462 Nanoscale architecture and coordination of actin cores within the sealing zone of human osteoclasts
Portes, M.; Mangeat, T.; Escalier, N.; Raynaud-Messina, B.; Thibault, C.; Maridonneau-Parini, I.; Verollet, C.; Poincloux, R.
10.1101/2021.12.09.471901 — cell biology — Posted on 2021-12-11
2463 Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions
Yifrach, E.; Holbrook-Smith, D.; Bürgi, J.; Othman, A.; Eisenstein, M.; Van Roermund, C. W. T.; Visser, W.; Tirosh, A.; Bibi, C.; Galor, S.; Weil, U.; Fadel, A.; Peleg, Y.; Waterham, H.; Wanders, R. J.; Wilmanns, M.; Zamboni, N.; Schuldiner, M.; Zalckvar, E.
10.1101/2021.12.08.471723 — cell biology — Posted on 2021-12-11
2464 A short prokaryotic argonaute cooperates with membrane effector to confer antiviral defense
Zeng, Z.; Chen, Y.; Pinilla-Redondo, R.; Shah, S. A.; Zhao, F.; Wang, C.; Hu, Z.; Zhang, C.; Whitaker, R.; She, Q.; Han, W.
10.1101/2021.12.09.471704 — microbiology — Posted on 2021-12-11
2466 Dopamine D2Rs Coordinate Cue-Evoked Changes in Striatal Acetylcholine Levels
Kellendonk, C.; Martyniuk, K. M.; Torres-Herraez, A.; Rubinstein, M.; Labouesse, M. A.
10.1101/2021.12.08.471871 — neuroscience — Posted on 2021-12-11
2467 Boron Supply Restores Aluminum-Blocked Auxin Transport by Modulation PIN2 Trafficking in the Arabidopsis Roots
Tao, L.; Feng, Y.; Li, Y.; Li, X.; Meng, X.; Li, M.; Pirayesh, N.; Mahmud, S.; Shabala, S.; Baluska, F.; Shi, L.; Yu, M.
10.1101/2021.12.09.471968 — physiology — Posted on 2021-12-11
2468 The minor spliceosome offers a therapeutically viable target for the treatment of a broad spectrum of cancers
Doggett, K.; Morgan, K. J.; Mieruszynski, S.; Williams, B. B.; Olthof, A. M.; Garnham, A. L.; Milevskiy, M. J. G.; Whitehead, L.; Coates, J.; Buchert, M.; O'Donoghue, R. J.; Hall, T. E.; Gong, Z.; Putoczki, T. L.; Ernst, M.; Sutherland, K. D.; Kanadia, R. N.; Heath, J. K.
10.1101/2021.12.09.469623 — cancer biology — Posted on 2021-12-11
2470 Active neural coordination of motor behaviors with internal states
Zhang, Y. S.; Takahashi, D. Y.; El Hady, A.; Liao, D. A.; Ghazanfar, A. A.
10.1101/2021.12.10.472142 — neuroscience — Posted on 2021-12-11
2477 Poly ADP-ribosylation of SET8 leads to aberrant H4K20 methylation domains in mammalian cells
Esteve, P.-O.; Udayakumaran Nair Sunitha Kumary, V.; Ruse, C.; Chin, H. G.; Pradhan, S.
10.1101/2021.11.13.468478 — molecular biology — Posted on 2021-12-11
2488 Cell-specific Bioorthogonal Tagging of Glycoproteins
Cioce, A.; Calle, B.; Rizou, T.; Lowery, S.; Bridgeman, V.; Mahoney, K.; Marchesi, A.; Bineva-Todd, G.; Flynn, H.; Li, Z.; Tastan, O. Y.; Roustan, C.; Soro-Barrio, P.; Wood, T.; Keenan, T.; Both, P.; Huang, K.; Parmeggiani, F.; Snijders, A. P.; Skehel, M.; Kjaer, S.; Fascione, M. A.; Bertozzi, C.; Flitsch, S. L.; Malaker, S. A.; Malanchi, I.; Schumann, B.
10.1101/2021.07.28.454135 — synthetic biology — Posted on 2021-12-11
2489 Improving Lab Culture Through Self-Assessment: A Case Study
Hernandez, S.; Mumme, R.; Court, L.; El Basha, D.; Gay, S.; Marquez, B.; Xiao, Y.; Huang, K.; Baroudi, H.; Cao, W.; Cardenas, C.; Douglas, R.; Duryea, J.; Kaffey, Z.; Mann, D.; Nealon, K.; Netherton, T.; Nguyen, C.; Oh, K.; Olanrewaju, A.; Sjogreen, C.; Rhee, D. J.; Yang, J.; Yu, C.; Zhang, L. J.; Zhao, Y.; Ziyaee, H.; Gronberg, M.
10.1101/2021.12.08.471870 — scientific communication and education — Posted on 2021-12-11
2490 Multiplex knockout of trichome-regulating MYB duplicates in hybrid poplar using a single gRNA
Bewg, W. P.; Harding, S. A.; Engle, N.; Vaidya, B. N.; Zhou, R.; Reeves, J.; Horn, T. W.; Joshee, N.; Jenkins, J. W.; Shu, S.; Barry, K. W.; Yoshinaga, Y.; Grimwood, J.; Schmitz, R. J.; Schmutz, J.; Tschaplinski, T.; Tsai, C.-J.
10.1101/2021.09.09.459666 — plant biology — Posted on 2021-12-11
2492 Positive Selection and Heat-Response Transcriptomes Reveal Adaptive Features of the Arabidopsis Desert Relative, Anastatica hierochuntica
Eshel, G.; Duppen, N.; Wang, G.; Oh, D.-H.; Kazachkova, Y.; Herzyk, P.; Amtmann, A.; Gordon, M.; Chalifa-Caspi, V.; Oscar, M. A.; Bar-David, S.; Marshall-Colon, A.; Dassanayake, M.; Barak, S.
10.1101/2021.05.23.445339 — plant biology — Posted on 2021-12-11
2493 XopQ induced stromule formation in Nicotiana benthamiana is causally linked to ETI signaling and depends on ADR1 and NRG1
Prautsch, J.; Erickson, J. L.; Özyürek, S.; Gormannns, R.; Franke, L.; Parker, J. E.; Stuttmann, J.; Schattat, M. H.
10.1101/2021.12.06.471425 — plant biology — Posted on 2021-12-11
2498 HAYSTAC: A Bayesian framework for robust and rapid species identification in high-throughput sequencing data
Dimopoulos, E. A.; Carmagnini, A.; Velsko, I. M.; Warinner, C.; Larson, G.; Frantz, L. A. F.; Irving-Pease, E. K.
10.1101/2020.12.16.419085 — bioinformatics — Posted on 2021-12-11
2499 DeepMAPS: Single-cell biological network inference using heterogeneous graph transformer
Ma, A.; Wang, X.; Wang, C.; Li, J.; Xiao, T.; Wang, J.; Li, Y.; Liu, Y.; Chang, Y.; Wang, D.; Jiang, Y.; Li, J.; Su, L.; Gu, S.; Xin, G.; Li, Z.; Liu, B.; Xu, D.; Ma, Q.
10.1101/2021.10.31.466658 — bioinformatics — Posted on 2021-12-11
2501 Rapid multilocus adaptation of clonal cabbage leaf curl virus populations to Arabidopsis thaliana
Hoyer, J. S.; Wilkins, O. W.; Munshi, A.; Wiese, E.; Dubey, D.; Renard, S.; Mortensen, K. R. H.; Dye, A. E.; Carbone, I.; Duffy, S.; Ascencio-Ibanez, J. T.
10.1101/2021.11.29.468282 — evolutionary biology — Posted on 2021-12-11
2506 Developmental dynamics of the neural crest-mesenchymal axis in creating the thymic microenvironment
Handel, A. E.; Cheuk, S.; Dhalla, F.; Maio, S.; Hubscher, T.; Rota, I.; Deadman, M. E.; Ekwall, O.; Lutolf, M.; Weinberg, K.; Hollander, G.
10.1101/2021.11.08.467624 — immunology — Posted on 2021-12-11
2508 Imaging Three-Dimensional Brain Organoid Architecture from Meso- to Nanoscale across Development
Rodriguez-Gatica, J. E.; Iefremova, V.; Sokhranyaeva, L.; Yeung, S. W. C. A.; Breitkreuz, Y.; Bruestle, O.; Schwarz, M. K.; Kubitscheck, U.
10.1101/2021.12.03.471084 — neuroscience — Posted on 2021-12-11
2509 Automated Analysis of Low-Field Brain MRI in Cerebral Malaria
Tu, D.; Goyal, M. S.; Dworkin, J. D.; Kampondeni, S.; Vidal, L.; Biondo-Savin, E.; Juvvadi, S.; Raghavan, P.; Nicholas, J.; Chetcuti, K.; Clark, K.; Robert-Fitzgerald, T.; Satterthwaite, T. D.; Yushkevich, P.; Davatzikos, C.; Erus, G.; Tustison, N. J.; Postels, D. G.; Taylor, T. E.; Small, D. S.; Shinohara, R. T.
10.1101/2020.12.23.424020 — neuroscience — Posted on 2021-12-11
2510 Transmission-selective muscle pathology induced by active propagation of mutant huntingtin across the human neuromuscular synapse
Dinamarca Ceballos, M.; Colombo, L.; Brykczynska, U.; Grimm, A.; Tousiaki, E. N.; Fruh, I.; Hossain, I.; Gabriel, D.; Eckert, A.; Mueller, M.; Pecho-Vrieseling, E.
10.1101/2021.07.28.454044 — neuroscience — Posted on 2021-12-11
2515 Random forest modelling of neuropathological features identifies microglial activation as an accurate pathological classifier of C9orf72-related amyotrophic lateral sclerosis
Rifai, O. M.; Longden, J.; O'Shaughnessy, J.; Sewell, M. D.; McDade, K.; Daniels, M. J.; Abrahams, S.; Chandran, S.; McColl, B.; Sibley, C. R.; Gregory, J. M.
10.1101/2021.12.10.471808 — neuroscience — Posted on 2021-12-10
2520 Cognitive experience alters cortical involvement in navigation decisions
Harvey, C. D.; Arlt, C.; Barroso-Luque, R.; Kira, S.; Bruno, C. A.; Xia, N.; Chettih, S. N.; Soares, S.; Pettit, N. L.
10.1101/2021.12.10.472106 — neuroscience — Posted on 2021-12-10
2521 RAS mutation patterns arise from tissue-specific responses to distinct oncogenic signaling
Erdogan, O.; Pershing, N. L. K.; Kaltenbrun, E.; Newman, N. J.; Everitt, J.; Counter, C.
10.1101/2021.12.10.472098 — cancer biology — Posted on 2021-12-10
2522 Electrically Controlling and Optically Observing the Membrane Potential of Supported Lipid Bilayers
Yudovich, S.; Marzouqe, A.; Kantorovitsch, J.; Teblum, E.; Chen, T.; Enderlein, J.; Miller, E. W.; Weiss, S.
10.1101/2021.12.10.472087 — biophysics — Posted on 2021-12-10
2523 Urine proteomics as a non-invasive approach to monitor exertional rhabdomyolysis during military training
Carneiro, A.; Macedo-da-Silva, J.; Santiago, V. F.; de Oliveira, G. S.; Guimaraes, T.; Mendoca, C. F.; Branquinho, J. L. d. O.; Lucena, C. V.; Osorio, J. B.; Pernambuco, E.; Moreira, J. C.; Pesquero, J. B.; Pereira, M. D.; Palmisano, G.
10.1101/2021.12.10.471761 — biochemistry — Posted on 2021-12-10
2528 New insights into colorectal cancer liver metastasis carcinogenesis and its effect with moxibustion
Song, Y.; Pei, L.; Guo, J.; Zhuang, Y.; Wang, Y.; Zhao, T.; Chen, L.; Zhou, J.; Sun, J.
10.1101/2021.12.08.471188 — cancer biology — Posted on 2021-12-10
2529 Awake mouse brain photoacoustic and optical imaging through a transparent ultrasound cranial window
Mirg, S.; Chen, H.; Turner, K. L.; Liu, J.; Gluckman, B.; Drew, P. J.; Kothapalli, S.-R.
10.1101/2021.12.08.471795 — bioengineering — Posted on 2021-12-10
2530 Using ultraconserved elements to reconstruct the termite tree of life
Hellemans, S.; Wang, M.; Hasegawa, N.; Sobotnik, J.; Scheffrahn, R. H.; Bourguignon, T.
10.1101/2021.12.09.472027 — evolutionary biology — Posted on 2021-12-10
2533 Towards Biophysical Markers of Depression Vulnerability
Pinotsis, D.; Fitzgerald, S.; See, C.; Sementsova, A.; Widge, A. S.
10.1101/2021.12.08.471836 — neuroscience — Posted on 2021-12-10
2537 Condensin compacts DNA in 15 nm steps and requires FACT for extrusion on chromatin
Sudhakar, S.; Fisher, G. L.; Escribano, P. G.; Luis, J. G.; Cutts, E.; Cawood, C.; Aragon, L.; Rueda, D. S.
10.1101/2021.09.15.460217 — biophysics — Posted on 2021-12-10
2538 A nanobody-based toolset to monitor and modify the mitochondrial GTPase Miro1
Fagbadebo, F. O.; Kaiser, P. D.; Zittlau, K.; Bartlick, N.; Wagner, T. R.; Froehlich, T.; Jarjour, G.; Nueske, S.; Scholz, A.; Traenkle, B.; Macek, B.; Rothbauer, U.
10.1101/2021.12.10.472061 — cell biology — Posted on 2021-12-10
2542 Isolation and characterization of fucosylated extracellular vesicles based on a novel GlyExo-Capture technique
Li, B.; Hao, K.; Li, Z.; Ma, C.; Li, H.; Du, W.; Sun, L.; Jia, T.; Liu, A.; Li, Y.; Xu, L.; Gao, Q.; Yang, R.; Lin, C.
10.1101/2021.12.09.471505 — cancer biology — Posted on 2021-12-10
2546 North and East African mitochondrial genetic variation needs further characterization towards precision medicine
Fähnrich, A.; Stephan, I.; Hirose, M.; Awadelkareem, M. A.; Ibrahim, S.; Busch, H.; Wohlers, I.
10.1101/2021.12.10.472079 — genetics — Posted on 2021-12-10
2554 Spatially regulated protease activity in lymph nodes renders B cell follicles a sanctuary for retention of intact antigens
Aung, A.; Cui, A.; Soleimany, A. P.; Bukenya, M.; Lee, H.; Cottrell, C. A.; Silva, M.; Kirkpatrick, J. D.; Amlashi, P.; Remba, T. K.; Xiao, S.; Froehle, L. M.; Abraham, W.; Adams, J.; Suh, H.; Huyett, P.; Kwon, D. S.; Hacohen, N.; Schief, W. R.; Bhatia, S. N.; Irvine, D. J.; Gregory, J. R.
10.1101/2021.11.15.468669 — immunology — Posted on 2021-12-10
2559 Engineered biological neural networks on high density CMOS micro electrode arrays
Duru, J.; Kuechler, J.; Ihle, S. J.; Forro, C.; Bernardi, A.; Girardin, S.; Hengsteler, J.; Wheeler, S.; Voros, J.; Ruff, T.
10.1101/2021.12.09.471944 — neuroscience — Posted on 2021-12-10
2561 Seeing the future: predictive control in neural models of ocular accommodation
Read, J. C. A.; Kaspiris-Rousellis, C.; Wood, T.; Wu, B.; Vlaskamp, B. N. S.; Schor, C. M.
10.1101/2021.12.09.471909 — neuroscience — Posted on 2021-12-10
2563 Nandrolone Decanoate supplementation promotes AMPK activation and divergent brain connectivity rearrangements in adult and aged mice.
Strogulski, N. R.; Kopczynski, A.; Girelli, V.; Carteri, R. B.; Sartor, M.; Venturin, G.; Greggio, S.; da Costa, J. C.; De Bastiani, M. A.; Rodolphi, M. S.; Portela, L. V.
10.1101/2021.10.19.465014 — neuroscience — Posted on 2021-12-10
2564 Leaders are made: Learning acquisition of consistent leader-follower relationships depends on implicit haptic interactions.
Takai, A.; Fu, Q.; Doibata, Y.; Lisi, G.; Tsuchiya, T.; Mojtahedi, K.; Yoshioka, T.; Kawato, M.; Morimoto, J.; Santello, M.
10.1101/2021.12.09.471486 — neuroscience — Posted on 2021-12-10
2568 Topologically controlled circuits of human iPSC-derived neurons for electrophysiology recordings
Girardin, S.; Clement, B.; Ihle, S. J.; Weaver, S.; Petr, J. B.; Mateus, J. C.; Duru, J.; Forro, C.; Ruff, T.; Fruh, I.; Müller, M.; Vörös, J.
10.1101/2021.12.10.472063 — neuroscience — Posted on 2021-12-10
2570 Iron treatment induces defense responses and disease resistance against Magnaporthe oryzae in rice
Sanchez-Sanuy, F.; Mateluna Cuadra, R.; Okada, K.; Sacchi, G. A.; Campo, S.; San Segundo, B.
10.1101/2021.12.09.471912 — plant biology — Posted on 2021-12-10
2572 Effects of sub-lethal single, simultaneous, and sequential abiotic stresses on phenotypic traits of Arabidopsis thaliana
Morales, A.; de Boer, H. J.; Douma, J. C.; Elsen, S.; Engels, S.; Glimmerveen, T.; Sajeev, N.; Huber, M.; Luimes, M.; Luitjens, E.; Raatjes, K.; Hsieh, C.; Teapal, J.; Wildenbeest, T.; Jiang, Z.; Pareek, A.; Singla-Pareek, S.; Yin, X.; Evers, J. B.; Anten, N. P. R.; van Zanten, M.; Sasidharan, R.
10.1101/2021.12.10.472073 — plant biology — Posted on 2021-12-10
2575 Predicting genes associated with RNA methylation pathways using machine learning
Tsagkogeorga, G.; Santos Rosa, H.; Alendar, A.; Leggate, D.; Rausch, O.; Kouzarides, T.; Weisser, H.; Han, N.
10.1101/2021.12.10.472055 — bioinformatics — Posted on 2021-12-10
2579 Cryptic local adaptation is pervasive across environmental and evolutionary gradients
Sparks, M. M.; Kraft, J. C.; Blackstone, K. M.; McNickle, G. G.; Christie, M. R.
10.1101/2021.12.05.471216 — ecology — Posted on 2021-12-10
2580 OSBP-mediated cholesterol transfer determines epithelial polarity and associated cargo secretion
Kovacs, D.; Gay, A.-S.; Fleuriot, L.; Debayle, D.; Dias Araujo, A. R.; Patel, A. J.; Mesmin, B.; Luton, F.; Antonny, B.
10.1101/2021.12.09.471984 — cell biology — Posted on 2021-12-10
2582 Interferon Resistance of Emerging SARS-CoV-2 Variants
Guo, K.; Barrett, B. S.; Mickens, K. L.; Vladar, E. K.; Morrison, J. H.; Hasenkrug, K. J.; Poeschla, E. M.; Santiago, M. L.
10.1101/2021.03.20.436257 — microbiology — Posted on 2021-12-10
2587 Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2
Shi, G.; Chiramel, A. I.; Majdoul, S.; Lai, K. K.; Dempsey, T.; Kenney, A.; Zani, A.; Eddy, A.; Zhang, L.; Das, S.; Beare, P. A.; Andresson, T.; Kar, S.; Yount, J. S.; Best, S. M.; Compton, A. A.
10.1101/2021.04.15.440067 — microbiology — Posted on 2021-12-10
2594 Efficient ancestry and mutation simulation with msprime 1.0
Baumdicker, F.; Bisschop, G.; Goldstein, D.; Gower, G.; Ragsdale, A. P.; Tsambos, G.; Zhu, S.; Eldon, B.; Ellerman, C. E.; Galloway, J. G.; Gladstein, A. L.; Gorjanc, G.; Guo, B.; Jeffery, B.; Kretzschmar, W. W.; Lohse, K.; Matschiner, M.; Nelson, D.; Pope, N. S.; Quinto-Cortes, C. D.; Rodrigues, M. F.; Saunack, K.; Sellinger, T.; Thornton, K.; van Kemenade, H.; Wohns, A. W.; Wong, Y.; Gravel, S.; Kern, A. D.; Koskela, J.; Ralph, P. L.; Kelleher, J.
10.1101/2021.08.31.457499 — genetics — Posted on 2021-12-10
2596 A combined human in silico and CRISPR/Cas9-mediated in vivo zebrafish based approach for supporting gene target validation in early drug discovery
Winter, M. J.; Ono, Y.; Ball, J. S.; Walentinsson, A.; Michaelsson, E.; Tochwin, A.; Scholpp, S.; Tyler, C. R.; Rees, S.; Hetheridge, M. J.; Bohlooly-Y, M.
10.1101/2021.09.14.460241 — molecular biology — Posted on 2021-12-10
2603 Modulation of the Drosophila Transcriptome by Developmental Exposure to Alcohol
Morozova, T. V.; Shankar, V.; MacPherson, R. A.; Mackay, T. F. C.; Anholt, R. R. H.
10.1101/2021.12.09.472007 — genetics — Posted on 2021-12-10
2604 Primary infection by E. multilocularis induces distinct patterns of crosstalk between hepatic regulatory T and natural killer T cells in mice
Yarahmadov, T.; Wang, J.; Sanchez-Talavull, D.; Alvarez Rojas, C. A.; Brodie, T.; Büchi, I.; Keogh, A.; Gottstein, B.; Stroka, D.; Beldi, G.
10.1101/2021.12.08.471874 — immunology — Posted on 2021-12-10
2608 Shared mechanisms of auditory and non-auditory vocal learning in the songbird brain
McGregor, J.; Grassler, A.; Jaffe, P. I.; Jacob, A. L.; Brainard, M.; Sober, S. J.
10.1101/2021.12.09.471883 — neuroscience — Posted on 2021-12-10
2612 Improving Lab Culture Through Self-Assessment: A Case Study
Hernandez, S.; Mumme, R.; Court, L.; El Basha, D.; Gay, S.; Marquez, B.; Xiao, Y.; Huang, K.; Baroudi, H.; Cao, W.; Cardenas, C.; Douglas, R.; Duryea, J.; Kaffey, Z.; Mann, D.; Nealon, K.; Netherton, T.; Nguyen, C.; Oh, K.; Olanrewaju, A.; Sjogreen, C.; Rhee, D. J.; Yang, J.; Yu, C.; Zhang, L. J.; Zhao, Y.; Ziyaee, H.; Gronberg, M.
10.1101/2021.12.08.471870 — scientific communication and education — Posted on 2021-12-10
2614 Skopi: a simulation package for diffractive imaging of noncrystalline biomolecules
Peck, A.; Chang, H.-Y.; Dujardin, A.; Ramalingam, D.; Uervirojnangkoorn, M.; Wang, Z.; Mancuso, A.; Poitevin, F.; Yoon, C. H.
10.1101/2021.12.09.471972 — biophysics — Posted on 2021-12-10
2618 Simultaneous quantification of ankle, muscle, and tendon impedance in humans
Jakubowski, K. L.; Ludvig, D.; Bujnowski, D.; Lee, S.; Perreault, E. J.
10.1101/2021.12.08.471793 — bioengineering — Posted on 2021-12-10
2621 A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes
Toh, H.; Yang, C.; Formenti, G.; Raja, K.; Yan, L.; Tracey, A.; Chow, W.; Howe, K.; Bergeron, L. A.; Zhang, G.; Haase, B.; Mountcastle, J.; Fedrigo, O.; Fogg, J.; Kirilenko, B.; Munegowda, C.; Hiller, M.; Jain, A.; Kihara, D.; Rhie, A.; Phillippy, A. M.; Swanson, S. A.; Jiang, P.; Clegg, D. O.; Jarvis, E. D.; Thomson, J. A.; Stewart, R.; Chaisson, M. J. P.; Bukhman, Y. V.
10.1101/2021.12.08.471837 — genomics — Posted on 2021-12-10
2622 Host immune responses to enzootic and invasive pathogen lineages vary in magnitude, timing, and efficacy
McDonald, C. A.; Becker, C. G.; Lambertini, C.; Toledo, L. F.; Haddad, C. F.; Zamudio, K. R.
10.1101/2021.12.08.471676 — genomics — Posted on 2021-12-10
2627 Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity
McEvoy, C. M.; Murphy, J. M.; Zhang, L.; Clotet-Freixas, S.; Mathews, J. A.; An, J.; Karimzadeh, M.; Pouyabahar, D.; Su, S.; Zaslaver, O.; Rost, H.; Arambewela, M.; Liu, L. Y.; Zhang, S.; Lawson, K. A.; Finelli, A.; Wang, B.; MacParland, S. A.; Bader, G. D.; Konvalinka, A.; Crome, S. Q.
10.1101/2021.12.09.471943 — immunology — Posted on 2021-12-10
2628 Mapping of the autophagosomal degradome identifies IL-7Rα as key cargo in proliferating CD4+ T-cells
Zhou, D.; Borsa, M.; Puleston, D. J.; Zellner, S.; Capera, J.; Sanderson, S.; Jostins, L.; Behrends, C.; Alsaleh, G.; Simon, A. K.
10.1101/2021.12.08.471825 — immunology — Posted on 2021-12-10
2630 Functional modulation of PTH1R activation and signalling by RAMP2
Nemec, K.; Schihada, H.; Kleinau, G.; Zabel, U.; Grushevskyi, E. O.; Scheerer, P.; Lohse, M. J.; Maiellaro, I.
10.1101/2021.12.08.471790 — pharmacology and toxicology — Posted on 2021-12-10
2634 Minor intron splicing efficiency increases with the development of lethal prostate cancer
Augspach, A.; Drake, K.; Roma, L.; Qian, E.; Lee, S. R.; Clarke, D.; Kumar, S.; Jaquet, M.; Gallon, J.; Bolis, M.; Triscott, J.; Galvan, J. A.; Chen, Y.; Thalmann, G.; Kruithof-de Julio, M.; Theurillat, J.-P. P.; Wuchty, S.; Gerstein, M.; Piscuoglio, S.; Kanadia, R.; Rubin, M. A.
10.1101/2021.12.09.471104 — cancer biology — Posted on 2021-12-10
2635 WILD-seq: Clonal deconvolution of transcriptomic signatures of sensitivity and resistance to cancer therapeutics in vivo.
Wild, S. A.; Cannell, I. G.; Kania, K.; CRUK IMAXT Grand Challenge Team, ; Hannon, G. J.; Sawicka, K.
10.1101/2021.12.09.471927 — cancer biology — Posted on 2021-12-10
2637 The Effect of Ligands and Transducers on the Neurotensin Recep-tor 1 (NTS1) Conformational Ensemble
Dixon, A. D.; Inoue, A.; ROBSON, S. A.; Culhane, K.; Trinidad, J.; Sivaramakrishnan, S.; Bumbak, F.; Ziarek, J. J.
10.1101/2021.12.08.471782 — biophysics — Posted on 2021-12-10
2638 Lipid droplets 3D full measurement by holographic in-flow tomography
Pirone, D.; Sirico, D.; Miccio, L.; Bianco, V.; Mugnano, M.; Del Giudice, D.; Pasquinelli, G.; Valente, S.; Lemma, S.; Iommarini, L.; Kurelac, I.; Memmolo, P.; Ferraro, P.
10.1101/2021.12.09.471789 — biophysics — Posted on 2021-12-10
2646 Evolution of tunnels in alpha/beta-hydrolase fold proteins - what can we learn from studying epoxide hydrolases?
Bzowka, M.; Mitusinska, K.; Raczynska, A.; Skalski, T.; Samol, A.; Bagrowska, W.; Magdziarz, T.; Gora, A.
10.1101/2021.12.08.471815 — bioinformatics — Posted on 2021-12-10
2647 An engineered nanocomplex with Photodynamic and Photothermal synergistic properties for cancer treatment
Varon, E.; Blumrosen, G.; Sinvani, M.; Haimov, E.; Polani, S.; Natan, M.; Shoval, I.; Atkins, A.; Zitoun, D.; Shefi, O.
10.1101/2021.12.08.471725 — bioengineering — Posted on 2021-12-10
2648 Label-free imaging to track reprogramming of human somatic cells
Saha, K.; Skala, M. C.; Molugu, K.; Battistini, G. A.; Heaster, T.; Rouw, J.; Guzman, E. C.
10.1101/2021.12.08.471827 — bioengineering — Posted on 2021-12-10
2656 The price of defence: toxins, visual signals and oxidative state in an aposematic butterfly
Blount, J. D.; Rowland, H. M.; Mitchell, C.; Speed, M. P.; Ruxton, G. D.; Endler, J. A.; Brower, L. P.
10.1101/2021.12.08.471400 — evolutionary biology — Posted on 2021-12-10
2657 Lessons on fruiting body morphogenesis from genomes and transcriptomes of Agaricomycetes
Nagy, L. G.; Vonk, P. J.; Kunzler, M.; Foldi, C.; Viragh, M.; Ohm, R. A.; Hennicke, F.; Balint, B.; Csernetics, A.; Hegedus, B.; Hou, Z.; Liu, X.-b.; Nan, S.; Pareek, M.; Sahu, N.; Szathmari, B.; Varga, T.; Wu, H.; Yang, X.; Merenyi, Z.
10.1101/2021.12.09.471732 — evolutionary biology — Posted on 2021-12-10
2660 Trade-offs among plant reproductive traits determine interactions with floral visitors
Lanuza, J. B.; Rader, R.; Stavert, J.; Kendall, L. K.; Saunders, M. E.; Bartomeus, I.
10.1101/2021.12.09.471959 — ecology — Posted on 2021-12-10
2661 Estimating real snakebite incidence in Colombia by using mathematical modelling and statistical inference.
Bravo-Vega, C.; Renjifo-Ibanez, C.; Santos-Vega, M.; Nunez-Leon, L.; Angarita-Sierra, T.; Cordovez, J. M.
10.1101/2021.12.09.472006 — ecology — Posted on 2021-12-10
2663 The luminal AAA+ ATPase torsinA mediates distinct mechanisms of nuclear-cytoplasmic communication by adopting different functional assembly states.
Hur, K.-H.; Hennen, J. W.; Saunders, C. A.; Schoenhoefen, A.; Willey, P. T.; Morris, C. M.; Ibrahim, R. H.; Maisuria, R. S.; Mueller, J. D.; Luxton, G. W. G.
10.1101/2021.12.09.472013 — cell biology — Posted on 2021-12-10
2664 A novel Alex3/Gαq protein complex regulating mitochondrial dynamics, dendritic complexity, and neuronal survival
Izquierdo-Villalba, I.; Mirra, S.; Manso, Y.; Parcerisas, A.; Rubio, J.; Del Valle, J.; Herrero-Lorenzo, M.; Ulloa, F.; Gil-Bea, F. J.; Herrero-Lorenzo, M.; Beninca, C.; Castro-Torres, R. D.; Rebollo, E.; Marfany, G.; Auladell, C.; Navarro, X.; Enriquez, J. A.; Lopez de Munain, A.; Aragay, A. M.; Soriano, E.
10.1101/2021.12.09.471902 — cell biology — Posted on 2021-12-10
2666 HBV enveloped particle secretion is positively regulated by GRP78 through direct interaction with preS1
Shi, Y.; Jin, X.; Wu, S.; Liu, J.; Zhang, H.; Cai, X.; Yang, Y.; Zhang, X.; wei, J.; Peng, H.; Luo, M.; Zhou, H.; Zhou, H.; Huang, A.; Wang, D.
10.1101/2021.12.08.471876 — microbiology — Posted on 2021-12-10
2669 The polyanionic drug suramin neutralizes histones and prevents endotheliopathy
Villalba, N.; Sackheim, A. M.; Lawson, M. A.; Haines, L.; Chen, Y. L.; Sonkusare, S. K.; Ma, Y.-T.; Li, J.; Majumdar, D.; Bouchard, B. A.; Boyson, J. E.; Poynter, M. E.; Nelson, M. T.; Freeman, K.
10.1101/2021.12.09.469611 — immunology — Posted on 2021-12-10
2670 CD4+ and CD8+ regulatory T cells characterization in the rat using a unique transgenic Foxp3-EGFP model.
MENORET, S.; Tesson, L.; REMY, S.; Gourain, V.; Serazin, C.; Usal, C.; Guiffes, A.; Chenouard, V.; Ouisse, L.-H.; Gantier, M.; Heslan, J.-M.; Fourgeux, C.; Poschmann, J.; Guillonneau, C.; Anegon, I.
10.1101/2021.12.09.471889 — immunology — Posted on 2021-12-10
2671 SV2A-Syt1 interaction controls surface nanoclustering and access to recycling synaptic vesicles
Small, C.; Harper, C.; Kontaxi, C.; Davenport, E.; Wallis, T.; Malapaka, A.; Yak, N.; Joensuu, M.; Martinez-Marmol, R.; Cousin, M. A.; Meunier, F. A.
10.1101/2021.12.08.471864 — neuroscience — Posted on 2021-12-10
2672 Trapping of Nicotinic Acetylcholine Receptor Ligands Assayed by in vitro Cellular Studies and in vivo PET Imaging
Zhang, H.; Kao, C.-M.; Zammit, M.; Govind, A. P.; Mitchell, S.; Holderman, N.; Bhuiyan, M.; Freifelder, R.; Zhuang, X.; Mukherjee, J.; Chen, C.-T.; Green, W.
10.1101/2021.12.08.471775 — neuroscience — Posted on 2021-12-10
2673 Cylindromatosis Drives Synapse Pruning and Weakening by Promoting Macroautophagy through Akt-mTOR Signaling
Yao, W.-D.; Zajicek, A. S.; Dai, H.; Skolfield, M. C.; Phillips, H. L.; Burnette, W. J.; Javidfar, B.; Sun, S.-C.; Akbarian, S.
10.1101/2021.12.08.471792 — neuroscience — Posted on 2021-12-10
2674 Development and validation of inducible protein degradation and quantitative phosphoproteomics to identify kinase-substrate relationships.
Hards, R.; Howarth, C. L.; Wiredu, K.; LaCroix, I.; Mercado del Valle, J. C.; Adamo, M. E.; Holland, A. J.; Kettenbach, A.; Gerber, S. A.
10.1101/2021.12.08.471812 — systems biology — Posted on 2021-12-10
2681 CXCL8/CXCR2 signaling mediates bone marrow fibrosis and represents a therapeutic target in myelofibrosis
Dunbar, A.; Kim, D.; Lu, M.; Farina, M.; Yang, J. L.; Park, Y.; Gobbo, F.; Verachi, P.; Martelli, F.; Karzai, A.; Xiao, W.; Xia, L.; Elmansy, N.; Kleppe, M.; Chen, Z.; Xiao, Y.; McGovern, E.; Snyder, J.; Krishnan, A.; Hill, C.; Cordner, K.; Zouak, A.; Salama, M.; Yohai, J.; Tucker, E.; Chen, J.; Zhou, J.; McConnell, T.; Koche, R.; Rampal, R.; Migliaccio, A. R.; Fan, R.; Levine, R.; Hoffman, R.
10.1101/2021.12.08.471791 — cancer biology — Posted on 2021-12-10
2684 Long read sequencing reveals sequential complex rearrangements driven by Hepatitis B virus integration
Wang, S.; Lin, J.; Yang, X.; Li, Z.; Xu, T.; Jia, P.; Wang, T.; Wang, B.; Hu, L.; Ye, K.
10.1101/2021.12.09.471697 — genomics — Posted on 2021-12-09
2685 Ongoing transposition in cell culture reveals the phylogeny of diverse Drosophila S2 sub-lines.
Han, S.; Dias, G. B.; Basting, P. J.; Nelson, M. G.; Patel, S.; Marzo, M.; Bergman, C. M.
10.1101/2021.12.08.471819 — genomics — Posted on 2021-12-09
2689 A small molecule reveals role of insulin receptor-insulin like growth factor-1 receptor heterodimers
Simmons, K. J.; Myers, C. G.; Viswambharan, H.; Haywood, N.; Bridge, K.; Turvey, S. J.; Armstrong, T.; Lunn, L.; Meakin, P. J.; Clavane, E.; Beech, D. J.; Cubbon, R.; Wheatcroft, S. B.; McPhillie, M. J.; Fishwick, C. W.; Kearney, M. T.
10.1101/2021.12.09.471780 — cell biology — Posted on 2021-12-09
2694 The Role of Mentoring in Promoting Diversity, Equity, and Inclusion in STEM Education and Research
Marshall, A.; Vue, Z.; Palavicino-maggio, C.; Spencer, E. C.; Beasley, H. K.; Garza- Lopez, E.; Conley, Z.; Neikirk, K.; Murray, S. A.; Martinez, D.; Davis, J.; Brady, L. J.; Shuler, H. D.; Morton, D.; Hinton, A.
10.1101/2021.12.08.471502 — scientific communication and education — Posted on 2021-12-09
2696 Programmable in vivo CRISPR activation elucidates the oncogenic and immunosuppressive role of MYC in lung adenocarcinoma
Thege, F. I.; Rupani, D. N.; Bharati, B. B.; Manning, S. L.; Maitra, A.; Rhim, A. D.; Woermann, S. M.
10.1101/2021.12.09.471859 — cancer biology — Posted on 2021-12-09
2698 Mars, a molecule archive suite for reproducible analysis and reporting of single molecule properties from bioimages
Huisjes, N. M.; Retzer, T. M.; Scherr, M. J.; Agarwal, R.; Safaric, B.; Minnen, A.; Duderstadt, K. E.
10.1101/2021.11.26.470105 — biophysics — Posted on 2021-12-09
2699 eIF5B and eIF1A remodel human translation initiation complexes to mediate ribosomal subunit joining
Lapointe, C. P.; Grosely, R.; Sokabe, M.; Alvarado, C.; Wang, J.; Montabana, E.; Villa, N.; Shin, B.-S.; Dever, T. E.; Fraser, C. S.; Fernandez, I. S.; Puglisi, J. D.
10.1101/2021.12.09.471821 — biophysics — Posted on 2021-12-09
2703 Whole genome resequencing and comparative genome analysis of three Puccinia striiformis f. sp. tritici pathotypes prevalent in India
Yadav, I. S.; Bhardwaj, S. C.; Kaur, J.; Singla, D.; Kaur, S.; Kaur, H.; Rawat, N.; Tiwari, V. K.; Saunders, D.; Uauy, C.; Chhuneja, P.
10.1101/2021.12.09.471986 — bioinformatics — Posted on 2021-12-09
2706 Linked-read whole-genome sequencing resolves common and private structural variants in multiple myeloma
Pena Perez, L.; Frengen, N.; Hauenstein, J.; Gran, C.; Gustafsson, C.; Eisfeldt, J.; Kierczak, M.; Taborsak-Lines, F.; Olsen, R.-A.; Wallblom, A.; Krstic, A.; Ewels, P. A.; Lindstrand, A.; Mansson, R.
10.1101/2021.12.09.471893 — genetics — Posted on 2021-12-09
2707 Acute oral toxicity of zinc phosphide: an assessment for wild house mice in Australia
Hinds, L. A.; Henry, S.; Van de Weyer, N.; Robinson, F.; Ruscoe, W. A.; Brown, P. R.
10.1101/2021.12.09.472031 — ecology — Posted on 2021-12-09
2708 Rec8 cohesin-mediated loop-axis chromatin architecture is required for meiotic recombination
Sakuno, T.; Tashiro, S.; Tanizawa, H.; Iwasaki, O.; Ding, D.-Q.; Haraguchi, T.; Noma, K.-i.; Hiraoka, Y.
10.1101/2021.12.09.472021 — cell biology — Posted on 2021-12-09
2709 Endosomal cargo recycling mediated by Gpa1 and Phosphatidylinositol-3-Kinase is inhibited by glucose starvation
Laidlaw, K. M.; Paine, K. M.; Bisinski, D. D.; Calder, G.; Hogg, K.; Ahmed, S.; James, S.; O'Toole, P. J.; MacDonald, C.
10.1101/2021.04.02.438183 — cell biology — Posted on 2021-12-09
2710 Nanotrap Particles Improve Nanopore Sequencing of SARS-CoV-2 and Other Respiratory Viruses
Andersen, P. D.; Barksdale, S.; Barclay, R. A.; Smith, N.; Fernandes, J.; Goldfarb, D.; Barbero, R.; Jones-Roe, T.; Besse, K.; Dunlap, R.; Kelly, R.; Miao, S.; Ruhunusiri, C.; Munns, A.; Mosavi, S.; Munns, D.; Sanson, L.; Saswata, S.; Swahn, O.; Hull, K.; White, D.; Kolb, K.; Noroozi, F.; Seelam, J.; Patnaik, A.; Lepene, B.
10.1101/2021.12.08.471814 — microbiology — Posted on 2021-12-09
2711 Biogenesis of a bacterial metabolosome for propanediol utilization
Yang, M.; Wenner, N.; Dykes, G.; Li, Y.; Zhu, X.; Sun, Y.; Huang, F.; Hinton, J. C. D.; Liu, L.-N.
10.1101/2021.12.09.472018 — microbiology — Posted on 2021-12-09
2712 Nitrogen metabolism in Pseudomonas putida: functional analysis using random barcode transposon sequencing
Schmidt, M.; Pearson, A. N.; Incha, M. R.; Thompson, M. G.; Baidoo, E. E. K.; Kakumanu, R.; Mukhopadhyay, A.; Shih, P. M.; Deutschbauer, A. M.; Blank, L. M.; Keasling, J. D.
10.1101/2021.12.09.472016 — microbiology — Posted on 2021-12-09
2715 A novel bacterial protease inhibitor adjuvant in RBD-based COVID-19 vaccine formulations increases neutralizing antibodies, specific germinal center B cells and confers protection against SARS-CoV-2 infection.
Coria, L. M.; Saposnik, L. M.; Pueblas Castro, C.; Castro, E. F.; Bruno, L. A.; Stone, W. B.; Perez, P. S.; Darriba, M. L.; Chemes, L. B.; Alcain, J.; Mazzitelli, I.; Varese, A.; Salvatori, M.; Auguste, A. J.; Alvarez, D. E.; Pasquevich, K. A.; Cassataro, J.
10.1101/2021.12.07.471590 — immunology — Posted on 2021-12-09
2716 Delta breakthrough infections elicit potent, broad and durable neutralizing antibody responses
Walls, A. C.; Sprouse, K. R.; Joshi, A.; Bowen, J. E.; Franko, N.; Navarro, M.-J.; Stewart, C.; McCallum, M.; Goecker, E. A.; Degli-Angeli, E. J.; Logue, J.; Greninger, A.; Veesler, D.
10.1101/2021.12.08.471707 — immunology — Posted on 2021-12-09
2718 High-order areas and auditory cortex both represent the high-level event structure of music
Williams, J. A.; Margulis, E. H.; Nastase, S. A.; Chen, J.; Hasson, U.; Norman, K. A.; Baldassano, C. A.
10.1101/2021.01.26.428291 — neuroscience — Posted on 2021-12-09
2719 Atypus karschi Dönitz, 1887 (Araneae: Atypidae): an Asian purse-web spider established in Pennsylvania, USA
Rezac, M.; Tessler, S.; Heneberg, P.; Herrera, I. M. A.; Glorikova, N.; Forman, M.; Rezacova, V.; Kral, J.
10.1101/2021.12.09.471987 — zoology — Posted on 2021-12-09
2721 Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors
Pan, M.; Zorbas, C.; Sugaya, M.; Ishiguro, K.; Kato, M.; Nishida, M.; Zhang, H.; Candeias, M. M.; Okamoto, A.; Ishikawa, T.; Soga, T.; Aburatani, H.; Sakai, J.; Matsumura, Y.; Suzuki, T.; Proud, C. G.; Lafontaine, D. L.; Osawa, T.
10.1101/2021.12.03.471189 — cancer biology — Posted on 2021-12-09
2724 Structural mechanism for bi-directional actin crosslinking by T-plastin
Mei, L.; Reynolds, M. J.; Garbett, D.; Gong, R.; Meyer, T.; Alushin, G. M.
10.1101/2021.12.07.471696 — biophysics — Posted on 2021-12-09
2727 Ultrapotent and Broad Neutralization of SARS-CoV-2 Variants by Modular, Tetravalent, Bi-paratopic Antibodies
Miersch, S.; Saberianfar, R.; Chen, C.; Sharma, N.; Amarasinghe, G. K.; Caccuri, F.; Zani, A.; Caruso, A.; Novelli, G.; Sidhu, S. S.
10.1101/2021.11.02.466984 — bioengineering — Posted on 2021-12-09
2729 Deep Mutational Engineering of broadly-neutralizing and picomolar affinity nanobodies to accommodate SARS-CoV-1 & 2 antigenic polymorphism
Laroche, A.; Orsini Delgado, M. L.; Cuniasse, P.; Dubois, S.; Sierocki, R.; Gallais, F.; Debroas, S.; Bellanger, L.; Simon, S.; Maillere, B.; Nozach, H.
10.1101/2021.12.07.471597 — biochemistry — Posted on 2021-12-09
2730 Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike
Qu, K.; Chen, Q.; Ciazynska, K. A.; Liu, B.; Zhang, X.; Wang, J.; He, Y.; Guan, J.; He, J.; Liu, T.; Zhang, X.; Carter, A. P.; Xiong, X.; Briggs, J. A. G.
10.1101/2021.03.10.434733 — microbiology — Posted on 2021-12-09
2731 Orally administered epeleuton inhibits SARS-CoV-2 viral load, replication and pathology in the Syrian Hamster model
Climax, J.; Hamza, M.; Lafferty, A.; Guilfoyle, K.; van Amerongen, G.; Stadler, K.; Wohlsein, P.; Baumgärtner, W.; Weissbach, M.; Coughlan, D.
10.1101/2021.12.07.471588 — microbiology — Posted on 2021-12-09
2732 Combinatorial mRNA vaccination enhances protection against SARS-CoV-2 delta variant
Hajnik, R. L.; Plante, J. A.; Liang, Y.; Alameh, M.-G.; Tang, J.; Zhong, C.; Adam, A.; Scharton, D.; Rafael, G. H.; Liu, Y.; Hazell, N. C.; Sun, J.; Soong, L.; Shi, P.-Y.; Wang, T.; Sun, J.; Weissman, D.; Weaver, S. C.; Plante, K. S.; Hu, H.
10.1101/2021.12.08.471664 — microbiology — Posted on 2021-12-09
2733 B.1.1.529 escapes the majority of SARS-CoV-2 neutralizing antibodies of diverse epitopes
Cao, Y. R.; Wang, J.; Jian, F.; Xiao, T.; Song, W.; Yisimayi, A.; Huang, W.; Li, Q.; Wang, P.; An, R.; Wang, J.; Wang, Y.; Niu, X.; Yang, S.; Liang, H.; Sun, H.; Li, T.; Yu, Y.; Cui, Q.; Liu, S.; Yang, X.; Du, S.; Zhang, Z.; Hao, X.; Shao, F.; Jin, R.; Wang, X.; Xiao, J.; Wang, Y.; Xie, X. S.
10.1101/2021.12.07.470392 — immunology — Posted on 2021-12-09
2735 A dynamic clamp protocol to artificially modify cell capacitance
Pfeiffer, P.; Tomas, F. J. B.; Wu, J.; Schleimer, J.-H.; Vida, I.; Schreiber, S.
10.1101/2021.11.12.468368 — neuroscience — Posted on 2021-12-09
2736 Predictive profiling of SARS-CoV-2 variants by deep mutational learning
Taft, J. M.; Weber, C. R.; Gao, B.; Ehling, R. A.; Han, J.; Frei, L.; Metcalfe, S. W.; Yermanos, A.; Kelton, W.; Reddy, S. T.
10.1101/2021.12.07.471580 — synthetic biology — Posted on 2021-12-09
2737 The UV RESISTANCE LOCUS 8-Mediated UV-B Response Is Required Alongside CRYPTOCHROME1 For Plant Survival Under Sunlight In The Field
Stockenhuber, R.; Akiyama, R.; Tissot, N.; Yamazaki, M.; Wyler, M.; Arongaus, A. B.; Podolec, R.; Sato, Y.; Milosavljevic, S.; Widmer, A.; Ulm, R.; Shimizu, K. K.
10.1101/2021.12.08.471623 — plant biology — Posted on 2021-12-09
2740 Minimal cross-over between mutations associated with Omicron variant of SARS-CoV-2 and CD8+ T cell epitopes identified in COVID-19 convalescent individuals
Redd, A.; Nardin, A.; Kared, H.; Bloch, E. M.; Abel, B.; Pekosz, A.; Laeyendecker, O.; Fehlings, M.; Quinn, T.; Tobian, A. A.
10.1101/2021.12.06.471446 — immunology — Posted on 2021-12-09
2742 CDK9 and PP2A regulate RNA polymerase II transcription termination and coupled RNA maturation.
Tellier, M.; Zaborowska, J.; Neve, J.; Nojima, T.; Hester, S.; Furger, A.; Murphy, S.
10.1101/2021.06.21.449289 — molecular biology — Posted on 2021-12-09
2744 Latent functional connectivity underlying multiple brain states
McCormick, E. M.; Arnemann, K. L.; Ito, T.; Hanson, S. J.; Cole, M. W.
10.1101/2021.04.05.438534 — neuroscience — Posted on 2021-12-09
2745 A fungal plant pathogen overcomes conserved broad-spectrum disease resistance by rapid gene loss
Kusch, S.; Frantzeskakis, L.; Lassen, B. D.; Kümmel, F.; Pesch, L.; Barsoum, M.; Wu, H.; Walden, K. D.; Panstruga, R.
10.1101/2021.12.09.471931 — plant biology — Posted on 2021-12-09
2746 Glucose dynamics during ozone exposure measured using radiotelemetry: Stress drivers and human concordance
Henriquez, A. R.; Snow, S. J.; House, J. S.; Motsinger-Reif, A. A.; Ward-Caviness, C.; Schladweiler, M. C.; Alewel, D. I.; Miller, C. N.; Farraj, A. K.; Hazari, M. S.; Grindstaff, R.; Diaz-Sanchez, D.; Ghio, A. J.; Kodavanti, U.
10.1101/2021.12.09.471963 — pharmacology and toxicology — Posted on 2021-12-09
2747 Predicting the Functional Impact of KCNQ1 Variants with Artificial Neural Networks
Phul, S.; Kuenze, G.; Vanoye, C. G.; Sanders, C. R.; George, A. L.; Meiler, J.
10.1101/2021.12.06.471347 — biophysics — Posted on 2021-12-09
2750 The Presence of the Temporal Horn Exacerbates the Vulnerability of Hippocampus during Head Impacts
Zhou, Z.; Li, X.; Domel, A.; Dennis, E.; Georgiadis, M.; Liu, Y.; Raymond, S.; Grant, G.; Kleiven, S.; Camarillo, D.; Zeineh, M.
10.1101/2021.12.07.471634 — bioengineering — Posted on 2021-12-09
2751 Harnessing gene-gene interactions via an RNA-Sequencing network analysis framework improves precision medicine prediction in rheumatoid arthritis
Sciacca, E.; Surace, A. E. A.; Alaimo, S.; Pulvirenti, A.; Rivellese, F.; Goldmann, K.; Ferro, A.; Latora, V.; Pitzalis, C.; Lewis, M. J.
10.1101/2021.12.08.471133 — genomics — Posted on 2021-12-09
2752 Fully resolved assembly of Cryptosporidium parvum
Menon, V. K.; Okhuysen, P. C.; Chappell, C.; Mahmoud, M.; Mahmoud, M.; Meng, Q.; Vee, V.; Doddapaneni, H.; Han, Y.; Salvi, S.; Bhamidipati, S.; Kottapalli, K.; Weissenberger, G.; Shen, H.; Ross, M. C.; Hoffman, K. L.; Cregeen, S. J.; Muzny, D. M.; Metcalf, G. A.; Gibbs, R. A.; Petrosino, J. F.; Sedlazeck, F. J.
10.1101/2021.07.07.451495 — genomics — Posted on 2021-12-09
2753 Statistical Analysis of Three-Dimensional Chromatin Packing Domains Determined by Chromatin Scanning Transmission Electron Microscopy (ChromSTEM)
Li, Y.; Agrawal, V.; Virk, R. K. A.; Roth, E. W.; Li, W. S.; Eshein, A.; Frederick, J.; Huang, K.; Almassalha, L.; Bleher, R.; Carignano, M. A.; Szleifer, I. G.; Dravid, V. P.; Backman, V.
10.1101/2021.05.24.445538 — genomics — Posted on 2021-12-09
2759 BioImageIT: Open-source framework for integration of image data-management with analysis
Prigent, S.; Valades-Cruz, C. A.; Leconte, L.; Maury, L.; Salamero, J.; Kervrann, C.
10.1101/2021.12.09.471919 — bioinformatics — Posted on 2021-12-09
2764 A correlation map of genome-wide DNA methylation patterns between paired human brain and buccal samples
Sommerer, Y.; Ohlei, O.; Dobricic, V.; Oakley, D. H.; Wesse, T.; Sabet, S. S.; Demuth, I.; Franke, A.; Hyman, B. T.; Lill, C. M.; Bertram, L.
10.1101/2021.12.09.471962 — genomics — Posted on 2021-12-09
2765 Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance
Salamzade, R.; Manson, A. L.; Walker, B. J.; Brennan-Krohn, T.; Worby, C. J.; Ma, P.; He, L. L.; Shea, T. P.; Qu, J.; Chapman, S. B.; Howe, W.; Young, S. K.; Wurster, J. I.; Delaney, M. L.; Kanjilal, S.; Onderdonk, A. B.; Pironti, A.; Bittencourt, C. E.; Gussin, G. M.; Kim, D.; Peterson, E. M.; Ferraro, M. J.; Hooper, D. C.; Shenoy, E. S.; Cuomo, C. A.; Hung, D. T.; Cosimi, L. A.; Huang, S. S.; Kirby, J. E.; Pierce, V. M.; Bhattacharyya, R. P.; Earl, A. M.
10.1101/2021.12.08.471225 — genomics — Posted on 2021-12-09
2769 Wanted not, wasted not: Searching for non-target taxa in environmental DNA metabarcoding by-catch
Duarte Ritter, C.; Dal Pont, G.; Valeska Stika, P.; Horodesky, A.; Cozer, N.; Mader Netto, O. S.; Henn, C.; Ostrensky, A.; Pie, M. R.
10.1101/2021.12.08.471726 — ecology — Posted on 2021-12-09
2772 Quantitative Structural Analysis of Influenza Virus by Cryo-electron Tomography and Convolutional Neural Networks
Huang, Q. Y.; Song, K.; Xu, C.; Bolon, D.; Wang, J. P.; Finberg, R. W.; Schiffer, C. A.; Somasundaran, M.
10.1101/2021.12.09.472010 — microbiology — Posted on 2021-12-09
2773 In-depth characterization of the serum antibody epitope repertoire in inflammatory bowel disease using phage-displayed immunoprecipitation sequencing
Bourgonje, A. R.; Andreu-Sanchez, S.; Vogl, T.; Hu, S.; Vila, A. V.; Gacesa, R.; Leviatan, S.; Kurilshikov, A.; Klompus, S.; Kalka, I. N.; van Dullemen, H. M.; Weinberger, A.; Visschedijk, M. C.; Festen, E. A. M.; Faber, K. N.; Wijmenga, C.; Dijkstra, G.; Segal, E.; Fu, J.; Zhernakova, A.; Weersma, R. K.
10.1101/2021.12.07.471581 — immunology — Posted on 2021-12-09
2774 Human neural networks with sparse TDP-43 pathology reveal NPTX2 misregulation in ALS/FTLD
Hruska-Plochan, M.; Hembach, K. M.; Ronchi, S.; Wiersma, V. I.; Maniecka, Z.; Hock, E.-M.; Laferriere, F.; Sahadevan, S.; Hoop, V.; Delvendahl, I.; Panatta, M.; van der Bourg, A.; Bohaciakova, D.; Frontzek, K.; Aguzzi, A.; Lashley, T.; Robinson, M. D.; Karayannis, T.; Mueller, M.; Hierlemann, A.; Polymenidou, M.
10.1101/2021.12.08.471089 — neuroscience — Posted on 2021-12-09
2776 Early neural activity changes associated with visual conscious perception
Khalaf, A.; Kronemer, S.; Christison-Lagay, K.; Kwon, H.; Li, J.; Wu, K.; Blumenfeld, H.
10.1101/2021.12.08.471137 — neuroscience — Posted on 2021-12-09
2779 Phosphate-induced resistance to pathogen infection in Arabidopsis
Val Torregrosa, B.; Bundo, M.; Cardoso, H. M.; Pages, M. B.; Chiou, T. J.; Flors, V.; San Segundo, B.
10.1101/2021.12.09.471930 — plant biology — Posted on 2021-12-09
2786 Colonic Oxygen Microbubbles Augment Systemic Oxygenation and CO2 Removal in a Porcine Smoke Inhalation Model of Severe Hypoxia
Mountford, P. A.; Leiphrakpam, P. D.; Weber, H. R.; McCain, A.; Scribner, R. T.; Scribner, R. M.; Duarte, E. M.; Chen, J.; Borden, M. A.; Buesing, K. L.
10.1101/2021.12.08.466665 — bioengineering — Posted on 2021-12-09
2787 Spodoptera littoralis genome mining brings insights on the dynamic of expansion of gustatory receptors in polyphagous noctuidae
Meslin, C.; Mainet, P.; Montagne, N.; Robin, S.; Legeai, F.; Bretaudeau, A.; Johnston, J. S.; Koutroumpa, F.; Persyn, E.; Monsempes, C.; Francois, M.-C.; Joly, E.
10.1101/2021.12.09.471925 — genomics — Posted on 2021-12-09
2788 Co-evolution of Leptospira and Tenrecidae (Afrotheria) on Madagascar
Gomard, Y.; Goodman, S. M.; Soarimalala, V.; Turpin, M.; Lenclume, G.; Ah-Vane, M.; Golden, C. D.; Tortosa, P.
10.1101/2021.12.08.471753 — evolutionary biology — Posted on 2021-12-09
2790 Estimating abundance of a recovering transboundary brown bear population with capture-recapture models
Vanpe, C.; Piedallu, B.; Quenette, P.-Y.; Sentilles, J.; Queney, G.; Palazon, S.; Jordana, I. A.; Jato, R.; Irurtia, M. M. E.; de la Torre, J. S.; Gimenez, O.
10.1101/2021.12.08.471719 — ecology — Posted on 2021-12-09
2792 A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia
Voit, R. A.; Tao, L.; Yu, F.; Cato, L. D.; Cohen, B.; Liao, X.; Fiorini, C.; Nandakumar, S. K.; Wahlster, L.; Teichert, K.; Regev, A.; Sankaran, V. G.
10.1101/2021.12.09.471942 — cell biology — Posted on 2021-12-09
2798 Deficiency in endocannabinoid synthase DAGLB contributes to Parkinson's disease and dopaminergic neuron dysfunction
Liu, Z.; Yang, N.; Dong, J.; Tian, W.; Chang, L.; Ma, J.; Guo, J.; Tan, J.; Dong, A.; He, K.; Zhou, J.; Cinar, R.; Wu, J.; Salinas, A.; Sun, L.; Kung, J.; Xie, C.; Oldham, B.; Kumar, M.; Hawes, S.; Ding, J.; Wang, L.; Wang, T.; Chan, P.; Zhang, Z.; Le, W.; Chen, S.; Lovinger, D. M.; Cui, G.; Li, Y.; Cai, H.; Tang, B.
10.1101/2021.12.09.471983 — neuroscience — Posted on 2021-12-09
2801 Novel piece of the puzzle: ALI1 is required for oxo-C14-HSL priming in Arabidopsis
Shrestha, A.; Hernandez-Reyes, C.; Grimm, M.; Krumwiede, J.; Stein, E.; Schenk, S. T. T.; Schikora, A.
10.1101/2021.12.09.471921 — plant biology — Posted on 2021-12-09
2807 Manganese is a Physiologically Relevant TORC1 Activator in Yeast and Mammals.
Nicastro, R.; Gaillard, H.; Zarzuela, L.; Fernandez-Garcia, E.; Tome, M.; Garcia-Rodriguez, N.; Peli-Gulli, M.-P.; Duran, R. V.; De Virgilio, C.; Wellinger, R. E.
10.1101/2021.12.09.471923 — cell biology — Posted on 2021-12-09
2808 Escape Steering by Cholecystokinin Peptidergic Signaling
Chen, L.; Liu, Y.; Su, P.; Hung, W.; Li, H.; Wang, Y.; Yue, Z.; Ge, M.; Wu, Z.; Zhang, Y.; Fei, P.; Chen, L.-M.; Tao, L.; Mao, H.; Zhen, M.; Gao, S.
10.1101/2021.12.08.471862 — neuroscience — Posted on 2021-12-09
2810 Drosulfakinin signaling modulates female sexual receptivity in Drosophila
Zhou, C.; Wang, T.; Jing, B.; Deng, B.; Shi, K.; Li, J.; Ma, B.; Wu, F.
10.1101/2021.12.09.471924 — neuroscience — Posted on 2021-12-09
2811 Quantitative multidimensional phenotypes improve genetic analysis of laterality traits
Schmitz, J.; Zheng, M.; Lui, K. F. H.; McBride, C.; Ho, C. S.- H.; Paracchini, S.
10.1101/2021.04.28.441754 — genetics — Posted on 2021-12-09
2813 Role of anterior insula cortex in context-induced relapse of nicotine-seeking
Ghareh, H.; Alonso-Lozares, I.; Schetters, D.; Herman, R. J.; Heistek, T. S.; Van Mourik, Y.; Jean-Richard-dit-Bressel, P.; Zernig, G.; Mansvelder, H. D.; De Vries, T. J.; Marchant, N. J.
10.1101/2021.12.08.471717 — neuroscience — Posted on 2021-12-09
2814 Neurexins in serotonergic neurons regulate serotonin transmission and complex mouse behaviors
Cheung, A.; Matsui, A.; Abe, M.; Sakimura, K.; Sasaoka, T.; Uemura, T.; Imamura Kawasawa, Y.; Futai, K.
10.1101/2021.12.09.471904 — neuroscience — Posted on 2021-12-09
2815 Stress-impaired reward pathway promotes distinct feeding behavior patterns
Fujioka, Y.; Kawai, K.; Endo, K.; Ishibashi, M.; Iwade, N.; Tuerde, D.; Kaibuchi, K.; Yamashita, T.; Yamanaka, A.; Katsuno, M.; Watanabe, H.; Ishigaki, S.; Sobue, G.
10.1101/2021.12.08.471524 — neuroscience — Posted on 2021-12-09
2816 EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma
Voeltzke, K.; Scharov, K.; Funk, C.; Kahler, A.; Picard, D.; Hauffe, L.; Orth, M. F.; Remke, M.; Esposito, I.; Kirchner, T.; Schramm, A.; Rotblat, B.; Gruenewald, T. G. P.; Reifenberger, G.; Leprivier, G.
10.1101/2021.12.08.471784 — cancer biology — Posted on 2021-12-09
2817 Long Noncoding RNA RROL Provides Chromatin Scaffold for MYC-WDR82 Interaction to Impact Lipid Metabolism and Tumor Cell Growth in Multiple Myeloma
Morelli, E.; Fulciniti, M.; Samur, M. K.; Ribeiro, C. F.; Wert-Lamas, L.; Henninger, J. E.; Gulla, A.; Aktas-Samur, A.; Todoerti, K.; Talluri, S.; Park, W. D.; Federico, C.; Scionti, F.; Amodio, N.; Bianchi, G.; Johnstone, M.; Liu, N.; Gramegna, D.; Russo, N. A.; Lin, C.; Tai, Y.-T.; Neri, A.; Chauhan, D.; Hideshima, T.; Shammas, M.; Tassone, P.; Gryaznov, S.; Young, R.; Anderson, K. C.; Novina, C.; Loda, M.; Munshi, N. C.
10.1101/2021.12.08.471297 — cancer biology — Posted on 2021-12-09
2820 Structural basis for substrate recognition, ligation and activation by a hyperactive Asn peptide ligase from Viola yedoensis
Lescar, J.; Hu, S.; El Sahili, A.; Kishore, S.; Hemu, X.; Liu, C. F.; Tam, J. P.; Goh, B. C.; Wong, Y. H.; Wang, Z.
10.1101/2021.12.09.471967 — biochemistry — Posted on 2021-12-09
2821 Genomic adaptation of the picoeukaryote Pelagomonas calceolata to temperate iron-poor oceans revealed by a chromosome-scale genome sequence.
Guerin, N.; Ciccarella, M.; Flamant, E.; Fremont, P.; Mangenot, S.; Istace, B.; Noel, B.; Romac, S.; Bachy, C.; Gachenot, M.; Pelletier, E.; Alberti, A.; Jaillon, O.; Cruaud, C.; Wincker, P.; Aury, J.-M.; Carradec, Q.
10.1101/2021.10.25.465678 — genomics — Posted on 2021-12-09
2822 Supergenes origin and maintenance in Atlantic cod
Matschiner, M.; Barth, J. M. I.; Torresen, O. K.; Star, B.; Baalsrud, H. T.; Brieuc, M. S. O.; Pampoulie, C.; Bradbury, I.; Jakobsen, K. S.; Jentoft, S.
10.1101/2021.02.28.433253 — evolutionary biology — Posted on 2021-12-09
2823 The p97-UBXD8 complex modulates ER-Mitochondria contact sites by modulating membrane lipid saturation and composition
Ganji, R.; Paulo, J.; Xi, Y.; Kline, I.; Zhu, J.; Clemen, C. S.; Weihl, C. C.; Purdy, J. G.; Gygi, S.; Raman, M.
10.1101/2021.12.08.471763 — cell biology — Posted on 2021-12-09
2824 Interplay Between KRAS and LZTR1 Protein Turnover, Controlled by CUL3/LZTR1 E3 Ubiquitin Ligase, is Disrupted by KRAS Mutations
Damianou, A.; Liang, Z.; Lassen, F.; Vere, G.; Hester, S.; Charles, P.; Pinto-Fernandez, A.; Santos-Delgado, A.; Fisher, R.; Kessler, B. M.
10.1101/2021.11.23.469679 — molecular biology — Posted on 2021-12-09
2830 Sentinel2GlobalLULC: A deep-learning-ready Sentinel-2 RGB image dataset for global land use/cover mapping
Benhammou, Y.; Alcaraz-Segura, D.; Guirado, E.; Khaldi, R.; Achchab, B.; Herrera, F.; Tabik, S.
10.1101/2021.12.01.470768 — ecology — Posted on 2021-12-09
2831 Reconstructed signaling and regulatory networks identify potential drugs for SARS-CoV-2 infection
Ding, J.; Lugo-Martinez, J.; Yuan, Y.; Huang, J.; Hume, A. J.; Suder, E. L.; Muhlberger, E.; Kotton, D. N.; Bar-Joseph, Z.
10.1101/2020.06.01.127589 — systems biology — Posted on 2021-12-09
2832 Novel Fusarium Wilt Resistance Genes Uncovered in the Wild Progenitors and Heirloom Cultivars of Strawberry
Pincot, D. D. A.; Feldmann, M. J.; Hardigan, M. A.; Vachev, M. V.; Henry, P. M.; Gordon, T. R.; Rodriguez, A.; Cobo, N.; Cole, G. S.; Coaker, G. L.; Knapp, S. J.
10.1101/2021.12.07.471687 — plant biology — Posted on 2021-12-09
2833 The eukaryotic translation initiation factor eIF4E reprogrammes the splicing machinery anddrives alternative splicing
Ghram, M.; Morris, G.; Culjkovic-Kraljacic, B.; Gendron, P.; Skrabanek, L.; Revuelta, M. V.; Cerchietti, L.; Guzman, M.; Borden, K.
10.1101/2021.12.07.471666 — cancer biology — Posted on 2021-12-09
2834 Structural mechanism for bi-directional actin crosslinking by T-plastin
Mei, L.; Reynolds, M. J.; Garbett, D.; Gong, R.; Meyer, T.; Alushin, G. M.
10.1101/2021.12.07.471696 — biophysics — Posted on 2021-12-09
2837 Severe disturbance overflows the stabilizing buffer of variable biotic interactions
Hashimoto, K.; Hayasaka, D.; Eguchi, Y.; Seko, Y.; Cai, J.; Goka, K.; Kadoya, T.
10.1101/2021.12.07.471695 — ecology — Posted on 2021-12-09
2840 High-Speed Low-Light In Vivo Two-Photon Voltage Imaging of Large Neuronal Populations
Platisa, J.; Ye, X.; Ahrens, A. M.; Liu, C.; Chen, I. A.; Davison, I. G.; Tian, L.; Pieribone, V. A.; Chen, J. L.
10.1101/2021.12.07.471668 — neuroscience — Posted on 2021-12-09
2841 Reconfigurations in brain networks upon awakening from slow wave sleep: Interventions and implications in neural communication
Hilditch, C. J.; Bansal, K.; Chachad, R.; Wong, L. R.; Bathurst, N. G.; Feick, N. H.; Santamaria, A.; Shattuck, N. L.; Garcia, J. O.; Flynn-Evans, E. E.
10.1101/2021.12.07.471633 — neuroscience — Posted on 2021-12-09
2842 Early stage differentiation of glia in human and mice.
Frazel, P.; Labib, D.; Brosh, R.; Fossati, V.; Boeke, J. D.; Liddelow, S. A.
10.1101/2021.12.07.471509 — neuroscience — Posted on 2021-12-09
2843 Recut: a Concurrent Framework for Sparse Reconstruction of Neuronal Morphology
Marrett, K.; Zhu, M.; Chi, Y.; Chen, Z.; Choi, C.; Dong, H.-W.; Park, C. S.; Cong, J.; Yang, X. W.
10.1101/2021.12.07.471686 — neuroscience — Posted on 2021-12-09
2845 Physiological activation of the nephron central command drives endogenous kidney tissue regeneration
Gyarmati, G.; Shroff, U. N.; Riquier-Brison, A.; Desposito, D.; Ju, W.; Izuhara, A.; Deepak, S.; Burford, J.; Kadoya, H.; Chen, Y.; Rinschen, M.; Ahmadi, N.; Lau, L.; Gill, I.; Kretzler, M.; Peti-Peterdi, J.
10.1101/2021.12.07.471692 — physiology — Posted on 2021-12-09
2848 Scalable Adaptive Protein Ensemble Refinement Integrating Flexible Fitting
Sarkar, D.; Lee, H.; Vant, J. W.; Turilli, M.; Jha, S.; Singharoy, A.
10.1101/2021.12.07.471672 — biophysics — Posted on 2021-12-09
2849 Differential Histone-DNA Interactions Dictate Nucleosome Recognition of the Pioneer Transcription Factor Sox
Ozden, B.; Boopathi, R.; Barlas, A. B.; Lone, I. N.; Bednar, J.; Petosa, C.; Kale, S.; Hamiche, A.; Angelov, D.; Dimitrov, S.; Karaca, E.
10.1101/2021.12.07.471700 — biophysics — Posted on 2021-12-09
2856 Spatiotemporal transcriptomics reveals pathogenesis of viral myocarditis
Mantri, M.; Hinchman, M. M.; McKellar, D. W.; Wang, M. F. Z.; Cross, S. T.; Parker, J. S. L.; De Vlaminck, I.
10.1101/2021.12.07.471659 — genomics — Posted on 2021-12-09
2860 Early detection of sublexical and lexical processing in beginning readers: evidence from Steady-State Visual Evoked Potentials (SSVEPs)
Wang, F.; Nguyen, Q. T. H.; Kaneshiro, B.; Hasak, L.; Wang, A. M.; Toomarian, E. Y.; Norcia, A. M.; McCandliss, B.
10.1101/2021.12.07.471641 — neuroscience — Posted on 2021-12-09
2862 Intermittent brain network reconfigurations and the resistance to social media influence
Lima Dias Pinto, I. I.; Rungratsameetaweemana, N.; Flaherty, K.; Periyannan, A.; Meghdadi, A.; Richard, C.; Berka, C.; Bansal, K.; Omar Garcia, J.
10.1101/2021.12.07.471625 — neuroscience — Posted on 2021-12-09
2863 Neural Oscillatory Characteristics of Feedback Associated Activity in Globus Pallidus Interna
Choubdar, H.; Mahdavi, M.; Rostami, Z.; Zabeh, E.; Gillies, M. J.; Green, A. L.; Aziz, T.; Lashgari, R.
10.1101/2021.12.07.471662 — neuroscience — Posted on 2021-12-09
2866 Small transcriptional differences lead to distinct NF-κB dynamics in quasi-identical cells
Kizilirmak, C.; Monteleone, E.; Garcia-Manteiga, J. M.; Brambilla, F.; Agresti, A.; Bianchi, M. E.; Zambrano, S.
10.1101/2021.12.07.471485 — systems biology — Posted on 2021-12-09
2868 Semi-automated computational assessment of cancer organoid viability using rapid live-cell microscopy
Buehler, J. D.; Bird, C. E.; Savani, M. R.; Gattie, L. C.; Hicks, W. H.; Levitt, M. M.; El Shami, M.; Hatanpaa, K. J.; Richardson, T. E.; McBrayer, S. K.; Abdullah, K. G.
10.1101/2021.12.07.471003 — bioinformatics — Posted on 2021-12-09
2870 HSV-1 and influenza infection induce linear and circular splicing of the long NEAT1 isoform
Friedl, M.-S.; Djakovic, L.; Kluge, M.; Hennig, T.; Whisnant, A. W.; Backes, S.; Doelken, L.; Friedel, C. C.
10.1101/2021.12.07.471605 — bioinformatics — Posted on 2021-12-09
2871 Computationally defined and in vitro validated putative genomic safe harbour loci for transgene expression in human cells
Autio, M. I.; Motakis, E.; Perrin, A.; Bin Amin, T.; Tiang, Z.; Do, D. V.; Wang, J.; Tan, J.; Tan, W. X.; Teo, A. K. K.; Foo, R.
10.1101/2021.12.07.471422 — bioengineering — Posted on 2021-12-09
2874 Single cell quantification of ribosome occupancy in early mouse development
Tonn, T.; Ozadam, H.; Han, C.; Segura, A.; Tran, D.; Catoe, D.; Salit, M.; Cenik, C.
10.1101/2021.12.07.471408 — developmental biology — Posted on 2021-12-09
2876 Vascular proteome responses precede organ dysfunction in sepsis
Sorrentino, J. T.; Golden, G. J.; Morris, C.; Painter, C.; Nizet, V.; Campos, A. R.; Smith, J. W.; Karlsson, C. A. Q.; Malmström, J.; Lewis, N. E.; Esko, J. D.; Gomez Toledo, A.
10.1101/2021.12.07.471579 — immunology — Posted on 2021-12-09
2877 Endogenous Syngap1 Alpha Splice Forms Promote Cognitive Function and Seizure Protection
Kilinc, M.; Rumbaugh, G.; Miller, C. A.; Lynch, G.; Coba, M.; Bayes, A.; Araki, Y.; Gou, G.; Reich, A.; Graham, N.; Hartel, N.; Wilkinson, B.; Lauterborn, J.; Le, A.; Rojas, C.; Creson, T. K.; Arora, V.
10.1101/2021.12.05.471306 — neuroscience — Posted on 2021-12-09
2878 The Spatial Reach of Neuronal Coherence and Spike-field Coupling across the Human Neocortex
Myers, J.; Smith, E. H.; Leszczynski, M.; O'Sullivan, J.; McKhann, G. M.; Mesgarani, N.; Schroeder, C.; Schevon, C.; Sheth, S.
10.1101/2021.12.07.471617 — neuroscience — Posted on 2021-12-09
2879 Heterogeneity of the GFP fitness landscape and data-driven protein design
Gonzalez Somermeyer, L.; Fleiss, A.; Mishin, A. S.; Bozhanova, N. G.; Igolkina, A. A.; Meiler, J.; Alaball Pujol, M.-E.; Putintseva, E. V.; Sarkisyan, K. S.; Kondrashov, F.
10.1101/2021.12.08.471728 — synthetic biology — Posted on 2021-12-09
2881 Cryo-EM structure of an amyloid fibril formed by full-length human SOD1 reveals its pathological conformational conversion
Wang, L.-Q.; Ma, Y.; Yuan, H.-Y.; Zhao, K.; Zhang, M.-Y.; Wang, Q.; Huang, X.; Xu, W.-C.; Chen, J.; Li, D.; Zhang, D.; Zou, L.; Yin, P.; Liu, C.; Liang, Y.
10.1101/2021.12.07.471532 — biochemistry — Posted on 2021-12-09
2883 Microdomain protein Nce102 is a local sensor of plasma membrane sphingolipid balance
Zahumensky, J.; Fernandes, C. M.; Vesela, P.; Del Poeta, M.; Konopka, J. B.; Malinsky, J.
10.1101/2021.12.06.471370 — cell biology — Posted on 2021-12-09
2884 TSG101 Associates with PARP1 and is Essential for PARylation and DNA Damage-induced NF-κB Activation
Tufan, A. B.; Lazarow, K.; Kolesnichenko, M.; Sporbert, A.; von Kries, J. P.; Scheidereit, C.
10.1101/2021.12.07.471537 — molecular biology — Posted on 2021-12-09
2885 SARS-CoV-2 variants of concern are dependent on IFITM2 for efficient replication in human lung cells
Nchioua, R.; Schundner, A.; Kmiec, D.; Prelli Bozzo, C.; Zech, F.; Koepke, L.; Graf, A.; Krebs, S.; Blum, H.; Frick, M.; Sparrer, K. M. J.; Kirchhoff, F.
10.1101/2021.12.06.471527 — immunology — Posted on 2021-12-09
2886 Gene therapy targeting the blood-brain barrier improves neurological symptoms in a model of genetic MCT8 deficiency
Sundaram, S. M.; Arrulo Pereira, A.; Köpke, H.; Müller-Fielitz, H.; Angelis, M. D.; Müller, T. D.; Heuer, H.; Körbelin, J.; Krohn, M.; Mittag, J.; Nogueiras, R.; Prevot, V.; Schwaninger, M.
10.1101/2021.12.05.471343 — neuroscience — Posted on 2021-12-09
2887 XopQ induced stromule formation in Nicotiana benthamiana is causally linked to ETI signaling and depends on ADR1 and NRG1
Prautsch, J.; Erickson, J. L.; Özyürek, S.; Gormannns, R.; Franke, L.; Parker, J. E.; Stuttmann, J.; Schattat, M. H.
10.1101/2021.12.06.471425 — plant biology — Posted on 2021-12-09
2888 I-M-150847, a novel GLP-1 and GIP receptor dual agonist, reduces body weight gain and improves glycemic control in the rodent model of type 2 diabetes and obesity.
MITRA, P.; Bauri, R.; Bele, S.; Edelli, J.; Dasadhikari, S.; Reddy, N. C.; Kurukuti, S.; Garai, K.; Devasia, T.; Ibrahim, A.; Rai, V.
10.1101/2021.12.05.471325 — physiology — Posted on 2021-12-09
2892 Oxylipin metabolism is controlled by mitochondrial b-oxidation during bacterial inflammation.
Misheva, M.; Kotzamanis, K.; Davies, L.; Tyrrell, V.; Rodrigues, P.; Benavides, G.; Christine, H.; Murphy, R.; Kennedy, P.; Taylor, P.; Rosas, M.; Jones, S.; McLaren, J.; Deshpande, S.; Andrews, R.; Schebb, N. H.; Czubala, M.; Gurney, M.; Aldrovandi, M.; Meckelmann, S.; Ghazal, P.; Darley-Usmar, V.; White, D.; O'Donnell, V.
10.1101/2020.08.17.252007 — biochemistry — Posted on 2021-12-09
2895 STRAIGHT-IN: A platform for high-throughput targeting of large DNA payloads into human pluripotent stem cells
Grandela, C.; Blanch-Asensio, A.; Brandao, K. O.; de Korte, T.; Yiangou, L.; Mol, M. P. H.; van Meer, B. J.; Mummery, C. L.; Davis, R. P.
10.1101/2021.12.08.471715 — cell biology — Posted on 2021-12-09
2896 C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100A8 and S100A9
Jauch-Speer, S.-L.; Wolf, J.; Herrera-Rivero, M.; Martens, L.; Imam Chasan, A.; Witten, A.; Markus, B.; Schieffer, B.; Vogl, T.; Stoll, M.; Roth, J.; Fehler, O.
10.1101/2021.12.05.471309 — cell biology — Posted on 2021-12-09
2897 Quantitative Mapping of Keratin Networks in 3D
Windoffer, R.; Schwarz, N.; Yoon, S.; Piskova, T.; Scholkemper, M.; Stegmaier, J.; Bönsch, A.; Di Russo, J.; Leube, R.
10.1101/2021.12.06.470977 — cell biology — Posted on 2021-12-09
2898 Wide Diversity of Recombinant Noroviruses Circulating in Spain, 2016 to 2020
Navarro-Lleo, N.; Santiso-Bellon, C.; Vila-Vicent, S.; Carmona-Vicente, N.; Gozalbo-Rovira, R.; Rodriguez-Diaz, J.; Buesa, J.
10.1101/2021.12.02.471049 — microbiology — Posted on 2021-12-09
2900 Analyses of the Autism-associated Neuroligin-3 R451C Mutation in Human Neurons Reveals a Gain-of-Function Synaptic Mechanism
Wang, L.; Mirabella, V. R.; Dai, R.; Su, X.; Xu, R.; Jadali, A.; Bernabucci, M.; Singh, I.; Chen, Y.; Tian, J.; Jiang, P.; Kwan, K.; Pak, C.; LIU, C.; Comoletti, D.; Hart, R. P.; Chen, C.; Sudhof, T. C.; Pang, Z. P.
10.1101/2021.12.07.471501 — neuroscience — Posted on 2021-12-09
2901 Pre-determined diversity in resistant fates emerges from homogenous cells after anti-cancer drug treatment
Goyal, Y.; Dardani, I. P.; Busch, G. T.; Emert, B.; Fingerman, D.; Kaur, A.; Jain, N.; Mellis, I. A.; Li, J.; Kiani, K.; Fane, M. E.; Weeraratna, A. T.; Herlyn, M.; Raj, A.
10.1101/2021.12.08.471833 — systems biology — Posted on 2021-12-09
2902 Root membrane ubiquitinome under short-term osmotic stress
Berger, N.; Demolombe, V.; Hem, S.; Rofidal, V.; Steinmann, L.; Krouk, G.; Crabos, A.; Nacry, P.; Verdoucq, L.; Santoni, V.
10.1101/2021.12.06.471398 — plant biology — Posted on 2021-12-09
2903 Glioblastoma embryonic-like stem cells exhibit immune-evasive phenotype
Sese, B.; Iniguez, S.; Ensenat, M. A.; Llinas, P.; Ramis, G.; Orozco, J. I. J.; Villalonga, P.; Fernandez, S.; Marzese, D.
10.1101/2021.12.07.471556 — cancer biology — Posted on 2021-12-09
2904 Molecular mechanism of claudin-15 strand flexibility
Fuladi, S.; McGuinness, S.; Shen, L.; Weber, C. R.; Khalili-Araghi, F.
10.1101/2021.12.07.471660 — biophysics — Posted on 2021-12-09
2908 Rac1 signaling in microglia is essential for synaptic proteome plasticity and experience-dependent cognitive performance
Socodato, R.; Almeida, T. O.; Portugal, C. C.; Santos, E. C. S.; Tedim-Moreira, J.; Canedo, T.; Baptista, F.; Magalhaes, A.; Ambrosio, A. F.; Brakebusch, C.; Rubinstein, B.; Moreira, I.; Summavielle, T.; Pinto, I. M.; Relvas, J. B.
10.1101/2021.10.18.464802 — neuroscience — Posted on 2021-12-09
2912 ACTIN Anchors the Highly Oligomeric DRP1 at Mitochondria-Sarcoplasmic Reticulum Contact Sites in Adult Murine Heart: Its Functional Implication
Fernandez-Sanz, C.; De la Fuente Perez, S.; Nichtova, Z.; Yuan, Y.; Lanvermann, S.; Tsai, H.-Y.; Ferderico, M.; Xin, Y.; Csordas, G.; Wang, W.; Mourier, A.; Sheu, S.-S.
10.1101/2021.11.29.470468 — physiology — Posted on 2021-12-09
2913 Cell-type specific circadian bioluminescence rhythms in Dbp reporter mice
Smith, C. B.; van der Vinne, V.; McCartney, E.; Stowie, A. C.; Leise, T. L.; Martin-Burgos, B.; Molyneux, P. C.; Garbutt, L. A.; Brodsky, M. H.; Davidson, A. J.; Harrington, M. E.; Dallmann, R.; Weaver, D. R.
10.1101/2021.04.04.438413 — physiology — Posted on 2021-12-09
2922 Biophysical Characterisation of Human LincRNA-p21 Sense and Antisense Alu Inverted Repeats
D'Souza, M.; Mrozowich, T.; Badmalia, M. D.; Geeraert, M.; Frederickson, A.; Henrickson, A.; Demeler, B.; Wolfinger, M. T.; Patel, T. R.
10.1101/2021.12.08.471813 — biochemistry — Posted on 2021-12-08
2923 Transcriptomic modulation in response to an intoxication with deltamethrin in Triatoma infestans, vector of Chagas disease
Traverso, L.; Latorre Estivalis, J. M.; da Rocha Fernandes, G.; Fronza, G.; Lobbia, P.; Mougabure Cueto, G.; Ons, S.
10.1101/2021.12.08.471710 — genomics — Posted on 2021-12-08
2924 Genomic ancestry, diet and microbiomes of Upper Palaeolithic hunter-gatherers from San Teodoro cave (Sicily, Italy)
Scorrano, G.; Nielsen, S. H.; Lo Vetro, D.; Mackie, M.; Margaryan, A.; Fotakis, A. K.; Martinez-Labarga, C.; Fabbri, P. F.; Allentoft, M. E.; Carra, M.; Martini, F.; Rickards, O.; Olsen, J. V.; Cappellini, E.; Sikora, M.
10.1101/2021.12.08.471745 — genetics — Posted on 2021-12-08
2925 The p97-UBXD8 complex modulates ER-Mitochondria contact sites by modulating membrane lipid saturation and composition
Raman, M.; Ganji, R.; Paulo, J.; Xi, Y.; Kline, I.; Zhu, J.; Clemen, C. S.; Weihl, C. C.; Purdy, J. G.; Gygi, s.
10.1101/2021.12.08.471763 — cell biology — Posted on 2021-12-08
2928 Ribosome changes elicit non-canonical translation for chemosurvival in G0 leukemic cells
Datta, C.; Truesdell, S. S.; Bukhari, S. I.; Ngue, H.; Buchanan, B.; Wu, K. Q.; Le Tonqueze, O.; Lee, S.; Granovetter, M.; Boukhali, M.; Kreuzer, J.; Haas, W.; Vasudevan, S.
10.1101/2021.12.07.471635 — molecular biology — Posted on 2021-12-08
2929 Rational engineering of industrial S. cerevisiae: towards xylitol production from sugarcane bagasse
de Mello, F. d. S. B.; Maneira, C.; Lizarazo, F. U. S.; Nagamatsu, S.; Vargas, B. d. O.; Vieira, C.; Secches, T.; Coradini, A. L. V.; Silvello, M. A.; Goldbeck, R.; Pereira, G. G. A.; Teixeira, G. S.
10.1101/2021.12.08.471450 — molecular biology — Posted on 2021-12-08
2935 No evidence of fetal defects or anti-syncytin-1 antibody induction following COVID-19 mRNA vaccination
Lu-Culligan, A.; Tabachnikova, A.; Tokuyama, M.; Lee, H. J.; Lucas, C.; Silva Monteiro, V.; Muenker, M. C.; Mohanty, S.; Huang, J.; Kang, I.; Dela Cruz, C.; Farhadian, S.; Campbell, M.; Yildirim, I.; Shaw, A.; Ko, A.; Omer, S.; Iwasaki, A.
10.1101/2021.12.07.471539 — immunology — Posted on 2021-12-08
2936 An effective workshop on How to be an Effective Mentor for Underrepresented STEM Trainees
Marshall, A.; Vue, Z.; Palavicino-Maggio, C.; Spencer, E. C.; Beasley, H. K.; Garza Lopez, E.; Conley, Z.; Neikirk, K.; Murray, S. A.; Martinez, D.; Davis, J.; Brady, L.; Shuler, H. D.; Morton, D.; Hinton, A.
10.1101/2021.12.06.471498 — scientific communication and education — Posted on 2021-12-08
2938 Structural insights into distinct signaling profiles of the μOR activated by diverse agonists
Qu, Q.; Huang, W.; Aydin, D.; Paggi, J. M.; Seven, A. B.; Wang, H.; Chakraborty, S.; Che, T.; DiBerto, J. F.; Robertson, M. J.; Inoue, A.; Roth, B. L.; Majumdar, S.; Dror, R. O.; Kobilka, B. K.; Skiniotis, G.
10.1101/2021.12.07.471645 — biophysics — Posted on 2021-12-08
2943 Production of novel Spike truncations in Chinese hamster ovary cells
Minami, S. A.; Jung, S.; Huang, Y.; Harris, B. S.; Kenaston, M. W.; Faller, R.; Nandi, S.; McDonald, K. A.; Shah, P. S.
10.1101/2021.12.06.471489 — bioengineering — Posted on 2021-12-08
2945 Structural basis for topological regulation of Tn3 resolvase
Montano, S. P.; Rowland, S.-J.; Fuller, J. R.; Burke, M. E.; MacDonald, A. I.; Boocock, M. R.; Stark, W. M.; Rice, P. A.
10.1101/2021.12.07.471667 — biochemistry — Posted on 2021-12-08
2950 Characterization of the interaction between SARS-CoV-2 Membrane Protein and Proliferating Cell Nuclear Antigen (PCNA) as a Potential Therapeutic Target
Zambalde, E. P.; Mancini, M. C. S.; Scudero, O. B.; Pavan, I. C. B.; Severi, M. B.; Morelli, A. P.; Amorim, M. R.; dos Santos, K. B.; Parise, P. L.; Gois, M. M.; Toledo-Teixeira, D. A.; Mauad, T.; Saldiva, P. H. N.; Dolhnikoff, M.; Proenca-Modena, J. L.; Marques-Souza, H.; Ventura, A. M.; Simabuco, F. M.
10.1101/2021.12.06.471464 — molecular biology — Posted on 2021-12-08
2952 The cellular characterisation of SARS-CoV-2 spike protein in virus-infected cells using Receptor Binding Domain-binding specific human monoclonal antibodies.
Chan, C. E.-Z.; Ng, C.-G.; Lim, A. P. C.; Seah, S. G.-K.; Chye, D. H.; Wong, S. K. K.; Lim, J.-H.; Lim, V. Z.-Y.; Lai, S. K.; Wong, P.-S.; Leong, K.-M.; Liu, Y.; Sugrue, R.; Tan, B. H.
10.1101/2021.12.06.471528 — microbiology — Posted on 2021-12-08
2953 Kasturi Haldar, Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism, lipid transport and oxidative stress response
Alpizar-Sosa, E. A.; Binti Ithnin, N. R.; Wei, W.; Pountain, A. W.; Weidt, S. K.; Donachie, A. M.; Ritchie, R.; Dickie, E. A.; Burchmore, R. J. S.; Denny, P. W.; Barrett, M. P.
10.1101/2021.12.08.471712 — microbiology — Posted on 2021-12-08
2955 Metabolic dysregulation induces impaired lymphocyte memory formation during severe SARS-CoV-2 infection
Nguyen, H.; Gurshaney, S.; Alvarez, A. M.; Ezhakunnel, K.; Manalo, A.; Huynh, T.-H.; Le, N. -T.; Lupu, D.; Gardell, S.
10.1101/2021.12.06.471421 — immunology — Posted on 2021-12-08
2956 An exploratory study of EEG connectivity during the first year of life in preterm and full-term infants
Gonzalez-Moreira, E.; Paz-Linares, D.; Cubero-Rego, L.; Areces-Gonzalez, A.; Fernandez, T.; Hinojosa-Rodriguez, M.; Valdes-Sosa, P. A.; Harmony, T.
10.1101/2021.11.24.469864 — neuroscience — Posted on 2021-12-08
2961 Opposing steroid signals modulate protein homeostasis through deep changes in fat metabolism in Caenorhabditis elegans
Gomez Escribano, A. P.; Mora-Martinez, C.; Roca, M.; Walker, D.; Panadero, J.; Sequedo, M. D.; Saini, R.; Knoelker, H.-J.; Blanca, J. M.; Burguera, J. A.; Lahoz, A.; Canizares, J.; Millan, J. M.; Burton, N.; Schafer, W.; Vazquez-Manrique, R.
10.1101/551580 — genetics — Posted on 2021-12-08
2963 HSFs drive stress type-specific transcription of genes and enhancers
Himanen, S. V.; Puustinen, M. C.; Da Silva, A. J.; Vihervaara, A.; Sistonen, L.
10.1101/2021.11.23.469701 — molecular biology — Posted on 2021-12-08
2964 Marburg and Ebola virus infections elicit a complex, muted inflammatory state in bats
Jayaprakash, A. D.; Ronk, A. J.; Prasad, A. N.; Covington, M. F.; Stein, K. R.; Schwarz, T. M.; Hekmaty, S.; Fenton, K. A.; Geisbert, T. W.; Basler, C. F.; Bukreyev, A.; Sachidanandam, R.
10.1101/2020.04.13.039503 — microbiology — Posted on 2021-12-08
2966 Lytic transglycosylases mitigate periplasmic crowding by degrading soluble cell wall turnover products
Weaver, A. I.; Alvarez, L.; Rosch, K. M.; Ahmed, A.; Wang, G. S.; VanNieuwenzhe, M. S.; Cava, F.; Doerr, T.
10.1101/2021.07.27.453986 — microbiology — Posted on 2021-12-08
2969 Functional expression of opioid receptors and other human GPCRs in yeast engineered to produce human sterols
Bean, B. D.; Mulvihill, C.; Garge, R. K.; Boutz, D. R.; Rousseau, O.; Floyd, B. M.; Cheney, W.; Gardner, E. C.; Ellington, A. D.; Marcotte, E. M.; Gollihar, J. D.; Whiteway, M.; Martin, V. J.
10.1101/2021.05.12.443385 — synthetic biology — Posted on 2021-12-08
2971 Tsc1 haploinsufficiency leads to Pax2 dysregulation in the developing murine cerebellum
Serra, I.; Stravs, A.; Osorio, C.; Oyaga, M. R.; Schonewille, M.; Tudorache, C.; Badura, A.
10.1101/2021.12.08.471768 — neuroscience — Posted on 2021-12-08
2972 Effect sizes of causal variants for gene expression and complex traits differ between populations
Patel, R. A.; Musharoff, S. A.; Spence, J. P.; Pimentel, H.; Tcheandjieu, C.; Mostafavi, H.; Sinnott-Armstrong, N.; Clarke, S. L.; Smith, C. J.; VA Million Veteran Program, ; Durda, P. P.; Taylor, K. D.; Tracy, R.; Liu, Y.; Johnson, C. W.; Aguet, F.; Ardlie, K. G.; Gabriel, S.; Smith, J.; Nickerson, D. A.; Rich, S. S.; Rotter, J. I.; Tsao, P. S.; Assimes, T. L.; Pritchard, J. K.
10.1101/2021.12.06.471235 — genetics — Posted on 2021-12-08
2974 Cerebellar contributions to a brainwide network for flexible behavior
Verpeut, J. L.; Bergeler, S.; Kislin, M.; Townes, F. W.; Klibaite, U.; Dhanerawala, Z. M.; Hoag, A.; Jung, C.; Lee, J.; Pisano, T. J.; Seagraves, K. M.; Shaevitz, J. W.; Wang, S. S.- H.
10.1101/2021.12.07.471685 — neuroscience — Posted on 2021-12-08
2975 A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
Ramdas, S.; Judd, J.; Graham, S. E.; Kanoni, S.; Wang, Y.; Surakka, I.; Wenz, B.; Clarke, S. L.; Chesi, A.; Wells, A.; Bhatti, K. F.; Vedantam, S.; Winkler, T. W.; Locke, A. E.; Marouli, E.; Zajac, G. J.; Wu, K.-H. H.; Ntalla, I.; Hui, Q.; Klarin, D.; Hilliard, A. T.; Wang, Z.; Xue, C.; Thorleifsson, G.; Helgadottir, A.; Gudbjartsson, D. F.; Holm, H.; Olafsson, I.; Hwang, M. Y.; Han, S.; Akiyama, M.; Sakaue, S.; Terao, C.; Kanai, M.; Zhou, W.; Brumpton, B. M.; Rasheed, H.; Havulinna, A. S.; Veturi, Y.; Pacheco, J. A.; Rosenthal, E. A.; Lingren, T.; Feng, Q.; Kullo, I. J.; Narita, A.; Takayama,
10.1101/2021.12.07.470215 — genomics — Posted on 2021-12-08
2976 RNA2Immune: A Manually Curated Database of Experimentally Supported Data Linking Noncoding RNA Regulation to the Immune System
Wang, J.; Li, S.; Wang, T.; Xu, S.; Wang, X.; Kong, X.; Lu, X.; Zhang, H.; Li, L.; Feng, M.; Ning, S.; Wang, L.
10.1101/2021.12.07.471559 — immunology — Posted on 2021-12-08
2979 A rapid prototyping approach for intensive field courses to build scientific and professional skills
Nicotra, A. B.; Geange, S. R.; Abdulbahar, N.; Carle, H.; Catling, A. A.; Garcia, A.; Harris, R. J.; Head, M.; Jin, M.; Whitehead, M. R.; Zurcher, H.; Beckmann, E. A.
10.1101/2021.12.06.471369 — scientific communication and education — Posted on 2021-12-08
2980 Complementary role of mathematical modeling in preclinical glioblastoma: differentiating poor drug delivery from drug insensitivity
Urcuyo, J. C.; Massey, S. C.; Hawkins-Daarud, A.; Marin, B.-M.; Burgenske, D. M.; Sarkaria, J. N.; Swanson, K. R.
10.1101/2021.12.07.471540 — cancer biology — Posted on 2021-12-08
2981 The single-cell transcriptional landscape of lung carcinoid tumors
Bischoff, P.; Trinks, A.; Wiederspahn, J.; Obermayer, B.; Pett, J. P.; Jurmeister, P.; Elsner, A.; Dziodzio, T.; Rückert, J.-C.; Neudecker, J.; Falk, C.; Beule, D.; Sers, C.; Morkel, M.; Horst, D.; Klauschen, F.; Blüthgen, N.
10.1101/2021.12.07.471416 — cancer biology — Posted on 2021-12-08
2982 Telomere-Dependent Interleukin-1 Receptor Activation Promotes Immune Suppression in Triple-Negative-Breast Cancer
Mukherjee, A. K.; Singh, A.; Sharma, S.; Roy, S. S.; Sengupta, A.; Dutta, S.; Vinayagamurthy, S.; Bagri, S.; Khanna, D.; Chatterjee, M.; Verma, M.; Soni, D.; Budharaja, A.; Bhisade, S. K.; Sengupta, V.; Perwez, A.; Faruq, M.; Gupta, I.; Chowdhury, S.
10.1101/2021.12.07.471419 — cancer biology — Posted on 2021-12-08
2984 Aedes koreicus, a vector on the rise: pan-European genetic patterns, mitochondrial and draft genome sequencing
Kurucz, K.; Zeghbib, S.; Arnoldi, D.; Marini, G.; Manica, M.; Michelutti, A.; Montarsi, F.; Deblauwe, I.; Van Bortel, W.; Smitz, N.; Pfitzner, W.-P.; Czajka, C.; Joest, A.; Kalan, K.; Jana Susnjar, J.; Ivovic, V.; Kuczmog, A.; Lanszki, Z.; Toth, G. E.; Somogyi, B. A.; Herczeg, R.; Urban, P.; Bueno Mari, R.; Soltesz, Z.; Kemenesi, G.
10.1101/2021.12.07.471561 — genetics — Posted on 2021-12-08
2985 Ocean-Warming During Embryogenesis Programs a Lasting Transcriptomic Signature in Fishes
Ripley, D. M.; Garner, T.; Hook, S. A.; Verissimo, A.; Grunow, B.; Moritz, T.; Clayton, P.; Shiels, H. A.; Stevens, A.
10.1101/2021.12.07.470713 — developmental biology — Posted on 2021-12-08
2986 Genetic, environmental and intrinsic determinants of the human antibody epitope repertoire
Andreu-Sanchez, S.; Bourgonje, A. R.; Vogl, T.; Kurilshikov, A.; Leviatan, S.; Ruiz Moreno, A. J.; Hu, S.; Sinha, T.; Vich Vila, A.; Klompus, S.; Kalka, I.; de Leeuw, K.; Arends, S.; Jonkers, I. H.; Withoff, S.; Lifelines cohort study, ; Brouwer, E.; Weinberger, A.; Wijmenga, C.; Segal, E.; Weersma, R. K.; Fu, J.; Zhernakova, A.
10.1101/2021.12.07.471553 — immunology — Posted on 2021-12-08
2990 A magnetic field prevents alcoholic liver disease by reducing oxidative stress
Song, C.; Chen, H.; Yu, B.; Zhang, L.; Wang, J.; Feng, C.; Yang, X.; Tian, X.; Fan, Y.; Ji, X.; Wang, H.; Xie, C.; Zhang, X.
10.1101/2021.12.07.471564 — physiology — Posted on 2021-12-08
2992 The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: the case of the spike A222V mutation
Ginex, T.; Marco-Marin, C.; Wieczor, M.; P. Mata, C.; Krieger, J.; Lopez-Redondo, M. L.; Frances-Gomez, C.; Ruiz-Rodriguez, P.; Melero, R.; Sanchez-Sorzano, C. O.; Martinez, M.; Gougeard, N.; Forcada-Nadal, A.; Zamora-Caballero, S.; Gozalbo-Rovira, R.; Sanz-Frasquet, C.; Bravo, J.; Rubio, V.; Marina, A.; The IBV-Covid19-Pipeline, ; Geller, R.; Comas, I.; Gil, C.; Coscolla, M.; Orozco, M.; Llacer, J. L.; Carazo, J.-M.
10.1101/2021.12.05.471263 — molecular biology — Posted on 2021-12-08
2997 Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway
Garcia, I.; Munoz, S.; Ramos-Alonso, L.; Andersen, A. N.; Zimmermann, C.; Eriksson, J.; Boe, S. O.; Kaferle, P.; Papamichos-Chronakis, M.; Chymkowitch, P.; Enserink, J.
10.1101/2021.05.19.443414 — cell biology — Posted on 2021-12-08
2998 Plasmodium DDI1 is a potential dual-therapeutic target and essential chromatin-associated protein
Tanneru, N.; Nivya, M. A.; Adhikari, N.; Saxena, K.; Rizvi, Z.; Sudhakar, R.; Nagwani, A. K.; Atul, ; Al-Nihmi, F. M. A.; Arun Kumar, K.; Sijwali, P. S.
10.1101/2021.10.29.466443 — cell biology — Posted on 2021-12-08
2999 Population-level asymmetry of the cerebral cortex: reproducibility, lifespan changes, heritability, and individual differences
Roe, J. M.; Vidal-Pineiro, D.; Amlien, I. K.; Pan, M.; Sneve, M. H.; Thiebaut de Schotten, M.; Friedrich, P.; Sha, Z.; Francks, C.; Wang, Y.; Walhovd, K. B.; Fjell, A. M.; Westerhausen, R.
10.1101/2021.11.25.469988 — neuroscience — Posted on 2021-12-08
3002 In vitro analysis of the effects of acetaminophen, ibuprofen and aspirin on motility of female adult Onchocerca volvulus worms
Otabil, K. B.; Antwi, R. K.; Nyarko, P.; Babae, T. N.; Ankrah, B.; Bart-Plange, E. J.; Kyei, R.; Ameyaw, J.; Bamfo, J. G.; Gyasi, S. F.; Schallig, H. D.
10.1101/2021.10.20.465198 — microbiology — Posted on 2021-12-08
3004 A platform of patient-derived microtumors identifies individual treatment responses and therapeutic vulnerabilities in ovarian cancer.
Anderle, N.; Koch, A.; Gierke, B.; Keller, A.-L.; Staebler, A.; Hartkopf, A.; Brucker, S.; Pawlak, M.; Schenke-Layland, K.; Schmees, C.
10.1101/2021.11.10.468007 — cancer biology — Posted on 2021-12-08
3006 CADHERIN mediated AMIS localisation
Liang, X.; Weberling, A.; Hii, C. Y.; Zernicka-Goetz, M.; Buckley, C. E.
10.1101/2021.11.30.470571 — developmental biology — Posted on 2021-12-08
3007 OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Cho, N. H.; Cheveralls, K. C.; Brunner, A.-D.; Kim, K.; Michaelis, A. C.; Raghavan, P.; Kobayashi, H.; Savy, L.; Li, J. Y.; Canaj, H.; Kim, J. Y. S.; Setwart, E. M.; Gnann, C.; McCarthy, F.; Cabrera, J. P.; Brunetti, R. M.; Chhun, B. B.; Dingle, G.; Hein, M. Y.; Huang, B.; Mehta, S. B.; Weissman, J. S.; Gomez-Sjoberg, R.; Itzhak, D. N.; Royer, L. A.; Mann, M.; Leonetti, M. D.
10.1101/2021.03.29.437450 — cell biology — Posted on 2021-12-08
3008 Methylation pattern of nc886 in non-human mammals
Kostiniuk, D.; Tamminen, H.; Mishra, P.; Marttila, S.; Raitoharju, E.
10.1101/2021.12.03.471165 — molecular biology — Posted on 2021-12-08
3009 Distinct within-host bacterial populations ensure function, colonization and transmission in leaf symbiosis
Acar, T.; Moreau, S.; Coen, O.; De Meyer, F.; Leroux, O.; Beaumel, M.; Wilkin, P.; Carlier, A.
10.1101/2021.12.06.471530 — microbiology — Posted on 2021-12-08
3011 Tissue remodeling and cell signaling underpin changes in tumor microenvironment heterogeneity in glioma oncogenesis
Dinevska, M.; Widodo, S. S.; Furst, L.; Cuzcano, L.; Fang, Y.; Mangiola, S.; Neeson, P. J.; Darcy, P. K.; Ramsay, R. G.; MacKay, F.; Stylli, S. S.; Mantamadiotis, T.
10.1101/2021.12.05.471299 — cancer biology — Posted on 2021-12-07
3014 A chromosome-level reference genome of Ensete glaucum gives insight into diversity, chromosomal and repetitive sequence evolution in the Musaceae
Wang, Z.; Rouard, M.; Biswas, M. K.; Droc, G.; Cui, D.; Roux, N.; Baurens, F.-C.; Ge, X.-J.; Schwarzacher, T.; Heslop-Harrison, J.; Liu, Q.
10.1101/2021.11.23.469474 — plant biology — Posted on 2021-12-07
3018 Effects of Ancestry and Hypopigmentation Alleles on Skin Color in a Caribbean Native American Population
Ang, K. C.; Canfield, V. A.; Foster, T. C.; Reid, K. P.; Leong, S. L.; Kawasawa, Y. I.; Liu, D.; Hawley, J.; Cheng, K. C.
10.1101/2021.11.24.469305 — genetics — Posted on 2021-12-07
3019 Adventive larval parasitoids reconstruct their close association with spotted-wing drosophila in the invaded North American range
Abram, P. K.; Franklin, M. T.; Hueppelsheuser, T.; Carrillo, J.; Grove, E.; Eraso, P.; Acheampong, S.; Keery, L.; Girod, P.; Tsuruda, M.; Clausen, M.; Buffington, M.; Moffat, C. E.
10.1101/2021.12.06.471517 — ecology — Posted on 2021-12-07
3020 A tail of plumage colouration: disentangling geographic, seasonal, and dietary effects on plumage colour in a migratory songbird
Mahoney, S. M.; Reudink, M. W.; Contina, A.; Roberts, K. A.; Schabert, V. T.; Gunther, E. G.; Covino, K. M.
10.1101/2021.07.09.451669 — ecology — Posted on 2021-12-07
3022 CADHERIN mediated AMIS localisation
Liang, X.; Weberling, A.; Hii, C. Y.; Zernicka-Goetz, M.; Buckley, C. E.
10.1101/2021.11.30.470571 — developmental biology — Posted on 2021-12-07
3023 Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells
Vilaplana-Lopera, N.; Almaghrabi, R.; Papatzikas, G.; Cuminetti, V.; Gonzalez, E.; Jeeves, M.; Cunningham, A.; Erdem, A.; Schnuetgen, F.; Raghavan, M.; Potluri, S.; Cazier, J.-B.; Schuringa, J. J.; Reed, M. A.; Arranz, L.; Gunther, U. L.; Garcia, P.
10.1101/2021.01.21.427406 — cell biology — Posted on 2021-12-07
3024 IHF regulates host colonization factors in the bee gut symbiont Frischella perrara
Schmidt, K.; Leopold-Messer, S.; El Chazli, Y.; Emery, O.; Steiner, T.; Piel, J.; Engel, P.
10.1101/2021.12.06.471457 — microbiology — Posted on 2021-12-07
3026 BDNF-dependent modulation of axonal transport is selectively impaired in ALS
Tosolini, A. P.; Sleigh, J. N.; Surana, S.; Rhymes, E. R.; Cahalan, S. D.; Schiavo, G.
10.1101/2021.12.06.471484 — neuroscience — Posted on 2021-12-07
3028 Co-allocation to overlapping dendritic branches in the retrosplenial cortex integrates contextual memories across time
Sehgal, M.; Almeida-Filho, D.; Kastellakis, G.; Kim, S.; Lee, J.; Martin, S.; Mejia, I. D.; Pekcan, A.; Huang, S.; Lavi, A.; Heo, W. D.; Poirazi, P.; Trachtenberg, J. T.; Silva, A. J.
10.1101/2021.10.28.466343 — neuroscience — Posted on 2021-12-07
3030 Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies
Koss, D. J.; Erskine, D.; Porter, A.; Palmowski, P.; Leite, M.; Attems, J.; Outeiro, T. F.
10.1101/2021.10.20.465125 — pathology — Posted on 2021-12-07
3031 A platform of patient-derived microtumors identifies individual treatment responses and therapeutic vulnerabilities in ovarian cancer.
Anderle, N.; Koch, A.; Gierke, B.; Keller, A.-L.; Staebler, A.; Hartkopf, A.; Brucker, S.; Pawlak, M.; Schenke-Layland, K.; Schmees, C.
10.1101/2021.11.10.468007 — cancer biology — Posted on 2021-12-07
3032 A cell-based screen identifies HDAC inhibitors as activators of RIG-I signaling
Fraile-Bethencourt, E.; Foss, M. H.; Nelson, D.; Malhotra, S. V.; Anand, S.
10.1101/2021.09.28.462211 — cancer biology — Posted on 2021-12-07
3036 Taxonomy Analysis in Bacterial Kingdom based onProtein Domain: A Comparison Study
Wang, B.; Zhou, J.; Jin, Y.; Hu, M.; Zhao, Y.; Wang, X.; Yang, H.; Gong, X.; Zhang, F.; Zhang, Z.; Kang, F.; Liang, L.; Yue, J.; Ren, H.
10.1101/2021.09.17.460715 — bioinformatics — Posted on 2021-12-07
3037 A flexible workflow for building spectral libraries from narrow window data independent acquisition mass spectrometry data
Heil, L. R.; Fondrie, W. E.; McGann, C. D.; Federation, A. J.; Noble, W. S.; MacCoss, M. J.; Keich, U.
10.1101/2021.11.22.469568 — bioinformatics — Posted on 2021-12-07
3038 A new twist in ABC transporter mediated multidrug resistance - Pdr5 is a drug/proton co-transporter
Wagner, M.; Blum, D.; Raschka, S.; Nentwig, L.-M.; Gertzen, C.; Chen, M.; Gatsogiannis, C.; Harris, A.; Smits, S.; Wagner, R.; Schmitt, L.
10.1101/2021.05.26.445758 — biochemistry — Posted on 2021-12-07
3040 Ecological Network assembly: how the regional meta web influence local food webs
Saravia, L. A.; Marina, T. I.; Kristensen, N. P.; De Troch, M.; Momo, F. R.
10.1101/340430 — ecology — Posted on 2021-12-07
3042 Chemical, molecular, and single cell analysis reveal chondroitin sulfate proteoglycan aberrancy in fibrolamellar carcinoma
Francisco, A.; Li, J.; Farghli, A.; Kanke, M.; Shui, B.; Soloway, P.; Wang, Z.; Reid, L.; Liu, J.; Sethupathy, P.
10.1101/2021.12.07.471610 — cancer biology — Posted on 2021-12-07
3044 MacroH2A impedes metastatic growth by enforcing a discrete dormancy program in disseminated cancer cells
Sun, D.; Filipescu, D.; Hasson, D.; Singh, D. K.; Carcamo, S.; Khalil, B.; Miles, B.; Westra, W.; Sproll, K. C.; Bernstein, E.; Aguirre-Ghiso, J. A.
10.1101/2021.12.07.471619 — cancer biology — Posted on 2021-12-07
3045 Pre-meiotic pairing of homologous chromosomes during Drosophila male meiosis
Rubin, T.; Macaisne, N.; Valles, A. M.; Guilleman, C.; Gaugue, I.; HUYNH, J.-R.
10.1101/2021.12.07.471586 — developmental biology — Posted on 2021-12-07
3046 A phenotypic rescue approach identifies lineage regionalization defects in a mouse model of DiGeorge syndrome.
Lania, G.; Franzese, M.; Noritaka, A.; Bilio, M.; Russo, A.; D'Agostino, E.; Angelini, C.; Kelly, R. G.; Baldini, A.
10.1101/2021.12.07.471208 — developmental biology — Posted on 2021-12-07
3048 Integrin-driven Axon Regeneration in the Spinal Cord Activates a Distinctive CNS Regeneration Program
Cheah, M.; Cheng, Y.; Petrova, V.; Cimpean, A.; Jendelova, P.; Swarup, V.; Woolf, C. J.; Geschwind, D.; Fawcett, J.
10.1101/2021.12.07.471602 — neuroscience — Posted on 2021-12-07
3049 The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells
Niu, F.; Han, P.; Zhang, J.; She, Y.; Yang, L.; Yu, J.; Zhuang, M.; Tang, K.; Shi, Y.; Yang, B.; Liu, C.; Peng, B.; Ji, S.-J.
10.1101/2021.12.07.471547 — neuroscience — Posted on 2021-12-07
3051 CaMK1D signaling in AgRP neurons promotes ghrelin-mediated food intake
Vivot, K.; Meszaros, G.; Zhang, Z.; Erbs, E.; Yeghiazaryan, G.; Quinones, M.; Grandgirard, E.; Schneider, A.; Clauss--Creusot, E.; Charlet, A.; Faour, M.; Martin, C.; Luquet, S.; Kloppenburg, P.; Nogueiras, R.; Ricci, R.
10.1101/2021.12.07.471546 — physiology — Posted on 2021-12-07
3052 Zebrafish xenografts to isolate unique human breast cancer metastatic cell populations
Xiao, J.; McGill, J. R.; Nasir, A.; Lekan, A.; Johnson, B.; Wilkins, D. J.; Pearson, G. W.; Tanner, K.; Goodarzi, H.; Glasgow, E.; Schlegel, R.; Agarwal, S.
10.1101/2021.12.07.471608 — cancer biology — Posted on 2021-12-07
3053 Microneedle-mediated intratumoral delivery of anti-CTLA-4 promotes cDC1-dependent eradication of oral squamous cell carcinoma with limited irAEs
Gilardi, M.; Saddawi-Konefka, R.; Wu, V. H.; Lopez-Ramirez, M. A.; Wang, Z.; Soto, F.; Steffen, D. J.; Proietto, M.; Mikulski, Z.; Miki, H.; Sharabi, A.; Kupor, D.; Rueda, R.; Hollern, D. P.; Wang, J.; Gutkind, J. S.
10.1101/2021.12.07.471658 — cancer biology — Posted on 2021-12-07
3054 Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform
Naranjo, S.; Cabana, C. M.; LaFave, L. M.; Westcott, P. M.; Romero, R.; Ghosh, A.; Liao, L. Z.; Schenkel, J. M.; Del Priore, I.; Bhutkar, A.; Yang, D.; Jacks, T.
10.1101/2021.12.07.471632 — cancer biology — Posted on 2021-12-07
3058 A predictive microfluidic model of human glioblastoma to assess trafficking of blood-brain barrier penetrant nanoparticles
Straehla, J. P.; Hajal, C.; Safford, H. C.; Offeddu, G.; Boehnke, N.; Dacoba, T.; Wyckoff, J.; Kamm, R. D.; Hammond, P. T.
10.1101/2021.12.07.471663 — bioengineering — Posted on 2021-12-07
3059 Characterization of mutations causing steroid 21-hydroxylase 1 deficiency in Brazilian and Portuguese populations.
Prado, M. J.; Singh, S.; Ligabue-Braun, R.; Meneghetti, B. V.; Rispoli, T.; Kopacek, C.; Monteiro, K.; Zaha, A.; Rossetti, M. L. R.; Pandey, A. V.
10.1101/2021.12.07.471616 — biochemistry — Posted on 2021-12-07
3060 Direct Imaging and Identification of Proteoforms up to 70 kDa from Human Tissue
Su, P.; McGee, J. P.; Durbin, K. R.; Hollas, M. A. R.; Yang, M.; Neumann, E. K.; Allen, J. L.; Drown, B. S.; Butun, F. A.; Greer, J. B.; Early, B. P.; Fellers, R. T.; Spraggins, J. M.; Laskin, J.; Camarillo, J. M.; Kafader, J. O.; Kelleher, N. L.
10.1101/2021.12.07.471638 — biochemistry — Posted on 2021-12-07
3062 From STRs to SNPs via ddRAD-seq: geographic assignment of confiscated tortoises at reduced costs
Biello, R.; Zampiglia, M.; Fuselli, S.; Fabbri, G.; Bisconti, R.; Chiocchio, A.; Trucchi, E.; Canestrelli, D.; Bertorelle, G.
10.1101/2021.12.07.471568 — genomics — Posted on 2021-12-07
3064 Chemical induction of gut β-like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetes
Kitamoto, T.; Lee, Y.-K.; McKimpson, W. M.; Watanabe, H.; Sultana, N.; Du, W.; Fan, J.; Diaz, B.; Lin, H. V.; Leibel, R. L.; Belvedere, S.; Accili, D.
10.1101/2021.12.07.471572 — developmental biology — Posted on 2021-12-07
3070 Inhibiting Host Protein Deposition on Urinary Catheters Reduces Urinary Tract Infections
Andersen, M. J.; Fong, C.; LaBella, A. A.; Molesan, A. J.; Champion, M. M.; Howell, C.; Flores-Mireles, A. L.
10.1101/2021.12.07.471578 — microbiology — Posted on 2021-12-07
3071 Atypical B cells upregulate co-stimulatory molecules during malaria and secrete antibodies with T follicular helper cell support
Hopp, C. S.; Skinner, J.; Anzick, S. L.; Tipton, C. M.; Peterson, M. E.; Li, S.; Doumbo, S.; Kayentao, K.; Ongoiba, A.; Martens, C.; Traore, B.; Crompton, P. D.
10.1101/2021.12.07.471601 — immunology — Posted on 2021-12-07
3074 Decoding the absolute stoichiometric composition and structural plasticity of α-carboxysomes
Sun, Y.; Harman, V.; Johnson, J.; Chen, T.; Dykes, G.; Lin, Y.; Beynon, R. J.; Liu, L.
10.1101/2021.12.06.471529 — biochemistry — Posted on 2021-12-07
3077 Adventive larval parasitoids reconstruct their close association with spotted-wing drosophila in the invaded North American range
Abram, P. K.; Franklin, M. T.; Hueppelsheuser, T.; Carrillo, J.; Grove, E.; Eraso, P.; Acheampong, S.; Keery, L.; Girod, P.; Tsuruda, M.; Clausen, M.; Buffington, M.; Moffat, C. E.
10.1101/2021.12.06.471517 — ecology — Posted on 2021-12-07
3080 Distinct within-host bacterial populations ensure function, colonization and transmission in leaf symbiosis
Acar, T.; Moreau, S.; Coen, O.; De Meyer, F.; Leroux, O.; Beaumel, M.; Wilkin, P.; Carlier, A.
10.1101/2021.12.06.471530 — microbiology — Posted on 2021-12-07
3081 Impaired LAIR-1-mediated immune control due to collagen degradation in fibrosis
Carvalheiro, T.; Marut, W.; Pascoal Ramos, M. I.; Garcia, S.; Fleury, D.; Affandi, A. J.; Meijers, A. S.; Giovannone, B.; Tieland, R. G.; Elshof, E.; Ottria, A.; Cossu, M.; Meizlish, M. L.; Veenendaal, T.; Ramanujam, M.; Moreno-Garcia, M. E.; Klumperman, J.; Liv, N.; Radstake, T. R. D. J.; Meyaard, L.
10.1101/2021.12.07.471103 — immunology — Posted on 2021-12-07
3087 Neuron-like function of the nephron central command
Gyarmati, G.; Shroff, U. N.; Riquier-Brison, A.; Stocker, S. D.; Izuhara, A.; Deepak, S.; Chen, Y.; Biemesderfer, D.; James, A.; Minichiello, L.; Zlokovic, B. V.; Peti-Peterdi, J.
10.1101/2021.12.06.471478 — physiology — Posted on 2021-12-07
3090 Revised International Staging System (R-ISS) stage-dependent analysis uncovers oncogenes and potential immunotherapeutic targets in multiple myeloma
Gong, B.; Yuan, X.; Zhang, Q.; Jiang, T.; Li, H.; Xiao, J.; Li, C.; Luo, L.; Shuai, P.; Wang, L.; Liu, Y.; Yu, M.; Shi, Y.; Zhang, W.; Zhang, Y.; Zhong, L.
10.1101/2021.12.06.471423 — cancer biology — Posted on 2021-12-07
3096 Cohesin modulates DNA replication to preserve genome integrity
Wu, J.; Liu, Y.; Zhangding, Z.; Liu, X.; Ai, C.; Gan, T.; Liu, Y.; Yin, J.; Zhang, W.; Hu, J.
10.1101/2021.12.06.471507 — genetics — Posted on 2021-12-07
3098 Active communities and growth of soil microorganisms are framed by mean annual precipitation in three California annual grasslands
Foley, M. M.; Blazewicz, S. J.; McFarlane, K. J.; Greenlon, A.; Hayer, M.; Kimbrel, J. A.; Koch, B. J.; Morrison, K.; Morrissey, E. M.; Hungate, B. A.; Pett-Ridge, J.
10.1101/2021.12.06.471491 — ecology — Posted on 2021-12-07
3102 Phosphorylation dynamics in a flg22-induced, G-protein dependent network in Arabidopsis thaliana
Watkins, J. M.; Clark, N. M.; Song, G.; Oliveira, C. C.; Mishra, B.; Brachova, L.; Siefert, C. M.; Mitchell, M. S.; dos Reis, P. B.; Urano, D.; Mukhtar, S.; Walley, J. W.; Jones, A. M.
10.1101/2021.12.07.471565 — cell biology — Posted on 2021-12-07
3106 Receptor binding and escape from Beta antibody responses drive Omicron-B.1.1.529 evolution
Zahradnik, J.; Tuekprakhon, A.; Ginn, H. M.; Duyvesteyn, H. M. E.; Bahar, M.; Khan, S.; Avinoam, O.; Zhou, D.; Nutalai, R.; Supasa, P.; Wang, B.; Dejnirattisai, W.; Liu, C.; Dijokaite, A.; Temperton, N.; Mongkolsapaya, J.; Fry, E. E.; Ren, J.; Screaton, G. R.; Schreiber, G.; Stuart, D. I.
10.1101/2021.12.03.471045 — microbiology — Posted on 2021-12-07
3108 A zebrafish model of COVID-19-associated cytokine storm syndrome reveals differential proinflammatory activities of Spike proteins of SARS-CoV-2 variants of concern.
Tyrkalska, S. D.; Martinez-Lopez, A.; Arroyo, A. B.; Martinez-Morcillo, F. J.; Candel, S.; Mesa-del-Castillo, P.; Garcia-Moreno, D.; Cayuela, M. L.; Mulero, V.
10.1101/2021.12.05.471277 — immunology — Posted on 2021-12-07
3110 Imaging-Guided Bioreactor for De-Epithelialization and Long-Term Cultivation of Ex Vivo Rat Trachea
Mir, S. M.; Chen, J.; Pinezich, M.; O'Neill, J.; Huang, S.; Vunjak-Novakovic, G.; Kim, J.
10.1101/2021.12.06.470803 — bioengineering — Posted on 2021-12-07
3113 The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: the case of the spike A222V mutation
Ginex, T.; Marco-Marin, C.; Wieczor, M.; P. Mata, C.; Krieger, J. M.; Lopez-Redondo, M. L.; Frances-Gomez, C.; Ruiz-Rodriguez, P.; Melero, R.; Sanchez-Sorzano, C. O.; Martinez, M.; Gougeard, N.; Forcada-Nadal, A.; Zamora-Caballero, S.; Gozalbo-Rovira, R.; Sanz-Frasquet, C.; Bravo, J.; Rubio, V.; Marina, A.; The IBV-Covid19-Pipeline, ; Geller, R.; Comas, I.; Gil, C.; Coscolla, M.; Orozco, M.; Carazo, J.-M.
10.1101/2021.12.05.471263 — molecular biology — Posted on 2021-12-07
3114 SARS-CoV-2 infection of olfactory epithelial cells and neurons drives acute lung injury and lethal COVID-19 in mice
Tang, A.; Buccholz, D. W.; Szigety, K.; Imbhiaka, B.; Gao, S.; Frankfurter, M.; Wang, M.; Yang, J.; Hewins, P.; Mericko-Ishizuka, P.; Leu, N.; Sterling, S.; Monreal, I.; Sahler, J.; August, A.; Zhu, X.; Jurado, K.; Xu, M.; Morrisey, E.; Millar, S.; Aguilar-Carreno, H.; Kahn, M.
10.1101/2021.12.04.471245 — microbiology — Posted on 2021-12-07
3115 The dual function monoclonal antibodies VIR-7831 and VIR-7832 demonstrate potent in vitro and in vivo activity against SARS-CoV-2
Cathcart, A. L.; Havenar-Daughton, C.; Lempp, F. A.; Ma, D.; Schmid, M.; Agostini, M. L.; Guarino, B.; Di iulio, J.; Rosen, L.; Tucker, H.; Dillen, J.; Subramanian, S.; Sloan, B.; Bianchi, S.; Wojcechowskyj, J.; Zhou, J.; Kaiser, H.; Chase, A.; Lauron, E.; Montiel-Ruiz, M.; Spreafico, R.; Noack, J.; Czudnochowski, N.; Sahakyan, A.; Pinto, D.; Saliba, C.; Culap, K.; Delotta, E.; Park, A.; Cameroni, E.; Ledoux, S.; Werts, A.; Colas, C.; Soriaga, L.; Telenti, A.; Purcell, L. A.; Hwang, S.; Snell, G.; Virgin, H. W.; Corti, D.; Hebner, C. M.
10.1101/2021.03.09.434607 — immunology — Posted on 2021-12-07
3116 BDNF-dependent modulation of axonal transport is selectively impaired in ALS
Tosolini, A. P.; Sleigh, J. N.; Surana, S.; Rhymes, E. R.; Cahalan, S. D.; Schiavo, G.
10.1101/2021.12.06.471484 — neuroscience — Posted on 2021-12-07
3117 A remote lecture series roadmap to equity, diversity, and inclusion in STEM
Boyle, E. A.; Goldberg, G.; Schmok, J. C.; Burgado, J.; Izidro Layng, F.; Grunwald, H. A.; Balotin, K. M.; Cuoco, M. S.; Chang, K.-C.; Ecklu-Mensah, G.; Arakaki, A. K. S.; Ahmed, N.; Garcia Arceo, X.; Jagannatha, P.; Pekar, J.; Iyer, M.; DASL Alliance, ; Yeo, G. W.
10.1101/2021.12.05.471284 — scientific communication and education — Posted on 2021-12-07
3118 Processing body dynamics drive non-genetic MEK inhibitors tolerance by fine-tuning KRAS and NRAS translation
Vidal-Cruchez, O.; Nicolini, V. J.; Rete, T.; Rezzonico, R.; Lacoux, C.; Fassy, J.; Jacquet, K.; Domdom, M. A.; Ventujol, C.; Juhel, T.; Romeo, B.; Roux, J.; Hubstenberger, A.; Mari, B.; Mograbi, B.; Hofman, P.; Brest, P.
10.1101/2021.12.06.471470 — cancer biology — Posted on 2021-12-07
3119 Structure-based design of a chemical probe set for the 5-HT5A serotonin receptor
Kaplan, A. L.; Strachan, R. T.; Braz, J. M.; Craik, V.; Slocum, S.; Mangano, T.; Amabo, V.; O'Donnell, H. R.; Lak, P.; Basbaum, A.; Roth, B. L.; Shoichet, B. K.
10.1101/2021.12.06.471449 — biophysics — Posted on 2021-12-07
3122 Fast off-rate CD229 chimeric antigen receptor T cells efficiently target multiple myeloma, spare T cells, and exhibit reduced trogocytosis
Vander Mause, E. R.; Baker, J. M.; Radhakrishnan, S. V.; Davis, P.; Panse, J.; Marvin, J. E.; Olson, M. L.; Steinbach, M.; Ng, D. P.; Lim, C. S.; Atanackovic, D.; Luetkens, T.
10.1101/2021.12.06.471279 — bioengineering — Posted on 2021-12-07
3123 A convolutional neural network highlights mutations relevant to antimicrobial resistance in Mycobacterium tuberculosis
Green, A. G.; Yoon, C. H.; Chen, M. L.; Freschi, L.; Gröschel, M. I.; Kohane, I. S.; Beam, A.; Farhat, M. R.
10.1101/2021.12.06.471431 — genomics — Posted on 2021-12-07
3127 Slit-Robo Signalling Establishes a Sphingosine-1-Phosphate Gradient to Polarise Fin Mesenchyme and Establish Fin Morphology
Mahabaleshwar, H.; P.V., A.; Loo, T. Y. J.; Koh, S. Y.; Pitman, M. R.; Kwok, S.; Ma, J.; Hu, B.; Lin, F.; Lok, X. L.; Pitson, S. M.; Saunders, T. E.; Carney, T. J.
10.1101/2021.12.07.471519 — cell biology — Posted on 2021-12-07
3129 Transactive response DNA-binding Protein (TDP-43) regulates early HIV-1 entry and infection.
Cabrera-Rodriguez, R.; Perez-Yanes, S.; Gonzalez-Montelongo, R.; Lorenzo-Salazar, J. M.; Estevez-Herrera, J.; Garcia-Luis, J.; Inigo-Campos, A.; Rubio-Rodriguez, L. A.; Munoz-Barrera, A.; Trujillo-Gonzalez, R.; Dorta-Guerra, R.; Casado, C.; Pernas, M.; Blanco, J.; Flores, C.; Valenzuela-Fernandez, A.
10.1101/2021.12.06.471424 — immunology — Posted on 2021-12-07
3130 Visual imagery vividness declines across the lifespan
Gulyas, E.; Sutori, S.; Lovas, A.; Ziman, G.; Gombos, F.; Kovacs, I.
10.1101/2021.12.06.471435 — neuroscience — Posted on 2021-12-07
3132 Phosphorylation dynamics in a flg22 induced, heterotrimeric G protein dependent signaling network in Arabidopsis thaliana reveals a candidate PP2A phosphatase involved in AtRGS1 trafficking
Watkins, J. M.; Jones, A. M.; Walley, J.; Clark, N. M.; Urano, D.; Mishra, B.; Mukhtar, M. S.; Oliveira, C.; Song, G.; Brachova, L.; Seifert, C.; Mitchell, M.; Reis, P.
10.1101/2021.12.06.471472 — systems biology — Posted on 2021-12-07
3136 Through-plane super-resolution with autoencoders in diffusion magnetic resonance imaging of the developing human brain
Kebiri, H.; Canales-Rodriguez, E. J.; Lajous, H.; de Dumast, P.; Girard, G.; Aleman-Gomez, Y.; Koob, M.; Jakab, A.; Cuadra, M. B.
10.1101/2021.12.06.471406 — bioinformatics — Posted on 2021-12-07
3138 Summary statistics knockoff inference empowers identification of putative causal variants in genome-wide association studies
He, Z.; Liu, L.; Belloy, M. E.; Le Guen, Y.; Sossin, A.; Liu, X.; Qi, X.; Ma, S.; Wyss-Coray, T.; Tang, H.; Sabatti, C.; Candes, E.; Greicius, M. D.; Ionita-Laza, I.
10.1101/2021.12.06.471440 — genetics — Posted on 2021-12-07
3139 Stepwise evolution of a butterfly supergene via duplication and inversion
Kim, K.-W.; De-Kayne, R.; Gordon, I. J.; Omufwoko, K. S.; Martins, D. J.; ffrench-Constant, R.; Martin, S. H.
10.1101/2021.12.06.471392 — evolutionary biology — Posted on 2021-12-07
3144 Sociodemographic effects on immune cell composition in a free-ranging non-human primate.
Rosado, M. R. S.; Marzan-Rivera, N.; Watowich, M. M.; Pantoja, P.; Pavez-Fox, M. A.; Siracusa, E. R.; Negron-Del Valle, J. E.; Phillips, D.; Ruiz-Lambides, A.; Cayo Biobank Research Unit, ; Martinez, M. I.; Montague, M. J.; Platt, M. L.; Higham, J. P.; Brent, L. J. N.; Sariol, C. A.; Snyder-Mackler, N.
10.1101/2021.12.06.471383 — immunology — Posted on 2021-12-07
3146 Graded variation in cortical T1w/T2w myelination during adolescence
Baum, G. L.; Flournoy, J. C.; Glasser, M. F.; Harms, M. P.; Mair, P.; Sanders, A.; Barch, D.; Buckner, R. L.; Bookheimer, S.; Dapretto, M.; Smith, S. M.; Thomas, K. M.; Yacoub, E.; Van Essen, D. C.; Somerville, L. H.
10.1101/2021.12.06.471432 — neuroscience — Posted on 2021-12-07
3149 EpyNN: Educational python for Neural Networks
Malard, F.; Danner, L.; Rouzies, E.; Meyer, J. G.; Lescop, E.; Olivier-Van Stichelen, S.
10.1101/2021.12.06.470764 — scientific communication and education — Posted on 2021-12-07
3153 PEDOT:PSS-Modified Cotton Conductive Thread for Mass Manufacturing of Textile-Based Electrical Wearable Sensors by Computerized Embroidery
Alshabouna, F.; Lee, H. S.; Barandun, G.; Tan, E.; Cotur, Y.; Asfour, T.; Gonzalez-Macia, L.; Coatsworth, P.; Nunez-Bajo, E.; Kim, J. S.; Guder, F.
10.1101/2021.12.06.471240 — bioengineering — Posted on 2021-12-07
3159 Response plasticity of Drosophila olfactory sensory neurons
Halty-deLeon, L.; Pal Mahadevan, V.; Hansson, B. S.; Wicher, D.
10.1101/2021.12.06.471362 — neuroscience — Posted on 2021-12-07
3162 Disentangling hand and tool processing: distal effects of neuromodulation
Amaral, L.; Donato, R.; Valerio, D.; Caparelli-Daquer, E.; Almeida, J.; Bergstrom, F.
10.1101/2021.12.06.471144 — neuroscience — Posted on 2021-12-07
3169 Cathelicidin-3 associated with serum extracellular vesicles enables early diagnosis of a transmissible cancer
Espejo, C.; Wilson, R.; Pye, R. J.; Ratcliffe, J. C.; Ruiz-Aravena, M.; Willms, E.; Wolfe, B. W.; Hamede, R.; Hill, A. F.; Jones, M. E.; Woods, G. M.; Lyons, A. B.
10.1101/2021.12.06.471373 — cancer biology — Posted on 2021-12-07
3170 Tissue remodeling and cell signaling underpin changes in tumor microenvironment heterogeneity in glioma oncogenesis
Dinevska, M.; Widodo, S. S.; Furst, L.; Cuzcano, L.; Fang, Y.; Mangiola, S.; Neeson, P. J.; Darcy, P. K.; Ramsay, R. G.; MacKay, F.; Stylli, S. S.; Mantamadiotis, T.
10.1101/2021.12.05.471299 — cancer biology — Posted on 2021-12-07
3171 Oscillatory movement of a dynein-microtubule complex crosslinked with DNA origami
Hirose, K.; Higuchi, H.; Abdellatef, S. A.; Tadakuma, H.; Yan, K.; Fujiwara, T.; Fukumoto, K.; Kondo, Y.; Takazaki, H.; Boudria, R.; Yasunaga, T.
10.1101/2021.12.06.471346 — biophysics — Posted on 2021-12-07
3173 Mitochondrial mutational spectrum is associated with mammalian longevity: a novel signature of oxidative damage.
Mikhailova, A. G.; Mikhailova, A. A.; Ushakova, K.; Tretiakov, E.; Shamanskiy, V. A.; Iurchenko, A.; Zazhytska, M.; Kozenkova, E.; Zdobnov, E. M.; Makeev, V.; Yurov, V.; Tanaka, M.; Gostimskaya, I.; Fleischmann, Z. M.; Annis, S.; Franco, M.; Wasko, K.; Kunz, W.; Knorre, D.; Mazunin, I.; Nikolaev, S.; Fellay, J.; Reymond, A.; Khrapko, K.; Gunbin, K.; Popadin, K.
10.1101/2021.12.03.460832 — bioinformatics — Posted on 2021-12-07
3175 Low-affinity CAR T cells exhibit reduced trogocytosis, preventing fratricide and antigen-negative tumor escape while preserving anti-tumor activity
Olson, M. L.; Vander Mause, E. R.; Radhakrishnan, S. V.; Brody, J. D.; Rapoport, A. P.; Welm, A. L.; Atanackovic, D.; Luetkens, T.
10.1101/2021.12.05.471117 — bioengineering — Posted on 2021-12-07
3177 Growth rate as a modulator of tooth patterning during adaptive radiations
Sadier, A.; Anthwal, N.; Krause, A.; Dessalles, R.; Lake, M.; Bentolila, L.; Haase, R.; Nieves, N.; Santana, S.; Sears, K. E.
10.1101/2021.12.05.471324 — evolutionary biology — Posted on 2021-12-07
3179 Variants with the N501Y mutation extend SARS-CoV-2 host range to mice, with contact transmission
Montagutelli, X.; Prot, M.; Levillayer, L.; Baquero Salazar, E.; Jouvion, G.; Conquet, L.; Beretta, M.; Donati, F.; Albert, M.; Gambaro, F.; Behillil, S.; Enouf, V.; Rousset, D.; Jaubert, J.; van der Werf, S.; Mouquet, H.; Rey, F.; Simon-Loriere, E.
10.1101/2021.03.18.436013 — microbiology — Posted on 2021-12-07
3180 A human monoclonal antibody potently pan-neutralizes SARS-CoV-2 VOCs by targeting RBD invariant sites
Wang, X.; Hu, A.; Chen, X.; Zhang, Y.; Yu, F.; Yue, S.; Li, A.; Zhang, J.; Pan, Z.; Yang, Y.; Lin, Y.; Gao, L.; Zhou, J.; Zhao, J.; Li, F.; Shi, Y.; Huang, F.; Yang, X.; Peng, Y.; Tu, L.; Zhang, H.; Zheng, H.; He, J.; Zhang, H.; Xu, L.; Huang, Q.; Zhu, Y.; Deng, K.; Ye, L.
10.1101/2021.11.29.470356 — immunology — Posted on 2021-12-07
3181 Sleep Dependent Changes of Lactate Concentration in Human Brain
Yildiz, S.; Lim, M. M.; Sammi, M. K.; Powers, K.; Murchison, C. F.; Iliff, J. J.; Rooney, W. D.
10.1101/2021.12.05.471196 — neuroscience — Posted on 2021-12-07
3188 Met/HGFR triggers detrimental reactive microglia in TBI
Rehman, R.; Miller, M.; Krishnamurthy, S.; Kjell, J.; Elsayed, L.; olde Heuvel, F.; Conquest, A.; Chandrasekar, A.; Ludolph, A. C.; Boeckers, T.; Mulaw, M.; Goetz, M.; Morganti-Kossmann, M. C.; Takeoka, A.; Roselli, F.
10.1101/2021.12.05.471232 — neuroscience — Posted on 2021-12-07
3189 Sequence-dependent model of genes with dual σ factor preference
Calado Baptista, I. S.; Kandavalli, V.; Chauhan, V.; Mohamed Bahrudeen, M. N.; Almeida, B. L. d. B.; Palma, C. S. D.; Dash, S.; Ribeiro, A.
10.1101/2021.11.17.468920 — systems biology — Posted on 2021-12-07
3192 NAD metabolism modulates mitochondrial function and inflammation and prevents progression of diabetic kidney disease
Myakala, K.; Wang, X.; Jones, B. A.; Hirschey, M. D.; Yang, X.; Rosenberg, A. Z.; Ginley, B.; Sarder, P.; Brodsky, L.; Jang, Y.; Na, C. H.; Chi, Y.; Zhang, X.; Guha, U.; Lewien, P.; Wu, C.; Bansal, S.; Ma, J.; Cheema, A.; Panov, J.; Levi, M.
10.1101/2021.12.05.471273 — pathology — Posted on 2021-12-07
3194 Characterization of epigenetic alterations in esophageal cancer by whole-genome bisulfite sequencing
Pan, F.; Yu, S.-X.; Wang, X.; Huang, H.-C.; Cai, Z.-Y.; Wang, J.-M.; Lin, S.-Y.; Gao, Y.-L.; Li, E.-M.; Xu, L.-Y.
10.1101/2021.12.05.471340 — cancer biology — Posted on 2021-12-07
3195 SARS-CoV-2 variants impact RBD conformational dynamics and ACE2 accessibility
Valerio, M. F.; Borges-Araujo, L.; Melo, M. N.; Lousa, D.; Soares, C. M.
10.1101/2021.11.30.470470 — biophysics — Posted on 2021-12-07
3201 Improving replicability using interaction with laboratories: a multi-lab experimental assessment
Jaljuli, I.; Kafkafi, N.; Giladi, E.; Golani, I.; Gozes, I.; Chesler, E.; Bogue, M. A.; Bemjamini, Y.
10.1101/2021.12.05.471264 — animal behavior and cognition — Posted on 2021-12-07
3203 Modulation of behavioral and hippocampal transcriptomic responses in rat prolonged chronic unpredictable stress model by fluoxetine, eicosapentaenoic acid and lipopolysaccharide
Demin, K. A.; Kolesnikova, T. O.; Galstyan, D. S.; Krotova, N. A.; Ilyin, N. P.; Derzhavina, K. A.; Seredinskaya, M.; Kositsyn, Y. M.; Sorokin, D. V.; Nerush, M. O.; Khaybaev, A.-A. S.; Pushkareva, S. A.; Strekalova, T.; Masharsky, A.; Kalueff, A. V.
10.1101/2021.12.05.471274 — neuroscience — Posted on 2021-12-07
3204 Vestibular Agnosia is linked to abnormal functional brain networks
Hadi, Z.; Pondeca, Y. J.; Calzolari, E.; Chepisheva, M. K.; Smith, R. M.; Mahmud, M. S.; Rust, H.; Sharp, D. J.; Seemungal, B. M.
10.1101/2021.12.03.471139 — neuroscience — Posted on 2021-12-07
3205 The Effect of Spatial Frequency on the Visual Category Representation in the Macaque Inferior Temporal Cortex
Farhang, E.; Toosi, R.; Karami, B.; Koushki, R.; Rezayat, E.; Shakerian, F.; Noroozi, J.; Dehaqani, M.-R. A.
10.1101/2021.12.05.470960 — neuroscience — Posted on 2021-12-07
3208 Efemp1 modulates elastic fiber formation and mechanics of the extrahepatic bile duct
Llewellyn, J.; Roberts, E.; Liu, C.; Naji, A.; Assoian, R. K.; Wells, R. G.
10.1101/2021.12.05.471313 — physiology — Posted on 2021-12-07
3209 Decrowding Expansion Pathology: Unmasking Previously Invisible Nanostructures and Cells in Intact Human Brain Pathology Specimens
Valdes, P. A.; Yu, C.-C.; Aronson, J. L.; Zhao, Y.; Bernstock, J. D.; Bhere, D.; An, B.; Viapiano, M. S.; Shah, K.; Chiocca, E. A.; Boyden, E. S.
10.1101/2021.12.05.471271 — bioengineering — Posted on 2021-12-07
3210 Dairy vs. beef production - expert views on welfare
Mandel, R.; Bracke, M. B. M.; Nicol, C. J.; Webster, J.; Gygax, L.
10.1101/2021.12.06.471462 — animal behavior and cognition — Posted on 2021-12-07
3211 Denoising-based Image Compression for Connectomics
Minnen, D.; Januszewski, M.; Blakely, T.; Shapson-Coe, A.; Schalek, R. L.; Balle, J.; Lichtman, J. W.; Jain, V.
10.1101/2021.05.29.445828 — neuroscience — Posted on 2021-12-07
3214 Identifying cell-to-cell variability in internalisation using flow cytometry
Browning, A. P.; Ansari, N.; Drovandi, C.; Johnston, A. P.; Simpson, M. J.; Jenner, A. L.
10.1101/2021.11.24.469957 — cell biology — Posted on 2021-12-07
3217 Distributed Feedforward and Feedback Processing across Perisylvian Cortex Supports Human Speech
Wang, R.; Chen, X.; Khalilian-Gourtani, A.; Yu, L.; Dugan, P.; Friedman, D.; Doyle, W.; Devinsky, O.; Wang, Y.; Flinker, A.
10.1101/2021.12.06.471521 — neuroscience — Posted on 2021-12-07
3222 Prdm16 and Notch functionally and physically interact during artery development
Beerens, M.; Van Wauwe, J.; Craps, S.; KC, A.; Finck, C.; Daems, M.; Leigh, N.; MacRae, C. A.; Luttun, A.
10.1101/2021.12.05.471275 — developmental biology — Posted on 2021-12-07
3225 Exophers are components of mammalian cell neurobiology in health and disease
Siddique, I.; Di, J.; Williams, C. K.; Markovic, D.; Vinters, H. V.; Bitan, G.
10.1101/2021.12.06.471479 — cell biology — Posted on 2021-12-07
3226 Nucleotide imbalance decouples cell growth from cell proliferation
Diehl, F. F.; Miettinen, T. P.; Elbashir, R.; Nabel, C. S.; Manalis, S. R.; Lewis, C. A.; Vander Heiden, M. G.
10.1101/2021.12.06.471399 — cell biology — Posted on 2021-12-07
3227 Age-dependent aggregation of ribosomal RNA-binding proteins links deterioration in chromatin stability with loss of proteostasis
Paxman, J.; Zhou, Z.; O'Laughlin, R.; Li, Y.; Tian, W.; Su, H.; Jiang, Y.; Holness, S. E.; Stasiowski, E.; Tsimring, L.; Pillus, L.; Hasty, J.; Hao, N.
10.1101/2021.12.06.471495 — cell biology — Posted on 2021-12-07
3230 Heterozygous transcriptional and nonsense decay signatures in blood outgrowth endothelial cells from patients with hereditary haemorrhagic telangiectasia
Bernabeu-Herrero, M. E.; Patel, D.; Bielowka, A.; Srikaran, S.; Chaves Guerrero, P.; Govani, F. S.; Mollet, I. G.; Noseda, M.; Aldred, M. A.; Shovlin, C. L.
10.1101/2021.12.05.471269 — cell biology — Posted on 2021-12-06
3231 Systematic identification of yeast mutants with increased rates of cell death reveals rapid stochastic necrosis associated with cell division
Alexandrov, A. I.; Grosfeld, E. V.; Mitkevich, O. V.; Bidiuk, V. A.; Nostaeva, A. V.; Kukhtevich, I. V.; Schneider, R.; Shilov, E. S.; Kushnirov, V. V.; Dmitriev, S. E.; Gladyshev, V. N.
10.1101/2021.10.20.465133 — cell biology — Posted on 2021-12-07
3234 Determinants of Murine Skin Microbiota Composition in Homeostasis and Wound Healing
Galbraith, J.; Legrand, J.; Muller, N.; Baz, B.; Togher, K.; Matigian, N.; Kang, S.; Young, S.; Mortlock, S.; Roy, E.; Morahan, G.; Walker, G.; Morrison, M.; Khosrotehrani, K.
10.1101/2021.06.20.449197 — systems biology — Posted on 2021-12-06
3238 The S-palmitoylome and DHHC-PAT interactome of Drosophila melanogaster S2R+ cells indicate a high degree of conservation to mammalian palmitoylomes
Porcellato, E.; Gonzalez, J. C.; Ahlmann-Eltze, C.; Elsakka, M. A.; Shapira, I.; Fritsch, J.; Navarro, J. A.; Anders, S.; Russell, R. B.; Wielnad, F. T.; Metzendorf, C.
10.1101/2021.12.06.471463 — biochemistry — Posted on 2021-12-06
3239 Dairy vs. beef production - expert views on welfare
Mandel, R.; Bracke, M. B. M.; Nicol, C. J.; Webster, J.; Gygax, L.
10.1101/2021.12.06.471462 — animal behavior and cognition — Posted on 2021-12-06
3243 Pandemic-scale phylogenetics
Ye, C.; Thornlow, B.; Kramer, A. M.; McBroome, J.; Hinrichs, A. S.; Corbett-Detig, R.; Turakhia, Y.
10.1101/2021.12.03.470766 — bioinformatics — Posted on 2021-12-06
3244 Modeling the trajectory of SARS-CoV-2 spike protein evolution in continuous latent space using a neural network and Gaussian process
King, S.; Chen, X. E.; Ng, S. W. S.; Rostin, K.; Roberts, T.; Hahn, S. V.; Schwab, J. C.; Sekhon, P.; Kagieva, M.; Reilly, T.; Qi, R. C.; Salman, P.; Hong, R. J.; Ma, E. J.; Hallam, S. J.
10.1101/2021.12.04.471198 — bioinformatics — Posted on 2021-12-06
3245 SAVED by a toxin: Structure and function of the CRISPR Lon protease.
Rouillon, C.; Schneberger, N.; Chi, H.; Peter, M. F.; Geyer, M.; Boenigk, W.; Seifert, R.; White, M. F.; Hagelueken, G.
10.1101/2021.12.06.471393 — biochemistry — Posted on 2021-12-06
3247 Functional Anatomy of the TDP-43 Redox Sensor
zhou, x.; Sumrow, L.; Sutherland, L.; Liu, D.; Qin, T.; McKnight, S. L.; Liszczak, G.
10.1101/2021.12.05.471332 — biochemistry — Posted on 2021-12-06
3248 Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation
Soskic, B.; Cano-Gamez, E.; Smyth, D.; Ambridge, K.; Ke, Z.; Bossini-Castillo, L.; Kaplanis, J.; Ramirez Navarro, L.; Nakic, N.; Esparza-Gordillo, J.; Rowan, W.; Wille, D.; Tough, D.; Bronson, P.; Trynka, G.
10.1101/2021.12.06.470953 — genomics — Posted on 2021-12-06
3249 Genetic conversion of a split-drive into a full-drive element
Terradas, G.; Bennett, J. B.; Li, Z.; Marshall, J. M.; Bier, E.
10.1101/2021.12.05.471291 — genetics — Posted on 2021-12-06
3253 Correspondence between gene expression and neurotransmitter receptor and transporter density in the human brain
Hansen, J. Y.; Markello, R. D.; Tuominen, L.; Norgaard, M.; Kuzmin, E.; Palomero-Gallagher, N.; Dagher, A.; Misic, B.
10.1101/2021.11.30.469876 — neuroscience — Posted on 2021-12-06
3257 A new protocol for speed vernalisation of winter cereals
Cha, J.-K.; O'Connor, K.; Alahmad, S.; Lee, J.-H.; Dinglasan, E.; Park, H.; Lee, S.-M.; Hirsz, D.; Kwon, S.-W.; Kwon, Y.; Kim, K.-M.; Ko, J.-M.; Hickey, L.; Shin, D.; Dixon, L.
10.1101/2021.12.01.470717 — plant biology — Posted on 2021-12-06
3258 Electrical Stimulated GLUT4 Signaling Attenuates Critical Illness-Associated Muscle Wasting
Addinsall, A. B.; Cacciani, N.; Backeus, A.; Hedstrom, Y.; Shevchenko, G.; Bergquist, J.; Larsson, L.
10.1101/2021.11.11.468054 — physiology — Posted on 2021-12-06
3261 Quality control of large genome datasets using genome fingerprints
Robinson, M.; Joshi, A.; Vidyarthi, A.; Maccoun, M.; Rangavajjhala, S.; Glusman, G.
10.1101/600254 — genomics — Posted on 2021-12-06
3262 THO and TRAMP complexes prevent transcription-replication conflicts, DNA breaks, and CAG repeat contractions
Brown, R. E.; Su, X. A.; Fair, S.; Wu, K.; Verra, L.; Jong, R.; Andrykovich, K.; Freudenreich, C. H.
10.1101/2021.12.06.471001 — genetics — Posted on 2021-12-06
3263 TRAP1 and cyclophilin D compete at OSCP subunit to regulate enzymatic activity and permeability transition pore opening by F-ATP synthase
Cannino, G.; Urbani, A.; Gaspari, M.; Varano, M.; Negro, A.; Filippi, A.; Ciscato, F.; Masgras, I.; Gerle, C.; Tibaldi, E.; Brunati, A. M.; Lippe, G.; Bernardi, P.; Rasola, A.
10.1101/2021.12.06.471412 — cell biology — Posted on 2021-12-06
3264 Cistrome and transcriptome analysis identifies unique androgen receptor (AR) and AR- V7 splice variant chromatin binding and transcriptional activities
Paul, B.; Robertson, M. J.; Bingman, W. E.; Dash, A. K.; Krause, W. C.; Shafi, A. A.; Piyarathna, B.; Coarfa, C.; Weigel, N. L.
10.1101/2021.12.06.471341 — molecular biology — Posted on 2021-12-06
3265 A two-step metagenomics approach for prey identification from the blood meals of common vampire bats (Desmodus rotundus)
Chua, P. Y. S.; Caroe, C.; Crampton-Platt, A.; Reyes-Avila, C. S.; Jones, G.; Streicker, D. G.; Bohmann, K.
10.1101/2021.12.06.470776 — molecular biology — Posted on 2021-12-06
3267 N-acetyl-cysteinylated streptophenazines fromStreptomyces
Vind, K.; Maffioli, S. I.; Fernandez Ciruelos, B.; Waschulin, V.; Brunati, C.; Simone, M.; Sosio, M.; Donadio, S.
10.1101/2021.12.06.470720 — microbiology — Posted on 2021-12-06
3269 Salmonella enterica serovar Typhimurium chitinases modulate the intestinal glycome and promote small intestinal invasion.
Devlin, J. R.; Santus, W.; Mendez, J.; Peng, W.; Yu, A.; Wang, J.; Alejandro-Navarreto, X.; Kiernan, K.; Singh, M.; Jiang, P.; Mechref, Y.; Behnsen, J.
10.1101/2021.12.06.471358 — microbiology — Posted on 2021-12-06
3272 IHF regulates host colonization factors in the bee gut symbiont Frischella perrara
Schmidt, K.; Leopold-Messer, S.; El Chazli, Y.; Emery, O.; Steiner, T.; Piel, J.; Engel, P.
10.1101/2021.12.06.471457 — microbiology — Posted on 2021-12-06
3273 Endowing Universal CAR T-cell with Immune-Evasive Properties using TALEN-Gene Editing.
Jo, S.; Das, S.; Williams, A.; Chretien, A.-s.; Pagliardini, T.; Leroy, A.; postigo-fernandez, j.; leclerre, D.; jahangiri, B.; chion-sotinel, i.; Gouble, A.; Dusseaux, M.; Galetto, r.; Duclert, a.; Marcenaro, E.; Devillier, R.; Olive, D.; Duchateau, p.; Poirot, L.; Valton, J.
10.1101/2021.12.06.471451 — immunology — Posted on 2021-12-06
3275 An exploratory study of EEG connectivity during the first year of life in preterm and full-term infants
Gonzalez-Moreira, E.; Paz-Linares, D.; Cubero-Rego, L.; Areces-Gonzalez, A.; Hinojosa-Rodriguez, M.; Valdes-Sosa, P. A.; Harmony, T.
10.1101/2021.11.24.469864 — neuroscience — Posted on 2021-12-06
3277 The Neuroanatomy of Speech Processing: A Large-Scale Lesion Study
Rogalsky, C.; Basilakos, A.; Rorden, C.; Pillay, S.; LaCroix, A. N.; Keator, L.; Mickelsen, S.; Anderson, S. W.; Love, T.; Fridriksson, J.; Binder, J.; Hickok, G.
10.1101/2020.04.02.022822 — neuroscience — Posted on 2021-12-06
3279 Unevolved proteins from modern and prebiotic amino acids manifest distinct structural profiles
Tretyachenko, V.; Vymetal, J.; Neuwirthova, T.; Vondrasek, J.; Fujishima, K.; Hlouchova, K.
10.1101/2021.08.29.458031 — synthetic biology — Posted on 2021-12-06
3280 A nuclear import pathway exploited by pathogenic noncoding RNAs
Ma, J.; Mudiyanselage, S. D. D.; Park, W. J.; Wang, M.; Takeda, R.; Liu, B.; Wang, Y.
10.1101/2021.12.02.470923 — plant biology — Posted on 2021-12-06
3281 Cancer tolerance to chromosomal instability is driven by Stat1 inactivation in vivo
Schubert, M.; Hong, C.; Jilderda, L. J.; Requesens-Rueda, M.; Tijhuis, A. E.; Simon, J. E.; Bakker, P. L.; Cooper, J.; Damaskou, A.; Wardenaar, R.; Bakker, B.; Gupta, S.; van den Brink, A.; Andrade-Ruiz, L.; Koster, M. H.; Youssef, S. A.; Luinenburg, D.; Strong, A.; Engleiter, T.; Ponstingl, H.; de Haan, G.; de Bruin, A.; Rad, R.; Nijman, H. W.; Medema, R. H.; van Vugt, M. A.; de Bruyn, M.; Spierings, D. C. J.; Colome-Tatche, M.; Vassiliou, G.; Foijer, F.
10.1101/2021.12.03.471107 — cancer biology — Posted on 2021-12-06
3283 TRAWLING: a Transcriptome Reference AWare of spLIciNG events.
Di Nanni, N.; Reyes Quiroz, A.; Ho, D.; Ihry, R.; Kauffmann, A.; Durand, E. Y.; de Weck, A.
10.1101/2021.12.03.471115 — bioinformatics — Posted on 2021-12-06
3284 Interactions of SARS-CoV-2 protein E with cell junctions and polarity PDZ-containing proteins
Zhu, Y.; Alvarez, F.; Wolff, N.; Mechaly, A.; Brule, S.; Neitthoffer, B.; Etienne-Manneville, s.; Haouz, A.; Boeda, B.; Caillet-Saguy, C.
10.1101/2021.12.04.471219 — biochemistry — Posted on 2021-12-06
3288 UPF3A and UPF3B are redundant and modular activators of nonsense-mediated mRNA decay in human cells
Wallmeroth, D.; Boehm, V.; Lackmann, J.-W.; Altmueller, J.; Dieterich, C.; Gehring, N. H.
10.1101/2021.07.07.451444 — molecular biology — Posted on 2021-12-06
3291 LINE-1 retrotransposons facilitate horizontal gene transfer into poxviruses
Rahman, M. J.; Haller, S. L.; Stoian, A. M. M.; Li, J.; Brennan, G.; Rothenburg, S.
10.1101/2020.10.26.355610 — microbiology — Posted on 2021-12-06
3294 Relationships between pond water and tilapia skin microbiomes in aquaculture ponds in Malawi
McMurtrie, J.; Alathari, S.; Chaput, D. L.; Bass, D.; Ghambi, C.; Nagoli, J.; Delamare-Deboutteville, J.; Mohan, C. V.; Cable, J.; Temperton, B.; Tyler, C. R.
10.1101/2021.12.06.470702 — microbiology — Posted on 2021-12-06
3295 Carbon Dot-based Fluorescent Antibody Nanoprobes as Brain Tumour Glioblastoma Diagnostics.
Ghirardello, M.; Shyam, R.; Liu, X.; Garcia Millan, T.; Sittel, I.; Ramos Soriano, J.; Galan, M. C.; Kurian, K.
10.1101/2021.11.29.470408 — immunology — Posted on 2021-12-06
3297 Tonic engagement of nicotinic receptors bidirectionally controls striatal spiny projection neuron spike timing
Matityahu, L.; Malgady, J.; Schirelman, M.; Johansson, Y.; Wilking, J.; Silberberg, G.; Goldberg, J. A.; Plotkin, J. L.
10.1101/2021.11.02.466870 — neuroscience — Posted on 2021-12-06
3300 Evolutionary dynamics of sex-biased gene expression in a young XY system: Insightsfrom the brown alga genus Fucus
Hatchett, W. J.; Jueterbock, A. O.; Kopp, M.; Coyer, J. A.; Coelho, S. M.; Hoarau, G. G.; Lipinska, A. P.
10.1101/2021.08.12.455804 — evolutionary biology — Posted on 2021-12-06
3301 Cryptic local adaptation is pervasive across environmental and evolutionary gradients
Sparks, M. M.; Kraft, J. C.; Blackstone, K. M.; McNickle, G. G.; Christie, M. R.
10.1101/2021.12.05.471216 — ecology — Posted on 2021-12-06
3304 LungMAP Portal Ecosystem: Systems-Level Exploration of the Lung
Gaddis, N.; Fortriede, J.; Guo, M.; Bardes, E. E.; Kouril, M.; Tabar, S.; Burns, K.; Ardini-Poleske, M. E.; Loos, S.; Schnell, D.; Jin, K.; Iyer, B.; Du, Y.; Korte, J.; Munshi, R.; Smith, V.; Herbst, A.; Kitzmiller, J. A.; Clair, G. C.; Carson, J.; Adkins, J.; Morrisey, E. E.; Pryhuber, G. S.; Misra, R.; Whitsett, J. A.; Sun, X.; Heathorn, T.; Paten, B.; Prasath, V. B. S.; Xu, Y.; Tickle, T.; Aronow, B. J.; Salomonis, N.
10.1101/2021.12.05.471312 — systems biology — Posted on 2021-12-06
3307 Modeling implanted metals in electrical stimulation applications
Mercadal, B.; Salvador, R.; Biagi, M. C.; Bartolomei, F.; Wendling, F.; Ruffini, G.
10.1101/2021.12.04.471211 — bioengineering — Posted on 2021-12-06
3310 Does the brain care about averages? A simple test.
Tlaie, A.; Shapcott, K. A.; Tiesinga, P.; Schölvinck, M.; Havenith, M. N.
10.1101/2021.11.28.469673 — neuroscience — Posted on 2021-12-06
3311 Mapping the signatures of inflammatory pain and its relief
Bohic, M.; Pattison, L. A.; Jhumka, Z. A.; Rossi, H.; Thackray, J. K.; Ricci, M.; Foster, W.; Arnold, J.; Mossazghi, N.; Tischfield, M. A.; Yttri, E. A.; Smith, E. S. J.; Abdus-Saboor, I.; Abraira, V. E.
10.1101/2021.06.16.448689 — neuroscience — Posted on 2021-12-06
3313 WESTPA 2.0: High-performance upgrades for weighted ensemble simulations and analysis of longer-timescale applications
Russo, J.; Zhang, S.; Leung, J.; Bogetti, A.; Thompson, J.; DeGrave, A.; Torrillo, P.; Pratt, A. J.; Wong, K.; Xia, J.; Copperman, J. T.; Adelman, J.; Zwier, M.; LeBard, D.; Zuckerman, D. M.; Chong, L.
10.1101/2021.12.05.471280 — biophysics — Posted on 2021-12-06
3316 Assessment of AI-based Protein Structure Prediction for the NLRP3 Target
Yin, J.; Yu, J.; Cui, W.; Lei, J.; Chen, W.; Satz, A. L.; Zhou, Y.; Feng, H.; Deng, J.; Su, W.; Kuai, L.
10.1101/2021.11.05.467381 — biochemistry — Posted on 2021-12-06
3319 Evaluating the role of coevolution in a horizontally transmitted mutualism
Stoy, K. S.; Chavez, J.; De Las Casas, V.; Talla, V.; Berasategui, A.; Morran, L. T.; Gerardo, N. M.
10.1101/2021.12.04.471243 — evolutionary biology — Posted on 2021-12-06
3320 Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment
Papadas, A.; Deb, G.; Officer, A.; Cicala, A.; Hope, C.; Emmerich, P.; Wiesner, J.; Pagenkopf, A.; Arauz, G.; Bansal, V.; Matkowskyj, K.; Deming, D. A.; Politi, K.; Abrams, S.; Harismendy, O.; Asimakopoulos, F.
10.1101/2021.11.10.467836 — immunology — Posted on 2021-12-06
3321 Why do hippocampal mossy cells matter? It depends on the frequency and context.
Kolaric, K.; Strauch, C.; Li, Y.; Woods, S.; Lopes, M. A.; Sivarajah, N.; Teixeira, C. M.; Lerch, J.; Frankland, P. W.; Henkelman, M.; Bortolotto, Z. A.; Warburton, E. C.; Bashir, Z. I.; Manahan-Vaughan, D.; Atan, D.
10.1101/2021.12.04.467951 — neuroscience — Posted on 2021-12-06
3324 TRAWLING: a Transcriptome Reference Aware of spLIciNG events.
di nanni, n.; reyes quiroz, a.; ho, d.; ihry, r.; kauffmann, a.; durand, e.; de weck, a.
10.1101/2021.12.03.471115 — bioinformatics — Posted on 2021-12-06
3327 Redox regulation of PTPN22 affects the severity of T cell dependent autoimmune inflammation
James, J.; Chen, Y.; Hernandez, C.; Forster, F.; Dagnell, M.; Cheng, Q.; Saei, A. A.; Gharibi, H.; Lahore, G. F.; Astrand, A.; Malhotra, R.; Malissen, B.; Zubarev, R. A.; Arner, E.; Holmdahl, R.
10.1101/2021.12.02.470976 — immunology — Posted on 2021-12-06
3328 Modulating effects of FGF12 variants on NaV1.2 and NaV1.6 associated with Developmental and Epileptic Encephalopathy and Autism Spectrum Disorder
Seiffert, S.; Pendziwiat, M.; Bierhals, T.; Goel, H.; Schwarz, N.; van der Ven, A.; Bosselmann, C. M.; Willemsen, M. H.; Hedrich, U. B. S.; Helbig, I.; Weber, Y. G.
10.1101/2021.12.03.471090 — neuroscience — Posted on 2021-12-06
3329 Brain-wide neural co-activations in resting human
Ding, L.; Shou, G.; Cha, Y.-H.; Sweeney, J.; Yuan, H.
10.1101/2021.12.03.471116 — neuroscience — Posted on 2021-12-06
3330 Harmonizing Functional Connectivity Reduces Scanner Effects in Community Detection
Chen, A. A.; Srinivasan, D.; Pomponio, R.; Fan, Y.; Nasrallah, I.; Resnick, S.; Beason-Held, L.; Davatzikos, C.; Satterthwaite, T.; Bassett, D. S.; Shinohara, R. T.; Shou, H.
10.1101/2021.12.03.469269 — neuroscience — Posted on 2021-12-06
3334 From fruit growth to ripening in plantain: a careful balance between carbohydrate synthesis and breakdown
Campos, N.; Colombie, S.; Moing, A.; Cassan, C.; Amah, D.; Swennen, R.; Gibon, Y.; Carpentier, S.
10.1101/2021.12.03.471126 — plant biology — Posted on 2021-12-06
3335 COP1 promotes seed germination by destabilizing RGA-LIKE2 (RGL2) in Arabidopsis
Lee, B.-D.; Yim, Y.; Canibano, E.; Kim, S.-H.; Garcia-Leon, M.; Rubio, V.; Fonseca, S.; Paek, N.-C.
10.1101/2021.12.01.470837 — plant biology — Posted on 2021-12-06
3336 SlTDP1 Is Required To Specify Tapetum Identity And For The Regulation Of Redox Homeostasis In Tomato Anthers
Salazar-Sarasua, B.; Lopez-Martin, M. J.; Roque, E.; Hamza, R.; Canas, L. A.; Beltran, J. P.; Gomez-Mena, C.
10.1101/2021.12.03.471129 — plant biology — Posted on 2021-12-06
3339 Structure of the RZZ complex and molecular basis of Spindly-driven corona assembly at human kinetochores
Raisch, T.; Ciossani, G.; d'Amico, E.; Cmentowski, V.; Carmignani, S.; Maffini, S.; Merino, F.; Wohlgemuth, S.; Vetter, I. R.; Raunser, S.; Musacchio, A.
10.1101/2021.12.03.471119 — biochemistry — Posted on 2021-12-06
3341 Obesity affects mitochondrial metabolism and proliferative potential of endometrial progenitor cells
Smieszek, A.; Marcinkowska, K.; Pielok, A.; Sikora, M.; Valihrach, L.; Carnevale, E.; Marycz, K.
10.1101/2021.12.02.470884 — cell biology — Posted on 2021-12-06
3343 A new twist in ABC transporter mediated multidrug resistance - Pdr5 is a drug/proton co-transporter
Wagner, M.; Blum, D.; Raschka, S.; Nentwig, L.-M.; Gertzen, C.; Chen, M.; Gatsogiannis, C.; Szewczak-Harris, A. M.; Smits, S.; Wagner, R.; Schmitt, L.
10.1101/2021.05.26.445758 — biochemistry — Posted on 2021-12-06
3345 Enhanced transcriptional heterogeneity mediated by NF-κB super-enhancers
Wibisana, J. N.; Inaba, T.; Shinohara, H.; Yumoto, N.; Hayashi, T.; Umeda, M.; Ebisawa, M.; Nikaido, I.; Sako, Y.; Okada, M.
10.1101/2021.07.13.452147 — molecular biology — Posted on 2021-12-06
3346 What happened when? Brain and behavioral responses to modified structure and content in episodic cueing
Siestrup, S.; Jainta, B.; El-Sourani, N.; Trempler, I.; Wolf, O. T.; Cheng, S.; Schubotz, R. I.
10.1101/2021.11.10.467871 — neuroscience — Posted on 2021-12-06
3347 Epigenetic repression of Wnt receptors in AD: a role for Sirtuin2-induced H4K16ac deacetylation of Frizzled1 and Frizzled7 promoters
Palomer, E.; Martin-Flores, N.; Jolly, S.; Pascual-Vargas, P.; Benvegnu, S.; Podpolny, M.; Teo, S.; Vaher, K.; Saito, T.; Sado, T. C.; Whiting, P.; Salinas, P. C.
10.1101/2021.05.19.444683 — neuroscience — Posted on 2021-12-06
3349 Speed fluctuations of bacterial replisomes
Bhat, D.; Hauf, S.; Plessy, C.; Yokobayashi, Y.; Pigolotti, S.
10.1101/2021.10.15.464478 — biophysics — Posted on 2021-12-06
3352 Environmentally-induced DNA methylation is inherited across generations in an aquatic keystone species (Daphnia magna)
Feiner, N.; Radersma, R.; Vasquez, L.; Ringner, M.; Nystedt, B.; Raine, A.; Tobi, E. W.; Heijmans, B. T.; Uller, T.
10.1101/2021.12.05.471257 — evolutionary biology — Posted on 2021-12-05
3354 Aberrant DJ-1 expression underlies L-type calcium channel hypoactivity in tuberous sclerosis complex and Alzheimer's disease
Niere, F.; Uneri, A.; McArdle, C. J.; Cacheaux, L. P.; Egido-Betancourt, H. X.; Reynoldson, C.; Penaranda, J.; Wang, X.; Taylor, W. C.; Craft, S.; Keene, C. D.; Ma, T.; Raab-Graham, K. F.
10.1101/2020.08.26.267260 — neuroscience — Posted on 2021-12-05
3358 Massively Parallel Selection of NanoCluster Beacons
Kuo, Y.-A.; Jung, C.; Chen, Y.-A.; Kuo, H.-C.; Zhao, O. S.; Nguyen, T. D.; Rybarski, J. R.; Hong, S.; Chen, Y.-I.; Wylie, D. C.; Hawkins, J. A.; Walker, J. N.; Shields, S. W.; Brodbelt, J. S.; Petty, J. T.; Finkelstein, I. J.; Yeh, H.-C.
10.1101/2021.12.04.471212 — bioengineering — Posted on 2021-12-05
3360 TbasCO: Trait-based Comparative 'Omics Identifies Ecosystem-Level and Niche-Differentiating Adaptations of an Engineered Microbiome
McDaniel, E. A.; van Steenbrugge, J. J.; Noguera, D. R.; McMahon, K. D.; Raaijmakers, J. M.; Medema, M. H.; Oyserman, B. O.
10.1101/2021.12.04.471239 — genomics — Posted on 2021-12-05
3362 Intraspecific variation in migration timing of green sturgeon in the Sacramento River system
Colborne, S. F.; Sheppard, L. W.; O'Donnell, D. R.; Reuman, D. C.; Walter, J. A.; Singer, G. P.; Kelly, J. T.; Thomas, M. J.; Rypel, A. L.
10.1101/2021.12.03.471146 — ecology — Posted on 2021-12-05
3364 The giant staphylococcal protein Embp facilitates colonization of surfaces through Velcro-like attachment to fibrillated fibronectin
Khan, N.; Aslan, H.; Buttner, H.; Rohde, H.; Golbek, T. W.; Roeters, S. J.; Woutersen, S.; Weidner, T.; Meyer, R. L.
10.1101/2021.05.31.446437 — microbiology — Posted on 2021-12-05
3367 HippUnfold: Automated hippocampal unfolding, morphometry, and subfield segmentation
DeKraker, J.; Haast, R. A.; Yousif, M. D.; Karat, B.; Kohler, S.; Khan, A. R.
10.1101/2021.12.03.471134 — neuroscience — Posted on 2021-12-05
3368 Physiology and function of PNS axons rely on glycolic metabolism in myelinating Schwann cells
DECK, M.; Van Hameren, G.; Campbell, G.; Bernard-Marissal, N.; Devaux, J.; Berthelot, J.; Lattard, A.; Medard, J.-J.; Gautier, B.; Quintana, P.; Chao De La Barca, J. M.; Reynier, P.; Lenaers, G.; Chrast, R.; Tricaud, N.
10.1101/2020.04.23.049056 — neuroscience — Posted on 2021-12-05
3372 Lipophorin receptors regulate mushroom bodies development and participate in learning, memory, and sleep in flies
Rojo-Cortes, F.; Tapia-Valladares, V.; Fuenzalida-Uribe, N.; Hidalgo, S.; Roa, C. B.; Gonzalez-Ramirez, M.-C.; Oliva, C.; Campusano, J. M.; Marzolo, M.-P.
10.1101/2021.11.10.467940 — neuroscience — Posted on 2021-12-05
3374 Quantifying the Invasive Secondary Metabolome
Rowland-Chandler, J.; Salter, E.; Babu, S.; Yadav, G.
10.1101/2021.12.03.471125 — plant biology — Posted on 2021-12-05
3377 Biofilm Growth Under Elastic Confinement
Goldstein, R. E.; Fortune, G. T.; Oliveira, N. M.
10.1101/2021.12.05.471265 — biophysics — Posted on 2021-12-05
3378 Robust Single-cell Matching and Multi-modalAnalysis Using Shared and Distinct FeaturesReveals Orchestrated Immune Responses
Zhu, B.; Chen, S.; Bai, Y.; Chen, H.; Mukherjee, N.; Vazquez, G.; McIlwain, D. R.; Alexandar, T.; Lee, I.; Matthias, M.; Goltsev, Y.; Ma, Z.; Nolan, G. P.; Jiang, S.
10.1101/2021.12.03.471185 — bioinformatics — Posted on 2021-12-05
3381 A new substrate triggers susceptibility by uncoupling a bacterial multidrug resistance efflux pump
Spreacker, P. J.; Thomas, N. E.; Beeninga, W. F.; Brousseau, M.; Hibbs, K. M.; Henzler-Wildman, K. A.
10.1101/2021.12.04.471113 — biochemistry — Posted on 2021-12-05
3383 Cell free extrachromosomal circular DNA is common in human urine
Lv, W.; Pan, X.; Han, P.; Wang, Z.; Yuan, H.; Feng, W.; Wang, Q.; Qu, K.; Xu, Z.; Li, Y.; Zheng, T.; Lin, L.; Liu, C.; Liu, X.; Li, H.; Henriksen, R. H. A.; Bolund, L.; Lin, L.; Jin, X.; Yang, H.; Zhang, X.; Regenberg, B.; Luo, Y.
10.1101/2021.12.02.471038 — genomics — Posted on 2021-12-05
3384 What can the cold-induced transcriptomes of Arctic Brassicaceae tell us about the evolution of cold tolerance?
Birkeland, S.; Slotte, T.; Brysting, A. K.; Gustafsson, A. L. S.; Hvidsten, T. R.; Brochmann, C.; Nowak, M. D.
10.1101/2021.12.04.471218 — evolutionary biology — Posted on 2021-12-05
3385 Mosquito excreta reveals circulation of West Nile virus and its underlying ecosystem
L Ambert, G.; Gendrot, M.; Briolant, S.; Nguyen, A.; Pages, S.; Bosio, L.; Palomo, V.; Gomez, N.; Benoit, N.; Savini, H.; Pradines, B.; Durand, G. A.; Leparc-Goffart, I.; Grard, G.; Fontaine, A.
10.1101/2021.12.05.471258 — ecology — Posted on 2021-12-05
3388 Enhancing Quantitative and Data Science Education for Graduate Students in Biomedical Science
Gross, L. J.; McCord, R. P.; LoRe, S. M.; Ganusov, V. V.; Hong, T. V.; Strickland, C.; Talmy, D.; von Arnim, A. G.; Wiggins, G.
10.1101/2021.12.03.471108 — scientific communication and education — Posted on 2021-12-05
3389 Tibial nerve stimulation increases vaginal blood perfusion and bone mineral density and yield load in ovariectomized rats
Xu, J. J.; Zimmerman, L.; Soriano, V.; Mentzelopoulos, G.; Kennedy, E.; Bottorff, E.; Stephan, C.; Kozloff, K.; Devlin, M. J.; Bruns, T. M.
10.1101/2021.12.03.469332 — physiology — Posted on 2021-12-05
3390 Structure-based discovery of small molecule inhibitors of the autocatalytic proliferation of alpha-synuclein aggregates
Chia, S.; Brotzakis, Z. F.; Horne, R. I.; Possenti, A.; Mannini, B.; Cataldi, R.; Nowinska, M.; Staats, R.; Linse, S.; Knowles, T. P. J.; Habchi, J.; Vendruscolo, M.
10.1101/2021.12.05.471256 — biophysics — Posted on 2021-12-05
3395 Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells
Vilaplana-Lopera, N.; Almaghrabi, R.; Papatzikas, G.; Cuminetti, V.; Gonzalez, E.; Jeeves, M.; Cunningham, A.; Erdem, A.; Schnuetgen, F.; Raghavan, M.; Potluri, S.; Cazier, J.-B.; Schuringa, J. J.; Reed, M. A.; Arranz, L.; Gunther, U. L.; Garcia, P.
10.1101/2021.01.21.427406 — cell biology — Posted on 2021-12-05
3397 Face-Selective Responses Present in Multiple Regions of the Human Infant Brain
Kosakowski, H. L.; Cohen, M. A.; Herrera, L.; Nichoson, I.; Kanwisher, N. G.; Saxe, R.
10.1101/2021.12.04.471085 — neuroscience — Posted on 2021-12-05
3398 The veterinary anti-parasitic selamectin is a novel inhibitor of the mycobacterial DprE1 enzyme
Ezquerra-Aznarez, J. M.; Degiacomi, G.; Gasparovic, H.; Stelitano, G.; Sammartino, J. C.; Kordulakova, J.; Governa, P.; Manetti, F.; Pasca, M. R.; Chiarelli, L. R.; Ramon-Garcia, S.
10.1101/2021.12.04.471217 — microbiology — Posted on 2021-12-04
3399 Human IAPP is a driver of painful diabetic peripheral neuropathy
Asiri, M. M. H.; Versteeg, S.; Brakkee, E. M.; Coert, J. H.; Hack, C. E.; Hoppener, J. W. M.; Eijkelkamp, N.
10.1101/2021.12.03.471098 — neuroscience — Posted on 2021-12-04
3403 Extent, impact, and mitigation of batch effects in tumor biomarker studies using tissue microarrays
Stopsack, K. H.; Tyekucheva, S.; Wang, M.; Gerke, T. A.; Vaselkiv, J. B.; Penney, K. L.; Kantoff, P. W.; Finn, S. P.; Fiorentino, M.; Loda, M.; Lotan, T. L.; Parmigiani, G.; Mucci, L. A.
10.1101/2021.06.29.450369 — pathology — Posted on 2021-12-04
3404 Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors
Pan, M.; Zorbas, C.; Sugaya, M.; Ishiguro, K.; Kato, M.; Nishida, M.; Zhang, H.; Candeias, M. M.; Okamoto, A.; Ishikawa, T.; Soga, T.; Aburatani, H.; Sakai, J.; Matsumura, Y.; Suzuki, T.; Proud, C. G.; Lafontaine, D. L. G.; Osawa, T.
10.1101/2021.12.03.471189 — cancer biology — Posted on 2021-12-04
3408 Inactivation mechanism and efficacy of grape seed extract for Human Norovirus surrogate
Oh, C.; Chowdhury, R.; Samineni, L.; Shisler, J. L.; Kumar, M.; Nguyen, T. H.
10.1101/2021.12.03.471102 — biochemistry — Posted on 2021-12-04
3409 Subfamily-specific differential contribution of individual monomers and the tether sequence to mouse L1 promoter activity
Kong, L.; Saha, K.; Hu, Y.; Tschetter, J. N.; Habben, C. E.; Whitmore, L. S.; Yao, C.; Ge, X.; Ye, P.; Newkirk, S. J.; An, W.
10.1101/2021.12.03.471143 — genomics — Posted on 2021-12-04
3410 Sex bias evaluation of classic and novel Housekeeping Genes in adipose tissue through the massive analysis of transcriptomics data
Guaita-Cespedes, M.; Grillo-Risco, R.; Hidalgo, M. R.; Fernandez-Veledo, S.; Burks, D. J.; de la Iglesia-Vaya, M.; Galan, A.; Garcia-Garcia, F.
10.1101/2021.12.04.471124 — genomics — Posted on 2021-12-04
3411 Duplication of NRAMP3 gene in poplars generated two homologous transporters with distinct functions
Pottier, M.; Le Thi, V. A.; Primard-Brisset, C.; Marion, J.; Bianchi, M.; Victor, C.; Dejardin, A.; Pilate, G.; Thomine, S.
10.1101/2021.12.04.471152 — evolutionary biology — Posted on 2021-12-04
3412 Permissive aggregative group formation favors coexistence in yeast
Belpaire, T. E. R.; Pesek, J.; Lories, B.; Verstrepen, K. J.; Steenackers, H. P.; Ramon, H.; Smeets, B.
10.1101/2021.12.03.471114 — evolutionary biology — Posted on 2021-12-04
3413 Population genetics reveals cryptic lineages and ongoing hybridization in a declining migratory fish species complex
Rougemont, Q.; Perrier, C.; Besnard, A.-L.; Lebel, I.; Abdallah, Y.; Feunteun, E.; Reveillac, E.; Lasne, E.; Acou, A.; Nachon, D. J.; Cobo, F.; Evanno, G.; Bagliniere, J.-L.; Launey, S.
10.1101/2021.12.04.471201 — evolutionary biology — Posted on 2021-12-04
3417 Spatially Resolved Phosphoproteomics Reveals Fibroblast Growth Factor Receptor Recycling-driven Regulation of Autophagy and Survival
Watson, J.; Ferguson, H. R.; Brady, R. M.; Ferguson, J.; Fullwood, P.; Mo, H.; Bexley, K. H.; Knight, D.; Schwartz, J.-M.; Smith, M. P.; Francavilla, C.
10.1101/2021.12.04.471203 — cell biology — Posted on 2021-12-04
3418 RPL3L-containing ribosomes modulate mitochondrial activity in the mammalian heart
Milenkovic, I.; Santos Vieira, H. G.; Lucas, M. C.; Ruiz-Orera, J.; Patone, G.; Kesteven, S.; Wu, J.; Feneley, M.; Espadas, G.; Sabido, E.; Hubner, N.; van Heesch, S.; Voelkers, M.; Novoa, E. M.
10.1101/2021.12.04.471171 — molecular biology — Posted on 2021-12-04
3419 Deciphering the potential niche of novel black yeast fungal isolates in a biological soil crust based on genomes, phenotyping, and melanin regulation
Carr, E. C.; Barton, Q.; Grambo, S.; Renfro, C.; Sullivan, M. T.; Kuo, A.; Pangilinan, J.; Lipzen, A.; Keymanesh, K.; Savage, E.; Barry, K.; Grigoriev, I. V.; Riekhof, W. R.; Harris, S. D.
10.1101/2021.12.03.471027 — microbiology — Posted on 2021-12-04
3424 Age-dependent normalisation functions for T-lymphocytes in healthy individuals
Schroeter, J.; Borghans, J. A.; Bitter, M. W.; van Dongen, J. J.; De Boer, R. j.
10.1101/2021.12.01.470754 — immunology — Posted on 2021-12-04
3425 The Carotid Body Detects Circulating Tumor Necrosis Factor-Alpha to Activate a Sympathetic Anti-Inflammatory Reflex
Katayama, P. L.; Leirao, I. d. P.; Kanashiro, A.; Luiz, J. P. M.; Cunha, F. Q.; Navegantes, L. C. C.; Menani, J. V.; Zoccal, D. B.; Colombari, D. S. d. A.; Colombari, E.
10.1101/2021.10.20.463417 — neuroscience — Posted on 2021-12-04
3426 Long-term labeling and imaging of synaptically-connected neuronal networks in vivo using nontoxic, double-deletion-mutant rabies viruses
Jin, L.; Sullivan, H. A.; Zhu, M.; Lavin, T. K.; Matsuyama, M.; Lea, N. E.; Xu, R.; Hou, Y.; Rutigliani, L.; Pruner, M. T.; Babcock, K. R.; Ip, J. P. K.; Hu, M.; Daigle, T. L.; Zeng, H.; Sur, M.; Wickersham, I. R.
10.1101/2021.12.04.471186 — neuroscience — Posted on 2021-12-04
3431 Cancer tolerance to chromosomal instability is driven by Stat1 inactivation in vivo
Schubert, M.; Hong, C.; Jilderda, L. J.; Requesens-Rueda, M.; Tijhuis, A. E.; Simon, J. E.; Bakker, P. L.; Cooper, J.; Damaskou, A.; Wardenaar, R.; Bakker, B.; Gupta, S.; van den Brink, A.; Andrade-Ruiz, L.; Koster, M. H.; Youssef, S. A.; Luinenburg, D.; Strong, A.; Engleiter, T.; Ponstingl, H.; de Haan, G.; de Bruin, A.; Rad, R.; Nijman, H. W.; Medema, R. H.; van Vugt, M.; de Bruyn, M.; Spierings, D. C. J.; Colome-Thatche, M.; Vassiliou, G.; Foijer, F.
10.1101/2021.12.03.471107 — cancer biology — Posted on 2021-12-04
3433 Microbiome-based disease prediction with multimodal variational information bottlenecks
Grazioli, F.; Siarheyeu, R.; Alqassem, I.; Henschel, A.; Pileggi, G.; Meiser, A.
10.1101/2021.06.08.447505 — bioinformatics — Posted on 2021-12-04
3435 A genome-wide CRISPR screen identifies the glycosylation enzyme DPM1 as a modifier of DPAGT1 deficiency and ER stress
Dalton, H. M.; Viswanatha, R.; Brathwaite, R.; Zuno, J. S.; Mohr, S. E.; Perrimon, N.; Chow, C. Y.
10.1101/2021.12.03.471178 — genetics — Posted on 2021-12-04
3436 CRISPR Cas13-based tools to track and manipulate endogenous telomeric repeat-containing RNAs in living cells
Xu, M.; Chigumira, T.; Chen, Z.; Tones, J.; Zhao, R.; Dahl, K. N.; Chenoweth, D. M.; Zhang, H.
10.1101/2021.12.03.471109 — cell biology — Posted on 2021-12-04
3437 Rapid expansion of SARS-CoV-2 variants of concern is a result of adaptive epistasis
Garvin, M. R.; Prates, E. T.; Romero, J.; Cliff, A.; Gazolla, J. G. F. M.; Pickholz, M.; Pavicic, M.; Jacobson, D.
10.1101/2021.08.03.454981 — evolutionary biology — Posted on 2021-12-04
3438 Modelling of filamentous phage-induced antibiotic tolerance of P.aeruginosa
van Rossem, M. T.; Wilks, S.; Kaczmarek, M.; Secor, P. R.; DAlessandro, G.
10.1101/2021.12.03.471163 — microbiology — Posted on 2021-12-04
3439 Preclinical efficacy, safety, and immunogenicity of PHH-1V, a second-generation COVID-19 vaccine candidate based on a novel recombinant RBD fusion heterodimer of SARS-CoV-2.
Barreiro, A.; Prenafeta, A.; Bech-Sabat, G.; Roca, M.; Perozo, E.; March, R.; Gonzalez, L.; Madrenas, L.; Corominas, J.; Fernandez, A.; Molas, M.; Pentinat, T.; Panosa, C.; Moreno, A.; Puigvert, E.; Pol, E.; Palmada, J.; Garriga, C.; Prat, T.; Vergara-Alert, J.; Lorca-Oro, C.; Roca, N.; Fernandez-Bastit, L.; Rodon, J.; Perez, M.; Segales, J.; Pradenas, E.; Marfil, S.; Trinite, B.; Ortiz, R.; Clotet, B.; Blanco, J.; Diaz Pedroza, J.; Ampudia Carrasco, R.; Rosales Salgado, Y.; Loubat Casanovas, J.; Capdevila Larripa, S.; Garcia Prado, J.; Barretina Ginesta, J.; Sistere-Oro, M.; Cebollada Rica, P
10.1101/2021.11.22.469117 — immunology — Posted on 2021-12-04
3440 Regulation of ammonium acquisition and use in Oryza longistaminata ramets under nitrogen source heterogeneity
Kawai, M.; Tabata, R.; Ohashi, M.; Honda, H.; Kamiya, T.; Kojima, M.; Takebayashi, Y.; Oishi, S.; Okamoto, S.; Hachiya, T.; Sakakibara, H.
10.1101/2021.08.24.457502 — plant biology — Posted on 2021-12-04
3445 Single cell profiling of Hofbauer cells and fetal brain microglia reveals shared programs and functions
Ceasrine, A. M.; Batorsky, R.; Shook, L. L.; Kislal, S.; Bordt, E. A.; Devlin, B. A.; Perlis, R. H.; Slonim, D. K.; Bilbo, S. D.; Edlow, A. G.
10.1101/2021.12.03.471177 — developmental biology — Posted on 2021-12-04
3446 Tumor protein D54 binds intracellular nanovesicles via an amphipathic lipid packing sensor (ALPS) motif
Reynaud, A.; Magdeleine, M.; Patel, A.; Gay, A.-S.; Debayle, D.; Abelanet, S.; Antonny, B.
10.1101/2021.12.03.471088 — cell biology — Posted on 2021-12-04
3447 Regulation with cell size ensures mitochondrial DNA homeostasis during cell growth
Seel, A.; Padovani, F.; Finster, A.; Mayer, M.; Bureik, D.; Osman, C.; Klecker, T.; Schmoller, K. M.
10.1101/2021.12.03.471050 — cell biology — Posted on 2021-12-04
3449 Microglia Mediate Early Corticostriatal Synapse Loss and Cognitive Dysfunction in Huntingtons Disease Through Complement-Dependent Mechanisms
Wilton, D. K.; Mastro, K. J.; Heller, M. D.; Gergits, F. W.; Willing, C. R.; Frouin, A.; Daggett, A.; Gu, X.; Kim, A. Y.; Faull, R.; Jayadev, S.; Yednock, T.; Yang, X. W.; stevens, b.
10.1101/2021.12.03.471180 — neuroscience — Posted on 2021-12-04
3451 Striatum-projecting prefrontal cortex neurons support working memory maintenance
Chernysheva, M.; Sych, Y.; Fomins, A.; Alatorre Warren, J. L.; Lewis, C. M.; Serratosa Capdevila, L.; Boehringer, R.; Amadei, E. A.; Grewe, B. F.; O'Connor, E. C.; Hall, B.; Helmchen, F.
10.1101/2021.12.03.471159 — neuroscience — Posted on 2021-12-03
3452 Methylation pattern of nc886 in non-human mammals
Kostiniuk, D.; Tamminen, H.; Mishra, P.; Marttila, S.; Raitoharju, E.
10.1101/2021.12.03.471165 — molecular biology — Posted on 2021-12-03
3453 Modelling of filamentous phage-induced antibiotic tolerance of P.aeruginosa
van Rossem, M. T.; Wilks, S.; Kaczmarek, M.; Secor, P. R.; DAlessandro, G.
10.1101/2021.12.03.471163 — microbiology — Posted on 2021-12-03
3455 Age-related decline in function of ON and OFF visual pathways
Hathibelagal, A. R.; Prajapati, V.; Jayagopi, I.; Jalali, S.; Ganeshrao, S. B.
10.1101/2021.12.03.471168 — neuroscience — Posted on 2021-12-03
3456 Volumetric assessment and longitudinal changes of brain structures in formalinized Beagle brains
DEL SIGNORE, F.; Arribarat, G.; Della Salda, L.; Mogicato, G.; Deviers, A.; Cartiaux, B.; Vignoli, M.; Peran, P.; de Pasquale, F.
10.1101/2021.12.03.471167 — neuroscience — Posted on 2021-12-03
3457 Verification of Hypsibius exemplaris Gasiorek et al., 2018 (Eutardigrada; Hypsibiidae) application in anhydrobiosis research
Kaczmarek, Łukasz; Poprawa, I.; Bartylak, T.; Kulpla, A.; Erdmann, W.; Roszkowska, M.; Chajec, Łukasz; Karachitos, A.; Kmita, H.
10.1101/2021.12.03.471166 — zoology — Posted on 2021-12-03
3458 A Syx-RhoA-Dia1 signaling axis regulates cell cycle progression, DNA damage, and therapy resistance in glioblastoma
Lin, W.-H.; Feathers, R. W.; Cooper, L. M.; Lewis-Tuffin, L.; Sarkaria, J. N.; Anastasiadis, P. Z.
10.1101/2021.12.03.469255 — cancer biology — Posted on 2021-12-03
3460 A CRISPR toolbox for generating intersectional genetic mice for functional, molecular, and anatomical circuit mapping
Lusk, S.; McKinney, A.; Hunt, P. J.; Fahey, P. G.; Patel, J.; Chang, A.; Sun, J. J.; Martinez, V. K.; Zhu, P. J.; Egbert, J. R.; Allen, G.; Jiang, X.; Arenkiel, B. R.; Tolias, A. S.; Costa-Mattioli, M.; Ray, R. S.
10.1101/2021.06.10.447908 — genetics — Posted on 2021-12-03
3462 Single-cell transcriptome reveals insights into the development and function of the zebrafish ovary
Liu, Y.; Kossack, M. E.; Mcfaul, M. E.; Christensen, L. N.; Siebert, S.; Wyatt, S. R.; Kamei, C.; Horst, S.; Arroy, N.; Drummond, I.; Juliano, C. E.; Draper, B. W.
10.1101/2021.12.01.470669 — developmental biology — Posted on 2021-12-03
3463 Global landscape of replicative DNA polymerase usage in the human genome
Koyanagi, E.; Kakimoto, Y.; Yoshifuji, F.; Natsume, T.; Higashitani, A.; Ogi, T.; Carr, A. M.; Kanemaki, M. T.; Daigaku, Y.
10.1101/2021.11.14.468503 — molecular biology — Posted on 2021-12-03
3464 The individuality of shape asymmetries of the human cerebral cortex
Chen, Y.-C.; Arnatkeviciute, A.; McTavish, E.; Pang, J.; Chopra, S.; Suo, C.; Fornito, A.; Aquino, K. M.; The Alzheimer's Disease Neuroimaging Initiative,
10.1101/2021.09.14.460242 — neuroscience — Posted on 2021-12-03
3465 Boosting L-type Ca2+ channel activity in tuberous sclerosis mitigates excess glutamate receptors
Niere, F.; Cacheaux, L. P.; Egido-Betancourt, H. X.; Taylor, W. C.; Raab-Graham, K. F.
10.1101/2020.08.26.269209 — neuroscience — Posted on 2021-12-03
3466 Aberrant DJ-1 expression underlies L-type calcium channel hypoactivity in tuberous sclerosis complex and Alzheimer's disease
Niere, F.; Uneri, A.; McArdle, C. J.; Cacheaux, L. P.; Reynoldson, C.; Penaranda, J.; Taylor, W. C.; Craft, S.; Keene, C. D.; Ma, T.; Raab-Graham, K. F.
10.1101/2020.08.26.267260 — neuroscience — Posted on 2021-12-03
3468 Synaptic Mechanisms of Top-Down Control in the Non-Lemniscal Inferior Colliculus
Oberle, H. M.; Ford, A. N.; Dileepkumar, D.; Czarny, J.; Apostolides, P. F.
10.1101/2021.07.26.453816 — neuroscience — Posted on 2021-12-03
3469 In vitro neurons learn and exhibit sentience when embodied in a simulated game-world
Kagan, B. J.; Kitchen, A. C.; Tran, N. T.; Parker, B. J.; Bhat, A.; Rollo, B.; Razi, A.; Friston, K.
10.1101/2021.12.02.471005 — synthetic biology — Posted on 2021-12-03
3472 The tiny, conserved zinc-finger protein GTSF1helps PIWI proteins achieve their full catalytic potential
Arif, A.; Bailey, S.; Izumi, N.; Anzelon, T. A.; Ozata, D. M.; Andersson, C.; Gainetdinov, I.; MacRae, I. J.; Tomari, Y.; Zamore, P. D.
10.1101/2021.05.04.442675 — biochemistry — Posted on 2021-12-03
3473 A spatiotemporally resolved single cell atlas of the Plasmodium liver stage
Afriat, A.; Zuzarte-Luis, V.; Bahar Halpern, K.; Buchauer, L.; Marques, S.; Lahree, A.; Amit, I.; Mota, M. M.; Itzkovitz, S.
10.1101/2021.12.03.471111 — genomics — Posted on 2021-12-03
3474 Retracing the evolution from antimicrobial to targeting peptides
Caspari, O. D.; Garrido, C.; Choquet, Y.; Wollman, F.-A.; Lafontaine, I.
10.1101/2021.12.03.471120 — evolutionary biology — Posted on 2021-12-03
3475 Secretory cells are the primary source of pIgR in small airways
Blackburn, J. B.; Schaff, J. A.; Gutor, S.; Du, R.-H.; Nichols, D.; Sherrill, T.; Gutierrez, A. J.; Xin, M. K.; Wickersham, N.; Zhang, Y.; Holtzman, M. J.; Ware, L. B.; Banovich, N. E.; Kropski, J. A.; Blackwell, T. S.; Richmond, B. W.
10.1101/2021.11.10.467794 — cell biology — Posted on 2021-12-03
3482 Single immunization with recombinant ACAM2000 vaccinia viruses expressing the spike and the nucleocapsid proteins protect hamsters against SARS-CoV-2 caused clinical disease
Cao, J.; Deschambault, Y.; Lynch, J.; Warner, B.; Tierney, K.; Huynh, D.; Vendramelli, R.; Tailor, N.; Booth, S.; Sajesh, B.; Frost, K.; LeBlanc, K.; Layne, C.; Lin, L.; Beniac, D.; Carpenter, M.; Safronetz, D.; Li, X.; Kobasa, D.
10.1101/2021.12.02.470987 — microbiology — Posted on 2021-12-03
3485 A wipe-based stool collection and preservation kit for microbiome community profiling
Hua, H.; Meydan, C.; Afshin, E.; Lili, L.; D'Adamo, C.; Dudley, J.; Price, N.; Zhang, B.; Mason, C.
10.1101/2021.12.03.471072 — microbiology — Posted on 2021-12-03
3488 Loss of Zfp335 triggers cGAS/STING-dependent apoptosis of post-β selection pre-T cells
Ratiu, J. J.; Wang, Q.; Mehta, N.; Harnois, M. J.; DiPalma, D.; Wellford, S.; Roy, S.; Contreras, A.; Wiest, D.; Zhuang, Y.
10.1101/2021.12.03.471158 — immunology — Posted on 2021-12-03
3491 LINE-1 activation in the cerebellum drives ataxia
Takahashi, T.; Kudo, E.; Song, E.; Carvalho, F.; Yasumoto, Y.; Kong, Y.; Park, A.; Stoiljkovic, M.; Gao, X.-B.; Shanabrough, M.; Szigeti-Buck, K.; Liu, Z.-W.; Zhang, Y.; Sulkowski, P.; Glazer, P.; Kaczmarek, L.; Horvath, T.; Iwasaki, A.
10.1101/2021.12.03.471151 — neuroscience — Posted on 2021-12-03
3493 Distinctive properties of cones in the retinal clock and the circadian system
Sandu, C.; Wongchitrat, P.; Mazzaro, N.; Jaeger, C.; Calligaro, H.; Mendoza, J.; Hicks, D.; Felder-Schmittbuhl, M.-P.
10.1101/2020.09.15.297879 — neuroscience — Posted on 2021-12-03
3494 Decoding the Information Structure Underlying the Neural Representation of Concepts
Fernandino, L.; Tong, J.-Q.; Conant, L. L.; Humphries, C. J.; Binder, J. R.
10.1101/2021.03.16.435524 — neuroscience — Posted on 2021-12-03
3496 Influence of sensory modality and control dynamics on human path integration
Stavropoulos, A.; Lakshminarasimhan, K. J.; Laurens, J.; Pitkow, X.; Angelaki, D.
10.1101/2020.09.21.307256 — neuroscience — Posted on 2021-12-03
3501 FACT-mediated maintenance of chromatin integrity during transcription is essential for viability of mammalian stem cells
Goswami, I.; Sandlesh, P.; Stablewski, A.; Safina, A.; Toshkov, I.; Magnitov, M.; Wang, J.; Gurova, K.
10.1101/2021.06.21.449309 — systems biology — Posted on 2021-12-03
3505 The high-resolution structure of cell membranes revealed by in situ cryo-electron tomography
Zhao, G.; Cheng, S.; Yu, Y.; Zou, T.; Wang, H.; Tao, C.; Bi, G.; Zhou, Z. H.; Wang, H.
10.1101/2021.12.03.471052 — biophysics — Posted on 2021-12-03
3510 The structure of HiSiaQM defines the architecture of tripartite ATP-independent periplasmic (TRAP) transporters
Peter, M. F.; Depping, P.; Schneberger, N.; Severi, E.; Gatterdam, K.; Tindall, S.; Durand, A.; Heinz, V.; Koenig, P. A.; Geyer, M.; Ziegler, C.; Thomas, G. H.; Hagelueken, G.
10.1101/2021.12.03.471092 — biochemistry — Posted on 2021-12-03
3514 Nanoscale structural organization and stoichiometry of the budding yeast kinetochore
Cieslinski, K.; Wu, Y.-L.; Nechyporenko, L.; Hoerner, S. J.; Conti, D.; Ries, J.
10.1101/2021.12.01.469648 — cell biology — Posted on 2021-12-03
3515 Metformin abrogates pathological TNF-α-producing B cells through mTOR-dependent metabolic reprogramming in polycystic ovary syndrome
Xiao, N.; Wang, J.; Wang, T.; Xiong, X.; Zhou, J.; Su, X.; Peng, J.; Yang, C.; Li, X.; Lin, G.; Lu, G.; Gong, F.; Cheng, L.
10.1101/2021.12.03.471141 — cell biology — Posted on 2021-12-03
3519 Multimodal Analyses of Stable Vitiligo Skin Identify Tissue Interactions That Control Disease Persistence
Shiu, J.; Zhang, L.; Lentsch, G.; Flesher, J.; Jin, S.; Polleys, C.; Jo, S. J.; Mizzoni, C.; Mobasher, P.; Kwan, J.; Rius Diaz, F.; Tromberg, B.; Georgakoudi, I.; Nie, Q.; Balu, M.; Ganesan, A.
10.1101/2021.12.03.470971 — molecular biology — Posted on 2021-12-03
3520 A dynamic antibacterial T6SS in Pantoea agglomerans pv. betae delivers a lysozyme-like effector to antagonize competitors
Carobbi, A.; Di Nepi, S.; Fridman, C. M.; Dar, Y.; Ben-Yaakov, R.; Barash, I.; Salomon, D.; Sessa, G.
10.1101/2021.12.03.471080 — microbiology — Posted on 2021-12-03
3521 Unconventional secretion of unglycosylated ORF8 is critical for the cytokine storm during SARS-CoV-2 infection
Lin, X.; Fu, B.; Xiong, Y.; Xing, N.; Xue, W.; Guo, D.; Y. Zaky, M.; Pavani, K. C.; Kunec, D.; Trimpert, J.; Wu, H.
10.1101/2021.12.03.471057 — microbiology — Posted on 2021-12-03
3522 An unusual trafficking domain in MSRP6 defines a complex needed for Maurer's clefts anchoring and maintenance in P. falciparum infected red blood cells
Blancke Soares, A.; Staecker, J.; Schwald, S.; Hoijmakers, W. A. M.; Metwally, N. G.; Schoeler, H.; Flemming, S.; Hoehn, K.; Froehlke, U.; Mesen-Ramirez, P.; Bergmann, B.; Khosh-Naucke, M.; Bruchhaus, I.; Bartfai, R.; Spielmann, T.
10.1101/2021.12.03.471078 — microbiology — Posted on 2021-12-03
3523 Characterization of the hepatitis E virus replicase
Metzger, K.; Cyrine, B.; Hervouet, K.; Alexandre, V.; Montpellier, C.; Saliou, J. M.; Ferrie, M.; Camuzet, C.; Rouille, Y.; Lecoeur, C.; Dubuisson, J.; Cocquerel, L.; Aliouat Denis, C. M.
10.1101/2021.12.03.471094 — microbiology — Posted on 2021-12-03
3524 Systems immune profiling of variant-specific vaccination against SARS-CoV-2
Peng, L.; Park, J.; Fang, Z.; Zhou, X.; Dong, M.; Xiong, Q.; Lin, C.; Chen, S.
10.1101/2021.12.02.471028 — immunology — Posted on 2021-12-03
3525 Secreted ORF8 is a pathogenic cause of severe Covid-19 and potentially targetable with select NLRP3 inhibitors
Wu, X.; Manske, M. K.; Ruan, G.; Nowakowski, K. E.; Abeykoon, J. P.; Tang, X.; Yu, Y.; Witter, T. L.; Taupin, V.; Paludo, J.; Ansell, S. M.; Badley, A. D.; Schellenberg, M.; Witzig, T. E.
10.1101/2021.12.02.470978 — immunology — Posted on 2021-12-03
3526 Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells
Huang, D.; Li, J.; Hu, F.; Weng, Q.; Wang, T.; Peng, H.; Wu, B.; Xia, C.; Wu, H.; Xiong, J.; Lin, J.; Lin, Y.; Wang, Y.; Zhang, Q.; Liu, X.; Liu, L.; Zheng, X.; Qiu, H.; Geng, Y.; Du, X.; Wang, L.; Hao, J.; Wang, J.
10.1101/2021.12.03.471069 — immunology — Posted on 2021-12-03
3528 SARS-CoV-2 wildlife surveillance in Ontario and Quebec, Canada
Greenhorn, J. E.; Kotwa, J. D.; Bowman, J.; Bruce, L.; Buchanan, T.; Buck, P. A.; Dibernardo, A.; Flockhart, L.; Gagnier, M.; Hou, A.; Jardine, C. M.; Lair, S.; Lindsay, L. R.; Masse, A.; Muchaal, P. K.; Nituch, L. A.; Sotto, A.; Stevens, B.; Yip, L.; Mubareka, S.
10.1101/2021.12.02.470924 — pathology — Posted on 2021-12-03
3534 ImaGene: A web-based software platform for tumor radiogenomic evaluation and reporting
Sukhadia, S. S.; Tyagi, A. K.; Venkatraman, V.; Mukherjee, P.; P, P. A.; Divate, M. D.; Gevaert, O.; Nagaraj, S. H.
10.1101/2021.12.02.470994 — bioinformatics — Posted on 2021-12-03
3538 Epigenetic and Transcriptional Dysregulation in CD4+ T cells of Patients with Atopic Dermatitis
Eapen, A.; Parameswaran, S.; Forney, C.; Edsall, L.; Miller, D.; Donmez, O.; Dunn, K.; Lu, X.; Granitto, M.; Rowden, H.; Magier, A.; Pujato, M.; Chen, X.; Kaufman, K.; Bernstein, D.; Devonshire, A.; Rothenbereg, M.; Weirauch, M.; Kottyan, L.
10.1101/2021.12.03.471059 — genomics — Posted on 2021-12-03
3539 Functional analyses of two novel LRRK2 pathogenic variants in familial Parkinson's disease
Coku, I.; Mutez, E.; Eddarkaoui, S.; Carrier, S.; Marchand, A.; Deldycke, C.; Goveas, L.; Baille, G.; Tir, M.; Magnez, R.; Thuru, X.; Vermeersch, G.; VANDENBERGHE, W.; BUEE, L.; DEFEBVRE, L.; SABLONNIERE, B.; CHARTIER-HARLIN, M.-C.; Taymans, J.-M.; HUIN, V.
10.1101/2021.12.03.470891 — genetics — Posted on 2021-12-03
3540 Performance of genetic imputation across commercial crop species
Thorn, S.; Whalen, A.; Kollers, S.; Gholami, M.; da Silva, H. S.; Wimmer, V.; Hickey, J. M.
10.1101/2021.12.01.470712 — genetics — Posted on 2021-12-03
3541 Genetic insights into the management and conservation of Arctic charr in North Wales
Beck, S. V.; Carvalho, G. R.; McCarthy, I.; Hanks, W.; Evans, R.; Edwards, R.; Taylor, M.; de Bruyn, M.
10.1101/2021.12.03.470319 — genetics — Posted on 2021-12-03
3542 RORA regulates neutrophil migration and activation in zebrafish
Hsu, A. Y.; Wang, T.; Syahirah, R.; Liu, S.; Li, K.; Zhang, W.; Wang, J.; Cao, Z.; Tian, S.; Matosevic, S.; Staiger, C. J.; Wan, J.; Deng, Q.
10.1101/2021.12.03.470833 — cell biology — Posted on 2021-12-03
3543 Loquacious Modulates Flaviviral RNA Replication in Mosquito Cells
Shivaprasad, S.; Weng, K.-F.; Ooi, Y. S.; Belk, J.; Carette, J. E.; Flynn, R.; Sarnow, P.
10.1101/2021.12.03.471060 — microbiology — Posted on 2021-12-03
3545 Interleukin-13 and its receptor are synaptic proteins involved in plasticity and neuroprotection
Shun, L.; olde Heuvel, F.; Rehman, R.; Li, Z.; Aousji, O.; Froehlich, A.; Zhang, W.; Conquest, A.; Woelfle, S.; Schoen, M.; O Meara, C.; Reinhardt, R. L.; Voehringer, D.; Kassubek, J.; Ludolph, A.; Huber-Lang, M.; Knoell, B.; Morganti-Kossmann, M. C.; Boeckers, T. M.; Roselli, F.
10.1101/2021.12.01.470746 — neuroscience — Posted on 2021-12-03
3550 Macaque-human differences in SARS-CoV-2 Spike antibody response elicited by vaccination or infection
Willcox, A.; Sung, K.; Garrett, M. E.; Galloway, J. G.; OConnor, M. A.; Erasmus, J. H.; Logue, J. K.; Hawman, D. W.; Chu, H. Y.; Hasenkrug, K. J.; Fuller, D. H.; Matsen, F. A.; Overbaugh, J.
10.1101/2021.12.01.470697 — immunology — Posted on 2021-12-03
3551 A public antibody class recognizes a novel S2 epitope exposed on open conformations of SARS-CoV-2 spike
Claireaux, M.; Caniels, T. G.; de Gast, M.; Han, J.; Guerra, D.; Kerster, G.; van Schaik, B. D.; Jongejan, A.; Schriek, A. I.; Grobben, M.; Brouwer, P. J.; van der Straten, K.; Aldon, Y.; Capella-Pujol, J.; Snitselaar, J. L.; Olijhoek, W.; Aartse, A.; Brinkkemper, M.; Bontjer, I.; Burger, J. A.; Poniman, M.; Bijl, T. P.; Torres, J. L.; Copps, J.; Martin, I. C.; de Taeye, S. W.; de Bree, G. J.; Ward, A. B.; Sliepen, K.; van Kampen, A. H.; Moerland, P. D.; Sanders, R. W.; van Gils, M. J.
10.1101/2021.12.01.470767 — immunology — Posted on 2021-12-03
3552 ScRNA-Seq study of neutrophils reveals vast heterogeneity and breadth of inflammatory responses in severe COVID-19 patients
Xu, J.; He, B.; Carver, K.; Vanheyningen, D.; Parkin, B.; Garmire, L.; Olszewski, M. A.; Deng, J. A.
10.1101/2021.12.01.470817 — immunology — Posted on 2021-12-03
3564 Neighbor-specific gene expression revealed from physically interacting cells during mouse embryonic development
Kim, J.; Rothov, M. M.; Liao, L.; Rhee, S.; Weng, G.; David, E.; Amit, I.; Hajkarim, M. C.; Brickman, J. M.; Won, K. J.
10.1101/2021.12.02.470916 — developmental biology — Posted on 2021-12-03
3566 Phage resistance accompanies reduced fitness of uropathogenic E. coli in the urinary environment
Zulk, J. J.; Clark, J. R.; Ottinger, S.; Ballard, M. B.; Mejia, M. E.; Mercado, V.; Heckmann, E. R.; Sanchez, B. C.; Trautner, B. W.; Maresso, A. W.; Patras, K. A.
10.1101/2021.12.02.471000 — microbiology — Posted on 2021-12-03
3572 In vitro neurons learn and exhibit sentience when embodied in a simulated game-world
Kagan, B. J.; Kitchen, A. C.; Trab, N. T.; Parker, B. J.; Bhat, A.; Rollo, B.; Razi, A.; Friston, K.
10.1101/2021.12.02.471005 — synthetic biology — Posted on 2021-12-03
3573 A Non-Canonical Function of Arabidopsis ERECTA Proteins in Gibberellin Signaling
Sarnowska, E.; Kubala, S.; Cwiek, P.; Sacharowski, S.; Oksinska, P.; Steciuk, J.; Zaborowska, M.; Szurmak, J. M.; Dubianski, R.; Maassen, A.; Stachowiak, M.; Huettel, B.; Ciesla, M.; Nowicka, K.; Rolicka, A. T.; Alseekh, S.; Bucior, E.; Franzen, R.; Klepacz, A.; Domagalska, M. A.; Amar, S.; Fernie, A. R.; Davis, S. J.; Sarnowski, T. J.
10.1101/2021.12.02.470991 — plant biology — Posted on 2021-12-03
3574 CV-containing vesicle budding from chloroplast inner envelope membrane is mediated by clathrin but inhibited by GAPC
Pan, T.; Liu, X. Y.; Ling, C. C.; Tang, Y. Y.; Tang, W.; Liu, Y.; Guo, L.; Kim, C.; Fang, J.; Lin, H. H.; Blumwald, E.; Wang, H. S.
10.1101/2021.12.02.470903 — plant biology — Posted on 2021-12-03
3575 Tumor Treating Fields Suppression of Ciliogenesis Enhances Temozolomide Toxicity
Shi, P.; Tian, J.; Ulm, B.; Mallinger, J.; Khoshbouei, H.; Deleyrolle, L.; Sarkisian, M. R.
10.1101/2021.12.02.470969 — cancer biology — Posted on 2021-12-03
3576 ABC Transporters are billion-year-old Maxwell Demons
Flatt, S.; Busiello, D. M.; Zamuner, S.; De Los Rios, P.
10.1101/2021.12.03.471046 — biophysics — Posted on 2021-12-03
3579 Fractal scaling of C. elegans behavior is shaped by insulin signaling
Arata, Y.; Shiga, I.; Ikeda, Y.; Kimura, H.; Jurica, P.; Kiyono, K.; Sako, Y.
10.1101/2021.12.02.471007 — animal behavior and cognition — Posted on 2021-12-03
3581 Epiphany: predicting Hi-C contact maps from 1D epigenomic signals
Yang, R.; Das, A.; Gao, V. R.; Karbalayghareh, A.; Noble, W. S.; Bilmes, J. A.; Leslie, C. S.
10.1101/2021.12.02.470663 — genomics — Posted on 2021-12-03
3583 UG/Abi: a highly diverse family of prokaryotic reverse transcriptases associated with defense functions
Mestre, M. R.; Gao, L.; Shah, S. A.; Lopez-Beltran, A.; Gonzalez-Delgado, A.; Martinez-Abarca, F.; Iranzo, J.; Redrejo-Rodriguez, M.; Zhang, F.; Toro, N.
10.1101/2021.12.02.470933 — evolutionary biology — Posted on 2021-12-03
3584 Historical biogeography of early diverging termite lineages (Isoptera: Teletisoptera)
Wang, M.; Hellemans, S.; Sobotnik, J.; Arora, J.; Bucek, A.; Sillam-Dusses, D.; Clitheroe, C.; Lu, T.; Lo, N.; Engel, M.; Roisin, Y.; Evans, T. A.; bourguignon, t.
10.1101/2021.12.02.471008 — evolutionary biology — Posted on 2021-12-03
3585 A chromosomal inversion may facilitate adaptation despite periodic gene flow in a freshwater fish
Thorstensen, M. J.; Euclide, P. T.; Jeffrey, J. D.; Shi, Y.; Treberg, J. R.; Watkinson, D. A.; Enders, E. C.; Larson, W. A.; Kobayashi, Y.; Jeffries, K.
10.1101/2021.12.02.470985 — evolutionary biology — Posted on 2021-12-03
3589 Zn2+ acts as a brake signal for axonal transport by directly inhibiting motor protein progression
Minckley, T. F.; Dischler, A. M.; Fudge, D. H.; Zadeh, E. G.; Li, W.-h.; Verhey, K.; Markus, S. M.; Qin, Y.
10.1101/2021.12.02.470968 — cell biology — Posted on 2021-12-03
3591 Synergistic collagen-condiment: Streptococcal collagen-like (Scl) protein in cell-adhesion and diabetic wound-closure matrix
Singh, R.; Choudhury, C.; Nambiyar, K.; Sharma, S.; Singh, L.; Bhatia, A.; Banerjee, D.; Das, A.; Chakraborti, A.
10.1101/2021.12.02.470992 — microbiology — Posted on 2021-12-03
3592 Lactococcus lactis sb. cremoris orchestrates signal events in the gut epithelium via TLR2 to promote tissue restitution
Naudin, C. R.; Owens, J. A.; Askew, L. C.; Khan, R. N.; Scharer, C. D.; Matthews, J. D.; Luo, L.; Kim, J.; Reedy, A. R.; Barbian, M. E.; Jones, R. M.
10.1101/2021.12.02.471025 — microbiology — Posted on 2021-12-03
3594 Age-elevated prostaglandin E2 enhances mortality to influenza infection
Chen, J.; Deng, J. C.; Zemans, R. L.; Zhang, M.; Peters-Golden, M.; Goldstein, D. R.
10.1101/2021.12.02.470775 — immunology — Posted on 2021-12-03
3595 Neutralization Fingerprinting Technology for Characterizing Polyclonal Antibody Responses to Dengue Vaccines
Raju, N.; Zhan, X.; Das, S.; Karwal, L.; Dean, H.; Crowe, J. E.; Carnahan, R. H.; Georgiev, I.
10.1101/2021.12.02.467518 — immunology — Posted on 2021-12-03
3597 Binary and analog variation of synapses between cortical pyramidal neurons
Dorkenwald, S.; Turner, N. L.; Macrina, T.; Lee, K.; Lu, R.; Wu, J.; Bodor, A. L.; Bleckert, A. A.; Brittain, D.; Kemnitz, N.; Silversmith, W. M.; Ih, D.; Zung, J.; Zlateski, A.; Tartavull, I.; Yu, S.-C.; Popovych, S.; Wong, W.; Castro, M.; Jordan, C.; Wilson, A. M.; Froudarakis, E.; Buchanan, J.; Takeno, M.; Torres, R.; Mahalingam, G.; Collman, F.; Schneider-Mizell, C.; Bumbarger, D. J.; Li, Y.; Becker, L.; Suckow, S.; Reimer, J.; Tolias, A. S.; da Costa, N. M.; Reid, R. C.; Seung, H. S.
10.1101/2019.12.29.890319 — neuroscience — Posted on 2021-12-03
3599 Specific plasticity loci and their synergism mediate operant conditioning
Momohara, Y.; Neveu, C. L.; Chen, H.-M.; Baxter, D. A.; Byrne, J. H.
10.1101/2021.12.02.470828 — neuroscience — Posted on 2021-12-03
3601 Sex-specific Stress and Behavioural Responses to Human Experimenters in Rats
Faraji, J.; Ambeskovic, M.; Sauter, N.; Toly, J.; Whitten, K.; Lopes, N. A.; Olson, D. M.; Metz, G. A. S.
10.1101/2021.12.01.470834 — neuroscience — Posted on 2021-12-03
3602 Assessing the impact of free-roaming dog population management through systems modelling
Smith, L. M.; Quinnell, R. J.; Goold, C. M.; Munteanu, A.; Hartmann, S.; Collins, L. M.
10.1101/2021.12.02.470957 — zoology — Posted on 2021-12-03
3603 Smart3-ATAC: a highly sensitive method for joint accessibility and full-length transcriptome analysis in single cells
Cheng, H.; Pui, H.-P.; Lentini, A.; Kolbeinsdottir, S.; Andrews, N.; Pei, Y.; Reinius, B.; Deng, Q.; Enge, M.
10.1101/2021.12.02.470912 — systems biology — Posted on 2021-12-03
3605 Self-confined expression in the Arabidopsis root stem cell niche
Mercadal, J.; Betegon-Putze, I.; Bosch, N.; Cano-Delgado, A.; Ibanes, M.
10.1101/2021.12.02.468941 — systems biology — Posted on 2021-12-03
3607 A stepwise route to domesticate rice by controlling seed shattering and panicle shape
Ishikawa, R.; Castillo, C. C.; Htun, T. M.; Numaguchi, K.; Inoue, K.; Oka, Y.; Ogasawara, M.; Sugiyama, S.; Takama, N.; Orn, C.; Inoue, C.; Nonomura, K.-i.; Allaby, R. G.; Fuller, D. Q.; Ishii, T.
10.1101/2021.12.02.470680 — plant biology — Posted on 2021-12-03
3608 A nuclear import pathway exploited by viroid RNAs
Ma, J.; Mudiyanselage, S. D. D.; Park, W. J.; Wang, M.; Takeda, R.; Liu, B.; Wang, Y.
10.1101/2021.12.02.470923 — plant biology — Posted on 2021-12-03
3611 Oxycodone decreases anxiety-like behavior in the elevated plus-maze test in male and female rats
Bruijnzeel, A.; Behnood-Rod, A.; Malphurs, W.; Chellian, R.; Caudle, R.; Febo, M.; Setlow, B.; Neubert, J.
10.1101/2021.12.02.470973 — pharmacology and toxicology — Posted on 2021-12-03
3613 The PNUTS-PAD domain recruits MYC to the PNUTS:PP1 phosphatase complex via the oncogenic MYC-MB0 region
Wei, Y.; Ahlner, A.; Redel, C.; Lemak, A.; Johansson-Akhe, I.; Houliston, S.; Kenney, T. M. G.; Tamachi, A.; Morad, V.; Duan, S.; Andrews, D. W.; Wallner, B.; Sunnerhagen, M.; Arrowsmith, C. H.; Penn, L. Z.
10.1101/2021.12.02.470928 — cancer biology — Posted on 2021-12-03
3615 Fast volumetric imaging with line-scan confocal microscopy by an electro-tunable lens
Mac, D. K.; Qureshi, M. M.; Na, M.; Chang, S.; Kwon, H.; Eom, T. J.; Je, H. S.; Kim, Y. R.; Chung, E.
10.1101/2021.12.01.470673 — bioengineering — Posted on 2021-12-03
3616 Miniature Structured Illumination Microscope for in vivo 3D Imaging of Brain Structures with Optical Sectioning
Supekar, O. D.; Sias, A.; Hansen, S. R.; Martinez, G.; Peet, G. C.; Peng, X.; Bright, V. M.; Hughes, E. G.; Restrepo, D.; Shepherd, D. P.; Welle, C. G.; Gopinath, J. T.; Gibson, E. A.
10.1101/2021.12.02.470995 — bioengineering — Posted on 2021-12-03
3618 Neoisoptera repetitively colonised Madagascar after the Middle Miocene climatic optimum
Wang, M.; Hellemans, S.; Bucek, A.; Kanao, T.; Arora, J.; Clitheroe, C.; Rafanomezantsoa, J.-J.; Fisher, B.; Scheffrahn, R.; Sillam-Dusses, D.; Roisin, Y.; Sobotnik, J.; bourguignon, t.
10.1101/2021.12.01.470872 — ecology — Posted on 2021-12-03
3620 Coupling adipose tissue architecture and metabolism via cytoophidia
Liu, J.; Zhang, Y.; Zhou, Y.; Wang, Q.-Q.; Ding, K.; Zhao, S.; Lu, P.; Liu, J.-L.
10.1101/2021.12.02.470854 — developmental biology — Posted on 2021-12-03
3624 LIFELONG CYTOMEGALOVIRUS AND EARLY-LIFE IRRADIATION SYNERGISTICALLY POTENTIATE AGE-RELATED DEFECTS IN RESPONSE TO VACCINATION AND INFECTION
Pugh, J. L.; Coplen, C. P.; Sukhina, A. S.; Uhrlaub, J. L.; Padilla-Torres, J. L.; Hayashi, T.; Nikolich-Zugich, J.
10.1101/2021.12.01.470812 — immunology — Posted on 2021-12-03
3625 Moving Beyond Processing and Analysis-Related Variation in Neuroscience
Li, X.; Ai, L.; Giavasis, S.; Jin, H.; Feczko, E.; Xu, T.; Clucas, J.; Franco, A.; Heinsfeld, A. S.; Adebimpe, A.; Vogelstein, J. T.; Yan, C.-G.; Esteban, O.; Poldrack, R. A.; Craddock, C.; Fair, D.; Satterthwaite, T.; Kiar, G.; Milham, M. P.
10.1101/2021.12.01.470790 — neuroscience — Posted on 2021-12-03
3626 Estimating muscle activation from EMG using deep learning-based dynamical systems models
Wimalasena, L. N.; Braun, J. F.; Keshtkaran, M. R.; Hofmann, D.; Gallego, J. A.; Alessandro, C.; Tresch, M. C.; Miller, L. E.; Pandarinath, C.
10.1101/2021.12.01.470827 — neuroscience — Posted on 2021-12-03
3628 Layer 1 NDNF+ interneurons control bilateral sensory processing in a layer-dependent manner
Karayannis, T.; Vighagen, R.; Gesuita, L.; Damilou, A.; Cavaccini, A.; Banterle, L.; Steenhuis, V.
10.1101/2021.12.02.470902 — neuroscience — Posted on 2021-12-03
3630 Mitochondrial control of microglial phagocytosis in Alzheimer's disease
Fairley, L. H.; Lai, K. O.; Wong, J. H.; Salvatore, A. V.; D'Agostino, G.; Wu, X.; Jayaraman, A.; Langley, S. R.; Ruedl, C. R.; Barron, A. M.
10.1101/2021.12.01.469111 — neuroscience — Posted on 2021-12-03
3633 Serum Amyloid A promotes Acetaminophen-induced liverinjury by damaging sinusoidal endothelial cell and exacerbating platelet aggregation in liver
You, K.; Wang, Y.; Chen, X.; Yang, Z.; Chen, Y.; Tan, S.; Tao, J.; Getachew, A.; Pan, T.; Xu, Y.; Zhuang, Y.; Yang, F.; Lin, X.; Li, Y.
10.1101/2021.12.01.470869 — pharmacology and toxicology — Posted on 2021-12-03
3642 Sex-dependent changes in murine striatal dopamine release, sleep, and behavior during spontaneous Δ-9-tetrahydrocannabinol abstinence
Kesner, A. J.; Mateo, Y.; Abrahao, K. P.; Ramos-Maciel, S.; Pava, M. J.; Gracias, A. L.; Paulsen, R. T.; Carlson, H. B.; Lovinger, D. M.
10.1101/2021.12.01.470765 — neuroscience — Posted on 2021-12-03
3644 Imaging Three-Dimensional Brain Organoid Architecture from Meso- to Nanoscale across Development
Rodriguez-Gatica, J. E.; Iefremova, V.; Sokhranyaeva, L.; Yeung, S. W. C. A.; Breitkreuz, Y.; Bruestle, O.; Schwarz, M. K.; Kubitscheck, U.
10.1101/2021.12.03.471084 — neuroscience — Posted on 2021-12-03
3649 Evaluation of the efficacy of simethicone in the abdominal ultrasound and pancreas evaluation on dogs
Garcia, L. F. C.; Grendel, V.; Rodacki, M.; Goncalves, M. M.; Cottar, B. H.; Albrecht, L.; Weber, S. H.; Tasqueti, U. I.
10.1101/2021.12.01.470744 — pharmacology and toxicology — Posted on 2021-12-03
3650 A 3D printable device allowing fast and reproducible longitudinal preparation of mouse intestines
DeLucia, B.; Samorezov, S.; Zangara, M. T.; Markley, R. L.; Osborn, L. J.; Schultz, K. B.; McDonald, C.; Claesen, J.
10.1101/2021.12.01.470784 — pathology — Posted on 2021-12-03
3652 A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables
Hecker, J.; Prokopenko, D.; Moll, M.; Lee, S.; Kim, W.; Qiao, D.; Voorhies, K.; Kim, W.; Vansteelandt, S.; Hobbs, B. D.; Cho, M. H.; Silverman, E. K.; Lutz, S. M.; DeMeo, D. L.; Weiss, S. T.; Lange, C.
10.1101/2021.12.01.469907 — bioinformatics — Posted on 2021-12-03
3653 No part gets left behind: Tiled nanopore sequencing of whole ASFV genomes stitched together using Lilo
Warr, A.; Newman, C.; Craig, N.; Vendele, I.; Pilare, R.; Cariazo Cruz, L.; Galase Barangan, T.; Morales, R. G.; Opriessnig, T. I.; Venturina, V.; Mananggit, M. R.; Lycett, S.; Domingo, C. Y. J.; Tait-Burkard, C.
10.1101/2021.12.01.470769 — bioinformatics — Posted on 2021-12-03
3656 Glucocorticoids Unmask Silent Non-Coding Genetic Risk Variants for Common Diseases
Nguyen, T. T. L.; Gao, H.; Liu, D.; Ye, Z.; Lee, J.-H.; Shi, G.-x.; Copenhaver, K.; Zhang, L.; Wei, L.; Yu, J.; Zhang, C.; Li, H.; Wang, L.; Ordog, T.; Weinshilboum, R. M.
10.1101/2021.12.01.470787 — genomics — Posted on 2021-12-03
3657 Folate pathway metabolites are altered in the plasma of subjects with Down syndrome: relation to chromosomal dosage
Vione, B.; Locatelli, C.; Zavaroni, G.; Piano, A.; La Rocca, G.; Caracausi, M.; Vitale, L.; Piovesan, A.; Gori, C.; Pirazzoli, G.; Strippoli, P.; Cocchi, G.; Ramacieri, G.; Pelleri, M. C.; Antonaros, F.
10.1101/2021.11.30.470411 — genetics — Posted on 2021-12-03
3661 Sentinel2GlobalLULC: A deep-learning-ready Sentinel-2 RGB image dataset for global land use/cover mapping
Benhammou, y.; Segura, D. A.; Guirado, E.; Khaldi, R.; Achchab, B.; Herrera, F.; Tabik, S.
10.1101/2021.12.01.470768 — ecology — Posted on 2021-12-03
3663 Single-cell Multiomics Reveals Clonal T-cell Expansions and Exhaustion in Blastic Plasmacytoid Dendritic Cell Neoplasm
DePasquale, E. A.; Ssozi, D.; Ainciburu, M.; Good, J.; Noel, J.; Villanueva, M.; Couturier, C.; Shalek, A. K.; Aranki, S. F.; Mallidi, H. R.; Griffin, G. K.; Lane, A. A.; van Galen, P.
10.1101/2021.12.01.470599 — immunology — Posted on 2021-12-03
3665 Cerebrovascular insulin receptors are defective in Alzheimer's disease
Leclerc, M.; Bourassa, P.; Tremblay, C.; Caron, V.; Sugere, C.; Emond, V.; Bennett, D. A.; Calon, F.
10.1101/2021.12.01.470582 — neuroscience — Posted on 2021-12-03
3667 The Evolutionary Dynamics of Hyperparasites
Northrup, G. R.; Parratt, S. R.; Rozins, C.; Laine, A.-L.; Boots, M.
10.1101/2021.12.01.470853 — evolutionary biology — Posted on 2021-12-03
3670 The functional evolution of termite gut microbiota
Arora, J.; Kinjo, Y.; Sobotnik, J.; Bucek, A.; Clitheroe, C.; Stiblik, P.; Roisin, Y.; Zifcakova, L.; Park, Y. C.; Kim, K. Y.; Sillam-Dusses, D.; Herve, V.; Lo, N.; Tokuda, G.; Brune, A.; bourguignon, t.
10.1101/2021.12.01.470864 — evolutionary biology — Posted on 2021-12-03
3673 Genomic hallmarks of cellular dormancy in cancer and therapeutic implications
Wiecek, A. J.; Cutty, S. J.; Kornai, D.; Parreno-Centeno, M.; Gourmet, L. E.; Malagoli Tagliazucchi, G.; Jacobson, D. H.; Zhang, P.; Xiong, L.; Bond, G. L.; Barr, A. R.; Secrier, M.
10.1101/2021.11.12.468410 — cancer biology — Posted on 2021-12-03
3674 The molecular logic of synaptic wiring at the single cell level
Lohmann, I.; Velten, J.; Agarwal, R.; van Nierop y Sanchez, P.; Bognar, L.; Paulsen, M.; Velten, L.
10.1101/2020.11.30.402057 — developmental biology — Posted on 2021-12-03
3675 Population dynamics underlying associative learning in the dorsal and ventral hippocampus
Biane, J. S.; Ladow, M. A.; Stefanini, F.; Boddu, S. P.; Fan, A.; Hassan, S.; Dundar, N.; Apodaca-Montano, D. L.; Woods, N. I.; Khierbek, M. A.
10.1101/2021.11.16.468862 — neuroscience — Posted on 2021-12-03
3679 Local mechanical stimuli shape tissue growth in vertebrate joint morphogenesis
Comellas, E.; Farkas, J. E.; Kleinberg, G.; Lloyd, K.; Mueller, T.; Duerr, T. J.; Munoz, J. J.; Monaghan, J. R.; Shefelbine, S. J.
10.1101/2021.08.28.458034 — developmental biology — Posted on 2021-12-03
3681 Predicting the functional effects of voltage-gated potassium channel missense variants with multi-task learning
Bosselmann, C.; Hedrich, U. B. S.; Müller, P.; Sonnenberg, L.; Parthasarathy, S.; Helbig, I.; Lerche, H.; Pfeifer, N.
10.1101/2021.12.02.470894 — bioinformatics — Posted on 2021-12-03
3683 FIRST REPORT OF HALOBACTERIA DOMINANCE IN A TROPICAL CAVE MICROBIOME
Paula, C. C. P. d.; Sirova, D.; Sarmento, H. P.; Fernandes, C. C.; Kishi, L. T.; Bichuette, M. E.; Seleghim, M. H. R.
10.1101/2021.12.02.470950 — microbiology — Posted on 2021-12-02
3684 cacna2d3, a voltage-gated calcium channel subunit, functions in vertebrate habituation learning and the startle sensitivity threshold
Santistevan, N. J.; Nelson, J. C.; Ortiz, E. A.; Miller, A. H.; Halabi, D. K.; Sippl, Z. A.; Granato, M.; Grinblat, Y.
10.1101/2021.12.02.470952 — neuroscience — Posted on 2021-12-02
3688 A 3'-end capture sequencing method for high-throughput targeted gene expression profiling
de Bony, E. J.; Gysens, F.; Yigit, N.; Anckaert, J.; Everaert, C.; Vanden Eynde, E.; Verniers, K.; Van Snippenberg, W.; Trypsteen, W.; Mestdagh, P.
10.1101/2021.12.02.470897 — genomics — Posted on 2021-12-02
3689 Detection of allele-specific expression in spatial transcriptomics with spASE
Zou, L. S.; Zhao, T.; Cable, D. M.; Murray, E.; Aryee, M. J.; Chen, F.; Irizarry, R. A.
10.1101/2021.12.01.470861 — genomics — Posted on 2021-12-02
3691 Transient dopamine neuron activity precedes and encodes the vigor of contralateral movements
Mendonca, M. D.; Alves da Silva, J.; Hernandez, L. F.; Castela, I.; Obeso, J.; Costa, R. M.
10.1101/2021.04.20.440527 — neuroscience — Posted on 2021-12-02
3692 ACTIN Anchors the Highly Oligomeric DRP1 at Mitochondria-Sarcoplasmic Reticulum Contact Sites in Adult Murine Heart: Its Functional Implication
Fernandez Sanz, C.; De la Fuente Perez, S.; Nichtova, Z.; Yuan, Y.; Lanvermann, S.; Tsai, H.-Y.; Ferderico, M.; Xin, Y.; Csordas, G.; Wang, W.; Mourier, A.; Sheu, S.-S.
10.1101/2021.11.29.470468 — physiology — Posted on 2021-12-02
3695 Federated analysis of BRCA1 and BRCA2 variation in a Japanese cohort
Casaletto, J.; Parsons, M.; Markello, C.; Iwasaki, Y.; Momozawa, Y.; Spurdle, A. B.; Cline, M.
10.1101/2021.06.04.447169 — bioinformatics — Posted on 2021-12-02
3696 Structural Basis for an Unprecedented Enzymatic Alkylation in Cylindrocyclophane Biosynthesis
Braffman, N. R.; Ruskoski, T. B.; Davis, K. M.; Glasser, N. R.; Johnson, C.; Okafor, D.; Boal, A. K.; Balskus, E. P.
10.1101/2021.12.02.470901 — biochemistry — Posted on 2021-12-02
3698 HSC-independent definitive hematopoietic cells persist into adult life
Kobayashi, M.; Wei, H.; Yamanashi, T.; Shih, D. J.; Portilho, N. A.; Cornelius, S.; Valiente, N.; Nishida, C.; Zheng, W. J.; Kang, J.; Seita, J.; Wu, J.; Yoshimoto, M.
10.1101/2021.12.02.468909 — developmental biology — Posted on 2021-12-02
3699 MAL suppresses OSCC tumorigenesis by maintaining epithelial cell differentiation
Chen, W.; Zhu, X.; Liu, Z.; Qi, S.; Zou, X.; Lu, T.; Ke, X.; Qin, X.; Wang, X.; Yan, M.; Xu, Q.; Zhang, J.; Wang, X.; Zhang, Z.; Cao, W.; Wu, X.
10.1101/2021.12.01.470749 — cell biology — Posted on 2021-12-02
3700 Label-free characterisation of amyloids and alpha-Synuclein polymorphs by exploiting their intrinsic fluorescence property
Chung, C. W.; Stephens, A. D.; Ward, E.; Feng, Y.; Davis, M. J.; Kaminski, C. F.; Kaminski Schierle, G. S.
10.1101/2021.11.30.470691 — molecular biology — Posted on 2021-12-02
3711 Wide spectrum of neuronal and network phenotypes in human stem cell-derived excitatory neurons with Rett syndrome-associated MECP2 mutations
Mok, R. S.; Zhang, W.-B.; Sheikh, T. I.; Pradeepan, K.; Fernandes, I. R.; DeJong, L. C.; Benigno, G.; Hildebrandt, M. R.; Mufteev, M.; Rodrigues, D. C.; Wei, W.; Piekna, A.; Liu, J.; Muotri, A. R.; Vincent, J. B.; Muller, L.; Martinez-Trujillo, J. C.; Salter, M. W.; Ellis, J.
10.1101/2020.07.12.189621 — neuroscience — Posted on 2021-12-02
3712 Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing
Schink, S. J.; Christodoulou, D.; Mukherjee, A.; Athaide, E.; Brunner, V.; Fuhrer, T.; Bradshaw, G. A.; Sauer, U.; Basan, M.
10.1101/2021.05.07.443112 — systems biology — Posted on 2021-12-02
3715 MDR1 Drug Efflux Pump Promotes Intrinsic and Acquired Resistance to PROTACs in Cancer Cells
Kurimchak, A. M.; Herrera-Montavez, C.; Montserrat-Sangra, S.; Araiza-Olivera, D.; Hu, J.; Jin, J.; Duncan, J. S.
10.1101/2021.12.02.470920 — cancer biology — Posted on 2021-12-02
3717 The SPICA Coarse-Grained Force Field for Proteins and Peptides
Kawamoto, S.; Liu, H.; Seo, S.; Miyazaki, Y.; Dixit, M.; DeVane, R.; MacDermaid, C.; Fiorin, G.; Klein, M. L.; Shinoda, W.
10.1101/2021.12.01.470839 — biophysics — Posted on 2021-12-02
3720 Cationic inhalable particles for enhanced drug delivery to M. tuberculosis infected macrophages
Sharma, P. R.; Dravid, A. A.; Chakravarthy, Y. K.; Gupta, V. K.; Jeyasankar, S.; Goswami, A.; Agarwal, R.
10.1101/2021.12.01.470866 — bioengineering — Posted on 2021-12-02
3723 The HIV-1 capsid core is an opportunistic nuclear import receptor
Xue, G.; Yu, H. J.; Goh, S. L.; Gres, A. T.; Guney, M. H.; Sarafianos, S. G.; Luban, J.; KewalRamani, V. N.
10.1101/2021.12.02.470925 — cell biology — Posted on 2021-12-02
3725 Global inflammatory response in in vitro organ cultured testes using single-cell RNA-sequencing
Suzuki, T.; Abe, T.; Yabukami, H.; Ikegaya, M.; Suzuki, K.; Sato, T.; Komeya, M.; Ogawa, T.
10.1101/2021.12.01.470873 — molecular biology — Posted on 2021-12-02
3726 An ecological perspective on microbial genes of unknown function in soil
Holland-Moritz, H.; Vanni, C.; Fernandez-Guerra, A.; Bissett, A.; Fierer, N.
10.1101/2021.12.02.470747 — microbiology — Posted on 2021-12-02
3734 Polycomb Group Ring Finger Protein 6 suppresses Myc-induced lymphomagenesis
Tanaskovic, N.; Dalsass, M.; Ceccotti, G.; Filipuzzi, M.; Verrecchia, A.; Nicoli, P.; Doni, M.; Olivero, D.; Pasini, D.; Koseki, H.; Sabo, A.; Bisso, A.; Amati, B.
10.1101/2021.12.02.470967 — cancer biology — Posted on 2021-12-02
3738 Structural basis of dynamic P5CS filaments
Zhong, J.; Guo, C.-J.; Zhou, X.; Chang, C.-C.; Yin, B.; Zhang, T.; Hu, H.-H.; Lu, G.-M.; Liu, J.-L.
10.1101/2021.12.02.470899 — biochemistry — Posted on 2021-12-02
3739 Draft genome of the Brazilian railroad worm Phrixothrix hirtus E.Olivier (Phengodidae: Coleoptera)
Amaral, D. T.; Mitani, Y.; BONATELLI, I. A. D. S.; Cerri, R.; Ohmiya, Y.; Viviani, V.
10.1101/2021.12.01.470735 — genomics — Posted on 2021-12-02
3740 Clinical implementation of single-cell RNA sequencing using liver fine needle aspirate tissue sampling and centralized processing captures compartment specific immuno-diversity
Genshaft, A. S.; Subudhi, S.; Keo, A.; Sanchez Vasquez, J. D.; Conceicao-Neto, N.; Mahamed, D.; Boeijen, L. L.; Alatrakchi, N.; Oetheimer, C.; Vilme, M.; Drake, R.; Fleming, I.; Tran, N.; Tzouanas, C.; Joseph-Chazan, J.; Villanueva, M. A.; van de Werken, H. J. G.; van Oord, G. W.; Groothuismink, Z. M. A.; Beudeker, B. J.; Osmani, Z.; Nkongolo, S.; Mehrotra, A.; Feld, J.; Chung, R. T.; de Knegt, R. J.; Janssen, H. L. A.; Aerssens, J.; Bollekens, J.; Hacohen, N.; Lauer, G. M.; Boonstra, A.; Shalek, A. K.; Gehring, A.
10.1101/2021.11.30.470634 — immunology — Posted on 2021-12-02
3741 Benchmarking Geometric Deep Learning for Cortical Segmentation and Neurodevelopmental Phenotype Prediction
Fawaz, A.; Williams, L. Z. J.; Alansary, A.; Bass, C.; Gopinath, K.; Da Silva, M.; Dahan, S.; Adamson, C. L.; Alexander, B.; Thompson, D.; Ball, G.; Desrosiers, C.; Lombaert, H.; Rueckert, D.; Edwards, A. D.; Robinson, E. C.
10.1101/2021.12.01.470730 — neuroscience — Posted on 2021-12-02
3743 Mapping lesion, structural disconnection, and functional disconnection to symptoms in semantic aphasia
Souter, N. E.; Wang, X.; Thompson, H.; Krieger-Redwood, K.; Halai, A.; Lambon Ralph, M.; Thiebaut de Schotten, M.; Jefferies, E.
10.1101/2021.12.01.470605 — neuroscience — Posted on 2021-12-02
3747 A new protocol for speed vernalisation of winter cereals
Cha, J.-K.; O'Connor, K.; Alahmad, S.; Lee, J.-H.; Dinglasan, E.; Park, H.; Lee, S.-M.; Hirsz, D.; Kwon, S.-W.; Kwon, Y.; Kim, K.-M.; Ko, J.-M.; Hickey, L.; Shin, D.; Dixon, L.
10.1101/2021.12.01.470717 — plant biology — Posted on 2021-12-02
3751 FIRST REPORT OF HALOBACTERIA DOMINANCE IN A TROPICAL CAVE MICROBIOME
Paula, C. C. P. d.; Sirova, D.; Sarmento, H. P.; Fernandes, C. C.; Kishi, L. T.; Bichuette, M. E.; Seleghim, M. H. R.
10.1101/2021.12.02.470950 — microbiology — Posted on 2021-12-02
3752 ANXA2 enhances virus replication through negatively regulating cGAS-STING and RLRs2 mediated signal pathway
li, h.; mengdi, x.; hongyang, l.; zhaoxia, z.; chunying, f.; kunli, z.; xiaohong, l.; guangqiang, y.; qiongqiong, z.; changyao, l.; changjiang, w.
10.1101/2021.12.01.470696 — immunology — Posted on 2021-12-02
3755 Correspondence between gene expression and neurotransmitter receptor and transporter density in the human brain
Hansen, J. Y.; Markello, R. D.; Tuominen, L.; Norgaard, M.; Kuzmin, E.; Palomero-Gallagher, N.; Dagher, A.; Misic, B.
10.1101/2021.11.30.469876 — neuroscience — Posted on 2021-12-02
3756 Rapid volumetric brain changes after acute psychosocial stress
Uhlig, M.; Reinelt, J. D.; Lauckner, M.; Schaare, H. L.; Kumral, D.; Mildner, T.; Babayan, A.; Engert, V.; Villringer, A.; Gaebler, M.
10.1101/2021.12.01.470604 — neuroscience — Posted on 2021-12-02
3759 A single-cell transcriptomic landscape of innate and adaptive intratumoral immunity in triple negative breast cancer during chemo- and immunotherapies
Carpen, L.; Falvo, P.; Orecchioni, S.; Mitola, G.; Hillje, R.; Mazzara, S.; Mancuso, P.; Pileri, S.; Raveane, A.; Bertolini, F.
10.1101/2021.12.01.470716 — cancer biology — Posted on 2021-12-02
3761 Physics Augmented U-Net: A High-Frequency Aware Generative Prior for Microscopy
Pradeepkumar, J.; Anandakumar, M.; Kugathasan, V.; Seeber, A.; Wadduwage, D. N.
10.1101/2021.12.01.470743 — bioinformatics — Posted on 2021-12-02
3763 Molecular chaperone ability to inhibit amyloid-derived neurotoxicity, but not amorphous protein aggregation, depends on a conserved pH-sensitive Asp residue
Chen, G.; Andrade-Talavera, Y.; Zhong, X.; Hassan, S.; Biverstal, H.; Poska, H.; Abelein, A.; Leppert, A.; Kronqvist, N.; Rising, A.; Hebert, H.; J.B. Koeck, P.; Fisahn, A.; Johansson, J.
10.1101/2021.12.01.470723 — biochemistry — Posted on 2021-12-02
3767 Maternal parity affects Day 8 embryo gene expression in old mares
Derisoud, E.; Jouneau, L.; Gourtay, C.; Margat, A.; Archilla, C.; Jaszczyszyn, Y.; Legendre, R.; Daniel, N.; Peynot, N.; Dahirel, M.; Briot, L.; De geoffroy, F.; Duranthon, V.; Chavatte-Palmer, P.
10.1101/2021.12.01.470709 — developmental biology — Posted on 2021-12-02
3768 Biochemical propensity mapping for structural and functional anatomy of importin α IBB domain
Jibiki, K.; Liu, M.; Chaosen, L.; Kodama, T. S.; Kojima, C.; Fujiwara, T.; Yasuhara, N.
10.1101/2021.10.25.465662 — cell biology — Posted on 2021-12-02
3769 Tissue-wide coordination of calcium signaling regulates the epithelial stem cell pool during homeostasis
Moore, J. L.; Gao, F.; Matte-Martone, C.; Du, S.; Lathrop, E.; Ganesan, S.; Shao, L.; Bhaskar, D.; Cox, A.; Hendry, C. E.; Rieck, B. A.; Krishnaswamy, S.; Greco, V.
10.1101/2021.10.12.464066 — cell biology — Posted on 2021-12-02
3770 AraC binds the p75NTR transmembrane domain to induce neurodegeneration in mature neurons.
Lopes Rodrigues, V. S.; Boxy, P.; Sim, E.; Park, D. I.; Andersson, A.; Fernandez-Suarez, D.; Carbonell, J.; Nykjaer, A.; Kisiswa, L.
10.1101/2021.12.01.470721 — cell biology — Posted on 2021-12-02
3771 Unraveling a Bacterial Starvation Response Through the Direct Targets of a Starvation-Induced Transcriptional Activator
Ma, M.; Li, T.; Lemon, D. J.; Caro, E. A.; Ritchie, L. J.; Ryan, C.; Spearing, V. M.; Welch, R. D.; Garza, A.; Murphy, K. A.
10.1101/2021.11.28.470282 — microbiology — Posted on 2021-12-02
3774 Endogenous but not sensory-driven activity controls migration, morphogenesis and survival of adult-born neurons in the mouse olfactory bulb
Li, K.; Figarella, K.; Su, X.; Kovalchuk, Y.; Gorzolka, J.; Neher, J.; Mojtahedi, N.; Casadei, N.; Hedrich-Klimosch, U.; Garaschuk, O.
10.1101/2021.04.21.440775 — neuroscience — Posted on 2021-12-02
3778 Dynamic Resting State Motor Network Connectivity of Neurotypical Children, the Groundwork for Network-Guided Therapy in Childhood Movement Disorders
Sussman, B. L.; Wyckoff, S. N.; Fine, J. M.; Heim, J.; Wilfong, A. A.; Adelson, P. D.; Kruer, M. C.; Boerwinkle, V. L.
10.1101/2021.11.30.470606 — neuroscience — Posted on 2021-12-02
3784 Socioeconomics drive population change in the world's largest carnivores
Johnson, T. F.; Isaac, N. J. B.; Paviolo, A.; Gonzalez-Suarez, M.
10.1101/2021.11.30.470341 — ecology — Posted on 2021-12-02
3785 SARS-CoV-2 Delta derivatives impact on neutralization of Covishield recipient sera
Sahay, R.; Patil, D. Y.; Sapkal, G. N.; Deshpande, G. R.; Shete, A. M.; Nyayanit, D.; Kumar, S.; Dutta, S.; Yadav, P. D.
10.1101/2021.11.30.470521 — molecular biology — Posted on 2021-12-02
3786 TOPOVIBL-REC114 interaction regulates meiotic DNA double-strand breaks
Nore, A.; Juarez-Martinez, A. B.; Clement, J. A.; Brun, C.; Diagouraga, B.; Grey, C.; Bourbon, H.-M.; Kadlec, J.; Robert, T.; de Massy, B.
10.1101/2021.11.30.470517 — molecular biology — Posted on 2021-12-02
3789 Genomic architecture controls spatial structuring in Amazonian birds
Thom, G.; Moreira, L. R.; Batista, R.; Gehara, M.; Aleixo, A.; Smith, B. T.
10.1101/2021.12.01.470789 — genomics — Posted on 2021-12-02
3790 Input-specific control of interneuron numbers in nascent striatal networks
Sreenivasan, V.; Serafeimidou-Pouliou, E.; Exposito-Alonso, D.; Bercsenyi, K.; Bernard, C.; Bae, S.-E.; Oozeer, F.; Hanusz-Godoy, A.; Edwards, R.; Marin, O.
10.1101/2021.12.01.470575 — neuroscience — Posted on 2021-12-02
3791 Distributed processing for action control by prelimbic circuits targeting anterior-posterior dorsal striatal subregions.
Choi, K.; Piasini, E.; Vargas, L. C.; Henderson, N. T.; Hernandez, E. D.; Subramaniyan, M.; Gerfen, C. R.; Fuccillo, M. V.
10.1101/2021.12.01.469698 — neuroscience — Posted on 2021-12-02
3792 A temporal sequence of thalamic activity unfolds at transitions in behavioral arousal state
Setzer, B.; Fultz, N. E.; Gomez, D. E. P.; Williams, S. D.; Bonmassar, G.; Polimeni, J. R.; Lewis, L. D.
10.1101/2021.12.01.470627 — neuroscience — Posted on 2021-12-02
3794 Combining Plasma Extracellular Vesicle Let-7b-5p, miR-184 and Circulating miR-22-3p Levels for NSCLC Diagnosis and Drug Resistance Prediction
Vadla, G. P.; Dhagat, B.; Garcia, A.; Perez, G.; Ahmad, V.; Patterson, N.; Manjunath, Y.; Kaifi, J.; Li, G.; Chabu, C. Y.
10.1101/2021.08.15.456411 — cancer biology — Posted on 2021-12-01
3795 Cytosolic EZH2-IMPDH2 complexes regulate melanoma progression via GTP
Kuser Abali, G.; Noguchi, F.; Szeto, P.; Zhang, Y.; Huang, C.; Barlow, C. K.; Pomilio, G.; Chew, C.; Masoumi Moghaddam, S.; Zhao, P.; Andrews, M.; Leece, I.; Cheung, J. G.; Ameratunga, M.; Wong, N. C.; Schittenhelm, R. B.; Wei, A.; Shackleton, M.
10.1101/2021.11.02.467024 — cancer biology — Posted on 2021-12-01
3797 Genome-wide analysis of DNA methylation reveals selection signatures of the grass carp during domestication
Yu, E.; Li, Y.; Fu, B.; Zhang, J.; Xie, J.; Wang, G.; Tian, J.; Xia, Y.; Li, H.; Jiang, P.
10.1101/2021.11.04.467282 — genetics — Posted on 2021-12-01
3800 Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism
Romitti, M.; de Faria da Fonseca, B.; Doumont, G.; Gillotay, P.; Tourneur, A.; Eski, S. E.; Van Simaeys, G.; Chomette, L.; Lasolle, h.; Monestier, O.; Figini Kasprzyk, D.; Detours, V.; Singh, S. P.; Goldman, S.; Refetoff, S. P.; Costagliola, S.
10.1101/2021.12.01.470729 — developmental biology — Posted on 2021-12-01
3801 T Cell Receptor Beta Germline Variability is Revealed by Inference From Repertoire Data
Omer, A.; Peres, A.; Rodrigues, O. L.; Watson, C. T.; Lees, W.; Polak, P.; Collins, A. M.; Yaari, G.
10.1101/2021.05.17.444409 — immunology — Posted on 2021-12-01
3803 Purkinje Cell Activity in Medial and Lateral Cerebellum During Suppression of Voluntary Eye Movements in Rhesus Macaques
Avila, E.; Flierman, N.; Holland, P. J.; Roelfsema, P. R.; Frens, M. A.; Badura, A.; De Zeeuw, C. I.
10.1101/2021.03.26.437236 — neuroscience — Posted on 2021-12-01
3804 Differential richness inference for 16S rRNA marker gene surveys
Kumar, M. S.; Slud, E. V.; Hehnly, C.; Zhang, L.; Broach, J.; Irizarry, R. A.; Schiff, S. J.; Paulson, J. N.
10.1101/2021.11.07.467583 — bioinformatics — Posted on 2021-12-01
3805 Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity
Kouba, T.; Vogel, D.; Thorkelsson, S. R.; Quemin, E. R. J.; Williams, H. M.; Milewski, M.; Busch, C.; Guenther, S.; Gruenewald, K.; Rosenthal, M.; Cusack, S.
10.1101/2021.06.24.449696 — biochemistry — Posted on 2021-12-01
3806 Fatigue Metabolites of Large Yellow Croaker and Construction of Swimming Model
Chai, R.; Yin, H.; Huo, R.; Shui, X.; Wang, H.; Huang, L.; Wang, P.; Heng YinRunming Huo Xiaomei ShuiHanying WangLing HuangPing Wang,
10.1101/2021.12.01.470794 — animal behavior and cognition — Posted on 2021-12-01
3809 The dual function monoclonal antibodies VIR-7831 and VIR-7832 demonstrate potent in vitro and in vivo activity against SARS-CoV-2
Cathcart, A. L.; Havenar-Daughton, C.; Lempp, F. A.; Ma, D.; Schmid, M.; Agostini, M. L.; Guarino, B.; Di iulio, J.; Rosen, L.; Tucker, H.; Dillen, J.; Subramanian, S.; Sloan, B.; Bianchi, S.; Wojcechowskyj, J.; Zhou, J.; Kaiser, H.; Chase, A.; Lauron, E.; Montiel-Ruiz, M.; Spreafico, R.; Noack, J.; Czudnochowski, N.; Sahakyan, A.; Pinto, D.; Saliba, C.; Delotta, E.; Park, A.; Cameroni, E.; Ledoux, S.; Werts, A.; Colas, C.; Soriaga, L.; Telenti, A.; Purcell, L. A.; Hwang, S.; Snell, G.; Virgin, H. W.; Corti, D.; Hebner, C. M.
10.1101/2021.03.09.434607 — immunology — Posted on 2021-12-01
3810 Identification of CD4+ Sub-population of Resident Cardiac Fibroblasts Linked to Myocardial Fibrosis
Siamwala, J. H.; Pagano, F.; Dubielecka, P. M.; Zhao, A.; Chen, S.; Granston, H.; Rounds, S.; Sadayappan, S.; Gilbert, R. J.
10.1101/2021.02.26.433023 — immunology — Posted on 2021-12-01
3816 Mathematical Relationships between Spinal Motoneuron Properties
Caillet, A. H. D.; Phillips, A. T. M.; Farina, D.; Modenese, L.
10.1101/2021.08.05.455188 — neuroscience — Posted on 2021-12-01
3818 Integrative analysis reveals aged clonal B cells, microenvironment and c-Myc activation in the origin of age-related lymphoma
Shindyapina, A. V.; Castro, J. P.; Barbieri, A.; Strelkova, O. S.; Paulo, J. A.; Kerepesi, C.; Petrashen, A. P.; Mariotti, M.; Meer, M.; Hu, Y.; Karamyshev, A.; Losyev, G.; Indzhykulian, A. A.; Gygi, S. P.; Sedivy, J. M.; Manis, J. P.; Gladyshev, V. N.
10.1101/2021.02.23.432500 — cancer biology — Posted on 2021-12-01
3823 Overexpression of NDR1 Leads to Pathogen Resistance at Elevated Temperatures
Samaradivakara, S.; Chen, H.; Lu, Y.-J.; Li, P.; Kim, Y. S.; Tsuda, K.; Mine, A.; Day, B.
10.1101/2021.12.01.470751 — plant biology — Posted on 2021-12-01
3824 CURT1A and CURT1C mediate distinct stages of plastid conversion in Arabidopsis
Liang, Z.; Yeung, W.-T.; Mai, K. K.; Ma, J.; Liu, Z.; Chong, Y.-L. F.; Kang, B.-H.
10.1101/2021.12.01.470752 — plant biology — Posted on 2021-12-01
3827 A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma
PAL, S.; Kaplan, J. P.; Nguyen, H.; Stopka, S. A.; Regan, M. S.; Nguyen, Q.-D.; Jones, K. L.; Moreau, L. A.; Perciaccante, A.; Hunsel, B.; Liu, K. X.; Peng, J.; Filbin, M. G.; Agar, N.; Chowdhury, D.; Haas-Kogan, D.
10.1101/2021.11.30.470644 — cancer biology — Posted on 2021-12-01
3828 An in vitro, in utero and in silico framework of oxygen diffusion in intricate vascular networks of the placenta
Bappoo, N.; Kelsey, L. J.; Tongpob, Y.; Feindel, K. W.; Caddy, H.; Wyrwoll, C. S.; Doyle, B. J.
10.1101/2021.12.01.470714 — bioengineering — Posted on 2021-12-01
3829 Chromosome-level reference genomes for two strains of Caenorhabditis briggsae: an improved platform for comparative genomics
Stevens, L.; Moya, N. D.; Tanny, R. E.; Gibson, S. B.; Tracey, A.; Na, H.; Zhan, Y.; Chitrakar, R.; Dekker, J.; Walhout, A. J.; Baugh, L. R.; Andersen, E. C.
10.1101/2021.12.01.470807 — genomics — Posted on 2021-12-01
3832 Cellular selectivity of STING stimulation determines priming of tumor-specific T cell responses
Jneid, B.; Bochnakian, A.; Delisle, F.; Djacoto, E.; Denizeau, J.; Sedlik, C.; Fiore, F.; Kramer, R.; Walters, I.; Carlioz, S.; Malissen, B.; Piaggio, E.; Manel, N.
10.1101/2021.12.01.469893 — immunology — Posted on 2021-12-01
3835 iDEP-assisted isolation of insulin secretory vesicles
Barekatain, M.; Liu, Y.; Wang, Z.; Cherezov, V.; Fraser, S.; White, K. L.; Hayes, M. A.
10.1101/2021.12.01.470798 — biophysics — Posted on 2021-12-01
3837 Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1
Weaver, T. M.; Click, T. H.; Khoang, T. H.; Washington, T. M.; Agarwal, P.; Freudenthal, B. D.
10.1101/2021.12.01.470840 — biochemistry — Posted on 2021-12-01
3838 Allosteric Regulation of Human Plastins
Schwebach, C.; Kudryashova, E.; Agrawal, R.; Zheng, W.; Egelman, E. H.; KUDRYASHOV, D. S.
10.1101/2021.12.01.470822 — biochemistry — Posted on 2021-12-01
3840 Barcode aware adaptive sampling for Oxford Nanopore sequencers.
Payne, A.; Munro, R.; Holmes, N.; Moore, C.; Carlile, M.; Loose, M. W.
10.1101/2021.12.01.470722 — genomics — Posted on 2021-12-01
3842 Single-cell transcriptome reveals insights into the development and function of the zebrafish ovary
Liu, Y.; Kossack, M. E.; Mcfaul, M. E.; Christensen, L. N.; Siebert, S.; Wyatt, S. R.; Kamei, C.; Horst, S.; Arroy, N.; Drummond, I.; Juliano, C. E.; Draper, B. W.
10.1101/2021.12.01.470669 — developmental biology — Posted on 2021-12-01
3843 ESR2 regulates indian hedgehog signaling in neonatal rat ovary
Dilower, I.; Chakravarthi, V. R. P.; Lee, E. B.; Ghosh, S.; Borosha, S.; Roy, R.; Masumi, S.; Paul, A.; Ghosh, H.; Wolfe, M. W.; Rumi, M. K.
10.1101/2021.12.01.470808 — developmental biology — Posted on 2021-12-01
3844 Paracrine role for endothelial IGF-1 receptor in white adipocyte beiging
Haywood, N. J.; Bridge, K.; Luk, C.; Warmke, N.; Simmons, K.; Drozd, M.; Moron, A.; Straw, S.; Scragg, J.; Smith, J.; Limumpornpetch, S.; Ozber, C.; Wilkinson, C.; Skromna, A.; Makava, N.; Walker, A. M. N.; Watt, N.; Mughal, R.; Griffin, K.; viswambharan, H.; Yuldasheva, N.; Beech, D. J.; Sukumar, P.; Vidal-Puig, A.; Witte, K.; Wheatcroft, S.; Cubbon, R.; Roberts, L.; Kearney, M.
10.1101/2021.12.01.470734 — cell biology — Posted on 2021-12-01
3847 Distinct ribosome states trigger diverse mRNA quality control pathways
Veltri, A. J.; D'Orazio, K. N.; Lessen, L. N.; Loll-Krippleber, R.; Brown, G. W.; Green, R.
10.1101/2021.12.01.470814 — molecular biology — Posted on 2021-12-01
3848 A Co-abundant Gene Analysis for Identification of Gut Microbial Strains Associated with Immune Responses to Oral Cholera Vaccine
Heller, F. J.; Banna, H. A.; Kaisar, M. H.; Chac, D.; Chowdhury, F.; Bhuiyan, T. R.; Akter, A.; Khan, A. I.; Karmakar, P. C.; Dash, P.; LaRocque, R. C.; Ryan, E. T.; Minot, S. S.; Harris, J. B.; Qadri, F.; Weil, A. A.
10.1101/2021.12.01.470820 — microbiology — Posted on 2021-12-01
3851 Broad human and animal coronavirus neutralisation by SARS-CoV-2 S2-targeted vaccination
Ng, K.; Faulkner, N.; Finsterbusch, K.; Wu, M.; Harvey, R.; Hussain, S.; Greco, M.; Liu, Y.; Kjaer, S.; Swanton, C.; Gandhi, S.; Beale, R.; Gamblin, S.; Cherepanov, P.; Mccauley, J.; Daniels, R.; Howell, M.; Arase, H.; Wack, A.; Bauer, D.; Kassiotis, G.
10.1101/2021.11.30.470568 — immunology — Posted on 2021-12-01
3852 Temporally stable beta sensorimotor oscillations and cortico-muscular coupling underlie force steadiness
Mongold, S. J.; Piitulainen, H.; Legrand, T.; Vander Ghinst, M.; Naeije, G.; Jousmaki, V.; Bourguignon, M.
10.1101/2021.11.30.470537 — neuroscience — Posted on 2021-12-01
3854 Cytolysin-positive Enterococcus faecalis is elevated in patients with chronic alcoholic pancreatitis
Perrin, C.; Rebours, V.; Trainel, N.; Voican, C. S.; Perlemuter, G.; Cassard, A.-M.; Ciocan, D.
10.1101/2021.11.30.468848 — physiology — Posted on 2021-12-01
3856 Harbingers of Aggressive Prostate Cancer: Precision Oncology Case Studies
Cyrta, J.; Prandi, D.; Arora, A.; Hovelson, D. H.; Sboner, A.; Rodriguez, A.; Fedrizzi, T.; Beltran, H.; Robinson, D. R.; Gopalan, A.; True, L.; Nelson, P.; Robinson, B. D.; Mosquera, J. M.; Tomlins, S.; Shen, R.; Demichelis, F. S.; Rubin, M.
10.1101/2021.11.30.468210 — cancer biology — Posted on 2021-12-01
3857 SARS-CoV-2 variants impact RBD conformational dynamics and ACE2 accessibility
Valerio, M. F.; Borges-Araujo, L.; Melo, M. N.; Lousa, D.; Soares, C.
10.1101/2021.11.30.470470 — biophysics — Posted on 2021-12-01
3858 Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane adenylyl cyclases
Mehta, V.; Khanppnavar, B.; Schuster, D.; Vercellino, I.; Kosturanova, A.; Iype, T.; Stefanic, S.; Picotti, P.; Korkhov, V. M.
10.1101/2021.12.01.470738 — biochemistry — Posted on 2021-12-01
3861 Human ventromedial prefrontal cortex lesions enhance expectation-related pain modulation
Motzkin, J. C.; Hiser, J.; Carroll, I.; Wolf, R.; Baskaya, M. K.; Koenigs, M.; Atlas, L. Y.
10.1101/2021.11.30.470579 — neuroscience — Posted on 2021-12-01
3863 Neural basis for anxiety and anxiety-related physiological responses during simulated driving: An fMRI study
Sasaoka, T.; Harada, T.; Sato, D.; Michida, N.; Yonezawa, H.; Takayama, M.; Nouzawa, T.; Yamawaki, S.
10.1101/2021.11.30.470539 — neuroscience — Posted on 2021-12-01
3865 Strength-frequency curve for micromagnetic neurostimulation through EPSPs on rat hippocampal neurons and numerical modeling of magnetic microcoil (μcoil)
Saha, R.; Faramarzi, S.; Bloom, R. P.; Benally, O. J.; Wu, K.; Girolamo, A. d.; Tonini, D.; Keirstead, S. A.; Low, W. C.; Netoff, T. I.; Wang, J.-P.
10.1101/2021.11.30.470598 — bioengineering — Posted on 2021-12-01
3867 Comparative proteogenomics deciphers the origin and evolution of eukaryotic chromatin
Grau-Bove, X.; Navarrete, C.; Chiva, C.; Pribasnig, T.; Anto, M.; Torruella, G.; Galindo, L. J.; Lang, B. F.; Moreira, D.; Lopez-Garcia, P.; Ruiz-Trillo, I.; Schleper, C.; Sabido, E.; Sebe-Pedros, A.
10.1101/2021.11.30.470311 — evolutionary biology — Posted on 2021-12-01
3870 Repeated genetic adaptation to high altitude in two tropical butterflies
Montejo-Kovacevich, G.; Meier, J. I.; Bacquet, C. N.; Warren, I. A.; Chan, Y. F.; Kucka, M.; Salazar, C.; Rueda, N.; Montgomery, S. H.; McMillan, W. O.; Kozak, K. M.; Nadeau, N. J.; Martin, S. H.; Jiggins, C. D.
10.1101/2021.11.30.470630 — evolutionary biology — Posted on 2021-12-01
3871 CADHERIN mediated AMIS localisation
Liang, X.; Weberling, A.; Hii, C. Y.; Zernicka-Goetz, M.; Buckley, C. E.
10.1101/2021.11.30.470571 — developmental biology — Posted on 2021-12-01
3872 Tertiary lymphoid structures induced by CXCL13-producing CD4+ T cells increase tumor infiltrating CD8+ T cells and B cells in ovarian cancer
Ukita, M.; Hamanishi, J.; Yoshitomi, H.; Yamanoi, K.; Takamatsu, S.; Ueda, A.; Suzuki, H.; Hosoe, Y.; Furutake, Y.; Taki, M.; Abiko, K.; Yamaguchi, K.; Nakai, H.; Baba, T.; Matsumura, N.; Yashizawa, A.; Ueo, H.; Mandai, M.
10.1101/2021.12.01.470493 — immunology — Posted on 2021-12-01
3877 AP2/ERF transcription factor NbERF-IX-33 is involved in the regulation of phytoalexin production for the resistance of Nicotiana benthamiana to Phytophthora infestans.
Imano, S.; Fushimi, M.; Camagna, M.; Tsuyama-Koike, A.; Mori, H.; Ashida, A.; Tanaka, A.; Sato, I.; Chiba, S.; Kawakita, K.; Ojika, M.; Takemoto, D.
10.1101/2021.11.30.468885 — plant biology — Posted on 2021-12-01
3878 Chitin-induced systemic disease resistance in rice requires both OsCERK1 and OsCEBiP and is mediated via perturbation of cell-wall biogenesis in leaves
Takagi, M.; Hotamori, K.; Naito, K.; Matsukawa, S.; Egusa, M.; Nishizawa, Y.; Kanno, Y.; Seo, M.; Ifuku, S.; Mine, A.; Kaminaka, H.
10.1101/2021.11.30.470685 — plant biology — Posted on 2021-12-01
3880 De Novo Pyrimidine Synthesis is a Targetable Vulnerability in IDH Mutant Glioma
Shi, D. D.; Savani, M. R.; Levitt, M. M.; Wang, A. C.; Endress, J. E.; Bird, C. E.; Buehler, J.; Stopka, S. A.; Regan, M. S.; Lin, Y.-F.; Gao, W.; Khanal, J.; Xu, M.; Huang, B.; Jennings, R. B.; Bonal, D. M.; Martin-Sandoval, M. S.; Dang, T.; Gattie, L. C.; Lee, S.; Asara, J. M.; Kornblum, H. I.; Mak, T. W.; Looper, R. E.; Nguyen, Q.-D.; Signoretti, S.; Gradl, S.; Sutter, A.; Jeffers, M.; Janzer, A.; Lehrman, M. A.; Zacharias, L. G.; Mathews, T. P.; Richardson, T. E.; Cahill, D. P.; DeBerardinis, R. J.; Ligon, K. L.; Ly, P.; Agar, N. Y. R.; Abdullah, K. G.; Harris, I. S.; Kaelin, W. G.; McBray
10.1101/2021.11.30.470443 — cancer biology — Posted on 2021-12-01
3881 Inverse PI by NMR: Analysis of Ligand 1H-Chemical Shifts in the Protein-Bound State
Platzer, G.; Mayer, M.; Boettcher, J.; Geist, L.; Fuchs, J. E.; McConnell, D. B.; Konrat, R.
10.1101/2021.11.30.470546 — biophysics — Posted on 2021-12-01
3882 Interplay between PML NBs and HIRA for H3.3 deposition on transcriptionally active interferon-stimulated genes
Kleijwegt, C.; Bressac, F.; Cohen, C.; Texier, P.; Simonet, T.; Schaeffer, L.; Lomonte, P.; Corpet, A.
10.1101/2021.11.30.470516 — genetics — Posted on 2021-12-01
3884 Does heat tolerance actually predict geographic thermal limits of animal species?
Camacho, A.; Rodrigues, M. T.; Jayyusi, R.; Harun, M.; Geraci, M.; Vinagre, C.; Carretero, M. A.; Tejedo, M. M.
10.1101/2021.11.30.468083 — ecology — Posted on 2021-12-01
3886 Invertebrate-induced priority effects and secondary metabolites control fungal community composition in dead wood
Lunde, L.; Jacobsen, R.; Kauserud, H.; Boddy, L.; Nybakken, L.; Sverdrup-Thygeson, A.; Birkemoe, T.
10.1101/2021.12.01.470726 — ecology — Posted on 2021-12-01
3888 Label-free characterisation of amyloids and alpha-Synuclein polymorphs by exploiting their intrinsic fluorescence property
Chung, C. W.; Stephens, A. D.; Ward, E.; Feng, Y.; Davis, M. J.; Kaminski, C. F.; Kaminski Schierle, G. S.
10.1101/2021.11.30.470691 — molecular biology — Posted on 2021-12-01
3889 Metabolite Damage and Damage-Control in a Minimal Genome
Haas, D.; Thamm, A. M.; Sun, J.; Huang, L.; Sun, L.; Beaudoin, G. A. W.; Wise, K. S.; Lerma-Ortiz, C.; Bruner, S. D.; Breuer, M.; Luthey-Schulten, Z.; Lin, J.; Wilson, M. A.; Brown, G.; Yakunin, A. F.; Inna Kurilyak, I.; Folz, J.; Fiehn, O.; Glass, J. I.; Hanson, A. D.; Henry, C. S.; de Crecy-Lagard, V.
10.1101/2021.12.01.470718 — microbiology — Posted on 2021-12-01
3890 Discovering tumor-reactive T-cell receptors through single-cell sequencing of tumor-infiltrating lymphocytes
Gottschalk, E.; Aksoy, B. A.; Aksoy, P.; Swiderska-Syn, M.; Mart, C.; Macpherson, L.; Romeo, M.; Smith, A.; Knochelmann, H.; Paulos, C.; Timmers, C.; Wrangle, J.; Rubinstein, M. P.; Hammerbacher, J.
10.1101/2021.11.30.470597 — immunology — Posted on 2021-12-01
3891 The Long Noncoding RNA FEDORA is a Cell-Type- and Sex-Specific Regulator of Depression
Issler, O.; van der Zee, Y. Y.; Ramakrishnan, A.; Xia, S.; Zinsmaier, A. K.; Tan, C.; Li, W.; Browne, C. J.; Walker, D. M.; Salery, M.; Torres-Berrio, A.; Futamura, R.; Duffy, J. E.; Labonte, B.; Tamminga, C. A.; Dupree, J. L.; Dong, Y.; Murrough, J. W.; Shen, L.; Nestler, E. J.
10.1101/2021.11.30.470628 — neuroscience — Posted on 2021-12-01
3894 Black-box testing in motor sequence learning
Maceira-Elvira, P.; Timmermann, J. E.; Popa, T.; Schmid, A.-C.; Krakauer, J. W.; Morishita, T.; Wessel, M. J.; Hummel, F. C.
10.1101/2021.12.01.470563 — neuroscience — Posted on 2021-12-01
3895 Spatiotemporal NF-κB dynamics encodes the position, amplitude and duration of local immune inputs
Son, M.; Frank, T.; Holst-Hansen, T.; Wang, A. G.; Junkin, M.; Kashaf, S. S.; Trusina, A.; Tay, S.
10.1101/2021.11.30.470463 — systems biology — Posted on 2021-12-01
3899 15N metabolic labeling quantification workflow in Arabidopsis using Protein Prospector
Shrestha, R.; Reyes, A. V.; Baker, P. R.; Wang, Z.-Y.; Chalkley, R. J.; Xu, S.-L.
10.1101/2021.11.30.470624 — plant biology — Posted on 2021-12-01
3901 Skeletal muscle releases extracellular vesicles with distinct protein and miRNA signatures that accumulate and function within the muscle microenvironment
Watanabe, S.; Sudo, Y.; Kimura, S.; Tomita, K.; Noguchi, M.; Sakurai, H.; Shimizu, M.; Takahashi, Y.; Sato, R.; Yamauchi, Y.
10.1101/2021.11.30.470551 — physiology — Posted on 2021-12-01
3902 Potassium effects on NCC are attenuated during inhibition of Cullin E3-ubiquitin ligases
Murali, S. K.; Little, R.; Poulsen, S. B.; Ferdaus, M.; Ellison, D. H.; McCormick, J. A.; Fenton, R. A.
10.1101/2021.11.30.470531 — physiology — Posted on 2021-12-01
3904 Insights into energy balance dysregulation from a mouse model of methylmalonic aciduria
Lucienne, M.; Gerlini, R.; Rathkolb, B.; Calzada-Wack, J.; Forny, P.; Wüest, S.; Kaech, A.; Traversi, F.; Forny, M.; Bürer, C.; Aguilar-Pimentel, J. A.; Irmler, M.; Beckers, J.; Sauer, S.; Kölker, S.; Dewulf, J. P.; Bommer, G. T.; Hoces, D.; Gailus-Durner, V.; Fuchs, H.; Rozman, J.; Froese, D. S.; Baumgartner, M. R.; Hrabe de Angelis, M.
10.1101/2021.11.30.470541 — physiology — Posted on 2021-12-01
3905 MK2 Expression Promotes Non-Small Cell Lung Cancer Cell Death and Predicts Survival
Del Rosario, O.; Suresh, K.; Kallem, M.; Singh, G.; Shah, A.; Xin, Y.; Philip, N.; D'Alessio, F.; Srivastava, M.; Bera, A.; Shimoda, L.; Merchant, M.; Rane, M.; Machamer, C.; Mock, J.; Hagan, R.; Kolb, T.; Damarla, M.
10.1101/2021.11.30.470656 — cancer biology — Posted on 2021-12-01
3906 Uveal Melanoma: a miR-16 disease?
Quemener, A. M.; Bachelot, L.; Aubry, M.; Avner, S.; Leclerc, D.; Salbert, G.; Cabillic, F.; Decaudin, D.; Mari, B.; Mouriaux, F.; Galibert, M.-D.; Gilot, D.
10.1101/2021.11.30.470499 — cancer biology — Posted on 2021-12-01
3912 Therapeutic downregulation of neuronal PAS domain 2 (Npas2) promotes surgical skin wound healing
Shibuya, Y.; Hokugo, A.; Okawa, H.; Kondo, T.; Khalil, D.; Wang, L.; Roca, Y.; Clements, A.; Sasaki, H.; Berry, E.; Nishimura, I.; Jarrahy, R.
10.1101/2021.11.29.469323 — bioengineering — Posted on 2021-12-01
3914 Optogenetic operated probiotics to regulate host metabolism by mimicking enteroendocrine
Zhang, X.; Ma, N.; Ling, W.; Pang, G.; Sun, T.; Liu, J.; Pan, H.; Cui, M.; Han, C.; Yang, C.; Chang, J.; Huang, X.; Wang, H.
10.1101/2021.11.30.470589 — bioengineering — Posted on 2021-12-01
3920 Comparative genomics of Nocardia seriolae reveals recent importation and subsequent widespread dissemination in mariculture farms in South Central Coast, Vietnam
Le, C. T.; Price, E. P.; Sarovich, D. S.; Nguyen, T. T. A.; Powell, D.; Vu-Khac, H.; Kurtboke, I.; Knibb, W.; Chen, S.-C.; Katouli, M.
10.1101/2021.11.30.470482 — genomics — Posted on 2021-12-01
3922 Raman2RNA: Live-cell label-free prediction of single-cell RNA expression profiles by Raman microscopy
Kobayashi-Kirschvink, K. J.; Gaddam, S.; James-Sorenson, T.; Grody, E.; Ounadjela, J. R.; Ge, B.; Zhang, K.; Kang, J. W.; Xavier, R.; So, P. T. C.; Biancalani, T.; Shu, J.; Regev, A.
10.1101/2021.11.30.470655 — genomics — Posted on 2021-12-01
3924 The three-dimensional chromatin structure of the major human pancreatic cell types reveals lineage-specific regulatory architecture of T2D risk
Chun, S.; Gao, L.; May, C. L.; Pippin, J. A.; Boehm, K.; Lee, M.; Liu, C.; Pahl, M.; Golson, M. L.; Naji, A.; The Human Pancreas Analysis Consortium, ; Grant, S. F. A.; Wells, A. D.; Kaestner, K. H.
10.1101/2021.11.30.470653 — genetics — Posted on 2021-12-01
3929 Australia as a global sink for the genetic diversity of avian influenza A virus
Wille, M.; Grillo, V.; Ban de Gouvea Pedroso, S.; Burgess, G. W.; Crawley, A.; Dickason, C.; Hansbro, P. M.; Hoque, M. A.; Horwood, P. F.; Kirkland, P. D.; Kung, N. Y.-H.; Lynch, S. E.; Martin, S.; McArthur, M.; ORiley, K.; Read, A. J.; Warner, S.; Hoye, B. J.; Lisovski, S.; Leen, T.; Hurt, A. C.; Butler, J.; Broz, I.; Davies, K. R.; Mileto, P.; Neave, M.; Stevens, V.; Breed, A.; Lam, T. T. Y.; Holmes, E. C.; Klaassen, M.; Wong, F. Y. K.
10.1101/2021.11.30.470533 — evolutionary biology — Posted on 2021-12-01
3930 Genetic assimilation of ancestral plasticity during parallel adaptation
Wood, D.; Holmberg, J. A.; Osborne, O. G.; Helmsetter, A. J.; Dunning, L. T.; Ellison, A. R.; Smith, R. J.; Lighten, J.; Papadopulos, A. S. T.
10.1101/2021.11.30.470425 — evolutionary biology — Posted on 2021-12-01
3932 Socioeconomics drive population change in the world's largest carnivores
Johnson, T. F.; Isaac, N. J. B.; Paviolo, A.; Gonzalez-Saurez, M.
10.1101/2021.11.30.470341 — ecology — Posted on 2021-12-01
3933 A single-cell transcriptome atlas of human early embryogenesis
Xu, Y.; Zhang, T.; Zhou, Q.; Hu, M.; Qi, Y.; Xue, Y.; Wang, L.; Bao, Z.; Shi, W.
10.1101/2021.11.30.470583 — developmental biology — Posted on 2021-12-01
3936 Nanoscale structural organization and stoichiometry of the budding yeast kinetochore
Cieslinski, K.; Wu, Y.-L.; Neechyporenko, L.; Hoerner, S. J.; Conti, D.; Ries, J.
10.1101/2021.12.01.469648 — cell biology — Posted on 2021-12-01
3937 Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling
Lyu, Z.; Sycks, M. M.; Espinoza, M. F.; Nguyen, K. K.; Galapate, C. M.; Mei, L.; Genereux, J. C.
10.1101/2021.11.30.470448 — molecular biology — Posted on 2021-12-01
3939 Babesia duncani as a model organism to study the development, virulence and drug susceptibility of intraerythrocytic parasites in vitro and in vivo
Mamoun, C.; Pal, A. C.; Renard, I.; Singh, P.; Vydyam, P.; Chiu, J. E.; Pou, S.; W. Winter, R.; Dodean, R.; Frueh, L.; Nilsen, A. C.; Riscoe, M. K.; Doggett, J. S.
10.1101/2021.12.01.470698 — microbiology — Posted on 2021-12-01
3940 Microbial cysteine degradation is a source of hydrogen sulfide in oxic freshwater lakes
Tran, P. Q.; Bachand, S. C.; Hotvedt, J. C.; Kieft, K.; McDaniel, E. A.; McMahon, K. D.; Anantharaman, K.
10.1101/2021.11.30.467465 — microbiology — Posted on 2021-12-01
3941 Efficient targeting of NY-ESO-1 tumor antigen to human cDC1s by lymphotactin results in cross-presentation and antigen-specific T cell expansion
Le Gall, C. M.; Cammarata, A.; de Haas, L.; Ramos-Tomillero, I.; Cuenca-Escalona, J.; Wijfjes, Z.; Becker, A. M. D.; Dolen, Y.; de Vries, I. J. M.; Figdor, C. G.; Florez-Grau, G.; Verdoes, M.
10.1101/2021.11.30.470538 — immunology — Posted on 2021-12-01
3943 Convergent Cerebrospinal Fluid Proteomes and Metabolic Ontologies in Humans and Animal Models of Rett Syndrome
Zlatic, S. A.; Duong, D.; Gadalla, K. K.; Murage, B.; Ping, L.; Shah, R.; Khwaja, O.; Swanson, L. C.; Sahin, M.; Rayaprolu, S.; Kumar, P.; Rangaraju, S.; Bird, A. P.; Tarquinio, D.; Cobb, S.; Faundez, V.
10.1101/2021.11.30.470580 — neuroscience — Posted on 2021-12-01
3945 Social-vocal brain networks in a non-human primate
Takahashi, D. Y.; El Hady, A.; Zhang, Y. S.; Liao, D. A.; Montaldo, G.; Urban, A.; Ghazanfar, A. A.
10.1101/2021.12.01.470701 — neuroscience — Posted on 2021-12-01
3946 Oligodendrocytes are a lifelong source of nuclear and ribosomal material for neurons in the mouse brain
Mayrhofer, F.; Hanson, A. M.; Falcone, C.; Xiang, Y. K.; Navedo, M. F.; Deng, W.; Chechneva, O.
10.1101/2021.11.30.470658 — neuroscience — Posted on 2021-12-01
3947 Microglial MorphOMICs unravel region- and sex-dependent morphological phenotypes from postnatal development to degeneration
Colombo, G.; Cubero, R. J. A.; Kanari, L.; Venturino, A.; Schulz, R.; Scolamiero, M.; Agerberg, J.; Mathys, H.; Tsai, L.-H.; Chacholski, W.; Hess, K.; Siegert, S.
10.1101/2021.11.30.470610 — neuroscience — Posted on 2021-12-01
3951 Tandem WW/PPxY motif interactions in WWOX: the multifaceted role of the second WW domain
Rotem-Bamberger, S.; Fahoum, J.; Keinan-Adamsky, K.; Tsaban, T.; Avraham, O.; Shalev, D. E.; Chill, J. H.; Schueler-Furman, O.
10.1101/2021.12.01.470705 — biophysics — Posted on 2021-12-01
3958 Low ozone concentration and negative ions for rapid SARS-CoV-2 inactivation
De Forni, D.; Poddesu, B.; Cugia, G.; Gallizia, G.; La Licata, M.; Lisziewicz, J.; Chafouleas, J.; Lori, F.
10.1101/2021.03.11.434968 — microbiology — Posted on 2021-12-01
3961 The Importance of Mentors and How to Handle More Than One Mentor
Marshall, A. G.; Brady, L.; Palavicino-Maggio, C.; Neikirk, K.; Vue, Z.; Beasley, H.; Garza Lopez, E.; Murray, S.; Martinez, D.; Shuler, H.; Spencer, E.; Morton, D.; Hinton, A.
10.1101/2021.11.29.469764 — scientific communication and education — Posted on 2021-12-01
3962 Using a Champion-Oriented Mindset to Overcome the Challenges of Graduate School
Marshall, A.; Palavicino-Maggio, C.; Neikirk, K.; Vue, Z.; Beasley, H.; Lopez, E. G.; Murray, S. A.; Martinez, D.; Davis, J.; Shuler, H.; Spencer, E.; Morton, D.; Hinton, A.
10.1101/2021.11.29.469904 — scientific communication and education — Posted on 2021-12-01
3971 Adolescent rats extend help to outgroup members, highlighting a neural network for group identity categorization.
Breton, J.; Eisner, J. S.; Gandhi, V. S.; Musick, N.; Zhang, A.; Long, K. L. P.; Perloff, O. S.; Hu, K. Y.; Pham, C. M.; Lalchandani, P.; Barraza, M. K.; Kantor, B.; Kaufer, D.; Ben-Ami Bartal, I.
10.1101/2021.11.29.470434 — neuroscience — Posted on 2021-12-01
3972 Neuropeptide signalling shapes feeding and reproductive behaviours in male C. elegans
Gadenne, M. J.; Hardege, I.; Suleski, D.; Jaggers, P.; Beets, I.; Schafer, W. R.; Chew, Y. L.
10.1101/2021.11.29.470485 — neuroscience — Posted on 2021-12-01
3974 ACTIN Anchors the Highly Oligomeric DRP1 at Mitochondria-Sarcoplasmic Reticulum Contact Sites in Adult Murine Heart: Its Functional Implication
Fernandez Sanz, C.; De la Fuente Perez, S.; Nichtova, Z.; Yuan, Y.; Lanvermann, S.; Tsai, H.-Y.; Ferderico, M.; Xin, Y.; Csordas, G.; Wang, W.; Mourier, A.; Sheu, S.-S.
10.1101/2021.11.29.470468 — physiology — Posted on 2021-12-01
3976 GraphPrompt: Biomedical Entity Normalization Using Graph-based Prompt Templates
Zhang, J.; Wang, Z.; Zhang, S.; Bhalerao, M. M.; Liu, Y.; Zhu, D.; Wang, S.
10.1101/2021.11.29.470486 — bioinformatics — Posted on 2021-12-01
3978 Genetic architecture and genomic prediction accuracy of apple quantitative traits across environments
Jung, M.; Keller, B.; Roth, M.; Aranzana, M. J.; Auwerkerken, A.; Guerra, W.; Al-Rifai, M.; Lewandowski, M.; Sanin, N.; Rymenants, M.; Didelot, F.; Dujak, C.; Font i Forcada, C.; Knauf, A.; Laurens, F.; Studer, B.; Muranty, H.; Patocchi, A.
10.1101/2021.11.29.470309 — genomics — Posted on 2021-12-01
3979 Rapid multilocus adaptation of clonal cabbage leaf curl virus populations to Arabidopsis thaliana
Hoyer, J. S.; Wilkins, O. W.; Munshi, A.; Wiese, E.; Dubey, D.; Renard, S.; Mortensen, K. R. H.; Dye, A. E.; Carbone, I.; Duffy, S.; Ascencio-Ibanez, J. T.
10.1101/2021.11.29.468282 — evolutionary biology — Posted on 2021-12-01
3986 Transcriptional adaptation of sensory neurons to GPCR identity and activity
Horgue, L. F.; Assens, A.; Fodoulian, L.; Archinto, L. M.; Tuberosa, J.; Haider, A.; Boillat, M. K.; Carleton, A.; Rodriguez, I.
10.1101/2021.11.29.468971 — neuroscience — Posted on 2021-12-01
3988 Micronized curcumin causes hyperlocomotion in zebrafish larvae
Sachett, A.; Benvenutti, R.; Reis, C. G.; Gallas-Lopes, M.; Bastos, L. M.; Aguiar, G. P. S.; Herrmann, A. P.; Oliveira, J. V.; Siebel, A. M.; Piato, A.
10.1101/2021.11.29.470475 — neuroscience — Posted on 2021-12-01
3992 Conformational Tuning of Amylin by Charged Styrene-maleic-acid Copolymers
Sahoo, B.; Souders, C.; Nakayama, T.; Deng, Z.; Linton, H.; Suladze, S.; Ivanova, M.; Reif, B.; Ando, T.; Martyniuk, C.; Ramamoorthy, A.
10.1101/2020.04.23.057547 — biophysics — Posted on 2021-12-01
3995 Replication Study: RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth
Pelech, S.; Gallagher, C.; Sutter, C.; Yue, L.; Kerwin, J.; Bhargava, A.; Iorns, E.; Tsui, R.; Denis, A.; Perfito, N.; Errington, T. M.
10.1101/2021.11.30.470372 — cancer biology — Posted on 2021-12-01
3997 Differentially optimized cell-free buffer enables robust expression from unprotected linear DNA in exonuclease-deficient extracts
Batista, A. C.; Levrier, A.; Soudier, P.; Voyvodic, P. L.; Achmedov, T.; Reif-Trauttmansdorff, T.; DeVisch, A.; Gonsaud, M. C.; Faulon, J.-L.; Beisel, C.; Bonnet, J.; Kushwaha, M.
10.1101/2021.09.07.459228 — synthetic biology — Posted on 2021-12-01
3998 Satellitome comparison of two oedipodine grasshoppers highlights the contingent nature of satellite DNA evolution
Camacho, J. P. M.; Cabrero, J.; Lopez-Leon, M. D.; Martin-Pecina, M.; Perfectti, F.; Garrido-Ramos, M. A.; Ruiz-Ruano, F. J.
10.1101/2021.07.01.450629 — genomics — Posted on 2021-12-01
4006 Universal features shaping organelle gene retention
Giannakis, K.; Arrowsmith, S. J.; Richards, L.; Gasparini, S.; Chustecki, J. M.; Royrvik, E. C.; Johnston, I. G.
10.1101/2021.10.27.465964 — evolutionary biology — Posted on 2021-12-01
4008 Heat activation and inactivation of bacterial spores. Is there an overlap?
Wen, J.; Smelt, J. P. P. M.; Vischer, N. O. E.; Vos, A. L. d.; Setlow, P.; Brul, S.
10.1101/2021.11.20.469368 — microbiology — Posted on 2021-12-01
4009 monaLisa: an R/Bioconductor package for identifying regulatory motifs
Machlab, D.; Burger, L.; Soneson, C.; Rijli, F. M.; Schubeler, D.; Stadler, M. B.
10.1101/2021.11.30.470570 — bioinformatics — Posted on 2021-12-01
4012 Insights into opium poppy (Papaver spp.) genetic diversity from genotyping-by-sequencing analysis
Hong, U. V. T.; Tamiru-Oli, M.; Hurgobin, B.; Okey, C. R.; Abreu, A. R.; Lewsey, M. G.
10.1101/2021.09.28.462245 — plant biology — Posted on 2021-12-01
4014 Salmonella enterica serovar Typhimurium from Wild Birds in the United States Represent Distinct Lineages Defined by Bird Type
Fu, Y.; M'ikanatha, N. M.; Whitehouse, C. A.; Li, S.; Deng, X.; Smith, J. C.; Shariat, N. W.; Nawrocki, E. M.; Dudley, E. G.
10.1101/2021.11.26.470158 — microbiology — Posted on 2021-12-01